#ID(s) interactor A ID(s) interactor B Alt. ID(s) interactor A Alt. ID(s) interactor B Alias(es) interactor A Alias(es) interactor B Interaction detection method(s) Publication 1st author(s) Publication Identifier(s) Taxid interactor A Taxid interactor B Interaction type(s) Source database(s) Interaction identifier(s) Confidence value(s) Expansion method(s) Biological role(s) interactor A Biological role(s) interactor B Experimental role(s) interactor A Experimental role(s) interactor B Type(s) interactor A Type(s) interactor B Xref(s) interactor A Xref(s) interactor B Interaction Xref(s) Annotation(s) interactor A Annotation(s) interactor B Interaction annotation(s) Host organism(s) Interaction parameter(s) Creation date Update date Checksum(s) interactor A Checksum(s) interactor B Interaction Checksum(s) Negative Feature(s) interactor A Feature(s) interactor B Stoichiometry(s) interactor A Stoichiometry(s) interactor B Identification method participant A Identification method participant B uniprotkb:Q2TAZ0 uniprotkb:Q9H3R5 intact:EBI-2514077|intact:EBI-28978291|uniprotkb:Q8TAI8|uniprotkb:O43154|uniprotkb:Q14DM2|uniprotkb:Q7Z6K8|uniprotkb:Q6ZTV2|uniprotkb:Q96HH7|uniprotkb:Q8IVY5|ensembl:ENSP00000366475 intact:EBI-1003700|uniprotkb:A8K3Y1|ensembl:ENSP00000283006 psi-mi:atg2a_human(display_long)|uniprotkb:ATG2A(gene name)|psi-mi:ATG2A(display_short)|uniprotkb:KIAA0404(gene name synonym) psi-mi:cenph_human(display_long)|uniprotkb:Interphase centromere complex protein 35(gene name synonym)|uniprotkb:ICEN35(gene name synonym)|uniprotkb:CENPH(gene name)|psi-mi:CENPH(display_short) psi-mi:"MI:0030"(cross-linking study) Tang et al. (2019) imex:IM-28478|pubmed:31412244 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-26443127|imex:IM-28478-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:XP_011543165.1|ensembl:ENSP00000366475|ensembl:ENST00000421419|ensembl:ENSP00000410522|refseq:NP_055919.2|ensembl:ENSG00000110046(gene)|ensembl:ENST00000377264(transcript)|go:"GO:0000045"(autophagosome assembly)|go:"GO:0000407"(phagophore assembly site)|go:"GO:0000422"(autophagy of mitochondrion)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005811"(lipid droplet)|go:"GO:0019898"(extrinsic component of membrane)|go:"GO:0032266"(phosphatidylinositol-3-phosphate binding)|go:"GO:0034045"(phagophore assembly site membrane)|go:"GO:0034727"(piecemeal microautophagy of the nucleus)|go:"GO:0044805"(late nucleophagy)|interpro:IPR015412(ATG2, C-terminal)|interpro:IPR026849|interpro:IPR026854|rcsb pdb:6KLR|go:"GO:0061709"(reticulophagy) refseq:NP_075060.1|ensembl:ENSG00000153044(gene)|ensembl:ENST00000283006(transcript)|go:"GO:0000776"(kinetochore)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005694"(chromosome)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0007052"(mitotic spindle organization)|go:"GO:0007059"(chromosome segregation)|go:"GO:0043515"(kinetochore binding)|go:"GO:0051382"(kinetochore assembly)|go:"GO:0051383"(kinetochore organization)|interpro:IPR040034|mint:Q9H3R5|reactome:R-HSA-141444|reactome:R-HSA-2467813|reactome:R-HSA-2500257|reactome:R-HSA-5663220|reactome:R-HSA-606279|reactome:R-HSA-68877|reactome:R-HSA-9648025|interpro:IPR008426(Centromere H) - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/10/21 2020/11/06 rogid:RC80jQqKw4ekVFudqz/IunWCEMA9606 rogid:NcnQtHH8NhQ2AUePTPR3TRrpqaI9606 rigid:319IsGV1oRp3OLZk5khzgtmEExU false enhanced green fluorescent protein tag:n-n|sufficient binding region:1776-1820 - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q2TAZ0 uniprotkb:O75431 intact:EBI-2514077|intact:EBI-28978291|uniprotkb:Q8TAI8|uniprotkb:O43154|uniprotkb:Q14DM2|uniprotkb:Q7Z6K8|uniprotkb:Q6ZTV2|uniprotkb:Q96HH7|uniprotkb:Q8IVY5|ensembl:ENSP00000366475 intact:EBI-7415268|uniprotkb:Q53SQ2|uniprotkb:Q5M7Z6|uniprotkb:A8JZZ4|intact:MINT-3001232|intact:MINT-4876050|uniprotkb:Q53S50|ensembl:ENSP00000249442|uniprotkb:Q8IZ68 psi-mi:atg2a_human(display_long)|uniprotkb:ATG2A(gene name)|psi-mi:ATG2A(display_short)|uniprotkb:KIAA0404(gene name synonym) psi-mi:mtx2_human(display_long)|uniprotkb:MTX2(gene name)|psi-mi:MTX2(display_short)|uniprotkb:Mitochondrial outer membrane import complex protein 2(gene name synonym) psi-mi:"MI:0030"(cross-linking study) Tang et al. (2019) imex:IM-28478|pubmed:31412244 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-26443127|imex:IM-28478-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:XP_011543165.1|ensembl:ENSP00000366475|ensembl:ENST00000421419|ensembl:ENSP00000410522|refseq:NP_055919.2|ensembl:ENSG00000110046(gene)|ensembl:ENST00000377264(transcript)|go:"GO:0000045"(autophagosome assembly)|go:"GO:0000407"(phagophore assembly site)|go:"GO:0000422"(autophagy of mitochondrion)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005811"(lipid droplet)|go:"GO:0019898"(extrinsic component of membrane)|go:"GO:0032266"(phosphatidylinositol-3-phosphate binding)|go:"GO:0034045"(phagophore assembly site membrane)|go:"GO:0034727"(piecemeal microautophagy of the nucleus)|go:"GO:0044805"(late nucleophagy)|interpro:IPR015412(ATG2, C-terminal)|interpro:IPR026849|interpro:IPR026854|rcsb pdb:6KLR|go:"GO:0061709"(reticulophagy) refseq:NP_001306026.1|refseq:NP_001306027.1|refseq:NP_001006636.1|refseq:NP_006545.1|ensembl:ENSG00000128654(gene)|ensembl:ENST00000249442(transcript)|go:"GO:0001401"(SAM complex)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0006839"(mitochondrial transport)|go:"GO:0007005"(mitochondrion organization)|go:"GO:0007007"(inner mitochondrial membrane organization)|go:"GO:0015031"(protein transport)|interpro:IPR019564|interpro:IPR033468|interpro:IPR036282|interpro:IPR040079|mint:O75431|reactome:R-HSA-1268020|reactome:R-HSA-8949613|go:"GO:0140275"(MIB complex) - - comment:mint|function:Involved in transport of proteins into the mitochondrion figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/10/21 2020/11/06 rogid:RC80jQqKw4ekVFudqz/IunWCEMA9606 rogid:M4zfGX8gfFUFW7xYoXeEzA2UCSM9606 rigid:319IsGV1oRp3OLZk5khzgtmEExU false enhanced green fluorescent protein tag:n-n|sufficient binding region:1776-1820 - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q2TAZ0 uniprotkb:Q8N4V1 intact:EBI-2514077|intact:EBI-28978291|uniprotkb:Q8TAI8|uniprotkb:O43154|uniprotkb:Q14DM2|uniprotkb:Q7Z6K8|uniprotkb:Q6ZTV2|uniprotkb:Q96HH7|uniprotkb:Q8IVY5|ensembl:ENSP00000366475 intact:EBI-6163737|ensembl:ENSP00000306220|ensembl:ENSP00000505226|uniprotkb:B2R625|uniprotkb:B4DIY3|uniprotkb:D3DWG7|uniprotkb:Q5JPP7 psi-mi:atg2a_human(display_long)|uniprotkb:ATG2A(gene name)|psi-mi:ATG2A(display_short)|uniprotkb:KIAA0404(gene name synonym) psi-mi:emc5_human(display_long)|uniprotkb:MMGT1(gene name)|psi-mi:MMGT1(display_short)|uniprotkb:TMEM32(gene name synonym)|uniprotkb:Transmembrane protein 32(gene name synonym)|uniprotkb:EMC5(gene name synonym)|uniprotkb:Membrane magnesium transporter 1(gene name synonym) psi-mi:"MI:0030"(cross-linking study) Tang et al. (2019) imex:IM-28478|pubmed:31412244 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-26443127|imex:IM-28478-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:XP_011543165.1|ensembl:ENSP00000366475|ensembl:ENST00000421419|ensembl:ENSP00000410522|refseq:NP_055919.2|ensembl:ENSG00000110046(gene)|ensembl:ENST00000377264(transcript)|go:"GO:0000045"(autophagosome assembly)|go:"GO:0000407"(phagophore assembly site)|go:"GO:0000422"(autophagy of mitochondrion)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005811"(lipid droplet)|go:"GO:0019898"(extrinsic component of membrane)|go:"GO:0032266"(phosphatidylinositol-3-phosphate binding)|go:"GO:0034045"(phagophore assembly site membrane)|go:"GO:0034727"(piecemeal microautophagy of the nucleus)|go:"GO:0044805"(late nucleophagy)|interpro:IPR015412(ATG2, C-terminal)|interpro:IPR026849|interpro:IPR026854|rcsb pdb:6KLR|go:"GO:0061709"(reticulophagy) go:"GO:0015693"(magnesium ion transport)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0022890"(inorganic cation transmembrane transporter activity)|go:"GO:0030176"(integral component of endoplasmic reticulum membrane)|go:"GO:0031901"(early endosome membrane)|go:"GO:0045050"(protein insertion into ER membrane by stop-transfer membrane-anchor sequence)|go:"GO:0071816"(tail-anchored membrane protein insertion into ER membrane)|go:"GO:0072546"(EMC complex)|interpro:IPR018937|rcsb pdb:6WW7|rcsb pdb:6Z3W|rcsb pdb:7ADO|rcsb pdb:7ADP|reactome:R-HSA-5223345|ensembl:ENSG00000169446(gene)|ensembl:ENST00000305963(transcript)|ensembl:ENST00000679621(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0005769"(early endosome)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0015095"(magnesium ion transmembrane transporter activity)|refseq:NP_775741.1|refseq:NP_001316929.1 - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/10/21 2020/11/06 rogid:RC80jQqKw4ekVFudqz/IunWCEMA9606 rogid:Kq+VEYt+fwoOsEfcgZ1K1vkFFN49606 rigid:319IsGV1oRp3OLZk5khzgtmEExU false enhanced green fluorescent protein tag:n-n|sufficient binding region:1776-1820 - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q2TAZ0 uniprotkb:Q9Y6C9 intact:EBI-2514077|intact:EBI-28978291|uniprotkb:Q8TAI8|uniprotkb:O43154|uniprotkb:Q14DM2|uniprotkb:Q7Z6K8|uniprotkb:Q6ZTV2|uniprotkb:Q96HH7|uniprotkb:Q8IVY5|ensembl:ENSP00000366475 intact:EBI-6164522|ensembl:ENSP00000303222|ensembl:ENSP00000495027|uniprotkb:B2R7L8 psi-mi:atg2a_human(display_long)|uniprotkb:ATG2A(gene name)|psi-mi:ATG2A(display_short)|uniprotkb:KIAA0404(gene name synonym) psi-mi:mtch2_human(display_long)|uniprotkb:MTCH2(gene name)|psi-mi:MTCH2(display_short)|uniprotkb:MIMP(gene name synonym)|uniprotkb:Met-induced mitochondrial protein(gene name synonym)|uniprotkb:HSPC032(orf name) psi-mi:"MI:0030"(cross-linking study) Tang et al. (2019) imex:IM-28478|pubmed:31412244 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-26443127|imex:IM-28478-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:XP_011543165.1|ensembl:ENSP00000366475|ensembl:ENST00000421419|ensembl:ENSP00000410522|refseq:NP_055919.2|ensembl:ENSG00000110046(gene)|ensembl:ENST00000377264(transcript)|go:"GO:0000045"(autophagosome assembly)|go:"GO:0000407"(phagophore assembly site)|go:"GO:0000422"(autophagy of mitochondrion)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005811"(lipid droplet)|go:"GO:0019898"(extrinsic component of membrane)|go:"GO:0032266"(phosphatidylinositol-3-phosphate binding)|go:"GO:0034045"(phagophore assembly site membrane)|go:"GO:0034727"(piecemeal microautophagy of the nucleus)|go:"GO:0044805"(late nucleophagy)|interpro:IPR015412(ATG2, C-terminal)|interpro:IPR026849|interpro:IPR026854|rcsb pdb:6KLR|go:"GO:0061709"(reticulophagy) interpro:IPR018108|interpro:IPR023395|mint:Q9Y6C9|go:"GO:0070585"(protein localization to mitochondrion)|ensembl:ENSG00000109919(gene)|ensembl:ENSG00000285121(gene)|ensembl:ENST00000302503(transcript)|ensembl:ENST00000643223(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0043065"(positive regulation of apoptotic process)|refseq:NP_001304160.1|refseq:NP_001304161.1|refseq:NP_001304162.1|refseq:NP_055157.1 - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/10/21 2020/11/06 rogid:RC80jQqKw4ekVFudqz/IunWCEMA9606 rogid:Lbg7MBRn09cRzoYOiSt4g4FjsjA9606 rigid:319IsGV1oRp3OLZk5khzgtmEExU false enhanced green fluorescent protein tag:n-n|sufficient binding region:1776-1820 - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q2TAZ0 uniprotkb:Q9P0I2 intact:EBI-2514077|intact:EBI-28978291|uniprotkb:Q8TAI8|uniprotkb:O43154|uniprotkb:Q14DM2|uniprotkb:Q7Z6K8|uniprotkb:Q6ZTV2|uniprotkb:Q96HH7|uniprotkb:Q8IVY5|ensembl:ENSP00000366475 intact:EBI-1054670|uniprotkb:Q53GH8|uniprotkb:Q6ZMC2|uniprotkb:B2R4Z9|ensembl:ENSP00000245046 psi-mi:atg2a_human(display_long)|uniprotkb:ATG2A(gene name)|psi-mi:ATG2A(display_short)|uniprotkb:KIAA0404(gene name synonym) psi-mi:emc3_human(display_long)|uniprotkb:EMC3(gene name)|psi-mi:EMC3(display_short)|uniprotkb:TMEM111(gene name synonym)|uniprotkb:Transmembrane protein 111(gene name synonym) psi-mi:"MI:0030"(cross-linking study) Tang et al. (2019) imex:IM-28478|pubmed:31412244 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-26443127|imex:IM-28478-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:XP_011543165.1|ensembl:ENSP00000366475|ensembl:ENST00000421419|ensembl:ENSP00000410522|refseq:NP_055919.2|ensembl:ENSG00000110046(gene)|ensembl:ENST00000377264(transcript)|go:"GO:0000045"(autophagosome assembly)|go:"GO:0000407"(phagophore assembly site)|go:"GO:0000422"(autophagy of mitochondrion)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005811"(lipid droplet)|go:"GO:0019898"(extrinsic component of membrane)|go:"GO:0032266"(phosphatidylinositol-3-phosphate binding)|go:"GO:0034045"(phagophore assembly site membrane)|go:"GO:0034727"(piecemeal microautophagy of the nucleus)|go:"GO:0044805"(late nucleophagy)|interpro:IPR015412(ATG2, C-terminal)|interpro:IPR026849|interpro:IPR026854|rcsb pdb:6KLR|go:"GO:0061709"(reticulophagy) refseq:NP_060917.1|ensembl:ENSG00000125037(gene)|ensembl:ENST00000245046(transcript)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030176"(integral component of endoplasmic reticulum membrane)|go:"GO:0045050"(protein insertion into ER membrane by stop-transfer membrane-anchor sequence)|go:"GO:0071816"(tail-anchored membrane protein insertion into ER membrane)|go:"GO:0072546"(EMC complex)|interpro:IPR002809(Protein of unknown function DUF106, transmembrane)|interpro:IPR008568(Protein of unknown function DUF850, transmembrane eukaryotic)|rcsb pdb:6WW7|rcsb pdb:6Z3W|rcsb pdb:7ADO|rcsb pdb:7ADP|reactome:R-HSA-8980692 - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/10/21 2020/11/06 rogid:RC80jQqKw4ekVFudqz/IunWCEMA9606 rogid:VbIl0nFhcDMIPTxmBclaIMtbVU09606 rigid:319IsGV1oRp3OLZk5khzgtmEExU false enhanced green fluorescent protein tag:n-n|sufficient binding region:1776-1820 - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q2TAZ0 uniprotkb:Q9NVH1 intact:EBI-2514077|intact:EBI-28978291|uniprotkb:Q8TAI8|uniprotkb:O43154|uniprotkb:Q14DM2|uniprotkb:Q7Z6K8|uniprotkb:Q6ZTV2|uniprotkb:Q96HH7|uniprotkb:Q8IVY5|ensembl:ENSP00000366475 intact:EBI-1055336|uniprotkb:Q4VWF5|uniprotkb:Q5VZN0|uniprotkb:Q6PK20|uniprotkb:Q6PK70|uniprotkb:Q8NDM2|uniprotkb:Q96CL7|ensembl:ENSP00000366800 psi-mi:atg2a_human(display_long)|uniprotkb:ATG2A(gene name)|psi-mi:ATG2A(display_short)|uniprotkb:KIAA0404(gene name synonym) psi-mi:djc11_human(display_long)|uniprotkb:DNAJC11(gene name)|psi-mi:DNAJC11(display_short) psi-mi:"MI:0030"(cross-linking study) Tang et al. (2019) imex:IM-28478|pubmed:31412244 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-26443127|imex:IM-28478-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:XP_011543165.1|ensembl:ENSP00000366475|ensembl:ENST00000421419|ensembl:ENSP00000410522|refseq:NP_055919.2|ensembl:ENSG00000110046(gene)|ensembl:ENST00000377264(transcript)|go:"GO:0000045"(autophagosome assembly)|go:"GO:0000407"(phagophore assembly site)|go:"GO:0000422"(autophagy of mitochondrion)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005811"(lipid droplet)|go:"GO:0019898"(extrinsic component of membrane)|go:"GO:0032266"(phosphatidylinositol-3-phosphate binding)|go:"GO:0034045"(phagophore assembly site membrane)|go:"GO:0034727"(piecemeal microautophagy of the nucleus)|go:"GO:0044805"(late nucleophagy)|interpro:IPR015412(ATG2, C-terminal)|interpro:IPR026849|interpro:IPR026854|rcsb pdb:6KLR|go:"GO:0061709"(reticulophagy) refseq:NP_060668.2|ensembl:ENSG00000007923(gene)|ensembl:ENST00000377577(transcript)|go:"GO:0001401"(SAM complex)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0007007"(inner mitochondrial membrane organization)|go:"GO:0016607"(nuclear speck)|go:"GO:0042407"(cristae formation)|go:"GO:0140275"(MIB complex)|interpro:IPR001623(Heat shock protein DnaJ, N-terminal)|interpro:IPR018253|interpro:IPR024586|interpro:IPR036869|mint:Q9NVH1|reactome:R-HSA-8949613 - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/10/21 2020/11/06 rogid:RC80jQqKw4ekVFudqz/IunWCEMA9606 rogid:+I9CW/QUSn5NIkn2CRTFzq50c/I9606 rigid:319IsGV1oRp3OLZk5khzgtmEExU false enhanced green fluorescent protein tag:n-n|sufficient binding region:1776-1820 - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q2TAZ0 uniprotkb:Q9Y2U8 intact:EBI-2514077|intact:EBI-28978291|uniprotkb:Q8TAI8|uniprotkb:O43154|uniprotkb:Q14DM2|uniprotkb:Q7Z6K8|uniprotkb:Q6ZTV2|uniprotkb:Q96HH7|uniprotkb:Q8IVY5|ensembl:ENSP00000366475 intact:EBI-2561428|ensembl:ENSP00000308369|uniprotkb:Q9NT47|uniprotkb:Q9NYA5 psi-mi:atg2a_human(display_long)|uniprotkb:ATG2A(gene name)|psi-mi:ATG2A(display_short)|uniprotkb:KIAA0404(gene name synonym) psi-mi:man1_human(display_long)|uniprotkb:MAN1(gene name synonym)|uniprotkb:LEM domain-containing protein 3(gene name synonym)|uniprotkb:LEMD3(gene name)|psi-mi:LEMD3(display_short) psi-mi:"MI:0030"(cross-linking study) Tang et al. (2019) imex:IM-28478|pubmed:31412244 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-26443127|imex:IM-28478-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:XP_011543165.1|ensembl:ENSP00000366475|ensembl:ENST00000421419|ensembl:ENSP00000410522|refseq:NP_055919.2|ensembl:ENSG00000110046(gene)|ensembl:ENST00000377264(transcript)|go:"GO:0000045"(autophagosome assembly)|go:"GO:0000407"(phagophore assembly site)|go:"GO:0000422"(autophagy of mitochondrion)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005811"(lipid droplet)|go:"GO:0019898"(extrinsic component of membrane)|go:"GO:0032266"(phosphatidylinositol-3-phosphate binding)|go:"GO:0034045"(phagophore assembly site membrane)|go:"GO:0034727"(piecemeal microautophagy of the nucleus)|go:"GO:0044805"(late nucleophagy)|interpro:IPR015412(ATG2, C-terminal)|interpro:IPR026849|interpro:IPR026854|rcsb pdb:6KLR|go:"GO:0061709"(reticulophagy) ensembl:ENSG00000174106(gene)|ensembl:ENST00000308330(transcript)|go:"GO:0005637"(nuclear inner membrane)|go:"GO:0005639"(integral component of nuclear inner membrane)|go:"GO:0006998"(nuclear envelope organization)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030512"(negative regulation of transforming growth factor beta receptor signaling pathway)|go:"GO:0030514"(negative regulation of BMP signaling pathway)|go:"GO:0031490"(chromatin DNA binding)|go:"GO:0032926"(negative regulation of activin receptor signaling pathway)|go:"GO:1902531"(regulation of intracellular signal transduction)|go:"GO:0031965"(nuclear membrane)|interpro:IPR003887(Lamino-associated polypeptide 2/emerin)|interpro:IPR011015(LEM-like fold)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR018996|interpro:IPR034394|interpro:IPR034997|interpro:IPR035979|interpro:IPR041885|mint:Q9Y2U8|rcsb pdb:2CH0|rcsb pdb:5ZOJ|rcsb pdb:5ZOK|reactome:R-HSA-2980766|reactome:R-HSA-2995383|reactome:R-HSA-4419969|reactome:R-HSA-9013149|reactome:R-HSA-9013404|reactome:R-HSA-9013405|reactome:R-HSA-9013408|reactome:R-HSA-9013423|reactome:R-HSA-9696264|reactome:R-HSA-9696270|reactome:R-HSA-9696273|refseq:NP_001161086.1|refseq:NP_055134.2 - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/10/21 2020/11/06 rogid:RC80jQqKw4ekVFudqz/IunWCEMA9606 rogid:8AILzxAZLbxCAzlJ7oPg9WybOmY9606 rigid:319IsGV1oRp3OLZk5khzgtmEExU false enhanced green fluorescent protein tag:n-n|sufficient binding region:1776-1820 - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q2TAZ0 uniprotkb:Q8NFQ8 intact:EBI-2514077|intact:EBI-28978291|uniprotkb:Q8TAI8|uniprotkb:O43154|uniprotkb:Q14DM2|uniprotkb:Q7Z6K8|uniprotkb:Q6ZTV2|uniprotkb:Q96HH7|uniprotkb:Q8IVY5|ensembl:ENSP00000366475 intact:EBI-524567|ensembl:ENSP00000356584|ensembl:ENSP00000477486 psi-mi:atg2a_human(display_long)|uniprotkb:ATG2A(gene name)|psi-mi:ATG2A(display_short)|uniprotkb:KIAA0404(gene name synonym) psi-mi:toip2_human(display_long)|uniprotkb:Lumenal domain-like LAP1(gene name synonym)|uniprotkb:TOR1AIP2(gene name)|psi-mi:TOR1AIP2(display_short)|uniprotkb:LULL1(gene name synonym)|uniprotkb:IFRG15(gene name synonym) psi-mi:"MI:0030"(cross-linking study) Tang et al. (2019) imex:IM-28478|pubmed:31412244 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-26443127|imex:IM-28478-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:XP_011543165.1|ensembl:ENSP00000366475|ensembl:ENST00000421419|ensembl:ENSP00000410522|refseq:NP_055919.2|ensembl:ENSG00000110046(gene)|ensembl:ENST00000377264(transcript)|go:"GO:0000045"(autophagosome assembly)|go:"GO:0000407"(phagophore assembly site)|go:"GO:0000422"(autophagy of mitochondrion)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005811"(lipid droplet)|go:"GO:0019898"(extrinsic component of membrane)|go:"GO:0032266"(phosphatidylinositol-3-phosphate binding)|go:"GO:0034045"(phagophore assembly site membrane)|go:"GO:0034727"(piecemeal microautophagy of the nucleus)|go:"GO:0044805"(late nucleophagy)|interpro:IPR015412(ATG2, C-terminal)|interpro:IPR026849|interpro:IPR026854|rcsb pdb:6KLR|go:"GO:0061709"(reticulophagy) refseq:XP_005244996.1|interpro:IPR008662(Lamina-associated polypeptide 1C)|ensembl:ENSG00000169905(gene)|ensembl:ENST00000367612(transcript)|ensembl:ENST00000609928(transcript)|go:"GO:0001671"(ATPase activator activity)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0007029"(endoplasmic reticulum organization)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0031965"(nuclear membrane)|go:"GO:0032781"(positive regulation of ATP-dependent activity)|go:"GO:0051117"(ATPase binding)|go:"GO:0061024"(membrane organization)|go:"GO:0090435"(protein localization to nuclear envelope)|refseq:XP_016855963.1|refseq:XP_016855964.1|refseq:NP_001186189.1|refseq:NP_659471.1|interpro:IPR038599|rcsb pdb:5J1S|rcsb pdb:5J1T - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/10/21 2020/11/06 rogid:RC80jQqKw4ekVFudqz/IunWCEMA9606 rogid:HjY3sLjzR1jmKq2EqIKRvY3GxKc9606 rigid:319IsGV1oRp3OLZk5khzgtmEExU false enhanced green fluorescent protein tag:n-n|sufficient binding region:1776-1820 - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q2TAZ0 uniprotkb:O75844 intact:EBI-2514077|intact:EBI-28978291|uniprotkb:Q8TAI8|uniprotkb:O43154|uniprotkb:Q14DM2|uniprotkb:Q7Z6K8|uniprotkb:Q6ZTV2|uniprotkb:Q96HH7|uniprotkb:Q8IVY5|ensembl:ENSP00000366475 intact:EBI-1056377|uniprotkb:Q8NDZ8|uniprotkb:Q9UBQ2|uniprotkb:B3KQI7|uniprotkb:D3DPU7|ensembl:ENSP00000361845 psi-mi:atg2a_human(display_long)|uniprotkb:ATG2A(gene name)|psi-mi:ATG2A(display_short)|uniprotkb:KIAA0404(gene name synonym) psi-mi:face1_human(display_long)|uniprotkb:ZMPSTE24(gene name)|psi-mi:ZMPSTE24(display_short)|uniprotkb:FACE1(gene name synonym)|uniprotkb:STE24(gene name synonym)|uniprotkb:Prenyl protein-specific endoprotease 1(gene name synonym)|uniprotkb:Farnesylated proteins-converting enzyme 1(gene name synonym)|uniprotkb:Zinc metalloproteinase Ste24 homolog(gene name synonym) psi-mi:"MI:0030"(cross-linking study) Tang et al. (2019) imex:IM-28478|pubmed:31412244 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-26443127|imex:IM-28478-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:XP_011543165.1|ensembl:ENSP00000366475|ensembl:ENST00000421419|ensembl:ENSP00000410522|refseq:NP_055919.2|ensembl:ENSG00000110046(gene)|ensembl:ENST00000377264(transcript)|go:"GO:0000045"(autophagosome assembly)|go:"GO:0000407"(phagophore assembly site)|go:"GO:0000422"(autophagy of mitochondrion)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005811"(lipid droplet)|go:"GO:0019898"(extrinsic component of membrane)|go:"GO:0032266"(phosphatidylinositol-3-phosphate binding)|go:"GO:0034045"(phagophore assembly site membrane)|go:"GO:0034727"(piecemeal microautophagy of the nucleus)|go:"GO:0044805"(late nucleophagy)|interpro:IPR015412(ATG2, C-terminal)|interpro:IPR026849|interpro:IPR026854|rcsb pdb:6KLR|go:"GO:0061709"(reticulophagy) refseq:NP_005848.2|ensembl:ENSG00000084073(gene)|ensembl:ENST00000372759(transcript)|go:"GO:0001889"(liver development)|go:"GO:0001942"(hair follicle development)|go:"GO:0003007"(heart morphogenesis)|go:"GO:0003229"(ventricular cardiac muscle tissue development)|go:"GO:0003231"(cardiac ventricle development)|go:"GO:0003417"(growth plate cartilage development)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0005637"(nuclear inner membrane)|go:"GO:0006281"(DNA repair)|go:"GO:0006508"(proteolysis)|go:"GO:0006925"(inflammatory cell apoptotic process)|go:"GO:0004222"(metalloendopeptidase activity)|go:"GO:0006998"(nuclear envelope organization)|go:"GO:0007628"(adult walking behavior)|go:"GO:0008235"(metalloexopeptidase activity)|go:"GO:0008340"(determination of adult lifespan)|go:"GO:0008360"(regulation of cell shape)|go:"GO:0010506"(regulation of autophagy)|go:"GO:0010906"(regulation of glucose metabolic process)|go:"GO:0016020"(membrane)|go:"GO:0019216"(regulation of lipid metabolic process)|go:"GO:0030176"(integral component of endoplasmic reticulum membrane)|go:"GO:0030282"(bone mineralization)|go:"GO:0030327"(prenylated protein catabolic process)|go:"GO:0030500"(regulation of bone mineralization)|go:"GO:0032006"(regulation of TOR signaling)|go:"GO:0032350"(regulation of hormone metabolic process)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035264"(multicellular organism growth)|go:"GO:0040014"(regulation of multicellular organism growth)|go:"GO:0043007"(maintenance of rDNA)|go:"GO:0043516"(regulation of DNA damage response, signal transduction by p53 class mediator)|go:"GO:0043979"(histone H2B-K5 acetylation)|go:"GO:0044029"(hypomethylation of CpG island)|go:"GO:0044255"(cellular lipid metabolic process)|go:"GO:0046872"(metal ion binding)|go:"GO:0048145"(regulation of fibroblast proliferation)|go:"GO:0048538"(thymus development)|go:"GO:0050688"(regulation of defense response to virus)|go:"GO:0050905"(neuromuscular process)|go:"GO:0055013"(cardiac muscle cell development)|go:"GO:0060307"(regulation of ventricular cardiac muscle cell membrane repolarization)|go:"GO:0060993"(kidney morphogenesis)|go:"GO:0061337"(cardiac conduction)|go:"GO:0061762"(CAMKK-AMPK signaling cascade)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070302"(regulation of stress-activated protein kinase signaling cascade)|go:"GO:0071480"(cellular response to gamma radiation)|go:"GO:0071586"(CAAX-box protein processing)|go:"GO:0072423"(response to DNA damage checkpoint signaling)|go:"GO:1903025"(regulation of RNA polymerase II regulatory region sequence-specific DNA binding)|go:"GO:1903463"(regulation of mitotic cell cycle DNA replication)|go:"GO:1903799"(negative regulation of production of miRNAs involved in gene silencing by miRNA)|go:"GO:1990036"(calcium ion import into sarcoplasmic reticulum)|go:"GO:1990164"(histone H2A phosphorylation)|go:"GO:2000618"(regulation of histone H4-K16 acetylation)|go:"GO:2000730"(regulation of termination of RNA polymerase I transcription)|go:"GO:2000772"(regulation of cellular senescence)|interpro:IPR001915(Peptidase M48, Ste24p)|interpro:IPR027057|interpro:IPR032456|rcsb pdb:2YPT|rcsb pdb:4AW6|rcsb pdb:5SYT|rcsb pdb:6BH8|dip:DIP-39641N - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/10/21 2020/11/06 rogid:RC80jQqKw4ekVFudqz/IunWCEMA9606 rogid:OPwBYiVhnltoUrmk2Jtj07QDSCg9606 rigid:319IsGV1oRp3OLZk5khzgtmEExU false enhanced green fluorescent protein tag:n-n|sufficient binding region:1776-1820 - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q2TAZ0 uniprotkb:Q92667 intact:EBI-2514077|intact:EBI-28978291|uniprotkb:Q8TAI8|uniprotkb:O43154|uniprotkb:Q14DM2|uniprotkb:Q7Z6K8|uniprotkb:Q6ZTV2|uniprotkb:Q96HH7|uniprotkb:Q8IVY5|ensembl:ENSP00000366475 intact:EBI-2119593|uniprotkb:Q13320|uniprotkb:Q9BW14|uniprotkb:A8K8Q1|uniprotkb:D3DTZ0|ensembl:ENSP00000337736|ensembl:ENSP00000443139|ensembl:ENSP00000459895|ensembl:ENSP00000459968|ensembl:ENSP00000478212 psi-mi:atg2a_human(display_long)|uniprotkb:ATG2A(gene name)|psi-mi:ATG2A(display_short)|uniprotkb:KIAA0404(gene name synonym) psi-mi:akap1_human(display_long)|uniprotkb:AKAP1(gene name)|psi-mi:AKAP1(display_short)|uniprotkb:AKAP149(gene name synonym)|uniprotkb:PRKA1(gene name synonym)|uniprotkb:Protein kinase A-anchoring protein 1(gene name synonym)|uniprotkb:A-kinase anchor protein 149 kDa(gene name synonym)|uniprotkb:Dual specificity A-kinase-anchoring protein 1(gene name synonym)|uniprotkb:Spermatid A-kinase anchor protein 84(gene name synonym) psi-mi:"MI:0030"(cross-linking study) Tang et al. (2019) imex:IM-28478|pubmed:31412244 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-26443127|imex:IM-28478-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:XP_011543165.1|ensembl:ENSP00000366475|ensembl:ENST00000421419|ensembl:ENSP00000410522|refseq:NP_055919.2|ensembl:ENSG00000110046(gene)|ensembl:ENST00000377264(transcript)|go:"GO:0000045"(autophagosome assembly)|go:"GO:0000407"(phagophore assembly site)|go:"GO:0000422"(autophagy of mitochondrion)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005811"(lipid droplet)|go:"GO:0019898"(extrinsic component of membrane)|go:"GO:0032266"(phosphatidylinositol-3-phosphate binding)|go:"GO:0034045"(phagophore assembly site membrane)|go:"GO:0034727"(piecemeal microautophagy of the nucleus)|go:"GO:0044805"(late nucleophagy)|interpro:IPR015412(ATG2, C-terminal)|interpro:IPR026849|interpro:IPR026854|rcsb pdb:6KLR|go:"GO:0061709"(reticulophagy) refseq:XP_016880678.1|refseq:XP_016880679.1|refseq:XP_016880680.1|refseq:NP_001229831.1|refseq:NP_001229832.1|refseq:NP_003479.1|refseq:XP_005257764.1|refseq:XP_005257766.1|ensembl:ENSG00000121057(gene)|ensembl:ENST00000337714(transcript)|ensembl:ENST00000539273(transcript)|ensembl:ENST00000571629(transcript)|ensembl:ENST00000572557(transcript)|ensembl:ENST00000621116(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0005739"(mitochondrion)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005829"(cytosol)|go:"GO:0006915"(apoptotic process)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0034237"(protein kinase A regulatory subunit binding)|go:"GO:0140374"(antiviral innate immune response)|interpro:IPR002999(Tudor)|interpro:IPR004087(K Homology)|interpro:IPR004088(K Homology, type 1)|interpro:IPR035437|interpro:IPR036612|mint:Q92667|reactome:R-HSA-8949215|reactome:R-HSA-983231 - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/10/21 2020/11/06 rogid:RC80jQqKw4ekVFudqz/IunWCEMA9606 rogid:8HzwuoBdBWw+LZKg6WpYxMKnfYE9606 rigid:319IsGV1oRp3OLZk5khzgtmEExU false enhanced green fluorescent protein tag:n-n|sufficient binding region:1776-1820 - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q2TAZ0 uniprotkb:Q86XL3 intact:EBI-2514077|intact:EBI-28978291|uniprotkb:Q8TAI8|uniprotkb:O43154|uniprotkb:Q14DM2|uniprotkb:Q7Z6K8|uniprotkb:Q6ZTV2|uniprotkb:Q96HH7|uniprotkb:Q8IVY5|ensembl:ENSP00000366475 intact:EBI-1773621|uniprotkb:O75176|uniprotkb:Q6P6A5|uniprotkb:Q96DH4|uniprotkb:Q8TAZ9|uniprotkb:A8KAG3|uniprotkb:B3KN97|uniprotkb:B3KSF8|ensembl:ENSP00000350686 psi-mi:atg2a_human(display_long)|uniprotkb:ATG2A(gene name)|psi-mi:ATG2A(display_short)|uniprotkb:KIAA0404(gene name synonym) psi-mi:ankl2_human(display_long)|uniprotkb:ANKLE2(gene name)|psi-mi:ANKLE2(display_short)|uniprotkb:KIAA0692(gene name synonym)|uniprotkb:LEM domain-containing protein 4(gene name synonym)|uniprotkb:LEM4(gene name synonym) psi-mi:"MI:0030"(cross-linking study) Tang et al. (2019) imex:IM-28478|pubmed:31412244 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-26443127|imex:IM-28478-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:XP_011543165.1|ensembl:ENSP00000366475|ensembl:ENST00000421419|ensembl:ENSP00000410522|refseq:NP_055919.2|ensembl:ENSG00000110046(gene)|ensembl:ENST00000377264(transcript)|go:"GO:0000045"(autophagosome assembly)|go:"GO:0000407"(phagophore assembly site)|go:"GO:0000422"(autophagy of mitochondrion)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005811"(lipid droplet)|go:"GO:0019898"(extrinsic component of membrane)|go:"GO:0032266"(phosphatidylinositol-3-phosphate binding)|go:"GO:0034045"(phagophore assembly site membrane)|go:"GO:0034727"(piecemeal microautophagy of the nucleus)|go:"GO:0044805"(late nucleophagy)|interpro:IPR015412(ATG2, C-terminal)|interpro:IPR026849|interpro:IPR026854|rcsb pdb:6KLR|go:"GO:0061709"(reticulophagy) refseq:XP_011533089.1|refseq:XP_011533090.1|refseq:NP_055929.1|ensembl:ENSG00000176915(gene)|ensembl:ENST00000357997(transcript)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0007084"(mitotic nuclear membrane reassembly)|go:"GO:0007417"(central nervous system development)|go:"GO:0016020"(membrane)|go:"GO:0019888"(protein phosphatase regulator activity)|go:"GO:0030176"(integral component of endoplasmic reticulum membrane)|go:"GO:0035307"(positive regulation of protein dephosphorylation)|go:"GO:0042326"(negative regulation of phosphorylation)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0050790"(regulation of catalytic activity)|go:"GO:0051301"(cell division)|go:"GO:0051721"(protein phosphatase 2A binding)|interpro:IPR003887(Lamino-associated polypeptide 2/emerin)|interpro:IPR011015(LEM-like fold)|interpro:IPR011320(Ribonuclease HI, N-terminal)|interpro:IPR035006|interpro:IPR035007|interpro:IPR036770|interpro:IPR037056|reactome:R-HSA-2995383|reactome:R-HSA-9013404|reactome:R-HSA-9013408 - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/10/21 2020/11/06 rogid:RC80jQqKw4ekVFudqz/IunWCEMA9606 rogid:Gaa+XAC6xNVobxZhMlzCHvVDFgk9606 rigid:319IsGV1oRp3OLZk5khzgtmEExU false enhanced green fluorescent protein tag:n-n|sufficient binding region:1776-1820 - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q2TAZ0 uniprotkb:Q9NX63 intact:EBI-2514077|intact:EBI-28978291|uniprotkb:Q8TAI8|uniprotkb:O43154|uniprotkb:Q14DM2|uniprotkb:Q7Z6K8|uniprotkb:Q6ZTV2|uniprotkb:Q96HH7|uniprotkb:Q8IVY5|ensembl:ENSP00000366475 intact:EBI-743375|ensembl:ENSP00000262570 psi-mi:atg2a_human(display_long)|uniprotkb:ATG2A(gene name)|psi-mi:ATG2A(display_short)|uniprotkb:KIAA0404(gene name synonym) psi-mi:mic19_human(display_long)|uniprotkb:CHCHD3(gene name)|psi-mi:CHCHD3(display_short)|uniprotkb:MINOS3(gene name synonym)|uniprotkb:Coiled-coil-helix-coiled-coil-helix domain-containing protein 3(gene name synonym)|uniprotkb:MIC19(gene name synonym) psi-mi:"MI:0030"(cross-linking study) Tang et al. (2019) imex:IM-28478|pubmed:31412244 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-26443127|imex:IM-28478-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:XP_011543165.1|ensembl:ENSP00000366475|ensembl:ENST00000421419|ensembl:ENSP00000410522|refseq:NP_055919.2|ensembl:ENSG00000110046(gene)|ensembl:ENST00000377264(transcript)|go:"GO:0000045"(autophagosome assembly)|go:"GO:0000407"(phagophore assembly site)|go:"GO:0000422"(autophagy of mitochondrion)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005811"(lipid droplet)|go:"GO:0019898"(extrinsic component of membrane)|go:"GO:0032266"(phosphatidylinositol-3-phosphate binding)|go:"GO:0034045"(phagophore assembly site membrane)|go:"GO:0034727"(piecemeal microautophagy of the nucleus)|go:"GO:0044805"(late nucleophagy)|interpro:IPR015412(ATG2, C-terminal)|interpro:IPR026849|interpro:IPR026854|rcsb pdb:6KLR|go:"GO:0061709"(reticulophagy) go:"GO:0008053"(mitochondrial fusion)|refseq:NP_060282.1|refseq:NP_001304106.1|ensembl:ENSG00000106554(gene)|ensembl:ENST00000262570(transcript)|go:"GO:0001401"(SAM complex)|go:"GO:0005634"(nucleus)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0007007"(inner mitochondrial membrane organization)|go:"GO:0042407"(cristae formation)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0061617"(MICOS complex)|go:"GO:0070062"(extracellular exosome)|go:"GO:0140275"(MIB complex)|mint:Q9NX63|reactome:R-HSA-1268020|reactome:R-HSA-8949613|go:"GO:0019902"(phosphatase binding) - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/10/21 2020/11/06 rogid:RC80jQqKw4ekVFudqz/IunWCEMA9606 rogid:Ox0+PoTPYwxw8cKNqpzvSCg+Smg9606 rigid:319IsGV1oRp3OLZk5khzgtmEExU false enhanced green fluorescent protein tag:n-n|sufficient binding region:1776-1820 - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q2TAZ0 uniprotkb:Q9BTV4 intact:EBI-2514077|intact:EBI-28978291|uniprotkb:Q8TAI8|uniprotkb:O43154|uniprotkb:Q14DM2|uniprotkb:Q7Z6K8|uniprotkb:Q6ZTV2|uniprotkb:Q96HH7|uniprotkb:Q8IVY5|ensembl:ENSP00000366475 intact:EBI-721293|uniprotkb:Q7L4N5|uniprotkb:Q8NC30|uniprotkb:Q96A63|uniprotkb:Q96F19|uniprotkb:Q96JX0|uniprotkb:Q9H076|ensembl:ENSP00000303992 psi-mi:atg2a_human(display_long)|uniprotkb:ATG2A(gene name)|psi-mi:ATG2A(display_short)|uniprotkb:KIAA0404(gene name synonym) psi-mi:tmm43_human(display_long)|uniprotkb:TMEM43(gene name)|psi-mi:TMEM43(display_short)|uniprotkb:UNQ2564/PRO6244(orf name)|uniprotkb:Protein LUMA(gene name synonym) psi-mi:"MI:0030"(cross-linking study) Tang et al. (2019) imex:IM-28478|pubmed:31412244 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-26443127|imex:IM-28478-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:XP_011543165.1|ensembl:ENSP00000366475|ensembl:ENST00000421419|ensembl:ENSP00000410522|refseq:NP_055919.2|ensembl:ENSG00000110046(gene)|ensembl:ENST00000377264(transcript)|go:"GO:0000045"(autophagosome assembly)|go:"GO:0000407"(phagophore assembly site)|go:"GO:0000422"(autophagy of mitochondrion)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005811"(lipid droplet)|go:"GO:0019898"(extrinsic component of membrane)|go:"GO:0032266"(phosphatidylinositol-3-phosphate binding)|go:"GO:0034045"(phagophore assembly site membrane)|go:"GO:0034727"(piecemeal microautophagy of the nucleus)|go:"GO:0044805"(late nucleophagy)|interpro:IPR015412(ATG2, C-terminal)|interpro:IPR026849|interpro:IPR026854|rcsb pdb:6KLR|go:"GO:0061709"(reticulophagy) refseq:NP_077310.1|ensembl:ENSG00000170876(gene)|ensembl:ENST00000306077(transcript)|go:"GO:0005639"(integral component of nuclear inner membrane)|go:"GO:0005788"(endoplasmic reticulum lumen)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0042802"(identical protein binding)|go:"GO:0043621"(protein self-association)|go:"GO:0071763"(nuclear membrane organization)|interpro:IPR012430(Protein of unknown function DUF1625) - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/10/21 2020/11/06 rogid:RC80jQqKw4ekVFudqz/IunWCEMA9606 rogid:8VCyVNtrzh7J9uJ2EjQLBhJGrfc9606 rigid:319IsGV1oRp3OLZk5khzgtmEExU false enhanced green fluorescent protein tag:n-n|sufficient binding region:1776-1820 - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q2TAZ0 uniprotkb:Q15042 intact:EBI-2514077|intact:EBI-28978291|uniprotkb:Q8TAI8|uniprotkb:O43154|uniprotkb:Q14DM2|uniprotkb:Q7Z6K8|uniprotkb:Q6ZTV2|uniprotkb:Q96HH7|uniprotkb:Q8IVY5|ensembl:ENSP00000366475 intact:EBI-1053078|uniprotkb:Q659F5|uniprotkb:Q8TBB4|uniprotkb:C9J837|ensembl:ENSP00000264158|uniprotkb:A6H8Z3 psi-mi:atg2a_human(display_long)|uniprotkb:ATG2A(gene name)|psi-mi:ATG2A(display_short)|uniprotkb:KIAA0404(gene name synonym) psi-mi:rb3gp_human(display_long)|uniprotkb:RAB3 GTPase-activating protein 130 kDa subunit(gene name synonym)|uniprotkb:Rab3-GAP p130(gene name synonym)|uniprotkb:RAB3GAP1(gene name)|psi-mi:RAB3GAP1(display_short)|uniprotkb:KIAA0066(gene name synonym)|uniprotkb:RAB3GAP(gene name synonym) psi-mi:"MI:0030"(cross-linking study) Tang et al. (2019) imex:IM-28478|pubmed:31412244 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-26443127|imex:IM-28478-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:XP_011543165.1|ensembl:ENSP00000366475|ensembl:ENST00000421419|ensembl:ENSP00000410522|refseq:NP_055919.2|ensembl:ENSG00000110046(gene)|ensembl:ENST00000377264(transcript)|go:"GO:0000045"(autophagosome assembly)|go:"GO:0000407"(phagophore assembly site)|go:"GO:0000422"(autophagy of mitochondrion)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005811"(lipid droplet)|go:"GO:0019898"(extrinsic component of membrane)|go:"GO:0032266"(phosphatidylinositol-3-phosphate binding)|go:"GO:0034045"(phagophore assembly site membrane)|go:"GO:0034727"(piecemeal microautophagy of the nucleus)|go:"GO:0044805"(late nucleophagy)|interpro:IPR015412(ATG2, C-terminal)|interpro:IPR026849|interpro:IPR026854|rcsb pdb:6KLR|go:"GO:0061709"(reticulophagy) refseq:NP_036365.1|ensembl:ENSG00000115839(gene)|ensembl:ENST00000264158(transcript)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005811"(lipid droplet)|go:"GO:0005829"(cytosol)|go:"GO:0007420"(brain development)|go:"GO:0021854"(hypothalamus development)|go:"GO:0031267"(small GTPase binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034389"(lipid droplet organization)|go:"GO:0043010"(camera-type eye development)|go:"GO:0043087"(regulation of GTPase activity)|go:"GO:0043547"(positive regulation of GTPase activity)|go:"GO:0048172"(regulation of short-term neuronal synaptic plasticity)|go:"GO:0060079"(excitatory postsynaptic potential)|go:"GO:0060325"(face morphogenesis)|go:"GO:0061646"(positive regulation of glutamate neurotransmitter secretion in response to membrane depolarization)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071782"(endoplasmic reticulum tubular network)|go:"GO:0097051"(establishment of protein localization to endoplasmic reticulum membrane)|go:"GO:0098794"(postsynapse)|go:"GO:1903061"(positive regulation of protein lipidation)|go:"GO:1903233"(regulation of calcium ion-dependent exocytosis of neurotransmitter)|go:"GO:1903373"(positive regulation of endoplasmic reticulum tubular network organization)|go:"GO:2000786"(positive regulation of autophagosome assembly)|interpro:IPR026147|reactome:R-HSA-6811436|reactome:R-HSA-8876198|refseq:NP_001165906.1 - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/10/21 2020/11/06 rogid:RC80jQqKw4ekVFudqz/IunWCEMA9606 rogid:JCtnJX01timbIenQexwG84yBu2I9606 rigid:319IsGV1oRp3OLZk5khzgtmEExU false enhanced green fluorescent protein tag:n-n|sufficient binding region:1776-1820 - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q2TAZ0 uniprotkb:Q9Y512 intact:EBI-2514077|intact:EBI-28978291|uniprotkb:Q8TAI8|uniprotkb:O43154|uniprotkb:Q14DM2|uniprotkb:Q7Z6K8|uniprotkb:Q6ZTV2|uniprotkb:Q96HH7|uniprotkb:Q8IVY5|ensembl:ENSP00000366475 intact:EBI-748409|uniprotkb:Q969Y9|uniprotkb:Q96I46|uniprotkb:Q9NW85|uniprotkb:Q9UQM9|ensembl:ENSP00000345445|uniprotkb:Q53HC4|uniprotkb:Q56VW7 psi-mi:atg2a_human(display_long)|uniprotkb:ATG2A(gene name)|psi-mi:ATG2A(display_short)|uniprotkb:KIAA0404(gene name synonym) psi-mi:sam50_human(display_long)|uniprotkb:SAMM50(gene name)|psi-mi:SAMM50(display_short)|uniprotkb:CGI-51(orf name)|uniprotkb:Transformation-related gene 3 protein(gene name synonym)|uniprotkb:TRG3(orf name)|uniprotkb:SAM50(gene name synonym) psi-mi:"MI:0030"(cross-linking study) Tang et al. (2019) imex:IM-28478|pubmed:31412244 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-26443127|imex:IM-28478-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:XP_011543165.1|ensembl:ENSP00000366475|ensembl:ENST00000421419|ensembl:ENSP00000410522|refseq:NP_055919.2|ensembl:ENSG00000110046(gene)|ensembl:ENST00000377264(transcript)|go:"GO:0000045"(autophagosome assembly)|go:"GO:0000407"(phagophore assembly site)|go:"GO:0000422"(autophagy of mitochondrion)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005811"(lipid droplet)|go:"GO:0019898"(extrinsic component of membrane)|go:"GO:0032266"(phosphatidylinositol-3-phosphate binding)|go:"GO:0034045"(phagophore assembly site membrane)|go:"GO:0034727"(piecemeal microautophagy of the nucleus)|go:"GO:0044805"(late nucleophagy)|interpro:IPR015412(ATG2, C-terminal)|interpro:IPR026849|interpro:IPR026854|rcsb pdb:6KLR|go:"GO:0061709"(reticulophagy) ensembl:ENSG00000100347(gene)|refseq:NP_056195.3|ensembl:ENST00000350028(transcript)|go:"GO:0001401"(SAM complex)|go:"GO:0005739"(mitochondrion)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0007007"(inner mitochondrial membrane organization)|go:"GO:0016021"(integral component of membrane)|go:"GO:0033108"(mitochondrial respiratory chain complex assembly)|go:"GO:0034622"|go:"GO:0042407"(cristae formation)|go:"GO:0045040"(protein insertion into mitochondrial outer membrane)|go:"GO:0070062"(extracellular exosome)|go:"GO:0140275"(MIB complex)|interpro:IPR000184("Bacterial surface antigen (D15)")|interpro:IPR034746|interpro:IPR039910|mint:Q9Y512|rcsb pdb:6YOO|rcsb pdb:6YOP|reactome:R-HSA-1268020|reactome:R-HSA-8949613|reactome:R-HSA-9013404 - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/10/21 2020/11/06 rogid:RC80jQqKw4ekVFudqz/IunWCEMA9606 rogid:wpqEL4ia/LUNdXSlQBRZxPfwCcY9606 rigid:319IsGV1oRp3OLZk5khzgtmEExU false enhanced green fluorescent protein tag:n-n|sufficient binding region:1776-1820 - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q2TAZ0 uniprotkb:Q96CS3 intact:EBI-2514077|intact:EBI-28978291|uniprotkb:Q8TAI8|uniprotkb:O43154|uniprotkb:Q14DM2|uniprotkb:Q7Z6K8|uniprotkb:Q6ZTV2|uniprotkb:Q96HH7|uniprotkb:Q8IVY5|ensembl:ENSP00000366475 intact:EBI-1055805|uniprotkb:O94963|uniprotkb:Q8IUF2|uniprotkb:Q9BRP2|uniprotkb:Q9BVM7|ensembl:ENSP00000261942 psi-mi:atg2a_human(display_long)|uniprotkb:ATG2A(gene name)|psi-mi:ATG2A(display_short)|uniprotkb:KIAA0404(gene name synonym) psi-mi:faf2_human(display_long)|uniprotkb:Protein ETEA(gene name synonym)|uniprotkb:FAF2(gene name)|psi-mi:FAF2(display_short)|uniprotkb:ETEA(gene name synonym)|uniprotkb:KIAA0887(gene name synonym)|uniprotkb:UBXD8(gene name synonym)|uniprotkb:UBXN3B(gene name synonym)|uniprotkb:UBX domain-containing protein 3B(gene name synonym)|uniprotkb:UBX domain-containing protein 8(gene name synonym) psi-mi:"MI:0030"(cross-linking study) Tang et al. (2019) imex:IM-28478|pubmed:31412244 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-26443127|imex:IM-28478-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:XP_011543165.1|ensembl:ENSP00000366475|ensembl:ENST00000421419|ensembl:ENSP00000410522|refseq:NP_055919.2|ensembl:ENSG00000110046(gene)|ensembl:ENST00000377264(transcript)|go:"GO:0000045"(autophagosome assembly)|go:"GO:0000407"(phagophore assembly site)|go:"GO:0000422"(autophagy of mitochondrion)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005811"(lipid droplet)|go:"GO:0019898"(extrinsic component of membrane)|go:"GO:0032266"(phosphatidylinositol-3-phosphate binding)|go:"GO:0034045"(phagophore assembly site membrane)|go:"GO:0034727"(piecemeal microautophagy of the nucleus)|go:"GO:0044805"(late nucleophagy)|interpro:IPR015412(ATG2, C-terminal)|interpro:IPR026849|interpro:IPR026854|rcsb pdb:6KLR|go:"GO:0061709"(reticulophagy) refseq:NP_055428.1|ensembl:ENSP00000261942|ensembl:ENST00000261942(transcript)|go:"GO:0005576"(extracellular region)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005811"(lipid droplet)|go:"GO:0006986"(response to unfolded protein)|go:"GO:0030433"(ubiquitin-dependent ERAD pathway)|go:"GO:0030970"(retrograde protein transport, ER to cytosol)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0034098"(VCP-NPL4-UFD1 AAA ATPase complex)|go:"GO:0034389"(lipid droplet organization)|go:"GO:0035473"(lipase binding)|go:"GO:0035578"(azurophil granule lumen)|go:"GO:0043130"(ubiquitin binding)|go:"GO:0055102"(lipase inhibitor activity)|interpro:IPR001012(UBX)|interpro:IPR006577(UAS)|interpro:IPR009060(UBA-like)|interpro:IPR029071|interpro:IPR036249|mint:Q96CS3|rcsb pdb:2DAM|reactome:R-HSA-6798695|reactome:R-HSA-8980692|ensembl:ENSG00000113194(gene)|dip:DIP-46261N - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/10/21 2020/11/06 rogid:RC80jQqKw4ekVFudqz/IunWCEMA9606 rogid:GCm7BqDpwxDW1iABu0cShmWHtZQ9606 rigid:319IsGV1oRp3OLZk5khzgtmEExU false enhanced green fluorescent protein tag:n-n|sufficient binding region:1776-1820 - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q2TAZ0 uniprotkb:P51648 intact:EBI-2514077|intact:EBI-28978291|uniprotkb:Q8TAI8|uniprotkb:O43154|uniprotkb:Q14DM2|uniprotkb:Q7Z6K8|uniprotkb:Q6ZTV2|uniprotkb:Q96HH7|uniprotkb:Q8IVY5|ensembl:ENSP00000366475 intact:EBI-1391128|uniprotkb:Q93011|uniprotkb:Q96J37|uniprotkb:Q6I9T3|ensembl:ENSP00000176643|ensembl:ENSP00000461916|ensembl:ENSP00000463637|ensembl:ENSP00000500092 psi-mi:atg2a_human(display_long)|uniprotkb:ATG2A(gene name)|psi-mi:ATG2A(display_short)|uniprotkb:KIAA0404(gene name synonym) psi-mi:al3a2_human(display_long)|uniprotkb:Aldehyde dehydrogenase 10(gene name synonym)|uniprotkb:Microsomal aldehyde dehydrogenase(gene name synonym)|uniprotkb:ALDH3A2(gene name)|psi-mi:ALDH3A2(display_short)|uniprotkb:ALDH10(gene name synonym)|uniprotkb:FALDH(gene name synonym)|uniprotkb:Fatty aldehyde dehydrogenase(gene name synonym) psi-mi:"MI:0030"(cross-linking study) Tang et al. (2019) imex:IM-28478|pubmed:31412244 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-26443127|imex:IM-28478-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:XP_011543165.1|ensembl:ENSP00000366475|ensembl:ENST00000421419|ensembl:ENSP00000410522|refseq:NP_055919.2|ensembl:ENSG00000110046(gene)|ensembl:ENST00000377264(transcript)|go:"GO:0000045"(autophagosome assembly)|go:"GO:0000407"(phagophore assembly site)|go:"GO:0000422"(autophagy of mitochondrion)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005811"(lipid droplet)|go:"GO:0019898"(extrinsic component of membrane)|go:"GO:0032266"(phosphatidylinositol-3-phosphate binding)|go:"GO:0034045"(phagophore assembly site membrane)|go:"GO:0034727"(piecemeal microautophagy of the nucleus)|go:"GO:0044805"(late nucleophagy)|interpro:IPR015412(ATG2, C-terminal)|interpro:IPR026849|interpro:IPR026854|rcsb pdb:6KLR|go:"GO:0061709"(reticulophagy) refseq:NP_000373.1|refseq:NP_001026976.1|refseq:XP_011522034.1|refseq:XP_011522035.1|refseq:XP_016879845.1|refseq:XP_016879846.1|ensembl:ENST00000672357(transcript)|go:"GO:0004028"(3-chloroallyl aldehyde dehydrogenase activity)|go:"GO:0004029"("aldehyde dehydrogenase (NAD+) activity")|go:"GO:0005777"(peroxisome)|go:"GO:0005778"(peroxisomal membrane)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005829"(cytosol)|go:"GO:0006081"(cellular aldehyde metabolic process)|go:"GO:0006631"(fatty acid metabolic process)|go:"GO:0006714"(sesquiterpenoid metabolic process)|go:"GO:0007417"(central nervous system development)|go:"GO:0007422"(peripheral nervous system development)|go:"GO:0008544"(epidermis development)|go:"GO:0016021"(integral component of membrane)|go:"GO:0033306"(phytol metabolic process)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0043878"("glyceraldehyde-3-phosphate dehydrogenase (NAD+) (non-phosphorylating) activity")|go:"GO:0046458"(hexadecanal metabolic process)|go:"GO:0046577"(long-chain-alcohol oxidase activity)|go:"GO:0050061"(long-chain-aldehyde dehydrogenase activity)|go:"GO:0052814"(medium-chain-aldehyde dehydrogenase activity)|interpro:IPR012394("Aldehyde dehydrogenase NAD(P)-dependent")|interpro:IPR015590(Aldehyde dehydrogenase)|interpro:IPR016160(Aldehyde dehydrogenase, conserved site)|interpro:IPR016161(Aldehyde/histidinol dehydrogenase)|interpro:IPR016162(Aldehyde dehydrogenase, N-terminal)|interpro:IPR016163(Aldehyde dehydrogenase, C-terminal)|interpro:IPR029510|mint:P51648|rcsb pdb:4QGK|reactome:R-HSA-1660661|reactome:R-HSA-389599|reactome:R-HSA-9603798|reactome:R-HSA-9609523|reactome:R-HSA-9696270|reactome:R-HSA-9696273|ensembl:ENSG00000072210(gene)|ensembl:ENST00000176643(transcript)|ensembl:ENST00000579855(transcript)|ensembl:ENST00000581518(transcript) - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/10/21 2020/11/06 rogid:RC80jQqKw4ekVFudqz/IunWCEMA9606 rogid:ADi5/NMf5JsjzaonzFIbHZebIlQ9606 rigid:319IsGV1oRp3OLZk5khzgtmEExU false enhanced green fluorescent protein tag:n-n|sufficient binding region:1776-1820 - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q2TAZ0 uniprotkb:Q8TBA6 intact:EBI-2514077|intact:EBI-28978291|uniprotkb:Q8TAI8|uniprotkb:O43154|uniprotkb:Q14DM2|uniprotkb:Q7Z6K8|uniprotkb:Q6ZTV2|uniprotkb:Q96HH7|uniprotkb:Q8IVY5|ensembl:ENSP00000366475 intact:EBI-11278147|uniprotkb:O95287|uniprotkb:Q03962|uniprotkb:Q2TS49|uniprotkb:Q9UQQ7|uniprotkb:C9JRU1|ensembl:ENSP00000163416 psi-mi:atg2a_human(display_long)|uniprotkb:ATG2A(gene name)|psi-mi:ATG2A(display_short)|uniprotkb:KIAA0404(gene name synonym) psi-mi:goga5_human(display_long)|uniprotkb:GOLGA5(gene name)|psi-mi:GOLGA5(display_short)|uniprotkb:Cell proliferation-inducing gene 31 protein(gene name synonym)|uniprotkb:Golgin-84(gene name synonym)|uniprotkb:Protein Ret-II(gene name synonym)|uniprotkb:RET-fused gene 5 protein(gene name synonym)|uniprotkb:RETII(gene name synonym)|uniprotkb:RFG5(gene name synonym)|uniprotkb:PIG31(orf name) psi-mi:"MI:0030"(cross-linking study) Tang et al. (2019) imex:IM-28478|pubmed:31412244 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-26443127|imex:IM-28478-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:XP_011543165.1|ensembl:ENSP00000366475|ensembl:ENST00000421419|ensembl:ENSP00000410522|refseq:NP_055919.2|ensembl:ENSG00000110046(gene)|ensembl:ENST00000377264(transcript)|go:"GO:0000045"(autophagosome assembly)|go:"GO:0000407"(phagophore assembly site)|go:"GO:0000422"(autophagy of mitochondrion)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005811"(lipid droplet)|go:"GO:0019898"(extrinsic component of membrane)|go:"GO:0032266"(phosphatidylinositol-3-phosphate binding)|go:"GO:0034045"(phagophore assembly site membrane)|go:"GO:0034727"(piecemeal microautophagy of the nucleus)|go:"GO:0044805"(late nucleophagy)|interpro:IPR015412(ATG2, C-terminal)|interpro:IPR026849|interpro:IPR026854|rcsb pdb:6KLR|go:"GO:0061709"(reticulophagy) refseq:NP_005104.3|refseq:XP_011535722.1|ensembl:ENSG00000066455(gene)|ensembl:ENST00000163416(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0000301"(retrograde transport, vesicle recycling within Golgi)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005801"(cis-Golgi network)|go:"GO:0007030"(Golgi organization)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030133"(transport vesicle)|go:"GO:0031985"(Golgi cisterna)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0048193"(Golgi vesicle transport)|interpro:IPR019177|reactome:R-HSA-6811438|go:"GO:0031267"(small GTPase binding) - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/10/21 2020/11/06 rogid:RC80jQqKw4ekVFudqz/IunWCEMA9606 rogid:PtiO2qhE4u4CFxYqL+bqph4lmT09606 rigid:319IsGV1oRp3OLZk5khzgtmEExU false enhanced green fluorescent protein tag:n-n|sufficient binding region:1776-1820 - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q2TAZ0 uniprotkb:O96008 intact:EBI-2514077|intact:EBI-28978291|uniprotkb:Q8TAI8|uniprotkb:O43154|uniprotkb:Q14DM2|uniprotkb:Q7Z6K8|uniprotkb:Q6ZTV2|uniprotkb:Q96HH7|uniprotkb:Q8IVY5|ensembl:ENSP00000366475 intact:EBI-1057581|uniprotkb:Q86VW4|uniprotkb:Q8WY09|uniprotkb:Q8WY10|uniprotkb:Q8WY11|uniprotkb:Q9BR95|uniprotkb:A0A024R0P9|ensembl:ENSP00000252487|ensembl:ENSP00000385184|ensembl:ENSP00000410339 psi-mi:atg2a_human(display_long)|uniprotkb:ATG2A(gene name)|psi-mi:ATG2A(display_short)|uniprotkb:KIAA0404(gene name synonym) psi-mi:tom40_human(display_long)|uniprotkb:TOMM40(gene name)|psi-mi:TOMM40(display_short)|uniprotkb:PEREC1(gene name synonym)|uniprotkb:TOM40(gene name synonym)|uniprotkb:C19orf1(gene name synonym)|uniprotkb:Translocase of outer membrane 40 kDa subunit homolog(gene name synonym)|uniprotkb:Protein Haymaker(gene name synonym)|uniprotkb:p38.5(gene name synonym) psi-mi:"MI:0030"(cross-linking study) Tang et al. (2019) imex:IM-28478|pubmed:31412244 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-26443127|imex:IM-28478-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:XP_011543165.1|ensembl:ENSP00000366475|ensembl:ENST00000421419|ensembl:ENSP00000410522|refseq:NP_055919.2|ensembl:ENSG00000110046(gene)|ensembl:ENST00000377264(transcript)|go:"GO:0000045"(autophagosome assembly)|go:"GO:0000407"(phagophore assembly site)|go:"GO:0000422"(autophagy of mitochondrion)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005811"(lipid droplet)|go:"GO:0019898"(extrinsic component of membrane)|go:"GO:0032266"(phosphatidylinositol-3-phosphate binding)|go:"GO:0034045"(phagophore assembly site membrane)|go:"GO:0034727"(piecemeal microautophagy of the nucleus)|go:"GO:0044805"(late nucleophagy)|interpro:IPR015412(ATG2, C-terminal)|interpro:IPR026849|interpro:IPR026854|rcsb pdb:6KLR|go:"GO:0061709"(reticulophagy) refseq:NP_001122388.1|refseq:NP_001122389.1|refseq:NP_006105.1|ensembl:ENSG00000130204(gene)|ensembl:ENST00000252487(transcript)|ensembl:ENST00000405636(transcript)|ensembl:ENST00000426677(transcript)|go:"GO:0005739"(mitochondrion)|go:"GO:0005742"(mitochondrial outer membrane translocase complex)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005829"(cytosol)|go:"GO:0006626"(protein targeting to mitochondrion)|go:"GO:0006811"(ion transport)|go:"GO:0008320"(protein transmembrane transporter activity)|go:"GO:0015288"(porin activity)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030150"(protein import into mitochondrial matrix)|go:"GO:0031307"(integral component of mitochondrial outer membrane)|go:"GO:0044233"(mitochondria-associated endoplasmic reticulum membrane)|go:"GO:0046930"(pore complex)|interpro:IPR023614|interpro:IPR027246|interpro:IPR037930|rcsb pdb:7CK6|rcsb pdb:7CP9|reactome:R-HSA-1268020|reactome:R-HSA-5205685|go:"GO:0005741"(mitochondrial outer membrane) - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/10/21 2020/11/06 rogid:RC80jQqKw4ekVFudqz/IunWCEMA9606 rogid:BBV//Cb2ekmDNGHNrZuAXRgS++Y9606 rigid:319IsGV1oRp3OLZk5khzgtmEExU false enhanced green fluorescent protein tag:n-n|sufficient binding region:1776-1820 - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q2TAZ0 uniprotkb:Q5T9A4 intact:EBI-2514077|intact:EBI-28978291|uniprotkb:Q8TAI8|uniprotkb:O43154|uniprotkb:Q14DM2|uniprotkb:Q7Z6K8|uniprotkb:Q6ZTV2|uniprotkb:Q96HH7|uniprotkb:Q8IVY5|ensembl:ENSP00000366475 intact:EBI-1384144|uniprotkb:Q6ZRB5|uniprotkb:Q9BUK4|uniprotkb:Q9ULE7|uniprotkb:A8K3H1|ensembl:ENSP00000500094 psi-mi:atg2a_human(display_long)|uniprotkb:ATG2A(gene name)|psi-mi:ATG2A(display_short)|uniprotkb:KIAA0404(gene name synonym) psi-mi:atd3b_human(display_long)|uniprotkb:TOB3(gene name synonym)|uniprotkb:AAA-TOB3(gene name synonym)|uniprotkb:KIAA1273(gene name synonym)|uniprotkb:ATAD3B(gene name)|psi-mi:ATAD3B(display_short) psi-mi:"MI:0030"(cross-linking study) Tang et al. (2019) imex:IM-28478|pubmed:31412244 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-26443127|imex:IM-28478-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:XP_011543165.1|ensembl:ENSP00000366475|ensembl:ENST00000421419|ensembl:ENSP00000410522|refseq:NP_055919.2|ensembl:ENSG00000110046(gene)|ensembl:ENST00000377264(transcript)|go:"GO:0000045"(autophagosome assembly)|go:"GO:0000407"(phagophore assembly site)|go:"GO:0000422"(autophagy of mitochondrion)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005811"(lipid droplet)|go:"GO:0019898"(extrinsic component of membrane)|go:"GO:0032266"(phosphatidylinositol-3-phosphate binding)|go:"GO:0034045"(phagophore assembly site membrane)|go:"GO:0034727"(piecemeal microautophagy of the nucleus)|go:"GO:0044805"(late nucleophagy)|interpro:IPR015412(ATG2, C-terminal)|interpro:IPR026849|interpro:IPR026854|rcsb pdb:6KLR|go:"GO:0061709"(reticulophagy) refseq:NP_114127.3|refseq:NP_001304167.1|ensembl:ENSG00000160072(gene)|ensembl:ENST00000673477(transcript)|go:"GO:0005524"(ATP binding)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005886"(plasma membrane)|go:"GO:0007005"(mitochondrion organization)|go:"GO:0008270"(zinc ion binding)|go:"GO:0030667"(secretory granule membrane)|go:"GO:0101003"(ficolin-1-rich granule membrane)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR003959(AAA ATPase, core)|interpro:IPR021911|interpro:IPR027417|interpro:IPR039188|mint:Q5T9A4|reactome:R-HSA-6798695 - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/10/21 2020/11/06 rogid:RC80jQqKw4ekVFudqz/IunWCEMA9606 rogid:2W52iPQhTBU2apShm8xhfenV1mU9606 rigid:319IsGV1oRp3OLZk5khzgtmEExU false enhanced green fluorescent protein tag:n-n|sufficient binding region:1776-1820 - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q2TAZ0 uniprotkb:Q5VV42 intact:EBI-2514077|intact:EBI-28978291|uniprotkb:Q8TAI8|uniprotkb:O43154|uniprotkb:Q14DM2|uniprotkb:Q7Z6K8|uniprotkb:Q6ZTV2|uniprotkb:Q96HH7|uniprotkb:Q8IVY5|ensembl:ENSP00000366475 intact:EBI-10194801|uniprotkb:Q6P385|uniprotkb:Q6ZR27|uniprotkb:A8K6S0|uniprotkb:Q9NXB3|ensembl:ENSP00000274695|ensembl:ENSP00000367873 psi-mi:atg2a_human(display_long)|uniprotkb:ATG2A(gene name)|psi-mi:ATG2A(display_short)|uniprotkb:KIAA0404(gene name synonym) psi-mi:cdkal_human(display_long)|uniprotkb:CDKAL1(gene name)|psi-mi:CDKAL1(display_short)|uniprotkb:CDK5 regulatory subunit-associated protein 1-like 1(gene name synonym)|uniprotkb:"tRNA-t(6)A37 methylthiotransferase"(gene name synonym) psi-mi:"MI:0030"(cross-linking study) Tang et al. (2019) imex:IM-28478|pubmed:31412244 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-26443127|imex:IM-28478-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:XP_011543165.1|ensembl:ENSP00000366475|ensembl:ENST00000421419|ensembl:ENSP00000410522|refseq:NP_055919.2|ensembl:ENSG00000110046(gene)|ensembl:ENST00000377264(transcript)|go:"GO:0000045"(autophagosome assembly)|go:"GO:0000407"(phagophore assembly site)|go:"GO:0000422"(autophagy of mitochondrion)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005811"(lipid droplet)|go:"GO:0019898"(extrinsic component of membrane)|go:"GO:0032266"(phosphatidylinositol-3-phosphate binding)|go:"GO:0034045"(phagophore assembly site membrane)|go:"GO:0034727"(piecemeal microautophagy of the nucleus)|go:"GO:0044805"(late nucleophagy)|interpro:IPR015412(ATG2, C-terminal)|interpro:IPR026849|interpro:IPR026854|rcsb pdb:6KLR|go:"GO:0061709"(reticulophagy) refseq:NP_060244.2|ensembl:ENSG00000145996(gene)|ensembl:ENST00000274695(transcript)|ensembl:ENST00000378610(transcript)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005791"(rough endoplasmic reticulum)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0035598"(N6-threonylcarbomyladenosine methylthiotransferase activity)|go:"GO:0035600"(tRNA methylthiolation)|go:"GO:0046872"(metal ion binding)|go:"GO:0051539"(4 iron, 4 sulfur cluster binding)|go:"GO:0061712"("tRNA (N(6)-L-threonylcarbamoyladenosine(37)-C(2))-methylthiotransferase")|go:"GO:1990145"(maintenance of translational fidelity)|interpro:IPR002792(Deoxyribonuclease/rho motif-related TRAM)|interpro:IPR005839(Protein of unknown function UPF0004)|interpro:IPR006466(MiaB-like tRNA modifying enzyme, archaeal-type)|interpro:IPR006638(Elongator protein 3/MiaB/NifB)|interpro:IPR007197(Radical SAM)|interpro:IPR013848(Protein of unknown function UPF0004, N-terminal)|interpro:IPR020612|interpro:IPR023404|interpro:IPR038135|mint:Q5VV42|reactome:R-HSA-6782315 - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/10/21 2020/11/06 rogid:RC80jQqKw4ekVFudqz/IunWCEMA9606 rogid:wBMBRPqWqalOHuLyrwr+2KvlHoQ9606 rigid:319IsGV1oRp3OLZk5khzgtmEExU false enhanced green fluorescent protein tag:n-n|sufficient binding region:1776-1820 - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q2TAZ0 uniprotkb:Q07820 intact:EBI-2514077|intact:EBI-28978291|uniprotkb:Q8TAI8|uniprotkb:O43154|uniprotkb:Q14DM2|uniprotkb:Q7Z6K8|uniprotkb:Q6ZTV2|uniprotkb:Q96HH7|uniprotkb:Q8IVY5|ensembl:ENSP00000366475 intact:EBI-1003422|uniprotkb:Q9HD91|uniprotkb:Q9NRQ3|uniprotkb:Q9NRQ4|uniprotkb:Q9UHR7|uniprotkb:Q9UHR8|uniprotkb:Q9UHR9|uniprotkb:Q9UNJ1|uniprotkb:B2R6B2|uniprotkb:D3DV03|uniprotkb:D3DV04|ensembl:ENSP00000358022|ensembl:ENSP00000502859 psi-mi:atg2a_human(display_long)|uniprotkb:ATG2A(gene name)|psi-mi:ATG2A(display_short)|uniprotkb:KIAA0404(gene name synonym) psi-mi:mcl1_human(display_long)|uniprotkb:Bcl-2-related protein EAT/mcl1(gene name synonym)|uniprotkb:mcl1/EAT(gene name synonym)|uniprotkb:MCL1(gene name)|psi-mi:MCL1(display_short)|uniprotkb:BCL2L3(gene name synonym)|uniprotkb:Bcl-2-like protein 3(gene name synonym) psi-mi:"MI:0030"(cross-linking study) Tang et al. (2019) imex:IM-28478|pubmed:31412244 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-26443127|imex:IM-28478-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:XP_011543165.1|ensembl:ENSP00000366475|ensembl:ENST00000421419|ensembl:ENSP00000410522|refseq:NP_055919.2|ensembl:ENSG00000110046(gene)|ensembl:ENST00000377264(transcript)|go:"GO:0000045"(autophagosome assembly)|go:"GO:0000407"(phagophore assembly site)|go:"GO:0000422"(autophagy of mitochondrion)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005811"(lipid droplet)|go:"GO:0019898"(extrinsic component of membrane)|go:"GO:0032266"(phosphatidylinositol-3-phosphate binding)|go:"GO:0034045"(phagophore assembly site membrane)|go:"GO:0034727"(piecemeal microautophagy of the nucleus)|go:"GO:0044805"(late nucleophagy)|interpro:IPR015412(ATG2, C-terminal)|interpro:IPR026849|interpro:IPR026854|rcsb pdb:6KLR|go:"GO:0061709"(reticulophagy) refseq:NP_001184249.1|refseq:NP_068779.1|refseq:NP_877495.1|go:"GO:0016021"(integral component of membrane)|go:"GO:0019725"(cellular homeostasis)|go:"GO:0034097"(response to cytokine)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0051434"(BH3 domain binding)|go:"GO:0097136"(Bcl-2 family protein complex)|go:"GO:0097192"(extrinsic apoptotic signaling pathway in absence of ligand)|go:"GO:1903378"(positive regulation of oxidative stress-induced neuron intrinsic apoptotic signaling pathway)|go:"GO:2000811"(negative regulation of anoikis)|ensembl:ENSG00000143384(gene)|go:"GO:2001020"(regulation of response to DNA damage stimulus)|ensembl:ENST00000369026(transcript)|ensembl:ENST00000678770(transcript)|go:"GO:2001240"(negative regulation of extrinsic apoptotic signaling pathway in absence of ligand)|go:"GO:0001709"(cell fate determination)|go:"GO:2001243"(negative regulation of intrinsic apoptotic signaling pathway)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|interpro:IPR002475(BCL2-like apoptosis inhibitor)|go:"GO:0005741"(mitochondrial outer membrane)|interpro:IPR013281(Apoptosis regulator, Mcl-1)|go:"GO:0005829"(cytosol)|go:"GO:0008320"(protein transmembrane transporter activity)|go:"GO:0008630"(intrinsic apoptotic signaling pathway in response to DNA damage)|go:"GO:0010507"(negative regulation of autophagy)|go:"GO:0016020"(membrane)|interpro:IPR020717|interpro:IPR020726|interpro:IPR020728|rcsb pdb:6QFI|rcsb pdb:6QFM|rcsb pdb:6QFQ|interpro:IPR026298|interpro:IPR036834|rcsb pdb:6QGD|mint:Q07820|rcsb pdb:2KBW|rcsb pdb:2MHS|rcsb pdb:2NL9|rcsb pdb:2NLA|rcsb pdb:6QXJ|rcsb pdb:2PQK|rcsb pdb:6QYK|rcsb pdb:3D7V|rcsb pdb:6QYL|rcsb pdb:3IO9|rcsb pdb:6QYN|rcsb pdb:3KJ0|rcsb pdb:6QYO|rcsb pdb:3KJ1|rcsb pdb:3KJ2|rcsb pdb:6QYP|rcsb pdb:3KZ0|rcsb pdb:6QZ5|rcsb pdb:3MK8|rcsb pdb:3PK1|rcsb pdb:3TWU|rcsb pdb:3WIX|rcsb pdb:3WIY|rcsb pdb:6QZ6|rcsb pdb:4BPI|rcsb pdb:4BPJ|rcsb pdb:4HW2|rcsb pdb:4HW3|rcsb pdb:4HW4|rcsb pdb:4OQ5|rcsb pdb:4OQ6|rcsb pdb:4WGI|rcsb pdb:6QZ7|rcsb pdb:4WMR|rcsb pdb:4WMS|rcsb pdb:4WMT|rcsb pdb:4WMU|rcsb pdb:4WMV|rcsb pdb:4WMW|rcsb pdb:4WMX|rcsb pdb:4ZBF|rcsb pdb:4ZBI|rcsb pdb:5C3F|rcsb pdb:5C6H|rcsb pdb:5FC4|rcsb pdb:5FDO|rcsb pdb:5FDR|rcsb pdb:5IEZ|rcsb pdb:5IF4|rcsb pdb:6QZ8|rcsb pdb:5JSB|rcsb pdb:5KU9|rcsb pdb:5LOF|rcsb pdb:5MES|rcsb pdb:5MEV|rcsb pdb:5UUM|rcsb pdb:5VKC|rcsb pdb:5VX2|rcsb pdb:5W89|rcsb pdb:6QZB|rcsb pdb:5W8F|rcsb pdb:6B4L|rcsb pdb:6B4U|rcsb pdb:6STJ|rcsb pdb:6BW2|rcsb pdb:6BW8|rcsb pdb:6FS0|rcsb pdb:6FS1|rcsb pdb:6FS2|rcsb pdb:6MBD|rcsb pdb:6MBE|rcsb pdb:6NE5|rcsb pdb:6O4U|rcsb pdb:6O6F|rcsb pdb:6O6G|rcsb pdb:6OQB|rcsb pdb:6U63|rcsb pdb:6OQC|rcsb pdb:6U64|rcsb pdb:6U65|rcsb pdb:6OQD|rcsb pdb:6OQN|rcsb pdb:6OVC|rcsb pdb:6P3P|rcsb pdb:6QB3|rcsb pdb:6QB4|rcsb pdb:6QB6|rcsb pdb:6QFC|rcsb pdb:6U67|rcsb pdb:6U6F|rcsb pdb:6UA3|rcsb pdb:6UAB|rcsb pdb:6UD2|rcsb pdb:6UDI|rcsb pdb:6UDU|rcsb pdb:6UDV|rcsb pdb:6UDX|rcsb pdb:6UDY|rcsb pdb:6VBX|rcsb pdb:6YBG|rcsb pdb:6YBJ|rcsb pdb:6YBK|rcsb pdb:6YBL|rcsb pdb:6UDT|rcsb pdb:6ZIE|reactome:R-HSA-6785807|dip:DIP-231N - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/10/21 2020/11/06 rogid:RC80jQqKw4ekVFudqz/IunWCEMA9606 rogid:zHymH4IKoOVjBLtkMF1dmNmH2DU9606 rigid:319IsGV1oRp3OLZk5khzgtmEExU false enhanced green fluorescent protein tag:n-n|sufficient binding region:1776-1820 - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q2TAZ0 uniprotkb:Q8TEM1 intact:EBI-2514077|intact:EBI-28978291|uniprotkb:Q8TAI8|uniprotkb:O43154|uniprotkb:Q14DM2|uniprotkb:Q7Z6K8|uniprotkb:Q6ZTV2|uniprotkb:Q96HH7|uniprotkb:Q8IVY5|ensembl:ENSP00000366475 intact:EBI-372826|uniprotkb:A6NN56|uniprotkb:O94980|uniprotkb:Q6NXG6|uniprotkb:Q8NBJ1|uniprotkb:Q9H6C8|uniprotkb:Q9UFP3|ensembl:ENSP00000254508 psi-mi:atg2a_human(display_long)|uniprotkb:ATG2A(gene name)|psi-mi:ATG2A(display_short)|uniprotkb:KIAA0404(gene name synonym) psi-mi:po210_human(display_long)|uniprotkb:KIAA0906(gene name synonym)|uniprotkb:NUP210(gene name)|psi-mi:NUP210(display_short)|uniprotkb:PSEC0245(orf name)|uniprotkb:Nuclear envelope pore membrane protein POM 210(gene name synonym)|uniprotkb:Pore membrane protein of 210 kDa(gene name synonym)|uniprotkb:Nucleoporin Nup210(gene name synonym) psi-mi:"MI:0030"(cross-linking study) Tang et al. (2019) imex:IM-28478|pubmed:31412244 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-26443127|imex:IM-28478-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:XP_011543165.1|ensembl:ENSP00000366475|ensembl:ENST00000421419|ensembl:ENSP00000410522|refseq:NP_055919.2|ensembl:ENSG00000110046(gene)|ensembl:ENST00000377264(transcript)|go:"GO:0000045"(autophagosome assembly)|go:"GO:0000407"(phagophore assembly site)|go:"GO:0000422"(autophagy of mitochondrion)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005811"(lipid droplet)|go:"GO:0019898"(extrinsic component of membrane)|go:"GO:0032266"(phosphatidylinositol-3-phosphate binding)|go:"GO:0034045"(phagophore assembly site membrane)|go:"GO:0034727"(piecemeal microautophagy of the nucleus)|go:"GO:0044805"(late nucleophagy)|interpro:IPR015412(ATG2, C-terminal)|interpro:IPR026849|interpro:IPR026854|rcsb pdb:6KLR|go:"GO:0061709"(reticulophagy) reactome:R-HSA-9610379|refseq:NP_079199.2|ensembl:ENSG00000132182(gene)|ensembl:ENST00000254508(transcript)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005643"(nuclear pore)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0015031"(protein transport)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0031965"(nuclear membrane)|go:"GO:0051028"(mRNA transport)|go:"GO:0065003"(protein-containing complex assembly)|interpro:IPR003343(Bacterial Ig-like, group 2)|interpro:IPR008964(Invasin/intimin cell-adhesion)|mint:Q8TEM1|reactome:R-HSA-1169408|reactome:R-HSA-159227|reactome:R-HSA-159230|reactome:R-HSA-159231|reactome:R-HSA-159236|reactome:R-HSA-165054|reactome:R-HSA-168271|reactome:R-HSA-168276|reactome:R-HSA-168325|reactome:R-HSA-168333|reactome:R-HSA-170822|reactome:R-HSA-180746|reactome:R-HSA-180910|reactome:R-HSA-191859|reactome:R-HSA-3108214|reactome:R-HSA-3232142|reactome:R-HSA-3301854|reactome:R-HSA-3371453|reactome:R-HSA-4085377|reactome:R-HSA-4551638|reactome:R-HSA-4570464|reactome:R-HSA-4615885|reactome:R-HSA-5578749|reactome:R-HSA-5619107|reactome:R-HSA-6784531|reactome:R-HSA-9609690 - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/10/21 2020/11/06 rogid:RC80jQqKw4ekVFudqz/IunWCEMA9606 rogid:udIemFThWYk0VC21Ml4EDDQWXlg9606 rigid:319IsGV1oRp3OLZk5khzgtmEExU false enhanced green fluorescent protein tag:n-n|sufficient binding region:1776-1820 - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q2TAZ0 uniprotkb:Q9C0E8 intact:EBI-2514077|intact:EBI-28978291|uniprotkb:Q8TAI8|uniprotkb:O43154|uniprotkb:Q14DM2|uniprotkb:Q7Z6K8|uniprotkb:Q6ZTV2|uniprotkb:Q96HH7|uniprotkb:Q8IVY5|ensembl:ENSP00000366475 intact:EBI-1047206|ensembl:ENSP00000272748|uniprotkb:Q2M2V8|uniprotkb:Q2YD99|uniprotkb:Q658W8|uniprotkb:Q8N5V9|uniprotkb:Q96MS5|uniprotkb:B7ZLA8 psi-mi:atg2a_human(display_long)|uniprotkb:ATG2A(gene name)|psi-mi:ATG2A(display_short)|uniprotkb:KIAA0404(gene name synonym) psi-mi:lnp_human(display_long)|uniprotkb:ER junction formation factor lunapark(gene name synonym)|uniprotkb:LNPK(gene name)|psi-mi:LNPK(display_short)|uniprotkb:KIAA1715(gene name synonym)|uniprotkb:LNP(gene name synonym) psi-mi:"MI:0030"(cross-linking study) Tang et al. (2019) imex:IM-28478|pubmed:31412244 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-26443127|imex:IM-28478-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:XP_011543165.1|ensembl:ENSP00000366475|ensembl:ENST00000421419|ensembl:ENSP00000410522|refseq:NP_055919.2|ensembl:ENSG00000110046(gene)|ensembl:ENST00000377264(transcript)|go:"GO:0000045"(autophagosome assembly)|go:"GO:0000407"(phagophore assembly site)|go:"GO:0000422"(autophagy of mitochondrion)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005811"(lipid droplet)|go:"GO:0019898"(extrinsic component of membrane)|go:"GO:0032266"(phosphatidylinositol-3-phosphate binding)|go:"GO:0034045"(phagophore assembly site membrane)|go:"GO:0034727"(piecemeal microautophagy of the nucleus)|go:"GO:0044805"(late nucleophagy)|interpro:IPR015412(ATG2, C-terminal)|interpro:IPR026849|interpro:IPR026854|rcsb pdb:6KLR|go:"GO:0061709"(reticulophagy) ensembl:ENSG00000144320(gene)|ensembl:ENST00000272748(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0007029"(endoplasmic reticulum organization)|go:"GO:0007596"(blood coagulation)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030176"(integral component of endoplasmic reticulum membrane)|go:"GO:0032330"(regulation of chondrocyte differentiation)|go:"GO:0035115"(embryonic forelimb morphogenesis)|go:"GO:0042733"(embryonic digit morphogenesis)|refseq:NP_085153.1|refseq:NP_001291937.1|refseq:NP_001291938.1|refseq:NP_001291940.1|go:"GO:0042802"(identical protein binding)|go:"GO:0046872"(metal ion binding)|go:"GO:0060173"(limb development)|go:"GO:0071782"(endoplasmic reticulum tubular network)|go:"GO:0071786"(endoplasmic reticulum tubular network organization)|go:"GO:0071788"(endoplasmic reticulum tubular network maintenance)|go:"GO:0098826"(endoplasmic reticulum tubular network membrane)|go:"GO:1903373"(positive regulation of endoplasmic reticulum tubular network organization)|interpro:IPR019273|interpro:IPR040115|refseq:XP_006712846.1|refseq:XP_016860544.1 - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/10/21 2020/11/06 rogid:RC80jQqKw4ekVFudqz/IunWCEMA9606 rogid:7iBa9RbcYnDjAjIU4v0rez5Bhn49606 rigid:319IsGV1oRp3OLZk5khzgtmEExU false enhanced green fluorescent protein tag:n-n|sufficient binding region:1776-1820 - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q2TAZ0 uniprotkb:Q9Y2W6 intact:EBI-2514077|intact:EBI-28978291|uniprotkb:Q8TAI8|uniprotkb:O43154|uniprotkb:Q14DM2|uniprotkb:Q7Z6K8|uniprotkb:Q6ZTV2|uniprotkb:Q96HH7|uniprotkb:Q8IVY5|ensembl:ENSP00000366475 intact:EBI-12842466|ensembl:ENSP00000357812|ensembl:ENSP00000357815|ensembl:ENSP00000357819|ensembl:ENSP00000395718|uniprotkb:D3DV24|uniprotkb:Q5SZR3|uniprotkb:Q5SZR5|uniprotkb:Q8N582|uniprotkb:Q9NYV5 psi-mi:atg2a_human(display_long)|uniprotkb:ATG2A(gene name)|psi-mi:ATG2A(display_short)|uniprotkb:KIAA0404(gene name synonym) psi-mi:tdrkh_human(display_long)|uniprotkb:TDRKH(gene name)|psi-mi:TDRKH(display_short)|uniprotkb:TDRD2(gene name synonym)|uniprotkb:Tudor domain-containing protein 2(gene name synonym) psi-mi:"MI:0030"(cross-linking study) Tang et al. (2019) imex:IM-28478|pubmed:31412244 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-26443127|imex:IM-28478-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:XP_011543165.1|ensembl:ENSP00000366475|ensembl:ENST00000421419|ensembl:ENSP00000410522|refseq:NP_055919.2|ensembl:ENSG00000110046(gene)|ensembl:ENST00000377264(transcript)|go:"GO:0000045"(autophagosome assembly)|go:"GO:0000407"(phagophore assembly site)|go:"GO:0000422"(autophagy of mitochondrion)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005811"(lipid droplet)|go:"GO:0019898"(extrinsic component of membrane)|go:"GO:0032266"(phosphatidylinositol-3-phosphate binding)|go:"GO:0034045"(phagophore assembly site membrane)|go:"GO:0034727"(piecemeal microautophagy of the nucleus)|go:"GO:0044805"(late nucleophagy)|interpro:IPR015412(ATG2, C-terminal)|interpro:IPR026849|interpro:IPR026854|rcsb pdb:6KLR|go:"GO:0061709"(reticulophagy) ensembl:ENSG00000182134(gene)|ensembl:ENST00000368822(transcript)|ensembl:ENST00000368824(transcript)|ensembl:ENST00000368827(transcript)|ensembl:ENST00000458431(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0005739"(mitochondrion)|go:"GO:0007140"(male meiotic nuclear division)|go:"GO:0007283"(spermatogenesis)|go:"GO:0009566"(fertilization)|go:"GO:0030154"(cell differentiation)|go:"GO:0031047"(gene silencing by RNA)|go:"GO:0034587"(piRNA metabolic process)|go:"GO:0043046"(DNA methylation involved in gamete generation)|go:"GO:0071546"(pi-body)|go:"GO:0071547"(piP-body)|interpro:IPR002999(Tudor)|interpro:IPR004087(K Homology)|interpro:IPR004088(K Homology, type 1)|interpro:IPR035437|interpro:IPR036612|mint:Q9Y2W6|rcsb pdb:2DIQ|rcsb pdb:3FDR|rcsb pdb:5J39|rcsb pdb:6B57|rcsb pdb:6PI7|reactome:R-HSA-5601884|refseq:NP_001077432.1|refseq:NP_001077433.1|refseq:NP_001077434.1|refseq:NP_006853.2|refseq:XP_016855611.1|refseq:XP_016855612.1|refseq:XP_016855613.1|refseq:XP_016855614.1|refseq:XP_016855615.1|refseq:XP_016855616.1|dip:DIP-59459N - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/10/21 2020/11/06 rogid:RC80jQqKw4ekVFudqz/IunWCEMA9606 rogid:pP4akpV5Kqvd0p+5V750mkXASPg9606 rigid:319IsGV1oRp3OLZk5khzgtmEExU false enhanced green fluorescent protein tag:n-n|sufficient binding region:1776-1820 - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q2TAZ0 uniprotkb:O95721 intact:EBI-2514077|intact:EBI-28978291|uniprotkb:Q8TAI8|uniprotkb:O43154|uniprotkb:Q14DM2|uniprotkb:Q7Z6K8|uniprotkb:Q6ZTV2|uniprotkb:Q96HH7|uniprotkb:Q8IVY5|ensembl:ENSP00000366475 intact:EBI-490676|ensembl:ENSP00000215730 psi-mi:atg2a_human(display_long)|uniprotkb:ATG2A(gene name)|psi-mi:ATG2A(display_short)|uniprotkb:KIAA0404(gene name synonym) psi-mi:snp29_human(display_long)|uniprotkb:Vesicle-membrane fusion protein SNAP-29(gene name synonym)|uniprotkb:Soluble 29 kDa NSF attachment protein(gene name synonym)|uniprotkb:SNAP29(gene name)|psi-mi:SNAP29(display_short) psi-mi:"MI:0030"(cross-linking study) Tang et al. (2019) imex:IM-28478|pubmed:31412244 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-26443127|imex:IM-28478-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:XP_011543165.1|ensembl:ENSP00000366475|ensembl:ENST00000421419|ensembl:ENSP00000410522|refseq:NP_055919.2|ensembl:ENSG00000110046(gene)|ensembl:ENST00000377264(transcript)|go:"GO:0000045"(autophagosome assembly)|go:"GO:0000407"(phagophore assembly site)|go:"GO:0000422"(autophagy of mitochondrion)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005811"(lipid droplet)|go:"GO:0019898"(extrinsic component of membrane)|go:"GO:0032266"(phosphatidylinositol-3-phosphate binding)|go:"GO:0034045"(phagophore assembly site membrane)|go:"GO:0034727"(piecemeal microautophagy of the nucleus)|go:"GO:0044805"(late nucleophagy)|interpro:IPR015412(ATG2, C-terminal)|interpro:IPR026849|interpro:IPR026854|rcsb pdb:6KLR|go:"GO:0061709"(reticulophagy) refseq:NP_004773.1|ensembl:ENSG00000099940(gene)|ensembl:ENST00000215730(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0000421"(autophagosome membrane)|go:"GO:0005484"(SNAP receptor activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005776"(autophagosome)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006887"(exocytosis)|go:"GO:0006903"(vesicle targeting)|go:"GO:0006906"(vesicle fusion)|go:"GO:0015031"(protein transport)|go:"GO:0016082"(synaptic vesicle priming)|go:"GO:0016240"(autophagosome membrane docking)|go:"GO:0019905"(syntaxin binding)|go:"GO:0020018"(ciliary pocket membrane)|go:"GO:0031201"(SNARE complex)|go:"GO:0031629"(synaptic vesicle fusion to presynaptic active zone membrane)|go:"GO:0035577"(azurophil granule membrane)|go:"GO:0060271"(cilium assembly)|go:"GO:0061025"(membrane fusion)|go:"GO:0097352"(autophagosome maturation)|go:"GO:0098793"(presynapse)|interpro:IPR000727(Target SNARE coiled-coil region)|mint:O95721|rcsb pdb:4WY4|rcsb pdb:7BV6|reactome:R-HSA-6798695|reactome:R-HSA-6811438|dip:DIP-56475N - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/10/21 2020/11/06 rogid:RC80jQqKw4ekVFudqz/IunWCEMA9606 rogid:4HyjERPnEDdBgiGt70N9oyrMN1k9606 rigid:319IsGV1oRp3OLZk5khzgtmEExU false enhanced green fluorescent protein tag:n-n|sufficient binding region:1776-1820 - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q2TAZ0 uniprotkb:Q8NHP6 intact:EBI-2514077|intact:EBI-28978291|uniprotkb:Q8TAI8|uniprotkb:O43154|uniprotkb:Q14DM2|uniprotkb:Q7Z6K8|uniprotkb:Q6ZTV2|uniprotkb:Q96HH7|uniprotkb:Q8IVY5|ensembl:ENSP00000366475 intact:EBI-2812848|uniprotkb:Q8NA83|uniprotkb:Q8N3H2|ensembl:ENSP00000369860 psi-mi:atg2a_human(display_long)|uniprotkb:ATG2A(gene name)|psi-mi:ATG2A(display_short)|uniprotkb:KIAA0404(gene name synonym) psi-mi:mspd2_human(display_long)|uniprotkb:MOSPD2(gene name)|psi-mi:MOSPD2(display_short) psi-mi:"MI:0030"(cross-linking study) Tang et al. (2019) imex:IM-28478|pubmed:31412244 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-26443127|imex:IM-28478-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:XP_011543165.1|ensembl:ENSP00000366475|ensembl:ENST00000421419|ensembl:ENSP00000410522|refseq:NP_055919.2|ensembl:ENSG00000110046(gene)|ensembl:ENST00000377264(transcript)|go:"GO:0000045"(autophagosome assembly)|go:"GO:0000407"(phagophore assembly site)|go:"GO:0000422"(autophagy of mitochondrion)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005811"(lipid droplet)|go:"GO:0019898"(extrinsic component of membrane)|go:"GO:0032266"(phosphatidylinositol-3-phosphate binding)|go:"GO:0034045"(phagophore assembly site membrane)|go:"GO:0034727"(piecemeal microautophagy of the nucleus)|go:"GO:0044805"(late nucleophagy)|interpro:IPR015412(ATG2, C-terminal)|interpro:IPR026849|interpro:IPR026854|rcsb pdb:6KLR|go:"GO:0061709"(reticulophagy) refseq:NP_001170946.1|refseq:NP_689794.1|go:"GO:0090023"(positive regulation of neutrophil chemotaxis)|go:"GO:0090026"(positive regulation of monocyte chemotaxis)|go:"GO:0140284"(endoplasmic reticulum-endosome membrane contact site)|interpro:IPR000535(Major sperm protein)|interpro:IPR001251(Cellular retinaldehyde-binding/triple function, C-terminal)|interpro:IPR008962(PapD-like)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR036273|interpro:IPR036865|mint:Q8NHP6|rcsb pdb:6TQS|rcsb pdb:6TQT|rcsb pdb:6TQU|reactome:R-HSA-6798695|reactome:R-HSA-9013405|ensembl:ENSG00000130150(gene)|ensembl:ENST00000380492(transcript)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006935"(chemotaxis)|go:"GO:0016020"(membrane)|go:"GO:0035579"(specific granule membrane)|go:"GO:0044232"(organelle membrane contact site) - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/10/21 2020/11/06 rogid:RC80jQqKw4ekVFudqz/IunWCEMA9606 rogid:WEdwMYKpu1uQll5NXnMm4P51R4E9606 rigid:319IsGV1oRp3OLZk5khzgtmEExU false enhanced green fluorescent protein tag:n-n|sufficient binding region:1776-1820 - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q2TAZ0 uniprotkb:Q6ZRP7 intact:EBI-2514077|intact:EBI-28978291|uniprotkb:Q8TAI8|uniprotkb:O43154|uniprotkb:Q14DM2|uniprotkb:Q7Z6K8|uniprotkb:Q6ZTV2|uniprotkb:Q96HH7|uniprotkb:Q8IVY5|ensembl:ENSP00000366475 intact:EBI-11127401|uniprotkb:Q7Z7B6|uniprotkb:Q8N3G2|uniprotkb:A6NLB0|uniprotkb:Q86VV7|uniprotkb:Q5TB37|uniprotkb:A2CEE0|ensembl:ENSP00000351536 psi-mi:atg2a_human(display_long)|uniprotkb:ATG2A(gene name)|psi-mi:ATG2A(display_short)|uniprotkb:KIAA0404(gene name synonym) psi-mi:qsox2_human(display_long)|uniprotkb:QSOX2(gene name)|psi-mi:QSOX2(display_short)|uniprotkb:Neuroblastoma-derived sulfhydryl oxidase(gene name synonym)|uniprotkb:QSCN6L1(gene name synonym)|uniprotkb:Quiescin Q6-like protein 1(gene name synonym)|uniprotkb:SOXN(gene name synonym) psi-mi:"MI:0030"(cross-linking study) Tang et al. (2019) imex:IM-28478|pubmed:31412244 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-26443127|imex:IM-28478-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:XP_011543165.1|ensembl:ENSP00000366475|ensembl:ENST00000421419|ensembl:ENSP00000410522|refseq:NP_055919.2|ensembl:ENSG00000110046(gene)|ensembl:ENST00000377264(transcript)|go:"GO:0000045"(autophagosome assembly)|go:"GO:0000407"(phagophore assembly site)|go:"GO:0000422"(autophagy of mitochondrion)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005811"(lipid droplet)|go:"GO:0019898"(extrinsic component of membrane)|go:"GO:0032266"(phosphatidylinositol-3-phosphate binding)|go:"GO:0034045"(phagophore assembly site membrane)|go:"GO:0034727"(piecemeal microautophagy of the nucleus)|go:"GO:0044805"(late nucleophagy)|interpro:IPR015412(ATG2, C-terminal)|interpro:IPR026849|interpro:IPR026854|rcsb pdb:6KLR|go:"GO:0061709"(reticulophagy) refseq:NP_859052.3|ensembl:ENSG00000165661(gene)|ensembl:ENST00000358701(transcript)|go:"GO:0003756"(protein disulfide isomerase activity)|go:"GO:0005615"(extracellular space)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0006457"(protein folding)|go:"GO:0016971"(flavin-linked sulfhydryl oxidase activity)|go:"GO:0030173"(integral component of Golgi membrane)|go:"GO:0031965"(nuclear membrane)|interpro:IPR013766(Thioredoxin domain)|interpro:IPR017905|interpro:IPR036249|interpro:IPR036774|interpro:IPR039798|interpro:IPR040986|interpro:IPR041269|interpro:IPR042568 - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/10/21 2020/11/06 rogid:RC80jQqKw4ekVFudqz/IunWCEMA9606 rogid:P58P7yZCL+dIpUXwETr5Ppt/SQw9606 rigid:319IsGV1oRp3OLZk5khzgtmEExU false enhanced green fluorescent protein tag:n-n|sufficient binding region:1776-1820 - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q2TAZ0 uniprotkb:P23634 intact:EBI-2514077|intact:EBI-28978291|uniprotkb:Q8TAI8|uniprotkb:O43154|uniprotkb:Q14DM2|uniprotkb:Q7Z6K8|uniprotkb:Q6ZTV2|uniprotkb:Q96HH7|uniprotkb:Q8IVY5|ensembl:ENSP00000366475 intact:EBI-1174388|uniprotkb:Q13450|uniprotkb:Q13452|uniprotkb:Q13455|uniprotkb:Q16817|uniprotkb:Q7Z3S1|uniprotkb:B1APW6|uniprotkb:B1APW5 psi-mi:atg2a_human(display_long)|uniprotkb:ATG2A(gene name)|psi-mi:ATG2A(display_short)|uniprotkb:KIAA0404(gene name synonym) psi-mi:at2b4_human(display_long)|uniprotkb:Plasma membrane calcium ATPase isoform 4(gene name synonym)|uniprotkb:Plasma membrane calcium pump isoform 4(gene name synonym)|uniprotkb:Matrix-remodeling-associated protein 1(gene name synonym)|uniprotkb:ATP2B4(gene name)|psi-mi:ATP2B4(display_short)|uniprotkb:ATP2B2(gene name synonym)|uniprotkb:MXRA1(gene name synonym) psi-mi:"MI:0030"(cross-linking study) Tang et al. (2019) imex:IM-28478|pubmed:31412244 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-26443127|imex:IM-28478-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:XP_011543165.1|ensembl:ENSP00000366475|ensembl:ENST00000421419|ensembl:ENSP00000410522|refseq:NP_055919.2|ensembl:ENSG00000110046(gene)|ensembl:ENST00000377264(transcript)|go:"GO:0000045"(autophagosome assembly)|go:"GO:0000407"(phagophore assembly site)|go:"GO:0000422"(autophagy of mitochondrion)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005811"(lipid droplet)|go:"GO:0019898"(extrinsic component of membrane)|go:"GO:0032266"(phosphatidylinositol-3-phosphate binding)|go:"GO:0034045"(phagophore assembly site membrane)|go:"GO:0034727"(piecemeal microautophagy of the nucleus)|go:"GO:0044805"(late nucleophagy)|interpro:IPR015412(ATG2, C-terminal)|interpro:IPR026849|interpro:IPR026854|rcsb pdb:6KLR|go:"GO:0061709"(reticulophagy) refseq:NP_001001396.1|refseq:NP_001675.3|go:"GO:0003407"(neural retina development)|go:"GO:0005388"(P-type calcium transporter activity)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0005901"(caveola)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006874"(cellular calcium ion homeostasis)|go:"GO:0007283"(spermatogenesis)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0010751"(negative regulation of nitric oxide mediated signal transduction)|go:"GO:0014832"(urinary bladder smooth muscle contraction)|go:"GO:0015085"(calcium ion transmembrane transporter activity)|go:"GO:0016020"(membrane)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016525"(negative regulation of angiogenesis)|go:"GO:0017080"(sodium channel regulator activity)|go:"GO:0019829"(ATPase-coupled cation transmembrane transporter activity)|go:"GO:0019901"(protein kinase binding)|go:"GO:0021766"(hippocampus development)|go:"GO:0030018"(Z disc)|go:"GO:0030165"(PDZ domain binding)|go:"GO:0030315"(T-tubule)|go:"GO:0030317"(flagellated sperm motility)|go:"GO:0030346"(protein phosphatase 2B binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033138"(positive regulation of peptidyl-serine phosphorylation)|go:"GO:0034220"(ion transmembrane transport)|go:"GO:0036126"(sperm flagellum)|go:"GO:0036487"(nitric-oxide synthase inhibitor activity)|go:"GO:0043005"(neuron projection)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0043537"(negative regulation of blood vessel endothelial cell migration)|go:"GO:0045019"(negative regulation of nitric oxide biosynthetic process)|go:"GO:0045121"(membrane raft)|go:"GO:0046872"(metal ion binding)|go:"GO:0048306"(calcium-dependent protein binding)|go:"GO:0050998"(nitric-oxide synthase binding)|go:"GO:0051001"(negative regulation of nitric-oxide synthase activity)|go:"GO:0051480"(regulation of cytosolic calcium ion concentration)|go:"GO:0051599"(response to hydrostatic pressure)|go:"GO:0070588"(calcium ion transmembrane transport)|go:"GO:0070885"(negative regulation of calcineurin-NFAT signaling cascade)|go:"GO:0071872"(cellular response to epinephrine stimulus)|go:"GO:0097110"(scaffold protein binding)|go:"GO:0097228"(sperm principal piece)|go:"GO:0097553"(calcium ion transmembrane import into cytosol)|go:"GO:0098703"(calcium ion import across plasma membrane)|go:"GO:0098736"(negative regulation of the force of heart contraction)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099059"(integral component of presynaptic active zone membrane)|go:"GO:0140199"(negative regulation of adenylate cyclase-activating adrenergic receptor signaling pathway involved in heart process)|go:"GO:0150104"(transport across blood-brain barrier)|go:"GO:1900082"(negative regulation of arginine catabolic process)|go:"GO:1901660"(calcium ion export)|go:"GO:1902083"(negative regulation of peptidyl-cysteine S-nitrosylation)|go:"GO:1902305"(regulation of sodium ion transmembrane transport)|go:"GO:1902548"(negative regulation of cellular response to vascular endothelial growth factor stimulus)|go:"GO:1902806"(regulation of cell cycle G1/S phase transition)|go:"GO:1903078"(positive regulation of protein localization to plasma membrane)|go:"GO:1903243"(negative regulation of cardiac muscle hypertrophy in response to stress)|go:"GO:1903249"(negative regulation of citrulline biosynthetic process)|go:"GO:1903779"(regulation of cardiac conduction)|go:"GO:1905145"(cellular response to acetylcholine)|go:"GO:2000481"(positive regulation of cAMP-dependent protein kinase activity)|interpro:IPR001757(ATPase, P-type, K/Mg/Cd/Cu/Zn/Na/Ca/Na/H-transporter)|interpro:IPR004014(ATPase, P-type cation-transporter, N-terminal)|interpro:IPR006068(ATPase, P-type cation-transporter, C-terminal)|interpro:IPR006408(Calcium-translocating P-type ATPase, PMCA-type)|interpro:IPR008250(E1-E2 ATPase-associated region)|interpro:IPR018303|interpro:IPR022141|interpro:IPR023214|interpro:IPR023298|interpro:IPR023299|interpro:IPR036412|interpro:IPR044492|rcsb pdb:1CFF|rcsb pdb:2KNE|reactome:R-HSA-418359|reactome:R-HSA-5578775|reactome:R-HSA-936837|mint:P23634|dip:DIP-6128N - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/10/21 2020/11/06 rogid:RC80jQqKw4ekVFudqz/IunWCEMA9606 rogid:XAjzRea7vq4vsbCVKdZRYIWvfBM9606 rigid:319IsGV1oRp3OLZk5khzgtmEExU false enhanced green fluorescent protein tag:n-n|sufficient binding region:1776-1820 - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q2TAZ0 uniprotkb:Q9BRQ6 intact:EBI-2514077|intact:EBI-28978291|uniprotkb:Q8TAI8|uniprotkb:O43154|uniprotkb:Q14DM2|uniprotkb:Q7Z6K8|uniprotkb:Q6ZTV2|uniprotkb:Q96HH7|uniprotkb:Q8IVY5|ensembl:ENSP00000366475 intact:EBI-2557895|ensembl:ENSP00000290913|uniprotkb:D6R9U0|uniprotkb:D6RIB4|uniprotkb:H8Y0Y7 psi-mi:atg2a_human(display_long)|uniprotkb:ATG2A(gene name)|psi-mi:ATG2A(display_short)|uniprotkb:KIAA0404(gene name synonym) psi-mi:mic25_human(display_long)|uniprotkb:CHCHD6(gene name)|psi-mi:CHCHD6(display_short)|uniprotkb:CHCM1(gene name synonym)|uniprotkb:Coiled-coil-helix cristae morphology protein 1(gene name synonym)|uniprotkb:Coiled-coil-helix-coiled-coil-helix domain-containing protein 6(gene name synonym)|uniprotkb:MIC25(gene name synonym) psi-mi:"MI:0030"(cross-linking study) Tang et al. (2019) imex:IM-28478|pubmed:31412244 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-26443127|imex:IM-28478-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:XP_011543165.1|ensembl:ENSP00000366475|ensembl:ENST00000421419|ensembl:ENSP00000410522|refseq:NP_055919.2|ensembl:ENSG00000110046(gene)|ensembl:ENST00000377264(transcript)|go:"GO:0000045"(autophagosome assembly)|go:"GO:0000407"(phagophore assembly site)|go:"GO:0000422"(autophagy of mitochondrion)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005811"(lipid droplet)|go:"GO:0019898"(extrinsic component of membrane)|go:"GO:0032266"(phosphatidylinositol-3-phosphate binding)|go:"GO:0034045"(phagophore assembly site membrane)|go:"GO:0034727"(piecemeal microautophagy of the nucleus)|go:"GO:0044805"(late nucleophagy)|interpro:IPR015412(ATG2, C-terminal)|interpro:IPR026849|interpro:IPR026854|rcsb pdb:6KLR|go:"GO:0061709"(reticulophagy) refseq:NP_115719.1|refseq:NP_001307539.1|ensembl:ENSG00000159685(gene)|ensembl:ENST00000290913(transcript)|go:"GO:0001401"(SAM complex)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005829"(cytosol)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0007007"(inner mitochondrial membrane organization)|go:"GO:0042407"(cristae formation)|go:"GO:0061617"(MICOS complex)|go:"GO:0140275"(MIB complex)|interpro:IPR042860|mint:Q9BRQ6|reactome:R-HSA-8949613 - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/10/21 2020/11/06 rogid:RC80jQqKw4ekVFudqz/IunWCEMA9606 rogid:6jrzreYX6MJWPfMKh2EKqiEca1s9606 rigid:319IsGV1oRp3OLZk5khzgtmEExU false enhanced green fluorescent protein tag:n-n|sufficient binding region:1776-1820 - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q2TAZ0 uniprotkb:P61421 intact:EBI-2514077|intact:EBI-28978291|uniprotkb:Q8TAI8|uniprotkb:O43154|uniprotkb:Q14DM2|uniprotkb:Q7Z6K8|uniprotkb:Q6ZTV2|uniprotkb:Q96HH7|uniprotkb:Q8IVY5|ensembl:ENSP00000366475 intact:EBI-954063|ensembl:ENSP00000290949|uniprotkb:P12953|uniprotkb:Q02547 psi-mi:atg2a_human(display_long)|uniprotkb:ATG2A(gene name)|psi-mi:ATG2A(display_short)|uniprotkb:KIAA0404(gene name synonym) psi-mi:va0d1_human(display_long)|uniprotkb:Vacuolar proton pump subunit d 1(gene name synonym)|uniprotkb:V-ATPase AC39 subunit(gene name synonym)|uniprotkb:V-ATPase 40 kDa accessory protein(gene name synonym)|uniprotkb:32 kDa accessory protein(gene name synonym)|uniprotkb:ATP6V0D1(gene name)|psi-mi:ATP6V0D1(display_short)|uniprotkb:ATP6D(gene name synonym)|uniprotkb:VPATPD(gene name synonym) psi-mi:"MI:0030"(cross-linking study) Tang et al. (2019) imex:IM-28478|pubmed:31412244 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-26443127|imex:IM-28478-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:XP_011543165.1|ensembl:ENSP00000366475|ensembl:ENST00000421419|ensembl:ENSP00000410522|refseq:NP_055919.2|ensembl:ENSG00000110046(gene)|ensembl:ENST00000377264(transcript)|go:"GO:0000045"(autophagosome assembly)|go:"GO:0000407"(phagophore assembly site)|go:"GO:0000422"(autophagy of mitochondrion)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005811"(lipid droplet)|go:"GO:0019898"(extrinsic component of membrane)|go:"GO:0032266"(phosphatidylinositol-3-phosphate binding)|go:"GO:0034045"(phagophore assembly site membrane)|go:"GO:0034727"(piecemeal microautophagy of the nucleus)|go:"GO:0044805"(late nucleophagy)|interpro:IPR015412(ATG2, C-terminal)|interpro:IPR026849|interpro:IPR026854|rcsb pdb:6KLR|go:"GO:0061709"(reticulophagy) ensembl:ENSG00000159720(gene)|ensembl:ENST00000290949(transcript)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005769"(early endosome)|go:"GO:0006879"(cellular iron ion homeostasis)|go:"GO:0007034"(vacuolar transport)|go:"GO:0007035"(vacuolar acidification)|go:"GO:0007420"(brain development)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0010008"(endosome membrane)|go:"GO:0016020"(membrane)|go:"GO:0016241"(regulation of macroautophagy)|go:"GO:0016471"(vacuolar proton-transporting V-type ATPase complex)|go:"GO:0030670"(phagocytic vesicle membrane)|go:"GO:0033179"(proton-transporting V-type ATPase, V0 domain)|go:"GO:0033181"(plasma membrane proton-transporting V-type ATPase complex)|go:"GO:0036295"(cellular response to increased oxygen levels)|go:"GO:0043679"(axon terminus)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0046961"(proton-transporting ATPase activity, rotational mechanism)|go:"GO:0060271"(cilium assembly)|go:"GO:0070062"(extracellular exosome)|go:"GO:1902600"(proton transmembrane transport)|interpro:IPR002843(ATPase, V0/A0 complex, subunit C/D)|interpro:IPR016727(ATPase, V0 complex, subunit D)|interpro:IPR035067|interpro:IPR036079|interpro:IPR044911|mint:P61421|rcsb pdb:6WLW|rcsb pdb:6WM2|rcsb pdb:6WM3|rcsb pdb:6WM4|reactome:R-HSA-1222556|reactome:R-HSA-381038|reactome:R-HSA-77387|reactome:R-HSA-917977|reactome:R-HSA-9639288|reactome:R-HSA-983712|go:"GO:0016324"(apical plasma membrane)|refseq:NP_004682.2|dip:DIP-47435N - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/10/21 2020/11/06 rogid:RC80jQqKw4ekVFudqz/IunWCEMA9606 rogid:3a/yIxEF9LMwAZUR3npGQrw8xNo9606 rigid:319IsGV1oRp3OLZk5khzgtmEExU false enhanced green fluorescent protein tag:n-n|sufficient binding region:1776-1820 - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q2TAZ0 uniprotkb:Q9NR28 intact:EBI-2514077|intact:EBI-28978291|uniprotkb:Q8TAI8|uniprotkb:O43154|uniprotkb:Q14DM2|uniprotkb:Q7Z6K8|uniprotkb:Q6ZTV2|uniprotkb:Q96HH7|uniprotkb:Q8IVY5|ensembl:ENSP00000366475 intact:EBI-517508|uniprotkb:Q96LV0|uniprotkb:Q9BT11|uniprotkb:Q9HAV6|uniprotkb:B2RDQ0|ensembl:ENSP00000442360|ensembl:ENSP00000499058|uniprotkb:Q6W3F3 psi-mi:atg2a_human(display_long)|uniprotkb:ATG2A(gene name)|psi-mi:ATG2A(display_short)|uniprotkb:KIAA0404(gene name synonym) psi-mi:dbloh_human(display_long)|uniprotkb:Second mitochondria-derived activator of caspase(gene name synonym)|uniprotkb:Direct IAP-binding protein with low pI(gene name synonym)|uniprotkb:DIABLO(gene name)|psi-mi:DIABLO(display_short)|uniprotkb:SMAC(gene name synonym) psi-mi:"MI:0030"(cross-linking study) Tang et al. (2019) imex:IM-28478|pubmed:31412244 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-26443127|imex:IM-28478-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:XP_011543165.1|ensembl:ENSP00000366475|ensembl:ENST00000421419|ensembl:ENSP00000410522|refseq:NP_055919.2|ensembl:ENSG00000110046(gene)|ensembl:ENST00000377264(transcript)|go:"GO:0000045"(autophagosome assembly)|go:"GO:0000407"(phagophore assembly site)|go:"GO:0000422"(autophagy of mitochondrion)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005811"(lipid droplet)|go:"GO:0019898"(extrinsic component of membrane)|go:"GO:0032266"(phosphatidylinositol-3-phosphate binding)|go:"GO:0034045"(phagophore assembly site membrane)|go:"GO:0034727"(piecemeal microautophagy of the nucleus)|go:"GO:0044805"(late nucleophagy)|interpro:IPR015412(ATG2, C-terminal)|interpro:IPR026849|interpro:IPR026854|rcsb pdb:6KLR|go:"GO:0061709"(reticulophagy) refseq:NP_001265231.1|refseq:NP_001265232.1|refseq:NP_001265233.1|refseq:NP_001265271.1|refseq:NP_620308.1|refseq:NP_063940.1|ensembl:ENST00000464942(transcript)|ensembl:ENSG00000184047(gene)|ensembl:ENST00000650715(transcript)|go:"GO:0005739"(mitochondrion)|go:"GO:0005758"(mitochondrial intermembrane space)|go:"GO:0005829"(cytosol)|go:"GO:0006915"(apoptotic process)|go:"GO:0006919"(activation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0008625"(extrinsic apoptotic signaling pathway via death domain receptors)|go:"GO:0008631"(intrinsic apoptotic signaling pathway in response to oxidative stress)|go:"GO:0008635"(activation of cysteine-type endopeptidase activity involved in apoptotic process by cytochrome c)|go:"GO:0009898"(cytoplasmic side of plasma membrane)|go:"GO:0035631"(CD40 receptor complex)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0051402"(neuron apoptotic process)|go:"GO:0097193"(intrinsic apoptotic signaling pathway)|interpro:IPR009062(Second mitochondria-derived activator of caspase/direct IAP-binding protein with low PI-like)|interpro:IPR015142(Second mitochondria-derived activator of caspase/Direct IAP-binding protein with low PI)|rcsb pdb:1FEW|dip:DIP-27627N|rcsb pdb:1G3F|rcsb pdb:1G73|rcsb pdb:1OXQ|rcsb pdb:1TW6|rcsb pdb:1XB0|rcsb pdb:1XB1|rcsb pdb:3D9U|rcsb pdb:3UIH|rcsb pdb:3UIJ|rcsb pdb:4TX5|rcsb pdb:6JX6|reactome:R-HSA-111457|reactome:R-HSA-111463|reactome:R-HSA-111464|reactome:R-HSA-111469|reactome:R-HSA-9627069 - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/10/21 2020/11/06 rogid:RC80jQqKw4ekVFudqz/IunWCEMA9606 rogid:PkdIVYOS6o8pglwOXzsyD/frCqI9606 rigid:319IsGV1oRp3OLZk5khzgtmEExU false enhanced green fluorescent protein tag:n-n|sufficient binding region:1776-1820 - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q2TAZ0 uniprotkb:Q9NX40 intact:EBI-2514077|intact:EBI-28978291|uniprotkb:Q8TAI8|uniprotkb:O43154|uniprotkb:Q14DM2|uniprotkb:Q7Z6K8|uniprotkb:Q6ZTV2|uniprotkb:Q96HH7|uniprotkb:Q8IVY5|ensembl:ENSP00000366475 intact:EBI-2683029|uniprotkb:C9K030|uniprotkb:Q9BZE8|ensembl:ENSP00000264312|ensembl:ENSP00000370882|ensembl:ENSP00000423002|ensembl:ENSP00000423909|uniprotkb:G8JLN7 psi-mi:atg2a_human(display_long)|uniprotkb:ATG2A(gene name)|psi-mi:ATG2A(display_short)|uniprotkb:KIAA0404(gene name synonym) psi-mi:ocad1_human(display_long)|uniprotkb:OCIA(gene name synonym)|uniprotkb:Ovarian carcinoma immunoreactive antigen(gene name synonym)|uniprotkb:OCIAD1(gene name)|psi-mi:OCIAD1(display_short)|uniprotkb:ASRIJ(gene name synonym)|uniprotkb:Ovarian cancer immunoreactive antigen domain containing 1(gene name synonym) psi-mi:"MI:0030"(cross-linking study) Tang et al. (2019) imex:IM-28478|pubmed:31412244 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-26443127|imex:IM-28478-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:XP_011543165.1|ensembl:ENSP00000366475|ensembl:ENST00000421419|ensembl:ENSP00000410522|refseq:NP_055919.2|ensembl:ENSG00000110046(gene)|ensembl:ENST00000377264(transcript)|go:"GO:0000045"(autophagosome assembly)|go:"GO:0000407"(phagophore assembly site)|go:"GO:0000422"(autophagy of mitochondrion)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005811"(lipid droplet)|go:"GO:0019898"(extrinsic component of membrane)|go:"GO:0032266"(phosphatidylinositol-3-phosphate binding)|go:"GO:0034045"(phagophore assembly site membrane)|go:"GO:0034727"(piecemeal microautophagy of the nucleus)|go:"GO:0044805"(late nucleophagy)|interpro:IPR015412(ATG2, C-terminal)|interpro:IPR026849|interpro:IPR026854|rcsb pdb:6KLR|go:"GO:0061709"(reticulophagy) refseq:NP_001073309.1|refseq:NP_001073311.2|refseq:NP_001073308.1|refseq:NP_001073310.1|refseq:NP_060300.1|ensembl:ENSG00000109180(gene)|ensembl:ENST00000264312(transcript)|ensembl:ENST00000381473(transcript)|ensembl:ENST00000508293(transcript)|ensembl:ENST00000513391(transcript)|go:"GO:0005764"(lysosome)|go:"GO:0005768"(endosome)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0006897"(endocytosis)|go:"GO:0016020"(membrane)|go:"GO:0046427"(positive regulation of receptor signaling pathway via JAK-STAT)|go:"GO:0061484"(hematopoietic stem cell homeostasis)|go:"GO:2000736"(regulation of stem cell differentiation)|interpro:IPR009764(Ovarian carcinoma immunoreactive antigen)|interpro:IPR040187|mint:Q9NX40|refseq:XP_016863818.1 - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/10/21 2020/11/06 rogid:RC80jQqKw4ekVFudqz/IunWCEMA9606 rogid:e3Ojv8LBlgj056bssUZjEC+MB+Q9606 rigid:319IsGV1oRp3OLZk5khzgtmEExU false enhanced green fluorescent protein tag:n-n|sufficient binding region:1776-1820 - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q2TAZ0 uniprotkb:Q9BZF1 intact:EBI-2514077|intact:EBI-28978291|uniprotkb:Q8TAI8|uniprotkb:O43154|uniprotkb:Q14DM2|uniprotkb:Q7Z6K8|uniprotkb:Q6ZTV2|uniprotkb:Q96HH7|uniprotkb:Q8IVY5|ensembl:ENSP00000366475 intact:EBI-2684038|uniprotkb:Q52LQ3|uniprotkb:Q9P277|uniprotkb:Q8WXP8|uniprotkb:A8K1T2|uniprotkb:E9PE66|uniprotkb:E9PE68|uniprotkb:Q68D75|ensembl:ENSP00000261183 psi-mi:atg2a_human(display_long)|uniprotkb:ATG2A(gene name)|psi-mi:ATG2A(display_short)|uniprotkb:KIAA0404(gene name synonym) psi-mi:osbl8_human(display_long)|uniprotkb:KIAA1451(gene name synonym)|uniprotkb:ORP8(gene name synonym)|uniprotkb:OSBP10(gene name synonym)|uniprotkb:OSBPL8(gene name)|psi-mi:OSBPL8(display_short) psi-mi:"MI:0030"(cross-linking study) Tang et al. (2019) imex:IM-28478|pubmed:31412244 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-26443127|imex:IM-28478-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:XP_011543165.1|ensembl:ENSP00000366475|ensembl:ENST00000421419|ensembl:ENSP00000410522|refseq:NP_055919.2|ensembl:ENSG00000110046(gene)|ensembl:ENST00000377264(transcript)|go:"GO:0000045"(autophagosome assembly)|go:"GO:0000407"(phagophore assembly site)|go:"GO:0000422"(autophagy of mitochondrion)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005811"(lipid droplet)|go:"GO:0019898"(extrinsic component of membrane)|go:"GO:0032266"(phosphatidylinositol-3-phosphate binding)|go:"GO:0034045"(phagophore assembly site membrane)|go:"GO:0034727"(piecemeal microautophagy of the nucleus)|go:"GO:0044805"(late nucleophagy)|interpro:IPR015412(ATG2, C-terminal)|interpro:IPR026849|interpro:IPR026854|rcsb pdb:6KLR|go:"GO:0061709"(reticulophagy) refseq:NP_001003712.1|refseq:NP_065892.1|refseq:NP_001306581.1|refseq:NP_001306584.1|ensembl:ENSG00000091039(gene)|ensembl:ENST00000261183(transcript)|go:"GO:0001786"(phosphatidylserine binding)|go:"GO:0005548"(phospholipid transporter activity)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005829"(cytosol)|go:"GO:0010891"(negative regulation of sequestering of triglyceride)|go:"GO:0015248"(sterol transporter activity)|go:"GO:0015485"(cholesterol binding)|go:"GO:0015914"(phospholipid transport)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030336"(negative regulation of cell migration)|go:"GO:0031965"(nuclear membrane)|go:"GO:0032148"(activation of protein kinase B activity)|go:"GO:0032541"(cortical endoplasmic reticulum)|go:"GO:0032934"(sterol binding)|go:"GO:0036150"(phosphatidylserine acyl-chain remodeling)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0045444"(fat cell differentiation)|go:"GO:0046326"(positive regulation of glucose import)|go:"GO:0046628"(positive regulation of insulin receptor signaling pathway)|go:"GO:0051897"(positive regulation of protein kinase B signaling)|go:"GO:0070273"(phosphatidylinositol-4-phosphate binding)|go:"GO:0090204"(protein localization to nuclear pore)|go:"GO:0140343"(phosphatidylserine transfer activity)|interpro:IPR000648(Oxysterol-binding protein)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR018494|interpro:IPR037239|mint:Q9BZF1|rcsb pdb:1V88|rcsb pdb:5U77|rcsb pdb:5U78|reactome:R-HSA-1482801|refseq:XP_005268678.1|refseq:XP_006719287.1|dip:DIP-56130N - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/10/21 2020/11/06 rogid:RC80jQqKw4ekVFudqz/IunWCEMA9606 rogid:KwZ5DFeGTIM3p/yP3XBNgr/v3O09606 rigid:319IsGV1oRp3OLZk5khzgtmEExU false enhanced green fluorescent protein tag:n-n|sufficient binding region:1776-1820 - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q2TAZ0 uniprotkb:Q8NE86 intact:EBI-2514077|intact:EBI-28978291|uniprotkb:Q8TAI8|uniprotkb:O43154|uniprotkb:Q14DM2|uniprotkb:Q7Z6K8|uniprotkb:Q6ZTV2|uniprotkb:Q96HH7|uniprotkb:Q8IVY5|ensembl:ENSP00000366475 intact:EBI-6552124|ensembl:ENSP00000362144|uniprotkb:B2RDF3|uniprotkb:B3KXV7|uniprotkb:Q96FL3 psi-mi:atg2a_human(display_long)|uniprotkb:ATG2A(gene name)|psi-mi:ATG2A(display_short)|uniprotkb:KIAA0404(gene name synonym) psi-mi:mcu_human(display_long)|uniprotkb:MCU(gene name)|psi-mi:MCU(display_short)|uniprotkb:C10orf42(gene name synonym)|uniprotkb:CCDC109A(gene name synonym)|uniprotkb:Coiled-coil domain-containing protein 109A(gene name synonym) psi-mi:"MI:0030"(cross-linking study) Tang et al. (2019) imex:IM-28478|pubmed:31412244 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-26443127|imex:IM-28478-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:XP_011543165.1|ensembl:ENSP00000366475|ensembl:ENST00000421419|ensembl:ENSP00000410522|refseq:NP_055919.2|ensembl:ENSG00000110046(gene)|ensembl:ENST00000377264(transcript)|go:"GO:0000045"(autophagosome assembly)|go:"GO:0000407"(phagophore assembly site)|go:"GO:0000422"(autophagy of mitochondrion)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005811"(lipid droplet)|go:"GO:0019898"(extrinsic component of membrane)|go:"GO:0032266"(phosphatidylinositol-3-phosphate binding)|go:"GO:0034045"(phagophore assembly site membrane)|go:"GO:0034727"(piecemeal microautophagy of the nucleus)|go:"GO:0044805"(late nucleophagy)|interpro:IPR015412(ATG2, C-terminal)|interpro:IPR026849|interpro:IPR026854|rcsb pdb:6KLR|go:"GO:0061709"(reticulophagy) go:"GO:0031305"(integral component of mitochondrial inner membrane)|go:"GO:0032024"(positive regulation of insulin secretion)|go:"GO:0034704"(calcium channel complex)|go:"GO:0036444"(calcium import into the mitochondrion)|go:"GO:0042593"(glucose homeostasis)|go:"GO:0042802"(identical protein binding)|go:"GO:0051259"(protein complex oligomerization)|go:"GO:0051560"(mitochondrial calcium ion homeostasis)|go:"GO:0051561"(positive regulation of mitochondrial calcium ion concentration)|go:"GO:0090023"(positive regulation of neutrophil chemotaxis)|go:"GO:0090141"(positive regulation of mitochondrial fission)|go:"GO:0090527"(actin filament reorganization)|go:"GO:1990246"(uniplex complex)|interpro:IPR006769(Protein of unknown function DUF607)|interpro:IPR039055|rcsb pdb:4XSJ|rcsb pdb:4XTB|rcsb pdb:5BZ6|rcsb pdb:5KUE|rcsb pdb:5KUG|rcsb pdb:5KUI|rcsb pdb:5KUJ|rcsb pdb:6JG0|rcsb pdb:6K7X|rcsb pdb:6K7Y|rcsb pdb:6KVX|rcsb pdb:6O58|rcsb pdb:6O5B|rcsb pdb:6WDN|rcsb pdb:6WDO|rcsb pdb:6XJV|rcsb pdb:6XJX|reactome:R-HSA-8949215|reactome:R-HSA-8949664|go:"GO:0019722"(calcium-mediated signaling)|ensembl:ENSG00000156026(gene)|ensembl:ENST00000373053(transcript)|go:"GO:0005262"(calcium channel activity)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0006851"(mitochondrial calcium ion transmembrane transport)|go:"GO:0015292"(uniporter activity)|refseq:NP_001257608.1|refseq:NP_001257609.1|refseq:NP_612366.1|dip:DIP-60468N - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/10/21 2020/11/06 rogid:RC80jQqKw4ekVFudqz/IunWCEMA9606 rogid:t2fSATmrk7IEC0nMpquAoPB3CHs9606 rigid:319IsGV1oRp3OLZk5khzgtmEExU false enhanced green fluorescent protein tag:n-n|sufficient binding region:1776-1820 - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q2TAZ0 uniprotkb:Q6P1M0 intact:EBI-2514077|intact:EBI-28978291|uniprotkb:Q8TAI8|uniprotkb:O43154|uniprotkb:Q14DM2|uniprotkb:Q7Z6K8|uniprotkb:Q6ZTV2|uniprotkb:Q96HH7|uniprotkb:Q8IVY5|ensembl:ENSP00000366475 intact:EBI-1052237|uniprotkb:O95186|uniprotkb:A8K2F7|uniprotkb:Q96G53|ensembl:ENSP00000300456 psi-mi:atg2a_human(display_long)|uniprotkb:ATG2A(gene name)|psi-mi:ATG2A(display_short)|uniprotkb:KIAA0404(gene name synonym) psi-mi:s27a4_human(display_long)|uniprotkb:Solute carrier family 27 member 4(gene name synonym)|uniprotkb:SLC27A4(gene name)|psi-mi:SLC27A4(display_short)|uniprotkb:ACSVL4(gene name synonym)|uniprotkb:FATP4(gene name synonym)|uniprotkb:Arachidonate--CoA ligase(gene name synonym)|uniprotkb:Long-chain-fatty-acid--CoA ligase(gene name synonym)|uniprotkb:Very long-chain acyl-CoA synthetase 4(gene name synonym) psi-mi:"MI:0030"(cross-linking study) Tang et al. (2019) imex:IM-28478|pubmed:31412244 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-26443127|imex:IM-28478-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:XP_011543165.1|ensembl:ENSP00000366475|ensembl:ENST00000421419|ensembl:ENSP00000410522|refseq:NP_055919.2|ensembl:ENSG00000110046(gene)|ensembl:ENST00000377264(transcript)|go:"GO:0000045"(autophagosome assembly)|go:"GO:0000407"(phagophore assembly site)|go:"GO:0000422"(autophagy of mitochondrion)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005811"(lipid droplet)|go:"GO:0019898"(extrinsic component of membrane)|go:"GO:0032266"(phosphatidylinositol-3-phosphate binding)|go:"GO:0034045"(phagophore assembly site membrane)|go:"GO:0034727"(piecemeal microautophagy of the nucleus)|go:"GO:0044805"(late nucleophagy)|interpro:IPR015412(ATG2, C-terminal)|interpro:IPR026849|interpro:IPR026854|rcsb pdb:6KLR|go:"GO:0061709"(reticulophagy) refseq:NP_005085.2|ensembl:ENSG00000167114(gene)|ensembl:ENST00000300456(transcript)|go:"GO:0000166"(nucleotide binding)|go:"GO:0001579"(medium-chain fatty acid transport)|go:"GO:0001676"(long-chain fatty acid metabolic process)|go:"GO:0004467"(long-chain fatty acid-CoA ligase activity)|go:"GO:0005324"(long-chain fatty acid transporter activity)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005886"(plasma membrane)|go:"GO:0005902"(microvillus)|go:"GO:0006631"(fatty acid metabolic process)|go:"GO:0007584"(response to nutrient)|go:"GO:0015245"(fatty acid transmembrane transporter activity)|go:"GO:0015908"(fatty acid transport)|go:"GO:0015909"(long-chain fatty acid transport)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0031526"(brush border membrane)|go:"GO:0031957"(very long-chain fatty acid-CoA ligase activity)|go:"GO:0042760"(very long-chain fatty acid catabolic process)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043588"(skin development)|go:"GO:0044381"(glucose import in response to insulin stimulus)|go:"GO:0044539"(long-chain fatty acid import into cell)|go:"GO:0046627"(negative regulation of insulin receptor signaling pathway)|go:"GO:0047676"(arachidonate-CoA ligase activity)|go:"GO:0062003"(negative regulation of all-trans-retinyl-ester hydrolase, 11-cis retinol forming activity)|go:"GO:0090433"(palmitoyl-CoA ligase activity)|go:"GO:0090434"(oleoyl-CoA ligase activity)|go:"GO:0090630"(activation of GTPase activity)|go:"GO:0150104"(transport across blood-brain barrier)|go:"GO:1901480"(oleate transmembrane transporter activity)|go:"GO:1990379"(lipid transport across blood-brain barrier)|interpro:IPR000873(AMP-dependent synthetase and ligase)|interpro:IPR020845|interpro:IPR022272|interpro:IPR025110|interpro:IPR030304|interpro:IPR042099|reactome:R-HSA-5619108|reactome:R-HSA-804914|refseq:XP_016869711.1 - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/10/21 2020/11/06 rogid:RC80jQqKw4ekVFudqz/IunWCEMA9606 rogid:0HD2kZ5IbnIpfLwEK1aFQesLQ289606 rigid:319IsGV1oRp3OLZk5khzgtmEExU false enhanced green fluorescent protein tag:n-n|sufficient binding region:1776-1820 - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q2TAZ0 uniprotkb:O15260 intact:EBI-2514077|intact:EBI-28978291|uniprotkb:Q8TAI8|uniprotkb:O43154|uniprotkb:Q14DM2|uniprotkb:Q7Z6K8|uniprotkb:Q6ZTV2|uniprotkb:Q96HH7|uniprotkb:Q8IVY5|ensembl:ENSP00000366475 intact:EBI-1044848|uniprotkb:O60923|uniprotkb:Q9UNZ0|uniprotkb:Q9UNZ1|uniprotkb:Q5T8U6|ensembl:ENSP00000361057|ensembl:ENSP00000486049|uniprotkb:B7Z6A4 psi-mi:atg2a_human(display_long)|uniprotkb:ATG2A(gene name)|psi-mi:ATG2A(display_short)|uniprotkb:KIAA0404(gene name synonym) psi-mi:surf4_human(display_long)|uniprotkb:SURF4(gene name)|psi-mi:SURF4(display_short)|uniprotkb:SURF-4(gene name synonym) psi-mi:"MI:0030"(cross-linking study) Tang et al. (2019) imex:IM-28478|pubmed:31412244 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-26443127|imex:IM-28478-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:XP_011543165.1|ensembl:ENSP00000366475|ensembl:ENST00000421419|ensembl:ENSP00000410522|refseq:NP_055919.2|ensembl:ENSG00000110046(gene)|ensembl:ENST00000377264(transcript)|go:"GO:0000045"(autophagosome assembly)|go:"GO:0000407"(phagophore assembly site)|go:"GO:0000422"(autophagy of mitochondrion)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005811"(lipid droplet)|go:"GO:0019898"(extrinsic component of membrane)|go:"GO:0032266"(phosphatidylinositol-3-phosphate binding)|go:"GO:0034045"(phagophore assembly site membrane)|go:"GO:0034727"(piecemeal microautophagy of the nucleus)|go:"GO:0044805"(late nucleophagy)|interpro:IPR015412(ATG2, C-terminal)|interpro:IPR026849|interpro:IPR026854|rcsb pdb:6KLR|go:"GO:0061709"(reticulophagy) refseq:NP_149351.1|ensembl:ENSG00000148248(gene)|ensembl:ENSG00000280951(gene)|ensembl:ENST00000629578(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005793"(endoplasmic reticulum-Golgi intermediate compartment)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0007030"(Golgi organization)|go:"GO:0010638"(positive regulation of organelle organization)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030133"(transport vesicle)|go:"GO:0033116"(endoplasmic reticulum-Golgi intermediate compartment membrane)|go:"GO:0035577"(azurophil granule membrane)|interpro:IPR002995(Surfeit locus 4)|mint:O15260|reactome:R-HSA-6798695|reactome:R-HSA-6811434|ensembl:ENST00000371989(transcript)|refseq:NP_001267718.1|refseq:NP_001267721.1 - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/10/21 2020/11/06 rogid:RC80jQqKw4ekVFudqz/IunWCEMA9606 rogid:VEkKSEfWLmSZx209HLRfoMMTzsg9606 rigid:319IsGV1oRp3OLZk5khzgtmEExU false enhanced green fluorescent protein tag:n-n|sufficient binding region:1776-1820 - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q2TAZ0 uniprotkb:Q93050 intact:EBI-2514077|intact:EBI-28978291|uniprotkb:Q8TAI8|uniprotkb:O43154|uniprotkb:Q14DM2|uniprotkb:Q7Z6K8|uniprotkb:Q6ZTV2|uniprotkb:Q96HH7|uniprotkb:Q8IVY5|ensembl:ENSP00000366475 intact:EBI-2891238|ensembl:ENSP00000342951|uniprotkb:Q8N5G7|uniprotkb:Q9NSX0|intact:EBI-4324496|uniprotkb:B7Z3B7 psi-mi:atg2a_human(display_long)|uniprotkb:ATG2A(gene name)|psi-mi:ATG2A(display_short)|uniprotkb:KIAA0404(gene name synonym) psi-mi:vpp1_human(display_long)|uniprotkb:ATP6V0A1(gene name)|psi-mi:ATP6V0A1(display_short)|uniprotkb:ATP6N1(gene name synonym)|uniprotkb:ATP6N1A(gene name synonym)|uniprotkb:VPP1(gene name synonym)|uniprotkb:Vacuolar proton translocating ATPase 116 kDa subunit a isoform 1(gene name synonym)|uniprotkb:Clathrin-coated vesicle/synaptic vesicle proton pump 116 kDa subunit(gene name synonym)|uniprotkb:Vacuolar proton pump subunit 1(gene name synonym)|uniprotkb:Vacuolar adenosine triphosphatase subunit Ac116(gene name synonym) psi-mi:"MI:0030"(cross-linking study) Tang et al. (2019) imex:IM-28478|pubmed:31412244 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-26443127|imex:IM-28478-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:XP_011543165.1|ensembl:ENSP00000366475|ensembl:ENST00000421419|ensembl:ENSP00000410522|refseq:NP_055919.2|ensembl:ENSG00000110046(gene)|ensembl:ENST00000377264(transcript)|go:"GO:0000045"(autophagosome assembly)|go:"GO:0000407"(phagophore assembly site)|go:"GO:0000422"(autophagy of mitochondrion)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005811"(lipid droplet)|go:"GO:0019898"(extrinsic component of membrane)|go:"GO:0032266"(phosphatidylinositol-3-phosphate binding)|go:"GO:0034045"(phagophore assembly site membrane)|go:"GO:0034727"(piecemeal microautophagy of the nucleus)|go:"GO:0044805"(late nucleophagy)|interpro:IPR015412(ATG2, C-terminal)|interpro:IPR026849|interpro:IPR026854|rcsb pdb:6KLR|go:"GO:0061709"(reticulophagy) ensembl:ENSG00000033627(gene)|ensembl:ENST00000343619(transcript)|go:"GO:0000220"(vacuolar proton-transporting V-type ATPase, V0 domain)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0007035"(vacuolar acidification)|go:"GO:0010008"(endosome membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016241"(regulation of macroautophagy)|go:"GO:0016471"(vacuolar proton-transporting V-type ATPase complex)|go:"GO:0016607"(nuclear speck)|go:"GO:0030667"(secretory granule membrane)|go:"GO:0030670"(phagocytic vesicle membrane)|go:"GO:0042470"(melanosome)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0046961"(proton-transporting ATPase activity, rotational mechanism)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051117"(ATPase binding)|go:"GO:0070062"(extracellular exosome)|go:"GO:0101003"(ficolin-1-rich granule membrane)|go:"GO:1901998"(toxin transport)|interpro:IPR002490(ATPase, V0/A0 complex, 116-kDa subunit)|mint:Q93050|rcsb pdb:6WLW|rcsb pdb:6WM2|rcsb pdb:6WM3|rcsb pdb:6WM4|reactome:R-HSA-1222556|reactome:R-HSA-6798695|reactome:R-HSA-77387|interpro:IPR026028|reactome:R-HSA-917977|reactome:R-HSA-983712|refseq:NP_001123492.1|refseq:NP_001123493.1|refseq:NP_005168.2 - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/10/21 2020/11/06 rogid:RC80jQqKw4ekVFudqz/IunWCEMA9606 rogid:3htDhXCA9potj7i32HoA2j3Sfqw9606 rigid:319IsGV1oRp3OLZk5khzgtmEExU false enhanced green fluorescent protein tag:n-n|sufficient binding region:1776-1820 - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q2TAZ0 uniprotkb:Q9BTX1 intact:EBI-2514077|intact:EBI-28978291|uniprotkb:Q8TAI8|uniprotkb:O43154|uniprotkb:Q14DM2|uniprotkb:Q7Z6K8|uniprotkb:Q6ZTV2|uniprotkb:Q96HH7|uniprotkb:Q8IVY5|ensembl:ENSP00000366475 intact:EBI-2552800|ensembl:ENSP00000360483|uniprotkb:Q9NVZ7|uniprotkb:Q9H9T6|uniprotkb:Q9NSG3|uniprotkb:Q9NSG4|uniprotkb:Q8NB76|uniprotkb:B4DHA3|uniprotkb:B4DQQ5|uniprotkb:G3XA81 psi-mi:atg2a_human(display_long)|uniprotkb:ATG2A(gene name)|psi-mi:ATG2A(display_short)|uniprotkb:KIAA0404(gene name synonym) psi-mi:ndc1_human(display_long)|uniprotkb:NDC1(gene name)|psi-mi:NDC1(display_short)|uniprotkb:TMEM48(gene name synonym)|uniprotkb:Transmembrane protein 48(gene name synonym) psi-mi:"MI:0030"(cross-linking study) Tang et al. (2019) imex:IM-28478|pubmed:31412244 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-26443127|imex:IM-28478-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:XP_011543165.1|ensembl:ENSP00000366475|ensembl:ENST00000421419|ensembl:ENSP00000410522|refseq:NP_055919.2|ensembl:ENSG00000110046(gene)|ensembl:ENST00000377264(transcript)|go:"GO:0000045"(autophagosome assembly)|go:"GO:0000407"(phagophore assembly site)|go:"GO:0000422"(autophagy of mitochondrion)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005811"(lipid droplet)|go:"GO:0019898"(extrinsic component of membrane)|go:"GO:0032266"(phosphatidylinositol-3-phosphate binding)|go:"GO:0034045"(phagophore assembly site membrane)|go:"GO:0034727"(piecemeal microautophagy of the nucleus)|go:"GO:0044805"(late nucleophagy)|interpro:IPR015412(ATG2, C-terminal)|interpro:IPR026849|interpro:IPR026854|rcsb pdb:6KLR|go:"GO:0061709"(reticulophagy) refseq:NP_001162023.1|refseq:NP_060557.3|reactome:R-HSA-180746|reactome:R-HSA-180910|reactome:R-HSA-191859|reactome:R-HSA-3108214|reactome:R-HSA-3232142|reactome:R-HSA-3301854|reactome:R-HSA-3371453|reactome:R-HSA-4085377|reactome:R-HSA-4551638|reactome:R-HSA-4570464|reactome:R-HSA-4615885|reactome:R-HSA-5578749|reactome:R-HSA-170822|reactome:R-HSA-5619107|reactome:R-HSA-6784531|reactome:R-HSA-9609690|reactome:R-HSA-9610379|reactome:R-HSA-9615933|ensembl:ENSG00000058804(gene)|ensembl:ENST00000371429(transcript)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0005643"(nuclear pore)|go:"GO:0006999"(nuclear pore organization)|go:"GO:0007129"(homologous chromosome pairing at meiosis)|go:"GO:0007283"(spermatogenesis)|go:"GO:0015031"(protein transport)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0017056"(structural constituent of nuclear pore)|go:"GO:0030674"(protein-macromolecule adaptor activity)|go:"GO:0031965"(nuclear membrane)|go:"GO:0051028"(mRNA transport)|go:"GO:0051292"(nuclear pore complex assembly)|go:"GO:0051664"(nuclear pore localization)|go:"GO:0070762"(nuclear pore transmembrane ring)|interpro:IPR019049|mint:Q9BTX1|reactome:R-HSA-1169408|reactome:R-HSA-159227|reactome:R-HSA-159230|reactome:R-HSA-159231|reactome:R-HSA-159236|reactome:R-HSA-165054|reactome:R-HSA-168271|reactome:R-HSA-168276|reactome:R-HSA-168325|reactome:R-HSA-168333 - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/10/21 2020/11/06 rogid:RC80jQqKw4ekVFudqz/IunWCEMA9606 rogid:0HbFqC4o16ELLTSUfqACs1BD05I9606 rigid:319IsGV1oRp3OLZk5khzgtmEExU false enhanced green fluorescent protein tag:n-n|sufficient binding region:1776-1820 - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q2TAZ0 uniprotkb:P49069 intact:EBI-2514077|intact:EBI-28978291|uniprotkb:Q8TAI8|uniprotkb:O43154|uniprotkb:Q14DM2|uniprotkb:Q7Z6K8|uniprotkb:Q6ZTV2|uniprotkb:Q96HH7|uniprotkb:Q8IVY5|ensembl:ENSP00000366475 intact:EBI-1748958|uniprotkb:A1L3Y3|ensembl:ENSP00000297156 psi-mi:atg2a_human(display_long)|uniprotkb:ATG2A(gene name)|psi-mi:ATG2A(display_short)|uniprotkb:KIAA0404(gene name synonym) psi-mi:camlg_human(display_long)|uniprotkb:CAMLG(gene name)|psi-mi:CAMLG(display_short)|uniprotkb:CAML(gene name synonym)|uniprotkb:Calcium signal-modulating cyclophilin ligand(gene name synonym)|uniprotkb:GET2(gene name synonym) psi-mi:"MI:0030"(cross-linking study) Tang et al. (2019) imex:IM-28478|pubmed:31412244 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-26443127|imex:IM-28478-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:XP_011543165.1|ensembl:ENSP00000366475|ensembl:ENST00000421419|ensembl:ENSP00000410522|refseq:NP_055919.2|ensembl:ENSG00000110046(gene)|ensembl:ENST00000377264(transcript)|go:"GO:0000045"(autophagosome assembly)|go:"GO:0000407"(phagophore assembly site)|go:"GO:0000422"(autophagy of mitochondrion)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005811"(lipid droplet)|go:"GO:0019898"(extrinsic component of membrane)|go:"GO:0032266"(phosphatidylinositol-3-phosphate binding)|go:"GO:0034045"(phagophore assembly site membrane)|go:"GO:0034727"(piecemeal microautophagy of the nucleus)|go:"GO:0044805"(late nucleophagy)|interpro:IPR015412(ATG2, C-terminal)|interpro:IPR026849|interpro:IPR026854|rcsb pdb:6KLR|go:"GO:0061709"(reticulophagy) refseq:NP_001736.1|ensembl:ENSG00000164615(gene)|ensembl:ENST00000297156(transcript)|go:"GO:0001782"(B cell homeostasis)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0006952"(defense response)|go:"GO:0007165"(signal transduction)|go:"GO:0016020"(membrane)|go:"GO:0016192"(vesicle-mediated transport)|go:"GO:0030176"(integral component of endoplasmic reticulum membrane)|go:"GO:0031397"(negative regulation of protein ubiquitination)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032435"(negative regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0043529"(GET complex)|go:"GO:0050821"(protein stabilization)|go:"GO:0050839"(cell adhesion molecule binding)|go:"GO:0071816"(tail-anchored membrane protein insertion into ER membrane)|interpro:IPR016719(Calcium signal-modulating cyclophilin ligand)|rcsb pdb:6SO5|reactome:R-HSA-9609523 - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/10/21 2020/11/06 rogid:RC80jQqKw4ekVFudqz/IunWCEMA9606 rogid:BUKJ1VPumP1iJJnr485rxWzEyK49606 rigid:319IsGV1oRp3OLZk5khzgtmEExU false enhanced green fluorescent protein tag:n-n|sufficient binding region:1776-1820 - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q2TAZ0 uniprotkb:Q9NRG9 intact:EBI-2514077|intact:EBI-28978291|uniprotkb:Q8TAI8|uniprotkb:O43154|uniprotkb:Q14DM2|uniprotkb:Q7Z6K8|uniprotkb:Q6ZTV2|uniprotkb:Q96HH7|uniprotkb:Q8IVY5|ensembl:ENSP00000366475 intact:EBI-3912901|uniprotkb:Q9UG19|uniprotkb:Q9NWI6|uniprotkb:Q5JB47|ensembl:ENSP00000209873 psi-mi:atg2a_human(display_long)|uniprotkb:ATG2A(gene name)|psi-mi:ATG2A(display_short)|uniprotkb:KIAA0404(gene name synonym) psi-mi:aaas_human(display_long)|uniprotkb:AAAS(gene name)|psi-mi:AAAS(display_short)|uniprotkb:ADRACALA(gene name synonym)|uniprotkb:Adracalin(gene name synonym)|uniprotkb:GL003(orf name) psi-mi:"MI:0030"(cross-linking study) Tang et al. (2019) imex:IM-28478|pubmed:31412244 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-26443127|imex:IM-28478-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:XP_011543165.1|ensembl:ENSP00000366475|ensembl:ENST00000421419|ensembl:ENSP00000410522|refseq:NP_055919.2|ensembl:ENSG00000110046(gene)|ensembl:ENST00000377264(transcript)|go:"GO:0000045"(autophagosome assembly)|go:"GO:0000407"(phagophore assembly site)|go:"GO:0000422"(autophagy of mitochondrion)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005811"(lipid droplet)|go:"GO:0019898"(extrinsic component of membrane)|go:"GO:0032266"(phosphatidylinositol-3-phosphate binding)|go:"GO:0034045"(phagophore assembly site membrane)|go:"GO:0034727"(piecemeal microautophagy of the nucleus)|go:"GO:0044805"(late nucleophagy)|interpro:IPR015412(ATG2, C-terminal)|interpro:IPR026849|interpro:IPR026854|rcsb pdb:6KLR|go:"GO:0061709"(reticulophagy) refseq:NP_001166937.1|refseq:NP_056480.1|ensembl:ENSG00000094914(gene)|ensembl:ENST00000209873(transcript)|go:"GO:0000922"(spindle pole)|go:"GO:0001578"(microtubule bundle formation)|go:"GO:0005634"(nucleus)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005643"(nuclear pore)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0006913"(nucleocytoplasmic transport)|go:"GO:0007612"(learning)|go:"GO:0009566"(fertilization)|go:"GO:0015031"(protein transport)|go:"GO:0016020"(membrane)|go:"GO:0031965"(nuclear membrane)|go:"GO:0046822"(regulation of nucleocytoplasmic transport)|go:"GO:0051028"(mRNA transport)|go:"GO:0072686"(mitotic spindle)|go:"GO:0090307"(mitotic spindle assembly)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019775|reactome:R-HSA-1169408|reactome:R-HSA-159227|reactome:R-HSA-159230|reactome:R-HSA-159231|reactome:R-HSA-159236|reactome:R-HSA-165054|reactome:R-HSA-168271|reactome:R-HSA-168276|reactome:R-HSA-168325|reactome:R-HSA-168333|reactome:R-HSA-170822|reactome:R-HSA-180746|reactome:R-HSA-180910|reactome:R-HSA-191859|reactome:R-HSA-3108214|reactome:R-HSA-3232142|reactome:R-HSA-3301854|reactome:R-HSA-3371453|reactome:R-HSA-4085377|reactome:R-HSA-4551638|reactome:R-HSA-4570464|reactome:R-HSA-4615885|reactome:R-HSA-5578749|reactome:R-HSA-5619107|reactome:R-HSA-6784531|reactome:R-HSA-8980692|reactome:R-HSA-9609690|reactome:R-HSA-9610379 - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/10/21 2020/11/06 rogid:RC80jQqKw4ekVFudqz/IunWCEMA9606 rogid:fdOcZ59NldwaQJ6nusjn8GAhszo9606 rigid:319IsGV1oRp3OLZk5khzgtmEExU false enhanced green fluorescent protein tag:n-n|sufficient binding region:1776-1820 - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q2TAZ0 uniprotkb:Q5J8M3 intact:EBI-2514077|intact:EBI-28978291|uniprotkb:Q8TAI8|uniprotkb:O43154|uniprotkb:Q14DM2|uniprotkb:Q7Z6K8|uniprotkb:Q6ZTV2|uniprotkb:Q96HH7|uniprotkb:Q8IVY5|ensembl:ENSP00000366475 intact:EBI-2814031|uniprotkb:Q9P0T9|uniprotkb:Q96KX9|uniprotkb:B4DJQ4|uniprotkb:Q9BUI5|uniprotkb:A8K3A9|ensembl:ENSP00000267750 psi-mi:atg2a_human(display_long)|uniprotkb:ATG2A(gene name)|psi-mi:ATG2A(display_short)|uniprotkb:KIAA0404(gene name synonym) psi-mi:emc4_human(display_long)|uniprotkb:EMC4(gene name)|psi-mi:EMC4(display_short)|uniprotkb:Cell proliferation-inducing gene 17 protein(gene name synonym)|uniprotkb:TMEM85(gene name synonym)|uniprotkb:Transmembrane protein 85(gene name synonym)|uniprotkb:HSPC184(orf name)|uniprotkb:PIG17(orf name) psi-mi:"MI:0030"(cross-linking study) Tang et al. (2019) imex:IM-28478|pubmed:31412244 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-26443127|imex:IM-28478-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:XP_011543165.1|ensembl:ENSP00000366475|ensembl:ENST00000421419|ensembl:ENSP00000410522|refseq:NP_055919.2|ensembl:ENSG00000110046(gene)|ensembl:ENST00000377264(transcript)|go:"GO:0000045"(autophagosome assembly)|go:"GO:0000407"(phagophore assembly site)|go:"GO:0000422"(autophagy of mitochondrion)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005811"(lipid droplet)|go:"GO:0019898"(extrinsic component of membrane)|go:"GO:0032266"(phosphatidylinositol-3-phosphate binding)|go:"GO:0034045"(phagophore assembly site membrane)|go:"GO:0034727"(piecemeal microautophagy of the nucleus)|go:"GO:0044805"(late nucleophagy)|interpro:IPR015412(ATG2, C-terminal)|interpro:IPR026849|interpro:IPR026854|rcsb pdb:6KLR|go:"GO:0061709"(reticulophagy) refseq:NP_001273349.1|refseq:NP_057538.1|ensembl:ENSG00000128463(gene)|ensembl:ENST00000267750(transcript)|go:"GO:0006915"(apoptotic process)|go:"GO:0030176"(integral component of endoplasmic reticulum membrane)|go:"GO:0045050"(protein insertion into ER membrane by stop-transfer membrane-anchor sequence)|go:"GO:0071816"(tail-anchored membrane protein insertion into ER membrane)|go:"GO:0072546"(EMC complex)|interpro:IPR009445(Protein of unknown function DUF1077)|rcsb pdb:6Z3W|rcsb pdb:7ADO|rcsb pdb:7ADP|go:"GO:0016021"(integral component of membrane) - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/10/21 2020/11/06 rogid:RC80jQqKw4ekVFudqz/IunWCEMA9606 rogid:b6qUbq3mJhmXTtZFctD6xd4E1jQ9606 rigid:319IsGV1oRp3OLZk5khzgtmEExU false enhanced green fluorescent protein tag:n-n|sufficient binding region:1776-1820 - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q2TAZ0 uniprotkb:Q96SU4 intact:EBI-2514077|intact:EBI-28978291|uniprotkb:Q8TAI8|uniprotkb:O43154|uniprotkb:Q14DM2|uniprotkb:Q7Z6K8|uniprotkb:Q6ZTV2|uniprotkb:Q96HH7|uniprotkb:Q8IVY5|ensembl:ENSP00000366475 intact:EBI-2511368|ensembl:ENSP00000407168|uniprotkb:Q6IA67|uniprotkb:Q9H9X2|uniprotkb:Q96SK4|uniprotkb:B1AKJ8|uniprotkb:Q5TFC0|uniprotkb:Q8NB17|uniprotkb:Q8TAS8|uniprotkb:D3DQ31|uniprotkb:B3KPQ4|uniprotkb:Q86YQ3 psi-mi:atg2a_human(display_long)|uniprotkb:ATG2A(gene name)|psi-mi:ATG2A(display_short)|uniprotkb:KIAA0404(gene name synonym) psi-mi:osbl9_human(display_long)|uniprotkb:OSBPL9(gene name)|psi-mi:OSBPL9(display_short)|uniprotkb:ORP9(gene name synonym)|uniprotkb:OSBP4(gene name synonym) psi-mi:"MI:0030"(cross-linking study) Tang et al. (2019) imex:IM-28478|pubmed:31412244 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-26443127|imex:IM-28478-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:XP_011543165.1|ensembl:ENSP00000366475|ensembl:ENST00000421419|ensembl:ENSP00000410522|refseq:NP_055919.2|ensembl:ENSG00000110046(gene)|ensembl:ENST00000377264(transcript)|go:"GO:0000045"(autophagosome assembly)|go:"GO:0000407"(phagophore assembly site)|go:"GO:0000422"(autophagy of mitochondrion)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005811"(lipid droplet)|go:"GO:0019898"(extrinsic component of membrane)|go:"GO:0032266"(phosphatidylinositol-3-phosphate binding)|go:"GO:0034045"(phagophore assembly site membrane)|go:"GO:0034727"(piecemeal microautophagy of the nucleus)|go:"GO:0044805"(late nucleophagy)|interpro:IPR015412(ATG2, C-terminal)|interpro:IPR026849|interpro:IPR026854|rcsb pdb:6KLR|go:"GO:0061709"(reticulophagy) ensembl:ENSG00000117859(gene)|ensembl:ENST00000428468(transcript)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0006699"(bile acid biosynthetic process)|go:"GO:0015248"(sterol transporter activity)|go:"GO:0016020"(membrane)|go:"GO:0031902"(late endosome membrane)|go:"GO:0032934"(sterol binding)|go:"GO:0043231"(intracellular membrane-bounded organelle)|interpro:IPR000648(Oxysterol-binding protein)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR018494|interpro:IPR037239|mint:Q96SU4|reactome:R-HSA-192105|refseq:XP_011538905.1|refseq:XP_011538906.1|refseq:NP_078862.4|refseq:NP_683702.1|refseq:NP_683703.1|refseq:NP_683705.1|refseq:NP_683706.3|refseq:NP_683704.2|refseq:NP_683707.3|refseq:XP_006710386.1|refseq:XP_006710387.1|refseq:XP_006710388.1|refseq:XP_006710389.1|refseq:NP_001317509.1|refseq:XP_016855708.1|refseq:XP_016855709.1|refseq:XP_016855710.1 - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/10/21 2020/11/06 rogid:RC80jQqKw4ekVFudqz/IunWCEMA9606 rogid:2XLQ0JD4BEKGoyiwd/63YTmyVlE9606 rigid:319IsGV1oRp3OLZk5khzgtmEExU false enhanced green fluorescent protein tag:n-n|sufficient binding region:1776-1820 - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q2TAZ0 uniprotkb:O43399 intact:EBI-2514077|intact:EBI-28978291|uniprotkb:Q8TAI8|uniprotkb:O43154|uniprotkb:Q14DM2|uniprotkb:Q7Z6K8|uniprotkb:Q6ZTV2|uniprotkb:Q96HH7|uniprotkb:Q8IVY5|ensembl:ENSP00000366475 intact:EBI-782604|uniprotkb:Q5U0E0|uniprotkb:Q5JWU6|uniprotkb:Q9H3Z6|intact:EBI-1043547|uniprotkb:O43398|uniprotkb:Q5JWU5|uniprotkb:Q5JWU8|uniprotkb:E1P5G7|uniprotkb:B4DPJ6|ensembl:ENSP00000343547 psi-mi:atg2a_human(display_long)|uniprotkb:ATG2A(gene name)|psi-mi:ATG2A(display_short)|uniprotkb:KIAA0404(gene name synonym) psi-mi:tpd54_human(display_long)|uniprotkb:Tumor protein D52-like 2(gene name synonym)|uniprotkb:TPD52L2(gene name)|psi-mi:TPD52L2(display_short) psi-mi:"MI:0030"(cross-linking study) Tang et al. (2019) imex:IM-28478|pubmed:31412244 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-26443127|imex:IM-28478-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:XP_011543165.1|ensembl:ENSP00000366475|ensembl:ENST00000421419|ensembl:ENSP00000410522|refseq:NP_055919.2|ensembl:ENSG00000110046(gene)|ensembl:ENST00000377264(transcript)|go:"GO:0000045"(autophagosome assembly)|go:"GO:0000407"(phagophore assembly site)|go:"GO:0000422"(autophagy of mitochondrion)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005811"(lipid droplet)|go:"GO:0019898"(extrinsic component of membrane)|go:"GO:0032266"(phosphatidylinositol-3-phosphate binding)|go:"GO:0034045"(phagophore assembly site membrane)|go:"GO:0034727"(piecemeal microautophagy of the nucleus)|go:"GO:0044805"(late nucleophagy)|interpro:IPR015412(ATG2, C-terminal)|interpro:IPR026849|interpro:IPR026854|rcsb pdb:6KLR|go:"GO:0061709"(reticulophagy) refseq:NP_001230821.1|refseq:NP_003279.2|refseq:NP_955393.1|refseq:NP_955395.1|refseq:NP_955394.1|refseq:NP_955392.1|ensembl:ENSG00000101150(gene)|ensembl:ENST00000346249(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005975"(carbohydrate metabolic process)|go:"GO:0042127"(regulation of cell population proliferation)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0048471"(perinuclear region of cytoplasm)|interpro:IPR007327(Tumor protein D52)|interpro:IPR012341(Six-hairpin glycosidase)|mint:O43399 - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/10/21 2020/11/06 rogid:RC80jQqKw4ekVFudqz/IunWCEMA9606 rogid:asqRlZnmqIzXCJ5TAHjxKcj046g9606 rigid:319IsGV1oRp3OLZk5khzgtmEExU false enhanced green fluorescent protein tag:n-n|sufficient binding region:1776-1820 - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q2TAZ0 uniprotkb:P35610 intact:EBI-2514077|intact:EBI-28978291|uniprotkb:Q8TAI8|uniprotkb:O43154|uniprotkb:Q14DM2|uniprotkb:Q7Z6K8|uniprotkb:Q6ZTV2|uniprotkb:Q96HH7|uniprotkb:Q8IVY5|ensembl:ENSP00000366475 intact:EBI-6621955|ensembl:ENSP00000356591|uniprotkb:A6NC40|uniprotkb:A8K3P4|uniprotkb:A9Z1V7|uniprotkb:B4DU95|uniprotkb:Q5T0X4|uniprotkb:Q8N1E4 psi-mi:atg2a_human(display_long)|uniprotkb:ATG2A(gene name)|psi-mi:ATG2A(display_short)|uniprotkb:KIAA0404(gene name synonym) psi-mi:soat1_human(display_long)|uniprotkb:SOAT1(gene name)|psi-mi:SOAT1(display_short)|uniprotkb:ACACT(gene name synonym)|uniprotkb:ACACT1(gene name synonym)|uniprotkb:ACAT(gene name synonym)|uniprotkb:ACAT1(gene name synonym)|uniprotkb:SOAT(gene name synonym)|uniprotkb:STAT(gene name synonym)|uniprotkb:"Acyl-coenzyme A:cholesterol acyltransferase 1"(gene name synonym)|uniprotkb:Cholesterol acyltransferase 1(gene name synonym) psi-mi:"MI:0030"(cross-linking study) Tang et al. (2019) imex:IM-28478|pubmed:31412244 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-26443127|imex:IM-28478-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:XP_011543165.1|ensembl:ENSP00000366475|ensembl:ENST00000421419|ensembl:ENSP00000410522|refseq:NP_055919.2|ensembl:ENSG00000110046(gene)|ensembl:ENST00000377264(transcript)|go:"GO:0000045"(autophagosome assembly)|go:"GO:0000407"(phagophore assembly site)|go:"GO:0000422"(autophagy of mitochondrion)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005811"(lipid droplet)|go:"GO:0019898"(extrinsic component of membrane)|go:"GO:0032266"(phosphatidylinositol-3-phosphate binding)|go:"GO:0034045"(phagophore assembly site membrane)|go:"GO:0034727"(piecemeal microautophagy of the nucleus)|go:"GO:0044805"(late nucleophagy)|interpro:IPR015412(ATG2, C-terminal)|interpro:IPR026849|interpro:IPR026854|rcsb pdb:6KLR|go:"GO:0061709"(reticulophagy) go:"GO:0010878"(cholesterol storage)|go:"GO:0015485"(cholesterol binding)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0033344"(cholesterol efflux)|go:"GO:0034379"(very-low-density lipoprotein particle assembly)|go:"GO:0034383"(low-density lipoprotein particle clearance)|go:"GO:0034435"(cholesterol esterification)|go:"GO:0034736"(cholesterol O-acyltransferase activity)|go:"GO:0042632"(cholesterol homeostasis)|go:"GO:0042802"(identical protein binding)|go:"GO:0042986"(positive regulation of amyloid precursor protein biosynthetic process)|interpro:IPR004299(Membrane bound O-acyl transferase, MBOAT)|ensembl:ENSG00000057252(gene)|interpro:IPR014371(Sterol O-acyltransferase, ACAT/DAG/ARE types)|interpro:IPR030687|mint:P35610|rcsb pdb:6L47|rcsb pdb:6L48|rcsb pdb:6P2J|rcsb pdb:6P2P|rcsb pdb:6VUM|reactome:R-HSA-8964038|ensembl:ENST00000367619(transcript)|go:"GO:0000062"(fatty-acyl-CoA binding)|go:"GO:0004772"(sterol O-acyltransferase activity)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0008203"(cholesterol metabolic process)|go:"GO:0008374"(O-acyltransferase activity)|go:"GO:0010742"(macrophage derived foam cell differentiation)|refseq:XP_011508213.1|refseq:NP_001239440.1|refseq:NP_001239441.1|refseq:NP_003092.4 - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/10/21 2020/11/06 rogid:RC80jQqKw4ekVFudqz/IunWCEMA9606 rogid:jX8d8x9ZYOdpE2Vg+C5ECuX9zQQ9606 rigid:319IsGV1oRp3OLZk5khzgtmEExU false enhanced green fluorescent protein tag:n-n|sufficient binding region:1776-1820 - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q2TAZ0 uniprotkb:Q13190 intact:EBI-2514077|intact:EBI-28978291|uniprotkb:Q8TAI8|uniprotkb:O43154|uniprotkb:Q14DM2|uniprotkb:Q7Z6K8|uniprotkb:Q6ZTV2|uniprotkb:Q96HH7|uniprotkb:Q8IVY5|ensembl:ENSP00000366475 intact:EBI-714206|uniprotkb:Q5U0D4|uniprotkb:Q7Z3T6|uniprotkb:Q9BUG1|uniprotkb:B2R8T2|ensembl:ENSP00000294179|uniprotkb:F8W8Q9 psi-mi:atg2a_human(display_long)|uniprotkb:ATG2A(gene name)|psi-mi:ATG2A(display_short)|uniprotkb:KIAA0404(gene name synonym) psi-mi:stx5_human(display_long)|uniprotkb:STX5(gene name)|psi-mi:STX5(display_short)|uniprotkb:STX5A(gene name synonym) psi-mi:"MI:0030"(cross-linking study) Tang et al. (2019) imex:IM-28478|pubmed:31412244 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-26443127|imex:IM-28478-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:XP_011543165.1|ensembl:ENSP00000366475|ensembl:ENST00000421419|ensembl:ENSP00000410522|refseq:NP_055919.2|ensembl:ENSG00000110046(gene)|ensembl:ENST00000377264(transcript)|go:"GO:0000045"(autophagosome assembly)|go:"GO:0000407"(phagophore assembly site)|go:"GO:0000422"(autophagy of mitochondrion)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005811"(lipid droplet)|go:"GO:0019898"(extrinsic component of membrane)|go:"GO:0032266"(phosphatidylinositol-3-phosphate binding)|go:"GO:0034045"(phagophore assembly site membrane)|go:"GO:0034727"(piecemeal microautophagy of the nucleus)|go:"GO:0044805"(late nucleophagy)|interpro:IPR015412(ATG2, C-terminal)|interpro:IPR026849|interpro:IPR026854|rcsb pdb:6KLR|go:"GO:0061709"(reticulophagy) refseq:NP_003155.2|ensembl:ENSG00000162236(gene)|ensembl:ENST00000294179(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0000149"(SNARE binding)|go:"GO:0005484"(SNAP receptor activity)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0006906"(vesicle fusion)|go:"GO:0012505"(endomembrane system)|go:"GO:0016021"(integral component of membrane)|go:"GO:0031201"(SNARE complex)|go:"GO:0031982"(vesicle)|go:"GO:0033116"(endoplasmic reticulum-Golgi intermediate compartment membrane)|go:"GO:0034498"(early endosome to Golgi transport)|go:"GO:0042147"(retrograde transport, endosome to Golgi)|go:"GO:0045296"(cadherin binding)|go:"GO:0045732"(positive regulation of protein catabolic process)|go:"GO:0047485"(protein N-terminus binding)|go:"GO:0048278"(vesicle docking)|go:"GO:0048280"(vesicle fusion with Golgi apparatus)|go:"GO:0090166"(Golgi disassembly)|go:"GO:1903358"(regulation of Golgi organization)|interpro:IPR000727(Target SNARE coiled-coil region)|interpro:IPR006012(Syntaxin/epimorphin, conserved site)|interpro:IPR010989(t-SNARE)|interpro:IPR021538|mint:Q13190|rcsb pdb:3EFO|reactome:R-HSA-204005|reactome:R-HSA-5694530|reactome:R-HSA-6807878|reactome:R-HSA-6811438|reactome:R-HSA-8980692|reactome:R-HSA-9013106|go:"GO:0012507"(ER to Golgi transport vesicle membrane)|reactome:R-HSA-9013408|reactome:R-HSA-9609523|refseq:NP_001231595.1|refseq:NP_001317223.1|dip:DIP-56987N - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/10/21 2020/11/06 rogid:RC80jQqKw4ekVFudqz/IunWCEMA9606 rogid:cR4cS695ZWQQ5Bkim9HqmCE0hCE9606 rigid:319IsGV1oRp3OLZk5khzgtmEExU false enhanced green fluorescent protein tag:n-n|sufficient binding region:1776-1820 - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q2TAZ0 uniprotkb:O00186 intact:EBI-2514077|intact:EBI-28978291|uniprotkb:Q8TAI8|uniprotkb:O43154|uniprotkb:Q14DM2|uniprotkb:Q7Z6K8|uniprotkb:Q6ZTV2|uniprotkb:Q96HH7|uniprotkb:Q8IVY5|ensembl:ENSP00000366475 intact:EBI-2803005|uniprotkb:Q86YJ3|uniprotkb:A8K5K7|uniprotkb:Q9UPD7|uniprotkb:A8K269|intact:EBI-3255674|uniprotkb:Q53FW1|ensembl:ENSP00000359025 psi-mi:atg2a_human(display_long)|uniprotkb:ATG2A(gene name)|psi-mi:ATG2A(display_short)|uniprotkb:KIAA0404(gene name synonym) psi-mi:stxb3_human(display_long)|uniprotkb:Platelet Sec1 protein(gene name synonym)|uniprotkb:Protein unc-18 homolog 3(gene name synonym)|uniprotkb:Protein unc-18 homolog C(gene name synonym)|uniprotkb:STXBP3(gene name)|psi-mi:STXBP3(display_short) psi-mi:"MI:0030"(cross-linking study) Tang et al. (2019) imex:IM-28478|pubmed:31412244 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-26443127|imex:IM-28478-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:XP_011543165.1|ensembl:ENSP00000366475|ensembl:ENST00000421419|ensembl:ENSP00000410522|refseq:NP_055919.2|ensembl:ENSG00000110046(gene)|ensembl:ENST00000377264(transcript)|go:"GO:0000045"(autophagosome assembly)|go:"GO:0000407"(phagophore assembly site)|go:"GO:0000422"(autophagy of mitochondrion)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005811"(lipid droplet)|go:"GO:0019898"(extrinsic component of membrane)|go:"GO:0032266"(phosphatidylinositol-3-phosphate binding)|go:"GO:0034045"(phagophore assembly site membrane)|go:"GO:0034727"(piecemeal microautophagy of the nucleus)|go:"GO:0044805"(late nucleophagy)|interpro:IPR015412(ATG2, C-terminal)|interpro:IPR026849|interpro:IPR026854|rcsb pdb:6KLR|go:"GO:0061709"(reticulophagy) refseq:NP_009200.2|ensembl:ENSG00000116266(gene)|ensembl:ENST00000370008(transcript)|go:"GO:0001678"(cellular glucose homeostasis)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006904"(vesicle docking involved in exocytosis)|go:"GO:0007269"(neurotransmitter secretion)|go:"GO:0007420"(brain development)|go:"GO:0016192"(vesicle-mediated transport)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0017075"(syntaxin-1 binding)|go:"GO:0019905"(syntaxin binding)|go:"GO:0022615"(protein to membrane docking)|go:"GO:0030073"(insulin secretion)|go:"GO:0030141"(secretory granule)|go:"GO:0031091"(platelet alpha granule)|go:"GO:0032868"(response to insulin)|go:"GO:0042581"(specific granule)|go:"GO:0043312"(neutrophil degranulation)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045335"(phagocytic vesicle)|go:"GO:0045955"(negative regulation of calcium ion-dependent exocytosis)|go:"GO:0046325"(negative regulation of glucose import)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070527"(platelet aggregation)|go:"GO:0070820"(tertiary granule)|go:"GO:0071346"(cellular response to interferon-gamma)|go:"GO:0098793"(presynapse)|interpro:IPR001619(Sec1-like protein)|interpro:IPR027482|interpro:IPR036045|interpro:IPR043127|interpro:IPR043154|reactome:R-HSA-114516|reactome:R-HSA-1445148 - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/10/21 2020/11/06 rogid:RC80jQqKw4ekVFudqz/IunWCEMA9606 rogid:iDBy0rQnIRdaV5yej86+OU1xcqk9606 rigid:319IsGV1oRp3OLZk5khzgtmEExU false enhanced green fluorescent protein tag:n-n|sufficient binding region:1776-1820 - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q2TAZ0 uniprotkb:P40855 intact:EBI-2514077|intact:EBI-28978291|uniprotkb:Q8TAI8|uniprotkb:O43154|uniprotkb:Q14DM2|uniprotkb:Q7Z6K8|uniprotkb:Q6ZTV2|uniprotkb:Q96HH7|uniprotkb:Q8IVY5|ensembl:ENSP00000366475 intact:EBI-594747|uniprotkb:Q8NI97|intact:EBI-981972|uniprotkb:Q5QNY4|uniprotkb:D3DVE7|ensembl:ENSP00000357051 psi-mi:atg2a_human(display_long)|uniprotkb:ATG2A(gene name)|psi-mi:ATG2A(display_short)|uniprotkb:KIAA0404(gene name synonym) psi-mi:pex19_human(display_long)|uniprotkb:PEX19(gene name)|psi-mi:PEX19(display_short)|uniprotkb:HK33(gene name synonym)|uniprotkb:PXF(gene name synonym)|uniprotkb:OK/SW-cl.22(orf name)|uniprotkb:Peroxin-19(gene name synonym)|uniprotkb:Peroxisomal farnesylated protein(gene name synonym)|uniprotkb:33 kDa housekeeping protein(gene name synonym) psi-mi:"MI:0030"(cross-linking study) Tang et al. (2019) imex:IM-28478|pubmed:31412244 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-26443127|imex:IM-28478-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:XP_011543165.1|ensembl:ENSP00000366475|ensembl:ENST00000421419|ensembl:ENSP00000410522|refseq:NP_055919.2|ensembl:ENSG00000110046(gene)|ensembl:ENST00000377264(transcript)|go:"GO:0000045"(autophagosome assembly)|go:"GO:0000407"(phagophore assembly site)|go:"GO:0000422"(autophagy of mitochondrion)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005811"(lipid droplet)|go:"GO:0019898"(extrinsic component of membrane)|go:"GO:0032266"(phosphatidylinositol-3-phosphate binding)|go:"GO:0034045"(phagophore assembly site membrane)|go:"GO:0034727"(piecemeal microautophagy of the nucleus)|go:"GO:0044805"(late nucleophagy)|interpro:IPR015412(ATG2, C-terminal)|interpro:IPR026849|interpro:IPR026854|rcsb pdb:6KLR|go:"GO:0061709"(reticulophagy) refseq:NP_001180573.1|refseq:NP_002848.1|dip:DIP-24172N|ensembl:ENSG00000162735(gene)|ensembl:ENST00000368072(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005777"(peroxisome)|go:"GO:0005778"(peroxisomal membrane)|go:"GO:0005829"(cytosol)|go:"GO:0006625"(protein targeting to peroxisome)|go:"GO:0007031"(peroxisome organization)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016557"(peroxisome membrane biogenesis)|go:"GO:0016559"(peroxisome fission)|go:"GO:0031526"(brush border membrane)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033328"(peroxisome membrane targeting sequence binding)|go:"GO:0036105"(peroxisome membrane class-1 targeting sequence binding)|go:"GO:0045046"(protein import into peroxisome membrane)|go:"GO:0047485"(protein N-terminus binding)|go:"GO:0050821"(protein stabilization)|go:"GO:0051117"(ATPase binding)|go:"GO:0061077"(chaperone-mediated protein folding)|go:"GO:0072663"(establishment of protein localization to peroxisome)|go:"GO:0140597"(protein carrier chaperone)|go:"GO:1900131"(negative regulation of lipid binding)|interpro:IPR006708(Pex19 protein)|interpro:IPR038322|mint:P40855|rcsb pdb:2W85|rcsb pdb:2WL8|rcsb pdb:3AJB|rcsb pdb:3MK4|rcsb pdb:5LNF|reactome:R-HSA-1369062|reactome:R-HSA-9603798 - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/10/21 2020/11/06 rogid:RC80jQqKw4ekVFudqz/IunWCEMA9606 rogid:yNnX2hPPJ7miGaz2Req0qFn0L189606 rigid:319IsGV1oRp3OLZk5khzgtmEExU false enhanced green fluorescent protein tag:n-n|sufficient binding region:1776-1820 - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q2TAZ0 uniprotkb:Q13586 intact:EBI-2514077|intact:EBI-28978291|uniprotkb:Q8TAI8|uniprotkb:O43154|uniprotkb:Q14DM2|uniprotkb:Q7Z6K8|uniprotkb:Q6ZTV2|uniprotkb:Q96HH7|uniprotkb:Q8IVY5|ensembl:ENSP00000366475 intact:EBI-448878|uniprotkb:Q8N382|ensembl:ENSP00000300737|uniprotkb:E9PQJ4 psi-mi:atg2a_human(display_long)|uniprotkb:ATG2A(gene name)|psi-mi:ATG2A(display_short)|uniprotkb:KIAA0404(gene name synonym) psi-mi:stim1_human(display_long)|uniprotkb:STIM1(gene name)|psi-mi:STIM1(display_short)|uniprotkb:GOK(gene name synonym) psi-mi:"MI:0030"(cross-linking study) Tang et al. (2019) imex:IM-28478|pubmed:31412244 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-26443127|imex:IM-28478-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:XP_011543165.1|ensembl:ENSP00000366475|ensembl:ENST00000421419|ensembl:ENSP00000410522|refseq:NP_055919.2|ensembl:ENSG00000110046(gene)|ensembl:ENST00000377264(transcript)|go:"GO:0000045"(autophagosome assembly)|go:"GO:0000407"(phagophore assembly site)|go:"GO:0000422"(autophagy of mitochondrion)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005811"(lipid droplet)|go:"GO:0019898"(extrinsic component of membrane)|go:"GO:0032266"(phosphatidylinositol-3-phosphate binding)|go:"GO:0034045"(phagophore assembly site membrane)|go:"GO:0034727"(piecemeal microautophagy of the nucleus)|go:"GO:0044805"(late nucleophagy)|interpro:IPR015412(ATG2, C-terminal)|interpro:IPR026849|interpro:IPR026854|rcsb pdb:6KLR|go:"GO:0061709"(reticulophagy) refseq:NP_003147.2|ensembl:ENSG00000167323(gene)|ensembl:ENST00000300737(transcript)|go:"GO:0002020"(protease binding)|go:"GO:0002115"(store-operated calcium entry)|go:"GO:0005246"(calcium channel regulator activity)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005513"(detection of calcium ion)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005874"(microtubule)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006874"(cellular calcium ion homeostasis)|go:"GO:0030176"(integral component of endoplasmic reticulum membrane)|go:"GO:0032237"(activation of store-operated calcium channel activity)|go:"GO:0032541"(cortical endoplasmic reticulum)|go:"GO:0033017"(sarcoplasmic reticulum membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0044853"(plasma membrane raft)|go:"GO:0045762"(positive regulation of adenylate cyclase activity)|go:"GO:0045766"(positive regulation of angiogenesis)|go:"GO:0051010"(microtubule plus-end binding)|go:"GO:0051924"(regulation of calcium ion transport)|go:"GO:0070166"(enamel mineralization)|go:"GO:2001256"(regulation of store-operated calcium entry)|interpro:IPR001660(Sterile alpha motif SAM)|interpro:IPR013761(Sterile alpha motif-type)|interpro:IPR030463|interpro:IPR032393|interpro:IPR037608|interpro:IPR037609|rcsb pdb:2K60|rcsb pdb:2MAJ|rcsb pdb:2MAK|rcsb pdb:3TEQ|rcsb pdb:4O9B|rcsb pdb:6YEL|reactome:R-HSA-139853|reactome:R-HSA-5578775|reactome:R-HSA-983695|refseq:NP_001264891.1|dip:DIP-31121N - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/10/21 2020/11/06 rogid:RC80jQqKw4ekVFudqz/IunWCEMA9606 rogid:GQh8kgCwqrcx7VtJdv63pW1eg/U9606 rigid:319IsGV1oRp3OLZk5khzgtmEExU false enhanced green fluorescent protein tag:n-n|sufficient binding region:1776-1820 - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q2TAZ0 uniprotkb:Q96A49 intact:EBI-2514077|intact:EBI-28978291|uniprotkb:Q8TAI8|uniprotkb:O43154|uniprotkb:Q14DM2|uniprotkb:Q7Z6K8|uniprotkb:Q6ZTV2|uniprotkb:Q96HH7|uniprotkb:Q8IVY5|ensembl:ENSP00000366475 intact:EBI-10770179|uniprotkb:Q68CP1|uniprotkb:Q96C60|uniprotkb:Q96JQ6|uniprotkb:Q96T20|ensembl:ENSP00000369500 psi-mi:atg2a_human(display_long)|uniprotkb:ATG2A(gene name)|psi-mi:ATG2A(display_short)|uniprotkb:KIAA0404(gene name synonym) psi-mi:syap1_human(display_long)|uniprotkb:SYAP1(gene name)|psi-mi:SYAP1(display_short)|uniprotkb:BSD domain-containing signal transducer and Akt interactor protein(gene name synonym)|uniprotkb:PRO3113(orf name) psi-mi:"MI:0030"(cross-linking study) Tang et al. (2019) imex:IM-28478|pubmed:31412244 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-26443127|imex:IM-28478-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:XP_011543165.1|ensembl:ENSP00000366475|ensembl:ENST00000421419|ensembl:ENSP00000410522|refseq:NP_055919.2|ensembl:ENSG00000110046(gene)|ensembl:ENST00000377264(transcript)|go:"GO:0000045"(autophagosome assembly)|go:"GO:0000407"(phagophore assembly site)|go:"GO:0000422"(autophagy of mitochondrion)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005811"(lipid droplet)|go:"GO:0019898"(extrinsic component of membrane)|go:"GO:0032266"(phosphatidylinositol-3-phosphate binding)|go:"GO:0034045"(phagophore assembly site membrane)|go:"GO:0034727"(piecemeal microautophagy of the nucleus)|go:"GO:0044805"(late nucleophagy)|interpro:IPR015412(ATG2, C-terminal)|interpro:IPR026849|interpro:IPR026854|rcsb pdb:6KLR|go:"GO:0061709"(reticulophagy) refseq:NP_116185.2|go:"GO:0030426"(growth cone)|go:"GO:0031234"(extrinsic component of cytoplasmic side of plasma membrane)|go:"GO:0032869"(cellular response to insulin stimulus)|go:"GO:0036120"(cellular response to platelet-derived growth factor stimulus)|go:"GO:0038203"(TORC2 signaling)|go:"GO:0042734"(presynaptic membrane)|go:"GO:0043204"(perikaryon)|go:"GO:0045211"(postsynaptic membrane)|go:"GO:0045600"(positive regulation of fat cell differentiation)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071364"(cellular response to epidermal growth factor stimulus)|go:"GO:0071902"(positive regulation of protein serine/threonine kinase activity)|go:"GO:1990314"(cellular response to insulin-like growth factor stimulus)|interpro:IPR005607(BSD)|interpro:IPR035925|rcsb pdb:1X3A|ensembl:ENSG00000169895(gene)|ensembl:ENST00000380155(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0030154"(cell differentiation)|go:"GO:0030424"(axon)|go:"GO:0030425"(dendrite) - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/10/21 2020/11/06 rogid:RC80jQqKw4ekVFudqz/IunWCEMA9606 rogid:+gHfLl7YaR8geuci2/cAYP8CiKA9606 rigid:319IsGV1oRp3OLZk5khzgtmEExU false enhanced green fluorescent protein tag:n-n|sufficient binding region:1776-1820 - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q2TAZ0 uniprotkb:Q9Y394 intact:EBI-2514077|intact:EBI-28978291|uniprotkb:Q8TAI8|uniprotkb:O43154|uniprotkb:Q14DM2|uniprotkb:Q7Z6K8|uniprotkb:Q6ZTV2|uniprotkb:Q96HH7|uniprotkb:Q8IVY5|ensembl:ENSP00000366475 intact:EBI-1387800|uniprotkb:Q9UKU2|uniprotkb:B2R896|ensembl:ENSP00000216500|ensembl:ENSP00000451882 psi-mi:atg2a_human(display_long)|uniprotkb:ATG2A(gene name)|psi-mi:ATG2A(display_short)|uniprotkb:KIAA0404(gene name synonym) psi-mi:dhrs7_human(display_long)|uniprotkb:DHRS7(gene name)|psi-mi:DHRS7(display_short)|uniprotkb:RETSDR4(gene name synonym)|uniprotkb:SDR34C1(gene name synonym)|uniprotkb:Short chain dehydrogenase/reductase family 34C member 1(gene name synonym)|uniprotkb:CGI-86(orf name)|uniprotkb:UNQ285/PRO3448(orf name)|uniprotkb:DHRS7A(gene name synonym)|uniprotkb:Retinal short-chain dehydrogenase/reductase 4(gene name synonym) psi-mi:"MI:0030"(cross-linking study) Tang et al. (2019) imex:IM-28478|pubmed:31412244 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-26443127|imex:IM-28478-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:XP_011543165.1|ensembl:ENSP00000366475|ensembl:ENST00000421419|ensembl:ENSP00000410522|refseq:NP_055919.2|ensembl:ENSG00000110046(gene)|ensembl:ENST00000377264(transcript)|go:"GO:0000045"(autophagosome assembly)|go:"GO:0000407"(phagophore assembly site)|go:"GO:0000422"(autophagy of mitochondrion)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005811"(lipid droplet)|go:"GO:0019898"(extrinsic component of membrane)|go:"GO:0032266"(phosphatidylinositol-3-phosphate binding)|go:"GO:0034045"(phagophore assembly site membrane)|go:"GO:0034727"(piecemeal microautophagy of the nucleus)|go:"GO:0044805"(late nucleophagy)|interpro:IPR015412(ATG2, C-terminal)|interpro:IPR026849|interpro:IPR026854|rcsb pdb:6KLR|go:"GO:0061709"(reticulophagy) refseq:NP_057113.1|refseq:NP_001309209.1|ensembl:ENSG00000100612(gene)|ensembl:ENST00000216500(transcript)|ensembl:ENST00000557185(transcript)|go:"GO:0016020"(membrane)|go:"GO:0016491"(oxidoreductase activity)|interpro:IPR002347(Glucose/ribitol dehydrogenase)|interpro:IPR020904|interpro:IPR036291 - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/10/21 2020/11/06 rogid:RC80jQqKw4ekVFudqz/IunWCEMA9606 rogid:OcTvozRJMb/lmA0bzcIcNpWIbYE9606 rigid:319IsGV1oRp3OLZk5khzgtmEExU false enhanced green fluorescent protein tag:n-n|sufficient binding region:1776-1820 - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q2TAZ0 uniprotkb:Q6UW68 intact:EBI-2514077|intact:EBI-28978291|uniprotkb:Q8TAI8|uniprotkb:O43154|uniprotkb:Q14DM2|uniprotkb:Q7Z6K8|uniprotkb:Q6ZTV2|uniprotkb:Q96HH7|uniprotkb:Q8IVY5|ensembl:ENSP00000366475 intact:EBI-6269551|ensembl:ENSP00000346954|ensembl:ENSP00000398258|ensembl:ENSP00000465149|ensembl:ENSP00000465483|ensembl:ENSP00000465553|ensembl:ENSP00000466495|ensembl:ENSP00000466986|ensembl:ENSP00000468733 psi-mi:atg2a_human(display_long)|uniprotkb:ATG2A(gene name)|psi-mi:ATG2A(display_short)|uniprotkb:KIAA0404(gene name synonym) psi-mi:tm205_human(display_long)|uniprotkb:TMEM205(gene name)|psi-mi:TMEM205(display_short)|uniprotkb:UNQ501/PRO1018(orf name) psi-mi:"MI:0030"(cross-linking study) Tang et al. (2019) imex:IM-28478|pubmed:31412244 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-26443127|imex:IM-28478-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:XP_011543165.1|ensembl:ENSP00000366475|ensembl:ENST00000421419|ensembl:ENSP00000410522|refseq:NP_055919.2|ensembl:ENSG00000110046(gene)|ensembl:ENST00000377264(transcript)|go:"GO:0000045"(autophagosome assembly)|go:"GO:0000407"(phagophore assembly site)|go:"GO:0000422"(autophagy of mitochondrion)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005811"(lipid droplet)|go:"GO:0019898"(extrinsic component of membrane)|go:"GO:0032266"(phosphatidylinositol-3-phosphate binding)|go:"GO:0034045"(phagophore assembly site membrane)|go:"GO:0034727"(piecemeal microautophagy of the nucleus)|go:"GO:0044805"(late nucleophagy)|interpro:IPR015412(ATG2, C-terminal)|interpro:IPR026849|interpro:IPR026854|rcsb pdb:6KLR|go:"GO:0061709"(reticulophagy) ensembl:ENSG00000105518(gene)|ensembl:ENST00000354882(transcript)|ensembl:ENST00000447337(transcript)|ensembl:ENST00000586590(transcript)|ensembl:ENST00000586956(transcript)|ensembl:ENST00000587948(transcript)|ensembl:ENST00000588560(transcript)|ensembl:ENST00000589555(transcript)|ensembl:ENST00000593256(transcript)|go:"GO:0016021"(integral component of membrane)|interpro:IPR025423|interpro:IPR042623|refseq:NP_001308041.1|refseq:NP_001308042.1|refseq:NP_001308043.1|refseq:XP_005259956.1|refseq:NP_001138888.1|refseq:NP_212133.1|refseq:NP_940938.1 - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/10/21 2020/11/06 rogid:RC80jQqKw4ekVFudqz/IunWCEMA9606 rogid:AUvEOq/WQZo4Mj3eZNL4lp3CYas9606 rigid:319IsGV1oRp3OLZk5khzgtmEExU false enhanced green fluorescent protein tag:n-n|sufficient binding region:1776-1820 - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q2TAZ0 uniprotkb:Q8N2K0 intact:EBI-2514077|intact:EBI-28978291|uniprotkb:Q8TAI8|uniprotkb:O43154|uniprotkb:Q14DM2|uniprotkb:Q7Z6K8|uniprotkb:Q6ZTV2|uniprotkb:Q96HH7|uniprotkb:Q8IVY5|ensembl:ENSP00000366475 intact:EBI-6269657|uniprotkb:A6NED4|uniprotkb:A6NJ90|uniprotkb:A8K450|uniprotkb:B4DE71|uniprotkb:Q5T710|uniprotkb:Q5T711|uniprotkb:Q96CR1|uniprotkb:Q9BX05|uniprotkb:Q9NPX7|uniprotkb:Q9UFV6|ensembl:ENSP00000341408 psi-mi:atg2a_human(display_long)|uniprotkb:ATG2A(gene name)|psi-mi:ATG2A(display_short)|uniprotkb:KIAA0404(gene name synonym) psi-mi:abd12_human(display_long)|uniprotkb:ABHD12(gene name)|psi-mi:ABHD12(display_short)|uniprotkb:C20orf22(gene name synonym)|uniprotkb:Abhydrolase domain-containing protein 12(gene name synonym)|uniprotkb:2-arachidonoylglycerol hydrolase ABHD12(gene name synonym)|uniprotkb:Monoacylglycerol lipase ABHD12(gene name synonym)|uniprotkb:Oxidized phosphatidylserine lipase ABHD12(gene name synonym) psi-mi:"MI:0030"(cross-linking study) Tang et al. (2019) imex:IM-28478|pubmed:31412244 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-26443127|imex:IM-28478-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:XP_011543165.1|ensembl:ENSP00000366475|ensembl:ENST00000421419|ensembl:ENSP00000410522|refseq:NP_055919.2|ensembl:ENSG00000110046(gene)|ensembl:ENST00000377264(transcript)|go:"GO:0000045"(autophagosome assembly)|go:"GO:0000407"(phagophore assembly site)|go:"GO:0000422"(autophagy of mitochondrion)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005811"(lipid droplet)|go:"GO:0019898"(extrinsic component of membrane)|go:"GO:0032266"(phosphatidylinositol-3-phosphate binding)|go:"GO:0034045"(phagophore assembly site membrane)|go:"GO:0034727"(piecemeal microautophagy of the nucleus)|go:"GO:0044805"(late nucleophagy)|interpro:IPR015412(ATG2, C-terminal)|interpro:IPR026849|interpro:IPR026854|rcsb pdb:6KLR|go:"GO:0061709"(reticulophagy) refseq:NP_001035937.1|refseq:NP_056415.1|ensembl:ENSP00000341408|ensembl:ENST00000376542|ensembl:ENSP00000365725|ensembl:ENSG00000100997(gene)|ensembl:ENST00000339157(transcript)|go:"GO:0002084"(protein depalmitoylation)|go:"GO:0004620"(phospholipase activity)|go:"GO:0004622"(lysophospholipase activity)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005886"(plasma membrane)|go:"GO:0006660"(phosphatidylserine catabolic process)|go:"GO:0007628"(adult walking behavior)|go:"GO:0008474"("palmitoyl-(protein) hydrolase activity")|go:"GO:0009395"(phospholipid catabolic process)|go:"GO:0010996"(response to auditory stimulus)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0019369"(arachidonic acid metabolic process)|go:"GO:0032281"(AMPA glutamate receptor complex)|go:"GO:0032839"(dendrite cytoplasm)|go:"GO:0046464"(acylglycerol catabolic process)|go:"GO:0046475"(glycerophospholipid catabolic process)|go:"GO:0047372"(acylglycerol lipase activity)|go:"GO:0050727"(regulation of inflammatory response)|go:"GO:0052651"(monoacylglycerol catabolic process)|interpro:IPR022742|interpro:IPR026605|interpro:IPR029058|mint:Q8N2K0|reactome:R-HSA-426048 - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/10/21 2020/11/06 rogid:RC80jQqKw4ekVFudqz/IunWCEMA9606 rogid:l5KeOxi83Cng20JUGy7ybEtoCPg9606 rigid:319IsGV1oRp3OLZk5khzgtmEExU false enhanced green fluorescent protein tag:n-n|sufficient binding region:1776-1820 - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q2TAZ0 uniprotkb:P21964 intact:EBI-2514077|intact:EBI-28978291|uniprotkb:Q8TAI8|uniprotkb:O43154|uniprotkb:Q14DM2|uniprotkb:Q7Z6K8|uniprotkb:Q6ZTV2|uniprotkb:Q96HH7|uniprotkb:Q8IVY5|ensembl:ENSP00000366475 intact:EBI-372265|uniprotkb:Q6IB07|uniprotkb:Q6ICE6|uniprotkb:A8MPV9|intact:EBI-743305|uniprotkb:Q9BWC7|intact:EBI-11576026|ensembl:ENSP00000354511|ensembl:ENSP00000384654|ensembl:ENSP00000385150|ensembl:ENSP00000385917|ensembl:ENSP00000503583|ensembl:ENSP00000503719|ensembl:ENSP00000504402 psi-mi:atg2a_human(display_long)|uniprotkb:ATG2A(gene name)|psi-mi:ATG2A(display_short)|uniprotkb:KIAA0404(gene name synonym) psi-mi:comt_human(display_long)|uniprotkb:COMT(gene name)|psi-mi:COMT(display_short) psi-mi:"MI:0030"(cross-linking study) Tang et al. (2019) imex:IM-28478|pubmed:31412244 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-26443127|imex:IM-28478-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:XP_011543165.1|ensembl:ENSP00000366475|ensembl:ENST00000421419|ensembl:ENSP00000410522|refseq:NP_055919.2|ensembl:ENSG00000110046(gene)|ensembl:ENST00000377264(transcript)|go:"GO:0000045"(autophagosome assembly)|go:"GO:0000407"(phagophore assembly site)|go:"GO:0000422"(autophagy of mitochondrion)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005811"(lipid droplet)|go:"GO:0019898"(extrinsic component of membrane)|go:"GO:0032266"(phosphatidylinositol-3-phosphate binding)|go:"GO:0034045"(phagophore assembly site membrane)|go:"GO:0034727"(piecemeal microautophagy of the nucleus)|go:"GO:0044805"(late nucleophagy)|interpro:IPR015412(ATG2, C-terminal)|interpro:IPR026849|interpro:IPR026854|rcsb pdb:6KLR|go:"GO:0061709"(reticulophagy) refseq:NP_000745.1|refseq:NP_001128633.1|refseq:NP_001128634.1|refseq:NP_009294.1|refseq:XP_016884083.1|refseq:XP_016884084.1|ensembl:ENSG00000093010(gene)|ensembl:ENST00000361682(transcript)|ensembl:ENST00000403710(transcript)|ensembl:ENST00000406520(transcript)|ensembl:ENST00000407537(transcript)|ensembl:ENST00000676678(transcript)|ensembl:ENST00000678255(transcript)|ensembl:ENST00000678868(transcript)|go:"GO:0000287"(magnesium ion binding)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0007565"(female pregnancy)|go:"GO:0007612"(learning)|go:"GO:0007614"(short-term memory)|go:"GO:0008168"(methyltransferase activity)|go:"GO:0008171"(O-methyltransferase activity)|go:"GO:0008210"(estrogen metabolic process)|go:"GO:0014070"(response to organic cyclic compound)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016036"(cellular response to phosphate starvation)|go:"GO:0016206"(catechol O-methyltransferase activity)|go:"GO:0030424"(axon)|go:"GO:0030425"(dendrite)|go:"GO:0032259"(methylation)|go:"GO:0032496"(response to lipopolysaccharide)|go:"GO:0032502"(developmental process)|go:"GO:0035814"(negative regulation of renal sodium excretion)|go:"GO:0042135"(neurotransmitter catabolic process)|go:"GO:0042417"(dopamine metabolic process)|go:"GO:0042420"(dopamine catabolic process)|go:"GO:0042424"(catecholamine catabolic process)|go:"GO:0042493"|go:"GO:0043197"(dendritic spine)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0043627"(response to estrogen)|go:"GO:0044297"(cell body)|go:"GO:0045211"(postsynaptic membrane)|go:"GO:0045963"(negative regulation of dopamine metabolic process)|go:"GO:0048265"(response to pain)|go:"GO:0048609"(multicellular organismal reproductive process)|go:"GO:0048662"(negative regulation of smooth muscle cell proliferation)|go:"GO:0050668"(positive regulation of homocysteine metabolic process)|go:"GO:0051930"(regulation of sensory perception of pain)|go:"GO:0070062"(extracellular exosome)|go:"GO:0102084"(L-dopa O-methyltransferase activity)|go:"GO:0102938"(orcinol O-methyltransferase activity)|interpro:IPR002935(O-methyltransferase, family 3)|interpro:IPR017128(Catechol O-methyltransferase, eukaryotic)|interpro:IPR029063|mint:P21964|rcsb pdb:3A7E|rcsb pdb:3BWM|rcsb pdb:3BWY|rcsb pdb:4PYI|rcsb pdb:4PYJ|rcsb pdb:4PYK|rcsb pdb:4XUD|rcsb pdb:4XUE|rcsb pdb:5LSA|rcsb pdb:6I3C|rcsb pdb:6I3D|reactome:R-HSA-156581|reactome:R-HSA-379397|reactome:R-HSA-379398|reactome:R-HSA-9679191|rcsb pdb:4XUC - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/10/21 2020/11/06 rogid:RC80jQqKw4ekVFudqz/IunWCEMA9606 rogid:3Fnq8iVqPpOWNX6QQuiNRSsTFN09606 rigid:319IsGV1oRp3OLZk5khzgtmEExU false enhanced green fluorescent protein tag:n-n|sufficient binding region:1776-1820 - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q2TAZ0 uniprotkb:A0FGR8 intact:EBI-2514077|intact:EBI-28978291|uniprotkb:Q8TAI8|uniprotkb:O43154|uniprotkb:Q14DM2|uniprotkb:Q7Z6K8|uniprotkb:Q6ZTV2|uniprotkb:Q96HH7|uniprotkb:Q8IVY5|ensembl:ENSP00000366475 intact:EBI-3184170|uniprotkb:Q9ULJ2|uniprotkb:Q9NW47|uniprotkb:Q69YJ2|uniprotkb:Q6ZVU1|uniprotkb:Q6UKI4|uniprotkb:Q6ZTU0|uniprotkb:Q9BQS0|uniprotkb:A4D229 psi-mi:atg2a_human(display_long)|uniprotkb:ATG2A(gene name)|psi-mi:ATG2A(display_short)|uniprotkb:KIAA0404(gene name synonym) psi-mi:esyt2_human(display_long)|uniprotkb:ESYT2(gene name)|psi-mi:ESYT2(display_short)|uniprotkb:FAM62B(gene name synonym)|uniprotkb:KIAA1228(gene name synonym)|uniprotkb:Chr2Syt(gene name synonym) psi-mi:"MI:0030"(cross-linking study) Tang et al. (2019) imex:IM-28478|pubmed:31412244 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-26443127|imex:IM-28478-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:XP_011543165.1|ensembl:ENSP00000366475|ensembl:ENST00000421419|ensembl:ENSP00000410522|refseq:NP_055919.2|ensembl:ENSG00000110046(gene)|ensembl:ENST00000377264(transcript)|go:"GO:0000045"(autophagosome assembly)|go:"GO:0000407"(phagophore assembly site)|go:"GO:0000422"(autophagy of mitochondrion)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005811"(lipid droplet)|go:"GO:0019898"(extrinsic component of membrane)|go:"GO:0032266"(phosphatidylinositol-3-phosphate binding)|go:"GO:0034045"(phagophore assembly site membrane)|go:"GO:0034727"(piecemeal microautophagy of the nucleus)|go:"GO:0044805"(late nucleophagy)|interpro:IPR015412(ATG2, C-terminal)|interpro:IPR026849|interpro:IPR026854|rcsb pdb:6KLR|go:"GO:0061709"(reticulophagy) go:"GO:0005509"(calcium ion binding)|go:"GO:0005544"(calcium-dependent phospholipid binding)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006869"(lipid transport)|go:"GO:0006897"(endocytosis)|go:"GO:0008429"(phosphatidylethanolamine binding)|go:"GO:0016020"(membrane)|go:"GO:0031210"(phosphatidylcholine binding)|go:"GO:0031227"(intrinsic component of endoplasmic reticulum membrane)|go:"GO:0031234"(extrinsic component of cytoplasmic side of plasma membrane)|go:"GO:0035091"(phosphatidylinositol binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0044232"(organelle membrane contact site)|go:"GO:0045296"(cadherin binding)|go:"GO:0061817"(endoplasmic reticulum-plasma membrane tethering)|go:"GO:0140268"(endoplasmic reticulum-plasma membrane contact site)|interpro:IPR000008(C2 calcium-dependent membrane targeting)|interpro:IPR031468|interpro:IPR035892|go:"GO:0005789"(endoplasmic reticulum membrane)|interpro:IPR037733|interpro:IPR037749|interpro:IPR037752|interpro:IPR039010|rcsb pdb:2DMG|rcsb pdb:4NPJ|rcsb pdb:4NPK|rcsb pdb:4P42|reactome:R-HSA-1660662|refseq:NP_065779.1|mint:A0FGR8|dip:DIP-61039N - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/10/21 2020/11/06 rogid:RC80jQqKw4ekVFudqz/IunWCEMA9606 rogid:mOkUWt8oia02xtJYM6gQz3tsav89606 rigid:319IsGV1oRp3OLZk5khzgtmEExU false enhanced green fluorescent protein tag:n-n|sufficient binding region:1776-1820 - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q2TAZ0 uniprotkb:Q8N2G8 intact:EBI-2514077|intact:EBI-28978291|uniprotkb:Q8TAI8|uniprotkb:O43154|uniprotkb:Q14DM2|uniprotkb:Q7Z6K8|uniprotkb:Q6ZTV2|uniprotkb:Q96HH7|uniprotkb:Q8IVY5|ensembl:ENSP00000366475 intact:EBI-10985637|uniprotkb:B4DQS4|uniprotkb:E9PDB5|uniprotkb:Q9BXM6|ensembl:ENSP00000301671|ensembl:ENSP00000467585 psi-mi:atg2a_human(display_long)|uniprotkb:ATG2A(gene name)|psi-mi:ATG2A(display_short)|uniprotkb:KIAA0404(gene name synonym) psi-mi:ghdc_human(display_long)|uniprotkb:GHDC(gene name)|psi-mi:GHDC(display_short)|uniprotkb:D11LGP1E(gene name synonym)|uniprotkb:LGP1(gene name synonym) psi-mi:"MI:0030"(cross-linking study) Tang et al. (2019) imex:IM-28478|pubmed:31412244 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-26443127|imex:IM-28478-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:XP_011543165.1|ensembl:ENSP00000366475|ensembl:ENST00000421419|ensembl:ENSP00000410522|refseq:NP_055919.2|ensembl:ENSG00000110046(gene)|ensembl:ENST00000377264(transcript)|go:"GO:0000045"(autophagosome assembly)|go:"GO:0000407"(phagophore assembly site)|go:"GO:0000422"(autophagy of mitochondrion)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005811"(lipid droplet)|go:"GO:0019898"(extrinsic component of membrane)|go:"GO:0032266"(phosphatidylinositol-3-phosphate binding)|go:"GO:0034045"(phagophore assembly site membrane)|go:"GO:0034727"(piecemeal microautophagy of the nucleus)|go:"GO:0044805"(late nucleophagy)|interpro:IPR015412(ATG2, C-terminal)|interpro:IPR026849|interpro:IPR026854|rcsb pdb:6KLR|go:"GO:0061709"(reticulophagy) refseq:NP_001136095.1|refseq:NP_115873.1|ensembl:ENSG00000167925(gene)|ensembl:ENST00000301671(transcript)|ensembl:ENST00000587427(transcript)|go:"GO:0005576"(extracellular region)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0016020"(membrane)|go:"GO:0016881"(acid-amino acid ligase activity)|go:"GO:0034774"(secretory granule lumen)|go:"GO:0035580"(specific granule lumen)|interpro:IPR004993(GH3 auxin-responsive promoter)|reactome:R-HSA-6798695 - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/10/21 2020/11/06 rogid:RC80jQqKw4ekVFudqz/IunWCEMA9606 rogid:AlZkawSGl/YLF3onfXtqK0vWf4k9606 rigid:319IsGV1oRp3OLZk5khzgtmEExU false enhanced green fluorescent protein tag:n-n|sufficient binding region:1776-1820 - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q2TAZ0 uniprotkb:Q9NX47 intact:EBI-2514077|intact:EBI-28978291|uniprotkb:Q8TAI8|uniprotkb:O43154|uniprotkb:Q14DM2|uniprotkb:Q7Z6K8|uniprotkb:Q6ZTV2|uniprotkb:Q96HH7|uniprotkb:Q8IVY5|ensembl:ENSP00000366475 intact:EBI-2341610|ensembl:ENSP00000351813 psi-mi:atg2a_human(display_long)|uniprotkb:ATG2A(gene name)|psi-mi:ATG2A(display_short)|uniprotkb:KIAA0404(gene name synonym) psi-mi:marh5_human(display_long)|uniprotkb:MARCH5(gene name synonym)|uniprotkb:Membrane-associated RING finger protein 5(gene name synonym)|uniprotkb:Membrane-associated RING-CH protein V(gene name synonym)|uniprotkb:Mitochondrial ubiquitin ligase(gene name synonym)|uniprotkb:RING finger protein 153(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase MARCHF5(gene name synonym)|uniprotkb:MARCHF5(gene name)|psi-mi:MARCHF5(display_short)|uniprotkb:RNF153(gene name synonym) psi-mi:"MI:0030"(cross-linking study) Tang et al. (2019) imex:IM-28478|pubmed:31412244 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-26443127|imex:IM-28478-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:XP_011543165.1|ensembl:ENSP00000366475|ensembl:ENST00000421419|ensembl:ENSP00000410522|refseq:NP_055919.2|ensembl:ENSG00000110046(gene)|ensembl:ENST00000377264(transcript)|go:"GO:0000045"(autophagosome assembly)|go:"GO:0000407"(phagophore assembly site)|go:"GO:0000422"(autophagy of mitochondrion)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005811"(lipid droplet)|go:"GO:0019898"(extrinsic component of membrane)|go:"GO:0032266"(phosphatidylinositol-3-phosphate binding)|go:"GO:0034045"(phagophore assembly site membrane)|go:"GO:0034727"(piecemeal microautophagy of the nucleus)|go:"GO:0044805"(late nucleophagy)|interpro:IPR015412(ATG2, C-terminal)|interpro:IPR026849|interpro:IPR026854|rcsb pdb:6KLR|go:"GO:0061709"(reticulophagy) refseq:NP_060294.1|ensembl:ENSG00000198060(gene)|ensembl:ENST00000358935(transcript)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0005739"(mitochondrion)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0008270"(zinc ion binding)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0051020"(GTPase binding)|go:"GO:0051865"(protein autoubiquitination)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0070585"(protein localization to mitochondrion)|go:"GO:0090140"(regulation of mitochondrial fission)|go:"GO:0090141"(positive regulation of mitochondrial fission)|go:"GO:0090344"(negative regulation of cell aging)|interpro:IPR011016(Zinc finger, variant RING-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|mint:Q9NX47 - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/10/21 2020/11/06 rogid:RC80jQqKw4ekVFudqz/IunWCEMA9606 rogid:/w+L/oINlKM5ZSm1OkI+R+8PxXg9606 rigid:319IsGV1oRp3OLZk5khzgtmEExU false enhanced green fluorescent protein tag:n-n|sufficient binding region:1776-1820 - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q2TAZ0 uniprotkb:O95487 intact:EBI-2514077|intact:EBI-28978291|uniprotkb:Q8TAI8|uniprotkb:O43154|uniprotkb:Q14DM2|uniprotkb:Q7Z6K8|uniprotkb:Q6ZTV2|uniprotkb:Q96HH7|uniprotkb:Q8IVY5|ensembl:ENSP00000366475 intact:EBI-81101|uniprotkb:Q0VG08|ensembl:ENSP00000265175|uniprotkb:B7ZKN4|uniprotkb:B7ZKM8 psi-mi:atg2a_human(display_long)|uniprotkb:ATG2A(gene name)|psi-mi:ATG2A(display_short)|uniprotkb:KIAA0404(gene name synonym) psi-mi:sc24b_human(display_long)|uniprotkb:SEC24B(gene name)|psi-mi:SEC24B(display_short)|uniprotkb:SEC24-related protein B(gene name synonym) psi-mi:"MI:0030"(cross-linking study) Tang et al. (2019) imex:IM-28478|pubmed:31412244 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-26443127|imex:IM-28478-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:XP_011543165.1|ensembl:ENSP00000366475|ensembl:ENST00000421419|ensembl:ENSP00000410522|refseq:NP_055919.2|ensembl:ENSG00000110046(gene)|ensembl:ENST00000377264(transcript)|go:"GO:0000045"(autophagosome assembly)|go:"GO:0000407"(phagophore assembly site)|go:"GO:0000422"(autophagy of mitochondrion)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005811"(lipid droplet)|go:"GO:0019898"(extrinsic component of membrane)|go:"GO:0032266"(phosphatidylinositol-3-phosphate binding)|go:"GO:0034045"(phagophore assembly site membrane)|go:"GO:0034727"(piecemeal microautophagy of the nucleus)|go:"GO:0044805"(late nucleophagy)|interpro:IPR015412(ATG2, C-terminal)|interpro:IPR026849|interpro:IPR026854|rcsb pdb:6KLR|go:"GO:0061709"(reticulophagy) refseq:NP_001036199.1|refseq:NP_006314.2|ensembl:ENSG00000138802(gene)|ensembl:ENST00000265175(transcript)|go:"GO:0000149"(SNARE binding)|go:"GO:0001843"(neural tube closure)|go:"GO:0003151"(outflow tract morphogenesis)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005829"(cytosol)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0008270"(zinc ion binding)|go:"GO:0012507"(ER to Golgi transport vesicle membrane)|go:"GO:0030127"(COPII vesicle coat)|go:"GO:0035909"(aorta morphogenesis)|go:"GO:0060088"(auditory receptor cell stereocilium organization)|go:"GO:0060463"(lung lobe morphogenesis)|go:"GO:0060982"(coronary artery morphogenesis)|go:"GO:0061156"(pulmonary artery morphogenesis)|go:"GO:0070971"(endoplasmic reticulum exit site)|go:"GO:0090110"(COPII-coated vesicle cargo loading)|go:"GO:0090178"(regulation of establishment of planar polarity involved in neural tube closure)|go:"GO:1901301"(regulation of cargo loading into COPII-coated vesicle)|interpro:IPR006895(Zinc finger, Sec23/Sec24-type)|interpro:IPR006896(Sec23/Sec24 trunk region)|interpro:IPR006900(Sec23/Sec24 helical region)|interpro:IPR007123(Gelsolin region)|interpro:IPR012990(Sec23/Sec24 beta-sandwich)|interpro:IPR029006|interpro:IPR036174|interpro:IPR036175|interpro:IPR036180|interpro:IPR036465|interpro:IPR041742|rcsb pdb:3EH1|go:"GO:0021747"(cochlear nucleus development)|reactome:R-HSA-204005|reactome:R-HSA-2132295|reactome:R-HSA-5694530|reactome:R-HSA-983170|reactome:R-HSA-1655829|refseq:NP_001305014.1|refseq:NP_001305015.1|refseq:NP_001287742.1 - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/10/21 2020/11/06 rogid:RC80jQqKw4ekVFudqz/IunWCEMA9606 rogid:ruwQ7b7xFHTKb3ckyAcWvWePc+k9606 rigid:319IsGV1oRp3OLZk5khzgtmEExU false enhanced green fluorescent protein tag:n-n|sufficient binding region:1776-1820 - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q2TAZ0 uniprotkb:Q9HD20 intact:EBI-2514077|intact:EBI-28978291|uniprotkb:Q8TAI8|uniprotkb:O43154|uniprotkb:Q14DM2|uniprotkb:Q7Z6K8|uniprotkb:Q6ZTV2|uniprotkb:Q96HH7|uniprotkb:Q8IVY5|ensembl:ENSP00000366475 intact:EBI-3940599|uniprotkb:B3KTA7|uniprotkb:B3KPJ2|uniprotkb:Q9H6C6|ensembl:ENSP00000349877|uniprotkb:Q6NT90|uniprotkb:Q6ZMG7 psi-mi:atg2a_human(display_long)|uniprotkb:ATG2A(gene name)|psi-mi:ATG2A(display_short)|uniprotkb:KIAA0404(gene name synonym) psi-mi:at131_human(display_long)|uniprotkb:ATP13A1(gene name)|psi-mi:ATP13A1(display_short)|uniprotkb:ATP13A(gene name synonym)|uniprotkb:KIAA1825(gene name synonym)|uniprotkb:CGI-152(orf name)|uniprotkb:Endoplasmic reticulum P5A-ATPase(gene name synonym) psi-mi:"MI:0030"(cross-linking study) Tang et al. (2019) imex:IM-28478|pubmed:31412244 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-26443127|imex:IM-28478-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:XP_011543165.1|ensembl:ENSP00000366475|ensembl:ENST00000421419|ensembl:ENSP00000410522|refseq:NP_055919.2|ensembl:ENSG00000110046(gene)|ensembl:ENST00000377264(transcript)|go:"GO:0000045"(autophagosome assembly)|go:"GO:0000407"(phagophore assembly site)|go:"GO:0000422"(autophagy of mitochondrion)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005811"(lipid droplet)|go:"GO:0019898"(extrinsic component of membrane)|go:"GO:0032266"(phosphatidylinositol-3-phosphate binding)|go:"GO:0034045"(phagophore assembly site membrane)|go:"GO:0034727"(piecemeal microautophagy of the nucleus)|go:"GO:0044805"(late nucleophagy)|interpro:IPR015412(ATG2, C-terminal)|interpro:IPR026849|interpro:IPR026854|rcsb pdb:6KLR|go:"GO:0061709"(reticulophagy) ensembl:ENSG00000105726(gene)|ensembl:ENST00000357324(transcript)|go:"GO:0005524"(ATP binding)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006874"(cellular calcium ion homeostasis)|go:"GO:0015031"(protein transport)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0034220"(ion transmembrane transport)|go:"GO:0046872"(metal ion binding)|go:"GO:0140567"(transmembrane protein dislocase activity)|go:"GO:0140569"(extraction of mislocalized protein from ER membrane)|interpro:IPR001757(ATPase, P-type, K/Mg/Cd/Cu/Zn/Na/Ca/Na/H-transporter)|interpro:IPR006544("P-type ATPase of unknown pump specificity (type V)")|interpro:IPR008250(E1-E2 ATPase-associated region)|interpro:IPR018303|interpro:IPR023214|interpro:IPR023298|interpro:IPR023299|interpro:IPR036412|interpro:IPR044492|mint:Q9HD20|reactome:R-HSA-936837|go:"GO:0015410"(ABC-type manganese transporter activity)|refseq:NP_065143.2 - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/10/21 2020/11/06 rogid:RC80jQqKw4ekVFudqz/IunWCEMA9606 rogid:p4PEgZhH5QhoHI+InDMbLvdIBP09606 rigid:319IsGV1oRp3OLZk5khzgtmEExU false enhanced green fluorescent protein tag:n-n|sufficient binding region:1776-1820 - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q2TAZ0 uniprotkb:O43402 intact:EBI-2514077|intact:EBI-28978291|uniprotkb:Q8TAI8|uniprotkb:O43154|uniprotkb:Q14DM2|uniprotkb:Q7Z6K8|uniprotkb:Q6ZTV2|uniprotkb:Q96HH7|uniprotkb:Q8IVY5|ensembl:ENSP00000366475 intact:EBI-741841|ensembl:ENSP00000253457|uniprotkb:C9JB21 psi-mi:atg2a_human(display_long)|uniprotkb:ATG2A(gene name)|psi-mi:ATG2A(display_short)|uniprotkb:KIAA0404(gene name synonym) psi-mi:emc8_human(display_long)|uniprotkb:EMC8(gene name)|psi-mi:EMC8(display_short)|uniprotkb:C16orf2(gene name synonym)|uniprotkb:C16orf4(gene name synonym)|uniprotkb:COX4AL(gene name synonym)|uniprotkb:COX4NB(gene name synonym)|uniprotkb:FAM158B(gene name synonym)|uniprotkb:NOC4(gene name synonym)|uniprotkb:Neighbor of COX4(gene name synonym)|uniprotkb:Protein FAM158B(gene name synonym) psi-mi:"MI:0030"(cross-linking study) Tang et al. (2019) imex:IM-28478|pubmed:31412244 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-26443127|imex:IM-28478-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:XP_011543165.1|ensembl:ENSP00000366475|ensembl:ENST00000421419|ensembl:ENSP00000410522|refseq:NP_055919.2|ensembl:ENSG00000110046(gene)|ensembl:ENST00000377264(transcript)|go:"GO:0000045"(autophagosome assembly)|go:"GO:0000407"(phagophore assembly site)|go:"GO:0000422"(autophagy of mitochondrion)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005811"(lipid droplet)|go:"GO:0019898"(extrinsic component of membrane)|go:"GO:0032266"(phosphatidylinositol-3-phosphate binding)|go:"GO:0034045"(phagophore assembly site membrane)|go:"GO:0034727"(piecemeal microautophagy of the nucleus)|go:"GO:0044805"(late nucleophagy)|interpro:IPR015412(ATG2, C-terminal)|interpro:IPR026849|interpro:IPR026854|rcsb pdb:6KLR|go:"GO:0061709"(reticulophagy) refseq:NP_006058.1|ensembl:ENSG00000131148(gene)|ensembl:ENST00000253457(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0016020"(membrane)|go:"GO:0045050"(protein insertion into ER membrane by stop-transfer membrane-anchor sequence)|go:"GO:0071816"(tail-anchored membrane protein insertion into ER membrane)|go:"GO:0072546"(EMC complex)|interpro:IPR005366(Protein of unknown function UPF0172)|interpro:IPR037518|rcsb pdb:6WW7|rcsb pdb:7ADO|rcsb pdb:7ADP|refseq:NP_001135760.1 - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/10/21 2020/11/06 rogid:RC80jQqKw4ekVFudqz/IunWCEMA9606 rogid:cGQFR1ZU2L/KgikqLELVUzplhTU9606 rigid:319IsGV1oRp3OLZk5khzgtmEExU false enhanced green fluorescent protein tag:n-n|sufficient binding region:1776-1820 - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q2TAZ0 uniprotkb:O15270 intact:EBI-2514077|intact:EBI-28978291|uniprotkb:Q8TAI8|uniprotkb:O43154|uniprotkb:Q14DM2|uniprotkb:Q7Z6K8|uniprotkb:Q6ZTV2|uniprotkb:Q96HH7|uniprotkb:Q8IVY5|ensembl:ENSP00000366475 intact:EBI-766136|uniprotkb:Q16685|ensembl:ENSP00000216484 psi-mi:atg2a_human(display_long)|uniprotkb:ATG2A(gene name)|psi-mi:ATG2A(display_short)|uniprotkb:KIAA0404(gene name synonym) psi-mi:sptc2_human(display_long)|uniprotkb:Serine-palmitoyl-CoA transferase 2(gene name synonym)|uniprotkb:Long chain base biosynthesis protein 2(gene name synonym)|uniprotkb:SPTLC2(gene name)|psi-mi:SPTLC2(display_short)|uniprotkb:KIAA0526(gene name synonym)|uniprotkb:LCB2(gene name synonym)|uniprotkb:Long chain base biosynthesis protein 2a(gene name synonym) psi-mi:"MI:0030"(cross-linking study) Tang et al. (2019) imex:IM-28478|pubmed:31412244 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-26443127|imex:IM-28478-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:XP_011543165.1|ensembl:ENSP00000366475|ensembl:ENST00000421419|ensembl:ENSP00000410522|refseq:NP_055919.2|ensembl:ENSG00000110046(gene)|ensembl:ENST00000377264(transcript)|go:"GO:0000045"(autophagosome assembly)|go:"GO:0000407"(phagophore assembly site)|go:"GO:0000422"(autophagy of mitochondrion)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005811"(lipid droplet)|go:"GO:0019898"(extrinsic component of membrane)|go:"GO:0032266"(phosphatidylinositol-3-phosphate binding)|go:"GO:0034045"(phagophore assembly site membrane)|go:"GO:0034727"(piecemeal microautophagy of the nucleus)|go:"GO:0044805"(late nucleophagy)|interpro:IPR015412(ATG2, C-terminal)|interpro:IPR026849|interpro:IPR026854|rcsb pdb:6KLR|go:"GO:0061709"(reticulophagy) refseq:NP_004854.1|dip:DIP-34604N|ensembl:ENSG00000100596(gene)|ensembl:ENST00000216484(transcript)|go:"GO:0004758"(serine C-palmitoyltransferase activity)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006686"(sphingomyelin biosynthetic process)|go:"GO:0016021"(integral component of membrane)|go:"GO:0017059"(serine C-palmitoyltransferase complex)|go:"GO:0030148"(sphingolipid biosynthetic process)|go:"GO:0030170"(pyridoxal phosphate binding)|go:"GO:0046511"(sphinganine biosynthetic process)|go:"GO:0046512"(sphingosine biosynthetic process)|go:"GO:0046513"(ceramide biosynthetic process)|go:"GO:0060612"(adipose tissue development)|go:"GO:1904504"(positive regulation of lipophagy)|interpro:IPR001917(Aminotransferase, class-II, pyridoxal-phosphate binding site)|interpro:IPR004839(Aminotransferase, class I and II)|interpro:IPR015421(Pyridoxal phosphate-dependent transferase, major region, subdomain 1)|interpro:IPR015422(Pyridoxal phosphate-dependent transferase, major region, subdomain 2)|interpro:IPR015424(Pyridoxal phosphate-dependent transferase, major region)|mint:O15270|rcsb pdb:6M4N|rcsb pdb:6M4O|rcsb pdb:7CQI|rcsb pdb:7CQK|rcsb pdb:7K0I|rcsb pdb:7K0J|rcsb pdb:7K0K|rcsb pdb:7K0L|rcsb pdb:7K0M|rcsb pdb:7K0N|rcsb pdb:7K0O|rcsb pdb:7K0P|rcsb pdb:7K0Q|reactome:R-HSA-1660661 - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/10/21 2020/11/06 rogid:RC80jQqKw4ekVFudqz/IunWCEMA9606 rogid:9Y8pOwwEej+jqblWkGS0ixnNHLo9606 rigid:319IsGV1oRp3OLZk5khzgtmEExU false enhanced green fluorescent protein tag:n-n|sufficient binding region:1776-1820 - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q2TAZ0 uniprotkb:Q9HD45 intact:EBI-2514077|intact:EBI-28978291|uniprotkb:Q8TAI8|uniprotkb:O43154|uniprotkb:Q14DM2|uniprotkb:Q7Z6K8|uniprotkb:Q6ZTV2|uniprotkb:Q96HH7|uniprotkb:Q8IVY5|ensembl:ENSP00000366475 intact:EBI-2814047|uniprotkb:Q9NWL8|uniprotkb:Q5TB57|uniprotkb:Q9UHW8|uniprotkb:Q6UWE7|uniprotkb:Q9P0G9|ensembl:ENSP00000360184 psi-mi:atg2a_human(display_long)|uniprotkb:ATG2A(gene name)|psi-mi:ATG2A(display_short)|uniprotkb:KIAA0404(gene name synonym) psi-mi:tm9s3_human(display_long)|uniprotkb:TM9SF3(gene name)|psi-mi:TM9SF3(display_short)|uniprotkb:SMBP(gene name synonym)|uniprotkb:EP70-P-iso(gene name synonym)|uniprotkb:SM-11044-binding protein(gene name synonym)|uniprotkb:UNQ245/PRO282(orf name) psi-mi:"MI:0030"(cross-linking study) Tang et al. (2019) imex:IM-28478|pubmed:31412244 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-26443127|imex:IM-28478-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:XP_011543165.1|ensembl:ENSP00000366475|ensembl:ENST00000421419|ensembl:ENSP00000410522|refseq:NP_055919.2|ensembl:ENSG00000110046(gene)|ensembl:ENST00000377264(transcript)|go:"GO:0000045"(autophagosome assembly)|go:"GO:0000407"(phagophore assembly site)|go:"GO:0000422"(autophagy of mitochondrion)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005811"(lipid droplet)|go:"GO:0019898"(extrinsic component of membrane)|go:"GO:0032266"(phosphatidylinositol-3-phosphate binding)|go:"GO:0034045"(phagophore assembly site membrane)|go:"GO:0034727"(piecemeal microautophagy of the nucleus)|go:"GO:0044805"(late nucleophagy)|interpro:IPR015412(ATG2, C-terminal)|interpro:IPR026849|interpro:IPR026854|rcsb pdb:6KLR|go:"GO:0061709"(reticulophagy) refseq:NP_064508.3|ensembl:ENSG00000077147(gene)|ensembl:ENST00000371142(transcript)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0072657"(protein localization to membrane)|interpro:IPR004240("Nonaspanin (TM9SF)")|mint:Q9HD45 - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/10/21 2020/11/06 rogid:RC80jQqKw4ekVFudqz/IunWCEMA9606 rogid:/9Z/a+36wE2FTbIyQ/zWPPGo9Rs9606 rigid:319IsGV1oRp3OLZk5khzgtmEExU false enhanced green fluorescent protein tag:n-n|sufficient binding region:1776-1820 - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q2TAZ0 uniprotkb:O60271 intact:EBI-2514077|intact:EBI-28978291|uniprotkb:Q8TAI8|uniprotkb:O43154|uniprotkb:Q14DM2|uniprotkb:Q7Z6K8|uniprotkb:Q6ZTV2|uniprotkb:Q96HH7|uniprotkb:Q8IVY5|ensembl:ENSP00000366475 intact:EBI-1023301|uniprotkb:O60905|uniprotkb:Q3KQU8|uniprotkb:Q3MKM7|uniprotkb:Q86WC7|uniprotkb:Q86WC8|uniprotkb:Q8IZX7|uniprotkb:Q96II0|uniprotkb:Q9H811|uniprotkb:A8MSX0|uniprotkb:B4DHH2|uniprotkb:A6H8U5|intact:EBI-2560890|ensembl:ENSP00000262013 psi-mi:atg2a_human(display_long)|uniprotkb:ATG2A(gene name)|psi-mi:ATG2A(display_short)|uniprotkb:KIAA0404(gene name synonym) psi-mi:jip4_human(display_long)|uniprotkb:JNK-associated leucine-zipper protein(gene name synonym)|uniprotkb:Sperm-associated antigen 9(gene name synonym)|uniprotkb:Mitogen-activated protein kinase 8-interacting protein 4(gene name synonym)|uniprotkb:Human lung cancer oncogene 6 protein(gene name synonym)|uniprotkb:Proliferation-inducing protein 6(gene name synonym)|uniprotkb:Sperm-specific protein(gene name synonym)|uniprotkb:Sperm surface protein(gene name synonym)|uniprotkb:Protein highly expressed in testis(gene name synonym)|uniprotkb:Sunday driver 1(gene name synonym)|uniprotkb:Cancer/testis antigen 89(gene name synonym)|uniprotkb:HLC6(orf name)|uniprotkb:SPAG9(gene name)|psi-mi:SPAG9(display_short)|uniprotkb:HSS(gene name synonym)|uniprotkb:KIAA0516(gene name synonym)|uniprotkb:MAPK8IP4(gene name synonym)|uniprotkb:SYD1(gene name synonym) psi-mi:"MI:0030"(cross-linking study) Tang et al. (2019) imex:IM-28478|pubmed:31412244 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-26443127|imex:IM-28478-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:XP_011543165.1|ensembl:ENSP00000366475|ensembl:ENST00000421419|ensembl:ENSP00000410522|refseq:NP_055919.2|ensembl:ENSG00000110046(gene)|ensembl:ENST00000377264(transcript)|go:"GO:0000045"(autophagosome assembly)|go:"GO:0000407"(phagophore assembly site)|go:"GO:0000422"(autophagy of mitochondrion)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005811"(lipid droplet)|go:"GO:0019898"(extrinsic component of membrane)|go:"GO:0032266"(phosphatidylinositol-3-phosphate binding)|go:"GO:0034045"(phagophore assembly site membrane)|go:"GO:0034727"(piecemeal microautophagy of the nucleus)|go:"GO:0044805"(late nucleophagy)|interpro:IPR015412(ATG2, C-terminal)|interpro:IPR026849|interpro:IPR026854|rcsb pdb:6KLR|go:"GO:0061709"(reticulophagy) refseq:NP_001123999.1|refseq:NP_001238900.1|refseq:NP_001124000.1|refseq:NP_003962.3|ensembl:ENSG00000008294(gene)|ensembl:ENST00000262013(transcript)|go:"GO:0001669"(acrosomal vesicle)|go:"GO:0001933"(negative regulation of protein phosphorylation)|go:"GO:0005078"(MAP-kinase scaffold activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005829"(cytosol)|go:"GO:0007257"(obsolete activation of JUN kinase activity)|go:"GO:0008432"(JUN kinase binding)|go:"GO:0016192"(vesicle-mediated transport)|go:"GO:0019894"(kinesin binding)|go:"GO:0030159"(signaling receptor complex adaptor activity)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0032418"(lysosome localization)|go:"GO:0034451"(centriolar satellite)|go:"GO:0042147"(retrograde transport, endosome to Golgi)|go:"GO:0042802"(identical protein binding)|go:"GO:0045665"(negative regulation of neuron differentiation)|go:"GO:0045666"(positive regulation of neuron differentiation)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051146"(striated muscle cell differentiation)|go:"GO:0070062"(extracellular exosome)|go:"GO:1903860"(negative regulation of dendrite extension)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019143|interpro:IPR032486|interpro:IPR034743|interpro:IPR034744|interpro:IPR036322|interpro:IPR039911|mint:O60271|rcsb pdb:2W83|reactome:R-HSA-525793 - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/10/21 2020/11/06 rogid:RC80jQqKw4ekVFudqz/IunWCEMA9606 rogid:UsItS/q6arsUKVnp+hGuBZE3P809606 rigid:319IsGV1oRp3OLZk5khzgtmEExU false enhanced green fluorescent protein tag:n-n|sufficient binding region:1776-1820 - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q2TAZ0 uniprotkb:Q9NRY5 intact:EBI-2514077|intact:EBI-28978291|uniprotkb:Q8TAI8|uniprotkb:O43154|uniprotkb:Q14DM2|uniprotkb:Q7Z6K8|uniprotkb:Q6ZTV2|uniprotkb:Q96HH7|uniprotkb:Q8IVY5|ensembl:ENSP00000366475 intact:EBI-10973142|ensembl:ENSP00000430384|ensembl:ENSP00000430489|ensembl:ENSP00000341597|uniprotkb:Q9H7E0|uniprotkb:B2R8D8 psi-mi:atg2a_human(display_long)|uniprotkb:ATG2A(gene name)|psi-mi:ATG2A(display_short)|uniprotkb:KIAA0404(gene name synonym) psi-mi:f1142_human(display_long)|uniprotkb:FAM114A2(gene name)|psi-mi:FAM114A2(display_short)|uniprotkb:C5orf3(gene name synonym) psi-mi:"MI:0030"(cross-linking study) Tang et al. (2019) imex:IM-28478|pubmed:31412244 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-26443127|imex:IM-28478-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:XP_011543165.1|ensembl:ENSP00000366475|ensembl:ENST00000421419|ensembl:ENSP00000410522|refseq:NP_055919.2|ensembl:ENSG00000110046(gene)|ensembl:ENST00000377264(transcript)|go:"GO:0000045"(autophagosome assembly)|go:"GO:0000407"(phagophore assembly site)|go:"GO:0000422"(autophagy of mitochondrion)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005811"(lipid droplet)|go:"GO:0019898"(extrinsic component of membrane)|go:"GO:0032266"(phosphatidylinositol-3-phosphate binding)|go:"GO:0034045"(phagophore assembly site membrane)|go:"GO:0034727"(piecemeal microautophagy of the nucleus)|go:"GO:0044805"(late nucleophagy)|interpro:IPR015412(ATG2, C-terminal)|interpro:IPR026849|interpro:IPR026854|rcsb pdb:6KLR|go:"GO:0061709"(reticulophagy) refseq:NP_001304922.1|refseq:NP_001304923.1|refseq:NP_001304924.1|refseq:NP_061161.2|refseq:XP_005268417.1|refseq:XP_005268418.1|refseq:XP_011535842.1|refseq:XP_011535843.1|refseq:XP_011535844.1|ensembl:ENST00000351797(transcript)|ensembl:ENST00000520667(transcript)|ensembl:ENST00000522858(transcript)|go:"GO:0017076"(purine nucleotide binding)|interpro:IPR007998(Protein of unknown function DUF719)|mint:Q9NRY5|reactome:R-HSA-6802952|ensembl:ENSG00000055147(gene)|refseq:XP_016864456.1|refseq:XP_016864457.1 - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/10/21 2020/11/06 rogid:RC80jQqKw4ekVFudqz/IunWCEMA9606 rogid:HHA13BmHMbBiHCHhfOIKh3511nM9606 rigid:319IsGV1oRp3OLZk5khzgtmEExU false enhanced green fluorescent protein tag:n-n|sufficient binding region:1776-1820 - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q2TAZ0 uniprotkb:P07099 intact:EBI-2514077|intact:EBI-28978291|uniprotkb:Q8TAI8|uniprotkb:O43154|uniprotkb:Q14DM2|uniprotkb:Q7Z6K8|uniprotkb:Q6ZTV2|uniprotkb:Q96HH7|uniprotkb:Q8IVY5|ensembl:ENSP00000366475 intact:EBI-6138796|uniprotkb:B2R8N0|uniprotkb:Q5VTJ6|uniprotkb:Q9NP75|uniprotkb:Q9NPE7|uniprotkb:Q9NQU6|uniprotkb:Q9NQU7|uniprotkb:Q9NQU8|uniprotkb:Q9NQU9|uniprotkb:Q9NQV0|uniprotkb:Q9NQV1|uniprotkb:Q9NQV2|ensembl:ENSP00000272167|ensembl:ENSP00000355802|ensembl:ENSP00000480004 psi-mi:atg2a_human(display_long)|uniprotkb:ATG2A(gene name)|psi-mi:ATG2A(display_short)|uniprotkb:KIAA0404(gene name synonym) psi-mi:hyep_human(display_long)|uniprotkb:EPHX1(gene name)|psi-mi:EPHX1(display_short)|uniprotkb:EPHX(gene name synonym)|uniprotkb:EPOX(gene name synonym)|uniprotkb:Epoxide hydratase(gene name synonym)|uniprotkb:Microsomal epoxide hydrolase(gene name synonym) psi-mi:"MI:0030"(cross-linking study) Tang et al. (2019) imex:IM-28478|pubmed:31412244 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-26443127|imex:IM-28478-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:XP_011543165.1|ensembl:ENSP00000366475|ensembl:ENST00000421419|ensembl:ENSP00000410522|refseq:NP_055919.2|ensembl:ENSG00000110046(gene)|ensembl:ENST00000377264(transcript)|go:"GO:0000045"(autophagosome assembly)|go:"GO:0000407"(phagophore assembly site)|go:"GO:0000422"(autophagy of mitochondrion)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005811"(lipid droplet)|go:"GO:0019898"(extrinsic component of membrane)|go:"GO:0032266"(phosphatidylinositol-3-phosphate binding)|go:"GO:0034045"(phagophore assembly site membrane)|go:"GO:0034727"(piecemeal microautophagy of the nucleus)|go:"GO:0044805"(late nucleophagy)|interpro:IPR015412(ATG2, C-terminal)|interpro:IPR026849|interpro:IPR026854|rcsb pdb:6KLR|go:"GO:0061709"(reticulophagy) refseq:NP_001278092.1|refseq:NP_000111.1|refseq:NP_001129490.1|ensembl:ENSG00000143819(gene)|ensembl:ENST00000272167(transcript)|ensembl:ENST00000366837(transcript)|ensembl:ENST00000614058(transcript)|go:"GO:0004301"(epoxide hydrolase activity)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006805"(xenobiotic metabolic process)|go:"GO:0009636"(response to toxic substance)|go:"GO:0014070"(response to organic cyclic compound)|go:"GO:0016021"(integral component of membrane)|go:"GO:0019369"(arachidonic acid metabolic process)|go:"GO:0019439"(aromatic compound catabolic process)|go:"GO:0033961"(cis-stilbene-oxide hydrolase activity)|go:"GO:0097176"(epoxide metabolic process)|interpro:IPR000073(Alpha/beta hydrolase fold-1)|interpro:IPR000639(Epoxide hydrolase-like)|interpro:IPR016292(Epoxide hydrolase)|interpro:IPR029058|reactome:R-HSA-211945 - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/10/21 2020/11/06 rogid:RC80jQqKw4ekVFudqz/IunWCEMA9606 rogid:VtIgDuQpQQbLSdFLOBBx9yHHiBE9606 rigid:319IsGV1oRp3OLZk5khzgtmEExU false enhanced green fluorescent protein tag:n-n|sufficient binding region:1776-1820 - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q2TAZ0 uniprotkb:O95249 intact:EBI-2514077|intact:EBI-28978291|uniprotkb:Q8TAI8|uniprotkb:O43154|uniprotkb:Q14DM2|uniprotkb:Q7Z6K8|uniprotkb:Q6ZTV2|uniprotkb:Q96HH7|uniprotkb:Q8IVY5|ensembl:ENSP00000366475 intact:EBI-3235244|ensembl:ENSP00000225724|uniprotkb:O75392|uniprotkb:J3KST5 psi-mi:atg2a_human(display_long)|uniprotkb:ATG2A(gene name)|psi-mi:ATG2A(display_short)|uniprotkb:KIAA0404(gene name synonym) psi-mi:gosr1_human(display_long)|uniprotkb:GOSR1(gene name)|psi-mi:GOSR1(display_short)|uniprotkb:GS28(gene name synonym)|uniprotkb:28 kDa Golgi SNARE protein(gene name synonym)|uniprotkb:28 kDa cis-Golgi SNARE p28(gene name synonym) psi-mi:"MI:0030"(cross-linking study) Tang et al. (2019) imex:IM-28478|pubmed:31412244 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-26443127|imex:IM-28478-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:XP_011543165.1|ensembl:ENSP00000366475|ensembl:ENST00000421419|ensembl:ENSP00000410522|refseq:NP_055919.2|ensembl:ENSG00000110046(gene)|ensembl:ENST00000377264(transcript)|go:"GO:0000045"(autophagosome assembly)|go:"GO:0000407"(phagophore assembly site)|go:"GO:0000422"(autophagy of mitochondrion)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005811"(lipid droplet)|go:"GO:0019898"(extrinsic component of membrane)|go:"GO:0032266"(phosphatidylinositol-3-phosphate binding)|go:"GO:0034045"(phagophore assembly site membrane)|go:"GO:0034727"(piecemeal microautophagy of the nucleus)|go:"GO:0044805"(late nucleophagy)|interpro:IPR015412(ATG2, C-terminal)|interpro:IPR026849|interpro:IPR026854|rcsb pdb:6KLR|go:"GO:0061709"(reticulophagy) ensembl:ENSG00000108587(gene)|ensembl:ENST00000225724(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0005484"(SNAP receptor activity)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005797"(Golgi medial cisterna)|go:"GO:0005801"(cis-Golgi network)|go:"GO:0005829"(cytosol)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0006891"(intra-Golgi vesicle-mediated transport)|go:"GO:0006906"(vesicle fusion)|go:"GO:0015031"(protein transport)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030133"(transport vesicle)|go:"GO:0031201"(SNARE complex)|go:"GO:0042147"(retrograde transport, endosome to Golgi)|go:"GO:0048209"(regulation of vesicle targeting, to, from or within Golgi)|interpro:IPR023601|mint:O95249|reactome:R-HSA-6807878|reactome:R-HSA-6811438|refseq:NP_001007025.1|refseq:NP_001007026.1|refseq:NP_004862.1|refseq:XP_005258129.1 - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/10/21 2020/11/06 rogid:RC80jQqKw4ekVFudqz/IunWCEMA9606 rogid:zebOuVPnYg5z3XqCa5rMI2IR/jY9606 rigid:319IsGV1oRp3OLZk5khzgtmEExU false enhanced green fluorescent protein tag:n-n|sufficient binding region:1776-1820 - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q2TAZ0 uniprotkb:Q14318 intact:EBI-2514077|intact:EBI-28978291|uniprotkb:Q8TAI8|uniprotkb:O43154|uniprotkb:Q14DM2|uniprotkb:Q7Z6K8|uniprotkb:Q6ZTV2|uniprotkb:Q96HH7|uniprotkb:Q8IVY5|ensembl:ENSP00000366475 intact:EBI-724839|uniprotkb:Q53GU3|uniprotkb:Q7Z349|uniprotkb:Q86YK6|ensembl:ENSP00000222308|ensembl:ENSP00000472302|uniprotkb:C8C9T5 psi-mi:atg2a_human(display_long)|uniprotkb:ATG2A(gene name)|psi-mi:ATG2A(display_short)|uniprotkb:KIAA0404(gene name synonym) psi-mi:fkbp8_human(display_long)|uniprotkb:FK506-binding protein 8(gene name synonym)|uniprotkb:38 kDa FK506-binding protein(gene name synonym)|uniprotkb:FKBPR38(gene name synonym)|uniprotkb:FKBP8(gene name)|psi-mi:FKBP8(display_short)|uniprotkb:FKBP38(gene name synonym)|uniprotkb:Rotamase(gene name synonym) psi-mi:"MI:0030"(cross-linking study) Tang et al. (2019) imex:IM-28478|pubmed:31412244 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-26443127|imex:IM-28478-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:XP_011543165.1|ensembl:ENSP00000366475|ensembl:ENST00000421419|ensembl:ENSP00000410522|refseq:NP_055919.2|ensembl:ENSG00000110046(gene)|ensembl:ENST00000377264(transcript)|go:"GO:0000045"(autophagosome assembly)|go:"GO:0000407"(phagophore assembly site)|go:"GO:0000422"(autophagy of mitochondrion)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005811"(lipid droplet)|go:"GO:0019898"(extrinsic component of membrane)|go:"GO:0032266"(phosphatidylinositol-3-phosphate binding)|go:"GO:0034045"(phagophore assembly site membrane)|go:"GO:0034727"(piecemeal microautophagy of the nucleus)|go:"GO:0044805"(late nucleophagy)|interpro:IPR015412(ATG2, C-terminal)|interpro:IPR026849|interpro:IPR026854|rcsb pdb:6KLR|go:"GO:0061709"(reticulophagy) refseq:NP_036313.3|refseq:NP_001295302.1|go:"GO:0001708"(cell fate specification)|go:"GO:0001933"(negative regulation of protein phosphorylation)|go:"GO:0003755"(peptidyl-prolyl cis-trans isomerase activity)|go:"GO:0005739"(mitochondrion)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005829"(cytosol)|go:"GO:0006457"(protein folding)|go:"GO:0006915"(apoptotic process)|go:"GO:0007224"(smoothened signaling pathway)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0016020"(membrane)|go:"GO:0021904"(dorsal/ventral neural tube patterning)|go:"GO:0030176"(integral component of endoplasmic reticulum membrane)|go:"GO:0030513"(positive regulation of BMP signaling pathway)|go:"GO:0031966"(mitochondrial membrane)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035264"(multicellular organism growth)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0042802"(identical protein binding)|go:"GO:0043010"(camera-type eye development)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0044183"(protein folding chaperone)|go:"GO:0046872"(metal ion binding)|go:"GO:0097718"(disordered domain specific binding)|interpro:IPR001179(Peptidyl-prolyl cis-trans isomerase, FKBP-type)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR013105(Tetratricopeptide TPR2)|interpro:IPR019734|mint:Q14318|ensembl:ENSG00000105701(gene)|rcsb pdb:2AWG|rcsb pdb:2D9F|rcsb pdb:2F2D|rcsb pdb:2MF9|rcsb pdb:3EY6|rcsb pdb:5MGX|reactome:R-HSA-5689880|ensembl:ENST00000222308(transcript)|ensembl:ENST00000596558(transcript)|refseq:XP_011526165.1|dip:DIP-42200N - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/10/21 2020/11/06 rogid:RC80jQqKw4ekVFudqz/IunWCEMA9606 rogid:CpZqwry5szPluwNMwWXshCIMUvY9606 rigid:319IsGV1oRp3OLZk5khzgtmEExU false enhanced green fluorescent protein tag:n-n|sufficient binding region:1776-1820 - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q2TAZ0 uniprotkb:P98194 intact:EBI-2514077|intact:EBI-28978291|uniprotkb:Q8TAI8|uniprotkb:O43154|uniprotkb:Q14DM2|uniprotkb:Q7Z6K8|uniprotkb:Q6ZTV2|uniprotkb:Q96HH7|uniprotkb:Q8IVY5|ensembl:ENSP00000366475 intact:EBI-2939877|ensembl:ENSP00000395809|ensembl:ENSP00000424783|ensembl:ENSP00000427461|uniprotkb:B2RAT7|uniprotkb:O76005|uniprotkb:Q86V72|uniprotkb:Q86V73|uniprotkb:Q8N6V1|uniprotkb:Q8NCJ7|uniprotkb:B4DSW3|uniprotkb:B7Z3X9|uniprotkb:G3XAH8|uniprotkb:G8JLN9 psi-mi:atg2a_human(display_long)|uniprotkb:ATG2A(gene name)|psi-mi:ATG2A(display_short)|uniprotkb:KIAA0404(gene name synonym) psi-mi:at2c1_human(display_long)|uniprotkb:ATP2C1(gene name)|psi-mi:ATP2C1(display_short)|uniprotkb:KIAA1347(gene name synonym)|uniprotkb:PMR1L(gene name synonym)|uniprotkb:"ATP-dependent Ca(2+) pump PMR1"(gene name synonym)|uniprotkb:"Ca(2+)/Mn(2+)-ATPase 2C1"(gene name synonym)|uniprotkb:"Secretory pathway Ca(2+)-transporting ATPase type 1"(gene name synonym)|uniprotkb:HUSSY-28(orf name) psi-mi:"MI:0030"(cross-linking study) Tang et al. (2019) imex:IM-28478|pubmed:31412244 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-26443127|imex:IM-28478-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:XP_011543165.1|ensembl:ENSP00000366475|ensembl:ENST00000421419|ensembl:ENSP00000410522|refseq:NP_055919.2|ensembl:ENSG00000110046(gene)|ensembl:ENST00000377264(transcript)|go:"GO:0000045"(autophagosome assembly)|go:"GO:0000407"(phagophore assembly site)|go:"GO:0000422"(autophagy of mitochondrion)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005811"(lipid droplet)|go:"GO:0019898"(extrinsic component of membrane)|go:"GO:0032266"(phosphatidylinositol-3-phosphate binding)|go:"GO:0034045"(phagophore assembly site membrane)|go:"GO:0034727"(piecemeal microautophagy of the nucleus)|go:"GO:0044805"(late nucleophagy)|interpro:IPR015412(ATG2, C-terminal)|interpro:IPR026849|interpro:IPR026854|rcsb pdb:6KLR|go:"GO:0061709"(reticulophagy) ensembl:ENSG00000017260(gene)|ensembl:ENST00000428331(transcript)|ensembl:ENST00000508532(transcript)|ensembl:ENST00000510168(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0005388"(P-type calcium transporter activity)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0005886"(plasma membrane)|go:"GO:0006816"(calcium ion transport)|go:"GO:0006828"(manganese ion transport)|go:"GO:0006874"(cellular calcium ion homeostasis)|go:"GO:0030026"(cellular manganese ion homeostasis)|go:"GO:0008544"(epidermis development)|go:"GO:0008553"(P-type proton-exporting transporter activity)|go:"GO:0030145"(manganese ion binding)|go:"GO:0015410"(ABC-type manganese transporter activity)|go:"GO:0030173"(integral component of Golgi membrane)|go:"GO:0031532"(actin cytoskeleton reorganization)|go:"GO:0032468"(Golgi calcium ion homeostasis)|go:"GO:0032472"(Golgi calcium ion transport)|go:"GO:0032580"(Golgi cisterna membrane)|go:"GO:0033106"(cis-Golgi network membrane)|go:"GO:0042998"(positive regulation of Golgi to plasma membrane protein transport)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0046872"(metal ion binding)|go:"GO:0070588"(calcium ion transmembrane transport)|go:"GO:0098629"(trans-Golgi network membrane organization)|go:"GO:0140613"(P-type manganese transporter activity)|interpro:IPR001757(ATPase, P-type, K/Mg/Cd/Cu/Zn/Na/Ca/Na/H-transporter)|interpro:IPR004014(ATPase, P-type cation-transporter, N-terminal)|interpro:IPR006068(ATPase, P-type cation-transporter, C-terminal)|interpro:IPR006413(Calcium-transporting P-type ATPase, PMR1-type)|interpro:IPR008250(E1-E2 ATPase-associated region)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016339"(calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules)|interpro:IPR018303|interpro:IPR023214|interpro:IPR023298|interpro:IPR023299|interpro:IPR030336|interpro:IPR036412|interpro:IPR044492|reactome:R-HSA-936837|refseq:NP_001001485.1|refseq:NP_001001486.1|refseq:NP_001001487.1|refseq:NP_001186108.1|refseq:NP_001186109.1|refseq:NP_001186110.1|refseq:NP_001186111.1|refseq:NP_001186112.1|refseq:NP_001186113.1|refseq:NP_001186114.1|refseq:NP_055197.2|refseq:XP_016861653.1|refseq:XP_005247412.1|refseq:XP_005247413.1 - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/10/21 2020/11/06 rogid:RC80jQqKw4ekVFudqz/IunWCEMA9606 rogid:jPAb8dnATDdbBvc++3El2w2Zaeg9606 rigid:319IsGV1oRp3OLZk5khzgtmEExU false enhanced green fluorescent protein tag:n-n|sufficient binding region:1776-1820 - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q2TAZ0 uniprotkb:Q8N6T3 intact:EBI-2514077|intact:EBI-28978291|uniprotkb:Q8TAI8|uniprotkb:O43154|uniprotkb:Q14DM2|uniprotkb:Q7Z6K8|uniprotkb:Q6ZTV2|uniprotkb:Q96HH7|uniprotkb:Q8IVY5|ensembl:ENSP00000366475 intact:EBI-716933|uniprotkb:Q6PK71|uniprotkb:Q96KC4|uniprotkb:Q96T02|uniprotkb:Q9NSU3|uniprotkb:Q9NVF6|uniprotkb:Q9UIL0|uniprotkb:B7ZBI3|uniprotkb:E1P5I9|ensembl:ENSP00000359306|uniprotkb:B7Z3U0|uniprotkb:E7EV62|uniprotkb:B7Z8H8 psi-mi:atg2a_human(display_long)|uniprotkb:ATG2A(gene name)|psi-mi:ATG2A(display_short)|uniprotkb:KIAA0404(gene name synonym) psi-mi:arfg1_human(display_long)|uniprotkb:ADP-ribosylation factor 1 GTPase-activating protein(gene name synonym)|uniprotkb:ARF1-directed GTPase-activating protein(gene name synonym)|uniprotkb:ARFGAP1(gene name)|psi-mi:ARFGAP1(display_short)|uniprotkb:ARF1GAP(gene name synonym) psi-mi:"MI:0030"(cross-linking study) Tang et al. (2019) imex:IM-28478|pubmed:31412244 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-26443127|imex:IM-28478-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:XP_011543165.1|ensembl:ENSP00000366475|ensembl:ENST00000421419|ensembl:ENSP00000410522|refseq:NP_055919.2|ensembl:ENSG00000110046(gene)|ensembl:ENST00000377264(transcript)|go:"GO:0000045"(autophagosome assembly)|go:"GO:0000407"(phagophore assembly site)|go:"GO:0000422"(autophagy of mitochondrion)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005811"(lipid droplet)|go:"GO:0019898"(extrinsic component of membrane)|go:"GO:0032266"(phosphatidylinositol-3-phosphate binding)|go:"GO:0034045"(phagophore assembly site membrane)|go:"GO:0034727"(piecemeal microautophagy of the nucleus)|go:"GO:0044805"(late nucleophagy)|interpro:IPR015412(ATG2, C-terminal)|interpro:IPR026849|interpro:IPR026854|rcsb pdb:6KLR|go:"GO:0061709"(reticulophagy) refseq:NP_060679.1|refseq:NP_783202.1|refseq:NP_001268411.1|refseq:NP_001268412.1|refseq:NP_001268413.1|ensembl:ENSG00000101199(gene)|ensembl:ENST00000370283(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005829"(cytosol)|go:"GO:0015031"(protein transport)|go:"GO:0016192"(vesicle-mediated transport)|go:"GO:0030100"(regulation of endocytosis)|go:"GO:0032012"(regulation of ARF protein signal transduction)|go:"GO:0045202"(synapse)|go:"GO:0046872"(metal ion binding)|interpro:IPR001164(Arf GTPase activating protein)|interpro:IPR037278|interpro:IPR038508|mint:Q8N6T3|rcsb pdb:3DWD|rcsb pdb:3O47|reactome:R-HSA-381038|reactome:R-HSA-6807878|reactome:R-HSA-6811434|reactome:R-HSA-8856828 - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/10/21 2020/11/06 rogid:RC80jQqKw4ekVFudqz/IunWCEMA9606 rogid:vAIMUqWHtBQzZYe5JJp6WEMXQdo9606 rigid:319IsGV1oRp3OLZk5khzgtmEExU false enhanced green fluorescent protein tag:n-n|sufficient binding region:1776-1820 - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q2TAZ0 uniprotkb:O00429 intact:EBI-2514077|intact:EBI-28978291|uniprotkb:Q8TAI8|uniprotkb:O43154|uniprotkb:Q14DM2|uniprotkb:Q7Z6K8|uniprotkb:Q6ZTV2|uniprotkb:Q96HH7|uniprotkb:Q8IVY5|ensembl:ENSP00000366475 intact:EBI-724571|uniprotkb:O14541|uniprotkb:O60709|uniprotkb:Q7L6B3|uniprotkb:Q8TBT7|uniprotkb:Q9BWM1|uniprotkb:Q9Y5J2|uniprotkb:B4DSU8|uniprotkb:A8K4X9|ensembl:ENSP00000450399|uniprotkb:B4DGC9|uniprotkb:J3KPI2|uniprotkb:Q59GN9|uniprotkb:G8JLD5 psi-mi:atg2a_human(display_long)|uniprotkb:ATG2A(gene name)|psi-mi:ATG2A(display_short)|uniprotkb:KIAA0404(gene name synonym) psi-mi:dnm1l_human(display_long)|uniprotkb:Dynamin-like protein(gene name synonym)|uniprotkb:Dnm1p/Vps1p-like protein(gene name synonym)|uniprotkb:Dynamin family member proline-rich carboxyl-terminal domain less(gene name synonym)|uniprotkb:Dynamin-related protein 1(gene name synonym)|uniprotkb:Dynamin-like protein 4(gene name synonym)|uniprotkb:Dynamin-like protein IV(gene name synonym)|uniprotkb:DNM1L(gene name)|psi-mi:DNM1L(display_short)|uniprotkb:DLP1(gene name synonym)|uniprotkb:DRP1(gene name synonym) psi-mi:"MI:0030"(cross-linking study) Tang et al. (2019) imex:IM-28478|pubmed:31412244 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-26443127|imex:IM-28478-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:XP_011543165.1|ensembl:ENSP00000366475|ensembl:ENST00000421419|ensembl:ENSP00000410522|refseq:NP_055919.2|ensembl:ENSG00000110046(gene)|ensembl:ENST00000377264(transcript)|go:"GO:0000045"(autophagosome assembly)|go:"GO:0000407"(phagophore assembly site)|go:"GO:0000422"(autophagy of mitochondrion)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005811"(lipid droplet)|go:"GO:0019898"(extrinsic component of membrane)|go:"GO:0032266"(phosphatidylinositol-3-phosphate binding)|go:"GO:0034045"(phagophore assembly site membrane)|go:"GO:0034727"(piecemeal microautophagy of the nucleus)|go:"GO:0044805"(late nucleophagy)|interpro:IPR015412(ATG2, C-terminal)|interpro:IPR026849|interpro:IPR026854|rcsb pdb:6KLR|go:"GO:0061709"(reticulophagy) refseq:NP_005681.2|refseq:NP_036192.2|refseq:NP_036193.2|ensembl:ENSG00000087470(gene)|ensembl:ENST00000549701(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0000266"(mitochondrial fission)|go:"GO:0001836"(release of cytochrome c from mitochondria)|go:"GO:0003374"(dynamin family protein polymerization involved in mitochondrial fission)|go:"GO:0003924"(GTPase activity)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005777"(peroxisome)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0005874"(microtubule)|go:"GO:0005903"(brush border)|go:"GO:0005905"(clathrin-coated pit)|go:"GO:0006816"(calcium ion transport)|go:"GO:0007005"(mitochondrion organization)|go:"GO:0008017"(microtubule binding)|go:"GO:0008289"(lipid binding)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0010637"(negative regulation of mitochondrial fusion)|go:"GO:0010821"(regulation of mitochondrion organization)|go:"GO:0016020"(membrane)|go:"GO:0016559"(peroxisome fission)|go:"GO:0030276"(clathrin binding)|go:"GO:0030672"(synaptic vesicle membrane)|go:"GO:0030742"(GTP-dependent protein binding)|go:"GO:0031267"(small GTPase binding)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0031966"(mitochondrial membrane)|go:"GO:0032991"(protein-containing complex)|go:"GO:0036466"(synaptic vesicle recycling via endosome)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0043653"(mitochondrial fragmentation involved in apoptotic process)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0048312"(intracellular distribution of mitochondria)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0048488"(synaptic vesicle endocytosis)|go:"GO:0048511"(rhythmic process)|go:"GO:0050714"(positive regulation of protein secretion)|go:"GO:0051259"(protein complex oligomerization)|go:"GO:0051433"(BH2 domain binding)|go:"GO:0060047"(heart contraction)|go:"GO:0061003"(positive regulation of dendritic spine morphogenesis)|go:"GO:0061025"(membrane fusion)|go:"GO:0065003"(protein-containing complex assembly)|go:"GO:0070266"(necroptotic process)|go:"GO:0070584"(mitochondrion morphogenesis)|go:"GO:0070585"(protein localization to mitochondrion)|go:"GO:0090023"(positive regulation of neutrophil chemotaxis)|go:"GO:0090141"(positive regulation of mitochondrial fission)|go:"GO:0090149"(mitochondrial membrane fission)|go:"GO:0090200"(positive regulation of release of cytochrome c from mitochondria)|go:"GO:0090650"(cellular response to oxygen-glucose deprivation)|go:"GO:1900244"(positive regulation of synaptic vesicle endocytosis)|go:"GO:1903146"(regulation of autophagy of mitochondrion)|go:"GO:1903578"(regulation of ATP metabolic process)|go:"GO:1904579"(cellular response to thapsigargin)|go:"GO:1904666"(regulation of ubiquitin protein ligase activity)|go:"GO:1905395"(response to flavonoid)|go:"GO:1990910"(response to hypobaric hypoxia)|go:"GO:2000302"(positive regulation of synaptic vesicle exocytosis)|go:"GO:2001244"(positive regulation of intrinsic apoptotic signaling pathway)|interpro:IPR000375(Dynamin central region)|interpro:IPR001401(Dynamin, GTPase region)|interpro:IPR003130(Dynamin GTPase effector)|interpro:IPR019762|interpro:IPR020850|interpro:IPR022812|interpro:IPR027417|interpro:IPR030381|interpro:IPR030556|mint:O00429|rcsb pdb:3W6N|rcsb pdb:3W6O|rcsb pdb:3W6P|rcsb pdb:4BEJ|rcsb pdb:4H1U|rcsb pdb:4H1V|rcsb pdb:5WP9|go:"GO:0098835"(presynaptic endocytic zone membrane)|go:"GO:1900063"(regulation of peroxisome organization)|reactome:R-HSA-75153|refseq:NP_001265392.1|refseq:NP_001265393.1|refseq:NP_001265394.1|refseq:NP_001265395.1|refseq:NP_001317309.1|dip:DIP-42704N - - crc64:F9521A376B785B71 figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/10/21 2020/11/06 rogid:RC80jQqKw4ekVFudqz/IunWCEMA9606 rogid:hmh7m80FPMdx6/3eUY6l0IK/AqY9606 rigid:319IsGV1oRp3OLZk5khzgtmEExU false enhanced green fluorescent protein tag:n-n|sufficient binding region:1776-1820 - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q2TAZ0 uniprotkb:Q96S66 intact:EBI-2514077|intact:EBI-28978291|uniprotkb:Q8TAI8|uniprotkb:O43154|uniprotkb:Q14DM2|uniprotkb:Q7Z6K8|uniprotkb:Q6ZTV2|uniprotkb:Q96HH7|uniprotkb:Q8IVY5|ensembl:ENSP00000366475 intact:EBI-2836109|uniprotkb:Q8WYP9|uniprotkb:Q8WYP8|uniprotkb:O94861|uniprotkb:Q9BU25|ensembl:ENSP00000349456|ensembl:ENSP00000358986|ensembl:ENSP00000502251|ensembl:ENSP00000502457|ensembl:ENSP00000502648|ensembl:ENSP00000502836 psi-mi:atg2a_human(display_long)|uniprotkb:ATG2A(gene name)|psi-mi:ATG2A(display_short)|uniprotkb:KIAA0404(gene name synonym) psi-mi:clcc1_human(display_long)|uniprotkb:CLCC1(gene name)|psi-mi:CLCC1(display_short)|uniprotkb:KIAA0761(gene name synonym)|uniprotkb:MCLC(gene name synonym)|uniprotkb:Mid-1-related chloride channel protein 1(gene name synonym) psi-mi:"MI:0030"(cross-linking study) Tang et al. (2019) imex:IM-28478|pubmed:31412244 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-26443127|imex:IM-28478-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:XP_011543165.1|ensembl:ENSP00000366475|ensembl:ENST00000421419|ensembl:ENSP00000410522|refseq:NP_055919.2|ensembl:ENSG00000110046(gene)|ensembl:ENST00000377264(transcript)|go:"GO:0000045"(autophagosome assembly)|go:"GO:0000407"(phagophore assembly site)|go:"GO:0000422"(autophagy of mitochondrion)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005811"(lipid droplet)|go:"GO:0019898"(extrinsic component of membrane)|go:"GO:0032266"(phosphatidylinositol-3-phosphate binding)|go:"GO:0034045"(phagophore assembly site membrane)|go:"GO:0034727"(piecemeal microautophagy of the nucleus)|go:"GO:0044805"(late nucleophagy)|interpro:IPR015412(ATG2, C-terminal)|interpro:IPR026849|interpro:IPR026854|rcsb pdb:6KLR|go:"GO:0061709"(reticulophagy) refseq:NP_001041675.1|refseq:NP_055942.1|refseq:NP_001265131.1|refseq:NP_001265132.1|ensembl:ENSG00000121940(gene)|ensembl:ENST00000356970(transcript)|ensembl:ENST00000369969(transcript)|ensembl:ENST00000674849(transcript)|ensembl:ENST00000675508(transcript)|ensembl:ENST00000675654(transcript)|ensembl:ENST00000675956(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0005254"(chloride channel activity)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006821"(chloride transport)|go:"GO:0016020"(membrane)|go:"GO:0031965"(nuclear membrane)|go:"GO:0034707"(chloride channel complex)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0044233"(mitochondria-associated endoplasmic reticulum membrane)|interpro:IPR009231(Mid-1-related chloride channel) - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/10/21 2020/11/06 rogid:RC80jQqKw4ekVFudqz/IunWCEMA9606 rogid:l1dx06MXJa4s4kcVIvr1rRm9Wu09606 rigid:319IsGV1oRp3OLZk5khzgtmEExU false enhanced green fluorescent protein tag:n-n|sufficient binding region:1776-1820 - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q2TAZ0 uniprotkb:Q16891 intact:EBI-2514077|intact:EBI-28978291|uniprotkb:Q8TAI8|uniprotkb:O43154|uniprotkb:Q14DM2|uniprotkb:Q7Z6K8|uniprotkb:Q6ZTV2|uniprotkb:Q96HH7|uniprotkb:Q8IVY5|ensembl:ENSP00000366475 intact:EBI-473801|uniprotkb:Q68D41|uniprotkb:B2R5N6|uniprotkb:Q14539|uniprotkb:Q15092|uniprotkb:Q69HW5|uniprotkb:Q6IBL0|uniprotkb:Q7Z3X1|uniprotkb:Q8TAJ5|uniprotkb:Q9P0V2|uniprotkb:B1H0U5|ensembl:ENSP00000387262 psi-mi:atg2a_human(display_long)|uniprotkb:ATG2A(gene name)|psi-mi:ATG2A(display_short)|uniprotkb:KIAA0404(gene name synonym) psi-mi:mic60_human(display_long)|uniprotkb:Mitofilin(gene name synonym)|uniprotkb:p87/89(gene name synonym)|uniprotkb:Cell proliferation-inducing gene 4/52 protein(gene name synonym)|uniprotkb:MIC60(gene name synonym)|uniprotkb:IMMT(gene name)|psi-mi:IMMT(display_short)|uniprotkb:HMP(gene name synonym)|uniprotkb:MINOS2(gene name synonym)|uniprotkb:Mitochondrial inner membrane protein(gene name synonym)|uniprotkb:PIG4(orf name)|uniprotkb:PIG52(orf name) psi-mi:"MI:0030"(cross-linking study) Tang et al. (2019) imex:IM-28478|pubmed:31412244 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-26443127|imex:IM-28478-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:XP_011543165.1|ensembl:ENSP00000366475|ensembl:ENST00000421419|ensembl:ENSP00000410522|refseq:NP_055919.2|ensembl:ENSG00000110046(gene)|ensembl:ENST00000377264(transcript)|go:"GO:0000045"(autophagosome assembly)|go:"GO:0000407"(phagophore assembly site)|go:"GO:0000422"(autophagy of mitochondrion)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005811"(lipid droplet)|go:"GO:0019898"(extrinsic component of membrane)|go:"GO:0032266"(phosphatidylinositol-3-phosphate binding)|go:"GO:0034045"(phagophore assembly site membrane)|go:"GO:0034727"(piecemeal microautophagy of the nucleus)|go:"GO:0044805"(late nucleophagy)|interpro:IPR015412(ATG2, C-terminal)|interpro:IPR026849|interpro:IPR026854|rcsb pdb:6KLR|go:"GO:0061709"(reticulophagy) refseq:NP_001093639.1|refseq:NP_001093640.1|refseq:NP_006830.2|refseq:XP_005264170.1|ensembl:ENSG00000132305(gene)|ensembl:ENST00000410111(transcript)|go:"GO:0001401"(SAM complex)|go:"GO:0003723"(RNA binding)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005758"(mitochondrial intermembrane space)|go:"GO:0007007"(inner mitochondrial membrane organization)|go:"GO:0016020"(membrane)|go:"GO:0042407"(cristae formation)|go:"GO:0051560"(mitochondrial calcium ion homeostasis)|go:"GO:0061617"(MICOS complex)|interpro:IPR019133|mint:Q16891|reactome:R-HSA-8949613|go:"GO:0140275"(MIB complex)|refseq:XP_016858683.1|dip:DIP-32517N - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/10/21 2020/11/06 rogid:RC80jQqKw4ekVFudqz/IunWCEMA9606 rogid:WypdAh4p5IjofFakBmSBwTIWWEs9606 rigid:319IsGV1oRp3OLZk5khzgtmEExU false enhanced green fluorescent protein tag:n-n|sufficient binding region:1776-1820 - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q2TAZ0 uniprotkb:Q8N766 intact:EBI-2514077|intact:EBI-28978291|uniprotkb:Q8TAI8|uniprotkb:O43154|uniprotkb:Q14DM2|uniprotkb:Q7Z6K8|uniprotkb:Q6ZTV2|uniprotkb:Q96HH7|uniprotkb:Q8IVY5|ensembl:ENSP00000366475 intact:EBI-1044442|ensembl:ENSP00000420608|uniprotkb:Q14700|uniprotkb:Q63HL0|uniprotkb:Q63HL3|uniprotkb:Q8NBH8|uniprotkb:A8K6F3|uniprotkb:Q5TG62 psi-mi:atg2a_human(display_long)|uniprotkb:ATG2A(gene name)|psi-mi:ATG2A(display_short)|uniprotkb:KIAA0404(gene name synonym) psi-mi:emc1_human(display_long)|uniprotkb:EMC1(gene name)|psi-mi:EMC1(display_short)|uniprotkb:KIAA0090(gene name synonym)|uniprotkb:PSEC0263(orf name) psi-mi:"MI:0030"(cross-linking study) Tang et al. (2019) imex:IM-28478|pubmed:31412244 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-26443127|imex:IM-28478-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:XP_011543165.1|ensembl:ENSP00000366475|ensembl:ENST00000421419|ensembl:ENSP00000410522|refseq:NP_055919.2|ensembl:ENSG00000110046(gene)|ensembl:ENST00000377264(transcript)|go:"GO:0000045"(autophagosome assembly)|go:"GO:0000407"(phagophore assembly site)|go:"GO:0000422"(autophagy of mitochondrion)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005811"(lipid droplet)|go:"GO:0019898"(extrinsic component of membrane)|go:"GO:0032266"(phosphatidylinositol-3-phosphate binding)|go:"GO:0034045"(phagophore assembly site membrane)|go:"GO:0034727"(piecemeal microautophagy of the nucleus)|go:"GO:0044805"(late nucleophagy)|interpro:IPR015412(ATG2, C-terminal)|interpro:IPR026849|interpro:IPR026854|rcsb pdb:6KLR|go:"GO:0061709"(reticulophagy) go:"GO:0045050"(protein insertion into ER membrane by stop-transfer membrane-anchor sequence)|ensembl:ENSG00000127463(gene)|ensembl:ENST00000477853(transcript)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030176"(integral component of endoplasmic reticulum membrane)|go:"GO:0071816"(tail-anchored membrane protein insertion into ER membrane)|go:"GO:0032991"(protein-containing complex)|go:"GO:0072546"(EMC complex)|interpro:IPR002372(Pyrrolo-quinoline quinone)|interpro:IPR011047(Quinonprotein alcohol dehydrogenase-like)|interpro:IPR011678(Protein of unknown function DUF1620)|interpro:IPR026895|mint:Q8N766|rcsb pdb:6WW7|rcsb pdb:6Z3W|rcsb pdb:7ADO|rcsb pdb:7ADP|refseq:NP_055862.1|refseq:NP_001258356.1|refseq:NP_001258357.1|refseq:NP_001258358.1 - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/10/21 2020/11/06 rogid:RC80jQqKw4ekVFudqz/IunWCEMA9606 rogid:ccxmkDoQwso1qb0UMHePqqRYcnU9606 rigid:319IsGV1oRp3OLZk5khzgtmEExU false enhanced green fluorescent protein tag:n-n|sufficient binding region:1776-1820 - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q2TAZ0 uniprotkb:P35232 intact:EBI-2514077|intact:EBI-28978291|uniprotkb:Q8TAI8|uniprotkb:O43154|uniprotkb:Q14DM2|uniprotkb:Q7Z6K8|uniprotkb:Q6ZTV2|uniprotkb:Q96HH7|uniprotkb:Q8IVY5|ensembl:ENSP00000366475 intact:EBI-354213|uniprotkb:Q4VBQ0|uniprotkb:B4DY47|ensembl:ENSP00000300408|ensembl:ENSP00000393320|ensembl:ENSP00000422182|ensembl:ENSP00000425035|ensembl:ENSP00000426433|ensembl:ENSP00000479488|ensembl:ENSP00000484113 psi-mi:atg2a_human(display_long)|uniprotkb:ATG2A(gene name)|psi-mi:ATG2A(display_short)|uniprotkb:KIAA0404(gene name synonym) psi-mi:phb_human(display_long)|uniprotkb:PHB(gene name)|psi-mi:PHB(display_short)|uniprotkb:PHB1(gene name synonym) psi-mi:"MI:0030"(cross-linking study) Tang et al. (2019) imex:IM-28478|pubmed:31412244 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-26443127|imex:IM-28478-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:XP_011543165.1|ensembl:ENSP00000366475|ensembl:ENST00000421419|ensembl:ENSP00000410522|refseq:NP_055919.2|ensembl:ENSG00000110046(gene)|ensembl:ENST00000377264(transcript)|go:"GO:0000045"(autophagosome assembly)|go:"GO:0000407"(phagophore assembly site)|go:"GO:0000422"(autophagy of mitochondrion)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005811"(lipid droplet)|go:"GO:0019898"(extrinsic component of membrane)|go:"GO:0032266"(phosphatidylinositol-3-phosphate binding)|go:"GO:0034045"(phagophore assembly site membrane)|go:"GO:0034727"(piecemeal microautophagy of the nucleus)|go:"GO:0044805"(late nucleophagy)|interpro:IPR015412(ATG2, C-terminal)|interpro:IPR026849|interpro:IPR026854|rcsb pdb:6KLR|go:"GO:0061709"(reticulophagy) refseq:NP_001268426.1|refseq:NP_002625.1|refseq:NP_001268425.1|refseq:NP_001268644.1|refseq:XP_016880252.1|dip:DIP-24248N|ensembl:ENSG00000167085(gene)|ensembl:ENST00000300408(transcript)|ensembl:ENST00000419140(transcript)|ensembl:ENST00000504124(transcript)|ensembl:ENST00000511832(transcript)|ensembl:ENST00000512041(transcript)|ensembl:ENST00000614445(transcript)|ensembl:ENST00000617874(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0001649"(osteoblast differentiation)|go:"GO:0001850"(complement component C3a binding)|go:"GO:0001851"(complement component C3b binding)|go:"GO:0002639"(positive regulation of immunoglobulin production)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005769"(early endosome)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0007005"(mitochondrion organization)|go:"GO:0007165"(signal transduction)|go:"GO:0007202"(activation of phospholipase C activity)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0009986"(cell surface)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010942"(positive regulation of cell death)|go:"GO:0010944"(negative regulation of transcription by competitive promoter binding)|go:"GO:0016020"(membrane)|go:"GO:0016575"(histone deacetylation)|go:"GO:0019899"(enzyme binding)|go:"GO:0023035"(CD40 signaling pathway)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0031871"(proteinase activated receptor binding)|go:"GO:0032740"(positive regulation of interleukin-17 production)|go:"GO:0035632"(mitochondrial prohibitin complex)|go:"GO:0039529"(RIG-I signaling pathway)|go:"GO:0042113"(B cell activation)|go:"GO:0042177"(negative regulation of protein catabolic process)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0044830"(modulation by host of viral RNA genome replication)|go:"GO:0045745"(positive regulation of G protein-coupled receptor signaling pathway)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045917"(positive regulation of complement activation)|go:"GO:0046718"(viral entry into host cell)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0048661"(positive regulation of smooth muscle cell proliferation)|go:"GO:0050821"(protein stabilization)|go:"GO:0050847"(progesterone receptor signaling pathway)|go:"GO:0051897"(positive regulation of protein kinase B signaling)|go:"GO:0060766"(negative regulation of androgen receptor signaling pathway)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070373"(negative regulation of ERK1 and ERK2 cascade)|go:"GO:0070374"(positive regulation of ERK1 and ERK2 cascade)|go:"GO:0071354"(cellular response to interleukin-6)|go:"GO:0071897"(DNA biosynthetic process)|go:"GO:0072538"(T-helper 17 type immune response)|go:"GO:0140374"(antiviral innate immune response)|go:"GO:1901224"(positive regulation of NIK/NF-kappaB signaling)|go:"GO:1990051"(activation of protein kinase C activity)|go:"GO:2000323"(negative regulation of glucocorticoid receptor signaling pathway)|interpro:IPR000163(Prohibitin)|interpro:IPR001107(Band 7 protein)|interpro:IPR036013|mint:P35232|rcsb pdb:1LU7|reactome:R-HSA-5673000|reactome:R-HSA-6802946|reactome:R-HSA-6802955|reactome:R-HSA-8949664|reactome:R-HSA-9649948 - - - figure legend:Table S1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/10/21 2020/11/06 rogid:RC80jQqKw4ekVFudqz/IunWCEMA9606 rogid:aIJj/q/3JKXuEVRELjKJb2SjCKQ9606 rigid:319IsGV1oRp3OLZk5khzgtmEExU false enhanced green fluorescent protein tag:n-n|sufficient binding region:1776-1820 - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:O96008 uniprotkb:Q2TAZ0 intact:EBI-1057581|uniprotkb:Q86VW4|uniprotkb:Q8WY09|uniprotkb:Q8WY10|uniprotkb:Q8WY11|uniprotkb:Q9BR95|uniprotkb:A0A024R0P9|ensembl:ENSP00000252487|ensembl:ENSP00000385184|ensembl:ENSP00000410339 intact:EBI-2514077|intact:EBI-28978291|uniprotkb:Q8TAI8|uniprotkb:O43154|uniprotkb:Q14DM2|uniprotkb:Q7Z6K8|uniprotkb:Q6ZTV2|uniprotkb:Q96HH7|uniprotkb:Q8IVY5|ensembl:ENSP00000366475 psi-mi:tom40_human(display_long)|uniprotkb:TOMM40(gene name)|psi-mi:TOMM40(display_short)|uniprotkb:PEREC1(gene name synonym)|uniprotkb:TOM40(gene name synonym)|uniprotkb:C19orf1(gene name synonym)|uniprotkb:Translocase of outer membrane 40 kDa subunit homolog(gene name synonym)|uniprotkb:Protein Haymaker(gene name synonym)|uniprotkb:p38.5(gene name synonym) psi-mi:atg2a_human(display_long)|uniprotkb:ATG2A(gene name)|psi-mi:ATG2A(display_short)|uniprotkb:KIAA0404(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Tang et al. (2019) imex:IM-28478|pubmed:31412244 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26443285|imex:IM-28478-3 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001122388.1|refseq:NP_001122389.1|refseq:NP_006105.1|ensembl:ENSG00000130204(gene)|ensembl:ENST00000252487(transcript)|ensembl:ENST00000405636(transcript)|ensembl:ENST00000426677(transcript)|go:"GO:0005739"(mitochondrion)|go:"GO:0005742"(mitochondrial outer membrane translocase complex)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005829"(cytosol)|go:"GO:0006626"(protein targeting to mitochondrion)|go:"GO:0006811"(ion transport)|go:"GO:0008320"(protein transmembrane transporter activity)|go:"GO:0015288"(porin activity)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030150"(protein import into mitochondrial matrix)|go:"GO:0031307"(integral component of mitochondrial outer membrane)|go:"GO:0044233"(mitochondria-associated endoplasmic reticulum membrane)|go:"GO:0046930"(pore complex)|interpro:IPR023614|interpro:IPR027246|interpro:IPR037930|rcsb pdb:7CK6|rcsb pdb:7CP9|reactome:R-HSA-1268020|reactome:R-HSA-5205685|go:"GO:0005741"(mitochondrial outer membrane) refseq:XP_011543165.1|ensembl:ENSP00000366475|ensembl:ENST00000421419|ensembl:ENSP00000410522|refseq:NP_055919.2|ensembl:ENSG00000110046(gene)|ensembl:ENST00000377264(transcript)|go:"GO:0000045"(autophagosome assembly)|go:"GO:0000407"(phagophore assembly site)|go:"GO:0000422"(autophagy of mitochondrion)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005811"(lipid droplet)|go:"GO:0019898"(extrinsic component of membrane)|go:"GO:0032266"(phosphatidylinositol-3-phosphate binding)|go:"GO:0034045"(phagophore assembly site membrane)|go:"GO:0034727"(piecemeal microautophagy of the nucleus)|go:"GO:0044805"(late nucleophagy)|interpro:IPR015412(ATG2, C-terminal)|interpro:IPR026849|interpro:IPR026854|rcsb pdb:6KLR|go:"GO:0061709"(reticulophagy) - - - figure legend:3B-H, 5C, Supp. figure 5A/B/C,6E|comment:The interaction of Atg2A with TOM40 was impaired by the loss of TOM70. Depletion of upstream Atg13 had little effect on the interaction of Atg2A with TOM40.|agonist:nutrient starvation|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/10/21 2020/11/06 rogid:BBV//Cb2ekmDNGHNrZuAXRgS++Y9606 rogid:RC80jQqKw4ekVFudqz/IunWCEMA9606 rigid:yxc0RG66N3cRZumyc9Dn19jynGg false - sufficient binding region:1776-1820|enhanced green fluorescent protein tag:n-n|mutation decreasing interaction strength:1777-1777,1780-1780,1784-1784|mutation disrupting interaction strength:1800-1800,1804-1804,1798-1798|mutation decreasing interaction strength:1777-1777,1780-1780,1784-1784,1798-1798,1800-1800,1804-1804 - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:Q7Z3C6 uniprotkb:Q2TAZ0 intact:EBI-727146|uniprotkb:Q6P0N7|uniprotkb:Q7Z317|uniprotkb:Q7Z320|uniprotkb:Q8NDK6|uniprotkb:Q8WU65|uniprotkb:Q9BVL5|uniprotkb:Q9H6L1|uniprotkb:Q9HAG7|uniprotkb:Q3ZAQ6|ensembl:ENSP00000355173|ensembl:ENSP00000379983|ensembl:ENSP00000386710 intact:EBI-2514077|intact:EBI-28978291|uniprotkb:Q8TAI8|uniprotkb:O43154|uniprotkb:Q14DM2|uniprotkb:Q7Z6K8|uniprotkb:Q6ZTV2|uniprotkb:Q96HH7|uniprotkb:Q8IVY5|ensembl:ENSP00000366475 psi-mi:atg9a_human(display_long)|uniprotkb:APG9-like 1(gene name synonym)|uniprotkb:ATG9A(gene name)|psi-mi:ATG9A(display_short)|uniprotkb:APG9L1(gene name synonym)|uniprotkb:mATG9(gene name synonym) psi-mi:atg2a_human(display_long)|uniprotkb:ATG2A(gene name)|psi-mi:ATG2A(display_short)|uniprotkb:KIAA0404(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Tang et al. (2019) imex:IM-28478|pubmed:31412244 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26443395|imex:IM-28478-7 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001070666.1|refseq:NP_076990.4|ensembl:ENSG00000198925(gene)|ensembl:ENST00000361242(transcript)|ensembl:ENST00000396761(transcript)|ensembl:ENST00000409618(transcript)|go:"GO:0000045"(autophagosome assembly)|go:"GO:0000407"(phagophore assembly site)|go:"GO:0000422"(autophagy of mitochondrion)|go:"GO:0005768"(endosome)|go:"GO:0005770"(late endosome)|go:"GO:0005776"(autophagosome)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0015031"(protein transport)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0031902"(late endosome membrane)|go:"GO:0034497"(protein localization to phagophore assembly site)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0044805"(late nucleophagy)|go:"GO:0055037"(recycling endosome)|interpro:IPR007241(Autophagy protein 99)|mint:Q7Z3C6|rcsb pdb:6WQZ|rcsb pdb:6WR4|rcsb pdb:7JLO|rcsb pdb:7JLP|rcsb pdb:7JLQ|reactome:R-HSA-1632852 refseq:XP_011543165.1|ensembl:ENSP00000366475|ensembl:ENST00000421419|ensembl:ENSP00000410522|refseq:NP_055919.2|ensembl:ENSG00000110046(gene)|ensembl:ENST00000377264(transcript)|go:"GO:0000045"(autophagosome assembly)|go:"GO:0000407"(phagophore assembly site)|go:"GO:0000422"(autophagy of mitochondrion)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005811"(lipid droplet)|go:"GO:0019898"(extrinsic component of membrane)|go:"GO:0032266"(phosphatidylinositol-3-phosphate binding)|go:"GO:0034045"(phagophore assembly site membrane)|go:"GO:0034727"(piecemeal microautophagy of the nucleus)|go:"GO:0044805"(late nucleophagy)|interpro:IPR015412(ATG2, C-terminal)|interpro:IPR026849|interpro:IPR026854|rcsb pdb:6KLR|go:"GO:0061709"(reticulophagy) - - - figure legend:Supp. figure 5D|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/10/21 2020/11/06 rogid:arvq+TjXETr14g/FkOITnLfYVh89606 rogid:RC80jQqKw4ekVFudqz/IunWCEMA9606 rigid:I6nicXSVfHUip/C4yYbxQfIScZw false - enhanced green fluorescent protein tag:n-n - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:Q2TAZ0 uniprotkb:O96008 intact:EBI-2514077|intact:EBI-28978291|uniprotkb:Q8TAI8|uniprotkb:O43154|uniprotkb:Q14DM2|uniprotkb:Q7Z6K8|uniprotkb:Q6ZTV2|uniprotkb:Q96HH7|uniprotkb:Q8IVY5|ensembl:ENSP00000366475 intact:EBI-1057581|uniprotkb:Q86VW4|uniprotkb:Q8WY09|uniprotkb:Q8WY10|uniprotkb:Q8WY11|uniprotkb:Q9BR95|uniprotkb:A0A024R0P9|ensembl:ENSP00000252487|ensembl:ENSP00000385184|ensembl:ENSP00000410339 psi-mi:atg2a_human(display_long)|uniprotkb:ATG2A(gene name)|psi-mi:ATG2A(display_short)|uniprotkb:KIAA0404(gene name synonym) psi-mi:tom40_human(display_long)|uniprotkb:TOMM40(gene name)|psi-mi:TOMM40(display_short)|uniprotkb:PEREC1(gene name synonym)|uniprotkb:TOM40(gene name synonym)|uniprotkb:C19orf1(gene name synonym)|uniprotkb:Translocase of outer membrane 40 kDa subunit homolog(gene name synonym)|uniprotkb:Protein Haymaker(gene name synonym)|uniprotkb:p38.5(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Tang et al. (2019) imex:IM-28478|pubmed:31412244 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-26443420|imex:IM-28478-9 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:XP_011543165.1|ensembl:ENSP00000366475|ensembl:ENST00000421419|ensembl:ENSP00000410522|refseq:NP_055919.2|ensembl:ENSG00000110046(gene)|ensembl:ENST00000377264(transcript)|go:"GO:0000045"(autophagosome assembly)|go:"GO:0000407"(phagophore assembly site)|go:"GO:0000422"(autophagy of mitochondrion)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005811"(lipid droplet)|go:"GO:0019898"(extrinsic component of membrane)|go:"GO:0032266"(phosphatidylinositol-3-phosphate binding)|go:"GO:0034045"(phagophore assembly site membrane)|go:"GO:0034727"(piecemeal microautophagy of the nucleus)|go:"GO:0044805"(late nucleophagy)|interpro:IPR015412(ATG2, C-terminal)|interpro:IPR026849|interpro:IPR026854|rcsb pdb:6KLR|go:"GO:0061709"(reticulophagy) refseq:NP_001122388.1|refseq:NP_001122389.1|refseq:NP_006105.1|ensembl:ENSG00000130204(gene)|ensembl:ENST00000252487(transcript)|ensembl:ENST00000405636(transcript)|ensembl:ENST00000426677(transcript)|go:"GO:0005739"(mitochondrion)|go:"GO:0005742"(mitochondrial outer membrane translocase complex)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005829"(cytosol)|go:"GO:0006626"(protein targeting to mitochondrion)|go:"GO:0006811"(ion transport)|go:"GO:0008320"(protein transmembrane transporter activity)|go:"GO:0015288"(porin activity)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030150"(protein import into mitochondrial matrix)|go:"GO:0031307"(integral component of mitochondrial outer membrane)|go:"GO:0044233"(mitochondria-associated endoplasmic reticulum membrane)|go:"GO:0046930"(pore complex)|interpro:IPR023614|interpro:IPR027246|interpro:IPR037930|rcsb pdb:7CK6|rcsb pdb:7CP9|reactome:R-HSA-1268020|reactome:R-HSA-5205685|go:"GO:0005741"(mitochondrial outer membrane) - - - figure legend:Supp. figure 7B|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/10/21 2020/11/06 rogid:RC80jQqKw4ekVFudqz/IunWCEMA9606 rogid:BBV//Cb2ekmDNGHNrZuAXRgS++Y9606 rigid:kuFWPLtVDSHwvwpfh/DXWGGW6uA false enhanced green fluorescent protein tag:n-n - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:Q2TAZ0 uniprotkb:Q7Z3C6 intact:EBI-2514077|intact:EBI-28978291|uniprotkb:Q8TAI8|uniprotkb:O43154|uniprotkb:Q14DM2|uniprotkb:Q7Z6K8|uniprotkb:Q6ZTV2|uniprotkb:Q96HH7|uniprotkb:Q8IVY5|ensembl:ENSP00000366475 intact:EBI-727146|uniprotkb:Q6P0N7|uniprotkb:Q7Z317|uniprotkb:Q7Z320|uniprotkb:Q8NDK6|uniprotkb:Q8WU65|uniprotkb:Q9BVL5|uniprotkb:Q9H6L1|uniprotkb:Q9HAG7|uniprotkb:Q3ZAQ6|ensembl:ENSP00000355173|ensembl:ENSP00000379983|ensembl:ENSP00000386710 psi-mi:atg2a_human(display_long)|uniprotkb:ATG2A(gene name)|psi-mi:ATG2A(display_short)|uniprotkb:KIAA0404(gene name synonym) psi-mi:atg9a_human(display_long)|uniprotkb:APG9-like 1(gene name synonym)|uniprotkb:ATG9A(gene name)|psi-mi:ATG9A(display_short)|uniprotkb:APG9L1(gene name synonym)|uniprotkb:mATG9(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Tang et al. (2019) imex:IM-28478|pubmed:31412244 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-26443420|imex:IM-28478-9 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:XP_011543165.1|ensembl:ENSP00000366475|ensembl:ENST00000421419|ensembl:ENSP00000410522|refseq:NP_055919.2|ensembl:ENSG00000110046(gene)|ensembl:ENST00000377264(transcript)|go:"GO:0000045"(autophagosome assembly)|go:"GO:0000407"(phagophore assembly site)|go:"GO:0000422"(autophagy of mitochondrion)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005811"(lipid droplet)|go:"GO:0019898"(extrinsic component of membrane)|go:"GO:0032266"(phosphatidylinositol-3-phosphate binding)|go:"GO:0034045"(phagophore assembly site membrane)|go:"GO:0034727"(piecemeal microautophagy of the nucleus)|go:"GO:0044805"(late nucleophagy)|interpro:IPR015412(ATG2, C-terminal)|interpro:IPR026849|interpro:IPR026854|rcsb pdb:6KLR|go:"GO:0061709"(reticulophagy) refseq:NP_001070666.1|refseq:NP_076990.4|ensembl:ENSG00000198925(gene)|ensembl:ENST00000361242(transcript)|ensembl:ENST00000396761(transcript)|ensembl:ENST00000409618(transcript)|go:"GO:0000045"(autophagosome assembly)|go:"GO:0000407"(phagophore assembly site)|go:"GO:0000422"(autophagy of mitochondrion)|go:"GO:0005768"(endosome)|go:"GO:0005770"(late endosome)|go:"GO:0005776"(autophagosome)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0015031"(protein transport)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0031902"(late endosome membrane)|go:"GO:0034497"(protein localization to phagophore assembly site)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0044805"(late nucleophagy)|go:"GO:0055037"(recycling endosome)|interpro:IPR007241(Autophagy protein 99)|mint:Q7Z3C6|rcsb pdb:6WQZ|rcsb pdb:6WR4|rcsb pdb:7JLO|rcsb pdb:7JLP|rcsb pdb:7JLQ|reactome:R-HSA-1632852 - - - figure legend:Supp. figure 7B|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/10/21 2020/11/06 rogid:RC80jQqKw4ekVFudqz/IunWCEMA9606 rogid:arvq+TjXETr14g/FkOITnLfYVh89606 rigid:kuFWPLtVDSHwvwpfh/DXWGGW6uA false enhanced green fluorescent protein tag:n-n - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:Q7Z3C6 uniprotkb:Q2TAZ0 intact:EBI-727146|uniprotkb:Q6P0N7|uniprotkb:Q7Z317|uniprotkb:Q7Z320|uniprotkb:Q8NDK6|uniprotkb:Q8WU65|uniprotkb:Q9BVL5|uniprotkb:Q9H6L1|uniprotkb:Q9HAG7|uniprotkb:Q3ZAQ6|ensembl:ENSP00000355173|ensembl:ENSP00000379983|ensembl:ENSP00000386710 intact:EBI-2514077|intact:EBI-28978291|uniprotkb:Q8TAI8|uniprotkb:O43154|uniprotkb:Q14DM2|uniprotkb:Q7Z6K8|uniprotkb:Q6ZTV2|uniprotkb:Q96HH7|uniprotkb:Q8IVY5|ensembl:ENSP00000366475 psi-mi:atg9a_human(display_long)|uniprotkb:APG9-like 1(gene name synonym)|uniprotkb:ATG9A(gene name)|psi-mi:ATG9A(display_short)|uniprotkb:APG9L1(gene name synonym)|uniprotkb:mATG9(gene name synonym) psi-mi:atg2a_human(display_long)|uniprotkb:ATG2A(gene name)|psi-mi:ATG2A(display_short)|uniprotkb:KIAA0404(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Tang et al. (2019) imex:IM-28478|pubmed:31412244 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26443429|imex:IM-28478-11 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001070666.1|refseq:NP_076990.4|ensembl:ENSG00000198925(gene)|ensembl:ENST00000361242(transcript)|ensembl:ENST00000396761(transcript)|ensembl:ENST00000409618(transcript)|go:"GO:0000045"(autophagosome assembly)|go:"GO:0000407"(phagophore assembly site)|go:"GO:0000422"(autophagy of mitochondrion)|go:"GO:0005768"(endosome)|go:"GO:0005770"(late endosome)|go:"GO:0005776"(autophagosome)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0015031"(protein transport)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0031902"(late endosome membrane)|go:"GO:0034497"(protein localization to phagophore assembly site)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0044805"(late nucleophagy)|go:"GO:0055037"(recycling endosome)|interpro:IPR007241(Autophagy protein 99)|mint:Q7Z3C6|rcsb pdb:6WQZ|rcsb pdb:6WR4|rcsb pdb:7JLO|rcsb pdb:7JLP|rcsb pdb:7JLQ|reactome:R-HSA-1632852 refseq:XP_011543165.1|ensembl:ENSP00000366475|ensembl:ENST00000421419|ensembl:ENSP00000410522|refseq:NP_055919.2|ensembl:ENSG00000110046(gene)|ensembl:ENST00000377264(transcript)|go:"GO:0000045"(autophagosome assembly)|go:"GO:0000407"(phagophore assembly site)|go:"GO:0000422"(autophagy of mitochondrion)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005811"(lipid droplet)|go:"GO:0019898"(extrinsic component of membrane)|go:"GO:0032266"(phosphatidylinositol-3-phosphate binding)|go:"GO:0034045"(phagophore assembly site membrane)|go:"GO:0034727"(piecemeal microautophagy of the nucleus)|go:"GO:0044805"(late nucleophagy)|interpro:IPR015412(ATG2, C-terminal)|interpro:IPR026849|interpro:IPR026854|rcsb pdb:6KLR|go:"GO:0061709"(reticulophagy) - - - figure legend:Supp. figure 7B|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/10/21 2020/11/06 rogid:arvq+TjXETr14g/FkOITnLfYVh89606 rogid:RC80jQqKw4ekVFudqz/IunWCEMA9606 rigid:I6nicXSVfHUip/C4yYbxQfIScZw false - enhanced green fluorescent protein tag:n-n|necessary binding region:237-431 - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:Q7Z3C6 uniprotkb:Q2TAZ0 intact:EBI-727146|uniprotkb:Q6P0N7|uniprotkb:Q7Z317|uniprotkb:Q7Z320|uniprotkb:Q8NDK6|uniprotkb:Q8WU65|uniprotkb:Q9BVL5|uniprotkb:Q9H6L1|uniprotkb:Q9HAG7|uniprotkb:Q3ZAQ6|ensembl:ENSP00000355173|ensembl:ENSP00000379983|ensembl:ENSP00000386710 intact:EBI-2514077|intact:EBI-28978291|uniprotkb:Q8TAI8|uniprotkb:O43154|uniprotkb:Q14DM2|uniprotkb:Q7Z6K8|uniprotkb:Q6ZTV2|uniprotkb:Q96HH7|uniprotkb:Q8IVY5|ensembl:ENSP00000366475 psi-mi:atg9a_human(display_long)|uniprotkb:APG9-like 1(gene name synonym)|uniprotkb:ATG9A(gene name)|psi-mi:ATG9A(display_short)|uniprotkb:APG9L1(gene name synonym)|uniprotkb:mATG9(gene name synonym) psi-mi:atg2a_human(display_long)|uniprotkb:ATG2A(gene name)|psi-mi:ATG2A(display_short)|uniprotkb:KIAA0404(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Tang et al. (2019) imex:IM-28478|pubmed:31412244 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26443669|imex:IM-28478-14 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001070666.1|refseq:NP_076990.4|ensembl:ENSG00000198925(gene)|ensembl:ENST00000361242(transcript)|ensembl:ENST00000396761(transcript)|ensembl:ENST00000409618(transcript)|go:"GO:0000045"(autophagosome assembly)|go:"GO:0000407"(phagophore assembly site)|go:"GO:0000422"(autophagy of mitochondrion)|go:"GO:0005768"(endosome)|go:"GO:0005770"(late endosome)|go:"GO:0005776"(autophagosome)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0015031"(protein transport)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0031902"(late endosome membrane)|go:"GO:0034497"(protein localization to phagophore assembly site)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0044805"(late nucleophagy)|go:"GO:0055037"(recycling endosome)|interpro:IPR007241(Autophagy protein 99)|mint:Q7Z3C6|rcsb pdb:6WQZ|rcsb pdb:6WR4|rcsb pdb:7JLO|rcsb pdb:7JLP|rcsb pdb:7JLQ|reactome:R-HSA-1632852 refseq:XP_011543165.1|ensembl:ENSP00000366475|ensembl:ENST00000421419|ensembl:ENSP00000410522|refseq:NP_055919.2|ensembl:ENSG00000110046(gene)|ensembl:ENST00000377264(transcript)|go:"GO:0000045"(autophagosome assembly)|go:"GO:0000407"(phagophore assembly site)|go:"GO:0000422"(autophagy of mitochondrion)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005811"(lipid droplet)|go:"GO:0019898"(extrinsic component of membrane)|go:"GO:0032266"(phosphatidylinositol-3-phosphate binding)|go:"GO:0034045"(phagophore assembly site membrane)|go:"GO:0034727"(piecemeal microautophagy of the nucleus)|go:"GO:0044805"(late nucleophagy)|interpro:IPR015412(ATG2, C-terminal)|interpro:IPR026849|interpro:IPR026854|rcsb pdb:6KLR|go:"GO:0061709"(reticulophagy) - - - figure legend:Supp. figure 3B|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/10/21 2020/11/09 rogid:arvq+TjXETr14g/FkOITnLfYVh89606 rogid:RC80jQqKw4ekVFudqz/IunWCEMA9606 rigid:I6nicXSVfHUip/C4yYbxQfIScZw false glutathione s tranferase tag:?-? enhanced green fluorescent protein tag:n-n|mutation disrupting interaction strength:1395-1397 - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:O96008 uniprotkb:Q2TAZ0 intact:EBI-1057581|uniprotkb:Q86VW4|uniprotkb:Q8WY09|uniprotkb:Q8WY10|uniprotkb:Q8WY11|uniprotkb:Q9BR95|uniprotkb:A0A024R0P9|ensembl:ENSP00000252487|ensembl:ENSP00000385184|ensembl:ENSP00000410339 intact:EBI-2514077|intact:EBI-28978291|uniprotkb:Q8TAI8|uniprotkb:O43154|uniprotkb:Q14DM2|uniprotkb:Q7Z6K8|uniprotkb:Q6ZTV2|uniprotkb:Q96HH7|uniprotkb:Q8IVY5|ensembl:ENSP00000366475 psi-mi:tom40_human(display_long)|uniprotkb:TOMM40(gene name)|psi-mi:TOMM40(display_short)|uniprotkb:PEREC1(gene name synonym)|uniprotkb:TOM40(gene name synonym)|uniprotkb:C19orf1(gene name synonym)|uniprotkb:Translocase of outer membrane 40 kDa subunit homolog(gene name synonym)|uniprotkb:Protein Haymaker(gene name synonym)|uniprotkb:p38.5(gene name synonym) psi-mi:atg2a_human(display_long)|uniprotkb:ATG2A(gene name)|psi-mi:ATG2A(display_short)|uniprotkb:KIAA0404(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Tang et al. (2019) imex:IM-28478|pubmed:31412244 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26597325|imex:IM-28478-21 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001122388.1|refseq:NP_001122389.1|refseq:NP_006105.1|ensembl:ENSG00000130204(gene)|ensembl:ENST00000252487(transcript)|ensembl:ENST00000405636(transcript)|ensembl:ENST00000426677(transcript)|go:"GO:0005739"(mitochondrion)|go:"GO:0005742"(mitochondrial outer membrane translocase complex)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005829"(cytosol)|go:"GO:0006626"(protein targeting to mitochondrion)|go:"GO:0006811"(ion transport)|go:"GO:0008320"(protein transmembrane transporter activity)|go:"GO:0015288"(porin activity)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030150"(protein import into mitochondrial matrix)|go:"GO:0031307"(integral component of mitochondrial outer membrane)|go:"GO:0044233"(mitochondria-associated endoplasmic reticulum membrane)|go:"GO:0046930"(pore complex)|interpro:IPR023614|interpro:IPR027246|interpro:IPR037930|rcsb pdb:7CK6|rcsb pdb:7CP9|reactome:R-HSA-1268020|reactome:R-HSA-5205685|go:"GO:0005741"(mitochondrial outer membrane) refseq:XP_011543165.1|ensembl:ENSP00000366475|ensembl:ENST00000421419|ensembl:ENSP00000410522|refseq:NP_055919.2|ensembl:ENSG00000110046(gene)|ensembl:ENST00000377264(transcript)|go:"GO:0000045"(autophagosome assembly)|go:"GO:0000407"(phagophore assembly site)|go:"GO:0000422"(autophagy of mitochondrion)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005811"(lipid droplet)|go:"GO:0019898"(extrinsic component of membrane)|go:"GO:0032266"(phosphatidylinositol-3-phosphate binding)|go:"GO:0034045"(phagophore assembly site membrane)|go:"GO:0034727"(piecemeal microautophagy of the nucleus)|go:"GO:0044805"(late nucleophagy)|interpro:IPR015412(ATG2, C-terminal)|interpro:IPR026849|interpro:IPR026854|rcsb pdb:6KLR|go:"GO:0061709"(reticulophagy) intact:EBI-26443679(see-also) - - figure legend:Supp. figure 6E|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/10/21 2021/01/19 rogid:BBV//Cb2ekmDNGHNrZuAXRgS++Y9606 rogid:RC80jQqKw4ekVFudqz/IunWCEMA9606 rigid:yxc0RG66N3cRZumyc9Dn19jynGg false - enhanced green fluorescent protein tag:n-n|mutation:1395-1397 - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:O96008 uniprotkb:Q2TAZ0 intact:EBI-1057581|uniprotkb:Q86VW4|uniprotkb:Q8WY09|uniprotkb:Q8WY10|uniprotkb:Q8WY11|uniprotkb:Q9BR95|uniprotkb:A0A024R0P9|ensembl:ENSP00000252487|ensembl:ENSP00000385184|ensembl:ENSP00000410339 intact:EBI-2514077|intact:EBI-28978291|uniprotkb:Q8TAI8|uniprotkb:O43154|uniprotkb:Q14DM2|uniprotkb:Q7Z6K8|uniprotkb:Q6ZTV2|uniprotkb:Q96HH7|uniprotkb:Q8IVY5|ensembl:ENSP00000366475 psi-mi:tom40_human(display_long)|uniprotkb:TOMM40(gene name)|psi-mi:TOMM40(display_short)|uniprotkb:PEREC1(gene name synonym)|uniprotkb:TOM40(gene name synonym)|uniprotkb:C19orf1(gene name synonym)|uniprotkb:Translocase of outer membrane 40 kDa subunit homolog(gene name synonym)|uniprotkb:Protein Haymaker(gene name synonym)|uniprotkb:p38.5(gene name synonym) psi-mi:atg2a_human(display_long)|uniprotkb:ATG2A(gene name)|psi-mi:ATG2A(display_short)|uniprotkb:KIAA0404(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Tang et al. (2019) imex:IM-28478|pubmed:31412244 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26443369|imex:IM-28478-5 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001122388.1|refseq:NP_001122389.1|refseq:NP_006105.1|ensembl:ENSG00000130204(gene)|ensembl:ENST00000252487(transcript)|ensembl:ENST00000405636(transcript)|ensembl:ENST00000426677(transcript)|go:"GO:0005739"(mitochondrion)|go:"GO:0005742"(mitochondrial outer membrane translocase complex)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005829"(cytosol)|go:"GO:0006626"(protein targeting to mitochondrion)|go:"GO:0006811"(ion transport)|go:"GO:0008320"(protein transmembrane transporter activity)|go:"GO:0015288"(porin activity)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030150"(protein import into mitochondrial matrix)|go:"GO:0031307"(integral component of mitochondrial outer membrane)|go:"GO:0044233"(mitochondria-associated endoplasmic reticulum membrane)|go:"GO:0046930"(pore complex)|interpro:IPR023614|interpro:IPR027246|interpro:IPR037930|rcsb pdb:7CK6|rcsb pdb:7CP9|reactome:R-HSA-1268020|reactome:R-HSA-5205685|go:"GO:0005741"(mitochondrial outer membrane) refseq:XP_011543165.1|ensembl:ENSP00000366475|ensembl:ENST00000421419|ensembl:ENSP00000410522|refseq:NP_055919.2|ensembl:ENSG00000110046(gene)|ensembl:ENST00000377264(transcript)|go:"GO:0000045"(autophagosome assembly)|go:"GO:0000407"(phagophore assembly site)|go:"GO:0000422"(autophagy of mitochondrion)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005811"(lipid droplet)|go:"GO:0019898"(extrinsic component of membrane)|go:"GO:0032266"(phosphatidylinositol-3-phosphate binding)|go:"GO:0034045"(phagophore assembly site membrane)|go:"GO:0034727"(piecemeal microautophagy of the nucleus)|go:"GO:0044805"(late nucleophagy)|interpro:IPR015412(ATG2, C-terminal)|interpro:IPR026849|interpro:IPR026854|rcsb pdb:6KLR|go:"GO:0061709"(reticulophagy) - - - figure legend:Supp. figure 5A|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/10/21 2020/11/06 rogid:BBV//Cb2ekmDNGHNrZuAXRgS++Y9606 rogid:RC80jQqKw4ekVFudqz/IunWCEMA9606 rigid:yxc0RG66N3cRZumyc9Dn19jynGg false - - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:Q68FE2 uniprotkb:Q2TAZ0 intact:EBI-7091482|ensembl:ENSMUSP00000159170|intact:UNK-5419756|intact:EBI-8390940|intact:UNK-5468806|uniprotkb:Q3ZAQ4 intact:EBI-2514077|intact:EBI-28978291|uniprotkb:Q8TAI8|uniprotkb:O43154|uniprotkb:Q14DM2|uniprotkb:Q7Z6K8|uniprotkb:Q6ZTV2|uniprotkb:Q96HH7|uniprotkb:Q8IVY5|ensembl:ENSP00000366475 psi-mi:atg9a_mouse(display_long)|uniprotkb:Atg9a(gene name)|psi-mi:Atg9a(display_short)|uniprotkb:Apg9l1(gene name synonym)|uniprotkb:APG9-like 1(gene name synonym) psi-mi:atg2a_human(display_long)|uniprotkb:ATG2A(gene name)|psi-mi:ATG2A(display_short)|uniprotkb:KIAA0404(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Tang et al. (2019) imex:IM-28478|pubmed:31412244 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26443621|imex:IM-28478-12 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001275541.1|ensembl:ENSMUSG00000033124(gene)|ensembl:ENSMUST00000239085(transcript)|go:"GO:0000045"(autophagosome assembly)|go:"GO:0000407"(phagophore assembly site)|go:"GO:0000422"(autophagy of mitochondrion)|go:"GO:0005737"(cytoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005770"(late endosome)|go:"GO:0005776"(autophagosome)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0006914"(autophagy)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0015031"(protein transport)|go:"GO:0016021"(integral component of membrane)|go:"GO:0031902"(late endosome membrane)|go:"GO:0032688"(negative regulation of interferon-beta production)|go:"GO:0034067"(protein localization to Golgi apparatus)|go:"GO:0034497"(protein localization to phagophore assembly site)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0044805"(late nucleophagy)|go:"GO:0045087"(innate immune response)|go:"GO:0055037"(recycling endosome)|interpro:IPR007241(Autophagy protein 99)|reactome:R-MMU-1632852|mint:Q68FE2|refseq:NP_001003917.2 refseq:XP_011543165.1|ensembl:ENSP00000366475|ensembl:ENST00000421419|ensembl:ENSP00000410522|refseq:NP_055919.2|ensembl:ENSG00000110046(gene)|ensembl:ENST00000377264(transcript)|go:"GO:0000045"(autophagosome assembly)|go:"GO:0000407"(phagophore assembly site)|go:"GO:0000422"(autophagy of mitochondrion)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005811"(lipid droplet)|go:"GO:0019898"(extrinsic component of membrane)|go:"GO:0032266"(phosphatidylinositol-3-phosphate binding)|go:"GO:0034045"(phagophore assembly site membrane)|go:"GO:0034727"(piecemeal microautophagy of the nucleus)|go:"GO:0044805"(late nucleophagy)|interpro:IPR015412(ATG2, C-terminal)|interpro:IPR026849|interpro:IPR026854|rcsb pdb:6KLR|go:"GO:0061709"(reticulophagy) - comment:mint - figure legend:6A, 7B|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/10/21 2021/12/01 rogid:JXXrkgG3yJQKPuDs4y5dzrYh2w010090 rogid:RC80jQqKw4ekVFudqz/IunWCEMA9606 rigid:eqXHjgqrKxVsbP1/8B74UerTgpI false green fluorescent protein tag:?-? necessary binding region:237-431|myc tag:?-? - - psi-mi:"MI:0705"(anti tag western blot) psi-mi:"MI:0705"(anti tag western blot) uniprotkb:Q2TAZ0 uniprotkb:O96008 intact:EBI-2514077|intact:EBI-28978291|uniprotkb:Q8TAI8|uniprotkb:O43154|uniprotkb:Q14DM2|uniprotkb:Q7Z6K8|uniprotkb:Q6ZTV2|uniprotkb:Q96HH7|uniprotkb:Q8IVY5|ensembl:ENSP00000366475 intact:EBI-1057581|uniprotkb:Q86VW4|uniprotkb:Q8WY09|uniprotkb:Q8WY10|uniprotkb:Q8WY11|uniprotkb:Q9BR95|uniprotkb:A0A024R0P9|ensembl:ENSP00000252487|ensembl:ENSP00000385184|ensembl:ENSP00000410339 psi-mi:atg2a_human(display_long)|uniprotkb:ATG2A(gene name)|psi-mi:ATG2A(display_short)|uniprotkb:KIAA0404(gene name synonym) psi-mi:tom40_human(display_long)|uniprotkb:TOMM40(gene name)|psi-mi:TOMM40(display_short)|uniprotkb:PEREC1(gene name synonym)|uniprotkb:TOM40(gene name synonym)|uniprotkb:C19orf1(gene name synonym)|uniprotkb:Translocase of outer membrane 40 kDa subunit homolog(gene name synonym)|uniprotkb:Protein Haymaker(gene name synonym)|uniprotkb:p38.5(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Tang et al. (2019) imex:IM-28478|pubmed:31412244 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-26443679|imex:IM-28478-16 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:XP_011543165.1|ensembl:ENSP00000366475|ensembl:ENST00000421419|ensembl:ENSP00000410522|refseq:NP_055919.2|ensembl:ENSG00000110046(gene)|ensembl:ENST00000377264(transcript)|go:"GO:0000045"(autophagosome assembly)|go:"GO:0000407"(phagophore assembly site)|go:"GO:0000422"(autophagy of mitochondrion)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005811"(lipid droplet)|go:"GO:0019898"(extrinsic component of membrane)|go:"GO:0032266"(phosphatidylinositol-3-phosphate binding)|go:"GO:0034045"(phagophore assembly site membrane)|go:"GO:0034727"(piecemeal microautophagy of the nucleus)|go:"GO:0044805"(late nucleophagy)|interpro:IPR015412(ATG2, C-terminal)|interpro:IPR026849|interpro:IPR026854|rcsb pdb:6KLR|go:"GO:0061709"(reticulophagy) refseq:NP_001122388.1|refseq:NP_001122389.1|refseq:NP_006105.1|ensembl:ENSG00000130204(gene)|ensembl:ENST00000252487(transcript)|ensembl:ENST00000405636(transcript)|ensembl:ENST00000426677(transcript)|go:"GO:0005739"(mitochondrion)|go:"GO:0005742"(mitochondrial outer membrane translocase complex)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005829"(cytosol)|go:"GO:0006626"(protein targeting to mitochondrion)|go:"GO:0006811"(ion transport)|go:"GO:0008320"(protein transmembrane transporter activity)|go:"GO:0015288"(porin activity)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030150"(protein import into mitochondrial matrix)|go:"GO:0031307"(integral component of mitochondrial outer membrane)|go:"GO:0044233"(mitochondria-associated endoplasmic reticulum membrane)|go:"GO:0046930"(pore complex)|interpro:IPR023614|interpro:IPR027246|interpro:IPR037930|rcsb pdb:7CK6|rcsb pdb:7CP9|reactome:R-HSA-1268020|reactome:R-HSA-5205685|go:"GO:0005741"(mitochondrial outer membrane) intact:EBI-26443120(see-also)|intact:EBI-26443744(see-also) - - figure legend:Supp. figure 6E|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/10/21 2020/11/09 rogid:RC80jQqKw4ekVFudqz/IunWCEMA9606 rogid:BBV//Cb2ekmDNGHNrZuAXRgS++Y9606 rigid:HlUzgAbKVMVbS7fsD2tj6PvXXnE false enhanced green fluorescent protein tag:n-n|mutation with complex effect:1395-1397|mutation with complex effect:1798-1798,1777-1777,1780-1780,1784-1784,1800-1800,1804-1804 - - - psi-mi:"MI:0705"(anti tag western blot) psi-mi:"MI:0113"(western blot) uniprotkb:Q2TAZ0 uniprotkb:Q9Y484 intact:EBI-2514077|intact:EBI-28978291|uniprotkb:Q8TAI8|uniprotkb:O43154|uniprotkb:Q14DM2|uniprotkb:Q7Z6K8|uniprotkb:Q6ZTV2|uniprotkb:Q96HH7|uniprotkb:Q8IVY5|ensembl:ENSP00000366475 intact:EBI-2682844|uniprotkb:A6NGH5|uniprotkb:Q6IBS7|uniprotkb:B7WPI2|uniprotkb:Q5MNZ5|uniprotkb:Q96H03|uniprotkb:Q6NT94|ensembl:ENSP00000365551|ensembl:ENSP00000488972 psi-mi:atg2a_human(display_long)|uniprotkb:ATG2A(gene name)|psi-mi:ATG2A(display_short)|uniprotkb:KIAA0404(gene name synonym) psi-mi:wipi4_human(display_long)|uniprotkb:WDRX1(gene name synonym)|uniprotkb:WDRXI4(gene name synonym)|uniprotkb:WIPI4(gene name synonym)|uniprotkb:WD repeat-containing protein 45(gene name synonym)|uniprotkb:JM5(orf name)|uniprotkb:WDR45(gene name)|psi-mi:WDR45(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Tang et al. (2019) imex:IM-28478|pubmed:31412244 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-26443679|imex:IM-28478-16 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:XP_011543165.1|ensembl:ENSP00000366475|ensembl:ENST00000421419|ensembl:ENSP00000410522|refseq:NP_055919.2|ensembl:ENSG00000110046(gene)|ensembl:ENST00000377264(transcript)|go:"GO:0000045"(autophagosome assembly)|go:"GO:0000407"(phagophore assembly site)|go:"GO:0000422"(autophagy of mitochondrion)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005811"(lipid droplet)|go:"GO:0019898"(extrinsic component of membrane)|go:"GO:0032266"(phosphatidylinositol-3-phosphate binding)|go:"GO:0034045"(phagophore assembly site membrane)|go:"GO:0034727"(piecemeal microautophagy of the nucleus)|go:"GO:0044805"(late nucleophagy)|interpro:IPR015412(ATG2, C-terminal)|interpro:IPR026849|interpro:IPR026854|rcsb pdb:6KLR|go:"GO:0061709"(reticulophagy) refseq:NP_001025067.1|refseq:NP_009006.2|ensembl:ENSG00000196998(gene)|ensembl:ENST00000376372(transcript)|ensembl:ENST00000634944(transcript)|go:"GO:0000045"(autophagosome assembly)|go:"GO:0000407"(phagophore assembly site)|go:"GO:0000422"(autophagy of mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0006497"(protein lipidation)|go:"GO:0006914"(autophagy)|go:"GO:0009267"(cellular response to starvation)|go:"GO:0019898"(extrinsic component of membrane)|go:"GO:0019901"(protein kinase binding)|go:"GO:0032266"(phosphatidylinositol-3-phosphate binding)|go:"GO:0034045"(phagophore assembly site membrane)|go:"GO:0034497"(protein localization to phagophore assembly site)|go:"GO:0044804"(autophagy of nucleus)|go:"GO:0080025"(phosphatidylinositol-3,5-bisphosphate binding)|go:"GO:1901981"(phosphatidylinositol phosphate binding)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR032910|interpro:IPR036322|reactome:R-HSA-1632852 intact:EBI-26443120(see-also)|intact:EBI-26443744(see-also) - - figure legend:Supp. figure 6E|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/10/21 2020/11/09 rogid:RC80jQqKw4ekVFudqz/IunWCEMA9606 rogid:4SjRZZ6WlEK+pJBrZgqqTyD6h7A9606 rigid:HlUzgAbKVMVbS7fsD2tj6PvXXnE false enhanced green fluorescent protein tag:n-n|mutation with complex effect:1395-1397|mutation with complex effect:1798-1798,1777-1777,1780-1780,1784-1784,1800-1800,1804-1804 glutathione s tranferase tag:?-? - - psi-mi:"MI:0705"(anti tag western blot) psi-mi:"MI:0705"(anti tag western blot) uniprotkb:Q9Y484 uniprotkb:Q2TAZ0 intact:EBI-2682844|uniprotkb:A6NGH5|uniprotkb:Q6IBS7|uniprotkb:B7WPI2|uniprotkb:Q5MNZ5|uniprotkb:Q96H03|uniprotkb:Q6NT94|ensembl:ENSP00000365551|ensembl:ENSP00000488972 intact:EBI-2514077|intact:EBI-28978291|uniprotkb:Q8TAI8|uniprotkb:O43154|uniprotkb:Q14DM2|uniprotkb:Q7Z6K8|uniprotkb:Q6ZTV2|uniprotkb:Q96HH7|uniprotkb:Q8IVY5|ensembl:ENSP00000366475 psi-mi:wipi4_human(display_long)|uniprotkb:WDRX1(gene name synonym)|uniprotkb:WDRXI4(gene name synonym)|uniprotkb:WIPI4(gene name synonym)|uniprotkb:WD repeat-containing protein 45(gene name synonym)|uniprotkb:JM5(orf name)|uniprotkb:WDR45(gene name)|psi-mi:WDR45(display_short) psi-mi:atg2a_human(display_long)|uniprotkb:ATG2A(gene name)|psi-mi:ATG2A(display_short)|uniprotkb:KIAA0404(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Tang et al. (2019) imex:IM-28478|pubmed:31412244 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-26443744|imex:IM-28478-18 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001025067.1|refseq:NP_009006.2|ensembl:ENSG00000196998(gene)|ensembl:ENST00000376372(transcript)|ensembl:ENST00000634944(transcript)|go:"GO:0000045"(autophagosome assembly)|go:"GO:0000407"(phagophore assembly site)|go:"GO:0000422"(autophagy of mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0006497"(protein lipidation)|go:"GO:0006914"(autophagy)|go:"GO:0009267"(cellular response to starvation)|go:"GO:0019898"(extrinsic component of membrane)|go:"GO:0019901"(protein kinase binding)|go:"GO:0032266"(phosphatidylinositol-3-phosphate binding)|go:"GO:0034045"(phagophore assembly site membrane)|go:"GO:0034497"(protein localization to phagophore assembly site)|go:"GO:0044804"(autophagy of nucleus)|go:"GO:0080025"(phosphatidylinositol-3,5-bisphosphate binding)|go:"GO:1901981"(phosphatidylinositol phosphate binding)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR032910|interpro:IPR036322|reactome:R-HSA-1632852 refseq:XP_011543165.1|ensembl:ENSP00000366475|ensembl:ENST00000421419|ensembl:ENSP00000410522|refseq:NP_055919.2|ensembl:ENSG00000110046(gene)|ensembl:ENST00000377264(transcript)|go:"GO:0000045"(autophagosome assembly)|go:"GO:0000407"(phagophore assembly site)|go:"GO:0000422"(autophagy of mitochondrion)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005811"(lipid droplet)|go:"GO:0019898"(extrinsic component of membrane)|go:"GO:0032266"(phosphatidylinositol-3-phosphate binding)|go:"GO:0034045"(phagophore assembly site membrane)|go:"GO:0034727"(piecemeal microautophagy of the nucleus)|go:"GO:0044805"(late nucleophagy)|interpro:IPR015412(ATG2, C-terminal)|interpro:IPR026849|interpro:IPR026854|rcsb pdb:6KLR|go:"GO:0061709"(reticulophagy) intact:EBI-26443679(see-also) - - figure legend:Supp. figure 6E|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/10/21 2020/11/09 rogid:4SjRZZ6WlEK+pJBrZgqqTyD6h7A9606 rogid:RC80jQqKw4ekVFudqz/IunWCEMA9606 rigid:nQUiGdkr69dpr3VY8LFt+OLoqG4 false glutathione s tranferase tag:?-? enhanced green fluorescent protein tag:n-n|mutation:1798-1798,1777-1777,1780-1780,1784-1784,1800-1800,1804-1804 - - psi-mi:"MI:0705"(anti tag western blot) psi-mi:"MI:0705"(anti tag western blot) uniprotkb:Q2TAZ0 uniprotkb:O96008 intact:EBI-2514077|intact:EBI-28978291|uniprotkb:Q8TAI8|uniprotkb:O43154|uniprotkb:Q14DM2|uniprotkb:Q7Z6K8|uniprotkb:Q6ZTV2|uniprotkb:Q96HH7|uniprotkb:Q8IVY5|ensembl:ENSP00000366475 intact:EBI-1057581|uniprotkb:Q86VW4|uniprotkb:Q8WY09|uniprotkb:Q8WY10|uniprotkb:Q8WY11|uniprotkb:Q9BR95|uniprotkb:A0A024R0P9|ensembl:ENSP00000252487|ensembl:ENSP00000385184|ensembl:ENSP00000410339 psi-mi:atg2a_human(display_long)|uniprotkb:ATG2A(gene name)|psi-mi:ATG2A(display_short)|uniprotkb:KIAA0404(gene name synonym) psi-mi:tom40_human(display_long)|uniprotkb:TOMM40(gene name)|psi-mi:TOMM40(display_short)|uniprotkb:PEREC1(gene name synonym)|uniprotkb:TOM40(gene name synonym)|uniprotkb:C19orf1(gene name synonym)|uniprotkb:Translocase of outer membrane 40 kDa subunit homolog(gene name synonym)|uniprotkb:Protein Haymaker(gene name synonym)|uniprotkb:p38.5(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Tang et al. (2019) imex:IM-28478|pubmed:31412244 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-26597263|imex:IM-28478-19 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:XP_011543165.1|ensembl:ENSP00000366475|ensembl:ENST00000421419|ensembl:ENSP00000410522|refseq:NP_055919.2|ensembl:ENSG00000110046(gene)|ensembl:ENST00000377264(transcript)|go:"GO:0000045"(autophagosome assembly)|go:"GO:0000407"(phagophore assembly site)|go:"GO:0000422"(autophagy of mitochondrion)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005811"(lipid droplet)|go:"GO:0019898"(extrinsic component of membrane)|go:"GO:0032266"(phosphatidylinositol-3-phosphate binding)|go:"GO:0034045"(phagophore assembly site membrane)|go:"GO:0034727"(piecemeal microautophagy of the nucleus)|go:"GO:0044805"(late nucleophagy)|interpro:IPR015412(ATG2, C-terminal)|interpro:IPR026849|interpro:IPR026854|rcsb pdb:6KLR|go:"GO:0061709"(reticulophagy) refseq:NP_001122388.1|refseq:NP_001122389.1|refseq:NP_006105.1|ensembl:ENSG00000130204(gene)|ensembl:ENST00000252487(transcript)|ensembl:ENST00000405636(transcript)|ensembl:ENST00000426677(transcript)|go:"GO:0005739"(mitochondrion)|go:"GO:0005742"(mitochondrial outer membrane translocase complex)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005829"(cytosol)|go:"GO:0006626"(protein targeting to mitochondrion)|go:"GO:0006811"(ion transport)|go:"GO:0008320"(protein transmembrane transporter activity)|go:"GO:0015288"(porin activity)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030150"(protein import into mitochondrial matrix)|go:"GO:0031307"(integral component of mitochondrial outer membrane)|go:"GO:0044233"(mitochondria-associated endoplasmic reticulum membrane)|go:"GO:0046930"(pore complex)|interpro:IPR023614|interpro:IPR027246|interpro:IPR037930|rcsb pdb:7CK6|rcsb pdb:7CP9|reactome:R-HSA-1268020|reactome:R-HSA-5205685|go:"GO:0005741"(mitochondrial outer membrane) intact:EBI-26443679(see-also) - - figure legend:Supp. figure 6E|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/10/21 2021/01/19 rogid:RC80jQqKw4ekVFudqz/IunWCEMA9606 rogid:BBV//Cb2ekmDNGHNrZuAXRgS++Y9606 rigid:HlUzgAbKVMVbS7fsD2tj6PvXXnE false enhanced green fluorescent protein tag:n-n - - - psi-mi:"MI:0705"(anti tag western blot) psi-mi:"MI:0113"(western blot) uniprotkb:Q2TAZ0 uniprotkb:Q9Y484 intact:EBI-2514077|intact:EBI-28978291|uniprotkb:Q8TAI8|uniprotkb:O43154|uniprotkb:Q14DM2|uniprotkb:Q7Z6K8|uniprotkb:Q6ZTV2|uniprotkb:Q96HH7|uniprotkb:Q8IVY5|ensembl:ENSP00000366475 intact:EBI-2682844|uniprotkb:A6NGH5|uniprotkb:Q6IBS7|uniprotkb:B7WPI2|uniprotkb:Q5MNZ5|uniprotkb:Q96H03|uniprotkb:Q6NT94|ensembl:ENSP00000365551|ensembl:ENSP00000488972 psi-mi:atg2a_human(display_long)|uniprotkb:ATG2A(gene name)|psi-mi:ATG2A(display_short)|uniprotkb:KIAA0404(gene name synonym) psi-mi:wipi4_human(display_long)|uniprotkb:WDRX1(gene name synonym)|uniprotkb:WDRXI4(gene name synonym)|uniprotkb:WIPI4(gene name synonym)|uniprotkb:WD repeat-containing protein 45(gene name synonym)|uniprotkb:JM5(orf name)|uniprotkb:WDR45(gene name)|psi-mi:WDR45(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Tang et al. (2019) imex:IM-28478|pubmed:31412244 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-26597263|imex:IM-28478-19 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:XP_011543165.1|ensembl:ENSP00000366475|ensembl:ENST00000421419|ensembl:ENSP00000410522|refseq:NP_055919.2|ensembl:ENSG00000110046(gene)|ensembl:ENST00000377264(transcript)|go:"GO:0000045"(autophagosome assembly)|go:"GO:0000407"(phagophore assembly site)|go:"GO:0000422"(autophagy of mitochondrion)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005811"(lipid droplet)|go:"GO:0019898"(extrinsic component of membrane)|go:"GO:0032266"(phosphatidylinositol-3-phosphate binding)|go:"GO:0034045"(phagophore assembly site membrane)|go:"GO:0034727"(piecemeal microautophagy of the nucleus)|go:"GO:0044805"(late nucleophagy)|interpro:IPR015412(ATG2, C-terminal)|interpro:IPR026849|interpro:IPR026854|rcsb pdb:6KLR|go:"GO:0061709"(reticulophagy) refseq:NP_001025067.1|refseq:NP_009006.2|ensembl:ENSG00000196998(gene)|ensembl:ENST00000376372(transcript)|ensembl:ENST00000634944(transcript)|go:"GO:0000045"(autophagosome assembly)|go:"GO:0000407"(phagophore assembly site)|go:"GO:0000422"(autophagy of mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0006497"(protein lipidation)|go:"GO:0006914"(autophagy)|go:"GO:0009267"(cellular response to starvation)|go:"GO:0019898"(extrinsic component of membrane)|go:"GO:0019901"(protein kinase binding)|go:"GO:0032266"(phosphatidylinositol-3-phosphate binding)|go:"GO:0034045"(phagophore assembly site membrane)|go:"GO:0034497"(protein localization to phagophore assembly site)|go:"GO:0044804"(autophagy of nucleus)|go:"GO:0080025"(phosphatidylinositol-3,5-bisphosphate binding)|go:"GO:1901981"(phosphatidylinositol phosphate binding)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR032910|interpro:IPR036322|reactome:R-HSA-1632852 intact:EBI-26443679(see-also) - - figure legend:Supp. figure 6E|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/10/21 2021/01/19 rogid:RC80jQqKw4ekVFudqz/IunWCEMA9606 rogid:4SjRZZ6WlEK+pJBrZgqqTyD6h7A9606 rigid:HlUzgAbKVMVbS7fsD2tj6PvXXnE false enhanced green fluorescent protein tag:n-n glutathione s tranferase tag:?-? - - psi-mi:"MI:0705"(anti tag western blot) psi-mi:"MI:0705"(anti tag western blot)