#ID(s) interactor A ID(s) interactor B Alt. ID(s) interactor A Alt. ID(s) interactor B Alias(es) interactor A Alias(es) interactor B Interaction detection method(s) Publication 1st author(s) Publication Identifier(s) Taxid interactor A Taxid interactor B Interaction type(s) Source database(s) Interaction identifier(s) Confidence value(s) Expansion method(s) Biological role(s) interactor A Biological role(s) interactor B Experimental role(s) interactor A Experimental role(s) interactor B Type(s) interactor A Type(s) interactor B Xref(s) interactor A Xref(s) interactor B Interaction Xref(s) Annotation(s) interactor A Annotation(s) interactor B Interaction annotation(s) Host organism(s) Interaction parameter(s) Creation date Update date Checksum(s) interactor A Checksum(s) interactor B Interaction Checksum(s) Negative Feature(s) interactor A Feature(s) interactor B Stoichiometry(s) interactor A Stoichiometry(s) interactor B Identification method participant A Identification method participant B uniprotkb:H9E912 uniprotkb:H9E912 intact:EBI-25623612 intact:EBI-25623612 psi-mi:h9e912_hhv1(display_long)|uniprotkb:UL6(gene name)|psi-mi:UL6(display_short)|uniprotkb:HHV1gp011(orf name) psi-mi:h9e912_hhv1(display_long)|uniprotkb:UL6(gene name)|psi-mi:UL6(display_short)|uniprotkb:HHV1gp011(orf name) psi-mi:"MI:0410"(3D electron microscopy) Yun-Tao et al. (2019) pubmed:31142842|imex:IM-28054 taxid:10298(hhv1)|taxid:10298(Human herpesvirus 1) taxid:10298(hhv1)|taxid:10298(Human herpesvirus 1) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0465"(DIP) intact:EBI-25623610|imex:IM-28054-1|wwpdb:6OD7|emdb:EMD-9862|emdb:EMD-9864|emdb:EMD-9861|emdb:EMD-9863 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0006323"(DNA packaging)|go:"GO:0019076"(viral release from host cell)|go:"GO:0042025"(host cell nucleus)|rcsb pdb:6OD7|interpro:IPR002660(Herpesvirus UL6 like) go:"GO:0006323"(DNA packaging)|go:"GO:0019076"(viral release from host cell)|go:"GO:0042025"(host cell nucleus)|rcsb pdb:6OD7|interpro:IPR002660(Herpesvirus UL6 like) - - - figure legend:Extended Data Table 1|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9534(chlae-vero)|taxid:9534("Chlorocebus (Cercopithecus) aethiops kidney cells") - 2020/05/29 2020/06/08 rogid:jW//CQTJDkmtmoQX7tEwIIywmkI10298 rogid:jW//CQTJDkmtmoQX7tEwIIywmkI10298 rigid:dsVgeEMyyth29rx2j/FqhUIIVqU false - - 12 0 psi-mi:"MI:0396"(predetermined participant)|psi-mi:"MI:2287"(identification by structure determination) psi-mi:"MI:0396"(predetermined participant)|psi-mi:"MI:2287"(identification by structure determination) uniprotkb:D3YPI2 uniprotkb:F8REV0 intact:EBI-25638763 intact:EBI-25638751 psi-mi:d3ypi2_hhv1(display_long)|uniprotkb:UL25(gene name)|psi-mi:UL25(display_short)|uniprotkb:CVC2(gene name synonym)|uniprotkb:HHV1gp036(orf name)|uniprotkb:hmpv205_0025(orf name)|uniprotkb:hmpv208_0025(orf name)|uniprotkb:hmpv214_0025(orf name) psi-mi:f8rev0_hhv1(display_long)|uniprotkb:UL17(gene name)|psi-mi:UL17(display_short)|uniprotkb:CVC1(gene name synonym)|uniprotkb:HHV1gp024(orf name) psi-mi:"MI:0410"(3D electron microscopy) Yun-Tao et al. (2019) pubmed:31142842|imex:IM-28054 taxid:10298(hhv1)|taxid:10298(Human herpesvirus 1) taxid:10298(hhv1)|taxid:10298(Human herpesvirus 1) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0465"(DIP) intact:EBI-25638719|imex:IM-28054-3|wwpdb:6ODM|emdb:EMD-9860 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0019028"(viral capsid)|go:"GO:0019072"(viral genome packaging)|go:"GO:0019076"(viral release from host cell)|go:"GO:0042025"(host cell nucleus)|go:"GO:0046718"(viral entry into host cell)|go:"GO:0075732"(viral penetration into host nucleus)|rcsb pdb:6ODM|interpro:IPR002493(Herpesvirus UL25 protein) go:"GO:0006323"(DNA packaging)|go:"GO:0019028"(viral capsid)|go:"GO:0019076"(viral release from host cell)|go:"GO:0042025"(host cell nucleus)|rcsb pdb:6ODM|interpro:IPR007640(Herpesvirus UL17 protein) - - - figure legend:Extended Data Table 1|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9534(chlae-vero)|taxid:9534("Chlorocebus (Cercopithecus) aethiops kidney cells") - 2020/05/29 2020/06/08 rogid:EmwKG4MkD7b6clq4kdtE4dzSKho10298 rogid:jpHy2SjAwN9RrOORroPt2o8LroU10298 rigid:YLuYf2/7rbaGlBHvNvBd5WpygXs false - - 2 1 psi-mi:"MI:0396"(predetermined participant)|psi-mi:"MI:2287"(identification by structure determination) psi-mi:"MI:0396"(predetermined participant)|psi-mi:"MI:2287"(identification by structure determination) uniprotkb:D3YPI2 uniprotkb:G8H8D9 intact:EBI-25638763 intact:EBI-25638734 psi-mi:d3ypi2_hhv1(display_long)|uniprotkb:UL25(gene name)|psi-mi:UL25(display_short)|uniprotkb:CVC2(gene name synonym)|uniprotkb:HHV1gp036(orf name)|uniprotkb:hmpv205_0025(orf name)|uniprotkb:hmpv208_0025(orf name)|uniprotkb:hmpv214_0025(orf name) psi-mi:g8h8d9_hhv1(display_long)|uniprotkb:UL18(gene name)|psi-mi:UL18(display_short)|uniprotkb:TRX2(gene name synonym)|uniprotkb:UL18-UL20.6(gene name synonym)|uniprotkb:HHV1gp030(orf name)|uniprotkb:hmpv207_0017(orf name)|uniprotkb:hmpv213_0017(orf name)|uniprotkb:hmpv214_0018(orf name) psi-mi:"MI:0410"(3D electron microscopy) Yun-Tao et al. (2019) pubmed:31142842|imex:IM-28054 taxid:10298(hhv1)|taxid:10298(Human herpesvirus 1) taxid:10298(hhv1)|taxid:10298(Human herpesvirus 1) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0465"(DIP) intact:EBI-25638719|imex:IM-28054-3|wwpdb:6ODM|emdb:EMD-9860 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0019028"(viral capsid)|go:"GO:0019072"(viral genome packaging)|go:"GO:0019076"(viral release from host cell)|go:"GO:0042025"(host cell nucleus)|go:"GO:0046718"(viral entry into host cell)|go:"GO:0075732"(viral penetration into host nucleus)|rcsb pdb:6ODM|interpro:IPR002493(Herpesvirus UL25 protein) go:"GO:0005198"(structural molecule activity)|go:"GO:0019028"(viral capsid)|go:"GO:0019069"(viral capsid assembly)|go:"GO:0042025"(host cell nucleus)|rcsb pdb:6CGR|refseq:YP_009137092.1|rcsb pdb:6ODM|interpro:IPR002690(Herpesvirus VP23-like capsid protein) - - - figure legend:Extended Data Table 1|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9534(chlae-vero)|taxid:9534("Chlorocebus (Cercopithecus) aethiops kidney cells") - 2020/05/29 2020/06/08 rogid:EmwKG4MkD7b6clq4kdtE4dzSKho10298 rogid:7zi0KlbNZbJe1c7CfqLe06zIUrE10298 rigid:YLuYf2/7rbaGlBHvNvBd5WpygXs false - - 2 4 psi-mi:"MI:0396"(predetermined participant)|psi-mi:"MI:2287"(identification by structure determination) psi-mi:"MI:0396"(predetermined participant)|psi-mi:"MI:2287"(identification by structure determination) uniprotkb:D3YPI2 uniprotkb:H9E925 intact:EBI-25638763 intact:EBI-25638818 psi-mi:d3ypi2_hhv1(display_long)|uniprotkb:UL25(gene name)|psi-mi:UL25(display_short)|uniprotkb:CVC2(gene name synonym)|uniprotkb:HHV1gp036(orf name)|uniprotkb:hmpv205_0025(orf name)|uniprotkb:hmpv208_0025(orf name)|uniprotkb:hmpv214_0025(orf name) psi-mi:h9e925_hhv1(display_long)|uniprotkb:UL19(gene name)|psi-mi:UL19(display_short)|uniprotkb:MCP(gene name synonym)|uniprotkb:HHV1gp028(orf name) psi-mi:"MI:0410"(3D electron microscopy) Yun-Tao et al. (2019) pubmed:31142842|imex:IM-28054 taxid:10298(hhv1)|taxid:10298(Human herpesvirus 1) taxid:10298(hhv1)|taxid:10298(Human herpesvirus 1) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0465"(DIP) intact:EBI-25638719|imex:IM-28054-3|wwpdb:6ODM|emdb:EMD-9860 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0019028"(viral capsid)|go:"GO:0019072"(viral genome packaging)|go:"GO:0019076"(viral release from host cell)|go:"GO:0042025"(host cell nucleus)|go:"GO:0046718"(viral entry into host cell)|go:"GO:0075732"(viral penetration into host nucleus)|rcsb pdb:6ODM|interpro:IPR002493(Herpesvirus UL25 protein) go:"GO:0005198"(structural molecule activity)|go:"GO:0039622"(T=16 icosahedral viral capsid)|go:"GO:0042025"(host cell nucleus)|rcsb pdb:6ODM|interpro:IPR000912("Herpesvirus major capsid protein (MCP)")|interpro:IPR023233 - - - figure legend:Extended Data Table 1|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9534(chlae-vero)|taxid:9534("Chlorocebus (Cercopithecus) aethiops kidney cells") - 2020/05/29 2020/06/08 rogid:EmwKG4MkD7b6clq4kdtE4dzSKho10298 rogid:5WZV9NFYuQZ8IVjUmoCO+y2r5tM10298 rigid:YLuYf2/7rbaGlBHvNvBd5WpygXs false - - 2 4 psi-mi:"MI:0396"(predetermined participant)|psi-mi:"MI:2287"(identification by structure determination) psi-mi:"MI:0396"(predetermined participant)|psi-mi:"MI:2287"(identification by structure determination) uniprotkb:D3YPI2 uniprotkb:I1UYK0 intact:EBI-25638763 intact:EBI-25638799 psi-mi:d3ypi2_hhv1(display_long)|uniprotkb:UL25(gene name)|psi-mi:UL25(display_short)|uniprotkb:CVC2(gene name synonym)|uniprotkb:HHV1gp036(orf name)|uniprotkb:hmpv205_0025(orf name)|uniprotkb:hmpv208_0025(orf name)|uniprotkb:hmpv214_0025(orf name) psi-mi:i1uyk0_hhv1(display_long)|uniprotkb:UL36(gene name)|psi-mi:UL36(display_short) psi-mi:"MI:0410"(3D electron microscopy) Yun-Tao et al. (2019) pubmed:31142842|imex:IM-28054 taxid:10298(hhv1)|taxid:10298(Human herpesvirus 1) taxid:10298(hhv1)|taxid:10298(Human herpesvirus 1) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0465"(DIP) intact:EBI-25638719|imex:IM-28054-3|wwpdb:6ODM|emdb:EMD-9860 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0019028"(viral capsid)|go:"GO:0019072"(viral genome packaging)|go:"GO:0019076"(viral release from host cell)|go:"GO:0042025"(host cell nucleus)|go:"GO:0046718"(viral entry into host cell)|go:"GO:0075732"(viral penetration into host nucleus)|rcsb pdb:6ODM|interpro:IPR002493(Herpesvirus UL25 protein) go:"GO:0004843"(thiol-dependent deubiquitinase)|go:"GO:0019033"(viral tegument)|go:"GO:0019784"(NEDD8-specific protease activity)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039648"(modulation by virus of host protein ubiquitination)|go:"GO:0039693"(viral DNA genome replication)|go:"GO:0042025"(host cell nucleus)|rcsb pdb:6ODM|interpro:IPR005210(Herpesvirus UL36 tegument protein, central region)|interpro:IPR006928(Peptidase C76, herpesvirus UL36 UL36 deubiquitinylating peptidase)|interpro:IPR034702|interpro:IPR038765 - - - figure legend:Extended Data Table 1|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9534(chlae-vero)|taxid:9534("Chlorocebus (Cercopithecus) aethiops kidney cells") - 2020/05/29 2020/06/08 rogid:EmwKG4MkD7b6clq4kdtE4dzSKho10298 rogid:vDLqUKXBZvDFDgVSJa5V/ppVh6I10298 rigid:YLuYf2/7rbaGlBHvNvBd5WpygXs false - - 2 2 psi-mi:"MI:0396"(predetermined participant)|psi-mi:"MI:2287"(identification by structure determination) psi-mi:"MI:0396"(predetermined participant)|psi-mi:"MI:2287"(identification by structure determination) uniprotkb:D3YPI2 uniprotkb:Q1T724 intact:EBI-25638763 intact:EBI-25638721 psi-mi:d3ypi2_hhv1(display_long)|uniprotkb:UL25(gene name)|psi-mi:UL25(display_short)|uniprotkb:CVC2(gene name synonym)|uniprotkb:HHV1gp036(orf name)|uniprotkb:hmpv205_0025(orf name)|uniprotkb:hmpv208_0025(orf name)|uniprotkb:hmpv214_0025(orf name) psi-mi:q1t724_hhv1(display_long)|uniprotkb:UL38(gene name)|psi-mi:UL38(display_short)|uniprotkb:TRX1(gene name synonym)|uniprotkb:VP19C(gene name synonym)|uniprotkb:HHV1gp056(orf name) psi-mi:"MI:0410"(3D electron microscopy) Yun-Tao et al. (2019) pubmed:31142842|imex:IM-28054 taxid:10298(hhv1)|taxid:10298(Human herpesvirus 1) taxid:10298(hhv1)|taxid:10298(Human herpesvirus 1) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0465"(DIP) intact:EBI-25638719|imex:IM-28054-3|wwpdb:6ODM|emdb:EMD-9860 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0019028"(viral capsid)|go:"GO:0019072"(viral genome packaging)|go:"GO:0019076"(viral release from host cell)|go:"GO:0042025"(host cell nucleus)|go:"GO:0046718"(viral entry into host cell)|go:"GO:0075732"(viral penetration into host nucleus)|rcsb pdb:6ODM|interpro:IPR002493(Herpesvirus UL25 protein) go:"GO:0003677"(DNA binding)|go:"GO:0019028"(viral capsid)|go:"GO:0019069"(viral capsid assembly)|go:"GO:0042025"(host cell nucleus)|rcsb pdb:6ODM|interpro:IPR004999(Herpesvirus capsid shell protein VP19C) - - - figure legend:Extended Data Table 1|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9534(chlae-vero)|taxid:9534("Chlorocebus (Cercopithecus) aethiops kidney cells") - 2020/05/29 2020/06/08 rogid:EmwKG4MkD7b6clq4kdtE4dzSKho10298 rogid:BDpikd7hv9UWSba1/c2TR+Si7qM10298 rigid:YLuYf2/7rbaGlBHvNvBd5WpygXs false - - 2 2 psi-mi:"MI:0396"(predetermined participant)|psi-mi:"MI:2287"(identification by structure determination) psi-mi:"MI:0396"(predetermined participant)|psi-mi:"MI:2287"(identification by structure determination) uniprotkb:D3YPI2 uniprotkb:Q25BW6 intact:EBI-25638763 intact:EBI-25638780 psi-mi:d3ypi2_hhv1(display_long)|uniprotkb:UL25(gene name)|psi-mi:UL25(display_short)|uniprotkb:CVC2(gene name synonym)|uniprotkb:HHV1gp036(orf name)|uniprotkb:hmpv205_0025(orf name)|uniprotkb:hmpv208_0025(orf name)|uniprotkb:hmpv214_0025(orf name) psi-mi:q25bw6_hhv1(display_long)|uniprotkb:UL35(gene name)|psi-mi:UL35(display_short)|uniprotkb:SCP(gene name synonym)|uniprotkb:UL31.5-UL35(gene name synonym)|uniprotkb:HHV1gp052(orf name)|uniprotkb:hmpv205_0036(orf name)|uniprotkb:hmpv206_0036(orf name)|uniprotkb:hmpv207_0035(orf name)|uniprotkb:hmpv208_0036(orf name)|uniprotkb:hmpv213_0033(orf name)|uniprotkb:hmpv214_0036(orf name) psi-mi:"MI:0410"(3D electron microscopy) Yun-Tao et al. (2019) pubmed:31142842|imex:IM-28054 taxid:10298(hhv1)|taxid:10298(Human herpesvirus 1) taxid:10298(hhv1)|taxid:10298(Human herpesvirus 1) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0465"(DIP) intact:EBI-25638719|imex:IM-28054-3|wwpdb:6ODM|emdb:EMD-9860 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0019028"(viral capsid)|go:"GO:0019072"(viral genome packaging)|go:"GO:0019076"(viral release from host cell)|go:"GO:0042025"(host cell nucleus)|go:"GO:0046718"(viral entry into host cell)|go:"GO:0075732"(viral penetration into host nucleus)|rcsb pdb:6ODM|interpro:IPR002493(Herpesvirus UL25 protein) go:"GO:0019028"(viral capsid)|go:"GO:0042025"(host cell nucleus)|go:"GO:0016032"(viral process)|refseq:YP_009137110.1|rcsb pdb:6CGR|rcsb pdb:6ODM|interpro:IPR007584(Herpesvirus UL35) - - - figure legend:Extended Data Table 1|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9534(chlae-vero)|taxid:9534("Chlorocebus (Cercopithecus) aethiops kidney cells") - 2020/05/29 2020/06/08 rogid:EmwKG4MkD7b6clq4kdtE4dzSKho10298 rogid:VEJKzcMzD/lc0CHJw7iGxoo/7zU10298 rigid:YLuYf2/7rbaGlBHvNvBd5WpygXs false - - 2 4 psi-mi:"MI:0396"(predetermined participant)|psi-mi:"MI:2287"(identification by structure determination) psi-mi:"MI:0396"(predetermined participant)|psi-mi:"MI:2287"(identification by structure determination)