#ID(s) interactor A	ID(s) interactor B	Alt. ID(s) interactor A	Alt. ID(s) interactor B	Alias(es) interactor A	Alias(es) interactor B	Interaction detection method(s)	Publication 1st author(s)	Publication Identifier(s)	Taxid interactor A	Taxid interactor B	Interaction type(s)	Source database(s)	Interaction identifier(s)	Confidence value(s)	Expansion method(s)	Biological role(s) interactor A	Biological role(s) interactor B	Experimental role(s) interactor A	Experimental role(s) interactor B	Type(s) interactor A	Type(s) interactor B	Xref(s) interactor A	Xref(s) interactor B	Interaction Xref(s)	Annotation(s) interactor A	Annotation(s) interactor B	Interaction annotation(s)	Host organism(s)	Interaction parameter(s)	Creation date	Update date	Checksum(s) interactor A	Checksum(s) interactor B	Interaction Checksum(s)	Negative	Feature(s) interactor A	Feature(s) interactor B	Stoichiometry(s) interactor A	Stoichiometry(s) interactor B	Identification method participant A	Identification method participant B
uniprotkb:P97493-PRO_0000034151	uniprotkb:Q8K354	intact:EBI-26567598	intact:EBI-8321969|intact:MINT-4117620|ensembl:ENSMUSP00000047712	psi-mi:p97493-pro_0000034151(display_long)|uniprotkb:Thioredoxin-2(gene name synonym)|uniprotkb:Txn2(gene name)|psi-mi:Txn2(display_short)	psi-mi:cbr3_mouse(display_long)|uniprotkb:Cbr3(gene name)|psi-mi:Cbr3(display_short)|uniprotkb:NADPH-dependent carbonyl reductase 3(gene name synonym)	psi-mi:"MI:0096"(pull down)	Chasapis et al. (2019)	pubmed:31018154|imex:IM-28571	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26499412|imex:IM-28571-21	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	intact:EBI-8354432(chain-parent)	refseq:NP_766635.1|ensembl:ENSMUSG00000022947(gene)|ensembl:ENSMUST00000039620(transcript)|go:"GO:0000253"(3-keto sterol reductase activity)|go:"GO:0004090"("carbonyl reductase (NADPH) activity")|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0042376"(phylloquinone catabolic process)|go:"GO:0050890"(cognition)|go:"GO:0070402"(NADPH binding)|interpro:IPR002347(Glucose/ribitol dehydrogenase)|interpro:IPR020904|interpro:IPR036291|mint:Q8K354|reactome:R-MMU-211945	-	chain-seq-start:60|chain-seq-end:166	comment:mint	figure legend:ST1.1|comment:acid-eluted fraction|dataset:Rare diseases - Interactions investigated in the context of Rare genetic disease|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2020/12/04	2020/12/21	rogid:mvYK6+YgIN/WuGLBCWqsqPLfDyQ10090	rogid:7MDBEB8lGtUcG+neZ3a6Ed59foM10090	rigid:Y12P/8lD0zKvIbifDxV5fTMn1mU	false	mutation:34-34	-	-	-	psi-mi:"MI:0082"(peptide massfingerprinting)	psi-mi:"MI:0082"(peptide massfingerprinting)
uniprotkb:P97493-PRO_0000034151	uniprotkb:O88844	intact:EBI-26567598	intact:EBI-8317306|ensembl:ENSMUSP00000127307|ensembl:ENSMUSP00000095316|uniprotkb:Q3UAV7|intact:MINT-1859161	psi-mi:p97493-pro_0000034151(display_long)|uniprotkb:Thioredoxin-2(gene name synonym)|uniprotkb:Txn2(gene name)|psi-mi:Txn2(display_short)	psi-mi:idhc_mouse(display_long)|uniprotkb:Idh1(gene name)|psi-mi:Idh1(display_short)|uniprotkb:Cytosolic NADP-isocitrate dehydrogenase(gene name synonym)|uniprotkb:Oxalosuccinate decarboxylase(gene name synonym)|uniprotkb:"NADP(+)-specific ICDH"(gene name synonym)|uniprotkb:IDP(gene name synonym)	psi-mi:"MI:0096"(pull down)	Chasapis et al. (2019)	pubmed:31018154|imex:IM-28571	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26499412|imex:IM-28571-21	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	intact:EBI-8354432(chain-parent)	ensembl:ENSMUST00000097709(transcript)|ensembl:ENSMUST00000169032(transcript)|go:"GO:0000287"(magnesium ion binding)|go:"GO:0004448"(isocitrate dehydrogenase activity)|go:"GO:0004450"("isocitrate dehydrogenase (NADP+) activity")|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005777"(peroxisome)|go:"GO:0005829"(cytosol)|go:"GO:0006097"(glyoxylate cycle)|go:"GO:0006099"(tricarboxylic acid cycle)|go:"GO:0006102"(isocitrate metabolic process)|go:"GO:0006103"(2-oxoglutarate metabolic process)|go:"GO:0006739"(NADP metabolic process)|go:"GO:0006749"(glutathione metabolic process)|go:"GO:0006979"(response to oxidative stress)|go:"GO:0008585"(female gonad development)|go:"GO:0014070"(response to organic cyclic compound)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0048545"(response to steroid hormone)|go:"GO:0050661"(NADP binding)|go:"GO:0051287"(NAD binding)|go:"GO:0060696"(regulation of phospholipid catabolic process)|go:"GO:0071071"(regulation of phospholipid biosynthetic process)|interpro:IPR004790(Isocitrate dehydrogenase NADP-dependent, eukaryotic)|interpro:IPR019818|interpro:IPR024084|mint:O88844|rcsb pdb:5YZH|rcsb pdb:5YZI|reactome:R-MMU-389542|reactome:R-MMU-6798695|reactome:R-MMU-9033241|ensembl:ENSMUSG00000025950(gene)|refseq:NP_001104790.1|refseq:NP_034627.3	-	chain-seq-start:60|chain-seq-end:166	comment:mint	figure legend:ST1.1|comment:acid-eluted fraction|dataset:Rare diseases - Interactions investigated in the context of Rare genetic disease|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2020/12/04	2020/12/21	rogid:mvYK6+YgIN/WuGLBCWqsqPLfDyQ10090	rogid:Toc7c5pd1IUEj7JsoBe3+e2h4T810090	rigid:Y12P/8lD0zKvIbifDxV5fTMn1mU	false	mutation:34-34	-	-	-	psi-mi:"MI:0082"(peptide massfingerprinting)	psi-mi:"MI:0082"(peptide massfingerprinting)
uniprotkb:P97493-PRO_0000034151	uniprotkb:P56480	intact:EBI-26567598	intact:EBI-299482|ensembl:ENSMUSP00000026459|uniprotkb:Q0QEP4|uniprotkb:Q3TFD7|uniprotkb:Q3TIP9|uniprotkb:Q3TK44|uniprotkb:Q3TWD5|uniprotkb:Q3TX28|uniprotkb:Q3U6U4|uniprotkb:Q3U774|uniprotkb:Q3UB69|uniprotkb:Q3UF69|uniprotkb:Q8CI65|uniprotkb:Q8VEJ5|uniprotkb:Q9CTI7|uniprotkb:Q9CWX7	psi-mi:p97493-pro_0000034151(display_long)|uniprotkb:Thioredoxin-2(gene name synonym)|uniprotkb:Txn2(gene name)|psi-mi:Txn2(display_short)	psi-mi:atpb_mouse(display_long)|uniprotkb:Atp5f1b(gene name)|psi-mi:Atp5f1b(display_short)|uniprotkb:ATP synthase F1 subunit beta(gene name synonym)|uniprotkb:Atp5b(gene name synonym)	psi-mi:"MI:0096"(pull down)	Chasapis et al. (2019)	pubmed:31018154|imex:IM-28571	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26499412|imex:IM-28571-21	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	intact:EBI-8354432(chain-parent)	interpro:IPR024034|interpro:IPR027417|interpro:IPR036121|mint:P56480|reactome:R-MMU-1268020|reactome:R-MMU-163210|reactome:R-MMU-8949613|interpro:IPR020003|ensembl:ENSMUSG00000025393(gene)|ensembl:ENSMUST00000026459(transcript)|go:"GO:0000275"("mitochondrial proton-transporting ATP synthase complex, catalytic sector F(1)")|go:"GO:0001525"(angiogenesis)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005753"(mitochondrial proton-transporting ATP synthase complex)|go:"GO:0005886"(plasma membrane)|go:"GO:0006629"(lipid metabolic process)|go:"GO:0006754"(ATP biosynthetic process)|go:"GO:0006898"(receptor-mediated endocytosis)|go:"GO:0006933"(negative regulation of cell adhesion involved in substrate-bound cell migration)|go:"GO:0009986"(cell surface)|go:"GO:0016020"(membrane)|go:"GO:0030228"(lipoprotein particle receptor activity)|go:"GO:0031966"(mitochondrial membrane)|go:"GO:0042288"(MHC class I protein binding)|go:"GO:0042645"(mitochondrial nucleoid)|go:"GO:0042776"(mitochondrial ATP synthesis coupled proton transport)|go:"GO:0043209"(myelin sheath)|go:"GO:0043531"(ADP binding)|go:"GO:0043532"(angiostatin binding)|go:"GO:0043536"(positive regulation of blood vessel endothelial cell migration)|go:"GO:0045121"(membrane raft)|go:"GO:0045259"(proton-transporting ATP synthase complex)|go:"GO:0045261"("proton-transporting ATP synthase complex, catalytic core F(1)")|go:"GO:0046034"(ATP metabolic process)|go:"GO:0046933"(proton-transporting ATP synthase activity, rotational mechanism)|go:"GO:0046961"(proton-transporting ATPase activity, rotational mechanism)|go:"GO:0051453"(regulation of intracellular pH)|go:"GO:0098761"(cellular response to interleukin-7)|go:"GO:1902600"(proton transmembrane transport)|interpro:IPR000194(ATPase, F1/V1/A1 complex, alpha/beta subunit, nucleotide-binding)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR004100(ATPase, F1/V1/A1 complex, alpha/beta subunit, N-terminal)|interpro:IPR005722(ATPase, F1 complex, beta subunit)|go:"GO:0005524"(ATP binding)|refseq:NP_058054.2	-	chain-seq-start:60|chain-seq-end:166	-	figure legend:ST1.1|comment:acid-eluted fraction|dataset:Rare diseases - Interactions investigated in the context of Rare genetic disease|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2020/12/04	2020/12/21	rogid:mvYK6+YgIN/WuGLBCWqsqPLfDyQ10090	rogid:ihjn7GQ1ZSBfGcfwEAYSiCIuq+410090	rigid:Y12P/8lD0zKvIbifDxV5fTMn1mU	false	mutation:34-34	-	-	-	psi-mi:"MI:0082"(peptide massfingerprinting)	psi-mi:"MI:0082"(peptide massfingerprinting)
uniprotkb:P97493-PRO_0000034151	uniprotkb:Q03265	intact:EBI-26567598	intact:EBI-299884|ensembl:ENSMUSP00000026495|uniprotkb:Q3TFN0|uniprotkb:Q3THN8|uniprotkb:Q3TPR0|uniprotkb:Q3TPV3|uniprotkb:Q3TZU3|uniprotkb:Q3UIR7|uniprotkb:Q543Y6	psi-mi:p97493-pro_0000034151(display_long)|uniprotkb:Thioredoxin-2(gene name synonym)|uniprotkb:Txn2(gene name)|psi-mi:Txn2(display_short)	psi-mi:atpa_mouse(display_long)|uniprotkb:Atp5f1a(gene name)|psi-mi:Atp5f1a(display_short)|uniprotkb:ATP synthase F1 subunit alpha(gene name synonym)|uniprotkb:Atp5a1(gene name synonym)	psi-mi:"MI:0096"(pull down)	Chasapis et al. (2019)	pubmed:31018154|imex:IM-28571	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26499412|imex:IM-28571-21	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	intact:EBI-8354432(chain-parent)	go:"GO:0005634"(nucleus)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005753"(mitochondrial proton-transporting ATP synthase complex)|ensembl:ENSMUSG00000025428(gene)|ensembl:ENSMUST00000026495(transcript)|go:"GO:0000275"("mitochondrial proton-transporting ATP synthase complex, catalytic sector F(1)")|go:"GO:0001937"(negative regulation of endothelial cell proliferation)|go:"GO:0002020"(protease binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005754"(mitochondrial proton-transporting ATP synthase, catalytic core)|go:"GO:0005886"(plasma membrane)|go:"GO:0006629"(lipid metabolic process)|go:"GO:0006754"(ATP biosynthetic process)|go:"GO:0008180"(COP9 signalosome)|go:"GO:0009986"(cell surface)|go:"GO:0015986"(ATP synthesis coupled proton transport)|go:"GO:0016020"(membrane)|go:"GO:0042288"(MHC class I protein binding)|go:"GO:0042776"(mitochondrial ATP synthesis coupled proton transport)|go:"GO:0043209"(myelin sheath)|go:"GO:0043531"(ADP binding)|go:"GO:0043532"(angiostatin binding)|go:"GO:0043536"(positive regulation of blood vessel endothelial cell migration)|go:"GO:0045121"(membrane raft)|go:"GO:0045259"(proton-transporting ATP synthase complex)|go:"GO:0045261"("proton-transporting ATP synthase complex, catalytic core F(1)")|go:"GO:0046034"(ATP metabolic process)|go:"GO:0046933"(proton-transporting ATP synthase activity, rotational mechanism)|interpro:IPR000194(ATPase, F1/V1/A1 complex, alpha/beta subunit, nucleotide-binding)|interpro:IPR000793(ATPase, F1/V1/A1 complex, alpha/beta subunit, C-terminal)|interpro:IPR004100(ATPase, F1/V1/A1 complex, alpha/beta subunit, N-terminal)|interpro:IPR005294(ATPase, F1 complex, alpha subunit)|interpro:IPR020003|interpro:IPR023366|interpro:IPR027417|interpro:IPR033732|interpro:IPR036121|interpro:IPR038376|mint:Q03265|reactome:R-MMU-163210|reactome:R-MMU-8949613|refseq:NP_031531.1	-	chain-seq-start:60|chain-seq-end:166	-	figure legend:ST1.1|comment:acid-eluted fraction|dataset:Rare diseases - Interactions investigated in the context of Rare genetic disease|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2020/12/04	2020/12/21	rogid:mvYK6+YgIN/WuGLBCWqsqPLfDyQ10090	rogid:sBPTQwqC0dJTjZlZMKRzTSu6gHg10090	rigid:Y12P/8lD0zKvIbifDxV5fTMn1mU	false	mutation:34-34	-	-	-	psi-mi:"MI:0082"(peptide massfingerprinting)	psi-mi:"MI:0082"(peptide massfingerprinting)
uniprotkb:P97493-PRO_0000034151	uniprotkb:P17182	intact:EBI-26567598	intact:EBI-299507|ensembl:ENSMUSP00000075513|ensembl:ENSMUSP00000079727|ensembl:ENSMUSP00000157807|uniprotkb:Q99KT7|uniprotkb:Q9DCY7	psi-mi:p97493-pro_0000034151(display_long)|uniprotkb:Thioredoxin-2(gene name synonym)|uniprotkb:Txn2(gene name)|psi-mi:Txn2(display_short)	psi-mi:enoa_mouse(display_long)|uniprotkb:Eno1(gene name)|psi-mi:Eno1(display_short)|uniprotkb:Eno-1(gene name synonym)|uniprotkb:2-phospho-D-glycerate hydro-lyase(gene name synonym)|uniprotkb:Non-neural enolase(gene name synonym)|uniprotkb:Enolase 1(gene name synonym)	psi-mi:"MI:0096"(pull down)	Chasapis et al. (2019)	pubmed:31018154|imex:IM-28571	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26499412|imex:IM-28571-21	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	intact:EBI-8354432(chain-parent)	ensembl:ENSMUSG00000059040(gene)|ensembl:ENSMUSG00000063524(gene)|ensembl:ENSMUST00000076155(transcript)|ensembl:ENSMUST00000080926(transcript)|ensembl:ENSMUST00000235307(transcript)|go:"GO:0000015"(phosphopyruvate hydratase complex)|go:"GO:0000287"(magnesium ion binding)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0003723"(RNA binding)|go:"GO:0004634"(phosphopyruvate hydratase activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006096"(glycolytic process)|go:"GO:0009986"(cell surface)|go:"GO:0016020"(membrane)|go:"GO:0019897"(extrinsic component of plasma membrane)|go:"GO:0019899"(enzyme binding)|go:"GO:0030426"(growth cone)|go:"GO:0032889"(regulation of vacuole fusion, non-autophagic)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043005"(neuron projection)|go:"GO:0043209"(myelin sheath)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045121"(membrane raft)|go:"GO:0051020"(GTPase binding)|go:"GO:0031072"(heat shock protein binding)|go:"GO:0051099"(positive regulation of binding)|go:"GO:0061621"(canonical glycolysis)|go:"GO:0097060"(synaptic membrane)|go:"GO:0098761"(cellular response to interleukin-7)|go:"GO:0099738"(cell cortex region)|interpro:IPR000941(Enolase)|interpro:IPR020809|interpro:IPR020810|interpro:IPR020811|interpro:IPR029017|interpro:IPR036849|mint:P17182|reactome:R-MMU-70171|reactome:R-MMU-70263|refseq:NP_001020559.1|refseq:NP_075608.2|refseq:XP_006538588.2	-	chain-seq-start:60|chain-seq-end:166	-	figure legend:ST1.1|comment:acid-eluted fraction|dataset:Rare diseases - Interactions investigated in the context of Rare genetic disease|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2020/12/04	2020/12/21	rogid:mvYK6+YgIN/WuGLBCWqsqPLfDyQ10090	rogid:YFpn/7GDB6vXgCYLSxvNns7FlT410090	rigid:Y12P/8lD0zKvIbifDxV5fTMn1mU	false	mutation:34-34	-	-	-	psi-mi:"MI:0082"(peptide massfingerprinting)	psi-mi:"MI:0082"(peptide massfingerprinting)
uniprotkb:P97493-PRO_0000034151	uniprotkb:P61164	intact:EBI-26567598	intact:EBI-774242|uniprotkb:P42024|uniprotkb:Q3TJF9|ensembl:ENSMUSP00000039844	psi-mi:p97493-pro_0000034151(display_long)|uniprotkb:Thioredoxin-2(gene name synonym)|uniprotkb:Txn2(gene name)|psi-mi:Txn2(display_short)	psi-mi:actz_mouse(display_long)|uniprotkb:Centrosome-associated actin homolog(gene name synonym)|uniprotkb:Actin-RPV(gene name synonym)|uniprotkb:ARP1(gene name synonym)|uniprotkb:Actr1a(gene name)|psi-mi:Actr1a(display_short)|uniprotkb:Ctrn1(gene name synonym)	psi-mi:"MI:0096"(pull down)	Chasapis et al. (2019)	pubmed:31018154|imex:IM-28571	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26499412|imex:IM-28571-21	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	intact:EBI-8354432(chain-parent)	refseq:NP_058556.1|ensembl:ENSMUSG00000025228(gene)|ensembl:ENSMUST00000040270(transcript)|go:"GO:0002177"(manchette)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005814"(centriole)|go:"GO:0007283"(spermatogenesis)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0030137"(COPI-coated vesicle)|go:"GO:0043209"(myelin sheath)|go:"GO:0099738"(cell cortex region)|interpro:IPR004000(Actin/actin-like)|interpro:IPR004001(Actin, conserved site)|interpro:IPR020902|interpro:IPR043129|mint:P61164|reactome:R-MMU-2132295|reactome:R-MMU-2565942|reactome:R-MMU-3371497|reactome:R-MMU-380259|reactome:R-MMU-380270|reactome:R-MMU-380284|reactome:R-MMU-380320|reactome:R-MMU-5620912|reactome:R-MMU-6807878|reactome:R-MMU-6811436|reactome:R-MMU-8854518	-	chain-seq-start:60|chain-seq-end:166	-	figure legend:ST1.1|comment:acid-eluted fraction|dataset:Rare diseases - Interactions investigated in the context of Rare genetic disease|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2020/12/04	2020/12/21	rogid:mvYK6+YgIN/WuGLBCWqsqPLfDyQ10090	rogid:aJHKOSj1qmZ7Pk8aZAyWWd8DEdw10090	rigid:Y12P/8lD0zKvIbifDxV5fTMn1mU	false	mutation:34-34	-	-	-	psi-mi:"MI:0082"(peptide massfingerprinting)	psi-mi:"MI:0082"(peptide massfingerprinting)
uniprotkb:P97493-PRO_0000034151	uniprotkb:P23927	intact:EBI-26567598	intact:EBI-299046|ensembl:ENSMUSP00000034562|ensembl:ENSMUSP00000149759|ensembl:ENSMUSP00000149803|ensembl:ENSMUSP00000150669|uniprotkb:Q64325	psi-mi:p97493-pro_0000034151(display_long)|uniprotkb:Thioredoxin-2(gene name synonym)|uniprotkb:Txn2(gene name)|psi-mi:Txn2(display_short)	psi-mi:cryab_mouse(display_long)|uniprotkb:Cryab(gene name)|psi-mi:Cryab(display_short)|uniprotkb:Crya2(gene name synonym)|uniprotkb:"Alpha(B)-crystallin"(gene name synonym)|uniprotkb:P23(gene name synonym)	psi-mi:"MI:0096"(pull down)	Chasapis et al. (2019)	pubmed:31018154|imex:IM-28571	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26499412|imex:IM-28571-21	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	intact:EBI-8354432(chain-parent)	ensembl:ENSMUSG00000032060(gene)|ensembl:ENSMUST00000034562(transcript)|ensembl:ENSMUST00000214962(transcript)|ensembl:ENSMUST00000216755(transcript)|ensembl:ENSMUST00000217475(transcript)|go:"GO:0001540"(amyloid-beta binding)|go:"GO:0001666"(response to hypoxia)|go:"GO:0002088"(lens development in camera-type eye)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005212"(structural constituent of eye lens)|go:"GO:0005576"(extracellular region)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006457"(protein folding)|go:"GO:0007021"(tubulin complex assembly)|go:"GO:0007517"(muscle organ development)|go:"GO:0008017"(microtubule binding)|go:"GO:0008092"(cytoskeletal protein binding)|go:"GO:0009986"(cell surface)|go:"GO:0010259"(multicellular organism aging)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0010941"(regulation of cell death)|go:"GO:0014069"(postsynaptic density)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0030018"(Z disc)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0030424"(axon)|go:"GO:0031109"(microtubule polymerization or depolymerization)|go:"GO:0031333"(negative regulation of protein-containing complex assembly)|go:"GO:0031430"(M band)|go:"GO:0031674"(I band)|go:"GO:0032355"(response to estradiol)|go:"GO:0032387"(negative regulation of intracellular transport)|go:"GO:0032432"(actin filament bundle)|go:"GO:0032991"(protein-containing complex)|go:"GO:0042542"(response to hydrogen peroxide)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043010"(camera-type eye development)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043154"(negative regulation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0043197"(dendritic spine)|go:"GO:0043204"(perikaryon)|go:"GO:0043209"(myelin sheath)|go:"GO:0043292"(contractile fiber)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045202"(synapse)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0046872"(metal ion binding)|go:"GO:0050821"(protein stabilization)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0051403"(stress-activated MAPK cascade)|go:"GO:0060561"(apoptotic process involved in morphogenesis)|go:"GO:0071480"(cellular response to gamma radiation)|go:"GO:0097060"(synaptic membrane)|go:"GO:0097512"(cardiac myofibril)|go:"GO:1905907"(negative regulation of amyloid fibril formation)|go:"GO:2000378"(negative regulation of reactive oxygen species metabolic process)|interpro:IPR001436(Alpha crystallin/Heat shock protein)|interpro:IPR002068(Heat shock protein Hsp20)|interpro:IPR003090(Alpha-crystallin, N-terminal)|interpro:IPR008978(HSP20-like chaperone)|interpro:IPR037882|mint:P23927|reactome:R-MMU-3371571|refseq:XP_006510033.1|refseq:NP_034094.1|refseq:NP_001276711.1|refseq:NP_001276713.1|refseq:NP_001276714.1|dip:DIP-31060N	-	chain-seq-start:60|chain-seq-end:166	-	figure legend:ST1.1|comment:acid-eluted fraction|dataset:Rare diseases - Interactions investigated in the context of Rare genetic disease|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2020/12/04	2020/12/21	rogid:mvYK6+YgIN/WuGLBCWqsqPLfDyQ10090	rogid:LOp5smbeRceV8/P+Eaoh7p+24Vw10090	rigid:Y12P/8lD0zKvIbifDxV5fTMn1mU	false	mutation:34-34	-	-	-	psi-mi:"MI:0082"(peptide massfingerprinting)	psi-mi:"MI:0082"(peptide massfingerprinting)
uniprotkb:P97493-PRO_0000034151	uniprotkb:P62259	intact:EBI-26567598	intact:EBI-356480|uniprotkb:P29360|uniprotkb:P42655|uniprotkb:Q63631|ensembl:ENSMUSP00000070993	psi-mi:p97493-pro_0000034151(display_long)|uniprotkb:Thioredoxin-2(gene name synonym)|uniprotkb:Txn2(gene name)|psi-mi:Txn2(display_short)	psi-mi:1433e_mouse(display_long)|uniprotkb:Ywhae(gene name)|psi-mi:Ywhae(display_short)	psi-mi:"MI:0096"(pull down)	Chasapis et al. (2019)	pubmed:31018154|imex:IM-28571	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26499412|imex:IM-28571-21	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	intact:EBI-8354432(chain-parent)	ensembl:ENSMUSG00000020849(gene)|ensembl:ENSMUST00000067664(transcript)|go:"GO:0000165"(MAPK cascade)|go:"GO:0001764"(neuron migration)|go:"GO:0005246"(calcium channel regulator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0005871"(kinesin complex)|go:"GO:0006605"(protein targeting)|go:"GO:0015459"(potassium channel regulator activity)|go:"GO:0019899"(enzyme binding)|go:"GO:0019903"(protein phosphatase binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0021766"(hippocampus development)|go:"GO:0021987"(cerebral cortex development)|go:"GO:0030424"(axon)|refseq:NP_033562.3|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0034504"(protein localization to nucleus)|go:"GO:0034605"(cellular response to heat)|go:"GO:0035308"(negative regulation of protein dephosphorylation)|go:"GO:0042470"(melanosome)|go:"GO:0042802"(identical protein binding)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045202"(synapse)|go:"GO:0046827"(positive regulation of protein export from nucleus)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0050815"(phosphoserine residue binding)|go:"GO:0051219"(phosphoprotein binding)|go:"GO:0051480"(regulation of cytosolic calcium ion concentration)|go:"GO:0060306"(regulation of membrane repolarization)|go:"GO:0090724"(central region of growth cone)|go:"GO:0097110"(scaffold protein binding)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099072"(regulation of postsynaptic membrane neurotransmitter receptor levels)|go:"GO:1901016"(regulation of potassium ion transmembrane transporter activity)|go:"GO:1901020"(negative regulation of calcium ion transmembrane transporter activity)|go:"GO:1902309"(negative regulation of peptidyl-serine dephosphorylation)|go:"GO:1905913"(negative regulation of calcium ion export across plasma membrane)|interpro:IPR000308(14-3-3 protein)|interpro:IPR023409|interpro:IPR023410|interpro:IPR036815|mint:P62259|reactome:R-MMU-111447|reactome:R-MMU-2028269|reactome:R-MMU-205025|reactome:R-MMU-2565942|reactome:R-MMU-3371453|reactome:R-MMU-3371511|reactome:R-MMU-380259|reactome:R-MMU-380270|reactome:R-MMU-380284|reactome:R-MMU-380320|reactome:R-MMU-5620912|reactome:R-MMU-5625740|reactome:R-MMU-5628897|reactome:R-MMU-75035|reactome:R-MMU-8854518|reactome:R-MMU-8876198	-	chain-seq-start:60|chain-seq-end:166	-	figure legend:ST1.1|comment:acid-eluted fraction|dataset:Rare diseases - Interactions investigated in the context of Rare genetic disease|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2020/12/04	2020/12/21	rogid:mvYK6+YgIN/WuGLBCWqsqPLfDyQ10090	rogid:mnuAjdnQZbMFojll2PnV3xFklXQ10090	rigid:Y12P/8lD0zKvIbifDxV5fTMn1mU	false	mutation:34-34	-	-	-	psi-mi:"MI:0082"(peptide massfingerprinting)	psi-mi:"MI:0082"(peptide massfingerprinting)
uniprotkb:P97493-PRO_0000034151	uniprotkb:P47738	intact:EBI-26567598	intact:EBI-2308120|ensembl:ENSMUSP00000031411	psi-mi:p97493-pro_0000034151(display_long)|uniprotkb:Thioredoxin-2(gene name synonym)|uniprotkb:Txn2(gene name)|psi-mi:Txn2(display_short)	psi-mi:aldh2_mouse(display_long)|uniprotkb:Aldh2(gene name)|psi-mi:Aldh2(display_short)|uniprotkb:Ahd-1(gene name synonym)|uniprotkb:Ahd1(gene name synonym)|uniprotkb:ALDH class 2(gene name synonym)|uniprotkb:AHD-M1(gene name synonym)|uniprotkb:ALDHI(gene name synonym)|uniprotkb:ALDH-E2(gene name synonym)	psi-mi:"MI:0096"(pull down)	Chasapis et al. (2019)	pubmed:31018154|imex:IM-28571	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26499412|imex:IM-28571-21	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	intact:EBI-8354432(chain-parent)	refseq:NP_033786.1|ensembl:ENSMUSG00000029455(gene)|ensembl:ENSMUST00000031411(transcript)|go:"GO:0004029"("aldehyde dehydrogenase (NAD+) activity")|go:"GO:0005739"(mitochondrion)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0006068"(ethanol catabolic process)|go:"GO:0006117"(acetaldehyde metabolic process)|go:"GO:0008631"(intrinsic apoptotic signaling pathway in response to oxidative stress)|go:"GO:0014070"(response to organic cyclic compound)|go:"GO:0042802"(identical protein binding)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043878"("glyceraldehyde-3-phosphate dehydrogenase (NAD+) (non-phosphorylating) activity")|go:"GO:0048149"(behavioral response to ethanol)|go:"GO:0050727"(regulation of inflammatory response)|go:"GO:0051287"(NAD binding)|go:"GO:0070404"(NADH binding)|go:"GO:0110095"(cellular detoxification of aldehyde)|go:"GO:2000377"(regulation of reactive oxygen species metabolic process)|interpro:IPR015590(Aldehyde dehydrogenase)|interpro:IPR016160(Aldehyde dehydrogenase, conserved site)|interpro:IPR016161(Aldehyde/histidinol dehydrogenase)|interpro:IPR016162(Aldehyde dehydrogenase, N-terminal)|interpro:IPR016163(Aldehyde dehydrogenase, C-terminal)|interpro:IPR029510|mint:P47738|reactome:R-MMU-380612|reactome:R-MMU-71384	-	chain-seq-start:60|chain-seq-end:166	-	figure legend:ST1.1|comment:acid-eluted fraction|dataset:Rare diseases - Interactions investigated in the context of Rare genetic disease|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2020/12/04	2020/12/21	rogid:mvYK6+YgIN/WuGLBCWqsqPLfDyQ10090	rogid:C4L2qigIlQeaZH4RsNocJovkPMw10090	rigid:Y12P/8lD0zKvIbifDxV5fTMn1mU	false	mutation:34-34	-	-	-	psi-mi:"MI:0082"(peptide massfingerprinting)	psi-mi:"MI:0082"(peptide massfingerprinting)
uniprotkb:P97493-PRO_0000034151	uniprotkb:P20152	intact:EBI-26567598	intact:EBI-299269|ensembl:ENSMUSP00000028062|uniprotkb:O08704|uniprotkb:Q8CCH1	psi-mi:p97493-pro_0000034151(display_long)|uniprotkb:Thioredoxin-2(gene name synonym)|uniprotkb:Txn2(gene name)|psi-mi:Txn2(display_short)	psi-mi:vime_mouse(display_long)|uniprotkb:Vim(gene name)|psi-mi:Vim(display_short)	psi-mi:"MI:0096"(pull down)	Chasapis et al. (2019)	pubmed:31018154|imex:IM-28571	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26499412|imex:IM-28571-21	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	intact:EBI-8354432(chain-parent)	ensembl:ENSMUSG00000026728(gene)|ensembl:ENSMUST00000028062(transcript)|go:"GO:0003725"(double-stranded RNA binding)|go:"GO:0005200"(structural constituent of cytoskeleton)|go:"GO:0005212"(structural constituent of eye lens)|go:"GO:0005737"(cytoplasm)|go:"GO:0005777"(peroxisome)|go:"GO:0005829"(cytosol)|go:"GO:0005844"(polysome)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005882"(intermediate filament)|go:"GO:0005886"(plasma membrane)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010977"(negative regulation of neuron projection development)|go:"GO:0014002"(astrocyte development)|go:"GO:0016363"(nuclear matrix)|go:"GO:0045109"(intermediate filament organization)|go:"GO:0045111"(intermediate filament cytoskeleton)|go:"GO:0045335"(phagocytic vesicle)|go:"GO:0045727"(positive regulation of translation)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0050770"(regulation of axonogenesis)|go:"GO:0051721"(protein phosphatase 2A binding)|go:"GO:0019900"(kinase binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0060020"(Bergmann glial cell differentiation)|go:"GO:0060252"(positive regulation of glial cell proliferation)|go:"GO:0060395"(SMAD protein signal transduction)|go:"GO:0070307"(lens fiber cell development)|go:"GO:0071222"(cellular response to lipopolysaccharide)|go:"GO:0071225"(cellular response to muramyl dipeptide)|go:"GO:0071346"(cellular response to interferon-gamma)|go:"GO:0097110"(scaffold protein binding)|go:"GO:1900147"(regulation of Schwann cell migration)|go:"GO:1990254"(keratin filament binding)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR006821(Intermediate filament, DNA-binding region)|interpro:IPR018039|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030424"(axon)|go:"GO:0031252"(cell leading edge)|interpro:IPR027699|interpro:IPR039008|mint:P20152|reactome:R-MMU-264870|reactome:R-MMU-390522|reactome:R-MMU-9013422|go:"GO:0032967"(positive regulation of collagen biosynthetic process)|reactome:R-MMU-9646399|go:"GO:0042802"(identical protein binding)|go:"GO:0042995"(cell projection)|go:"GO:0043005"(neuron projection)|go:"GO:0043488"(regulation of mRNA stability)|go:"GO:0044297"(cell body)|go:"GO:0045098"(type III intermediate filament)|go:"GO:0045103"(intermediate filament-based process)|refseq:NP_035831.2|dip:DIP-188N	-	chain-seq-start:60|chain-seq-end:166	-	figure legend:ST1.1|comment:acid-eluted fraction|dataset:Rare diseases - Interactions investigated in the context of Rare genetic disease|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2020/12/04	2020/12/21	rogid:mvYK6+YgIN/WuGLBCWqsqPLfDyQ10090	rogid://GDvGAXOR4hUXNtVpnZefex5v410090	rigid:Y12P/8lD0zKvIbifDxV5fTMn1mU	false	mutation:34-34	-	-	-	psi-mi:"MI:0082"(peptide massfingerprinting)	psi-mi:"MI:0082"(peptide massfingerprinting)
uniprotkb:P97493-PRO_0000034151	uniprotkb:P50516	intact:EBI-26567598	intact:EBI-769977|uniprotkb:Q3TKS0|uniprotkb:Q3U5W3|uniprotkb:Q3U777|uniprotkb:Q3UDZ9|uniprotkb:Q3US31|uniprotkb:Q8CHX2|ensembl:ENSMUSP00000066886|ensembl:ENSMUSP00000110314	psi-mi:p97493-pro_0000034151(display_long)|uniprotkb:Thioredoxin-2(gene name synonym)|uniprotkb:Txn2(gene name)|psi-mi:Txn2(display_short)	psi-mi:vata_mouse(display_long)|uniprotkb:Vacuolar proton pump subunit alpha(gene name synonym)|uniprotkb:V-ATPase 69 kDa subunit(gene name synonym)|uniprotkb:Atp6v1a(gene name)|psi-mi:Atp6v1a(display_short)|uniprotkb:Atp6a1(gene name synonym)|uniprotkb:Atp6a2(gene name synonym)|uniprotkb:Atp6v1a1(gene name synonym)	psi-mi:"MI:0096"(pull down)	Chasapis et al. (2019)	pubmed:31018154|imex:IM-28571	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26499412|imex:IM-28571-21	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	intact:EBI-8354432(chain-parent)	refseq:NP_031534.2|refseq:XP_011244111.1|refseq:XP_006521783.1|refseq:XP_006521784.1|ensembl:ENSMUSG00000052459(gene)|ensembl:ENSMUST00000063661(transcript)|ensembl:ENSMUST00000114666(transcript)|go:"GO:0000221"(vacuolar proton-transporting V-type ATPase, V1 domain)|go:"GO:0005524"(ATP binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005902"(microvillus)|go:"GO:0006879"(cellular iron ion homeostasis)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0030133"(transport vesicle)|go:"GO:0030141"(secretory granule)|go:"GO:0036295"(cellular response to increased oxygen levels)|go:"GO:0043209"(myelin sheath)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0046933"(proton-transporting ATP synthase activity, rotational mechanism)|go:"GO:0046961"(proton-transporting ATPase activity, rotational mechanism)|go:"GO:1902600"(proton transmembrane transport)|interpro:IPR000194(ATPase, F1/V1/A1 complex, alpha/beta subunit, nucleotide-binding)|interpro:IPR004100(ATPase, F1/V1/A1 complex, alpha/beta subunit, N-terminal)|interpro:IPR005725(ATPase, V1 complex, subunit A)|interpro:IPR020003|interpro:IPR022878|interpro:IPR023366|interpro:IPR024034|interpro:IPR027417|interpro:IPR031686|interpro:IPR036121|mint:P50516|reactome:R-MMU-1222556|reactome:R-MMU-77387|reactome:R-MMU-917977|reactome:R-MMU-9639288|reactome:R-MMU-983712	-	chain-seq-start:60|chain-seq-end:166	-	figure legend:ST1.1|comment:acid-eluted fraction|dataset:Rare diseases - Interactions investigated in the context of Rare genetic disease|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2020/12/04	2020/12/21	rogid:mvYK6+YgIN/WuGLBCWqsqPLfDyQ10090	rogid:E6xeAhJA1x3386eC6JZXXKgRU0Q10090	rigid:Y12P/8lD0zKvIbifDxV5fTMn1mU	false	mutation:34-34	-	-	-	psi-mi:"MI:0082"(peptide massfingerprinting)	psi-mi:"MI:0082"(peptide massfingerprinting)
uniprotkb:P97493-PRO_0000034151	uniprotkb:Q9DB77	intact:EBI-26567598	intact:EBI-773760|uniprotkb:Q8BK11|uniprotkb:Q9CVK7|ensembl:ENSMUSP00000033176	psi-mi:p97493-pro_0000034151(display_long)|uniprotkb:Thioredoxin-2(gene name synonym)|uniprotkb:Txn2(gene name)|psi-mi:Txn2(display_short)	psi-mi:qcr2_mouse(display_long)|uniprotkb:Ubiquinol-cytochrome-c reductase complex core protein 2(gene name synonym)|uniprotkb:Core protein II(gene name synonym)|uniprotkb:Complex III subunit 2(gene name synonym)|uniprotkb:Uqcrc2(gene name)|psi-mi:Uqcrc2(display_short)	psi-mi:"MI:0096"(pull down)	Chasapis et al. (2019)	pubmed:31018154|imex:IM-28571	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26499412|imex:IM-28571-21	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	intact:EBI-8354432(chain-parent)	refseq:NP_080175.1|ensembl:ENSMUSG00000030884(gene)|ensembl:ENSMUST00000033176(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005750"(mitochondrial respiratory chain complex III)|go:"GO:0005751"(mitochondrial respiratory chain complex IV)|go:"GO:0006508"(proteolysis)|go:"GO:0042493"|go:"GO:0043209"(myelin sheath)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0046872"(metal ion binding)|interpro:IPR001431(Peptidase M16, zinc-binding site)|interpro:IPR007863(Peptidase M16, C-terminal)|interpro:IPR011249(Metalloenzyme, LuxS/M16 peptidase-like, metal-binding)|interpro:IPR011765(Peptidase M16, N-terminal)|mint:Q9DB77|reactome:R-MMU-611105	-	chain-seq-start:60|chain-seq-end:166	-	figure legend:ST1.1|comment:acid-eluted fraction|dataset:Rare diseases - Interactions investigated in the context of Rare genetic disease|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2020/12/04	2020/12/21	rogid:mvYK6+YgIN/WuGLBCWqsqPLfDyQ10090	rogid:CTpkPoAK0EWa6sxA5LJY0srVn/s10090	rigid:Y12P/8lD0zKvIbifDxV5fTMn1mU	false	mutation:34-34	-	-	-	psi-mi:"MI:0082"(peptide massfingerprinting)	psi-mi:"MI:0082"(peptide massfingerprinting)
uniprotkb:P97493-PRO_0000034151	uniprotkb:Q7TMM9	intact:EBI-26567598	intact:EBI-2255578|ensembl:ENSMUSP00000060246	psi-mi:p97493-pro_0000034151(display_long)|uniprotkb:Thioredoxin-2(gene name synonym)|uniprotkb:Txn2(gene name)|psi-mi:Txn2(display_short)	psi-mi:tbb2a_mouse(display_long)|uniprotkb:Tubb2(gene name synonym)|uniprotkb:Tubb2a(gene name)|psi-mi:Tubb2a(display_short)	psi-mi:"MI:0096"(pull down)	Chasapis et al. (2019)	pubmed:31018154|imex:IM-28571	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26499412|imex:IM-28571-21	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	intact:EBI-8354432(chain-parent)	refseq:NP_033476.1|ensembl:ENSMUSG00000058672(gene)|ensembl:ENSMUST00000056427(transcript)|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0001764"(neuron migration)|go:"GO:0005200"(structural constituent of cytoskeleton)|go:"GO:0005525"(GTP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005874"(microtubule)|interpro:IPR000217(Tubulin)|interpro:IPR002453(Beta tubulin)|interpro:IPR003008(Tubulin/FtsZ, GTPase)|interpro:IPR008280(Tubulin/FtsZ, C-terminal)|interpro:IPR013838(Beta tubulin, autoregulation binding site)|interpro:IPR017975|interpro:IPR018316|interpro:IPR023123|interpro:IPR036525|interpro:IPR037103|mint:Q7TMM9|reactome:R-MMU-190840|reactome:R-MMU-2132295|reactome:R-MMU-2467813|reactome:R-MMU-2500257|reactome:R-MMU-3371497|reactome:R-MMU-380320|reactome:R-MMU-437239|reactome:R-MMU-5610787|reactome:R-MMU-5617833|reactome:R-MMU-5620924|reactome:R-MMU-5626467|reactome:R-MMU-5663220|reactome:R-MMU-6807878|reactome:R-MMU-6811434|reactome:R-MMU-6811436|reactome:R-MMU-68877|reactome:R-MMU-8852276|reactome:R-MMU-8955332|reactome:R-MMU-9646399|reactome:R-MMU-9648025|reactome:R-MMU-9668328|reactome:R-MMU-983189	-	chain-seq-start:60|chain-seq-end:166	-	figure legend:ST1.1|comment:acid-eluted fraction|dataset:Rare diseases - Interactions investigated in the context of Rare genetic disease|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2020/12/04	2020/12/21	rogid:mvYK6+YgIN/WuGLBCWqsqPLfDyQ10090	rogid:XN9uTGU0KxQjMod0AGnM+XJoHyk10090	rigid:Y12P/8lD0zKvIbifDxV5fTMn1mU	false	mutation:34-34	-	-	-	psi-mi:"MI:0082"(peptide massfingerprinting)	psi-mi:"MI:0082"(peptide massfingerprinting)
uniprotkb:P97493-PRO_0000034151	uniprotkb:P07724	intact:EBI-26567598	intact:EBI-1183810|uniprotkb:Q3TV03|uniprotkb:Q61802|uniprotkb:Q8C7C7|uniprotkb:Q8C7H3|uniprotkb:Q8CG74|ensembl:ENSMUSP00000031314	psi-mi:p97493-pro_0000034151(display_long)|uniprotkb:Thioredoxin-2(gene name synonym)|uniprotkb:Txn2(gene name)|psi-mi:Txn2(display_short)	psi-mi:albu_mouse(display_long)|uniprotkb:Alb(gene name)|psi-mi:Alb(display_short)|uniprotkb:Alb1(gene name synonym)|uniprotkb:Alb-1(gene name synonym)	psi-mi:"MI:0096"(pull down)	Chasapis et al. (2019)	pubmed:31018154|imex:IM-28571	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26499412|imex:IM-28571-21	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	intact:EBI-8354432(chain-parent)	refseq:NP_033784.2|ensembl:ENSMUSG00000029368(gene)|ensembl:ENSMUST00000031314(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0005504"(fatty acid binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005604"(basement membrane)|go:"GO:0005615"(extracellular space)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0008270"(zinc ion binding)|go:"GO:0009267"(cellular response to starvation)|go:"GO:0015643"(toxic substance binding)|go:"GO:0019825"(oxygen binding)|go:"GO:0019899"(enzyme binding)|go:"GO:0030170"(pyridoxal phosphate binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043209"(myelin sheath)|go:"GO:0046010"(positive regulation of circadian sleep/wake cycle, non-REM sleep)|go:"GO:0051087"(chaperone binding)|go:"GO:0051659"(maintenance of mitochondrion location)|go:"GO:0070062"(extracellular exosome)|go:"GO:0072341"(modified amino acid binding)|go:"GO:0140272"(exogenous protein binding)|go:"GO:1903981"(enterobactin binding)|interpro:IPR000264(Serum albumin)|interpro:IPR014760(Serum albumin, N-terminal)|interpro:IPR020857|interpro:IPR020858|interpro:IPR021177|mint:P07724|reactome:R-MMU-114608|reactome:R-MMU-159418|reactome:R-MMU-189451|reactome:R-MMU-189483|reactome:R-MMU-2168880|reactome:R-MMU-381426|reactome:R-MMU-879518|reactome:R-MMU-8957275|reactome:R-MMU-8964058|reactome:R-MMU-9707564	-	chain-seq-start:60|chain-seq-end:166	-	figure legend:ST1.1|comment:acid-eluted fraction|dataset:Rare diseases - Interactions investigated in the context of Rare genetic disease|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2020/12/04	2020/12/21	rogid:mvYK6+YgIN/WuGLBCWqsqPLfDyQ10090	rogid:R7zO/mB332rAl8J+WrXfsHzjSYs10090	rigid:Y12P/8lD0zKvIbifDxV5fTMn1mU	false	mutation:34-34	-	-	-	psi-mi:"MI:0082"(peptide massfingerprinting)	psi-mi:"MI:0082"(peptide massfingerprinting)
uniprotkb:P97493-PRO_0000034151	uniprotkb:O55131	intact:EBI-26567598	intact:EBI-772161	psi-mi:p97493-pro_0000034151(display_long)|uniprotkb:Thioredoxin-2(gene name synonym)|uniprotkb:Txn2(gene name)|psi-mi:Txn2(display_short)	psi-mi:sept7_mouse(display_long)|uniprotkb:Septin7(gene name)|psi-mi:Septin7(display_short)|uniprotkb:CDC10 protein homolog(gene name synonym)|uniprotkb:Cdc10(gene name synonym)|uniprotkb:Sept7(gene name synonym)	psi-mi:"MI:0096"(pull down)	Chasapis et al. (2019)	pubmed:31018154|imex:IM-28571	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26499412|imex:IM-28571-21	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	intact:EBI-8354432(chain-parent)	refseq:NP_001192296.1|interpro:IPR016491(Septin)|interpro:IPR008115(Septin 7)|interpro:IPR030379|interpro:IPR027417|mint:O55131|go:"GO:0000281"(mitotic cytokinesis)|go:"GO:0000776"(kinetochore)|go:"GO:0001725"(stress fiber)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005819"(spindle)|go:"GO:0005930"(axoneme)|go:"GO:0005938"(cell cortex)|go:"GO:0005940"(septin ring)|go:"GO:0007283"(spermatogenesis)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0016020"(membrane)|go:"GO:0016476"(regulation of embryonic cell shape)|go:"GO:0030496"(midbody)|go:"GO:0030865"(cortical cytoskeleton organization)|go:"GO:0031105"(septin complex)|go:"GO:0031270"(pseudopodium retraction)|go:"GO:0032153"(cell division site)|go:"GO:0032154"(cleavage furrow)|go:"GO:0032156"(septin cytoskeleton)|go:"GO:0032160"(septin filament array)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034613"(cellular protein localization)|go:"GO:0042734"(presynaptic membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0043005"(neuron projection)|go:"GO:0043209"(myelin sheath)|go:"GO:0043679"(axon terminus)|go:"GO:0044297"(cell body)|go:"GO:0045202"(synapse)|go:"GO:0048668"(collateral sprouting)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0060271"(cilium assembly)|go:"GO:0060997"(dendritic spine morphogenesis)|go:"GO:0061640"(cytoskeleton-dependent cytokinesis)|go:"GO:0097227"(sperm annulus)|go:"GO:0097730"(non-motile cilium)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099173"(postsynapse organization)|go:"GO:1902857"(positive regulation of non-motile cilium assembly)|reactome:R-MMU-5687128	-	chain-seq-start:60|chain-seq-end:166	-	figure legend:ST1.1|comment:acid-eluted fraction|dataset:Rare diseases - Interactions investigated in the context of Rare genetic disease|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2020/12/04	2020/12/21	rogid:mvYK6+YgIN/WuGLBCWqsqPLfDyQ10090	rogid:VULb4UyoWVn5vRWIzERa9YQJIYo10090	rigid:Y12P/8lD0zKvIbifDxV5fTMn1mU	false	mutation:34-34	-	-	-	psi-mi:"MI:0082"(peptide massfingerprinting)	psi-mi:"MI:0082"(peptide massfingerprinting)
uniprotkb:P97493-PRO_0000034151	uniprotkb:Q8C1B7	intact:EBI-26567598	intact:EBI-772076|uniprotkb:Q3TBA0|uniprotkb:Q3TC24|uniprotkb:Q5D0F0|uniprotkb:Q6P2K5|uniprotkb:Q6P6I0|ensembl:ENSMUSP00000143928	psi-mi:p97493-pro_0000034151(display_long)|uniprotkb:Thioredoxin-2(gene name synonym)|uniprotkb:Txn2(gene name)|psi-mi:Txn2(display_short)	psi-mi:sep11_mouse(display_long)|uniprotkb:Septin11(gene name)|psi-mi:Septin11(display_short)|uniprotkb:D5Ertd606e(gene name synonym)|uniprotkb:Sept11(gene name synonym)	psi-mi:"MI:0096"(pull down)	Chasapis et al. (2019)	pubmed:31018154|imex:IM-28571	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26499412|imex:IM-28571-21	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	intact:EBI-8354432(chain-parent)	refseq:NP_001009818.1|refseq:NP_001297598.1|refseq:NP_001297600.1|ensembl:ENSMUSG00000058013(gene)|ensembl:ENSMUST00000201421(transcript)|go:"GO:0001725"(stress fiber)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005940"(septin ring)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0030424"(axon)|go:"GO:0031105"(septin complex)|go:"GO:0032153"(cell division site)|go:"GO:0034613"(cellular protein localization)|go:"GO:0043197"(dendritic spine)|go:"GO:0050807"(regulation of synapse organization)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0061640"(cytoskeleton-dependent cytokinesis)|go:"GO:0098794"(postsynapse)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0098982"(GABA-ergic synapse)|go:"GO:0099629"(postsynaptic specialization of symmetric synapse)|interpro:IPR016491(Septin)|interpro:IPR027417|interpro:IPR030379|mint:Q8C1B7	-	chain-seq-start:60|chain-seq-end:166	-	figure legend:ST1.1|comment:acid-eluted fraction|dataset:Rare diseases - Interactions investigated in the context of Rare genetic disease|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2020/12/04	2020/12/21	rogid:mvYK6+YgIN/WuGLBCWqsqPLfDyQ10090	rogid:RfdukqyhC/1qeJHPQmrz7ryDmdY10090	rigid:Y12P/8lD0zKvIbifDxV5fTMn1mU	false	mutation:34-34	-	-	-	psi-mi:"MI:0082"(peptide massfingerprinting)	psi-mi:"MI:0082"(peptide massfingerprinting)
uniprotkb:P97493-PRO_0000034151	uniprotkb:Q63836	intact:EBI-26567598	intact:EBI-1371777|uniprotkb:Q8R1T6	psi-mi:p97493-pro_0000034151(display_long)|uniprotkb:Thioredoxin-2(gene name synonym)|uniprotkb:Txn2(gene name)|psi-mi:Txn2(display_short)	psi-mi:sbp2_mouse(display_long)|uniprotkb:Selenbp2(gene name)|psi-mi:Selenbp2(display_short)|uniprotkb:Lpsb2(gene name synonym)|uniprotkb:56 kDa acetaminophen-binding protein(gene name synonym)	psi-mi:"MI:0096"(pull down)	Chasapis et al. (2019)	pubmed:31018154|imex:IM-28571	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26499412|imex:IM-28571-21	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	intact:EBI-8354432(chain-parent)	refseq:NP_062287.1|interpro:IPR008826(Selenium-binding protein)|mint:Q63836|go:"GO:0001650"(fibrillar center)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0008430"(selenium binding)|go:"GO:0015031"(protein transport)|go:"GO:0016020"(membrane)	-	chain-seq-start:60|chain-seq-end:166	-	figure legend:ST1.1|comment:acid-eluted fraction|dataset:Rare diseases - Interactions investigated in the context of Rare genetic disease|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2020/12/04	2020/12/21	rogid:mvYK6+YgIN/WuGLBCWqsqPLfDyQ10090	rogid:E/xxMHifa3vpfQexdSnn7gZN9Ws10090	rigid:Y12P/8lD0zKvIbifDxV5fTMn1mU	false	mutation:34-34	-	-	-	psi-mi:"MI:0082"(peptide massfingerprinting)	psi-mi:"MI:0082"(peptide massfingerprinting)
uniprotkb:P97493-PRO_0000034151	uniprotkb:Q9WTM5	intact:EBI-26567598	intact:EBI-2549911|ensembl:ENSMUSP00000103400|ensembl:ENSMUSP00000147502	psi-mi:p97493-pro_0000034151(display_long)|uniprotkb:Thioredoxin-2(gene name synonym)|uniprotkb:Txn2(gene name)|psi-mi:Txn2(display_short)	psi-mi:ruvb2_mouse(display_long)|uniprotkb:Ruvbl2(gene name)|psi-mi:Ruvbl2(display_short)|uniprotkb:p47 protein(gene name synonym)	psi-mi:"MI:0096"(pull down)	Chasapis et al. (2019)	pubmed:31018154|imex:IM-28571	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26499412|imex:IM-28571-21	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	intact:EBI-8354432(chain-parent)	ensembl:ENSMUSG00000003868(gene)|ensembl:ENSMUST00000107771(transcript)|ensembl:ENSMUST00000211214(transcript)|go:"GO:0000492"(box C/D snoRNP assembly)|go:"GO:0000791"(euchromatin)|go:"GO:0000812"(Swr1 complex)|go:"GO:0034644"(cellular response to UV)|go:"GO:0035066"(positive regulation of histone acetylation)|go:"GO:0035267"(NuA4 histone acetyltransferase complex)|go:"GO:0031490"(chromatin DNA binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043139"(5'-3' DNA helicase activity)|go:"GO:0043531"(ADP binding)|go:"GO:0043967"(histone H4 acetylation)|go:"GO:0043968"(histone H2A acetylation)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0051117"(ATPase binding)|go:"GO:0071169"(establishment of protein localization to chromatin)|go:"GO:0071339"(MLL1 complex)|go:"GO:0071392"(cellular response to estradiol stimulus)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:0097255"(R2TP complex)|go:"GO:0120293"(dynein axonemal particle)|go:"GO:0140585"(promoter-enhancer loop anchoring activity)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000979"(RNA polymerase II core promoter sequence-specific DNA binding)|go:"GO:0001094"(TFIID-class transcription factor complex binding)|go:"GO:0003678"(DNA helicase activity)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0006281"(DNA repair)|go:"GO:0006310"(DNA recombination)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0016573"(histone acetylation)|go:"GO:0017025"(TBP-class protein binding)|go:"GO:0031011"(Ino80 complex)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR010339(TIP49, C-terminal)|interpro:IPR027238|interpro:IPR027417|interpro:IPR037942|interpro:IPR041048|interpro:IPR042487|mint:Q9WTM5|go:"GO:0140603"(obsolete ATP hydrolysis activity)|refseq:NP_035434.1|refseq:XP_006540785.1|refseq:XP_006540786.1	-	chain-seq-start:60|chain-seq-end:166	-	figure legend:ST1.1|comment:acid-eluted fraction|dataset:Rare diseases - Interactions investigated in the context of Rare genetic disease|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2020/12/04	2020/12/21	rogid:mvYK6+YgIN/WuGLBCWqsqPLfDyQ10090	rogid:tHnjngaz5qWy9sPXagFLp3TRDtA10090	rigid:Y12P/8lD0zKvIbifDxV5fTMn1mU	false	mutation:34-34	-	-	-	psi-mi:"MI:0082"(peptide massfingerprinting)	psi-mi:"MI:0082"(peptide massfingerprinting)
uniprotkb:P97493-PRO_0000034151	uniprotkb:P24549	intact:EBI-26567598	intact:EBI-773059|uniprotkb:Q7TQJ0|uniprotkb:Q811J0|ensembl:ENSMUSP00000084918|ensembl:ENSMUSP00000153410	psi-mi:p97493-pro_0000034151(display_long)|uniprotkb:Thioredoxin-2(gene name synonym)|uniprotkb:Txn2(gene name)|psi-mi:Txn2(display_short)	psi-mi:al1a1_mouse(display_long)|uniprotkb:Aldehyde dehydrogenase family 1 member A1(gene name synonym)|uniprotkb:Aldehyde dehydrogenase, cytosolic(gene name synonym)|uniprotkb:ALHDII(gene name synonym)|uniprotkb:ALDH-E1(gene name synonym)|uniprotkb:Aldh1a1(gene name)|psi-mi:Aldh1a1(display_short)|uniprotkb:Ahd2(gene name synonym)|uniprotkb:Ahd-2(gene name synonym)|uniprotkb:Aldh1(gene name synonym)|uniprotkb:3-deoxyglucosone dehydrogenase(gene name synonym)|uniprotkb:Retinal dehydrogenase 1(gene name synonym)	psi-mi:"MI:0096"(pull down)	Chasapis et al. (2019)	pubmed:31018154|imex:IM-28571	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26499412|imex:IM-28571-21	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	intact:EBI-8354432(chain-parent)	refseq:NP_038495.2|ensembl:ENSMUSG00000053279(gene)|ensembl:ENSMUST00000087638(transcript)|ensembl:ENSMUST00000225337(transcript)|go:"GO:0001523"(retinoid metabolic process)|go:"GO:0001758"(retinal dehydrogenase activity)|go:"GO:0002072"(optic cup morphogenesis involved in camera-type eye development)|go:"GO:0002138"(retinoic acid biosynthetic process)|go:"GO:0004028"(3-chloroallyl aldehyde dehydrogenase activity)|go:"GO:0004029"("aldehyde dehydrogenase (NAD+) activity")|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006979"(response to oxidative stress)|go:"GO:0009449"(gamma-aminobutyric acid biosynthetic process)|go:"GO:0018479"("benzaldehyde dehydrogenase (NAD+) activity")|go:"GO:0019145"(aminobutyraldehyde dehydrogenase activity)|go:"GO:0030392"(fructosamine catabolic process)|go:"GO:0030424"(axon)|go:"GO:0036438"(maintenance of lens transparency)|go:"GO:0042493"|go:"GO:0042572"(retinol metabolic process)|go:"GO:0042573"(retinoic acid metabolic process)|go:"GO:0042802"(identical protein binding)|go:"GO:0042904"(9-cis-retinoic acid biosynthetic process)|go:"GO:0042905"(9-cis-retinoic acid metabolic process)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0045202"(synapse)|go:"GO:0045471"(response to ethanol)|go:"GO:0048048"(embryonic eye morphogenesis)|go:"GO:0051287"(NAD binding)|go:"GO:0106373"(3-deoxyglucosone dehydrogenase activity)|go:"GO:0110095"(cellular detoxification of aldehyde)|go:"GO:0120163"(negative regulation of cold-induced thermogenesis)|interpro:IPR015590(Aldehyde dehydrogenase)|interpro:IPR016160(Aldehyde dehydrogenase, conserved site)|interpro:IPR016161(Aldehyde/histidinol dehydrogenase)|interpro:IPR016162(Aldehyde dehydrogenase, N-terminal)|interpro:IPR016163(Aldehyde dehydrogenase, C-terminal)|interpro:IPR029510|mint:P24549|reactome:R-MMU-5365859|reactome:R-MMU-70350|reactome:R-MMU-71384	-	chain-seq-start:60|chain-seq-end:166	-	figure legend:ST1.1|comment:acid-eluted fraction|dataset:Rare diseases - Interactions investigated in the context of Rare genetic disease|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2020/12/04	2020/12/21	rogid:mvYK6+YgIN/WuGLBCWqsqPLfDyQ10090	rogid:Pxq+ceMp26bDX9sVYBlAOpDSrXs10090	rigid:Y12P/8lD0zKvIbifDxV5fTMn1mU	false	mutation:34-34	-	-	-	psi-mi:"MI:0082"(peptide massfingerprinting)	psi-mi:"MI:0082"(peptide massfingerprinting)
uniprotkb:P97493-PRO_0000034151	uniprotkb:P60710	intact:EBI-26567598	intact:EBI-353957|ensembl:ENSMUSP00000098066|uniprotkb:P02570|uniprotkb:P70514|uniprotkb:P99021|uniprotkb:Q11211|uniprotkb:Q3TI89|uniprotkb:Q3TVP6|uniprotkb:Q64316|uniprotkb:Q6ZWM3	psi-mi:p97493-pro_0000034151(display_long)|uniprotkb:Thioredoxin-2(gene name synonym)|uniprotkb:Txn2(gene name)|psi-mi:Txn2(display_short)	psi-mi:actb_mouse(display_long)|uniprotkb:Actb(gene name)|psi-mi:Actb(display_short)|uniprotkb:Beta-actin(gene name synonym)	psi-mi:"MI:0096"(pull down)	Chasapis et al. (2019)	pubmed:31018154|imex:IM-28571	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26499412|imex:IM-28571-21	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	intact:EBI-8354432(chain-parent)	ensembl:ENSMUSG00000029580(gene)|ensembl:ENSMUST00000100497(transcript)|refseq:NP_031419.1|go:"GO:0002102"(podosome)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005884"(actin filament)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005912"(adherens junction)|go:"GO:0005925"(focal adhesion)|go:"GO:0007163"(establishment or maintenance of cell polarity)|go:"GO:0007409"(axonogenesis)|go:"GO:0014069"(postsynaptic density)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0016020"(membrane)|go:"GO:0019894"(kinesin binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0022898"(regulation of transmembrane transporter activity)|go:"GO:0030027"(lamellipodium)|go:"GO:0030424"(axon)|go:"GO:0030863"(cortical cytoskeleton)|go:"GO:0030957"(Tat protein binding)|go:"GO:0032091"(negative regulation of protein binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034333"(adherens junction assembly)|go:"GO:0035267"(NuA4 histone acetyltransferase complex)|go:"GO:0036464"(cytoplasmic ribonucleoprotein granule)|go:"GO:0071257"(cellular response to electrical stimulus)|go:"GO:0071896"(protein localization to adherens junction)|go:"GO:0072749"(cellular response to cytochalasin B)|go:"GO:0097433"(dense body)|go:"GO:0098685"(Schaffer collateral - CA1 synapse)|go:"GO:0098871"(postsynaptic actin cytoskeleton)|go:"GO:0098973"(structural constituent of postsynaptic actin cytoskeleton)|go:"GO:0098974"(postsynaptic actin cytoskeleton organization)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0150111"(regulation of transepithelial transport)|go:"GO:1903076"(regulation of protein localization to plasma membrane)|go:"GO:1904030"(negative regulation of cyclin-dependent protein kinase activity)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR004000(Actin/actin-like)|interpro:IPR004001(Actin, conserved site)|interpro:IPR020902|interpro:IPR043129|mint:P60710|reactome:R-MMU-190873|reactome:R-MMU-196025|reactome:R-MMU-2029482|reactome:R-MMU-3928662|reactome:R-MMU-418990|reactome:R-MMU-437239|reactome:R-MMU-4420097|reactome:R-MMU-445095|reactome:R-MMU-446353|reactome:R-MMU-5250924|reactome:R-MMU-5626467|reactome:R-MMU-5663213|reactome:R-MMU-5663220|reactome:R-MMU-5674135|reactome:R-MMU-5689603|reactome:R-MMU-5696394|reactome:R-MMU-8856828|reactome:R-MMU-9035034|go:"GO:0042802"(identical protein binding)|go:"GO:0043209"(myelin sheath)|go:"GO:0043296"(apical junction complex)|go:"GO:0044305"(calyx of Held)|go:"GO:0045121"(membrane raft)|go:"GO:0045176"(apical protein localization)|go:"GO:0045202"(synapse)|go:"GO:0048488"(synaptic vesicle endocytosis)|go:"GO:0048870"(cell motility)|go:"GO:0050998"(nitric-oxide synthase binding)|go:"GO:0051621"(regulation of norepinephrine uptake)|go:"GO:0070160"(tight junction)|go:"GO:0001725"(stress fiber)|go:"GO:0001738"(morphogenesis of a polarized epithelium)|go:"GO:0000079"(regulation of cyclin-dependent protein serine/threonine kinase activity)|dip:DIP-31574N	-	chain-seq-start:60|chain-seq-end:166	-	figure legend:ST1.1|comment:acid-eluted fraction|dataset:Rare diseases - Interactions investigated in the context of Rare genetic disease|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2020/12/04	2020/12/21	rogid:mvYK6+YgIN/WuGLBCWqsqPLfDyQ10090	rogid:Hoge1B8Pn56kvbNTpkSLsQuHwRc10090	rigid:Y12P/8lD0zKvIbifDxV5fTMn1mU	false	mutation:34-34	-	-	-	psi-mi:"MI:0082"(peptide massfingerprinting)	psi-mi:"MI:0082"(peptide massfingerprinting)
uniprotkb:P97493-PRO_0000034151	uniprotkb:Q01730	intact:EBI-26567598	intact:EBI-2906826	psi-mi:p97493-pro_0000034151(display_long)|uniprotkb:Thioredoxin-2(gene name synonym)|uniprotkb:Txn2(gene name)|psi-mi:Txn2(display_short)	psi-mi:rsu1_mouse(display_long)|uniprotkb:Rsu1(gene name)|psi-mi:Rsu1(display_short)|uniprotkb:Rsp1(gene name synonym)	psi-mi:"MI:0096"(pull down)	Chasapis et al. (2019)	pubmed:31018154|imex:IM-28571	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26499412|imex:IM-28571-21	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	intact:EBI-8354432(chain-parent)	go:"GO:0005925"(focal adhesion)|go:"GO:0007165"(signal transduction)|go:"GO:0007265"(Ras protein signal transduction)|go:"GO:0010811"(positive regulation of cell-substrate adhesion)|go:"GO:0043547"(positive regulation of GTPase activity)|go:"GO:2000179"(positive regulation of neural precursor cell proliferation)|reactome:R-MMU-446388|interpro:IPR001611(Leucine-rich repeat)|interpro:IPR003591(Leucine-rich repeat, typical subtype)|interpro:IPR032675|mint:Q01730	-	chain-seq-start:60|chain-seq-end:166	-	figure legend:ST1.1|comment:acid-eluted fraction|dataset:Rare diseases - Interactions investigated in the context of Rare genetic disease|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2020/12/04	2020/12/21	rogid:mvYK6+YgIN/WuGLBCWqsqPLfDyQ10090	rogid:nBkDHN46CHPx+UlaFIsFIwJw/2010090	rigid:Y12P/8lD0zKvIbifDxV5fTMn1mU	false	mutation:34-34	-	-	-	psi-mi:"MI:0082"(peptide massfingerprinting)	psi-mi:"MI:0082"(peptide massfingerprinting)
uniprotkb:P97493-PRO_0000034151	uniprotkb:Q99K51	intact:EBI-26567598	intact:EBI-4284839|uniprotkb:B1AX56|uniprotkb:Q3TUZ5|ensembl:ENSMUSP00000033547|ensembl:ENSMUSP00000109691|ensembl:ENSMUSP00000109693	psi-mi:p97493-pro_0000034151(display_long)|uniprotkb:Thioredoxin-2(gene name synonym)|uniprotkb:Txn2(gene name)|psi-mi:Txn2(display_short)	psi-mi:plst_mouse(display_long)|uniprotkb:Pls3(gene name)|psi-mi:Pls3(display_short)|uniprotkb:T-plastin(gene name synonym)	psi-mi:"MI:0096"(pull down)	Chasapis et al. (2019)	pubmed:31018154|imex:IM-28571	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26499412|imex:IM-28571-21	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	intact:EBI-8354432(chain-parent)	refseq:NP_001159925.1|refseq:NP_001159926.1|refseq:NP_663604.1|ensembl:ENSMUSG00000016382(gene)|ensembl:ENSMUST00000033547(transcript)|interpro:IPR011992(EF-Hand type)|interpro:IPR018247|interpro:IPR036872|interpro:IPR039956|interpro:IPR039959|mint:Q99K51|interpro:IPR002048(Calcium-binding EF-hand)|ensembl:ENSMUST00000114059(transcript)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005884"(actin filament)|go:"GO:0005886"(plasma membrane)|go:"GO:0031594"(neuromuscular junction)|go:"GO:0032420"(stereocilium)|go:"GO:0032432"(actin filament bundle)|ensembl:ENSMUST00000114057(transcript)|go:"GO:0051015"(actin filament binding)|go:"GO:0051017"(actin filament bundle assembly)|go:"GO:0051639"(actin filament network formation)|go:"GO:0060348"(bone development)|go:"GO:0098693"(regulation of synaptic vesicle cycle)|go:"GO:0098699"(structural constituent of presynaptic actin cytoskeleton)|interpro:IPR001589(Actinin-type, actin-binding, conserved site)|interpro:IPR001715(Calponin-like actin-binding)	-	chain-seq-start:60|chain-seq-end:166	-	figure legend:ST1.1|comment:acid-eluted fraction|dataset:Rare diseases - Interactions investigated in the context of Rare genetic disease|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2020/12/04	2020/12/21	rogid:mvYK6+YgIN/WuGLBCWqsqPLfDyQ10090	rogid:OG0fV5yrgxepz7CwEtWLxnYFAjo10090	rigid:Y12P/8lD0zKvIbifDxV5fTMn1mU	false	mutation:34-34	-	-	-	psi-mi:"MI:0082"(peptide massfingerprinting)	psi-mi:"MI:0082"(peptide massfingerprinting)
uniprotkb:P97493-PRO_0000034151	uniprotkb:O08807	intact:EBI-26567598	intact:EBI-494652|uniprotkb:Q3U8E4|uniprotkb:B1AZS7|ensembl:ENSMUSP00000026328	psi-mi:p97493-pro_0000034151(display_long)|uniprotkb:Thioredoxin-2(gene name synonym)|uniprotkb:Txn2(gene name)|psi-mi:Txn2(display_short)	psi-mi:prdx4_mouse(display_long)|uniprotkb:Peroxiredoxin IV(gene name synonym)|uniprotkb:Thioredoxin peroxidase AO372(gene name synonym)|uniprotkb:Thioredoxin-dependent peroxide reductase A0372(gene name synonym)|uniprotkb:Antioxidant enzyme AOE372(gene name synonym)|uniprotkb:Thioredoxin-dependent peroxiredoxin 4(gene name synonym)|uniprotkb:Prdx4(gene name)|psi-mi:Prdx4(display_short)	psi-mi:"MI:0096"(pull down)	Chasapis et al. (2019)	pubmed:31018154|imex:IM-28571	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26499412|imex:IM-28571-21	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	intact:EBI-8354432(chain-parent)	refseq:NP_058044.1|refseq:NP_001300640.1|dip:DIP-34137N|ensembl:ENSMUSG00000025289(gene)|ensembl:ENSMUST00000026328(transcript)|go:"GO:0004601"(peroxidase activity)|go:"GO:0005615"(extracellular space)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005790"(smooth endoplasmic reticulum)|go:"GO:0005829"(cytosol)|go:"GO:0006979"(response to oxidative stress)|go:"GO:0007283"(spermatogenesis)|go:"GO:0008584"(male gonad development)|go:"GO:0018401"(peptidyl-proline hydroxylation to 4-hydroxy-L-proline)|go:"GO:0022417"(protein maturation by protein folding)|go:"GO:0030198"(extracellular matrix organization)|go:"GO:0042802"(identical protein binding)|go:"GO:0045454"(cell redox homeostasis)|go:"GO:0051920"(peroxiredoxin activity)|go:"GO:0072593"(reactive oxygen species metabolic process)|go:"GO:2000255"(negative regulation of male germ cell proliferation)|interpro:IPR000866(Alkyl hydroperoxide reductase/ Thiol specific antioxidant/ Mal allergen)|interpro:IPR013766(Thioredoxin domain)|interpro:IPR019479|interpro:IPR036249|mint:O08807|rcsb pdb:3VWU|rcsb pdb:3VWV|rcsb pdb:3W8J|rcsb pdb:3WGX|reactome:R-MMU-6798695	-	chain-seq-start:60|chain-seq-end:166	-	figure legend:ST1.1|comment:acid-eluted fraction|dataset:Rare diseases - Interactions investigated in the context of Rare genetic disease|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2020/12/04	2020/12/21	rogid:mvYK6+YgIN/WuGLBCWqsqPLfDyQ10090	rogid:86EzEedrO6v5Z2dnSB2fSPaV2hc10090	rigid:Y12P/8lD0zKvIbifDxV5fTMn1mU	false	mutation:34-34	-	-	-	psi-mi:"MI:0082"(peptide massfingerprinting)	psi-mi:"MI:0082"(peptide massfingerprinting)
uniprotkb:P97493-PRO_0000034151	uniprotkb:Q61171	intact:EBI-26567598	intact:EBI-444957|uniprotkb:O88376|uniprotkb:Q60796|uniprotkb:Q9CWJ4|uniprotkb:Q9DB49|ensembl:ENSMUSP00000005292|ensembl:ENSMUSP00000105355|ensembl:ENSMUSP00000105356|ensembl:ENSMUSP00000126451	psi-mi:p97493-pro_0000034151(display_long)|uniprotkb:Thioredoxin-2(gene name synonym)|uniprotkb:Txn2(gene name)|psi-mi:Txn2(display_short)	psi-mi:prdx2_mouse(display_long)|uniprotkb:Thioredoxin-dependent peroxiredoxin 2(gene name synonym)|uniprotkb:Thioredoxin peroxidase 1(gene name synonym)|uniprotkb:Thioredoxin-dependent peroxide reductase 1(gene name synonym)|uniprotkb:Thiol-specific antioxidant protein(gene name synonym)|uniprotkb:Prdx2(gene name)|psi-mi:Prdx2(display_short)|uniprotkb:Tdpx1(gene name synonym)|uniprotkb:Tpx(gene name synonym)	psi-mi:"MI:0096"(pull down)	Chasapis et al. (2019)	pubmed:31018154|imex:IM-28571	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26499412|imex:IM-28571-21	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	intact:EBI-8354432(chain-parent)	refseq:NP_035693.3|go:"GO:0042098"(T cell proliferation)|go:"GO:0042743"(hydrogen peroxide metabolic process)|go:"GO:0042744"(hydrogen peroxide catabolic process)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0043209"(myelin sheath)|go:"GO:0043410"(positive regulation of MAPK cascade)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0045321"(leukocyte activation)|go:"GO:0045454"(cell redox homeostasis)|go:"GO:0045581"(negative regulation of T cell differentiation)|go:"GO:0048538"(thymus development)|go:"GO:0048872"(homeostasis of number of cells)|go:"GO:2001237"(negative regulation of extrinsic apoptotic signaling pathway)|go:"GO:2001240"(negative regulation of extrinsic apoptotic signaling pathway in absence of ligand)|interpro:IPR000866(Alkyl hydroperoxide reductase/ Thiol specific antioxidant/ Mal allergen)|interpro:IPR013766(Thioredoxin domain)|interpro:IPR019479|interpro:IPR024706|interpro:IPR036249|mint:Q61171|reactome:R-MMU-3299685|reactome:R-MMU-5628897|go:"GO:0034599"(cellular response to oxidative stress)|refseq:NP_001304314.1|ensembl:ENSMUSG00000005161(gene)|ensembl:ENSMUST00000005292(transcript)|ensembl:ENSMUST00000109733(transcript)|ensembl:ENSMUST00000109734(transcript)|ensembl:ENSMUST00000164807(transcript)|go:"GO:0002357"(defense response to tumor cell)|go:"GO:0002536"(respiratory burst involved in inflammatory response)|go:"GO:0004601"(peroxidase activity)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0006979"(response to oxidative stress)|go:"GO:0008379"(thioredoxin peroxidase activity)|go:"GO:0008430"(selenium binding)|go:"GO:0010310"(regulation of hydrogen peroxide metabolic process)|go:"GO:0016209"(antioxidant activity)|go:"GO:0019430"(removal of superoxide radicals)|go:"GO:0030194"(positive regulation of blood coagulation)|go:"GO:0031665"(negative regulation of lipopolysaccharide-mediated signaling pathway)|go:"GO:0032088"(negative regulation of NF-kappaB transcription factor activity)|go:"GO:0032496"(response to lipopolysaccharide)	-	chain-seq-start:60|chain-seq-end:166	-	figure legend:ST1.1|comment:acid-eluted fraction|dataset:Rare diseases - Interactions investigated in the context of Rare genetic disease|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2020/12/04	2020/12/21	rogid:mvYK6+YgIN/WuGLBCWqsqPLfDyQ10090	rogid:P1NxwIOnv1n4sNzQWtFjy2znSbA10090	rigid:Y12P/8lD0zKvIbifDxV5fTMn1mU	false	mutation:34-34	-	-	-	psi-mi:"MI:0082"(peptide massfingerprinting)	psi-mi:"MI:0082"(peptide massfingerprinting)
uniprotkb:P97493-PRO_0000034151	uniprotkb:Q9WTI7	intact:EBI-26567598	intact:EBI-777558|ensembl:ENSMUSP00000099563|uniprotkb:Q3TBQ4|uniprotkb:Q3U231|uniprotkb:Q5ND46|uniprotkb:Q5ND48|uniprotkb:Q5ND49|uniprotkb:Q9ERB6|uniprotkb:O08571|uniprotkb:O08834|uniprotkb:Q9QW54	psi-mi:p97493-pro_0000034151(display_long)|uniprotkb:Thioredoxin-2(gene name synonym)|uniprotkb:Txn2(gene name)|psi-mi:Txn2(display_short)	psi-mi:myo1c_mouse(display_long)|uniprotkb:Myosin I beta(gene name synonym)|uniprotkb:Myo1c(gene name)|psi-mi:Myo1c(display_short)	psi-mi:"MI:0096"(pull down)	Chasapis et al. (2019)	pubmed:31018154|imex:IM-28571	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26499412|imex:IM-28571-21	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	intact:EBI-8354432(chain-parent)	ensembl:ENSMUSG00000017774(gene)|ensembl:ENSMUST00000102505(transcript)|go:"GO:0000146"(microfilament motor activity)|go:"GO:0003779"(actin binding)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005543"(phospholipid binding)|go:"GO:0005634"(nucleus)|go:"GO:0005643"(nuclear pore)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005902"(microvillus)|go:"GO:0005903"(brush border)|go:"GO:0006605"(protein targeting)|go:"GO:0006612"(protein targeting to membrane)|go:"GO:0007015"(actin filament organization)|mint:Q9WTI7|rcsb pdb:4R8G|reactome:R-MMU-2029482|reactome:R-MMU-5250924|interpro:IPR036961|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0009925"(basal plasma membrane)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0016020"(membrane)|go:"GO:0016328"(lateral plasma membrane)|go:"GO:0016459"(myosin complex)|go:"GO:0016604"(nuclear body)|go:"GO:0030050"(vesicle transport along actin filament)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0030659"(cytoplasmic vesicle membrane)|go:"GO:0030838"(positive regulation of actin filament polymerization)|go:"GO:0031267"(small GTPase binding)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0031941"(filamentous actin)|go:"GO:0031982"(vesicle)|go:"GO:0032420"(stereocilium)|go:"GO:0032421"(stereocilium bundle)|go:"GO:0032587"(ruffle membrane)|go:"GO:0038089"(positive regulation of cell migration by vascular endothelial growth factor signaling pathway)|go:"GO:0045121"(membrane raft)|go:"GO:0045335"(phagocytic vesicle)|go:"GO:0051015"(actin filament binding)|go:"GO:0051028"(mRNA transport)|go:"GO:0060171"(stereocilium membrane)|go:"GO:0071346"(cellular response to interferon-gamma)|go:"GO:0090314"(positive regulation of protein targeting to membrane)|go:"GO:1900078"(positive regulation of cellular response to insulin stimulus)|go:"GO:1900748"(positive regulation of vascular endothelial growth factor signaling pathway)|go:"GO:2000810"(regulation of bicellular tight junction assembly)|interpro:IPR000048(IQ calmodulin-binding region)|interpro:IPR001609(Myosin head, motor region)|interpro:IPR010926(Myosin tail 2)|interpro:IPR027417|interpro:IPR036072|refseq:NP_001074243.1|refseq:NP_001074244.1|refseq:NP_032685.1|refseq:XP_006532492.1|dip:DIP-35498N	-	chain-seq-start:60|chain-seq-end:166	-	figure legend:ST1.1|comment:acid-eluted fraction|dataset:Rare diseases - Interactions investigated in the context of Rare genetic disease|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2020/12/04	2020/12/21	rogid:mvYK6+YgIN/WuGLBCWqsqPLfDyQ10090	rogid:E25nufEJATQnH9pvQlkmAdEOAd810090	rigid:Y12P/8lD0zKvIbifDxV5fTMn1mU	false	mutation:34-34	-	-	-	psi-mi:"MI:0082"(peptide massfingerprinting)	psi-mi:"MI:0082"(peptide massfingerprinting)
uniprotkb:P97493-PRO_0000034151	uniprotkb:P46735	intact:EBI-26567598	intact:EBI-400887|uniprotkb:P70244|uniprotkb:Q80VD8|ensembl:ENSMUSP00000040447	psi-mi:p97493-pro_0000034151(display_long)|uniprotkb:Thioredoxin-2(gene name synonym)|uniprotkb:Txn2(gene name)|psi-mi:Txn2(display_short)	psi-mi:myo1b_mouse(display_long)|uniprotkb:Myo1b(gene name)|psi-mi:Myo1b(display_short)|uniprotkb:Myosin I alpha(gene name synonym)|uniprotkb:MIH-L(gene name synonym)	psi-mi:"MI:0096"(pull down)	Chasapis et al. (2019)	pubmed:31018154|imex:IM-28571	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26499412|imex:IM-28571-21	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	intact:EBI-8354432(chain-parent)	refseq:NP_034993.2|ensembl:ENSMUSG00000018417(gene)|ensembl:ENSMUST00000046390(transcript)|go:"GO:0000146"(microfilament motor activity)|go:"GO:0003774"(cytoskeletal motor activity)|go:"GO:0003779"(actin binding)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005546"(phosphatidylinositol-4,5-bisphosphate binding)|go:"GO:0005547"(phosphatidylinositol-3,4,5-trisphosphate binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005769"(early endosome)|go:"GO:0005884"(actin filament)|go:"GO:0005886"(plasma membrane)|go:"GO:0005902"(microvillus)|go:"GO:0005903"(brush border)|go:"GO:0006892"(post-Golgi vesicle-mediated transport)|go:"GO:0007015"(actin filament organization)|go:"GO:0010008"(endosome membrane)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0016459"(myosin complex)|go:"GO:0030048"(actin filament-based movement)|go:"GO:0030050"(vesicle transport along actin filament)|go:"GO:0030175"(filopodium)|go:"GO:0031982"(vesicle)|go:"GO:0033572"(transferrin transport)|go:"GO:0045177"(apical part of cell)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051015"(actin filament binding)|go:"GO:0051017"(actin filament bundle assembly)|go:"GO:0071944"(cell periphery)|interpro:IPR000048(IQ calmodulin-binding region)|interpro:IPR001609(Myosin head, motor region)|interpro:IPR010926(Myosin tail 2)|interpro:IPR027417|interpro:IPR036072|interpro:IPR036961|mint:P46735	-	chain-seq-start:60|chain-seq-end:166	-	figure legend:ST1.1|comment:acid-eluted fraction|dataset:Rare diseases - Interactions investigated in the context of Rare genetic disease|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2020/12/04	2020/12/21	rogid:mvYK6+YgIN/WuGLBCWqsqPLfDyQ10090	rogid:GStJH3DUQORwMi1ow0mHcBAf4io10090	rigid:Y12P/8lD0zKvIbifDxV5fTMn1mU	false	mutation:34-34	-	-	-	psi-mi:"MI:0082"(peptide massfingerprinting)	psi-mi:"MI:0082"(peptide massfingerprinting)
uniprotkb:P97493-PRO_0000034151	uniprotkb:Q8VDD5	intact:EBI-26567598	intact:EBI-400906|intact:EBI-777674|uniprotkb:Q3UHT9|uniprotkb:Q3UHU4|uniprotkb:Q6KAN6|uniprotkb:Q811I2|ensembl:ENSMUSP00000016771	psi-mi:p97493-pro_0000034151(display_long)|uniprotkb:Thioredoxin-2(gene name synonym)|uniprotkb:Txn2(gene name)|psi-mi:Txn2(display_short)	psi-mi:myh9_mouse(display_long)|uniprotkb:Myh9(gene name)|psi-mi:Myh9(display_short)|uniprotkb:Myosin heavy chain 9(gene name synonym)|uniprotkb:Myosin heavy chain, non-muscle IIa(gene name synonym)|uniprotkb:Non-muscle myosin heavy chain IIa(gene name synonym)|uniprotkb:Cellular myosin heavy chain, type A(gene name synonym)|uniprotkb:Non-muscle myosin heavy chain A(gene name synonym)	psi-mi:"MI:0096"(pull down)	Chasapis et al. (2019)	pubmed:31018154|imex:IM-28571	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26499412|imex:IM-28571-21	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	intact:EBI-8354432(chain-parent)	refseq:NP_071855.2|ensembl:ENSMUSG00000022443(gene)|ensembl:ENSMUST00000016771(transcript)|go:"GO:0000146"(microfilament motor activity)|go:"GO:0000212"(meiotic spindle organization)|go:"GO:0000904"(cell morphogenesis involved in differentiation)|go:"GO:0001525"(angiogenesis)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0001725"(stress fiber)|go:"GO:0001726"(ruffle)|go:"GO:0001768"(establishment of T cell polarity)|go:"GO:0001772"(immunological synapse)|go:"GO:0001778"(plasma membrane repair)|go:"GO:0001931"(uropod)|go:"GO:0003779"(actin binding)|go:"GO:0005178"(integrin binding)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005819"(spindle)|go:"GO:0005826"(actomyosin contractile ring)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005903"(brush border)|go:"GO:0005912"(adherens junction)|go:"GO:0005938"(cell cortex)|go:"GO:0006509"(membrane protein ectodomain proteolysis)|go:"GO:0006911"(phagocytosis, engulfment)|go:"GO:0007155"(cell adhesion)|go:"GO:0007520"(myoblast fusion)|go:"GO:0008180"(COP9 signalosome)|go:"GO:0008360"(regulation of cell shape)|go:"GO:0009898"(cytoplasmic side of plasma membrane)|go:"GO:0015031"(protein transport)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0016459"(myosin complex)|go:"GO:0016460"(myosin II complex)|go:"GO:0016887"(ATP hydrolysis activity)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030048"(actin filament-based movement)|go:"GO:0030220"(platelet formation)|go:"GO:0030224"(monocyte differentiation)|go:"GO:0030863"(cortical cytoskeleton)|go:"GO:0031032"(actomyosin structure organization)|go:"GO:0031252"(cell leading edge)|go:"GO:0031532"(actin cytoskeleton reorganization)|go:"GO:0031594"(neuromuscular junction)|go:"GO:0032154"(cleavage furrow)|go:"GO:0032418"(lysosome localization)|go:"GO:0032506"(cytokinetic process)|go:"GO:0032796"(uropod organization)|go:"GO:0032991"(protein-containing complex)|go:"GO:0042641"(actomyosin)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043495"(protein-membrane adaptor activity)|go:"GO:0043531"(ADP binding)|go:"GO:0043534"(blood vessel endothelial cell migration)|go:"GO:0045055"(regulated exocytosis)|go:"GO:0051015"(actin filament binding)|go:"GO:0051295"(establishment of meiotic spindle localization)|go:"GO:0060471"(cortical granule exocytosis)|go:"GO:0060473"(cortical granule)|go:"GO:0097513"(myosin II filament)|go:"GO:0098609"(cell-cell adhesion)|go:"GO:1903919"(negative regulation of actin filament severing)|go:"GO:1903923"(positive regulation of protein processing in phagocytic vesicle)|go:"GO:1905684"(regulation of plasma membrane repair)|interpro:IPR000048(IQ calmodulin-binding region)|interpro:IPR001609(Myosin head, motor region)|interpro:IPR002928(Myosin tail)|interpro:IPR004009(Myosin, N-terminal, SH3-like)|interpro:IPR008989(Myosin S1 fragment, N-terminal)|interpro:IPR027417|interpro:IPR036961|mint:Q8VDD5|reactome:R-MMU-2029482|reactome:R-MMU-5627123|dip:DIP-29546N	-	chain-seq-start:60|chain-seq-end:166	caution:This sequence has been withdrawn from Uniprot.|crc64:AAAC0E83A0A4F24A	figure legend:ST1.1|comment:acid-eluted fraction|dataset:Rare diseases - Interactions investigated in the context of Rare genetic disease|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2020/12/04	2020/12/21	rogid:mvYK6+YgIN/WuGLBCWqsqPLfDyQ10090	rogid:qYfcGuWOF9npzsKD3zXTuLeP9iE10090	rigid:Y12P/8lD0zKvIbifDxV5fTMn1mU	false	mutation:34-34	-	-	-	psi-mi:"MI:0082"(peptide massfingerprinting)	psi-mi:"MI:0082"(peptide massfingerprinting)
uniprotkb:P97493-PRO_0000034151	uniprotkb:Q3ULD5	intact:EBI-26567598	intact:EBI-6877475|ensembl:ENSMUSP00000022148|uniprotkb:Q3UPS6	psi-mi:p97493-pro_0000034151(display_long)|uniprotkb:Thioredoxin-2(gene name synonym)|uniprotkb:Txn2(gene name)|psi-mi:Txn2(display_short)	psi-mi:mccb_mouse(display_long)|uniprotkb:Mccc2(gene name)|psi-mi:Mccc2(display_short)|uniprotkb:3-methylcrotonyl-CoA carboxylase 2(gene name synonym)|uniprotkb:3-methylcrotonyl-CoA carboxylase non-biotin-containing subunit(gene name synonym)|uniprotkb:"3-methylcrotonyl-CoA:carbon dioxide ligase subunit beta"(gene name synonym)	psi-mi:"MI:0096"(pull down)	Chasapis et al. (2019)	pubmed:31018154|imex:IM-28571	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26499412|imex:IM-28571-21	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	intact:EBI-8354432(chain-parent)	ensembl:ENSMUSG00000021646(gene)|ensembl:ENSMUST00000022148(transcript)|go:"GO:0004485"(methylcrotonoyl-CoA carboxylase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005739"(mitochondrion)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0006552"(leucine catabolic process)|go:"GO:0015936"(coenzyme A metabolic process)|go:"GO:1905202"(methylcrotonoyl-CoA carboxylase complex)|interpro:IPR011762(Acetyl-coenzyme A carboxyltransferase, N-terminal)|interpro:IPR011763(Acetyl-coenzyme A carboxyltransferase, C-terminal)|interpro:IPR029045|interpro:IPR034733|mint:Q3ULD5|reactome:R-MMU-196780|reactome:R-MMU-70895|refseq:NP_084302.1	-	chain-seq-start:60|chain-seq-end:166	-	figure legend:ST1.1|comment:acid-eluted fraction|dataset:Rare diseases - Interactions investigated in the context of Rare genetic disease|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2020/12/04	2020/12/21	rogid:mvYK6+YgIN/WuGLBCWqsqPLfDyQ10090	rogid:0q4wsAWb+zqTRNjZnCPoNabUrbA10090	rigid:Y12P/8lD0zKvIbifDxV5fTMn1mU	false	mutation:34-34	-	-	-	psi-mi:"MI:0082"(peptide massfingerprinting)	psi-mi:"MI:0082"(peptide massfingerprinting)
uniprotkb:P97493-PRO_0000034151	uniprotkb:P11679	intact:EBI-26567598	intact:EBI-6932294|ensembl:ENSMUSP00000023952|uniprotkb:Q3KQK5|uniprotkb:Q3TGI1|uniprotkb:Q3TJE1|uniprotkb:Q3TKY7|uniprotkb:Q61463|uniprotkb:Q61518|uniprotkb:Q61519	psi-mi:p97493-pro_0000034151(display_long)|uniprotkb:Thioredoxin-2(gene name synonym)|uniprotkb:Txn2(gene name)|psi-mi:Txn2(display_short)	psi-mi:k2c8_mouse(display_long)|uniprotkb:Krt8(gene name)|psi-mi:Krt8(display_short)|uniprotkb:Krt2-8(gene name synonym)|uniprotkb:Cytokeratin endo A(gene name synonym)|uniprotkb:Cytokeratin-8(gene name synonym)|uniprotkb:Keratin-8(gene name synonym)|uniprotkb:Type-II keratin Kb8(gene name synonym)	psi-mi:"MI:0096"(pull down)	Chasapis et al. (2019)	pubmed:31018154|imex:IM-28571	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26499412|imex:IM-28571-21	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	intact:EBI-8354432(chain-parent)	ensembl:ENSMUSG00000049382(gene)|ensembl:ENSMUST00000023952(transcript)|go:"GO:0000904"(cell morphogenesis involved in differentiation)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005882"(intermediate filament)|go:"GO:0005911"(cell-cell junction)|go:"GO:0007275"(multicellular organism development)|go:"GO:0016010"(dystrophin-associated glycoprotein complex)|go:"GO:0016327"(apicolateral plasma membrane)|go:"GO:0016363"(nuclear matrix)|go:"GO:0030018"(Z disc)|go:"GO:0033209"(tumor necrosis factor-mediated signaling pathway)|go:"GO:0042383"(sarcolemma)|go:"GO:0043034"(costamere)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045095"(keratin filament)|go:"GO:0045111"(intermediate filament cytoskeleton)|go:"GO:0045214"(sarcomere organization)|go:"GO:0051599"(response to hydrostatic pressure)|go:"GO:0051707"(response to other organism)|go:"GO:0060706"(cell differentiation involved in embryonic placenta development)|go:"GO:0071944"(cell periphery)|go:"GO:0097110"(scaffold protein binding)|go:"GO:0097191"(extrinsic apoptotic signaling pathway)|go:"GO:0097284"(hepatocyte apoptotic process)|interpro:IPR003054(Type II keratin)|interpro:IPR018039|interpro:IPR032444|interpro:IPR039008|mint:P11679|reactome:R-MMU-6805567|reactome:R-MMU-6809371|refseq:NP_112447.2	-	chain-seq-start:60|chain-seq-end:166	-	figure legend:ST1.1|comment:acid-eluted fraction|dataset:Rare diseases - Interactions investigated in the context of Rare genetic disease|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2020/12/04	2020/12/21	rogid:mvYK6+YgIN/WuGLBCWqsqPLfDyQ10090	rogid:tHROsQDYqSSV1Kjirm2RW+r9j3M10090	rigid:Y12P/8lD0zKvIbifDxV5fTMn1mU	false	mutation:34-34	-	-	-	psi-mi:"MI:0082"(peptide massfingerprinting)	psi-mi:"MI:0082"(peptide massfingerprinting)
uniprotkb:P97493-PRO_0000034151	uniprotkb:P14206	intact:EBI-26567598	intact:EBI-1183792|ensembl:ENSMUSP00000035105|ensembl:ENSMUSP00000148933|uniprotkb:Q58E74|uniprotkb:Q8BHL0|uniprotkb:Q8BNL2|uniprotkb:Q91V31|uniprotkb:Q9CY13	psi-mi:p97493-pro_0000034151(display_long)|uniprotkb:Thioredoxin-2(gene name synonym)|uniprotkb:Txn2(gene name)|psi-mi:Txn2(display_short)	psi-mi:rssa_mouse(display_long)|uniprotkb:Rpsa(gene name)|psi-mi:Rpsa(display_short)|uniprotkb:Lamr1(gene name synonym)|uniprotkb:Laminin receptor 1(gene name synonym)|uniprotkb:37/67 kDa laminin receptor(gene name synonym)|uniprotkb:Laminin-binding protein precursor p40(gene name synonym)|uniprotkb:37 kDa oncofetal antigen(gene name synonym)|uniprotkb:OFA/iLRP(gene name synonym)|uniprotkb:P40-8(gene name synonym)|uniprotkb:37 kDa laminin receptor precursor(gene name synonym)|uniprotkb:67 kDa laminin receptor(gene name synonym)	psi-mi:"MI:0096"(pull down)	Chasapis et al. (2019)	pubmed:31018154|imex:IM-28571	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26499412|imex:IM-28571-21	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	intact:EBI-8354432(chain-parent)	ensembl:ENSMUSG00000032518(gene)|refseq:NP_035159.3|ensembl:ENSMUST00000035105(transcript)|ensembl:ENSMUST00000217317(transcript)|go:"GO:0000028"(ribosomal small subunit assembly)|go:"GO:0002181"(cytoplasmic translation)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005055"(laminin receptor activity)|go:"GO:0005604"(basement membrane)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006412"(translation)|go:"GO:0015935"(small ribosomal subunit)|go:"GO:0016020"(membrane)|go:"GO:0022626"(cytosolic ribosome)|go:"GO:0022627"(cytosolic small ribosomal subunit)|go:"GO:0030855"(epithelial cell differentiation)|go:"GO:0043022"(ribosome binding)|interpro:IPR005707(Ribosomal protein S2, eukaryotic/archaeal)|interpro:IPR018130|interpro:IPR023591|interpro:IPR027498|interpro:IPR027504|interpro:IPR032281|mint:P14206|reactome:R-MMU-156827|go:"GO:0043025"(neuronal cell body)|reactome:R-MMU-1799339|reactome:R-MMU-6791226|reactome:R-MMU-72649|reactome:R-MMU-72689|reactome:R-MMU-72695|reactome:R-MMU-72702|reactome:R-MMU-72706|reactome:R-MMU-975956|reactome:R-MMU-975957|go:"GO:0043236"(laminin binding)|go:"GO:0045202"(synapse)|go:"GO:0062023"(collagen-containing extracellular matrix)|go:"GO:0098609"(cell-cell adhesion)|go:"GO:0098978"(glutamatergic synapse)|interpro:IPR001865(Ribosomal protein S2)|dip:DIP-38089N	-	chain-seq-start:60|chain-seq-end:166	-	figure legend:ST1.1|comment:acid-eluted fraction|dataset:Rare diseases - Interactions investigated in the context of Rare genetic disease|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2020/12/04	2020/12/21	rogid:mvYK6+YgIN/WuGLBCWqsqPLfDyQ10090	rogid:Qf5VO9t+mZnGd/vuxHsQyYBuYSQ10090	rigid:Y12P/8lD0zKvIbifDxV5fTMn1mU	false	mutation:34-34	-	-	-	psi-mi:"MI:0082"(peptide massfingerprinting)	psi-mi:"MI:0082"(peptide massfingerprinting)
uniprotkb:P97493-PRO_0000034151	uniprotkb:P70404	intact:EBI-26567598	intact:EBI-773416|ensembl:ENSMUSP00000056502	psi-mi:p97493-pro_0000034151(display_long)|uniprotkb:Thioredoxin-2(gene name synonym)|uniprotkb:Txn2(gene name)|psi-mi:Txn2(display_short)	psi-mi:idhg1_mouse(display_long)|uniprotkb:Isocitric dehydrogenase subunit gamma(gene name synonym)|uniprotkb:"NAD(+)-specific ICDH subunit gamma"(gene name synonym)|uniprotkb:Idh3g(gene name)|psi-mi:Idh3g(display_short)	psi-mi:"MI:0096"(pull down)	Chasapis et al. (2019)	pubmed:31018154|imex:IM-28571	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26499412|imex:IM-28571-21	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	intact:EBI-8354432(chain-parent)	refseq:NP_032349.1|ensembl:ENSMUSG00000002010(gene)|ensembl:ENSMUST00000052761(transcript)|go:"GO:0000287"(magnesium ion binding)|go:"GO:0004449"("isocitrate dehydrogenase (NAD+) activity")|go:"GO:0005524"(ATP binding)|go:"GO:0005730"(nucleolus)|go:"GO:0005739"(mitochondrion)|go:"GO:0006099"(tricarboxylic acid cycle)|go:"GO:0006102"(isocitrate metabolic process)|go:"GO:0006103"(2-oxoglutarate metabolic process)|go:"GO:0006734"(NADH metabolic process)|go:"GO:0045926"(negative regulation of growth)|go:"GO:0051287"(NAD binding)|interpro:IPR004434(Isocitrate dehydrogenase NAD-dependent, mitochondrial)|interpro:IPR019818|interpro:IPR024084|mint:P70404|reactome:R-MMU-71403	-	chain-seq-start:60|chain-seq-end:166	-	figure legend:ST1.1|comment:acid-eluted fraction|dataset:Rare diseases - Interactions investigated in the context of Rare genetic disease|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2020/12/04	2020/12/21	rogid:mvYK6+YgIN/WuGLBCWqsqPLfDyQ10090	rogid:0wCp92dH0hTrNyYmucC9Ob73aBU10090	rigid:Y12P/8lD0zKvIbifDxV5fTMn1mU	false	mutation:34-34	-	-	-	psi-mi:"MI:0082"(peptide massfingerprinting)	psi-mi:"MI:0082"(peptide massfingerprinting)
uniprotkb:P97493-PRO_0000034151	uniprotkb:P40936	intact:EBI-26567598	intact:EBI-1634510|uniprotkb:Q9CZ50|ensembl:ENSMUSP00000003569	psi-mi:p97493-pro_0000034151(display_long)|uniprotkb:Thioredoxin-2(gene name synonym)|uniprotkb:Txn2(gene name)|psi-mi:Txn2(display_short)	psi-mi:inmt_mouse(display_long)|uniprotkb:Inmt(gene name)|psi-mi:Inmt(display_short)|uniprotkb:Temt(gene name synonym)|uniprotkb:Aromatic alkylamine N-methyltransferase(gene name synonym)|uniprotkb:Thioether S-methyltransferase(gene name synonym)	psi-mi:"MI:0096"(pull down)	Chasapis et al. (2019)	pubmed:31018154|imex:IM-28571	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26499412|imex:IM-28571-21	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	intact:EBI-8354432(chain-parent)	refseq:NP_033375.1|ensembl:ENSMUSG00000003477(gene)|ensembl:ENSMUST00000003569(transcript)|go:"GO:0004790"(thioether S-methyltransferase activity)|go:"GO:0005829"(cytosol)|go:"GO:0008170"(N-methyltransferase activity)|go:"GO:0009308"(amine metabolic process)|go:"GO:0009636"(response to toxic substance)|go:"GO:0030748"(amine N-methyltransferase activity)|go:"GO:0032259"(methylation)|go:"GO:0098615"(dimethyl selenide methyltransferase activity)|go:"GO:0102707"("S-adenosyl-L-methionine:beta-alanine N-methyltransferase activity")|interpro:IPR000940(Methyltransferase, NNMT/PNMT/TEMT)|interpro:IPR025820|interpro:IPR029063|mint:P40936	-	chain-seq-start:60|chain-seq-end:166	-	figure legend:ST1.1|comment:acid-eluted fraction|dataset:Rare diseases - Interactions investigated in the context of Rare genetic disease|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2020/12/04	2020/12/21	rogid:mvYK6+YgIN/WuGLBCWqsqPLfDyQ10090	rogid:K/ppFCWhzvqMB6eI89nV+gbmR8E10090	rigid:Y12P/8lD0zKvIbifDxV5fTMn1mU	false	mutation:34-34	-	-	-	psi-mi:"MI:0082"(peptide massfingerprinting)	psi-mi:"MI:0082"(peptide massfingerprinting)
uniprotkb:P97493-PRO_0000034151	uniprotkb:Q8BMS1	intact:EBI-26567598	intact:EBI-299595|ensembl:ENSMUSP00000120976|intact:EBI-773355|uniprotkb:Q5U5Y5|uniprotkb:Q3TCY3|uniprotkb:Q8QZU4	psi-mi:p97493-pro_0000034151(display_long)|uniprotkb:Thioredoxin-2(gene name synonym)|uniprotkb:Txn2(gene name)|psi-mi:Txn2(display_short)	psi-mi:echa_mouse(display_long)|uniprotkb:Hadha(gene name)|psi-mi:Hadha(display_short)|uniprotkb:TP-alpha(gene name synonym)|uniprotkb:Monolysocardiolipin acyltransferase(gene name synonym)	psi-mi:"MI:0096"(pull down)	Chasapis et al. (2019)	pubmed:31018154|imex:IM-28571	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26499412|imex:IM-28571-21	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	intact:EBI-8354432(chain-parent)	ensembl:ENSMUSG00000025745(gene)|ensembl:ENSMUST00000156859(transcript)|go:"GO:0000062"(fatty-acyl-CoA binding)|go:"GO:0003857"(3-hydroxyacyl-CoA dehydrogenase activity)|go:"GO:0003988"(acetyl-CoA C-acyltransferase activity)|go:"GO:0004300"(enoyl-CoA hydratase activity)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0006635"(fatty acid beta-oxidation)|go:"GO:0016507"(mitochondrial fatty acid beta-oxidation multienzyme complex)|go:"GO:0070403"(NAD+ binding)|interpro:IPR001753(Crotonase, core)|interpro:IPR006108(3-hydroxyacyl-CoA dehydrogenase, C-terminal)|go:"GO:0016508"(long-chain-enoyl-CoA hydratase activity)|go:"GO:0016509"(long-chain-3-hydroxyacyl-CoA dehydrogenase activity)|go:"GO:0032868"(response to insulin)|interpro:IPR006176(3-hydroxyacyl-CoA dehydrogenase, NAD binding)|go:"GO:0035965"(cardiolipin acyl-chain remodeling)|interpro:IPR006180(3-hydroxyacyl-CoA dehydrogenase, conserved site)|go:"GO:0042493"|interpro:IPR008927(6-phosphogluconate dehydrogenase, C-terminal-like)|interpro:IPR012803(Fatty acid oxidation complex, alpha subunit, mitochondrial)|interpro:IPR018376|interpro:IPR029045|interpro:IPR036291|mint:Q8BMS1|reactome:R-MMU-1482798|reactome:R-MMU-77285|reactome:R-MMU-77305|reactome:R-MMU-77310|go:"GO:0042645"(mitochondrial nucleoid)|go:"GO:0044877"(protein-containing complex binding)|reactome:R-MMU-77346|reactome:R-MMU-77348|reactome:R-MMU-77350|go:"GO:0051287"(NAD binding)|refseq:NP_849209.1	-	chain-seq-start:60|chain-seq-end:166	-	figure legend:ST1.1|comment:acid-eluted fraction|dataset:Rare diseases - Interactions investigated in the context of Rare genetic disease|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2020/12/04	2020/12/21	rogid:mvYK6+YgIN/WuGLBCWqsqPLfDyQ10090	rogid:xOA1ht6+a9ZSKRvLr0d9U2uPW2s10090	rigid:Y12P/8lD0zKvIbifDxV5fTMn1mU	false	mutation:34-34	-	-	-	psi-mi:"MI:0082"(peptide massfingerprinting)	psi-mi:"MI:0082"(peptide massfingerprinting)
uniprotkb:P97493-PRO_0000034151	uniprotkb:P62827	intact:EBI-26567598	intact:EBI-286564|uniprotkb:Q3U954|uniprotkb:Q811M2|uniprotkb:Q86V08|uniprotkb:P17080|uniprotkb:P28746|uniprotkb:P28747|uniprotkb:Q9UDJ5|uniprotkb:Q9CSP3|uniprotkb:Q9CWI7|uniprotkb:Q9CZA2|uniprotkb:Q9UEU9|ensembl:ENSMUSP00000031383|ensembl:ENSMUSP00000106975	psi-mi:p97493-pro_0000034151(display_long)|uniprotkb:Thioredoxin-2(gene name synonym)|uniprotkb:Txn2(gene name)|psi-mi:Txn2(display_short)	psi-mi:ran_mouse(display_long)|uniprotkb:GTPase Ran(gene name synonym)|uniprotkb:Ras-related nuclear protein(gene name synonym)|uniprotkb:Ras-like protein TC4(gene name synonym)|uniprotkb:Ran(gene name)|psi-mi:Ran(display_short)|uniprotkb:Rasl2-8(gene name synonym)	psi-mi:"MI:0096"(pull down)	Chasapis et al. (2019)	pubmed:31018154|imex:IM-28571	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26499412|imex:IM-28571-21	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	intact:EBI-8354432(chain-parent)	refseq:NP_033417.1|refseq:XP_006504343.1|ensembl:ENSMUSG00000029430(gene)|ensembl:ENSMUST00000031383(transcript)|ensembl:ENSMUST00000111343(transcript)|go:"GO:0000054"(ribosomal subunit export from nucleus)|go:"GO:0000055"(ribosomal large subunit export from nucleus)|go:"GO:0000056"(ribosomal small subunit export from nucleus)|go:"GO:0000070"(mitotic sister chromatid segregation)|go:"GO:0000287"(magnesium ion binding)|go:"GO:0001673"(male germ cell nucleus)|go:"GO:0002177"(manchette)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005643"(nuclear pore)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005814"(centriole)|go:"GO:0005829"(cytosol)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0006611"(protein export from nucleus)|go:"GO:0019003"(GDP binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030036"(actin cytoskeleton organization)|go:"GO:0030496"(midbody)|go:"GO:0032092"(positive regulation of protein binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034613"(cellular protein localization)|go:"GO:0034629"|go:"GO:0036126"(sperm flagellum)|go:"GO:0042307"(positive regulation of protein import into nucleus)|go:"GO:0042470"(melanosome)|go:"GO:0042565"(RNA nuclear export complex)|go:"GO:0043393"(regulation of protein binding)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045505"(dynein intermediate chain binding)|go:"GO:0046039"(GTP metabolic process)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0051301"(cell division)|go:"GO:0055037"(recycling endosome)|go:"GO:0061015"(snRNA import into nucleus)|go:"GO:0061676"(importin-alpha family protein binding)|go:"GO:1902570"(protein localization to nucleolus)|interpro:IPR001806(Ras GTPase)|interpro:IPR002041(Ran GTPase)|interpro:IPR005225(Small GTP-binding protein)|interpro:IPR027417|mint:P62827|reactome:R-MMU-1655829|reactome:R-MMU-5578749|reactome:R-MMU-9615933	-	chain-seq-start:60|chain-seq-end:166	-	figure legend:ST1.1|comment:acid-eluted fraction|dataset:Rare diseases - Interactions investigated in the context of Rare genetic disease|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2020/12/04	2020/12/21	rogid:mvYK6+YgIN/WuGLBCWqsqPLfDyQ10090	rogid:trIUv5n3nI5d0rkfDTgw/6ubxMA10090	rigid:Y12P/8lD0zKvIbifDxV5fTMn1mU	false	mutation:34-34	-	-	-	psi-mi:"MI:0082"(peptide massfingerprinting)	psi-mi:"MI:0082"(peptide massfingerprinting)
uniprotkb:P97493-PRO_0000034151	uniprotkb:P16858	intact:EBI-26567598	intact:EBI-444871|uniprotkb:Q0QEU0|uniprotkb:Q3THM2|uniprotkb:Q3TUI2|uniprotkb:Q3UMT2|uniprotkb:Q4V783|uniprotkb:Q569X2|uniprotkb:Q569X5|uniprotkb:Q5U410|uniprotkb:A6H6A8|ensembl:ENSMUSP00000073289|ensembl:ENSMUSP00000113213	psi-mi:p97493-pro_0000034151(display_long)|uniprotkb:Thioredoxin-2(gene name synonym)|uniprotkb:Txn2(gene name)|psi-mi:Txn2(display_short)	psi-mi:g3p_mouse(display_long)|uniprotkb:Gapdh(gene name)|psi-mi:Gapdh(display_short)|uniprotkb:Gapd(gene name synonym)|uniprotkb:Peptidyl-cysteine S-nitrosylase GAPDH(gene name synonym)	psi-mi:"MI:0096"(pull down)	Chasapis et al. (2019)	pubmed:31018154|imex:IM-28571	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26499412|imex:IM-28571-21	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	intact:EBI-8354432(chain-parent)	refseq:NP_032110.1|refseq:XP_001476757.1|ensembl:ENSMUSG00000057666(gene)|ensembl:ENSMUST00000073605(transcript)|ensembl:ENSMUST00000118875(transcript)|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0001819"(positive regulation of cytokine production)|go:"GO:0004365"("glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity")|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005811"(lipid droplet)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005975"(carbohydrate metabolic process)|go:"GO:0006094"(gluconeogenesis)|go:"GO:0006096"(glycolytic process)|go:"GO:0006915"(apoptotic process)|go:"GO:0008017"(microtubule binding)|go:"GO:0010951"(negative regulation of endopeptidase activity)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0017148"(negative regulation of translation)|go:"GO:0019828"(aspartic-type endopeptidase inhibitor activity)|go:"GO:0019899"(enzyme binding)|go:"GO:0019933"(cAMP-mediated signaling)|go:"GO:0031640"(killing of cells of another organism)|go:"GO:0031906"(late endosome lumen)|go:"GO:0031965"(nuclear membrane)|go:"GO:0032481"(positive regulation of type I interferon production)|go:"GO:0035605"(peptidyl-cysteine S-nitrosylase activity)|go:"GO:0035606"(peptidyl-cysteine S-trans-nitrosylation)|go:"GO:0042802"(identical protein binding)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043209"(myelin sheath)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0050661"(NADP binding)|go:"GO:0050821"(protein stabilization)|go:"GO:0050832"(defense response to fungus)|go:"GO:0051287"(NAD binding)|go:"GO:0051402"(neuron apoptotic process)|go:"GO:0051873"(killing by host of symbiont cells)|go:"GO:0060359"(response to ammonium ion)|go:"GO:0061844"(antimicrobial humoral immune response mediated by antimicrobial peptide)|go:"GO:0071346"(cellular response to interferon-gamma)|go:"GO:0097452"(GAIT complex)|go:"GO:0097718"(disordered domain specific binding)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099092"(postsynaptic density, intracellular component)|go:"GO:1905460"(negative regulation of vascular associated smooth muscle cell apoptotic process)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR006424(Glyceraldehyde-3-phosphate dehydrogenase, type I)|interpro:IPR020828|interpro:IPR020829|interpro:IPR020830|interpro:IPR020831|interpro:IPR036291|mint:P16858|rcsb pdb:6LGJ|rcsb pdb:6LGK|rcsb pdb:6LGM|reactome:R-MMU-70171|reactome:R-MMU-70263|refseq:NP_001276655.1|dip:DIP-31404N	-	chain-seq-start:60|chain-seq-end:166	-	figure legend:ST1.1|comment:acid-eluted fraction|dataset:Rare diseases - Interactions investigated in the context of Rare genetic disease|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2020/12/04	2020/12/21	rogid:mvYK6+YgIN/WuGLBCWqsqPLfDyQ10090	rogid:SkcdXZ+143DDQFioo6mNWNpCLTI10090	rigid:Y12P/8lD0zKvIbifDxV5fTMn1mU	false	mutation:34-34	-	-	-	psi-mi:"MI:0082"(peptide massfingerprinting)	psi-mi:"MI:0082"(peptide massfingerprinting)
uniprotkb:P97493-PRO_0000034151	uniprotkb:P13020	intact:EBI-26567598	intact:EBI-445180|uniprotkb:Q3UPB1|uniprotkb:Q8R590|intact:EBI-4281654|ensembl:ENSMUSP00000028239	psi-mi:p97493-pro_0000034151(display_long)|uniprotkb:Thioredoxin-2(gene name synonym)|uniprotkb:Txn2(gene name)|psi-mi:Txn2(display_short)	psi-mi:gels_mouse(display_long)|uniprotkb:Actin-depolymerizing factor(gene name synonym)|uniprotkb:Brevin(gene name synonym)|uniprotkb:Gsn(gene name)|psi-mi:Gsn(display_short)|uniprotkb:Gsb(gene name synonym)	psi-mi:"MI:0096"(pull down)	Chasapis et al. (2019)	pubmed:31018154|imex:IM-28571	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26499412|imex:IM-28571-21	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	intact:EBI-8354432(chain-parent)	refseq:NP_666232.2|ensembl:ENSMUSG00000026879(gene)|ensembl:ENSMUST00000028239(transcript)|go:"GO:0001726"(ruffle)|go:"GO:0002102"(podosome)|go:"GO:0003779"(actin binding)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005546"(phosphatidylinositol-4,5-bisphosphate binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006911"(phagocytosis, engulfment)|go:"GO:0006915"(apoptotic process)|go:"GO:0007417"(central nervous system development)|go:"GO:0007568"(aging)|go:"GO:0008154"(actin polymerization or depolymerization)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0014003"(oligodendrocyte development)|go:"GO:0014891"(striated muscle atrophy)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0016192"(vesicle-mediated transport)|go:"GO:0016528"(sarcoplasm)|go:"GO:0030027"(lamellipodium)|go:"GO:0030031"(cell projection assembly)|go:"GO:0030036"(actin cytoskeleton organization)|go:"GO:0030041"(actin filament polymerization)|go:"GO:0030042"(actin filament depolymerization)|go:"GO:0030155"(regulation of cell adhesion)|go:"GO:0030478"(actin cap)|go:"GO:0030864"(cortical actin cytoskeleton)|go:"GO:0031648"(protein destabilization)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035994"(response to muscle stretch)|go:"GO:0036313"(phosphatidylinositol 3-kinase catalytic subunit binding)|go:"GO:0042060"(wound healing)|go:"GO:0042246"(tissue regeneration)|go:"GO:0042989"(sequestering of actin monomers)|go:"GO:0043209"(myelin sheath)|go:"GO:0045010"(actin nucleation)|go:"GO:0045159"(myosin II binding)|go:"GO:0045335"(phagocytic vesicle)|go:"GO:0045471"(response to ethanol)|go:"GO:0046597"(negative regulation of viral entry into host cell)|go:"GO:0048015"(phosphatidylinositol-mediated signaling)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051014"(actin filament severing)|go:"GO:0051015"(actin filament binding)|go:"GO:0051016"(barbed-end actin filament capping)|go:"GO:0051127"(positive regulation of actin nucleation)|go:"GO:0051593"(response to folic acid)|go:"GO:0051693"(actin filament capping)|go:"GO:0055119"(relaxation of cardiac muscle)|go:"GO:0060271"(cilium assembly)|go:"GO:0071276"(cellular response to cadmium ion)|go:"GO:0071346"(cellular response to interferon-gamma)|go:"GO:0071801"(regulation of podosome assembly)|go:"GO:0086003"(cardiac muscle cell contraction)|go:"GO:0090527"(actin filament reorganization)|go:"GO:0097017"(renal protein absorption)|go:"GO:0097284"(hepatocyte apoptotic process)|go:"GO:1902174"(positive regulation of keratinocyte apoptotic process)|go:"GO:1903903"(regulation of establishment of T cell polarity)|go:"GO:1903906"(regulation of plasma membrane raft polarization)|go:"GO:1903909"(regulation of receptor clustering)|go:"GO:1903923"(positive regulation of protein processing in phagocytic vesicle)|go:"GO:1990000"(amyloid fibril formation)|go:"GO:2001269"(positive regulation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway)|interpro:IPR007122(Gelsolin)|interpro:IPR007123(Gelsolin region)|interpro:IPR029006|interpro:IPR030004|mint:P13020|rcsb pdb:1NPH|rcsb pdb:4CBU|rcsb pdb:4CBW|rcsb pdb:4CBX|rcsb pdb:5MVV|rcsb pdb:6I4D|rcsb pdb:6I4E|rcsb pdb:6I4F|rcsb pdb:6I4G|rcsb pdb:6I4H|rcsb pdb:6I4I|rcsb pdb:6I4J|rcsb pdb:6I4K|rcsb pdb:6I4L|rcsb pdb:6I4M|reactome:R-MMU-264870|reactome:R-MMU-6798695|dip:DIP-31941N	-	chain-seq-start:60|chain-seq-end:166	-	figure legend:ST1.1|comment:acid-eluted fraction|dataset:Rare diseases - Interactions investigated in the context of Rare genetic disease|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2020/12/04	2020/12/21	rogid:mvYK6+YgIN/WuGLBCWqsqPLfDyQ10090	rogid:vByKB6qbsPzebkkufeXoP6n0SUI10090	rigid:Y12P/8lD0zKvIbifDxV5fTMn1mU	false	mutation:34-34	-	-	-	psi-mi:"MI:0082"(peptide massfingerprinting)	psi-mi:"MI:0082"(peptide massfingerprinting)
uniprotkb:P97493-PRO_0000034151	uniprotkb:P47754	intact:EBI-26567598	intact:EBI-299188|ensembl:ENSMUSP00000015877	psi-mi:p97493-pro_0000034151(display_long)|uniprotkb:Thioredoxin-2(gene name synonym)|uniprotkb:Txn2(gene name)|psi-mi:Txn2(display_short)	psi-mi:caza2_mouse(display_long)|uniprotkb:Capza2(gene name)|psi-mi:Capza2(display_short)|uniprotkb:Cappa2(gene name synonym)|uniprotkb:CapZ alpha-2(gene name synonym)	psi-mi:"MI:0096"(pull down)	Chasapis et al. (2019)	pubmed:31018154|imex:IM-28571	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26499412|imex:IM-28571-21	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	intact:EBI-8354432(chain-parent)	ensembl:ENSMUST00000015877(transcript)|go:"GO:0005829"(cytosol)|go:"GO:0005903"(brush border)|go:"GO:0008290"(F-actin capping protein complex)|go:"GO:0016020"(membrane)|go:"GO:0030036"(actin cytoskeleton organization)|go:"GO:0030863"(cortical cytoskeleton)|go:"GO:0051015"(actin filament binding)|go:"GO:0051016"(barbed-end actin filament capping)|interpro:IPR002189(F-actin capping protein, alpha subunit)|interpro:IPR017865|interpro:IPR037282|interpro:IPR042276|interpro:IPR042489|mint:P47754|reactome:R-MMU-2132295|reactome:R-MMU-3371497|reactome:R-MMU-6807878|reactome:R-MMU-6811436|reactome:R-MMU-879415|reactome:R-MMU-983231|ensembl:ENSMUSG00000015733(gene)|refseq:NP_031630.1|dip:DIP-31382N	-	chain-seq-start:60|chain-seq-end:166	-	figure legend:ST1.1|comment:acid-eluted fraction|dataset:Rare diseases - Interactions investigated in the context of Rare genetic disease|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2020/12/04	2020/12/21	rogid:mvYK6+YgIN/WuGLBCWqsqPLfDyQ10090	rogid:9nxfEbrpHlDtTYwSvHAJvZLLweo10090	rigid:Y12P/8lD0zKvIbifDxV5fTMn1mU	false	mutation:34-34	-	-	-	psi-mi:"MI:0082"(peptide massfingerprinting)	psi-mi:"MI:0082"(peptide massfingerprinting)
uniprotkb:P97493-PRO_0000034151	uniprotkb:P47753	intact:EBI-26567598	intact:EBI-777259|uniprotkb:Q91YN7	psi-mi:p97493-pro_0000034151(display_long)|uniprotkb:Thioredoxin-2(gene name synonym)|uniprotkb:Txn2(gene name)|psi-mi:Txn2(display_short)	psi-mi:caza1_mouse(display_long)|uniprotkb:CapZ alpha-1(gene name synonym)|uniprotkb:Capza1(gene name)|psi-mi:Capza1(display_short)|uniprotkb:Cappa1(gene name synonym)	psi-mi:"MI:0096"(pull down)	Chasapis et al. (2019)	pubmed:31018154|imex:IM-28571	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26499412|imex:IM-28571-21	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	intact:EBI-8354432(chain-parent)	interpro:IPR017865|interpro:IPR002189(F-actin capping protein, alpha subunit)|interpro:IPR042276|interpro:IPR037282|mint:P47753|interpro:IPR042489|go:"GO:0003779"(actin binding)|go:"GO:0005829"(cytosol)|go:"GO:0005903"(brush border)|go:"GO:0005911"(cell-cell junction)|go:"GO:0008290"(F-actin capping protein complex)|go:"GO:0016020"(membrane)|go:"GO:0030036"(actin cytoskeleton organization)|go:"GO:0030863"(cortical cytoskeleton)|go:"GO:0034329"(cell junction assembly)|go:"GO:0051016"(barbed-end actin filament capping)|go:"GO:0071203"(WASH complex)|reactome:R-MMU-2132295|reactome:R-MMU-3371497|reactome:R-MMU-6807878|reactome:R-MMU-6811436|reactome:R-MMU-879415|reactome:R-MMU-983231	-	chain-seq-start:60|chain-seq-end:166	-	figure legend:ST1.1|comment:acid-eluted fraction|dataset:Rare diseases - Interactions investigated in the context of Rare genetic disease|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2020/12/04	2020/12/21	rogid:mvYK6+YgIN/WuGLBCWqsqPLfDyQ10090	rogid:RHqr2/WSAoIXWooDhXO9/TSiTJ010090	rigid:Y12P/8lD0zKvIbifDxV5fTMn1mU	false	mutation:34-34	-	-	-	psi-mi:"MI:0082"(peptide massfingerprinting)	psi-mi:"MI:0082"(peptide massfingerprinting)
uniprotkb:P97493-PRO_0000034151	uniprotkb:Q62188	intact:EBI-26567598	intact:EBI-6665513|ensembl:ENSMUSP00000025379	psi-mi:p97493-pro_0000034151(display_long)|uniprotkb:Thioredoxin-2(gene name synonym)|uniprotkb:Txn2(gene name)|psi-mi:Txn2(display_short)	psi-mi:dpyl3_mouse(display_long)|uniprotkb:Dpysl3(gene name)|psi-mi:Dpysl3(display_short)|uniprotkb:Drp3(gene name synonym)|uniprotkb:Ulip(gene name synonym)|uniprotkb:Unc-33-like phosphoprotein 1(gene name synonym)	psi-mi:"MI:0096"(pull down)	Chasapis et al. (2019)	pubmed:31018154|imex:IM-28571	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26499412|imex:IM-28571-21	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	intact:EBI-8354432(chain-parent)	ensembl:ENSMUSG00000024501(gene)|ensembl:ENSMUST00000025379(transcript)|go:"GO:0005615"(extracellular space)|go:"GO:0005829"(cytosol)|go:"GO:0007399"(nervous system development)|go:"GO:0010976"(positive regulation of neuron projection development)|go:"GO:0010977"(negative regulation of neuron projection development)|go:"GO:0016810"("hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds")|go:"GO:0017124"(SH3 domain binding)|go:"GO:0030027"(lamellipodium)|go:"GO:0030336"(negative regulation of cell migration)|go:"GO:0031005"(filamin binding)|go:"GO:0031941"(filamentous actin)|go:"GO:0035374"(chondroitin sulfate binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0044297"(cell body)|go:"GO:0045202"(synapse)|go:"GO:0048678"(response to axon injury)|go:"GO:0051017"(actin filament bundle assembly)|go:"GO:0051219"(phosphoprotein binding)|go:"GO:0051491"(positive regulation of filopodium assembly)|go:"GO:0051764"(actin crosslink formation)|go:"GO:0071345"(cellular response to cytokine stimulus)|interpro:IPR006680(Amidohydrolase 1)|interpro:IPR011059(Metal-dependent hydrolase, composite)|interpro:IPR011778(D-hydantoinase)|interpro:IPR030628|interpro:IPR032466|mint:Q62188|reactome:R-MMU-399956|go:"GO:0030426"(growth cone)|refseq:NP_033494.1	-	chain-seq-start:60|chain-seq-end:166	-	figure legend:ST1.1|comment:acid-eluted fraction|dataset:Rare diseases - Interactions investigated in the context of Rare genetic disease|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2020/12/04	2020/12/21	rogid:mvYK6+YgIN/WuGLBCWqsqPLfDyQ10090	rogid:r4kvo421vO21dxYaOQ8P7f6AL4Y10090	rigid:Y12P/8lD0zKvIbifDxV5fTMn1mU	false	mutation:34-34	-	-	-	psi-mi:"MI:0082"(peptide massfingerprinting)	psi-mi:"MI:0082"(peptide massfingerprinting)
uniprotkb:P97493-PRO_0000034151	uniprotkb:P62702	intact:EBI-26567598	intact:EBI-354261|uniprotkb:P12631|uniprotkb:P12750|uniprotkb:P27576|uniprotkb:Q9CXN0|uniprotkb:P55831|uniprotkb:Q14727|ensembl:ENSMUSP00000033683	psi-mi:p97493-pro_0000034151(display_long)|uniprotkb:Thioredoxin-2(gene name synonym)|uniprotkb:Txn2(gene name)|psi-mi:Txn2(display_short)	psi-mi:rs4x_mouse(display_long)|uniprotkb:Rps4(gene name synonym)|uniprotkb:Rps4x(gene name)|psi-mi:Rps4x(display_short)	psi-mi:"MI:0096"(pull down)	Chasapis et al. (2019)	pubmed:31018154|imex:IM-28571	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26499412|imex:IM-28571-21	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	intact:EBI-8354432(chain-parent)	refseq:NP_033120.1|reactome:R-MMU-1799339|reactome:R-MMU-6791226|reactome:R-MMU-72649|reactome:R-MMU-72689|reactome:R-MMU-72695|reactome:R-MMU-72702|reactome:R-MMU-72706|reactome:R-MMU-975956|reactome:R-MMU-975957|ensembl:ENSMUSG00000031320(gene)|ensembl:ENSMUST00000033683(transcript)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005829"(cytosol)|go:"GO:0005840"(ribosome)|go:"GO:0005844"(polysome)|go:"GO:0006412"(translation)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0015935"(small ribosomal subunit)|go:"GO:0019843"(rRNA binding)|go:"GO:0022627"(cytosolic small ribosomal subunit)|go:"GO:0036464"(cytoplasmic ribonucleoprotein granule)|go:"GO:0045202"(synapse)|go:"GO:0045727"(positive regulation of translation)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR000876(Ribosomal protein S4e)|interpro:IPR002942(RNA-binding S4)|interpro:IPR005824(KOW)|interpro:IPR013843(Ribosomal protein S4e, N-terminal)|interpro:IPR013845(Ribosomal protein S4e, central)|interpro:IPR014722(Translation protein SH3-like, subgroup)|interpro:IPR018199|interpro:IPR032277|interpro:IPR036986|interpro:IPR038237|interpro:IPR041982|mint:P62702|reactome:R-MMU-156827|go:"GO:0003723"(RNA binding)	-	chain-seq-start:60|chain-seq-end:166	-	figure legend:ST1.1|comment:acid-eluted fraction|dataset:Rare diseases - Interactions investigated in the context of Rare genetic disease|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2020/12/04	2020/12/21	rogid:mvYK6+YgIN/WuGLBCWqsqPLfDyQ10090	rogid:2ZuLXqBSDkK0CtN3mnIDoFAR8yI10090	rigid:Y12P/8lD0zKvIbifDxV5fTMn1mU	false	mutation:34-34	-	-	-	psi-mi:"MI:0082"(peptide massfingerprinting)	psi-mi:"MI:0082"(peptide massfingerprinting)
uniprotkb:P97493-PRO_0000034151	uniprotkb:Q8VDJ3	intact:EBI-26567598	intact:EBI-8317711|intact:MINT-1858511|ensembl:ENSMUSP00000043047|ensembl:ENSMUSP00000127903	psi-mi:p97493-pro_0000034151(display_long)|uniprotkb:Thioredoxin-2(gene name synonym)|uniprotkb:Txn2(gene name)|psi-mi:Txn2(display_short)	psi-mi:vigln_mouse(display_long)|uniprotkb:Hdlbp(gene name)|psi-mi:Hdlbp(display_short)|uniprotkb:High density lipoprotein-binding protein(gene name synonym)	psi-mi:"MI:0096"(pull down)	Chasapis et al. (2019)	pubmed:31018154|imex:IM-28571	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26499997|imex:IM-28571-41	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	intact:EBI-8354432(chain-parent)	refseq:NP_001288293.1|refseq:NP_598569.1|refseq:XP_006529137.1|refseq:XP_006529138.1|refseq:XP_006529139.1|refseq:XP_006529140.1|ensembl:ENSMUSG00000034088(gene)|ensembl:ENSMUST00000042498(transcript)|ensembl:ENSMUST00000170883(transcript)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005844"(polysome)|go:"GO:0006869"(lipid transport)|go:"GO:0008203"(cholesterol metabolic process)|go:"GO:0034364"(high-density lipoprotein particle)|interpro:IPR004087(K Homology)|interpro:IPR004088(K Homology, type 1)|interpro:IPR036612|mint:Q8VDJ3|reactome:R-MMU-8964011	-	chain-seq-start:60|chain-seq-end:166	function:Appears to play a role in cell sterol metabolism. It may function to protect cells from over-accumulation of cholesterol|comment:mint	figure legend:ST1.2|comment:DTT-eluted fraction|dataset:Rare diseases - Interactions investigated in the context of Rare genetic disease|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2020/12/04	2020/12/21	rogid:mvYK6+YgIN/WuGLBCWqsqPLfDyQ10090	rogid:H8VW/Tp0f9b24nwslsUWF+CW/xE10090	rigid:sUlyHN3eQirg+yWIik/3UpGEVS4	false	mutation:34-34	-	-	-	psi-mi:"MI:0082"(peptide massfingerprinting)	psi-mi:"MI:0082"(peptide massfingerprinting)
uniprotkb:P97493-PRO_0000034151	uniprotkb:P17563	intact:EBI-26567598	intact:EBI-8362477|uniprotkb:Q91X87|intact:MINT-1854683|ensembl:ENSMUSP00000088349	psi-mi:p97493-pro_0000034151(display_long)|uniprotkb:Thioredoxin-2(gene name synonym)|uniprotkb:Txn2(gene name)|psi-mi:Txn2(display_short)	psi-mi:sbp1_mouse(display_long)|uniprotkb:Selenbp1(gene name)|psi-mi:Selenbp1(display_short)|uniprotkb:Lpsb(gene name synonym)|uniprotkb:56 kDa selenium-binding protein(gene name synonym)|uniprotkb:Selenium-binding protein 1(gene name synonym)	psi-mi:"MI:0096"(pull down)	Chasapis et al. (2019)	pubmed:31018154|imex:IM-28571	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26499997|imex:IM-28571-41	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	intact:EBI-8354432(chain-parent)	refseq:NP_033176.2|ensembl:ENSMUSG00000068874(gene)|ensembl:ENSMUST00000090839(transcript)|go:"GO:0001650"(fibrillar center)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0008430"(selenium binding)|go:"GO:0015031"(protein transport)|go:"GO:0016020"(membrane)|go:"GO:0018549"(methanethiol oxidase activity)|go:"GO:0050873"(brown fat cell differentiation)|interpro:IPR008826(Selenium-binding protein)|mint:P17563	-	chain-seq-start:60|chain-seq-end:166	comment:mint|function:Selenium-binding protein which may be involved in the sensing of reactive xenobiotics in the cytoplasm. May be involved in intra-Golgi protein transport	figure legend:ST1.2|comment:DTT-eluted fraction|dataset:Rare diseases - Interactions investigated in the context of Rare genetic disease|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2020/12/04	2020/12/21	rogid:mvYK6+YgIN/WuGLBCWqsqPLfDyQ10090	rogid:/sDrAhh3tD4jaVfdnMSfJSeGAqQ10090	rigid:sUlyHN3eQirg+yWIik/3UpGEVS4	false	mutation:34-34	-	-	-	psi-mi:"MI:0082"(peptide massfingerprinting)	psi-mi:"MI:0082"(peptide massfingerprinting)
uniprotkb:P97493-PRO_0000034151	uniprotkb:Q9QVP4	intact:EBI-26567598	intact:EBI-8357276|uniprotkb:Q9JIE8|intact:MINT-4102168|uniprotkb:Q63977|ensembl:ENSMUSP00000099985	psi-mi:p97493-pro_0000034151(display_long)|uniprotkb:Thioredoxin-2(gene name synonym)|uniprotkb:Txn2(gene name)|psi-mi:Txn2(display_short)	psi-mi:mlra_mouse(display_long)|uniprotkb:Myl7(gene name)|psi-mi:Myl7(display_short)|uniprotkb:Mylc2a(gene name synonym)|uniprotkb:Myosin regulatory light chain 7(gene name synonym)	psi-mi:"MI:0096"(pull down)	Chasapis et al. (2019)	pubmed:31018154|imex:IM-28571	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26499997|imex:IM-28571-41	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	intact:EBI-8354432(chain-parent)	refseq:NP_075017.2|ensembl:ENSMUSG00000020469(gene)|ensembl:ENSMUST00000102921(transcript)|go:"GO:0005509"(calcium ion binding)|go:"GO:0016459"(myosin complex)|go:"GO:0031672"(A band)|go:"GO:0043197"(dendritic spine)|interpro:IPR002048(Calcium-binding EF-hand)|interpro:IPR011992(EF-Hand type)|interpro:IPR018247|mint:Q9QVP4|reactome:R-MMU-445355	-	chain-seq-start:60|chain-seq-end:166	comment:mint	figure legend:ST1.2|comment:DTT-eluted fraction|dataset:Rare diseases - Interactions investigated in the context of Rare genetic disease|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2020/12/04	2020/12/21	rogid:mvYK6+YgIN/WuGLBCWqsqPLfDyQ10090	rogid:leuWAVQCkKG0daoyT4BpClk7lyc10090	rigid:sUlyHN3eQirg+yWIik/3UpGEVS4	false	mutation:34-34	-	-	-	psi-mi:"MI:0082"(peptide massfingerprinting)	psi-mi:"MI:0082"(peptide massfingerprinting)
uniprotkb:P97493-PRO_0000034151	uniprotkb:Q9CR00	intact:EBI-26567598	intact:EBI-8315743|ensembl:ENSMUSP00000098295|intact:MINT-1864323|uniprotkb:Q3TG66	psi-mi:p97493-pro_0000034151(display_long)|uniprotkb:Thioredoxin-2(gene name synonym)|uniprotkb:Txn2(gene name)|psi-mi:Txn2(display_short)	psi-mi:psmd9_mouse(display_long)|uniprotkb:Psmd9(gene name)|psi-mi:Psmd9(display_short)|uniprotkb:26S proteasome regulatory subunit p27(gene name synonym)	psi-mi:"MI:0096"(pull down)	Chasapis et al. (2019)	pubmed:31018154|imex:IM-28571	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26499997|imex:IM-28571-41	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	intact:EBI-8354432(chain-parent)	ensembl:ENSMUSG00000029440(gene)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046676"(negative regulation of insulin secretion)|go:"GO:0070682"(proteasome regulatory particle assembly)|go:"GO:0097050"(type B pancreatic cell apoptotic process)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR035269|interpro:IPR036034|interpro:IPR040815|interpro:IPR041489|mint:Q9CR00|reactome:R-MMU-1169091|reactome:R-MMU-1234176|reactome:R-MMU-1236978|reactome:R-MMU-174084|reactome:R-MMU-174154|reactome:R-MMU-174178|reactome:R-MMU-174184|reactome:R-MMU-187577|reactome:R-MMU-195253|reactome:R-MMU-202424|reactome:R-MMU-2467813|reactome:R-MMU-2871837|reactome:R-MMU-349425|reactome:R-MMU-350562|reactome:R-MMU-382556|reactome:R-MMU-450408|reactome:R-MMU-4608870|reactome:R-MMU-4641257|reactome:R-MMU-4641258|reactome:R-MMU-5358346|reactome:R-MMU-5607761|reactome:R-MMU-5607764|reactome:R-MMU-5610780|reactome:R-MMU-5610785|reactome:R-MMU-5632684|reactome:R-MMU-5658442|reactome:R-MMU-5668541|reactome:R-MMU-5676590|reactome:R-MMU-5687128|reactome:R-MMU-5689603|reactome:R-MMU-5689880|reactome:R-MMU-68827|reactome:R-MMU-68949|reactome:R-MMU-69017|reactome:R-MMU-69481|reactome:R-MMU-69601|reactome:R-MMU-75815|reactome:R-MMU-8852276|reactome:R-MMU-8854050|reactome:R-MMU-8932339|reactome:R-MMU-8939236|reactome:R-MMU-8939902|reactome:R-MMU-8941858|reactome:R-MMU-8948751|reactome:R-MMU-8951664|reactome:R-MMU-9020702|reactome:R-MMU-983168|ensembl:ENSMUST00000100729(transcript)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0032024"(positive regulation of insulin secretion)|go:"GO:0043425"(bHLH transcription factor binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|refseq:NP_080276.2	-	chain-seq-start:60|chain-seq-end:166	function:Acts as a regulatory subunit of the 26S proteasome which is involved in the ATP-dependent degradation of ubiquitinated proteins|comment:mint	figure legend:ST1.2|comment:DTT-eluted fraction|dataset:Rare diseases - Interactions investigated in the context of Rare genetic disease|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2020/12/04	2020/12/21	rogid:mvYK6+YgIN/WuGLBCWqsqPLfDyQ10090	rogid:DUglm9j1ZR4yDeQBQqg4IBQ3EmQ10090	rigid:sUlyHN3eQirg+yWIik/3UpGEVS4	false	mutation:34-34	-	-	-	psi-mi:"MI:0082"(peptide massfingerprinting)	psi-mi:"MI:0082"(peptide massfingerprinting)
uniprotkb:P97493-PRO_0000034151	uniprotkb:Q9D154	intact:EBI-26567598	intact:EBI-8392973|uniprotkb:Q9D0S8|uniprotkb:Q3TV23|uniprotkb:Q5SUV7|intact:MINT-4127525|uniprotkb:Q9D7S8|ensembl:ENSMUSP00000075690	psi-mi:p97493-pro_0000034151(display_long)|uniprotkb:Thioredoxin-2(gene name synonym)|uniprotkb:Txn2(gene name)|psi-mi:Txn2(display_short)	psi-mi:ileua_mouse(display_long)|uniprotkb:Serpinb1a(gene name)|psi-mi:Serpinb1a(display_short)|uniprotkb:Serpinb1(gene name synonym)|uniprotkb:Serine protease inhibitor EIA(gene name synonym)|uniprotkb:Serpin B1a(gene name synonym)	psi-mi:"MI:0096"(pull down)	Chasapis et al. (2019)	pubmed:31018154|imex:IM-28571	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26499997|imex:IM-28571-41	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	intact:EBI-8354432(chain-parent)	refseq:NP_079705.2|refseq:XP_006516787.1|ensembl:ENSMUSG00000044734(gene)|ensembl:ENSMUST00000076352(transcript)|go:"GO:0004867"(serine-type endopeptidase inhibitor activity)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0005764"(lysosome)|go:"GO:0005769"(early endosome)|go:"GO:0006954"(inflammatory response)|go:"GO:0010951"(negative regulation of endopeptidase activity)|go:"GO:0019725"(cellular homeostasis)|go:"GO:0030414"(peptidase inhibitor activity)|go:"GO:0032691"(negative regulation of interleukin-1 beta production)|go:"GO:0036464"(cytoplasmic ribonucleoprotein granule)|go:"GO:0042176"(regulation of protein catabolic process)|go:"GO:0044342"(type B pancreatic cell proliferation)|go:"GO:0045088"(regulation of innate immune response)|go:"GO:0062023"(collagen-containing extracellular matrix)|interpro:IPR000215(Protease inhibitor I4, serpin)|interpro:IPR015557(Protease inhibitor I4, serpin B1)|interpro:IPR023795|interpro:IPR023796|interpro:IPR036186|interpro:IPR042178|interpro:IPR042185|mint:Q9D154|reactome:R-MMU-6798695	-	chain-seq-start:60|chain-seq-end:166	comment:mint|function:Regulates the activity of the neutrophil proteases and thus, forms complexes with chymotrypsin, elastase, cathepsin G and proteinase-3	figure legend:ST1.2|comment:DTT-eluted fraction|dataset:Rare diseases - Interactions investigated in the context of Rare genetic disease|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2020/12/04	2020/12/21	rogid:mvYK6+YgIN/WuGLBCWqsqPLfDyQ10090	rogid:L579vV8/0N4vGTUpzFi9vZ4lD0E10090	rigid:sUlyHN3eQirg+yWIik/3UpGEVS4	false	mutation:34-34	-	-	-	psi-mi:"MI:0082"(peptide massfingerprinting)	psi-mi:"MI:0082"(peptide massfingerprinting)
uniprotkb:P97493-PRO_0000034151	uniprotkb:Q91VM9	intact:EBI-26567598	intact:EBI-8317971|uniprotkb:Q3UPK3|uniprotkb:Q9D1E3|uniprotkb:Q8BTG5|intact:MINT-1843615|ensembl:ENSMUSP00000029644	psi-mi:p97493-pro_0000034151(display_long)|uniprotkb:Thioredoxin-2(gene name synonym)|uniprotkb:Txn2(gene name)|psi-mi:Txn2(display_short)	psi-mi:ipyr2_mouse(display_long)|uniprotkb:Ppa2(gene name)|psi-mi:Ppa2(display_short)|uniprotkb:Pyrophosphate phospho-hydrolase 2(gene name synonym)	psi-mi:"MI:0096"(pull down)	Chasapis et al. (2019)	pubmed:31018154|imex:IM-28571	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26499997|imex:IM-28571-41	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	intact:EBI-8354432(chain-parent)	refseq:NP_666253.1|refseq:NP_001280570.1|ensembl:ENSMUSG00000028013(gene)|ensembl:ENSMUST00000029644(transcript)|go:"GO:0000287"(magnesium ion binding)|go:"GO:0004427"(inorganic diphosphatase activity)|go:"GO:0004722"(protein serine/threonine phosphatase activity)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0006796"(phosphate-containing compound metabolic process)|go:"GO:0051881"(regulation of mitochondrial membrane potential)|go:"GO:0071344"(diphosphate metabolic process)|interpro:IPR008162(Inorganic pyrophosphatase)|interpro:IPR036649|mint:Q91VM9|reactome:R-MMU-379726|reactome:R-MMU-71737	-	chain-seq-start:60|chain-seq-end:166	comment:mint	figure legend:ST1.2|comment:DTT-eluted fraction|dataset:Rare diseases - Interactions investigated in the context of Rare genetic disease|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2020/12/04	2020/12/21	rogid:mvYK6+YgIN/WuGLBCWqsqPLfDyQ10090	rogid:+E5gorcOyQuWIKOl+IMas9/inRM10090	rigid:sUlyHN3eQirg+yWIik/3UpGEVS4	false	mutation:34-34	-	-	-	psi-mi:"MI:0082"(peptide massfingerprinting)	psi-mi:"MI:0082"(peptide massfingerprinting)
uniprotkb:P97493-PRO_0000034151	uniprotkb:Q61249	intact:EBI-26567598	intact:EBI-7002233|ensembl:ENSMUSP00000033570|intact:MINT-4597261	psi-mi:p97493-pro_0000034151(display_long)|uniprotkb:Thioredoxin-2(gene name synonym)|uniprotkb:Txn2(gene name)|psi-mi:Txn2(display_short)	psi-mi:igbp1_mouse(display_long)|uniprotkb:Igbp1(gene name)|psi-mi:Igbp1(display_short)|uniprotkb:Pc52(gene name synonym)|uniprotkb:Protein phosphatase 2/4/6 regulatory subunit(gene name synonym)|uniprotkb:CD79a-binding protein 1(gene name synonym)|uniprotkb:Alpha4 phosphoprotein(gene name synonym)|uniprotkb:Lymphocyte signal transduction molecule alpha 4(gene name synonym)|uniprotkb:p52(gene name synonym)	psi-mi:"MI:0096"(pull down)	Chasapis et al. (2019)	pubmed:31018154|imex:IM-28571	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26499997|imex:IM-28571-41	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	intact:EBI-8354432(chain-parent)	ensembl:ENSMUSG00000031221(gene)|ensembl:ENSMUST00000033570(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005874"(microtubule)|go:"GO:0019888"(protein phosphatase regulator activity)|go:"GO:0019899"(enzyme binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0031434"(mitogen-activated protein kinase kinase binding)|go:"GO:0032873"(negative regulation of stress-activated MAPK cascade)|go:"GO:0034612"(response to tumor necrosis factor)|go:"GO:0035303"(regulation of dephosphorylation)|go:"GO:0035306"(positive regulation of dephosphorylation)|go:"GO:0035308"(negative regulation of protein dephosphorylation)|go:"GO:0042113"(B cell activation)|go:"GO:0043154"(negative regulation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0051721"(protein phosphatase 2A binding)|go:"GO:0060632"(regulation of microtubule-based movement)|go:"GO:0070555"(response to interleukin-1)|go:"GO:2001234"(negative regulation of apoptotic signaling pathway)|interpro:IPR007304(TAP42-like protein)|interpro:IPR038511|mint:Q61249|rcsb pdb:3QC1|refseq:NP_032810.4	-	chain-seq-start:60|chain-seq-end:166	comment:mint|comment:homomint|function:Associated to surface IgM-receptor; may be involved in signal transduction. May be involved in regulation of the catalytic activity of type 2A-related serine/threonine phosphatases	figure legend:ST1.2|comment:DTT-eluted fraction|dataset:Rare diseases - Interactions investigated in the context of Rare genetic disease|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2020/12/04	2020/12/21	rogid:mvYK6+YgIN/WuGLBCWqsqPLfDyQ10090	rogid:ff6HGCQCC1YpTFCUPDMACHww2E010090	rigid:sUlyHN3eQirg+yWIik/3UpGEVS4	false	mutation:34-34	-	-	-	psi-mi:"MI:0082"(peptide massfingerprinting)	psi-mi:"MI:0082"(peptide massfingerprinting)
uniprotkb:P97493-PRO_0000034151	uniprotkb:O09164	intact:EBI-26567598	intact:EBI-8394218|intact:MINT-4135206|ensembl:ENSMUSP00000098768	psi-mi:p97493-pro_0000034151(display_long)|uniprotkb:Thioredoxin-2(gene name synonym)|uniprotkb:Txn2(gene name)|psi-mi:Txn2(display_short)	psi-mi:sode_mouse(display_long)|uniprotkb:Sod3(gene name)|psi-mi:Sod3(display_short)	psi-mi:"MI:0096"(pull down)	Chasapis et al. (2019)	pubmed:31018154|imex:IM-28571	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26499997|imex:IM-28571-41	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	intact:EBI-8354432(chain-parent)	refseq:NP_035565.1|ensembl:ENSMUSG00000072941(gene)|ensembl:ENSMUST00000101208(transcript)|go:"GO:0001666"(response to hypoxia)|go:"GO:0004784"(superoxide dismutase activity)|go:"GO:0005507"(copper ion binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005796"(Golgi lumen)|go:"GO:0019430"(removal of superoxide radicals)|go:"GO:0046688"(response to copper ion)|go:"GO:0062023"(collagen-containing extracellular matrix)|go:"GO:0097746"(blood vessel diameter maintenance)|interpro:IPR001424(Superoxide dismutase, copper/zinc binding)|interpro:IPR018152|interpro:IPR024134|interpro:IPR024141|interpro:IPR036423|mint:O09164|rcsb pdb:2DZ2|reactome:R-MMU-3299685|rcsb pdb:2DZ3	-	chain-seq-start:60|chain-seq-end:166	function:Protect the extracellular space from toxic effect of reactive oxygen intermediates by converting superoxide radicals into hydrogen peroxide and oxygen|comment:mint	figure legend:ST1.2|comment:DTT-eluted fraction|dataset:Rare diseases - Interactions investigated in the context of Rare genetic disease|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2020/12/04	2020/12/21	rogid:mvYK6+YgIN/WuGLBCWqsqPLfDyQ10090	rogid:xfmvw43N7/7f1DgRy2EYLSZ3ChY10090	rigid:sUlyHN3eQirg+yWIik/3UpGEVS4	false	mutation:34-34	-	-	-	psi-mi:"MI:0082"(peptide massfingerprinting)	psi-mi:"MI:0082"(peptide massfingerprinting)
uniprotkb:P97493-PRO_0000034151	uniprotkb:Q9D7X3	intact:EBI-26567598	intact:EBI-8320546|intact:MINT-4093702|ensembl:ENSMUSP00000003612|ensembl:ENSMUSP00000102790	psi-mi:p97493-pro_0000034151(display_long)|uniprotkb:Thioredoxin-2(gene name synonym)|uniprotkb:Txn2(gene name)|psi-mi:Txn2(display_short)	psi-mi:dus3_mouse(display_long)|uniprotkb:Dusp3(gene name)|psi-mi:Dusp3(display_short)|uniprotkb:T-DSP11(gene name synonym)|uniprotkb:Vaccinia H1-related phosphatase(gene name synonym)	psi-mi:"MI:0096"(pull down)	Chasapis et al. (2019)	pubmed:31018154|imex:IM-28571	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26499997|imex:IM-28571-41	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	intact:EBI-8354432(chain-parent)	refseq:NP_082483.1|ensembl:ENSMUSG00000003518(gene)|ensembl:ENSMUST00000003612(transcript)|ensembl:ENSMUST00000107172(transcript)|go:"GO:0000188"(obsolete inactivation of MAPK activity)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0001772"(immunological synapse)|go:"GO:0004721"(phosphoprotein phosphatase activity)|go:"GO:0004725"(protein tyrosine phosphatase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006470"(protein dephosphorylation)|go:"GO:0008092"(cytoskeletal protein binding)|go:"GO:0008138"(protein tyrosine/serine/threonine phosphatase activity)|go:"GO:0016311"(dephosphorylation)|go:"GO:0016791"(phosphatase activity)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030336"(negative regulation of cell migration)|go:"GO:0030971"(receptor tyrosine kinase binding)|go:"GO:0033549"(MAP kinase phosphatase activity)|go:"GO:0035335"(peptidyl-tyrosine dephosphorylation)|go:"GO:0042059"(negative regulation of epidermal growth factor receptor signaling pathway)|go:"GO:0043409"(negative regulation of MAPK cascade)|go:"GO:0045931"(positive regulation of mitotic cell cycle)|go:"GO:0046329"(negative regulation of JNK cascade)|go:"GO:0050860"(negative regulation of T cell receptor signaling pathway)|go:"GO:0050868"(negative regulation of T cell activation)|go:"GO:0050922"(negative regulation of chemotaxis)|go:"GO:0051893"(regulation of focal adhesion assembly)|go:"GO:0070373"(negative regulation of ERK1 and ERK2 cascade)|go:"GO:0071364"(cellular response to epidermal growth factor stimulus)|go:"GO:0106306"|go:"GO:0106307"|go:"GO:0120183"(positive regulation of focal adhesion disassembly)|go:"GO:1990782"(protein tyrosine kinase binding)|interpro:IPR000340(Protein-tyrosine phosphatase, dual specificity)|interpro:IPR000387(Protein-tyrosine phosphatase)|interpro:IPR016130(Protein-tyrosine phosphatase, active site)|interpro:IPR020405|interpro:IPR020422|interpro:IPR029021|mint:Q9D7X3|reactome:R-MMU-202670|go:"GO:1990264"(peptidyl-tyrosine dephosphorylation involved in inactivation of protein kinase activity)	-	chain-seq-start:60|chain-seq-end:166	comment:mint|function:This protein shows activity both toward tyrosine-protein phosphate as well as with serine-protein phosphate	figure legend:ST1.2|comment:DTT-eluted fraction|dataset:Rare diseases - Interactions investigated in the context of Rare genetic disease|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2020/12/04	2020/12/21	rogid:mvYK6+YgIN/WuGLBCWqsqPLfDyQ10090	rogid:CPkFDe9SCv4Nq8Dwl5NRteIKckg10090	rigid:sUlyHN3eQirg+yWIik/3UpGEVS4	false	mutation:34-34	-	-	-	psi-mi:"MI:0082"(peptide massfingerprinting)	psi-mi:"MI:0082"(peptide massfingerprinting)
uniprotkb:P97493-PRO_0000034151	uniprotkb:Q8K354	intact:EBI-26567598	intact:EBI-8321969|intact:MINT-4117620|ensembl:ENSMUSP00000047712	psi-mi:p97493-pro_0000034151(display_long)|uniprotkb:Thioredoxin-2(gene name synonym)|uniprotkb:Txn2(gene name)|psi-mi:Txn2(display_short)	psi-mi:cbr3_mouse(display_long)|uniprotkb:Cbr3(gene name)|psi-mi:Cbr3(display_short)|uniprotkb:NADPH-dependent carbonyl reductase 3(gene name synonym)	psi-mi:"MI:0096"(pull down)	Chasapis et al. (2019)	pubmed:31018154|imex:IM-28571	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26499997|imex:IM-28571-41	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	intact:EBI-8354432(chain-parent)	refseq:NP_766635.1|ensembl:ENSMUSG00000022947(gene)|ensembl:ENSMUST00000039620(transcript)|go:"GO:0000253"(3-keto sterol reductase activity)|go:"GO:0004090"("carbonyl reductase (NADPH) activity")|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0042376"(phylloquinone catabolic process)|go:"GO:0050890"(cognition)|go:"GO:0070402"(NADPH binding)|interpro:IPR002347(Glucose/ribitol dehydrogenase)|interpro:IPR020904|interpro:IPR036291|mint:Q8K354|reactome:R-MMU-211945	-	chain-seq-start:60|chain-seq-end:166	comment:mint	figure legend:ST1.2|comment:DTT-eluted fraction|dataset:Rare diseases - Interactions investigated in the context of Rare genetic disease|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2020/12/04	2020/12/21	rogid:mvYK6+YgIN/WuGLBCWqsqPLfDyQ10090	rogid:7MDBEB8lGtUcG+neZ3a6Ed59foM10090	rigid:sUlyHN3eQirg+yWIik/3UpGEVS4	false	mutation:34-34	-	-	-	psi-mi:"MI:0082"(peptide massfingerprinting)	psi-mi:"MI:0082"(peptide massfingerprinting)
uniprotkb:P97493-PRO_0000034151	uniprotkb:Q08093	intact:EBI-26567598	intact:EBI-8369968|intact:MINT-4091098|ensembl:ENSMUSP00000004784	psi-mi:p97493-pro_0000034151(display_long)|uniprotkb:Thioredoxin-2(gene name synonym)|uniprotkb:Txn2(gene name)|psi-mi:Txn2(display_short)	psi-mi:cnn2_mouse(display_long)|uniprotkb:Cnn2(gene name)|psi-mi:Cnn2(display_short)|uniprotkb:Calponin H2, smooth muscle(gene name synonym)|uniprotkb:Neutral calponin(gene name synonym)	psi-mi:"MI:0096"(pull down)	Chasapis et al. (2019)	pubmed:31018154|imex:IM-28571	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26499997|imex:IM-28571-41	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	intact:EBI-8354432(chain-parent)	refseq:NP_031751.1|ensembl:ENSMUSG00000004665(gene)|ensembl:ENSMUST00000004784(transcript)|go:"GO:0001725"(stress fiber)|go:"GO:0003779"(actin binding)|go:"GO:0005516"(calmodulin binding)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0030097"(hemopoiesis)|go:"GO:0030336"(negative regulation of cell migration)|go:"GO:0031032"(actomyosin structure organization)|go:"GO:0032970"(regulation of actin filament-based process)|go:"GO:0042060"(wound healing)|go:"GO:0042127"(regulation of cell population proliferation)|go:"GO:0050765"(negative regulation of phagocytosis)|go:"GO:0071260"(cellular response to mechanical stimulus)|interpro:IPR000557(Calponin repeat)|interpro:IPR001715(Calponin-like actin-binding)|interpro:IPR001997(Calponin)|interpro:IPR003096(SM22/calponin)|interpro:IPR029974|interpro:IPR036872|mint:Q08093|reactome:R-MMU-6798695	-	chain-seq-start:60|chain-seq-end:166	function:Thin filament-associated protein that is implicated in the regulation and modulation of smooth muscle contraction. It is capable of binding to actin, calmodulin, troponin C and tropomyosin. The interaction of calponin with actin inhibits the actomyosin Mg-ATPase activity|comment:mint	figure legend:ST1.2|comment:DTT-eluted fraction|dataset:Rare diseases - Interactions investigated in the context of Rare genetic disease|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2020/12/04	2020/12/21	rogid:mvYK6+YgIN/WuGLBCWqsqPLfDyQ10090	rogid:QsppTYzOkWMrjF47k9xF3vbYFVQ10090	rigid:sUlyHN3eQirg+yWIik/3UpGEVS4	false	mutation:34-34	-	-	-	psi-mi:"MI:0082"(peptide massfingerprinting)	psi-mi:"MI:0082"(peptide massfingerprinting)
uniprotkb:P97493-PRO_0000034151	uniprotkb:P58871	intact:EBI-26567598	intact:EBI-8400054|uniprotkb:A2BH84|intact:MINT-4137005|uniprotkb:Q6ZPI8|ensembl:ENSMUSP00000107232	psi-mi:p97493-pro_0000034151(display_long)|uniprotkb:Thioredoxin-2(gene name synonym)|uniprotkb:Txn2(gene name)|psi-mi:Txn2(display_short)	psi-mi:tb182_mouse(display_long)|uniprotkb:Tnks1bp1(gene name)|psi-mi:Tnks1bp1(display_short)|uniprotkb:Tab182(gene name synonym)|uniprotkb:Kiaa1741(gene name synonym)	psi-mi:"MI:0096"(pull down)	Chasapis et al. (2019)	pubmed:31018154|imex:IM-28571	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26499997|imex:IM-28571-41	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	intact:EBI-8354432(chain-parent)	refseq:NP_001074729.1|refseq:XP_017173105.1|ensembl:ENSMUSG00000033955(gene)|ensembl:ENSMUST00000111605(transcript)|go:"GO:0000792"(heterochromatin)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0005912"(adherens junction)|go:"GO:0006302"(double-strand break repair)|go:"GO:0010800"(positive regulation of peptidyl-threonine phosphorylation)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0019899"(enzyme binding)|go:"GO:0030014"(CCR4-NOT complex)|go:"GO:0031954"(positive regulation of protein autophosphorylation)|go:"GO:0033138"(positive regulation of peptidyl-serine phosphorylation)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0071479"(cellular response to ionizing radiation)|go:"GO:0071532"(ankyrin repeat binding)|interpro:IPR032764|interpro:IPR040006|mint:P58871|reactome:R-MMU-429947|reactome:R-MMU-6804115	-	chain-seq-start:60|chain-seq-end:166	comment:mint	figure legend:ST1.2|comment:DTT-eluted fraction|dataset:Rare diseases - Interactions investigated in the context of Rare genetic disease|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2020/12/04	2020/12/21	rogid:mvYK6+YgIN/WuGLBCWqsqPLfDyQ10090	rogid:fRfsW/fpdOeuX/17jeteOhNX0Xs10090	rigid:sUlyHN3eQirg+yWIik/3UpGEVS4	false	mutation:34-34	-	-	-	psi-mi:"MI:0082"(peptide massfingerprinting)	psi-mi:"MI:0082"(peptide massfingerprinting)
uniprotkb:P97493-PRO_0000034151	uniprotkb:P51125	intact:EBI-26567598	intact:EBI-774331|uniprotkb:Q9EQV4|uniprotkb:Q9EQV5|uniprotkb:Q9QXQ3|uniprotkb:Q9QXQ4|uniprotkb:Q9R0N1|ensembl:ENSMUSP00000152174	psi-mi:p97493-pro_0000034151(display_long)|uniprotkb:Thioredoxin-2(gene name synonym)|uniprotkb:Txn2(gene name)|psi-mi:Txn2(display_short)	psi-mi:ical_mouse(display_long)|uniprotkb:Calpain inhibitor(gene name synonym)|uniprotkb:Cast(gene name)|psi-mi:Cast(display_short)	psi-mi:"MI:0096"(pull down)	Chasapis et al. (2019)	pubmed:31018154|imex:IM-28571	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26499997|imex:IM-28571-41	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	intact:EBI-8354432(chain-parent)	refseq:NP_001288082.1|refseq:NP_001288089.1|refseq:NP_001288110.1|refseq:XP_006517122.1|refseq:XP_011242768.1|refseq:XP_011242769.1|ensembl:ENSMUSG00000021585(gene)|ensembl:ENSMUST00000223206(transcript)|go:"GO:0002020"(protease binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005829"(cytosol)|go:"GO:0007343"(egg activation)|go:"GO:0010466"(negative regulation of peptidase activity)|go:"GO:0010859"(calcium-dependent cysteine-type endopeptidase inhibitor activity)|go:"GO:0014069"(postsynaptic density)|go:"GO:0016020"(membrane)|go:"GO:0030163"(protein catabolic process)|go:"GO:0043086"(negative regulation of catalytic activity)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0097340"(inhibition of cysteine-type endopeptidase activity)|go:"GO:2000675"(negative regulation of type B pancreatic cell apoptotic process)|interpro:IPR001259(Proteinase inhibitor I27, calpastatin)|interpro:IPR026998|mint:P51125|reactome:R-MMU-1474228	-	chain-seq-start:60|chain-seq-end:166	-	figure legend:ST1.2|comment:DTT-eluted fraction|dataset:Rare diseases - Interactions investigated in the context of Rare genetic disease|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2020/12/04	2020/12/21	rogid:mvYK6+YgIN/WuGLBCWqsqPLfDyQ10090	rogid:5CgHHYcW4TDDFmVinyL2WkytAZs10090	rigid:sUlyHN3eQirg+yWIik/3UpGEVS4	false	mutation:34-34	-	-	-	psi-mi:"MI:0082"(peptide massfingerprinting)	psi-mi:"MI:0082"(peptide massfingerprinting)
uniprotkb:P97493-PRO_0000034151	uniprotkb:Q8VCQ8	intact:EBI-26567598	intact:EBI-4282687|ensembl:ENSMUSP00000110673	psi-mi:p97493-pro_0000034151(display_long)|uniprotkb:Thioredoxin-2(gene name synonym)|uniprotkb:Txn2(gene name)|psi-mi:Txn2(display_short)	psi-mi:q8vcq8_mouse(display_long)|uniprotkb:Cald1(gene name)|psi-mi:Cald1(display_short)	psi-mi:"MI:0096"(pull down)	Chasapis et al. (2019)	pubmed:31018154|imex:IM-28571	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26499997|imex:IM-28571-41	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	intact:EBI-8354432(chain-parent)	ensembl:ENSMUSG00000029761(gene)|ensembl:ENSMUST00000115021(transcript)|go:"GO:0001525"(angiogenesis)|go:"GO:0003779"(actin binding)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005884"(actin filament)|go:"GO:0006936"(muscle contraction)|go:"GO:0006940"(regulation of smooth muscle contraction)|go:"GO:0014069"(postsynaptic density)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0016020"(membrane)|go:"GO:0017022"(myosin binding)|go:"GO:0030425"(dendrite)|go:"GO:0030478"(actin cap)|go:"GO:0032092"(positive regulation of protein binding)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043197"(dendritic spine)|go:"GO:0051017"(actin filament bundle assembly)|interpro:IPR006017(Caldesmon)|interpro:IPR006018(Caldesmon and lymphocyte specific protein)|mint:Q8VCQ8|refseq:NP_663550.1	-	chain-seq-start:60|chain-seq-end:166	-	figure legend:ST1.2|comment:DTT-eluted fraction|dataset:Rare diseases - Interactions investigated in the context of Rare genetic disease|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2020/12/04	2020/12/21	rogid:mvYK6+YgIN/WuGLBCWqsqPLfDyQ10090	rogid:gFJMtF7/sH5eiLlx5zT2gpt4XVo10090	rigid:sUlyHN3eQirg+yWIik/3UpGEVS4	false	mutation:34-34	-	-	-	psi-mi:"MI:0082"(peptide massfingerprinting)	psi-mi:"MI:0082"(peptide massfingerprinting)
uniprotkb:P97493-PRO_0000034151	uniprotkb:P07356	intact:EBI-26567598	intact:EBI-738510|ensembl:ENSMUSP00000034756	psi-mi:p97493-pro_0000034151(display_long)|uniprotkb:Thioredoxin-2(gene name synonym)|uniprotkb:Txn2(gene name)|psi-mi:Txn2(display_short)	psi-mi:anxa2_mouse(display_long)|uniprotkb:Anxa2(gene name)|psi-mi:Anxa2(display_short)|uniprotkb:Anx2(gene name synonym)|uniprotkb:Cal1h(gene name synonym)|uniprotkb:Annexin-2(gene name synonym)|uniprotkb:Annexin II(gene name synonym)|uniprotkb:Lipocortin II(gene name synonym)|uniprotkb:Calpactin I heavy chain(gene name synonym)|uniprotkb:Chromobindin-8(gene name synonym)|uniprotkb:p36(gene name synonym)|uniprotkb:Protein I(gene name synonym)|uniprotkb:Placental anticoagulant protein IV(gene name synonym)|uniprotkb:Calpactin-1 heavy chain(gene name synonym)	psi-mi:"MI:0096"(pull down)	Chasapis et al. (2019)	pubmed:31018154|imex:IM-28571	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26499997|imex:IM-28571-41	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	intact:EBI-8354432(chain-parent)	refseq:NP_031611.1|refseq:XP_006510859.1|ensembl:ENSMUSG00000032231(gene)|ensembl:ENSMUST00000034756(transcript)|go:"GO:0001525"(angiogenesis)|go:"GO:0001726"(ruffle)|go:"GO:0001765"(membrane raft assembly)|go:"GO:0001786"(phosphatidylserine binding)|go:"GO:0001921"(positive regulation of receptor recycling)|go:"GO:0001934"(positive regulation of protein phosphorylation)|go:"GO:0002020"(protease binding)|go:"GO:0004867"(serine-type endopeptidase inhibitor activity)|go:"GO:0005262"(calcium channel activity)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005544"(calcium-dependent phospholipid binding)|go:"GO:0005546"(phosphatidylinositol-4,5-bisphosphate binding)|go:"GO:0005604"(basement membrane)|go:"GO:0005615"(extracellular space)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005768"(endosome)|go:"GO:0005769"(early endosome)|go:"GO:0005811"(lipid droplet)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005938"(cell cortex)|go:"GO:0006900"(vesicle budding from membrane)|go:"GO:0007589"(body fluid secretion)|go:"GO:0008092"(cytoskeletal protein binding)|go:"GO:0009986"(cell surface)|go:"GO:0016020"(membrane)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0019834"(phospholipase A2 inhibitor activity)|go:"GO:0019897"(extrinsic component of plasma membrane)|go:"GO:0030199"(collagen fibril organization)|go:"GO:0030496"(midbody)|go:"GO:0031267"(small GTPase binding)|go:"GO:0031340"(positive regulation of vesicle fusion)|go:"GO:0031902"(late endosome membrane)|go:"GO:0031982"(vesicle)|go:"GO:0032804"(negative regulation of low-density lipoprotein particle receptor catabolic process)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035749"(myelin sheath adaxonal region)|go:"GO:0036035"(osteoclast development)|go:"GO:0042383"(sarcolemma)|go:"GO:0042470"(melanosome)|go:"GO:0042730"(fibrinolysis)|go:"GO:0042802"(identical protein binding)|go:"GO:0043220"(Schmidt-Lanterman incisure)|go:"GO:0044090"(positive regulation of vacuole organization)|go:"GO:0044147"(negative regulation of formation of structure involved in a symbiotic process)|go:"GO:0044354"(macropinosome)|go:"GO:0044548"(S100 protein binding)|go:"GO:0044730"(bone sialoprotein binding)|go:"GO:0045121"(membrane raft)|go:"GO:0046790"(virion binding)|go:"GO:0048146"(positive regulation of fibroblast proliferation)|go:"GO:0048306"(calcium-dependent protein binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051099"(positive regulation of binding)|go:"GO:0052362"(obsolete catabolism by host of symbiont protein)|go:"GO:0052405"|go:"GO:0062023"(collagen-containing extracellular matrix)|go:"GO:0070062"(extracellular exosome)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0097066"(response to thyroid hormone)|go:"GO:1905581"(positive regulation of low-density lipoprotein particle clearance)|go:"GO:1905597"(positive regulation of low-density lipoprotein particle receptor binding)|go:"GO:1905599"(positive regulation of low-density lipoprotein receptor activity)|go:"GO:1905602"(positive regulation of receptor-mediated endocytosis involved in cholesterol transport)|go:"GO:1990665"(AnxA2-p11 complex)|go:"GO:1990667"(PCSK9-AnxA2 complex)|interpro:IPR001464(Annexin)|interpro:IPR002389(Annexin, type II)|interpro:IPR018252|interpro:IPR018502|interpro:IPR037104|mint:P07356|rcsb pdb:4HRE|reactome:R-MMU-6798695|reactome:R-MMU-75205	-	chain-seq-start:60|chain-seq-end:166	-	figure legend:ST1.2|comment:DTT-eluted fraction|dataset:Rare diseases - Interactions investigated in the context of Rare genetic disease|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2020/12/04	2020/12/21	rogid:mvYK6+YgIN/WuGLBCWqsqPLfDyQ10090	rogid:R7GyK+r4KmwX28VH2qQZF+Y729A10090	rigid:sUlyHN3eQirg+yWIik/3UpGEVS4	false	mutation:34-34	-	-	-	psi-mi:"MI:0082"(peptide massfingerprinting)	psi-mi:"MI:0082"(peptide massfingerprinting)
uniprotkb:P97493-PRO_0000034151	uniprotkb:P17182	intact:EBI-26567598	intact:EBI-299507|ensembl:ENSMUSP00000075513|ensembl:ENSMUSP00000079727|ensembl:ENSMUSP00000157807|uniprotkb:Q99KT7|uniprotkb:Q9DCY7	psi-mi:p97493-pro_0000034151(display_long)|uniprotkb:Thioredoxin-2(gene name synonym)|uniprotkb:Txn2(gene name)|psi-mi:Txn2(display_short)	psi-mi:enoa_mouse(display_long)|uniprotkb:Eno1(gene name)|psi-mi:Eno1(display_short)|uniprotkb:Eno-1(gene name synonym)|uniprotkb:2-phospho-D-glycerate hydro-lyase(gene name synonym)|uniprotkb:Non-neural enolase(gene name synonym)|uniprotkb:Enolase 1(gene name synonym)	psi-mi:"MI:0096"(pull down)	Chasapis et al. (2019)	pubmed:31018154|imex:IM-28571	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26499997|imex:IM-28571-41	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	intact:EBI-8354432(chain-parent)	ensembl:ENSMUSG00000059040(gene)|ensembl:ENSMUSG00000063524(gene)|ensembl:ENSMUST00000076155(transcript)|ensembl:ENSMUST00000080926(transcript)|ensembl:ENSMUST00000235307(transcript)|go:"GO:0000015"(phosphopyruvate hydratase complex)|go:"GO:0000287"(magnesium ion binding)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0003723"(RNA binding)|go:"GO:0004634"(phosphopyruvate hydratase activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006096"(glycolytic process)|go:"GO:0009986"(cell surface)|go:"GO:0016020"(membrane)|go:"GO:0019897"(extrinsic component of plasma membrane)|go:"GO:0019899"(enzyme binding)|go:"GO:0030426"(growth cone)|go:"GO:0032889"(regulation of vacuole fusion, non-autophagic)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043005"(neuron projection)|go:"GO:0043209"(myelin sheath)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045121"(membrane raft)|go:"GO:0051020"(GTPase binding)|go:"GO:0031072"(heat shock protein binding)|go:"GO:0051099"(positive regulation of binding)|go:"GO:0061621"(canonical glycolysis)|go:"GO:0097060"(synaptic membrane)|go:"GO:0098761"(cellular response to interleukin-7)|go:"GO:0099738"(cell cortex region)|interpro:IPR000941(Enolase)|interpro:IPR020809|interpro:IPR020810|interpro:IPR020811|interpro:IPR029017|interpro:IPR036849|mint:P17182|reactome:R-MMU-70171|reactome:R-MMU-70263|refseq:NP_001020559.1|refseq:NP_075608.2|refseq:XP_006538588.2	-	chain-seq-start:60|chain-seq-end:166	-	figure legend:ST1.2|comment:DTT-eluted fraction|dataset:Rare diseases - Interactions investigated in the context of Rare genetic disease|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2020/12/04	2020/12/21	rogid:mvYK6+YgIN/WuGLBCWqsqPLfDyQ10090	rogid:YFpn/7GDB6vXgCYLSxvNns7FlT410090	rigid:sUlyHN3eQirg+yWIik/3UpGEVS4	false	mutation:34-34	-	-	-	psi-mi:"MI:0082"(peptide massfingerprinting)	psi-mi:"MI:0082"(peptide massfingerprinting)
uniprotkb:P97493-PRO_0000034151	uniprotkb:O54931	intact:EBI-26567598	intact:EBI-645808|uniprotkb:O54932|uniprotkb:O54933|uniprotkb:A2APJ4|uniprotkb:Q8C5W1|ensembl:ENSMUSP00000048678	psi-mi:p97493-pro_0000034151(display_long)|uniprotkb:Thioredoxin-2(gene name synonym)|uniprotkb:Txn2(gene name)|psi-mi:Txn2(display_short)	psi-mi:akap2_mouse(display_long)|uniprotkb:Protein kinase A-anchoring protein 2(gene name synonym)|uniprotkb:AKAP expressed in kidney and lung(gene name synonym)|uniprotkb:Akap2(gene name)|psi-mi:Akap2(display_short)	psi-mi:"MI:0096"(pull down)	Chasapis et al. (2019)	pubmed:31018154|imex:IM-28571	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26499997|imex:IM-28571-41	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	intact:EBI-8354432(chain-parent)	refseq:NP_001030609.1|refseq:NP_001030610.1|refseq:NP_001291473.1|ensembl:ENSMUSG00000038729(gene)|ensembl:ENSMUST00000043456(transcript)|interpro:IPR029304|mint:O54931	-	chain-seq-start:60|chain-seq-end:166	-	figure legend:ST1.2|comment:DTT-eluted fraction|dataset:Rare diseases - Interactions investigated in the context of Rare genetic disease|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2020/12/04	2020/12/21	rogid:mvYK6+YgIN/WuGLBCWqsqPLfDyQ10090	rogid:DG3cb//yT74MSVq4CBV7z/m95Nw10090	rigid:sUlyHN3eQirg+yWIik/3UpGEVS4	false	mutation:34-34	-	-	-	psi-mi:"MI:0082"(peptide massfingerprinting)	psi-mi:"MI:0082"(peptide massfingerprinting)
uniprotkb:P97493-PRO_0000034151	uniprotkb:P20152	intact:EBI-26567598	intact:EBI-299269|ensembl:ENSMUSP00000028062|uniprotkb:O08704|uniprotkb:Q8CCH1	psi-mi:p97493-pro_0000034151(display_long)|uniprotkb:Thioredoxin-2(gene name synonym)|uniprotkb:Txn2(gene name)|psi-mi:Txn2(display_short)	psi-mi:vime_mouse(display_long)|uniprotkb:Vim(gene name)|psi-mi:Vim(display_short)	psi-mi:"MI:0096"(pull down)	Chasapis et al. (2019)	pubmed:31018154|imex:IM-28571	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26499997|imex:IM-28571-41	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	intact:EBI-8354432(chain-parent)	ensembl:ENSMUSG00000026728(gene)|ensembl:ENSMUST00000028062(transcript)|go:"GO:0003725"(double-stranded RNA binding)|go:"GO:0005200"(structural constituent of cytoskeleton)|go:"GO:0005212"(structural constituent of eye lens)|go:"GO:0005737"(cytoplasm)|go:"GO:0005777"(peroxisome)|go:"GO:0005829"(cytosol)|go:"GO:0005844"(polysome)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005882"(intermediate filament)|go:"GO:0005886"(plasma membrane)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010977"(negative regulation of neuron projection development)|go:"GO:0014002"(astrocyte development)|go:"GO:0016363"(nuclear matrix)|go:"GO:0045109"(intermediate filament organization)|go:"GO:0045111"(intermediate filament cytoskeleton)|go:"GO:0045335"(phagocytic vesicle)|go:"GO:0045727"(positive regulation of translation)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0050770"(regulation of axonogenesis)|go:"GO:0051721"(protein phosphatase 2A binding)|go:"GO:0019900"(kinase binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0060020"(Bergmann glial cell differentiation)|go:"GO:0060252"(positive regulation of glial cell proliferation)|go:"GO:0060395"(SMAD protein signal transduction)|go:"GO:0070307"(lens fiber cell development)|go:"GO:0071222"(cellular response to lipopolysaccharide)|go:"GO:0071225"(cellular response to muramyl dipeptide)|go:"GO:0071346"(cellular response to interferon-gamma)|go:"GO:0097110"(scaffold protein binding)|go:"GO:1900147"(regulation of Schwann cell migration)|go:"GO:1990254"(keratin filament binding)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR006821(Intermediate filament, DNA-binding region)|interpro:IPR018039|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030424"(axon)|go:"GO:0031252"(cell leading edge)|interpro:IPR027699|interpro:IPR039008|mint:P20152|reactome:R-MMU-264870|reactome:R-MMU-390522|reactome:R-MMU-9013422|go:"GO:0032967"(positive regulation of collagen biosynthetic process)|reactome:R-MMU-9646399|go:"GO:0042802"(identical protein binding)|go:"GO:0042995"(cell projection)|go:"GO:0043005"(neuron projection)|go:"GO:0043488"(regulation of mRNA stability)|go:"GO:0044297"(cell body)|go:"GO:0045098"(type III intermediate filament)|go:"GO:0045103"(intermediate filament-based process)|refseq:NP_035831.2|dip:DIP-188N	-	chain-seq-start:60|chain-seq-end:166	-	figure legend:ST1.2|comment:DTT-eluted fraction|dataset:Rare diseases - Interactions investigated in the context of Rare genetic disease|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2020/12/04	2020/12/21	rogid:mvYK6+YgIN/WuGLBCWqsqPLfDyQ10090	rogid://GDvGAXOR4hUXNtVpnZefex5v410090	rigid:sUlyHN3eQirg+yWIik/3UpGEVS4	false	mutation:34-34	-	-	-	psi-mi:"MI:0082"(peptide massfingerprinting)	psi-mi:"MI:0082"(peptide massfingerprinting)
uniprotkb:P97493-PRO_0000034151	uniprotkb:Q8C3W1	intact:EBI-26567598	intact:EBI-26499336|ensembl:ENSMUSP00000034464|uniprotkb:Q3TCS2|uniprotkb:Q3U2K7|uniprotkb:Q3U3E1|uniprotkb:Q6PDM3	psi-mi:p97493-pro_0000034151(display_long)|uniprotkb:Thioredoxin-2(gene name synonym)|uniprotkb:Txn2(gene name)|psi-mi:Txn2(display_short)	psi-mi:ca198_mouse(display_long)	psi-mi:"MI:0096"(pull down)	Chasapis et al. (2019)	pubmed:31018154|imex:IM-28571	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26499997|imex:IM-28571-41	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	intact:EBI-8354432(chain-parent)	ensembl:ENSMUSG00000031983(gene)|ensembl:ENSMUST00000034464(transcript)|go:"GO:0005829"(cytosol)|interpro:IPR031600|mint:Q8C3W1|refseq:NP_780358.3	-	chain-seq-start:60|chain-seq-end:166	-	figure legend:ST1.2|comment:DTT-eluted fraction|dataset:Rare diseases - Interactions investigated in the context of Rare genetic disease|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2020/12/04	2020/12/21	rogid:mvYK6+YgIN/WuGLBCWqsqPLfDyQ10090	rogid:pNMuHeiesPcL3JRWFQUZ6fPAzI810090	rigid:sUlyHN3eQirg+yWIik/3UpGEVS4	false	mutation:34-34	-	-	-	psi-mi:"MI:0082"(peptide massfingerprinting)	psi-mi:"MI:0082"(peptide massfingerprinting)
uniprotkb:P97493-PRO_0000034151	uniprotkb:P26039	intact:EBI-26567598	intact:EBI-1039593|uniprotkb:Q8VEF0|uniprotkb:A2AIM8|ensembl:ENSMUSP00000030187	psi-mi:p97493-pro_0000034151(display_long)|uniprotkb:Thioredoxin-2(gene name synonym)|uniprotkb:Txn2(gene name)|psi-mi:Txn2(display_short)	psi-mi:tln1_mouse(display_long)|uniprotkb:Tln1(gene name)|psi-mi:Tln1(display_short)|uniprotkb:Tln(gene name synonym)	psi-mi:"MI:0096"(pull down)	Chasapis et al. (2019)	pubmed:31018154|imex:IM-28571	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26499997|imex:IM-28571-41	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	intact:EBI-8354432(chain-parent)	refseq:NP_035732.2|refseq:XP_006537832.2|ensembl:ENSMUSG00000028465(gene)|ensembl:ENSMUST00000030187(transcript)|go:"GO:0001726"(ruffle)|go:"GO:0001786"(phosphatidylserine binding)|go:"GO:0005178"(integrin binding)|go:"GO:0005200"(structural constituent of cytoskeleton)|go:"GO:0005737"(cytoplasm)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005886"(plasma membrane)|go:"GO:0005912"(adherens junction)|go:"GO:0005925"(focal adhesion)|go:"GO:0007044"(cell-substrate junction assembly)|go:"GO:0007229"(integrin-mediated signaling pathway)|go:"GO:0009986"(cell surface)|go:"GO:0017166"(vinculin binding)|go:"GO:0030274"(LIM domain binding)|go:"GO:0030866"(cortical actin cytoskeleton organization)|go:"GO:0032587"(ruffle membrane)|go:"GO:0033622"(integrin activation)|go:"GO:0035091"(phosphatidylinositol binding)|go:"GO:0051015"(actin filament binding)|go:"GO:0098609"(cell-cell adhesion)|interpro:IPR000299(Band 4.1, N-terminal)|interpro:IPR002558(I/LWEQ)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR014352(FERM/acyl-CoA-binding protein, 3-helical bundle)|interpro:IPR015009(Vinculin Binding Site)|interpro:IPR015224(Talin, central)|interpro:IPR019747|interpro:IPR019748|interpro:IPR019749|interpro:IPR029071|interpro:IPR032425|interpro:IPR035963|interpro:IPR035964|interpro:IPR036476|interpro:IPR036723|interpro:IPR037438|mint:P26039|rcsb pdb:1SJ7|rcsb pdb:1SJ8|rcsb pdb:1T01|rcsb pdb:1U89|rcsb pdb:1XWX|rcsb pdb:1Y19|rcsb pdb:1ZW3|rcsb pdb:2B0H|rcsb pdb:2G35|rcsb pdb:2JSW|rcsb pdb:2KBB|rcsb pdb:2KC1|rcsb pdb:2KC2|rcsb pdb:2KGX|rcsb pdb:2KMA|rcsb pdb:2KVP|rcsb pdb:2L10|rcsb pdb:2L7A|rcsb pdb:2L7N|rcsb pdb:2LQG|rcsb pdb:2QDQ|rcsb pdb:2X0C|rcsb pdb:3DYJ|rcsb pdb:3IVF|rcsb pdb:3S90|rcsb pdb:4F7G|rcsb pdb:4W8P|rcsb pdb:5FZT|rcsb pdb:5IC0|rcsb pdb:5IC1|rcsb pdb:5NL1|rcsb pdb:6BA6|rcsb pdb:6MFS|rcsb pdb:6TWN|rcsb pdb:6VGU|reactome:R-MMU-114608|reactome:R-MMU-354192|reactome:R-MMU-354194|reactome:R-MMU-372708|reactome:R-MMU-399955|reactome:R-MMU-445355|reactome:R-MMU-5674135|dip:DIP-647N	-	chain-seq-start:60|chain-seq-end:166	-	figure legend:ST1.2|comment:DTT-eluted fraction|dataset:Rare diseases - Interactions investigated in the context of Rare genetic disease|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2020/12/04	2020/12/21	rogid:mvYK6+YgIN/WuGLBCWqsqPLfDyQ10090	rogid:w9NQrwqUcuVAzeesymnTmhrEtCk10090	rigid:sUlyHN3eQirg+yWIik/3UpGEVS4	false	mutation:34-34	-	-	-	psi-mi:"MI:0082"(peptide massfingerprinting)	psi-mi:"MI:0082"(peptide massfingerprinting)
uniprotkb:P97493-PRO_0000034151	uniprotkb:Q9D5V6	intact:EBI-26567598	intact:EBI-26499304|ensembl:ENSMUSP00000033723|uniprotkb:Q3UI67|uniprotkb:Q9D870	psi-mi:p97493-pro_0000034151(display_long)|uniprotkb:Thioredoxin-2(gene name synonym)|uniprotkb:Txn2(gene name)|psi-mi:Txn2(display_short)	psi-mi:syap1_mouse(display_long)|uniprotkb:Syap1(gene name)|psi-mi:Syap1(display_short)|uniprotkb:BSD domain-containing signal transducer and Akt interactor protein(gene name synonym)	psi-mi:"MI:0096"(pull down)	Chasapis et al. (2019)	pubmed:31018154|imex:IM-28571	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26499997|imex:IM-28571-41	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	intact:EBI-8354432(chain-parent)	ensembl:ENSMUSG00000031357(gene)|ensembl:ENSMUST00000033723(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0030154"(cell differentiation)|go:"GO:0030424"(axon)|go:"GO:0030425"(dendrite)|go:"GO:0030426"(growth cone)|go:"GO:0031234"(extrinsic component of cytoplasmic side of plasma membrane)|go:"GO:0032869"(cellular response to insulin stimulus)|go:"GO:0036120"(cellular response to platelet-derived growth factor stimulus)|go:"GO:0038203"(TORC2 signaling)|go:"GO:0042734"(presynaptic membrane)|go:"GO:0043204"(perikaryon)|go:"GO:0045211"(postsynaptic membrane)|go:"GO:0045600"(positive regulation of fat cell differentiation)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0071364"(cellular response to epidermal growth factor stimulus)|go:"GO:0071902"(positive regulation of protein serine/threonine kinase activity)|go:"GO:1990314"(cellular response to insulin-like growth factor stimulus)|interpro:IPR005607(BSD)|interpro:IPR035925|mint:Q9D5V6|refseq:NP_080208.2	-	chain-seq-start:60|chain-seq-end:166	-	figure legend:ST1.2|comment:DTT-eluted fraction|dataset:Rare diseases - Interactions investigated in the context of Rare genetic disease|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2020/12/04	2020/12/21	rogid:mvYK6+YgIN/WuGLBCWqsqPLfDyQ10090	rogid:46qN+WDDU6nJo/BWzvUndVAd5gg10090	rigid:sUlyHN3eQirg+yWIik/3UpGEVS4	false	mutation:34-34	-	-	-	psi-mi:"MI:0082"(peptide massfingerprinting)	psi-mi:"MI:0082"(peptide massfingerprinting)
uniprotkb:P97493-PRO_0000034151	uniprotkb:Q60864	intact:EBI-26567598	intact:EBI-494437|uniprotkb:Q3TT16|uniprotkb:Q8BPH3|uniprotkb:Q99L66|ensembl:ENSMUSP00000025918	psi-mi:p97493-pro_0000034151(display_long)|uniprotkb:Thioredoxin-2(gene name synonym)|uniprotkb:Txn2(gene name)|psi-mi:Txn2(display_short)	psi-mi:stip1_mouse(display_long)|uniprotkb:Hsc70/Hsp90-organizing protein(gene name synonym)|uniprotkb:Stip1(gene name)|psi-mi:Stip1(display_short)	psi-mi:"MI:0096"(pull down)	Chasapis et al. (2019)	pubmed:31018154|imex:IM-28571	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26499997|imex:IM-28571-41	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	intact:EBI-8354432(chain-parent)	refseq:NP_058017.1|ensembl:ENSMUSG00000024966(gene)|ensembl:ENSMUST00000025918(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0030544"(Hsp70 protein binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0043209"(myelin sheath)|go:"GO:0051087"(chaperone binding)|go:"GO:0051879"(Hsp90 protein binding)|go:"GO:0098761"(cellular response to interleukin-7)|go:"GO:0101031"(chaperone complex)|go:"GO:0120293"(dynein axonemal particle)|interpro:IPR001440(Tetratricopeptide TPR-1)|interpro:IPR006636(Heat shock chaperonin-binding)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR019734|interpro:IPR041243|mint:Q60864|reactome:R-MMU-3371497|reactome:R-MMU-9696273	-	chain-seq-start:60|chain-seq-end:166	-	figure legend:ST1.2|comment:DTT-eluted fraction|dataset:Rare diseases - Interactions investigated in the context of Rare genetic disease|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2020/12/04	2020/12/21	rogid:mvYK6+YgIN/WuGLBCWqsqPLfDyQ10090	rogid:f6DTvAcA6tKSLqzw11r9X+rC8ao10090	rigid:sUlyHN3eQirg+yWIik/3UpGEVS4	false	mutation:34-34	-	-	-	psi-mi:"MI:0082"(peptide massfingerprinting)	psi-mi:"MI:0082"(peptide massfingerprinting)
uniprotkb:P97493-PRO_0000034151	uniprotkb:Q60598	intact:EBI-26567598	intact:EBI-397955|intact:EBI-4281621|uniprotkb:Q3UGC2|ensembl:ENSMUSP00000099368	psi-mi:p97493-pro_0000034151(display_long)|uniprotkb:Thioredoxin-2(gene name synonym)|uniprotkb:Txn2(gene name)|psi-mi:Txn2(display_short)	psi-mi:src8_mouse(display_long)|uniprotkb:Cttn(gene name)|psi-mi:Cttn(display_short)|uniprotkb:Ems1(gene name synonym)	psi-mi:"MI:0096"(pull down)	Chasapis et al. (2019)	pubmed:31018154|imex:IM-28571	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26499997|imex:IM-28571-41	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	intact:EBI-8354432(chain-parent)	refseq:NP_031829.2|ensembl:ENSMUSG00000031078(gene)|ensembl:ENSMUST00000103079(transcript)|go:"GO:0001726"(ruffle)|go:"GO:0002102"(podosome)|go:"GO:0005522"(profilin binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0005884"(actin filament)|go:"GO:0005886"(plasma membrane)|go:"GO:0005905"(clathrin-coated pit)|go:"GO:0005925"(focal adhesion)|go:"GO:0005938"(cell cortex)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006898"(receptor-mediated endocytosis)|go:"GO:0006930"(substrate-dependent cell migration, cell extension)|go:"GO:0008076"(voltage-gated potassium channel complex)|go:"GO:0030027"(lamellipodium)|go:"GO:0030041"(actin filament polymerization)|go:"GO:0030054"(cell junction)|go:"GO:0030427"(site of polarized growth)|go:"GO:0030516"(regulation of axon extension)|go:"GO:0030833"(regulation of actin filament polymerization)|go:"GO:0030838"(positive regulation of actin filament polymerization)|go:"GO:1990023"(mitotic spindle midzone)|go:"GO:2001237"(negative regulation of extrinsic apoptotic signaling pathway)|interpro:IPR001452(Src homology-3)|interpro:IPR003134(Hs1/Cortactin)|interpro:IPR015503(Cortactin)|interpro:IPR035716|go:"GO:0030863"(cortical cytoskeleton)|go:"GO:0030864"(cortical actin cytoskeleton)|go:"GO:0031532"(actin cytoskeleton reorganization)|go:"GO:0043197"(dendritic spine)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0045987"(positive regulation of smooth muscle contraction)|go:"GO:0048041"(focal adhesion assembly)|go:"GO:0048812"(neuron projection morphogenesis)|go:"GO:0048870"(cell motility)|go:"GO:0050921"(positive regulation of chemotaxis)|go:"GO:0051015"(actin filament binding)|go:"GO:0060491"(regulation of cell projection assembly)|go:"GO:0070064"(proline-rich region binding)|go:"GO:0071933"(Arp2/3 complex binding)|go:"GO:0097062"(dendritic spine maintenance)|go:"GO:0097581"(lamellipodium organization)|go:"GO:0098871"(postsynaptic actin cytoskeleton)|go:"GO:0098885"(modification of postsynaptic actin cytoskeleton)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:1903146"(regulation of autophagy of mitochondrion)|interpro:IPR036028|mint:Q60598|rcsb pdb:2F9X|rcsb pdb:3ULR|rcsb pdb:5NV1|rcsb pdb:5NVJ|rcsb pdb:5NXJ|reactome:R-MMU-8856828|dip:DIP-31562N	-	chain-seq-start:60|chain-seq-end:166	-	figure legend:ST1.2|comment:DTT-eluted fraction|dataset:Rare diseases - Interactions investigated in the context of Rare genetic disease|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2020/12/04	2020/12/21	rogid:mvYK6+YgIN/WuGLBCWqsqPLfDyQ10090	rogid:4hLyMrquWdlJnIX2pHuXqYtQgkE10090	rigid:sUlyHN3eQirg+yWIik/3UpGEVS4	false	mutation:34-34	-	-	-	psi-mi:"MI:0082"(peptide massfingerprinting)	psi-mi:"MI:0082"(peptide massfingerprinting)
uniprotkb:P97493-PRO_0000034151	uniprotkb:Q8BRB8	intact:EBI-26567598	intact:EBI-26499280	psi-mi:p97493-pro_0000034151(display_long)|uniprotkb:Thioredoxin-2(gene name synonym)|uniprotkb:Txn2(gene name)|psi-mi:Txn2(display_short)	psi-mi:q8brb8_mouse(display_long)|uniprotkb:Ahnak(gene name)|psi-mi:Ahnak(display_short)	psi-mi:"MI:0096"(pull down)	Chasapis et al. (2019)	pubmed:31018154|imex:IM-28571	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26499997|imex:IM-28571-41	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	intact:EBI-8354432(chain-parent)	go:"GO:1901385"(regulation of voltage-gated calcium channel activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0031982"(vesicle)|go:"GO:0042383"(sarcolemma)|go:"GO:0042802"(identical protein binding)|go:"GO:0043034"(costamere)|go:"GO:0043484"(regulation of RNA splicing)|go:"GO:0044291"(cell-cell contact zone)|go:"GO:0044548"(S100 protein binding)|go:"GO:0070062"(extracellular exosome)|mint:Q8BRB8|refseq:NP_001035048.1|refseq:NP_001273447.1|refseq:NP_033773.1|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR036034	-	chain-seq-start:60|chain-seq-end:166	-	figure legend:ST1.2|comment:DTT-eluted fraction|dataset:Rare diseases - Interactions investigated in the context of Rare genetic disease|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2020/12/04	2020/12/21	rogid:mvYK6+YgIN/WuGLBCWqsqPLfDyQ10090	rogid:dTR5OsSePHgkYlpiMeEqO5ZnSCw10090	rigid:sUlyHN3eQirg+yWIik/3UpGEVS4	false	mutation:34-34	-	-	-	psi-mi:"MI:0082"(peptide massfingerprinting)	psi-mi:"MI:0082"(peptide massfingerprinting)
uniprotkb:P97493-PRO_0000034151	uniprotkb:P07724	intact:EBI-26567598	intact:EBI-1183810|uniprotkb:Q3TV03|uniprotkb:Q61802|uniprotkb:Q8C7C7|uniprotkb:Q8C7H3|uniprotkb:Q8CG74|ensembl:ENSMUSP00000031314	psi-mi:p97493-pro_0000034151(display_long)|uniprotkb:Thioredoxin-2(gene name synonym)|uniprotkb:Txn2(gene name)|psi-mi:Txn2(display_short)	psi-mi:albu_mouse(display_long)|uniprotkb:Alb(gene name)|psi-mi:Alb(display_short)|uniprotkb:Alb1(gene name synonym)|uniprotkb:Alb-1(gene name synonym)	psi-mi:"MI:0096"(pull down)	Chasapis et al. (2019)	pubmed:31018154|imex:IM-28571	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26499997|imex:IM-28571-41	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	intact:EBI-8354432(chain-parent)	refseq:NP_033784.2|ensembl:ENSMUSG00000029368(gene)|ensembl:ENSMUST00000031314(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0005504"(fatty acid binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005604"(basement membrane)|go:"GO:0005615"(extracellular space)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0008270"(zinc ion binding)|go:"GO:0009267"(cellular response to starvation)|go:"GO:0015643"(toxic substance binding)|go:"GO:0019825"(oxygen binding)|go:"GO:0019899"(enzyme binding)|go:"GO:0030170"(pyridoxal phosphate binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043209"(myelin sheath)|go:"GO:0046010"(positive regulation of circadian sleep/wake cycle, non-REM sleep)|go:"GO:0051087"(chaperone binding)|go:"GO:0051659"(maintenance of mitochondrion location)|go:"GO:0070062"(extracellular exosome)|go:"GO:0072341"(modified amino acid binding)|go:"GO:0140272"(exogenous protein binding)|go:"GO:1903981"(enterobactin binding)|interpro:IPR000264(Serum albumin)|interpro:IPR014760(Serum albumin, N-terminal)|interpro:IPR020857|interpro:IPR020858|interpro:IPR021177|mint:P07724|reactome:R-MMU-114608|reactome:R-MMU-159418|reactome:R-MMU-189451|reactome:R-MMU-189483|reactome:R-MMU-2168880|reactome:R-MMU-381426|reactome:R-MMU-879518|reactome:R-MMU-8957275|reactome:R-MMU-8964058|reactome:R-MMU-9707564	-	chain-seq-start:60|chain-seq-end:166	-	figure legend:ST1.2|comment:DTT-eluted fraction|dataset:Rare diseases - Interactions investigated in the context of Rare genetic disease|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2020/12/04	2020/12/21	rogid:mvYK6+YgIN/WuGLBCWqsqPLfDyQ10090	rogid:R7zO/mB332rAl8J+WrXfsHzjSYs10090	rigid:sUlyHN3eQirg+yWIik/3UpGEVS4	false	mutation:34-34	-	-	-	psi-mi:"MI:0082"(peptide massfingerprinting)	psi-mi:"MI:0082"(peptide massfingerprinting)
uniprotkb:P97493-PRO_0000034151	uniprotkb:P60335	intact:EBI-26567598	intact:EBI-309059|ensembl:ENSMUSP00000054863	psi-mi:p97493-pro_0000034151(display_long)|uniprotkb:Thioredoxin-2(gene name synonym)|uniprotkb:Txn2(gene name)|psi-mi:Txn2(display_short)	psi-mi:pcbp1_mouse(display_long)|uniprotkb:Pcbp1(gene name)|psi-mi:Pcbp1(display_short)|uniprotkb:Alpha-CP1(gene name synonym)|uniprotkb:Heterogeneous nuclear ribonucleoprotein E1(gene name synonym)	psi-mi:"MI:0096"(pull down)	Chasapis et al. (2019)	pubmed:31018154|imex:IM-28571	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26499997|imex:IM-28571-41	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	intact:EBI-8354432(chain-parent)	refseq:NP_035995.1|ensembl:ENSMUSG00000051695(gene)|ensembl:ENSMUST00000053015(transcript)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0003730"(mRNA 3'-UTR binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006397"(mRNA processing)|go:"GO:0008494"(translation activator activity)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0016607"(nuclear speck)|go:"GO:0036464"(cytoplasmic ribonucleoprotein granule)|go:"GO:0039694"(viral RNA genome replication)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0051252"(regulation of RNA metabolic process)|go:"GO:0098847"(sequence-specific single stranded DNA binding)|interpro:IPR004087(K Homology)|interpro:IPR004088(K Homology, type 1)|interpro:IPR036612|mint:P60335|reactome:R-MMU-72163|reactome:R-MMU-72203	-	chain-seq-start:60|chain-seq-end:166	-	figure legend:ST1.2|comment:DTT-eluted fraction|dataset:Rare diseases - Interactions investigated in the context of Rare genetic disease|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2020/12/04	2020/12/21	rogid:mvYK6+YgIN/WuGLBCWqsqPLfDyQ10090	rogid:x72fawo4plQ+ipfqIoREIDHc2bA10090	rigid:sUlyHN3eQirg+yWIik/3UpGEVS4	false	mutation:34-34	-	-	-	psi-mi:"MI:0082"(peptide massfingerprinting)	psi-mi:"MI:0082"(peptide massfingerprinting)
uniprotkb:P97493-PRO_0000034151	uniprotkb:O08709	intact:EBI-26567598	intact:EBI-444895|uniprotkb:Q91WT2|uniprotkb:Q9QWP4|uniprotkb:Q9QWW0	psi-mi:p97493-pro_0000034151(display_long)|uniprotkb:Thioredoxin-2(gene name synonym)|uniprotkb:Txn2(gene name)|psi-mi:Txn2(display_short)	psi-mi:prdx6_mouse(display_long)|uniprotkb:Lysophosphatidylcholine acyltransferase 5(gene name synonym)|uniprotkb:Glutathione-dependent peroxiredoxin(gene name synonym)|uniprotkb:Antioxidant protein 2(gene name synonym)|uniprotkb:1-Cys peroxiredoxin(gene name synonym)|uniprotkb:Acidic calcium-independent phospholipase A2(gene name synonym)|uniprotkb:Non-selenium glutathione peroxidase(gene name synonym)|uniprotkb:Prdx6(gene name)|psi-mi:Prdx6(display_short)|uniprotkb:Aop2(gene name synonym)|uniprotkb:Ltw4(gene name synonym)|uniprotkb:Prdx5(gene name synonym)	psi-mi:"MI:0096"(pull down)	Chasapis et al. (2019)	pubmed:31018154|imex:IM-28571	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26499997|imex:IM-28571-41	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	intact:EBI-8354432(chain-parent)	refseq:NP_031479.1|interpro:IPR000866(Alkyl hydroperoxide reductase/ Thiol specific antioxidant/ Mal allergen)|interpro:IPR024706|interpro:IPR019479|go:"GO:0000302"(response to reactive oxygen species)|go:"GO:0004601"(peroxidase activity)|go:"GO:0004602"(glutathione peroxidase activity)|go:"GO:0004623"(phospholipase A2 activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005764"(lysosome)|go:"GO:0005829"(cytosol)|go:"GO:0006979"(response to oxidative stress)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032060"(bleb assembly)|go:"GO:0042744"(hydrogen peroxide catabolic process)|go:"GO:0042802"(identical protein binding)|go:"GO:0045454"(cell redox homeostasis)|go:"GO:0046475"(glycerophospholipid catabolic process)|go:"GO:0047184"(1-acylglycerophosphocholine O-acyltransferase activity)|go:"GO:0047499"(calcium-independent phospholipase A2 activity)|go:"GO:0048026"(positive regulation of mRNA splicing, via spliceosome)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051920"(peroxiredoxin activity)|go:"GO:0098869"(cellular oxidant detoxification)|go:"GO:0102567"|go:"GO:0102568"|reactome:R-MMU-3299685|reactome:R-MMU-6798695|interpro:IPR013766(Thioredoxin domain)|mint:O08709|interpro:IPR036249	-	chain-seq-start:60|chain-seq-end:166	-	figure legend:ST1.2|comment:DTT-eluted fraction|dataset:Rare diseases - Interactions investigated in the context of Rare genetic disease|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2020/12/04	2020/12/21	rogid:mvYK6+YgIN/WuGLBCWqsqPLfDyQ10090	rogid:3Hnse2vkowtSGEobI2LJX6WrNl410090	rigid:sUlyHN3eQirg+yWIik/3UpGEVS4	false	mutation:34-34	-	-	-	psi-mi:"MI:0082"(peptide massfingerprinting)	psi-mi:"MI:0082"(peptide massfingerprinting)
uniprotkb:P97493-PRO_0000034151	uniprotkb:O08807	intact:EBI-26567598	intact:EBI-494652|uniprotkb:Q3U8E4|uniprotkb:B1AZS7|ensembl:ENSMUSP00000026328	psi-mi:p97493-pro_0000034151(display_long)|uniprotkb:Thioredoxin-2(gene name synonym)|uniprotkb:Txn2(gene name)|psi-mi:Txn2(display_short)	psi-mi:prdx4_mouse(display_long)|uniprotkb:Peroxiredoxin IV(gene name synonym)|uniprotkb:Thioredoxin peroxidase AO372(gene name synonym)|uniprotkb:Thioredoxin-dependent peroxide reductase A0372(gene name synonym)|uniprotkb:Antioxidant enzyme AOE372(gene name synonym)|uniprotkb:Thioredoxin-dependent peroxiredoxin 4(gene name synonym)|uniprotkb:Prdx4(gene name)|psi-mi:Prdx4(display_short)	psi-mi:"MI:0096"(pull down)	Chasapis et al. (2019)	pubmed:31018154|imex:IM-28571	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26499997|imex:IM-28571-41	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	intact:EBI-8354432(chain-parent)	refseq:NP_058044.1|refseq:NP_001300640.1|dip:DIP-34137N|ensembl:ENSMUSG00000025289(gene)|ensembl:ENSMUST00000026328(transcript)|go:"GO:0004601"(peroxidase activity)|go:"GO:0005615"(extracellular space)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005790"(smooth endoplasmic reticulum)|go:"GO:0005829"(cytosol)|go:"GO:0006979"(response to oxidative stress)|go:"GO:0007283"(spermatogenesis)|go:"GO:0008584"(male gonad development)|go:"GO:0018401"(peptidyl-proline hydroxylation to 4-hydroxy-L-proline)|go:"GO:0022417"(protein maturation by protein folding)|go:"GO:0030198"(extracellular matrix organization)|go:"GO:0042802"(identical protein binding)|go:"GO:0045454"(cell redox homeostasis)|go:"GO:0051920"(peroxiredoxin activity)|go:"GO:0072593"(reactive oxygen species metabolic process)|go:"GO:2000255"(negative regulation of male germ cell proliferation)|interpro:IPR000866(Alkyl hydroperoxide reductase/ Thiol specific antioxidant/ Mal allergen)|interpro:IPR013766(Thioredoxin domain)|interpro:IPR019479|interpro:IPR036249|mint:O08807|rcsb pdb:3VWU|rcsb pdb:3VWV|rcsb pdb:3W8J|rcsb pdb:3WGX|reactome:R-MMU-6798695	-	chain-seq-start:60|chain-seq-end:166	-	figure legend:ST1.2|comment:DTT-eluted fraction|dataset:Rare diseases - Interactions investigated in the context of Rare genetic disease|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2020/12/04	2020/12/21	rogid:mvYK6+YgIN/WuGLBCWqsqPLfDyQ10090	rogid:86EzEedrO6v5Z2dnSB2fSPaV2hc10090	rigid:sUlyHN3eQirg+yWIik/3UpGEVS4	false	mutation:34-34	-	-	-	psi-mi:"MI:0082"(peptide massfingerprinting)	psi-mi:"MI:0082"(peptide massfingerprinting)
uniprotkb:P97493-PRO_0000034151	uniprotkb:Q61171	intact:EBI-26567598	intact:EBI-444957|uniprotkb:O88376|uniprotkb:Q60796|uniprotkb:Q9CWJ4|uniprotkb:Q9DB49|ensembl:ENSMUSP00000005292|ensembl:ENSMUSP00000105355|ensembl:ENSMUSP00000105356|ensembl:ENSMUSP00000126451	psi-mi:p97493-pro_0000034151(display_long)|uniprotkb:Thioredoxin-2(gene name synonym)|uniprotkb:Txn2(gene name)|psi-mi:Txn2(display_short)	psi-mi:prdx2_mouse(display_long)|uniprotkb:Thioredoxin-dependent peroxiredoxin 2(gene name synonym)|uniprotkb:Thioredoxin peroxidase 1(gene name synonym)|uniprotkb:Thioredoxin-dependent peroxide reductase 1(gene name synonym)|uniprotkb:Thiol-specific antioxidant protein(gene name synonym)|uniprotkb:Prdx2(gene name)|psi-mi:Prdx2(display_short)|uniprotkb:Tdpx1(gene name synonym)|uniprotkb:Tpx(gene name synonym)	psi-mi:"MI:0096"(pull down)	Chasapis et al. (2019)	pubmed:31018154|imex:IM-28571	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26499997|imex:IM-28571-41	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	intact:EBI-8354432(chain-parent)	refseq:NP_035693.3|go:"GO:0042098"(T cell proliferation)|go:"GO:0042743"(hydrogen peroxide metabolic process)|go:"GO:0042744"(hydrogen peroxide catabolic process)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0043209"(myelin sheath)|go:"GO:0043410"(positive regulation of MAPK cascade)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0045321"(leukocyte activation)|go:"GO:0045454"(cell redox homeostasis)|go:"GO:0045581"(negative regulation of T cell differentiation)|go:"GO:0048538"(thymus development)|go:"GO:0048872"(homeostasis of number of cells)|go:"GO:2001237"(negative regulation of extrinsic apoptotic signaling pathway)|go:"GO:2001240"(negative regulation of extrinsic apoptotic signaling pathway in absence of ligand)|interpro:IPR000866(Alkyl hydroperoxide reductase/ Thiol specific antioxidant/ Mal allergen)|interpro:IPR013766(Thioredoxin domain)|interpro:IPR019479|interpro:IPR024706|interpro:IPR036249|mint:Q61171|reactome:R-MMU-3299685|reactome:R-MMU-5628897|go:"GO:0034599"(cellular response to oxidative stress)|refseq:NP_001304314.1|ensembl:ENSMUSG00000005161(gene)|ensembl:ENSMUST00000005292(transcript)|ensembl:ENSMUST00000109733(transcript)|ensembl:ENSMUST00000109734(transcript)|ensembl:ENSMUST00000164807(transcript)|go:"GO:0002357"(defense response to tumor cell)|go:"GO:0002536"(respiratory burst involved in inflammatory response)|go:"GO:0004601"(peroxidase activity)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0006979"(response to oxidative stress)|go:"GO:0008379"(thioredoxin peroxidase activity)|go:"GO:0008430"(selenium binding)|go:"GO:0010310"(regulation of hydrogen peroxide metabolic process)|go:"GO:0016209"(antioxidant activity)|go:"GO:0019430"(removal of superoxide radicals)|go:"GO:0030194"(positive regulation of blood coagulation)|go:"GO:0031665"(negative regulation of lipopolysaccharide-mediated signaling pathway)|go:"GO:0032088"(negative regulation of NF-kappaB transcription factor activity)|go:"GO:0032496"(response to lipopolysaccharide)	-	chain-seq-start:60|chain-seq-end:166	-	figure legend:ST1.2|comment:DTT-eluted fraction|dataset:Rare diseases - Interactions investigated in the context of Rare genetic disease|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2020/12/04	2020/12/21	rogid:mvYK6+YgIN/WuGLBCWqsqPLfDyQ10090	rogid:P1NxwIOnv1n4sNzQWtFjy2znSbA10090	rigid:sUlyHN3eQirg+yWIik/3UpGEVS4	false	mutation:34-34	-	-	-	psi-mi:"MI:0082"(peptide massfingerprinting)	psi-mi:"MI:0082"(peptide massfingerprinting)
uniprotkb:P97493-PRO_0000034151	uniprotkb:P35700	intact:EBI-26567598	intact:EBI-444948|uniprotkb:Q3UBV4|uniprotkb:Q9CWI2|ensembl:ENSMUSP00000102078|ensembl:ENSMUSP00000114159	psi-mi:p97493-pro_0000034151(display_long)|uniprotkb:Thioredoxin-2(gene name synonym)|uniprotkb:Txn2(gene name)|psi-mi:Txn2(display_short)	psi-mi:prdx1_mouse(display_long)|uniprotkb:Thioredoxin-dependent peroxiredoxin 1(gene name synonym)|uniprotkb:Thioredoxin-dependent peroxide reductase 2(gene name synonym)|uniprotkb:Osteoblast-specific factor 3(gene name synonym)|uniprotkb:Macrophage 23 kDa stress protein(gene name synonym)|uniprotkb:Thioredoxin peroxidase 2(gene name synonym)|uniprotkb:Prdx1(gene name)|psi-mi:Prdx1(display_short)|uniprotkb:Msp23(gene name synonym)|uniprotkb:Paga(gene name synonym)|uniprotkb:Tdpx2(gene name synonym)	psi-mi:"MI:0096"(pull down)	Chasapis et al. (2019)	pubmed:31018154|imex:IM-28571	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26499997|imex:IM-28571-41	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	intact:EBI-8354432(chain-parent)	refseq:NP_035164.1|ensembl:ENSMUST00000135573(transcript)|go:"GO:0000302"(response to reactive oxygen species)|go:"GO:0000791"(euchromatin)|go:"GO:0004601"(peroxidase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0005782"(peroxisomal matrix)|go:"GO:0005829"(cytosol)|go:"GO:0006979"(response to oxidative stress)|go:"GO:0008283"(cell population proliferation)|go:"GO:0008379"(thioredoxin peroxidase activity)|go:"GO:0019430"(removal of superoxide radicals)|go:"GO:0020037"(heme binding)|go:"GO:0030101"(natural killer cell activation)|go:"GO:0032872"(regulation of stress-activated MAPK cascade)|go:"GO:0034101"(erythrocyte homeostasis)|go:"GO:0042267"(natural killer cell mediated cytotoxicity)|go:"GO:0042744"(hydrogen peroxide catabolic process)|go:"GO:0042802"(identical protein binding)|go:"GO:0043209"(myelin sheath)|go:"GO:0045321"(leukocyte activation)|go:"GO:0045454"(cell redox homeostasis)|go:"GO:0051920"(peroxiredoxin activity)|go:"GO:1901222"(regulation of NIK/NF-kappaB signaling)|interpro:IPR000866(Alkyl hydroperoxide reductase/ Thiol specific antioxidant/ Mal allergen)|interpro:IPR013766(Thioredoxin domain)|interpro:IPR019479|interpro:IPR024706|interpro:IPR036249|mint:P35700|reactome:R-MMU-3299685|reactome:R-MMU-5628897|ensembl:ENSMUST00000106470(transcript)|ensembl:ENSMUSG00000028691(gene)	-	chain-seq-start:60|chain-seq-end:166	-	figure legend:ST1.2|comment:DTT-eluted fraction|dataset:Rare diseases - Interactions investigated in the context of Rare genetic disease|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2020/12/04	2020/12/21	rogid:mvYK6+YgIN/WuGLBCWqsqPLfDyQ10090	rogid:xOppWev1GtpILoJ1rY+tSPoymVU10090	rigid:sUlyHN3eQirg+yWIik/3UpGEVS4	false	mutation:34-34	-	-	-	psi-mi:"MI:0082"(peptide massfingerprinting)	psi-mi:"MI:0082"(peptide massfingerprinting)
uniprotkb:P97493-PRO_0000034151	uniprotkb:Q9JHL1	intact:EBI-26567598	intact:EBI-538451|uniprotkb:Q3TDR3|uniprotkb:Q6P074|uniprotkb:Q8BGL9|uniprotkb:Q8BW05|uniprotkb:Q9DCR6	psi-mi:p97493-pro_0000034151(display_long)|uniprotkb:Thioredoxin-2(gene name synonym)|uniprotkb:Txn2(gene name)|psi-mi:Txn2(display_short)	psi-mi:nhrf2_mouse(display_long)|uniprotkb:Tyrosine kinase activator protein 1(gene name synonym)|uniprotkb:SRY-interacting protein 1(gene name synonym)|uniprotkb:Solute carrier family 9 isoform A3 regulatory factor 2(gene name synonym)|uniprotkb:NHE3 kinase A regulatory protein E3KARP(gene name synonym)|uniprotkb:Sodium-hydrogen exchanger regulatory factor 2(gene name synonym)|uniprotkb:Octs2(gene name synonym)|uniprotkb:Slc9a3r2(gene name)|psi-mi:Slc9a3r2(display_short)|uniprotkb:Nherf2(gene name synonym)	psi-mi:"MI:0096"(pull down)	Chasapis et al. (2019)	pubmed:31018154|imex:IM-28571	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26499997|imex:IM-28571-41	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	intact:EBI-8354432(chain-parent)	refseq:NP_075542.2|refseq:NP_075938.2|interpro:IPR015098(EBP50, C-terminal)|interpro:IPR017300("Na(+)/H(+) exchange regulatory cofactor NHE-RF")|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR036034|interpro:IPR031197|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0007605"(sensory perception of sound)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0012505"(endomembrane system)|go:"GO:0014067"(negative regulation of phosphatidylinositol 3-kinase signaling)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0019902"(phosphatase binding)|go:"GO:0032420"(stereocilium)|go:"GO:0032421"(stereocilium bundle)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034767"(positive regulation of ion transmembrane transport)|go:"GO:0042802"(identical protein binding)|go:"GO:0043495"(protein-membrane adaptor activity)|go:"GO:0047485"(protein N-terminus binding)|go:"GO:0050750"(low-density lipoprotein particle receptor binding)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0008022"(protein C-terminus binding)|mint:Q9JHL1	-	chain-seq-start:60|chain-seq-end:166	-	figure legend:ST1.2|comment:DTT-eluted fraction|dataset:Rare diseases - Interactions investigated in the context of Rare genetic disease|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2020/12/04	2020/12/21	rogid:mvYK6+YgIN/WuGLBCWqsqPLfDyQ10090	rogid:479nbF0TYY11Q1dSVT26LwYoyiA10090	rigid:sUlyHN3eQirg+yWIik/3UpGEVS4	false	mutation:34-34	-	-	-	psi-mi:"MI:0082"(peptide massfingerprinting)	psi-mi:"MI:0082"(peptide massfingerprinting)
uniprotkb:P97493-PRO_0000034151	uniprotkb:Q61792	intact:EBI-26567598	intact:EBI-774513|uniprotkb:Q62416|ensembl:ENSMUSP00000042123	psi-mi:p97493-pro_0000034151(display_long)|uniprotkb:Thioredoxin-2(gene name synonym)|uniprotkb:Txn2(gene name)|psi-mi:Txn2(display_short)	psi-mi:lasp1_mouse(display_long)|uniprotkb:Metastatic lymph node gene 50 protein(gene name synonym)|uniprotkb:Lasp1(gene name)|psi-mi:Lasp1(display_short)|uniprotkb:Mln50(gene name synonym)	psi-mi:"MI:0096"(pull down)	Chasapis et al. (2019)	pubmed:31018154|imex:IM-28571	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26499997|imex:IM-28571-41	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	intact:EBI-8354432(chain-parent)	refseq:NP_034818.1|refseq:XP_006532404.1|ensembl:ENSMUSG00000038366(gene)|ensembl:ENSMUST00000043843(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0005925"(focal adhesion)|go:"GO:0006811"(ion transport)|go:"GO:0015075"(ion transmembrane transporter activity)|go:"GO:0030864"(cortical actin cytoskeleton)|go:"GO:0046872"(metal ion binding)|go:"GO:0051015"(actin filament binding)|interpro:IPR000900(Nebulin 35 residue motif)|interpro:IPR001452(Src homology-3)|interpro:IPR001781(Zinc finger, LIM-type)|interpro:IPR035630|interpro:IPR036028|mint:Q61792	-	chain-seq-start:60|chain-seq-end:166	-	figure legend:ST1.2|comment:DTT-eluted fraction|dataset:Rare diseases - Interactions investigated in the context of Rare genetic disease|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2020/12/04	2020/12/21	rogid:mvYK6+YgIN/WuGLBCWqsqPLfDyQ10090	rogid:bjQIqialH4yN2opuXwGU1XG2q8g10090	rigid:sUlyHN3eQirg+yWIik/3UpGEVS4	false	mutation:34-34	-	-	-	psi-mi:"MI:0082"(peptide massfingerprinting)	psi-mi:"MI:0082"(peptide massfingerprinting)
uniprotkb:P97493-PRO_0000034151	uniprotkb:Q8R081	intact:EBI-26567598	intact:EBI-647483|uniprotkb:O54789|uniprotkb:Q8K0S7|uniprotkb:Q499X2|ensembl:ENSMUSP00000049407|ensembl:ENSMUSP00000133728	psi-mi:p97493-pro_0000034151(display_long)|uniprotkb:Thioredoxin-2(gene name synonym)|uniprotkb:Txn2(gene name)|psi-mi:Txn2(display_short)	psi-mi:hnrpl_mouse(display_long)|uniprotkb:Hnrpl(gene name synonym)|uniprotkb:Hnrnpl(gene name)|psi-mi:Hnrnpl(display_short)	psi-mi:"MI:0096"(pull down)	Chasapis et al. (2019)	pubmed:31018154|imex:IM-28571	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26499997|imex:IM-28571-41	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	intact:EBI-8354432(chain-parent)	refseq:NP_796275.3|refseq:XP_006539621.1|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR006536(HnRNP-L/PTB/hephaestus splicing factor)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR021790|interpro:IPR034816|interpro:IPR034817|interpro:IPR035005|interpro:IPR035008|interpro:IPR035979|mint:Q8R081|rcsb pdb:3S01|rcsb pdb:3TYT|reactome:R-MMU-72163|reactome:R-MMU-72203|go:"GO:1990715"(mRNA CDS binding)|ensembl:ENSMUSG00000015165(gene)|ensembl:ENSMUST00000038572(transcript)|ensembl:ENSMUST00000174548(transcript)|go:"GO:0000381"(regulation of alternative mRNA splicing, via spliceosome)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0003730"(mRNA 3'-UTR binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006397"(mRNA processing)|go:"GO:0034198"(cellular response to amino acid starvation)|go:"GO:0035770"(ribonucleoprotein granule)|go:"GO:0043484"(regulation of RNA splicing)|go:"GO:0045120"(pronucleus)|go:"GO:0045727"(positive regulation of translation)|go:"GO:0048025"(negative regulation of mRNA splicing, via spliceosome)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0097157"(pre-mRNA intronic binding)|go:"GO:1902416"(positive regulation of mRNA binding)	-	chain-seq-start:60|chain-seq-end:166	-	figure legend:ST1.2|comment:DTT-eluted fraction|dataset:Rare diseases - Interactions investigated in the context of Rare genetic disease|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2020/12/04	2020/12/21	rogid:mvYK6+YgIN/WuGLBCWqsqPLfDyQ10090	rogid:BApt4fekoyJ285Ve13kxstcLbV010090	rigid:sUlyHN3eQirg+yWIik/3UpGEVS4	false	mutation:34-34	-	-	-	psi-mi:"MI:0082"(peptide massfingerprinting)	psi-mi:"MI:0082"(peptide massfingerprinting)
uniprotkb:P97493-PRO_0000034151	uniprotkb:O35737	intact:EBI-26567598	intact:EBI-299747|ensembl:ENSMUSP00000070503|ensembl:ENSMUSP00000104770	psi-mi:p97493-pro_0000034151(display_long)|uniprotkb:Thioredoxin-2(gene name synonym)|uniprotkb:Txn2(gene name)|psi-mi:Txn2(display_short)	psi-mi:hnrh1_mouse(display_long)|uniprotkb:Hnrnph1(gene name)|psi-mi:Hnrnph1(display_short)|uniprotkb:Hnrph(gene name synonym)|uniprotkb:Hnrph1(gene name synonym)	psi-mi:"MI:0096"(pull down)	Chasapis et al. (2019)	pubmed:31018154|imex:IM-28571	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26499997|imex:IM-28571-41	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	intact:EBI-8354432(chain-parent)	ensembl:ENSMUSG00000007850(gene)|ensembl:ENSMUST00000069304(transcript)|ensembl:ENSMUST00000109142(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006397"(mRNA processing)|go:"GO:0008380"(RNA splicing)|go:"GO:0042802"(identical protein binding)|go:"GO:0043484"(regulation of RNA splicing)|go:"GO:0071013"(catalytic step 2 spliceosome)|go:"GO:0098761"(cellular response to interleukin-7)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR012996(Zinc finger, CHHC-type)|interpro:IPR035979|mint:O35737|reactome:R-MMU-6803529|reactome:R-MMU-72163|reactome:R-MMU-72203|refseq:NP_067485.1|refseq:XP_017170179.1|refseq:XP_017170180.1	-	chain-seq-start:60|chain-seq-end:166	-	figure legend:ST1.2|comment:DTT-eluted fraction|dataset:Rare diseases - Interactions investigated in the context of Rare genetic disease|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2020/12/04	2020/12/21	rogid:mvYK6+YgIN/WuGLBCWqsqPLfDyQ10090	rogid:nBSCiXDDfkwqslFAXPXlDzC+5e410090	rigid:sUlyHN3eQirg+yWIik/3UpGEVS4	false	mutation:34-34	-	-	-	psi-mi:"MI:0082"(peptide massfingerprinting)	psi-mi:"MI:0082"(peptide massfingerprinting)
uniprotkb:P97493-PRO_0000034151	uniprotkb:Q9Z2X1	intact:EBI-26567598	intact:EBI-4283704|uniprotkb:Q5FWK2|uniprotkb:Q8BVU8|uniprotkb:Q8K2U9|uniprotkb:Q8R0E7|ensembl:ENSMUSP00000045048|ensembl:ENSMUSP00000126817|ensembl:ENSMUSP00000130023|ensembl:ENSMUSP00000136700|ensembl:ENSMUSP00000137632	psi-mi:p97493-pro_0000034151(display_long)|uniprotkb:Thioredoxin-2(gene name synonym)|uniprotkb:Txn2(gene name)|psi-mi:Txn2(display_short)	psi-mi:hnrpf_mouse(display_long)|uniprotkb:Hnrnpf(gene name)|psi-mi:Hnrnpf(display_short)|uniprotkb:Hnrpf(gene name synonym)	psi-mi:"MI:0096"(pull down)	Chasapis et al. (2019)	pubmed:31018154|imex:IM-28571	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26499997|imex:IM-28571-41	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	intact:EBI-8354432(chain-parent)	refseq:NP_001159899.1|refseq:NP_001159900.1|refseq:NP_001159901.1|refseq:NP_001159902.1|refseq:NP_001159903.1|refseq:NP_001159904.1|refseq:NP_598595.1|refseq:XP_006506892.1|ensembl:ENSMUSG00000042079(gene)|ensembl:ENSMUST00000035493(transcript)|ensembl:ENSMUST00000163168(transcript)|ensembl:ENSMUST00000167182(transcript)|ensembl:ENSMUST00000180020(transcript)|ensembl:ENSMUST00000180341(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0003727"(single-stranded RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006397"(mRNA processing)|go:"GO:0008380"(RNA splicing)|go:"GO:0017025"(TBP-class protein binding)|go:"GO:0043484"(regulation of RNA splicing)|go:"GO:0071013"(catalytic step 2 spliceosome)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR012996(Zinc finger, CHHC-type)|interpro:IPR035979|rcsb pdb:2DB1|reactome:R-MMU-6803529|reactome:R-MMU-72163|reactome:R-MMU-72203|mint:Q9Z2X1	-	chain-seq-start:60|chain-seq-end:166	-	figure legend:ST1.2|comment:DTT-eluted fraction|dataset:Rare diseases - Interactions investigated in the context of Rare genetic disease|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2020/12/04	2020/12/21	rogid:mvYK6+YgIN/WuGLBCWqsqPLfDyQ10090	rogid:Ntkz1kjm7RteL6dBzMmC0sipvCk10090	rigid:sUlyHN3eQirg+yWIik/3UpGEVS4	false	mutation:34-34	-	-	-	psi-mi:"MI:0082"(peptide massfingerprinting)	psi-mi:"MI:0082"(peptide massfingerprinting)
uniprotkb:P97493-PRO_0000034151	uniprotkb:Q60668	intact:EBI-26567598	intact:EBI-299932|ensembl:ENSMUSP00000132735|uniprotkb:Q91X94|uniprotkb:Q60667|uniprotkb:Q80ZJ0	psi-mi:p97493-pro_0000034151(display_long)|uniprotkb:Thioredoxin-2(gene name synonym)|uniprotkb:Txn2(gene name)|psi-mi:Txn2(display_short)	psi-mi:hnrpd_mouse(display_long)|uniprotkb:Hnrnpd(gene name)|psi-mi:Hnrnpd(display_short)|uniprotkb:Auf1(gene name synonym)|uniprotkb:Hnrpd(gene name synonym)|uniprotkb:AU-rich element RNA-binding protein 1(gene name synonym)	psi-mi:"MI:0096"(pull down)	Chasapis et al. (2019)	pubmed:31018154|imex:IM-28571	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26499997|imex:IM-28571-41	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	intact:EBI-8354432(chain-parent)	ensembl:ENSMUSG00000000568(gene)|ensembl:ENSMUST00000172361(transcript)|go:"GO:0001889"(liver development)|go:"GO:0003680"(minor groove of adenine-thymine-rich DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0021549"(cerebellum development)|go:"GO:0032204"(regulation of telomere maintenance)|go:"GO:0035925"(mRNA 3'-UTR AU-rich region binding)|go:"GO:0042162"(telomeric DNA binding)|go:"GO:0042789"(mRNA transcription by RNA polymerase II)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0043488"(regulation of mRNA stability)|go:"GO:0045202"(synapse)|go:"GO:0045727"(positive regulation of translation)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048255"(mRNA stabilization)|go:"GO:0051592"(response to calcium ion)|go:"GO:0051602"(response to electrical stimulus)|go:"GO:0061158"(3'-UTR-mediated mRNA destabilization)|go:"GO:0071230"(cellular response to amino acid stimulus)|go:"GO:0071392"(cellular response to estradiol stimulus)|go:"GO:0071732"(cellular response to nitric oxide)|go:"GO:0097167"(circadian regulation of translation)|go:"GO:1901355"(response to rapamycin)|go:"GO:1904355"(positive regulation of telomere capping)|go:"GO:1904383"(response to sodium phosphate)|go:"GO:1904586"(cellular response to putrescine)|go:"GO:1905663"(positive regulation of telomerase RNA reverse transcriptase activity)|go:"GO:1990828"(hepatocyte dedifferentiation)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR012956(CBF, N-terminal)|interpro:IPR035979|mint:Q60668|reactome:R-MMU-450408|reactome:R-MMU-72163|reactome:R-MMU-72203|go:"GO:0042752"(regulation of circadian rhythm)|refseq:NP_001070733.1|refseq:NP_001070734.1|refseq:NP_001070735.1|refseq:NP_031542.2|refseq:XP_006534798.1|dip:DIP-31411N	-	chain-seq-start:60|chain-seq-end:166	-	figure legend:ST1.2|comment:DTT-eluted fraction|dataset:Rare diseases - Interactions investigated in the context of Rare genetic disease|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2020/12/04	2020/12/21	rogid:mvYK6+YgIN/WuGLBCWqsqPLfDyQ10090	rogid:lGvmHnn59pHQTtZq6H6ijlvXvt010090	rigid:sUlyHN3eQirg+yWIik/3UpGEVS4	false	mutation:34-34	-	-	-	psi-mi:"MI:0082"(peptide massfingerprinting)	psi-mi:"MI:0082"(peptide massfingerprinting)
uniprotkb:P97493-PRO_0000034151	uniprotkb:P02088	intact:EBI-26567598	intact:EBI-494201|uniprotkb:Q54AI0|uniprotkb:Q91V86|uniprotkb:Q9CRZ2|uniprotkb:Q9CXH5|uniprotkb:Q9CY12|uniprotkb:Q9CY54|uniprotkb:Q9R0S6	psi-mi:p97493-pro_0000034151(display_long)|uniprotkb:Thioredoxin-2(gene name synonym)|uniprotkb:Txn2(gene name)|psi-mi:Txn2(display_short)	psi-mi:hbb1_mouse(display_long)|uniprotkb:Hemoglobin beta-1 chain(gene name synonym)|uniprotkb:Beta-1-globin(gene name synonym)|uniprotkb:Hemoglobin beta-major chain(gene name synonym)|uniprotkb:Hbb-b1(gene name)|psi-mi:Hbb-b1(display_short)	psi-mi:"MI:0096"(pull down)	Chasapis et al. (2019)	pubmed:31018154|imex:IM-28571	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26499997|imex:IM-28571-41	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	intact:EBI-8354432(chain-parent)	refseq:NP_001188320.1|refseq:NP_032246.2|interpro:IPR009050(Globin-like)|interpro:IPR000971(Globin, subset)|interpro:IPR002337(Haemoglobin, beta)|interpro:IPR012292(Globin)|refseq:NP_001265090.1|go:"GO:0005344"(oxygen carrier activity)|go:"GO:0005833"(hemoglobin complex)|go:"GO:0010999"(regulation of eIF2 alpha phosphorylation by heme)|go:"GO:0015671"(oxygen transport)|go:"GO:0019825"(oxygen binding)|go:"GO:0020037"(heme binding)|go:"GO:0030097"(hemopoiesis)|go:"GO:0031721"(hemoglobin alpha binding)|go:"GO:0031838"(haptoglobin-hemoglobin complex)|go:"GO:0042744"(hydrogen peroxide catabolic process)|go:"GO:0043177"(organic acid binding)|go:"GO:0043209"(myelin sheath)|go:"GO:0046872"(metal ion binding)|go:"GO:0048821"(erythrocyte development)|go:"GO:0098869"(cellular oxidant detoxification)|rcsb pdb:1JEB|rcsb pdb:3HRW|mint:P02088	-	chain-seq-start:60|chain-seq-end:166	-	figure legend:ST1.2|comment:DTT-eluted fraction|dataset:Rare diseases - Interactions investigated in the context of Rare genetic disease|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2020/12/04	2020/12/21	rogid:mvYK6+YgIN/WuGLBCWqsqPLfDyQ10090	rogid:/W1Bo3qzhsm3Fzb/joImMwzE/Dg10090	rigid:sUlyHN3eQirg+yWIik/3UpGEVS4	false	mutation:34-34	-	-	-	psi-mi:"MI:0082"(peptide massfingerprinting)	psi-mi:"MI:0082"(peptide massfingerprinting)
uniprotkb:P97493-PRO_0000034151	uniprotkb:P16045	intact:EBI-26567598	intact:EBI-1634185|uniprotkb:P05163|uniprotkb:P11946|uniprotkb:P17601|uniprotkb:Q4FZH4|uniprotkb:Q99M27|uniprotkb:Q9D0X0|ensembl:ENSMUSP00000086795	psi-mi:p97493-pro_0000034151(display_long)|uniprotkb:Thioredoxin-2(gene name synonym)|uniprotkb:Txn2(gene name)|psi-mi:Txn2(display_short)	psi-mi:leg1_mouse(display_long)|uniprotkb:Lgals1(gene name)|psi-mi:Lgals1(display_short)|uniprotkb:Gbp(gene name synonym)|uniprotkb:Lectin galactoside-binding soluble 1(gene name synonym)|uniprotkb:Beta-galactoside-binding lectin L-14-I(gene name synonym)|uniprotkb:S-Lac lectin 1(gene name synonym)|uniprotkb:Galaptin(gene name synonym)|uniprotkb:14 kDa lectin(gene name synonym)|uniprotkb:Lactose-binding lectin 1(gene name synonym)	psi-mi:"MI:0096"(pull down)	Chasapis et al. (2019)	pubmed:31018154|imex:IM-28571	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26499997|imex:IM-28571-41	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	intact:EBI-8354432(chain-parent)	refseq:NP_032521.1|ensembl:ENSMUSG00000068220(gene)|ensembl:ENSMUST00000089377(transcript)|go:"GO:0002317"(plasma cell differentiation)|go:"GO:0005534"(galactose binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006915"(apoptotic process)|go:"GO:0007157"(heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules)|go:"GO:0009986"(cell surface)|go:"GO:0010812"(negative regulation of cell-substrate adhesion)|go:"GO:0010977"(negative regulation of neuron projection development)|go:"GO:0030246"(carbohydrate binding)|go:"GO:0030395"(lactose binding)|go:"GO:0031295"(T cell costimulation)|go:"GO:0034120"(positive regulation of erythrocyte aggregation)|go:"GO:0035900"(response to isolation stress)|go:"GO:0042493"|go:"GO:0042802"(identical protein binding)|go:"GO:0043236"(laminin binding)|go:"GO:0045445"(myoblast differentiation)|go:"GO:0046598"(positive regulation of viral entry into host cell)|go:"GO:0048678"(response to axon injury)|go:"GO:0062023"(collagen-containing extracellular matrix)|go:"GO:0071333"(cellular response to glucose stimulus)|go:"GO:0071407"(cellular response to organic cyclic compound)|interpro:IPR001079(Galectin, galactose-binding lectin)|interpro:IPR013320(Concanavalin A-like lectin/glucanase, subgroup)|interpro:IPR044156|mint:P16045|rcsb pdb:4LBQ|reactome:R-MMU-381426|reactome:R-MMU-8957275	-	chain-seq-start:60|chain-seq-end:166	-	figure legend:ST1.2|comment:DTT-eluted fraction|dataset:Rare diseases - Interactions investigated in the context of Rare genetic disease|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2020/12/04	2020/12/21	rogid:mvYK6+YgIN/WuGLBCWqsqPLfDyQ10090	rogid:VMxhs6wVhql3NEex38RQeIwirZs10090	rigid:sUlyHN3eQirg+yWIik/3UpGEVS4	false	mutation:34-34	-	-	-	psi-mi:"MI:0082"(peptide massfingerprinting)	psi-mi:"MI:0082"(peptide massfingerprinting)
uniprotkb:P97493-PRO_0000034151	uniprotkb:O35226	intact:EBI-26567598	intact:EBI-992034|uniprotkb:Q91V59|uniprotkb:Q9JJM0|uniprotkb:Q9JJM1|uniprotkb:Q9JJM2|uniprotkb:Q9JJM3|ensembl:ENSMUSP00000102857	psi-mi:p97493-pro_0000034151(display_long)|uniprotkb:Thioredoxin-2(gene name synonym)|uniprotkb:Txn2(gene name)|psi-mi:Txn2(display_short)	psi-mi:psmd4_mouse(display_long)|uniprotkb:26S proteasome regulatory subunit S5A(gene name synonym)|uniprotkb:26S proteasome regulatory subunit RPN10(gene name synonym)|uniprotkb:Multiubiquitin chain-binding protein(gene name synonym)|uniprotkb:Psmd4(gene name)|psi-mi:Psmd4(display_short)|uniprotkb:Mcb1(gene name synonym)	psi-mi:"MI:0096"(pull down)	Chasapis et al. (2019)	pubmed:31018154|imex:IM-28571	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26499997|imex:IM-28571-41	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	intact:EBI-8354432(chain-parent)	refseq:NP_032977.1|ensembl:ENSMUSG00000005625(gene)|ensembl:ENSMUST00000107237(transcript)|go:"GO:0000502"(proteasome complex)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0008540"(proteasome regulatory particle, base subcomplex)|go:"GO:0022624"(proteasome accessory complex)|go:"GO:0031593"(polyubiquitin modification-dependent protein binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0043248"(proteasome assembly)|interpro:IPR003903(Ubiquitin interacting motif)|interpro:IPR002035(von Willebrand factor, type A)|interpro:IPR036465|mint:O35226|reactome:R-MMU-1169091|reactome:R-MMU-1234176|reactome:R-MMU-1236978|reactome:R-MMU-174084|reactome:R-MMU-174154|reactome:R-MMU-174178|reactome:R-MMU-174184|reactome:R-MMU-187577|reactome:R-MMU-195253|reactome:R-MMU-202424|reactome:R-MMU-2467813|reactome:R-MMU-2871837|reactome:R-MMU-349425|reactome:R-MMU-350562|reactome:R-MMU-382556|reactome:R-MMU-450408|reactome:R-MMU-4641257|reactome:R-MMU-4641258|reactome:R-MMU-5358346|reactome:R-MMU-5607761|reactome:R-MMU-5607764|reactome:R-MMU-5610780|reactome:R-MMU-5610785|reactome:R-MMU-5632684|reactome:R-MMU-5658442|reactome:R-MMU-5668541|reactome:R-MMU-5676590|reactome:R-MMU-5687128|reactome:R-MMU-5689603|reactome:R-MMU-5689880|reactome:R-MMU-68827|reactome:R-MMU-68949|reactome:R-MMU-69017|reactome:R-MMU-69481|reactome:R-MMU-69601|reactome:R-MMU-75815|reactome:R-MMU-8852276|reactome:R-MMU-8854050|reactome:R-MMU-8932339|reactome:R-MMU-4608870|reactome:R-MMU-8939236|reactome:R-MMU-8939902|reactome:R-MMU-8941858|reactome:R-MMU-8951664|reactome:R-MMU-9020702|reactome:R-MMU-983168|reactome:R-MMU-8948751|refseq:NP_001268946.1	-	chain-seq-start:60|chain-seq-end:166	-	figure legend:ST1.2|comment:DTT-eluted fraction|dataset:Rare diseases - Interactions investigated in the context of Rare genetic disease|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2020/12/04	2020/12/21	rogid:mvYK6+YgIN/WuGLBCWqsqPLfDyQ10090	rogid:foAsSSZ5pvYhKvPA4XUyZCVjo3010090	rigid:sUlyHN3eQirg+yWIik/3UpGEVS4	false	mutation:34-34	-	-	-	psi-mi:"MI:0082"(peptide massfingerprinting)	psi-mi:"MI:0082"(peptide massfingerprinting)
uniprotkb:P97493-PRO_0000034151	uniprotkb:Q8BTM8	intact:EBI-26567598	intact:EBI-641991|uniprotkb:B7FAV0|uniprotkb:O54934|uniprotkb:Q7TQI1|uniprotkb:Q8BLK1|uniprotkb:Q8BTN7|uniprotkb:Q8VHX5|uniprotkb:Q8VHX8|uniprotkb:Q99KQ2|ensembl:ENSMUSP00000033699	psi-mi:p97493-pro_0000034151(display_long)|uniprotkb:Thioredoxin-2(gene name synonym)|uniprotkb:Txn2(gene name)|psi-mi:Txn2(display_short)	psi-mi:flna_mouse(display_long)|uniprotkb:Alpha-filamin(gene name synonym)|uniprotkb:Filamin-1(gene name synonym)|uniprotkb:Endothelial actin-binding protein(gene name synonym)|uniprotkb:Actin-binding protein 280(gene name synonym)|uniprotkb:Non-muscle filamin(gene name synonym)|uniprotkb:Flna(gene name)|psi-mi:Flna(display_short)|uniprotkb:Fln(gene name synonym)|uniprotkb:Fln1(gene name synonym)	psi-mi:"MI:0096"(pull down)	Chasapis et al. (2019)	pubmed:31018154|imex:IM-28571	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26499997|imex:IM-28571-41	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	intact:EBI-8354432(chain-parent)	refseq:XP_006527974.1|ensembl:ENSMUST00000033699(transcript)|go:"GO:0001525"(angiogenesis)|go:"GO:0001664"(G protein-coupled receptor binding)|go:"GO:0001837"(epithelial to mesenchymal transition)|go:"GO:0001974"(blood vessel remodeling)|go:"GO:0003007"(heart morphogenesis)|go:"GO:0003779"(actin binding)|go:"GO:0005080"(protein kinase C binding)|go:"GO:0005634"(nucleus)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0005829"(cytosol)|go:"GO:0005884"(actin filament)|go:"GO:0005886"(plasma membrane)|go:"GO:0005903"(brush border)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005938"(cell cortex)|go:"GO:0007195"(adenylate cyclase-inhibiting dopamine receptor signaling pathway)|go:"GO:0008134"(transcription factor binding)|go:"GO:0010977"(negative regulation of neuron projection development)|go:"GO:0015459"(potassium channel regulator activity)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0016479"(negative regulation of transcription by RNA polymerase I)|go:"GO:0019900"(kinase binding)|go:"GO:0021943"(formation of radial glial scaffolds)|go:"GO:0021987"(cerebral cortex development)|ensembl:ENSMUSG00000031328(gene)|go:"GO:0043433"(negative regulation of DNA-binding transcription factor activity)|go:"GO:0044295"(axonal growth cone)|go:"GO:0044319"(wound healing, spreading of cells)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045022"(early endosome to late endosome transport)|go:"GO:0045184"(establishment of protein localization)|go:"GO:0045216"(cell-cell junction organization)|go:"GO:0046332"(SMAD binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0048680"(positive regulation of axon regeneration)|go:"GO:0050808"(synapse organization)|go:"GO:0050821"(protein stabilization)|go:"GO:0051015"(actin filament binding)|go:"GO:0051020"(GTPase binding)|go:"GO:0051220"(cytoplasmic sequestering of protein)|go:"GO:0051764"(actin crosslink formation)|go:"GO:0060271"(cilium assembly)|go:"GO:0071526"(semaphorin-plexin signaling pathway)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0090042"(tubulin deacetylation)|go:"GO:0090307"(mitotic spindle assembly)|go:"GO:0030018"(Z disc)|go:"GO:0030036"(actin cytoskeleton organization)|go:"GO:0030334"(regulation of cell migration)|go:"GO:0030426"(growth cone)|go:"GO:0030863"(cortical cytoskeleton)|go:"GO:0031267"(small GTPase binding)|go:"GO:0031523"(Myb complex)|go:"GO:0031532"(actin cytoskeleton reorganization)|go:"GO:0031852"(mu-type opioid receptor binding)|go:"GO:0032231"(regulation of actin filament bundle assembly)|go:"GO:0032233"(positive regulation of actin filament bundle assembly)|go:"GO:0032432"(actin filament bundle)|go:"GO:0034394"(protein localization to cell surface)|go:"GO:0034988"(Fc-gamma receptor I complex binding)|go:"GO:0042177"(negative regulation of protein catabolic process)|go:"GO:0042307"(positive regulation of protein import into nucleus)|go:"GO:0042789"(mRNA transcription by RNA polymerase II)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043113"(receptor clustering)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043198"(dendritic shaft)|go:"GO:0043204"(perikaryon)|go:"GO:0097440"(apical dendrite)|go:"GO:0098794"(postsynapse)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:1900026"(positive regulation of substrate adhesion-dependent cell spreading)|go:"GO:1901381"(positive regulation of potassium ion transmembrane transport)|go:"GO:1902396"(protein localization to bicellular tight junction)|go:"GO:1905000"(regulation of membrane repolarization during atrial cardiac muscle cell action potential)|go:"GO:1905031"(regulation of membrane repolarization during cardiac muscle cell action potential)|go:"GO:2000179"(positive regulation of neural precursor cell proliferation)|go:"GO:2001046"(positive regulation of integrin-mediated signaling pathway)|go:"GO:2001224"(positive regulation of neuron migration)|interpro:IPR001298(Filamin/ABP280 repeat)|interpro:IPR001589(Actinin-type, actin-binding, conserved site)|interpro:IPR001715(Calponin-like actin-binding)|go:"GO:0097368"(establishment of Sertoli cell barrier)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR014756(Immunoglobulin E-set)|interpro:IPR017868|interpro:IPR036872|interpro:IPR044801|mint:Q8BTM8|reactome:R-MMU-114608|reactome:R-MMU-430116|reactome:R-MMU-446353|reactome:R-MMU-5627123	-	chain-seq-start:60|chain-seq-end:166	-	figure legend:ST1.2|comment:DTT-eluted fraction|dataset:Rare diseases - Interactions investigated in the context of Rare genetic disease|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2020/12/04	2020/12/21	rogid:mvYK6+YgIN/WuGLBCWqsqPLfDyQ10090	rogid:hp3whHs7nFMTtChpQ/KywkPalq810090	rigid:sUlyHN3eQirg+yWIik/3UpGEVS4	false	mutation:34-34	-	-	-	psi-mi:"MI:0082"(peptide massfingerprinting)	psi-mi:"MI:0082"(peptide massfingerprinting)
uniprotkb:P97493-PRO_0000034151	uniprotkb:O08553	intact:EBI-26567598	intact:EBI-446064|uniprotkb:Q6P5D0|ensembl:ENSMUSP00000022629	psi-mi:p97493-pro_0000034151(display_long)|uniprotkb:Thioredoxin-2(gene name synonym)|uniprotkb:Txn2(gene name)|psi-mi:Txn2(display_short)	psi-mi:dpyl2_mouse(display_long)|uniprotkb:Unc-33-like phosphoprotein 2(gene name synonym)|uniprotkb:Dpysl2(gene name)|psi-mi:Dpysl2(display_short)|uniprotkb:Crmp2(gene name synonym)|uniprotkb:Ulip2(gene name synonym)	psi-mi:"MI:0096"(pull down)	Chasapis et al. (2019)	pubmed:31018154|imex:IM-28571	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26499997|imex:IM-28571-41	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	intact:EBI-8354432(chain-parent)	refseq:NP_034085.2|ensembl:ENSMUSG00000022048(gene)|ensembl:ENSMUST00000022629(transcript)|go:"GO:0001975"(response to amphetamine)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005886"(plasma membrane)|go:"GO:0006897"(endocytosis)|go:"GO:0007010"(cytoskeleton organization)|go:"GO:0007411"(axon guidance)|go:"GO:0008017"(microtubule binding)|go:"GO:0010975"(regulation of neuron projection development)|go:"GO:0014049"(positive regulation of glutamate secretion)|go:"GO:0016810"("hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds")|go:"GO:0019901"(protein kinase binding)|go:"GO:0021510"(spinal cord development)|go:"GO:0021772"(olfactory bulb development)|go:"GO:0030424"(axon)|go:"GO:0030425"(dendrite)|go:"GO:0030426"(growth cone)|go:"GO:0030516"(regulation of axon extension)|go:"GO:0032991"(protein-containing complex)|go:"GO:0042220"(response to cocaine)|go:"GO:0042493"|go:"GO:0042802"(identical protein binding)|go:"GO:0043005"(neuron projection)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043195"(terminal bouton)|go:"GO:0043209"(myelin sheath)|go:"GO:0045664"(regulation of neuron differentiation)|go:"GO:0048489"(synaptic vesicle transport)|go:"GO:0098793"(presynapse)|interpro:IPR006680(Amidohydrolase 1)|interpro:IPR011059(Metal-dependent hydrolase, composite)|interpro:IPR011778(D-hydantoinase)|interpro:IPR030615|interpro:IPR032466|mint:O08553|rcsb pdb:5UQC|reactome:R-MMU-399956|reactome:R-MMU-437239	-	chain-seq-start:60|chain-seq-end:166	-	figure legend:ST1.2|comment:DTT-eluted fraction|dataset:Rare diseases - Interactions investigated in the context of Rare genetic disease|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2020/12/04	2020/12/21	rogid:mvYK6+YgIN/WuGLBCWqsqPLfDyQ10090	rogid:97yc8TNEPMcGtGNRLvl+KV+DYr010090	rigid:sUlyHN3eQirg+yWIik/3UpGEVS4	false	mutation:34-34	-	-	-	psi-mi:"MI:0082"(peptide massfingerprinting)	psi-mi:"MI:0082"(peptide massfingerprinting)
uniprotkb:P97493-PRO_0000034151	uniprotkb:Q9R0P5	intact:EBI-26567598	intact:EBI-1184008|ensembl:ENSMUSP00000099461	psi-mi:p97493-pro_0000034151(display_long)|uniprotkb:Thioredoxin-2(gene name synonym)|uniprotkb:Txn2(gene name)|psi-mi:Txn2(display_short)	psi-mi:dest_mouse(display_long)|uniprotkb:Dstn(gene name)|psi-mi:Dstn(display_short)|uniprotkb:Dsn(gene name synonym)|uniprotkb:Sid23(gene name synonym)|uniprotkb:Actin-depolymerizing factor(gene name synonym)|uniprotkb:Sid 23(gene name synonym)	psi-mi:"MI:0096"(pull down)	Chasapis et al. (2019)	pubmed:31018154|imex:IM-28571	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26499997|imex:IM-28571-41	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	intact:EBI-8354432(chain-parent)	refseq:NP_062745.1|ensembl:ENSMUSG00000015932(gene)|ensembl:ENSMUST00000103172(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0030042"(actin filament depolymerization)|go:"GO:0030043"(actin filament fragmentation)|go:"GO:0030836"(positive regulation of actin filament depolymerization)|go:"GO:0030864"(cortical actin cytoskeleton)|go:"GO:0048870"(cell motility)|go:"GO:0051014"(actin filament severing)|go:"GO:0051015"(actin filament binding)|interpro:IPR002108(Actin-binding, cofilin/tropomyosin type)|interpro:IPR017904|interpro:IPR029006|interpro:IPR029924|mint:Q9R0P5	-	chain-seq-start:60|chain-seq-end:166	-	figure legend:ST1.2|comment:DTT-eluted fraction|dataset:Rare diseases - Interactions investigated in the context of Rare genetic disease|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2020/12/04	2020/12/21	rogid:mvYK6+YgIN/WuGLBCWqsqPLfDyQ10090	rogid:hqPae8VWEKvGPITqHtrSs78yI4M10090	rigid:sUlyHN3eQirg+yWIik/3UpGEVS4	false	mutation:34-34	-	-	-	psi-mi:"MI:0082"(peptide massfingerprinting)	psi-mi:"MI:0082"(peptide massfingerprinting)
uniprotkb:P97493-PRO_0000034151	uniprotkb:P18760	intact:EBI-26567598	intact:EBI-1183994|ensembl:ENSMUSP00000147514	psi-mi:p97493-pro_0000034151(display_long)|uniprotkb:Thioredoxin-2(gene name synonym)|uniprotkb:Txn2(gene name)|psi-mi:Txn2(display_short)	psi-mi:cof1_mouse(display_long)|uniprotkb:Cfl1(gene name)|psi-mi:Cfl1(display_short)|uniprotkb:Cofilin, non-muscle isoform(gene name synonym)	psi-mi:"MI:0096"(pull down)	Chasapis et al. (2019)	pubmed:31018154|imex:IM-28571	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26499997|imex:IM-28571-41	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	intact:EBI-8354432(chain-parent)	refseq:NP_031713.1|ensembl:ENSMUSG00000056201(gene)|ensembl:ENSMUST00000209469(transcript)|go:"GO:0000281"(mitotic cytokinesis)|go:"GO:0001755"(neural crest cell migration)|go:"GO:0001842"(neural fold formation)|go:"GO:0003779"(actin binding)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005925"(focal adhesion)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0007010"(cytoskeleton organization)|go:"GO:0007015"(actin filament organization)|go:"GO:0007162"(negative regulation of cell adhesion)|go:"GO:0010592"(positive regulation of lamellipodium assembly)|go:"GO:0010593"(negative regulation of lamellipodium assembly)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0016363"(nuclear matrix)|go:"GO:0019903"(protein phosphatase binding)|go:"GO:0022604"(regulation of cell morphogenesis)|go:"GO:0030010"(establishment of cell polarity)|go:"GO:0030027"(lamellipodium)|go:"GO:0030030"(cell projection organization)|go:"GO:0030042"(actin filament depolymerization)|go:"GO:0030043"(actin filament fragmentation)|go:"GO:0030175"(filopodium)|go:"GO:0030307"(positive regulation of cell growth)|go:"GO:0030426"(growth cone)|go:"GO:0030835"(negative regulation of actin filament depolymerization)|go:"GO:0030836"(positive regulation of actin filament depolymerization)|go:"GO:0030864"(cortical actin cytoskeleton)|go:"GO:0031252"(cell leading edge)|go:"GO:0031258"(lamellipodium membrane)|go:"GO:0031915"(positive regulation of synaptic plasticity)|go:"GO:0031966"(mitochondrial membrane)|go:"GO:0032232"(negative regulation of actin filament bundle assembly)|go:"GO:0032587"(ruffle membrane)|go:"GO:0040019"(positive regulation of embryonic development)|go:"GO:0043005"(neuron projection)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043197"(dendritic spine)|go:"GO:0043200"(response to amino acid)|go:"GO:0044794"(positive regulation by host of viral process)|go:"GO:0045792"(negative regulation of cell size)|go:"GO:0045862"(positive regulation of proteolysis)|go:"GO:0048870"(cell motility)|go:"GO:0051014"(actin filament severing)|go:"GO:0051015"(actin filament binding)|go:"GO:0051293"(establishment of spindle localization)|go:"GO:0051511"(negative regulation of unidimensional cell growth)|go:"GO:0051894"(positive regulation of focal adhesion assembly)|go:"GO:0060999"(positive regulation of dendritic spine development)|go:"GO:0061001"(regulation of dendritic spine morphogenesis)|go:"GO:0070301"(cellular response to hydrogen peroxide)|go:"GO:0071347"(cellular response to interleukin-1)|go:"GO:0071354"(cellular response to interleukin-6)|go:"GO:0071356"(cellular response to tumor necrosis factor)|go:"GO:0071364"(cellular response to epidermal growth factor stimulus)|go:"GO:0090732"(cofilin-actin rod)|go:"GO:0097060"(synaptic membrane)|go:"GO:0098885"(modification of postsynaptic actin cytoskeleton)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:1902936"(phosphatidylinositol bisphosphate binding)|go:"GO:1902951"(negative regulation of dendritic spine maintenance)|go:"GO:1904783"(positive regulation of NMDA glutamate receptor activity)|go:"GO:1905873"(positive regulation of protein localization to cell leading edge)|go:"GO:1905875"(negative regulation of postsynaptic density organization)|go:"GO:1990314"(cellular response to insulin-like growth factor stimulus)|go:"GO:2000146"(negative regulation of cell motility)|go:"GO:2000147"(positive regulation of cell motility)|go:"GO:2000784"(positive regulation of establishment of cell polarity regulating cell shape)|go:"GO:2000814"(positive regulation of barbed-end actin filament capping)|interpro:IPR002108(Actin-binding, cofilin/tropomyosin type)|interpro:IPR017904|interpro:IPR027234|interpro:IPR029006|mint:P18760|dip:DIP-38073N	-	chain-seq-start:60|chain-seq-end:166	-	figure legend:ST1.2|comment:DTT-eluted fraction|dataset:Rare diseases - Interactions investigated in the context of Rare genetic disease|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2020/12/04	2020/12/21	rogid:mvYK6+YgIN/WuGLBCWqsqPLfDyQ10090	rogid:nw/9u2+2nq9Ef43SapV43MeOtjE10090	rigid:sUlyHN3eQirg+yWIik/3UpGEVS4	false	mutation:34-34	-	-	-	psi-mi:"MI:0082"(peptide massfingerprinting)	psi-mi:"MI:0082"(peptide massfingerprinting)
uniprotkb:P97493-PRO_0000034151	uniprotkb:P53996	intact:EBI-26567598	intact:EBI-2552945|ensembl:ENSMUSP00000032138|uniprotkb:Q80Y06|uniprotkb:Q8BP23	psi-mi:p97493-pro_0000034151(display_long)|uniprotkb:Thioredoxin-2(gene name synonym)|uniprotkb:Txn2(gene name)|psi-mi:Txn2(display_short)	psi-mi:cnbp_mouse(display_long)|uniprotkb:Cnbp(gene name)|psi-mi:Cnbp(display_short)|uniprotkb:Cnbp1(gene name synonym)|uniprotkb:Znf9(gene name synonym)|uniprotkb:Zinc finger protein 9(gene name synonym)|uniprotkb:Cellular nucleic acid-binding protein(gene name synonym)	psi-mi:"MI:0096"(pull down)	Chasapis et al. (2019)	pubmed:31018154|imex:IM-28571	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26499997|imex:IM-28571-41	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	intact:EBI-8354432(chain-parent)	refseq:NP_001103215.1|refseq:NP_038521.1|ensembl:ENSMUSG00000030057(gene)|ensembl:ENSMUST00000032138(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0003727"(single-stranded RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005829"(cytosol)|go:"GO:0008270"(zinc ion binding)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0045182"(translation regulator activity)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0051880"(G-quadruplex DNA binding)|go:"GO:0071919"(G-quadruplex DNA formation)|go:"GO:2000767"(positive regulation of cytoplasmic translation)|interpro:IPR001878(Zinc finger, CCHC-type)|interpro:IPR036875|mint:P53996|refseq:NP_001334254.1	-	chain-seq-start:60|chain-seq-end:166	-	figure legend:ST1.2|comment:DTT-eluted fraction|dataset:Rare diseases - Interactions investigated in the context of Rare genetic disease|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2020/12/04	2020/12/21	rogid:mvYK6+YgIN/WuGLBCWqsqPLfDyQ10090	rogid:qXoAcOW8P42Ch0udEU00YlhTgn810090	rigid:sUlyHN3eQirg+yWIik/3UpGEVS4	false	mutation:34-34	-	-	-	psi-mi:"MI:0082"(peptide massfingerprinting)	psi-mi:"MI:0082"(peptide massfingerprinting)
uniprotkb:P97493-PRO_0000034151	uniprotkb:Q9DAW9	intact:EBI-26567598	intact:EBI-309337|uniprotkb:Q3TW23|ensembl:ENSMUSP00000029773	psi-mi:p97493-pro_0000034151(display_long)|uniprotkb:Thioredoxin-2(gene name synonym)|uniprotkb:Txn2(gene name)|psi-mi:Txn2(display_short)	psi-mi:cnn3_mouse(display_long)|uniprotkb:Cnn3(gene name)|psi-mi:Cnn3(display_short)|uniprotkb:Calponin, acidic isoform(gene name synonym)	psi-mi:"MI:0096"(pull down)	Chasapis et al. (2019)	pubmed:31018154|imex:IM-28571	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26499997|imex:IM-28571-41	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	intact:EBI-8354432(chain-parent)	refseq:NP_082320.1|ensembl:ENSMUSG00000053931(gene)|ensembl:ENSMUST00000029773(transcript)|go:"GO:0003779"(actin binding)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005829"(cytosol)|go:"GO:0008017"(microtubule binding)|go:"GO:0014069"(postsynaptic density)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0030425"(dendrite)|go:"GO:0030855"(epithelial cell differentiation)|go:"GO:0031032"(actomyosin structure organization)|go:"GO:0032780"(negative regulation of ATP-dependent activity)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043197"(dendritic spine)|interpro:IPR000557(Calponin repeat)|interpro:IPR001715(Calponin-like actin-binding)|interpro:IPR001997(Calponin)|interpro:IPR003096(SM22/calponin)|interpro:IPR036872|mint:Q9DAW9	-	chain-seq-start:60|chain-seq-end:166	-	figure legend:ST1.2|comment:DTT-eluted fraction|dataset:Rare diseases - Interactions investigated in the context of Rare genetic disease|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2020/12/04	2020/12/21	rogid:mvYK6+YgIN/WuGLBCWqsqPLfDyQ10090	rogid:cn+rHAOQedU+3wMhUjo4gJugQyo10090	rigid:sUlyHN3eQirg+yWIik/3UpGEVS4	false	mutation:34-34	-	-	-	psi-mi:"MI:0082"(peptide massfingerprinting)	psi-mi:"MI:0082"(peptide massfingerprinting)
uniprotkb:P97493-PRO_0000034151	uniprotkb:P19973	intact:EBI-26567598	intact:EBI-527499|uniprotkb:P97339|uniprotkb:Q04950|uniprotkb:Q62022|uniprotkb:Q62023|uniprotkb:Q62024|uniprotkb:Q8CD28|uniprotkb:Q99L65|uniprotkb:A2A6J5|uniprotkb:A2A6J6|ensembl:ENSMUSP00000018963|ensembl:ENSMUSP00000101588	psi-mi:p97493-pro_0000034151(display_long)|uniprotkb:Thioredoxin-2(gene name synonym)|uniprotkb:Txn2(gene name)|psi-mi:Txn2(display_short)	psi-mi:lsp1_mouse(display_long)|uniprotkb:52 kDa phosphoprotein(gene name synonym)|uniprotkb:Lymphocyte-specific antigen WP34(gene name synonym)|uniprotkb:S37 protein(gene name synonym)|uniprotkb:Lsp1(gene name)|psi-mi:Lsp1(display_short)|uniprotkb:Pp52(gene name synonym)|uniprotkb:S37(gene name synonym)|uniprotkb:Wp34(gene name synonym)	psi-mi:"MI:0096"(pull down)	Chasapis et al. (2019)	pubmed:31018154|imex:IM-28571	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26499997|imex:IM-28571-41	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	intact:EBI-8354432(chain-parent)	refseq:NP_001258437.1|refseq:NP_001258439.1|refseq:NP_001129543.1|refseq:NP_062264.1|ensembl:ENSMUSG00000018819(gene)|ensembl:ENSMUST00000018963(transcript)|ensembl:ENSMUST00000105968(transcript)|go:"GO:0003779"(actin binding)|go:"GO:0005886"(plasma membrane)|go:"GO:0006915"(apoptotic process)|go:"GO:0006935"(chemotaxis)|go:"GO:0006952"(defense response)|go:"GO:0007010"(cytoskeleton organization)|go:"GO:0007165"(signal transduction)|go:"GO:0098761"(cellular response to interleukin-7)|interpro:IPR002211(Lymphocyte-specific protein)|interpro:IPR006018(Caldesmon and lymphocyte specific protein)|mint:P19973	-	chain-seq-start:60|chain-seq-end:166	-	figure legend:ST1.2|comment:DTT-eluted fraction|dataset:Rare diseases - Interactions investigated in the context of Rare genetic disease|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2020/12/04	2020/12/21	rogid:mvYK6+YgIN/WuGLBCWqsqPLfDyQ10090	rogid:z1O5bTtKNXWpE7NpZK5XiSCowps10090	rigid:sUlyHN3eQirg+yWIik/3UpGEVS4	false	mutation:34-34	-	-	-	psi-mi:"MI:0082"(peptide massfingerprinting)	psi-mi:"MI:0082"(peptide massfingerprinting)
uniprotkb:P97493-PRO_0000034151	uniprotkb:P06151	intact:EBI-26567598	intact:EBI-444940|ensembl:ENSMUSP00000036386|ensembl:ENSMUSP00000103267	psi-mi:p97493-pro_0000034151(display_long)|uniprotkb:Thioredoxin-2(gene name synonym)|uniprotkb:Txn2(gene name)|psi-mi:Txn2(display_short)	psi-mi:ldha_mouse(display_long)|uniprotkb:LDH muscle subunit(gene name synonym)|uniprotkb:Ldha(gene name)|psi-mi:Ldha(display_short)|uniprotkb:Ldh-1(gene name synonym)|uniprotkb:Ldh1(gene name synonym)	psi-mi:"MI:0096"(pull down)	Chasapis et al. (2019)	pubmed:31018154|imex:IM-28571	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26500005|imex:IM-28571-43	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	intact:EBI-8354432(chain-parent)	refseq:NP_034829.1|ensembl:ENSMUSG00000063229(gene)|ensembl:ENSMUST00000005051(transcript)|ensembl:ENSMUST00000048209(transcript)|go:"GO:0004457"(lactate dehydrogenase activity)|go:"GO:0004459"(L-lactate dehydrogenase activity)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0019244"(lactate biosynthetic process from pyruvate)|go:"GO:0019661"(glucose catabolic process to lactate via pyruvate)|go:"GO:0031668"(cellular response to extracellular stimulus)|go:"GO:0035686"(sperm fibrous sheath)|go:"GO:0042802"(identical protein binding)|interpro:IPR001236(Lactate/malate dehydrogenase)|interpro:IPR001557(L-lactate/malate dehydrogenase)|interpro:IPR011304(L-lactate dehydrogenase)|interpro:IPR015955(Lactate dehydrogenase/glycoside hydrolase, family 4, C-terminal)|interpro:IPR018177|interpro:IPR022383|interpro:IPR036291|mint:P06151|reactome:R-MMU-70268	-	chain-seq-start:60|chain-seq-end:166	-	figure legend:ST1.3|comment:acid-eluted fraction|dataset:Rare diseases - Interactions investigated in the context of Rare genetic disease|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2020/12/04	2020/12/21	rogid:mvYK6+YgIN/WuGLBCWqsqPLfDyQ10090	rogid:IErFuOIWq53/XyIxWgUyVi76VnM10090	rigid:2GOxg3PEbB4/d/naM3ax5e8q84s	false	mutation:34-34	-	-	-	psi-mi:"MI:0082"(peptide massfingerprinting)	psi-mi:"MI:0082"(peptide massfingerprinting)
uniprotkb:P97493-PRO_0000034151	uniprotkb:P05064	intact:EBI-26567598	intact:EBI-494220|ensembl:ENSMUSP00000032934|ensembl:ENSMUSP00000101955	psi-mi:p97493-pro_0000034151(display_long)|uniprotkb:Thioredoxin-2(gene name synonym)|uniprotkb:Txn2(gene name)|psi-mi:Txn2(display_short)	psi-mi:aldoa_mouse(display_long)|uniprotkb:Muscle-type aldolase(gene name synonym)|uniprotkb:Aldolase 1(gene name synonym)|uniprotkb:Aldoa(gene name)|psi-mi:Aldoa(display_short)|uniprotkb:Aldo1(gene name synonym)	psi-mi:"MI:0096"(pull down)	Chasapis et al. (2019)	pubmed:31018154|imex:IM-28571	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26500005|imex:IM-28571-43	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	intact:EBI-8354432(chain-parent)	refseq:XP_006507273.1|refseq:XP_006507274.1|refseq:NP_001170779.1|refseq:NP_031464.1|go:"GO:0006000"(fructose metabolic process)|go:"GO:0006096"(glycolytic process)|go:"GO:0006754"(ATP biosynthetic process)|go:"GO:0006941"(striated muscle contraction)|go:"GO:0007339"(binding of sperm to zona pellucida)|go:"GO:0008092"(cytoskeletal protein binding)|go:"GO:0008360"(regulation of cell shape)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0016020"(membrane)|go:"GO:0019242"(methylglyoxal biosynthetic process)|go:"GO:0030018"(Z disc)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0030388"(fructose 1,6-bisphosphate metabolic process)|go:"GO:0031430"(M band)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035686"(sperm fibrous sheath)|go:"GO:0042802"(identical protein binding)|go:"GO:0043209"(myelin sheath)|go:"GO:0046716"(muscle cell cellular homeostasis)|go:"GO:0051289"(protein homotetramerization)|go:"GO:0061615"(glycolytic process through fructose-6-phosphate)|go:"GO:0061827"(sperm head)|go:"GO:0005886"(plasma membrane)|go:"GO:0070061"(fructose binding)|go:"GO:0070062"(extracellular exosome)|interpro:IPR000741(Fructose-bisphosphate aldolase, class-I)|interpro:IPR013785(Aldolase-type TIM barrel)|ensembl:ENSMUSG00000030695(gene)|ensembl:ENSMUST00000032934(transcript)|ensembl:ENSMUST00000106348(transcript)|go:"GO:0000792"(heterochromatin)|go:"GO:0002020"(protease binding)|go:"GO:0004332"(fructose-bisphosphate aldolase activity)|go:"GO:0005615"(extracellular space)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|mint:P05064|reactome:R-MMU-114608|reactome:R-MMU-6798695|reactome:R-MMU-70171|reactome:R-MMU-70263|interpro:IPR029768	-	chain-seq-start:60|chain-seq-end:166	-	figure legend:ST1.3|comment:acid-eluted fraction|dataset:Rare diseases - Interactions investigated in the context of Rare genetic disease|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2020/12/04	2020/12/21	rogid:mvYK6+YgIN/WuGLBCWqsqPLfDyQ10090	rogid:m116/AX8vWkh1JCGOnEZv9ZOU9010090	rigid:2GOxg3PEbB4/d/naM3ax5e8q84s	false	mutation:34-34	-	-	-	psi-mi:"MI:0082"(peptide massfingerprinting)	psi-mi:"MI:0082"(peptide massfingerprinting)
uniprotkb:P97493-PRO_0000034151	uniprotkb:P07310	intact:EBI-26567598	intact:EBI-299493|ensembl:ENSMUSP00000146972	psi-mi:p97493-pro_0000034151(display_long)|uniprotkb:Thioredoxin-2(gene name synonym)|uniprotkb:Txn2(gene name)|psi-mi:Txn2(display_short)	psi-mi:kcrm_mouse(display_long)|uniprotkb:Ckm(gene name)|psi-mi:Ckm(display_short)|uniprotkb:Ckmm(gene name synonym)|uniprotkb:Creatine kinase M chain(gene name synonym)|uniprotkb:M-CK(gene name synonym)|uniprotkb:Creatine phosphokinase M-type(gene name synonym)	psi-mi:"MI:0096"(pull down)	Chasapis et al. (2019)	pubmed:31018154|imex:IM-28571	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26500005|imex:IM-28571-43	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	intact:EBI-8354432(chain-parent)	ensembl:ENSMUSG00000030399(gene)|ensembl:ENSMUST00000208710(transcript)|go:"GO:0004111"(creatine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005737"(cytoplasm)|go:"GO:0006603"(phosphocreatine metabolic process)|go:"GO:0009408"(response to heat)|go:"GO:0016301"(kinase activity)|go:"GO:0046314"(phosphocreatine biosynthetic process)|interpro:IPR000749("ATP:guanido phosphotransferase")|interpro:IPR014746(Glutamine synthetase/guanido kinase, catalytic region)|interpro:IPR022413|interpro:IPR022414|interpro:IPR022415|interpro:IPR036802|mint:P07310|reactome:R-MMU-71288|refseq:NP_031736.1	-	chain-seq-start:60|chain-seq-end:166	-	figure legend:ST1.3|comment:acid-eluted fraction|dataset:Rare diseases - Interactions investigated in the context of Rare genetic disease|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2020/12/04	2020/12/21	rogid:mvYK6+YgIN/WuGLBCWqsqPLfDyQ10090	rogid:HUwtOLpKEeqrxa326Rz+yjZ6/Mo10090	rigid:2GOxg3PEbB4/d/naM3ax5e8q84s	false	mutation:34-34	-	-	-	psi-mi:"MI:0082"(peptide massfingerprinting)	psi-mi:"MI:0082"(peptide massfingerprinting)
uniprotkb:P97493-PRO_0000034151	uniprotkb:P21550	intact:EBI-26567598	intact:EBI-1634301|ensembl:ENSMUSP00000072620|ensembl:ENSMUSP00000104188|ensembl:ENSMUSP00000128714	psi-mi:p97493-pro_0000034151(display_long)|uniprotkb:Thioredoxin-2(gene name synonym)|uniprotkb:Txn2(gene name)|psi-mi:Txn2(display_short)	psi-mi:enob_mouse(display_long)|uniprotkb:Eno3(gene name)|psi-mi:Eno3(display_short)|uniprotkb:Eno-3(gene name synonym)|uniprotkb:2-phospho-D-glycerate hydro-lyase(gene name synonym)|uniprotkb:Muscle-specific enolase(gene name synonym)|uniprotkb:Skeletal muscle enolase(gene name synonym)|uniprotkb:Enolase 3(gene name synonym)	psi-mi:"MI:0096"(pull down)	Chasapis et al. (2019)	pubmed:31018154|imex:IM-28571	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26500005|imex:IM-28571-43	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	intact:EBI-8354432(chain-parent)	refseq:NP_001129534.1|refseq:NP_031959.1|refseq:NP_001263214.1|refseq:XP_006532225.1|ensembl:ENSMUSG00000060600(gene)|ensembl:ENSMUST00000072841(transcript)|ensembl:ENSMUST00000108548(transcript)|ensembl:ENSMUST00000170716(transcript)|go:"GO:0000015"(phosphopyruvate hydratase complex)|go:"GO:0000287"(magnesium ion binding)|go:"GO:0004634"(phosphopyruvate hydratase activity)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006096"(glycolytic process)|go:"GO:0007568"(aging)|go:"GO:0016020"(membrane)|go:"GO:0032889"(regulation of vacuole fusion, non-autophagic)|go:"GO:0042493"|go:"GO:0042802"(identical protein binding)|go:"GO:0043403"(skeletal muscle tissue regeneration)|go:"GO:0044877"(protein-containing complex binding)|interpro:IPR000941(Enolase)|interpro:IPR020809|interpro:IPR020810|interpro:IPR020811|interpro:IPR029017|interpro:IPR036849|mint:P21550|reactome:R-MMU-70171|reactome:R-MMU-70263	-	chain-seq-start:60|chain-seq-end:166	-	figure legend:ST1.3|comment:acid-eluted fraction|dataset:Rare diseases - Interactions investigated in the context of Rare genetic disease|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2020/12/04	2020/12/21	rogid:mvYK6+YgIN/WuGLBCWqsqPLfDyQ10090	rogid:CN/5EMhCFqpjAxZ04UHwcLN+eRI10090	rigid:2GOxg3PEbB4/d/naM3ax5e8q84s	false	mutation:34-34	-	-	-	psi-mi:"MI:0082"(peptide massfingerprinting)	psi-mi:"MI:0082"(peptide massfingerprinting)
uniprotkb:P97493-PRO_0000034151	uniprotkb:P56480	intact:EBI-26567598	intact:EBI-299482|ensembl:ENSMUSP00000026459|uniprotkb:Q0QEP4|uniprotkb:Q3TFD7|uniprotkb:Q3TIP9|uniprotkb:Q3TK44|uniprotkb:Q3TWD5|uniprotkb:Q3TX28|uniprotkb:Q3U6U4|uniprotkb:Q3U774|uniprotkb:Q3UB69|uniprotkb:Q3UF69|uniprotkb:Q8CI65|uniprotkb:Q8VEJ5|uniprotkb:Q9CTI7|uniprotkb:Q9CWX7	psi-mi:p97493-pro_0000034151(display_long)|uniprotkb:Thioredoxin-2(gene name synonym)|uniprotkb:Txn2(gene name)|psi-mi:Txn2(display_short)	psi-mi:atpb_mouse(display_long)|uniprotkb:Atp5f1b(gene name)|psi-mi:Atp5f1b(display_short)|uniprotkb:ATP synthase F1 subunit beta(gene name synonym)|uniprotkb:Atp5b(gene name synonym)	psi-mi:"MI:0096"(pull down)	Chasapis et al. (2019)	pubmed:31018154|imex:IM-28571	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26500005|imex:IM-28571-43	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	intact:EBI-8354432(chain-parent)	interpro:IPR024034|interpro:IPR027417|interpro:IPR036121|mint:P56480|reactome:R-MMU-1268020|reactome:R-MMU-163210|reactome:R-MMU-8949613|interpro:IPR020003|ensembl:ENSMUSG00000025393(gene)|ensembl:ENSMUST00000026459(transcript)|go:"GO:0000275"("mitochondrial proton-transporting ATP synthase complex, catalytic sector F(1)")|go:"GO:0001525"(angiogenesis)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005753"(mitochondrial proton-transporting ATP synthase complex)|go:"GO:0005886"(plasma membrane)|go:"GO:0006629"(lipid metabolic process)|go:"GO:0006754"(ATP biosynthetic process)|go:"GO:0006898"(receptor-mediated endocytosis)|go:"GO:0006933"(negative regulation of cell adhesion involved in substrate-bound cell migration)|go:"GO:0009986"(cell surface)|go:"GO:0016020"(membrane)|go:"GO:0030228"(lipoprotein particle receptor activity)|go:"GO:0031966"(mitochondrial membrane)|go:"GO:0042288"(MHC class I protein binding)|go:"GO:0042645"(mitochondrial nucleoid)|go:"GO:0042776"(mitochondrial ATP synthesis coupled proton transport)|go:"GO:0043209"(myelin sheath)|go:"GO:0043531"(ADP binding)|go:"GO:0043532"(angiostatin binding)|go:"GO:0043536"(positive regulation of blood vessel endothelial cell migration)|go:"GO:0045121"(membrane raft)|go:"GO:0045259"(proton-transporting ATP synthase complex)|go:"GO:0045261"("proton-transporting ATP synthase complex, catalytic core F(1)")|go:"GO:0046034"(ATP metabolic process)|go:"GO:0046933"(proton-transporting ATP synthase activity, rotational mechanism)|go:"GO:0046961"(proton-transporting ATPase activity, rotational mechanism)|go:"GO:0051453"(regulation of intracellular pH)|go:"GO:0098761"(cellular response to interleukin-7)|go:"GO:1902600"(proton transmembrane transport)|interpro:IPR000194(ATPase, F1/V1/A1 complex, alpha/beta subunit, nucleotide-binding)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR004100(ATPase, F1/V1/A1 complex, alpha/beta subunit, N-terminal)|interpro:IPR005722(ATPase, F1 complex, beta subunit)|go:"GO:0005524"(ATP binding)|refseq:NP_058054.2	-	chain-seq-start:60|chain-seq-end:166	-	figure legend:ST1.3|comment:acid-eluted fraction|dataset:Rare diseases - Interactions investigated in the context of Rare genetic disease|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2020/12/04	2020/12/21	rogid:mvYK6+YgIN/WuGLBCWqsqPLfDyQ10090	rogid:ihjn7GQ1ZSBfGcfwEAYSiCIuq+410090	rigid:2GOxg3PEbB4/d/naM3ax5e8q84s	false	mutation:34-34	-	-	-	psi-mi:"MI:0082"(peptide massfingerprinting)	psi-mi:"MI:0082"(peptide massfingerprinting)
uniprotkb:P97493-PRO_0000034151	uniprotkb:Q03265	intact:EBI-26567598	intact:EBI-299884|ensembl:ENSMUSP00000026495|uniprotkb:Q3TFN0|uniprotkb:Q3THN8|uniprotkb:Q3TPR0|uniprotkb:Q3TPV3|uniprotkb:Q3TZU3|uniprotkb:Q3UIR7|uniprotkb:Q543Y6	psi-mi:p97493-pro_0000034151(display_long)|uniprotkb:Thioredoxin-2(gene name synonym)|uniprotkb:Txn2(gene name)|psi-mi:Txn2(display_short)	psi-mi:atpa_mouse(display_long)|uniprotkb:Atp5f1a(gene name)|psi-mi:Atp5f1a(display_short)|uniprotkb:ATP synthase F1 subunit alpha(gene name synonym)|uniprotkb:Atp5a1(gene name synonym)	psi-mi:"MI:0096"(pull down)	Chasapis et al. (2019)	pubmed:31018154|imex:IM-28571	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26500005|imex:IM-28571-43	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	intact:EBI-8354432(chain-parent)	go:"GO:0005634"(nucleus)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005753"(mitochondrial proton-transporting ATP synthase complex)|ensembl:ENSMUSG00000025428(gene)|ensembl:ENSMUST00000026495(transcript)|go:"GO:0000275"("mitochondrial proton-transporting ATP synthase complex, catalytic sector F(1)")|go:"GO:0001937"(negative regulation of endothelial cell proliferation)|go:"GO:0002020"(protease binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005754"(mitochondrial proton-transporting ATP synthase, catalytic core)|go:"GO:0005886"(plasma membrane)|go:"GO:0006629"(lipid metabolic process)|go:"GO:0006754"(ATP biosynthetic process)|go:"GO:0008180"(COP9 signalosome)|go:"GO:0009986"(cell surface)|go:"GO:0015986"(ATP synthesis coupled proton transport)|go:"GO:0016020"(membrane)|go:"GO:0042288"(MHC class I protein binding)|go:"GO:0042776"(mitochondrial ATP synthesis coupled proton transport)|go:"GO:0043209"(myelin sheath)|go:"GO:0043531"(ADP binding)|go:"GO:0043532"(angiostatin binding)|go:"GO:0043536"(positive regulation of blood vessel endothelial cell migration)|go:"GO:0045121"(membrane raft)|go:"GO:0045259"(proton-transporting ATP synthase complex)|go:"GO:0045261"("proton-transporting ATP synthase complex, catalytic core F(1)")|go:"GO:0046034"(ATP metabolic process)|go:"GO:0046933"(proton-transporting ATP synthase activity, rotational mechanism)|interpro:IPR000194(ATPase, F1/V1/A1 complex, alpha/beta subunit, nucleotide-binding)|interpro:IPR000793(ATPase, F1/V1/A1 complex, alpha/beta subunit, C-terminal)|interpro:IPR004100(ATPase, F1/V1/A1 complex, alpha/beta subunit, N-terminal)|interpro:IPR005294(ATPase, F1 complex, alpha subunit)|interpro:IPR020003|interpro:IPR023366|interpro:IPR027417|interpro:IPR033732|interpro:IPR036121|interpro:IPR038376|mint:Q03265|reactome:R-MMU-163210|reactome:R-MMU-8949613|refseq:NP_031531.1	-	chain-seq-start:60|chain-seq-end:166	-	figure legend:ST1.3|comment:acid-eluted fraction|dataset:Rare diseases - Interactions investigated in the context of Rare genetic disease|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2020/12/04	2020/12/21	rogid:mvYK6+YgIN/WuGLBCWqsqPLfDyQ10090	rogid:sBPTQwqC0dJTjZlZMKRzTSu6gHg10090	rigid:2GOxg3PEbB4/d/naM3ax5e8q84s	false	mutation:34-34	-	-	-	psi-mi:"MI:0082"(peptide massfingerprinting)	psi-mi:"MI:0082"(peptide massfingerprinting)
uniprotkb:P97493-PRO_0000034151	uniprotkb:P23927	intact:EBI-26567598	intact:EBI-299046|ensembl:ENSMUSP00000034562|ensembl:ENSMUSP00000149759|ensembl:ENSMUSP00000149803|ensembl:ENSMUSP00000150669|uniprotkb:Q64325	psi-mi:p97493-pro_0000034151(display_long)|uniprotkb:Thioredoxin-2(gene name synonym)|uniprotkb:Txn2(gene name)|psi-mi:Txn2(display_short)	psi-mi:cryab_mouse(display_long)|uniprotkb:Cryab(gene name)|psi-mi:Cryab(display_short)|uniprotkb:Crya2(gene name synonym)|uniprotkb:"Alpha(B)-crystallin"(gene name synonym)|uniprotkb:P23(gene name synonym)	psi-mi:"MI:0096"(pull down)	Chasapis et al. (2019)	pubmed:31018154|imex:IM-28571	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26500005|imex:IM-28571-43	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	intact:EBI-8354432(chain-parent)	ensembl:ENSMUSG00000032060(gene)|ensembl:ENSMUST00000034562(transcript)|ensembl:ENSMUST00000214962(transcript)|ensembl:ENSMUST00000216755(transcript)|ensembl:ENSMUST00000217475(transcript)|go:"GO:0001540"(amyloid-beta binding)|go:"GO:0001666"(response to hypoxia)|go:"GO:0002088"(lens development in camera-type eye)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005212"(structural constituent of eye lens)|go:"GO:0005576"(extracellular region)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006457"(protein folding)|go:"GO:0007021"(tubulin complex assembly)|go:"GO:0007517"(muscle organ development)|go:"GO:0008017"(microtubule binding)|go:"GO:0008092"(cytoskeletal protein binding)|go:"GO:0009986"(cell surface)|go:"GO:0010259"(multicellular organism aging)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0010941"(regulation of cell death)|go:"GO:0014069"(postsynaptic density)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0030018"(Z disc)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0030424"(axon)|go:"GO:0031109"(microtubule polymerization or depolymerization)|go:"GO:0031333"(negative regulation of protein-containing complex assembly)|go:"GO:0031430"(M band)|go:"GO:0031674"(I band)|go:"GO:0032355"(response to estradiol)|go:"GO:0032387"(negative regulation of intracellular transport)|go:"GO:0032432"(actin filament bundle)|go:"GO:0032991"(protein-containing complex)|go:"GO:0042542"(response to hydrogen peroxide)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043010"(camera-type eye development)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043154"(negative regulation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0043197"(dendritic spine)|go:"GO:0043204"(perikaryon)|go:"GO:0043209"(myelin sheath)|go:"GO:0043292"(contractile fiber)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045202"(synapse)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0046872"(metal ion binding)|go:"GO:0050821"(protein stabilization)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0051403"(stress-activated MAPK cascade)|go:"GO:0060561"(apoptotic process involved in morphogenesis)|go:"GO:0071480"(cellular response to gamma radiation)|go:"GO:0097060"(synaptic membrane)|go:"GO:0097512"(cardiac myofibril)|go:"GO:1905907"(negative regulation of amyloid fibril formation)|go:"GO:2000378"(negative regulation of reactive oxygen species metabolic process)|interpro:IPR001436(Alpha crystallin/Heat shock protein)|interpro:IPR002068(Heat shock protein Hsp20)|interpro:IPR003090(Alpha-crystallin, N-terminal)|interpro:IPR008978(HSP20-like chaperone)|interpro:IPR037882|mint:P23927|reactome:R-MMU-3371571|refseq:XP_006510033.1|refseq:NP_034094.1|refseq:NP_001276711.1|refseq:NP_001276713.1|refseq:NP_001276714.1|dip:DIP-31060N	-	chain-seq-start:60|chain-seq-end:166	-	figure legend:ST1.3|comment:acid-eluted fraction|dataset:Rare diseases - Interactions investigated in the context of Rare genetic disease|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2020/12/04	2020/12/21	rogid:mvYK6+YgIN/WuGLBCWqsqPLfDyQ10090	rogid:LOp5smbeRceV8/P+Eaoh7p+24Vw10090	rigid:2GOxg3PEbB4/d/naM3ax5e8q84s	false	mutation:34-34	-	-	-	psi-mi:"MI:0082"(peptide massfingerprinting)	psi-mi:"MI:0082"(peptide massfingerprinting)
uniprotkb:P97493-PRO_0000034151	uniprotkb:P62737	intact:EBI-26567598	intact:EBI-5297932|uniprotkb:P03996|uniprotkb:P04108|ensembl:ENSMUSP00000048218	psi-mi:p97493-pro_0000034151(display_long)|uniprotkb:Thioredoxin-2(gene name synonym)|uniprotkb:Txn2(gene name)|psi-mi:Txn2(display_short)	psi-mi:acta_mouse(display_long)|uniprotkb:Acta2(gene name)|psi-mi:Acta2(display_short)|uniprotkb:Actsa(gene name synonym)|uniprotkb:Actvs(gene name synonym)|uniprotkb:Alpha-actin-2(gene name synonym)	psi-mi:"MI:0096"(pull down)	Chasapis et al. (2019)	pubmed:31018154|imex:IM-28571	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26500005|imex:IM-28571-43	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	intact:EBI-8354432(chain-parent)	refseq:NP_031418.1|ensembl:ENSMUSG00000035783(gene)|ensembl:ENSMUST00000039631(transcript)|go:"GO:0001725"(stress fiber)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005869"(dynactin complex)|go:"GO:0006936"(muscle contraction)|go:"GO:0008217"(regulation of blood pressure)|go:"GO:0009615"(response to virus)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0014829"(vascular associated smooth muscle contraction)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030027"(lamellipodium)|go:"GO:0030175"(filopodium)|go:"GO:0030485"(smooth muscle contractile fiber)|go:"GO:0044297"(cell body)|go:"GO:0061041"(regulation of wound healing)|go:"GO:0061870"(positive regulation of hepatic stellate cell migration)|go:"GO:0061874"(positive regulation of hepatic stellate cell contraction)|go:"GO:0070374"(positive regulation of ERK1 and ERK2 cascade)|go:"GO:0072144"(glomerular mesangial cell development)|go:"GO:0090131"(mesenchyme migration)|go:"GO:2000491"(positive regulation of hepatic stellate cell activation)|interpro:IPR004000(Actin/actin-like)|interpro:IPR004001(Actin, conserved site)|interpro:IPR020902|interpro:IPR043129|mint:P62737|reactome:R-MMU-445355	-	chain-seq-start:60|chain-seq-end:166	-	figure legend:ST1.3|comment:acid-eluted fraction|dataset:Rare diseases - Interactions investigated in the context of Rare genetic disease|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2020/12/04	2020/12/21	rogid:mvYK6+YgIN/WuGLBCWqsqPLfDyQ10090	rogid:mRZGUdL/jBuj6nVHtxoasZuA7yA10090	rigid:2GOxg3PEbB4/d/naM3ax5e8q84s	false	mutation:34-34	-	-	-	psi-mi:"MI:0082"(peptide massfingerprinting)	psi-mi:"MI:0082"(peptide massfingerprinting)
uniprotkb:P97493-PRO_0000034151	uniprotkb:P68134	intact:EBI-26567598	intact:EBI-367520|uniprotkb:P02568|uniprotkb:P99020|ensembl:ENSMUSP00000034453	psi-mi:p97493-pro_0000034151(display_long)|uniprotkb:Thioredoxin-2(gene name synonym)|uniprotkb:Txn2(gene name)|psi-mi:Txn2(display_short)	psi-mi:acts_mouse(display_long)|uniprotkb:Acta1(gene name)|psi-mi:Acta1(display_short)|uniprotkb:Acta(gene name synonym)|uniprotkb:Alpha-actin-1(gene name synonym)	psi-mi:"MI:0096"(pull down)	Chasapis et al. (2019)	pubmed:31018154|imex:IM-28571	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26500005|imex:IM-28571-43	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	intact:EBI-8354432(chain-parent)	refseq:NP_033736.1|ensembl:ENSMUSG00000031972(gene)|ensembl:ENSMUST00000034453(transcript)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005865"(striated muscle thin filament)|go:"GO:0005869"(dynactin complex)|go:"GO:0005884"(actin filament)|go:"GO:0009612"(response to mechanical stimulus)|go:"GO:0009991"(response to extracellular stimulus)|go:"GO:0010226"(response to lithium ion)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0030017"(sarcomere)|go:"GO:0030027"(lamellipodium)|go:"GO:0030175"(filopodium)|go:"GO:0030240"(skeletal muscle thin filament assembly)|go:"GO:0032991"(protein-containing complex)|go:"GO:0043503"(skeletal muscle fiber adaptation)|go:"GO:0044297"(cell body)|go:"GO:0048545"(response to steroid hormone)|go:"GO:0048741"(skeletal muscle fiber development)|go:"GO:0071417"(cellular response to organonitrogen compound)|go:"GO:0090131"(mesenchyme migration)|interpro:IPR004000(Actin/actin-like)|interpro:IPR004001(Actin, conserved site)|interpro:IPR020902|interpro:IPR043129|mint:P68134|rcsb pdb:4B1U|rcsb pdb:6KLL|rcsb pdb:6KLN|rcsb pdb:7AQK|rcsb pdb:7NEP|reactome:R-MMU-390522|go:"GO:0001725"(stress fiber)|refseq:NP_001258970.1	-	chain-seq-start:60|chain-seq-end:166	-	figure legend:ST1.3|comment:acid-eluted fraction|dataset:Rare diseases - Interactions investigated in the context of Rare genetic disease|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2020/12/04	2020/12/21	rogid:mvYK6+YgIN/WuGLBCWqsqPLfDyQ10090	rogid:2vZu8ElmMe+6GjKBliCAatNGZR410090	rigid:2GOxg3PEbB4/d/naM3ax5e8q84s	false	mutation:34-34	-	-	-	psi-mi:"MI:0082"(peptide massfingerprinting)	psi-mi:"MI:0082"(peptide massfingerprinting)
uniprotkb:P97493-PRO_0000034151	uniprotkb:P17751	intact:EBI-26567598	intact:EBI-444877|uniprotkb:Q3TJH2|uniprotkb:Q3UC04|uniprotkb:Q3UKG9|uniprotkb:Q64513|uniprotkb:Q9CVF9|uniprotkb:Q9CWE7|ensembl:ENSMUSP00000130858	psi-mi:p97493-pro_0000034151(display_long)|uniprotkb:Thioredoxin-2(gene name synonym)|uniprotkb:Txn2(gene name)|psi-mi:Txn2(display_short)	psi-mi:tpis_mouse(display_long)|uniprotkb:Triose-phosphate isomerase(gene name synonym)|uniprotkb:Tpi1(gene name)|psi-mi:Tpi1(display_short)|uniprotkb:Tpi(gene name synonym)|uniprotkb:Methylglyoxal synthase(gene name synonym)	psi-mi:"MI:0096"(pull down)	Chasapis et al. (2019)	pubmed:31018154|imex:IM-28571	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26500005|imex:IM-28571-43	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	intact:EBI-8354432(chain-parent)	refseq:NP_033441.2|ensembl:ENSMUSG00000023456(gene)|ensembl:ENSMUST00000172132(transcript)|go:"GO:0004807"(triose-phosphate isomerase activity)|go:"GO:0005829"(cytosol)|go:"GO:0006006"(glucose metabolic process)|go:"GO:0006094"(gluconeogenesis)|go:"GO:0006096"(glycolytic process)|go:"GO:0008929"(methylglyoxal synthase activity)|go:"GO:0016853"(isomerase activity)|go:"GO:0019242"(methylglyoxal biosynthetic process)|go:"GO:0019563"(glycerol catabolic process)|go:"GO:0019682"(glyceraldehyde-3-phosphate metabolic process)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0046166"(glyceraldehyde-3-phosphate biosynthetic process)|interpro:IPR000652(Triosephosphate isomerase)|interpro:IPR013785(Aldolase-type TIM barrel)|interpro:IPR020861|interpro:IPR022896|interpro:IPR035990|mint:P17751|reactome:R-MMU-70171|reactome:R-MMU-70263	-	chain-seq-start:60|chain-seq-end:166	-	figure legend:ST1.3|comment:acid-eluted fraction|dataset:Rare diseases - Interactions investigated in the context of Rare genetic disease|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2020/12/04	2020/12/21	rogid:mvYK6+YgIN/WuGLBCWqsqPLfDyQ10090	rogid:1+uasFpsjnuX50Ti23iaIawdp7k10090	rigid:2GOxg3PEbB4/d/naM3ax5e8q84s	false	mutation:34-34	-	-	-	psi-mi:"MI:0082"(peptide massfingerprinting)	psi-mi:"MI:0082"(peptide massfingerprinting)
uniprotkb:P97493-PRO_0000034151	uniprotkb:Q8K2B3	intact:EBI-26567598	intact:EBI-1219461|uniprotkb:Q0QF19|uniprotkb:Q3UH25|uniprotkb:Q3UKP7|uniprotkb:Q3V4B1|uniprotkb:Q921P5|uniprotkb:Q9Z1Z4|ensembl:ENSMUSP00000022062	psi-mi:p97493-pro_0000034151(display_long)|uniprotkb:Thioredoxin-2(gene name synonym)|uniprotkb:Txn2(gene name)|psi-mi:Txn2(display_short)	psi-mi:sdha_mouse(display_long)|uniprotkb:Sdha(gene name)|psi-mi:Sdha(display_short)|uniprotkb:Flavoprotein subunit of complex II(gene name synonym)	psi-mi:"MI:0096"(pull down)	Chasapis et al. (2019)	pubmed:31018154|imex:IM-28571	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26500005|imex:IM-28571-43	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	intact:EBI-8354432(chain-parent)	refseq:NP_075770.1|ensembl:ENSMUSG00000021577(gene)|ensembl:ENSMUST00000022062(transcript)|go:"GO:0000104"(succinate dehydrogenase activity)|go:"GO:0005730"(nucleolus)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005749"("mitochondrial respiratory chain complex II, succinate dehydrogenase complex (ubiquinone)")|go:"GO:0006099"(tricarboxylic acid cycle)|go:"GO:0006105"(succinate metabolic process)|go:"GO:0006121"(mitochondrial electron transport, succinate to ubiquinone)|go:"GO:0007399"(nervous system development)|go:"GO:0008177"("succinate dehydrogenase (ubiquinone) activity")|go:"GO:0009055"(electron transfer activity)|go:"GO:0022904"(respiratory electron transport chain)|go:"GO:0043209"(myelin sheath)|go:"GO:0050660"(flavin adenine dinucleotide binding)|interpro:IPR003952(Fumarate reductase/succinate dehydrogenase, FAD-binding site)|interpro:IPR003953(Fumarate reductase/succinate dehydrogenase flavoprotein, N-terminal)|interpro:IPR011281(Succinate dehydrogenase, flavoprotein subunit)|interpro:IPR014006(Succinate dehydrogenase or fumarate reductase, flavoprotein subunit)|interpro:IPR015939(Fumarate reductase/succinate dehydrogenase flavoprotein-like, C-terminal)|interpro:IPR027477|interpro:IPR036188|interpro:IPR037099|mint:Q8K2B3|reactome:R-MMU-71403	-	chain-seq-start:60|chain-seq-end:166	-	figure legend:ST1.3|comment:acid-eluted fraction|dataset:Rare diseases - Interactions investigated in the context of Rare genetic disease|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2020/12/04	2020/12/21	rogid:mvYK6+YgIN/WuGLBCWqsqPLfDyQ10090	rogid:DbI/pBVBwa3ezreOqH3hgGy1qkA10090	rigid:2GOxg3PEbB4/d/naM3ax5e8q84s	false	mutation:34-34	-	-	-	psi-mi:"MI:0082"(peptide massfingerprinting)	psi-mi:"MI:0082"(peptide massfingerprinting)
uniprotkb:P97493-PRO_0000034151	uniprotkb:Q91YT0	intact:EBI-26567598	intact:EBI-2934319|ensembl:ENSMUSP00000042967	psi-mi:p97493-pro_0000034151(display_long)|uniprotkb:Thioredoxin-2(gene name synonym)|uniprotkb:Txn2(gene name)|psi-mi:Txn2(display_short)	psi-mi:nduv1_mouse(display_long)|uniprotkb:Ndufv1(gene name)|psi-mi:Ndufv1(display_short)|uniprotkb:Complex I-51kD(gene name synonym)|uniprotkb:NADH-ubiquinone oxidoreductase 51 kDa subunit(gene name synonym)	psi-mi:"MI:0096"(pull down)	Chasapis et al. (2019)	pubmed:31018154|imex:IM-28571	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26500005|imex:IM-28571-43	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	intact:EBI-8354432(chain-parent)	ensembl:ENSMUSG00000037916(gene)|ensembl:ENSMUST00000042497(transcript)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005747"(mitochondrial respiratory chain complex I)|go:"GO:0005829"(cytosol)|go:"GO:0006120"(mitochondrial electron transport, NADH to ubiquinone)|go:"GO:0008137"("NADH dehydrogenase (ubiquinone) activity")|go:"GO:0010181"(FMN binding)|go:"GO:0046872"(metal ion binding)|go:"GO:0051287"(NAD binding)|go:"GO:0042775"(mitochondrial ATP synthesis coupled electron transport)|go:"GO:0051539"(4 iron, 4 sulfur cluster binding)|interpro:IPR001949(NADH-ubiquinone oxidoreductase, 51 kDa subunit, conserved site)|interpro:IPR011537(NADH-ubiquinone oxidoreductase, F subunit)|interpro:IPR011538(NADH-ubiquinone oxidoreductase, 51 kDa subunit)|interpro:IPR019554|interpro:IPR019575|interpro:IPR037207|interpro:IPR037225|mint:Q91YT0|rcsb pdb:6G2J|rcsb pdb:6G72|rcsb pdb:6ZR2|rcsb pdb:6ZTQ|rcsb pdb:7AK5|rcsb pdb:7AK6|rcsb pdb:7B93|reactome:R-MMU-611105|reactome:R-MMU-6799198|refseq:NP_598427.1	-	chain-seq-start:60|chain-seq-end:166	-	figure legend:ST1.3|comment:acid-eluted fraction|dataset:Rare diseases - Interactions investigated in the context of Rare genetic disease|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2020/12/04	2020/12/21	rogid:mvYK6+YgIN/WuGLBCWqsqPLfDyQ10090	rogid:xYJ5XxA1aRAaXMrlI8U+e9owOPU10090	rigid:2GOxg3PEbB4/d/naM3ax5e8q84s	false	mutation:34-34	-	-	-	psi-mi:"MI:0082"(peptide massfingerprinting)	psi-mi:"MI:0082"(peptide massfingerprinting)
uniprotkb:P97493-PRO_0000034151	uniprotkb:P14602	intact:EBI-26567598	intact:EBI-299023|ensembl:ENSMUSP00000005077	psi-mi:p97493-pro_0000034151(display_long)|uniprotkb:Thioredoxin-2(gene name synonym)|uniprotkb:Txn2(gene name)|psi-mi:Txn2(display_short)	psi-mi:hspb1_mouse(display_long)|uniprotkb:Hspb1(gene name)|psi-mi:Hspb1(display_short)|uniprotkb:Hsp25(gene name synonym)|uniprotkb:Hsp27(gene name synonym)|uniprotkb:Heat shock 27 kDa protein(gene name synonym)|uniprotkb:Heat shock 25 kDa protein(gene name synonym)|uniprotkb:Growth-related 25 kDa protein(gene name synonym)|uniprotkb:p25(gene name synonym)	psi-mi:"MI:0096"(pull down)	Chasapis et al. (2019)	pubmed:31018154|imex:IM-28571	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26500005|imex:IM-28571-43	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	intact:EBI-8354432(chain-parent)	ensembl:ENSMUSG00000004951(gene)|ensembl:ENSMUST00000005077(transcript)|go:"GO:0000502"(proteasome complex)|go:"GO:0001932"(regulation of protein phosphorylation)|go:"GO:0005080"(protein kinase C binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005819"(spindle)|go:"GO:0005886"(plasma membrane)|go:"GO:0006469"(negative regulation of protein kinase activity)|go:"GO:0006986"(response to unfolded protein)|go:"GO:0008426"(protein kinase C inhibitor activity)|go:"GO:0009615"(response to virus)|go:"GO:0010976"(positive regulation of neuron projection development)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030018"(Z disc)|go:"GO:0030424"(axon)|go:"GO:0030425"(dendrite)|go:"GO:0031430"(M band)|go:"GO:0031674"(I band)|go:"GO:0032731"(positive regulation of interleukin-1 beta production)|go:"GO:0032760"(positive regulation of tumor necrosis factor production)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0035924"(cellular response to vascular endothelial growth factor stimulus)|go:"GO:0038033"(positive regulation of endothelial cell chemotaxis by VEGF-activated vascular endothelial growth factor receptor signaling pathway)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043122"(regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043130"(ubiquitin binding)|go:"GO:0043204"(perikaryon)|go:"GO:0043292"(contractile fiber)|go:"GO:0043536"(positive regulation of blood vessel endothelial cell migration)|go:"GO:0044183"(protein folding chaperone)|go:"GO:0045202"(synapse)|go:"GO:0045590"(negative regulation of regulatory T cell differentiation)|go:"GO:0045766"(positive regulation of angiogenesis)|go:"GO:0061077"(chaperone-mediated protein folding)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:0097512"(cardiac myofibril)|go:"GO:0098839"(postsynaptic density membrane)|go:"GO:0099641"(anterograde axonal protein transport)|go:"GO:1902176"(negative regulation of oxidative stress-induced intrinsic apoptotic signaling pathway)|go:"GO:1903202"(negative regulation of oxidative stress-induced cell death)|go:"GO:1904115"(axon cytoplasm)|go:"GO:2001028"(positive regulation of endothelial cell chemotaxis)|go:"GO:2001234"(negative regulation of apoptotic signaling pathway)|interpro:IPR001436(Alpha crystallin/Heat shock protein)|interpro:IPR002068(Heat shock protein Hsp20)|interpro:IPR008978(HSP20-like chaperone)|interpro:IPR037876|mint:P14602|reactome:R-MMU-4420097|reactome:R-MMU-450408|reactome:R-MMU-5687128|reactome:R-MMU-9009391|refseq:NP_038588.2	-	chain-seq-start:60|chain-seq-end:166	-	figure legend:ST1.3|comment:acid-eluted fraction|dataset:Rare diseases - Interactions investigated in the context of Rare genetic disease|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2020/12/04	2020/12/21	rogid:mvYK6+YgIN/WuGLBCWqsqPLfDyQ10090	rogid:c79cDHl0WGQlEO7vGeDaZfr2oAE10090	rigid:2GOxg3PEbB4/d/naM3ax5e8q84s	false	mutation:34-34	-	-	-	psi-mi:"MI:0082"(peptide massfingerprinting)	psi-mi:"MI:0082"(peptide massfingerprinting)
uniprotkb:P97493-PRO_0000034151	uniprotkb:P16858	intact:EBI-26567598	intact:EBI-444871|uniprotkb:Q0QEU0|uniprotkb:Q3THM2|uniprotkb:Q3TUI2|uniprotkb:Q3UMT2|uniprotkb:Q4V783|uniprotkb:Q569X2|uniprotkb:Q569X5|uniprotkb:Q5U410|uniprotkb:A6H6A8|ensembl:ENSMUSP00000073289|ensembl:ENSMUSP00000113213	psi-mi:p97493-pro_0000034151(display_long)|uniprotkb:Thioredoxin-2(gene name synonym)|uniprotkb:Txn2(gene name)|psi-mi:Txn2(display_short)	psi-mi:g3p_mouse(display_long)|uniprotkb:Gapdh(gene name)|psi-mi:Gapdh(display_short)|uniprotkb:Gapd(gene name synonym)|uniprotkb:Peptidyl-cysteine S-nitrosylase GAPDH(gene name synonym)	psi-mi:"MI:0096"(pull down)	Chasapis et al. (2019)	pubmed:31018154|imex:IM-28571	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26500005|imex:IM-28571-43	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	intact:EBI-8354432(chain-parent)	refseq:NP_032110.1|refseq:XP_001476757.1|ensembl:ENSMUSG00000057666(gene)|ensembl:ENSMUST00000073605(transcript)|ensembl:ENSMUST00000118875(transcript)|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0001819"(positive regulation of cytokine production)|go:"GO:0004365"("glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity")|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005811"(lipid droplet)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005975"(carbohydrate metabolic process)|go:"GO:0006094"(gluconeogenesis)|go:"GO:0006096"(glycolytic process)|go:"GO:0006915"(apoptotic process)|go:"GO:0008017"(microtubule binding)|go:"GO:0010951"(negative regulation of endopeptidase activity)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0017148"(negative regulation of translation)|go:"GO:0019828"(aspartic-type endopeptidase inhibitor activity)|go:"GO:0019899"(enzyme binding)|go:"GO:0019933"(cAMP-mediated signaling)|go:"GO:0031640"(killing of cells of another organism)|go:"GO:0031906"(late endosome lumen)|go:"GO:0031965"(nuclear membrane)|go:"GO:0032481"(positive regulation of type I interferon production)|go:"GO:0035605"(peptidyl-cysteine S-nitrosylase activity)|go:"GO:0035606"(peptidyl-cysteine S-trans-nitrosylation)|go:"GO:0042802"(identical protein binding)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043209"(myelin sheath)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0050661"(NADP binding)|go:"GO:0050821"(protein stabilization)|go:"GO:0050832"(defense response to fungus)|go:"GO:0051287"(NAD binding)|go:"GO:0051402"(neuron apoptotic process)|go:"GO:0051873"(killing by host of symbiont cells)|go:"GO:0060359"(response to ammonium ion)|go:"GO:0061844"(antimicrobial humoral immune response mediated by antimicrobial peptide)|go:"GO:0071346"(cellular response to interferon-gamma)|go:"GO:0097452"(GAIT complex)|go:"GO:0097718"(disordered domain specific binding)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099092"(postsynaptic density, intracellular component)|go:"GO:1905460"(negative regulation of vascular associated smooth muscle cell apoptotic process)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR006424(Glyceraldehyde-3-phosphate dehydrogenase, type I)|interpro:IPR020828|interpro:IPR020829|interpro:IPR020830|interpro:IPR020831|interpro:IPR036291|mint:P16858|rcsb pdb:6LGJ|rcsb pdb:6LGK|rcsb pdb:6LGM|reactome:R-MMU-70171|reactome:R-MMU-70263|refseq:NP_001276655.1|dip:DIP-31404N	-	chain-seq-start:60|chain-seq-end:166	-	figure legend:ST1.3|comment:acid-eluted fraction|dataset:Rare diseases - Interactions investigated in the context of Rare genetic disease|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2020/12/04	2020/12/21	rogid:mvYK6+YgIN/WuGLBCWqsqPLfDyQ10090	rogid:SkcdXZ+143DDQFioo6mNWNpCLTI10090	rigid:2GOxg3PEbB4/d/naM3ax5e8q84s	false	mutation:34-34	-	-	-	psi-mi:"MI:0082"(peptide massfingerprinting)	psi-mi:"MI:0082"(peptide massfingerprinting)
uniprotkb:P97493-PRO_0000034151	uniprotkb:P68033	intact:EBI-26567598	intact:EBI-352284|uniprotkb:P04270|ensembl:ENSMUSP00000087736	psi-mi:p97493-pro_0000034151(display_long)|uniprotkb:Thioredoxin-2(gene name synonym)|uniprotkb:Txn2(gene name)|psi-mi:Txn2(display_short)	psi-mi:actc_mouse(display_long)|uniprotkb:Actc1(gene name)|psi-mi:Actc1(display_short)|uniprotkb:Actc(gene name synonym)|uniprotkb:Alpha-cardiac actin(gene name synonym)	psi-mi:"MI:0096"(pull down)	Chasapis et al. (2019)	pubmed:31018154|imex:IM-28571	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26500005|imex:IM-28571-43	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	intact:EBI-8354432(chain-parent)	refseq:NP_033738.1|ensembl:ENSMUSG00000068614(gene)|ensembl:ENSMUST00000090269(transcript)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005869"(dynactin complex)|go:"GO:0005884"(actin filament)|go:"GO:0007015"(actin filament organization)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0017022"(myosin binding)|go:"GO:0030017"(sarcomere)|go:"GO:0030027"(lamellipodium)|go:"GO:0030048"(actin filament-based movement)|go:"GO:0030175"(filopodium)|go:"GO:0030240"(skeletal muscle thin filament assembly)|go:"GO:0031032"(actomyosin structure organization)|go:"GO:0031674"(I band)|go:"GO:0033275"(actin-myosin filament sliding)|go:"GO:0042493"|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0044297"(cell body)|go:"GO:0045202"(synapse)|go:"GO:0045471"(response to ethanol)|go:"GO:0055003"(cardiac myofibril assembly)|go:"GO:0055008"(cardiac muscle tissue morphogenesis)|go:"GO:0060047"(heart contraction)|go:"GO:0060048"(cardiac muscle contraction)|go:"GO:0070252"(actin-mediated cell contraction)|go:"GO:0090131"(mesenchyme migration)|go:"GO:0098978"(glutamatergic synapse)|interpro:IPR004000(Actin/actin-like)|interpro:IPR004001(Actin, conserved site)|interpro:IPR020902|interpro:IPR043129|mint:P68033|reactome:R-MMU-390522|reactome:R-MMU-8980692|reactome:R-MMU-9013026	-	chain-seq-start:60|chain-seq-end:166	-	figure legend:ST1.3|comment:acid-eluted fraction|dataset:Rare diseases - Interactions investigated in the context of Rare genetic disease|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2020/12/04	2020/12/21	rogid:mvYK6+YgIN/WuGLBCWqsqPLfDyQ10090	rogid:U/lKYqWUWMSC3fBHFaAcgzfk+3w10090	rigid:2GOxg3PEbB4/d/naM3ax5e8q84s	false	mutation:34-34	-	-	-	psi-mi:"MI:0082"(peptide massfingerprinting)	psi-mi:"MI:0082"(peptide massfingerprinting)
uniprotkb:P97493-PRO_0000034151	uniprotkb:Q9D7X3	intact:EBI-26567598	intact:EBI-8320546|intact:MINT-4093702|ensembl:ENSMUSP00000003612|ensembl:ENSMUSP00000102790	psi-mi:p97493-pro_0000034151(display_long)|uniprotkb:Thioredoxin-2(gene name synonym)|uniprotkb:Txn2(gene name)|psi-mi:Txn2(display_short)	psi-mi:dus3_mouse(display_long)|uniprotkb:Dusp3(gene name)|psi-mi:Dusp3(display_short)|uniprotkb:T-DSP11(gene name synonym)|uniprotkb:Vaccinia H1-related phosphatase(gene name synonym)	psi-mi:"MI:0096"(pull down)	Chasapis et al. (2019)	pubmed:31018154|imex:IM-28571	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26500013|imex:IM-28571-23	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	intact:EBI-8354432(chain-parent)	refseq:NP_082483.1|ensembl:ENSMUSG00000003518(gene)|ensembl:ENSMUST00000003612(transcript)|ensembl:ENSMUST00000107172(transcript)|go:"GO:0000188"(obsolete inactivation of MAPK activity)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0001772"(immunological synapse)|go:"GO:0004721"(phosphoprotein phosphatase activity)|go:"GO:0004725"(protein tyrosine phosphatase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006470"(protein dephosphorylation)|go:"GO:0008092"(cytoskeletal protein binding)|go:"GO:0008138"(protein tyrosine/serine/threonine phosphatase activity)|go:"GO:0016311"(dephosphorylation)|go:"GO:0016791"(phosphatase activity)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030336"(negative regulation of cell migration)|go:"GO:0030971"(receptor tyrosine kinase binding)|go:"GO:0033549"(MAP kinase phosphatase activity)|go:"GO:0035335"(peptidyl-tyrosine dephosphorylation)|go:"GO:0042059"(negative regulation of epidermal growth factor receptor signaling pathway)|go:"GO:0043409"(negative regulation of MAPK cascade)|go:"GO:0045931"(positive regulation of mitotic cell cycle)|go:"GO:0046329"(negative regulation of JNK cascade)|go:"GO:0050860"(negative regulation of T cell receptor signaling pathway)|go:"GO:0050868"(negative regulation of T cell activation)|go:"GO:0050922"(negative regulation of chemotaxis)|go:"GO:0051893"(regulation of focal adhesion assembly)|go:"GO:0070373"(negative regulation of ERK1 and ERK2 cascade)|go:"GO:0071364"(cellular response to epidermal growth factor stimulus)|go:"GO:0106306"|go:"GO:0106307"|go:"GO:0120183"(positive regulation of focal adhesion disassembly)|go:"GO:1990782"(protein tyrosine kinase binding)|interpro:IPR000340(Protein-tyrosine phosphatase, dual specificity)|interpro:IPR000387(Protein-tyrosine phosphatase)|interpro:IPR016130(Protein-tyrosine phosphatase, active site)|interpro:IPR020405|interpro:IPR020422|interpro:IPR029021|mint:Q9D7X3|reactome:R-MMU-202670|go:"GO:1990264"(peptidyl-tyrosine dephosphorylation involved in inactivation of protein kinase activity)	-	chain-seq-start:60|chain-seq-end:166	comment:mint|function:This protein shows activity both toward tyrosine-protein phosphate as well as with serine-protein phosphate	figure legend:ST1.4 ST1.5 ST1.6|comment:DTT-eluted fraction|comment:The results in table 1.4,1.5 and 1.6 have been pooled together since they belong to the same experiment.|dataset:Rare diseases - Interactions investigated in the context of Rare genetic disease|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2020/12/04	2020/12/21	rogid:mvYK6+YgIN/WuGLBCWqsqPLfDyQ10090	rogid:CPkFDe9SCv4Nq8Dwl5NRteIKckg10090	rigid:U806iAk/nRbo20C3P3OsFasoYLY	false	mutation:34-34	-	-	-	psi-mi:"MI:0082"(peptide massfingerprinting)	psi-mi:"MI:0082"(peptide massfingerprinting)
uniprotkb:P97493-PRO_0000034151	uniprotkb:Q922B1	intact:EBI-26567598	intact:EBI-8347274|intact:MINT-1860392|ensembl:ENSMUSP00000039507	psi-mi:p97493-pro_0000034151(display_long)|uniprotkb:Thioredoxin-2(gene name synonym)|uniprotkb:Txn2(gene name)|psi-mi:Txn2(display_short)	psi-mi:macd1_mouse(display_long)|uniprotkb:Lrp16(gene name synonym)|uniprotkb:Macrod1(gene name)|psi-mi:Macrod1(display_short)|uniprotkb:Protein LRP16(gene name synonym)|uniprotkb:MACRO domain-containing protein 1(gene name synonym)|uniprotkb:O-acetyl-ADP-ribose deacetylase MACROD1(gene name synonym)|uniprotkb:[Protein ADP-ribosylaspartate] hydrolase MACROD1(gene name synonym)|uniprotkb:[Protein ADP-ribosylglutamate] hydrolase MACROD1(gene name synonym)	psi-mi:"MI:0096"(pull down)	Chasapis et al. (2019)	pubmed:31018154|imex:IM-28571	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26500013|imex:IM-28571-23	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	intact:EBI-8354432(chain-parent)	refseq:NP_598908.2|ensembl:ENSMUSG00000036278(gene)|ensembl:ENSMUST00000040261(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0016798"(hydrolase activity, acting on glycosyl bonds)|go:"GO:0019213"(deacetylase activity)|go:"GO:0042278"(purine nucleoside metabolic process)|go:"GO:0051725"(protein de-ADP-ribosylation)|go:"GO:0140291"(peptidyl-glutamate ADP-deribosylation)|go:"GO:0140293"(ADP-ribosylglutamate hydrolase activity)|interpro:IPR002589(Appr-1-p processing)|interpro:IPR043472|mint:Q922B1	-	chain-seq-start:60|chain-seq-end:166	comment:mint	figure legend:ST1.4 ST1.5 ST1.6|comment:DTT-eluted fraction|comment:The results in table 1.4,1.5 and 1.6 have been pooled together since they belong to the same experiment.|dataset:Rare diseases - Interactions investigated in the context of Rare genetic disease|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2020/12/04	2020/12/21	rogid:mvYK6+YgIN/WuGLBCWqsqPLfDyQ10090	rogid:bhne9D8soTRoeGPB7vapFutxL3Y10090	rigid:U806iAk/nRbo20C3P3OsFasoYLY	false	mutation:34-34	-	-	-	psi-mi:"MI:0082"(peptide massfingerprinting)	psi-mi:"MI:0082"(peptide massfingerprinting)
uniprotkb:P97493-PRO_0000034151	uniprotkb:Q8VBT1	intact:EBI-26567598	intact:EBI-8345141|intact:MINT-4136992|uniprotkb:Q3UVB8|uniprotkb:B2RU93|uniprotkb:Q8BUK2|ensembl:ENSMUSP00000044936	psi-mi:p97493-pro_0000034151(display_long)|uniprotkb:Thioredoxin-2(gene name synonym)|uniprotkb:Txn2(gene name)|psi-mi:Txn2(display_short)	psi-mi:txlnb_mouse(display_long)|uniprotkb:Txlnb(gene name)|psi-mi:Txlnb(display_short)|uniprotkb:Mdp77(gene name synonym)|uniprotkb:Muscle-derived protein 77(gene name synonym)	psi-mi:"MI:0096"(pull down)	Chasapis et al. (2019)	pubmed:31018154|imex:IM-28571	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26500013|imex:IM-28571-23	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	intact:EBI-8354432(chain-parent)	refseq:NP_619534.2|ensembl:ENSMUSG00000039891(gene)|ensembl:ENSMUST00000037964(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0019905"(syntaxin binding)|interpro:IPR026183|mint:Q8VBT1	-	chain-seq-start:60|chain-seq-end:166	comment:mint|function:Promotes motor nerve regeneration. May be involved in intracellular vesicle traffic	figure legend:ST1.4 ST1.5 ST1.6|comment:DTT-eluted fraction|comment:The results in table 1.4,1.5 and 1.6 have been pooled together since they belong to the same experiment.|dataset:Rare diseases - Interactions investigated in the context of Rare genetic disease|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2020/12/04	2020/12/21	rogid:mvYK6+YgIN/WuGLBCWqsqPLfDyQ10090	rogid:XJFhpi3mkSVyJwYZROmHwnvsof010090	rigid:U806iAk/nRbo20C3P3OsFasoYLY	false	mutation:34-34	-	-	-	psi-mi:"MI:0082"(peptide massfingerprinting)	psi-mi:"MI:0082"(peptide massfingerprinting)
uniprotkb:P97493-PRO_0000034151	uniprotkb:Q9JHR4	intact:EBI-26567598	intact:EBI-8341233|intact:MINT-4129688	psi-mi:p97493-pro_0000034151(display_long)|uniprotkb:Thioredoxin-2(gene name synonym)|uniprotkb:Txn2(gene name)|psi-mi:Txn2(display_short)	psi-mi:q9jhr4_mouse(display_long)|uniprotkb:Myh4(gene name)|psi-mi:Myh4(display_short)|uniprotkb:MYHC-IIB(gene name synonym)	psi-mi:"MI:0096"(pull down)	Chasapis et al. (2019)	pubmed:31018154|imex:IM-28571	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26500013|imex:IM-28571-23	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	intact:EBI-8354432(chain-parent)	mint:Q9JHR4|go:"GO:0016459"(myosin complex)|interpro:IPR002928(Myosin tail)|interpro:IPR014751(DNA double-strand break repair and VJ recombination XRCC4, C-terminal)	-	chain-seq-start:60|chain-seq-end:166	comment:"fragmentation type: fragment"|comment:mint	figure legend:ST1.4 ST1.5 ST1.6|comment:DTT-eluted fraction|comment:The results in table 1.4,1.5 and 1.6 have been pooled together since they belong to the same experiment.|dataset:Rare diseases - Interactions investigated in the context of Rare genetic disease|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2020/12/04	2020/12/21	rogid:mvYK6+YgIN/WuGLBCWqsqPLfDyQ10090	rogid:tl+nH18ol7idfWOpuWIP/Jb+09010090	rigid:U806iAk/nRbo20C3P3OsFasoYLY	false	mutation:34-34	-	-	-	psi-mi:"MI:0082"(peptide massfingerprinting)	psi-mi:"MI:0082"(peptide massfingerprinting)
uniprotkb:P97493-PRO_0000034151	uniprotkb:Q62234	intact:EBI-26567598	intact:EBI-8344887|intact:UNK-5482362|uniprotkb:Q6PAC0|intact:MINT-4102904|uniprotkb:Q546T8|ensembl:ENSMUSP00000072945	psi-mi:p97493-pro_0000034151(display_long)|uniprotkb:Thioredoxin-2(gene name synonym)|uniprotkb:Txn2(gene name)|psi-mi:Txn2(display_short)	psi-mi:myom1_mouse(display_long)|uniprotkb:Myom1(gene name)|psi-mi:Myom1(display_short)|uniprotkb:Myomesin family member 1(gene name synonym)|uniprotkb:Skelemin(gene name synonym)	psi-mi:"MI:0096"(pull down)	Chasapis et al. (2019)	pubmed:31018154|imex:IM-28571	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26500013|imex:IM-28571-23	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	intact:EBI-8354432(chain-parent)	refseq:NP_034997.2|refseq:NP_001077403.1|ensembl:ENSMUSG00000024049(gene)|ensembl:ENSMUST00000073211(transcript)|go:"GO:0002074"(extraocular skeletal muscle development)|go:"GO:0005200"(structural constituent of cytoskeleton)|go:"GO:0005856"(cytoskeleton)|go:"GO:0006936"(muscle contraction)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010737"(protein kinase A signaling)|go:"GO:0019900"(kinase binding)|go:"GO:0030017"(sarcomere)|go:"GO:0031430"(M band)|go:"GO:0032982"(myosin filament)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0050714"(positive regulation of protein secretion)|go:"GO:0051015"(actin filament binding)|interpro:IPR003598(Immunoglobulin subtype 2)|interpro:IPR003599(Immunoglobulin subtype)|interpro:IPR003961(Fibronectin, type III)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR013098(Immunoglobulin I-set)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR036116|interpro:IPR036179|mint:Q62234|rcsb pdb:2JTD|rcsb pdb:4V10	-	chain-seq-start:60|chain-seq-end:166	comment:mint|function:May link the intermediate filament cytoskeleton to the M-disc of the myofibrils in striated muscle. May also contact myosin filaments. Also binds beta-integrins	figure legend:ST1.4 ST1.5 ST1.6|comment:DTT-eluted fraction|comment:The results in table 1.4,1.5 and 1.6 have been pooled together since they belong to the same experiment.|dataset:Rare diseases - Interactions investigated in the context of Rare genetic disease|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2020/12/04	2020/12/21	rogid:mvYK6+YgIN/WuGLBCWqsqPLfDyQ10090	rogid:sfJeAhoFhpjW9v1ci8pVYx2k30410090	rigid:U806iAk/nRbo20C3P3OsFasoYLY	false	mutation:34-34	-	-	-	psi-mi:"MI:0082"(peptide massfingerprinting)	psi-mi:"MI:0082"(peptide massfingerprinting)
uniprotkb:P97493-PRO_0000034151	uniprotkb:P05977	intact:EBI-26567598	intact:EBI-8344549|intact:MINT-149848|uniprotkb:P05978|ensembl:ENSMUSP00000027151	psi-mi:p97493-pro_0000034151(display_long)|uniprotkb:Thioredoxin-2(gene name synonym)|uniprotkb:Txn2(gene name)|psi-mi:Txn2(display_short)	psi-mi:myl1_mouse(display_long)|uniprotkb:Myl1(gene name)|psi-mi:Myl1(display_short)|uniprotkb:Mylf(gene name synonym)|uniprotkb:Myosin light chain alkali 1/2(gene name synonym)	psi-mi:"MI:0096"(pull down)	Chasapis et al. (2019)	pubmed:31018154|imex:IM-28571	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26500013|imex:IM-28571-23	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	intact:EBI-8354432(chain-parent)	refseq:NP_001106858.1|refseq:NP_067260.1|refseq:XP_006495826.1|ensembl:ENSMUSG00000061816(gene)|ensembl:ENSMUST00000027151(transcript)|go:"GO:0005509"(calcium ion binding)|go:"GO:0006936"(muscle contraction)|go:"GO:0008307"(structural constituent of muscle)|go:"GO:0016459"(myosin complex)|go:"GO:0030016"(myofibril)|go:"GO:0043292"(contractile fiber)|go:"GO:0060048"(cardiac muscle contraction)|interpro:IPR002048(Calcium-binding EF-hand)|interpro:IPR011992(EF-Hand type)|mint:P05977|rcsb pdb:7NEP|reactome:R-MMU-390522	-	chain-seq-start:60|chain-seq-end:166	function:Regulatory light chain of myosin. Does not bind calcium|comment:mint	figure legend:ST1.4 ST1.5 ST1.6|comment:DTT-eluted fraction|comment:The results in table 1.4,1.5 and 1.6 have been pooled together since they belong to the same experiment.|dataset:Rare diseases - Interactions investigated in the context of Rare genetic disease|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2020/12/04	2020/12/21	rogid:mvYK6+YgIN/WuGLBCWqsqPLfDyQ10090	rogid:FfCBulCjMkfLCUt59AT7go5hI9s10090	rigid:U806iAk/nRbo20C3P3OsFasoYLY	false	mutation:34-34	-	-	-	psi-mi:"MI:0082"(peptide massfingerprinting)	psi-mi:"MI:0082"(peptide massfingerprinting)
uniprotkb:P97493-PRO_0000034151	uniprotkb:P02088	intact:EBI-26567598	intact:EBI-494201|uniprotkb:Q54AI0|uniprotkb:Q91V86|uniprotkb:Q9CRZ2|uniprotkb:Q9CXH5|uniprotkb:Q9CY12|uniprotkb:Q9CY54|uniprotkb:Q9R0S6	psi-mi:p97493-pro_0000034151(display_long)|uniprotkb:Thioredoxin-2(gene name synonym)|uniprotkb:Txn2(gene name)|psi-mi:Txn2(display_short)	psi-mi:hbb1_mouse(display_long)|uniprotkb:Hemoglobin beta-1 chain(gene name synonym)|uniprotkb:Beta-1-globin(gene name synonym)|uniprotkb:Hemoglobin beta-major chain(gene name synonym)|uniprotkb:Hbb-b1(gene name)|psi-mi:Hbb-b1(display_short)	psi-mi:"MI:0096"(pull down)	Chasapis et al. (2019)	pubmed:31018154|imex:IM-28571	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26500013|imex:IM-28571-23	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	intact:EBI-8354432(chain-parent)	refseq:NP_001188320.1|refseq:NP_032246.2|interpro:IPR009050(Globin-like)|interpro:IPR000971(Globin, subset)|interpro:IPR002337(Haemoglobin, beta)|interpro:IPR012292(Globin)|refseq:NP_001265090.1|go:"GO:0005344"(oxygen carrier activity)|go:"GO:0005833"(hemoglobin complex)|go:"GO:0010999"(regulation of eIF2 alpha phosphorylation by heme)|go:"GO:0015671"(oxygen transport)|go:"GO:0019825"(oxygen binding)|go:"GO:0020037"(heme binding)|go:"GO:0030097"(hemopoiesis)|go:"GO:0031721"(hemoglobin alpha binding)|go:"GO:0031838"(haptoglobin-hemoglobin complex)|go:"GO:0042744"(hydrogen peroxide catabolic process)|go:"GO:0043177"(organic acid binding)|go:"GO:0043209"(myelin sheath)|go:"GO:0046872"(metal ion binding)|go:"GO:0048821"(erythrocyte development)|go:"GO:0098869"(cellular oxidant detoxification)|rcsb pdb:1JEB|rcsb pdb:3HRW|mint:P02088	-	chain-seq-start:60|chain-seq-end:166	-	figure legend:ST1.4 ST1.5 ST1.6|comment:DTT-eluted fraction|comment:The results in table 1.4,1.5 and 1.6 have been pooled together since they belong to the same experiment.|dataset:Rare diseases - Interactions investigated in the context of Rare genetic disease|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2020/12/04	2020/12/21	rogid:mvYK6+YgIN/WuGLBCWqsqPLfDyQ10090	rogid:/W1Bo3qzhsm3Fzb/joImMwzE/Dg10090	rigid:U806iAk/nRbo20C3P3OsFasoYLY	false	mutation:34-34	-	-	-	psi-mi:"MI:0082"(peptide massfingerprinting)	psi-mi:"MI:0082"(peptide massfingerprinting)
uniprotkb:P97493-PRO_0000034151	uniprotkb:P13707	intact:EBI-26567598	intact:EBI-1634419|uniprotkb:Q3UVM3|uniprotkb:Q5DTS5|ensembl:ENSMUSP00000023760	psi-mi:p97493-pro_0000034151(display_long)|uniprotkb:Thioredoxin-2(gene name synonym)|uniprotkb:Txn2(gene name)|psi-mi:Txn2(display_short)	psi-mi:gpda_mouse(display_long)|uniprotkb:Gpd1(gene name)|psi-mi:Gpd1(display_short)|uniprotkb:Gdc-1(gene name synonym)|uniprotkb:Gdc1(gene name synonym)|uniprotkb:Kiaa4010(gene name synonym)	psi-mi:"MI:0096"(pull down)	Chasapis et al. (2019)	pubmed:31018154|imex:IM-28571	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26500013|imex:IM-28571-23	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	intact:EBI-8354432(chain-parent)	refseq:NP_034401.1|ensembl:ENSMUSG00000023019(gene)|ensembl:ENSMUST00000023760(transcript)|go:"GO:0004367"(glycerol-3-phosphate dehydrogenase [NAD+] activity)|go:"GO:0004368"("glycerol-3-phosphate dehydrogenase (quinone) activity")|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0005975"(carbohydrate metabolic process)|go:"GO:0006072"(glycerol-3-phosphate metabolic process)|go:"GO:0006094"(gluconeogenesis)|go:"GO:0006116"(NADH oxidation)|go:"GO:0006127"(glycerophosphate shuttle)|go:"GO:0006734"(NADH metabolic process)|go:"GO:0009331"(glycerol-3-phosphate dehydrogenase complex)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0045821"(positive regulation of glycolytic process)|go:"GO:0046168"(glycerol-3-phosphate catabolic process)|go:"GO:0046486"(glycerolipid metabolic process)|go:"GO:0051287"(NAD binding)|go:"GO:0071320"(cellular response to cAMP)|go:"GO:0071356"(cellular response to tumor necrosis factor)|interpro:IPR006109(NAD-dependent glycerol-3-phosphate dehydrogenase, C-terminal)|interpro:IPR006168(NAD-dependent glycerol-3-phosphate dehydrogenase)|interpro:IPR008927(6-phosphogluconate dehydrogenase, C-terminal-like)|interpro:IPR011128(NAD-dependent glycerol-3-phosphate dehydrogenase, N-terminal)|interpro:IPR013328(Dehydrogenase, multihelical)|interpro:IPR017751(NAD-dependent glycerol-3-phosphate dehydrogenase, eukaryotic)|interpro:IPR036291|mint:P13707|reactome:R-MMU-1483166	-	chain-seq-start:60|chain-seq-end:166	-	figure legend:ST1.4 ST1.5 ST1.6|comment:DTT-eluted fraction|comment:The results in table 1.4,1.5 and 1.6 have been pooled together since they belong to the same experiment.|dataset:Rare diseases - Interactions investigated in the context of Rare genetic disease|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2020/12/04	2020/12/21	rogid:mvYK6+YgIN/WuGLBCWqsqPLfDyQ10090	rogid:qAqO6vxFpOQeXUPIpNI5A2fDBN410090	rigid:U806iAk/nRbo20C3P3OsFasoYLY	false	mutation:34-34	-	-	-	psi-mi:"MI:0082"(peptide massfingerprinting)	psi-mi:"MI:0082"(peptide massfingerprinting)
uniprotkb:P97493-PRO_0000034151	uniprotkb:P53996	intact:EBI-26567598	intact:EBI-2552945|ensembl:ENSMUSP00000032138|uniprotkb:Q80Y06|uniprotkb:Q8BP23	psi-mi:p97493-pro_0000034151(display_long)|uniprotkb:Thioredoxin-2(gene name synonym)|uniprotkb:Txn2(gene name)|psi-mi:Txn2(display_short)	psi-mi:cnbp_mouse(display_long)|uniprotkb:Cnbp(gene name)|psi-mi:Cnbp(display_short)|uniprotkb:Cnbp1(gene name synonym)|uniprotkb:Znf9(gene name synonym)|uniprotkb:Zinc finger protein 9(gene name synonym)|uniprotkb:Cellular nucleic acid-binding protein(gene name synonym)	psi-mi:"MI:0096"(pull down)	Chasapis et al. (2019)	pubmed:31018154|imex:IM-28571	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26500013|imex:IM-28571-23	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	intact:EBI-8354432(chain-parent)	refseq:NP_001103215.1|refseq:NP_038521.1|ensembl:ENSMUSG00000030057(gene)|ensembl:ENSMUST00000032138(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0003727"(single-stranded RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005829"(cytosol)|go:"GO:0008270"(zinc ion binding)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0045182"(translation regulator activity)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0051880"(G-quadruplex DNA binding)|go:"GO:0071919"(G-quadruplex DNA formation)|go:"GO:2000767"(positive regulation of cytoplasmic translation)|interpro:IPR001878(Zinc finger, CCHC-type)|interpro:IPR036875|mint:P53996|refseq:NP_001334254.1	-	chain-seq-start:60|chain-seq-end:166	-	figure legend:ST1.4 ST1.5 ST1.6|comment:DTT-eluted fraction|comment:The results in table 1.4,1.5 and 1.6 have been pooled together since they belong to the same experiment.|dataset:Rare diseases - Interactions investigated in the context of Rare genetic disease|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2020/12/04	2020/12/21	rogid:mvYK6+YgIN/WuGLBCWqsqPLfDyQ10090	rogid:qXoAcOW8P42Ch0udEU00YlhTgn810090	rigid:U806iAk/nRbo20C3P3OsFasoYLY	false	mutation:34-34	-	-	-	psi-mi:"MI:0082"(peptide massfingerprinting)	psi-mi:"MI:0082"(peptide massfingerprinting)
uniprotkb:P97493-PRO_0000034151	uniprotkb:Q8R112	intact:EBI-26567598	intact:EBI-13948648	psi-mi:p97493-pro_0000034151(display_long)|uniprotkb:Thioredoxin-2(gene name synonym)|uniprotkb:Txn2(gene name)|psi-mi:Txn2(display_short)	psi-mi:q8r112_mouse(display_long)|uniprotkb:Ttn(gene name)|psi-mi:Ttn(display_short)	psi-mi:"MI:0096"(pull down)	Chasapis et al. (2019)	pubmed:31018154|imex:IM-28571	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26500013|imex:IM-28571-23	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	intact:EBI-8354432(chain-parent)	mint:Q8R112|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR013098(Immunoglobulin I-set)|interpro:IPR003599(Immunoglobulin subtype)|interpro:IPR003598(Immunoglobulin subtype 2)|interpro:IPR036179	-	chain-seq-start:60|chain-seq-end:166	-	figure legend:ST1.4 ST1.5 ST1.6|comment:DTT-eluted fraction|comment:The results in table 1.4,1.5 and 1.6 have been pooled together since they belong to the same experiment.|dataset:Rare diseases - Interactions investigated in the context of Rare genetic disease|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2020/12/04	2020/12/21	rogid:mvYK6+YgIN/WuGLBCWqsqPLfDyQ10090	rogid:NAY7L7ualjBgtM4uQWL0UChqTKM10090	rigid:U806iAk/nRbo20C3P3OsFasoYLY	false	mutation:34-34	-	-	-	psi-mi:"MI:0082"(peptide massfingerprinting)	psi-mi:"MI:0082"(peptide massfingerprinting)
uniprotkb:P97493-PRO_0000034151	uniprotkb:P20801	intact:EBI-26567598	intact:EBI-26500359|ensembl:ENSMUSP00000099384	psi-mi:p97493-pro_0000034151(display_long)|uniprotkb:Thioredoxin-2(gene name synonym)|uniprotkb:Txn2(gene name)|psi-mi:Txn2(display_short)	psi-mi:tnnc2_mouse(display_long)|uniprotkb:Tnnc2(gene name)|psi-mi:Tnnc2(display_short)|uniprotkb:Tncs(gene name synonym)|uniprotkb:STNC(gene name synonym)	psi-mi:"MI:0096"(pull down)	Chasapis et al. (2019)	pubmed:31018154|imex:IM-28571	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26500013|imex:IM-28571-23	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	intact:EBI-8354432(chain-parent)	ensembl:ENSMUSG00000017300(gene)|ensembl:ENSMUST00000103095(transcript)|go:"GO:0003009"(skeletal muscle contraction)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005861"(troponin complex)|go:"GO:0006937"(regulation of muscle contraction)|go:"GO:0048306"(calcium-dependent protein binding)|go:"GO:0051015"(actin filament binding)|interpro:IPR002048(Calcium-binding EF-hand)|interpro:IPR011992(EF-Hand type)|interpro:IPR018247|mint:P20801|reactome:R-MMU-390522|refseq:NP_033420.1	-	chain-seq-start:60|chain-seq-end:166	-	figure legend:ST1.4 ST1.5 ST1.6|comment:DTT-eluted fraction|comment:The results in table 1.4,1.5 and 1.6 have been pooled together since they belong to the same experiment.|dataset:Rare diseases - Interactions investigated in the context of Rare genetic disease|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2020/12/04	2020/12/21	rogid:mvYK6+YgIN/WuGLBCWqsqPLfDyQ10090	rogid:g2aTW2nFdVOaWprQzl4y1j+V1Vs10090	rigid:U806iAk/nRbo20C3P3OsFasoYLY	false	mutation:34-34	-	-	-	psi-mi:"MI:0082"(peptide massfingerprinting)	psi-mi:"MI:0082"(peptide massfingerprinting)
uniprotkb:P97493-PRO_0000034151	uniprotkb:P17751	intact:EBI-26567598	intact:EBI-444877|uniprotkb:Q3TJH2|uniprotkb:Q3UC04|uniprotkb:Q3UKG9|uniprotkb:Q64513|uniprotkb:Q9CVF9|uniprotkb:Q9CWE7|ensembl:ENSMUSP00000130858	psi-mi:p97493-pro_0000034151(display_long)|uniprotkb:Thioredoxin-2(gene name synonym)|uniprotkb:Txn2(gene name)|psi-mi:Txn2(display_short)	psi-mi:tpis_mouse(display_long)|uniprotkb:Triose-phosphate isomerase(gene name synonym)|uniprotkb:Tpi1(gene name)|psi-mi:Tpi1(display_short)|uniprotkb:Tpi(gene name synonym)|uniprotkb:Methylglyoxal synthase(gene name synonym)	psi-mi:"MI:0096"(pull down)	Chasapis et al. (2019)	pubmed:31018154|imex:IM-28571	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26500013|imex:IM-28571-23	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	intact:EBI-8354432(chain-parent)	refseq:NP_033441.2|ensembl:ENSMUSG00000023456(gene)|ensembl:ENSMUST00000172132(transcript)|go:"GO:0004807"(triose-phosphate isomerase activity)|go:"GO:0005829"(cytosol)|go:"GO:0006006"(glucose metabolic process)|go:"GO:0006094"(gluconeogenesis)|go:"GO:0006096"(glycolytic process)|go:"GO:0008929"(methylglyoxal synthase activity)|go:"GO:0016853"(isomerase activity)|go:"GO:0019242"(methylglyoxal biosynthetic process)|go:"GO:0019563"(glycerol catabolic process)|go:"GO:0019682"(glyceraldehyde-3-phosphate metabolic process)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0046166"(glyceraldehyde-3-phosphate biosynthetic process)|interpro:IPR000652(Triosephosphate isomerase)|interpro:IPR013785(Aldolase-type TIM barrel)|interpro:IPR020861|interpro:IPR022896|interpro:IPR035990|mint:P17751|reactome:R-MMU-70171|reactome:R-MMU-70263	-	chain-seq-start:60|chain-seq-end:166	-	figure legend:ST1.4 ST1.5 ST1.6|comment:DTT-eluted fraction|comment:The results in table 1.4,1.5 and 1.6 have been pooled together since they belong to the same experiment.|dataset:Rare diseases - Interactions investigated in the context of Rare genetic disease|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2020/12/04	2020/12/21	rogid:mvYK6+YgIN/WuGLBCWqsqPLfDyQ10090	rogid:1+uasFpsjnuX50Ti23iaIawdp7k10090	rigid:U806iAk/nRbo20C3P3OsFasoYLY	false	mutation:34-34	-	-	-	psi-mi:"MI:0082"(peptide massfingerprinting)	psi-mi:"MI:0082"(peptide massfingerprinting)
uniprotkb:P97493-PRO_0000034151	uniprotkb:Q9DBC7	intact:EBI-26567598	intact:EBI-645677|uniprotkb:Q3UKU7|uniprotkb:Q9JHR5|uniprotkb:Q9JHR6|ensembl:ENSMUSP00000056500|ensembl:ENSMUSP00000102288	psi-mi:p97493-pro_0000034151(display_long)|uniprotkb:Thioredoxin-2(gene name synonym)|uniprotkb:Txn2(gene name)|psi-mi:Txn2(display_short)	psi-mi:kap0_mouse(display_long)|uniprotkb:Prkar1a(gene name)|psi-mi:Prkar1a(display_short)	psi-mi:"MI:0096"(pull down)	Chasapis et al. (2019)	pubmed:31018154|imex:IM-28571	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26500013|imex:IM-28571-23	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	intact:EBI-8354432(chain-parent)	refseq:NP_001300902.1|refseq:NP_001300903.1|refseq:NP_001300904.1|refseq:NP_001300905.1|refseq:NP_068680.1|refseq:XP_017169829.1|dip:DIP-32450N|ensembl:ENSMUSG00000020612(gene)|ensembl:ENSMUST00000049527(transcript)|ensembl:ENSMUST00000106677(transcript)|go:"GO:0001707"(mesoderm formation)|go:"GO:0001772"(immunological synapse)|go:"GO:0004862"(cAMP-dependent protein kinase inhibitor activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005771"(multivesicular body)|go:"GO:0005813"(centrosome)|go:"GO:0005930"(axoneme)|go:"GO:0005952"(cAMP-dependent protein kinase complex)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0006469"(negative regulation of protein kinase activity)|go:"GO:0007143"(female meiotic nuclear division)|go:"GO:0007507"(heart development)|go:"GO:0008283"(cell population proliferation)|go:"GO:0008603"(cAMP-dependent protein kinase regulator activity)|go:"GO:0009887"(animal organ morphogenesis)|go:"GO:0010738"(regulation of protein kinase A signaling)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030552"(cAMP binding)|go:"GO:0031588"(nucleotide-activated protein kinase complex)|go:"GO:0031594"(neuromuscular junction)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034236"(protein kinase A catalytic subunit binding)|reactome:R-MMU-983231|reactome:R-MMU-5610787|go:"GO:0044853"(plasma membrane raft)|go:"GO:0045202"(synapse)|go:"GO:0045214"(sarcomere organization)|go:"GO:0045835"(negative regulation of meiotic nuclear division)|go:"GO:0045859"(regulation of protein kinase activity)|go:"GO:0046007"(negative regulation of activated T cell proliferation)|go:"GO:0060038"(cardiac muscle cell proliferation)|go:"GO:0097224"(sperm connecting piece)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:2000480"(negative regulation of cAMP-dependent protein kinase activity)|interpro:IPR000595(Cyclic nucleotide-binding)|interpro:IPR003117(cAMP-dependent protein kinase, regulatory subunit, type I/II alpha/beta)|interpro:IPR014710(RmlC-like jelly roll fold)|interpro:IPR018488|interpro:IPR018490|mint:Q9DBC7|reactome:R-MMU-163615|reactome:R-MMU-164378|reactome:R-MMU-180024|reactome:R-MMU-432040|go:"GO:0043949"(regulation of cAMP-mediated signaling)|reactome:R-MMU-442720	-	chain-seq-start:60|chain-seq-end:166	-	figure legend:ST1.4 ST1.5 ST1.6|comment:DTT-eluted fraction|comment:The results in table 1.4,1.5 and 1.6 have been pooled together since they belong to the same experiment.|dataset:Rare diseases - Interactions investigated in the context of Rare genetic disease|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2020/12/04	2020/12/21	rogid:mvYK6+YgIN/WuGLBCWqsqPLfDyQ10090	rogid:0KqlQxZjK8QfS6VPEiTDtvHNTj410090	rigid:U806iAk/nRbo20C3P3OsFasoYLY	false	mutation:34-34	-	-	-	psi-mi:"MI:0082"(peptide massfingerprinting)	psi-mi:"MI:0082"(peptide massfingerprinting)
uniprotkb:P97493-PRO_0000034151	uniprotkb:P21550	intact:EBI-26567598	intact:EBI-1634301|ensembl:ENSMUSP00000072620|ensembl:ENSMUSP00000104188|ensembl:ENSMUSP00000128714	psi-mi:p97493-pro_0000034151(display_long)|uniprotkb:Thioredoxin-2(gene name synonym)|uniprotkb:Txn2(gene name)|psi-mi:Txn2(display_short)	psi-mi:enob_mouse(display_long)|uniprotkb:Eno3(gene name)|psi-mi:Eno3(display_short)|uniprotkb:Eno-3(gene name synonym)|uniprotkb:2-phospho-D-glycerate hydro-lyase(gene name synonym)|uniprotkb:Muscle-specific enolase(gene name synonym)|uniprotkb:Skeletal muscle enolase(gene name synonym)|uniprotkb:Enolase 3(gene name synonym)	psi-mi:"MI:0096"(pull down)	Chasapis et al. (2019)	pubmed:31018154|imex:IM-28571	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26500013|imex:IM-28571-23	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	intact:EBI-8354432(chain-parent)	refseq:NP_001129534.1|refseq:NP_031959.1|refseq:NP_001263214.1|refseq:XP_006532225.1|ensembl:ENSMUSG00000060600(gene)|ensembl:ENSMUST00000072841(transcript)|ensembl:ENSMUST00000108548(transcript)|ensembl:ENSMUST00000170716(transcript)|go:"GO:0000015"(phosphopyruvate hydratase complex)|go:"GO:0000287"(magnesium ion binding)|go:"GO:0004634"(phosphopyruvate hydratase activity)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006096"(glycolytic process)|go:"GO:0007568"(aging)|go:"GO:0016020"(membrane)|go:"GO:0032889"(regulation of vacuole fusion, non-autophagic)|go:"GO:0042493"|go:"GO:0042802"(identical protein binding)|go:"GO:0043403"(skeletal muscle tissue regeneration)|go:"GO:0044877"(protein-containing complex binding)|interpro:IPR000941(Enolase)|interpro:IPR020809|interpro:IPR020810|interpro:IPR020811|interpro:IPR029017|interpro:IPR036849|mint:P21550|reactome:R-MMU-70171|reactome:R-MMU-70263	-	chain-seq-start:60|chain-seq-end:166	-	figure legend:ST1.4 ST1.5 ST1.6|comment:DTT-eluted fraction|comment:The results in table 1.4,1.5 and 1.6 have been pooled together since they belong to the same experiment.|dataset:Rare diseases - Interactions investigated in the context of Rare genetic disease|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2020/12/04	2020/12/21	rogid:mvYK6+YgIN/WuGLBCWqsqPLfDyQ10090	rogid:CN/5EMhCFqpjAxZ04UHwcLN+eRI10090	rigid:U806iAk/nRbo20C3P3OsFasoYLY	false	mutation:34-34	-	-	-	psi-mi:"MI:0082"(peptide massfingerprinting)	psi-mi:"MI:0082"(peptide massfingerprinting)
uniprotkb:P97493-PRO_0000034151	uniprotkb:P56480	intact:EBI-26567598	intact:EBI-299482|ensembl:ENSMUSP00000026459|uniprotkb:Q0QEP4|uniprotkb:Q3TFD7|uniprotkb:Q3TIP9|uniprotkb:Q3TK44|uniprotkb:Q3TWD5|uniprotkb:Q3TX28|uniprotkb:Q3U6U4|uniprotkb:Q3U774|uniprotkb:Q3UB69|uniprotkb:Q3UF69|uniprotkb:Q8CI65|uniprotkb:Q8VEJ5|uniprotkb:Q9CTI7|uniprotkb:Q9CWX7	psi-mi:p97493-pro_0000034151(display_long)|uniprotkb:Thioredoxin-2(gene name synonym)|uniprotkb:Txn2(gene name)|psi-mi:Txn2(display_short)	psi-mi:atpb_mouse(display_long)|uniprotkb:Atp5f1b(gene name)|psi-mi:Atp5f1b(display_short)|uniprotkb:ATP synthase F1 subunit beta(gene name synonym)|uniprotkb:Atp5b(gene name synonym)	psi-mi:"MI:0096"(pull down)	Chasapis et al. (2019)	pubmed:31018154|imex:IM-28571	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26500013|imex:IM-28571-23	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	intact:EBI-8354432(chain-parent)	interpro:IPR024034|interpro:IPR027417|interpro:IPR036121|mint:P56480|reactome:R-MMU-1268020|reactome:R-MMU-163210|reactome:R-MMU-8949613|interpro:IPR020003|ensembl:ENSMUSG00000025393(gene)|ensembl:ENSMUST00000026459(transcript)|go:"GO:0000275"("mitochondrial proton-transporting ATP synthase complex, catalytic sector F(1)")|go:"GO:0001525"(angiogenesis)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005753"(mitochondrial proton-transporting ATP synthase complex)|go:"GO:0005886"(plasma membrane)|go:"GO:0006629"(lipid metabolic process)|go:"GO:0006754"(ATP biosynthetic process)|go:"GO:0006898"(receptor-mediated endocytosis)|go:"GO:0006933"(negative regulation of cell adhesion involved in substrate-bound cell migration)|go:"GO:0009986"(cell surface)|go:"GO:0016020"(membrane)|go:"GO:0030228"(lipoprotein particle receptor activity)|go:"GO:0031966"(mitochondrial membrane)|go:"GO:0042288"(MHC class I protein binding)|go:"GO:0042645"(mitochondrial nucleoid)|go:"GO:0042776"(mitochondrial ATP synthesis coupled proton transport)|go:"GO:0043209"(myelin sheath)|go:"GO:0043531"(ADP binding)|go:"GO:0043532"(angiostatin binding)|go:"GO:0043536"(positive regulation of blood vessel endothelial cell migration)|go:"GO:0045121"(membrane raft)|go:"GO:0045259"(proton-transporting ATP synthase complex)|go:"GO:0045261"("proton-transporting ATP synthase complex, catalytic core F(1)")|go:"GO:0046034"(ATP metabolic process)|go:"GO:0046933"(proton-transporting ATP synthase activity, rotational mechanism)|go:"GO:0046961"(proton-transporting ATPase activity, rotational mechanism)|go:"GO:0051453"(regulation of intracellular pH)|go:"GO:0098761"(cellular response to interleukin-7)|go:"GO:1902600"(proton transmembrane transport)|interpro:IPR000194(ATPase, F1/V1/A1 complex, alpha/beta subunit, nucleotide-binding)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR004100(ATPase, F1/V1/A1 complex, alpha/beta subunit, N-terminal)|interpro:IPR005722(ATPase, F1 complex, beta subunit)|go:"GO:0005524"(ATP binding)|refseq:NP_058054.2	-	chain-seq-start:60|chain-seq-end:166	-	figure legend:ST1.4 ST1.5 ST1.6|comment:DTT-eluted fraction|comment:The results in table 1.4,1.5 and 1.6 have been pooled together since they belong to the same experiment.|dataset:Rare diseases - Interactions investigated in the context of Rare genetic disease|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2020/12/04	2020/12/21	rogid:mvYK6+YgIN/WuGLBCWqsqPLfDyQ10090	rogid:ihjn7GQ1ZSBfGcfwEAYSiCIuq+410090	rigid:U806iAk/nRbo20C3P3OsFasoYLY	false	mutation:34-34	-	-	-	psi-mi:"MI:0082"(peptide massfingerprinting)	psi-mi:"MI:0082"(peptide massfingerprinting)
uniprotkb:P97493-PRO_0000034151	uniprotkb:P62737	intact:EBI-26567598	intact:EBI-5297932|uniprotkb:P03996|uniprotkb:P04108|ensembl:ENSMUSP00000048218	psi-mi:p97493-pro_0000034151(display_long)|uniprotkb:Thioredoxin-2(gene name synonym)|uniprotkb:Txn2(gene name)|psi-mi:Txn2(display_short)	psi-mi:acta_mouse(display_long)|uniprotkb:Acta2(gene name)|psi-mi:Acta2(display_short)|uniprotkb:Actsa(gene name synonym)|uniprotkb:Actvs(gene name synonym)|uniprotkb:Alpha-actin-2(gene name synonym)	psi-mi:"MI:0096"(pull down)	Chasapis et al. (2019)	pubmed:31018154|imex:IM-28571	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26500013|imex:IM-28571-23	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	intact:EBI-8354432(chain-parent)	refseq:NP_031418.1|ensembl:ENSMUSG00000035783(gene)|ensembl:ENSMUST00000039631(transcript)|go:"GO:0001725"(stress fiber)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005869"(dynactin complex)|go:"GO:0006936"(muscle contraction)|go:"GO:0008217"(regulation of blood pressure)|go:"GO:0009615"(response to virus)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0014829"(vascular associated smooth muscle contraction)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030027"(lamellipodium)|go:"GO:0030175"(filopodium)|go:"GO:0030485"(smooth muscle contractile fiber)|go:"GO:0044297"(cell body)|go:"GO:0061041"(regulation of wound healing)|go:"GO:0061870"(positive regulation of hepatic stellate cell migration)|go:"GO:0061874"(positive regulation of hepatic stellate cell contraction)|go:"GO:0070374"(positive regulation of ERK1 and ERK2 cascade)|go:"GO:0072144"(glomerular mesangial cell development)|go:"GO:0090131"(mesenchyme migration)|go:"GO:2000491"(positive regulation of hepatic stellate cell activation)|interpro:IPR004000(Actin/actin-like)|interpro:IPR004001(Actin, conserved site)|interpro:IPR020902|interpro:IPR043129|mint:P62737|reactome:R-MMU-445355	-	chain-seq-start:60|chain-seq-end:166	-	figure legend:ST1.4 ST1.5 ST1.6|comment:DTT-eluted fraction|comment:The results in table 1.4,1.5 and 1.6 have been pooled together since they belong to the same experiment.|dataset:Rare diseases - Interactions investigated in the context of Rare genetic disease|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2020/12/04	2020/12/21	rogid:mvYK6+YgIN/WuGLBCWqsqPLfDyQ10090	rogid:mRZGUdL/jBuj6nVHtxoasZuA7yA10090	rigid:U806iAk/nRbo20C3P3OsFasoYLY	false	mutation:34-34	-	-	-	psi-mi:"MI:0082"(peptide massfingerprinting)	psi-mi:"MI:0082"(peptide massfingerprinting)
uniprotkb:P97493-PRO_0000034151	uniprotkb:Q99KI0	intact:EBI-26567598	intact:EBI-444886|uniprotkb:Q3UDK9|uniprotkb:Q3ULG9|uniprotkb:Q3UNH7|uniprotkb:Q505P4|ensembl:ENSMUSP00000023116	psi-mi:p97493-pro_0000034151(display_long)|uniprotkb:Thioredoxin-2(gene name synonym)|uniprotkb:Txn2(gene name)|psi-mi:Txn2(display_short)	psi-mi:acon_mouse(display_long)|uniprotkb:Citrate hydro-lyase(gene name synonym)|uniprotkb:Aco2(gene name)|psi-mi:Aco2(display_short)	psi-mi:"MI:0096"(pull down)	Chasapis et al. (2019)	pubmed:31018154|imex:IM-28571	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26500013|imex:IM-28571-23	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	intact:EBI-8354432(chain-parent)	refseq:NP_542364.1|ensembl:ENSMUSG00000022477(gene)|ensembl:ENSMUST00000023116(transcript)|go:"GO:0001889"(liver development)|go:"GO:0003994"(aconitate hydratase activity)|go:"GO:0005506"(iron ion binding)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0006099"(tricarboxylic acid cycle)|go:"GO:0006101"(citrate metabolic process)|go:"GO:0006102"(isocitrate metabolic process)|go:"GO:0035900"(response to isolation stress)|go:"GO:0043209"(myelin sheath)|go:"GO:0047780"(citrate dehydratase activity)|go:"GO:0051538"(3 iron, 4 sulfur cluster binding)|go:"GO:0051539"(4 iron, 4 sulfur cluster binding)|interpro:IPR000573(Aconitase A/isopropylmalate dehydratase small subunit, swivel)|interpro:IPR001030(Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha)|interpro:IPR006248(Aconitase, mitochondrial-like)|interpro:IPR015932(Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha, subdomain 2)|interpro:IPR018136|interpro:IPR036008|mint:Q99KI0|reactome:R-MMU-71403|interpro:IPR015928(Aconitase/3-isopropylmalate dehydratase, swivel)|interpro:IPR015931(Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha, subdomains 1 and 3)	-	chain-seq-start:60|chain-seq-end:166	-	figure legend:ST1.4 ST1.5 ST1.6|comment:DTT-eluted fraction|comment:The results in table 1.4,1.5 and 1.6 have been pooled together since they belong to the same experiment.|dataset:Rare diseases - Interactions investigated in the context of Rare genetic disease|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2020/12/04	2020/12/21	rogid:mvYK6+YgIN/WuGLBCWqsqPLfDyQ10090	rogid:0NOVcGhBwl4qmtnlhX9jcsQMdSo10090	rigid:U806iAk/nRbo20C3P3OsFasoYLY	false	mutation:34-34	-	-	-	psi-mi:"MI:0082"(peptide massfingerprinting)	psi-mi:"MI:0082"(peptide massfingerprinting)
uniprotkb:P97493-PRO_0000034151	uniprotkb:P47857	intact:EBI-26567598	intact:EBI-773630|uniprotkb:O35513|uniprotkb:Q543L1|uniprotkb:Q9JK94|uniprotkb:C8CMN5|uniprotkb:C8CMN6|uniprotkb:C8CMN7|ensembl:ENSMUSP00000059801|ensembl:ENSMUSP00000132803|ensembl:ENSMUSP00000155809	psi-mi:p97493-pro_0000034151(display_long)|uniprotkb:Thioredoxin-2(gene name synonym)|uniprotkb:Txn2(gene name)|psi-mi:Txn2(display_short)	psi-mi:pfkam_mouse(display_long)|uniprotkb:Phosphohexokinase(gene name synonym)|uniprotkb:Phosphofructo-1-kinase isozyme A(gene name synonym)|uniprotkb:Pfkm(gene name)|psi-mi:Pfkm(display_short)|uniprotkb:Pfka(gene name synonym)|uniprotkb:Pfk-m(gene name synonym)|uniprotkb:6-phosphofructokinase type A(gene name synonym)	psi-mi:"MI:0096"(pull down)	Chasapis et al. (2019)	pubmed:31018154|imex:IM-28571	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26500013|imex:IM-28571-23	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	intact:EBI-8354432(chain-parent)	refseq:NP_001156959.1|refseq:NP_001156960.1|refseq:NP_067489.3|refseq:XP_006520664.1|refseq:XP_006520665.1|ensembl:ENSMUSG00000033065(gene)|ensembl:ENSMUST00000051226(transcript)|ensembl:ENSMUST00000163507(transcript)|ensembl:ENSMUST00000230445(transcript)|go:"GO:0003872"(6-phosphofructokinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0005945"(6-phosphofructokinase complex)|go:"GO:0005980"(glycogen catabolic process)|go:"GO:0006002"(fructose 6-phosphate metabolic process)|go:"GO:0006096"(glycolytic process)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008443"(phosphofructokinase activity)|go:"GO:0016020"(membrane)|go:"GO:0016208"(AMP binding)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0019900"(kinase binding)|go:"GO:0030246"(carbohydrate binding)|go:"GO:0030388"(fructose 1,6-bisphosphate metabolic process)|go:"GO:0032024"(positive regulation of insulin secretion)|go:"GO:0042593"(glucose homeostasis)|go:"GO:0042802"(identical protein binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046716"(muscle cell cellular homeostasis)|go:"GO:0046872"(metal ion binding)|go:"GO:0048029"(monosaccharide binding)|go:"GO:0061615"(glycolytic process through fructose-6-phosphate)|go:"GO:0061621"(canonical glycolysis)|go:"GO:0070061"(fructose binding)|go:"GO:0070095"(fructose-6-phosphate binding)|go:"GO:0093001"(glycolysis from storage polysaccharide through glucose-1-phosphate)|go:"GO:0097228"(sperm principal piece)|interpro:IPR000023(Phosphofructokinase)|interpro:IPR009161(6-phosphofructokinase, eukaryotic type)|interpro:IPR015912(Phosphofructokinase, conserved site)|interpro:IPR022953|interpro:IPR035966|interpro:IPR041914|mint:P47857|reactome:R-MMU-70171	-	chain-seq-start:60|chain-seq-end:166	-	figure legend:ST1.4 ST1.5 ST1.6|comment:DTT-eluted fraction|comment:The results in table 1.4,1.5 and 1.6 have been pooled together since they belong to the same experiment.|dataset:Rare diseases - Interactions investigated in the context of Rare genetic disease|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2020/12/04	2020/12/21	rogid:mvYK6+YgIN/WuGLBCWqsqPLfDyQ10090	rogid:8pCfLb1VVqpKN2d+zr7NCnhWRBk10090	rigid:U806iAk/nRbo20C3P3OsFasoYLY	false	mutation:34-34	-	-	-	psi-mi:"MI:0082"(peptide massfingerprinting)	psi-mi:"MI:0082"(peptide massfingerprinting)
uniprotkb:P97493-PRO_0000034151	uniprotkb:Q60864	intact:EBI-26567598	intact:EBI-494437|uniprotkb:Q3TT16|uniprotkb:Q8BPH3|uniprotkb:Q99L66|ensembl:ENSMUSP00000025918	psi-mi:p97493-pro_0000034151(display_long)|uniprotkb:Thioredoxin-2(gene name synonym)|uniprotkb:Txn2(gene name)|psi-mi:Txn2(display_short)	psi-mi:stip1_mouse(display_long)|uniprotkb:Hsc70/Hsp90-organizing protein(gene name synonym)|uniprotkb:Stip1(gene name)|psi-mi:Stip1(display_short)	psi-mi:"MI:0096"(pull down)	Chasapis et al. (2019)	pubmed:31018154|imex:IM-28571	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26500013|imex:IM-28571-23	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	intact:EBI-8354432(chain-parent)	refseq:NP_058017.1|ensembl:ENSMUSG00000024966(gene)|ensembl:ENSMUST00000025918(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0030544"(Hsp70 protein binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0043209"(myelin sheath)|go:"GO:0051087"(chaperone binding)|go:"GO:0051879"(Hsp90 protein binding)|go:"GO:0098761"(cellular response to interleukin-7)|go:"GO:0101031"(chaperone complex)|go:"GO:0120293"(dynein axonemal particle)|interpro:IPR001440(Tetratricopeptide TPR-1)|interpro:IPR006636(Heat shock chaperonin-binding)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR019734|interpro:IPR041243|mint:Q60864|reactome:R-MMU-3371497|reactome:R-MMU-9696273	-	chain-seq-start:60|chain-seq-end:166	-	figure legend:ST1.4 ST1.5 ST1.6|comment:DTT-eluted fraction|comment:The results in table 1.4,1.5 and 1.6 have been pooled together since they belong to the same experiment.|dataset:Rare diseases - Interactions investigated in the context of Rare genetic disease|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2020/12/04	2020/12/21	rogid:mvYK6+YgIN/WuGLBCWqsqPLfDyQ10090	rogid:f6DTvAcA6tKSLqzw11r9X+rC8ao10090	rigid:U806iAk/nRbo20C3P3OsFasoYLY	false	mutation:34-34	-	-	-	psi-mi:"MI:0082"(peptide massfingerprinting)	psi-mi:"MI:0082"(peptide massfingerprinting)
uniprotkb:P97493-PRO_0000034151	uniprotkb:P38647	intact:EBI-26567598	intact:EBI-772469|uniprotkb:Q9CQ05|intact:EBI-4282065|uniprotkb:Q3TW93|uniprotkb:Q3UVN1|uniprotkb:Q3V015|intact:EBI-1635058|uniprotkb:Q7TSZ0|ensembl:ENSMUSP00000025217	psi-mi:p97493-pro_0000034151(display_long)|uniprotkb:Thioredoxin-2(gene name synonym)|uniprotkb:Txn2(gene name)|psi-mi:Txn2(display_short)	psi-mi:grp75_mouse(display_long)|uniprotkb:75 kDa glucose-regulated protein(gene name synonym)|uniprotkb:p66 MOT(gene name synonym)|uniprotkb:Heat shock 70 kDa protein 9(gene name synonym)|uniprotkb:Peptide-binding protein 74(gene name synonym)|uniprotkb:Mortalin(gene name synonym)|uniprotkb:Hspa9(gene name)|psi-mi:Hspa9(display_short)|uniprotkb:Grp75(gene name synonym)|uniprotkb:Hsp74(gene name synonym)|uniprotkb:Hspa9a(gene name synonym)	psi-mi:"MI:0096"(pull down)	Chasapis et al. (2019)	pubmed:31018154|imex:IM-28571	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26500013|imex:IM-28571-23	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	intact:EBI-8354432(chain-parent)	refseq:NP_034611.2|ensembl:ENSMUSG00000024359(gene)|ensembl:ENSMUST00000025217(transcript)|go:"GO:0005524"(ATP binding)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0006611"(protein export from nucleus)|go:"GO:0016226"(iron-sulfur cluster assembly)|go:"GO:0017134"(fibroblast growth factor binding)|go:"GO:0019899"(enzyme binding)|go:"GO:0030218"(erythrocyte differentiation)|go:"GO:0031072"(heat shock protein binding)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0034620"(cellular response to unfolded protein)|go:"GO:0042026"(protein refolding)|go:"GO:0042645"(mitochondrial nucleoid)|go:"GO:0043209"(myelin sheath)|go:"GO:0044183"(protein folding chaperone)|go:"GO:0045646"(regulation of erythrocyte differentiation)|go:"GO:0045647"(negative regulation of erythrocyte differentiation)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0051085"(chaperone cofactor-dependent protein refolding)|go:"GO:0051087"(chaperone binding)|go:"GO:0051787"(misfolded protein binding)|go:"GO:0060548"(negative regulation of cell death)|go:"GO:1902037"(negative regulation of hematopoietic stem cell differentiation)|go:"GO:1903707"(negative regulation of hemopoiesis)|interpro:IPR012725(Chaperone DnaK)|interpro:IPR013126(Heat shock protein 70)|interpro:IPR018181|interpro:IPR029047|interpro:IPR029048|interpro:IPR043129|mint:P38647|reactome:R-MMU-3371453	-	chain-seq-start:60|chain-seq-end:166	-	figure legend:ST1.4 ST1.5 ST1.6|comment:DTT-eluted fraction|comment:The results in table 1.4,1.5 and 1.6 have been pooled together since they belong to the same experiment.|dataset:Rare diseases - Interactions investigated in the context of Rare genetic disease|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2020/12/04	2020/12/21	rogid:mvYK6+YgIN/WuGLBCWqsqPLfDyQ10090	rogid:HyohIe5BGD5mW3UO0OekqUKOhbU10090	rigid:U806iAk/nRbo20C3P3OsFasoYLY	false	mutation:34-34	-	-	-	psi-mi:"MI:0082"(peptide massfingerprinting)	psi-mi:"MI:0082"(peptide massfingerprinting)
uniprotkb:P97493-PRO_0000034151	uniprotkb:O35226	intact:EBI-26567598	intact:EBI-992034|uniprotkb:Q91V59|uniprotkb:Q9JJM0|uniprotkb:Q9JJM1|uniprotkb:Q9JJM2|uniprotkb:Q9JJM3|ensembl:ENSMUSP00000102857	psi-mi:p97493-pro_0000034151(display_long)|uniprotkb:Thioredoxin-2(gene name synonym)|uniprotkb:Txn2(gene name)|psi-mi:Txn2(display_short)	psi-mi:psmd4_mouse(display_long)|uniprotkb:26S proteasome regulatory subunit S5A(gene name synonym)|uniprotkb:26S proteasome regulatory subunit RPN10(gene name synonym)|uniprotkb:Multiubiquitin chain-binding protein(gene name synonym)|uniprotkb:Psmd4(gene name)|psi-mi:Psmd4(display_short)|uniprotkb:Mcb1(gene name synonym)	psi-mi:"MI:0096"(pull down)	Chasapis et al. (2019)	pubmed:31018154|imex:IM-28571	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26500013|imex:IM-28571-23	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	intact:EBI-8354432(chain-parent)	refseq:NP_032977.1|ensembl:ENSMUSG00000005625(gene)|ensembl:ENSMUST00000107237(transcript)|go:"GO:0000502"(proteasome complex)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0008540"(proteasome regulatory particle, base subcomplex)|go:"GO:0022624"(proteasome accessory complex)|go:"GO:0031593"(polyubiquitin modification-dependent protein binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0043248"(proteasome assembly)|interpro:IPR003903(Ubiquitin interacting motif)|interpro:IPR002035(von Willebrand factor, type A)|interpro:IPR036465|mint:O35226|reactome:R-MMU-1169091|reactome:R-MMU-1234176|reactome:R-MMU-1236978|reactome:R-MMU-174084|reactome:R-MMU-174154|reactome:R-MMU-174178|reactome:R-MMU-174184|reactome:R-MMU-187577|reactome:R-MMU-195253|reactome:R-MMU-202424|reactome:R-MMU-2467813|reactome:R-MMU-2871837|reactome:R-MMU-349425|reactome:R-MMU-350562|reactome:R-MMU-382556|reactome:R-MMU-450408|reactome:R-MMU-4641257|reactome:R-MMU-4641258|reactome:R-MMU-5358346|reactome:R-MMU-5607761|reactome:R-MMU-5607764|reactome:R-MMU-5610780|reactome:R-MMU-5610785|reactome:R-MMU-5632684|reactome:R-MMU-5658442|reactome:R-MMU-5668541|reactome:R-MMU-5676590|reactome:R-MMU-5687128|reactome:R-MMU-5689603|reactome:R-MMU-5689880|reactome:R-MMU-68827|reactome:R-MMU-68949|reactome:R-MMU-69017|reactome:R-MMU-69481|reactome:R-MMU-69601|reactome:R-MMU-75815|reactome:R-MMU-8852276|reactome:R-MMU-8854050|reactome:R-MMU-8932339|reactome:R-MMU-4608870|reactome:R-MMU-8939236|reactome:R-MMU-8939902|reactome:R-MMU-8941858|reactome:R-MMU-8951664|reactome:R-MMU-9020702|reactome:R-MMU-983168|reactome:R-MMU-8948751|refseq:NP_001268946.1	-	chain-seq-start:60|chain-seq-end:166	-	figure legend:ST1.4 ST1.5 ST1.6|comment:DTT-eluted fraction|comment:The results in table 1.4,1.5 and 1.6 have been pooled together since they belong to the same experiment.|dataset:Rare diseases - Interactions investigated in the context of Rare genetic disease|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2020/12/04	2020/12/21	rogid:mvYK6+YgIN/WuGLBCWqsqPLfDyQ10090	rogid:foAsSSZ5pvYhKvPA4XUyZCVjo3010090	rigid:U806iAk/nRbo20C3P3OsFasoYLY	false	mutation:34-34	-	-	-	psi-mi:"MI:0082"(peptide massfingerprinting)	psi-mi:"MI:0082"(peptide massfingerprinting)
uniprotkb:P97493-PRO_0000034151	uniprotkb:P16858	intact:EBI-26567598	intact:EBI-444871|uniprotkb:Q0QEU0|uniprotkb:Q3THM2|uniprotkb:Q3TUI2|uniprotkb:Q3UMT2|uniprotkb:Q4V783|uniprotkb:Q569X2|uniprotkb:Q569X5|uniprotkb:Q5U410|uniprotkb:A6H6A8|ensembl:ENSMUSP00000073289|ensembl:ENSMUSP00000113213	psi-mi:p97493-pro_0000034151(display_long)|uniprotkb:Thioredoxin-2(gene name synonym)|uniprotkb:Txn2(gene name)|psi-mi:Txn2(display_short)	psi-mi:g3p_mouse(display_long)|uniprotkb:Gapdh(gene name)|psi-mi:Gapdh(display_short)|uniprotkb:Gapd(gene name synonym)|uniprotkb:Peptidyl-cysteine S-nitrosylase GAPDH(gene name synonym)	psi-mi:"MI:0096"(pull down)	Chasapis et al. (2019)	pubmed:31018154|imex:IM-28571	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26500013|imex:IM-28571-23	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	intact:EBI-8354432(chain-parent)	refseq:NP_032110.1|refseq:XP_001476757.1|ensembl:ENSMUSG00000057666(gene)|ensembl:ENSMUST00000073605(transcript)|ensembl:ENSMUST00000118875(transcript)|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0001819"(positive regulation of cytokine production)|go:"GO:0004365"("glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity")|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005811"(lipid droplet)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005975"(carbohydrate metabolic process)|go:"GO:0006094"(gluconeogenesis)|go:"GO:0006096"(glycolytic process)|go:"GO:0006915"(apoptotic process)|go:"GO:0008017"(microtubule binding)|go:"GO:0010951"(negative regulation of endopeptidase activity)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0017148"(negative regulation of translation)|go:"GO:0019828"(aspartic-type endopeptidase inhibitor activity)|go:"GO:0019899"(enzyme binding)|go:"GO:0019933"(cAMP-mediated signaling)|go:"GO:0031640"(killing of cells of another organism)|go:"GO:0031906"(late endosome lumen)|go:"GO:0031965"(nuclear membrane)|go:"GO:0032481"(positive regulation of type I interferon production)|go:"GO:0035605"(peptidyl-cysteine S-nitrosylase activity)|go:"GO:0035606"(peptidyl-cysteine S-trans-nitrosylation)|go:"GO:0042802"(identical protein binding)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043209"(myelin sheath)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0050661"(NADP binding)|go:"GO:0050821"(protein stabilization)|go:"GO:0050832"(defense response to fungus)|go:"GO:0051287"(NAD binding)|go:"GO:0051402"(neuron apoptotic process)|go:"GO:0051873"(killing by host of symbiont cells)|go:"GO:0060359"(response to ammonium ion)|go:"GO:0061844"(antimicrobial humoral immune response mediated by antimicrobial peptide)|go:"GO:0071346"(cellular response to interferon-gamma)|go:"GO:0097452"(GAIT complex)|go:"GO:0097718"(disordered domain specific binding)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099092"(postsynaptic density, intracellular component)|go:"GO:1905460"(negative regulation of vascular associated smooth muscle cell apoptotic process)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR006424(Glyceraldehyde-3-phosphate dehydrogenase, type I)|interpro:IPR020828|interpro:IPR020829|interpro:IPR020830|interpro:IPR020831|interpro:IPR036291|mint:P16858|rcsb pdb:6LGJ|rcsb pdb:6LGK|rcsb pdb:6LGM|reactome:R-MMU-70171|reactome:R-MMU-70263|refseq:NP_001276655.1|dip:DIP-31404N	-	chain-seq-start:60|chain-seq-end:166	-	figure legend:ST1.4 ST1.5 ST1.6|comment:DTT-eluted fraction|comment:The results in table 1.4,1.5 and 1.6 have been pooled together since they belong to the same experiment.|dataset:Rare diseases - Interactions investigated in the context of Rare genetic disease|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2020/12/04	2020/12/21	rogid:mvYK6+YgIN/WuGLBCWqsqPLfDyQ10090	rogid:SkcdXZ+143DDQFioo6mNWNpCLTI10090	rigid:U806iAk/nRbo20C3P3OsFasoYLY	false	mutation:34-34	-	-	-	psi-mi:"MI:0082"(peptide massfingerprinting)	psi-mi:"MI:0082"(peptide massfingerprinting)
uniprotkb:P97493-PRO_0000034151	uniprotkb:P16045	intact:EBI-26567598	intact:EBI-1634185|uniprotkb:P05163|uniprotkb:P11946|uniprotkb:P17601|uniprotkb:Q4FZH4|uniprotkb:Q99M27|uniprotkb:Q9D0X0|ensembl:ENSMUSP00000086795	psi-mi:p97493-pro_0000034151(display_long)|uniprotkb:Thioredoxin-2(gene name synonym)|uniprotkb:Txn2(gene name)|psi-mi:Txn2(display_short)	psi-mi:leg1_mouse(display_long)|uniprotkb:Lgals1(gene name)|psi-mi:Lgals1(display_short)|uniprotkb:Gbp(gene name synonym)|uniprotkb:Lectin galactoside-binding soluble 1(gene name synonym)|uniprotkb:Beta-galactoside-binding lectin L-14-I(gene name synonym)|uniprotkb:S-Lac lectin 1(gene name synonym)|uniprotkb:Galaptin(gene name synonym)|uniprotkb:14 kDa lectin(gene name synonym)|uniprotkb:Lactose-binding lectin 1(gene name synonym)	psi-mi:"MI:0096"(pull down)	Chasapis et al. (2019)	pubmed:31018154|imex:IM-28571	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26500013|imex:IM-28571-23	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	intact:EBI-8354432(chain-parent)	refseq:NP_032521.1|ensembl:ENSMUSG00000068220(gene)|ensembl:ENSMUST00000089377(transcript)|go:"GO:0002317"(plasma cell differentiation)|go:"GO:0005534"(galactose binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006915"(apoptotic process)|go:"GO:0007157"(heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules)|go:"GO:0009986"(cell surface)|go:"GO:0010812"(negative regulation of cell-substrate adhesion)|go:"GO:0010977"(negative regulation of neuron projection development)|go:"GO:0030246"(carbohydrate binding)|go:"GO:0030395"(lactose binding)|go:"GO:0031295"(T cell costimulation)|go:"GO:0034120"(positive regulation of erythrocyte aggregation)|go:"GO:0035900"(response to isolation stress)|go:"GO:0042493"|go:"GO:0042802"(identical protein binding)|go:"GO:0043236"(laminin binding)|go:"GO:0045445"(myoblast differentiation)|go:"GO:0046598"(positive regulation of viral entry into host cell)|go:"GO:0048678"(response to axon injury)|go:"GO:0062023"(collagen-containing extracellular matrix)|go:"GO:0071333"(cellular response to glucose stimulus)|go:"GO:0071407"(cellular response to organic cyclic compound)|interpro:IPR001079(Galectin, galactose-binding lectin)|interpro:IPR013320(Concanavalin A-like lectin/glucanase, subgroup)|interpro:IPR044156|mint:P16045|rcsb pdb:4LBQ|reactome:R-MMU-381426|reactome:R-MMU-8957275	-	chain-seq-start:60|chain-seq-end:166	-	figure legend:ST1.4 ST1.5 ST1.6|comment:DTT-eluted fraction|comment:The results in table 1.4,1.5 and 1.6 have been pooled together since they belong to the same experiment.|dataset:Rare diseases - Interactions investigated in the context of Rare genetic disease|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2020/12/04	2020/12/21	rogid:mvYK6+YgIN/WuGLBCWqsqPLfDyQ10090	rogid:VMxhs6wVhql3NEex38RQeIwirZs10090	rigid:U806iAk/nRbo20C3P3OsFasoYLY	false	mutation:34-34	-	-	-	psi-mi:"MI:0082"(peptide massfingerprinting)	psi-mi:"MI:0082"(peptide massfingerprinting)
uniprotkb:P97493-PRO_0000034151	uniprotkb:Q6P8J7	intact:EBI-26567598	intact:EBI-20565591|ensembl:ENSMUSP00000022122	psi-mi:p97493-pro_0000034151(display_long)|uniprotkb:Thioredoxin-2(gene name synonym)|uniprotkb:Txn2(gene name)|psi-mi:Txn2(display_short)	psi-mi:kcrs_mouse(display_long)|uniprotkb:Basic-type mitochondrial creatine kinase(gene name synonym)|uniprotkb:Sarcomeric mitochondrial creatine kinase(gene name synonym)|uniprotkb:Ckmt2(gene name)|psi-mi:Ckmt2(display_short)	psi-mi:"MI:0096"(pull down)	Chasapis et al. (2019)	pubmed:31018154|imex:IM-28571	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26500013|imex:IM-28571-23	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	intact:EBI-8354432(chain-parent)	refseq:NP_940807.1|ensembl:ENSMUSG00000021622(gene)|ensembl:ENSMUST00000022122(transcript)|go:"GO:0004111"(creatine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0006603"(phosphocreatine metabolic process)|go:"GO:0016301"(kinase activity)|go:"GO:0046314"(phosphocreatine biosynthetic process)|go:"GO:1901612"(cardiolipin binding)|interpro:IPR000749("ATP:guanido phosphotransferase")|interpro:IPR014746(Glutamine synthetase/guanido kinase, catalytic region)|interpro:IPR022413|interpro:IPR022414|interpro:IPR022415|interpro:IPR036802|mint:Q6P8J7|reactome:R-MMU-71288	-	chain-seq-start:60|chain-seq-end:166	-	figure legend:ST1.4 ST1.5 ST1.6|comment:DTT-eluted fraction|comment:The results in table 1.4,1.5 and 1.6 have been pooled together since they belong to the same experiment.|dataset:Rare diseases - Interactions investigated in the context of Rare genetic disease|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2020/12/04	2020/12/21	rogid:mvYK6+YgIN/WuGLBCWqsqPLfDyQ10090	rogid:WiCiHk8tlPTl97O2Pj1PBFf3Ifs10090	rigid:U806iAk/nRbo20C3P3OsFasoYLY	false	mutation:34-34	-	-	-	psi-mi:"MI:0082"(peptide massfingerprinting)	psi-mi:"MI:0082"(peptide massfingerprinting)
uniprotkb:P97493-PRO_0000034151	uniprotkb:P07310	intact:EBI-26567598	intact:EBI-299493|ensembl:ENSMUSP00000146972	psi-mi:p97493-pro_0000034151(display_long)|uniprotkb:Thioredoxin-2(gene name synonym)|uniprotkb:Txn2(gene name)|psi-mi:Txn2(display_short)	psi-mi:kcrm_mouse(display_long)|uniprotkb:Ckm(gene name)|psi-mi:Ckm(display_short)|uniprotkb:Ckmm(gene name synonym)|uniprotkb:Creatine kinase M chain(gene name synonym)|uniprotkb:M-CK(gene name synonym)|uniprotkb:Creatine phosphokinase M-type(gene name synonym)	psi-mi:"MI:0096"(pull down)	Chasapis et al. (2019)	pubmed:31018154|imex:IM-28571	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26500013|imex:IM-28571-23	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	intact:EBI-8354432(chain-parent)	ensembl:ENSMUSG00000030399(gene)|ensembl:ENSMUST00000208710(transcript)|go:"GO:0004111"(creatine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005737"(cytoplasm)|go:"GO:0006603"(phosphocreatine metabolic process)|go:"GO:0009408"(response to heat)|go:"GO:0016301"(kinase activity)|go:"GO:0046314"(phosphocreatine biosynthetic process)|interpro:IPR000749("ATP:guanido phosphotransferase")|interpro:IPR014746(Glutamine synthetase/guanido kinase, catalytic region)|interpro:IPR022413|interpro:IPR022414|interpro:IPR022415|interpro:IPR036802|mint:P07310|reactome:R-MMU-71288|refseq:NP_031736.1	-	chain-seq-start:60|chain-seq-end:166	-	figure legend:ST1.4 ST1.5 ST1.6|comment:DTT-eluted fraction|comment:The results in table 1.4,1.5 and 1.6 have been pooled together since they belong to the same experiment.|dataset:Rare diseases - Interactions investigated in the context of Rare genetic disease|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2020/12/04	2020/12/21	rogid:mvYK6+YgIN/WuGLBCWqsqPLfDyQ10090	rogid:HUwtOLpKEeqrxa326Rz+yjZ6/Mo10090	rigid:U806iAk/nRbo20C3P3OsFasoYLY	false	mutation:34-34	-	-	-	psi-mi:"MI:0082"(peptide massfingerprinting)	psi-mi:"MI:0082"(peptide massfingerprinting)
uniprotkb:P97493-PRO_0000034151	uniprotkb:P16015	intact:EBI-26567598	intact:EBI-761937|uniprotkb:Q9ERN8|ensembl:ENSMUSP00000029076	psi-mi:p97493-pro_0000034151(display_long)|uniprotkb:Thioredoxin-2(gene name synonym)|uniprotkb:Txn2(gene name)|psi-mi:Txn2(display_short)	psi-mi:cah3_mouse(display_long)|uniprotkb:Carbonic anhydrase III(gene name synonym)|uniprotkb:Carbonate dehydratase III(gene name synonym)|uniprotkb:Ca3(gene name)|psi-mi:Ca3(display_short)|uniprotkb:Car3(gene name synonym)	psi-mi:"MI:0096"(pull down)	Chasapis et al. (2019)	pubmed:31018154|imex:IM-28571	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26500013|imex:IM-28571-23	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	intact:EBI-8354432(chain-parent)	refseq:NP_031632.2|ensembl:ENSMUST00000029076(transcript)|go:"GO:0004089"(carbonate dehydratase activity)|go:"GO:0005829"(cytosol)|go:"GO:0006730"(one-carbon metabolic process)|go:"GO:0006979"(response to oxidative stress)|go:"GO:0008270"(zinc ion binding)|go:"GO:0009617"(response to bacterium)|go:"GO:0016151"(nickel cation binding)|go:"GO:0016791"(phosphatase activity)|go:"GO:0016836"(hydro-lyase activity)|go:"GO:0045471"(response to ethanol)|interpro:IPR001148(Carbonic anhydrase, eukaryotic)|interpro:IPR018338|interpro:IPR018441|interpro:IPR023561|interpro:IPR036398|mint:P16015|reactome:R-MMU-1475029|ensembl:ENSMUSG00000027559(gene)	-	chain-seq-start:60|chain-seq-end:166	-	figure legend:ST1.4 ST1.5 ST1.6|comment:DTT-eluted fraction|comment:The results in table 1.4,1.5 and 1.6 have been pooled together since they belong to the same experiment.|dataset:Rare diseases - Interactions investigated in the context of Rare genetic disease|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2020/12/04	2020/12/21	rogid:mvYK6+YgIN/WuGLBCWqsqPLfDyQ10090	rogid:76FGpCFeQ8TYZLk/x+/XDyMuEqQ10090	rigid:U806iAk/nRbo20C3P3OsFasoYLY	false	mutation:34-34	-	-	-	psi-mi:"MI:0082"(peptide massfingerprinting)	psi-mi:"MI:0082"(peptide massfingerprinting)
uniprotkb:P97493-PRO_0000034151	uniprotkb:Q9R0Y5	intact:EBI-26567598	intact:EBI-777466|uniprotkb:A2AK80|uniprotkb:Q542C5|uniprotkb:Q9R0Y4|ensembl:ENSMUSP00000108902|ensembl:ENSMUSP00000108903	psi-mi:p97493-pro_0000034151(display_long)|uniprotkb:Thioredoxin-2(gene name synonym)|uniprotkb:Txn2(gene name)|psi-mi:Txn2(display_short)	psi-mi:kad1_mouse(display_long)|uniprotkb:ATP-AMP transphosphorylase 1(gene name synonym)|uniprotkb:Myokinase(gene name synonym)|uniprotkb:Ak1(gene name)|psi-mi:Ak1(display_short)|uniprotkb:"ATP:AMP phosphotransferase"(gene name synonym)|uniprotkb:Adenylate monophosphate kinase(gene name synonym)	psi-mi:"MI:0096"(pull down)	Chasapis et al. (2019)	pubmed:31018154|imex:IM-28571	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26500013|imex:IM-28571-23	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	intact:EBI-8354432(chain-parent)	refseq:NP_001185719.1|refseq:NP_001185720.1|refseq:NP_001185721.1|refseq:NP_067490.1|refseq:XP_006497687.1|ensembl:ENSMUSG00000026817(gene)|ensembl:ENSMUST00000113277(transcript)|ensembl:ENSMUST00000113278(transcript)|go:"GO:0001520"(outer dense fiber)|go:"GO:0004017"(adenylate kinase activity)|go:"GO:0004550"(nucleoside diphosphate kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006165"(nucleoside diphosphate phosphorylation)|go:"GO:0006172"(ADP biosynthetic process)|go:"GO:0009142"(nucleoside triphosphate biosynthetic process)|go:"GO:0010828"(positive regulation of glucose transmembrane transport)|go:"GO:0030017"(sarcomere)|go:"GO:0036126"(sperm flagellum)|go:"GO:0043005"(neuron projection)|go:"GO:0046033"(AMP metabolic process)|go:"GO:0046034"(ATP metabolic process)|go:"GO:0046103"(inosine biosynthetic process)|go:"GO:0048471"(perinuclear region of cytoplasm)|interpro:IPR000850(Adenylate kinase)|interpro:IPR006267(Adenylate kinase, isozyme 1)|interpro:IPR027417|interpro:IPR028582|interpro:IPR033690|mint:Q9R0Y5|reactome:R-MMU-499943	-	chain-seq-start:60|chain-seq-end:166	-	figure legend:ST1.4 ST1.5 ST1.6|comment:DTT-eluted fraction|comment:The results in table 1.4,1.5 and 1.6 have been pooled together since they belong to the same experiment.|dataset:Rare diseases - Interactions investigated in the context of Rare genetic disease|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2020/12/04	2020/12/21	rogid:mvYK6+YgIN/WuGLBCWqsqPLfDyQ10090	rogid:HTydMeIFNEaVZDs7sEN7aLieuVg10090	rigid:U806iAk/nRbo20C3P3OsFasoYLY	false	mutation:34-34	-	-	-	psi-mi:"MI:0082"(peptide massfingerprinting)	psi-mi:"MI:0082"(peptide massfingerprinting)
uniprotkb:P97493-PRO_0000034151	uniprotkb:P63038	intact:EBI-26567598	intact:EBI-299343|ensembl:ENSMUSP00000027123|uniprotkb:P19226|uniprotkb:P19227|uniprotkb:P97602|uniprotkb:Q3KQP2|uniprotkb:Q3UIP0|uniprotkb:Q8C2C7|uniprotkb:Q8VEF4	psi-mi:p97493-pro_0000034151(display_long)|uniprotkb:Thioredoxin-2(gene name synonym)|uniprotkb:Txn2(gene name)|psi-mi:Txn2(display_short)	psi-mi:ch60_mouse(display_long)|uniprotkb:Hspd1(gene name)|psi-mi:Hspd1(display_short)|uniprotkb:Hsp60(gene name synonym)|uniprotkb:Heat shock protein 60(gene name synonym)|uniprotkb:60 kDa chaperonin(gene name synonym)|uniprotkb:Chaperonin 60(gene name synonym)|uniprotkb:Mitochondrial matrix protein P1(gene name synonym)|uniprotkb:HSP-65(gene name synonym)	psi-mi:"MI:0096"(pull down)	Chasapis et al. (2019)	pubmed:31018154|imex:IM-28571	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26500013|imex:IM-28571-23	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	intact:EBI-8354432(chain-parent)	ensembl:ENSMUSG00000025980(gene)|ensembl:ENSMUST00000027123(transcript)|go:"GO:0001530"(lipopolysaccharide binding)|go:"GO:0001666"(response to hypoxia)|go:"GO:0002039"(p53 binding)|go:"GO:0002755"(MyD88-dependent toll-like receptor signaling pathway)|go:"GO:0002842"(positive regulation of T cell mediated immune response to tumor cell)|go:"GO:0002931"(response to ischemia)|go:"GO:0003725"(double-stranded RNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0005769"(early endosome)|go:"GO:0005782"(peroxisomal matrix)|go:"GO:0005791"(rough endoplasmic reticulum)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005905"(clathrin-coated pit)|go:"GO:0006457"(protein folding)|go:"GO:0006919"(activation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0006986"(response to unfolded protein)|go:"GO:0008035"(high-density lipoprotein particle binding)|go:"GO:0008637"(apoptotic mitochondrial changes)|go:"GO:0009409"(response to cold)|go:"GO:0009986"(cell surface)|go:"GO:0014823"(response to activity)|go:"GO:0016020"(membrane)|go:"GO:0016853"(isomerase activity)|go:"GO:0019899"(enzyme binding)|go:"GO:0030061"(mitochondrial crista)|go:"GO:0030135"(coated vesicle)|go:"GO:0030141"(secretory granule)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0031985"(Golgi cisterna)|go:"GO:0032496"(response to lipopolysaccharide)|go:"GO:0032727"(positive regulation of interferon-alpha production)|go:"GO:0032729"(positive regulation of interferon-gamma production)|go:"GO:0032733"(positive regulation of interleukin-10 production)|go:"GO:0032735"(positive regulation of interleukin-12 production)|go:"GO:0032755"(positive regulation of interleukin-6 production)|go:"GO:0032760"(positive regulation of tumor necrosis factor production)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033198"(response to ATP)|go:"GO:0034185"(apolipoprotein binding)|go:"GO:0034186"(apolipoprotein A-I binding)|go:"GO:0034514"(mitochondrial unfolded protein response)|go:"GO:0034605"(cellular response to heat)|go:"GO:0042026"(protein refolding)|go:"GO:0042100"(B cell proliferation)|go:"GO:0042110"(T cell activation)|go:"GO:0042113"(B cell activation)|go:"GO:0042220"(response to cocaine)|go:"GO:0042493"|go:"GO:0042542"(response to hydrogen peroxide)|go:"GO:0042588"(zymogen granule)|go:"GO:0043032"(positive regulation of macrophage activation)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043209"(myelin sheath)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0043627"(response to estrogen)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045041"(protein import into mitochondrial intermembrane space)|go:"GO:0045121"(membrane raft)|go:"GO:0046696"(lipopolysaccharide receptor complex)|go:"GO:0048291"(isotype switching to IgG isotypes)|go:"GO:0050729"(positive regulation of inflammatory response)|go:"GO:0050821"(protein stabilization)|go:"GO:0050870"(positive regulation of T cell activation)|go:"GO:0051087"(chaperone binding)|go:"GO:0051384"(response to glucocorticoid)|go:"GO:0051702"(biological process involved in interaction with symbiont)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071866"(negative regulation of apoptotic process in bone marrow cell)|go:"GO:0097225"(sperm midpiece)|go:"GO:0098761"(cellular response to interleukin-7)|go:"GO:0140030"(modification-dependent protein binding)|go:"GO:1903427"(negative regulation of reactive oxygen species biosynthetic process)|interpro:IPR001844(Chaperonin Cpn60)|interpro:IPR002423(Chaperonin Cpn60/TCP-1)|interpro:IPR018370|interpro:IPR027409|interpro:IPR027410|interpro:IPR027413|mint:P63038|reactome:R-MMU-1268020|refseq:XP_006495769.1|refseq:NP_034607.3|dip:DIP-31396N	-	chain-seq-start:60|chain-seq-end:166	-	figure legend:ST1.4 ST1.5 ST1.6|comment:DTT-eluted fraction|comment:The results in table 1.4,1.5 and 1.6 have been pooled together since they belong to the same experiment.|dataset:Rare diseases - Interactions investigated in the context of Rare genetic disease|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2020/12/04	2020/12/21	rogid:mvYK6+YgIN/WuGLBCWqsqPLfDyQ10090	rogid:WD1fQLh4I0ovpakE8KtM1R0XpL410090	rigid:U806iAk/nRbo20C3P3OsFasoYLY	false	mutation:34-34	-	-	-	psi-mi:"MI:0082"(peptide massfingerprinting)	psi-mi:"MI:0082"(peptide massfingerprinting)
uniprotkb:P97493-PRO_0000034151	uniprotkb:P20108	intact:EBI-26567598	intact:EBI-309031|ensembl:ENSMUSP00000025961	psi-mi:p97493-pro_0000034151(display_long)|uniprotkb:Thioredoxin-2(gene name synonym)|uniprotkb:Txn2(gene name)|psi-mi:Txn2(display_short)	psi-mi:prdx3_mouse(display_long)|uniprotkb:Prdx3(gene name)|psi-mi:Prdx3(display_short)|uniprotkb:Aop1(gene name synonym)|uniprotkb:Mer5(gene name synonym)|uniprotkb:Perioredoxin-3(gene name synonym)|uniprotkb:PRX III(gene name synonym)|uniprotkb:Antioxidant protein 1(gene name synonym)|uniprotkb:Protein MER5(gene name synonym)|uniprotkb:Thioredoxin-dependent peroxiredoxin 3(gene name synonym)	psi-mi:"MI:0096"(pull down)	Chasapis et al. (2019)	pubmed:31018154|imex:IM-28571	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26500013|imex:IM-28571-23	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	intact:EBI-8354432(chain-parent)	ensembl:ENSMUSG00000024997(gene)|ensembl:ENSMUST00000025961(transcript)|go:"GO:0001893"(maternal placenta development)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005769"(early endosome)|go:"GO:0005829"(cytosol)|go:"GO:0006979"(response to oxidative stress)|go:"GO:0007005"(mitochondrion organization)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0008379"(thioredoxin peroxidase activity)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0018171"(peptidyl-cysteine oxidation)|go:"GO:0043209"(myelin sheath)|go:"GO:0019900"(kinase binding)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0045454"(cell redox homeostasis)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|go:"GO:0051881"(regulation of mitochondrial membrane potential)|interpro:IPR000866(Alkyl hydroperoxide reductase/ Thiol specific antioxidant/ Mal allergen)|interpro:IPR013766(Thioredoxin domain)|interpro:IPR019479|interpro:IPR036249|mint:P20108|reactome:R-MMU-3299685|go:"GO:0019901"(protein kinase binding)|go:"GO:0030099"(myeloid cell differentiation)|go:"GO:0032496"(response to lipopolysaccharide)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033673"(negative regulation of kinase activity)|go:"GO:0034599"(cellular response to oxidative stress)|go:"GO:0034614"(cellular response to reactive oxygen species)|go:"GO:0042542"(response to hydrogen peroxide)|go:"GO:0042744"(hydrogen peroxide catabolic process)|go:"GO:0042802"(identical protein binding)|go:"GO:0043027"(cysteine-type endopeptidase inhibitor activity involved in apoptotic process)|refseq:NP_031478.1	-	chain-seq-start:60|chain-seq-end:166	-	figure legend:ST1.4 ST1.5 ST1.6|comment:DTT-eluted fraction|comment:The results in table 1.4,1.5 and 1.6 have been pooled together since they belong to the same experiment.|dataset:Rare diseases - Interactions investigated in the context of Rare genetic disease|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2020/12/04	2020/12/21	rogid:mvYK6+YgIN/WuGLBCWqsqPLfDyQ10090	rogid:BGMQPun3/Vu7SSlj8rdWV+PU48Q10090	rigid:U806iAk/nRbo20C3P3OsFasoYLY	false	mutation:34-34	-	-	-	psi-mi:"MI:0082"(peptide massfingerprinting)	psi-mi:"MI:0082"(peptide massfingerprinting)
uniprotkb:P97493-PRO_0000034151	uniprotkb:Q99LX0	intact:EBI-26567598	intact:EBI-1634273|uniprotkb:O88306|uniprotkb:Q3THB9|uniprotkb:Q3U509|ensembl:ENSMUSP00000030805|ensembl:ENSMUSP00000101298|ensembl:ENSMUSP00000101299|ensembl:ENSMUSP00000101300	psi-mi:p97493-pro_0000034151(display_long)|uniprotkb:Thioredoxin-2(gene name synonym)|uniprotkb:Txn2(gene name)|psi-mi:Txn2(display_short)	psi-mi:park7_mouse(display_long)|uniprotkb:Park7(gene name)|psi-mi:Park7(display_short)|uniprotkb:Protein/nucleic acid deglycase DJ-1(gene name synonym)|uniprotkb:Maillard deglycase(gene name synonym)|uniprotkb:Parkinsonism-associated deglycase(gene name synonym)|uniprotkb:Protein DJ-1(gene name synonym)	psi-mi:"MI:0096"(pull down)	Chasapis et al. (2019)	pubmed:31018154|imex:IM-28571	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26500013|imex:IM-28571-23	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	intact:EBI-8354432(chain-parent)	refseq:NP_065594.2|go:"GO:1903428"(positive regulation of reactive oxygen species biosynthetic process)|go:"GO:1904782"(negative regulation of NMDA glutamate receptor activity)|go:"GO:1905259"(negative regulation of nitrosative stress-induced intrinsic apoptotic signaling pathway)|go:"GO:1905516"(positive regulation of fertilization)|go:"GO:1990381"(ubiquitin-specific protease binding)|go:"GO:1990422"("glyoxalase (glycolic acid-forming) activity")|go:"GO:2000157"(negative regulation of ubiquitin-specific protease activity)|go:"GO:2000277"(positive regulation of oxidative phosphorylation uncoupler activity)|go:"GO:2000679"(positive regulation of transcription regulatory region DNA binding)|go:"GO:2000825"(positive regulation of androgen receptor activity)|go:"GO:2001237"(negative regulation of extrinsic apoptotic signaling pathway)|go:"GO:2001268"(negative regulation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway)|interpro:IPR002818(ThiJ/PfpI)|interpro:IPR006287(DJ-1)|interpro:IPR029062|mint:Q99LX0|reactome:R-MMU-3899300|reactome:R-MMU-9646399|ensembl:ENSMUSG00000028964(gene)|ensembl:ENSMUST00000030805(transcript)|ensembl:ENSMUST00000105673(transcript)|ensembl:ENSMUST00000105674(transcript)|ensembl:ENSMUST00000105675(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0001933"(negative regulation of protein phosphorylation)|go:"GO:0001963"(synaptic transmission, dopaminergic)|go:"GO:0002866"(positive regulation of acute inflammatory response to antigenic stimulus)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005507"(copper ion binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005758"(mitochondrial intermembrane space)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006281"(DNA repair)|go:"GO:0006469"(negative regulation of protein kinase activity)|go:"GO:0006517"(protein deglycosylation)|go:"GO:0006914"(autophagy)|go:"GO:0006954"(inflammatory response)|go:"GO:0006979"(response to oxidative stress)|go:"GO:0007005"(mitochondrion organization)|go:"GO:0007338"(single fertilization)|go:"GO:0008233"(peptidase activity)|go:"GO:0008344"(adult locomotory behavior)|go:"GO:0010273"(detoxification of copper ion)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0016532"(superoxide dismutase copper chaperone activity)|go:"GO:0016570"(histone modification)|go:"GO:0016605"(PML body)|go:"GO:0016684"(oxidoreductase activity, acting on peroxide as acceptor)|go:"GO:0019249"(lactate biosynthetic process)|go:"GO:0019826"(oxygen sensor activity)|go:"GO:0019899"(enzyme binding)|go:"GO:0019900"(kinase binding)|go:"GO:0019955"(cytokine binding)|go:"GO:0030073"(insulin secretion)|go:"GO:0030424"(axon)|go:"GO:0031334"(positive regulation of protein-containing complex assembly)|go:"GO:0031397"(negative regulation of protein ubiquitination)|go:"GO:0032091"(negative regulation of protein binding)|go:"GO:0032435"(negative regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0032757"(positive regulation of interleukin-8 production)|go:"GO:0033138"(positive regulation of peptidyl-serine phosphorylation)|go:"GO:0033182"(regulation of histone ubiquitination)|go:"GO:0033234"(negative regulation of protein sumoylation)|go:"GO:0033864"("positive regulation of NAD(P)H oxidase activity")|go:"GO:0034599"(cellular response to oxidative stress)|go:"GO:0034614"(cellular response to reactive oxygen species)|go:"GO:0035065"(regulation of histone acetylation)|go:"GO:0036470"(tyrosine 3-monooxygenase activator activity)|go:"GO:0036471"(cellular response to glyoxal)|go:"GO:0036478"(L-dopa decarboxylase activator activity)|go:"GO:0036524"(protein deglycase activity)|go:"GO:0036526"(peptidyl-cysteine deglycation)|go:"GO:0036527"(peptidyl-arginine deglycation)|go:"GO:0036528"(peptidyl-lysine deglycation)|go:"GO:0036529"(protein deglycation, glyoxal removal)|go:"GO:0036530"(protein deglycation, methylglyoxal removal)|go:"GO:0036531"(glutathione deglycation)|go:"GO:0042177"(negative regulation of protein catabolic process)|go:"GO:0042542"(response to hydrogen peroxide)|go:"GO:0042593"(glucose homeostasis)|go:"GO:0042743"(hydrogen peroxide metabolic process)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043005"(neuron projection)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043523"(regulation of neuron apoptotic process)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0044297"(cell body)|go:"GO:0044388"(small protein activating enzyme binding)|go:"GO:0044390"(ubiquitin-like protein conjugating enzyme binding)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045121"(membrane raft)|go:"GO:0045340"(mercury ion binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046295"(glycolate biosynthetic process)|go:"GO:0046826"(negative regulation of protein export from nucleus)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0050681"(androgen receptor binding)|go:"GO:0050727"(regulation of inflammatory response)|go:"GO:0050787"(detoxification of mercury ion)|go:"GO:0050821"(protein stabilization)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0051444"(negative regulation of ubiquitin-protein transferase activity)|go:"GO:0051583"(dopamine uptake involved in synaptic transmission)|go:"GO:0051881"(regulation of mitochondrial membrane potential)|go:"GO:0051899"(membrane depolarization)|go:"GO:0051920"(peroxiredoxin activity)|go:"GO:0060081"(membrane hyperpolarization)|go:"GO:0060548"(negative regulation of cell death)|go:"GO:0060765"(regulation of androgen receptor signaling pathway)|go:"GO:0061727"(methylglyoxal catabolic process to lactate)|go:"GO:0061827"(sperm head)|go:"GO:0070301"(cellular response to hydrogen peroxide)|go:"GO:0070994"(detection of oxidative stress)|go:"GO:0097110"(scaffold protein binding)|go:"GO:0098793"(presynapse)|go:"GO:0106044"(guanine deglycation)|go:"GO:0106045"(guanine deglycation, methylglyoxal removal)|go:"GO:0106046"(guanine deglycation, glyoxal removal)|go:"GO:0110095"(cellular detoxification of aldehyde)|go:"GO:0140041"(cellular detoxification of methylglyoxal)|go:"GO:0140297"(DNA-binding transcription factor binding)|go:"GO:1900182"(positive regulation of protein localization to nucleus)|go:"GO:1901215"(negative regulation of neuron death)|go:"GO:1901671"(positive regulation of superoxide dismutase activity)|go:"GO:1901984"(negative regulation of protein acetylation)|go:"GO:1902177"(positive regulation of oxidative stress-induced intrinsic apoptotic signaling pathway)|go:"GO:1902236"(negative regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway)|go:"GO:1902958"(positive regulation of mitochondrial electron transport, NADH to ubiquinone)|go:"GO:1903094"(negative regulation of protein K48-linked deubiquitination)|go:"GO:1903122"(negative regulation of TRAIL-activated apoptotic signaling pathway)|go:"GO:1903135"(cupric ion binding)|go:"GO:1903136"(cuprous ion binding)|go:"GO:1903168"(positive regulation of pyrroline-5-carboxylate reductase activity)|go:"GO:1903178"(positive regulation of tyrosine 3-monooxygenase activity)|go:"GO:1903181"(positive regulation of dopamine biosynthetic process)|go:"GO:1903189"(glyoxal metabolic process)|go:"GO:1903197"(positive regulation of L-dopa biosynthetic process)|go:"GO:1903200"(positive regulation of L-dopa decarboxylase activity)|go:"GO:1903202"(negative regulation of oxidative stress-induced cell death)|go:"GO:1903204"(negative regulation of oxidative stress-induced neuron death)|go:"GO:1903206"(negative regulation of hydrogen peroxide-induced cell death)|go:"GO:1903208"(negative regulation of hydrogen peroxide-induced neuron death)|go:"GO:1903377"(negative regulation of oxidative stress-induced neuron intrinsic apoptotic signaling pathway)|go:"GO:1903384"(negative regulation of hydrogen peroxide-induced neuron intrinsic apoptotic signaling pathway)|go:"GO:1903427"(negative regulation of reactive oxygen species biosynthetic process)	-	chain-seq-start:60|chain-seq-end:166	-	figure legend:ST1.4 ST1.5 ST1.6|comment:DTT-eluted fraction|comment:The results in table 1.4,1.5 and 1.6 have been pooled together since they belong to the same experiment.|dataset:Rare diseases - Interactions investigated in the context of Rare genetic disease|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2020/12/04	2020/12/21	rogid:mvYK6+YgIN/WuGLBCWqsqPLfDyQ10090	rogid:dfkL4WeM+WgrYJa3aYTWbFyi0bk10090	rigid:U806iAk/nRbo20C3P3OsFasoYLY	false	mutation:34-34	-	-	-	psi-mi:"MI:0082"(peptide massfingerprinting)	psi-mi:"MI:0082"(peptide massfingerprinting)
uniprotkb:P97493-PRO_0000034151	uniprotkb:O08709	intact:EBI-26567598	intact:EBI-444895|uniprotkb:Q91WT2|uniprotkb:Q9QWP4|uniprotkb:Q9QWW0	psi-mi:p97493-pro_0000034151(display_long)|uniprotkb:Thioredoxin-2(gene name synonym)|uniprotkb:Txn2(gene name)|psi-mi:Txn2(display_short)	psi-mi:prdx6_mouse(display_long)|uniprotkb:Lysophosphatidylcholine acyltransferase 5(gene name synonym)|uniprotkb:Glutathione-dependent peroxiredoxin(gene name synonym)|uniprotkb:Antioxidant protein 2(gene name synonym)|uniprotkb:1-Cys peroxiredoxin(gene name synonym)|uniprotkb:Acidic calcium-independent phospholipase A2(gene name synonym)|uniprotkb:Non-selenium glutathione peroxidase(gene name synonym)|uniprotkb:Prdx6(gene name)|psi-mi:Prdx6(display_short)|uniprotkb:Aop2(gene name synonym)|uniprotkb:Ltw4(gene name synonym)|uniprotkb:Prdx5(gene name synonym)	psi-mi:"MI:0096"(pull down)	Chasapis et al. (2019)	pubmed:31018154|imex:IM-28571	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26500013|imex:IM-28571-23	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	intact:EBI-8354432(chain-parent)	refseq:NP_031479.1|interpro:IPR000866(Alkyl hydroperoxide reductase/ Thiol specific antioxidant/ Mal allergen)|interpro:IPR024706|interpro:IPR019479|go:"GO:0000302"(response to reactive oxygen species)|go:"GO:0004601"(peroxidase activity)|go:"GO:0004602"(glutathione peroxidase activity)|go:"GO:0004623"(phospholipase A2 activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005764"(lysosome)|go:"GO:0005829"(cytosol)|go:"GO:0006979"(response to oxidative stress)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032060"(bleb assembly)|go:"GO:0042744"(hydrogen peroxide catabolic process)|go:"GO:0042802"(identical protein binding)|go:"GO:0045454"(cell redox homeostasis)|go:"GO:0046475"(glycerophospholipid catabolic process)|go:"GO:0047184"(1-acylglycerophosphocholine O-acyltransferase activity)|go:"GO:0047499"(calcium-independent phospholipase A2 activity)|go:"GO:0048026"(positive regulation of mRNA splicing, via spliceosome)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051920"(peroxiredoxin activity)|go:"GO:0098869"(cellular oxidant detoxification)|go:"GO:0102567"|go:"GO:0102568"|reactome:R-MMU-3299685|reactome:R-MMU-6798695|interpro:IPR013766(Thioredoxin domain)|mint:O08709|interpro:IPR036249	-	chain-seq-start:60|chain-seq-end:166	-	figure legend:ST1.4 ST1.5 ST1.6|comment:DTT-eluted fraction|comment:The results in table 1.4,1.5 and 1.6 have been pooled together since they belong to the same experiment.|dataset:Rare diseases - Interactions investigated in the context of Rare genetic disease|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2020/12/04	2020/12/21	rogid:mvYK6+YgIN/WuGLBCWqsqPLfDyQ10090	rogid:3Hnse2vkowtSGEobI2LJX6WrNl410090	rigid:U806iAk/nRbo20C3P3OsFasoYLY	false	mutation:34-34	-	-	-	psi-mi:"MI:0082"(peptide massfingerprinting)	psi-mi:"MI:0082"(peptide massfingerprinting)
uniprotkb:P97493-PRO_0000034151	uniprotkb:Q61171	intact:EBI-26567598	intact:EBI-444957|uniprotkb:O88376|uniprotkb:Q60796|uniprotkb:Q9CWJ4|uniprotkb:Q9DB49|ensembl:ENSMUSP00000005292|ensembl:ENSMUSP00000105355|ensembl:ENSMUSP00000105356|ensembl:ENSMUSP00000126451	psi-mi:p97493-pro_0000034151(display_long)|uniprotkb:Thioredoxin-2(gene name synonym)|uniprotkb:Txn2(gene name)|psi-mi:Txn2(display_short)	psi-mi:prdx2_mouse(display_long)|uniprotkb:Thioredoxin-dependent peroxiredoxin 2(gene name synonym)|uniprotkb:Thioredoxin peroxidase 1(gene name synonym)|uniprotkb:Thioredoxin-dependent peroxide reductase 1(gene name synonym)|uniprotkb:Thiol-specific antioxidant protein(gene name synonym)|uniprotkb:Prdx2(gene name)|psi-mi:Prdx2(display_short)|uniprotkb:Tdpx1(gene name synonym)|uniprotkb:Tpx(gene name synonym)	psi-mi:"MI:0096"(pull down)	Chasapis et al. (2019)	pubmed:31018154|imex:IM-28571	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26500013|imex:IM-28571-23	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	intact:EBI-8354432(chain-parent)	refseq:NP_035693.3|go:"GO:0042098"(T cell proliferation)|go:"GO:0042743"(hydrogen peroxide metabolic process)|go:"GO:0042744"(hydrogen peroxide catabolic process)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0043209"(myelin sheath)|go:"GO:0043410"(positive regulation of MAPK cascade)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0045321"(leukocyte activation)|go:"GO:0045454"(cell redox homeostasis)|go:"GO:0045581"(negative regulation of T cell differentiation)|go:"GO:0048538"(thymus development)|go:"GO:0048872"(homeostasis of number of cells)|go:"GO:2001237"(negative regulation of extrinsic apoptotic signaling pathway)|go:"GO:2001240"(negative regulation of extrinsic apoptotic signaling pathway in absence of ligand)|interpro:IPR000866(Alkyl hydroperoxide reductase/ Thiol specific antioxidant/ Mal allergen)|interpro:IPR013766(Thioredoxin domain)|interpro:IPR019479|interpro:IPR024706|interpro:IPR036249|mint:Q61171|reactome:R-MMU-3299685|reactome:R-MMU-5628897|go:"GO:0034599"(cellular response to oxidative stress)|refseq:NP_001304314.1|ensembl:ENSMUSG00000005161(gene)|ensembl:ENSMUST00000005292(transcript)|ensembl:ENSMUST00000109733(transcript)|ensembl:ENSMUST00000109734(transcript)|ensembl:ENSMUST00000164807(transcript)|go:"GO:0002357"(defense response to tumor cell)|go:"GO:0002536"(respiratory burst involved in inflammatory response)|go:"GO:0004601"(peroxidase activity)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0006979"(response to oxidative stress)|go:"GO:0008379"(thioredoxin peroxidase activity)|go:"GO:0008430"(selenium binding)|go:"GO:0010310"(regulation of hydrogen peroxide metabolic process)|go:"GO:0016209"(antioxidant activity)|go:"GO:0019430"(removal of superoxide radicals)|go:"GO:0030194"(positive regulation of blood coagulation)|go:"GO:0031665"(negative regulation of lipopolysaccharide-mediated signaling pathway)|go:"GO:0032088"(negative regulation of NF-kappaB transcription factor activity)|go:"GO:0032496"(response to lipopolysaccharide)	-	chain-seq-start:60|chain-seq-end:166	-	figure legend:ST1.4 ST1.5 ST1.6|comment:DTT-eluted fraction|comment:The results in table 1.4,1.5 and 1.6 have been pooled together since they belong to the same experiment.|dataset:Rare diseases - Interactions investigated in the context of Rare genetic disease|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2020/12/04	2020/12/21	rogid:mvYK6+YgIN/WuGLBCWqsqPLfDyQ10090	rogid:P1NxwIOnv1n4sNzQWtFjy2znSbA10090	rigid:U806iAk/nRbo20C3P3OsFasoYLY	false	mutation:34-34	-	-	-	psi-mi:"MI:0082"(peptide massfingerprinting)	psi-mi:"MI:0082"(peptide massfingerprinting)
uniprotkb:P97493-PRO_0000034151	uniprotkb:P35700	intact:EBI-26567598	intact:EBI-444948|uniprotkb:Q3UBV4|uniprotkb:Q9CWI2|ensembl:ENSMUSP00000102078|ensembl:ENSMUSP00000114159	psi-mi:p97493-pro_0000034151(display_long)|uniprotkb:Thioredoxin-2(gene name synonym)|uniprotkb:Txn2(gene name)|psi-mi:Txn2(display_short)	psi-mi:prdx1_mouse(display_long)|uniprotkb:Thioredoxin-dependent peroxiredoxin 1(gene name synonym)|uniprotkb:Thioredoxin-dependent peroxide reductase 2(gene name synonym)|uniprotkb:Osteoblast-specific factor 3(gene name synonym)|uniprotkb:Macrophage 23 kDa stress protein(gene name synonym)|uniprotkb:Thioredoxin peroxidase 2(gene name synonym)|uniprotkb:Prdx1(gene name)|psi-mi:Prdx1(display_short)|uniprotkb:Msp23(gene name synonym)|uniprotkb:Paga(gene name synonym)|uniprotkb:Tdpx2(gene name synonym)	psi-mi:"MI:0096"(pull down)	Chasapis et al. (2019)	pubmed:31018154|imex:IM-28571	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26500013|imex:IM-28571-23	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	intact:EBI-8354432(chain-parent)	refseq:NP_035164.1|ensembl:ENSMUST00000135573(transcript)|go:"GO:0000302"(response to reactive oxygen species)|go:"GO:0000791"(euchromatin)|go:"GO:0004601"(peroxidase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0005782"(peroxisomal matrix)|go:"GO:0005829"(cytosol)|go:"GO:0006979"(response to oxidative stress)|go:"GO:0008283"(cell population proliferation)|go:"GO:0008379"(thioredoxin peroxidase activity)|go:"GO:0019430"(removal of superoxide radicals)|go:"GO:0020037"(heme binding)|go:"GO:0030101"(natural killer cell activation)|go:"GO:0032872"(regulation of stress-activated MAPK cascade)|go:"GO:0034101"(erythrocyte homeostasis)|go:"GO:0042267"(natural killer cell mediated cytotoxicity)|go:"GO:0042744"(hydrogen peroxide catabolic process)|go:"GO:0042802"(identical protein binding)|go:"GO:0043209"(myelin sheath)|go:"GO:0045321"(leukocyte activation)|go:"GO:0045454"(cell redox homeostasis)|go:"GO:0051920"(peroxiredoxin activity)|go:"GO:1901222"(regulation of NIK/NF-kappaB signaling)|interpro:IPR000866(Alkyl hydroperoxide reductase/ Thiol specific antioxidant/ Mal allergen)|interpro:IPR013766(Thioredoxin domain)|interpro:IPR019479|interpro:IPR024706|interpro:IPR036249|mint:P35700|reactome:R-MMU-3299685|reactome:R-MMU-5628897|ensembl:ENSMUST00000106470(transcript)|ensembl:ENSMUSG00000028691(gene)	-	chain-seq-start:60|chain-seq-end:166	-	figure legend:ST1.4 ST1.5 ST1.6|comment:DTT-eluted fraction|comment:The results in table 1.4,1.5 and 1.6 have been pooled together since they belong to the same experiment.|dataset:Rare diseases - Interactions investigated in the context of Rare genetic disease|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2020/12/04	2020/12/21	rogid:mvYK6+YgIN/WuGLBCWqsqPLfDyQ10090	rogid:xOppWev1GtpILoJ1rY+tSPoymVU10090	rigid:U806iAk/nRbo20C3P3OsFasoYLY	false	mutation:34-34	-	-	-	psi-mi:"MI:0082"(peptide massfingerprinting)	psi-mi:"MI:0082"(peptide massfingerprinting)
uniprotkb:P97493-PRO_0000034151	uniprotkb:Q9JIF9	intact:EBI-26567598	intact:EBI-26499535|ensembl:ENSMUSP00000025349|ensembl:ENSMUSP00000111160	psi-mi:p97493-pro_0000034151(display_long)|uniprotkb:Thioredoxin-2(gene name synonym)|uniprotkb:Txn2(gene name)|psi-mi:Txn2(display_short)	psi-mi:myoti_mouse(display_long)|uniprotkb:Myot(gene name)|psi-mi:Myot(display_short)|uniprotkb:Myo(gene name synonym)|uniprotkb:Ttid(gene name synonym)|uniprotkb:Myofibrillar titin-like Ig domains protein(gene name synonym)|uniprotkb:Titin immunoglobulin domain protein(gene name synonym)	psi-mi:"MI:0096"(pull down)	Chasapis et al. (2019)	pubmed:31018154|imex:IM-28571	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26500013|imex:IM-28571-23	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	intact:EBI-8354432(chain-parent)	ensembl:ENSMUSG00000024471(gene)|ensembl:ENSMUST00000025349(transcript)|ensembl:ENSMUST00000115498(transcript)|go:"GO:0003779"(actin binding)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005886"(plasma membrane)|go:"GO:0007156"(homophilic cell adhesion via plasma membrane adhesion molecules)|go:"GO:0007411"(axon guidance)|go:"GO:0030018"(Z disc)|go:"GO:0030424"(axon)|go:"GO:0042383"(sarcolemma)|go:"GO:0051393"(alpha-actinin binding)|go:"GO:0070593"(dendrite self-avoidance)|go:"GO:0098632"(cell-cell adhesion mediator activity)|interpro:IPR003598(Immunoglobulin subtype 2)|interpro:IPR003599(Immunoglobulin subtype)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR013098(Immunoglobulin I-set)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR036179|mint:Q9JIF9|refseq:NP_001028793.1|refseq:XP_006526196.1	-	chain-seq-start:60|chain-seq-end:166	-	figure legend:ST1.4 ST1.5 ST1.6|comment:DTT-eluted fraction|comment:The results in table 1.4,1.5 and 1.6 have been pooled together since they belong to the same experiment.|dataset:Rare diseases - Interactions investigated in the context of Rare genetic disease|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2020/12/04	2020/12/21	rogid:mvYK6+YgIN/WuGLBCWqsqPLfDyQ10090	rogid:wzvE/dGEFW4kNRhFpdlS18FztzQ10090	rigid:U806iAk/nRbo20C3P3OsFasoYLY	false	mutation:34-34	-	-	-	psi-mi:"MI:0082"(peptide massfingerprinting)	psi-mi:"MI:0082"(peptide massfingerprinting)
uniprotkb:P97493-PRO_0000034151	uniprotkb:P70402	intact:EBI-26567598	intact:EBI-26499512|ensembl:ENSMUSP00000042195|ensembl:ENSMUSP00000141104|uniprotkb:E9QKH7	psi-mi:p97493-pro_0000034151(display_long)|uniprotkb:Thioredoxin-2(gene name synonym)|uniprotkb:Txn2(gene name)|psi-mi:Txn2(display_short)	psi-mi:mybph_mouse(display_long)|uniprotkb:Mybph(gene name)|psi-mi:Mybph(display_short)|uniprotkb:H-protein(gene name synonym)	psi-mi:"MI:0096"(pull down)	Chasapis et al. (2019)	pubmed:31018154|imex:IM-28571	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26500013|imex:IM-28571-23	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	intact:EBI-8354432(chain-parent)	ensembl:ENSMUST00000191577(transcript)|go:"GO:0007155"(cell adhesion)|go:"GO:0032982"(myosin filament)|interpro:IPR003598(Immunoglobulin subtype 2)|interpro:IPR003599(Immunoglobulin subtype)|interpro:IPR003961(Fibronectin, type III)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR013098(Immunoglobulin I-set)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR036116|interpro:IPR036179|mint:P70402|ensembl:ENSMUSG00000042451(gene)|ensembl:ENSMUST00000038445(transcript)|refseq:NP_058029.2|refseq:XP_006529817.1|refseq:XP_017177184.1	-	chain-seq-start:60|chain-seq-end:166	-	figure legend:ST1.4 ST1.5 ST1.6|comment:DTT-eluted fraction|comment:The results in table 1.4,1.5 and 1.6 have been pooled together since they belong to the same experiment.|dataset:Rare diseases - Interactions investigated in the context of Rare genetic disease|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2020/12/04	2020/12/21	rogid:mvYK6+YgIN/WuGLBCWqsqPLfDyQ10090	rogid:AcWBXYIQQSB3O3Fq2HnsSK6EeNg10090	rigid:U806iAk/nRbo20C3P3OsFasoYLY	false	mutation:34-34	-	-	-	psi-mi:"MI:0082"(peptide massfingerprinting)	psi-mi:"MI:0082"(peptide massfingerprinting)
uniprotkb:P97493-PRO_0000034151	uniprotkb:Q5XKE0	intact:EBI-26567598	intact:EBI-26499483|ensembl:ENSMUSP00000130127|uniprotkb:Q8C109|uniprotkb:Q8K2V0	psi-mi:p97493-pro_0000034151(display_long)|uniprotkb:Thioredoxin-2(gene name synonym)|uniprotkb:Txn2(gene name)|psi-mi:Txn2(display_short)	psi-mi:mypc2_mouse(display_long)|uniprotkb:Mybpc2(gene name)|psi-mi:Mybpc2(display_short)|uniprotkb:C-protein, skeletal muscle fast isoform(gene name synonym)	psi-mi:"MI:0096"(pull down)	Chasapis et al. (2019)	pubmed:31018154|imex:IM-28571	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26500013|imex:IM-28571-23	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	intact:EBI-8354432(chain-parent)	ensembl:ENSMUSG00000038670(gene)|ensembl:ENSMUST00000165208(transcript)|go:"GO:0003779"(actin binding)|go:"GO:0005200"(structural constituent of cytoskeleton)|go:"GO:0005856"(cytoskeleton)|go:"GO:0006936"(muscle contraction)|go:"GO:0032982"(myosin filament)|interpro:IPR003598(Immunoglobulin subtype 2)|interpro:IPR003599(Immunoglobulin subtype)|interpro:IPR003961(Fibronectin, type III)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR013098(Immunoglobulin I-set)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR036116|interpro:IPR036179|interpro:IPR040849|mint:Q5XKE0|rcsb pdb:1X5Y|rcsb pdb:2DLT|reactome:R-MMU-390522|go:"GO:0007155"(cell adhesion)|refseq:NP_666301.2	-	chain-seq-start:60|chain-seq-end:166	-	figure legend:ST1.4 ST1.5 ST1.6|comment:DTT-eluted fraction|comment:The results in table 1.4,1.5 and 1.6 have been pooled together since they belong to the same experiment.|dataset:Rare diseases - Interactions investigated in the context of Rare genetic disease|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2020/12/04	2020/12/21	rogid:mvYK6+YgIN/WuGLBCWqsqPLfDyQ10090	rogid:JP3Y7dlKkyU1bMq5WH5cqoYs9g810090	rigid:U806iAk/nRbo20C3P3OsFasoYLY	false	mutation:34-34	-	-	-	psi-mi:"MI:0082"(peptide massfingerprinting)	psi-mi:"MI:0082"(peptide massfingerprinting)
uniprotkb:P97493-PRO_0000034151	uniprotkb:P97457	intact:EBI-26567598	intact:EBI-1634612|ensembl:ENSMUSP00000032910	psi-mi:p97493-pro_0000034151(display_long)|uniprotkb:Thioredoxin-2(gene name synonym)|uniprotkb:Txn2(gene name)|psi-mi:Txn2(display_short)	psi-mi:mlrs_mouse(display_long)|uniprotkb:Mylpf(gene name)|psi-mi:Mylpf(display_short)|uniprotkb:Fast skeletal myosin light chain 2(gene name synonym)|uniprotkb:MLC2F(gene name synonym)	psi-mi:"MI:0096"(pull down)	Chasapis et al. (2019)	pubmed:31018154|imex:IM-28571	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26500013|imex:IM-28571-23	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	intact:EBI-8354432(chain-parent)	refseq:NP_058034.1|ensembl:ENSMUSG00000030672(gene)|ensembl:ENSMUST00000032910(transcript)|go:"GO:0005509"(calcium ion binding)|go:"GO:0006955"(immune response)|go:"GO:0007519"(skeletal muscle tissue development)|go:"GO:0008307"(structural constituent of muscle)|go:"GO:0016459"(myosin complex)|interpro:IPR002048(Calcium-binding EF-hand)|interpro:IPR011992(EF-Hand type)|interpro:IPR018247|mint:P97457|rcsb pdb:7NEP|reactome:R-MMU-445355	-	chain-seq-start:60|chain-seq-end:166	-	figure legend:ST1.4 ST1.5 ST1.6|comment:DTT-eluted fraction|comment:The results in table 1.4,1.5 and 1.6 have been pooled together since they belong to the same experiment.|dataset:Rare diseases - Interactions investigated in the context of Rare genetic disease|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2020/12/04	2020/12/21	rogid:mvYK6+YgIN/WuGLBCWqsqPLfDyQ10090	rogid:7o5XhFupODE4Hfr/C77i4KkywmM10090	rigid:U806iAk/nRbo20C3P3OsFasoYLY	false	mutation:34-34	-	-	-	psi-mi:"MI:0082"(peptide massfingerprinting)	psi-mi:"MI:0082"(peptide massfingerprinting)
uniprotkb:P97493-PRO_0000034151	uniprotkb:Q8BK84	intact:EBI-26567598	intact:EBI-26499453|ensembl:ENSMUSP00000073534|uniprotkb:B2RW26	psi-mi:p97493-pro_0000034151(display_long)|uniprotkb:Thioredoxin-2(gene name synonym)|uniprotkb:Txn2(gene name)|psi-mi:Txn2(display_short)	psi-mi:dus29_mouse(display_long)|uniprotkb:Dusp29(gene name)|psi-mi:Dusp29(display_short)|uniprotkb:Dupd1(gene name synonym)|uniprotkb:Dusp27(gene name synonym)|uniprotkb:Dual specificity phosphatase DUPD1(gene name synonym)	psi-mi:"MI:0096"(pull down)	Chasapis et al. (2019)	pubmed:31018154|imex:IM-28571	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26500013|imex:IM-28571-23	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	intact:EBI-8354432(chain-parent)	ensembl:ENSMUST00000073870(transcript)|go:"GO:0004725"(protein tyrosine phosphatase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006470"(protein dephosphorylation)|go:"GO:0008138"(protein tyrosine/serine/threonine phosphatase activity)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033549"(MAP kinase phosphatase activity)|go:"GO:0042593"(glucose homeostasis)|go:"GO:0042692"(muscle cell differentiation)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0070373"(negative regulation of ERK1 and ERK2 cascade)|go:"GO:0106306"|go:"GO:0106307"|interpro:IPR000340(Protein-tyrosine phosphatase, dual specificity)|interpro:IPR000387(Protein-tyrosine phosphatase)|interpro:IPR016130(Protein-tyrosine phosphatase, active site)|interpro:IPR020405|ensembl:ENSMUSG00000063821(gene)|interpro:IPR020422|interpro:IPR029021|mint:Q8BK84|refseq:NP_001013848.1|refseq:XP_006519280.1	-	chain-seq-start:60|chain-seq-end:166	-	figure legend:ST1.4 ST1.5 ST1.6|comment:DTT-eluted fraction|comment:The results in table 1.4,1.5 and 1.6 have been pooled together since they belong to the same experiment.|dataset:Rare diseases - Interactions investigated in the context of Rare genetic disease|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2020/12/04	2020/12/21	rogid:mvYK6+YgIN/WuGLBCWqsqPLfDyQ10090	rogid:pRKMV0Kqe+3OCONYVB9Scsj/6zs10090	rigid:U806iAk/nRbo20C3P3OsFasoYLY	false	mutation:34-34	-	-	-	psi-mi:"MI:0082"(peptide massfingerprinting)	psi-mi:"MI:0082"(peptide massfingerprinting)
uniprotkb:P97493-PRO_0000034151	uniprotkb:Q91XE4	intact:EBI-26567598	intact:EBI-7378963|intact:MINT-1869885|uniprotkb:Q9DD17|uniprotkb:Q3UP59|ensembl:ENSMUSP00000050056|ensembl:ENSMUSP00000158093|ensembl:ENSMUSP00000158512	psi-mi:p97493-pro_0000034151(display_long)|uniprotkb:Thioredoxin-2(gene name synonym)|uniprotkb:Txn2(gene name)|psi-mi:Txn2(display_short)	psi-mi:acy3_mouse(display_long)|uniprotkb:Acy3(gene name)|psi-mi:Acy3(display_short)|uniprotkb:Aspa2(gene name synonym)|uniprotkb:Aminoacylase-3(gene name synonym)|uniprotkb:Aminoacylase III(gene name synonym)|uniprotkb:Acylase III(gene name synonym)|uniprotkb:Hepatitis C virus core-binding protein 1(gene name synonym)|uniprotkb:Aspartoacylase-2(gene name synonym)	psi-mi:"MI:0096"(pull down)	Chasapis et al. (2019)	pubmed:31018154|imex:IM-28571	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26500418|imex:IM-28571-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	intact:EBI-8354432(chain-parent)	refseq:NP_001289408.1|refseq:NP_001289409.1|refseq:NP_001289410.1|refseq:NP_001289411.1|ensembl:ENSMUSG00000024866(gene)|ensembl:ENSMUST00000054030(transcript)|ensembl:ENSMUST00000235612(transcript)|ensembl:ENSMUST00000236510(transcript)|go:"GO:0004046"(aminoacylase activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0016020"(membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0016788"(hydrolase activity, acting on ester bonds)|go:"GO:0016811"("hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides")|go:"GO:0042802"(identical protein binding)|go:"GO:0046872"(metal ion binding)|interpro:IPR007036(Succinylglutamate desuccinylase/aspartoacylase)|interpro:IPR016708(Aspartoacylase)|mint:Q91XE4|rcsb pdb:3NFZ|rcsb pdb:3NH4|rcsb pdb:3NH5|rcsb pdb:3NH8|reactome:R-MMU-5423646|dip:DIP-44060N	-	chain-seq-start:60|chain-seq-end:166	comment:mint|comment:homomint	figure legend:ST1.7|comment:acid-eluted fraction|dataset:Rare diseases - Interactions investigated in the context of Rare genetic disease|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2020/12/04	2020/12/21	rogid:mvYK6+YgIN/WuGLBCWqsqPLfDyQ10090	rogid:vaLqjkhOEE6W/DVCQblxUD7VcTI10090	rigid:OluZwU5INogvfGGIFu9oRk7nv1c	false	mutation:34-34	-	-	-	psi-mi:"MI:0082"(peptide massfingerprinting)	psi-mi:"MI:0082"(peptide massfingerprinting)
uniprotkb:P97493-PRO_0000034151	uniprotkb:P16460	intact:EBI-26567598	intact:EBI-8311897|ensembl:ENSMUSP00000099904|intact:MINT-1856903	psi-mi:p97493-pro_0000034151(display_long)|uniprotkb:Thioredoxin-2(gene name synonym)|uniprotkb:Txn2(gene name)|psi-mi:Txn2(display_short)	psi-mi:assy_mouse(display_long)|uniprotkb:Ass1(gene name)|psi-mi:Ass1(display_short)|uniprotkb:Ass(gene name synonym)|uniprotkb:Citrulline--aspartate ligase(gene name synonym)	psi-mi:"MI:0096"(pull down)	Chasapis et al. (2019)	pubmed:31018154|imex:IM-28571	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26500418|imex:IM-28571-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	intact:EBI-8354432(chain-parent)	ensembl:ENSMUSG00000076441(gene)|ensembl:ENSMUST00000102840(transcript)|go:"GO:0000050"(urea cycle)|go:"GO:0000052"(citrulline metabolic process)|go:"GO:0000053"(argininosuccinate metabolic process)|go:"GO:0001822"(kidney development)|go:"GO:0001889"(liver development)|go:"GO:0004055"(argininosuccinate synthase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005764"(lysosome)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005829"(cytosol)|go:"GO:0006526"(arginine biosynthetic process)|go:"GO:0006531"(aspartate metabolic process)|go:"GO:0006953"(acute-phase response)|go:"GO:0007494"(midgut development)|go:"GO:0007568"(aging)|go:"GO:0007584"(response to nutrient)|go:"GO:0007623"(circadian rhythm)|go:"GO:0010043"(response to zinc ion)|go:"GO:0010046"(response to mycotoxin)|go:"GO:0015643"(toxic substance binding)|go:"GO:0016597"(amino acid binding)|go:"GO:0032355"(response to estradiol)|go:"GO:0042493"|go:"GO:0042802"(identical protein binding)|go:"GO:0043005"(neuron projection)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043204"(perikaryon)|go:"GO:0043209"(myelin sheath)|go:"GO:0045429"(positive regulation of nitric oxide biosynthetic process)|go:"GO:0051384"(response to glucocorticoid)|go:"GO:0060416"(response to growth hormone)|go:"GO:0060539"(diaphragm development)|go:"GO:0070852"(cell body fiber)|go:"GO:0071222"(cellular response to lipopolysaccharide)|go:"GO:0071242"(cellular response to ammonium ion)|go:"GO:0071320"(cellular response to cAMP)|go:"GO:0071346"(cellular response to interferon-gamma)|go:"GO:0071356"(cellular response to tumor necrosis factor)|go:"GO:0071377"(cellular response to glucagon stimulus)|go:"GO:0071400"(cellular response to oleic acid)|go:"GO:0071418"(cellular response to amine stimulus)|go:"GO:0071499"(cellular response to laminar fluid shear stress)|go:"GO:0071549"(cellular response to dexamethasone stimulus)|go:"GO:1903038"(negative regulation of leukocyte cell-cell adhesion)|interpro:IPR001518(Argininosuccinate synthase)|interpro:IPR014729(Rossmann-like alpha/beta/alpha sandwich fold)|interpro:IPR018223|interpro:IPR023434|interpro:IPR024074|mint:P16460|reactome:R-MMU-70635|go:"GO:0071230"(cellular response to amino acid stimulus)|refseq:NP_031520.1	-	chain-seq-start:60|chain-seq-end:166	comment:mint	figure legend:ST1.7|comment:acid-eluted fraction|dataset:Rare diseases - Interactions investigated in the context of Rare genetic disease|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2020/12/04	2020/12/21	rogid:mvYK6+YgIN/WuGLBCWqsqPLfDyQ10090	rogid:ZFoIkgXjhjFrOtq5spUUqnMdaHM10090	rigid:OluZwU5INogvfGGIFu9oRk7nv1c	false	mutation:34-34	-	-	-	psi-mi:"MI:0082"(peptide massfingerprinting)	psi-mi:"MI:0082"(peptide massfingerprinting)
uniprotkb:P97493-PRO_0000034151	uniprotkb:Q9QZD9	intact:EBI-26567598	intact:EBI-7466616|intact:MINT-1869798|ensembl:ENSMUSP00000099653	psi-mi:p97493-pro_0000034151(display_long)|uniprotkb:Thioredoxin-2(gene name synonym)|uniprotkb:Txn2(gene name)|psi-mi:Txn2(display_short)	psi-mi:eif3i_mouse(display_long)|uniprotkb:Eif3i(gene name)|psi-mi:Eif3i(display_short)|uniprotkb:Trip1(gene name synonym)|uniprotkb:Eif3s2(gene name synonym)|uniprotkb:Eukaryotic translation initiation factor 3 subunit 2(gene name synonym)|uniprotkb:eIF-3-beta(gene name synonym)|uniprotkb:eIF3 p36(gene name synonym)|uniprotkb:TGF-beta receptor-interacting protein 1(gene name synonym)	psi-mi:"MI:0096"(pull down)	Chasapis et al. (2019)	pubmed:31018154|imex:IM-28571	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26500418|imex:IM-28571-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	intact:EBI-8354432(chain-parent)	refseq:NP_061269.1|ensembl:ENSMUSG00000028798(gene)|ensembl:ENSMUST00000102593(transcript)|go:"GO:0001732"(formation of cytoplasmic translation initiation complex)|go:"GO:0002183"(cytoplasmic translational initiation)|go:"GO:0003723"(RNA binding)|go:"GO:0003743"(translation initiation factor activity)|go:"GO:0005852"(eukaryotic translation initiation factor 3 complex)|go:"GO:0006413"(translational initiation)|go:"GO:0016282"(eukaryotic 43S preinitiation complex)|go:"GO:0019899"(enzyme binding)|go:"GO:0033290"(eukaryotic 48S preinitiation complex)|go:"GO:0071541"(eukaryotic translation initiation factor 3 complex, eIF3m)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019775|interpro:IPR027525|interpro:IPR036322|mint:Q9QZD9|reactome:R-MMU-156827|reactome:R-MMU-72649|reactome:R-MMU-72689|reactome:R-MMU-72695|reactome:R-MMU-72702|reactome:R-MMU-72706	-	chain-seq-start:60|chain-seq-end:166	function:Binds to the 40S ribosome and promotes the binding of methionyl-tRNAi and mRNA|comment:mint	figure legend:ST1.7|comment:acid-eluted fraction|dataset:Rare diseases - Interactions investigated in the context of Rare genetic disease|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2020/12/04	2020/12/21	rogid:mvYK6+YgIN/WuGLBCWqsqPLfDyQ10090	rogid:R7AzLvRTsjnmue48odsUwRAUIsM10090	rigid:OluZwU5INogvfGGIFu9oRk7nv1c	false	mutation:34-34	-	-	-	psi-mi:"MI:0082"(peptide massfingerprinting)	psi-mi:"MI:0082"(peptide massfingerprinting)
uniprotkb:P97493-PRO_0000034151	uniprotkb:O08553	intact:EBI-26567598	intact:EBI-446064|uniprotkb:Q6P5D0|ensembl:ENSMUSP00000022629	psi-mi:p97493-pro_0000034151(display_long)|uniprotkb:Thioredoxin-2(gene name synonym)|uniprotkb:Txn2(gene name)|psi-mi:Txn2(display_short)	psi-mi:dpyl2_mouse(display_long)|uniprotkb:Unc-33-like phosphoprotein 2(gene name synonym)|uniprotkb:Dpysl2(gene name)|psi-mi:Dpysl2(display_short)|uniprotkb:Crmp2(gene name synonym)|uniprotkb:Ulip2(gene name synonym)	psi-mi:"MI:0096"(pull down)	Chasapis et al. (2019)	pubmed:31018154|imex:IM-28571	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26500418|imex:IM-28571-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	intact:EBI-8354432(chain-parent)	refseq:NP_034085.2|ensembl:ENSMUSG00000022048(gene)|ensembl:ENSMUST00000022629(transcript)|go:"GO:0001975"(response to amphetamine)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005886"(plasma membrane)|go:"GO:0006897"(endocytosis)|go:"GO:0007010"(cytoskeleton organization)|go:"GO:0007411"(axon guidance)|go:"GO:0008017"(microtubule binding)|go:"GO:0010975"(regulation of neuron projection development)|go:"GO:0014049"(positive regulation of glutamate secretion)|go:"GO:0016810"("hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds")|go:"GO:0019901"(protein kinase binding)|go:"GO:0021510"(spinal cord development)|go:"GO:0021772"(olfactory bulb development)|go:"GO:0030424"(axon)|go:"GO:0030425"(dendrite)|go:"GO:0030426"(growth cone)|go:"GO:0030516"(regulation of axon extension)|go:"GO:0032991"(protein-containing complex)|go:"GO:0042220"(response to cocaine)|go:"GO:0042493"|go:"GO:0042802"(identical protein binding)|go:"GO:0043005"(neuron projection)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043195"(terminal bouton)|go:"GO:0043209"(myelin sheath)|go:"GO:0045664"(regulation of neuron differentiation)|go:"GO:0048489"(synaptic vesicle transport)|go:"GO:0098793"(presynapse)|interpro:IPR006680(Amidohydrolase 1)|interpro:IPR011059(Metal-dependent hydrolase, composite)|interpro:IPR011778(D-hydantoinase)|interpro:IPR030615|interpro:IPR032466|mint:O08553|rcsb pdb:5UQC|reactome:R-MMU-399956|reactome:R-MMU-437239	-	chain-seq-start:60|chain-seq-end:166	-	figure legend:ST1.7|comment:acid-eluted fraction|dataset:Rare diseases - Interactions investigated in the context of Rare genetic disease|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2020/12/04	2020/12/21	rogid:mvYK6+YgIN/WuGLBCWqsqPLfDyQ10090	rogid:97yc8TNEPMcGtGNRLvl+KV+DYr010090	rigid:OluZwU5INogvfGGIFu9oRk7nv1c	false	mutation:34-34	-	-	-	psi-mi:"MI:0082"(peptide massfingerprinting)	psi-mi:"MI:0082"(peptide massfingerprinting)
uniprotkb:P97493-PRO_0000034151	uniprotkb:P56389	intact:EBI-26567598	intact:EBI-309606|uniprotkb:Q9D7V3|ensembl:ENSMUSP00000030535	psi-mi:p97493-pro_0000034151(display_long)|uniprotkb:Thioredoxin-2(gene name synonym)|uniprotkb:Txn2(gene name)|psi-mi:Txn2(display_short)	psi-mi:cdd_mouse(display_long)|uniprotkb:Cda(gene name)|psi-mi:Cda(display_short)|uniprotkb:Cdd(gene name synonym)|uniprotkb:Cytidine aminohydrolase(gene name synonym)	psi-mi:"MI:0096"(pull down)	Chasapis et al. (2019)	pubmed:31018154|imex:IM-28571	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26500418|imex:IM-28571-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	intact:EBI-8354432(chain-parent)	refseq:NP_082452.1|ensembl:ENSMUSG00000028755(gene)|ensembl:ENSMUST00000030535(transcript)|go:"GO:0001882"(nucleoside binding)|go:"GO:0004126"(cytidine deaminase activity)|go:"GO:0005829"(cytosol)|go:"GO:0006248"(CMP catabolic process)|go:"GO:0006249"(dCMP catabolic process)|go:"GO:0008270"(zinc ion binding)|go:"GO:0009972"(cytidine deamination)|go:"GO:0019239"(deaminase activity)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0045980"(negative regulation of nucleotide metabolic process)|go:"GO:0047844"(deoxycytidine deaminase activity)|interpro:IPR002125(CMP/dCMP deaminase, zinc-binding)|interpro:IPR006262(Cytidine deaminase, homotetrameric)|interpro:IPR016192(APOBEC/CMP deaminase, zinc-binding)|interpro:IPR016193(Cytidine deaminase-like)|mint:P56389|rcsb pdb:1ZAB|rcsb pdb:2FR5|rcsb pdb:2FR6|reactome:R-MMU-6798695|reactome:R-MMU-73614	-	chain-seq-start:60|chain-seq-end:166	-	figure legend:ST1.7|comment:acid-eluted fraction|dataset:Rare diseases - Interactions investigated in the context of Rare genetic disease|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2020/12/04	2020/12/21	rogid:mvYK6+YgIN/WuGLBCWqsqPLfDyQ10090	rogid:dfGIMihZD9zI7FQJDq6Xc1E2Y6U10090	rigid:OluZwU5INogvfGGIFu9oRk7nv1c	false	mutation:34-34	-	-	-	psi-mi:"MI:0082"(peptide massfingerprinting)	psi-mi:"MI:0082"(peptide massfingerprinting)
uniprotkb:P97493-PRO_0000034151	uniprotkb:P56480	intact:EBI-26567598	intact:EBI-299482|ensembl:ENSMUSP00000026459|uniprotkb:Q0QEP4|uniprotkb:Q3TFD7|uniprotkb:Q3TIP9|uniprotkb:Q3TK44|uniprotkb:Q3TWD5|uniprotkb:Q3TX28|uniprotkb:Q3U6U4|uniprotkb:Q3U774|uniprotkb:Q3UB69|uniprotkb:Q3UF69|uniprotkb:Q8CI65|uniprotkb:Q8VEJ5|uniprotkb:Q9CTI7|uniprotkb:Q9CWX7	psi-mi:p97493-pro_0000034151(display_long)|uniprotkb:Thioredoxin-2(gene name synonym)|uniprotkb:Txn2(gene name)|psi-mi:Txn2(display_short)	psi-mi:atpb_mouse(display_long)|uniprotkb:Atp5f1b(gene name)|psi-mi:Atp5f1b(display_short)|uniprotkb:ATP synthase F1 subunit beta(gene name synonym)|uniprotkb:Atp5b(gene name synonym)	psi-mi:"MI:0096"(pull down)	Chasapis et al. (2019)	pubmed:31018154|imex:IM-28571	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26500418|imex:IM-28571-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	intact:EBI-8354432(chain-parent)	interpro:IPR024034|interpro:IPR027417|interpro:IPR036121|mint:P56480|reactome:R-MMU-1268020|reactome:R-MMU-163210|reactome:R-MMU-8949613|interpro:IPR020003|ensembl:ENSMUSG00000025393(gene)|ensembl:ENSMUST00000026459(transcript)|go:"GO:0000275"("mitochondrial proton-transporting ATP synthase complex, catalytic sector F(1)")|go:"GO:0001525"(angiogenesis)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005753"(mitochondrial proton-transporting ATP synthase complex)|go:"GO:0005886"(plasma membrane)|go:"GO:0006629"(lipid metabolic process)|go:"GO:0006754"(ATP biosynthetic process)|go:"GO:0006898"(receptor-mediated endocytosis)|go:"GO:0006933"(negative regulation of cell adhesion involved in substrate-bound cell migration)|go:"GO:0009986"(cell surface)|go:"GO:0016020"(membrane)|go:"GO:0030228"(lipoprotein particle receptor activity)|go:"GO:0031966"(mitochondrial membrane)|go:"GO:0042288"(MHC class I protein binding)|go:"GO:0042645"(mitochondrial nucleoid)|go:"GO:0042776"(mitochondrial ATP synthesis coupled proton transport)|go:"GO:0043209"(myelin sheath)|go:"GO:0043531"(ADP binding)|go:"GO:0043532"(angiostatin binding)|go:"GO:0043536"(positive regulation of blood vessel endothelial cell migration)|go:"GO:0045121"(membrane raft)|go:"GO:0045259"(proton-transporting ATP synthase complex)|go:"GO:0045261"("proton-transporting ATP synthase complex, catalytic core F(1)")|go:"GO:0046034"(ATP metabolic process)|go:"GO:0046933"(proton-transporting ATP synthase activity, rotational mechanism)|go:"GO:0046961"(proton-transporting ATPase activity, rotational mechanism)|go:"GO:0051453"(regulation of intracellular pH)|go:"GO:0098761"(cellular response to interleukin-7)|go:"GO:1902600"(proton transmembrane transport)|interpro:IPR000194(ATPase, F1/V1/A1 complex, alpha/beta subunit, nucleotide-binding)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR004100(ATPase, F1/V1/A1 complex, alpha/beta subunit, N-terminal)|interpro:IPR005722(ATPase, F1 complex, beta subunit)|go:"GO:0005524"(ATP binding)|refseq:NP_058054.2	-	chain-seq-start:60|chain-seq-end:166	-	figure legend:ST1.7|comment:acid-eluted fraction|dataset:Rare diseases - Interactions investigated in the context of Rare genetic disease|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2020/12/04	2020/12/21	rogid:mvYK6+YgIN/WuGLBCWqsqPLfDyQ10090	rogid:ihjn7GQ1ZSBfGcfwEAYSiCIuq+410090	rigid:OluZwU5INogvfGGIFu9oRk7nv1c	false	mutation:34-34	-	-	-	psi-mi:"MI:0082"(peptide massfingerprinting)	psi-mi:"MI:0082"(peptide massfingerprinting)
uniprotkb:P97493-PRO_0000034151	uniprotkb:P57780	intact:EBI-26567598	intact:EBI-445071|ensembl:ENSMUSP00000066068	psi-mi:p97493-pro_0000034151(display_long)|uniprotkb:Thioredoxin-2(gene name synonym)|uniprotkb:Txn2(gene name)|psi-mi:Txn2(display_short)	psi-mi:actn4_mouse(display_long)|uniprotkb:Non-muscle alpha-actinin 4(gene name synonym)|uniprotkb:Actn4(gene name)|psi-mi:Actn4(display_short)	psi-mi:"MI:0096"(pull down)	Chasapis et al. (2019)	pubmed:31018154|imex:IM-28571	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26500418|imex:IM-28571-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	intact:EBI-8354432(chain-parent)	refseq:NP_068695.1|go:"GO:1903506"(regulation of nucleic acid-templated transcription)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR001589(Actinin-type, actin-binding, conserved site)|interpro:IPR001715(Calponin-like actin-binding)|interpro:IPR002017(Spectrin repeat)|interpro:IPR002048(Calcium-binding EF-hand)|interpro:IPR011992(EF-Hand type)|interpro:IPR014837(EF-hand, Ca insensitive)|interpro:IPR018159|interpro:IPR018247|interpro:IPR036872|mint:P57780|reactome:R-MMU-114608|ensembl:ENSMUSG00000054808(gene)|ensembl:ENSMUST00000068045(transcript)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0001725"(stress fiber)|go:"GO:0001882"(nucleoside binding)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005911"(cell-cell junction)|go:"GO:0015031"(protein transport)|go:"GO:0016604"(nuclear body)|go:"GO:0016922"(nuclear receptor binding)|go:"GO:0030018"(Z disc)|go:"GO:0030050"(vesicle transport along actin filament)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0030374"(nuclear receptor coactivator activity)|go:"GO:0030863"(cortical cytoskeleton)|go:"GO:0031143"(pseudopodium)|go:"GO:0035357"(peroxisome proliferator activated receptor signaling pathway)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0031490"(chromatin DNA binding)|go:"GO:0042974"(retinoic acid receptor binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0033209"(tumor necrosis factor-mediated signaling pathway)|go:"GO:0043005"(neuron projection)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0047485"(protein N-terminus binding)|go:"GO:0048384"(retinoic acid receptor signaling pathway)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0048549"(positive regulation of pinocytosis)|go:"GO:0051015"(actin filament binding)|go:"GO:0051017"(actin filament bundle assembly)|go:"GO:0051271"(negative regulation of cellular component movement)|go:"GO:0051272"(positive regulation of cellular component movement)|go:"GO:0070830"(bicellular tight junction assembly)|go:"GO:1900025"(negative regulation of substrate adhesion-dependent cell spreading)|go:"GO:1901224"(positive regulation of NIK/NF-kappaB signaling)|go:"GO:1902396"(protein localization to bicellular tight junction)	-	chain-seq-start:60|chain-seq-end:166	-	figure legend:ST1.7|comment:acid-eluted fraction|dataset:Rare diseases - Interactions investigated in the context of Rare genetic disease|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2020/12/04	2020/12/21	rogid:mvYK6+YgIN/WuGLBCWqsqPLfDyQ10090	rogid:IeHeXy0Cx5E6ivN3b8IxESBlhJI10090	rigid:OluZwU5INogvfGGIFu9oRk7nv1c	false	mutation:34-34	-	-	-	psi-mi:"MI:0082"(peptide massfingerprinting)	psi-mi:"MI:0082"(peptide massfingerprinting)
uniprotkb:P97493-PRO_0000034151	uniprotkb:P47738	intact:EBI-26567598	intact:EBI-2308120|ensembl:ENSMUSP00000031411	psi-mi:p97493-pro_0000034151(display_long)|uniprotkb:Thioredoxin-2(gene name synonym)|uniprotkb:Txn2(gene name)|psi-mi:Txn2(display_short)	psi-mi:aldh2_mouse(display_long)|uniprotkb:Aldh2(gene name)|psi-mi:Aldh2(display_short)|uniprotkb:Ahd-1(gene name synonym)|uniprotkb:Ahd1(gene name synonym)|uniprotkb:ALDH class 2(gene name synonym)|uniprotkb:AHD-M1(gene name synonym)|uniprotkb:ALDHI(gene name synonym)|uniprotkb:ALDH-E2(gene name synonym)	psi-mi:"MI:0096"(pull down)	Chasapis et al. (2019)	pubmed:31018154|imex:IM-28571	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26500418|imex:IM-28571-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	intact:EBI-8354432(chain-parent)	refseq:NP_033786.1|ensembl:ENSMUSG00000029455(gene)|ensembl:ENSMUST00000031411(transcript)|go:"GO:0004029"("aldehyde dehydrogenase (NAD+) activity")|go:"GO:0005739"(mitochondrion)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0006068"(ethanol catabolic process)|go:"GO:0006117"(acetaldehyde metabolic process)|go:"GO:0008631"(intrinsic apoptotic signaling pathway in response to oxidative stress)|go:"GO:0014070"(response to organic cyclic compound)|go:"GO:0042802"(identical protein binding)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043878"("glyceraldehyde-3-phosphate dehydrogenase (NAD+) (non-phosphorylating) activity")|go:"GO:0048149"(behavioral response to ethanol)|go:"GO:0050727"(regulation of inflammatory response)|go:"GO:0051287"(NAD binding)|go:"GO:0070404"(NADH binding)|go:"GO:0110095"(cellular detoxification of aldehyde)|go:"GO:2000377"(regulation of reactive oxygen species metabolic process)|interpro:IPR015590(Aldehyde dehydrogenase)|interpro:IPR016160(Aldehyde dehydrogenase, conserved site)|interpro:IPR016161(Aldehyde/histidinol dehydrogenase)|interpro:IPR016162(Aldehyde dehydrogenase, N-terminal)|interpro:IPR016163(Aldehyde dehydrogenase, C-terminal)|interpro:IPR029510|mint:P47738|reactome:R-MMU-380612|reactome:R-MMU-71384	-	chain-seq-start:60|chain-seq-end:166	-	figure legend:ST1.7|comment:acid-eluted fraction|dataset:Rare diseases - Interactions investigated in the context of Rare genetic disease|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2020/12/04	2020/12/21	rogid:mvYK6+YgIN/WuGLBCWqsqPLfDyQ10090	rogid:C4L2qigIlQeaZH4RsNocJovkPMw10090	rigid:OluZwU5INogvfGGIFu9oRk7nv1c	false	mutation:34-34	-	-	-	psi-mi:"MI:0082"(peptide massfingerprinting)	psi-mi:"MI:0082"(peptide massfingerprinting)
uniprotkb:P97493-PRO_0000034151	uniprotkb:P62814	intact:EBI-26567598	intact:EBI-772655|uniprotkb:Q3U9Z0|uniprotkb:Q3UAW7|uniprotkb:Q3TG74|uniprotkb:Q3U7C8|uniprotkb:Q3TL62|uniprotkb:Q3TVK6|uniprotkb:Q3TWR0|uniprotkb:Q3U791|uniprotkb:O09045|uniprotkb:P50517|ensembl:ENSMUSP00000006435	psi-mi:p97493-pro_0000034151(display_long)|uniprotkb:Thioredoxin-2(gene name synonym)|uniprotkb:Txn2(gene name)|psi-mi:Txn2(display_short)	psi-mi:vatb2_mouse(display_long)|uniprotkb:Vacuolar proton pump subunit B 2(gene name synonym)|uniprotkb:Endomembrane proton pump 58 kDa subunit(gene name synonym)|uniprotkb:Atp6v1b2(gene name)|psi-mi:Atp6v1b2(display_short)|uniprotkb:Atp6b2(gene name synonym)|uniprotkb:Vat2(gene name synonym)	psi-mi:"MI:0096"(pull down)	Chasapis et al. (2019)	pubmed:31018154|imex:IM-28571	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26500418|imex:IM-28571-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	intact:EBI-8354432(chain-parent)	refseq:NP_031535.2|ensembl:ENSMUSG00000006273(gene)|ensembl:ENSMUST00000006435(transcript)|go:"GO:0000221"(vacuolar proton-transporting V-type ATPase, V1 domain)|go:"GO:0001726"(ruffle)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005902"(microvillus)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0016787"(hydrolase activity)|go:"GO:0042470"(melanosome)|go:"GO:0043209"(myelin sheath)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0046034"(ATP metabolic process)|go:"GO:1902600"(proton transmembrane transport)|interpro:IPR000194(ATPase, F1/V1/A1 complex, alpha/beta subunit, nucleotide-binding)|interpro:IPR004100(ATPase, F1/V1/A1 complex, alpha/beta subunit, N-terminal)|interpro:IPR005723(ATPase, V1 complex, subunit B)|interpro:IPR020003|interpro:IPR022879|interpro:IPR027417|mint:P62814|reactome:R-MMU-1222556|reactome:R-MMU-77387|reactome:R-MMU-917977|reactome:R-MMU-9639288|reactome:R-MMU-983712	-	chain-seq-start:60|chain-seq-end:166	-	figure legend:ST1.7|comment:acid-eluted fraction|dataset:Rare diseases - Interactions investigated in the context of Rare genetic disease|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2020/12/04	2020/12/21	rogid:mvYK6+YgIN/WuGLBCWqsqPLfDyQ10090	rogid:cmFm/xe3iOTqmy849cfoi4XeG+A10090	rigid:OluZwU5INogvfGGIFu9oRk7nv1c	false	mutation:34-34	-	-	-	psi-mi:"MI:0082"(peptide massfingerprinting)	psi-mi:"MI:0082"(peptide massfingerprinting)
uniprotkb:P97493-PRO_0000034151	uniprotkb:P50516	intact:EBI-26567598	intact:EBI-769977|uniprotkb:Q3TKS0|uniprotkb:Q3U5W3|uniprotkb:Q3U777|uniprotkb:Q3UDZ9|uniprotkb:Q3US31|uniprotkb:Q8CHX2|ensembl:ENSMUSP00000066886|ensembl:ENSMUSP00000110314	psi-mi:p97493-pro_0000034151(display_long)|uniprotkb:Thioredoxin-2(gene name synonym)|uniprotkb:Txn2(gene name)|psi-mi:Txn2(display_short)	psi-mi:vata_mouse(display_long)|uniprotkb:Vacuolar proton pump subunit alpha(gene name synonym)|uniprotkb:V-ATPase 69 kDa subunit(gene name synonym)|uniprotkb:Atp6v1a(gene name)|psi-mi:Atp6v1a(display_short)|uniprotkb:Atp6a1(gene name synonym)|uniprotkb:Atp6a2(gene name synonym)|uniprotkb:Atp6v1a1(gene name synonym)	psi-mi:"MI:0096"(pull down)	Chasapis et al. (2019)	pubmed:31018154|imex:IM-28571	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26500418|imex:IM-28571-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	intact:EBI-8354432(chain-parent)	refseq:NP_031534.2|refseq:XP_011244111.1|refseq:XP_006521783.1|refseq:XP_006521784.1|ensembl:ENSMUSG00000052459(gene)|ensembl:ENSMUST00000063661(transcript)|ensembl:ENSMUST00000114666(transcript)|go:"GO:0000221"(vacuolar proton-transporting V-type ATPase, V1 domain)|go:"GO:0005524"(ATP binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005902"(microvillus)|go:"GO:0006879"(cellular iron ion homeostasis)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0030133"(transport vesicle)|go:"GO:0030141"(secretory granule)|go:"GO:0036295"(cellular response to increased oxygen levels)|go:"GO:0043209"(myelin sheath)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0046933"(proton-transporting ATP synthase activity, rotational mechanism)|go:"GO:0046961"(proton-transporting ATPase activity, rotational mechanism)|go:"GO:1902600"(proton transmembrane transport)|interpro:IPR000194(ATPase, F1/V1/A1 complex, alpha/beta subunit, nucleotide-binding)|interpro:IPR004100(ATPase, F1/V1/A1 complex, alpha/beta subunit, N-terminal)|interpro:IPR005725(ATPase, V1 complex, subunit A)|interpro:IPR020003|interpro:IPR022878|interpro:IPR023366|interpro:IPR024034|interpro:IPR027417|interpro:IPR031686|interpro:IPR036121|mint:P50516|reactome:R-MMU-1222556|reactome:R-MMU-77387|reactome:R-MMU-917977|reactome:R-MMU-9639288|reactome:R-MMU-983712	-	chain-seq-start:60|chain-seq-end:166	-	figure legend:ST1.7|comment:acid-eluted fraction|dataset:Rare diseases - Interactions investigated in the context of Rare genetic disease|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2020/12/04	2020/12/21	rogid:mvYK6+YgIN/WuGLBCWqsqPLfDyQ10090	rogid:E6xeAhJA1x3386eC6JZXXKgRU0Q10090	rigid:OluZwU5INogvfGGIFu9oRk7nv1c	false	mutation:34-34	-	-	-	psi-mi:"MI:0082"(peptide massfingerprinting)	psi-mi:"MI:0082"(peptide massfingerprinting)
uniprotkb:P97493-PRO_0000034151	uniprotkb:Q8K2B3	intact:EBI-26567598	intact:EBI-1219461|uniprotkb:Q0QF19|uniprotkb:Q3UH25|uniprotkb:Q3UKP7|uniprotkb:Q3V4B1|uniprotkb:Q921P5|uniprotkb:Q9Z1Z4|ensembl:ENSMUSP00000022062	psi-mi:p97493-pro_0000034151(display_long)|uniprotkb:Thioredoxin-2(gene name synonym)|uniprotkb:Txn2(gene name)|psi-mi:Txn2(display_short)	psi-mi:sdha_mouse(display_long)|uniprotkb:Sdha(gene name)|psi-mi:Sdha(display_short)|uniprotkb:Flavoprotein subunit of complex II(gene name synonym)	psi-mi:"MI:0096"(pull down)	Chasapis et al. (2019)	pubmed:31018154|imex:IM-28571	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26500418|imex:IM-28571-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	intact:EBI-8354432(chain-parent)	refseq:NP_075770.1|ensembl:ENSMUSG00000021577(gene)|ensembl:ENSMUST00000022062(transcript)|go:"GO:0000104"(succinate dehydrogenase activity)|go:"GO:0005730"(nucleolus)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005749"("mitochondrial respiratory chain complex II, succinate dehydrogenase complex (ubiquinone)")|go:"GO:0006099"(tricarboxylic acid cycle)|go:"GO:0006105"(succinate metabolic process)|go:"GO:0006121"(mitochondrial electron transport, succinate to ubiquinone)|go:"GO:0007399"(nervous system development)|go:"GO:0008177"("succinate dehydrogenase (ubiquinone) activity")|go:"GO:0009055"(electron transfer activity)|go:"GO:0022904"(respiratory electron transport chain)|go:"GO:0043209"(myelin sheath)|go:"GO:0050660"(flavin adenine dinucleotide binding)|interpro:IPR003952(Fumarate reductase/succinate dehydrogenase, FAD-binding site)|interpro:IPR003953(Fumarate reductase/succinate dehydrogenase flavoprotein, N-terminal)|interpro:IPR011281(Succinate dehydrogenase, flavoprotein subunit)|interpro:IPR014006(Succinate dehydrogenase or fumarate reductase, flavoprotein subunit)|interpro:IPR015939(Fumarate reductase/succinate dehydrogenase flavoprotein-like, C-terminal)|interpro:IPR027477|interpro:IPR036188|interpro:IPR037099|mint:Q8K2B3|reactome:R-MMU-71403	-	chain-seq-start:60|chain-seq-end:166	-	figure legend:ST1.7|comment:acid-eluted fraction|dataset:Rare diseases - Interactions investigated in the context of Rare genetic disease|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2020/12/04	2020/12/21	rogid:mvYK6+YgIN/WuGLBCWqsqPLfDyQ10090	rogid:DbI/pBVBwa3ezreOqH3hgGy1qkA10090	rigid:OluZwU5INogvfGGIFu9oRk7nv1c	false	mutation:34-34	-	-	-	psi-mi:"MI:0082"(peptide massfingerprinting)	psi-mi:"MI:0082"(peptide massfingerprinting)
uniprotkb:P97493-PRO_0000034151	uniprotkb:P62270	intact:EBI-26567598	intact:EBI-352460|ensembl:ENSMUSP00000008812|uniprotkb:P25232	psi-mi:p97493-pro_0000034151(display_long)|uniprotkb:Thioredoxin-2(gene name synonym)|uniprotkb:Txn2(gene name)|psi-mi:Txn2(display_short)	psi-mi:rs18_mouse(display_long)|uniprotkb:Rps18(gene name)|psi-mi:Rps18(display_short)|uniprotkb:Ke-3(gene name synonym)	psi-mi:"MI:0096"(pull down)	Chasapis et al. (2019)	pubmed:31018154|imex:IM-28571	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26500418|imex:IM-28571-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	intact:EBI-8354432(chain-parent)	refseq:NP_035426.1|ensembl:ENSMUSG00000008668(gene)|ensembl:ENSMUST00000008812(transcript)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0006412"(translation)|go:"GO:0014069"(postsynaptic density)|go:"GO:0015935"(small ribosomal subunit)|go:"GO:0019843"(rRNA binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0022626"(cytosolic ribosome)|go:"GO:0022627"(cytosolic small ribosomal subunit)|go:"GO:0045202"(synapse)|interpro:IPR001892(Ribosomal protein S13)|interpro:IPR010979(Ribosomal protein S13-like, H2TH)|interpro:IPR018269|interpro:IPR027437|mint:P62270|reactome:R-MMU-156827|reactome:R-MMU-1799339|reactome:R-MMU-6791226|reactome:R-MMU-72649|reactome:R-MMU-72689|reactome:R-MMU-72695|reactome:R-MMU-72702|reactome:R-MMU-72706|reactome:R-MMU-975956|reactome:R-MMU-975957	-	chain-seq-start:60|chain-seq-end:166	-	figure legend:ST1.7|comment:acid-eluted fraction|dataset:Rare diseases - Interactions investigated in the context of Rare genetic disease|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2020/12/04	2020/12/21	rogid:mvYK6+YgIN/WuGLBCWqsqPLfDyQ10090	rogid:yOHgKM/BuvgGdqp1OEVPeuiABg810090	rigid:OluZwU5INogvfGGIFu9oRk7nv1c	false	mutation:34-34	-	-	-	psi-mi:"MI:0082"(peptide massfingerprinting)	psi-mi:"MI:0082"(peptide massfingerprinting)
uniprotkb:P97493-PRO_0000034151	uniprotkb:P16546	intact:EBI-26567598	intact:EBI-911063|uniprotkb:A3KGU6|uniprotkb:Q8K380|uniprotkb:Q9CT05|uniprotkb:A3KGU8|ensembl:ENSMUSP00000092697	psi-mi:p97493-pro_0000034151(display_long)|uniprotkb:Thioredoxin-2(gene name synonym)|uniprotkb:Txn2(gene name)|psi-mi:Txn2(display_short)	psi-mi:sptn1_mouse(display_long)|uniprotkb:Alpha-II spectrin(gene name synonym)|uniprotkb:Fodrin alpha chain(gene name synonym)|uniprotkb:Sptan1(gene name)|psi-mi:Sptan1(display_short)|uniprotkb:Spna2(gene name synonym)|uniprotkb:Spta2(gene name synonym)	psi-mi:"MI:0096"(pull down)	Chasapis et al. (2019)	pubmed:31018154|imex:IM-28571	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26500418|imex:IM-28571-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	intact:EBI-8354432(chain-parent)	dip:DIP-37712N|ensembl:ENSMUSG00000057738(gene)|ensembl:ENSMUST00000095083(transcript)|go:"GO:0003779"(actin binding)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005916"(fascia adherens)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0016020"(membrane)|go:"GO:0016328"(lateral plasma membrane)|go:"GO:0019905"(syntaxin binding)|go:"GO:0030018"(Z disc)|go:"GO:0030507"(spectrin binding)|go:"GO:0030863"(cortical cytoskeleton)|go:"GO:0031532"(actin cytoskeleton reorganization)|go:"GO:0032437"(cuticular plate)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033270"(paranode region of axon)|go:"GO:0043209"(myelin sheath)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0051693"(actin filament capping)|interpro:IPR001452(Src homology-3)|interpro:IPR002017(Spectrin repeat)|interpro:IPR002048(Calcium-binding EF-hand)|interpro:IPR011992(EF-Hand type)|interpro:IPR014837(EF-hand, Ca insensitive)|interpro:IPR018159|interpro:IPR018247|interpro:IPR035825|interpro:IPR036028|mint:P16546|reactome:R-MMU-264870|reactome:R-MMU-375165|reactome:R-MMU-445095|reactome:R-MMU-5673001|reactome:R-MMU-6798695|reactome:R-MMU-6807878|reactome:R-MMU-9013420|reactome:R-MMU-9013424	-	chain-seq-start:60|chain-seq-end:166	-	figure legend:ST1.7|comment:acid-eluted fraction|dataset:Rare diseases - Interactions investigated in the context of Rare genetic disease|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2020/12/04	2020/12/21	rogid:mvYK6+YgIN/WuGLBCWqsqPLfDyQ10090	rogid:UVB6Kv+PBlqDH3OLoGjxm5oYVPQ10090	rigid:OluZwU5INogvfGGIFu9oRk7nv1c	false	mutation:34-34	-	-	-	psi-mi:"MI:0082"(peptide massfingerprinting)	psi-mi:"MI:0082"(peptide massfingerprinting)
uniprotkb:P97493-PRO_0000034151	uniprotkb:P42208	intact:EBI-26567598	intact:EBI-772099|uniprotkb:Q3U9Y5|uniprotkb:B2RRZ2|ensembl:ENSMUSP00000027495|ensembl:ENSMUSP00000132850|ensembl:ENSMUSP00000136366	psi-mi:p97493-pro_0000034151(display_long)|uniprotkb:Thioredoxin-2(gene name synonym)|uniprotkb:Txn2(gene name)|psi-mi:Txn2(display_short)	psi-mi:sept2_mouse(display_long)|uniprotkb:Sept2(gene name synonym)|uniprotkb:Septin2(gene name)|psi-mi:Septin2(display_short)|uniprotkb:Nedd5(gene name synonym)|uniprotkb:Neural precursor cell expressed developmentally down-regulated protein 5(gene name synonym)	psi-mi:"MI:0096"(pull down)	Chasapis et al. (2019)	pubmed:31018154|imex:IM-28571	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26500418|imex:IM-28571-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	intact:EBI-8354432(chain-parent)	refseq:NP_001153189.1|refseq:NP_001153190.1|refseq:NP_001153191.1|refseq:NP_035021.1|refseq:XP_006529304.1|refseq:XP_006529305.1|dip:DIP-32438N|ensembl:ENSMUSG00000026276(gene)|ensembl:ENSMUSG00000116048(gene)|ensembl:ENSMUST00000027495(transcript)|ensembl:ENSMUST00000168776(transcript)|ensembl:ENSMUST00000179353(transcript)|go:"GO:0000145"(exocyst)|go:"GO:0000776"(kinetochore)|go:"GO:0002036"(regulation of L-glutamate import across plasma membrane)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005826"(actomyosin contractile ring)|go:"GO:0005876"(spindle microtubule)|go:"GO:0005886"(plasma membrane)|go:"GO:0005930"(axoneme)|go:"GO:0005938"(cell cortex)|go:"GO:0005940"(septin ring)|go:"GO:0007224"(smoothened signaling pathway)|go:"GO:0007283"(spermatogenesis)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0009986"(cell surface)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0017157"(regulation of exocytosis)|go:"GO:0030234"(enzyme regulator activity)|go:"GO:0030496"(midbody)|go:"GO:0031105"(septin complex)|go:"GO:0031175"(neuron projection development)|go:"GO:0032153"(cell division site)|go:"GO:0032154"(cleavage furrow)|go:"GO:0032391"(photoreceptor connecting cilium)|go:"GO:0032880"(regulation of protein localization)|go:"GO:0034613"(cellular protein localization)|go:"GO:0035869"(ciliary transition zone)|go:"GO:0042802"(identical protein binding)|go:"GO:0042995"(cell projection)|go:"GO:0043209"(myelin sheath)|go:"GO:0045171"(intercellular bridge)|go:"GO:0045202"(synapse)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051258"(protein polymerization)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0060170"(ciliary membrane)|go:"GO:0060271"(cilium assembly)|go:"GO:0061640"(cytoskeleton-dependent cytokinesis)|go:"GO:0097227"(sperm annulus)|go:"GO:0097730"(non-motile cilium)|interpro:IPR008113(Septin 2)|interpro:IPR016491(Septin)|interpro:IPR027417|interpro:IPR030379|rcsb pdb:3FTQ|reactome:R-MMU-5620912|mint:P42208	-	chain-seq-start:60|chain-seq-end:166	-	figure legend:ST1.7|comment:acid-eluted fraction|dataset:Rare diseases - Interactions investigated in the context of Rare genetic disease|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2020/12/04	2020/12/21	rogid:mvYK6+YgIN/WuGLBCWqsqPLfDyQ10090	rogid:vk7UVRzpfbNxL4cxXJhd94mfQxc10090	rigid:OluZwU5INogvfGGIFu9oRk7nv1c	false	mutation:34-34	-	-	-	psi-mi:"MI:0082"(peptide massfingerprinting)	psi-mi:"MI:0082"(peptide massfingerprinting)
uniprotkb:P97493-PRO_0000034151	uniprotkb:P99029	intact:EBI-26567598	intact:EBI-2735704|uniprotkb:Q9QX45|uniprotkb:Q9QZ75|ensembl:ENSMUSP00000025904	psi-mi:p97493-pro_0000034151(display_long)|uniprotkb:Thioredoxin-2(gene name synonym)|uniprotkb:Txn2(gene name)|psi-mi:Txn2(display_short)	psi-mi:prdx5_mouse(display_long)|uniprotkb:Prdx5(gene name)|psi-mi:Prdx5(display_short)|uniprotkb:Prdx6(gene name synonym)|uniprotkb:Peroxiredoxin V(gene name synonym)|uniprotkb:Peroxisomal antioxidant enzyme(gene name synonym)|uniprotkb:PLP(gene name synonym)|uniprotkb:Thioredoxin peroxidase PMP20(gene name synonym)|uniprotkb:Antioxidant enzyme B166(gene name synonym)|uniprotkb:Liver tissue 2D-page spot 2D-0014IV(gene name synonym)|uniprotkb:Thioredoxin-dependent peroxiredoxin 5(gene name synonym)	psi-mi:"MI:0096"(pull down)	Chasapis et al. (2019)	pubmed:31018154|imex:IM-28571	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26500418|imex:IM-28571-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	intact:EBI-8354432(chain-parent)	refseq:NP_036151.1|ensembl:ENSMUSG00000024953(gene)|ensembl:ENSMUST00000025904(transcript)|go:"GO:0001016"(RNA polymerase III transcription regulatory region sequence-specific DNA binding)|go:"GO:0004601"(peroxidase activity)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005777"(peroxisome)|go:"GO:0005782"(peroxisomal matrix)|go:"GO:0005829"(cytosol)|go:"GO:0006979"(response to oxidative stress)|go:"GO:0008379"(thioredoxin peroxidase activity)|go:"GO:0016209"(antioxidant activity)|go:"GO:0016480"(negative regulation of transcription by RNA polymerase III)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0032967"(positive regulation of collagen biosynthetic process)|go:"GO:0034599"(cellular response to oxidative stress)|go:"GO:0034614"(cellular response to reactive oxygen species)|go:"GO:0042744"(hydrogen peroxide catabolic process)|go:"GO:0043027"(cysteine-type endopeptidase inhibitor activity involved in apoptotic process)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0045454"(cell redox homeostasis)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051354"(negative regulation of oxidoreductase activity)|go:"GO:0051920"(peroxiredoxin activity)|go:"GO:0060785"(regulation of apoptosis involved in tissue homeostasis)|go:"GO:0070995"(NADPH oxidation)|go:"GO:0072541"(peroxynitrite reductase activity)|go:"GO:2001057"(reactive nitrogen species metabolic process)|interpro:IPR013740(Redoxin)|interpro:IPR036249|interpro:IPR037944|mint:P99029|reactome:R-MMU-3299685|reactome:R-MMU-5628897|interpro:IPR013766(Thioredoxin domain)	-	chain-seq-start:60|chain-seq-end:166	-	figure legend:ST1.7|comment:acid-eluted fraction|dataset:Rare diseases - Interactions investigated in the context of Rare genetic disease|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2020/12/04	2020/12/21	rogid:mvYK6+YgIN/WuGLBCWqsqPLfDyQ10090	rogid:uWS2EcAdupLmsVsQ6h1AV+vRffs10090	rigid:OluZwU5INogvfGGIFu9oRk7nv1c	false	mutation:34-34	-	-	-	psi-mi:"MI:0082"(peptide massfingerprinting)	psi-mi:"MI:0082"(peptide massfingerprinting)
uniprotkb:P97493-PRO_0000034151	uniprotkb:Q61171	intact:EBI-26567598	intact:EBI-444957|uniprotkb:O88376|uniprotkb:Q60796|uniprotkb:Q9CWJ4|uniprotkb:Q9DB49|ensembl:ENSMUSP00000005292|ensembl:ENSMUSP00000105355|ensembl:ENSMUSP00000105356|ensembl:ENSMUSP00000126451	psi-mi:p97493-pro_0000034151(display_long)|uniprotkb:Thioredoxin-2(gene name synonym)|uniprotkb:Txn2(gene name)|psi-mi:Txn2(display_short)	psi-mi:prdx2_mouse(display_long)|uniprotkb:Thioredoxin-dependent peroxiredoxin 2(gene name synonym)|uniprotkb:Thioredoxin peroxidase 1(gene name synonym)|uniprotkb:Thioredoxin-dependent peroxide reductase 1(gene name synonym)|uniprotkb:Thiol-specific antioxidant protein(gene name synonym)|uniprotkb:Prdx2(gene name)|psi-mi:Prdx2(display_short)|uniprotkb:Tdpx1(gene name synonym)|uniprotkb:Tpx(gene name synonym)	psi-mi:"MI:0096"(pull down)	Chasapis et al. (2019)	pubmed:31018154|imex:IM-28571	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26500418|imex:IM-28571-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	intact:EBI-8354432(chain-parent)	refseq:NP_035693.3|go:"GO:0042098"(T cell proliferation)|go:"GO:0042743"(hydrogen peroxide metabolic process)|go:"GO:0042744"(hydrogen peroxide catabolic process)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0043209"(myelin sheath)|go:"GO:0043410"(positive regulation of MAPK cascade)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0045321"(leukocyte activation)|go:"GO:0045454"(cell redox homeostasis)|go:"GO:0045581"(negative regulation of T cell differentiation)|go:"GO:0048538"(thymus development)|go:"GO:0048872"(homeostasis of number of cells)|go:"GO:2001237"(negative regulation of extrinsic apoptotic signaling pathway)|go:"GO:2001240"(negative regulation of extrinsic apoptotic signaling pathway in absence of ligand)|interpro:IPR000866(Alkyl hydroperoxide reductase/ Thiol specific antioxidant/ Mal allergen)|interpro:IPR013766(Thioredoxin domain)|interpro:IPR019479|interpro:IPR024706|interpro:IPR036249|mint:Q61171|reactome:R-MMU-3299685|reactome:R-MMU-5628897|go:"GO:0034599"(cellular response to oxidative stress)|refseq:NP_001304314.1|ensembl:ENSMUSG00000005161(gene)|ensembl:ENSMUST00000005292(transcript)|ensembl:ENSMUST00000109733(transcript)|ensembl:ENSMUST00000109734(transcript)|ensembl:ENSMUST00000164807(transcript)|go:"GO:0002357"(defense response to tumor cell)|go:"GO:0002536"(respiratory burst involved in inflammatory response)|go:"GO:0004601"(peroxidase activity)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0006979"(response to oxidative stress)|go:"GO:0008379"(thioredoxin peroxidase activity)|go:"GO:0008430"(selenium binding)|go:"GO:0010310"(regulation of hydrogen peroxide metabolic process)|go:"GO:0016209"(antioxidant activity)|go:"GO:0019430"(removal of superoxide radicals)|go:"GO:0030194"(positive regulation of blood coagulation)|go:"GO:0031665"(negative regulation of lipopolysaccharide-mediated signaling pathway)|go:"GO:0032088"(negative regulation of NF-kappaB transcription factor activity)|go:"GO:0032496"(response to lipopolysaccharide)	-	chain-seq-start:60|chain-seq-end:166	-	figure legend:ST1.7|comment:acid-eluted fraction|dataset:Rare diseases - Interactions investigated in the context of Rare genetic disease|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2020/12/04	2020/12/21	rogid:mvYK6+YgIN/WuGLBCWqsqPLfDyQ10090	rogid:P1NxwIOnv1n4sNzQWtFjy2znSbA10090	rigid:OluZwU5INogvfGGIFu9oRk7nv1c	false	mutation:34-34	-	-	-	psi-mi:"MI:0082"(peptide massfingerprinting)	psi-mi:"MI:0082"(peptide massfingerprinting)
uniprotkb:P97493-PRO_0000034151	uniprotkb:Q91VD9	intact:EBI-26567598	intact:EBI-772739|uniprotkb:Q3UQ73|uniprotkb:Q8BM16|ensembl:ENSMUSP00000027111|ensembl:ENSMUSP00000126621	psi-mi:p97493-pro_0000034151(display_long)|uniprotkb:Thioredoxin-2(gene name synonym)|uniprotkb:Txn2(gene name)|psi-mi:Txn2(display_short)	psi-mi:ndus1_mouse(display_long)|uniprotkb:Complex I-75kD(gene name synonym)|uniprotkb:Ndufs1(gene name)|psi-mi:Ndufs1(display_short)	psi-mi:"MI:0096"(pull down)	Chasapis et al. (2019)	pubmed:31018154|imex:IM-28571	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26500418|imex:IM-28571-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	intact:EBI-8354432(chain-parent)	refseq:NP_001153510.1|refseq:NP_001153511.1|refseq:NP_001153512.1|refseq:NP_663493.2|refseq:XP_006496015.1|ensembl:ENSMUSG00000025968(gene)|ensembl:ENSMUST00000027111(transcript)|ensembl:ENSMUST00000168099(transcript)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005747"(mitochondrial respiratory chain complex I)|go:"GO:0005758"(mitochondrial intermembrane space)|go:"GO:0006120"(mitochondrial electron transport, NADH to ubiquinone)|go:"GO:0008137"("NADH dehydrogenase (ubiquinone) activity")|go:"GO:0008637"(apoptotic mitochondrial changes)|go:"GO:0009055"(electron transfer activity)|go:"GO:0032981"(mitochondrial respiratory chain complex I assembly)|go:"GO:0043209"(myelin sheath)|go:"GO:0045333"(cellular respiration)|go:"GO:0046034"(ATP metabolic process)|go:"GO:0046872"(metal ion binding)|go:"GO:0051537"(2 iron, 2 sulfur cluster binding)|go:"GO:0051539"(4 iron, 4 sulfur cluster binding)|go:"GO:0051881"(regulation of mitochondrial membrane potential)|go:"GO:0072593"(reactive oxygen species metabolic process)|interpro:IPR000283(NADH dehydrogenase 75 kDa subunit, conserved site)|interpro:IPR001041(Ferredoxin)|interpro:IPR006656(Molybdopterin oxidoreductase)|interpro:IPR006963(Molybdopterin oxidoreductase Fe4S4 region)|interpro:IPR010228(NADH-quinone oxidoreductase, chain G)|interpro:IPR015405(NADH-quinone oxidoreductase, chain G, C-terminal)|interpro:IPR019574|interpro:IPR036010|mint:Q91VD9|rcsb pdb:6G2J|rcsb pdb:6G72|rcsb pdb:6ZR2|rcsb pdb:6ZTQ|rcsb pdb:7AK5|rcsb pdb:7AK6|rcsb pdb:7B93|reactome:R-MMU-611105|reactome:R-MMU-6799198	-	chain-seq-start:60|chain-seq-end:166	-	figure legend:ST1.7|comment:acid-eluted fraction|dataset:Rare diseases - Interactions investigated in the context of Rare genetic disease|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2020/12/04	2020/12/21	rogid:mvYK6+YgIN/WuGLBCWqsqPLfDyQ10090	rogid:/akd0DjF9D063ihVFyTA0+Q0gJQ10090	rigid:OluZwU5INogvfGGIFu9oRk7nv1c	false	mutation:34-34	-	-	-	psi-mi:"MI:0082"(peptide massfingerprinting)	psi-mi:"MI:0082"(peptide massfingerprinting)
uniprotkb:P97493-PRO_0000034151	uniprotkb:Q91WD5	intact:EBI-26567598	intact:EBI-772751|uniprotkb:Q3U5Y9|uniprotkb:Q3UJX7|uniprotkb:Q99L23|uniprotkb:Q3TNA8|ensembl:ENSMUSP00000013737	psi-mi:p97493-pro_0000034151(display_long)|uniprotkb:Thioredoxin-2(gene name synonym)|uniprotkb:Txn2(gene name)|psi-mi:Txn2(display_short)	psi-mi:ndus2_mouse(display_long)|uniprotkb:NADH-ubiquinone oxidoreductase 49 kDa subunit(gene name synonym)|uniprotkb:Complex I-49kD(gene name synonym)|uniprotkb:Ndufs2(gene name)|psi-mi:Ndufs2(display_short)	psi-mi:"MI:0096"(pull down)	Chasapis et al. (2019)	pubmed:31018154|imex:IM-28571	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26500418|imex:IM-28571-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	intact:EBI-8354432(chain-parent)	refseq:NP_694704.1|ensembl:ENSMUSG00000013593(gene)|ensembl:ENSMUST00000013737(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005747"(mitochondrial respiratory chain complex I)|go:"GO:0006120"(mitochondrial electron transport, NADH to ubiquinone)|go:"GO:0006979"(response to oxidative stress)|go:"GO:0008137"("NADH dehydrogenase (ubiquinone) activity")|go:"GO:0019826"(oxygen sensor activity)|go:"GO:0022008"(neurogenesis)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032981"(mitochondrial respiratory chain complex I assembly)|go:"GO:0042063"(gliogenesis)|go:"GO:0042775"(mitochondrial ATP synthesis coupled electron transport)|go:"GO:0046872"(metal ion binding)|go:"GO:0048038"(quinone binding)|go:"GO:0051287"(NAD binding)|go:"GO:0051539"(4 iron, 4 sulfur cluster binding)|go:"GO:0061351"(neural precursor cell proliferation)|go:"GO:0071453"(cellular response to oxygen levels)|interpro:IPR001135(NADH-ubiquinone oxidoreductase, chain 49kDa)|interpro:IPR014029(NADH-ubiquinone oxidoreductase, chain 49kDa, conserved site)|interpro:IPR022885|interpro:IPR029014|mint:Q91WD5|rcsb pdb:6G2J|rcsb pdb:6G72|rcsb pdb:6ZR2|rcsb pdb:6ZTQ|rcsb pdb:7AK5|rcsb pdb:7AK6|rcsb pdb:7B93|reactome:R-MMU-611105|reactome:R-MMU-6799198	-	chain-seq-start:60|chain-seq-end:166	-	figure legend:ST1.7|comment:acid-eluted fraction|dataset:Rare diseases - Interactions investigated in the context of Rare genetic disease|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2020/12/04	2020/12/21	rogid:mvYK6+YgIN/WuGLBCWqsqPLfDyQ10090	rogid:dk8e26C1hIdTZvDnX5nE1n+juwk10090	rigid:OluZwU5INogvfGGIFu9oRk7nv1c	false	mutation:34-34	-	-	-	psi-mi:"MI:0082"(peptide massfingerprinting)	psi-mi:"MI:0082"(peptide massfingerprinting)
uniprotkb:P97493-PRO_0000034151	uniprotkb:Q8VDD5	intact:EBI-26567598	intact:EBI-400906|intact:EBI-777674|uniprotkb:Q3UHT9|uniprotkb:Q3UHU4|uniprotkb:Q6KAN6|uniprotkb:Q811I2|ensembl:ENSMUSP00000016771	psi-mi:p97493-pro_0000034151(display_long)|uniprotkb:Thioredoxin-2(gene name synonym)|uniprotkb:Txn2(gene name)|psi-mi:Txn2(display_short)	psi-mi:myh9_mouse(display_long)|uniprotkb:Myh9(gene name)|psi-mi:Myh9(display_short)|uniprotkb:Myosin heavy chain 9(gene name synonym)|uniprotkb:Myosin heavy chain, non-muscle IIa(gene name synonym)|uniprotkb:Non-muscle myosin heavy chain IIa(gene name synonym)|uniprotkb:Cellular myosin heavy chain, type A(gene name synonym)|uniprotkb:Non-muscle myosin heavy chain A(gene name synonym)	psi-mi:"MI:0096"(pull down)	Chasapis et al. (2019)	pubmed:31018154|imex:IM-28571	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26500418|imex:IM-28571-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	intact:EBI-8354432(chain-parent)	refseq:NP_071855.2|ensembl:ENSMUSG00000022443(gene)|ensembl:ENSMUST00000016771(transcript)|go:"GO:0000146"(microfilament motor activity)|go:"GO:0000212"(meiotic spindle organization)|go:"GO:0000904"(cell morphogenesis involved in differentiation)|go:"GO:0001525"(angiogenesis)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0001725"(stress fiber)|go:"GO:0001726"(ruffle)|go:"GO:0001768"(establishment of T cell polarity)|go:"GO:0001772"(immunological synapse)|go:"GO:0001778"(plasma membrane repair)|go:"GO:0001931"(uropod)|go:"GO:0003779"(actin binding)|go:"GO:0005178"(integrin binding)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005819"(spindle)|go:"GO:0005826"(actomyosin contractile ring)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005903"(brush border)|go:"GO:0005912"(adherens junction)|go:"GO:0005938"(cell cortex)|go:"GO:0006509"(membrane protein ectodomain proteolysis)|go:"GO:0006911"(phagocytosis, engulfment)|go:"GO:0007155"(cell adhesion)|go:"GO:0007520"(myoblast fusion)|go:"GO:0008180"(COP9 signalosome)|go:"GO:0008360"(regulation of cell shape)|go:"GO:0009898"(cytoplasmic side of plasma membrane)|go:"GO:0015031"(protein transport)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0016459"(myosin complex)|go:"GO:0016460"(myosin II complex)|go:"GO:0016887"(ATP hydrolysis activity)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030048"(actin filament-based movement)|go:"GO:0030220"(platelet formation)|go:"GO:0030224"(monocyte differentiation)|go:"GO:0030863"(cortical cytoskeleton)|go:"GO:0031032"(actomyosin structure organization)|go:"GO:0031252"(cell leading edge)|go:"GO:0031532"(actin cytoskeleton reorganization)|go:"GO:0031594"(neuromuscular junction)|go:"GO:0032154"(cleavage furrow)|go:"GO:0032418"(lysosome localization)|go:"GO:0032506"(cytokinetic process)|go:"GO:0032796"(uropod organization)|go:"GO:0032991"(protein-containing complex)|go:"GO:0042641"(actomyosin)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043495"(protein-membrane adaptor activity)|go:"GO:0043531"(ADP binding)|go:"GO:0043534"(blood vessel endothelial cell migration)|go:"GO:0045055"(regulated exocytosis)|go:"GO:0051015"(actin filament binding)|go:"GO:0051295"(establishment of meiotic spindle localization)|go:"GO:0060471"(cortical granule exocytosis)|go:"GO:0060473"(cortical granule)|go:"GO:0097513"(myosin II filament)|go:"GO:0098609"(cell-cell adhesion)|go:"GO:1903919"(negative regulation of actin filament severing)|go:"GO:1903923"(positive regulation of protein processing in phagocytic vesicle)|go:"GO:1905684"(regulation of plasma membrane repair)|interpro:IPR000048(IQ calmodulin-binding region)|interpro:IPR001609(Myosin head, motor region)|interpro:IPR002928(Myosin tail)|interpro:IPR004009(Myosin, N-terminal, SH3-like)|interpro:IPR008989(Myosin S1 fragment, N-terminal)|interpro:IPR027417|interpro:IPR036961|mint:Q8VDD5|reactome:R-MMU-2029482|reactome:R-MMU-5627123|dip:DIP-29546N	-	chain-seq-start:60|chain-seq-end:166	caution:This sequence has been withdrawn from Uniprot.|crc64:AAAC0E83A0A4F24A	figure legend:ST1.7|comment:acid-eluted fraction|dataset:Rare diseases - Interactions investigated in the context of Rare genetic disease|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2020/12/04	2020/12/21	rogid:mvYK6+YgIN/WuGLBCWqsqPLfDyQ10090	rogid:qYfcGuWOF9npzsKD3zXTuLeP9iE10090	rigid:OluZwU5INogvfGGIFu9oRk7nv1c	false	mutation:34-34	-	-	-	psi-mi:"MI:0082"(peptide massfingerprinting)	psi-mi:"MI:0082"(peptide massfingerprinting)
uniprotkb:P97493-PRO_0000034151	uniprotkb:Q3ULD5	intact:EBI-26567598	intact:EBI-6877475|ensembl:ENSMUSP00000022148|uniprotkb:Q3UPS6	psi-mi:p97493-pro_0000034151(display_long)|uniprotkb:Thioredoxin-2(gene name synonym)|uniprotkb:Txn2(gene name)|psi-mi:Txn2(display_short)	psi-mi:mccb_mouse(display_long)|uniprotkb:Mccc2(gene name)|psi-mi:Mccc2(display_short)|uniprotkb:3-methylcrotonyl-CoA carboxylase 2(gene name synonym)|uniprotkb:3-methylcrotonyl-CoA carboxylase non-biotin-containing subunit(gene name synonym)|uniprotkb:"3-methylcrotonyl-CoA:carbon dioxide ligase subunit beta"(gene name synonym)	psi-mi:"MI:0096"(pull down)	Chasapis et al. (2019)	pubmed:31018154|imex:IM-28571	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26500418|imex:IM-28571-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	intact:EBI-8354432(chain-parent)	ensembl:ENSMUSG00000021646(gene)|ensembl:ENSMUST00000022148(transcript)|go:"GO:0004485"(methylcrotonoyl-CoA carboxylase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005739"(mitochondrion)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0006552"(leucine catabolic process)|go:"GO:0015936"(coenzyme A metabolic process)|go:"GO:1905202"(methylcrotonoyl-CoA carboxylase complex)|interpro:IPR011762(Acetyl-coenzyme A carboxyltransferase, N-terminal)|interpro:IPR011763(Acetyl-coenzyme A carboxyltransferase, C-terminal)|interpro:IPR029045|interpro:IPR034733|mint:Q3ULD5|reactome:R-MMU-196780|reactome:R-MMU-70895|refseq:NP_084302.1	-	chain-seq-start:60|chain-seq-end:166	-	figure legend:ST1.7|comment:acid-eluted fraction|dataset:Rare diseases - Interactions investigated in the context of Rare genetic disease|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2020/12/04	2020/12/21	rogid:mvYK6+YgIN/WuGLBCWqsqPLfDyQ10090	rogid:0q4wsAWb+zqTRNjZnCPoNabUrbA10090	rigid:OluZwU5INogvfGGIFu9oRk7nv1c	false	mutation:34-34	-	-	-	psi-mi:"MI:0082"(peptide massfingerprinting)	psi-mi:"MI:0082"(peptide massfingerprinting)
uniprotkb:P97493-PRO_0000034151	uniprotkb:P47753	intact:EBI-26567598	intact:EBI-777259|uniprotkb:Q91YN7	psi-mi:p97493-pro_0000034151(display_long)|uniprotkb:Thioredoxin-2(gene name synonym)|uniprotkb:Txn2(gene name)|psi-mi:Txn2(display_short)	psi-mi:caza1_mouse(display_long)|uniprotkb:CapZ alpha-1(gene name synonym)|uniprotkb:Capza1(gene name)|psi-mi:Capza1(display_short)|uniprotkb:Cappa1(gene name synonym)	psi-mi:"MI:0096"(pull down)	Chasapis et al. (2019)	pubmed:31018154|imex:IM-28571	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26500418|imex:IM-28571-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	intact:EBI-8354432(chain-parent)	interpro:IPR017865|interpro:IPR002189(F-actin capping protein, alpha subunit)|interpro:IPR042276|interpro:IPR037282|mint:P47753|interpro:IPR042489|go:"GO:0003779"(actin binding)|go:"GO:0005829"(cytosol)|go:"GO:0005903"(brush border)|go:"GO:0005911"(cell-cell junction)|go:"GO:0008290"(F-actin capping protein complex)|go:"GO:0016020"(membrane)|go:"GO:0030036"(actin cytoskeleton organization)|go:"GO:0030863"(cortical cytoskeleton)|go:"GO:0034329"(cell junction assembly)|go:"GO:0051016"(barbed-end actin filament capping)|go:"GO:0071203"(WASH complex)|reactome:R-MMU-2132295|reactome:R-MMU-3371497|reactome:R-MMU-6807878|reactome:R-MMU-6811436|reactome:R-MMU-879415|reactome:R-MMU-983231	-	chain-seq-start:60|chain-seq-end:166	-	figure legend:ST1.7|comment:acid-eluted fraction|dataset:Rare diseases - Interactions investigated in the context of Rare genetic disease|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2020/12/04	2020/12/21	rogid:mvYK6+YgIN/WuGLBCWqsqPLfDyQ10090	rogid:RHqr2/WSAoIXWooDhXO9/TSiTJ010090	rigid:OluZwU5INogvfGGIFu9oRk7nv1c	false	mutation:34-34	-	-	-	psi-mi:"MI:0082"(peptide massfingerprinting)	psi-mi:"MI:0082"(peptide massfingerprinting)
uniprotkb:P97493-PRO_0000034151	uniprotkb:P62259	intact:EBI-26567598	intact:EBI-356480|uniprotkb:P29360|uniprotkb:P42655|uniprotkb:Q63631|ensembl:ENSMUSP00000070993	psi-mi:p97493-pro_0000034151(display_long)|uniprotkb:Thioredoxin-2(gene name synonym)|uniprotkb:Txn2(gene name)|psi-mi:Txn2(display_short)	psi-mi:1433e_mouse(display_long)|uniprotkb:Ywhae(gene name)|psi-mi:Ywhae(display_short)	psi-mi:"MI:0096"(pull down)	Chasapis et al. (2019)	pubmed:31018154|imex:IM-28571	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26500418|imex:IM-28571-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	intact:EBI-8354432(chain-parent)	ensembl:ENSMUSG00000020849(gene)|ensembl:ENSMUST00000067664(transcript)|go:"GO:0000165"(MAPK cascade)|go:"GO:0001764"(neuron migration)|go:"GO:0005246"(calcium channel regulator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0005871"(kinesin complex)|go:"GO:0006605"(protein targeting)|go:"GO:0015459"(potassium channel regulator activity)|go:"GO:0019899"(enzyme binding)|go:"GO:0019903"(protein phosphatase binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0021766"(hippocampus development)|go:"GO:0021987"(cerebral cortex development)|go:"GO:0030424"(axon)|refseq:NP_033562.3|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0034504"(protein localization to nucleus)|go:"GO:0034605"(cellular response to heat)|go:"GO:0035308"(negative regulation of protein dephosphorylation)|go:"GO:0042470"(melanosome)|go:"GO:0042802"(identical protein binding)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045202"(synapse)|go:"GO:0046827"(positive regulation of protein export from nucleus)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0050815"(phosphoserine residue binding)|go:"GO:0051219"(phosphoprotein binding)|go:"GO:0051480"(regulation of cytosolic calcium ion concentration)|go:"GO:0060306"(regulation of membrane repolarization)|go:"GO:0090724"(central region of growth cone)|go:"GO:0097110"(scaffold protein binding)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099072"(regulation of postsynaptic membrane neurotransmitter receptor levels)|go:"GO:1901016"(regulation of potassium ion transmembrane transporter activity)|go:"GO:1901020"(negative regulation of calcium ion transmembrane transporter activity)|go:"GO:1902309"(negative regulation of peptidyl-serine dephosphorylation)|go:"GO:1905913"(negative regulation of calcium ion export across plasma membrane)|interpro:IPR000308(14-3-3 protein)|interpro:IPR023409|interpro:IPR023410|interpro:IPR036815|mint:P62259|reactome:R-MMU-111447|reactome:R-MMU-2028269|reactome:R-MMU-205025|reactome:R-MMU-2565942|reactome:R-MMU-3371453|reactome:R-MMU-3371511|reactome:R-MMU-380259|reactome:R-MMU-380270|reactome:R-MMU-380284|reactome:R-MMU-380320|reactome:R-MMU-5620912|reactome:R-MMU-5625740|reactome:R-MMU-5628897|reactome:R-MMU-75035|reactome:R-MMU-8854518|reactome:R-MMU-8876198	-	chain-seq-start:60|chain-seq-end:166	-	figure legend:ST1.7|comment:acid-eluted fraction|dataset:Rare diseases - Interactions investigated in the context of Rare genetic disease|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2020/12/04	2020/12/21	rogid:mvYK6+YgIN/WuGLBCWqsqPLfDyQ10090	rogid:mnuAjdnQZbMFojll2PnV3xFklXQ10090	rigid:OluZwU5INogvfGGIFu9oRk7nv1c	false	mutation:34-34	-	-	-	psi-mi:"MI:0082"(peptide massfingerprinting)	psi-mi:"MI:0082"(peptide massfingerprinting)
uniprotkb:P97493-PRO_0000034151	uniprotkb:Q9DB29	intact:EBI-26567598	intact:EBI-8362332|intact:MINT-1869552|ensembl:ENSMUSP00000076090	psi-mi:p97493-pro_0000034151(display_long)|uniprotkb:Thioredoxin-2(gene name synonym)|uniprotkb:Txn2(gene name)|psi-mi:Txn2(display_short)	psi-mi:iah1_mouse(display_long)|uniprotkb:Iah1(gene name)|psi-mi:Iah1(display_short)	psi-mi:"MI:0096"(pull down)	Chasapis et al. (2019)	pubmed:31018154|imex:IM-28571	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26500426|imex:IM-28571-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	intact:EBI-8354432(chain-parent)	refseq:NP_080623.2|ensembl:ENSMUSG00000062054(gene)|ensembl:ENSMUST00000076813(transcript)|go:"GO:0016042"(lipid catabolic process)|go:"GO:0016787"(hydrolase activity)|go:"GO:0042802"(identical protein binding)|interpro:IPR013830(Esterase, SGNH hydrolase-type)|interpro:IPR036514|mint:Q9DB29	-	chain-seq-start:60|chain-seq-end:166	function:Probable lipase|comment:mint	figure legend:ST1.8|comment:DTT-eluted fraction|dataset:Rare diseases - Interactions investigated in the context of Rare genetic disease|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2020/12/04	2020/12/21	rogid:mvYK6+YgIN/WuGLBCWqsqPLfDyQ10090	rogid:EsgrBHp1v6tXY4YsteDSPDusTdw10090	rigid:n4xAXAOqYXh1CN68jXiWJ3spgS8	false	mutation:34-34	-	-	-	psi-mi:"MI:0082"(peptide massfingerprinting)	psi-mi:"MI:0082"(peptide massfingerprinting)
uniprotkb:P97493-PRO_0000034151	uniprotkb:Q99NB1	intact:EBI-26567598	intact:EBI-8346875|intact:MINT-4086737|uniprotkb:Q8K0M6|ensembl:ENSMUSP00000028944	psi-mi:p97493-pro_0000034151(display_long)|uniprotkb:Thioredoxin-2(gene name synonym)|uniprotkb:Txn2(gene name)|psi-mi:Txn2(display_short)	psi-mi:acs2l_mouse(display_long)|uniprotkb:Acss1(gene name)|psi-mi:Acss1(display_short)|uniprotkb:Acas2(gene name synonym)|uniprotkb:Acas2l(gene name synonym)|uniprotkb:Acetate--CoA ligase 2(gene name synonym)|uniprotkb:Acetyl-CoA synthetase 2(gene name synonym)|uniprotkb:Acyl-CoA synthetase short-chain family member 1(gene name synonym)|uniprotkb:Propionate--CoA ligase(gene name synonym)	psi-mi:"MI:0096"(pull down)	Chasapis et al. (2019)	pubmed:31018154|imex:IM-28571	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26500426|imex:IM-28571-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	intact:EBI-8354432(chain-parent)	refseq:NP_542142.1|dip:DIP-61209N|ensembl:ENSMUSG00000027452(gene)|ensembl:ENSMUST00000028944(transcript)|go:"GO:0003987"(acetate-CoA ligase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005739"(mitochondrion)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0006085"(acetyl-CoA biosynthetic process)|go:"GO:0016208"(AMP binding)|go:"GO:0019413"(acetate biosynthetic process)|go:"GO:0019427"(acetyl-CoA biosynthetic process from acetate)|go:"GO:0019542"(propionate biosynthetic process)|go:"GO:0050218"(propionate-CoA ligase activity)|interpro:IPR000873(AMP-dependent synthetase and ligase)|interpro:IPR011904(Acetate--CoA ligase)|interpro:IPR020845|interpro:IPR025110|interpro:IPR032387|interpro:IPR042099|mint:Q99NB1|reactome:R-MMU-71384	-	chain-seq-start:60|chain-seq-end:166	function:"Converts acetate to acetyl-CoA so that it can be used for oxidation through the tricarboxylic cycle to produce ATP and CO(2)"|comment:mint	figure legend:ST1.8|comment:DTT-eluted fraction|dataset:Rare diseases - Interactions investigated in the context of Rare genetic disease|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2020/12/04	2020/12/21	rogid:mvYK6+YgIN/WuGLBCWqsqPLfDyQ10090	rogid:h3dcddwI6x6n1h9/eQAdHaNuIMA10090	rigid:n4xAXAOqYXh1CN68jXiWJ3spgS8	false	mutation:34-34	-	-	-	psi-mi:"MI:0082"(peptide massfingerprinting)	psi-mi:"MI:0082"(peptide massfingerprinting)
uniprotkb:P97493-PRO_0000034151	uniprotkb:P17563	intact:EBI-26567598	intact:EBI-8362477|uniprotkb:Q91X87|intact:MINT-1854683|ensembl:ENSMUSP00000088349	psi-mi:p97493-pro_0000034151(display_long)|uniprotkb:Thioredoxin-2(gene name synonym)|uniprotkb:Txn2(gene name)|psi-mi:Txn2(display_short)	psi-mi:sbp1_mouse(display_long)|uniprotkb:Selenbp1(gene name)|psi-mi:Selenbp1(display_short)|uniprotkb:Lpsb(gene name synonym)|uniprotkb:56 kDa selenium-binding protein(gene name synonym)|uniprotkb:Selenium-binding protein 1(gene name synonym)	psi-mi:"MI:0096"(pull down)	Chasapis et al. (2019)	pubmed:31018154|imex:IM-28571	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26500426|imex:IM-28571-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	intact:EBI-8354432(chain-parent)	refseq:NP_033176.2|ensembl:ENSMUSG00000068874(gene)|ensembl:ENSMUST00000090839(transcript)|go:"GO:0001650"(fibrillar center)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0008430"(selenium binding)|go:"GO:0015031"(protein transport)|go:"GO:0016020"(membrane)|go:"GO:0018549"(methanethiol oxidase activity)|go:"GO:0050873"(brown fat cell differentiation)|interpro:IPR008826(Selenium-binding protein)|mint:P17563	-	chain-seq-start:60|chain-seq-end:166	comment:mint|function:Selenium-binding protein which may be involved in the sensing of reactive xenobiotics in the cytoplasm. May be involved in intra-Golgi protein transport	figure legend:ST1.8|comment:DTT-eluted fraction|dataset:Rare diseases - Interactions investigated in the context of Rare genetic disease|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2020/12/04	2020/12/21	rogid:mvYK6+YgIN/WuGLBCWqsqPLfDyQ10090	rogid:/sDrAhh3tD4jaVfdnMSfJSeGAqQ10090	rigid:n4xAXAOqYXh1CN68jXiWJ3spgS8	false	mutation:34-34	-	-	-	psi-mi:"MI:0082"(peptide massfingerprinting)	psi-mi:"MI:0082"(peptide massfingerprinting)
uniprotkb:P97493-PRO_0000034151	uniprotkb:Q7TNG8	intact:EBI-26567598	intact:EBI-8369508|intact:MINT-4116468|uniprotkb:Q8BYU7|uniprotkb:Q8CIV4|ensembl:ENSMUSP00000068086	psi-mi:p97493-pro_0000034151(display_long)|uniprotkb:Thioredoxin-2(gene name synonym)|uniprotkb:Txn2(gene name)|psi-mi:Txn2(display_short)	psi-mi:ldhd_mouse(display_long)|uniprotkb:Ldhd(gene name)|psi-mi:Ldhd(display_short)	psi-mi:"MI:0096"(pull down)	Chasapis et al. (2019)	pubmed:31018154|imex:IM-28571	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26500426|imex:IM-28571-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	intact:EBI-8354432(chain-parent)	refseq:NP_081846.3|ensembl:ENSMUSG00000031958(gene)|ensembl:ENSMUST00000070004(transcript)|go:"GO:0004458"("D-lactate dehydrogenase (cytochrome) activity")|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0006754"(ATP biosynthetic process)|go:"GO:0008720"(D-lactate dehydrogenase activity)|go:"GO:0050660"(flavin adenine dinucleotide binding)|go:"GO:0071949"(FAD binding)|go:"GO:1903457"(lactate catabolic process)|interpro:IPR004113(FAD-linked oxidase, C-terminal)|interpro:IPR006094(FAD linked oxidase, N-terminal)|interpro:IPR016164(FAD-linked oxidase-like, C-terminal)|interpro:IPR016166(FAD-binding, type 2)|interpro:IPR016167(FAD-binding, type 2, subdomain 1)|interpro:IPR016169(CO dehydrogenase flavoprotein-like, FAD-binding, subdomain 2)|interpro:IPR016171(Vanillyl-alcohol oxidase, C-terminal subdomain 2)|interpro:IPR036318|mint:Q7TNG8|reactome:R-MMU-1268020	-	chain-seq-start:60|chain-seq-end:166	comment:mint	figure legend:ST1.8|comment:DTT-eluted fraction|dataset:Rare diseases - Interactions investigated in the context of Rare genetic disease|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2020/12/04	2020/12/21	rogid:mvYK6+YgIN/WuGLBCWqsqPLfDyQ10090	rogid:ajSOKRA5W+b1bTVW5ZNDoPtOkiY10090	rigid:n4xAXAOqYXh1CN68jXiWJ3spgS8	false	mutation:34-34	-	-	-	psi-mi:"MI:0082"(peptide massfingerprinting)	psi-mi:"MI:0082"(peptide massfingerprinting)
uniprotkb:P97493-PRO_0000034151	uniprotkb:Q9DBM2	intact:EBI-26567598	intact:EBI-8362895|uniprotkb:Q91W49|intact:MINT-4121269|ensembl:ENSMUSP00000023559	psi-mi:p97493-pro_0000034151(display_long)|uniprotkb:Thioredoxin-2(gene name synonym)|uniprotkb:Txn2(gene name)|psi-mi:Txn2(display_short)	psi-mi:echp_mouse(display_long)|uniprotkb:Ehhadh(gene name)|psi-mi:Ehhadh(display_short)|uniprotkb:L-pbe(gene name synonym)|uniprotkb:L-peroxisomal bifunctional enzyme(gene name synonym)|uniprotkb:Multifunctional enzyme 1(gene name synonym)|uniprotkb:Multifunctional protein 1(gene name synonym)	psi-mi:"MI:0096"(pull down)	Chasapis et al. (2019)	pubmed:31018154|imex:IM-28571	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26500426|imex:IM-28571-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	intact:EBI-8354432(chain-parent)	refseq:NP_076226.2|ensembl:ENSMUSG00000022853(gene)|ensembl:ENSMUST00000023559(transcript)|go:"GO:0003857"(3-hydroxyacyl-CoA dehydrogenase activity)|go:"GO:0004165"("delta(3)-delta(2)-enoyl-CoA isomerase activity")|go:"GO:0004300"(enoyl-CoA hydratase activity)|go:"GO:0005739"(mitochondrion)|go:"GO:0005777"(peroxisome)|go:"GO:0005829"(cytosol)|go:"GO:0006635"(fatty acid beta-oxidation)|go:"GO:0006637"(acyl-CoA metabolic process)|go:"GO:0016509"(long-chain-3-hydroxyacyl-CoA dehydrogenase activity)|go:"GO:0016863"(intramolecular oxidoreductase activity, transposing C=C bonds)|go:"GO:0019899"(enzyme binding)|go:"GO:0070403"(NAD+ binding)|interpro:IPR001753(Crotonase, core)|interpro:IPR006108(3-hydroxyacyl-CoA dehydrogenase, C-terminal)|interpro:IPR006176(3-hydroxyacyl-CoA dehydrogenase, NAD binding)|interpro:IPR006180(3-hydroxyacyl-CoA dehydrogenase, conserved site)|interpro:IPR008927(6-phosphogluconate dehydrogenase, C-terminal-like)|interpro:IPR018376|interpro:IPR029045|interpro:IPR036291|mint:Q9DBM2|reactome:R-MMU-390247|reactome:R-MMU-9033241	-	chain-seq-start:60|chain-seq-end:166	comment:mint	figure legend:ST1.8|comment:DTT-eluted fraction|dataset:Rare diseases - Interactions investigated in the context of Rare genetic disease|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2020/12/04	2020/12/21	rogid:mvYK6+YgIN/WuGLBCWqsqPLfDyQ10090	rogid:3gdfyvHioP+cRqruPnqQUXDwmQM10090	rigid:n4xAXAOqYXh1CN68jXiWJ3spgS8	false	mutation:34-34	-	-	-	psi-mi:"MI:0082"(peptide massfingerprinting)	psi-mi:"MI:0082"(peptide massfingerprinting)
uniprotkb:P97493-PRO_0000034151	uniprotkb:Q9D6Y7	intact:EBI-26567598	intact:EBI-8318918|intact:MINT-1854772|uniprotkb:Q5EBQ7|uniprotkb:Q91WK9|uniprotkb:Q9DCY2|ensembl:ENSMUSP00000065754	psi-mi:p97493-pro_0000034151(display_long)|uniprotkb:Thioredoxin-2(gene name synonym)|uniprotkb:Txn2(gene name)|psi-mi:Txn2(display_short)	psi-mi:msra_mouse(display_long)|uniprotkb:Msra(gene name)|psi-mi:Msra(display_short)|uniprotkb:Protein-methionine-S-oxide reductase(gene name synonym)|uniprotkb:"Peptide-methionine (S)-S-oxide reductase"(gene name synonym)	psi-mi:"MI:0096"(pull down)	Chasapis et al. (2019)	pubmed:31018154|imex:IM-28571	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26500426|imex:IM-28571-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	intact:EBI-8354432(chain-parent)	refseq:NP_001240641.1|refseq:NP_080598.2|refseq:NP_001240645.1|refseq:NP_001240644.1|refseq:NP_001240643.1|ensembl:ENSMUSG00000054733(gene)|ensembl:ENSMUST00000067927(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0007568"(aging)|go:"GO:0008113"("peptide-methionine (S)-S-oxide reductase activity")|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0034599"(cellular response to oxidative stress)|go:"GO:0036456"("L-methionine-(S)-S-oxide reductase activity")|interpro:IPR002569(Methionine sulphoxide reductase A)|interpro:IPR036509|mint:Q9D6Y7|rcsb pdb:2L90|rcsb pdb:6AGV|reactome:R-MMU-5676934	-	chain-seq-start:60|chain-seq-end:166	comment:mint|function:Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine	figure legend:ST1.8|comment:DTT-eluted fraction|dataset:Rare diseases - Interactions investigated in the context of Rare genetic disease|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2020/12/04	2020/12/21	rogid:mvYK6+YgIN/WuGLBCWqsqPLfDyQ10090	rogid:ImkjyX1WDSFO5VUsJweDFH6MrFA10090	rigid:n4xAXAOqYXh1CN68jXiWJ3spgS8	false	mutation:34-34	-	-	-	psi-mi:"MI:0082"(peptide massfingerprinting)	psi-mi:"MI:0082"(peptide massfingerprinting)
uniprotkb:P97493-PRO_0000034151	uniprotkb:Q9JIL4	intact:EBI-26567598	intact:EBI-7420331|uniprotkb:Q8CDP5|uniprotkb:Q9CQ72|uniprotkb:Q8R4G2|intact:MINT-148595	psi-mi:p97493-pro_0000034151(display_long)|uniprotkb:Thioredoxin-2(gene name synonym)|uniprotkb:Txn2(gene name)|psi-mi:Txn2(display_short)	psi-mi:nhrf3_mouse(display_long)|uniprotkb:Pdzk1(gene name)|psi-mi:Pdzk1(display_short)|uniprotkb:Cap70(gene name synonym)|uniprotkb:Nherf3(gene name synonym)|uniprotkb:PDZ domain-containing protein 1(gene name synonym)|uniprotkb:CFTR-associated protein of 70 kDa(gene name synonym)|uniprotkb:Sodium-hydrogen exchanger regulatory factor 3(gene name synonym)|uniprotkb:"Na(+)/H(+) exchanger regulatory factor 3"(gene name synonym)|uniprotkb:Na/Pi cotransporter C-terminal-associated protein 1(gene name synonym)	psi-mi:"MI:0096"(pull down)	Chasapis et al. (2019)	pubmed:31018154|imex:IM-28571	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26500426|imex:IM-28571-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	intact:EBI-8354432(chain-parent)	mint:Q9JIL4|refseq:XP_011238480.1|refseq:NP_001139473.1|refseq:NP_067492.2|interpro:IPR001478(PDZ/DHR/GLGF)|refseq:XP_017175164.1|go:"GO:0001701"(in utero embryonic development)|go:"GO:0005124"(scavenger receptor binding)|go:"GO:0005886"(plasma membrane)|go:"GO:0005903"(brush border)|go:"GO:0015879"(carnitine transport)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0030165"(PDZ domain binding)|go:"GO:0031526"(brush border membrane)|go:"GO:0031528"(microvillus membrane)|go:"GO:0032414"(positive regulation of ion transmembrane transporter activity)|go:"GO:0043495"(protein-membrane adaptor activity)|go:"GO:0044070"(regulation of anion transport)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045121"(membrane raft)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0090314"(positive regulation of protein targeting to membrane)|go:"GO:1904064"(positive regulation of cation transmembrane transport)|go:"GO:1905477"(positive regulation of protein localization to membrane)|rcsb pdb:2D90|rcsb pdb:2EDZ|rcsb pdb:3NGH|rcsb pdb:3R68|rcsb pdb:3R69|rcsb pdb:4F8K|rcsb pdb:4R2Z|interpro:IPR036034|refseq:XP_006501896.1	-	chain-seq-start:60|chain-seq-end:166	comment:mint|function:"A scaffold protein that connects plasma membrane proteins and regulatory components, regulating their surface expression in epithelial cells apical domains. May be involved in the coordination of a diverse range of regulatory processes for ion transport and second messenger cascades. In complex with SLC9A3R1, may cluster proteins that are functionally dependent in a mutual fashion and modulate the trafficking and the activity of the associated membrane proteins. May play a role in the cellular mechanisms associated with multidrug resistance through its interaction with ABCC2 and PDZK1IP1. May potentiate the CFTR chloride channel activity. May function to connect SCARB1 with the cellular machineries for intracellular cholesterol transport and/or metabolism (By similarity). May be involved in the regulation of proximal tubular Na(+)-dependent inorganic phosphate cotransport therefore playing an important role in tubule function"	figure legend:ST1.8|comment:DTT-eluted fraction|dataset:Rare diseases - Interactions investigated in the context of Rare genetic disease|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2020/12/04	2020/12/21	rogid:mvYK6+YgIN/WuGLBCWqsqPLfDyQ10090	rogid:BJgdvpSO4jt9gOQ4q7csJ928GKI10090	rigid:n4xAXAOqYXh1CN68jXiWJ3spgS8	false	mutation:34-34	-	-	-	psi-mi:"MI:0082"(peptide massfingerprinting)	psi-mi:"MI:0082"(peptide massfingerprinting)
uniprotkb:P97493-PRO_0000034151	uniprotkb:P11930	intact:EBI-26567598	intact:EBI-8361008|intact:MINT-4132945|uniprotkb:B2RS21|ensembl:ENSMUSP00000047778	psi-mi:p97493-pro_0000034151(display_long)|uniprotkb:Thioredoxin-2(gene name synonym)|uniprotkb:Txn2(gene name)|psi-mi:Txn2(display_short)	psi-mi:nud19_mouse(display_long)|uniprotkb:Nucleoside diphosphate-linked moiety X motif 19(gene name synonym)|uniprotkb:Renal CoA diphosphohydrolase(gene name synonym)|uniprotkb:Nudt19(gene name)|psi-mi:Nudt19(display_short)|uniprotkb:D7Rp2e(gene name synonym)|uniprotkb:Testosterone-regulated RP2 protein(gene name synonym)|uniprotkb:Androgen-regulated protein RP2(gene name synonym)	psi-mi:"MI:0096"(pull down)	Chasapis et al. (2019)	pubmed:31018154|imex:IM-28571	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26500426|imex:IM-28571-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	intact:EBI-8354432(chain-parent)	refseq:NP_149071.2|ensembl:ENSMUSG00000034875(gene)|ensembl:ENSMUST00000040962(transcript)|go:"GO:0000287"(magnesium ion binding)|go:"GO:0005739"(mitochondrion)|go:"GO:0005777"(peroxisome)|go:"GO:0015938"(coenzyme A catabolic process)|go:"GO:0016787"(hydrolase activity)|go:"GO:0036114"(medium-chain fatty-acyl-CoA catabolic process)|go:"GO:0044580"(butyryl-CoA catabolic process)|go:"GO:1901289"(succinyl-CoA catabolic process)|go:"GO:1902858"(propionyl-CoA metabolic process)|go:"GO:2001294"(malonyl-CoA catabolic process)|interpro:IPR000086(NUDIX hydrolase, core)|interpro:IPR015797(NUDIX)|interpro:IPR039121|mint:P11930|reactome:R-MMU-390918|reactome:R-MMU-9033241	-	chain-seq-start:60|chain-seq-end:166	function:Acyl-CoA diphosphatase that mediates the hydrolysis of a wide range of CoA esters, including choloyl-CoA and branched-chain fatty-acyl-CoA esters. At low substrate concentrations medium and long-chain fatty-acyl-CoA esters are the primary substrates|comment:mint	figure legend:ST1.8|comment:DTT-eluted fraction|dataset:Rare diseases - Interactions investigated in the context of Rare genetic disease|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2020/12/04	2020/12/21	rogid:mvYK6+YgIN/WuGLBCWqsqPLfDyQ10090	rogid:jyaz8jLgjwbnynk5TlgvmbbTAvs10090	rigid:n4xAXAOqYXh1CN68jXiWJ3spgS8	false	mutation:34-34	-	-	-	psi-mi:"MI:0082"(peptide massfingerprinting)	psi-mi:"MI:0082"(peptide massfingerprinting)
uniprotkb:P97493-PRO_0000034151	uniprotkb:P63323	intact:EBI-26567598	intact:EBI-8328982|intact:MINT-1870296|uniprotkb:P09388|uniprotkb:P12728	psi-mi:p97493-pro_0000034151(display_long)|uniprotkb:Thioredoxin-2(gene name synonym)|uniprotkb:Txn2(gene name)|psi-mi:Txn2(display_short)	psi-mi:rs12_mouse(display_long)|uniprotkb:Rps12(gene name)|psi-mi:Rps12(display_short)	psi-mi:"MI:0096"(pull down)	Chasapis et al. (2019)	pubmed:31018154|imex:IM-28571	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26500426|imex:IM-28571-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	intact:EBI-8354432(chain-parent)	interpro:IPR029064|mint:P63323|interpro:IPR000530(Ribosomal protein S12e)|interpro:IPR004038(Ribosomal protein L7Ae/L30e/S12e/Gadd45)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0006412"(translation)|go:"GO:0022625"(cytosolic large ribosomal subunit)|go:"GO:0022626"(cytosolic ribosome)|go:"GO:0022627"(cytosolic small ribosomal subunit)|go:"GO:0043231"(intracellular membrane-bounded organelle)|reactome:R-MMU-156827|reactome:R-MMU-1799339|reactome:R-MMU-6791226|reactome:R-MMU-72649|reactome:R-MMU-72689|reactome:R-MMU-72695|reactome:R-MMU-72702|reactome:R-MMU-72706|reactome:R-MMU-975956|reactome:R-MMU-975957	-	chain-seq-start:60|chain-seq-end:166	comment:mint	figure legend:ST1.8|comment:DTT-eluted fraction|dataset:Rare diseases - Interactions investigated in the context of Rare genetic disease|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2020/12/04	2020/12/21	rogid:mvYK6+YgIN/WuGLBCWqsqPLfDyQ10090	rogid:7aksQ5txpDO0RK6Wroe/gCuWwj410090	rigid:n4xAXAOqYXh1CN68jXiWJ3spgS8	false	mutation:34-34	-	-	-	psi-mi:"MI:0082"(peptide massfingerprinting)	psi-mi:"MI:0082"(peptide massfingerprinting)
uniprotkb:P97493-PRO_0000034151	uniprotkb:P28825	intact:EBI-26567598	intact:EBI-8363065|uniprotkb:B0V2P9|uniprotkb:Q91WH9|intact:MINT-4121349|ensembl:ENSMUSP00000113838	psi-mi:p97493-pro_0000034151(display_long)|uniprotkb:Thioredoxin-2(gene name synonym)|uniprotkb:Txn2(gene name)|psi-mi:Txn2(display_short)	psi-mi:mep1a_mouse(display_long)|uniprotkb:Endopeptidase-2(gene name synonym)|uniprotkb:MEP-1(gene name synonym)|uniprotkb:Mep1a(gene name)|psi-mi:Mep1a(display_short)	psi-mi:"MI:0096"(pull down)	Chasapis et al. (2019)	pubmed:31018154|imex:IM-28571	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26500426|imex:IM-28571-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	intact:EBI-8354432(chain-parent)	refseq:NP_032611.2|refseq:XP_006523814.1|ensembl:ENSMUSG00000023914(gene)|ensembl:ENSMUST00000117137(transcript)|go:"GO:0004222"(metalloendopeptidase activity)|go:"GO:0008270"(zinc ion binding)|go:"GO:0016020"(membrane)|go:"GO:0017090"(meprin A complex)|interpro:IPR000742(EGF-like, type 3)|interpro:IPR000998(MAM)|interpro:IPR001506(Peptidase M12A, astacin)|interpro:IPR002083(MATH)|interpro:IPR006026(Peptidase, metallopeptidases)|interpro:IPR008294(Peptidase M12A, meprin alpha subunit)|interpro:IPR008974(TRAF-like)|interpro:IPR013320(Concanavalin A-like lectin/glucanase, subgroup)|interpro:IPR024079|interpro:IPR034301|mint:P28825|rcsb pdb:1IAF	-	chain-seq-start:60|chain-seq-end:166	comment:mint	figure legend:ST1.8|comment:DTT-eluted fraction|dataset:Rare diseases - Interactions investigated in the context of Rare genetic disease|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2020/12/04	2020/12/21	rogid:mvYK6+YgIN/WuGLBCWqsqPLfDyQ10090	rogid:CXLX5PggJH5G2j71A0zWg0WPFFk10090	rigid:n4xAXAOqYXh1CN68jXiWJ3spgS8	false	mutation:34-34	-	-	-	psi-mi:"MI:0082"(peptide massfingerprinting)	psi-mi:"MI:0082"(peptide massfingerprinting)
uniprotkb:P97493-PRO_0000034151	uniprotkb:Q9D154	intact:EBI-26567598	intact:EBI-8392973|uniprotkb:Q9D0S8|uniprotkb:Q3TV23|uniprotkb:Q5SUV7|intact:MINT-4127525|uniprotkb:Q9D7S8|ensembl:ENSMUSP00000075690	psi-mi:p97493-pro_0000034151(display_long)|uniprotkb:Thioredoxin-2(gene name synonym)|uniprotkb:Txn2(gene name)|psi-mi:Txn2(display_short)	psi-mi:ileua_mouse(display_long)|uniprotkb:Serpinb1a(gene name)|psi-mi:Serpinb1a(display_short)|uniprotkb:Serpinb1(gene name synonym)|uniprotkb:Serine protease inhibitor EIA(gene name synonym)|uniprotkb:Serpin B1a(gene name synonym)	psi-mi:"MI:0096"(pull down)	Chasapis et al. (2019)	pubmed:31018154|imex:IM-28571	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26500426|imex:IM-28571-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	intact:EBI-8354432(chain-parent)	refseq:NP_079705.2|refseq:XP_006516787.1|ensembl:ENSMUSG00000044734(gene)|ensembl:ENSMUST00000076352(transcript)|go:"GO:0004867"(serine-type endopeptidase inhibitor activity)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0005764"(lysosome)|go:"GO:0005769"(early endosome)|go:"GO:0006954"(inflammatory response)|go:"GO:0010951"(negative regulation of endopeptidase activity)|go:"GO:0019725"(cellular homeostasis)|go:"GO:0030414"(peptidase inhibitor activity)|go:"GO:0032691"(negative regulation of interleukin-1 beta production)|go:"GO:0036464"(cytoplasmic ribonucleoprotein granule)|go:"GO:0042176"(regulation of protein catabolic process)|go:"GO:0044342"(type B pancreatic cell proliferation)|go:"GO:0045088"(regulation of innate immune response)|go:"GO:0062023"(collagen-containing extracellular matrix)|interpro:IPR000215(Protease inhibitor I4, serpin)|interpro:IPR015557(Protease inhibitor I4, serpin B1)|interpro:IPR023795|interpro:IPR023796|interpro:IPR036186|interpro:IPR042178|interpro:IPR042185|mint:Q9D154|reactome:R-MMU-6798695	-	chain-seq-start:60|chain-seq-end:166	comment:mint|function:Regulates the activity of the neutrophil proteases and thus, forms complexes with chymotrypsin, elastase, cathepsin G and proteinase-3	figure legend:ST1.8|comment:DTT-eluted fraction|dataset:Rare diseases - Interactions investigated in the context of Rare genetic disease|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2020/12/04	2020/12/21	rogid:mvYK6+YgIN/WuGLBCWqsqPLfDyQ10090	rogid:L579vV8/0N4vGTUpzFi9vZ4lD0E10090	rigid:n4xAXAOqYXh1CN68jXiWJ3spgS8	false	mutation:34-34	-	-	-	psi-mi:"MI:0082"(peptide massfingerprinting)	psi-mi:"MI:0082"(peptide massfingerprinting)
uniprotkb:P97493-PRO_0000034151	uniprotkb:Q91VM9	intact:EBI-26567598	intact:EBI-8317971|uniprotkb:Q3UPK3|uniprotkb:Q9D1E3|uniprotkb:Q8BTG5|intact:MINT-1843615|ensembl:ENSMUSP00000029644	psi-mi:p97493-pro_0000034151(display_long)|uniprotkb:Thioredoxin-2(gene name synonym)|uniprotkb:Txn2(gene name)|psi-mi:Txn2(display_short)	psi-mi:ipyr2_mouse(display_long)|uniprotkb:Ppa2(gene name)|psi-mi:Ppa2(display_short)|uniprotkb:Pyrophosphate phospho-hydrolase 2(gene name synonym)	psi-mi:"MI:0096"(pull down)	Chasapis et al. (2019)	pubmed:31018154|imex:IM-28571	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26500426|imex:IM-28571-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	intact:EBI-8354432(chain-parent)	refseq:NP_666253.1|refseq:NP_001280570.1|ensembl:ENSMUSG00000028013(gene)|ensembl:ENSMUST00000029644(transcript)|go:"GO:0000287"(magnesium ion binding)|go:"GO:0004427"(inorganic diphosphatase activity)|go:"GO:0004722"(protein serine/threonine phosphatase activity)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0006796"(phosphate-containing compound metabolic process)|go:"GO:0051881"(regulation of mitochondrial membrane potential)|go:"GO:0071344"(diphosphate metabolic process)|interpro:IPR008162(Inorganic pyrophosphatase)|interpro:IPR036649|mint:Q91VM9|reactome:R-MMU-379726|reactome:R-MMU-71737	-	chain-seq-start:60|chain-seq-end:166	comment:mint	figure legend:ST1.8|comment:DTT-eluted fraction|dataset:Rare diseases - Interactions investigated in the context of Rare genetic disease|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2020/12/04	2020/12/21	rogid:mvYK6+YgIN/WuGLBCWqsqPLfDyQ10090	rogid:+E5gorcOyQuWIKOl+IMas9/inRM10090	rigid:n4xAXAOqYXh1CN68jXiWJ3spgS8	false	mutation:34-34	-	-	-	psi-mi:"MI:0082"(peptide massfingerprinting)	psi-mi:"MI:0082"(peptide massfingerprinting)
uniprotkb:P97493-PRO_0000034151	uniprotkb:Q9D819	intact:EBI-26567598	intact:EBI-8317147|intact:MINT-4098757|ensembl:ENSMUSP00000020286	psi-mi:p97493-pro_0000034151(display_long)|uniprotkb:Thioredoxin-2(gene name synonym)|uniprotkb:Txn2(gene name)|psi-mi:Txn2(display_short)	psi-mi:ipyr_mouse(display_long)|uniprotkb:Ppa1(gene name)|psi-mi:Ppa1(display_short)|uniprotkb:Pp(gene name synonym)|uniprotkb:Pyp(gene name synonym)|uniprotkb:Pyrophosphate phospho-hydrolase(gene name synonym)	psi-mi:"MI:0096"(pull down)	Chasapis et al. (2019)	pubmed:31018154|imex:IM-28571	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26500426|imex:IM-28571-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	intact:EBI-8354432(chain-parent)	refseq:NP_080714.2|ensembl:ENSMUSG00000020089(gene)|ensembl:ENSMUST00000020286(transcript)|go:"GO:0000287"(magnesium ion binding)|go:"GO:0004427"(inorganic diphosphatase activity)|go:"GO:0005829"(cytosol)|go:"GO:0006796"(phosphate-containing compound metabolic process)|go:"GO:0016462"(pyrophosphatase activity)|interpro:IPR008162(Inorganic pyrophosphatase)|interpro:IPR036649|mint:Q9D819|reactome:R-MMU-379716|reactome:R-MMU-71737	-	chain-seq-start:60|chain-seq-end:166	comment:mint	figure legend:ST1.8|comment:DTT-eluted fraction|dataset:Rare diseases - Interactions investigated in the context of Rare genetic disease|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2020/12/04	2020/12/21	rogid:mvYK6+YgIN/WuGLBCWqsqPLfDyQ10090	rogid:/YfCFmTO8C51+0zxF3vFnSXcXQs10090	rigid:n4xAXAOqYXh1CN68jXiWJ3spgS8	false	mutation:34-34	-	-	-	psi-mi:"MI:0082"(peptide massfingerprinting)	psi-mi:"MI:0082"(peptide massfingerprinting)
uniprotkb:P97493-PRO_0000034151	uniprotkb:Q8R180	intact:EBI-26567598	intact:EBI-8402056|uniprotkb:Q9CV47|intact:MINT-4094692|uniprotkb:Q9QY03|ensembl:ENSMUSP00000022378	psi-mi:p97493-pro_0000034151(display_long)|uniprotkb:Thioredoxin-2(gene name synonym)|uniprotkb:Txn2(gene name)|psi-mi:Txn2(display_short)	psi-mi:ero1a_mouse(display_long)|uniprotkb:Ero1a(gene name)|psi-mi:Ero1a(display_short)|uniprotkb:Endoplasmic reticulum oxidoreductase alpha(gene name synonym)|uniprotkb:Endoplasmic reticulum oxidoreductin-1-like protein(gene name synonym)|uniprotkb:Ero1l(gene name synonym)|uniprotkb:Oxidoreductin-1-L-alpha(gene name synonym)	psi-mi:"MI:0096"(pull down)	Chasapis et al. (2019)	pubmed:31018154|imex:IM-28571	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26500426|imex:IM-28571-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	intact:EBI-8354432(chain-parent)	refseq:NP_056589.1|ensembl:ENSMUSG00000021831(gene)|ensembl:ENSMUST00000022378(transcript)|go:"GO:0003756"(protein disulfide isomerase activity)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006457"(protein folding)|go:"GO:0006979"(response to oxidative stress)|go:"GO:0010260"(animal organ senescence)|go:"GO:0015035"(protein-disulfide reductase activity)|go:"GO:0016491"(oxidoreductase activity)|go:"GO:0016972"(thiol oxidase activity)|go:"GO:0018401"(peptidyl-proline hydroxylation to 4-hydroxy-L-proline)|go:"GO:0022417"(protein maturation by protein folding)|go:"GO:0030176"(integral component of endoplasmic reticulum membrane)|go:"GO:0030198"(extracellular matrix organization)|go:"GO:0030425"(dendrite)|go:"GO:0030968"(endoplasmic reticulum unfolded protein response)|go:"GO:0034975"(protein folding in endoplasmic reticulum)|go:"GO:0034976"(response to endoplasmic reticulum stress)|go:"GO:0045454"(cell redox homeostasis)|go:"GO:0050873"(brown fat cell differentiation)|go:"GO:0051085"(chaperone cofactor-dependent protein refolding)|go:"GO:0051209"(release of sequestered calcium ion into cytosol)|go:"GO:0070059"(intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress)|go:"GO:0071456"(cellular response to hypoxia)|go:"GO:0071949"(FAD binding)|interpro:IPR007266(Endoplasmic reticulum oxidoreductin 1)|interpro:IPR037192|mint:Q8R180|reactome:R-MMU-264876|reactome:R-MMU-3299685	-	chain-seq-start:60|chain-seq-end:166	comment:mint|function:"Essential oxidoreductase that oxidizes proteins in the endoplasmic reticulum to produce disulfide bonds. Acts by oxidizing directly P4HB/PDI isomerase through a direct disulfide exchange. Does not act as a direct oxidant of folding substrate, but relies on P4HB/PDI to transfer oxidizing equivalent. Associates with TXNDC4 but not with GRP54, demonstrating that it does not oxidize all PDI related proteins and can discriminate between PDI and related proteins. Its reoxidation probably involves electron transfer to molecular oxygen via FAD. Acts independently of glutathione. May be responsible for a significant proportion of reactive oxygen species (ROS) in the cell, thereby being a source of oxidative stress. Required for the folding of immunoglobulin proteins"	figure legend:ST1.8|comment:DTT-eluted fraction|dataset:Rare diseases - Interactions investigated in the context of Rare genetic disease|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2020/12/04	2020/12/21	rogid:mvYK6+YgIN/WuGLBCWqsqPLfDyQ10090	rogid:72qL0BQqSyOiC/ix2dRJF4Z4kWY10090	rigid:n4xAXAOqYXh1CN68jXiWJ3spgS8	false	mutation:34-34	-	-	-	psi-mi:"MI:0082"(peptide massfingerprinting)	psi-mi:"MI:0082"(peptide massfingerprinting)
uniprotkb:P97493-PRO_0000034151	uniprotkb:Q8R3P0	intact:EBI-26567598	intact:EBI-8319421|uniprotkb:Q5SV07|intact:MINT-4086826|uniprotkb:Q9DCE2|uniprotkb:Q9JIN8|uniprotkb:Q9D876|ensembl:ENSMUSP00000021119|ensembl:ENSMUSP00000139318	psi-mi:p97493-pro_0000034151(display_long)|uniprotkb:Thioredoxin-2(gene name synonym)|uniprotkb:Txn2(gene name)|psi-mi:Txn2(display_short)	psi-mi:acy2_mouse(display_long)|uniprotkb:Aspa(gene name)|psi-mi:Aspa(display_short)|uniprotkb:Aminoacylase-2(gene name synonym)	psi-mi:"MI:0096"(pull down)	Chasapis et al. (2019)	pubmed:31018154|imex:IM-28571	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26500426|imex:IM-28571-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	intact:EBI-8354432(chain-parent)	refseq:XP_006532073.2|refseq:NP_075602.2|refseq:XP_006532074.1|refseq:XP_006532075.1|ensembl:ENSMUSG00000020774(gene)|ensembl:ENSMUST00000021119(transcript)|ensembl:ENSMUST00000184572(transcript)|go:"GO:0004046"(aminoacylase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006083"(acetate metabolic process)|go:"GO:0016788"(hydrolase activity, acting on ester bonds)|go:"GO:0016811"("hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides")|go:"GO:0019807"(aspartoacylase activity)|go:"GO:0022010"(central nervous system myelination)|go:"GO:0042802"(identical protein binding)|go:"GO:0046872"(metal ion binding)|go:"GO:0048714"(positive regulation of oligodendrocyte differentiation)|interpro:IPR007036(Succinylglutamate desuccinylase/aspartoacylase)|interpro:IPR016708(Aspartoacylase)|mint:Q8R3P0|reactome:R-MMU-8963693	-	chain-seq-start:60|chain-seq-end:166	comment:mint|function:"Catalyzes the deacetylation of N-acetylaspartic acid (NAA) to produce acetate and L-aspartate. NAA occurs in high concentration in brain and its hydrolysis NAA plays a significant part in the maintenance of intact white matter"	figure legend:ST1.8|comment:DTT-eluted fraction|dataset:Rare diseases - Interactions investigated in the context of Rare genetic disease|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2020/12/04	2020/12/21	rogid:mvYK6+YgIN/WuGLBCWqsqPLfDyQ10090	rogid:vitURXLxvpEcn30yhdWtofbS+wg10090	rigid:n4xAXAOqYXh1CN68jXiWJ3spgS8	false	mutation:34-34	-	-	-	psi-mi:"MI:0082"(peptide massfingerprinting)	psi-mi:"MI:0082"(peptide massfingerprinting)
uniprotkb:P97493-PRO_0000034151	uniprotkb:Q3UZZ6	intact:EBI-26567598	intact:EBI-8361141|uniprotkb:Q6NZD1|uniprotkb:Q9R2C2|intact:MINT-1854922|uniprotkb:O35401|ensembl:ENSMUSP00000108940	psi-mi:p97493-pro_0000034151(display_long)|uniprotkb:Thioredoxin-2(gene name synonym)|uniprotkb:Txn2(gene name)|psi-mi:Txn2(display_short)	psi-mi:st1d1_mouse(display_long)|uniprotkb:Sult1d1(gene name)|psi-mi:Sult1d1(display_short)|uniprotkb:Amine N-sulfotransferase(gene name synonym)|uniprotkb:Dopamine sulfotransferase Sult1d1(gene name synonym)|uniprotkb:St1d1(gene name synonym)|uniprotkb:Tyrosine-ester sulfotransferase(gene name synonym)	psi-mi:"MI:0096"(pull down)	Chasapis et al. (2019)	pubmed:31018154|imex:IM-28571	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26500426|imex:IM-28571-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	intact:EBI-8354432(chain-parent)	refseq:NP_058051.3|ensembl:ENSMUSG00000029273(gene)|ensembl:ENSMUST00000113314(transcript)|go:"GO:0000103"(sulfate assimilation)|go:"GO:0004062"(aryl sulfotransferase activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0006584"(catecholamine metabolic process)|go:"GO:0006629"(lipid metabolic process)|go:"GO:0008146"(sulfotransferase activity)|go:"GO:0051923"(sulfation)|interpro:IPR000863(Sulphotransferase)|interpro:IPR027417|mint:Q3UZZ6|rcsb pdb:2ZPT|rcsb pdb:2ZVP|rcsb pdb:2ZVQ|rcsb pdb:2ZYT|rcsb pdb:2ZYU|rcsb pdb:2ZYV|rcsb pdb:2ZYW	-	chain-seq-start:60|chain-seq-end:166	comment:mint	figure legend:ST1.8|comment:DTT-eluted fraction|dataset:Rare diseases - Interactions investigated in the context of Rare genetic disease|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2020/12/04	2020/12/21	rogid:mvYK6+YgIN/WuGLBCWqsqPLfDyQ10090	rogid:00fu9kHPF5C4KOb+m5yRsXD6E8410090	rigid:n4xAXAOqYXh1CN68jXiWJ3spgS8	false	mutation:34-34	-	-	-	psi-mi:"MI:0082"(peptide massfingerprinting)	psi-mi:"MI:0082"(peptide massfingerprinting)
uniprotkb:P97493-PRO_0000034151	uniprotkb:P17182	intact:EBI-26567598	intact:EBI-299507|ensembl:ENSMUSP00000075513|ensembl:ENSMUSP00000079727|ensembl:ENSMUSP00000157807|uniprotkb:Q99KT7|uniprotkb:Q9DCY7	psi-mi:p97493-pro_0000034151(display_long)|uniprotkb:Thioredoxin-2(gene name synonym)|uniprotkb:Txn2(gene name)|psi-mi:Txn2(display_short)	psi-mi:enoa_mouse(display_long)|uniprotkb:Eno1(gene name)|psi-mi:Eno1(display_short)|uniprotkb:Eno-1(gene name synonym)|uniprotkb:2-phospho-D-glycerate hydro-lyase(gene name synonym)|uniprotkb:Non-neural enolase(gene name synonym)|uniprotkb:Enolase 1(gene name synonym)	psi-mi:"MI:0096"(pull down)	Chasapis et al. (2019)	pubmed:31018154|imex:IM-28571	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26500426|imex:IM-28571-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	intact:EBI-8354432(chain-parent)	ensembl:ENSMUSG00000059040(gene)|ensembl:ENSMUSG00000063524(gene)|ensembl:ENSMUST00000076155(transcript)|ensembl:ENSMUST00000080926(transcript)|ensembl:ENSMUST00000235307(transcript)|go:"GO:0000015"(phosphopyruvate hydratase complex)|go:"GO:0000287"(magnesium ion binding)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0003723"(RNA binding)|go:"GO:0004634"(phosphopyruvate hydratase activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006096"(glycolytic process)|go:"GO:0009986"(cell surface)|go:"GO:0016020"(membrane)|go:"GO:0019897"(extrinsic component of plasma membrane)|go:"GO:0019899"(enzyme binding)|go:"GO:0030426"(growth cone)|go:"GO:0032889"(regulation of vacuole fusion, non-autophagic)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043005"(neuron projection)|go:"GO:0043209"(myelin sheath)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045121"(membrane raft)|go:"GO:0051020"(GTPase binding)|go:"GO:0031072"(heat shock protein binding)|go:"GO:0051099"(positive regulation of binding)|go:"GO:0061621"(canonical glycolysis)|go:"GO:0097060"(synaptic membrane)|go:"GO:0098761"(cellular response to interleukin-7)|go:"GO:0099738"(cell cortex region)|interpro:IPR000941(Enolase)|interpro:IPR020809|interpro:IPR020810|interpro:IPR020811|interpro:IPR029017|interpro:IPR036849|mint:P17182|reactome:R-MMU-70171|reactome:R-MMU-70263|refseq:NP_001020559.1|refseq:NP_075608.2|refseq:XP_006538588.2	-	chain-seq-start:60|chain-seq-end:166	-	figure legend:ST1.8|comment:DTT-eluted fraction|dataset:Rare diseases - Interactions investigated in the context of Rare genetic disease|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2020/12/04	2020/12/21	rogid:mvYK6+YgIN/WuGLBCWqsqPLfDyQ10090	rogid:YFpn/7GDB6vXgCYLSxvNns7FlT410090	rigid:n4xAXAOqYXh1CN68jXiWJ3spgS8	false	mutation:34-34	-	-	-	psi-mi:"MI:0082"(peptide massfingerprinting)	psi-mi:"MI:0082"(peptide massfingerprinting)
uniprotkb:P97493-PRO_0000034151	uniprotkb:Q9R0Y5	intact:EBI-26567598	intact:EBI-777466|uniprotkb:A2AK80|uniprotkb:Q542C5|uniprotkb:Q9R0Y4|ensembl:ENSMUSP00000108902|ensembl:ENSMUSP00000108903	psi-mi:p97493-pro_0000034151(display_long)|uniprotkb:Thioredoxin-2(gene name synonym)|uniprotkb:Txn2(gene name)|psi-mi:Txn2(display_short)	psi-mi:kad1_mouse(display_long)|uniprotkb:ATP-AMP transphosphorylase 1(gene name synonym)|uniprotkb:Myokinase(gene name synonym)|uniprotkb:Ak1(gene name)|psi-mi:Ak1(display_short)|uniprotkb:"ATP:AMP phosphotransferase"(gene name synonym)|uniprotkb:Adenylate monophosphate kinase(gene name synonym)	psi-mi:"MI:0096"(pull down)	Chasapis et al. (2019)	pubmed:31018154|imex:IM-28571	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26500426|imex:IM-28571-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	intact:EBI-8354432(chain-parent)	refseq:NP_001185719.1|refseq:NP_001185720.1|refseq:NP_001185721.1|refseq:NP_067490.1|refseq:XP_006497687.1|ensembl:ENSMUSG00000026817(gene)|ensembl:ENSMUST00000113277(transcript)|ensembl:ENSMUST00000113278(transcript)|go:"GO:0001520"(outer dense fiber)|go:"GO:0004017"(adenylate kinase activity)|go:"GO:0004550"(nucleoside diphosphate kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006165"(nucleoside diphosphate phosphorylation)|go:"GO:0006172"(ADP biosynthetic process)|go:"GO:0009142"(nucleoside triphosphate biosynthetic process)|go:"GO:0010828"(positive regulation of glucose transmembrane transport)|go:"GO:0030017"(sarcomere)|go:"GO:0036126"(sperm flagellum)|go:"GO:0043005"(neuron projection)|go:"GO:0046033"(AMP metabolic process)|go:"GO:0046034"(ATP metabolic process)|go:"GO:0046103"(inosine biosynthetic process)|go:"GO:0048471"(perinuclear region of cytoplasm)|interpro:IPR000850(Adenylate kinase)|interpro:IPR006267(Adenylate kinase, isozyme 1)|interpro:IPR027417|interpro:IPR028582|interpro:IPR033690|mint:Q9R0Y5|reactome:R-MMU-499943	-	chain-seq-start:60|chain-seq-end:166	-	figure legend:ST1.8|comment:DTT-eluted fraction|dataset:Rare diseases - Interactions investigated in the context of Rare genetic disease|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2020/12/04	2020/12/21	rogid:mvYK6+YgIN/WuGLBCWqsqPLfDyQ10090	rogid:HTydMeIFNEaVZDs7sEN7aLieuVg10090	rigid:n4xAXAOqYXh1CN68jXiWJ3spgS8	false	mutation:34-34	-	-	-	psi-mi:"MI:0082"(peptide massfingerprinting)	psi-mi:"MI:0082"(peptide massfingerprinting)
uniprotkb:P97493-PRO_0000034151	uniprotkb:Q99KI0	intact:EBI-26567598	intact:EBI-444886|uniprotkb:Q3UDK9|uniprotkb:Q3ULG9|uniprotkb:Q3UNH7|uniprotkb:Q505P4|ensembl:ENSMUSP00000023116	psi-mi:p97493-pro_0000034151(display_long)|uniprotkb:Thioredoxin-2(gene name synonym)|uniprotkb:Txn2(gene name)|psi-mi:Txn2(display_short)	psi-mi:acon_mouse(display_long)|uniprotkb:Citrate hydro-lyase(gene name synonym)|uniprotkb:Aco2(gene name)|psi-mi:Aco2(display_short)	psi-mi:"MI:0096"(pull down)	Chasapis et al. (2019)	pubmed:31018154|imex:IM-28571	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26500426|imex:IM-28571-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	intact:EBI-8354432(chain-parent)	refseq:NP_542364.1|ensembl:ENSMUSG00000022477(gene)|ensembl:ENSMUST00000023116(transcript)|go:"GO:0001889"(liver development)|go:"GO:0003994"(aconitate hydratase activity)|go:"GO:0005506"(iron ion binding)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0006099"(tricarboxylic acid cycle)|go:"GO:0006101"(citrate metabolic process)|go:"GO:0006102"(isocitrate metabolic process)|go:"GO:0035900"(response to isolation stress)|go:"GO:0043209"(myelin sheath)|go:"GO:0047780"(citrate dehydratase activity)|go:"GO:0051538"(3 iron, 4 sulfur cluster binding)|go:"GO:0051539"(4 iron, 4 sulfur cluster binding)|interpro:IPR000573(Aconitase A/isopropylmalate dehydratase small subunit, swivel)|interpro:IPR001030(Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha)|interpro:IPR006248(Aconitase, mitochondrial-like)|interpro:IPR015932(Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha, subdomain 2)|interpro:IPR018136|interpro:IPR036008|mint:Q99KI0|reactome:R-MMU-71403|interpro:IPR015928(Aconitase/3-isopropylmalate dehydratase, swivel)|interpro:IPR015931(Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha, subdomains 1 and 3)	-	chain-seq-start:60|chain-seq-end:166	-	figure legend:ST1.8|comment:DTT-eluted fraction|dataset:Rare diseases - Interactions investigated in the context of Rare genetic disease|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2020/12/04	2020/12/21	rogid:mvYK6+YgIN/WuGLBCWqsqPLfDyQ10090	rogid:0NOVcGhBwl4qmtnlhX9jcsQMdSo10090	rigid:n4xAXAOqYXh1CN68jXiWJ3spgS8	false	mutation:34-34	-	-	-	psi-mi:"MI:0082"(peptide massfingerprinting)	psi-mi:"MI:0082"(peptide massfingerprinting)
uniprotkb:P97493-PRO_0000034151	uniprotkb:Q91YR1	intact:EBI-26567598	intact:EBI-527441|uniprotkb:Q52L77|uniprotkb:Q80X09|uniprotkb:O09132|ensembl:ENSMUSP00000023087	psi-mi:p97493-pro_0000034151(display_long)|uniprotkb:Thioredoxin-2(gene name synonym)|uniprotkb:Txn2(gene name)|psi-mi:Txn2(display_short)	psi-mi:twf1_mouse(display_long)|uniprotkb:Protein A6(gene name synonym)|uniprotkb:Twf1(gene name)|psi-mi:Twf1(display_short)|uniprotkb:Ptk9(gene name synonym)	psi-mi:"MI:0096"(pull down)	Chasapis et al. (2019)	pubmed:31018154|imex:IM-28571	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26500426|imex:IM-28571-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	intact:EBI-8354432(chain-parent)	dip:DIP-33923N|refseq:NP_032997.3|ensembl:ENSMUSG00000022451(gene)|ensembl:ENSMUST00000023087(transcript)|go:"GO:0003779"(actin binding)|go:"GO:0003785"(actin monomer binding)|go:"GO:0004713"(protein tyrosine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005546"(phosphatidylinositol-4,5-bisphosphate binding)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005884"(actin filament)|go:"GO:0005911"(cell-cell junction)|go:"GO:0010591"(regulation of lamellipodium assembly)|go:"GO:0010613"(positive regulation of cardiac muscle hypertrophy)|go:"GO:0010976"(positive regulation of neuron projection development)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0030016"(myofibril)|go:"GO:0030042"(actin filament depolymerization)|go:"GO:0030175"(filopodium)|go:"GO:0030837"(negative regulation of actin filament polymerization)|go:"GO:0042989"(sequestering of actin monomers)|go:"GO:0043538"(regulation of actin phosphorylation)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051015"(actin filament binding)|go:"GO:0051016"(barbed-end actin filament capping)|interpro:IPR002108(Actin-binding, cofilin/tropomyosin type)|interpro:IPR028458|interpro:IPR029006|mint:Q91YR1|rcsb pdb:1M4J|rcsb pdb:2D8B|rcsb pdb:2HD7|rcsb pdb:3DAW|rcsb pdb:6RSW|rcsb pdb:6YP9|rcsb pdb:7DS2|rcsb pdb:7DS4|rcsb pdb:7DS6|rcsb pdb:7DS8|rcsb pdb:7DSB|reactome:R-MMU-9013418	-	chain-seq-start:60|chain-seq-end:166	-	figure legend:ST1.8|comment:DTT-eluted fraction|dataset:Rare diseases - Interactions investigated in the context of Rare genetic disease|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2020/12/04	2020/12/21	rogid:mvYK6+YgIN/WuGLBCWqsqPLfDyQ10090	rogid:GgCN343v3YPfA5sIWax5s80Yjuc10090	rigid:n4xAXAOqYXh1CN68jXiWJ3spgS8	false	mutation:34-34	-	-	-	psi-mi:"MI:0082"(peptide massfingerprinting)	psi-mi:"MI:0082"(peptide massfingerprinting)
uniprotkb:P97493-PRO_0000034151	uniprotkb:P68368	intact:EBI-26567598	intact:EBI-2642970|uniprotkb:Q3TY31|uniprotkb:P05215|ensembl:ENSMUSP00000140657	psi-mi:p97493-pro_0000034151(display_long)|uniprotkb:Thioredoxin-2(gene name synonym)|uniprotkb:Txn2(gene name)|psi-mi:Txn2(display_short)	psi-mi:tba4a_mouse(display_long)|uniprotkb:Tuba4a(gene name)|psi-mi:Tuba4a(display_short)|uniprotkb:Tuba4(gene name synonym)|uniprotkb:Tubulin alpha-4 chain(gene name synonym)|uniprotkb:Alpha-tubulin 4(gene name synonym)|uniprotkb:Alpha-tubulin isotype M-alpha-4(gene name synonym)	psi-mi:"MI:0096"(pull down)	Chasapis et al. (2019)	pubmed:31018154|imex:IM-28571	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26500426|imex:IM-28571-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	intact:EBI-8354432(chain-parent)	refseq:NP_033473.1|ensembl:ENSMUSG00000026202(gene)|ensembl:ENSMUST00000186213(transcript)|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0005200"(structural constituent of cytoskeleton)|go:"GO:0005525"(GTP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005874"(microtubule)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0019899"(enzyme binding)|go:"GO:0019901"(protein kinase binding)|interpro:IPR000217(Tubulin)|interpro:IPR002452(Alpha tubulin)|interpro:IPR003008(Tubulin/FtsZ, GTPase)|interpro:IPR008280(Tubulin/FtsZ, C-terminal)|interpro:IPR017975|interpro:IPR018316|interpro:IPR023123|interpro:IPR036525|interpro:IPR037103|mint:P68368|reactome:R-MMU-114608|reactome:R-MMU-190840|reactome:R-MMU-2467813|reactome:R-MMU-2500257|reactome:R-MMU-2565942|reactome:R-MMU-3371497|reactome:R-MMU-380259|reactome:R-MMU-380270|reactome:R-MMU-380284|reactome:R-MMU-380320|reactome:R-MMU-437239|reactome:R-MMU-5610787|reactome:R-MMU-5617833|reactome:R-MMU-5620912|reactome:R-MMU-5620924|reactome:R-MMU-5626467|reactome:R-MMU-5663220|reactome:R-MMU-6807878|reactome:R-MMU-6811434|reactome:R-MMU-6811436|reactome:R-MMU-68877|reactome:R-MMU-8852276|reactome:R-MMU-8854518|reactome:R-MMU-8955332|reactome:R-MMU-9646399|reactome:R-MMU-9648025|reactome:R-MMU-9668328|reactome:R-MMU-983189|reactome:R-MMU-2132295	-	chain-seq-start:60|chain-seq-end:166	-	figure legend:ST1.8|comment:DTT-eluted fraction|dataset:Rare diseases - Interactions investigated in the context of Rare genetic disease|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2020/12/04	2020/12/21	rogid:mvYK6+YgIN/WuGLBCWqsqPLfDyQ10090	rogid:6Oj9O8u7E6cLUJ1eT6y5slbk7uQ10090	rigid:n4xAXAOqYXh1CN68jXiWJ3spgS8	false	mutation:34-34	-	-	-	psi-mi:"MI:0082"(peptide massfingerprinting)	psi-mi:"MI:0082"(peptide massfingerprinting)
uniprotkb:P97493-PRO_0000034151	uniprotkb:P20108	intact:EBI-26567598	intact:EBI-309031|ensembl:ENSMUSP00000025961	psi-mi:p97493-pro_0000034151(display_long)|uniprotkb:Thioredoxin-2(gene name synonym)|uniprotkb:Txn2(gene name)|psi-mi:Txn2(display_short)	psi-mi:prdx3_mouse(display_long)|uniprotkb:Prdx3(gene name)|psi-mi:Prdx3(display_short)|uniprotkb:Aop1(gene name synonym)|uniprotkb:Mer5(gene name synonym)|uniprotkb:Perioredoxin-3(gene name synonym)|uniprotkb:PRX III(gene name synonym)|uniprotkb:Antioxidant protein 1(gene name synonym)|uniprotkb:Protein MER5(gene name synonym)|uniprotkb:Thioredoxin-dependent peroxiredoxin 3(gene name synonym)	psi-mi:"MI:0096"(pull down)	Chasapis et al. (2019)	pubmed:31018154|imex:IM-28571	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26500426|imex:IM-28571-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	intact:EBI-8354432(chain-parent)	ensembl:ENSMUSG00000024997(gene)|ensembl:ENSMUST00000025961(transcript)|go:"GO:0001893"(maternal placenta development)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005769"(early endosome)|go:"GO:0005829"(cytosol)|go:"GO:0006979"(response to oxidative stress)|go:"GO:0007005"(mitochondrion organization)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0008379"(thioredoxin peroxidase activity)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0018171"(peptidyl-cysteine oxidation)|go:"GO:0043209"(myelin sheath)|go:"GO:0019900"(kinase binding)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0045454"(cell redox homeostasis)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|go:"GO:0051881"(regulation of mitochondrial membrane potential)|interpro:IPR000866(Alkyl hydroperoxide reductase/ Thiol specific antioxidant/ Mal allergen)|interpro:IPR013766(Thioredoxin domain)|interpro:IPR019479|interpro:IPR036249|mint:P20108|reactome:R-MMU-3299685|go:"GO:0019901"(protein kinase binding)|go:"GO:0030099"(myeloid cell differentiation)|go:"GO:0032496"(response to lipopolysaccharide)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033673"(negative regulation of kinase activity)|go:"GO:0034599"(cellular response to oxidative stress)|go:"GO:0034614"(cellular response to reactive oxygen species)|go:"GO:0042542"(response to hydrogen peroxide)|go:"GO:0042744"(hydrogen peroxide catabolic process)|go:"GO:0042802"(identical protein binding)|go:"GO:0043027"(cysteine-type endopeptidase inhibitor activity involved in apoptotic process)|refseq:NP_031478.1	-	chain-seq-start:60|chain-seq-end:166	-	figure legend:ST1.8|comment:DTT-eluted fraction|dataset:Rare diseases - Interactions investigated in the context of Rare genetic disease|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2020/12/04	2020/12/21	rogid:mvYK6+YgIN/WuGLBCWqsqPLfDyQ10090	rogid:BGMQPun3/Vu7SSlj8rdWV+PU48Q10090	rigid:n4xAXAOqYXh1CN68jXiWJ3spgS8	false	mutation:34-34	-	-	-	psi-mi:"MI:0082"(peptide massfingerprinting)	psi-mi:"MI:0082"(peptide massfingerprinting)
uniprotkb:P97493-PRO_0000034151	uniprotkb:Q9D1Q6	intact:EBI-26567598	intact:EBI-541567|uniprotkb:Q3TVI1|uniprotkb:Q6A045|ensembl:ENSMUSP00000030028	psi-mi:p97493-pro_0000034151(display_long)|uniprotkb:Thioredoxin-2(gene name synonym)|uniprotkb:Txn2(gene name)|psi-mi:Txn2(display_short)	psi-mi:erp44_mouse(display_long)|uniprotkb:Erp44(gene name)|psi-mi:Erp44(display_short)|uniprotkb:Txndc4(gene name synonym)|uniprotkb:Thioredoxin domain-containing protein 4(gene name synonym)|uniprotkb:Kiaa0573(gene name synonym)	psi-mi:"MI:0096"(pull down)	Chasapis et al. (2019)	pubmed:31018154|imex:IM-28571	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26500426|imex:IM-28571-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	intact:EBI-8354432(chain-parent)	ensembl:ENSMUSG00000028343(gene)|ensembl:ENSMUST00000030028(transcript)|go:"GO:0003756"(protein disulfide isomerase activity)|go:"GO:0005788"(endoplasmic reticulum lumen)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005793"(endoplasmic reticulum-Golgi intermediate compartment)|go:"GO:0006457"(protein folding)|go:"GO:0006986"(response to unfolded protein)|go:"GO:0009100"(glycoprotein metabolic process)|go:"GO:0009986"(cell surface)|go:"GO:0034976"(response to endoplasmic reticulum stress)|interpro:IPR013766(Thioredoxin domain)|interpro:IPR036249|interpro:IPR041862|interpro:IPR041870|mint:Q9D1Q6|reactome:R-MMU-6798695|refseq:NP_083848.1	-	chain-seq-start:60|chain-seq-end:166	-	figure legend:ST1.8|comment:DTT-eluted fraction|dataset:Rare diseases - Interactions investigated in the context of Rare genetic disease|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2020/12/04	2020/12/21	rogid:mvYK6+YgIN/WuGLBCWqsqPLfDyQ10090	rogid:qBveThXqKoa1frYst8WJ8q5/pPg10090	rigid:n4xAXAOqYXh1CN68jXiWJ3spgS8	false	mutation:34-34	-	-	-	psi-mi:"MI:0082"(peptide massfingerprinting)	psi-mi:"MI:0082"(peptide massfingerprinting)
uniprotkb:P97493-PRO_0000034151	uniprotkb:Q9D5V6	intact:EBI-26567598	intact:EBI-26499304|ensembl:ENSMUSP00000033723|uniprotkb:Q3UI67|uniprotkb:Q9D870	psi-mi:p97493-pro_0000034151(display_long)|uniprotkb:Thioredoxin-2(gene name synonym)|uniprotkb:Txn2(gene name)|psi-mi:Txn2(display_short)	psi-mi:syap1_mouse(display_long)|uniprotkb:Syap1(gene name)|psi-mi:Syap1(display_short)|uniprotkb:BSD domain-containing signal transducer and Akt interactor protein(gene name synonym)	psi-mi:"MI:0096"(pull down)	Chasapis et al. (2019)	pubmed:31018154|imex:IM-28571	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26500426|imex:IM-28571-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	intact:EBI-8354432(chain-parent)	ensembl:ENSMUSG00000031357(gene)|ensembl:ENSMUST00000033723(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0030154"(cell differentiation)|go:"GO:0030424"(axon)|go:"GO:0030425"(dendrite)|go:"GO:0030426"(growth cone)|go:"GO:0031234"(extrinsic component of cytoplasmic side of plasma membrane)|go:"GO:0032869"(cellular response to insulin stimulus)|go:"GO:0036120"(cellular response to platelet-derived growth factor stimulus)|go:"GO:0038203"(TORC2 signaling)|go:"GO:0042734"(presynaptic membrane)|go:"GO:0043204"(perikaryon)|go:"GO:0045211"(postsynaptic membrane)|go:"GO:0045600"(positive regulation of fat cell differentiation)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0071364"(cellular response to epidermal growth factor stimulus)|go:"GO:0071902"(positive regulation of protein serine/threonine kinase activity)|go:"GO:1990314"(cellular response to insulin-like growth factor stimulus)|interpro:IPR005607(BSD)|interpro:IPR035925|mint:Q9D5V6|refseq:NP_080208.2	-	chain-seq-start:60|chain-seq-end:166	-	figure legend:ST1.8|comment:DTT-eluted fraction|dataset:Rare diseases - Interactions investigated in the context of Rare genetic disease|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2020/12/04	2020/12/21	rogid:mvYK6+YgIN/WuGLBCWqsqPLfDyQ10090	rogid:46qN+WDDU6nJo/BWzvUndVAd5gg10090	rigid:n4xAXAOqYXh1CN68jXiWJ3spgS8	false	mutation:34-34	-	-	-	psi-mi:"MI:0082"(peptide massfingerprinting)	psi-mi:"MI:0082"(peptide massfingerprinting)
uniprotkb:P97493-PRO_0000034151	uniprotkb:P38647	intact:EBI-26567598	intact:EBI-772469|uniprotkb:Q9CQ05|intact:EBI-4282065|uniprotkb:Q3TW93|uniprotkb:Q3UVN1|uniprotkb:Q3V015|intact:EBI-1635058|uniprotkb:Q7TSZ0|ensembl:ENSMUSP00000025217	psi-mi:p97493-pro_0000034151(display_long)|uniprotkb:Thioredoxin-2(gene name synonym)|uniprotkb:Txn2(gene name)|psi-mi:Txn2(display_short)	psi-mi:grp75_mouse(display_long)|uniprotkb:75 kDa glucose-regulated protein(gene name synonym)|uniprotkb:p66 MOT(gene name synonym)|uniprotkb:Heat shock 70 kDa protein 9(gene name synonym)|uniprotkb:Peptide-binding protein 74(gene name synonym)|uniprotkb:Mortalin(gene name synonym)|uniprotkb:Hspa9(gene name)|psi-mi:Hspa9(display_short)|uniprotkb:Grp75(gene name synonym)|uniprotkb:Hsp74(gene name synonym)|uniprotkb:Hspa9a(gene name synonym)	psi-mi:"MI:0096"(pull down)	Chasapis et al. (2019)	pubmed:31018154|imex:IM-28571	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26500426|imex:IM-28571-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	intact:EBI-8354432(chain-parent)	refseq:NP_034611.2|ensembl:ENSMUSG00000024359(gene)|ensembl:ENSMUST00000025217(transcript)|go:"GO:0005524"(ATP binding)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0006611"(protein export from nucleus)|go:"GO:0016226"(iron-sulfur cluster assembly)|go:"GO:0017134"(fibroblast growth factor binding)|go:"GO:0019899"(enzyme binding)|go:"GO:0030218"(erythrocyte differentiation)|go:"GO:0031072"(heat shock protein binding)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0034620"(cellular response to unfolded protein)|go:"GO:0042026"(protein refolding)|go:"GO:0042645"(mitochondrial nucleoid)|go:"GO:0043209"(myelin sheath)|go:"GO:0044183"(protein folding chaperone)|go:"GO:0045646"(regulation of erythrocyte differentiation)|go:"GO:0045647"(negative regulation of erythrocyte differentiation)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0051085"(chaperone cofactor-dependent protein refolding)|go:"GO:0051087"(chaperone binding)|go:"GO:0051787"(misfolded protein binding)|go:"GO:0060548"(negative regulation of cell death)|go:"GO:1902037"(negative regulation of hematopoietic stem cell differentiation)|go:"GO:1903707"(negative regulation of hemopoiesis)|interpro:IPR012725(Chaperone DnaK)|interpro:IPR013126(Heat shock protein 70)|interpro:IPR018181|interpro:IPR029047|interpro:IPR029048|interpro:IPR043129|mint:P38647|reactome:R-MMU-3371453	-	chain-seq-start:60|chain-seq-end:166	-	figure legend:ST1.8|comment:DTT-eluted fraction|dataset:Rare diseases - Interactions investigated in the context of Rare genetic disease|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2020/12/04	2020/12/21	rogid:mvYK6+YgIN/WuGLBCWqsqPLfDyQ10090	rogid:HyohIe5BGD5mW3UO0OekqUKOhbU10090	rigid:n4xAXAOqYXh1CN68jXiWJ3spgS8	false	mutation:34-34	-	-	-	psi-mi:"MI:0082"(peptide massfingerprinting)	psi-mi:"MI:0082"(peptide massfingerprinting)
uniprotkb:P97493-PRO_0000034151	uniprotkb:Q63836	intact:EBI-26567598	intact:EBI-1371777|uniprotkb:Q8R1T6	psi-mi:p97493-pro_0000034151(display_long)|uniprotkb:Thioredoxin-2(gene name synonym)|uniprotkb:Txn2(gene name)|psi-mi:Txn2(display_short)	psi-mi:sbp2_mouse(display_long)|uniprotkb:Selenbp2(gene name)|psi-mi:Selenbp2(display_short)|uniprotkb:Lpsb2(gene name synonym)|uniprotkb:56 kDa acetaminophen-binding protein(gene name synonym)	psi-mi:"MI:0096"(pull down)	Chasapis et al. (2019)	pubmed:31018154|imex:IM-28571	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26500426|imex:IM-28571-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	intact:EBI-8354432(chain-parent)	refseq:NP_062287.1|interpro:IPR008826(Selenium-binding protein)|mint:Q63836|go:"GO:0001650"(fibrillar center)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0008430"(selenium binding)|go:"GO:0015031"(protein transport)|go:"GO:0016020"(membrane)	-	chain-seq-start:60|chain-seq-end:166	-	figure legend:ST1.8|comment:DTT-eluted fraction|dataset:Rare diseases - Interactions investigated in the context of Rare genetic disease|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2020/12/04	2020/12/21	rogid:mvYK6+YgIN/WuGLBCWqsqPLfDyQ10090	rogid:E/xxMHifa3vpfQexdSnn7gZN9Ws10090	rigid:n4xAXAOqYXh1CN68jXiWJ3spgS8	false	mutation:34-34	-	-	-	psi-mi:"MI:0082"(peptide massfingerprinting)	psi-mi:"MI:0082"(peptide massfingerprinting)
uniprotkb:P97493-PRO_0000034151	uniprotkb:P63038	intact:EBI-26567598	intact:EBI-299343|ensembl:ENSMUSP00000027123|uniprotkb:P19226|uniprotkb:P19227|uniprotkb:P97602|uniprotkb:Q3KQP2|uniprotkb:Q3UIP0|uniprotkb:Q8C2C7|uniprotkb:Q8VEF4	psi-mi:p97493-pro_0000034151(display_long)|uniprotkb:Thioredoxin-2(gene name synonym)|uniprotkb:Txn2(gene name)|psi-mi:Txn2(display_short)	psi-mi:ch60_mouse(display_long)|uniprotkb:Hspd1(gene name)|psi-mi:Hspd1(display_short)|uniprotkb:Hsp60(gene name synonym)|uniprotkb:Heat shock protein 60(gene name synonym)|uniprotkb:60 kDa chaperonin(gene name synonym)|uniprotkb:Chaperonin 60(gene name synonym)|uniprotkb:Mitochondrial matrix protein P1(gene name synonym)|uniprotkb:HSP-65(gene name synonym)	psi-mi:"MI:0096"(pull down)	Chasapis et al. (2019)	pubmed:31018154|imex:IM-28571	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26500426|imex:IM-28571-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	intact:EBI-8354432(chain-parent)	ensembl:ENSMUSG00000025980(gene)|ensembl:ENSMUST00000027123(transcript)|go:"GO:0001530"(lipopolysaccharide binding)|go:"GO:0001666"(response to hypoxia)|go:"GO:0002039"(p53 binding)|go:"GO:0002755"(MyD88-dependent toll-like receptor signaling pathway)|go:"GO:0002842"(positive regulation of T cell mediated immune response to tumor cell)|go:"GO:0002931"(response to ischemia)|go:"GO:0003725"(double-stranded RNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0005769"(early endosome)|go:"GO:0005782"(peroxisomal matrix)|go:"GO:0005791"(rough endoplasmic reticulum)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005905"(clathrin-coated pit)|go:"GO:0006457"(protein folding)|go:"GO:0006919"(activation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0006986"(response to unfolded protein)|go:"GO:0008035"(high-density lipoprotein particle binding)|go:"GO:0008637"(apoptotic mitochondrial changes)|go:"GO:0009409"(response to cold)|go:"GO:0009986"(cell surface)|go:"GO:0014823"(response to activity)|go:"GO:0016020"(membrane)|go:"GO:0016853"(isomerase activity)|go:"GO:0019899"(enzyme binding)|go:"GO:0030061"(mitochondrial crista)|go:"GO:0030135"(coated vesicle)|go:"GO:0030141"(secretory granule)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0031985"(Golgi cisterna)|go:"GO:0032496"(response to lipopolysaccharide)|go:"GO:0032727"(positive regulation of interferon-alpha production)|go:"GO:0032729"(positive regulation of interferon-gamma production)|go:"GO:0032733"(positive regulation of interleukin-10 production)|go:"GO:0032735"(positive regulation of interleukin-12 production)|go:"GO:0032755"(positive regulation of interleukin-6 production)|go:"GO:0032760"(positive regulation of tumor necrosis factor production)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033198"(response to ATP)|go:"GO:0034185"(apolipoprotein binding)|go:"GO:0034186"(apolipoprotein A-I binding)|go:"GO:0034514"(mitochondrial unfolded protein response)|go:"GO:0034605"(cellular response to heat)|go:"GO:0042026"(protein refolding)|go:"GO:0042100"(B cell proliferation)|go:"GO:0042110"(T cell activation)|go:"GO:0042113"(B cell activation)|go:"GO:0042220"(response to cocaine)|go:"GO:0042493"|go:"GO:0042542"(response to hydrogen peroxide)|go:"GO:0042588"(zymogen granule)|go:"GO:0043032"(positive regulation of macrophage activation)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043209"(myelin sheath)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0043627"(response to estrogen)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045041"(protein import into mitochondrial intermembrane space)|go:"GO:0045121"(membrane raft)|go:"GO:0046696"(lipopolysaccharide receptor complex)|go:"GO:0048291"(isotype switching to IgG isotypes)|go:"GO:0050729"(positive regulation of inflammatory response)|go:"GO:0050821"(protein stabilization)|go:"GO:0050870"(positive regulation of T cell activation)|go:"GO:0051087"(chaperone binding)|go:"GO:0051384"(response to glucocorticoid)|go:"GO:0051702"(biological process involved in interaction with symbiont)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071866"(negative regulation of apoptotic process in bone marrow cell)|go:"GO:0097225"(sperm midpiece)|go:"GO:0098761"(cellular response to interleukin-7)|go:"GO:0140030"(modification-dependent protein binding)|go:"GO:1903427"(negative regulation of reactive oxygen species biosynthetic process)|interpro:IPR001844(Chaperonin Cpn60)|interpro:IPR002423(Chaperonin Cpn60/TCP-1)|interpro:IPR018370|interpro:IPR027409|interpro:IPR027410|interpro:IPR027413|mint:P63038|reactome:R-MMU-1268020|refseq:XP_006495769.1|refseq:NP_034607.3|dip:DIP-31396N	-	chain-seq-start:60|chain-seq-end:166	-	figure legend:ST1.8|comment:DTT-eluted fraction|dataset:Rare diseases - Interactions investigated in the context of Rare genetic disease|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2020/12/04	2020/12/21	rogid:mvYK6+YgIN/WuGLBCWqsqPLfDyQ10090	rogid:WD1fQLh4I0ovpakE8KtM1R0XpL410090	rigid:n4xAXAOqYXh1CN68jXiWJ3spgS8	false	mutation:34-34	-	-	-	psi-mi:"MI:0082"(peptide massfingerprinting)	psi-mi:"MI:0082"(peptide massfingerprinting)
uniprotkb:P97493-PRO_0000034151	uniprotkb:O08709	intact:EBI-26567598	intact:EBI-444895|uniprotkb:Q91WT2|uniprotkb:Q9QWP4|uniprotkb:Q9QWW0	psi-mi:p97493-pro_0000034151(display_long)|uniprotkb:Thioredoxin-2(gene name synonym)|uniprotkb:Txn2(gene name)|psi-mi:Txn2(display_short)	psi-mi:prdx6_mouse(display_long)|uniprotkb:Lysophosphatidylcholine acyltransferase 5(gene name synonym)|uniprotkb:Glutathione-dependent peroxiredoxin(gene name synonym)|uniprotkb:Antioxidant protein 2(gene name synonym)|uniprotkb:1-Cys peroxiredoxin(gene name synonym)|uniprotkb:Acidic calcium-independent phospholipase A2(gene name synonym)|uniprotkb:Non-selenium glutathione peroxidase(gene name synonym)|uniprotkb:Prdx6(gene name)|psi-mi:Prdx6(display_short)|uniprotkb:Aop2(gene name synonym)|uniprotkb:Ltw4(gene name synonym)|uniprotkb:Prdx5(gene name synonym)	psi-mi:"MI:0096"(pull down)	Chasapis et al. (2019)	pubmed:31018154|imex:IM-28571	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26500426|imex:IM-28571-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	intact:EBI-8354432(chain-parent)	refseq:NP_031479.1|interpro:IPR000866(Alkyl hydroperoxide reductase/ Thiol specific antioxidant/ Mal allergen)|interpro:IPR024706|interpro:IPR019479|go:"GO:0000302"(response to reactive oxygen species)|go:"GO:0004601"(peroxidase activity)|go:"GO:0004602"(glutathione peroxidase activity)|go:"GO:0004623"(phospholipase A2 activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005764"(lysosome)|go:"GO:0005829"(cytosol)|go:"GO:0006979"(response to oxidative stress)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032060"(bleb assembly)|go:"GO:0042744"(hydrogen peroxide catabolic process)|go:"GO:0042802"(identical protein binding)|go:"GO:0045454"(cell redox homeostasis)|go:"GO:0046475"(glycerophospholipid catabolic process)|go:"GO:0047184"(1-acylglycerophosphocholine O-acyltransferase activity)|go:"GO:0047499"(calcium-independent phospholipase A2 activity)|go:"GO:0048026"(positive regulation of mRNA splicing, via spliceosome)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051920"(peroxiredoxin activity)|go:"GO:0098869"(cellular oxidant detoxification)|go:"GO:0102567"|go:"GO:0102568"|reactome:R-MMU-3299685|reactome:R-MMU-6798695|interpro:IPR013766(Thioredoxin domain)|mint:O08709|interpro:IPR036249	-	chain-seq-start:60|chain-seq-end:166	-	figure legend:ST1.8|comment:DTT-eluted fraction|dataset:Rare diseases - Interactions investigated in the context of Rare genetic disease|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2020/12/04	2020/12/21	rogid:mvYK6+YgIN/WuGLBCWqsqPLfDyQ10090	rogid:3Hnse2vkowtSGEobI2LJX6WrNl410090	rigid:n4xAXAOqYXh1CN68jXiWJ3spgS8	false	mutation:34-34	-	-	-	psi-mi:"MI:0082"(peptide massfingerprinting)	psi-mi:"MI:0082"(peptide massfingerprinting)
uniprotkb:P97493-PRO_0000034151	uniprotkb:P99029	intact:EBI-26567598	intact:EBI-2735704|uniprotkb:Q9QX45|uniprotkb:Q9QZ75|ensembl:ENSMUSP00000025904	psi-mi:p97493-pro_0000034151(display_long)|uniprotkb:Thioredoxin-2(gene name synonym)|uniprotkb:Txn2(gene name)|psi-mi:Txn2(display_short)	psi-mi:prdx5_mouse(display_long)|uniprotkb:Prdx5(gene name)|psi-mi:Prdx5(display_short)|uniprotkb:Prdx6(gene name synonym)|uniprotkb:Peroxiredoxin V(gene name synonym)|uniprotkb:Peroxisomal antioxidant enzyme(gene name synonym)|uniprotkb:PLP(gene name synonym)|uniprotkb:Thioredoxin peroxidase PMP20(gene name synonym)|uniprotkb:Antioxidant enzyme B166(gene name synonym)|uniprotkb:Liver tissue 2D-page spot 2D-0014IV(gene name synonym)|uniprotkb:Thioredoxin-dependent peroxiredoxin 5(gene name synonym)	psi-mi:"MI:0096"(pull down)	Chasapis et al. (2019)	pubmed:31018154|imex:IM-28571	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26500426|imex:IM-28571-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	intact:EBI-8354432(chain-parent)	refseq:NP_036151.1|ensembl:ENSMUSG00000024953(gene)|ensembl:ENSMUST00000025904(transcript)|go:"GO:0001016"(RNA polymerase III transcription regulatory region sequence-specific DNA binding)|go:"GO:0004601"(peroxidase activity)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005777"(peroxisome)|go:"GO:0005782"(peroxisomal matrix)|go:"GO:0005829"(cytosol)|go:"GO:0006979"(response to oxidative stress)|go:"GO:0008379"(thioredoxin peroxidase activity)|go:"GO:0016209"(antioxidant activity)|go:"GO:0016480"(negative regulation of transcription by RNA polymerase III)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0032967"(positive regulation of collagen biosynthetic process)|go:"GO:0034599"(cellular response to oxidative stress)|go:"GO:0034614"(cellular response to reactive oxygen species)|go:"GO:0042744"(hydrogen peroxide catabolic process)|go:"GO:0043027"(cysteine-type endopeptidase inhibitor activity involved in apoptotic process)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0045454"(cell redox homeostasis)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051354"(negative regulation of oxidoreductase activity)|go:"GO:0051920"(peroxiredoxin activity)|go:"GO:0060785"(regulation of apoptosis involved in tissue homeostasis)|go:"GO:0070995"(NADPH oxidation)|go:"GO:0072541"(peroxynitrite reductase activity)|go:"GO:2001057"(reactive nitrogen species metabolic process)|interpro:IPR013740(Redoxin)|interpro:IPR036249|interpro:IPR037944|mint:P99029|reactome:R-MMU-3299685|reactome:R-MMU-5628897|interpro:IPR013766(Thioredoxin domain)	-	chain-seq-start:60|chain-seq-end:166	-	figure legend:ST1.8|comment:DTT-eluted fraction|dataset:Rare diseases - Interactions investigated in the context of Rare genetic disease|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2020/12/04	2020/12/21	rogid:mvYK6+YgIN/WuGLBCWqsqPLfDyQ10090	rogid:uWS2EcAdupLmsVsQ6h1AV+vRffs10090	rigid:n4xAXAOqYXh1CN68jXiWJ3spgS8	false	mutation:34-34	-	-	-	psi-mi:"MI:0082"(peptide massfingerprinting)	psi-mi:"MI:0082"(peptide massfingerprinting)
uniprotkb:P97493-PRO_0000034151	uniprotkb:O08807	intact:EBI-26567598	intact:EBI-494652|uniprotkb:Q3U8E4|uniprotkb:B1AZS7|ensembl:ENSMUSP00000026328	psi-mi:p97493-pro_0000034151(display_long)|uniprotkb:Thioredoxin-2(gene name synonym)|uniprotkb:Txn2(gene name)|psi-mi:Txn2(display_short)	psi-mi:prdx4_mouse(display_long)|uniprotkb:Peroxiredoxin IV(gene name synonym)|uniprotkb:Thioredoxin peroxidase AO372(gene name synonym)|uniprotkb:Thioredoxin-dependent peroxide reductase A0372(gene name synonym)|uniprotkb:Antioxidant enzyme AOE372(gene name synonym)|uniprotkb:Thioredoxin-dependent peroxiredoxin 4(gene name synonym)|uniprotkb:Prdx4(gene name)|psi-mi:Prdx4(display_short)	psi-mi:"MI:0096"(pull down)	Chasapis et al. (2019)	pubmed:31018154|imex:IM-28571	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26500426|imex:IM-28571-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	intact:EBI-8354432(chain-parent)	refseq:NP_058044.1|refseq:NP_001300640.1|dip:DIP-34137N|ensembl:ENSMUSG00000025289(gene)|ensembl:ENSMUST00000026328(transcript)|go:"GO:0004601"(peroxidase activity)|go:"GO:0005615"(extracellular space)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005790"(smooth endoplasmic reticulum)|go:"GO:0005829"(cytosol)|go:"GO:0006979"(response to oxidative stress)|go:"GO:0007283"(spermatogenesis)|go:"GO:0008584"(male gonad development)|go:"GO:0018401"(peptidyl-proline hydroxylation to 4-hydroxy-L-proline)|go:"GO:0022417"(protein maturation by protein folding)|go:"GO:0030198"(extracellular matrix organization)|go:"GO:0042802"(identical protein binding)|go:"GO:0045454"(cell redox homeostasis)|go:"GO:0051920"(peroxiredoxin activity)|go:"GO:0072593"(reactive oxygen species metabolic process)|go:"GO:2000255"(negative regulation of male germ cell proliferation)|interpro:IPR000866(Alkyl hydroperoxide reductase/ Thiol specific antioxidant/ Mal allergen)|interpro:IPR013766(Thioredoxin domain)|interpro:IPR019479|interpro:IPR036249|mint:O08807|rcsb pdb:3VWU|rcsb pdb:3VWV|rcsb pdb:3W8J|rcsb pdb:3WGX|reactome:R-MMU-6798695	-	chain-seq-start:60|chain-seq-end:166	-	figure legend:ST1.8|comment:DTT-eluted fraction|dataset:Rare diseases - Interactions investigated in the context of Rare genetic disease|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2020/12/04	2020/12/21	rogid:mvYK6+YgIN/WuGLBCWqsqPLfDyQ10090	rogid:86EzEedrO6v5Z2dnSB2fSPaV2hc10090	rigid:n4xAXAOqYXh1CN68jXiWJ3spgS8	false	mutation:34-34	-	-	-	psi-mi:"MI:0082"(peptide massfingerprinting)	psi-mi:"MI:0082"(peptide massfingerprinting)
uniprotkb:P97493-PRO_0000034151	uniprotkb:Q61171	intact:EBI-26567598	intact:EBI-444957|uniprotkb:O88376|uniprotkb:Q60796|uniprotkb:Q9CWJ4|uniprotkb:Q9DB49|ensembl:ENSMUSP00000005292|ensembl:ENSMUSP00000105355|ensembl:ENSMUSP00000105356|ensembl:ENSMUSP00000126451	psi-mi:p97493-pro_0000034151(display_long)|uniprotkb:Thioredoxin-2(gene name synonym)|uniprotkb:Txn2(gene name)|psi-mi:Txn2(display_short)	psi-mi:prdx2_mouse(display_long)|uniprotkb:Thioredoxin-dependent peroxiredoxin 2(gene name synonym)|uniprotkb:Thioredoxin peroxidase 1(gene name synonym)|uniprotkb:Thioredoxin-dependent peroxide reductase 1(gene name synonym)|uniprotkb:Thiol-specific antioxidant protein(gene name synonym)|uniprotkb:Prdx2(gene name)|psi-mi:Prdx2(display_short)|uniprotkb:Tdpx1(gene name synonym)|uniprotkb:Tpx(gene name synonym)	psi-mi:"MI:0096"(pull down)	Chasapis et al. (2019)	pubmed:31018154|imex:IM-28571	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26500426|imex:IM-28571-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	intact:EBI-8354432(chain-parent)	refseq:NP_035693.3|go:"GO:0042098"(T cell proliferation)|go:"GO:0042743"(hydrogen peroxide metabolic process)|go:"GO:0042744"(hydrogen peroxide catabolic process)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0043209"(myelin sheath)|go:"GO:0043410"(positive regulation of MAPK cascade)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0045321"(leukocyte activation)|go:"GO:0045454"(cell redox homeostasis)|go:"GO:0045581"(negative regulation of T cell differentiation)|go:"GO:0048538"(thymus development)|go:"GO:0048872"(homeostasis of number of cells)|go:"GO:2001237"(negative regulation of extrinsic apoptotic signaling pathway)|go:"GO:2001240"(negative regulation of extrinsic apoptotic signaling pathway in absence of ligand)|interpro:IPR000866(Alkyl hydroperoxide reductase/ Thiol specific antioxidant/ Mal allergen)|interpro:IPR013766(Thioredoxin domain)|interpro:IPR019479|interpro:IPR024706|interpro:IPR036249|mint:Q61171|reactome:R-MMU-3299685|reactome:R-MMU-5628897|go:"GO:0034599"(cellular response to oxidative stress)|refseq:NP_001304314.1|ensembl:ENSMUSG00000005161(gene)|ensembl:ENSMUST00000005292(transcript)|ensembl:ENSMUST00000109733(transcript)|ensembl:ENSMUST00000109734(transcript)|ensembl:ENSMUST00000164807(transcript)|go:"GO:0002357"(defense response to tumor cell)|go:"GO:0002536"(respiratory burst involved in inflammatory response)|go:"GO:0004601"(peroxidase activity)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0006979"(response to oxidative stress)|go:"GO:0008379"(thioredoxin peroxidase activity)|go:"GO:0008430"(selenium binding)|go:"GO:0010310"(regulation of hydrogen peroxide metabolic process)|go:"GO:0016209"(antioxidant activity)|go:"GO:0019430"(removal of superoxide radicals)|go:"GO:0030194"(positive regulation of blood coagulation)|go:"GO:0031665"(negative regulation of lipopolysaccharide-mediated signaling pathway)|go:"GO:0032088"(negative regulation of NF-kappaB transcription factor activity)|go:"GO:0032496"(response to lipopolysaccharide)	-	chain-seq-start:60|chain-seq-end:166	-	figure legend:ST1.8|comment:DTT-eluted fraction|dataset:Rare diseases - Interactions investigated in the context of Rare genetic disease|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2020/12/04	2020/12/21	rogid:mvYK6+YgIN/WuGLBCWqsqPLfDyQ10090	rogid:P1NxwIOnv1n4sNzQWtFjy2znSbA10090	rigid:n4xAXAOqYXh1CN68jXiWJ3spgS8	false	mutation:34-34	-	-	-	psi-mi:"MI:0082"(peptide massfingerprinting)	psi-mi:"MI:0082"(peptide massfingerprinting)
uniprotkb:P97493-PRO_0000034151	uniprotkb:P35700	intact:EBI-26567598	intact:EBI-444948|uniprotkb:Q3UBV4|uniprotkb:Q9CWI2|ensembl:ENSMUSP00000102078|ensembl:ENSMUSP00000114159	psi-mi:p97493-pro_0000034151(display_long)|uniprotkb:Thioredoxin-2(gene name synonym)|uniprotkb:Txn2(gene name)|psi-mi:Txn2(display_short)	psi-mi:prdx1_mouse(display_long)|uniprotkb:Thioredoxin-dependent peroxiredoxin 1(gene name synonym)|uniprotkb:Thioredoxin-dependent peroxide reductase 2(gene name synonym)|uniprotkb:Osteoblast-specific factor 3(gene name synonym)|uniprotkb:Macrophage 23 kDa stress protein(gene name synonym)|uniprotkb:Thioredoxin peroxidase 2(gene name synonym)|uniprotkb:Prdx1(gene name)|psi-mi:Prdx1(display_short)|uniprotkb:Msp23(gene name synonym)|uniprotkb:Paga(gene name synonym)|uniprotkb:Tdpx2(gene name synonym)	psi-mi:"MI:0096"(pull down)	Chasapis et al. (2019)	pubmed:31018154|imex:IM-28571	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26500426|imex:IM-28571-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	intact:EBI-8354432(chain-parent)	refseq:NP_035164.1|ensembl:ENSMUST00000135573(transcript)|go:"GO:0000302"(response to reactive oxygen species)|go:"GO:0000791"(euchromatin)|go:"GO:0004601"(peroxidase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0005782"(peroxisomal matrix)|go:"GO:0005829"(cytosol)|go:"GO:0006979"(response to oxidative stress)|go:"GO:0008283"(cell population proliferation)|go:"GO:0008379"(thioredoxin peroxidase activity)|go:"GO:0019430"(removal of superoxide radicals)|go:"GO:0020037"(heme binding)|go:"GO:0030101"(natural killer cell activation)|go:"GO:0032872"(regulation of stress-activated MAPK cascade)|go:"GO:0034101"(erythrocyte homeostasis)|go:"GO:0042267"(natural killer cell mediated cytotoxicity)|go:"GO:0042744"(hydrogen peroxide catabolic process)|go:"GO:0042802"(identical protein binding)|go:"GO:0043209"(myelin sheath)|go:"GO:0045321"(leukocyte activation)|go:"GO:0045454"(cell redox homeostasis)|go:"GO:0051920"(peroxiredoxin activity)|go:"GO:1901222"(regulation of NIK/NF-kappaB signaling)|interpro:IPR000866(Alkyl hydroperoxide reductase/ Thiol specific antioxidant/ Mal allergen)|interpro:IPR013766(Thioredoxin domain)|interpro:IPR019479|interpro:IPR024706|interpro:IPR036249|mint:P35700|reactome:R-MMU-3299685|reactome:R-MMU-5628897|ensembl:ENSMUST00000106470(transcript)|ensembl:ENSMUSG00000028691(gene)	-	chain-seq-start:60|chain-seq-end:166	-	figure legend:ST1.8|comment:DTT-eluted fraction|dataset:Rare diseases - Interactions investigated in the context of Rare genetic disease|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2020/12/04	2020/12/21	rogid:mvYK6+YgIN/WuGLBCWqsqPLfDyQ10090	rogid:xOppWev1GtpILoJ1rY+tSPoymVU10090	rigid:n4xAXAOqYXh1CN68jXiWJ3spgS8	false	mutation:34-34	-	-	-	psi-mi:"MI:0082"(peptide massfingerprinting)	psi-mi:"MI:0082"(peptide massfingerprinting)
uniprotkb:P97493-PRO_0000034151	uniprotkb:Q3TW96	intact:EBI-26567598	intact:EBI-26500565|ensembl:ENSMUSP00000099989|uniprotkb:A1L3D3|uniprotkb:Q6KAP8|uniprotkb:Q6NVB6|uniprotkb:Q80XP4	psi-mi:p97493-pro_0000034151(display_long)|uniprotkb:Thioredoxin-2(gene name synonym)|uniprotkb:Txn2(gene name)|psi-mi:Txn2(display_short)	psi-mi:uap1l_mouse(display_long)|uniprotkb:Uap1l1(gene name)|psi-mi:Uap1l1(display_short)	psi-mi:"MI:0096"(pull down)	Chasapis et al. (2019)	pubmed:31018154|imex:IM-28571	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26500426|imex:IM-28571-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	intact:EBI-8354432(chain-parent)	ensembl:ENSMUSG00000026956(gene)|ensembl:ENSMUST00000102925(transcript)|go:"GO:0003977"(UDP-N-acetylglucosamine diphosphorylase activity)|go:"GO:0006048"(UDP-N-acetylglucosamine biosynthetic process)|interpro:IPR002618(UTP--glucose-1-phosphate uridylyltransferase)|interpro:IPR029044|interpro:IPR039741|mint:Q3TW96|refseq:NP_001028465.1	-	chain-seq-start:60|chain-seq-end:166	-	figure legend:ST1.8|comment:DTT-eluted fraction|dataset:Rare diseases - Interactions investigated in the context of Rare genetic disease|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2020/12/04	2020/12/21	rogid:mvYK6+YgIN/WuGLBCWqsqPLfDyQ10090	rogid:Az6O+UDuSDAnQe5QCYgwDOzg2Ko10090	rigid:n4xAXAOqYXh1CN68jXiWJ3spgS8	false	mutation:34-34	-	-	-	psi-mi:"MI:0082"(peptide massfingerprinting)	psi-mi:"MI:0082"(peptide massfingerprinting)
uniprotkb:P97493-PRO_0000034151	uniprotkb:Q8CAQ8	intact:EBI-26567598	intact:EBI-776087|uniprotkb:Q66JS4|uniprotkb:Q7TNE2|uniprotkb:Q8C7V1|uniprotkb:Q8CCI0|uniprotkb:Q8CDA8|uniprotkb:Q9D9F6|ensembl:ENSMUSP00000066181	psi-mi:p97493-pro_0000034151(display_long)|uniprotkb:Thioredoxin-2(gene name synonym)|uniprotkb:Txn2(gene name)|psi-mi:Txn2(display_short)	psi-mi:mic60_mouse(display_long)|uniprotkb:Mitofilin(gene name synonym)|uniprotkb:Immt(gene name)|psi-mi:Immt(display_short)|uniprotkb:Mic60(gene name synonym)|uniprotkb:Mitochondrial inner membrane protein(gene name synonym)	psi-mi:"MI:0096"(pull down)	Chasapis et al. (2019)	pubmed:31018154|imex:IM-28571	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26500426|imex:IM-28571-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	intact:EBI-8354432(chain-parent)	refseq:NP_083949.2|refseq:NP_001240617.1|refseq:NP_001240610.1|refseq:NP_001240616.1|dip:DIP-32050N|ensembl:ENSMUSG00000052337(gene)|ensembl:ENSMUST00000064062(transcript)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|mint:Q8CAQ8|go:"GO:0005758"(mitochondrial intermembrane space)|go:"GO:0042407"(cristae formation)|go:"GO:0043209"(myelin sheath)|go:"GO:0051560"(mitochondrial calcium ion homeostasis)|go:"GO:0061617"(MICOS complex)|interpro:IPR019133	-	chain-seq-start:60|chain-seq-end:166	-	figure legend:ST1.8|comment:DTT-eluted fraction|dataset:Rare diseases - Interactions investigated in the context of Rare genetic disease|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2020/12/04	2020/12/21	rogid:mvYK6+YgIN/WuGLBCWqsqPLfDyQ10090	rogid:fW23bvuLqjLn5wIOu6ycDsh7O1k10090	rigid:n4xAXAOqYXh1CN68jXiWJ3spgS8	false	mutation:34-34	-	-	-	psi-mi:"MI:0082"(peptide massfingerprinting)	psi-mi:"MI:0082"(peptide massfingerprinting)
uniprotkb:P97493-PRO_0000034151	uniprotkb:P61979	intact:EBI-26567598	intact:EBI-299907|ensembl:ENSMUSP00000039269|uniprotkb:Q07244|uniprotkb:Q15671|uniprotkb:Q60577|uniprotkb:Q8BGQ8|uniprotkb:Q922Y7|uniprotkb:Q96J62	psi-mi:p97493-pro_0000034151(display_long)|uniprotkb:Thioredoxin-2(gene name synonym)|uniprotkb:Txn2(gene name)|psi-mi:Txn2(display_short)	psi-mi:hnrpk_mouse(display_long)|uniprotkb:Hnrnpk(gene name)|psi-mi:Hnrnpk(display_short)|uniprotkb:Hnrpk(gene name synonym)	psi-mi:"MI:0096"(pull down)	Chasapis et al. (2019)	pubmed:31018154|imex:IM-28571	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26500426|imex:IM-28571-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	intact:EBI-8354432(chain-parent)	ensembl:ENSMUST00000043269(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000987"(cis-regulatory region sequence-specific DNA binding)|go:"GO:0001541"(ovarian follicle development)|go:"GO:0002102"(podosome)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0003730"(mRNA 3'-UTR binding)|go:"GO:0005521"(lamin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0005938"(cell cortex)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006397"(mRNA processing)|go:"GO:0008380"(RNA splicing)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0010494"(cytoplasmic stress granule)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0010976"(positive regulation of neuron projection development)|go:"GO:0010988"(regulation of low-density lipoprotein particle clearance)|go:"GO:0014069"(postsynaptic density)|go:"GO:0019904"(protein domain specific binding)|ensembl:ENSMUSG00000021546(gene)|go:"GO:0031072"(heat shock protein binding)|go:"GO:0032091"(negative regulation of protein binding)|go:"GO:0032869"(cellular response to insulin stimulus)|go:"GO:0032993"(protein-DNA complex)|go:"GO:0033120"(positive regulation of RNA splicing)|go:"GO:0042802"(identical protein binding)|go:"GO:0042805"(actinin binding)|go:"GO:0043021"(ribonucleoprotein complex binding)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043197"(dendritic spine)|go:"GO:0043679"(axon terminus)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048024"(regulation of mRNA splicing, via spliceosome)|go:"GO:0048025"(negative regulation of mRNA splicing, via spliceosome)|go:"GO:0021987"(cerebral cortex development)|go:"GO:0048260"(positive regulation of receptor-mediated endocytosis)|go:"GO:0050804"(modulation of chemical synaptic transmission)|go:"GO:0030628"(pre-mRNA 3'-splice site binding)|go:"GO:0050806"(positive regulation of synaptic transmission)|go:"GO:1905599"(positive regulation of low-density lipoprotein receptor activity)|go:"GO:1990715"(mRNA CDS binding)|go:"GO:1990829"(C-rich single-stranded DNA binding)|go:"GO:2000010"(positive regulation of protein localization to cell surface)|go:"GO:2000173"(negative regulation of branching morphogenesis of a nerve)|interpro:IPR004087(K Homology)|go:"GO:0051117"(ATPase binding)|go:"GO:0060999"(positive regulation of dendritic spine development)|interpro:IPR004088(K Homology, type 1)|interpro:IPR012987(ROK, N-terminal)|interpro:IPR033090|interpro:IPR036612|mint:P61979|reactome:R-MMU-4570464|reactome:R-MMU-72163|reactome:R-MMU-72203|go:"GO:0071013"(catalytic step 2 spliceosome)|go:"GO:0090129"(positive regulation of synapse maturation)|go:"GO:0098794"(postsynapse)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099175"(regulation of postsynapse organization)|go:"GO:1900273"(positive regulation of long-term synaptic potentiation)|go:"GO:1902165"(regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator)|go:"GO:1903861"(positive regulation of dendrite extension)|go:"GO:1904322"(cellular response to forskolin)|refseq:NP_001288269.1|refseq:NP_001288270.1|refseq:NP_001288272.1|refseq:NP_001288273.1|refseq:NP_001288274.1|refseq:XP_017170884.1|refseq:XP_017170885.1|refseq:NP_079555.1|refseq:XP_006517166.1|refseq:XP_006517167.1	-	chain-seq-start:60|chain-seq-end:166	-	figure legend:ST1.8|comment:DTT-eluted fraction|dataset:Rare diseases - Interactions investigated in the context of Rare genetic disease|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2020/12/04	2020/12/21	rogid:mvYK6+YgIN/WuGLBCWqsqPLfDyQ10090	rogid:YZQD5JJkHPUMtZ4XUA9fQkNfXzc10090	rigid:n4xAXAOqYXh1CN68jXiWJ3spgS8	false	mutation:34-34	-	-	-	psi-mi:"MI:0082"(peptide massfingerprinting)	psi-mi:"MI:0082"(peptide massfingerprinting)
uniprotkb:P97493-PRO_0000034151	uniprotkb:Q8BG05	intact:EBI-26567598	intact:EBI-2735601|uniprotkb:Q8BHF8|ensembl:ENSMUSP00000088298|ensembl:ENSMUSP00000107595	psi-mi:p97493-pro_0000034151(display_long)|uniprotkb:Thioredoxin-2(gene name synonym)|uniprotkb:Txn2(gene name)|psi-mi:Txn2(display_short)	psi-mi:roa3_mouse(display_long)|uniprotkb:Hnrnpa3(gene name)|psi-mi:Hnrnpa3(display_short)|uniprotkb:Hnrpa3(gene name synonym)	psi-mi:"MI:0096"(pull down)	Chasapis et al. (2019)	pubmed:31018154|imex:IM-28571	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26500426|imex:IM-28571-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	intact:EBI-8354432(chain-parent)	refseq:NP_444493.1|refseq:NP_666242.2|refseq:NP_932758.1|ensembl:ENSMUSG00000059005(gene)|ensembl:ENSMUST00000090792(transcript)|ensembl:ENSMUST00000111964(transcript)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006397"(mRNA processing)|go:"GO:0008380"(RNA splicing)|go:"GO:0014069"(postsynaptic density)|go:"GO:0035770"(ribonucleoprotein granule)|go:"GO:0043005"(neuron projection)|go:"GO:0051028"(mRNA transport)|go:"GO:0051033"(RNA transmembrane transporter activity)|go:"GO:0071013"(catalytic step 2 spliceosome)|go:"GO:1990124"(messenger ribonucleoprotein complex)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR034513|interpro:IPR034516|interpro:IPR035979|mint:Q8BG05|reactome:R-MMU-72163|reactome:R-MMU-72203|refseq:XP_011237818.1	-	chain-seq-start:60|chain-seq-end:166	-	figure legend:ST1.8|comment:DTT-eluted fraction|dataset:Rare diseases - Interactions investigated in the context of Rare genetic disease|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2020/12/04	2020/12/21	rogid:mvYK6+YgIN/WuGLBCWqsqPLfDyQ10090	rogid:KcZjXvHON9QZSqHWi4nWSDz/HtE10090	rigid:n4xAXAOqYXh1CN68jXiWJ3spgS8	false	mutation:34-34	-	-	-	psi-mi:"MI:0082"(peptide massfingerprinting)	psi-mi:"MI:0082"(peptide massfingerprinting)
uniprotkb:P97493-PRO_0000034151	uniprotkb:P02089	intact:EBI-26567598	intact:EBI-494213|uniprotkb:Q5D0E8	psi-mi:p97493-pro_0000034151(display_long)|uniprotkb:Thioredoxin-2(gene name synonym)|uniprotkb:Txn2(gene name)|psi-mi:Txn2(display_short)	psi-mi:hbb2_mouse(display_long)|uniprotkb:Hemoglobin beta-2 chain(gene name synonym)|uniprotkb:Beta-2-globin(gene name synonym)|uniprotkb:Hemoglobin beta-minor chain(gene name synonym)|uniprotkb:Hbb-b2(gene name)|psi-mi:Hbb-b2(display_short)	psi-mi:"MI:0096"(pull down)	Chasapis et al. (2019)	pubmed:31018154|imex:IM-28571	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26500426|imex:IM-28571-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	intact:EBI-8354432(chain-parent)	interpro:IPR009050(Globin-like)|interpro:IPR000971(Globin, subset)|interpro:IPR002337(Haemoglobin, beta)|refseq:NP_058652.1|interpro:IPR012292(Globin)|go:"GO:0005344"(oxygen carrier activity)|go:"GO:0005833"(hemoglobin complex)|go:"GO:0019825"(oxygen binding)|go:"GO:0020037"(heme binding)|go:"GO:0031721"(hemoglobin alpha binding)|go:"GO:0031838"(haptoglobin-hemoglobin complex)|go:"GO:0042744"(hydrogen peroxide catabolic process)|go:"GO:0043177"(organic acid binding)|go:"GO:0045639"(positive regulation of myeloid cell differentiation)|go:"GO:0045646"(regulation of erythrocyte differentiation)|go:"GO:0046872"(metal ion binding)|go:"GO:0048821"(erythrocyte development)|go:"GO:0098869"(cellular oxidant detoxification)|rcsb pdb:1FNE|rcsb pdb:1FNG|rcsb pdb:1I3R|mint:P02089	-	chain-seq-start:60|chain-seq-end:166	-	figure legend:ST1.8|comment:DTT-eluted fraction|dataset:Rare diseases - Interactions investigated in the context of Rare genetic disease|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2020/12/04	2020/12/21	rogid:mvYK6+YgIN/WuGLBCWqsqPLfDyQ10090	rogid:5t7MUKklDto4E5kgtOvSP8i82vU10090	rigid:n4xAXAOqYXh1CN68jXiWJ3spgS8	false	mutation:34-34	-	-	-	psi-mi:"MI:0082"(peptide massfingerprinting)	psi-mi:"MI:0082"(peptide massfingerprinting)
uniprotkb:P97493-PRO_0000034151	uniprotkb:P02088	intact:EBI-26567598	intact:EBI-494201|uniprotkb:Q54AI0|uniprotkb:Q91V86|uniprotkb:Q9CRZ2|uniprotkb:Q9CXH5|uniprotkb:Q9CY12|uniprotkb:Q9CY54|uniprotkb:Q9R0S6	psi-mi:p97493-pro_0000034151(display_long)|uniprotkb:Thioredoxin-2(gene name synonym)|uniprotkb:Txn2(gene name)|psi-mi:Txn2(display_short)	psi-mi:hbb1_mouse(display_long)|uniprotkb:Hemoglobin beta-1 chain(gene name synonym)|uniprotkb:Beta-1-globin(gene name synonym)|uniprotkb:Hemoglobin beta-major chain(gene name synonym)|uniprotkb:Hbb-b1(gene name)|psi-mi:Hbb-b1(display_short)	psi-mi:"MI:0096"(pull down)	Chasapis et al. (2019)	pubmed:31018154|imex:IM-28571	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26500426|imex:IM-28571-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	intact:EBI-8354432(chain-parent)	refseq:NP_001188320.1|refseq:NP_032246.2|interpro:IPR009050(Globin-like)|interpro:IPR000971(Globin, subset)|interpro:IPR002337(Haemoglobin, beta)|interpro:IPR012292(Globin)|refseq:NP_001265090.1|go:"GO:0005344"(oxygen carrier activity)|go:"GO:0005833"(hemoglobin complex)|go:"GO:0010999"(regulation of eIF2 alpha phosphorylation by heme)|go:"GO:0015671"(oxygen transport)|go:"GO:0019825"(oxygen binding)|go:"GO:0020037"(heme binding)|go:"GO:0030097"(hemopoiesis)|go:"GO:0031721"(hemoglobin alpha binding)|go:"GO:0031838"(haptoglobin-hemoglobin complex)|go:"GO:0042744"(hydrogen peroxide catabolic process)|go:"GO:0043177"(organic acid binding)|go:"GO:0043209"(myelin sheath)|go:"GO:0046872"(metal ion binding)|go:"GO:0048821"(erythrocyte development)|go:"GO:0098869"(cellular oxidant detoxification)|rcsb pdb:1JEB|rcsb pdb:3HRW|mint:P02088	-	chain-seq-start:60|chain-seq-end:166	-	figure legend:ST1.8|comment:DTT-eluted fraction|dataset:Rare diseases - Interactions investigated in the context of Rare genetic disease|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2020/12/04	2020/12/21	rogid:mvYK6+YgIN/WuGLBCWqsqPLfDyQ10090	rogid:/W1Bo3qzhsm3Fzb/joImMwzE/Dg10090	rigid:n4xAXAOqYXh1CN68jXiWJ3spgS8	false	mutation:34-34	-	-	-	psi-mi:"MI:0082"(peptide massfingerprinting)	psi-mi:"MI:0082"(peptide massfingerprinting)
uniprotkb:P97493-PRO_0000034151	uniprotkb:P70441	intact:EBI-26567598	intact:EBI-1184085|uniprotkb:Q8BYD8|ensembl:ENSMUSP00000021077	psi-mi:p97493-pro_0000034151(display_long)|uniprotkb:Thioredoxin-2(gene name synonym)|uniprotkb:Txn2(gene name)|psi-mi:Txn2(display_short)	psi-mi:nhrf1_mouse(display_long)|uniprotkb:Slc9a3r1(gene name)|psi-mi:Slc9a3r1(display_short)|uniprotkb:Nherf(gene name synonym)|uniprotkb:Nherf1(gene name synonym)|uniprotkb:Ezrin-radixin-moesin-binding phosphoprotein 50(gene name synonym)|uniprotkb:"Regulatory cofactor of Na(+)/H(+) exchanger"(gene name synonym)|uniprotkb:Sodium-hydrogen exchanger regulatory factor 1(gene name synonym)|uniprotkb:Solute carrier family 9 isoform A3 regulatory factor 1(gene name synonym)	psi-mi:"MI:0096"(pull down)	Chasapis et al. (2019)	pubmed:31018154|imex:IM-28571	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26500426|imex:IM-28571-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	intact:EBI-8354432(chain-parent)	refseq:NP_036160.1|ensembl:ENSMUSG00000020733(gene)|ensembl:ENSMUST00000021077(transcript)|go:"GO:0001726"(ruffle)|go:"GO:0003096"(renal sodium ion transport)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0005902"(microvillus)|go:"GO:0007009"(plasma membrane organization)|go:"GO:0007097"(nuclear migration)|go:"GO:0007191"(adenylate cyclase-activating dopamine receptor signaling pathway)|go:"GO:0007605"(sensory perception of sound)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0008360"(regulation of cell shape)|go:"GO:0008361"(regulation of cell size)|go:"GO:0010642"(negative regulation of platelet-derived growth factor receptor signaling pathway)|go:"GO:0010766"(negative regulation of sodium ion transport)|go:"GO:0012505"(endomembrane system)|go:"GO:0014067"(negative regulation of phosphatidylinositol 3-kinase signaling)|go:"GO:0015185"(gamma-aminobutyric acid transmembrane transporter activity)|go:"GO:0016020"(membrane)|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0017081"(chloride channel regulator activity)|go:"GO:0019902"(phosphatase binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0019933"(cAMP-mediated signaling)|go:"GO:0022612"(gland morphogenesis)|go:"GO:0030033"(microvillus assembly)|go:"GO:0030036"(actin cytoskeleton organization)|go:"GO:0030165"(PDZ domain binding)|go:"GO:0030175"(filopodium)|go:"GO:0030336"(negative regulation of cell migration)|go:"GO:0030643"(cellular phosphate ion homeostasis)|go:"GO:0031526"(brush border membrane)|go:"GO:0031528"(microvillus membrane)|go:"GO:0031698"(beta-2 adrenergic receptor binding)|go:"GO:0031799"(type 2 metabotropic glutamate receptor binding)|go:"GO:0031800"(type 3 metabotropic glutamate receptor binding)|go:"GO:0032420"(stereocilium)|go:"GO:0032426"(stereocilium tip)|go:"GO:0032782"(bile acid secretion)|go:"GO:0034613"(cellular protein localization)|go:"GO:0034635"(glutathione transport)|go:"GO:0034767"(positive regulation of ion transmembrane transport)|go:"GO:0032416"("negative regulation of sodium:proton antiporter activity")|go:"GO:0043495"(protein-membrane adaptor activity)|go:"GO:0043621"(protein self-association)|go:"GO:0044062"(regulation of excretion)|go:"GO:0044782"(cilium organization)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045121"(membrane raft)|go:"GO:0045159"(myosin II binding)|go:"GO:0045177"(apical part of cell)|go:"GO:0045198"(establishment of epithelial cell apical/basal polarity)|go:"GO:0045199"(maintenance of epithelial cell apical/basal polarity)|go:"GO:0045859"(regulation of protein kinase activity)|go:"GO:0045930"(negative regulation of mitotic cell cycle)|go:"GO:0047485"(protein N-terminus binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0050780"(dopamine receptor binding)|go:"GO:0051683"(establishment of Golgi localization)|go:"GO:0051898"(negative regulation of protein kinase B signaling)|go:"GO:0051939"(gamma-aminobutyric acid import)|go:"GO:0060088"(auditory receptor cell stereocilium organization)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0060158"(phospholipase C-activating dopamine receptor signaling pathway)|go:"GO:0070293"(renal absorption)|go:"GO:0070373"(negative regulation of ERK1 and ERK2 cascade)|go:"GO:0070851"(growth factor receptor binding)|go:"GO:0071944"(cell periphery)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:0090660"(cerebrospinal fluid circulation)|go:"GO:0097225"(sperm midpiece)|go:"GO:0097291"(renal phosphate ion absorption)|go:"GO:0098739"(import across plasma membrane)|go:"GO:0098797"(plasma membrane protein complex)|go:"GO:2000146"(negative regulation of cell motility)|go:"GO:2001244"(positive regulation of intrinsic apoptotic signaling pathway)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR015098(EBP50, C-terminal)|interpro:IPR017300("Na(+)/H(+) exchange regulatory cofactor NHE-RF")|interpro:IPR031199|interpro:IPR036034|mint:P70441	-	chain-seq-start:60|chain-seq-end:166	-	figure legend:ST1.8|comment:DTT-eluted fraction|dataset:Rare diseases - Interactions investigated in the context of Rare genetic disease|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2020/12/04	2020/12/21	rogid:mvYK6+YgIN/WuGLBCWqsqPLfDyQ10090	rogid:0Tz5KKGiYYEbcyP2lx4RrXUc76o10090	rigid:n4xAXAOqYXh1CN68jXiWJ3spgS8	false	mutation:34-34	-	-	-	psi-mi:"MI:0082"(peptide massfingerprinting)	psi-mi:"MI:0082"(peptide massfingerprinting)
uniprotkb:P97493-PRO_0000034151	uniprotkb:Q78JT3	intact:EBI-26567598	intact:EBI-26500534|ensembl:ENSMUSP00000000687|uniprotkb:Q52L88	psi-mi:p97493-pro_0000034151(display_long)|uniprotkb:Thioredoxin-2(gene name synonym)|uniprotkb:Txn2(gene name)|psi-mi:Txn2(display_short)	psi-mi:3hao_mouse(display_long)|uniprotkb:Haao(gene name)|psi-mi:Haao(display_short)|uniprotkb:3-hydroxyanthranilate oxygenase(gene name synonym)|uniprotkb:3-hydroxyanthranilic acid dioxygenase(gene name synonym)	psi-mi:"MI:0096"(pull down)	Chasapis et al. (2019)	pubmed:31018154|imex:IM-28571	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26500426|imex:IM-28571-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	intact:EBI-8354432(chain-parent)	ensembl:ENSMUSG00000000673(gene)|ensembl:ENSMUST00000000687(transcript)|go:"GO:0000334"(3-hydroxyanthranilate 3,4-dioxygenase activity)|go:"GO:0005506"(iron ion binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006569"(tryptophan catabolic process)|go:"GO:0008198"(ferrous iron binding)|go:"GO:0009435"(NAD biosynthetic process)|go:"GO:0010043"(response to zinc ion)|go:"GO:0019805"(quinolinate biosynthetic process)|go:"GO:0019825"(oxygen binding)|go:"GO:0031966"(mitochondrial membrane)|go:"GO:0034354"('de novo' NAD biosynthetic process from tryptophan)|go:"GO:0043420"(anthranilate metabolic process)|go:"GO:0046686"(response to cadmium ion)|go:"GO:0046874"(quinolinate metabolic process)|go:"GO:0070050"(neuron cellular homeostasis)|interpro:IPR010329(3-hydroxyanthranilic acid dioxygenase)|interpro:IPR011051(Cupin, RmlC-type)|interpro:IPR014710(RmlC-like jelly roll fold)|interpro:IPR016700(3-hydroxyanthranilate 3, 4-dioxygenase, metazoan)|mint:Q78JT3|reactome:R-MMU-71240|refseq:NP_079601.1|refseq:XP_006523526.1	-	chain-seq-start:60|chain-seq-end:166	-	figure legend:ST1.8|comment:DTT-eluted fraction|dataset:Rare diseases - Interactions investigated in the context of Rare genetic disease|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2020/12/04	2020/12/21	rogid:mvYK6+YgIN/WuGLBCWqsqPLfDyQ10090	rogid:D2kNH+K7kSo2bC1s6QLAHVtoDow10090	rigid:n4xAXAOqYXh1CN68jXiWJ3spgS8	false	mutation:34-34	-	-	-	psi-mi:"MI:0082"(peptide massfingerprinting)	psi-mi:"MI:0082"(peptide massfingerprinting)
uniprotkb:P97493-PRO_0000034151	uniprotkb:Q8BFR5	intact:EBI-26567598	intact:EBI-299611|ensembl:ENSMUSP00000095656|uniprotkb:Q497E7|uniprotkb:Q6P919	psi-mi:p97493-pro_0000034151(display_long)|uniprotkb:Thioredoxin-2(gene name synonym)|uniprotkb:Txn2(gene name)|psi-mi:Txn2(display_short)	psi-mi:eftu_mouse(display_long)|uniprotkb:Tufm(gene name)|psi-mi:Tufm(display_short)	psi-mi:"MI:0096"(pull down)	Chasapis et al. (2019)	pubmed:31018154|imex:IM-28571	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26500426|imex:IM-28571-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	intact:EBI-8354432(chain-parent)	ensembl:ENSMUSG00000073838(gene)|ensembl:ENSMUST00000098048(transcript)|go:"GO:0003746"(translation elongation factor activity)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0006414"(translational elongation)|go:"GO:0043209"(myelin sheath)|go:"GO:0045202"(synapse)|go:"GO:0045471"(response to ethanol)|go:"GO:0070125"(mitochondrial translational elongation)|interpro:IPR000795(Protein synthesis factor, GTP-binding)|interpro:IPR004160(Translation elongation factor EFTu/EF1A, C-terminal)|interpro:IPR004161(Translation elongation factor EFTu/EF1A, domain 2)|interpro:IPR004541(Translation elongation factor EFTu/EF1A, bacterial and organelle)|interpro:IPR009000(Translation elongation and initiation factors/Ribosomal, beta-barrel)|interpro:IPR009001(Translation elongation factor EF1A/initiation factor IF2gamma, C-terminal)|interpro:IPR027417|interpro:IPR031157|interpro:IPR033720|interpro:IPR041709|mint:Q8BFR5|go:"GO:0042645"(mitochondrial nucleoid)|refseq:NP_001157185.1|refseq:NP_766333.1	-	chain-seq-start:60|chain-seq-end:166	-	figure legend:ST1.8|comment:DTT-eluted fraction|dataset:Rare diseases - Interactions investigated in the context of Rare genetic disease|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2020/12/04	2020/12/21	rogid:mvYK6+YgIN/WuGLBCWqsqPLfDyQ10090	rogid:ax4f72KkJMxjxZD3ZClHh/oby3k10090	rigid:n4xAXAOqYXh1CN68jXiWJ3spgS8	false	mutation:34-34	-	-	-	psi-mi:"MI:0082"(peptide massfingerprinting)	psi-mi:"MI:0082"(peptide massfingerprinting)
uniprotkb:P97493-PRO_0000034151	uniprotkb:O08553	intact:EBI-26567598	intact:EBI-446064|uniprotkb:Q6P5D0|ensembl:ENSMUSP00000022629	psi-mi:p97493-pro_0000034151(display_long)|uniprotkb:Thioredoxin-2(gene name synonym)|uniprotkb:Txn2(gene name)|psi-mi:Txn2(display_short)	psi-mi:dpyl2_mouse(display_long)|uniprotkb:Unc-33-like phosphoprotein 2(gene name synonym)|uniprotkb:Dpysl2(gene name)|psi-mi:Dpysl2(display_short)|uniprotkb:Crmp2(gene name synonym)|uniprotkb:Ulip2(gene name synonym)	psi-mi:"MI:0096"(pull down)	Chasapis et al. (2019)	pubmed:31018154|imex:IM-28571	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26500426|imex:IM-28571-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	intact:EBI-8354432(chain-parent)	refseq:NP_034085.2|ensembl:ENSMUSG00000022048(gene)|ensembl:ENSMUST00000022629(transcript)|go:"GO:0001975"(response to amphetamine)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005886"(plasma membrane)|go:"GO:0006897"(endocytosis)|go:"GO:0007010"(cytoskeleton organization)|go:"GO:0007411"(axon guidance)|go:"GO:0008017"(microtubule binding)|go:"GO:0010975"(regulation of neuron projection development)|go:"GO:0014049"(positive regulation of glutamate secretion)|go:"GO:0016810"("hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds")|go:"GO:0019901"(protein kinase binding)|go:"GO:0021510"(spinal cord development)|go:"GO:0021772"(olfactory bulb development)|go:"GO:0030424"(axon)|go:"GO:0030425"(dendrite)|go:"GO:0030426"(growth cone)|go:"GO:0030516"(regulation of axon extension)|go:"GO:0032991"(protein-containing complex)|go:"GO:0042220"(response to cocaine)|go:"GO:0042493"|go:"GO:0042802"(identical protein binding)|go:"GO:0043005"(neuron projection)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043195"(terminal bouton)|go:"GO:0043209"(myelin sheath)|go:"GO:0045664"(regulation of neuron differentiation)|go:"GO:0048489"(synaptic vesicle transport)|go:"GO:0098793"(presynapse)|interpro:IPR006680(Amidohydrolase 1)|interpro:IPR011059(Metal-dependent hydrolase, composite)|interpro:IPR011778(D-hydantoinase)|interpro:IPR030615|interpro:IPR032466|mint:O08553|rcsb pdb:5UQC|reactome:R-MMU-399956|reactome:R-MMU-437239	-	chain-seq-start:60|chain-seq-end:166	-	figure legend:ST1.8|comment:DTT-eluted fraction|dataset:Rare diseases - Interactions investigated in the context of Rare genetic disease|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2020/12/04	2020/12/21	rogid:mvYK6+YgIN/WuGLBCWqsqPLfDyQ10090	rogid:97yc8TNEPMcGtGNRLvl+KV+DYr010090	rigid:n4xAXAOqYXh1CN68jXiWJ3spgS8	false	mutation:34-34	-	-	-	psi-mi:"MI:0082"(peptide massfingerprinting)	psi-mi:"MI:0082"(peptide massfingerprinting)
uniprotkb:P97493-PRO_0000034151	uniprotkb:Q9R0P5	intact:EBI-26567598	intact:EBI-1184008|ensembl:ENSMUSP00000099461	psi-mi:p97493-pro_0000034151(display_long)|uniprotkb:Thioredoxin-2(gene name synonym)|uniprotkb:Txn2(gene name)|psi-mi:Txn2(display_short)	psi-mi:dest_mouse(display_long)|uniprotkb:Dstn(gene name)|psi-mi:Dstn(display_short)|uniprotkb:Dsn(gene name synonym)|uniprotkb:Sid23(gene name synonym)|uniprotkb:Actin-depolymerizing factor(gene name synonym)|uniprotkb:Sid 23(gene name synonym)	psi-mi:"MI:0096"(pull down)	Chasapis et al. (2019)	pubmed:31018154|imex:IM-28571	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26500426|imex:IM-28571-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	intact:EBI-8354432(chain-parent)	refseq:NP_062745.1|ensembl:ENSMUSG00000015932(gene)|ensembl:ENSMUST00000103172(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0030042"(actin filament depolymerization)|go:"GO:0030043"(actin filament fragmentation)|go:"GO:0030836"(positive regulation of actin filament depolymerization)|go:"GO:0030864"(cortical actin cytoskeleton)|go:"GO:0048870"(cell motility)|go:"GO:0051014"(actin filament severing)|go:"GO:0051015"(actin filament binding)|interpro:IPR002108(Actin-binding, cofilin/tropomyosin type)|interpro:IPR017904|interpro:IPR029006|interpro:IPR029924|mint:Q9R0P5	-	chain-seq-start:60|chain-seq-end:166	-	figure legend:ST1.8|comment:DTT-eluted fraction|dataset:Rare diseases - Interactions investigated in the context of Rare genetic disease|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2020/12/04	2020/12/21	rogid:mvYK6+YgIN/WuGLBCWqsqPLfDyQ10090	rogid:hqPae8VWEKvGPITqHtrSs78yI4M10090	rigid:n4xAXAOqYXh1CN68jXiWJ3spgS8	false	mutation:34-34	-	-	-	psi-mi:"MI:0082"(peptide massfingerprinting)	psi-mi:"MI:0082"(peptide massfingerprinting)
uniprotkb:P97493-PRO_0000034151	uniprotkb:P56389	intact:EBI-26567598	intact:EBI-309606|uniprotkb:Q9D7V3|ensembl:ENSMUSP00000030535	psi-mi:p97493-pro_0000034151(display_long)|uniprotkb:Thioredoxin-2(gene name synonym)|uniprotkb:Txn2(gene name)|psi-mi:Txn2(display_short)	psi-mi:cdd_mouse(display_long)|uniprotkb:Cda(gene name)|psi-mi:Cda(display_short)|uniprotkb:Cdd(gene name synonym)|uniprotkb:Cytidine aminohydrolase(gene name synonym)	psi-mi:"MI:0096"(pull down)	Chasapis et al. (2019)	pubmed:31018154|imex:IM-28571	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26500426|imex:IM-28571-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	intact:EBI-8354432(chain-parent)	refseq:NP_082452.1|ensembl:ENSMUSG00000028755(gene)|ensembl:ENSMUST00000030535(transcript)|go:"GO:0001882"(nucleoside binding)|go:"GO:0004126"(cytidine deaminase activity)|go:"GO:0005829"(cytosol)|go:"GO:0006248"(CMP catabolic process)|go:"GO:0006249"(dCMP catabolic process)|go:"GO:0008270"(zinc ion binding)|go:"GO:0009972"(cytidine deamination)|go:"GO:0019239"(deaminase activity)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0045980"(negative regulation of nucleotide metabolic process)|go:"GO:0047844"(deoxycytidine deaminase activity)|interpro:IPR002125(CMP/dCMP deaminase, zinc-binding)|interpro:IPR006262(Cytidine deaminase, homotetrameric)|interpro:IPR016192(APOBEC/CMP deaminase, zinc-binding)|interpro:IPR016193(Cytidine deaminase-like)|mint:P56389|rcsb pdb:1ZAB|rcsb pdb:2FR5|rcsb pdb:2FR6|reactome:R-MMU-6798695|reactome:R-MMU-73614	-	chain-seq-start:60|chain-seq-end:166	-	figure legend:ST1.8|comment:DTT-eluted fraction|dataset:Rare diseases - Interactions investigated in the context of Rare genetic disease|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2020/12/04	2020/12/21	rogid:mvYK6+YgIN/WuGLBCWqsqPLfDyQ10090	rogid:dfGIMihZD9zI7FQJDq6Xc1E2Y6U10090	rigid:n4xAXAOqYXh1CN68jXiWJ3spgS8	false	mutation:34-34	-	-	-	psi-mi:"MI:0082"(peptide massfingerprinting)	psi-mi:"MI:0082"(peptide massfingerprinting)
uniprotkb:P97493-PRO_0000034151	uniprotkb:Q9WU84	intact:EBI-26567598	intact:EBI-11573066|uniprotkb:Q9CRJ9|ensembl:ENSMUSP00000035486	psi-mi:p97493-pro_0000034151(display_long)|uniprotkb:Thioredoxin-2(gene name synonym)|uniprotkb:Txn2(gene name)|psi-mi:Txn2(display_short)	psi-mi:ccs_mouse(display_long)|uniprotkb:Ccsd(gene name synonym)|uniprotkb:Superoxide dismutase copper chaperone(gene name synonym)|uniprotkb:Ccs(gene name)|psi-mi:Ccs(display_short)	psi-mi:"MI:0096"(pull down)	Chasapis et al. (2019)	pubmed:31018154|imex:IM-28571	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26500426|imex:IM-28571-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	intact:EBI-8354432(chain-parent)	refseq:NP_058588.1|ensembl:ENSMUSG00000034108(gene)|ensembl:ENSMUST00000037246(transcript)|go:"GO:0005507"(copper ion binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005758"(mitochondrial intermembrane space)|go:"GO:0019430"(removal of superoxide radicals)|go:"GO:0019899"(enzyme binding)|go:"GO:0051353"(positive regulation of oxidoreductase activity)|interpro:IPR001424(Superoxide dismutase, copper/zinc binding)|interpro:IPR006121(Heavy metal transport/detoxification protein)|interpro:IPR018152|interpro:IPR024134|interpro:IPR036163|interpro:IPR036423|mint:Q9WU84|reactome:R-MMU-3299685|dip:DIP-48692N	-	chain-seq-start:60|chain-seq-end:166	-	figure legend:ST1.8|comment:DTT-eluted fraction|dataset:Rare diseases - Interactions investigated in the context of Rare genetic disease|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2020/12/04	2020/12/21	rogid:mvYK6+YgIN/WuGLBCWqsqPLfDyQ10090	rogid:QOHBXTrPAST7wM1oj2wouOgbw8010090	rigid:n4xAXAOqYXh1CN68jXiWJ3spgS8	false	mutation:34-34	-	-	-	psi-mi:"MI:0082"(peptide massfingerprinting)	psi-mi:"MI:0082"(peptide massfingerprinting)
uniprotkb:P97493-PRO_0000034151	uniprotkb:P18760	intact:EBI-26567598	intact:EBI-1183994|ensembl:ENSMUSP00000147514	psi-mi:p97493-pro_0000034151(display_long)|uniprotkb:Thioredoxin-2(gene name synonym)|uniprotkb:Txn2(gene name)|psi-mi:Txn2(display_short)	psi-mi:cof1_mouse(display_long)|uniprotkb:Cfl1(gene name)|psi-mi:Cfl1(display_short)|uniprotkb:Cofilin, non-muscle isoform(gene name synonym)	psi-mi:"MI:0096"(pull down)	Chasapis et al. (2019)	pubmed:31018154|imex:IM-28571	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26500426|imex:IM-28571-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	intact:EBI-8354432(chain-parent)	refseq:NP_031713.1|ensembl:ENSMUSG00000056201(gene)|ensembl:ENSMUST00000209469(transcript)|go:"GO:0000281"(mitotic cytokinesis)|go:"GO:0001755"(neural crest cell migration)|go:"GO:0001842"(neural fold formation)|go:"GO:0003779"(actin binding)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005925"(focal adhesion)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0007010"(cytoskeleton organization)|go:"GO:0007015"(actin filament organization)|go:"GO:0007162"(negative regulation of cell adhesion)|go:"GO:0010592"(positive regulation of lamellipodium assembly)|go:"GO:0010593"(negative regulation of lamellipodium assembly)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0016363"(nuclear matrix)|go:"GO:0019903"(protein phosphatase binding)|go:"GO:0022604"(regulation of cell morphogenesis)|go:"GO:0030010"(establishment of cell polarity)|go:"GO:0030027"(lamellipodium)|go:"GO:0030030"(cell projection organization)|go:"GO:0030042"(actin filament depolymerization)|go:"GO:0030043"(actin filament fragmentation)|go:"GO:0030175"(filopodium)|go:"GO:0030307"(positive regulation of cell growth)|go:"GO:0030426"(growth cone)|go:"GO:0030835"(negative regulation of actin filament depolymerization)|go:"GO:0030836"(positive regulation of actin filament depolymerization)|go:"GO:0030864"(cortical actin cytoskeleton)|go:"GO:0031252"(cell leading edge)|go:"GO:0031258"(lamellipodium membrane)|go:"GO:0031915"(positive regulation of synaptic plasticity)|go:"GO:0031966"(mitochondrial membrane)|go:"GO:0032232"(negative regulation of actin filament bundle assembly)|go:"GO:0032587"(ruffle membrane)|go:"GO:0040019"(positive regulation of embryonic development)|go:"GO:0043005"(neuron projection)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043197"(dendritic spine)|go:"GO:0043200"(response to amino acid)|go:"GO:0044794"(positive regulation by host of viral process)|go:"GO:0045792"(negative regulation of cell size)|go:"GO:0045862"(positive regulation of proteolysis)|go:"GO:0048870"(cell motility)|go:"GO:0051014"(actin filament severing)|go:"GO:0051015"(actin filament binding)|go:"GO:0051293"(establishment of spindle localization)|go:"GO:0051511"(negative regulation of unidimensional cell growth)|go:"GO:0051894"(positive regulation of focal adhesion assembly)|go:"GO:0060999"(positive regulation of dendritic spine development)|go:"GO:0061001"(regulation of dendritic spine morphogenesis)|go:"GO:0070301"(cellular response to hydrogen peroxide)|go:"GO:0071347"(cellular response to interleukin-1)|go:"GO:0071354"(cellular response to interleukin-6)|go:"GO:0071356"(cellular response to tumor necrosis factor)|go:"GO:0071364"(cellular response to epidermal growth factor stimulus)|go:"GO:0090732"(cofilin-actin rod)|go:"GO:0097060"(synaptic membrane)|go:"GO:0098885"(modification of postsynaptic actin cytoskeleton)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:1902936"(phosphatidylinositol bisphosphate binding)|go:"GO:1902951"(negative regulation of dendritic spine maintenance)|go:"GO:1904783"(positive regulation of NMDA glutamate receptor activity)|go:"GO:1905873"(positive regulation of protein localization to cell leading edge)|go:"GO:1905875"(negative regulation of postsynaptic density organization)|go:"GO:1990314"(cellular response to insulin-like growth factor stimulus)|go:"GO:2000146"(negative regulation of cell motility)|go:"GO:2000147"(positive regulation of cell motility)|go:"GO:2000784"(positive regulation of establishment of cell polarity regulating cell shape)|go:"GO:2000814"(positive regulation of barbed-end actin filament capping)|interpro:IPR002108(Actin-binding, cofilin/tropomyosin type)|interpro:IPR017904|interpro:IPR027234|interpro:IPR029006|mint:P18760|dip:DIP-38073N	-	chain-seq-start:60|chain-seq-end:166	-	figure legend:ST1.8|comment:DTT-eluted fraction|dataset:Rare diseases - Interactions investigated in the context of Rare genetic disease|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2020/12/04	2020/12/21	rogid:mvYK6+YgIN/WuGLBCWqsqPLfDyQ10090	rogid:nw/9u2+2nq9Ef43SapV43MeOtjE10090	rigid:n4xAXAOqYXh1CN68jXiWJ3spgS8	false	mutation:34-34	-	-	-	psi-mi:"MI:0082"(peptide massfingerprinting)	psi-mi:"MI:0082"(peptide massfingerprinting)
uniprotkb:P97493-PRO_0000034151	uniprotkb:P53996	intact:EBI-26567598	intact:EBI-2552945|ensembl:ENSMUSP00000032138|uniprotkb:Q80Y06|uniprotkb:Q8BP23	psi-mi:p97493-pro_0000034151(display_long)|uniprotkb:Thioredoxin-2(gene name synonym)|uniprotkb:Txn2(gene name)|psi-mi:Txn2(display_short)	psi-mi:cnbp_mouse(display_long)|uniprotkb:Cnbp(gene name)|psi-mi:Cnbp(display_short)|uniprotkb:Cnbp1(gene name synonym)|uniprotkb:Znf9(gene name synonym)|uniprotkb:Zinc finger protein 9(gene name synonym)|uniprotkb:Cellular nucleic acid-binding protein(gene name synonym)	psi-mi:"MI:0096"(pull down)	Chasapis et al. (2019)	pubmed:31018154|imex:IM-28571	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26500426|imex:IM-28571-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	intact:EBI-8354432(chain-parent)	refseq:NP_001103215.1|refseq:NP_038521.1|ensembl:ENSMUSG00000030057(gene)|ensembl:ENSMUST00000032138(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0003727"(single-stranded RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005829"(cytosol)|go:"GO:0008270"(zinc ion binding)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0045182"(translation regulator activity)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0051880"(G-quadruplex DNA binding)|go:"GO:0071919"(G-quadruplex DNA formation)|go:"GO:2000767"(positive regulation of cytoplasmic translation)|interpro:IPR001878(Zinc finger, CCHC-type)|interpro:IPR036875|mint:P53996|refseq:NP_001334254.1	-	chain-seq-start:60|chain-seq-end:166	-	figure legend:ST1.8|comment:DTT-eluted fraction|dataset:Rare diseases - Interactions investigated in the context of Rare genetic disease|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2020/12/04	2020/12/21	rogid:mvYK6+YgIN/WuGLBCWqsqPLfDyQ10090	rogid:qXoAcOW8P42Ch0udEU00YlhTgn810090	rigid:n4xAXAOqYXh1CN68jXiWJ3spgS8	false	mutation:34-34	-	-	-	psi-mi:"MI:0082"(peptide massfingerprinting)	psi-mi:"MI:0082"(peptide massfingerprinting)
uniprotkb:P97493-PRO_0000034151	uniprotkb:P07356	intact:EBI-26567598	intact:EBI-738510|ensembl:ENSMUSP00000034756	psi-mi:p97493-pro_0000034151(display_long)|uniprotkb:Thioredoxin-2(gene name synonym)|uniprotkb:Txn2(gene name)|psi-mi:Txn2(display_short)	psi-mi:anxa2_mouse(display_long)|uniprotkb:Anxa2(gene name)|psi-mi:Anxa2(display_short)|uniprotkb:Anx2(gene name synonym)|uniprotkb:Cal1h(gene name synonym)|uniprotkb:Annexin-2(gene name synonym)|uniprotkb:Annexin II(gene name synonym)|uniprotkb:Lipocortin II(gene name synonym)|uniprotkb:Calpactin I heavy chain(gene name synonym)|uniprotkb:Chromobindin-8(gene name synonym)|uniprotkb:p36(gene name synonym)|uniprotkb:Protein I(gene name synonym)|uniprotkb:Placental anticoagulant protein IV(gene name synonym)|uniprotkb:Calpactin-1 heavy chain(gene name synonym)	psi-mi:"MI:0096"(pull down)	Chasapis et al. (2019)	pubmed:31018154|imex:IM-28571	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26500426|imex:IM-28571-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	intact:EBI-8354432(chain-parent)	refseq:NP_031611.1|refseq:XP_006510859.1|ensembl:ENSMUSG00000032231(gene)|ensembl:ENSMUST00000034756(transcript)|go:"GO:0001525"(angiogenesis)|go:"GO:0001726"(ruffle)|go:"GO:0001765"(membrane raft assembly)|go:"GO:0001786"(phosphatidylserine binding)|go:"GO:0001921"(positive regulation of receptor recycling)|go:"GO:0001934"(positive regulation of protein phosphorylation)|go:"GO:0002020"(protease binding)|go:"GO:0004867"(serine-type endopeptidase inhibitor activity)|go:"GO:0005262"(calcium channel activity)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005544"(calcium-dependent phospholipid binding)|go:"GO:0005546"(phosphatidylinositol-4,5-bisphosphate binding)|go:"GO:0005604"(basement membrane)|go:"GO:0005615"(extracellular space)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005768"(endosome)|go:"GO:0005769"(early endosome)|go:"GO:0005811"(lipid droplet)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005938"(cell cortex)|go:"GO:0006900"(vesicle budding from membrane)|go:"GO:0007589"(body fluid secretion)|go:"GO:0008092"(cytoskeletal protein binding)|go:"GO:0009986"(cell surface)|go:"GO:0016020"(membrane)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0019834"(phospholipase A2 inhibitor activity)|go:"GO:0019897"(extrinsic component of plasma membrane)|go:"GO:0030199"(collagen fibril organization)|go:"GO:0030496"(midbody)|go:"GO:0031267"(small GTPase binding)|go:"GO:0031340"(positive regulation of vesicle fusion)|go:"GO:0031902"(late endosome membrane)|go:"GO:0031982"(vesicle)|go:"GO:0032804"(negative regulation of low-density lipoprotein particle receptor catabolic process)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035749"(myelin sheath adaxonal region)|go:"GO:0036035"(osteoclast development)|go:"GO:0042383"(sarcolemma)|go:"GO:0042470"(melanosome)|go:"GO:0042730"(fibrinolysis)|go:"GO:0042802"(identical protein binding)|go:"GO:0043220"(Schmidt-Lanterman incisure)|go:"GO:0044090"(positive regulation of vacuole organization)|go:"GO:0044147"(negative regulation of formation of structure involved in a symbiotic process)|go:"GO:0044354"(macropinosome)|go:"GO:0044548"(S100 protein binding)|go:"GO:0044730"(bone sialoprotein binding)|go:"GO:0045121"(membrane raft)|go:"GO:0046790"(virion binding)|go:"GO:0048146"(positive regulation of fibroblast proliferation)|go:"GO:0048306"(calcium-dependent protein binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051099"(positive regulation of binding)|go:"GO:0052362"(obsolete catabolism by host of symbiont protein)|go:"GO:0052405"|go:"GO:0062023"(collagen-containing extracellular matrix)|go:"GO:0070062"(extracellular exosome)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0097066"(response to thyroid hormone)|go:"GO:1905581"(positive regulation of low-density lipoprotein particle clearance)|go:"GO:1905597"(positive regulation of low-density lipoprotein particle receptor binding)|go:"GO:1905599"(positive regulation of low-density lipoprotein receptor activity)|go:"GO:1905602"(positive regulation of receptor-mediated endocytosis involved in cholesterol transport)|go:"GO:1990665"(AnxA2-p11 complex)|go:"GO:1990667"(PCSK9-AnxA2 complex)|interpro:IPR001464(Annexin)|interpro:IPR002389(Annexin, type II)|interpro:IPR018252|interpro:IPR018502|interpro:IPR037104|mint:P07356|rcsb pdb:4HRE|reactome:R-MMU-6798695|reactome:R-MMU-75205	-	chain-seq-start:60|chain-seq-end:166	-	figure legend:ST1.8|comment:DTT-eluted fraction|dataset:Rare diseases - Interactions investigated in the context of Rare genetic disease|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2020/12/04	2020/12/21	rogid:mvYK6+YgIN/WuGLBCWqsqPLfDyQ10090	rogid:R7GyK+r4KmwX28VH2qQZF+Y729A10090	rigid:n4xAXAOqYXh1CN68jXiWJ3spgS8	false	mutation:34-34	-	-	-	psi-mi:"MI:0082"(peptide massfingerprinting)	psi-mi:"MI:0082"(peptide massfingerprinting)
uniprotkb:P97493-PRO_0000034151	uniprotkb:Q8R0Y6	intact:EBI-26567598	intact:EBI-773302|ensembl:ENSMUSP00000032175|ensembl:ENSMUSP00000114304	psi-mi:p97493-pro_0000034151(display_long)|uniprotkb:Thioredoxin-2(gene name synonym)|uniprotkb:Txn2(gene name)|psi-mi:Txn2(display_short)	psi-mi:al1l1_mouse(display_long)|uniprotkb:Aldh1l1(gene name)|psi-mi:Aldh1l1(display_short)|uniprotkb:Fthfd(gene name synonym)|uniprotkb:Aldehyde dehydrogenase family 1 member L1(gene name synonym)	psi-mi:"MI:0096"(pull down)	Chasapis et al. (2019)	pubmed:31018154|imex:IM-28571	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26500426|imex:IM-28571-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	intact:EBI-8354432(chain-parent)	refseq:NP_081682.1|refseq:XP_006505342.1|ensembl:ENSMUSG00000030088(gene)|ensembl:ENSMUST00000032175(transcript)|ensembl:ENSMUST00000130418(transcript)|go:"GO:0004029"("aldehyde dehydrogenase (NAD+) activity")|go:"GO:0004030"("aldehyde dehydrogenase [NAD(P)+] activity")|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0006730"(one-carbon metabolic process)|go:"GO:0009058"(biosynthetic process)|go:"GO:0009258"(10-formyltetrahydrofolate catabolic process)|go:"GO:0016155"(formyltetrahydrofolate dehydrogenase activity)|go:"GO:0016742"(hydroxymethyl-, formyl- and related transferase activity)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033721"("aldehyde dehydrogenase (NADP+) activity")|go:"GO:0044877"(protein-containing complex binding)|interpro:IPR001555(Phosphoribosylglycinamide formyltransferase, active site)|interpro:IPR002376(Formyl transferase, N-terminal)|interpro:IPR005793(Formyl transferase, C-terminal)|interpro:IPR009081(Acyl carrier protein-like)|interpro:IPR011034(Formyl transferase, C-terminal-like)|interpro:IPR011407(10-formyltetrahydrofolate dehydrogenase)|interpro:IPR015590(Aldehyde dehydrogenase)|interpro:IPR016160(Aldehyde dehydrogenase, conserved site)|interpro:IPR016161(Aldehyde/histidinol dehydrogenase)|interpro:IPR016162(Aldehyde dehydrogenase, N-terminal)|interpro:IPR016163(Aldehyde dehydrogenase, C-terminal)|interpro:IPR029510|interpro:IPR036477|interpro:IPR036736|interpro:IPR037022|mint:Q8R0Y6|reactome:R-MMU-196757	-	chain-seq-start:60|chain-seq-end:166	-	figure legend:ST1.8|comment:DTT-eluted fraction|dataset:Rare diseases - Interactions investigated in the context of Rare genetic disease|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2020/12/04	2020/12/21	rogid:mvYK6+YgIN/WuGLBCWqsqPLfDyQ10090	rogid:NPrpjLQwcvgssOGZORimttWUSMY10090	rigid:n4xAXAOqYXh1CN68jXiWJ3spgS8	false	mutation:34-34	-	-	-	psi-mi:"MI:0082"(peptide massfingerprinting)	psi-mi:"MI:0082"(peptide massfingerprinting)
uniprotkb:P97493-PRO_0000034151	uniprotkb:Q9DCT2	intact:EBI-26567598	intact:EBI-772758|uniprotkb:Q8BTZ3|uniprotkb:Q8R073|ensembl:ENSMUSP00000005647	psi-mi:p97493-pro_0000034151(display_long)|uniprotkb:Thioredoxin-2(gene name synonym)|uniprotkb:Txn2(gene name)|psi-mi:Txn2(display_short)	psi-mi:ndus3_mouse(display_long)|uniprotkb:NADH-ubiquinone oxidoreductase 30 kDa subunit(gene name synonym)|uniprotkb:Complex I-30kD(gene name synonym)|uniprotkb:Ndufs3(gene name)|psi-mi:Ndufs3(display_short)	psi-mi:"MI:0096"(pull down)	Chasapis et al. (2019)	pubmed:31018154|imex:IM-28571	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26500434|imex:IM-28571-25	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	intact:EBI-8354432(chain-parent)	refseq:NP_080964.1|dip:DIP-32378N|ensembl:ENSMUSG00000005510(gene)|ensembl:ENSMUST00000005647(transcript)|go:"GO:0003954"(NADH dehydrogenase activity)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005747"(mitochondrial respiratory chain complex I)|go:"GO:0006120"(mitochondrial electron transport, NADH to ubiquinone)|go:"GO:0008137"("NADH dehydrogenase (ubiquinone) activity")|go:"GO:0016604"(nuclear body)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0031966"(mitochondrial membrane)|go:"GO:0032981"(mitochondrial respiratory chain complex I assembly)|go:"GO:0043209"(myelin sheath)|go:"GO:0072593"(reactive oxygen species metabolic process)|go:"GO:2001243"(negative regulation of intrinsic apoptotic signaling pathway)|interpro:IPR001268("NADH dehydrogenase (ubiquinone), 30 kDa subunit")|interpro:IPR010218("NADH (or F420H2) dehydrogenase, subunit C")|interpro:IPR020396|interpro:IPR037232|mint:Q9DCT2|rcsb pdb:6G2J|rcsb pdb:6G72|rcsb pdb:6ZR2|rcsb pdb:6ZTQ|rcsb pdb:7AK5|rcsb pdb:7AK6|rcsb pdb:7B93|reactome:R-MMU-611105|reactome:R-MMU-6799198|reactome:R-MMU-9013408	go:"GO:0005739"(mitochondrion)	chain-seq-start:60|chain-seq-end:166	-	figure legend:ST1.9|comment:acid-eluted fraction|dataset:Rare diseases - Interactions investigated in the context of Rare genetic disease|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2020/12/04	2020/12/21	rogid:mvYK6+YgIN/WuGLBCWqsqPLfDyQ10090	rogid:2tQasToTy6/l6HeQwM+hTVH2Mow10090	rigid:zoEHsPY9YTLrRubU29K/0JFMxn0	false	mutation:34-34	-	-	-	psi-mi:"MI:0082"(peptide massfingerprinting)	psi-mi:"MI:0082"(peptide massfingerprinting)
uniprotkb:P97493-PRO_0000034151	uniprotkb:Q91WD5	intact:EBI-26567598	intact:EBI-772751|uniprotkb:Q3U5Y9|uniprotkb:Q3UJX7|uniprotkb:Q99L23|uniprotkb:Q3TNA8|ensembl:ENSMUSP00000013737	psi-mi:p97493-pro_0000034151(display_long)|uniprotkb:Thioredoxin-2(gene name synonym)|uniprotkb:Txn2(gene name)|psi-mi:Txn2(display_short)	psi-mi:ndus2_mouse(display_long)|uniprotkb:NADH-ubiquinone oxidoreductase 49 kDa subunit(gene name synonym)|uniprotkb:Complex I-49kD(gene name synonym)|uniprotkb:Ndufs2(gene name)|psi-mi:Ndufs2(display_short)	psi-mi:"MI:0096"(pull down)	Chasapis et al. (2019)	pubmed:31018154|imex:IM-28571	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26500434|imex:IM-28571-25	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	intact:EBI-8354432(chain-parent)	refseq:NP_694704.1|ensembl:ENSMUSG00000013593(gene)|ensembl:ENSMUST00000013737(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005747"(mitochondrial respiratory chain complex I)|go:"GO:0006120"(mitochondrial electron transport, NADH to ubiquinone)|go:"GO:0006979"(response to oxidative stress)|go:"GO:0008137"("NADH dehydrogenase (ubiquinone) activity")|go:"GO:0019826"(oxygen sensor activity)|go:"GO:0022008"(neurogenesis)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032981"(mitochondrial respiratory chain complex I assembly)|go:"GO:0042063"(gliogenesis)|go:"GO:0042775"(mitochondrial ATP synthesis coupled electron transport)|go:"GO:0046872"(metal ion binding)|go:"GO:0048038"(quinone binding)|go:"GO:0051287"(NAD binding)|go:"GO:0051539"(4 iron, 4 sulfur cluster binding)|go:"GO:0061351"(neural precursor cell proliferation)|go:"GO:0071453"(cellular response to oxygen levels)|interpro:IPR001135(NADH-ubiquinone oxidoreductase, chain 49kDa)|interpro:IPR014029(NADH-ubiquinone oxidoreductase, chain 49kDa, conserved site)|interpro:IPR022885|interpro:IPR029014|mint:Q91WD5|rcsb pdb:6G2J|rcsb pdb:6G72|rcsb pdb:6ZR2|rcsb pdb:6ZTQ|rcsb pdb:7AK5|rcsb pdb:7AK6|rcsb pdb:7B93|reactome:R-MMU-611105|reactome:R-MMU-6799198	go:"GO:0005739"(mitochondrion)	chain-seq-start:60|chain-seq-end:166	-	figure legend:ST1.9|comment:acid-eluted fraction|dataset:Rare diseases - Interactions investigated in the context of Rare genetic disease|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2020/12/04	2020/12/21	rogid:mvYK6+YgIN/WuGLBCWqsqPLfDyQ10090	rogid:dk8e26C1hIdTZvDnX5nE1n+juwk10090	rigid:zoEHsPY9YTLrRubU29K/0JFMxn0	false	mutation:34-34	-	-	-	psi-mi:"MI:0082"(peptide massfingerprinting)	psi-mi:"MI:0082"(peptide massfingerprinting)
uniprotkb:P97493-PRO_0000034151	uniprotkb:P16858	intact:EBI-26567598	intact:EBI-444871|uniprotkb:Q0QEU0|uniprotkb:Q3THM2|uniprotkb:Q3TUI2|uniprotkb:Q3UMT2|uniprotkb:Q4V783|uniprotkb:Q569X2|uniprotkb:Q569X5|uniprotkb:Q5U410|uniprotkb:A6H6A8|ensembl:ENSMUSP00000073289|ensembl:ENSMUSP00000113213	psi-mi:p97493-pro_0000034151(display_long)|uniprotkb:Thioredoxin-2(gene name synonym)|uniprotkb:Txn2(gene name)|psi-mi:Txn2(display_short)	psi-mi:g3p_mouse(display_long)|uniprotkb:Gapdh(gene name)|psi-mi:Gapdh(display_short)|uniprotkb:Gapd(gene name synonym)|uniprotkb:Peptidyl-cysteine S-nitrosylase GAPDH(gene name synonym)	psi-mi:"MI:0096"(pull down)	Chasapis et al. (2019)	pubmed:31018154|imex:IM-28571	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26500434|imex:IM-28571-25	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	intact:EBI-8354432(chain-parent)	refseq:NP_032110.1|refseq:XP_001476757.1|ensembl:ENSMUSG00000057666(gene)|ensembl:ENSMUST00000073605(transcript)|ensembl:ENSMUST00000118875(transcript)|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0001819"(positive regulation of cytokine production)|go:"GO:0004365"("glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity")|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005811"(lipid droplet)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005975"(carbohydrate metabolic process)|go:"GO:0006094"(gluconeogenesis)|go:"GO:0006096"(glycolytic process)|go:"GO:0006915"(apoptotic process)|go:"GO:0008017"(microtubule binding)|go:"GO:0010951"(negative regulation of endopeptidase activity)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0017148"(negative regulation of translation)|go:"GO:0019828"(aspartic-type endopeptidase inhibitor activity)|go:"GO:0019899"(enzyme binding)|go:"GO:0019933"(cAMP-mediated signaling)|go:"GO:0031640"(killing of cells of another organism)|go:"GO:0031906"(late endosome lumen)|go:"GO:0031965"(nuclear membrane)|go:"GO:0032481"(positive regulation of type I interferon production)|go:"GO:0035605"(peptidyl-cysteine S-nitrosylase activity)|go:"GO:0035606"(peptidyl-cysteine S-trans-nitrosylation)|go:"GO:0042802"(identical protein binding)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043209"(myelin sheath)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0050661"(NADP binding)|go:"GO:0050821"(protein stabilization)|go:"GO:0050832"(defense response to fungus)|go:"GO:0051287"(NAD binding)|go:"GO:0051402"(neuron apoptotic process)|go:"GO:0051873"(killing by host of symbiont cells)|go:"GO:0060359"(response to ammonium ion)|go:"GO:0061844"(antimicrobial humoral immune response mediated by antimicrobial peptide)|go:"GO:0071346"(cellular response to interferon-gamma)|go:"GO:0097452"(GAIT complex)|go:"GO:0097718"(disordered domain specific binding)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099092"(postsynaptic density, intracellular component)|go:"GO:1905460"(negative regulation of vascular associated smooth muscle cell apoptotic process)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR006424(Glyceraldehyde-3-phosphate dehydrogenase, type I)|interpro:IPR020828|interpro:IPR020829|interpro:IPR020830|interpro:IPR020831|interpro:IPR036291|mint:P16858|rcsb pdb:6LGJ|rcsb pdb:6LGK|rcsb pdb:6LGM|reactome:R-MMU-70171|reactome:R-MMU-70263|refseq:NP_001276655.1|dip:DIP-31404N	go:"GO:0005739"(mitochondrion)	chain-seq-start:60|chain-seq-end:166	-	figure legend:ST1.9|comment:acid-eluted fraction|dataset:Rare diseases - Interactions investigated in the context of Rare genetic disease|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2020/12/04	2020/12/21	rogid:mvYK6+YgIN/WuGLBCWqsqPLfDyQ10090	rogid:SkcdXZ+143DDQFioo6mNWNpCLTI10090	rigid:zoEHsPY9YTLrRubU29K/0JFMxn0	false	mutation:34-34	-	-	-	psi-mi:"MI:0082"(peptide massfingerprinting)	psi-mi:"MI:0082"(peptide massfingerprinting)
uniprotkb:P97493-PRO_0000034151	uniprotkb:Q9DCX2	intact:EBI-26567598	intact:EBI-2255503|uniprotkb:B1ASE1|uniprotkb:Q542H1|uniprotkb:Q7M0I0|uniprotkb:Q91YK9|ensembl:ENSMUSP00000046256|ensembl:ENSMUSP00000086072|ensembl:ENSMUSP00000102147|ensembl:ENSMUSP00000137071	psi-mi:p97493-pro_0000034151(display_long)|uniprotkb:Thioredoxin-2(gene name synonym)|uniprotkb:Txn2(gene name)|psi-mi:Txn2(display_short)	psi-mi:atp5h_mouse(display_long)|uniprotkb:Atp5pd(gene name)|psi-mi:Atp5pd(display_short)|uniprotkb:ATP synthase peripheral stalk subunit d(gene name synonym)|uniprotkb:Atp5h(gene name synonym)	psi-mi:"MI:0096"(pull down)	Chasapis et al. (2019)	pubmed:31018154|imex:IM-28571	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26500434|imex:IM-28571-25	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	intact:EBI-8354432(chain-parent)	refseq:NP_082138.1|refseq:XP_006534317.1|ensembl:ENSMUSG00000034566(gene)|ensembl:ENSMUST00000043931(transcript)|ensembl:ENSMUST00000073791(transcript)|ensembl:ENSMUST00000106537(transcript)|ensembl:ENSMUST00000180072(transcript)|go:"GO:0000274"(mitochondrial proton-transporting ATP synthase, stator stalk)|go:"GO:0000276"("mitochondrial proton-transporting ATP synthase complex, coupling factor F(o)")|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005753"(mitochondrial proton-transporting ATP synthase complex)|go:"GO:0015986"(ATP synthesis coupled proton transport)|go:"GO:0042776"(mitochondrial ATP synthesis coupled proton transport)|go:"GO:0043209"(myelin sheath)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0046034"(ATP metabolic process)|go:"GO:0046933"(proton-transporting ATP synthase activity, rotational mechanism)|go:"GO:1901653"(cellular response to peptide)|interpro:IPR008689(ATPase, F0 complex, subunit D, mitochondrial)|interpro:IPR036228|mint:Q9DCX2|reactome:R-MMU-163210|reactome:R-MMU-8949613	go:"GO:0005739"(mitochondrion)	chain-seq-start:60|chain-seq-end:166	-	figure legend:ST1.9|comment:acid-eluted fraction|dataset:Rare diseases - Interactions investigated in the context of Rare genetic disease|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2020/12/04	2020/12/21	rogid:mvYK6+YgIN/WuGLBCWqsqPLfDyQ10090	rogid:OJ9KqZtJ9IxSLv0aHm0DcOI9d7w10090	rigid:zoEHsPY9YTLrRubU29K/0JFMxn0	false	mutation:34-34	-	-	-	psi-mi:"MI:0082"(peptide massfingerprinting)	psi-mi:"MI:0082"(peptide massfingerprinting)
uniprotkb:P97493-PRO_0000034151	uniprotkb:P56480	intact:EBI-26567598	intact:EBI-299482|ensembl:ENSMUSP00000026459|uniprotkb:Q0QEP4|uniprotkb:Q3TFD7|uniprotkb:Q3TIP9|uniprotkb:Q3TK44|uniprotkb:Q3TWD5|uniprotkb:Q3TX28|uniprotkb:Q3U6U4|uniprotkb:Q3U774|uniprotkb:Q3UB69|uniprotkb:Q3UF69|uniprotkb:Q8CI65|uniprotkb:Q8VEJ5|uniprotkb:Q9CTI7|uniprotkb:Q9CWX7	psi-mi:p97493-pro_0000034151(display_long)|uniprotkb:Thioredoxin-2(gene name synonym)|uniprotkb:Txn2(gene name)|psi-mi:Txn2(display_short)	psi-mi:atpb_mouse(display_long)|uniprotkb:Atp5f1b(gene name)|psi-mi:Atp5f1b(display_short)|uniprotkb:ATP synthase F1 subunit beta(gene name synonym)|uniprotkb:Atp5b(gene name synonym)	psi-mi:"MI:0096"(pull down)	Chasapis et al. (2019)	pubmed:31018154|imex:IM-28571	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26500434|imex:IM-28571-25	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	intact:EBI-8354432(chain-parent)	interpro:IPR024034|interpro:IPR027417|interpro:IPR036121|mint:P56480|reactome:R-MMU-1268020|reactome:R-MMU-163210|reactome:R-MMU-8949613|interpro:IPR020003|ensembl:ENSMUSG00000025393(gene)|ensembl:ENSMUST00000026459(transcript)|go:"GO:0000275"("mitochondrial proton-transporting ATP synthase complex, catalytic sector F(1)")|go:"GO:0001525"(angiogenesis)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005753"(mitochondrial proton-transporting ATP synthase complex)|go:"GO:0005886"(plasma membrane)|go:"GO:0006629"(lipid metabolic process)|go:"GO:0006754"(ATP biosynthetic process)|go:"GO:0006898"(receptor-mediated endocytosis)|go:"GO:0006933"(negative regulation of cell adhesion involved in substrate-bound cell migration)|go:"GO:0009986"(cell surface)|go:"GO:0016020"(membrane)|go:"GO:0030228"(lipoprotein particle receptor activity)|go:"GO:0031966"(mitochondrial membrane)|go:"GO:0042288"(MHC class I protein binding)|go:"GO:0042645"(mitochondrial nucleoid)|go:"GO:0042776"(mitochondrial ATP synthesis coupled proton transport)|go:"GO:0043209"(myelin sheath)|go:"GO:0043531"(ADP binding)|go:"GO:0043532"(angiostatin binding)|go:"GO:0043536"(positive regulation of blood vessel endothelial cell migration)|go:"GO:0045121"(membrane raft)|go:"GO:0045259"(proton-transporting ATP synthase complex)|go:"GO:0045261"("proton-transporting ATP synthase complex, catalytic core F(1)")|go:"GO:0046034"(ATP metabolic process)|go:"GO:0046933"(proton-transporting ATP synthase activity, rotational mechanism)|go:"GO:0046961"(proton-transporting ATPase activity, rotational mechanism)|go:"GO:0051453"(regulation of intracellular pH)|go:"GO:0098761"(cellular response to interleukin-7)|go:"GO:1902600"(proton transmembrane transport)|interpro:IPR000194(ATPase, F1/V1/A1 complex, alpha/beta subunit, nucleotide-binding)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR004100(ATPase, F1/V1/A1 complex, alpha/beta subunit, N-terminal)|interpro:IPR005722(ATPase, F1 complex, beta subunit)|go:"GO:0005524"(ATP binding)|refseq:NP_058054.2	go:"GO:0005739"(mitochondrion)	chain-seq-start:60|chain-seq-end:166	-	figure legend:ST1.9|comment:acid-eluted fraction|dataset:Rare diseases - Interactions investigated in the context of Rare genetic disease|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2020/12/04	2020/12/21	rogid:mvYK6+YgIN/WuGLBCWqsqPLfDyQ10090	rogid:ihjn7GQ1ZSBfGcfwEAYSiCIuq+410090	rigid:zoEHsPY9YTLrRubU29K/0JFMxn0	false	mutation:34-34	-	-	-	psi-mi:"MI:0082"(peptide massfingerprinting)	psi-mi:"MI:0082"(peptide massfingerprinting)
uniprotkb:P97493-PRO_0000034151	uniprotkb:Q03265	intact:EBI-26567598	intact:EBI-299884|ensembl:ENSMUSP00000026495|uniprotkb:Q3TFN0|uniprotkb:Q3THN8|uniprotkb:Q3TPR0|uniprotkb:Q3TPV3|uniprotkb:Q3TZU3|uniprotkb:Q3UIR7|uniprotkb:Q543Y6	psi-mi:p97493-pro_0000034151(display_long)|uniprotkb:Thioredoxin-2(gene name synonym)|uniprotkb:Txn2(gene name)|psi-mi:Txn2(display_short)	psi-mi:atpa_mouse(display_long)|uniprotkb:Atp5f1a(gene name)|psi-mi:Atp5f1a(display_short)|uniprotkb:ATP synthase F1 subunit alpha(gene name synonym)|uniprotkb:Atp5a1(gene name synonym)	psi-mi:"MI:0096"(pull down)	Chasapis et al. (2019)	pubmed:31018154|imex:IM-28571	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26500434|imex:IM-28571-25	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	intact:EBI-8354432(chain-parent)	go:"GO:0005634"(nucleus)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005753"(mitochondrial proton-transporting ATP synthase complex)|ensembl:ENSMUSG00000025428(gene)|ensembl:ENSMUST00000026495(transcript)|go:"GO:0000275"("mitochondrial proton-transporting ATP synthase complex, catalytic sector F(1)")|go:"GO:0001937"(negative regulation of endothelial cell proliferation)|go:"GO:0002020"(protease binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005754"(mitochondrial proton-transporting ATP synthase, catalytic core)|go:"GO:0005886"(plasma membrane)|go:"GO:0006629"(lipid metabolic process)|go:"GO:0006754"(ATP biosynthetic process)|go:"GO:0008180"(COP9 signalosome)|go:"GO:0009986"(cell surface)|go:"GO:0015986"(ATP synthesis coupled proton transport)|go:"GO:0016020"(membrane)|go:"GO:0042288"(MHC class I protein binding)|go:"GO:0042776"(mitochondrial ATP synthesis coupled proton transport)|go:"GO:0043209"(myelin sheath)|go:"GO:0043531"(ADP binding)|go:"GO:0043532"(angiostatin binding)|go:"GO:0043536"(positive regulation of blood vessel endothelial cell migration)|go:"GO:0045121"(membrane raft)|go:"GO:0045259"(proton-transporting ATP synthase complex)|go:"GO:0045261"("proton-transporting ATP synthase complex, catalytic core F(1)")|go:"GO:0046034"(ATP metabolic process)|go:"GO:0046933"(proton-transporting ATP synthase activity, rotational mechanism)|interpro:IPR000194(ATPase, F1/V1/A1 complex, alpha/beta subunit, nucleotide-binding)|interpro:IPR000793(ATPase, F1/V1/A1 complex, alpha/beta subunit, C-terminal)|interpro:IPR004100(ATPase, F1/V1/A1 complex, alpha/beta subunit, N-terminal)|interpro:IPR005294(ATPase, F1 complex, alpha subunit)|interpro:IPR020003|interpro:IPR023366|interpro:IPR027417|interpro:IPR033732|interpro:IPR036121|interpro:IPR038376|mint:Q03265|reactome:R-MMU-163210|reactome:R-MMU-8949613|refseq:NP_031531.1	go:"GO:0005739"(mitochondrion)	chain-seq-start:60|chain-seq-end:166	-	figure legend:ST1.9|comment:acid-eluted fraction|dataset:Rare diseases - Interactions investigated in the context of Rare genetic disease|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2020/12/04	2020/12/21	rogid:mvYK6+YgIN/WuGLBCWqsqPLfDyQ10090	rogid:sBPTQwqC0dJTjZlZMKRzTSu6gHg10090	rigid:zoEHsPY9YTLrRubU29K/0JFMxn0	false	mutation:34-34	-	-	-	psi-mi:"MI:0082"(peptide massfingerprinting)	psi-mi:"MI:0082"(peptide massfingerprinting)
uniprotkb:P97493-PRO_0000034151	uniprotkb:Q9D051	intact:EBI-26567598	intact:EBI-773622|uniprotkb:Q3TL86|uniprotkb:Q505N8|uniprotkb:Q99LW9|ensembl:ENSMUSP00000022268	psi-mi:p97493-pro_0000034151(display_long)|uniprotkb:Thioredoxin-2(gene name synonym)|uniprotkb:Txn2(gene name)|psi-mi:Txn2(display_short)	psi-mi:odpb_mouse(display_long)|uniprotkb:Pdhb(gene name)|psi-mi:Pdhb(display_short)	psi-mi:"MI:0096"(pull down)	Chasapis et al. (2019)	pubmed:31018154|imex:IM-28571	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26500434|imex:IM-28571-25	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	intact:EBI-8354432(chain-parent)	refseq:NP_077183.1|ensembl:ENSMUSG00000021748(gene)|ensembl:ENSMUST00000022268(transcript)|go:"GO:0004739"("pyruvate dehydrogenase (acetyl-transferring) activity")|go:"GO:0005654"(nucleoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005967"(mitochondrial pyruvate dehydrogenase complex)|go:"GO:0006006"(glucose metabolic process)|go:"GO:0006086"(acetyl-CoA biosynthetic process from pyruvate)|go:"GO:0006099"(tricarboxylic acid cycle)|go:"GO:0034604"("pyruvate dehydrogenase (NAD+) activity")|go:"GO:0045254"(pyruvate dehydrogenase complex)|go:"GO:0061732"(mitochondrial acetyl-CoA biosynthetic process from pyruvate)|interpro:IPR005475(Transketolase, central region)|interpro:IPR009014(Transketolase, C-terminal/Pyruvate-ferredoxin oxidoreductase, domain II)|interpro:IPR027110|interpro:IPR029061|interpro:IPR033248|mint:Q9D051|reactome:R-MMU-204174|reactome:R-MMU-389661|reactome:R-MMU-5362517|reactome:R-MMU-70268	go:"GO:0005739"(mitochondrion)	chain-seq-start:60|chain-seq-end:166	-	figure legend:ST1.9|comment:acid-eluted fraction|dataset:Rare diseases - Interactions investigated in the context of Rare genetic disease|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2020/12/04	2020/12/21	rogid:mvYK6+YgIN/WuGLBCWqsqPLfDyQ10090	rogid:FPts4odLhVgLVf3gEYdc9N5Wuak10090	rigid:zoEHsPY9YTLrRubU29K/0JFMxn0	false	mutation:34-34	-	-	-	psi-mi:"MI:0082"(peptide massfingerprinting)	psi-mi:"MI:0082"(peptide massfingerprinting)
uniprotkb:P97493-PRO_0000034151	uniprotkb:P70404	intact:EBI-26567598	intact:EBI-773416|ensembl:ENSMUSP00000056502	psi-mi:p97493-pro_0000034151(display_long)|uniprotkb:Thioredoxin-2(gene name synonym)|uniprotkb:Txn2(gene name)|psi-mi:Txn2(display_short)	psi-mi:idhg1_mouse(display_long)|uniprotkb:Isocitric dehydrogenase subunit gamma(gene name synonym)|uniprotkb:"NAD(+)-specific ICDH subunit gamma"(gene name synonym)|uniprotkb:Idh3g(gene name)|psi-mi:Idh3g(display_short)	psi-mi:"MI:0096"(pull down)	Chasapis et al. (2019)	pubmed:31018154|imex:IM-28571	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26500434|imex:IM-28571-25	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	intact:EBI-8354432(chain-parent)	refseq:NP_032349.1|ensembl:ENSMUSG00000002010(gene)|ensembl:ENSMUST00000052761(transcript)|go:"GO:0000287"(magnesium ion binding)|go:"GO:0004449"("isocitrate dehydrogenase (NAD+) activity")|go:"GO:0005524"(ATP binding)|go:"GO:0005730"(nucleolus)|go:"GO:0005739"(mitochondrion)|go:"GO:0006099"(tricarboxylic acid cycle)|go:"GO:0006102"(isocitrate metabolic process)|go:"GO:0006103"(2-oxoglutarate metabolic process)|go:"GO:0006734"(NADH metabolic process)|go:"GO:0045926"(negative regulation of growth)|go:"GO:0051287"(NAD binding)|interpro:IPR004434(Isocitrate dehydrogenase NAD-dependent, mitochondrial)|interpro:IPR019818|interpro:IPR024084|mint:P70404|reactome:R-MMU-71403	go:"GO:0005739"(mitochondrion)	chain-seq-start:60|chain-seq-end:166	-	figure legend:ST1.9|comment:acid-eluted fraction|dataset:Rare diseases - Interactions investigated in the context of Rare genetic disease|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2020/12/04	2020/12/21	rogid:mvYK6+YgIN/WuGLBCWqsqPLfDyQ10090	rogid:0wCp92dH0hTrNyYmucC9Ob73aBU10090	rigid:zoEHsPY9YTLrRubU29K/0JFMxn0	false	mutation:34-34	-	-	-	psi-mi:"MI:0082"(peptide massfingerprinting)	psi-mi:"MI:0082"(peptide massfingerprinting)
uniprotkb:P97493-PRO_0000034151	uniprotkb:Q9CR68	intact:EBI-26567598	intact:EBI-1219616|uniprotkb:Q5SVV1|ensembl:ENSMUSP00000045284	psi-mi:p97493-pro_0000034151(display_long)|uniprotkb:Thioredoxin-2(gene name synonym)|uniprotkb:Txn2(gene name)|psi-mi:Txn2(display_short)	psi-mi:ucri_mouse(display_long)|uniprotkb:Rieske protein UQCRFS1(gene name synonym)|uniprotkb:Uqcrfs1(gene name)|psi-mi:Uqcrfs1(display_short)|uniprotkb:Rieske iron-sulfur protein(gene name synonym)|uniprotkb:Complex III subunit 5(gene name synonym)|uniprotkb:Ubiquinol-cytochrome c reductase iron-sulfur subunit(gene name synonym)|uniprotkb:Cytochrome b-c1 complex subunit 5(gene name synonym)	psi-mi:"MI:0096"(pull down)	Chasapis et al. (2019)	pubmed:31018154|imex:IM-28571	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26500434|imex:IM-28571-25	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	intact:EBI-8354432(chain-parent)	refseq:NP_079986.1|mint:Q9CR68|reactome:R-MMU-611105|ensembl:ENSMUSG00000038462(gene)|ensembl:ENSMUST00000042834(transcript)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005750"(mitochondrial respiratory chain complex III)|go:"GO:0005751"(mitochondrial respiratory chain complex IV)|go:"GO:0008121"(ubiquinol-cytochrome-c reductase activity)|go:"GO:0009725"(response to hormone)|go:"GO:0016491"(oxidoreductase activity)|go:"GO:0022904"(respiratory electron transport chain)|go:"GO:0031966"(mitochondrial membrane)|go:"GO:0034551"(mitochondrial respiratory chain complex III assembly)|go:"GO:0042493"|go:"GO:0043209"(myelin sheath)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0046677"(response to antibiotic)|go:"GO:0046872"(metal ion binding)|go:"GO:0051537"(2 iron, 2 sulfur cluster binding)|interpro:IPR004192(Ubiquinol cytochrome reductase transmembrane region)|interpro:IPR005805(Rieske iron-sulphur protein, C-terminal)|interpro:IPR006317(Ubiquinol-cytochrome c reductase, iron-sulphur subunit)|interpro:IPR011070(Globular protein, non-globular alpha/beta subunit)|interpro:IPR014349(Rieske iron-sulphur protein)|interpro:IPR015248(Ubiquinol-cytochrome c reductase 8 kDa, N-terminal)|interpro:IPR017941|interpro:IPR036922|interpro:IPR037008	go:"GO:0005739"(mitochondrion)	chain-seq-start:60|chain-seq-end:166	-	figure legend:ST1.9|comment:acid-eluted fraction|dataset:Rare diseases - Interactions investigated in the context of Rare genetic disease|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2020/12/04	2020/12/21	rogid:mvYK6+YgIN/WuGLBCWqsqPLfDyQ10090	rogid:nlXLFf9AMJ4fhZUsdE8cVraBuW410090	rigid:zoEHsPY9YTLrRubU29K/0JFMxn0	false	mutation:34-34	-	-	-	psi-mi:"MI:0082"(peptide massfingerprinting)	psi-mi:"MI:0082"(peptide massfingerprinting)
uniprotkb:P97493-PRO_0000034151	uniprotkb:O08807	intact:EBI-26567598	intact:EBI-494652|uniprotkb:Q3U8E4|uniprotkb:B1AZS7|ensembl:ENSMUSP00000026328	psi-mi:p97493-pro_0000034151(display_long)|uniprotkb:Thioredoxin-2(gene name synonym)|uniprotkb:Txn2(gene name)|psi-mi:Txn2(display_short)	psi-mi:prdx4_mouse(display_long)|uniprotkb:Peroxiredoxin IV(gene name synonym)|uniprotkb:Thioredoxin peroxidase AO372(gene name synonym)|uniprotkb:Thioredoxin-dependent peroxide reductase A0372(gene name synonym)|uniprotkb:Antioxidant enzyme AOE372(gene name synonym)|uniprotkb:Thioredoxin-dependent peroxiredoxin 4(gene name synonym)|uniprotkb:Prdx4(gene name)|psi-mi:Prdx4(display_short)	psi-mi:"MI:0096"(pull down)	Chasapis et al. (2019)	pubmed:31018154|imex:IM-28571	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26500442|imex:IM-28571-5	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	intact:EBI-8354432(chain-parent)	refseq:NP_058044.1|refseq:NP_001300640.1|dip:DIP-34137N|ensembl:ENSMUSG00000025289(gene)|ensembl:ENSMUST00000026328(transcript)|go:"GO:0004601"(peroxidase activity)|go:"GO:0005615"(extracellular space)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005790"(smooth endoplasmic reticulum)|go:"GO:0005829"(cytosol)|go:"GO:0006979"(response to oxidative stress)|go:"GO:0007283"(spermatogenesis)|go:"GO:0008584"(male gonad development)|go:"GO:0018401"(peptidyl-proline hydroxylation to 4-hydroxy-L-proline)|go:"GO:0022417"(protein maturation by protein folding)|go:"GO:0030198"(extracellular matrix organization)|go:"GO:0042802"(identical protein binding)|go:"GO:0045454"(cell redox homeostasis)|go:"GO:0051920"(peroxiredoxin activity)|go:"GO:0072593"(reactive oxygen species metabolic process)|go:"GO:2000255"(negative regulation of male germ cell proliferation)|interpro:IPR000866(Alkyl hydroperoxide reductase/ Thiol specific antioxidant/ Mal allergen)|interpro:IPR013766(Thioredoxin domain)|interpro:IPR019479|interpro:IPR036249|mint:O08807|rcsb pdb:3VWU|rcsb pdb:3VWV|rcsb pdb:3W8J|rcsb pdb:3WGX|reactome:R-MMU-6798695	go:"GO:0005739"(mitochondrion)	chain-seq-start:60|chain-seq-end:166	-	figure legend:ST1.10|comment:DTT-eluted fraction|dataset:Rare diseases - Interactions investigated in the context of Rare genetic disease|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2020/12/04	2020/12/21	rogid:mvYK6+YgIN/WuGLBCWqsqPLfDyQ10090	rogid:86EzEedrO6v5Z2dnSB2fSPaV2hc10090	rigid:RFCmtElBNW02qwaB3RaUI2EVXvM	false	mutation:34-34	-	-	-	psi-mi:"MI:0082"(peptide massfingerprinting)	psi-mi:"MI:0082"(peptide massfingerprinting)
uniprotkb:P97493-PRO_0000034151	uniprotkb:Q61171	intact:EBI-26567598	intact:EBI-444957|uniprotkb:O88376|uniprotkb:Q60796|uniprotkb:Q9CWJ4|uniprotkb:Q9DB49|ensembl:ENSMUSP00000005292|ensembl:ENSMUSP00000105355|ensembl:ENSMUSP00000105356|ensembl:ENSMUSP00000126451	psi-mi:p97493-pro_0000034151(display_long)|uniprotkb:Thioredoxin-2(gene name synonym)|uniprotkb:Txn2(gene name)|psi-mi:Txn2(display_short)	psi-mi:prdx2_mouse(display_long)|uniprotkb:Thioredoxin-dependent peroxiredoxin 2(gene name synonym)|uniprotkb:Thioredoxin peroxidase 1(gene name synonym)|uniprotkb:Thioredoxin-dependent peroxide reductase 1(gene name synonym)|uniprotkb:Thiol-specific antioxidant protein(gene name synonym)|uniprotkb:Prdx2(gene name)|psi-mi:Prdx2(display_short)|uniprotkb:Tdpx1(gene name synonym)|uniprotkb:Tpx(gene name synonym)	psi-mi:"MI:0096"(pull down)	Chasapis et al. (2019)	pubmed:31018154|imex:IM-28571	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26500442|imex:IM-28571-5	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	intact:EBI-8354432(chain-parent)	refseq:NP_035693.3|go:"GO:0042098"(T cell proliferation)|go:"GO:0042743"(hydrogen peroxide metabolic process)|go:"GO:0042744"(hydrogen peroxide catabolic process)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0043209"(myelin sheath)|go:"GO:0043410"(positive regulation of MAPK cascade)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0045321"(leukocyte activation)|go:"GO:0045454"(cell redox homeostasis)|go:"GO:0045581"(negative regulation of T cell differentiation)|go:"GO:0048538"(thymus development)|go:"GO:0048872"(homeostasis of number of cells)|go:"GO:2001237"(negative regulation of extrinsic apoptotic signaling pathway)|go:"GO:2001240"(negative regulation of extrinsic apoptotic signaling pathway in absence of ligand)|interpro:IPR000866(Alkyl hydroperoxide reductase/ Thiol specific antioxidant/ Mal allergen)|interpro:IPR013766(Thioredoxin domain)|interpro:IPR019479|interpro:IPR024706|interpro:IPR036249|mint:Q61171|reactome:R-MMU-3299685|reactome:R-MMU-5628897|go:"GO:0034599"(cellular response to oxidative stress)|refseq:NP_001304314.1|ensembl:ENSMUSG00000005161(gene)|ensembl:ENSMUST00000005292(transcript)|ensembl:ENSMUST00000109733(transcript)|ensembl:ENSMUST00000109734(transcript)|ensembl:ENSMUST00000164807(transcript)|go:"GO:0002357"(defense response to tumor cell)|go:"GO:0002536"(respiratory burst involved in inflammatory response)|go:"GO:0004601"(peroxidase activity)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0006979"(response to oxidative stress)|go:"GO:0008379"(thioredoxin peroxidase activity)|go:"GO:0008430"(selenium binding)|go:"GO:0010310"(regulation of hydrogen peroxide metabolic process)|go:"GO:0016209"(antioxidant activity)|go:"GO:0019430"(removal of superoxide radicals)|go:"GO:0030194"(positive regulation of blood coagulation)|go:"GO:0031665"(negative regulation of lipopolysaccharide-mediated signaling pathway)|go:"GO:0032088"(negative regulation of NF-kappaB transcription factor activity)|go:"GO:0032496"(response to lipopolysaccharide)	go:"GO:0005739"(mitochondrion)	chain-seq-start:60|chain-seq-end:166	-	figure legend:ST1.10|comment:DTT-eluted fraction|dataset:Rare diseases - Interactions investigated in the context of Rare genetic disease|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2020/12/04	2020/12/21	rogid:mvYK6+YgIN/WuGLBCWqsqPLfDyQ10090	rogid:P1NxwIOnv1n4sNzQWtFjy2znSbA10090	rigid:RFCmtElBNW02qwaB3RaUI2EVXvM	false	mutation:34-34	-	-	-	psi-mi:"MI:0082"(peptide massfingerprinting)	psi-mi:"MI:0082"(peptide massfingerprinting)
uniprotkb:P97493-PRO_0000034151	uniprotkb:P35700	intact:EBI-26567598	intact:EBI-444948|uniprotkb:Q3UBV4|uniprotkb:Q9CWI2|ensembl:ENSMUSP00000102078|ensembl:ENSMUSP00000114159	psi-mi:p97493-pro_0000034151(display_long)|uniprotkb:Thioredoxin-2(gene name synonym)|uniprotkb:Txn2(gene name)|psi-mi:Txn2(display_short)	psi-mi:prdx1_mouse(display_long)|uniprotkb:Thioredoxin-dependent peroxiredoxin 1(gene name synonym)|uniprotkb:Thioredoxin-dependent peroxide reductase 2(gene name synonym)|uniprotkb:Osteoblast-specific factor 3(gene name synonym)|uniprotkb:Macrophage 23 kDa stress protein(gene name synonym)|uniprotkb:Thioredoxin peroxidase 2(gene name synonym)|uniprotkb:Prdx1(gene name)|psi-mi:Prdx1(display_short)|uniprotkb:Msp23(gene name synonym)|uniprotkb:Paga(gene name synonym)|uniprotkb:Tdpx2(gene name synonym)	psi-mi:"MI:0096"(pull down)	Chasapis et al. (2019)	pubmed:31018154|imex:IM-28571	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26500442|imex:IM-28571-5	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	intact:EBI-8354432(chain-parent)	refseq:NP_035164.1|ensembl:ENSMUST00000135573(transcript)|go:"GO:0000302"(response to reactive oxygen species)|go:"GO:0000791"(euchromatin)|go:"GO:0004601"(peroxidase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0005782"(peroxisomal matrix)|go:"GO:0005829"(cytosol)|go:"GO:0006979"(response to oxidative stress)|go:"GO:0008283"(cell population proliferation)|go:"GO:0008379"(thioredoxin peroxidase activity)|go:"GO:0019430"(removal of superoxide radicals)|go:"GO:0020037"(heme binding)|go:"GO:0030101"(natural killer cell activation)|go:"GO:0032872"(regulation of stress-activated MAPK cascade)|go:"GO:0034101"(erythrocyte homeostasis)|go:"GO:0042267"(natural killer cell mediated cytotoxicity)|go:"GO:0042744"(hydrogen peroxide catabolic process)|go:"GO:0042802"(identical protein binding)|go:"GO:0043209"(myelin sheath)|go:"GO:0045321"(leukocyte activation)|go:"GO:0045454"(cell redox homeostasis)|go:"GO:0051920"(peroxiredoxin activity)|go:"GO:1901222"(regulation of NIK/NF-kappaB signaling)|interpro:IPR000866(Alkyl hydroperoxide reductase/ Thiol specific antioxidant/ Mal allergen)|interpro:IPR013766(Thioredoxin domain)|interpro:IPR019479|interpro:IPR024706|interpro:IPR036249|mint:P35700|reactome:R-MMU-3299685|reactome:R-MMU-5628897|ensembl:ENSMUST00000106470(transcript)|ensembl:ENSMUSG00000028691(gene)	go:"GO:0005739"(mitochondrion)	chain-seq-start:60|chain-seq-end:166	-	figure legend:ST1.10|comment:DTT-eluted fraction|dataset:Rare diseases - Interactions investigated in the context of Rare genetic disease|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2020/12/04	2020/12/21	rogid:mvYK6+YgIN/WuGLBCWqsqPLfDyQ10090	rogid:xOppWev1GtpILoJ1rY+tSPoymVU10090	rigid:RFCmtElBNW02qwaB3RaUI2EVXvM	false	mutation:34-34	-	-	-	psi-mi:"MI:0082"(peptide massfingerprinting)	psi-mi:"MI:0082"(peptide massfingerprinting)
uniprotkb:P97493-PRO_0000034151	uniprotkb:Q9D6R2	intact:EBI-26567598	intact:EBI-299873|ensembl:ENSMUSP00000127526|uniprotkb:Q3UAM8|uniprotkb:Q8C8A1|uniprotkb:Q9D1L1	psi-mi:p97493-pro_0000034151(display_long)|uniprotkb:Thioredoxin-2(gene name synonym)|uniprotkb:Txn2(gene name)|psi-mi:Txn2(display_short)	psi-mi:idh3a_mouse(display_long)|uniprotkb:Idh3a(gene name)|psi-mi:Idh3a(display_short)|uniprotkb:Isocitric dehydrogenase subunit alpha(gene name synonym)|uniprotkb:"NAD(+)-specific ICDH subunit alpha"(gene name synonym)	psi-mi:"MI:0096"(pull down)	Chasapis et al. (2019)	pubmed:31018154|imex:IM-28571	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26500442|imex:IM-28571-5	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	intact:EBI-8354432(chain-parent)	ensembl:ENSMUSG00000032279(gene)|ensembl:ENSMUST00000167866(transcript)|go:"GO:0000287"(magnesium ion binding)|go:"GO:0004449"("isocitrate dehydrogenase (NAD+) activity")|go:"GO:0005739"(mitochondrion)|go:"GO:0006099"(tricarboxylic acid cycle)|go:"GO:0006102"(isocitrate metabolic process)|go:"GO:0006103"(2-oxoglutarate metabolic process)|go:"GO:0006734"(NADH metabolic process)|go:"GO:0043209"(myelin sheath)|go:"GO:0051287"(NAD binding)|interpro:IPR004434(Isocitrate dehydrogenase NAD-dependent, mitochondrial)|interpro:IPR019818|interpro:IPR024084|mint:Q9D6R2|reactome:R-MMU-71403|refseq:NP_083849.1	go:"GO:0005739"(mitochondrion)	chain-seq-start:60|chain-seq-end:166	-	figure legend:ST1.10|comment:DTT-eluted fraction|dataset:Rare diseases - Interactions investigated in the context of Rare genetic disease|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2020/12/04	2020/12/21	rogid:mvYK6+YgIN/WuGLBCWqsqPLfDyQ10090	rogid:JkEkbIT34WQdoOiBYA9kAao2lC010090	rigid:RFCmtElBNW02qwaB3RaUI2EVXvM	false	mutation:34-34	-	-	-	psi-mi:"MI:0082"(peptide massfingerprinting)	psi-mi:"MI:0082"(peptide massfingerprinting)
uniprotkb:P97493-PRO_0000034151	uniprotkb:P16858	intact:EBI-26567598	intact:EBI-444871|uniprotkb:Q0QEU0|uniprotkb:Q3THM2|uniprotkb:Q3TUI2|uniprotkb:Q3UMT2|uniprotkb:Q4V783|uniprotkb:Q569X2|uniprotkb:Q569X5|uniprotkb:Q5U410|uniprotkb:A6H6A8|ensembl:ENSMUSP00000073289|ensembl:ENSMUSP00000113213	psi-mi:p97493-pro_0000034151(display_long)|uniprotkb:Thioredoxin-2(gene name synonym)|uniprotkb:Txn2(gene name)|psi-mi:Txn2(display_short)	psi-mi:g3p_mouse(display_long)|uniprotkb:Gapdh(gene name)|psi-mi:Gapdh(display_short)|uniprotkb:Gapd(gene name synonym)|uniprotkb:Peptidyl-cysteine S-nitrosylase GAPDH(gene name synonym)	psi-mi:"MI:0096"(pull down)	Chasapis et al. (2019)	pubmed:31018154|imex:IM-28571	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26500442|imex:IM-28571-5	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	intact:EBI-8354432(chain-parent)	refseq:NP_032110.1|refseq:XP_001476757.1|ensembl:ENSMUSG00000057666(gene)|ensembl:ENSMUST00000073605(transcript)|ensembl:ENSMUST00000118875(transcript)|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0001819"(positive regulation of cytokine production)|go:"GO:0004365"("glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity")|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005811"(lipid droplet)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005975"(carbohydrate metabolic process)|go:"GO:0006094"(gluconeogenesis)|go:"GO:0006096"(glycolytic process)|go:"GO:0006915"(apoptotic process)|go:"GO:0008017"(microtubule binding)|go:"GO:0010951"(negative regulation of endopeptidase activity)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0017148"(negative regulation of translation)|go:"GO:0019828"(aspartic-type endopeptidase inhibitor activity)|go:"GO:0019899"(enzyme binding)|go:"GO:0019933"(cAMP-mediated signaling)|go:"GO:0031640"(killing of cells of another organism)|go:"GO:0031906"(late endosome lumen)|go:"GO:0031965"(nuclear membrane)|go:"GO:0032481"(positive regulation of type I interferon production)|go:"GO:0035605"(peptidyl-cysteine S-nitrosylase activity)|go:"GO:0035606"(peptidyl-cysteine S-trans-nitrosylation)|go:"GO:0042802"(identical protein binding)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043209"(myelin sheath)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0050661"(NADP binding)|go:"GO:0050821"(protein stabilization)|go:"GO:0050832"(defense response to fungus)|go:"GO:0051287"(NAD binding)|go:"GO:0051402"(neuron apoptotic process)|go:"GO:0051873"(killing by host of symbiont cells)|go:"GO:0060359"(response to ammonium ion)|go:"GO:0061844"(antimicrobial humoral immune response mediated by antimicrobial peptide)|go:"GO:0071346"(cellular response to interferon-gamma)|go:"GO:0097452"(GAIT complex)|go:"GO:0097718"(disordered domain specific binding)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099092"(postsynaptic density, intracellular component)|go:"GO:1905460"(negative regulation of vascular associated smooth muscle cell apoptotic process)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR006424(Glyceraldehyde-3-phosphate dehydrogenase, type I)|interpro:IPR020828|interpro:IPR020829|interpro:IPR020830|interpro:IPR020831|interpro:IPR036291|mint:P16858|rcsb pdb:6LGJ|rcsb pdb:6LGK|rcsb pdb:6LGM|reactome:R-MMU-70171|reactome:R-MMU-70263|refseq:NP_001276655.1|dip:DIP-31404N	go:"GO:0005739"(mitochondrion)	chain-seq-start:60|chain-seq-end:166	-	figure legend:ST1.10|comment:DTT-eluted fraction|dataset:Rare diseases - Interactions investigated in the context of Rare genetic disease|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2020/12/04	2020/12/21	rogid:mvYK6+YgIN/WuGLBCWqsqPLfDyQ10090	rogid:SkcdXZ+143DDQFioo6mNWNpCLTI10090	rigid:RFCmtElBNW02qwaB3RaUI2EVXvM	false	mutation:34-34	-	-	-	psi-mi:"MI:0082"(peptide massfingerprinting)	psi-mi:"MI:0082"(peptide massfingerprinting)
uniprotkb:P97493-PRO_0000034151	uniprotkb:Q9CR68	intact:EBI-26567598	intact:EBI-1219616|uniprotkb:Q5SVV1|ensembl:ENSMUSP00000045284	psi-mi:p97493-pro_0000034151(display_long)|uniprotkb:Thioredoxin-2(gene name synonym)|uniprotkb:Txn2(gene name)|psi-mi:Txn2(display_short)	psi-mi:ucri_mouse(display_long)|uniprotkb:Rieske protein UQCRFS1(gene name synonym)|uniprotkb:Uqcrfs1(gene name)|psi-mi:Uqcrfs1(display_short)|uniprotkb:Rieske iron-sulfur protein(gene name synonym)|uniprotkb:Complex III subunit 5(gene name synonym)|uniprotkb:Ubiquinol-cytochrome c reductase iron-sulfur subunit(gene name synonym)|uniprotkb:Cytochrome b-c1 complex subunit 5(gene name synonym)	psi-mi:"MI:0096"(pull down)	Chasapis et al. (2019)	pubmed:31018154|imex:IM-28571	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26500442|imex:IM-28571-5	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	intact:EBI-8354432(chain-parent)	refseq:NP_079986.1|mint:Q9CR68|reactome:R-MMU-611105|ensembl:ENSMUSG00000038462(gene)|ensembl:ENSMUST00000042834(transcript)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005750"(mitochondrial respiratory chain complex III)|go:"GO:0005751"(mitochondrial respiratory chain complex IV)|go:"GO:0008121"(ubiquinol-cytochrome-c reductase activity)|go:"GO:0009725"(response to hormone)|go:"GO:0016491"(oxidoreductase activity)|go:"GO:0022904"(respiratory electron transport chain)|go:"GO:0031966"(mitochondrial membrane)|go:"GO:0034551"(mitochondrial respiratory chain complex III assembly)|go:"GO:0042493"|go:"GO:0043209"(myelin sheath)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0046677"(response to antibiotic)|go:"GO:0046872"(metal ion binding)|go:"GO:0051537"(2 iron, 2 sulfur cluster binding)|interpro:IPR004192(Ubiquinol cytochrome reductase transmembrane region)|interpro:IPR005805(Rieske iron-sulphur protein, C-terminal)|interpro:IPR006317(Ubiquinol-cytochrome c reductase, iron-sulphur subunit)|interpro:IPR011070(Globular protein, non-globular alpha/beta subunit)|interpro:IPR014349(Rieske iron-sulphur protein)|interpro:IPR015248(Ubiquinol-cytochrome c reductase 8 kDa, N-terminal)|interpro:IPR017941|interpro:IPR036922|interpro:IPR037008	go:"GO:0005739"(mitochondrion)	chain-seq-start:60|chain-seq-end:166	-	figure legend:ST1.10|comment:DTT-eluted fraction|dataset:Rare diseases - Interactions investigated in the context of Rare genetic disease|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2020/12/04	2020/12/21	rogid:mvYK6+YgIN/WuGLBCWqsqPLfDyQ10090	rogid:nlXLFf9AMJ4fhZUsdE8cVraBuW410090	rigid:RFCmtElBNW02qwaB3RaUI2EVXvM	false	mutation:34-34	-	-	-	psi-mi:"MI:0082"(peptide massfingerprinting)	psi-mi:"MI:0082"(peptide massfingerprinting)
uniprotkb:P97493-PRO_0000034151	uniprotkb:Q9DCX2	intact:EBI-26567598	intact:EBI-2255503|uniprotkb:B1ASE1|uniprotkb:Q542H1|uniprotkb:Q7M0I0|uniprotkb:Q91YK9|ensembl:ENSMUSP00000046256|ensembl:ENSMUSP00000086072|ensembl:ENSMUSP00000102147|ensembl:ENSMUSP00000137071	psi-mi:p97493-pro_0000034151(display_long)|uniprotkb:Thioredoxin-2(gene name synonym)|uniprotkb:Txn2(gene name)|psi-mi:Txn2(display_short)	psi-mi:atp5h_mouse(display_long)|uniprotkb:Atp5pd(gene name)|psi-mi:Atp5pd(display_short)|uniprotkb:ATP synthase peripheral stalk subunit d(gene name synonym)|uniprotkb:Atp5h(gene name synonym)	psi-mi:"MI:0096"(pull down)	Chasapis et al. (2019)	pubmed:31018154|imex:IM-28571	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26500442|imex:IM-28571-5	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	intact:EBI-8354432(chain-parent)	refseq:NP_082138.1|refseq:XP_006534317.1|ensembl:ENSMUSG00000034566(gene)|ensembl:ENSMUST00000043931(transcript)|ensembl:ENSMUST00000073791(transcript)|ensembl:ENSMUST00000106537(transcript)|ensembl:ENSMUST00000180072(transcript)|go:"GO:0000274"(mitochondrial proton-transporting ATP synthase, stator stalk)|go:"GO:0000276"("mitochondrial proton-transporting ATP synthase complex, coupling factor F(o)")|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005753"(mitochondrial proton-transporting ATP synthase complex)|go:"GO:0015986"(ATP synthesis coupled proton transport)|go:"GO:0042776"(mitochondrial ATP synthesis coupled proton transport)|go:"GO:0043209"(myelin sheath)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0046034"(ATP metabolic process)|go:"GO:0046933"(proton-transporting ATP synthase activity, rotational mechanism)|go:"GO:1901653"(cellular response to peptide)|interpro:IPR008689(ATPase, F0 complex, subunit D, mitochondrial)|interpro:IPR036228|mint:Q9DCX2|reactome:R-MMU-163210|reactome:R-MMU-8949613	go:"GO:0005739"(mitochondrion)	chain-seq-start:60|chain-seq-end:166	-	figure legend:ST1.10|comment:DTT-eluted fraction|dataset:Rare diseases - Interactions investigated in the context of Rare genetic disease|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2020/12/04	2020/12/21	rogid:mvYK6+YgIN/WuGLBCWqsqPLfDyQ10090	rogid:OJ9KqZtJ9IxSLv0aHm0DcOI9d7w10090	rigid:RFCmtElBNW02qwaB3RaUI2EVXvM	false	mutation:34-34	-	-	-	psi-mi:"MI:0082"(peptide massfingerprinting)	psi-mi:"MI:0082"(peptide massfingerprinting)
uniprotkb:P97493-PRO_0000034151	uniprotkb:P56480	intact:EBI-26567598	intact:EBI-299482|ensembl:ENSMUSP00000026459|uniprotkb:Q0QEP4|uniprotkb:Q3TFD7|uniprotkb:Q3TIP9|uniprotkb:Q3TK44|uniprotkb:Q3TWD5|uniprotkb:Q3TX28|uniprotkb:Q3U6U4|uniprotkb:Q3U774|uniprotkb:Q3UB69|uniprotkb:Q3UF69|uniprotkb:Q8CI65|uniprotkb:Q8VEJ5|uniprotkb:Q9CTI7|uniprotkb:Q9CWX7	psi-mi:p97493-pro_0000034151(display_long)|uniprotkb:Thioredoxin-2(gene name synonym)|uniprotkb:Txn2(gene name)|psi-mi:Txn2(display_short)	psi-mi:atpb_mouse(display_long)|uniprotkb:Atp5f1b(gene name)|psi-mi:Atp5f1b(display_short)|uniprotkb:ATP synthase F1 subunit beta(gene name synonym)|uniprotkb:Atp5b(gene name synonym)	psi-mi:"MI:0096"(pull down)	Chasapis et al. (2019)	pubmed:31018154|imex:IM-28571	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26500442|imex:IM-28571-5	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	intact:EBI-8354432(chain-parent)	interpro:IPR024034|interpro:IPR027417|interpro:IPR036121|mint:P56480|reactome:R-MMU-1268020|reactome:R-MMU-163210|reactome:R-MMU-8949613|interpro:IPR020003|ensembl:ENSMUSG00000025393(gene)|ensembl:ENSMUST00000026459(transcript)|go:"GO:0000275"("mitochondrial proton-transporting ATP synthase complex, catalytic sector F(1)")|go:"GO:0001525"(angiogenesis)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005753"(mitochondrial proton-transporting ATP synthase complex)|go:"GO:0005886"(plasma membrane)|go:"GO:0006629"(lipid metabolic process)|go:"GO:0006754"(ATP biosynthetic process)|go:"GO:0006898"(receptor-mediated endocytosis)|go:"GO:0006933"(negative regulation of cell adhesion involved in substrate-bound cell migration)|go:"GO:0009986"(cell surface)|go:"GO:0016020"(membrane)|go:"GO:0030228"(lipoprotein particle receptor activity)|go:"GO:0031966"(mitochondrial membrane)|go:"GO:0042288"(MHC class I protein binding)|go:"GO:0042645"(mitochondrial nucleoid)|go:"GO:0042776"(mitochondrial ATP synthesis coupled proton transport)|go:"GO:0043209"(myelin sheath)|go:"GO:0043531"(ADP binding)|go:"GO:0043532"(angiostatin binding)|go:"GO:0043536"(positive regulation of blood vessel endothelial cell migration)|go:"GO:0045121"(membrane raft)|go:"GO:0045259"(proton-transporting ATP synthase complex)|go:"GO:0045261"("proton-transporting ATP synthase complex, catalytic core F(1)")|go:"GO:0046034"(ATP metabolic process)|go:"GO:0046933"(proton-transporting ATP synthase activity, rotational mechanism)|go:"GO:0046961"(proton-transporting ATPase activity, rotational mechanism)|go:"GO:0051453"(regulation of intracellular pH)|go:"GO:0098761"(cellular response to interleukin-7)|go:"GO:1902600"(proton transmembrane transport)|interpro:IPR000194(ATPase, F1/V1/A1 complex, alpha/beta subunit, nucleotide-binding)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR004100(ATPase, F1/V1/A1 complex, alpha/beta subunit, N-terminal)|interpro:IPR005722(ATPase, F1 complex, beta subunit)|go:"GO:0005524"(ATP binding)|refseq:NP_058054.2	go:"GO:0005739"(mitochondrion)	chain-seq-start:60|chain-seq-end:166	-	figure legend:ST1.10|comment:DTT-eluted fraction|dataset:Rare diseases - Interactions investigated in the context of Rare genetic disease|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2020/12/04	2020/12/21	rogid:mvYK6+YgIN/WuGLBCWqsqPLfDyQ10090	rogid:ihjn7GQ1ZSBfGcfwEAYSiCIuq+410090	rigid:RFCmtElBNW02qwaB3RaUI2EVXvM	false	mutation:34-34	-	-	-	psi-mi:"MI:0082"(peptide massfingerprinting)	psi-mi:"MI:0082"(peptide massfingerprinting)
uniprotkb:P97493-PRO_0000034151	uniprotkb:Q9D051	intact:EBI-26567598	intact:EBI-773622|uniprotkb:Q3TL86|uniprotkb:Q505N8|uniprotkb:Q99LW9|ensembl:ENSMUSP00000022268	psi-mi:p97493-pro_0000034151(display_long)|uniprotkb:Thioredoxin-2(gene name synonym)|uniprotkb:Txn2(gene name)|psi-mi:Txn2(display_short)	psi-mi:odpb_mouse(display_long)|uniprotkb:Pdhb(gene name)|psi-mi:Pdhb(display_short)	psi-mi:"MI:0096"(pull down)	Chasapis et al. (2019)	pubmed:31018154|imex:IM-28571	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26500442|imex:IM-28571-5	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	intact:EBI-8354432(chain-parent)	refseq:NP_077183.1|ensembl:ENSMUSG00000021748(gene)|ensembl:ENSMUST00000022268(transcript)|go:"GO:0004739"("pyruvate dehydrogenase (acetyl-transferring) activity")|go:"GO:0005654"(nucleoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005967"(mitochondrial pyruvate dehydrogenase complex)|go:"GO:0006006"(glucose metabolic process)|go:"GO:0006086"(acetyl-CoA biosynthetic process from pyruvate)|go:"GO:0006099"(tricarboxylic acid cycle)|go:"GO:0034604"("pyruvate dehydrogenase (NAD+) activity")|go:"GO:0045254"(pyruvate dehydrogenase complex)|go:"GO:0061732"(mitochondrial acetyl-CoA biosynthetic process from pyruvate)|interpro:IPR005475(Transketolase, central region)|interpro:IPR009014(Transketolase, C-terminal/Pyruvate-ferredoxin oxidoreductase, domain II)|interpro:IPR027110|interpro:IPR029061|interpro:IPR033248|mint:Q9D051|reactome:R-MMU-204174|reactome:R-MMU-389661|reactome:R-MMU-5362517|reactome:R-MMU-70268	go:"GO:0005739"(mitochondrion)	chain-seq-start:60|chain-seq-end:166	-	figure legend:ST1.10|comment:DTT-eluted fraction|dataset:Rare diseases - Interactions investigated in the context of Rare genetic disease|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2020/12/04	2020/12/21	rogid:mvYK6+YgIN/WuGLBCWqsqPLfDyQ10090	rogid:FPts4odLhVgLVf3gEYdc9N5Wuak10090	rigid:RFCmtElBNW02qwaB3RaUI2EVXvM	false	mutation:34-34	-	-	-	psi-mi:"MI:0082"(peptide massfingerprinting)	psi-mi:"MI:0082"(peptide massfingerprinting)
uniprotkb:P97493-PRO_0000034151	uniprotkb:O08709	intact:EBI-26567598	intact:EBI-444895|uniprotkb:Q91WT2|uniprotkb:Q9QWP4|uniprotkb:Q9QWW0	psi-mi:p97493-pro_0000034151(display_long)|uniprotkb:Thioredoxin-2(gene name synonym)|uniprotkb:Txn2(gene name)|psi-mi:Txn2(display_short)	psi-mi:prdx6_mouse(display_long)|uniprotkb:Lysophosphatidylcholine acyltransferase 5(gene name synonym)|uniprotkb:Glutathione-dependent peroxiredoxin(gene name synonym)|uniprotkb:Antioxidant protein 2(gene name synonym)|uniprotkb:1-Cys peroxiredoxin(gene name synonym)|uniprotkb:Acidic calcium-independent phospholipase A2(gene name synonym)|uniprotkb:Non-selenium glutathione peroxidase(gene name synonym)|uniprotkb:Prdx6(gene name)|psi-mi:Prdx6(display_short)|uniprotkb:Aop2(gene name synonym)|uniprotkb:Ltw4(gene name synonym)|uniprotkb:Prdx5(gene name synonym)	psi-mi:"MI:0096"(pull down)	Chasapis et al. (2019)	pubmed:31018154|imex:IM-28571	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26500442|imex:IM-28571-5	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	intact:EBI-8354432(chain-parent)	refseq:NP_031479.1|interpro:IPR000866(Alkyl hydroperoxide reductase/ Thiol specific antioxidant/ Mal allergen)|interpro:IPR024706|interpro:IPR019479|go:"GO:0000302"(response to reactive oxygen species)|go:"GO:0004601"(peroxidase activity)|go:"GO:0004602"(glutathione peroxidase activity)|go:"GO:0004623"(phospholipase A2 activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005764"(lysosome)|go:"GO:0005829"(cytosol)|go:"GO:0006979"(response to oxidative stress)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032060"(bleb assembly)|go:"GO:0042744"(hydrogen peroxide catabolic process)|go:"GO:0042802"(identical protein binding)|go:"GO:0045454"(cell redox homeostasis)|go:"GO:0046475"(glycerophospholipid catabolic process)|go:"GO:0047184"(1-acylglycerophosphocholine O-acyltransferase activity)|go:"GO:0047499"(calcium-independent phospholipase A2 activity)|go:"GO:0048026"(positive regulation of mRNA splicing, via spliceosome)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051920"(peroxiredoxin activity)|go:"GO:0098869"(cellular oxidant detoxification)|go:"GO:0102567"|go:"GO:0102568"|reactome:R-MMU-3299685|reactome:R-MMU-6798695|interpro:IPR013766(Thioredoxin domain)|mint:O08709|interpro:IPR036249	go:"GO:0005739"(mitochondrion)	chain-seq-start:60|chain-seq-end:166	-	figure legend:ST1.10|comment:DTT-eluted fraction|dataset:Rare diseases - Interactions investigated in the context of Rare genetic disease|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2020/12/04	2020/12/21	rogid:mvYK6+YgIN/WuGLBCWqsqPLfDyQ10090	rogid:3Hnse2vkowtSGEobI2LJX6WrNl410090	rigid:RFCmtElBNW02qwaB3RaUI2EVXvM	false	mutation:34-34	-	-	-	psi-mi:"MI:0082"(peptide massfingerprinting)	psi-mi:"MI:0082"(peptide massfingerprinting)
uniprotkb:P97493-PRO_0000034151	uniprotkb:Q03265	intact:EBI-26567598	intact:EBI-299884|ensembl:ENSMUSP00000026495|uniprotkb:Q3TFN0|uniprotkb:Q3THN8|uniprotkb:Q3TPR0|uniprotkb:Q3TPV3|uniprotkb:Q3TZU3|uniprotkb:Q3UIR7|uniprotkb:Q543Y6	psi-mi:p97493-pro_0000034151(display_long)|uniprotkb:Thioredoxin-2(gene name synonym)|uniprotkb:Txn2(gene name)|psi-mi:Txn2(display_short)	psi-mi:atpa_mouse(display_long)|uniprotkb:Atp5f1a(gene name)|psi-mi:Atp5f1a(display_short)|uniprotkb:ATP synthase F1 subunit alpha(gene name synonym)|uniprotkb:Atp5a1(gene name synonym)	psi-mi:"MI:0096"(pull down)	Chasapis et al. (2019)	pubmed:31018154|imex:IM-28571	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26500442|imex:IM-28571-5	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	intact:EBI-8354432(chain-parent)	go:"GO:0005634"(nucleus)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005753"(mitochondrial proton-transporting ATP synthase complex)|ensembl:ENSMUSG00000025428(gene)|ensembl:ENSMUST00000026495(transcript)|go:"GO:0000275"("mitochondrial proton-transporting ATP synthase complex, catalytic sector F(1)")|go:"GO:0001937"(negative regulation of endothelial cell proliferation)|go:"GO:0002020"(protease binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005754"(mitochondrial proton-transporting ATP synthase, catalytic core)|go:"GO:0005886"(plasma membrane)|go:"GO:0006629"(lipid metabolic process)|go:"GO:0006754"(ATP biosynthetic process)|go:"GO:0008180"(COP9 signalosome)|go:"GO:0009986"(cell surface)|go:"GO:0015986"(ATP synthesis coupled proton transport)|go:"GO:0016020"(membrane)|go:"GO:0042288"(MHC class I protein binding)|go:"GO:0042776"(mitochondrial ATP synthesis coupled proton transport)|go:"GO:0043209"(myelin sheath)|go:"GO:0043531"(ADP binding)|go:"GO:0043532"(angiostatin binding)|go:"GO:0043536"(positive regulation of blood vessel endothelial cell migration)|go:"GO:0045121"(membrane raft)|go:"GO:0045259"(proton-transporting ATP synthase complex)|go:"GO:0045261"("proton-transporting ATP synthase complex, catalytic core F(1)")|go:"GO:0046034"(ATP metabolic process)|go:"GO:0046933"(proton-transporting ATP synthase activity, rotational mechanism)|interpro:IPR000194(ATPase, F1/V1/A1 complex, alpha/beta subunit, nucleotide-binding)|interpro:IPR000793(ATPase, F1/V1/A1 complex, alpha/beta subunit, C-terminal)|interpro:IPR004100(ATPase, F1/V1/A1 complex, alpha/beta subunit, N-terminal)|interpro:IPR005294(ATPase, F1 complex, alpha subunit)|interpro:IPR020003|interpro:IPR023366|interpro:IPR027417|interpro:IPR033732|interpro:IPR036121|interpro:IPR038376|mint:Q03265|reactome:R-MMU-163210|reactome:R-MMU-8949613|refseq:NP_031531.1	go:"GO:0005739"(mitochondrion)	chain-seq-start:60|chain-seq-end:166	-	figure legend:ST1.10|comment:DTT-eluted fraction|dataset:Rare diseases - Interactions investigated in the context of Rare genetic disease|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2020/12/04	2020/12/21	rogid:mvYK6+YgIN/WuGLBCWqsqPLfDyQ10090	rogid:sBPTQwqC0dJTjZlZMKRzTSu6gHg10090	rigid:RFCmtElBNW02qwaB3RaUI2EVXvM	false	mutation:34-34	-	-	-	psi-mi:"MI:0082"(peptide massfingerprinting)	psi-mi:"MI:0082"(peptide massfingerprinting)
uniprotkb:P97493-PRO_0000034151	uniprotkb:Q6ZWQ0	intact:EBI-26567598	intact:EBI-11517168|uniprotkb:Q640M5|ensembl:ENSMUSP00000047697	psi-mi:p97493-pro_0000034151(display_long)|uniprotkb:Thioredoxin-2(gene name synonym)|uniprotkb:Txn2(gene name)|psi-mi:Txn2(display_short)	psi-mi:syne2_mouse(display_long)|uniprotkb:Nuclear envelope spectrin repeat protein 2(gene name synonym)|uniprotkb:Nucleus and actin connecting element protein(gene name synonym)|uniprotkb:Synaptic nuclear envelope protein 2(gene name synonym)|uniprotkb:KASH domain-containing protein 2(gene name synonym)|uniprotkb:Syne2(gene name)|psi-mi:Syne2(display_short)	psi-mi:"MI:0096"(pull down)	Chasapis et al. (2019)	pubmed:31018154|imex:IM-28571	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26500450|imex:IM-28571-27	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	intact:EBI-8354432(chain-parent)	dip:DIP-61049N|refseq:NP_001005510.2|ensembl:ENSMUSG00000063450(gene)|ensembl:ENSMUST00000044217(transcript)|go:"GO:0003779"(actin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005640"(nuclear outer membrane)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0030016"(myofibril)|go:"GO:0030018"(Z disc)|go:"GO:0005739"(mitochondrion)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0031022"(nuclear migration along microfilament)|go:"GO:0031258"(lamellipodium membrane)|go:"GO:0005925"(focal adhesion)|go:"GO:0031527"(filopodium membrane)|go:"GO:0031965"(nuclear membrane)|go:"GO:0031981"(nuclear lumen)|go:"GO:0033017"(sarcoplasmic reticulum membrane)|go:"GO:0007097"(nuclear migration)|go:"GO:0034993"(meiotic nuclear membrane microtubule tethering complex)|go:"GO:0045111"(intermediate filament cytoskeleton)|go:"GO:0051015"(actin filament binding)|go:"GO:0051642"(centrosome localization)|go:"GO:0140444"(cytoskeleton-nuclear membrane anchor activity)|go:"GO:1902017"(regulation of cilium assembly)|interpro:IPR001589(Actinin-type, actin-binding, conserved site)|interpro:IPR001715(Calponin-like actin-binding)|interpro:IPR002017(Spectrin repeat)|interpro:IPR012315(Klarsicht/ANC-1/syne-1 homology)|interpro:IPR018159|go:"GO:0016021"(integral component of membrane)|go:"GO:0016529"(sarcoplasmic reticulum)|go:"GO:0021817"(nucleokinesis involved in cell motility in cerebral cortex radial glia guided migration)|interpro:IPR030266|interpro:IPR036872|mint:Q6ZWQ0	go:"GO:0005739"(mitochondrion)	chain-seq-start:60|chain-seq-end:166	-	figure legend:ST1.11|comment:acid-eluted fraction|dataset:Rare diseases - Interactions investigated in the context of Rare genetic disease|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2020/12/04	2020/12/21	rogid:mvYK6+YgIN/WuGLBCWqsqPLfDyQ10090	rogid:dByvgsaISSaQdpGCQahK7a5mG2w10090	rigid:fA4EicCwoUk2UHnB9bDr8kOPfc0	false	mutation:34-34	-	-	-	psi-mi:"MI:0082"(peptide massfingerprinting)	psi-mi:"MI:0082"(peptide massfingerprinting)
uniprotkb:P97493-PRO_0000034151	uniprotkb:Q91VD9	intact:EBI-26567598	intact:EBI-772739|uniprotkb:Q3UQ73|uniprotkb:Q8BM16|ensembl:ENSMUSP00000027111|ensembl:ENSMUSP00000126621	psi-mi:p97493-pro_0000034151(display_long)|uniprotkb:Thioredoxin-2(gene name synonym)|uniprotkb:Txn2(gene name)|psi-mi:Txn2(display_short)	psi-mi:ndus1_mouse(display_long)|uniprotkb:Complex I-75kD(gene name synonym)|uniprotkb:Ndufs1(gene name)|psi-mi:Ndufs1(display_short)	psi-mi:"MI:0096"(pull down)	Chasapis et al. (2019)	pubmed:31018154|imex:IM-28571	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26500450|imex:IM-28571-27	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	intact:EBI-8354432(chain-parent)	refseq:NP_001153510.1|refseq:NP_001153511.1|refseq:NP_001153512.1|refseq:NP_663493.2|refseq:XP_006496015.1|ensembl:ENSMUSG00000025968(gene)|ensembl:ENSMUST00000027111(transcript)|ensembl:ENSMUST00000168099(transcript)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005747"(mitochondrial respiratory chain complex I)|go:"GO:0005758"(mitochondrial intermembrane space)|go:"GO:0006120"(mitochondrial electron transport, NADH to ubiquinone)|go:"GO:0008137"("NADH dehydrogenase (ubiquinone) activity")|go:"GO:0008637"(apoptotic mitochondrial changes)|go:"GO:0009055"(electron transfer activity)|go:"GO:0032981"(mitochondrial respiratory chain complex I assembly)|go:"GO:0043209"(myelin sheath)|go:"GO:0045333"(cellular respiration)|go:"GO:0046034"(ATP metabolic process)|go:"GO:0046872"(metal ion binding)|go:"GO:0051537"(2 iron, 2 sulfur cluster binding)|go:"GO:0051539"(4 iron, 4 sulfur cluster binding)|go:"GO:0051881"(regulation of mitochondrial membrane potential)|go:"GO:0072593"(reactive oxygen species metabolic process)|interpro:IPR000283(NADH dehydrogenase 75 kDa subunit, conserved site)|interpro:IPR001041(Ferredoxin)|interpro:IPR006656(Molybdopterin oxidoreductase)|interpro:IPR006963(Molybdopterin oxidoreductase Fe4S4 region)|interpro:IPR010228(NADH-quinone oxidoreductase, chain G)|interpro:IPR015405(NADH-quinone oxidoreductase, chain G, C-terminal)|interpro:IPR019574|interpro:IPR036010|mint:Q91VD9|rcsb pdb:6G2J|rcsb pdb:6G72|rcsb pdb:6ZR2|rcsb pdb:6ZTQ|rcsb pdb:7AK5|rcsb pdb:7AK6|rcsb pdb:7B93|reactome:R-MMU-611105|reactome:R-MMU-6799198	go:"GO:0005739"(mitochondrion)	chain-seq-start:60|chain-seq-end:166	-	figure legend:ST1.11|comment:acid-eluted fraction|dataset:Rare diseases - Interactions investigated in the context of Rare genetic disease|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2020/12/04	2020/12/21	rogid:mvYK6+YgIN/WuGLBCWqsqPLfDyQ10090	rogid:/akd0DjF9D063ihVFyTA0+Q0gJQ10090	rigid:fA4EicCwoUk2UHnB9bDr8kOPfc0	false	mutation:34-34	-	-	-	psi-mi:"MI:0082"(peptide massfingerprinting)	psi-mi:"MI:0082"(peptide massfingerprinting)
uniprotkb:P97493-PRO_0000034151	uniprotkb:Q62425	intact:EBI-26567598	intact:EBI-299572|ensembl:ENSMUSP00000144932|ensembl:ENSMUSP00000145413|uniprotkb:Q9CQP6	psi-mi:p97493-pro_0000034151(display_long)|uniprotkb:Thioredoxin-2(gene name synonym)|uniprotkb:Txn2(gene name)|psi-mi:Txn2(display_short)	psi-mi:ndua4_mouse(display_long)|uniprotkb:Ndufa4(gene name)|psi-mi:Ndufa4(display_short)	psi-mi:"MI:0096"(pull down)	Chasapis et al. (2019)	pubmed:31018154|imex:IM-28571	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26500450|imex:IM-28571-27	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	intact:EBI-8354432(chain-parent)	ensembl:ENSMUSG00000029632(gene)|ensembl:ENSMUST00000204714(transcript)|ensembl:ENSMUST00000204978(transcript)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005747"(mitochondrial respiratory chain complex I)|go:"GO:0005751"(mitochondrial respiratory chain complex IV)|go:"GO:0022900"(electron transport chain)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:1902600"(proton transmembrane transport)|go:"GO:1904960"(positive regulation of cytochrome-c oxidase activity)|interpro:IPR010530(B12D)|mint:Q62425|rcsb pdb:1LEG|rcsb pdb:1LEK|rcsb pdb:1MWA|rcsb pdb:2CKB|reactome:R-MMU-5628897|reactome:R-MMU-611105|reactome:R-MMU-9707564|refseq:NP_035016.1	go:"GO:0005739"(mitochondrion)	chain-seq-start:60|chain-seq-end:166	-	figure legend:ST1.11|comment:acid-eluted fraction|dataset:Rare diseases - Interactions investigated in the context of Rare genetic disease|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2020/12/04	2020/12/21	rogid:mvYK6+YgIN/WuGLBCWqsqPLfDyQ10090	rogid:jHsaW6CL4Rm/cNbZXlwU02m7dlE10090	rigid:fA4EicCwoUk2UHnB9bDr8kOPfc0	false	mutation:34-34	-	-	-	psi-mi:"MI:0082"(peptide massfingerprinting)	psi-mi:"MI:0082"(peptide massfingerprinting)
uniprotkb:P97493-PRO_0000034151	uniprotkb:Q5M8R7	intact:EBI-26567598	intact:EBI-26500712	psi-mi:p97493-pro_0000034151(display_long)|uniprotkb:Thioredoxin-2(gene name synonym)|uniprotkb:Txn2(gene name)|psi-mi:Txn2(display_short)	psi-mi:q5m8r7_mouse(display_long)|uniprotkb:Ldhb(gene name)|psi-mi:Ldhb(display_short)|uniprotkb:Ldh2(gene name synonym)	psi-mi:"MI:0096"(pull down)	Chasapis et al. (2019)	pubmed:31018154|imex:IM-28571	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26500450|imex:IM-28571-27	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	intact:EBI-8354432(chain-parent)	go:"GO:0016616"(oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor)|go:"GO:0005975"(carbohydrate metabolic process)|mint:Q5M8R7|interpro:IPR022383|interpro:IPR015955(Lactate dehydrogenase/glycoside hydrolase, family 4, C-terminal)	go:"GO:0005739"(mitochondrion)	chain-seq-start:60|chain-seq-end:166	-	figure legend:ST1.11|comment:acid-eluted fraction|dataset:Rare diseases - Interactions investigated in the context of Rare genetic disease|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2020/12/04	2020/12/21	rogid:mvYK6+YgIN/WuGLBCWqsqPLfDyQ10090	rogid:yu4USj856rcxI/VFAxvXtMsD0hQ10090	rigid:fA4EicCwoUk2UHnB9bDr8kOPfc0	false	mutation:34-34	-	-	-	psi-mi:"MI:0082"(peptide massfingerprinting)	psi-mi:"MI:0082"(peptide massfingerprinting)
uniprotkb:P97493-PRO_0000034151	uniprotkb:Q9JHV3	intact:EBI-26567598	intact:EBI-26500700	psi-mi:p97493-pro_0000034151(display_long)|uniprotkb:Thioredoxin-2(gene name synonym)|uniprotkb:Txn2(gene name)|psi-mi:Txn2(display_short)	psi-mi:q9jhv3_mouse(display_long)|uniprotkb:Klra19(gene name)|psi-mi:Klra19(display_short)	psi-mi:"MI:0096"(pull down)	Chasapis et al. (2019)	pubmed:31018154|imex:IM-28571	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26500450|imex:IM-28571-27	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	intact:EBI-8354432(chain-parent)	go:"GO:0005886"(plasma membrane)|go:"GO:0016021"(integral component of membrane)|mint:Q9JHV3|refseq:NP_444384.1|interpro:IPR001304(C-type lectin)|interpro:IPR016186(C-type lectin-like)|interpro:IPR016187(C-type lectin fold)|interpro:IPR013600(Ly49-like N-terminal)|interpro:IPR033992	go:"GO:0005739"(mitochondrion)	chain-seq-start:60|chain-seq-end:166	-	figure legend:ST1.11|comment:acid-eluted fraction|dataset:Rare diseases - Interactions investigated in the context of Rare genetic disease|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2020/12/04	2020/12/21	rogid:mvYK6+YgIN/WuGLBCWqsqPLfDyQ10090	rogid:9Vj0O+zXQo7LEwj2bMtU6IlIEQ810090	rigid:fA4EicCwoUk2UHnB9bDr8kOPfc0	false	mutation:34-34	-	-	-	psi-mi:"MI:0082"(peptide massfingerprinting)	psi-mi:"MI:0082"(peptide massfingerprinting)
uniprotkb:P97493-PRO_0000034151	uniprotkb:Q03265	intact:EBI-26567598	intact:EBI-299884|ensembl:ENSMUSP00000026495|uniprotkb:Q3TFN0|uniprotkb:Q3THN8|uniprotkb:Q3TPR0|uniprotkb:Q3TPV3|uniprotkb:Q3TZU3|uniprotkb:Q3UIR7|uniprotkb:Q543Y6	psi-mi:p97493-pro_0000034151(display_long)|uniprotkb:Thioredoxin-2(gene name synonym)|uniprotkb:Txn2(gene name)|psi-mi:Txn2(display_short)	psi-mi:atpa_mouse(display_long)|uniprotkb:Atp5f1a(gene name)|psi-mi:Atp5f1a(display_short)|uniprotkb:ATP synthase F1 subunit alpha(gene name synonym)|uniprotkb:Atp5a1(gene name synonym)	psi-mi:"MI:0096"(pull down)	Chasapis et al. (2019)	pubmed:31018154|imex:IM-28571	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26500450|imex:IM-28571-27	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	intact:EBI-8354432(chain-parent)	go:"GO:0005634"(nucleus)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005753"(mitochondrial proton-transporting ATP synthase complex)|ensembl:ENSMUSG00000025428(gene)|ensembl:ENSMUST00000026495(transcript)|go:"GO:0000275"("mitochondrial proton-transporting ATP synthase complex, catalytic sector F(1)")|go:"GO:0001937"(negative regulation of endothelial cell proliferation)|go:"GO:0002020"(protease binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005754"(mitochondrial proton-transporting ATP synthase, catalytic core)|go:"GO:0005886"(plasma membrane)|go:"GO:0006629"(lipid metabolic process)|go:"GO:0006754"(ATP biosynthetic process)|go:"GO:0008180"(COP9 signalosome)|go:"GO:0009986"(cell surface)|go:"GO:0015986"(ATP synthesis coupled proton transport)|go:"GO:0016020"(membrane)|go:"GO:0042288"(MHC class I protein binding)|go:"GO:0042776"(mitochondrial ATP synthesis coupled proton transport)|go:"GO:0043209"(myelin sheath)|go:"GO:0043531"(ADP binding)|go:"GO:0043532"(angiostatin binding)|go:"GO:0043536"(positive regulation of blood vessel endothelial cell migration)|go:"GO:0045121"(membrane raft)|go:"GO:0045259"(proton-transporting ATP synthase complex)|go:"GO:0045261"("proton-transporting ATP synthase complex, catalytic core F(1)")|go:"GO:0046034"(ATP metabolic process)|go:"GO:0046933"(proton-transporting ATP synthase activity, rotational mechanism)|interpro:IPR000194(ATPase, F1/V1/A1 complex, alpha/beta subunit, nucleotide-binding)|interpro:IPR000793(ATPase, F1/V1/A1 complex, alpha/beta subunit, C-terminal)|interpro:IPR004100(ATPase, F1/V1/A1 complex, alpha/beta subunit, N-terminal)|interpro:IPR005294(ATPase, F1 complex, alpha subunit)|interpro:IPR020003|interpro:IPR023366|interpro:IPR027417|interpro:IPR033732|interpro:IPR036121|interpro:IPR038376|mint:Q03265|reactome:R-MMU-163210|reactome:R-MMU-8949613|refseq:NP_031531.1	go:"GO:0005739"(mitochondrion)	chain-seq-start:60|chain-seq-end:166	-	figure legend:ST1.11|comment:acid-eluted fraction|dataset:Rare diseases - Interactions investigated in the context of Rare genetic disease|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2020/12/04	2020/12/21	rogid:mvYK6+YgIN/WuGLBCWqsqPLfDyQ10090	rogid:sBPTQwqC0dJTjZlZMKRzTSu6gHg10090	rigid:fA4EicCwoUk2UHnB9bDr8kOPfc0	false	mutation:34-34	-	-	-	psi-mi:"MI:0082"(peptide massfingerprinting)	psi-mi:"MI:0082"(peptide massfingerprinting)
uniprotkb:P97493-PRO_0000034151	uniprotkb:E9Q851	intact:EBI-26567598	intact:EBI-26500762|ensembl:ENSMUSP00000128892	psi-mi:p97493-pro_0000034151(display_long)|uniprotkb:Thioredoxin-2(gene name synonym)|uniprotkb:Txn2(gene name)|psi-mi:Txn2(display_short)	psi-mi:e9q851_mouse(display_long)|uniprotkb:Racgap1(gene name)|psi-mi:Racgap1(display_short)	psi-mi:"MI:0096"(pull down)	Chasapis et al. (2019)	pubmed:31018154|imex:IM-28571	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26500458|imex:IM-28571-29	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	intact:EBI-8354432(chain-parent)	ensembl:ENSMUSG00000023015(gene)|ensembl:ENSMUST00000171908(transcript)|mint:E9Q851	go:"GO:0005739"(mitochondrion)	chain-seq-start:60|chain-seq-end:166	-	figure legend:ST1.12|comment:DTT-eluted fraction|dataset:Rare diseases - Interactions investigated in the context of Rare genetic disease|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2020/12/04	2020/12/21	rogid:mvYK6+YgIN/WuGLBCWqsqPLfDyQ10090	rogid:678RDy8BvYcwYkmNlK7PmEMr6G010090	rigid:imMV24ckIa0Ur88+jDyNTwiO3Qk	false	mutation:34-34	-	-	-	psi-mi:"MI:0082"(peptide massfingerprinting)	psi-mi:"MI:0082"(peptide massfingerprinting)
uniprotkb:P97493-PRO_0000034151	uniprotkb:Q8BIL4	intact:EBI-26567598	intact:EBI-26500756	psi-mi:p97493-pro_0000034151(display_long)|uniprotkb:Thioredoxin-2(gene name synonym)|uniprotkb:Txn2(gene name)|psi-mi:Txn2(display_short)	psi-mi:q8bil4_mouse(display_long)|uniprotkb:Zfp809(gene name)|psi-mi:Zfp809(display_short)|uniprotkb:BB114266(gene name synonym)	psi-mi:"MI:0096"(pull down)	Chasapis et al. (2019)	pubmed:31018154|imex:IM-28571	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26500458|imex:IM-28571-29	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	intact:EBI-8354432(chain-parent)	mint:Q8BIL4|interpro:IPR039938	go:"GO:0005739"(mitochondrion)	chain-seq-start:60|chain-seq-end:166	-	figure legend:ST1.12|comment:DTT-eluted fraction|dataset:Rare diseases - Interactions investigated in the context of Rare genetic disease|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2020/12/04	2020/12/21	rogid:mvYK6+YgIN/WuGLBCWqsqPLfDyQ10090	rogid:+Ze1Y9U15omsJCCmugHhoTpQYA010090	rigid:imMV24ckIa0Ur88+jDyNTwiO3Qk	false	mutation:34-34	-	-	-	psi-mi:"MI:0082"(peptide massfingerprinting)	psi-mi:"MI:0082"(peptide massfingerprinting)
uniprotkb:P97493-PRO_0000034151	uniprotkb:Q3UWR0	intact:EBI-26567598	intact:EBI-26500748	psi-mi:p97493-pro_0000034151(display_long)|uniprotkb:Thioredoxin-2(gene name synonym)|uniprotkb:Txn2(gene name)|psi-mi:Txn2(display_short)	psi-mi:q3uwr0_mouse(display_long)|uniprotkb:Dnmt3a(gene name)|psi-mi:Dnmt3a(display_short)	psi-mi:"MI:0096"(pull down)	Chasapis et al. (2019)	pubmed:31018154|imex:IM-28571	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26500458|imex:IM-28571-29	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	intact:EBI-8354432(chain-parent)	go:"GO:0009008"(DNA-methyltransferase activity)|go:"GO:0010468"(regulation of gene expression)|mint:Q3UWR0|interpro:IPR030487|interpro:IPR000313(PWWP)	go:"GO:0005739"(mitochondrion)	chain-seq-start:60|chain-seq-end:166	-	figure legend:ST1.12|comment:DTT-eluted fraction|dataset:Rare diseases - Interactions investigated in the context of Rare genetic disease|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2020/12/04	2020/12/21	rogid:mvYK6+YgIN/WuGLBCWqsqPLfDyQ10090	rogid:FgPWqlJ+ZlEY+fcWFMen6zcPGPo10090	rigid:imMV24ckIa0Ur88+jDyNTwiO3Qk	false	mutation:34-34	-	-	-	psi-mi:"MI:0082"(peptide massfingerprinting)	psi-mi:"MI:0082"(peptide massfingerprinting)
uniprotkb:P97493-PRO_0000034151	uniprotkb:B1AQ77	intact:EBI-26567598	intact:EBI-4283738|ensembl:ENSMUSP00000103034	psi-mi:p97493-pro_0000034151(display_long)|uniprotkb:Thioredoxin-2(gene name synonym)|uniprotkb:Txn2(gene name)|psi-mi:Txn2(display_short)	psi-mi:b1aq77_mouse(display_long)|uniprotkb:Krt15(gene name)|psi-mi:Krt15(display_short)	psi-mi:"MI:0096"(pull down)	Chasapis et al. (2019)	pubmed:31018154|imex:IM-28571	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26500458|imex:IM-28571-29	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	intact:EBI-8354432(chain-parent)	refseq:NP_032495.2|ensembl:ENSMUSG00000054146(gene)|ensembl:ENSMUST00000107411(transcript)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005882"(intermediate filament)|go:"GO:0097110"(scaffold protein binding)|interpro:IPR002957(Keratin, type I)|interpro:IPR018039|interpro:IPR039008|mint:B1AQ77	go:"GO:0005739"(mitochondrion)	chain-seq-start:60|chain-seq-end:166	-	figure legend:ST1.12|comment:DTT-eluted fraction|dataset:Rare diseases - Interactions investigated in the context of Rare genetic disease|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2020/12/04	2020/12/21	rogid:mvYK6+YgIN/WuGLBCWqsqPLfDyQ10090	rogid:1UXzTf4nv5xlyEKtZjxS95LwehE10090	rigid:imMV24ckIa0Ur88+jDyNTwiO3Qk	false	mutation:34-34	-	-	-	psi-mi:"MI:0082"(peptide massfingerprinting)	psi-mi:"MI:0082"(peptide massfingerprinting)
uniprotkb:P97493-PRO_0000034151	uniprotkb:Q8R1X5	intact:EBI-26567598	intact:EBI-26500744	psi-mi:p97493-pro_0000034151(display_long)|uniprotkb:Thioredoxin-2(gene name synonym)|uniprotkb:Txn2(gene name)|psi-mi:Txn2(display_short)	psi-mi:q8r1x5_mouse(display_long)|uniprotkb:Edem3(gene name)|psi-mi:Edem3(display_short)	psi-mi:"MI:0096"(pull down)	Chasapis et al. (2019)	pubmed:31018154|imex:IM-28571	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26500458|imex:IM-28571-29	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	intact:EBI-8354432(chain-parent)	mint:Q8R1X5	go:"GO:0005739"(mitochondrion)	chain-seq-start:60|chain-seq-end:166	-	figure legend:ST1.12|comment:DTT-eluted fraction|dataset:Rare diseases - Interactions investigated in the context of Rare genetic disease|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2020/12/04	2020/12/21	rogid:mvYK6+YgIN/WuGLBCWqsqPLfDyQ10090	rogid:87HmRKTR0fHMqQWK39OJwwLBqVc10090	rigid:imMV24ckIa0Ur88+jDyNTwiO3Qk	false	mutation:34-34	-	-	-	psi-mi:"MI:0082"(peptide massfingerprinting)	psi-mi:"MI:0082"(peptide massfingerprinting)
uniprotkb:P97493-PRO_0000034151	uniprotkb:P56480	intact:EBI-26567598	intact:EBI-299482|ensembl:ENSMUSP00000026459|uniprotkb:Q0QEP4|uniprotkb:Q3TFD7|uniprotkb:Q3TIP9|uniprotkb:Q3TK44|uniprotkb:Q3TWD5|uniprotkb:Q3TX28|uniprotkb:Q3U6U4|uniprotkb:Q3U774|uniprotkb:Q3UB69|uniprotkb:Q3UF69|uniprotkb:Q8CI65|uniprotkb:Q8VEJ5|uniprotkb:Q9CTI7|uniprotkb:Q9CWX7	psi-mi:p97493-pro_0000034151(display_long)|uniprotkb:Thioredoxin-2(gene name synonym)|uniprotkb:Txn2(gene name)|psi-mi:Txn2(display_short)	psi-mi:atpb_mouse(display_long)|uniprotkb:Atp5f1b(gene name)|psi-mi:Atp5f1b(display_short)|uniprotkb:ATP synthase F1 subunit beta(gene name synonym)|uniprotkb:Atp5b(gene name synonym)	psi-mi:"MI:0096"(pull down)	Chasapis et al. (2019)	pubmed:31018154|imex:IM-28571	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26500458|imex:IM-28571-29	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	intact:EBI-8354432(chain-parent)	interpro:IPR024034|interpro:IPR027417|interpro:IPR036121|mint:P56480|reactome:R-MMU-1268020|reactome:R-MMU-163210|reactome:R-MMU-8949613|interpro:IPR020003|ensembl:ENSMUSG00000025393(gene)|ensembl:ENSMUST00000026459(transcript)|go:"GO:0000275"("mitochondrial proton-transporting ATP synthase complex, catalytic sector F(1)")|go:"GO:0001525"(angiogenesis)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005753"(mitochondrial proton-transporting ATP synthase complex)|go:"GO:0005886"(plasma membrane)|go:"GO:0006629"(lipid metabolic process)|go:"GO:0006754"(ATP biosynthetic process)|go:"GO:0006898"(receptor-mediated endocytosis)|go:"GO:0006933"(negative regulation of cell adhesion involved in substrate-bound cell migration)|go:"GO:0009986"(cell surface)|go:"GO:0016020"(membrane)|go:"GO:0030228"(lipoprotein particle receptor activity)|go:"GO:0031966"(mitochondrial membrane)|go:"GO:0042288"(MHC class I protein binding)|go:"GO:0042645"(mitochondrial nucleoid)|go:"GO:0042776"(mitochondrial ATP synthesis coupled proton transport)|go:"GO:0043209"(myelin sheath)|go:"GO:0043531"(ADP binding)|go:"GO:0043532"(angiostatin binding)|go:"GO:0043536"(positive regulation of blood vessel endothelial cell migration)|go:"GO:0045121"(membrane raft)|go:"GO:0045259"(proton-transporting ATP synthase complex)|go:"GO:0045261"("proton-transporting ATP synthase complex, catalytic core F(1)")|go:"GO:0046034"(ATP metabolic process)|go:"GO:0046933"(proton-transporting ATP synthase activity, rotational mechanism)|go:"GO:0046961"(proton-transporting ATPase activity, rotational mechanism)|go:"GO:0051453"(regulation of intracellular pH)|go:"GO:0098761"(cellular response to interleukin-7)|go:"GO:1902600"(proton transmembrane transport)|interpro:IPR000194(ATPase, F1/V1/A1 complex, alpha/beta subunit, nucleotide-binding)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR004100(ATPase, F1/V1/A1 complex, alpha/beta subunit, N-terminal)|interpro:IPR005722(ATPase, F1 complex, beta subunit)|go:"GO:0005524"(ATP binding)|refseq:NP_058054.2	go:"GO:0005739"(mitochondrion)	chain-seq-start:60|chain-seq-end:166	-	figure legend:ST1.12|comment:DTT-eluted fraction|dataset:Rare diseases - Interactions investigated in the context of Rare genetic disease|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2020/12/04	2020/12/21	rogid:mvYK6+YgIN/WuGLBCWqsqPLfDyQ10090	rogid:ihjn7GQ1ZSBfGcfwEAYSiCIuq+410090	rigid:imMV24ckIa0Ur88+jDyNTwiO3Qk	false	mutation:34-34	-	-	-	psi-mi:"MI:0082"(peptide massfingerprinting)	psi-mi:"MI:0082"(peptide massfingerprinting)
uniprotkb:P97493-PRO_0000034151	uniprotkb:D6RJ85	intact:EBI-26567598	intact:EBI-26500790|ensembl:ENSMUSP00000121603	psi-mi:p97493-pro_0000034151(display_long)|uniprotkb:Thioredoxin-2(gene name synonym)|uniprotkb:Txn2(gene name)|psi-mi:Txn2(display_short)	psi-mi:d6rj85_mouse(display_long)|uniprotkb:Rbm39(gene name)|psi-mi:Rbm39(display_short)	psi-mi:"MI:0096"(pull down)	Chasapis et al. (2019)	pubmed:31018154|imex:IM-28571	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26500466|imex:IM-28571-45	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	intact:EBI-8354432(chain-parent)	ensembl:ENSMUSG00000027620(gene)|ensembl:ENSMUST00000154677(transcript)|mint:D6RJ85	go:"GO:0005739"(mitochondrion)	chain-seq-start:60|chain-seq-end:166	-	figure legend:ST1.13|comment:DTT-eluted fraction|dataset:Rare diseases - Interactions investigated in the context of Rare genetic disease|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2020/12/04	2020/12/21	rogid:mvYK6+YgIN/WuGLBCWqsqPLfDyQ10090	rogid:Huq2IdhNzrbR489SBotGSjD7rb010090	rigid:VXXgzqd9VT6zc4m2iXaha5Bth8o	false	mutation:34-34	-	-	-	psi-mi:"MI:0082"(peptide massfingerprinting)	psi-mi:"MI:0082"(peptide massfingerprinting)
uniprotkb:P97493-PRO_0000034151	uniprotkb:Q8R429	intact:EBI-26567598	intact:EBI-25640828|ensembl:ENSMUSP00000032974	psi-mi:p97493-pro_0000034151(display_long)|uniprotkb:Thioredoxin-2(gene name synonym)|uniprotkb:Txn2(gene name)|psi-mi:Txn2(display_short)	psi-mi:at2a1_mouse(display_long)|uniprotkb:Atp2a1(gene name)|psi-mi:Atp2a1(display_short)|uniprotkb:Calcium pump 1(gene name synonym)|uniprotkb:Calcium-transporting ATPase sarcoplasmic reticulum type, fast twitch skeletal muscle isoform(gene name synonym)|uniprotkb:"Endoplasmic reticulum class 1/2 Ca(2+) ATPase"(gene name synonym)	psi-mi:"MI:0096"(pull down)	Chasapis et al. (2019)	pubmed:31018154|imex:IM-28571	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26500466|imex:IM-28571-45	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	intact:EBI-8354432(chain-parent)	ensembl:ENSMUSG00000030730(gene)|ensembl:ENSMUST00000032974(transcript)|go:"GO:0005338"(nucleotide-sugar transmembrane transporter activity)|go:"GO:0005388"(P-type calcium transporter activity)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005739"(mitochondrion)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005793"(endoplasmic reticulum-Golgi intermediate compartment)|go:"GO:0006816"(calcium ion transport)|go:"GO:0006874"(cellular calcium ion homeostasis)|go:"GO:0006937"(regulation of muscle contraction)|go:"GO:0006942"(regulation of striated muscle contraction)|go:"GO:0008553"(P-type proton-exporting transporter activity)|go:"GO:0008637"(apoptotic mitochondrial changes)|go:"GO:0016020"(membrane)|go:"GO:0016529"(sarcoplasmic reticulum)|go:"GO:0030899"(calcium-dependent ATPase activity)|go:"GO:0031448"(positive regulation of fast-twitch skeletal muscle fiber contraction)|go:"GO:0031673"(H zone)|go:"GO:0031674"(I band)|go:"GO:0032470"(positive regulation of endoplasmic reticulum calcium ion concentration)|go:"GO:0032471"(negative regulation of endoplasmic reticulum calcium ion concentration)|go:"GO:0033017"(sarcoplasmic reticulum membrane)|go:"GO:0034976"(response to endoplasmic reticulum stress)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0043434"(response to peptide hormone)|go:"GO:0045988"(negative regulation of striated muscle contraction)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051561"(positive regulation of mitochondrial calcium ion concentration)|go:"GO:0051659"(maintenance of mitochondrion location)|go:"GO:0070059"(intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress)|go:"GO:0070296"(sarcoplasmic reticulum calcium ion transport)|go:"GO:0070509"(calcium ion import)|go:"GO:0070588"(calcium ion transmembrane transport)|go:"GO:0090076"(relaxation of skeletal muscle)|go:"GO:0106134"(positive regulation of cardiac muscle cell contraction)|go:"GO:0016021"(integral component of membrane)|go:"GO:1901896"(positive regulation of ATPase-coupled calcium transmembrane transporter activity)|go:"GO:1902082"(positive regulation of calcium ion import into sarcoplasmic reticulum)|go:"GO:1990036"(calcium ion import into sarcoplasmic reticulum)|interpro:IPR001757(ATPase, P-type, K/Mg/Cd/Cu/Zn/Na/Ca/Na/H-transporter)|interpro:IPR004014(ATPase, P-type cation-transporter, N-terminal)|interpro:IPR005782(Calcium ATPase)|interpro:IPR006068(ATPase, P-type cation-transporter, C-terminal)|interpro:IPR008250(E1-E2 ATPase-associated region)|interpro:IPR023214|interpro:IPR023298|interpro:IPR023299|interpro:IPR036412|interpro:IPR044492|mint:Q8R429|reactome:R-MMU-418359|reactome:R-MMU-5578775|reactome:R-MMU-936837|interpro:IPR018303|refseq:NP_031530.2	go:"GO:0005739"(mitochondrion)	chain-seq-start:60|chain-seq-end:166	-	figure legend:ST1.13|comment:DTT-eluted fraction|dataset:Rare diseases - Interactions investigated in the context of Rare genetic disease|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2020/12/04	2020/12/21	rogid:mvYK6+YgIN/WuGLBCWqsqPLfDyQ10090	rogid:cNZxY+Ktdq8N/mfssZfFrTwqZQ010090	rigid:VXXgzqd9VT6zc4m2iXaha5Bth8o	false	mutation:34-34	-	-	-	psi-mi:"MI:0082"(peptide massfingerprinting)	psi-mi:"MI:0082"(peptide massfingerprinting)
uniprotkb:P97493-PRO_0000034151	uniprotkb:B1AQ77	intact:EBI-26567598	intact:EBI-4283738|ensembl:ENSMUSP00000103034	psi-mi:p97493-pro_0000034151(display_long)|uniprotkb:Thioredoxin-2(gene name synonym)|uniprotkb:Txn2(gene name)|psi-mi:Txn2(display_short)	psi-mi:b1aq77_mouse(display_long)|uniprotkb:Krt15(gene name)|psi-mi:Krt15(display_short)	psi-mi:"MI:0096"(pull down)	Chasapis et al. (2019)	pubmed:31018154|imex:IM-28571	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26500466|imex:IM-28571-45	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	intact:EBI-8354432(chain-parent)	refseq:NP_032495.2|ensembl:ENSMUSG00000054146(gene)|ensembl:ENSMUST00000107411(transcript)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005882"(intermediate filament)|go:"GO:0097110"(scaffold protein binding)|interpro:IPR002957(Keratin, type I)|interpro:IPR018039|interpro:IPR039008|mint:B1AQ77	go:"GO:0005739"(mitochondrion)	chain-seq-start:60|chain-seq-end:166	-	figure legend:ST1.13|comment:DTT-eluted fraction|dataset:Rare diseases - Interactions investigated in the context of Rare genetic disease|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2020/12/04	2020/12/21	rogid:mvYK6+YgIN/WuGLBCWqsqPLfDyQ10090	rogid:1UXzTf4nv5xlyEKtZjxS95LwehE10090	rigid:VXXgzqd9VT6zc4m2iXaha5Bth8o	false	mutation:34-34	-	-	-	psi-mi:"MI:0082"(peptide massfingerprinting)	psi-mi:"MI:0082"(peptide massfingerprinting)
uniprotkb:P97493-PRO_0000034151	uniprotkb:Q03265	intact:EBI-26567598	intact:EBI-299884|ensembl:ENSMUSP00000026495|uniprotkb:Q3TFN0|uniprotkb:Q3THN8|uniprotkb:Q3TPR0|uniprotkb:Q3TPV3|uniprotkb:Q3TZU3|uniprotkb:Q3UIR7|uniprotkb:Q543Y6	psi-mi:p97493-pro_0000034151(display_long)|uniprotkb:Thioredoxin-2(gene name synonym)|uniprotkb:Txn2(gene name)|psi-mi:Txn2(display_short)	psi-mi:atpa_mouse(display_long)|uniprotkb:Atp5f1a(gene name)|psi-mi:Atp5f1a(display_short)|uniprotkb:ATP synthase F1 subunit alpha(gene name synonym)|uniprotkb:Atp5a1(gene name synonym)	psi-mi:"MI:0096"(pull down)	Chasapis et al. (2019)	pubmed:31018154|imex:IM-28571	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26500466|imex:IM-28571-45	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	intact:EBI-8354432(chain-parent)	go:"GO:0005634"(nucleus)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005753"(mitochondrial proton-transporting ATP synthase complex)|ensembl:ENSMUSG00000025428(gene)|ensembl:ENSMUST00000026495(transcript)|go:"GO:0000275"("mitochondrial proton-transporting ATP synthase complex, catalytic sector F(1)")|go:"GO:0001937"(negative regulation of endothelial cell proliferation)|go:"GO:0002020"(protease binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005754"(mitochondrial proton-transporting ATP synthase, catalytic core)|go:"GO:0005886"(plasma membrane)|go:"GO:0006629"(lipid metabolic process)|go:"GO:0006754"(ATP biosynthetic process)|go:"GO:0008180"(COP9 signalosome)|go:"GO:0009986"(cell surface)|go:"GO:0015986"(ATP synthesis coupled proton transport)|go:"GO:0016020"(membrane)|go:"GO:0042288"(MHC class I protein binding)|go:"GO:0042776"(mitochondrial ATP synthesis coupled proton transport)|go:"GO:0043209"(myelin sheath)|go:"GO:0043531"(ADP binding)|go:"GO:0043532"(angiostatin binding)|go:"GO:0043536"(positive regulation of blood vessel endothelial cell migration)|go:"GO:0045121"(membrane raft)|go:"GO:0045259"(proton-transporting ATP synthase complex)|go:"GO:0045261"("proton-transporting ATP synthase complex, catalytic core F(1)")|go:"GO:0046034"(ATP metabolic process)|go:"GO:0046933"(proton-transporting ATP synthase activity, rotational mechanism)|interpro:IPR000194(ATPase, F1/V1/A1 complex, alpha/beta subunit, nucleotide-binding)|interpro:IPR000793(ATPase, F1/V1/A1 complex, alpha/beta subunit, C-terminal)|interpro:IPR004100(ATPase, F1/V1/A1 complex, alpha/beta subunit, N-terminal)|interpro:IPR005294(ATPase, F1 complex, alpha subunit)|interpro:IPR020003|interpro:IPR023366|interpro:IPR027417|interpro:IPR033732|interpro:IPR036121|interpro:IPR038376|mint:Q03265|reactome:R-MMU-163210|reactome:R-MMU-8949613|refseq:NP_031531.1	go:"GO:0005739"(mitochondrion)	chain-seq-start:60|chain-seq-end:166	-	figure legend:ST1.13|comment:DTT-eluted fraction|dataset:Rare diseases - Interactions investigated in the context of Rare genetic disease|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2020/12/04	2020/12/21	rogid:mvYK6+YgIN/WuGLBCWqsqPLfDyQ10090	rogid:sBPTQwqC0dJTjZlZMKRzTSu6gHg10090	rigid:VXXgzqd9VT6zc4m2iXaha5Bth8o	false	mutation:34-34	-	-	-	psi-mi:"MI:0082"(peptide massfingerprinting)	psi-mi:"MI:0082"(peptide massfingerprinting)
uniprotkb:P02675	uniprotkb:Q99757-PRO_0000034150	intact:EBI-1034445|uniprotkb:A0JLR9|uniprotkb:Q32Q65|uniprotkb:Q3KPF2|uniprotkb:B2R7G3|ensembl:ENSP00000306099	intact:EBI-26565164	psi-mi:fibb_human(display_long)|uniprotkb:FGB(gene name)|psi-mi:FGB(display_short)	psi-mi:q99757-pro_0000034150(display_long)|uniprotkb:Thioredoxin-2(gene name synonym)|uniprotkb:TXN2(gene name)|psi-mi:TXN2(display_short)|uniprotkb:TRX2(gene name synonym)	psi-mi:"MI:0018"(two hybrid)	Chasapis et al. (2019)	pubmed:31018154|imex:IM-28571	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26500857|imex:IM-28571-31	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001171670.1|refseq:NP_005132.2|go:"GO:0005577"(fibrinogen complex)|go:"GO:0005615"(extracellular space)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005886"(plasma membrane)|go:"GO:0005938"(cell cortex)|go:"GO:0007155"(cell adhesion)|go:"GO:0007160"(cell-matrix adhesion)|go:"GO:0009897"(external side of plasma membrane)|go:"GO:0009986"(cell surface)|go:"GO:0031091"(platelet alpha granule)|go:"GO:0031093"(platelet alpha granule lumen)|go:"GO:0031639"(plasminogen activation)|go:"GO:0034116"(positive regulation of heterotypic cell-cell adhesion)|go:"GO:0034622"|go:"GO:0042730"(fibrinolysis)|go:"GO:0043152"(induction of bacterial agglutination)|go:"GO:0044320"(cellular response to leptin stimulus)|go:"GO:0045087"(innate immune response)|go:"GO:0045202"(synapse)|go:"GO:0045907"(positive regulation of vasoconstriction)|go:"GO:0045921"(positive regulation of exocytosis)|go:"GO:0050714"(positive regulation of protein secretion)|go:"GO:0051087"(chaperone binding)|go:"GO:0051258"(protein polymerization)|go:"GO:0051592"(response to calcium ion)|go:"GO:0062023"(collagen-containing extracellular matrix)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070374"(positive regulation of ERK1 and ERK2 cascade)|go:"GO:0070527"(platelet aggregation)|go:"GO:0071347"(cellular response to interleukin-1)|go:"GO:0072378"(blood coagulation, fibrin clot formation)|go:"GO:0072562"(blood microparticle)|go:"GO:0090277"(positive regulation of peptide hormone secretion)|go:"GO:1900026"(positive regulation of substrate adhesion-dependent cell spreading)|go:"GO:1902042"(negative regulation of extrinsic apoptotic signaling pathway via death domain receptors)|go:"GO:1903561"(extracellular vesicle)|go:"GO:2000352"(negative regulation of endothelial cell apoptotic process)|interpro:IPR002181(Fibrinogen, alpha/beta/gamma chain, C-terminal globular)|interpro:IPR012290(Fibrinogen, alpha/beta/gamma chain, coiled coil)|interpro:IPR014716(Fibrinogen, alpha/beta/gamma chain, C-terminal globular, subdomain 1)|interpro:IPR020837|interpro:IPR036056|interpro:IPR037580|mint:P02675|rcsb pdb:1FZA|rcsb pdb:1FZB|rcsb pdb:1FZC|rcsb pdb:1FZE|rcsb pdb:1FZF|rcsb pdb:1FZG|rcsb pdb:1LT9|rcsb pdb:1LTJ|rcsb pdb:1N86|rcsb pdb:1N8E|rcsb pdb:1RE3|rcsb pdb:1RE4|rcsb pdb:1RF0|rcsb pdb:1RF1|rcsb pdb:2A45|rcsb pdb:2FFD|rcsb pdb:2H43|rcsb pdb:2HLO|rcsb pdb:2HOD|rcsb pdb:2HPC|rcsb pdb:2OYH|rcsb pdb:2OYI|rcsb pdb:2Q9I|rcsb pdb:2XNX|rcsb pdb:2XNY|rcsb pdb:2Z4E|rcsb pdb:3BVH|rcsb pdb:3E1I|rcsb pdb:3GHG|rcsb pdb:3H32|rcsb pdb:3HUS|rcsb pdb:6ATZ|rcsb pdb:6BIJ|rcsb pdb:6BIL|rcsb pdb:6V0Y|rcsb pdb:6V13|rcsb pdb:6V15|rcsb pdb:6V18|rcsb pdb:6V19|rcsb pdb:6V1A|reactome:R-HSA-114608|reactome:R-HSA-1236974|reactome:R-HSA-140875|reactome:R-HSA-166058|reactome:R-HSA-216083|reactome:R-HSA-354192|reactome:R-HSA-354194|reactome:R-HSA-372708|reactome:R-HSA-5602498|reactome:R-HSA-5603041|reactome:R-HSA-5674135|reactome:R-HSA-5686938|reactome:R-HSA-6802946|ensembl:ENSG00000171564(gene)|ensembl:ENST00000302068(transcript)|go:"GO:0002250"(adaptive immune response)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005201"(extracellular matrix structural constituent)|go:"GO:0005576"(extracellular region)|reactome:R-HSA-6802955|reactome:R-HSA-9649948|reactome:R-HSA-9656223|reactome:R-HSA-6802952|reactome:R-HSA-6802948|dip:DIP-385N	intact:EBI-2932492(chain-parent)	-	-	chain-seq-start:60|chain-seq-end:166	figure legend:ST2.2|dataset:Rare diseases - Interactions investigated in the context of Rare genetic disease|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	-	2020/12/04	2020/12/21	rogid:cbcOBnZB/W/Y7eE/IxM2HfZHpK49606	rogid:2dMXDgdLO6QABzj1zgHf0AlJ7dA9606	rigid:jTpjq5aiw8wKlLyg+wKSBFv3Ogc	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P02679	uniprotkb:Q99757-PRO_0000034150	intact:EBI-1034422|uniprotkb:P04469|uniprotkb:P04470|uniprotkb:Q96A14|uniprotkb:Q96KJ3|uniprotkb:A8K057|uniprotkb:Q53Y18|uniprotkb:Q9UC62|uniprotkb:Q9UC63|uniprotkb:Q9UCF3|ensembl:ENSP00000336829	intact:EBI-26565164	psi-mi:fibg_human(display_long)|uniprotkb:FGG(gene name)|psi-mi:FGG(display_short)|uniprotkb:PRO2061(orf name)	psi-mi:q99757-pro_0000034150(display_long)|uniprotkb:Thioredoxin-2(gene name synonym)|uniprotkb:TXN2(gene name)|psi-mi:TXN2(display_short)|uniprotkb:TRX2(gene name synonym)	psi-mi:"MI:0018"(two hybrid)	Chasapis et al. (2019)	pubmed:31018154|imex:IM-28571	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26500867|imex:IM-28571-7	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_000500.2|refseq:NP_068656.2|ensembl:ENSG00000171557(gene)|ensembl:ENST00000336098(transcript)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005201"(extracellular matrix structural constituent)|go:"GO:0005576"(extracellular region)|go:"GO:0005577"(fibrinogen complex)|go:"GO:0005615"(extracellular space)|go:"GO:0005788"(endoplasmic reticulum lumen)|go:"GO:0005886"(plasma membrane)|go:"GO:0007160"(cell-matrix adhesion)|go:"GO:0071347"(cellular response to interleukin-1)|go:"GO:0009306"(protein secretion)|go:"GO:0071354"(cellular response to interleukin-6)|go:"GO:0009897"(external side of plasma membrane)|go:"GO:0009986"(cell surface)|go:"GO:0031091"(platelet alpha granule)|go:"GO:0031093"(platelet alpha granule lumen)|go:"GO:0031639"(plasminogen activation)|go:"GO:0034116"(positive regulation of heterotypic cell-cell adhesion)|go:"GO:0034622"|go:"GO:0036345"(platelet maturation)|go:"GO:0042730"(fibrinolysis)|go:"GO:0042802"(identical protein binding)|go:"GO:0045907"(positive regulation of vasoconstriction)|go:"GO:0045921"(positive regulation of exocytosis)|go:"GO:0046872"(metal ion binding)|go:"GO:0050714"(positive regulation of protein secretion)|go:"GO:0050839"(cell adhesion molecule binding)|go:"GO:0051258"(protein polymerization)|go:"GO:0051592"(response to calcium ion)|go:"GO:0062023"(collagen-containing extracellular matrix)|go:"GO:0072378"(blood coagulation, fibrin clot formation)|go:"GO:0072562"(blood microparticle)|go:"GO:0090277"(positive regulation of peptide hormone secretion)|go:"GO:0090331"(negative regulation of platelet aggregation)|go:"GO:0070062"(extracellular exosome)|go:"GO:1900026"(positive regulation of substrate adhesion-dependent cell spreading)|go:"GO:1902042"(negative regulation of extrinsic apoptotic signaling pathway via death domain receptors)|go:"GO:2000352"(negative regulation of endothelial cell apoptotic process)|interpro:IPR002181(Fibrinogen, alpha/beta/gamma chain, C-terminal globular)|interpro:IPR012290(Fibrinogen, alpha/beta/gamma chain, coiled coil)|interpro:IPR014716(Fibrinogen, alpha/beta/gamma chain, C-terminal globular, subdomain 1)|interpro:IPR020837|interpro:IPR036056|go:"GO:0070374"(positive regulation of ERK1 and ERK2 cascade)|interpro:IPR037581|mint:P02679|rcsb pdb:1DUG|rcsb pdb:1FIB|rcsb pdb:1FIC|rcsb pdb:1FID|rcsb pdb:1FZA|go:"GO:0070527"(platelet aggregation)|rcsb pdb:1FZB|rcsb pdb:1FZC|rcsb pdb:1FZE|rcsb pdb:1FZF|rcsb pdb:1FZG|rcsb pdb:1LT9|rcsb pdb:1LTJ|rcsb pdb:1N86|rcsb pdb:1N8E|rcsb pdb:1RE3|rcsb pdb:1RE4|rcsb pdb:1RF0|rcsb pdb:1RF1|rcsb pdb:2A45|rcsb pdb:2FFD|rcsb pdb:2FIB|rcsb pdb:2H43|rcsb pdb:2HLO|rcsb pdb:2HOD|rcsb pdb:2HPC|rcsb pdb:2HWL|rcsb pdb:2OYH|rcsb pdb:2OYI|rcsb pdb:2VDO|rcsb pdb:2VDP|rcsb pdb:2VDQ|rcsb pdb:2VDR|rcsb pdb:2VR3|rcsb pdb:2XNX|rcsb pdb:2XNY|rcsb pdb:2Y7L|rcsb pdb:2Z4E|rcsb pdb:3BVH|rcsb pdb:3E1I|rcsb pdb:2Q9I|rcsb pdb:3FIB|rcsb pdb:3GHG|rcsb pdb:3H32|rcsb pdb:3HUS|rcsb pdb:4B60|reactome:R-HSA-114608|reactome:R-HSA-1236974|reactome:R-HSA-140875|reactome:R-HSA-166058|reactome:R-HSA-216083|reactome:R-HSA-354192|reactome:R-HSA-354194|reactome:R-HSA-372708|reactome:R-HSA-381426|reactome:R-HSA-5602498|reactome:R-HSA-5603041|reactome:R-HSA-5674135|reactome:R-HSA-5686938|reactome:R-HSA-6802946|reactome:R-HSA-6802948|reactome:R-HSA-6802952|reactome:R-HSA-6802955|reactome:R-HSA-8957275|reactome:R-HSA-9649948|reactome:R-HSA-9656223|dip:DIP-29644N	intact:EBI-2932492(chain-parent)	-	-	chain-seq-start:60|chain-seq-end:166	figure legend:ST2.2|dataset:Rare diseases - Interactions investigated in the context of Rare genetic disease|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	-	2020/12/04	2020/12/21	rogid:QKWesyU4/fduceFtu5zq31oGhYI9606	rogid:2dMXDgdLO6QABzj1zgHf0AlJ7dA9606	rigid:X7qWNv0XgBjSqQK+U7ORGIZ9fvY	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P63261	uniprotkb:Q99757-PRO_0000034150	intact:EBI-351292|uniprotkb:P02571|uniprotkb:P14104|uniprotkb:P99022|uniprotkb:Q5U032|uniprotkb:Q96E67|uniprotkb:A8K7C2|ensembl:ENSP00000505060|ensembl:ENSP00000505193|ensembl:ENSP00000505235|ensembl:ENSP00000506126|ensembl:ENSP00000506201|ensembl:ENSP00000506253|ensembl:ENSP00000458162|ensembl:ENSP00000458435|ensembl:ENSP00000459119|ensembl:ENSP00000459124|ensembl:ENSP00000460464|ensembl:ENSP00000460660|ensembl:ENSP00000461672|ensembl:ENSP00000466346|ensembl:ENSP00000477968	intact:EBI-26565164	psi-mi:actg_human(display_long)|uniprotkb:ACTG1(gene name)|psi-mi:ACTG1(display_short)|uniprotkb:ACTG(gene name synonym)|uniprotkb:Gamma-actin(gene name synonym)	psi-mi:q99757-pro_0000034150(display_long)|uniprotkb:Thioredoxin-2(gene name synonym)|uniprotkb:TXN2(gene name)|psi-mi:TXN2(display_short)|uniprotkb:TRX2(gene name synonym)	psi-mi:"MI:0018"(two hybrid)	Chasapis et al. (2019)	pubmed:31018154|imex:IM-28571	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26500873|imex:IM-28571-9	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001186883.1|refseq:NP_001605.1|ensembl:ENST00000570382(transcript)|ensembl:ENSG00000184009(gene)|ensembl:ENST00000571721(transcript)|ensembl:ENST00000573283(transcript)|ensembl:ENST00000575087(transcript)|ensembl:ENST00000575659(transcript)|ensembl:ENST00000575842(transcript)|ensembl:ENST00000575994(transcript)|ensembl:ENST00000576544(transcript)|ensembl:ENST00000615544(transcript)|ensembl:ENST00000679480(transcript)|ensembl:ENST00000679778(transcript)|ensembl:ENST00000680227(transcript)|ensembl:ENST00000680727(transcript)|ensembl:ENST00000681052(transcript)|ensembl:ENST00000681842(transcript)|go:"GO:0001525"(angiogenesis)|go:"GO:0001738"(morphogenesis of a polarized epithelium)|go:"GO:0001895"(retina homeostasis)|go:"GO:0005200"(structural constituent of cytoskeleton)|go:"GO:0005522"(profilin binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005884"(actin filament)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005925"(focal adhesion)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0016020"(membrane)|go:"GO:0030016"(myofibril)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0031941"(filamentous actin)|go:"GO:0035633"(maintenance of blood-brain barrier)|go:"GO:0042802"(identical protein binding)|go:"GO:0043296"(apical junction complex)|go:"GO:0044305"(calyx of Held)|go:"GO:0045214"(sarcomere organization)|go:"GO:0045335"(phagocytic vesicle)|go:"GO:0048488"(synaptic vesicle endocytosis)|go:"GO:0051492"(regulation of stress fiber assembly)|go:"GO:0051893"(regulation of focal adhesion assembly)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070527"(platelet aggregation)|go:"GO:0071346"(cellular response to interferon-gamma)|go:"GO:0072562"(blood microparticle)|go:"GO:0090303"(positive regulation of wound healing)|go:"GO:0097433"(dense body)|go:"GO:0098685"(Schaffer collateral - CA1 synapse)|go:"GO:0098973"(structural constituent of postsynaptic actin cytoskeleton)|go:"GO:0120192"(tight junction assembly)|go:"GO:0120220"(basal body patch)|go:"GO:0150111"(regulation of transepithelial transport)|go:"GO:1902396"(protein localization to bicellular tight junction)|interpro:IPR004000(Actin/actin-like)|interpro:IPR004001(Actin, conserved site)|interpro:IPR020902|interpro:IPR043129|mint:P63261|rcsb pdb:5JLH|rcsb pdb:6CXI|rcsb pdb:6CXJ|rcsb pdb:6G2T|rcsb pdb:6V62|rcsb pdb:6V63|rcsb pdb:6WK1|rcsb pdb:6WK2|reactome:R-HSA-1445148|reactome:R-HSA-190873|reactome:R-HSA-196025|reactome:R-HSA-2029482|reactome:R-HSA-3928662|reactome:R-HSA-3928665|reactome:R-HSA-418990|reactome:R-HSA-437239|reactome:R-HSA-4420097|reactome:R-HSA-445095|reactome:R-HSA-446353|reactome:R-HSA-5626467|reactome:R-HSA-5663213|reactome:R-HSA-5663220|reactome:R-HSA-5674135|reactome:R-HSA-6802946|reactome:R-HSA-6802948|reactome:R-HSA-6802952|reactome:R-HSA-6802955|reactome:R-HSA-8856828|reactome:R-HSA-9013418|reactome:R-HSA-9649948|reactome:R-HSA-9656223|reactome:R-HSA-9662360|reactome:R-HSA-9662361|reactome:R-HSA-9664422	intact:EBI-2932492(chain-parent)	-	-	chain-seq-start:60|chain-seq-end:166	figure legend:ST2.2|dataset:Rare diseases - Interactions investigated in the context of Rare genetic disease|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	-	2020/12/04	2020/12/21	rogid:B2OOsE06lTfo90H3g8tlmUJQ7cY9606	rogid:2dMXDgdLO6QABzj1zgHf0AlJ7dA9606	rigid:BX6pHjgp4BSs0pXNJ4Dm9tHisz0	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q7Z406	uniprotkb:Q99757-PRO_0000034150	intact:EBI-355595|uniprotkb:Q5CZ75|uniprotkb:Q6XYE4|uniprotkb:Q76B62|uniprotkb:Q8WV23|uniprotkb:Q96I22|uniprotkb:Q9BT27|uniprotkb:Q9BW35|uniprotkb:Q9H882|uniprotkb:B0I1S2|ensembl:ENSP00000366169|ensembl:ENSP00000472819|uniprotkb:C3TTN4	intact:EBI-26565164	psi-mi:myh14_human(display_long)|uniprotkb:MYH14(gene name)|psi-mi:MYH14(display_short)|uniprotkb:KIAA2034(gene name synonym)|uniprotkb:FP17425(orf name)|uniprotkb:Myosin heavy chain 14(gene name synonym)|uniprotkb:Myosin heavy chain, non-muscle IIc(gene name synonym)|uniprotkb:Non-muscle myosin heavy chain IIc(gene name synonym)	psi-mi:q99757-pro_0000034150(display_long)|uniprotkb:Thioredoxin-2(gene name synonym)|uniprotkb:TXN2(gene name)|psi-mi:TXN2(display_short)|uniprotkb:TRX2(gene name synonym)	psi-mi:"MI:0018"(two hybrid)	Chasapis et al. (2019)	pubmed:31018154|imex:IM-28571	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26500879|imex:IM-28571-47	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001070654.1|refseq:NP_001139281.1|refseq:NP_079005.3|refseq:XP_011525625.1|ensembl:ENSG00000105357(gene)|ensembl:ENST00000376970(transcript)|ensembl:ENST00000596571(transcript)|go:"GO:0000146"(microfilament motor activity)|go:"GO:0001725"(stress fiber)|go:"GO:0003009"(skeletal muscle contraction)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005829"(cytosol)|go:"GO:0005903"(brush border)|go:"GO:0007519"(skeletal muscle tissue development)|go:"GO:0007605"(sensory perception of sound)|go:"GO:0008360"(regulation of cell shape)|go:"GO:0016020"(membrane)|go:"GO:0016460"(myosin II complex)|go:"GO:0016887"(ATP hydrolysis activity)|go:"GO:0019228"(neuronal action potential)|go:"GO:0030048"(actin filament-based movement)|go:"GO:0030426"(growth cone)|go:"GO:0031032"(actomyosin structure organization)|go:"GO:0042641"(actomyosin)|go:"GO:0051015"(actin filament binding)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070584"(mitochondrion morphogenesis)|go:"GO:0071625"(vocalization behavior)|go:"GO:0097513"(myosin II filament)|interpro:IPR000048(IQ calmodulin-binding region)|interpro:IPR001609(Myosin head, motor region)|interpro:IPR004009(Myosin, N-terminal, SH3-like)|interpro:IPR008989(Myosin S1 fragment, N-terminal)|interpro:IPR027417|interpro:IPR036961|mint:Q7Z406|rcsb pdb:5I4E|rcsb pdb:5JLH|reactome:R-HSA-3928663|reactome:R-HSA-416572|reactome:R-HSA-5625740|reactome:R-HSA-5625900|reactome:R-HSA-5627117|reactome:R-HSA-5627123|interpro:IPR002928(Myosin tail)|refseq:XP_006723449.1|dip:DIP-33170N	intact:EBI-2932492(chain-parent)	-	-	chain-seq-start:60|chain-seq-end:166	figure legend:ST2.2|dataset:Rare diseases - Interactions investigated in the context of Rare genetic disease|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	-	2020/12/04	2020/12/21	rogid:6aY3HPa5DIY5UadiOTTh/uSPi/M9606	rogid:2dMXDgdLO6QABzj1zgHf0AlJ7dA9606	rigid:n6SmpL078WOFbmSgJ/HIxNwLGxQ	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P29966	uniprotkb:Q99757-PRO_0000034150	intact:EBI-1047781|uniprotkb:E1P560|uniprotkb:Q2LA83|uniprotkb:Q5TDB7|ensembl:ENSP00000478061	intact:EBI-26565164	psi-mi:marcs_human(display_long)|uniprotkb:Protein kinase C substrate, 80 kDa protein, light chain(gene name synonym)|uniprotkb:MARCKS(gene name)|psi-mi:MARCKS(display_short)|uniprotkb:MACS(gene name synonym)|uniprotkb:PRKCSL(gene name synonym)	psi-mi:q99757-pro_0000034150(display_long)|uniprotkb:Thioredoxin-2(gene name synonym)|uniprotkb:TXN2(gene name)|psi-mi:TXN2(display_short)|uniprotkb:TRX2(gene name synonym)	psi-mi:"MI:0018"(two hybrid)	Chasapis et al. (2019)	pubmed:31018154|imex:IM-28571	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26500885|imex:IM-28571-33	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_002347.5|ensembl:ENSG00000277443(gene)|ensembl:ENST00000612661(transcript)|go:"GO:0005080"(protein kinase C binding)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005886"(plasma membrane)|go:"GO:0005925"(focal adhesion)|go:"GO:0005938"(cell cortex)|go:"GO:0007015"(actin filament organization)|go:"GO:0007417"(central nervous system development)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0032432"(actin filament bundle)|go:"GO:0042585"(germinal vesicle)|go:"GO:0042802"(identical protein binding)|go:"GO:0051015"(actin filament binding)|go:"GO:0051017"(actin filament bundle assembly)|go:"GO:0051764"(actin crosslink formation)|go:"GO:0070062"(extracellular exosome)|interpro:IPR002101(Myristoylated alanine-rich C-kinase substrate MARCKS)|mint:P29966|reactome:R-HSA-399997	intact:EBI-2932492(chain-parent)	-	-	chain-seq-start:60|chain-seq-end:166	figure legend:ST2.2|dataset:Rare diseases - Interactions investigated in the context of Rare genetic disease|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	-	2020/12/04	2020/12/21	rogid:28v6sOqwULr0AvfJr7yAal9Yh1g9606	rogid:2dMXDgdLO6QABzj1zgHf0AlJ7dA9606	rigid:EE8NvUz1j5cFo8JXcKY/kBmJ8rQ	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q04206	uniprotkb:Q99757-PRO_0000034150	intact:EBI-73886|ensembl:ENSP00000384273|uniprotkb:Q6GTV1|uniprotkb:Q6SLK1	intact:EBI-26565164	psi-mi:tf65_human(display_long)|uniprotkb:Nuclear factor NF-kappa-B p65 subunit(gene name synonym)|uniprotkb:RELA(gene name)|psi-mi:RELA(display_short)|uniprotkb:NFKB3(gene name synonym)|uniprotkb:Nuclear factor of kappa light polypeptide gene enhancer in B-cells 3(gene name synonym)	psi-mi:q99757-pro_0000034150(display_long)|uniprotkb:Thioredoxin-2(gene name synonym)|uniprotkb:TXN2(gene name)|psi-mi:TXN2(display_short)|uniprotkb:TRX2(gene name synonym)	psi-mi:"MI:0018"(two hybrid)	Chasapis et al. (2019)	pubmed:31018154|imex:IM-28571	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26500892|imex:IM-28571-11	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000173039(gene)|ensembl:ENST00000406246(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000979"(RNA polymerase II core promoter sequence-specific DNA binding)|refseq:NP_001138610.1|refseq:NP_068810.3|refseq:NP_001230913.1|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0070301"(cellular response to hydrogen peroxide)|dip:DIP-24238N|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001889"(liver development)|go:"GO:0001942"(hair follicle development)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006117"(acetaldehyde metabolic process)|go:"GO:0006325"(chromatin organization)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006954"(inflammatory response)|go:"GO:0006968"(cellular defense response)|go:"GO:0007249"(I-kappaB kinase/NF-kappaB signaling)|go:"GO:0007568"(aging)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0009887"(animal organ morphogenesis)|go:"GO:0010033"(response to organic substance)|go:"GO:0010224"(response to UV-B)|go:"GO:0014040"(positive regulation of Schwann cell differentiation)|go:"GO:0019221"(cytokine-mediated signaling pathway)|go:"GO:0019899"(enzyme binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0031490"(chromatin DNA binding)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032495"(response to muramyl dipeptide)|go:"GO:0032570"(response to progesterone)|go:"GO:0032735"(positive regulation of interleukin-12 production)|go:"GO:0032757"(positive regulation of interleukin-8 production)|go:"GO:0032868"(response to insulin)|go:"GO:0033209"(tumor necrosis factor-mediated signaling pathway)|go:"GO:0033234"(negative regulation of protein sumoylation)|go:"GO:0033590"(response to cobalamin)|go:"GO:0034097"(response to cytokine)|go:"GO:0035525"(NF-kappaB p50/p65 complex)|go:"GO:0035729"(cellular response to hepatocyte growth factor stimulus)|go:"GO:0035924"(cellular response to vascular endothelial growth factor stimulus)|go:"GO:0035994"(response to muscle stretch)|go:"GO:0038061"(NIK/NF-kappaB signaling)|go:"GO:0042177"(negative regulation of protein catabolic process)|go:"GO:0042277"(peptide binding)|go:"GO:0042301"(phosphate ion binding)|go:"GO:0042493"|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0042805"(actinin binding)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043200"(response to amino acid)|go:"GO:0043278"(response to morphine)|go:"GO:0043620"(regulation of DNA-templated transcription in response to stress)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045087"(innate immune response)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046627"(negative regulation of insulin receptor signaling pathway)|go:"GO:0047485"(protein N-terminus binding)|go:"GO:0050727"(regulation of inflammatory response)|go:"GO:0050862"(positive regulation of T cell receptor signaling pathway)|go:"GO:0051059"(NF-kappaB binding)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|go:"GO:0051591"(response to cAMP)|go:"GO:0001223"(transcription coactivator binding)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0051607"(defense response to virus)|go:"GO:0070431"(nucleotide-binding oligomerization domain containing 2 signaling pathway)|go:"GO:0070498"(interleukin-1-mediated signaling pathway)|go:"GO:0070555"(response to interleukin-1)|go:"GO:0071222"(cellular response to lipopolysaccharide)|go:"GO:0071223"(cellular response to lipoteichoic acid)|go:"GO:0071224"(cellular response to peptidoglycan)|go:"GO:0071316"(cellular response to nicotine)|go:"GO:0071347"(cellular response to interleukin-1)|go:"GO:0071354"(cellular response to interleukin-6)|go:"GO:0071356"(cellular response to tumor necrosis factor)|go:"GO:0071532"(ankyrin repeat binding)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099527"(postsynapse to nucleus signaling pathway)|go:"GO:0140296"(general transcription initiation factor binding)|go:"GO:0140297"(DNA-binding transcription factor binding)|go:"GO:1901222"(regulation of NIK/NF-kappaB signaling)|go:"GO:1901223"(negative regulation of NIK/NF-kappaB signaling)|go:"GO:1901224"(positive regulation of NIK/NF-kappaB signaling)|go:"GO:1901522"(positive regulation of transcription from RNA polymerase II promoter involved in cellular response to chemical stimulus)|go:"GO:1902004"(positive regulation of amyloid-beta formation)|go:"GO:1902894"(negative regulation of miRNA transcription)|go:"GO:1902895"(positive regulation of miRNA transcription)|go:"GO:1904385"(cellular response to angiotensin)|go:"GO:1904996"(positive regulation of leukocyte adhesion to vascular endothelial cell)|go:"GO:2000630"(positive regulation of miRNA metabolic process)|go:"GO:2001237"(negative regulation of extrinsic apoptotic signaling pathway)|interpro:IPR000451(NF-kappa-B/Rel/dorsal)|interpro:IPR002909(Cell surface receptor IPT/TIG)|interpro:IPR008967(p53-like transcription factor, DNA-binding)|interpro:IPR011539(Rel homology)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR014756(Immunoglobulin E-set)|interpro:IPR030492|interpro:IPR030495|interpro:IPR032397|interpro:IPR033926|interpro:IPR037059|mint:Q04206|rcsb pdb:1NFI|rcsb pdb:2LSP|rcsb pdb:2O61|rcsb pdb:3GUT|rcsb pdb:3QXY|rcsb pdb:3RC0|rcsb pdb:4KV1|rcsb pdb:4KV4|rcsb pdb:5U4K|rcsb pdb:5URN|rcsb pdb:6NV2|rcsb pdb:6QHL|rcsb pdb:6QHM|rcsb pdb:6YOW|rcsb pdb:6YOX|rcsb pdb:6YOY|rcsb pdb:6YP2|rcsb pdb:6YP3|rcsb pdb:6YP8|rcsb pdb:6YPL|rcsb pdb:6YPY|rcsb pdb:6YQ2|rcsb pdb:7BI3|rcsb pdb:7BIQ|rcsb pdb:7BIY|rcsb pdb:7BJF|rcsb pdb:7BJL|rcsb pdb:7BJW|rcsb pdb:7BKH|rcsb pdb:7NJ9|rcsb pdb:7NJB|rcsb pdb:7NK3|rcsb pdb:7NK5|rcsb pdb:7NLA|rcsb pdb:7NLE|rcsb pdb:7NM1|rcsb pdb:7NM3|rcsb pdb:7NM9|rcsb pdb:7NQP|rcsb pdb:7NR7|rcsb pdb:7NSV|rcsb pdb:7NV4|rcsb pdb:7NVI|rcsb pdb:7NWS|rcsb pdb:7NXS|rcsb pdb:7NXT|rcsb pdb:7NXW|rcsb pdb:7NXY|rcsb pdb:7NY4|rcsb pdb:7NYE|rcsb pdb:7NYF|rcsb pdb:7NYG|rcsb pdb:7NZ6|rcsb pdb:7NZG|rcsb pdb:7NZK|rcsb pdb:7NZV|rcsb pdb:7O34|rcsb pdb:7O3A|rcsb pdb:7O3F|rcsb pdb:7O3P|rcsb pdb:7O3Q|rcsb pdb:7O3R|rcsb pdb:7O3S|rcsb pdb:7O57|rcsb pdb:7O59|rcsb pdb:7O5A|rcsb pdb:7O5C|rcsb pdb:7O5D|rcsb pdb:7O5F|rcsb pdb:7O5G|rcsb pdb:7O5O|rcsb pdb:7O5P|rcsb pdb:7O5S|rcsb pdb:7O5U|rcsb pdb:7O5X|rcsb pdb:7O6F|rcsb pdb:7O6G|rcsb pdb:7O6I|rcsb pdb:7O6J|rcsb pdb:7O6K|rcsb pdb:7O6M|rcsb pdb:7O6O|reactome:R-HSA-1169091|reactome:R-HSA-1810476|reactome:R-HSA-193692|reactome:R-HSA-202424|reactome:R-HSA-209560|reactome:R-HSA-2559582|reactome:R-HSA-2871837|reactome:R-HSA-3134963|reactome:R-HSA-3214841|reactome:R-HSA-381340|reactome:R-HSA-445989|reactome:R-HSA-448706|reactome:R-HSA-4755510|reactome:R-HSA-5603029|reactome:R-HSA-5607761|reactome:R-HSA-5607764|reactome:R-HSA-5621575|reactome:R-HSA-5660668|reactome:R-HSA-844456|reactome:R-HSA-8853884|reactome:R-HSA-9020702|reactome:R-HSA-933542|reactome:R-HSA-9660826	intact:EBI-2932492(chain-parent)	-	-	chain-seq-start:60|chain-seq-end:166	figure legend:ST2.2|dataset:Rare diseases - Interactions investigated in the context of Rare genetic disease|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	-	2020/12/04	2020/12/21	rogid:w/ClZ7PzdLH1LLxTGrk22KUz8V49606	rogid:2dMXDgdLO6QABzj1zgHf0AlJ7dA9606	rigid:ltkKRR8TGUlZKnLZK0duSWYIW2U	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q14442	uniprotkb:Q99757-PRO_0000034150	intact:EBI-2803676|uniprotkb:B2RAA4|ensembl:ENSP00000216452	intact:EBI-26565164	psi-mi:pigh_human(display_long)|uniprotkb:Phosphatidylinositol-glycan biosynthesis class H protein(gene name synonym)|uniprotkb:PIGH(gene name)|psi-mi:PIGH(display_short)	psi-mi:q99757-pro_0000034150(display_long)|uniprotkb:Thioredoxin-2(gene name synonym)|uniprotkb:TXN2(gene name)|psi-mi:TXN2(display_short)|uniprotkb:TRX2(gene name synonym)	psi-mi:"MI:0018"(two hybrid)	Chasapis et al. (2019)	pubmed:31018154|imex:IM-28571	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26500898|imex:IM-28571-13	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000100564(gene)|ensembl:ENST00000216452(transcript)|go:"GO:0000506"("glycosylphosphatidylinositol-N-acetylglucosaminyltransferase (GPI-GnT) complex")|go:"GO:0003824"(catalytic activity)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006464"(cellular protein modification process)|go:"GO:0017176"(phosphatidylinositol N-acetylglucosaminyltransferase activity)|interpro:IPR019328|interpro:IPR044215|mint:Q14442|reactome:R-HSA-162710|go:"GO:0006506"(GPI anchor biosynthetic process)|refseq:NP_004560.1	intact:EBI-2932492(chain-parent)	-	-	chain-seq-start:60|chain-seq-end:166	figure legend:ST2.2|dataset:Rare diseases - Interactions investigated in the context of Rare genetic disease|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	-	2020/12/04	2020/12/21	rogid:wCS89Qt+gANFwAjAEFGvsQhXsqU9606	rogid:2dMXDgdLO6QABzj1zgHf0AlJ7dA9606	rigid:YaXEMSPOp9lajG3Zv9vKItAqeEE	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P00747	uniprotkb:Q99757-PRO_0000034150	intact:EBI-999394|uniprotkb:Q15146|uniprotkb:Q5TEH4|uniprotkb:Q6PA00|ensembl:ENSP00000308938	intact:EBI-26565164	psi-mi:plmn_human(display_long)|uniprotkb:PLG(gene name)|psi-mi:PLG(display_short)	psi-mi:q99757-pro_0000034150(display_long)|uniprotkb:Thioredoxin-2(gene name synonym)|uniprotkb:TXN2(gene name)|psi-mi:TXN2(display_short)|uniprotkb:TRX2(gene name synonym)	psi-mi:"MI:0018"(two hybrid)	Chasapis et al. (2019)	pubmed:31018154|imex:IM-28571	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26500904|imex:IM-28571-49	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_000292.1|ensembl:ENSG00000122194(gene)|ensembl:ENST00000308192(transcript)|go:"GO:0004175"(endopeptidase activity)|go:"GO:0004252"(serine-type endopeptidase activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0006508"(proteolysis)|go:"GO:0007596"(blood coagulation)|go:"GO:0008236"(serine-type peptidase activity)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0009986"(cell surface)|go:"GO:0010812"(negative regulation of cell-substrate adhesion)|go:"GO:0019899"(enzyme binding)|go:"GO:0019900"(kinase binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0022617"(extracellular matrix disassembly)|go:"GO:0031093"(platelet alpha granule lumen)|go:"GO:0031232"(extrinsic component of external side of plasma membrane)|go:"GO:0034185"(apolipoprotein binding)|go:"GO:0042730"(fibrinolysis)|go:"GO:0043536"(positive regulation of blood vessel endothelial cell migration)|go:"GO:0048771"(tissue remodeling)|go:"GO:0051087"(chaperone binding)|go:"GO:0051702"(biological process involved in interaction with symbiont)|go:"GO:0051918"(negative regulation of fibrinolysis)|go:"GO:0051919"(positive regulation of fibrinolysis)|go:"GO:0062023"(collagen-containing extracellular matrix)|go:"GO:0070062"(extracellular exosome)|go:"GO:0072562"(blood microparticle)|go:"GO:1990405"(protein antigen binding)|go:"GO:2000048"(negative regulation of cell-cell adhesion mediated by cadherin)|interpro:IPR000001(Kringle)|interpro:IPR001254(Peptidase S1 and S6, chymotrypsin/Hap)|interpro:IPR001314(Peptidase S1A, chymotrypsin)|interpro:IPR003609(Apple-like)|interpro:IPR009003(Peptidase, trypsin-like serine and cysteine)|go:"GO:0005102"(signaling receptor binding)|interpro:IPR013806(Kringle-like fold)|interpro:IPR018056|interpro:IPR018114|interpro:IPR023317|interpro:IPR033116|interpro:IPR038178|interpro:IPR043504|mint:P00747|rcsb pdb:1B2I|rcsb pdb:1BML|rcsb pdb:1BUI|rcsb pdb:1CEA|rcsb pdb:1CEB|rcsb pdb:1DDJ|rcsb pdb:1HPJ|rcsb pdb:1HPK|rcsb pdb:1I5K|rcsb pdb:1KI0|rcsb pdb:1KRN|rcsb pdb:1L4D|rcsb pdb:1L4Z|rcsb pdb:1PK4|rcsb pdb:1PKR|rcsb pdb:1PMK|rcsb pdb:1QRZ|rcsb pdb:1RJX|rcsb pdb:2DOH|rcsb pdb:2DOI|rcsb pdb:2KNF|rcsb pdb:2L0S|rcsb pdb:2PK4|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|rcsb pdb:3UIR|rcsb pdb:4A5T|rcsb pdb:4CIK|rcsb pdb:4DCB|rcsb pdb:4DUR|rcsb pdb:4DUU|rcsb pdb:5HPG|rcsb pdb:5UGD|rcsb pdb:5UGG|rcsb pdb:6D3X|rcsb pdb:6D3Y|rcsb pdb:6D3Z|rcsb pdb:6D40|rcsb pdb:6OG4|rcsb pdb:6OQJ|rcsb pdb:6OQK|rcsb pdb:6Q1U|rcsb pdb:6UZ4|rcsb pdb:6UZ5|reactome:R-HSA-114608|reactome:R-HSA-1474228|reactome:R-HSA-1592389|reactome:R-HSA-186797|reactome:R-HSA-381426|reactome:R-HSA-75205	intact:EBI-2932492(chain-parent)	-	-	chain-seq-start:60|chain-seq-end:166	figure legend:ST2.2|dataset:Rare diseases - Interactions investigated in the context of Rare genetic disease|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	-	2020/12/04	2020/12/21	rogid:f9Y+uCcA1jrDN1AD/clsKtkZWEQ9606	rogid:2dMXDgdLO6QABzj1zgHf0AlJ7dA9606	rigid:FCpGlNs+h9TBhFBFHAo1W1WfFm0	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P07237	uniprotkb:Q99757-PRO_0000034150	intact:EBI-395883|uniprotkb:P30037|uniprotkb:P32079|uniprotkb:Q15205|uniprotkb:Q6LDE5|uniprotkb:B2RDQ2|ensembl:ENSP00000327801	intact:EBI-26565164	psi-mi:pdia1_human(display_long)|uniprotkb:P4HB(gene name)|psi-mi:P4HB(display_short)|uniprotkb:PDI(gene name synonym)|uniprotkb:PDIA1(gene name synonym)|uniprotkb:PO4DB(gene name synonym)|uniprotkb:Prolyl 4-hydroxylase subunit beta(gene name synonym)|uniprotkb:Cellular thyroid hormone-binding protein(gene name synonym)|uniprotkb:p55(gene name synonym)|uniprotkb:ERBA2L(gene name synonym)	psi-mi:q99757-pro_0000034150(display_long)|uniprotkb:Thioredoxin-2(gene name synonym)|uniprotkb:TXN2(gene name)|psi-mi:TXN2(display_short)|uniprotkb:TRX2(gene name synonym)	psi-mi:"MI:0018"(two hybrid)	Chasapis et al. (2019)	pubmed:31018154|imex:IM-28571	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26500910|imex:IM-28571-51	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_000909.2|ensembl:ENSG00000185624(gene)|ensembl:ENST00000331483(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0003756"(protein disulfide isomerase activity)|go:"GO:0003779"(actin binding)|go:"GO:0004656"(procollagen-proline 4-dioxygenase activity)|go:"GO:0005178"(integrin binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005788"(endoplasmic reticulum lumen)|go:"GO:0005793"(endoplasmic reticulum-Golgi intermediate compartment)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005925"(focal adhesion)|go:"GO:0006457"(protein folding)|go:"GO:0009897"(external side of plasma membrane)|go:"GO:0015035"(protein-disulfide reductase activity)|go:"GO:0016222"(procollagen-proline 4-dioxygenase complex)|go:"GO:0016972"(thiol oxidase activity)|go:"GO:0018401"(peptidyl-proline hydroxylation to 4-hydroxy-L-proline)|go:"GO:0019899"(enzyme binding)|go:"GO:0030027"(lamellipodium)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034663"(endoplasmic reticulum chaperone complex)|go:"GO:0034975"(protein folding in endoplasmic reticulum)|go:"GO:0034976"(response to endoplasmic reticulum stress)|go:"GO:0035722"(interleukin-12-mediated signaling pathway)|go:"GO:0038155"(interleukin-23-mediated signaling pathway)|go:"GO:0042470"(melanosome)|go:"GO:0045785"(positive regulation of cell adhesion)|go:"GO:0046598"(positive regulation of viral entry into host cell)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071456"(cellular response to hypoxia)|go:"GO:0098761"(cellular response to interleukin-7)|go:"GO:1900026"(positive regulation of substrate adhesion-dependent cell spreading)|go:"GO:1902175"(regulation of oxidative stress-induced intrinsic apoptotic signaling pathway)|interpro:IPR005788(Disulphide isomerase)|interpro:IPR005792(Protein disulphide isomerase)|interpro:IPR013766(Thioredoxin domain)|interpro:IPR017937|interpro:IPR036249|mint:P07237|rcsb pdb:1BJX|rcsb pdb:1MEK|rcsb pdb:1X5C|rcsb pdb:2BJX|rcsb pdb:2K18|rcsb pdb:3BJ5|rcsb pdb:3UEM|rcsb pdb:4EKZ|rcsb pdb:4EL1|rcsb pdb:4JU5|rcsb pdb:6I7S|reactome:R-HSA-1650814|reactome:R-HSA-3299685|reactome:R-HSA-381426|reactome:R-HSA-5358346|reactome:R-HSA-8866423|reactome:R-HSA-8957275|reactome:R-HSA-8963888|reactome:R-HSA-9020591|reactome:R-HSA-9020933|dip:DIP-32979N	intact:EBI-2932492(chain-parent)	-	-	chain-seq-start:60|chain-seq-end:166	figure legend:ST2.2|dataset:Rare diseases - Interactions investigated in the context of Rare genetic disease|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	-	2020/12/04	2020/12/21	rogid:rh0B38TSfTX+lvU5OyBwEbVndFA9606	rogid:2dMXDgdLO6QABzj1zgHf0AlJ7dA9606	rigid:A4fRd4HKHJymsy3rDMI9u1XtY+w	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q53ET4	uniprotkb:Q99757-PRO_0000034150	intact:EBI-26500828	intact:EBI-26565164	psi-mi:q53et4_human(display_long)	psi-mi:q99757-pro_0000034150(display_long)|uniprotkb:Thioredoxin-2(gene name synonym)|uniprotkb:TXN2(gene name)|psi-mi:TXN2(display_short)|uniprotkb:TRX2(gene name synonym)	psi-mi:"MI:0018"(two hybrid)	Chasapis et al. (2019)	pubmed:31018154|imex:IM-28571	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26500916|imex:IM-28571-53	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	go:"GO:0004372"(glycine hydroxymethyltransferase activity)|go:"GO:0008168"(methyltransferase activity)|go:"GO:0019264"(glycine biosynthetic process from serine)|go:"GO:0030170"(pyridoxal phosphate binding)|go:"GO:0032259"(methylation)|go:"GO:0035999"(tetrahydrofolate interconversion)|mint:Q53ET4|interpro:IPR015424(Pyridoxal phosphate-dependent transferase, major region)|interpro:IPR015422(Pyridoxal phosphate-dependent transferase, major region, subdomain 2)|interpro:IPR015421(Pyridoxal phosphate-dependent transferase, major region, subdomain 1)|interpro:IPR001085(Glycine hydroxymethyltransferase)|interpro:IPR019798|interpro:IPR039429	intact:EBI-2932492(chain-parent)	-	-	chain-seq-start:60|chain-seq-end:166	figure legend:ST2.2|dataset:Rare diseases - Interactions investigated in the context of Rare genetic disease|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	-	2020/12/04	2020/12/21	rogid:LCtc3OGOlk7WcLgKHle4cH3y12g9606	rogid:2dMXDgdLO6QABzj1zgHf0AlJ7dA9606	rigid:M3A1NCYdN2xC2mrF4dRFgElJ9j4	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P04004	uniprotkb:Q99757-PRO_0000034150	intact:EBI-1036653|uniprotkb:P01141|uniprotkb:Q9BSH7|uniprotkb:B2R7G0|ensembl:ENSP00000226218	intact:EBI-26565164	psi-mi:vtnc_human(display_long)|uniprotkb:VTN(gene name)|psi-mi:VTN(display_short)|uniprotkb:Serum-spreading factor(gene name synonym)|uniprotkb:V75(gene name synonym)|uniprotkb:S-protein(gene name synonym)	psi-mi:q99757-pro_0000034150(display_long)|uniprotkb:Thioredoxin-2(gene name synonym)|uniprotkb:TXN2(gene name)|psi-mi:TXN2(display_short)|uniprotkb:TRX2(gene name synonym)	psi-mi:"MI:0018"(two hybrid)	Chasapis et al. (2019)	pubmed:31018154|imex:IM-28571	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26500922|imex:IM-28571-35	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_000629.3|ensembl:ENSG00000109072(gene)|ensembl:ENST00000226218(transcript)|go:"GO:0005044"(scavenger receptor activity)|go:"GO:0005178"(integrin binding)|go:"GO:0005201"(extracellular matrix structural constituent)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0006955"(immune response)|go:"GO:0007155"(cell adhesion)|go:"GO:0007160"(cell-matrix adhesion)|go:"GO:0008201"(heparin binding)|go:"GO:0010951"(negative regulation of endopeptidase activity)|go:"GO:0014911"(positive regulation of smooth muscle cell migration)|go:"GO:0016477"(cell migration)|go:"GO:0030195"(negative regulation of blood coagulation)|go:"GO:0030247"(polysaccharide binding)|go:"GO:0030949"(positive regulation of vascular endothelial growth factor receptor signaling pathway)|go:"GO:0032092"(positive regulation of protein binding)|go:"GO:0033627"(cell adhesion mediated by integrin)|go:"GO:0035987"(endodermal cell differentiation)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0048260"(positive regulation of receptor-mediated endocytosis)|go:"GO:0050731"(positive regulation of peptidyl-tyrosine phosphorylation)|go:"GO:0061302"(smooth muscle cell-matrix adhesion)|go:"GO:0062023"(collagen-containing extracellular matrix)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071062"(alphav-beta3 integrin-vitronectin complex)|go:"GO:0072562"(blood microparticle)|go:"GO:0090303"(positive regulation of wound healing)|interpro:IPR000585(Hemopexin)|interpro:IPR001212(Somatomedin B)|interpro:IPR018486|interpro:IPR018487|interpro:IPR020436|interpro:IPR036024|interpro:IPR036375|mint:P04004|rcsb pdb:1OC0|rcsb pdb:1S4G|rcsb pdb:1SSU|rcsb pdb:2JQ8|rcsb pdb:3BT1|rcsb pdb:3BT2|rcsb pdb:4K24|rcsb pdb:6O5E|reactome:R-HSA-2129379|reactome:R-HSA-216083|reactome:R-HSA-3000170|reactome:R-HSA-3000178|reactome:R-HSA-977606|dip:DIP-36566N	intact:EBI-2932492(chain-parent)	-	-	chain-seq-start:60|chain-seq-end:166	figure legend:ST2.2|dataset:Rare diseases - Interactions investigated in the context of Rare genetic disease|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	-	2020/12/04	2020/12/21	rogid:07qxfQS6kbUZGwPyNj8/LTetT6I9606	rogid:2dMXDgdLO6QABzj1zgHf0AlJ7dA9606	rigid:H4+QmzjkWtJvjFou9rLbHubj07A	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P04644	uniprotkb:Q99757-PRO_0000034150	intact:EBI-915836|uniprotkb:Q6PDV2|ensembl:ENSRNOP00000064320	intact:EBI-26565164	psi-mi:rs17_rat(display_long)|uniprotkb:Rps17(gene name)|psi-mi:Rps17(display_short)	psi-mi:q99757-pro_0000034150(display_long)|uniprotkb:Thioredoxin-2(gene name synonym)|uniprotkb:TXN2(gene name)|psi-mi:TXN2(display_short)|uniprotkb:TRX2(gene name synonym)	psi-mi:"MI:0018"(two hybrid)	Chasapis et al. (2019)	pubmed:31018154|imex:IM-28571	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26500978|imex:IM-28571-55	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	rgd:62027|refseq:NP_058848.2|reactome:R-RNO-975956|reactome:R-RNO-975957|ensembl:ENSRNOG00000045885(gene)|ensembl:ENSRNOT00000073068(transcript)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0006364"(rRNA processing)|go:"GO:0006412"(translation)|go:"GO:0022626"(cytosolic ribosome)|go:"GO:0022627"(cytosolic small ribosomal subunit)|go:"GO:0034101"(erythrocyte homeostasis)|go:"GO:0042274"(ribosomal small subunit biogenesis)|go:"GO:0045202"(synapse)|interpro:IPR001210(Ribosomal protein S17e)|interpro:IPR018273|interpro:IPR036401|mint:P04644|reactome:R-RNO-156827|reactome:R-RNO-1799339|reactome:R-RNO-6791226|reactome:R-RNO-72649|reactome:R-RNO-72689|reactome:R-RNO-72695|reactome:R-RNO-72702|reactome:R-RNO-72706|refseq:XP_006226597.1|refseq:XP_006243666.1	intact:EBI-2932492(chain-parent)	-	-	chain-seq-start:60|chain-seq-end:166	figure legend:ST2.3|dataset:Rare diseases - Interactions investigated in the context of Rare genetic disease|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	-	2020/12/04	2020/12/21	rogid:1PxCnfXPjXqTHxn6Cb6Hplv/HeU10116	rogid:2dMXDgdLO6QABzj1zgHf0AlJ7dA9606	rigid:/Mn6SxHZ1mT8MEqueH7e+Pi4lcY	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P61023	uniprotkb:Q99757-PRO_0000034150	intact:EBI-917838|uniprotkb:Q62877|ensembl:ENSRNOP00000053243	intact:EBI-26565164	psi-mi:chp1_rat(display_long)|uniprotkb:Chp1(gene name)|psi-mi:Chp1(display_short)|uniprotkb:Calcineurin B-like protein(gene name synonym)|uniprotkb:Calcium-binding protein CHP(gene name synonym)|uniprotkb:Calcium-binding protein p22(gene name synonym)|uniprotkb:Chp(gene name synonym)|uniprotkb:EF-hand calcium-binding domain-containing protein p22(gene name synonym)	psi-mi:q99757-pro_0000034150(display_long)|uniprotkb:Thioredoxin-2(gene name synonym)|uniprotkb:TXN2(gene name)|psi-mi:TXN2(display_short)|uniprotkb:TRX2(gene name synonym)	psi-mi:"MI:0018"(two hybrid)	Chasapis et al. (2019)	pubmed:31018154|imex:IM-28571	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26500984|imex:IM-28571-37	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	rgd:620447|refseq:NP_077053.1|ensembl:ENSRNOG00000004742(gene)|ensembl:ENSRNOT00000056405(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001578"(microtubule bundle formation)|go:"GO:0001933"(negative regulation of protein phosphorylation)|go:"GO:0004860"(protein kinase inhibitor activity)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005634"(nucleus)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005793"(endoplasmic reticulum-Golgi intermediate compartment)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006469"(negative regulation of protein kinase activity)|go:"GO:0006611"(protein export from nucleus)|go:"GO:0006903"(vesicle targeting)|go:"GO:0006906"(vesicle fusion)|go:"GO:0008017"(microtubule binding)|go:"GO:0010923"(negative regulation of phosphatase activity)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0019900"(kinase binding)|go:"GO:0022406"(membrane docking)|go:"GO:0030133"(transport vesicle)|go:"GO:0031122"(cytoplasmic microtubule organization)|go:"GO:0031397"(negative regulation of protein ubiquitination)|go:"GO:0031953"(negative regulation of protein autophosphorylation)|go:"GO:0032088"(negative regulation of NF-kappaB transcription factor activity)|go:"GO:0032417"("positive regulation of sodium:proton antiporter activity")|go:"GO:0042308"(negative regulation of protein import into nucleus)|go:"GO:0048306"(calcium-dependent protein binding)|go:"GO:0050821"(protein stabilization)|go:"GO:0051222"(positive regulation of protein transport)|go:"GO:0051259"(protein complex oligomerization)|go:"GO:0051453"(regulation of intracellular pH)|go:"GO:0060050"(positive regulation of protein glycosylation)|go:"GO:0061024"(membrane organization)|go:"GO:0061025"(membrane fusion)|go:"GO:0070885"(negative regulation of calcineurin-NFAT signaling cascade)|go:"GO:0071073"(positive regulation of phospholipid biosynthetic process)|go:"GO:0071468"(cellular response to acidic pH)|go:"GO:0090314"(positive regulation of protein targeting to membrane)|go:"GO:1901214"(regulation of neuron death)|interpro:IPR002048(Calcium-binding EF-hand)|interpro:IPR011992(EF-Hand type)|interpro:IPR018247|mint:P61023|rcsb pdb:2CT9|reactome:R-RNO-2160916|go:"GO:0005737"(cytoplasm)	intact:EBI-2932492(chain-parent)	-	-	chain-seq-start:60|chain-seq-end:166	figure legend:ST2.3|dataset:Rare diseases - Interactions investigated in the context of Rare genetic disease|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	-	2020/12/04	2020/12/15	rogid:xBd8WuYr8Uekzj+ou+oU5IiBcco10116	rogid:2dMXDgdLO6QABzj1zgHf0AlJ7dA9606	rigid:Rwu9Cm+c8dnn6bY836OKOfzfv4I	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P05503	uniprotkb:Q99757-PRO_0000034150	intact:EBI-26500990|ensembl:ENSRNOP00000039048	intact:EBI-26565164	psi-mi:cox1_rat(display_long)|uniprotkb:Mtco1(gene name)|psi-mi:Mtco1(display_short)|uniprotkb:Coi(gene name synonym)|uniprotkb:mt-Co1(gene name synonym)|uniprotkb:Cytochrome c oxidase polypeptide I(gene name synonym)	psi-mi:q99757-pro_0000034150(display_long)|uniprotkb:Thioredoxin-2(gene name synonym)|uniprotkb:TXN2(gene name)|psi-mi:TXN2(display_short)|uniprotkb:TRX2(gene name synonym)	psi-mi:"MI:0018"(two hybrid)	Chasapis et al. (2019)	pubmed:31018154|imex:IM-28571	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26501024|imex:IM-28571-15	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSRNOG00000034234(gene)|ensembl:ENSRNOT00000050156(transcript)|go:"GO:0004129"(cytochrome-c oxidase activity)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005750"(mitochondrial respiratory chain complex III)|go:"GO:0005751"(mitochondrial respiratory chain complex IV)|go:"GO:0006123"(mitochondrial electron transport, cytochrome c to oxygen)|go:"GO:0006979"(response to oxidative stress)|go:"GO:0007568"(aging)|go:"GO:0009060"(aerobic respiration)|go:"GO:0015990"(electron transport coupled proton transport)|go:"GO:0020037"(heme binding)|go:"GO:0021549"(cerebellum development)|go:"GO:0022904"(respiratory electron transport chain)|go:"GO:0046688"(response to copper ion)|go:"GO:0046872"(metal ion binding)|go:"GO:0051602"(response to electrical stimulus)|interpro:IPR000883(Cytochrome c oxidase, subunit I)|interpro:IPR023615|interpro:IPR023616|interpro:IPR033944|interpro:IPR036927|mint:P05503|reactome:R-RNO-5628897|reactome:R-RNO-611105|reactome:R-RNO-9707564|go:"GO:0045277"(respiratory chain complex IV)|refseq:AP_004894.1|refseq:YP_665631.1|rgd:621871	intact:EBI-2932492(chain-parent)	-	-	chain-seq-start:60|chain-seq-end:166	figure legend:ST2.3|dataset:Rare diseases - Interactions investigated in the context of Rare genetic disease|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	-	2020/12/04	2020/12/21	rogid:Hybk67GjEK9uEUfG8iwQWkGpO9o10116	rogid:2dMXDgdLO6QABzj1zgHf0AlJ7dA9606	rigid:CJEoDdr3NmxF90boobIkbqLZJUo	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q99757-PRO_0000034150	uniprotkb:D4A314	intact:EBI-26565164	intact:EBI-26501046|ensembl:ENSRNOP00000019816	psi-mi:q99757-pro_0000034150(display_long)|uniprotkb:Thioredoxin-2(gene name synonym)|uniprotkb:TXN2(gene name)|psi-mi:TXN2(display_short)|uniprotkb:TRX2(gene name synonym)	psi-mi:d4a314_rat(display_long)|uniprotkb:Glis3(gene name)|psi-mi:Glis3(display_short)	psi-mi:"MI:0018"(two hybrid)	Chasapis et al. (2019)	pubmed:31018154|imex:IM-28571	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26501031|imex:IM-28571-57	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	intact:EBI-2932492(chain-parent)	go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR030405|interpro:IPR036236|interpro:IPR043359|mint:D4A314|ensembl:ENSRNOG00000014768(gene)|ensembl:ENSRNOT00000019816(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|rgd:1565505	-	chain-seq-start:60|chain-seq-end:166	-	figure legend:ST2.3|dataset:Rare diseases - Interactions investigated in the context of Rare genetic disease|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	-	2020/12/04	2020/12/21	rogid:2dMXDgdLO6QABzj1zgHf0AlJ7dA9606	rogid:i5c+mdNs+SUSHj1AAj17+SzGYws10116	rigid:Zx+jNiYY1hTmedBkxg+RiITvT6Y	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q99757-PRO_0000034150	uniprotkb:Q00900	intact:EBI-26565164	intact:EBI-1374455|uniprotkb:Q63725	psi-mi:q99757-pro_0000034150(display_long)|uniprotkb:Thioredoxin-2(gene name synonym)|uniprotkb:TXN2(gene name)|psi-mi:TXN2(display_short)|uniprotkb:TRX2(gene name synonym)	psi-mi:zep2_rat(display_long)|uniprotkb:Hivep2(gene name)|psi-mi:Hivep2(display_short)|uniprotkb:Agie-bp1(gene name synonym)|uniprotkb:Mibp1(gene name synonym)|uniprotkb:DNA-binding protein AGIE-BP1(gene name synonym)|uniprotkb:Angiotensinogen gene-inducible enhancer-binding protein 1(gene name synonym)|uniprotkb:Myc intron-binding protein 1(gene name synonym)	psi-mi:"MI:0018"(two hybrid)	Chasapis et al. (2019)	pubmed:31018154|imex:IM-28571	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26501070|imex:IM-28571-17	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	intact:EBI-2932492(chain-parent)	rgd:61988|refseq:NP_077051.1|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR036236|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|mint:Q00900	-	chain-seq-start:60|chain-seq-end:166	-	figure legend:ST2.3|dataset:Rare diseases - Interactions investigated in the context of Rare genetic disease|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	-	2020/12/04	2020/12/21	rogid:2dMXDgdLO6QABzj1zgHf0AlJ7dA9606	rogid:eeXigOZpFmIiVYU72ack+PcKLl410116	rigid:P230I2Bywz75MKODyoftHKaMSkY	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q4JFL8	uniprotkb:Q99757-PRO_0000034150	intact:EBI-26501076	intact:EBI-26565164	psi-mi:q4jfl8_rat(display_long)|uniprotkb:LAR-PTP2(gene name)|psi-mi:LAR-PTP2(display_short)	psi-mi:q99757-pro_0000034150(display_long)|uniprotkb:Thioredoxin-2(gene name synonym)|uniprotkb:TXN2(gene name)|psi-mi:TXN2(display_short)|uniprotkb:TRX2(gene name synonym)	psi-mi:"MI:0018"(two hybrid)	Chasapis et al. (2019)	pubmed:31018154|imex:IM-28571	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26501096|imex:IM-28571-39	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	go:"GO:0004725"(protein tyrosine phosphatase activity)|go:"GO:0016021"(integral component of membrane)|mint:Q4JFL8|interpro:IPR003961(Fibronectin, type III)|interpro:IPR036116|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR036179|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR013098(Immunoglobulin I-set)|interpro:IPR003599(Immunoglobulin subtype)|interpro:IPR003598(Immunoglobulin subtype 2)|interpro:IPR029021|interpro:IPR000242(Protein-tyrosine phosphatase, receptor/non-receptor type)|interpro:IPR016130(Protein-tyrosine phosphatase, active site)|interpro:IPR003595(Protein-tyrosine phosphatase, catalytic)|interpro:IPR000387(Protein-tyrosine phosphatase)	intact:EBI-2932492(chain-parent)	-	-	chain-seq-start:60|chain-seq-end:166	figure legend:ST2.3|dataset:Rare diseases - Interactions investigated in the context of Rare genetic disease|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	-	2020/12/04	2020/12/21	rogid:XMUG70AKqgf4ZGazlpqfIRtPJL810116	rogid:2dMXDgdLO6QABzj1zgHf0AlJ7dA9606	rigid:UPcFswEBSUsRRiVLaL3/4JD83M4	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q78P75	uniprotkb:Q99757-PRO_0000034150	intact:EBI-7619533|intact:MINT-4577592|ensembl:ENSRNOP00000012279	intact:EBI-26565164	psi-mi:dyl2_rat(display_long)|uniprotkb:Dynll2(gene name)|psi-mi:Dynll2(display_short)|uniprotkb:Dlc2(gene name synonym)|uniprotkb:Dynein light chain LC8-type 2(gene name synonym)	psi-mi:q99757-pro_0000034150(display_long)|uniprotkb:Thioredoxin-2(gene name synonym)|uniprotkb:TXN2(gene name)|psi-mi:TXN2(display_short)|uniprotkb:TRX2(gene name synonym)	psi-mi:"MI:0018"(two hybrid)	Chasapis et al. (2019)	pubmed:31018154|imex:IM-28571	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26501103|imex:IM-28571-19	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_542428.1|rgd:619860|ensembl:ENSRNOG00000008921(gene)|ensembl:ENSRNOT00000012279(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005868"(cytoplasmic dynein complex)|go:"GO:0005874"(microtubule)|go:"GO:0007017"(microtubule-based process)|go:"GO:0014069"(postsynaptic density)|go:"GO:0030286"(dynein complex)|go:"GO:0031475"(myosin V complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045505"(dynein intermediate chain binding)|go:"GO:0051959"(dynein light intermediate chain binding)|go:"GO:0060271"(cilium assembly)|go:"GO:0097110"(scaffold protein binding)|go:"GO:0097731"(9+0 non-motile cilium)|go:"GO:0098794"(postsynapse)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:2000582"(obsolete positive regulation of microtubule motor activity, plus-end-directed)|interpro:IPR001372(Dynein light chain, type 1 and 2)|interpro:IPR019763|interpro:IPR037177|mint:Q78P75|rcsb pdb:1PWJ|rcsb pdb:1PWK|reactome:R-RNO-139910|reactome:R-RNO-141444|reactome:R-RNO-1632852|reactome:R-RNO-2132295|reactome:R-RNO-2467813|reactome:R-RNO-2500257|reactome:R-RNO-3371497|reactome:R-RNO-5620924|reactome:R-RNO-5663220|reactome:R-RNO-6807878|reactome:R-RNO-6811436|reactome:R-RNO-68877|reactome:R-RNO-9646399|reactome:R-RNO-9648025|refseq:XP_006247139.1	intact:EBI-2932492(chain-parent)	-	comment:mint|function:May be involved in some aspects of dynein-related intracellular transport and motility. May play a role in changing or maintaining the spatial distribution of cytoskeletal structures	chain-seq-start:60|chain-seq-end:166	figure legend:ST2.3|dataset:Rare diseases - Interactions investigated in the context of Rare genetic disease|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae)	-	2020/12/04	2020/12/21	rogid:4RFpJF40RBja5mOvt/aCv3miiDU10116	rogid:2dMXDgdLO6QABzj1zgHf0AlJ7dA9606	rigid:x/skyf0B0CtoFrqLj+ep+07nYqM	false	-	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)