#ID(s) interactor A ID(s) interactor B Alt. ID(s) interactor A Alt. ID(s) interactor B Alias(es) interactor A Alias(es) interactor B Interaction detection method(s) Publication 1st author(s) Publication Identifier(s) Taxid interactor A Taxid interactor B Interaction type(s) Source database(s) Interaction identifier(s) Confidence value(s) Expansion method(s) Biological role(s) interactor A Biological role(s) interactor B Experimental role(s) interactor A Experimental role(s) interactor B Type(s) interactor A Type(s) interactor B Xref(s) interactor A Xref(s) interactor B Interaction Xref(s) Annotation(s) interactor A Annotation(s) interactor B Interaction annotation(s) Host organism(s) Interaction parameter(s) Creation date Update date Checksum(s) interactor A Checksum(s) interactor B Interaction Checksum(s) Negative Feature(s) interactor A Feature(s) interactor B Stoichiometry(s) interactor A Stoichiometry(s) interactor B Identification method participant A Identification method participant B uniprotkb:Q01628 uniprotkb:O95415 intact:EBI-7932862|uniprotkb:Q96HK8|uniprotkb:Q53Y76|uniprotkb:Q96J15|intact:MINT-2805186|ensembl:ENSP00000382707 intact:EBI-2874789|ensembl:ENSP00000297290|uniprotkb:Q8WV52|uniprotkb:Q9UIC6|uniprotkb:D6W5R8|intact:EBI-25504307|uniprotkb:F5GXW6|intact:EBI-25591918 psi-mi:ifm3_human(display_long)|uniprotkb:IFITM3(gene name)|psi-mi:IFITM3(display_short)|uniprotkb:Dispanin subfamily A member 2b(gene name synonym)|uniprotkb:Interferon-inducible protein 1-8U(gene name synonym) psi-mi:bri3_human(display_long)|uniprotkb:BRI3(gene name)|psi-mi:BRI3(display_short)|uniprotkb:pRGR2(gene name synonym) psi-mi:"MI:0018"(two hybrid) Akiva et al. (2017) pubmed:30983867|imex:IM-27875 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-25503997|imex:IM-27875-1 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_066362.2|ensembl:ENSG00000142089(gene)|ensembl:ENST00000399808(transcript)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005886"(plasma membrane)|go:"GO:0006955"(immune response)|go:"GO:0016021"(integral component of membrane)|go:"GO:0031901"(early endosome membrane)|go:"GO:0031902"(late endosome membrane)|go:"GO:0032897"(negative regulation of viral transcription)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034341"(response to interferon-gamma)|go:"GO:0035455"(response to interferon-alpha)|go:"GO:0035456"(response to interferon-beta)|go:"GO:0045071"(negative regulation of viral genome replication)|go:"GO:0046597"(negative regulation of viral entry into host cell)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051607"(defense response to virus)|go:"GO:0060337"(type I interferon signaling pathway)|interpro:IPR007593(Interferon-induced transmembrane protein)|mint:Q01628|reactome:R-HSA-909733|go:"GO:0009615"(response to virus) ensembl:ENSG00000164713(gene)|ensembl:ENST00000297290(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005886"(plasma membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0035577"(azurophil granule membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|interpro:IPR019317|reactome:R-HSA-6798695|ensembl:ENSP00000297290|ensembl:ENST00000539286|ensembl:ENSP00000440936|refseq:NP_056194.1|refseq:NP_001152963.1 - comment:mint isoform-comment:The authors do not mention which isoform has been used to transform the bait strain. figure legend:1a, suppl. table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) - 2020/04/04 2020/04/06 rogid:jR3B3HZZPwQAA1ccX0QeKYqa2449606 rogid:SOr81TwyfludaXvnbnQNtIIBpQM9606 rigid:0CFYz38Sv9+ZaJm6/In3KDb4WIA false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:P26572 uniprotkb:O95415 intact:EBI-7211952|uniprotkb:B3KRU8|intact:MINT-4902561|uniprotkb:A8K404|intact:MINT-1196185|uniprotkb:Q6IBE3|uniprotkb:D3DWR1|intact:EBI-7263344|ensembl:ENSP00000311888|ensembl:ENSP00000332073|ensembl:ENSP00000377010|ensembl:ENSP00000402838|ensembl:ENSP00000404718 intact:EBI-2874789|ensembl:ENSP00000297290|uniprotkb:Q8WV52|uniprotkb:Q9UIC6|uniprotkb:D6W5R8|intact:EBI-25504307|uniprotkb:F5GXW6|intact:EBI-25591918 psi-mi:mgat1_human(display_long)|uniprotkb:MGAT1(gene name)|psi-mi:MGAT1(display_short)|uniprotkb:GGNT1(gene name synonym)|uniprotkb:GLCT1(gene name synonym)|uniprotkb:MGAT(gene name synonym)|uniprotkb:GLYT1(gene name synonym)|uniprotkb:N-glycosyl-oligosaccharide-glycoprotein N-acetylglucosaminyltransferase I(gene name synonym) psi-mi:bri3_human(display_long)|uniprotkb:BRI3(gene name)|psi-mi:BRI3(display_short)|uniprotkb:pRGR2(gene name synonym) psi-mi:"MI:0018"(two hybrid) Akiva et al. (2017) pubmed:30983867|imex:IM-27875 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-25504004|imex:IM-27875-3 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:XP_011532861.1|refseq:XP_011532862.1|refseq:XP_011532863.1|refseq:XP_011532864.1|refseq:XP_011532865.1|refseq:XP_005265972.1|refseq:XP_005265973.1|refseq:NP_001108090.1|refseq:NP_001108089.1|refseq:NP_001108091.1|refseq:NP_001108092.1|refseq:NP_002397.2|ensembl:ENSG00000131446(gene)|ensembl:ENST00000307826(transcript)|ensembl:ENST00000333055(transcript)|ensembl:ENST00000393340(transcript)|ensembl:ENST00000427865(transcript)|ensembl:ENST00000446023(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0003827"(alpha-1,3-mannosylglycoprotein 2-beta-N-acetylglucosaminyltransferase activity)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0006049"(UDP-N-acetylglucosamine catabolic process)|go:"GO:0006486"(protein glycosylation)|go:"GO:0006487"(protein N-linked glycosylation)|go:"GO:0008375"(acetylglucosaminyltransferase activity)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0018279"(protein N-linked glycosylation via asparagine)|go:"GO:0019082"(viral protein processing)|go:"GO:0030145"(manganese ion binding)|go:"GO:0033116"(endoplasmic reticulum-Golgi intermediate compartment membrane)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0070062"(extracellular exosome)|go:"GO:1903561"(extracellular vesicle)|interpro:IPR004139(Glycosyl transferase, family 13)|interpro:IPR029044|reactome:R-HSA-964739|reactome:R-HSA-9683686|reactome:R-HSA-9694548|refseq:XP_016864975.1|refseq:XP_016864976.1|refseq:XP_006714929.1 ensembl:ENSG00000164713(gene)|ensembl:ENST00000297290(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005886"(plasma membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0035577"(azurophil granule membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|interpro:IPR019317|reactome:R-HSA-6798695|ensembl:ENSP00000297290|ensembl:ENST00000539286|ensembl:ENSP00000440936|refseq:NP_056194.1|refseq:NP_001152963.1 - function:Initiates complex N-linked carbohydrate formation. Essential for the conversion of high-mannose to hybrid and complex N-glycans|comment:mint|comment:homomint - figure legend:1a, suppl. table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) - 2020/04/04 2020/04/06 rogid:2v7q3/Hu+V0aAylAQ6VMVMHeS6c9606 rogid:SOr81TwyfludaXvnbnQNtIIBpQM9606 rigid:Q/JRZNAgZpLQ+G+gLHh30JkmbFY false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:P16871 uniprotkb:O95415 intact:EBI-80490|uniprotkb:Q6NSP4|ensembl:ENSP00000306157|uniprotkb:Q6SV45|uniprotkb:Q9UPC1|uniprotkb:B2RCS6|uniprotkb:Q6NWM0|uniprotkb:B4DVT1|uniprotkb:Q05CU8|uniprotkb:Q6NWM1|uniprotkb:Q6NWM2|uniprotkb:Q6NWM3 intact:EBI-2874789|ensembl:ENSP00000297290|uniprotkb:Q8WV52|uniprotkb:Q9UIC6|uniprotkb:D6W5R8|intact:EBI-25504307|uniprotkb:F5GXW6|intact:EBI-25591918 psi-mi:il7ra_human(display_long)|uniprotkb:IL7R(gene name)|psi-mi:IL7R(display_short)|uniprotkb:CDw127(gene name synonym) psi-mi:bri3_human(display_long)|uniprotkb:BRI3(gene name)|psi-mi:BRI3(display_short)|uniprotkb:pRGR2(gene name synonym) psi-mi:"MI:0018"(two hybrid) Akiva et al. (2017) pubmed:30983867|imex:IM-27875 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-25507926|imex:IM-27875-24 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000168685(gene)|ensembl:ENST00000303115(transcript)|go:"GO:0000018"(regulation of DNA recombination)|go:"GO:0000902"(cell morphogenesis)|go:"GO:0001915"(negative regulation of T cell mediated cytotoxicity)|go:"GO:0003823"(antigen binding)|go:"GO:0004896"(cytokine receptor activity)|go:"GO:0004917"(interleukin-7 receptor activity)|go:"GO:0005576"(extracellular region)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006955"(immune response)|go:"GO:0007165"(signal transduction)|go:"GO:0007166"(cell surface receptor signaling pathway)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0008361"(regulation of cell size)|go:"GO:0009897"(external side of plasma membrane)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030217"(T cell differentiation)|go:"GO:0030669"(clathrin-coated endocytic vesicle membrane)|go:"GO:0033089"(positive regulation of T cell differentiation in thymus)|go:"GO:0042100"(B cell proliferation)|go:"GO:0048535"(lymph node development)|go:"GO:0048872"(homeostasis of number of cells)|go:"GO:0050830"(defense response to Gram-positive bacterium)|go:"GO:0070233"(negative regulation of T cell apoptotic process)|go:"GO:1904894"(positive regulation of receptor signaling pathway via STAT)|interpro:IPR003531(Short hematopoietin receptor, family 1, conserved site)|interpro:IPR003961(Fibronectin, type III)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR036116|interpro:IPR040997|mint:P16871|rcsb pdb:3DI2|rcsb pdb:3DI3|go:"GO:0005886"(plasma membrane)|rcsb pdb:5J11|rcsb pdb:6P50|rcsb pdb:6P67|reactome:R-HSA-1266695|reactome:R-HSA-8856825|reactome:R-HSA-8856828|rcsb pdb:3UP1|refseq:NP_002176.2|dip:DIP-3045N ensembl:ENSG00000164713(gene)|ensembl:ENST00000297290(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005886"(plasma membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0035577"(azurophil granule membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|interpro:IPR019317|reactome:R-HSA-6798695|ensembl:ENSP00000297290|ensembl:ENST00000539286|ensembl:ENSP00000440936|refseq:NP_056194.1|refseq:NP_001152963.1 - - - figure legend:1a, suppl. table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) - 2020/04/04 2020/04/09 rogid:8tfp5J+GYGrnzfuyfJhj8T+IMt89606 rogid:SOr81TwyfludaXvnbnQNtIIBpQM9606 rigid:o0QoDsXn5MAM3wsBATgHzlCp3s4 false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q01628 uniprotkb:O95415 intact:EBI-7932862|uniprotkb:Q96HK8|uniprotkb:Q53Y76|uniprotkb:Q96J15|intact:MINT-2805186|ensembl:ENSP00000382707 intact:EBI-2874789|ensembl:ENSP00000297290|uniprotkb:Q8WV52|uniprotkb:Q9UIC6|uniprotkb:D6W5R8|intact:EBI-25504307|uniprotkb:F5GXW6|intact:EBI-25591918 psi-mi:ifm3_human(display_long)|uniprotkb:IFITM3(gene name)|psi-mi:IFITM3(display_short)|uniprotkb:Dispanin subfamily A member 2b(gene name synonym)|uniprotkb:Interferon-inducible protein 1-8U(gene name synonym) psi-mi:bri3_human(display_long)|uniprotkb:BRI3(gene name)|psi-mi:BRI3(display_short)|uniprotkb:pRGR2(gene name synonym) psi-mi:"MI:0018"(two hybrid) Akiva et al. (2017) pubmed:30983867|imex:IM-27875 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-25509322|imex:IM-27875-26 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_066362.2|ensembl:ENSG00000142089(gene)|ensembl:ENST00000399808(transcript)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005886"(plasma membrane)|go:"GO:0006955"(immune response)|go:"GO:0016021"(integral component of membrane)|go:"GO:0031901"(early endosome membrane)|go:"GO:0031902"(late endosome membrane)|go:"GO:0032897"(negative regulation of viral transcription)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034341"(response to interferon-gamma)|go:"GO:0035455"(response to interferon-alpha)|go:"GO:0035456"(response to interferon-beta)|go:"GO:0045071"(negative regulation of viral genome replication)|go:"GO:0046597"(negative regulation of viral entry into host cell)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051607"(defense response to virus)|go:"GO:0060337"(type I interferon signaling pathway)|interpro:IPR007593(Interferon-induced transmembrane protein)|mint:Q01628|reactome:R-HSA-909733|go:"GO:0009615"(response to virus) ensembl:ENSG00000164713(gene)|ensembl:ENST00000297290(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005886"(plasma membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0035577"(azurophil granule membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|interpro:IPR019317|reactome:R-HSA-6798695|ensembl:ENSP00000297290|ensembl:ENST00000539286|ensembl:ENSP00000440936|refseq:NP_056194.1|refseq:NP_001152963.1 - comment:mint isoform-comment:The authors do not mention which isoform has been used to transform the bait strain. figure legend:1b|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) - 2020/04/04 2020/04/13 rogid:jR3B3HZZPwQAA1ccX0QeKYqa2449606 rogid:SOr81TwyfludaXvnbnQNtIIBpQM9606 rigid:0CFYz38Sv9+ZaJm6/In3KDb4WIA false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:P26572 uniprotkb:O95415 intact:EBI-7211952|uniprotkb:B3KRU8|intact:MINT-4902561|uniprotkb:A8K404|intact:MINT-1196185|uniprotkb:Q6IBE3|uniprotkb:D3DWR1|intact:EBI-7263344|ensembl:ENSP00000311888|ensembl:ENSP00000332073|ensembl:ENSP00000377010|ensembl:ENSP00000402838|ensembl:ENSP00000404718 intact:EBI-2874789|ensembl:ENSP00000297290|uniprotkb:Q8WV52|uniprotkb:Q9UIC6|uniprotkb:D6W5R8|intact:EBI-25504307|uniprotkb:F5GXW6|intact:EBI-25591918 psi-mi:mgat1_human(display_long)|uniprotkb:MGAT1(gene name)|psi-mi:MGAT1(display_short)|uniprotkb:GGNT1(gene name synonym)|uniprotkb:GLCT1(gene name synonym)|uniprotkb:MGAT(gene name synonym)|uniprotkb:GLYT1(gene name synonym)|uniprotkb:N-glycosyl-oligosaccharide-glycoprotein N-acetylglucosaminyltransferase I(gene name synonym) psi-mi:bri3_human(display_long)|uniprotkb:BRI3(gene name)|psi-mi:BRI3(display_short)|uniprotkb:pRGR2(gene name synonym) psi-mi:"MI:0018"(two hybrid) Akiva et al. (2017) pubmed:30983867|imex:IM-27875 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-25509330|imex:IM-27875-28 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:XP_011532861.1|refseq:XP_011532862.1|refseq:XP_011532863.1|refseq:XP_011532864.1|refseq:XP_011532865.1|refseq:XP_005265972.1|refseq:XP_005265973.1|refseq:NP_001108090.1|refseq:NP_001108089.1|refseq:NP_001108091.1|refseq:NP_001108092.1|refseq:NP_002397.2|ensembl:ENSG00000131446(gene)|ensembl:ENST00000307826(transcript)|ensembl:ENST00000333055(transcript)|ensembl:ENST00000393340(transcript)|ensembl:ENST00000427865(transcript)|ensembl:ENST00000446023(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0003827"(alpha-1,3-mannosylglycoprotein 2-beta-N-acetylglucosaminyltransferase activity)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0006049"(UDP-N-acetylglucosamine catabolic process)|go:"GO:0006486"(protein glycosylation)|go:"GO:0006487"(protein N-linked glycosylation)|go:"GO:0008375"(acetylglucosaminyltransferase activity)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0018279"(protein N-linked glycosylation via asparagine)|go:"GO:0019082"(viral protein processing)|go:"GO:0030145"(manganese ion binding)|go:"GO:0033116"(endoplasmic reticulum-Golgi intermediate compartment membrane)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0070062"(extracellular exosome)|go:"GO:1903561"(extracellular vesicle)|interpro:IPR004139(Glycosyl transferase, family 13)|interpro:IPR029044|reactome:R-HSA-964739|reactome:R-HSA-9683686|reactome:R-HSA-9694548|refseq:XP_016864975.1|refseq:XP_016864976.1|refseq:XP_006714929.1 ensembl:ENSG00000164713(gene)|ensembl:ENST00000297290(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005886"(plasma membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0035577"(azurophil granule membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|interpro:IPR019317|reactome:R-HSA-6798695|ensembl:ENSP00000297290|ensembl:ENST00000539286|ensembl:ENSP00000440936|refseq:NP_056194.1|refseq:NP_001152963.1 - function:Initiates complex N-linked carbohydrate formation. Essential for the conversion of high-mannose to hybrid and complex N-glycans|comment:mint|comment:homomint - figure legend:1b|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) - 2020/04/04 2020/04/13 rogid:2v7q3/Hu+V0aAylAQ6VMVMHeS6c9606 rogid:SOr81TwyfludaXvnbnQNtIIBpQM9606 rigid:Q/JRZNAgZpLQ+G+gLHh30JkmbFY false - - - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q01628 uniprotkb:O95415 intact:EBI-7932862|uniprotkb:Q96HK8|uniprotkb:Q53Y76|uniprotkb:Q96J15|intact:MINT-2805186|ensembl:ENSP00000382707 intact:EBI-2874789|ensembl:ENSP00000297290|uniprotkb:Q8WV52|uniprotkb:Q9UIC6|uniprotkb:D6W5R8|intact:EBI-25504307|uniprotkb:F5GXW6|intact:EBI-25591918 psi-mi:ifm3_human(display_long)|uniprotkb:IFITM3(gene name)|psi-mi:IFITM3(display_short)|uniprotkb:Dispanin subfamily A member 2b(gene name synonym)|uniprotkb:Interferon-inducible protein 1-8U(gene name synonym) psi-mi:bri3_human(display_long)|uniprotkb:BRI3(gene name)|psi-mi:BRI3(display_short)|uniprotkb:pRGR2(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Akiva et al. (2017) pubmed:30983867|imex:IM-27875 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-25504163|imex:IM-27875-5 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_066362.2|ensembl:ENSG00000142089(gene)|ensembl:ENST00000399808(transcript)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005886"(plasma membrane)|go:"GO:0006955"(immune response)|go:"GO:0016021"(integral component of membrane)|go:"GO:0031901"(early endosome membrane)|go:"GO:0031902"(late endosome membrane)|go:"GO:0032897"(negative regulation of viral transcription)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034341"(response to interferon-gamma)|go:"GO:0035455"(response to interferon-alpha)|go:"GO:0035456"(response to interferon-beta)|go:"GO:0045071"(negative regulation of viral genome replication)|go:"GO:0046597"(negative regulation of viral entry into host cell)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051607"(defense response to virus)|go:"GO:0060337"(type I interferon signaling pathway)|interpro:IPR007593(Interferon-induced transmembrane protein)|mint:Q01628|reactome:R-HSA-909733|go:"GO:0009615"(response to virus) ensembl:ENSG00000164713(gene)|ensembl:ENST00000297290(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005886"(plasma membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0035577"(azurophil granule membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|interpro:IPR019317|reactome:R-HSA-6798695|ensembl:ENSP00000297290|ensembl:ENST00000539286|ensembl:ENSP00000440936|refseq:NP_056194.1|refseq:NP_001152963.1 - comment:mint - figure legend:3a, suppl.1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/04/04 2020/06/19 rogid:jR3B3HZZPwQAA1ccX0QeKYqa2449606 rogid:SOr81TwyfludaXvnbnQNtIIBpQM9606 rigid:0CFYz38Sv9+ZaJm6/In3KDb4WIA false ha tag:?-? green fluorescent protein tag:?-? - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:P26572 uniprotkb:O95415 intact:EBI-7211952|uniprotkb:B3KRU8|intact:MINT-4902561|uniprotkb:A8K404|intact:MINT-1196185|uniprotkb:Q6IBE3|uniprotkb:D3DWR1|intact:EBI-7263344|ensembl:ENSP00000311888|ensembl:ENSP00000332073|ensembl:ENSP00000377010|ensembl:ENSP00000402838|ensembl:ENSP00000404718 intact:EBI-2874789|ensembl:ENSP00000297290|uniprotkb:Q8WV52|uniprotkb:Q9UIC6|uniprotkb:D6W5R8|intact:EBI-25504307|uniprotkb:F5GXW6|intact:EBI-25591918 psi-mi:mgat1_human(display_long)|uniprotkb:MGAT1(gene name)|psi-mi:MGAT1(display_short)|uniprotkb:GGNT1(gene name synonym)|uniprotkb:GLCT1(gene name synonym)|uniprotkb:MGAT(gene name synonym)|uniprotkb:GLYT1(gene name synonym)|uniprotkb:N-glycosyl-oligosaccharide-glycoprotein N-acetylglucosaminyltransferase I(gene name synonym) psi-mi:bri3_human(display_long)|uniprotkb:BRI3(gene name)|psi-mi:BRI3(display_short)|uniprotkb:pRGR2(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Akiva et al. (2017) pubmed:30983867|imex:IM-27875 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-25504183|imex:IM-27875-7 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:XP_011532861.1|refseq:XP_011532862.1|refseq:XP_011532863.1|refseq:XP_011532864.1|refseq:XP_011532865.1|refseq:XP_005265972.1|refseq:XP_005265973.1|refseq:NP_001108090.1|refseq:NP_001108089.1|refseq:NP_001108091.1|refseq:NP_001108092.1|refseq:NP_002397.2|ensembl:ENSG00000131446(gene)|ensembl:ENST00000307826(transcript)|ensembl:ENST00000333055(transcript)|ensembl:ENST00000393340(transcript)|ensembl:ENST00000427865(transcript)|ensembl:ENST00000446023(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0003827"(alpha-1,3-mannosylglycoprotein 2-beta-N-acetylglucosaminyltransferase activity)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0006049"(UDP-N-acetylglucosamine catabolic process)|go:"GO:0006486"(protein glycosylation)|go:"GO:0006487"(protein N-linked glycosylation)|go:"GO:0008375"(acetylglucosaminyltransferase activity)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0018279"(protein N-linked glycosylation via asparagine)|go:"GO:0019082"(viral protein processing)|go:"GO:0030145"(manganese ion binding)|go:"GO:0033116"(endoplasmic reticulum-Golgi intermediate compartment membrane)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0070062"(extracellular exosome)|go:"GO:1903561"(extracellular vesicle)|interpro:IPR004139(Glycosyl transferase, family 13)|interpro:IPR029044|reactome:R-HSA-964739|reactome:R-HSA-9683686|reactome:R-HSA-9694548|refseq:XP_016864975.1|refseq:XP_016864976.1|refseq:XP_006714929.1 ensembl:ENSG00000164713(gene)|ensembl:ENST00000297290(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005886"(plasma membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0035577"(azurophil granule membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|interpro:IPR019317|reactome:R-HSA-6798695|ensembl:ENSP00000297290|ensembl:ENST00000539286|ensembl:ENSP00000440936|refseq:NP_056194.1|refseq:NP_001152963.1 - function:Initiates complex N-linked carbohydrate formation. Essential for the conversion of high-mannose to hybrid and complex N-glycans|comment:mint|comment:homomint - figure legend:3a, suppl.1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/04/04 2020/04/07 rogid:2v7q3/Hu+V0aAylAQ6VMVMHeS6c9606 rogid:SOr81TwyfludaXvnbnQNtIIBpQM9606 rigid:Q/JRZNAgZpLQ+G+gLHh30JkmbFY false ha tag:?-? green fluorescent protein tag:?-? - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:Q8WY22 uniprotkb:O95415 intact:EBI-359348|uniprotkb:Q8WY23|ensembl:ENSP00000340761|ensembl:ENSP00000500359 intact:EBI-2874789|ensembl:ENSP00000297290|uniprotkb:Q8WV52|uniprotkb:Q9UIC6|uniprotkb:D6W5R8|intact:EBI-25504307|uniprotkb:F5GXW6|intact:EBI-25591918 psi-mi:bri3b_human(display_long)|uniprotkb:BRI3BP(gene name)|psi-mi:BRI3BP(display_short)|uniprotkb:KG19(gene name synonym)|uniprotkb:Cervical cancer 1 proto-oncogene-binding protein KG19(gene name synonym)|uniprotkb:HCCRBP-1(gene name synonym) psi-mi:bri3_human(display_long)|uniprotkb:BRI3(gene name)|psi-mi:BRI3(display_short)|uniprotkb:pRGR2(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Akiva et al. (2017) pubmed:30983867|imex:IM-27875 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-25504211|imex:IM-27875-9 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_542193.3|ensembl:ENSG00000184992(gene)|ensembl:ENST00000341446(transcript)|ensembl:ENST00000672415(transcript)|go:"GO:0005739"(mitochondrion)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0016021"(integral component of membrane)|interpro:IPR033367 ensembl:ENSG00000164713(gene)|ensembl:ENST00000297290(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005886"(plasma membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0035577"(azurophil granule membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|interpro:IPR019317|reactome:R-HSA-6798695|ensembl:ENSP00000297290|ensembl:ENST00000539286|ensembl:ENSP00000440936|refseq:NP_056194.1|refseq:NP_001152963.1 - - - figure legend:3a, suppl.1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/04/04 2020/06/19 rogid:O9epHcfM1m7xNvrm6ELo0fRRGV49606 rogid:SOr81TwyfludaXvnbnQNtIIBpQM9606 rigid:uW0HebLCiYr0hdPh3nX9UGyjws4 false ha tag:?-? green fluorescent protein tag:?-? - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:Q01628 uniprotkb:O95415 intact:EBI-7932862|uniprotkb:Q96HK8|uniprotkb:Q53Y76|uniprotkb:Q96J15|intact:MINT-2805186|ensembl:ENSP00000382707 intact:EBI-2874789|ensembl:ENSP00000297290|uniprotkb:Q8WV52|uniprotkb:Q9UIC6|uniprotkb:D6W5R8|intact:EBI-25504307|uniprotkb:F5GXW6|intact:EBI-25591918 psi-mi:ifm3_human(display_long)|uniprotkb:IFITM3(gene name)|psi-mi:IFITM3(display_short)|uniprotkb:Dispanin subfamily A member 2b(gene name synonym)|uniprotkb:Interferon-inducible protein 1-8U(gene name synonym) psi-mi:bri3_human(display_long)|uniprotkb:BRI3(gene name)|psi-mi:BRI3(display_short)|uniprotkb:pRGR2(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Akiva et al. (2017) pubmed:30983867|imex:IM-27875 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-25504343|imex:IM-27875-21 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_066362.2|ensembl:ENSG00000142089(gene)|ensembl:ENST00000399808(transcript)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005886"(plasma membrane)|go:"GO:0006955"(immune response)|go:"GO:0016021"(integral component of membrane)|go:"GO:0031901"(early endosome membrane)|go:"GO:0031902"(late endosome membrane)|go:"GO:0032897"(negative regulation of viral transcription)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034341"(response to interferon-gamma)|go:"GO:0035455"(response to interferon-alpha)|go:"GO:0035456"(response to interferon-beta)|go:"GO:0045071"(negative regulation of viral genome replication)|go:"GO:0046597"(negative regulation of viral entry into host cell)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051607"(defense response to virus)|go:"GO:0060337"(type I interferon signaling pathway)|interpro:IPR007593(Interferon-induced transmembrane protein)|mint:Q01628|reactome:R-HSA-909733|go:"GO:0009615"(response to virus) ensembl:ENSG00000164713(gene)|ensembl:ENST00000297290(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005886"(plasma membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0035577"(azurophil granule membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|interpro:IPR019317|reactome:R-HSA-6798695|ensembl:ENSP00000297290|ensembl:ENST00000539286|ensembl:ENSP00000440936|refseq:NP_056194.1|refseq:NP_001152963.1 - comment:mint - figure legend:3b|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/04/04 2020/08/14 rogid:jR3B3HZZPwQAA1ccX0QeKYqa2449606 rogid:SOr81TwyfludaXvnbnQNtIIBpQM9606 rigid:0CFYz38Sv9+ZaJm6/In3KDb4WIA false ha tag:?-? green fluorescent protein tag:?-? - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:P26572 uniprotkb:O95415 intact:EBI-7211952|uniprotkb:B3KRU8|intact:MINT-4902561|uniprotkb:A8K404|intact:MINT-1196185|uniprotkb:Q6IBE3|uniprotkb:D3DWR1|intact:EBI-7263344|ensembl:ENSP00000311888|ensembl:ENSP00000332073|ensembl:ENSP00000377010|ensembl:ENSP00000402838|ensembl:ENSP00000404718 intact:EBI-2874789|ensembl:ENSP00000297290|uniprotkb:Q8WV52|uniprotkb:Q9UIC6|uniprotkb:D6W5R8|intact:EBI-25504307|uniprotkb:F5GXW6|intact:EBI-25591918 psi-mi:mgat1_human(display_long)|uniprotkb:MGAT1(gene name)|psi-mi:MGAT1(display_short)|uniprotkb:GGNT1(gene name synonym)|uniprotkb:GLCT1(gene name synonym)|uniprotkb:MGAT(gene name synonym)|uniprotkb:GLYT1(gene name synonym)|uniprotkb:N-glycosyl-oligosaccharide-glycoprotein N-acetylglucosaminyltransferase I(gene name synonym) psi-mi:bri3_human(display_long)|uniprotkb:BRI3(gene name)|psi-mi:BRI3(display_short)|uniprotkb:pRGR2(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Akiva et al. (2017) pubmed:30983867|imex:IM-27875 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-25504352|imex:IM-27875-11 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:XP_011532861.1|refseq:XP_011532862.1|refseq:XP_011532863.1|refseq:XP_011532864.1|refseq:XP_011532865.1|refseq:XP_005265972.1|refseq:XP_005265973.1|refseq:NP_001108090.1|refseq:NP_001108089.1|refseq:NP_001108091.1|refseq:NP_001108092.1|refseq:NP_002397.2|ensembl:ENSG00000131446(gene)|ensembl:ENST00000307826(transcript)|ensembl:ENST00000333055(transcript)|ensembl:ENST00000393340(transcript)|ensembl:ENST00000427865(transcript)|ensembl:ENST00000446023(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0003827"(alpha-1,3-mannosylglycoprotein 2-beta-N-acetylglucosaminyltransferase activity)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0006049"(UDP-N-acetylglucosamine catabolic process)|go:"GO:0006486"(protein glycosylation)|go:"GO:0006487"(protein N-linked glycosylation)|go:"GO:0008375"(acetylglucosaminyltransferase activity)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0018279"(protein N-linked glycosylation via asparagine)|go:"GO:0019082"(viral protein processing)|go:"GO:0030145"(manganese ion binding)|go:"GO:0033116"(endoplasmic reticulum-Golgi intermediate compartment membrane)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0070062"(extracellular exosome)|go:"GO:1903561"(extracellular vesicle)|interpro:IPR004139(Glycosyl transferase, family 13)|interpro:IPR029044|reactome:R-HSA-964739|reactome:R-HSA-9683686|reactome:R-HSA-9694548|refseq:XP_016864975.1|refseq:XP_016864976.1|refseq:XP_006714929.1 ensembl:ENSG00000164713(gene)|ensembl:ENST00000297290(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005886"(plasma membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0035577"(azurophil granule membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|interpro:IPR019317|reactome:R-HSA-6798695|ensembl:ENSP00000297290|ensembl:ENST00000539286|ensembl:ENSP00000440936|refseq:NP_056194.1|refseq:NP_001152963.1 - function:Initiates complex N-linked carbohydrate formation. Essential for the conversion of high-mannose to hybrid and complex N-glycans|comment:mint|comment:homomint - figure legend:3b|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/04/04 2020/08/14 rogid:2v7q3/Hu+V0aAylAQ6VMVMHeS6c9606 rogid:SOr81TwyfludaXvnbnQNtIIBpQM9606 rigid:Q/JRZNAgZpLQ+G+gLHh30JkmbFY false ha tag:?-? green fluorescent protein tag:?-? - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:Q8WY22 uniprotkb:O95415 intact:EBI-359348|uniprotkb:Q8WY23|ensembl:ENSP00000340761|ensembl:ENSP00000500359 intact:EBI-2874789|ensembl:ENSP00000297290|uniprotkb:Q8WV52|uniprotkb:Q9UIC6|uniprotkb:D6W5R8|intact:EBI-25504307|uniprotkb:F5GXW6|intact:EBI-25591918 psi-mi:bri3b_human(display_long)|uniprotkb:BRI3BP(gene name)|psi-mi:BRI3BP(display_short)|uniprotkb:KG19(gene name synonym)|uniprotkb:Cervical cancer 1 proto-oncogene-binding protein KG19(gene name synonym)|uniprotkb:HCCRBP-1(gene name synonym) psi-mi:bri3_human(display_long)|uniprotkb:BRI3(gene name)|psi-mi:BRI3(display_short)|uniprotkb:pRGR2(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Akiva et al. (2017) pubmed:30983867|imex:IM-27875 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-25504556|imex:IM-27875-23 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_542193.3|ensembl:ENSG00000184992(gene)|ensembl:ENST00000341446(transcript)|ensembl:ENST00000672415(transcript)|go:"GO:0005739"(mitochondrion)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0016021"(integral component of membrane)|interpro:IPR033367 ensembl:ENSG00000164713(gene)|ensembl:ENST00000297290(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005886"(plasma membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0035577"(azurophil granule membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|interpro:IPR019317|reactome:R-HSA-6798695|ensembl:ENSP00000297290|ensembl:ENST00000539286|ensembl:ENSP00000440936|refseq:NP_056194.1|refseq:NP_001152963.1 - - - figure legend:3b|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/04/04 2020/08/14 rogid:O9epHcfM1m7xNvrm6ELo0fRRGV49606 rogid:SOr81TwyfludaXvnbnQNtIIBpQM9606 rigid:uW0HebLCiYr0hdPh3nX9UGyjws4 false ha tag:?-? green fluorescent protein tag:?-? - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:Q01628 uniprotkb:O95415 intact:EBI-7932862|uniprotkb:Q96HK8|uniprotkb:Q53Y76|uniprotkb:Q96J15|intact:MINT-2805186|ensembl:ENSP00000382707 intact:EBI-2874789|ensembl:ENSP00000297290|uniprotkb:Q8WV52|uniprotkb:Q9UIC6|uniprotkb:D6W5R8|intact:EBI-25504307|uniprotkb:F5GXW6|intact:EBI-25591918 psi-mi:ifm3_human(display_long)|uniprotkb:IFITM3(gene name)|psi-mi:IFITM3(display_short)|uniprotkb:Dispanin subfamily A member 2b(gene name synonym)|uniprotkb:Interferon-inducible protein 1-8U(gene name synonym) psi-mi:bri3_human(display_long)|uniprotkb:BRI3(gene name)|psi-mi:BRI3(display_short)|uniprotkb:pRGR2(gene name synonym) psi-mi:"MI:0663"(confocal microscopy) Akiva et al. (2017) pubmed:30983867|imex:IM-27875 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0403"(colocalization) psi-mi:"MI:0469"(IntAct) intact:EBI-25504658|imex:IM-27875-13 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_066362.2|ensembl:ENSG00000142089(gene)|ensembl:ENST00000399808(transcript)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005886"(plasma membrane)|go:"GO:0006955"(immune response)|go:"GO:0016021"(integral component of membrane)|go:"GO:0031901"(early endosome membrane)|go:"GO:0031902"(late endosome membrane)|go:"GO:0032897"(negative regulation of viral transcription)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034341"(response to interferon-gamma)|go:"GO:0035455"(response to interferon-alpha)|go:"GO:0035456"(response to interferon-beta)|go:"GO:0045071"(negative regulation of viral genome replication)|go:"GO:0046597"(negative regulation of viral entry into host cell)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051607"(defense response to virus)|go:"GO:0060337"(type I interferon signaling pathway)|interpro:IPR007593(Interferon-induced transmembrane protein)|mint:Q01628|reactome:R-HSA-909733|go:"GO:0009615"(response to virus) ensembl:ENSG00000164713(gene)|ensembl:ENST00000297290(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005886"(plasma membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0035577"(azurophil granule membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|interpro:IPR019317|reactome:R-HSA-6798695|ensembl:ENSP00000297290|ensembl:ENST00000539286|ensembl:ENSP00000440936|refseq:NP_056194.1|refseq:NP_001152963.1 - comment:mint|comment:The tag used for detection by confocal microscopy is a DsRed fusion protein. - figure legend:4a|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-huh7)|taxid:9606(Homo sapiens hepatoma cell line established from a hepatocellular carcinoma) - 2020/04/04 2020/06/19 rogid:jR3B3HZZPwQAA1ccX0QeKYqa2449606 rogid:SOr81TwyfludaXvnbnQNtIIBpQM9606 rigid:0CFYz38Sv9+ZaJm6/In3KDb4WIA false red fluorescent protein tag:?-? green fluorescent protein tag:?-? - - psi-mi:"MI:0867"(tag visualisation by fluorescence) psi-mi:"MI:0867"(tag visualisation by fluorescence) uniprotkb:P26572 uniprotkb:O95415 intact:EBI-7211952|uniprotkb:B3KRU8|intact:MINT-4902561|uniprotkb:A8K404|intact:MINT-1196185|uniprotkb:Q6IBE3|uniprotkb:D3DWR1|intact:EBI-7263344|ensembl:ENSP00000311888|ensembl:ENSP00000332073|ensembl:ENSP00000377010|ensembl:ENSP00000402838|ensembl:ENSP00000404718 intact:EBI-2874789|ensembl:ENSP00000297290|uniprotkb:Q8WV52|uniprotkb:Q9UIC6|uniprotkb:D6W5R8|intact:EBI-25504307|uniprotkb:F5GXW6|intact:EBI-25591918 psi-mi:mgat1_human(display_long)|uniprotkb:MGAT1(gene name)|psi-mi:MGAT1(display_short)|uniprotkb:GGNT1(gene name synonym)|uniprotkb:GLCT1(gene name synonym)|uniprotkb:MGAT(gene name synonym)|uniprotkb:GLYT1(gene name synonym)|uniprotkb:N-glycosyl-oligosaccharide-glycoprotein N-acetylglucosaminyltransferase I(gene name synonym) psi-mi:bri3_human(display_long)|uniprotkb:BRI3(gene name)|psi-mi:BRI3(display_short)|uniprotkb:pRGR2(gene name synonym) psi-mi:"MI:0663"(confocal microscopy) Akiva et al. (2017) pubmed:30983867|imex:IM-27875 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0403"(colocalization) psi-mi:"MI:0469"(IntAct) intact:EBI-25504663|imex:IM-27875-15 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:XP_011532861.1|refseq:XP_011532862.1|refseq:XP_011532863.1|refseq:XP_011532864.1|refseq:XP_011532865.1|refseq:XP_005265972.1|refseq:XP_005265973.1|refseq:NP_001108090.1|refseq:NP_001108089.1|refseq:NP_001108091.1|refseq:NP_001108092.1|refseq:NP_002397.2|ensembl:ENSG00000131446(gene)|ensembl:ENST00000307826(transcript)|ensembl:ENST00000333055(transcript)|ensembl:ENST00000393340(transcript)|ensembl:ENST00000427865(transcript)|ensembl:ENST00000446023(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0003827"(alpha-1,3-mannosylglycoprotein 2-beta-N-acetylglucosaminyltransferase activity)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0006049"(UDP-N-acetylglucosamine catabolic process)|go:"GO:0006486"(protein glycosylation)|go:"GO:0006487"(protein N-linked glycosylation)|go:"GO:0008375"(acetylglucosaminyltransferase activity)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0018279"(protein N-linked glycosylation via asparagine)|go:"GO:0019082"(viral protein processing)|go:"GO:0030145"(manganese ion binding)|go:"GO:0033116"(endoplasmic reticulum-Golgi intermediate compartment membrane)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0070062"(extracellular exosome)|go:"GO:1903561"(extracellular vesicle)|interpro:IPR004139(Glycosyl transferase, family 13)|interpro:IPR029044|reactome:R-HSA-964739|reactome:R-HSA-9683686|reactome:R-HSA-9694548|refseq:XP_016864975.1|refseq:XP_016864976.1|refseq:XP_006714929.1 ensembl:ENSG00000164713(gene)|ensembl:ENST00000297290(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005886"(plasma membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0035577"(azurophil granule membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|interpro:IPR019317|reactome:R-HSA-6798695|ensembl:ENSP00000297290|ensembl:ENST00000539286|ensembl:ENSP00000440936|refseq:NP_056194.1|refseq:NP_001152963.1 - function:Initiates complex N-linked carbohydrate formation. Essential for the conversion of high-mannose to hybrid and complex N-glycans|comment:mint|comment:homomint - figure legend:4a|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-huh7)|taxid:9606(Homo sapiens hepatoma cell line established from a hepatocellular carcinoma) - 2020/04/04 2020/06/19 rogid:2v7q3/Hu+V0aAylAQ6VMVMHeS6c9606 rogid:SOr81TwyfludaXvnbnQNtIIBpQM9606 rigid:Q/JRZNAgZpLQ+G+gLHh30JkmbFY false red fluorescent protein tag:?-? green fluorescent protein tag:?-? - - psi-mi:"MI:0867"(tag visualisation by fluorescence) psi-mi:"MI:0867"(tag visualisation by fluorescence) uniprotkb:P26572 uniprotkb:O95415 intact:EBI-7211952|uniprotkb:B3KRU8|intact:MINT-4902561|uniprotkb:A8K404|intact:MINT-1196185|uniprotkb:Q6IBE3|uniprotkb:D3DWR1|intact:EBI-7263344|ensembl:ENSP00000311888|ensembl:ENSP00000332073|ensembl:ENSP00000377010|ensembl:ENSP00000402838|ensembl:ENSP00000404718 intact:EBI-2874789|ensembl:ENSP00000297290|uniprotkb:Q8WV52|uniprotkb:Q9UIC6|uniprotkb:D6W5R8|intact:EBI-25504307|uniprotkb:F5GXW6|intact:EBI-25591918 psi-mi:mgat1_human(display_long)|uniprotkb:MGAT1(gene name)|psi-mi:MGAT1(display_short)|uniprotkb:GGNT1(gene name synonym)|uniprotkb:GLCT1(gene name synonym)|uniprotkb:MGAT(gene name synonym)|uniprotkb:GLYT1(gene name synonym)|uniprotkb:N-glycosyl-oligosaccharide-glycoprotein N-acetylglucosaminyltransferase I(gene name synonym) psi-mi:bri3_human(display_long)|uniprotkb:BRI3(gene name)|psi-mi:BRI3(display_short)|uniprotkb:pRGR2(gene name synonym) psi-mi:"MI:0663"(confocal microscopy) Akiva et al. (2017) pubmed:30983867|imex:IM-27875 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0403"(colocalization) psi-mi:"MI:0469"(IntAct) intact:EBI-25504898|imex:IM-27875-17 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:XP_011532861.1|refseq:XP_011532862.1|refseq:XP_011532863.1|refseq:XP_011532864.1|refseq:XP_011532865.1|refseq:XP_005265972.1|refseq:XP_005265973.1|refseq:NP_001108090.1|refseq:NP_001108089.1|refseq:NP_001108091.1|refseq:NP_001108092.1|refseq:NP_002397.2|ensembl:ENSG00000131446(gene)|ensembl:ENST00000307826(transcript)|ensembl:ENST00000333055(transcript)|ensembl:ENST00000393340(transcript)|ensembl:ENST00000427865(transcript)|ensembl:ENST00000446023(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0003827"(alpha-1,3-mannosylglycoprotein 2-beta-N-acetylglucosaminyltransferase activity)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0006049"(UDP-N-acetylglucosamine catabolic process)|go:"GO:0006486"(protein glycosylation)|go:"GO:0006487"(protein N-linked glycosylation)|go:"GO:0008375"(acetylglucosaminyltransferase activity)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0018279"(protein N-linked glycosylation via asparagine)|go:"GO:0019082"(viral protein processing)|go:"GO:0030145"(manganese ion binding)|go:"GO:0033116"(endoplasmic reticulum-Golgi intermediate compartment membrane)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0070062"(extracellular exosome)|go:"GO:1903561"(extracellular vesicle)|interpro:IPR004139(Glycosyl transferase, family 13)|interpro:IPR029044|reactome:R-HSA-964739|reactome:R-HSA-9683686|reactome:R-HSA-9694548|refseq:XP_016864975.1|refseq:XP_016864976.1|refseq:XP_006714929.1 ensembl:ENSG00000164713(gene)|ensembl:ENST00000297290(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005886"(plasma membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0035577"(azurophil granule membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|interpro:IPR019317|reactome:R-HSA-6798695|ensembl:ENSP00000297290|ensembl:ENST00000539286|ensembl:ENSP00000440936|refseq:NP_056194.1|refseq:NP_001152963.1 - function:Initiates complex N-linked carbohydrate formation. Essential for the conversion of high-mannose to hybrid and complex N-glycans|comment:mint|comment:homomint - figure legend:4b|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-huh7)|taxid:9606(Homo sapiens hepatoma cell line established from a hepatocellular carcinoma) - 2020/04/04 2020/08/14 rogid:2v7q3/Hu+V0aAylAQ6VMVMHeS6c9606 rogid:SOr81TwyfludaXvnbnQNtIIBpQM9606 rigid:Q/JRZNAgZpLQ+G+gLHh30JkmbFY false red fluorescent protein tag:?-? green fluorescent protein tag:?-? - - psi-mi:"MI:0867"(tag visualisation by fluorescence) psi-mi:"MI:0867"(tag visualisation by fluorescence) uniprotkb:Q01628 uniprotkb:O95415 intact:EBI-7932862|uniprotkb:Q96HK8|uniprotkb:Q53Y76|uniprotkb:Q96J15|intact:MINT-2805186|ensembl:ENSP00000382707 intact:EBI-2874789|ensembl:ENSP00000297290|uniprotkb:Q8WV52|uniprotkb:Q9UIC6|uniprotkb:D6W5R8|intact:EBI-25504307|uniprotkb:F5GXW6|intact:EBI-25591918 psi-mi:ifm3_human(display_long)|uniprotkb:IFITM3(gene name)|psi-mi:IFITM3(display_short)|uniprotkb:Dispanin subfamily A member 2b(gene name synonym)|uniprotkb:Interferon-inducible protein 1-8U(gene name synonym) psi-mi:bri3_human(display_long)|uniprotkb:BRI3(gene name)|psi-mi:BRI3(display_short)|uniprotkb:pRGR2(gene name synonym) psi-mi:"MI:0663"(confocal microscopy) Akiva et al. (2017) pubmed:30983867|imex:IM-27875 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0403"(colocalization) psi-mi:"MI:0469"(IntAct) intact:EBI-25504929|imex:IM-27875-19 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_066362.2|ensembl:ENSG00000142089(gene)|ensembl:ENST00000399808(transcript)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005886"(plasma membrane)|go:"GO:0006955"(immune response)|go:"GO:0016021"(integral component of membrane)|go:"GO:0031901"(early endosome membrane)|go:"GO:0031902"(late endosome membrane)|go:"GO:0032897"(negative regulation of viral transcription)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034341"(response to interferon-gamma)|go:"GO:0035455"(response to interferon-alpha)|go:"GO:0035456"(response to interferon-beta)|go:"GO:0045071"(negative regulation of viral genome replication)|go:"GO:0046597"(negative regulation of viral entry into host cell)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051607"(defense response to virus)|go:"GO:0060337"(type I interferon signaling pathway)|interpro:IPR007593(Interferon-induced transmembrane protein)|mint:Q01628|reactome:R-HSA-909733|go:"GO:0009615"(response to virus) ensembl:ENSG00000164713(gene)|ensembl:ENST00000297290(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005886"(plasma membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0035577"(azurophil granule membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|interpro:IPR019317|reactome:R-HSA-6798695|ensembl:ENSP00000297290|ensembl:ENST00000539286|ensembl:ENSP00000440936|refseq:NP_056194.1|refseq:NP_001152963.1 - comment:mint - figure legend:4b|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-huh7)|taxid:9606(Homo sapiens hepatoma cell line established from a hepatocellular carcinoma) - 2020/04/04 2020/08/14 rogid:jR3B3HZZPwQAA1ccX0QeKYqa2449606 rogid:SOr81TwyfludaXvnbnQNtIIBpQM9606 rigid:0CFYz38Sv9+ZaJm6/In3KDb4WIA false red fluorescent protein tag:?-? green fluorescent protein tag:?-? - - psi-mi:"MI:0867"(tag visualisation by fluorescence) psi-mi:"MI:0867"(tag visualisation by fluorescence)