#ID(s) interactor A	ID(s) interactor B	Alt. ID(s) interactor A	Alt. ID(s) interactor B	Alias(es) interactor A	Alias(es) interactor B	Interaction detection method(s)	Publication 1st author(s)	Publication Identifier(s)	Taxid interactor A	Taxid interactor B	Interaction type(s)	Source database(s)	Interaction identifier(s)	Confidence value(s)	Expansion method(s)	Biological role(s) interactor A	Biological role(s) interactor B	Experimental role(s) interactor A	Experimental role(s) interactor B	Type(s) interactor A	Type(s) interactor B	Xref(s) interactor A	Xref(s) interactor B	Interaction Xref(s)	Annotation(s) interactor A	Annotation(s) interactor B	Interaction annotation(s)	Host organism(s)	Interaction parameter(s)	Creation date	Update date	Checksum(s) interactor A	Checksum(s) interactor B	Interaction Checksum(s)	Negative	Feature(s) interactor A	Feature(s) interactor B	Stoichiometry(s) interactor A	Stoichiometry(s) interactor B	Identification method participant A	Identification method participant B
uniprotkb:P9WMK3	uniprotkb:P71814	intact:EBI-26358664|uniprotkb:L0TC50|uniprotkb:O05824|uniprotkb:P64398	intact:EBI-26358631|uniprotkb:F2GMY3|uniprotkb:I6XW88	psi-mi:hrca_myctu(display_long)|uniprotkb:hrcA(gene name)|psi-mi:hrcA(display_short)|uniprotkb:MTCY27.06(orf name)|uniprotkb:Rv2374c(locus name)	psi-mi:p71814_myctu(display_long)|uniprotkb:phoP(gene name)|psi-mi:phoP(display_short)|uniprotkb:Rv0757(locus name)	psi-mi:"MI:0096"(pull down)	Sevalkar et al. (2019)	pubmed:30962357|imex:IM-28374	taxid:83332(myctu)|taxid:83332("Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)")	taxid:83332(myctu)|taxid:83332("Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)")	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26358684|imex:IM-28374-1	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	go:"GO:0003677"(DNA binding)|go:"GO:0005886"(plasma membrane)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|refseq:NP_216890.1|refseq:WP_003412252.1|interpro:IPR029016|interpro:IPR002571(Negative regulator of class I heat shock protein)|interpro:IPR021153|interpro:IPR036388|interpro:IPR036390|interpro:IPR023120	go:"GO:0000156"(phosphorelay response regulator activity)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0001216"(DNA-binding transcription activator activity)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006979"(response to oxidative stress)|go:"GO:0009247"(glycolipid biosynthetic process)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0032993"(protein-DNA complex)|go:"GO:0044315"(protein secretion by the type VII secretion system)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0046872"(metal ion binding)|go:"GO:0046889"(positive regulation of lipid biosynthetic process)|refseq:NP_215271.1|refseq:WP_003403867.1|rcsb pdb:3R0J|rcsb pdb:5ED4|interpro:IPR011006(CheY-like)|interpro:IPR001867(Signal transduction response regulator, C-terminal)|interpro:IPR016032(Signal transduction response regulator, C-terminal effector)|interpro:IPR001789(Signal transduction response regulator, receiver region)|interpro:IPR039420|interpro:IPR036388	-	-	-	figure legend:f3f|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2020/09/25	2020/10/13	rogid:hp4cWZvaDGyGpTB1cJQgaDzplCY83332	rogid:yBxJhHaeMd1s4MwJjuJ0ISIHqMQ83332	rigid:wljDv3VZN+B73Vgo34jOuAUvmxs	false	his tag:?-?	glutathione s tranferase tag:n-n	-	-	psi-mi:"MI:0705"(anti tag western blot)	psi-mi:"MI:0705"(anti tag western blot)
uniprotkb:P71814	uniprotkb:O06302	intact:EBI-26358631|uniprotkb:F2GMY3|uniprotkb:I6XW88	intact:EBI-6419119|uniprotkb:I6XV28|uniprotkb:F2GN43|uniprotkb:Q7D9Y9	psi-mi:p71814_myctu(display_long)|uniprotkb:phoP(gene name)|psi-mi:phoP(display_short)|uniprotkb:Rv0757(locus name)	psi-mi:o06302_myctu(display_long)|uniprotkb:hspR(gene name)|psi-mi:hspR(display_short)|uniprotkb:Rv0353(locus name)	psi-mi:"MI:0096"(pull down)	Sevalkar et al. (2019)	pubmed:30962357|imex:IM-28374	taxid:83332(myctu)|taxid:83332("Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)")	taxid:83332(myctu)|taxid:83332("Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)")	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26358758|imex:IM-28374-5	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	go:"GO:0000156"(phosphorelay response regulator activity)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0001216"(DNA-binding transcription activator activity)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006979"(response to oxidative stress)|go:"GO:0009247"(glycolipid biosynthetic process)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0032993"(protein-DNA complex)|go:"GO:0044315"(protein secretion by the type VII secretion system)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0046872"(metal ion binding)|go:"GO:0046889"(positive regulation of lipid biosynthetic process)|refseq:NP_215271.1|refseq:WP_003403867.1|rcsb pdb:3R0J|rcsb pdb:5ED4|interpro:IPR011006(CheY-like)|interpro:IPR001867(Signal transduction response regulator, C-terminal)|interpro:IPR016032(Signal transduction response regulator, C-terminal effector)|interpro:IPR001789(Signal transduction response regulator, receiver region)|interpro:IPR039420|interpro:IPR036388	go:"GO:0000984"|go:"GO:0005886"(plasma membrane)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|interpro:IPR000551(Bacterial regulatory protein, MerR)|interpro:IPR009061(Putative DNA binding)|refseq:NP_214867.1|refseq:WP_003401823.1	-	-	-	figure legend:f4b|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2020/09/25	2020/10/13	rogid:yBxJhHaeMd1s4MwJjuJ0ISIHqMQ83332	rogid:C8FWHeMm6z97hoPMt86gk1uMNOg83332	rigid:7KDuLAfQ5+dmy9QeTC61W0Y322U	false	glutathione s tranferase tag:?-?	his tag:?-?|necessary binding region:117-126	-	-	psi-mi:"MI:0705"(anti tag western blot)	psi-mi:"MI:0705"(anti tag western blot)
uniprotkb:P71814	uniprotkb:O06302	intact:EBI-26358631|uniprotkb:F2GMY3|uniprotkb:I6XW88	intact:EBI-6419119|uniprotkb:I6XV28|uniprotkb:F2GN43|uniprotkb:Q7D9Y9	psi-mi:p71814_myctu(display_long)|uniprotkb:phoP(gene name)|psi-mi:phoP(display_short)|uniprotkb:Rv0757(locus name)	psi-mi:o06302_myctu(display_long)|uniprotkb:hspR(gene name)|psi-mi:hspR(display_short)|uniprotkb:Rv0353(locus name)	psi-mi:"MI:0096"(pull down)	Sevalkar et al. (2019)	pubmed:30962357|imex:IM-28374	taxid:83332(myctu)|taxid:83332("Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)")	taxid:83332(myctu)|taxid:83332("Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)")	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26358778|imex:IM-28374-7	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	go:"GO:0000156"(phosphorelay response regulator activity)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0001216"(DNA-binding transcription activator activity)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006979"(response to oxidative stress)|go:"GO:0009247"(glycolipid biosynthetic process)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0032993"(protein-DNA complex)|go:"GO:0044315"(protein secretion by the type VII secretion system)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0046872"(metal ion binding)|go:"GO:0046889"(positive regulation of lipid biosynthetic process)|refseq:NP_215271.1|refseq:WP_003403867.1|rcsb pdb:3R0J|rcsb pdb:5ED4|interpro:IPR011006(CheY-like)|interpro:IPR001867(Signal transduction response regulator, C-terminal)|interpro:IPR016032(Signal transduction response regulator, C-terminal effector)|interpro:IPR001789(Signal transduction response regulator, receiver region)|interpro:IPR039420|interpro:IPR036388	go:"GO:0000984"|go:"GO:0005886"(plasma membrane)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|interpro:IPR000551(Bacterial regulatory protein, MerR)|interpro:IPR009061(Putative DNA binding)|refseq:NP_214867.1|refseq:WP_003401823.1	-	-	-	figure legend:f4c|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2020/09/25	2020/10/07	rogid:yBxJhHaeMd1s4MwJjuJ0ISIHqMQ83332	rogid:C8FWHeMm6z97hoPMt86gk1uMNOg83332	rigid:7KDuLAfQ5+dmy9QeTC61W0Y322U	false	his tag:?-?|sufficient binding region:1-141	glutathione s tranferase tag:n-n	-	-	psi-mi:"MI:0705"(anti tag western blot)	psi-mi:"MI:0705"(anti tag western blot)
uniprotkb:P9WMK3	uniprotkb:P71814	intact:EBI-26358664|uniprotkb:L0TC50|uniprotkb:O05824|uniprotkb:P64398	intact:EBI-26358631|uniprotkb:F2GMY3|uniprotkb:I6XW88	psi-mi:hrca_myctu(display_long)|uniprotkb:hrcA(gene name)|psi-mi:hrcA(display_short)|uniprotkb:MTCY27.06(orf name)|uniprotkb:Rv2374c(locus name)	psi-mi:p71814_myctu(display_long)|uniprotkb:phoP(gene name)|psi-mi:phoP(display_short)|uniprotkb:Rv0757(locus name)	psi-mi:"MI:0096"(pull down)	Sevalkar et al. (2019)	pubmed:30962357|imex:IM-28374	taxid:83332(myctu)|taxid:83332("Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)")	taxid:83332(myctu)|taxid:83332("Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)")	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26358790|imex:IM-28374-9	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	go:"GO:0003677"(DNA binding)|go:"GO:0005886"(plasma membrane)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|refseq:NP_216890.1|refseq:WP_003412252.1|interpro:IPR029016|interpro:IPR002571(Negative regulator of class I heat shock protein)|interpro:IPR021153|interpro:IPR036388|interpro:IPR036390|interpro:IPR023120	go:"GO:0000156"(phosphorelay response regulator activity)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0001216"(DNA-binding transcription activator activity)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006979"(response to oxidative stress)|go:"GO:0009247"(glycolipid biosynthetic process)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0032993"(protein-DNA complex)|go:"GO:0044315"(protein secretion by the type VII secretion system)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0046872"(metal ion binding)|go:"GO:0046889"(positive regulation of lipid biosynthetic process)|refseq:NP_215271.1|refseq:WP_003403867.1|rcsb pdb:3R0J|rcsb pdb:5ED4|interpro:IPR011006(CheY-like)|interpro:IPR001867(Signal transduction response regulator, C-terminal)|interpro:IPR016032(Signal transduction response regulator, C-terminal effector)|interpro:IPR001789(Signal transduction response regulator, receiver region)|interpro:IPR039420|interpro:IPR036388	-	-	-	figure legend:f5b|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2020/09/25	2020/10/07	rogid:hp4cWZvaDGyGpTB1cJQgaDzplCY83332	rogid:yBxJhHaeMd1s4MwJjuJ0ISIHqMQ83332	rigid:wljDv3VZN+B73Vgo34jOuAUvmxs	false	his tag:?-?|necessary binding region:326-343	glutathione s tranferase tag:n-n	-	-	psi-mi:"MI:0705"(anti tag western blot)	psi-mi:"MI:0705"(anti tag western blot)
uniprotkb:P9WMK3	uniprotkb:P71814	intact:EBI-26358664|uniprotkb:L0TC50|uniprotkb:O05824|uniprotkb:P64398	intact:EBI-26358631|uniprotkb:F2GMY3|uniprotkb:I6XW88	psi-mi:hrca_myctu(display_long)|uniprotkb:hrcA(gene name)|psi-mi:hrcA(display_short)|uniprotkb:MTCY27.06(orf name)|uniprotkb:Rv2374c(locus name)	psi-mi:p71814_myctu(display_long)|uniprotkb:phoP(gene name)|psi-mi:phoP(display_short)|uniprotkb:Rv0757(locus name)	psi-mi:"MI:0096"(pull down)	Sevalkar et al. (2019)	pubmed:30962357|imex:IM-28374	taxid:83332(myctu)|taxid:83332("Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)")	taxid:83332(myctu)|taxid:83332("Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)")	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26358800|imex:IM-28374-11	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	go:"GO:0003677"(DNA binding)|go:"GO:0005886"(plasma membrane)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|refseq:NP_216890.1|refseq:WP_003412252.1|interpro:IPR029016|interpro:IPR002571(Negative regulator of class I heat shock protein)|interpro:IPR021153|interpro:IPR036388|interpro:IPR036390|interpro:IPR023120	go:"GO:0000156"(phosphorelay response regulator activity)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0001216"(DNA-binding transcription activator activity)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006979"(response to oxidative stress)|go:"GO:0009247"(glycolipid biosynthetic process)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0032993"(protein-DNA complex)|go:"GO:0044315"(protein secretion by the type VII secretion system)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0046872"(metal ion binding)|go:"GO:0046889"(positive regulation of lipid biosynthetic process)|refseq:NP_215271.1|refseq:WP_003403867.1|rcsb pdb:3R0J|rcsb pdb:5ED4|interpro:IPR011006(CheY-like)|interpro:IPR001867(Signal transduction response regulator, C-terminal)|interpro:IPR016032(Signal transduction response regulator, C-terminal effector)|interpro:IPR001789(Signal transduction response regulator, receiver region)|interpro:IPR039420|interpro:IPR036388	-	-	-	figure legend:f5e|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2020/09/25	2020/10/13	rogid:hp4cWZvaDGyGpTB1cJQgaDzplCY83332	rogid:yBxJhHaeMd1s4MwJjuJ0ISIHqMQ83332	rigid:wljDv3VZN+B73Vgo34jOuAUvmxs	false	glutathione s tranferase tag:n-n	his tag:?-?|sufficient binding region:1-141	-	-	psi-mi:"MI:0705"(anti tag western blot)	psi-mi:"MI:0705"(anti tag western blot)
uniprotkb:P71814	uniprotkb:O06302	intact:EBI-26358631|uniprotkb:F2GMY3|uniprotkb:I6XW88	intact:EBI-6419119|uniprotkb:I6XV28|uniprotkb:F2GN43|uniprotkb:Q7D9Y9	psi-mi:p71814_myctu(display_long)|uniprotkb:phoP(gene name)|psi-mi:phoP(display_short)|uniprotkb:Rv0757(locus name)	psi-mi:o06302_myctu(display_long)|uniprotkb:hspR(gene name)|psi-mi:hspR(display_short)|uniprotkb:Rv0353(locus name)	psi-mi:"MI:0096"(pull down)	Sevalkar et al. (2019)	pubmed:30962357|imex:IM-28374	taxid:83332(myctu)|taxid:83332("Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)")	taxid:83332(myctu)|taxid:83332("Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)")	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26358811|imex:IM-28374-13	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	go:"GO:0000156"(phosphorelay response regulator activity)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0001216"(DNA-binding transcription activator activity)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006979"(response to oxidative stress)|go:"GO:0009247"(glycolipid biosynthetic process)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0032993"(protein-DNA complex)|go:"GO:0044315"(protein secretion by the type VII secretion system)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0046872"(metal ion binding)|go:"GO:0046889"(positive regulation of lipid biosynthetic process)|refseq:NP_215271.1|refseq:WP_003403867.1|rcsb pdb:3R0J|rcsb pdb:5ED4|interpro:IPR011006(CheY-like)|interpro:IPR001867(Signal transduction response regulator, C-terminal)|interpro:IPR016032(Signal transduction response regulator, C-terminal effector)|interpro:IPR001789(Signal transduction response regulator, receiver region)|interpro:IPR039420|interpro:IPR036388	go:"GO:0000984"|go:"GO:0005886"(plasma membrane)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|interpro:IPR000551(Bacterial regulatory protein, MerR)|interpro:IPR009061(Putative DNA binding)|refseq:NP_214867.1|refseq:WP_003401823.1	-	-	-	figure legend:sf7a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2020/09/25	2020/10/13	rogid:yBxJhHaeMd1s4MwJjuJ0ISIHqMQ83332	rogid:C8FWHeMm6z97hoPMt86gk1uMNOg83332	rigid:7KDuLAfQ5+dmy9QeTC61W0Y322U	false	his tag:n-n|mutation with no effect:27-29|mutation with no effect:31-33|mutation with no effect:80-82|mutation with no effect:103-105	glutathione s tranferase tag:n-n	-	-	psi-mi:"MI:0705"(anti tag western blot)	psi-mi:"MI:0705"(anti tag western blot)
uniprotkb:P9WMK3	uniprotkb:P71814	intact:EBI-26358664|uniprotkb:L0TC50|uniprotkb:O05824|uniprotkb:P64398	intact:EBI-26358631|uniprotkb:F2GMY3|uniprotkb:I6XW88	psi-mi:hrca_myctu(display_long)|uniprotkb:hrcA(gene name)|psi-mi:hrcA(display_short)|uniprotkb:MTCY27.06(orf name)|uniprotkb:Rv2374c(locus name)	psi-mi:p71814_myctu(display_long)|uniprotkb:phoP(gene name)|psi-mi:phoP(display_short)|uniprotkb:Rv0757(locus name)	psi-mi:"MI:0096"(pull down)	Sevalkar et al. (2019)	pubmed:30962357|imex:IM-28374	taxid:83332(myctu)|taxid:83332("Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)")	taxid:83332(myctu)|taxid:83332("Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)")	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26358713|imex:IM-28374-3	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	go:"GO:0003677"(DNA binding)|go:"GO:0005886"(plasma membrane)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|refseq:NP_216890.1|refseq:WP_003412252.1|interpro:IPR029016|interpro:IPR002571(Negative regulator of class I heat shock protein)|interpro:IPR021153|interpro:IPR036388|interpro:IPR036390|interpro:IPR023120	go:"GO:0000156"(phosphorelay response regulator activity)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0001216"(DNA-binding transcription activator activity)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006979"(response to oxidative stress)|go:"GO:0009247"(glycolipid biosynthetic process)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0032993"(protein-DNA complex)|go:"GO:0044315"(protein secretion by the type VII secretion system)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0046872"(metal ion binding)|go:"GO:0046889"(positive regulation of lipid biosynthetic process)|refseq:NP_215271.1|refseq:WP_003403867.1|rcsb pdb:3R0J|rcsb pdb:5ED4|interpro:IPR011006(CheY-like)|interpro:IPR001867(Signal transduction response regulator, C-terminal)|interpro:IPR016032(Signal transduction response regulator, C-terminal effector)|interpro:IPR001789(Signal transduction response regulator, receiver region)|interpro:IPR039420|interpro:IPR036388	-	-	-	figure legend:f3g|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:83331(mycto)|taxid:83331("Mycobacterium tuberculosis (strain CDC 1551 / Oshkosh)")	-	2020/09/25	2020/09/25	rogid:hp4cWZvaDGyGpTB1cJQgaDzplCY83332	rogid:yBxJhHaeMd1s4MwJjuJ0ISIHqMQ83332	rigid:wljDv3VZN+B73Vgo34jOuAUvmxs	false	-	his tag:?-?	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:P9WMK3	uniprotkb:P71814	intact:EBI-26358664|uniprotkb:L0TC50|uniprotkb:O05824|uniprotkb:P64398	intact:EBI-26358631|uniprotkb:F2GMY3|uniprotkb:I6XW88	psi-mi:hrca_myctu(display_long)|uniprotkb:hrcA(gene name)|psi-mi:hrcA(display_short)|uniprotkb:MTCY27.06(orf name)|uniprotkb:Rv2374c(locus name)	psi-mi:p71814_myctu(display_long)|uniprotkb:phoP(gene name)|psi-mi:phoP(display_short)|uniprotkb:Rv0757(locus name)	psi-mi:"MI:0111"(dihydrofolate reductase reconstruction)	Sevalkar et al. (2019)	pubmed:30962357|imex:IM-28374	taxid:83332(myctu)|taxid:83332("Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)")	taxid:83332(myctu)|taxid:83332("Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)")	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26365673|imex:IM-28374-14	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	go:"GO:0003677"(DNA binding)|go:"GO:0005886"(plasma membrane)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|refseq:NP_216890.1|refseq:WP_003412252.1|interpro:IPR029016|interpro:IPR002571(Negative regulator of class I heat shock protein)|interpro:IPR021153|interpro:IPR036388|interpro:IPR036390|interpro:IPR023120	go:"GO:0000156"(phosphorelay response regulator activity)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0001216"(DNA-binding transcription activator activity)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006979"(response to oxidative stress)|go:"GO:0009247"(glycolipid biosynthetic process)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0032993"(protein-DNA complex)|go:"GO:0044315"(protein secretion by the type VII secretion system)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0046872"(metal ion binding)|go:"GO:0046889"(positive regulation of lipid biosynthetic process)|refseq:NP_215271.1|refseq:WP_003403867.1|rcsb pdb:3R0J|rcsb pdb:5ED4|interpro:IPR011006(CheY-like)|interpro:IPR001867(Signal transduction response regulator, C-terminal)|interpro:IPR016032(Signal transduction response regulator, C-terminal effector)|interpro:IPR001789(Signal transduction response regulator, receiver region)|interpro:IPR039420|interpro:IPR036388	-	-	-	figure legend:f3h f5c f5f|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:1772(mycsm)|taxid:1772(Mycobacterium smegmatis)	-	2020/09/25	2020/10/07	rogid:hp4cWZvaDGyGpTB1cJQgaDzplCY83332	rogid:yBxJhHaeMd1s4MwJjuJ0ISIHqMQ83332	rigid:wljDv3VZN+B73Vgo34jOuAUvmxs	false	fusion protein:?-?|necessary binding region:326-343	necessary binding region:1-141|fusion protein:?-?	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P71814	uniprotkb:O06302	intact:EBI-26358631|uniprotkb:F2GMY3|uniprotkb:I6XW88	intact:EBI-6419119|uniprotkb:I6XV28|uniprotkb:F2GN43|uniprotkb:Q7D9Y9	psi-mi:p71814_myctu(display_long)|uniprotkb:phoP(gene name)|psi-mi:phoP(display_short)|uniprotkb:Rv0757(locus name)	psi-mi:o06302_myctu(display_long)|uniprotkb:hspR(gene name)|psi-mi:hspR(display_short)|uniprotkb:Rv0353(locus name)	psi-mi:"MI:0111"(dihydrofolate reductase reconstruction)	Sevalkar et al. (2019)	pubmed:30962357|imex:IM-28374	taxid:83332(myctu)|taxid:83332("Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)")	taxid:83332(myctu)|taxid:83332("Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)")	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26365689|imex:IM-28374-16	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	go:"GO:0000156"(phosphorelay response regulator activity)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0001216"(DNA-binding transcription activator activity)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006979"(response to oxidative stress)|go:"GO:0009247"(glycolipid biosynthetic process)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0032993"(protein-DNA complex)|go:"GO:0044315"(protein secretion by the type VII secretion system)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0046872"(metal ion binding)|go:"GO:0046889"(positive regulation of lipid biosynthetic process)|refseq:NP_215271.1|refseq:WP_003403867.1|rcsb pdb:3R0J|rcsb pdb:5ED4|interpro:IPR011006(CheY-like)|interpro:IPR001867(Signal transduction response regulator, C-terminal)|interpro:IPR016032(Signal transduction response regulator, C-terminal effector)|interpro:IPR001789(Signal transduction response regulator, receiver region)|interpro:IPR039420|interpro:IPR036388	go:"GO:0000984"|go:"GO:0005886"(plasma membrane)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|interpro:IPR000551(Bacterial regulatory protein, MerR)|interpro:IPR009061(Putative DNA binding)|refseq:NP_214867.1|refseq:WP_003401823.1	-	-	-	figure legend:sf7b|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:1772(mycsm)|taxid:1772(Mycobacterium smegmatis)	-	2020/09/25	2020/10/07	rogid:yBxJhHaeMd1s4MwJjuJ0ISIHqMQ83332	rogid:C8FWHeMm6z97hoPMt86gk1uMNOg83332	rigid:7KDuLAfQ5+dmy9QeTC61W0Y322U	false	necessary binding region:1-141|fusion protein:?-?	fusion protein:?-?	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P9WNK7	uniprotkb:P9WNK5	intact:EBI-1253925|uniprotkb:F2GDN6|uniprotkb:Q540D8|uniprotkb:O84901|uniprotkb:Q57165|uniprotkb:P0A564	intact:EBI-1253936|uniprotkb:O69739|uniprotkb:L0TDT9|uniprotkb:P0A566	psi-mi:esxa_myctu(display_long)|uniprotkb:esxA(gene name)|psi-mi:esxA(display_short)|uniprotkb:esaT6(gene name synonym)|uniprotkb:Rv3875(locus name)|uniprotkb:MTV027.10(orf name)|uniprotkb:ESAT-6(gene name synonym)	psi-mi:esxb_myctu(display_long)|uniprotkb:esxB(gene name)|psi-mi:esxB(display_short)|uniprotkb:cfp10(gene name synonym)|uniprotkb:lhp(gene name synonym)|uniprotkb:mtsA10(gene name synonym)|uniprotkb:Rv3874(locus name)|uniprotkb:MTV027.09(orf name)|uniprotkb:10 kDa culture filtrate antigen CFP-10(gene name synonym)|uniprotkb:Secreted antigenic protein MTSA-10(gene name synonym)	psi-mi:"MI:0111"(dihydrofolate reductase reconstruction)	Sevalkar et al. (2019)	pubmed:30962357|imex:IM-28374	taxid:83332(myctu)|taxid:83332("Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)")	taxid:83332(myctu)|taxid:83332("Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)")	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26365701|imex:IM-28374-18	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:YP_178023.1|refseq:WP_003399963.1|mint:P9WNK7|dip:DIP-61227N|go:"GO:0005576"(extracellular region)|go:"GO:0005618"(cell wall)|go:"GO:0005737"(cytoplasm)|go:"GO:0005788"(endoplasmic reticulum lumen)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0020002"(host cell plasma membrane)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0044165"(host cell endoplasmic reticulum)|go:"GO:0044228"(host cell surface)|go:"GO:0044315"(protein secretion by the type VII secretion system)|go:"GO:0046812"(host cell surface binding)|go:"GO:0052027"(modulation by symbiont of host signal transduction pathway)|go:"GO:0052083"(suppression by symbiont of host cell-mediated immune response)|go:"GO:0052085"(suppression by symbiont of host T-cell mediated immune response)|interpro:IPR010310(Protein of unknown function DUF909)|interpro:IPR036689|rcsb pdb:1WA8|rcsb pdb:3FAV|reactome:R-HSA-9636667|reactome:R-HSA-9637628	refseq:NP_218391.1|interpro:IPR010310(Protein of unknown function DUF909)|refseq:WP_003399940.1|mint:P9WNK5|interpro:IPR036689|go:"GO:0005576"(extracellular region)|go:"GO:0005618"(cell wall)|go:"GO:0005886"(plasma membrane)|go:"GO:0044165"(host cell endoplasmic reticulum)|go:"GO:0044228"(host cell surface)|go:"GO:0044315"(protein secretion by the type VII secretion system)|go:"GO:0046812"(host cell surface binding)|rcsb pdb:1WA8|rcsb pdb:3FAV|rcsb pdb:6J19	-	-	-	figure legend:f3h|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:1772(mycsm)|taxid:1772(Mycobacterium smegmatis)	-	2020/09/25	2020/10/07	rogid:ZHAEE5EVBqthtYz3uzNnohFtr3Q83332	rogid:vmB4BvNHEG7Jq9tk4PooRd2yYHE83332	rigid:Eem0dlTiZaTm9pLwnqA+/vpFA4s	false	fusion protein:?-?	fusion protein:?-?	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)