#ID(s) interactor A ID(s) interactor B Alt. ID(s) interactor A Alt. ID(s) interactor B Alias(es) interactor A Alias(es) interactor B Interaction detection method(s) Publication 1st author(s) Publication Identifier(s) Taxid interactor A Taxid interactor B Interaction type(s) Source database(s) Interaction identifier(s) Confidence value(s) Expansion method(s) Biological role(s) interactor A Biological role(s) interactor B Experimental role(s) interactor A Experimental role(s) interactor B Type(s) interactor A Type(s) interactor B Xref(s) interactor A Xref(s) interactor B Interaction Xref(s) Annotation(s) interactor A Annotation(s) interactor B Interaction annotation(s) Host organism(s) Interaction parameter(s) Creation date Update date Checksum(s) interactor A Checksum(s) interactor B Interaction Checksum(s) Negative Feature(s) interactor A Feature(s) interactor B Stoichiometry(s) interactor A Stoichiometry(s) interactor B Identification method participant A Identification method participant B uniprotkb:Q96RY7 uniprotkb:Q8NDW8 intact:EBI-308494|uniprotkb:O60332|uniprotkb:Q9UG52|uniprotkb:A2A2A8|uniprotkb:D3DU75|ensembl:ENSP00000406012 intact:EBI-11922704|ensembl:ENSP00000398211|uniprotkb:A1L388|uniprotkb:B4DYF6|uniprotkb:B4DYJ3|uniprotkb:D3YTE7|uniprotkb:D4PHA5|uniprotkb:Q6P5W8|uniprotkb:Q8N7G5|uniprotkb:Q8NA02 psi-mi:if140_human(display_long)|uniprotkb:IFT140(gene name)|psi-mi:IFT140(display_short)|uniprotkb:KIAA0590(gene name synonym)|uniprotkb:WDTC2(gene name synonym)|uniprotkb:WD and tetratricopeptide repeats protein 2(gene name synonym) psi-mi:tt21a_human(display_long)|uniprotkb:TTC21A(gene name)|psi-mi:TTC21A(display_short)|uniprotkb:STI2(gene name synonym)|uniprotkb:Stress-inducible protein 2(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Liu et al. (2019) imex:IM-27890|pubmed:30929735 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-25505814|imex:IM-27890-1 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_055529.2|ensembl:ENSG00000187535(gene)|ensembl:ENST00000426508(transcript)|go:"GO:0001750"(photoreceptor outer segment)|go:"GO:0005813"(centrosome)|go:"GO:0005814"(centriole)|go:"GO:0005929"(cilium)|go:"GO:0005930"(axoneme)|go:"GO:0007368"(determination of left/right symmetry)|go:"GO:0007507"(heart development)|go:"GO:0008589"(regulation of smoothened signaling pathway)|go:"GO:0021532"(neural tube patterning)|go:"GO:0030991"(intraciliary transport particle A)|go:"GO:0031076"(embryonic camera-type eye development)|go:"GO:0032391"(photoreceptor connecting cilium)|go:"GO:0035721"(intraciliary retrograde transport)|go:"GO:0035845"(photoreceptor cell outer segment organization)|go:"GO:0036064"(ciliary basal body)|go:"GO:0042073"(intraciliary transport)|go:"GO:0042733"(embryonic digit morphogenesis)|go:"GO:0048701"(embryonic cranial skeleton morphogenesis)|go:"GO:1990403"(embryonic brain development)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR036322|reactome:R-HSA-5610787|reactome:R-HSA-5620924|go:"GO:0060271"(cilium assembly)|go:"GO:0061512"(protein localization to cilium)|go:"GO:0097542"(ciliary tip)|go:"GO:1902017"(regulation of cilium assembly)|go:"GO:1905515"(non-motile cilium assembly)|refseq:XP_006721053.1|refseq:XP_006721054.1|refseq:XP_016879399.1 ensembl:ENSG00000168026(gene)|ensembl:ENST00000431162(transcript)|go:"GO:0005929"(cilium)|go:"GO:0007286"(spermatid development)|go:"GO:0030317"(flagellated sperm motility)|go:"GO:0030991"(intraciliary transport particle A)|go:"GO:0035721"(intraciliary retrograde transport)|go:"GO:0061512"(protein localization to cilium)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR019734|interpro:IPR040364|refseq:NP_001098983.2|refseq:NP_665698.2 - - - figure legend:"Figure S6 A. Co-Immunoprecipitation (Co-IP) Assays of Human Spermatozoa Revealed the Interactions between TTC21A and Known IFT Proteins."|sample process:Protein A agarose beads were used for enrichment of all the baits|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-sperm)|taxid:9606(Homo sapiens - sperm) - 2020/04/08 2020/04/08 rogid:LQ8zt35IhriM/UbIOoQXk72oLAQ9606 rogid:r4uyPCeaIaYrf4W4ozrfDXFIIdk9606 rigid:kaT5Ih9oUk7Ei57xeIHYN4CW3iA false - - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:Q8IY31 uniprotkb:Q8NDW8 intact:EBI-744203|uniprotkb:Q5GLZ2|uniprotkb:Q9BUG5|intact:EBI-2561300|uniprotkb:J3QL09|ensembl:ENSP00000378809|ensembl:ENSP00000463138 intact:EBI-11922704|ensembl:ENSP00000398211|uniprotkb:A1L388|uniprotkb:B4DYF6|uniprotkb:B4DYJ3|uniprotkb:D3YTE7|uniprotkb:D4PHA5|uniprotkb:Q6P5W8|uniprotkb:Q8N7G5|uniprotkb:Q8NA02 psi-mi:ift20_human(display_long)|uniprotkb:IFT20(gene name)|psi-mi:IFT20(display_short) psi-mi:tt21a_human(display_long)|uniprotkb:TTC21A(gene name)|psi-mi:TTC21A(display_short)|uniprotkb:STI2(gene name synonym)|uniprotkb:Stress-inducible protein 2(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Liu et al. (2019) imex:IM-27890|pubmed:30929735 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-25505844|imex:IM-27890-3 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001254706.1|refseq:NP_001254707.1|refseq:NP_777547.1|refseq:NP_001254703.1|refseq:NP_001254704.1|refseq:NP_001254705.1|ensembl:ENSG00000109083(gene)|ensembl:ENST00000395418(transcript)|ensembl:ENST00000585313(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001736"(establishment of planar polarity)|go:"GO:0001750"(photoreceptor outer segment)|go:"GO:0001822"(kidney development)|go:"GO:0002046"(opsin binding)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005801"(cis-Golgi network)|go:"GO:0005813"(centrosome)|go:"GO:0005814"(centriole)|go:"GO:0005902"(microvillus)|go:"GO:0005929"(cilium)|go:"GO:0007224"(smoothened signaling pathway)|go:"GO:0007283"(spermatogenesis)|go:"GO:0008542"(visual learning)|go:"GO:0030992"(intraciliary transport particle B)|go:"GO:0031267"(small GTPase binding)|go:"GO:0031514"(motile cilium)|go:"GO:0032391"(photoreceptor connecting cilium)|go:"GO:0032420"(stereocilium)|go:"GO:0034067"(protein localization to Golgi apparatus)|go:"GO:0035845"(photoreceptor cell outer segment organization)|go:"GO:0036372"(opsin transport)|go:"GO:0042073"(intraciliary transport)|go:"GO:0044292"(dendrite terminus)|go:"GO:0045198"(establishment of epithelial cell apical/basal polarity)|go:"GO:0051642"(centrosome localization)|go:"GO:0055007"(cardiac muscle cell differentiation)|go:"GO:0060122"(inner ear receptor cell stereocilium organization)|go:"GO:0060271"(cilium assembly)|go:"GO:0060828"(regulation of canonical Wnt signaling pathway)|go:"GO:0061351"(neural precursor cell proliferation)|go:"GO:0061512"(protein localization to cilium)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0090102"(cochlea development)|go:"GO:0097542"(ciliary tip)|go:"GO:0097546"(ciliary base)|go:"GO:1902017"(regulation of cilium assembly)|go:"GO:1902636"(kinociliary basal body)|go:"GO:2000583"(regulation of platelet-derived growth factor receptor-alpha signaling pathway)|go:"GO:2000785"(regulation of autophagosome assembly)|interpro:IPR028172|reactome:R-HSA-5620924 ensembl:ENSG00000168026(gene)|ensembl:ENST00000431162(transcript)|go:"GO:0005929"(cilium)|go:"GO:0007286"(spermatid development)|go:"GO:0030317"(flagellated sperm motility)|go:"GO:0030991"(intraciliary transport particle A)|go:"GO:0035721"(intraciliary retrograde transport)|go:"GO:0061512"(protein localization to cilium)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR019734|interpro:IPR040364|refseq:NP_001098983.2|refseq:NP_665698.2 - - - figure legend:"Figure S6 B. Co-Immunoprecipitation (Co-IP) Assays of Human Spermatozoa Revealed the Interactions between TTC21A and Known IFT Proteins."|sample process:Protein A agarose beads were used for enrichment of all the baits|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-sperm)|taxid:9606(Homo sapiens - sperm) - 2020/04/08 2020/04/08 rogid:/sGgagcq0b/YoxjD4Psc7D6jY2Q9606 rogid:r4uyPCeaIaYrf4W4ozrfDXFIIdk9606 rigid:rB52B4XfF1wH49m5Eu4zve+1U1g false - - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:Q9Y366 uniprotkb:Q8NDW8 intact:EBI-11927321|ensembl:ENSP00000362121|ensembl:ENSP00000362130|uniprotkb:B3KMA1|uniprotkb:E1P5W9|uniprotkb:Q5H8Z0|uniprotkb:Q9H1G3|uniprotkb:Q9H1G4|uniprotkb:Q9H1H2 intact:EBI-11922704|ensembl:ENSP00000398211|uniprotkb:A1L388|uniprotkb:B4DYF6|uniprotkb:B4DYJ3|uniprotkb:D3YTE7|uniprotkb:D4PHA5|uniprotkb:Q6P5W8|uniprotkb:Q8N7G5|uniprotkb:Q8NA02 psi-mi:ift52_human(display_long)|uniprotkb:IFT52(gene name)|psi-mi:IFT52(display_short)|uniprotkb:C20orf9(gene name synonym)|uniprotkb:NGD5(gene name synonym)|uniprotkb:Protein NGD5 homolog(gene name synonym)|uniprotkb:CGI-53(orf name) psi-mi:tt21a_human(display_long)|uniprotkb:TTC21A(gene name)|psi-mi:TTC21A(display_short)|uniprotkb:STI2(gene name synonym)|uniprotkb:Stress-inducible protein 2(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Liu et al. (2019) imex:IM-27890|pubmed:30929735 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-25505854|imex:IM-27890-5 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSP00000362121|ensembl:ENSP00000362130|ensembl:ENSG00000101052(gene)|ensembl:ENST00000373030(transcript)|ensembl:ENST00000373039(transcript)|go:"GO:0001841"(neural tube formation)|go:"GO:0001947"(heart looping)|go:"GO:0005813"(centrosome)|go:"GO:0005814"(centriole)|go:"GO:0005929"(cilium)|go:"GO:0007224"(smoothened signaling pathway)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0009953"(dorsal/ventral pattern formation)|go:"GO:0030992"(intraciliary transport particle B)|go:"GO:0031514"(motile cilium)|go:"GO:0032391"(photoreceptor connecting cilium)|go:"GO:0035720"(intraciliary anterograde transport)|go:"GO:0036064"(ciliary basal body)|go:"GO:0042073"(intraciliary transport)|go:"GO:0042733"(embryonic digit morphogenesis)|go:"GO:0044292"(dendrite terminus)|go:"GO:0050680"(negative regulation of epithelial cell proliferation)|go:"GO:0060271"(cilium assembly)|go:"GO:0070613"(regulation of protein processing)|go:"GO:0097542"(ciliary tip)|go:"GO:0097546"(ciliary base)|go:"GO:1905515"(non-motile cilium assembly)|interpro:IPR019196|interpro:IPR039975|reactome:R-HSA-5610787|reactome:R-HSA-5620924|refseq:NP_001290387.1|refseq:NP_057088.2 ensembl:ENSG00000168026(gene)|ensembl:ENST00000431162(transcript)|go:"GO:0005929"(cilium)|go:"GO:0007286"(spermatid development)|go:"GO:0030317"(flagellated sperm motility)|go:"GO:0030991"(intraciliary transport particle A)|go:"GO:0035721"(intraciliary retrograde transport)|go:"GO:0061512"(protein localization to cilium)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR019734|interpro:IPR040364|refseq:NP_001098983.2|refseq:NP_665698.2 - - - figure legend:"Figure S6 C. Co-Immunoprecipitation (Co-IP) Assays of Human Spermatozoa Revealed the Interactions between TTC21A and Known IFT Proteins."|sample process:Protein A agarose beads were used for enrichment of all the baits|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-sperm)|taxid:9606(Homo sapiens - sperm) - 2020/04/08 2020/04/08 rogid:QpeuZOrh/5/CInzF/SKBwOMUob89606 rogid:r4uyPCeaIaYrf4W4ozrfDXFIIdk9606 rigid:SkjluX23lYDGxsDWkKgz+uP8l4I false - - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot)