#ID(s) interactor A	ID(s) interactor B	Alt. ID(s) interactor A	Alt. ID(s) interactor B	Alias(es) interactor A	Alias(es) interactor B	Interaction detection method(s)	Publication 1st author(s)	Publication Identifier(s)	Taxid interactor A	Taxid interactor B	Interaction type(s)	Source database(s)	Interaction identifier(s)	Confidence value(s)	Expansion method(s)	Biological role(s) interactor A	Biological role(s) interactor B	Experimental role(s) interactor A	Experimental role(s) interactor B	Type(s) interactor A	Type(s) interactor B	Xref(s) interactor A	Xref(s) interactor B	Interaction Xref(s)	Annotation(s) interactor A	Annotation(s) interactor B	Interaction annotation(s)	Host organism(s)	Interaction parameter(s)	Creation date	Update date	Checksum(s) interactor A	Checksum(s) interactor B	Interaction Checksum(s)	Negative	Feature(s) interactor A	Feature(s) interactor B	Stoichiometry(s) interactor A	Stoichiometry(s) interactor B	Identification method participant A	Identification method participant B
uniprotkb:Q9HDC9	uniprotkb:G3H2E5	intact:EBI-723950|ensembl:ENSP00000217456|uniprotkb:Q6UVZ8|uniprotkb:Q9GZS8|uniprotkb:Q9NUB2|uniprotkb:A8K514|uniprotkb:B4DXG1	intact:EBI-26593751	psi-mi:apmap_human(display_long)|uniprotkb:Protein BSCv(gene name synonym)|uniprotkb:APMAP(gene name)|psi-mi:APMAP(display_short)|uniprotkb:C20orf3(gene name synonym)|uniprotkb:UNQ1869/PRO4305(orf name)	psi-mi:g3h2e5_crigr(display_long)|uniprotkb:I79_004355(orf name)	psi-mi:"MI:0276"(blue native page)	Gerber et al. (2019)	imex:IM-28596|pubmed:30704515	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:10029(crigr)|taxid:10029("Cricetulus griseus (Chinese hamster)")	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26573615|imex:IM-28596-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_065392.1|ensembl:ENSG00000101474(gene)|ensembl:ENST00000217456(transcript)|go:"GO:0004064"(arylesterase activity)|go:"GO:0009058"(biosynthetic process)|go:"GO:0009986"(cell surface)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016844"(strictosidine synthase activity)|interpro:IPR011042(Six-bladed beta-propeller, TolB-like)|interpro:IPR018119|mint:Q9HDC9|refseq:XP_005260820.1	go:"GO:0004930"(G protein-coupled receptor activity)|go:"GO:0004984"(olfactory receptor activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0016021"(integral component of membrane)|mint:G3H2E5|refseq:XP_003498544.1|interpro:IPR000276(GPCR, rhodopsin-like)|interpro:IPR017452(GPCR, rhodopsin-like superfamily)|interpro:IPR000725(Olfactory receptor)	-	-	-	figure legend:F3D SF4|comment:"We next designed a multistep purification procedure for the high-grade purification of APMAP and APMAP protein complexes.  he Flag-tagged APMAP and APMAP protein complexes were affinity purified following a previously described M2 anti-Flag antibody immuno-affinity procedure [40]. As a last purification step, the proteins eluted from the M2 resin were separated by size exclusion chromatography (SEC) and the fractions enriched in APMAP (Fig. (Fig.3b)3b) were further loaded onto a Blue Native gel (BN-PAGE), which allows the detection of APMAP protein complexes in their native conformations."|dataset:Alzheimers - Interactions investigated in the context of Alzheimers disease|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10029(crigr-cho)|taxid:10029(chinese hamster ovary cell line)	-	2020/12/28	2021/01/27	rogid:IRPAV+sieIBDPYsV4ypu35eSrkQ9606	rogid:W7qIxG2i2pp176D5qi+POv8f3+A10029	-	false	flag tag:c-c	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9HDC9	intact:EBI-26604532	intact:EBI-723950|ensembl:ENSP00000217456|uniprotkb:Q6UVZ8|uniprotkb:Q9GZS8|uniprotkb:Q9NUB2|uniprotkb:A8K514|uniprotkb:B4DXG1	-	psi-mi:apmap_human(display_long)|uniprotkb:Protein BSCv(gene name synonym)|uniprotkb:APMAP(gene name)|psi-mi:APMAP(display_short)|uniprotkb:C20orf3(gene name synonym)|uniprotkb:UNQ1869/PRO4305(orf name)	psi-mi:argi-1_crigr_protein(display_short)|psi-mi:EBI-26604532(display_long)	psi-mi:"MI:0276"(blue native page)	Gerber et al. (2019)	imex:IM-28596|pubmed:30704515	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:10029(crigr)|taxid:10029("Cricetulus griseus (Chinese hamster)")	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26573615|imex:IM-28596-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_065392.1|ensembl:ENSG00000101474(gene)|ensembl:ENST00000217456(transcript)|go:"GO:0004064"(arylesterase activity)|go:"GO:0009058"(biosynthetic process)|go:"GO:0009986"(cell surface)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016844"(strictosidine synthase activity)|interpro:IPR011042(Six-bladed beta-propeller, TolB-like)|interpro:IPR018119|mint:Q9HDC9|refseq:XP_005260820.1	-	-	-	-	figure legend:F3D SF4|comment:"We next designed a multistep purification procedure for the high-grade purification of APMAP and APMAP protein complexes.  he Flag-tagged APMAP and APMAP protein complexes were affinity purified following a previously described M2 anti-Flag antibody immuno-affinity procedure [40]. As a last purification step, the proteins eluted from the M2 resin were separated by size exclusion chromatography (SEC) and the fractions enriched in APMAP (Fig. (Fig.3b)3b) were further loaded onto a Blue Native gel (BN-PAGE), which allows the detection of APMAP protein complexes in their native conformations."|dataset:Alzheimers - Interactions investigated in the context of Alzheimers disease|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10029(crigr-cho)|taxid:10029(chinese hamster ovary cell line)	-	2020/12/28	2021/01/27	rogid:IRPAV+sieIBDPYsV4ypu35eSrkQ9606	-	-	false	flag tag:c-c	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9HDC9	uniprotkb:G3HYQ1	intact:EBI-723950|ensembl:ENSP00000217456|uniprotkb:Q6UVZ8|uniprotkb:Q9GZS8|uniprotkb:Q9NUB2|uniprotkb:A8K514|uniprotkb:B4DXG1	intact:EBI-26593791	psi-mi:apmap_human(display_long)|uniprotkb:Protein BSCv(gene name synonym)|uniprotkb:APMAP(gene name)|psi-mi:APMAP(display_short)|uniprotkb:C20orf3(gene name synonym)|uniprotkb:UNQ1869/PRO4305(orf name)	psi-mi:g3hyq1_crigr(display_long)|uniprotkb:I79_016192(orf name)	psi-mi:"MI:0276"(blue native page)	Gerber et al. (2019)	imex:IM-28596|pubmed:30704515	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:10029(crigr)|taxid:10029("Cricetulus griseus (Chinese hamster)")	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26573615|imex:IM-28596-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_065392.1|ensembl:ENSG00000101474(gene)|ensembl:ENST00000217456(transcript)|go:"GO:0004064"(arylesterase activity)|go:"GO:0009058"(biosynthetic process)|go:"GO:0009986"(cell surface)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016844"(strictosidine synthase activity)|interpro:IPR011042(Six-bladed beta-propeller, TolB-like)|interpro:IPR018119|mint:Q9HDC9|refseq:XP_005260820.1	go:"GO:0005737"(cytoplasm)|mint:G3HYQ1|refseq:XP_003508346.1|interpro:IPR000308(14-3-3 protein)|interpro:IPR023409|interpro:IPR036815|interpro:IPR023410	-	-	-	figure legend:F3D SF4|comment:"We next designed a multistep purification procedure for the high-grade purification of APMAP and APMAP protein complexes.  he Flag-tagged APMAP and APMAP protein complexes were affinity purified following a previously described M2 anti-Flag antibody immuno-affinity procedure [40]. As a last purification step, the proteins eluted from the M2 resin were separated by size exclusion chromatography (SEC) and the fractions enriched in APMAP (Fig. (Fig.3b)3b) were further loaded onto a Blue Native gel (BN-PAGE), which allows the detection of APMAP protein complexes in their native conformations."|dataset:Alzheimers - Interactions investigated in the context of Alzheimers disease|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10029(crigr-cho)|taxid:10029(chinese hamster ovary cell line)	-	2020/12/28	2021/01/27	rogid:IRPAV+sieIBDPYsV4ypu35eSrkQ9606	rogid:BL1D988RGBN/+NAOxWiX0PQs0N410029	-	false	flag tag:c-c	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9HDC9	intact:EBI-26604533	intact:EBI-723950|ensembl:ENSP00000217456|uniprotkb:Q6UVZ8|uniprotkb:Q9GZS8|uniprotkb:Q9NUB2|uniprotkb:A8K514|uniprotkb:B4DXG1	-	psi-mi:apmap_human(display_long)|uniprotkb:Protein BSCv(gene name synonym)|uniprotkb:APMAP(gene name)|psi-mi:APMAP(display_short)|uniprotkb:C20orf3(gene name synonym)|uniprotkb:UNQ1869/PRO4305(orf name)	psi-mi:spb3_crigr_protein(display_short)|psi-mi:EBI-26604533(display_long)	psi-mi:"MI:0276"(blue native page)	Gerber et al. (2019)	imex:IM-28596|pubmed:30704515	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:10029(crigr)|taxid:10029("Cricetulus griseus (Chinese hamster)")	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26573615|imex:IM-28596-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_065392.1|ensembl:ENSG00000101474(gene)|ensembl:ENST00000217456(transcript)|go:"GO:0004064"(arylesterase activity)|go:"GO:0009058"(biosynthetic process)|go:"GO:0009986"(cell surface)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016844"(strictosidine synthase activity)|interpro:IPR011042(Six-bladed beta-propeller, TolB-like)|interpro:IPR018119|mint:Q9HDC9|refseq:XP_005260820.1	-	-	-	comment:similar to P29508	figure legend:F3D SF4|comment:"We next designed a multistep purification procedure for the high-grade purification of APMAP and APMAP protein complexes.  he Flag-tagged APMAP and APMAP protein complexes were affinity purified following a previously described M2 anti-Flag antibody immuno-affinity procedure [40]. As a last purification step, the proteins eluted from the M2 resin were separated by size exclusion chromatography (SEC) and the fractions enriched in APMAP (Fig. (Fig.3b)3b) were further loaded onto a Blue Native gel (BN-PAGE), which allows the detection of APMAP protein complexes in their native conformations."|dataset:Alzheimers - Interactions investigated in the context of Alzheimers disease|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10029(crigr-cho)|taxid:10029(chinese hamster ovary cell line)	-	2020/12/28	2021/01/27	rogid:IRPAV+sieIBDPYsV4ypu35eSrkQ9606	-	-	false	flag tag:c-c	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9HDC9	intact:EBI-26604520	intact:EBI-723950|ensembl:ENSP00000217456|uniprotkb:Q6UVZ8|uniprotkb:Q9GZS8|uniprotkb:Q9NUB2|uniprotkb:A8K514|uniprotkb:B4DXG1	-	psi-mi:apmap_human(display_long)|uniprotkb:Protein BSCv(gene name synonym)|uniprotkb:APMAP(gene name)|psi-mi:APMAP(display_short)|uniprotkb:C20orf3(gene name synonym)|uniprotkb:UNQ1869/PRO4305(orf name)	psi-mi:clus_crigr_protein(display_short)|psi-mi:EBI-26604520(display_long)	psi-mi:"MI:0276"(blue native page)	Gerber et al. (2019)	imex:IM-28596|pubmed:30704515	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:10029(crigr)|taxid:10029("Cricetulus griseus (Chinese hamster)")	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26573615|imex:IM-28596-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_065392.1|ensembl:ENSG00000101474(gene)|ensembl:ENST00000217456(transcript)|go:"GO:0004064"(arylesterase activity)|go:"GO:0009058"(biosynthetic process)|go:"GO:0009986"(cell surface)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016844"(strictosidine synthase activity)|interpro:IPR011042(Six-bladed beta-propeller, TolB-like)|interpro:IPR018119|mint:Q9HDC9|refseq:XP_005260820.1	-	-	-	comment:similar to P10909	figure legend:F3D SF4|comment:"We next designed a multistep purification procedure for the high-grade purification of APMAP and APMAP protein complexes.  he Flag-tagged APMAP and APMAP protein complexes were affinity purified following a previously described M2 anti-Flag antibody immuno-affinity procedure [40]. As a last purification step, the proteins eluted from the M2 resin were separated by size exclusion chromatography (SEC) and the fractions enriched in APMAP (Fig. (Fig.3b)3b) were further loaded onto a Blue Native gel (BN-PAGE), which allows the detection of APMAP protein complexes in their native conformations."|dataset:Alzheimers - Interactions investigated in the context of Alzheimers disease|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10029(crigr-cho)|taxid:10029(chinese hamster ovary cell line)	-	2020/12/28	2021/01/27	rogid:IRPAV+sieIBDPYsV4ypu35eSrkQ9606	-	-	false	flag tag:c-c	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9HDC9	uniprotkb:G3HGQ1	intact:EBI-723950|ensembl:ENSP00000217456|uniprotkb:Q6UVZ8|uniprotkb:Q9GZS8|uniprotkb:Q9NUB2|uniprotkb:A8K514|uniprotkb:B4DXG1	intact:EBI-26593763	psi-mi:apmap_human(display_long)|uniprotkb:Protein BSCv(gene name synonym)|uniprotkb:APMAP(gene name)|psi-mi:APMAP(display_short)|uniprotkb:C20orf3(gene name synonym)|uniprotkb:UNQ1869/PRO4305(orf name)	psi-mi:g3hgq1_crigr(display_long)|uniprotkb:I79_009791(orf name)	psi-mi:"MI:0276"(blue native page)	Gerber et al. (2019)	imex:IM-28596|pubmed:30704515	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:10029(crigr)|taxid:10029("Cricetulus griseus (Chinese hamster)")	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26573615|imex:IM-28596-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_065392.1|ensembl:ENSG00000101474(gene)|ensembl:ENST00000217456(transcript)|go:"GO:0004064"(arylesterase activity)|go:"GO:0009058"(biosynthetic process)|go:"GO:0009986"(cell surface)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016844"(strictosidine synthase activity)|interpro:IPR011042(Six-bladed beta-propeller, TolB-like)|interpro:IPR018119|mint:Q9HDC9|refseq:XP_005260820.1	go:"GO:0005537"(mannose binding)|go:"GO:0007041"(lysosomal transport)|go:"GO:0038023"(signaling receptor activity)|interpro:IPR044865|mint:G3HGQ1|interpro:IPR000479(Cation-independent mannose-6-phosphate receptor)|interpro:IPR009011(Mannose-6-phosphate receptor, binding)	-	-	-	figure legend:F3D SF4|comment:"We next designed a multistep purification procedure for the high-grade purification of APMAP and APMAP protein complexes.  he Flag-tagged APMAP and APMAP protein complexes were affinity purified following a previously described M2 anti-Flag antibody immuno-affinity procedure [40]. As a last purification step, the proteins eluted from the M2 resin were separated by size exclusion chromatography (SEC) and the fractions enriched in APMAP (Fig. (Fig.3b)3b) were further loaded onto a Blue Native gel (BN-PAGE), which allows the detection of APMAP protein complexes in their native conformations."|dataset:Alzheimers - Interactions investigated in the context of Alzheimers disease|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10029(crigr-cho)|taxid:10029(chinese hamster ovary cell line)	-	2020/12/28	2021/01/27	rogid:IRPAV+sieIBDPYsV4ypu35eSrkQ9606	rogid:Avxk+kpdIYkua/ZwYe+VZUVevXI10029	-	false	flag tag:c-c	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9HDC9	uniprotkb:G3H902	intact:EBI-723950|ensembl:ENSP00000217456|uniprotkb:Q6UVZ8|uniprotkb:Q9GZS8|uniprotkb:Q9NUB2|uniprotkb:A8K514|uniprotkb:B4DXG1	intact:EBI-26593773	psi-mi:apmap_human(display_long)|uniprotkb:Protein BSCv(gene name synonym)|uniprotkb:APMAP(gene name)|psi-mi:APMAP(display_short)|uniprotkb:C20orf3(gene name synonym)|uniprotkb:UNQ1869/PRO4305(orf name)	psi-mi:g3h902_crigr(display_long)|uniprotkb:I79_006863(orf name)	psi-mi:"MI:0276"(blue native page)	Gerber et al. (2019)	imex:IM-28596|pubmed:30704515	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:10029(crigr)|taxid:10029("Cricetulus griseus (Chinese hamster)")	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26573615|imex:IM-28596-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_065392.1|ensembl:ENSG00000101474(gene)|ensembl:ENST00000217456(transcript)|go:"GO:0004064"(arylesterase activity)|go:"GO:0009058"(biosynthetic process)|go:"GO:0009986"(cell surface)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016844"(strictosidine synthase activity)|interpro:IPR011042(Six-bladed beta-propeller, TolB-like)|interpro:IPR018119|mint:Q9HDC9|refseq:XP_005260820.1	go:"GO:0016021"(integral component of membrane)|mint:G3H902|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR036179|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR003599(Immunoglobulin subtype)|interpro:IPR013106(Immunoglobulin V-set)	-	-	-	figure legend:F3D SF4|comment:"We next designed a multistep purification procedure for the high-grade purification of APMAP and APMAP protein complexes.  he Flag-tagged APMAP and APMAP protein complexes were affinity purified following a previously described M2 anti-Flag antibody immuno-affinity procedure [40]. As a last purification step, the proteins eluted from the M2 resin were separated by size exclusion chromatography (SEC) and the fractions enriched in APMAP (Fig. (Fig.3b)3b) were further loaded onto a Blue Native gel (BN-PAGE), which allows the detection of APMAP protein complexes in their native conformations."|dataset:Alzheimers - Interactions investigated in the context of Alzheimers disease|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10029(crigr-cho)|taxid:10029(chinese hamster ovary cell line)	-	2020/12/28	2021/01/27	rogid:IRPAV+sieIBDPYsV4ypu35eSrkQ9606	rogid:lvvFV4w5Q9ZS0kx7sylb7Lua3p410029	-	false	flag tag:c-c	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9HDC9	uniprotkb:G3H7X9	intact:EBI-723950|ensembl:ENSP00000217456|uniprotkb:Q6UVZ8|uniprotkb:Q9GZS8|uniprotkb:Q9NUB2|uniprotkb:A8K514|uniprotkb:B4DXG1	intact:EBI-26593783	psi-mi:apmap_human(display_long)|uniprotkb:Protein BSCv(gene name synonym)|uniprotkb:APMAP(gene name)|psi-mi:APMAP(display_short)|uniprotkb:C20orf3(gene name synonym)|uniprotkb:UNQ1869/PRO4305(orf name)	psi-mi:g3h7x9_crigr(display_long)|uniprotkb:I79_006475(orf name)	psi-mi:"MI:0276"(blue native page)	Gerber et al. (2019)	imex:IM-28596|pubmed:30704515	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:10029(crigr)|taxid:10029("Cricetulus griseus (Chinese hamster)")	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26573615|imex:IM-28596-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_065392.1|ensembl:ENSG00000101474(gene)|ensembl:ENST00000217456(transcript)|go:"GO:0004064"(arylesterase activity)|go:"GO:0009058"(biosynthetic process)|go:"GO:0009986"(cell surface)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016844"(strictosidine synthase activity)|interpro:IPR011042(Six-bladed beta-propeller, TolB-like)|interpro:IPR018119|mint:Q9HDC9|refseq:XP_005260820.1	go:"GO:0016021"(integral component of membrane)|go:"GO:0016485"(protein processing)|mint:G3H7X9|interpro:IPR041084|interpro:IPR008710(Nicastrin)	-	-	-	figure legend:F3D SF4|comment:"We next designed a multistep purification procedure for the high-grade purification of APMAP and APMAP protein complexes.  he Flag-tagged APMAP and APMAP protein complexes were affinity purified following a previously described M2 anti-Flag antibody immuno-affinity procedure [40]. As a last purification step, the proteins eluted from the M2 resin were separated by size exclusion chromatography (SEC) and the fractions enriched in APMAP (Fig. (Fig.3b)3b) were further loaded onto a Blue Native gel (BN-PAGE), which allows the detection of APMAP protein complexes in their native conformations."|dataset:Alzheimers - Interactions investigated in the context of Alzheimers disease|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10029(crigr-cho)|taxid:10029(chinese hamster ovary cell line)	-	2020/12/28	2021/01/27	rogid:IRPAV+sieIBDPYsV4ypu35eSrkQ9606	rogid:UB7PtlumXDHfpA2mULVfCDDQBac10029	-	false	flag tag:c-c	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9HDC9	uniprotkb:P49129	intact:EBI-723950|ensembl:ENSP00000217456|uniprotkb:Q6UVZ8|uniprotkb:Q9GZS8|uniprotkb:Q9NUB2|uniprotkb:A8K514|uniprotkb:B4DXG1	intact:EBI-26573597|ensembl:ENSCGRP00001004655	psi-mi:apmap_human(display_long)|uniprotkb:Protein BSCv(gene name synonym)|uniprotkb:APMAP(gene name)|psi-mi:APMAP(display_short)|uniprotkb:C20orf3(gene name synonym)|uniprotkb:UNQ1869/PRO4305(orf name)	psi-mi:lamp1_crigr(display_long)|uniprotkb:CD107 antigen-like family member A(gene name synonym)|uniprotkb:Lysosomal membrane glycoprotein A(gene name synonym)|uniprotkb:LAMP1(gene name)|psi-mi:LAMP1(display_short)|uniprotkb:LGPA(gene name synonym)	psi-mi:"MI:0276"(blue native page)	Gerber et al. (2019)	imex:IM-28596|pubmed:30704515	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:10029(crigr)|taxid:10029("Cricetulus griseus (Chinese hamster)")	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26573615|imex:IM-28596-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_065392.1|ensembl:ENSG00000101474(gene)|ensembl:ENST00000217456(transcript)|go:"GO:0004064"(arylesterase activity)|go:"GO:0009058"(biosynthetic process)|go:"GO:0009986"(cell surface)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016844"(strictosidine synthase activity)|interpro:IPR011042(Six-bladed beta-propeller, TolB-like)|interpro:IPR018119|mint:Q9HDC9|refseq:XP_005260820.1	refseq:NP_001233759.1|ensembl:ENSCGRG00001005956(gene)|ensembl:ENSCGRT00001007016(transcript)|go:"GO:0005764"(lysosome)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005886"(plasma membrane)|go:"GO:0010008"(endosome membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0050821"(protein stabilization)|go:"GO:0101004"(cytolytic granule membrane)|interpro:IPR002000("Lysosome-associated membrane glycoprotein (Lamp)/CD68")|interpro:IPR018134|mint:P49129|go:"GO:0031902"(late endosome membrane)	-	-	-	figure legend:F3D SF4|comment:"We next designed a multistep purification procedure for the high-grade purification of APMAP and APMAP protein complexes.  he Flag-tagged APMAP and APMAP protein complexes were affinity purified following a previously described M2 anti-Flag antibody immuno-affinity procedure [40]. As a last purification step, the proteins eluted from the M2 resin were separated by size exclusion chromatography (SEC) and the fractions enriched in APMAP (Fig. (Fig.3b)3b) were further loaded onto a Blue Native gel (BN-PAGE), which allows the detection of APMAP protein complexes in their native conformations."|dataset:Alzheimers - Interactions investigated in the context of Alzheimers disease|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10029(crigr-cho)|taxid:10029(chinese hamster ovary cell line)	-	2020/12/28	2021/01/27	rogid:IRPAV+sieIBDPYsV4ypu35eSrkQ9606	rogid:LKDrwtJDwZt1qdOHLWpN+VXixQE10029	-	false	flag tag:c-c	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9HDC9	intact:EBI-26604531	intact:EBI-723950|ensembl:ENSP00000217456|uniprotkb:Q6UVZ8|uniprotkb:Q9GZS8|uniprotkb:Q9NUB2|uniprotkb:A8K514|uniprotkb:B4DXG1	-	psi-mi:apmap_human(display_long)|uniprotkb:Protein BSCv(gene name synonym)|uniprotkb:APMAP(gene name)|psi-mi:APMAP(display_short)|uniprotkb:C20orf3(gene name synonym)|uniprotkb:UNQ1869/PRO4305(orf name)	psi-mi:mbrl_crigr_protein(display_short)|psi-mi:EBI-26604531(display_long)	psi-mi:"MI:0276"(blue native page)	Gerber et al. (2019)	imex:IM-28596|pubmed:30704515	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:10029(crigr)|taxid:10029("Cricetulus griseus (Chinese hamster)")	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26573615|imex:IM-28596-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_065392.1|ensembl:ENSG00000101474(gene)|ensembl:ENST00000217456(transcript)|go:"GO:0004064"(arylesterase activity)|go:"GO:0009058"(biosynthetic process)|go:"GO:0009986"(cell surface)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016844"(strictosidine synthase activity)|interpro:IPR011042(Six-bladed beta-propeller, TolB-like)|interpro:IPR018119|mint:Q9HDC9|refseq:XP_005260820.1	-	-	-	comment:similar to F1LPC5	figure legend:F3D SF4|comment:"We next designed a multistep purification procedure for the high-grade purification of APMAP and APMAP protein complexes.  he Flag-tagged APMAP and APMAP protein complexes were affinity purified following a previously described M2 anti-Flag antibody immuno-affinity procedure [40]. As a last purification step, the proteins eluted from the M2 resin were separated by size exclusion chromatography (SEC) and the fractions enriched in APMAP (Fig. (Fig.3b)3b) were further loaded onto a Blue Native gel (BN-PAGE), which allows the detection of APMAP protein complexes in their native conformations."|dataset:Alzheimers - Interactions investigated in the context of Alzheimers disease|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10029(crigr-cho)|taxid:10029(chinese hamster ovary cell line)	-	2020/12/28	2021/01/27	rogid:IRPAV+sieIBDPYsV4ypu35eSrkQ9606	-	-	false	flag tag:c-c	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9HDC9	intact:EBI-26602939	intact:EBI-723950|ensembl:ENSP00000217456|uniprotkb:Q6UVZ8|uniprotkb:Q9GZS8|uniprotkb:Q9NUB2|uniprotkb:A8K514|uniprotkb:B4DXG1	-	psi-mi:apmap_human(display_long)|uniprotkb:Protein BSCv(gene name synonym)|uniprotkb:APMAP(gene name)|psi-mi:APMAP(display_short)|uniprotkb:C20orf3(gene name synonym)|uniprotkb:UNQ1869/PRO4305(orf name)	psi-mi:fetua_crigr_protein(display_short)|psi-mi:EBI-26602939(display_long)	psi-mi:"MI:0276"(blue native page)	Gerber et al. (2019)	imex:IM-28596|pubmed:30704515	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:10029(crigr)|taxid:10029("Cricetulus griseus (Chinese hamster)")	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26573615|imex:IM-28596-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_065392.1|ensembl:ENSG00000101474(gene)|ensembl:ENST00000217456(transcript)|go:"GO:0004064"(arylesterase activity)|go:"GO:0009058"(biosynthetic process)|go:"GO:0009986"(cell surface)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016844"(strictosidine synthase activity)|interpro:IPR011042(Six-bladed beta-propeller, TolB-like)|interpro:IPR018119|mint:Q9HDC9|refseq:XP_005260820.1	-	-	-	comment:similar to P02765	figure legend:F3D SF4|comment:"We next designed a multistep purification procedure for the high-grade purification of APMAP and APMAP protein complexes.  he Flag-tagged APMAP and APMAP protein complexes were affinity purified following a previously described M2 anti-Flag antibody immuno-affinity procedure [40]. As a last purification step, the proteins eluted from the M2 resin were separated by size exclusion chromatography (SEC) and the fractions enriched in APMAP (Fig. (Fig.3b)3b) were further loaded onto a Blue Native gel (BN-PAGE), which allows the detection of APMAP protein complexes in their native conformations."|dataset:Alzheimers - Interactions investigated in the context of Alzheimers disease|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10029(crigr-cho)|taxid:10029(chinese hamster ovary cell line)	-	2020/12/28	2021/01/27	rogid:IRPAV+sieIBDPYsV4ypu35eSrkQ9606	-	-	false	flag tag:c-c	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9HDC9	uniprotkb:A0A061I3K8	intact:EBI-723950|ensembl:ENSP00000217456|uniprotkb:Q6UVZ8|uniprotkb:Q9GZS8|uniprotkb:Q9NUB2|uniprotkb:A8K514|uniprotkb:B4DXG1	intact:EBI-26593738	psi-mi:apmap_human(display_long)|uniprotkb:Protein BSCv(gene name synonym)|uniprotkb:APMAP(gene name)|psi-mi:APMAP(display_short)|uniprotkb:C20orf3(gene name synonym)|uniprotkb:UNQ1869/PRO4305(orf name)	psi-mi:a0a061i3k8_crigr(display_long)|uniprotkb:H671_7g18220(orf name)	psi-mi:"MI:0276"(blue native page)	Gerber et al. (2019)	imex:IM-28596|pubmed:30704515	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:10029(crigr)|taxid:10029("Cricetulus griseus (Chinese hamster)")	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26573615|imex:IM-28596-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_065392.1|ensembl:ENSG00000101474(gene)|ensembl:ENST00000217456(transcript)|go:"GO:0004064"(arylesterase activity)|go:"GO:0009058"(biosynthetic process)|go:"GO:0009986"(cell surface)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016844"(strictosidine synthase activity)|interpro:IPR011042(Six-bladed beta-propeller, TolB-like)|interpro:IPR018119|mint:Q9HDC9|refseq:XP_005260820.1	go:"GO:0005509"(calcium ion binding)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0006457"(protein folding)|go:"GO:0051082"(unfolded protein binding)|mint:A0A061I3K8|interpro:IPR001580(Calreticulin/calnexin)|interpro:IPR018124|interpro:IPR009033(Calreticulin/calnexin, P)|interpro:IPR013320(Concanavalin A-like lectin/glucanase, subgroup)	-	-	-	figure legend:F3D SF4|comment:"We next designed a multistep purification procedure for the high-grade purification of APMAP and APMAP protein complexes.  he Flag-tagged APMAP and APMAP protein complexes were affinity purified following a previously described M2 anti-Flag antibody immuno-affinity procedure [40]. As a last purification step, the proteins eluted from the M2 resin were separated by size exclusion chromatography (SEC) and the fractions enriched in APMAP (Fig. (Fig.3b)3b) were further loaded onto a Blue Native gel (BN-PAGE), which allows the detection of APMAP protein complexes in their native conformations."|dataset:Alzheimers - Interactions investigated in the context of Alzheimers disease|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10029(crigr-cho)|taxid:10029(chinese hamster ovary cell line)	-	2020/12/28	2021/01/27	rogid:IRPAV+sieIBDPYsV4ypu35eSrkQ9606	rogid:KGdb1MbqYCb4PjUutrJlvG/XVEA10029	-	false	flag tag:c-c	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q9HDC9	intact:EBI-26604519	intact:EBI-723950|ensembl:ENSP00000217456|uniprotkb:Q6UVZ8|uniprotkb:Q9GZS8|uniprotkb:Q9NUB2|uniprotkb:A8K514|uniprotkb:B4DXG1	-	psi-mi:apmap_human(display_long)|uniprotkb:Protein BSCv(gene name synonym)|uniprotkb:APMAP(gene name)|psi-mi:APMAP(display_short)|uniprotkb:C20orf3(gene name synonym)|uniprotkb:UNQ1869/PRO4305(orf name)	psi-mi:rtn4_crigr_protein(display_short)|psi-mi:EBI-26604519(display_long)	psi-mi:"MI:0276"(blue native page)	Gerber et al. (2019)	imex:IM-28596|pubmed:30704515	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:10029(crigr)|taxid:10029("Cricetulus griseus (Chinese hamster)")	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26573615|imex:IM-28596-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_065392.1|ensembl:ENSG00000101474(gene)|ensembl:ENST00000217456(transcript)|go:"GO:0004064"(arylesterase activity)|go:"GO:0009058"(biosynthetic process)|go:"GO:0009986"(cell surface)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016844"(strictosidine synthase activity)|interpro:IPR011042(Six-bladed beta-propeller, TolB-like)|interpro:IPR018119|mint:Q9HDC9|refseq:XP_005260820.1	-	-	-	-	figure legend:F3D SF4|comment:"We next designed a multistep purification procedure for the high-grade purification of APMAP and APMAP protein complexes.  he Flag-tagged APMAP and APMAP protein complexes were affinity purified following a previously described M2 anti-Flag antibody immuno-affinity procedure [40]. As a last purification step, the proteins eluted from the M2 resin were separated by size exclusion chromatography (SEC) and the fractions enriched in APMAP (Fig. (Fig.3b)3b) were further loaded onto a Blue Native gel (BN-PAGE), which allows the detection of APMAP protein complexes in their native conformations."|dataset:Alzheimers - Interactions investigated in the context of Alzheimers disease|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10029(crigr-cho)|taxid:10029(chinese hamster ovary cell line)	-	2020/12/28	2021/01/27	rogid:IRPAV+sieIBDPYsV4ypu35eSrkQ9606	-	-	false	flag tag:c-c	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)