#ID(s) interactor A	ID(s) interactor B	Alt. ID(s) interactor A	Alt. ID(s) interactor B	Alias(es) interactor A	Alias(es) interactor B	Interaction detection method(s)	Publication 1st author(s)	Publication Identifier(s)	Taxid interactor A	Taxid interactor B	Interaction type(s)	Source database(s)	Interaction identifier(s)	Confidence value(s)	Expansion method(s)	Biological role(s) interactor A	Biological role(s) interactor B	Experimental role(s) interactor A	Experimental role(s) interactor B	Type(s) interactor A	Type(s) interactor B	Xref(s) interactor A	Xref(s) interactor B	Interaction Xref(s)	Annotation(s) interactor A	Annotation(s) interactor B	Interaction annotation(s)	Host organism(s)	Interaction parameter(s)	Creation date	Update date	Checksum(s) interactor A	Checksum(s) interactor B	Interaction Checksum(s)	Negative	Feature(s) interactor A	Feature(s) interactor B	Stoichiometry(s) interactor A	Stoichiometry(s) interactor B	Identification method participant A	Identification method participant B
uniprotkb:P9WJG3	uniprotkb:P9WHJ5	intact:EBI-6421028|uniprotkb:O53568|uniprotkb:F2GJS9|uniprotkb:Q7D585|uniprotkb:L0TFY0	intact:EBI-25396356|uniprotkb:L7N5Z6	psi-mi:card_myctu(display_long)|uniprotkb:carD(gene name)|psi-mi:carD(display_short)|uniprotkb:Rv3583c(locus name)	psi-mi:rbpa_myctu(display_long)|uniprotkb:rbpA(gene name)|psi-mi:rbpA(display_short)|uniprotkb:Rv2050(locus name)	psi-mi:"MI:0410"(3D electron microscopy)	Boyaci et al. (2019)	imex:IM-27849|pubmed:30626968	taxid:83332(myctu)|taxid:83332("Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)")	taxid:83332(myctu)|taxid:83332("Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)")	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0465"(DIP)	intact:EBI-25396352|emdb:EMD-9041|wwpdb:6EDT|emdb:EMD-9037|wwpdb:6EE8|emdb:EMD-9039|wwpdb:6EEC|imex:IM-27849-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	rcsb pdb:4ILU|rcsb pdb:4MFR|go:"GO:0015968"(stringent response)|go:"GO:0040009"(regulation of growth rate)|rcsb pdb:4KMC|rcsb pdb:6VVX|rcsb pdb:6VVY|rcsb pdb:6VVZ|rcsb pdb:6VW0|refseq:WP_003419482.1|interpro:IPR003711(Transcription factor CarD)|refseq:NP_218100.1|rcsb pdb:4KBM|interpro:IPR042215|rcsb pdb:6EDT|rcsb pdb:6EE8|rcsb pdb:6EEC|interpro:IPR036101	go:"GO:0001000"(bacterial-type RNA polymerase core enzyme binding)|go:"GO:0001108"(bacterial-type RNA polymerase holo enzyme binding)|go:"GO:0005618"(cell wall)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|refseq:NP_216566.1|refseq:WP_003410601.1|rcsb pdb:2M4V|rcsb pdb:2M6P|rcsb pdb:4X8K|rcsb pdb:6BZO|rcsb pdb:6C04|rcsb pdb:6C05|rcsb pdb:6C06|rcsb pdb:6EDT|rcsb pdb:6EE8|rcsb pdb:6EEC|rcsb pdb:6M7J|interpro:IPR038638|interpro:IPR025182|rcsb pdb:6VVX|rcsb pdb:6VVY|rcsb pdb:6VVZ|rcsb pdb:6VW0	-	crc64:15F27E0732FD6AD7	-	figure legend:Fig 1, Extended Data Fig 2, 3, Extended Data Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2020/01/10	2020/03/13	rogid:v2h+wJJmq9HObjLJEmmAcQjWdKg83332	rogid:m2PqpKD1I/Rc/KsveEm4GTXeoU083332	rigid:VcCwdmSYyU+WQQQHcsvPwlpQACE	false	-	-	1	1	psi-mi:"MI:0396"(predetermined participant)|psi-mi:"MI:2287"(identification by structure determination)	psi-mi:"MI:0396"(predetermined participant)|psi-mi:"MI:2287"(identification by structure determination)
uniprotkb:P9WJG3	uniprotkb:P9WGZ1	intact:EBI-6421028|uniprotkb:O53568|uniprotkb:F2GJS9|uniprotkb:Q7D585|uniprotkb:L0TFY0	intact:EBI-6417848|uniprotkb:P66701|uniprotkb:O06324|uniprotkb:L0TCT4	psi-mi:card_myctu(display_long)|uniprotkb:carD(gene name)|psi-mi:carD(display_short)|uniprotkb:Rv3583c(locus name)	psi-mi:rpoa_myctu(display_long)|uniprotkb:rpoA(gene name)|psi-mi:rpoA(display_short)|uniprotkb:RNA polymerase subunit alpha(gene name synonym)|uniprotkb:Transcriptase subunit alpha(gene name synonym)|uniprotkb:MTCY13E12.10c(orf name)|uniprotkb:Rv3457c(locus name)	psi-mi:"MI:0410"(3D electron microscopy)	Boyaci et al. (2019)	imex:IM-27849|pubmed:30626968	taxid:83332(myctu)|taxid:83332("Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)")	taxid:83332(myctu)|taxid:83332("Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)")	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0465"(DIP)	intact:EBI-25396352|emdb:EMD-9041|wwpdb:6EDT|emdb:EMD-9037|wwpdb:6EE8|emdb:EMD-9039|wwpdb:6EEC|imex:IM-27849-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	rcsb pdb:4ILU|rcsb pdb:4MFR|go:"GO:0015968"(stringent response)|go:"GO:0040009"(regulation of growth rate)|rcsb pdb:4KMC|rcsb pdb:6VVX|rcsb pdb:6VVY|rcsb pdb:6VVZ|rcsb pdb:6VW0|refseq:WP_003419482.1|interpro:IPR003711(Transcription factor CarD)|refseq:NP_218100.1|rcsb pdb:4KBM|interpro:IPR042215|rcsb pdb:6EDT|rcsb pdb:6EE8|rcsb pdb:6EEC|interpro:IPR036101	rcsb pdb:6BZO|rcsb pdb:6C04|rcsb pdb:6C05|rcsb pdb:6TYE|rcsb pdb:6TYF|rcsb pdb:6TYG|go:"GO:0003677"(DNA binding)|go:"GO:0003899"(DNA-directed 5'-3' RNA polymerase activity)|go:"GO:0005618"(cell wall)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0046983"(protein dimerization activity)|rcsb pdb:6C06|interpro:IPR036643|rcsb pdb:6VVX|rcsb pdb:6VVY|rcsb pdb:6VVZ|rcsb pdb:6VW0|rcsb pdb:6FBV|interpro:IPR011260(RNA polymerase, alpha subunit, C-terminal)|interpro:IPR011262(DNA-directed RNA polymerase, insert)|interpro:IPR011263(DNA-directed RNA polymerase, RpoA/D/Rpb3-type)|interpro:IPR011773(DNA-directed RNA polymerase, alpha subunit)|refseq:NP_217974.1|refseq:WP_003418351.1|interpro:IPR036603|rcsb pdb:5UH5|rcsb pdb:5UH6|rcsb pdb:5UH8|rcsb pdb:5UH9|rcsb pdb:5UHA|rcsb pdb:5UHB|rcsb pdb:5UHC|rcsb pdb:5UHD|rcsb pdb:5UHE|rcsb pdb:5UHF|rcsb pdb:5UHG|rcsb pdb:5ZX2|rcsb pdb:5ZX3|rcsb pdb:6EDT|rcsb pdb:6EE8|rcsb pdb:6EEC|rcsb pdb:6JCX|rcsb pdb:6JCY|rcsb pdb:6DV9|rcsb pdb:6DVB|rcsb pdb:6DVC|rcsb pdb:6DVD|rcsb pdb:6DVE|reactome:R-HSA-9639775|rcsb pdb:6KON|rcsb pdb:6KOO|rcsb pdb:6KOP|rcsb pdb:6KOQ	-	crc64:15F27E0732FD6AD7	-	figure legend:Fig 1, Extended Data Fig 2, 3, Extended Data Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2020/01/10	2020/03/13	rogid:v2h+wJJmq9HObjLJEmmAcQjWdKg83332	rogid:LTBkYO0JRDnFzCI5CB7/T6ZQ+LQ83332	rigid:VcCwdmSYyU+WQQQHcsvPwlpQACE	false	-	-	1	1	psi-mi:"MI:0396"(predetermined participant)|psi-mi:"MI:2287"(identification by structure determination)	psi-mi:"MI:0396"(predetermined participant)|psi-mi:"MI:2287"(identification by structure determination)
uniprotkb:P9WJG3	uniprotkb:P9WGY7	intact:EBI-6421028|uniprotkb:O53568|uniprotkb:F2GJS9|uniprotkb:Q7D585|uniprotkb:L0TFY0	intact:EBI-6429487|uniprotkb:P0A674|uniprotkb:O06771|uniprotkb:P47769|uniprotkb:L0T4I2	psi-mi:card_myctu(display_long)|uniprotkb:carD(gene name)|psi-mi:carD(display_short)|uniprotkb:Rv3583c(locus name)	psi-mi:rpoc_myctu(display_long)|uniprotkb:rpoC(gene name)|psi-mi:rpoC(display_short)|uniprotkb:RNA polymerase subunit beta'(gene name synonym)|uniprotkb:Transcriptase subunit beta'(gene name synonym)|uniprotkb:MTCI376.07c(orf name)|uniprotkb:Rv0668(locus name)	psi-mi:"MI:0410"(3D electron microscopy)	Boyaci et al. (2019)	imex:IM-27849|pubmed:30626968	taxid:83332(myctu)|taxid:83332("Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)")	taxid:83332(myctu)|taxid:83332("Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)")	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0465"(DIP)	intact:EBI-25396352|emdb:EMD-9041|wwpdb:6EDT|emdb:EMD-9037|wwpdb:6EE8|emdb:EMD-9039|wwpdb:6EEC|imex:IM-27849-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	rcsb pdb:4ILU|rcsb pdb:4MFR|go:"GO:0015968"(stringent response)|go:"GO:0040009"(regulation of growth rate)|rcsb pdb:4KMC|rcsb pdb:6VVX|rcsb pdb:6VVY|rcsb pdb:6VVZ|rcsb pdb:6VW0|refseq:WP_003419482.1|interpro:IPR003711(Transcription factor CarD)|refseq:NP_218100.1|rcsb pdb:4KBM|interpro:IPR042215|rcsb pdb:6EDT|rcsb pdb:6EE8|rcsb pdb:6EEC|interpro:IPR036101	rcsb pdb:6BZO|rcsb pdb:6C04|rcsb pdb:6C05|rcsb pdb:6TYE|go:"GO:0000287"(magnesium ion binding)|go:"GO:0003677"(DNA binding)|go:"GO:0003899"(DNA-directed 5'-3' RNA polymerase activity)|go:"GO:0005618"(cell wall)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0008270"(zinc ion binding)|rcsb pdb:6C06|rcsb pdb:6VVX|rcsb pdb:6VVY|rcsb pdb:6VVZ|rcsb pdb:6VW0|rcsb pdb:6FBV|refseq:WP_003403413.1|rcsb pdb:6TYF|rcsb pdb:6TYG|refseq:NP_215182.1|interpro:IPR012754(DNA-directed RNA polymerase, subunit beta-prime)|interpro:IPR000722(RNA polymerase, alpha subunit)|interpro:IPR006592(RNA polymerase, N-terminal)|interpro:IPR007080(RNA polymerase Rpb1, domain 1)|interpro:IPR007066(RNA polymerase Rpb1, domain 3)|interpro:IPR007083(RNA polymerase Rpb1, domain 4)|interpro:IPR007081(RNA polymerase Rpb1, domain 5)|rcsb pdb:5UH5|rcsb pdb:5UH6|rcsb pdb:5UH7|rcsb pdb:5UH8|rcsb pdb:5UH9|rcsb pdb:5UHA|rcsb pdb:5UHB|rcsb pdb:5UHC|rcsb pdb:5UHD|rcsb pdb:5UHE|rcsb pdb:5UHF|rcsb pdb:5UHG|rcsb pdb:5ZX2|rcsb pdb:5ZX3|rcsb pdb:6EDT|rcsb pdb:6EE8|rcsb pdb:6EEC|rcsb pdb:6M7J|interpro:IPR038120|rcsb pdb:6JCX|rcsb pdb:6JCY|interpro:IPR042102|rcsb pdb:6DV9|rcsb pdb:6DVB|rcsb pdb:6DVC|rcsb pdb:6DVD|rcsb pdb:6DVE|reactome:R-HSA-9639775|rcsb pdb:6KON|rcsb pdb:6KOO|rcsb pdb:6KOP|rcsb pdb:6KOQ	-	crc64:15F27E0732FD6AD7	-	figure legend:Fig 1, Extended Data Fig 2, 3, Extended Data Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2020/01/10	2020/03/13	rogid:v2h+wJJmq9HObjLJEmmAcQjWdKg83332	rogid:QoDUBgmHeTU4+HwWBYkj21i1Doc83332	rigid:VcCwdmSYyU+WQQQHcsvPwlpQACE	false	-	-	1	1	psi-mi:"MI:0396"(predetermined participant)|psi-mi:"MI:2287"(identification by structure determination)	psi-mi:"MI:0396"(predetermined participant)|psi-mi:"MI:2287"(identification by structure determination)
uniprotkb:P9WJG3	uniprotkb:P9WGY5	intact:EBI-6421028|uniprotkb:O53568|uniprotkb:F2GJS9|uniprotkb:Q7D585|uniprotkb:L0TFY0	intact:EBI-6429563|uniprotkb:P66721|uniprotkb:P71660|uniprotkb:L0T993	psi-mi:card_myctu(display_long)|uniprotkb:carD(gene name)|psi-mi:carD(display_short)|uniprotkb:Rv3583c(locus name)	psi-mi:rpoz_myctu(display_long)|uniprotkb:rpoZ(gene name)|psi-mi:rpoZ(display_short)|uniprotkb:RNA polymerase omega subunit(gene name synonym)|uniprotkb:Transcriptase subunit omega(gene name synonym)|uniprotkb:MTCY21B4.07(orf name)|uniprotkb:Rv1390(locus name)	psi-mi:"MI:0410"(3D electron microscopy)	Boyaci et al. (2019)	imex:IM-27849|pubmed:30626968	taxid:83332(myctu)|taxid:83332("Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)")	taxid:83332(myctu)|taxid:83332("Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)")	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0465"(DIP)	intact:EBI-25396352|emdb:EMD-9041|wwpdb:6EDT|emdb:EMD-9037|wwpdb:6EE8|emdb:EMD-9039|wwpdb:6EEC|imex:IM-27849-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	rcsb pdb:4ILU|rcsb pdb:4MFR|go:"GO:0015968"(stringent response)|go:"GO:0040009"(regulation of growth rate)|rcsb pdb:4KMC|rcsb pdb:6VVX|rcsb pdb:6VVY|rcsb pdb:6VVZ|rcsb pdb:6VW0|refseq:WP_003419482.1|interpro:IPR003711(Transcription factor CarD)|refseq:NP_218100.1|rcsb pdb:4KBM|interpro:IPR042215|rcsb pdb:6EDT|rcsb pdb:6EE8|rcsb pdb:6EEC|interpro:IPR036101	rcsb pdb:6BZO|rcsb pdb:6C04|rcsb pdb:6C05|rcsb pdb:6C06|go:"GO:0003677"(DNA binding)|go:"GO:0003899"(DNA-directed 5'-3' RNA polymerase activity)|go:"GO:0005618"(cell wall)|go:"GO:0005829"(cytosol)|go:"GO:0006351"(transcription, DNA-templated)|rcsb pdb:6VVX|rcsb pdb:6VVY|rcsb pdb:6VVZ|rcsb pdb:6VW0|rcsb pdb:6FBV|refseq:WP_003407248.1|refseq:NP_215906.1|interpro:IPR003716(RNA polymerase, omega subunit)|interpro:IPR006110(RNA polymerase Rpb6)|interpro:IPR012293(RNA polymerase subunit, RPB6/omega)|rcsb pdb:6TYE|rcsb pdb:6TYF|rcsb pdb:6TYG|rcsb pdb:5UH5|rcsb pdb:5UH6|rcsb pdb:5UH8|rcsb pdb:5UH9|rcsb pdb:5UHA|rcsb pdb:5UHB|rcsb pdb:5UHC|rcsb pdb:5UHD|rcsb pdb:5UHE|rcsb pdb:5UHF|rcsb pdb:5UHG|rcsb pdb:5ZX2|rcsb pdb:5ZX3|rcsb pdb:6EDT|rcsb pdb:6EE8|rcsb pdb:6EEC|rcsb pdb:6M7J|interpro:IPR036161|rcsb pdb:6JCX|rcsb pdb:6JCY|rcsb pdb:6DV9|rcsb pdb:6DVB|rcsb pdb:6DVC|rcsb pdb:6DVD|rcsb pdb:6DVE|reactome:R-HSA-9639775|rcsb pdb:6KON|rcsb pdb:6KOO|rcsb pdb:6KOP|rcsb pdb:6KOQ	-	crc64:15F27E0732FD6AD7	-	figure legend:Fig 1, Extended Data Fig 2, 3, Extended Data Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2020/01/10	2020/03/13	rogid:v2h+wJJmq9HObjLJEmmAcQjWdKg83332	rogid:vGl8przz7lgqXNpNmTl5lvScP2o83332	rigid:VcCwdmSYyU+WQQQHcsvPwlpQACE	false	-	-	1	1	psi-mi:"MI:0396"(predetermined participant)|psi-mi:"MI:2287"(identification by structure determination)	psi-mi:"MI:0396"(predetermined participant)|psi-mi:"MI:2287"(identification by structure determination)
uniprotkb:P9WJG3	uniprotkb:P9WGI1	intact:EBI-6421028|uniprotkb:O53568|uniprotkb:F2GJS9|uniprotkb:Q7D585|uniprotkb:L0TFY0	intact:EBI-11859464|uniprotkb:L0TAM5|uniprotkb:O08495|uniprotkb:O08513|uniprotkb:P0A602|uniprotkb:Q60162	psi-mi:card_myctu(display_long)|uniprotkb:carD(gene name)|psi-mi:carD(display_short)|uniprotkb:Rv3583c(locus name)	psi-mi:siga_myctu(display_long)|uniprotkb:sigA(gene name)|psi-mi:sigA(display_short)|uniprotkb:mysA(gene name synonym)|uniprotkb:rpoD(gene name synonym)|uniprotkb:rpoV(gene name synonym)|uniprotkb:MTCY05A6.24(orf name)|uniprotkb:Rv2703(locus name)	psi-mi:"MI:0410"(3D electron microscopy)	Boyaci et al. (2019)	imex:IM-27849|pubmed:30626968	taxid:83332(myctu)|taxid:83332("Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)")	taxid:83332(myctu)|taxid:83332("Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)")	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0465"(DIP)	intact:EBI-25396352|emdb:EMD-9041|wwpdb:6EDT|emdb:EMD-9037|wwpdb:6EE8|emdb:EMD-9039|wwpdb:6EEC|imex:IM-27849-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	rcsb pdb:4ILU|rcsb pdb:4MFR|go:"GO:0015968"(stringent response)|go:"GO:0040009"(regulation of growth rate)|rcsb pdb:4KMC|rcsb pdb:6VVX|rcsb pdb:6VVY|rcsb pdb:6VVZ|rcsb pdb:6VW0|refseq:WP_003419482.1|interpro:IPR003711(Transcription factor CarD)|refseq:NP_218100.1|rcsb pdb:4KBM|interpro:IPR042215|rcsb pdb:6EDT|rcsb pdb:6EE8|rcsb pdb:6EEC|interpro:IPR036101	refseq:NP_217219.1|refseq:WP_003413944.1|rcsb pdb:4X8K|interpro:IPR014284(RNA polymerase sigma-70)|interpro:IPR000943(RNA polymerase sigma-70 factor)|interpro:IPR009042(RNA polymerase sigma-70 region 1.2)|interpro:IPR007627(RNA polymerase sigma-70 region 2)|interpro:IPR007624(RNA polymerase sigma-70 region 3)|interpro:IPR007630(RNA polymerase sigma-70 region 4)|interpro:IPR013325(RNA polymerase sigma factor, region 2)|interpro:IPR013324(RNA polymerase sigma factor, regions 3 and 4)|interpro:IPR012760(RNA polymerase sigma factor RpoD, C-terminal)|interpro:IPR028630|rcsb pdb:6FBV|go:"GO:0001123"|go:"GO:0003677"(DNA binding)|go:"GO:0005618"(cell wall)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0009415"(response to water)|go:"GO:0016987"(sigma factor activity)|rcsb pdb:5UH5|rcsb pdb:5UH6|rcsb pdb:5UH8|rcsb pdb:5UH9|rcsb pdb:5UHA|rcsb pdb:5UHB|rcsb pdb:5UHC|rcsb pdb:5UHD|rcsb pdb:5UHE|rcsb pdb:5UHF|rcsb pdb:5UHG|rcsb pdb:6EDT|rcsb pdb:6EE8|rcsb pdb:6EEC|rcsb pdb:6M7J|rcsb pdb:6VVX|rcsb pdb:6VVY|rcsb pdb:6VVZ|rcsb pdb:6VW0|interpro:IPR036388|rcsb pdb:6BZO|rcsb pdb:6C04|rcsb pdb:6C05|rcsb pdb:6C06|rcsb pdb:6ONO|rcsb pdb:6ONU	-	crc64:15F27E0732FD6AD7	-	figure legend:Fig 1, Extended Data Fig 2, 3, Extended Data Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2020/01/10	2020/03/13	rogid:v2h+wJJmq9HObjLJEmmAcQjWdKg83332	rogid:3bIMn83egtebfdtsQKnF7c67eMY83332	rigid:VcCwdmSYyU+WQQQHcsvPwlpQACE	false	-	-	1	1	psi-mi:"MI:0396"(predetermined participant)|psi-mi:"MI:2287"(identification by structure determination)	psi-mi:"MI:0396"(predetermined participant)|psi-mi:"MI:2287"(identification by structure determination)
uniprotkb:P9WJG3	uniprotkb:V9Z879	intact:EBI-6421028|uniprotkb:O53568|uniprotkb:F2GJS9|uniprotkb:Q7D585|uniprotkb:L0TFY0	intact:EBI-25469999|ensemblbacteria:SGM05157	psi-mi:card_myctu(display_long)|uniprotkb:carD(gene name)|psi-mi:carD(display_short)|uniprotkb:Rv3583c(locus name)	psi-mi:v9z879_myctx(display_long)|uniprotkb:rpoB(gene name)|psi-mi:rpoB(display_short)|uniprotkb:RNA polymerase subunit beta(gene name synonym)|uniprotkb:Transcriptase subunit beta(gene name synonym)|uniprotkb:ERS013440_02644(orf name)|uniprotkb:FPJ64_03615(orf name)|uniprotkb:FPJ79_03620(orf name)|uniprotkb:FPJ89_03605(orf name)|uniprotkb:FPJ91_03625(orf name)|uniprotkb:FPJ93_03620(orf name)|uniprotkb:FPJ95_03610(orf name)|uniprotkb:FPJ98_03615(orf name)|uniprotkb:FPJ99_03610(orf name)|uniprotkb:FPK00_03605(orf name)|uniprotkb:FPK01_03640(orf name)|uniprotkb:FPK06_03610(orf name)|uniprotkb:FPK07_03610(orf name)|uniprotkb:FPK08_03620(orf name)|uniprotkb:FPK09_03615(orf name)|uniprotkb:FPK11_03615(orf name)|uniprotkb:FPK12_03575(orf name)|uniprotkb:FPK13_03610(orf name)|uniprotkb:FPK14_03610(orf name)|uniprotkb:FPK16_03610(orf name)|uniprotkb:FPK17_03610(orf name)|uniprotkb:FPK18_03615(orf name)|uniprotkb:FPK21_03585(orf name)	psi-mi:"MI:0410"(3D electron microscopy)	Boyaci et al. (2019)	imex:IM-27849|pubmed:30626968	taxid:83332(myctu)|taxid:83332("Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)")	taxid:1773(myctx)|taxid:1773(Mycobacterium tuberculosis)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0465"(DIP)	intact:EBI-25396352|emdb:EMD-9041|wwpdb:6EDT|emdb:EMD-9037|wwpdb:6EE8|emdb:EMD-9039|wwpdb:6EEC|imex:IM-27849-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	rcsb pdb:4ILU|rcsb pdb:4MFR|go:"GO:0015968"(stringent response)|go:"GO:0040009"(regulation of growth rate)|rcsb pdb:4KMC|rcsb pdb:6VVX|rcsb pdb:6VVY|rcsb pdb:6VVZ|rcsb pdb:6VW0|refseq:WP_003419482.1|interpro:IPR003711(Transcription factor CarD)|refseq:NP_218100.1|rcsb pdb:4KBM|interpro:IPR042215|rcsb pdb:6EDT|rcsb pdb:6EE8|rcsb pdb:6EEC|interpro:IPR036101	ensemblbacteria:SAMEA2682864_01701(gene)|ensemblbacteria:SGM05157(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0003899"(DNA-directed 5'-3' RNA polymerase activity)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0032549"(ribonucleoside binding)|refseq:WP_003900992.1|interpro:IPR042107|interpro:IPR019462|interpro:IPR015712(DNA-directed RNA polymerase, subunit 2)|interpro:IPR007120(DNA-directed RNA polymerase, subunit 2, domain 6)|interpro:IPR037033|interpro:IPR010243(DNA-directed RNA polymerase, beta subunit, bacterial-type)|interpro:IPR007121(RNA polymerase, beta subunit, conserved site)|interpro:IPR007644(RNA polymerase, beta subunit, protrusion)|interpro:IPR007642(RNA polymerase Rpb2, domain 2)|interpro:IPR037034|interpro:IPR007645(RNA polymerase Rpb2, domain 3)|interpro:IPR007641(RNA polymerase Rpb2, domain 7)|interpro:IPR014724(RNA polymerase Rpb2, OB-fold)	-	crc64:15F27E0732FD6AD7	-	figure legend:Fig 1, Extended Data Fig 2, 3, Extended Data Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2020/01/10	2020/03/13	rogid:v2h+wJJmq9HObjLJEmmAcQjWdKg83332	rogid:MYJ7YjrdScWHh7nmvSzkGXoI3881773	rigid:VcCwdmSYyU+WQQQHcsvPwlpQACE	false	-	-	1	1	psi-mi:"MI:0396"(predetermined participant)|psi-mi:"MI:2287"(identification by structure determination)	psi-mi:"MI:0396"(predetermined participant)|psi-mi:"MI:2287"(identification by structure determination)
uniprotkb:P9WHJ5	uniprotkb:A5U8D3	intact:EBI-25396356|uniprotkb:L7N5Z6	intact:EBI-25396525|ensemblbacteria:ABQ75283	psi-mi:rbpa_myctu(display_long)|uniprotkb:rbpA(gene name)|psi-mi:rbpA(display_short)|uniprotkb:Rv2050(locus name)	psi-mi:rpoa_mycta(display_long)|uniprotkb:RNA polymerase subunit alpha(gene name synonym)|uniprotkb:Transcriptase subunit alpha(gene name synonym)|uniprotkb:MRA_3498(locus name)|uniprotkb:rpoA(gene name)|psi-mi:rpoA(display_short)	psi-mi:"MI:0410"(3D electron microscopy)	Boyaci et al. (2019)	imex:IM-27849|pubmed:30626968	taxid:83332(myctu)|taxid:83332("Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)")	taxid:419947(strain atcc 25177 /)|taxid:419947(Mycobacterium tuberculosis)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0465"(DIP)	intact:EBI-25396501|wwpdb:6M7J|emdb:EMD-9047|imex:IM-27849-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	go:"GO:0001000"(bacterial-type RNA polymerase core enzyme binding)|go:"GO:0001108"(bacterial-type RNA polymerase holo enzyme binding)|go:"GO:0005618"(cell wall)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|refseq:NP_216566.1|refseq:WP_003410601.1|rcsb pdb:2M4V|rcsb pdb:2M6P|rcsb pdb:4X8K|rcsb pdb:6BZO|rcsb pdb:6C04|rcsb pdb:6C05|rcsb pdb:6C06|rcsb pdb:6EDT|rcsb pdb:6EE8|rcsb pdb:6EEC|rcsb pdb:6M7J|interpro:IPR038638|interpro:IPR025182|rcsb pdb:6VVX|rcsb pdb:6VVY|rcsb pdb:6VVZ|rcsb pdb:6VW0	refseq:WP_003418351.1|interpro:IPR011262(DNA-directed RNA polymerase, insert)|interpro:IPR011263(DNA-directed RNA polymerase, RpoA/D/Rpb3-type)|interpro:IPR011773(DNA-directed RNA polymerase, alpha subunit)|interpro:IPR036603|interpro:IPR011260(RNA polymerase, alpha subunit, C-terminal)|interpro:IPR036643|ensemblbacteria:ABQ75283(transcript)|ensemblbacteria:MRA_3498(gene)|go:"GO:0003677"(DNA binding)|go:"GO:0003899"(DNA-directed 5'-3' RNA polymerase activity)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0046983"(protein dimerization activity)	-	-	-	figure legend:Fig 1, Extended Data Fig 2, 3, 5, Extended Data Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2020/01/10	2020/03/13	rogid:m2PqpKD1I/Rc/KsveEm4GTXeoU083332	rogid:LTBkYO0JRDnFzCI5CB7/T6ZQ+LQ419947	rigid:usbcdRFUOd1qqNqZoRFIAtNyGx4	false	-	-	1	1	psi-mi:"MI:0396"(predetermined participant)|psi-mi:"MI:2287"(identification by structure determination)	psi-mi:"MI:0396"(predetermined participant)|psi-mi:"MI:2287"(identification by structure determination)
uniprotkb:P9WHJ5	uniprotkb:P9WGY7	intact:EBI-25396356|uniprotkb:L7N5Z6	intact:EBI-6429487|uniprotkb:P0A674|uniprotkb:O06771|uniprotkb:P47769|uniprotkb:L0T4I2	psi-mi:rbpa_myctu(display_long)|uniprotkb:rbpA(gene name)|psi-mi:rbpA(display_short)|uniprotkb:Rv2050(locus name)	psi-mi:rpoc_myctu(display_long)|uniprotkb:rpoC(gene name)|psi-mi:rpoC(display_short)|uniprotkb:RNA polymerase subunit beta'(gene name synonym)|uniprotkb:Transcriptase subunit beta'(gene name synonym)|uniprotkb:MTCI376.07c(orf name)|uniprotkb:Rv0668(locus name)	psi-mi:"MI:0410"(3D electron microscopy)	Boyaci et al. (2019)	imex:IM-27849|pubmed:30626968	taxid:83332(myctu)|taxid:83332("Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)")	taxid:83332(myctu)|taxid:83332("Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)")	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0465"(DIP)	intact:EBI-25396501|wwpdb:6M7J|emdb:EMD-9047|imex:IM-27849-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	go:"GO:0001000"(bacterial-type RNA polymerase core enzyme binding)|go:"GO:0001108"(bacterial-type RNA polymerase holo enzyme binding)|go:"GO:0005618"(cell wall)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|refseq:NP_216566.1|refseq:WP_003410601.1|rcsb pdb:2M4V|rcsb pdb:2M6P|rcsb pdb:4X8K|rcsb pdb:6BZO|rcsb pdb:6C04|rcsb pdb:6C05|rcsb pdb:6C06|rcsb pdb:6EDT|rcsb pdb:6EE8|rcsb pdb:6EEC|rcsb pdb:6M7J|interpro:IPR038638|interpro:IPR025182|rcsb pdb:6VVX|rcsb pdb:6VVY|rcsb pdb:6VVZ|rcsb pdb:6VW0	rcsb pdb:6BZO|rcsb pdb:6C04|rcsb pdb:6C05|rcsb pdb:6TYE|go:"GO:0000287"(magnesium ion binding)|go:"GO:0003677"(DNA binding)|go:"GO:0003899"(DNA-directed 5'-3' RNA polymerase activity)|go:"GO:0005618"(cell wall)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0008270"(zinc ion binding)|rcsb pdb:6C06|rcsb pdb:6VVX|rcsb pdb:6VVY|rcsb pdb:6VVZ|rcsb pdb:6VW0|rcsb pdb:6FBV|refseq:WP_003403413.1|rcsb pdb:6TYF|rcsb pdb:6TYG|refseq:NP_215182.1|interpro:IPR012754(DNA-directed RNA polymerase, subunit beta-prime)|interpro:IPR000722(RNA polymerase, alpha subunit)|interpro:IPR006592(RNA polymerase, N-terminal)|interpro:IPR007080(RNA polymerase Rpb1, domain 1)|interpro:IPR007066(RNA polymerase Rpb1, domain 3)|interpro:IPR007083(RNA polymerase Rpb1, domain 4)|interpro:IPR007081(RNA polymerase Rpb1, domain 5)|rcsb pdb:5UH5|rcsb pdb:5UH6|rcsb pdb:5UH7|rcsb pdb:5UH8|rcsb pdb:5UH9|rcsb pdb:5UHA|rcsb pdb:5UHB|rcsb pdb:5UHC|rcsb pdb:5UHD|rcsb pdb:5UHE|rcsb pdb:5UHF|rcsb pdb:5UHG|rcsb pdb:5ZX2|rcsb pdb:5ZX3|rcsb pdb:6EDT|rcsb pdb:6EE8|rcsb pdb:6EEC|rcsb pdb:6M7J|interpro:IPR038120|rcsb pdb:6JCX|rcsb pdb:6JCY|interpro:IPR042102|rcsb pdb:6DV9|rcsb pdb:6DVB|rcsb pdb:6DVC|rcsb pdb:6DVD|rcsb pdb:6DVE|reactome:R-HSA-9639775|rcsb pdb:6KON|rcsb pdb:6KOO|rcsb pdb:6KOP|rcsb pdb:6KOQ	-	-	-	figure legend:Fig 1, Extended Data Fig 2, 3, 5, Extended Data Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2020/01/10	2020/03/13	rogid:m2PqpKD1I/Rc/KsveEm4GTXeoU083332	rogid:QoDUBgmHeTU4+HwWBYkj21i1Doc83332	rigid:usbcdRFUOd1qqNqZoRFIAtNyGx4	false	-	-	1	1	psi-mi:"MI:0396"(predetermined participant)|psi-mi:"MI:2287"(identification by structure determination)	psi-mi:"MI:0396"(predetermined participant)|psi-mi:"MI:2287"(identification by structure determination)
uniprotkb:P9WHJ5	uniprotkb:P9WGY5	intact:EBI-25396356|uniprotkb:L7N5Z6	intact:EBI-6429563|uniprotkb:P66721|uniprotkb:P71660|uniprotkb:L0T993	psi-mi:rbpa_myctu(display_long)|uniprotkb:rbpA(gene name)|psi-mi:rbpA(display_short)|uniprotkb:Rv2050(locus name)	psi-mi:rpoz_myctu(display_long)|uniprotkb:rpoZ(gene name)|psi-mi:rpoZ(display_short)|uniprotkb:RNA polymerase omega subunit(gene name synonym)|uniprotkb:Transcriptase subunit omega(gene name synonym)|uniprotkb:MTCY21B4.07(orf name)|uniprotkb:Rv1390(locus name)	psi-mi:"MI:0410"(3D electron microscopy)	Boyaci et al. (2019)	imex:IM-27849|pubmed:30626968	taxid:83332(myctu)|taxid:83332("Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)")	taxid:83332(myctu)|taxid:83332("Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)")	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0465"(DIP)	intact:EBI-25396501|wwpdb:6M7J|emdb:EMD-9047|imex:IM-27849-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	go:"GO:0001000"(bacterial-type RNA polymerase core enzyme binding)|go:"GO:0001108"(bacterial-type RNA polymerase holo enzyme binding)|go:"GO:0005618"(cell wall)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|refseq:NP_216566.1|refseq:WP_003410601.1|rcsb pdb:2M4V|rcsb pdb:2M6P|rcsb pdb:4X8K|rcsb pdb:6BZO|rcsb pdb:6C04|rcsb pdb:6C05|rcsb pdb:6C06|rcsb pdb:6EDT|rcsb pdb:6EE8|rcsb pdb:6EEC|rcsb pdb:6M7J|interpro:IPR038638|interpro:IPR025182|rcsb pdb:6VVX|rcsb pdb:6VVY|rcsb pdb:6VVZ|rcsb pdb:6VW0	rcsb pdb:6BZO|rcsb pdb:6C04|rcsb pdb:6C05|rcsb pdb:6C06|go:"GO:0003677"(DNA binding)|go:"GO:0003899"(DNA-directed 5'-3' RNA polymerase activity)|go:"GO:0005618"(cell wall)|go:"GO:0005829"(cytosol)|go:"GO:0006351"(transcription, DNA-templated)|rcsb pdb:6VVX|rcsb pdb:6VVY|rcsb pdb:6VVZ|rcsb pdb:6VW0|rcsb pdb:6FBV|refseq:WP_003407248.1|refseq:NP_215906.1|interpro:IPR003716(RNA polymerase, omega subunit)|interpro:IPR006110(RNA polymerase Rpb6)|interpro:IPR012293(RNA polymerase subunit, RPB6/omega)|rcsb pdb:6TYE|rcsb pdb:6TYF|rcsb pdb:6TYG|rcsb pdb:5UH5|rcsb pdb:5UH6|rcsb pdb:5UH8|rcsb pdb:5UH9|rcsb pdb:5UHA|rcsb pdb:5UHB|rcsb pdb:5UHC|rcsb pdb:5UHD|rcsb pdb:5UHE|rcsb pdb:5UHF|rcsb pdb:5UHG|rcsb pdb:5ZX2|rcsb pdb:5ZX3|rcsb pdb:6EDT|rcsb pdb:6EE8|rcsb pdb:6EEC|rcsb pdb:6M7J|interpro:IPR036161|rcsb pdb:6JCX|rcsb pdb:6JCY|rcsb pdb:6DV9|rcsb pdb:6DVB|rcsb pdb:6DVC|rcsb pdb:6DVD|rcsb pdb:6DVE|reactome:R-HSA-9639775|rcsb pdb:6KON|rcsb pdb:6KOO|rcsb pdb:6KOP|rcsb pdb:6KOQ	-	-	-	figure legend:Fig 1, Extended Data Fig 2, 3, 5, Extended Data Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2020/01/10	2020/03/13	rogid:m2PqpKD1I/Rc/KsveEm4GTXeoU083332	rogid:vGl8przz7lgqXNpNmTl5lvScP2o83332	rigid:usbcdRFUOd1qqNqZoRFIAtNyGx4	false	-	-	1	1	psi-mi:"MI:0396"(predetermined participant)|psi-mi:"MI:2287"(identification by structure determination)	psi-mi:"MI:0396"(predetermined participant)|psi-mi:"MI:2287"(identification by structure determination)
uniprotkb:P9WHJ5	uniprotkb:P9WGI1	intact:EBI-25396356|uniprotkb:L7N5Z6	intact:EBI-11859464|uniprotkb:L0TAM5|uniprotkb:O08495|uniprotkb:O08513|uniprotkb:P0A602|uniprotkb:Q60162	psi-mi:rbpa_myctu(display_long)|uniprotkb:rbpA(gene name)|psi-mi:rbpA(display_short)|uniprotkb:Rv2050(locus name)	psi-mi:siga_myctu(display_long)|uniprotkb:sigA(gene name)|psi-mi:sigA(display_short)|uniprotkb:mysA(gene name synonym)|uniprotkb:rpoD(gene name synonym)|uniprotkb:rpoV(gene name synonym)|uniprotkb:MTCY05A6.24(orf name)|uniprotkb:Rv2703(locus name)	psi-mi:"MI:0410"(3D electron microscopy)	Boyaci et al. (2019)	imex:IM-27849|pubmed:30626968	taxid:83332(myctu)|taxid:83332("Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)")	taxid:83332(myctu)|taxid:83332("Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)")	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0465"(DIP)	intact:EBI-25396501|wwpdb:6M7J|emdb:EMD-9047|imex:IM-27849-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	go:"GO:0001000"(bacterial-type RNA polymerase core enzyme binding)|go:"GO:0001108"(bacterial-type RNA polymerase holo enzyme binding)|go:"GO:0005618"(cell wall)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|refseq:NP_216566.1|refseq:WP_003410601.1|rcsb pdb:2M4V|rcsb pdb:2M6P|rcsb pdb:4X8K|rcsb pdb:6BZO|rcsb pdb:6C04|rcsb pdb:6C05|rcsb pdb:6C06|rcsb pdb:6EDT|rcsb pdb:6EE8|rcsb pdb:6EEC|rcsb pdb:6M7J|interpro:IPR038638|interpro:IPR025182|rcsb pdb:6VVX|rcsb pdb:6VVY|rcsb pdb:6VVZ|rcsb pdb:6VW0	refseq:NP_217219.1|refseq:WP_003413944.1|rcsb pdb:4X8K|interpro:IPR014284(RNA polymerase sigma-70)|interpro:IPR000943(RNA polymerase sigma-70 factor)|interpro:IPR009042(RNA polymerase sigma-70 region 1.2)|interpro:IPR007627(RNA polymerase sigma-70 region 2)|interpro:IPR007624(RNA polymerase sigma-70 region 3)|interpro:IPR007630(RNA polymerase sigma-70 region 4)|interpro:IPR013325(RNA polymerase sigma factor, region 2)|interpro:IPR013324(RNA polymerase sigma factor, regions 3 and 4)|interpro:IPR012760(RNA polymerase sigma factor RpoD, C-terminal)|interpro:IPR028630|rcsb pdb:6FBV|go:"GO:0001123"|go:"GO:0003677"(DNA binding)|go:"GO:0005618"(cell wall)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0009415"(response to water)|go:"GO:0016987"(sigma factor activity)|rcsb pdb:5UH5|rcsb pdb:5UH6|rcsb pdb:5UH8|rcsb pdb:5UH9|rcsb pdb:5UHA|rcsb pdb:5UHB|rcsb pdb:5UHC|rcsb pdb:5UHD|rcsb pdb:5UHE|rcsb pdb:5UHF|rcsb pdb:5UHG|rcsb pdb:6EDT|rcsb pdb:6EE8|rcsb pdb:6EEC|rcsb pdb:6M7J|rcsb pdb:6VVX|rcsb pdb:6VVY|rcsb pdb:6VVZ|rcsb pdb:6VW0|interpro:IPR036388|rcsb pdb:6BZO|rcsb pdb:6C04|rcsb pdb:6C05|rcsb pdb:6C06|rcsb pdb:6ONO|rcsb pdb:6ONU	-	-	-	figure legend:Fig 1, Extended Data Fig 2, 3, 5, Extended Data Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2020/01/10	2020/03/13	rogid:m2PqpKD1I/Rc/KsveEm4GTXeoU083332	rogid:3bIMn83egtebfdtsQKnF7c67eMY83332	rigid:usbcdRFUOd1qqNqZoRFIAtNyGx4	false	-	-	1	1	psi-mi:"MI:0396"(predetermined participant)|psi-mi:"MI:2287"(identification by structure determination)	psi-mi:"MI:0396"(predetermined participant)|psi-mi:"MI:2287"(identification by structure determination)
uniprotkb:P9WHJ5	uniprotkb:V9Z879	intact:EBI-25396356|uniprotkb:L7N5Z6	intact:EBI-25469999|ensemblbacteria:SGM05157	psi-mi:rbpa_myctu(display_long)|uniprotkb:rbpA(gene name)|psi-mi:rbpA(display_short)|uniprotkb:Rv2050(locus name)	psi-mi:v9z879_myctx(display_long)|uniprotkb:rpoB(gene name)|psi-mi:rpoB(display_short)|uniprotkb:RNA polymerase subunit beta(gene name synonym)|uniprotkb:Transcriptase subunit beta(gene name synonym)|uniprotkb:ERS013440_02644(orf name)|uniprotkb:FPJ64_03615(orf name)|uniprotkb:FPJ79_03620(orf name)|uniprotkb:FPJ89_03605(orf name)|uniprotkb:FPJ91_03625(orf name)|uniprotkb:FPJ93_03620(orf name)|uniprotkb:FPJ95_03610(orf name)|uniprotkb:FPJ98_03615(orf name)|uniprotkb:FPJ99_03610(orf name)|uniprotkb:FPK00_03605(orf name)|uniprotkb:FPK01_03640(orf name)|uniprotkb:FPK06_03610(orf name)|uniprotkb:FPK07_03610(orf name)|uniprotkb:FPK08_03620(orf name)|uniprotkb:FPK09_03615(orf name)|uniprotkb:FPK11_03615(orf name)|uniprotkb:FPK12_03575(orf name)|uniprotkb:FPK13_03610(orf name)|uniprotkb:FPK14_03610(orf name)|uniprotkb:FPK16_03610(orf name)|uniprotkb:FPK17_03610(orf name)|uniprotkb:FPK18_03615(orf name)|uniprotkb:FPK21_03585(orf name)	psi-mi:"MI:0410"(3D electron microscopy)	Boyaci et al. (2019)	imex:IM-27849|pubmed:30626968	taxid:83332(myctu)|taxid:83332("Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)")	taxid:1773(myctx)|taxid:1773(Mycobacterium tuberculosis)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0465"(DIP)	intact:EBI-25396501|wwpdb:6M7J|emdb:EMD-9047|imex:IM-27849-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	go:"GO:0001000"(bacterial-type RNA polymerase core enzyme binding)|go:"GO:0001108"(bacterial-type RNA polymerase holo enzyme binding)|go:"GO:0005618"(cell wall)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|refseq:NP_216566.1|refseq:WP_003410601.1|rcsb pdb:2M4V|rcsb pdb:2M6P|rcsb pdb:4X8K|rcsb pdb:6BZO|rcsb pdb:6C04|rcsb pdb:6C05|rcsb pdb:6C06|rcsb pdb:6EDT|rcsb pdb:6EE8|rcsb pdb:6EEC|rcsb pdb:6M7J|interpro:IPR038638|interpro:IPR025182|rcsb pdb:6VVX|rcsb pdb:6VVY|rcsb pdb:6VVZ|rcsb pdb:6VW0	ensemblbacteria:SAMEA2682864_01701(gene)|ensemblbacteria:SGM05157(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0003899"(DNA-directed 5'-3' RNA polymerase activity)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0032549"(ribonucleoside binding)|refseq:WP_003900992.1|interpro:IPR042107|interpro:IPR019462|interpro:IPR015712(DNA-directed RNA polymerase, subunit 2)|interpro:IPR007120(DNA-directed RNA polymerase, subunit 2, domain 6)|interpro:IPR037033|interpro:IPR010243(DNA-directed RNA polymerase, beta subunit, bacterial-type)|interpro:IPR007121(RNA polymerase, beta subunit, conserved site)|interpro:IPR007644(RNA polymerase, beta subunit, protrusion)|interpro:IPR007642(RNA polymerase Rpb2, domain 2)|interpro:IPR037034|interpro:IPR007645(RNA polymerase Rpb2, domain 3)|interpro:IPR007641(RNA polymerase Rpb2, domain 7)|interpro:IPR014724(RNA polymerase Rpb2, OB-fold)	-	-	-	figure legend:Fig 1, Extended Data Fig 2, 3, 5, Extended Data Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2020/01/10	2020/03/13	rogid:m2PqpKD1I/Rc/KsveEm4GTXeoU083332	rogid:MYJ7YjrdScWHh7nmvSzkGXoI3881773	rigid:usbcdRFUOd1qqNqZoRFIAtNyGx4	false	-	-	1	1	psi-mi:"MI:0396"(predetermined participant)|psi-mi:"MI:2287"(identification by structure determination)	psi-mi:"MI:0396"(predetermined participant)|psi-mi:"MI:2287"(identification by structure determination)