#ID(s) interactor A ID(s) interactor B Alt. ID(s) interactor A Alt. ID(s) interactor B Alias(es) interactor A Alias(es) interactor B Interaction detection method(s) Publication 1st author(s) Publication Identifier(s) Taxid interactor A Taxid interactor B Interaction type(s) Source database(s) Interaction identifier(s) Confidence value(s) Expansion method(s) Biological role(s) interactor A Biological role(s) interactor B Experimental role(s) interactor A Experimental role(s) interactor B Type(s) interactor A Type(s) interactor B Xref(s) interactor A Xref(s) interactor B Interaction Xref(s) Annotation(s) interactor A Annotation(s) interactor B Interaction annotation(s) Host organism(s) Interaction parameter(s) Creation date Update date Checksum(s) interactor A Checksum(s) interactor B Interaction Checksum(s) Negative Feature(s) interactor A Feature(s) interactor B Stoichiometry(s) interactor A Stoichiometry(s) interactor B Identification method participant A Identification method participant B uniprotkb:P04135 uniprotkb:A0A4X1TRK4 intact:EBI-25568430 intact:EBI-25568444|ensembl:ENSSSCP00070018912 psi-mi:vme1_cvppu(display_long)|uniprotkb:M(gene name)|psi-mi:M(display_short)|uniprotkb:E1 glycoprotein(gene name synonym)|uniprotkb:Matrix glycoprotein(gene name synonym)|uniprotkb:Membrane glycoprotein(gene name synonym)|uniprotkb:5(orf name) psi-mi:a0a4x1trk4_pig(display_long)|uniprotkb:Multifunctional protein ADE2(gene name synonym)|uniprotkb:Phosphoribosylaminoimidazole carboxylase(gene name synonym)|uniprotkb:Phosphoribosylaminoimidazole-succinocarboxamide synthase(gene name synonym)|uniprotkb:SAICAR synthetase(gene name synonym) psi-mi:"MI:0018"(two hybrid) Song et al. (2019) pubmed:30583231|imex:IM-27937 taxid:11151(TGEV)|taxid:11151("Porcine transmissible gastroenteritis coronavirus (strain Purdue)") taxid:9823(pig)|taxid:9823("Sus scrofa (Pig)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-25568427|imex:IM-27937-1 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0016021"(integral component of membrane)|go:"GO:0019031"(viral envelope)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039660"(structural constituent of virion)|go:"GO:0044178"(host cell Golgi membrane)|go:"GO:0055036"(virion membrane)|interpro:IPR042551|interpro:IPR002574(Coronavirus M matrix/glycoprotein) ensembl:ENSSSCG00070011686(gene)|ensembl:ENSSSCT00070022867(transcript)|go:"GO:0004638"(phosphoribosylaminoimidazole carboxylase activity)|go:"GO:0004639"(phosphoribosylaminoimidazolesuccinocarboxamide synthase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0006189"('de novo' IMP biosynthetic process)|go:"GO:0043727"(5-amino-4-imidazole carboxylate lyase activity)|interpro:IPR000031("1-(5-Phosphoribosyl)-5-amino-4-imidazole-carboxylate (AIR) carboxylase")|interpro:IPR018236|interpro:IPR028923|interpro:IPR033626|refseq:XP_003129072.1 - - - figure legend:Fig. 1 and Table 2|dataset:Virus - Publications including interactions involving viral proteins|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2020/04/22 2020/04/22 rogid:bmxnB31iav9Xj8ukfXJ5ATMHNd411151 rogid:s5lIIn00/L4fZzhfmMhOnCZ1Xjs9823 rigid:N+q4/u06w2LwbH8g9CkKHd+ydhM false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:P04135 uniprotkb:A0A4X1V3C3 intact:EBI-25568430 intact:EBI-25568497|ensembl:ENSSSCP00070035642 psi-mi:vme1_cvppu(display_long)|uniprotkb:M(gene name)|psi-mi:M(display_short)|uniprotkb:E1 glycoprotein(gene name synonym)|uniprotkb:Matrix glycoprotein(gene name synonym)|uniprotkb:Membrane glycoprotein(gene name synonym)|uniprotkb:5(orf name) psi-mi:a0a4x1v3c3_pig(display_long)|uniprotkb:SNRPD3(gene name)|psi-mi:SNRPD3(display_short)|uniprotkb:snRNP core protein D3(gene name synonym) psi-mi:"MI:0018"(two hybrid) Song et al. (2019) pubmed:30583231|imex:IM-27937 taxid:11151(TGEV)|taxid:11151("Porcine transmissible gastroenteritis coronavirus (strain Purdue)") taxid:9823(pig)|taxid:9823("Sus scrofa (Pig)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-25568493|imex:IM-27937-3 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0016021"(integral component of membrane)|go:"GO:0019031"(viral envelope)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039660"(structural constituent of virion)|go:"GO:0044178"(host cell Golgi membrane)|go:"GO:0055036"(virion membrane)|interpro:IPR042551|interpro:IPR002574(Coronavirus M matrix/glycoprotein) interpro:IPR001163(Like-Sm ribonucleoprotein, core)|interpro:IPR010920(Like-Sm ribonucleoprotein-related, core)|interpro:IPR027141|interpro:IPR034099|ensembl:ENSSSCG00070021329(gene)|ensembl:ENSSSCT00070042392(transcript)|go:"GO:0000387"(spliceosomal snRNP assembly)|go:"GO:0005681"(spliceosomal complex)|go:"GO:0005829"(cytosol)|refseq:NP_001230355.1|refseq:XP_005670932.1|refseq:XP_013838560.1 - - - figure legend:Fig. 1 and Table 2|dataset:Virus - Publications including interactions involving viral proteins|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2020/04/22 2020/04/22 rogid:bmxnB31iav9Xj8ukfXJ5ATMHNd411151 rogid:WkrSZVfVmSQrJYfy7mwp48xjsVA9823 rigid:KVx298Ndb1QXqmNFtiBy15gGM9Q false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:P04135 uniprotkb:F1S215 intact:EBI-25568430 intact:EBI-25568518|ensembl:ENSSSCP00000006754 psi-mi:vme1_cvppu(display_long)|uniprotkb:M(gene name)|psi-mi:M(display_short)|uniprotkb:E1 glycoprotein(gene name synonym)|uniprotkb:Matrix glycoprotein(gene name synonym)|uniprotkb:Membrane glycoprotein(gene name synonym)|uniprotkb:5(orf name) psi-mi:f1s215_pig(display_long)|uniprotkb:RGS4(gene name)|psi-mi:RGS4(display_short) psi-mi:"MI:0018"(two hybrid) Song et al. (2019) pubmed:30583231|imex:IM-27937 taxid:11151(TGEV)|taxid:11151("Porcine transmissible gastroenteritis coronavirus (strain Purdue)") taxid:9823(pig)|taxid:9823("Sus scrofa (Pig)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-25568514|imex:IM-27937-5 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0016021"(integral component of membrane)|go:"GO:0019031"(viral envelope)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039660"(structural constituent of virion)|go:"GO:0044178"(host cell Golgi membrane)|go:"GO:0055036"(virion membrane)|interpro:IPR042551|interpro:IPR002574(Coronavirus M matrix/glycoprotein) interpro:IPR034952|interpro:IPR034953|interpro:IPR036305|reactome:R-SSC-416476|reactome:R-SSC-418594|ensembl:ENSSSCG00000006335(gene)|ensembl:ENSSSCT00000006943(transcript)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|interpro:IPR016137(Regulator of G protein signalling superfamily)|interpro:IPR024066 - - - figure legend:Fig. 1 and Table 2|dataset:Virus - Publications including interactions involving viral proteins|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2020/04/22 2020/04/22 rogid:bmxnB31iav9Xj8ukfXJ5ATMHNd411151 rogid:P4xIQUS80SMVLLE0PoIptbwZujI9823 rigid:sA/vBGMgYREA+UKxqUtpycT/BnM false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:P04135 uniprotkb:F1RNN5 intact:EBI-25568430 intact:EBI-25568542|ensembl:ENSSSCP00000010480 psi-mi:vme1_cvppu(display_long)|uniprotkb:M(gene name)|psi-mi:M(display_short)|uniprotkb:E1 glycoprotein(gene name synonym)|uniprotkb:Matrix glycoprotein(gene name synonym)|uniprotkb:Membrane glycoprotein(gene name synonym)|uniprotkb:5(orf name) psi-mi:f1rnn5_pig(display_long)|uniprotkb:P2RX7(gene name)|psi-mi:P2RX7(display_short) psi-mi:"MI:0018"(two hybrid) Song et al. (2019) pubmed:30583231|imex:IM-27937 taxid:11151(TGEV)|taxid:11151("Porcine transmissible gastroenteritis coronavirus (strain Purdue)") taxid:9823(pig)|taxid:9823("Sus scrofa (Pig)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-25568536|imex:IM-27937-7 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0016021"(integral component of membrane)|go:"GO:0019031"(viral envelope)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039660"(structural constituent of virion)|go:"GO:0044178"(host cell Golgi membrane)|go:"GO:0055036"(virion membrane)|interpro:IPR042551|interpro:IPR002574(Coronavirus M matrix/glycoprotein) go:"GO:0032730"(positive regulation of interleukin-1 alpha production)|go:"GO:0032731"(positive regulation of interleukin-1 beta production)|go:"GO:0032496"(response to lipopolysaccharide)|go:"GO:0032755"(positive regulation of interleukin-6 production)|go:"GO:0032963"(collagen metabolic process)|go:"GO:0033198"(response to ATP)|go:"GO:0034405"(response to fluid shear stress)|go:"GO:0034767"(positive regulation of ion transmembrane transport)|go:"GO:0042098"(T cell proliferation)|go:"GO:0042493"|go:"GO:0042802"(identical protein binding)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043029"(T cell homeostasis)|go:"GO:0043132"(NAD transport)|go:"GO:0043409"(negative regulation of MAPK cascade)|go:"GO:0045779"(negative regulation of bone resorption)|go:"GO:0045794"(negative regulation of cell volume)|go:"GO:0045821"(positive regulation of glycolytic process)|go:"GO:0046513"(ceramide biosynthetic process)|go:"GO:0046931"(pore complex assembly)|go:"GO:0048705"(skeletal system morphogenesis)|go:"GO:0048873"(homeostasis of number of cells within a tissue)|go:"GO:0050714"(positive regulation of protein secretion)|go:"GO:0050830"(defense response to Gram-positive bacterium)|go:"GO:0051209"(release of sequestered calcium ion into cytosol)|go:"GO:0051592"(response to calcium ion)|go:"GO:0051602"(response to electrical stimulus)|go:"GO:0051899"(membrane depolarization)|go:"GO:0051901"(positive regulation of mitochondrial depolarization)|go:"GO:0070230"(positive regulation of lymphocyte apoptotic process)|go:"GO:0071359"(cellular response to dsRNA)|go:"GO:0007005"(mitochondrion organization)|go:"GO:0009612"(response to mechanical stimulus)|go:"GO:0009897"(external side of plasma membrane)|go:"GO:0010043"(response to zinc ion)|go:"GO:0010524"(positive regulation of calcium ion transport into cytosol)|go:"GO:0014049"(positive regulation of glutamate secretion)|go:"GO:0014054"(positive regulation of gamma-aminobutyric acid secretion)|go:"GO:0016079"(synaptic vesicle exocytosis)|go:"GO:0016485"(protein processing)|go:"GO:0017121"(plasma membrane phospholipid scrambling)|go:"GO:0019233"(sensory perception of pain)|go:"GO:0030163"(protein catabolic process)|go:"GO:0030501"(positive regulation of bone mineralization)|go:"GO:0031594"(neuromuscular junction)|go:"GO:0031668"(cellular response to extracellular stimulus)|go:"GO:0032060"(bleb assembly)|go:"GO:0032308"(positive regulation of prostaglandin secretion)|go:"GO:0097191"(extrinsic apoptotic signaling pathway)|go:"GO:0098793"(presynapse)|go:"GO:0098794"(postsynapse)|go:"GO:1904172"(positive regulation of bleb assembly)|interpro:IPR001429(P2X purinoreceptor)|interpro:IPR003050(P2X7 purinoceptor)|interpro:IPR027309|reactome:R-SSC-139853|reactome:R-SSC-418346|reactome:R-SSC-844456|go:"GO:0072593"(reactive oxygen species metabolic process)|ensembl:ENSSSCG00000009817(gene)|ensembl:ENSSSCT00000010760(transcript)|go:"GO:0000187"(obsolete activation of MAPK activity)|go:"GO:0000902"(cell morphogenesis)|go:"GO:0001530"(lipopolysaccharide binding)|go:"GO:0001614"(purinergic nucleotide receptor activity)|go:"GO:0001845"(phagolysosome assembly)|go:"GO:0001916"(positive regulation of T cell mediated cytotoxicity)|go:"GO:0004931"(extracellularly ATP-gated cation channel activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005639"(integral component of nuclear inner membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0006509"(membrane protein ectodomain proteolysis)|go:"GO:0006649"(phospholipid transfer to membrane)|go:"GO:0006900"(vesicle budding from membrane)|go:"GO:0006954"(inflammatory response)|refseq:XP_001926839.2 - - - figure legend:Fig. 1 and Table 2|dataset:Virus - Publications including interactions involving viral proteins|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2020/04/22 2020/04/22 rogid:bmxnB31iav9Xj8ukfXJ5ATMHNd411151 rogid:toOnNcx84CZlw1lKcl4NeFNj91s9823 rigid:5bf23DQJIhayB5BjuuKeMoanRBs false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:P04135 uniprotkb:A6M930 intact:EBI-25568430 intact:EBI-25568629 psi-mi:vme1_cvppu(display_long)|uniprotkb:M(gene name)|psi-mi:M(display_short)|uniprotkb:E1 glycoprotein(gene name synonym)|uniprotkb:Matrix glycoprotein(gene name synonym)|uniprotkb:Membrane glycoprotein(gene name synonym)|uniprotkb:5(orf name) psi-mi:a6m930_pig(display_long)|uniprotkb:EIF4A2(gene name)|psi-mi:EIF4A2(display_short) psi-mi:"MI:0018"(two hybrid) Song et al. (2019) pubmed:30583231|imex:IM-27937 taxid:11151(TGEV)|taxid:11151("Porcine transmissible gastroenteritis coronavirus (strain Purdue)") taxid:9823(pig)|taxid:9823("Sus scrofa (Pig)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-25568625|imex:IM-27937-9 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0016021"(integral component of membrane)|go:"GO:0019031"(viral envelope)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039660"(structural constituent of virion)|go:"GO:0044178"(host cell Golgi membrane)|go:"GO:0055036"(virion membrane)|interpro:IPR042551|interpro:IPR002574(Coronavirus M matrix/glycoprotein) go:"GO:0002183"(cytoplasmic translational initiation)|go:"GO:0003724"(RNA helicase activity)|go:"GO:0003743"(translation initiation factor activity)|go:"GO:0005524"(ATP binding)|go:"GO:0016787"(hydrolase activity)|interpro:IPR044728|refseq:NP_001093665.1|interpro:IPR011545(DNA/RNA helicase, DEAD/DEAH box type, N-terminal)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR027417|interpro:IPR000629(RNA helicase, ATP-dependent, DEAD-box, conserved site)|interpro:IPR014014(RNA helicase, DEAD-box type, Q motif) - - - figure legend:Fig. 1 and Table 2|dataset:Virus - Publications including interactions involving viral proteins|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2020/04/22 2020/04/22 rogid:bmxnB31iav9Xj8ukfXJ5ATMHNd411151 rogid:m9i/jWfsbU+6kQvj1h06x31+awg9823 rigid:i26tkKJUZge2vXNxxvwGwMiIJBY false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:P04135 uniprotkb:A6M930 intact:EBI-25568430 intact:EBI-25568629 psi-mi:vme1_cvppu(display_long)|uniprotkb:M(gene name)|psi-mi:M(display_short)|uniprotkb:E1 glycoprotein(gene name synonym)|uniprotkb:Matrix glycoprotein(gene name synonym)|uniprotkb:Membrane glycoprotein(gene name synonym)|uniprotkb:5(orf name) psi-mi:a6m930_pig(display_long)|uniprotkb:EIF4A2(gene name)|psi-mi:EIF4A2(display_short) psi-mi:"MI:0096"(pull down) Song et al. (2019) pubmed:30583231|imex:IM-27937 taxid:11151(TGEV)|taxid:11151("Porcine transmissible gastroenteritis coronavirus (strain Purdue)") taxid:9823(pig)|taxid:9823("Sus scrofa (Pig)") psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0469"(IntAct) intact:EBI-25568686|imex:IM-27937-11 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0016021"(integral component of membrane)|go:"GO:0019031"(viral envelope)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039660"(structural constituent of virion)|go:"GO:0044178"(host cell Golgi membrane)|go:"GO:0055036"(virion membrane)|interpro:IPR042551|interpro:IPR002574(Coronavirus M matrix/glycoprotein) go:"GO:0002183"(cytoplasmic translational initiation)|go:"GO:0003724"(RNA helicase activity)|go:"GO:0003743"(translation initiation factor activity)|go:"GO:0005524"(ATP binding)|go:"GO:0016787"(hydrolase activity)|interpro:IPR044728|refseq:NP_001093665.1|interpro:IPR011545(DNA/RNA helicase, DEAD/DEAH box type, N-terminal)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR027417|interpro:IPR000629(RNA helicase, ATP-dependent, DEAD-box, conserved site)|interpro:IPR014014(RNA helicase, DEAD-box type, Q motif) - - - figure legend:Fig. 3A-B|dataset:Virus - Publications including interactions involving viral proteins|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2020/04/22 2020/04/22 rogid:bmxnB31iav9Xj8ukfXJ5ATMHNd411151 rogid:m9i/jWfsbU+6kQvj1h06x31+awg9823 rigid:i26tkKJUZge2vXNxxvwGwMiIJBY false glutathione s tranferase tag:?-? his tag:?-? - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:P04135 uniprotkb:A6M930 intact:EBI-25568430 intact:EBI-25568629 psi-mi:vme1_cvppu(display_long)|uniprotkb:M(gene name)|psi-mi:M(display_short)|uniprotkb:E1 glycoprotein(gene name synonym)|uniprotkb:Matrix glycoprotein(gene name synonym)|uniprotkb:Membrane glycoprotein(gene name synonym)|uniprotkb:5(orf name) psi-mi:a6m930_pig(display_long)|uniprotkb:EIF4A2(gene name)|psi-mi:EIF4A2(display_short) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Song et al. (2019) pubmed:30583231|imex:IM-27937 taxid:11151(TGEV)|taxid:11151("Porcine transmissible gastroenteritis coronavirus (strain Purdue)") taxid:9823(pig)|taxid:9823("Sus scrofa (Pig)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-25568706|imex:IM-27937-13 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0016021"(integral component of membrane)|go:"GO:0019031"(viral envelope)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039660"(structural constituent of virion)|go:"GO:0044178"(host cell Golgi membrane)|go:"GO:0055036"(virion membrane)|interpro:IPR042551|interpro:IPR002574(Coronavirus M matrix/glycoprotein) go:"GO:0002183"(cytoplasmic translational initiation)|go:"GO:0003724"(RNA helicase activity)|go:"GO:0003743"(translation initiation factor activity)|go:"GO:0005524"(ATP binding)|go:"GO:0016787"(hydrolase activity)|interpro:IPR044728|refseq:NP_001093665.1|interpro:IPR011545(DNA/RNA helicase, DEAD/DEAH box type, N-terminal)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR027417|interpro:IPR000629(RNA helicase, ATP-dependent, DEAD-box, conserved site)|interpro:IPR014014(RNA helicase, DEAD-box type, Q motif) - - - figure legend:Fig. 3C|dataset:Virus - Publications including interactions involving viral proteins|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9834(pig-iec)|taxid:9834(Porcine intestinal epithelial crypt cells) - 2020/04/22 2020/04/22 rogid:bmxnB31iav9Xj8ukfXJ5ATMHNd411151 rogid:m9i/jWfsbU+6kQvj1h06x31+awg9823 rigid:i26tkKJUZge2vXNxxvwGwMiIJBY false - - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:P04135 uniprotkb:A6M930 intact:EBI-25568430 intact:EBI-25568629 psi-mi:vme1_cvppu(display_long)|uniprotkb:M(gene name)|psi-mi:M(display_short)|uniprotkb:E1 glycoprotein(gene name synonym)|uniprotkb:Matrix glycoprotein(gene name synonym)|uniprotkb:Membrane glycoprotein(gene name synonym)|uniprotkb:5(orf name) psi-mi:a6m930_pig(display_long)|uniprotkb:EIF4A2(gene name)|psi-mi:EIF4A2(display_short) psi-mi:"MI:0663"(confocal microscopy) Song et al. (2019) pubmed:30583231|imex:IM-27937 taxid:11151(TGEV)|taxid:11151("Porcine transmissible gastroenteritis coronavirus (strain Purdue)") taxid:9823(pig)|taxid:9823("Sus scrofa (Pig)") psi-mi:"MI:0403"(colocalization) psi-mi:"MI:0469"(IntAct) intact:EBI-25568728|imex:IM-27937-15 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0016021"(integral component of membrane)|go:"GO:0019031"(viral envelope)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0039660"(structural constituent of virion)|go:"GO:0044178"(host cell Golgi membrane)|go:"GO:0055036"(virion membrane)|interpro:IPR042551|interpro:IPR002574(Coronavirus M matrix/glycoprotein) go:"GO:0002183"(cytoplasmic translational initiation)|go:"GO:0003724"(RNA helicase activity)|go:"GO:0003743"(translation initiation factor activity)|go:"GO:0005524"(ATP binding)|go:"GO:0016787"(hydrolase activity)|interpro:IPR044728|refseq:NP_001093665.1|interpro:IPR011545(DNA/RNA helicase, DEAD/DEAH box type, N-terminal)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR027417|interpro:IPR000629(RNA helicase, ATP-dependent, DEAD-box, conserved site)|interpro:IPR014014(RNA helicase, DEAD-box type, Q motif) go:"GO:0005737"(cytoplasm) - - figure legend:Fig. 4|comment:The green fluorescence of M protein and the red fluorescence of EIF4A2 were observed to be partially overlapping in the cytoplasm|dataset:Virus - Publications including interactions involving viral proteins|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9834(pig-iec)|taxid:9834(Porcine intestinal epithelial crypt cells) - 2020/04/22 2020/04/22 rogid:bmxnB31iav9Xj8ukfXJ5ATMHNd411151 rogid:m9i/jWfsbU+6kQvj1h06x31+awg9823 rigid:i26tkKJUZge2vXNxxvwGwMiIJBY false - - - - psi-mi:"MI:0422"(immunostaining) psi-mi:"MI:0422"(immunostaining)