#ID(s) interactor A	ID(s) interactor B	Alt. ID(s) interactor A	Alt. ID(s) interactor B	Alias(es) interactor A	Alias(es) interactor B	Interaction detection method(s)	Publication 1st author(s)	Publication Identifier(s)	Taxid interactor A	Taxid interactor B	Interaction type(s)	Source database(s)	Interaction identifier(s)	Confidence value(s)	Expansion method(s)	Biological role(s) interactor A	Biological role(s) interactor B	Experimental role(s) interactor A	Experimental role(s) interactor B	Type(s) interactor A	Type(s) interactor B	Xref(s) interactor A	Xref(s) interactor B	Interaction Xref(s)	Annotation(s) interactor A	Annotation(s) interactor B	Interaction annotation(s)	Host organism(s)	Interaction parameter(s)	Creation date	Update date	Checksum(s) interactor A	Checksum(s) interactor B	Interaction Checksum(s)	Negative	Feature(s) interactor A	Feature(s) interactor B	Stoichiometry(s) interactor A	Stoichiometry(s) interactor B	Identification method participant A	Identification method participant B
uniprotkb:P9WJD5	uniprotkb:P9WJB9	intact:EBI-26358082|uniprotkb:L0TEQ0|uniprotkb:O06269|uniprotkb:Q7D573	intact:EBI-25767670|uniprotkb:L0TE21|uniprotkb:O69744|uniprotkb:Q7D4P0	psi-mi:espd_myctu(display_long)|uniprotkb:espD(gene name)|psi-mi:espD(display_short)|uniprotkb:snm10(gene name synonym)|uniprotkb:Rv3614c(locus name)	psi-mi:espl_myctu(display_long)|uniprotkb:espL(gene name)|psi-mi:espL(display_short)|uniprotkb:Rv3880c(locus name)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Sala et al. (2018)	pubmed:30571761|imex:IM-28370	taxid:83332(myctu)|taxid:83332("Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)")	taxid:83332(myctu)|taxid:83332("Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)")	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26358098|imex:IM-28370-1	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	go:"GO:0005576"(extracellular region)|go:"GO:0005618"(cell wall)|go:"GO:0005886"(plasma membrane)|go:"GO:0044315"(protein secretion by the type VII secretion system)|refseq:NP_218131.1|refseq:WP_003419545.1	go:"GO:0003677"(DNA binding)|go:"GO:0005618"(cell wall)|go:"GO:0005886"(plasma membrane)|go:"GO:0052170"(suppression by symbiont of host innate immune response)|mint:P9WJB9|refseq:NP_218397.1|refseq:WP_003399988.1|interpro:IPR036894|interpro:IPR004401(Conserved hypothetical protein CHP00103)	-	-	-	figure legend:f8|comment:This interaction occurs also when espL is over-expressed with the HA tag at the C-terminus.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:83332(myctu)|taxid:83332("Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)")	-	2020/09/25	2020/09/25	rogid:vBZomfFzwpZES48O708xfl6PRYA83332	rogid:BspTx2RZuhJaQ319NBDIyOreqfE83332	rigid:ln2Toc/bRpyHJyyGL90Bgaw/KXQ	false	-	ha tag:n-n	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:P9WJD5	uniprotkb:P9WJB9	intact:EBI-26358082|uniprotkb:L0TEQ0|uniprotkb:O06269|uniprotkb:Q7D573	intact:EBI-25767670|uniprotkb:L0TE21|uniprotkb:O69744|uniprotkb:Q7D4P0	psi-mi:espd_myctu(display_long)|uniprotkb:espD(gene name)|psi-mi:espD(display_short)|uniprotkb:snm10(gene name synonym)|uniprotkb:Rv3614c(locus name)	psi-mi:espl_myctu(display_long)|uniprotkb:espL(gene name)|psi-mi:espL(display_short)|uniprotkb:Rv3880c(locus name)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Sala et al. (2018)	pubmed:30571761|imex:IM-28370	taxid:83332(myctu)|taxid:83332("Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)")	taxid:83332(myctu)|taxid:83332("Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)")	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26362494|imex:IM-28370-2	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	go:"GO:0005576"(extracellular region)|go:"GO:0005618"(cell wall)|go:"GO:0005886"(plasma membrane)|go:"GO:0044315"(protein secretion by the type VII secretion system)|refseq:NP_218131.1|refseq:WP_003419545.1	go:"GO:0003677"(DNA binding)|go:"GO:0005618"(cell wall)|go:"GO:0005886"(plasma membrane)|go:"GO:0052170"(suppression by symbiont of host innate immune response)|mint:P9WJB9|refseq:NP_218397.1|refseq:WP_003399988.1|interpro:IPR036894|interpro:IPR004401(Conserved hypothetical protein CHP00103)	-	-	-	figure legend:f8|comment:"Mass spectrometry analysis of the precipitated material demonstrated that EspD was significantly enriched in the pulled-down fractions of ΔespL/pGA-HA.espL and of ΔespL/pGA-espL.HA, together with HA.EspL and EspL.HA (S6 Table). Other proteins were detected but their abundance was not increased in the immunoprecipitated samples compared to the Input and to the untagged strains H37Rv and ΔespL"|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:83332(myctu)|taxid:83332("Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)")	-	2020/09/25	2020/09/30	rogid:vBZomfFzwpZES48O708xfl6PRYA83332	rogid:BspTx2RZuhJaQ319NBDIyOreqfE83332	rigid:ln2Toc/bRpyHJyyGL90Bgaw/KXQ	false	-	ha tag:n-n	-	-	psi-mi:"MI:0427"(Identification by mass spectrometry)	psi-mi:"MI:0427"(Identification by mass spectrometry)