#ID(s) interactor A ID(s) interactor B Alt. ID(s) interactor A Alt. ID(s) interactor B Alias(es) interactor A Alias(es) interactor B Interaction detection method(s) Publication 1st author(s) Publication Identifier(s) Taxid interactor A Taxid interactor B Interaction type(s) Source database(s) Interaction identifier(s) Confidence value(s) Expansion method(s) Biological role(s) interactor A Biological role(s) interactor B Experimental role(s) interactor A Experimental role(s) interactor B Type(s) interactor A Type(s) interactor B Xref(s) interactor A Xref(s) interactor B Interaction Xref(s) Annotation(s) interactor A Annotation(s) interactor B Interaction annotation(s) Host organism(s) Interaction parameter(s) Creation date Update date Checksum(s) interactor A Checksum(s) interactor B Interaction Checksum(s) Negative Feature(s) interactor A Feature(s) interactor B Stoichiometry(s) interactor A Stoichiometry(s) interactor B Identification method participant A Identification method participant B uniprotkb:Q8N5Y2-1 uniprotkb:Q9H7Z6 intact:EBI-15866726|ensembl:ENSP00000312244 intact:EBI-896414|uniprotkb:Q659G0|uniprotkb:Q7LC17|uniprotkb:Q8IY59|uniprotkb:Q8WYB4|uniprotkb:Q8WZ14|uniprotkb:Q9HAC5|uniprotkb:Q9NR35|uniprotkb:A8K4Z1|intact:EBI-2560822|uniprotkb:G5E9P2|ensembl:ENSP00000219797|ensembl:ENSP00000456933 psi-mi:q8n5y2-1(display_long)|uniprotkb:MSL3(gene name)|psi-mi:MSL3(display_short)|uniprotkb:MSL3L1(gene name synonym)|uniprotkb:Male-specific lethal-3 homolog 1(gene name synonym)|uniprotkb:Male-specific lethal-3 protein-like 1(gene name synonym) psi-mi:kat8_human(display_long)|uniprotkb:KAT8(gene name)|psi-mi:KAT8(display_short)|uniprotkb:MOF(gene name synonym)|uniprotkb:PP7073(orf name)|uniprotkb:MOZ, YBF2/SAS3, SAS2 and TIP60 protein 1(gene name synonym)|uniprotkb:MYST1(gene name synonym)|uniprotkb:Lysine acetyltransferase 8(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Basilicata et al. (2018) imex:IM-28463|pubmed:30224647 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-26435308|imex:IM-28463-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000005302(gene)|ensembl:ENST00000312196(transcript)|intact:EBI-2560796(isoform-parent) refseq:NP_115564.2|refseq:NP_892003.2|ensembl:ENSG00000103510(gene)|ensembl:ENST00000219797(transcript)|ensembl:ENST00000543774(transcript)|go:"GO:0000123"(histone acetyltransferase complex)|go:"GO:0000776"(kinetochore)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0004402"(histone acetyltransferase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0008134"(transcription factor binding)|go:"GO:0010506"(regulation of autophagy)|go:"GO:0016363"(nuclear matrix)|go:"GO:0016407"(acetyltransferase activity)|go:"GO:0016573"(histone acetylation)|go:"GO:0019899"(enzyme binding)|go:"GO:0030099"(myeloid cell differentiation)|go:"GO:0035064"(methylated histone binding)|go:"GO:0042393"(histone binding)|go:"GO:0043981"(histone H4-K5 acetylation)|go:"GO:0043982"(histone H4-K8 acetylation)|go:"GO:0043984"(histone H4-K16 acetylation)|go:"GO:0043995"("histone acetyltransferase activity (H4-K5 specific)")|go:"GO:0043996"("histone acetyltransferase activity (H4-K8 specific)")|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|go:"GO:0046972"("histone acetyltransferase activity (H4-K16 specific)")|go:"GO:0071339"(MLL1 complex)|go:"GO:0072487"(MSL complex)|interpro:IPR000953(Chromo domain)|interpro:IPR002717(MOZ/SAS-like protein)|interpro:IPR016181(Acyl-CoA N-acyltransferase)|interpro:IPR016197(Chromo domain-like)|interpro:IPR025995|interpro:IPR036388|interpro:IPR037906|interpro:IPR040706|mint:Q9H7Z6|rcsb pdb:2GIV|rcsb pdb:2PQ8|rcsb pdb:2Y0M|rcsb pdb:3QAH|rcsb pdb:3TOA|rcsb pdb:3TOB|rcsb pdb:4DNC|rcsb pdb:5H43|rcsb pdb:5J8C|rcsb pdb:5J8F|rcsb pdb:5WCI|rcsb pdb:6BA2|rcsb pdb:6BA4|rcsb pdb:6CT2|rcsb pdb:6OIN|rcsb pdb:6OIO|rcsb pdb:6OIP|rcsb pdb:6OIQ|rcsb pdb:6OIR|rcsb pdb:6OWH|rcsb pdb:6OWI|rcsb pdb:6PD8|rcsb pdb:6PD9|rcsb pdb:6PDA|rcsb pdb:6PDB|rcsb pdb:6PDC|rcsb pdb:6PDD|rcsb pdb:6PDE|rcsb pdb:6PDF|rcsb pdb:6PDG|rcsb pdb:7CMR|reactome:R-HSA-3214847 - - - figure legend:Fig.1H|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293 flp-in)|taxid:9606(Homo sapiens) - 2020/10/29 2020/10/29 rogid:uZsUcEHPwWI+o+d7aGwhfnxVltA9606 rogid:CIkEOWd9OuFyigFJ02ORCqVbXHE9606 rigid:29FvP1QAdw2p63OCPATwPsNv3co false flag tag:c-c|his tag:c-c|biotin tag:c-c|necessary binding region:460-521 - - - psi-mi:"MI:0705"(anti tag western blot) psi-mi:"MI:0705"(anti tag western blot) uniprotkb:Q8N5Y2-1 uniprotkb:Q68DK7 intact:EBI-15866726|ensembl:ENSP00000312244 intact:EBI-2560816|ensembl:ENSP00000381543|uniprotkb:Q69Z03|uniprotkb:Q0VF46|intact:EBI-2654071 psi-mi:q8n5y2-1(display_long)|uniprotkb:MSL3(gene name)|psi-mi:MSL3(display_short)|uniprotkb:MSL3L1(gene name synonym)|uniprotkb:Male-specific lethal-3 homolog 1(gene name synonym)|uniprotkb:Male-specific lethal-3 protein-like 1(gene name synonym) psi-mi:msl1_human(display_long)|uniprotkb:MSL1(gene name)|psi-mi:MSL1(display_short)|uniprotkb:MSL1L1(gene name synonym)|uniprotkb:Male-specific lethal 1-like 1(gene name synonym)|uniprotkb:Male-specific lethal-1 homolog 1(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Basilicata et al. (2018) imex:IM-28463|pubmed:30224647 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-26435308|imex:IM-28463-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000005302(gene)|ensembl:ENST00000312196(transcript)|intact:EBI-2560796(isoform-parent) ensembl:ENSG00000188895(gene)|ensembl:ENST00000398532(transcript)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0016607"(nuclear speck)|go:"GO:0043984"(histone H4-K16 acetylation)|go:"GO:0072487"(MSL complex)|interpro:IPR026711|interpro:IPR029332|interpro:IPR031840|mint:Q68DK7|rcsb pdb:4B7Y|rcsb pdb:4B86|rcsb pdb:4DNC|reactome:R-HSA-3214847|refseq:NP_001012241.1|refseq:XP_005257355.1|dip:DIP-56862N - - - figure legend:Fig.1H|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293 flp-in)|taxid:9606(Homo sapiens) - 2020/10/29 2020/10/29 rogid:uZsUcEHPwWI+o+d7aGwhfnxVltA9606 rogid:sFenPEZNoGtpn1bDFoUzSJBPUBY9606 rigid:29FvP1QAdw2p63OCPATwPsNv3co false flag tag:c-c|his tag:c-c|biotin tag:c-c|necessary binding region:460-521 ha tag:c-c - - psi-mi:"MI:0705"(anti tag western blot) psi-mi:"MI:0705"(anti tag western blot) uniprotkb:Q9H7Z6-1 uniprotkb:Q8N5Y2-1 intact:EBI-26435386|ensembl:ENSP00000219797|ensembl:ENSP00000456933 intact:EBI-15866726|ensembl:ENSP00000312244 psi-mi:q9h7z6-1(display_long)|uniprotkb:Lysine acetyltransferase 8(gene name synonym)|uniprotkb:MOZ, YBF2/SAS3, SAS2 and TIP60 protein 1(gene name synonym)|uniprotkb:KAT8(gene name)|psi-mi:KAT8(display_short)|uniprotkb:MOF(gene name synonym)|uniprotkb:MYST1(gene name synonym)|uniprotkb:PP7073(orf name) psi-mi:q8n5y2-1(display_long)|uniprotkb:MSL3(gene name)|psi-mi:MSL3(display_short)|uniprotkb:MSL3L1(gene name synonym)|uniprotkb:Male-specific lethal-3 homolog 1(gene name synonym)|uniprotkb:Male-specific lethal-3 protein-like 1(gene name synonym) psi-mi:"MI:0096"(pull down) Basilicata et al. (2018) imex:IM-28463|pubmed:30224647 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-26435370|imex:IM-28463-2 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-896414(isoform-parent)|ensembl:ENSG00000103510(gene)|ensembl:ENST00000219797(transcript)|ensembl:ENST00000543774(transcript) ensembl:ENSG00000005302(gene)|ensembl:ENST00000312196(transcript)|intact:EBI-2560796(isoform-parent) - - - figure legend:Fig.1E|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:83333(ecoli)|taxid:83333("Escherichia coli (strain K12)") - 2020/10/29 2020/10/29 rogid:CIkEOWd9OuFyigFJ02ORCqVbXHE9606 rogid:uZsUcEHPwWI+o+d7aGwhfnxVltA9606 rigid:29FvP1QAdw2p63OCPATwPsNv3co false sufficient binding region:174-458|his tag:n-n sufficient binding region:167-517 - - psi-mi:"MI:0818"(molecular weight estimation by coomasie staining) psi-mi:"MI:0818"(molecular weight estimation by coomasie staining) uniprotkb:Q9H7Z6-1 uniprotkb:Q68DK7-1 intact:EBI-26435386|ensembl:ENSP00000219797|ensembl:ENSP00000456933 intact:EBI-26435399|ensembl:ENSP00000381543 psi-mi:q9h7z6-1(display_long)|uniprotkb:Lysine acetyltransferase 8(gene name synonym)|uniprotkb:MOZ, YBF2/SAS3, SAS2 and TIP60 protein 1(gene name synonym)|uniprotkb:KAT8(gene name)|psi-mi:KAT8(display_short)|uniprotkb:MOF(gene name synonym)|uniprotkb:MYST1(gene name synonym)|uniprotkb:PP7073(orf name) psi-mi:q68dk7-1(display_long)|uniprotkb:MSL1(gene name)|psi-mi:MSL1(display_short)|uniprotkb:MSL1L1(gene name synonym)|uniprotkb:Male-specific lethal 1-like 1(gene name synonym)|uniprotkb:Male-specific lethal-1 homolog 1(gene name synonym) psi-mi:"MI:0096"(pull down) Basilicata et al. (2018) imex:IM-28463|pubmed:30224647 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-26435370|imex:IM-28463-2 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-896414(isoform-parent)|ensembl:ENSG00000103510(gene)|ensembl:ENST00000219797(transcript)|ensembl:ENST00000543774(transcript) ensembl:ENSG00000188895(gene)|ensembl:ENST00000398532(transcript)|intact:EBI-2560816(isoform-parent) - - - figure legend:Fig.1E|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:83333(ecoli)|taxid:83333("Escherichia coli (strain K12)") - 2020/10/29 2020/10/29 rogid:CIkEOWd9OuFyigFJ02ORCqVbXHE9606 rogid:sFenPEZNoGtpn1bDFoUzSJBPUBY9606 rigid:29FvP1QAdw2p63OCPATwPsNv3co false sufficient binding region:174-458|his tag:n-n sufficient binding region:471-614 - - psi-mi:"MI:0818"(molecular weight estimation by coomasie staining) psi-mi:"MI:0818"(molecular weight estimation by coomasie staining) uniprotkb:Q9H7Z6-1 uniprotkb:Q68DK7-1 intact:EBI-26435386|ensembl:ENSP00000219797|ensembl:ENSP00000456933 intact:EBI-26435399|ensembl:ENSP00000381543 psi-mi:q9h7z6-1(display_long)|uniprotkb:Lysine acetyltransferase 8(gene name synonym)|uniprotkb:MOZ, YBF2/SAS3, SAS2 and TIP60 protein 1(gene name synonym)|uniprotkb:KAT8(gene name)|psi-mi:KAT8(display_short)|uniprotkb:MOF(gene name synonym)|uniprotkb:MYST1(gene name synonym)|uniprotkb:PP7073(orf name) psi-mi:q68dk7-1(display_long)|uniprotkb:MSL1(gene name)|psi-mi:MSL1(display_short)|uniprotkb:MSL1L1(gene name synonym)|uniprotkb:Male-specific lethal 1-like 1(gene name synonym)|uniprotkb:Male-specific lethal-1 homolog 1(gene name synonym) psi-mi:"MI:0096"(pull down) Basilicata et al. (2018) imex:IM-28463|pubmed:30224647 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0486"(UniProt) intact:EBI-26435414|imex:IM-28463-4 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-896414(isoform-parent)|ensembl:ENSG00000103510(gene)|ensembl:ENST00000219797(transcript)|ensembl:ENST00000543774(transcript) ensembl:ENSG00000188895(gene)|ensembl:ENST00000398532(transcript)|intact:EBI-2560816(isoform-parent) - - - figure legend:Fig.1E|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:83333(ecoli)|taxid:83333("Escherichia coli (strain K12)") - 2020/10/29 2020/10/29 rogid:CIkEOWd9OuFyigFJ02ORCqVbXHE9606 rogid:sFenPEZNoGtpn1bDFoUzSJBPUBY9606 rigid:kiwPSz9yDf8jWtfwjySovSatQ64 false sufficient binding region:174-458|his tag:n-n sufficient binding region:471-614 - - psi-mi:"MI:0818"(molecular weight estimation by coomasie staining) psi-mi:"MI:0818"(molecular weight estimation by coomasie staining)