#ID(s) interactor A ID(s) interactor B Alt. ID(s) interactor A Alt. ID(s) interactor B Alias(es) interactor A Alias(es) interactor B Interaction detection method(s) Publication 1st author(s) Publication Identifier(s) Taxid interactor A Taxid interactor B Interaction type(s) Source database(s) Interaction identifier(s) Confidence value(s) Expansion method(s) Biological role(s) interactor A Biological role(s) interactor B Experimental role(s) interactor A Experimental role(s) interactor B Type(s) interactor A Type(s) interactor B Xref(s) interactor A Xref(s) interactor B Interaction Xref(s) Annotation(s) interactor A Annotation(s) interactor B Interaction annotation(s) Host organism(s) Interaction parameter(s) Creation date Update date Checksum(s) interactor A Checksum(s) interactor B Interaction Checksum(s) Negative Feature(s) interactor A Feature(s) interactor B Stoichiometry(s) interactor A Stoichiometry(s) interactor B Identification method participant A Identification method participant B uniprotkb:Q9BY14 uniprotkb:Q9BYF1 intact:EBI-12549378|ensembl:ENSP00000472769|uniprotkb:Q7L5R2|uniprotkb:Q9BPY7 intact:EBI-7730807|ensembl:ENSP00000252519|ensembl:ENSP00000389326|ensembl:ENSP00000504103|ensembl:ENSP00000505992|intact:EBI-25767352|uniprotkb:Q9UFZ6|uniprotkb:Q9NRA7|intact:MINT-4538816|uniprotkb:C7ECU1|uniprotkb:Q6UWP0|uniprotkb:Q86WT0|uniprotkb:A0A7D6JAD5|intact:EBI-15814450 psi-mi:tx101_human(display_long)|uniprotkb:TEX101(gene name)|psi-mi:TEX101(display_short)|uniprotkb:Cell surface receptor NYD-SP8(gene name synonym)|uniprotkb:SGRG(gene name synonym)|uniprotkb:Scleroderma-associated autoantigen(gene name synonym)|uniprotkb:Spermatogenesis-related gene protein(gene name synonym)|uniprotkb:UNQ867/PRO1884(orf name) psi-mi:ace2_human(display_long)|uniprotkb:ACE2(gene name)|psi-mi:ACE2(display_short)|uniprotkb:UNQ868/PRO1885(orf name)|uniprotkb:Angiotensin-converting enzyme homolog(gene name synonym)|uniprotkb:Metalloprotease MPROT15(gene name synonym)|uniprotkb:Angiotensin-converting enzyme-related carboxypeptidase(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Schiza et al. (2018) imex:IM-28077|pubmed:30097533 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-25504841|imex:IM-28077-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000131126(gene)|ensembl:ENST00000598265(transcript)|go:"GO:0001669"(acrosomal vesicle)|go:"GO:0002080"(acrosomal membrane)|go:"GO:0005576"(extracellular region)|go:"GO:0005886"(plasma membrane)|go:"GO:0007339"(binding of sperm to zona pellucida)|go:"GO:0009566"(fertilization)|go:"GO:0030317"(flagellated sperm motility)|go:"GO:0044853"(plasma membrane raft)|go:"GO:0046658"(anchored component of plasma membrane)|go:"GO:1901317"(regulation of flagellated sperm motility)|interpro:IPR016054(Ly-6 antigen / uPA receptor -like)|rcsb pdb:7BPR|reactome:R-HSA-163125|refseq:NP_001123483.1|refseq:NP_113639.4 ensembl:ENST00000252519(transcript)|ensembl:ENST00000427411(transcript)|ensembl:ENST00000678073(transcript)|ensembl:ENST00000680121(transcript)|go:"GO:0001618"(virus receptor activity)|go:"GO:0001817"(regulation of cytokine production)|go:"GO:0002003"(angiotensin maturation)|go:"GO:0003051"(angiotensin-mediated drinking behavior)|go:"GO:0003081"(regulation of systemic arterial blood pressure by renin-angiotensin)|go:"GO:0004175"(endopeptidase activity)|go:"GO:0004180"(carboxypeptidase activity)|go:"GO:0004181"(metallocarboxypeptidase activity)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0005788"(endoplasmic reticulum lumen)|go:"GO:0005886"(plasma membrane)|go:"GO:0005929"(cilium)|go:"GO:0006508"(proteolysis)|go:"GO:0008237"(metallopeptidase activity)|go:"GO:0008241"(peptidyl-dipeptidase activity)|go:"GO:0008270"(zinc ion binding)|go:"GO:0009986"(cell surface)|go:"GO:0015827"(tryptophan transport)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0019229"(regulation of vasoconstriction)|go:"GO:0022898"(regulation of transmembrane transporter activity)|go:"GO:0030666"(endocytic vesicle membrane)|go:"GO:0031526"(brush border membrane)|go:"GO:0042127"(regulation of cell population proliferation)|go:"GO:0042802"(identical protein binding)|go:"GO:0045121"(membrane raft)|go:"GO:0046718"(viral entry into host cell)|go:"GO:0046813"(receptor-mediated virion attachment to host cell)|ensembl:ENSG00000130234(gene)|go:"GO:0051957"(positive regulation of amino acid transport)|go:"GO:0060452"(positive regulation of cardiac muscle contraction)|go:"GO:0070062"(extracellular exosome)|go:"GO:0097746"(blood vessel diameter maintenance)|go:"GO:1903598"(positive regulation of gap junction assembly)|go:"GO:1903779"(regulation of cardiac conduction)|go:"GO:1905737"(positive regulation of L-proline import across plasma membrane)|go:"GO:2000272"(negative regulation of signaling receptor activity)|go:"GO:2000379"(positive regulation of reactive oxygen species metabolic process)|interpro:IPR001548(Peptidase M2, peptidyl-dipeptidase A)|interpro:IPR031588|mint:Q9BYF1|rcsb pdb:1R42|rcsb pdb:1R4L|rcsb pdb:1XJP|rcsb pdb:2AJF|rcsb pdb:3D0G|rcsb pdb:3D0H|rcsb pdb:3D0I|rcsb pdb:3KBH|rcsb pdb:3SCI|rcsb pdb:3SCJ|rcsb pdb:3SCK|rcsb pdb:3SCL|rcsb pdb:6ACG|rcsb pdb:6ACJ|rcsb pdb:6ACK|rcsb pdb:6CS2|rcsb pdb:6LZG|rcsb pdb:6M0J|rcsb pdb:6M17|rcsb pdb:6M18|go:"GO:0050727"(regulation of inflammatory response)|rcsb pdb:6M1D|rcsb pdb:6VW1|rcsb pdb:7A91|rcsb pdb:7A92|rcsb pdb:7A94|rcsb pdb:7A95|rcsb pdb:7A96|rcsb pdb:7A97|rcsb pdb:7A98|rcsb pdb:7BH9|rcsb pdb:7CT5|rcsb pdb:7DDO|rcsb pdb:7DDP|rcsb pdb:7DF4|rcsb pdb:7DMU|rcsb pdb:7DWX|rcsb pdb:7DX4|rcsb pdb:7DX5|rcsb pdb:7DX6|rcsb pdb:7DX7|rcsb pdb:7DX8|rcsb pdb:7DX9|rcsb pdb:7JVO|rcsb pdb:7KJ2|rcsb pdb:7KJ3|rcsb pdb:7KJ4|rcsb pdb:7KMB|rcsb pdb:7KMS|rcsb pdb:7KMZ|rcsb pdb:7KNB|rcsb pdb:7KNE|rcsb pdb:7KNH|rcsb pdb:7L0N|rcsb pdb:7L7F|rcsb pdb:7LO4|rcsb pdb:7MJM|rcsb pdb:7MJN|rcsb pdb:7NXC|reactome:R-HSA-2022377|reactome:R-HSA-9678110|reactome:R-HSA-9679191|reactome:R-HSA-9694614|rcsb pdb:7KNI|dip:DIP-44689N|refseq:NP_068576.1 - - comment:mint|function:Carboxypeptidase which converts angiotensin I to angiotensin 1-9, a peptide of unknown function, and angiotensin II to angiotensin 1-7, a vasodilator. Also able to hydrolyze apelin-13 and dynorphin-13 with high efficiency. May be an important regulator of heart function. In case of human coronaviruses SARS and HCoV-NL63 infections, serve as functional receptor for the spike glycoprotein of both coronaviruses figure legend:Supp Table S4 and Supp Fig. S3|comment:"Coimmunoprecipitation with 34ED229 (T2) anti-TEX101 antibody"|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-testis)|taxid:9606(Homo sapiens) - 2020/03/24 2020/06/18 rogid:ZE4tXTFi7lUCcIbCL4KHzY3a6xM9606 rogid:ZxuR6gzxz4Ns+hYH5uksGdn8S7o9606 rigid:2wTqH12DHkSLcixvnxiJPZhqAc0 false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9BY14 uniprotkb:P11216 intact:EBI-12549378|ensembl:ENSP00000472769|uniprotkb:Q7L5R2|uniprotkb:Q9BPY7 intact:EBI-1047231|uniprotkb:Q96AK1|uniprotkb:Q9NPX8|ensembl:ENSP00000216962 psi-mi:tx101_human(display_long)|uniprotkb:TEX101(gene name)|psi-mi:TEX101(display_short)|uniprotkb:Cell surface receptor NYD-SP8(gene name synonym)|uniprotkb:SGRG(gene name synonym)|uniprotkb:Scleroderma-associated autoantigen(gene name synonym)|uniprotkb:Spermatogenesis-related gene protein(gene name synonym)|uniprotkb:UNQ867/PRO1884(orf name) psi-mi:pygb_human(display_long)|uniprotkb:PYGB(gene name)|psi-mi:PYGB(display_short) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Schiza et al. (2018) imex:IM-28077|pubmed:30097533 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-25504841|imex:IM-28077-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000131126(gene)|ensembl:ENST00000598265(transcript)|go:"GO:0001669"(acrosomal vesicle)|go:"GO:0002080"(acrosomal membrane)|go:"GO:0005576"(extracellular region)|go:"GO:0005886"(plasma membrane)|go:"GO:0007339"(binding of sperm to zona pellucida)|go:"GO:0009566"(fertilization)|go:"GO:0030317"(flagellated sperm motility)|go:"GO:0044853"(plasma membrane raft)|go:"GO:0046658"(anchored component of plasma membrane)|go:"GO:1901317"(regulation of flagellated sperm motility)|interpro:IPR016054(Ly-6 antigen / uPA receptor -like)|rcsb pdb:7BPR|reactome:R-HSA-163125|refseq:NP_001123483.1|refseq:NP_113639.4 ensembl:ENSG00000100994(gene)|ensembl:ENST00000216962(transcript)|go:"GO:0005576"(extracellular region)|go:"GO:0005737"(cytoplasm)|go:"GO:0005980"(glycogen catabolic process)|go:"GO:0008184"(glycogen phosphorylase activity)|go:"GO:0016020"(membrane)|go:"GO:0030170"(pyridoxal phosphate binding)|go:"GO:0035578"(azurophil granule lumen)|go:"GO:0070062"(extracellular exosome)|go:"GO:0102250"(linear malto-oligosaccharide phosphorylase activity)|go:"GO:0102499"(SHG alpha-glucan phosphorylase activity)|interpro:IPR000811(Glycosyl transferase, family 35)|interpro:IPR011833(Glycogen/starch/alpha-glucan phosphorylase)|interpro:IPR035090|mint:P11216|rcsb pdb:5IKO|rcsb pdb:5IKP|reactome:R-HSA-6798695|reactome:R-HSA-70221|refseq:NP_002853.2 - - - figure legend:Supp Table S4 and Supp Fig. S3|comment:"Coimmunoprecipitation with 34ED229 (T2) anti-TEX101 antibody"|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-testis)|taxid:9606(Homo sapiens) - 2020/03/24 2020/06/18 rogid:ZE4tXTFi7lUCcIbCL4KHzY3a6xM9606 rogid:nJiqOiqRr155pMoMKe4PuD1DpLc9606 rigid:2wTqH12DHkSLcixvnxiJPZhqAc0 false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9BY14 uniprotkb:P21964 intact:EBI-12549378|ensembl:ENSP00000472769|uniprotkb:Q7L5R2|uniprotkb:Q9BPY7 intact:EBI-372265|uniprotkb:Q6IB07|uniprotkb:Q6ICE6|uniprotkb:A8MPV9|intact:EBI-743305|uniprotkb:Q9BWC7|intact:EBI-11576026|ensembl:ENSP00000354511|ensembl:ENSP00000384654|ensembl:ENSP00000385150|ensembl:ENSP00000385917|ensembl:ENSP00000503583|ensembl:ENSP00000503719|ensembl:ENSP00000504402 psi-mi:tx101_human(display_long)|uniprotkb:TEX101(gene name)|psi-mi:TEX101(display_short)|uniprotkb:Cell surface receptor NYD-SP8(gene name synonym)|uniprotkb:SGRG(gene name synonym)|uniprotkb:Scleroderma-associated autoantigen(gene name synonym)|uniprotkb:Spermatogenesis-related gene protein(gene name synonym)|uniprotkb:UNQ867/PRO1884(orf name) psi-mi:comt_human(display_long)|uniprotkb:COMT(gene name)|psi-mi:COMT(display_short) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Schiza et al. (2018) imex:IM-28077|pubmed:30097533 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-25504841|imex:IM-28077-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000131126(gene)|ensembl:ENST00000598265(transcript)|go:"GO:0001669"(acrosomal vesicle)|go:"GO:0002080"(acrosomal membrane)|go:"GO:0005576"(extracellular region)|go:"GO:0005886"(plasma membrane)|go:"GO:0007339"(binding of sperm to zona pellucida)|go:"GO:0009566"(fertilization)|go:"GO:0030317"(flagellated sperm motility)|go:"GO:0044853"(plasma membrane raft)|go:"GO:0046658"(anchored component of plasma membrane)|go:"GO:1901317"(regulation of flagellated sperm motility)|interpro:IPR016054(Ly-6 antigen / uPA receptor -like)|rcsb pdb:7BPR|reactome:R-HSA-163125|refseq:NP_001123483.1|refseq:NP_113639.4 refseq:NP_000745.1|refseq:NP_001128633.1|refseq:NP_001128634.1|refseq:NP_009294.1|refseq:XP_016884083.1|refseq:XP_016884084.1|ensembl:ENSG00000093010(gene)|ensembl:ENST00000361682(transcript)|ensembl:ENST00000403710(transcript)|ensembl:ENST00000406520(transcript)|ensembl:ENST00000407537(transcript)|ensembl:ENST00000676678(transcript)|ensembl:ENST00000678255(transcript)|ensembl:ENST00000678868(transcript)|go:"GO:0000287"(magnesium ion binding)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0007565"(female pregnancy)|go:"GO:0007612"(learning)|go:"GO:0007614"(short-term memory)|go:"GO:0008168"(methyltransferase activity)|go:"GO:0008171"(O-methyltransferase activity)|go:"GO:0008210"(estrogen metabolic process)|go:"GO:0014070"(response to organic cyclic compound)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016036"(cellular response to phosphate starvation)|go:"GO:0016206"(catechol O-methyltransferase activity)|go:"GO:0030424"(axon)|go:"GO:0030425"(dendrite)|go:"GO:0032259"(methylation)|go:"GO:0032496"(response to lipopolysaccharide)|go:"GO:0032502"(developmental process)|go:"GO:0035814"(negative regulation of renal sodium excretion)|go:"GO:0042135"(neurotransmitter catabolic process)|go:"GO:0042417"(dopamine metabolic process)|go:"GO:0042420"(dopamine catabolic process)|go:"GO:0042424"(catecholamine catabolic process)|go:"GO:0042493"|go:"GO:0043197"(dendritic spine)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0043627"(response to estrogen)|go:"GO:0044297"(cell body)|go:"GO:0045211"(postsynaptic membrane)|go:"GO:0045963"(negative regulation of dopamine metabolic process)|go:"GO:0048265"(response to pain)|go:"GO:0048609"(multicellular organismal reproductive process)|go:"GO:0048662"(negative regulation of smooth muscle cell proliferation)|go:"GO:0050668"(positive regulation of homocysteine metabolic process)|go:"GO:0051930"(regulation of sensory perception of pain)|go:"GO:0070062"(extracellular exosome)|go:"GO:0102084"(L-dopa O-methyltransferase activity)|go:"GO:0102938"(orcinol O-methyltransferase activity)|interpro:IPR002935(O-methyltransferase, family 3)|interpro:IPR017128(Catechol O-methyltransferase, eukaryotic)|interpro:IPR029063|mint:P21964|rcsb pdb:3A7E|rcsb pdb:3BWM|rcsb pdb:3BWY|rcsb pdb:4PYI|rcsb pdb:4PYJ|rcsb pdb:4PYK|rcsb pdb:4XUD|rcsb pdb:4XUE|rcsb pdb:5LSA|rcsb pdb:6I3C|rcsb pdb:6I3D|reactome:R-HSA-156581|reactome:R-HSA-379397|reactome:R-HSA-379398|reactome:R-HSA-9679191|rcsb pdb:4XUC - - - figure legend:Supp Table S4 and Supp Fig. S3|comment:"Coimmunoprecipitation with 34ED229 (T2) anti-TEX101 antibody"|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-testis)|taxid:9606(Homo sapiens) - 2020/03/24 2020/06/18 rogid:ZE4tXTFi7lUCcIbCL4KHzY3a6xM9606 rogid:3Fnq8iVqPpOWNX6QQuiNRSsTFN09606 rigid:2wTqH12DHkSLcixvnxiJPZhqAc0 false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9BY14 uniprotkb:P07437 intact:EBI-12549378|ensembl:ENSP00000472769|uniprotkb:Q7L5R2|uniprotkb:Q9BPY7 intact:EBI-350864|uniprotkb:P05218|uniprotkb:Q8WUC1|uniprotkb:Q9CY33|ensembl:ENSP00000339001|ensembl:ENSP00000373058|ensembl:ENSP00000399155|ensembl:ENSP00000400663|ensembl:ENSP00000401317|ensembl:ENSP00000406811|ensembl:ENSP00000410071|ensembl:ENSP00000410829 psi-mi:tx101_human(display_long)|uniprotkb:TEX101(gene name)|psi-mi:TEX101(display_short)|uniprotkb:Cell surface receptor NYD-SP8(gene name synonym)|uniprotkb:SGRG(gene name synonym)|uniprotkb:Scleroderma-associated autoantigen(gene name synonym)|uniprotkb:Spermatogenesis-related gene protein(gene name synonym)|uniprotkb:UNQ867/PRO1884(orf name) psi-mi:tbb5_human(display_long)|uniprotkb:TUBB(gene name)|psi-mi:TUBB(display_short)|uniprotkb:Tubulin beta-5 chain(gene name synonym)|uniprotkb:TUBB5(gene name synonym)|uniprotkb:OK/SW-cl.56(orf name) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Schiza et al. (2018) imex:IM-28077|pubmed:30097533 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-25504841|imex:IM-28077-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000131126(gene)|ensembl:ENST00000598265(transcript)|go:"GO:0001669"(acrosomal vesicle)|go:"GO:0002080"(acrosomal membrane)|go:"GO:0005576"(extracellular region)|go:"GO:0005886"(plasma membrane)|go:"GO:0007339"(binding of sperm to zona pellucida)|go:"GO:0009566"(fertilization)|go:"GO:0030317"(flagellated sperm motility)|go:"GO:0044853"(plasma membrane raft)|go:"GO:0046658"(anchored component of plasma membrane)|go:"GO:1901317"(regulation of flagellated sperm motility)|interpro:IPR016054(Ly-6 antigen / uPA receptor -like)|rcsb pdb:7BPR|reactome:R-HSA-163125|refseq:NP_001123483.1|refseq:NP_113639.4 refseq:NP_821133.1|refseq:NP_001280141.1|refseq:NP_001280142.1|refseq:NP_001280143.1|refseq:NP_001280144.1|refseq:NP_001280145.1|ensembl:ENSG00000183311(gene)|ensembl:ENSG00000196230(gene)|ensembl:ENSG00000224156(gene)|ensembl:ENSG00000227739(gene)|ensembl:ENSG00000229684(gene)|ensembl:ENSG00000232421(gene)|ensembl:ENSG00000232575(gene)|ensembl:ENSG00000235067(gene)|ensembl:ENST00000327892(transcript)|ensembl:ENST00000383564(transcript)|ensembl:ENST00000419792(transcript)|ensembl:ENST00000421473(transcript)|ensembl:ENST00000422650(transcript)|ensembl:ENST00000422674(transcript)|ensembl:ENST00000432462(transcript)|ensembl:ENST00000436628(transcript)|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005200"(structural constituent of cytoskeleton)|go:"GO:0005525"(GTP binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005634"(nucleus)|go:"GO:0005641"(nuclear envelope lumen)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005874"(microtubule)|go:"GO:0007017"(microtubule-based process)|go:"GO:0009987"(cellular process)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030705"(cytoskeleton-dependent intracellular transport)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032794"(GTPase activating protein binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035578"(azurophil granule lumen)|go:"GO:0036464"(cytoplasmic ribonucleoprotein granule)|go:"GO:0042267"(natural killer cell mediated cytotoxicity)|go:"GO:0042288"(MHC class I protein binding)|go:"GO:0044297"(cell body)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045121"(membrane raft)|go:"GO:0051225"(spindle assembly)|go:"GO:0051301"(cell division)|go:"GO:0070062"(extracellular exosome)|interpro:IPR000217(Tubulin)|interpro:IPR002453(Beta tubulin)|interpro:IPR003008(Tubulin/FtsZ, GTPase)|interpro:IPR008280(Tubulin/FtsZ, C-terminal)|interpro:IPR013838(Beta tubulin, autoregulation binding site)|interpro:IPR017975|interpro:IPR018316|interpro:IPR023123|interpro:IPR036525|interpro:IPR037103|mint:P07437|rcsb pdb:3QNZ|rcsb pdb:3QO0|rcsb pdb:5N5N|rcsb pdb:6I2I|rcsb pdb:6QUS|rcsb pdb:6QUY|rcsb pdb:6QVE|rcsb pdb:6QVJ|reactome:R-HSA-2565942|go:"GO:0050807"(regulation of synapse organization)|reactome:R-HSA-380259|reactome:R-HSA-380270|reactome:R-HSA-380284|reactome:R-HSA-5620912|reactome:R-HSA-6798695|reactome:R-HSA-8854518|reactome:R-HSA-9679191|reactome:R-HSA-380320|dip:DIP-32772N - - - figure legend:Supp Table S4 and Supp Fig. S3|comment:"Coimmunoprecipitation with 34ED229 (T2) anti-TEX101 antibody"|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-testis)|taxid:9606(Homo sapiens) - 2020/03/24 2020/06/18 rogid:ZE4tXTFi7lUCcIbCL4KHzY3a6xM9606 rogid:B6pmb1dvCroZXGd/1Zazi+s72GA9606 rigid:2wTqH12DHkSLcixvnxiJPZhqAc0 false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9BY14 uniprotkb:P61163 intact:EBI-12549378|ensembl:ENSP00000472769|uniprotkb:Q7L5R2|uniprotkb:Q9BPY7 intact:EBI-774234|uniprotkb:P42024|uniprotkb:B2R6B0|ensembl:ENSP00000358921 psi-mi:tx101_human(display_long)|uniprotkb:TEX101(gene name)|psi-mi:TEX101(display_short)|uniprotkb:Cell surface receptor NYD-SP8(gene name synonym)|uniprotkb:SGRG(gene name synonym)|uniprotkb:Scleroderma-associated autoantigen(gene name synonym)|uniprotkb:Spermatogenesis-related gene protein(gene name synonym)|uniprotkb:UNQ867/PRO1884(orf name) psi-mi:actz_human(display_long)|uniprotkb:Centrosome-associated actin homolog(gene name synonym)|uniprotkb:Actin-RPV(gene name synonym)|uniprotkb:ARP1(gene name synonym)|uniprotkb:ACTR1A(gene name)|psi-mi:ACTR1A(display_short)|uniprotkb:CTRN1(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Schiza et al. (2018) imex:IM-28077|pubmed:30097533 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-25504841|imex:IM-28077-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000131126(gene)|ensembl:ENST00000598265(transcript)|go:"GO:0001669"(acrosomal vesicle)|go:"GO:0002080"(acrosomal membrane)|go:"GO:0005576"(extracellular region)|go:"GO:0005886"(plasma membrane)|go:"GO:0007339"(binding of sperm to zona pellucida)|go:"GO:0009566"(fertilization)|go:"GO:0030317"(flagellated sperm motility)|go:"GO:0044853"(plasma membrane raft)|go:"GO:0046658"(anchored component of plasma membrane)|go:"GO:1901317"(regulation of flagellated sperm motility)|interpro:IPR016054(Ly-6 antigen / uPA receptor -like)|rcsb pdb:7BPR|reactome:R-HSA-163125|refseq:NP_001123483.1|refseq:NP_113639.4 refseq:NP_005727.1|ensembl:ENSG00000138107(gene)|ensembl:ENST00000369905(transcript)|go:"GO:0002177"(manchette)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005814"(centriole)|go:"GO:0005829"(cytosol)|go:"GO:0005869"(dynactin complex)|go:"GO:0005875"(microtubule associated complex)|go:"GO:0007283"(spermatogenesis)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0016192"(vesicle-mediated transport)|go:"GO:0030137"(COPI-coated vesicle)|go:"GO:0070062"(extracellular exosome)|go:"GO:0099738"(cell cortex region)|interpro:IPR004000(Actin/actin-like)|interpro:IPR004001(Actin, conserved site)|interpro:IPR020902|interpro:IPR043129|mint:P61163|reactome:R-HSA-2132295|reactome:R-HSA-2565942|reactome:R-HSA-3371497|reactome:R-HSA-380259|reactome:R-HSA-380270|reactome:R-HSA-380284|reactome:R-HSA-380320|reactome:R-HSA-5620912|reactome:R-HSA-6807878|reactome:R-HSA-6811436|reactome:R-HSA-8854518 - - - figure legend:Supp Table S4 and Supp Fig. S3|comment:"Coimmunoprecipitation with 34ED229 (T2) anti-TEX101 antibody"|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-testis)|taxid:9606(Homo sapiens) - 2020/03/24 2020/06/18 rogid:ZE4tXTFi7lUCcIbCL4KHzY3a6xM9606 rogid:aJHKOSj1qmZ7Pk8aZAyWWd8DEdw9606 rigid:2wTqH12DHkSLcixvnxiJPZhqAc0 false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9BY14 uniprotkb:Q06210 intact:EBI-12549378|ensembl:ENSP00000472769|uniprotkb:Q7L5R2|uniprotkb:Q9BPY7 intact:EBI-1055540|uniprotkb:Q9BXF8|uniprotkb:Q53QE6|ensembl:ENSP00000349860 psi-mi:tx101_human(display_long)|uniprotkb:TEX101(gene name)|psi-mi:TEX101(display_short)|uniprotkb:Cell surface receptor NYD-SP8(gene name synonym)|uniprotkb:SGRG(gene name synonym)|uniprotkb:Scleroderma-associated autoantigen(gene name synonym)|uniprotkb:Spermatogenesis-related gene protein(gene name synonym)|uniprotkb:UNQ867/PRO1884(orf name) psi-mi:gfpt1_human(display_long)|uniprotkb:D-fructose-6-phosphate amidotransferase 1(gene name synonym)|uniprotkb:Hexosephosphate aminotransferase 1(gene name synonym)|uniprotkb:GFPT1(gene name)|psi-mi:GFPT1(display_short)|uniprotkb:GFAT(gene name synonym)|uniprotkb:GFPT(gene name synonym)|uniprotkb:"Glutamine:fructose-6-phosphate amidotransferase 1"(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Schiza et al. (2018) imex:IM-28077|pubmed:30097533 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-25504841|imex:IM-28077-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000131126(gene)|ensembl:ENST00000598265(transcript)|go:"GO:0001669"(acrosomal vesicle)|go:"GO:0002080"(acrosomal membrane)|go:"GO:0005576"(extracellular region)|go:"GO:0005886"(plasma membrane)|go:"GO:0007339"(binding of sperm to zona pellucida)|go:"GO:0009566"(fertilization)|go:"GO:0030317"(flagellated sperm motility)|go:"GO:0044853"(plasma membrane raft)|go:"GO:0046658"(anchored component of plasma membrane)|go:"GO:1901317"(regulation of flagellated sperm motility)|interpro:IPR016054(Ly-6 antigen / uPA receptor -like)|rcsb pdb:7BPR|reactome:R-HSA-163125|refseq:NP_001123483.1|refseq:NP_113639.4 refseq:NP_002047.2|refseq:NP_001231639.1|ensembl:ENSG00000198380(gene)|ensembl:ENST00000357308(transcript)|go:"GO:0004360"("glutamine-fructose-6-phosphate transaminase (isomerizing) activity")|go:"GO:0005829"(cytosol)|go:"GO:0006002"(fructose 6-phosphate metabolic process)|go:"GO:0006047"(UDP-N-acetylglucosamine metabolic process)|go:"GO:0006048"(UDP-N-acetylglucosamine biosynthetic process)|go:"GO:0006112"(energy reserve metabolic process)|go:"GO:0006487"(protein N-linked glycosylation)|go:"GO:0006541"(glutamine metabolic process)|go:"GO:0032922"(circadian regulation of gene expression)|go:"GO:0070062"(extracellular exosome)|go:"GO:0097367"(carbohydrate derivative binding)|interpro:IPR001347("Sugar isomerase (SIS)")|interpro:IPR005855(Glucosamine-fructose-6-phosphate aminotransferase, isomerising)|interpro:IPR017932|interpro:IPR029055|interpro:IPR035466|interpro:IPR035490|mint:Q06210|rcsb pdb:2V4M|rcsb pdb:2ZJ3|rcsb pdb:2ZJ4|rcsb pdb:6R4E|rcsb pdb:6R4F|rcsb pdb:6R4G|rcsb pdb:6R4H|rcsb pdb:6R4I|rcsb pdb:6R4J|rcsb pdb:6SVM|rcsb pdb:6SVO|rcsb pdb:6SVP|rcsb pdb:6SVQ|rcsb pdb:6ZMJ|rcsb pdb:6ZMK|rcsb pdb:7NDL|reactome:R-HSA-381038|reactome:R-HSA-4085023|reactome:R-HSA-446210 - - - figure legend:Supp Table S4 and Supp Fig. S3|comment:"Coimmunoprecipitation with 34ED229 (T2) anti-TEX101 antibody"|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-testis)|taxid:9606(Homo sapiens) - 2020/03/24 2020/06/18 rogid:ZE4tXTFi7lUCcIbCL4KHzY3a6xM9606 rogid:fP9V7Qv/Wv8EaxMa0lrY4icjCno9606 rigid:2wTqH12DHkSLcixvnxiJPZhqAc0 false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9BY14 uniprotkb:P05090 intact:EBI-12549378|ensembl:ENSP00000472769|uniprotkb:Q7L5R2|uniprotkb:Q9BPY7 intact:EBI-715495|uniprotkb:Q6IBG6|uniprotkb:B2R579|uniprotkb:D3DNW6|ensembl:ENSP00000345179 psi-mi:tx101_human(display_long)|uniprotkb:TEX101(gene name)|psi-mi:TEX101(display_short)|uniprotkb:Cell surface receptor NYD-SP8(gene name synonym)|uniprotkb:SGRG(gene name synonym)|uniprotkb:Scleroderma-associated autoantigen(gene name synonym)|uniprotkb:Spermatogenesis-related gene protein(gene name synonym)|uniprotkb:UNQ867/PRO1884(orf name) psi-mi:apod_human(display_long)|uniprotkb:APOD(gene name)|psi-mi:APOD(display_short) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Schiza et al. (2018) imex:IM-28077|pubmed:30097533 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-25504841|imex:IM-28077-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000131126(gene)|ensembl:ENST00000598265(transcript)|go:"GO:0001669"(acrosomal vesicle)|go:"GO:0002080"(acrosomal membrane)|go:"GO:0005576"(extracellular region)|go:"GO:0005886"(plasma membrane)|go:"GO:0007339"(binding of sperm to zona pellucida)|go:"GO:0009566"(fertilization)|go:"GO:0030317"(flagellated sperm motility)|go:"GO:0044853"(plasma membrane raft)|go:"GO:0046658"(anchored component of plasma membrane)|go:"GO:1901317"(regulation of flagellated sperm motility)|interpro:IPR016054(Ly-6 antigen / uPA receptor -like)|rcsb pdb:7BPR|reactome:R-HSA-163125|refseq:NP_001123483.1|refseq:NP_113639.4 refseq:NP_001638.1|go:"GO:0022626"(cytosolic ribosome)|go:"GO:0030425"(dendrite)|go:"GO:0042246"(tissue regeneration)|go:"GO:0042308"(negative regulation of protein import into nucleus)|go:"GO:0042493"|go:"GO:0043025"(neuronal cell body)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0048662"(negative regulation of smooth muscle cell proliferation)|go:"GO:0048678"(response to axon injury)|go:"GO:0051895"(negative regulation of focal adhesion assembly)|go:"GO:0060588"(negative regulation of lipoprotein lipid oxidation)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071638"(negative regulation of monocyte chemotactic protein-1 production)|go:"GO:1900016"(negative regulation of cytokine production involved in inflammatory response)|go:"GO:2000098"(negative regulation of smooth muscle cell-matrix adhesion)|go:"GO:2000405"(negative regulation of T cell migration)|interpro:IPR000566(Lipocalin-related protein and Bos/Can/Equ allergen)|interpro:IPR002969(Apolipoprotein D)|interpro:IPR012674(Calycin)|interpro:IPR022271|interpro:IPR022272|interpro:IPR026222|mint:P05090|rcsb pdb:2APD|rcsb pdb:2HZQ|rcsb pdb:2HZR|reactome:R-HSA-804914|reactome:R-HSA-9029569|go:"GO:0006006"(glucose metabolic process)|go:"GO:0006629"(lipid metabolic process)|go:"GO:0007420"(brain development)|go:"GO:0007568"(aging)|go:"GO:0010642"(negative regulation of platelet-derived growth factor receptor signaling pathway)|go:"GO:0014012"(peripheral nervous system axon regeneration)|go:"GO:0015485"(cholesterol binding)|ensembl:ENSG00000189058(gene)|ensembl:ENST00000343267(transcript)|go:"GO:0000302"(response to reactive oxygen species)|go:"GO:0001525"(angiogenesis)|go:"GO:0005319"(lipid transporter activity)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum) - - - figure legend:Supp Table S4 and Supp Fig. S3|comment:"Coimmunoprecipitation with 34ED229 (T2) anti-TEX101 antibody"|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-testis)|taxid:9606(Homo sapiens) - 2020/03/24 2020/06/18 rogid:ZE4tXTFi7lUCcIbCL4KHzY3a6xM9606 rogid:eD7+u5/ZQ5vntlwrq6itkhCxZJU9606 rigid:2wTqH12DHkSLcixvnxiJPZhqAc0 false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9BY14 uniprotkb:P04406 intact:EBI-12549378|ensembl:ENSP00000472769|uniprotkb:Q7L5R2|uniprotkb:Q9BPY7 intact:EBI-354056|uniprotkb:P00354|uniprotkb:Q53X65|uniprotkb:E7EUT4|ensembl:ENSP00000229239|ensembl:ENSP00000380068|ensembl:ENSP00000380070 psi-mi:tx101_human(display_long)|uniprotkb:TEX101(gene name)|psi-mi:TEX101(display_short)|uniprotkb:Cell surface receptor NYD-SP8(gene name synonym)|uniprotkb:SGRG(gene name synonym)|uniprotkb:Scleroderma-associated autoantigen(gene name synonym)|uniprotkb:Spermatogenesis-related gene protein(gene name synonym)|uniprotkb:UNQ867/PRO1884(orf name) psi-mi:g3p_human(display_long)|uniprotkb:GAPDH(gene name)|psi-mi:GAPDH(display_short)|uniprotkb:OK/SW-cl.12(orf name)|uniprotkb:CDABP0047(orf name)|uniprotkb:GAPD(gene name synonym)|uniprotkb:Peptidyl-cysteine S-nitrosylase GAPDH(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Schiza et al. (2018) imex:IM-28077|pubmed:30097533 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-25504841|imex:IM-28077-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000131126(gene)|ensembl:ENST00000598265(transcript)|go:"GO:0001669"(acrosomal vesicle)|go:"GO:0002080"(acrosomal membrane)|go:"GO:0005576"(extracellular region)|go:"GO:0005886"(plasma membrane)|go:"GO:0007339"(binding of sperm to zona pellucida)|go:"GO:0009566"(fertilization)|go:"GO:0030317"(flagellated sperm motility)|go:"GO:0044853"(plasma membrane raft)|go:"GO:0046658"(anchored component of plasma membrane)|go:"GO:1901317"(regulation of flagellated sperm motility)|interpro:IPR016054(Ly-6 antigen / uPA receptor -like)|rcsb pdb:7BPR|reactome:R-HSA-163125|refseq:NP_001123483.1|refseq:NP_113639.4 refseq:NP_002037.2|refseq:NP_001243728.1|refseq:NP_001276674.1|refseq:NP_001276675.1|dip:DIP-32521N|go:"GO:0031965"(nuclear membrane)|go:"GO:0031982"(vesicle)|go:"GO:0032481"(positive regulation of type I interferon production)|go:"GO:0035605"(peptidyl-cysteine S-nitrosylase activity)|go:"GO:0035606"(peptidyl-cysteine S-trans-nitrosylation)|go:"GO:0042802"(identical protein binding)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0050661"(NADP binding)|go:"GO:0050821"(protein stabilization)|go:"GO:0050832"(defense response to fungus)|go:"GO:0051287"(NAD binding)|go:"GO:0051402"(neuron apoptotic process)|go:"GO:0051873"(killing by host of symbiont cells)|go:"GO:0061844"(antimicrobial humoral immune response mediated by antimicrobial peptide)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071346"(cellular response to interferon-gamma)|go:"GO:0097452"(GAIT complex)|go:"GO:0097718"(disordered domain specific binding)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR006424(Glyceraldehyde-3-phosphate dehydrogenase, type I)|interpro:IPR020828|interpro:IPR020829|interpro:IPR020830|interpro:IPR020831|interpro:IPR036291|mint:P04406|rcsb pdb:1U8F|rcsb pdb:1ZNQ|rcsb pdb:2FEH|rcsb pdb:3GPD|rcsb pdb:4WNC|rcsb pdb:4WNI|rcsb pdb:6ADE|rcsb pdb:6M61|rcsb pdb:6YND|rcsb pdb:6YNE|rcsb pdb:6YNF|rcsb pdb:6YNH|reactome:R-HSA-70171|reactome:R-HSA-70263|rcsb pdb:6IQ6|ensembl:ENSG00000111640(gene)|ensembl:ENST00000229239(transcript)|ensembl:ENST00000396859(transcript)|ensembl:ENST00000396861(transcript)|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0001819"(positive regulation of cytokine production)|go:"GO:0004365"("glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity")|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005811"(lipid droplet)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006006"(glucose metabolic process)|go:"GO:0006096"(glycolytic process)|go:"GO:0008017"(microtubule binding)|go:"GO:0010951"(negative regulation of endopeptidase activity)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0016020"(membrane)|go:"GO:0016241"(regulation of macroautophagy)|go:"GO:0017148"(negative regulation of translation)|go:"GO:0019828"(aspartic-type endopeptidase inhibitor activity)|go:"GO:0031640"(killing of cells of another organism) - - - figure legend:Supp Table S4 and Supp Fig. S3|comment:"Coimmunoprecipitation with 34ED229 (T2) anti-TEX101 antibody"|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-testis)|taxid:9606(Homo sapiens) - 2020/03/24 2020/06/18 rogid:ZE4tXTFi7lUCcIbCL4KHzY3a6xM9606 rogid:9YENN/dfKl/d0tJtfFyQp2o8eAc9606 rigid:2wTqH12DHkSLcixvnxiJPZhqAc0 false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9BY14 uniprotkb:Q9H8H3 intact:EBI-12549378|ensembl:ENSP00000472769|uniprotkb:Q7L5R2|uniprotkb:Q9BPY7 intact:EBI-1390168|uniprotkb:Q9H7R3|uniprotkb:Q9UHZ7|uniprotkb:Q9Y422|ensembl:ENSP00000331787|ensembl:ENSP00000447542|ensembl:ENSP00000448785 psi-mi:tx101_human(display_long)|uniprotkb:TEX101(gene name)|psi-mi:TEX101(display_short)|uniprotkb:Cell surface receptor NYD-SP8(gene name synonym)|uniprotkb:SGRG(gene name synonym)|uniprotkb:Scleroderma-associated autoantigen(gene name synonym)|uniprotkb:Spermatogenesis-related gene protein(gene name synonym)|uniprotkb:UNQ867/PRO1884(orf name) psi-mi:met7a_human(display_long)|uniprotkb:Protein AAM-B(gene name synonym)|uniprotkb:METTL7A(gene name)|psi-mi:METTL7A(display_short)|uniprotkb:PRO0066(orf name)|uniprotkb:UNQ1902/PRO4348(orf name) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Schiza et al. (2018) imex:IM-28077|pubmed:30097533 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-25504841|imex:IM-28077-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000131126(gene)|ensembl:ENST00000598265(transcript)|go:"GO:0001669"(acrosomal vesicle)|go:"GO:0002080"(acrosomal membrane)|go:"GO:0005576"(extracellular region)|go:"GO:0005886"(plasma membrane)|go:"GO:0007339"(binding of sperm to zona pellucida)|go:"GO:0009566"(fertilization)|go:"GO:0030317"(flagellated sperm motility)|go:"GO:0044853"(plasma membrane raft)|go:"GO:0046658"(anchored component of plasma membrane)|go:"GO:1901317"(regulation of flagellated sperm motility)|interpro:IPR016054(Ly-6 antigen / uPA receptor -like)|rcsb pdb:7BPR|reactome:R-HSA-163125|refseq:NP_001123483.1|refseq:NP_113639.4 refseq:NP_054752.3|refseq:XP_006719395.1|ensembl:ENSG00000185432(gene)|ensembl:ENST00000332160(transcript)|ensembl:ENST00000547104(transcript)|ensembl:ENST00000548553(transcript)|go:"GO:0005576"(extracellular region)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005811"(lipid droplet)|go:"GO:0008168"(methyltransferase activity)|go:"GO:0016020"(membrane)|go:"GO:0032259"(methylation)|go:"GO:1904724"(tertiary granule lumen)|interpro:IPR013216(Methyltransferase type 11)|interpro:IPR029063|mint:Q9H8H3|reactome:R-HSA-6798695 - - - figure legend:Supp Table S4 and Supp Fig. S3|comment:"Coimmunoprecipitation with 34ED229 (T2) anti-TEX101 antibody"|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-testis)|taxid:9606(Homo sapiens) - 2020/03/24 2020/06/18 rogid:ZE4tXTFi7lUCcIbCL4KHzY3a6xM9606 rogid:b8PnE+BClVn1MzOlg0uIaqDSOaU9606 rigid:2wTqH12DHkSLcixvnxiJPZhqAc0 false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9BY14 uniprotkb:O14773 intact:EBI-12549378|ensembl:ENSP00000472769|uniprotkb:Q7L5R2|uniprotkb:Q9BPY7 intact:EBI-2800203|uniprotkb:Q5JAK6|uniprotkb:Q6UX56|uniprotkb:Q96C37|uniprotkb:Q71JP6|uniprotkb:Q53HT1|ensembl:ENSP00000299427 psi-mi:tx101_human(display_long)|uniprotkb:TEX101(gene name)|psi-mi:TEX101(display_short)|uniprotkb:Cell surface receptor NYD-SP8(gene name synonym)|uniprotkb:SGRG(gene name synonym)|uniprotkb:Scleroderma-associated autoantigen(gene name synonym)|uniprotkb:Spermatogenesis-related gene protein(gene name synonym)|uniprotkb:UNQ867/PRO1884(orf name) psi-mi:tpp1_human(display_long)|uniprotkb:CLN2(gene name synonym)|uniprotkb:Tripeptidyl-peptidase I(gene name synonym)|uniprotkb:Tripeptidyl aminopeptidase(gene name synonym)|uniprotkb:Lysosomal pepstatin-insensitive protease(gene name synonym)|uniprotkb:Cell growth-inhibiting gene 1 protein(gene name synonym)|uniprotkb:GIG1(orf name)|uniprotkb:UNQ267/PRO304(orf name)|uniprotkb:TPP1(gene name)|psi-mi:TPP1(display_short) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Schiza et al. (2018) imex:IM-28077|pubmed:30097533 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-25504841|imex:IM-28077-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000131126(gene)|ensembl:ENST00000598265(transcript)|go:"GO:0001669"(acrosomal vesicle)|go:"GO:0002080"(acrosomal membrane)|go:"GO:0005576"(extracellular region)|go:"GO:0005886"(plasma membrane)|go:"GO:0007339"(binding of sperm to zona pellucida)|go:"GO:0009566"(fertilization)|go:"GO:0030317"(flagellated sperm motility)|go:"GO:0044853"(plasma membrane raft)|go:"GO:0046658"(anchored component of plasma membrane)|go:"GO:1901317"(regulation of flagellated sperm motility)|interpro:IPR016054(Ly-6 antigen / uPA receptor -like)|rcsb pdb:7BPR|reactome:R-HSA-163125|refseq:NP_001123483.1|refseq:NP_113639.4 refseq:NP_000382.3|ensembl:ENSG00000166340(gene)|ensembl:ENST00000299427(transcript)|go:"GO:0004175"(endopeptidase activity)|go:"GO:0004252"(serine-type endopeptidase activity)|go:"GO:0005764"(lysosome)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0006508"(proteolysis)|go:"GO:0006629"(lipid metabolic process)|go:"GO:0007040"(lysosome organization)|go:"GO:0007399"(nervous system development)|go:"GO:0007417"(central nervous system development)|go:"GO:0008233"(peptidase activity)|go:"GO:0008236"(serine-type peptidase activity)|go:"GO:0008240"(tripeptidyl-peptidase activity)|go:"GO:0030163"(protein catabolic process)|go:"GO:0030855"(epithelial cell differentiation)|go:"GO:0035727"(lysophosphatidic acid binding)|go:"GO:0042277"(peptide binding)|go:"GO:0042470"(melanosome)|go:"GO:0043171"(peptide catabolic process)|go:"GO:0043202"(lysosomal lumen)|go:"GO:0045121"(membrane raft)|go:"GO:0045453"(bone resorption)|go:"GO:0046872"(metal ion binding)|go:"GO:0050885"(neuromuscular process controlling balance)|go:"GO:0055037"(recycling endosome)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070198"(protein localization to chromosome, telomeric region)|go:"GO:0120146"(sulfatide binding)|go:"GO:1905146"(lysosomal protein catabolic process)|interpro:IPR015366(Peptidase S53, propeptide)|interpro:IPR030400|interpro:IPR036852|mint:O14773|rcsb pdb:1R60|rcsb pdb:3EDY|rcsb pdb:3EE6|reactome:R-HSA-381038|interpro:IPR000209(Peptidase S8 and S53, subtilisin, kexin, sedolisin)|dip:DIP-47434N - - - figure legend:Supp Table S4 and Supp Fig. S3|comment:"Coimmunoprecipitation with 34ED229 (T2) anti-TEX101 antibody"|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-testis)|taxid:9606(Homo sapiens) - 2020/03/24 2020/06/18 rogid:ZE4tXTFi7lUCcIbCL4KHzY3a6xM9606 rogid:lhbu2VS1TqFCwSf8XBd6U17K1sU9606 rigid:2wTqH12DHkSLcixvnxiJPZhqAc0 false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9BY14 uniprotkb:P53396 intact:EBI-12549378|ensembl:ENSP00000472769|uniprotkb:Q7L5R2|uniprotkb:Q9BPY7 intact:EBI-1042794|uniprotkb:Q13037|uniprotkb:Q9BRL0|uniprotkb:B4E3P0|uniprotkb:B4DIM0|ensembl:ENSP00000253792|ensembl:ENSP00000466259 psi-mi:tx101_human(display_long)|uniprotkb:TEX101(gene name)|psi-mi:TEX101(display_short)|uniprotkb:Cell surface receptor NYD-SP8(gene name synonym)|uniprotkb:SGRG(gene name synonym)|uniprotkb:Scleroderma-associated autoantigen(gene name synonym)|uniprotkb:Spermatogenesis-related gene protein(gene name synonym)|uniprotkb:UNQ867/PRO1884(orf name) psi-mi:acly_human(display_long)|uniprotkb:ACLY(gene name)|psi-mi:ACLY(display_short)|uniprotkb:"ATP-citrate (pro-S-)-lyase"(gene name synonym)|uniprotkb:Citrate cleavage enzyme(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Schiza et al. (2018) imex:IM-28077|pubmed:30097533 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-25504841|imex:IM-28077-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000131126(gene)|ensembl:ENST00000598265(transcript)|go:"GO:0001669"(acrosomal vesicle)|go:"GO:0002080"(acrosomal membrane)|go:"GO:0005576"(extracellular region)|go:"GO:0005886"(plasma membrane)|go:"GO:0007339"(binding of sperm to zona pellucida)|go:"GO:0009566"(fertilization)|go:"GO:0030317"(flagellated sperm motility)|go:"GO:0044853"(plasma membrane raft)|go:"GO:0046658"(anchored component of plasma membrane)|go:"GO:1901317"(regulation of flagellated sperm motility)|interpro:IPR016054(Ly-6 antigen / uPA receptor -like)|rcsb pdb:7BPR|reactome:R-HSA-163125|refseq:NP_001123483.1|refseq:NP_113639.4 refseq:NP_001087.2|refseq:NP_942127.1|go:"GO:0070062"(extracellular exosome)|go:"GO:1904813"(ficolin-1-rich granule lumen)|interpro:IPR002020(Citrate synthase-like)|interpro:IPR003781(CoA-binding)|interpro:IPR005811(ATP-citrate lyase/succinyl-CoA ligase)|interpro:IPR014608(ATP-citrate synthase)|ensembl:ENSG00000131473(gene)|ensembl:ENST00000352035(transcript)|ensembl:ENST00000590151(transcript)|go:"GO:0003878"(ATP citrate synthase activity)|interpro:IPR016102(Succinyl-CoA synthetase-like)|go:"GO:0005524"(ATP binding)|interpro:IPR016143(Citrate synthase-like, small alpha subdomain)|interpro:IPR017440(ATP-citrate lyase/succinyl-CoA ligase, active site)|interpro:IPR017866|interpro:IPR032263|go:"GO:0005576"(extracellular region)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006085"(acetyl-CoA biosynthetic process)|go:"GO:0006101"(citrate metabolic process)|go:"GO:0006107"(oxaloacetate metabolic process)|go:"GO:0006633"(fatty acid biosynthetic process)|go:"GO:0006695"(cholesterol biosynthetic process)|go:"GO:0008610"(lipid biosynthetic process)|go:"GO:0015936"(coenzyme A metabolic process)|go:"GO:0016020"(membrane)|go:"GO:0035578"(azurophil granule lumen)|go:"GO:0046872"(metal ion binding)|interpro:IPR033847|rcsb pdb:6O0H|interpro:IPR036291|rcsb pdb:6POE|interpro:IPR036969|rcsb pdb:6POF|rcsb pdb:6QFB|mint:P53396|rcsb pdb:6UI9|rcsb pdb:6UIA|rcsb pdb:3MWD|rcsb pdb:6UUW|rcsb pdb:6UUZ|rcsb pdb:6UV5|rcsb pdb:6Z2H|rcsb pdb:7LIW|rcsb pdb:7LJ9|rcsb pdb:7LLA|reactome:R-HSA-163765|rcsb pdb:3MWE|reactome:R-HSA-6798695|reactome:R-HSA-75105|rcsb pdb:3PFF|rcsb pdb:5TDE|rcsb pdb:5TDF|rcsb pdb:5TDM|rcsb pdb:5TDZ|rcsb pdb:5TE1|rcsb pdb:5TEQ|rcsb pdb:5TES|rcsb pdb:5TET|rcsb pdb:6HXH|rcsb pdb:6HXK|rcsb pdb:6HXL|rcsb pdb:6HXM|refseq:XP_005257452.1|refseq:NP_001290203.1|refseq:NP_001290204.1 - - - figure legend:Supp Table S4 and Supp Fig. S3|comment:"Coimmunoprecipitation with 34ED229 (T2) anti-TEX101 antibody"|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-testis)|taxid:9606(Homo sapiens) - 2020/03/24 2020/06/18 rogid:ZE4tXTFi7lUCcIbCL4KHzY3a6xM9606 rogid:NaxO5aRi08GTrEV9aIboUdTlpAs9606 rigid:2wTqH12DHkSLcixvnxiJPZhqAc0 false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9BY14 uniprotkb:P07864 intact:EBI-12549378|ensembl:ENSP00000472769|uniprotkb:Q7L5R2|uniprotkb:Q9BPY7 intact:EBI-21716174|uniprotkb:D3DQY4|uniprotkb:Q6GSG8|uniprotkb:Q7Z7J4|ensembl:ENSP00000280704|ensembl:ENSP00000437783 psi-mi:tx101_human(display_long)|uniprotkb:TEX101(gene name)|psi-mi:TEX101(display_short)|uniprotkb:Cell surface receptor NYD-SP8(gene name synonym)|uniprotkb:SGRG(gene name synonym)|uniprotkb:Scleroderma-associated autoantigen(gene name synonym)|uniprotkb:Spermatogenesis-related gene protein(gene name synonym)|uniprotkb:UNQ867/PRO1884(orf name) psi-mi:ldhc_human(display_long)|uniprotkb:Cancer/testis antigen 32(gene name synonym)|uniprotkb:LDH testis subunit(gene name synonym)|uniprotkb:LDH-X(gene name synonym)|uniprotkb:LDHC(gene name)|psi-mi:LDHC(display_short)|uniprotkb:LDH3(gene name synonym)|uniprotkb:LDHX(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Schiza et al. (2018) imex:IM-28077|pubmed:30097533 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-25504841|imex:IM-28077-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000131126(gene)|ensembl:ENST00000598265(transcript)|go:"GO:0001669"(acrosomal vesicle)|go:"GO:0002080"(acrosomal membrane)|go:"GO:0005576"(extracellular region)|go:"GO:0005886"(plasma membrane)|go:"GO:0007339"(binding of sperm to zona pellucida)|go:"GO:0009566"(fertilization)|go:"GO:0030317"(flagellated sperm motility)|go:"GO:0044853"(plasma membrane raft)|go:"GO:0046658"(anchored component of plasma membrane)|go:"GO:1901317"(regulation of flagellated sperm motility)|interpro:IPR016054(Ly-6 antigen / uPA receptor -like)|rcsb pdb:7BPR|reactome:R-HSA-163125|refseq:NP_001123483.1|refseq:NP_113639.4 refseq:NP_002292.1|refseq:NP_059144.1|go:"GO:0030317"(flagellated sperm motility)|go:"GO:0031514"(motile cilium)|go:"GO:0070062"(extracellular exosome)|interpro:IPR001236(Lactate/malate dehydrogenase)|interpro:IPR001557(L-lactate/malate dehydrogenase)|interpro:IPR011304(L-lactate dehydrogenase)|interpro:IPR015955(Lactate dehydrogenase/glycoside hydrolase, family 4, C-terminal)|interpro:IPR018177|interpro:IPR022383|interpro:IPR036291|reactome:R-HSA-70268|ensembl:ENSG00000166796(gene)|ensembl:ENST00000280704(transcript)|ensembl:ENST00000541669(transcript)|go:"GO:0004459"(L-lactate dehydrogenase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0005975"(carbohydrate metabolic process)|go:"GO:0006754"(ATP biosynthetic process)|go:"GO:0019244"(lactate biosynthetic process from pyruvate)|go:"GO:0019516"(lactate oxidation) - - - figure legend:Supp Table S4 and Supp Fig. S3|comment:"Coimmunoprecipitation with 34ED229 (T2) anti-TEX101 antibody"|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-testis)|taxid:9606(Homo sapiens) - 2020/03/24 2020/06/18 rogid:ZE4tXTFi7lUCcIbCL4KHzY3a6xM9606 rogid:Q8SOlZeihuMeWgII7Thdv8wSwn09606 rigid:2wTqH12DHkSLcixvnxiJPZhqAc0 false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9BY14 uniprotkb:Q9Y3Z3 intact:EBI-12549378|ensembl:ENSP00000472769|uniprotkb:Q7L5R2|uniprotkb:Q9BPY7 intact:EBI-1054601|uniprotkb:Q5JXG8|uniprotkb:Q9H004|uniprotkb:Q9H005|uniprotkb:Q9H3U9|uniprotkb:B4E2A5|uniprotkb:Q8N491|uniprotkb:E1P5V2|ensembl:ENSP00000493536|ensembl:ENSP00000495667|ensembl:ENSP00000506877|ensembl:ENSP00000507178 psi-mi:tx101_human(display_long)|uniprotkb:TEX101(gene name)|psi-mi:TEX101(display_short)|uniprotkb:Cell surface receptor NYD-SP8(gene name synonym)|uniprotkb:SGRG(gene name synonym)|uniprotkb:Scleroderma-associated autoantigen(gene name synonym)|uniprotkb:Spermatogenesis-related gene protein(gene name synonym)|uniprotkb:UNQ867/PRO1884(orf name) psi-mi:samh1_human(display_long)|uniprotkb:Dendritic cell-derived IFNG-induced protein(gene name synonym)|uniprotkb:Monocyte protein 5(gene name synonym)|uniprotkb:SAMHD1(gene name)|psi-mi:SAMHD1(display_short)|uniprotkb:MOP5(gene name synonym)|uniprotkb:SAM domain and HD domain-containing protein 1(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Schiza et al. (2018) imex:IM-28077|pubmed:30097533 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-25504841|imex:IM-28077-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000131126(gene)|ensembl:ENST00000598265(transcript)|go:"GO:0001669"(acrosomal vesicle)|go:"GO:0002080"(acrosomal membrane)|go:"GO:0005576"(extracellular region)|go:"GO:0005886"(plasma membrane)|go:"GO:0007339"(binding of sperm to zona pellucida)|go:"GO:0009566"(fertilization)|go:"GO:0030317"(flagellated sperm motility)|go:"GO:0044853"(plasma membrane raft)|go:"GO:0046658"(anchored component of plasma membrane)|go:"GO:1901317"(regulation of flagellated sperm motility)|interpro:IPR016054(Ly-6 antigen / uPA receptor -like)|rcsb pdb:7BPR|reactome:R-HSA-163125|refseq:NP_001123483.1|refseq:NP_113639.4 refseq:NP_056289.2|refseq:XP_005260441.1|ensembl:ENSG00000101347(gene)|ensembl:ENST00000646673(transcript)|ensembl:ENST00000646869(transcript)|ensembl:ENST00000683766(transcript)|go:"GO:0000724"(double-strand break repair via homologous recombination)|go:"GO:0003676"(nucleic acid binding)|ensembl:ENST00000682773(transcript)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0004540"(ribonuclease activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0006203"(dGTP catabolic process)|go:"GO:0006955"(immune response)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0008270"(zinc ion binding)|go:"GO:0008832"(dGTPase activity)|go:"GO:0009264"(deoxyribonucleotide catabolic process)|go:"GO:0016446"(somatic hypermutation of immunoglobulin genes)|go:"GO:0016793"(triphosphoric monoester hydrolase activity)|go:"GO:0032567"(dGTP binding)|go:"GO:0035861"(site of double-strand break)|go:"GO:0042802"(identical protein binding)|go:"GO:0045087"(innate immune response)|go:"GO:0045088"(regulation of innate immune response)|go:"GO:0046061"(dATP catabolic process)|go:"GO:0051289"(protein homotetramerization)|go:"GO:0051607"(defense response to virus)|go:"GO:0060339"(negative regulation of type I interferon-mediated signaling pathway)|go:"GO:0097197"(tetraspanin-enriched microdomain)|go:"GO:0106375"(deoxynucleoside triphosphate hydrolase activity)|go:"GO:0110025"(DNA strand resection involved in replication fork processing)|interpro:IPR001660(Sterile alpha motif SAM)|interpro:IPR003607(Metal-dependent phosphohydrolase, HD region)|interpro:IPR006674(Metal-dependent phosphohydrolase, HD region, subdomain)|interpro:IPR013761(Sterile alpha motif-type)|mint:Q9Y3Z3|rcsb pdb:2E8O|rcsb pdb:3U1N|rcsb pdb:4BZB|rcsb pdb:4BZC|rcsb pdb:4CC9|rcsb pdb:4MZ7|rcsb pdb:4Q7H|rcsb pdb:4QFX|rcsb pdb:4QFY|rcsb pdb:4QFZ|rcsb pdb:4QG0|rcsb pdb:4QG1|rcsb pdb:4QG2|rcsb pdb:4QG4|rcsb pdb:4RXO|rcsb pdb:4RXP|rcsb pdb:4RXQ|rcsb pdb:4RXR|rcsb pdb:4RXS|rcsb pdb:4TNP|rcsb pdb:4TNQ|rcsb pdb:4TNR|rcsb pdb:4TNX|rcsb pdb:4TNY|rcsb pdb:4TNZ|rcsb pdb:4TO0|rcsb pdb:4TO1|rcsb pdb:4TO2|rcsb pdb:4TO3|rcsb pdb:4TO4|rcsb pdb:4TO5|rcsb pdb:6DW4|rcsb pdb:6DW5|rcsb pdb:6DW7|rcsb pdb:6DWD|rcsb pdb:6DWJ|rcsb pdb:6DWK|rcsb pdb:6TX0|rcsb pdb:6TXA|rcsb pdb:6TXC|rcsb pdb:6TXE|rcsb pdb:6TXF|rcsb pdb:6U6X|rcsb pdb:6U6Y|rcsb pdb:6U6Z|rcsb pdb:6XU1|rcsb pdb:6YOM|rcsb pdb:7A5Y|reactome:R-HSA-8956319|rcsb pdb:4TO6|rcsb pdb:4ZWE|reactome:R-HSA-909733|rcsb pdb:4ZWG|rcsb pdb:5AO0|rcsb pdb:5AO1|rcsb pdb:5AO2|rcsb pdb:5AO3|rcsb pdb:5AO4|rcsb pdb:6CM2|rcsb pdb:6DW3|dip:DIP-50704N - - - figure legend:Supp Table S4 and Supp Fig. S3|comment:"Coimmunoprecipitation with 34ED229 (T2) anti-TEX101 antibody"|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-testis)|taxid:9606(Homo sapiens) - 2020/03/24 2020/06/18 rogid:ZE4tXTFi7lUCcIbCL4KHzY3a6xM9606 rogid:cxoMHFueO9JuBg2d0PoGCYoOwY09606 rigid:2wTqH12DHkSLcixvnxiJPZhqAc0 false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9BY14 uniprotkb:Q15392 intact:EBI-12549378|ensembl:ENSP00000472769|uniprotkb:Q7L5R2|uniprotkb:Q9BPY7 intact:EBI-5457558|uniprotkb:B7Z817|ensembl:ENSP00000360316|ensembl:ENSP00000416585|uniprotkb:D3DQ51|uniprotkb:Q9HBA8|intact:EBI-10964490 psi-mi:tx101_human(display_long)|uniprotkb:TEX101(gene name)|psi-mi:TEX101(display_short)|uniprotkb:Cell surface receptor NYD-SP8(gene name synonym)|uniprotkb:SGRG(gene name synonym)|uniprotkb:Scleroderma-associated autoantigen(gene name synonym)|uniprotkb:Spermatogenesis-related gene protein(gene name synonym)|uniprotkb:UNQ867/PRO1884(orf name) psi-mi:dhc24_human(display_long)|uniprotkb:DHCR24(gene name)|psi-mi:DHCR24(display_short)|uniprotkb:KIAA0018(gene name synonym)|uniprotkb:24-dehydrocholesterol reductase(gene name synonym)|uniprotkb:Diminuto/dwarf1 homolog(gene name synonym)|uniprotkb:Seladin-1(gene name synonym)|uniprotkb:3-beta-hydroxysterol Delta-24-reductase(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Schiza et al. (2018) imex:IM-28077|pubmed:30097533 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-25504841|imex:IM-28077-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000131126(gene)|ensembl:ENST00000598265(transcript)|go:"GO:0001669"(acrosomal vesicle)|go:"GO:0002080"(acrosomal membrane)|go:"GO:0005576"(extracellular region)|go:"GO:0005886"(plasma membrane)|go:"GO:0007339"(binding of sperm to zona pellucida)|go:"GO:0009566"(fertilization)|go:"GO:0030317"(flagellated sperm motility)|go:"GO:0044853"(plasma membrane raft)|go:"GO:0046658"(anchored component of plasma membrane)|go:"GO:1901317"(regulation of flagellated sperm motility)|interpro:IPR016054(Ly-6 antigen / uPA receptor -like)|rcsb pdb:7BPR|reactome:R-HSA-163125|refseq:NP_001123483.1|refseq:NP_113639.4 ensembl:ENSG00000116133(gene)|ensembl:ENST00000371269(transcript)|ensembl:ENST00000436604(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0000246"("delta24(24-1) sterol reductase activity")|go:"GO:0005634"(nucleus)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0006695"(cholesterol biosynthetic process)|go:"GO:0006915"(apoptotic process)|go:"GO:0006979"(response to oxidative stress)|go:"GO:0007265"(Ras protein signal transduction)|go:"GO:0008104"(protein localization)|go:"GO:0008202"(steroid metabolic process)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0009725"(response to hormone)|go:"GO:0009888"(tissue development)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016628"(oxidoreductase activity, acting on the CH-CH group of donors, NAD or NADP as acceptor)|go:"GO:0019899"(enzyme binding)|go:"GO:0030539"(male genitalia development)|go:"GO:0031639"(plasminogen activation)|go:"GO:0033489"(cholesterol biosynthetic process via desmosterol)|go:"GO:0033490"(cholesterol biosynthetic process via lathosterol)|go:"GO:0042605"(peptide antigen binding)|go:"GO:0042987"(amyloid precursor protein catabolic process)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043154"(negative regulation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0043588"(skin development)|go:"GO:0050614"(delta24-sterol reductase activity)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0061024"(membrane organization)|go:"GO:0071949"(FAD binding)|go:"GO:1901214"(regulation of neuron death)|interpro:IPR006094(FAD linked oxidase, N-terminal)|interpro:IPR016166(FAD-binding, type 2)|interpro:IPR016169(CO dehydrogenase flavoprotein-like, FAD-binding, subdomain 2)|interpro:IPR036318|interpro:IPR040165|go:"GO:0005737"(cytoplasm)|mint:Q15392|reactome:R-HSA-6807047|reactome:R-HSA-6807062|refseq:NP_055577.1 - - - figure legend:Supp Table S4 and Supp Fig. S3|comment:"Coimmunoprecipitation with 34ED229 (T2) anti-TEX101 antibody"|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-testis)|taxid:9606(Homo sapiens) - 2020/03/24 2020/06/18 rogid:ZE4tXTFi7lUCcIbCL4KHzY3a6xM9606 rogid:kg8bxZHxFFTUmvP9UQMeVFRNWQM9606 rigid:2wTqH12DHkSLcixvnxiJPZhqAc0 false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9BY14 uniprotkb:Q8N163 intact:EBI-12549378|ensembl:ENSP00000472769|uniprotkb:Q7L5R2|uniprotkb:Q9BPY7 intact:EBI-355410|uniprotkb:A6NL03|uniprotkb:Q6P0Q9|uniprotkb:Q8N3G7|uniprotkb:Q8N8M1|uniprotkb:Q8TF34|uniprotkb:Q9H9Q9|uniprotkb:Q9HD12|uniprotkb:Q9NT55|ensembl:ENSP00000310670|ensembl:ENSP00000373930|uniprotkb:B2RB79|uniprotkb:D3DSR6 psi-mi:tx101_human(display_long)|uniprotkb:TEX101(gene name)|psi-mi:TEX101(display_short)|uniprotkb:Cell surface receptor NYD-SP8(gene name synonym)|uniprotkb:SGRG(gene name synonym)|uniprotkb:Scleroderma-associated autoantigen(gene name synonym)|uniprotkb:Spermatogenesis-related gene protein(gene name synonym)|uniprotkb:UNQ867/PRO1884(orf name) psi-mi:ccar2_human(display_long)|uniprotkb:CCAR2(gene name)|psi-mi:CCAR2(display_short)|uniprotkb:Cell division cycle and apoptosis regulator protein 2(gene name synonym)|uniprotkb:DBC1(gene name synonym)|uniprotkb:DBIRD complex subunit KIAA1967(gene name synonym)|uniprotkb:Deleted in breast cancer gene 1 protein(gene name synonym)|uniprotkb:KIAA1967(gene name synonym)|uniprotkb:p30 DBC(gene name synonym)|uniprotkb:NET35(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Schiza et al. (2018) imex:IM-28077|pubmed:30097533 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-25504841|imex:IM-28077-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000131126(gene)|ensembl:ENST00000598265(transcript)|go:"GO:0001669"(acrosomal vesicle)|go:"GO:0002080"(acrosomal membrane)|go:"GO:0005576"(extracellular region)|go:"GO:0005886"(plasma membrane)|go:"GO:0007339"(binding of sperm to zona pellucida)|go:"GO:0009566"(fertilization)|go:"GO:0030317"(flagellated sperm motility)|go:"GO:0044853"(plasma membrane raft)|go:"GO:0046658"(anchored component of plasma membrane)|go:"GO:1901317"(regulation of flagellated sperm motility)|interpro:IPR016054(Ly-6 antigen / uPA receptor -like)|rcsb pdb:7BPR|reactome:R-HSA-163125|refseq:NP_001123483.1|refseq:NP_113639.4 refseq:NP_066997.3|ensembl:ENSG00000158941(gene)|ensembl:ENST00000308511(transcript)|ensembl:ENST00000389279(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000993"(RNA polymerase II complex binding)|go:"GO:0003723"(RNA binding)|go:"GO:0004857"(enzyme inhibitor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0005819"(spindle)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006397"(mRNA processing)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0007049"(cell cycle)|go:"GO:0008380"(RNA splicing)|go:"GO:0009411"(response to UV)|go:"GO:0016055"(Wnt signaling pathway)|interpro:IPR028811|mint:Q8N163|reactome:R-HSA-3371453|go:"GO:0019899"(enzyme binding)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0030374"(nuclear receptor coactivator activity)|go:"GO:0031647"(regulation of protein stability)|go:"GO:0032435"(negative regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0032784"(regulation of DNA-templated transcription, elongation)|go:"GO:0042752"(regulation of circadian rhythm)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043086"(negative regulation of catalytic activity)|go:"GO:0043653"(mitochondrial fragmentation involved in apoptotic process)|go:"GO:0044609"(DBIRD complex)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0048511"(rhythmic process)|go:"GO:0090263"(positive regulation of canonical Wnt signaling pathway)|go:"GO:0090311"(regulation of protein deacetylation)|go:"GO:1902230"(negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage)|go:"GO:2000003"(positive regulation of DNA damage checkpoint)|interpro:IPR011992(EF-Hand type)|interpro:IPR025223|interpro:IPR025224|interpro:IPR025954|dip:DIP-38122N - - - figure legend:Supp Table S4 and Supp Fig. S3|comment:"Coimmunoprecipitation with 34ED229 (T2) anti-TEX101 antibody"|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-testis)|taxid:9606(Homo sapiens) - 2020/03/24 2020/06/18 rogid:ZE4tXTFi7lUCcIbCL4KHzY3a6xM9606 rogid:GL+fD8W0kadrYrBkuMqoKgbbITU9606 rigid:2wTqH12DHkSLcixvnxiJPZhqAc0 false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9BY14 uniprotkb:P15880 intact:EBI-12549378|ensembl:ENSP00000472769|uniprotkb:Q7L5R2|uniprotkb:Q9BPY7 intact:EBI-443446|ensembl:ENSP00000341885|uniprotkb:Q3MIB1|uniprotkb:B2R5G0|uniprotkb:D3DU82 psi-mi:tx101_human(display_long)|uniprotkb:TEX101(gene name)|psi-mi:TEX101(display_short)|uniprotkb:Cell surface receptor NYD-SP8(gene name synonym)|uniprotkb:SGRG(gene name synonym)|uniprotkb:Scleroderma-associated autoantigen(gene name synonym)|uniprotkb:Spermatogenesis-related gene protein(gene name synonym)|uniprotkb:UNQ867/PRO1884(orf name) psi-mi:rs2_human(display_long)|uniprotkb:RPS2(gene name)|psi-mi:RPS2(display_short)|uniprotkb:RPS4(gene name synonym)|uniprotkb:40S ribosomal protein S4(gene name synonym)|uniprotkb:Protein LLRep3(gene name synonym)|uniprotkb:Small ribosomal subunit protein uS5(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Schiza et al. (2018) imex:IM-28077|pubmed:30097533 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-25504841|imex:IM-28077-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000131126(gene)|ensembl:ENST00000598265(transcript)|go:"GO:0001669"(acrosomal vesicle)|go:"GO:0002080"(acrosomal membrane)|go:"GO:0005576"(extracellular region)|go:"GO:0005886"(plasma membrane)|go:"GO:0007339"(binding of sperm to zona pellucida)|go:"GO:0009566"(fertilization)|go:"GO:0030317"(flagellated sperm motility)|go:"GO:0044853"(plasma membrane raft)|go:"GO:0046658"(anchored component of plasma membrane)|go:"GO:1901317"(regulation of flagellated sperm motility)|interpro:IPR016054(Ly-6 antigen / uPA receptor -like)|rcsb pdb:7BPR|reactome:R-HSA-163125|refseq:NP_001123483.1|refseq:NP_113639.4 interpro:IPR014721(Ribosomal protein S5 domain 2-type fold)|rcsb pdb:6OLG|rcsb pdb:6OLI|interpro:IPR018192|rcsb pdb:6OLZ|interpro:IPR020568|mint:P15880|rcsb pdb:4UG0|rcsb pdb:6OM0|rcsb pdb:4V6X|rcsb pdb:5A2Q|rcsb pdb:5AJ0|rcsb pdb:5FLX|rcsb pdb:5LKS|rcsb pdb:5OA3|rcsb pdb:5T2C|rcsb pdb:5VYC|rcsb pdb:6OM7|rcsb pdb:6QZP|rcsb pdb:6EK0|rcsb pdb:6G18|rcsb pdb:6XA1|rcsb pdb:6G4S|rcsb pdb:6G51|rcsb pdb:6G53|rcsb pdb:6Y0G|rcsb pdb:6Y2L|rcsb pdb:6G5H|rcsb pdb:6Y57|rcsb pdb:6YBD|rcsb pdb:6YBW|rcsb pdb:6Z6L|rcsb pdb:6G5I|rcsb pdb:6IP5|rcsb pdb:6Z6M|rcsb pdb:6Z6N|rcsb pdb:6ZLW|rcsb pdb:6ZM7|rcsb pdb:6ZME|rcsb pdb:6ZMI|rcsb pdb:6ZMO|rcsb pdb:6ZMT|rcsb pdb:6ZMW|rcsb pdb:6ZN5|rcsb pdb:6ZOJ|rcsb pdb:6ZOK|rcsb pdb:6ZON|rcsb pdb:6ZP4|rcsb pdb:6ZUO|rcsb pdb:6ZV6|rcsb pdb:6ZVH|rcsb pdb:6IP6|rcsb pdb:6IP8|rcsb pdb:6OLE|rcsb pdb:6OLF|rcsb pdb:6ZVJ|rcsb pdb:6ZXD|rcsb pdb:6ZXE|rcsb pdb:6ZXF|rcsb pdb:6ZXG|rcsb pdb:6ZXH|rcsb pdb:7JQB|rcsb pdb:7JQC|rcsb pdb:7K5I|reactome:R-HSA-156827|reactome:R-HSA-156902|reactome:R-HSA-1799339|reactome:R-HSA-192823|reactome:R-HSA-2408557|reactome:R-HSA-3214858|reactome:R-HSA-6790901|reactome:R-HSA-6791226|reactome:R-HSA-72649|reactome:R-HSA-72689|reactome:R-HSA-72695|reactome:R-HSA-72702|reactome:R-HSA-72706|reactome:R-HSA-72764|reactome:R-HSA-8876725|reactome:R-HSA-9010553|reactome:R-HSA-9633012|reactome:R-HSA-975956|reactome:R-HSA-975957|rcsb pdb:7A09|ensembl:ENSG00000140988(gene)|ensembl:ENST00000343262(transcript)|go:"GO:0002181"(cytoplasmic translation)|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005925"(focal adhesion)|go:"GO:0006412"(translation)|go:"GO:0016020"(membrane)|go:"GO:0017134"(fibroblast growth factor binding)|go:"GO:0019899"(enzyme binding)|go:"GO:0022626"(cytosolic ribosome)|go:"GO:0022627"(cytosolic small ribosomal subunit)|go:"GO:0045296"(cadherin binding)|go:"GO:0051443"(positive regulation of ubiquitin-protein transferase activity)|go:"GO:0070062"(extracellular exosome)|interpro:IPR000851(Ribosomal protein S5)|interpro:IPR005324(Ribosomal protein S5, C-terminal)|interpro:IPR005711(Ribosomal protein S5, eukaryotic/archaeal)|interpro:IPR013810(Ribosomal protein S5, N-terminal)|refseq:NP_002943.2 - - - figure legend:Supp Table S4 and Supp Fig. S3|comment:"Coimmunoprecipitation with 34ED229 (T2) anti-TEX101 antibody"|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-testis)|taxid:9606(Homo sapiens) - 2020/03/24 2020/06/18 rogid:ZE4tXTFi7lUCcIbCL4KHzY3a6xM9606 rogid:JUr2Y3cGk00S8KaTVPymshfaHhc9606 rigid:2wTqH12DHkSLcixvnxiJPZhqAc0 false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9BY14 uniprotkb:P55769 intact:EBI-12549378|ensembl:ENSP00000472769|uniprotkb:Q7L5R2|uniprotkb:Q9BPY7 intact:EBI-712228|ensembl:ENSP00000215956|ensembl:ENSP00000383949|ensembl:ENSP00000497142 psi-mi:tx101_human(display_long)|uniprotkb:TEX101(gene name)|psi-mi:TEX101(display_short)|uniprotkb:Cell surface receptor NYD-SP8(gene name synonym)|uniprotkb:SGRG(gene name synonym)|uniprotkb:Scleroderma-associated autoantigen(gene name synonym)|uniprotkb:Spermatogenesis-related gene protein(gene name synonym)|uniprotkb:UNQ867/PRO1884(orf name) psi-mi:nh2l1_human(display_long)|uniprotkb:SNU13(gene name)|psi-mi:SNU13(display_short)|uniprotkb:High mobility group-like nuclear protein 2 homolog 1(gene name synonym)|uniprotkb:NHP2L1(gene name synonym)|uniprotkb:OTK27(gene name synonym)|uniprotkb:SNU13 homolog(gene name synonym)|uniprotkb:U4/U6.U5 small nuclear ribonucleoprotein SNU13(gene name synonym)|uniprotkb:U4/U6.U5 tri-snRNP 15.5 kDa protein(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Schiza et al. (2018) imex:IM-28077|pubmed:30097533 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-25504841|imex:IM-28077-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000131126(gene)|ensembl:ENST00000598265(transcript)|go:"GO:0001669"(acrosomal vesicle)|go:"GO:0002080"(acrosomal membrane)|go:"GO:0005576"(extracellular region)|go:"GO:0005886"(plasma membrane)|go:"GO:0007339"(binding of sperm to zona pellucida)|go:"GO:0009566"(fertilization)|go:"GO:0030317"(flagellated sperm motility)|go:"GO:0044853"(plasma membrane raft)|go:"GO:0046658"(anchored component of plasma membrane)|go:"GO:1901317"(regulation of flagellated sperm motility)|interpro:IPR016054(Ly-6 antigen / uPA receptor -like)|rcsb pdb:7BPR|reactome:R-HSA-163125|refseq:NP_001123483.1|refseq:NP_113639.4 ensembl:ENSG00000100138(gene)|ensembl:ENST00000215956(transcript)|ensembl:ENST00000401959(transcript)|ensembl:ENST00000648674(transcript)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0000470"(maturation of LSU-rRNA)|go:"GO:0000492"(box C/D snoRNP assembly)|go:"GO:0001651"(dense fibrillar component)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005690"(U4atac snRNP)|go:"GO:0005730"(nucleolus)|go:"GO:0007338"(single fertilization)|go:"GO:0030490"(maturation of SSU-rRNA)|go:"GO:0030621"(U4 snRNA binding)|go:"GO:0030622"(U4atac snRNA binding)|go:"GO:0031428"(box C/D RNP complex)|go:"GO:0032040"(small-subunit processome)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034511"(U3 snoRNA binding)|go:"GO:0034512"(box C/D RNA binding)|go:"GO:0046540"(U4/U6 x U5 tri-snRNP complex)|go:"GO:0051117"(ATPase binding)|go:"GO:0071005"(U2-type precatalytic spliceosome)|go:"GO:0071011"(precatalytic spliceosome)|interpro:IPR002415(High mobility group-like nuclear protein)|interpro:IPR004037(Ribosomal protein L7Ae)|interpro:IPR004038(Ribosomal protein L7Ae/L30e/S12e/Gadd45)|interpro:IPR018492|interpro:IPR029064|mint:P55769|rcsb pdb:1E7K|rcsb pdb:2JNB|rcsb pdb:2OZB|rcsb pdb:3JCR|rcsb pdb:3SIU|rcsb pdb:3SIV|rcsb pdb:5O9Z|rcsb pdb:6AH0|rcsb pdb:6AHD|rcsb pdb:6QW6|rcsb pdb:6QX9|reactome:R-HSA-6790901|reactome:R-HSA-6791226|reactome:R-HSA-72163|reactome:R-HSA-72165|refseq:NP_001003796.1|refseq:NP_004999.1 - - - figure legend:Supp Table S4 and Supp Fig. S3|comment:"Coimmunoprecipitation with 34ED229 (T2) anti-TEX101 antibody"|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-testis)|taxid:9606(Homo sapiens) - 2020/03/24 2020/06/18 rogid:ZE4tXTFi7lUCcIbCL4KHzY3a6xM9606 rogid:ZMkqsDfMCrTlT/kJxillOA8839E9606 rigid:2wTqH12DHkSLcixvnxiJPZhqAc0 false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9BY14 uniprotkb:P30153 intact:EBI-12549378|ensembl:ENSP00000472769|uniprotkb:Q7L5R2|uniprotkb:Q9BPY7 intact:EBI-302388|uniprotkb:Q13773|uniprotkb:Q6ICQ3|uniprotkb:Q96DH3|ensembl:ENSP00000324804 psi-mi:tx101_human(display_long)|uniprotkb:TEX101(gene name)|psi-mi:TEX101(display_short)|uniprotkb:Cell surface receptor NYD-SP8(gene name synonym)|uniprotkb:SGRG(gene name synonym)|uniprotkb:Scleroderma-associated autoantigen(gene name synonym)|uniprotkb:Spermatogenesis-related gene protein(gene name synonym)|uniprotkb:UNQ867/PRO1884(orf name) psi-mi:2aaa_human(display_long)|uniprotkb:PPP2R1A(gene name)|psi-mi:PPP2R1A(display_short)|uniprotkb:PP2A subunit A isoform PR65-alpha(gene name synonym)|uniprotkb:PP2A subunit A isoform R1-alpha(gene name synonym)|uniprotkb:Medium tumor antigen-associated 61 kDa protein(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Schiza et al. (2018) imex:IM-28077|pubmed:30097533 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-25504841|imex:IM-28077-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000131126(gene)|ensembl:ENST00000598265(transcript)|go:"GO:0001669"(acrosomal vesicle)|go:"GO:0002080"(acrosomal membrane)|go:"GO:0005576"(extracellular region)|go:"GO:0005886"(plasma membrane)|go:"GO:0007339"(binding of sperm to zona pellucida)|go:"GO:0009566"(fertilization)|go:"GO:0030317"(flagellated sperm motility)|go:"GO:0044853"(plasma membrane raft)|go:"GO:0046658"(anchored component of plasma membrane)|go:"GO:1901317"(regulation of flagellated sperm motility)|interpro:IPR016054(Ly-6 antigen / uPA receptor -like)|rcsb pdb:7BPR|reactome:R-HSA-163125|refseq:NP_001123483.1|refseq:NP_113639.4 ensembl:ENSG00000105568(gene)|ensembl:ENST00000322088(transcript)|go:"GO:0000159"(protein phosphatase type 2A complex)|go:"GO:0000188"(obsolete inactivation of MAPK activity)|go:"GO:0000775"(chromosome, centromeric region)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0006275"(regulation of DNA replication)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006470"(protein dephosphorylation)|go:"GO:0006672"(ceramide metabolic process)|go:"GO:0006915"(apoptotic process)|go:"GO:0007059"(chromosome segregation)|go:"GO:0008380"(RNA splicing)|go:"GO:0010033"(response to organic substance)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0016020"(membrane)|go:"GO:0016328"(lateral plasma membrane)|go:"GO:0019888"(protein phosphatase regulator activity)|go:"GO:0019932"(second-messenger-mediated signaling)|go:"GO:0030111"(regulation of Wnt signaling pathway)|go:"GO:0030155"(regulation of cell adhesion)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0030425"(dendrite)|go:"GO:0040008"(regulation of growth)|go:"GO:0042532"(negative regulation of tyrosine phosphorylation of STAT protein)|go:"GO:0045595"(regulation of cell differentiation)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0065003"(protein-containing complex assembly)|go:"GO:0070062"(extracellular exosome)|go:"GO:1990405"(protein antigen binding)|interpro:IPR000357(HEAT)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR021133|interpro:IPR031090|mint:P30153|rcsb pdb:1B3U|rcsb pdb:2IE3|rcsb pdb:2IE4|rcsb pdb:2NPP|rcsb pdb:2NYL|rcsb pdb:2NYM|rcsb pdb:2PKG|rcsb pdb:3C5W|rcsb pdb:3DW8|rcsb pdb:3K7V|rcsb pdb:3K7W|rcsb pdb:4I5L|rcsb pdb:4I5N|rcsb pdb:4LAC|rcsb pdb:5W0W|rcsb pdb:6IUR|rcsb pdb:6NTS|rcsb pdb:7CUN|rcsb pdb:7K36|reactome:R-HSA-113501|reactome:R-HSA-1295596|reactome:R-HSA-141444|reactome:R-HSA-163685|reactome:R-HSA-163767|reactome:R-HSA-180024|reactome:R-HSA-195253|reactome:R-HSA-196299|reactome:R-HSA-198753|reactome:R-HSA-202670|reactome:R-HSA-2465910|reactome:R-HSA-2467813|reactome:R-HSA-2500257|reactome:R-HSA-2565942|reactome:R-HSA-2995383|reactome:R-HSA-380259|reactome:R-HSA-380270|reactome:R-HSA-380284|reactome:R-HSA-380320|reactome:R-HSA-389513|reactome:R-HSA-432142|reactome:R-HSA-4641262|reactome:R-HSA-5339716|reactome:R-HSA-5358747|reactome:R-HSA-5358749|reactome:R-HSA-5358751|reactome:R-HSA-5358752|reactome:R-HSA-5467337|reactome:R-HSA-5467340|reactome:R-HSA-5467348|reactome:R-HSA-5620912|reactome:R-HSA-5663220|reactome:R-HSA-5673000|reactome:R-HSA-5675221|reactome:R-HSA-6804757|reactome:R-HSA-6811558|reactome:R-HSA-68877|reactome:R-HSA-69231|reactome:R-HSA-69273|reactome:R-HSA-8854518|reactome:R-HSA-9634600|reactome:R-HSA-9648025|reactome:R-HSA-975957|refseq:NP_055040.2|dip:DIP-29394N - - - figure legend:Supp Table S4 and Supp Fig. S3|comment:"Coimmunoprecipitation with 34ED229 (T2) anti-TEX101 antibody"|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-testis)|taxid:9606(Homo sapiens) - 2020/03/24 2020/06/18 rogid:ZE4tXTFi7lUCcIbCL4KHzY3a6xM9606 rogid:73tR8yYYvViK8JdgIg18XWc3HRc9606 rigid:2wTqH12DHkSLcixvnxiJPZhqAc0 false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9BY14 uniprotkb:P55060 intact:EBI-12549378|ensembl:ENSP00000472769|uniprotkb:Q7L5R2|uniprotkb:Q9BPY7 intact:EBI-286709|uniprotkb:O75432|uniprotkb:Q32M40|uniprotkb:Q9H5B7|uniprotkb:Q9NTS0|uniprotkb:Q9UP98|uniprotkb:Q9UP99|uniprotkb:Q9UPA0|uniprotkb:B2R5T4|uniprotkb:E1P5Y0|uniprotkb:A3RLL6|uniprotkb:F8W904|ensembl:ENSP00000262982 psi-mi:tx101_human(display_long)|uniprotkb:TEX101(gene name)|psi-mi:TEX101(display_short)|uniprotkb:Cell surface receptor NYD-SP8(gene name synonym)|uniprotkb:SGRG(gene name synonym)|uniprotkb:Scleroderma-associated autoantigen(gene name synonym)|uniprotkb:Spermatogenesis-related gene protein(gene name synonym)|uniprotkb:UNQ867/PRO1884(orf name) psi-mi:xpo2_human(display_long)|uniprotkb:Importin-alpha re-exporter(gene name synonym)|uniprotkb:Chromosome segregation 1-like protein(gene name synonym)|uniprotkb:Cellular apoptosis susceptibility protein(gene name synonym)|uniprotkb:CSE1L(gene name)|psi-mi:CSE1L(display_short)|uniprotkb:CAS(gene name synonym)|uniprotkb:XPO2(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Schiza et al. (2018) imex:IM-28077|pubmed:30097533 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-25504841|imex:IM-28077-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000131126(gene)|ensembl:ENST00000598265(transcript)|go:"GO:0001669"(acrosomal vesicle)|go:"GO:0002080"(acrosomal membrane)|go:"GO:0005576"(extracellular region)|go:"GO:0005886"(plasma membrane)|go:"GO:0007339"(binding of sperm to zona pellucida)|go:"GO:0009566"(fertilization)|go:"GO:0030317"(flagellated sperm motility)|go:"GO:0044853"(plasma membrane raft)|go:"GO:0046658"(anchored component of plasma membrane)|go:"GO:1901317"(regulation of flagellated sperm motility)|interpro:IPR016054(Ly-6 antigen / uPA receptor -like)|rcsb pdb:7BPR|reactome:R-HSA-163125|refseq:NP_001123483.1|refseq:NP_113639.4 refseq:XP_011526901.1|refseq:NP_001307.2|refseq:NP_001243064.1|dip:DIP-32573N|ensembl:ENSG00000124207(gene)|ensembl:ENST00000262982(transcript)|go:"GO:0005049"(nuclear export signal receptor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0006611"(protein export from nucleus)|go:"GO:0016020"(membrane)|go:"GO:0031267"(small GTPase binding)|go:"GO:0070062"(extracellular exosome)|interpro:IPR001494(Importin-beta, N-terminal)|interpro:IPR005043(CAS/CSE, C-terminal)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR013713(Exportin, Cse1-like)|interpro:IPR016024(Armadillo-type fold)|mint:P55060 - - - figure legend:Supp Table S4 and Supp Fig. S3|comment:"Coimmunoprecipitation with 34ED229 (T2) anti-TEX101 antibody"|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-testis)|taxid:9606(Homo sapiens) - 2020/03/24 2020/06/18 rogid:ZE4tXTFi7lUCcIbCL4KHzY3a6xM9606 rogid:5MlTHLE2eN8Cj5K4xhSt6lCheVs9606 rigid:2wTqH12DHkSLcixvnxiJPZhqAc0 false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9BY14 uniprotkb:O75369 intact:EBI-12549378|ensembl:ENSP00000472769|uniprotkb:Q7L5R2|uniprotkb:Q9BPY7 intact:EBI-352089|intact:EBI-1754974|uniprotkb:Q13706|uniprotkb:Q59EC2|uniprotkb:Q6MZJ1|uniprotkb:Q8WXS9|uniprotkb:Q8WXT0|uniprotkb:Q8WXT1|uniprotkb:Q8WXT2|uniprotkb:Q9NRB5|uniprotkb:B2ZZ84|uniprotkb:Q9NT26|uniprotkb:Q9UEV9|intact:EBI-1960054|uniprotkb:C9JKE6|uniprotkb:B2ZZ85|uniprotkb:C9JMC4|ensembl:ENSP00000295956|uniprotkb:B2ZZ83|uniprotkb:Q60FE7|uniprotkb:Q8WXT3 psi-mi:tx101_human(display_long)|uniprotkb:TEX101(gene name)|psi-mi:TEX101(display_short)|uniprotkb:Cell surface receptor NYD-SP8(gene name synonym)|uniprotkb:SGRG(gene name synonym)|uniprotkb:Scleroderma-associated autoantigen(gene name synonym)|uniprotkb:Spermatogenesis-related gene protein(gene name synonym)|uniprotkb:UNQ867/PRO1884(orf name) psi-mi:flnb_human(display_long)|uniprotkb:FLNB(gene name)|psi-mi:FLNB(display_short)|uniprotkb:FLN1L(gene name synonym)|uniprotkb:FLN3(gene name synonym)|uniprotkb:TABP(gene name synonym)|uniprotkb:TAP(gene name synonym)|uniprotkb:Beta-filamin(gene name synonym)|uniprotkb:Actin-binding-like protein(gene name synonym)|uniprotkb:Thyroid autoantigen(gene name synonym)|uniprotkb:Truncated actin-binding protein(gene name synonym)|uniprotkb:ABP-280 homolog(gene name synonym)|uniprotkb:ABP-278(gene name synonym)|uniprotkb:Filamin-3(gene name synonym)|uniprotkb:Filamin homolog 1(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Schiza et al. (2018) imex:IM-28077|pubmed:30097533 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-25504841|imex:IM-28077-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000131126(gene)|ensembl:ENST00000598265(transcript)|go:"GO:0001669"(acrosomal vesicle)|go:"GO:0002080"(acrosomal membrane)|go:"GO:0005576"(extracellular region)|go:"GO:0005886"(plasma membrane)|go:"GO:0007339"(binding of sperm to zona pellucida)|go:"GO:0009566"(fertilization)|go:"GO:0030317"(flagellated sperm motility)|go:"GO:0044853"(plasma membrane raft)|go:"GO:0046658"(anchored component of plasma membrane)|go:"GO:1901317"(regulation of flagellated sperm motility)|interpro:IPR016054(Ly-6 antigen / uPA receptor -like)|rcsb pdb:7BPR|reactome:R-HSA-163125|refseq:NP_001123483.1|refseq:NP_113639.4 refseq:NP_001157791.1|refseq:NP_001448.2|go:"GO:0003334"(keratinocyte development)|go:"GO:0003382"(epithelial cell morphogenesis)|go:"GO:0003723"(RNA binding)|go:"GO:0003779"(actin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005903"(brush border)|go:"GO:0005925"(focal adhesion)|go:"GO:0005938"(cell cortex)|go:"GO:0007165"(signal transduction)|go:"GO:0007519"(skeletal muscle tissue development)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030018"(Z disc)|go:"GO:0030036"(actin cytoskeleton organization)|go:"GO:0042802"(identical protein binding)|go:"GO:0043005"(neuron projection)|go:"GO:0043025"(neuronal cell body)|go:"GO:0045296"(cadherin binding)|go:"GO:0045335"(phagocytic vesicle)|go:"GO:0051015"(actin filament binding)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071346"(cellular response to interferon-gamma)|interpro:IPR001298(Filamin/ABP280 repeat)|interpro:IPR001589(Actinin-type, actin-binding, conserved site)|interpro:IPR001715(Calponin-like actin-binding)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR014756(Immunoglobulin E-set)|interpro:IPR017868|interpro:IPR029874|interpro:IPR036872|interpro:IPR044801|mint:O75369|rcsb pdb:2DI8|rcsb pdb:2DI9|rcsb pdb:2DIA|rcsb pdb:2DIB|rcsb pdb:2DIC|rcsb pdb:2DJ4|rcsb pdb:2DLG|rcsb pdb:2DMB|rcsb pdb:2DMC|rcsb pdb:2E9I|rcsb pdb:2E9J|rcsb pdb:2EE6|rcsb pdb:2EE9|rcsb pdb:2EEA|rcsb pdb:2EEB|rcsb pdb:2EEC|rcsb pdb:2EED|rcsb pdb:2WA5|rcsb pdb:2WA6|rcsb pdb:2WA7|rcsb pdb:3FER|rcsb pdb:4B7L|rcsb pdb:5DCP|reactome:R-HSA-1169408|ensembl:ENSG00000136068(gene)|ensembl:ENST00000295956(transcript)|go:"GO:0001725"(stress fiber)|refseq:NP_001157789.1|refseq:NP_001157790.1 - - - figure legend:Supp Table S4 and Supp Fig. S3|comment:"Coimmunoprecipitation with 34ED229 (T2) anti-TEX101 antibody"|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-testis)|taxid:9606(Homo sapiens) - 2020/03/24 2020/06/18 rogid:ZE4tXTFi7lUCcIbCL4KHzY3a6xM9606 rogid:lsf6C/Vg0io7UhUi1Kapgwp0p5E9606 rigid:2wTqH12DHkSLcixvnxiJPZhqAc0 false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9BY14 uniprotkb:O60664 intact:EBI-12549378|ensembl:ENSP00000472769|uniprotkb:Q7L5R2|uniprotkb:Q9BPY7 intact:EBI-725795|uniprotkb:Q53G77|uniprotkb:Q9BS03|uniprotkb:Q9UBD7|uniprotkb:Q9UP92|uniprotkb:A8K4Y9|intact:EBI-11103673|uniprotkb:K7EQF4|ensembl:ENSP00000221957 psi-mi:tx101_human(display_long)|uniprotkb:TEX101(gene name)|psi-mi:TEX101(display_short)|uniprotkb:Cell surface receptor NYD-SP8(gene name synonym)|uniprotkb:SGRG(gene name synonym)|uniprotkb:Scleroderma-associated autoantigen(gene name synonym)|uniprotkb:Spermatogenesis-related gene protein(gene name synonym)|uniprotkb:UNQ867/PRO1884(orf name) psi-mi:plin3_human(display_long)|uniprotkb:Cargo selection protein TIP47(gene name synonym)|uniprotkb:47 kDa mannose 6-phosphate receptor-binding protein(gene name synonym)|uniprotkb:Placental protein 17(gene name synonym)|uniprotkb:PLIN3(gene name)|psi-mi:PLIN3(display_short)|uniprotkb:TIP47(gene name synonym)|uniprotkb:M6PRBP1(gene name synonym)|uniprotkb:Mannose-6-phosphate receptor-binding protein 1(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Schiza et al. (2018) imex:IM-28077|pubmed:30097533 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-25504841|imex:IM-28077-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000131126(gene)|ensembl:ENST00000598265(transcript)|go:"GO:0001669"(acrosomal vesicle)|go:"GO:0002080"(acrosomal membrane)|go:"GO:0005576"(extracellular region)|go:"GO:0005886"(plasma membrane)|go:"GO:0007339"(binding of sperm to zona pellucida)|go:"GO:0009566"(fertilization)|go:"GO:0030317"(flagellated sperm motility)|go:"GO:0044853"(plasma membrane raft)|go:"GO:0046658"(anchored component of plasma membrane)|go:"GO:1901317"(regulation of flagellated sperm motility)|interpro:IPR016054(Ly-6 antigen / uPA receptor -like)|rcsb pdb:7BPR|reactome:R-HSA-163125|refseq:NP_001123483.1|refseq:NP_113639.4 refseq:NP_001157666.1|refseq:NP_001157661.1|refseq:NP_005808.3|go:"GO:0016020"(membrane)|go:"GO:0016192"(vesicle-mediated transport)|go:"GO:0019915"(lipid storage)|go:"GO:0030133"(transport vesicle)|ensembl:ENSG00000105355(gene)|go:"GO:0045296"(cadherin binding)|interpro:IPR004279(Perilipin)|reactome:R-HSA-163560|reactome:R-HSA-6811440|reactome:R-HSA-9613354|ensembl:ENST00000221957(transcript)|reactome:R-HSA-9613829|reactome:R-HSA-9615710|reactome:R-HSA-9706019|go:"GO:0005737"(cytoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005811"(lipid droplet)|go:"GO:0005829"(cytosol)|go:"GO:0010008"(endosome membrane)|go:"GO:0010890"(positive regulation of sequestering of triglyceride) - - - figure legend:Supp Table S4 and Supp Fig. S3|comment:"Coimmunoprecipitation with 34ED229 (T2) anti-TEX101 antibody"|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-testis)|taxid:9606(Homo sapiens) - 2020/03/24 2020/06/18 rogid:ZE4tXTFi7lUCcIbCL4KHzY3a6xM9606 rogid:U+skqZ/oQtQscaEvfdh+AVnCCKA9606 rigid:2wTqH12DHkSLcixvnxiJPZhqAc0 false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9BY14 uniprotkb:P56134 intact:EBI-12549378|ensembl:ENSP00000472769|uniprotkb:Q7L5R2|uniprotkb:Q9BPY7 intact:EBI-712794|ensembl:ENSP00000292475|uniprotkb:O76079|uniprotkb:Q96L83|uniprotkb:Q9BTI8|uniprotkb:C9J8H9|uniprotkb:F8W7V3|intact:EBI-11047094|uniprotkb:Q6IBB3 psi-mi:tx101_human(display_long)|uniprotkb:TEX101(gene name)|psi-mi:TEX101(display_short)|uniprotkb:Cell surface receptor NYD-SP8(gene name synonym)|uniprotkb:SGRG(gene name synonym)|uniprotkb:Scleroderma-associated autoantigen(gene name synonym)|uniprotkb:Spermatogenesis-related gene protein(gene name synonym)|uniprotkb:UNQ867/PRO1884(orf name) psi-mi:atpk_human(display_long)|uniprotkb:ATP5MF(gene name)|psi-mi:ATP5MF(display_short)|uniprotkb:ATP synthase membrane subunit f(gene name synonym)|uniprotkb:ATP5J2(gene name synonym)|uniprotkb:ATP5JL(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Schiza et al. (2018) imex:IM-28077|pubmed:30097533 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-25504841|imex:IM-28077-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000131126(gene)|ensembl:ENST00000598265(transcript)|go:"GO:0001669"(acrosomal vesicle)|go:"GO:0002080"(acrosomal membrane)|go:"GO:0005576"(extracellular region)|go:"GO:0005886"(plasma membrane)|go:"GO:0007339"(binding of sperm to zona pellucida)|go:"GO:0009566"(fertilization)|go:"GO:0030317"(flagellated sperm motility)|go:"GO:0044853"(plasma membrane raft)|go:"GO:0046658"(anchored component of plasma membrane)|go:"GO:1901317"(regulation of flagellated sperm motility)|interpro:IPR016054(Ly-6 antigen / uPA receptor -like)|rcsb pdb:7BPR|reactome:R-HSA-163125|refseq:NP_001123483.1|refseq:NP_113639.4 ensembl:ENSG00000241468(gene)|ensembl:ENST00000292475(transcript)|go:"GO:0000276"("mitochondrial proton-transporting ATP synthase complex, coupling factor F(o)")|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005753"(mitochondrial proton-transporting ATP synthase complex)|go:"GO:0016021"(integral component of membrane)|go:"GO:0031965"(nuclear membrane)|go:"GO:0042776"(mitochondrial ATP synthesis coupled proton transport)|go:"GO:1902600"(proton transmembrane transport)|interpro:IPR019344|mint:P56134|reactome:R-HSA-163210|reactome:R-HSA-8949613|refseq:NP_001003713.1|refseq:NP_004880.1|refseq:NP_001003714.1|refseq:NP_001034267.1 - - - figure legend:Supp Table S4 and Supp Fig. S3|comment:"Coimmunoprecipitation with 34ED229 (T2) anti-TEX101 antibody"|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-testis)|taxid:9606(Homo sapiens) - 2020/03/24 2020/06/18 rogid:ZE4tXTFi7lUCcIbCL4KHzY3a6xM9606 rogid:+WS7rjFef6JE+mlZ4Q8TF2A+G0E9606 rigid:2wTqH12DHkSLcixvnxiJPZhqAc0 false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9BY14 uniprotkb:O14756 intact:EBI-12549378|ensembl:ENSP00000472769|uniprotkb:Q7L5R2|uniprotkb:Q9BPY7 intact:EBI-21599052|uniprotkb:O43275|ensembl:ENSP00000318631|ensembl:ENSP00000450698|ensembl:ENSP00000451406|ensembl:ENSP00000451753|ensembl:ENSP00000452273 psi-mi:tx101_human(display_long)|uniprotkb:TEX101(gene name)|psi-mi:TEX101(display_short)|uniprotkb:Cell surface receptor NYD-SP8(gene name synonym)|uniprotkb:SGRG(gene name synonym)|uniprotkb:Scleroderma-associated autoantigen(gene name synonym)|uniprotkb:Spermatogenesis-related gene protein(gene name synonym)|uniprotkb:UNQ867/PRO1884(orf name) psi-mi:h17b6_human(display_long)|uniprotkb:3-alpha->beta-hydroxysteroid epimerase(gene name synonym)|uniprotkb:Oxidative 3-alpha hydroxysteroid dehydrogenase(gene name synonym)|uniprotkb:Short chain dehydrogenase/reductase family 9C member 6(gene name synonym)|uniprotkb:HSD17B6(gene name)|psi-mi:HSD17B6(display_short)|uniprotkb:RODH(gene name synonym)|uniprotkb:SDR9C6(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Schiza et al. (2018) imex:IM-28077|pubmed:30097533 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-25504841|imex:IM-28077-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000131126(gene)|ensembl:ENST00000598265(transcript)|go:"GO:0001669"(acrosomal vesicle)|go:"GO:0002080"(acrosomal membrane)|go:"GO:0005576"(extracellular region)|go:"GO:0005886"(plasma membrane)|go:"GO:0007339"(binding of sperm to zona pellucida)|go:"GO:0009566"(fertilization)|go:"GO:0030317"(flagellated sperm motility)|go:"GO:0044853"(plasma membrane raft)|go:"GO:0046658"(anchored component of plasma membrane)|go:"GO:1901317"(regulation of flagellated sperm motility)|interpro:IPR016054(Ly-6 antigen / uPA receptor -like)|rcsb pdb:7BPR|reactome:R-HSA-163125|refseq:NP_001123483.1|refseq:NP_113639.4 refseq:NP_003716.2|refseq:XP_005269264.1|refseq:XP_005269265.1|refseq:XP_005269266.1|refseq:XP_006719735.1|refseq:XP_011537227.1|refseq:XP_011537228.1|refseq:XP_011537229.1|ensembl:ENSG00000025423(gene)|ensembl:ENST00000322165(transcript)|ensembl:ENST00000554150(transcript)|ensembl:ENST00000554643(transcript)|ensembl:ENST00000555159(transcript)|ensembl:ENST00000555805(transcript)|go:"GO:0003824"(catalytic activity)|go:"GO:0004745"(NAD-retinol dehydrogenase activity)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0006702"(androgen biosynthetic process)|go:"GO:0006710"(androgen catabolic process)|go:"GO:0009055"(electron transfer activity)|go:"GO:0016491"(oxidoreductase activity)|go:"GO:0031901"(early endosome membrane)|go:"GO:0044594"("17-beta-hydroxysteroid dehydrogenase (NAD+) activity")|go:"GO:0047023"(androsterone dehydrogenase activity)|go:"GO:0047024"(5alpha-androstane-3beta,17beta-diol dehydrogenase activity)|go:"GO:0047035"("testosterone dehydrogenase (NAD+) activity")|go:"GO:0047044"(androstan-3-alpha,17-beta-diol dehydrogenase activity)|go:"GO:0047045"("testosterone 17-beta-dehydrogenase (NADP+) activity")|go:"GO:0062175"(brexanolone catabolic process)|go:"GO:0072582"("17-beta-hydroxysteroid dehydrogenase (NADP+) activity")|interpro:IPR002347(Glucose/ribitol dehydrogenase)|interpro:IPR020904|interpro:IPR036291|reactome:R-HSA-2453902 - - - figure legend:Supp Table S4 and Supp Fig. S3|comment:"Coimmunoprecipitation with 34ED229 (T2) anti-TEX101 antibody"|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-testis)|taxid:9606(Homo sapiens) - 2020/03/24 2020/06/18 rogid:ZE4tXTFi7lUCcIbCL4KHzY3a6xM9606 rogid:DcOlelhxAt7zSxwwYVxqmgck3X09606 rigid:2wTqH12DHkSLcixvnxiJPZhqAc0 false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9BY14 uniprotkb:Q99878 intact:EBI-12549378|ensembl:ENSP00000472769|uniprotkb:Q7L5R2|uniprotkb:Q9BPY7 intact:EBI-6147676|uniprotkb:Q5JXQ5|uniprotkb:A2RUU6|ensembl:ENSP00000328484 psi-mi:tx101_human(display_long)|uniprotkb:TEX101(gene name)|psi-mi:TEX101(display_short)|uniprotkb:Cell surface receptor NYD-SP8(gene name synonym)|uniprotkb:SGRG(gene name synonym)|uniprotkb:Scleroderma-associated autoantigen(gene name synonym)|uniprotkb:Spermatogenesis-related gene protein(gene name synonym)|uniprotkb:UNQ867/PRO1884(orf name) psi-mi:h2a1j_human(display_long)|uniprotkb:H2AC14(gene name)|psi-mi:H2AC14(display_short)|uniprotkb:H2AFE(gene name synonym)|uniprotkb:HIST1H2AJ(gene name synonym)|uniprotkb:Histone H2A/e(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Schiza et al. (2018) imex:IM-28077|pubmed:30097533 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-25504841|imex:IM-28077-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000131126(gene)|ensembl:ENST00000598265(transcript)|go:"GO:0001669"(acrosomal vesicle)|go:"GO:0002080"(acrosomal membrane)|go:"GO:0005576"(extracellular region)|go:"GO:0005886"(plasma membrane)|go:"GO:0007339"(binding of sperm to zona pellucida)|go:"GO:0009566"(fertilization)|go:"GO:0030317"(flagellated sperm motility)|go:"GO:0044853"(plasma membrane raft)|go:"GO:0046658"(anchored component of plasma membrane)|go:"GO:1901317"(regulation of flagellated sperm motility)|interpro:IPR016054(Ly-6 antigen / uPA receptor -like)|rcsb pdb:7BPR|reactome:R-HSA-163125|refseq:NP_001123483.1|refseq:NP_113639.4 refseq:NP_066544.1|ensembl:ENSG00000276368(gene)|ensembl:ENST00000333151(transcript)|go:"GO:0000786"(nucleosome)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0006342"|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0070062"(extracellular exosome)|interpro:IPR002119(Histone H2A)|interpro:IPR007125(Histone core)|interpro:IPR009072(Histone-fold)|interpro:IPR032454|interpro:IPR032458|reactome:R-HSA-110328|reactome:R-HSA-110329|reactome:R-HSA-110330|reactome:R-HSA-110331|reactome:R-HSA-1221632|reactome:R-HSA-171306|reactome:R-HSA-1912408|reactome:R-HSA-201722|reactome:R-HSA-212300|reactome:R-HSA-2299718|reactome:R-HSA-2559580|reactome:R-HSA-2559582|reactome:R-HSA-2559586|reactome:R-HSA-3214815|reactome:R-HSA-3214847|reactome:R-HSA-3214858|reactome:R-HSA-427359|reactome:R-HSA-427389|reactome:R-HSA-427413|reactome:R-HSA-5250924|reactome:R-HSA-5334118|reactome:R-HSA-5578749|reactome:R-HSA-5617472|reactome:R-HSA-5625886|reactome:R-HSA-5689603|reactome:R-HSA-5689880|reactome:R-HSA-5689901|reactome:R-HSA-606279|reactome:R-HSA-73728|reactome:R-HSA-73772|reactome:R-HSA-8936459|reactome:R-HSA-8939236|reactome:R-HSA-9018519|reactome:R-HSA-912446|reactome:R-HSA-9609690|reactome:R-HSA-9610379|reactome:R-HSA-9616222|reactome:R-HSA-9670095|reactome:R-HSA-9710421|reactome:R-HSA-977225 - - - figure legend:Supp Table S4 and Supp Fig. S3|comment:"Coimmunoprecipitation with 34ED229 (T2) anti-TEX101 antibody"|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-testis)|taxid:9606(Homo sapiens) - 2020/03/24 2020/06/18 rogid:ZE4tXTFi7lUCcIbCL4KHzY3a6xM9606 rogid:tS29VG3PpglHaYbu0w5z7pGvYyI9606 rigid:2wTqH12DHkSLcixvnxiJPZhqAc0 false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9BY14 uniprotkb:P06727 intact:EBI-12549378|ensembl:ENSP00000472769|uniprotkb:Q7L5R2|uniprotkb:Q9BPY7 intact:EBI-1222447|uniprotkb:Q14CW8|uniprotkb:Q6Q787|uniprotkb:A8MSL6|ensembl:ENSP00000350425 psi-mi:tx101_human(display_long)|uniprotkb:TEX101(gene name)|psi-mi:TEX101(display_short)|uniprotkb:Cell surface receptor NYD-SP8(gene name synonym)|uniprotkb:SGRG(gene name synonym)|uniprotkb:Scleroderma-associated autoantigen(gene name synonym)|uniprotkb:Spermatogenesis-related gene protein(gene name synonym)|uniprotkb:UNQ867/PRO1884(orf name) psi-mi:apoa4_human(display_long)|uniprotkb:APOA4(gene name)|psi-mi:APOA4(display_short)|uniprotkb:Apolipoprotein A4(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Schiza et al. (2018) imex:IM-28077|pubmed:30097533 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-25504841|imex:IM-28077-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000131126(gene)|ensembl:ENST00000598265(transcript)|go:"GO:0001669"(acrosomal vesicle)|go:"GO:0002080"(acrosomal membrane)|go:"GO:0005576"(extracellular region)|go:"GO:0005886"(plasma membrane)|go:"GO:0007339"(binding of sperm to zona pellucida)|go:"GO:0009566"(fertilization)|go:"GO:0030317"(flagellated sperm motility)|go:"GO:0044853"(plasma membrane raft)|go:"GO:0046658"(anchored component of plasma membrane)|go:"GO:1901317"(regulation of flagellated sperm motility)|interpro:IPR016054(Ly-6 antigen / uPA receptor -like)|rcsb pdb:7BPR|reactome:R-HSA-163125|refseq:NP_001123483.1|refseq:NP_113639.4 refseq:NP_000473.2|dip:DIP-38333N|ensembl:ENSG00000110244(gene)|ensembl:ENST00000357780(transcript)|go:"GO:0002227"(innate immune response in mucosa)|go:"GO:0005319"(lipid transporter activity)|go:"GO:0005507"(copper ion binding)|go:"GO:0005543"(phospholipid binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0005769"(early endosome)|go:"GO:0005788"(endoplasmic reticulum lumen)|go:"GO:0005829"(cytosol)|go:"GO:0006695"(cholesterol biosynthetic process)|go:"GO:0006869"(lipid transport)|go:"GO:0006982"(response to lipid hydroperoxide)|go:"GO:0007159"(leukocyte cell-cell adhesion)|go:"GO:0008203"(cholesterol metabolic process)|go:"GO:0008289"(lipid binding)|go:"GO:0010873"(positive regulation of cholesterol esterification)|go:"GO:0010898"(positive regulation of triglyceride catabolic process)|go:"GO:0015485"(cholesterol binding)|go:"GO:0016042"(lipid catabolic process)|go:"GO:0016209"(antioxidant activity)|go:"GO:0019430"(removal of superoxide radicals)|go:"GO:0030300"(regulation of intestinal cholesterol absorption)|go:"GO:0031210"(phosphatidylcholine binding)|go:"GO:0032374"(regulation of cholesterol transport)|go:"GO:0033344"(cholesterol efflux)|go:"GO:0033700"(phospholipid efflux)|go:"GO:0034361"(very-low-density lipoprotein particle)|go:"GO:0034364"(high-density lipoprotein particle)|go:"GO:0034371"(chylomicron remodeling)|go:"GO:0034372"(very-low-density lipoprotein particle remodeling)|go:"GO:0034375"(high-density lipoprotein particle remodeling)|go:"GO:0034378"(chylomicron assembly)|go:"GO:0034380"(high-density lipoprotein particle assembly)|go:"GO:0034445"(negative regulation of plasma lipoprotein oxidation)|go:"GO:0035634"(response to stilbenoid)|go:"GO:0042157"(lipoprotein metabolic process)|go:"GO:0042627"(chylomicron)|go:"GO:0042632"(cholesterol homeostasis)|go:"GO:0042744"(hydrogen peroxide catabolic process)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043691"(reverse cholesterol transport)|go:"GO:0045723"(positive regulation of fatty acid biosynthetic process)|go:"GO:0046470"(phosphatidylcholine metabolic process)|go:"GO:0046889"(positive regulation of lipid biosynthetic process)|go:"GO:0051006"(positive regulation of lipoprotein lipase activity)|go:"GO:0055088"(lipid homeostasis)|go:"GO:0060228"(phosphatidylcholine-sterol O-acyltransferase activator activity)|go:"GO:0062023"(collagen-containing extracellular matrix)|go:"GO:0065005"(protein-lipid complex assembly)|go:"GO:0070062"(extracellular exosome)|go:"GO:0072562"(blood microparticle)|go:"GO:0120020"(cholesterol transfer activity)|interpro:IPR000074(Apolipoprotein A1/A4/E)|rcsb pdb:3S84|reactome:R-HSA-8963888|reactome:R-HSA-8963889|reactome:R-HSA-8963901|reactome:R-HSA-975634|reactome:R-HSA-977225|go:"GO:0070328"(triglyceride homeostasis) - - - figure legend:Supp Table S4 and Supp Fig. S3|comment:"Coimmunoprecipitation with 34ED229 (T2) anti-TEX101 antibody"|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-testis)|taxid:9606(Homo sapiens) - 2020/03/24 2020/06/18 rogid:ZE4tXTFi7lUCcIbCL4KHzY3a6xM9606 rogid:95b7Xlqg/plh9/R7xhLBsMXQscM9606 rigid:2wTqH12DHkSLcixvnxiJPZhqAc0 false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9BY14 uniprotkb:P27824 intact:EBI-12549378|ensembl:ENSP00000472769|uniprotkb:Q7L5R2|uniprotkb:Q9BPY7 intact:EBI-355947|uniprotkb:D3DWQ3|uniprotkb:B2R5V8|ensembl:ENSP00000421434|ensembl:ENSP00000421813|ensembl:ENSP00000424063|ensembl:ENSP00000424745|ensembl:ENSP00000491760|ensembl:ENSP00000492372|ensembl:ENSP00000492868|ensembl:ENSP00000505013|ensembl:ENSP00000505202|ensembl:ENSP00000505526|ensembl:ENSP00000505960|ensembl:ENSP00000506003|ensembl:ENSP00000506021|ensembl:ENSP00000506061|ensembl:ENSP00000506078|ensembl:ENSP00000506509|ensembl:ENSP00000506568|ensembl:ENSP00000506583|ensembl:ENSP00000247461|ensembl:ENSP00000391646|intact:EBI-9513217|uniprotkb:B4DGP8|uniprotkb:B4E2T8|uniprotkb:D6R9K3 psi-mi:tx101_human(display_long)|uniprotkb:TEX101(gene name)|psi-mi:TEX101(display_short)|uniprotkb:Cell surface receptor NYD-SP8(gene name synonym)|uniprotkb:SGRG(gene name synonym)|uniprotkb:Scleroderma-associated autoantigen(gene name synonym)|uniprotkb:Spermatogenesis-related gene protein(gene name synonym)|uniprotkb:UNQ867/PRO1884(orf name) psi-mi:calx_human(display_long)|uniprotkb:CANX(gene name)|psi-mi:CANX(display_short)|uniprotkb:Major histocompatibility complex class I antigen-binding protein p88(gene name synonym)|uniprotkb:p90(gene name synonym)|uniprotkb:IP90(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Schiza et al. (2018) imex:IM-28077|pubmed:30097533 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-25504841|imex:IM-28077-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000131126(gene)|ensembl:ENST00000598265(transcript)|go:"GO:0001669"(acrosomal vesicle)|go:"GO:0002080"(acrosomal membrane)|go:"GO:0005576"(extracellular region)|go:"GO:0005886"(plasma membrane)|go:"GO:0007339"(binding of sperm to zona pellucida)|go:"GO:0009566"(fertilization)|go:"GO:0030317"(flagellated sperm motility)|go:"GO:0044853"(plasma membrane raft)|go:"GO:0046658"(anchored component of plasma membrane)|go:"GO:1901317"(regulation of flagellated sperm motility)|interpro:IPR016054(Ly-6 antigen / uPA receptor -like)|rcsb pdb:7BPR|reactome:R-HSA-163125|refseq:NP_001123483.1|refseq:NP_113639.4 refseq:NP_001019820.1|refseq:NP_001737.1|refseq:XP_011532967.1|go:"GO:0099059"(integral component of presynaptic active zone membrane)|interpro:IPR001580(Calreticulin/calnexin)|interpro:IPR009033(Calreticulin/calnexin, P)|interpro:IPR013320(Concanavalin A-like lectin/glucanase, subgroup)|interpro:IPR018124|mint:P27824|reactome:R-HSA-168316|reactome:R-HSA-2132295|reactome:R-HSA-8984722|reactome:R-HSA-901042|reactome:R-HSA-9020956|reactome:R-HSA-9683686|reactome:R-HSA-9694548|reactome:R-HSA-983170|ensembl:ENST00000452673(transcript)|ensembl:ENST00000502296(transcript)|ensembl:ENST00000504734(transcript)|ensembl:ENST00000509563(transcript)|ensembl:ENST00000513246(transcript)|ensembl:ENST00000638425(transcript)|ensembl:ENST00000638706(transcript)|ensembl:ENST00000639938(transcript)|ensembl:ENST00000680013(transcript)|ensembl:ENST00000680042(transcript)|ensembl:ENST00000680092(transcript)|ensembl:ENST00000680618(transcript)|ensembl:ENST00000681072(transcript)|ensembl:ENST00000681168(transcript)|ensembl:ENST00000681476(transcript)|ensembl:ENST00000681674(transcript)|ensembl:ENST00000681712(transcript)|ensembl:ENST00000681733(transcript)|ensembl:ENST00000681903(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005788"(endoplasmic reticulum lumen)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005790"(smooth endoplasmic reticulum)|ensembl:ENST00000247461(transcript)|go:"GO:0005840"(ribosome)|go:"GO:0006457"(protein folding)|go:"GO:0007568"(aging)|go:"GO:0009306"(protein secretion)|go:"GO:0016020"(membrane)|go:"GO:0019082"(viral protein processing)|go:"GO:0030246"(carbohydrate binding)|go:"GO:0030424"(axon)|go:"GO:0030968"(endoplasmic reticulum unfolded protein response)|go:"GO:0032839"(dendrite cytoplasm)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034185"(apolipoprotein binding)|go:"GO:0034975"(protein folding in endoplasmic reticulum)|go:"GO:0035255"(ionotropic glutamate receptor binding)|go:"GO:0042470"(melanosome)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043197"(dendritic spine)|go:"GO:0044233"(mitochondria-associated endoplasmic reticulum membrane)|go:"GO:0044322"(endoplasmic reticulum quality control compartment)|go:"GO:0048488"(synaptic vesicle endocytosis)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071556"(integral component of lumenal side of endoplasmic reticulum membrane)|go:"GO:0072583"(clathrin-dependent endocytosis)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099055"(integral component of postsynaptic membrane)|go:"GO:0005791"(rough endoplasmic reticulum)|ensembl:ENSG00000127022(gene)|ensembl:ENSG00000283777(gene)|dip:DIP-457N - - - figure legend:Supp Table S4 and Supp Fig. S3|comment:"Coimmunoprecipitation with 34ED229 (T2) anti-TEX101 antibody"|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-testis)|taxid:9606(Homo sapiens) - 2020/03/24 2020/06/18 rogid:ZE4tXTFi7lUCcIbCL4KHzY3a6xM9606 rogid:Vy9HZjl19IXifyFpueW0LXi9ENk9606 rigid:2wTqH12DHkSLcixvnxiJPZhqAc0 false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9BY14 uniprotkb:P68032 intact:EBI-12549378|ensembl:ENSP00000472769|uniprotkb:Q7L5R2|uniprotkb:Q9BPY7 intact:EBI-352273|uniprotkb:P04270|ensembl:ENSP00000290378 psi-mi:tx101_human(display_long)|uniprotkb:TEX101(gene name)|psi-mi:TEX101(display_short)|uniprotkb:Cell surface receptor NYD-SP8(gene name synonym)|uniprotkb:SGRG(gene name synonym)|uniprotkb:Scleroderma-associated autoantigen(gene name synonym)|uniprotkb:Spermatogenesis-related gene protein(gene name synonym)|uniprotkb:UNQ867/PRO1884(orf name) psi-mi:actc_human(display_long)|uniprotkb:ACTC1(gene name)|psi-mi:ACTC1(display_short)|uniprotkb:ACTC(gene name synonym)|uniprotkb:Alpha-cardiac actin(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Schiza et al. (2018) imex:IM-28077|pubmed:30097533 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-25504841|imex:IM-28077-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000131126(gene)|ensembl:ENST00000598265(transcript)|go:"GO:0001669"(acrosomal vesicle)|go:"GO:0002080"(acrosomal membrane)|go:"GO:0005576"(extracellular region)|go:"GO:0005886"(plasma membrane)|go:"GO:0007339"(binding of sperm to zona pellucida)|go:"GO:0009566"(fertilization)|go:"GO:0030317"(flagellated sperm motility)|go:"GO:0044853"(plasma membrane raft)|go:"GO:0046658"(anchored component of plasma membrane)|go:"GO:1901317"(regulation of flagellated sperm motility)|interpro:IPR016054(Ly-6 antigen / uPA receptor -like)|rcsb pdb:7BPR|reactome:R-HSA-163125|refseq:NP_001123483.1|refseq:NP_113639.4 refseq:NP_005150.1|ensembl:ENSG00000159251(gene)|ensembl:ENST00000290378(transcript)|go:"GO:0000146"(microfilament motor activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005869"(dynactin complex)|go:"GO:0005884"(actin filament)|go:"GO:0005925"(focal adhesion)|go:"GO:0007015"(actin filament organization)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0016020"(membrane)|go:"GO:0017022"(myosin binding)|go:"GO:0030017"(sarcomere)|go:"GO:0030027"(lamellipodium)|go:"GO:0030048"(actin filament-based movement)|go:"GO:0030175"(filopodium)|go:"GO:0030240"(skeletal muscle thin filament assembly)|go:"GO:0031032"(actomyosin structure organization)|go:"GO:0031674"(I band)|go:"GO:0033275"(actin-myosin filament sliding)|go:"GO:0042493"|go:"GO:0044297"(cell body)|go:"GO:0045471"(response to ethanol)|go:"GO:0055003"(cardiac myofibril assembly)|go:"GO:0055008"(cardiac muscle tissue morphogenesis)|go:"GO:0060047"(heart contraction)|go:"GO:0060048"(cardiac muscle contraction)|go:"GO:0070062"(extracellular exosome)|go:"GO:0072562"(blood microparticle)|go:"GO:0090131"(mesenchyme migration)|interpro:IPR004000(Actin/actin-like)|interpro:IPR004001(Actin, conserved site)|interpro:IPR020902|interpro:IPR043129|mint:P68032|reactome:R-HSA-390522|reactome:R-HSA-8980692|reactome:R-HSA-9013026 - - - figure legend:Supp Table S4 and Supp Fig. S3|comment:"Coimmunoprecipitation with 34ED229 (T2) anti-TEX101 antibody"|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-testis)|taxid:9606(Homo sapiens) - 2020/03/24 2020/06/18 rogid:ZE4tXTFi7lUCcIbCL4KHzY3a6xM9606 rogid:U/lKYqWUWMSC3fBHFaAcgzfk+3w9606 rigid:2wTqH12DHkSLcixvnxiJPZhqAc0 false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9BY14 uniprotkb:Q9H1E5 intact:EBI-12549378|ensembl:ENSP00000472769|uniprotkb:Q7L5R2|uniprotkb:Q9BPY7 intact:EBI-2685885|uniprotkb:Q8N4P7|uniprotkb:Q9ULQ8|uniprotkb:Q8NCC1|uniprotkb:Q9UJA1|ensembl:ENSP00000246024 psi-mi:tx101_human(display_long)|uniprotkb:TEX101(gene name)|psi-mi:TEX101(display_short)|uniprotkb:Cell surface receptor NYD-SP8(gene name synonym)|uniprotkb:SGRG(gene name synonym)|uniprotkb:Scleroderma-associated autoantigen(gene name synonym)|uniprotkb:Spermatogenesis-related gene protein(gene name synonym)|uniprotkb:UNQ867/PRO1884(orf name) psi-mi:tmx4_human(display_long)|uniprotkb:KIAA1162(gene name synonym)|uniprotkb:TXNDC13(gene name synonym)|uniprotkb:Thioredoxin domain-containing protein 13(gene name synonym)|uniprotkb:PSEC0095(orf name)|uniprotkb:UNQ475/PRO938(orf name)|uniprotkb:TMX4(gene name)|psi-mi:TMX4(display_short) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Schiza et al. (2018) imex:IM-28077|pubmed:30097533 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-25504841|imex:IM-28077-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000131126(gene)|ensembl:ENST00000598265(transcript)|go:"GO:0001669"(acrosomal vesicle)|go:"GO:0002080"(acrosomal membrane)|go:"GO:0005576"(extracellular region)|go:"GO:0005886"(plasma membrane)|go:"GO:0007339"(binding of sperm to zona pellucida)|go:"GO:0009566"(fertilization)|go:"GO:0030317"(flagellated sperm motility)|go:"GO:0044853"(plasma membrane raft)|go:"GO:0046658"(anchored component of plasma membrane)|go:"GO:1901317"(regulation of flagellated sperm motility)|interpro:IPR016054(Ly-6 antigen / uPA receptor -like)|rcsb pdb:7BPR|reactome:R-HSA-163125|refseq:NP_001123483.1|refseq:NP_113639.4 refseq:NP_066979.2|ensembl:ENSG00000125827(gene)|ensembl:ENST00000246024(transcript)|go:"GO:0005637"(nuclear inner membrane)|go:"GO:0016021"(integral component of membrane)|interpro:IPR013766(Thioredoxin domain)|interpro:IPR017937|interpro:IPR036249 - - - figure legend:Supp Table S4 and Supp Fig. S3|comment:"Coimmunoprecipitation with 34ED229 (T2) anti-TEX101 antibody"|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-testis)|taxid:9606(Homo sapiens) - 2020/03/24 2020/06/18 rogid:ZE4tXTFi7lUCcIbCL4KHzY3a6xM9606 rogid:kibr+rQ3S/LSK3dOYtMNtOcIQ2k9606 rigid:2wTqH12DHkSLcixvnxiJPZhqAc0 false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9BY14 uniprotkb:P42704 intact:EBI-12549378|ensembl:ENSP00000472769|uniprotkb:Q7L5R2|uniprotkb:Q9BPY7 intact:EBI-1050853|uniprotkb:A0PJE3|uniprotkb:A8K1V1|uniprotkb:Q53PC0|uniprotkb:Q53QN7|uniprotkb:Q96D84|uniprotkb:Q6ZUD8|uniprotkb:Q7Z7A6|ensembl:ENSP00000260665 psi-mi:tx101_human(display_long)|uniprotkb:TEX101(gene name)|psi-mi:TEX101(display_short)|uniprotkb:Cell surface receptor NYD-SP8(gene name synonym)|uniprotkb:SGRG(gene name synonym)|uniprotkb:Scleroderma-associated autoantigen(gene name synonym)|uniprotkb:Spermatogenesis-related gene protein(gene name synonym)|uniprotkb:UNQ867/PRO1884(orf name) psi-mi:lpprc_human(display_long)|uniprotkb:130 kDa leucine-rich protein(gene name synonym)|uniprotkb:GP130(gene name synonym)|uniprotkb:LRPPRC(gene name)|psi-mi:LRPPRC(display_short)|uniprotkb:LRP130(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Schiza et al. (2018) imex:IM-28077|pubmed:30097533 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-25504841|imex:IM-28077-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000131126(gene)|ensembl:ENST00000598265(transcript)|go:"GO:0001669"(acrosomal vesicle)|go:"GO:0002080"(acrosomal membrane)|go:"GO:0005576"(extracellular region)|go:"GO:0005886"(plasma membrane)|go:"GO:0007339"(binding of sperm to zona pellucida)|go:"GO:0009566"(fertilization)|go:"GO:0030317"(flagellated sperm motility)|go:"GO:0044853"(plasma membrane raft)|go:"GO:0046658"(anchored component of plasma membrane)|go:"GO:1901317"(regulation of flagellated sperm motility)|interpro:IPR016054(Ly-6 antigen / uPA receptor -like)|rcsb pdb:7BPR|reactome:R-HSA-163125|refseq:NP_001123483.1|refseq:NP_113639.4 refseq:NP_573566.2|ensembl:ENSG00000138095(gene)|ensembl:ENST00000260665(transcript)|go:"GO:0000794"(condensed nuclear chromosome)|go:"GO:0000961"(negative regulation of mitochondrial RNA catabolic process)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005637"(nuclear inner membrane)|go:"GO:0005640"(nuclear outer membrane)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005874"(microtubule)|go:"GO:0008017"(microtubule binding)|go:"GO:0016020"(membrane)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0042645"(mitochondrial nucleoid)|go:"GO:0047497"(mitochondrion transport along microtubule)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0048487"(beta-tubulin binding)|go:"GO:0051028"(mRNA transport)|go:"GO:0070129"(regulation of mitochondrial translation)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR002885(Pentatricopeptide repeat)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR033443|interpro:IPR033490|mint:P42704|reactome:R-HSA-5628897|reactome:R-HSA-611105|reactome:R-HSA-9707564|dip:DIP-27543N - - - figure legend:Supp Table S4 and Supp Fig. S3|comment:"Coimmunoprecipitation with 34ED229 (T2) anti-TEX101 antibody"|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-testis)|taxid:9606(Homo sapiens) - 2020/03/24 2020/06/18 rogid:ZE4tXTFi7lUCcIbCL4KHzY3a6xM9606 rogid:U0ERiW4agkBDQ7iWXWgRQxhozkg9606 rigid:2wTqH12DHkSLcixvnxiJPZhqAc0 false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9BY14 uniprotkb:Q16563 intact:EBI-12549378|ensembl:ENSP00000472769|uniprotkb:Q7L5R2|uniprotkb:Q9BPY7 intact:EBI-2800683|uniprotkb:A4D0R2|uniprotkb:Q96AR8|ensembl:ENSP00000011473 psi-mi:tx101_human(display_long)|uniprotkb:TEX101(gene name)|psi-mi:TEX101(display_short)|uniprotkb:Cell surface receptor NYD-SP8(gene name synonym)|uniprotkb:SGRG(gene name synonym)|uniprotkb:Scleroderma-associated autoantigen(gene name synonym)|uniprotkb:Spermatogenesis-related gene protein(gene name synonym)|uniprotkb:UNQ867/PRO1884(orf name) psi-mi:sypl1_human(display_long)|uniprotkb:SYPL(gene name synonym)|uniprotkb:Pantophysin(gene name synonym)|uniprotkb:SYPL1(gene name)|psi-mi:SYPL1(display_short) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Schiza et al. (2018) imex:IM-28077|pubmed:30097533 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-25504841|imex:IM-28077-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000131126(gene)|ensembl:ENST00000598265(transcript)|go:"GO:0001669"(acrosomal vesicle)|go:"GO:0002080"(acrosomal membrane)|go:"GO:0005576"(extracellular region)|go:"GO:0005886"(plasma membrane)|go:"GO:0007339"(binding of sperm to zona pellucida)|go:"GO:0009566"(fertilization)|go:"GO:0030317"(flagellated sperm motility)|go:"GO:0044853"(plasma membrane raft)|go:"GO:0046658"(anchored component of plasma membrane)|go:"GO:1901317"(regulation of flagellated sperm motility)|interpro:IPR016054(Ly-6 antigen / uPA receptor -like)|rcsb pdb:7BPR|reactome:R-HSA-163125|refseq:NP_001123483.1|refseq:NP_113639.4 refseq:NP_006745.1|refseq:NP_874384.1|ensembl:ENSG00000008282(gene)|ensembl:ENST00000011473(transcript)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0007268"(chemical synaptic transmission)|go:"GO:0016021"(integral component of membrane)|go:"GO:0017075"(syntaxin-1 binding)|go:"GO:0030141"(secretory granule)|go:"GO:0030285"(integral component of synaptic vesicle membrane)|go:"GO:0030672"(synaptic vesicle membrane)|go:"GO:0042470"(melanosome)|go:"GO:0070062"(extracellular exosome)|interpro:IPR001285(Synaptophysin/synaptoporin)|interpro:IPR008253(Marvel) - - - figure legend:Supp Table S4 and Supp Fig. S3|comment:"Coimmunoprecipitation with 34ED229 (T2) anti-TEX101 antibody"|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-testis)|taxid:9606(Homo sapiens) - 2020/03/24 2020/06/18 rogid:ZE4tXTFi7lUCcIbCL4KHzY3a6xM9606 rogid:kw4EuKqd6PhotpKiicCjB99ZZCY9606 rigid:2wTqH12DHkSLcixvnxiJPZhqAc0 false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9BY14 uniprotkb:P46459 intact:EBI-12549378|ensembl:ENSP00000472769|uniprotkb:Q7L5R2|uniprotkb:Q9BPY7 intact:EBI-712251|ensembl:ENSP00000381293|ensembl:ENSP00000478614|ensembl:ENSP00000481714|uniprotkb:Q8N6D7|uniprotkb:Q9UKZ2|uniprotkb:A8K2D9|uniprotkb:B4DFA2 psi-mi:tx101_human(display_long)|uniprotkb:TEX101(gene name)|psi-mi:TEX101(display_short)|uniprotkb:Cell surface receptor NYD-SP8(gene name synonym)|uniprotkb:SGRG(gene name synonym)|uniprotkb:Scleroderma-associated autoantigen(gene name synonym)|uniprotkb:Spermatogenesis-related gene protein(gene name synonym)|uniprotkb:UNQ867/PRO1884(orf name) psi-mi:nsf_human(display_long)|uniprotkb:N-ethylmaleimide-sensitive fusion protein(gene name synonym)|uniprotkb:Vesicular-fusion protein NSF(gene name synonym)|uniprotkb:NSF(gene name)|psi-mi:NSF(display_short) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Schiza et al. (2018) imex:IM-28077|pubmed:30097533 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-25504841|imex:IM-28077-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000131126(gene)|ensembl:ENST00000598265(transcript)|go:"GO:0001669"(acrosomal vesicle)|go:"GO:0002080"(acrosomal membrane)|go:"GO:0005576"(extracellular region)|go:"GO:0005886"(plasma membrane)|go:"GO:0007339"(binding of sperm to zona pellucida)|go:"GO:0009566"(fertilization)|go:"GO:0030317"(flagellated sperm motility)|go:"GO:0044853"(plasma membrane raft)|go:"GO:0046658"(anchored component of plasma membrane)|go:"GO:1901317"(regulation of flagellated sperm motility)|interpro:IPR016054(Ly-6 antigen / uPA receptor -like)|rcsb pdb:7BPR|reactome:R-HSA-163125|refseq:NP_001123483.1|refseq:NP_113639.4 ensembl:ENSG00000073969(gene)|ensembl:ENSG00000276262(gene)|ensembl:ENSG00000278174(gene)|ensembl:ENST00000398238(transcript)|ensembl:ENST00000611398(transcript)|ensembl:ENST00000620290(transcript)|go:"GO:0000149"(SNARE binding)|go:"GO:0001921"(positive regulation of receptor recycling)|go:"GO:0005524"(ATP binding)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005795"(Golgi stack)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006813"(potassium ion transport)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006887"(exocytosis)|go:"GO:0006891"(intra-Golgi vesicle-mediated transport)|go:"GO:0014069"(postsynaptic density)|go:"GO:0016192"(vesicle-mediated transport)|go:"GO:0017075"(syntaxin-1 binding)|go:"GO:0017157"(regulation of exocytosis)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030165"(PDZ domain binding)|go:"GO:0035255"(ionotropic glutamate receptor binding)|go:"GO:0035494"(SNARE complex disassembly)|go:"GO:0043001"(Golgi to plasma membrane protein transport)|go:"GO:0043198"(dendritic shaft)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045026"(plasma membrane fusion)|go:"GO:0045732"(positive regulation of protein catabolic process)|go:"GO:0046872"(metal ion binding)|go:"GO:0048211"(Golgi vesicle docking)|go:"GO:0140545"(protein disaggregase activity)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|interpro:IPR003338(AAA ATPase VAT, N-terminal)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR003959(AAA ATPase, core)|interpro:IPR003960(AAA ATPase, conserved site)|interpro:IPR004201(Cell division protein 48, CDC48, domain 2)|interpro:IPR009010(Aspartate decarboxylase-like fold)|interpro:IPR027417|interpro:IPR029067|interpro:IPR039812|interpro:IPR041569|mint:P46459|rcsb pdb:6KZQ|reactome:R-HSA-204005|reactome:R-HSA-416993|reactome:R-HSA-6807878|reactome:R-HSA-6811434|reactome:R-HSA-6811438|reactome:R-HSA-6811440|refseq:NP_006169.2 - - - figure legend:Supp Table S4 and Supp Fig. S3|comment:"Coimmunoprecipitation with 34ED229 (T2) anti-TEX101 antibody"|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-testis)|taxid:9606(Homo sapiens) - 2020/03/24 2020/06/18 rogid:ZE4tXTFi7lUCcIbCL4KHzY3a6xM9606 rogid:J5hsoA0RTiQkWrV7nWpnK8Dvxxg9606 rigid:2wTqH12DHkSLcixvnxiJPZhqAc0 false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9BY14 uniprotkb:Q8WUM4 intact:EBI-12549378|ensembl:ENSP00000472769|uniprotkb:Q7L5R2|uniprotkb:Q9BPY7 intact:EBI-310624|uniprotkb:Q9BX86|uniprotkb:Q9NUN0|uniprotkb:Q9P2H2|uniprotkb:Q9UKL5|uniprotkb:C5MQH7|intact:EBI-10971645|uniprotkb:E9PFU1|uniprotkb:Q6NUS1|ensembl:ENSP00000307387|intact:EBI-28983290 psi-mi:tx101_human(display_long)|uniprotkb:TEX101(gene name)|psi-mi:TEX101(display_short)|uniprotkb:Cell surface receptor NYD-SP8(gene name synonym)|uniprotkb:SGRG(gene name synonym)|uniprotkb:Scleroderma-associated autoantigen(gene name synonym)|uniprotkb:Spermatogenesis-related gene protein(gene name synonym)|uniprotkb:UNQ867/PRO1884(orf name) psi-mi:pdc6i_human(display_long)|uniprotkb:PDCD6IP(gene name)|psi-mi:PDCD6IP(display_short)|uniprotkb:AIP1(gene name synonym)|uniprotkb:KIAA1375(gene name synonym)|uniprotkb:ALIX(gene name synonym)|uniprotkb:ALG-2-interacting protein 1(gene name synonym)|uniprotkb:Hp95(gene name synonym)|uniprotkb:ALG-2-interacting protein X(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Schiza et al. (2018) imex:IM-28077|pubmed:30097533 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-25504841|imex:IM-28077-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000131126(gene)|ensembl:ENST00000598265(transcript)|go:"GO:0001669"(acrosomal vesicle)|go:"GO:0002080"(acrosomal membrane)|go:"GO:0005576"(extracellular region)|go:"GO:0005886"(plasma membrane)|go:"GO:0007339"(binding of sperm to zona pellucida)|go:"GO:0009566"(fertilization)|go:"GO:0030317"(flagellated sperm motility)|go:"GO:0044853"(plasma membrane raft)|go:"GO:0046658"(anchored component of plasma membrane)|go:"GO:1901317"(regulation of flagellated sperm motility)|interpro:IPR016054(Ly-6 antigen / uPA receptor -like)|rcsb pdb:7BPR|reactome:R-HSA-163125|refseq:NP_001123483.1|refseq:NP_113639.4 refseq:NP_037506.2|ensembl:ENSP00000307387|ensembl:ENST00000457054|ensembl:ENSP00000411825|refseq:NP_001155901.1|ensembl:ENSG00000170248(gene)|ensembl:ENST00000307296(transcript)|go:"GO:0000281"(mitotic cytokinesis)|go:"GO:0000915"(actomyosin contractile ring assembly)|go:"GO:0001772"(immunological synapse)|go:"GO:0005815"(microtubule organizing center)|go:"GO:0005829"(cytosol)|go:"GO:0005923"(bicellular tight junction)|go:"GO:0005925"(focal adhesion)|go:"GO:0006915"(apoptotic process)|go:"GO:0010824"(regulation of centrosome duplication)|go:"GO:0015031"(protein transport)|go:"GO:0016020"(membrane)|go:"GO:0031871"(proteinase activated receptor binding)|go:"GO:0036258"(multivesicular body assembly)|go:"GO:0039702"(viral budding via host ESCRT complex)|go:"GO:0042470"(melanosome)|go:"GO:0042641"(actomyosin)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0045199"(maintenance of epithelial cell apical/basal polarity)|go:"GO:0046755"(viral budding)|go:"GO:0048306"(calcium-dependent protein binding)|go:"GO:0051260"(protein homooligomerization)|go:"GO:0061952"(midbody abscission)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070830"(bicellular tight junction assembly)|go:"GO:0070971"(endoplasmic reticulum exit site)|go:"GO:0090543"(Flemming body)|go:"GO:0090559"(regulation of membrane permeability)|go:"GO:0090611"(ubiquitin-independent protein catabolic process via the multivesicular body sorting pathway)|go:"GO:1903543"(positive regulation of exosomal secretion)|go:"GO:1903551"(regulation of extracellular exosome assembly)|go:"GO:1903553"(positive regulation of extracellular exosome assembly)|go:"GO:1903561"(extracellular vesicle)|interpro:IPR004328(BRO1)|interpro:IPR025304|interpro:IPR038499|mint:Q8WUM4|rcsb pdb:2OEV|rcsb pdb:2OEW|rcsb pdb:2OEX|rcsb pdb:2OJQ|rcsb pdb:2R02|rcsb pdb:2R03|rcsb pdb:2R05|rcsb pdb:2XS1|rcsb pdb:2XS8|rcsb pdb:2ZNE|rcsb pdb:3C3O|rcsb pdb:3C3Q|rcsb pdb:3C3R|rcsb pdb:3E1R|rcsb pdb:3WUV|rcsb pdb:4JJY|rcsb pdb:5V3R|rcsb pdb:5WA1|rcsb pdb:6KP3|reactome:R-HSA-162588|reactome:R-HSA-5210891|reactome:R-HSA-5213460|reactome:R-HSA-5675482|refseq:NP_001243121.1|dip:DIP-29327N - - - figure legend:Supp Table S4 and Supp Fig. S3|comment:"Coimmunoprecipitation with 34ED229 (T2) anti-TEX101 antibody"|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-testis)|taxid:9606(Homo sapiens) - 2020/03/24 2020/06/18 rogid:ZE4tXTFi7lUCcIbCL4KHzY3a6xM9606 rogid:FYD19EyMBAGl204Xlgr4MlE8GMs9606 rigid:2wTqH12DHkSLcixvnxiJPZhqAc0 false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9BY14 uniprotkb:P50454 intact:EBI-12549378|ensembl:ENSP00000472769|uniprotkb:Q7L5R2|uniprotkb:Q9BPY7 intact:EBI-350723|uniprotkb:P29043|uniprotkb:Q5XPB4|uniprotkb:Q6NSJ6|uniprotkb:Q8IY96|uniprotkb:Q9NP88|uniprotkb:B3KVJ3|ensembl:ENSP00000350894|ensembl:ENSP00000434412|ensembl:ENSP00000434657 psi-mi:tx101_human(display_long)|uniprotkb:TEX101(gene name)|psi-mi:TEX101(display_short)|uniprotkb:Cell surface receptor NYD-SP8(gene name synonym)|uniprotkb:SGRG(gene name synonym)|uniprotkb:Scleroderma-associated autoantigen(gene name synonym)|uniprotkb:Spermatogenesis-related gene protein(gene name synonym)|uniprotkb:UNQ867/PRO1884(orf name) psi-mi:serph_human(display_long)|uniprotkb:SERPINH1(gene name)|psi-mi:SERPINH1(display_short)|uniprotkb:CBP2(gene name synonym)|uniprotkb:Collagen-binding protein(gene name synonym)|uniprotkb:47 kDa heat shock protein(gene name synonym)|uniprotkb:Rheumatoid arthritis-related antigen RA-A47(gene name synonym)|uniprotkb:Arsenic-transactivated protein 3(gene name synonym)|uniprotkb:Cell proliferation-inducing gene 14 protein(gene name synonym)|uniprotkb:CBP1(gene name synonym)|uniprotkb:HSP47(gene name synonym)|uniprotkb:SERPINH2(gene name synonym)|uniprotkb:PIG14(orf name) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Schiza et al. (2018) imex:IM-28077|pubmed:30097533 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-25504841|imex:IM-28077-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000131126(gene)|ensembl:ENST00000598265(transcript)|go:"GO:0001669"(acrosomal vesicle)|go:"GO:0002080"(acrosomal membrane)|go:"GO:0005576"(extracellular region)|go:"GO:0005886"(plasma membrane)|go:"GO:0007339"(binding of sperm to zona pellucida)|go:"GO:0009566"(fertilization)|go:"GO:0030317"(flagellated sperm motility)|go:"GO:0044853"(plasma membrane raft)|go:"GO:0046658"(anchored component of plasma membrane)|go:"GO:1901317"(regulation of flagellated sperm motility)|interpro:IPR016054(Ly-6 antigen / uPA receptor -like)|rcsb pdb:7BPR|reactome:R-HSA-163125|refseq:NP_001123483.1|refseq:NP_113639.4 refseq:NP_001193943.1|refseq:NP_001226.2|go:"GO:0003723"(RNA binding)|go:"GO:0004867"(serine-type endopeptidase inhibitor activity)|go:"GO:0005518"(collagen binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005788"(endoplasmic reticulum lumen)|go:"GO:0005793"(endoplasmic reticulum-Golgi intermediate compartment)|go:"GO:0006986"(response to unfolded protein)|go:"GO:0010951"(negative regulation of endopeptidase activity)|go:"GO:0030199"(collagen fibril organization)|go:"GO:0032964"(collagen biosynthetic process)|go:"GO:0045121"(membrane raft)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0051604"(protein maturation)|go:"GO:0062023"(collagen-containing extracellular matrix)|interpro:IPR000215(Protease inhibitor I4, serpin)|interpro:IPR023795|interpro:IPR023796|interpro:IPR033547|interpro:IPR033830|interpro:IPR036186|interpro:IPR042178|interpro:IPR042185|mint:P50454|reactome:R-HSA-1650814|ensembl:ENSG00000149257(gene)|ensembl:ENST00000358171(transcript)|ensembl:ENST00000524558(transcript)|ensembl:ENST00000533603(transcript)|go:"GO:0003433"(chondrocyte development involved in endochondral bone morphogenesis)|refseq:XP_011543629.1 - - - figure legend:Supp Table S4 and Supp Fig. S3|comment:"Coimmunoprecipitation with 34ED229 (T2) anti-TEX101 antibody"|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-testis)|taxid:9606(Homo sapiens) - 2020/03/24 2020/06/18 rogid:ZE4tXTFi7lUCcIbCL4KHzY3a6xM9606 rogid:cO3NR2hb0NyOs99Sq1aODePlDR09606 rigid:2wTqH12DHkSLcixvnxiJPZhqAc0 false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9BY14 uniprotkb:Q9BWD1 intact:EBI-12549378|ensembl:ENSP00000472769|uniprotkb:Q7L5R2|uniprotkb:Q9BPY7 intact:EBI-1047273|uniprotkb:E1P5B1|uniprotkb:Q16146|uniprotkb:Q5TCL7|uniprotkb:Q8TDM4|uniprotkb:B7Z233|ensembl:ENSP00000356015 psi-mi:tx101_human(display_long)|uniprotkb:TEX101(gene name)|psi-mi:TEX101(display_short)|uniprotkb:Cell surface receptor NYD-SP8(gene name synonym)|uniprotkb:SGRG(gene name synonym)|uniprotkb:Scleroderma-associated autoantigen(gene name synonym)|uniprotkb:Spermatogenesis-related gene protein(gene name synonym)|uniprotkb:UNQ867/PRO1884(orf name) psi-mi:thic_human(display_long)|uniprotkb:Cytosolic acetoacetyl-CoA thiolase(gene name synonym)|uniprotkb:Acetyl-CoA transferase-like protein(gene name synonym)|uniprotkb:ACAT2(gene name)|psi-mi:ACAT2(display_short)|uniprotkb:ACTL(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Schiza et al. (2018) imex:IM-28077|pubmed:30097533 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-25504841|imex:IM-28077-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000131126(gene)|ensembl:ENST00000598265(transcript)|go:"GO:0001669"(acrosomal vesicle)|go:"GO:0002080"(acrosomal membrane)|go:"GO:0005576"(extracellular region)|go:"GO:0005886"(plasma membrane)|go:"GO:0007339"(binding of sperm to zona pellucida)|go:"GO:0009566"(fertilization)|go:"GO:0030317"(flagellated sperm motility)|go:"GO:0044853"(plasma membrane raft)|go:"GO:0046658"(anchored component of plasma membrane)|go:"GO:1901317"(regulation of flagellated sperm motility)|interpro:IPR016054(Ly-6 antigen / uPA receptor -like)|rcsb pdb:7BPR|reactome:R-HSA-163125|refseq:NP_001123483.1|refseq:NP_113639.4 refseq:NP_005882.2|refseq:NP_001290182.1|ensembl:ENSG00000120437(gene)|ensembl:ENST00000367048(transcript)|go:"GO:0003985"(acetyl-CoA C-acetyltransferase activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0006629"(lipid metabolic process)|go:"GO:0006635"(fatty acid beta-oxidation)|go:"GO:0070062"(extracellular exosome)|interpro:IPR002155(Thiolase)|interpro:IPR016039(Thiolase-like)|interpro:IPR020610|interpro:IPR020613|interpro:IPR020616|interpro:IPR020617|rcsb pdb:1WL4|rcsb pdb:1WL5|reactome:R-HSA-191273 - - - figure legend:Supp Table S4 and Supp Fig. S3|comment:"Coimmunoprecipitation with 34ED229 (T2) anti-TEX101 antibody"|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-testis)|taxid:9606(Homo sapiens) - 2020/03/24 2020/06/18 rogid:ZE4tXTFi7lUCcIbCL4KHzY3a6xM9606 rogid:JW66UFxxwRH0wEuVjCyB0MFNZl49606 rigid:2wTqH12DHkSLcixvnxiJPZhqAc0 false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9BY14 uniprotkb:P60033 intact:EBI-12549378|ensembl:ENSP00000472769|uniprotkb:Q7L5R2|uniprotkb:Q9BPY7 intact:EBI-712921|ensembl:ENSP00000263645|uniprotkb:P18582|uniprotkb:Q5U0J6 psi-mi:tx101_human(display_long)|uniprotkb:TEX101(gene name)|psi-mi:TEX101(display_short)|uniprotkb:Cell surface receptor NYD-SP8(gene name synonym)|uniprotkb:SGRG(gene name synonym)|uniprotkb:Scleroderma-associated autoantigen(gene name synonym)|uniprotkb:Spermatogenesis-related gene protein(gene name synonym)|uniprotkb:UNQ867/PRO1884(orf name) psi-mi:cd81_human(display_long)|uniprotkb:26 kDa cell surface protein TAPA-1(gene name synonym)|uniprotkb:Target of the antiproliferative antibody 1(gene name synonym)|uniprotkb:Tetraspanin-28(gene name synonym)|uniprotkb:CD81(gene name)|psi-mi:CD81(display_short)|uniprotkb:TAPA1(gene name synonym)|uniprotkb:TSPAN28(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Schiza et al. (2018) imex:IM-28077|pubmed:30097533 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-25504841|imex:IM-28077-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000131126(gene)|ensembl:ENST00000598265(transcript)|go:"GO:0001669"(acrosomal vesicle)|go:"GO:0002080"(acrosomal membrane)|go:"GO:0005576"(extracellular region)|go:"GO:0005886"(plasma membrane)|go:"GO:0007339"(binding of sperm to zona pellucida)|go:"GO:0009566"(fertilization)|go:"GO:0030317"(flagellated sperm motility)|go:"GO:0044853"(plasma membrane raft)|go:"GO:0046658"(anchored component of plasma membrane)|go:"GO:1901317"(regulation of flagellated sperm motility)|interpro:IPR016054(Ly-6 antigen / uPA receptor -like)|rcsb pdb:7BPR|reactome:R-HSA-163125|refseq:NP_001123483.1|refseq:NP_113639.4 ensembl:ENSG00000110651(gene)|ensembl:ENST00000263645(transcript)|go:"GO:0000187"(obsolete activation of MAPK activity)|go:"GO:0001618"(virus receptor activity)|go:"GO:0001771"(immunological synapse formation)|go:"GO:0001772"(immunological synapse)|go:"GO:0002455"(humoral immune response mediated by circulating immunoglobulin)|go:"GO:0002863"(positive regulation of inflammatory response to antigenic stimulus)|go:"GO:0005178"(integrin binding)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0005925"(focal adhesion)|go:"GO:0008104"(protein localization)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0009925"(basal plasma membrane)|go:"GO:0014905"(myoblast fusion involved in skeletal muscle regeneration)|go:"GO:0015485"(cholesterol binding)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0023026"(MHC class II protein complex binding)|go:"GO:0030890"(positive regulation of B cell proliferation)|go:"GO:0031623"(receptor internalization)|go:"GO:0031647"(regulation of protein stability)|go:"GO:0031982"(vesicle)|go:"GO:0034238"(macrophage fusion)|go:"GO:0035783"(CD4-positive, alpha-beta T cell costimulation)|go:"GO:0042289"(MHC class II protein binding)|go:"GO:0043128"(positive regulation of 1-phosphatidylinositol 4-kinase activity)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046718"(viral entry into host cell)|go:"GO:0046813"(receptor-mediated virion attachment to host cell)|go:"GO:0050731"(positive regulation of peptidyl-tyrosine phosphorylation)|go:"GO:0050861"(positive regulation of B cell receptor signaling pathway)|go:"GO:0050862"(positive regulation of T cell receptor signaling pathway)|go:"GO:0061462"(protein localization to lysosome)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070863"(positive regulation of protein exit from endoplasmic reticulum)|go:"GO:0071404"(cellular response to low-density lipoprotein particle stimulus)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0072675"(osteoclast fusion)|go:"GO:0097197"(tetraspanin-enriched microdomain)|go:"GO:1903911"(positive regulation of receptor clustering)|go:"GO:1904352"(positive regulation of protein catabolic process in the vacuole)|go:"GO:1905521"(regulation of macrophage migration)|go:"GO:1905676"(positive regulation of adaptive immune memory response)|go:"GO:1990459"(transferrin receptor binding)|go:"GO:2000553"(positive regulation of T-helper 2 cell cytokine production)|go:"GO:2000563"(positive regulation of CD4-positive, alpha-beta T cell proliferation)|go:"GO:2001190"(positive regulation of T cell activation via T cell receptor contact with antigen bound to MHC molecule on antigen presenting cell)|interpro:IPR000301(CD9/CD37/CD63 antigen)|interpro:IPR008952(Tetraspanin)|interpro:IPR018499|interpro:IPR018503|mint:P60033|rcsb pdb:1G8Q|rcsb pdb:1IV5|rcsb pdb:2AVZ|rcsb pdb:3X0E|rcsb pdb:5DFV|rcsb pdb:5DFW|rcsb pdb:5M2C|rcsb pdb:5M33|rcsb pdb:5M3D|rcsb pdb:5M3T|rcsb pdb:5M4R|rcsb pdb:5TCX|rcsb pdb:6EJG|rcsb pdb:6EJM|rcsb pdb:6EK2|rcsb pdb:6U9S|rcsb pdb:7JIC|reactome:R-HSA-198933|reactome:R-HSA-977606|refseq:NP_004347.1|refseq:NP_001284578.1 - - - figure legend:Supp Table S4 and Supp Fig. S3|comment:"Coimmunoprecipitation with 34ED229 (T2) anti-TEX101 antibody"|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-testis)|taxid:9606(Homo sapiens) - 2020/03/24 2020/06/18 rogid:ZE4tXTFi7lUCcIbCL4KHzY3a6xM9606 rogid:LPDYYmkI2TtoCarkcBXuaibfB6A9606 rigid:2wTqH12DHkSLcixvnxiJPZhqAc0 false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9BY14 uniprotkb:P17858 intact:EBI-12549378|ensembl:ENSP00000472769|uniprotkb:Q7L5R2|uniprotkb:Q9BPY7 intact:EBI-487243|uniprotkb:Q96A64|uniprotkb:Q96IH4|uniprotkb:Q9BR91|ensembl:ENSP00000269848 psi-mi:tx101_human(display_long)|uniprotkb:TEX101(gene name)|psi-mi:TEX101(display_short)|uniprotkb:Cell surface receptor NYD-SP8(gene name synonym)|uniprotkb:SGRG(gene name synonym)|uniprotkb:Scleroderma-associated autoantigen(gene name synonym)|uniprotkb:Spermatogenesis-related gene protein(gene name synonym)|uniprotkb:UNQ867/PRO1884(orf name) psi-mi:pfkal_human(display_long)|uniprotkb:PFKL(gene name)|psi-mi:PFKL(display_short)|uniprotkb:Phosphohexokinase(gene name synonym)|uniprotkb:Phosphofructo-1-kinase isozyme B(gene name synonym)|uniprotkb:6-phosphofructokinase type B(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Schiza et al. (2018) imex:IM-28077|pubmed:30097533 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-25504841|imex:IM-28077-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000131126(gene)|ensembl:ENST00000598265(transcript)|go:"GO:0001669"(acrosomal vesicle)|go:"GO:0002080"(acrosomal membrane)|go:"GO:0005576"(extracellular region)|go:"GO:0005886"(plasma membrane)|go:"GO:0007339"(binding of sperm to zona pellucida)|go:"GO:0009566"(fertilization)|go:"GO:0030317"(flagellated sperm motility)|go:"GO:0044853"(plasma membrane raft)|go:"GO:0046658"(anchored component of plasma membrane)|go:"GO:1901317"(regulation of flagellated sperm motility)|interpro:IPR016054(Ly-6 antigen / uPA receptor -like)|rcsb pdb:7BPR|reactome:R-HSA-163125|refseq:NP_001123483.1|refseq:NP_113639.4 refseq:NP_001002021.2|refseq:NP_002617.3|go:"GO:0006002"(fructose 6-phosphate metabolic process)|go:"GO:0006096"(glycolytic process)|go:"GO:0009749"(response to glucose)|go:"GO:0016020"(membrane)|go:"GO:0016208"(AMP binding)|go:"GO:0019900"(kinase binding)|go:"GO:0030388"(fructose 1,6-bisphosphate metabolic process)|go:"GO:0070062"(extracellular exosome)|go:"GO:0034774"(secretory granule lumen)|go:"GO:0070095"(fructose-6-phosphate binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0046676"(negative regulation of insulin secretion)|go:"GO:0046872"(metal ion binding)|go:"GO:0048029"(monosaccharide binding)|go:"GO:0061621"(canonical glycolysis)|go:"GO:0070061"(fructose binding)|go:"GO:1904813"(ficolin-1-rich granule lumen)|interpro:IPR000023(Phosphofructokinase)|interpro:IPR009161(6-phosphofructokinase, eukaryotic type)|interpro:IPR015912(Phosphofructokinase, conserved site)|interpro:IPR022953|interpro:IPR035966|interpro:IPR041914|mint:P17858|reactome:R-HSA-6798695|reactome:R-HSA-70171|ensembl:ENSG00000141959(gene)|ensembl:ENST00000349048(transcript)|go:"GO:0003872"(6-phosphofructokinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005829"(cytosol)|go:"GO:0005945"(6-phosphofructokinase complex) - - - figure legend:Supp Table S4 and Supp Fig. S3|comment:"Coimmunoprecipitation with 34ED229 (T2) anti-TEX101 antibody"|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-testis)|taxid:9606(Homo sapiens) - 2020/03/24 2020/06/18 rogid:ZE4tXTFi7lUCcIbCL4KHzY3a6xM9606 rogid:lP9/V5WcCl5rLpy4QEZnWkLCCcQ9606 rigid:2wTqH12DHkSLcixvnxiJPZhqAc0 false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9BY14 uniprotkb:P52907 intact:EBI-12549378|ensembl:ENSP00000472769|uniprotkb:Q7L5R2|uniprotkb:Q9BPY7 intact:EBI-355586|uniprotkb:Q53FQ6|uniprotkb:Q6FHD5|ensembl:ENSP00000263168 psi-mi:tx101_human(display_long)|uniprotkb:TEX101(gene name)|psi-mi:TEX101(display_short)|uniprotkb:Cell surface receptor NYD-SP8(gene name synonym)|uniprotkb:SGRG(gene name synonym)|uniprotkb:Scleroderma-associated autoantigen(gene name synonym)|uniprotkb:Spermatogenesis-related gene protein(gene name synonym)|uniprotkb:UNQ867/PRO1884(orf name) psi-mi:caza1_human(display_long)|uniprotkb:CAPZA1(gene name)|psi-mi:CAPZA1(display_short)|uniprotkb:CapZ alpha-1(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Schiza et al. (2018) imex:IM-28077|pubmed:30097533 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-25504841|imex:IM-28077-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000131126(gene)|ensembl:ENST00000598265(transcript)|go:"GO:0001669"(acrosomal vesicle)|go:"GO:0002080"(acrosomal membrane)|go:"GO:0005576"(extracellular region)|go:"GO:0005886"(plasma membrane)|go:"GO:0007339"(binding of sperm to zona pellucida)|go:"GO:0009566"(fertilization)|go:"GO:0030317"(flagellated sperm motility)|go:"GO:0044853"(plasma membrane raft)|go:"GO:0046658"(anchored component of plasma membrane)|go:"GO:1901317"(regulation of flagellated sperm motility)|interpro:IPR016054(Ly-6 antigen / uPA receptor -like)|rcsb pdb:7BPR|reactome:R-HSA-163125|refseq:NP_001123483.1|refseq:NP_113639.4 refseq:NP_006126.1|ensembl:ENSG00000116489(gene)|ensembl:ENST00000263168(transcript)|go:"GO:0003779"(actin binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0008290"(F-actin capping protein complex)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0030036"(actin cytoskeleton organization)|go:"GO:0034329"(cell junction assembly)|go:"GO:0045296"(cadherin binding)|go:"GO:0051015"(actin filament binding)|go:"GO:0051016"(barbed-end actin filament capping)|go:"GO:0065003"(protein-containing complex assembly)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071203"(WASH complex)|interpro:IPR002189(F-actin capping protein, alpha subunit)|interpro:IPR017865|interpro:IPR037282|interpro:IPR042276|interpro:IPR042489|mint:P52907|rcsb pdb:1MQ1|rcsb pdb:1MWN|reactome:R-HSA-2132295|reactome:R-HSA-3371497|reactome:R-HSA-6807878|reactome:R-HSA-6811436|reactome:R-HSA-879415|reactome:R-HSA-8950505|reactome:R-HSA-9662360|reactome:R-HSA-983231 - - - figure legend:Supp Table S4 and Supp Fig. S3|comment:"Coimmunoprecipitation with 34ED229 (T2) anti-TEX101 antibody"|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-testis)|taxid:9606(Homo sapiens) - 2020/03/24 2020/06/18 rogid:ZE4tXTFi7lUCcIbCL4KHzY3a6xM9606 rogid:97S4WPtjgt4MDLoptRhQ2yH8UNE9606 rigid:2wTqH12DHkSLcixvnxiJPZhqAc0 false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9BY14 uniprotkb:Q13618 intact:EBI-12549378|ensembl:ENSP00000472769|uniprotkb:Q7L5R2|uniprotkb:Q9BPY7 intact:EBI-456129|uniprotkb:O75415|uniprotkb:Q569L3|uniprotkb:Q9UBI8|uniprotkb:B8ZZC3|uniprotkb:Q9UET7|uniprotkb:A8K536|ensembl:ENSP00000264414 psi-mi:tx101_human(display_long)|uniprotkb:TEX101(gene name)|psi-mi:TEX101(display_short)|uniprotkb:Cell surface receptor NYD-SP8(gene name synonym)|uniprotkb:SGRG(gene name synonym)|uniprotkb:Scleroderma-associated autoantigen(gene name synonym)|uniprotkb:Spermatogenesis-related gene protein(gene name synonym)|uniprotkb:UNQ867/PRO1884(orf name) psi-mi:cul3_human(display_long)|uniprotkb:CUL3(gene name)|psi-mi:CUL3(display_short)|uniprotkb:KIAA0617(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Schiza et al. (2018) imex:IM-28077|pubmed:30097533 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-25504841|imex:IM-28077-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000131126(gene)|ensembl:ENST00000598265(transcript)|go:"GO:0001669"(acrosomal vesicle)|go:"GO:0002080"(acrosomal membrane)|go:"GO:0005576"(extracellular region)|go:"GO:0005886"(plasma membrane)|go:"GO:0007339"(binding of sperm to zona pellucida)|go:"GO:0009566"(fertilization)|go:"GO:0030317"(flagellated sperm motility)|go:"GO:0044853"(plasma membrane raft)|go:"GO:0046658"(anchored component of plasma membrane)|go:"GO:1901317"(regulation of flagellated sperm motility)|interpro:IPR016054(Ly-6 antigen / uPA receptor -like)|rcsb pdb:7BPR|reactome:R-HSA-163125|refseq:NP_001123483.1|refseq:NP_113639.4 refseq:NP_003581.1|refseq:NP_001244126.1|refseq:NP_001244127.1|dip:DIP-31611N|ensembl:ENSG00000036257(gene)|ensembl:ENST00000264414(transcript)|go:"GO:0000082"(G1/S transition of mitotic cell cycle)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0000922"(spindle pole)|go:"GO:0001831"(trophectodermal cellular morphogenesis)|go:"GO:0005112"(Notch binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005813"(centrosome)|go:"GO:0005827"(polar microtubule)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0006513"(protein monoubiquitination)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0007080"(mitotic metaphase plate congression)|go:"GO:0007229"(integrin-mediated signaling pathway)|go:"GO:0007369"(gastrulation)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0016020"(membrane)|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0016477"(cell migration)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0017145"(stem cell division)|go:"GO:0030030"(cell projection organization)|go:"GO:0030332"(cyclin binding)|go:"GO:0031145"(anaphase-promoting complex-dependent catabolic process)|go:"GO:0031208"(POZ domain binding)|go:"GO:0031398"(positive regulation of protein ubiquitination)|go:"GO:0031461"(cullin-RING ubiquitin ligase complex)|go:"GO:0031463"(Cul3-RING ubiquitin ligase complex)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0031648"(protein destabilization)|go:"GO:0032467"(positive regulation of cytokinesis)|go:"GO:0035024"(negative regulation of Rho protein signal transduction)|go:"GO:0036126"(sperm flagellum)|go:"GO:0040016"(embryonic cleavage)|go:"GO:0042802"(identical protein binding)|go:"GO:0043149"(stress fiber assembly)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0044346"(fibroblast apoptotic process)|go:"GO:0045842"(positive regulation of mitotic metaphase/anaphase transition)|go:"GO:0048208"(COPII vesicle coating)|go:"GO:0051865"(protein autoubiquitination)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070936"(protein K48-linked ubiquitination)|go:"GO:0071630"(nuclear protein quality control by the ubiquitin-proteasome system)|go:"GO:0072576"(liver morphogenesis)|go:"GO:0072686"(mitotic spindle)|go:"GO:0097193"(intrinsic apoptotic signaling pathway)|go:"GO:1901992"(positive regulation of mitotic cell cycle phase transition)|interpro:IPR001373(Cullin, N-terminal region)|interpro:IPR016157(Cullin, conserved site)|interpro:IPR016158(Cullin homology)|interpro:IPR016159(Cullin repeat-like)|interpro:IPR019559|interpro:IPR036317|interpro:IPR036388|interpro:IPR036390|mint:Q13618|rcsb pdb:2MYL|rcsb pdb:2MYM|rcsb pdb:4AP2|rcsb pdb:4APF|rcsb pdb:4EOZ|rcsb pdb:4HXI|rcsb pdb:5NLB|rcsb pdb:6I2M|reactome:R-HSA-4641258|reactome:R-HSA-5632684|reactome:R-HSA-5658442|reactome:R-HSA-8932339|reactome:R-HSA-8951664|reactome:R-HSA-9013418|reactome:R-HSA-9013422|reactome:R-HSA-9706019|reactome:R-HSA-983168 - - - figure legend:Supp Table S4 and Supp Fig. S3|comment:"Coimmunoprecipitation with 34ED229 (T2) anti-TEX101 antibody"|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-testis)|taxid:9606(Homo sapiens) - 2020/03/24 2020/06/18 rogid:ZE4tXTFi7lUCcIbCL4KHzY3a6xM9606 rogid:xI/8pHB9nckOW629STOqKba4KzQ9606 rigid:2wTqH12DHkSLcixvnxiJPZhqAc0 false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9BY14 uniprotkb:P13010 intact:EBI-12549378|ensembl:ENSP00000472769|uniprotkb:Q7L5R2|uniprotkb:Q9BPY7 intact:EBI-357997|uniprotkb:A8K3X5|uniprotkb:Q0Z7V0|uniprotkb:Q53HH7|uniprotkb:Q7M4N0|uniprotkb:Q4VBQ5|uniprotkb:Q9UCQ0|uniprotkb:Q9UCQ1|ensembl:ENSP00000375977|ensembl:ENSP00000375978 psi-mi:tx101_human(display_long)|uniprotkb:TEX101(gene name)|psi-mi:TEX101(display_short)|uniprotkb:Cell surface receptor NYD-SP8(gene name synonym)|uniprotkb:SGRG(gene name synonym)|uniprotkb:Scleroderma-associated autoantigen(gene name synonym)|uniprotkb:Spermatogenesis-related gene protein(gene name synonym)|uniprotkb:UNQ867/PRO1884(orf name) psi-mi:xrcc5_human(display_long)|uniprotkb:XRCC5(gene name)|psi-mi:XRCC5(display_short)|uniprotkb:G22P2(gene name synonym)|uniprotkb:ATP-dependent DNA helicase II 80 kDa subunit(gene name synonym)|uniprotkb:Lupus Ku autoantigen protein p86(gene name synonym)|uniprotkb:86 kDa subunit of Ku antigen(gene name synonym)|uniprotkb:Ku86(gene name synonym)|uniprotkb:Ku80(gene name synonym)|uniprotkb:Thyroid-lupus autoantigen(gene name synonym)|uniprotkb:CTC box-binding factor 85 kDa subunit(gene name synonym)|uniprotkb:Nuclear factor IV(gene name synonym)|uniprotkb:DNA repair protein XRCC5(gene name synonym)|uniprotkb:"X-ray repair complementing defective repair in Chinese hamster cells 5 (double-strand-break rejoining)"(gene name synonym)|uniprotkb:ATP-dependent DNA helicase 2 subunit 2(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Schiza et al. (2018) imex:IM-28077|pubmed:30097533 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-25504841|imex:IM-28077-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000131126(gene)|ensembl:ENST00000598265(transcript)|go:"GO:0001669"(acrosomal vesicle)|go:"GO:0002080"(acrosomal membrane)|go:"GO:0005576"(extracellular region)|go:"GO:0005886"(plasma membrane)|go:"GO:0007339"(binding of sperm to zona pellucida)|go:"GO:0009566"(fertilization)|go:"GO:0030317"(flagellated sperm motility)|go:"GO:0044853"(plasma membrane raft)|go:"GO:0046658"(anchored component of plasma membrane)|go:"GO:1901317"(regulation of flagellated sperm motility)|interpro:IPR016054(Ly-6 antigen / uPA receptor -like)|rcsb pdb:7BPR|reactome:R-HSA-163125|refseq:NP_001123483.1|refseq:NP_113639.4 refseq:NP_066964.1|ensembl:ENST00000392132(transcript)|ensembl:ENSG00000079246(gene)|dip:DIP-31379N|go:"GO:0043085"(positive regulation of catalytic activity)|go:"GO:0043564"("Ku70:Ku80 complex")|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045027"(DNA end binding)|go:"GO:0045087"(innate immune response)|go:"GO:0045860"(positive regulation of protein kinase activity)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0048660"(regulation of smooth muscle cell proliferation)|go:"GO:0050769"(positive regulation of neurogenesis)|go:"GO:0051973"(positive regulation of telomerase activity)|go:"GO:0060218"(hematopoietic stem cell differentiation)|go:"GO:0070198"(protein localization to chromosome, telomeric region)|go:"GO:0070419"(nonhomologous end joining complex)|go:"GO:0071398"(cellular response to fatty acid)|go:"GO:0071475"(cellular hyperosmotic salinity response)|go:"GO:0071480"(cellular response to gamma radiation)|go:"GO:0071481"(cellular response to X-ray)|go:"GO:0090734"(site of DNA damage)|go:"GO:0008094"(ATP-dependent activity, acting on DNA)|go:"GO:0008283"(cell population proliferation)|go:"GO:0016020"(membrane)|go:"GO:0016787"(hydrolase activity)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032040"(small-subunit processome)|go:"GO:0032204"(regulation of telomere maintenance)|go:"GO:0032212"(positive regulation of telomere maintenance via telomerase)|go:"GO:0032991"(protein-containing complex)|go:"GO:0032993"(protein-DNA complex)|go:"GO:0034462"(small-subunit processome assembly)|go:"GO:0034511"(U3 snoRNA binding)|go:"GO:0034774"(secretory granule lumen)|go:"GO:0042162"(telomeric DNA binding)|go:"GO:0042493"|ensembl:ENST00000392133(transcript)|go:"GO:0000723"(telomere maintenance)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0000783"(nuclear telomere cap complex)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0002218"(activation of innate immune response)|go:"GO:0003677"(DNA binding)|go:"GO:0003678"(DNA helicase activity)|go:"GO:0003684"(damaged DNA binding)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006302"(double-strand break repair)|go:"GO:0006303"(double-strand break repair via nonhomologous end joining)|go:"GO:0006310"(DNA recombination)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0007420"(brain development)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008047"(enzyme activator activity)|go:"GO:1904430"(negative regulation of t-circle formation)|go:"GO:1990830"(cellular response to leukemia inhibitory factor)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR002035(von Willebrand factor, type A)|interpro:IPR005160(Ku70/Ku80 C-terminal arm)|interpro:IPR005161(Ku70/Ku80, N-terminal alpha/beta)|interpro:IPR006164(DNA helicase, ATP-dependent, Ku type)|interpro:IPR014893(Ku, C-terminal)|interpro:IPR016194(Spen Paralogue and Orthologue C-terminal-like)|interpro:IPR024193|interpro:IPR036465|interpro:IPR036494|mint:P13010|rcsb pdb:1JEQ|rcsb pdb:1JEY|rcsb pdb:1Q2Z|rcsb pdb:1RW2|rcsb pdb:3RZ9|rcsb pdb:5Y3R|rcsb pdb:6ERF|rcsb pdb:6ERG|rcsb pdb:6ERH|rcsb pdb:6ZH6|rcsb pdb:6ZHA|rcsb pdb:6ZHE|rcsb pdb:7AXZ|rcsb pdb:7K0Y|rcsb pdb:7K17|rcsb pdb:7K1J|rcsb pdb:7K1K|rcsb pdb:7K1N|rcsb pdb:7LSY|rcsb pdb:7LT3|reactome:R-HSA-164843|reactome:R-HSA-1834949|reactome:R-HSA-3270619|reactome:R-HSA-5693571|reactome:R-HSA-6798695 - - - figure legend:Supp Table S4 and Supp Fig. S3|comment:"Coimmunoprecipitation with 34ED229 (T2) anti-TEX101 antibody"|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-testis)|taxid:9606(Homo sapiens) - 2020/03/24 2020/06/18 rogid:ZE4tXTFi7lUCcIbCL4KHzY3a6xM9606 rogid:ZPJCWdA2YqOqXgfSRfDQCoEsyoA9606 rigid:2wTqH12DHkSLcixvnxiJPZhqAc0 false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9BY14 uniprotkb:P21796 intact:EBI-12549378|ensembl:ENSP00000472769|uniprotkb:Q7L5R2|uniprotkb:Q9BPY7 intact:EBI-354158|uniprotkb:Q5FVE7|uniprotkb:Q9UIQ5|uniprotkb:Q9UPL0|uniprotkb:B3KVK4|uniprotkb:D3DQ93|ensembl:ENSP00000265333|ensembl:ENSP00000378484|ensembl:ENSP00000378487 psi-mi:tx101_human(display_long)|uniprotkb:TEX101(gene name)|psi-mi:TEX101(display_short)|uniprotkb:Cell surface receptor NYD-SP8(gene name synonym)|uniprotkb:SGRG(gene name synonym)|uniprotkb:Scleroderma-associated autoantigen(gene name synonym)|uniprotkb:Spermatogenesis-related gene protein(gene name synonym)|uniprotkb:UNQ867/PRO1884(orf name) psi-mi:vdac1_human(display_long)|uniprotkb:VDAC1(gene name)|psi-mi:VDAC1(display_short)|uniprotkb:VDAC(gene name synonym)|uniprotkb:Outer mitochondrial membrane protein porin 1(gene name synonym)|uniprotkb:Plasmalemmal porin(gene name synonym)|uniprotkb:Porin 31HL(gene name synonym)|uniprotkb:Porin 31HM(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Schiza et al. (2018) imex:IM-28077|pubmed:30097533 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-25504841|imex:IM-28077-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000131126(gene)|ensembl:ENST00000598265(transcript)|go:"GO:0001669"(acrosomal vesicle)|go:"GO:0002080"(acrosomal membrane)|go:"GO:0005576"(extracellular region)|go:"GO:0005886"(plasma membrane)|go:"GO:0007339"(binding of sperm to zona pellucida)|go:"GO:0009566"(fertilization)|go:"GO:0030317"(flagellated sperm motility)|go:"GO:0044853"(plasma membrane raft)|go:"GO:0046658"(anchored component of plasma membrane)|go:"GO:1901317"(regulation of flagellated sperm motility)|interpro:IPR016054(Ly-6 antigen / uPA receptor -like)|rcsb pdb:7BPR|reactome:R-HSA-163125|refseq:NP_001123483.1|refseq:NP_113639.4 refseq:NP_003365.1|refseq:XP_005272132.1|refseq:XP_016865310.1|refseq:XP_016865311.1|refseq:XP_016865312.1|dip:DIP-32862N|ensembl:ENSG00000213585(gene)|ensembl:ENST00000265333(transcript)|ensembl:ENST00000395044(transcript)|ensembl:ENST00000395047(transcript)|go:"GO:0001662"(behavioral fear response)|go:"GO:0005634"(nucleus)|go:"GO:0005739"(mitochondrion)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005757"(mitochondrial permeability transition pore complex)|go:"GO:0005886"(plasma membrane)|go:"GO:0006090"(pyruvate metabolic process)|go:"GO:0006820"(anion transport)|go:"GO:0006851"(mitochondrial calcium ion transmembrane transport)|go:"GO:0006915"(apoptotic process)|go:"GO:0007270"(neuron-neuron synaptic transmission)|go:"GO:0007612"(learning)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0008308"(voltage-gated anion channel activity)|go:"GO:0015288"(porin activity)|go:"GO:0015485"(cholesterol binding)|go:"GO:0016020"(membrane)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030855"(epithelial cell differentiation)|go:"GO:0031210"(phosphatidylcholine binding)|go:"GO:0031966"(mitochondrial membrane)|go:"GO:0042645"(mitochondrial nucleoid)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045121"(membrane raft)|go:"GO:0046930"(pore complex)|go:"GO:0070062"(extracellular exosome)|go:"GO:0097001"(ceramide binding)|go:"GO:0110099"(negative regulation of calcium import into the mitochondrion)|go:"GO:1901526"(positive regulation of mitophagy)|go:"GO:1903146"(regulation of autophagy of mitochondrion)|go:"GO:2000378"(negative regulation of reactive oxygen species metabolic process)|interpro:IPR001925(Porin, eukaryotic type)|interpro:IPR023614|interpro:IPR027246|interpro:IPR030270|mint:P21796|rcsb pdb:2JK4|rcsb pdb:2K4T|rcsb pdb:5JDP|rcsb pdb:5XDN|rcsb pdb:5XDO|rcsb pdb:6G6U|rcsb pdb:6G73|rcsb pdb:6TIQ|rcsb pdb:6TIR|reactome:R-HSA-1268020|reactome:R-HSA-5205685|reactome:R-HSA-5689880|reactome:R-HSA-70268|reactome:R-HSA-8949215 - - - figure legend:Supp Table S4 and Supp Fig. S3|comment:"Coimmunoprecipitation with 34ED229 (T2) anti-TEX101 antibody"|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-testis)|taxid:9606(Homo sapiens) - 2020/03/24 2020/06/18 rogid:ZE4tXTFi7lUCcIbCL4KHzY3a6xM9606 rogid:8Fqe6Ga3NmwwuICa4L45ga2i1nk9606 rigid:2wTqH12DHkSLcixvnxiJPZhqAc0 false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9BY14 uniprotkb:P11279 intact:EBI-12549378|ensembl:ENSP00000472769|uniprotkb:Q7L5R2|uniprotkb:Q9BPY7 intact:EBI-2805407|uniprotkb:B4DWL3|ensembl:ENSP00000333298|uniprotkb:Q9NP13|uniprotkb:Q8WU33|uniprotkb:Q9BRD2|uniprotkb:Q96I40 psi-mi:tx101_human(display_long)|uniprotkb:TEX101(gene name)|psi-mi:TEX101(display_short)|uniprotkb:Cell surface receptor NYD-SP8(gene name synonym)|uniprotkb:SGRG(gene name synonym)|uniprotkb:Scleroderma-associated autoantigen(gene name synonym)|uniprotkb:Spermatogenesis-related gene protein(gene name synonym)|uniprotkb:UNQ867/PRO1884(orf name) psi-mi:lamp1_human(display_long)|uniprotkb:CD107 antigen-like family member A(gene name synonym)|uniprotkb:LAMP1(gene name)|psi-mi:LAMP1(display_short) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Schiza et al. (2018) imex:IM-28077|pubmed:30097533 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-25504841|imex:IM-28077-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000131126(gene)|ensembl:ENST00000598265(transcript)|go:"GO:0001669"(acrosomal vesicle)|go:"GO:0002080"(acrosomal membrane)|go:"GO:0005576"(extracellular region)|go:"GO:0005886"(plasma membrane)|go:"GO:0007339"(binding of sperm to zona pellucida)|go:"GO:0009566"(fertilization)|go:"GO:0030317"(flagellated sperm motility)|go:"GO:0044853"(plasma membrane raft)|go:"GO:0046658"(anchored component of plasma membrane)|go:"GO:1901317"(regulation of flagellated sperm motility)|interpro:IPR016054(Ly-6 antigen / uPA receptor -like)|rcsb pdb:7BPR|reactome:R-HSA-163125|refseq:NP_001123483.1|refseq:NP_113639.4 ensembl:ENSG00000185896(gene)|go:"GO:0016020"(membrane)|go:"GO:0019899"(enzyme binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030285"(integral component of synaptic vesicle membrane)|go:"GO:0030425"(dendrite)|go:"GO:0031902"(late endosome membrane)|go:"GO:0035577"(azurophil granule membrane)|go:"GO:0042383"(sarcolemma)|go:"GO:0042470"(melanosome)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043323"(positive regulation of natural killer cell degranulation)|go:"GO:0044754"(autolysosome)|go:"GO:0045954"(positive regulation of natural killer cell mediated cytotoxicity)|go:"GO:0048102"(autophagic cell death)|go:"GO:0048471"(perinuclear region of cytoplasm)|ensembl:ENST00000332556(transcript)|go:"GO:0000421"(autophagosome membrane)|go:"GO:0001618"(virus receptor activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005764"(lysosome)|go:"GO:0050821"(protein stabilization)|go:"GO:0061474"(phagolysosome membrane)|go:"GO:0070062"(extracellular exosome)|go:"GO:0072594"(establishment of protein localization to organelle)|go:"GO:0090160"(Golgi to lysosome transport)|go:"GO:0097208"(alveolar lamellar body)|go:"GO:0101003"(ficolin-1-rich granule membrane)|go:"GO:0101004"(cytolytic granule membrane)|go:"GO:0140507"(granzyme-mediated programmed cell death signaling pathway)|go:"GO:1902513"(regulation of organelle transport along microtubule)|interpro:IPR002000("Lysosome-associated membrane glycoprotein (Lamp)/CD68")|interpro:IPR018134|mint:P11279|reactome:R-HSA-6798695|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005770"(late endosome)|go:"GO:0005771"(multivesicular body)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0009897"(external side of plasma membrane)|go:"GO:0010008"(endosome membrane)|refseq:NP_005552.3|dip:DIP-44670N - - - figure legend:Supp Table S4 and Supp Fig. S3|comment:"Coimmunoprecipitation with 34ED229 (T2) anti-TEX101 antibody"|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-testis)|taxid:9606(Homo sapiens) - 2020/03/24 2020/06/18 rogid:ZE4tXTFi7lUCcIbCL4KHzY3a6xM9606 rogid:dP5MZG0I7/SM0EfCUhsESfQYvYU9606 rigid:2wTqH12DHkSLcixvnxiJPZhqAc0 false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9BY14 uniprotkb:Q9UKY0 intact:EBI-12549378|ensembl:ENSP00000472769|uniprotkb:Q7L5R2|uniprotkb:Q9BPY7 intact:EBI-17783836|uniprotkb:A7U7M5|uniprotkb:Q9H311|uniprotkb:Q9H312|uniprotkb:Q9NTM4|ensembl:ENSP00000306900 psi-mi:tx101_human(display_long)|uniprotkb:TEX101(gene name)|psi-mi:TEX101(display_short)|uniprotkb:Cell surface receptor NYD-SP8(gene name synonym)|uniprotkb:SGRG(gene name synonym)|uniprotkb:Scleroderma-associated autoantigen(gene name synonym)|uniprotkb:Spermatogenesis-related gene protein(gene name synonym)|uniprotkb:UNQ867/PRO1884(orf name) psi-mi:prnd_human(display_long)|uniprotkb:PrPLP(gene name synonym)|uniprotkb:Prion protein 2(gene name synonym)|uniprotkb:UNQ1830/PRO3443(orf name)|uniprotkb:PRND(gene name)|psi-mi:PRND(display_short)|uniprotkb:DPL(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Schiza et al. (2018) imex:IM-28077|pubmed:30097533 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-25504841|imex:IM-28077-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000131126(gene)|ensembl:ENST00000598265(transcript)|go:"GO:0001669"(acrosomal vesicle)|go:"GO:0002080"(acrosomal membrane)|go:"GO:0005576"(extracellular region)|go:"GO:0005886"(plasma membrane)|go:"GO:0007339"(binding of sperm to zona pellucida)|go:"GO:0009566"(fertilization)|go:"GO:0030317"(flagellated sperm motility)|go:"GO:0044853"(plasma membrane raft)|go:"GO:0046658"(anchored component of plasma membrane)|go:"GO:1901317"(regulation of flagellated sperm motility)|interpro:IPR016054(Ly-6 antigen / uPA receptor -like)|rcsb pdb:7BPR|reactome:R-HSA-163125|refseq:NP_001123483.1|refseq:NP_113639.4 refseq:NP_036541.2|ensembl:ENSG00000171864(gene)|ensembl:ENST00000305817(transcript)|go:"GO:0005507"(copper ion binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005886"(plasma membrane)|go:"GO:0006878"(cellular copper ion homeostasis)|go:"GO:0007340"(acrosome reaction)|go:"GO:0031362"(anchored component of external side of plasma membrane)|go:"GO:0051260"(protein homooligomerization)|interpro:IPR021566|interpro:IPR022416|interpro:IPR036924|rcsb pdb:1LG4|reactome:R-HSA-163125 - - - figure legend:Supp Table S4 and Supp Fig. S3|comment:"Coimmunoprecipitation with 34ED229 (T2) anti-TEX101 antibody"|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-testis)|taxid:9606(Homo sapiens) - 2020/03/24 2020/06/18 rogid:ZE4tXTFi7lUCcIbCL4KHzY3a6xM9606 rogid:p/L2mClefPuCaexWyimrRBRDdUE9606 rigid:2wTqH12DHkSLcixvnxiJPZhqAc0 false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9BY14 uniprotkb:P46940 intact:EBI-12549378|ensembl:ENSP00000472769|uniprotkb:Q7L5R2|uniprotkb:Q9BPY7 intact:EBI-297509|ensembl:ENSP00000268182|uniprotkb:A7MBM3 psi-mi:tx101_human(display_long)|uniprotkb:TEX101(gene name)|psi-mi:TEX101(display_short)|uniprotkb:Cell surface receptor NYD-SP8(gene name synonym)|uniprotkb:SGRG(gene name synonym)|uniprotkb:Scleroderma-associated autoantigen(gene name synonym)|uniprotkb:Spermatogenesis-related gene protein(gene name synonym)|uniprotkb:UNQ867/PRO1884(orf name) psi-mi:iqga1_human(display_long)|uniprotkb:IQGAP1(gene name)|psi-mi:IQGAP1(display_short)|uniprotkb:KIAA0051(gene name synonym)|uniprotkb:p195(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Schiza et al. (2018) imex:IM-28077|pubmed:30097533 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-25504841|imex:IM-28077-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000131126(gene)|ensembl:ENST00000598265(transcript)|go:"GO:0001669"(acrosomal vesicle)|go:"GO:0002080"(acrosomal membrane)|go:"GO:0005576"(extracellular region)|go:"GO:0005886"(plasma membrane)|go:"GO:0007339"(binding of sperm to zona pellucida)|go:"GO:0009566"(fertilization)|go:"GO:0030317"(flagellated sperm motility)|go:"GO:0044853"(plasma membrane raft)|go:"GO:0046658"(anchored component of plasma membrane)|go:"GO:1901317"(regulation of flagellated sperm motility)|interpro:IPR016054(Ly-6 antigen / uPA receptor -like)|rcsb pdb:7BPR|reactome:R-HSA-163125|refseq:NP_001123483.1|refseq:NP_113639.4 ensembl:ENSG00000140575(gene)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005547"(phosphatidylinositol-3,4,5-trisphosphate binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005874"(microtubule)|go:"GO:0005884"(actin filament)|go:"GO:0005886"(plasma membrane)|ensembl:ENST00000268182(transcript)|go:"GO:0001726"(ruffle)|go:"GO:0005925"(focal adhesion)|go:"GO:0007165"(signal transduction)|go:"GO:0007173"(epidermal growth factor receptor signaling pathway)|go:"GO:0005078"(MAP-kinase scaffold activity)|go:"GO:0005095"(GTPase inhibitor activity)|go:"GO:0007346"(regulation of mitotic cell cycle)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0016477"(cell migration)|go:"GO:0019901"(protein kinase binding)|go:"GO:0019903"(protein phosphatase binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0005509"(calcium ion binding)|go:"GO:0030424"(axon)|go:"GO:0030426"(growth cone)|go:"GO:0030496"(midbody)|go:"GO:0031234"(extrinsic component of cytoplasmic side of plasma membrane)|go:"GO:0031267"(small GTPase binding)|go:"GO:0032956"(regulation of actin cytoskeleton organization)|go:"GO:0032991"(protein-containing complex)|go:"GO:0036057"(slit diaphragm)|go:"GO:0036464"(cytoplasmic ribonucleoprotein granule)|go:"GO:0043005"(neuron projection)|go:"GO:0043087"(regulation of GTPase activity)|go:"GO:0043406"(positive regulation of MAP kinase activity)|go:"GO:0043410"(positive regulation of MAPK cascade)|go:"GO:0043539"(protein serine/threonine kinase activator activity)|go:"GO:0044548"(S100 protein binding)|go:"GO:0045121"(membrane raft)|go:"GO:0045296"(cadherin binding)|go:"GO:0045860"(positive regulation of protein kinase activity)|go:"GO:0051015"(actin filament binding)|go:"GO:0051019"(mitogen-activated protein kinase binding)|go:"GO:0051894"(positive regulation of focal adhesion assembly)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071277"(cellular response to calcium ion)|go:"GO:0071364"(cellular response to epidermal growth factor stimulus)|go:"GO:0072015"(glomerular visceral epithelial cell development)|go:"GO:1900006"(positive regulation of dendrite development)|go:"GO:1900086"(positive regulation of peptidyl-tyrosine autophosphorylation)|go:"GO:1903829"(positive regulation of protein localization)|go:"GO:1904754"(positive regulation of vascular associated smooth muscle cell migration)|go:"GO:1990138"(neuron projection extension)|go:"GO:1990776"(response to angiotensin)|interpro:IPR000048(IQ calmodulin-binding region)|go:"GO:0030667"(secretory granule membrane)|interpro:IPR000593(RasGAP protein, C-terminal)|interpro:IPR001202(WW/Rsp5/WWP)|interpro:IPR001715(Calponin-like actin-binding)|interpro:IPR001936(Ras GTPase-activating protein)|interpro:IPR008936(Rho GTPase activation protein)|interpro:IPR023152|interpro:IPR027417|interpro:IPR036872|mint:P46940|rcsb pdb:1X0H|rcsb pdb:2RR8|rcsb pdb:3FAY|rcsb pdb:3I6X|rcsb pdb:5L0O|reactome:R-HSA-373753|reactome:R-HSA-381676|reactome:R-HSA-5626467|reactome:R-HSA-5674135|reactome:R-HSA-6798695|reactome:R-HSA-6802946|reactome:R-HSA-6802948|reactome:R-HSA-6802952|reactome:R-HSA-6802955|reactome:R-HSA-8980692|reactome:R-HSA-9013106|reactome:R-HSA-9013148|reactome:R-HSA-9013149|reactome:R-HSA-9013404|reactome:R-HSA-9013406|reactome:R-HSA-9013420|reactome:R-HSA-9013424|reactome:R-HSA-9649948|reactome:R-HSA-9656223|refseq:NP_003861.1|dip:DIP-32597N - - - figure legend:Supp Table S4 and Supp Fig. S3|comment:"Coimmunoprecipitation with 34ED229 (T2) anti-TEX101 antibody"|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-testis)|taxid:9606(Homo sapiens) - 2020/03/24 2020/06/18 rogid:ZE4tXTFi7lUCcIbCL4KHzY3a6xM9606 rogid:nXO2Z6Qn8EQGfziT8dnWz1pbK/w9606 rigid:2wTqH12DHkSLcixvnxiJPZhqAc0 false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9BY14 uniprotkb:P06737 intact:EBI-12549378|ensembl:ENSP00000472769|uniprotkb:Q7L5R2|uniprotkb:Q9BPY7 intact:EBI-2511865|ensembl:ENSP00000216392|uniprotkb:O60567|uniprotkb:O60913|uniprotkb:O60752|uniprotkb:A6NDQ4|uniprotkb:Q501V9|uniprotkb:Q96G82|uniprotkb:Q641R5|uniprotkb:B4DUB7|uniprotkb:F5H816 psi-mi:tx101_human(display_long)|uniprotkb:TEX101(gene name)|psi-mi:TEX101(display_short)|uniprotkb:Cell surface receptor NYD-SP8(gene name synonym)|uniprotkb:SGRG(gene name synonym)|uniprotkb:Scleroderma-associated autoantigen(gene name synonym)|uniprotkb:Spermatogenesis-related gene protein(gene name synonym)|uniprotkb:UNQ867/PRO1884(orf name) psi-mi:pygl_human(display_long)|uniprotkb:PYGL(gene name)|psi-mi:PYGL(display_short) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Schiza et al. (2018) imex:IM-28077|pubmed:30097533 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-25504841|imex:IM-28077-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000131126(gene)|ensembl:ENST00000598265(transcript)|go:"GO:0001669"(acrosomal vesicle)|go:"GO:0002080"(acrosomal membrane)|go:"GO:0005576"(extracellular region)|go:"GO:0005886"(plasma membrane)|go:"GO:0007339"(binding of sperm to zona pellucida)|go:"GO:0009566"(fertilization)|go:"GO:0030317"(flagellated sperm motility)|go:"GO:0044853"(plasma membrane raft)|go:"GO:0046658"(anchored component of plasma membrane)|go:"GO:1901317"(regulation of flagellated sperm motility)|interpro:IPR016054(Ly-6 antigen / uPA receptor -like)|rcsb pdb:7BPR|reactome:R-HSA-163125|refseq:NP_001123483.1|refseq:NP_113639.4 ensembl:ENSG00000100504(gene)|ensembl:ENST00000216392(transcript)|go:"GO:0002060"(purine nucleobase binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005536"(glucose binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005977"(glycogen metabolic process)|go:"GO:0005980"(glycogen catabolic process)|go:"GO:0006015"(5-phosphoribose 1-diphosphate biosynthetic process)|go:"GO:0008184"(glycogen phosphorylase activity)|go:"GO:0009617"(response to bacterium)|go:"GO:0016208"(AMP binding)|go:"GO:0019842"(vitamin binding)|go:"GO:0030170"(pyridoxal phosphate binding)|go:"GO:0032052"(bile acid binding)|go:"GO:0034774"(secretory granule lumen)|go:"GO:0042593"(glucose homeostasis)|go:"GO:0042802"(identical protein binding)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070266"(necroptotic process)|go:"GO:0102250"(linear malto-oligosaccharide phosphorylase activity)|go:"GO:0102499"(SHG alpha-glucan phosphorylase activity)|go:"GO:1904813"(ficolin-1-rich granule lumen)|interpro:IPR000811(Glycosyl transferase, family 35)|interpro:IPR011833(Glycogen/starch/alpha-glucan phosphorylase)|interpro:IPR035090|mint:P06737|rcsb pdb:1EM6|rcsb pdb:1EXV|rcsb pdb:1FA9|rcsb pdb:1FC0|rcsb pdb:1L5Q|rcsb pdb:1L5R|rcsb pdb:1L5S|rcsb pdb:1L7X|rcsb pdb:1XOI|rcsb pdb:2ATI|rcsb pdb:2QLL|rcsb pdb:2ZB2|rcsb pdb:3CEH|rcsb pdb:3CEJ|rcsb pdb:3CEM|rcsb pdb:3DD1|rcsb pdb:3DDS|rcsb pdb:3DDW|reactome:R-HSA-70221|reactome:R-HSA-6798695|refseq:NP_001157412.1|refseq:NP_002854.3 - - - figure legend:Supp Table S4 and Supp Fig. S3|comment:"Coimmunoprecipitation with 34ED229 (T2) anti-TEX101 antibody"|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-testis)|taxid:9606(Homo sapiens) - 2020/03/24 2020/06/18 rogid:ZE4tXTFi7lUCcIbCL4KHzY3a6xM9606 rogid:8h3TR7UB7SC/CFh5TXcjHvE/C709606 rigid:2wTqH12DHkSLcixvnxiJPZhqAc0 false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9BY14 uniprotkb:Q9NPH2 intact:EBI-12549378|ensembl:ENSP00000472769|uniprotkb:Q7L5R2|uniprotkb:Q9BPY7 intact:EBI-720563|intact:EBI-1050340|uniprotkb:Q7Z525|uniprotkb:Q9BT65|uniprotkb:Q9H2Y2|uniprotkb:Q9NSU0|uniprotkb:Q9NVW7|uniprotkb:Q6NXT5|uniprotkb:B3KRT1|uniprotkb:G5E9U0|ensembl:ENSP00000337746 psi-mi:tx101_human(display_long)|uniprotkb:TEX101(gene name)|psi-mi:TEX101(display_short)|uniprotkb:Cell surface receptor NYD-SP8(gene name synonym)|uniprotkb:SGRG(gene name synonym)|uniprotkb:Scleroderma-associated autoantigen(gene name synonym)|uniprotkb:Spermatogenesis-related gene protein(gene name synonym)|uniprotkb:UNQ867/PRO1884(orf name) psi-mi:ino1_human(display_long)|uniprotkb:INO1(gene name synonym)|uniprotkb:ISYNA1(gene name)|psi-mi:ISYNA1(display_short)|uniprotkb:Myo-inositol 1-phosphate synthase A1(gene name synonym)|uniprotkb:Myo-inositol 1-phosphate synthase(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Schiza et al. (2018) imex:IM-28077|pubmed:30097533 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-25504841|imex:IM-28077-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000131126(gene)|ensembl:ENST00000598265(transcript)|go:"GO:0001669"(acrosomal vesicle)|go:"GO:0002080"(acrosomal membrane)|go:"GO:0005576"(extracellular region)|go:"GO:0005886"(plasma membrane)|go:"GO:0007339"(binding of sperm to zona pellucida)|go:"GO:0009566"(fertilization)|go:"GO:0030317"(flagellated sperm motility)|go:"GO:0044853"(plasma membrane raft)|go:"GO:0046658"(anchored component of plasma membrane)|go:"GO:1901317"(regulation of flagellated sperm motility)|interpro:IPR016054(Ly-6 antigen / uPA receptor -like)|rcsb pdb:7BPR|reactome:R-HSA-163125|refseq:NP_001123483.1|refseq:NP_113639.4 refseq:NP_001164409.1|refseq:NP_057452.1|refseq:NP_001240318.1|go:"GO:0006021"(inositol biosynthetic process)|go:"GO:0008654"(phospholipid biosynthetic process)|interpro:IPR002587(Myo-inositol-1-phosphate synthase)|interpro:IPR013021(Myo-inositol-1-phosphate synthase, GAPDH-like)|interpro:IPR036291|reactome:R-HSA-1855183|ensembl:ENSG00000105655(gene)|ensembl:ENST00000338128(transcript)|go:"GO:0004512"(inositol-3-phosphate synthase activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol) - - - figure legend:Supp Table S4 and Supp Fig. S3|comment:"Coimmunoprecipitation with 34ED229 (T2) anti-TEX101 antibody"|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-testis)|taxid:9606(Homo sapiens) - 2020/03/24 2020/06/18 rogid:ZE4tXTFi7lUCcIbCL4KHzY3a6xM9606 rogid:46Ryo/iaI6hmbkuetMsJSyrm3FU9606 rigid:2wTqH12DHkSLcixvnxiJPZhqAc0 false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9BY14 uniprotkb:Q9Y6G9 intact:EBI-12549378|ensembl:ENSP00000472769|uniprotkb:Q7L5R2|uniprotkb:Q9BPY7 intact:EBI-2556107|uniprotkb:A2RRG7|uniprotkb:Q53HK7|uniprotkb:Q53HC8|ensembl:ENSP00000273130 psi-mi:tx101_human(display_long)|uniprotkb:TEX101(gene name)|psi-mi:TEX101(display_short)|uniprotkb:Cell surface receptor NYD-SP8(gene name synonym)|uniprotkb:SGRG(gene name synonym)|uniprotkb:Scleroderma-associated autoantigen(gene name synonym)|uniprotkb:Spermatogenesis-related gene protein(gene name synonym)|uniprotkb:UNQ867/PRO1884(orf name) psi-mi:dc1l1_human(display_long)|uniprotkb:DNCLI1(gene name synonym)|uniprotkb:Dynein light intermediate chain 1, cytosolic(gene name synonym)|uniprotkb:Dynein light chain A(gene name synonym)|uniprotkb:DYNC1LI1(gene name)|psi-mi:DYNC1LI1(display_short) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Schiza et al. (2018) imex:IM-28077|pubmed:30097533 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-25504841|imex:IM-28077-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000131126(gene)|ensembl:ENST00000598265(transcript)|go:"GO:0001669"(acrosomal vesicle)|go:"GO:0002080"(acrosomal membrane)|go:"GO:0005576"(extracellular region)|go:"GO:0005886"(plasma membrane)|go:"GO:0007339"(binding of sperm to zona pellucida)|go:"GO:0009566"(fertilization)|go:"GO:0030317"(flagellated sperm motility)|go:"GO:0044853"(plasma membrane raft)|go:"GO:0046658"(anchored component of plasma membrane)|go:"GO:1901317"(regulation of flagellated sperm motility)|interpro:IPR016054(Ly-6 antigen / uPA receptor -like)|rcsb pdb:7BPR|reactome:R-HSA-163125|refseq:NP_001123483.1|refseq:NP_113639.4 refseq:NP_057225.2|ensembl:ENSG00000144635(gene)|ensembl:ENST00000273130(transcript)|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0000776"(kinetochore)|go:"GO:0000922"(spindle pole)|go:"GO:0003723"(RNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005868"(cytoplasmic dynein complex)|go:"GO:0005874"(microtubule)|go:"GO:0005886"(plasma membrane)|go:"GO:0007049"(cell cycle)|go:"GO:0016020"(membrane)|go:"GO:0019003"(GDP binding)|go:"GO:0030667"(secretory granule membrane)|go:"GO:0045504"(dynein heavy chain binding)|go:"GO:0051301"(cell division)|go:"GO:0090267"(positive regulation of mitotic cell cycle spindle assembly checkpoint)|go:"GO:0101003"(ficolin-1-rich granule membrane)|interpro:IPR008467(Dynein light intermediate chain)|interpro:IPR022780|interpro:IPR027417|mint:Q9Y6G9|rcsb pdb:6B9H|rcsb pdb:6PSD|rcsb pdb:6PSE|reactome:R-HSA-141444|reactome:R-HSA-2132295|reactome:R-HSA-2467813|reactome:R-HSA-2500257|reactome:R-HSA-3371497|reactome:R-HSA-5663220|reactome:R-HSA-6798695|reactome:R-HSA-6807878|reactome:R-HSA-6811436|reactome:R-HSA-68877|reactome:R-HSA-9609690|reactome:R-HSA-9646399|reactome:R-HSA-9648025|go:"GO:0007018"(microtubule-based movement) - - - figure legend:Supp Table S4 and Supp Fig. S3|comment:"Coimmunoprecipitation with 34ED229 (T2) anti-TEX101 antibody"|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-testis)|taxid:9606(Homo sapiens) - 2020/03/24 2020/06/18 rogid:ZE4tXTFi7lUCcIbCL4KHzY3a6xM9606 rogid:LxQSfBpzuf6Acus2jBy0s53FdhU9606 rigid:2wTqH12DHkSLcixvnxiJPZhqAc0 false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9BY14 uniprotkb:Q13619 intact:EBI-12549378|ensembl:ENSP00000472769|uniprotkb:Q7L5R2|uniprotkb:Q9BPY7 intact:EBI-456106|uniprotkb:O75834|uniprotkb:Q589T6|uniprotkb:Q5TC62|uniprotkb:Q6UP08|uniprotkb:Q9UP17|uniprotkb:A2A2W2|ensembl:ENSP00000364589 psi-mi:tx101_human(display_long)|uniprotkb:TEX101(gene name)|psi-mi:TEX101(display_short)|uniprotkb:Cell surface receptor NYD-SP8(gene name synonym)|uniprotkb:SGRG(gene name synonym)|uniprotkb:Scleroderma-associated autoantigen(gene name synonym)|uniprotkb:Spermatogenesis-related gene protein(gene name synonym)|uniprotkb:UNQ867/PRO1884(orf name) psi-mi:cul4a_human(display_long)|uniprotkb:CUL4A(gene name)|psi-mi:CUL4A(display_short) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Schiza et al. (2018) imex:IM-28077|pubmed:30097533 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-25504841|imex:IM-28077-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000131126(gene)|ensembl:ENST00000598265(transcript)|go:"GO:0001669"(acrosomal vesicle)|go:"GO:0002080"(acrosomal membrane)|go:"GO:0005576"(extracellular region)|go:"GO:0005886"(plasma membrane)|go:"GO:0007339"(binding of sperm to zona pellucida)|go:"GO:0009566"(fertilization)|go:"GO:0030317"(flagellated sperm motility)|go:"GO:0044853"(plasma membrane raft)|go:"GO:0046658"(anchored component of plasma membrane)|go:"GO:1901317"(regulation of flagellated sperm motility)|interpro:IPR016054(Ly-6 antigen / uPA receptor -like)|rcsb pdb:7BPR|reactome:R-HSA-163125|refseq:NP_001123483.1|refseq:NP_113639.4 refseq:NP_001008895.1|refseq:NP_003580.1|refseq:NP_001265442.1|refseq:XP_011535825.1|dip:DIP-31610N|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0035019"(somatic stem cell population maintenance)|go:"GO:0042254"(ribosome biogenesis)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0048511"(rhythmic process)|go:"GO:0051246"(regulation of protein metabolic process)|go:"GO:0080008"(Cul4-RING E3 ubiquitin ligase complex)|go:"GO:0097193"(intrinsic apoptotic signaling pathway)|go:"GO:1900087"(positive regulation of G1/S transition of mitotic cell cycle)|go:"GO:2000001"(regulation of DNA damage checkpoint)|go:"GO:2000819"(regulation of nucleotide-excision repair)|interpro:IPR001373(Cullin, N-terminal region)|interpro:IPR016157(Cullin, conserved site)|interpro:IPR016158(Cullin homology)|interpro:IPR016159(Cullin repeat-like)|interpro:IPR019559|interpro:IPR036317|interpro:IPR036388|interpro:IPR036390|mint:Q13619|rcsb pdb:2HYE|rcsb pdb:4A0K|reactome:R-HSA-110314|reactome:R-HSA-5696394|reactome:R-HSA-5696395|reactome:R-HSA-5696400|reactome:R-HSA-6781823|reactome:R-HSA-6781827|reactome:R-HSA-6782135|reactome:R-HSA-6782210|reactome:R-HSA-8951664|ensembl:ENSG00000139842(gene)|ensembl:ENST00000375440(transcript)|go:"GO:0000082"(G1/S transition of mitotic cell cycle)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006281"(DNA repair)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0019005"(SCF ubiquitin ligase complex)|go:"GO:0030097"(hemopoiesis)|go:"GO:0030853"(negative regulation of granulocyte differentiation)|go:"GO:0031146"(SCF-dependent proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0031461"(cullin-RING ubiquitin ligase complex)|go:"GO:0031464"(Cul4A-RING E3 ubiquitin ligase complex) - - - figure legend:Supp Table S4 and Supp Fig. S3|comment:"Coimmunoprecipitation with 34ED229 (T2) anti-TEX101 antibody"|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-testis)|taxid:9606(Homo sapiens) - 2020/03/24 2020/06/18 rogid:ZE4tXTFi7lUCcIbCL4KHzY3a6xM9606 rogid:xYRRxjpO/9qqeXtq9dfACAdqyM89606 rigid:2wTqH12DHkSLcixvnxiJPZhqAc0 false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9BY14 uniprotkb:P84074 intact:EBI-12549378|ensembl:ENSP00000472769|uniprotkb:Q7L5R2|uniprotkb:Q9BPY7 intact:EBI-12197079|ensembl:ENSP00000362566|uniprotkb:B2R9T3|uniprotkb:D3DPQ7|uniprotkb:P32076|uniprotkb:P41211|uniprotkb:P70510 psi-mi:tx101_human(display_long)|uniprotkb:TEX101(gene name)|psi-mi:TEX101(display_short)|uniprotkb:Cell surface receptor NYD-SP8(gene name synonym)|uniprotkb:SGRG(gene name synonym)|uniprotkb:Scleroderma-associated autoantigen(gene name synonym)|uniprotkb:Spermatogenesis-related gene protein(gene name synonym)|uniprotkb:UNQ867/PRO1884(orf name) psi-mi:hpca_human(display_long)|uniprotkb:HPCA(gene name)|psi-mi:HPCA(display_short)|uniprotkb:BDR2(gene name synonym)|uniprotkb:Calcium-binding protein BDR-2(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Schiza et al. (2018) imex:IM-28077|pubmed:30097533 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-25504841|imex:IM-28077-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000131126(gene)|ensembl:ENST00000598265(transcript)|go:"GO:0001669"(acrosomal vesicle)|go:"GO:0002080"(acrosomal membrane)|go:"GO:0005576"(extracellular region)|go:"GO:0005886"(plasma membrane)|go:"GO:0007339"(binding of sperm to zona pellucida)|go:"GO:0009566"(fertilization)|go:"GO:0030317"(flagellated sperm motility)|go:"GO:0044853"(plasma membrane raft)|go:"GO:0046658"(anchored component of plasma membrane)|go:"GO:1901317"(regulation of flagellated sperm motility)|interpro:IPR016054(Ly-6 antigen / uPA receptor -like)|rcsb pdb:7BPR|reactome:R-HSA-163125|refseq:NP_001123483.1|refseq:NP_113639.4 ensembl:ENSG00000121905(gene)|ensembl:ENST00000373467(transcript)|go:"GO:0003779"(actin binding)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0007420"(brain development)|go:"GO:0019722"(calcium-mediated signaling)|go:"GO:0019898"(extrinsic component of membrane)|go:"GO:0019900"(kinase binding)|go:"GO:0030424"(axon)|go:"GO:0031283"(negative regulation of guanylate cyclase activity)|go:"GO:0031584"(activation of phospholipase D activity)|go:"GO:0032590"(dendrite membrane)|go:"GO:0032809"(neuronal cell body membrane)|go:"GO:0032839"(dendrite cytoplasm)|go:"GO:0042802"(identical protein binding)|go:"GO:0043204"(perikaryon)|go:"GO:0044327"(dendritic spine head)|go:"GO:0045762"(positive regulation of adenylate cyclase activity)|go:"GO:0048839"(inner ear development)|go:"GO:0060041"(retina development in camera-type eye)|go:"GO:0071257"(cellular response to electrical stimulus)|go:"GO:0071277"(cellular response to calcium ion)|go:"GO:0090314"(positive regulation of protein targeting to membrane)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099149"(regulation of postsynaptic neurotransmitter receptor internalization)|go:"GO:1901385"(regulation of voltage-gated calcium channel activity)|go:"GO:1901986"(response to ketamine)|go:"GO:1902065"(response to L-glutamate)|go:"GO:1904009"(cellular response to monosodium glutamate)|go:"GO:1904010"(response to Aroclor 1254)|interpro:IPR002048(Calcium-binding EF-hand)|interpro:IPR011992(EF-Hand type)|interpro:IPR018247|interpro:IPR028846|rcsb pdb:5G4P|rcsb pdb:5G58|rcsb pdb:5M6C|refseq:NP_002134.2|refseq:XP_005270849.1|refseq:XP_016856607.1 - - - figure legend:Supp Table S4 and Supp Fig. S3|comment:"Coimmunoprecipitation with 34ED229 (T2) anti-TEX101 antibody"|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-testis)|taxid:9606(Homo sapiens) - 2020/03/24 2020/06/18 rogid:ZE4tXTFi7lUCcIbCL4KHzY3a6xM9606 rogid:uqRvTKlr8zMg7+UAfYCSqOljrFc9606 rigid:2wTqH12DHkSLcixvnxiJPZhqAc0 false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9BY14 uniprotkb:P13473 intact:EBI-12549378|ensembl:ENSP00000472769|uniprotkb:Q7L5R2|uniprotkb:Q9BPY7 intact:EBI-2907154|uniprotkb:A8K4X5|uniprotkb:Q16641|uniprotkb:Q96J30|uniprotkb:Q99534|uniprotkb:Q9UD93|uniprotkb:D3DTF0|intact:EBI-4324646|uniprotkb:Q6Q3G8|ensembl:ENSP00000200639 psi-mi:tx101_human(display_long)|uniprotkb:TEX101(gene name)|psi-mi:TEX101(display_short)|uniprotkb:Cell surface receptor NYD-SP8(gene name synonym)|uniprotkb:SGRG(gene name synonym)|uniprotkb:Scleroderma-associated autoantigen(gene name synonym)|uniprotkb:Spermatogenesis-related gene protein(gene name synonym)|uniprotkb:UNQ867/PRO1884(orf name) psi-mi:lamp2_human(display_long)|uniprotkb:LAMP2(gene name)|psi-mi:LAMP2(display_short)|uniprotkb:CD107 antigen-like family member B(gene name synonym)|uniprotkb:LGP-96(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Schiza et al. (2018) imex:IM-28077|pubmed:30097533 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-25504841|imex:IM-28077-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000131126(gene)|ensembl:ENST00000598265(transcript)|go:"GO:0001669"(acrosomal vesicle)|go:"GO:0002080"(acrosomal membrane)|go:"GO:0005576"(extracellular region)|go:"GO:0005886"(plasma membrane)|go:"GO:0007339"(binding of sperm to zona pellucida)|go:"GO:0009566"(fertilization)|go:"GO:0030317"(flagellated sperm motility)|go:"GO:0044853"(plasma membrane raft)|go:"GO:0046658"(anchored component of plasma membrane)|go:"GO:1901317"(regulation of flagellated sperm motility)|interpro:IPR016054(Ly-6 antigen / uPA receptor -like)|rcsb pdb:7BPR|reactome:R-HSA-163125|refseq:NP_001123483.1|refseq:NP_113639.4 refseq:NP_002285.1|refseq:NP_054701.1|refseq:NP_001116078.1|ensembl:ENSG00000005893(gene)|ensembl:ENST00000200639(transcript)|go:"GO:0005615"(extracellular space)|go:"GO:0005764"(lysosome)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005770"(late endosome)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0005886"(plasma membrane)|go:"GO:0006605"(protein targeting)|go:"GO:0009267"(cellular response to starvation)|go:"GO:0016020"(membrane)|go:"GO:0017038"(protein import)|go:"GO:0019899"(enzyme binding)|go:"GO:0031088"(platelet dense granule membrane)|go:"GO:0031333"(negative regulation of protein-containing complex assembly)|go:"GO:0031647"(regulation of protein stability)|go:"GO:0031902"(late endosome membrane)|go:"GO:0035577"(azurophil granule membrane)|go:"GO:0043202"(lysosomal lumen)|go:"GO:0044754"(autolysosome)|go:"GO:0045121"(membrane raft)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0050821"(protein stabilization)|go:"GO:0061684"(chaperone-mediated autophagy)|go:"GO:0061740"(protein targeting to lysosome involved in chaperone-mediated autophagy)|go:"GO:0061742"(chaperone-mediated autophagy translocation complex)|go:"GO:0070062"(extracellular exosome)|go:"GO:0072594"(establishment of protein localization to organelle)|go:"GO:0097352"(autophagosome maturation)|go:"GO:0097637"(integral component of autophagosome membrane)|go:"GO:0101003"(ficolin-1-rich granule membrane)|go:"GO:1905146"(lysosomal protein catabolic process)|go:"GO:1990836"(lysosomal matrix)|interpro:IPR002000("Lysosome-associated membrane glycoprotein (Lamp)/CD68")|interpro:IPR018134|mint:P13473|rcsb pdb:2MOF|rcsb pdb:2MOM|reactome:R-HSA-114608|reactome:R-HSA-6798695|reactome:R-HSA-9613829 - - - figure legend:Supp Table S4 and Supp Fig. S3|comment:"Coimmunoprecipitation with 34ED229 (T2) anti-TEX101 antibody"|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-testis)|taxid:9606(Homo sapiens) - 2020/03/24 2020/06/18 rogid:ZE4tXTFi7lUCcIbCL4KHzY3a6xM9606 rogid:+s4K/qoL3PBwjATJmFDQtqcl/ZQ9606 rigid:2wTqH12DHkSLcixvnxiJPZhqAc0 false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9BY14 uniprotkb:P13987 intact:EBI-12549378|ensembl:ENSP00000472769|uniprotkb:Q7L5R2|uniprotkb:Q9BPY7 intact:EBI-297972|ensembl:ENSP00000340210|ensembl:ENSP00000379191|ensembl:ENSP00000403511|ensembl:ENSP00000404822|ensembl:ENSP00000410182|ensembl:ENSP00000432942|ensembl:ENSP00000494884|ensembl:ENSP00000498448|ensembl:ENSP00000498879|uniprotkb:E9PR17 psi-mi:tx101_human(display_long)|uniprotkb:TEX101(gene name)|psi-mi:TEX101(display_short)|uniprotkb:Cell surface receptor NYD-SP8(gene name synonym)|uniprotkb:SGRG(gene name synonym)|uniprotkb:Scleroderma-associated autoantigen(gene name synonym)|uniprotkb:Spermatogenesis-related gene protein(gene name synonym)|uniprotkb:UNQ867/PRO1884(orf name) psi-mi:cd59_human(display_long)|uniprotkb:CD59(gene name)|psi-mi:CD59(display_short)|uniprotkb:Membrane attack complex inhibition factor(gene name synonym)|uniprotkb:MAC-inhibitory protein(gene name synonym)|uniprotkb:Protectin(gene name synonym)|uniprotkb:MEM43 antigen(gene name synonym)|uniprotkb:Membrane inhibitor of reactive lysis(gene name synonym)|uniprotkb:20 kDa homologous restriction factor(gene name synonym)|uniprotkb:1F5 antigen(gene name synonym)|uniprotkb:MIC11(gene name synonym)|uniprotkb:MIN1(gene name synonym)|uniprotkb:MIN2(gene name synonym)|uniprotkb:MIN3(gene name synonym)|uniprotkb:MSK21(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Schiza et al. (2018) imex:IM-28077|pubmed:30097533 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-25504841|imex:IM-28077-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000131126(gene)|ensembl:ENST00000598265(transcript)|go:"GO:0001669"(acrosomal vesicle)|go:"GO:0002080"(acrosomal membrane)|go:"GO:0005576"(extracellular region)|go:"GO:0005886"(plasma membrane)|go:"GO:0007339"(binding of sperm to zona pellucida)|go:"GO:0009566"(fertilization)|go:"GO:0030317"(flagellated sperm motility)|go:"GO:0044853"(plasma membrane raft)|go:"GO:0046658"(anchored component of plasma membrane)|go:"GO:1901317"(regulation of flagellated sperm motility)|interpro:IPR016054(Ly-6 antigen / uPA receptor -like)|rcsb pdb:7BPR|reactome:R-HSA-163125|refseq:NP_001123483.1|refseq:NP_113639.4 refseq:NP_000602.1|refseq:NP_001120695.1|refseq:NP_001120697.1|refseq:NP_001120698.1|refseq:NP_001120699.1|refseq:NP_976074.1|refseq:NP_976075.1|refseq:NP_976076.1|ensembl:ENST00000395850(transcript)|ensembl:ENST00000415002(transcript)|ensembl:ENST00000437761(transcript)|ensembl:ENST00000445143(transcript)|ensembl:ENST00000527577(transcript)|ensembl:ENST00000642928(transcript)|ensembl:ENST00000651785(transcript)|ensembl:ENST00000652678(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001848"(complement binding)|go:"GO:0001971"(negative regulation of activation of membrane attack complex)|go:"GO:0005615"(extracellular space)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005886"(plasma membrane)|go:"GO:0005925"(focal adhesion)|go:"GO:0007166"(cell surface receptor signaling pathway)|go:"GO:0007596"(blood coagulation)|go:"GO:0009986"(cell surface)|go:"GO:0012507"(ER to Golgi transport vesicle membrane)|go:"GO:0016020"(membrane)|go:"GO:0030133"(transport vesicle)|go:"GO:0030449"(regulation of complement activation)|go:"GO:0031362"(anchored component of external side of plasma membrane)|go:"GO:0031982"(vesicle)|go:"GO:0033116"(endoplasmic reticulum-Golgi intermediate compartment membrane)|go:"GO:0035579"(specific granule membrane)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070821"(tertiary granule membrane)|go:"GO:1903659"(regulation of complement-dependent cytotoxicity)|interpro:IPR016054(Ly-6 antigen / uPA receptor -like)|interpro:IPR018363|interpro:IPR027101|mint:P13987|rcsb pdb:1CDQ|rcsb pdb:1CDR|rcsb pdb:1CDS|rcsb pdb:1ERG|rcsb pdb:1ERH|rcsb pdb:2J8B|rcsb pdb:2OFS|rcsb pdb:2UWR|rcsb pdb:2UX2|rcsb pdb:4BIK|rcsb pdb:5IMT|rcsb pdb:5IMY|rcsb pdb:6ZD0|reactome:R-HSA-204005|reactome:R-HSA-5694530|reactome:R-HSA-6798695|reactome:R-HSA-6807878|reactome:R-HSA-977606|ensembl:ENSG00000085063(gene)|ensembl:ENST00000351554(transcript) - - - figure legend:Supp Table S4 and Supp Fig. S3|comment:"Coimmunoprecipitation with 34ED229 (T2) anti-TEX101 antibody"|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-testis)|taxid:9606(Homo sapiens) - 2020/03/24 2020/06/18 rogid:ZE4tXTFi7lUCcIbCL4KHzY3a6xM9606 rogid:l93Yw04Ax0xODyPzjFqaaMvqBeM9606 rigid:2wTqH12DHkSLcixvnxiJPZhqAc0 false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9BY14 uniprotkb:Q9HB40 intact:EBI-12549378|ensembl:ENSP00000472769|uniprotkb:Q7L5R2|uniprotkb:Q9BPY7 intact:EBI-13943440|uniprotkb:Q96A94|uniprotkb:Q9H3F0|ensembl:ENSP00000262288 psi-mi:tx101_human(display_long)|uniprotkb:TEX101(gene name)|psi-mi:TEX101(display_short)|uniprotkb:Cell surface receptor NYD-SP8(gene name synonym)|uniprotkb:SGRG(gene name synonym)|uniprotkb:Scleroderma-associated autoantigen(gene name synonym)|uniprotkb:Spermatogenesis-related gene protein(gene name synonym)|uniprotkb:UNQ867/PRO1884(orf name) psi-mi:risc_human(display_long)|uniprotkb:SCPEP1(gene name)|psi-mi:SCPEP1(display_short)|uniprotkb:RISC(gene name synonym)|uniprotkb:SCP1(gene name synonym)|uniprotkb:Serine carboxypeptidase 1(gene name synonym)|uniprotkb:MSTP034(orf name)|uniprotkb:UNQ265/PRO302(orf name) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Schiza et al. (2018) imex:IM-28077|pubmed:30097533 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-25504841|imex:IM-28077-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000131126(gene)|ensembl:ENST00000598265(transcript)|go:"GO:0001669"(acrosomal vesicle)|go:"GO:0002080"(acrosomal membrane)|go:"GO:0005576"(extracellular region)|go:"GO:0005886"(plasma membrane)|go:"GO:0007339"(binding of sperm to zona pellucida)|go:"GO:0009566"(fertilization)|go:"GO:0030317"(flagellated sperm motility)|go:"GO:0044853"(plasma membrane raft)|go:"GO:0046658"(anchored component of plasma membrane)|go:"GO:1901317"(regulation of flagellated sperm motility)|interpro:IPR016054(Ly-6 antigen / uPA receptor -like)|rcsb pdb:7BPR|reactome:R-HSA-163125|refseq:NP_001123483.1|refseq:NP_113639.4 refseq:NP_067639.1|ensembl:ENSG00000121064(gene)|ensembl:ENST00000262288(transcript)|go:"GO:0004185"(serine-type carboxypeptidase activity)|go:"GO:0005829"(cytosol)|go:"GO:0042573"(retinoic acid metabolic process)|go:"GO:0045776"(negative regulation of blood pressure)|go:"GO:0070062"(extracellular exosome)|go:"GO:0097746"(blood vessel diameter maintenance)|interpro:IPR001563(Peptidase S10, serine carboxypeptidase)|interpro:IPR018202|interpro:IPR029058 - - - figure legend:Supp Table S4 and Supp Fig. S3|comment:"Coimmunoprecipitation with 34ED229 (T2) anti-TEX101 antibody"|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-testis)|taxid:9606(Homo sapiens) - 2020/03/24 2020/06/18 rogid:ZE4tXTFi7lUCcIbCL4KHzY3a6xM9606 rogid:FMuffJ/BPZAqjTvAjmwOPNQjWrY9606 rigid:2wTqH12DHkSLcixvnxiJPZhqAc0 false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9BY14 uniprotkb:P20340 intact:EBI-12549378|ensembl:ENSP00000472769|uniprotkb:Q7L5R2|uniprotkb:Q9BPY7 intact:EBI-1052826|uniprotkb:Q5U0A8|uniprotkb:Q9UBE4|uniprotkb:A8K133|uniprotkb:Q1W5D8|uniprotkb:B7Z772|uniprotkb:F5H668|ensembl:ENSP00000336850 psi-mi:tx101_human(display_long)|uniprotkb:TEX101(gene name)|psi-mi:TEX101(display_short)|uniprotkb:Cell surface receptor NYD-SP8(gene name synonym)|uniprotkb:SGRG(gene name synonym)|uniprotkb:Scleroderma-associated autoantigen(gene name synonym)|uniprotkb:Spermatogenesis-related gene protein(gene name synonym)|uniprotkb:UNQ867/PRO1884(orf name) psi-mi:rab6a_human(display_long)|uniprotkb:RAB6A(gene name)|psi-mi:RAB6A(display_short)|uniprotkb:RAB6(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Schiza et al. (2018) imex:IM-28077|pubmed:30097533 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-25504841|imex:IM-28077-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000131126(gene)|ensembl:ENST00000598265(transcript)|go:"GO:0001669"(acrosomal vesicle)|go:"GO:0002080"(acrosomal membrane)|go:"GO:0005576"(extracellular region)|go:"GO:0005886"(plasma membrane)|go:"GO:0007339"(binding of sperm to zona pellucida)|go:"GO:0009566"(fertilization)|go:"GO:0030317"(flagellated sperm motility)|go:"GO:0044853"(plasma membrane raft)|go:"GO:0046658"(anchored component of plasma membrane)|go:"GO:1901317"(regulation of flagellated sperm motility)|interpro:IPR016054(Ly-6 antigen / uPA receptor -like)|rcsb pdb:7BPR|reactome:R-HSA-163125|refseq:NP_001123483.1|refseq:NP_113639.4 refseq:NP_002860.2|refseq:NP_942599.1|refseq:NP_001230648.1|refseq:NP_001230647.1|ensembl:ENSG00000175582(gene)|ensembl:ENST00000336083(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006890"(retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum)|go:"GO:0006891"(intra-Golgi vesicle-mediated transport)|go:"GO:0012505"(endomembrane system)|go:"GO:0016020"(membrane)|go:"GO:0018125"(peptidyl-cysteine methylation)|go:"GO:0019882"(antigen processing and presentation)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030667"(secretory granule membrane)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0031489"(myosin V binding)|go:"GO:0032588"(trans-Golgi network membrane)|go:"GO:0034067"(protein localization to Golgi apparatus)|go:"GO:0042147"(retrograde transport, endosome to Golgi)|go:"GO:0034498"(early endosome to Golgi transport)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070381"(endosome to plasma membrane transport vesicle)|go:"GO:0072385"(minus-end-directed organelle transport along microtubule)|interpro:IPR001806(Ras GTPase)|interpro:IPR005225(Small GTP-binding protein)|interpro:IPR027417|mint:P20340|rcsb pdb:1YZQ|rcsb pdb:2GIL|rcsb pdb:3BBP|rcsb pdb:3CWZ|rcsb pdb:4DKX|rcsb pdb:5LEF|reactome:R-HSA-1912420|reactome:R-HSA-6798695|reactome:R-HSA-6811436|reactome:R-HSA-6811440|reactome:R-HSA-8854214|reactome:R-HSA-8873719|reactome:R-HSA-8876198|dip:DIP-39668N - - - figure legend:Supp Table S4 and Supp Fig. S3|comment:"Coimmunoprecipitation with 34ED229 (T2) anti-TEX101 antibody"|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-testis)|taxid:9606(Homo sapiens) - 2020/03/24 2020/06/18 rogid:ZE4tXTFi7lUCcIbCL4KHzY3a6xM9606 rogid:VtLF/2T3LuVttzSCftP/mnAxyLk9606 rigid:2wTqH12DHkSLcixvnxiJPZhqAc0 false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9BY14 uniprotkb:Q92973 intact:EBI-12549378|ensembl:ENSP00000472769|uniprotkb:Q7L5R2|uniprotkb:Q9BPY7 intact:EBI-286693|intact:EBI-1760498|uniprotkb:Q92957|uniprotkb:Q92975|intact:EBI-1965561|uniprotkb:B4DVC6|ensembl:ENSP00000336712 psi-mi:tx101_human(display_long)|uniprotkb:TEX101(gene name)|psi-mi:TEX101(display_short)|uniprotkb:Cell surface receptor NYD-SP8(gene name synonym)|uniprotkb:SGRG(gene name synonym)|uniprotkb:Scleroderma-associated autoantigen(gene name synonym)|uniprotkb:Spermatogenesis-related gene protein(gene name synonym)|uniprotkb:UNQ867/PRO1884(orf name) psi-mi:tnpo1_human(display_long)|uniprotkb:TRN(gene name synonym)|uniprotkb:TNPO1(gene name)|psi-mi:TNPO1(display_short)|uniprotkb:KPNB2(gene name synonym)|uniprotkb:MIP1(gene name synonym)|uniprotkb:Importin beta-2(gene name synonym)|uniprotkb:Karyopherin beta-2(gene name synonym)|uniprotkb:M9 region interaction protein(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Schiza et al. (2018) imex:IM-28077|pubmed:30097533 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-25504841|imex:IM-28077-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000131126(gene)|ensembl:ENST00000598265(transcript)|go:"GO:0001669"(acrosomal vesicle)|go:"GO:0002080"(acrosomal membrane)|go:"GO:0005576"(extracellular region)|go:"GO:0005886"(plasma membrane)|go:"GO:0007339"(binding of sperm to zona pellucida)|go:"GO:0009566"(fertilization)|go:"GO:0030317"(flagellated sperm motility)|go:"GO:0044853"(plasma membrane raft)|go:"GO:0046658"(anchored component of plasma membrane)|go:"GO:1901317"(regulation of flagellated sperm motility)|interpro:IPR016054(Ly-6 antigen / uPA receptor -like)|rcsb pdb:7BPR|reactome:R-HSA-163125|refseq:NP_001123483.1|refseq:NP_113639.4 refseq:NP_002261.3|refseq:NP_694858.1|refseq:XP_005248557.1|dip:DIP-29335N|ensembl:ENSG00000083312(gene)|ensembl:ENST00000337273(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005929"(cilium)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0008139"(nuclear localization sequence binding)|go:"GO:0031267"(small GTPase binding)|go:"GO:0061608"(nuclear import signal receptor activity)|go:"GO:0070062"(extracellular exosome)|interpro:IPR001494(Importin-beta, N-terminal)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR040122|mint:Q92973|rcsb pdb:1QBK|rcsb pdb:2H4M|rcsb pdb:2OT8|rcsb pdb:2QMR|rcsb pdb:2Z5J|rcsb pdb:2Z5K|rcsb pdb:2Z5M|rcsb pdb:2Z5N|rcsb pdb:2Z5O|rcsb pdb:4FDD|rcsb pdb:4FQ3|rcsb pdb:4JLQ|rcsb pdb:4OO6|rcsb pdb:5J3V|rcsb pdb:5TQC|rcsb pdb:5YVG|rcsb pdb:5YVH|rcsb pdb:5YVI|rcsb pdb:7CYL|reactome:R-HSA-450513|reactome:R-HSA-5620924|reactome:R-HSA-9615933 - - - figure legend:Supp Table S4 and Supp Fig. S3|comment:"Coimmunoprecipitation with 34ED229 (T2) anti-TEX101 antibody"|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-testis)|taxid:9606(Homo sapiens) - 2020/03/24 2020/06/18 rogid:ZE4tXTFi7lUCcIbCL4KHzY3a6xM9606 rogid:n8Q3n1rmTiJAp6f8DBcBV6j6lac9606 rigid:2wTqH12DHkSLcixvnxiJPZhqAc0 false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9BY14 uniprotkb:O00232 intact:EBI-12549378|ensembl:ENSP00000472769|uniprotkb:Q7L5R2|uniprotkb:Q9BPY7 intact:EBI-359733|uniprotkb:Q53HA2|uniprotkb:Q6P053|ensembl:ENSP00000348442|uniprotkb:A6NP15 psi-mi:tx101_human(display_long)|uniprotkb:TEX101(gene name)|psi-mi:TEX101(display_short)|uniprotkb:Cell surface receptor NYD-SP8(gene name synonym)|uniprotkb:SGRG(gene name synonym)|uniprotkb:Scleroderma-associated autoantigen(gene name synonym)|uniprotkb:Spermatogenesis-related gene protein(gene name synonym)|uniprotkb:UNQ867/PRO1884(orf name) psi-mi:psd12_human(display_long)|uniprotkb:PSMD12(gene name)|psi-mi:PSMD12(display_short)|uniprotkb:26S proteasome regulatory subunit p55(gene name synonym)|uniprotkb:26S proteasome regulatory subunit RPN5(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Schiza et al. (2018) imex:IM-28077|pubmed:30097533 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-25504841|imex:IM-28077-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000131126(gene)|ensembl:ENST00000598265(transcript)|go:"GO:0001669"(acrosomal vesicle)|go:"GO:0002080"(acrosomal membrane)|go:"GO:0005576"(extracellular region)|go:"GO:0005886"(plasma membrane)|go:"GO:0007339"(binding of sperm to zona pellucida)|go:"GO:0009566"(fertilization)|go:"GO:0030317"(flagellated sperm motility)|go:"GO:0044853"(plasma membrane raft)|go:"GO:0046658"(anchored component of plasma membrane)|go:"GO:1901317"(regulation of flagellated sperm motility)|interpro:IPR016054(Ly-6 antigen / uPA receptor -like)|rcsb pdb:7BPR|reactome:R-HSA-163125|refseq:NP_001123483.1|refseq:NP_113639.4 refseq:NP_002807.1|refseq:NP_001303270.1|ensembl:ENSG00000197170(gene)|ensembl:ENST00000356126(transcript)|go:"GO:0000502"(proteasome complex)|go:"GO:0005576"(extracellular region)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005838"(proteasome regulatory particle)|go:"GO:0008541"(proteasome regulatory particle, lid subcomplex)|go:"GO:0016020"(membrane)|go:"GO:0022624"(proteasome accessory complex)|go:"GO:0031595"(nuclear proteasome complex)|go:"GO:0034774"(secretory granule lumen)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0070062"(extracellular exosome)|go:"GO:1904813"(ficolin-1-rich granule lumen)|interpro:IPR000717(Proteasome component region PCI)|interpro:IPR035297|interpro:IPR036388|interpro:IPR036390|interpro:IPR040134|interpro:IPR040896|mint:O00232|rcsb pdb:5GJQ|rcsb pdb:5GJR|rcsb pdb:5L4K|rcsb pdb:5LN3|rcsb pdb:5M32|rcsb pdb:5T0C|rcsb pdb:5T0G|rcsb pdb:5T0H|rcsb pdb:5T0I|rcsb pdb:5T0J|rcsb pdb:5VFP|rcsb pdb:5VFQ|rcsb pdb:5VFR|rcsb pdb:5VFT|rcsb pdb:5VFU|rcsb pdb:5VGZ|rcsb pdb:5VHF|rcsb pdb:5VHH|rcsb pdb:5VHI|rcsb pdb:5VHS|rcsb pdb:6MSB|rcsb pdb:6MSD|rcsb pdb:6MSE|rcsb pdb:6MSG|rcsb pdb:6MSH|rcsb pdb:6MSJ|rcsb pdb:6MSK|rcsb pdb:6WJD|rcsb pdb:6WJN|reactome:R-HSA-1169091|reactome:R-HSA-1234176|reactome:R-HSA-1236974|rcsb pdb:5VFS|reactome:R-HSA-1236978|reactome:R-HSA-174084|reactome:R-HSA-174113|reactome:R-HSA-174154|reactome:R-HSA-174178|reactome:R-HSA-174184|reactome:R-HSA-180534|reactome:R-HSA-180585|reactome:R-HSA-187577|reactome:R-HSA-195253|reactome:R-HSA-202424|reactome:R-HSA-211733|reactome:R-HSA-2467813|reactome:R-HSA-2871837|reactome:R-HSA-349425|reactome:R-HSA-350562|reactome:R-HSA-382556|reactome:R-HSA-450408|reactome:R-HSA-4608870|reactome:R-HSA-4641257|reactome:R-HSA-4641258|reactome:R-HSA-5358346|reactome:R-HSA-5362768|reactome:R-HSA-5607761|reactome:R-HSA-5607764|reactome:R-HSA-5610780|reactome:R-HSA-5610783|reactome:R-HSA-5610785|reactome:R-HSA-5632684|reactome:R-HSA-5658442|reactome:R-HSA-5668541|reactome:R-HSA-5676590|reactome:R-HSA-5678895|reactome:R-HSA-5689603|reactome:R-HSA-5689880|reactome:R-HSA-6798695|reactome:R-HSA-68827|reactome:R-HSA-5687128|reactome:R-HSA-68949|reactome:R-HSA-69017|reactome:R-HSA-69481|reactome:R-HSA-69601|reactome:R-HSA-75815|reactome:R-HSA-8852276|reactome:R-HSA-8854050|reactome:R-HSA-8932339|reactome:R-HSA-8939236|reactome:R-HSA-8939902|reactome:R-HSA-8941858|reactome:R-HSA-8948751|reactome:R-HSA-8951664|reactome:R-HSA-9010553|reactome:R-HSA-9020702|reactome:R-HSA-9604323|reactome:R-HSA-983168|refseq:NP_777360.1|dip:DIP-27549N - - - figure legend:Supp Table S4 and Supp Fig. S3|comment:"Coimmunoprecipitation with 34ED229 (T2) anti-TEX101 antibody"|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-testis)|taxid:9606(Homo sapiens) - 2020/03/24 2020/06/18 rogid:ZE4tXTFi7lUCcIbCL4KHzY3a6xM9606 rogid:4tzcvfL/EqQRcUpoMtxVU0WC+TU9606 rigid:2wTqH12DHkSLcixvnxiJPZhqAc0 false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9BY14 uniprotkb:P04843 intact:EBI-12549378|ensembl:ENSP00000472769|uniprotkb:Q7L5R2|uniprotkb:Q9BPY7 intact:EBI-355963|ensembl:ENSP00000296255|uniprotkb:D3DNB6|uniprotkb:Q68DT1|uniprotkb:B2R5Z0 psi-mi:tx101_human(display_long)|uniprotkb:TEX101(gene name)|psi-mi:TEX101(display_short)|uniprotkb:Cell surface receptor NYD-SP8(gene name synonym)|uniprotkb:SGRG(gene name synonym)|uniprotkb:Scleroderma-associated autoantigen(gene name synonym)|uniprotkb:Spermatogenesis-related gene protein(gene name synonym)|uniprotkb:UNQ867/PRO1884(orf name) psi-mi:rpn1_human(display_long)|uniprotkb:RPN1(gene name)|psi-mi:RPN1(display_short)|uniprotkb:Dolichyl-diphosphooligosaccharide--protein glycosyltransferase 67 kDa subunit(gene name synonym)|uniprotkb:Ribophorin-1(gene name synonym)|uniprotkb:Ribophorin I(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Schiza et al. (2018) imex:IM-28077|pubmed:30097533 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-25504841|imex:IM-28077-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000131126(gene)|ensembl:ENST00000598265(transcript)|go:"GO:0001669"(acrosomal vesicle)|go:"GO:0002080"(acrosomal membrane)|go:"GO:0005576"(extracellular region)|go:"GO:0005886"(plasma membrane)|go:"GO:0007339"(binding of sperm to zona pellucida)|go:"GO:0009566"(fertilization)|go:"GO:0030317"(flagellated sperm motility)|go:"GO:0044853"(plasma membrane raft)|go:"GO:0046658"(anchored component of plasma membrane)|go:"GO:1901317"(regulation of flagellated sperm motility)|interpro:IPR016054(Ly-6 antigen / uPA receptor -like)|rcsb pdb:7BPR|reactome:R-HSA-163125|refseq:NP_001123483.1|refseq:NP_113639.4 ensembl:ENSG00000163902(gene)|ensembl:ENST00000296255(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005791"(rough endoplasmic reticulum)|go:"GO:0005829"(cytosol)|go:"GO:0006487"(protein N-linked glycosylation)|go:"GO:0008250"(oligosaccharyltransferase complex)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0018279"(protein N-linked glycosylation via asparagine)|go:"GO:0042470"(melanosome)|interpro:IPR007676(Ribophorin I)|mint:P04843|rcsb pdb:6S7O|rcsb pdb:6S7T|reactome:R-HSA-1799339|reactome:R-HSA-446203|reactome:R-HSA-9694548|go:"GO:0006464"(cellular protein modification process)|refseq:NP_002941.1|dip:DIP-38152N - - - figure legend:Supp Table S4 and Supp Fig. S3|comment:"Coimmunoprecipitation with 34ED229 (T2) anti-TEX101 antibody"|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-testis)|taxid:9606(Homo sapiens) - 2020/03/24 2020/06/18 rogid:ZE4tXTFi7lUCcIbCL4KHzY3a6xM9606 rogid:rvQThNB/dCCNR9+IDssZo1qgZUE9606 rigid:2wTqH12DHkSLcixvnxiJPZhqAc0 false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9BY14 uniprotkb:P31939 intact:EBI-12549378|ensembl:ENSP00000472769|uniprotkb:Q7L5R2|uniprotkb:Q9BPY7 intact:EBI-1048599|uniprotkb:Q13856|uniprotkb:Q53S28|uniprotkb:A8K202|uniprotkb:E9PBU3|ensembl:ENSP00000236959 psi-mi:tx101_human(display_long)|uniprotkb:TEX101(gene name)|psi-mi:TEX101(display_short)|uniprotkb:Cell surface receptor NYD-SP8(gene name synonym)|uniprotkb:SGRG(gene name synonym)|uniprotkb:Scleroderma-associated autoantigen(gene name synonym)|uniprotkb:Spermatogenesis-related gene protein(gene name synonym)|uniprotkb:UNQ867/PRO1884(orf name) psi-mi:pur9_human(display_long)|uniprotkb:ATIC(gene name)|psi-mi:ATIC(display_short)|uniprotkb:PURH(gene name synonym)|uniprotkb:OK/SW-cl.86(orf name)|uniprotkb:AICAR transformylase/inosine monophosphate cyclohydrolase(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Schiza et al. (2018) imex:IM-28077|pubmed:30097533 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-25504841|imex:IM-28077-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000131126(gene)|ensembl:ENST00000598265(transcript)|go:"GO:0001669"(acrosomal vesicle)|go:"GO:0002080"(acrosomal membrane)|go:"GO:0005576"(extracellular region)|go:"GO:0005886"(plasma membrane)|go:"GO:0007339"(binding of sperm to zona pellucida)|go:"GO:0009566"(fertilization)|go:"GO:0030317"(flagellated sperm motility)|go:"GO:0044853"(plasma membrane raft)|go:"GO:0046658"(anchored component of plasma membrane)|go:"GO:1901317"(regulation of flagellated sperm motility)|interpro:IPR016054(Ly-6 antigen / uPA receptor -like)|rcsb pdb:7BPR|reactome:R-HSA-163125|refseq:NP_001123483.1|refseq:NP_113639.4 refseq:NP_004035.2|ensembl:ENSG00000138363(gene)|ensembl:ENST00000236959(transcript)|go:"GO:0003360"(brainstem development)|go:"GO:0003937"(IMP cyclohydrolase activity)|go:"GO:0004643"(phosphoribosylaminoimidazolecarboxamide formyltransferase activity)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006139"(nucleobase-containing compound metabolic process)|go:"GO:0006189"('de novo' IMP biosynthetic process)|go:"GO:0009116"(nucleoside metabolic process)|go:"GO:0010035"(response to inorganic substance)|go:"GO:0016020"(membrane)|go:"GO:0021549"(cerebellum development)|go:"GO:0021987"(cerebral cortex development)|go:"GO:0031100"(animal organ regeneration)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0045296"(cadherin binding)|go:"GO:0046452"(dihydrofolate metabolic process)|go:"GO:0046654"(tetrahydrofolate biosynthetic process)|go:"GO:0070062"(extracellular exosome)|go:"GO:0098761"(cellular response to interleukin-7)|interpro:IPR002695(AICARFT/IMPCHase bienzyme)|interpro:IPR011607(MGS-like)|interpro:IPR016193(Cytidine deaminase-like)|interpro:IPR024050|interpro:IPR024051|interpro:IPR036914|rcsb pdb:1P4R|rcsb pdb:1PKX|rcsb pdb:1PL0|rcsb pdb:5UY8|rcsb pdb:5UZ0|reactome:R-HSA-73817 - - - figure legend:Supp Table S4 and Supp Fig. S3|comment:"Coimmunoprecipitation with 34ED229 (T2) anti-TEX101 antibody"|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-testis)|taxid:9606(Homo sapiens) - 2020/03/24 2020/06/18 rogid:ZE4tXTFi7lUCcIbCL4KHzY3a6xM9606 rogid:Xe3388w/LOBYgag9P8Gp3IGo9wU9606 rigid:2wTqH12DHkSLcixvnxiJPZhqAc0 false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9BY14 uniprotkb:P22102 intact:EBI-12549378|ensembl:ENSP00000472769|uniprotkb:Q7L5R2|uniprotkb:Q9BPY7 intact:EBI-356297|ensembl:ENSP00000371236|ensembl:ENSP00000371253|ensembl:ENSP00000371261|ensembl:ENSP00000459391|ensembl:ENSP00000459532|ensembl:ENSP00000461700|uniprotkb:D3DSF3|uniprotkb:D3DSF4|uniprotkb:O14659|uniprotkb:A8KA32|uniprotkb:A8K945|uniprotkb:Q52M77 psi-mi:tx101_human(display_long)|uniprotkb:TEX101(gene name)|psi-mi:TEX101(display_short)|uniprotkb:Cell surface receptor NYD-SP8(gene name synonym)|uniprotkb:SGRG(gene name synonym)|uniprotkb:Scleroderma-associated autoantigen(gene name synonym)|uniprotkb:Spermatogenesis-related gene protein(gene name synonym)|uniprotkb:UNQ867/PRO1884(orf name) psi-mi:pur2_human(display_long)|uniprotkb:GART(gene name)|psi-mi:GART(display_short)|uniprotkb:PRGS(gene name synonym)|uniprotkb:PGFT(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Schiza et al. (2018) imex:IM-28077|pubmed:30097533 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-25504841|imex:IM-28077-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000131126(gene)|ensembl:ENST00000598265(transcript)|go:"GO:0001669"(acrosomal vesicle)|go:"GO:0002080"(acrosomal membrane)|go:"GO:0005576"(extracellular region)|go:"GO:0005886"(plasma membrane)|go:"GO:0007339"(binding of sperm to zona pellucida)|go:"GO:0009566"(fertilization)|go:"GO:0030317"(flagellated sperm motility)|go:"GO:0044853"(plasma membrane raft)|go:"GO:0046658"(anchored component of plasma membrane)|go:"GO:1901317"(regulation of flagellated sperm motility)|interpro:IPR016054(Ly-6 antigen / uPA receptor -like)|rcsb pdb:7BPR|reactome:R-HSA-163125|refseq:NP_001123483.1|refseq:NP_113639.4 go:"GO:0006164"(purine nucleotide biosynthetic process)|go:"GO:0006189"('de novo' IMP biosynthetic process)|go:"GO:0006544"(glycine metabolic process)|go:"GO:0009168"(purine ribonucleoside monophosphate biosynthetic process)|go:"GO:0010033"(response to organic substance)|go:"GO:0010035"(response to inorganic substance)|go:"GO:0021549"(cerebellum development)|go:"GO:0021987"(cerebral cortex development)|go:"GO:0046084"(adenine biosynthetic process)|go:"GO:0046654"(tetrahydrofolate biosynthetic process)|go:"GO:0046872"(metal ion binding)|go:"GO:0070062"(extracellular exosome)|interpro:IPR000115(Phosphoribosylglycinamide synthetase)|interpro:IPR001555(Phosphoribosylglycinamide formyltransferase, active site)|interpro:IPR002376(Formyl transferase, N-terminal)|interpro:IPR004607(Phosphoribosylglycinamide formyltransferase)|interpro:IPR004733(Phosphoribosylformylglycinamidine cyclo-ligase)|interpro:IPR010918(AIR synthase related protein, C-terminal)|ensembl:ENST00000571089(transcript)|interpro:IPR011054(Rudiment single hybrid motif)|interpro:IPR011761(ATP-grasp fold)|ensembl:ENST00000573055(transcript)|ensembl:ENST00000575273(transcript)|go:"GO:0003360"(brainstem development)|go:"GO:0004637"(phosphoribosylamine-glycine ligase activity)|go:"GO:0004641"(phosphoribosylformylglycinamidine cyclo-ligase activity)|interpro:IPR013815(ATP-grasp fold, subdomain 1)|go:"GO:0004644"(phosphoribosylglycinamide formyltransferase activity)|interpro:IPR016185(PreATP-grasp-like fold)|go:"GO:0005524"(ATP binding)|go:"GO:0005829"(cytosol)|interpro:IPR016188(PurM, N-terminal-like)|ensembl:ENSG00000159131(gene)|ensembl:ENSG00000262473(gene)|ensembl:ENST00000381815(transcript)|ensembl:ENST00000381831(transcript)|ensembl:ENST00000381839(transcript)|interpro:IPR020560|interpro:IPR020561|interpro:IPR020562|interpro:IPR036477|interpro:IPR036676|interpro:IPR036921|interpro:IPR037123|mint:P22102|rcsb pdb:1MEJ|rcsb pdb:1MEN|rcsb pdb:1MEO|rcsb pdb:1NJS|rcsb pdb:1RBM|rcsb pdb:1RBQ|rcsb pdb:1RBY|rcsb pdb:1RBZ|rcsb pdb:1RC0|rcsb pdb:1RC1|rcsb pdb:1ZLX|rcsb pdb:1ZLY|rcsb pdb:2QK4|rcsb pdb:2V9Y|rcsb pdb:4EW1|rcsb pdb:4EW2|rcsb pdb:4EW3|rcsb pdb:4ZYT|interpro:IPR020559|rcsb pdb:4ZYU|rcsb pdb:4ZYV|rcsb pdb:4ZYW|rcsb pdb:4ZYX|rcsb pdb:4ZYY|rcsb pdb:4ZYZ|rcsb pdb:4ZZ0|rcsb pdb:4ZZ1|rcsb pdb:4ZZ2|rcsb pdb:5J9F|rcsb pdb:7JG0|rcsb pdb:4ZZ3|refseq:NP_000810.1|refseq:NP_001129477.1|refseq:NP_001129478.1|refseq:NP_780294.1|rcsb pdb:7JG4|reactome:R-HSA-73817|rcsb pdb:7JG3|refseq:XP_011527828.1|refseq:XP_006724052.1|refseq:XP_006724053.1|refseq:XP_005260998.1 - - - figure legend:Supp Table S4 and Supp Fig. S3|comment:"Coimmunoprecipitation with 34ED229 (T2) anti-TEX101 antibody"|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-testis)|taxid:9606(Homo sapiens) - 2020/03/24 2020/06/18 rogid:ZE4tXTFi7lUCcIbCL4KHzY3a6xM9606 rogid:7Iy33CtBsB8LHZFDP5mZ3eRX8pU9606 rigid:2wTqH12DHkSLcixvnxiJPZhqAc0 false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9BY14 uniprotkb:P10696 intact:EBI-12549378|ensembl:ENSP00000472769|uniprotkb:Q7L5R2|uniprotkb:Q9BPY7 intact:EBI-2557899|uniprotkb:Q96CM1|uniprotkb:A8KAF2|uniprotkb:Q16727|uniprotkb:Q53S81|ensembl:ENSP00000295453 psi-mi:tx101_human(display_long)|uniprotkb:TEX101(gene name)|psi-mi:TEX101(display_short)|uniprotkb:Cell surface receptor NYD-SP8(gene name synonym)|uniprotkb:SGRG(gene name synonym)|uniprotkb:Scleroderma-associated autoantigen(gene name synonym)|uniprotkb:Spermatogenesis-related gene protein(gene name synonym)|uniprotkb:UNQ867/PRO1884(orf name) psi-mi:ppbn_human(display_long)|uniprotkb:ALPG(gene name)|psi-mi:ALPG(display_short)|uniprotkb:ALP-1(gene name synonym)|uniprotkb:ALPPL(gene name synonym)|uniprotkb:ALPPL2(gene name synonym)|uniprotkb:Alkaline phosphatase Nagao isozyme(gene name synonym)|uniprotkb:Alkaline phosphatase, placental-like(gene name synonym)|uniprotkb:Germ cell alkaline phosphatase(gene name synonym)|uniprotkb:Placental alkaline phosphatase-like(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Schiza et al. (2018) imex:IM-28077|pubmed:30097533 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-25504841|imex:IM-28077-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000131126(gene)|ensembl:ENST00000598265(transcript)|go:"GO:0001669"(acrosomal vesicle)|go:"GO:0002080"(acrosomal membrane)|go:"GO:0005576"(extracellular region)|go:"GO:0005886"(plasma membrane)|go:"GO:0007339"(binding of sperm to zona pellucida)|go:"GO:0009566"(fertilization)|go:"GO:0030317"(flagellated sperm motility)|go:"GO:0044853"(plasma membrane raft)|go:"GO:0046658"(anchored component of plasma membrane)|go:"GO:1901317"(regulation of flagellated sperm motility)|interpro:IPR016054(Ly-6 antigen / uPA receptor -like)|rcsb pdb:7BPR|reactome:R-HSA-163125|refseq:NP_001123483.1|refseq:NP_113639.4 refseq:NP_112603.2|ensembl:ENSG00000163286(gene)|ensembl:ENST00000295453(transcript)|go:"GO:0004035"(alkaline phosphatase activity)|go:"GO:0005576"(extracellular region)|go:"GO:0005886"(plasma membrane)|go:"GO:0016311"(dephosphorylation)|go:"GO:0031225"(anchored component of membrane)|go:"GO:0046872"(metal ion binding)|interpro:IPR001952(Alkaline phosphatase)|interpro:IPR017850(Alkaline-phosphatase-like, core domain)|interpro:IPR018299|reactome:R-HSA-163125 - - - figure legend:Supp Table S4 and Supp Fig. S3|comment:"Coimmunoprecipitation with 34ED229 (T2) anti-TEX101 antibody"|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-testis)|taxid:9606(Homo sapiens) - 2020/03/24 2020/06/18 rogid:ZE4tXTFi7lUCcIbCL4KHzY3a6xM9606 rogid:7+Mu+FXW0V3WQbaWO0u083e6Jc09606 rigid:2wTqH12DHkSLcixvnxiJPZhqAc0 false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9BY14 uniprotkb:P63151 intact:EBI-12549378|ensembl:ENSP00000472769|uniprotkb:Q7L5R2|uniprotkb:Q9BPY7 intact:EBI-1048931|uniprotkb:P50409|uniprotkb:Q00007|uniprotkb:B2RBU8|intact:EBI-2556013|uniprotkb:B4E1T7|ensembl:ENSP00000370113 psi-mi:tx101_human(display_long)|uniprotkb:TEX101(gene name)|psi-mi:TEX101(display_short)|uniprotkb:Cell surface receptor NYD-SP8(gene name synonym)|uniprotkb:SGRG(gene name synonym)|uniprotkb:Scleroderma-associated autoantigen(gene name synonym)|uniprotkb:Spermatogenesis-related gene protein(gene name synonym)|uniprotkb:UNQ867/PRO1884(orf name) psi-mi:2aba_human(display_long)|uniprotkb:PPP2R2A(gene name)|psi-mi:PPP2R2A(display_short)|uniprotkb:PP2A subunit B isoform alpha(gene name synonym)|uniprotkb:PP2A subunit B isoform B55-alpha(gene name synonym)|uniprotkb:PP2A subunit B isoform PR55-alpha(gene name synonym)|uniprotkb:PP2A subunit B isoform R2-alpha(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Schiza et al. (2018) imex:IM-28077|pubmed:30097533 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-25504841|imex:IM-28077-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000131126(gene)|ensembl:ENST00000598265(transcript)|go:"GO:0001669"(acrosomal vesicle)|go:"GO:0002080"(acrosomal membrane)|go:"GO:0005576"(extracellular region)|go:"GO:0005886"(plasma membrane)|go:"GO:0007339"(binding of sperm to zona pellucida)|go:"GO:0009566"(fertilization)|go:"GO:0030317"(flagellated sperm motility)|go:"GO:0044853"(plasma membrane raft)|go:"GO:0046658"(anchored component of plasma membrane)|go:"GO:1901317"(regulation of flagellated sperm motility)|interpro:IPR016054(Ly-6 antigen / uPA receptor -like)|rcsb pdb:7BPR|reactome:R-HSA-163125|refseq:NP_001123483.1|refseq:NP_113639.4 refseq:NP_001171062.1|refseq:NP_002708.1|ensembl:ENSG00000221914(gene)|ensembl:ENST00000380737(transcript)|go:"GO:0000159"(protein phosphatase type 2A complex)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006470"(protein dephosphorylation)|go:"GO:0019888"(protein phosphatase regulator activity)|go:"GO:0043278"(response to morphine)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0048156"(tau protein binding)|go:"GO:0051721"(protein phosphatase 2A binding)|go:"GO:0070262"(peptidyl-serine dephosphorylation)|go:"GO:0098978"(glutamatergic synapse)|interpro:IPR000009(Protein phosphatase 2A, regulatory subunit PR55)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR018067|interpro:IPR036322|mint:P63151|rcsb pdb:3DW8|reactome:R-HSA-2995383|reactome:R-HSA-69231|reactome:R-HSA-69273|reactome:R-HSA-975957|dip:DIP-29398N - - - figure legend:Supp Table S4 and Supp Fig. S3|comment:"Coimmunoprecipitation with 34ED229 (T2) anti-TEX101 antibody"|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-testis)|taxid:9606(Homo sapiens) - 2020/03/24 2020/06/18 rogid:ZE4tXTFi7lUCcIbCL4KHzY3a6xM9606 rogid:evS6klM2alZXtMthVsshKkrNgiA9606 rigid:2wTqH12DHkSLcixvnxiJPZhqAc0 false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9BY14 uniprotkb:O76003 intact:EBI-12549378|ensembl:ENSP00000472769|uniprotkb:Q7L5R2|uniprotkb:Q9BPY7 intact:EBI-374781|uniprotkb:Q96CE0|uniprotkb:Q9P1B0|uniprotkb:Q9P1B1|uniprotkb:B3KMP7|uniprotkb:B3KMQ5|uniprotkb:Q5JV01|ensembl:ENSP00000330836|ensembl:ENSP00000357633|ensembl:ENSP00000435445|uniprotkb:D3DRG2 psi-mi:tx101_human(display_long)|uniprotkb:TEX101(gene name)|psi-mi:TEX101(display_short)|uniprotkb:Cell surface receptor NYD-SP8(gene name synonym)|uniprotkb:SGRG(gene name synonym)|uniprotkb:Scleroderma-associated autoantigen(gene name synonym)|uniprotkb:Spermatogenesis-related gene protein(gene name synonym)|uniprotkb:UNQ867/PRO1884(orf name) psi-mi:glrx3_human(display_long)|uniprotkb:GLRX3(gene name)|psi-mi:GLRX3(display_short)|uniprotkb:Thioredoxin-like protein 2(gene name synonym)|uniprotkb:PKC-interacting cousin of thioredoxin(gene name synonym)|uniprotkb:PKC-theta-interacting protein(gene name synonym)|uniprotkb:PICOT(gene name synonym)|uniprotkb:HUSSY-22(orf name)|uniprotkb:TXNL2(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Schiza et al. (2018) imex:IM-28077|pubmed:30097533 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-25504841|imex:IM-28077-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000131126(gene)|ensembl:ENST00000598265(transcript)|go:"GO:0001669"(acrosomal vesicle)|go:"GO:0002080"(acrosomal membrane)|go:"GO:0005576"(extracellular region)|go:"GO:0005886"(plasma membrane)|go:"GO:0007339"(binding of sperm to zona pellucida)|go:"GO:0009566"(fertilization)|go:"GO:0030317"(flagellated sperm motility)|go:"GO:0044853"(plasma membrane raft)|go:"GO:0046658"(anchored component of plasma membrane)|go:"GO:1901317"(regulation of flagellated sperm motility)|interpro:IPR016054(Ly-6 antigen / uPA receptor -like)|rcsb pdb:7BPR|reactome:R-HSA-163125|refseq:NP_001123483.1|refseq:NP_113639.4 ensembl:ENSG00000108010(gene)|ensembl:ENST00000331244(transcript)|ensembl:ENST00000368644(transcript)|ensembl:ENST00000481034(transcript)|go:"GO:0002026"(regulation of the force of heart contraction)|go:"GO:0003723"(RNA binding)|go:"GO:0005080"(protein kinase C binding)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0005938"(cell cortex)|go:"GO:0006879"(cellular iron ion homeostasis)|go:"GO:0010614"(negative regulation of cardiac muscle hypertrophy)|go:"GO:0030018"(Z disc)|go:"GO:0030425"(dendrite)|go:"GO:0042802"(identical protein binding)|go:"GO:0044571"([2Fe-2S] cluster assembly)|go:"GO:0046872"(metal ion binding)|go:"GO:0051536"(iron-sulfur cluster binding)|go:"GO:0097428"(protein maturation by iron-sulfur cluster transfer)|go:"GO:0097573"(glutathione oxidoreductase activity)|interpro:IPR002109(Glutaredoxin)|interpro:IPR004480(Glutaredoxin-related protein)|interpro:IPR013766(Thioredoxin domain)|interpro:IPR033658|interpro:IPR036249|mint:O76003|rcsb pdb:2DIY|rcsb pdb:2WZ9|rcsb pdb:2YAN|rcsb pdb:3ZYW|reactome:R-HSA-917937|refseq:NP_001186797.1|refseq:NP_006532.2|dip:DIP-31306N - - - figure legend:Supp Table S4 and Supp Fig. S3|comment:"Coimmunoprecipitation with 34ED229 (T2) anti-TEX101 antibody"|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-testis)|taxid:9606(Homo sapiens) - 2020/03/24 2020/06/18 rogid:ZE4tXTFi7lUCcIbCL4KHzY3a6xM9606 rogid:iKUSt6zbNzzXSKvW+vXMq3hKsEM9606 rigid:2wTqH12DHkSLcixvnxiJPZhqAc0 false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9BY14 uniprotkb:P50453 intact:EBI-12549378|ensembl:ENSP00000472769|uniprotkb:Q7L5R2|uniprotkb:Q9BPY7 intact:EBI-711626|uniprotkb:Q5TD03|uniprotkb:B2RBW3|ensembl:ENSP00000370074 psi-mi:tx101_human(display_long)|uniprotkb:TEX101(gene name)|psi-mi:TEX101(display_short)|uniprotkb:Cell surface receptor NYD-SP8(gene name synonym)|uniprotkb:SGRG(gene name synonym)|uniprotkb:Scleroderma-associated autoantigen(gene name synonym)|uniprotkb:Spermatogenesis-related gene protein(gene name synonym)|uniprotkb:UNQ867/PRO1884(orf name) psi-mi:spb9_human(display_long)|uniprotkb:SERPINB9(gene name)|psi-mi:SERPINB9(display_short)|uniprotkb:PI9(gene name synonym)|uniprotkb:Cytoplasmic antiproteinase 3(gene name synonym)|uniprotkb:Peptidase inhibitor 9(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Schiza et al. (2018) imex:IM-28077|pubmed:30097533 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-25504841|imex:IM-28077-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000131126(gene)|ensembl:ENST00000598265(transcript)|go:"GO:0001669"(acrosomal vesicle)|go:"GO:0002080"(acrosomal membrane)|go:"GO:0005576"(extracellular region)|go:"GO:0005886"(plasma membrane)|go:"GO:0007339"(binding of sperm to zona pellucida)|go:"GO:0009566"(fertilization)|go:"GO:0030317"(flagellated sperm motility)|go:"GO:0044853"(plasma membrane raft)|go:"GO:0046658"(anchored component of plasma membrane)|go:"GO:1901317"(regulation of flagellated sperm motility)|interpro:IPR016054(Ly-6 antigen / uPA receptor -like)|rcsb pdb:7BPR|reactome:R-HSA-163125|refseq:NP_001123483.1|refseq:NP_113639.4 ensembl:ENSG00000170542(gene)|ensembl:ENST00000380698(transcript)|go:"GO:0002020"(protease binding)|refseq:NP_004146.1|refseq:XP_005249241.1|go:"GO:0043027"(cysteine-type endopeptidase inhibitor activity involved in apoptotic process)|go:"GO:0004867"(serine-type endopeptidase inhibitor activity)|go:"GO:0005615"(extracellular space)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0006955"(immune response)|go:"GO:0009617"(response to bacterium)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010951"(negative regulation of endopeptidase activity)|go:"GO:0016020"(membrane)|go:"GO:0033668"(negative regulation by symbiont of host apoptotic process)|go:"GO:0042270"(protection from natural killer cell mediated cytotoxicity)|go:"GO:0002448"(mast cell mediated immunity)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0062023"(collagen-containing extracellular matrix)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071391"(cellular response to estrogen stimulus)|interpro:IPR000215(Protease inhibitor I4, serpin)|interpro:IPR000240(Serpin B9 and maspin)|interpro:IPR023795|interpro:IPR023796|interpro:IPR036186|interpro:IPR042178|interpro:IPR042185 - - - figure legend:Supp Table S4 and Supp Fig. S3|comment:"Coimmunoprecipitation with 34ED229 (T2) anti-TEX101 antibody"|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-testis)|taxid:9606(Homo sapiens) - 2020/03/24 2020/06/18 rogid:ZE4tXTFi7lUCcIbCL4KHzY3a6xM9606 rogid:BFT8YUM1DhX4hjTmzVI4pZbOqxk9606 rigid:2wTqH12DHkSLcixvnxiJPZhqAc0 false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9BY14 uniprotkb:Q9ULL0 intact:EBI-12549378|ensembl:ENSP00000472769|uniprotkb:Q7L5R2|uniprotkb:Q9BPY7 intact:EBI-25504943|ensembl:ENSP00000384670|uniprotkb:B7ZCI8|uniprotkb:Q5JPN4 psi-mi:tx101_human(display_long)|uniprotkb:TEX101(gene name)|psi-mi:TEX101(display_short)|uniprotkb:Cell surface receptor NYD-SP8(gene name synonym)|uniprotkb:SGRG(gene name synonym)|uniprotkb:Scleroderma-associated autoantigen(gene name synonym)|uniprotkb:Spermatogenesis-related gene protein(gene name synonym)|uniprotkb:UNQ867/PRO1884(orf name) psi-mi:k1210_human(display_long)|uniprotkb:KIAA1210(gene name)|psi-mi:KIAA1210(display_short) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Schiza et al. (2018) imex:IM-28077|pubmed:30097533 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-25504841|imex:IM-28077-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000131126(gene)|ensembl:ENST00000598265(transcript)|go:"GO:0001669"(acrosomal vesicle)|go:"GO:0002080"(acrosomal membrane)|go:"GO:0005576"(extracellular region)|go:"GO:0005886"(plasma membrane)|go:"GO:0007339"(binding of sperm to zona pellucida)|go:"GO:0009566"(fertilization)|go:"GO:0030317"(flagellated sperm motility)|go:"GO:0044853"(plasma membrane raft)|go:"GO:0046658"(anchored component of plasma membrane)|go:"GO:1901317"(regulation of flagellated sperm motility)|interpro:IPR016054(Ly-6 antigen / uPA receptor -like)|rcsb pdb:7BPR|reactome:R-HSA-163125|refseq:NP_001123483.1|refseq:NP_113639.4 ensembl:ENSP00000384670|ensembl:ENSG00000250423(gene)|ensembl:ENST00000402510(transcript)|go:"GO:0001669"(acrosomal vesicle)|interpro:IPR026713|interpro:IPR028030|refseq:NP_065772.1 - - - figure legend:Supp Table S4 and Supp Fig. S3|comment:"Coimmunoprecipitation with 34ED229 (T2) anti-TEX101 antibody"|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-testis)|taxid:9606(Homo sapiens) - 2020/03/24 2020/06/18 rogid:ZE4tXTFi7lUCcIbCL4KHzY3a6xM9606 rogid:F8Wj2c1kwepOD2MEt/aXQq19e1s9606 rigid:2wTqH12DHkSLcixvnxiJPZhqAc0 false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9BY14 uniprotkb:P07099 intact:EBI-12549378|ensembl:ENSP00000472769|uniprotkb:Q7L5R2|uniprotkb:Q9BPY7 intact:EBI-6138796|uniprotkb:B2R8N0|uniprotkb:Q5VTJ6|uniprotkb:Q9NP75|uniprotkb:Q9NPE7|uniprotkb:Q9NQU6|uniprotkb:Q9NQU7|uniprotkb:Q9NQU8|uniprotkb:Q9NQU9|uniprotkb:Q9NQV0|uniprotkb:Q9NQV1|uniprotkb:Q9NQV2|ensembl:ENSP00000272167|ensembl:ENSP00000355802|ensembl:ENSP00000480004 psi-mi:tx101_human(display_long)|uniprotkb:TEX101(gene name)|psi-mi:TEX101(display_short)|uniprotkb:Cell surface receptor NYD-SP8(gene name synonym)|uniprotkb:SGRG(gene name synonym)|uniprotkb:Scleroderma-associated autoantigen(gene name synonym)|uniprotkb:Spermatogenesis-related gene protein(gene name synonym)|uniprotkb:UNQ867/PRO1884(orf name) psi-mi:hyep_human(display_long)|uniprotkb:EPHX1(gene name)|psi-mi:EPHX1(display_short)|uniprotkb:EPHX(gene name synonym)|uniprotkb:EPOX(gene name synonym)|uniprotkb:Epoxide hydratase(gene name synonym)|uniprotkb:Microsomal epoxide hydrolase(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Schiza et al. (2018) imex:IM-28077|pubmed:30097533 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-25504841|imex:IM-28077-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000131126(gene)|ensembl:ENST00000598265(transcript)|go:"GO:0001669"(acrosomal vesicle)|go:"GO:0002080"(acrosomal membrane)|go:"GO:0005576"(extracellular region)|go:"GO:0005886"(plasma membrane)|go:"GO:0007339"(binding of sperm to zona pellucida)|go:"GO:0009566"(fertilization)|go:"GO:0030317"(flagellated sperm motility)|go:"GO:0044853"(plasma membrane raft)|go:"GO:0046658"(anchored component of plasma membrane)|go:"GO:1901317"(regulation of flagellated sperm motility)|interpro:IPR016054(Ly-6 antigen / uPA receptor -like)|rcsb pdb:7BPR|reactome:R-HSA-163125|refseq:NP_001123483.1|refseq:NP_113639.4 refseq:NP_001278092.1|refseq:NP_000111.1|refseq:NP_001129490.1|ensembl:ENSG00000143819(gene)|ensembl:ENST00000272167(transcript)|ensembl:ENST00000366837(transcript)|ensembl:ENST00000614058(transcript)|go:"GO:0004301"(epoxide hydrolase activity)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006805"(xenobiotic metabolic process)|go:"GO:0009636"(response to toxic substance)|go:"GO:0014070"(response to organic cyclic compound)|go:"GO:0016021"(integral component of membrane)|go:"GO:0019369"(arachidonic acid metabolic process)|go:"GO:0019439"(aromatic compound catabolic process)|go:"GO:0033961"(cis-stilbene-oxide hydrolase activity)|go:"GO:0097176"(epoxide metabolic process)|interpro:IPR000073(Alpha/beta hydrolase fold-1)|interpro:IPR000639(Epoxide hydrolase-like)|interpro:IPR016292(Epoxide hydrolase)|interpro:IPR029058|reactome:R-HSA-211945 - - - figure legend:Supp Table S4 and Supp Fig. S3|comment:"Coimmunoprecipitation with 34ED229 (T2) anti-TEX101 antibody"|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-testis)|taxid:9606(Homo sapiens) - 2020/03/24 2020/06/18 rogid:ZE4tXTFi7lUCcIbCL4KHzY3a6xM9606 rogid:VtIgDuQpQQbLSdFLOBBx9yHHiBE9606 rigid:2wTqH12DHkSLcixvnxiJPZhqAc0 false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9BY14 uniprotkb:P13861 intact:EBI-12549378|ensembl:ENSP00000472769|uniprotkb:Q7L5R2|uniprotkb:Q9BPY7 intact:EBI-2556122|intact:EBI-6116682|uniprotkb:Q9BUB1|uniprotkb:Q16823|ensembl:ENSP00000265563|ensembl:ENSP00000394041|intact:EBI-10961724 psi-mi:tx101_human(display_long)|uniprotkb:TEX101(gene name)|psi-mi:TEX101(display_short)|uniprotkb:Cell surface receptor NYD-SP8(gene name synonym)|uniprotkb:SGRG(gene name synonym)|uniprotkb:Scleroderma-associated autoantigen(gene name synonym)|uniprotkb:Spermatogenesis-related gene protein(gene name synonym)|uniprotkb:UNQ867/PRO1884(orf name) psi-mi:kap2_human(display_long)|uniprotkb:PKR2(gene name synonym)|uniprotkb:PRKAR2(gene name synonym)|uniprotkb:PRKAR2A(gene name)|psi-mi:PRKAR2A(display_short) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Schiza et al. (2018) imex:IM-28077|pubmed:30097533 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-25504841|imex:IM-28077-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000131126(gene)|ensembl:ENST00000598265(transcript)|go:"GO:0001669"(acrosomal vesicle)|go:"GO:0002080"(acrosomal membrane)|go:"GO:0005576"(extracellular region)|go:"GO:0005886"(plasma membrane)|go:"GO:0007339"(binding of sperm to zona pellucida)|go:"GO:0009566"(fertilization)|go:"GO:0030317"(flagellated sperm motility)|go:"GO:0044853"(plasma membrane raft)|go:"GO:0046658"(anchored component of plasma membrane)|go:"GO:1901317"(regulation of flagellated sperm motility)|interpro:IPR016054(Ly-6 antigen / uPA receptor -like)|rcsb pdb:7BPR|reactome:R-HSA-163125|refseq:NP_001123483.1|refseq:NP_113639.4 dip:DIP-552N|refseq:XP_011532244.1|interpro:IPR000595(Cyclic nucleotide-binding)|interpro:IPR003117(cAMP-dependent protein kinase, regulatory subunit, type I/II alpha/beta)|interpro:IPR012198(cAMP-dependent protein kinase regulatory subunit)|interpro:IPR014710(RmlC-like jelly roll fold)|interpro:IPR018488|interpro:IPR018490|mint:P13861|rcsb pdb:2IZX|rcsb pdb:2KYG|rcsb pdb:4ZP3|rcsb pdb:5H78|rcsb pdb:5XBY|reactome:R-HSA-163615|reactome:R-HSA-164378|reactome:R-HSA-180024|reactome:R-HSA-381676|reactome:R-HSA-432040|reactome:R-HSA-442720|reactome:R-HSA-5610787|reactome:R-HSA-9010642|reactome:R-HSA-9660821|reactome:R-HSA-9664323|reactome:R-HSA-983231|ensembl:ENSG00000114302(gene)|ensembl:ENST00000265563(transcript)|ensembl:ENST00000454963(transcript)|go:"GO:0004862"(cAMP-dependent protein kinase inhibitor activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005925"(focal adhesion)|go:"GO:0005952"(cAMP-dependent protein kinase complex)|go:"GO:0008603"(cAMP-dependent protein kinase regulator activity)|go:"GO:0010738"(regulation of protein kinase A signaling)|go:"GO:0016020"(membrane)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030552"(cAMP binding)|go:"GO:0031588"(nucleotide-activated protein kinase complex)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034236"(protein kinase A catalytic subunit binding)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0043949"(regulation of cAMP-mediated signaling)|go:"GO:0044853"(plasma membrane raft)|go:"GO:0070062"(extracellular exosome)|go:"GO:0097546"(ciliary base)|go:"GO:2000480"(negative regulation of cAMP-dependent protein kinase activity)|refseq:NP_001308911.1|refseq:NP_001308912.1|refseq:NP_004148.1|refseq:XP_016862304.1 - - - figure legend:Supp Table S4 and Supp Fig. S3|comment:"Coimmunoprecipitation with 34ED229 (T2) anti-TEX101 antibody"|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-testis)|taxid:9606(Homo sapiens) - 2020/03/24 2020/06/18 rogid:ZE4tXTFi7lUCcIbCL4KHzY3a6xM9606 rogid:9Jf7EDZ9CZjeRERWwLAR0NyqFGQ9606 rigid:2wTqH12DHkSLcixvnxiJPZhqAc0 false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9BY14 uniprotkb:Q16555 intact:EBI-12549378|ensembl:ENSP00000472769|uniprotkb:Q7L5R2|uniprotkb:Q9BPY7 intact:EBI-1104711|uniprotkb:O00424|uniprotkb:D3DSS7|ensembl:ENSP00000309539|uniprotkb:A8K5H2|uniprotkb:B4DR31 psi-mi:tx101_human(display_long)|uniprotkb:TEX101(gene name)|psi-mi:TEX101(display_short)|uniprotkb:Cell surface receptor NYD-SP8(gene name synonym)|uniprotkb:SGRG(gene name synonym)|uniprotkb:Scleroderma-associated autoantigen(gene name synonym)|uniprotkb:Spermatogenesis-related gene protein(gene name synonym)|uniprotkb:UNQ867/PRO1884(orf name) psi-mi:dpyl2_human(display_long)|uniprotkb:DPYSL2(gene name)|psi-mi:DPYSL2(display_short)|uniprotkb:CRMP2(gene name synonym)|uniprotkb:Collapsin response mediator protein 2(gene name synonym)|uniprotkb:N2A3(gene name synonym)|uniprotkb:ULIP2(gene name synonym)|uniprotkb:Unc-33-like phosphoprotein 2(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Schiza et al. (2018) imex:IM-28077|pubmed:30097533 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-25504841|imex:IM-28077-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000131126(gene)|ensembl:ENST00000598265(transcript)|go:"GO:0001669"(acrosomal vesicle)|go:"GO:0002080"(acrosomal membrane)|go:"GO:0005576"(extracellular region)|go:"GO:0005886"(plasma membrane)|go:"GO:0007339"(binding of sperm to zona pellucida)|go:"GO:0009566"(fertilization)|go:"GO:0030317"(flagellated sperm motility)|go:"GO:0044853"(plasma membrane raft)|go:"GO:0046658"(anchored component of plasma membrane)|go:"GO:1901317"(regulation of flagellated sperm motility)|interpro:IPR016054(Ly-6 antigen / uPA receptor -like)|rcsb pdb:7BPR|reactome:R-HSA-163125|refseq:NP_001123483.1|refseq:NP_113639.4 interpro:IPR011778(D-hydantoinase)|interpro:IPR030615|interpro:IPR032466|mint:Q16555|rcsb pdb:2GSE|rcsb pdb:2VM8|rcsb pdb:5LXX|rcsb pdb:5MKV|rcsb pdb:5MLE|rcsb pdb:5X1A|rcsb pdb:5X1C|rcsb pdb:5X1D|rcsb pdb:5YZ5|rcsb pdb:5YZA|rcsb pdb:5YZB|rcsb pdb:6JV9|rcsb pdb:6JVB|reactome:R-HSA-399956|reactome:R-HSA-437239|ensembl:ENSG00000092964(gene)|ensembl:ENST00000311151(transcript)|go:"GO:0004157"(dihydropyrimidinase activity)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005886"(plasma membrane)|go:"GO:0006139"(nucleobase-containing compound metabolic process)|go:"GO:0006897"(endocytosis)|go:"GO:0007010"(cytoskeleton organization)|go:"GO:0007165"(signal transduction)|go:"GO:0007399"(nervous system development)|go:"GO:0007411"(axon guidance)|go:"GO:0007420"(brain development)|go:"GO:0008017"(microtubule binding)|go:"GO:0030516"(regulation of axon extension)|go:"GO:0042802"(identical protein binding)|go:"GO:0045664"(regulation of neuron differentiation)|go:"GO:0070062"(extracellular exosome)|interpro:IPR006680(Amidohydrolase 1)|interpro:IPR011059(Metal-dependent hydrolase, composite)|refseq:NP_001377.1|refseq:NP_001184222.1|refseq:NP_001231533.1 - - - figure legend:Supp Table S4 and Supp Fig. S3|comment:"Coimmunoprecipitation with 34ED229 (T2) anti-TEX101 antibody"|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-testis)|taxid:9606(Homo sapiens) - 2020/03/24 2020/06/18 rogid:ZE4tXTFi7lUCcIbCL4KHzY3a6xM9606 rogid:K5Od8xfnpUzIOy9u6Xbzg4UEN449606 rigid:2wTqH12DHkSLcixvnxiJPZhqAc0 false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9BY14 uniprotkb:P16444 intact:EBI-12549378|ensembl:ENSP00000472769|uniprotkb:Q7L5R2|uniprotkb:Q9BPY7 intact:EBI-749514|uniprotkb:Q96AK2|uniprotkb:D3DX80|ensembl:ENSP00000261615|ensembl:ENSP00000376807|ensembl:ENSP00000397313 psi-mi:tx101_human(display_long)|uniprotkb:TEX101(gene name)|psi-mi:TEX101(display_short)|uniprotkb:Cell surface receptor NYD-SP8(gene name synonym)|uniprotkb:SGRG(gene name synonym)|uniprotkb:Scleroderma-associated autoantigen(gene name synonym)|uniprotkb:Spermatogenesis-related gene protein(gene name synonym)|uniprotkb:UNQ867/PRO1884(orf name) psi-mi:dpep1_human(display_long)|uniprotkb:Microsomal dipeptidase(gene name synonym)|uniprotkb:Renal dipeptidase(gene name synonym)|uniprotkb:Dehydropeptidase-I(gene name synonym)|uniprotkb:DPEP1(gene name)|psi-mi:DPEP1(display_short)|uniprotkb:MDP(gene name synonym)|uniprotkb:RDP(gene name synonym)|uniprotkb:Beta-lactamase(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Schiza et al. (2018) imex:IM-28077|pubmed:30097533 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-25504841|imex:IM-28077-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000131126(gene)|ensembl:ENST00000598265(transcript)|go:"GO:0001669"(acrosomal vesicle)|go:"GO:0002080"(acrosomal membrane)|go:"GO:0005576"(extracellular region)|go:"GO:0005886"(plasma membrane)|go:"GO:0007339"(binding of sperm to zona pellucida)|go:"GO:0009566"(fertilization)|go:"GO:0030317"(flagellated sperm motility)|go:"GO:0044853"(plasma membrane raft)|go:"GO:0046658"(anchored component of plasma membrane)|go:"GO:1901317"(regulation of flagellated sperm motility)|interpro:IPR016054(Ly-6 antigen / uPA receptor -like)|rcsb pdb:7BPR|reactome:R-HSA-163125|refseq:NP_001123483.1|refseq:NP_113639.4 refseq:NP_001121613.1|refseq:NP_004404.1|refseq:XP_011521227.1|refseq:XP_005256342.1|refseq:XP_005256343.1|ensembl:ENSG00000015413(gene)|ensembl:ENST00000261615(transcript)|ensembl:ENST00000393092(transcript)|ensembl:ENST00000421184(transcript)|go:"GO:0005615"(extracellular space)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0006629"(lipid metabolic process)|go:"GO:0006691"(leukotriene metabolic process)|go:"GO:0006749"(glutathione metabolic process)|go:"GO:0006751"(glutathione catabolic process)|go:"GO:0006954"(inflammatory response)|go:"GO:0008235"(metalloexopeptidase activity)|go:"GO:0008270"(zinc ion binding)|go:"GO:0008800"(beta-lactamase activity)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0016999"(antibiotic metabolic process)|go:"GO:0030054"(cell junction)|go:"GO:0030336"(negative regulation of cell migration)|go:"GO:0030593"(neutrophil chemotaxis)|go:"GO:0031225"(anchored component of membrane)|go:"GO:0031528"(microvillus membrane)|go:"GO:0034235"(GPI anchor binding)|go:"GO:0035690"|go:"GO:0043027"(cysteine-type endopeptidase inhibitor activity involved in apoptotic process)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043154"(negative regulation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0045177"(apical part of cell)|go:"GO:0050667"(homocysteine metabolic process)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070573"(metallodipeptidase activity)|go:"GO:0071277"(cellular response to calcium ion)|go:"GO:0071732"(cellular response to nitric oxide)|go:"GO:0072340"(cellular lactam catabolic process)|go:"GO:0072341"(modified amino acid binding)|interpro:IPR000180(Peptidase M19, renal dipeptidase, active site)|interpro:IPR008257(Peptidase M19, renal dipeptidase)|interpro:IPR028536|interpro:IPR032466|rcsb pdb:1ITQ|rcsb pdb:1ITU|reactome:R-HSA-2142691|reactome:R-HSA-5423646|reactome:R-HSA-9664535 - - - figure legend:Supp Table S4 and Supp Fig. S3|comment:"Coimmunoprecipitation with 34ED229 (T2) anti-TEX101 antibody"|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-testis)|taxid:9606(Homo sapiens) - 2020/03/24 2020/06/18 rogid:ZE4tXTFi7lUCcIbCL4KHzY3a6xM9606 rogid:T2UzGo6JLAuXJHoywcc76WDjsJo9606 rigid:2wTqH12DHkSLcixvnxiJPZhqAc0 false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9BY14 uniprotkb:P53618 intact:EBI-12549378|ensembl:ENSP00000472769|uniprotkb:Q7L5R2|uniprotkb:Q9BPY7 intact:EBI-359063|uniprotkb:Q6GTT7|uniprotkb:Q9NTK2|uniprotkb:Q9UNW7|uniprotkb:D3DQX0|ensembl:ENSP00000249923|ensembl:ENSP00000397873 psi-mi:tx101_human(display_long)|uniprotkb:TEX101(gene name)|psi-mi:TEX101(display_short)|uniprotkb:Cell surface receptor NYD-SP8(gene name synonym)|uniprotkb:SGRG(gene name synonym)|uniprotkb:Scleroderma-associated autoantigen(gene name synonym)|uniprotkb:Spermatogenesis-related gene protein(gene name synonym)|uniprotkb:UNQ867/PRO1884(orf name) psi-mi:copb_human(display_long)|uniprotkb:COPB1(gene name)|psi-mi:COPB1(display_short)|uniprotkb:COPB(gene name synonym)|uniprotkb:MSTP026(orf name)|uniprotkb:Beta-coat protein(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Schiza et al. (2018) imex:IM-28077|pubmed:30097533 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-25504841|imex:IM-28077-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000131126(gene)|ensembl:ENST00000598265(transcript)|go:"GO:0001669"(acrosomal vesicle)|go:"GO:0002080"(acrosomal membrane)|go:"GO:0005576"(extracellular region)|go:"GO:0005886"(plasma membrane)|go:"GO:0007339"(binding of sperm to zona pellucida)|go:"GO:0009566"(fertilization)|go:"GO:0030317"(flagellated sperm motility)|go:"GO:0044853"(plasma membrane raft)|go:"GO:0046658"(anchored component of plasma membrane)|go:"GO:1901317"(regulation of flagellated sperm motility)|interpro:IPR016054(Ly-6 antigen / uPA receptor -like)|rcsb pdb:7BPR|reactome:R-HSA-163125|refseq:NP_001123483.1|refseq:NP_113639.4 refseq:NP_001137533.1|refseq:NP_001137534.1|refseq:NP_057535.1|ensembl:ENSG00000129083(gene)|ensembl:ENST00000249923(transcript)|ensembl:ENST00000439561(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005793"(endoplasmic reticulum-Golgi intermediate compartment)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005798"(Golgi-associated vesicle)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0006891"(intra-Golgi vesicle-mediated transport)|go:"GO:0016020"(membrane)|go:"GO:0030126"(COPI vesicle coat)|go:"GO:0030133"(transport vesicle)|go:"GO:0030667"(secretory granule membrane)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0070821"(tertiary granule membrane)|go:"GO:0101003"(ficolin-1-rich granule membrane)|interpro:IPR002553(Clathrin/coatomer adaptor, adaptin-like, N-terminal)|interpro:IPR011710(Coatomer, beta subunit, C-terminal)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR016460(Coatomer, beta subunit)|interpro:IPR029446|mint:P53618|reactome:R-HSA-6798695|reactome:R-HSA-6807878|reactome:R-HSA-6811434|dip:DIP-265N - - - figure legend:Supp Table S4 and Supp Fig. S3|comment:"Coimmunoprecipitation with 34ED229 (T2) anti-TEX101 antibody"|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-testis)|taxid:9606(Homo sapiens) - 2020/03/24 2020/06/18 rogid:ZE4tXTFi7lUCcIbCL4KHzY3a6xM9606 rogid:EBxh2JlK3Z8HxbZXa3fG0nOgYu89606 rigid:2wTqH12DHkSLcixvnxiJPZhqAc0 false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9BY14 uniprotkb:P62879 intact:EBI-12549378|ensembl:ENSP00000472769|uniprotkb:Q7L5R2|uniprotkb:Q9BPY7 intact:EBI-356942|uniprotkb:P54312|uniprotkb:P11016|uniprotkb:B3KPU1|ensembl:ENSP00000305260|ensembl:ENSP00000377501|ensembl:ENSP00000377503 psi-mi:tx101_human(display_long)|uniprotkb:TEX101(gene name)|psi-mi:TEX101(display_short)|uniprotkb:Cell surface receptor NYD-SP8(gene name synonym)|uniprotkb:SGRG(gene name synonym)|uniprotkb:Scleroderma-associated autoantigen(gene name synonym)|uniprotkb:Spermatogenesis-related gene protein(gene name synonym)|uniprotkb:UNQ867/PRO1884(orf name) psi-mi:gbb2_human(display_long)|uniprotkb:GNB2(gene name)|psi-mi:GNB2(display_short)|uniprotkb:Transducin beta chain 2(gene name synonym)|uniprotkb:G protein subunit beta-2(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Schiza et al. (2018) imex:IM-28077|pubmed:30097533 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-25504841|imex:IM-28077-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000131126(gene)|ensembl:ENST00000598265(transcript)|go:"GO:0001669"(acrosomal vesicle)|go:"GO:0002080"(acrosomal membrane)|go:"GO:0005576"(extracellular region)|go:"GO:0005886"(plasma membrane)|go:"GO:0007339"(binding of sperm to zona pellucida)|go:"GO:0009566"(fertilization)|go:"GO:0030317"(flagellated sperm motility)|go:"GO:0044853"(plasma membrane raft)|go:"GO:0046658"(anchored component of plasma membrane)|go:"GO:1901317"(regulation of flagellated sperm motility)|interpro:IPR016054(Ly-6 antigen / uPA receptor -like)|rcsb pdb:7BPR|reactome:R-HSA-163125|refseq:NP_001123483.1|refseq:NP_113639.4 refseq:NP_005264.2|go:"GO:0031682"(G-protein gamma-subunit binding)|go:"GO:0031982"(vesicle)|go:"GO:0044297"(cell body)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051020"(GTPase binding)|go:"GO:0070062"(extracellular exosome)|interpro:IPR001632(G-protein, beta subunit)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR016346(Guanine nucleotide-binding protein, beta subunit)|interpro:IPR019775|interpro:IPR020472|interpro:IPR036322|mint:P62879|reactome:R-HSA-1296041|reactome:R-HSA-163359|reactome:R-HSA-202040|reactome:R-HSA-381676|reactome:R-HSA-392170|reactome:R-HSA-392451|reactome:R-HSA-392851|reactome:R-HSA-400042|reactome:R-HSA-4086398|reactome:R-HSA-416476|reactome:R-HSA-416482|reactome:R-HSA-418217|reactome:R-HSA-418555|reactome:R-HSA-418592|reactome:R-HSA-418594|reactome:R-HSA-418597|reactome:R-HSA-420092|reactome:R-HSA-428930|reactome:R-HSA-432040|reactome:R-HSA-456926|reactome:R-HSA-500657|reactome:R-HSA-6814122|reactome:R-HSA-8964315|reactome:R-HSA-8964616|reactome:R-HSA-9009391|reactome:R-HSA-9660821|reactome:R-HSA-997272|go:"GO:0016020"(membrane)|ensembl:ENSG00000172354(gene)|ensembl:ENST00000303210(transcript)|ensembl:ENST00000393924(transcript)|ensembl:ENST00000393926(transcript)|go:"GO:0003924"(GTPase activity)|go:"GO:0005246"(calcium channel regulator activity)|go:"GO:0005615"(extracellular space)|go:"GO:0005737"(cytoplasm)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005829"(cytosol)|go:"GO:0005834"(heterotrimeric G-protein complex)|go:"GO:0005925"(focal adhesion)|go:"GO:0007186"(G protein-coupled receptor signaling pathway) - - - figure legend:Supp Table S4 and Supp Fig. S3|comment:"Coimmunoprecipitation with 34ED229 (T2) anti-TEX101 antibody"|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-testis)|taxid:9606(Homo sapiens) - 2020/03/24 2020/06/18 rogid:ZE4tXTFi7lUCcIbCL4KHzY3a6xM9606 rogid:dingPUxdpAhe7UMLquv0eqXNtUM9606 rigid:2wTqH12DHkSLcixvnxiJPZhqAc0 false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9BY14 uniprotkb:Q13151 intact:EBI-12549378|ensembl:ENSP00000472769|uniprotkb:Q7L5R2|uniprotkb:Q9BPY7 intact:EBI-724092|ensembl:ENSP00000316042|intact:EBI-1043661|uniprotkb:Q6IB18 psi-mi:tx101_human(display_long)|uniprotkb:TEX101(gene name)|psi-mi:TEX101(display_short)|uniprotkb:Cell surface receptor NYD-SP8(gene name synonym)|uniprotkb:SGRG(gene name synonym)|uniprotkb:Scleroderma-associated autoantigen(gene name synonym)|uniprotkb:Spermatogenesis-related gene protein(gene name synonym)|uniprotkb:UNQ867/PRO1884(orf name) psi-mi:roa0_human(display_long)|uniprotkb:HNRPA0(gene name synonym)|uniprotkb:HNRNPA0(gene name)|psi-mi:HNRNPA0(display_short) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Schiza et al. (2018) imex:IM-28077|pubmed:30097533 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-25504841|imex:IM-28077-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000131126(gene)|ensembl:ENST00000598265(transcript)|go:"GO:0001669"(acrosomal vesicle)|go:"GO:0002080"(acrosomal membrane)|go:"GO:0005576"(extracellular region)|go:"GO:0005886"(plasma membrane)|go:"GO:0007339"(binding of sperm to zona pellucida)|go:"GO:0009566"(fertilization)|go:"GO:0030317"(flagellated sperm motility)|go:"GO:0044853"(plasma membrane raft)|go:"GO:0046658"(anchored component of plasma membrane)|go:"GO:1901317"(regulation of flagellated sperm motility)|interpro:IPR016054(Ly-6 antigen / uPA receptor -like)|rcsb pdb:7BPR|reactome:R-HSA-163125|refseq:NP_001123483.1|refseq:NP_113639.4 refseq:NP_006796.1|ensembl:ENSG00000177733(gene)|ensembl:ENST00000314940(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006397"(mRNA processing)|go:"GO:0006954"(inflammatory response)|go:"GO:0019901"(protein kinase binding)|go:"GO:0032496"(response to lipopolysaccharide)|go:"GO:0035925"(mRNA 3'-UTR AU-rich region binding)|go:"GO:0070935"(3'-UTR-mediated mRNA stabilization)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR034801|interpro:IPR035979|mint:Q13151|reactome:R-HSA-72163|reactome:R-HSA-72203 - - - figure legend:Supp Table S4 and Supp Fig. S3|comment:"Coimmunoprecipitation with 34ED229 (T2) anti-TEX101 antibody"|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-testis)|taxid:9606(Homo sapiens) - 2020/03/24 2020/06/18 rogid:ZE4tXTFi7lUCcIbCL4KHzY3a6xM9606 rogid:buyQxR8FLxd4N6jRhwVsroeGrBw9606 rigid:2wTqH12DHkSLcixvnxiJPZhqAc0 false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9BY14 uniprotkb:P43686 intact:EBI-12549378|ensembl:ENSP00000472769|uniprotkb:Q7L5R2|uniprotkb:Q9BPY7 intact:EBI-743997|uniprotkb:Q96FV5|uniprotkb:Q9UBM3|uniprotkb:Q9UEX3|ensembl:ENSP00000157812|ensembl:ENSP00000487367 psi-mi:tx101_human(display_long)|uniprotkb:TEX101(gene name)|psi-mi:TEX101(display_short)|uniprotkb:Cell surface receptor NYD-SP8(gene name synonym)|uniprotkb:SGRG(gene name synonym)|uniprotkb:Scleroderma-associated autoantigen(gene name synonym)|uniprotkb:Spermatogenesis-related gene protein(gene name synonym)|uniprotkb:UNQ867/PRO1884(orf name) psi-mi:prs6b_human(display_long)|uniprotkb:Proteasome 26S subunit ATPase 4(gene name synonym)|uniprotkb:MB67-interacting protein(gene name synonym)|uniprotkb:PSMC4(gene name)|psi-mi:PSMC4(display_short)|uniprotkb:TBP7(gene name synonym)|uniprotkb:MIP224(gene name synonym)|uniprotkb:Tat-binding protein 7(gene name synonym)|uniprotkb:26S proteasome AAA-ATPase subunit RPT3(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Schiza et al. (2018) imex:IM-28077|pubmed:30097533 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-25504841|imex:IM-28077-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000131126(gene)|ensembl:ENST00000598265(transcript)|go:"GO:0001669"(acrosomal vesicle)|go:"GO:0002080"(acrosomal membrane)|go:"GO:0005576"(extracellular region)|go:"GO:0005886"(plasma membrane)|go:"GO:0007339"(binding of sperm to zona pellucida)|go:"GO:0009566"(fertilization)|go:"GO:0030317"(flagellated sperm motility)|go:"GO:0044853"(plasma membrane raft)|go:"GO:0046658"(anchored component of plasma membrane)|go:"GO:1901317"(regulation of flagellated sperm motility)|interpro:IPR016054(Ly-6 antigen / uPA receptor -like)|rcsb pdb:7BPR|reactome:R-HSA-163125|refseq:NP_001123483.1|refseq:NP_113639.4 refseq:NP_006494.1|refseq:NP_694546.1|dip:DIP-29274N|ensembl:ENSG00000013275(gene)|ensembl:ENSG00000281221(gene)|ensembl:ENST00000157812(transcript)|ensembl:ENST00000629691(transcript)|go:"GO:0000502"(proteasome complex)|go:"GO:0001824"(blastocyst development)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006508"(proteolysis)|go:"GO:0008540"(proteasome regulatory particle, base subcomplex)|go:"GO:0016020"(membrane)|go:"GO:0016234"(inclusion body)|go:"GO:0016887"(ATP hydrolysis activity)|go:"GO:0022624"(proteasome accessory complex)|go:"GO:0030163"(protein catabolic process)|go:"GO:0031597"(cytosolic proteasome complex)|go:"GO:0036402"(proteasome-activating activity)|go:"GO:0045202"(synapse)|go:"GO:0045899"(positive regulation of RNA polymerase II transcription preinitiation complex assembly)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR003959(AAA ATPase, core)|interpro:IPR003960(AAA ATPase, conserved site)|interpro:IPR005937(26S proteasome subunit P45)|interpro:IPR027417|interpro:IPR032501|interpro:IPR035256|interpro:IPR041569|mint:P43686|rcsb pdb:2DVW|rcsb pdb:5GJQ|rcsb pdb:5GJR|rcsb pdb:5L4G|rcsb pdb:5LN3|rcsb pdb:5M32|rcsb pdb:5T0C|rcsb pdb:5T0G|rcsb pdb:5T0H|rcsb pdb:5T0I|rcsb pdb:5T0J|rcsb pdb:5VFP|rcsb pdb:5VFQ|rcsb pdb:5VFR|rcsb pdb:5VFS|rcsb pdb:5VFT|rcsb pdb:5VFU|rcsb pdb:5VGZ|rcsb pdb:5VHF|rcsb pdb:5VHH|rcsb pdb:5VHI|rcsb pdb:5VHJ|rcsb pdb:5VHM|rcsb pdb:5VHN|rcsb pdb:5VHO|rcsb pdb:5VHP|rcsb pdb:5VHQ|rcsb pdb:5VHR|rcsb pdb:5VHS|rcsb pdb:6MSB|rcsb pdb:6MSD|rcsb pdb:6MSE|rcsb pdb:6MSG|rcsb pdb:6MSH|rcsb pdb:6MSJ|rcsb pdb:6MSK|rcsb pdb:6WJD|rcsb pdb:6WJN|reactome:R-HSA-1169091|reactome:R-HSA-1234176|reactome:R-HSA-1236974|reactome:R-HSA-1236978|reactome:R-HSA-174084|reactome:R-HSA-174113|reactome:R-HSA-174154|reactome:R-HSA-174178|reactome:R-HSA-174184|reactome:R-HSA-180534|reactome:R-HSA-180585|reactome:R-HSA-187577|reactome:R-HSA-195253|reactome:R-HSA-202424|reactome:R-HSA-211733|reactome:R-HSA-2467813|reactome:R-HSA-2871837|reactome:R-HSA-349425|reactome:R-HSA-350562|reactome:R-HSA-382556|reactome:R-HSA-450408|reactome:R-HSA-4608870|reactome:R-HSA-4641257|reactome:R-HSA-4641258|reactome:R-HSA-5358346|reactome:R-HSA-5362768|reactome:R-HSA-5607761|reactome:R-HSA-5607764|reactome:R-HSA-5610780|reactome:R-HSA-5610783|reactome:R-HSA-5610785|reactome:R-HSA-5632684|reactome:R-HSA-5658442|reactome:R-HSA-5668541|reactome:R-HSA-5676590|reactome:R-HSA-5678895|reactome:R-HSA-5687128|reactome:R-HSA-5689603|reactome:R-HSA-5689880|reactome:R-HSA-68827|reactome:R-HSA-68949|reactome:R-HSA-69017|reactome:R-HSA-69481|reactome:R-HSA-75815|reactome:R-HSA-8852276|reactome:R-HSA-8854050|reactome:R-HSA-8932339|reactome:R-HSA-8939236|reactome:R-HSA-8939902|reactome:R-HSA-8941858|reactome:R-HSA-8948751|reactome:R-HSA-8951664|reactome:R-HSA-9010553|reactome:R-HSA-9020702|reactome:R-HSA-9604323|reactome:R-HSA-983168|reactome:R-HSA-69601 - - - figure legend:Supp Table S4 and Supp Fig. S3|comment:"Coimmunoprecipitation with 34ED229 (T2) anti-TEX101 antibody"|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-testis)|taxid:9606(Homo sapiens) - 2020/03/24 2020/06/18 rogid:ZE4tXTFi7lUCcIbCL4KHzY3a6xM9606 rogid:ZwHUFX8vJa8IPZi000dHiFtUtlM9606 rigid:2wTqH12DHkSLcixvnxiJPZhqAc0 false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9BY14 uniprotkb:Q08722 intact:EBI-12549378|ensembl:ENSP00000472769|uniprotkb:Q7L5R2|uniprotkb:Q9BPY7 intact:EBI-1268321|uniprotkb:Q53Y71|uniprotkb:Q96A60|uniprotkb:A8K198|uniprotkb:D3DN59|ensembl:ENSP00000355361 psi-mi:tx101_human(display_long)|uniprotkb:TEX101(gene name)|psi-mi:TEX101(display_short)|uniprotkb:Cell surface receptor NYD-SP8(gene name synonym)|uniprotkb:SGRG(gene name synonym)|uniprotkb:Scleroderma-associated autoantigen(gene name synonym)|uniprotkb:Spermatogenesis-related gene protein(gene name synonym)|uniprotkb:UNQ867/PRO1884(orf name) psi-mi:cd47_human(display_long)|uniprotkb:CD47(gene name)|psi-mi:CD47(display_short)|uniprotkb:MER6(gene name synonym)|uniprotkb:Integrin-associated protein(gene name synonym)|uniprotkb:Antigenic surface determinant protein OA3(gene name synonym)|uniprotkb:Protein MER6(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Schiza et al. (2018) imex:IM-28077|pubmed:30097533 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-25504841|imex:IM-28077-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000131126(gene)|ensembl:ENST00000598265(transcript)|go:"GO:0001669"(acrosomal vesicle)|go:"GO:0002080"(acrosomal membrane)|go:"GO:0005576"(extracellular region)|go:"GO:0005886"(plasma membrane)|go:"GO:0007339"(binding of sperm to zona pellucida)|go:"GO:0009566"(fertilization)|go:"GO:0030317"(flagellated sperm motility)|go:"GO:0044853"(plasma membrane raft)|go:"GO:0046658"(anchored component of plasma membrane)|go:"GO:1901317"(regulation of flagellated sperm motility)|interpro:IPR016054(Ly-6 antigen / uPA receptor -like)|rcsb pdb:7BPR|reactome:R-HSA-163125|refseq:NP_001123483.1|refseq:NP_113639.4 refseq:NP_001768.1|refseq:NP_942088.1|dip:DIP-39948N|ensembl:ENSG00000196776(gene)|ensembl:ENST00000361309(transcript)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0009986"(cell surface)|go:"GO:0016477"(cell migration)|go:"GO:0022409"(positive regulation of cell-cell adhesion)|go:"GO:0032649"(regulation of interferon-gamma production)|go:"GO:0032653"(regulation of interleukin-10 production)|go:"GO:0032655"(regulation of interleukin-12 production)|go:"GO:0032675"(regulation of interleukin-6 production)|go:"GO:0032680"(regulation of tumor necrosis factor production)|go:"GO:0035579"(specific granule membrane)|go:"GO:0045428"(regulation of nitric oxide biosynthetic process)|go:"GO:0050729"(positive regulation of inflammatory response)|go:"GO:0050766"(positive regulation of phagocytosis)|go:"GO:0050870"(positive regulation of T cell activation)|go:"GO:0051496"(positive regulation of stress fiber assembly)|go:"GO:0070053"(thrombospondin receptor activity)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070821"(tertiary granule membrane)|go:"GO:0071346"(cellular response to interferon-gamma)|go:"GO:0071347"(cellular response to interleukin-1)|go:"GO:0071349"(cellular response to interleukin-12)|go:"GO:0086080"(protein binding involved in heterotypic cell-cell adhesion)|go:"GO:0098632"(cell-cell adhesion mediator activity)|go:"GO:1904669"(ATP export)|go:"GO:0007229"(integrin-mediated signaling pathway)|go:"GO:2000439"(positive regulation of monocyte extravasation)|interpro:IPR006704(CD47 integrin associated protein)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR013147(CD47 transmembrane)|interpro:IPR013270(CD47 immunoglobulin-like)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR036179|interpro:IPR037805|rcsb pdb:2JJS|rcsb pdb:2JJT|rcsb pdb:2VSC|rcsb pdb:4CMM|rcsb pdb:4KJY|rcsb pdb:5IWL|rcsb pdb:5TZ2|rcsb pdb:5TZT|rcsb pdb:5TZU|reactome:R-HSA-202733|reactome:R-HSA-216083|reactome:R-HSA-391160|reactome:R-HSA-6798695|go:"GO:1905450"(negative regulation of Fc-gamma receptor signaling pathway involved in phagocytosis) - - - figure legend:Supp Table S4 and Supp Fig. S3|comment:"Coimmunoprecipitation with 34ED229 (T2) anti-TEX101 antibody"|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-testis)|taxid:9606(Homo sapiens) - 2020/03/24 2020/06/18 rogid:ZE4tXTFi7lUCcIbCL4KHzY3a6xM9606 rogid:2hhmwvfeDFe7KHXzsBOJkjo2pjk9606 rigid:2wTqH12DHkSLcixvnxiJPZhqAc0 false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9BY14 uniprotkb:P62195 intact:EBI-12549378|ensembl:ENSP00000472769|uniprotkb:Q7L5R2|uniprotkb:Q9BPY7 intact:EBI-357745|uniprotkb:O35051|uniprotkb:O43208|uniprotkb:P52915|uniprotkb:P47210|uniprotkb:P52916|uniprotkb:A8K763|uniprotkb:A8K3Z3|ensembl:ENSP00000310572 psi-mi:tx101_human(display_long)|uniprotkb:TEX101(gene name)|psi-mi:TEX101(display_short)|uniprotkb:Cell surface receptor NYD-SP8(gene name synonym)|uniprotkb:SGRG(gene name synonym)|uniprotkb:Scleroderma-associated autoantigen(gene name synonym)|uniprotkb:Spermatogenesis-related gene protein(gene name synonym)|uniprotkb:UNQ867/PRO1884(orf name) psi-mi:prs8_human(display_long)|uniprotkb:PSMC5(gene name)|psi-mi:PSMC5(display_short)|uniprotkb:SUG1(gene name synonym)|uniprotkb:Proteasome 26S subunit ATPase 5(gene name synonym)|uniprotkb:Proteasome subunit p45(gene name synonym)|uniprotkb:p45/SUG(gene name synonym)|uniprotkb:Thyroid hormone receptor-interacting protein 1(gene name synonym)|uniprotkb:26S proteasome AAA-ATPase subunit RPT6(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Schiza et al. (2018) imex:IM-28077|pubmed:30097533 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-25504841|imex:IM-28077-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000131126(gene)|ensembl:ENST00000598265(transcript)|go:"GO:0001669"(acrosomal vesicle)|go:"GO:0002080"(acrosomal membrane)|go:"GO:0005576"(extracellular region)|go:"GO:0005886"(plasma membrane)|go:"GO:0007339"(binding of sperm to zona pellucida)|go:"GO:0009566"(fertilization)|go:"GO:0030317"(flagellated sperm motility)|go:"GO:0044853"(plasma membrane raft)|go:"GO:0046658"(anchored component of plasma membrane)|go:"GO:1901317"(regulation of flagellated sperm motility)|interpro:IPR016054(Ly-6 antigen / uPA receptor -like)|rcsb pdb:7BPR|reactome:R-HSA-163125|refseq:NP_001123483.1|refseq:NP_113639.4 refseq:NP_001186092.1|refseq:NP_002796.4|reactome:R-HSA-195253|ensembl:ENSG00000087191(gene)|ensembl:ENST00000310144(transcript)|go:"GO:0000502"(proteasome complex)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0008134"(transcription factor binding)|go:"GO:0008540"(proteasome regulatory particle, base subcomplex)|go:"GO:0016020"(membrane)|go:"GO:0016234"(inclusion body)|go:"GO:0017025"(TBP-class protein binding)|go:"GO:0022624"(proteasome accessory complex)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0031531"(thyrotropin-releasing hormone receptor binding)|go:"GO:0031595"(nuclear proteasome complex)|go:"GO:0031597"(cytosolic proteasome complex)|go:"GO:0036402"(proteasome-activating activity)|go:"GO:0043069"(negative regulation of programmed cell death)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045899"(positive regulation of RNA polymerase II transcription preinitiation complex assembly)|go:"GO:0050804"(modulation of chemical synaptic transmission)|go:"GO:0070062"(extracellular exosome)|go:"GO:0072562"(blood microparticle)|go:"GO:0090261"(positive regulation of inclusion body assembly)|go:"GO:0098794"(postsynapse)|go:"GO:0140296"(general transcription initiation factor binding)|go:"GO:0140297"(DNA-binding transcription factor binding)|go:"GO:1901800"(positive regulation of proteasomal protein catabolic process)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR003959(AAA ATPase, core)|interpro:IPR003960(AAA ATPase, conserved site)|interpro:IPR005937(26S proteasome subunit P45)|interpro:IPR027417|interpro:IPR032501|interpro:IPR041569|mint:P62195|rcsb pdb:2KRK|rcsb pdb:3KW6|rcsb pdb:5GJQ|rcsb pdb:5GJR|rcsb pdb:5L4G|rcsb pdb:5LN3|rcsb pdb:5M32|rcsb pdb:5T0C|rcsb pdb:5T0G|rcsb pdb:5T0H|rcsb pdb:5T0I|rcsb pdb:5T0J|rcsb pdb:5VFP|rcsb pdb:5VFQ|rcsb pdb:5VFR|rcsb pdb:5VFS|rcsb pdb:5VFT|rcsb pdb:5VFU|rcsb pdb:5VGZ|rcsb pdb:5VHF|rcsb pdb:5VHH|rcsb pdb:5VHI|rcsb pdb:5VHJ|rcsb pdb:5VHM|rcsb pdb:5VHN|rcsb pdb:5VHO|rcsb pdb:5VHP|rcsb pdb:5VHQ|rcsb pdb:5VHR|rcsb pdb:5VHS|rcsb pdb:6MSB|rcsb pdb:6MSD|rcsb pdb:6MSG|rcsb pdb:6MSH|rcsb pdb:6MSJ|rcsb pdb:6MSK|rcsb pdb:6WJD|rcsb pdb:6WJN|reactome:R-HSA-1169091|reactome:R-HSA-1234176|reactome:R-HSA-1236974|reactome:R-HSA-1236978|reactome:R-HSA-174084|reactome:R-HSA-174113|reactome:R-HSA-174154|reactome:R-HSA-174178|reactome:R-HSA-174184|reactome:R-HSA-180534|reactome:R-HSA-180585|reactome:R-HSA-187577|reactome:R-HSA-202424|reactome:R-HSA-211733|reactome:R-HSA-2467813|reactome:R-HSA-2871837|reactome:R-HSA-349425|reactome:R-HSA-350562|reactome:R-HSA-382556|reactome:R-HSA-450408|reactome:R-HSA-4608870|reactome:R-HSA-4641257|reactome:R-HSA-4641258|reactome:R-HSA-5358346|reactome:R-HSA-5362768|reactome:R-HSA-5607761|reactome:R-HSA-5607764|reactome:R-HSA-5610780|reactome:R-HSA-5610783|reactome:R-HSA-5610785|reactome:R-HSA-5632684|reactome:R-HSA-5658442|reactome:R-HSA-5668541|reactome:R-HSA-5676590|reactome:R-HSA-5678895|reactome:R-HSA-5687128|reactome:R-HSA-5689603|reactome:R-HSA-5689880|reactome:R-HSA-68827|reactome:R-HSA-68949|reactome:R-HSA-69017|reactome:R-HSA-69481|reactome:R-HSA-69601|reactome:R-HSA-75815|reactome:R-HSA-8852276|reactome:R-HSA-8854050|reactome:R-HSA-8932339|reactome:R-HSA-8939236|reactome:R-HSA-8939902|reactome:R-HSA-8941858|reactome:R-HSA-8948751|reactome:R-HSA-8951664|reactome:R-HSA-9010553|reactome:R-HSA-9020702|reactome:R-HSA-9604323|reactome:R-HSA-983168|dip:DIP-36645N - - crc64:29C6410C4A85A7F7 figure legend:Supp Table S4 and Supp Fig. S3|comment:"Coimmunoprecipitation with 34ED229 (T2) anti-TEX101 antibody"|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-testis)|taxid:9606(Homo sapiens) - 2020/03/24 2020/06/18 rogid:ZE4tXTFi7lUCcIbCL4KHzY3a6xM9606 rogid:zgUTOX/O4m86U/Nf+pnT7u0m0gY9606 rigid:2wTqH12DHkSLcixvnxiJPZhqAc0 false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9BY14 uniprotkb:P24666 intact:EBI-12549378|ensembl:ENSP00000472769|uniprotkb:Q7L5R2|uniprotkb:Q9BPY7 intact:EBI-717701|uniprotkb:P24667|uniprotkb:Q16035|uniprotkb:Q53RU0|uniprotkb:Q16036|uniprotkb:Q16725|uniprotkb:Q3KQX8|uniprotkb:A8K1L9|uniprotkb:B5MCC7|ensembl:ENSP00000272065 psi-mi:tx101_human(display_long)|uniprotkb:TEX101(gene name)|psi-mi:TEX101(display_short)|uniprotkb:Cell surface receptor NYD-SP8(gene name synonym)|uniprotkb:SGRG(gene name synonym)|uniprotkb:Scleroderma-associated autoantigen(gene name synonym)|uniprotkb:Spermatogenesis-related gene protein(gene name synonym)|uniprotkb:UNQ867/PRO1884(orf name) psi-mi:ppac_human(display_long)|uniprotkb:Low molecular weight cytosolic acid phosphatase(gene name synonym)|uniprotkb:Red cell acid phosphatase 1(gene name synonym)|uniprotkb:Adipocyte acid phosphatase(gene name synonym)|uniprotkb:ACP1(gene name)|psi-mi:ACP1(display_short) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Schiza et al. (2018) imex:IM-28077|pubmed:30097533 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-25504841|imex:IM-28077-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000131126(gene)|ensembl:ENST00000598265(transcript)|go:"GO:0001669"(acrosomal vesicle)|go:"GO:0002080"(acrosomal membrane)|go:"GO:0005576"(extracellular region)|go:"GO:0005886"(plasma membrane)|go:"GO:0007339"(binding of sperm to zona pellucida)|go:"GO:0009566"(fertilization)|go:"GO:0030317"(flagellated sperm motility)|go:"GO:0044853"(plasma membrane raft)|go:"GO:0046658"(anchored component of plasma membrane)|go:"GO:1901317"(regulation of flagellated sperm motility)|interpro:IPR016054(Ly-6 antigen / uPA receptor -like)|rcsb pdb:7BPR|reactome:R-HSA-163125|refseq:NP_001123483.1|refseq:NP_113639.4 refseq:NP_004291.1|refseq:NP_009030.1|ensembl:ENSG00000143727(gene)|ensembl:ENST00000272065(transcript)|go:"GO:0003993"(acid phosphatase activity)|go:"GO:0004725"(protein tyrosine phosphatase activity)|go:"GO:0004726"(non-membrane spanning protein tyrosine phosphatase activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0009898"(cytoplasmic side of plasma membrane)|go:"GO:0042383"(sarcolemma)|go:"GO:0070062"(extracellular exosome)|interpro:IPR002115(Protein-tyrosine phosphatase, low molecular weight, mammalian)|interpro:IPR017867|interpro:IPR023485|interpro:IPR036196|mint:P24666|rcsb pdb:1XWW|rcsb pdb:3N8I|rcsb pdb:4Z99|rcsb pdb:4Z9A|rcsb pdb:4Z9B|rcsb pdb:5JNR|rcsb pdb:5JNS|rcsb pdb:5JNT|rcsb pdb:5KQG|rcsb pdb:5KQL|rcsb pdb:5KQM|rcsb pdb:5KQP|rcsb pdb:5PNT|rcsb pdb:6Y2V|rcsb pdb:6Y2W|rcsb pdb:7KH8 - - - figure legend:Supp Table S4 and Supp Fig. S3|comment:"Coimmunoprecipitation with 34ED229 (T2) anti-TEX101 antibody"|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-testis)|taxid:9606(Homo sapiens) - 2020/03/24 2020/06/18 rogid:ZE4tXTFi7lUCcIbCL4KHzY3a6xM9606 rogid:j4VyGaaWO8l/Ah8i1HBU6EnbK289606 rigid:2wTqH12DHkSLcixvnxiJPZhqAc0 false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9BY14 uniprotkb:P36269 intact:EBI-12549378|ensembl:ENSP00000472769|uniprotkb:Q7L5R2|uniprotkb:Q9BPY7 intact:EBI-21840702|uniprotkb:Q53XM9|uniprotkb:Q6GMP0|uniprotkb:Q96FC1|uniprotkb:Q9UFM5|ensembl:ENSP00000330080 psi-mi:tx101_human(display_long)|uniprotkb:TEX101(gene name)|psi-mi:TEX101(display_short)|uniprotkb:Cell surface receptor NYD-SP8(gene name synonym)|uniprotkb:SGRG(gene name synonym)|uniprotkb:Scleroderma-associated autoantigen(gene name synonym)|uniprotkb:Spermatogenesis-related gene protein(gene name synonym)|uniprotkb:UNQ867/PRO1884(orf name) psi-mi:ggt5_human(display_long)|uniprotkb:Gamma-glutamyl transpeptidase-related enzyme(gene name synonym)|uniprotkb:Gamma-glutamyltransferase 5(gene name synonym)|uniprotkb:Gamma-glutamyltransferase-like activity 1(gene name synonym)|uniprotkb:Gamma-glutamyltranspeptidase 5(gene name synonym)|uniprotkb:Leukotriene-C4 hydrolase(gene name synonym)|uniprotkb:GGT5(gene name)|psi-mi:GGT5(display_short)|uniprotkb:GGTLA1(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Schiza et al. (2018) imex:IM-28077|pubmed:30097533 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-25504841|imex:IM-28077-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000131126(gene)|ensembl:ENST00000598265(transcript)|go:"GO:0001669"(acrosomal vesicle)|go:"GO:0002080"(acrosomal membrane)|go:"GO:0005576"(extracellular region)|go:"GO:0005886"(plasma membrane)|go:"GO:0007339"(binding of sperm to zona pellucida)|go:"GO:0009566"(fertilization)|go:"GO:0030317"(flagellated sperm motility)|go:"GO:0044853"(plasma membrane raft)|go:"GO:0046658"(anchored component of plasma membrane)|go:"GO:1901317"(regulation of flagellated sperm motility)|interpro:IPR016054(Ly-6 antigen / uPA receptor -like)|rcsb pdb:7BPR|reactome:R-HSA-163125|refseq:NP_001123483.1|refseq:NP_113639.4 refseq:NP_001093251.1|refseq:NP_001093252.1|refseq:NP_001289393.1|refseq:NP_001289394.1|refseq:NP_004112.2|interpro:IPR000101(Gamma-glutamyltranspeptidase)|interpro:IPR029055|interpro:IPR043137|interpro:IPR043138|reactome:R-HSA-174403|reactome:R-HSA-2142691|reactome:R-HSA-5423646|reactome:R-HSA-9664535|ensembl:ENSG00000099998(gene)|ensembl:ENST00000327365(transcript)|go:"GO:0000048"(peptidyltransferase activity)|go:"GO:0002951"("leukotriene-C(4) hydrolase")|go:"GO:0005886"(plasma membrane)|go:"GO:0006508"(proteolysis)|go:"GO:0006520"(cellular amino acid metabolic process)|go:"GO:0006631"(fatty acid metabolic process)|go:"GO:0006750"(glutathione biosynthetic process)|go:"GO:0006751"(glutathione catabolic process)|go:"GO:0006954"(inflammatory response)|go:"GO:0007283"(spermatogenesis)|go:"GO:0016021"(integral component of membrane)|go:"GO:0031226"(intrinsic component of plasma membrane)|go:"GO:0032355"(response to estradiol)|go:"GO:0032496"(response to lipopolysaccharide)|go:"GO:0034612"(response to tumor necrosis factor)|go:"GO:0036374"(glutathione hydrolase activity)|go:"GO:0102953"(hypoglycin A gamma-glutamyl transpeptidase activity)|go:"GO:0103068"(leukotriene C4 gamma-glutamyl transferase activity)|go:"GO:1901750"(leukotriene D4 biosynthetic process) - - - figure legend:Supp Table S4 and Supp Fig. S3|comment:"Coimmunoprecipitation with 34ED229 (T2) anti-TEX101 antibody"|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-testis)|taxid:9606(Homo sapiens) - 2020/03/24 2020/06/18 rogid:ZE4tXTFi7lUCcIbCL4KHzY3a6xM9606 rogid:LeWzl5QO2lB4ojhExlTXH8yE/2U9606 rigid:2wTqH12DHkSLcixvnxiJPZhqAc0 false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9BY14 uniprotkb:P31323 intact:EBI-12549378|ensembl:ENSP00000472769|uniprotkb:Q7L5R2|uniprotkb:Q9BPY7 intact:EBI-2930670|ensembl:ENSP00000265717|ensembl:ENSP00000491687|uniprotkb:A4D0R9 psi-mi:tx101_human(display_long)|uniprotkb:TEX101(gene name)|psi-mi:TEX101(display_short)|uniprotkb:Cell surface receptor NYD-SP8(gene name synonym)|uniprotkb:SGRG(gene name synonym)|uniprotkb:Scleroderma-associated autoantigen(gene name synonym)|uniprotkb:Spermatogenesis-related gene protein(gene name synonym)|uniprotkb:UNQ867/PRO1884(orf name) psi-mi:kap3_human(display_long)|uniprotkb:PRKAR2B(gene name)|psi-mi:PRKAR2B(display_short) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Schiza et al. (2018) imex:IM-28077|pubmed:30097533 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-25504841|imex:IM-28077-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000131126(gene)|ensembl:ENST00000598265(transcript)|go:"GO:0001669"(acrosomal vesicle)|go:"GO:0002080"(acrosomal membrane)|go:"GO:0005576"(extracellular region)|go:"GO:0005886"(plasma membrane)|go:"GO:0007339"(binding of sperm to zona pellucida)|go:"GO:0009566"(fertilization)|go:"GO:0030317"(flagellated sperm motility)|go:"GO:0044853"(plasma membrane raft)|go:"GO:0046658"(anchored component of plasma membrane)|go:"GO:1901317"(regulation of flagellated sperm motility)|interpro:IPR016054(Ly-6 antigen / uPA receptor -like)|rcsb pdb:7BPR|reactome:R-HSA-163125|refseq:NP_001123483.1|refseq:NP_113639.4 ensembl:ENSG00000005249(gene)|ensembl:ENSG00000284096(gene)|ensembl:ENST00000265717(transcript)|ensembl:ENST00000639737(transcript)|go:"GO:0004862"(cAMP-dependent protein kinase inhibitor activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006631"(fatty acid metabolic process)|go:"GO:0005952"(cAMP-dependent protein kinase complex)|go:"GO:0007612"(learning)|go:"GO:0008603"(cAMP-dependent protein kinase regulator activity)|go:"GO:0010738"(regulation of protein kinase A signaling)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030552"(cAMP binding)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0034236"(protein kinase A catalytic subunit binding)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043197"(dendritic spine)|go:"GO:0043198"(dendritic shaft)|go:"GO:0043949"(regulation of cAMP-mediated signaling)|go:"GO:0045121"(membrane raft)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0050804"(modulation of chemical synaptic transmission)|go:"GO:0070062"(extracellular exosome)|go:"GO:0097332"(response to antipsychotic drug)|go:"GO:0097338"(response to clozapine)|go:"GO:0097546"(ciliary base)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:2000480"(negative regulation of cAMP-dependent protein kinase activity)|interpro:IPR000595(Cyclic nucleotide-binding)|interpro:IPR003117(cAMP-dependent protein kinase, regulatory subunit, type I/II alpha/beta)|interpro:IPR012198(cAMP-dependent protein kinase regulatory subunit)|interpro:IPR014710(RmlC-like jelly roll fold)|interpro:IPR018488|interpro:IPR018490|mint:P31323|reactome:R-HSA-163615|reactome:R-HSA-164378|reactome:R-HSA-180024|reactome:R-HSA-2565942|reactome:R-HSA-380259|reactome:R-HSA-380270|reactome:R-HSA-380284|reactome:R-HSA-380320|reactome:R-HSA-381676|reactome:R-HSA-432040|reactome:R-HSA-442720|reactome:R-HSA-5610787|reactome:R-HSA-5620912|reactome:R-HSA-8854518|reactome:R-HSA-9660821|reactome:R-HSA-9664323|reactome:R-HSA-983231|refseq:NP_002727.2|dip:DIP-554N - - - figure legend:Supp Table S4 and Supp Fig. S3|comment:"Coimmunoprecipitation with 34ED229 (T2) anti-TEX101 antibody"|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-testis)|taxid:9606(Homo sapiens) - 2020/03/24 2020/06/18 rogid:ZE4tXTFi7lUCcIbCL4KHzY3a6xM9606 rogid:P643dCCYtpt/EkR7tmZrbo97FLE9606 rigid:2wTqH12DHkSLcixvnxiJPZhqAc0 false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9BY14 uniprotkb:P50914 intact:EBI-12549378|ensembl:ENSP00000472769|uniprotkb:Q7L5R2|uniprotkb:Q9BPY7 intact:EBI-356746|uniprotkb:Q45RF0|uniprotkb:Q53G20|uniprotkb:Q8TBD5|uniprotkb:Q8WUT0|uniprotkb:Q92579|uniprotkb:Q96GR0|uniprotkb:Q9BSB8|uniprotkb:Q9BW65|uniprotkb:Q9BYF6|ensembl:ENSP00000345156|ensembl:ENSP00000379506 psi-mi:tx101_human(display_long)|uniprotkb:TEX101(gene name)|psi-mi:TEX101(display_short)|uniprotkb:Cell surface receptor NYD-SP8(gene name synonym)|uniprotkb:SGRG(gene name synonym)|uniprotkb:Scleroderma-associated autoantigen(gene name synonym)|uniprotkb:Spermatogenesis-related gene protein(gene name synonym)|uniprotkb:UNQ867/PRO1884(orf name) psi-mi:rl14_human(display_long)|uniprotkb:RPL14(gene name)|psi-mi:RPL14(display_short)|uniprotkb:CAG-ISL 7(gene name synonym)|uniprotkb:Large ribosomal subunit protein eL14(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Schiza et al. (2018) imex:IM-28077|pubmed:30097533 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-25504841|imex:IM-28077-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000131126(gene)|ensembl:ENST00000598265(transcript)|go:"GO:0001669"(acrosomal vesicle)|go:"GO:0002080"(acrosomal membrane)|go:"GO:0005576"(extracellular region)|go:"GO:0005886"(plasma membrane)|go:"GO:0007339"(binding of sperm to zona pellucida)|go:"GO:0009566"(fertilization)|go:"GO:0030317"(flagellated sperm motility)|go:"GO:0044853"(plasma membrane raft)|go:"GO:0046658"(anchored component of plasma membrane)|go:"GO:1901317"(regulation of flagellated sperm motility)|interpro:IPR016054(Ly-6 antigen / uPA receptor -like)|rcsb pdb:7BPR|reactome:R-HSA-163125|refseq:NP_001123483.1|refseq:NP_113639.4 refseq:NP_001030168.1|refseq:NP_003964.3|go:"GO:0045296"(cadherin binding)|go:"GO:0070062"(extracellular exosome)|interpro:IPR002784(Ribosomal protein L14)|interpro:IPR008991(Translation protein SH3-like)|ensembl:ENSG00000188846(gene)|ensembl:ENST00000338970(transcript)|ensembl:ENST00000396203(transcript)|go:"GO:0002181"(cytoplasmic translation)|go:"GO:0003723"(RNA binding)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005829"(cytosol)|go:"GO:0006364"(rRNA processing)|go:"GO:0006412"(translation)|go:"GO:0014069"(postsynaptic density)|go:"GO:0016020"(membrane)|go:"GO:0022625"(cytosolic large ribosomal subunit)|go:"GO:0022626"(cytosolic ribosome)|go:"GO:0042273"(ribosomal large subunit biogenesis)|interpro:IPR014722(Translation protein SH3-like, subgroup)|interpro:IPR041985|mint:P50914|rcsb pdb:4UG0|rcsb pdb:4V6X|rcsb pdb:5AJ0|rcsb pdb:5LKS|rcsb pdb:5T2C|rcsb pdb:6EK0|rcsb pdb:6IP5|rcsb pdb:6IP6|rcsb pdb:6IP8|rcsb pdb:6LQM|rcsb pdb:6LSR|rcsb pdb:6LSS|rcsb pdb:6LU8|rcsb pdb:6OLE|rcsb pdb:6OLF|rcsb pdb:6OLG|rcsb pdb:6OLI|rcsb pdb:6OLZ|interpro:IPR039660|rcsb pdb:6OM0|rcsb pdb:6OM7|rcsb pdb:6QZP|rcsb pdb:6W6L|rcsb pdb:6XA1|rcsb pdb:6Y0G|rcsb pdb:6Y57|rcsb pdb:6Y6X|rcsb pdb:6Z6L|rcsb pdb:6Z6M|rcsb pdb:6Z6N|rcsb pdb:6ZM7|rcsb pdb:6ZME|rcsb pdb:6ZMI|rcsb pdb:6ZMO|rcsb pdb:7BHP|reactome:R-HSA-156827|reactome:R-HSA-156902|reactome:R-HSA-1799339|reactome:R-HSA-192823|reactome:R-HSA-2408557|reactome:R-HSA-6791226|reactome:R-HSA-72689|reactome:R-HSA-72706|reactome:R-HSA-72764|reactome:R-HSA-9010553|reactome:R-HSA-9633012|reactome:R-HSA-975956|reactome:R-HSA-975957|rcsb pdb:6Y2L - - - figure legend:Supp Table S4 and Supp Fig. S3|comment:"Coimmunoprecipitation with 34ED229 (T2) anti-TEX101 antibody"|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-testis)|taxid:9606(Homo sapiens) - 2020/03/24 2020/06/18 rogid:ZE4tXTFi7lUCcIbCL4KHzY3a6xM9606 rogid:AjaguD5hgHtcBbJq5QfuG6XdTcE9606 rigid:2wTqH12DHkSLcixvnxiJPZhqAc0 false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9BY14 uniprotkb:Q9P2R7 intact:EBI-12549378|ensembl:ENSP00000472769|uniprotkb:Q7L5R2|uniprotkb:Q9BPY7 intact:EBI-2269898|uniprotkb:O95194|uniprotkb:Q5T9Q4|uniprotkb:Q5T9Q6|uniprotkb:Q9NV21|uniprotkb:Q9NVP7|uniprotkb:B2RDE7|ensembl:ENSP00000494360|ensembl:ENSP00000494987 psi-mi:tx101_human(display_long)|uniprotkb:TEX101(gene name)|psi-mi:TEX101(display_short)|uniprotkb:Cell surface receptor NYD-SP8(gene name synonym)|uniprotkb:SGRG(gene name synonym)|uniprotkb:Scleroderma-associated autoantigen(gene name synonym)|uniprotkb:Spermatogenesis-related gene protein(gene name synonym)|uniprotkb:UNQ867/PRO1884(orf name) psi-mi:sucb1_human(display_long)|uniprotkb:SUCLA2(gene name)|psi-mi:SUCLA2(display_short)|uniprotkb:ATP-specific succinyl-CoA synthetase subunit beta(gene name synonym)|uniprotkb:Succinyl-CoA synthetase beta-A chain(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Schiza et al. (2018) imex:IM-28077|pubmed:30097533 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-25504841|imex:IM-28077-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000131126(gene)|ensembl:ENST00000598265(transcript)|go:"GO:0001669"(acrosomal vesicle)|go:"GO:0002080"(acrosomal membrane)|go:"GO:0005576"(extracellular region)|go:"GO:0005886"(plasma membrane)|go:"GO:0007339"(binding of sperm to zona pellucida)|go:"GO:0009566"(fertilization)|go:"GO:0030317"(flagellated sperm motility)|go:"GO:0044853"(plasma membrane raft)|go:"GO:0046658"(anchored component of plasma membrane)|go:"GO:1901317"(regulation of flagellated sperm motility)|interpro:IPR016054(Ly-6 antigen / uPA receptor -like)|rcsb pdb:7BPR|reactome:R-HSA-163125|refseq:NP_001123483.1|refseq:NP_113639.4 refseq:NP_003841.1|ensembl:ENSG00000136143(gene)|ensembl:ENST00000643584(transcript)|ensembl:ENST00000646932(transcript)|go:"GO:0000287"(magnesium ion binding)|go:"GO:0004775"("succinate-CoA ligase (ADP-forming) activity")|go:"GO:0004776"("succinate-CoA ligase (GDP-forming) activity")|go:"GO:0005524"(ATP binding)|go:"GO:0005739"(mitochondrion)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0006099"(tricarboxylic acid cycle)|go:"GO:0006104"(succinyl-CoA metabolic process)|go:"GO:0006105"(succinate metabolic process)|go:"GO:0006781"(succinyl-CoA pathway)|go:"GO:0042709"(succinate-CoA ligase complex)|go:"GO:0070062"(extracellular exosome)|interpro:IPR005809(Succinyl-CoA synthetase, beta subunit)|interpro:IPR005811(ATP-citrate lyase/succinyl-CoA ligase)|interpro:IPR011761(ATP-grasp fold)|interpro:IPR013650(ATP-grasp fold, succinyl-CoA synthetase-type)|interpro:IPR013815(ATP-grasp fold, subdomain 1)|interpro:IPR016102(Succinyl-CoA synthetase-like)|interpro:IPR017866|interpro:IPR034723|mint:Q9P2R7|rcsb pdb:6G4Q|reactome:R-HSA-71403 - - - figure legend:Supp Table S4 and Supp Fig. S3|comment:"Coimmunoprecipitation with 34ED229 (T2) anti-TEX101 antibody"|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-testis)|taxid:9606(Homo sapiens) - 2020/03/24 2020/06/18 rogid:ZE4tXTFi7lUCcIbCL4KHzY3a6xM9606 rogid:I/FQp3c8ckxpxoyftKge2B5lDmI9606 rigid:2wTqH12DHkSLcixvnxiJPZhqAc0 false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9BY14 uniprotkb:Q16853 intact:EBI-12549378|ensembl:ENSP00000472769|uniprotkb:Q7L5R2|uniprotkb:Q9BPY7 intact:EBI-3921628|uniprotkb:B2RCI5|uniprotkb:Q45F94|ensembl:ENSP00000312326|uniprotkb:L0L8N9|uniprotkb:K7ESB3 psi-mi:tx101_human(display_long)|uniprotkb:TEX101(gene name)|psi-mi:TEX101(display_short)|uniprotkb:Cell surface receptor NYD-SP8(gene name synonym)|uniprotkb:SGRG(gene name synonym)|uniprotkb:Scleroderma-associated autoantigen(gene name synonym)|uniprotkb:Spermatogenesis-related gene protein(gene name synonym)|uniprotkb:UNQ867/PRO1884(orf name) psi-mi:aoc3_human(display_long)|uniprotkb:AOC3(gene name)|psi-mi:AOC3(display_short)|uniprotkb:VAP1(gene name synonym)|uniprotkb:Copper amine oxidase(gene name synonym)|uniprotkb:HPAO(gene name synonym)|uniprotkb:Semicarbazide-sensitive amine oxidase(gene name synonym)|uniprotkb:Vascular adhesion protein 1(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Schiza et al. (2018) imex:IM-28077|pubmed:30097533 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-25504841|imex:IM-28077-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000131126(gene)|ensembl:ENST00000598265(transcript)|go:"GO:0001669"(acrosomal vesicle)|go:"GO:0002080"(acrosomal membrane)|go:"GO:0005576"(extracellular region)|go:"GO:0005886"(plasma membrane)|go:"GO:0007339"(binding of sperm to zona pellucida)|go:"GO:0009566"(fertilization)|go:"GO:0030317"(flagellated sperm motility)|go:"GO:0044853"(plasma membrane raft)|go:"GO:0046658"(anchored component of plasma membrane)|go:"GO:1901317"(regulation of flagellated sperm motility)|interpro:IPR016054(Ly-6 antigen / uPA receptor -like)|rcsb pdb:7BPR|reactome:R-HSA-163125|refseq:NP_001123483.1|refseq:NP_113639.4 refseq:NP_001264660.1|refseq:NP_001264661.1|refseq:NP_003725.1|ensembl:ENSG00000131471(gene)|ensembl:ENST00000308423(transcript)|go:"GO:0005507"(copper ion binding)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005769"(early endosome)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0005902"(microvillus)|go:"GO:0006954"(inflammatory response)|go:"GO:0007155"(cell adhesion)|go:"GO:0008131"(primary amine oxidase activity)|go:"GO:0009308"(amine metabolic process)|go:"GO:0009986"(cell surface)|go:"GO:0016021"(integral component of membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0046677"(response to antibiotic)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0048038"(quinone binding)|go:"GO:0052593"("tryptamine:oxygen oxidoreductase (deaminating) activity")|go:"GO:0052594"("aminoacetone:oxygen oxidoreductase(deaminating) activity")|go:"GO:0052595"(aliphatic-amine oxidase activity)|go:"GO:0052596"("phenethylamine:oxygen oxidoreductase (deaminating) activity")|go:"GO:1902283"(negative regulation of primary amine oxidase activity)|interpro:IPR000269(Copper amine oxidase)|interpro:IPR015798(Copper amine oxidase, C-terminal)|interpro:IPR015800(Copper amine oxidase, N2-terminal)|interpro:IPR015802(Copper amine oxidase, N3-terminal)|interpro:IPR016182(Copper amine oxidase, N-terminal region)|interpro:IPR036460|rcsb pdb:1PU4|rcsb pdb:1US1|rcsb pdb:2C10|rcsb pdb:2C11|rcsb pdb:2Y73|rcsb pdb:2Y74|rcsb pdb:3ALA|rcsb pdb:4BTW|rcsb pdb:4BTX|rcsb pdb:4BTY|reactome:R-HSA-211945 - - - figure legend:Supp Table S4 and Supp Fig. S3|comment:"Coimmunoprecipitation with 34ED229 (T2) anti-TEX101 antibody"|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-testis)|taxid:9606(Homo sapiens) - 2020/03/24 2020/06/18 rogid:ZE4tXTFi7lUCcIbCL4KHzY3a6xM9606 rogid:t7ZSUp32sGH23Gfa+V0Lult17Fw9606 rigid:2wTqH12DHkSLcixvnxiJPZhqAc0 false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9BY14 uniprotkb:Q71UM5 intact:EBI-12549378|ensembl:ENSP00000472769|uniprotkb:Q7L5R2|uniprotkb:Q9BPY7 intact:EBI-355126|uniprotkb:Q9BTJ1|ensembl:ENSP00000331019 psi-mi:tx101_human(display_long)|uniprotkb:TEX101(gene name)|psi-mi:TEX101(display_short)|uniprotkb:Cell surface receptor NYD-SP8(gene name synonym)|uniprotkb:SGRG(gene name synonym)|uniprotkb:Scleroderma-associated autoantigen(gene name synonym)|uniprotkb:Spermatogenesis-related gene protein(gene name synonym)|uniprotkb:UNQ867/PRO1884(orf name) psi-mi:rs27l_human(display_long)|uniprotkb:RPS27L(gene name)|psi-mi:RPS27L(display_short)|uniprotkb:Small ribosomal subunit protein eS27-like(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Schiza et al. (2018) imex:IM-28077|pubmed:30097533 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-25504841|imex:IM-28077-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000131126(gene)|ensembl:ENST00000598265(transcript)|go:"GO:0001669"(acrosomal vesicle)|go:"GO:0002080"(acrosomal membrane)|go:"GO:0005576"(extracellular region)|go:"GO:0005886"(plasma membrane)|go:"GO:0007339"(binding of sperm to zona pellucida)|go:"GO:0009566"(fertilization)|go:"GO:0030317"(flagellated sperm motility)|go:"GO:0044853"(plasma membrane raft)|go:"GO:0046658"(anchored component of plasma membrane)|go:"GO:1901317"(regulation of flagellated sperm motility)|interpro:IPR016054(Ly-6 antigen / uPA receptor -like)|rcsb pdb:7BPR|reactome:R-HSA-163125|refseq:NP_001123483.1|refseq:NP_113639.4 refseq:NP_057004.1|ensembl:ENSG00000185088(gene)|ensembl:ENST00000330964(transcript)|go:"GO:0000028"(ribosomal small subunit assembly)|go:"GO:0003723"(RNA binding)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005634"(nucleus)|go:"GO:0006412"(translation)|go:"GO:0006919"(activation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0006978"(DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator)|go:"GO:0008494"(translation activator activity)|go:"GO:0008656"(cysteine-type endopeptidase activator activity involved in apoptotic process)|go:"GO:0022627"(cytosolic small ribosomal subunit)|go:"GO:0031571"(mitotic G1 DNA damage checkpoint signaling)|go:"GO:0042771"(intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator)|go:"GO:0045727"(positive regulation of translation)|go:"GO:0046872"(metal ion binding)|interpro:IPR000592(Ribosomal protein S27e)|interpro:IPR011332(Ribosomal protein, zinc-binding)|interpro:IPR023407|mint:Q71UM5|reactome:R-HSA-156827|reactome:R-HSA-156902|reactome:R-HSA-1799339|reactome:R-HSA-192823|reactome:R-HSA-2408557|reactome:R-HSA-6791226|reactome:R-HSA-72649|reactome:R-HSA-72689|reactome:R-HSA-72695|reactome:R-HSA-72702|reactome:R-HSA-72706|reactome:R-HSA-72764|reactome:R-HSA-9010553|reactome:R-HSA-9633012|reactome:R-HSA-975956|reactome:R-HSA-975957 - - - figure legend:Supp Table S4 and Supp Fig. S3|comment:"Coimmunoprecipitation with 34ED229 (T2) anti-TEX101 antibody"|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-testis)|taxid:9606(Homo sapiens) - 2020/03/24 2020/06/18 rogid:ZE4tXTFi7lUCcIbCL4KHzY3a6xM9606 rogid:OVIAlDF6dN3DxLZgQFrFl8r0Z0I9606 rigid:2wTqH12DHkSLcixvnxiJPZhqAc0 false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9BY14 uniprotkb:Q9UNX3 intact:EBI-12549378|ensembl:ENSP00000472769|uniprotkb:Q7L5R2|uniprotkb:Q9BPY7 intact:EBI-2949703|ensembl:ENSP00000265100|ensembl:ENSP00000428177|ensembl:ENSP00000428223|ensembl:ENSP00000430147|uniprotkb:B3KY82|uniprotkb:D3DQM0 psi-mi:tx101_human(display_long)|uniprotkb:TEX101(gene name)|psi-mi:TEX101(display_short)|uniprotkb:Cell surface receptor NYD-SP8(gene name synonym)|uniprotkb:SGRG(gene name synonym)|uniprotkb:Scleroderma-associated autoantigen(gene name synonym)|uniprotkb:Spermatogenesis-related gene protein(gene name synonym)|uniprotkb:UNQ867/PRO1884(orf name) psi-mi:rl26l_human(display_long)|uniprotkb:RPL26L1(gene name)|psi-mi:RPL26L1(display_short)|uniprotkb:RPL26P1(gene name synonym)|uniprotkb:Large ribosomal subunit protein uL24-like 1(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Schiza et al. (2018) imex:IM-28077|pubmed:30097533 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-25504841|imex:IM-28077-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000131126(gene)|ensembl:ENST00000598265(transcript)|go:"GO:0001669"(acrosomal vesicle)|go:"GO:0002080"(acrosomal membrane)|go:"GO:0005576"(extracellular region)|go:"GO:0005886"(plasma membrane)|go:"GO:0007339"(binding of sperm to zona pellucida)|go:"GO:0009566"(fertilization)|go:"GO:0030317"(flagellated sperm motility)|go:"GO:0044853"(plasma membrane raft)|go:"GO:0046658"(anchored component of plasma membrane)|go:"GO:1901317"(regulation of flagellated sperm motility)|interpro:IPR016054(Ly-6 antigen / uPA receptor -like)|rcsb pdb:7BPR|reactome:R-HSA-163125|refseq:NP_001123483.1|refseq:NP_113639.4 ensembl:ENSG00000037241(gene)|ensembl:ENST00000265100(transcript)|ensembl:ENST00000519239(transcript)|ensembl:ENST00000519974(transcript)|ensembl:ENST00000521476(transcript)|go:"GO:0002181"(cytoplasmic translation)|go:"GO:0003723"(RNA binding)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0022625"(cytosolic large ribosomal subunit)|go:"GO:0042273"(ribosomal large subunit biogenesis)|go:"GO:0070062"(extracellular exosome)|interpro:IPR005756(Ribosomal protein L26, eukaryotic/archaeal)|interpro:IPR005824(KOW)|interpro:IPR005825(Ribosomal protein L24/L26, conserved site)|interpro:IPR008991(Translation protein SH3-like)|interpro:IPR014722(Translation protein SH3-like, subgroup)|interpro:IPR041988|mint:Q9UNX3|reactome:R-HSA-156827|reactome:R-HSA-156902|reactome:R-HSA-1799339|reactome:R-HSA-192823|reactome:R-HSA-6791226|reactome:R-HSA-72689|reactome:R-HSA-72706|reactome:R-HSA-72764|reactome:R-HSA-9010553|reactome:R-HSA-9633012|reactome:R-HSA-975956|reactome:R-HSA-975957|reactome:R-HSA-2408557|refseq:NP_057177.1|refseq:XP_011532867.1|refseq:NP_001304909.1|refseq:NP_001304910.1|refseq:NP_001304911.1|refseq:XP_016865008.1|refseq:XP_016865009.1 - - - figure legend:Supp Table S4 and Supp Fig. S3|comment:"Coimmunoprecipitation with 34ED229 (T2) anti-TEX101 antibody"|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-testis)|taxid:9606(Homo sapiens) - 2020/03/24 2020/06/18 rogid:ZE4tXTFi7lUCcIbCL4KHzY3a6xM9606 rogid:dny/DWK4MvWD3FUJvW5+KGI3iJI9606 rigid:2wTqH12DHkSLcixvnxiJPZhqAc0 false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9BY14 uniprotkb:O75915 intact:EBI-12549378|ensembl:ENSP00000472769|uniprotkb:Q7L5R2|uniprotkb:Q9BPY7 intact:EBI-2860752|uniprotkb:B2R6V5|uniprotkb:Q53ES3|uniprotkb:Q5KU08|ensembl:ENSP00000273258 psi-mi:tx101_human(display_long)|uniprotkb:TEX101(gene name)|psi-mi:TEX101(display_short)|uniprotkb:Cell surface receptor NYD-SP8(gene name synonym)|uniprotkb:SGRG(gene name synonym)|uniprotkb:Scleroderma-associated autoantigen(gene name synonym)|uniprotkb:Spermatogenesis-related gene protein(gene name synonym)|uniprotkb:UNQ867/PRO1884(orf name) psi-mi:praf3_human(display_long)|uniprotkb:ARL6IP5(gene name)|psi-mi:ARL6IP5(display_short)|uniprotkb:DERP11(gene name synonym)|uniprotkb:JWA(gene name synonym)|uniprotkb:PRA2(gene name synonym)|uniprotkb:PRAF3(gene name synonym)|uniprotkb:ADP-ribosylation factor-like protein 6-interacting protein 5(gene name synonym)|uniprotkb:Cytoskeleton-related vitamin A-responsive protein(gene name synonym)|uniprotkb:Dermal papilla-derived protein 11(gene name synonym)|uniprotkb:GTRAP3-18(gene name synonym)|uniprotkb:Glutamate transporter EAAC1-interacting protein(gene name synonym)|uniprotkb:JM5(gene name synonym)|uniprotkb:Prenylated Rab acceptor protein 2(gene name synonym)|uniprotkb:Protein JWa(gene name synonym)|uniprotkb:Putative MAPK-activating protein PM27(gene name synonym)|uniprotkb:HSPC127(orf name) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Schiza et al. (2018) imex:IM-28077|pubmed:30097533 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-25504841|imex:IM-28077-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000131126(gene)|ensembl:ENST00000598265(transcript)|go:"GO:0001669"(acrosomal vesicle)|go:"GO:0002080"(acrosomal membrane)|go:"GO:0005576"(extracellular region)|go:"GO:0005886"(plasma membrane)|go:"GO:0007339"(binding of sperm to zona pellucida)|go:"GO:0009566"(fertilization)|go:"GO:0030317"(flagellated sperm motility)|go:"GO:0044853"(plasma membrane raft)|go:"GO:0046658"(anchored component of plasma membrane)|go:"GO:1901317"(regulation of flagellated sperm motility)|interpro:IPR016054(Ly-6 antigen / uPA receptor -like)|rcsb pdb:7BPR|reactome:R-HSA-163125|refseq:NP_001123483.1|refseq:NP_113639.4 refseq:NP_006398.1|go:"GO:0043280"(positive regulation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0051051"(negative regulation of transport)|go:"GO:0071407"(cellular response to organic cyclic compound)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0098712"(L-glutamate import across plasma membrane)|interpro:IPR004895(Prenylated rab acceptor PRA1)|mint:O75915|reactome:R-HSA-210500|ensembl:ENSG00000144746(gene)|ensembl:ENST00000273258(transcript)|go:"GO:0002037"(negative regulation of L-glutamate import across plasma membrane)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005886"(plasma membrane)|go:"GO:0006749"(glutathione metabolic process)|go:"GO:0007611"(learning or memory)|go:"GO:0008631"(intrinsic apoptotic signaling pathway in response to oxidative stress)|go:"GO:0010917"(negative regulation of mitochondrial membrane potential)|go:"GO:0015031"(protein transport)|go:"GO:0015813"(L-glutamate transmembrane transport)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0032874"(positive regulation of stress-activated MAPK cascade)|go:"GO:0036475"(neuron death in response to oxidative stress)|go:"GO:0043065"(positive regulation of apoptotic process) - - - figure legend:Supp Table S4 and Supp Fig. S3|comment:"Coimmunoprecipitation with 34ED229 (T2) anti-TEX101 antibody"|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-testis)|taxid:9606(Homo sapiens) - 2020/03/24 2020/06/18 rogid:ZE4tXTFi7lUCcIbCL4KHzY3a6xM9606 rogid:TG2yH1gqzVhFgxBtuZqsE1dLAvQ9606 rigid:2wTqH12DHkSLcixvnxiJPZhqAc0 false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9BY14 uniprotkb:P13073 intact:EBI-12549378|ensembl:ENSP00000472769|uniprotkb:Q7L5R2|uniprotkb:Q9BPY7 intact:EBI-1056574|uniprotkb:B2R4J2|uniprotkb:D3DUM7|uniprotkb:Q6P666|ensembl:ENSP00000253452|ensembl:ENSP00000457015|ensembl:ENSP00000457513 psi-mi:tx101_human(display_long)|uniprotkb:TEX101(gene name)|psi-mi:TEX101(display_short)|uniprotkb:Cell surface receptor NYD-SP8(gene name synonym)|uniprotkb:SGRG(gene name synonym)|uniprotkb:Scleroderma-associated autoantigen(gene name synonym)|uniprotkb:Spermatogenesis-related gene protein(gene name synonym)|uniprotkb:UNQ867/PRO1884(orf name) psi-mi:cox41_human(display_long)|uniprotkb:COX4I1(gene name)|psi-mi:COX4I1(display_short)|uniprotkb:COX4(gene name synonym)|uniprotkb:Cytochrome c oxidase subunit IV isoform 1(gene name synonym)|uniprotkb:Cytochrome c oxidase polypeptide IV(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Schiza et al. (2018) imex:IM-28077|pubmed:30097533 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-25504841|imex:IM-28077-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000131126(gene)|ensembl:ENST00000598265(transcript)|go:"GO:0001669"(acrosomal vesicle)|go:"GO:0002080"(acrosomal membrane)|go:"GO:0005576"(extracellular region)|go:"GO:0005886"(plasma membrane)|go:"GO:0007339"(binding of sperm to zona pellucida)|go:"GO:0009566"(fertilization)|go:"GO:0030317"(flagellated sperm motility)|go:"GO:0044853"(plasma membrane raft)|go:"GO:0046658"(anchored component of plasma membrane)|go:"GO:1901317"(regulation of flagellated sperm motility)|interpro:IPR016054(Ly-6 antigen / uPA receptor -like)|rcsb pdb:7BPR|reactome:R-HSA-163125|refseq:NP_001123483.1|refseq:NP_113639.4 refseq:NP_001852.1|refseq:NP_001305726.1|refseq:NP_001305731.1|refseq:NP_001305715.1|refseq:NP_001305717.1|refseq:NP_001305723.1|ensembl:ENSG00000131143(gene)|ensembl:ENST00000253452(transcript)|ensembl:ENST00000561569(transcript)|ensembl:ENST00000562336(transcript)|go:"GO:0004129"(cytochrome-c oxidase activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005751"(mitochondrial respiratory chain complex IV)|go:"GO:0005829"(cytosol)|go:"GO:0006091"(generation of precursor metabolites and energy)|go:"GO:0006123"(mitochondrial electron transport, cytochrome c to oxygen)|go:"GO:0007584"(response to nutrient)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|interpro:IPR004203(Cytochrome c oxidase subunit IV)|interpro:IPR013288(Cytochrome c oxidase subunit 4)|interpro:IPR036639|mint:P13073|rcsb pdb:5Z62|reactome:R-HSA-5628897|reactome:R-HSA-611105|reactome:R-HSA-9707564 - - - figure legend:Supp Table S4 and Supp Fig. S3|comment:"Coimmunoprecipitation with 34ED229 (T2) anti-TEX101 antibody"|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-testis)|taxid:9606(Homo sapiens) - 2020/03/24 2020/06/18 rogid:ZE4tXTFi7lUCcIbCL4KHzY3a6xM9606 rogid:7TbisLJIPPlFeZNNXqP9SciPjLw9606 rigid:2wTqH12DHkSLcixvnxiJPZhqAc0 false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9BY14 uniprotkb:Q99460 intact:EBI-12549378|ensembl:ENSP00000472769|uniprotkb:Q7L5R2|uniprotkb:Q9BPY7 intact:EBI-357874|uniprotkb:Q24JU0|uniprotkb:Q53TI2|uniprotkb:Q6GMU5|uniprotkb:Q6P2P4|uniprotkb:Q6PJM7|uniprotkb:Q6PKG9|uniprotkb:B8ZZH9|uniprotkb:Q86VU1|uniprotkb:Q8IV79|ensembl:ENSP00000309474|ensembl:ENSP00000503068 psi-mi:tx101_human(display_long)|uniprotkb:TEX101(gene name)|psi-mi:TEX101(display_short)|uniprotkb:Cell surface receptor NYD-SP8(gene name synonym)|uniprotkb:SGRG(gene name synonym)|uniprotkb:Scleroderma-associated autoantigen(gene name synonym)|uniprotkb:Spermatogenesis-related gene protein(gene name synonym)|uniprotkb:UNQ867/PRO1884(orf name) psi-mi:psmd1_human(display_long)|uniprotkb:PSMD1(gene name)|psi-mi:PSMD1(display_short)|uniprotkb:26S proteasome regulatory subunit RPN2(gene name synonym)|uniprotkb:26S proteasome regulatory subunit S1(gene name synonym)|uniprotkb:26S proteasome subunit p112(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Schiza et al. (2018) imex:IM-28077|pubmed:30097533 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-25504841|imex:IM-28077-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000131126(gene)|ensembl:ENST00000598265(transcript)|go:"GO:0001669"(acrosomal vesicle)|go:"GO:0002080"(acrosomal membrane)|go:"GO:0005576"(extracellular region)|go:"GO:0005886"(plasma membrane)|go:"GO:0007339"(binding of sperm to zona pellucida)|go:"GO:0009566"(fertilization)|go:"GO:0030317"(flagellated sperm motility)|go:"GO:0044853"(plasma membrane raft)|go:"GO:0046658"(anchored component of plasma membrane)|go:"GO:1901317"(regulation of flagellated sperm motility)|interpro:IPR016054(Ly-6 antigen / uPA receptor -like)|rcsb pdb:7BPR|reactome:R-HSA-163125|refseq:NP_001123483.1|refseq:NP_113639.4 refseq:NP_001177966.1|refseq:NP_002798.2|dip:DIP-27548N|ensembl:ENSG00000173692(gene)|ensembl:ENST00000308696(transcript)|ensembl:ENST00000677230(transcript)|go:"GO:0000502"(proteasome complex)|go:"GO:0005576"(extracellular region)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005838"(proteasome regulatory particle)|go:"GO:0008540"(proteasome regulatory particle, base subcomplex)|go:"GO:0016020"(membrane)|go:"GO:0022624"(proteasome accessory complex)|go:"GO:0030234"(enzyme regulator activity)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0034515"(proteasome storage granule)|go:"GO:0035578"(azurophil granule lumen)|go:"GO:0042176"(regulation of protein catabolic process)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|interpro:IPR002015(Proteasome/cyclosome, regulatory subunit)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR016642(26S proteasome regulatory complex, non-ATPase subcomplex, Rpn2/Psmd1 subunit)|interpro:IPR035266|interpro:IPR040623|mint:Q99460|rcsb pdb:5GJQ|rcsb pdb:5GJR|rcsb pdb:5L4K|rcsb pdb:5LN3|rcsb pdb:5M32|rcsb pdb:5T0C|rcsb pdb:5T0G|rcsb pdb:5T0H|rcsb pdb:5T0I|rcsb pdb:5T0J|rcsb pdb:5V1Y|rcsb pdb:5V1Z|rcsb pdb:5VFP|rcsb pdb:5VFQ|rcsb pdb:5VFR|rcsb pdb:5VFS|rcsb pdb:5VFT|rcsb pdb:5VFU|rcsb pdb:5VGZ|rcsb pdb:5VHF|rcsb pdb:5VHH|rcsb pdb:5VHI|rcsb pdb:5VHS|rcsb pdb:6CO4|rcsb pdb:6MSB|rcsb pdb:6MSD|rcsb pdb:6MSE|rcsb pdb:6MSG|rcsb pdb:6MSH|rcsb pdb:6MSJ|rcsb pdb:6MSK|rcsb pdb:6OI4|rcsb pdb:6UYI|rcsb pdb:6UYJ|rcsb pdb:6WJD|rcsb pdb:6WJN|reactome:R-HSA-1169091|reactome:R-HSA-1234176|reactome:R-HSA-1236974|reactome:R-HSA-1236978|reactome:R-HSA-174084|reactome:R-HSA-174113|reactome:R-HSA-174154|reactome:R-HSA-174178|reactome:R-HSA-174184|reactome:R-HSA-180534|reactome:R-HSA-180585|reactome:R-HSA-187577|reactome:R-HSA-195253|reactome:R-HSA-202424|reactome:R-HSA-211733|reactome:R-HSA-2467813|reactome:R-HSA-2871837|reactome:R-HSA-349425|reactome:R-HSA-350562|reactome:R-HSA-450408|reactome:R-HSA-4608870|reactome:R-HSA-4641257|reactome:R-HSA-382556|reactome:R-HSA-4641258|reactome:R-HSA-5358346|reactome:R-HSA-5362768|reactome:R-HSA-5607761|reactome:R-HSA-5607764|reactome:R-HSA-5610780|reactome:R-HSA-5610783|reactome:R-HSA-5610785|reactome:R-HSA-5632684|reactome:R-HSA-5658442|reactome:R-HSA-5668541|reactome:R-HSA-5676590|reactome:R-HSA-5678895|reactome:R-HSA-5687128|reactome:R-HSA-5689603|reactome:R-HSA-5689880|reactome:R-HSA-6798695|reactome:R-HSA-68827|reactome:R-HSA-68949|reactome:R-HSA-69017|reactome:R-HSA-69481|reactome:R-HSA-69601|reactome:R-HSA-75815|reactome:R-HSA-8852276|reactome:R-HSA-8854050|reactome:R-HSA-8932339|reactome:R-HSA-8939236|reactome:R-HSA-8939902|reactome:R-HSA-8941858|reactome:R-HSA-8948751|reactome:R-HSA-8951664|reactome:R-HSA-9010553|reactome:R-HSA-9020702|reactome:R-HSA-9604323|reactome:R-HSA-983168 - - - figure legend:Supp Table S4 and Supp Fig. S3|comment:"Coimmunoprecipitation with 34ED229 (T2) anti-TEX101 antibody"|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-testis)|taxid:9606(Homo sapiens) - 2020/03/24 2020/06/18 rogid:ZE4tXTFi7lUCcIbCL4KHzY3a6xM9606 rogid:aGYxoT30PhzvF/CiurQLDb8Ewrs9606 rigid:2wTqH12DHkSLcixvnxiJPZhqAc0 false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9BY14 uniprotkb:Q1KMD3 intact:EBI-12549378|ensembl:ENSP00000472769|uniprotkb:Q7L5R2|uniprotkb:Q9BPY7 intact:EBI-1059150|uniprotkb:Q8N3B3|ensembl:ENSP00000301785 psi-mi:tx101_human(display_long)|uniprotkb:TEX101(gene name)|psi-mi:TEX101(display_short)|uniprotkb:Cell surface receptor NYD-SP8(gene name synonym)|uniprotkb:SGRG(gene name synonym)|uniprotkb:Scleroderma-associated autoantigen(gene name synonym)|uniprotkb:Spermatogenesis-related gene protein(gene name synonym)|uniprotkb:UNQ867/PRO1884(orf name) psi-mi:hnrl2_human(display_long)|uniprotkb:HNRNPUL2(gene name)|psi-mi:HNRNPUL2(display_short)|uniprotkb:HNRPUL2(gene name synonym)|uniprotkb:Scaffold-attachment factor A2(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Schiza et al. (2018) imex:IM-28077|pubmed:30097533 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-25504841|imex:IM-28077-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000131126(gene)|ensembl:ENST00000598265(transcript)|go:"GO:0001669"(acrosomal vesicle)|go:"GO:0002080"(acrosomal membrane)|go:"GO:0005576"(extracellular region)|go:"GO:0005886"(plasma membrane)|go:"GO:0007339"(binding of sperm to zona pellucida)|go:"GO:0009566"(fertilization)|go:"GO:0030317"(flagellated sperm motility)|go:"GO:0044853"(plasma membrane raft)|go:"GO:0046658"(anchored component of plasma membrane)|go:"GO:1901317"(regulation of flagellated sperm motility)|interpro:IPR016054(Ly-6 antigen / uPA receptor -like)|rcsb pdb:7BPR|reactome:R-HSA-163125|refseq:NP_001123483.1|refseq:NP_113639.4 refseq:NP_001073027.1|ensembl:ENSG00000214753(gene)|ensembl:ENST00000301785(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0016020"(membrane)|interpro:IPR001870("B302 (SPRY)-like")|interpro:IPR003034(DNA-binding SAP)|interpro:IPR003877(SPla/RYanodine receptor SPRY)|interpro:IPR013320(Concanavalin A-like lectin/glucanase, subgroup)|interpro:IPR027417|interpro:IPR035778|interpro:IPR036361|interpro:IPR043136|mint:Q1KMD3 - - - figure legend:Supp Table S4 and Supp Fig. S3|comment:"Coimmunoprecipitation with 34ED229 (T2) anti-TEX101 antibody"|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-testis)|taxid:9606(Homo sapiens) - 2020/03/24 2020/06/18 rogid:ZE4tXTFi7lUCcIbCL4KHzY3a6xM9606 rogid:TOoq1VTfNNzysqSyPH9MHLbSKPA9606 rigid:2wTqH12DHkSLcixvnxiJPZhqAc0 false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9BY14 uniprotkb:Q9UHQ9 intact:EBI-12549378|ensembl:ENSP00000472769|uniprotkb:Q7L5R2|uniprotkb:Q9BPY7 intact:EBI-953870|ensembl:ENSP00000356218|uniprotkb:A0PK21|uniprotkb:O95329|uniprotkb:Q53F73|uniprotkb:Q8NCL5|uniprotkb:Q9UHJ1|uniprotkb:B2R8E0 psi-mi:tx101_human(display_long)|uniprotkb:TEX101(gene name)|psi-mi:TEX101(display_short)|uniprotkb:Cell surface receptor NYD-SP8(gene name synonym)|uniprotkb:SGRG(gene name synonym)|uniprotkb:Scleroderma-associated autoantigen(gene name synonym)|uniprotkb:Spermatogenesis-related gene protein(gene name synonym)|uniprotkb:UNQ867/PRO1884(orf name) psi-mi:nb5r1_human(display_long)|uniprotkb:"NAD(P)H:quinone oxidoreductase type 3 polypeptide A2"(gene name synonym)|uniprotkb:Humb5R2(gene name synonym)|uniprotkb:CYB5R1(gene name)|psi-mi:CYB5R1(display_short)|uniprotkb:NQO3A2(gene name synonym)|uniprotkb:UNQ3049/PRO9865(orf name) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Schiza et al. (2018) imex:IM-28077|pubmed:30097533 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-25504841|imex:IM-28077-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000131126(gene)|ensembl:ENST00000598265(transcript)|go:"GO:0001669"(acrosomal vesicle)|go:"GO:0002080"(acrosomal membrane)|go:"GO:0005576"(extracellular region)|go:"GO:0005886"(plasma membrane)|go:"GO:0007339"(binding of sperm to zona pellucida)|go:"GO:0009566"(fertilization)|go:"GO:0030317"(flagellated sperm motility)|go:"GO:0044853"(plasma membrane raft)|go:"GO:0046658"(anchored component of plasma membrane)|go:"GO:1901317"(regulation of flagellated sperm motility)|interpro:IPR016054(Ly-6 antigen / uPA receptor -like)|rcsb pdb:7BPR|reactome:R-HSA-163125|refseq:NP_001123483.1|refseq:NP_113639.4 ensembl:ENSG00000159348(gene)|ensembl:ENST00000367249(transcript)|go:"GO:0004128"("cytochrome-b5 reductase activity, acting on NAD(P)H")|go:"GO:0005739"(mitochondrion)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005886"(plasma membrane)|go:"GO:0015701"(bicarbonate transport)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016126"(sterol biosynthetic process)|go:"GO:0031092"(platelet alpha granule membrane)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071949"(FAD binding)|interpro:IPR001433("Oxidoreductase FAD/NAD(P)-binding")|interpro:IPR001709(Flavoprotein pyridine nucleotide cytochrome reductase)|interpro:IPR001834("NADH:cytochrome b5 reductase (CBR)")|interpro:IPR008333(Oxidoreductase FAD-binding region)|interpro:IPR017927|interpro:IPR017938|interpro:IPR039261|reactome:R-HSA-114608|reactome:R-HSA-1237044|go:"GO:0016020"(membrane)|refseq:NP_057327.2 - - - figure legend:Supp Table S4 and Supp Fig. S3|comment:"Coimmunoprecipitation with 34ED229 (T2) anti-TEX101 antibody"|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-testis)|taxid:9606(Homo sapiens) - 2020/03/24 2020/06/18 rogid:ZE4tXTFi7lUCcIbCL4KHzY3a6xM9606 rogid:TOvJYSyfYu73Ac/SYjup+ABu74g9606 rigid:2wTqH12DHkSLcixvnxiJPZhqAc0 false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9BY14 uniprotkb:P27144 intact:EBI-12549378|ensembl:ENSP00000472769|uniprotkb:Q7L5R2|uniprotkb:Q9BPY7 intact:EBI-3905025|uniprotkb:B2R927|uniprotkb:Q8IUU9|uniprotkb:Q6NXQ5|uniprotkb:Q6IBH4|uniprotkb:D3DQ62|ensembl:ENSP00000322175|ensembl:ENSP00000378743|ensembl:ENSP00000445912 psi-mi:tx101_human(display_long)|uniprotkb:TEX101(gene name)|psi-mi:TEX101(display_short)|uniprotkb:Cell surface receptor NYD-SP8(gene name synonym)|uniprotkb:SGRG(gene name synonym)|uniprotkb:Scleroderma-associated autoantigen(gene name synonym)|uniprotkb:Spermatogenesis-related gene protein(gene name synonym)|uniprotkb:UNQ867/PRO1884(orf name) psi-mi:kad4_human(display_long)|uniprotkb:AK4(gene name)|psi-mi:AK4(display_short)|uniprotkb:AK3(gene name synonym)|uniprotkb:AK3L1(gene name synonym)|uniprotkb:Adenylate kinase 3-like(gene name synonym)|uniprotkb:"GTP:AMP phosphotransferase AK4"(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Schiza et al. (2018) imex:IM-28077|pubmed:30097533 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-25504841|imex:IM-28077-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000131126(gene)|ensembl:ENST00000598265(transcript)|go:"GO:0001669"(acrosomal vesicle)|go:"GO:0002080"(acrosomal membrane)|go:"GO:0005576"(extracellular region)|go:"GO:0005886"(plasma membrane)|go:"GO:0007339"(binding of sperm to zona pellucida)|go:"GO:0009566"(fertilization)|go:"GO:0030317"(flagellated sperm motility)|go:"GO:0044853"(plasma membrane raft)|go:"GO:0046658"(anchored component of plasma membrane)|go:"GO:1901317"(regulation of flagellated sperm motility)|interpro:IPR016054(Ly-6 antigen / uPA receptor -like)|rcsb pdb:7BPR|reactome:R-HSA-163125|refseq:NP_001123483.1|refseq:NP_113639.4 refseq:NP_001005353.1|refseq:NP_037542.1|refseq:NP_982289.1|ensembl:ENSG00000162433(gene)|ensembl:ENST00000327299(transcript)|ensembl:ENST00000395334(transcript)|ensembl:ENST00000545314(transcript)|go:"GO:0001889"(liver development)|go:"GO:0002082"(regulation of oxidative phosphorylation)|go:"GO:0004017"(adenylate kinase activity)|go:"GO:0004550"(nucleoside diphosphate kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005525"(GTP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0006165"(nucleoside diphosphate phosphorylation)|go:"GO:0007420"(brain development)|go:"GO:0009142"(nucleoside triphosphate biosynthetic process)|go:"GO:0015949"(nucleobase-containing small molecule interconversion)|go:"GO:0042493"|go:"GO:0046033"(AMP metabolic process)|go:"GO:0046034"(ATP metabolic process)|go:"GO:0046039"(GTP metabolic process)|go:"GO:0046899"(nucleoside triphosphate adenylate kinase activity)|go:"GO:0050145"(nucleoside monophosphate kinase activity)|go:"GO:0071456"(cellular response to hypoxia)|go:"GO:2001169"(regulation of ATP biosynthetic process)|interpro:IPR000850(Adenylate kinase)|interpro:IPR006259(Adenylate kinase, subfamily)|interpro:IPR007862(Adenylate kinase, zinc-finger lid region)|interpro:IPR027417|interpro:IPR028585|interpro:IPR028586|interpro:IPR033690|interpro:IPR036193|rcsb pdb:2AR7|rcsb pdb:2BBW|rcsb pdb:3NDP|reactome:R-HSA-499943|go:"GO:0006172"(ADP biosynthetic process) - - - figure legend:Supp Table S4 and Supp Fig. S3|comment:"Coimmunoprecipitation with 34ED229 (T2) anti-TEX101 antibody"|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-testis)|taxid:9606(Homo sapiens) - 2020/03/24 2020/06/18 rogid:ZE4tXTFi7lUCcIbCL4KHzY3a6xM9606 rogid:Yt5oLpkD4mw2eCmEbLox3W3R2hw9606 rigid:2wTqH12DHkSLcixvnxiJPZhqAc0 false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9BY14 uniprotkb:P42224 intact:EBI-12549378|ensembl:ENSP00000472769|uniprotkb:Q7L5R2|uniprotkb:Q9BPY7 intact:EBI-1057697|uniprotkb:Q53S88|uniprotkb:Q53XW4|uniprotkb:B2RCA0|uniprotkb:Q9UDL5|uniprotkb:A8K989|uniprotkb:D2KFR8|uniprotkb:Q68D00|uniprotkb:D3DPI7|ensembl:ENSP00000354394|ensembl:ENSP00000386244|ensembl:ENSP00000388240|ensembl:ENSP00000438703 psi-mi:tx101_human(display_long)|uniprotkb:TEX101(gene name)|psi-mi:TEX101(display_short)|uniprotkb:Cell surface receptor NYD-SP8(gene name synonym)|uniprotkb:SGRG(gene name synonym)|uniprotkb:Scleroderma-associated autoantigen(gene name synonym)|uniprotkb:Spermatogenesis-related gene protein(gene name synonym)|uniprotkb:UNQ867/PRO1884(orf name) psi-mi:stat1_human(display_long)|uniprotkb:STAT1(gene name)|psi-mi:STAT1(display_short)|uniprotkb:Transcription factor ISGF-3 components p91/p84(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Schiza et al. (2018) imex:IM-28077|pubmed:30097533 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-25504841|imex:IM-28077-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000131126(gene)|ensembl:ENST00000598265(transcript)|go:"GO:0001669"(acrosomal vesicle)|go:"GO:0002080"(acrosomal membrane)|go:"GO:0005576"(extracellular region)|go:"GO:0005886"(plasma membrane)|go:"GO:0007339"(binding of sperm to zona pellucida)|go:"GO:0009566"(fertilization)|go:"GO:0030317"(flagellated sperm motility)|go:"GO:0044853"(plasma membrane raft)|go:"GO:0046658"(anchored component of plasma membrane)|go:"GO:1901317"(regulation of flagellated sperm motility)|interpro:IPR016054(Ly-6 antigen / uPA receptor -like)|rcsb pdb:7BPR|reactome:R-HSA-163125|refseq:NP_001123483.1|refseq:NP_113639.4 refseq:NP_009330.1|refseq:NP_644671.1|rcsb pdb:1YVL|rcsb pdb:2KA6|rcsb pdb:3WWT|reactome:R-HSA-1059683|reactome:R-HSA-1169408|reactome:R-HSA-1433557|reactome:R-HSA-1839117|reactome:R-HSA-186763|reactome:R-HSA-6785807|reactome:R-HSA-877300|reactome:R-HSA-877312|reactome:R-HSA-8854691|reactome:R-HSA-8939902|reactome:R-HSA-8984722|reactome:R-HSA-8985947|reactome:R-HSA-9013508|reactome:R-HSA-9020956|reactome:R-HSA-9020958|reactome:R-HSA-909733|rcsb pdb:1BF5|reactome:R-HSA-9670439|reactome:R-HSA-9673767|reactome:R-HSA-9673770|reactome:R-HSA-9674555|reactome:R-HSA-9705462|reactome:R-HSA-982772|reactome:R-HSA-912694|refseq:XP_006712781.1|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005164"(tumor necrosis factor receptor binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006952"(defense response)|go:"GO:0007259"(receptor signaling pathway via JAK-STAT)|go:"GO:0007584"(response to nutrient)|go:"GO:0008015"(blood circulation)|go:"GO:0009612"(response to mechanical stimulus)|go:"GO:0010742"(macrophage derived foam cell differentiation)|go:"GO:0016525"(negative regulation of angiogenesis)|go:"GO:0016922"(nuclear receptor binding)|ensembl:ENSG00000115415(gene)|ensembl:ENST00000361099(transcript)|ensembl:ENST00000409465(transcript)|ensembl:ENST00000415035(transcript)|ensembl:ENST00000540176(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000979"(RNA polymerase II core promoter sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001937"(negative regulation of endothelial cell proliferation)|go:"GO:0002053"(positive regulation of mesenchymal cell proliferation)|go:"GO:0002230"(positive regulation of defense response to virus by host)|go:"GO:0003340"(negative regulation of mesenchymal to epithelial transition involved in metanephros morphogenesis)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0042493"|go:"GO:0042542"(response to hydrogen peroxide)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0043124"(negative regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043434"(response to peptide hormone)|go:"GO:0044389"(ubiquitin-like protein ligase binding)|go:"GO:0045296"(cadherin binding)|go:"GO:0045648"(positive regulation of erythrocyte differentiation)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0072162"(metanephric mesenchymal cell differentiation)|go:"GO:0072308"(negative regulation of metanephric nephron tubule epithelial cell differentiation)|go:"GO:0140297"(DNA-binding transcription factor binding)|go:"GO:1990841"(promoter-specific chromatin binding)|interpro:IPR000980(SH2 motif)|interpro:IPR001217(STAT transcription factor, core)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|interpro:IPR008967(p53-like transcription factor, DNA-binding)|go:"GO:0046725"(negative regulation by virus of viral protein levels in host cell)|interpro:IPR012345(STAT transcription factor, DNA-binding, subdomain)|interpro:IPR013799(STAT transcription factor, protein interaction)|interpro:IPR013800(STAT transcription factor, all-alpha)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0048661"(positive regulation of smooth muscle cell proliferation)|go:"GO:0051591"(response to cAMP)|go:"GO:0051607"(defense response to virus)|go:"GO:0051721"(protein phosphatase 2A binding)|go:"GO:0051770"(positive regulation of nitric-oxide synthase biosynthetic process)|go:"GO:0060333"(interferon-gamma-mediated signaling pathway)|go:"GO:0060337"(type I interferon signaling pathway)|go:"GO:0061326"(renal tubule development)|go:"GO:0070106"(interleukin-27-mediated signaling pathway)|go:"GO:0071346"(cellular response to interferon-gamma)|go:"GO:0071407"(cellular response to organic cyclic compound)|interpro:IPR013801(STAT transcription factor, DNA-binding)|interpro:IPR015988(STAT transcription factor, coiled coil)|interpro:IPR022752|go:"GO:0072136"(metanephric mesenchymal cell proliferation involved in metanephros development)|interpro:IPR035859|interpro:IPR036535|interpro:IPR036860|interpro:IPR038295|mint:P42224|go:"GO:0019221"(cytokine-mediated signaling pathway)|go:"GO:0019899"(enzyme binding)|go:"GO:0030424"(axon)|go:"GO:0030425"(dendrite)|go:"GO:0031730"(CCR5 chemokine receptor binding)|go:"GO:0032727"(positive regulation of interferon-alpha production)|go:"GO:0032869"(cellular response to insulin stimulus)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033209"(tumor necrosis factor-mediated signaling pathway)|go:"GO:0034097"(response to cytokine)|go:"GO:0035035"(histone acetyltransferase binding)|go:"GO:0035456"(response to interferon-beta)|go:"GO:0035458"(cellular response to interferon-beta)|go:"GO:0042127"(regulation of cell population proliferation)|go:"GO:0042393"(histone binding)|dip:DIP-46140N - - - figure legend:Supp Table S4 and Supp Fig. S3|comment:"Coimmunoprecipitation with 34ED229 (T2) anti-TEX101 antibody"|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-testis)|taxid:9606(Homo sapiens) - 2020/03/24 2020/06/18 rogid:ZE4tXTFi7lUCcIbCL4KHzY3a6xM9606 rogid:a2ZnhdFZkctbjaXLpsYNJ3q5Cv49606 rigid:2wTqH12DHkSLcixvnxiJPZhqAc0 false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9BY14 uniprotkb:P12235 intact:EBI-12549378|ensembl:ENSP00000472769|uniprotkb:Q7L5R2|uniprotkb:Q9BPY7 intact:EBI-359074|uniprotkb:D3DP59|ensembl:ENSP00000281456 psi-mi:tx101_human(display_long)|uniprotkb:TEX101(gene name)|psi-mi:TEX101(display_short)|uniprotkb:Cell surface receptor NYD-SP8(gene name synonym)|uniprotkb:SGRG(gene name synonym)|uniprotkb:Scleroderma-associated autoantigen(gene name synonym)|uniprotkb:Spermatogenesis-related gene protein(gene name synonym)|uniprotkb:UNQ867/PRO1884(orf name) psi-mi:adt1_human(display_long)|uniprotkb:SLC25A4(gene name)|psi-mi:SLC25A4(display_short)|uniprotkb:ANT1(gene name synonym)|uniprotkb:Adenine nucleotide translocator 1(gene name synonym)|uniprotkb:ADP,ATP carrier protein 1(gene name synonym)|uniprotkb:Solute carrier family 25 member 4(gene name synonym)|uniprotkb:ADP,ATP carrier protein, heart/skeletal muscle isoform T1(gene name synonym)|uniprotkb:AAC1(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Schiza et al. (2018) imex:IM-28077|pubmed:30097533 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-25504841|imex:IM-28077-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000131126(gene)|ensembl:ENST00000598265(transcript)|go:"GO:0001669"(acrosomal vesicle)|go:"GO:0002080"(acrosomal membrane)|go:"GO:0005576"(extracellular region)|go:"GO:0005886"(plasma membrane)|go:"GO:0007339"(binding of sperm to zona pellucida)|go:"GO:0009566"(fertilization)|go:"GO:0030317"(flagellated sperm motility)|go:"GO:0044853"(plasma membrane raft)|go:"GO:0046658"(anchored component of plasma membrane)|go:"GO:1901317"(regulation of flagellated sperm motility)|interpro:IPR016054(Ly-6 antigen / uPA receptor -like)|rcsb pdb:7BPR|reactome:R-HSA-163125|refseq:NP_001123483.1|refseq:NP_113639.4 refseq:NP_001142.2|ensembl:ENST00000281456(transcript)|go:"GO:0000002"(mitochondrial genome maintenance)|go:"GO:0005471"("ATP:ADP antiporter activity")|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005757"(mitochondrial permeability transition pore complex)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006091"(generation of precursor metabolites and energy)|go:"GO:0008637"(apoptotic mitochondrial changes)|go:"GO:0015078"(proton transmembrane transporter activity)|go:"GO:0015207"(adenine transmembrane transporter activity)|go:"GO:0015866"(ADP transport)|ensembl:ENSG00000151729(gene)|go:"GO:0016020"(membrane)|go:"GO:0017077"(oxidative phosphorylation uncoupler activity)|go:"GO:0032592"(integral component of mitochondrial membrane)|go:"GO:0046902"(regulation of mitochondrial membrane permeability)|go:"GO:0060546"(negative regulation of necroptotic process)|go:"GO:0140021"(mitochondrial ADP transmembrane transport)|go:"GO:1901526"(positive regulation of mitophagy)|go:"GO:1990544"(mitochondrial ATP transmembrane transport)|go:"GO:1990845"(adaptive thermogenesis)|interpro:IPR002067(Mitochondrial carrier protein)|interpro:IPR002113(Adenine nucleotide translocator 1)|interpro:IPR018108|interpro:IPR023395|mint:P12235|reactome:R-HSA-1268020|reactome:R-HSA-180897|reactome:R-HSA-83936|dip:DIP-33116N - - - figure legend:Supp Table S4 and Supp Fig. S3|comment:"Coimmunoprecipitation with 34ED229 (T2) anti-TEX101 antibody"|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-testis)|taxid:9606(Homo sapiens) - 2020/03/24 2020/06/18 rogid:ZE4tXTFi7lUCcIbCL4KHzY3a6xM9606 rogid:vs4XIUUUypcIHR9Lz4j1buDAnjM9606 rigid:2wTqH12DHkSLcixvnxiJPZhqAc0 false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9BY14 uniprotkb:P17813 intact:EBI-12549378|ensembl:ENSP00000472769|uniprotkb:Q7L5R2|uniprotkb:Q9BPY7 intact:EBI-2834630|uniprotkb:Q5T9C0|uniprotkb:Q14248|uniprotkb:Q14926|ensembl:ENSP00000362299 psi-mi:tx101_human(display_long)|uniprotkb:TEX101(gene name)|psi-mi:TEX101(display_short)|uniprotkb:Cell surface receptor NYD-SP8(gene name synonym)|uniprotkb:SGRG(gene name synonym)|uniprotkb:Scleroderma-associated autoantigen(gene name synonym)|uniprotkb:Spermatogenesis-related gene protein(gene name synonym)|uniprotkb:UNQ867/PRO1884(orf name) psi-mi:egln_human(display_long)|uniprotkb:ENG(gene name)|psi-mi:ENG(display_short)|uniprotkb:END(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Schiza et al. (2018) imex:IM-28077|pubmed:30097533 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-25504841|imex:IM-28077-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000131126(gene)|ensembl:ENST00000598265(transcript)|go:"GO:0001669"(acrosomal vesicle)|go:"GO:0002080"(acrosomal membrane)|go:"GO:0005576"(extracellular region)|go:"GO:0005886"(plasma membrane)|go:"GO:0007339"(binding of sperm to zona pellucida)|go:"GO:0009566"(fertilization)|go:"GO:0030317"(flagellated sperm motility)|go:"GO:0044853"(plasma membrane raft)|go:"GO:0046658"(anchored component of plasma membrane)|go:"GO:1901317"(regulation of flagellated sperm motility)|interpro:IPR016054(Ly-6 antigen / uPA receptor -like)|rcsb pdb:7BPR|reactome:R-HSA-163125|refseq:NP_001123483.1|refseq:NP_113639.4 go:"GO:0005615"(extracellular space)|go:"GO:0005886"(plasma membrane)|go:"GO:0005925"(focal adhesion)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0007155"(cell adhesion)|go:"GO:0007179"(transforming growth factor beta receptor signaling pathway)|go:"GO:0009897"(external side of plasma membrane)|go:"GO:0009986"(cell surface)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0010862"(positive regulation of pathway-restricted SMAD protein phosphorylation)|go:"GO:0015026"(coreceptor activity)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016477"(cell migration)|go:"GO:0016604"(nuclear body)|go:"GO:0017015"(regulation of transforming growth factor beta receptor signaling pathway)|go:"GO:0022009"(central nervous system vasculogenesis)|go:"GO:0022617"(extracellular matrix disassembly)|go:"GO:0030155"(regulation of cell adhesion)|go:"GO:0005539"(glycosaminoglycan binding)|go:"GO:0030336"(negative regulation of cell migration)|go:"GO:0030509"(BMP signaling pathway)|go:"GO:0030512"(negative regulation of transforming growth factor beta receptor signaling pathway)|go:"GO:0030513"(positive regulation of BMP signaling pathway)|go:"GO:0031953"(negative regulation of protein autophosphorylation)|go:"GO:0031960"(response to corticosteroid)|go:"GO:0032967"(positive regulation of collagen biosynthetic process)|go:"GO:0034713"(type I transforming growth factor beta receptor binding)|go:"GO:0035912"(dorsal aorta morphogenesis)|go:"GO:0042060"(wound healing)|go:"GO:0042127"(regulation of cell population proliferation)|go:"GO:0042325"(regulation of phosphorylation)|go:"GO:0042493"|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043235"(receptor complex)|go:"GO:0045766"(positive regulation of angiogenesis)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048185"(activin binding)|go:"GO:0048745"(smooth muscle tissue development)|go:"GO:0048844"(artery morphogenesis)|go:"GO:0048845"(venous blood vessel morphogenesis)|go:"GO:0048870"(cell motility)|go:"GO:0050431"(transforming growth factor beta binding)|go:"GO:0051001"(negative regulation of nitric-oxide synthase activity)|go:"GO:0051897"(positive regulation of protein kinase B signaling)|go:"GO:0055009"(atrial cardiac muscle tissue morphogenesis)|go:"GO:0060326"(cell chemotaxis)|go:"GO:0060348"(bone development)|go:"GO:0060394"(negative regulation of pathway-restricted SMAD protein phosphorylation)|go:"GO:0070278"(extracellular matrix constituent secretion)|go:"GO:0070483"(detection of hypoxia)|go:"GO:0071260"(cellular response to mechanical stimulus)|go:"GO:0072563"(endothelial microparticle)|go:"GO:0097084"(vascular associated smooth muscle cell development)|go:"GO:1905007"(positive regulation of epithelial to mesenchymal transition involved in endocardial cushion formation)|go:"GO:1905065"(positive regulation of vascular associated smooth muscle cell differentiation)|go:"GO:1905222"(atrioventricular canal morphogenesis)|interpro:IPR001507(Endoglin/CD105 antigen)|mint:P17813|rcsb pdb:5HZV|rcsb pdb:5HZW|rcsb pdb:5I04|ensembl:ENSG00000106991(gene)|ensembl:ENST00000373203(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0001525"(angiogenesis)|go:"GO:0001569"(branching involved in blood vessel morphogenesis)|go:"GO:0001666"(response to hypoxia)|go:"GO:0001837"(epithelial to mesenchymal transition)|go:"GO:0001934"(positive regulation of protein phosphorylation)|go:"GO:0001937"(negative regulation of endothelial cell proliferation)|go:"GO:0001947"(heart looping)|go:"GO:0003084"(positive regulation of systemic arterial blood pressure)|go:"GO:0003148"(outflow tract septum morphogenesis)|go:"GO:0003198"(epithelial to mesenchymal transition involved in endocardial cushion formation)|go:"GO:0003203"(endocardial cushion morphogenesis)|go:"GO:0003208"(cardiac ventricle morphogenesis)|go:"GO:0003209"(cardiac atrium morphogenesis)|go:"GO:0003222"(ventricular trabecula myocardium morphogenesis)|go:"GO:0003273"(cell migration involved in endocardial cushion formation)|go:"GO:0004888"(transmembrane signaling receptor activity)|go:"GO:0005024"(transforming growth factor beta-activated receptor activity)|go:"GO:0005114"(type II transforming growth factor beta receptor binding)|go:"GO:0005534"(galactose binding)|go:"GO:0001570"(vasculogenesis)|refseq:NP_000109.1|refseq:NP_001108225.1|refseq:NP_001265067.1|dip:DIP-6246N - - - figure legend:Supp Table S4 and Supp Fig. S3|comment:"Coimmunoprecipitation with 34ED229 (T2) anti-TEX101 antibody"|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-testis)|taxid:9606(Homo sapiens) - 2020/03/24 2020/06/18 rogid:ZE4tXTFi7lUCcIbCL4KHzY3a6xM9606 rogid:6+7wUY8XztGVcjgbUlGaRjvBIK89606 rigid:2wTqH12DHkSLcixvnxiJPZhqAc0 false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9BY14 uniprotkb:Q14108 intact:EBI-12549378|ensembl:ENSP00000472769|uniprotkb:Q7L5R2|uniprotkb:Q9BPY7 intact:EBI-1564650|uniprotkb:Q53Y63|uniprotkb:B4DKD8|uniprotkb:E7EM68|ensembl:ENSP00000264896 psi-mi:tx101_human(display_long)|uniprotkb:TEX101(gene name)|psi-mi:TEX101(display_short)|uniprotkb:Cell surface receptor NYD-SP8(gene name synonym)|uniprotkb:SGRG(gene name synonym)|uniprotkb:Scleroderma-associated autoantigen(gene name synonym)|uniprotkb:Spermatogenesis-related gene protein(gene name synonym)|uniprotkb:UNQ867/PRO1884(orf name) psi-mi:scrb2_human(display_long)|uniprotkb:Lysosome membrane protein II(gene name synonym)|uniprotkb:Scavenger receptor class B member 2(gene name synonym)|uniprotkb:85 kDa lysosomal membrane sialoglycoprotein(gene name synonym)|uniprotkb:CD36 antigen-like 2(gene name synonym)|uniprotkb:SCARB2(gene name)|psi-mi:SCARB2(display_short)|uniprotkb:CD36L2(gene name synonym)|uniprotkb:LIMPII(gene name synonym)|uniprotkb:LIMP2(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Schiza et al. (2018) imex:IM-28077|pubmed:30097533 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-25504841|imex:IM-28077-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000131126(gene)|ensembl:ENST00000598265(transcript)|go:"GO:0001669"(acrosomal vesicle)|go:"GO:0002080"(acrosomal membrane)|go:"GO:0005576"(extracellular region)|go:"GO:0005886"(plasma membrane)|go:"GO:0007339"(binding of sperm to zona pellucida)|go:"GO:0009566"(fertilization)|go:"GO:0030317"(flagellated sperm motility)|go:"GO:0044853"(plasma membrane raft)|go:"GO:0046658"(anchored component of plasma membrane)|go:"GO:1901317"(regulation of flagellated sperm motility)|interpro:IPR016054(Ly-6 antigen / uPA receptor -like)|rcsb pdb:7BPR|reactome:R-HSA-163125|refseq:NP_001123483.1|refseq:NP_113639.4 refseq:NP_001191184.1|refseq:NP_005497.1|ensembl:ENSG00000138760(gene)|ensembl:ENST00000264896(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001618"(virus receptor activity)|go:"GO:0001786"(phosphatidylserine binding)|go:"GO:0004888"(transmembrane signaling receptor activity)|go:"GO:0005044"(scavenger receptor activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005886"(plasma membrane)|go:"GO:0005925"(focal adhesion)|go:"GO:0006622"(protein targeting to lysosome)|go:"GO:0006898"(receptor-mediated endocytosis)|go:"GO:0007605"(sensory perception of sound)|go:"GO:0010008"(endosome membrane)|go:"GO:0010467"(gene expression)|go:"GO:0010976"(positive regulation of neuron projection development)|go:"GO:0015485"(cholesterol binding)|go:"GO:0015917"(aminophospholipid transport)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0019899"(enzyme binding)|go:"GO:0030666"(endocytic vesicle membrane)|go:"GO:0030669"(clathrin-coated endocytic vesicle membrane)|go:"GO:0031210"(phosphatidylcholine binding)|go:"GO:0031902"(late endosome membrane)|go:"GO:0038024"(cargo receptor activity)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043202"(lysosomal lumen)|go:"GO:0043471"(regulation of cellular carbohydrate catabolic process)|go:"GO:0051087"(chaperone binding)|go:"GO:0070062"(extracellular exosome)|go:"GO:1904978"(regulation of endosome organization)|go:"GO:1905123"(regulation of glucosylceramidase activity)|go:"GO:1905671"(regulation of lysosome organization)|interpro:IPR002159(CD36 antigen)|interpro:IPR005429(Lysosome membrane protein II)|mint:Q14108|rcsb pdb:4F7B|rcsb pdb:4Q4B|rcsb pdb:4Q4F|rcsb pdb:4TVZ|rcsb pdb:4TW0|rcsb pdb:4TW2|rcsb pdb:5UPH|rcsb pdb:5XBM|rcsb pdb:6I2K|reactome:R-HSA-8856825|reactome:R-HSA-8856828 - - - figure legend:Supp Table S4 and Supp Fig. S3|comment:"Coimmunoprecipitation with 34ED229 (T2) anti-TEX101 antibody"|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-testis)|taxid:9606(Homo sapiens) - 2020/03/24 2020/06/18 rogid:ZE4tXTFi7lUCcIbCL4KHzY3a6xM9606 rogid:FXyG5dJv7OqGjSgl5slIqNxUqoI9606 rigid:2wTqH12DHkSLcixvnxiJPZhqAc0 false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9BY14 uniprotkb:O95340 intact:EBI-12549378|ensembl:ENSP00000472769|uniprotkb:Q7L5R2|uniprotkb:Q9BPY7 intact:EBI-1053912|uniprotkb:Q9BZL2|uniprotkb:Q9P0G6|uniprotkb:Q9UHM1|uniprotkb:Q9UKD3|uniprotkb:Q9UP30|ensembl:ENSP00000354436 psi-mi:tx101_human(display_long)|uniprotkb:TEX101(gene name)|psi-mi:TEX101(display_short)|uniprotkb:Cell surface receptor NYD-SP8(gene name synonym)|uniprotkb:SGRG(gene name synonym)|uniprotkb:Scleroderma-associated autoantigen(gene name synonym)|uniprotkb:Spermatogenesis-related gene protein(gene name synonym)|uniprotkb:UNQ867/PRO1884(orf name) psi-mi:paps2_human(display_long)|uniprotkb:Sulfurylase kinase 2(gene name synonym)|uniprotkb:PAPSS2(gene name)|psi-mi:PAPSS2(display_short)|uniprotkb:ATPSK2(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Schiza et al. (2018) imex:IM-28077|pubmed:30097533 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-25504841|imex:IM-28077-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000131126(gene)|ensembl:ENST00000598265(transcript)|go:"GO:0001669"(acrosomal vesicle)|go:"GO:0002080"(acrosomal membrane)|go:"GO:0005576"(extracellular region)|go:"GO:0005886"(plasma membrane)|go:"GO:0007339"(binding of sperm to zona pellucida)|go:"GO:0009566"(fertilization)|go:"GO:0030317"(flagellated sperm motility)|go:"GO:0044853"(plasma membrane raft)|go:"GO:0046658"(anchored component of plasma membrane)|go:"GO:1901317"(regulation of flagellated sperm motility)|interpro:IPR016054(Ly-6 antigen / uPA receptor -like)|rcsb pdb:7BPR|reactome:R-HSA-163125|refseq:NP_001123483.1|refseq:NP_113639.4 refseq:NP_001015880.1|refseq:NP_004661.2|ensembl:ENSG00000198682(gene)|ensembl:ENST00000361175(transcript)|go:"GO:0000103"(sulfate assimilation)|go:"GO:0001501"(skeletal system development)|go:"GO:0004020"(adenylylsulfate kinase activity)|go:"GO:0004781"("sulfate adenylyltransferase (ATP) activity")|go:"GO:0005524"(ATP binding)|go:"GO:0005829"(cytosol)|go:"GO:0016779"(nucleotidyltransferase activity)|go:"GO:0050428"(3'-phosphoadenosine 5'-phosphosulfate biosynthetic process)|interpro:IPR002650(ATP-sulphurylase)|interpro:IPR002891(Adenylylsulphate kinase, C-terminal)|interpro:IPR014729(Rossmann-like alpha/beta/alpha sandwich fold)|interpro:IPR015947(PUA-like)|interpro:IPR024951|interpro:IPR025980|interpro:IPR027417|rcsb pdb:2AX4|reactome:R-HSA-174362|reactome:R-HSA-2408550|reactome:R-HSA-3560796 - - - figure legend:Supp Table S4 and Supp Fig. S3|comment:"Coimmunoprecipitation with 34ED229 (T2) anti-TEX101 antibody"|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-testis)|taxid:9606(Homo sapiens) - 2020/03/24 2020/06/18 rogid:ZE4tXTFi7lUCcIbCL4KHzY3a6xM9606 rogid:0t32V/kBypJ6YKgkyxAxC3RGmeU9606 rigid:2wTqH12DHkSLcixvnxiJPZhqAc0 false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9BY14 uniprotkb:Q15019 intact:EBI-12549378|ensembl:ENSP00000472769|uniprotkb:Q7L5R2|uniprotkb:Q9BPY7 intact:EBI-741220|intact:EBI-28986019|ensembl:ENSP00000353157|ensembl:ENSP00000375832|ensembl:ENSP00000375834|ensembl:ENSP00000385172|uniprotkb:Q14132|uniprotkb:Q8IUK9|uniprotkb:Q96CB0|uniprotkb:B4DGE8|uniprotkb:Q53QU3 psi-mi:tx101_human(display_long)|uniprotkb:TEX101(gene name)|psi-mi:TEX101(display_short)|uniprotkb:Cell surface receptor NYD-SP8(gene name synonym)|uniprotkb:SGRG(gene name synonym)|uniprotkb:Scleroderma-associated autoantigen(gene name synonym)|uniprotkb:Spermatogenesis-related gene protein(gene name synonym)|uniprotkb:UNQ867/PRO1884(orf name) psi-mi:sept2_human(display_long)|uniprotkb:SEPTIN2(gene name)|psi-mi:SEPTIN2(display_short)|uniprotkb:DIFF6(gene name synonym)|uniprotkb:KIAA0158(gene name synonym)|uniprotkb:NEDD5(gene name synonym)|uniprotkb:Neural precursor cell expressed developmentally down-regulated protein 5(gene name synonym)|uniprotkb:SEPT2(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Schiza et al. (2018) imex:IM-28077|pubmed:30097533 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-25504841|imex:IM-28077-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000131126(gene)|ensembl:ENST00000598265(transcript)|go:"GO:0001669"(acrosomal vesicle)|go:"GO:0002080"(acrosomal membrane)|go:"GO:0005576"(extracellular region)|go:"GO:0005886"(plasma membrane)|go:"GO:0007339"(binding of sperm to zona pellucida)|go:"GO:0009566"(fertilization)|go:"GO:0030317"(flagellated sperm motility)|go:"GO:0044853"(plasma membrane raft)|go:"GO:0046658"(anchored component of plasma membrane)|go:"GO:1901317"(regulation of flagellated sperm motility)|interpro:IPR016054(Ly-6 antigen / uPA receptor -like)|rcsb pdb:7BPR|reactome:R-HSA-163125|refseq:NP_001123483.1|refseq:NP_113639.4 refseq:NP_001269901.1|refseq:NP_001269902.1|ensembl:ENSG00000168385(gene)|ensembl:ENST00000360051(transcript)|ensembl:ENST00000391971(transcript)|ensembl:ENST00000391973(transcript)|ensembl:ENST00000402092(transcript)|go:"GO:0000145"(exocyst)|go:"GO:0000776"(kinetochore)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005819"(spindle)|go:"GO:0005886"(plasma membrane)|go:"GO:0005930"(axoneme)|go:"GO:0005940"(septin ring)|go:"GO:0007224"(smoothened signaling pathway)|go:"GO:0007283"(spermatogenesis)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0017157"(regulation of exocytosis)|go:"GO:0030496"(midbody)|go:"GO:0031105"(septin complex)|go:"GO:0031175"(neuron projection development)|go:"GO:0032153"(cell division site)|go:"GO:0032154"(cleavage furrow)|go:"GO:0032391"(photoreceptor connecting cilium)|go:"GO:0034613"(cellular protein localization)|go:"GO:0042802"(identical protein binding)|go:"GO:0045171"(intercellular bridge)|go:"GO:0045296"(cadherin binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0060170"(ciliary membrane)|go:"GO:0060271"(cilium assembly)|go:"GO:0061640"(cytoskeleton-dependent cytokinesis)|go:"GO:0070062"(extracellular exosome)|go:"GO:0097227"(sperm annulus)|go:"GO:0097730"(non-motile cilium)|interpro:IPR008113(Septin 2)|interpro:IPR016491(Septin)|interpro:IPR027417|interpro:IPR030379|mint:Q15019|rcsb pdb:2QA5|rcsb pdb:2QAG|rcsb pdb:2QNR|rcsb pdb:6UPA|rcsb pdb:6UPQ|rcsb pdb:6UPR|reactome:R-HSA-5620912|refseq:NP_001008491.1|refseq:NP_001008492.1|refseq:NP_004395.1|refseq:NP_006146.1|refseq:XP_016859694.1|refseq:XP_016859695.1|refseq:NP_001307958.1|refseq:NP_001307959.1|refseq:NP_001307960.1|refseq:NP_001307961.1|refseq:NP_001307962.1|refseq:NP_001307963.1|refseq:NP_001307964.1|ensembl:ENSP00000353157|ensembl:ENSP00000375832|ensembl:ENSP00000375834|ensembl:ENST00000401990|ensembl:ENSP00000385109|ensembl:ENSP00000385172|ensembl:ENST00000616972|ensembl:ENSP00000479861|dip:DIP-38220N - - crc64:12CCBBE30806F92F figure legend:Supp Table S4 and Supp Fig. S3|comment:"Coimmunoprecipitation with 34ED229 (T2) anti-TEX101 antibody"|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-testis)|taxid:9606(Homo sapiens) - 2020/03/24 2020/06/18 rogid:ZE4tXTFi7lUCcIbCL4KHzY3a6xM9606 rogid:H0Us8GtPe2XuXlOYXC0DX79kB/49606 rigid:2wTqH12DHkSLcixvnxiJPZhqAc0 false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9BY14 uniprotkb:P47895 intact:EBI-12549378|ensembl:ENSP00000472769|uniprotkb:Q7L5R2|uniprotkb:Q9BPY7 intact:EBI-21573752|uniprotkb:Q6NT64|ensembl:ENSP00000332256 psi-mi:tx101_human(display_long)|uniprotkb:TEX101(gene name)|psi-mi:TEX101(display_short)|uniprotkb:Cell surface receptor NYD-SP8(gene name synonym)|uniprotkb:SGRG(gene name synonym)|uniprotkb:Scleroderma-associated autoantigen(gene name synonym)|uniprotkb:Spermatogenesis-related gene protein(gene name synonym)|uniprotkb:UNQ867/PRO1884(orf name) psi-mi:al1a3_human(display_long)|uniprotkb:Aldehyde dehydrogenase 6(gene name synonym)|uniprotkb:Retinaldehyde dehydrogenase 3(gene name synonym)|uniprotkb:ALDH1A3(gene name)|psi-mi:ALDH1A3(display_short)|uniprotkb:ALDH6(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Schiza et al. (2018) imex:IM-28077|pubmed:30097533 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-25504841|imex:IM-28077-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000131126(gene)|ensembl:ENST00000598265(transcript)|go:"GO:0001669"(acrosomal vesicle)|go:"GO:0002080"(acrosomal membrane)|go:"GO:0005576"(extracellular region)|go:"GO:0005886"(plasma membrane)|go:"GO:0007339"(binding of sperm to zona pellucida)|go:"GO:0009566"(fertilization)|go:"GO:0030317"(flagellated sperm motility)|go:"GO:0044853"(plasma membrane raft)|go:"GO:0046658"(anchored component of plasma membrane)|go:"GO:1901317"(regulation of flagellated sperm motility)|interpro:IPR016054(Ly-6 antigen / uPA receptor -like)|rcsb pdb:7BPR|reactome:R-HSA-163125|refseq:NP_001123483.1|refseq:NP_113639.4 refseq:NP_000684.2|refseq:NP_001280744.1|go:"GO:0004030"("aldehyde dehydrogenase [NAD(P)+] activity")|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0007626"(locomotory behavior)|go:"GO:0021768"(nucleus accumbens development)|go:"GO:0031076"(embryonic camera-type eye development)|go:"GO:0042472"(inner ear morphogenesis)|go:"GO:0042572"(retinol metabolic process)|go:"GO:0042573"(retinoic acid metabolic process)|go:"GO:0042574"(retinal metabolic process)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0048048"(embryonic eye morphogenesis)|go:"GO:0050885"(neuromuscular process controlling balance)|go:"GO:0051289"(protein homotetramerization)|go:"GO:0060013"(righting reflex)|go:"GO:0060166"(olfactory pit development)|go:"GO:0060324"(face development)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070324"(thyroid hormone binding)|go:"GO:0070384"(Harderian gland development)|go:"GO:0070403"(NAD+ binding)|interpro:IPR015590(Aldehyde dehydrogenase)|interpro:IPR016160(Aldehyde dehydrogenase, conserved site)|interpro:IPR016161(Aldehyde/histidinol dehydrogenase)|interpro:IPR016162(Aldehyde dehydrogenase, N-terminal)|interpro:IPR016163(Aldehyde dehydrogenase, C-terminal)|interpro:IPR029510|rcsb pdb:5FHZ|rcsb pdb:6S6W|rcsb pdb:6TE5|rcsb pdb:6TGW|rcsb pdb:6TRY|rcsb pdb:7A6Q|reactome:R-HSA-5365859|go:"GO:0004029"("aldehyde dehydrogenase (NAD+) activity")|ensembl:ENSG00000184254(gene)|ensembl:ENST00000329841(transcript)|go:"GO:0001758"(retinal dehydrogenase activity)|go:"GO:0002072"(optic cup morphogenesis involved in camera-type eye development)|go:"GO:0002138"(retinoic acid biosynthetic process) - - - figure legend:Supp Table S4 and Supp Fig. S3|comment:"Coimmunoprecipitation with 34ED229 (T2) anti-TEX101 antibody"|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-testis)|taxid:9606(Homo sapiens) - 2020/03/24 2020/06/18 rogid:ZE4tXTFi7lUCcIbCL4KHzY3a6xM9606 rogid:IXQ56uxVqM92z+jRKUeqVGfwImM9606 rigid:2wTqH12DHkSLcixvnxiJPZhqAc0 false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9BY14 uniprotkb:P62805 intact:EBI-12549378|ensembl:ENSP00000472769|uniprotkb:Q7L5R2|uniprotkb:Q9BPY7 intact:EBI-302023|ensembl:ENSP00000244537|ensembl:ENSP00000347168|ensembl:ENSP00000350767|ensembl:ENSP00000366974|ensembl:ENSP00000366956|ensembl:ENSP00000462667|ensembl:ENSP00000367034|ensembl:ENSP00000478519|ensembl:ENSP00000478786|ensembl:ENSP00000443017|ensembl:ENSP00000462355|ensembl:ENSP00000479106|ensembl:ENSP00000479461|uniprotkb:A2VCL0|uniprotkb:P02304|uniprotkb:P02305|uniprotkb:Q6DRA9|uniprotkb:Q6FGB8|uniprotkb:Q6NWP7|ensembl:ENSP00000479794|ensembl:ENSP00000480960|ensembl:ENSP00000481343|ensembl:ENSP00000481486|ensembl:ENSP00000481507|ensembl:ENSP00000482412|ensembl:ENSP00000484789|ensembl:ENSP00000489319|ensembl:ENSP00000489567 psi-mi:tx101_human(display_long)|uniprotkb:TEX101(gene name)|psi-mi:TEX101(display_short)|uniprotkb:Cell surface receptor NYD-SP8(gene name synonym)|uniprotkb:SGRG(gene name synonym)|uniprotkb:Scleroderma-associated autoantigen(gene name synonym)|uniprotkb:Spermatogenesis-related gene protein(gene name synonym)|uniprotkb:UNQ867/PRO1884(orf name) psi-mi:h4_human(display_long)|uniprotkb:H4-16(gene name)|psi-mi:H4-16(display_short)|uniprotkb:H4C1(gene name)|psi-mi:H4C1(display_short)|uniprotkb:H4C11(gene name)|psi-mi:H4C11(display_short)|uniprotkb:H4C12(gene name)|psi-mi:H4C12(display_short)|uniprotkb:H4C13(gene name)|psi-mi:H4C13(display_short)|uniprotkb:H4C14(gene name)|psi-mi:H4C14(display_short)|uniprotkb:H4C15(gene name)|psi-mi:H4C15(display_short)|uniprotkb:H4C2(gene name)|psi-mi:H4C2(display_short)|uniprotkb:H4C3(gene name)|psi-mi:H4C3(display_short)|uniprotkb:H4C4(gene name)|psi-mi:H4C4(display_short)|uniprotkb:H4C5(gene name)|psi-mi:H4C5(display_short)|uniprotkb:H4C6(gene name)|psi-mi:H4C6(display_short)|uniprotkb:H4C8(gene name)|psi-mi:H4C8(display_short)|uniprotkb:H4C9(gene name)|psi-mi:H4C9(display_short)|uniprotkb:H4/A(gene name synonym)|uniprotkb:H4/B(gene name synonym)|uniprotkb:H4/C(gene name synonym)|uniprotkb:H4/D(gene name synonym)|uniprotkb:H4/E(gene name synonym)|uniprotkb:H4/G(gene name synonym)|uniprotkb:H4/H(gene name synonym)|uniprotkb:H4/I(gene name synonym)|uniprotkb:H4/J(gene name synonym)|uniprotkb:H4/K(gene name synonym)|uniprotkb:H4/M(gene name synonym)|uniprotkb:H4/N(gene name synonym)|uniprotkb:H4/O(gene name synonym)|uniprotkb:H4F2(gene name synonym)|uniprotkb:H4FA(gene name synonym)|uniprotkb:H4FB(gene name synonym)|uniprotkb:H4FC(gene name synonym)|uniprotkb:H4FD(gene name synonym)|uniprotkb:H4FE(gene name synonym)|uniprotkb:H4FG(gene name synonym)|uniprotkb:H4FH(gene name synonym)|uniprotkb:H4FI(gene name synonym)|uniprotkb:H4FJ(gene name synonym)|uniprotkb:H4FK(gene name synonym)|uniprotkb:H4FM(gene name synonym)|uniprotkb:H4FN(gene name synonym)|uniprotkb:H4FO(gene name synonym)|uniprotkb:HIST1H4A(gene name synonym)|uniprotkb:HIST1H4B(gene name synonym)|uniprotkb:HIST1H4C(gene name synonym)|uniprotkb:HIST1H4D(gene name synonym)|uniprotkb:HIST1H4E(gene name synonym)|uniprotkb:HIST1H4F(gene name synonym)|uniprotkb:HIST1H4H(gene name synonym)|uniprotkb:HIST1H4I(gene name synonym)|uniprotkb:HIST1H4J(gene name synonym)|uniprotkb:HIST1H4K(gene name synonym)|uniprotkb:HIST1H4L(gene name synonym)|uniprotkb:HIST2H4(gene name synonym)|uniprotkb:HIST2H4A(gene name synonym)|uniprotkb:HIST2H4B(gene name synonym)|uniprotkb:HIST4H4(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Schiza et al. (2018) imex:IM-28077|pubmed:30097533 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-25504841|imex:IM-28077-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000131126(gene)|ensembl:ENST00000598265(transcript)|go:"GO:0001669"(acrosomal vesicle)|go:"GO:0002080"(acrosomal membrane)|go:"GO:0005576"(extracellular region)|go:"GO:0005886"(plasma membrane)|go:"GO:0007339"(binding of sperm to zona pellucida)|go:"GO:0009566"(fertilization)|go:"GO:0030317"(flagellated sperm motility)|go:"GO:0044853"(plasma membrane raft)|go:"GO:0046658"(anchored component of plasma membrane)|go:"GO:1901317"(regulation of flagellated sperm motility)|interpro:IPR016054(Ly-6 antigen / uPA receptor -like)|rcsb pdb:7BPR|reactome:R-HSA-163125|refseq:NP_001123483.1|refseq:NP_113639.4 ensembl:ENSG00000197061(gene)|ensembl:ENSG00000276180(gene)|ensembl:ENSG00000197238(gene)|ensembl:ENSG00000276966(gene)|ensembl:ENSG00000277157(gene)|ensembl:ENSG00000270276(gene)|ensembl:ENSG00000197837(gene)|ensembl:ENSG00000270882(gene)|ensembl:ENSG00000278637(gene)|ensembl:ENSG00000273542(gene)|ensembl:ENSG00000274618(gene)|ensembl:ENSG00000278705(gene)|ensembl:ENSG00000275126(gene)|ensembl:ENSG00000158406(gene)|dip:DIP-33079N|ensembl:ENST00000244537(transcript)|ensembl:ENST00000355057(transcript)|ensembl:ENST00000358064(transcript)|ensembl:ENST00000377727(transcript)|ensembl:ENST00000377745(transcript)|ensembl:ENST00000377803(transcript)|ensembl:ENST00000539745(transcript)|ensembl:ENST00000578186(transcript)|ensembl:ENST00000579512(transcript)|ensembl:ENST00000611927(transcript)|ensembl:ENST00000612061(transcript)|ensembl:ENST00000613412(transcript)|ensembl:ENST00000614247(transcript)|ensembl:ENST00000614272(transcript)|ensembl:ENST00000615164(transcript)|ensembl:ENST00000615353(transcript)|ensembl:ENST00000617569(transcript)|ensembl:ENST00000618193(transcript)|ensembl:ENST00000618305(transcript)|ensembl:ENST00000621520(transcript)|ensembl:ENST00000634560(transcript)|ensembl:ENST00000634956(transcript)|go:"GO:0000228"(nuclear chromosome)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0000786"(nucleosome)|go:"GO:0003677"(DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006334"(nucleosome assembly)|go:"GO:0006335"(DNA replication-dependent chromatin assembly)|go:"GO:0006336"(DNA replication-independent chromatin assembly)|go:"GO:0006352"(DNA-templated transcription, initiation)|go:"GO:0016020"(membrane)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0032200"(telomere organization)|go:"GO:0032991"(protein-containing complex)|go:"GO:0045653"(negative regulation of megakaryocyte differentiation)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0005576"(extracellular region)|go:"GO:0070062"(extracellular exosome)|interpro:IPR001951(Histone H4)|interpro:IPR004823("TATA box binding protein associated factor (TAF)")|rcsb pdb:3AZE|rcsb pdb:3AZF|rcsb pdb:3AZG|rcsb pdb:3AZH|rcsb pdb:3AZI|rcsb pdb:3AYW|rcsb pdb:3AZJ|rcsb pdb:3AZK|rcsb pdb:3AZL|rcsb pdb:3AZM|rcsb pdb:3AZN|rcsb pdb:3CFS|rcsb pdb:3CFV|rcsb pdb:3F9W|rcsb pdb:3F9X|rcsb pdb:3F9Y|rcsb pdb:3F9Z|rcsb pdb:3IJ1|rcsb pdb:3JPX|rcsb pdb:3NQJ|rcsb pdb:3NQU|rcsb pdb:3O36|rcsb pdb:3QBY|rcsb pdb:3QZS|rcsb pdb:3QZT|rcsb pdb:3QZV|rcsb pdb:3R45|rcsb pdb:3UVW|rcsb pdb:3UVX|rcsb pdb:3UVY|rcsb pdb:3UW9|rcsb pdb:3W96|rcsb pdb:3W97|rcsb pdb:3W98|rcsb pdb:3W99|rcsb pdb:3WA9|rcsb pdb:3WAA|rcsb pdb:3WKJ|rcsb pdb:3WTP|rcsb pdb:3X1S|rcsb pdb:3X1T|rcsb pdb:3X1U|rcsb pdb:3X1V|rcsb pdb:4GQB|rcsb pdb:4H9N|rcsb pdb:4H9O|rcsb pdb:4H9P|rcsb pdb:4H9Q|rcsb pdb:4H9R|rcsb pdb:4H9S|rcsb pdb:4HGA|rcsb pdb:4M38|rcsb pdb:4N3W|rcsb pdb:4N4F|rcsb pdb:4QUT|rcsb pdb:4QUU|rcsb pdb:4QYD|rcsb pdb:4U9W|rcsb pdb:4YM5|rcsb pdb:4YM6|rcsb pdb:4YY6|rcsb pdb:4YYD|rcsb pdb:4YYG|rcsb pdb:4YYH|rcsb pdb:4YYI|rcsb pdb:4YYJ|rcsb pdb:4YYK|rcsb pdb:4YYM|rcsb pdb:4YYN|rcsb pdb:4Z2M|rcsb pdb:4Z5T|rcsb pdb:5AV5|rcsb pdb:5AV6|rcsb pdb:5AV8|rcsb pdb:5AV9|rcsb pdb:5AVB|rcsb pdb:5AVC|rcsb pdb:5AY8|rcsb pdb:5B0Y|rcsb pdb:5B0Z|rcsb pdb:5B24|rcsb pdb:5B2I|rcsb pdb:5B2J|rcsb pdb:5B31|rcsb pdb:5B32|rcsb pdb:5B33|rcsb pdb:5B40|rcsb pdb:5BNV|rcsb pdb:5BNX|rcsb pdb:5BO0|rcsb pdb:5C3I|rcsb pdb:5CPI|interpro:IPR019809|interpro:IPR035425|mint:P62805|rcsb pdb:1ZKK|rcsb pdb:2BQZ|rcsb pdb:2CV5|rcsb pdb:2IG0|rcsb pdb:2KWN|rcsb pdb:2KWO|rcsb pdb:2LVM|rcsb pdb:2QQS|rcsb pdb:2RJE|rcsb pdb:2RNY|interpro:IPR009072(Histone-fold)|rcsb pdb:2RS9|rcsb pdb:3A6N|rcsb pdb:3AFA|rcsb pdb:3AN2|rcsb pdb:3AV1|rcsb pdb:3AV2|rcsb pdb:5GT3|rcsb pdb:5GTC|rcsb pdb:5GXQ|rcsb pdb:5JA4|rcsb pdb:5JRG|rcsb pdb:5KDM|rcsb pdb:5TEG|rcsb pdb:5X7X|rcsb pdb:5XF3|rcsb pdb:5XF4|rcsb pdb:5XF5|rcsb pdb:5Y0C|rcsb pdb:5Y0D|rcsb pdb:5YE3|rcsb pdb:5YE4|rcsb pdb:5Z23|rcsb pdb:5Z30|rcsb pdb:5ZBX|rcsb pdb:5ZGC|rcsb pdb:5CPJ|rcsb pdb:6A5L|rcsb pdb:6A5O|rcsb pdb:5CPK|rcsb pdb:6A5P|rcsb pdb:5FA5|rcsb pdb:6A5R|rcsb pdb:6A5T|rcsb pdb:6A5U|rcsb pdb:6ACP|rcsb pdb:6BUZ|rcsb pdb:6C0W|rcsb pdb:6E0C|rcsb pdb:6E0P|rcsb pdb:6FML|rcsb pdb:6HKT|rcsb pdb:6HTS|rcsb pdb:6INQ|rcsb pdb:6IR9|rcsb pdb:6J4W|rcsb pdb:6J4X|rcsb pdb:6J4Y|rcsb pdb:6J4Z|rcsb pdb:6J50|rcsb pdb:6J51|rcsb pdb:6JOU|rcsb pdb:6JR0|rcsb pdb:6JR1|rcsb pdb:6K1I|rcsb pdb:6K1J|rcsb pdb:6K1K|rcsb pdb:6KE9|rcsb pdb:6KVD|rcsb pdb:6KXV|rcsb pdb:6L49|rcsb pdb:6L4A|rcsb pdb:6L9H|rcsb pdb:6L9Z|rcsb pdb:6LA2|rcsb pdb:6LA8|rcsb pdb:6LA9|rcsb pdb:6LAB|rcsb pdb:6LE9|rcsb pdb:6LER|rcsb pdb:6M3V|rcsb pdb:6M44|rcsb pdb:6M4D|rcsb pdb:5FFW|rcsb pdb:5FWE|rcsb pdb:5GSE|rcsb pdb:5GSU|rcsb pdb:5GT0|rcsb pdb:6M4G|rcsb pdb:6M4H|rcsb pdb:6MLC|rcsb pdb:6MUO|rcsb pdb:6MUP|rcsb pdb:6O1D|rcsb pdb:6R0C|rcsb pdb:6R8Y|rcsb pdb:6R8Z|rcsb pdb:6R90|rcsb pdb:6R91|refseq:NP_001029249.1|refseq:NP_003486.1|refseq:NP_003529.1|refseq:NP_003530.1|refseq:NP_003531.1|refseq:NP_003532.1|refseq:NP_003533.1|refseq:NP_003534.1|refseq:NP_003535.1|refseq:NP_003536.1|refseq:NP_003537.1|refseq:NP_003539.1|rcsb pdb:6R92|rcsb pdb:6R93|rcsb pdb:6R94|rcsb pdb:6RNY|rcsb pdb:6RXS|rcsb pdb:6SE0|rcsb pdb:6SE6|rcsb pdb:6SEE|rcsb pdb:6SEF|rcsb pdb:6SEG|rcsb pdb:6T79|rcsb pdb:6T7A|rcsb pdb:6T7B|rcsb pdb:6T7C|rcsb pdb:6T7D|rcsb pdb:6T90|rcsb pdb:6T93|rcsb pdb:6UPK|rcsb pdb:6UPL|rcsb pdb:6USJ|rcsb pdb:6V2K|rcsb pdb:6V92|rcsb pdb:6VO5|rcsb pdb:6X59|rcsb pdb:6X5A|rcsb pdb:6XJD|rcsb pdb:6Y5D|rcsb pdb:6YOV|rcsb pdb:7A08|rcsb pdb:7BWD|rcsb pdb:7BXT|rcsb pdb:7BY0|rcsb pdb:7C0M|rcsb pdb:7CCQ|rcsb pdb:7CCR|rcsb pdb:7CIZ|rcsb pdb:7CJ0|rcsb pdb:7D1Z|rcsb pdb:7D20|rcsb pdb:7DBP|rcsb pdb:7JO9|rcsb pdb:7JOA|rcsb pdb:7JZV|rcsb pdb:7K5X|rcsb pdb:7K5Y|rcsb pdb:7K60|rcsb pdb:7K61|rcsb pdb:7K63|rcsb pdb:7LMK|rcsb pdb:7LMM|rcsb pdb:7LYC|reactome:R-HSA-110328|reactome:R-HSA-110329|reactome:R-HSA-110330|reactome:R-HSA-110331|reactome:R-HSA-1221632|reactome:R-HSA-171306|reactome:R-HSA-1912408|reactome:R-HSA-201722|reactome:R-HSA-212300|reactome:R-HSA-2299718|reactome:R-HSA-2559580|reactome:R-HSA-2559582|reactome:R-HSA-2559586|reactome:R-HSA-3214815|reactome:R-HSA-3214841|reactome:R-HSA-3214842|reactome:R-HSA-3214847|reactome:R-HSA-3214858|reactome:R-HSA-427359|reactome:R-HSA-427389|reactome:R-HSA-427413|reactome:R-HSA-4551638|reactome:R-HSA-5250924|reactome:R-HSA-5334118|reactome:R-HSA-5578749|reactome:R-HSA-5617472|reactome:R-HSA-5625886|reactome:R-HSA-5693565|refseq:NP_068803.1|refseq:NP_778224.1|reactome:R-HSA-5693571|reactome:R-HSA-5693607|reactome:R-HSA-606279|reactome:R-HSA-69473|reactome:R-HSA-73728|reactome:R-HSA-73772|reactome:R-HSA-8936459|reactome:R-HSA-8939236|reactome:R-HSA-9018519|reactome:R-HSA-912446|reactome:R-HSA-9609690|reactome:R-HSA-9610379|reactome:R-HSA-9616222|reactome:R-HSA-9670095|reactome:R-HSA-9710421|reactome:R-HSA-977225 - - - figure legend:Supp Table S4 and Supp Fig. S3|comment:"Coimmunoprecipitation with 34ED229 (T2) anti-TEX101 antibody"|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-testis)|taxid:9606(Homo sapiens) - 2020/03/24 2020/06/18 rogid:ZE4tXTFi7lUCcIbCL4KHzY3a6xM9606 rogid:LZSfhrpw0PcDREEoJ1UMkBvnUfA9606 rigid:2wTqH12DHkSLcixvnxiJPZhqAc0 false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9BY14 uniprotkb:O15143 intact:EBI-12549378|ensembl:ENSP00000472769|uniprotkb:Q7L5R2|uniprotkb:Q9BPY7 intact:EBI-1044647|uniprotkb:Q9BU00|ensembl:ENSP00000388802|ensembl:ENSP00000389631|ensembl:ENSP00000398110|ensembl:ENSP00000403211|ensembl:ENSP00000410238|ensembl:ENSP00000494033|ensembl:ENSP00000496599 psi-mi:tx101_human(display_long)|uniprotkb:TEX101(gene name)|psi-mi:TEX101(display_short)|uniprotkb:Cell surface receptor NYD-SP8(gene name synonym)|uniprotkb:SGRG(gene name synonym)|uniprotkb:Scleroderma-associated autoantigen(gene name synonym)|uniprotkb:Spermatogenesis-related gene protein(gene name synonym)|uniprotkb:UNQ867/PRO1884(orf name) psi-mi:arc1b_human(display_long)|uniprotkb:Arp2/3 complex 41 kDa subunit(gene name synonym)|uniprotkb:p41-ARC(gene name synonym)|uniprotkb:ARPC1B(gene name)|psi-mi:ARPC1B(display_short)|uniprotkb:ARC41(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Schiza et al. (2018) imex:IM-28077|pubmed:30097533 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-25504841|imex:IM-28077-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000131126(gene)|ensembl:ENST00000598265(transcript)|go:"GO:0001669"(acrosomal vesicle)|go:"GO:0002080"(acrosomal membrane)|go:"GO:0005576"(extracellular region)|go:"GO:0005886"(plasma membrane)|go:"GO:0007339"(binding of sperm to zona pellucida)|go:"GO:0009566"(fertilization)|go:"GO:0030317"(flagellated sperm motility)|go:"GO:0044853"(plasma membrane raft)|go:"GO:0046658"(anchored component of plasma membrane)|go:"GO:1901317"(regulation of flagellated sperm motility)|interpro:IPR016054(Ly-6 antigen / uPA receptor -like)|rcsb pdb:7BPR|reactome:R-HSA-163125|refseq:NP_001123483.1|refseq:NP_113639.4 refseq:NP_005711.1|ensembl:ENSG00000130429(gene)|ensembl:ENST00000427217(transcript)|ensembl:ENST00000431816(transcript)|ensembl:ENST00000451682(transcript)|ensembl:ENST00000455009(transcript)|ensembl:ENST00000458033(transcript)|ensembl:ENST00000645391(transcript)|ensembl:ENST00000646101(transcript)|go:"GO:0003779"(actin binding)|go:"GO:0005200"(structural constituent of cytoskeleton)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0005885"(Arp2/3 protein complex)|go:"GO:0005925"(focal adhesion)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0032355"(response to estradiol)|go:"GO:0034314"(Arp2/3 complex-mediated actin nucleation)|go:"GO:0036284"(tubulobulbar complex)|go:"GO:0043627"(response to estrogen)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0070062"(extracellular exosome)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR017383(Actin-related protein 2/3 complex, subunit 1)|interpro:IPR030141|interpro:IPR036322|mint:O15143|rcsb pdb:6UHC|rcsb pdb:6YW6|reactome:R-HSA-2029482|reactome:R-HSA-3928662|reactome:R-HSA-5663213|reactome:R-HSA-9664422|refseq:XP_006715888.1|refseq:XP_006715889.1|dip:DIP-41254N - - - figure legend:Supp Table S4 and Supp Fig. S3|comment:"Coimmunoprecipitation with 34ED229 (T2) anti-TEX101 antibody"|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-testis)|taxid:9606(Homo sapiens) - 2020/03/24 2020/06/18 rogid:ZE4tXTFi7lUCcIbCL4KHzY3a6xM9606 rogid:sx7R5hirSnqoXyOlW6ltrpNjUIs9606 rigid:2wTqH12DHkSLcixvnxiJPZhqAc0 false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9BY14 uniprotkb:P35613 intact:EBI-12549378|ensembl:ENSP00000472769|uniprotkb:Q7L5R2|uniprotkb:Q9BPY7 intact:EBI-750709|uniprotkb:Q7Z796|uniprotkb:Q8IZL7|intact:EBI-2553051|uniprotkb:A6NJW1|uniprotkb:D3YLG5|ensembl:ENSP00000333769 psi-mi:tx101_human(display_long)|uniprotkb:TEX101(gene name)|psi-mi:TEX101(display_short)|uniprotkb:Cell surface receptor NYD-SP8(gene name synonym)|uniprotkb:SGRG(gene name synonym)|uniprotkb:Scleroderma-associated autoantigen(gene name synonym)|uniprotkb:Spermatogenesis-related gene protein(gene name synonym)|uniprotkb:UNQ867/PRO1884(orf name) psi-mi:basi_human(display_long)|uniprotkb:Leukocyte activation antigen M6(gene name synonym)|uniprotkb:Collagenase stimulatory factor(gene name synonym)|uniprotkb:Extracellular matrix metalloproteinase inducer(gene name synonym)|uniprotkb:5F7(gene name synonym)|uniprotkb:Tumor cell-derived collagenase stimulatory factor(gene name synonym)|uniprotkb:OK blood group antigen(gene name synonym)|uniprotkb:BSG(gene name)|psi-mi:BSG(display_short)|uniprotkb:UNQ6505/PRO21383(orf name)|uniprotkb:Hepatoma-associated antigen(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Schiza et al. (2018) imex:IM-28077|pubmed:30097533 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-25504841|imex:IM-28077-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000131126(gene)|ensembl:ENST00000598265(transcript)|go:"GO:0001669"(acrosomal vesicle)|go:"GO:0002080"(acrosomal membrane)|go:"GO:0005576"(extracellular region)|go:"GO:0005886"(plasma membrane)|go:"GO:0007339"(binding of sperm to zona pellucida)|go:"GO:0009566"(fertilization)|go:"GO:0030317"(flagellated sperm motility)|go:"GO:0044853"(plasma membrane raft)|go:"GO:0046658"(anchored component of plasma membrane)|go:"GO:1901317"(regulation of flagellated sperm motility)|interpro:IPR016054(Ly-6 antigen / uPA receptor -like)|rcsb pdb:7BPR|reactome:R-HSA-163125|refseq:NP_001123483.1|refseq:NP_113639.4 refseq:NP_001719.2|refseq:NP_940991.1|refseq:NP_940993.1|refseq:NP_001309172.1|refseq:NP_940992.1|refseq:XP_016882662.1|dip:DIP-50310N|ensembl:ENSG00000172270(gene)|ensembl:ENST00000333511(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001525"(angiogenesis)|go:"GO:0001618"(virus receptor activity)|go:"GO:0001750"(photoreceptor outer segment)|go:"GO:0001917"(photoreceptor inner segment)|go:"GO:0002080"(acrosomal membrane)|go:"GO:0003407"(neural retina development)|go:"GO:0005537"(mannose binding)|go:"GO:0005739"(mitochondrion)|go:"GO:0005768"(endosome)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0005925"(focal adhesion)|go:"GO:0007156"(homophilic cell adhesion via plasma membrane adhesion molecules)|go:"GO:0007166"(cell surface receptor signaling pathway)|go:"GO:0007411"(axon guidance)|go:"GO:0007566"(embryo implantation)|go:"GO:0010575"(positive regulation of vascular endothelial growth factor production)|go:"GO:0010595"(positive regulation of endothelial cell migration)|go:"GO:0016020"(membrane)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0030424"(axon)|go:"GO:0030593"(neutrophil chemotaxis)|go:"GO:0032755"(positive regulation of interleukin-6 production)|go:"GO:0038023"(signaling receptor activity)|go:"GO:0042383"(sarcolemma)|go:"GO:0042470"(melanosome)|go:"GO:0042475"(odontogenesis of dentin-containing tooth)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0043434"(response to peptide hormone)|go:"GO:0045121"(membrane raft)|go:"GO:0045296"(cadherin binding)|go:"GO:0045494"(photoreceptor cell maintenance)|go:"GO:0046598"(positive regulation of viral entry into host cell)|go:"GO:0046689"(response to mercury ion)|go:"GO:0046697"(decidualization)|go:"GO:0051591"(response to cAMP)|go:"GO:0061154"(endothelial tube morphogenesis)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070593"(dendrite self-avoidance)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0098632"(cell-cell adhesion mediator activity)|go:"GO:1904466"(positive regulation of matrix metallopeptidase secretion)|interpro:IPR003598(Immunoglobulin subtype 2)|interpro:IPR003599(Immunoglobulin subtype)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR036179|interpro:IPR043204|interpro:IPR044157|mint:P35613|rcsb pdb:3B5H|rcsb pdb:3I84|rcsb pdb:3I85|rcsb pdb:3QQN|rcsb pdb:4U0Q|rcsb pdb:5X0T|rcsb pdb:5XF0|rcsb pdb:6LYY|rcsb pdb:6LZ0|rcsb pdb:7CKO|rcsb pdb:7CKR|rcsb pdb:7DA5|reactome:R-HSA-1474228|reactome:R-HSA-210991|reactome:R-HSA-216083|reactome:R-HSA-433692|reactome:R-HSA-5619070|reactome:R-HSA-70268|rcsb pdb:3QR2 - - - figure legend:Supp Table S4 and Supp Fig. S3|comment:"Coimmunoprecipitation with 34ED229 (T2) anti-TEX101 antibody"|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-testis)|taxid:9606(Homo sapiens) - 2020/03/24 2020/06/18 rogid:ZE4tXTFi7lUCcIbCL4KHzY3a6xM9606 rogid:jVbDR+TKBzTjXoxR4At6XQg59ZA9606 rigid:2wTqH12DHkSLcixvnxiJPZhqAc0 false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9BY14 uniprotkb:P05556 intact:EBI-12549378|ensembl:ENSP00000472769|uniprotkb:Q7L5R2|uniprotkb:Q9BPY7 intact:EBI-703066|intact:EBI-4289597|ensembl:ENSP00000303351|ensembl:ENSP00000379350|ensembl:ENSP00000398029|ensembl:ENSP00000404546|ensembl:ENSP00000502882|ensembl:ENSP00000503546|ensembl:ENSP00000503916|ensembl:ENSP00000504205|ensembl:ENSP00000504444|uniprotkb:Q7Z3V1|uniprotkb:Q8WUM6|uniprotkb:P78466|uniprotkb:P78467|uniprotkb:Q13089|uniprotkb:Q13090|uniprotkb:Q13091|uniprotkb:Q13212|uniprotkb:Q14622|uniprotkb:Q14647|uniprotkb:A8K6N2|uniprotkb:Q29RW2|uniprotkb:D3DRX9|uniprotkb:D3DRY3|uniprotkb:D3DRY4|uniprotkb:D3DRY5 psi-mi:tx101_human(display_long)|uniprotkb:TEX101(gene name)|psi-mi:TEX101(display_short)|uniprotkb:Cell surface receptor NYD-SP8(gene name synonym)|uniprotkb:SGRG(gene name synonym)|uniprotkb:Scleroderma-associated autoantigen(gene name synonym)|uniprotkb:Spermatogenesis-related gene protein(gene name synonym)|uniprotkb:UNQ867/PRO1884(orf name) psi-mi:itb1_human(display_long)|uniprotkb:Fibronectin receptor subunit beta(gene name synonym)|uniprotkb:VLA-4 subunit beta(gene name synonym)|uniprotkb:ITGB1(gene name)|psi-mi:ITGB1(display_short)|uniprotkb:FNRB(gene name synonym)|uniprotkb:MDF2(gene name synonym)|uniprotkb:MSK12(gene name synonym)|uniprotkb:Glycoprotein IIa(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Schiza et al. (2018) imex:IM-28077|pubmed:30097533 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-25504841|imex:IM-28077-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000131126(gene)|ensembl:ENST00000598265(transcript)|go:"GO:0001669"(acrosomal vesicle)|go:"GO:0002080"(acrosomal membrane)|go:"GO:0005576"(extracellular region)|go:"GO:0005886"(plasma membrane)|go:"GO:0007339"(binding of sperm to zona pellucida)|go:"GO:0009566"(fertilization)|go:"GO:0030317"(flagellated sperm motility)|go:"GO:0044853"(plasma membrane raft)|go:"GO:0046658"(anchored component of plasma membrane)|go:"GO:1901317"(regulation of flagellated sperm motility)|interpro:IPR016054(Ly-6 antigen / uPA receptor -like)|rcsb pdb:7BPR|reactome:R-HSA-163125|refseq:NP_001123483.1|refseq:NP_113639.4 go:"GO:0001618"(virus receptor activity)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0001708"(cell fate specification)|go:"GO:0001726"(ruffle)|go:"GO:0001968"(fibronectin binding)|go:"GO:0002020"(protease binding)|go:"GO:0002042"(cell migration involved in sprouting angiogenesis)|go:"GO:0003779"(actin binding)|go:"GO:0005178"(integrin binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0005925"(focal adhesion)|go:"GO:0006909"(phagocytosis)|go:"GO:0006968"(cellular defense response)|go:"GO:0007155"(cell adhesion)|go:"GO:0007156"(homophilic cell adhesion via plasma membrane adhesion molecules)|go:"GO:0007159"(leukocyte cell-cell adhesion)|go:"GO:0007160"(cell-matrix adhesion)|go:"GO:0007161"(calcium-independent cell-matrix adhesion)|go:"GO:0007229"(integrin-mediated signaling pathway)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0008354"(germ cell migration)|go:"GO:0008542"(visual learning)|go:"GO:0009897"(external side of plasma membrane)|go:"GO:0009986"(cell surface)|go:"GO:0010008"(endosome membrane)|go:"GO:0010710"(regulation of collagen catabolic process)|go:"GO:0010763"(positive regulation of fibroblast migration)|go:"GO:0014704"(intercalated disc)|go:"GO:0015026"(coreceptor activity)|go:"GO:0016020"(membrane)|go:"GO:0016477"(cell migration)|go:"GO:0021943"(formation of radial glial scaffolds)|go:"GO:0023035"(CD40 signaling pathway)|go:"GO:0030027"(lamellipodium)|go:"GO:0030030"(cell projection organization)|go:"GO:0030032"(lamellipodium assembly)|go:"GO:0030175"(filopodium)|go:"GO:0030183"(B cell differentiation)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0031589"(cell-substrate adhesion)|go:"GO:0031594"(neuromuscular junction)|go:"GO:0031623"(receptor internalization)|go:"GO:0032154"(cleavage furrow)|go:"GO:0032587"(ruffle membrane)|go:"GO:0033627"(cell adhesion mediated by integrin)|go:"GO:0033631"(cell-cell adhesion mediated by integrin)|go:"GO:0034113"(heterotypic cell-cell adhesion)|go:"GO:0034665"(integrin alpha1-beta1 complex)|go:"GO:0034666"(integrin alpha2-beta1 complex)|go:"GO:0034667"(integrin alpha3-beta1 complex)|go:"GO:0034668"(integrin alpha4-beta1 complex)|go:"GO:0034674"(integrin alpha5-beta1 complex)|go:"GO:0034677"(integrin alpha7-beta1 complex)|go:"GO:0034678"(integrin alpha8-beta1 complex)|go:"GO:0034680"(integrin alpha10-beta1 complex)|go:"GO:0034681"(integrin alpha11-beta1 complex)|go:"GO:0035024"(negative regulation of Rho protein signal transduction)|go:"GO:0035633"(maintenance of blood-brain barrier)|go:"GO:0035748"(myelin sheath abaxonal region)|go:"GO:0042383"(sarcolemma)|go:"GO:0042470"(melanosome)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043197"(dendritic spine)|go:"GO:0043235"(receptor complex)|go:"GO:0043236"(laminin binding)|go:"GO:0043547"(positive regulation of GTPase activity)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045121"(membrane raft)|go:"GO:0045214"(sarcomere organization)|go:"GO:0045296"(cadherin binding)|go:"GO:0045596"(negative regulation of cell differentiation)|go:"GO:0045766"(positive regulation of angiogenesis)|go:"GO:0046872"(metal ion binding)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0048333"(mesodermal cell differentiation)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0048675"(axon extension)|go:"GO:0048813"(dendrite morphogenesis)|go:"GO:0050839"(cell adhesion molecule binding)|go:"GO:0050901"(leukocyte tethering or rolling)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0051897"(positive regulation of protein kinase B signaling)|go:"GO:0051951"(positive regulation of glutamate uptake involved in transmission of nerve impulse)|go:"GO:0055007"(cardiac muscle cell differentiation)|go:"GO:0055037"(recycling endosome)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071404"(cellular response to low-density lipoprotein particle stimulus)|go:"GO:0071711"(basement membrane organization)|go:"GO:0090303"(positive regulation of wound healing)|go:"GO:0097386"(glial cell projection)|go:"GO:0098639"(collagen binding involved in cell-matrix adhesion)|go:"GO:0098685"(Schaffer collateral - CA1 synapse)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099699"(integral component of synaptic membrane)|go:"GO:0150003"(regulation of spontaneous synaptic transmission)|go:"GO:0150103"(reactive gliosis)|go:"GO:1901979"(regulation of inward rectifier potassium channel activity)|go:"GO:1903078"(positive regulation of protein localization to plasma membrane)|go:"GO:1990782"(protein tyrosine kinase binding)|go:"GO:2000273"(positive regulation of signaling receptor activity)|go:"GO:2000811"(negative regulation of anoikis)|interpro:IPR002369(Integrin beta subunit, N-terminal)|interpro:IPR012896(Integrin beta subunit, tail)|interpro:IPR013111(EGF, extracellular)|interpro:IPR014836(Integrin beta subunit, cytoplasmic)|interpro:IPR015812(Integrin beta subunit)|interpro:IPR016201(Plexin-like fold)|interpro:IPR027071|interpro:IPR032695|interpro:IPR033760|interpro:IPR036349|interpro:IPR036465|interpro:IPR040622|mint:P05556|rcsb pdb:1K11|rcsb pdb:1LHA|rcsb pdb:3G9W|rcsb pdb:3T9K|rcsb pdb:3VI3|rcsb pdb:3VI4|rcsb pdb:4DX9|rcsb pdb:4WJK|rcsb pdb:4WK0|rcsb pdb:4WK2|rcsb pdb:4WK4|rcsb pdb:7CEB|rcsb pdb:7CEC|rcsb pdb:7NWL|reactome:R-HSA-1566948|reactome:R-HSA-1566977|reactome:R-HSA-198933|ensembl:ENSG00000150093(gene)|ensembl:ENST00000302278(transcript)|ensembl:ENST00000396033(transcript)|ensembl:ENST00000417122(transcript)|ensembl:ENST00000437302(transcript)|ensembl:ENST00000677999(transcript)|ensembl:ENST00000678701(transcript)|ensembl:ENST00000678943(transcript)|ensembl:ENST00000678952(transcript)|ensembl:ENST00000678989(transcript)|go:"GO:0000082"(G1/S transition of mitotic cell cycle)|go:"GO:0000132"(establishment of mitotic spindle orientation)|refseq:NP_002202.2|refseq:NP_391988.1|refseq:NP_596867.1|dip:DIP-312N|reactome:R-HSA-202733|reactome:R-HSA-210991|reactome:R-HSA-2129379|reactome:R-HSA-216083|reactome:R-HSA-3000157|reactome:R-HSA-3000170|reactome:R-HSA-3000178|reactome:R-HSA-416700|reactome:R-HSA-445144|reactome:R-HSA-446343|reactome:R-HSA-447041|reactome:R-HSA-5663220|reactome:R-HSA-6785807|reactome:R-HSA-75892|reactome:R-HSA-8874081|reactome:R-HSA-8875513|reactome:R-HSA-9013149|reactome:R-HSA-9013404|reactome:R-HSA-9013408|reactome:R-HSA-9013423|reactome:R-HSA-9609690|reactome:R-HSA-9679191 - - - figure legend:Supp Table S4 and Supp Fig. S3|comment:"Coimmunoprecipitation with 34ED229 (T2) anti-TEX101 antibody"|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-testis)|taxid:9606(Homo sapiens) - 2020/03/24 2020/06/18 rogid:ZE4tXTFi7lUCcIbCL4KHzY3a6xM9606 rogid:FZ+lMRS6Zq07A8Lgmf5C6vEXUgM9606 rigid:2wTqH12DHkSLcixvnxiJPZhqAc0 false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9BY14 uniprotkb:Q8TEX9 intact:EBI-12549378|ensembl:ENSP00000472769|uniprotkb:Q7L5R2|uniprotkb:Q9BPY7 intact:EBI-395967|uniprotkb:Q2NL96|uniprotkb:Q86TZ9|uniprotkb:Q8NCG8|uniprotkb:Q96SJ3|uniprotkb:Q9BTI4|uniprotkb:Q9H5L0|uniprotkb:B2RN95|ensembl:ENSP00000346453|ensembl:ENSP00000494795 psi-mi:tx101_human(display_long)|uniprotkb:TEX101(gene name)|psi-mi:TEX101(display_short)|uniprotkb:Cell surface receptor NYD-SP8(gene name synonym)|uniprotkb:SGRG(gene name synonym)|uniprotkb:Scleroderma-associated autoantigen(gene name synonym)|uniprotkb:Spermatogenesis-related gene protein(gene name synonym)|uniprotkb:UNQ867/PRO1884(orf name) psi-mi:ipo4_human(display_long)|uniprotkb:IPO4(gene name)|psi-mi:IPO4(display_short)|uniprotkb:IMP4B(gene name synonym)|uniprotkb:RANBP4(gene name synonym)|uniprotkb:Importin-4b(gene name synonym)|uniprotkb:Ran-binding protein 4(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Schiza et al. (2018) imex:IM-28077|pubmed:30097533 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-25504841|imex:IM-28077-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000131126(gene)|ensembl:ENST00000598265(transcript)|go:"GO:0001669"(acrosomal vesicle)|go:"GO:0002080"(acrosomal membrane)|go:"GO:0005576"(extracellular region)|go:"GO:0005886"(plasma membrane)|go:"GO:0007339"(binding of sperm to zona pellucida)|go:"GO:0009566"(fertilization)|go:"GO:0030317"(flagellated sperm motility)|go:"GO:0044853"(plasma membrane raft)|go:"GO:0046658"(anchored component of plasma membrane)|go:"GO:1901317"(regulation of flagellated sperm motility)|interpro:IPR016054(Ly-6 antigen / uPA receptor -like)|rcsb pdb:7BPR|reactome:R-HSA-163125|refseq:NP_001123483.1|refseq:NP_113639.4 refseq:NP_078934.3|dip:DIP-32944N|ensembl:ENSG00000196497(gene)|ensembl:ENSG00000285248(gene)|ensembl:ENST00000354464(transcript)|ensembl:ENST00000644546(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006335"(DNA replication-dependent chromatin assembly)|go:"GO:0006336"(DNA replication-independent chromatin assembly)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0008139"(nuclear localization sequence binding)|go:"GO:0016020"(membrane)|go:"GO:0031267"(small GTPase binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0061608"(nuclear import signal receptor activity)|interpro:IPR000357(HEAT)|interpro:IPR001494(Importin-beta, N-terminal)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR021133|interpro:IPR034085|interpro:IPR040122|mint:Q8TEX9|rcsb pdb:5XAH|rcsb pdb:5XBK - - - figure legend:Supp Table S4 and Supp Fig. S3|comment:"Coimmunoprecipitation with 34ED229 (T2) anti-TEX101 antibody"|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-testis)|taxid:9606(Homo sapiens) - 2020/03/24 2020/06/18 rogid:ZE4tXTFi7lUCcIbCL4KHzY3a6xM9606 rogid:PVIcGG3WTf0QmYbS0vvy049EjlQ9606 rigid:2wTqH12DHkSLcixvnxiJPZhqAc0 false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9BY14 uniprotkb:O75155 intact:EBI-12549378|ensembl:ENSP00000472769|uniprotkb:Q7L5R2|uniprotkb:Q9BPY7 intact:EBI-5656182|uniprotkb:B9EGM9|uniprotkb:E9KL24|ensembl:ENSP00000387641 psi-mi:tx101_human(display_long)|uniprotkb:TEX101(gene name)|psi-mi:TEX101(display_short)|uniprotkb:Cell surface receptor NYD-SP8(gene name synonym)|uniprotkb:SGRG(gene name synonym)|uniprotkb:Scleroderma-associated autoantigen(gene name synonym)|uniprotkb:Spermatogenesis-related gene protein(gene name synonym)|uniprotkb:UNQ867/PRO1884(orf name) psi-mi:cand2_human(display_long)|uniprotkb:Cullin-associated and neddylation-dissociated protein 2(gene name synonym)|uniprotkb:KIAA0667(gene name synonym)|uniprotkb:TBP-interacting protein of 120 kDa B(gene name synonym)|uniprotkb:TIP120B(gene name synonym)|uniprotkb:p120 CAND2(gene name synonym)|uniprotkb:CAND2(gene name)|psi-mi:CAND2(display_short)|uniprotkb:Epididymis tissue protein Li 169(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Schiza et al. (2018) imex:IM-28077|pubmed:30097533 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-25504841|imex:IM-28077-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000131126(gene)|ensembl:ENST00000598265(transcript)|go:"GO:0001669"(acrosomal vesicle)|go:"GO:0002080"(acrosomal membrane)|go:"GO:0005576"(extracellular region)|go:"GO:0005886"(plasma membrane)|go:"GO:0007339"(binding of sperm to zona pellucida)|go:"GO:0009566"(fertilization)|go:"GO:0030317"(flagellated sperm motility)|go:"GO:0044853"(plasma membrane raft)|go:"GO:0046658"(anchored component of plasma membrane)|go:"GO:1901317"(regulation of flagellated sperm motility)|interpro:IPR016054(Ly-6 antigen / uPA receptor -like)|rcsb pdb:7BPR|reactome:R-HSA-163125|refseq:NP_001123483.1|refseq:NP_113639.4 refseq:NP_001155971.1|refseq:NP_036430.1|ensembl:ENSG00000144712(gene)|ensembl:ENST00000456430(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0010265"(SCF complex assembly)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0017025"(TBP-class protein binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|interpro:IPR013932("TATA-binding protein interacting (TIP20)")|interpro:IPR016024(Armadillo-type fold)|interpro:IPR039852|mint:O75155 - - - figure legend:Supp Table S4 and Supp Fig. S3|comment:"Coimmunoprecipitation with 34ED229 (T2) anti-TEX101 antibody"|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-testis)|taxid:9606(Homo sapiens) - 2020/03/24 2020/06/18 rogid:ZE4tXTFi7lUCcIbCL4KHzY3a6xM9606 rogid:LKo/B25pZVSPOAE+Yvk/ug1o7xY9606 rigid:2wTqH12DHkSLcixvnxiJPZhqAc0 false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9BY14 uniprotkb:Q13508 intact:EBI-12549378|ensembl:ENSP00000472769|uniprotkb:Q7L5R2|uniprotkb:Q9BPY7 intact:EBI-3904355|uniprotkb:Q96HL1|uniprotkb:Q8WVJ7|uniprotkb:Q6FHT7|uniprotkb:Q53XW3|uniprotkb:Q93069|ensembl:ENSP00000348064 psi-mi:tx101_human(display_long)|uniprotkb:TEX101(gene name)|psi-mi:TEX101(display_short)|uniprotkb:Cell surface receptor NYD-SP8(gene name synonym)|uniprotkb:SGRG(gene name synonym)|uniprotkb:Scleroderma-associated autoantigen(gene name synonym)|uniprotkb:Spermatogenesis-related gene protein(gene name synonym)|uniprotkb:UNQ867/PRO1884(orf name) psi-mi:nar3_human(display_long)|uniprotkb:ART3(gene name)|psi-mi:ART3(display_short)|uniprotkb:TMART(gene name synonym)|uniprotkb:"Mono(ADP-ribosyl)transferase 3"(gene name synonym)|uniprotkb:"NAD(P)(+)--arginine ADP-ribosyltransferase 3"(gene name synonym)|uniprotkb:ADP-ribosyltransferase C2 and C3 toxin-like 3(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Schiza et al. (2018) imex:IM-28077|pubmed:30097533 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-25504841|imex:IM-28077-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000131126(gene)|ensembl:ENST00000598265(transcript)|go:"GO:0001669"(acrosomal vesicle)|go:"GO:0002080"(acrosomal membrane)|go:"GO:0005576"(extracellular region)|go:"GO:0005886"(plasma membrane)|go:"GO:0007339"(binding of sperm to zona pellucida)|go:"GO:0009566"(fertilization)|go:"GO:0030317"(flagellated sperm motility)|go:"GO:0044853"(plasma membrane raft)|go:"GO:0046658"(anchored component of plasma membrane)|go:"GO:1901317"(regulation of flagellated sperm motility)|interpro:IPR016054(Ly-6 antigen / uPA receptor -like)|rcsb pdb:7BPR|reactome:R-HSA-163125|refseq:NP_001123483.1|refseq:NP_113639.4 refseq:NP_001123488.1|refseq:NP_001123489.1|refseq:NP_001170.2|ensembl:ENSG00000156219(gene)|ensembl:ENST00000355810(transcript)|go:"GO:0003950"(NAD+ ADP-ribosyltransferase activity)|go:"GO:0005576"(extracellular region)|go:"GO:0005886"(plasma membrane)|go:"GO:0006471"(protein ADP-ribosylation)|go:"GO:0031225"(anchored component of membrane)|go:"GO:0031226"(intrinsic component of plasma membrane)|go:"GO:0070062"(extracellular exosome)|go:"GO:0106274"(NAD+-protein-arginine ADP-ribosyltransferase activity)|go:"GO:0106275"(NADP+-protein-arginine ADP-ribosyltransferase activity)|interpro:IPR000768("NAD:arginine ADP-ribosyltransferase, ART")|reactome:R-HSA-163125|go:"GO:0018120"(peptidyl-arginine ADP-ribosylation) - - - figure legend:Supp Table S4 and Supp Fig. S3|comment:"Coimmunoprecipitation with 34ED229 (T2) anti-TEX101 antibody"|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-testis)|taxid:9606(Homo sapiens) - 2020/03/24 2020/06/18 rogid:ZE4tXTFi7lUCcIbCL4KHzY3a6xM9606 rogid:JxQqlEa6lC6ZXSyTp7aaYCNxq189606 rigid:2wTqH12DHkSLcixvnxiJPZhqAc0 false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9BY14 uniprotkb:P20674 intact:EBI-12549378|ensembl:ENSP00000472769|uniprotkb:Q7L5R2|uniprotkb:Q9BPY7 intact:EBI-715032|uniprotkb:P30045|intact:EBI-1043629|uniprotkb:Q8TB65|ensembl:ENSP00000317780|ensembl:ENSP00000456386 psi-mi:tx101_human(display_long)|uniprotkb:TEX101(gene name)|psi-mi:TEX101(display_short)|uniprotkb:Cell surface receptor NYD-SP8(gene name synonym)|uniprotkb:SGRG(gene name synonym)|uniprotkb:Scleroderma-associated autoantigen(gene name synonym)|uniprotkb:Spermatogenesis-related gene protein(gene name synonym)|uniprotkb:UNQ867/PRO1884(orf name) psi-mi:cox5a_human(display_long)|uniprotkb:Cytochrome c oxidase polypeptide Va(gene name synonym)|uniprotkb:COX5A(gene name)|psi-mi:COX5A(display_short) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Schiza et al. (2018) imex:IM-28077|pubmed:30097533 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-25504841|imex:IM-28077-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000131126(gene)|ensembl:ENST00000598265(transcript)|go:"GO:0001669"(acrosomal vesicle)|go:"GO:0002080"(acrosomal membrane)|go:"GO:0005576"(extracellular region)|go:"GO:0005886"(plasma membrane)|go:"GO:0007339"(binding of sperm to zona pellucida)|go:"GO:0009566"(fertilization)|go:"GO:0030317"(flagellated sperm motility)|go:"GO:0044853"(plasma membrane raft)|go:"GO:0046658"(anchored component of plasma membrane)|go:"GO:1901317"(regulation of flagellated sperm motility)|interpro:IPR016054(Ly-6 antigen / uPA receptor -like)|rcsb pdb:7BPR|reactome:R-HSA-163125|refseq:NP_001123483.1|refseq:NP_113639.4 refseq:NP_004246.2|interpro:IPR003204(Cytochrome c oxidase, subunit Va)|interpro:IPR036545|mint:P20674|rcsb pdb:5Z62|reactome:R-HSA-5628897|reactome:R-HSA-611105|reactome:R-HSA-9707564|go:"GO:0046872"(metal ion binding)|ensembl:ENSG00000178741(gene)|ensembl:ENST00000322347(transcript)|ensembl:ENST00000564811(transcript)|go:"GO:0004129"(cytochrome-c oxidase activity)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005751"(mitochondrial respiratory chain complex IV)|go:"GO:0006123"(mitochondrial electron transport, cytochrome c to oxygen)|go:"GO:0009055"(electron transfer activity) - - - figure legend:Supp Table S4 and Supp Fig. S3|comment:"Coimmunoprecipitation with 34ED229 (T2) anti-TEX101 antibody"|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-testis)|taxid:9606(Homo sapiens) - 2020/03/24 2020/06/18 rogid:ZE4tXTFi7lUCcIbCL4KHzY3a6xM9606 rogid:dWvZKYawyJQwN29Mhkm44DXXqhg9606 rigid:2wTqH12DHkSLcixvnxiJPZhqAc0 false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9BY14 uniprotkb:O43242 intact:EBI-12549378|ensembl:ENSP00000472769|uniprotkb:Q7L5R2|uniprotkb:Q9BPY7 intact:EBI-357622|uniprotkb:Q96EI2|uniprotkb:Q9BQA4|ensembl:ENSP00000264639|uniprotkb:B4DT72|uniprotkb:B3KMW9 psi-mi:tx101_human(display_long)|uniprotkb:TEX101(gene name)|psi-mi:TEX101(display_short)|uniprotkb:Cell surface receptor NYD-SP8(gene name synonym)|uniprotkb:SGRG(gene name synonym)|uniprotkb:Scleroderma-associated autoantigen(gene name synonym)|uniprotkb:Spermatogenesis-related gene protein(gene name synonym)|uniprotkb:UNQ867/PRO1884(orf name) psi-mi:psmd3_human(display_long)|uniprotkb:PSMD3(gene name)|psi-mi:PSMD3(display_short)|uniprotkb:Proteasome subunit p58(gene name synonym)|uniprotkb:26S proteasome regulatory subunit S3(gene name synonym)|uniprotkb:26S proteasome regulatory subunit RPN3(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Schiza et al. (2018) imex:IM-28077|pubmed:30097533 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-25504841|imex:IM-28077-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000131126(gene)|ensembl:ENST00000598265(transcript)|go:"GO:0001669"(acrosomal vesicle)|go:"GO:0002080"(acrosomal membrane)|go:"GO:0005576"(extracellular region)|go:"GO:0005886"(plasma membrane)|go:"GO:0007339"(binding of sperm to zona pellucida)|go:"GO:0009566"(fertilization)|go:"GO:0030317"(flagellated sperm motility)|go:"GO:0044853"(plasma membrane raft)|go:"GO:0046658"(anchored component of plasma membrane)|go:"GO:1901317"(regulation of flagellated sperm motility)|interpro:IPR016054(Ly-6 antigen / uPA receptor -like)|rcsb pdb:7BPR|reactome:R-HSA-163125|refseq:NP_001123483.1|refseq:NP_113639.4 ensembl:ENSG00000108344(gene)|ensembl:ENST00000264639(transcript)|go:"GO:0000502"(proteasome complex)|go:"GO:0005576"(extracellular region)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0008541"(proteasome regulatory particle, lid subcomplex)|go:"GO:0016020"(membrane)|go:"GO:0022624"(proteasome accessory complex)|go:"GO:0030234"(enzyme regulator activity)|go:"GO:0034774"(secretory granule lumen)|go:"GO:0042176"(regulation of protein catabolic process)|go:"GO:0070062"(extracellular exosome)|go:"GO:1904813"(ficolin-1-rich granule lumen)|interpro:IPR000717(Proteasome component region PCI)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR013586(26S proteasome regulatory subunit, C-terminal)|interpro:IPR035267|interpro:IPR036390|mint:O43242|rcsb pdb:5GJQ|rcsb pdb:5GJR|rcsb pdb:5L4K|rcsb pdb:5LN3|rcsb pdb:5M32|rcsb pdb:5T0C|rcsb pdb:5T0G|rcsb pdb:5T0H|rcsb pdb:5T0I|rcsb pdb:5T0J|rcsb pdb:5VFP|rcsb pdb:5VFQ|rcsb pdb:5VFR|rcsb pdb:5VFS|rcsb pdb:5VFT|rcsb pdb:5VFU|rcsb pdb:5VGZ|rcsb pdb:5VHF|reactome:R-HSA-174113|reactome:R-HSA-174154|rcsb pdb:5VHH|rcsb pdb:5VHI|reactome:R-HSA-174178|rcsb pdb:5VHS|reactome:R-HSA-174184|rcsb pdb:6MSB|rcsb pdb:6MSD|rcsb pdb:6MSE|rcsb pdb:6MSG|rcsb pdb:6MSH|reactome:R-HSA-180534|rcsb pdb:6MSJ|reactome:R-HSA-180585|reactome:R-HSA-187577|rcsb pdb:6MSK|reactome:R-HSA-195253|reactome:R-HSA-202424|rcsb pdb:6WJD|reactome:R-HSA-211733|rcsb pdb:6WJN|reactome:R-HSA-1169091|reactome:R-HSA-1234176|reactome:R-HSA-2467813|reactome:R-HSA-2871837|reactome:R-HSA-1236974|reactome:R-HSA-1236978|reactome:R-HSA-349425|reactome:R-HSA-350562|reactome:R-HSA-174084|reactome:R-HSA-382556|reactome:R-HSA-450408|reactome:R-HSA-4608870|reactome:R-HSA-4641257|reactome:R-HSA-4641258|reactome:R-HSA-5358346|reactome:R-HSA-5362768|reactome:R-HSA-5607764|reactome:R-HSA-5610780|reactome:R-HSA-5610783|reactome:R-HSA-5610785|reactome:R-HSA-5632684|reactome:R-HSA-5658442|reactome:R-HSA-5668541|reactome:R-HSA-5676590|reactome:R-HSA-5678895|reactome:R-HSA-5687128|reactome:R-HSA-5607761|reactome:R-HSA-5689603|reactome:R-HSA-5689880|reactome:R-HSA-6798695|reactome:R-HSA-68827|reactome:R-HSA-68949|reactome:R-HSA-69017|reactome:R-HSA-69481|reactome:R-HSA-69601|reactome:R-HSA-75815|reactome:R-HSA-8852276|reactome:R-HSA-8932339|reactome:R-HSA-8939236|reactome:R-HSA-8939902|reactome:R-HSA-8941858|reactome:R-HSA-8948751|reactome:R-HSA-8951664|reactome:R-HSA-9010553|reactome:R-HSA-9020702|reactome:R-HSA-9604323|reactome:R-HSA-983168|reactome:R-HSA-8854050|refseq:NP_002800.2|dip:DIP-27571N - - - figure legend:Supp Table S4 and Supp Fig. S3|comment:"Coimmunoprecipitation with 34ED229 (T2) anti-TEX101 antibody"|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-testis)|taxid:9606(Homo sapiens) - 2020/03/24 2020/06/18 rogid:ZE4tXTFi7lUCcIbCL4KHzY3a6xM9606 rogid:C6CStW89nIAA3mzubyv5wfBwPHk9606 rigid:2wTqH12DHkSLcixvnxiJPZhqAc0 false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9BY14 uniprotkb:P61019 intact:EBI-12549378|ensembl:ENSP00000472769|uniprotkb:Q7L5R2|uniprotkb:Q9BPY7 intact:EBI-752037|uniprotkb:P08886|uniprotkb:B2R5W8|uniprotkb:B4DMQ5|ensembl:ENSP00000262646 psi-mi:tx101_human(display_long)|uniprotkb:TEX101(gene name)|psi-mi:TEX101(display_short)|uniprotkb:Cell surface receptor NYD-SP8(gene name synonym)|uniprotkb:SGRG(gene name synonym)|uniprotkb:Scleroderma-associated autoantigen(gene name synonym)|uniprotkb:Spermatogenesis-related gene protein(gene name synonym)|uniprotkb:UNQ867/PRO1884(orf name) psi-mi:rab2a_human(display_long)|uniprotkb:RAB2A(gene name)|psi-mi:RAB2A(display_short)|uniprotkb:RAB2(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Schiza et al. (2018) imex:IM-28077|pubmed:30097533 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-25504841|imex:IM-28077-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000131126(gene)|ensembl:ENST00000598265(transcript)|go:"GO:0001669"(acrosomal vesicle)|go:"GO:0002080"(acrosomal membrane)|go:"GO:0005576"(extracellular region)|go:"GO:0005886"(plasma membrane)|go:"GO:0007339"(binding of sperm to zona pellucida)|go:"GO:0009566"(fertilization)|go:"GO:0030317"(flagellated sperm motility)|go:"GO:0044853"(plasma membrane raft)|go:"GO:0046658"(anchored component of plasma membrane)|go:"GO:1901317"(regulation of flagellated sperm motility)|interpro:IPR016054(Ly-6 antigen / uPA receptor -like)|rcsb pdb:7BPR|reactome:R-HSA-163125|refseq:NP_001123483.1|refseq:NP_113639.4 refseq:NP_002856.1|refseq:NP_001229573.1|dip:DIP-316N|ensembl:ENSG00000104388(gene)|ensembl:ENST00000262646(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0007030"(Golgi organization)|go:"GO:0015031"(protein transport)|go:"GO:0019003"(GDP binding)|go:"GO:0033116"(endoplasmic reticulum-Golgi intermediate compartment membrane)|go:"GO:0042470"(melanosome)|go:"GO:0070062"(extracellular exosome)|interpro:IPR001806(Ras GTPase)|interpro:IPR005225(Small GTP-binding protein)|interpro:IPR027417|rcsb pdb:1Z0A|reactome:R-HSA-162658|reactome:R-HSA-8873719 - - - figure legend:Supp Table S4 and Supp Fig. S3|comment:"Coimmunoprecipitation with 34ED229 (T2) anti-TEX101 antibody"|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-testis)|taxid:9606(Homo sapiens) - 2020/03/24 2020/06/18 rogid:ZE4tXTFi7lUCcIbCL4KHzY3a6xM9606 rogid:MyG011KOkAtsvE2hU/fs21CEe/M9606 rigid:2wTqH12DHkSLcixvnxiJPZhqAc0 false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9BY14 uniprotkb:P04216 intact:EBI-12549378|ensembl:ENSP00000472769|uniprotkb:Q7L5R2|uniprotkb:Q9BPY7 intact:EBI-9071715|ensembl:ENSP00000284240|ensembl:ENSP00000431301|uniprotkb:Q9NSP1|uniprotkb:Q16008 psi-mi:tx101_human(display_long)|uniprotkb:TEX101(gene name)|psi-mi:TEX101(display_short)|uniprotkb:Cell surface receptor NYD-SP8(gene name synonym)|uniprotkb:SGRG(gene name synonym)|uniprotkb:Scleroderma-associated autoantigen(gene name synonym)|uniprotkb:Spermatogenesis-related gene protein(gene name synonym)|uniprotkb:UNQ867/PRO1884(orf name) psi-mi:thy1_human(display_long)|uniprotkb:CDw90(gene name synonym)|uniprotkb:Thy-1 antigen(gene name synonym)|uniprotkb:THY1(gene name)|psi-mi:THY1(display_short) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Schiza et al. (2018) imex:IM-28077|pubmed:30097533 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-25504841|imex:IM-28077-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000131126(gene)|ensembl:ENST00000598265(transcript)|go:"GO:0001669"(acrosomal vesicle)|go:"GO:0002080"(acrosomal membrane)|go:"GO:0005576"(extracellular region)|go:"GO:0005886"(plasma membrane)|go:"GO:0007339"(binding of sperm to zona pellucida)|go:"GO:0009566"(fertilization)|go:"GO:0030317"(flagellated sperm motility)|go:"GO:0044853"(plasma membrane raft)|go:"GO:0046658"(anchored component of plasma membrane)|go:"GO:1901317"(regulation of flagellated sperm motility)|interpro:IPR016054(Ly-6 antigen / uPA receptor -like)|rcsb pdb:7BPR|reactome:R-HSA-163125|refseq:NP_001123483.1|refseq:NP_113639.4 refseq:NP_006279.2|refseq:NP_001298089.1|refseq:NP_001298091.1|ensembl:ENSG00000154096(gene)|ensembl:ENST00000284240(transcript)|ensembl:ENST00000528522(transcript)|go:"GO:0001525"(angiogenesis)|go:"GO:0001952"(regulation of cell-matrix adhesion)|go:"GO:0002693"(positive regulation of cellular extravasation)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005178"(integrin binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0005925"(focal adhesion)|go:"GO:0006469"(negative regulation of protein kinase activity)|go:"GO:0007010"(cytoskeleton organization)|go:"GO:0007229"(integrin-mediated signaling pathway)|go:"GO:0007267"(cell-cell signaling)|go:"GO:0009897"(external side of plasma membrane)|go:"GO:0009986"(cell surface)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030336"(negative regulation of cell migration)|go:"GO:0030425"(dendrite)|go:"GO:0030426"(growth cone)|go:"GO:0030673"(axolemma)|go:"GO:0031362"(anchored component of external side of plasma membrane)|go:"GO:0032590"(dendrite membrane)|go:"GO:0032809"(neuronal cell body membrane)|go:"GO:0034116"(positive regulation of heterotypic cell-cell adhesion)|go:"GO:0034235"(GPI anchor binding)|go:"GO:0043113"(receptor clustering)|go:"GO:0043547"(positive regulation of GTPase activity)|go:"GO:0045121"(membrane raft)|go:"GO:0046549"(retinal cone cell development)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0048041"(focal adhesion assembly)|go:"GO:0050771"(negative regulation of axonogenesis)|go:"GO:0050852"(T cell receptor signaling pathway)|go:"GO:0050860"(negative regulation of T cell receptor signaling pathway)|go:"GO:0050870"(positive regulation of T cell activation)|go:"GO:0051281"(positive regulation of release of sequestered calcium ion into cytosol)|go:"GO:0051894"(positive regulation of focal adhesion assembly)|go:"GO:0061099"(negative regulation of protein tyrosine kinase activity)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070571"(negative regulation of neuron projection regeneration)|go:"GO:0098609"(cell-cell adhesion)|go:"GO:2000298"(regulation of Rho-dependent protein serine/threonine kinase activity)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR013106(Immunoglobulin V-set)|interpro:IPR013151(Immunoglobulin)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR033292|interpro:IPR036179|mint:P04216|reactome:R-HSA-163125 - - - figure legend:Supp Table S4 and Supp Fig. S3|comment:"Coimmunoprecipitation with 34ED229 (T2) anti-TEX101 antibody"|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-testis)|taxid:9606(Homo sapiens) - 2020/03/24 2020/06/18 rogid:ZE4tXTFi7lUCcIbCL4KHzY3a6xM9606 rogid:oJQb/vrYoN49IHy3OI4SmCXYtJY9606 rigid:2wTqH12DHkSLcixvnxiJPZhqAc0 false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9BY14 uniprotkb:O43390 intact:EBI-12549378|ensembl:ENSP00000472769|uniprotkb:Q7L5R2|uniprotkb:Q9BPY7 intact:EBI-713419|uniprotkb:S4R3J4|uniprotkb:Q5TEH1|ensembl:ENSP00000304405|ensembl:ENSP00000363741|ensembl:ENSP00000489252|ensembl:ENSP00000489371|uniprotkb:Q9BV64|uniprotkb:Q2L7G6 psi-mi:tx101_human(display_long)|uniprotkb:TEX101(gene name)|psi-mi:TEX101(display_short)|uniprotkb:Cell surface receptor NYD-SP8(gene name synonym)|uniprotkb:SGRG(gene name synonym)|uniprotkb:Scleroderma-associated autoantigen(gene name synonym)|uniprotkb:Spermatogenesis-related gene protein(gene name synonym)|uniprotkb:UNQ867/PRO1884(orf name) psi-mi:hnrpr_human(display_long)|uniprotkb:HNRPR(gene name synonym)|uniprotkb:HNRNPR(gene name)|psi-mi:HNRNPR(display_short) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Schiza et al. (2018) imex:IM-28077|pubmed:30097533 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-25504841|imex:IM-28077-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000131126(gene)|ensembl:ENST00000598265(transcript)|go:"GO:0001669"(acrosomal vesicle)|go:"GO:0002080"(acrosomal membrane)|go:"GO:0005576"(extracellular region)|go:"GO:0005886"(plasma membrane)|go:"GO:0007339"(binding of sperm to zona pellucida)|go:"GO:0009566"(fertilization)|go:"GO:0030317"(flagellated sperm motility)|go:"GO:0044853"(plasma membrane raft)|go:"GO:0046658"(anchored component of plasma membrane)|go:"GO:1901317"(regulation of flagellated sperm motility)|interpro:IPR016054(Ly-6 antigen / uPA receptor -like)|rcsb pdb:7BPR|reactome:R-HSA-163125|refseq:NP_001123483.1|refseq:NP_113639.4 refseq:NP_001095868.1|refseq:XP_005245768.1|ensembl:ENSG00000125944(gene)|ensembl:ENSG00000282958(gene)|ensembl:ENST00000302271(transcript)|ensembl:ENST00000374612(transcript)|ensembl:ENST00000634263(transcript)|ensembl:ENST00000634766(transcript)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0003730"(mRNA 3'-UTR binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005681"(spliceosomal complex)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0006397"(mRNA processing)|go:"GO:0007623"(circadian rhythm)|go:"GO:0030425"(dendrite)|go:"GO:0030426"(growth cone)|go:"GO:0043086"(negative regulation of catalytic activity)|go:"GO:0043679"(axon terminus)|go:"GO:0061157"(mRNA destabilization)|go:"GO:0071013"(catalytic step 2 spliceosome)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR006535(HnRNP R and Q splicing factor)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR034411|interpro:IPR035979|mint:O43390|rcsb pdb:2DK2|reactome:R-HSA-72163|reactome:R-HSA-72203|interpro:IPR041337|refseq:NP_005817.1|refseq:XP_011538773.1|refseq:NP_001284549.1|refseq:XP_016855497.1 - - - figure legend:Supp Table S4 and Supp Fig. S3|comment:"Coimmunoprecipitation with 34ED229 (T2) anti-TEX101 antibody"|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-testis)|taxid:9606(Homo sapiens) - 2020/03/24 2020/06/18 rogid:ZE4tXTFi7lUCcIbCL4KHzY3a6xM9606 rogid:UiOaRbnMd1S2FthR4RWltyq6xT49606 rigid:2wTqH12DHkSLcixvnxiJPZhqAc0 false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9BY14 uniprotkb:Q8IWT3 intact:EBI-12549378|ensembl:ENSP00000472769|uniprotkb:Q7L5R2|uniprotkb:Q9BPY7 intact:EBI-311123|uniprotkb:O75188|uniprotkb:Q68CP2|uniprotkb:Q68D92|uniprotkb:Q8N3W9|uniprotkb:Q9BU56|intact:EBI-2845754|uniprotkb:Q5TCY3|ensembl:ENSP00000252050 psi-mi:tx101_human(display_long)|uniprotkb:TEX101(gene name)|psi-mi:TEX101(display_short)|uniprotkb:Cell surface receptor NYD-SP8(gene name synonym)|uniprotkb:SGRG(gene name synonym)|uniprotkb:Scleroderma-associated autoantigen(gene name synonym)|uniprotkb:Spermatogenesis-related gene protein(gene name synonym)|uniprotkb:UNQ867/PRO1884(orf name) psi-mi:cul9_human(display_long)|uniprotkb:CUL9(gene name)|psi-mi:CUL9(display_short)|uniprotkb:H7AP1(gene name synonym)|uniprotkb:KIAA0708(gene name synonym)|uniprotkb:UbcH7-associated protein 1(gene name synonym)|uniprotkb:PARC(gene name synonym)|uniprotkb:p53-associated parkin-like cytoplasmic protein(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Schiza et al. (2018) imex:IM-28077|pubmed:30097533 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-25504841|imex:IM-28077-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000131126(gene)|ensembl:ENST00000598265(transcript)|go:"GO:0001669"(acrosomal vesicle)|go:"GO:0002080"(acrosomal membrane)|go:"GO:0005576"(extracellular region)|go:"GO:0005886"(plasma membrane)|go:"GO:0007339"(binding of sperm to zona pellucida)|go:"GO:0009566"(fertilization)|go:"GO:0030317"(flagellated sperm motility)|go:"GO:0044853"(plasma membrane raft)|go:"GO:0046658"(anchored component of plasma membrane)|go:"GO:1901317"(regulation of flagellated sperm motility)|interpro:IPR016054(Ly-6 antigen / uPA receptor -like)|rcsb pdb:7BPR|reactome:R-HSA-163125|refseq:NP_001123483.1|refseq:NP_113639.4 refseq:NP_055904.1|ensembl:ENSG00000112659(gene)|ensembl:ENST00000252050(transcript)|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0005524"(ATP binding)|go:"GO:0005829"(cytosol)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0007088"(regulation of mitotic nuclear division)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0016740"(transferase activity)|go:"GO:0031461"(cullin-RING ubiquitin ligase complex)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0046872"(metal ion binding)|interpro:IPR001373(Cullin, N-terminal region)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR002867(Zinc finger, C6HC-type)|interpro:IPR004939(Anaphase-promoting complex, subunit 10)|interpro:IPR008979(Galactose-binding like)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR014722(Translation protein SH3-like, subgroup)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR016157(Cullin, conserved site)|interpro:IPR016158(Cullin homology)|interpro:IPR017907|interpro:IPR019559|interpro:IPR021097|interpro:IPR031222|interpro:IPR036317|interpro:IPR036388|interpro:IPR044066|mint:Q8IWT3|rcsb pdb:2JUF|reactome:R-HSA-8951664 - - - figure legend:Supp Table S4 and Supp Fig. S3|comment:"Coimmunoprecipitation with 34ED229 (T2) anti-TEX101 antibody"|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-testis)|taxid:9606(Homo sapiens) - 2020/03/24 2020/06/18 rogid:ZE4tXTFi7lUCcIbCL4KHzY3a6xM9606 rogid:l3eOdyfEVm0PkkDykJXN270o1Kc9606 rigid:2wTqH12DHkSLcixvnxiJPZhqAc0 false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9BY14 uniprotkb:Q9P2N5 intact:EBI-12549378|ensembl:ENSP00000472769|uniprotkb:Q7L5R2|uniprotkb:Q9BPY7 intact:EBI-2801823|uniprotkb:Q8IYW9|ensembl:ENSP00000265271 psi-mi:tx101_human(display_long)|uniprotkb:TEX101(gene name)|psi-mi:TEX101(display_short)|uniprotkb:Cell surface receptor NYD-SP8(gene name synonym)|uniprotkb:SGRG(gene name synonym)|uniprotkb:Scleroderma-associated autoantigen(gene name synonym)|uniprotkb:Spermatogenesis-related gene protein(gene name synonym)|uniprotkb:UNQ867/PRO1884(orf name) psi-mi:rbm27_human(display_long)|uniprotkb:KIAA1311(gene name synonym)|uniprotkb:RNA-binding motif protein 27(gene name synonym)|uniprotkb:RBM27(gene name)|psi-mi:RBM27(display_short) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Schiza et al. (2018) imex:IM-28077|pubmed:30097533 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-25504841|imex:IM-28077-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000131126(gene)|ensembl:ENST00000598265(transcript)|go:"GO:0001669"(acrosomal vesicle)|go:"GO:0002080"(acrosomal membrane)|go:"GO:0005576"(extracellular region)|go:"GO:0005886"(plasma membrane)|go:"GO:0007339"(binding of sperm to zona pellucida)|go:"GO:0009566"(fertilization)|go:"GO:0030317"(flagellated sperm motility)|go:"GO:0044853"(plasma membrane raft)|go:"GO:0046658"(anchored component of plasma membrane)|go:"GO:1901317"(regulation of flagellated sperm motility)|interpro:IPR016054(Ly-6 antigen / uPA receptor -like)|rcsb pdb:7BPR|reactome:R-HSA-163125|refseq:NP_001123483.1|refseq:NP_113639.4 refseq:NP_061862.1|ensembl:ENSG00000091009(gene)|ensembl:ENST00000265271(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006397"(mRNA processing)|go:"GO:0016607"(nuclear speck)|go:"GO:0046872"(metal ion binding)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR000571(Zinc finger, CCCH-type)|interpro:IPR002483(Splicing factor PWI)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR034451|interpro:IPR035979 - - - figure legend:Supp Table S4 and Supp Fig. S3|comment:"Coimmunoprecipitation with 34ED229 (T2) anti-TEX101 antibody"|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-testis)|taxid:9606(Homo sapiens) - 2020/03/24 2020/06/18 rogid:ZE4tXTFi7lUCcIbCL4KHzY3a6xM9606 rogid:TOeh1JAElLGeLfz+YkgWIsS4V0k9606 rigid:2wTqH12DHkSLcixvnxiJPZhqAc0 false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9BY14 uniprotkb:Q7Z6Z7 intact:EBI-12549378|ensembl:ENSP00000472769|uniprotkb:Q7L5R2|uniprotkb:Q9BPY7 intact:EBI-625934|uniprotkb:O15029|uniprotkb:Q4G2Z2|uniprotkb:Q5H961|uniprotkb:Q6P4D0|uniprotkb:Q8NG67|uniprotkb:Q9BUI0|uniprotkb:Q9HCJ4|uniprotkb:Q9NSL6|uniprotkb:Q9P0A9|ensembl:ENSP00000262854|ensembl:ENSP00000340648 psi-mi:tx101_human(display_long)|uniprotkb:TEX101(gene name)|psi-mi:TEX101(display_short)|uniprotkb:Cell surface receptor NYD-SP8(gene name synonym)|uniprotkb:SGRG(gene name synonym)|uniprotkb:Scleroderma-associated autoantigen(gene name synonym)|uniprotkb:Spermatogenesis-related gene protein(gene name synonym)|uniprotkb:UNQ867/PRO1884(orf name) psi-mi:huwe1_human(display_long)|uniprotkb:HECT, UBA and WWE domain-containing protein 1(gene name synonym)|uniprotkb:Upstream regulatory element-binding protein 1(gene name synonym)|uniprotkb:Mcl-1 ubiquitin ligase E3(gene name synonym)|uniprotkb:ARF-binding protein 1(gene name synonym)|uniprotkb:Large structure of UREB1(gene name synonym)|uniprotkb:Homologous to E6AP carboxyl terminus homologous protein 9(gene name synonym)|uniprotkb:HUWE1(gene name)|psi-mi:HUWE1(display_short)|uniprotkb:KIAA0312(gene name synonym)|uniprotkb:KIAA1578(gene name synonym)|uniprotkb:HSPC272(orf name)|uniprotkb:HECT-type E3 ubiquitin transferase HUWE1(gene name synonym)|uniprotkb:UREB1(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Schiza et al. (2018) imex:IM-28077|pubmed:30097533 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-25505061|imex:IM-28077-3 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000131126(gene)|ensembl:ENST00000598265(transcript)|go:"GO:0001669"(acrosomal vesicle)|go:"GO:0002080"(acrosomal membrane)|go:"GO:0005576"(extracellular region)|go:"GO:0005886"(plasma membrane)|go:"GO:0007339"(binding of sperm to zona pellucida)|go:"GO:0009566"(fertilization)|go:"GO:0030317"(flagellated sperm motility)|go:"GO:0044853"(plasma membrane raft)|go:"GO:0046658"(anchored component of plasma membrane)|go:"GO:1901317"(regulation of flagellated sperm motility)|interpro:IPR016054(Ly-6 antigen / uPA receptor -like)|rcsb pdb:7BPR|reactome:R-HSA-163125|refseq:NP_001123483.1|refseq:NP_113639.4 ensembl:ENSG00000086758(gene)|ensembl:ENST00000262854(transcript)|ensembl:ENST00000342160(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0003677"(DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005576"(extracellular region)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006284"(base-excision repair)|go:"GO:0006513"(protein monoubiquitination)|go:"GO:0007030"(Golgi organization)|go:"GO:0010637"(negative regulation of mitochondrial fusion)|go:"GO:0016020"(membrane)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0016574"(histone ubiquitination)|go:"GO:0030154"(cell differentiation)|go:"GO:0031398"(positive regulation of protein ubiquitination)|go:"GO:0032922"(circadian regulation of gene expression)|go:"GO:0034774"(secretory granule lumen)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0045732"(positive regulation of protein catabolic process)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0070062"(extracellular exosome)|go:"GO:0098779"(positive regulation of mitophagy in response to mitochondrial depolarization)|go:"GO:1903955"(positive regulation of protein targeting to mitochondrion)|go:"GO:1904813"(ficolin-1-rich granule lumen)|interpro:IPR000569(HECT)|interpro:IPR004170(WWE)|interpro:IPR009060(UBA-like)|interpro:IPR010309(E3 ubiquitin ligase, region of unknown function DUF908)|interpro:IPR010314(E3 ubiquitin ligase, region of unknown function DUF913)|interpro:IPR015940(Ubiquitin-associated/translation elongation factor EF1B, N-terminal, eukaryote)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR025527|interpro:IPR035983|interpro:IPR037197|interpro:IPR041918|mint:Q7Z6Z7|rcsb pdb:2EKK|rcsb pdb:2MUL|rcsb pdb:3G1N|go:"GO:0061025"(membrane fusion)|rcsb pdb:5C6H|rcsb pdb:5LP8|rcsb pdb:6FYH|rcsb pdb:6MIW|rcsb pdb:6PFL|reactome:R-HSA-6798695|rcsb pdb:3H1D|reactome:R-HSA-983168|refseq:NP_113584.3|refseq:XP_005262022.1|dip:DIP-34362N - - - figure legend:Fig.2A,Supp Table S5|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-testis)|taxid:9606(Homo sapiens) - 2020/03/24 2021/11/30 rogid:ZE4tXTFi7lUCcIbCL4KHzY3a6xM9606 rogid:TnIn0mcFc81bJlMkyWTtq3n/uOg9606 rigid:/AFat0DrynAJ5ofEnoPSTThlxCE false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9BY14 uniprotkb:P54868 intact:EBI-12549378|ensembl:ENSP00000472769|uniprotkb:Q7L5R2|uniprotkb:Q9BPY7 intact:EBI-8063984|intact:UNK-5380486|uniprotkb:D3Y5K6|uniprotkb:Q5SZU2|uniprotkb:Q6IBF4|intact:UNK-5451690|uniprotkb:B7Z8R3|ensembl:ENSP00000358414 psi-mi:tx101_human(display_long)|uniprotkb:TEX101(gene name)|psi-mi:TEX101(display_short)|uniprotkb:Cell surface receptor NYD-SP8(gene name synonym)|uniprotkb:SGRG(gene name synonym)|uniprotkb:Scleroderma-associated autoantigen(gene name synonym)|uniprotkb:Spermatogenesis-related gene protein(gene name synonym)|uniprotkb:UNQ867/PRO1884(orf name) psi-mi:hmcs2_human(display_long)|uniprotkb:HMGCS2(gene name)|psi-mi:HMGCS2(display_short)|uniprotkb:3-hydroxy-3-methylglutaryl coenzyme A synthase(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Schiza et al. (2018) imex:IM-28077|pubmed:30097533 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-25505061|imex:IM-28077-3 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000131126(gene)|ensembl:ENST00000598265(transcript)|go:"GO:0001669"(acrosomal vesicle)|go:"GO:0002080"(acrosomal membrane)|go:"GO:0005576"(extracellular region)|go:"GO:0005886"(plasma membrane)|go:"GO:0007339"(binding of sperm to zona pellucida)|go:"GO:0009566"(fertilization)|go:"GO:0030317"(flagellated sperm motility)|go:"GO:0044853"(plasma membrane raft)|go:"GO:0046658"(anchored component of plasma membrane)|go:"GO:1901317"(regulation of flagellated sperm motility)|interpro:IPR016054(Ly-6 antigen / uPA receptor -like)|rcsb pdb:7BPR|reactome:R-HSA-163125|refseq:NP_001123483.1|refseq:NP_113639.4 refseq:XP_011539615.1|refseq:NP_001159579.1|refseq:NP_005509.1|ensembl:ENSG00000134240(gene)|ensembl:ENST00000369406(transcript)|go:"GO:0004421"(hydroxymethylglutaryl-CoA synthase activity)|go:"GO:0005739"(mitochondrion)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0006084"(acetyl-CoA metabolic process)|go:"GO:0006695"(cholesterol biosynthetic process)|go:"GO:0010142"(farnesyl diphosphate biosynthetic process, mevalonate pathway)|go:"GO:0042802"(identical protein binding)|go:"GO:0046951"(ketone body biosynthetic process)|interpro:IPR000590(Hydroxymethylglutaryl-coenzyme A synthase, active site)|interpro:IPR010122(Hydroxymethylglutaryl-CoA synthase, eukaryotic)|interpro:IPR013528(Hydroxymethylglutaryl-coenzyme A synthase, N-terminal)|interpro:IPR013746(Hydroxymethylglutaryl-coenzyme A synthase C-terminal)|interpro:IPR016039(Thiolase-like)|rcsb pdb:2WYA|reactome:R-HSA-1989781|reactome:R-HSA-77111 - - comment:mint|function:This enzyme condenses acetyl-CoA with acetoacetyl-CoA to form HMG-CoA, which is the substrate for HMG-CoA reductase|function:"Defects in HMGCS2 are the cause of HMG-CoA synthase deficiency [MIM:605911]; also known as deficiency of mitochondrial 3-hydroxy-3-methylglutaryl-CoA synthase 2. Affected individuals present with severe hypoketotic hypoglycemia, mild hepatomegaly, or fatty liver, and a nondiagnostic pattern of urinary organic acids with increase of medium and short chain dicarboxylic acids" figure legend:Fig.2A,Supp Table S5|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-testis)|taxid:9606(Homo sapiens) - 2020/03/24 2021/11/30 rogid:ZE4tXTFi7lUCcIbCL4KHzY3a6xM9606 rogid:YP6FzG8Z0RqhdLrFUFu5EyEJHoc9606 rigid:/AFat0DrynAJ5ofEnoPSTThlxCE false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9BY14 uniprotkb:Q9BYF1 intact:EBI-12549378|ensembl:ENSP00000472769|uniprotkb:Q7L5R2|uniprotkb:Q9BPY7 intact:EBI-7730807|ensembl:ENSP00000252519|ensembl:ENSP00000389326|ensembl:ENSP00000504103|ensembl:ENSP00000505992|intact:EBI-25767352|uniprotkb:Q9UFZ6|uniprotkb:Q9NRA7|intact:MINT-4538816|uniprotkb:C7ECU1|uniprotkb:Q6UWP0|uniprotkb:Q86WT0|uniprotkb:A0A7D6JAD5|intact:EBI-15814450 psi-mi:tx101_human(display_long)|uniprotkb:TEX101(gene name)|psi-mi:TEX101(display_short)|uniprotkb:Cell surface receptor NYD-SP8(gene name synonym)|uniprotkb:SGRG(gene name synonym)|uniprotkb:Scleroderma-associated autoantigen(gene name synonym)|uniprotkb:Spermatogenesis-related gene protein(gene name synonym)|uniprotkb:UNQ867/PRO1884(orf name) psi-mi:ace2_human(display_long)|uniprotkb:ACE2(gene name)|psi-mi:ACE2(display_short)|uniprotkb:UNQ868/PRO1885(orf name)|uniprotkb:Angiotensin-converting enzyme homolog(gene name synonym)|uniprotkb:Metalloprotease MPROT15(gene name synonym)|uniprotkb:Angiotensin-converting enzyme-related carboxypeptidase(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Schiza et al. (2018) imex:IM-28077|pubmed:30097533 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-25505061|imex:IM-28077-3 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000131126(gene)|ensembl:ENST00000598265(transcript)|go:"GO:0001669"(acrosomal vesicle)|go:"GO:0002080"(acrosomal membrane)|go:"GO:0005576"(extracellular region)|go:"GO:0005886"(plasma membrane)|go:"GO:0007339"(binding of sperm to zona pellucida)|go:"GO:0009566"(fertilization)|go:"GO:0030317"(flagellated sperm motility)|go:"GO:0044853"(plasma membrane raft)|go:"GO:0046658"(anchored component of plasma membrane)|go:"GO:1901317"(regulation of flagellated sperm motility)|interpro:IPR016054(Ly-6 antigen / uPA receptor -like)|rcsb pdb:7BPR|reactome:R-HSA-163125|refseq:NP_001123483.1|refseq:NP_113639.4 ensembl:ENST00000252519(transcript)|ensembl:ENST00000427411(transcript)|ensembl:ENST00000678073(transcript)|ensembl:ENST00000680121(transcript)|go:"GO:0001618"(virus receptor activity)|go:"GO:0001817"(regulation of cytokine production)|go:"GO:0002003"(angiotensin maturation)|go:"GO:0003051"(angiotensin-mediated drinking behavior)|go:"GO:0003081"(regulation of systemic arterial blood pressure by renin-angiotensin)|go:"GO:0004175"(endopeptidase activity)|go:"GO:0004180"(carboxypeptidase activity)|go:"GO:0004181"(metallocarboxypeptidase activity)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0005788"(endoplasmic reticulum lumen)|go:"GO:0005886"(plasma membrane)|go:"GO:0005929"(cilium)|go:"GO:0006508"(proteolysis)|go:"GO:0008237"(metallopeptidase activity)|go:"GO:0008241"(peptidyl-dipeptidase activity)|go:"GO:0008270"(zinc ion binding)|go:"GO:0009986"(cell surface)|go:"GO:0015827"(tryptophan transport)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0019229"(regulation of vasoconstriction)|go:"GO:0022898"(regulation of transmembrane transporter activity)|go:"GO:0030666"(endocytic vesicle membrane)|go:"GO:0031526"(brush border membrane)|go:"GO:0042127"(regulation of cell population proliferation)|go:"GO:0042802"(identical protein binding)|go:"GO:0045121"(membrane raft)|go:"GO:0046718"(viral entry into host cell)|go:"GO:0046813"(receptor-mediated virion attachment to host cell)|ensembl:ENSG00000130234(gene)|go:"GO:0051957"(positive regulation of amino acid transport)|go:"GO:0060452"(positive regulation of cardiac muscle contraction)|go:"GO:0070062"(extracellular exosome)|go:"GO:0097746"(blood vessel diameter maintenance)|go:"GO:1903598"(positive regulation of gap junction assembly)|go:"GO:1903779"(regulation of cardiac conduction)|go:"GO:1905737"(positive regulation of L-proline import across plasma membrane)|go:"GO:2000272"(negative regulation of signaling receptor activity)|go:"GO:2000379"(positive regulation of reactive oxygen species metabolic process)|interpro:IPR001548(Peptidase M2, peptidyl-dipeptidase A)|interpro:IPR031588|mint:Q9BYF1|rcsb pdb:1R42|rcsb pdb:1R4L|rcsb pdb:1XJP|rcsb pdb:2AJF|rcsb pdb:3D0G|rcsb pdb:3D0H|rcsb pdb:3D0I|rcsb pdb:3KBH|rcsb pdb:3SCI|rcsb pdb:3SCJ|rcsb pdb:3SCK|rcsb pdb:3SCL|rcsb pdb:6ACG|rcsb pdb:6ACJ|rcsb pdb:6ACK|rcsb pdb:6CS2|rcsb pdb:6LZG|rcsb pdb:6M0J|rcsb pdb:6M17|rcsb pdb:6M18|go:"GO:0050727"(regulation of inflammatory response)|rcsb pdb:6M1D|rcsb pdb:6VW1|rcsb pdb:7A91|rcsb pdb:7A92|rcsb pdb:7A94|rcsb pdb:7A95|rcsb pdb:7A96|rcsb pdb:7A97|rcsb pdb:7A98|rcsb pdb:7BH9|rcsb pdb:7CT5|rcsb pdb:7DDO|rcsb pdb:7DDP|rcsb pdb:7DF4|rcsb pdb:7DMU|rcsb pdb:7DWX|rcsb pdb:7DX4|rcsb pdb:7DX5|rcsb pdb:7DX6|rcsb pdb:7DX7|rcsb pdb:7DX8|rcsb pdb:7DX9|rcsb pdb:7JVO|rcsb pdb:7KJ2|rcsb pdb:7KJ3|rcsb pdb:7KJ4|rcsb pdb:7KMB|rcsb pdb:7KMS|rcsb pdb:7KMZ|rcsb pdb:7KNB|rcsb pdb:7KNE|rcsb pdb:7KNH|rcsb pdb:7L0N|rcsb pdb:7L7F|rcsb pdb:7LO4|rcsb pdb:7MJM|rcsb pdb:7MJN|rcsb pdb:7NXC|reactome:R-HSA-2022377|reactome:R-HSA-9678110|reactome:R-HSA-9679191|reactome:R-HSA-9694614|rcsb pdb:7KNI|dip:DIP-44689N|refseq:NP_068576.1 - - comment:mint|function:Carboxypeptidase which converts angiotensin I to angiotensin 1-9, a peptide of unknown function, and angiotensin II to angiotensin 1-7, a vasodilator. Also able to hydrolyze apelin-13 and dynorphin-13 with high efficiency. May be an important regulator of heart function. In case of human coronaviruses SARS and HCoV-NL63 infections, serve as functional receptor for the spike glycoprotein of both coronaviruses figure legend:Fig.2A,Supp Table S5|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-testis)|taxid:9606(Homo sapiens) - 2020/03/24 2021/11/30 rogid:ZE4tXTFi7lUCcIbCL4KHzY3a6xM9606 rogid:ZxuR6gzxz4Ns+hYH5uksGdn8S7o9606 rigid:/AFat0DrynAJ5ofEnoPSTThlxCE false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9BY14 uniprotkb:P00167 intact:EBI-12549378|ensembl:ENSP00000472769|uniprotkb:Q7L5R2|uniprotkb:Q9BPY7 intact:EBI-1047284|uniprotkb:A8MV91|uniprotkb:Q6IB14|uniprotkb:F8WEU4|ensembl:ENSP00000341625 psi-mi:tx101_human(display_long)|uniprotkb:TEX101(gene name)|psi-mi:TEX101(display_short)|uniprotkb:Cell surface receptor NYD-SP8(gene name synonym)|uniprotkb:SGRG(gene name synonym)|uniprotkb:Scleroderma-associated autoantigen(gene name synonym)|uniprotkb:Spermatogenesis-related gene protein(gene name synonym)|uniprotkb:UNQ867/PRO1884(orf name) psi-mi:cyb5_human(display_long)|uniprotkb:CYB5A(gene name)|psi-mi:CYB5A(display_short)|uniprotkb:CYB5(gene name synonym)|uniprotkb:Microsomal cytochrome b5 type A(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Schiza et al. (2018) imex:IM-28077|pubmed:30097533 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-25505061|imex:IM-28077-3 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000131126(gene)|ensembl:ENST00000598265(transcript)|go:"GO:0001669"(acrosomal vesicle)|go:"GO:0002080"(acrosomal membrane)|go:"GO:0005576"(extracellular region)|go:"GO:0005886"(plasma membrane)|go:"GO:0007339"(binding of sperm to zona pellucida)|go:"GO:0009566"(fertilization)|go:"GO:0030317"(flagellated sperm motility)|go:"GO:0044853"(plasma membrane raft)|go:"GO:0046658"(anchored component of plasma membrane)|go:"GO:1901317"(regulation of flagellated sperm motility)|interpro:IPR016054(Ly-6 antigen / uPA receptor -like)|rcsb pdb:7BPR|reactome:R-HSA-163125|refseq:NP_001123483.1|refseq:NP_113639.4 refseq:NP_001905.1|refseq:NP_683725.1|refseq:XP_011524137.1|refseq:NP_001177736.1|go:"GO:0005829"(cytosol)|go:"GO:0009055"(electron transfer activity)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0019899"(enzyme binding)|go:"GO:0020037"(heme binding)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0046686"(response to cadmium ion)|go:"GO:0046872"(metal ion binding)|interpro:IPR001199(Cytochrome b5)|interpro:IPR018506|interpro:IPR036400|rcsb pdb:2I96|reactome:R-HSA-196836|reactome:R-HSA-9609523|ensembl:ENSG00000166347(gene)|ensembl:ENST00000340533(transcript)|go:"GO:0004129"(cytochrome-c oxidase activity)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005789"(endoplasmic reticulum membrane) - - - figure legend:Fig.2A,Supp Table S5|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-testis)|taxid:9606(Homo sapiens) - 2020/03/24 2021/11/30 rogid:ZE4tXTFi7lUCcIbCL4KHzY3a6xM9606 rogid:nZ/xafhkGjHBGCIWhtvBD1mtVSQ9606 rigid:/AFat0DrynAJ5ofEnoPSTThlxCE false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9BY14 uniprotkb:O60664 intact:EBI-12549378|ensembl:ENSP00000472769|uniprotkb:Q7L5R2|uniprotkb:Q9BPY7 intact:EBI-725795|uniprotkb:Q53G77|uniprotkb:Q9BS03|uniprotkb:Q9UBD7|uniprotkb:Q9UP92|uniprotkb:A8K4Y9|intact:EBI-11103673|uniprotkb:K7EQF4|ensembl:ENSP00000221957 psi-mi:tx101_human(display_long)|uniprotkb:TEX101(gene name)|psi-mi:TEX101(display_short)|uniprotkb:Cell surface receptor NYD-SP8(gene name synonym)|uniprotkb:SGRG(gene name synonym)|uniprotkb:Scleroderma-associated autoantigen(gene name synonym)|uniprotkb:Spermatogenesis-related gene protein(gene name synonym)|uniprotkb:UNQ867/PRO1884(orf name) psi-mi:plin3_human(display_long)|uniprotkb:Cargo selection protein TIP47(gene name synonym)|uniprotkb:47 kDa mannose 6-phosphate receptor-binding protein(gene name synonym)|uniprotkb:Placental protein 17(gene name synonym)|uniprotkb:PLIN3(gene name)|psi-mi:PLIN3(display_short)|uniprotkb:TIP47(gene name synonym)|uniprotkb:M6PRBP1(gene name synonym)|uniprotkb:Mannose-6-phosphate receptor-binding protein 1(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Schiza et al. (2018) imex:IM-28077|pubmed:30097533 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-25505061|imex:IM-28077-3 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000131126(gene)|ensembl:ENST00000598265(transcript)|go:"GO:0001669"(acrosomal vesicle)|go:"GO:0002080"(acrosomal membrane)|go:"GO:0005576"(extracellular region)|go:"GO:0005886"(plasma membrane)|go:"GO:0007339"(binding of sperm to zona pellucida)|go:"GO:0009566"(fertilization)|go:"GO:0030317"(flagellated sperm motility)|go:"GO:0044853"(plasma membrane raft)|go:"GO:0046658"(anchored component of plasma membrane)|go:"GO:1901317"(regulation of flagellated sperm motility)|interpro:IPR016054(Ly-6 antigen / uPA receptor -like)|rcsb pdb:7BPR|reactome:R-HSA-163125|refseq:NP_001123483.1|refseq:NP_113639.4 refseq:NP_001157666.1|refseq:NP_001157661.1|refseq:NP_005808.3|go:"GO:0016020"(membrane)|go:"GO:0016192"(vesicle-mediated transport)|go:"GO:0019915"(lipid storage)|go:"GO:0030133"(transport vesicle)|ensembl:ENSG00000105355(gene)|go:"GO:0045296"(cadherin binding)|interpro:IPR004279(Perilipin)|reactome:R-HSA-163560|reactome:R-HSA-6811440|reactome:R-HSA-9613354|ensembl:ENST00000221957(transcript)|reactome:R-HSA-9613829|reactome:R-HSA-9615710|reactome:R-HSA-9706019|go:"GO:0005737"(cytoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005811"(lipid droplet)|go:"GO:0005829"(cytosol)|go:"GO:0010008"(endosome membrane)|go:"GO:0010890"(positive regulation of sequestering of triglyceride) - - - figure legend:Fig.2A,Supp Table S5|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-testis)|taxid:9606(Homo sapiens) - 2020/03/24 2021/11/30 rogid:ZE4tXTFi7lUCcIbCL4KHzY3a6xM9606 rogid:U+skqZ/oQtQscaEvfdh+AVnCCKA9606 rigid:/AFat0DrynAJ5ofEnoPSTThlxCE false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9BY14 uniprotkb:P02652 intact:EBI-12549378|ensembl:ENSP00000472769|uniprotkb:Q7L5R2|uniprotkb:Q9BPY7 intact:EBI-1171525|uniprotkb:B2R524|ensembl:ENSP00000356969 psi-mi:tx101_human(display_long)|uniprotkb:TEX101(gene name)|psi-mi:TEX101(display_short)|uniprotkb:Cell surface receptor NYD-SP8(gene name synonym)|uniprotkb:SGRG(gene name synonym)|uniprotkb:Scleroderma-associated autoantigen(gene name synonym)|uniprotkb:Spermatogenesis-related gene protein(gene name synonym)|uniprotkb:UNQ867/PRO1884(orf name) psi-mi:apoa2_human(display_long)|uniprotkb:APOA2(gene name)|psi-mi:APOA2(display_short)|uniprotkb:Apolipoprotein A2(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Schiza et al. (2018) imex:IM-28077|pubmed:30097533 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-25505061|imex:IM-28077-3 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000131126(gene)|ensembl:ENST00000598265(transcript)|go:"GO:0001669"(acrosomal vesicle)|go:"GO:0002080"(acrosomal membrane)|go:"GO:0005576"(extracellular region)|go:"GO:0005886"(plasma membrane)|go:"GO:0007339"(binding of sperm to zona pellucida)|go:"GO:0009566"(fertilization)|go:"GO:0030317"(flagellated sperm motility)|go:"GO:0044853"(plasma membrane raft)|go:"GO:0046658"(anchored component of plasma membrane)|go:"GO:1901317"(regulation of flagellated sperm motility)|interpro:IPR016054(Ly-6 antigen / uPA receptor -like)|rcsb pdb:7BPR|reactome:R-HSA-163125|refseq:NP_001123483.1|refseq:NP_113639.4 refseq:NP_001634.1|ensembl:ENSG00000158874(gene)|ensembl:ENST00000367990(transcript)|go:"GO:0002526"(acute inflammatory response)|go:"GO:0002719"(negative regulation of cytokine production involved in immune response)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0008289"(lipid binding)|go:"GO:0009395"(phospholipid catabolic process)|go:"GO:0009749"(response to glucose)|go:"GO:0010873"(positive regulation of cholesterol esterification)|go:"GO:0010903"(negative regulation of very-low-density lipoprotein particle remodeling)|go:"GO:0015485"(cholesterol binding)|go:"GO:0018158"(protein oxidation)|go:"GO:0005319"(lipid transporter activity)|go:"GO:0018206"(peptidyl-methionine modification)|go:"GO:0030300"(regulation of intestinal cholesterol absorption)|go:"GO:0030301"(cholesterol transport)|go:"GO:0031072"(heat shock protein binding)|go:"GO:0005543"(phospholipid binding)|go:"GO:0031100"(animal organ regeneration)|go:"GO:0031210"(phosphatidylcholine binding)|go:"GO:0031647"(regulation of protein stability)|go:"GO:0032375"(negative regulation of cholesterol transport)|go:"GO:0005576"(extracellular region)|go:"GO:0005769"(early endosome)|go:"GO:0005788"(endoplasmic reticulum lumen)|go:"GO:0032757"(positive regulation of interleukin-8 production)|go:"GO:0033344"(cholesterol efflux)|go:"GO:0033700"(phospholipid efflux)|go:"GO:0034190"(apolipoprotein receptor binding)|go:"GO:0034361"(very-low-density lipoprotein particle)|go:"GO:0034364"(high-density lipoprotein particle)|go:"GO:0005829"(cytosol)|go:"GO:0006641"(triglyceride metabolic process)|go:"GO:0006656"(phosphatidylcholine biosynthetic process)|go:"GO:0008035"(high-density lipoprotein particle binding)|go:"GO:0008203"(cholesterol metabolic process)|go:"GO:0034366"(spherical high-density lipoprotein particle)|go:"GO:0034370"(triglyceride-rich lipoprotein particle remodeling)|go:"GO:0034374"(low-density lipoprotein particle remodeling)|go:"GO:0034375"(high-density lipoprotein particle remodeling)|go:"GO:0034380"(high-density lipoprotein particle assembly)|go:"GO:0034384"(high-density lipoprotein particle clearance)|go:"GO:0042157"(lipoprotein metabolic process)|go:"GO:0042493"|go:"GO:0042627"(chylomicron)|go:"GO:0042632"(cholesterol homeostasis)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043627"(response to estrogen)|go:"GO:0043691"(reverse cholesterol transport)|go:"GO:0046340"(diacylglycerol catabolic process)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0050766"(positive regulation of phagocytosis)|go:"GO:0050821"(protein stabilization)|go:"GO:0050995"(negative regulation of lipid catabolic process)|go:"GO:0050996"(positive regulation of lipid catabolic process)|go:"GO:0051384"(response to glucocorticoid)|go:"GO:0055102"(lipase inhibitor activity)|go:"GO:0060192"(negative regulation of lipase activity)|go:"GO:0060228"(phosphatidylcholine-sterol O-acyltransferase activator activity)|go:"GO:0060621"(negative regulation of cholesterol import)|go:"GO:0060695"(negative regulation of cholesterol transporter activity)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070653"(high-density lipoprotein particle receptor binding)|go:"GO:0072562"(blood microparticle)|go:"GO:0120020"(cholesterol transfer activity)|interpro:IPR006801("Apolipoprotein A-II (ApoA-II)")|interpro:IPR036172|mint:P02652|reactome:R-HSA-1989781|reactome:R-HSA-381426|reactome:R-HSA-8957275|reactome:R-HSA-8963888|reactome:R-HSA-8963901|reactome:R-HSA-975634 - - - figure legend:Fig.2A,Supp Table S5|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-testis)|taxid:9606(Homo sapiens) - 2020/03/24 2021/11/30 rogid:ZE4tXTFi7lUCcIbCL4KHzY3a6xM9606 rogid:uTkwkAwBXAMjDt6PkLhEazATi4g9606 rigid:/AFat0DrynAJ5ofEnoPSTThlxCE false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9BY14 uniprotkb:P05090 intact:EBI-12549378|ensembl:ENSP00000472769|uniprotkb:Q7L5R2|uniprotkb:Q9BPY7 intact:EBI-715495|uniprotkb:Q6IBG6|uniprotkb:B2R579|uniprotkb:D3DNW6|ensembl:ENSP00000345179 psi-mi:tx101_human(display_long)|uniprotkb:TEX101(gene name)|psi-mi:TEX101(display_short)|uniprotkb:Cell surface receptor NYD-SP8(gene name synonym)|uniprotkb:SGRG(gene name synonym)|uniprotkb:Scleroderma-associated autoantigen(gene name synonym)|uniprotkb:Spermatogenesis-related gene protein(gene name synonym)|uniprotkb:UNQ867/PRO1884(orf name) psi-mi:apod_human(display_long)|uniprotkb:APOD(gene name)|psi-mi:APOD(display_short) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Schiza et al. (2018) imex:IM-28077|pubmed:30097533 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-25505061|imex:IM-28077-3 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000131126(gene)|ensembl:ENST00000598265(transcript)|go:"GO:0001669"(acrosomal vesicle)|go:"GO:0002080"(acrosomal membrane)|go:"GO:0005576"(extracellular region)|go:"GO:0005886"(plasma membrane)|go:"GO:0007339"(binding of sperm to zona pellucida)|go:"GO:0009566"(fertilization)|go:"GO:0030317"(flagellated sperm motility)|go:"GO:0044853"(plasma membrane raft)|go:"GO:0046658"(anchored component of plasma membrane)|go:"GO:1901317"(regulation of flagellated sperm motility)|interpro:IPR016054(Ly-6 antigen / uPA receptor -like)|rcsb pdb:7BPR|reactome:R-HSA-163125|refseq:NP_001123483.1|refseq:NP_113639.4 refseq:NP_001638.1|go:"GO:0022626"(cytosolic ribosome)|go:"GO:0030425"(dendrite)|go:"GO:0042246"(tissue regeneration)|go:"GO:0042308"(negative regulation of protein import into nucleus)|go:"GO:0042493"|go:"GO:0043025"(neuronal cell body)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0048662"(negative regulation of smooth muscle cell proliferation)|go:"GO:0048678"(response to axon injury)|go:"GO:0051895"(negative regulation of focal adhesion assembly)|go:"GO:0060588"(negative regulation of lipoprotein lipid oxidation)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071638"(negative regulation of monocyte chemotactic protein-1 production)|go:"GO:1900016"(negative regulation of cytokine production involved in inflammatory response)|go:"GO:2000098"(negative regulation of smooth muscle cell-matrix adhesion)|go:"GO:2000405"(negative regulation of T cell migration)|interpro:IPR000566(Lipocalin-related protein and Bos/Can/Equ allergen)|interpro:IPR002969(Apolipoprotein D)|interpro:IPR012674(Calycin)|interpro:IPR022271|interpro:IPR022272|interpro:IPR026222|mint:P05090|rcsb pdb:2APD|rcsb pdb:2HZQ|rcsb pdb:2HZR|reactome:R-HSA-804914|reactome:R-HSA-9029569|go:"GO:0006006"(glucose metabolic process)|go:"GO:0006629"(lipid metabolic process)|go:"GO:0007420"(brain development)|go:"GO:0007568"(aging)|go:"GO:0010642"(negative regulation of platelet-derived growth factor receptor signaling pathway)|go:"GO:0014012"(peripheral nervous system axon regeneration)|go:"GO:0015485"(cholesterol binding)|ensembl:ENSG00000189058(gene)|ensembl:ENST00000343267(transcript)|go:"GO:0000302"(response to reactive oxygen species)|go:"GO:0001525"(angiogenesis)|go:"GO:0005319"(lipid transporter activity)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum) - - - figure legend:Fig.2A,Supp Table S5|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-testis)|taxid:9606(Homo sapiens) - 2020/03/24 2021/11/30 rogid:ZE4tXTFi7lUCcIbCL4KHzY3a6xM9606 rogid:eD7+u5/ZQ5vntlwrq6itkhCxZJU9606 rigid:/AFat0DrynAJ5ofEnoPSTThlxCE false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9BY14 uniprotkb:Q9UBT2 intact:EBI-12549378|ensembl:ENSP00000472769|uniprotkb:Q7L5R2|uniprotkb:Q9BPY7 intact:EBI-718569|uniprotkb:O95605|uniprotkb:Q59H87|uniprotkb:Q6IBP6|uniprotkb:Q9NTJ1|uniprotkb:Q9UED2|uniprotkb:B3KWB9|ensembl:ENSP00000246548 psi-mi:tx101_human(display_long)|uniprotkb:TEX101(gene name)|psi-mi:TEX101(display_short)|uniprotkb:Cell surface receptor NYD-SP8(gene name synonym)|uniprotkb:SGRG(gene name synonym)|uniprotkb:Scleroderma-associated autoantigen(gene name synonym)|uniprotkb:Spermatogenesis-related gene protein(gene name synonym)|uniprotkb:UNQ867/PRO1884(orf name) psi-mi:sae2_human(display_long)|uniprotkb:Ubiquitin-like modifier-activating enzyme 2(gene name synonym)|uniprotkb:HRIHFB2115(orf name)|uniprotkb:Ubiquitin-like 1-activating enzyme E1B(gene name synonym)|uniprotkb:Anthracycline-associated resistance ARX(gene name synonym)|uniprotkb:UBA2(gene name)|psi-mi:UBA2(display_short)|uniprotkb:SAE2(gene name synonym)|uniprotkb:UBLE1B(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Schiza et al. (2018) imex:IM-28077|pubmed:30097533 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-25505061|imex:IM-28077-3 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000131126(gene)|ensembl:ENST00000598265(transcript)|go:"GO:0001669"(acrosomal vesicle)|go:"GO:0002080"(acrosomal membrane)|go:"GO:0005576"(extracellular region)|go:"GO:0005886"(plasma membrane)|go:"GO:0007339"(binding of sperm to zona pellucida)|go:"GO:0009566"(fertilization)|go:"GO:0030317"(flagellated sperm motility)|go:"GO:0044853"(plasma membrane raft)|go:"GO:0046658"(anchored component of plasma membrane)|go:"GO:1901317"(regulation of flagellated sperm motility)|interpro:IPR016054(Ly-6 antigen / uPA receptor -like)|rcsb pdb:7BPR|reactome:R-HSA-163125|refseq:NP_001123483.1|refseq:NP_113639.4 refseq:NP_005490.1|ensembl:ENSP00000246548|ensembl:ENST00000439527|ensembl:ENSP00000437484|interpro:IPR032426|interpro:IPR033127|interpro:IPR035985|interpro:IPR042449|mint:Q9UBT2|rcsb pdb:1Y8Q|rcsb pdb:1Y8R|rcsb pdb:2PX9|rcsb pdb:3KYC|rcsb pdb:3KYD|rcsb pdb:4W5V|rcsb pdb:5FQ2|rcsb pdb:6CWY|rcsb pdb:6CWZ|rcsb pdb:6XOG|rcsb pdb:6XOH|rcsb pdb:6XOI|reactome:R-HSA-3065676|reactome:R-HSA-3065678|ensembl:ENSG00000126261(gene)|ensembl:ENST00000246548(transcript)|go:"GO:0000287"(magnesium ion binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0016740"(transferase activity)|go:"GO:0016925"(protein sumoylation)|go:"GO:0019948"(SUMO activating enzyme activity)|go:"GO:0031510"(SUMO activating enzyme complex)|go:"GO:0032183"(SUMO binding)|go:"GO:0032446"(protein modification by small protein conjugation)|go:"GO:0033235"(positive regulation of protein sumoylation)|go:"GO:0044388"(small protein activating enzyme binding)|go:"GO:0044390"(ubiquitin-like protein conjugating enzyme binding)|go:"GO:0046982"(protein heterodimerization activity)|interpro:IPR000594(UBA/THIF-type NAD/FAD binding fold)|interpro:IPR018074|interpro:IPR023318|interpro:IPR028077|interpro:IPR030661|dip:DIP-35136N - - - figure legend:Fig.2A,Supp Table S5|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-testis)|taxid:9606(Homo sapiens) - 2020/03/24 2021/11/30 rogid:ZE4tXTFi7lUCcIbCL4KHzY3a6xM9606 rogid:OwedW+/kLLyyv1mwI+hjEPet+yM9606 rigid:/AFat0DrynAJ5ofEnoPSTThlxCE false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9BY14 uniprotkb:P14324 intact:EBI-12549378|ensembl:ENSP00000472769|uniprotkb:Q7L5R2|uniprotkb:Q9BPY7 intact:EBI-948245|ensembl:ENSP00000349078|ensembl:ENSP00000357340|uniprotkb:Q96G29|uniprotkb:D3DV91|uniprotkb:E9PCI9 psi-mi:tx101_human(display_long)|uniprotkb:TEX101(gene name)|psi-mi:TEX101(display_short)|uniprotkb:Cell surface receptor NYD-SP8(gene name synonym)|uniprotkb:SGRG(gene name synonym)|uniprotkb:Scleroderma-associated autoantigen(gene name synonym)|uniprotkb:Spermatogenesis-related gene protein(gene name synonym)|uniprotkb:UNQ867/PRO1884(orf name) psi-mi:fpps_human(display_long)|uniprotkb:Farnesyl diphosphate synthase(gene name synonym)|uniprotkb:FDPS(gene name)|psi-mi:FDPS(display_short)|uniprotkb:FPS(gene name synonym)|uniprotkb:KIAA1293(gene name synonym)|uniprotkb:"(2E,6E)-farnesyl diphosphate synthase"(gene name synonym)|uniprotkb:Dimethylallyltranstransferase(gene name synonym)|uniprotkb:Geranyltranstransferase(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Schiza et al. (2018) imex:IM-28077|pubmed:30097533 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-25505061|imex:IM-28077-3 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000131126(gene)|ensembl:ENST00000598265(transcript)|go:"GO:0001669"(acrosomal vesicle)|go:"GO:0002080"(acrosomal membrane)|go:"GO:0005576"(extracellular region)|go:"GO:0005886"(plasma membrane)|go:"GO:0007339"(binding of sperm to zona pellucida)|go:"GO:0009566"(fertilization)|go:"GO:0030317"(flagellated sperm motility)|go:"GO:0044853"(plasma membrane raft)|go:"GO:0046658"(anchored component of plasma membrane)|go:"GO:1901317"(regulation of flagellated sperm motility)|interpro:IPR016054(Ly-6 antigen / uPA receptor -like)|rcsb pdb:7BPR|reactome:R-HSA-163125|refseq:NP_001123483.1|refseq:NP_113639.4 ensembl:ENSG00000160752(gene)|ensembl:ENST00000356657(transcript)|ensembl:ENST00000368356(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0004161"(dimethylallyltranstransferase activity)|go:"GO:0004337"(geranyltranstransferase activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006695"(cholesterol biosynthetic process)|go:"GO:0033384"(geranyl diphosphate biosynthetic process)|go:"GO:0045337"(farnesyl diphosphate biosynthetic process)|go:"GO:0046872"(metal ion binding)|interpro:IPR000092(Polyprenyl synthetase)|interpro:IPR008949(Terpenoid synthase)|interpro:IPR033749|go:"GO:0005654"(nucleoplasm)|rcsb pdb:1YQ7|rcsb pdb:1ZW5|rcsb pdb:2F7M|rcsb pdb:2F89|rcsb pdb:2F8C|rcsb pdb:2F8Z|rcsb pdb:2F92|rcsb pdb:2F94|rcsb pdb:2F9K|rcsb pdb:2OPM|rcsb pdb:2OPN|rcsb pdb:2QIS|rcsb pdb:2RAH|rcsb pdb:2VF6|rcsb pdb:3B7L|rcsb pdb:3CP6|rcsb pdb:3N1V|rcsb pdb:3N1W|rcsb pdb:3N3L|rcsb pdb:3N45|rcsb pdb:3N46|rcsb pdb:1YV5|rcsb pdb:3N49|rcsb pdb:3N5H|rcsb pdb:3N5J|rcsb pdb:3N6K|rcsb pdb:3RYE|rcsb pdb:3S4J|rcsb pdb:4DEM|rcsb pdb:4GA3|rcsb pdb:4H5D|rcsb pdb:4H5E|rcsb pdb:4JVJ|rcsb pdb:4KFA|rcsb pdb:4KPD|rcsb pdb:4KPJ|rcsb pdb:4KQ5|rcsb pdb:4KQS|rcsb pdb:4KQU|rcsb pdb:4L2X|rcsb pdb:4LFV|rcsb pdb:4LPG|rcsb pdb:4LPH|rcsb pdb:4N1Z|rcsb pdb:4N9U|rcsb pdb:4NFI|rcsb pdb:4NFJ|rcsb pdb:4NFK|rcsb pdb:4NG6|rcsb pdb:4NKE|rcsb pdb:4NKF|rcsb pdb:4NUA|rcsb pdb:4OGU|rcsb pdb:4P0V|rcsb pdb:4P0W|rcsb pdb:4P0X|rcsb pdb:4PVX|rcsb pdb:4PVY|rcsb pdb:4H5C|rcsb pdb:4Q23|rcsb pdb:4QPF|rcsb pdb:4QXS|rcsb pdb:4RXA|rcsb pdb:4XQR|rcsb pdb:4XQS|rcsb pdb:4XQT|reactome:R-HSA-2426168|rcsb pdb:5CG6|rcsb pdb:5DGM|rcsb pdb:5CG5|rcsb pdb:5DGN|rcsb pdb:5DGS|rcsb pdb:5DIQ|rcsb pdb:5DJP|rcsb pdb:5DJR|rcsb pdb:5DJV|rcsb pdb:5JA0|rcsb pdb:5JUZ|rcsb pdb:5JV0|rcsb pdb:5JV1|rcsb pdb:5JV2|rcsb pdb:5KSX|rcsb pdb:5YGI|rcsb pdb:6N7Y|rcsb pdb:6N7Z|rcsb pdb:6N82|rcsb pdb:6N83|rcsb pdb:6OAG|rcsb pdb:6OAH|reactome:R-HSA-191273|refseq:NP_001129293.1|refseq:NP_001129294.1|refseq:NP_001229753.1|refseq:NP_001229754.1|refseq:NP_001995.1|refseq:XP_005245019.1|refseq:XP_005245020.1|dip:DIP-50059N - - - figure legend:Fig.2A,Supp Table S5|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-testis)|taxid:9606(Homo sapiens) - 2020/03/24 2021/11/30 rogid:ZE4tXTFi7lUCcIbCL4KHzY3a6xM9606 rogid:cLrS58XE4dKJiiK96hQt7JPO5T89606 rigid:/AFat0DrynAJ5ofEnoPSTThlxCE false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9BY14 uniprotkb:P07602 intact:EBI-12549378|ensembl:ENSP00000472769|uniprotkb:Q7L5R2|uniprotkb:Q9BPY7 intact:EBI-716699|uniprotkb:Q53Y86|uniprotkb:P07292|uniprotkb:P15793|uniprotkb:P78538|uniprotkb:P78541|uniprotkb:P78546|uniprotkb:P78547|uniprotkb:P78558|uniprotkb:Q6IBQ6|uniprotkb:Q92739|uniprotkb:Q92740|uniprotkb:Q92741|uniprotkb:Q92742|ensembl:ENSP00000378394 psi-mi:tx101_human(display_long)|uniprotkb:TEX101(gene name)|psi-mi:TEX101(display_short)|uniprotkb:Cell surface receptor NYD-SP8(gene name synonym)|uniprotkb:SGRG(gene name synonym)|uniprotkb:Scleroderma-associated autoantigen(gene name synonym)|uniprotkb:Spermatogenesis-related gene protein(gene name synonym)|uniprotkb:UNQ867/PRO1884(orf name) psi-mi:sap_human(display_long)|uniprotkb:PSAP(gene name)|psi-mi:PSAP(display_short)|uniprotkb:GLBA(gene name synonym)|uniprotkb:SAP1(gene name synonym)|uniprotkb:Proactivator polypeptide(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Schiza et al. (2018) imex:IM-28077|pubmed:30097533 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-25505061|imex:IM-28077-3 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000131126(gene)|ensembl:ENST00000598265(transcript)|go:"GO:0001669"(acrosomal vesicle)|go:"GO:0002080"(acrosomal membrane)|go:"GO:0005576"(extracellular region)|go:"GO:0005886"(plasma membrane)|go:"GO:0007339"(binding of sperm to zona pellucida)|go:"GO:0009566"(fertilization)|go:"GO:0030317"(flagellated sperm motility)|go:"GO:0044853"(plasma membrane raft)|go:"GO:0046658"(anchored component of plasma membrane)|go:"GO:1901317"(regulation of flagellated sperm motility)|interpro:IPR016054(Ly-6 antigen / uPA receptor -like)|rcsb pdb:7BPR|reactome:R-HSA-163125|refseq:NP_001123483.1|refseq:NP_113639.4 refseq:NP_001035930.1|refseq:NP_001035931.1|refseq:NP_002769.1|ensembl:ENSG00000197746(gene)|ensembl:ENST00000394936(transcript)|go:"GO:0002020"(protease binding)|go:"GO:0005543"(phospholipid binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0005764"(lysosome)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005770"(late endosome)|go:"GO:0005886"(plasma membrane)|go:"GO:0006665"(sphingolipid metabolic process)|go:"GO:0007041"(lysosomal transport)|go:"GO:1905576"(ganglioside GT1b binding)|go:"GO:1905577"(ganglioside GP1c binding)|interpro:IPR003119(Saposin type A)|interpro:IPR007856(Saposin-like type B, 1)|interpro:IPR008138(Saposin-like type B, 2)|interpro:IPR008139(Saposin B)|interpro:IPR008373(Saposin)|interpro:IPR011001(Saposin-like)|interpro:IPR021165|rcsb pdb:1M12|rcsb pdb:1N69|rcsb pdb:1SN6|rcsb pdb:2DOB|rcsb pdb:2GTG|rcsb pdb:2QYP|rcsb pdb:2R0R|rcsb pdb:2R1Q|rcsb pdb:2RB3|rcsb pdb:2Z9A|rcsb pdb:3BQP|rcsb pdb:3BQQ|rcsb pdb:4DDJ|rcsb pdb:4UEX|rcsb pdb:4V2O|rcsb pdb:6SLR|reactome:R-HSA-114608|go:"GO:1905575"(ganglioside GM3 binding)|reactome:R-HSA-1660662|reactome:R-HSA-418594|reactome:R-HSA-6798695|reactome:R-HSA-375276|go:"GO:0007193"(adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway)|go:"GO:0008047"(enzyme activator activity)|go:"GO:0010506"(regulation of autophagy)|go:"GO:0019216"(regulation of lipid metabolic process)|go:"GO:0035577"(azurophil granule membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043202"(lysosomal lumen)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0060736"(prostate gland growth)|go:"GO:0060742"(epithelial cell differentiation involved in prostate gland development)|go:"GO:0062023"(collagen-containing extracellular matrix)|go:"GO:0070062"(extracellular exosome)|go:"GO:0097110"(scaffold protein binding)|go:"GO:1903771"(positive regulation of beta-galactosidase activity)|go:"GO:1905572"(ganglioside GM1 transport to membrane)|go:"GO:1905573"(ganglioside GM1 binding)|go:"GO:1905574"(ganglioside GM2 binding)|dip:DIP-29803N - - - figure legend:Fig.2A,Supp Table S5|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-testis)|taxid:9606(Homo sapiens) - 2020/03/24 2021/11/30 rogid:ZE4tXTFi7lUCcIbCL4KHzY3a6xM9606 rogid:DV9GeJ6/mtgv9nUhsCRYBo19d5g9606 rigid:/AFat0DrynAJ5ofEnoPSTThlxCE false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9BY14 uniprotkb:P37802 intact:EBI-12549378|ensembl:ENSP00000472769|uniprotkb:Q7L5R2|uniprotkb:Q9BPY7 intact:EBI-1056740|intact:EBI-2825986|uniprotkb:Q5JRQ6|uniprotkb:Q5JRQ7|uniprotkb:Q9BUH5|uniprotkb:Q9H4P0|uniprotkb:Q6FGI1|uniprotkb:E9KL39|ensembl:ENSP00000357075|ensembl:ENSP00000357077 psi-mi:tx101_human(display_long)|uniprotkb:TEX101(gene name)|psi-mi:TEX101(display_short)|uniprotkb:Cell surface receptor NYD-SP8(gene name synonym)|uniprotkb:SGRG(gene name synonym)|uniprotkb:Scleroderma-associated autoantigen(gene name synonym)|uniprotkb:Spermatogenesis-related gene protein(gene name synonym)|uniprotkb:UNQ867/PRO1884(orf name) psi-mi:tagl2_human(display_long)|uniprotkb:TAGLN2(gene name)|psi-mi:TAGLN2(display_short)|uniprotkb:KIAA0120(gene name synonym)|uniprotkb:SM22-alpha homolog(gene name synonym)|uniprotkb:CDABP0035(orf name)|uniprotkb:Epididymis tissue protein Li 7e(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Schiza et al. (2018) imex:IM-28077|pubmed:30097533 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-25505061|imex:IM-28077-3 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000131126(gene)|ensembl:ENST00000598265(transcript)|go:"GO:0001669"(acrosomal vesicle)|go:"GO:0002080"(acrosomal membrane)|go:"GO:0005576"(extracellular region)|go:"GO:0005886"(plasma membrane)|go:"GO:0007339"(binding of sperm to zona pellucida)|go:"GO:0009566"(fertilization)|go:"GO:0030317"(flagellated sperm motility)|go:"GO:0044853"(plasma membrane raft)|go:"GO:0046658"(anchored component of plasma membrane)|go:"GO:1901317"(regulation of flagellated sperm motility)|interpro:IPR016054(Ly-6 antigen / uPA receptor -like)|rcsb pdb:7BPR|reactome:R-HSA-163125|refseq:NP_001123483.1|refseq:NP_113639.4 refseq:NP_003555.1|refseq:NP_001264152.1|refseq:NP_001264153.1|ensembl:ENSG00000158710(gene)|ensembl:ENST00000320307(transcript)|ensembl:ENST00000368097(transcript)|go:"GO:0005576"(extracellular region)|go:"GO:0005829"(cytosol)|go:"GO:0030855"(epithelial cell differentiation)|go:"GO:0031982"(vesicle)|go:"GO:0045296"(cadherin binding)|go:"GO:0070062"(extracellular exosome)|interpro:IPR000557(Calponin repeat)|interpro:IPR001061("Transgelin (SM22-alpha)")|interpro:IPR001715(Calponin-like actin-binding)|interpro:IPR003096(SM22/calponin)|interpro:IPR036872|mint:P37802|rcsb pdb:1WYM|reactome:R-HSA-114608 - - - figure legend:Fig.2A,Supp Table S5|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-testis)|taxid:9606(Homo sapiens) - 2020/03/24 2021/11/30 rogid:ZE4tXTFi7lUCcIbCL4KHzY3a6xM9606 rogid:JxbMK5SbZWQd+XA9iYc/xuNaVQc9606 rigid:/AFat0DrynAJ5ofEnoPSTThlxCE false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9BY14 uniprotkb:P07864 intact:EBI-12549378|ensembl:ENSP00000472769|uniprotkb:Q7L5R2|uniprotkb:Q9BPY7 intact:EBI-21716174|uniprotkb:D3DQY4|uniprotkb:Q6GSG8|uniprotkb:Q7Z7J4|ensembl:ENSP00000280704|ensembl:ENSP00000437783 psi-mi:tx101_human(display_long)|uniprotkb:TEX101(gene name)|psi-mi:TEX101(display_short)|uniprotkb:Cell surface receptor NYD-SP8(gene name synonym)|uniprotkb:SGRG(gene name synonym)|uniprotkb:Scleroderma-associated autoantigen(gene name synonym)|uniprotkb:Spermatogenesis-related gene protein(gene name synonym)|uniprotkb:UNQ867/PRO1884(orf name) psi-mi:ldhc_human(display_long)|uniprotkb:Cancer/testis antigen 32(gene name synonym)|uniprotkb:LDH testis subunit(gene name synonym)|uniprotkb:LDH-X(gene name synonym)|uniprotkb:LDHC(gene name)|psi-mi:LDHC(display_short)|uniprotkb:LDH3(gene name synonym)|uniprotkb:LDHX(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Schiza et al. (2018) imex:IM-28077|pubmed:30097533 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-25505061|imex:IM-28077-3 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000131126(gene)|ensembl:ENST00000598265(transcript)|go:"GO:0001669"(acrosomal vesicle)|go:"GO:0002080"(acrosomal membrane)|go:"GO:0005576"(extracellular region)|go:"GO:0005886"(plasma membrane)|go:"GO:0007339"(binding of sperm to zona pellucida)|go:"GO:0009566"(fertilization)|go:"GO:0030317"(flagellated sperm motility)|go:"GO:0044853"(plasma membrane raft)|go:"GO:0046658"(anchored component of plasma membrane)|go:"GO:1901317"(regulation of flagellated sperm motility)|interpro:IPR016054(Ly-6 antigen / uPA receptor -like)|rcsb pdb:7BPR|reactome:R-HSA-163125|refseq:NP_001123483.1|refseq:NP_113639.4 refseq:NP_002292.1|refseq:NP_059144.1|go:"GO:0030317"(flagellated sperm motility)|go:"GO:0031514"(motile cilium)|go:"GO:0070062"(extracellular exosome)|interpro:IPR001236(Lactate/malate dehydrogenase)|interpro:IPR001557(L-lactate/malate dehydrogenase)|interpro:IPR011304(L-lactate dehydrogenase)|interpro:IPR015955(Lactate dehydrogenase/glycoside hydrolase, family 4, C-terminal)|interpro:IPR018177|interpro:IPR022383|interpro:IPR036291|reactome:R-HSA-70268|ensembl:ENSG00000166796(gene)|ensembl:ENST00000280704(transcript)|ensembl:ENST00000541669(transcript)|go:"GO:0004459"(L-lactate dehydrogenase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0005975"(carbohydrate metabolic process)|go:"GO:0006754"(ATP biosynthetic process)|go:"GO:0019244"(lactate biosynthetic process from pyruvate)|go:"GO:0019516"(lactate oxidation) - - - figure legend:Fig.2A,Supp Table S5|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-testis)|taxid:9606(Homo sapiens) - 2020/03/24 2021/11/30 rogid:ZE4tXTFi7lUCcIbCL4KHzY3a6xM9606 rogid:Q8SOlZeihuMeWgII7Thdv8wSwn09606 rigid:/AFat0DrynAJ5ofEnoPSTThlxCE false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9BY14 uniprotkb:Q9H1E5 intact:EBI-12549378|ensembl:ENSP00000472769|uniprotkb:Q7L5R2|uniprotkb:Q9BPY7 intact:EBI-2685885|uniprotkb:Q8N4P7|uniprotkb:Q9ULQ8|uniprotkb:Q8NCC1|uniprotkb:Q9UJA1|ensembl:ENSP00000246024 psi-mi:tx101_human(display_long)|uniprotkb:TEX101(gene name)|psi-mi:TEX101(display_short)|uniprotkb:Cell surface receptor NYD-SP8(gene name synonym)|uniprotkb:SGRG(gene name synonym)|uniprotkb:Scleroderma-associated autoantigen(gene name synonym)|uniprotkb:Spermatogenesis-related gene protein(gene name synonym)|uniprotkb:UNQ867/PRO1884(orf name) psi-mi:tmx4_human(display_long)|uniprotkb:KIAA1162(gene name synonym)|uniprotkb:TXNDC13(gene name synonym)|uniprotkb:Thioredoxin domain-containing protein 13(gene name synonym)|uniprotkb:PSEC0095(orf name)|uniprotkb:UNQ475/PRO938(orf name)|uniprotkb:TMX4(gene name)|psi-mi:TMX4(display_short) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Schiza et al. (2018) imex:IM-28077|pubmed:30097533 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-25505061|imex:IM-28077-3 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000131126(gene)|ensembl:ENST00000598265(transcript)|go:"GO:0001669"(acrosomal vesicle)|go:"GO:0002080"(acrosomal membrane)|go:"GO:0005576"(extracellular region)|go:"GO:0005886"(plasma membrane)|go:"GO:0007339"(binding of sperm to zona pellucida)|go:"GO:0009566"(fertilization)|go:"GO:0030317"(flagellated sperm motility)|go:"GO:0044853"(plasma membrane raft)|go:"GO:0046658"(anchored component of plasma membrane)|go:"GO:1901317"(regulation of flagellated sperm motility)|interpro:IPR016054(Ly-6 antigen / uPA receptor -like)|rcsb pdb:7BPR|reactome:R-HSA-163125|refseq:NP_001123483.1|refseq:NP_113639.4 refseq:NP_066979.2|ensembl:ENSG00000125827(gene)|ensembl:ENST00000246024(transcript)|go:"GO:0005637"(nuclear inner membrane)|go:"GO:0016021"(integral component of membrane)|interpro:IPR013766(Thioredoxin domain)|interpro:IPR017937|interpro:IPR036249 - - - figure legend:Fig.2A,Supp Table S5|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-testis)|taxid:9606(Homo sapiens) - 2020/03/24 2021/11/30 rogid:ZE4tXTFi7lUCcIbCL4KHzY3a6xM9606 rogid:kibr+rQ3S/LSK3dOYtMNtOcIQ2k9606 rigid:/AFat0DrynAJ5ofEnoPSTThlxCE false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9BY14 uniprotkb:Q9H8H3 intact:EBI-12549378|ensembl:ENSP00000472769|uniprotkb:Q7L5R2|uniprotkb:Q9BPY7 intact:EBI-1390168|uniprotkb:Q9H7R3|uniprotkb:Q9UHZ7|uniprotkb:Q9Y422|ensembl:ENSP00000331787|ensembl:ENSP00000447542|ensembl:ENSP00000448785 psi-mi:tx101_human(display_long)|uniprotkb:TEX101(gene name)|psi-mi:TEX101(display_short)|uniprotkb:Cell surface receptor NYD-SP8(gene name synonym)|uniprotkb:SGRG(gene name synonym)|uniprotkb:Scleroderma-associated autoantigen(gene name synonym)|uniprotkb:Spermatogenesis-related gene protein(gene name synonym)|uniprotkb:UNQ867/PRO1884(orf name) psi-mi:met7a_human(display_long)|uniprotkb:Protein AAM-B(gene name synonym)|uniprotkb:METTL7A(gene name)|psi-mi:METTL7A(display_short)|uniprotkb:PRO0066(orf name)|uniprotkb:UNQ1902/PRO4348(orf name) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Schiza et al. (2018) imex:IM-28077|pubmed:30097533 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-25505061|imex:IM-28077-3 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000131126(gene)|ensembl:ENST00000598265(transcript)|go:"GO:0001669"(acrosomal vesicle)|go:"GO:0002080"(acrosomal membrane)|go:"GO:0005576"(extracellular region)|go:"GO:0005886"(plasma membrane)|go:"GO:0007339"(binding of sperm to zona pellucida)|go:"GO:0009566"(fertilization)|go:"GO:0030317"(flagellated sperm motility)|go:"GO:0044853"(plasma membrane raft)|go:"GO:0046658"(anchored component of plasma membrane)|go:"GO:1901317"(regulation of flagellated sperm motility)|interpro:IPR016054(Ly-6 antigen / uPA receptor -like)|rcsb pdb:7BPR|reactome:R-HSA-163125|refseq:NP_001123483.1|refseq:NP_113639.4 refseq:NP_054752.3|refseq:XP_006719395.1|ensembl:ENSG00000185432(gene)|ensembl:ENST00000332160(transcript)|ensembl:ENST00000547104(transcript)|ensembl:ENST00000548553(transcript)|go:"GO:0005576"(extracellular region)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005811"(lipid droplet)|go:"GO:0008168"(methyltransferase activity)|go:"GO:0016020"(membrane)|go:"GO:0032259"(methylation)|go:"GO:1904724"(tertiary granule lumen)|interpro:IPR013216(Methyltransferase type 11)|interpro:IPR029063|mint:Q9H8H3|reactome:R-HSA-6798695 - - - figure legend:Fig.2A,Supp Table S5|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-testis)|taxid:9606(Homo sapiens) - 2020/03/24 2021/11/30 rogid:ZE4tXTFi7lUCcIbCL4KHzY3a6xM9606 rogid:b8PnE+BClVn1MzOlg0uIaqDSOaU9606 rigid:/AFat0DrynAJ5ofEnoPSTThlxCE false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9BY14 uniprotkb:Q01650 intact:EBI-12549378|ensembl:ENSP00000472769|uniprotkb:Q7L5R2|uniprotkb:Q9BPY7 intact:EBI-6138761|uniprotkb:Q8IV97|uniprotkb:Q9UBN8|uniprotkb:Q9UP15|uniprotkb:Q9UQC0|ensembl:ENSP00000261622 psi-mi:tx101_human(display_long)|uniprotkb:TEX101(gene name)|psi-mi:TEX101(display_short)|uniprotkb:Cell surface receptor NYD-SP8(gene name synonym)|uniprotkb:SGRG(gene name synonym)|uniprotkb:Scleroderma-associated autoantigen(gene name synonym)|uniprotkb:Spermatogenesis-related gene protein(gene name synonym)|uniprotkb:UNQ867/PRO1884(orf name) psi-mi:lat1_human(display_long)|uniprotkb:SLC7A5(gene name)|psi-mi:SLC7A5(display_short)|uniprotkb:CD98LC(gene name synonym)|uniprotkb:LAT1(gene name synonym)|uniprotkb:MPE16(gene name synonym)|uniprotkb:4F2 light chain(gene name synonym)|uniprotkb:CD98 light chain(gene name synonym)|uniprotkb:Integral membrane protein E16(gene name synonym)|uniprotkb:L-type amino acid transporter 1(gene name synonym)|uniprotkb:Solute carrier family 7 member 5(gene name synonym)|uniprotkb:y+ system cationic amino acid transporter(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Schiza et al. (2018) imex:IM-28077|pubmed:30097533 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-25505061|imex:IM-28077-3 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000131126(gene)|ensembl:ENST00000598265(transcript)|go:"GO:0001669"(acrosomal vesicle)|go:"GO:0002080"(acrosomal membrane)|go:"GO:0005576"(extracellular region)|go:"GO:0005886"(plasma membrane)|go:"GO:0007339"(binding of sperm to zona pellucida)|go:"GO:0009566"(fertilization)|go:"GO:0030317"(flagellated sperm motility)|go:"GO:0044853"(plasma membrane raft)|go:"GO:0046658"(anchored component of plasma membrane)|go:"GO:1901317"(regulation of flagellated sperm motility)|interpro:IPR016054(Ly-6 antigen / uPA receptor -like)|rcsb pdb:7BPR|reactome:R-HSA-163125|refseq:NP_001123483.1|refseq:NP_113639.4 refseq:NP_003477.4|ensembl:ENSG00000103257(gene)|ensembl:ENST00000261622(transcript)|go:"GO:0002720"(positive regulation of cytokine production involved in immune response)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0009925"(basal plasma membrane)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0015171"(amino acid transmembrane transporter activity)|go:"GO:0015173"(aromatic amino acid transmembrane transporter activity)|go:"GO:0015175"(neutral amino acid transmembrane transporter activity)|go:"GO:0015179"(L-amino acid transmembrane transporter activity)|go:"GO:0015190"(L-leucine transmembrane transporter activity)|go:"GO:0015196"(L-tryptophan transmembrane transporter activity)|go:"GO:0015349"(thyroid hormone transmembrane transporter activity)|go:"GO:0015823"(phenylalanine transport)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0031528"(microvillus membrane)|go:"GO:0032729"(positive regulation of interferon-gamma production)|go:"GO:0032740"(positive regulation of interleukin-17 production)|go:"GO:0032753"(positive regulation of interleukin-4 production)|go:"GO:0042605"(peptide antigen binding)|go:"GO:0042908"(xenobiotic transport)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070327"(thyroid hormone transport)|go:"GO:0089718"(amino acid import across plasma membrane)|go:"GO:0098591"(external side of apical plasma membrane)|go:"GO:0098713"(leucine import across plasma membrane)|go:"GO:0150104"(transport across blood-brain barrier)|go:"GO:1903801"(L-leucine import across plasma membrane)|go:"GO:1904556"(L-tryptophan transmembrane transport)|go:"GO:1990184"(amino acid transport complex)|interpro:IPR002293(Amino acid/polyamine transporter I)|interpro:IPR004760(L-type amino acid transporter)|mint:Q01650|rcsb pdb:6IRS|rcsb pdb:6IRT|rcsb pdb:6JMQ|rcsb pdb:7DSK|rcsb pdb:7DSL|rcsb pdb:7DSN|rcsb pdb:7DSQ|reactome:R-HSA-210991|reactome:R-HSA-352230|reactome:R-HSA-71240|go:"GO:0015804"(neutral amino acid transport) - - - figure legend:Fig.2A,Supp Table S5|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-testis)|taxid:9606(Homo sapiens) - 2020/03/24 2021/11/30 rogid:ZE4tXTFi7lUCcIbCL4KHzY3a6xM9606 rogid:GrXTCUhrHMNCnvscgx1ink2opoU9606 rigid:/AFat0DrynAJ5ofEnoPSTThlxCE false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9BY14 uniprotkb:P13473 intact:EBI-12549378|ensembl:ENSP00000472769|uniprotkb:Q7L5R2|uniprotkb:Q9BPY7 intact:EBI-2907154|uniprotkb:A8K4X5|uniprotkb:Q16641|uniprotkb:Q96J30|uniprotkb:Q99534|uniprotkb:Q9UD93|uniprotkb:D3DTF0|intact:EBI-4324646|uniprotkb:Q6Q3G8|ensembl:ENSP00000200639 psi-mi:tx101_human(display_long)|uniprotkb:TEX101(gene name)|psi-mi:TEX101(display_short)|uniprotkb:Cell surface receptor NYD-SP8(gene name synonym)|uniprotkb:SGRG(gene name synonym)|uniprotkb:Scleroderma-associated autoantigen(gene name synonym)|uniprotkb:Spermatogenesis-related gene protein(gene name synonym)|uniprotkb:UNQ867/PRO1884(orf name) psi-mi:lamp2_human(display_long)|uniprotkb:LAMP2(gene name)|psi-mi:LAMP2(display_short)|uniprotkb:CD107 antigen-like family member B(gene name synonym)|uniprotkb:LGP-96(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Schiza et al. (2018) imex:IM-28077|pubmed:30097533 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-25505061|imex:IM-28077-3 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000131126(gene)|ensembl:ENST00000598265(transcript)|go:"GO:0001669"(acrosomal vesicle)|go:"GO:0002080"(acrosomal membrane)|go:"GO:0005576"(extracellular region)|go:"GO:0005886"(plasma membrane)|go:"GO:0007339"(binding of sperm to zona pellucida)|go:"GO:0009566"(fertilization)|go:"GO:0030317"(flagellated sperm motility)|go:"GO:0044853"(plasma membrane raft)|go:"GO:0046658"(anchored component of plasma membrane)|go:"GO:1901317"(regulation of flagellated sperm motility)|interpro:IPR016054(Ly-6 antigen / uPA receptor -like)|rcsb pdb:7BPR|reactome:R-HSA-163125|refseq:NP_001123483.1|refseq:NP_113639.4 refseq:NP_002285.1|refseq:NP_054701.1|refseq:NP_001116078.1|ensembl:ENSG00000005893(gene)|ensembl:ENST00000200639(transcript)|go:"GO:0005615"(extracellular space)|go:"GO:0005764"(lysosome)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005770"(late endosome)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0005886"(plasma membrane)|go:"GO:0006605"(protein targeting)|go:"GO:0009267"(cellular response to starvation)|go:"GO:0016020"(membrane)|go:"GO:0017038"(protein import)|go:"GO:0019899"(enzyme binding)|go:"GO:0031088"(platelet dense granule membrane)|go:"GO:0031333"(negative regulation of protein-containing complex assembly)|go:"GO:0031647"(regulation of protein stability)|go:"GO:0031902"(late endosome membrane)|go:"GO:0035577"(azurophil granule membrane)|go:"GO:0043202"(lysosomal lumen)|go:"GO:0044754"(autolysosome)|go:"GO:0045121"(membrane raft)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0050821"(protein stabilization)|go:"GO:0061684"(chaperone-mediated autophagy)|go:"GO:0061740"(protein targeting to lysosome involved in chaperone-mediated autophagy)|go:"GO:0061742"(chaperone-mediated autophagy translocation complex)|go:"GO:0070062"(extracellular exosome)|go:"GO:0072594"(establishment of protein localization to organelle)|go:"GO:0097352"(autophagosome maturation)|go:"GO:0097637"(integral component of autophagosome membrane)|go:"GO:0101003"(ficolin-1-rich granule membrane)|go:"GO:1905146"(lysosomal protein catabolic process)|go:"GO:1990836"(lysosomal matrix)|interpro:IPR002000("Lysosome-associated membrane glycoprotein (Lamp)/CD68")|interpro:IPR018134|mint:P13473|rcsb pdb:2MOF|rcsb pdb:2MOM|reactome:R-HSA-114608|reactome:R-HSA-6798695|reactome:R-HSA-9613829 - - - figure legend:Fig.2A,Supp Table S5|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-testis)|taxid:9606(Homo sapiens) - 2020/03/24 2021/11/30 rogid:ZE4tXTFi7lUCcIbCL4KHzY3a6xM9606 rogid:+s4K/qoL3PBwjATJmFDQtqcl/ZQ9606 rigid:/AFat0DrynAJ5ofEnoPSTThlxCE false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9BY14 uniprotkb:P00387 intact:EBI-12549378|ensembl:ENSP00000472769|uniprotkb:Q7L5R2|uniprotkb:Q9BPY7 intact:EBI-1046040|uniprotkb:O75675|uniprotkb:Q8TDL8|uniprotkb:Q8WTS8|uniprotkb:Q9UEN4|uniprotkb:Q9UEN5|uniprotkb:Q9UL55|uniprotkb:Q9UL56|uniprotkb:B1AHF2|uniprotkb:B7Z7L3|ensembl:ENSP00000338461 psi-mi:tx101_human(display_long)|uniprotkb:TEX101(gene name)|psi-mi:TEX101(display_short)|uniprotkb:Cell surface receptor NYD-SP8(gene name synonym)|uniprotkb:SGRG(gene name synonym)|uniprotkb:Scleroderma-associated autoantigen(gene name synonym)|uniprotkb:Spermatogenesis-related gene protein(gene name synonym)|uniprotkb:UNQ867/PRO1884(orf name) psi-mi:nb5r3_human(display_long)|uniprotkb:Diaphorase-1(gene name synonym)|uniprotkb:CYB5R3(gene name)|psi-mi:CYB5R3(display_short)|uniprotkb:DIA1(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Schiza et al. (2018) imex:IM-28077|pubmed:30097533 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-25505061|imex:IM-28077-3 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000131126(gene)|ensembl:ENST00000598265(transcript)|go:"GO:0001669"(acrosomal vesicle)|go:"GO:0002080"(acrosomal membrane)|go:"GO:0005576"(extracellular region)|go:"GO:0005886"(plasma membrane)|go:"GO:0007339"(binding of sperm to zona pellucida)|go:"GO:0009566"(fertilization)|go:"GO:0030317"(flagellated sperm motility)|go:"GO:0044853"(plasma membrane raft)|go:"GO:0046658"(anchored component of plasma membrane)|go:"GO:1901317"(regulation of flagellated sperm motility)|interpro:IPR016054(Ly-6 antigen / uPA receptor -like)|rcsb pdb:7BPR|reactome:R-HSA-163125|refseq:NP_001123483.1|refseq:NP_113639.4 refseq:NP_001165132.1|refseq:NP_000389.1|refseq:NP_001123291.1|refseq:NP_015565.1|refseq:NP_001165131.1|ensembl:ENSG00000100243(gene)|ensembl:ENST00000352397(transcript)|go:"GO:0004128"("cytochrome-b5 reductase activity, acting on NAD(P)H")|go:"GO:0005576"(extracellular region)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005811"(lipid droplet)|go:"GO:0005833"(hemoglobin complex)|go:"GO:0006695"(cholesterol biosynthetic process)|go:"GO:0006809"(nitric oxide biosynthetic process)|go:"GO:0008015"(blood circulation)|go:"GO:0016020"(membrane)|go:"GO:0016208"(AMP binding)|go:"GO:0035578"(azurophil granule lumen)|go:"GO:0043531"(ADP binding)|go:"GO:0051287"(NAD binding)|go:"GO:0071949"(FAD binding)|go:"GO:1903958"(nitric-oxide synthase complex)|interpro:IPR001433("Oxidoreductase FAD/NAD(P)-binding")|interpro:IPR001709(Flavoprotein pyridine nucleotide cytochrome reductase)|interpro:IPR001834("NADH:cytochrome b5 reductase (CBR)")|interpro:IPR008333(Oxidoreductase FAD-binding region)|interpro:IPR017927|interpro:IPR017938|mint:P00387|rcsb pdb:1M91|rcsb pdb:1UMK|reactome:R-HSA-196836|reactome:R-HSA-211945|reactome:R-HSA-6798695|interpro:IPR039261|dip:DIP-50463N - - - figure legend:Fig.2A,Supp Table S5|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-testis)|taxid:9606(Homo sapiens) - 2020/03/24 2021/11/30 rogid:ZE4tXTFi7lUCcIbCL4KHzY3a6xM9606 rogid:Q8JTO6AXZ8LE4FXZAzOw2p4b6HY9606 rigid:/AFat0DrynAJ5ofEnoPSTThlxCE false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9BY14 uniprotkb:P04844 intact:EBI-12549378|ensembl:ENSP00000472769|uniprotkb:Q7L5R2|uniprotkb:Q9BPY7 intact:EBI-719731|uniprotkb:Q5JYR6|uniprotkb:Q9UBE1|uniprotkb:Q6IBA5|uniprotkb:Q96E21|uniprotkb:Q9BUQ3|ensembl:ENSP00000237530 psi-mi:tx101_human(display_long)|uniprotkb:TEX101(gene name)|psi-mi:TEX101(display_short)|uniprotkb:Cell surface receptor NYD-SP8(gene name synonym)|uniprotkb:SGRG(gene name synonym)|uniprotkb:Scleroderma-associated autoantigen(gene name synonym)|uniprotkb:Spermatogenesis-related gene protein(gene name synonym)|uniprotkb:UNQ867/PRO1884(orf name) psi-mi:rpn2_human(display_long)|uniprotkb:Dolichyl-diphosphooligosaccharide--protein glycosyltransferase 63 kDa subunit(gene name synonym)|uniprotkb:Ribophorin-2(gene name synonym)|uniprotkb:Ribophorin II(gene name synonym)|uniprotkb:RIBIIR(gene name synonym)|uniprotkb:RPN2(gene name)|psi-mi:RPN2(display_short) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Schiza et al. (2018) imex:IM-28077|pubmed:30097533 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-25505061|imex:IM-28077-3 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000131126(gene)|ensembl:ENST00000598265(transcript)|go:"GO:0001669"(acrosomal vesicle)|go:"GO:0002080"(acrosomal membrane)|go:"GO:0005576"(extracellular region)|go:"GO:0005886"(plasma membrane)|go:"GO:0007339"(binding of sperm to zona pellucida)|go:"GO:0009566"(fertilization)|go:"GO:0030317"(flagellated sperm motility)|go:"GO:0044853"(plasma membrane raft)|go:"GO:0046658"(anchored component of plasma membrane)|go:"GO:1901317"(regulation of flagellated sperm motility)|interpro:IPR016054(Ly-6 antigen / uPA receptor -like)|rcsb pdb:7BPR|reactome:R-HSA-163125|refseq:NP_001123483.1|refseq:NP_113639.4 refseq:NP_001129243.1|refseq:NP_002942.2|ensembl:ENSG00000118705(gene)|ensembl:ENST00000237530(transcript)|go:"GO:0000421"(autophagosome membrane)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005791"(rough endoplasmic reticulum)|go:"GO:0006464"(cellular protein modification process)|go:"GO:0006487"(protein N-linked glycosylation)|go:"GO:0007568"(aging)|go:"GO:0008250"(oligosaccharyltransferase complex)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016604"(nuclear body)|go:"GO:0018279"(protein N-linked glycosylation via asparagine)|go:"GO:0042493"|go:"GO:0043022"(ribosome binding)|interpro:IPR008814(Ribophorin II)|mint:P04844|rcsb pdb:6S7O|rcsb pdb:6S7T|reactome:R-HSA-1799339|reactome:R-HSA-446203|reactome:R-HSA-9694548|refseq:NP_001311234.1|refseq:NP_001311235.1|refseq:NP_001311228.1|refseq:NP_001311230.1|refseq:NP_001311231.1|refseq:NP_001311232.1|refseq:NP_001311233.1 - - - figure legend:Fig.2A,Supp Table S5|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-testis)|taxid:9606(Homo sapiens) - 2020/03/24 2021/11/30 rogid:ZE4tXTFi7lUCcIbCL4KHzY3a6xM9606 rogid:7bTuuEb3ykWQvkI/5DKpga48s/w9606 rigid:/AFat0DrynAJ5ofEnoPSTThlxCE false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9BY14 uniprotkb:P02656 intact:EBI-12549378|ensembl:ENSP00000472769|uniprotkb:Q7L5R2|uniprotkb:Q9BPY7 intact:EBI-1220113|uniprotkb:Q08E83|uniprotkb:Q6Q786|ensembl:ENSP00000227667 psi-mi:tx101_human(display_long)|uniprotkb:TEX101(gene name)|psi-mi:TEX101(display_short)|uniprotkb:Cell surface receptor NYD-SP8(gene name synonym)|uniprotkb:SGRG(gene name synonym)|uniprotkb:Scleroderma-associated autoantigen(gene name synonym)|uniprotkb:Spermatogenesis-related gene protein(gene name synonym)|uniprotkb:UNQ867/PRO1884(orf name) psi-mi:apoc3_human(display_long)|uniprotkb:APOC3(gene name)|psi-mi:APOC3(display_short)|uniprotkb:Apolipoprotein C3(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Schiza et al. (2018) imex:IM-28077|pubmed:30097533 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-25505061|imex:IM-28077-3 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000131126(gene)|ensembl:ENST00000598265(transcript)|go:"GO:0001669"(acrosomal vesicle)|go:"GO:0002080"(acrosomal membrane)|go:"GO:0005576"(extracellular region)|go:"GO:0005886"(plasma membrane)|go:"GO:0007339"(binding of sperm to zona pellucida)|go:"GO:0009566"(fertilization)|go:"GO:0030317"(flagellated sperm motility)|go:"GO:0044853"(plasma membrane raft)|go:"GO:0046658"(anchored component of plasma membrane)|go:"GO:1901317"(regulation of flagellated sperm motility)|interpro:IPR016054(Ly-6 antigen / uPA receptor -like)|rcsb pdb:7BPR|reactome:R-HSA-163125|refseq:NP_001123483.1|refseq:NP_113639.4 refseq:NP_000031.1|ensembl:ENSG00000110245(gene)|ensembl:ENST00000227667(transcript)|go:"GO:0005543"(phospholipid binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0005769"(early endosome)|go:"GO:0006641"(triglyceride metabolic process)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0010897"(negative regulation of triglyceride catabolic process)|go:"GO:0010903"(negative regulation of very-low-density lipoprotein particle remodeling)|go:"GO:0010916"(negative regulation of very-low-density lipoprotein particle clearance)|go:"GO:0010987"(negative regulation of high-density lipoprotein particle clearance)|go:"GO:0010989"(negative regulation of low-density lipoprotein particle clearance)|go:"GO:0015485"(cholesterol binding)|go:"GO:0019433"(triglyceride catabolic process)|go:"GO:0030234"(enzyme regulator activity)|go:"GO:0032489"(regulation of Cdc42 protein signal transduction)|go:"GO:0033344"(cholesterol efflux)|go:"GO:0033700"(phospholipid efflux)|go:"GO:0034361"(very-low-density lipoprotein particle)|go:"GO:0034363"(intermediate-density lipoprotein particle)|go:"GO:0034366"(spherical high-density lipoprotein particle)|go:"GO:0034375"(high-density lipoprotein particle remodeling)|go:"GO:0034379"(very-low-density lipoprotein particle assembly)|go:"GO:0034382"(chylomicron remnant clearance)|go:"GO:0042157"(lipoprotein metabolic process)|go:"GO:0042627"(chylomicron)|go:"GO:0042632"(cholesterol homeostasis)|go:"GO:0043691"(reverse cholesterol transport)|go:"GO:0045717"(negative regulation of fatty acid biosynthetic process)|go:"GO:0045833"(negative regulation of lipid metabolic process)|go:"GO:0048261"(negative regulation of receptor-mediated endocytosis)|go:"GO:0050995"(negative regulation of lipid catabolic process)|go:"GO:0051005"(negative regulation of lipoprotein lipase activity)|go:"GO:0055102"(lipase inhibitor activity)|go:"GO:0060621"(negative regulation of cholesterol import)|go:"GO:0062023"(collagen-containing extracellular matrix)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070328"(triglyceride homeostasis)|go:"GO:0070653"(high-density lipoprotein particle receptor binding)|interpro:IPR008403(Apolipoprotein CIII)|interpro:IPR038195|mint:P02656|rcsb pdb:2JQ3|reactome:R-HSA-8963888|reactome:R-HSA-8963901|reactome:R-HSA-8964058|reactome:R-HSA-975634 - - - figure legend:Fig.2A,Supp Table S5|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-testis)|taxid:9606(Homo sapiens) - 2020/03/24 2021/11/30 rogid:ZE4tXTFi7lUCcIbCL4KHzY3a6xM9606 rogid:DDj33pQWDh0i5+mwMy16Dmg6JPg9606 rigid:/AFat0DrynAJ5ofEnoPSTThlxCE false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9BY14 uniprotkb:Q14240 intact:EBI-12549378|ensembl:ENSP00000472769|uniprotkb:Q7L5R2|uniprotkb:Q9BPY7 intact:EBI-73473|intact:EBI-1058347|uniprotkb:Q96B90|uniprotkb:Q96EA8|intact:EBI-2831835|uniprotkb:Q53XJ6|uniprotkb:D3DNU9|ensembl:ENSP00000326381 psi-mi:tx101_human(display_long)|uniprotkb:TEX101(gene name)|psi-mi:TEX101(display_short)|uniprotkb:Cell surface receptor NYD-SP8(gene name synonym)|uniprotkb:SGRG(gene name synonym)|uniprotkb:Scleroderma-associated autoantigen(gene name synonym)|uniprotkb:Spermatogenesis-related gene protein(gene name synonym)|uniprotkb:UNQ867/PRO1884(orf name) psi-mi:if4a2_human(display_long)|uniprotkb:ATP-dependent RNA helicase eIF4A-2(gene name synonym)|uniprotkb:EIF4A2(gene name)|psi-mi:EIF4A2(display_short)|uniprotkb:DDX2B(gene name synonym)|uniprotkb:EIF4F(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Schiza et al. (2018) imex:IM-28077|pubmed:30097533 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-25505061|imex:IM-28077-3 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000131126(gene)|ensembl:ENST00000598265(transcript)|go:"GO:0001669"(acrosomal vesicle)|go:"GO:0002080"(acrosomal membrane)|go:"GO:0005576"(extracellular region)|go:"GO:0005886"(plasma membrane)|go:"GO:0007339"(binding of sperm to zona pellucida)|go:"GO:0009566"(fertilization)|go:"GO:0030317"(flagellated sperm motility)|go:"GO:0044853"(plasma membrane raft)|go:"GO:0046658"(anchored component of plasma membrane)|go:"GO:1901317"(regulation of flagellated sperm motility)|interpro:IPR016054(Ly-6 antigen / uPA receptor -like)|rcsb pdb:7BPR|reactome:R-HSA-163125|refseq:NP_001123483.1|refseq:NP_113639.4 refseq:NP_001958.2|ensembl:ENSG00000156976(gene)|ensembl:ENST00000323963(transcript)|go:"GO:0002183"(cytoplasmic translational initiation)|go:"GO:0003723"(RNA binding)|go:"GO:0003724"(RNA helicase activity)|go:"GO:0003743"(translation initiation factor activity)|go:"GO:0004386"(helicase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005829"(cytosol)|go:"GO:0006446"(regulation of translational initiation)|go:"GO:0016281"(eukaryotic translation initiation factor 4F complex)|go:"GO:0016887"(ATP hydrolysis activity)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|go:"GO:1900260"(negative regulation of RNA-directed 5'-3' RNA polymerase activity)|go:"GO:1990830"(cellular response to leukemia inhibitory factor)|interpro:IPR000629(RNA helicase, ATP-dependent, DEAD-box, conserved site)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR011545(DNA/RNA helicase, DEAD/DEAH box type, N-terminal)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR014014(RNA helicase, DEAD-box type, Q motif)|interpro:IPR027417|interpro:IPR044728|mint:Q14240|rcsb pdb:3BOR|reactome:R-HSA-1169408|reactome:R-HSA-156827|reactome:R-HSA-429947|reactome:R-HSA-72649|reactome:R-HSA-72662|reactome:R-HSA-72702|reactome:R-HSA-72706 - - - figure legend:Fig.2A,Supp Table S5|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-testis)|taxid:9606(Homo sapiens) - 2020/03/24 2021/11/30 rogid:ZE4tXTFi7lUCcIbCL4KHzY3a6xM9606 rogid:m9i/jWfsbU+6kQvj1h06x31+awg9606 rigid:/AFat0DrynAJ5ofEnoPSTThlxCE false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9BY14 uniprotkb:P02647 intact:EBI-12549378|ensembl:ENSP00000472769|uniprotkb:Q7L5R2|uniprotkb:Q9BPY7 intact:EBI-701692|uniprotkb:Q6LDN9|uniprotkb:Q6Q785|uniprotkb:A8K866|uniprotkb:Q9UCS8|uniprotkb:Q9UCT8|ensembl:ENSP00000236850|ensembl:ENSP00000352471|ensembl:ENSP00000364469|ensembl:ENSP00000364472 psi-mi:tx101_human(display_long)|uniprotkb:TEX101(gene name)|psi-mi:TEX101(display_short)|uniprotkb:Cell surface receptor NYD-SP8(gene name synonym)|uniprotkb:SGRG(gene name synonym)|uniprotkb:Scleroderma-associated autoantigen(gene name synonym)|uniprotkb:Spermatogenesis-related gene protein(gene name synonym)|uniprotkb:UNQ867/PRO1884(orf name) psi-mi:apoa1_human(display_long)|uniprotkb:APOA1(gene name)|psi-mi:APOA1(display_short)|uniprotkb:Apolipoprotein A1(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Schiza et al. (2018) imex:IM-28077|pubmed:30097533 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-25505061|imex:IM-28077-3 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000131126(gene)|ensembl:ENST00000598265(transcript)|go:"GO:0001669"(acrosomal vesicle)|go:"GO:0002080"(acrosomal membrane)|go:"GO:0005576"(extracellular region)|go:"GO:0005886"(plasma membrane)|go:"GO:0007339"(binding of sperm to zona pellucida)|go:"GO:0009566"(fertilization)|go:"GO:0030317"(flagellated sperm motility)|go:"GO:0044853"(plasma membrane raft)|go:"GO:0046658"(anchored component of plasma membrane)|go:"GO:1901317"(regulation of flagellated sperm motility)|interpro:IPR016054(Ly-6 antigen / uPA receptor -like)|rcsb pdb:7BPR|reactome:R-HSA-163125|refseq:NP_001123483.1|refseq:NP_113639.4 refseq:NP_000030.1|refseq:NP_001304946.1|refseq:NP_001304947.1|refseq:NP_001304950.1|dip:DIP-29619N|ensembl:ENSG00000118137(gene)|ensembl:ENST00000236850(transcript)|ensembl:ENST00000359492(transcript)|ensembl:ENST00000375320(transcript)|ensembl:ENST00000375323(transcript)|go:"GO:0001540"(amyloid-beta binding)|go:"GO:0001932"(regulation of protein phosphorylation)|go:"GO:0001935"(endothelial cell proliferation)|go:"GO:0002719"(negative regulation of cytokine production involved in immune response)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005543"(phospholipid binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0005634"(nucleus)|go:"GO:0005769"(early endosome)|go:"GO:0005788"(endoplasmic reticulum lumen)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006656"(phosphatidylcholine biosynthetic process)|go:"GO:0006695"(cholesterol biosynthetic process)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0007229"(integrin-mediated signaling pathway)|go:"GO:0007584"(response to nutrient)|go:"GO:0008035"(high-density lipoprotein particle binding)|go:"GO:0008203"(cholesterol metabolic process)|go:"GO:0008211"(glucocorticoid metabolic process)|go:"GO:0009986"(cell surface)|go:"GO:0010804"(negative regulation of tumor necrosis factor-mediated signaling pathway)|go:"GO:0010873"(positive regulation of cholesterol esterification)|go:"GO:0010875"(positive regulation of cholesterol efflux)|go:"GO:0010898"(positive regulation of triglyceride catabolic process)|go:"GO:0010903"(negative regulation of very-low-density lipoprotein particle remodeling)|go:"GO:0014012"(peripheral nervous system axon regeneration)|go:"GO:0015485"(cholesterol binding)|go:"GO:0018158"(protein oxidation)|go:"GO:0018206"(peptidyl-methionine modification)|go:"GO:0019899"(enzyme binding)|go:"GO:0019915"(lipid storage)|go:"GO:0030139"(endocytic vesicle)|go:"GO:0030300"(regulation of intestinal cholesterol absorption)|go:"GO:0030301"(cholesterol transport)|go:"GO:0030325"(adrenal gland development)|go:"GO:0031072"(heat shock protein binding)|go:"GO:0031100"(animal organ regeneration)|go:"GO:0031210"(phosphatidylcholine binding)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0032489"(regulation of Cdc42 protein signal transduction)|go:"GO:0032691"(negative regulation of interleukin-1 beta production)|go:"GO:0033344"(cholesterol efflux)|go:"GO:0033700"(phospholipid efflux)|go:"GO:0034115"(negative regulation of heterotypic cell-cell adhesion)|go:"GO:0034190"(apolipoprotein receptor binding)|go:"GO:0034191"(apolipoprotein A-I receptor binding)|go:"GO:0034361"(very-low-density lipoprotein particle)|go:"GO:0034362"(low-density lipoprotein particle)|go:"GO:0034363"(intermediate-density lipoprotein particle)|go:"GO:0034364"(high-density lipoprotein particle)|go:"GO:0034365"(discoidal high-density lipoprotein particle)|go:"GO:0034366"(spherical high-density lipoprotein particle)|go:"GO:0034372"(very-low-density lipoprotein particle remodeling)|go:"GO:0034375"(high-density lipoprotein particle remodeling)|go:"GO:0034380"(high-density lipoprotein particle assembly)|go:"GO:0034384"(high-density lipoprotein particle clearance)|go:"GO:0034774"(secretory granule lumen)|go:"GO:0035025"(positive regulation of Rho protein signal transduction)|go:"GO:0042157"(lipoprotein metabolic process)|go:"GO:0042158"(lipoprotein biosynthetic process)|go:"GO:0042493"|go:"GO:0042627"(chylomicron)|go:"GO:0042632"(cholesterol homeostasis)|go:"GO:0042802"(identical protein binding)|go:"GO:0043534"(blood vessel endothelial cell migration)|go:"GO:0043627"(response to estrogen)|go:"GO:0043691"(reverse cholesterol transport)|go:"GO:0045499"(chemorepellent activity)|go:"GO:0045723"(positive regulation of fatty acid biosynthetic process)|go:"GO:0046470"(phosphatidylcholine metabolic process)|go:"GO:0046889"(positive regulation of lipid biosynthetic process)|go:"GO:0050728"(negative regulation of inflammatory response)|go:"GO:0050766"(positive regulation of phagocytosis)|go:"GO:0050821"(protein stabilization)|go:"GO:0050919"(negative chemotaxis)|go:"GO:0051006"(positive regulation of lipoprotein lipase activity)|go:"GO:0051180"(vitamin transport)|go:"GO:0051345"(positive regulation of hydrolase activity)|go:"GO:0051496"(positive regulation of stress fiber assembly)|go:"GO:0055091"(phospholipid homeostasis)|go:"GO:0055102"(lipase inhibitor activity)|go:"GO:0060192"(negative regulation of lipase activity)|go:"GO:0060228"(phosphatidylcholine-sterol O-acyltransferase activator activity)|go:"GO:0060354"(negative regulation of cell adhesion molecule production)|go:"GO:0060761"(negative regulation of response to cytokine stimulus)|go:"GO:0062023"(collagen-containing extracellular matrix)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070328"(triglyceride homeostasis)|go:"GO:0070508"(cholesterol import)|go:"GO:0070653"(high-density lipoprotein particle receptor binding)|go:"GO:0071682"(endocytic vesicle lumen)|go:"GO:0072562"(blood microparticle)|go:"GO:0120020"(cholesterol transfer activity)|go:"GO:1900026"(positive regulation of substrate adhesion-dependent cell spreading)|go:"GO:1902995"(positive regulation of phospholipid efflux)|go:"GO:1903561"(extracellular vesicle)|interpro:IPR000074(Apolipoprotein A1/A4/E)|mint:P02647|rcsb pdb:1AV1|rcsb pdb:1GW3|rcsb pdb:1GW4|rcsb pdb:1ODP|rcsb pdb:1ODQ|rcsb pdb:1ODR|rcsb pdb:2MSC|rcsb pdb:2MSD|rcsb pdb:2MSE|rcsb pdb:2N5E|rcsb pdb:3K2S|rcsb pdb:3R2P|rcsb pdb:4V6M|rcsb pdb:6CC9|rcsb pdb:6CCH|rcsb pdb:6CCX|rcsb pdb:6CLZ|rcsb pdb:6CM1|rcsb pdb:6PTS|rcsb pdb:6PTW|rcsb pdb:6W4E|rcsb pdb:6W4F|rcsb pdb:7KJR|reactome:R-HSA-114608|reactome:R-HSA-1369062|reactome:R-HSA-1989781|reactome:R-HSA-2168880|reactome:R-HSA-3000471|reactome:R-HSA-3000480|reactome:R-HSA-381426|reactome:R-HSA-5682113|reactome:R-HSA-8957275|reactome:R-HSA-8963888|reactome:R-HSA-8963896|reactome:R-HSA-8963901|reactome:R-HSA-8964011|reactome:R-HSA-8964058|reactome:R-HSA-9707616|reactome:R-HSA-975634|reactome:R-HSA-977225 - - - figure legend:Fig.2A,Supp Table S5|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-testis)|taxid:9606(Homo sapiens) - 2020/03/24 2021/11/30 rogid:ZE4tXTFi7lUCcIbCL4KHzY3a6xM9606 rogid:yEzPDeU8Uu/43dkLLOBAy6ey1vs9606 rigid:/AFat0DrynAJ5ofEnoPSTThlxCE false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9BY14 uniprotkb:Q02878 intact:EBI-12549378|ensembl:ENSP00000472769|uniprotkb:Q7L5R2|uniprotkb:Q9BPY7 intact:EBI-359655|uniprotkb:Q2M3Q3|uniprotkb:Q8WW97|ensembl:ENSP00000202773|ensembl:ENSP00000403172 psi-mi:tx101_human(display_long)|uniprotkb:TEX101(gene name)|psi-mi:TEX101(display_short)|uniprotkb:Cell surface receptor NYD-SP8(gene name synonym)|uniprotkb:SGRG(gene name synonym)|uniprotkb:Scleroderma-associated autoantigen(gene name synonym)|uniprotkb:Spermatogenesis-related gene protein(gene name synonym)|uniprotkb:UNQ867/PRO1884(orf name) psi-mi:rl6_human(display_long)|uniprotkb:RPL6(gene name)|psi-mi:RPL6(display_short)|uniprotkb:TXREB1(gene name synonym)|uniprotkb:Tax-responsive enhancer element-binding protein 107(gene name synonym)|uniprotkb:Neoplasm-related protein C140(gene name synonym)|uniprotkb:Large ribosomal subunit protein eL6(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Schiza et al. (2018) imex:IM-28077|pubmed:30097533 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-25505061|imex:IM-28077-3 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000131126(gene)|ensembl:ENST00000598265(transcript)|go:"GO:0001669"(acrosomal vesicle)|go:"GO:0002080"(acrosomal membrane)|go:"GO:0005576"(extracellular region)|go:"GO:0005886"(plasma membrane)|go:"GO:0007339"(binding of sperm to zona pellucida)|go:"GO:0009566"(fertilization)|go:"GO:0030317"(flagellated sperm motility)|go:"GO:0044853"(plasma membrane raft)|go:"GO:0046658"(anchored component of plasma membrane)|go:"GO:1901317"(regulation of flagellated sperm motility)|interpro:IPR016054(Ly-6 antigen / uPA receptor -like)|rcsb pdb:7BPR|reactome:R-HSA-163125|refseq:NP_001123483.1|refseq:NP_113639.4 refseq:NP_000961.2|refseq:NP_001019833.1|ensembl:ENSG00000089009(gene)|ensembl:ENST00000202773(transcript)|ensembl:ENST00000424576(transcript)|go:"GO:0000027"(ribosomal large subunit assembly)|go:"GO:0002181"(cytoplasmic translation)|go:"GO:0003677"(DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005634"(nucleus)|go:"GO:0005791"(rough endoplasmic reticulum)|go:"GO:0005829"(cytosol)|go:"GO:0005925"(focal adhesion)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006412"(translation)|go:"GO:0014069"(postsynaptic density)|go:"GO:0016020"(membrane)|go:"GO:0022625"(cytosolic large ribosomal subunit)|go:"GO:0022626"(cytosolic ribosome)|go:"GO:0036464"(cytoplasmic ribonucleoprotein granule)|go:"GO:0042788"(polysomal ribosome)|go:"GO:0045296"(cadherin binding)|interpro:IPR000915(Ribosomal protein L6E)|interpro:IPR005568(Ribosomal protein L6, N-terminal)|interpro:IPR008991(Translation protein SH3-like)|interpro:IPR014722(Translation protein SH3-like, subgroup)|interpro:IPR041997|mint:Q02878|rcsb pdb:4UG0|rcsb pdb:4V6X|rcsb pdb:5AJ0|rcsb pdb:5LKS|rcsb pdb:5T2C|rcsb pdb:6EK0|rcsb pdb:6IP5|rcsb pdb:6IP6|rcsb pdb:6IP8|rcsb pdb:6LQM|rcsb pdb:6LSR|rcsb pdb:6LSS|rcsb pdb:6LU8|rcsb pdb:6OLE|rcsb pdb:6OLF|rcsb pdb:6OLG|rcsb pdb:6OLI|rcsb pdb:6OLZ|rcsb pdb:6OM0|rcsb pdb:6OM7|rcsb pdb:6QZP|rcsb pdb:6W6L|rcsb pdb:6XA1|rcsb pdb:6Y0G|rcsb pdb:6Y2L|rcsb pdb:6Y57|rcsb pdb:6Y6X|rcsb pdb:6Z6L|rcsb pdb:6Z6M|rcsb pdb:6Z6N|rcsb pdb:6ZM7|rcsb pdb:6ZME|rcsb pdb:6ZMI|rcsb pdb:6ZMO|rcsb pdb:7BHP|reactome:R-HSA-156827|reactome:R-HSA-156902|reactome:R-HSA-1799339|reactome:R-HSA-192823|reactome:R-HSA-2408557|reactome:R-HSA-6791226|reactome:R-HSA-72689|reactome:R-HSA-72706|reactome:R-HSA-72764|reactome:R-HSA-9010553|reactome:R-HSA-9633012|reactome:R-HSA-975956|reactome:R-HSA-975957|refseq:NP_001307066.1|refseq:NP_001307067.1|refseq:NP_001307068.1|refseq:NP_001307069.1|refseq:NP_001307070.1|refseq:XP_016875270.1|refseq:XP_016875271.1|dip:DIP-27547N - - - figure legend:Fig.2A,Supp Table S5|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-testis)|taxid:9606(Homo sapiens) - 2020/03/24 2021/11/30 rogid:ZE4tXTFi7lUCcIbCL4KHzY3a6xM9606 rogid:Y7fx3ToInzucV2QmI8KLSdHxai09606 rigid:/AFat0DrynAJ5ofEnoPSTThlxCE false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9BY14 uniprotkb:P55083 intact:EBI-12549378|ensembl:ENSP00000472769|uniprotkb:Q7L5R2|uniprotkb:Q9BPY7 intact:EBI-2829794|uniprotkb:Q6P680|uniprotkb:A8KAJ1|uniprotkb:A8MVM2|uniprotkb:B4E317|ensembl:ENSP00000299610 psi-mi:tx101_human(display_long)|uniprotkb:TEX101(gene name)|psi-mi:TEX101(display_short)|uniprotkb:Cell surface receptor NYD-SP8(gene name synonym)|uniprotkb:SGRG(gene name synonym)|uniprotkb:Scleroderma-associated autoantigen(gene name synonym)|uniprotkb:Spermatogenesis-related gene protein(gene name synonym)|uniprotkb:UNQ867/PRO1884(orf name) psi-mi:mfap4_human(display_long)|uniprotkb:MFAP4(gene name)|psi-mi:MFAP4(display_short) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Schiza et al. (2018) imex:IM-28077|pubmed:30097533 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-25505061|imex:IM-28077-3 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000131126(gene)|ensembl:ENST00000598265(transcript)|go:"GO:0001669"(acrosomal vesicle)|go:"GO:0002080"(acrosomal membrane)|go:"GO:0005576"(extracellular region)|go:"GO:0005886"(plasma membrane)|go:"GO:0007339"(binding of sperm to zona pellucida)|go:"GO:0009566"(fertilization)|go:"GO:0030317"(flagellated sperm motility)|go:"GO:0044853"(plasma membrane raft)|go:"GO:0046658"(anchored component of plasma membrane)|go:"GO:1901317"(regulation of flagellated sperm motility)|interpro:IPR016054(Ly-6 antigen / uPA receptor -like)|rcsb pdb:7BPR|reactome:R-HSA-163125|refseq:NP_001123483.1|refseq:NP_113639.4 refseq:NP_001185624.1|refseq:NP_002395.1|ensembl:ENSG00000166482(gene)|ensembl:ENST00000299610(transcript)|go:"GO:0001527"(microfibril)|go:"GO:0001867"(complement activation, lectin pathway)|go:"GO:0003823"(antigen binding)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0007155"(cell adhesion)|go:"GO:0009650"(UV protection)|go:"GO:0010712"(regulation of collagen metabolic process)|go:"GO:0048251"(elastic fiber assembly)|go:"GO:0062023"(collagen-containing extracellular matrix)|go:"GO:0071493"(cellular response to UV-B)|go:"GO:0071953"(elastic fiber)|go:"GO:0097367"(carbohydrate derivative binding)|go:"GO:0097435"(supramolecular fiber organization)|interpro:IPR002181(Fibrinogen, alpha/beta/gamma chain, C-terminal globular)|interpro:IPR014716(Fibrinogen, alpha/beta/gamma chain, C-terminal globular, subdomain 1)|interpro:IPR036056|reactome:R-HSA-2129379 - - - figure legend:Fig.2A,Supp Table S5|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-testis)|taxid:9606(Homo sapiens) - 2020/03/24 2021/11/30 rogid:ZE4tXTFi7lUCcIbCL4KHzY3a6xM9606 rogid:pudRJmT0Rb32WgBHT7g7KZsSsME9606 rigid:/AFat0DrynAJ5ofEnoPSTThlxCE false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9BY14 uniprotkb:O14756 intact:EBI-12549378|ensembl:ENSP00000472769|uniprotkb:Q7L5R2|uniprotkb:Q9BPY7 intact:EBI-21599052|uniprotkb:O43275|ensembl:ENSP00000318631|ensembl:ENSP00000450698|ensembl:ENSP00000451406|ensembl:ENSP00000451753|ensembl:ENSP00000452273 psi-mi:tx101_human(display_long)|uniprotkb:TEX101(gene name)|psi-mi:TEX101(display_short)|uniprotkb:Cell surface receptor NYD-SP8(gene name synonym)|uniprotkb:SGRG(gene name synonym)|uniprotkb:Scleroderma-associated autoantigen(gene name synonym)|uniprotkb:Spermatogenesis-related gene protein(gene name synonym)|uniprotkb:UNQ867/PRO1884(orf name) psi-mi:h17b6_human(display_long)|uniprotkb:3-alpha->beta-hydroxysteroid epimerase(gene name synonym)|uniprotkb:Oxidative 3-alpha hydroxysteroid dehydrogenase(gene name synonym)|uniprotkb:Short chain dehydrogenase/reductase family 9C member 6(gene name synonym)|uniprotkb:HSD17B6(gene name)|psi-mi:HSD17B6(display_short)|uniprotkb:RODH(gene name synonym)|uniprotkb:SDR9C6(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Schiza et al. (2018) imex:IM-28077|pubmed:30097533 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-25505061|imex:IM-28077-3 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000131126(gene)|ensembl:ENST00000598265(transcript)|go:"GO:0001669"(acrosomal vesicle)|go:"GO:0002080"(acrosomal membrane)|go:"GO:0005576"(extracellular region)|go:"GO:0005886"(plasma membrane)|go:"GO:0007339"(binding of sperm to zona pellucida)|go:"GO:0009566"(fertilization)|go:"GO:0030317"(flagellated sperm motility)|go:"GO:0044853"(plasma membrane raft)|go:"GO:0046658"(anchored component of plasma membrane)|go:"GO:1901317"(regulation of flagellated sperm motility)|interpro:IPR016054(Ly-6 antigen / uPA receptor -like)|rcsb pdb:7BPR|reactome:R-HSA-163125|refseq:NP_001123483.1|refseq:NP_113639.4 refseq:NP_003716.2|refseq:XP_005269264.1|refseq:XP_005269265.1|refseq:XP_005269266.1|refseq:XP_006719735.1|refseq:XP_011537227.1|refseq:XP_011537228.1|refseq:XP_011537229.1|ensembl:ENSG00000025423(gene)|ensembl:ENST00000322165(transcript)|ensembl:ENST00000554150(transcript)|ensembl:ENST00000554643(transcript)|ensembl:ENST00000555159(transcript)|ensembl:ENST00000555805(transcript)|go:"GO:0003824"(catalytic activity)|go:"GO:0004745"(NAD-retinol dehydrogenase activity)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0006702"(androgen biosynthetic process)|go:"GO:0006710"(androgen catabolic process)|go:"GO:0009055"(electron transfer activity)|go:"GO:0016491"(oxidoreductase activity)|go:"GO:0031901"(early endosome membrane)|go:"GO:0044594"("17-beta-hydroxysteroid dehydrogenase (NAD+) activity")|go:"GO:0047023"(androsterone dehydrogenase activity)|go:"GO:0047024"(5alpha-androstane-3beta,17beta-diol dehydrogenase activity)|go:"GO:0047035"("testosterone dehydrogenase (NAD+) activity")|go:"GO:0047044"(androstan-3-alpha,17-beta-diol dehydrogenase activity)|go:"GO:0047045"("testosterone 17-beta-dehydrogenase (NADP+) activity")|go:"GO:0062175"(brexanolone catabolic process)|go:"GO:0072582"("17-beta-hydroxysteroid dehydrogenase (NADP+) activity")|interpro:IPR002347(Glucose/ribitol dehydrogenase)|interpro:IPR020904|interpro:IPR036291|reactome:R-HSA-2453902 - - - figure legend:Fig.2A,Supp Table S5|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-testis)|taxid:9606(Homo sapiens) - 2020/03/24 2021/11/30 rogid:ZE4tXTFi7lUCcIbCL4KHzY3a6xM9606 rogid:DcOlelhxAt7zSxwwYVxqmgck3X09606 rigid:/AFat0DrynAJ5ofEnoPSTThlxCE false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9BY14 uniprotkb:O75964 intact:EBI-12549378|ensembl:ENSP00000472769|uniprotkb:Q7L5R2|uniprotkb:Q9BPY7 intact:EBI-1044001|uniprotkb:Q96BV6|uniprotkb:Q9UBZ7|ensembl:ENSP00000300688|uniprotkb:A8K0K3 psi-mi:tx101_human(display_long)|uniprotkb:TEX101(gene name)|psi-mi:TEX101(display_short)|uniprotkb:Cell surface receptor NYD-SP8(gene name synonym)|uniprotkb:SGRG(gene name synonym)|uniprotkb:Scleroderma-associated autoantigen(gene name synonym)|uniprotkb:Spermatogenesis-related gene protein(gene name synonym)|uniprotkb:UNQ867/PRO1884(orf name) psi-mi:atp5l_human(display_long)|uniprotkb:ATP5MG(gene name)|psi-mi:ATP5MG(display_short)|uniprotkb:ATP synthase membrane subunit g(gene name synonym)|uniprotkb:ATP5L(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Schiza et al. (2018) imex:IM-28077|pubmed:30097533 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-25505061|imex:IM-28077-3 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000131126(gene)|ensembl:ENST00000598265(transcript)|go:"GO:0001669"(acrosomal vesicle)|go:"GO:0002080"(acrosomal membrane)|go:"GO:0005576"(extracellular region)|go:"GO:0005886"(plasma membrane)|go:"GO:0007339"(binding of sperm to zona pellucida)|go:"GO:0009566"(fertilization)|go:"GO:0030317"(flagellated sperm motility)|go:"GO:0044853"(plasma membrane raft)|go:"GO:0046658"(anchored component of plasma membrane)|go:"GO:1901317"(regulation of flagellated sperm motility)|interpro:IPR016054(Ly-6 antigen / uPA receptor -like)|rcsb pdb:7BPR|reactome:R-HSA-163125|refseq:NP_001123483.1|refseq:NP_113639.4 refseq:NP_006467.4|ensembl:ENSG00000167283(gene)|ensembl:ENST00000300688(transcript)|go:"GO:0000276"("mitochondrial proton-transporting ATP synthase complex, coupling factor F(o)")|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005753"(mitochondrial proton-transporting ATP synthase complex)|go:"GO:0015078"(proton transmembrane transporter activity)|go:"GO:0015986"(ATP synthesis coupled proton transport)|go:"GO:0042776"(mitochondrial ATP synthesis coupled proton transport)|interpro:IPR006808(ATPase, F0 complex, subunit G, mitochondrial)|interpro:IPR016702(Mitochondrial ATP synthase subunit g, animal)|mint:O75964|reactome:R-HSA-163210|reactome:R-HSA-8949613 - - - figure legend:Fig.2A,Supp Table S5|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-testis)|taxid:9606(Homo sapiens) - 2020/03/24 2021/11/30 rogid:ZE4tXTFi7lUCcIbCL4KHzY3a6xM9606 rogid:mn5/fFqk4xCCHb/MEuLAi5/lqmI9606 rigid:/AFat0DrynAJ5ofEnoPSTThlxCE false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9BY14 uniprotkb:Q16563 intact:EBI-12549378|ensembl:ENSP00000472769|uniprotkb:Q7L5R2|uniprotkb:Q9BPY7 intact:EBI-2800683|uniprotkb:A4D0R2|uniprotkb:Q96AR8|ensembl:ENSP00000011473 psi-mi:tx101_human(display_long)|uniprotkb:TEX101(gene name)|psi-mi:TEX101(display_short)|uniprotkb:Cell surface receptor NYD-SP8(gene name synonym)|uniprotkb:SGRG(gene name synonym)|uniprotkb:Scleroderma-associated autoantigen(gene name synonym)|uniprotkb:Spermatogenesis-related gene protein(gene name synonym)|uniprotkb:UNQ867/PRO1884(orf name) psi-mi:sypl1_human(display_long)|uniprotkb:SYPL(gene name synonym)|uniprotkb:Pantophysin(gene name synonym)|uniprotkb:SYPL1(gene name)|psi-mi:SYPL1(display_short) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Schiza et al. (2018) imex:IM-28077|pubmed:30097533 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-25505061|imex:IM-28077-3 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000131126(gene)|ensembl:ENST00000598265(transcript)|go:"GO:0001669"(acrosomal vesicle)|go:"GO:0002080"(acrosomal membrane)|go:"GO:0005576"(extracellular region)|go:"GO:0005886"(plasma membrane)|go:"GO:0007339"(binding of sperm to zona pellucida)|go:"GO:0009566"(fertilization)|go:"GO:0030317"(flagellated sperm motility)|go:"GO:0044853"(plasma membrane raft)|go:"GO:0046658"(anchored component of plasma membrane)|go:"GO:1901317"(regulation of flagellated sperm motility)|interpro:IPR016054(Ly-6 antigen / uPA receptor -like)|rcsb pdb:7BPR|reactome:R-HSA-163125|refseq:NP_001123483.1|refseq:NP_113639.4 refseq:NP_006745.1|refseq:NP_874384.1|ensembl:ENSG00000008282(gene)|ensembl:ENST00000011473(transcript)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0007268"(chemical synaptic transmission)|go:"GO:0016021"(integral component of membrane)|go:"GO:0017075"(syntaxin-1 binding)|go:"GO:0030141"(secretory granule)|go:"GO:0030285"(integral component of synaptic vesicle membrane)|go:"GO:0030672"(synaptic vesicle membrane)|go:"GO:0042470"(melanosome)|go:"GO:0070062"(extracellular exosome)|interpro:IPR001285(Synaptophysin/synaptoporin)|interpro:IPR008253(Marvel) - - - figure legend:Fig.2A,Supp Table S5|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-testis)|taxid:9606(Homo sapiens) - 2020/03/24 2021/11/30 rogid:ZE4tXTFi7lUCcIbCL4KHzY3a6xM9606 rogid:kw4EuKqd6PhotpKiicCjB99ZZCY9606 rigid:/AFat0DrynAJ5ofEnoPSTThlxCE false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9BY14 uniprotkb:P56134 intact:EBI-12549378|ensembl:ENSP00000472769|uniprotkb:Q7L5R2|uniprotkb:Q9BPY7 intact:EBI-712794|ensembl:ENSP00000292475|uniprotkb:O76079|uniprotkb:Q96L83|uniprotkb:Q9BTI8|uniprotkb:C9J8H9|uniprotkb:F8W7V3|intact:EBI-11047094|uniprotkb:Q6IBB3 psi-mi:tx101_human(display_long)|uniprotkb:TEX101(gene name)|psi-mi:TEX101(display_short)|uniprotkb:Cell surface receptor NYD-SP8(gene name synonym)|uniprotkb:SGRG(gene name synonym)|uniprotkb:Scleroderma-associated autoantigen(gene name synonym)|uniprotkb:Spermatogenesis-related gene protein(gene name synonym)|uniprotkb:UNQ867/PRO1884(orf name) psi-mi:atpk_human(display_long)|uniprotkb:ATP5MF(gene name)|psi-mi:ATP5MF(display_short)|uniprotkb:ATP synthase membrane subunit f(gene name synonym)|uniprotkb:ATP5J2(gene name synonym)|uniprotkb:ATP5JL(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Schiza et al. (2018) imex:IM-28077|pubmed:30097533 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-25505061|imex:IM-28077-3 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000131126(gene)|ensembl:ENST00000598265(transcript)|go:"GO:0001669"(acrosomal vesicle)|go:"GO:0002080"(acrosomal membrane)|go:"GO:0005576"(extracellular region)|go:"GO:0005886"(plasma membrane)|go:"GO:0007339"(binding of sperm to zona pellucida)|go:"GO:0009566"(fertilization)|go:"GO:0030317"(flagellated sperm motility)|go:"GO:0044853"(plasma membrane raft)|go:"GO:0046658"(anchored component of plasma membrane)|go:"GO:1901317"(regulation of flagellated sperm motility)|interpro:IPR016054(Ly-6 antigen / uPA receptor -like)|rcsb pdb:7BPR|reactome:R-HSA-163125|refseq:NP_001123483.1|refseq:NP_113639.4 ensembl:ENSG00000241468(gene)|ensembl:ENST00000292475(transcript)|go:"GO:0000276"("mitochondrial proton-transporting ATP synthase complex, coupling factor F(o)")|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005753"(mitochondrial proton-transporting ATP synthase complex)|go:"GO:0016021"(integral component of membrane)|go:"GO:0031965"(nuclear membrane)|go:"GO:0042776"(mitochondrial ATP synthesis coupled proton transport)|go:"GO:1902600"(proton transmembrane transport)|interpro:IPR019344|mint:P56134|reactome:R-HSA-163210|reactome:R-HSA-8949613|refseq:NP_001003713.1|refseq:NP_004880.1|refseq:NP_001003714.1|refseq:NP_001034267.1 - - - figure legend:Fig.2A,Supp Table S5|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-testis)|taxid:9606(Homo sapiens) - 2020/03/24 2021/11/30 rogid:ZE4tXTFi7lUCcIbCL4KHzY3a6xM9606 rogid:+WS7rjFef6JE+mlZ4Q8TF2A+G0E9606 rigid:/AFat0DrynAJ5ofEnoPSTThlxCE false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9BY14 uniprotkb:O15173 intact:EBI-12549378|ensembl:ENSP00000472769|uniprotkb:Q7L5R2|uniprotkb:Q9BPY7 intact:EBI-1050125|uniprotkb:Q569H1|ensembl:ENSP00000296425|ensembl:ENSP00000429301 psi-mi:tx101_human(display_long)|uniprotkb:TEX101(gene name)|psi-mi:TEX101(display_short)|uniprotkb:Cell surface receptor NYD-SP8(gene name synonym)|uniprotkb:SGRG(gene name synonym)|uniprotkb:Scleroderma-associated autoantigen(gene name synonym)|uniprotkb:Spermatogenesis-related gene protein(gene name synonym)|uniprotkb:UNQ867/PRO1884(orf name) psi-mi:pgrc2_human(display_long)|uniprotkb:Progesterone membrane-binding protein(gene name synonym)|uniprotkb:Steroid receptor protein DG6(gene name synonym)|uniprotkb:PGRMC2(gene name)|psi-mi:PGRMC2(display_short)|uniprotkb:DG6(gene name synonym)|uniprotkb:PMBP(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Schiza et al. (2018) imex:IM-28077|pubmed:30097533 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-25505061|imex:IM-28077-3 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000131126(gene)|ensembl:ENST00000598265(transcript)|go:"GO:0001669"(acrosomal vesicle)|go:"GO:0002080"(acrosomal membrane)|go:"GO:0005576"(extracellular region)|go:"GO:0005886"(plasma membrane)|go:"GO:0007339"(binding of sperm to zona pellucida)|go:"GO:0009566"(fertilization)|go:"GO:0030317"(flagellated sperm motility)|go:"GO:0044853"(plasma membrane raft)|go:"GO:0046658"(anchored component of plasma membrane)|go:"GO:1901317"(regulation of flagellated sperm motility)|interpro:IPR016054(Ly-6 antigen / uPA receptor -like)|rcsb pdb:7BPR|reactome:R-HSA-163125|refseq:NP_001123483.1|refseq:NP_113639.4 refseq:NP_006311.2|ensembl:ENSG00000164040(gene)|ensembl:ENST00000296425(transcript)|ensembl:ENST00000520121(transcript)|go:"GO:0003707"(steroid hormone receptor activity)|go:"GO:0005496"(steroid binding)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0012505"(endomembrane system)|go:"GO:0015232"(heme transmembrane transporter activity)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0020037"(heme binding)|go:"GO:0060612"(adipose tissue development)|interpro:IPR001199(Cytochrome b5)|interpro:IPR036400|mint:O15173|reactome:R-HSA-8980692|reactome:R-HSA-9013404|reactome:R-HSA-9013405|reactome:R-HSA-9013408|reactome:R-HSA-9013423 - - - figure legend:Fig.2A,Supp Table S5|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-testis)|taxid:9606(Homo sapiens) - 2020/03/24 2021/11/30 rogid:ZE4tXTFi7lUCcIbCL4KHzY3a6xM9606 rogid:y8PU98eUcxnJLxobBcFL40xaprw9606 rigid:/AFat0DrynAJ5ofEnoPSTThlxCE false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9BY14 uniprotkb:P23786 intact:EBI-12549378|ensembl:ENSP00000472769|uniprotkb:Q7L5R2|uniprotkb:Q9BPY7 intact:EBI-6269566|ensembl:ENSP00000360541|uniprotkb:B2R6S0|uniprotkb:Q5SW68|uniprotkb:Q9BQ26 psi-mi:tx101_human(display_long)|uniprotkb:TEX101(gene name)|psi-mi:TEX101(display_short)|uniprotkb:Cell surface receptor NYD-SP8(gene name synonym)|uniprotkb:SGRG(gene name synonym)|uniprotkb:Scleroderma-associated autoantigen(gene name synonym)|uniprotkb:Spermatogenesis-related gene protein(gene name synonym)|uniprotkb:UNQ867/PRO1884(orf name) psi-mi:cpt2_human(display_long)|uniprotkb:CPT2(gene name)|psi-mi:CPT2(display_short)|uniprotkb:CPT1(gene name synonym)|uniprotkb:Carnitine palmitoyltransferase II(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Schiza et al. (2018) imex:IM-28077|pubmed:30097533 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-25505061|imex:IM-28077-3 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000131126(gene)|ensembl:ENST00000598265(transcript)|go:"GO:0001669"(acrosomal vesicle)|go:"GO:0002080"(acrosomal membrane)|go:"GO:0005576"(extracellular region)|go:"GO:0005886"(plasma membrane)|go:"GO:0007339"(binding of sperm to zona pellucida)|go:"GO:0009566"(fertilization)|go:"GO:0030317"(flagellated sperm motility)|go:"GO:0044853"(plasma membrane raft)|go:"GO:0046658"(anchored component of plasma membrane)|go:"GO:1901317"(regulation of flagellated sperm motility)|interpro:IPR016054(Ly-6 antigen / uPA receptor -like)|rcsb pdb:7BPR|reactome:R-HSA-163125|refseq:NP_001123483.1|refseq:NP_113639.4 ensembl:ENSG00000157184(gene)|ensembl:ENST00000371486(transcript)|go:"GO:0001676"(long-chain fatty acid metabolic process)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0006635"(fatty acid beta-oxidation)|go:"GO:0006853"(carnitine shuttle)|go:"GO:0008458"(carnitine O-octanoyltransferase activity)|go:"GO:0009437"(carnitine metabolic process)|go:"GO:0016746"(acyltransferase activity)|go:"GO:0120162"(positive regulation of cold-induced thermogenesis)|interpro:IPR000542(Acyltransferase ChoActase/COT/CPT)|interpro:IPR023213|interpro:IPR039551|interpro:IPR042572|reactome:R-HSA-1989781|reactome:R-HSA-200425|go:"GO:0004095"(carnitine O-palmitoyltransferase activity)|refseq:NP_000089.1 - - - figure legend:Fig.2A,Supp Table S5|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-testis)|taxid:9606(Homo sapiens) - 2020/03/24 2021/11/30 rogid:ZE4tXTFi7lUCcIbCL4KHzY3a6xM9606 rogid:maFH51Fz1PYXUzBwLPr3sGlVkcY9606 rigid:/AFat0DrynAJ5ofEnoPSTThlxCE false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9BY14 uniprotkb:P09972 intact:EBI-12549378|ensembl:ENSP00000472769|uniprotkb:Q7L5R2|uniprotkb:Q9BPY7 intact:EBI-2952751|ensembl:ENSP00000226253|ensembl:ENSP00000378731|uniprotkb:Q6P0L5|uniprotkb:Q3SYL3|uniprotkb:Q6FH94|uniprotkb:B2R5R3 psi-mi:tx101_human(display_long)|uniprotkb:TEX101(gene name)|psi-mi:TEX101(display_short)|uniprotkb:Cell surface receptor NYD-SP8(gene name synonym)|uniprotkb:SGRG(gene name synonym)|uniprotkb:Scleroderma-associated autoantigen(gene name synonym)|uniprotkb:Spermatogenesis-related gene protein(gene name synonym)|uniprotkb:UNQ867/PRO1884(orf name) psi-mi:aldoc_human(display_long)|uniprotkb:ALDOC(gene name)|psi-mi:ALDOC(display_short)|uniprotkb:ALDC(gene name synonym)|uniprotkb:Brain-type aldolase(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Schiza et al. (2018) imex:IM-28077|pubmed:30097533 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-25505061|imex:IM-28077-3 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000131126(gene)|ensembl:ENST00000598265(transcript)|go:"GO:0001669"(acrosomal vesicle)|go:"GO:0002080"(acrosomal membrane)|go:"GO:0005576"(extracellular region)|go:"GO:0005886"(plasma membrane)|go:"GO:0007339"(binding of sperm to zona pellucida)|go:"GO:0009566"(fertilization)|go:"GO:0030317"(flagellated sperm motility)|go:"GO:0044853"(plasma membrane raft)|go:"GO:0046658"(anchored component of plasma membrane)|go:"GO:1901317"(regulation of flagellated sperm motility)|interpro:IPR016054(Ly-6 antigen / uPA receptor -like)|rcsb pdb:7BPR|reactome:R-HSA-163125|refseq:NP_001123483.1|refseq:NP_113639.4 interpro:IPR000741(Fructose-bisphosphate aldolase, class-I)|interpro:IPR013785(Aldolase-type TIM barrel)|interpro:IPR029768|mint:P09972|rcsb pdb:1XFB|reactome:R-HSA-6798695|reactome:R-HSA-70171|reactome:R-HSA-70263|ensembl:ENSG00000109107(gene)|ensembl:ENST00000226253(transcript)|ensembl:ENST00000395321(transcript)|go:"GO:0004332"(fructose-bisphosphate aldolase activity)|go:"GO:0005576"(extracellular region)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0006000"(fructose metabolic process)|go:"GO:0006096"(glycolytic process)|go:"GO:0008092"(cytoskeletal protein binding)|go:"GO:0030388"(fructose 1,6-bisphosphate metabolic process)|go:"GO:0030855"(epithelial cell differentiation)|go:"GO:0034774"(secretory granule lumen)|go:"GO:0070062"(extracellular exosome)|go:"GO:1904724"(tertiary granule lumen)|go:"GO:1904813"(ficolin-1-rich granule lumen)|refseq:NP_005156.1|refseq:XP_011522858.1|refseq:XP_005258006.1 - - - figure legend:Fig.2A,Supp Table S5|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-testis)|taxid:9606(Homo sapiens) - 2020/03/24 2021/11/30 rogid:ZE4tXTFi7lUCcIbCL4KHzY3a6xM9606 rogid:0ZRiaxKG2+jvyJw6MHu1cWGFEhk9606 rigid:/AFat0DrynAJ5ofEnoPSTThlxCE false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9BY14 uniprotkb:O75396 intact:EBI-12549378|ensembl:ENSP00000472769|uniprotkb:Q7L5R2|uniprotkb:Q9BPY7 intact:EBI-1058865|ensembl:ENSP00000463393|uniprotkb:A8K1G0 psi-mi:tx101_human(display_long)|uniprotkb:TEX101(gene name)|psi-mi:TEX101(display_short)|uniprotkb:Cell surface receptor NYD-SP8(gene name synonym)|uniprotkb:SGRG(gene name synonym)|uniprotkb:Scleroderma-associated autoantigen(gene name synonym)|uniprotkb:Spermatogenesis-related gene protein(gene name synonym)|uniprotkb:UNQ867/PRO1884(orf name) psi-mi:sc22b_human(display_long)|uniprotkb:SEC22B(gene name)|psi-mi:SEC22B(display_short)|uniprotkb:SEC22L1(gene name synonym)|uniprotkb:SEC22 vesicle-trafficking protein homolog B(gene name synonym)|uniprotkb:SEC22 vesicle-trafficking protein-like 1(gene name synonym)|uniprotkb:ER-Golgi SNARE of 24 kDa(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Schiza et al. (2018) imex:IM-28077|pubmed:30097533 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-25505061|imex:IM-28077-3 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000131126(gene)|ensembl:ENST00000598265(transcript)|go:"GO:0001669"(acrosomal vesicle)|go:"GO:0002080"(acrosomal membrane)|go:"GO:0005576"(extracellular region)|go:"GO:0005886"(plasma membrane)|go:"GO:0007339"(binding of sperm to zona pellucida)|go:"GO:0009566"(fertilization)|go:"GO:0030317"(flagellated sperm motility)|go:"GO:0044853"(plasma membrane raft)|go:"GO:0046658"(anchored component of plasma membrane)|go:"GO:1901317"(regulation of flagellated sperm motility)|interpro:IPR016054(Ly-6 antigen / uPA receptor -like)|rcsb pdb:7BPR|reactome:R-HSA-163125|refseq:NP_001123483.1|refseq:NP_113639.4 ensembl:ENSG00000265808(gene)|ensembl:ENST00000578049(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0005484"(SNAP receptor activity)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005793"(endoplasmic reticulum-Golgi intermediate compartment)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0006890"(retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0012507"(ER to Golgi transport vesicle membrane)|go:"GO:0015031"(protein transport)|go:"GO:0016021"(integral component of membrane)|go:"GO:0019905"(syntaxin binding)|go:"GO:0030133"(transport vesicle)|go:"GO:0030137"(COPI-coated vesicle)|go:"GO:0030670"(phagocytic vesicle membrane)|go:"GO:0031201"(SNARE complex)|go:"GO:0033116"(endoplasmic reticulum-Golgi intermediate compartment membrane)|go:"GO:0042470"(melanosome)|go:"GO:0045732"(positive regulation of protein catabolic process)|go:"GO:0048280"(vesicle fusion with Golgi apparatus)|go:"GO:1902902"(negative regulation of autophagosome assembly)|interpro:IPR001388(Synaptobrevin)|interpro:IPR010908(Longin)|interpro:IPR011012(Longin-like)|interpro:IPR042855|interpro:IPR044565|mint:O75396|rcsb pdb:2NUP|rcsb pdb:2NUT|rcsb pdb:3EGD|rcsb pdb:3EGX|refseq:NP_004883.3|reactome:R-HSA-204005|reactome:R-HSA-5694530|reactome:R-HSA-6811434|reactome:R-HSA-1236974|dip:DIP-50458N - - - figure legend:Fig.2A,Supp Table S5|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-testis)|taxid:9606(Homo sapiens) - 2020/03/24 2021/11/30 rogid:ZE4tXTFi7lUCcIbCL4KHzY3a6xM9606 rogid:DRKtD169T9eYZ2kFufLapidvcKs9606 rigid:/AFat0DrynAJ5ofEnoPSTThlxCE false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9BY14 uniprotkb:O75083 intact:EBI-12549378|ensembl:ENSP00000472769|uniprotkb:Q7L5R2|uniprotkb:Q9BPY7 intact:EBI-351917|uniprotkb:O75313|uniprotkb:Q8N6E5|uniprotkb:Q9UG05|uniprotkb:Q9UG78|uniprotkb:A8MPU4|uniprotkb:Q9UQE0|uniprotkb:A8K6E9|ensembl:ENSP00000371890|ensembl:ENSP00000427687 psi-mi:tx101_human(display_long)|uniprotkb:TEX101(gene name)|psi-mi:TEX101(display_short)|uniprotkb:Cell surface receptor NYD-SP8(gene name synonym)|uniprotkb:SGRG(gene name synonym)|uniprotkb:Scleroderma-associated autoantigen(gene name synonym)|uniprotkb:Spermatogenesis-related gene protein(gene name synonym)|uniprotkb:UNQ867/PRO1884(orf name) psi-mi:wdr1_human(display_long)|uniprotkb:WDR1(gene name)|psi-mi:WDR1(display_short)|uniprotkb:Actin-interacting protein 1(gene name synonym)|uniprotkb:NORI-1(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Schiza et al. (2018) imex:IM-28077|pubmed:30097533 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-25505061|imex:IM-28077-3 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000131126(gene)|ensembl:ENST00000598265(transcript)|go:"GO:0001669"(acrosomal vesicle)|go:"GO:0002080"(acrosomal membrane)|go:"GO:0005576"(extracellular region)|go:"GO:0005886"(plasma membrane)|go:"GO:0007339"(binding of sperm to zona pellucida)|go:"GO:0009566"(fertilization)|go:"GO:0030317"(flagellated sperm motility)|go:"GO:0044853"(plasma membrane raft)|go:"GO:0046658"(anchored component of plasma membrane)|go:"GO:1901317"(regulation of flagellated sperm motility)|interpro:IPR016054(Ly-6 antigen / uPA receptor -like)|rcsb pdb:7BPR|reactome:R-HSA-163125|refseq:NP_001123483.1|refseq:NP_113639.4 refseq:NP_005103.2|refseq:NP_059830.1|ensembl:ENSG00000071127(gene)|ensembl:ENST00000382452(transcript)|ensembl:ENST00000499869(transcript)|go:"GO:0002102"(podosome)|go:"GO:0002446"(neutrophil mediated immunity)|go:"GO:0005576"(extracellular region)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0007605"(sensory perception of sound)|go:"GO:0008360"(regulation of cell shape)|go:"GO:0030042"(actin filament depolymerization)|go:"GO:0030043"(actin filament fragmentation)|go:"GO:0030054"(cell junction)|go:"GO:0030220"(platelet formation)|go:"GO:0030834"(regulation of actin filament depolymerization)|go:"GO:0030836"(positive regulation of actin filament depolymerization)|go:"GO:0030864"(cortical actin cytoskeleton)|go:"GO:0030865"(cortical cytoskeleton organization)|go:"GO:0040011"(locomotion)|go:"GO:0042247"(establishment of planar polarity of follicular epithelium)|go:"GO:0042995"(cell projection)|go:"GO:0043297"(apical junction assembly)|go:"GO:0045199"(maintenance of epithelial cell apical/basal polarity)|go:"GO:0045214"(sarcomere organization)|go:"GO:0048713"(regulation of oligodendrocyte differentiation)|go:"GO:0051015"(actin filament binding)|go:"GO:0060307"(regulation of ventricular cardiac muscle cell membrane repolarization)|go:"GO:0070062"(extracellular exosome)|go:"GO:1990266"(neutrophil migration)|interpro:IPR001680(WD40 repeat)|interpro:IPR011045(Nitrous oxide reductase, N-terminal)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019775|interpro:IPR020472|interpro:IPR036322|mint:O75083|reactome:R-HSA-114608 - - - figure legend:Fig.2A,Supp Table S5|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-testis)|taxid:9606(Homo sapiens) - 2020/03/24 2021/11/30 rogid:ZE4tXTFi7lUCcIbCL4KHzY3a6xM9606 rogid:ewKq6uA2Wrg/uK31ayOoenA9Gv49606 rigid:/AFat0DrynAJ5ofEnoPSTThlxCE false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9BY14 uniprotkb:Q9UJZ1 intact:EBI-12549378|ensembl:ENSP00000472769|uniprotkb:Q7L5R2|uniprotkb:Q9BPY7 intact:EBI-1044428|ensembl:ENSP00000348886|uniprotkb:O60376|uniprotkb:Q53G29|uniprotkb:Q96FY2|uniprotkb:Q9P042|uniprotkb:D3DRN3|uniprotkb:B4E1K7 psi-mi:tx101_human(display_long)|uniprotkb:TEX101(gene name)|psi-mi:TEX101(display_short)|uniprotkb:Cell surface receptor NYD-SP8(gene name synonym)|uniprotkb:SGRG(gene name synonym)|uniprotkb:Scleroderma-associated autoantigen(gene name synonym)|uniprotkb:Spermatogenesis-related gene protein(gene name synonym)|uniprotkb:UNQ867/PRO1884(orf name) psi-mi:stml2_human(display_long)|uniprotkb:EPB72-like protein 2(gene name synonym)|uniprotkb:STOML2(gene name)|psi-mi:STOML2(display_short)|uniprotkb:SLP2(gene name synonym)|uniprotkb:HSPC108(orf name)|uniprotkb:Paraprotein target 7(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Schiza et al. (2018) imex:IM-28077|pubmed:30097533 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-25505061|imex:IM-28077-3 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000131126(gene)|ensembl:ENST00000598265(transcript)|go:"GO:0001669"(acrosomal vesicle)|go:"GO:0002080"(acrosomal membrane)|go:"GO:0005576"(extracellular region)|go:"GO:0005886"(plasma membrane)|go:"GO:0007339"(binding of sperm to zona pellucida)|go:"GO:0009566"(fertilization)|go:"GO:0030317"(flagellated sperm motility)|go:"GO:0044853"(plasma membrane raft)|go:"GO:0046658"(anchored component of plasma membrane)|go:"GO:1901317"(regulation of flagellated sperm motility)|interpro:IPR016054(Ly-6 antigen / uPA receptor -like)|rcsb pdb:7BPR|reactome:R-HSA-163125|refseq:NP_001123483.1|refseq:NP_113639.4 ensembl:ENSG00000165283(gene)|ensembl:ENST00000356493(transcript)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005758"(mitochondrial intermembrane space)|go:"GO:0005856"(cytoskeleton)|go:"GO:0006851"(mitochondrial calcium ion transmembrane transport)|go:"GO:0007005"(mitochondrion organization)|go:"GO:0010876"(lipid localization)|go:"GO:0010918"(positive regulation of mitochondrial membrane potential)|go:"GO:0019897"(extrinsic component of plasma membrane)|go:"GO:0032743"(positive regulation of interleukin-2 production)|go:"GO:0034982"(mitochondrial protein processing)|go:"GO:0006874"(cellular calcium ion homeostasis)|go:"GO:0035710"(CD4-positive, alpha-beta T cell activation)|go:"GO:0042776"(mitochondrial ATP synthesis coupled proton transport)|go:"GO:0045121"(membrane raft)|go:"GO:0050852"(T cell receptor signaling pathway)|go:"GO:0051020"(GTPase binding)|go:"GO:0051259"(protein complex oligomerization)|go:"GO:0090297"(positive regulation of mitochondrial DNA replication)|go:"GO:1900210"(positive regulation of cardiolipin metabolic process)|go:"GO:1901612"(cardiolipin binding)|go:"GO:1990046"(stress-induced mitochondrial fusion)|interpro:IPR001107(Band 7 protein)|interpro:IPR001972(Stomatin)|interpro:IPR032435|interpro:IPR036013|mint:Q9UJZ1|reactome:R-HSA-8949664|refseq:NP_001273960.1|refseq:NP_038470.1|refseq:NP_001273961.1 - - - figure legend:Fig.2A,Supp Table S5|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-testis)|taxid:9606(Homo sapiens) - 2020/03/24 2021/11/30 rogid:ZE4tXTFi7lUCcIbCL4KHzY3a6xM9606 rogid:VH6uT4ShPg3IpPHbQtaSVXjZAYg9606 rigid:/AFat0DrynAJ5ofEnoPSTThlxCE false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9BY14 uniprotkb:Q06278 intact:EBI-12549378|ensembl:ENSP00000472769|uniprotkb:Q7L5R2|uniprotkb:Q9BPY7 intact:EBI-3926368|uniprotkb:Q9BYF0|uniprotkb:O14765|uniprotkb:Q9UPG6|uniprotkb:Q53TV3|uniprotkb:Q53RR8|ensembl:ENSP00000363832 psi-mi:tx101_human(display_long)|uniprotkb:TEX101(gene name)|psi-mi:TEX101(display_short)|uniprotkb:Cell surface receptor NYD-SP8(gene name synonym)|uniprotkb:SGRG(gene name synonym)|uniprotkb:Scleroderma-associated autoantigen(gene name synonym)|uniprotkb:Spermatogenesis-related gene protein(gene name synonym)|uniprotkb:UNQ867/PRO1884(orf name) psi-mi:aoxa_human(display_long)|uniprotkb:Aldehyde oxidase 1(gene name synonym)|uniprotkb:Azaheterocycle hydroxylase(gene name synonym)|uniprotkb:AOX1(gene name)|psi-mi:AOX1(display_short)|uniprotkb:AO(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Schiza et al. (2018) imex:IM-28077|pubmed:30097533 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-25505061|imex:IM-28077-3 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000131126(gene)|ensembl:ENST00000598265(transcript)|go:"GO:0001669"(acrosomal vesicle)|go:"GO:0002080"(acrosomal membrane)|go:"GO:0005576"(extracellular region)|go:"GO:0005886"(plasma membrane)|go:"GO:0007339"(binding of sperm to zona pellucida)|go:"GO:0009566"(fertilization)|go:"GO:0030317"(flagellated sperm motility)|go:"GO:0044853"(plasma membrane raft)|go:"GO:0046658"(anchored component of plasma membrane)|go:"GO:1901317"(regulation of flagellated sperm motility)|interpro:IPR016054(Ly-6 antigen / uPA receptor -like)|rcsb pdb:7BPR|reactome:R-HSA-163125|refseq:NP_001123483.1|refseq:NP_113639.4 refseq:NP_001150.3|ensembl:ENSG00000138356(gene)|ensembl:ENST00000374700(transcript)|go:"GO:0004031"(aldehyde oxidase activity)|go:"GO:0005506"(iron ion binding)|go:"GO:0005829"(cytosol)|go:"GO:0016491"(oxidoreductase activity)|go:"GO:0017144"|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043546"(molybdopterin cofactor binding)|go:"GO:0050660"(flavin adenine dinucleotide binding)|go:"GO:0051287"(NAD binding)|go:"GO:0051537"(2 iron, 2 sulfur cluster binding)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071949"(FAD binding)|go:"GO:0102797"("geranial:oxygen oxidoreductase activity")|go:"GO:0102798"("heptaldehyde:oxygen oxidoreductase activity")|interpro:IPR000674(Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead)|interpro:IPR001041(Ferredoxin)|interpro:IPR002346(Molybdopterin dehydrogenase, FAD-binding)|interpro:IPR002888([2Fe-2S]-binding)|interpro:IPR005107(CO dehydrogenase flavoprotein, C-terminal)|interpro:IPR006058(2Fe-2S ferredoxin, iron-sulphur binding site)|interpro:IPR008274(Aldehyde oxidase and xanthine dehydrogenase, molybdopterin binding)|interpro:IPR012675(Beta-grasp fold, ferredoxin-type)|interpro:IPR014313(Aldehyde oxidase)|interpro:IPR016166(FAD-binding, type 2)|interpro:IPR016167(FAD-binding, type 2, subdomain 1)|interpro:IPR037165|rcsb pdb:4UHW|rcsb pdb:4UHX|rcsb pdb:5EPG|rcsb pdb:6Q6Q|reactome:R-HSA-964975|interpro:IPR016169(CO dehydrogenase flavoprotein-like, FAD-binding, subdomain 2)|interpro:IPR016208(Aldehyde oxidase/xanthine dehydrogenase)|interpro:IPR022407|interpro:IPR036010|interpro:IPR036318|interpro:IPR036683|interpro:IPR036856|interpro:IPR036884|dip:DIP-61698N - - - figure legend:Fig.2A,Supp Table S5|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-testis)|taxid:9606(Homo sapiens) - 2020/03/24 2021/11/30 rogid:ZE4tXTFi7lUCcIbCL4KHzY3a6xM9606 rogid:WKBp5ZU9waYrMd19PjPX/sc1Wmk9606 rigid:/AFat0DrynAJ5ofEnoPSTThlxCE false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9BY14 uniprotkb:P00390 intact:EBI-12549378|ensembl:ENSP00000472769|uniprotkb:Q7L5R2|uniprotkb:Q9BPY7 intact:EBI-720325|uniprotkb:C8KIM0|uniprotkb:C8KIL8|uniprotkb:C8KIL9|ensembl:ENSP00000221130|uniprotkb:Q7Z5C9|uniprotkb:Q9NP63|uniprotkb:D3DSV3 psi-mi:tx101_human(display_long)|uniprotkb:TEX101(gene name)|psi-mi:TEX101(display_short)|uniprotkb:Cell surface receptor NYD-SP8(gene name synonym)|uniprotkb:SGRG(gene name synonym)|uniprotkb:Scleroderma-associated autoantigen(gene name synonym)|uniprotkb:Spermatogenesis-related gene protein(gene name synonym)|uniprotkb:UNQ867/PRO1884(orf name) psi-mi:gshr_human(display_long)|uniprotkb:GLUR(gene name synonym)|uniprotkb:GRD1(gene name synonym)|uniprotkb:GSR(gene name)|psi-mi:GSR(display_short) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Schiza et al. (2018) imex:IM-28077|pubmed:30097533 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-25505061|imex:IM-28077-3 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000131126(gene)|ensembl:ENST00000598265(transcript)|go:"GO:0001669"(acrosomal vesicle)|go:"GO:0002080"(acrosomal membrane)|go:"GO:0005576"(extracellular region)|go:"GO:0005886"(plasma membrane)|go:"GO:0007339"(binding of sperm to zona pellucida)|go:"GO:0009566"(fertilization)|go:"GO:0030317"(flagellated sperm motility)|go:"GO:0044853"(plasma membrane raft)|go:"GO:0046658"(anchored component of plasma membrane)|go:"GO:1901317"(regulation of flagellated sperm motility)|interpro:IPR016054(Ly-6 antigen / uPA receptor -like)|rcsb pdb:7BPR|reactome:R-HSA-163125|refseq:NP_001123483.1|refseq:NP_113639.4 ensembl:ENSG00000104687(gene)|ensembl:ENST00000221130(transcript)|go:"GO:0004362"("glutathione-disulfide reductase (NADPH) activity")|go:"GO:0005739"(mitochondrion)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0005829"(cytosol)|go:"GO:0006749"(glutathione metabolic process)|go:"GO:0009055"(electron transfer activity)|go:"GO:0009897"(external side of plasma membrane)|go:"GO:0034599"(cellular response to oxidative stress)|go:"GO:0045454"(cell redox homeostasis)|go:"GO:0050660"(flavin adenine dinucleotide binding)|go:"GO:0050661"(NADP binding)|go:"GO:0070062"(extracellular exosome)|interpro:IPR001100(Pyridine nucleotide-disulphide oxidoreductase, class I)|interpro:IPR004099(Pyridine nucleotide-disulphide oxidoreductase, dimerisation)|refseq:NP_000628.2|interpro:IPR023753|interpro:IPR006322(Glutathione reductase, animal and bacterial)|interpro:IPR012999(Pyridine nucleotide-disulphide oxidoreductase, class I, active site)|interpro:IPR016156(FAD/NAD-linked reductase, dimerisation)|interpro:IPR036188|rcsb pdb:1ALG|rcsb pdb:1BWC|rcsb pdb:1DNC|rcsb pdb:1GRA|rcsb pdb:1GRB|rcsb pdb:1GRE|rcsb pdb:1GRF|rcsb pdb:1GRG|rcsb pdb:1GRH|rcsb pdb:1GRT|rcsb pdb:1GSN|rcsb pdb:1K4Q|rcsb pdb:1XAN|rcsb pdb:2AAQ|rcsb pdb:2GH5|rcsb pdb:2GRT|rcsb pdb:3DJG|rcsb pdb:3DJJ|rcsb pdb:3DK4|rcsb pdb:3DK8|rcsb pdb:3DK9|rcsb pdb:3GRS|rcsb pdb:3GRT|rcsb pdb:3SQP|rcsb pdb:4GR1|rcsb pdb:4GRT|rcsb pdb:5GRT|reactome:R-HSA-2408550|reactome:R-HSA-3299685|reactome:R-HSA-499943|reactome:R-HSA-5628897|refseq:NP_001182031.1|refseq:NP_001182032.1|refseq:NP_001182033.1 - - - figure legend:Fig.2A,Supp Table S5|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-testis)|taxid:9606(Homo sapiens) - 2020/03/24 2021/11/30 rogid:ZE4tXTFi7lUCcIbCL4KHzY3a6xM9606 rogid:7vVXBCpDFlu835Jcm+ZeGReIA+Q9606 rigid:/AFat0DrynAJ5ofEnoPSTThlxCE false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9BY14 uniprotkb:Q9Y3Z3 intact:EBI-12549378|ensembl:ENSP00000472769|uniprotkb:Q7L5R2|uniprotkb:Q9BPY7 intact:EBI-1054601|uniprotkb:Q5JXG8|uniprotkb:Q9H004|uniprotkb:Q9H005|uniprotkb:Q9H3U9|uniprotkb:B4E2A5|uniprotkb:Q8N491|uniprotkb:E1P5V2|ensembl:ENSP00000493536|ensembl:ENSP00000495667|ensembl:ENSP00000506877|ensembl:ENSP00000507178 psi-mi:tx101_human(display_long)|uniprotkb:TEX101(gene name)|psi-mi:TEX101(display_short)|uniprotkb:Cell surface receptor NYD-SP8(gene name synonym)|uniprotkb:SGRG(gene name synonym)|uniprotkb:Scleroderma-associated autoantigen(gene name synonym)|uniprotkb:Spermatogenesis-related gene protein(gene name synonym)|uniprotkb:UNQ867/PRO1884(orf name) psi-mi:samh1_human(display_long)|uniprotkb:Dendritic cell-derived IFNG-induced protein(gene name synonym)|uniprotkb:Monocyte protein 5(gene name synonym)|uniprotkb:SAMHD1(gene name)|psi-mi:SAMHD1(display_short)|uniprotkb:MOP5(gene name synonym)|uniprotkb:SAM domain and HD domain-containing protein 1(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Schiza et al. (2018) imex:IM-28077|pubmed:30097533 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-25505061|imex:IM-28077-3 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000131126(gene)|ensembl:ENST00000598265(transcript)|go:"GO:0001669"(acrosomal vesicle)|go:"GO:0002080"(acrosomal membrane)|go:"GO:0005576"(extracellular region)|go:"GO:0005886"(plasma membrane)|go:"GO:0007339"(binding of sperm to zona pellucida)|go:"GO:0009566"(fertilization)|go:"GO:0030317"(flagellated sperm motility)|go:"GO:0044853"(plasma membrane raft)|go:"GO:0046658"(anchored component of plasma membrane)|go:"GO:1901317"(regulation of flagellated sperm motility)|interpro:IPR016054(Ly-6 antigen / uPA receptor -like)|rcsb pdb:7BPR|reactome:R-HSA-163125|refseq:NP_001123483.1|refseq:NP_113639.4 refseq:NP_056289.2|refseq:XP_005260441.1|ensembl:ENSG00000101347(gene)|ensembl:ENST00000646673(transcript)|ensembl:ENST00000646869(transcript)|ensembl:ENST00000683766(transcript)|go:"GO:0000724"(double-strand break repair via homologous recombination)|go:"GO:0003676"(nucleic acid binding)|ensembl:ENST00000682773(transcript)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0004540"(ribonuclease activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0006203"(dGTP catabolic process)|go:"GO:0006955"(immune response)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0008270"(zinc ion binding)|go:"GO:0008832"(dGTPase activity)|go:"GO:0009264"(deoxyribonucleotide catabolic process)|go:"GO:0016446"(somatic hypermutation of immunoglobulin genes)|go:"GO:0016793"(triphosphoric monoester hydrolase activity)|go:"GO:0032567"(dGTP binding)|go:"GO:0035861"(site of double-strand break)|go:"GO:0042802"(identical protein binding)|go:"GO:0045087"(innate immune response)|go:"GO:0045088"(regulation of innate immune response)|go:"GO:0046061"(dATP catabolic process)|go:"GO:0051289"(protein homotetramerization)|go:"GO:0051607"(defense response to virus)|go:"GO:0060339"(negative regulation of type I interferon-mediated signaling pathway)|go:"GO:0097197"(tetraspanin-enriched microdomain)|go:"GO:0106375"(deoxynucleoside triphosphate hydrolase activity)|go:"GO:0110025"(DNA strand resection involved in replication fork processing)|interpro:IPR001660(Sterile alpha motif SAM)|interpro:IPR003607(Metal-dependent phosphohydrolase, HD region)|interpro:IPR006674(Metal-dependent phosphohydrolase, HD region, subdomain)|interpro:IPR013761(Sterile alpha motif-type)|mint:Q9Y3Z3|rcsb pdb:2E8O|rcsb pdb:3U1N|rcsb pdb:4BZB|rcsb pdb:4BZC|rcsb pdb:4CC9|rcsb pdb:4MZ7|rcsb pdb:4Q7H|rcsb pdb:4QFX|rcsb pdb:4QFY|rcsb pdb:4QFZ|rcsb pdb:4QG0|rcsb pdb:4QG1|rcsb pdb:4QG2|rcsb pdb:4QG4|rcsb pdb:4RXO|rcsb pdb:4RXP|rcsb pdb:4RXQ|rcsb pdb:4RXR|rcsb pdb:4RXS|rcsb pdb:4TNP|rcsb pdb:4TNQ|rcsb pdb:4TNR|rcsb pdb:4TNX|rcsb pdb:4TNY|rcsb pdb:4TNZ|rcsb pdb:4TO0|rcsb pdb:4TO1|rcsb pdb:4TO2|rcsb pdb:4TO3|rcsb pdb:4TO4|rcsb pdb:4TO5|rcsb pdb:6DW4|rcsb pdb:6DW5|rcsb pdb:6DW7|rcsb pdb:6DWD|rcsb pdb:6DWJ|rcsb pdb:6DWK|rcsb pdb:6TX0|rcsb pdb:6TXA|rcsb pdb:6TXC|rcsb pdb:6TXE|rcsb pdb:6TXF|rcsb pdb:6U6X|rcsb pdb:6U6Y|rcsb pdb:6U6Z|rcsb pdb:6XU1|rcsb pdb:6YOM|rcsb pdb:7A5Y|reactome:R-HSA-8956319|rcsb pdb:4TO6|rcsb pdb:4ZWE|reactome:R-HSA-909733|rcsb pdb:4ZWG|rcsb pdb:5AO0|rcsb pdb:5AO1|rcsb pdb:5AO2|rcsb pdb:5AO3|rcsb pdb:5AO4|rcsb pdb:6CM2|rcsb pdb:6DW3|dip:DIP-50704N - - - figure legend:Fig.2A,Supp Table S5|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-testis)|taxid:9606(Homo sapiens) - 2020/03/24 2021/11/30 rogid:ZE4tXTFi7lUCcIbCL4KHzY3a6xM9606 rogid:cxoMHFueO9JuBg2d0PoGCYoOwY09606 rigid:/AFat0DrynAJ5ofEnoPSTThlxCE false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9BY14 uniprotkb:P55769 intact:EBI-12549378|ensembl:ENSP00000472769|uniprotkb:Q7L5R2|uniprotkb:Q9BPY7 intact:EBI-712228|ensembl:ENSP00000215956|ensembl:ENSP00000383949|ensembl:ENSP00000497142 psi-mi:tx101_human(display_long)|uniprotkb:TEX101(gene name)|psi-mi:TEX101(display_short)|uniprotkb:Cell surface receptor NYD-SP8(gene name synonym)|uniprotkb:SGRG(gene name synonym)|uniprotkb:Scleroderma-associated autoantigen(gene name synonym)|uniprotkb:Spermatogenesis-related gene protein(gene name synonym)|uniprotkb:UNQ867/PRO1884(orf name) psi-mi:nh2l1_human(display_long)|uniprotkb:SNU13(gene name)|psi-mi:SNU13(display_short)|uniprotkb:High mobility group-like nuclear protein 2 homolog 1(gene name synonym)|uniprotkb:NHP2L1(gene name synonym)|uniprotkb:OTK27(gene name synonym)|uniprotkb:SNU13 homolog(gene name synonym)|uniprotkb:U4/U6.U5 small nuclear ribonucleoprotein SNU13(gene name synonym)|uniprotkb:U4/U6.U5 tri-snRNP 15.5 kDa protein(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Schiza et al. (2018) imex:IM-28077|pubmed:30097533 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-25505061|imex:IM-28077-3 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000131126(gene)|ensembl:ENST00000598265(transcript)|go:"GO:0001669"(acrosomal vesicle)|go:"GO:0002080"(acrosomal membrane)|go:"GO:0005576"(extracellular region)|go:"GO:0005886"(plasma membrane)|go:"GO:0007339"(binding of sperm to zona pellucida)|go:"GO:0009566"(fertilization)|go:"GO:0030317"(flagellated sperm motility)|go:"GO:0044853"(plasma membrane raft)|go:"GO:0046658"(anchored component of plasma membrane)|go:"GO:1901317"(regulation of flagellated sperm motility)|interpro:IPR016054(Ly-6 antigen / uPA receptor -like)|rcsb pdb:7BPR|reactome:R-HSA-163125|refseq:NP_001123483.1|refseq:NP_113639.4 ensembl:ENSG00000100138(gene)|ensembl:ENST00000215956(transcript)|ensembl:ENST00000401959(transcript)|ensembl:ENST00000648674(transcript)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0000470"(maturation of LSU-rRNA)|go:"GO:0000492"(box C/D snoRNP assembly)|go:"GO:0001651"(dense fibrillar component)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005690"(U4atac snRNP)|go:"GO:0005730"(nucleolus)|go:"GO:0007338"(single fertilization)|go:"GO:0030490"(maturation of SSU-rRNA)|go:"GO:0030621"(U4 snRNA binding)|go:"GO:0030622"(U4atac snRNA binding)|go:"GO:0031428"(box C/D RNP complex)|go:"GO:0032040"(small-subunit processome)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034511"(U3 snoRNA binding)|go:"GO:0034512"(box C/D RNA binding)|go:"GO:0046540"(U4/U6 x U5 tri-snRNP complex)|go:"GO:0051117"(ATPase binding)|go:"GO:0071005"(U2-type precatalytic spliceosome)|go:"GO:0071011"(precatalytic spliceosome)|interpro:IPR002415(High mobility group-like nuclear protein)|interpro:IPR004037(Ribosomal protein L7Ae)|interpro:IPR004038(Ribosomal protein L7Ae/L30e/S12e/Gadd45)|interpro:IPR018492|interpro:IPR029064|mint:P55769|rcsb pdb:1E7K|rcsb pdb:2JNB|rcsb pdb:2OZB|rcsb pdb:3JCR|rcsb pdb:3SIU|rcsb pdb:3SIV|rcsb pdb:5O9Z|rcsb pdb:6AH0|rcsb pdb:6AHD|rcsb pdb:6QW6|rcsb pdb:6QX9|reactome:R-HSA-6790901|reactome:R-HSA-6791226|reactome:R-HSA-72163|reactome:R-HSA-72165|refseq:NP_001003796.1|refseq:NP_004999.1 - - - figure legend:Fig.2A,Supp Table S5|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-testis)|taxid:9606(Homo sapiens) - 2020/03/24 2021/11/30 rogid:ZE4tXTFi7lUCcIbCL4KHzY3a6xM9606 rogid:ZMkqsDfMCrTlT/kJxillOA8839E9606 rigid:/AFat0DrynAJ5ofEnoPSTThlxCE false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9BY14 uniprotkb:P53396 intact:EBI-12549378|ensembl:ENSP00000472769|uniprotkb:Q7L5R2|uniprotkb:Q9BPY7 intact:EBI-1042794|uniprotkb:Q13037|uniprotkb:Q9BRL0|uniprotkb:B4E3P0|uniprotkb:B4DIM0|ensembl:ENSP00000253792|ensembl:ENSP00000466259 psi-mi:tx101_human(display_long)|uniprotkb:TEX101(gene name)|psi-mi:TEX101(display_short)|uniprotkb:Cell surface receptor NYD-SP8(gene name synonym)|uniprotkb:SGRG(gene name synonym)|uniprotkb:Scleroderma-associated autoantigen(gene name synonym)|uniprotkb:Spermatogenesis-related gene protein(gene name synonym)|uniprotkb:UNQ867/PRO1884(orf name) psi-mi:acly_human(display_long)|uniprotkb:ACLY(gene name)|psi-mi:ACLY(display_short)|uniprotkb:"ATP-citrate (pro-S-)-lyase"(gene name synonym)|uniprotkb:Citrate cleavage enzyme(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Schiza et al. (2018) imex:IM-28077|pubmed:30097533 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-25505061|imex:IM-28077-3 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000131126(gene)|ensembl:ENST00000598265(transcript)|go:"GO:0001669"(acrosomal vesicle)|go:"GO:0002080"(acrosomal membrane)|go:"GO:0005576"(extracellular region)|go:"GO:0005886"(plasma membrane)|go:"GO:0007339"(binding of sperm to zona pellucida)|go:"GO:0009566"(fertilization)|go:"GO:0030317"(flagellated sperm motility)|go:"GO:0044853"(plasma membrane raft)|go:"GO:0046658"(anchored component of plasma membrane)|go:"GO:1901317"(regulation of flagellated sperm motility)|interpro:IPR016054(Ly-6 antigen / uPA receptor -like)|rcsb pdb:7BPR|reactome:R-HSA-163125|refseq:NP_001123483.1|refseq:NP_113639.4 refseq:NP_001087.2|refseq:NP_942127.1|go:"GO:0070062"(extracellular exosome)|go:"GO:1904813"(ficolin-1-rich granule lumen)|interpro:IPR002020(Citrate synthase-like)|interpro:IPR003781(CoA-binding)|interpro:IPR005811(ATP-citrate lyase/succinyl-CoA ligase)|interpro:IPR014608(ATP-citrate synthase)|ensembl:ENSG00000131473(gene)|ensembl:ENST00000352035(transcript)|ensembl:ENST00000590151(transcript)|go:"GO:0003878"(ATP citrate synthase activity)|interpro:IPR016102(Succinyl-CoA synthetase-like)|go:"GO:0005524"(ATP binding)|interpro:IPR016143(Citrate synthase-like, small alpha subdomain)|interpro:IPR017440(ATP-citrate lyase/succinyl-CoA ligase, active site)|interpro:IPR017866|interpro:IPR032263|go:"GO:0005576"(extracellular region)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006085"(acetyl-CoA biosynthetic process)|go:"GO:0006101"(citrate metabolic process)|go:"GO:0006107"(oxaloacetate metabolic process)|go:"GO:0006633"(fatty acid biosynthetic process)|go:"GO:0006695"(cholesterol biosynthetic process)|go:"GO:0008610"(lipid biosynthetic process)|go:"GO:0015936"(coenzyme A metabolic process)|go:"GO:0016020"(membrane)|go:"GO:0035578"(azurophil granule lumen)|go:"GO:0046872"(metal ion binding)|interpro:IPR033847|rcsb pdb:6O0H|interpro:IPR036291|rcsb pdb:6POE|interpro:IPR036969|rcsb pdb:6POF|rcsb pdb:6QFB|mint:P53396|rcsb pdb:6UI9|rcsb pdb:6UIA|rcsb pdb:3MWD|rcsb pdb:6UUW|rcsb pdb:6UUZ|rcsb pdb:6UV5|rcsb pdb:6Z2H|rcsb pdb:7LIW|rcsb pdb:7LJ9|rcsb pdb:7LLA|reactome:R-HSA-163765|rcsb pdb:3MWE|reactome:R-HSA-6798695|reactome:R-HSA-75105|rcsb pdb:3PFF|rcsb pdb:5TDE|rcsb pdb:5TDF|rcsb pdb:5TDM|rcsb pdb:5TDZ|rcsb pdb:5TE1|rcsb pdb:5TEQ|rcsb pdb:5TES|rcsb pdb:5TET|rcsb pdb:6HXH|rcsb pdb:6HXK|rcsb pdb:6HXL|rcsb pdb:6HXM|refseq:XP_005257452.1|refseq:NP_001290203.1|refseq:NP_001290204.1 - - - figure legend:Fig.2A,Supp Table S5|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-testis)|taxid:9606(Homo sapiens) - 2020/03/24 2021/11/30 rogid:ZE4tXTFi7lUCcIbCL4KHzY3a6xM9606 rogid:NaxO5aRi08GTrEV9aIboUdTlpAs9606 rigid:/AFat0DrynAJ5ofEnoPSTThlxCE false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9BY14 uniprotkb:P50453 intact:EBI-12549378|ensembl:ENSP00000472769|uniprotkb:Q7L5R2|uniprotkb:Q9BPY7 intact:EBI-711626|uniprotkb:Q5TD03|uniprotkb:B2RBW3|ensembl:ENSP00000370074 psi-mi:tx101_human(display_long)|uniprotkb:TEX101(gene name)|psi-mi:TEX101(display_short)|uniprotkb:Cell surface receptor NYD-SP8(gene name synonym)|uniprotkb:SGRG(gene name synonym)|uniprotkb:Scleroderma-associated autoantigen(gene name synonym)|uniprotkb:Spermatogenesis-related gene protein(gene name synonym)|uniprotkb:UNQ867/PRO1884(orf name) psi-mi:spb9_human(display_long)|uniprotkb:SERPINB9(gene name)|psi-mi:SERPINB9(display_short)|uniprotkb:PI9(gene name synonym)|uniprotkb:Cytoplasmic antiproteinase 3(gene name synonym)|uniprotkb:Peptidase inhibitor 9(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Schiza et al. (2018) imex:IM-28077|pubmed:30097533 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-25505061|imex:IM-28077-3 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000131126(gene)|ensembl:ENST00000598265(transcript)|go:"GO:0001669"(acrosomal vesicle)|go:"GO:0002080"(acrosomal membrane)|go:"GO:0005576"(extracellular region)|go:"GO:0005886"(plasma membrane)|go:"GO:0007339"(binding of sperm to zona pellucida)|go:"GO:0009566"(fertilization)|go:"GO:0030317"(flagellated sperm motility)|go:"GO:0044853"(plasma membrane raft)|go:"GO:0046658"(anchored component of plasma membrane)|go:"GO:1901317"(regulation of flagellated sperm motility)|interpro:IPR016054(Ly-6 antigen / uPA receptor -like)|rcsb pdb:7BPR|reactome:R-HSA-163125|refseq:NP_001123483.1|refseq:NP_113639.4 ensembl:ENSG00000170542(gene)|ensembl:ENST00000380698(transcript)|go:"GO:0002020"(protease binding)|refseq:NP_004146.1|refseq:XP_005249241.1|go:"GO:0043027"(cysteine-type endopeptidase inhibitor activity involved in apoptotic process)|go:"GO:0004867"(serine-type endopeptidase inhibitor activity)|go:"GO:0005615"(extracellular space)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0006955"(immune response)|go:"GO:0009617"(response to bacterium)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010951"(negative regulation of endopeptidase activity)|go:"GO:0016020"(membrane)|go:"GO:0033668"(negative regulation by symbiont of host apoptotic process)|go:"GO:0042270"(protection from natural killer cell mediated cytotoxicity)|go:"GO:0002448"(mast cell mediated immunity)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0062023"(collagen-containing extracellular matrix)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071391"(cellular response to estrogen stimulus)|interpro:IPR000215(Protease inhibitor I4, serpin)|interpro:IPR000240(Serpin B9 and maspin)|interpro:IPR023795|interpro:IPR023796|interpro:IPR036186|interpro:IPR042178|interpro:IPR042185 - - - figure legend:Fig.2A,Supp Table S5|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-testis)|taxid:9606(Homo sapiens) - 2020/03/24 2021/11/30 rogid:ZE4tXTFi7lUCcIbCL4KHzY3a6xM9606 rogid:BFT8YUM1DhX4hjTmzVI4pZbOqxk9606 rigid:/AFat0DrynAJ5ofEnoPSTThlxCE false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9BY14 uniprotkb:Q15008 intact:EBI-12549378|ensembl:ENSP00000472769|uniprotkb:Q7L5R2|uniprotkb:Q9BPY7 intact:EBI-359701|uniprotkb:E9PHI9|uniprotkb:A8K2E0|ensembl:ENSP00000295901|uniprotkb:Q6UV22 psi-mi:tx101_human(display_long)|uniprotkb:TEX101(gene name)|psi-mi:TEX101(display_short)|uniprotkb:Cell surface receptor NYD-SP8(gene name synonym)|uniprotkb:SGRG(gene name synonym)|uniprotkb:Scleroderma-associated autoantigen(gene name synonym)|uniprotkb:Spermatogenesis-related gene protein(gene name synonym)|uniprotkb:UNQ867/PRO1884(orf name) psi-mi:psmd6_human(display_long)|uniprotkb:PSMD6(gene name)|psi-mi:PSMD6(display_short)|uniprotkb:KIAA0107(gene name synonym)|uniprotkb:PFAAP4(gene name synonym)|uniprotkb:26S proteasome regulatory subunit S10(gene name synonym)|uniprotkb:p42A(gene name synonym)|uniprotkb:Proteasome regulatory particle subunit p44S10(gene name synonym)|uniprotkb:Phosphonoformate immuno-associated protein 4(gene name synonym)|uniprotkb:Breast cancer-associated protein SGA-113M(gene name synonym)|uniprotkb:26S proteasome regulatory subunit RPN7(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Schiza et al. (2018) imex:IM-28077|pubmed:30097533 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-25505061|imex:IM-28077-3 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000131126(gene)|ensembl:ENST00000598265(transcript)|go:"GO:0001669"(acrosomal vesicle)|go:"GO:0002080"(acrosomal membrane)|go:"GO:0005576"(extracellular region)|go:"GO:0005886"(plasma membrane)|go:"GO:0007339"(binding of sperm to zona pellucida)|go:"GO:0009566"(fertilization)|go:"GO:0030317"(flagellated sperm motility)|go:"GO:0044853"(plasma membrane raft)|go:"GO:0046658"(anchored component of plasma membrane)|go:"GO:1901317"(regulation of flagellated sperm motility)|interpro:IPR016054(Ly-6 antigen / uPA receptor -like)|rcsb pdb:7BPR|reactome:R-HSA-163125|refseq:NP_001123483.1|refseq:NP_113639.4 refseq:NP_055629.1|ensembl:ENSG00000163636(gene)|ensembl:ENST00000295901(transcript)|go:"GO:0000502"(proteasome complex)|go:"GO:0005576"(extracellular region)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005838"(proteasome regulatory particle)|go:"GO:0022624"(proteasome accessory complex)|go:"GO:0030234"(enzyme regulator activity)|go:"GO:0034774"(secretory granule lumen)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:1904813"(ficolin-1-rich granule lumen)|interpro:IPR000717(Proteasome component region PCI)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR019585|interpro:IPR035268|interpro:IPR036390|mint:Q15008|rcsb pdb:5GJQ|rcsb pdb:5GJR|rcsb pdb:5L4K|rcsb pdb:5LN3|rcsb pdb:5M32|rcsb pdb:5T0C|rcsb pdb:5T0G|rcsb pdb:5T0H|rcsb pdb:5T0I|rcsb pdb:5T0J|rcsb pdb:5VFP|rcsb pdb:5VFQ|rcsb pdb:5VFR|rcsb pdb:5VFS|rcsb pdb:5VFT|rcsb pdb:5VFU|rcsb pdb:5VGZ|rcsb pdb:5VHF|rcsb pdb:5VHH|rcsb pdb:5VHI|rcsb pdb:5VHS|rcsb pdb:6MSB|rcsb pdb:6MSD|rcsb pdb:6MSG|rcsb pdb:6MSH|reactome:R-HSA-5358346|reactome:R-HSA-1236978|rcsb pdb:6MSJ|rcsb pdb:6MSK|rcsb pdb:6WJD|rcsb pdb:6WJN|reactome:R-HSA-1169091|reactome:R-HSA-1234176|reactome:R-HSA-174084|reactome:R-HSA-174113|reactome:R-HSA-174154|reactome:R-HSA-174178|reactome:R-HSA-174184|reactome:R-HSA-180534|reactome:R-HSA-180585|reactome:R-HSA-1236974|reactome:R-HSA-187577|reactome:R-HSA-195253|reactome:R-HSA-202424|reactome:R-HSA-211733|reactome:R-HSA-2467813|reactome:R-HSA-2871837|reactome:R-HSA-349425|reactome:R-HSA-350562|reactome:R-HSA-382556|reactome:R-HSA-450408|reactome:R-HSA-4608870|reactome:R-HSA-4641257|reactome:R-HSA-4641258|reactome:R-HSA-5362768|reactome:R-HSA-5607761|reactome:R-HSA-5607764|reactome:R-HSA-5610780|reactome:R-HSA-5610783|reactome:R-HSA-5610785|reactome:R-HSA-5632684|reactome:R-HSA-5658442|reactome:R-HSA-5668541|reactome:R-HSA-5676590|reactome:R-HSA-5678895|reactome:R-HSA-5687128|reactome:R-HSA-5689603|reactome:R-HSA-5689880|reactome:R-HSA-6798695|reactome:R-HSA-68827|reactome:R-HSA-68949|reactome:R-HSA-69017|reactome:R-HSA-75815|reactome:R-HSA-8852276|reactome:R-HSA-8854050|reactome:R-HSA-8932339|reactome:R-HSA-8939236|reactome:R-HSA-8939902|reactome:R-HSA-8941858|reactome:R-HSA-8948751|reactome:R-HSA-8951664|reactome:R-HSA-9010553|reactome:R-HSA-9020702|reactome:R-HSA-9604323|reactome:R-HSA-983168|reactome:R-HSA-69601|reactome:R-HSA-69481|refseq:NP_001258708.1|refseq:NP_001258709.1|refseq:NP_001258710.1|dip:DIP-27590N - - - figure legend:Fig.2A,Supp Table S5|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-testis)|taxid:9606(Homo sapiens) - 2020/03/24 2021/11/30 rogid:ZE4tXTFi7lUCcIbCL4KHzY3a6xM9606 rogid:ULOM02v6J56vZLlAGn7wN3N6Efw9606 rigid:/AFat0DrynAJ5ofEnoPSTThlxCE false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9BY14 uniprotkb:P61106 intact:EBI-12549378|ensembl:ENSP00000472769|uniprotkb:Q7L5R2|uniprotkb:Q9BPY7 intact:EBI-1056404|uniprotkb:P35287|uniprotkb:Q5JVD4|uniprotkb:Q6Q7K5|uniprotkb:Q969L0|uniprotkb:Q9UI11|uniprotkb:B3KR31|ensembl:ENSP00000362946 psi-mi:tx101_human(display_long)|uniprotkb:TEX101(gene name)|psi-mi:TEX101(display_short)|uniprotkb:Cell surface receptor NYD-SP8(gene name synonym)|uniprotkb:SGRG(gene name synonym)|uniprotkb:Scleroderma-associated autoantigen(gene name synonym)|uniprotkb:Spermatogenesis-related gene protein(gene name synonym)|uniprotkb:UNQ867/PRO1884(orf name) psi-mi:rab14_human(display_long)|uniprotkb:RAB14(gene name)|psi-mi:RAB14(display_short) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Schiza et al. (2018) imex:IM-28077|pubmed:30097533 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-25505061|imex:IM-28077-3 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000131126(gene)|ensembl:ENST00000598265(transcript)|go:"GO:0001669"(acrosomal vesicle)|go:"GO:0002080"(acrosomal membrane)|go:"GO:0005576"(extracellular region)|go:"GO:0005886"(plasma membrane)|go:"GO:0007339"(binding of sperm to zona pellucida)|go:"GO:0009566"(fertilization)|go:"GO:0030317"(flagellated sperm motility)|go:"GO:0044853"(plasma membrane raft)|go:"GO:0046658"(anchored component of plasma membrane)|go:"GO:1901317"(regulation of flagellated sperm motility)|interpro:IPR016054(Ly-6 antigen / uPA receptor -like)|rcsb pdb:7BPR|reactome:R-HSA-163125|refseq:NP_001123483.1|refseq:NP_113639.4 refseq:NP_057406.2|ensembl:ENSG00000119396(gene)|ensembl:ENST00000373840(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005764"(lysosome)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005769"(early endosome)|go:"GO:0005770"(late endosome)|go:"GO:0005791"(rough endoplasmic reticulum)|go:"GO:0005795"(Golgi stack)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006895"(Golgi to endosome transport)|go:"GO:0008543"(fibroblast growth factor receptor signaling pathway)|go:"GO:0012505"(endomembrane system)|go:"GO:0016192"(vesicle-mediated transport)|go:"GO:0019003"(GDP binding)|go:"GO:0030140"(trans-Golgi network transport vesicle)|go:"GO:0031489"(myosin V binding)|go:"GO:0031901"(early endosome membrane)|go:"GO:0032456"(endocytic recycling)|go:"GO:0032880"(regulation of protein localization)|go:"GO:0042175"(nuclear outer membrane-endoplasmic reticulum membrane network)|go:"GO:0042742"(defense response to bacterium)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0045335"(phagocytic vesicle)|go:"GO:0045995"(regulation of embryonic development)|go:"GO:0046907"(intracellular transport)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0055037"(recycling endosome)|go:"GO:0055038"(recycling endosome membrane)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070821"(tertiary granule membrane)|go:"GO:0090382"(phagosome maturation)|go:"GO:0090387"(phagolysosome assembly involved in apoptotic cell clearance)|interpro:IPR001806(Ras GTPase)|interpro:IPR005225(Small GTP-binding protein)|interpro:IPR027417|interpro:IPR030702|mint:P61106|rcsb pdb:1Z0F|rcsb pdb:4D0G|rcsb pdb:4DRZ|reactome:R-HSA-1445148|reactome:R-HSA-1660499|reactome:R-HSA-6798695|reactome:R-HSA-8873719|reactome:R-HSA-8876198|dip:DIP-42491N - - - figure legend:Fig.2A,Supp Table S5|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-testis)|taxid:9606(Homo sapiens) - 2020/03/24 2021/11/30 rogid:ZE4tXTFi7lUCcIbCL4KHzY3a6xM9606 rogid:qFP8UXDCPt/RcLTWlZLaitH2LF49606 rigid:/AFat0DrynAJ5ofEnoPSTThlxCE false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9BY14 uniprotkb:O14964 intact:EBI-12549378|ensembl:ENSP00000472769|uniprotkb:Q7L5R2|uniprotkb:Q9BPY7 intact:EBI-740220|uniprotkb:Q9NR36|ensembl:ENSP00000331201|ensembl:ENSP00000504106 psi-mi:tx101_human(display_long)|uniprotkb:TEX101(gene name)|psi-mi:TEX101(display_short)|uniprotkb:Cell surface receptor NYD-SP8(gene name synonym)|uniprotkb:SGRG(gene name synonym)|uniprotkb:Scleroderma-associated autoantigen(gene name synonym)|uniprotkb:Spermatogenesis-related gene protein(gene name synonym)|uniprotkb:UNQ867/PRO1884(orf name) psi-mi:hgs_human(display_long)|uniprotkb:Protein pp110(gene name synonym)|uniprotkb:Hrs(gene name synonym)|uniprotkb:HGS(gene name)|psi-mi:HGS(display_short)|uniprotkb:HRS(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Schiza et al. (2018) imex:IM-28077|pubmed:30097533 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-25505061|imex:IM-28077-3 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000131126(gene)|ensembl:ENST00000598265(transcript)|go:"GO:0001669"(acrosomal vesicle)|go:"GO:0002080"(acrosomal membrane)|go:"GO:0005576"(extracellular region)|go:"GO:0005886"(plasma membrane)|go:"GO:0007339"(binding of sperm to zona pellucida)|go:"GO:0009566"(fertilization)|go:"GO:0030317"(flagellated sperm motility)|go:"GO:0044853"(plasma membrane raft)|go:"GO:0046658"(anchored component of plasma membrane)|go:"GO:1901317"(regulation of flagellated sperm motility)|interpro:IPR016054(Ly-6 antigen / uPA receptor -like)|rcsb pdb:7BPR|reactome:R-HSA-163125|refseq:NP_001123483.1|refseq:NP_113639.4 refseq:NP_004703.1|dip:DIP-29050N|ensembl:ENSG00000185359(gene)|ensembl:ENST00000329138(transcript)|ensembl:ENST00000676546(transcript)|go:"GO:0005764"(lysosome)|go:"GO:0005768"(endosome)|go:"GO:0005769"(early endosome)|go:"GO:0005829"(cytosol)|go:"GO:0006622"(protein targeting to lysosome)|go:"GO:0007165"(signal transduction)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0010324"(membrane invagination)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010642"(negative regulation of platelet-derived growth factor receptor signaling pathway)|go:"GO:0016197"(endosomal transport)|go:"GO:0016236"(macroautophagy)|go:"GO:0016525"(negative regulation of angiogenesis)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030948"(negative regulation of vascular endothelial growth factor receptor signaling pathway)|go:"GO:0031901"(early endosome membrane)|go:"GO:0032585"(multivesicular body membrane)|go:"GO:0033565"(ESCRT-0 complex)|go:"GO:0035091"(phosphatidylinositol binding)|go:"GO:0036258"(multivesicular body assembly)|go:"GO:0042176"(regulation of protein catabolic process)|go:"GO:0043130"(ubiquitin binding)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0043405"(regulation of MAP kinase activity)|go:"GO:0044389"(ubiquitin-like protein ligase binding)|go:"GO:0046426"(negative regulation of receptor signaling pathway via JAK-STAT)|go:"GO:0046872"(metal ion binding)|go:"GO:0070062"(extracellular exosome)|go:"GO:0072657"(protein localization to membrane)|go:"GO:0097013"(phagocytic vesicle lumen)|go:"GO:1903543"(positive regulation of exosomal secretion)|interpro:IPR000306(Zinc finger, FYVE-type)|interpro:IPR002014(VHS)|interpro:IPR003903(Ubiquitin interacting motif)|interpro:IPR008942(ENTH/VHS)|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017073(Ubiquitin binding protein, Hrs/VPS27)|interpro:IPR017455(Zinc finger, FYVE-related)|interpro:IPR024641|mint:O14964|rcsb pdb:2D3G|rcsb pdb:3F1I|rcsb pdb:3OBQ|rcsb pdb:3ZYQ|rcsb pdb:4AVX|reactome:R-HSA-182971|reactome:R-HSA-432720|reactome:R-HSA-5689880|reactome:R-HSA-6807004|reactome:R-HSA-8856825|reactome:R-HSA-8856828|reactome:R-HSA-8875360|reactome:R-HSA-9013420|reactome:R-HSA-917729|reactome:R-HSA-9635644|reactome:R-HSA-9636383|reactome:R-HSA-9706019 - - - figure legend:Fig.2A,Supp Table S5|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-testis)|taxid:9606(Homo sapiens) - 2020/03/24 2021/11/30 rogid:ZE4tXTFi7lUCcIbCL4KHzY3a6xM9606 rogid:z/AnREuqEpyJ9/Zj6JFCJCJem1I9606 rigid:/AFat0DrynAJ5ofEnoPSTThlxCE false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9BY14 uniprotkb:Q8N163 intact:EBI-12549378|ensembl:ENSP00000472769|uniprotkb:Q7L5R2|uniprotkb:Q9BPY7 intact:EBI-355410|uniprotkb:A6NL03|uniprotkb:Q6P0Q9|uniprotkb:Q8N3G7|uniprotkb:Q8N8M1|uniprotkb:Q8TF34|uniprotkb:Q9H9Q9|uniprotkb:Q9HD12|uniprotkb:Q9NT55|ensembl:ENSP00000310670|ensembl:ENSP00000373930|uniprotkb:B2RB79|uniprotkb:D3DSR6 psi-mi:tx101_human(display_long)|uniprotkb:TEX101(gene name)|psi-mi:TEX101(display_short)|uniprotkb:Cell surface receptor NYD-SP8(gene name synonym)|uniprotkb:SGRG(gene name synonym)|uniprotkb:Scleroderma-associated autoantigen(gene name synonym)|uniprotkb:Spermatogenesis-related gene protein(gene name synonym)|uniprotkb:UNQ867/PRO1884(orf name) psi-mi:ccar2_human(display_long)|uniprotkb:CCAR2(gene name)|psi-mi:CCAR2(display_short)|uniprotkb:Cell division cycle and apoptosis regulator protein 2(gene name synonym)|uniprotkb:DBC1(gene name synonym)|uniprotkb:DBIRD complex subunit KIAA1967(gene name synonym)|uniprotkb:Deleted in breast cancer gene 1 protein(gene name synonym)|uniprotkb:KIAA1967(gene name synonym)|uniprotkb:p30 DBC(gene name synonym)|uniprotkb:NET35(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Schiza et al. (2018) imex:IM-28077|pubmed:30097533 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-25505061|imex:IM-28077-3 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000131126(gene)|ensembl:ENST00000598265(transcript)|go:"GO:0001669"(acrosomal vesicle)|go:"GO:0002080"(acrosomal membrane)|go:"GO:0005576"(extracellular region)|go:"GO:0005886"(plasma membrane)|go:"GO:0007339"(binding of sperm to zona pellucida)|go:"GO:0009566"(fertilization)|go:"GO:0030317"(flagellated sperm motility)|go:"GO:0044853"(plasma membrane raft)|go:"GO:0046658"(anchored component of plasma membrane)|go:"GO:1901317"(regulation of flagellated sperm motility)|interpro:IPR016054(Ly-6 antigen / uPA receptor -like)|rcsb pdb:7BPR|reactome:R-HSA-163125|refseq:NP_001123483.1|refseq:NP_113639.4 refseq:NP_066997.3|ensembl:ENSG00000158941(gene)|ensembl:ENST00000308511(transcript)|ensembl:ENST00000389279(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000993"(RNA polymerase II complex binding)|go:"GO:0003723"(RNA binding)|go:"GO:0004857"(enzyme inhibitor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0005819"(spindle)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006397"(mRNA processing)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0007049"(cell cycle)|go:"GO:0008380"(RNA splicing)|go:"GO:0009411"(response to UV)|go:"GO:0016055"(Wnt signaling pathway)|interpro:IPR028811|mint:Q8N163|reactome:R-HSA-3371453|go:"GO:0019899"(enzyme binding)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0030374"(nuclear receptor coactivator activity)|go:"GO:0031647"(regulation of protein stability)|go:"GO:0032435"(negative regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0032784"(regulation of DNA-templated transcription, elongation)|go:"GO:0042752"(regulation of circadian rhythm)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043086"(negative regulation of catalytic activity)|go:"GO:0043653"(mitochondrial fragmentation involved in apoptotic process)|go:"GO:0044609"(DBIRD complex)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0048511"(rhythmic process)|go:"GO:0090263"(positive regulation of canonical Wnt signaling pathway)|go:"GO:0090311"(regulation of protein deacetylation)|go:"GO:1902230"(negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage)|go:"GO:2000003"(positive regulation of DNA damage checkpoint)|interpro:IPR011992(EF-Hand type)|interpro:IPR025223|interpro:IPR025224|interpro:IPR025954|dip:DIP-38122N - - - figure legend:Fig.2A,Supp Table S5|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-testis)|taxid:9606(Homo sapiens) - 2020/03/24 2021/11/30 rogid:ZE4tXTFi7lUCcIbCL4KHzY3a6xM9606 rogid:GL+fD8W0kadrYrBkuMqoKgbbITU9606 rigid:/AFat0DrynAJ5ofEnoPSTThlxCE false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9BY14 uniprotkb:O43242 intact:EBI-12549378|ensembl:ENSP00000472769|uniprotkb:Q7L5R2|uniprotkb:Q9BPY7 intact:EBI-357622|uniprotkb:Q96EI2|uniprotkb:Q9BQA4|ensembl:ENSP00000264639|uniprotkb:B4DT72|uniprotkb:B3KMW9 psi-mi:tx101_human(display_long)|uniprotkb:TEX101(gene name)|psi-mi:TEX101(display_short)|uniprotkb:Cell surface receptor NYD-SP8(gene name synonym)|uniprotkb:SGRG(gene name synonym)|uniprotkb:Scleroderma-associated autoantigen(gene name synonym)|uniprotkb:Spermatogenesis-related gene protein(gene name synonym)|uniprotkb:UNQ867/PRO1884(orf name) psi-mi:psmd3_human(display_long)|uniprotkb:PSMD3(gene name)|psi-mi:PSMD3(display_short)|uniprotkb:Proteasome subunit p58(gene name synonym)|uniprotkb:26S proteasome regulatory subunit S3(gene name synonym)|uniprotkb:26S proteasome regulatory subunit RPN3(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Schiza et al. (2018) imex:IM-28077|pubmed:30097533 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-25505061|imex:IM-28077-3 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000131126(gene)|ensembl:ENST00000598265(transcript)|go:"GO:0001669"(acrosomal vesicle)|go:"GO:0002080"(acrosomal membrane)|go:"GO:0005576"(extracellular region)|go:"GO:0005886"(plasma membrane)|go:"GO:0007339"(binding of sperm to zona pellucida)|go:"GO:0009566"(fertilization)|go:"GO:0030317"(flagellated sperm motility)|go:"GO:0044853"(plasma membrane raft)|go:"GO:0046658"(anchored component of plasma membrane)|go:"GO:1901317"(regulation of flagellated sperm motility)|interpro:IPR016054(Ly-6 antigen / uPA receptor -like)|rcsb pdb:7BPR|reactome:R-HSA-163125|refseq:NP_001123483.1|refseq:NP_113639.4 ensembl:ENSG00000108344(gene)|ensembl:ENST00000264639(transcript)|go:"GO:0000502"(proteasome complex)|go:"GO:0005576"(extracellular region)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0008541"(proteasome regulatory particle, lid subcomplex)|go:"GO:0016020"(membrane)|go:"GO:0022624"(proteasome accessory complex)|go:"GO:0030234"(enzyme regulator activity)|go:"GO:0034774"(secretory granule lumen)|go:"GO:0042176"(regulation of protein catabolic process)|go:"GO:0070062"(extracellular exosome)|go:"GO:1904813"(ficolin-1-rich granule lumen)|interpro:IPR000717(Proteasome component region PCI)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR013586(26S proteasome regulatory subunit, C-terminal)|interpro:IPR035267|interpro:IPR036390|mint:O43242|rcsb pdb:5GJQ|rcsb pdb:5GJR|rcsb pdb:5L4K|rcsb pdb:5LN3|rcsb pdb:5M32|rcsb pdb:5T0C|rcsb pdb:5T0G|rcsb pdb:5T0H|rcsb pdb:5T0I|rcsb pdb:5T0J|rcsb pdb:5VFP|rcsb pdb:5VFQ|rcsb pdb:5VFR|rcsb pdb:5VFS|rcsb pdb:5VFT|rcsb pdb:5VFU|rcsb pdb:5VGZ|rcsb pdb:5VHF|reactome:R-HSA-174113|reactome:R-HSA-174154|rcsb pdb:5VHH|rcsb pdb:5VHI|reactome:R-HSA-174178|rcsb pdb:5VHS|reactome:R-HSA-174184|rcsb pdb:6MSB|rcsb pdb:6MSD|rcsb pdb:6MSE|rcsb pdb:6MSG|rcsb pdb:6MSH|reactome:R-HSA-180534|rcsb pdb:6MSJ|reactome:R-HSA-180585|reactome:R-HSA-187577|rcsb pdb:6MSK|reactome:R-HSA-195253|reactome:R-HSA-202424|rcsb pdb:6WJD|reactome:R-HSA-211733|rcsb pdb:6WJN|reactome:R-HSA-1169091|reactome:R-HSA-1234176|reactome:R-HSA-2467813|reactome:R-HSA-2871837|reactome:R-HSA-1236974|reactome:R-HSA-1236978|reactome:R-HSA-349425|reactome:R-HSA-350562|reactome:R-HSA-174084|reactome:R-HSA-382556|reactome:R-HSA-450408|reactome:R-HSA-4608870|reactome:R-HSA-4641257|reactome:R-HSA-4641258|reactome:R-HSA-5358346|reactome:R-HSA-5362768|reactome:R-HSA-5607764|reactome:R-HSA-5610780|reactome:R-HSA-5610783|reactome:R-HSA-5610785|reactome:R-HSA-5632684|reactome:R-HSA-5658442|reactome:R-HSA-5668541|reactome:R-HSA-5676590|reactome:R-HSA-5678895|reactome:R-HSA-5687128|reactome:R-HSA-5607761|reactome:R-HSA-5689603|reactome:R-HSA-5689880|reactome:R-HSA-6798695|reactome:R-HSA-68827|reactome:R-HSA-68949|reactome:R-HSA-69017|reactome:R-HSA-69481|reactome:R-HSA-69601|reactome:R-HSA-75815|reactome:R-HSA-8852276|reactome:R-HSA-8932339|reactome:R-HSA-8939236|reactome:R-HSA-8939902|reactome:R-HSA-8941858|reactome:R-HSA-8948751|reactome:R-HSA-8951664|reactome:R-HSA-9010553|reactome:R-HSA-9020702|reactome:R-HSA-9604323|reactome:R-HSA-983168|reactome:R-HSA-8854050|refseq:NP_002800.2|dip:DIP-27571N - - - figure legend:Fig.2A,Supp Table S5|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-testis)|taxid:9606(Homo sapiens) - 2020/03/24 2021/11/30 rogid:ZE4tXTFi7lUCcIbCL4KHzY3a6xM9606 rogid:C6CStW89nIAA3mzubyv5wfBwPHk9606 rigid:/AFat0DrynAJ5ofEnoPSTThlxCE false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9BY14 uniprotkb:P49257 intact:EBI-12549378|ensembl:ENSP00000472769|uniprotkb:Q7L5R2|uniprotkb:Q9BPY7 intact:EBI-1057738|uniprotkb:Q9UQG4|uniprotkb:Q9UQG5|uniprotkb:Q9UQG6|uniprotkb:Q9UQG7|uniprotkb:Q9UQG8|uniprotkb:Q9UQG9|uniprotkb:Q9UQH0|uniprotkb:Q9UQH1|uniprotkb:Q9UQH2|uniprotkb:Q12895|uniprotkb:Q8N5I7|uniprotkb:Q9UQG1|uniprotkb:Q9UQG2|uniprotkb:Q9UQG3|ensembl:ENSP00000251047 psi-mi:tx101_human(display_long)|uniprotkb:TEX101(gene name)|psi-mi:TEX101(display_short)|uniprotkb:Cell surface receptor NYD-SP8(gene name synonym)|uniprotkb:SGRG(gene name synonym)|uniprotkb:Scleroderma-associated autoantigen(gene name synonym)|uniprotkb:Spermatogenesis-related gene protein(gene name synonym)|uniprotkb:UNQ867/PRO1884(orf name) psi-mi:lman1_human(display_long)|uniprotkb:LMAN1(gene name)|psi-mi:LMAN1(display_short)|uniprotkb:ERGIC53(gene name synonym)|uniprotkb:F5F8D(gene name synonym)|uniprotkb:ER-Golgi intermediate compartment 53 kDa protein(gene name synonym)|uniprotkb:Lectin mannose-binding 1(gene name synonym)|uniprotkb:Gp58(gene name synonym)|uniprotkb:Intracellular mannose-specific lectin MR60(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Schiza et al. (2018) imex:IM-28077|pubmed:30097533 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-25505061|imex:IM-28077-3 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000131126(gene)|ensembl:ENST00000598265(transcript)|go:"GO:0001669"(acrosomal vesicle)|go:"GO:0002080"(acrosomal membrane)|go:"GO:0005576"(extracellular region)|go:"GO:0005886"(plasma membrane)|go:"GO:0007339"(binding of sperm to zona pellucida)|go:"GO:0009566"(fertilization)|go:"GO:0030317"(flagellated sperm motility)|go:"GO:0044853"(plasma membrane raft)|go:"GO:0046658"(anchored component of plasma membrane)|go:"GO:1901317"(regulation of flagellated sperm motility)|interpro:IPR016054(Ly-6 antigen / uPA receptor -like)|rcsb pdb:7BPR|reactome:R-HSA-163125|refseq:NP_001123483.1|refseq:NP_113639.4 refseq:NP_005561.1|ensembl:ENSG00000074695(gene)|ensembl:ENST00000251047(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0005537"(mannose binding)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005793"(endoplasmic reticulum-Golgi intermediate compartment)|go:"GO:0005829"(cytosol)|go:"GO:0006457"(protein folding)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0007029"(endoplasmic reticulum organization)|go:"GO:0007030"(Golgi organization)|go:"GO:0007596"(blood coagulation)|go:"GO:0010638"(positive regulation of organelle organization)|go:"GO:0012507"(ER to Golgi transport vesicle membrane)|go:"GO:0015031"(protein transport)|go:"GO:0016020"(membrane)|go:"GO:0030017"(sarcomere)|go:"GO:0030134"(COPII-coated ER to Golgi transport vesicle)|go:"GO:0033116"(endoplasmic reticulum-Golgi intermediate compartment membrane)|go:"GO:0046872"(metal ion binding)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0062023"(collagen-containing extracellular matrix)|go:"GO:0070062"(extracellular exosome)|go:"GO:1903215"(negative regulation of protein targeting to mitochondrion)|interpro:IPR005052(Legume-like lectin)|interpro:IPR013320(Concanavalin A-like lectin/glucanase, subgroup)|interpro:IPR033085|mint:P49257|rcsb pdb:3A4U|rcsb pdb:3LCP|rcsb pdb:3WHT|rcsb pdb:3WHU|rcsb pdb:3WNX|rcsb pdb:4GKX|rcsb pdb:4GKY|rcsb pdb:4YGB|rcsb pdb:4YGC|rcsb pdb:4YGD|rcsb pdb:4YGE|reactome:R-HSA-204005|reactome:R-HSA-5694530|reactome:R-HSA-8980692|reactome:R-HSA-9013106|reactome:R-HSA-9013404|reactome:R-HSA-9013405|reactome:R-HSA-9013408|go:"GO:0016021"(integral component of membrane)|reactome:R-HSA-948021|reactome:R-HSA-9013423|dip:DIP-42188N - - - figure legend:Fig.2A,Supp Table S5|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-testis)|taxid:9606(Homo sapiens) - 2020/03/24 2021/11/30 rogid:ZE4tXTFi7lUCcIbCL4KHzY3a6xM9606 rogid:CWmvVATvXXjzMqSD0KjTBvmKKuI9606 rigid:/AFat0DrynAJ5ofEnoPSTThlxCE false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9BY14 uniprotkb:P60033 intact:EBI-12549378|ensembl:ENSP00000472769|uniprotkb:Q7L5R2|uniprotkb:Q9BPY7 intact:EBI-712921|ensembl:ENSP00000263645|uniprotkb:P18582|uniprotkb:Q5U0J6 psi-mi:tx101_human(display_long)|uniprotkb:TEX101(gene name)|psi-mi:TEX101(display_short)|uniprotkb:Cell surface receptor NYD-SP8(gene name synonym)|uniprotkb:SGRG(gene name synonym)|uniprotkb:Scleroderma-associated autoantigen(gene name synonym)|uniprotkb:Spermatogenesis-related gene protein(gene name synonym)|uniprotkb:UNQ867/PRO1884(orf name) psi-mi:cd81_human(display_long)|uniprotkb:26 kDa cell surface protein TAPA-1(gene name synonym)|uniprotkb:Target of the antiproliferative antibody 1(gene name synonym)|uniprotkb:Tetraspanin-28(gene name synonym)|uniprotkb:CD81(gene name)|psi-mi:CD81(display_short)|uniprotkb:TAPA1(gene name synonym)|uniprotkb:TSPAN28(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Schiza et al. (2018) imex:IM-28077|pubmed:30097533 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-25505061|imex:IM-28077-3 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000131126(gene)|ensembl:ENST00000598265(transcript)|go:"GO:0001669"(acrosomal vesicle)|go:"GO:0002080"(acrosomal membrane)|go:"GO:0005576"(extracellular region)|go:"GO:0005886"(plasma membrane)|go:"GO:0007339"(binding of sperm to zona pellucida)|go:"GO:0009566"(fertilization)|go:"GO:0030317"(flagellated sperm motility)|go:"GO:0044853"(plasma membrane raft)|go:"GO:0046658"(anchored component of plasma membrane)|go:"GO:1901317"(regulation of flagellated sperm motility)|interpro:IPR016054(Ly-6 antigen / uPA receptor -like)|rcsb pdb:7BPR|reactome:R-HSA-163125|refseq:NP_001123483.1|refseq:NP_113639.4 ensembl:ENSG00000110651(gene)|ensembl:ENST00000263645(transcript)|go:"GO:0000187"(obsolete activation of MAPK activity)|go:"GO:0001618"(virus receptor activity)|go:"GO:0001771"(immunological synapse formation)|go:"GO:0001772"(immunological synapse)|go:"GO:0002455"(humoral immune response mediated by circulating immunoglobulin)|go:"GO:0002863"(positive regulation of inflammatory response to antigenic stimulus)|go:"GO:0005178"(integrin binding)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0005925"(focal adhesion)|go:"GO:0008104"(protein localization)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0009925"(basal plasma membrane)|go:"GO:0014905"(myoblast fusion involved in skeletal muscle regeneration)|go:"GO:0015485"(cholesterol binding)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0023026"(MHC class II protein complex binding)|go:"GO:0030890"(positive regulation of B cell proliferation)|go:"GO:0031623"(receptor internalization)|go:"GO:0031647"(regulation of protein stability)|go:"GO:0031982"(vesicle)|go:"GO:0034238"(macrophage fusion)|go:"GO:0035783"(CD4-positive, alpha-beta T cell costimulation)|go:"GO:0042289"(MHC class II protein binding)|go:"GO:0043128"(positive regulation of 1-phosphatidylinositol 4-kinase activity)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046718"(viral entry into host cell)|go:"GO:0046813"(receptor-mediated virion attachment to host cell)|go:"GO:0050731"(positive regulation of peptidyl-tyrosine phosphorylation)|go:"GO:0050861"(positive regulation of B cell receptor signaling pathway)|go:"GO:0050862"(positive regulation of T cell receptor signaling pathway)|go:"GO:0061462"(protein localization to lysosome)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070863"(positive regulation of protein exit from endoplasmic reticulum)|go:"GO:0071404"(cellular response to low-density lipoprotein particle stimulus)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0072675"(osteoclast fusion)|go:"GO:0097197"(tetraspanin-enriched microdomain)|go:"GO:1903911"(positive regulation of receptor clustering)|go:"GO:1904352"(positive regulation of protein catabolic process in the vacuole)|go:"GO:1905521"(regulation of macrophage migration)|go:"GO:1905676"(positive regulation of adaptive immune memory response)|go:"GO:1990459"(transferrin receptor binding)|go:"GO:2000553"(positive regulation of T-helper 2 cell cytokine production)|go:"GO:2000563"(positive regulation of CD4-positive, alpha-beta T cell proliferation)|go:"GO:2001190"(positive regulation of T cell activation via T cell receptor contact with antigen bound to MHC molecule on antigen presenting cell)|interpro:IPR000301(CD9/CD37/CD63 antigen)|interpro:IPR008952(Tetraspanin)|interpro:IPR018499|interpro:IPR018503|mint:P60033|rcsb pdb:1G8Q|rcsb pdb:1IV5|rcsb pdb:2AVZ|rcsb pdb:3X0E|rcsb pdb:5DFV|rcsb pdb:5DFW|rcsb pdb:5M2C|rcsb pdb:5M33|rcsb pdb:5M3D|rcsb pdb:5M3T|rcsb pdb:5M4R|rcsb pdb:5TCX|rcsb pdb:6EJG|rcsb pdb:6EJM|rcsb pdb:6EK2|rcsb pdb:6U9S|rcsb pdb:7JIC|reactome:R-HSA-198933|reactome:R-HSA-977606|refseq:NP_004347.1|refseq:NP_001284578.1 - - - figure legend:Fig.2A,Supp Table S5|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-testis)|taxid:9606(Homo sapiens) - 2020/03/24 2021/11/30 rogid:ZE4tXTFi7lUCcIbCL4KHzY3a6xM9606 rogid:LPDYYmkI2TtoCarkcBXuaibfB6A9606 rigid:/AFat0DrynAJ5ofEnoPSTThlxCE false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9BY14 uniprotkb:Q9UKY0 intact:EBI-12549378|ensembl:ENSP00000472769|uniprotkb:Q7L5R2|uniprotkb:Q9BPY7 intact:EBI-17783836|uniprotkb:A7U7M5|uniprotkb:Q9H311|uniprotkb:Q9H312|uniprotkb:Q9NTM4|ensembl:ENSP00000306900 psi-mi:tx101_human(display_long)|uniprotkb:TEX101(gene name)|psi-mi:TEX101(display_short)|uniprotkb:Cell surface receptor NYD-SP8(gene name synonym)|uniprotkb:SGRG(gene name synonym)|uniprotkb:Scleroderma-associated autoantigen(gene name synonym)|uniprotkb:Spermatogenesis-related gene protein(gene name synonym)|uniprotkb:UNQ867/PRO1884(orf name) psi-mi:prnd_human(display_long)|uniprotkb:PrPLP(gene name synonym)|uniprotkb:Prion protein 2(gene name synonym)|uniprotkb:UNQ1830/PRO3443(orf name)|uniprotkb:PRND(gene name)|psi-mi:PRND(display_short)|uniprotkb:DPL(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Schiza et al. (2018) imex:IM-28077|pubmed:30097533 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-25505061|imex:IM-28077-3 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000131126(gene)|ensembl:ENST00000598265(transcript)|go:"GO:0001669"(acrosomal vesicle)|go:"GO:0002080"(acrosomal membrane)|go:"GO:0005576"(extracellular region)|go:"GO:0005886"(plasma membrane)|go:"GO:0007339"(binding of sperm to zona pellucida)|go:"GO:0009566"(fertilization)|go:"GO:0030317"(flagellated sperm motility)|go:"GO:0044853"(plasma membrane raft)|go:"GO:0046658"(anchored component of plasma membrane)|go:"GO:1901317"(regulation of flagellated sperm motility)|interpro:IPR016054(Ly-6 antigen / uPA receptor -like)|rcsb pdb:7BPR|reactome:R-HSA-163125|refseq:NP_001123483.1|refseq:NP_113639.4 refseq:NP_036541.2|ensembl:ENSG00000171864(gene)|ensembl:ENST00000305817(transcript)|go:"GO:0005507"(copper ion binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005886"(plasma membrane)|go:"GO:0006878"(cellular copper ion homeostasis)|go:"GO:0007340"(acrosome reaction)|go:"GO:0031362"(anchored component of external side of plasma membrane)|go:"GO:0051260"(protein homooligomerization)|interpro:IPR021566|interpro:IPR022416|interpro:IPR036924|rcsb pdb:1LG4|reactome:R-HSA-163125 - - - figure legend:Fig.2A,Supp Table S5|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-testis)|taxid:9606(Homo sapiens) - 2020/03/24 2021/11/30 rogid:ZE4tXTFi7lUCcIbCL4KHzY3a6xM9606 rogid:p/L2mClefPuCaexWyimrRBRDdUE9606 rigid:/AFat0DrynAJ5ofEnoPSTThlxCE false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9BY14 uniprotkb:Q8NBM8 intact:EBI-12549378|ensembl:ENSP00000472769|uniprotkb:Q7L5R2|uniprotkb:Q9BPY7 intact:EBI-2827943|uniprotkb:Q8NF69|uniprotkb:Q9BWS3|uniprotkb:Q9BTE8|uniprotkb:Q8NCY5|uniprotkb:Q7Z4S2|ensembl:ENSP00000274569 psi-mi:tx101_human(display_long)|uniprotkb:TEX101(gene name)|psi-mi:TEX101(display_short)|uniprotkb:Cell surface receptor NYD-SP8(gene name synonym)|uniprotkb:SGRG(gene name synonym)|uniprotkb:Scleroderma-associated autoantigen(gene name synonym)|uniprotkb:Spermatogenesis-related gene protein(gene name synonym)|uniprotkb:UNQ867/PRO1884(orf name) psi-mi:pcyxl_human(display_long)|uniprotkb:PCYOX1L(gene name)|psi-mi:PCYOX1L(display_short)|uniprotkb:PSEC0105(orf name) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Schiza et al. (2018) imex:IM-28077|pubmed:30097533 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-25505061|imex:IM-28077-3 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000131126(gene)|ensembl:ENST00000598265(transcript)|go:"GO:0001669"(acrosomal vesicle)|go:"GO:0002080"(acrosomal membrane)|go:"GO:0005576"(extracellular region)|go:"GO:0005886"(plasma membrane)|go:"GO:0007339"(binding of sperm to zona pellucida)|go:"GO:0009566"(fertilization)|go:"GO:0030317"(flagellated sperm motility)|go:"GO:0044853"(plasma membrane raft)|go:"GO:0046658"(anchored component of plasma membrane)|go:"GO:1901317"(regulation of flagellated sperm motility)|interpro:IPR016054(Ly-6 antigen / uPA receptor -like)|rcsb pdb:7BPR|reactome:R-HSA-163125|refseq:NP_001123483.1|refseq:NP_113639.4 refseq:NP_076933.3|ensembl:ENSG00000145882(gene)|ensembl:ENST00000274569(transcript)|go:"GO:0001735"(prenylcysteine oxidase activity)|go:"GO:0005576"(extracellular region)|go:"GO:0016020"(membrane)|go:"GO:0030327"(prenylated protein catabolic process)|go:"GO:0031093"(platelet alpha granule lumen)|interpro:IPR010795(Prenylcysteine lyase)|interpro:IPR017046(Prenylcysteine oxidase)|interpro:IPR036188|reactome:R-HSA-114608|go:"GO:0030328"(prenylcysteine catabolic process)|refseq:NP_001287983.1|refseq:NP_001287986.1 - - - figure legend:Fig.2A,Supp Table S5|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-testis)|taxid:9606(Homo sapiens) - 2020/03/24 2021/11/30 rogid:ZE4tXTFi7lUCcIbCL4KHzY3a6xM9606 rogid:hpBRATNd7KeKAC6ojQzl5AUnpHM9606 rigid:/AFat0DrynAJ5ofEnoPSTThlxCE false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9BY14 uniprotkb:Q10713 intact:EBI-12549378|ensembl:ENSP00000472769|uniprotkb:Q7L5R2|uniprotkb:Q9BPY7 intact:EBI-2514696|ensembl:ENSP00000360782|uniprotkb:Q8N513|uniprotkb:Q16639|uniprotkb:Q5SXM9|uniprotkb:B4DKL3|uniprotkb:E7ET61 psi-mi:tx101_human(display_long)|uniprotkb:TEX101(gene name)|psi-mi:TEX101(display_short)|uniprotkb:Cell surface receptor NYD-SP8(gene name synonym)|uniprotkb:SGRG(gene name synonym)|uniprotkb:Scleroderma-associated autoantigen(gene name synonym)|uniprotkb:Spermatogenesis-related gene protein(gene name synonym)|uniprotkb:UNQ867/PRO1884(orf name) psi-mi:mppa_human(display_long)|uniprotkb:PMPCA(gene name)|psi-mi:PMPCA(display_short)|uniprotkb:INPP5E(gene name synonym)|uniprotkb:KIAA0123(gene name synonym)|uniprotkb:MPPA(gene name synonym)|uniprotkb:Alpha-MPP(gene name synonym)|uniprotkb:P-55(gene name synonym)|uniprotkb:Inactive zinc metalloprotease alpha(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Schiza et al. (2018) imex:IM-28077|pubmed:30097533 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-25505061|imex:IM-28077-3 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000131126(gene)|ensembl:ENST00000598265(transcript)|go:"GO:0001669"(acrosomal vesicle)|go:"GO:0002080"(acrosomal membrane)|go:"GO:0005576"(extracellular region)|go:"GO:0005886"(plasma membrane)|go:"GO:0007339"(binding of sperm to zona pellucida)|go:"GO:0009566"(fertilization)|go:"GO:0030317"(flagellated sperm motility)|go:"GO:0044853"(plasma membrane raft)|go:"GO:0046658"(anchored component of plasma membrane)|go:"GO:1901317"(regulation of flagellated sperm motility)|interpro:IPR016054(Ly-6 antigen / uPA receptor -like)|rcsb pdb:7BPR|reactome:R-HSA-163125|refseq:NP_001123483.1|refseq:NP_113639.4 refseq:NP_001269875.1|ensembl:ENSG00000165688(gene)|ensembl:ENST00000371717(transcript)|go:"GO:0005615"(extracellular space)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0006627"(protein processing involved in protein targeting to mitochondrion)|go:"GO:0046872"(metal ion binding)|interpro:IPR001431(Peptidase M16, zinc-binding site)|interpro:IPR007863(Peptidase M16, C-terminal)|interpro:IPR011249(Metalloenzyme, LuxS/M16 peptidase-like, metal-binding)|interpro:IPR011765(Peptidase M16, N-terminal)|reactome:R-HSA-1268020|reactome:R-HSA-8949664|interpro:IPR037715|refseq:NP_001269873.1|refseq:NP_055975.1 - - - figure legend:Fig.2A,Supp Table S5|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-testis)|taxid:9606(Homo sapiens) - 2020/03/24 2021/11/30 rogid:ZE4tXTFi7lUCcIbCL4KHzY3a6xM9606 rogid:Kqz7qIyX2eUOcnNrfIsSPjc4Isw9606 rigid:/AFat0DrynAJ5ofEnoPSTThlxCE false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9BY14 uniprotkb:Q9UI14 intact:EBI-12549378|ensembl:ENSP00000472769|uniprotkb:Q7L5R2|uniprotkb:Q9BPY7 intact:EBI-712367|ensembl:ENSP00000222008|uniprotkb:Q7Z4Y2|uniprotkb:Q9Y3R1 psi-mi:tx101_human(display_long)|uniprotkb:TEX101(gene name)|psi-mi:TEX101(display_short)|uniprotkb:Cell surface receptor NYD-SP8(gene name synonym)|uniprotkb:SGRG(gene name synonym)|uniprotkb:Scleroderma-associated autoantigen(gene name synonym)|uniprotkb:Spermatogenesis-related gene protein(gene name synonym)|uniprotkb:UNQ867/PRO1884(orf name) psi-mi:praf1_human(display_long)|uniprotkb:PRA1 family protein 1(gene name synonym)|uniprotkb:RABAC1(gene name)|psi-mi:RABAC1(display_short)|uniprotkb:PRA1(gene name synonym)|uniprotkb:PRAF1(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Schiza et al. (2018) imex:IM-28077|pubmed:30097533 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-25505061|imex:IM-28077-3 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000131126(gene)|ensembl:ENST00000598265(transcript)|go:"GO:0001669"(acrosomal vesicle)|go:"GO:0002080"(acrosomal membrane)|go:"GO:0005576"(extracellular region)|go:"GO:0005886"(plasma membrane)|go:"GO:0007339"(binding of sperm to zona pellucida)|go:"GO:0009566"(fertilization)|go:"GO:0030317"(flagellated sperm motility)|go:"GO:0044853"(plasma membrane raft)|go:"GO:0046658"(anchored component of plasma membrane)|go:"GO:1901317"(regulation of flagellated sperm motility)|interpro:IPR016054(Ly-6 antigen / uPA receptor -like)|rcsb pdb:7BPR|reactome:R-HSA-163125|refseq:NP_001123483.1|refseq:NP_113639.4 refseq:NP_006414.2|ensembl:ENSG00000105404(gene)|ensembl:ENST00000222008(transcript)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0070064"(proline-rich region binding)|interpro:IPR004895(Prenylated rab acceptor PRA1)|mint:Q9UI14 - - - figure legend:Fig.2A,Supp Table S5|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-testis)|taxid:9606(Homo sapiens) - 2020/03/24 2021/11/30 rogid:ZE4tXTFi7lUCcIbCL4KHzY3a6xM9606 rogid:WS2rUY7yXRbR7pqWgfUCbnEiDbg9606 rigid:/AFat0DrynAJ5ofEnoPSTThlxCE false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9BY14 uniprotkb:P61019 intact:EBI-12549378|ensembl:ENSP00000472769|uniprotkb:Q7L5R2|uniprotkb:Q9BPY7 intact:EBI-752037|uniprotkb:P08886|uniprotkb:B2R5W8|uniprotkb:B4DMQ5|ensembl:ENSP00000262646 psi-mi:tx101_human(display_long)|uniprotkb:TEX101(gene name)|psi-mi:TEX101(display_short)|uniprotkb:Cell surface receptor NYD-SP8(gene name synonym)|uniprotkb:SGRG(gene name synonym)|uniprotkb:Scleroderma-associated autoantigen(gene name synonym)|uniprotkb:Spermatogenesis-related gene protein(gene name synonym)|uniprotkb:UNQ867/PRO1884(orf name) psi-mi:rab2a_human(display_long)|uniprotkb:RAB2A(gene name)|psi-mi:RAB2A(display_short)|uniprotkb:RAB2(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Schiza et al. (2018) imex:IM-28077|pubmed:30097533 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-25505061|imex:IM-28077-3 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000131126(gene)|ensembl:ENST00000598265(transcript)|go:"GO:0001669"(acrosomal vesicle)|go:"GO:0002080"(acrosomal membrane)|go:"GO:0005576"(extracellular region)|go:"GO:0005886"(plasma membrane)|go:"GO:0007339"(binding of sperm to zona pellucida)|go:"GO:0009566"(fertilization)|go:"GO:0030317"(flagellated sperm motility)|go:"GO:0044853"(plasma membrane raft)|go:"GO:0046658"(anchored component of plasma membrane)|go:"GO:1901317"(regulation of flagellated sperm motility)|interpro:IPR016054(Ly-6 antigen / uPA receptor -like)|rcsb pdb:7BPR|reactome:R-HSA-163125|refseq:NP_001123483.1|refseq:NP_113639.4 refseq:NP_002856.1|refseq:NP_001229573.1|dip:DIP-316N|ensembl:ENSG00000104388(gene)|ensembl:ENST00000262646(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0007030"(Golgi organization)|go:"GO:0015031"(protein transport)|go:"GO:0019003"(GDP binding)|go:"GO:0033116"(endoplasmic reticulum-Golgi intermediate compartment membrane)|go:"GO:0042470"(melanosome)|go:"GO:0070062"(extracellular exosome)|interpro:IPR001806(Ras GTPase)|interpro:IPR005225(Small GTP-binding protein)|interpro:IPR027417|rcsb pdb:1Z0A|reactome:R-HSA-162658|reactome:R-HSA-8873719 - - - figure legend:Fig.2A,Supp Table S5|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-testis)|taxid:9606(Homo sapiens) - 2020/03/24 2021/11/30 rogid:ZE4tXTFi7lUCcIbCL4KHzY3a6xM9606 rogid:MyG011KOkAtsvE2hU/fs21CEe/M9606 rigid:/AFat0DrynAJ5ofEnoPSTThlxCE false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9BY14 uniprotkb:Q13148 intact:EBI-12549378|ensembl:ENSP00000472769|uniprotkb:Q7L5R2|uniprotkb:Q9BPY7 intact:EBI-372899|uniprotkb:Q6FI92|uniprotkb:E2PU12|uniprotkb:Q96DJ0|intact:EBI-2821405|uniprotkb:A4GUK4|uniprotkb:A4GUK5|uniprotkb:A4GUK6|uniprotkb:B2R629|uniprotkb:Q53H27|uniprotkb:B4DJ45|ensembl:ENSP00000240185|ensembl:ENSP00000491203 psi-mi:tx101_human(display_long)|uniprotkb:TEX101(gene name)|psi-mi:TEX101(display_short)|uniprotkb:Cell surface receptor NYD-SP8(gene name synonym)|uniprotkb:SGRG(gene name synonym)|uniprotkb:Scleroderma-associated autoantigen(gene name synonym)|uniprotkb:Spermatogenesis-related gene protein(gene name synonym)|uniprotkb:UNQ867/PRO1884(orf name) psi-mi:tadbp_human(display_long)|uniprotkb:TARDBP(gene name)|psi-mi:TARDBP(display_short)|uniprotkb:TDP43(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Schiza et al. (2018) imex:IM-28077|pubmed:30097533 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-25505061|imex:IM-28077-3 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000131126(gene)|ensembl:ENST00000598265(transcript)|go:"GO:0001669"(acrosomal vesicle)|go:"GO:0002080"(acrosomal membrane)|go:"GO:0005576"(extracellular region)|go:"GO:0005886"(plasma membrane)|go:"GO:0007339"(binding of sperm to zona pellucida)|go:"GO:0009566"(fertilization)|go:"GO:0030317"(flagellated sperm motility)|go:"GO:0044853"(plasma membrane raft)|go:"GO:0046658"(anchored component of plasma membrane)|go:"GO:1901317"(regulation of flagellated sperm motility)|interpro:IPR016054(Ly-6 antigen / uPA receptor -like)|rcsb pdb:7BPR|reactome:R-HSA-163125|refseq:NP_001123483.1|refseq:NP_113639.4 refseq:NP_031401.1|ensembl:ENSG00000120948(gene)|ensembl:ENST00000240185(transcript)|ensembl:ENST00000639083(transcript)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0001933"(negative regulation of protein phosphorylation)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0003730"(mRNA 3'-UTR binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005726"(perichromatin fibrils)|go:"GO:0006397"(mRNA processing)|go:"GO:0008380"(RNA splicing)|go:"GO:0032024"(positive regulation of insulin secretion)|go:"GO:0034976"(response to endoplasmic reticulum stress)|go:"GO:0035061"(interchromatin granule)|go:"GO:0042307"(positive regulation of protein import into nucleus)|go:"GO:0042752"(regulation of circadian rhythm)|go:"GO:0042802"(identical protein binding)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0043922"(negative regulation by host of viral transcription)|go:"GO:0048511"(rhythmic process)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0061158"(3'-UTR-mediated mRNA destabilization)|go:"GO:0070935"(3'-UTR-mediated mRNA stabilization)|go:"GO:0071765"(nuclear inner membrane organization)|go:"GO:0097157"(pre-mRNA intronic binding)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR035979|interpro:IPR041105|mint:Q13148|rcsb pdb:1WF0|rcsb pdb:2CQG|rcsb pdb:2N2C|rcsb pdb:2N3X|rcsb pdb:2N4G|rcsb pdb:2N4H|rcsb pdb:2N4P|rcsb pdb:4BS2|rcsb pdb:4IUF|rcsb pdb:4Y00|rcsb pdb:4Y0F|rcsb pdb:5MDI|rcsb pdb:5MRG|rcsb pdb:5W50|rcsb pdb:5W52|rcsb pdb:5W7V|rcsb pdb:5WHN|rcsb pdb:5WHP|rcsb pdb:5WIA|rcsb pdb:5WIQ|rcsb pdb:5WKB|rcsb pdb:5WKD|rcsb pdb:5X4F|rcsb pdb:6B1G|rcsb pdb:6CF4|rcsb pdb:6CFH|rcsb pdb:6N37|rcsb pdb:6N3A|rcsb pdb:6N3B|rcsb pdb:6N3C|rcsb pdb:6T4B|rcsb pdb:7KWZ|go:"GO:0010468"(regulation of gene expression)|go:"GO:0010494"(cytoplasmic stress granule)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0016607"(nuclear speck)|go:"GO:0031647"(regulation of protein stability)|refseq:XP_016856352.1|refseq:XP_016856353.1|refseq:XP_016856354.1|refseq:XP_016856355.1|refseq:XP_016856356.1|refseq:XP_016856357.1|dip:DIP-31167N - - - figure legend:Fig.2A,Supp Table S5|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-testis)|taxid:9606(Homo sapiens) - 2020/03/24 2021/11/30 rogid:ZE4tXTFi7lUCcIbCL4KHzY3a6xM9606 rogid:KG5C6KnWiKeFQLYbHcfr9a11Ro49606 rigid:/AFat0DrynAJ5ofEnoPSTThlxCE false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9BY14 uniprotkb:Q9ULP0 intact:EBI-12549378|ensembl:ENSP00000472769|uniprotkb:Q7L5R2|uniprotkb:Q9BPY7 intact:EBI-10323810|uniprotkb:Q96PL9|uniprotkb:Q9GZX0|uniprotkb:H7C600|uniprotkb:B3KNU2|uniprotkb:Q6ZNE7|uniprotkb:Q9GZN3|uniprotkb:Q9GZM1|uniprotkb:Q6ZTI7|uniprotkb:B4DK66|uniprotkb:B4DSW5|ensembl:ENSP00000457659 psi-mi:tx101_human(display_long)|uniprotkb:TEX101(gene name)|psi-mi:TEX101(display_short)|uniprotkb:Cell surface receptor NYD-SP8(gene name synonym)|uniprotkb:SGRG(gene name synonym)|uniprotkb:Scleroderma-associated autoantigen(gene name synonym)|uniprotkb:Spermatogenesis-related gene protein(gene name synonym)|uniprotkb:UNQ867/PRO1884(orf name) psi-mi:ndrg4_human(display_long)|uniprotkb:NDRG4(gene name)|psi-mi:NDRG4(display_short)|uniprotkb:BDM1(gene name synonym)|uniprotkb:Brain development-related molecule 1(gene name synonym)|uniprotkb:KIAA1180(gene name synonym)|uniprotkb:N-myc downstream-regulated gene 4 protein(gene name synonym)|uniprotkb:Vascular smooth muscle cell-associated protein 8(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Schiza et al. (2018) imex:IM-28077|pubmed:30097533 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-25505061|imex:IM-28077-3 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000131126(gene)|ensembl:ENST00000598265(transcript)|go:"GO:0001669"(acrosomal vesicle)|go:"GO:0002080"(acrosomal membrane)|go:"GO:0005576"(extracellular region)|go:"GO:0005886"(plasma membrane)|go:"GO:0007339"(binding of sperm to zona pellucida)|go:"GO:0009566"(fertilization)|go:"GO:0030317"(flagellated sperm motility)|go:"GO:0044853"(plasma membrane raft)|go:"GO:0046658"(anchored component of plasma membrane)|go:"GO:1901317"(regulation of flagellated sperm motility)|interpro:IPR016054(Ly-6 antigen / uPA receptor -like)|rcsb pdb:7BPR|reactome:R-HSA-163125|refseq:NP_001123483.1|refseq:NP_113639.4 refseq:NP_001123959.1|refseq:NP_001229762.1|refseq:NP_001229763.1|refseq:NP_001229764.1|refseq:NP_001229765.1|refseq:NP_065198.1|refseq:NP_075061.1|ensembl:ENSG00000103034(gene)|ensembl:ENST00000570248(transcript)|go:"GO:0001947"(heart looping)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005829"(cytosol)|go:"GO:0007165"(signal transduction)|go:"GO:0007420"(brain development)|go:"GO:0008542"(visual learning)|go:"GO:0010642"(negative regulation of platelet-derived growth factor receptor signaling pathway)|go:"GO:0010976"(positive regulation of neuron projection development)|go:"GO:0014912"(negative regulation of smooth muscle cell migration)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0030154"(cell differentiation)|go:"GO:0031253"(cell projection membrane)|go:"GO:0035050"(embryonic heart tube development)|go:"GO:0048278"(vesicle docking)|go:"GO:0048662"(negative regulation of smooth muscle cell proliferation)|go:"GO:0060038"(cardiac muscle cell proliferation)|go:"GO:0060973"(cell migration involved in heart development)|go:"GO:0070374"(positive regulation of ERK1 and ERK2 cascade)|go:"GO:2001135"(regulation of endocytic recycling)|interpro:IPR004142(Ndr)|interpro:IPR029058|interpro:IPR030695|mint:Q9ULP0|refseq:XP_016879079.1 - - - figure legend:Fig.2A,Supp Table S5|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-testis)|taxid:9606(Homo sapiens) - 2020/03/24 2021/11/30 rogid:ZE4tXTFi7lUCcIbCL4KHzY3a6xM9606 rogid:66xDAShV6u8TldB/nbR5ru0h7A49606 rigid:/AFat0DrynAJ5ofEnoPSTThlxCE false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9BY14 uniprotkb:P0C0L4 intact:EBI-12549378|ensembl:ENSP00000472769|uniprotkb:Q7L5R2|uniprotkb:Q9BPY7 intact:EBI-1223619|uniprotkb:P01028|uniprotkb:P78445|uniprotkb:Q13160|uniprotkb:Q13906|uniprotkb:Q14033|uniprotkb:Q14835|uniprotkb:Q5JQM8|uniprotkb:Q9NPK5|uniprotkb:Q9UIP5|uniprotkb:B0QZR6|uniprotkb:A6H8M8|uniprotkb:A6NHJ5|uniprotkb:A7E2V2|uniprotkb:B0V2C8|uniprotkb:B2RUT6|uniprotkb:B7ZVZ6|uniprotkb:Q4LE82|uniprotkb:Q5JNX2|uniprotkb:Q6P4R1|uniprotkb:Q6U2E5|uniprotkb:Q6U2E8|uniprotkb:Q6U2F0|uniprotkb:Q6U2F3|uniprotkb:Q6U2F4|uniprotkb:Q6U2F6|uniprotkb:Q6U2F8|uniprotkb:Q6U2G0|uniprotkb:Q96EG2|uniprotkb:Q96SA8|ensembl:ENSP00000388662|ensembl:ENSP00000396688|ensembl:ENSP00000372815 psi-mi:tx101_human(display_long)|uniprotkb:TEX101(gene name)|psi-mi:TEX101(display_short)|uniprotkb:Cell surface receptor NYD-SP8(gene name synonym)|uniprotkb:SGRG(gene name synonym)|uniprotkb:Scleroderma-associated autoantigen(gene name synonym)|uniprotkb:Spermatogenesis-related gene protein(gene name synonym)|uniprotkb:UNQ867/PRO1884(orf name) psi-mi:co4a_human(display_long)|uniprotkb:C4A(gene name)|psi-mi:C4A(display_short)|uniprotkb:CO4(gene name synonym)|uniprotkb:CPAMD2(gene name synonym)|uniprotkb:Acidic complement C4(gene name synonym)|uniprotkb:C3 and PZP-like alpha-2-macroglobulin domain-containing protein 2(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Schiza et al. (2018) imex:IM-28077|pubmed:30097533 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-25505061|imex:IM-28077-3 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000131126(gene)|ensembl:ENST00000598265(transcript)|go:"GO:0001669"(acrosomal vesicle)|go:"GO:0002080"(acrosomal membrane)|go:"GO:0005576"(extracellular region)|go:"GO:0005886"(plasma membrane)|go:"GO:0007339"(binding of sperm to zona pellucida)|go:"GO:0009566"(fertilization)|go:"GO:0030317"(flagellated sperm motility)|go:"GO:0044853"(plasma membrane raft)|go:"GO:0046658"(anchored component of plasma membrane)|go:"GO:1901317"(regulation of flagellated sperm motility)|interpro:IPR016054(Ly-6 antigen / uPA receptor -like)|rcsb pdb:7BPR|reactome:R-HSA-163125|refseq:NP_001123483.1|refseq:NP_113639.4 refseq:NP_009224.2|refseq:NP_001002029.3|refseq:NP_001239133.1|ensembl:ENSG00000206340(gene)|ensembl:ENSG00000227746(gene)|ensembl:ENSG00000244731(gene)|ensembl:ENST00000383325(transcript)|ensembl:ENST00000421274(transcript)|ensembl:ENST00000428956(transcript)|go:"GO:0001849"(complement component C1q complex binding)|go:"GO:0004866"(endopeptidase inhibitor activity)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0005788"(endoplasmic reticulum lumen)|go:"GO:0005886"(plasma membrane)|go:"GO:0006954"(inflammatory response)|go:"GO:0006956"(complement activation)|go:"GO:0006958"(complement activation, classical pathway)|go:"GO:0030424"(axon)|go:"GO:0030425"(dendrite)|go:"GO:0043025"(neuronal cell body)|go:"GO:0045087"(innate immune response)|go:"GO:0045202"(synapse)|go:"GO:0070062"(extracellular exosome)|go:"GO:0072562"(blood microparticle)|go:"GO:2000427"(positive regulation of apoptotic cell clearance)|interpro:IPR000020(Anaphylatoxin/fibulin)|interpro:IPR001134(Netrin, C-terminal)|interpro:IPR001599(Alpha-2-macroglobulin)|interpro:IPR001840(Complement C3a/C4a/C5a anaphylatoxin)|interpro:IPR002890(Alpha-2-macroglobulin, N-terminal)|interpro:IPR008930(Terpenoid cylases/protein prenyltransferase alpha-alpha toroid)|interpro:IPR008993(TIMP-like, OB-fold)|interpro:IPR009048(Alpha-macroglobulin, receptor-binding)|interpro:IPR011625(Alpha-2-macroglobulin, N-terminal 2)|interpro:IPR011626(A-macroglobulin complement component)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR018081|interpro:IPR018933|interpro:IPR019742|interpro:IPR036595|interpro:IPR037569|interpro:IPR040839|interpro:IPR041555|rcsb pdb:1HZF|rcsb pdb:4FXG|rcsb pdb:4FXK|rcsb pdb:4XAM|rcsb pdb:5JPM|rcsb pdb:5JPN|rcsb pdb:5JTW|reactome:R-HSA-166663|reactome:R-HSA-174577|reactome:R-HSA-381426|reactome:R-HSA-8957275|reactome:R-HSA-977606 - - - figure legend:Fig.2A,Supp Table S5|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-testis)|taxid:9606(Homo sapiens) - 2020/03/24 2021/11/30 rogid:ZE4tXTFi7lUCcIbCL4KHzY3a6xM9606 rogid:nLlIFlW5RCngnXASkYPGREjA/1E9606 rigid:/AFat0DrynAJ5ofEnoPSTThlxCE false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9BY14 uniprotkb:P27824 intact:EBI-12549378|ensembl:ENSP00000472769|uniprotkb:Q7L5R2|uniprotkb:Q9BPY7 intact:EBI-355947|uniprotkb:D3DWQ3|uniprotkb:B2R5V8|ensembl:ENSP00000421434|ensembl:ENSP00000421813|ensembl:ENSP00000424063|ensembl:ENSP00000424745|ensembl:ENSP00000491760|ensembl:ENSP00000492372|ensembl:ENSP00000492868|ensembl:ENSP00000505013|ensembl:ENSP00000505202|ensembl:ENSP00000505526|ensembl:ENSP00000505960|ensembl:ENSP00000506003|ensembl:ENSP00000506021|ensembl:ENSP00000506061|ensembl:ENSP00000506078|ensembl:ENSP00000506509|ensembl:ENSP00000506568|ensembl:ENSP00000506583|ensembl:ENSP00000247461|ensembl:ENSP00000391646|intact:EBI-9513217|uniprotkb:B4DGP8|uniprotkb:B4E2T8|uniprotkb:D6R9K3 psi-mi:tx101_human(display_long)|uniprotkb:TEX101(gene name)|psi-mi:TEX101(display_short)|uniprotkb:Cell surface receptor NYD-SP8(gene name synonym)|uniprotkb:SGRG(gene name synonym)|uniprotkb:Scleroderma-associated autoantigen(gene name synonym)|uniprotkb:Spermatogenesis-related gene protein(gene name synonym)|uniprotkb:UNQ867/PRO1884(orf name) psi-mi:calx_human(display_long)|uniprotkb:CANX(gene name)|psi-mi:CANX(display_short)|uniprotkb:Major histocompatibility complex class I antigen-binding protein p88(gene name synonym)|uniprotkb:p90(gene name synonym)|uniprotkb:IP90(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Schiza et al. (2018) imex:IM-28077|pubmed:30097533 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-25505061|imex:IM-28077-3 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000131126(gene)|ensembl:ENST00000598265(transcript)|go:"GO:0001669"(acrosomal vesicle)|go:"GO:0002080"(acrosomal membrane)|go:"GO:0005576"(extracellular region)|go:"GO:0005886"(plasma membrane)|go:"GO:0007339"(binding of sperm to zona pellucida)|go:"GO:0009566"(fertilization)|go:"GO:0030317"(flagellated sperm motility)|go:"GO:0044853"(plasma membrane raft)|go:"GO:0046658"(anchored component of plasma membrane)|go:"GO:1901317"(regulation of flagellated sperm motility)|interpro:IPR016054(Ly-6 antigen / uPA receptor -like)|rcsb pdb:7BPR|reactome:R-HSA-163125|refseq:NP_001123483.1|refseq:NP_113639.4 refseq:NP_001019820.1|refseq:NP_001737.1|refseq:XP_011532967.1|go:"GO:0099059"(integral component of presynaptic active zone membrane)|interpro:IPR001580(Calreticulin/calnexin)|interpro:IPR009033(Calreticulin/calnexin, P)|interpro:IPR013320(Concanavalin A-like lectin/glucanase, subgroup)|interpro:IPR018124|mint:P27824|reactome:R-HSA-168316|reactome:R-HSA-2132295|reactome:R-HSA-8984722|reactome:R-HSA-901042|reactome:R-HSA-9020956|reactome:R-HSA-9683686|reactome:R-HSA-9694548|reactome:R-HSA-983170|ensembl:ENST00000452673(transcript)|ensembl:ENST00000502296(transcript)|ensembl:ENST00000504734(transcript)|ensembl:ENST00000509563(transcript)|ensembl:ENST00000513246(transcript)|ensembl:ENST00000638425(transcript)|ensembl:ENST00000638706(transcript)|ensembl:ENST00000639938(transcript)|ensembl:ENST00000680013(transcript)|ensembl:ENST00000680042(transcript)|ensembl:ENST00000680092(transcript)|ensembl:ENST00000680618(transcript)|ensembl:ENST00000681072(transcript)|ensembl:ENST00000681168(transcript)|ensembl:ENST00000681476(transcript)|ensembl:ENST00000681674(transcript)|ensembl:ENST00000681712(transcript)|ensembl:ENST00000681733(transcript)|ensembl:ENST00000681903(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005788"(endoplasmic reticulum lumen)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005790"(smooth endoplasmic reticulum)|ensembl:ENST00000247461(transcript)|go:"GO:0005840"(ribosome)|go:"GO:0006457"(protein folding)|go:"GO:0007568"(aging)|go:"GO:0009306"(protein secretion)|go:"GO:0016020"(membrane)|go:"GO:0019082"(viral protein processing)|go:"GO:0030246"(carbohydrate binding)|go:"GO:0030424"(axon)|go:"GO:0030968"(endoplasmic reticulum unfolded protein response)|go:"GO:0032839"(dendrite cytoplasm)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034185"(apolipoprotein binding)|go:"GO:0034975"(protein folding in endoplasmic reticulum)|go:"GO:0035255"(ionotropic glutamate receptor binding)|go:"GO:0042470"(melanosome)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043197"(dendritic spine)|go:"GO:0044233"(mitochondria-associated endoplasmic reticulum membrane)|go:"GO:0044322"(endoplasmic reticulum quality control compartment)|go:"GO:0048488"(synaptic vesicle endocytosis)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071556"(integral component of lumenal side of endoplasmic reticulum membrane)|go:"GO:0072583"(clathrin-dependent endocytosis)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099055"(integral component of postsynaptic membrane)|go:"GO:0005791"(rough endoplasmic reticulum)|ensembl:ENSG00000127022(gene)|ensembl:ENSG00000283777(gene)|dip:DIP-457N - - - figure legend:Fig.2A,Supp Table S5|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-testis)|taxid:9606(Homo sapiens) - 2020/03/24 2021/11/30 rogid:ZE4tXTFi7lUCcIbCL4KHzY3a6xM9606 rogid:Vy9HZjl19IXifyFpueW0LXi9ENk9606 rigid:/AFat0DrynAJ5ofEnoPSTThlxCE false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9BY14 uniprotkb:P46940 intact:EBI-12549378|ensembl:ENSP00000472769|uniprotkb:Q7L5R2|uniprotkb:Q9BPY7 intact:EBI-297509|ensembl:ENSP00000268182|uniprotkb:A7MBM3 psi-mi:tx101_human(display_long)|uniprotkb:TEX101(gene name)|psi-mi:TEX101(display_short)|uniprotkb:Cell surface receptor NYD-SP8(gene name synonym)|uniprotkb:SGRG(gene name synonym)|uniprotkb:Scleroderma-associated autoantigen(gene name synonym)|uniprotkb:Spermatogenesis-related gene protein(gene name synonym)|uniprotkb:UNQ867/PRO1884(orf name) psi-mi:iqga1_human(display_long)|uniprotkb:IQGAP1(gene name)|psi-mi:IQGAP1(display_short)|uniprotkb:KIAA0051(gene name synonym)|uniprotkb:p195(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Schiza et al. (2018) imex:IM-28077|pubmed:30097533 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-25505061|imex:IM-28077-3 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000131126(gene)|ensembl:ENST00000598265(transcript)|go:"GO:0001669"(acrosomal vesicle)|go:"GO:0002080"(acrosomal membrane)|go:"GO:0005576"(extracellular region)|go:"GO:0005886"(plasma membrane)|go:"GO:0007339"(binding of sperm to zona pellucida)|go:"GO:0009566"(fertilization)|go:"GO:0030317"(flagellated sperm motility)|go:"GO:0044853"(plasma membrane raft)|go:"GO:0046658"(anchored component of plasma membrane)|go:"GO:1901317"(regulation of flagellated sperm motility)|interpro:IPR016054(Ly-6 antigen / uPA receptor -like)|rcsb pdb:7BPR|reactome:R-HSA-163125|refseq:NP_001123483.1|refseq:NP_113639.4 ensembl:ENSG00000140575(gene)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005547"(phosphatidylinositol-3,4,5-trisphosphate binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005874"(microtubule)|go:"GO:0005884"(actin filament)|go:"GO:0005886"(plasma membrane)|ensembl:ENST00000268182(transcript)|go:"GO:0001726"(ruffle)|go:"GO:0005925"(focal adhesion)|go:"GO:0007165"(signal transduction)|go:"GO:0007173"(epidermal growth factor receptor signaling pathway)|go:"GO:0005078"(MAP-kinase scaffold activity)|go:"GO:0005095"(GTPase inhibitor activity)|go:"GO:0007346"(regulation of mitotic cell cycle)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0016477"(cell migration)|go:"GO:0019901"(protein kinase binding)|go:"GO:0019903"(protein phosphatase binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0005509"(calcium ion binding)|go:"GO:0030424"(axon)|go:"GO:0030426"(growth cone)|go:"GO:0030496"(midbody)|go:"GO:0031234"(extrinsic component of cytoplasmic side of plasma membrane)|go:"GO:0031267"(small GTPase binding)|go:"GO:0032956"(regulation of actin cytoskeleton organization)|go:"GO:0032991"(protein-containing complex)|go:"GO:0036057"(slit diaphragm)|go:"GO:0036464"(cytoplasmic ribonucleoprotein granule)|go:"GO:0043005"(neuron projection)|go:"GO:0043087"(regulation of GTPase activity)|go:"GO:0043406"(positive regulation of MAP kinase activity)|go:"GO:0043410"(positive regulation of MAPK cascade)|go:"GO:0043539"(protein serine/threonine kinase activator activity)|go:"GO:0044548"(S100 protein binding)|go:"GO:0045121"(membrane raft)|go:"GO:0045296"(cadherin binding)|go:"GO:0045860"(positive regulation of protein kinase activity)|go:"GO:0051015"(actin filament binding)|go:"GO:0051019"(mitogen-activated protein kinase binding)|go:"GO:0051894"(positive regulation of focal adhesion assembly)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071277"(cellular response to calcium ion)|go:"GO:0071364"(cellular response to epidermal growth factor stimulus)|go:"GO:0072015"(glomerular visceral epithelial cell development)|go:"GO:1900006"(positive regulation of dendrite development)|go:"GO:1900086"(positive regulation of peptidyl-tyrosine autophosphorylation)|go:"GO:1903829"(positive regulation of protein localization)|go:"GO:1904754"(positive regulation of vascular associated smooth muscle cell migration)|go:"GO:1990138"(neuron projection extension)|go:"GO:1990776"(response to angiotensin)|interpro:IPR000048(IQ calmodulin-binding region)|go:"GO:0030667"(secretory granule membrane)|interpro:IPR000593(RasGAP protein, C-terminal)|interpro:IPR001202(WW/Rsp5/WWP)|interpro:IPR001715(Calponin-like actin-binding)|interpro:IPR001936(Ras GTPase-activating protein)|interpro:IPR008936(Rho GTPase activation protein)|interpro:IPR023152|interpro:IPR027417|interpro:IPR036872|mint:P46940|rcsb pdb:1X0H|rcsb pdb:2RR8|rcsb pdb:3FAY|rcsb pdb:3I6X|rcsb pdb:5L0O|reactome:R-HSA-373753|reactome:R-HSA-381676|reactome:R-HSA-5626467|reactome:R-HSA-5674135|reactome:R-HSA-6798695|reactome:R-HSA-6802946|reactome:R-HSA-6802948|reactome:R-HSA-6802952|reactome:R-HSA-6802955|reactome:R-HSA-8980692|reactome:R-HSA-9013106|reactome:R-HSA-9013148|reactome:R-HSA-9013149|reactome:R-HSA-9013404|reactome:R-HSA-9013406|reactome:R-HSA-9013420|reactome:R-HSA-9013424|reactome:R-HSA-9649948|reactome:R-HSA-9656223|refseq:NP_003861.1|dip:DIP-32597N - - - figure legend:Fig.2A,Supp Table S5|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-testis)|taxid:9606(Homo sapiens) - 2020/03/24 2021/11/30 rogid:ZE4tXTFi7lUCcIbCL4KHzY3a6xM9606 rogid:nXO2Z6Qn8EQGfziT8dnWz1pbK/w9606 rigid:/AFat0DrynAJ5ofEnoPSTThlxCE false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9BY14 uniprotkb:P05455 intact:EBI-12549378|ensembl:ENSP00000472769|uniprotkb:Q7L5R2|uniprotkb:Q9BPY7 intact:EBI-358037|ensembl:ENSP00000260956|ensembl:ENSP00000386636|uniprotkb:Q15367|uniprotkb:Q53XJ4 psi-mi:tx101_human(display_long)|uniprotkb:TEX101(gene name)|psi-mi:TEX101(display_short)|uniprotkb:Cell surface receptor NYD-SP8(gene name synonym)|uniprotkb:SGRG(gene name synonym)|uniprotkb:Scleroderma-associated autoantigen(gene name synonym)|uniprotkb:Spermatogenesis-related gene protein(gene name synonym)|uniprotkb:UNQ867/PRO1884(orf name) psi-mi:la_human(display_long)|uniprotkb:SSB(gene name)|psi-mi:SSB(display_short)|uniprotkb:Sjoegren syndrome type B antigen(gene name synonym)|uniprotkb:La ribonucleoprotein(gene name synonym)|uniprotkb:La autoantigen(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Schiza et al. (2018) imex:IM-28077|pubmed:30097533 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-25505061|imex:IM-28077-3 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000131126(gene)|ensembl:ENST00000598265(transcript)|go:"GO:0001669"(acrosomal vesicle)|go:"GO:0002080"(acrosomal membrane)|go:"GO:0005576"(extracellular region)|go:"GO:0005886"(plasma membrane)|go:"GO:0007339"(binding of sperm to zona pellucida)|go:"GO:0009566"(fertilization)|go:"GO:0030317"(flagellated sperm motility)|go:"GO:0044853"(plasma membrane raft)|go:"GO:0046658"(anchored component of plasma membrane)|go:"GO:1901317"(regulation of flagellated sperm motility)|interpro:IPR016054(Ly-6 antigen / uPA receptor -like)|rcsb pdb:7BPR|reactome:R-HSA-163125|refseq:NP_001123483.1|refseq:NP_113639.4 refseq:NP_003133.1|ensembl:ENSG00000138385(gene)|ensembl:ENST00000260956(transcript)|ensembl:ENST00000409333(transcript)|go:"GO:0000049"(tRNA binding)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0001682"(tRNA 5'-leader removal)|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006400"(tRNA modification)|go:"GO:0006409"(tRNA export from nucleus)|go:"GO:0008033"(tRNA processing)|go:"GO:0008266"("poly(U) RNA binding")|go:"GO:0008334"(histone mRNA metabolic process)|go:"GO:0042780"(tRNA 3'-end processing)|go:"GO:0071045"(nuclear histone mRNA catabolic process)|refseq:NP_001281074.1|dip:DIP-29750N|go:"GO:0075522"(IRES-dependent viral translational initiation)|go:"GO:1903608"(protein localization to cytoplasmic stress granule)|go:"GO:1990825"(sequence-specific mRNA binding)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR002344(Lupus La protein)|interpro:IPR006630(RNA-binding protein Lupus La)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR014886(RNA binding motif)|interpro:IPR035979|interpro:IPR036388|interpro:IPR036390|mint:P05455|rcsb pdb:1OWX|rcsb pdb:1S79|rcsb pdb:1S7A|rcsb pdb:1YTY|rcsb pdb:1ZH5|rcsb pdb:2VOD|rcsb pdb:2VON|rcsb pdb:2VOO|rcsb pdb:2VOP|reactome:R-HSA-73980|reactome:R-HSA-749476 - - - figure legend:Fig.2A,Supp Table S5|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-testis)|taxid:9606(Homo sapiens) - 2020/03/24 2021/11/30 rogid:ZE4tXTFi7lUCcIbCL4KHzY3a6xM9606 rogid:Lgpr3jgLWGk3AZzPwjB1swJRsoQ9606 rigid:/AFat0DrynAJ5ofEnoPSTThlxCE false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9BY14 uniprotkb:P18669 intact:EBI-12549378|ensembl:ENSP00000472769|uniprotkb:Q7L5R2|uniprotkb:Q9BPY7 intact:EBI-717905|uniprotkb:Q9BWC0|ensembl:ENSP00000359991 psi-mi:tx101_human(display_long)|uniprotkb:TEX101(gene name)|psi-mi:TEX101(display_short)|uniprotkb:Cell surface receptor NYD-SP8(gene name synonym)|uniprotkb:SGRG(gene name synonym)|uniprotkb:Scleroderma-associated autoantigen(gene name synonym)|uniprotkb:Spermatogenesis-related gene protein(gene name synonym)|uniprotkb:UNQ867/PRO1884(orf name) psi-mi:pgam1_human(display_long)|uniprotkb:Phosphoglycerate mutase isozyme B(gene name synonym)|uniprotkb:BPG-dependent PGAM 1(gene name synonym)|uniprotkb:PGAM1(gene name)|psi-mi:PGAM1(display_short)|uniprotkb:CDABP0006(orf name)|uniprotkb:PGAMA(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Schiza et al. (2018) imex:IM-28077|pubmed:30097533 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-25505061|imex:IM-28077-3 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000131126(gene)|ensembl:ENST00000598265(transcript)|go:"GO:0001669"(acrosomal vesicle)|go:"GO:0002080"(acrosomal membrane)|go:"GO:0005576"(extracellular region)|go:"GO:0005886"(plasma membrane)|go:"GO:0007339"(binding of sperm to zona pellucida)|go:"GO:0009566"(fertilization)|go:"GO:0030317"(flagellated sperm motility)|go:"GO:0044853"(plasma membrane raft)|go:"GO:0046658"(anchored component of plasma membrane)|go:"GO:1901317"(regulation of flagellated sperm motility)|interpro:IPR016054(Ly-6 antigen / uPA receptor -like)|rcsb pdb:7BPR|reactome:R-HSA-163125|refseq:NP_001123483.1|refseq:NP_113639.4 refseq:NP_002620.1|ensembl:ENSG00000171314(gene)|ensembl:ENST00000334828(transcript)|go:"GO:0004082"(bisphosphoglycerate mutase activity)|go:"GO:0004619"(phosphoglycerate mutase activity)|go:"GO:0005576"(extracellular region)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006096"(glycolytic process)|go:"GO:0006110"(regulation of glycolytic process)|go:"GO:0016020"(membrane)|go:"GO:0016787"(hydrolase activity)|go:"GO:0019901"(protein kinase binding)|go:"GO:0034774"(secretory granule lumen)|go:"GO:0043456"(regulation of pentose-phosphate shunt)|go:"GO:0045730"(respiratory burst)|go:"GO:0070062"(extracellular exosome)|go:"GO:1904813"(ficolin-1-rich granule lumen)|interpro:IPR001345(Phosphoglycerate/bisphosphoglycerate mutase)|interpro:IPR005952(Phosphoglycerate mutase 1)|interpro:IPR013078(Phosphoglycerate mutase)|interpro:IPR029033|mint:P18669|rcsb pdb:1LJD|rcsb pdb:1YFK|rcsb pdb:1YJX|rcsb pdb:4GPI|rcsb pdb:4GPZ|rcsb pdb:5Y2I|rcsb pdb:5Y2U|rcsb pdb:5Y35|rcsb pdb:5Y64|rcsb pdb:5Y65|rcsb pdb:5ZRM|rcsb pdb:5ZS8|rcsb pdb:6ISN|reactome:R-HSA-6798695|reactome:R-HSA-70171|reactome:R-HSA-70263 - - - figure legend:Fig.2A,Supp Table S5|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-testis)|taxid:9606(Homo sapiens) - 2020/03/24 2021/11/30 rogid:ZE4tXTFi7lUCcIbCL4KHzY3a6xM9606 rogid:GI6jwRrX08owCyzx8KnRU8QP2rg9606 rigid:/AFat0DrynAJ5ofEnoPSTThlxCE false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9BY14 uniprotkb:P13798 intact:EBI-12549378|ensembl:ENSP00000472769|uniprotkb:Q7L5R2|uniprotkb:Q9BPY7 intact:EBI-723792|ensembl:ENSP00000296456|uniprotkb:Q9BQ33|uniprotkb:Q9P0Y2 psi-mi:tx101_human(display_long)|uniprotkb:TEX101(gene name)|psi-mi:TEX101(display_short)|uniprotkb:Cell surface receptor NYD-SP8(gene name synonym)|uniprotkb:SGRG(gene name synonym)|uniprotkb:Scleroderma-associated autoantigen(gene name synonym)|uniprotkb:Spermatogenesis-related gene protein(gene name synonym)|uniprotkb:UNQ867/PRO1884(orf name) psi-mi:acph_human(display_long)|uniprotkb:Acyl-peptide hydrolase(gene name synonym)|uniprotkb:Acylaminoacyl-peptidase(gene name synonym)|uniprotkb:Oxidized protein hydrolase(gene name synonym)|uniprotkb:APEH(gene name)|psi-mi:APEH(display_short)|uniprotkb:D3F15S2(gene name synonym)|uniprotkb:D3S48E(gene name synonym)|uniprotkb:DNF15S2(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Schiza et al. (2018) imex:IM-28077|pubmed:30097533 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-25505061|imex:IM-28077-3 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000131126(gene)|ensembl:ENST00000598265(transcript)|go:"GO:0001669"(acrosomal vesicle)|go:"GO:0002080"(acrosomal membrane)|go:"GO:0005576"(extracellular region)|go:"GO:0005886"(plasma membrane)|go:"GO:0007339"(binding of sperm to zona pellucida)|go:"GO:0009566"(fertilization)|go:"GO:0030317"(flagellated sperm motility)|go:"GO:0044853"(plasma membrane raft)|go:"GO:0046658"(anchored component of plasma membrane)|go:"GO:1901317"(regulation of flagellated sperm motility)|interpro:IPR016054(Ly-6 antigen / uPA receptor -like)|rcsb pdb:7BPR|reactome:R-HSA-163125|refseq:NP_001123483.1|refseq:NP_113639.4 refseq:XP_011531962.1|refseq:NP_001631.3|ensembl:ENSG00000164062(gene)|ensembl:ENST00000296456(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0004252"(serine-type endopeptidase activity)|go:"GO:0005576"(extracellular region)|go:"GO:0005829"(cytosol)|go:"GO:0006415"(translational termination)|go:"GO:0006508"(proteolysis)|go:"GO:0008242"(omega peptidase activity)|go:"GO:0031965"(nuclear membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0050435"(amyloid-beta metabolic process)|go:"GO:0070062"(extracellular exosome)|go:"GO:1904813"(ficolin-1-rich granule lumen)|interpro:IPR001375(Peptidase S9, prolyl oligopeptidase active site region)|interpro:IPR002471(Peptidase S9, serine active site)|interpro:IPR011042(Six-bladed beta-propeller, TolB-like)|interpro:IPR029058|reactome:R-HSA-6798695|reactome:R-HSA-72764 - - - figure legend:Fig.2A,Supp Table S5|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-testis)|taxid:9606(Homo sapiens) - 2020/03/24 2021/11/30 rogid:ZE4tXTFi7lUCcIbCL4KHzY3a6xM9606 rogid:vkyLSLi3WpS01GRu7YwDpq+yMsI9606 rigid:/AFat0DrynAJ5ofEnoPSTThlxCE false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9BY14 uniprotkb:P05026 intact:EBI-12549378|ensembl:ENSP00000472769|uniprotkb:Q7L5R2|uniprotkb:Q9BPY7 intact:EBI-714630|ensembl:ENSP00000356789|ensembl:ENSP00000356790|uniprotkb:Q5TGZ3 psi-mi:tx101_human(display_long)|uniprotkb:TEX101(gene name)|psi-mi:TEX101(display_short)|uniprotkb:Cell surface receptor NYD-SP8(gene name synonym)|uniprotkb:SGRG(gene name synonym)|uniprotkb:Scleroderma-associated autoantigen(gene name synonym)|uniprotkb:Spermatogenesis-related gene protein(gene name synonym)|uniprotkb:UNQ867/PRO1884(orf name) psi-mi:at1b1_human(display_long)|uniprotkb:Sodium/potassium-dependent ATPase subunit beta-1(gene name synonym)|uniprotkb:ATP1B1(gene name)|psi-mi:ATP1B1(display_short)|uniprotkb:ATP1B(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Schiza et al. (2018) imex:IM-28077|pubmed:30097533 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-25505061|imex:IM-28077-3 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000131126(gene)|ensembl:ENST00000598265(transcript)|go:"GO:0001669"(acrosomal vesicle)|go:"GO:0002080"(acrosomal membrane)|go:"GO:0005576"(extracellular region)|go:"GO:0005886"(plasma membrane)|go:"GO:0007339"(binding of sperm to zona pellucida)|go:"GO:0009566"(fertilization)|go:"GO:0030317"(flagellated sperm motility)|go:"GO:0044853"(plasma membrane raft)|go:"GO:0046658"(anchored component of plasma membrane)|go:"GO:1901317"(regulation of flagellated sperm motility)|interpro:IPR016054(Ly-6 antigen / uPA receptor -like)|rcsb pdb:7BPR|reactome:R-HSA-163125|refseq:NP_001123483.1|refseq:NP_113639.4 ensembl:ENSG00000143153(gene)|ensembl:ENST00000367815(transcript)|ensembl:ENST00000367816(transcript)|go:"GO:0001666"(response to hypoxia)|go:"GO:0001671"(ATPase activator activity)|go:"GO:0005391"("P-type sodium:potassium-exchanging transporter activity")|go:"GO:0005886"(plasma membrane)|go:"GO:0005890"("sodium:potassium-exchanging ATPase complex")|go:"GO:0005901"(caveola)|go:"GO:0006874"(cellular calcium ion homeostasis)|go:"GO:0006883"(cellular sodium ion homeostasis)|go:"GO:0007155"(cell adhesion)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0010248"(establishment or maintenance of transmembrane electrochemical gradient)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0010882"(regulation of cardiac muscle contraction by calcium ion signaling)|go:"GO:0014704"(intercalated disc)|go:"GO:0016020"(membrane)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0016328"(lateral plasma membrane)|go:"GO:0019901"(protein kinase binding)|go:"GO:0023026"(MHC class II protein complex binding)|go:"GO:0030007"(cellular potassium ion homeostasis)|go:"GO:0030315"(T-tubule)|go:"GO:0030674"(protein-macromolecule adaptor activity)|go:"GO:0031090"(organelle membrane)|go:"GO:0032781"(positive regulation of ATP-dependent activity)|go:"GO:0035725"(sodium ion transmembrane transport)|interpro:IPR015565(Sodium/Potassium-Dependent ATPase Beta-1 Subunit)|interpro:IPR038702|mint:P05026|reactome:R-HSA-210991|reactome:R-HSA-5578775|reactome:R-HSA-936837|reactome:R-HSA-9679191|go:"GO:0050821"(protein stabilization)|go:"GO:0051117"(ATPase binding)|go:"GO:0055119"(relaxation of cardiac muscle)|go:"GO:0060048"(cardiac muscle contraction)|go:"GO:0070062"(extracellular exosome)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0086009"(membrane repolarization)|go:"GO:0086013"(membrane repolarization during cardiac muscle cell action potential)|go:"GO:0086064"(cell communication by electrical coupling involved in cardiac conduction)|go:"GO:0098655"(cation transmembrane transport)|go:"GO:1901018"(positive regulation of potassium ion transmembrane transporter activity)|go:"GO:1903278"(positive regulation of sodium ion export across plasma membrane)|go:"GO:1903281"("positive regulation of calcium:sodium antiporter activity")|go:"GO:1903288"(positive regulation of potassium ion import across plasma membrane)|go:"GO:1903408"("positive regulation of P-type sodium:potassium-exchanging transporter activity")|go:"GO:1903561"(extracellular vesicle)|go:"GO:1990573"(potassium ion import across plasma membrane)|interpro:IPR000402(ATPase, P-type cation exchange, beta subunit)|go:"GO:0036126"(sperm flagellum)|go:"GO:0036376"(sodium ion export across plasma membrane)|go:"GO:0042383"(sarcolemma)|go:"GO:0044861"(protein transport into plasma membrane raft)|go:"GO:0046034"(ATP metabolic process)|go:"GO:0046982"(protein heterodimerization activity)|refseq:NP_001668.1 - - - figure legend:Fig.2A,Supp Table S5|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-testis)|taxid:9606(Homo sapiens) - 2020/03/24 2021/11/30 rogid:ZE4tXTFi7lUCcIbCL4KHzY3a6xM9606 rogid:kE/mTDRgwTdf/AWUD0ZFpPN4FkE9606 rigid:/AFat0DrynAJ5ofEnoPSTThlxCE false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9BY14 uniprotkb:P10606 intact:EBI-12549378|ensembl:ENSP00000472769|uniprotkb:Q7L5R2|uniprotkb:Q9BPY7 intact:EBI-1053725|uniprotkb:Q96J18|uniprotkb:Q99610|uniprotkb:Q53YB7|ensembl:ENSP00000258424 psi-mi:tx101_human(display_long)|uniprotkb:TEX101(gene name)|psi-mi:TEX101(display_short)|uniprotkb:Cell surface receptor NYD-SP8(gene name synonym)|uniprotkb:SGRG(gene name synonym)|uniprotkb:Scleroderma-associated autoantigen(gene name synonym)|uniprotkb:Spermatogenesis-related gene protein(gene name synonym)|uniprotkb:UNQ867/PRO1884(orf name) psi-mi:cox5b_human(display_long)|uniprotkb:Cytochrome c oxidase polypeptide Vb(gene name synonym)|uniprotkb:COX5B(gene name)|psi-mi:COX5B(display_short) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Schiza et al. (2018) imex:IM-28077|pubmed:30097533 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-25505061|imex:IM-28077-3 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000131126(gene)|ensembl:ENST00000598265(transcript)|go:"GO:0001669"(acrosomal vesicle)|go:"GO:0002080"(acrosomal membrane)|go:"GO:0005576"(extracellular region)|go:"GO:0005886"(plasma membrane)|go:"GO:0007339"(binding of sperm to zona pellucida)|go:"GO:0009566"(fertilization)|go:"GO:0030317"(flagellated sperm motility)|go:"GO:0044853"(plasma membrane raft)|go:"GO:0046658"(anchored component of plasma membrane)|go:"GO:1901317"(regulation of flagellated sperm motility)|interpro:IPR016054(Ly-6 antigen / uPA receptor -like)|rcsb pdb:7BPR|reactome:R-HSA-163125|refseq:NP_001123483.1|refseq:NP_113639.4 refseq:NP_001853.2|ensembl:ENSG00000135940(gene)|ensembl:ENST00000258424(transcript)|go:"GO:0004129"(cytochrome-c oxidase activity)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005751"(mitochondrial respiratory chain complex IV)|go:"GO:0006123"(mitochondrial electron transport, cytochrome c to oxygen)|go:"GO:0007585"(respiratory gaseous exchange by respiratory system)|go:"GO:0046872"(metal ion binding)|interpro:IPR002124(Cytochrome c oxidase, subunit Vb)|interpro:IPR020893|interpro:IPR036972|rcsb pdb:5Z62|reactome:R-HSA-5628897|reactome:R-HSA-611105|reactome:R-HSA-9707564 - - - figure legend:Fig.2A,Supp Table S5|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-testis)|taxid:9606(Homo sapiens) - 2020/03/24 2021/11/30 rogid:ZE4tXTFi7lUCcIbCL4KHzY3a6xM9606 rogid:EG8kMS2jKMWzQQokTXS2bYk4fHc9606 rigid:/AFat0DrynAJ5ofEnoPSTThlxCE false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9BY14 uniprotkb:P07099 intact:EBI-12549378|ensembl:ENSP00000472769|uniprotkb:Q7L5R2|uniprotkb:Q9BPY7 intact:EBI-6138796|uniprotkb:B2R8N0|uniprotkb:Q5VTJ6|uniprotkb:Q9NP75|uniprotkb:Q9NPE7|uniprotkb:Q9NQU6|uniprotkb:Q9NQU7|uniprotkb:Q9NQU8|uniprotkb:Q9NQU9|uniprotkb:Q9NQV0|uniprotkb:Q9NQV1|uniprotkb:Q9NQV2|ensembl:ENSP00000272167|ensembl:ENSP00000355802|ensembl:ENSP00000480004 psi-mi:tx101_human(display_long)|uniprotkb:TEX101(gene name)|psi-mi:TEX101(display_short)|uniprotkb:Cell surface receptor NYD-SP8(gene name synonym)|uniprotkb:SGRG(gene name synonym)|uniprotkb:Scleroderma-associated autoantigen(gene name synonym)|uniprotkb:Spermatogenesis-related gene protein(gene name synonym)|uniprotkb:UNQ867/PRO1884(orf name) psi-mi:hyep_human(display_long)|uniprotkb:EPHX1(gene name)|psi-mi:EPHX1(display_short)|uniprotkb:EPHX(gene name synonym)|uniprotkb:EPOX(gene name synonym)|uniprotkb:Epoxide hydratase(gene name synonym)|uniprotkb:Microsomal epoxide hydrolase(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Schiza et al. (2018) imex:IM-28077|pubmed:30097533 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-25505061|imex:IM-28077-3 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000131126(gene)|ensembl:ENST00000598265(transcript)|go:"GO:0001669"(acrosomal vesicle)|go:"GO:0002080"(acrosomal membrane)|go:"GO:0005576"(extracellular region)|go:"GO:0005886"(plasma membrane)|go:"GO:0007339"(binding of sperm to zona pellucida)|go:"GO:0009566"(fertilization)|go:"GO:0030317"(flagellated sperm motility)|go:"GO:0044853"(plasma membrane raft)|go:"GO:0046658"(anchored component of plasma membrane)|go:"GO:1901317"(regulation of flagellated sperm motility)|interpro:IPR016054(Ly-6 antigen / uPA receptor -like)|rcsb pdb:7BPR|reactome:R-HSA-163125|refseq:NP_001123483.1|refseq:NP_113639.4 refseq:NP_001278092.1|refseq:NP_000111.1|refseq:NP_001129490.1|ensembl:ENSG00000143819(gene)|ensembl:ENST00000272167(transcript)|ensembl:ENST00000366837(transcript)|ensembl:ENST00000614058(transcript)|go:"GO:0004301"(epoxide hydrolase activity)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006805"(xenobiotic metabolic process)|go:"GO:0009636"(response to toxic substance)|go:"GO:0014070"(response to organic cyclic compound)|go:"GO:0016021"(integral component of membrane)|go:"GO:0019369"(arachidonic acid metabolic process)|go:"GO:0019439"(aromatic compound catabolic process)|go:"GO:0033961"(cis-stilbene-oxide hydrolase activity)|go:"GO:0097176"(epoxide metabolic process)|interpro:IPR000073(Alpha/beta hydrolase fold-1)|interpro:IPR000639(Epoxide hydrolase-like)|interpro:IPR016292(Epoxide hydrolase)|interpro:IPR029058|reactome:R-HSA-211945 - - - figure legend:Fig.2A,Supp Table S5|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-testis)|taxid:9606(Homo sapiens) - 2020/03/24 2021/11/30 rogid:ZE4tXTFi7lUCcIbCL4KHzY3a6xM9606 rogid:VtIgDuQpQQbLSdFLOBBx9yHHiBE9606 rigid:/AFat0DrynAJ5ofEnoPSTThlxCE false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9BY14 uniprotkb:P46777 intact:EBI-12549378|ensembl:ENSP00000472769|uniprotkb:Q7L5R2|uniprotkb:Q9BPY7 intact:EBI-358018|ensembl:ENSP00000359345|uniprotkb:Q53HH6|uniprotkb:Q9H3F4|uniprotkb:Q32LZ3 psi-mi:tx101_human(display_long)|uniprotkb:TEX101(gene name)|psi-mi:TEX101(display_short)|uniprotkb:Cell surface receptor NYD-SP8(gene name synonym)|uniprotkb:SGRG(gene name synonym)|uniprotkb:Scleroderma-associated autoantigen(gene name synonym)|uniprotkb:Spermatogenesis-related gene protein(gene name synonym)|uniprotkb:UNQ867/PRO1884(orf name) psi-mi:rl5_human(display_long)|uniprotkb:RPL5(gene name)|psi-mi:RPL5(display_short)|uniprotkb:Large ribosomal subunit protein uL18(gene name synonym)|uniprotkb:MSTP030(orf name) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Schiza et al. (2018) imex:IM-28077|pubmed:30097533 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-25505061|imex:IM-28077-3 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000131126(gene)|ensembl:ENST00000598265(transcript)|go:"GO:0001669"(acrosomal vesicle)|go:"GO:0002080"(acrosomal membrane)|go:"GO:0005576"(extracellular region)|go:"GO:0005886"(plasma membrane)|go:"GO:0007339"(binding of sperm to zona pellucida)|go:"GO:0009566"(fertilization)|go:"GO:0030317"(flagellated sperm motility)|go:"GO:0044853"(plasma membrane raft)|go:"GO:0046658"(anchored component of plasma membrane)|go:"GO:1901317"(regulation of flagellated sperm motility)|interpro:IPR016054(Ly-6 antigen / uPA receptor -like)|rcsb pdb:7BPR|reactome:R-HSA-163125|refseq:NP_001123483.1|refseq:NP_113639.4 go:"GO:0016020"(membrane)|go:"GO:0022625"(cytosolic large ribosomal subunit)|go:"GO:0022626"(cytosolic ribosome)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0042273"(ribosomal large subunit biogenesis)|go:"GO:0045202"(synapse)|ensembl:ENSG00000122406(gene)|go:"GO:0045727"(positive regulation of translation)|go:"GO:0048027"(mRNA 5'-UTR binding)|go:"GO:0050821"(protein stabilization)|go:"GO:0070062"(extracellular exosome)|go:"GO:1901796"(regulation of signal transduction by p53 class mediator)|ensembl:ENST00000370321(transcript)|go:"GO:0000027"(ribosomal large subunit assembly)|go:"GO:0002181"(cytoplasmic translation)|go:"GO:0003723"(RNA binding)|go:"GO:0003730"(mRNA 3'-UTR binding)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005829"(cytosol)|go:"GO:0005925"(focal adhesion)|go:"GO:0006364"(rRNA processing)|go:"GO:0006412"(translation)|go:"GO:0008097"(5S rRNA binding)|go:"GO:0010628"(positive regulation of gene expression)|refseq:NP_000960.2|dip:DIP-31152N|go:"GO:1904667"(negative regulation of ubiquitin protein ligase activity)|go:"GO:1990904"(ribonucleoprotein complex)|go:"GO:1990948"(ubiquitin ligase inhibitor activity)|go:"GO:2000059"(negative regulation of ubiquitin-dependent protein catabolic process)|go:"GO:2000435"(negative regulation of protein neddylation)|interpro:IPR005485(Ribosomal protein L5, eukaryotic)|interpro:IPR025607|mint:P46777|rcsb pdb:4UG0|rcsb pdb:4V6X|rcsb pdb:5AJ0|rcsb pdb:5LKS|rcsb pdb:5T2C|rcsb pdb:6EK0|rcsb pdb:6IP5|rcsb pdb:6IP6|rcsb pdb:6IP8|rcsb pdb:6LQM|rcsb pdb:6LSR|rcsb pdb:6LSS|rcsb pdb:6LU8|rcsb pdb:6OLE|rcsb pdb:6OLF|rcsb pdb:6OLG|rcsb pdb:6OLI|rcsb pdb:6OLZ|rcsb pdb:6OM0|rcsb pdb:6OM7|rcsb pdb:6QZP|rcsb pdb:6W6L|rcsb pdb:6XA1|rcsb pdb:6Y0G|rcsb pdb:6Y2L|rcsb pdb:6Y57|rcsb pdb:6Y6X|rcsb pdb:6Z6L|rcsb pdb:6Z6M|rcsb pdb:6Z6N|rcsb pdb:6ZM7|rcsb pdb:6ZME|rcsb pdb:6ZMI|rcsb pdb:6ZMO|rcsb pdb:7BHP|reactome:R-HSA-156827|reactome:R-HSA-156902|reactome:R-HSA-1799339|reactome:R-HSA-192823|reactome:R-HSA-2408557|reactome:R-HSA-6791226|reactome:R-HSA-72689|reactome:R-HSA-72706|reactome:R-HSA-72764|reactome:R-HSA-9010553|reactome:R-HSA-9633012|reactome:R-HSA-975956|reactome:R-HSA-975957 - - - figure legend:Fig.2A,Supp Table S5|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-testis)|taxid:9606(Homo sapiens) - 2020/03/24 2021/11/30 rogid:ZE4tXTFi7lUCcIbCL4KHzY3a6xM9606 rogid:rs+zAc+IPrEqv7DHNcy2GIkQkfY9606 rigid:/AFat0DrynAJ5ofEnoPSTThlxCE false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9BY14 uniprotkb:O15260 intact:EBI-12549378|ensembl:ENSP00000472769|uniprotkb:Q7L5R2|uniprotkb:Q9BPY7 intact:EBI-1044848|uniprotkb:O60923|uniprotkb:Q9UNZ0|uniprotkb:Q9UNZ1|uniprotkb:Q5T8U6|ensembl:ENSP00000361057|ensembl:ENSP00000486049|uniprotkb:B7Z6A4 psi-mi:tx101_human(display_long)|uniprotkb:TEX101(gene name)|psi-mi:TEX101(display_short)|uniprotkb:Cell surface receptor NYD-SP8(gene name synonym)|uniprotkb:SGRG(gene name synonym)|uniprotkb:Scleroderma-associated autoantigen(gene name synonym)|uniprotkb:Spermatogenesis-related gene protein(gene name synonym)|uniprotkb:UNQ867/PRO1884(orf name) psi-mi:surf4_human(display_long)|uniprotkb:SURF4(gene name)|psi-mi:SURF4(display_short)|uniprotkb:SURF-4(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Schiza et al. (2018) imex:IM-28077|pubmed:30097533 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-25505061|imex:IM-28077-3 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000131126(gene)|ensembl:ENST00000598265(transcript)|go:"GO:0001669"(acrosomal vesicle)|go:"GO:0002080"(acrosomal membrane)|go:"GO:0005576"(extracellular region)|go:"GO:0005886"(plasma membrane)|go:"GO:0007339"(binding of sperm to zona pellucida)|go:"GO:0009566"(fertilization)|go:"GO:0030317"(flagellated sperm motility)|go:"GO:0044853"(plasma membrane raft)|go:"GO:0046658"(anchored component of plasma membrane)|go:"GO:1901317"(regulation of flagellated sperm motility)|interpro:IPR016054(Ly-6 antigen / uPA receptor -like)|rcsb pdb:7BPR|reactome:R-HSA-163125|refseq:NP_001123483.1|refseq:NP_113639.4 refseq:NP_149351.1|ensembl:ENSG00000148248(gene)|ensembl:ENSG00000280951(gene)|ensembl:ENST00000629578(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005793"(endoplasmic reticulum-Golgi intermediate compartment)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0007030"(Golgi organization)|go:"GO:0010638"(positive regulation of organelle organization)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030133"(transport vesicle)|go:"GO:0033116"(endoplasmic reticulum-Golgi intermediate compartment membrane)|go:"GO:0035577"(azurophil granule membrane)|interpro:IPR002995(Surfeit locus 4)|mint:O15260|reactome:R-HSA-6798695|reactome:R-HSA-6811434|ensembl:ENST00000371989(transcript)|refseq:NP_001267718.1|refseq:NP_001267721.1 - - - figure legend:Fig.2A,Supp Table S5|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-testis)|taxid:9606(Homo sapiens) - 2020/03/24 2021/11/30 rogid:ZE4tXTFi7lUCcIbCL4KHzY3a6xM9606 rogid:VEkKSEfWLmSZx209HLRfoMMTzsg9606 rigid:/AFat0DrynAJ5ofEnoPSTThlxCE false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9BY14 uniprotkb:Q9HB40 intact:EBI-12549378|ensembl:ENSP00000472769|uniprotkb:Q7L5R2|uniprotkb:Q9BPY7 intact:EBI-13943440|uniprotkb:Q96A94|uniprotkb:Q9H3F0|ensembl:ENSP00000262288 psi-mi:tx101_human(display_long)|uniprotkb:TEX101(gene name)|psi-mi:TEX101(display_short)|uniprotkb:Cell surface receptor NYD-SP8(gene name synonym)|uniprotkb:SGRG(gene name synonym)|uniprotkb:Scleroderma-associated autoantigen(gene name synonym)|uniprotkb:Spermatogenesis-related gene protein(gene name synonym)|uniprotkb:UNQ867/PRO1884(orf name) psi-mi:risc_human(display_long)|uniprotkb:SCPEP1(gene name)|psi-mi:SCPEP1(display_short)|uniprotkb:RISC(gene name synonym)|uniprotkb:SCP1(gene name synonym)|uniprotkb:Serine carboxypeptidase 1(gene name synonym)|uniprotkb:MSTP034(orf name)|uniprotkb:UNQ265/PRO302(orf name) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Schiza et al. (2018) imex:IM-28077|pubmed:30097533 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-25505061|imex:IM-28077-3 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000131126(gene)|ensembl:ENST00000598265(transcript)|go:"GO:0001669"(acrosomal vesicle)|go:"GO:0002080"(acrosomal membrane)|go:"GO:0005576"(extracellular region)|go:"GO:0005886"(plasma membrane)|go:"GO:0007339"(binding of sperm to zona pellucida)|go:"GO:0009566"(fertilization)|go:"GO:0030317"(flagellated sperm motility)|go:"GO:0044853"(plasma membrane raft)|go:"GO:0046658"(anchored component of plasma membrane)|go:"GO:1901317"(regulation of flagellated sperm motility)|interpro:IPR016054(Ly-6 antigen / uPA receptor -like)|rcsb pdb:7BPR|reactome:R-HSA-163125|refseq:NP_001123483.1|refseq:NP_113639.4 refseq:NP_067639.1|ensembl:ENSG00000121064(gene)|ensembl:ENST00000262288(transcript)|go:"GO:0004185"(serine-type carboxypeptidase activity)|go:"GO:0005829"(cytosol)|go:"GO:0042573"(retinoic acid metabolic process)|go:"GO:0045776"(negative regulation of blood pressure)|go:"GO:0070062"(extracellular exosome)|go:"GO:0097746"(blood vessel diameter maintenance)|interpro:IPR001563(Peptidase S10, serine carboxypeptidase)|interpro:IPR018202|interpro:IPR029058 - - - figure legend:Fig.2A,Supp Table S5|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-testis)|taxid:9606(Homo sapiens) - 2020/03/24 2021/11/30 rogid:ZE4tXTFi7lUCcIbCL4KHzY3a6xM9606 rogid:FMuffJ/BPZAqjTvAjmwOPNQjWrY9606 rigid:/AFat0DrynAJ5ofEnoPSTThlxCE false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9BY14 uniprotkb:P53621 intact:EBI-12549378|ensembl:ENSP00000472769|uniprotkb:Q7L5R2|uniprotkb:Q9BPY7 intact:EBI-356273|intact:EBI-1188425|uniprotkb:Q5T201|uniprotkb:Q8IXZ9|intact:EBI-2559704|intact:EBI-11576606|ensembl:ENSP00000241704 psi-mi:tx101_human(display_long)|uniprotkb:TEX101(gene name)|psi-mi:TEX101(display_short)|uniprotkb:Cell surface receptor NYD-SP8(gene name synonym)|uniprotkb:SGRG(gene name synonym)|uniprotkb:Scleroderma-associated autoantigen(gene name synonym)|uniprotkb:Spermatogenesis-related gene protein(gene name synonym)|uniprotkb:UNQ867/PRO1884(orf name) psi-mi:copa_human(display_long)|uniprotkb:COPA(gene name)|psi-mi:COPA(display_short)|uniprotkb:Alpha-coat protein(gene name synonym)|uniprotkb:HEP-COP(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Schiza et al. (2018) imex:IM-28077|pubmed:30097533 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-25505061|imex:IM-28077-3 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000131126(gene)|ensembl:ENST00000598265(transcript)|go:"GO:0001669"(acrosomal vesicle)|go:"GO:0002080"(acrosomal membrane)|go:"GO:0005576"(extracellular region)|go:"GO:0005886"(plasma membrane)|go:"GO:0007339"(binding of sperm to zona pellucida)|go:"GO:0009566"(fertilization)|go:"GO:0030317"(flagellated sperm motility)|go:"GO:0044853"(plasma membrane raft)|go:"GO:0046658"(anchored component of plasma membrane)|go:"GO:1901317"(regulation of flagellated sperm motility)|interpro:IPR016054(Ly-6 antigen / uPA receptor -like)|rcsb pdb:7BPR|reactome:R-HSA-163125|refseq:NP_001123483.1|refseq:NP_113639.4 refseq:NP_001091868.1|refseq:NP_004362.2|ensembl:ENSG00000122218(gene)|ensembl:ENST00000241704(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0005179"(hormone activity)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005615"(extracellular space)|go:"GO:0005737"(cytoplasm)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005829"(cytosol)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0006890"(retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum)|go:"GO:0006891"(intra-Golgi vesicle-mediated transport)|go:"GO:0016020"(membrane)|go:"GO:0030126"(COPI vesicle coat)|go:"GO:0030133"(transport vesicle)|go:"GO:0030157"(pancreatic juice secretion)|go:"GO:0030426"(growth cone)|go:"GO:0070062"(extracellular exosome)|interpro:IPR001680(WD40 repeat)|interpro:IPR006692(Coatomer, WD associated region)|interpro:IPR010714(Coatomer, alpha subunit, C-terminal)|interpro:IPR011048(Cytochrome cd1-nitrite reductase-like, C-terminal haem d1)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR016391(Coatomer, alpha subunit)|interpro:IPR019775|interpro:IPR020472|interpro:IPR024977|interpro:IPR036322|mint:P53621|rcsb pdb:6PBG|rcsb pdb:6TZT|rcsb pdb:6U3V|reactome:R-HSA-6807878|reactome:R-HSA-6811434 - - - figure legend:Fig.2A,Supp Table S5|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-testis)|taxid:9606(Homo sapiens) - 2020/03/24 2021/11/30 rogid:ZE4tXTFi7lUCcIbCL4KHzY3a6xM9606 rogid:9uP/NS7FjPrGDna1wcNHQy9py6A9606 rigid:/AFat0DrynAJ5ofEnoPSTThlxCE false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9BY14 uniprotkb:P48556 intact:EBI-12549378|ensembl:ENSP00000472769|uniprotkb:Q7L5R2|uniprotkb:Q9BPY7 intact:EBI-359304|uniprotkb:Q6P1L7|uniprotkb:B4DX18|ensembl:ENSP00000215071|ensembl:ENSP00000481136 psi-mi:tx101_human(display_long)|uniprotkb:TEX101(gene name)|psi-mi:TEX101(display_short)|uniprotkb:Cell surface receptor NYD-SP8(gene name synonym)|uniprotkb:SGRG(gene name synonym)|uniprotkb:Scleroderma-associated autoantigen(gene name synonym)|uniprotkb:Spermatogenesis-related gene protein(gene name synonym)|uniprotkb:UNQ867/PRO1884(orf name) psi-mi:psmd8_human(display_long)|uniprotkb:PSMD8(gene name)|psi-mi:PSMD8(display_short)|uniprotkb:26S proteasome regulatory subunit S14(gene name synonym)|uniprotkb:p31(gene name synonym)|uniprotkb:26S proteasome regulatory subunit RPN12(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Schiza et al. (2018) imex:IM-28077|pubmed:30097533 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-25505061|imex:IM-28077-3 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000131126(gene)|ensembl:ENST00000598265(transcript)|go:"GO:0001669"(acrosomal vesicle)|go:"GO:0002080"(acrosomal membrane)|go:"GO:0005576"(extracellular region)|go:"GO:0005886"(plasma membrane)|go:"GO:0007339"(binding of sperm to zona pellucida)|go:"GO:0009566"(fertilization)|go:"GO:0030317"(flagellated sperm motility)|go:"GO:0044853"(plasma membrane raft)|go:"GO:0046658"(anchored component of plasma membrane)|go:"GO:1901317"(regulation of flagellated sperm motility)|interpro:IPR016054(Ly-6 antigen / uPA receptor -like)|rcsb pdb:7BPR|reactome:R-HSA-163125|refseq:NP_001123483.1|refseq:NP_113639.4 refseq:NP_002803.2|ensembl:ENSG00000099341(gene)|ensembl:ENST00000215071(transcript)|ensembl:ENST00000620216(transcript)|go:"GO:0000502"(proteasome complex)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005838"(proteasome regulatory particle)|go:"GO:0008541"(proteasome regulatory particle, lid subcomplex)|go:"GO:0022624"(proteasome accessory complex)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|interpro:IPR000717(Proteasome component region PCI)|interpro:IPR006746(26S proteasome non-ATPase regulatory subunit Rpn12)|interpro:IPR033464|mint:P48556|rcsb pdb:5GJQ|rcsb pdb:5GJR|rcsb pdb:5L4K|rcsb pdb:5LN3|rcsb pdb:5T0C|rcsb pdb:5T0G|rcsb pdb:5M32|rcsb pdb:5T0H|rcsb pdb:5T0I|rcsb pdb:5T0J|rcsb pdb:5VFP|rcsb pdb:5VFQ|rcsb pdb:5VFR|rcsb pdb:5VFS|rcsb pdb:5VFT|rcsb pdb:5VFU|rcsb pdb:5VGZ|rcsb pdb:5VHF|rcsb pdb:5VHH|rcsb pdb:5VHI|rcsb pdb:5VHS|rcsb pdb:6MSB|rcsb pdb:6MSD|rcsb pdb:6MSG|rcsb pdb:6MSH|rcsb pdb:6MSJ|rcsb pdb:6MSK|rcsb pdb:6WJD|rcsb pdb:6WJN|reactome:R-HSA-1169091|reactome:R-HSA-1234176|reactome:R-HSA-1236974|reactome:R-HSA-1236978|reactome:R-HSA-174084|reactome:R-HSA-174113|reactome:R-HSA-174154|reactome:R-HSA-174178|reactome:R-HSA-174184|reactome:R-HSA-180585|reactome:R-HSA-187577|reactome:R-HSA-195253|reactome:R-HSA-202424|reactome:R-HSA-211733|reactome:R-HSA-2467813|reactome:R-HSA-2871837|reactome:R-HSA-349425|reactome:R-HSA-350562|reactome:R-HSA-382556|reactome:R-HSA-450408|reactome:R-HSA-4608870|reactome:R-HSA-4641257|reactome:R-HSA-4641258|reactome:R-HSA-5358346|reactome:R-HSA-5362768|reactome:R-HSA-5607761|reactome:R-HSA-5607764|reactome:R-HSA-5610780|reactome:R-HSA-5610783|reactome:R-HSA-5610785|reactome:R-HSA-5632684|reactome:R-HSA-5658442|reactome:R-HSA-5668541|reactome:R-HSA-5676590|reactome:R-HSA-5678895|reactome:R-HSA-5687128|reactome:R-HSA-5689603|reactome:R-HSA-5689880|reactome:R-HSA-68827|reactome:R-HSA-68949|reactome:R-HSA-69017|reactome:R-HSA-69481|reactome:R-HSA-69601|reactome:R-HSA-75815|reactome:R-HSA-8852276|reactome:R-HSA-8854050|reactome:R-HSA-8932339|reactome:R-HSA-8939236|reactome:R-HSA-8939902|reactome:R-HSA-8941858|reactome:R-HSA-8948751|reactome:R-HSA-8951664|reactome:R-HSA-9010553|reactome:R-HSA-9020702|reactome:R-HSA-9604323|reactome:R-HSA-983168|reactome:R-HSA-180534 - - - figure legend:Fig.2A,Supp Table S5|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-testis)|taxid:9606(Homo sapiens) - 2020/03/24 2021/11/30 rogid:ZE4tXTFi7lUCcIbCL4KHzY3a6xM9606 rogid:73qmlkzCwdeHlNzUy7vy7qmIok09606 rigid:/AFat0DrynAJ5ofEnoPSTThlxCE false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9BY14 uniprotkb:P06727 intact:EBI-12549378|ensembl:ENSP00000472769|uniprotkb:Q7L5R2|uniprotkb:Q9BPY7 intact:EBI-1222447|uniprotkb:Q14CW8|uniprotkb:Q6Q787|uniprotkb:A8MSL6|ensembl:ENSP00000350425 psi-mi:tx101_human(display_long)|uniprotkb:TEX101(gene name)|psi-mi:TEX101(display_short)|uniprotkb:Cell surface receptor NYD-SP8(gene name synonym)|uniprotkb:SGRG(gene name synonym)|uniprotkb:Scleroderma-associated autoantigen(gene name synonym)|uniprotkb:Spermatogenesis-related gene protein(gene name synonym)|uniprotkb:UNQ867/PRO1884(orf name) psi-mi:apoa4_human(display_long)|uniprotkb:APOA4(gene name)|psi-mi:APOA4(display_short)|uniprotkb:Apolipoprotein A4(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Schiza et al. (2018) imex:IM-28077|pubmed:30097533 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-25505061|imex:IM-28077-3 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000131126(gene)|ensembl:ENST00000598265(transcript)|go:"GO:0001669"(acrosomal vesicle)|go:"GO:0002080"(acrosomal membrane)|go:"GO:0005576"(extracellular region)|go:"GO:0005886"(plasma membrane)|go:"GO:0007339"(binding of sperm to zona pellucida)|go:"GO:0009566"(fertilization)|go:"GO:0030317"(flagellated sperm motility)|go:"GO:0044853"(plasma membrane raft)|go:"GO:0046658"(anchored component of plasma membrane)|go:"GO:1901317"(regulation of flagellated sperm motility)|interpro:IPR016054(Ly-6 antigen / uPA receptor -like)|rcsb pdb:7BPR|reactome:R-HSA-163125|refseq:NP_001123483.1|refseq:NP_113639.4 refseq:NP_000473.2|dip:DIP-38333N|ensembl:ENSG00000110244(gene)|ensembl:ENST00000357780(transcript)|go:"GO:0002227"(innate immune response in mucosa)|go:"GO:0005319"(lipid transporter activity)|go:"GO:0005507"(copper ion binding)|go:"GO:0005543"(phospholipid binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0005769"(early endosome)|go:"GO:0005788"(endoplasmic reticulum lumen)|go:"GO:0005829"(cytosol)|go:"GO:0006695"(cholesterol biosynthetic process)|go:"GO:0006869"(lipid transport)|go:"GO:0006982"(response to lipid hydroperoxide)|go:"GO:0007159"(leukocyte cell-cell adhesion)|go:"GO:0008203"(cholesterol metabolic process)|go:"GO:0008289"(lipid binding)|go:"GO:0010873"(positive regulation of cholesterol esterification)|go:"GO:0010898"(positive regulation of triglyceride catabolic process)|go:"GO:0015485"(cholesterol binding)|go:"GO:0016042"(lipid catabolic process)|go:"GO:0016209"(antioxidant activity)|go:"GO:0019430"(removal of superoxide radicals)|go:"GO:0030300"(regulation of intestinal cholesterol absorption)|go:"GO:0031210"(phosphatidylcholine binding)|go:"GO:0032374"(regulation of cholesterol transport)|go:"GO:0033344"(cholesterol efflux)|go:"GO:0033700"(phospholipid efflux)|go:"GO:0034361"(very-low-density lipoprotein particle)|go:"GO:0034364"(high-density lipoprotein particle)|go:"GO:0034371"(chylomicron remodeling)|go:"GO:0034372"(very-low-density lipoprotein particle remodeling)|go:"GO:0034375"(high-density lipoprotein particle remodeling)|go:"GO:0034378"(chylomicron assembly)|go:"GO:0034380"(high-density lipoprotein particle assembly)|go:"GO:0034445"(negative regulation of plasma lipoprotein oxidation)|go:"GO:0035634"(response to stilbenoid)|go:"GO:0042157"(lipoprotein metabolic process)|go:"GO:0042627"(chylomicron)|go:"GO:0042632"(cholesterol homeostasis)|go:"GO:0042744"(hydrogen peroxide catabolic process)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043691"(reverse cholesterol transport)|go:"GO:0045723"(positive regulation of fatty acid biosynthetic process)|go:"GO:0046470"(phosphatidylcholine metabolic process)|go:"GO:0046889"(positive regulation of lipid biosynthetic process)|go:"GO:0051006"(positive regulation of lipoprotein lipase activity)|go:"GO:0055088"(lipid homeostasis)|go:"GO:0060228"(phosphatidylcholine-sterol O-acyltransferase activator activity)|go:"GO:0062023"(collagen-containing extracellular matrix)|go:"GO:0065005"(protein-lipid complex assembly)|go:"GO:0070062"(extracellular exosome)|go:"GO:0072562"(blood microparticle)|go:"GO:0120020"(cholesterol transfer activity)|interpro:IPR000074(Apolipoprotein A1/A4/E)|rcsb pdb:3S84|reactome:R-HSA-8963888|reactome:R-HSA-8963889|reactome:R-HSA-8963901|reactome:R-HSA-975634|reactome:R-HSA-977225|go:"GO:0070328"(triglyceride homeostasis) - - - figure legend:Fig.2A,Supp Table S5|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-testis)|taxid:9606(Homo sapiens) - 2020/03/24 2021/11/30 rogid:ZE4tXTFi7lUCcIbCL4KHzY3a6xM9606 rogid:95b7Xlqg/plh9/R7xhLBsMXQscM9606 rigid:/AFat0DrynAJ5ofEnoPSTThlxCE false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9BY14 uniprotkb:P13987 intact:EBI-12549378|ensembl:ENSP00000472769|uniprotkb:Q7L5R2|uniprotkb:Q9BPY7 intact:EBI-297972|ensembl:ENSP00000340210|ensembl:ENSP00000379191|ensembl:ENSP00000403511|ensembl:ENSP00000404822|ensembl:ENSP00000410182|ensembl:ENSP00000432942|ensembl:ENSP00000494884|ensembl:ENSP00000498448|ensembl:ENSP00000498879|uniprotkb:E9PR17 psi-mi:tx101_human(display_long)|uniprotkb:TEX101(gene name)|psi-mi:TEX101(display_short)|uniprotkb:Cell surface receptor NYD-SP8(gene name synonym)|uniprotkb:SGRG(gene name synonym)|uniprotkb:Scleroderma-associated autoantigen(gene name synonym)|uniprotkb:Spermatogenesis-related gene protein(gene name synonym)|uniprotkb:UNQ867/PRO1884(orf name) psi-mi:cd59_human(display_long)|uniprotkb:CD59(gene name)|psi-mi:CD59(display_short)|uniprotkb:Membrane attack complex inhibition factor(gene name synonym)|uniprotkb:MAC-inhibitory protein(gene name synonym)|uniprotkb:Protectin(gene name synonym)|uniprotkb:MEM43 antigen(gene name synonym)|uniprotkb:Membrane inhibitor of reactive lysis(gene name synonym)|uniprotkb:20 kDa homologous restriction factor(gene name synonym)|uniprotkb:1F5 antigen(gene name synonym)|uniprotkb:MIC11(gene name synonym)|uniprotkb:MIN1(gene name synonym)|uniprotkb:MIN2(gene name synonym)|uniprotkb:MIN3(gene name synonym)|uniprotkb:MSK21(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Schiza et al. (2018) imex:IM-28077|pubmed:30097533 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-25505061|imex:IM-28077-3 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000131126(gene)|ensembl:ENST00000598265(transcript)|go:"GO:0001669"(acrosomal vesicle)|go:"GO:0002080"(acrosomal membrane)|go:"GO:0005576"(extracellular region)|go:"GO:0005886"(plasma membrane)|go:"GO:0007339"(binding of sperm to zona pellucida)|go:"GO:0009566"(fertilization)|go:"GO:0030317"(flagellated sperm motility)|go:"GO:0044853"(plasma membrane raft)|go:"GO:0046658"(anchored component of plasma membrane)|go:"GO:1901317"(regulation of flagellated sperm motility)|interpro:IPR016054(Ly-6 antigen / uPA receptor -like)|rcsb pdb:7BPR|reactome:R-HSA-163125|refseq:NP_001123483.1|refseq:NP_113639.4 refseq:NP_000602.1|refseq:NP_001120695.1|refseq:NP_001120697.1|refseq:NP_001120698.1|refseq:NP_001120699.1|refseq:NP_976074.1|refseq:NP_976075.1|refseq:NP_976076.1|ensembl:ENST00000395850(transcript)|ensembl:ENST00000415002(transcript)|ensembl:ENST00000437761(transcript)|ensembl:ENST00000445143(transcript)|ensembl:ENST00000527577(transcript)|ensembl:ENST00000642928(transcript)|ensembl:ENST00000651785(transcript)|ensembl:ENST00000652678(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001848"(complement binding)|go:"GO:0001971"(negative regulation of activation of membrane attack complex)|go:"GO:0005615"(extracellular space)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005886"(plasma membrane)|go:"GO:0005925"(focal adhesion)|go:"GO:0007166"(cell surface receptor signaling pathway)|go:"GO:0007596"(blood coagulation)|go:"GO:0009986"(cell surface)|go:"GO:0012507"(ER to Golgi transport vesicle membrane)|go:"GO:0016020"(membrane)|go:"GO:0030133"(transport vesicle)|go:"GO:0030449"(regulation of complement activation)|go:"GO:0031362"(anchored component of external side of plasma membrane)|go:"GO:0031982"(vesicle)|go:"GO:0033116"(endoplasmic reticulum-Golgi intermediate compartment membrane)|go:"GO:0035579"(specific granule membrane)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070821"(tertiary granule membrane)|go:"GO:1903659"(regulation of complement-dependent cytotoxicity)|interpro:IPR016054(Ly-6 antigen / uPA receptor -like)|interpro:IPR018363|interpro:IPR027101|mint:P13987|rcsb pdb:1CDQ|rcsb pdb:1CDR|rcsb pdb:1CDS|rcsb pdb:1ERG|rcsb pdb:1ERH|rcsb pdb:2J8B|rcsb pdb:2OFS|rcsb pdb:2UWR|rcsb pdb:2UX2|rcsb pdb:4BIK|rcsb pdb:5IMT|rcsb pdb:5IMY|rcsb pdb:6ZD0|reactome:R-HSA-204005|reactome:R-HSA-5694530|reactome:R-HSA-6798695|reactome:R-HSA-6807878|reactome:R-HSA-977606|ensembl:ENSG00000085063(gene)|ensembl:ENST00000351554(transcript) - - - figure legend:Fig.2A,Supp Table S5|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-testis)|taxid:9606(Homo sapiens) - 2020/03/24 2021/11/30 rogid:ZE4tXTFi7lUCcIbCL4KHzY3a6xM9606 rogid:l93Yw04Ax0xODyPzjFqaaMvqBeM9606 rigid:/AFat0DrynAJ5ofEnoPSTThlxCE false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9BY14 uniprotkb:Q09028 intact:EBI-12549378|ensembl:ENSP00000472769|uniprotkb:Q7L5R2|uniprotkb:Q9BPY7 intact:EBI-620823|uniprotkb:B4DRH0|ensembl:ENSP00000362592|uniprotkb:P31149|uniprotkb:Q53H02|uniprotkb:Q96BV9|uniprotkb:D3DPQ3|uniprotkb:B2R6G9 psi-mi:tx101_human(display_long)|uniprotkb:TEX101(gene name)|psi-mi:TEX101(display_short)|uniprotkb:Cell surface receptor NYD-SP8(gene name synonym)|uniprotkb:SGRG(gene name synonym)|uniprotkb:Scleroderma-associated autoantigen(gene name synonym)|uniprotkb:Spermatogenesis-related gene protein(gene name synonym)|uniprotkb:UNQ867/PRO1884(orf name) psi-mi:rbbp4_human(display_long)|uniprotkb:Retinoblastoma-binding protein 4(gene name synonym)|uniprotkb:Retinoblastoma-binding protein p48(gene name synonym)|uniprotkb:Chromatin assembly factor 1 subunit C(gene name synonym)|uniprotkb:Chromatin assembly factor I p48 subunit(gene name synonym)|uniprotkb:Nucleosome-remodeling factor subunit RBAP48(gene name synonym)|uniprotkb:RBBP4(gene name)|psi-mi:RBBP4(display_short)|uniprotkb:RBAP48(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Schiza et al. (2018) imex:IM-28077|pubmed:30097533 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-25505061|imex:IM-28077-3 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000131126(gene)|ensembl:ENST00000598265(transcript)|go:"GO:0001669"(acrosomal vesicle)|go:"GO:0002080"(acrosomal membrane)|go:"GO:0005576"(extracellular region)|go:"GO:0005886"(plasma membrane)|go:"GO:0007339"(binding of sperm to zona pellucida)|go:"GO:0009566"(fertilization)|go:"GO:0030317"(flagellated sperm motility)|go:"GO:0044853"(plasma membrane raft)|go:"GO:0046658"(anchored component of plasma membrane)|go:"GO:1901317"(regulation of flagellated sperm motility)|interpro:IPR016054(Ly-6 antigen / uPA receptor -like)|rcsb pdb:7BPR|reactome:R-HSA-163125|refseq:NP_001123483.1|refseq:NP_113639.4 ensembl:ENSG00000162521(gene)|ensembl:ENST00000373493(transcript)|go:"GO:0000118"(histone deacetylase complex)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006260"(DNA replication)|go:"GO:0006335"(DNA replication-dependent chromatin assembly)|go:"GO:0006336"(DNA replication-independent chromatin assembly)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0007049"(cell cycle)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0016580"(Sin3 complex)|go:"GO:0016581"(NuRD complex)|go:"GO:0016589"(NURF complex)|go:"GO:0031497"(chromatin assembly)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033186"(CAF-1 complex)|go:"GO:0035098"("ESC/E(Z) complex")|go:"GO:0042393"(histone binding)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0043044"|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019775|interpro:IPR020472|interpro:IPR022052|mint:Q09028|rcsb pdb:2XU7|rcsb pdb:3GFC|rcsb pdb:4PBY|rcsb pdb:4PBZ|rcsb pdb:4PC0|rcsb pdb:4R7A|rcsb pdb:5FXY|rcsb pdb:5VTB|rcsb pdb:5WAI|rcsb pdb:5WAK|rcsb pdb:5XWR|rcsb pdb:5XXQ|rcsb pdb:5Y1U|rcsb pdb:6BW3|rcsb pdb:6BW4|rcsb pdb:6C23|rcsb pdb:6C24|rcsb pdb:6G16|rcsb pdb:6NQ3|rcsb pdb:6WKR|rcsb pdb:6ZRC|rcsb pdb:6ZRD|rcsb pdb:7AOA|rcsb pdb:7KSO|rcsb pdb:7KSR|rcsb pdb:7KTP|rcsb pdb:7M40|reactome:R-HSA-1362277|reactome:R-HSA-1362300|reactome:R-HSA-1538133|reactome:R-HSA-156711|reactome:R-HSA-212300|reactome:R-HSA-2559580|reactome:R-HSA-3214815|reactome:R-HSA-3214841|reactome:R-HSA-427389|reactome:R-HSA-5617472|reactome:R-HSA-606279|reactome:R-HSA-6804758|reactome:R-HSA-69202|reactome:R-HSA-69205|reactome:R-HSA-69656|reactome:R-HSA-73762|reactome:R-HSA-8943724|reactome:R-HSA-8953750|reactome:R-HSA-9609690|reactome:R-HSA-9679191|reactome:R-HSA-9710421|interpro:IPR036322|refseq:NP_001128727.1|refseq:NP_001128728.1|refseq:NP_005601.1|dip:DIP-33495N - - - figure legend:Fig.2A,Supp Table S5|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-testis)|taxid:9606(Homo sapiens) - 2020/03/24 2021/11/30 rogid:ZE4tXTFi7lUCcIbCL4KHzY3a6xM9606 rogid:CbyJMIjpW1A4sZijP0IGRYc8o4I9606 rigid:/AFat0DrynAJ5ofEnoPSTThlxCE false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9BY14 uniprotkb:Q59GN2 intact:EBI-12549378|ensembl:ENSP00000472769|uniprotkb:Q7L5R2|uniprotkb:Q9BPY7 intact:EBI-10101575 psi-mi:tx101_human(display_long)|uniprotkb:TEX101(gene name)|psi-mi:TEX101(display_short)|uniprotkb:Cell surface receptor NYD-SP8(gene name synonym)|uniprotkb:SGRG(gene name synonym)|uniprotkb:Scleroderma-associated autoantigen(gene name synonym)|uniprotkb:Spermatogenesis-related gene protein(gene name synonym)|uniprotkb:UNQ867/PRO1884(orf name) psi-mi:r39l5_human(display_long)|uniprotkb:RPL39P5(gene name)|psi-mi:RPL39P5(display_short)|uniprotkb:60S ribosomal protein L39 pseudogene 5(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Schiza et al. (2018) imex:IM-28077|pubmed:30097533 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-25505061|imex:IM-28077-3 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000131126(gene)|ensembl:ENST00000598265(transcript)|go:"GO:0001669"(acrosomal vesicle)|go:"GO:0002080"(acrosomal membrane)|go:"GO:0005576"(extracellular region)|go:"GO:0005886"(plasma membrane)|go:"GO:0007339"(binding of sperm to zona pellucida)|go:"GO:0009566"(fertilization)|go:"GO:0030317"(flagellated sperm motility)|go:"GO:0044853"(plasma membrane raft)|go:"GO:0046658"(anchored component of plasma membrane)|go:"GO:1901317"(regulation of flagellated sperm motility)|interpro:IPR016054(Ly-6 antigen / uPA receptor -like)|rcsb pdb:7BPR|reactome:R-HSA-163125|refseq:NP_001123483.1|refseq:NP_113639.4 interpro:IPR000077(Ribosomal protein L39e)|interpro:IPR023626|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0006412"(translation)|go:"GO:0022625"(cytosolic large ribosomal subunit) - - - figure legend:Fig.2A,Supp Table S5|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-testis)|taxid:9606(Homo sapiens) - 2020/03/24 2021/11/30 rogid:ZE4tXTFi7lUCcIbCL4KHzY3a6xM9606 rogid:vqUrMKZ0TgDiCZbYR2+EBEZS8QY9606 rigid:/AFat0DrynAJ5ofEnoPSTThlxCE false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9BY14 uniprotkb:P11279 intact:EBI-12549378|ensembl:ENSP00000472769|uniprotkb:Q7L5R2|uniprotkb:Q9BPY7 intact:EBI-2805407|uniprotkb:B4DWL3|ensembl:ENSP00000333298|uniprotkb:Q9NP13|uniprotkb:Q8WU33|uniprotkb:Q9BRD2|uniprotkb:Q96I40 psi-mi:tx101_human(display_long)|uniprotkb:TEX101(gene name)|psi-mi:TEX101(display_short)|uniprotkb:Cell surface receptor NYD-SP8(gene name synonym)|uniprotkb:SGRG(gene name synonym)|uniprotkb:Scleroderma-associated autoantigen(gene name synonym)|uniprotkb:Spermatogenesis-related gene protein(gene name synonym)|uniprotkb:UNQ867/PRO1884(orf name) psi-mi:lamp1_human(display_long)|uniprotkb:CD107 antigen-like family member A(gene name synonym)|uniprotkb:LAMP1(gene name)|psi-mi:LAMP1(display_short) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Schiza et al. (2018) imex:IM-28077|pubmed:30097533 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-25505061|imex:IM-28077-3 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000131126(gene)|ensembl:ENST00000598265(transcript)|go:"GO:0001669"(acrosomal vesicle)|go:"GO:0002080"(acrosomal membrane)|go:"GO:0005576"(extracellular region)|go:"GO:0005886"(plasma membrane)|go:"GO:0007339"(binding of sperm to zona pellucida)|go:"GO:0009566"(fertilization)|go:"GO:0030317"(flagellated sperm motility)|go:"GO:0044853"(plasma membrane raft)|go:"GO:0046658"(anchored component of plasma membrane)|go:"GO:1901317"(regulation of flagellated sperm motility)|interpro:IPR016054(Ly-6 antigen / uPA receptor -like)|rcsb pdb:7BPR|reactome:R-HSA-163125|refseq:NP_001123483.1|refseq:NP_113639.4 ensembl:ENSG00000185896(gene)|go:"GO:0016020"(membrane)|go:"GO:0019899"(enzyme binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030285"(integral component of synaptic vesicle membrane)|go:"GO:0030425"(dendrite)|go:"GO:0031902"(late endosome membrane)|go:"GO:0035577"(azurophil granule membrane)|go:"GO:0042383"(sarcolemma)|go:"GO:0042470"(melanosome)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043323"(positive regulation of natural killer cell degranulation)|go:"GO:0044754"(autolysosome)|go:"GO:0045954"(positive regulation of natural killer cell mediated cytotoxicity)|go:"GO:0048102"(autophagic cell death)|go:"GO:0048471"(perinuclear region of cytoplasm)|ensembl:ENST00000332556(transcript)|go:"GO:0000421"(autophagosome membrane)|go:"GO:0001618"(virus receptor activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005764"(lysosome)|go:"GO:0050821"(protein stabilization)|go:"GO:0061474"(phagolysosome membrane)|go:"GO:0070062"(extracellular exosome)|go:"GO:0072594"(establishment of protein localization to organelle)|go:"GO:0090160"(Golgi to lysosome transport)|go:"GO:0097208"(alveolar lamellar body)|go:"GO:0101003"(ficolin-1-rich granule membrane)|go:"GO:0101004"(cytolytic granule membrane)|go:"GO:0140507"(granzyme-mediated programmed cell death signaling pathway)|go:"GO:1902513"(regulation of organelle transport along microtubule)|interpro:IPR002000("Lysosome-associated membrane glycoprotein (Lamp)/CD68")|interpro:IPR018134|mint:P11279|reactome:R-HSA-6798695|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005770"(late endosome)|go:"GO:0005771"(multivesicular body)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0009897"(external side of plasma membrane)|go:"GO:0010008"(endosome membrane)|refseq:NP_005552.3|dip:DIP-44670N - - - figure legend:Fig.2A,Supp Table S5|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-testis)|taxid:9606(Homo sapiens) - 2020/03/24 2021/11/30 rogid:ZE4tXTFi7lUCcIbCL4KHzY3a6xM9606 rogid:dP5MZG0I7/SM0EfCUhsESfQYvYU9606 rigid:/AFat0DrynAJ5ofEnoPSTThlxCE false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9BY14 uniprotkb:Q15746 intact:EBI-12549378|ensembl:ENSP00000472769|uniprotkb:Q7L5R2|uniprotkb:Q9BPY7 intact:EBI-968482|intact:EBI-28987351|ensembl:ENSP00000353452|uniprotkb:O95796|uniprotkb:O95797|uniprotkb:O95798|uniprotkb:O95799|uniprotkb:Q14844|uniprotkb:Q16794|uniprotkb:Q5MY99|uniprotkb:Q5MYA0|intact:EBI-1758586|uniprotkb:B4DUE3|uniprotkb:D3DN97|uniprotkb:Q17S15|uniprotkb:Q6P2N0|uniprotkb:Q7Z4J0|uniprotkb:Q9C0L5|uniprotkb:Q9UBG5|uniprotkb:Q9UIT9|intact:EBI-1963605|uniprotkb:Q3ZCP9|uniprotkb:Q9UBY6 psi-mi:tx101_human(display_long)|uniprotkb:TEX101(gene name)|psi-mi:TEX101(display_short)|uniprotkb:Cell surface receptor NYD-SP8(gene name synonym)|uniprotkb:SGRG(gene name synonym)|uniprotkb:Scleroderma-associated autoantigen(gene name synonym)|uniprotkb:Spermatogenesis-related gene protein(gene name synonym)|uniprotkb:UNQ867/PRO1884(orf name) psi-mi:mylk_human(display_long)|uniprotkb:MYLK(gene name)|psi-mi:MYLK(display_short)|uniprotkb:MLCK(gene name synonym)|uniprotkb:Telokin(gene name synonym)|uniprotkb:Kinase-related protein(gene name synonym)|uniprotkb:MLCK1(gene name synonym)|uniprotkb:MYLK1(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Schiza et al. (2018) imex:IM-28077|pubmed:30097533 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-25505061|imex:IM-28077-3 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000131126(gene)|ensembl:ENST00000598265(transcript)|go:"GO:0001669"(acrosomal vesicle)|go:"GO:0002080"(acrosomal membrane)|go:"GO:0005576"(extracellular region)|go:"GO:0005886"(plasma membrane)|go:"GO:0007339"(binding of sperm to zona pellucida)|go:"GO:0009566"(fertilization)|go:"GO:0030317"(flagellated sperm motility)|go:"GO:0044853"(plasma membrane raft)|go:"GO:0046658"(anchored component of plasma membrane)|go:"GO:1901317"(regulation of flagellated sperm motility)|interpro:IPR016054(Ly-6 antigen / uPA receptor -like)|rcsb pdb:7BPR|reactome:R-HSA-163125|refseq:NP_001123483.1|refseq:NP_113639.4 ensembl:ENSG00000065534(gene)|go:"GO:0006939"(smooth muscle contraction)|go:"GO:0014820"(tonic smooth muscle contraction)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0030027"(lamellipodium)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0032060"(bleb assembly)|go:"GO:0032154"(cleavage furrow)|go:"GO:0046872"(metal ion binding)|go:"GO:0051928"(positive regulation of calcium ion transport)|go:"GO:0060414"(aorta smooth muscle tissue morphogenesis)|go:"GO:0071476"(cellular hypotonic response)|go:"GO:0090303"(positive regulation of wound healing)|interpro:IPR000719(Protein kinase, core)|interpro:IPR003598(Immunoglobulin subtype 2)|interpro:IPR003599(Immunoglobulin subtype)|interpro:IPR003961(Fibronectin, type III)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR013098(Immunoglobulin I-set)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR015725(Myosin Light Chain Kinase)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR036116|ensembl:ENST00000360304(transcript)|go:"GO:0001725"(stress fiber)|go:"GO:0003779"(actin binding)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004687"(myosin light chain kinase activity)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006468"(protein phosphorylation)|interpro:IPR036179|rcsb pdb:2K0F|rcsb pdb:2YR3|rcsb pdb:2CQV|rcsb pdb:5JQA|rcsb pdb:5JTH|rcsb pdb:6C6M|reactome:R-HSA-445355|reactome:R-HSA-5627123|refseq:NP_444253.3|refseq:NP_444254.3|refseq:NP_444255.3|refseq:NP_444256.3|refseq:NP_444259.1|refseq:NP_001308238.1|refseq:XP_011511162.1|ensembl:ENST00000346322|ensembl:ENSP00000320622|ensembl:ENSP00000354004|ensembl:ENST00000418370|ensembl:ENSP00000428967|ensembl:ENST00000578202|ensembl:ENSP00000463691|ensembl:ENST00000583087|ensembl:ENSP00000462118|ensembl:ENST00000360772|ensembl:ENSP00000353452|refseq:NP_444260.1|refseq:XP_016861958.1|refseq:XP_016861960.1|refseq:XP_016861961.1|refseq:XP_016861962.1 - - - figure legend:Fig.2A,Supp Table S5|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-testis)|taxid:9606(Homo sapiens) - 2020/03/24 2021/11/30 rogid:ZE4tXTFi7lUCcIbCL4KHzY3a6xM9606 rogid:Wm0QbKY5KOVPytbFu5NCcT0Z1ek9606 rigid:/AFat0DrynAJ5ofEnoPSTThlxCE false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9BY14 uniprotkb:P54136 intact:EBI-12549378|ensembl:ENSP00000472769|uniprotkb:Q7L5R2|uniprotkb:Q9BPY7 intact:EBI-355482|uniprotkb:Q9BWA1|uniprotkb:B2RBS9|uniprotkb:Q53GY4|intact:EBI-28985219|ensembl:ENSP00000231572 psi-mi:tx101_human(display_long)|uniprotkb:TEX101(gene name)|psi-mi:TEX101(display_short)|uniprotkb:Cell surface receptor NYD-SP8(gene name synonym)|uniprotkb:SGRG(gene name synonym)|uniprotkb:Scleroderma-associated autoantigen(gene name synonym)|uniprotkb:Spermatogenesis-related gene protein(gene name synonym)|uniprotkb:UNQ867/PRO1884(orf name) psi-mi:syrc_human(display_long)|uniprotkb:RARS1(gene name)|psi-mi:RARS1(display_short)|uniprotkb:Arginyl-tRNA synthetase(gene name synonym)|uniprotkb:RARS(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Schiza et al. (2018) imex:IM-28077|pubmed:30097533 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-25505061|imex:IM-28077-3 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000131126(gene)|ensembl:ENST00000598265(transcript)|go:"GO:0001669"(acrosomal vesicle)|go:"GO:0002080"(acrosomal membrane)|go:"GO:0005576"(extracellular region)|go:"GO:0005886"(plasma membrane)|go:"GO:0007339"(binding of sperm to zona pellucida)|go:"GO:0009566"(fertilization)|go:"GO:0030317"(flagellated sperm motility)|go:"GO:0044853"(plasma membrane raft)|go:"GO:0046658"(anchored component of plasma membrane)|go:"GO:1901317"(regulation of flagellated sperm motility)|interpro:IPR016054(Ly-6 antigen / uPA receptor -like)|rcsb pdb:7BPR|reactome:R-HSA-163125|refseq:NP_001123483.1|refseq:NP_113639.4 refseq:NP_002878.2|ensembl:ENSG00000113643(gene)|ensembl:ENST00000231572(transcript)|go:"GO:0000049"(tRNA binding)|go:"GO:0004814"(arginine-tRNA ligase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006418"(tRNA aminoacylation for protein translation)|go:"GO:0006420"(arginyl-tRNA aminoacylation)|go:"GO:0016020"(membrane)|go:"GO:0017101"(aminoacyl-tRNA synthetase multienzyme complex)|go:"GO:0034618"(arginine binding)|go:"GO:0045296"(cadherin binding)|go:"GO:0070062"(extracellular exosome)|interpro:IPR001278(Arginyl-tRNA synthetase, class Ic)|interpro:IPR001412(Aminoacyl-tRNA synthetase, class I, conserved site)|interpro:IPR005148(Arginyl tRNA synthetase, class Ic, N-terminal)|interpro:IPR008909(DALR anticodon binding)|interpro:IPR009080(Aminoacyl-tRNA synthetase, class 1a, anticodon-binding)|interpro:IPR014729(Rossmann-like alpha/beta/alpha sandwich fold)|interpro:IPR035684|interpro:IPR036695|mint:P54136|rcsb pdb:4Q2T|rcsb pdb:4Q2X|rcsb pdb:4Q2Y|rcsb pdb:4R3Z|rcsb pdb:4ZAJ|reactome:R-HSA-2408522|reactome:R-HSA-379716|ensembl:ENSP00000231572 - - - figure legend:Fig.2A,Supp Table S5|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-testis)|taxid:9606(Homo sapiens) - 2020/03/24 2021/11/30 rogid:ZE4tXTFi7lUCcIbCL4KHzY3a6xM9606 rogid:oM9gWF1NucjgVjBFm4DcjmnQNCE9606 rigid:/AFat0DrynAJ5ofEnoPSTThlxCE false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9BY14 uniprotkb:P26440 intact:EBI-12549378|ensembl:ENSP00000472769|uniprotkb:Q7L5R2|uniprotkb:Q9BPY7 intact:EBI-2866408|uniprotkb:J3KR54|uniprotkb:Q53XZ9|uniprotkb:Q96AF6|uniprotkb:B2RCV5|uniprotkb:B3KVI7|ensembl:ENSP00000499074 psi-mi:tx101_human(display_long)|uniprotkb:TEX101(gene name)|psi-mi:TEX101(display_short)|uniprotkb:Cell surface receptor NYD-SP8(gene name synonym)|uniprotkb:SGRG(gene name synonym)|uniprotkb:Scleroderma-associated autoantigen(gene name synonym)|uniprotkb:Spermatogenesis-related gene protein(gene name synonym)|uniprotkb:UNQ867/PRO1884(orf name) psi-mi:ivd_human(display_long)|uniprotkb:IVD(gene name)|psi-mi:IVD(display_short)|uniprotkb:Butyryl-CoA dehydrogenase(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Schiza et al. (2018) imex:IM-28077|pubmed:30097533 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-25505061|imex:IM-28077-3 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000131126(gene)|ensembl:ENST00000598265(transcript)|go:"GO:0001669"(acrosomal vesicle)|go:"GO:0002080"(acrosomal membrane)|go:"GO:0005576"(extracellular region)|go:"GO:0005886"(plasma membrane)|go:"GO:0007339"(binding of sperm to zona pellucida)|go:"GO:0009566"(fertilization)|go:"GO:0030317"(flagellated sperm motility)|go:"GO:0044853"(plasma membrane raft)|go:"GO:0046658"(anchored component of plasma membrane)|go:"GO:1901317"(regulation of flagellated sperm motility)|interpro:IPR016054(Ly-6 antigen / uPA receptor -like)|rcsb pdb:7BPR|reactome:R-HSA-163125|refseq:NP_001123483.1|refseq:NP_113639.4 refseq:NP_002216.2|refseq:NP_001152980.1|ensembl:ENSG00000128928(gene)|ensembl:ENST00000651168(transcript)|go:"GO:0004085"(butyryl-CoA dehydrogenase activity)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0006552"(leucine catabolic process)|go:"GO:0008470"(isovaleryl-CoA dehydrogenase activity)|go:"GO:0009083"(branched-chain amino acid catabolic process)|go:"GO:0033539"(fatty acid beta-oxidation using acyl-CoA dehydrogenase)|go:"GO:0042802"(identical protein binding)|go:"GO:0050660"(flavin adenine dinucleotide binding)|interpro:IPR006089(Acyl-CoA dehydrogenase, conserved site)|interpro:IPR006091(Acyl-CoA dehydrogenase/oxidase, central region)|interpro:IPR009075(Acyl-CoA dehydrogenase/oxidase C-terminal)|interpro:IPR009100(Acyl-CoA dehydrogenase/oxidase, middle and N-terminal)|interpro:IPR013786(Acyl-CoA dehydrogenase/oxidase, N-terminal)|interpro:IPR034183|interpro:IPR036250|interpro:IPR037069|rcsb pdb:1IVH|reactome:R-HSA-70895 - - - figure legend:Fig.2A,Supp Table S5|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-testis)|taxid:9606(Homo sapiens) - 2020/03/24 2021/11/30 rogid:ZE4tXTFi7lUCcIbCL4KHzY3a6xM9606 rogid:GewB1Yyc2EEVepN5e1H068xpjI09606 rigid:/AFat0DrynAJ5ofEnoPSTThlxCE false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9BY14 uniprotkb:O76003 intact:EBI-12549378|ensembl:ENSP00000472769|uniprotkb:Q7L5R2|uniprotkb:Q9BPY7 intact:EBI-374781|uniprotkb:Q96CE0|uniprotkb:Q9P1B0|uniprotkb:Q9P1B1|uniprotkb:B3KMP7|uniprotkb:B3KMQ5|uniprotkb:Q5JV01|ensembl:ENSP00000330836|ensembl:ENSP00000357633|ensembl:ENSP00000435445|uniprotkb:D3DRG2 psi-mi:tx101_human(display_long)|uniprotkb:TEX101(gene name)|psi-mi:TEX101(display_short)|uniprotkb:Cell surface receptor NYD-SP8(gene name synonym)|uniprotkb:SGRG(gene name synonym)|uniprotkb:Scleroderma-associated autoantigen(gene name synonym)|uniprotkb:Spermatogenesis-related gene protein(gene name synonym)|uniprotkb:UNQ867/PRO1884(orf name) psi-mi:glrx3_human(display_long)|uniprotkb:GLRX3(gene name)|psi-mi:GLRX3(display_short)|uniprotkb:Thioredoxin-like protein 2(gene name synonym)|uniprotkb:PKC-interacting cousin of thioredoxin(gene name synonym)|uniprotkb:PKC-theta-interacting protein(gene name synonym)|uniprotkb:PICOT(gene name synonym)|uniprotkb:HUSSY-22(orf name)|uniprotkb:TXNL2(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Schiza et al. (2018) imex:IM-28077|pubmed:30097533 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-25505061|imex:IM-28077-3 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000131126(gene)|ensembl:ENST00000598265(transcript)|go:"GO:0001669"(acrosomal vesicle)|go:"GO:0002080"(acrosomal membrane)|go:"GO:0005576"(extracellular region)|go:"GO:0005886"(plasma membrane)|go:"GO:0007339"(binding of sperm to zona pellucida)|go:"GO:0009566"(fertilization)|go:"GO:0030317"(flagellated sperm motility)|go:"GO:0044853"(plasma membrane raft)|go:"GO:0046658"(anchored component of plasma membrane)|go:"GO:1901317"(regulation of flagellated sperm motility)|interpro:IPR016054(Ly-6 antigen / uPA receptor -like)|rcsb pdb:7BPR|reactome:R-HSA-163125|refseq:NP_001123483.1|refseq:NP_113639.4 ensembl:ENSG00000108010(gene)|ensembl:ENST00000331244(transcript)|ensembl:ENST00000368644(transcript)|ensembl:ENST00000481034(transcript)|go:"GO:0002026"(regulation of the force of heart contraction)|go:"GO:0003723"(RNA binding)|go:"GO:0005080"(protein kinase C binding)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0005938"(cell cortex)|go:"GO:0006879"(cellular iron ion homeostasis)|go:"GO:0010614"(negative regulation of cardiac muscle hypertrophy)|go:"GO:0030018"(Z disc)|go:"GO:0030425"(dendrite)|go:"GO:0042802"(identical protein binding)|go:"GO:0044571"([2Fe-2S] cluster assembly)|go:"GO:0046872"(metal ion binding)|go:"GO:0051536"(iron-sulfur cluster binding)|go:"GO:0097428"(protein maturation by iron-sulfur cluster transfer)|go:"GO:0097573"(glutathione oxidoreductase activity)|interpro:IPR002109(Glutaredoxin)|interpro:IPR004480(Glutaredoxin-related protein)|interpro:IPR013766(Thioredoxin domain)|interpro:IPR033658|interpro:IPR036249|mint:O76003|rcsb pdb:2DIY|rcsb pdb:2WZ9|rcsb pdb:2YAN|rcsb pdb:3ZYW|reactome:R-HSA-917937|refseq:NP_001186797.1|refseq:NP_006532.2|dip:DIP-31306N - - - figure legend:Fig.2A,Supp Table S5|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-testis)|taxid:9606(Homo sapiens) - 2020/03/24 2021/11/30 rogid:ZE4tXTFi7lUCcIbCL4KHzY3a6xM9606 rogid:iKUSt6zbNzzXSKvW+vXMq3hKsEM9606 rigid:/AFat0DrynAJ5ofEnoPSTThlxCE false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9BY14 uniprotkb:O95340 intact:EBI-12549378|ensembl:ENSP00000472769|uniprotkb:Q7L5R2|uniprotkb:Q9BPY7 intact:EBI-1053912|uniprotkb:Q9BZL2|uniprotkb:Q9P0G6|uniprotkb:Q9UHM1|uniprotkb:Q9UKD3|uniprotkb:Q9UP30|ensembl:ENSP00000354436 psi-mi:tx101_human(display_long)|uniprotkb:TEX101(gene name)|psi-mi:TEX101(display_short)|uniprotkb:Cell surface receptor NYD-SP8(gene name synonym)|uniprotkb:SGRG(gene name synonym)|uniprotkb:Scleroderma-associated autoantigen(gene name synonym)|uniprotkb:Spermatogenesis-related gene protein(gene name synonym)|uniprotkb:UNQ867/PRO1884(orf name) psi-mi:paps2_human(display_long)|uniprotkb:Sulfurylase kinase 2(gene name synonym)|uniprotkb:PAPSS2(gene name)|psi-mi:PAPSS2(display_short)|uniprotkb:ATPSK2(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Schiza et al. (2018) imex:IM-28077|pubmed:30097533 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-25505061|imex:IM-28077-3 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000131126(gene)|ensembl:ENST00000598265(transcript)|go:"GO:0001669"(acrosomal vesicle)|go:"GO:0002080"(acrosomal membrane)|go:"GO:0005576"(extracellular region)|go:"GO:0005886"(plasma membrane)|go:"GO:0007339"(binding of sperm to zona pellucida)|go:"GO:0009566"(fertilization)|go:"GO:0030317"(flagellated sperm motility)|go:"GO:0044853"(plasma membrane raft)|go:"GO:0046658"(anchored component of plasma membrane)|go:"GO:1901317"(regulation of flagellated sperm motility)|interpro:IPR016054(Ly-6 antigen / uPA receptor -like)|rcsb pdb:7BPR|reactome:R-HSA-163125|refseq:NP_001123483.1|refseq:NP_113639.4 refseq:NP_001015880.1|refseq:NP_004661.2|ensembl:ENSG00000198682(gene)|ensembl:ENST00000361175(transcript)|go:"GO:0000103"(sulfate assimilation)|go:"GO:0001501"(skeletal system development)|go:"GO:0004020"(adenylylsulfate kinase activity)|go:"GO:0004781"("sulfate adenylyltransferase (ATP) activity")|go:"GO:0005524"(ATP binding)|go:"GO:0005829"(cytosol)|go:"GO:0016779"(nucleotidyltransferase activity)|go:"GO:0050428"(3'-phosphoadenosine 5'-phosphosulfate biosynthetic process)|interpro:IPR002650(ATP-sulphurylase)|interpro:IPR002891(Adenylylsulphate kinase, C-terminal)|interpro:IPR014729(Rossmann-like alpha/beta/alpha sandwich fold)|interpro:IPR015947(PUA-like)|interpro:IPR024951|interpro:IPR025980|interpro:IPR027417|rcsb pdb:2AX4|reactome:R-HSA-174362|reactome:R-HSA-2408550|reactome:R-HSA-3560796 - - - figure legend:Fig.2A,Supp Table S5|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-testis)|taxid:9606(Homo sapiens) - 2020/03/24 2021/11/30 rogid:ZE4tXTFi7lUCcIbCL4KHzY3a6xM9606 rogid:0t32V/kBypJ6YKgkyxAxC3RGmeU9606 rigid:/AFat0DrynAJ5ofEnoPSTThlxCE false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9BY14 uniprotkb:Q03135 intact:EBI-12549378|ensembl:ENSP00000472769|uniprotkb:Q7L5R2|uniprotkb:Q9BPY7 intact:EBI-603614|ensembl:ENSP00000339191|uniprotkb:Q9UGP1|uniprotkb:Q9UNG1|uniprotkb:Q9UQH6 psi-mi:tx101_human(display_long)|uniprotkb:TEX101(gene name)|psi-mi:TEX101(display_short)|uniprotkb:Cell surface receptor NYD-SP8(gene name synonym)|uniprotkb:SGRG(gene name synonym)|uniprotkb:Scleroderma-associated autoantigen(gene name synonym)|uniprotkb:Spermatogenesis-related gene protein(gene name synonym)|uniprotkb:UNQ867/PRO1884(orf name) psi-mi:cav1_human(display_long)|uniprotkb:CAV1(gene name)|psi-mi:CAV1(display_short)|uniprotkb:CAV(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Schiza et al. (2018) imex:IM-28077|pubmed:30097533 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-25505061|imex:IM-28077-3 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000131126(gene)|ensembl:ENST00000598265(transcript)|go:"GO:0001669"(acrosomal vesicle)|go:"GO:0002080"(acrosomal membrane)|go:"GO:0005576"(extracellular region)|go:"GO:0005886"(plasma membrane)|go:"GO:0007339"(binding of sperm to zona pellucida)|go:"GO:0009566"(fertilization)|go:"GO:0030317"(flagellated sperm motility)|go:"GO:0044853"(plasma membrane raft)|go:"GO:0046658"(anchored component of plasma membrane)|go:"GO:1901317"(regulation of flagellated sperm motility)|interpro:IPR016054(Ly-6 antigen / uPA receptor -like)|rcsb pdb:7BPR|reactome:R-HSA-163125|refseq:NP_001123483.1|refseq:NP_113639.4 go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0031623"(receptor internalization)|go:"GO:0031901"(early endosome membrane)|go:"GO:0032091"(negative regulation of protein binding)|go:"GO:0032092"(positive regulation of protein binding)|go:"GO:0032507"(maintenance of protein location in cell)|go:"GO:0032570"(response to progesterone)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033137"(negative regulation of peptidyl-serine phosphorylation)|go:"GO:0033138"(positive regulation of peptidyl-serine phosphorylation)|go:"GO:0033484"(nitric oxide homeostasis)|go:"GO:0034141"(positive regulation of toll-like receptor 3 signaling pathway)|go:"GO:0038016"(insulin receptor internalization)|go:"GO:0042310"(vasoconstriction)|go:"GO:0042532"(negative regulation of tyrosine phosphorylation of STAT protein)|go:"GO:0042632"(cholesterol homeostasis)|go:"GO:0042802"(identical protein binding)|go:"GO:0043085"(positive regulation of catalytic activity)|go:"GO:0043407"(negative regulation of MAP kinase activity)|go:"GO:0043409"(negative regulation of MAPK cascade)|go:"GO:0043627"(response to estrogen)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0044860"(protein localization to plasma membrane raft)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045019"(negative regulation of nitric oxide biosynthetic process)|go:"GO:0045121"(membrane raft)|go:"GO:0045907"(positive regulation of vasoconstriction)|go:"GO:0046426"(negative regulation of receptor signaling pathway via JAK-STAT)|go:"GO:0031398"(positive regulation of protein ubiquitination)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0048550"(negative regulation of pinocytosis)|go:"GO:0050998"(nitric-oxide synthase binding)|go:"GO:0051001"(negative regulation of nitric-oxide synthase activity)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|go:"GO:0051117"(ATPase binding)|go:"GO:0051480"(regulation of cytosolic calcium ion concentration)|go:"GO:0051592"(response to calcium ion)|go:"GO:0051899"(membrane depolarization)|go:"GO:0052547"(regulation of peptidase activity)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0055074"(calcium ion homeostasis)|go:"GO:0060056"(mammary gland involution)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0060355"(positive regulation of cell adhesion molecule production)|go:"GO:0060546"(negative regulation of necroptotic process)|go:"GO:0061099"(negative regulation of protein tyrosine kinase activity)|go:"GO:0070320"(inward rectifier potassium channel inhibitor activity)|go:"GO:0070836"(caveola assembly)|go:"GO:0071360"(cellular response to exogenous dsRNA)|go:"GO:0071375"(cellular response to peptide hormone stimulus)|go:"GO:0071455"(cellular response to hyperoxia)|go:"GO:0071560"(cellular response to transforming growth factor beta stimulus)|go:"GO:0071711"(basement membrane organization)|go:"GO:0072584"(caveolin-mediated endocytosis)|go:"GO:0086091"(regulation of heart rate by cardiac conduction)|go:"GO:0086098"(angiotensin-activated signaling pathway involved in heart process)|go:"GO:1903361"(protein localization to basolateral plasma membrane)|go:"GO:1903598"(positive regulation of gap junction assembly)|go:"GO:1903609"(negative regulation of inward rectifier potassium channel activity)|go:"GO:2000286"(receptor internalization involved in canonical Wnt signaling pathway)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:2000535"(regulation of entry of bacterium into host cell)|go:"GO:2000811"(negative regulation of anoikis)|go:"GO:0090263"(positive regulation of canonical Wnt signaling pathway)|go:"GO:2001238"(positive regulation of extrinsic apoptotic signaling pathway)|go:"GO:2001244"(positive regulation of intrinsic apoptotic signaling pathway)|interpro:IPR001612(Caveolin)|interpro:IPR015504(Caveolin-1)|go:"GO:0097190"(apoptotic signaling pathway)|go:"GO:0098903"(regulation of membrane repolarization during action potential)|interpro:IPR018361|mint:Q03135|go:"GO:0098909"(regulation of cardiac muscle cell action potential involved in regulation of contraction)|reactome:R-HSA-163560|go:"GO:0098911"(regulation of ventricular cardiac muscle cell action potential)|go:"GO:0120162"(positive regulation of cold-induced thermogenesis)|reactome:R-HSA-203615|reactome:R-HSA-203641|reactome:R-HSA-210991|reactome:R-HSA-4641262|go:"GO:1900027"(regulation of ruffle assembly)|go:"GO:1900085"(negative regulation of peptidyl-tyrosine autophosphorylation)|go:"GO:1901380"(negative regulation of potassium ion transmembrane transport)|go:"GO:1901844"(regulation of cell communication by electrical coupling involved in cardiac conduction)|go:"GO:1903071"(positive regulation of ER-associated ubiquitin-dependent protein catabolic process)|reactome:R-HSA-5218920|reactome:R-HSA-8980692|reactome:R-HSA-9009391|reactome:R-HSA-9013026|reactome:R-HSA-9013106|reactome:R-HSA-9013148|reactome:R-HSA-9013149|reactome:R-HSA-9013404|reactome:R-HSA-9013405|reactome:R-HSA-9013406|reactome:R-HSA-9013407|reactome:R-HSA-9013408|reactome:R-HSA-9013409|reactome:R-HSA-9035034|reactome:R-HSA-9013423|reactome:R-HSA-9617828|reactome:R-HSA-9696264|reactome:R-HSA-9696270|reactome:R-HSA-9696273|ensembl:ENST00000341049(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000139"(Golgi membrane)|ensembl:ENSG00000105974(gene)|go:"GO:0001525"(angiogenesis)|go:"GO:0001570"(vasculogenesis)|go:"GO:0001666"(response to hypoxia)|go:"GO:0001937"(negative regulation of endothelial cell proliferation)|go:"GO:0001960"(negative regulation of cytokine-mediated signaling pathway)|go:"GO:0002080"(acrosomal membrane)|go:"GO:0002095"(caveolar macromolecular signaling complex)|go:"GO:0002931"(response to ischemia)|go:"GO:0003057"(regulation of the force of heart contraction by chemical signal)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005113"(patched binding)|go:"GO:0005768"(endosome)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005811"(lipid droplet)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0005901"(caveola)|go:"GO:0005925"(focal adhesion)|go:"GO:0005929"(cilium)|go:"GO:0005938"(cell cortex)|go:"GO:0006641"(triglyceride metabolic process)|go:"GO:0006816"(calcium ion transport)|go:"GO:0006940"(regulation of smooth muscle contraction)|go:"GO:0007519"(skeletal muscle tissue development)|go:"GO:0007595"(lactation)|go:"GO:0008104"(protein localization)|go:"GO:0009267"(cellular response to starvation)|go:"GO:0009617"(response to bacterium)|go:"GO:0010524"(positive regulation of calcium ion transport into cytosol)|go:"GO:0010608"(posttranscriptional regulation of gene expression)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010875"(positive regulation of cholesterol efflux)|go:"GO:0015031"(protein transport)|go:"GO:0015485"(cholesterol binding)|go:"GO:0016020"(membrane)|go:"GO:0016050"(vesicle organization)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0016504"(peptidase activator activity)|go:"GO:0019065"(receptor-mediated endocytosis of virus by host cell)|go:"GO:0019217"(regulation of fatty acid metabolic process)|go:"GO:0019899"(enzyme binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0019915"(lipid storage)|go:"GO:0030154"(cell differentiation)|go:"GO:0030193"(regulation of blood coagulation)|go:"GO:0030301"(cholesterol transport)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0030512"(negative regulation of transforming growth factor beta receptor signaling pathway)|go:"GO:0030514"(negative regulation of BMP signaling pathway)|go:"GO:0030666"(endocytic vesicle membrane)|go:"GO:0030674"(protein-macromolecule adaptor activity)|go:"GO:0030857"(negative regulation of epithelial cell differentiation)|go:"GO:0030879"(mammary gland development)|go:"GO:0031267"(small GTPase binding)|go:"GO:0031295"(T cell costimulation)|go:"GO:0031397"(negative regulation of protein ubiquitination)|go:"GO:0006874"(cellular calcium ion homeostasis)|refseq:NP_001744.2|dip:DIP-5960N - - - figure legend:Fig.2A,Supp Table S5|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-testis)|taxid:9606(Homo sapiens) - 2020/03/24 2021/11/30 rogid:ZE4tXTFi7lUCcIbCL4KHzY3a6xM9606 rogid:+JhGp5YmhT3JLeTgHHBTHu9r34c9606 rigid:/AFat0DrynAJ5ofEnoPSTThlxCE false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9BY14 uniprotkb:P61221 intact:EBI-12549378|ensembl:ENSP00000472769|uniprotkb:Q7L5R2|uniprotkb:Q9BPY7 intact:EBI-2510446|ensembl:ENSP00000296577|uniprotkb:Q6NR76|uniprotkb:O88793|uniprotkb:Q13181|uniprotkb:Q99K66|uniprotkb:Q13864|uniprotkb:Q96AL0|uniprotkb:Q96B10 psi-mi:tx101_human(display_long)|uniprotkb:TEX101(gene name)|psi-mi:TEX101(display_short)|uniprotkb:Cell surface receptor NYD-SP8(gene name synonym)|uniprotkb:SGRG(gene name synonym)|uniprotkb:Scleroderma-associated autoantigen(gene name synonym)|uniprotkb:Spermatogenesis-related gene protein(gene name synonym)|uniprotkb:UNQ867/PRO1884(orf name) psi-mi:abce1_human(display_long)|uniprotkb:ABCE1(gene name)|psi-mi:ABCE1(display_short)|uniprotkb:RLI(gene name synonym)|uniprotkb:RNASEL1(gene name synonym)|uniprotkb:RNASELI(gene name synonym)|uniprotkb:RNS4I(gene name synonym)|uniprotkb:RNase L inhibitor(gene name synonym)|uniprotkb:Ribonuclease 4 inhibitor(gene name synonym)|uniprotkb:2'-5'-oligoadenylate-binding protein(gene name synonym)|uniprotkb:HuHP68(gene name synonym)|uniprotkb:OK/SW-cl.40(orf name) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Schiza et al. (2018) imex:IM-28077|pubmed:30097533 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-25505061|imex:IM-28077-3 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000131126(gene)|ensembl:ENST00000598265(transcript)|go:"GO:0001669"(acrosomal vesicle)|go:"GO:0002080"(acrosomal membrane)|go:"GO:0005576"(extracellular region)|go:"GO:0005886"(plasma membrane)|go:"GO:0007339"(binding of sperm to zona pellucida)|go:"GO:0009566"(fertilization)|go:"GO:0030317"(flagellated sperm motility)|go:"GO:0044853"(plasma membrane raft)|go:"GO:0046658"(anchored component of plasma membrane)|go:"GO:1901317"(regulation of flagellated sperm motility)|interpro:IPR016054(Ly-6 antigen / uPA receptor -like)|rcsb pdb:7BPR|reactome:R-HSA-163125|refseq:NP_001123483.1|refseq:NP_113639.4 ensembl:ENSG00000164163(gene)|ensembl:ENST00000296577(transcript)|go:"GO:0000054"(ribosomal subunit export from nucleus)|go:"GO:0005506"(iron ion binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0005829"(cytosol)|go:"GO:0006413"(translational initiation)|go:"GO:0006415"(translational termination)|go:"GO:0006417"(regulation of translation)|go:"GO:0016020"(membrane)|go:"GO:0042626"(ATPase-coupled transmembrane transporter activity)|go:"GO:0043024"(ribosomal small subunit binding)|go:"GO:0051539"(4 iron, 4 sulfur cluster binding)|go:"GO:0060698"(endoribonuclease inhibitor activity)|go:"GO:0060702"(negative regulation of endoribonuclease activity)|interpro:IPR003439(ABC transporter-like)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR007209(Possible metal-binding region in RNase L inhibitor, RLI)|interpro:IPR013283(ABC transporter, ABCE)|interpro:IPR017871|interpro:IPR017896|interpro:IPR017900|interpro:IPR027417|interpro:IPR034348|mint:P61221|rcsb pdb:6ZME|rcsb pdb:6ZVJ|rcsb pdb:7A09|reactome:R-HSA-8983711|reactome:R-HSA-909733|refseq:NP_001035809.1|refseq:NP_002931.2 - - - figure legend:Fig.2A,Supp Table S5|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-testis)|taxid:9606(Homo sapiens) - 2020/03/24 2021/11/30 rogid:ZE4tXTFi7lUCcIbCL4KHzY3a6xM9606 rogid:+6ykpRtI4p94M3TuoTzFBvdCsC09606 rigid:/AFat0DrynAJ5ofEnoPSTThlxCE false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9BY14 uniprotkb:O43681 intact:EBI-12549378|ensembl:ENSP00000472769|uniprotkb:Q7L5R2|uniprotkb:Q9BPY7 intact:EBI-2515857|ensembl:ENSP00000349887|ensembl:ENSP00000466379|uniprotkb:Q53FC6|uniprotkb:A8K740|uniprotkb:A6NHP8|uniprotkb:Q92849|intact:EBI-2818109 psi-mi:tx101_human(display_long)|uniprotkb:TEX101(gene name)|psi-mi:TEX101(display_short)|uniprotkb:Cell surface receptor NYD-SP8(gene name synonym)|uniprotkb:SGRG(gene name synonym)|uniprotkb:Scleroderma-associated autoantigen(gene name synonym)|uniprotkb:Spermatogenesis-related gene protein(gene name synonym)|uniprotkb:UNQ867/PRO1884(orf name) psi-mi:get3_human(display_long)|uniprotkb:GET3(gene name)|psi-mi:GET3(display_short)|uniprotkb:ARSA(gene name synonym)|uniprotkb:ASNA1(gene name synonym)|uniprotkb:Arsenical pump-driving ATPase(gene name synonym)|uniprotkb:Arsenite-stimulated ATPase(gene name synonym)|uniprotkb:Guided entry of tail-anchored proteins factor 3, ATPase(gene name synonym)|uniprotkb:TRC40(gene name synonym)|uniprotkb:Transmembrane domain recognition complex 40 kDa ATPase subunit(gene name synonym)|uniprotkb:hARSA-I(gene name synonym)|uniprotkb:hASNA-I(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Schiza et al. (2018) imex:IM-28077|pubmed:30097533 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-25505061|imex:IM-28077-3 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000131126(gene)|ensembl:ENST00000598265(transcript)|go:"GO:0001669"(acrosomal vesicle)|go:"GO:0002080"(acrosomal membrane)|go:"GO:0005576"(extracellular region)|go:"GO:0005886"(plasma membrane)|go:"GO:0007339"(binding of sperm to zona pellucida)|go:"GO:0009566"(fertilization)|go:"GO:0030317"(flagellated sperm motility)|go:"GO:0044853"(plasma membrane raft)|go:"GO:0046658"(anchored component of plasma membrane)|go:"GO:1901317"(regulation of flagellated sperm motility)|interpro:IPR016054(Ly-6 antigen / uPA receptor -like)|rcsb pdb:7BPR|reactome:R-HSA-163125|refseq:NP_001123483.1|refseq:NP_113639.4 ensembl:ENSG00000198356(gene)|ensembl:ENST00000357332(transcript)|ensembl:ENST00000591090(transcript)|go:"GO:0005524"(ATP binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006620"(posttranslational protein targeting to endoplasmic reticulum membrane)|go:"GO:0015105"(arsenite transmembrane transporter activity)|go:"GO:0016787"(hydrolase activity)|go:"GO:0043529"(GET complex)|go:"GO:0046872"(metal ion binding)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071816"(tail-anchored membrane protein insertion into ER membrane)|interpro:IPR016300(Arsenite-transporting ATPase)|interpro:IPR025723|interpro:IPR027417|interpro:IPR027542|mint:O43681|rcsb pdb:6SO5|reactome:R-HSA-9609523|refseq:NP_004308.2 - - - figure legend:Fig.2A,Supp Table S5|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-testis)|taxid:9606(Homo sapiens) - 2020/03/24 2021/11/30 rogid:ZE4tXTFi7lUCcIbCL4KHzY3a6xM9606 rogid:j2jKZb3MH8Bd3hnoQhDO6bjbyxI9606 rigid:/AFat0DrynAJ5ofEnoPSTThlxCE false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9BY14 uniprotkb:P63208 intact:EBI-12549378|ensembl:ENSP00000472769|uniprotkb:Q7L5R2|uniprotkb:Q9BPY7 intact:EBI-307486|uniprotkb:P34991|uniprotkb:Q8TAY2|uniprotkb:D3DQ97|uniprotkb:D3DQ98|ensembl:ENSP00000231487|ensembl:ENSP00000429686|ensembl:ENSP00000429961 psi-mi:tx101_human(display_long)|uniprotkb:TEX101(gene name)|psi-mi:TEX101(display_short)|uniprotkb:Cell surface receptor NYD-SP8(gene name synonym)|uniprotkb:SGRG(gene name synonym)|uniprotkb:Scleroderma-associated autoantigen(gene name synonym)|uniprotkb:Spermatogenesis-related gene protein(gene name synonym)|uniprotkb:UNQ867/PRO1884(orf name) psi-mi:skp1_human(display_long)|uniprotkb:SKP1(gene name)|psi-mi:SKP1(display_short)|uniprotkb:EMC19(gene name synonym)|uniprotkb:OCP2(gene name synonym)|uniprotkb:SKP1A(gene name synonym)|uniprotkb:TCEB1L(gene name synonym)|uniprotkb:Cyclin-A/CDK2-associated protein p19(gene name synonym)|uniprotkb:p19skp1(gene name synonym)|uniprotkb:RNA polymerase II elongation factor-like protein(gene name synonym)|uniprotkb:Organ of Corti protein 2(gene name synonym)|uniprotkb:Organ of Corti protein II(gene name synonym)|uniprotkb:SIII(gene name synonym)|uniprotkb:Transcription elongation factor B polypeptide 1-like(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Schiza et al. (2018) imex:IM-28077|pubmed:30097533 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-25505061|imex:IM-28077-3 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000131126(gene)|ensembl:ENST00000598265(transcript)|go:"GO:0001669"(acrosomal vesicle)|go:"GO:0002080"(acrosomal membrane)|go:"GO:0005576"(extracellular region)|go:"GO:0005886"(plasma membrane)|go:"GO:0007339"(binding of sperm to zona pellucida)|go:"GO:0009566"(fertilization)|go:"GO:0030317"(flagellated sperm motility)|go:"GO:0044853"(plasma membrane raft)|go:"GO:0046658"(anchored component of plasma membrane)|go:"GO:1901317"(regulation of flagellated sperm motility)|interpro:IPR016054(Ly-6 antigen / uPA receptor -like)|rcsb pdb:7BPR|reactome:R-HSA-163125|refseq:NP_001123483.1|refseq:NP_113639.4 reactome:R-HSA-5607764|reactome:R-HSA-5610780|reactome:R-HSA-5610783|reactome:R-HSA-5610785|reactome:R-HSA-5676590|reactome:R-HSA-5684264|reactome:R-HSA-1170546|reactome:R-HSA-174113|reactome:R-HSA-180534|reactome:R-HSA-187577|reactome:R-HSA-68949|reactome:R-HSA-69231|reactome:R-HSA-8854050|reactome:R-HSA-8939902|reactome:R-HSA-8951664|reactome:R-HSA-9020702|reactome:R-HSA-917937|reactome:R-HSA-9604323|reactome:R-HSA-9708530|reactome:R-HSA-983168|reactome:R-HSA-195253|reactome:R-HSA-202424|reactome:R-HSA-2122947|reactome:R-HSA-2565942|reactome:R-HSA-2644606|reactome:R-HSA-2644607|reactome:R-HSA-2871837|reactome:R-HSA-2894862|reactome:R-HSA-400253|reactome:R-HSA-5607761|refseq:NP_008861.2|refseq:NP_733779.1|ensembl:ENSG00000113558(gene)|ensembl:ENST00000353411(transcript)|ensembl:ENST00000522855(transcript)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|ensembl:ENST00000517625(transcript)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0019005"(SCF ubiquitin ligase complex)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0031146"(SCF-dependent proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0031467"(Cul7-RING ubiquitin ligase complex)|go:"GO:0035518"(histone H2A monoubiquitination)|go:"GO:0051457"(maintenance of protein location in nucleus)|go:"GO:0070936"(protein K48-linked ubiquitination)|go:"GO:0097602"(cullin family protein binding)|go:"GO:1904668"(positive regulation of ubiquitin protein ligase activity)|go:"GO:1990444"(F-box domain binding)|go:"GO:1990756"(ubiquitin ligase-substrate adaptor activity)|interpro:IPR001232(SKP1 component)|interpro:IPR011333(BTB/POZ fold)|interpro:IPR016072(SKP1 component, dimerisation)|interpro:IPR016073(SKP1 component, POZ)|interpro:IPR016897(E3 ubiquitin ligase, SCF complex, Skp subunit)|interpro:IPR036296|mint:P63208|rcsb pdb:1FQV|rcsb pdb:1FS1|rcsb pdb:1FS2|rcsb pdb:1LDK|rcsb pdb:1P22|rcsb pdb:2ASS|rcsb pdb:2AST|rcsb pdb:2E31|rcsb pdb:2E32|rcsb pdb:2OVP|rcsb pdb:2OVQ|rcsb pdb:2OVR|rcsb pdb:3L2O|rcsb pdb:3WSO|rcsb pdb:4I6J|rcsb pdb:5IBK|rcsb pdb:5JH5|rcsb pdb:5K35|rcsb pdb:5V4B|rcsb pdb:5VZT|rcsb pdb:5VZU|rcsb pdb:5XYL|rcsb pdb:6BVA|rcsb pdb:6BYH|rcsb pdb:6C16|rcsb pdb:6M90|rcsb pdb:6M91|rcsb pdb:6M92|rcsb pdb:6M93|rcsb pdb:6M94|rcsb pdb:6O60|rcsb pdb:6TTU|rcsb pdb:6VCD|rcsb pdb:6W66|rcsb pdb:6WCQ|rcsb pdb:6WNX|rcsb pdb:7B5L|rcsb pdb:7B5M|rcsb pdb:7B5R|reactome:R-HSA-1169091|dip:DIP-31606N - - - figure legend:Fig.2A,Supp Table S5|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-testis)|taxid:9606(Homo sapiens) - 2020/03/24 2021/11/30 rogid:ZE4tXTFi7lUCcIbCL4KHzY3a6xM9606 rogid:0U28UYW/heL+7UJO5f3h8Wq+Ud09606 rigid:/AFat0DrynAJ5ofEnoPSTThlxCE false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9BY14 uniprotkb:P13010 intact:EBI-12549378|ensembl:ENSP00000472769|uniprotkb:Q7L5R2|uniprotkb:Q9BPY7 intact:EBI-357997|uniprotkb:A8K3X5|uniprotkb:Q0Z7V0|uniprotkb:Q53HH7|uniprotkb:Q7M4N0|uniprotkb:Q4VBQ5|uniprotkb:Q9UCQ0|uniprotkb:Q9UCQ1|ensembl:ENSP00000375977|ensembl:ENSP00000375978 psi-mi:tx101_human(display_long)|uniprotkb:TEX101(gene name)|psi-mi:TEX101(display_short)|uniprotkb:Cell surface receptor NYD-SP8(gene name synonym)|uniprotkb:SGRG(gene name synonym)|uniprotkb:Scleroderma-associated autoantigen(gene name synonym)|uniprotkb:Spermatogenesis-related gene protein(gene name synonym)|uniprotkb:UNQ867/PRO1884(orf name) psi-mi:xrcc5_human(display_long)|uniprotkb:XRCC5(gene name)|psi-mi:XRCC5(display_short)|uniprotkb:G22P2(gene name synonym)|uniprotkb:ATP-dependent DNA helicase II 80 kDa subunit(gene name synonym)|uniprotkb:Lupus Ku autoantigen protein p86(gene name synonym)|uniprotkb:86 kDa subunit of Ku antigen(gene name synonym)|uniprotkb:Ku86(gene name synonym)|uniprotkb:Ku80(gene name synonym)|uniprotkb:Thyroid-lupus autoantigen(gene name synonym)|uniprotkb:CTC box-binding factor 85 kDa subunit(gene name synonym)|uniprotkb:Nuclear factor IV(gene name synonym)|uniprotkb:DNA repair protein XRCC5(gene name synonym)|uniprotkb:"X-ray repair complementing defective repair in Chinese hamster cells 5 (double-strand-break rejoining)"(gene name synonym)|uniprotkb:ATP-dependent DNA helicase 2 subunit 2(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Schiza et al. (2018) imex:IM-28077|pubmed:30097533 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-25505061|imex:IM-28077-3 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000131126(gene)|ensembl:ENST00000598265(transcript)|go:"GO:0001669"(acrosomal vesicle)|go:"GO:0002080"(acrosomal membrane)|go:"GO:0005576"(extracellular region)|go:"GO:0005886"(plasma membrane)|go:"GO:0007339"(binding of sperm to zona pellucida)|go:"GO:0009566"(fertilization)|go:"GO:0030317"(flagellated sperm motility)|go:"GO:0044853"(plasma membrane raft)|go:"GO:0046658"(anchored component of plasma membrane)|go:"GO:1901317"(regulation of flagellated sperm motility)|interpro:IPR016054(Ly-6 antigen / uPA receptor -like)|rcsb pdb:7BPR|reactome:R-HSA-163125|refseq:NP_001123483.1|refseq:NP_113639.4 refseq:NP_066964.1|ensembl:ENST00000392132(transcript)|ensembl:ENSG00000079246(gene)|dip:DIP-31379N|go:"GO:0043085"(positive regulation of catalytic activity)|go:"GO:0043564"("Ku70:Ku80 complex")|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045027"(DNA end binding)|go:"GO:0045087"(innate immune response)|go:"GO:0045860"(positive regulation of protein kinase activity)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0048660"(regulation of smooth muscle cell proliferation)|go:"GO:0050769"(positive regulation of neurogenesis)|go:"GO:0051973"(positive regulation of telomerase activity)|go:"GO:0060218"(hematopoietic stem cell differentiation)|go:"GO:0070198"(protein localization to chromosome, telomeric region)|go:"GO:0070419"(nonhomologous end joining complex)|go:"GO:0071398"(cellular response to fatty acid)|go:"GO:0071475"(cellular hyperosmotic salinity response)|go:"GO:0071480"(cellular response to gamma radiation)|go:"GO:0071481"(cellular response to X-ray)|go:"GO:0090734"(site of DNA damage)|go:"GO:0008094"(ATP-dependent activity, acting on DNA)|go:"GO:0008283"(cell population proliferation)|go:"GO:0016020"(membrane)|go:"GO:0016787"(hydrolase activity)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032040"(small-subunit processome)|go:"GO:0032204"(regulation of telomere maintenance)|go:"GO:0032212"(positive regulation of telomere maintenance via telomerase)|go:"GO:0032991"(protein-containing complex)|go:"GO:0032993"(protein-DNA complex)|go:"GO:0034462"(small-subunit processome assembly)|go:"GO:0034511"(U3 snoRNA binding)|go:"GO:0034774"(secretory granule lumen)|go:"GO:0042162"(telomeric DNA binding)|go:"GO:0042493"|ensembl:ENST00000392133(transcript)|go:"GO:0000723"(telomere maintenance)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0000783"(nuclear telomere cap complex)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0002218"(activation of innate immune response)|go:"GO:0003677"(DNA binding)|go:"GO:0003678"(DNA helicase activity)|go:"GO:0003684"(damaged DNA binding)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006302"(double-strand break repair)|go:"GO:0006303"(double-strand break repair via nonhomologous end joining)|go:"GO:0006310"(DNA recombination)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0007420"(brain development)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008047"(enzyme activator activity)|go:"GO:1904430"(negative regulation of t-circle formation)|go:"GO:1990830"(cellular response to leukemia inhibitory factor)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR002035(von Willebrand factor, type A)|interpro:IPR005160(Ku70/Ku80 C-terminal arm)|interpro:IPR005161(Ku70/Ku80, N-terminal alpha/beta)|interpro:IPR006164(DNA helicase, ATP-dependent, Ku type)|interpro:IPR014893(Ku, C-terminal)|interpro:IPR016194(Spen Paralogue and Orthologue C-terminal-like)|interpro:IPR024193|interpro:IPR036465|interpro:IPR036494|mint:P13010|rcsb pdb:1JEQ|rcsb pdb:1JEY|rcsb pdb:1Q2Z|rcsb pdb:1RW2|rcsb pdb:3RZ9|rcsb pdb:5Y3R|rcsb pdb:6ERF|rcsb pdb:6ERG|rcsb pdb:6ERH|rcsb pdb:6ZH6|rcsb pdb:6ZHA|rcsb pdb:6ZHE|rcsb pdb:7AXZ|rcsb pdb:7K0Y|rcsb pdb:7K17|rcsb pdb:7K1J|rcsb pdb:7K1K|rcsb pdb:7K1N|rcsb pdb:7LSY|rcsb pdb:7LT3|reactome:R-HSA-164843|reactome:R-HSA-1834949|reactome:R-HSA-3270619|reactome:R-HSA-5693571|reactome:R-HSA-6798695 - - - figure legend:Fig.2A,Supp Table S5|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-testis)|taxid:9606(Homo sapiens) - 2020/03/24 2021/11/30 rogid:ZE4tXTFi7lUCcIbCL4KHzY3a6xM9606 rogid:ZPJCWdA2YqOqXgfSRfDQCoEsyoA9606 rigid:/AFat0DrynAJ5ofEnoPSTThlxCE false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9BY14 uniprotkb:P23229 intact:EBI-12549378|ensembl:ENSP00000472769|uniprotkb:Q7L5R2|uniprotkb:Q9BPY7 intact:EBI-2436548|uniprotkb:Q9UCT1|uniprotkb:B2RMU9|uniprotkb:B4DG69|uniprotkb:B4DKB8|uniprotkb:Q08443|uniprotkb:Q0MRC7|uniprotkb:Q14646|uniprotkb:Q16508|uniprotkb:Q53RX7|uniprotkb:Q59HB7|uniprotkb:Q86VL6|uniprotkb:Q9UN03|uniprotkb:G5E9H1|uniprotkb:C4AM96|ensembl:ENSP00000406694 psi-mi:tx101_human(display_long)|uniprotkb:TEX101(gene name)|psi-mi:TEX101(display_short)|uniprotkb:Cell surface receptor NYD-SP8(gene name synonym)|uniprotkb:SGRG(gene name synonym)|uniprotkb:Scleroderma-associated autoantigen(gene name synonym)|uniprotkb:Spermatogenesis-related gene protein(gene name synonym)|uniprotkb:UNQ867/PRO1884(orf name) psi-mi:ita6_human(display_long)|uniprotkb:ITGA6(gene name)|psi-mi:ITGA6(display_short)|uniprotkb:VLA-6(gene name synonym)|uniprotkb:CD49 antigen-like family member F(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Schiza et al. (2018) imex:IM-28077|pubmed:30097533 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-25505061|imex:IM-28077-3 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000131126(gene)|ensembl:ENST00000598265(transcript)|go:"GO:0001669"(acrosomal vesicle)|go:"GO:0002080"(acrosomal membrane)|go:"GO:0005576"(extracellular region)|go:"GO:0005886"(plasma membrane)|go:"GO:0007339"(binding of sperm to zona pellucida)|go:"GO:0009566"(fertilization)|go:"GO:0030317"(flagellated sperm motility)|go:"GO:0044853"(plasma membrane raft)|go:"GO:0046658"(anchored component of plasma membrane)|go:"GO:1901317"(regulation of flagellated sperm motility)|interpro:IPR016054(Ly-6 antigen / uPA receptor -like)|rcsb pdb:7BPR|reactome:R-HSA-163125|refseq:NP_001123483.1|refseq:NP_113639.4 refseq:NP_000201.2|refseq:NP_001073286.1|refseq:NP_001303235.1|ensembl:ENSG00000091409(gene)|ensembl:ENST00000442250(transcript)|go:"GO:0005886"(plasma membrane)|go:"GO:0005912"(adherens junction)|go:"GO:0005925"(focal adhesion)|go:"GO:0007044"(cell-substrate junction assembly)|go:"GO:0007229"(integrin-mediated signaling pathway)|go:"GO:0009986"(cell surface)|go:"GO:0010668"(ectodermal cell differentiation)|go:"GO:0010811"(positive regulation of cell-substrate adhesion)|go:"GO:0010976"(positive regulation of neuron projection development)|go:"GO:0030175"(filopodium)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0031589"(cell-substrate adhesion)|go:"GO:0031994"(insulin-like growth factor I binding)|go:"GO:0034676"(integrin alpha6-beta4 complex)|go:"GO:0035878"(nail development)|go:"GO:0038132"(neuregulin binding)|go:"GO:0042327"(positive regulation of phosphorylation)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043236"(laminin binding)|go:"GO:0043547"(positive regulation of GTPase activity)|go:"GO:0043589"(skin morphogenesis)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045296"(cadherin binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|go:"GO:0071407"(cellular response to organic cyclic compound)|go:"GO:0098609"(cell-cell adhesion)|go:"GO:2001237"(negative regulation of extrinsic apoptotic signaling pathway)|interpro:IPR000413(Integrins alpha chain)|interpro:IPR013517(FG-GAP)|interpro:IPR013519(Integrin alpha beta-propellor)|interpro:IPR013649(Integrin alpha-2)|interpro:IPR018184|interpro:IPR032695|mint:P23229|rcsb pdb:7CEB|rcsb pdb:7CEC|reactome:R-HSA-2022090|reactome:R-HSA-210991|reactome:R-HSA-216083|reactome:R-HSA-3000157|reactome:R-HSA-3000170|reactome:R-HSA-446107 - - - figure legend:Fig.2A,Supp Table S5|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-testis)|taxid:9606(Homo sapiens) - 2020/03/24 2021/11/30 rogid:ZE4tXTFi7lUCcIbCL4KHzY3a6xM9606 rogid:YyoW/gnP6QH8w7M9UxzVxMTkpOg9606 rigid:/AFat0DrynAJ5ofEnoPSTThlxCE false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9BY14 uniprotkb:O60831 intact:EBI-12549378|ensembl:ENSP00000472769|uniprotkb:Q7L5R2|uniprotkb:Q9BPY7 intact:EBI-2506064|ensembl:ENSP00000451962|uniprotkb:B2RD20 psi-mi:tx101_human(display_long)|uniprotkb:TEX101(gene name)|psi-mi:TEX101(display_short)|uniprotkb:Cell surface receptor NYD-SP8(gene name synonym)|uniprotkb:SGRG(gene name synonym)|uniprotkb:Scleroderma-associated autoantigen(gene name synonym)|uniprotkb:Spermatogenesis-related gene protein(gene name synonym)|uniprotkb:UNQ867/PRO1884(orf name) psi-mi:praf2_human(display_long)|uniprotkb:PRAF2(gene name)|psi-mi:PRAF2(display_short)|uniprotkb:JM4(orf name) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Schiza et al. (2018) imex:IM-28077|pubmed:30097533 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-25505061|imex:IM-28077-3 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000131126(gene)|ensembl:ENST00000598265(transcript)|go:"GO:0001669"(acrosomal vesicle)|go:"GO:0002080"(acrosomal membrane)|go:"GO:0005576"(extracellular region)|go:"GO:0005886"(plasma membrane)|go:"GO:0007339"(binding of sperm to zona pellucida)|go:"GO:0009566"(fertilization)|go:"GO:0030317"(flagellated sperm motility)|go:"GO:0044853"(plasma membrane raft)|go:"GO:0046658"(anchored component of plasma membrane)|go:"GO:1901317"(regulation of flagellated sperm motility)|interpro:IPR016054(Ly-6 antigen / uPA receptor -like)|rcsb pdb:7BPR|reactome:R-HSA-163125|refseq:NP_001123483.1|refseq:NP_113639.4 ensembl:ENSG00000243279(gene)|ensembl:ENST00000553851(transcript)|go:"GO:0010008"(endosome membrane)|go:"GO:0015031"(protein transport)|go:"GO:0015813"(L-glutamate transmembrane transport)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|interpro:IPR004895(Prenylated rab acceptor PRA1)|mint:O60831|refseq:NP_009144.1 - - - figure legend:Fig.2A,Supp Table S5|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-testis)|taxid:9606(Homo sapiens) - 2020/03/24 2021/11/30 rogid:ZE4tXTFi7lUCcIbCL4KHzY3a6xM9606 rogid:ZCku1zr9TwPArrSO0aaKZlDsEyU9606 rigid:/AFat0DrynAJ5ofEnoPSTThlxCE false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9BY14 uniprotkb:Q3LXA3 intact:EBI-12549378|ensembl:ENSP00000472769|uniprotkb:Q7L5R2|uniprotkb:Q9BPY7 intact:EBI-4291069|uniprotkb:Q53EQ9|uniprotkb:Q9BVA7|uniprotkb:Q9H895|uniprotkb:Q2L9C1|ensembl:ENSP00000378360 psi-mi:tx101_human(display_long)|uniprotkb:TEX101(gene name)|psi-mi:TEX101(display_short)|uniprotkb:Cell surface receptor NYD-SP8(gene name synonym)|uniprotkb:SGRG(gene name synonym)|uniprotkb:Scleroderma-associated autoantigen(gene name synonym)|uniprotkb:Spermatogenesis-related gene protein(gene name synonym)|uniprotkb:UNQ867/PRO1884(orf name) psi-mi:tkfc_human(display_long)|uniprotkb:TKFC(gene name)|psi-mi:TKFC(display_short)|uniprotkb:"Bifunctional ATP-dependent dihydroxyacetone kinase/FAD-AMP lyase (cyclizing)"(gene name synonym)|uniprotkb:DAK(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Schiza et al. (2018) imex:IM-28077|pubmed:30097533 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-25505061|imex:IM-28077-3 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000131126(gene)|ensembl:ENST00000598265(transcript)|go:"GO:0001669"(acrosomal vesicle)|go:"GO:0002080"(acrosomal membrane)|go:"GO:0005576"(extracellular region)|go:"GO:0005886"(plasma membrane)|go:"GO:0007339"(binding of sperm to zona pellucida)|go:"GO:0009566"(fertilization)|go:"GO:0030317"(flagellated sperm motility)|go:"GO:0044853"(plasma membrane raft)|go:"GO:0046658"(anchored component of plasma membrane)|go:"GO:1901317"(regulation of flagellated sperm motility)|interpro:IPR016054(Ly-6 antigen / uPA receptor -like)|rcsb pdb:7BPR|reactome:R-HSA-163125|refseq:NP_001123483.1|refseq:NP_113639.4 refseq:NP_056348.2|ensembl:ENSG00000149476(gene)|ensembl:ENST00000394900(transcript)|go:"GO:0004371"(glycerone kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0019563"(glycerol catabolic process)|go:"GO:0034012"("FAD-AMP lyase (cyclizing) activity")|go:"GO:0039534"(negative regulation of MDA-5 signaling pathway)|go:"GO:0044262"(cellular carbohydrate metabolic process)|go:"GO:0045088"(regulation of innate immune response)|go:"GO:0046835"(carbohydrate phosphorylation)|go:"GO:0046872"(metal ion binding)|go:"GO:0050354"(triokinase activity)|go:"GO:0070062"(extracellular exosome)|interpro:IPR004006(Dak kinase)|interpro:IPR004007(Dak phosphatase)|interpro:IPR012734(Dihydroxyacetone kinase)|interpro:IPR036117|reactome:R-HSA-168928|reactome:R-HSA-70350|refseq:XP_016873010.1|refseq:XP_016873012.1|dip:DIP-60967N - - - figure legend:Fig.2A,Supp Table S5|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-testis)|taxid:9606(Homo sapiens) - 2020/03/24 2021/11/30 rogid:ZE4tXTFi7lUCcIbCL4KHzY3a6xM9606 rogid:E+AbxQPIV/ejY4usEhwEqci9yUA9606 rigid:/AFat0DrynAJ5ofEnoPSTThlxCE false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9BY14 uniprotkb:Q08722 intact:EBI-12549378|ensembl:ENSP00000472769|uniprotkb:Q7L5R2|uniprotkb:Q9BPY7 intact:EBI-1268321|uniprotkb:Q53Y71|uniprotkb:Q96A60|uniprotkb:A8K198|uniprotkb:D3DN59|ensembl:ENSP00000355361 psi-mi:tx101_human(display_long)|uniprotkb:TEX101(gene name)|psi-mi:TEX101(display_short)|uniprotkb:Cell surface receptor NYD-SP8(gene name synonym)|uniprotkb:SGRG(gene name synonym)|uniprotkb:Scleroderma-associated autoantigen(gene name synonym)|uniprotkb:Spermatogenesis-related gene protein(gene name synonym)|uniprotkb:UNQ867/PRO1884(orf name) psi-mi:cd47_human(display_long)|uniprotkb:CD47(gene name)|psi-mi:CD47(display_short)|uniprotkb:MER6(gene name synonym)|uniprotkb:Integrin-associated protein(gene name synonym)|uniprotkb:Antigenic surface determinant protein OA3(gene name synonym)|uniprotkb:Protein MER6(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Schiza et al. (2018) imex:IM-28077|pubmed:30097533 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-25505061|imex:IM-28077-3 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000131126(gene)|ensembl:ENST00000598265(transcript)|go:"GO:0001669"(acrosomal vesicle)|go:"GO:0002080"(acrosomal membrane)|go:"GO:0005576"(extracellular region)|go:"GO:0005886"(plasma membrane)|go:"GO:0007339"(binding of sperm to zona pellucida)|go:"GO:0009566"(fertilization)|go:"GO:0030317"(flagellated sperm motility)|go:"GO:0044853"(plasma membrane raft)|go:"GO:0046658"(anchored component of plasma membrane)|go:"GO:1901317"(regulation of flagellated sperm motility)|interpro:IPR016054(Ly-6 antigen / uPA receptor -like)|rcsb pdb:7BPR|reactome:R-HSA-163125|refseq:NP_001123483.1|refseq:NP_113639.4 refseq:NP_001768.1|refseq:NP_942088.1|dip:DIP-39948N|ensembl:ENSG00000196776(gene)|ensembl:ENST00000361309(transcript)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0009986"(cell surface)|go:"GO:0016477"(cell migration)|go:"GO:0022409"(positive regulation of cell-cell adhesion)|go:"GO:0032649"(regulation of interferon-gamma production)|go:"GO:0032653"(regulation of interleukin-10 production)|go:"GO:0032655"(regulation of interleukin-12 production)|go:"GO:0032675"(regulation of interleukin-6 production)|go:"GO:0032680"(regulation of tumor necrosis factor production)|go:"GO:0035579"(specific granule membrane)|go:"GO:0045428"(regulation of nitric oxide biosynthetic process)|go:"GO:0050729"(positive regulation of inflammatory response)|go:"GO:0050766"(positive regulation of phagocytosis)|go:"GO:0050870"(positive regulation of T cell activation)|go:"GO:0051496"(positive regulation of stress fiber assembly)|go:"GO:0070053"(thrombospondin receptor activity)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070821"(tertiary granule membrane)|go:"GO:0071346"(cellular response to interferon-gamma)|go:"GO:0071347"(cellular response to interleukin-1)|go:"GO:0071349"(cellular response to interleukin-12)|go:"GO:0086080"(protein binding involved in heterotypic cell-cell adhesion)|go:"GO:0098632"(cell-cell adhesion mediator activity)|go:"GO:1904669"(ATP export)|go:"GO:0007229"(integrin-mediated signaling pathway)|go:"GO:2000439"(positive regulation of monocyte extravasation)|interpro:IPR006704(CD47 integrin associated protein)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR013147(CD47 transmembrane)|interpro:IPR013270(CD47 immunoglobulin-like)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR036179|interpro:IPR037805|rcsb pdb:2JJS|rcsb pdb:2JJT|rcsb pdb:2VSC|rcsb pdb:4CMM|rcsb pdb:4KJY|rcsb pdb:5IWL|rcsb pdb:5TZ2|rcsb pdb:5TZT|rcsb pdb:5TZU|reactome:R-HSA-202733|reactome:R-HSA-216083|reactome:R-HSA-391160|reactome:R-HSA-6798695|go:"GO:1905450"(negative regulation of Fc-gamma receptor signaling pathway involved in phagocytosis) - - - figure legend:Fig.2A,Supp Table S5|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-testis)|taxid:9606(Homo sapiens) - 2020/03/24 2021/11/30 rogid:ZE4tXTFi7lUCcIbCL4KHzY3a6xM9606 rogid:2hhmwvfeDFe7KHXzsBOJkjo2pjk9606 rigid:/AFat0DrynAJ5ofEnoPSTThlxCE false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9BY14 uniprotkb:Q8TDX9 intact:EBI-12549378|ensembl:ENSP00000472769|uniprotkb:Q7L5R2|uniprotkb:Q9BPY7 intact:EBI-25505114|ensembl:ENSP00000289672|uniprotkb:Q6UWK1 psi-mi:tx101_human(display_long)|uniprotkb:TEX101(gene name)|psi-mi:TEX101(display_short)|uniprotkb:Cell surface receptor NYD-SP8(gene name synonym)|uniprotkb:SGRG(gene name synonym)|uniprotkb:Scleroderma-associated autoantigen(gene name synonym)|uniprotkb:Spermatogenesis-related gene protein(gene name synonym)|uniprotkb:UNQ867/PRO1884(orf name) psi-mi:pk1l1_human(display_long)|uniprotkb:PKD1L1(gene name)|psi-mi:PKD1L1(display_short)|uniprotkb:PC1-like 1 protein(gene name synonym)|uniprotkb:Polycystin-1L1(gene name synonym)|uniprotkb:UNQ5785/PRO19563(orf name) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Schiza et al. (2018) imex:IM-28077|pubmed:30097533 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-25505061|imex:IM-28077-3 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000131126(gene)|ensembl:ENST00000598265(transcript)|go:"GO:0001669"(acrosomal vesicle)|go:"GO:0002080"(acrosomal membrane)|go:"GO:0005576"(extracellular region)|go:"GO:0005886"(plasma membrane)|go:"GO:0007339"(binding of sperm to zona pellucida)|go:"GO:0009566"(fertilization)|go:"GO:0030317"(flagellated sperm motility)|go:"GO:0044853"(plasma membrane raft)|go:"GO:0046658"(anchored component of plasma membrane)|go:"GO:1901317"(regulation of flagellated sperm motility)|interpro:IPR016054(Ly-6 antigen / uPA receptor -like)|rcsb pdb:7BPR|reactome:R-HSA-163125|refseq:NP_001123483.1|refseq:NP_113639.4 ensembl:ENSG00000158683(gene)|ensembl:ENST00000289672(transcript)|go:"GO:0003127"(detection of nodal flow)|go:"GO:0005262"(calcium channel activity)|go:"GO:0005929"(cilium)|go:"GO:0016020"(membrane)|go:"GO:0034704"(calcium channel complex)|go:"GO:0050982"(detection of mechanical stimulus)|go:"GO:0060170"(ciliary membrane)|go:"GO:0070986"(left/right axis specification)|go:"GO:0097730"(non-motile cilium)|go:"GO:0098609"(cell-cell adhesion)|interpro:IPR000601(PKD)|interpro:IPR001024(Lipoxygenase, LH2)|interpro:IPR002859(PKD/REJ-like protein)|interpro:IPR013122(Polycystin cation channel, PKD1/PKD2)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR014010(Egg jelly receptor, REJ-like)|interpro:IPR022409|interpro:IPR035986|interpro:IPR036392|interpro:IPR042060|refseq:NP_612152.1 - - - figure legend:Fig.2A,Supp Table S5|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-testis)|taxid:9606(Homo sapiens) - 2020/03/24 2021/11/30 rogid:ZE4tXTFi7lUCcIbCL4KHzY3a6xM9606 rogid:Uj2ige854frksIulRIELcPDg4Jk9606 rigid:/AFat0DrynAJ5ofEnoPSTThlxCE false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9BY14 uniprotkb:Q9NUQ9 intact:EBI-12549378|ensembl:ENSP00000472769|uniprotkb:Q7L5R2|uniprotkb:Q9BPY7 intact:EBI-1055930|uniprotkb:Q96AZ5|uniprotkb:Q9NZE7|uniprotkb:Q9NW21|ensembl:ENSP00000384880|ensembl:ENSP00000428117|ensembl:ENSP00000429078|ensembl:ENSP00000429150|ensembl:ENSP00000429499|ensembl:ENSP00000429802|ensembl:ENSP00000430674 psi-mi:tx101_human(display_long)|uniprotkb:TEX101(gene name)|psi-mi:TEX101(display_short)|uniprotkb:Cell surface receptor NYD-SP8(gene name synonym)|uniprotkb:SGRG(gene name synonym)|uniprotkb:Scleroderma-associated autoantigen(gene name synonym)|uniprotkb:Spermatogenesis-related gene protein(gene name synonym)|uniprotkb:UNQ867/PRO1884(orf name) psi-mi:cyrib_human(display_long)|uniprotkb:CYRIB(gene name)|psi-mi:CYRIB(display_short)|uniprotkb:CYRI(gene name synonym)|uniprotkb:FAM49B(gene name synonym)|uniprotkb:L1(gene name synonym)|uniprotkb:BM-009(orf name) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Schiza et al. (2018) imex:IM-28077|pubmed:30097533 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-25505061|imex:IM-28077-3 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000131126(gene)|ensembl:ENST00000598265(transcript)|go:"GO:0001669"(acrosomal vesicle)|go:"GO:0002080"(acrosomal membrane)|go:"GO:0005576"(extracellular region)|go:"GO:0005886"(plasma membrane)|go:"GO:0007339"(binding of sperm to zona pellucida)|go:"GO:0009566"(fertilization)|go:"GO:0030317"(flagellated sperm motility)|go:"GO:0044853"(plasma membrane raft)|go:"GO:0046658"(anchored component of plasma membrane)|go:"GO:1901317"(regulation of flagellated sperm motility)|interpro:IPR016054(Ly-6 antigen / uPA receptor -like)|rcsb pdb:7BPR|reactome:R-HSA-163125|refseq:NP_001123483.1|refseq:NP_113639.4 refseq:XP_011515410.1|refseq:XP_011515411.1|refseq:XP_011515412.1|refseq:XP_011515413.1|refseq:XP_011515415.1|refseq:XP_011515414.1|refseq:NP_001243692.1|refseq:XP_011515416.1|refseq:XP_011515417.1|refseq:XP_011515423.1|refseq:XP_011515424.1|refseq:XP_011515425.1|refseq:XP_011515426.1|refseq:XP_011515427.1|refseq:NP_057707.3|ensembl:ENSG00000153310(gene)|ensembl:ENST00000401979(transcript)|ensembl:ENST00000517654(transcript)|ensembl:ENST00000519110(transcript)|ensembl:ENST00000519540(transcript)|ensembl:ENST00000519824(transcript)|ensembl:ENST00000522746(transcript)|ensembl:ENST00000523509(transcript)|go:"GO:0001916"(positive regulation of T cell mediated cytotoxicity)|go:"GO:0005576"(extracellular region)|go:"GO:0005739"(mitochondrion)|go:"GO:0005929"(cilium)|go:"GO:0016020"(membrane)|go:"GO:0023030"(MHC class Ib protein binding, via antigen binding groove)|go:"GO:0030334"(regulation of cell migration)|go:"GO:0030837"(negative regulation of actin filament polymerization)|go:"GO:0031093"(platelet alpha granule lumen)|go:"GO:0031267"(small GTPase binding)|go:"GO:0032729"(positive regulation of interferon-gamma production)|go:"GO:0050870"(positive regulation of T cell activation)|go:"GO:0050920"(regulation of chemotaxis)|go:"GO:0051058"(negative regulation of small GTPase mediated signal transduction)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071219"(cellular response to molecule of bacterial origin)|go:"GO:0090140"(regulation of mitochondrial fission)|go:"GO:2000114"(regulation of establishment of cell polarity)|go:"GO:2000568"(positive regulation of memory T cell activation)|interpro:IPR009828(Protein of unknown function DUF1394)|interpro:IPR039789|rcsb pdb:7AJK|reactome:R-HSA-114608|refseq:NP_001317541.1|refseq:XP_016869028.1|refseq:XP_016869029.1|refseq:XP_016869030.1|refseq:XP_016869031.1|refseq:XP_016869032.1|refseq:XP_016869033.1|refseq:XP_016869034.1|refseq:XP_016869035.1|refseq:XP_016869036.1|refseq:XP_016869037.1|refseq:XP_016869038.1|refseq:XP_016869039.1|refseq:XP_016869040.1|refseq:XP_016869047.1|refseq:XP_016869048.1|refseq:XP_016869049.1|refseq:XP_016869050.1|refseq:XP_016869051.1 - - - figure legend:Fig.2A,Supp Table S5|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-testis)|taxid:9606(Homo sapiens) - 2020/03/24 2021/11/30 rogid:ZE4tXTFi7lUCcIbCL4KHzY3a6xM9606 rogid:x123Rh78yRGOGEgYIBIm/a+45ss9606 rigid:/AFat0DrynAJ5ofEnoPSTThlxCE false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9BY14 uniprotkb:P22102 intact:EBI-12549378|ensembl:ENSP00000472769|uniprotkb:Q7L5R2|uniprotkb:Q9BPY7 intact:EBI-356297|ensembl:ENSP00000371236|ensembl:ENSP00000371253|ensembl:ENSP00000371261|ensembl:ENSP00000459391|ensembl:ENSP00000459532|ensembl:ENSP00000461700|uniprotkb:D3DSF3|uniprotkb:D3DSF4|uniprotkb:O14659|uniprotkb:A8KA32|uniprotkb:A8K945|uniprotkb:Q52M77 psi-mi:tx101_human(display_long)|uniprotkb:TEX101(gene name)|psi-mi:TEX101(display_short)|uniprotkb:Cell surface receptor NYD-SP8(gene name synonym)|uniprotkb:SGRG(gene name synonym)|uniprotkb:Scleroderma-associated autoantigen(gene name synonym)|uniprotkb:Spermatogenesis-related gene protein(gene name synonym)|uniprotkb:UNQ867/PRO1884(orf name) psi-mi:pur2_human(display_long)|uniprotkb:GART(gene name)|psi-mi:GART(display_short)|uniprotkb:PRGS(gene name synonym)|uniprotkb:PGFT(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Schiza et al. (2018) imex:IM-28077|pubmed:30097533 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-25505061|imex:IM-28077-3 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000131126(gene)|ensembl:ENST00000598265(transcript)|go:"GO:0001669"(acrosomal vesicle)|go:"GO:0002080"(acrosomal membrane)|go:"GO:0005576"(extracellular region)|go:"GO:0005886"(plasma membrane)|go:"GO:0007339"(binding of sperm to zona pellucida)|go:"GO:0009566"(fertilization)|go:"GO:0030317"(flagellated sperm motility)|go:"GO:0044853"(plasma membrane raft)|go:"GO:0046658"(anchored component of plasma membrane)|go:"GO:1901317"(regulation of flagellated sperm motility)|interpro:IPR016054(Ly-6 antigen / uPA receptor -like)|rcsb pdb:7BPR|reactome:R-HSA-163125|refseq:NP_001123483.1|refseq:NP_113639.4 go:"GO:0006164"(purine nucleotide biosynthetic process)|go:"GO:0006189"('de novo' IMP biosynthetic process)|go:"GO:0006544"(glycine metabolic process)|go:"GO:0009168"(purine ribonucleoside monophosphate biosynthetic process)|go:"GO:0010033"(response to organic substance)|go:"GO:0010035"(response to inorganic substance)|go:"GO:0021549"(cerebellum development)|go:"GO:0021987"(cerebral cortex development)|go:"GO:0046084"(adenine biosynthetic process)|go:"GO:0046654"(tetrahydrofolate biosynthetic process)|go:"GO:0046872"(metal ion binding)|go:"GO:0070062"(extracellular exosome)|interpro:IPR000115(Phosphoribosylglycinamide synthetase)|interpro:IPR001555(Phosphoribosylglycinamide formyltransferase, active site)|interpro:IPR002376(Formyl transferase, N-terminal)|interpro:IPR004607(Phosphoribosylglycinamide formyltransferase)|interpro:IPR004733(Phosphoribosylformylglycinamidine cyclo-ligase)|interpro:IPR010918(AIR synthase related protein, C-terminal)|ensembl:ENST00000571089(transcript)|interpro:IPR011054(Rudiment single hybrid motif)|interpro:IPR011761(ATP-grasp fold)|ensembl:ENST00000573055(transcript)|ensembl:ENST00000575273(transcript)|go:"GO:0003360"(brainstem development)|go:"GO:0004637"(phosphoribosylamine-glycine ligase activity)|go:"GO:0004641"(phosphoribosylformylglycinamidine cyclo-ligase activity)|interpro:IPR013815(ATP-grasp fold, subdomain 1)|go:"GO:0004644"(phosphoribosylglycinamide formyltransferase activity)|interpro:IPR016185(PreATP-grasp-like fold)|go:"GO:0005524"(ATP binding)|go:"GO:0005829"(cytosol)|interpro:IPR016188(PurM, N-terminal-like)|ensembl:ENSG00000159131(gene)|ensembl:ENSG00000262473(gene)|ensembl:ENST00000381815(transcript)|ensembl:ENST00000381831(transcript)|ensembl:ENST00000381839(transcript)|interpro:IPR020560|interpro:IPR020561|interpro:IPR020562|interpro:IPR036477|interpro:IPR036676|interpro:IPR036921|interpro:IPR037123|mint:P22102|rcsb pdb:1MEJ|rcsb pdb:1MEN|rcsb pdb:1MEO|rcsb pdb:1NJS|rcsb pdb:1RBM|rcsb pdb:1RBQ|rcsb pdb:1RBY|rcsb pdb:1RBZ|rcsb pdb:1RC0|rcsb pdb:1RC1|rcsb pdb:1ZLX|rcsb pdb:1ZLY|rcsb pdb:2QK4|rcsb pdb:2V9Y|rcsb pdb:4EW1|rcsb pdb:4EW2|rcsb pdb:4EW3|rcsb pdb:4ZYT|interpro:IPR020559|rcsb pdb:4ZYU|rcsb pdb:4ZYV|rcsb pdb:4ZYW|rcsb pdb:4ZYX|rcsb pdb:4ZYY|rcsb pdb:4ZYZ|rcsb pdb:4ZZ0|rcsb pdb:4ZZ1|rcsb pdb:4ZZ2|rcsb pdb:5J9F|rcsb pdb:7JG0|rcsb pdb:4ZZ3|refseq:NP_000810.1|refseq:NP_001129477.1|refseq:NP_001129478.1|refseq:NP_780294.1|rcsb pdb:7JG4|reactome:R-HSA-73817|rcsb pdb:7JG3|refseq:XP_011527828.1|refseq:XP_006724052.1|refseq:XP_006724053.1|refseq:XP_005260998.1 - - - figure legend:Fig.2A,Supp Table S5|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-testis)|taxid:9606(Homo sapiens) - 2020/03/24 2021/11/30 rogid:ZE4tXTFi7lUCcIbCL4KHzY3a6xM9606 rogid:7Iy33CtBsB8LHZFDP5mZ3eRX8pU9606 rigid:/AFat0DrynAJ5ofEnoPSTThlxCE false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9BY14 uniprotkb:P84074 intact:EBI-12549378|ensembl:ENSP00000472769|uniprotkb:Q7L5R2|uniprotkb:Q9BPY7 intact:EBI-12197079|ensembl:ENSP00000362566|uniprotkb:B2R9T3|uniprotkb:D3DPQ7|uniprotkb:P32076|uniprotkb:P41211|uniprotkb:P70510 psi-mi:tx101_human(display_long)|uniprotkb:TEX101(gene name)|psi-mi:TEX101(display_short)|uniprotkb:Cell surface receptor NYD-SP8(gene name synonym)|uniprotkb:SGRG(gene name synonym)|uniprotkb:Scleroderma-associated autoantigen(gene name synonym)|uniprotkb:Spermatogenesis-related gene protein(gene name synonym)|uniprotkb:UNQ867/PRO1884(orf name) psi-mi:hpca_human(display_long)|uniprotkb:HPCA(gene name)|psi-mi:HPCA(display_short)|uniprotkb:BDR2(gene name synonym)|uniprotkb:Calcium-binding protein BDR-2(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Schiza et al. (2018) imex:IM-28077|pubmed:30097533 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-25505061|imex:IM-28077-3 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000131126(gene)|ensembl:ENST00000598265(transcript)|go:"GO:0001669"(acrosomal vesicle)|go:"GO:0002080"(acrosomal membrane)|go:"GO:0005576"(extracellular region)|go:"GO:0005886"(plasma membrane)|go:"GO:0007339"(binding of sperm to zona pellucida)|go:"GO:0009566"(fertilization)|go:"GO:0030317"(flagellated sperm motility)|go:"GO:0044853"(plasma membrane raft)|go:"GO:0046658"(anchored component of plasma membrane)|go:"GO:1901317"(regulation of flagellated sperm motility)|interpro:IPR016054(Ly-6 antigen / uPA receptor -like)|rcsb pdb:7BPR|reactome:R-HSA-163125|refseq:NP_001123483.1|refseq:NP_113639.4 ensembl:ENSG00000121905(gene)|ensembl:ENST00000373467(transcript)|go:"GO:0003779"(actin binding)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0007420"(brain development)|go:"GO:0019722"(calcium-mediated signaling)|go:"GO:0019898"(extrinsic component of membrane)|go:"GO:0019900"(kinase binding)|go:"GO:0030424"(axon)|go:"GO:0031283"(negative regulation of guanylate cyclase activity)|go:"GO:0031584"(activation of phospholipase D activity)|go:"GO:0032590"(dendrite membrane)|go:"GO:0032809"(neuronal cell body membrane)|go:"GO:0032839"(dendrite cytoplasm)|go:"GO:0042802"(identical protein binding)|go:"GO:0043204"(perikaryon)|go:"GO:0044327"(dendritic spine head)|go:"GO:0045762"(positive regulation of adenylate cyclase activity)|go:"GO:0048839"(inner ear development)|go:"GO:0060041"(retina development in camera-type eye)|go:"GO:0071257"(cellular response to electrical stimulus)|go:"GO:0071277"(cellular response to calcium ion)|go:"GO:0090314"(positive regulation of protein targeting to membrane)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099149"(regulation of postsynaptic neurotransmitter receptor internalization)|go:"GO:1901385"(regulation of voltage-gated calcium channel activity)|go:"GO:1901986"(response to ketamine)|go:"GO:1902065"(response to L-glutamate)|go:"GO:1904009"(cellular response to monosodium glutamate)|go:"GO:1904010"(response to Aroclor 1254)|interpro:IPR002048(Calcium-binding EF-hand)|interpro:IPR011992(EF-Hand type)|interpro:IPR018247|interpro:IPR028846|rcsb pdb:5G4P|rcsb pdb:5G58|rcsb pdb:5M6C|refseq:NP_002134.2|refseq:XP_005270849.1|refseq:XP_016856607.1 - - - figure legend:Fig.2A,Supp Table S5|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-testis)|taxid:9606(Homo sapiens) - 2020/03/24 2021/11/30 rogid:ZE4tXTFi7lUCcIbCL4KHzY3a6xM9606 rogid:uqRvTKlr8zMg7+UAfYCSqOljrFc9606 rigid:/AFat0DrynAJ5ofEnoPSTThlxCE false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9BY14 uniprotkb:Q13508 intact:EBI-12549378|ensembl:ENSP00000472769|uniprotkb:Q7L5R2|uniprotkb:Q9BPY7 intact:EBI-3904355|uniprotkb:Q96HL1|uniprotkb:Q8WVJ7|uniprotkb:Q6FHT7|uniprotkb:Q53XW3|uniprotkb:Q93069|ensembl:ENSP00000348064 psi-mi:tx101_human(display_long)|uniprotkb:TEX101(gene name)|psi-mi:TEX101(display_short)|uniprotkb:Cell surface receptor NYD-SP8(gene name synonym)|uniprotkb:SGRG(gene name synonym)|uniprotkb:Scleroderma-associated autoantigen(gene name synonym)|uniprotkb:Spermatogenesis-related gene protein(gene name synonym)|uniprotkb:UNQ867/PRO1884(orf name) psi-mi:nar3_human(display_long)|uniprotkb:ART3(gene name)|psi-mi:ART3(display_short)|uniprotkb:TMART(gene name synonym)|uniprotkb:"Mono(ADP-ribosyl)transferase 3"(gene name synonym)|uniprotkb:"NAD(P)(+)--arginine ADP-ribosyltransferase 3"(gene name synonym)|uniprotkb:ADP-ribosyltransferase C2 and C3 toxin-like 3(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Schiza et al. (2018) imex:IM-28077|pubmed:30097533 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-25505061|imex:IM-28077-3 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000131126(gene)|ensembl:ENST00000598265(transcript)|go:"GO:0001669"(acrosomal vesicle)|go:"GO:0002080"(acrosomal membrane)|go:"GO:0005576"(extracellular region)|go:"GO:0005886"(plasma membrane)|go:"GO:0007339"(binding of sperm to zona pellucida)|go:"GO:0009566"(fertilization)|go:"GO:0030317"(flagellated sperm motility)|go:"GO:0044853"(plasma membrane raft)|go:"GO:0046658"(anchored component of plasma membrane)|go:"GO:1901317"(regulation of flagellated sperm motility)|interpro:IPR016054(Ly-6 antigen / uPA receptor -like)|rcsb pdb:7BPR|reactome:R-HSA-163125|refseq:NP_001123483.1|refseq:NP_113639.4 refseq:NP_001123488.1|refseq:NP_001123489.1|refseq:NP_001170.2|ensembl:ENSG00000156219(gene)|ensembl:ENST00000355810(transcript)|go:"GO:0003950"(NAD+ ADP-ribosyltransferase activity)|go:"GO:0005576"(extracellular region)|go:"GO:0005886"(plasma membrane)|go:"GO:0006471"(protein ADP-ribosylation)|go:"GO:0031225"(anchored component of membrane)|go:"GO:0031226"(intrinsic component of plasma membrane)|go:"GO:0070062"(extracellular exosome)|go:"GO:0106274"(NAD+-protein-arginine ADP-ribosyltransferase activity)|go:"GO:0106275"(NADP+-protein-arginine ADP-ribosyltransferase activity)|interpro:IPR000768("NAD:arginine ADP-ribosyltransferase, ART")|reactome:R-HSA-163125|go:"GO:0018120"(peptidyl-arginine ADP-ribosylation) - - - figure legend:Fig.2A,Supp Table S5|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-testis)|taxid:9606(Homo sapiens) - 2020/03/24 2021/11/30 rogid:ZE4tXTFi7lUCcIbCL4KHzY3a6xM9606 rogid:JxQqlEa6lC6ZXSyTp7aaYCNxq189606 rigid:/AFat0DrynAJ5ofEnoPSTThlxCE false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9BY14 uniprotkb:Q15019 intact:EBI-12549378|ensembl:ENSP00000472769|uniprotkb:Q7L5R2|uniprotkb:Q9BPY7 intact:EBI-741220|intact:EBI-28986019|ensembl:ENSP00000353157|ensembl:ENSP00000375832|ensembl:ENSP00000375834|ensembl:ENSP00000385172|uniprotkb:Q14132|uniprotkb:Q8IUK9|uniprotkb:Q96CB0|uniprotkb:B4DGE8|uniprotkb:Q53QU3 psi-mi:tx101_human(display_long)|uniprotkb:TEX101(gene name)|psi-mi:TEX101(display_short)|uniprotkb:Cell surface receptor NYD-SP8(gene name synonym)|uniprotkb:SGRG(gene name synonym)|uniprotkb:Scleroderma-associated autoantigen(gene name synonym)|uniprotkb:Spermatogenesis-related gene protein(gene name synonym)|uniprotkb:UNQ867/PRO1884(orf name) psi-mi:sept2_human(display_long)|uniprotkb:SEPTIN2(gene name)|psi-mi:SEPTIN2(display_short)|uniprotkb:DIFF6(gene name synonym)|uniprotkb:KIAA0158(gene name synonym)|uniprotkb:NEDD5(gene name synonym)|uniprotkb:Neural precursor cell expressed developmentally down-regulated protein 5(gene name synonym)|uniprotkb:SEPT2(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Schiza et al. (2018) imex:IM-28077|pubmed:30097533 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-25505061|imex:IM-28077-3 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000131126(gene)|ensembl:ENST00000598265(transcript)|go:"GO:0001669"(acrosomal vesicle)|go:"GO:0002080"(acrosomal membrane)|go:"GO:0005576"(extracellular region)|go:"GO:0005886"(plasma membrane)|go:"GO:0007339"(binding of sperm to zona pellucida)|go:"GO:0009566"(fertilization)|go:"GO:0030317"(flagellated sperm motility)|go:"GO:0044853"(plasma membrane raft)|go:"GO:0046658"(anchored component of plasma membrane)|go:"GO:1901317"(regulation of flagellated sperm motility)|interpro:IPR016054(Ly-6 antigen / uPA receptor -like)|rcsb pdb:7BPR|reactome:R-HSA-163125|refseq:NP_001123483.1|refseq:NP_113639.4 refseq:NP_001269901.1|refseq:NP_001269902.1|ensembl:ENSG00000168385(gene)|ensembl:ENST00000360051(transcript)|ensembl:ENST00000391971(transcript)|ensembl:ENST00000391973(transcript)|ensembl:ENST00000402092(transcript)|go:"GO:0000145"(exocyst)|go:"GO:0000776"(kinetochore)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005819"(spindle)|go:"GO:0005886"(plasma membrane)|go:"GO:0005930"(axoneme)|go:"GO:0005940"(septin ring)|go:"GO:0007224"(smoothened signaling pathway)|go:"GO:0007283"(spermatogenesis)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0017157"(regulation of exocytosis)|go:"GO:0030496"(midbody)|go:"GO:0031105"(septin complex)|go:"GO:0031175"(neuron projection development)|go:"GO:0032153"(cell division site)|go:"GO:0032154"(cleavage furrow)|go:"GO:0032391"(photoreceptor connecting cilium)|go:"GO:0034613"(cellular protein localization)|go:"GO:0042802"(identical protein binding)|go:"GO:0045171"(intercellular bridge)|go:"GO:0045296"(cadherin binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0060170"(ciliary membrane)|go:"GO:0060271"(cilium assembly)|go:"GO:0061640"(cytoskeleton-dependent cytokinesis)|go:"GO:0070062"(extracellular exosome)|go:"GO:0097227"(sperm annulus)|go:"GO:0097730"(non-motile cilium)|interpro:IPR008113(Septin 2)|interpro:IPR016491(Septin)|interpro:IPR027417|interpro:IPR030379|mint:Q15019|rcsb pdb:2QA5|rcsb pdb:2QAG|rcsb pdb:2QNR|rcsb pdb:6UPA|rcsb pdb:6UPQ|rcsb pdb:6UPR|reactome:R-HSA-5620912|refseq:NP_001008491.1|refseq:NP_001008492.1|refseq:NP_004395.1|refseq:NP_006146.1|refseq:XP_016859694.1|refseq:XP_016859695.1|refseq:NP_001307958.1|refseq:NP_001307959.1|refseq:NP_001307960.1|refseq:NP_001307961.1|refseq:NP_001307962.1|refseq:NP_001307963.1|refseq:NP_001307964.1|ensembl:ENSP00000353157|ensembl:ENSP00000375832|ensembl:ENSP00000375834|ensembl:ENST00000401990|ensembl:ENSP00000385109|ensembl:ENSP00000385172|ensembl:ENST00000616972|ensembl:ENSP00000479861|dip:DIP-38220N - - crc64:12CCBBE30806F92F figure legend:Fig.2A,Supp Table S5|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-testis)|taxid:9606(Homo sapiens) - 2020/03/24 2021/11/30 rogid:ZE4tXTFi7lUCcIbCL4KHzY3a6xM9606 rogid:H0Us8GtPe2XuXlOYXC0DX79kB/49606 rigid:/AFat0DrynAJ5ofEnoPSTThlxCE false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9BY14 uniprotkb:Q15233 intact:EBI-12549378|ensembl:ENSP00000472769|uniprotkb:Q7L5R2|uniprotkb:Q9BPY7 intact:EBI-350527|ensembl:ENSP00000503233|uniprotkb:O00201|uniprotkb:P30807|uniprotkb:Q12786|uniprotkb:Q9BQC5|ensembl:ENSP00000276079|ensembl:ENSP00000362947|ensembl:ENSP00000406673|ensembl:ENSP00000410299|ensembl:ENSP00000415777|ensembl:ENSP00000503031|ensembl:ENSP00000504314|ensembl:ENSP00000504351|uniprotkb:D3DVV4|uniprotkb:B7Z4C2|uniprotkb:F5GYZ3 psi-mi:tx101_human(display_long)|uniprotkb:TEX101(gene name)|psi-mi:TEX101(display_short)|uniprotkb:Cell surface receptor NYD-SP8(gene name synonym)|uniprotkb:SGRG(gene name synonym)|uniprotkb:Scleroderma-associated autoantigen(gene name synonym)|uniprotkb:Spermatogenesis-related gene protein(gene name synonym)|uniprotkb:UNQ867/PRO1884(orf name) psi-mi:nono_human(display_long)|uniprotkb:NONO(gene name)|psi-mi:NONO(display_short)|uniprotkb:NRB54(gene name synonym)|uniprotkb:54 kDa nuclear RNA- and DNA-binding protein(gene name synonym)|uniprotkb:"p54(nrb)"(gene name synonym)|uniprotkb:55 kDa nuclear protein(gene name synonym)|uniprotkb:NMT55(gene name synonym)|uniprotkb:DNA-binding p52/p100 complex, 52 kDa subunit(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Schiza et al. (2018) imex:IM-28077|pubmed:30097533 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-25505061|imex:IM-28077-3 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000131126(gene)|ensembl:ENST00000598265(transcript)|go:"GO:0001669"(acrosomal vesicle)|go:"GO:0002080"(acrosomal membrane)|go:"GO:0005576"(extracellular region)|go:"GO:0005886"(plasma membrane)|go:"GO:0007339"(binding of sperm to zona pellucida)|go:"GO:0009566"(fertilization)|go:"GO:0030317"(flagellated sperm motility)|go:"GO:0044853"(plasma membrane raft)|go:"GO:0046658"(anchored component of plasma membrane)|go:"GO:1901317"(regulation of flagellated sperm motility)|interpro:IPR016054(Ly-6 antigen / uPA receptor -like)|rcsb pdb:7BPR|reactome:R-HSA-163125|refseq:NP_001123483.1|refseq:NP_113639.4 refseq:NP_001138880.1|refseq:NP_001138881.1|refseq:NP_001138882.1|refseq:NP_031389.3|ensembl:ENSG00000147140(gene)|ensembl:ENST00000276079(transcript)|ensembl:ENST00000373841(transcript)|ensembl:ENST00000420903(transcript)|ensembl:ENST00000450092(transcript)|ensembl:ENST00000454976(transcript)|ensembl:ENST00000677274(transcript)|ensembl:ENST00000677446(transcript)|ensembl:ENST00000677612(transcript)|ensembl:ENST00000678231(transcript)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0001650"(fibrillar center)|go:"GO:0002218"(activation of innate immune response)|go:"GO:0003676"(nucleic acid binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006281"(DNA repair)|go:"GO:0006310"(DNA recombination)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006397"(mRNA processing)|go:"GO:0007623"(circadian rhythm)|go:"GO:0008380"(RNA splicing)|go:"GO:0016020"(membrane)|go:"GO:0016363"(nuclear matrix)|go:"GO:0016607"(nuclear speck)|go:"GO:0042382"(paraspeckles)|go:"GO:0042752"(regulation of circadian rhythm)|go:"GO:0042802"(identical protein binding)|go:"GO:0045087"(innate immune response)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0090575"(RNA polymerase II transcription regulator complex)|go:"GO:1903377"(negative regulation of oxidative stress-induced neuron intrinsic apoptotic signaling pathway)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR012975(NOPS)|interpro:IPR034552|interpro:IPR035979|mint:Q15233|rcsb pdb:3SDE|rcsb pdb:5IFM|rcsb pdb:6WMZ|rcsb pdb:7LRQ|dip:DIP-29951N - - - figure legend:Fig.2A,Supp Table S5|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-testis)|taxid:9606(Homo sapiens) - 2020/03/24 2021/11/30 rogid:ZE4tXTFi7lUCcIbCL4KHzY3a6xM9606 rogid:5W3ooO4h0qh3GKO+WjDrLBhihHA9606 rigid:/AFat0DrynAJ5ofEnoPSTThlxCE false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9BY14 uniprotkb:Q13596 intact:EBI-12549378|ensembl:ENSP00000472769|uniprotkb:Q7L5R2|uniprotkb:Q9BPY7 intact:EBI-2822329|uniprotkb:O60750|uniprotkb:A8K6T7|uniprotkb:A6NM19|uniprotkb:O60751|uniprotkb:H0Y2M5|uniprotkb:Q6ZRJ8|ensembl:ENSP00000453785 psi-mi:tx101_human(display_long)|uniprotkb:TEX101(gene name)|psi-mi:TEX101(display_short)|uniprotkb:Cell surface receptor NYD-SP8(gene name synonym)|uniprotkb:SGRG(gene name synonym)|uniprotkb:Scleroderma-associated autoantigen(gene name synonym)|uniprotkb:Spermatogenesis-related gene protein(gene name synonym)|uniprotkb:UNQ867/PRO1884(orf name) psi-mi:snx1_human(display_long)|uniprotkb:SNX1(gene name)|psi-mi:SNX1(display_short) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Schiza et al. (2018) imex:IM-28077|pubmed:30097533 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-25505061|imex:IM-28077-3 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000131126(gene)|ensembl:ENST00000598265(transcript)|go:"GO:0001669"(acrosomal vesicle)|go:"GO:0002080"(acrosomal membrane)|go:"GO:0005576"(extracellular region)|go:"GO:0005886"(plasma membrane)|go:"GO:0007339"(binding of sperm to zona pellucida)|go:"GO:0009566"(fertilization)|go:"GO:0030317"(flagellated sperm motility)|go:"GO:0044853"(plasma membrane raft)|go:"GO:0046658"(anchored component of plasma membrane)|go:"GO:1901317"(regulation of flagellated sperm motility)|interpro:IPR016054(Ly-6 antigen / uPA receptor -like)|rcsb pdb:7BPR|reactome:R-HSA-163125|refseq:NP_001123483.1|refseq:NP_113639.4 refseq:NP_003090.2|refseq:NP_683758.1|refseq:NP_001229862.1|ensembl:ENSG00000028528(gene)|ensembl:ENST00000559844(transcript)|go:"GO:0005154"(epidermal growth factor receptor binding)|go:"GO:0005158"(insulin receptor binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005764"(lysosome)|go:"GO:0005768"(endosome)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0010008"(endosome membrane)|go:"GO:0016020"(membrane)|go:"GO:0030027"(lamellipodium)|go:"GO:0030904"(retromer complex)|go:"GO:0030905"(retromer, tubulation complex)|go:"GO:0031623"(receptor internalization)|go:"GO:0031901"(early endosome membrane)|go:"GO:0031982"(vesicle)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034498"(early endosome to Golgi transport)|go:"GO:0035091"(phosphatidylinositol binding)|go:"GO:0042147"(retrograde transport, endosome to Golgi)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0045296"(cadherin binding)|go:"GO:0045732"(positive regulation of protein catabolic process)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0072673"(lamellipodium morphogenesis)|go:"GO:1990459"(transferrin receptor binding)|go:"GO:1990460"(leptin receptor binding)|interpro:IPR001683(Phox-like)|interpro:IPR005329(Sorting nexin, N-terminal)|interpro:IPR015404(Vps5 C terminal like)|interpro:IPR027267|interpro:IPR028660|interpro:IPR034901|mint:Q13596|rcsb pdb:2I4K|rcsb pdb:4FZS|interpro:IPR036871|dip:DIP-398N - - - figure legend:Fig.2A,Supp Table S5|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-testis)|taxid:9606(Homo sapiens) - 2020/03/24 2021/11/30 rogid:ZE4tXTFi7lUCcIbCL4KHzY3a6xM9606 rogid:nFyxCtQ9gHndLbuCjBiwhyWE5do9606 rigid:/AFat0DrynAJ5ofEnoPSTThlxCE false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9BY14 uniprotkb:P14384 intact:EBI-12549378|ensembl:ENSP00000472769|uniprotkb:Q7L5R2|uniprotkb:Q9BPY7 intact:EBI-2561541|ensembl:ENSP00000339157|ensembl:ENSP00000447255|ensembl:ENSP00000448517|uniprotkb:B2R800|uniprotkb:Q9H2K9 psi-mi:tx101_human(display_long)|uniprotkb:TEX101(gene name)|psi-mi:TEX101(display_short)|uniprotkb:Cell surface receptor NYD-SP8(gene name synonym)|uniprotkb:SGRG(gene name synonym)|uniprotkb:Scleroderma-associated autoantigen(gene name synonym)|uniprotkb:Spermatogenesis-related gene protein(gene name synonym)|uniprotkb:UNQ867/PRO1884(orf name) psi-mi:cbpm_human(display_long)|uniprotkb:CPM(gene name)|psi-mi:CPM(display_short) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Schiza et al. (2018) imex:IM-28077|pubmed:30097533 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-25505061|imex:IM-28077-3 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000131126(gene)|ensembl:ENST00000598265(transcript)|go:"GO:0001669"(acrosomal vesicle)|go:"GO:0002080"(acrosomal membrane)|go:"GO:0005576"(extracellular region)|go:"GO:0005886"(plasma membrane)|go:"GO:0007339"(binding of sperm to zona pellucida)|go:"GO:0009566"(fertilization)|go:"GO:0030317"(flagellated sperm motility)|go:"GO:0044853"(plasma membrane raft)|go:"GO:0046658"(anchored component of plasma membrane)|go:"GO:1901317"(regulation of flagellated sperm motility)|interpro:IPR016054(Ly-6 antigen / uPA receptor -like)|rcsb pdb:7BPR|reactome:R-HSA-163125|refseq:NP_001123483.1|refseq:NP_113639.4 ensembl:ENSG00000135678(gene)|ensembl:ENST00000338356(transcript)|ensembl:ENST00000546373(transcript)|ensembl:ENST00000551568(transcript)|go:"GO:0004180"(carboxypeptidase activity)|refseq:NP_001005502.1|refseq:NP_001865.1|refseq:NP_938079.1|go:"GO:0004181"(metallocarboxypeptidase activity)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0005886"(plasma membrane)|go:"GO:0006518"(peptide metabolic process)|go:"GO:0008270"(zinc ion binding)|go:"GO:0009653"(anatomical structure morphogenesis)|go:"GO:0009986"(cell surface)|go:"GO:0016485"(protein processing)|go:"GO:0031225"(anchored component of membrane)|go:"GO:0070062"(extracellular exosome)|interpro:IPR000834(Peptidase M14, carboxypeptidase A)|interpro:IPR008969(Carboxypeptidase-like, regulatory region)|interpro:IPR033842|rcsb pdb:1UWY|reactome:R-HSA-163125 - - - figure legend:Fig.2A,Supp Table S5|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-testis)|taxid:9606(Homo sapiens) - 2020/03/24 2021/11/30 rogid:ZE4tXTFi7lUCcIbCL4KHzY3a6xM9606 rogid:nczGYHxDk+MrUSPPoJM1pyDJYFA9606 rigid:/AFat0DrynAJ5ofEnoPSTThlxCE false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9BY14 uniprotkb:P10619 intact:EBI-12549378|ensembl:ENSP00000472769|uniprotkb:Q7L5R2|uniprotkb:Q9BPY7 intact:EBI-989654|uniprotkb:Q9BW68|uniprotkb:Q561W6|uniprotkb:Q5JZH1|uniprotkb:Q96KJ2|uniprotkb:Q9BR08|ensembl:ENSP00000361537|ensembl:ENSP00000475524|ensembl:ENSP00000493613|ensembl:ENSP00000191018|uniprotkb:B2R798 psi-mi:tx101_human(display_long)|uniprotkb:TEX101(gene name)|psi-mi:TEX101(display_short)|uniprotkb:Cell surface receptor NYD-SP8(gene name synonym)|uniprotkb:SGRG(gene name synonym)|uniprotkb:Scleroderma-associated autoantigen(gene name synonym)|uniprotkb:Spermatogenesis-related gene protein(gene name synonym)|uniprotkb:UNQ867/PRO1884(orf name) psi-mi:ppgb_human(display_long)|uniprotkb:Cathepsin A(gene name synonym)|uniprotkb:Carboxypeptidase C(gene name synonym)|uniprotkb:Protective protein for beta-galactosidase(gene name synonym)|uniprotkb:CTSA(gene name)|psi-mi:CTSA(display_short)|uniprotkb:PPGB(gene name synonym)|uniprotkb:Carboxypeptidase L(gene name synonym)|uniprotkb:Protective protein cathepsin A(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Schiza et al. (2018) imex:IM-28077|pubmed:30097533 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-25505061|imex:IM-28077-3 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000131126(gene)|ensembl:ENST00000598265(transcript)|go:"GO:0001669"(acrosomal vesicle)|go:"GO:0002080"(acrosomal membrane)|go:"GO:0005576"(extracellular region)|go:"GO:0005886"(plasma membrane)|go:"GO:0007339"(binding of sperm to zona pellucida)|go:"GO:0009566"(fertilization)|go:"GO:0030317"(flagellated sperm motility)|go:"GO:0044853"(plasma membrane raft)|go:"GO:0046658"(anchored component of plasma membrane)|go:"GO:1901317"(regulation of flagellated sperm motility)|interpro:IPR016054(Ly-6 antigen / uPA receptor -like)|rcsb pdb:7BPR|reactome:R-HSA-163125|refseq:NP_001123483.1|refseq:NP_113639.4 ensembl:ENSG00000064601(gene)|interpro:IPR001563(Peptidase S10, serine carboxypeptidase)|interpro:IPR018202|interpro:IPR029058|interpro:IPR033124|rcsb pdb:1IVY|rcsb pdb:3BP4|rcsb pdb:3BP7|rcsb pdb:3BXN|rcsb pdb:4AZ0|rcsb pdb:4AZ3|rcsb pdb:4CI9|rcsb pdb:4CIA|rcsb pdb:4CIB|rcsb pdb:4MWS|rcsb pdb:4MWT|rcsb pdb:6WIA|reactome:R-HSA-1660662|reactome:R-HSA-2132295|reactome:R-HSA-4085001|reactome:R-HSA-4341670|reactome:R-HSA-6798695|ensembl:ENST00000191018(transcript)|ensembl:ENST00000372459(transcript)|ensembl:ENST00000607482(transcript)|ensembl:ENST00000646241(transcript)|go:"GO:0004180"(carboxypeptidase activity)|go:"GO:0004185"(serine-type carboxypeptidase activity)|go:"GO:0005576"(extracellular region)|go:"GO:0005764"(lysosome)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0006508"(proteolysis)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0008047"(enzyme activator activity)|go:"GO:0016020"(membrane)|go:"GO:0031647"(regulation of protein stability)|go:"GO:0035578"(azurophil granule lumen)|go:"GO:0043202"(lysosomal lumen)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0070062"(extracellular exosome)|go:"GO:1904714"(regulation of chaperone-mediated autophagy)|go:"GO:1904715"(negative regulation of chaperone-mediated autophagy)|refseq:NP_000299.2|refseq:NP_001161066.1|refseq:NP_001121167.1 - - - figure legend:Fig.2A,Supp Table S5|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-testis)|taxid:9606(Homo sapiens) - 2020/03/24 2021/11/30 rogid:ZE4tXTFi7lUCcIbCL4KHzY3a6xM9606 rogid:l/CZaKjZTuZu1ROoJJZVsxobYrQ9606 rigid:/AFat0DrynAJ5ofEnoPSTThlxCE false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9BY14 uniprotkb:O00483 intact:EBI-12549378|ensembl:ENSP00000472769|uniprotkb:Q7L5R2|uniprotkb:Q9BPY7 intact:EBI-1049381|uniprotkb:Q6FHN5|uniprotkb:A4D109|ensembl:ENSP00000339720 psi-mi:tx101_human(display_long)|uniprotkb:TEX101(gene name)|psi-mi:TEX101(display_short)|uniprotkb:Cell surface receptor NYD-SP8(gene name synonym)|uniprotkb:SGRG(gene name synonym)|uniprotkb:Scleroderma-associated autoantigen(gene name synonym)|uniprotkb:Spermatogenesis-related gene protein(gene name synonym)|uniprotkb:UNQ867/PRO1884(orf name) psi-mi:ndua4_human(display_long)|uniprotkb:NADH-ubiquinone oxidoreductase MLRQ subunit(gene name synonym)|uniprotkb:Complex I-MLRQ(gene name synonym)|uniprotkb:NDUFA4(gene name)|psi-mi:NDUFA4(display_short) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Schiza et al. (2018) imex:IM-28077|pubmed:30097533 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-25505061|imex:IM-28077-3 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000131126(gene)|ensembl:ENST00000598265(transcript)|go:"GO:0001669"(acrosomal vesicle)|go:"GO:0002080"(acrosomal membrane)|go:"GO:0005576"(extracellular region)|go:"GO:0005886"(plasma membrane)|go:"GO:0007339"(binding of sperm to zona pellucida)|go:"GO:0009566"(fertilization)|go:"GO:0030317"(flagellated sperm motility)|go:"GO:0044853"(plasma membrane raft)|go:"GO:0046658"(anchored component of plasma membrane)|go:"GO:1901317"(regulation of flagellated sperm motility)|interpro:IPR016054(Ly-6 antigen / uPA receptor -like)|rcsb pdb:7BPR|reactome:R-HSA-163125|refseq:NP_001123483.1|refseq:NP_113639.4 refseq:NP_002480.1|ensembl:ENSG00000189043(gene)|ensembl:ENST00000339600(transcript)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005747"(mitochondrial respiratory chain complex I)|go:"GO:0005751"(mitochondrial respiratory chain complex IV)|go:"GO:0006120"(mitochondrial electron transport, NADH to ubiquinone)|go:"GO:0008137"("NADH dehydrogenase (ubiquinone) activity")|go:"GO:0044877"(protein-containing complex binding)|go:"GO:1902600"(proton transmembrane transport)|go:"GO:1904960"(positive regulation of cytochrome-c oxidase activity)|interpro:IPR010530(B12D)|mint:O00483|rcsb pdb:5Z62|reactome:R-HSA-5628897|reactome:R-HSA-611105|reactome:R-HSA-9707564 - - - figure legend:Fig.2A,Supp Table S5|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-testis)|taxid:9606(Homo sapiens) - 2020/03/24 2021/11/30 rogid:ZE4tXTFi7lUCcIbCL4KHzY3a6xM9606 rogid:TnrYlkH8abl42/yGsvfc8Bh6Mu09606 rigid:/AFat0DrynAJ5ofEnoPSTThlxCE false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9BY14 uniprotkb:P62195 intact:EBI-12549378|ensembl:ENSP00000472769|uniprotkb:Q7L5R2|uniprotkb:Q9BPY7 intact:EBI-357745|uniprotkb:O35051|uniprotkb:O43208|uniprotkb:P52915|uniprotkb:P47210|uniprotkb:P52916|uniprotkb:A8K763|uniprotkb:A8K3Z3|ensembl:ENSP00000310572 psi-mi:tx101_human(display_long)|uniprotkb:TEX101(gene name)|psi-mi:TEX101(display_short)|uniprotkb:Cell surface receptor NYD-SP8(gene name synonym)|uniprotkb:SGRG(gene name synonym)|uniprotkb:Scleroderma-associated autoantigen(gene name synonym)|uniprotkb:Spermatogenesis-related gene protein(gene name synonym)|uniprotkb:UNQ867/PRO1884(orf name) psi-mi:prs8_human(display_long)|uniprotkb:PSMC5(gene name)|psi-mi:PSMC5(display_short)|uniprotkb:SUG1(gene name synonym)|uniprotkb:Proteasome 26S subunit ATPase 5(gene name synonym)|uniprotkb:Proteasome subunit p45(gene name synonym)|uniprotkb:p45/SUG(gene name synonym)|uniprotkb:Thyroid hormone receptor-interacting protein 1(gene name synonym)|uniprotkb:26S proteasome AAA-ATPase subunit RPT6(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Schiza et al. (2018) imex:IM-28077|pubmed:30097533 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-25505061|imex:IM-28077-3 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000131126(gene)|ensembl:ENST00000598265(transcript)|go:"GO:0001669"(acrosomal vesicle)|go:"GO:0002080"(acrosomal membrane)|go:"GO:0005576"(extracellular region)|go:"GO:0005886"(plasma membrane)|go:"GO:0007339"(binding of sperm to zona pellucida)|go:"GO:0009566"(fertilization)|go:"GO:0030317"(flagellated sperm motility)|go:"GO:0044853"(plasma membrane raft)|go:"GO:0046658"(anchored component of plasma membrane)|go:"GO:1901317"(regulation of flagellated sperm motility)|interpro:IPR016054(Ly-6 antigen / uPA receptor -like)|rcsb pdb:7BPR|reactome:R-HSA-163125|refseq:NP_001123483.1|refseq:NP_113639.4 refseq:NP_001186092.1|refseq:NP_002796.4|reactome:R-HSA-195253|ensembl:ENSG00000087191(gene)|ensembl:ENST00000310144(transcript)|go:"GO:0000502"(proteasome complex)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0008134"(transcription factor binding)|go:"GO:0008540"(proteasome regulatory particle, base subcomplex)|go:"GO:0016020"(membrane)|go:"GO:0016234"(inclusion body)|go:"GO:0017025"(TBP-class protein binding)|go:"GO:0022624"(proteasome accessory complex)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0031531"(thyrotropin-releasing hormone receptor binding)|go:"GO:0031595"(nuclear proteasome complex)|go:"GO:0031597"(cytosolic proteasome complex)|go:"GO:0036402"(proteasome-activating activity)|go:"GO:0043069"(negative regulation of programmed cell death)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045899"(positive regulation of RNA polymerase II transcription preinitiation complex assembly)|go:"GO:0050804"(modulation of chemical synaptic transmission)|go:"GO:0070062"(extracellular exosome)|go:"GO:0072562"(blood microparticle)|go:"GO:0090261"(positive regulation of inclusion body assembly)|go:"GO:0098794"(postsynapse)|go:"GO:0140296"(general transcription initiation factor binding)|go:"GO:0140297"(DNA-binding transcription factor binding)|go:"GO:1901800"(positive regulation of proteasomal protein catabolic process)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR003959(AAA ATPase, core)|interpro:IPR003960(AAA ATPase, conserved site)|interpro:IPR005937(26S proteasome subunit P45)|interpro:IPR027417|interpro:IPR032501|interpro:IPR041569|mint:P62195|rcsb pdb:2KRK|rcsb pdb:3KW6|rcsb pdb:5GJQ|rcsb pdb:5GJR|rcsb pdb:5L4G|rcsb pdb:5LN3|rcsb pdb:5M32|rcsb pdb:5T0C|rcsb pdb:5T0G|rcsb pdb:5T0H|rcsb pdb:5T0I|rcsb pdb:5T0J|rcsb pdb:5VFP|rcsb pdb:5VFQ|rcsb pdb:5VFR|rcsb pdb:5VFS|rcsb pdb:5VFT|rcsb pdb:5VFU|rcsb pdb:5VGZ|rcsb pdb:5VHF|rcsb pdb:5VHH|rcsb pdb:5VHI|rcsb pdb:5VHJ|rcsb pdb:5VHM|rcsb pdb:5VHN|rcsb pdb:5VHO|rcsb pdb:5VHP|rcsb pdb:5VHQ|rcsb pdb:5VHR|rcsb pdb:5VHS|rcsb pdb:6MSB|rcsb pdb:6MSD|rcsb pdb:6MSG|rcsb pdb:6MSH|rcsb pdb:6MSJ|rcsb pdb:6MSK|rcsb pdb:6WJD|rcsb pdb:6WJN|reactome:R-HSA-1169091|reactome:R-HSA-1234176|reactome:R-HSA-1236974|reactome:R-HSA-1236978|reactome:R-HSA-174084|reactome:R-HSA-174113|reactome:R-HSA-174154|reactome:R-HSA-174178|reactome:R-HSA-174184|reactome:R-HSA-180534|reactome:R-HSA-180585|reactome:R-HSA-187577|reactome:R-HSA-202424|reactome:R-HSA-211733|reactome:R-HSA-2467813|reactome:R-HSA-2871837|reactome:R-HSA-349425|reactome:R-HSA-350562|reactome:R-HSA-382556|reactome:R-HSA-450408|reactome:R-HSA-4608870|reactome:R-HSA-4641257|reactome:R-HSA-4641258|reactome:R-HSA-5358346|reactome:R-HSA-5362768|reactome:R-HSA-5607761|reactome:R-HSA-5607764|reactome:R-HSA-5610780|reactome:R-HSA-5610783|reactome:R-HSA-5610785|reactome:R-HSA-5632684|reactome:R-HSA-5658442|reactome:R-HSA-5668541|reactome:R-HSA-5676590|reactome:R-HSA-5678895|reactome:R-HSA-5687128|reactome:R-HSA-5689603|reactome:R-HSA-5689880|reactome:R-HSA-68827|reactome:R-HSA-68949|reactome:R-HSA-69017|reactome:R-HSA-69481|reactome:R-HSA-69601|reactome:R-HSA-75815|reactome:R-HSA-8852276|reactome:R-HSA-8854050|reactome:R-HSA-8932339|reactome:R-HSA-8939236|reactome:R-HSA-8939902|reactome:R-HSA-8941858|reactome:R-HSA-8948751|reactome:R-HSA-8951664|reactome:R-HSA-9010553|reactome:R-HSA-9020702|reactome:R-HSA-9604323|reactome:R-HSA-983168|dip:DIP-36645N - - crc64:29C6410C4A85A7F7 figure legend:Fig.2A,Supp Table S5|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-testis)|taxid:9606(Homo sapiens) - 2020/03/24 2021/11/30 rogid:ZE4tXTFi7lUCcIbCL4KHzY3a6xM9606 rogid:zgUTOX/O4m86U/Nf+pnT7u0m0gY9606 rigid:/AFat0DrynAJ5ofEnoPSTThlxCE false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9BY14 uniprotkb:Q3ZCM7 intact:EBI-12549378|ensembl:ENSP00000472769|uniprotkb:Q7L5R2|uniprotkb:Q9BPY7 intact:EBI-302558|ensembl:ENSP00000456206|intact:EBI-1390656|uniprotkb:Q5SQX9|uniprotkb:Q8WZ78 psi-mi:tx101_human(display_long)|uniprotkb:TEX101(gene name)|psi-mi:TEX101(display_short)|uniprotkb:Cell surface receptor NYD-SP8(gene name synonym)|uniprotkb:SGRG(gene name synonym)|uniprotkb:Scleroderma-associated autoantigen(gene name synonym)|uniprotkb:Spermatogenesis-related gene protein(gene name synonym)|uniprotkb:UNQ867/PRO1884(orf name) psi-mi:tbb8_human(display_long)|uniprotkb:TUBB8(gene name)|psi-mi:TUBB8(display_short)|uniprotkb:Tubulin beta 8 class VIII(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Schiza et al. (2018) imex:IM-28077|pubmed:30097533 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-25505061|imex:IM-28077-3 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000131126(gene)|ensembl:ENST00000598265(transcript)|go:"GO:0001669"(acrosomal vesicle)|go:"GO:0002080"(acrosomal membrane)|go:"GO:0005576"(extracellular region)|go:"GO:0005886"(plasma membrane)|go:"GO:0007339"(binding of sperm to zona pellucida)|go:"GO:0009566"(fertilization)|go:"GO:0030317"(flagellated sperm motility)|go:"GO:0044853"(plasma membrane raft)|go:"GO:0046658"(anchored component of plasma membrane)|go:"GO:1901317"(regulation of flagellated sperm motility)|interpro:IPR016054(Ly-6 antigen / uPA receptor -like)|rcsb pdb:7BPR|reactome:R-HSA-163125|refseq:NP_001123483.1|refseq:NP_113639.4 reactome:R-HSA-9646399|reactome:R-HSA-9648025|reactome:R-HSA-9668328|reactome:R-HSA-983189|reactome:R-HSA-9619483|ensembl:ENSG00000261456(gene)|ensembl:ENST00000568584(transcript)|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0001556"(oocyte maturation)|go:"GO:0005200"(structural constituent of cytoskeleton)|go:"GO:0005525"(GTP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005874"(microtubule)|go:"GO:0007056"(spindle assembly involved in female meiosis)|go:"GO:0070062"(extracellular exosome)|go:"GO:0072687"(meiotic spindle)|interpro:IPR000217(Tubulin)|interpro:IPR002453(Beta tubulin)|interpro:IPR003008(Tubulin/FtsZ, GTPase)|interpro:IPR008280(Tubulin/FtsZ, C-terminal)|interpro:IPR013838(Beta tubulin, autoregulation binding site)|interpro:IPR017975|interpro:IPR018316|interpro:IPR023123|interpro:IPR036525|interpro:IPR037103|mint:Q3ZCM7|reactome:R-HSA-1445148|reactome:R-HSA-190840|reactome:R-HSA-190861|reactome:R-HSA-2132295|reactome:R-HSA-2467813|reactome:R-HSA-2500257|reactome:R-HSA-3371497|reactome:R-HSA-380320|reactome:R-HSA-437239|reactome:R-HSA-5617833|reactome:R-HSA-5626467|reactome:R-HSA-5663220|reactome:R-HSA-6807878|reactome:R-HSA-6811434|reactome:R-HSA-6811436|reactome:R-HSA-68877|reactome:R-HSA-8852276|reactome:R-HSA-8955332|reactome:R-HSA-9609690|reactome:R-HSA-9609736|refseq:NP_817124.1 - - - figure legend:Fig.2A,Supp Table S5|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-testis)|taxid:9606(Homo sapiens) - 2020/03/24 2021/11/30 rogid:ZE4tXTFi7lUCcIbCL4KHzY3a6xM9606 rogid:bTJnhl0qEm2ACoHQ7IOcn5Rx7xM9606 rigid:/AFat0DrynAJ5ofEnoPSTThlxCE false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9BY14 uniprotkb:P04843 intact:EBI-12549378|ensembl:ENSP00000472769|uniprotkb:Q7L5R2|uniprotkb:Q9BPY7 intact:EBI-355963|ensembl:ENSP00000296255|uniprotkb:D3DNB6|uniprotkb:Q68DT1|uniprotkb:B2R5Z0 psi-mi:tx101_human(display_long)|uniprotkb:TEX101(gene name)|psi-mi:TEX101(display_short)|uniprotkb:Cell surface receptor NYD-SP8(gene name synonym)|uniprotkb:SGRG(gene name synonym)|uniprotkb:Scleroderma-associated autoantigen(gene name synonym)|uniprotkb:Spermatogenesis-related gene protein(gene name synonym)|uniprotkb:UNQ867/PRO1884(orf name) psi-mi:rpn1_human(display_long)|uniprotkb:RPN1(gene name)|psi-mi:RPN1(display_short)|uniprotkb:Dolichyl-diphosphooligosaccharide--protein glycosyltransferase 67 kDa subunit(gene name synonym)|uniprotkb:Ribophorin-1(gene name synonym)|uniprotkb:Ribophorin I(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Schiza et al. (2018) imex:IM-28077|pubmed:30097533 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-25505061|imex:IM-28077-3 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000131126(gene)|ensembl:ENST00000598265(transcript)|go:"GO:0001669"(acrosomal vesicle)|go:"GO:0002080"(acrosomal membrane)|go:"GO:0005576"(extracellular region)|go:"GO:0005886"(plasma membrane)|go:"GO:0007339"(binding of sperm to zona pellucida)|go:"GO:0009566"(fertilization)|go:"GO:0030317"(flagellated sperm motility)|go:"GO:0044853"(plasma membrane raft)|go:"GO:0046658"(anchored component of plasma membrane)|go:"GO:1901317"(regulation of flagellated sperm motility)|interpro:IPR016054(Ly-6 antigen / uPA receptor -like)|rcsb pdb:7BPR|reactome:R-HSA-163125|refseq:NP_001123483.1|refseq:NP_113639.4 ensembl:ENSG00000163902(gene)|ensembl:ENST00000296255(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005791"(rough endoplasmic reticulum)|go:"GO:0005829"(cytosol)|go:"GO:0006487"(protein N-linked glycosylation)|go:"GO:0008250"(oligosaccharyltransferase complex)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0018279"(protein N-linked glycosylation via asparagine)|go:"GO:0042470"(melanosome)|interpro:IPR007676(Ribophorin I)|mint:P04843|rcsb pdb:6S7O|rcsb pdb:6S7T|reactome:R-HSA-1799339|reactome:R-HSA-446203|reactome:R-HSA-9694548|go:"GO:0006464"(cellular protein modification process)|refseq:NP_002941.1|dip:DIP-38152N - - - figure legend:Fig.2A,Supp Table S5|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-testis)|taxid:9606(Homo sapiens) - 2020/03/24 2021/11/30 rogid:ZE4tXTFi7lUCcIbCL4KHzY3a6xM9606 rogid:rvQThNB/dCCNR9+IDssZo1qgZUE9606 rigid:/AFat0DrynAJ5ofEnoPSTThlxCE false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9BY14 uniprotkb:Q9Y3I0 intact:EBI-12549378|ensembl:ENSP00000472769|uniprotkb:Q7L5R2|uniprotkb:Q9BPY7 intact:EBI-2107208|uniprotkb:Q6IAI0|uniprotkb:Q9BWL4|uniprotkb:Q9NTH1|uniprotkb:Q9P037|uniprotkb:Q9P0J3|uniprotkb:B2R6A8|intact:EBI-4399544|ensembl:ENSP00000216038 psi-mi:tx101_human(display_long)|uniprotkb:TEX101(gene name)|psi-mi:TEX101(display_short)|uniprotkb:Cell surface receptor NYD-SP8(gene name synonym)|uniprotkb:SGRG(gene name synonym)|uniprotkb:Scleroderma-associated autoantigen(gene name synonym)|uniprotkb:Spermatogenesis-related gene protein(gene name synonym)|uniprotkb:UNQ867/PRO1884(orf name) psi-mi:rtcb_human(display_long)|uniprotkb:3'-phosphate/5'-hydroxy nucleic acid ligase(gene name synonym)|uniprotkb:C22orf28(gene name synonym)|uniprotkb:HSPC117(orf name)|uniprotkb:RTCB(gene name)|psi-mi:RTCB(display_short) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Schiza et al. (2018) imex:IM-28077|pubmed:30097533 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-25505061|imex:IM-28077-3 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000131126(gene)|ensembl:ENST00000598265(transcript)|go:"GO:0001669"(acrosomal vesicle)|go:"GO:0002080"(acrosomal membrane)|go:"GO:0005576"(extracellular region)|go:"GO:0005886"(plasma membrane)|go:"GO:0007339"(binding of sperm to zona pellucida)|go:"GO:0009566"(fertilization)|go:"GO:0030317"(flagellated sperm motility)|go:"GO:0044853"(plasma membrane raft)|go:"GO:0046658"(anchored component of plasma membrane)|go:"GO:1901317"(regulation of flagellated sperm motility)|interpro:IPR016054(Ly-6 antigen / uPA receptor -like)|rcsb pdb:7BPR|reactome:R-HSA-163125|refseq:NP_001123483.1|refseq:NP_113639.4 refseq:NP_055121.1|dip:DIP-46750N|ensembl:ENSG00000100220(gene)|ensembl:ENST00000216038(transcript)|go:"GO:0000971"(tRNA exon ligation utilizing 2',3' cyclic phosphate of 5'-exon as source of linkage phosphate)|go:"GO:0003723"(RNA binding)|go:"GO:0003972"("RNA ligase (ATP) activity")|go:"GO:0005525"(GTP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006388"(tRNA splicing, via endonucleolytic cleavage and ligation)|go:"GO:0017166"(vinculin binding)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0046872"(metal ion binding)|go:"GO:0072669"(tRNA-splicing ligase complex)|interpro:IPR001233(Protein of unknown function UPF0027)|interpro:IPR027513|interpro:IPR036025|mint:Q9Y3I0|reactome:R-HSA-6784531 - - - figure legend:Fig.2A,Supp Table S5|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-testis)|taxid:9606(Homo sapiens) - 2020/03/24 2021/11/30 rogid:ZE4tXTFi7lUCcIbCL4KHzY3a6xM9606 rogid:URuCEq/DIn6DgR3jOb5fwnpDVXE9606 rigid:/AFat0DrynAJ5ofEnoPSTThlxCE false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9BY14 uniprotkb:O75915 intact:EBI-12549378|ensembl:ENSP00000472769|uniprotkb:Q7L5R2|uniprotkb:Q9BPY7 intact:EBI-2860752|uniprotkb:B2R6V5|uniprotkb:Q53ES3|uniprotkb:Q5KU08|ensembl:ENSP00000273258 psi-mi:tx101_human(display_long)|uniprotkb:TEX101(gene name)|psi-mi:TEX101(display_short)|uniprotkb:Cell surface receptor NYD-SP8(gene name synonym)|uniprotkb:SGRG(gene name synonym)|uniprotkb:Scleroderma-associated autoantigen(gene name synonym)|uniprotkb:Spermatogenesis-related gene protein(gene name synonym)|uniprotkb:UNQ867/PRO1884(orf name) psi-mi:praf3_human(display_long)|uniprotkb:ARL6IP5(gene name)|psi-mi:ARL6IP5(display_short)|uniprotkb:DERP11(gene name synonym)|uniprotkb:JWA(gene name synonym)|uniprotkb:PRA2(gene name synonym)|uniprotkb:PRAF3(gene name synonym)|uniprotkb:ADP-ribosylation factor-like protein 6-interacting protein 5(gene name synonym)|uniprotkb:Cytoskeleton-related vitamin A-responsive protein(gene name synonym)|uniprotkb:Dermal papilla-derived protein 11(gene name synonym)|uniprotkb:GTRAP3-18(gene name synonym)|uniprotkb:Glutamate transporter EAAC1-interacting protein(gene name synonym)|uniprotkb:JM5(gene name synonym)|uniprotkb:Prenylated Rab acceptor protein 2(gene name synonym)|uniprotkb:Protein JWa(gene name synonym)|uniprotkb:Putative MAPK-activating protein PM27(gene name synonym)|uniprotkb:HSPC127(orf name) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Schiza et al. (2018) imex:IM-28077|pubmed:30097533 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-25505061|imex:IM-28077-3 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000131126(gene)|ensembl:ENST00000598265(transcript)|go:"GO:0001669"(acrosomal vesicle)|go:"GO:0002080"(acrosomal membrane)|go:"GO:0005576"(extracellular region)|go:"GO:0005886"(plasma membrane)|go:"GO:0007339"(binding of sperm to zona pellucida)|go:"GO:0009566"(fertilization)|go:"GO:0030317"(flagellated sperm motility)|go:"GO:0044853"(plasma membrane raft)|go:"GO:0046658"(anchored component of plasma membrane)|go:"GO:1901317"(regulation of flagellated sperm motility)|interpro:IPR016054(Ly-6 antigen / uPA receptor -like)|rcsb pdb:7BPR|reactome:R-HSA-163125|refseq:NP_001123483.1|refseq:NP_113639.4 refseq:NP_006398.1|go:"GO:0043280"(positive regulation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0051051"(negative regulation of transport)|go:"GO:0071407"(cellular response to organic cyclic compound)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0098712"(L-glutamate import across plasma membrane)|interpro:IPR004895(Prenylated rab acceptor PRA1)|mint:O75915|reactome:R-HSA-210500|ensembl:ENSG00000144746(gene)|ensembl:ENST00000273258(transcript)|go:"GO:0002037"(negative regulation of L-glutamate import across plasma membrane)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005886"(plasma membrane)|go:"GO:0006749"(glutathione metabolic process)|go:"GO:0007611"(learning or memory)|go:"GO:0008631"(intrinsic apoptotic signaling pathway in response to oxidative stress)|go:"GO:0010917"(negative regulation of mitochondrial membrane potential)|go:"GO:0015031"(protein transport)|go:"GO:0015813"(L-glutamate transmembrane transport)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0032874"(positive regulation of stress-activated MAPK cascade)|go:"GO:0036475"(neuron death in response to oxidative stress)|go:"GO:0043065"(positive regulation of apoptotic process) - - - figure legend:Fig.2A,Supp Table S5|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-testis)|taxid:9606(Homo sapiens) - 2020/03/24 2021/11/30 rogid:ZE4tXTFi7lUCcIbCL4KHzY3a6xM9606 rogid:TG2yH1gqzVhFgxBtuZqsE1dLAvQ9606 rigid:/AFat0DrynAJ5ofEnoPSTThlxCE false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9BY14 uniprotkb:Q9BVK6 intact:EBI-12549378|ensembl:ENSP00000472769|uniprotkb:Q7L5R2|uniprotkb:Q9BPY7 intact:EBI-1056827|uniprotkb:Q8WZ61|uniprotkb:Q14437|ensembl:ENSP00000330945 psi-mi:tx101_human(display_long)|uniprotkb:TEX101(gene name)|psi-mi:TEX101(display_short)|uniprotkb:Cell surface receptor NYD-SP8(gene name synonym)|uniprotkb:SGRG(gene name synonym)|uniprotkb:Scleroderma-associated autoantigen(gene name synonym)|uniprotkb:Spermatogenesis-related gene protein(gene name synonym)|uniprotkb:UNQ867/PRO1884(orf name) psi-mi:tmed9_human(display_long)|uniprotkb:TMED9(gene name)|psi-mi:TMED9(display_short)|uniprotkb:GP25L2(gene name synonym)|uniprotkb:Glycoprotein 25L2(gene name synonym)|uniprotkb:p25(gene name synonym)|uniprotkb:p24 family protein alpha-2(gene name synonym)|uniprotkb:GMP25(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Schiza et al. (2018) imex:IM-28077|pubmed:30097533 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-25505061|imex:IM-28077-3 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000131126(gene)|ensembl:ENST00000598265(transcript)|go:"GO:0001669"(acrosomal vesicle)|go:"GO:0002080"(acrosomal membrane)|go:"GO:0005576"(extracellular region)|go:"GO:0005886"(plasma membrane)|go:"GO:0007339"(binding of sperm to zona pellucida)|go:"GO:0009566"(fertilization)|go:"GO:0030317"(flagellated sperm motility)|go:"GO:0044853"(plasma membrane raft)|go:"GO:0046658"(anchored component of plasma membrane)|go:"GO:1901317"(regulation of flagellated sperm motility)|interpro:IPR016054(Ly-6 antigen / uPA receptor -like)|rcsb pdb:7BPR|reactome:R-HSA-163125|refseq:NP_001123483.1|refseq:NP_113639.4 refseq:NP_059980.2|ensembl:ENSG00000184840(gene)|ensembl:ENST00000332598(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005793"(endoplasmic reticulum-Golgi intermediate compartment)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0007030"(Golgi organization)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0010638"(positive regulation of organelle organization)|go:"GO:0016021"(integral component of membrane)|go:"GO:0019905"(syntaxin binding)|go:"GO:0030133"(transport vesicle)|go:"GO:0030134"(COPII-coated ER to Golgi transport vesicle)|go:"GO:0030140"(trans-Golgi network transport vesicle)|go:"GO:0033116"(endoplasmic reticulum-Golgi intermediate compartment membrane)|go:"GO:0048205"(COPI coating of Golgi vesicle)|go:"GO:0070062"(extracellular exosome)|interpro:IPR009038(GOLD)|interpro:IPR015720(TMP21 related)|mint:Q9BVK6|reactome:R-HSA-6807878|reactome:R-HSA-6811434 - - - figure legend:Fig.2A,Supp Table S5|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-testis)|taxid:9606(Homo sapiens) - 2020/03/24 2021/11/30 rogid:ZE4tXTFi7lUCcIbCL4KHzY3a6xM9606 rogid:z5YDyY6mtnc4WGWU9G9sNgp+Ga09606 rigid:/AFat0DrynAJ5ofEnoPSTThlxCE false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9BY14 uniprotkb:Q96BM9 intact:EBI-12549378|ensembl:ENSP00000472769|uniprotkb:Q7L5R2|uniprotkb:Q9BPY7 intact:EBI-4401082|uniprotkb:B3KXD0|ensembl:ENSP00000272217 psi-mi:tx101_human(display_long)|uniprotkb:TEX101(gene name)|psi-mi:TEX101(display_short)|uniprotkb:Cell surface receptor NYD-SP8(gene name synonym)|uniprotkb:SGRG(gene name synonym)|uniprotkb:Scleroderma-associated autoantigen(gene name synonym)|uniprotkb:Spermatogenesis-related gene protein(gene name synonym)|uniprotkb:UNQ867/PRO1884(orf name) psi-mi:arl8a_human(display_long)|uniprotkb:ARL8A(gene name)|psi-mi:ARL8A(display_short)|uniprotkb:ARL10B(gene name synonym)|uniprotkb:GIE2(gene name synonym)|uniprotkb:ADP-ribosylation factor-like protein 10B(gene name synonym)|uniprotkb:Novel small G protein indispensable for equal chromosome segregation 2(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Schiza et al. (2018) imex:IM-28077|pubmed:30097533 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-25505061|imex:IM-28077-3 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000131126(gene)|ensembl:ENST00000598265(transcript)|go:"GO:0001669"(acrosomal vesicle)|go:"GO:0002080"(acrosomal membrane)|go:"GO:0005576"(extracellular region)|go:"GO:0005886"(plasma membrane)|go:"GO:0007339"(binding of sperm to zona pellucida)|go:"GO:0009566"(fertilization)|go:"GO:0030317"(flagellated sperm motility)|go:"GO:0044853"(plasma membrane raft)|go:"GO:0046658"(anchored component of plasma membrane)|go:"GO:1901317"(regulation of flagellated sperm motility)|interpro:IPR016054(Ly-6 antigen / uPA receptor -like)|rcsb pdb:7BPR|reactome:R-HSA-163125|refseq:NP_001123483.1|refseq:NP_113639.4 refseq:NP_620150.1|refseq:NP_001243058.1|ensembl:ENSG00000143862(gene)|ensembl:ENST00000272217(transcript)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005774"(vacuolar membrane)|go:"GO:0005886"(plasma membrane)|go:"GO:0007049"(cell cycle)|go:"GO:0007059"(chromosome segregation)|go:"GO:0008089"(anterograde axonal transport)|go:"GO:0015031"(protein transport)|go:"GO:0016020"(membrane)|go:"GO:0030496"(midbody)|go:"GO:0031902"(late endosome membrane)|go:"GO:0035577"(azurophil granule membrane)|go:"GO:0043014"(alpha-tubulin binding)|go:"GO:0045202"(synapse)|go:"GO:0048487"(beta-tubulin binding)|go:"GO:0051233"(spindle midzone)|go:"GO:0051301"(cell division)|go:"GO:0070062"(extracellular exosome)|go:"GO:0101003"(ficolin-1-rich granule membrane)|go:"GO:1904115"(axon cytoplasm)|interpro:IPR005225(Small GTP-binding protein)|interpro:IPR006689(ARF/SAR superfamily)|interpro:IPR027417|interpro:IPR044154|rcsb pdb:1ZD9|rcsb pdb:2H18|rcsb pdb:4ILE|reactome:R-HSA-6798695 - - - figure legend:Fig.2A,Supp Table S5|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-testis)|taxid:9606(Homo sapiens) - 2020/03/24 2021/11/30 rogid:ZE4tXTFi7lUCcIbCL4KHzY3a6xM9606 rogid:DZU9T4htQdahFZ8f2k2Fc4JqqZc9606 rigid:/AFat0DrynAJ5ofEnoPSTThlxCE false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9BY14 uniprotkb:P28066 intact:EBI-12549378|ensembl:ENSP00000472769|uniprotkb:Q7L5R2|uniprotkb:Q9BPY7 intact:EBI-355475|uniprotkb:B4E2V4|uniprotkb:Q6IBF7|uniprotkb:Q3T1C1|uniprotkb:B2R8F6|ensembl:ENSP00000271308 psi-mi:tx101_human(display_long)|uniprotkb:TEX101(gene name)|psi-mi:TEX101(display_short)|uniprotkb:Cell surface receptor NYD-SP8(gene name synonym)|uniprotkb:SGRG(gene name synonym)|uniprotkb:Scleroderma-associated autoantigen(gene name synonym)|uniprotkb:Spermatogenesis-related gene protein(gene name synonym)|uniprotkb:UNQ867/PRO1884(orf name) psi-mi:psa5_human(display_long)|uniprotkb:PSMA5(gene name)|psi-mi:PSMA5(display_short)|uniprotkb:Proteasome zeta chain(gene name synonym)|uniprotkb:Macropain zeta chain(gene name synonym)|uniprotkb:Multicatalytic endopeptidase complex zeta chain(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Schiza et al. (2018) imex:IM-28077|pubmed:30097533 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-25505061|imex:IM-28077-3 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000131126(gene)|ensembl:ENST00000598265(transcript)|go:"GO:0001669"(acrosomal vesicle)|go:"GO:0002080"(acrosomal membrane)|go:"GO:0005576"(extracellular region)|go:"GO:0005886"(plasma membrane)|go:"GO:0007339"(binding of sperm to zona pellucida)|go:"GO:0009566"(fertilization)|go:"GO:0030317"(flagellated sperm motility)|go:"GO:0044853"(plasma membrane raft)|go:"GO:0046658"(anchored component of plasma membrane)|go:"GO:1901317"(regulation of flagellated sperm motility)|interpro:IPR016054(Ly-6 antigen / uPA receptor -like)|rcsb pdb:7BPR|reactome:R-HSA-163125|refseq:NP_001123483.1|refseq:NP_113639.4 refseq:NP_001186701.1|refseq:NP_001186702.1|refseq:NP_001186703.1|refseq:NP_002781.2|ensembl:ENSG00000143106(gene)|ensembl:ENST00000271308(transcript)|go:"GO:0000502"(proteasome complex)|go:"GO:0004175"(endopeptidase activity)|go:"GO:0005576"(extracellular region)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005839"(proteasome core complex)|go:"GO:0010499"(proteasomal ubiquitin-independent protein catabolic process)|go:"GO:0019773"(proteasome core complex, alpha-subunit complex)|go:"GO:0034774"(secretory granule lumen)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0070062"(extracellular exosome)|go:"GO:1904813"(ficolin-1-rich granule lumen)|interpro:IPR000426(Proteasome alpha-subunit, conserved site)|interpro:IPR001353(20S proteasome, A and B subunits)|interpro:IPR023332|interpro:IPR029055|interpro:IPR033812|mint:P28066|rcsb pdb:4R3O|rcsb pdb:4R67|rcsb pdb:5A0Q|rcsb pdb:5GJQ|rcsb pdb:5GJR|rcsb pdb:5L4G|rcsb pdb:5LE5|rcsb pdb:5LEY|rcsb pdb:5LEX|rcsb pdb:5LEZ|rcsb pdb:5LF0|rcsb pdb:5LF1|rcsb pdb:5LF3|rcsb pdb:5LF4|rcsb pdb:5LF6|rcsb pdb:5LF7|rcsb pdb:5LN3|rcsb pdb:5M32|rcsb pdb:5T0C|rcsb pdb:5T0G|rcsb pdb:5T0H|rcsb pdb:5T0I|rcsb pdb:5T0J|rcsb pdb:5VFO|rcsb pdb:5VFP|rcsb pdb:5VFQ|rcsb pdb:5VFR|rcsb pdb:5VFS|rcsb pdb:5VFT|rcsb pdb:5VFU|rcsb pdb:6AVO|rcsb pdb:6E5B|rcsb pdb:6KWY|rcsb pdb:6MSB|rcsb pdb:6MSD|rcsb pdb:6MSE|rcsb pdb:6MSG|rcsb pdb:6MSH|rcsb pdb:6MSJ|rcsb pdb:6MSK|rcsb pdb:6R70|rcsb pdb:6REY|rcsb pdb:6RGQ|rcsb pdb:6WJD|rcsb pdb:6WJN|rcsb pdb:6XMJ|rcsb pdb:7AWE|reactome:R-HSA-1169091|reactome:R-HSA-1234176|reactome:R-HSA-1236974|reactome:R-HSA-1236978|reactome:R-HSA-174084|reactome:R-HSA-174113|reactome:R-HSA-174154|reactome:R-HSA-174178|reactome:R-HSA-174184|reactome:R-HSA-180534|reactome:R-HSA-180585|reactome:R-HSA-187577|reactome:R-HSA-195253|reactome:R-HSA-202424|reactome:R-HSA-211733|reactome:R-HSA-2467813|reactome:R-HSA-2871837|reactome:R-HSA-349425|reactome:R-HSA-350562|reactome:R-HSA-382556|reactome:R-HSA-450408|reactome:R-HSA-4608870|reactome:R-HSA-4641257|reactome:R-HSA-4641258|reactome:R-HSA-5358346|reactome:R-HSA-5362768|reactome:R-HSA-5607761|reactome:R-HSA-5607764|reactome:R-HSA-5610780|reactome:R-HSA-5610783|reactome:R-HSA-5610785|reactome:R-HSA-5632684|reactome:R-HSA-5658442|reactome:R-HSA-5668541|reactome:R-HSA-5676590|reactome:R-HSA-5678895|reactome:R-HSA-5687128|reactome:R-HSA-5689603|reactome:R-HSA-5689880|reactome:R-HSA-6798695|reactome:R-HSA-68827|reactome:R-HSA-68949|reactome:R-HSA-69017|reactome:R-HSA-69481|reactome:R-HSA-69601|reactome:R-HSA-75815|reactome:R-HSA-8852276|reactome:R-HSA-8854050|reactome:R-HSA-8932339|reactome:R-HSA-8939236|reactome:R-HSA-8939902|reactome:R-HSA-8941858|reactome:R-HSA-8948751|reactome:R-HSA-8951664|reactome:R-HSA-9010553|reactome:R-HSA-9020702|reactome:R-HSA-9604323|reactome:R-HSA-983168|dip:DIP-29368N - - - figure legend:Fig.2A,Supp Table S5|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-testis)|taxid:9606(Homo sapiens) - 2020/03/24 2021/11/30 rogid:ZE4tXTFi7lUCcIbCL4KHzY3a6xM9606 rogid:bfMG3npzVetUH1tahr2MAI4R+3g9606 rigid:/AFat0DrynAJ5ofEnoPSTThlxCE false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9BY14 uniprotkb:P61020 intact:EBI-12549378|ensembl:ENSP00000472769|uniprotkb:Q7L5R2|uniprotkb:Q9BPY7 intact:EBI-399401|uniprotkb:P35239|uniprotkb:P35277|uniprotkb:Q6PIK9|uniprotkb:Q86TH0|uniprotkb:Q8IXL2|uniprotkb:A8K982|uniprotkb:B4DKD7|ensembl:ENSP00000353444|ensembl:ENSP00000450168 psi-mi:tx101_human(display_long)|uniprotkb:TEX101(gene name)|psi-mi:TEX101(display_short)|uniprotkb:Cell surface receptor NYD-SP8(gene name synonym)|uniprotkb:SGRG(gene name synonym)|uniprotkb:Scleroderma-associated autoantigen(gene name synonym)|uniprotkb:Spermatogenesis-related gene protein(gene name synonym)|uniprotkb:UNQ867/PRO1884(orf name) psi-mi:rab5b_human(display_long)|uniprotkb:RAB5B(gene name)|psi-mi:RAB5B(display_short) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Schiza et al. (2018) imex:IM-28077|pubmed:30097533 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-25505061|imex:IM-28077-3 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000131126(gene)|ensembl:ENST00000598265(transcript)|go:"GO:0001669"(acrosomal vesicle)|go:"GO:0002080"(acrosomal membrane)|go:"GO:0005576"(extracellular region)|go:"GO:0005886"(plasma membrane)|go:"GO:0007339"(binding of sperm to zona pellucida)|go:"GO:0009566"(fertilization)|go:"GO:0030317"(flagellated sperm motility)|go:"GO:0044853"(plasma membrane raft)|go:"GO:0046658"(anchored component of plasma membrane)|go:"GO:1901317"(regulation of flagellated sperm motility)|interpro:IPR016054(Ly-6 antigen / uPA receptor -like)|rcsb pdb:7BPR|reactome:R-HSA-163125|refseq:NP_001123483.1|refseq:NP_113639.4 refseq:NP_002859.1|refseq:NP_001238965.1|refseq:XP_005269108.1|refseq:XP_005269109.1|refseq:NP_001238966.1|ensembl:ENSG00000111540(gene)|ensembl:ENST00000360299(transcript)|ensembl:ENST00000553116(transcript)|go:"GO:0003924"(GTPase activity)|go:"GO:0003925"(G protein activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005768"(endosome)|go:"GO:0005769"(early endosome)|go:"GO:0005886"(plasma membrane)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006897"(endocytosis)|go:"GO:0012505"(endomembrane system)|go:"GO:0016020"(membrane)|go:"GO:0019003"(GDP binding)|go:"GO:0019882"(antigen processing and presentation)|go:"GO:0030100"(regulation of endocytosis)|go:"GO:0030139"(endocytic vesicle)|go:"GO:0030667"(secretory granule membrane)|go:"GO:0030742"(GTP-dependent protein binding)|go:"GO:0031901"(early endosome membrane)|go:"GO:0042470"(melanosome)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0048227"(plasma membrane to endosome transport)|go:"GO:0070062"(extracellular exosome)|interpro:IPR001806(Ras GTPase)|interpro:IPR005225(Small GTP-binding protein)|interpro:IPR027417|rcsb pdb:2HEI|reactome:R-HSA-6798695|reactome:R-HSA-8854214|reactome:R-HSA-8856828|reactome:R-HSA-8873719|reactome:R-HSA-8876198 - - - figure legend:Fig.2A,Supp Table S5|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-testis)|taxid:9606(Homo sapiens) - 2020/03/24 2021/11/30 rogid:ZE4tXTFi7lUCcIbCL4KHzY3a6xM9606 rogid:jm+x3SYDL+i+/BrDFnp44kxlHUM9606 rigid:/AFat0DrynAJ5ofEnoPSTThlxCE false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9BY14 uniprotkb:P42766 intact:EBI-12549378|ensembl:ENSP00000472769|uniprotkb:Q7L5R2|uniprotkb:Q9BPY7 intact:EBI-356819|uniprotkb:Q4VBY5|uniprotkb:Q9BYF4|uniprotkb:Q5JTN5|uniprotkb:Q6IBC7|uniprotkb:Q96QJ7|uniprotkb:A8K4V7|ensembl:ENSP00000259469 psi-mi:tx101_human(display_long)|uniprotkb:TEX101(gene name)|psi-mi:TEX101(display_short)|uniprotkb:Cell surface receptor NYD-SP8(gene name synonym)|uniprotkb:SGRG(gene name synonym)|uniprotkb:Scleroderma-associated autoantigen(gene name synonym)|uniprotkb:Spermatogenesis-related gene protein(gene name synonym)|uniprotkb:UNQ867/PRO1884(orf name) psi-mi:rl35_human(display_long)|uniprotkb:RPL35(gene name)|psi-mi:RPL35(display_short)|uniprotkb:Large ribosomal subunit protein uL29(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Schiza et al. (2018) imex:IM-28077|pubmed:30097533 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-25505061|imex:IM-28077-3 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000131126(gene)|ensembl:ENST00000598265(transcript)|go:"GO:0001669"(acrosomal vesicle)|go:"GO:0002080"(acrosomal membrane)|go:"GO:0005576"(extracellular region)|go:"GO:0005886"(plasma membrane)|go:"GO:0007339"(binding of sperm to zona pellucida)|go:"GO:0009566"(fertilization)|go:"GO:0030317"(flagellated sperm motility)|go:"GO:0044853"(plasma membrane raft)|go:"GO:0046658"(anchored component of plasma membrane)|go:"GO:1901317"(regulation of flagellated sperm motility)|interpro:IPR016054(Ly-6 antigen / uPA receptor -like)|rcsb pdb:7BPR|reactome:R-HSA-163125|refseq:NP_001123483.1|refseq:NP_113639.4 refseq:NP_009140.1|ensembl:ENSG00000136942(gene)|ensembl:ENST00000348462(transcript)|go:"GO:0000463"("maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)")|go:"GO:0002181"(cytoplasmic translation)|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0006412"(translation)|go:"GO:0016020"(membrane)|go:"GO:0022625"(cytosolic large ribosomal subunit)|go:"GO:0022626"(cytosolic ribosome)|interpro:IPR001854(Ribosomal protein L29)|interpro:IPR018254|interpro:IPR036049|mint:P42766|rcsb pdb:4UG0|rcsb pdb:4V6X|rcsb pdb:5AJ0|rcsb pdb:5LKS|rcsb pdb:5T2C|rcsb pdb:6EK0|rcsb pdb:6IP5|rcsb pdb:6IP6|rcsb pdb:6IP8|rcsb pdb:6LQM|rcsb pdb:6LSR|rcsb pdb:6LSS|rcsb pdb:6LU8|rcsb pdb:6OLE|rcsb pdb:6OLF|rcsb pdb:6OLG|rcsb pdb:6OLI|rcsb pdb:6OLZ|rcsb pdb:6OM0|rcsb pdb:6OM7|rcsb pdb:6QZP|rcsb pdb:6SXO|rcsb pdb:6W6L|rcsb pdb:6XA1|rcsb pdb:6Y0G|rcsb pdb:6Y2L|rcsb pdb:6Y57|rcsb pdb:6Y6X|rcsb pdb:6Z6L|rcsb pdb:6Z6M|rcsb pdb:6Z6N|rcsb pdb:6ZM7|rcsb pdb:6ZME|rcsb pdb:6ZMI|rcsb pdb:6ZMO|rcsb pdb:7BHP|reactome:R-HSA-156827|reactome:R-HSA-156902|reactome:R-HSA-1799339|reactome:R-HSA-192823|reactome:R-HSA-2408557|reactome:R-HSA-6791226|reactome:R-HSA-72689|reactome:R-HSA-72706|reactome:R-HSA-72764|reactome:R-HSA-9010553|reactome:R-HSA-9633012|reactome:R-HSA-975956|reactome:R-HSA-975957 - - - figure legend:Fig.2A,Supp Table S5|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-testis)|taxid:9606(Homo sapiens) - 2020/03/24 2021/11/30 rogid:ZE4tXTFi7lUCcIbCL4KHzY3a6xM9606 rogid:jhzt7gCff2vdUb1Ff/VTBF698Pg9606 rigid:/AFat0DrynAJ5ofEnoPSTThlxCE false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9BY14 uniprotkb:P61160 intact:EBI-12549378|ensembl:ENSP00000472769|uniprotkb:Q7L5R2|uniprotkb:Q9BPY7 intact:EBI-353580|ensembl:ENSP00000260641|uniprotkb:O15142|uniprotkb:Q96C82|uniprotkb:B2RCP5|uniprotkb:D6W5F4|uniprotkb:E9PF41 psi-mi:tx101_human(display_long)|uniprotkb:TEX101(gene name)|psi-mi:TEX101(display_short)|uniprotkb:Cell surface receptor NYD-SP8(gene name synonym)|uniprotkb:SGRG(gene name synonym)|uniprotkb:Scleroderma-associated autoantigen(gene name synonym)|uniprotkb:Spermatogenesis-related gene protein(gene name synonym)|uniprotkb:UNQ867/PRO1884(orf name) psi-mi:arp2_human(display_long)|uniprotkb:ACTR2(gene name)|psi-mi:ACTR2(display_short)|uniprotkb:ARP2(gene name synonym)|uniprotkb:Actin-like protein 2(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Schiza et al. (2018) imex:IM-28077|pubmed:30097533 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-25505061|imex:IM-28077-3 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000131126(gene)|ensembl:ENST00000598265(transcript)|go:"GO:0001669"(acrosomal vesicle)|go:"GO:0002080"(acrosomal membrane)|go:"GO:0005576"(extracellular region)|go:"GO:0005886"(plasma membrane)|go:"GO:0007339"(binding of sperm to zona pellucida)|go:"GO:0009566"(fertilization)|go:"GO:0030317"(flagellated sperm motility)|go:"GO:0044853"(plasma membrane raft)|go:"GO:0046658"(anchored component of plasma membrane)|go:"GO:1901317"(regulation of flagellated sperm motility)|interpro:IPR016054(Ly-6 antigen / uPA receptor -like)|rcsb pdb:7BPR|reactome:R-HSA-163125|refseq:NP_001123483.1|refseq:NP_113639.4 ensembl:ENSG00000138071(gene)|ensembl:ENST00000260641(transcript)|go:"GO:0003779"(actin binding)|go:"GO:0005200"(structural constituent of cytoskeleton)|go:"GO:0005524"(ATP binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005885"(Arp2/3 protein complex)|go:"GO:0005925"(focal adhesion)|go:"GO:0007163"(establishment or maintenance of cell polarity)|go:"GO:0008306"(associative learning)|go:"GO:0008356"(asymmetric cell division)|go:"GO:0010592"(positive regulation of lamellipodium assembly)|go:"GO:0014069"(postsynaptic density)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0016020"(membrane)|go:"GO:0016344"(meiotic chromosome movement towards spindle pole)|go:"GO:0016482"(cytosolic transport)|go:"GO:0030027"(lamellipodium)|go:"GO:0030478"(actin cap)|go:"GO:0033206"(meiotic cytokinesis)|go:"GO:0034314"(Arp2/3 complex-mediated actin nucleation)|go:"GO:0035578"(azurophil granule lumen)|go:"GO:0035861"(site of double-strand break)|go:"GO:0035902"(response to immobilization stress)|go:"GO:0035984"(cellular response to trichostatin A)|go:"GO:0045471"(response to ethanol)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0051653"(spindle localization)|go:"GO:0060271"(cilium assembly)|go:"GO:0061003"(positive regulation of dendritic spine morphogenesis)|go:"GO:0061825"(podosome core)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071346"(cellular response to interferon-gamma)|go:"GO:1904813"(ficolin-1-rich granule lumen)|refseq:NP_001005386.1|refseq:NP_005713.1|go:"GO:1905168"(positive regulation of double-strand break repair via homologous recombination)|interpro:IPR004000(Actin/actin-like)|interpro:IPR020902|interpro:IPR043129|mint:P61160|rcsb pdb:6UHC|rcsb pdb:6YW6|rcsb pdb:6YW7|reactome:R-HSA-2029482|reactome:R-HSA-3928662|reactome:R-HSA-5663213|reactome:R-HSA-6798695|reactome:R-HSA-8856828|reactome:R-HSA-9664422|dip:DIP-33165N - - - figure legend:Fig.2A,Supp Table S5|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-testis)|taxid:9606(Homo sapiens) - 2020/03/24 2021/11/30 rogid:ZE4tXTFi7lUCcIbCL4KHzY3a6xM9606 rogid:URQsZpIsMtsFZAnpLYDDvgKcPqA9606 rigid:/AFat0DrynAJ5ofEnoPSTThlxCE false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9BY14 uniprotkb:P50454 intact:EBI-12549378|ensembl:ENSP00000472769|uniprotkb:Q7L5R2|uniprotkb:Q9BPY7 intact:EBI-350723|uniprotkb:P29043|uniprotkb:Q5XPB4|uniprotkb:Q6NSJ6|uniprotkb:Q8IY96|uniprotkb:Q9NP88|uniprotkb:B3KVJ3|ensembl:ENSP00000350894|ensembl:ENSP00000434412|ensembl:ENSP00000434657 psi-mi:tx101_human(display_long)|uniprotkb:TEX101(gene name)|psi-mi:TEX101(display_short)|uniprotkb:Cell surface receptor NYD-SP8(gene name synonym)|uniprotkb:SGRG(gene name synonym)|uniprotkb:Scleroderma-associated autoantigen(gene name synonym)|uniprotkb:Spermatogenesis-related gene protein(gene name synonym)|uniprotkb:UNQ867/PRO1884(orf name) psi-mi:serph_human(display_long)|uniprotkb:SERPINH1(gene name)|psi-mi:SERPINH1(display_short)|uniprotkb:CBP2(gene name synonym)|uniprotkb:Collagen-binding protein(gene name synonym)|uniprotkb:47 kDa heat shock protein(gene name synonym)|uniprotkb:Rheumatoid arthritis-related antigen RA-A47(gene name synonym)|uniprotkb:Arsenic-transactivated protein 3(gene name synonym)|uniprotkb:Cell proliferation-inducing gene 14 protein(gene name synonym)|uniprotkb:CBP1(gene name synonym)|uniprotkb:HSP47(gene name synonym)|uniprotkb:SERPINH2(gene name synonym)|uniprotkb:PIG14(orf name) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Schiza et al. (2018) imex:IM-28077|pubmed:30097533 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-25505061|imex:IM-28077-3 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000131126(gene)|ensembl:ENST00000598265(transcript)|go:"GO:0001669"(acrosomal vesicle)|go:"GO:0002080"(acrosomal membrane)|go:"GO:0005576"(extracellular region)|go:"GO:0005886"(plasma membrane)|go:"GO:0007339"(binding of sperm to zona pellucida)|go:"GO:0009566"(fertilization)|go:"GO:0030317"(flagellated sperm motility)|go:"GO:0044853"(plasma membrane raft)|go:"GO:0046658"(anchored component of plasma membrane)|go:"GO:1901317"(regulation of flagellated sperm motility)|interpro:IPR016054(Ly-6 antigen / uPA receptor -like)|rcsb pdb:7BPR|reactome:R-HSA-163125|refseq:NP_001123483.1|refseq:NP_113639.4 refseq:NP_001193943.1|refseq:NP_001226.2|go:"GO:0003723"(RNA binding)|go:"GO:0004867"(serine-type endopeptidase inhibitor activity)|go:"GO:0005518"(collagen binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005788"(endoplasmic reticulum lumen)|go:"GO:0005793"(endoplasmic reticulum-Golgi intermediate compartment)|go:"GO:0006986"(response to unfolded protein)|go:"GO:0010951"(negative regulation of endopeptidase activity)|go:"GO:0030199"(collagen fibril organization)|go:"GO:0032964"(collagen biosynthetic process)|go:"GO:0045121"(membrane raft)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0051604"(protein maturation)|go:"GO:0062023"(collagen-containing extracellular matrix)|interpro:IPR000215(Protease inhibitor I4, serpin)|interpro:IPR023795|interpro:IPR023796|interpro:IPR033547|interpro:IPR033830|interpro:IPR036186|interpro:IPR042178|interpro:IPR042185|mint:P50454|reactome:R-HSA-1650814|ensembl:ENSG00000149257(gene)|ensembl:ENST00000358171(transcript)|ensembl:ENST00000524558(transcript)|ensembl:ENST00000533603(transcript)|go:"GO:0003433"(chondrocyte development involved in endochondral bone morphogenesis)|refseq:XP_011543629.1 - - - figure legend:Fig.2A,Supp Table S5|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-testis)|taxid:9606(Homo sapiens) - 2020/03/24 2021/11/30 rogid:ZE4tXTFi7lUCcIbCL4KHzY3a6xM9606 rogid:cO3NR2hb0NyOs99Sq1aODePlDR09606 rigid:/AFat0DrynAJ5ofEnoPSTThlxCE false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9BY14 uniprotkb:Q9UNM6 intact:EBI-12549378|ensembl:ENSP00000472769|uniprotkb:Q7L5R2|uniprotkb:Q9BPY7 intact:EBI-356070|uniprotkb:O75831|uniprotkb:Q9UNV3|uniprotkb:Q53XU2|intact:EBI-1058479|uniprotkb:B3KT15|ensembl:ENSP00000436186 psi-mi:tx101_human(display_long)|uniprotkb:TEX101(gene name)|psi-mi:TEX101(display_short)|uniprotkb:Cell surface receptor NYD-SP8(gene name synonym)|uniprotkb:SGRG(gene name synonym)|uniprotkb:Scleroderma-associated autoantigen(gene name synonym)|uniprotkb:Spermatogenesis-related gene protein(gene name synonym)|uniprotkb:UNQ867/PRO1884(orf name) psi-mi:psd13_human(display_long)|uniprotkb:PSMD13(gene name)|psi-mi:PSMD13(display_short)|uniprotkb:26S proteasome regulatory subunit S11(gene name synonym)|uniprotkb:26S proteasome regulatory subunit p40.5(gene name synonym)|uniprotkb:26S proteasome regulatory subunit RPN9(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Schiza et al. (2018) imex:IM-28077|pubmed:30097533 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-25505061|imex:IM-28077-3 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000131126(gene)|ensembl:ENST00000598265(transcript)|go:"GO:0001669"(acrosomal vesicle)|go:"GO:0002080"(acrosomal membrane)|go:"GO:0005576"(extracellular region)|go:"GO:0005886"(plasma membrane)|go:"GO:0007339"(binding of sperm to zona pellucida)|go:"GO:0009566"(fertilization)|go:"GO:0030317"(flagellated sperm motility)|go:"GO:0044853"(plasma membrane raft)|go:"GO:0046658"(anchored component of plasma membrane)|go:"GO:1901317"(regulation of flagellated sperm motility)|interpro:IPR016054(Ly-6 antigen / uPA receptor -like)|rcsb pdb:7BPR|reactome:R-HSA-163125|refseq:NP_001123483.1|refseq:NP_113639.4 refseq:NP_002808.3|refseq:NP_787128.2|dip:DIP-27576N|rcsb pdb:6WJD|rcsb pdb:6WJN|reactome:R-HSA-1169091|reactome:R-HSA-1234176|reactome:R-HSA-1236974|reactome:R-HSA-1236978|rcsb pdb:6MSK|reactome:R-HSA-174084|reactome:R-HSA-174113|reactome:R-HSA-174154|reactome:R-HSA-174178|reactome:R-HSA-174184|reactome:R-HSA-180534|reactome:R-HSA-180585|reactome:R-HSA-187577|reactome:R-HSA-195253|reactome:R-HSA-202424|reactome:R-HSA-211733|reactome:R-HSA-2467813|reactome:R-HSA-2871837|reactome:R-HSA-349425|reactome:R-HSA-350562|reactome:R-HSA-382556|reactome:R-HSA-450408|reactome:R-HSA-4608870|reactome:R-HSA-4641257|reactome:R-HSA-4641258|reactome:R-HSA-5358346|reactome:R-HSA-5362768|reactome:R-HSA-5607761|reactome:R-HSA-5607764|reactome:R-HSA-5610780|reactome:R-HSA-5610783|reactome:R-HSA-5610785|reactome:R-HSA-5632684|reactome:R-HSA-5658442|reactome:R-HSA-5668541|reactome:R-HSA-5676590|reactome:R-HSA-5678895|reactome:R-HSA-5687128|reactome:R-HSA-5689603|reactome:R-HSA-5689880|reactome:R-HSA-6798695|reactome:R-HSA-68827|reactome:R-HSA-68949|reactome:R-HSA-69017|reactome:R-HSA-69481|reactome:R-HSA-69601|reactome:R-HSA-75815|reactome:R-HSA-8852276|reactome:R-HSA-8854050|reactome:R-HSA-8932339|reactome:R-HSA-8939236|reactome:R-HSA-8939902|reactome:R-HSA-8941858|reactome:R-HSA-8948751|reactome:R-HSA-8951664|reactome:R-HSA-9010553|reactome:R-HSA-9020702|reactome:R-HSA-9604323|reactome:R-HSA-983168|ensembl:ENSG00000185627(gene)|ensembl:ENST00000532097(transcript)|go:"GO:0000502"(proteasome complex)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005576"(extracellular region)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005838"(proteasome regulatory particle)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0007127"(meiosis I)|go:"GO:0008541"(proteasome regulatory particle, lid subcomplex)|go:"GO:0016020"(membrane)|go:"GO:0022624"(proteasome accessory complex)|go:"GO:0034774"(secretory granule lumen)|go:"GO:0043248"(proteasome assembly)|go:"GO:1904813"(ficolin-1-rich granule lumen)|interpro:IPR000717(Proteasome component region PCI)|interpro:IPR035298|interpro:IPR036390|mint:Q9UNM6|rcsb pdb:5GJQ|rcsb pdb:5GJR|rcsb pdb:5L4K|rcsb pdb:5LN3|rcsb pdb:5M32|rcsb pdb:5T0C|rcsb pdb:5T0G|rcsb pdb:5T0H|rcsb pdb:5T0I|rcsb pdb:5T0J|rcsb pdb:5VFP|rcsb pdb:5VFQ|rcsb pdb:5VFR|rcsb pdb:5VFS|rcsb pdb:5VFT|rcsb pdb:5VFU|rcsb pdb:5VGZ|rcsb pdb:5VHF|rcsb pdb:5VHH|rcsb pdb:5VHI|rcsb pdb:5VHS|rcsb pdb:6MSB|rcsb pdb:6MSD|rcsb pdb:6MSE|rcsb pdb:6MSG|rcsb pdb:6MSH|rcsb pdb:6MSJ - - - figure legend:Fig.2A,Supp Table S5|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-testis)|taxid:9606(Homo sapiens) - 2020/03/24 2021/11/30 rogid:ZE4tXTFi7lUCcIbCL4KHzY3a6xM9606 rogid:iOxE62MMeGx+aqsrir/LukJqeho9606 rigid:/AFat0DrynAJ5ofEnoPSTThlxCE false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9BY14 uniprotkb:Q9Y624 intact:EBI-12549378|ensembl:ENSP00000472769|uniprotkb:Q7L5R2|uniprotkb:Q9BPY7 intact:EBI-742600|uniprotkb:B7Z941|ensembl:ENSP00000357005 psi-mi:tx101_human(display_long)|uniprotkb:TEX101(gene name)|psi-mi:TEX101(display_short)|uniprotkb:Cell surface receptor NYD-SP8(gene name synonym)|uniprotkb:SGRG(gene name synonym)|uniprotkb:Scleroderma-associated autoantigen(gene name synonym)|uniprotkb:Spermatogenesis-related gene protein(gene name synonym)|uniprotkb:UNQ867/PRO1884(orf name) psi-mi:jam1_human(display_long)|uniprotkb:Junctional adhesion molecule 1(gene name synonym)|uniprotkb:Platelet adhesion molecule 1(gene name synonym)|uniprotkb:Platelet F11 receptor(gene name synonym)|uniprotkb:F11R(gene name)|psi-mi:F11R(display_short)|uniprotkb:JAM1(gene name synonym)|uniprotkb:JCAM(gene name synonym)|uniprotkb:UNQ264/PRO301(orf name) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Schiza et al. (2018) imex:IM-28077|pubmed:30097533 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-25505061|imex:IM-28077-3 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000131126(gene)|ensembl:ENST00000598265(transcript)|go:"GO:0001669"(acrosomal vesicle)|go:"GO:0002080"(acrosomal membrane)|go:"GO:0005576"(extracellular region)|go:"GO:0005886"(plasma membrane)|go:"GO:0007339"(binding of sperm to zona pellucida)|go:"GO:0009566"(fertilization)|go:"GO:0030317"(flagellated sperm motility)|go:"GO:0044853"(plasma membrane raft)|go:"GO:0046658"(anchored component of plasma membrane)|go:"GO:1901317"(regulation of flagellated sperm motility)|interpro:IPR016054(Ly-6 antigen / uPA receptor -like)|rcsb pdb:7BPR|reactome:R-HSA-163125|refseq:NP_001123483.1|refseq:NP_113639.4 refseq:NP_058642.1|ensembl:ENSG00000158769(gene)|ensembl:ENST00000368026(transcript)|go:"GO:0001618"(virus receptor activity)|go:"GO:0001817"(regulation of cytokine production)|go:"GO:0005178"(integrin binding)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005923"(bicellular tight junction)|go:"GO:0006954"(inflammatory response)|go:"GO:0007159"(leukocyte cell-cell adhesion)|go:"GO:0008360"(regulation of cell shape)|go:"GO:0045296"(cadherin binding)|go:"GO:0045777"(positive regulation of blood pressure)|go:"GO:0050892"(intestinal absorption)|go:"GO:0051493"(regulation of cytoskeleton organization)|go:"GO:0051497"(negative regulation of stress fiber assembly)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070160"(tight junction)|go:"GO:0071260"(cellular response to mechanical stimulus)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0090557"(establishment of endothelial intestinal barrier)|go:"GO:0090559"(regulation of membrane permeability)|go:"GO:0098609"(cell-cell adhesion)|go:"GO:1901731"(positive regulation of platelet aggregation)|go:"GO:1902396"(protein localization to bicellular tight junction)|go:"GO:1903142"(positive regulation of establishment of endothelial barrier)|go:"GO:2000249"(regulation of actin cytoskeleton reorganization)|go:"GO:2000810"(regulation of bicellular tight junction assembly)|interpro:IPR003598(Immunoglobulin subtype 2)|interpro:IPR003599(Immunoglobulin subtype)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR013106(Immunoglobulin V-set)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR036179|interpro:IPR042456|mint:Q9Y624|rcsb pdb:1NBQ|rcsb pdb:3EOY|rcsb pdb:3TSZ|rcsb pdb:4ODB|reactome:R-HSA-202733|reactome:R-HSA-216083|reactome:R-HSA-2173791|reactome:R-HSA-420029|go:"GO:0016021"(integral component of membrane)|go:"GO:0030054"(cell junction)|go:"GO:0030165"(PDZ domain binding)|go:"GO:0031032"(actomyosin structure organization)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0032956"(regulation of actin cytoskeleton organization)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034260"(negative regulation of GTPase activity)|go:"GO:0035025"(positive regulation of Rho protein signal transduction)|go:"GO:0035633"(maintenance of blood-brain barrier)|go:"GO:0035683"(memory T cell extravasation)|go:"GO:0036057"(slit diaphragm)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043547"(positive regulation of GTPase activity)|go:"GO:0009314"(response to radiation)|refseq:NP_001335020.1 - - - figure legend:Fig.2A,Supp Table S5|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-testis)|taxid:9606(Homo sapiens) - 2020/03/24 2021/11/30 rogid:ZE4tXTFi7lUCcIbCL4KHzY3a6xM9606 rogid:9TaktSbIwjn9jMYlv86aB44hwes9606 rigid:/AFat0DrynAJ5ofEnoPSTThlxCE false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9BY14 uniprotkb:O43399 intact:EBI-12549378|ensembl:ENSP00000472769|uniprotkb:Q7L5R2|uniprotkb:Q9BPY7 intact:EBI-782604|uniprotkb:Q5U0E0|uniprotkb:Q5JWU6|uniprotkb:Q9H3Z6|intact:EBI-1043547|uniprotkb:O43398|uniprotkb:Q5JWU5|uniprotkb:Q5JWU8|uniprotkb:E1P5G7|uniprotkb:B4DPJ6|ensembl:ENSP00000343547 psi-mi:tx101_human(display_long)|uniprotkb:TEX101(gene name)|psi-mi:TEX101(display_short)|uniprotkb:Cell surface receptor NYD-SP8(gene name synonym)|uniprotkb:SGRG(gene name synonym)|uniprotkb:Scleroderma-associated autoantigen(gene name synonym)|uniprotkb:Spermatogenesis-related gene protein(gene name synonym)|uniprotkb:UNQ867/PRO1884(orf name) psi-mi:tpd54_human(display_long)|uniprotkb:Tumor protein D52-like 2(gene name synonym)|uniprotkb:TPD52L2(gene name)|psi-mi:TPD52L2(display_short) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Schiza et al. (2018) imex:IM-28077|pubmed:30097533 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-25505061|imex:IM-28077-3 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000131126(gene)|ensembl:ENST00000598265(transcript)|go:"GO:0001669"(acrosomal vesicle)|go:"GO:0002080"(acrosomal membrane)|go:"GO:0005576"(extracellular region)|go:"GO:0005886"(plasma membrane)|go:"GO:0007339"(binding of sperm to zona pellucida)|go:"GO:0009566"(fertilization)|go:"GO:0030317"(flagellated sperm motility)|go:"GO:0044853"(plasma membrane raft)|go:"GO:0046658"(anchored component of plasma membrane)|go:"GO:1901317"(regulation of flagellated sperm motility)|interpro:IPR016054(Ly-6 antigen / uPA receptor -like)|rcsb pdb:7BPR|reactome:R-HSA-163125|refseq:NP_001123483.1|refseq:NP_113639.4 refseq:NP_001230821.1|refseq:NP_003279.2|refseq:NP_955393.1|refseq:NP_955395.1|refseq:NP_955394.1|refseq:NP_955392.1|ensembl:ENSG00000101150(gene)|ensembl:ENST00000346249(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005975"(carbohydrate metabolic process)|go:"GO:0042127"(regulation of cell population proliferation)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0048471"(perinuclear region of cytoplasm)|interpro:IPR007327(Tumor protein D52)|interpro:IPR012341(Six-hairpin glycosidase)|mint:O43399 - - - figure legend:Fig.2A,Supp Table S5|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-testis)|taxid:9606(Homo sapiens) - 2020/03/24 2021/11/30 rogid:ZE4tXTFi7lUCcIbCL4KHzY3a6xM9606 rogid:asqRlZnmqIzXCJ5TAHjxKcj046g9606 rigid:/AFat0DrynAJ5ofEnoPSTThlxCE false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9BY14 uniprotkb:Q9H4B8 intact:EBI-12549378|ensembl:ENSP00000472769|uniprotkb:Q7L5R2|uniprotkb:Q9BPY7 intact:EBI-20843342|ensembl:ENSP00000268793|uniprotkb:B3KQ48|uniprotkb:Q6PEZ5|uniprotkb:Q6UXE4 psi-mi:tx101_human(display_long)|uniprotkb:TEX101(gene name)|psi-mi:TEX101(display_short)|uniprotkb:Cell surface receptor NYD-SP8(gene name synonym)|uniprotkb:SGRG(gene name synonym)|uniprotkb:Scleroderma-associated autoantigen(gene name synonym)|uniprotkb:Spermatogenesis-related gene protein(gene name synonym)|uniprotkb:UNQ867/PRO1884(orf name) psi-mi:dpep3_human(display_long)|uniprotkb:DPEP3(gene name)|psi-mi:DPEP3(display_short)|uniprotkb:UNQ834/PRO1772(orf name) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Schiza et al. (2018) imex:IM-28077|pubmed:30097533 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-25505061|imex:IM-28077-3 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000131126(gene)|ensembl:ENST00000598265(transcript)|go:"GO:0001669"(acrosomal vesicle)|go:"GO:0002080"(acrosomal membrane)|go:"GO:0005576"(extracellular region)|go:"GO:0005886"(plasma membrane)|go:"GO:0007339"(binding of sperm to zona pellucida)|go:"GO:0009566"(fertilization)|go:"GO:0030317"(flagellated sperm motility)|go:"GO:0044853"(plasma membrane raft)|go:"GO:0046658"(anchored component of plasma membrane)|go:"GO:1901317"(regulation of flagellated sperm motility)|interpro:IPR016054(Ly-6 antigen / uPA receptor -like)|rcsb pdb:7BPR|reactome:R-HSA-163125|refseq:NP_001123483.1|refseq:NP_113639.4 ensembl:ENSG00000141096(gene)|ensembl:ENST00000268793(transcript)|go:"GO:0001669"(acrosomal vesicle)|go:"GO:0005886"(plasma membrane)|go:"GO:0016805"(dipeptidase activity)|go:"GO:0031225"(anchored component of membrane)|go:"GO:0046872"(metal ion binding)|go:"GO:0070573"(metallodipeptidase activity)|interpro:IPR000180(Peptidase M19, renal dipeptidase, active site)|interpro:IPR008257(Peptidase M19, renal dipeptidase)|interpro:IPR028531|interpro:IPR032466|rcsb pdb:6VGO|rcsb pdb:6VGR|reactome:R-HSA-2142691|reactome:R-HSA-5423646|reactome:R-HSA-9664535|refseq:NP_001123230.1|refseq:NP_071752.3 - - - figure legend:Fig.2A,Supp Table S5|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-testis)|taxid:9606(Homo sapiens) - 2020/03/24 2021/11/30 rogid:ZE4tXTFi7lUCcIbCL4KHzY3a6xM9606 rogid:wSsO6DP0LPkeh39DF/dAvEktuTE9606 rigid:/AFat0DrynAJ5ofEnoPSTThlxCE false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9BY14 uniprotkb:P11310 intact:EBI-12549378|ensembl:ENSP00000472769|uniprotkb:Q7L5R2|uniprotkb:Q9BPY7 intact:EBI-514381|uniprotkb:Q9NYF1|uniprotkb:Q5T4U4|ensembl:ENSP00000359878 psi-mi:tx101_human(display_long)|uniprotkb:TEX101(gene name)|psi-mi:TEX101(display_short)|uniprotkb:Cell surface receptor NYD-SP8(gene name synonym)|uniprotkb:SGRG(gene name synonym)|uniprotkb:Scleroderma-associated autoantigen(gene name synonym)|uniprotkb:Spermatogenesis-related gene protein(gene name synonym)|uniprotkb:UNQ867/PRO1884(orf name) psi-mi:acadm_human(display_long)|uniprotkb:Medium chain acyl-CoA dehydrogenase(gene name synonym)|uniprotkb:ACADM(gene name)|psi-mi:ACADM(display_short) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Schiza et al. (2018) imex:IM-28077|pubmed:30097533 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-25505061|imex:IM-28077-3 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000131126(gene)|ensembl:ENST00000598265(transcript)|go:"GO:0001669"(acrosomal vesicle)|go:"GO:0002080"(acrosomal membrane)|go:"GO:0005576"(extracellular region)|go:"GO:0005886"(plasma membrane)|go:"GO:0007339"(binding of sperm to zona pellucida)|go:"GO:0009566"(fertilization)|go:"GO:0030317"(flagellated sperm motility)|go:"GO:0044853"(plasma membrane raft)|go:"GO:0046658"(anchored component of plasma membrane)|go:"GO:1901317"(regulation of flagellated sperm motility)|interpro:IPR016054(Ly-6 antigen / uPA receptor -like)|rcsb pdb:7BPR|reactome:R-HSA-163125|refseq:NP_001123483.1|refseq:NP_113639.4 refseq:NP_000007.1|refseq:NP_001120800.1|dip:DIP-34281N|ensembl:ENSG00000117054(gene)|ensembl:ENST00000370841(transcript)|go:"GO:0001889"(liver development)|go:"GO:0003995"(acyl-CoA dehydrogenase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005739"(mitochondrion)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0005978"(glycogen biosynthetic process)|go:"GO:0006111"(regulation of gluconeogenesis)|go:"GO:0006635"(fatty acid beta-oxidation)|go:"GO:0009409"(response to cold)|go:"GO:0009791"(post-embryonic development)|go:"GO:0019254"(carnitine metabolic process, CoA-linked)|go:"GO:0030424"(axon)|go:"GO:0031966"(mitochondrial membrane)|go:"GO:0033539"(fatty acid beta-oxidation using acyl-CoA dehydrogenase)|go:"GO:0042594"(response to starvation)|go:"GO:0042802"(identical protein binding)|go:"GO:0045329"(carnitine biosynthetic process)|go:"GO:0050660"(flavin adenine dinucleotide binding)|go:"GO:0051791"(medium-chain fatty acid metabolic process)|go:"GO:0051793"(medium-chain fatty acid catabolic process)|go:"GO:0055007"(cardiac muscle cell differentiation)|go:"GO:0070991"(medium-chain-acyl-CoA dehydrogenase activity)|interpro:IPR006089(Acyl-CoA dehydrogenase, conserved site)|interpro:IPR006091(Acyl-CoA dehydrogenase/oxidase, central region)|interpro:IPR009075(Acyl-CoA dehydrogenase/oxidase C-terminal)|interpro:IPR009100(Acyl-CoA dehydrogenase/oxidase, middle and N-terminal)|interpro:IPR013786(Acyl-CoA dehydrogenase/oxidase, N-terminal)|interpro:IPR034180|interpro:IPR036250|interpro:IPR037069|mint:P11310|rcsb pdb:1EGC|rcsb pdb:1EGD|rcsb pdb:1EGE|rcsb pdb:1T9G|rcsb pdb:2A1T|rcsb pdb:4P13|reactome:R-HSA-1989781|reactome:R-HSA-77288|reactome:R-HSA-77346|reactome:R-HSA-77348 - - - figure legend:Fig.2A,Supp Table S5|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-testis)|taxid:9606(Homo sapiens) - 2020/03/24 2021/11/30 rogid:ZE4tXTFi7lUCcIbCL4KHzY3a6xM9606 rogid:rfmTmYKNQr6R6ikvfYovZIctoz49606 rigid:/AFat0DrynAJ5ofEnoPSTThlxCE false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9BY14 uniprotkb:Q96N66 intact:EBI-12549378|ensembl:ENSP00000472769|uniprotkb:Q7L5R2|uniprotkb:Q9BPY7 intact:EBI-6116499|ensembl:ENSP00000245615|ensembl:ENSP00000478041|ensembl:ENSP00000478088|ensembl:ENSP00000478965|ensembl:ENSP00000481455|ensembl:ENSP00000482252|ensembl:ENSP00000482625|ensembl:ENSP00000484199|ensembl:ENSP00000484933|ensembl:ENSP00000484954|uniprotkb:A9C4B6|uniprotkb:B0V3I5|uniprotkb:B4DQ87|uniprotkb:Q05DF0|uniprotkb:Q7L5N2|uniprotkb:Q99908|uniprotkb:Q9BPV2|uniprotkb:Q9BRE9 psi-mi:tx101_human(display_long)|uniprotkb:TEX101(gene name)|psi-mi:TEX101(display_short)|uniprotkb:Cell surface receptor NYD-SP8(gene name synonym)|uniprotkb:SGRG(gene name synonym)|uniprotkb:Scleroderma-associated autoantigen(gene name synonym)|uniprotkb:Spermatogenesis-related gene protein(gene name synonym)|uniprotkb:UNQ867/PRO1884(orf name) psi-mi:mboa7_human(display_long)|uniprotkb:MBOAT7(gene name)|psi-mi:MBOAT7(display_short)|uniprotkb:BB1(gene name synonym)|uniprotkb:LENG4(gene name synonym)|uniprotkb:OACT7(gene name synonym)|uniprotkb:1-acylglycerophosphatidylinositol O-acyltransferase(gene name synonym)|uniprotkb:Bladder and breast carcinoma-overexpressed gene 1 protein(gene name synonym)|uniprotkb:Leukocyte receptor cluster member 4(gene name synonym)|uniprotkb:Lysophosphatidylinositol acyltransferase(gene name synonym)|uniprotkb:Membrane-bound O-acyltransferase domain-containing protein 7(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Schiza et al. (2018) imex:IM-28077|pubmed:30097533 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-25505061|imex:IM-28077-3 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000131126(gene)|ensembl:ENST00000598265(transcript)|go:"GO:0001669"(acrosomal vesicle)|go:"GO:0002080"(acrosomal membrane)|go:"GO:0005576"(extracellular region)|go:"GO:0005886"(plasma membrane)|go:"GO:0007339"(binding of sperm to zona pellucida)|go:"GO:0009566"(fertilization)|go:"GO:0030317"(flagellated sperm motility)|go:"GO:0044853"(plasma membrane raft)|go:"GO:0046658"(anchored component of plasma membrane)|go:"GO:1901317"(regulation of flagellated sperm motility)|interpro:IPR016054(Ly-6 antigen / uPA receptor -like)|rcsb pdb:7BPR|reactome:R-HSA-163125|refseq:NP_001123483.1|refseq:NP_113639.4 refseq:XP_011525601.1|refseq:XP_011525602.1|ensembl:ENSG00000125505(gene)|ensembl:ENSG00000273592(gene)|ensembl:ENSG00000274194(gene)|ensembl:ENSG00000275118(gene)|ensembl:ENSG00000276935(gene)|ensembl:ENSG00000277025(gene)|ensembl:ENSG00000277733(gene)|ensembl:ENSG00000277923(gene)|ensembl:ENSG00000278322(gene)|ensembl:ENSG00000278519(gene)|refseq:NP_001139528.1|refseq:NP_001139554.1|refseq:NP_001139555.1|refseq:NP_077274.3|ensembl:ENST00000245615(transcript)|ensembl:ENST00000613506(transcript)|ensembl:ENST00000613746(transcript)|ensembl:ENST00000615453(transcript)|ensembl:ENST00000617012(transcript)|ensembl:ENST00000618378(transcript)|ensembl:ENST00000619842(transcript)|ensembl:ENST00000619855(transcript)|ensembl:ENST00000621612(transcript)|ensembl:ENST00000621875(transcript)|go:"GO:0003841"(1-acylglycerol-3-phosphate O-acyltransferase activity)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006661"(phosphatidylinositol biosynthetic process)|go:"GO:0008374"(O-acyltransferase activity)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016746"(acyltransferase activity)|go:"GO:0021591"(ventricular system development)|go:"GO:0021819"(layer formation in cerebral cortex)|go:"GO:0030258"(lipid modification)|go:"GO:0036149"(phosphatidylinositol acyl-chain remodeling)|go:"GO:0036151"(phosphatidylcholine acyl-chain remodeling)|go:"GO:0044233"(mitochondria-associated endoplasmic reticulum membrane)|go:"GO:0047144"(2-acylglycerol-3-phosphate O-acyltransferase activity)|go:"GO:0071617"(lysophospholipid acyltransferase activity)|go:"GO:0090207"(regulation of triglyceride metabolic process)|interpro:IPR004299(Membrane bound O-acyl transferase, MBOAT)|mint:Q96N66|reactome:R-HSA-1482922 - - - figure legend:Fig.2A,Supp Table S5|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-testis)|taxid:9606(Homo sapiens) - 2020/03/24 2021/11/30 rogid:ZE4tXTFi7lUCcIbCL4KHzY3a6xM9606 rogid:NdxbWV63CtA/flzPPhYadlBQksU9606 rigid:/AFat0DrynAJ5ofEnoPSTThlxCE false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9BY14 uniprotkb:Q9P2R7 intact:EBI-12549378|ensembl:ENSP00000472769|uniprotkb:Q7L5R2|uniprotkb:Q9BPY7 intact:EBI-2269898|uniprotkb:O95194|uniprotkb:Q5T9Q4|uniprotkb:Q5T9Q6|uniprotkb:Q9NV21|uniprotkb:Q9NVP7|uniprotkb:B2RDE7|ensembl:ENSP00000494360|ensembl:ENSP00000494987 psi-mi:tx101_human(display_long)|uniprotkb:TEX101(gene name)|psi-mi:TEX101(display_short)|uniprotkb:Cell surface receptor NYD-SP8(gene name synonym)|uniprotkb:SGRG(gene name synonym)|uniprotkb:Scleroderma-associated autoantigen(gene name synonym)|uniprotkb:Spermatogenesis-related gene protein(gene name synonym)|uniprotkb:UNQ867/PRO1884(orf name) psi-mi:sucb1_human(display_long)|uniprotkb:SUCLA2(gene name)|psi-mi:SUCLA2(display_short)|uniprotkb:ATP-specific succinyl-CoA synthetase subunit beta(gene name synonym)|uniprotkb:Succinyl-CoA synthetase beta-A chain(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Schiza et al. (2018) imex:IM-28077|pubmed:30097533 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-25505061|imex:IM-28077-3 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000131126(gene)|ensembl:ENST00000598265(transcript)|go:"GO:0001669"(acrosomal vesicle)|go:"GO:0002080"(acrosomal membrane)|go:"GO:0005576"(extracellular region)|go:"GO:0005886"(plasma membrane)|go:"GO:0007339"(binding of sperm to zona pellucida)|go:"GO:0009566"(fertilization)|go:"GO:0030317"(flagellated sperm motility)|go:"GO:0044853"(plasma membrane raft)|go:"GO:0046658"(anchored component of plasma membrane)|go:"GO:1901317"(regulation of flagellated sperm motility)|interpro:IPR016054(Ly-6 antigen / uPA receptor -like)|rcsb pdb:7BPR|reactome:R-HSA-163125|refseq:NP_001123483.1|refseq:NP_113639.4 refseq:NP_003841.1|ensembl:ENSG00000136143(gene)|ensembl:ENST00000643584(transcript)|ensembl:ENST00000646932(transcript)|go:"GO:0000287"(magnesium ion binding)|go:"GO:0004775"("succinate-CoA ligase (ADP-forming) activity")|go:"GO:0004776"("succinate-CoA ligase (GDP-forming) activity")|go:"GO:0005524"(ATP binding)|go:"GO:0005739"(mitochondrion)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0006099"(tricarboxylic acid cycle)|go:"GO:0006104"(succinyl-CoA metabolic process)|go:"GO:0006105"(succinate metabolic process)|go:"GO:0006781"(succinyl-CoA pathway)|go:"GO:0042709"(succinate-CoA ligase complex)|go:"GO:0070062"(extracellular exosome)|interpro:IPR005809(Succinyl-CoA synthetase, beta subunit)|interpro:IPR005811(ATP-citrate lyase/succinyl-CoA ligase)|interpro:IPR011761(ATP-grasp fold)|interpro:IPR013650(ATP-grasp fold, succinyl-CoA synthetase-type)|interpro:IPR013815(ATP-grasp fold, subdomain 1)|interpro:IPR016102(Succinyl-CoA synthetase-like)|interpro:IPR017866|interpro:IPR034723|mint:Q9P2R7|rcsb pdb:6G4Q|reactome:R-HSA-71403 - - - figure legend:Fig.2A,Supp Table S5|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-testis)|taxid:9606(Homo sapiens) - 2020/03/24 2021/11/30 rogid:ZE4tXTFi7lUCcIbCL4KHzY3a6xM9606 rogid:I/FQp3c8ckxpxoyftKge2B5lDmI9606 rigid:/AFat0DrynAJ5ofEnoPSTThlxCE false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9BY14 uniprotkb:P12235 intact:EBI-12549378|ensembl:ENSP00000472769|uniprotkb:Q7L5R2|uniprotkb:Q9BPY7 intact:EBI-359074|uniprotkb:D3DP59|ensembl:ENSP00000281456 psi-mi:tx101_human(display_long)|uniprotkb:TEX101(gene name)|psi-mi:TEX101(display_short)|uniprotkb:Cell surface receptor NYD-SP8(gene name synonym)|uniprotkb:SGRG(gene name synonym)|uniprotkb:Scleroderma-associated autoantigen(gene name synonym)|uniprotkb:Spermatogenesis-related gene protein(gene name synonym)|uniprotkb:UNQ867/PRO1884(orf name) psi-mi:adt1_human(display_long)|uniprotkb:SLC25A4(gene name)|psi-mi:SLC25A4(display_short)|uniprotkb:ANT1(gene name synonym)|uniprotkb:Adenine nucleotide translocator 1(gene name synonym)|uniprotkb:ADP,ATP carrier protein 1(gene name synonym)|uniprotkb:Solute carrier family 25 member 4(gene name synonym)|uniprotkb:ADP,ATP carrier protein, heart/skeletal muscle isoform T1(gene name synonym)|uniprotkb:AAC1(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Schiza et al. (2018) imex:IM-28077|pubmed:30097533 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-25505061|imex:IM-28077-3 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000131126(gene)|ensembl:ENST00000598265(transcript)|go:"GO:0001669"(acrosomal vesicle)|go:"GO:0002080"(acrosomal membrane)|go:"GO:0005576"(extracellular region)|go:"GO:0005886"(plasma membrane)|go:"GO:0007339"(binding of sperm to zona pellucida)|go:"GO:0009566"(fertilization)|go:"GO:0030317"(flagellated sperm motility)|go:"GO:0044853"(plasma membrane raft)|go:"GO:0046658"(anchored component of plasma membrane)|go:"GO:1901317"(regulation of flagellated sperm motility)|interpro:IPR016054(Ly-6 antigen / uPA receptor -like)|rcsb pdb:7BPR|reactome:R-HSA-163125|refseq:NP_001123483.1|refseq:NP_113639.4 refseq:NP_001142.2|ensembl:ENST00000281456(transcript)|go:"GO:0000002"(mitochondrial genome maintenance)|go:"GO:0005471"("ATP:ADP antiporter activity")|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005757"(mitochondrial permeability transition pore complex)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006091"(generation of precursor metabolites and energy)|go:"GO:0008637"(apoptotic mitochondrial changes)|go:"GO:0015078"(proton transmembrane transporter activity)|go:"GO:0015207"(adenine transmembrane transporter activity)|go:"GO:0015866"(ADP transport)|ensembl:ENSG00000151729(gene)|go:"GO:0016020"(membrane)|go:"GO:0017077"(oxidative phosphorylation uncoupler activity)|go:"GO:0032592"(integral component of mitochondrial membrane)|go:"GO:0046902"(regulation of mitochondrial membrane permeability)|go:"GO:0060546"(negative regulation of necroptotic process)|go:"GO:0140021"(mitochondrial ADP transmembrane transport)|go:"GO:1901526"(positive regulation of mitophagy)|go:"GO:1990544"(mitochondrial ATP transmembrane transport)|go:"GO:1990845"(adaptive thermogenesis)|interpro:IPR002067(Mitochondrial carrier protein)|interpro:IPR002113(Adenine nucleotide translocator 1)|interpro:IPR018108|interpro:IPR023395|mint:P12235|reactome:R-HSA-1268020|reactome:R-HSA-180897|reactome:R-HSA-83936|dip:DIP-33116N - - - figure legend:Fig.2A,Supp Table S5|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-testis)|taxid:9606(Homo sapiens) - 2020/03/24 2021/11/30 rogid:ZE4tXTFi7lUCcIbCL4KHzY3a6xM9606 rogid:vs4XIUUUypcIHR9Lz4j1buDAnjM9606 rigid:/AFat0DrynAJ5ofEnoPSTThlxCE false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9BY14 uniprotkb:O43169 intact:EBI-12549378|ensembl:ENSP00000472769|uniprotkb:Q7L5R2|uniprotkb:Q9BPY7 intact:EBI-1058710|ensembl:ENSP00000308430|uniprotkb:A8K6B1|uniprotkb:Q96CC3|uniprotkb:Q9BT35|uniprotkb:J3KNF8 psi-mi:tx101_human(display_long)|uniprotkb:TEX101(gene name)|psi-mi:TEX101(display_short)|uniprotkb:Cell surface receptor NYD-SP8(gene name synonym)|uniprotkb:SGRG(gene name synonym)|uniprotkb:Scleroderma-associated autoantigen(gene name synonym)|uniprotkb:Spermatogenesis-related gene protein(gene name synonym)|uniprotkb:UNQ867/PRO1884(orf name) psi-mi:cyb5b_human(display_long)|uniprotkb:CYB5B(gene name)|psi-mi:CYB5B(display_short)|uniprotkb:CYB5M(gene name synonym)|uniprotkb:OMB5(gene name synonym)|uniprotkb:Cytochrome b5 outer mitochondrial membrane isoform(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Schiza et al. (2018) imex:IM-28077|pubmed:30097533 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-25505061|imex:IM-28077-3 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000131126(gene)|ensembl:ENST00000598265(transcript)|go:"GO:0001669"(acrosomal vesicle)|go:"GO:0002080"(acrosomal membrane)|go:"GO:0005576"(extracellular region)|go:"GO:0005886"(plasma membrane)|go:"GO:0007339"(binding of sperm to zona pellucida)|go:"GO:0009566"(fertilization)|go:"GO:0030317"(flagellated sperm motility)|go:"GO:0044853"(plasma membrane raft)|go:"GO:0046658"(anchored component of plasma membrane)|go:"GO:1901317"(regulation of flagellated sperm motility)|interpro:IPR016054(Ly-6 antigen / uPA receptor -like)|rcsb pdb:7BPR|reactome:R-HSA-163125|refseq:NP_001123483.1|refseq:NP_113639.4 ensembl:ENSG00000103018(gene)|ensembl:ENST00000307892(transcript)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0006805"(xenobiotic metabolic process)|go:"GO:0006809"(nitric oxide biosynthetic process)|go:"GO:0006979"(response to oxidative stress)|go:"GO:0008047"(enzyme activator activity)|go:"GO:0009055"(electron transfer activity)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0020037"(heme binding)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0046872"(metal ion binding)|go:"GO:1903958"(nitric-oxide synthase complex)|interpro:IPR001199(Cytochrome b5)|interpro:IPR018506|interpro:IPR036400|rcsb pdb:3NER|reactome:R-HSA-211945|refseq:NP_085056.2 - - - figure legend:Fig.2A,Supp Table S5|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-testis)|taxid:9606(Homo sapiens) - 2020/03/24 2021/11/30 rogid:ZE4tXTFi7lUCcIbCL4KHzY3a6xM9606 rogid:EggIdVT68dznAuzk5wDa3H7mV2c9606 rigid:/AFat0DrynAJ5ofEnoPSTThlxCE false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9BY14 uniprotkb:Q12907 intact:EBI-12549378|ensembl:ENSP00000472769|uniprotkb:Q7L5R2|uniprotkb:Q9BPY7 intact:EBI-3915406|uniprotkb:Q53HH1|ensembl:ENSP00000303366 psi-mi:tx101_human(display_long)|uniprotkb:TEX101(gene name)|psi-mi:TEX101(display_short)|uniprotkb:Cell surface receptor NYD-SP8(gene name synonym)|uniprotkb:SGRG(gene name synonym)|uniprotkb:Scleroderma-associated autoantigen(gene name synonym)|uniprotkb:Spermatogenesis-related gene protein(gene name synonym)|uniprotkb:UNQ867/PRO1884(orf name) psi-mi:lman2_human(display_long)|uniprotkb:LMAN2(gene name)|psi-mi:LMAN2(display_short)|uniprotkb:C5orf8(gene name synonym)|uniprotkb:Glycoprotein GP36b(gene name synonym)|uniprotkb:Lectin mannose-binding 2(gene name synonym)|uniprotkb:Vesicular integral-membrane protein 36(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Schiza et al. (2018) imex:IM-28077|pubmed:30097533 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-25505061|imex:IM-28077-3 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000131126(gene)|ensembl:ENST00000598265(transcript)|go:"GO:0001669"(acrosomal vesicle)|go:"GO:0002080"(acrosomal membrane)|go:"GO:0005576"(extracellular region)|go:"GO:0005886"(plasma membrane)|go:"GO:0007339"(binding of sperm to zona pellucida)|go:"GO:0009566"(fertilization)|go:"GO:0030317"(flagellated sperm motility)|go:"GO:0044853"(plasma membrane raft)|go:"GO:0046658"(anchored component of plasma membrane)|go:"GO:1901317"(regulation of flagellated sperm motility)|interpro:IPR016054(Ly-6 antigen / uPA receptor -like)|rcsb pdb:7BPR|reactome:R-HSA-163125|refseq:NP_001123483.1|refseq:NP_113639.4 refseq:NP_006807.1|ensembl:ENSG00000169223(gene)|ensembl:ENST00000303127(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0005537"(mannose binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005793"(endoplasmic reticulum-Golgi intermediate compartment)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0006890"(retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum)|go:"GO:0007029"(endoplasmic reticulum organization)|go:"GO:0007030"(Golgi organization)|go:"GO:0009986"(cell surface)|go:"GO:0015031"(protein transport)|go:"GO:0030134"(COPII-coated ER to Golgi transport vesicle)|go:"GO:0030246"(carbohydrate binding)|go:"GO:0031072"(heat shock protein binding)|go:"GO:0033116"(endoplasmic reticulum-Golgi intermediate compartment membrane)|go:"GO:0046872"(metal ion binding)|go:"GO:0050766"(positive regulation of phagocytosis)|go:"GO:0070062"(extracellular exosome)|interpro:IPR005052(Legume-like lectin)|interpro:IPR013320(Concanavalin A-like lectin/glucanase, subgroup)|interpro:IPR035664|mint:Q12907|reactome:R-HSA-204005|reactome:R-HSA-5694530 - - - figure legend:Fig.2A,Supp Table S5|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-testis)|taxid:9606(Homo sapiens) - 2020/03/24 2021/11/30 rogid:ZE4tXTFi7lUCcIbCL4KHzY3a6xM9606 rogid:goqUZGW9/lvVMWDAZS9csH3TqWY9606 rigid:/AFat0DrynAJ5ofEnoPSTThlxCE false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9BY14 uniprotkb:P21926 intact:EBI-12549378|ensembl:ENSP00000472769|uniprotkb:Q7L5R2|uniprotkb:Q9BPY7 intact:EBI-4280101|uniprotkb:D3DUQ9|uniprotkb:Q5J7W6|uniprotkb:Q96ES4|ensembl:ENSP00000009180|ensembl:ENSP00000371958|ensembl:ENSP00000496639 psi-mi:tx101_human(display_long)|uniprotkb:TEX101(gene name)|psi-mi:TEX101(display_short)|uniprotkb:Cell surface receptor NYD-SP8(gene name synonym)|uniprotkb:SGRG(gene name synonym)|uniprotkb:Scleroderma-associated autoantigen(gene name synonym)|uniprotkb:Spermatogenesis-related gene protein(gene name synonym)|uniprotkb:UNQ867/PRO1884(orf name) psi-mi:cd9_human(display_long)|uniprotkb:CD9(gene name)|psi-mi:CD9(display_short)|uniprotkb:MIC3(gene name synonym)|uniprotkb:TSPAN29(gene name synonym)|uniprotkb:5H9 antigen(gene name synonym)|uniprotkb:Cell growth-inhibiting gene 2 protein(gene name synonym)|uniprotkb:Leukocyte antigen MIC3(gene name synonym)|uniprotkb:Motility-related protein(gene name synonym)|uniprotkb:Tetraspanin-29(gene name synonym)|uniprotkb:p24(gene name synonym)|uniprotkb:GIG2(orf name) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Schiza et al. (2018) imex:IM-28077|pubmed:30097533 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-25505061|imex:IM-28077-3 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000131126(gene)|ensembl:ENST00000598265(transcript)|go:"GO:0001669"(acrosomal vesicle)|go:"GO:0002080"(acrosomal membrane)|go:"GO:0005576"(extracellular region)|go:"GO:0005886"(plasma membrane)|go:"GO:0007339"(binding of sperm to zona pellucida)|go:"GO:0009566"(fertilization)|go:"GO:0030317"(flagellated sperm motility)|go:"GO:0044853"(plasma membrane raft)|go:"GO:0046658"(anchored component of plasma membrane)|go:"GO:1901317"(regulation of flagellated sperm motility)|interpro:IPR016054(Ly-6 antigen / uPA receptor -like)|rcsb pdb:7BPR|reactome:R-HSA-163125|refseq:NP_001123483.1|refseq:NP_113639.4 refseq:NP_001760.1|ensembl:ENSG00000010278(gene)|ensembl:ENST00000009180(transcript)|ensembl:ENST00000382518(transcript)|ensembl:ENST00000538834(transcript)|go:"GO:0005178"(integrin binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0005925"(focal adhesion)|go:"GO:0007155"(cell adhesion)|go:"GO:0007342"(fusion of sperm to egg plasma membrane involved in single fertilization)|go:"GO:0007420"(brain development)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0008347"(glial cell migration)|go:"GO:0009414"(response to water deprivation)|go:"GO:0009897"(external side of plasma membrane)|go:"GO:0014003"(oligodendrocyte development)|go:"GO:0014905"(myoblast fusion involved in skeletal muscle regeneration)|go:"GO:0016020"(membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0030168"(platelet activation)|go:"GO:0030666"(endocytic vesicle membrane)|go:"GO:0030669"(clathrin-coated endocytic vesicle membrane)|go:"GO:0030913"(paranodal junction assembly)|go:"GO:0031092"(platelet alpha granule membrane)|go:"GO:0031623"(receptor internalization)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035036"(sperm-egg recognition)|go:"GO:0051271"(negative regulation of cellular component movement)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071404"(cellular response to low-density lipoprotein particle stimulus)|go:"GO:0090331"(negative regulation of platelet aggregation)|go:"GO:1903561"(extracellular vesicle)|go:"GO:1905521"(regulation of macrophage migration)|interpro:IPR000301(CD9/CD37/CD63 antigen)|interpro:IPR008952(Tetraspanin)|interpro:IPR018499|interpro:IPR018503|interpro:IPR042055|rcsb pdb:6K4J|rcsb pdb:6RLO|rcsb pdb:6RLR|rcsb pdb:6Z1V|rcsb pdb:6Z20|reactome:R-HSA-114608|reactome:R-HSA-1300645|reactome:R-HSA-5336415|refseq:NP_001317241.1|dip:DIP-1122N - - - figure legend:Fig.2A,Supp Table S5|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-testis)|taxid:9606(Homo sapiens) - 2020/03/24 2021/11/30 rogid:ZE4tXTFi7lUCcIbCL4KHzY3a6xM9606 rogid:3IurQcWENxQVeRwGfqL0Os8m81E9606 rigid:/AFat0DrynAJ5ofEnoPSTThlxCE false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9BY14 uniprotkb:P21796 intact:EBI-12549378|ensembl:ENSP00000472769|uniprotkb:Q7L5R2|uniprotkb:Q9BPY7 intact:EBI-354158|uniprotkb:Q5FVE7|uniprotkb:Q9UIQ5|uniprotkb:Q9UPL0|uniprotkb:B3KVK4|uniprotkb:D3DQ93|ensembl:ENSP00000265333|ensembl:ENSP00000378484|ensembl:ENSP00000378487 psi-mi:tx101_human(display_long)|uniprotkb:TEX101(gene name)|psi-mi:TEX101(display_short)|uniprotkb:Cell surface receptor NYD-SP8(gene name synonym)|uniprotkb:SGRG(gene name synonym)|uniprotkb:Scleroderma-associated autoantigen(gene name synonym)|uniprotkb:Spermatogenesis-related gene protein(gene name synonym)|uniprotkb:UNQ867/PRO1884(orf name) psi-mi:vdac1_human(display_long)|uniprotkb:VDAC1(gene name)|psi-mi:VDAC1(display_short)|uniprotkb:VDAC(gene name synonym)|uniprotkb:Outer mitochondrial membrane protein porin 1(gene name synonym)|uniprotkb:Plasmalemmal porin(gene name synonym)|uniprotkb:Porin 31HL(gene name synonym)|uniprotkb:Porin 31HM(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Schiza et al. (2018) imex:IM-28077|pubmed:30097533 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-25505061|imex:IM-28077-3 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000131126(gene)|ensembl:ENST00000598265(transcript)|go:"GO:0001669"(acrosomal vesicle)|go:"GO:0002080"(acrosomal membrane)|go:"GO:0005576"(extracellular region)|go:"GO:0005886"(plasma membrane)|go:"GO:0007339"(binding of sperm to zona pellucida)|go:"GO:0009566"(fertilization)|go:"GO:0030317"(flagellated sperm motility)|go:"GO:0044853"(plasma membrane raft)|go:"GO:0046658"(anchored component of plasma membrane)|go:"GO:1901317"(regulation of flagellated sperm motility)|interpro:IPR016054(Ly-6 antigen / uPA receptor -like)|rcsb pdb:7BPR|reactome:R-HSA-163125|refseq:NP_001123483.1|refseq:NP_113639.4 refseq:NP_003365.1|refseq:XP_005272132.1|refseq:XP_016865310.1|refseq:XP_016865311.1|refseq:XP_016865312.1|dip:DIP-32862N|ensembl:ENSG00000213585(gene)|ensembl:ENST00000265333(transcript)|ensembl:ENST00000395044(transcript)|ensembl:ENST00000395047(transcript)|go:"GO:0001662"(behavioral fear response)|go:"GO:0005634"(nucleus)|go:"GO:0005739"(mitochondrion)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005757"(mitochondrial permeability transition pore complex)|go:"GO:0005886"(plasma membrane)|go:"GO:0006090"(pyruvate metabolic process)|go:"GO:0006820"(anion transport)|go:"GO:0006851"(mitochondrial calcium ion transmembrane transport)|go:"GO:0006915"(apoptotic process)|go:"GO:0007270"(neuron-neuron synaptic transmission)|go:"GO:0007612"(learning)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0008308"(voltage-gated anion channel activity)|go:"GO:0015288"(porin activity)|go:"GO:0015485"(cholesterol binding)|go:"GO:0016020"(membrane)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030855"(epithelial cell differentiation)|go:"GO:0031210"(phosphatidylcholine binding)|go:"GO:0031966"(mitochondrial membrane)|go:"GO:0042645"(mitochondrial nucleoid)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045121"(membrane raft)|go:"GO:0046930"(pore complex)|go:"GO:0070062"(extracellular exosome)|go:"GO:0097001"(ceramide binding)|go:"GO:0110099"(negative regulation of calcium import into the mitochondrion)|go:"GO:1901526"(positive regulation of mitophagy)|go:"GO:1903146"(regulation of autophagy of mitochondrion)|go:"GO:2000378"(negative regulation of reactive oxygen species metabolic process)|interpro:IPR001925(Porin, eukaryotic type)|interpro:IPR023614|interpro:IPR027246|interpro:IPR030270|mint:P21796|rcsb pdb:2JK4|rcsb pdb:2K4T|rcsb pdb:5JDP|rcsb pdb:5XDN|rcsb pdb:5XDO|rcsb pdb:6G6U|rcsb pdb:6G73|rcsb pdb:6TIQ|rcsb pdb:6TIR|reactome:R-HSA-1268020|reactome:R-HSA-5205685|reactome:R-HSA-5689880|reactome:R-HSA-70268|reactome:R-HSA-8949215 - - - figure legend:Fig.2A,Supp Table S5|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-testis)|taxid:9606(Homo sapiens) - 2020/03/24 2021/11/30 rogid:ZE4tXTFi7lUCcIbCL4KHzY3a6xM9606 rogid:8Fqe6Ga3NmwwuICa4L45ga2i1nk9606 rigid:/AFat0DrynAJ5ofEnoPSTThlxCE false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9BY14 uniprotkb:P05556 intact:EBI-12549378|ensembl:ENSP00000472769|uniprotkb:Q7L5R2|uniprotkb:Q9BPY7 intact:EBI-703066|intact:EBI-4289597|ensembl:ENSP00000303351|ensembl:ENSP00000379350|ensembl:ENSP00000398029|ensembl:ENSP00000404546|ensembl:ENSP00000502882|ensembl:ENSP00000503546|ensembl:ENSP00000503916|ensembl:ENSP00000504205|ensembl:ENSP00000504444|uniprotkb:Q7Z3V1|uniprotkb:Q8WUM6|uniprotkb:P78466|uniprotkb:P78467|uniprotkb:Q13089|uniprotkb:Q13090|uniprotkb:Q13091|uniprotkb:Q13212|uniprotkb:Q14622|uniprotkb:Q14647|uniprotkb:A8K6N2|uniprotkb:Q29RW2|uniprotkb:D3DRX9|uniprotkb:D3DRY3|uniprotkb:D3DRY4|uniprotkb:D3DRY5 psi-mi:tx101_human(display_long)|uniprotkb:TEX101(gene name)|psi-mi:TEX101(display_short)|uniprotkb:Cell surface receptor NYD-SP8(gene name synonym)|uniprotkb:SGRG(gene name synonym)|uniprotkb:Scleroderma-associated autoantigen(gene name synonym)|uniprotkb:Spermatogenesis-related gene protein(gene name synonym)|uniprotkb:UNQ867/PRO1884(orf name) psi-mi:itb1_human(display_long)|uniprotkb:Fibronectin receptor subunit beta(gene name synonym)|uniprotkb:VLA-4 subunit beta(gene name synonym)|uniprotkb:ITGB1(gene name)|psi-mi:ITGB1(display_short)|uniprotkb:FNRB(gene name synonym)|uniprotkb:MDF2(gene name synonym)|uniprotkb:MSK12(gene name synonym)|uniprotkb:Glycoprotein IIa(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Schiza et al. (2018) imex:IM-28077|pubmed:30097533 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-25505061|imex:IM-28077-3 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000131126(gene)|ensembl:ENST00000598265(transcript)|go:"GO:0001669"(acrosomal vesicle)|go:"GO:0002080"(acrosomal membrane)|go:"GO:0005576"(extracellular region)|go:"GO:0005886"(plasma membrane)|go:"GO:0007339"(binding of sperm to zona pellucida)|go:"GO:0009566"(fertilization)|go:"GO:0030317"(flagellated sperm motility)|go:"GO:0044853"(plasma membrane raft)|go:"GO:0046658"(anchored component of plasma membrane)|go:"GO:1901317"(regulation of flagellated sperm motility)|interpro:IPR016054(Ly-6 antigen / uPA receptor -like)|rcsb pdb:7BPR|reactome:R-HSA-163125|refseq:NP_001123483.1|refseq:NP_113639.4 go:"GO:0001618"(virus receptor activity)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0001708"(cell fate specification)|go:"GO:0001726"(ruffle)|go:"GO:0001968"(fibronectin binding)|go:"GO:0002020"(protease binding)|go:"GO:0002042"(cell migration involved in sprouting angiogenesis)|go:"GO:0003779"(actin binding)|go:"GO:0005178"(integrin binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0005925"(focal adhesion)|go:"GO:0006909"(phagocytosis)|go:"GO:0006968"(cellular defense response)|go:"GO:0007155"(cell adhesion)|go:"GO:0007156"(homophilic cell adhesion via plasma membrane adhesion molecules)|go:"GO:0007159"(leukocyte cell-cell adhesion)|go:"GO:0007160"(cell-matrix adhesion)|go:"GO:0007161"(calcium-independent cell-matrix adhesion)|go:"GO:0007229"(integrin-mediated signaling pathway)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0008354"(germ cell migration)|go:"GO:0008542"(visual learning)|go:"GO:0009897"(external side of plasma membrane)|go:"GO:0009986"(cell surface)|go:"GO:0010008"(endosome membrane)|go:"GO:0010710"(regulation of collagen catabolic process)|go:"GO:0010763"(positive regulation of fibroblast migration)|go:"GO:0014704"(intercalated disc)|go:"GO:0015026"(coreceptor activity)|go:"GO:0016020"(membrane)|go:"GO:0016477"(cell migration)|go:"GO:0021943"(formation of radial glial scaffolds)|go:"GO:0023035"(CD40 signaling pathway)|go:"GO:0030027"(lamellipodium)|go:"GO:0030030"(cell projection organization)|go:"GO:0030032"(lamellipodium assembly)|go:"GO:0030175"(filopodium)|go:"GO:0030183"(B cell differentiation)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0031589"(cell-substrate adhesion)|go:"GO:0031594"(neuromuscular junction)|go:"GO:0031623"(receptor internalization)|go:"GO:0032154"(cleavage furrow)|go:"GO:0032587"(ruffle membrane)|go:"GO:0033627"(cell adhesion mediated by integrin)|go:"GO:0033631"(cell-cell adhesion mediated by integrin)|go:"GO:0034113"(heterotypic cell-cell adhesion)|go:"GO:0034665"(integrin alpha1-beta1 complex)|go:"GO:0034666"(integrin alpha2-beta1 complex)|go:"GO:0034667"(integrin alpha3-beta1 complex)|go:"GO:0034668"(integrin alpha4-beta1 complex)|go:"GO:0034674"(integrin alpha5-beta1 complex)|go:"GO:0034677"(integrin alpha7-beta1 complex)|go:"GO:0034678"(integrin alpha8-beta1 complex)|go:"GO:0034680"(integrin alpha10-beta1 complex)|go:"GO:0034681"(integrin alpha11-beta1 complex)|go:"GO:0035024"(negative regulation of Rho protein signal transduction)|go:"GO:0035633"(maintenance of blood-brain barrier)|go:"GO:0035748"(myelin sheath abaxonal region)|go:"GO:0042383"(sarcolemma)|go:"GO:0042470"(melanosome)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043197"(dendritic spine)|go:"GO:0043235"(receptor complex)|go:"GO:0043236"(laminin binding)|go:"GO:0043547"(positive regulation of GTPase activity)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045121"(membrane raft)|go:"GO:0045214"(sarcomere organization)|go:"GO:0045296"(cadherin binding)|go:"GO:0045596"(negative regulation of cell differentiation)|go:"GO:0045766"(positive regulation of angiogenesis)|go:"GO:0046872"(metal ion binding)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0048333"(mesodermal cell differentiation)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0048675"(axon extension)|go:"GO:0048813"(dendrite morphogenesis)|go:"GO:0050839"(cell adhesion molecule binding)|go:"GO:0050901"(leukocyte tethering or rolling)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0051897"(positive regulation of protein kinase B signaling)|go:"GO:0051951"(positive regulation of glutamate uptake involved in transmission of nerve impulse)|go:"GO:0055007"(cardiac muscle cell differentiation)|go:"GO:0055037"(recycling endosome)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071404"(cellular response to low-density lipoprotein particle stimulus)|go:"GO:0071711"(basement membrane organization)|go:"GO:0090303"(positive regulation of wound healing)|go:"GO:0097386"(glial cell projection)|go:"GO:0098639"(collagen binding involved in cell-matrix adhesion)|go:"GO:0098685"(Schaffer collateral - CA1 synapse)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099699"(integral component of synaptic membrane)|go:"GO:0150003"(regulation of spontaneous synaptic transmission)|go:"GO:0150103"(reactive gliosis)|go:"GO:1901979"(regulation of inward rectifier potassium channel activity)|go:"GO:1903078"(positive regulation of protein localization to plasma membrane)|go:"GO:1990782"(protein tyrosine kinase binding)|go:"GO:2000273"(positive regulation of signaling receptor activity)|go:"GO:2000811"(negative regulation of anoikis)|interpro:IPR002369(Integrin beta subunit, N-terminal)|interpro:IPR012896(Integrin beta subunit, tail)|interpro:IPR013111(EGF, extracellular)|interpro:IPR014836(Integrin beta subunit, cytoplasmic)|interpro:IPR015812(Integrin beta subunit)|interpro:IPR016201(Plexin-like fold)|interpro:IPR027071|interpro:IPR032695|interpro:IPR033760|interpro:IPR036349|interpro:IPR036465|interpro:IPR040622|mint:P05556|rcsb pdb:1K11|rcsb pdb:1LHA|rcsb pdb:3G9W|rcsb pdb:3T9K|rcsb pdb:3VI3|rcsb pdb:3VI4|rcsb pdb:4DX9|rcsb pdb:4WJK|rcsb pdb:4WK0|rcsb pdb:4WK2|rcsb pdb:4WK4|rcsb pdb:7CEB|rcsb pdb:7CEC|rcsb pdb:7NWL|reactome:R-HSA-1566948|reactome:R-HSA-1566977|reactome:R-HSA-198933|ensembl:ENSG00000150093(gene)|ensembl:ENST00000302278(transcript)|ensembl:ENST00000396033(transcript)|ensembl:ENST00000417122(transcript)|ensembl:ENST00000437302(transcript)|ensembl:ENST00000677999(transcript)|ensembl:ENST00000678701(transcript)|ensembl:ENST00000678943(transcript)|ensembl:ENST00000678952(transcript)|ensembl:ENST00000678989(transcript)|go:"GO:0000082"(G1/S transition of mitotic cell cycle)|go:"GO:0000132"(establishment of mitotic spindle orientation)|refseq:NP_002202.2|refseq:NP_391988.1|refseq:NP_596867.1|dip:DIP-312N|reactome:R-HSA-202733|reactome:R-HSA-210991|reactome:R-HSA-2129379|reactome:R-HSA-216083|reactome:R-HSA-3000157|reactome:R-HSA-3000170|reactome:R-HSA-3000178|reactome:R-HSA-416700|reactome:R-HSA-445144|reactome:R-HSA-446343|reactome:R-HSA-447041|reactome:R-HSA-5663220|reactome:R-HSA-6785807|reactome:R-HSA-75892|reactome:R-HSA-8874081|reactome:R-HSA-8875513|reactome:R-HSA-9013149|reactome:R-HSA-9013404|reactome:R-HSA-9013408|reactome:R-HSA-9013423|reactome:R-HSA-9609690|reactome:R-HSA-9679191 - - - figure legend:Fig.2A,Supp Table S5|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-testis)|taxid:9606(Homo sapiens) - 2020/03/24 2021/11/30 rogid:ZE4tXTFi7lUCcIbCL4KHzY3a6xM9606 rogid:FZ+lMRS6Zq07A8Lgmf5C6vEXUgM9606 rigid:/AFat0DrynAJ5ofEnoPSTThlxCE false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9BY14 uniprotkb:P02743 intact:EBI-12549378|ensembl:ENSP00000472769|uniprotkb:Q7L5R2|uniprotkb:Q9BPY7 intact:EBI-2115799|ensembl:ENSP00000255040 psi-mi:tx101_human(display_long)|uniprotkb:TEX101(gene name)|psi-mi:TEX101(display_short)|uniprotkb:Cell surface receptor NYD-SP8(gene name synonym)|uniprotkb:SGRG(gene name synonym)|uniprotkb:Scleroderma-associated autoantigen(gene name synonym)|uniprotkb:Spermatogenesis-related gene protein(gene name synonym)|uniprotkb:UNQ867/PRO1884(orf name) psi-mi:samp_human(display_long)|uniprotkb:APCS(gene name)|psi-mi:APCS(display_short)|uniprotkb:PTX2(gene name synonym)|uniprotkb:9.5S alpha-1-glycoprotein(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Schiza et al. (2018) imex:IM-28077|pubmed:30097533 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-25505061|imex:IM-28077-3 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000131126(gene)|ensembl:ENST00000598265(transcript)|go:"GO:0001669"(acrosomal vesicle)|go:"GO:0002080"(acrosomal membrane)|go:"GO:0005576"(extracellular region)|go:"GO:0005886"(plasma membrane)|go:"GO:0007339"(binding of sperm to zona pellucida)|go:"GO:0009566"(fertilization)|go:"GO:0030317"(flagellated sperm motility)|go:"GO:0044853"(plasma membrane raft)|go:"GO:0046658"(anchored component of plasma membrane)|go:"GO:1901317"(regulation of flagellated sperm motility)|interpro:IPR016054(Ly-6 antigen / uPA receptor -like)|rcsb pdb:7BPR|reactome:R-HSA-163125|refseq:NP_001123483.1|refseq:NP_113639.4 refseq:NP_001630.1|dip:DIP-46911N|ensembl:ENSG00000132703(gene)|ensembl:ENST00000255040(transcript)|go:"GO:0001849"(complement component C1q complex binding)|go:"GO:0002674"(negative regulation of acute inflammatory response)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0005634"(nucleus)|go:"GO:0006457"(protein folding)|go:"GO:0006953"(acute-phase response)|go:"GO:0006958"(complement activation, classical pathway)|go:"GO:0030169"(low-density lipoprotein particle binding)|go:"GO:0030246"(carbohydrate binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0044793"(negative regulation by host of viral process)|go:"GO:0044869"(negative regulation by host of viral exo-alpha-sialidase activity)|go:"GO:0044871"(negative regulation by host of viral glycoprotein metabolic process)|go:"GO:0045087"(innate immune response)|go:"GO:0045656"(negative regulation of monocyte differentiation)|go:"GO:0046597"(negative regulation of viral entry into host cell)|go:"GO:0046790"(virion binding)|go:"GO:0048525"(negative regulation of viral process)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0051131"(chaperone-mediated protein complex assembly)|go:"GO:0061045"(negative regulation of wound healing)|go:"GO:0062023"(collagen-containing extracellular matrix)|go:"GO:0070062"(extracellular exosome)|go:"GO:0072562"(blood microparticle)|go:"GO:1903016"(negative regulation of exo-alpha-sialidase activity)|go:"GO:1903019"(negative regulation of glycoprotein metabolic process)|interpro:IPR001759(Pentaxin)|interpro:IPR013320(Concanavalin A-like lectin/glucanase, subgroup)|interpro:IPR030476|rcsb pdb:1GYK|rcsb pdb:1LGN|rcsb pdb:1SAC|rcsb pdb:2A3W|rcsb pdb:2A3X|rcsb pdb:2A3Y|rcsb pdb:2W08|rcsb pdb:3D5O|rcsb pdb:3KQR|rcsb pdb:4AVS|rcsb pdb:4AVT|rcsb pdb:4AVV|rcsb pdb:4AYU|reactome:R-HSA-977225 - - - figure legend:Fig.2A,Supp Table S5|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-testis)|taxid:9606(Homo sapiens) - 2020/03/24 2021/11/30 rogid:ZE4tXTFi7lUCcIbCL4KHzY3a6xM9606 rogid:WOzyPFzTtaBN2E4vVhJyXLGNLcY9606 rigid:/AFat0DrynAJ5ofEnoPSTThlxCE false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9BY14 uniprotkb:P17813 intact:EBI-12549378|ensembl:ENSP00000472769|uniprotkb:Q7L5R2|uniprotkb:Q9BPY7 intact:EBI-2834630|uniprotkb:Q5T9C0|uniprotkb:Q14248|uniprotkb:Q14926|ensembl:ENSP00000362299 psi-mi:tx101_human(display_long)|uniprotkb:TEX101(gene name)|psi-mi:TEX101(display_short)|uniprotkb:Cell surface receptor NYD-SP8(gene name synonym)|uniprotkb:SGRG(gene name synonym)|uniprotkb:Scleroderma-associated autoantigen(gene name synonym)|uniprotkb:Spermatogenesis-related gene protein(gene name synonym)|uniprotkb:UNQ867/PRO1884(orf name) psi-mi:egln_human(display_long)|uniprotkb:ENG(gene name)|psi-mi:ENG(display_short)|uniprotkb:END(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Schiza et al. (2018) imex:IM-28077|pubmed:30097533 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-25505061|imex:IM-28077-3 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000131126(gene)|ensembl:ENST00000598265(transcript)|go:"GO:0001669"(acrosomal vesicle)|go:"GO:0002080"(acrosomal membrane)|go:"GO:0005576"(extracellular region)|go:"GO:0005886"(plasma membrane)|go:"GO:0007339"(binding of sperm to zona pellucida)|go:"GO:0009566"(fertilization)|go:"GO:0030317"(flagellated sperm motility)|go:"GO:0044853"(plasma membrane raft)|go:"GO:0046658"(anchored component of plasma membrane)|go:"GO:1901317"(regulation of flagellated sperm motility)|interpro:IPR016054(Ly-6 antigen / uPA receptor -like)|rcsb pdb:7BPR|reactome:R-HSA-163125|refseq:NP_001123483.1|refseq:NP_113639.4 go:"GO:0005615"(extracellular space)|go:"GO:0005886"(plasma membrane)|go:"GO:0005925"(focal adhesion)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0007155"(cell adhesion)|go:"GO:0007179"(transforming growth factor beta receptor signaling pathway)|go:"GO:0009897"(external side of plasma membrane)|go:"GO:0009986"(cell surface)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0010862"(positive regulation of pathway-restricted SMAD protein phosphorylation)|go:"GO:0015026"(coreceptor activity)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016477"(cell migration)|go:"GO:0016604"(nuclear body)|go:"GO:0017015"(regulation of transforming growth factor beta receptor signaling pathway)|go:"GO:0022009"(central nervous system vasculogenesis)|go:"GO:0022617"(extracellular matrix disassembly)|go:"GO:0030155"(regulation of cell adhesion)|go:"GO:0005539"(glycosaminoglycan binding)|go:"GO:0030336"(negative regulation of cell migration)|go:"GO:0030509"(BMP signaling pathway)|go:"GO:0030512"(negative regulation of transforming growth factor beta receptor signaling pathway)|go:"GO:0030513"(positive regulation of BMP signaling pathway)|go:"GO:0031953"(negative regulation of protein autophosphorylation)|go:"GO:0031960"(response to corticosteroid)|go:"GO:0032967"(positive regulation of collagen biosynthetic process)|go:"GO:0034713"(type I transforming growth factor beta receptor binding)|go:"GO:0035912"(dorsal aorta morphogenesis)|go:"GO:0042060"(wound healing)|go:"GO:0042127"(regulation of cell population proliferation)|go:"GO:0042325"(regulation of phosphorylation)|go:"GO:0042493"|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043235"(receptor complex)|go:"GO:0045766"(positive regulation of angiogenesis)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048185"(activin binding)|go:"GO:0048745"(smooth muscle tissue development)|go:"GO:0048844"(artery morphogenesis)|go:"GO:0048845"(venous blood vessel morphogenesis)|go:"GO:0048870"(cell motility)|go:"GO:0050431"(transforming growth factor beta binding)|go:"GO:0051001"(negative regulation of nitric-oxide synthase activity)|go:"GO:0051897"(positive regulation of protein kinase B signaling)|go:"GO:0055009"(atrial cardiac muscle tissue morphogenesis)|go:"GO:0060326"(cell chemotaxis)|go:"GO:0060348"(bone development)|go:"GO:0060394"(negative regulation of pathway-restricted SMAD protein phosphorylation)|go:"GO:0070278"(extracellular matrix constituent secretion)|go:"GO:0070483"(detection of hypoxia)|go:"GO:0071260"(cellular response to mechanical stimulus)|go:"GO:0072563"(endothelial microparticle)|go:"GO:0097084"(vascular associated smooth muscle cell development)|go:"GO:1905007"(positive regulation of epithelial to mesenchymal transition involved in endocardial cushion formation)|go:"GO:1905065"(positive regulation of vascular associated smooth muscle cell differentiation)|go:"GO:1905222"(atrioventricular canal morphogenesis)|interpro:IPR001507(Endoglin/CD105 antigen)|mint:P17813|rcsb pdb:5HZV|rcsb pdb:5HZW|rcsb pdb:5I04|ensembl:ENSG00000106991(gene)|ensembl:ENST00000373203(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0001525"(angiogenesis)|go:"GO:0001569"(branching involved in blood vessel morphogenesis)|go:"GO:0001666"(response to hypoxia)|go:"GO:0001837"(epithelial to mesenchymal transition)|go:"GO:0001934"(positive regulation of protein phosphorylation)|go:"GO:0001937"(negative regulation of endothelial cell proliferation)|go:"GO:0001947"(heart looping)|go:"GO:0003084"(positive regulation of systemic arterial blood pressure)|go:"GO:0003148"(outflow tract septum morphogenesis)|go:"GO:0003198"(epithelial to mesenchymal transition involved in endocardial cushion formation)|go:"GO:0003203"(endocardial cushion morphogenesis)|go:"GO:0003208"(cardiac ventricle morphogenesis)|go:"GO:0003209"(cardiac atrium morphogenesis)|go:"GO:0003222"(ventricular trabecula myocardium morphogenesis)|go:"GO:0003273"(cell migration involved in endocardial cushion formation)|go:"GO:0004888"(transmembrane signaling receptor activity)|go:"GO:0005024"(transforming growth factor beta-activated receptor activity)|go:"GO:0005114"(type II transforming growth factor beta receptor binding)|go:"GO:0005534"(galactose binding)|go:"GO:0001570"(vasculogenesis)|refseq:NP_000109.1|refseq:NP_001108225.1|refseq:NP_001265067.1|dip:DIP-6246N - - - figure legend:Fig.2A,Supp Table S5|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-testis)|taxid:9606(Homo sapiens) - 2020/03/24 2021/11/30 rogid:ZE4tXTFi7lUCcIbCL4KHzY3a6xM9606 rogid:6+7wUY8XztGVcjgbUlGaRjvBIK89606 rigid:/AFat0DrynAJ5ofEnoPSTThlxCE false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9BY14 uniprotkb:P16444 intact:EBI-12549378|ensembl:ENSP00000472769|uniprotkb:Q7L5R2|uniprotkb:Q9BPY7 intact:EBI-749514|uniprotkb:Q96AK2|uniprotkb:D3DX80|ensembl:ENSP00000261615|ensembl:ENSP00000376807|ensembl:ENSP00000397313 psi-mi:tx101_human(display_long)|uniprotkb:TEX101(gene name)|psi-mi:TEX101(display_short)|uniprotkb:Cell surface receptor NYD-SP8(gene name synonym)|uniprotkb:SGRG(gene name synonym)|uniprotkb:Scleroderma-associated autoantigen(gene name synonym)|uniprotkb:Spermatogenesis-related gene protein(gene name synonym)|uniprotkb:UNQ867/PRO1884(orf name) psi-mi:dpep1_human(display_long)|uniprotkb:Microsomal dipeptidase(gene name synonym)|uniprotkb:Renal dipeptidase(gene name synonym)|uniprotkb:Dehydropeptidase-I(gene name synonym)|uniprotkb:DPEP1(gene name)|psi-mi:DPEP1(display_short)|uniprotkb:MDP(gene name synonym)|uniprotkb:RDP(gene name synonym)|uniprotkb:Beta-lactamase(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Schiza et al. (2018) imex:IM-28077|pubmed:30097533 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-25505061|imex:IM-28077-3 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000131126(gene)|ensembl:ENST00000598265(transcript)|go:"GO:0001669"(acrosomal vesicle)|go:"GO:0002080"(acrosomal membrane)|go:"GO:0005576"(extracellular region)|go:"GO:0005886"(plasma membrane)|go:"GO:0007339"(binding of sperm to zona pellucida)|go:"GO:0009566"(fertilization)|go:"GO:0030317"(flagellated sperm motility)|go:"GO:0044853"(plasma membrane raft)|go:"GO:0046658"(anchored component of plasma membrane)|go:"GO:1901317"(regulation of flagellated sperm motility)|interpro:IPR016054(Ly-6 antigen / uPA receptor -like)|rcsb pdb:7BPR|reactome:R-HSA-163125|refseq:NP_001123483.1|refseq:NP_113639.4 refseq:NP_001121613.1|refseq:NP_004404.1|refseq:XP_011521227.1|refseq:XP_005256342.1|refseq:XP_005256343.1|ensembl:ENSG00000015413(gene)|ensembl:ENST00000261615(transcript)|ensembl:ENST00000393092(transcript)|ensembl:ENST00000421184(transcript)|go:"GO:0005615"(extracellular space)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0006629"(lipid metabolic process)|go:"GO:0006691"(leukotriene metabolic process)|go:"GO:0006749"(glutathione metabolic process)|go:"GO:0006751"(glutathione catabolic process)|go:"GO:0006954"(inflammatory response)|go:"GO:0008235"(metalloexopeptidase activity)|go:"GO:0008270"(zinc ion binding)|go:"GO:0008800"(beta-lactamase activity)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0016999"(antibiotic metabolic process)|go:"GO:0030054"(cell junction)|go:"GO:0030336"(negative regulation of cell migration)|go:"GO:0030593"(neutrophil chemotaxis)|go:"GO:0031225"(anchored component of membrane)|go:"GO:0031528"(microvillus membrane)|go:"GO:0034235"(GPI anchor binding)|go:"GO:0035690"|go:"GO:0043027"(cysteine-type endopeptidase inhibitor activity involved in apoptotic process)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043154"(negative regulation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0045177"(apical part of cell)|go:"GO:0050667"(homocysteine metabolic process)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070573"(metallodipeptidase activity)|go:"GO:0071277"(cellular response to calcium ion)|go:"GO:0071732"(cellular response to nitric oxide)|go:"GO:0072340"(cellular lactam catabolic process)|go:"GO:0072341"(modified amino acid binding)|interpro:IPR000180(Peptidase M19, renal dipeptidase, active site)|interpro:IPR008257(Peptidase M19, renal dipeptidase)|interpro:IPR028536|interpro:IPR032466|rcsb pdb:1ITQ|rcsb pdb:1ITU|reactome:R-HSA-2142691|reactome:R-HSA-5423646|reactome:R-HSA-9664535 - - - figure legend:Fig.2A,Supp Table S5|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-testis)|taxid:9606(Homo sapiens) - 2020/03/24 2021/11/30 rogid:ZE4tXTFi7lUCcIbCL4KHzY3a6xM9606 rogid:T2UzGo6JLAuXJHoywcc76WDjsJo9606 rigid:/AFat0DrynAJ5ofEnoPSTThlxCE false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9BY14 uniprotkb:Q15836 intact:EBI-12549378|ensembl:ENSP00000472769|uniprotkb:Q7L5R2|uniprotkb:Q9BPY7 intact:EBI-722343|uniprotkb:Q9BRV4|ensembl:ENSP00000054666 psi-mi:tx101_human(display_long)|uniprotkb:TEX101(gene name)|psi-mi:TEX101(display_short)|uniprotkb:Cell surface receptor NYD-SP8(gene name synonym)|uniprotkb:SGRG(gene name synonym)|uniprotkb:Scleroderma-associated autoantigen(gene name synonym)|uniprotkb:Spermatogenesis-related gene protein(gene name synonym)|uniprotkb:UNQ867/PRO1884(orf name) psi-mi:vamp3_human(display_long)|uniprotkb:Synaptobrevin-3(gene name synonym)|uniprotkb:Cellubrevin(gene name synonym)|uniprotkb:VAMP3(gene name)|psi-mi:VAMP3(display_short)|uniprotkb:SYB3(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Schiza et al. (2018) imex:IM-28077|pubmed:30097533 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-25505061|imex:IM-28077-3 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000131126(gene)|ensembl:ENST00000598265(transcript)|go:"GO:0001669"(acrosomal vesicle)|go:"GO:0002080"(acrosomal membrane)|go:"GO:0005576"(extracellular region)|go:"GO:0005886"(plasma membrane)|go:"GO:0007339"(binding of sperm to zona pellucida)|go:"GO:0009566"(fertilization)|go:"GO:0030317"(flagellated sperm motility)|go:"GO:0044853"(plasma membrane raft)|go:"GO:0046658"(anchored component of plasma membrane)|go:"GO:1901317"(regulation of flagellated sperm motility)|interpro:IPR016054(Ly-6 antigen / uPA receptor -like)|rcsb pdb:7BPR|reactome:R-HSA-163125|refseq:NP_001123483.1|refseq:NP_113639.4 refseq:NP_004772.1|dip:DIP-56422N|ensembl:ENSG00000049245(gene)|ensembl:ENST00000054666(transcript)|go:"GO:0001921"(positive regulation of receptor recycling)|go:"GO:0005484"(SNAP receptor activity)|go:"GO:0005769"(early endosome)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006887"(exocytosis)|go:"GO:0006904"(vesicle docking involved in exocytosis)|go:"GO:0006906"(vesicle fusion)|go:"GO:0009986"(cell surface)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016192"(vesicle-mediated transport)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0017075"(syntaxin-1 binding)|go:"GO:0017156"(calcium-ion regulated exocytosis)|go:"GO:0019905"(syntaxin binding)|go:"GO:0030133"(transport vesicle)|go:"GO:0030136"(clathrin-coated vesicle)|go:"GO:0030141"(secretory granule)|go:"GO:0030285"(integral component of synaptic vesicle membrane)|go:"GO:0030669"(clathrin-coated endocytic vesicle membrane)|go:"GO:0030670"(phagocytic vesicle membrane)|go:"GO:0031201"(SNARE complex)|go:"GO:0032588"(trans-Golgi network membrane)|go:"GO:0034446"(substrate adhesion-dependent cell spreading)|go:"GO:0035493"(SNARE complex assembly)|go:"GO:0042147"(retrograde transport, endosome to Golgi)|go:"GO:0043001"(Golgi to plasma membrane protein transport)|go:"GO:0043005"(neuron projection)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0055037"(recycling endosome)|go:"GO:0055038"(recycling endosome membrane)|go:"GO:0061025"(membrane fusion)|go:"GO:0065003"(protein-containing complex assembly)|go:"GO:0071346"(cellular response to interferon-gamma)|go:"GO:1903531"(negative regulation of secretion by cell)|interpro:IPR001388(Synaptobrevin)|interpro:IPR016444(Synaptobrevin, metazoa/fungi)|interpro:IPR042855|mint:Q15836|reactome:R-HSA-1236974|reactome:R-HSA-6811440|reactome:R-HSA-8856825|reactome:R-HSA-8856828|reactome:R-HSA-8980692|reactome:R-HSA-9013026|reactome:R-HSA-9013106|reactome:R-HSA-9013148|reactome:R-HSA-9013149|reactome:R-HSA-9013404|reactome:R-HSA-9013405|reactome:R-HSA-9013406|reactome:R-HSA-9013407|reactome:R-HSA-9013408|reactome:R-HSA-9013409|reactome:R-HSA-9013423|reactome:R-HSA-9035034 - - - figure legend:Fig.2A,Supp Table S5|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-testis)|taxid:9606(Homo sapiens) - 2020/03/24 2021/11/30 rogid:ZE4tXTFi7lUCcIbCL4KHzY3a6xM9606 rogid:JeCaIwh36OpRqMG0MFnpFZyN6jU9606 rigid:/AFat0DrynAJ5ofEnoPSTThlxCE false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9BY14 uniprotkb:Q07960 intact:EBI-12549378|ensembl:ENSP00000472769|uniprotkb:Q7L5R2|uniprotkb:Q9BPY7 intact:EBI-602762|uniprotkb:D3DQQ6|ensembl:ENSP00000310491 psi-mi:tx101_human(display_long)|uniprotkb:TEX101(gene name)|psi-mi:TEX101(display_short)|uniprotkb:Cell surface receptor NYD-SP8(gene name synonym)|uniprotkb:SGRG(gene name synonym)|uniprotkb:Scleroderma-associated autoantigen(gene name synonym)|uniprotkb:Spermatogenesis-related gene protein(gene name synonym)|uniprotkb:UNQ867/PRO1884(orf name) psi-mi:rhg01_human(display_long)|uniprotkb:Rho-type GTPase-activating protein 1(gene name synonym)|uniprotkb:Rho-related small GTPase protein activator(gene name synonym)|uniprotkb:p50-RhoGAP(gene name synonym)|uniprotkb:CDC42 GTPase-activating protein(gene name synonym)|uniprotkb:ARHGAP1(gene name)|psi-mi:ARHGAP1(display_short)|uniprotkb:CDC42GAP(gene name synonym)|uniprotkb:RHOGAP1(gene name synonym)|uniprotkb:GTPase-activating protein rhoGAP(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Schiza et al. (2018) imex:IM-28077|pubmed:30097533 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-25505061|imex:IM-28077-3 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000131126(gene)|ensembl:ENST00000598265(transcript)|go:"GO:0001669"(acrosomal vesicle)|go:"GO:0002080"(acrosomal membrane)|go:"GO:0005576"(extracellular region)|go:"GO:0005886"(plasma membrane)|go:"GO:0007339"(binding of sperm to zona pellucida)|go:"GO:0009566"(fertilization)|go:"GO:0030317"(flagellated sperm motility)|go:"GO:0044853"(plasma membrane raft)|go:"GO:0046658"(anchored component of plasma membrane)|go:"GO:1901317"(regulation of flagellated sperm motility)|interpro:IPR016054(Ly-6 antigen / uPA receptor -like)|rcsb pdb:7BPR|reactome:R-HSA-163125|refseq:NP_001123483.1|refseq:NP_113639.4 refseq:NP_004299.1|refseq:XP_011518397.1|dip:DIP-6081N|ensembl:ENSG00000175220(gene)|ensembl:ENST00000311956(transcript)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0007264"(small GTPase mediated signal transduction)|go:"GO:0007266"(Rho protein signal transduction)|go:"GO:0010008"(endosome membrane)|go:"GO:0016197"(endosomal transport)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0031267"(small GTPase binding)|go:"GO:0033572"(transferrin transport)|go:"GO:0045296"(cadherin binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051056"(regulation of small GTPase mediated signal transduction)|go:"GO:0070062"(extracellular exosome)|go:"GO:2001136"(negative regulation of endocytic recycling)|interpro:IPR000198(RhoGAP)|interpro:IPR001251(Cellular retinaldehyde-binding/triple function, C-terminal)|interpro:IPR008936(Rho GTPase activation protein)|interpro:IPR036865|mint:Q07960|rcsb pdb:1AM4|rcsb pdb:1GRN|rcsb pdb:1OW3|rcsb pdb:1RGP|rcsb pdb:1TX4|rcsb pdb:2NGR|rcsb pdb:5M6X|rcsb pdb:5M70|rcsb pdb:6R3V|reactome:R-HSA-8980692|reactome:R-HSA-9013026|reactome:R-HSA-9013106|reactome:R-HSA-9013148|reactome:R-HSA-9013149|reactome:R-HSA-9013404|reactome:R-HSA-9013405|reactome:R-HSA-9013406|reactome:R-HSA-9013408|reactome:R-HSA-9013409|reactome:R-HSA-9013423|reactome:R-HSA-9035034|reactome:R-HSA-9696270 - - - figure legend:Fig.2A,Supp Table S5|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-testis)|taxid:9606(Homo sapiens) - 2020/03/24 2021/11/30 rogid:ZE4tXTFi7lUCcIbCL4KHzY3a6xM9606 rogid:ceA3oLsnddhLiSbylS89P64mYBo9606 rigid:/AFat0DrynAJ5ofEnoPSTThlxCE false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9BY14 uniprotkb:Q8IWA5 intact:EBI-12549378|ensembl:ENSP00000472769|uniprotkb:Q7L5R2|uniprotkb:Q9BPY7 intact:EBI-11722896|uniprotkb:B2RBB1|uniprotkb:B3KNH3|uniprotkb:B4DFJ0|uniprotkb:F2Q9D7|uniprotkb:Q658V1|uniprotkb:Q658Z2|uniprotkb:Q6PJV7|uniprotkb:Q8N2F0|uniprotkb:Q9NY68|ensembl:ENSP00000336888 psi-mi:tx101_human(display_long)|uniprotkb:TEX101(gene name)|psi-mi:TEX101(display_short)|uniprotkb:Cell surface receptor NYD-SP8(gene name synonym)|uniprotkb:SGRG(gene name synonym)|uniprotkb:Scleroderma-associated autoantigen(gene name synonym)|uniprotkb:Spermatogenesis-related gene protein(gene name synonym)|uniprotkb:UNQ867/PRO1884(orf name) psi-mi:ctl2_human(display_long)|uniprotkb:SLC44A2(gene name)|psi-mi:SLC44A2(display_short)|uniprotkb:CTL2(gene name synonym)|uniprotkb:Solute carrier family 44 member 2(gene name synonym)|uniprotkb:PSEC0210(orf name) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Schiza et al. (2018) imex:IM-28077|pubmed:30097533 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-25505061|imex:IM-28077-3 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000131126(gene)|ensembl:ENST00000598265(transcript)|go:"GO:0001669"(acrosomal vesicle)|go:"GO:0002080"(acrosomal membrane)|go:"GO:0005576"(extracellular region)|go:"GO:0005886"(plasma membrane)|go:"GO:0007339"(binding of sperm to zona pellucida)|go:"GO:0009566"(fertilization)|go:"GO:0030317"(flagellated sperm motility)|go:"GO:0044853"(plasma membrane raft)|go:"GO:0046658"(anchored component of plasma membrane)|go:"GO:1901317"(regulation of flagellated sperm motility)|interpro:IPR016054(Ly-6 antigen / uPA receptor -like)|rcsb pdb:7BPR|reactome:R-HSA-163125|refseq:NP_001123483.1|refseq:NP_113639.4 refseq:NP_001138528.1|refseq:NP_065161.3|refseq:XP_005260054.1|ensembl:ENSG00000129353(gene)|ensembl:ENST00000335757(transcript)|go:"GO:0005739"(mitochondrion)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005886"(plasma membrane)|go:"GO:0006656"(phosphatidylcholine biosynthetic process)|go:"GO:0015220"(choline transmembrane transporter activity)|go:"GO:0015871"(choline transport)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0022857"(transmembrane transporter activity)|go:"GO:0035579"(specific granule membrane)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0055085"(transmembrane transport)|go:"GO:0070062"(extracellular exosome)|interpro:IPR007603(Protein of unknown function DUF580)|mint:Q8IWA5|reactome:R-HSA-1483191|reactome:R-HSA-425366|reactome:R-HSA-6798695 - - - figure legend:Fig.2A,Supp Table S5|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-testis)|taxid:9606(Homo sapiens) - 2020/03/24 2021/11/30 rogid:ZE4tXTFi7lUCcIbCL4KHzY3a6xM9606 rogid:SSl8Mo7YUgoqMyEdqv9w02Qj0iM9606 rigid:/AFat0DrynAJ5ofEnoPSTThlxCE false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9BY14 uniprotkb:P21589 intact:EBI-12549378|ensembl:ENSP00000472769|uniprotkb:Q7L5R2|uniprotkb:Q9BPY7 intact:EBI-6393623|ensembl:ENSP00000257770|uniprotkb:B3KQI8|uniprotkb:O75520|uniprotkb:Q5W116 psi-mi:tx101_human(display_long)|uniprotkb:TEX101(gene name)|psi-mi:TEX101(display_short)|uniprotkb:Cell surface receptor NYD-SP8(gene name synonym)|uniprotkb:SGRG(gene name synonym)|uniprotkb:Scleroderma-associated autoantigen(gene name synonym)|uniprotkb:Spermatogenesis-related gene protein(gene name synonym)|uniprotkb:UNQ867/PRO1884(orf name) psi-mi:5ntd_human(display_long)|uniprotkb:NT5E(gene name)|psi-mi:NT5E(display_short)|uniprotkb:NT5(gene name synonym)|uniprotkb:NTE(gene name synonym)|uniprotkb:Ecto-5'-nucleotidase(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Schiza et al. (2018) imex:IM-28077|pubmed:30097533 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-25505061|imex:IM-28077-3 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000131126(gene)|ensembl:ENST00000598265(transcript)|go:"GO:0001669"(acrosomal vesicle)|go:"GO:0002080"(acrosomal membrane)|go:"GO:0005576"(extracellular region)|go:"GO:0005886"(plasma membrane)|go:"GO:0007339"(binding of sperm to zona pellucida)|go:"GO:0009566"(fertilization)|go:"GO:0030317"(flagellated sperm motility)|go:"GO:0044853"(plasma membrane raft)|go:"GO:0046658"(anchored component of plasma membrane)|go:"GO:1901317"(regulation of flagellated sperm motility)|interpro:IPR016054(Ly-6 antigen / uPA receptor -like)|rcsb pdb:7BPR|reactome:R-HSA-163125|refseq:NP_001123483.1|refseq:NP_113639.4 ensembl:ENSG00000135318(gene)|ensembl:ENST00000257770(transcript)|go:"GO:0000166"(nucleotide binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006196"(AMP catabolic process)|go:"GO:0006259"(DNA metabolic process)|go:"GO:0007159"(leukocyte cell-cell adhesion)|go:"GO:0008253"(5'-nucleotidase activity)|go:"GO:0009897"(external side of plasma membrane)|go:"GO:0009986"(cell surface)|go:"GO:0016020"(membrane)|go:"GO:0031225"(anchored component of membrane)|go:"GO:0046032"(ADP catabolic process)|go:"GO:0046086"(adenosine biosynthetic process)|go:"GO:0046872"(metal ion binding)|go:"GO:0050728"(negative regulation of inflammatory response)|go:"GO:0070062"(extracellular exosome)|interpro:IPR004843(Metallophosphoesterase)|interpro:IPR006146(5'-Nucleotidase, conserved site)|interpro:IPR006179(5'-Nucleotidase and apyrase)|interpro:IPR008334(5'-Nucleotidase, C-terminal)|interpro:IPR029052|interpro:IPR036907|rcsb pdb:4H1S|rcsb pdb:4H1Y|rcsb pdb:4H2B|rcsb pdb:4H2F|rcsb pdb:4H2G|rcsb pdb:4H2I|rcsb pdb:6HXW|rcsb pdb:6S7F|rcsb pdb:6S7H|rcsb pdb:6TVE|rcsb pdb:6TVG|rcsb pdb:6TVX|rcsb pdb:6TW0|rcsb pdb:6TWA|rcsb pdb:6TWF|rcsb pdb:6XUE|rcsb pdb:6XUG|rcsb pdb:6XUQ|rcsb pdb:6YE1|rcsb pdb:6YE2|rcsb pdb:6Z9B|rcsb pdb:6Z9D|rcsb pdb:7JV8|rcsb pdb:7JV9|reactome:R-HSA-196807|reactome:R-HSA-73621|reactome:R-HSA-74259|reactome:R-HSA-9660826|refseq:NP_001191742.1|refseq:NP_002517.1|dip:DIP-59992N - - - figure legend:Fig.2A,Supp Table S5|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-testis)|taxid:9606(Homo sapiens) - 2020/03/24 2021/11/30 rogid:ZE4tXTFi7lUCcIbCL4KHzY3a6xM9606 rogid:Tn2KldD6XKIKJl1lnpG5WyvYS4w9606 rigid:/AFat0DrynAJ5ofEnoPSTThlxCE false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9BY14 uniprotkb:P39656 intact:EBI-12549378|ensembl:ENSP00000472769|uniprotkb:Q7L5R2|uniprotkb:Q9BPY7 intact:EBI-358866|uniprotkb:O43244|uniprotkb:Q8NI93|uniprotkb:Q9BUI2|uniprotkb:B2RDQ4|uniprotkb:Q5VWA5|ensembl:ENSP00000399457|uniprotkb:B4DJE3|uniprotkb:B4DLI2 psi-mi:tx101_human(display_long)|uniprotkb:TEX101(gene name)|psi-mi:TEX101(display_short)|uniprotkb:Cell surface receptor NYD-SP8(gene name synonym)|uniprotkb:SGRG(gene name synonym)|uniprotkb:Scleroderma-associated autoantigen(gene name synonym)|uniprotkb:Spermatogenesis-related gene protein(gene name synonym)|uniprotkb:UNQ867/PRO1884(orf name) psi-mi:ost48_human(display_long)|uniprotkb:DDOST(gene name)|psi-mi:DDOST(display_short)|uniprotkb:KIAA0115(gene name synonym)|uniprotkb:OST48(gene name synonym)|uniprotkb:OK/SW-cl.45(orf name) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Schiza et al. (2018) imex:IM-28077|pubmed:30097533 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-25505061|imex:IM-28077-3 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000131126(gene)|ensembl:ENST00000598265(transcript)|go:"GO:0001669"(acrosomal vesicle)|go:"GO:0002080"(acrosomal membrane)|go:"GO:0005576"(extracellular region)|go:"GO:0005886"(plasma membrane)|go:"GO:0007339"(binding of sperm to zona pellucida)|go:"GO:0009566"(fertilization)|go:"GO:0030317"(flagellated sperm motility)|go:"GO:0044853"(plasma membrane raft)|go:"GO:0046658"(anchored component of plasma membrane)|go:"GO:1901317"(regulation of flagellated sperm motility)|interpro:IPR016054(Ly-6 antigen / uPA receptor -like)|rcsb pdb:7BPR|reactome:R-HSA-163125|refseq:NP_001123483.1|refseq:NP_113639.4 refseq:NP_005207.2|ensembl:ENSG00000244038(gene)|ensembl:ENST00000415136(transcript)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005886"(plasma membrane)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0006486"(protein glycosylation)|go:"GO:0006487"(protein N-linked glycosylation)|go:"GO:0008047"(enzyme activator activity)|go:"GO:0008250"(oligosaccharyltransferase complex)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0018279"(protein N-linked glycosylation via asparagine)|go:"GO:0031647"(regulation of protein stability)|go:"GO:0034097"(response to cytokine)|go:"GO:0035577"(azurophil granule membrane)|go:"GO:0042110"(T cell activation)|go:"GO:0043231"(intracellular membrane-bounded organelle)|interpro:IPR005013(Dolichyl-diphosphooligosaccharide-protein glycosyltransferase 48kDa subunit)|mint:P39656|rcsb pdb:6S7O|rcsb pdb:6S7T|reactome:R-HSA-1799339|reactome:R-HSA-446203|reactome:R-HSA-6798695|reactome:R-HSA-879415|reactome:R-HSA-9694548 - - - figure legend:Fig.2A,Supp Table S5|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-testis)|taxid:9606(Homo sapiens) - 2020/03/24 2021/11/30 rogid:ZE4tXTFi7lUCcIbCL4KHzY3a6xM9606 rogid:utOlgvpqe2JHEJHk4gIp8tXwv/I9606 rigid:/AFat0DrynAJ5ofEnoPSTThlxCE false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9BY14 uniprotkb:Q16853 intact:EBI-12549378|ensembl:ENSP00000472769|uniprotkb:Q7L5R2|uniprotkb:Q9BPY7 intact:EBI-3921628|uniprotkb:B2RCI5|uniprotkb:Q45F94|ensembl:ENSP00000312326|uniprotkb:L0L8N9|uniprotkb:K7ESB3 psi-mi:tx101_human(display_long)|uniprotkb:TEX101(gene name)|psi-mi:TEX101(display_short)|uniprotkb:Cell surface receptor NYD-SP8(gene name synonym)|uniprotkb:SGRG(gene name synonym)|uniprotkb:Scleroderma-associated autoantigen(gene name synonym)|uniprotkb:Spermatogenesis-related gene protein(gene name synonym)|uniprotkb:UNQ867/PRO1884(orf name) psi-mi:aoc3_human(display_long)|uniprotkb:AOC3(gene name)|psi-mi:AOC3(display_short)|uniprotkb:VAP1(gene name synonym)|uniprotkb:Copper amine oxidase(gene name synonym)|uniprotkb:HPAO(gene name synonym)|uniprotkb:Semicarbazide-sensitive amine oxidase(gene name synonym)|uniprotkb:Vascular adhesion protein 1(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Schiza et al. (2018) imex:IM-28077|pubmed:30097533 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-25505061|imex:IM-28077-3 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000131126(gene)|ensembl:ENST00000598265(transcript)|go:"GO:0001669"(acrosomal vesicle)|go:"GO:0002080"(acrosomal membrane)|go:"GO:0005576"(extracellular region)|go:"GO:0005886"(plasma membrane)|go:"GO:0007339"(binding of sperm to zona pellucida)|go:"GO:0009566"(fertilization)|go:"GO:0030317"(flagellated sperm motility)|go:"GO:0044853"(plasma membrane raft)|go:"GO:0046658"(anchored component of plasma membrane)|go:"GO:1901317"(regulation of flagellated sperm motility)|interpro:IPR016054(Ly-6 antigen / uPA receptor -like)|rcsb pdb:7BPR|reactome:R-HSA-163125|refseq:NP_001123483.1|refseq:NP_113639.4 refseq:NP_001264660.1|refseq:NP_001264661.1|refseq:NP_003725.1|ensembl:ENSG00000131471(gene)|ensembl:ENST00000308423(transcript)|go:"GO:0005507"(copper ion binding)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005769"(early endosome)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0005902"(microvillus)|go:"GO:0006954"(inflammatory response)|go:"GO:0007155"(cell adhesion)|go:"GO:0008131"(primary amine oxidase activity)|go:"GO:0009308"(amine metabolic process)|go:"GO:0009986"(cell surface)|go:"GO:0016021"(integral component of membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0046677"(response to antibiotic)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0048038"(quinone binding)|go:"GO:0052593"("tryptamine:oxygen oxidoreductase (deaminating) activity")|go:"GO:0052594"("aminoacetone:oxygen oxidoreductase(deaminating) activity")|go:"GO:0052595"(aliphatic-amine oxidase activity)|go:"GO:0052596"("phenethylamine:oxygen oxidoreductase (deaminating) activity")|go:"GO:1902283"(negative regulation of primary amine oxidase activity)|interpro:IPR000269(Copper amine oxidase)|interpro:IPR015798(Copper amine oxidase, C-terminal)|interpro:IPR015800(Copper amine oxidase, N2-terminal)|interpro:IPR015802(Copper amine oxidase, N3-terminal)|interpro:IPR016182(Copper amine oxidase, N-terminal region)|interpro:IPR036460|rcsb pdb:1PU4|rcsb pdb:1US1|rcsb pdb:2C10|rcsb pdb:2C11|rcsb pdb:2Y73|rcsb pdb:2Y74|rcsb pdb:3ALA|rcsb pdb:4BTW|rcsb pdb:4BTX|rcsb pdb:4BTY|reactome:R-HSA-211945 - - - figure legend:Fig.2A,Supp Table S5|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-testis)|taxid:9606(Homo sapiens) - 2020/03/24 2021/11/30 rogid:ZE4tXTFi7lUCcIbCL4KHzY3a6xM9606 rogid:t7ZSUp32sGH23Gfa+V0Lult17Fw9606 rigid:/AFat0DrynAJ5ofEnoPSTThlxCE false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9BY14 uniprotkb:P36269 intact:EBI-12549378|ensembl:ENSP00000472769|uniprotkb:Q7L5R2|uniprotkb:Q9BPY7 intact:EBI-21840702|uniprotkb:Q53XM9|uniprotkb:Q6GMP0|uniprotkb:Q96FC1|uniprotkb:Q9UFM5|ensembl:ENSP00000330080 psi-mi:tx101_human(display_long)|uniprotkb:TEX101(gene name)|psi-mi:TEX101(display_short)|uniprotkb:Cell surface receptor NYD-SP8(gene name synonym)|uniprotkb:SGRG(gene name synonym)|uniprotkb:Scleroderma-associated autoantigen(gene name synonym)|uniprotkb:Spermatogenesis-related gene protein(gene name synonym)|uniprotkb:UNQ867/PRO1884(orf name) psi-mi:ggt5_human(display_long)|uniprotkb:Gamma-glutamyl transpeptidase-related enzyme(gene name synonym)|uniprotkb:Gamma-glutamyltransferase 5(gene name synonym)|uniprotkb:Gamma-glutamyltransferase-like activity 1(gene name synonym)|uniprotkb:Gamma-glutamyltranspeptidase 5(gene name synonym)|uniprotkb:Leukotriene-C4 hydrolase(gene name synonym)|uniprotkb:GGT5(gene name)|psi-mi:GGT5(display_short)|uniprotkb:GGTLA1(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Schiza et al. (2018) imex:IM-28077|pubmed:30097533 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-25505061|imex:IM-28077-3 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000131126(gene)|ensembl:ENST00000598265(transcript)|go:"GO:0001669"(acrosomal vesicle)|go:"GO:0002080"(acrosomal membrane)|go:"GO:0005576"(extracellular region)|go:"GO:0005886"(plasma membrane)|go:"GO:0007339"(binding of sperm to zona pellucida)|go:"GO:0009566"(fertilization)|go:"GO:0030317"(flagellated sperm motility)|go:"GO:0044853"(plasma membrane raft)|go:"GO:0046658"(anchored component of plasma membrane)|go:"GO:1901317"(regulation of flagellated sperm motility)|interpro:IPR016054(Ly-6 antigen / uPA receptor -like)|rcsb pdb:7BPR|reactome:R-HSA-163125|refseq:NP_001123483.1|refseq:NP_113639.4 refseq:NP_001093251.1|refseq:NP_001093252.1|refseq:NP_001289393.1|refseq:NP_001289394.1|refseq:NP_004112.2|interpro:IPR000101(Gamma-glutamyltranspeptidase)|interpro:IPR029055|interpro:IPR043137|interpro:IPR043138|reactome:R-HSA-174403|reactome:R-HSA-2142691|reactome:R-HSA-5423646|reactome:R-HSA-9664535|ensembl:ENSG00000099998(gene)|ensembl:ENST00000327365(transcript)|go:"GO:0000048"(peptidyltransferase activity)|go:"GO:0002951"("leukotriene-C(4) hydrolase")|go:"GO:0005886"(plasma membrane)|go:"GO:0006508"(proteolysis)|go:"GO:0006520"(cellular amino acid metabolic process)|go:"GO:0006631"(fatty acid metabolic process)|go:"GO:0006750"(glutathione biosynthetic process)|go:"GO:0006751"(glutathione catabolic process)|go:"GO:0006954"(inflammatory response)|go:"GO:0007283"(spermatogenesis)|go:"GO:0016021"(integral component of membrane)|go:"GO:0031226"(intrinsic component of plasma membrane)|go:"GO:0032355"(response to estradiol)|go:"GO:0032496"(response to lipopolysaccharide)|go:"GO:0034612"(response to tumor necrosis factor)|go:"GO:0036374"(glutathione hydrolase activity)|go:"GO:0102953"(hypoglycin A gamma-glutamyl transpeptidase activity)|go:"GO:0103068"(leukotriene C4 gamma-glutamyl transferase activity)|go:"GO:1901750"(leukotriene D4 biosynthetic process) - - - figure legend:Fig.2A,Supp Table S5|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-testis)|taxid:9606(Homo sapiens) - 2020/03/24 2021/11/30 rogid:ZE4tXTFi7lUCcIbCL4KHzY3a6xM9606 rogid:LeWzl5QO2lB4ojhExlTXH8yE/2U9606 rigid:/AFat0DrynAJ5ofEnoPSTThlxCE false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9BY14 uniprotkb:P04216 intact:EBI-12549378|ensembl:ENSP00000472769|uniprotkb:Q7L5R2|uniprotkb:Q9BPY7 intact:EBI-9071715|ensembl:ENSP00000284240|ensembl:ENSP00000431301|uniprotkb:Q9NSP1|uniprotkb:Q16008 psi-mi:tx101_human(display_long)|uniprotkb:TEX101(gene name)|psi-mi:TEX101(display_short)|uniprotkb:Cell surface receptor NYD-SP8(gene name synonym)|uniprotkb:SGRG(gene name synonym)|uniprotkb:Scleroderma-associated autoantigen(gene name synonym)|uniprotkb:Spermatogenesis-related gene protein(gene name synonym)|uniprotkb:UNQ867/PRO1884(orf name) psi-mi:thy1_human(display_long)|uniprotkb:CDw90(gene name synonym)|uniprotkb:Thy-1 antigen(gene name synonym)|uniprotkb:THY1(gene name)|psi-mi:THY1(display_short) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Schiza et al. (2018) imex:IM-28077|pubmed:30097533 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-25505061|imex:IM-28077-3 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000131126(gene)|ensembl:ENST00000598265(transcript)|go:"GO:0001669"(acrosomal vesicle)|go:"GO:0002080"(acrosomal membrane)|go:"GO:0005576"(extracellular region)|go:"GO:0005886"(plasma membrane)|go:"GO:0007339"(binding of sperm to zona pellucida)|go:"GO:0009566"(fertilization)|go:"GO:0030317"(flagellated sperm motility)|go:"GO:0044853"(plasma membrane raft)|go:"GO:0046658"(anchored component of plasma membrane)|go:"GO:1901317"(regulation of flagellated sperm motility)|interpro:IPR016054(Ly-6 antigen / uPA receptor -like)|rcsb pdb:7BPR|reactome:R-HSA-163125|refseq:NP_001123483.1|refseq:NP_113639.4 refseq:NP_006279.2|refseq:NP_001298089.1|refseq:NP_001298091.1|ensembl:ENSG00000154096(gene)|ensembl:ENST00000284240(transcript)|ensembl:ENST00000528522(transcript)|go:"GO:0001525"(angiogenesis)|go:"GO:0001952"(regulation of cell-matrix adhesion)|go:"GO:0002693"(positive regulation of cellular extravasation)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005178"(integrin binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0005925"(focal adhesion)|go:"GO:0006469"(negative regulation of protein kinase activity)|go:"GO:0007010"(cytoskeleton organization)|go:"GO:0007229"(integrin-mediated signaling pathway)|go:"GO:0007267"(cell-cell signaling)|go:"GO:0009897"(external side of plasma membrane)|go:"GO:0009986"(cell surface)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030336"(negative regulation of cell migration)|go:"GO:0030425"(dendrite)|go:"GO:0030426"(growth cone)|go:"GO:0030673"(axolemma)|go:"GO:0031362"(anchored component of external side of plasma membrane)|go:"GO:0032590"(dendrite membrane)|go:"GO:0032809"(neuronal cell body membrane)|go:"GO:0034116"(positive regulation of heterotypic cell-cell adhesion)|go:"GO:0034235"(GPI anchor binding)|go:"GO:0043113"(receptor clustering)|go:"GO:0043547"(positive regulation of GTPase activity)|go:"GO:0045121"(membrane raft)|go:"GO:0046549"(retinal cone cell development)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0048041"(focal adhesion assembly)|go:"GO:0050771"(negative regulation of axonogenesis)|go:"GO:0050852"(T cell receptor signaling pathway)|go:"GO:0050860"(negative regulation of T cell receptor signaling pathway)|go:"GO:0050870"(positive regulation of T cell activation)|go:"GO:0051281"(positive regulation of release of sequestered calcium ion into cytosol)|go:"GO:0051894"(positive regulation of focal adhesion assembly)|go:"GO:0061099"(negative regulation of protein tyrosine kinase activity)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070571"(negative regulation of neuron projection regeneration)|go:"GO:0098609"(cell-cell adhesion)|go:"GO:2000298"(regulation of Rho-dependent protein serine/threonine kinase activity)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR013106(Immunoglobulin V-set)|interpro:IPR013151(Immunoglobulin)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR033292|interpro:IPR036179|mint:P04216|reactome:R-HSA-163125 - - - figure legend:Fig.2A,Supp Table S5|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-testis)|taxid:9606(Homo sapiens) - 2020/03/24 2021/11/30 rogid:ZE4tXTFi7lUCcIbCL4KHzY3a6xM9606 rogid:oJQb/vrYoN49IHy3OI4SmCXYtJY9606 rigid:/AFat0DrynAJ5ofEnoPSTThlxCE false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9BY14 uniprotkb:Q14108 intact:EBI-12549378|ensembl:ENSP00000472769|uniprotkb:Q7L5R2|uniprotkb:Q9BPY7 intact:EBI-1564650|uniprotkb:Q53Y63|uniprotkb:B4DKD8|uniprotkb:E7EM68|ensembl:ENSP00000264896 psi-mi:tx101_human(display_long)|uniprotkb:TEX101(gene name)|psi-mi:TEX101(display_short)|uniprotkb:Cell surface receptor NYD-SP8(gene name synonym)|uniprotkb:SGRG(gene name synonym)|uniprotkb:Scleroderma-associated autoantigen(gene name synonym)|uniprotkb:Spermatogenesis-related gene protein(gene name synonym)|uniprotkb:UNQ867/PRO1884(orf name) psi-mi:scrb2_human(display_long)|uniprotkb:Lysosome membrane protein II(gene name synonym)|uniprotkb:Scavenger receptor class B member 2(gene name synonym)|uniprotkb:85 kDa lysosomal membrane sialoglycoprotein(gene name synonym)|uniprotkb:CD36 antigen-like 2(gene name synonym)|uniprotkb:SCARB2(gene name)|psi-mi:SCARB2(display_short)|uniprotkb:CD36L2(gene name synonym)|uniprotkb:LIMPII(gene name synonym)|uniprotkb:LIMP2(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Schiza et al. (2018) imex:IM-28077|pubmed:30097533 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-25505061|imex:IM-28077-3 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000131126(gene)|ensembl:ENST00000598265(transcript)|go:"GO:0001669"(acrosomal vesicle)|go:"GO:0002080"(acrosomal membrane)|go:"GO:0005576"(extracellular region)|go:"GO:0005886"(plasma membrane)|go:"GO:0007339"(binding of sperm to zona pellucida)|go:"GO:0009566"(fertilization)|go:"GO:0030317"(flagellated sperm motility)|go:"GO:0044853"(plasma membrane raft)|go:"GO:0046658"(anchored component of plasma membrane)|go:"GO:1901317"(regulation of flagellated sperm motility)|interpro:IPR016054(Ly-6 antigen / uPA receptor -like)|rcsb pdb:7BPR|reactome:R-HSA-163125|refseq:NP_001123483.1|refseq:NP_113639.4 refseq:NP_001191184.1|refseq:NP_005497.1|ensembl:ENSG00000138760(gene)|ensembl:ENST00000264896(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001618"(virus receptor activity)|go:"GO:0001786"(phosphatidylserine binding)|go:"GO:0004888"(transmembrane signaling receptor activity)|go:"GO:0005044"(scavenger receptor activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005886"(plasma membrane)|go:"GO:0005925"(focal adhesion)|go:"GO:0006622"(protein targeting to lysosome)|go:"GO:0006898"(receptor-mediated endocytosis)|go:"GO:0007605"(sensory perception of sound)|go:"GO:0010008"(endosome membrane)|go:"GO:0010467"(gene expression)|go:"GO:0010976"(positive regulation of neuron projection development)|go:"GO:0015485"(cholesterol binding)|go:"GO:0015917"(aminophospholipid transport)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0019899"(enzyme binding)|go:"GO:0030666"(endocytic vesicle membrane)|go:"GO:0030669"(clathrin-coated endocytic vesicle membrane)|go:"GO:0031210"(phosphatidylcholine binding)|go:"GO:0031902"(late endosome membrane)|go:"GO:0038024"(cargo receptor activity)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043202"(lysosomal lumen)|go:"GO:0043471"(regulation of cellular carbohydrate catabolic process)|go:"GO:0051087"(chaperone binding)|go:"GO:0070062"(extracellular exosome)|go:"GO:1904978"(regulation of endosome organization)|go:"GO:1905123"(regulation of glucosylceramidase activity)|go:"GO:1905671"(regulation of lysosome organization)|interpro:IPR002159(CD36 antigen)|interpro:IPR005429(Lysosome membrane protein II)|mint:Q14108|rcsb pdb:4F7B|rcsb pdb:4Q4B|rcsb pdb:4Q4F|rcsb pdb:4TVZ|rcsb pdb:4TW0|rcsb pdb:4TW2|rcsb pdb:5UPH|rcsb pdb:5XBM|rcsb pdb:6I2K|reactome:R-HSA-8856825|reactome:R-HSA-8856828 - - - figure legend:Fig.2A,Supp Table S5|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-testis)|taxid:9606(Homo sapiens) - 2020/03/24 2021/11/30 rogid:ZE4tXTFi7lUCcIbCL4KHzY3a6xM9606 rogid:FXyG5dJv7OqGjSgl5slIqNxUqoI9606 rigid:/AFat0DrynAJ5ofEnoPSTThlxCE false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9BY14 uniprotkb:Q9BY14 intact:EBI-12549378|ensembl:ENSP00000472769|uniprotkb:Q7L5R2|uniprotkb:Q9BPY7 intact:EBI-12549378|ensembl:ENSP00000472769|uniprotkb:Q7L5R2|uniprotkb:Q9BPY7 psi-mi:tx101_human(display_long)|uniprotkb:TEX101(gene name)|psi-mi:TEX101(display_short)|uniprotkb:Cell surface receptor NYD-SP8(gene name synonym)|uniprotkb:SGRG(gene name synonym)|uniprotkb:Scleroderma-associated autoantigen(gene name synonym)|uniprotkb:Spermatogenesis-related gene protein(gene name synonym)|uniprotkb:UNQ867/PRO1884(orf name) psi-mi:tx101_human(display_long)|uniprotkb:TEX101(gene name)|psi-mi:TEX101(display_short)|uniprotkb:Cell surface receptor NYD-SP8(gene name synonym)|uniprotkb:SGRG(gene name synonym)|uniprotkb:Scleroderma-associated autoantigen(gene name synonym)|uniprotkb:Spermatogenesis-related gene protein(gene name synonym)|uniprotkb:UNQ867/PRO1884(orf name) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Schiza et al. (2018) imex:IM-28077|pubmed:30097533 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-25505061|imex:IM-28077-3 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000131126(gene)|ensembl:ENST00000598265(transcript)|go:"GO:0001669"(acrosomal vesicle)|go:"GO:0002080"(acrosomal membrane)|go:"GO:0005576"(extracellular region)|go:"GO:0005886"(plasma membrane)|go:"GO:0007339"(binding of sperm to zona pellucida)|go:"GO:0009566"(fertilization)|go:"GO:0030317"(flagellated sperm motility)|go:"GO:0044853"(plasma membrane raft)|go:"GO:0046658"(anchored component of plasma membrane)|go:"GO:1901317"(regulation of flagellated sperm motility)|interpro:IPR016054(Ly-6 antigen / uPA receptor -like)|rcsb pdb:7BPR|reactome:R-HSA-163125|refseq:NP_001123483.1|refseq:NP_113639.4 ensembl:ENSG00000131126(gene)|ensembl:ENST00000598265(transcript)|go:"GO:0001669"(acrosomal vesicle)|go:"GO:0002080"(acrosomal membrane)|go:"GO:0005576"(extracellular region)|go:"GO:0005886"(plasma membrane)|go:"GO:0007339"(binding of sperm to zona pellucida)|go:"GO:0009566"(fertilization)|go:"GO:0030317"(flagellated sperm motility)|go:"GO:0044853"(plasma membrane raft)|go:"GO:0046658"(anchored component of plasma membrane)|go:"GO:1901317"(regulation of flagellated sperm motility)|interpro:IPR016054(Ly-6 antigen / uPA receptor -like)|rcsb pdb:7BPR|reactome:R-HSA-163125|refseq:NP_001123483.1|refseq:NP_113639.4 - - - figure legend:Fig.2A,Supp Table S5|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-testis)|taxid:9606(Homo sapiens) - 2020/03/24 2021/11/30 rogid:ZE4tXTFi7lUCcIbCL4KHzY3a6xM9606 rogid:ZE4tXTFi7lUCcIbCL4KHzY3a6xM9606 rigid:/AFat0DrynAJ5ofEnoPSTThlxCE false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9BY14 uniprotkb:Q9BYF1 intact:EBI-12549378|ensembl:ENSP00000472769|uniprotkb:Q7L5R2|uniprotkb:Q9BPY7 intact:EBI-7730807|ensembl:ENSP00000252519|ensembl:ENSP00000389326|ensembl:ENSP00000504103|ensembl:ENSP00000505992|intact:EBI-25767352|uniprotkb:Q9UFZ6|uniprotkb:Q9NRA7|intact:MINT-4538816|uniprotkb:C7ECU1|uniprotkb:Q6UWP0|uniprotkb:Q86WT0|uniprotkb:A0A7D6JAD5|intact:EBI-15814450 psi-mi:tx101_human(display_long)|uniprotkb:TEX101(gene name)|psi-mi:TEX101(display_short)|uniprotkb:Cell surface receptor NYD-SP8(gene name synonym)|uniprotkb:SGRG(gene name synonym)|uniprotkb:Scleroderma-associated autoantigen(gene name synonym)|uniprotkb:Spermatogenesis-related gene protein(gene name synonym)|uniprotkb:UNQ867/PRO1884(orf name) psi-mi:ace2_human(display_long)|uniprotkb:ACE2(gene name)|psi-mi:ACE2(display_short)|uniprotkb:UNQ868/PRO1885(orf name)|uniprotkb:Angiotensin-converting enzyme homolog(gene name synonym)|uniprotkb:Metalloprotease MPROT15(gene name synonym)|uniprotkb:Angiotensin-converting enzyme-related carboxypeptidase(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Schiza et al. (2018) imex:IM-28077|pubmed:30097533 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-25505302|imex:IM-28077-5 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000131126(gene)|ensembl:ENST00000598265(transcript)|go:"GO:0001669"(acrosomal vesicle)|go:"GO:0002080"(acrosomal membrane)|go:"GO:0005576"(extracellular region)|go:"GO:0005886"(plasma membrane)|go:"GO:0007339"(binding of sperm to zona pellucida)|go:"GO:0009566"(fertilization)|go:"GO:0030317"(flagellated sperm motility)|go:"GO:0044853"(plasma membrane raft)|go:"GO:0046658"(anchored component of plasma membrane)|go:"GO:1901317"(regulation of flagellated sperm motility)|interpro:IPR016054(Ly-6 antigen / uPA receptor -like)|rcsb pdb:7BPR|reactome:R-HSA-163125|refseq:NP_001123483.1|refseq:NP_113639.4 ensembl:ENST00000252519(transcript)|ensembl:ENST00000427411(transcript)|ensembl:ENST00000678073(transcript)|ensembl:ENST00000680121(transcript)|go:"GO:0001618"(virus receptor activity)|go:"GO:0001817"(regulation of cytokine production)|go:"GO:0002003"(angiotensin maturation)|go:"GO:0003051"(angiotensin-mediated drinking behavior)|go:"GO:0003081"(regulation of systemic arterial blood pressure by renin-angiotensin)|go:"GO:0004175"(endopeptidase activity)|go:"GO:0004180"(carboxypeptidase activity)|go:"GO:0004181"(metallocarboxypeptidase activity)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0005788"(endoplasmic reticulum lumen)|go:"GO:0005886"(plasma membrane)|go:"GO:0005929"(cilium)|go:"GO:0006508"(proteolysis)|go:"GO:0008237"(metallopeptidase activity)|go:"GO:0008241"(peptidyl-dipeptidase activity)|go:"GO:0008270"(zinc ion binding)|go:"GO:0009986"(cell surface)|go:"GO:0015827"(tryptophan transport)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0019229"(regulation of vasoconstriction)|go:"GO:0022898"(regulation of transmembrane transporter activity)|go:"GO:0030666"(endocytic vesicle membrane)|go:"GO:0031526"(brush border membrane)|go:"GO:0042127"(regulation of cell population proliferation)|go:"GO:0042802"(identical protein binding)|go:"GO:0045121"(membrane raft)|go:"GO:0046718"(viral entry into host cell)|go:"GO:0046813"(receptor-mediated virion attachment to host cell)|ensembl:ENSG00000130234(gene)|go:"GO:0051957"(positive regulation of amino acid transport)|go:"GO:0060452"(positive regulation of cardiac muscle contraction)|go:"GO:0070062"(extracellular exosome)|go:"GO:0097746"(blood vessel diameter maintenance)|go:"GO:1903598"(positive regulation of gap junction assembly)|go:"GO:1903779"(regulation of cardiac conduction)|go:"GO:1905737"(positive regulation of L-proline import across plasma membrane)|go:"GO:2000272"(negative regulation of signaling receptor activity)|go:"GO:2000379"(positive regulation of reactive oxygen species metabolic process)|interpro:IPR001548(Peptidase M2, peptidyl-dipeptidase A)|interpro:IPR031588|mint:Q9BYF1|rcsb pdb:1R42|rcsb pdb:1R4L|rcsb pdb:1XJP|rcsb pdb:2AJF|rcsb pdb:3D0G|rcsb pdb:3D0H|rcsb pdb:3D0I|rcsb pdb:3KBH|rcsb pdb:3SCI|rcsb pdb:3SCJ|rcsb pdb:3SCK|rcsb pdb:3SCL|rcsb pdb:6ACG|rcsb pdb:6ACJ|rcsb pdb:6ACK|rcsb pdb:6CS2|rcsb pdb:6LZG|rcsb pdb:6M0J|rcsb pdb:6M17|rcsb pdb:6M18|go:"GO:0050727"(regulation of inflammatory response)|rcsb pdb:6M1D|rcsb pdb:6VW1|rcsb pdb:7A91|rcsb pdb:7A92|rcsb pdb:7A94|rcsb pdb:7A95|rcsb pdb:7A96|rcsb pdb:7A97|rcsb pdb:7A98|rcsb pdb:7BH9|rcsb pdb:7CT5|rcsb pdb:7DDO|rcsb pdb:7DDP|rcsb pdb:7DF4|rcsb pdb:7DMU|rcsb pdb:7DWX|rcsb pdb:7DX4|rcsb pdb:7DX5|rcsb pdb:7DX6|rcsb pdb:7DX7|rcsb pdb:7DX8|rcsb pdb:7DX9|rcsb pdb:7JVO|rcsb pdb:7KJ2|rcsb pdb:7KJ3|rcsb pdb:7KJ4|rcsb pdb:7KMB|rcsb pdb:7KMS|rcsb pdb:7KMZ|rcsb pdb:7KNB|rcsb pdb:7KNE|rcsb pdb:7KNH|rcsb pdb:7L0N|rcsb pdb:7L7F|rcsb pdb:7LO4|rcsb pdb:7MJM|rcsb pdb:7MJN|rcsb pdb:7NXC|reactome:R-HSA-2022377|reactome:R-HSA-9678110|reactome:R-HSA-9679191|reactome:R-HSA-9694614|rcsb pdb:7KNI|dip:DIP-44689N|refseq:NP_068576.1 - - comment:mint|function:Carboxypeptidase which converts angiotensin I to angiotensin 1-9, a peptide of unknown function, and angiotensin II to angiotensin 1-7, a vasodilator. Also able to hydrolyze apelin-13 and dynorphin-13 with high efficiency. May be an important regulator of heart function. In case of human coronaviruses SARS and HCoV-NL63 infections, serve as functional receptor for the spike glycoprotein of both coronaviruses figure legend:Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-testis)|taxid:9606(Homo sapiens) - 2020/03/24 2020/04/07 rogid:ZE4tXTFi7lUCcIbCL4KHzY3a6xM9606 rogid:ZxuR6gzxz4Ns+hYH5uksGdn8S7o9606 rigid:MKZD74P9H6EUxrJA8lHGdXF33tU false - - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q9BY14 uniprotkb:Q13508 intact:EBI-12549378|ensembl:ENSP00000472769|uniprotkb:Q7L5R2|uniprotkb:Q9BPY7 intact:EBI-3904355|uniprotkb:Q96HL1|uniprotkb:Q8WVJ7|uniprotkb:Q6FHT7|uniprotkb:Q53XW3|uniprotkb:Q93069|ensembl:ENSP00000348064 psi-mi:tx101_human(display_long)|uniprotkb:TEX101(gene name)|psi-mi:TEX101(display_short)|uniprotkb:Cell surface receptor NYD-SP8(gene name synonym)|uniprotkb:SGRG(gene name synonym)|uniprotkb:Scleroderma-associated autoantigen(gene name synonym)|uniprotkb:Spermatogenesis-related gene protein(gene name synonym)|uniprotkb:UNQ867/PRO1884(orf name) psi-mi:nar3_human(display_long)|uniprotkb:ART3(gene name)|psi-mi:ART3(display_short)|uniprotkb:TMART(gene name synonym)|uniprotkb:"Mono(ADP-ribosyl)transferase 3"(gene name synonym)|uniprotkb:"NAD(P)(+)--arginine ADP-ribosyltransferase 3"(gene name synonym)|uniprotkb:ADP-ribosyltransferase C2 and C3 toxin-like 3(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Schiza et al. (2018) imex:IM-28077|pubmed:30097533 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-25505302|imex:IM-28077-5 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000131126(gene)|ensembl:ENST00000598265(transcript)|go:"GO:0001669"(acrosomal vesicle)|go:"GO:0002080"(acrosomal membrane)|go:"GO:0005576"(extracellular region)|go:"GO:0005886"(plasma membrane)|go:"GO:0007339"(binding of sperm to zona pellucida)|go:"GO:0009566"(fertilization)|go:"GO:0030317"(flagellated sperm motility)|go:"GO:0044853"(plasma membrane raft)|go:"GO:0046658"(anchored component of plasma membrane)|go:"GO:1901317"(regulation of flagellated sperm motility)|interpro:IPR016054(Ly-6 antigen / uPA receptor -like)|rcsb pdb:7BPR|reactome:R-HSA-163125|refseq:NP_001123483.1|refseq:NP_113639.4 refseq:NP_001123488.1|refseq:NP_001123489.1|refseq:NP_001170.2|ensembl:ENSG00000156219(gene)|ensembl:ENST00000355810(transcript)|go:"GO:0003950"(NAD+ ADP-ribosyltransferase activity)|go:"GO:0005576"(extracellular region)|go:"GO:0005886"(plasma membrane)|go:"GO:0006471"(protein ADP-ribosylation)|go:"GO:0031225"(anchored component of membrane)|go:"GO:0031226"(intrinsic component of plasma membrane)|go:"GO:0070062"(extracellular exosome)|go:"GO:0106274"(NAD+-protein-arginine ADP-ribosyltransferase activity)|go:"GO:0106275"(NADP+-protein-arginine ADP-ribosyltransferase activity)|interpro:IPR000768("NAD:arginine ADP-ribosyltransferase, ART")|reactome:R-HSA-163125|go:"GO:0018120"(peptidyl-arginine ADP-ribosylation) - - - figure legend:Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-testis)|taxid:9606(Homo sapiens) - 2020/03/24 2020/04/07 rogid:ZE4tXTFi7lUCcIbCL4KHzY3a6xM9606 rogid:JxQqlEa6lC6ZXSyTp7aaYCNxq189606 rigid:MKZD74P9H6EUxrJA8lHGdXF33tU false - - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q9BY14 uniprotkb:Q9H4B8 intact:EBI-12549378|ensembl:ENSP00000472769|uniprotkb:Q7L5R2|uniprotkb:Q9BPY7 intact:EBI-20843342|ensembl:ENSP00000268793|uniprotkb:B3KQ48|uniprotkb:Q6PEZ5|uniprotkb:Q6UXE4 psi-mi:tx101_human(display_long)|uniprotkb:TEX101(gene name)|psi-mi:TEX101(display_short)|uniprotkb:Cell surface receptor NYD-SP8(gene name synonym)|uniprotkb:SGRG(gene name synonym)|uniprotkb:Scleroderma-associated autoantigen(gene name synonym)|uniprotkb:Spermatogenesis-related gene protein(gene name synonym)|uniprotkb:UNQ867/PRO1884(orf name) psi-mi:dpep3_human(display_long)|uniprotkb:DPEP3(gene name)|psi-mi:DPEP3(display_short)|uniprotkb:UNQ834/PRO1772(orf name) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Schiza et al. (2018) imex:IM-28077|pubmed:30097533 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-25505302|imex:IM-28077-5 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000131126(gene)|ensembl:ENST00000598265(transcript)|go:"GO:0001669"(acrosomal vesicle)|go:"GO:0002080"(acrosomal membrane)|go:"GO:0005576"(extracellular region)|go:"GO:0005886"(plasma membrane)|go:"GO:0007339"(binding of sperm to zona pellucida)|go:"GO:0009566"(fertilization)|go:"GO:0030317"(flagellated sperm motility)|go:"GO:0044853"(plasma membrane raft)|go:"GO:0046658"(anchored component of plasma membrane)|go:"GO:1901317"(regulation of flagellated sperm motility)|interpro:IPR016054(Ly-6 antigen / uPA receptor -like)|rcsb pdb:7BPR|reactome:R-HSA-163125|refseq:NP_001123483.1|refseq:NP_113639.4 ensembl:ENSG00000141096(gene)|ensembl:ENST00000268793(transcript)|go:"GO:0001669"(acrosomal vesicle)|go:"GO:0005886"(plasma membrane)|go:"GO:0016805"(dipeptidase activity)|go:"GO:0031225"(anchored component of membrane)|go:"GO:0046872"(metal ion binding)|go:"GO:0070573"(metallodipeptidase activity)|interpro:IPR000180(Peptidase M19, renal dipeptidase, active site)|interpro:IPR008257(Peptidase M19, renal dipeptidase)|interpro:IPR028531|interpro:IPR032466|rcsb pdb:6VGO|rcsb pdb:6VGR|reactome:R-HSA-2142691|reactome:R-HSA-5423646|reactome:R-HSA-9664535|refseq:NP_001123230.1|refseq:NP_071752.3 - - - figure legend:Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-testis)|taxid:9606(Homo sapiens) - 2020/03/24 2020/04/07 rogid:ZE4tXTFi7lUCcIbCL4KHzY3a6xM9606 rogid:wSsO6DP0LPkeh39DF/dAvEktuTE9606 rigid:MKZD74P9H6EUxrJA8lHGdXF33tU false - - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q9BY14 uniprotkb:P05556 intact:EBI-12549378|ensembl:ENSP00000472769|uniprotkb:Q7L5R2|uniprotkb:Q9BPY7 intact:EBI-703066|intact:EBI-4289597|ensembl:ENSP00000303351|ensembl:ENSP00000379350|ensembl:ENSP00000398029|ensembl:ENSP00000404546|ensembl:ENSP00000502882|ensembl:ENSP00000503546|ensembl:ENSP00000503916|ensembl:ENSP00000504205|ensembl:ENSP00000504444|uniprotkb:Q7Z3V1|uniprotkb:Q8WUM6|uniprotkb:P78466|uniprotkb:P78467|uniprotkb:Q13089|uniprotkb:Q13090|uniprotkb:Q13091|uniprotkb:Q13212|uniprotkb:Q14622|uniprotkb:Q14647|uniprotkb:A8K6N2|uniprotkb:Q29RW2|uniprotkb:D3DRX9|uniprotkb:D3DRY3|uniprotkb:D3DRY4|uniprotkb:D3DRY5 psi-mi:tx101_human(display_long)|uniprotkb:TEX101(gene name)|psi-mi:TEX101(display_short)|uniprotkb:Cell surface receptor NYD-SP8(gene name synonym)|uniprotkb:SGRG(gene name synonym)|uniprotkb:Scleroderma-associated autoantigen(gene name synonym)|uniprotkb:Spermatogenesis-related gene protein(gene name synonym)|uniprotkb:UNQ867/PRO1884(orf name) psi-mi:itb1_human(display_long)|uniprotkb:Fibronectin receptor subunit beta(gene name synonym)|uniprotkb:VLA-4 subunit beta(gene name synonym)|uniprotkb:ITGB1(gene name)|psi-mi:ITGB1(display_short)|uniprotkb:FNRB(gene name synonym)|uniprotkb:MDF2(gene name synonym)|uniprotkb:MSK12(gene name synonym)|uniprotkb:Glycoprotein IIa(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Schiza et al. (2018) imex:IM-28077|pubmed:30097533 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-25505302|imex:IM-28077-5 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000131126(gene)|ensembl:ENST00000598265(transcript)|go:"GO:0001669"(acrosomal vesicle)|go:"GO:0002080"(acrosomal membrane)|go:"GO:0005576"(extracellular region)|go:"GO:0005886"(plasma membrane)|go:"GO:0007339"(binding of sperm to zona pellucida)|go:"GO:0009566"(fertilization)|go:"GO:0030317"(flagellated sperm motility)|go:"GO:0044853"(plasma membrane raft)|go:"GO:0046658"(anchored component of plasma membrane)|go:"GO:1901317"(regulation of flagellated sperm motility)|interpro:IPR016054(Ly-6 antigen / uPA receptor -like)|rcsb pdb:7BPR|reactome:R-HSA-163125|refseq:NP_001123483.1|refseq:NP_113639.4 go:"GO:0001618"(virus receptor activity)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0001708"(cell fate specification)|go:"GO:0001726"(ruffle)|go:"GO:0001968"(fibronectin binding)|go:"GO:0002020"(protease binding)|go:"GO:0002042"(cell migration involved in sprouting angiogenesis)|go:"GO:0003779"(actin binding)|go:"GO:0005178"(integrin binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0005925"(focal adhesion)|go:"GO:0006909"(phagocytosis)|go:"GO:0006968"(cellular defense response)|go:"GO:0007155"(cell adhesion)|go:"GO:0007156"(homophilic cell adhesion via plasma membrane adhesion molecules)|go:"GO:0007159"(leukocyte cell-cell adhesion)|go:"GO:0007160"(cell-matrix adhesion)|go:"GO:0007161"(calcium-independent cell-matrix adhesion)|go:"GO:0007229"(integrin-mediated signaling pathway)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0008354"(germ cell migration)|go:"GO:0008542"(visual learning)|go:"GO:0009897"(external side of plasma membrane)|go:"GO:0009986"(cell surface)|go:"GO:0010008"(endosome membrane)|go:"GO:0010710"(regulation of collagen catabolic process)|go:"GO:0010763"(positive regulation of fibroblast migration)|go:"GO:0014704"(intercalated disc)|go:"GO:0015026"(coreceptor activity)|go:"GO:0016020"(membrane)|go:"GO:0016477"(cell migration)|go:"GO:0021943"(formation of radial glial scaffolds)|go:"GO:0023035"(CD40 signaling pathway)|go:"GO:0030027"(lamellipodium)|go:"GO:0030030"(cell projection organization)|go:"GO:0030032"(lamellipodium assembly)|go:"GO:0030175"(filopodium)|go:"GO:0030183"(B cell differentiation)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0031589"(cell-substrate adhesion)|go:"GO:0031594"(neuromuscular junction)|go:"GO:0031623"(receptor internalization)|go:"GO:0032154"(cleavage furrow)|go:"GO:0032587"(ruffle membrane)|go:"GO:0033627"(cell adhesion mediated by integrin)|go:"GO:0033631"(cell-cell adhesion mediated by integrin)|go:"GO:0034113"(heterotypic cell-cell adhesion)|go:"GO:0034665"(integrin alpha1-beta1 complex)|go:"GO:0034666"(integrin alpha2-beta1 complex)|go:"GO:0034667"(integrin alpha3-beta1 complex)|go:"GO:0034668"(integrin alpha4-beta1 complex)|go:"GO:0034674"(integrin alpha5-beta1 complex)|go:"GO:0034677"(integrin alpha7-beta1 complex)|go:"GO:0034678"(integrin alpha8-beta1 complex)|go:"GO:0034680"(integrin alpha10-beta1 complex)|go:"GO:0034681"(integrin alpha11-beta1 complex)|go:"GO:0035024"(negative regulation of Rho protein signal transduction)|go:"GO:0035633"(maintenance of blood-brain barrier)|go:"GO:0035748"(myelin sheath abaxonal region)|go:"GO:0042383"(sarcolemma)|go:"GO:0042470"(melanosome)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043197"(dendritic spine)|go:"GO:0043235"(receptor complex)|go:"GO:0043236"(laminin binding)|go:"GO:0043547"(positive regulation of GTPase activity)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045121"(membrane raft)|go:"GO:0045214"(sarcomere organization)|go:"GO:0045296"(cadherin binding)|go:"GO:0045596"(negative regulation of cell differentiation)|go:"GO:0045766"(positive regulation of angiogenesis)|go:"GO:0046872"(metal ion binding)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0048333"(mesodermal cell differentiation)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0048675"(axon extension)|go:"GO:0048813"(dendrite morphogenesis)|go:"GO:0050839"(cell adhesion molecule binding)|go:"GO:0050901"(leukocyte tethering or rolling)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0051897"(positive regulation of protein kinase B signaling)|go:"GO:0051951"(positive regulation of glutamate uptake involved in transmission of nerve impulse)|go:"GO:0055007"(cardiac muscle cell differentiation)|go:"GO:0055037"(recycling endosome)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071404"(cellular response to low-density lipoprotein particle stimulus)|go:"GO:0071711"(basement membrane organization)|go:"GO:0090303"(positive regulation of wound healing)|go:"GO:0097386"(glial cell projection)|go:"GO:0098639"(collagen binding involved in cell-matrix adhesion)|go:"GO:0098685"(Schaffer collateral - CA1 synapse)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099699"(integral component of synaptic membrane)|go:"GO:0150003"(regulation of spontaneous synaptic transmission)|go:"GO:0150103"(reactive gliosis)|go:"GO:1901979"(regulation of inward rectifier potassium channel activity)|go:"GO:1903078"(positive regulation of protein localization to plasma membrane)|go:"GO:1990782"(protein tyrosine kinase binding)|go:"GO:2000273"(positive regulation of signaling receptor activity)|go:"GO:2000811"(negative regulation of anoikis)|interpro:IPR002369(Integrin beta subunit, N-terminal)|interpro:IPR012896(Integrin beta subunit, tail)|interpro:IPR013111(EGF, extracellular)|interpro:IPR014836(Integrin beta subunit, cytoplasmic)|interpro:IPR015812(Integrin beta subunit)|interpro:IPR016201(Plexin-like fold)|interpro:IPR027071|interpro:IPR032695|interpro:IPR033760|interpro:IPR036349|interpro:IPR036465|interpro:IPR040622|mint:P05556|rcsb pdb:1K11|rcsb pdb:1LHA|rcsb pdb:3G9W|rcsb pdb:3T9K|rcsb pdb:3VI3|rcsb pdb:3VI4|rcsb pdb:4DX9|rcsb pdb:4WJK|rcsb pdb:4WK0|rcsb pdb:4WK2|rcsb pdb:4WK4|rcsb pdb:7CEB|rcsb pdb:7CEC|rcsb pdb:7NWL|reactome:R-HSA-1566948|reactome:R-HSA-1566977|reactome:R-HSA-198933|ensembl:ENSG00000150093(gene)|ensembl:ENST00000302278(transcript)|ensembl:ENST00000396033(transcript)|ensembl:ENST00000417122(transcript)|ensembl:ENST00000437302(transcript)|ensembl:ENST00000677999(transcript)|ensembl:ENST00000678701(transcript)|ensembl:ENST00000678943(transcript)|ensembl:ENST00000678952(transcript)|ensembl:ENST00000678989(transcript)|go:"GO:0000082"(G1/S transition of mitotic cell cycle)|go:"GO:0000132"(establishment of mitotic spindle orientation)|refseq:NP_002202.2|refseq:NP_391988.1|refseq:NP_596867.1|dip:DIP-312N|reactome:R-HSA-202733|reactome:R-HSA-210991|reactome:R-HSA-2129379|reactome:R-HSA-216083|reactome:R-HSA-3000157|reactome:R-HSA-3000170|reactome:R-HSA-3000178|reactome:R-HSA-416700|reactome:R-HSA-445144|reactome:R-HSA-446343|reactome:R-HSA-447041|reactome:R-HSA-5663220|reactome:R-HSA-6785807|reactome:R-HSA-75892|reactome:R-HSA-8874081|reactome:R-HSA-8875513|reactome:R-HSA-9013149|reactome:R-HSA-9013404|reactome:R-HSA-9013408|reactome:R-HSA-9013423|reactome:R-HSA-9609690|reactome:R-HSA-9679191 - - - figure legend:Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-testis)|taxid:9606(Homo sapiens) - 2020/03/24 2020/04/07 rogid:ZE4tXTFi7lUCcIbCL4KHzY3a6xM9606 rogid:FZ+lMRS6Zq07A8Lgmf5C6vEXUgM9606 rigid:MKZD74P9H6EUxrJA8lHGdXF33tU false - - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q9BY14 uniprotkb:P21589 intact:EBI-12549378|ensembl:ENSP00000472769|uniprotkb:Q7L5R2|uniprotkb:Q9BPY7 intact:EBI-6393623|ensembl:ENSP00000257770|uniprotkb:B3KQI8|uniprotkb:O75520|uniprotkb:Q5W116 psi-mi:tx101_human(display_long)|uniprotkb:TEX101(gene name)|psi-mi:TEX101(display_short)|uniprotkb:Cell surface receptor NYD-SP8(gene name synonym)|uniprotkb:SGRG(gene name synonym)|uniprotkb:Scleroderma-associated autoantigen(gene name synonym)|uniprotkb:Spermatogenesis-related gene protein(gene name synonym)|uniprotkb:UNQ867/PRO1884(orf name) psi-mi:5ntd_human(display_long)|uniprotkb:NT5E(gene name)|psi-mi:NT5E(display_short)|uniprotkb:NT5(gene name synonym)|uniprotkb:NTE(gene name synonym)|uniprotkb:Ecto-5'-nucleotidase(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Schiza et al. (2018) imex:IM-28077|pubmed:30097533 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-25505302|imex:IM-28077-5 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000131126(gene)|ensembl:ENST00000598265(transcript)|go:"GO:0001669"(acrosomal vesicle)|go:"GO:0002080"(acrosomal membrane)|go:"GO:0005576"(extracellular region)|go:"GO:0005886"(plasma membrane)|go:"GO:0007339"(binding of sperm to zona pellucida)|go:"GO:0009566"(fertilization)|go:"GO:0030317"(flagellated sperm motility)|go:"GO:0044853"(plasma membrane raft)|go:"GO:0046658"(anchored component of plasma membrane)|go:"GO:1901317"(regulation of flagellated sperm motility)|interpro:IPR016054(Ly-6 antigen / uPA receptor -like)|rcsb pdb:7BPR|reactome:R-HSA-163125|refseq:NP_001123483.1|refseq:NP_113639.4 ensembl:ENSG00000135318(gene)|ensembl:ENST00000257770(transcript)|go:"GO:0000166"(nucleotide binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006196"(AMP catabolic process)|go:"GO:0006259"(DNA metabolic process)|go:"GO:0007159"(leukocyte cell-cell adhesion)|go:"GO:0008253"(5'-nucleotidase activity)|go:"GO:0009897"(external side of plasma membrane)|go:"GO:0009986"(cell surface)|go:"GO:0016020"(membrane)|go:"GO:0031225"(anchored component of membrane)|go:"GO:0046032"(ADP catabolic process)|go:"GO:0046086"(adenosine biosynthetic process)|go:"GO:0046872"(metal ion binding)|go:"GO:0050728"(negative regulation of inflammatory response)|go:"GO:0070062"(extracellular exosome)|interpro:IPR004843(Metallophosphoesterase)|interpro:IPR006146(5'-Nucleotidase, conserved site)|interpro:IPR006179(5'-Nucleotidase and apyrase)|interpro:IPR008334(5'-Nucleotidase, C-terminal)|interpro:IPR029052|interpro:IPR036907|rcsb pdb:4H1S|rcsb pdb:4H1Y|rcsb pdb:4H2B|rcsb pdb:4H2F|rcsb pdb:4H2G|rcsb pdb:4H2I|rcsb pdb:6HXW|rcsb pdb:6S7F|rcsb pdb:6S7H|rcsb pdb:6TVE|rcsb pdb:6TVG|rcsb pdb:6TVX|rcsb pdb:6TW0|rcsb pdb:6TWA|rcsb pdb:6TWF|rcsb pdb:6XUE|rcsb pdb:6XUG|rcsb pdb:6XUQ|rcsb pdb:6YE1|rcsb pdb:6YE2|rcsb pdb:6Z9B|rcsb pdb:6Z9D|rcsb pdb:7JV8|rcsb pdb:7JV9|reactome:R-HSA-196807|reactome:R-HSA-73621|reactome:R-HSA-74259|reactome:R-HSA-9660826|refseq:NP_001191742.1|refseq:NP_002517.1|dip:DIP-59992N - - - figure legend:Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-testis)|taxid:9606(Homo sapiens) - 2020/03/24 2020/04/07 rogid:ZE4tXTFi7lUCcIbCL4KHzY3a6xM9606 rogid:Tn2KldD6XKIKJl1lnpG5WyvYS4w9606 rigid:MKZD74P9H6EUxrJA8lHGdXF33tU false - - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q9BY14 uniprotkb:Q16651 intact:EBI-12549378|ensembl:ENSP00000472769|uniprotkb:Q7L5R2|uniprotkb:Q9BPY7 intact:EBI-7246681|uniprotkb:B4DWP2|intact:MINT-5000236|uniprotkb:Q9UCA3|ensembl:ENSP00000319730 psi-mi:tx101_human(display_long)|uniprotkb:TEX101(gene name)|psi-mi:TEX101(display_short)|uniprotkb:Cell surface receptor NYD-SP8(gene name synonym)|uniprotkb:SGRG(gene name synonym)|uniprotkb:Scleroderma-associated autoantigen(gene name synonym)|uniprotkb:Spermatogenesis-related gene protein(gene name synonym)|uniprotkb:UNQ867/PRO1884(orf name) psi-mi:prss8_human(display_long)|uniprotkb:Channel-activating protease 1(gene name synonym)|uniprotkb:PRSS8(gene name)|psi-mi:PRSS8(display_short)|uniprotkb:Serine protease 8(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Schiza et al. (2018) imex:IM-28077|pubmed:30097533 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-25505396|imex:IM-28077-7 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000131126(gene)|ensembl:ENST00000598265(transcript)|go:"GO:0001669"(acrosomal vesicle)|go:"GO:0002080"(acrosomal membrane)|go:"GO:0005576"(extracellular region)|go:"GO:0005886"(plasma membrane)|go:"GO:0007339"(binding of sperm to zona pellucida)|go:"GO:0009566"(fertilization)|go:"GO:0030317"(flagellated sperm motility)|go:"GO:0044853"(plasma membrane raft)|go:"GO:0046658"(anchored component of plasma membrane)|go:"GO:1901317"(regulation of flagellated sperm motility)|interpro:IPR016054(Ly-6 antigen / uPA receptor -like)|rcsb pdb:7BPR|reactome:R-HSA-163125|refseq:NP_001123483.1|refseq:NP_113639.4 refseq:NP_002764.1|ensembl:ENSG00000052344(gene)|ensembl:ENST00000317508(transcript)|go:"GO:0004252"(serine-type endopeptidase activity)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0005886"(plasma membrane)|go:"GO:0008236"(serine-type peptidase activity)|go:"GO:0010765"(positive regulation of sodium ion transport)|go:"GO:0016021"(integral component of membrane)|go:"GO:0070062"(extracellular exosome)|interpro:IPR001254(Peptidase S1 and S6, chymotrypsin/Hap)|go:"GO:0017080"(sodium channel regulator activity)|interpro:IPR001314(Peptidase S1A, chymotrypsin)|interpro:IPR009003(Peptidase, trypsin-like serine and cysteine)|interpro:IPR018114|interpro:IPR033116|interpro:IPR043504|rcsb pdb:3DFJ|rcsb pdb:3DFL|rcsb pdb:3E0N|rcsb pdb:3E0P|rcsb pdb:3E16|rcsb pdb:3E1X|rcsb pdb:3FVF|rcsb pdb:3GYL|rcsb pdb:3GYM|reactome:R-HSA-6809371 - - comment:mint|comment:homomint|function:Possesses a trypsin-like cleavage specificity comment:"Proteins significantly enriched by immunoprecipitation with 34ED556 (T1) anti-TEX101 antibody in human sperm cells from pre-vasectomy semen samples."|figure legend:Fig. 2B, supplemental Table S6|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-spermatozoa)|taxid:9606(Homo sapiens) - 2020/03/24 2020/04/07 rogid:ZE4tXTFi7lUCcIbCL4KHzY3a6xM9606 rogid:QnM4TQgJm3CP4GkJAvtsEfJ62uk9606 rigid:TX1oljMyfkimcULEvhCJR/BRAW4 false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9BY14 uniprotkb:P15309 intact:EBI-12549378|ensembl:ENSP00000472769|uniprotkb:Q7L5R2|uniprotkb:Q9BPY7 intact:EBI-1222012|uniprotkb:Q96KY0|uniprotkb:Q96QK9|uniprotkb:Q96QM0|uniprotkb:D3DNC6|uniprotkb:Q5FBY0|ensembl:ENSP00000337471 psi-mi:tx101_human(display_long)|uniprotkb:TEX101(gene name)|psi-mi:TEX101(display_short)|uniprotkb:Cell surface receptor NYD-SP8(gene name synonym)|uniprotkb:SGRG(gene name synonym)|uniprotkb:Scleroderma-associated autoantigen(gene name synonym)|uniprotkb:Spermatogenesis-related gene protein(gene name synonym)|uniprotkb:UNQ867/PRO1884(orf name) psi-mi:ppap_human(display_long)|uniprotkb:ACP3(gene name)|psi-mi:ACP3(display_short)|uniprotkb:5'-nucleotidase(gene name synonym)|uniprotkb:ACPP(gene name synonym)|uniprotkb:Acid phosphatase 3(gene name synonym)|uniprotkb:Ecto-5'-nucleotidase(gene name synonym)|uniprotkb:Thiamine monophosphatase(gene name synonym)|uniprotkb:Protein tyrosine phosphatase ACP3(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Schiza et al. (2018) imex:IM-28077|pubmed:30097533 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-25505396|imex:IM-28077-7 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000131126(gene)|ensembl:ENST00000598265(transcript)|go:"GO:0001669"(acrosomal vesicle)|go:"GO:0002080"(acrosomal membrane)|go:"GO:0005576"(extracellular region)|go:"GO:0005886"(plasma membrane)|go:"GO:0007339"(binding of sperm to zona pellucida)|go:"GO:0009566"(fertilization)|go:"GO:0030317"(flagellated sperm motility)|go:"GO:0044853"(plasma membrane raft)|go:"GO:0046658"(anchored component of plasma membrane)|go:"GO:1901317"(regulation of flagellated sperm motility)|interpro:IPR016054(Ly-6 antigen / uPA receptor -like)|rcsb pdb:7BPR|reactome:R-HSA-163125|refseq:NP_001123483.1|refseq:NP_113639.4 refseq:NP_001090.2|refseq:NP_001127666.1|refseq:NP_001278966.1|ensembl:ENSG00000014257(gene)|ensembl:ENST00000336375(transcript)|go:"GO:0003993"(acid phosphatase activity)|go:"GO:0004725"(protein tyrosine phosphatase activity)|go:"GO:0005615"(extracellular space)|go:"GO:0005634"(nucleus)|go:"GO:0005764"(lysosome)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006144"(purine nucleobase metabolic process)|go:"GO:0006772"(thiamine metabolic process)|go:"GO:0007040"(lysosome organization)|go:"GO:0008253"(5'-nucleotidase activity)|go:"GO:0009117"(nucleotide metabolic process)|go:"GO:0012506"(vesicle membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016311"(dephosphorylation)|go:"GO:0016791"(phosphatase activity)|go:"GO:0030175"(filopodium)|go:"GO:0035577"(azurophil granule membrane)|go:"GO:0042131"(thiamine phosphate phosphatase activity)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0046085"(adenosine metabolic process)|go:"GO:0051930"(regulation of sensory perception of pain)|go:"GO:0052642"(lysophosphatidic acid phosphatase activity)|go:"GO:0060168"(positive regulation of adenosine receptor signaling pathway)|go:"GO:0070062"(extracellular exosome)|interpro:IPR000560(Histidine acid phosphatase)|interpro:IPR029033|interpro:IPR033379|mint:P15309|rcsb pdb:1CVI|rcsb pdb:1ND5|rcsb pdb:1ND6|rcsb pdb:2HPA|rcsb pdb:2L3H|rcsb pdb:2L77|rcsb pdb:2L79|rcsb pdb:2MG0|rcsb pdb:3PPD|reactome:R-HSA-6798695 - - - comment:"Proteins significantly enriched by immunoprecipitation with 34ED556 (T1) anti-TEX101 antibody in human sperm cells from pre-vasectomy semen samples."|figure legend:Fig. 2B, supplemental Table S6|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-spermatozoa)|taxid:9606(Homo sapiens) - 2020/03/24 2020/04/07 rogid:ZE4tXTFi7lUCcIbCL4KHzY3a6xM9606 rogid:FLbVR5/u8MLUphen4TZZaKOPY7U9606 rigid:TX1oljMyfkimcULEvhCJR/BRAW4 false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9BY14 uniprotkb:Q8TDM5 intact:EBI-12549378|ensembl:ENSP00000472769|uniprotkb:Q7L5R2|uniprotkb:Q9BPY7 intact:EBI-21844912|ensembl:ENSP00000312774 psi-mi:tx101_human(display_long)|uniprotkb:TEX101(gene name)|psi-mi:TEX101(display_short)|uniprotkb:Cell surface receptor NYD-SP8(gene name synonym)|uniprotkb:SGRG(gene name synonym)|uniprotkb:Scleroderma-associated autoantigen(gene name synonym)|uniprotkb:Spermatogenesis-related gene protein(gene name synonym)|uniprotkb:UNQ867/PRO1884(orf name) psi-mi:saca4_human(display_long)|uniprotkb:Sperm acrosomal membrane-associated protein 14(gene name synonym)|uniprotkb:UNQ3046/PRO9862(orf name)|uniprotkb:SPACA4(gene name)|psi-mi:SPACA4(display_short)|uniprotkb:SAMP14(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Schiza et al. (2018) imex:IM-28077|pubmed:30097533 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-25505396|imex:IM-28077-7 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000131126(gene)|ensembl:ENST00000598265(transcript)|go:"GO:0001669"(acrosomal vesicle)|go:"GO:0002080"(acrosomal membrane)|go:"GO:0005576"(extracellular region)|go:"GO:0005886"(plasma membrane)|go:"GO:0007339"(binding of sperm to zona pellucida)|go:"GO:0009566"(fertilization)|go:"GO:0030317"(flagellated sperm motility)|go:"GO:0044853"(plasma membrane raft)|go:"GO:0046658"(anchored component of plasma membrane)|go:"GO:1901317"(regulation of flagellated sperm motility)|interpro:IPR016054(Ly-6 antigen / uPA receptor -like)|rcsb pdb:7BPR|reactome:R-HSA-163125|refseq:NP_001123483.1|refseq:NP_113639.4 refseq:NP_598005.1|ensembl:ENSG00000177202(gene)|go:"GO:0001669"(acrosomal vesicle)|go:"GO:0005576"(extracellular region)|go:"GO:0005886"(plasma membrane)|go:"GO:0007155"(cell adhesion)|go:"GO:0031225"(anchored component of membrane)|interpro:IPR016054(Ly-6 antigen / uPA receptor -like)|reactome:R-HSA-163125|ensembl:ENST00000321762(transcript) - - - comment:"Proteins significantly enriched by immunoprecipitation with 34ED556 (T1) anti-TEX101 antibody in human sperm cells from pre-vasectomy semen samples."|figure legend:Fig. 2B, supplemental Table S6|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-spermatozoa)|taxid:9606(Homo sapiens) - 2020/03/24 2020/04/07 rogid:ZE4tXTFi7lUCcIbCL4KHzY3a6xM9606 rogid:omyfhI+EnTkGwr/wujnsc+xkwww9606 rigid:TX1oljMyfkimcULEvhCJR/BRAW4 false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9BY14 uniprotkb:P61019 intact:EBI-12549378|ensembl:ENSP00000472769|uniprotkb:Q7L5R2|uniprotkb:Q9BPY7 intact:EBI-752037|uniprotkb:P08886|uniprotkb:B2R5W8|uniprotkb:B4DMQ5|ensembl:ENSP00000262646 psi-mi:tx101_human(display_long)|uniprotkb:TEX101(gene name)|psi-mi:TEX101(display_short)|uniprotkb:Cell surface receptor NYD-SP8(gene name synonym)|uniprotkb:SGRG(gene name synonym)|uniprotkb:Scleroderma-associated autoantigen(gene name synonym)|uniprotkb:Spermatogenesis-related gene protein(gene name synonym)|uniprotkb:UNQ867/PRO1884(orf name) psi-mi:rab2a_human(display_long)|uniprotkb:RAB2A(gene name)|psi-mi:RAB2A(display_short)|uniprotkb:RAB2(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Schiza et al. (2018) imex:IM-28077|pubmed:30097533 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-25505396|imex:IM-28077-7 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000131126(gene)|ensembl:ENST00000598265(transcript)|go:"GO:0001669"(acrosomal vesicle)|go:"GO:0002080"(acrosomal membrane)|go:"GO:0005576"(extracellular region)|go:"GO:0005886"(plasma membrane)|go:"GO:0007339"(binding of sperm to zona pellucida)|go:"GO:0009566"(fertilization)|go:"GO:0030317"(flagellated sperm motility)|go:"GO:0044853"(plasma membrane raft)|go:"GO:0046658"(anchored component of plasma membrane)|go:"GO:1901317"(regulation of flagellated sperm motility)|interpro:IPR016054(Ly-6 antigen / uPA receptor -like)|rcsb pdb:7BPR|reactome:R-HSA-163125|refseq:NP_001123483.1|refseq:NP_113639.4 refseq:NP_002856.1|refseq:NP_001229573.1|dip:DIP-316N|ensembl:ENSG00000104388(gene)|ensembl:ENST00000262646(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0007030"(Golgi organization)|go:"GO:0015031"(protein transport)|go:"GO:0019003"(GDP binding)|go:"GO:0033116"(endoplasmic reticulum-Golgi intermediate compartment membrane)|go:"GO:0042470"(melanosome)|go:"GO:0070062"(extracellular exosome)|interpro:IPR001806(Ras GTPase)|interpro:IPR005225(Small GTP-binding protein)|interpro:IPR027417|rcsb pdb:1Z0A|reactome:R-HSA-162658|reactome:R-HSA-8873719 - - - comment:"Proteins significantly enriched by immunoprecipitation with 34ED556 (T1) anti-TEX101 antibody in human sperm cells from pre-vasectomy semen samples."|figure legend:Fig. 2B, supplemental Table S6|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-spermatozoa)|taxid:9606(Homo sapiens) - 2020/03/24 2020/04/07 rogid:ZE4tXTFi7lUCcIbCL4KHzY3a6xM9606 rogid:MyG011KOkAtsvE2hU/fs21CEe/M9606 rigid:TX1oljMyfkimcULEvhCJR/BRAW4 false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9BY14 uniprotkb:P07954 intact:EBI-12549378|ensembl:ENSP00000472769|uniprotkb:Q7L5R2|uniprotkb:Q9BPY7 intact:EBI-1050358|uniprotkb:B1ANK7|ensembl:ENSP00000355518 psi-mi:tx101_human(display_long)|uniprotkb:TEX101(gene name)|psi-mi:TEX101(display_short)|uniprotkb:Cell surface receptor NYD-SP8(gene name synonym)|uniprotkb:SGRG(gene name synonym)|uniprotkb:Scleroderma-associated autoantigen(gene name synonym)|uniprotkb:Spermatogenesis-related gene protein(gene name synonym)|uniprotkb:UNQ867/PRO1884(orf name) psi-mi:fumh_human(display_long)|uniprotkb:FH(gene name)|psi-mi:FH(display_short) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Schiza et al. (2018) imex:IM-28077|pubmed:30097533 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-25505396|imex:IM-28077-7 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000131126(gene)|ensembl:ENST00000598265(transcript)|go:"GO:0001669"(acrosomal vesicle)|go:"GO:0002080"(acrosomal membrane)|go:"GO:0005576"(extracellular region)|go:"GO:0005886"(plasma membrane)|go:"GO:0007339"(binding of sperm to zona pellucida)|go:"GO:0009566"(fertilization)|go:"GO:0030317"(flagellated sperm motility)|go:"GO:0044853"(plasma membrane raft)|go:"GO:0046658"(anchored component of plasma membrane)|go:"GO:1901317"(regulation of flagellated sperm motility)|interpro:IPR016054(Ly-6 antigen / uPA receptor -like)|rcsb pdb:7BPR|reactome:R-HSA-163125|refseq:NP_001123483.1|refseq:NP_113639.4 refseq:NP_000134.2|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0005829"(cytosol)|go:"GO:0006099"(tricarboxylic acid cycle)|go:"GO:0006106"(fumarate metabolic process)|go:"GO:0006108"(malate metabolic process)|go:"GO:0006281"(DNA repair)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0035861"(site of double-strand break)|go:"GO:0042393"(histone binding)|go:"GO:0045239"(tricarboxylic acid cycle enzyme complex)|go:"GO:0048873"(homeostasis of number of cells within a tissue)|go:"GO:0070062"(extracellular exosome)|go:"GO:0120162"(positive regulation of cold-induced thermogenesis)|go:"GO:2001034"(positive regulation of double-strand break repair via nonhomologous end joining)|interpro:IPR000362(Fumarate lyase)|interpro:IPR005677(Fumarate hydratase, class II)|ensembl:ENSG00000091483(gene)|interpro:IPR008948(L-Aspartase-like)|interpro:IPR018951|ensembl:ENST00000366560(transcript)|interpro:IPR020557|interpro:IPR022761|go:"GO:0000050"(urea cycle)|interpro:IPR024083|mint:P07954|rcsb pdb:3E04|go:"GO:0000415"(negative regulation of histone H3-K36 methylation)|rcsb pdb:5D6B|go:"GO:0000821"(regulation of arginine metabolic process)|rcsb pdb:5UPP|rcsb pdb:6EBT|rcsb pdb:6V8F|rcsb pdb:6VBE|go:"GO:0004333"(fumarate hydratase activity)|reactome:R-HSA-71403|go:"GO:0005634"(nucleus)|go:"GO:0005694"(chromosome)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|dip:DIP-46920N - - - comment:"Proteins significantly enriched by immunoprecipitation with 34ED556 (T1) anti-TEX101 antibody in human sperm cells from pre-vasectomy semen samples."|figure legend:Fig. 2B, supplemental Table S6|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-spermatozoa)|taxid:9606(Homo sapiens) - 2020/03/24 2020/04/07 rogid:ZE4tXTFi7lUCcIbCL4KHzY3a6xM9606 rogid:Jukx6wt0vi49nxgaTzdz5x1Q2Mc9606 rigid:TX1oljMyfkimcULEvhCJR/BRAW4 false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9BY14 uniprotkb:P14406 intact:EBI-12549378|ensembl:ENSP00000472769|uniprotkb:Q7L5R2|uniprotkb:Q9BPY7 intact:EBI-2606666|uniprotkb:Q5TF59|uniprotkb:Q6FGI2|uniprotkb:Q3MIH5|uniprotkb:B2R5E1|ensembl:ENSP00000506727 psi-mi:tx101_human(display_long)|uniprotkb:TEX101(gene name)|psi-mi:TEX101(display_short)|uniprotkb:Cell surface receptor NYD-SP8(gene name synonym)|uniprotkb:SGRG(gene name synonym)|uniprotkb:Scleroderma-associated autoantigen(gene name synonym)|uniprotkb:Spermatogenesis-related gene protein(gene name synonym)|uniprotkb:UNQ867/PRO1884(orf name) psi-mi:cx7a2_human(display_long)|uniprotkb:COX7AL(gene name synonym)|uniprotkb:Cytochrome c oxidase subunit VIIa-liver/heart(gene name synonym)|uniprotkb:COX7A2(gene name)|psi-mi:COX7A2(display_short) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Schiza et al. (2018) imex:IM-28077|pubmed:30097533 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-25505396|imex:IM-28077-7 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000131126(gene)|ensembl:ENST00000598265(transcript)|go:"GO:0001669"(acrosomal vesicle)|go:"GO:0002080"(acrosomal membrane)|go:"GO:0005576"(extracellular region)|go:"GO:0005886"(plasma membrane)|go:"GO:0007339"(binding of sperm to zona pellucida)|go:"GO:0009566"(fertilization)|go:"GO:0030317"(flagellated sperm motility)|go:"GO:0044853"(plasma membrane raft)|go:"GO:0046658"(anchored component of plasma membrane)|go:"GO:1901317"(regulation of flagellated sperm motility)|interpro:IPR016054(Ly-6 antigen / uPA receptor -like)|rcsb pdb:7BPR|reactome:R-HSA-163125|refseq:NP_001123483.1|refseq:NP_113639.4 refseq:NP_001856.2|ensembl:ENSG00000112695(gene)|ensembl:ENST00000684430(transcript)|go:"GO:0002082"(regulation of oxidative phosphorylation)|go:"GO:0005746"(mitochondrial respirasome)|go:"GO:0005751"(mitochondrial respiratory chain complex IV)|go:"GO:0006123"(mitochondrial electron transport, cytochrome c to oxygen)|go:"GO:0009055"(electron transfer activity)|go:"GO:0016021"(integral component of membrane)|go:"GO:0097250"(mitochondrial respirasome assembly)|interpro:IPR003177(Cytochrome c oxidase, subunit VIIa)|interpro:IPR036539|interpro:IPR039297|mint:P14406|rcsb pdb:5Z62 - - - comment:"Proteins significantly enriched by immunoprecipitation with 34ED556 (T1) anti-TEX101 antibody in human sperm cells from pre-vasectomy semen samples."|figure legend:Fig. 2B, supplemental Table S6|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-spermatozoa)|taxid:9606(Homo sapiens) - 2020/03/24 2020/04/07 rogid:ZE4tXTFi7lUCcIbCL4KHzY3a6xM9606 rogid:krjTK658npBV4G6gH28GJhVqBkY9606 rigid:TX1oljMyfkimcULEvhCJR/BRAW4 false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9BY14 uniprotkb:P07864 intact:EBI-12549378|ensembl:ENSP00000472769|uniprotkb:Q7L5R2|uniprotkb:Q9BPY7 intact:EBI-21716174|uniprotkb:D3DQY4|uniprotkb:Q6GSG8|uniprotkb:Q7Z7J4|ensembl:ENSP00000280704|ensembl:ENSP00000437783 psi-mi:tx101_human(display_long)|uniprotkb:TEX101(gene name)|psi-mi:TEX101(display_short)|uniprotkb:Cell surface receptor NYD-SP8(gene name synonym)|uniprotkb:SGRG(gene name synonym)|uniprotkb:Scleroderma-associated autoantigen(gene name synonym)|uniprotkb:Spermatogenesis-related gene protein(gene name synonym)|uniprotkb:UNQ867/PRO1884(orf name) psi-mi:ldhc_human(display_long)|uniprotkb:Cancer/testis antigen 32(gene name synonym)|uniprotkb:LDH testis subunit(gene name synonym)|uniprotkb:LDH-X(gene name synonym)|uniprotkb:LDHC(gene name)|psi-mi:LDHC(display_short)|uniprotkb:LDH3(gene name synonym)|uniprotkb:LDHX(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Schiza et al. (2018) imex:IM-28077|pubmed:30097533 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-25505396|imex:IM-28077-7 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000131126(gene)|ensembl:ENST00000598265(transcript)|go:"GO:0001669"(acrosomal vesicle)|go:"GO:0002080"(acrosomal membrane)|go:"GO:0005576"(extracellular region)|go:"GO:0005886"(plasma membrane)|go:"GO:0007339"(binding of sperm to zona pellucida)|go:"GO:0009566"(fertilization)|go:"GO:0030317"(flagellated sperm motility)|go:"GO:0044853"(plasma membrane raft)|go:"GO:0046658"(anchored component of plasma membrane)|go:"GO:1901317"(regulation of flagellated sperm motility)|interpro:IPR016054(Ly-6 antigen / uPA receptor -like)|rcsb pdb:7BPR|reactome:R-HSA-163125|refseq:NP_001123483.1|refseq:NP_113639.4 refseq:NP_002292.1|refseq:NP_059144.1|go:"GO:0030317"(flagellated sperm motility)|go:"GO:0031514"(motile cilium)|go:"GO:0070062"(extracellular exosome)|interpro:IPR001236(Lactate/malate dehydrogenase)|interpro:IPR001557(L-lactate/malate dehydrogenase)|interpro:IPR011304(L-lactate dehydrogenase)|interpro:IPR015955(Lactate dehydrogenase/glycoside hydrolase, family 4, C-terminal)|interpro:IPR018177|interpro:IPR022383|interpro:IPR036291|reactome:R-HSA-70268|ensembl:ENSG00000166796(gene)|ensembl:ENST00000280704(transcript)|ensembl:ENST00000541669(transcript)|go:"GO:0004459"(L-lactate dehydrogenase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0005975"(carbohydrate metabolic process)|go:"GO:0006754"(ATP biosynthetic process)|go:"GO:0019244"(lactate biosynthetic process from pyruvate)|go:"GO:0019516"(lactate oxidation) - - - comment:"Proteins significantly enriched by immunoprecipitation with 34ED556 (T1) anti-TEX101 antibody in human sperm cells from pre-vasectomy semen samples."|figure legend:Fig. 2B, supplemental Table S6|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-spermatozoa)|taxid:9606(Homo sapiens) - 2020/03/24 2020/04/07 rogid:ZE4tXTFi7lUCcIbCL4KHzY3a6xM9606 rogid:Q8SOlZeihuMeWgII7Thdv8wSwn09606 rigid:TX1oljMyfkimcULEvhCJR/BRAW4 false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9BY14 uniprotkb:P04279 intact:EBI-12549378|ensembl:ENSP00000472769|uniprotkb:Q7L5R2|uniprotkb:Q9BPY7 intact:EBI-953955|ensembl:ENSP00000361867|uniprotkb:Q6X4I9|uniprotkb:Q6Y809|uniprotkb:Q6Y822|uniprotkb:Q6Y823|uniprotkb:Q86U64|uniprotkb:Q96QM3|uniprotkb:Q53ZV0|uniprotkb:Q53ZV1|uniprotkb:Q53ZV2 psi-mi:tx101_human(display_long)|uniprotkb:TEX101(gene name)|psi-mi:TEX101(display_short)|uniprotkb:Cell surface receptor NYD-SP8(gene name synonym)|uniprotkb:SGRG(gene name synonym)|uniprotkb:Scleroderma-associated autoantigen(gene name synonym)|uniprotkb:Spermatogenesis-related gene protein(gene name synonym)|uniprotkb:UNQ867/PRO1884(orf name) psi-mi:semg1_human(display_long)|uniprotkb:Semenogelin I(gene name synonym)|uniprotkb:SEMG1(gene name)|psi-mi:SEMG1(display_short)|uniprotkb:SEMG(gene name synonym)|uniprotkb:Cancer/testis antigen 103(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Schiza et al. (2018) imex:IM-28077|pubmed:30097533 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-25505396|imex:IM-28077-7 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000131126(gene)|ensembl:ENST00000598265(transcript)|go:"GO:0001669"(acrosomal vesicle)|go:"GO:0002080"(acrosomal membrane)|go:"GO:0005576"(extracellular region)|go:"GO:0005886"(plasma membrane)|go:"GO:0007339"(binding of sperm to zona pellucida)|go:"GO:0009566"(fertilization)|go:"GO:0030317"(flagellated sperm motility)|go:"GO:0044853"(plasma membrane raft)|go:"GO:0046658"(anchored component of plasma membrane)|go:"GO:1901317"(regulation of flagellated sperm motility)|interpro:IPR016054(Ly-6 antigen / uPA receptor -like)|rcsb pdb:7BPR|reactome:R-HSA-163125|refseq:NP_001123483.1|refseq:NP_113639.4 ensembl:ENSG00000124233(gene)|ensembl:ENST00000372781(transcript)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0005634"(nucleus)|go:"GO:0007320"(insemination)|go:"GO:0008270"(zinc ion binding)|go:"GO:0019731"(antibacterial humoral response)|go:"GO:0031640"(killing of cells of another organism)|go:"GO:0032991"(protein-containing complex)|go:"GO:0048240"(sperm capacitation)|go:"GO:0050817"(coagulation)|go:"GO:0061844"(antimicrobial humoral immune response mediated by antimicrobial peptide)|go:"GO:0070062"(extracellular exosome)|go:"GO:1900005"(positive regulation of serine-type endopeptidase activity)|go:"GO:1901318"(negative regulation of flagellated sperm motility)|interpro:IPR008836(Semenogelin)|mint:P04279|reactome:R-HSA-6803157|reactome:R-HSA-977225|go:"GO:0090281"(negative regulation of calcium ion import)|refseq:NP_002998.1 - - - comment:"Proteins significantly enriched by immunoprecipitation with 34ED556 (T1) anti-TEX101 antibody in human sperm cells from pre-vasectomy semen samples."|figure legend:Fig. 2B, supplemental Table S6|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-spermatozoa)|taxid:9606(Homo sapiens) - 2020/03/24 2020/04/07 rogid:ZE4tXTFi7lUCcIbCL4KHzY3a6xM9606 rogid:64nkdlFGdnz3KDB7rkGYOQ5l+uQ9606 rigid:TX1oljMyfkimcULEvhCJR/BRAW4 false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9BY14 uniprotkb:P14625 intact:EBI-12549378|ensembl:ENSP00000472769|uniprotkb:Q7L5R2|uniprotkb:Q9BPY7 intact:EBI-359129|uniprotkb:Q96A97|ensembl:ENSP00000299767 psi-mi:tx101_human(display_long)|uniprotkb:TEX101(gene name)|psi-mi:TEX101(display_short)|uniprotkb:Cell surface receptor NYD-SP8(gene name synonym)|uniprotkb:SGRG(gene name synonym)|uniprotkb:Scleroderma-associated autoantigen(gene name synonym)|uniprotkb:Spermatogenesis-related gene protein(gene name synonym)|uniprotkb:UNQ867/PRO1884(orf name) psi-mi:enpl_human(display_long)|uniprotkb:HSP90B1(gene name)|psi-mi:HSP90B1(display_short)|uniprotkb:TRA1(gene name synonym)|uniprotkb:Heat shock protein 90 kDa beta member 1(gene name synonym)|uniprotkb:94 kDa glucose-regulated protein(gene name synonym)|uniprotkb:GRP94(gene name synonym)|uniprotkb:gp96 homolog(gene name synonym)|uniprotkb:Tumor rejection antigen 1(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Schiza et al. (2018) imex:IM-28077|pubmed:30097533 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-25505396|imex:IM-28077-7 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000131126(gene)|ensembl:ENST00000598265(transcript)|go:"GO:0001669"(acrosomal vesicle)|go:"GO:0002080"(acrosomal membrane)|go:"GO:0005576"(extracellular region)|go:"GO:0005886"(plasma membrane)|go:"GO:0007339"(binding of sperm to zona pellucida)|go:"GO:0009566"(fertilization)|go:"GO:0030317"(flagellated sperm motility)|go:"GO:0044853"(plasma membrane raft)|go:"GO:0046658"(anchored component of plasma membrane)|go:"GO:1901317"(regulation of flagellated sperm motility)|interpro:IPR016054(Ly-6 antigen / uPA receptor -like)|rcsb pdb:7BPR|reactome:R-HSA-163125|refseq:NP_001123483.1|refseq:NP_113639.4 refseq:NP_003290.1|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043666"(regulation of phosphoprotein phosphatase activity)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0050750"(low-density lipoprotein particle receptor binding)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0051208"(sequestering of calcium ion)|go:"GO:0062023"(collagen-containing extracellular matrix)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071318"(cellular response to ATP)|go:"GO:0071682"(endocytic vesicle lumen)|interpro:IPR001404(Heat shock protein Hsp90)|interpro:IPR003594(ATP-binding region, ATPase-like)|interpro:IPR019805|interpro:IPR020568|interpro:IPR020575|interpro:IPR036890|interpro:IPR037196|mint:P14625|rcsb pdb:4NH9|reactome:R-HSA-1679131|reactome:R-HSA-3000480|reactome:R-HSA-381183|reactome:R-HSA-381426|reactome:R-HSA-6785807|reactome:R-HSA-8957275|ensembl:ENSG00000166598(gene)|ensembl:ENST00000299767(transcript)|go:"GO:0001666"(response to hypoxia)|go:"GO:0003723"(RNA binding)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005634"(nucleus)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005788"(endoplasmic reticulum lumen)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005925"(focal adhesion)|go:"GO:0006457"(protein folding)|go:"GO:0015031"(protein transport)|go:"GO:0016020"(membrane)|go:"GO:0019903"(protein phosphatase binding)|go:"GO:0030433"(ubiquitin-dependent ERAD pathway)|go:"GO:0030496"(midbody)|go:"GO:0030970"(retrograde protein transport, ER to cytosol)|go:"GO:0031247"(actin rod assembly)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033018"(sarcoplasmic reticulum lumen)|go:"GO:0034663"(endoplasmic reticulum chaperone complex)|go:"GO:0034975"(protein folding in endoplasmic reticulum)|go:"GO:0034976"(response to endoplasmic reticulum stress)|go:"GO:0042470"(melanosome)|dip:DIP-36060N - - - comment:"Proteins significantly enriched by immunoprecipitation with 34ED556 (T1) anti-TEX101 antibody in human sperm cells from pre-vasectomy semen samples."|figure legend:Fig. 2B, supplemental Table S6|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-spermatozoa)|taxid:9606(Homo sapiens) - 2020/03/24 2020/04/07 rogid:ZE4tXTFi7lUCcIbCL4KHzY3a6xM9606 rogid:m5CdlplqVyMUWYe75aKDuMzztMY9606 rigid:TX1oljMyfkimcULEvhCJR/BRAW4 false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9BY14 uniprotkb:P05107 intact:EBI-12549378|ensembl:ENSP00000472769|uniprotkb:Q7L5R2|uniprotkb:Q9BPY7 intact:EBI-300173|ensembl:ENSP00000303242|ensembl:ENSP00000347279|ensembl:ENSP00000380948|ensembl:ENSP00000380950|ensembl:ENSP00000380955|uniprotkb:Q16418|uniprotkb:B3KTS8|uniprotkb:Q53HS5|uniprotkb:Q9UD72|uniprotkb:D3DSM1 psi-mi:tx101_human(display_long)|uniprotkb:TEX101(gene name)|psi-mi:TEX101(display_short)|uniprotkb:Cell surface receptor NYD-SP8(gene name synonym)|uniprotkb:SGRG(gene name synonym)|uniprotkb:Scleroderma-associated autoantigen(gene name synonym)|uniprotkb:Spermatogenesis-related gene protein(gene name synonym)|uniprotkb:UNQ867/PRO1884(orf name) psi-mi:itb2_human(display_long)|uniprotkb:ITGB2(gene name)|psi-mi:ITGB2(display_short)|uniprotkb:CD18(gene name synonym)|uniprotkb:Cell surface adhesion glycoproteins LFA-1/CR3/p150,95 subunit beta(gene name synonym)|uniprotkb:Complement receptor C3 subunit beta(gene name synonym)|uniprotkb:MFI7(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Schiza et al. (2018) imex:IM-28077|pubmed:30097533 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-25505396|imex:IM-28077-7 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000131126(gene)|ensembl:ENST00000598265(transcript)|go:"GO:0001669"(acrosomal vesicle)|go:"GO:0002080"(acrosomal membrane)|go:"GO:0005576"(extracellular region)|go:"GO:0005886"(plasma membrane)|go:"GO:0007339"(binding of sperm to zona pellucida)|go:"GO:0009566"(fertilization)|go:"GO:0030317"(flagellated sperm motility)|go:"GO:0044853"(plasma membrane raft)|go:"GO:0046658"(anchored component of plasma membrane)|go:"GO:1901317"(regulation of flagellated sperm motility)|interpro:IPR016054(Ly-6 antigen / uPA receptor -like)|rcsb pdb:7BPR|reactome:R-HSA-163125|refseq:NP_001123483.1|refseq:NP_113639.4 go:"GO:0006915"(apoptotic process)|go:"GO:0006954"(inflammatory response)|go:"GO:0007155"(cell adhesion)|go:"GO:0007159"(leukocyte cell-cell adhesion)|go:"GO:0007160"(cell-matrix adhesion)|go:"GO:0007229"(integrin-mediated signaling pathway)|go:"GO:0007267"(cell-cell signaling)|go:"GO:0008305"(integrin complex)|go:"GO:0008360"(regulation of cell shape)|go:"GO:0009897"(external side of plasma membrane)|go:"GO:0009986"(cell surface)|go:"GO:0016020"(membrane)|go:"GO:0016477"(cell migration)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030369"(ICAM-3 receptor activity)|go:"GO:0030593"(neutrophil chemotaxis)|go:"GO:0031072"(heat shock protein binding)|go:"GO:0031623"(receptor internalization)|go:"GO:0032930"(positive regulation of superoxide anion generation)|go:"GO:0033627"(cell adhesion mediated by integrin)|go:"GO:0034113"(heterotypic cell-cell adhesion)|go:"GO:0034687"(integrin alphaL-beta2 complex)|go:"GO:0034688"(integrin alphaM-beta2 complex)|go:"GO:0034689"(integrin alphaX-beta2 complex)|go:"GO:0035579"(specific granule membrane)|go:"GO:0035987"(endodermal cell differentiation)|go:"GO:0043113"(receptor clustering)|ensembl:ENSG00000160255(gene)|ensembl:ENST00000302347(transcript)|ensembl:ENST00000355153(transcript)|ensembl:ENST00000397850(transcript)|ensembl:ENST00000397852(transcript)|ensembl:ENST00000397857(transcript)|go:"GO:0001540"(amyloid-beta binding)|go:"GO:0001774"(microglial cell activation)|go:"GO:0001851"(complement component C3b binding)|go:"GO:0005178"(integrin binding)|go:"GO:0005886"(plasma membrane)|go:"GO:0005925"(focal adhesion)|go:"GO:0006898"(receptor-mediated endocytosis)|go:"GO:0006911"(phagocytosis, engulfment)|go:"GO:0097242"(amyloid-beta clearance)|go:"GO:0098609"(cell-cell adhesion)|go:"GO:0098742"(cell-cell adhesion via plasma-membrane adhesion molecules)|go:"GO:0101003"(ficolin-1-rich granule membrane)|go:"GO:1901216"(positive regulation of neuron death)|go:"GO:0043235"(receptor complex)|go:"GO:0043315"(positive regulation of neutrophil degranulation)|go:"GO:0044853"(plasma membrane raft)|go:"GO:1903561"(extracellular vesicle)|go:"GO:1904996"(positive regulation of leukocyte adhesion to vascular endothelial cell)|go:"GO:0045963"(negative regulation of dopamine metabolic process)|go:"GO:1990266"(neutrophil migration)|go:"GO:2000363"(positive regulation of prostaglandin-E synthase activity)|interpro:IPR002369(Integrin beta subunit, N-terminal)|interpro:IPR012896(Integrin beta subunit, tail)|interpro:IPR014836(Integrin beta subunit, cytoplasmic)|interpro:IPR015439(Integrin beta-2 subunit, C-terminal)|interpro:IPR015812(Integrin beta subunit)|interpro:IPR016201(Plexin-like fold)|interpro:IPR032695|interpro:IPR033760|interpro:IPR036349|go:"GO:0046872"(metal ion binding)|interpro:IPR036465|go:"GO:0050730"(regulation of peptidyl-tyrosine phosphorylation)|mint:P05107|rcsb pdb:1JX3|rcsb pdb:1L3Y|rcsb pdb:1YUK|go:"GO:0050839"(cell adhesion molecule binding)|rcsb pdb:2JF1|go:"GO:0070062"(extracellular exosome)|rcsb pdb:2P26|rcsb pdb:2P28|rcsb pdb:2V7D|rcsb pdb:3K6S|rcsb pdb:3K71|rcsb pdb:3K72|go:"GO:0070821"(tertiary granule membrane)|rcsb pdb:4NEH|rcsb pdb:4NEN|go:"GO:0071404"(cellular response to low-density lipoprotein particle stimulus)|go:"GO:0090314"(positive regulation of protein targeting to membrane)|rcsb pdb:5E6R|rcsb pdb:5E6S|rcsb pdb:5E6U|rcsb pdb:5E6V|rcsb pdb:5E6W|rcsb pdb:5E6X|rcsb pdb:5ES4|rcsb pdb:5XR1|rcsb pdb:5ZAZ|reactome:R-HSA-166016|reactome:R-HSA-198933|reactome:R-HSA-202733|reactome:R-HSA-216083|reactome:R-HSA-6785807|reactome:R-HSA-6798695|refseq:NP_000202.3|refseq:NP_001120963.2|refseq:NP_001290167.1|dip:DIP-478N - - - comment:"Proteins significantly enriched by immunoprecipitation with 34ED556 (T1) anti-TEX101 antibody in human sperm cells from pre-vasectomy semen samples."|figure legend:Fig. 2B, supplemental Table S6|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-spermatozoa)|taxid:9606(Homo sapiens) - 2020/03/24 2020/04/07 rogid:ZE4tXTFi7lUCcIbCL4KHzY3a6xM9606 rogid:aaycm8Q/rmu01cs20dw399oJjFE9606 rigid:TX1oljMyfkimcULEvhCJR/BRAW4 false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9BY14 uniprotkb:P11215 intact:EBI-12549378|ensembl:ENSP00000472769|uniprotkb:Q7L5R2|uniprotkb:Q9BPY7 intact:EBI-2568251|uniprotkb:Q4VAK0|uniprotkb:Q4VAK2|ensembl:ENSP00000441691|uniprotkb:Q4VAK1 psi-mi:tx101_human(display_long)|uniprotkb:TEX101(gene name)|psi-mi:TEX101(display_short)|uniprotkb:Cell surface receptor NYD-SP8(gene name synonym)|uniprotkb:SGRG(gene name synonym)|uniprotkb:Scleroderma-associated autoantigen(gene name synonym)|uniprotkb:Spermatogenesis-related gene protein(gene name synonym)|uniprotkb:UNQ867/PRO1884(orf name) psi-mi:itam_human(display_long)|uniprotkb:ITGAM(gene name)|psi-mi:ITGAM(display_short)|uniprotkb:CD11B(gene name synonym)|uniprotkb:CR3A(gene name synonym)|uniprotkb:Cell surface glycoprotein MAC-1 subunit alpha(gene name synonym)|uniprotkb:CR-3 alpha chain(gene name synonym)|uniprotkb:Leukocyte adhesion receptor MO1(gene name synonym)|uniprotkb:Neutrophil adherence receptor(gene name synonym)|uniprotkb:CD11 antigen-like family member B(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Schiza et al. (2018) imex:IM-28077|pubmed:30097533 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-25505396|imex:IM-28077-7 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000131126(gene)|ensembl:ENST00000598265(transcript)|go:"GO:0001669"(acrosomal vesicle)|go:"GO:0002080"(acrosomal membrane)|go:"GO:0005576"(extracellular region)|go:"GO:0005886"(plasma membrane)|go:"GO:0007339"(binding of sperm to zona pellucida)|go:"GO:0009566"(fertilization)|go:"GO:0030317"(flagellated sperm motility)|go:"GO:0044853"(plasma membrane raft)|go:"GO:0046658"(anchored component of plasma membrane)|go:"GO:1901317"(regulation of flagellated sperm motility)|interpro:IPR016054(Ly-6 antigen / uPA receptor -like)|rcsb pdb:7BPR|reactome:R-HSA-163125|refseq:NP_001123483.1|refseq:NP_113639.4 refseq:NP_000623.2|refseq:NP_001139280.1|ensembl:ENSG00000169896(gene)|ensembl:ENST00000544665(transcript)|go:"GO:0001540"(amyloid-beta binding)|go:"GO:0001774"(microglial cell activation)|go:"GO:0001851"(complement component C3b binding)|go:"GO:0005178"(integrin binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005886"(plasma membrane)|go:"GO:0006898"(receptor-mediated endocytosis)|go:"GO:0006911"(phagocytosis, engulfment)|go:"GO:0007155"(cell adhesion)|go:"GO:0007229"(integrin-mediated signaling pathway)|go:"GO:0008305"(integrin complex)|go:"GO:0009986"(cell surface)|go:"GO:0010668"(ectodermal cell differentiation)|go:"GO:0030900"(forebrain development)|go:"GO:0031072"(heat shock protein binding)|go:"GO:0032930"(positive regulation of superoxide anion generation)|go:"GO:0034688"(integrin alphaM-beta2 complex)|go:"GO:0035579"(specific granule membrane)|go:"GO:0038024"(cargo receptor activity)|go:"GO:0043315"(positive regulation of neutrophil degranulation)|go:"GO:0044853"(plasma membrane raft)|go:"GO:0045087"(innate immune response)|go:"GO:0009897"(external side of plasma membrane)|go:"GO:0045963"(negative regulation of dopamine metabolic process)|go:"GO:0046872"(metal ion binding)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070821"(tertiary granule membrane)|go:"GO:0090314"(positive regulation of protein targeting to membrane)|go:"GO:0097190"(apoptotic signaling pathway)|go:"GO:0097242"(amyloid-beta clearance)|go:"GO:0098742"(cell-cell adhesion via plasma-membrane adhesion molecules)|go:"GO:0110090"(positive regulation of hippocampal neuron apoptotic process)|go:"GO:0150062"(complement-mediated synapse pruning)|go:"GO:0150064"(vertebrate eye-specific patterning)|go:"GO:1901216"(positive regulation of neuron death)|go:"GO:1904151"(positive regulation of microglial cell mediated cytotoxicity)|go:"GO:1905114"(cell surface receptor signaling pathway involved in cell-cell signaling)|go:"GO:2000363"(positive regulation of prostaglandin-E synthase activity)|interpro:IPR000413(Integrins alpha chain)|interpro:IPR002035(von Willebrand factor, type A)|interpro:IPR013517(FG-GAP)|interpro:IPR013519(Integrin alpha beta-propellor)|interpro:IPR013649(Integrin alpha-2)|interpro:IPR018184|interpro:IPR028994|interpro:IPR032695|interpro:IPR036465|rcsb pdb:1A8X|rcsb pdb:1BHO|rcsb pdb:1BHQ|rcsb pdb:1IDN|rcsb pdb:1IDO|rcsb pdb:1JLM|rcsb pdb:1M1U|rcsb pdb:1MF7|rcsb pdb:1N9Z|rcsb pdb:1NA5|rcsb pdb:2LKE|rcsb pdb:2LKJ|rcsb pdb:3Q3G|rcsb pdb:3QA3|rcsb pdb:4M76|rcsb pdb:4XW2|rcsb pdb:6RHW|reactome:R-HSA-166016|reactome:R-HSA-202733|reactome:R-HSA-216083|reactome:R-HSA-6785807|reactome:R-HSA-6798695 - - - comment:"Proteins significantly enriched by immunoprecipitation with 34ED556 (T1) anti-TEX101 antibody in human sperm cells from pre-vasectomy semen samples."|figure legend:Fig. 2B, supplemental Table S6|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-spermatozoa)|taxid:9606(Homo sapiens) - 2020/03/24 2020/04/07 rogid:ZE4tXTFi7lUCcIbCL4KHzY3a6xM9606 rogid:LdazC8w25LRfb+vgr/kGcKmIkYo9606 rigid:TX1oljMyfkimcULEvhCJR/BRAW4 false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9BY14 uniprotkb:P55072 intact:EBI-12549378|ensembl:ENSP00000472769|uniprotkb:Q7L5R2|uniprotkb:Q9BPY7 intact:EBI-355164|uniprotkb:Q969G7|uniprotkb:Q9UCD5|uniprotkb:B2R5T8|uniprotkb:Q0V924|uniprotkb:Q2TAI5|intact:EBI-1046421|ensembl:ENSP00000351777 psi-mi:tx101_human(display_long)|uniprotkb:TEX101(gene name)|psi-mi:TEX101(display_short)|uniprotkb:Cell surface receptor NYD-SP8(gene name synonym)|uniprotkb:SGRG(gene name synonym)|uniprotkb:Scleroderma-associated autoantigen(gene name synonym)|uniprotkb:Spermatogenesis-related gene protein(gene name synonym)|uniprotkb:UNQ867/PRO1884(orf name) psi-mi:tera_human(display_long)|uniprotkb:VCP(gene name)|psi-mi:VCP(display_short)|uniprotkb:"15S Mg(2+)-ATPase p97 subunit"(gene name synonym)|uniprotkb:Valosin-containing protein(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Schiza et al. (2018) imex:IM-28077|pubmed:30097533 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-25505396|imex:IM-28077-7 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000131126(gene)|ensembl:ENST00000598265(transcript)|go:"GO:0001669"(acrosomal vesicle)|go:"GO:0002080"(acrosomal membrane)|go:"GO:0005576"(extracellular region)|go:"GO:0005886"(plasma membrane)|go:"GO:0007339"(binding of sperm to zona pellucida)|go:"GO:0009566"(fertilization)|go:"GO:0030317"(flagellated sperm motility)|go:"GO:0044853"(plasma membrane raft)|go:"GO:0046658"(anchored component of plasma membrane)|go:"GO:1901317"(regulation of flagellated sperm motility)|interpro:IPR016054(Ly-6 antigen / uPA receptor -like)|rcsb pdb:7BPR|reactome:R-HSA-163125|refseq:NP_001123483.1|refseq:NP_113639.4 refseq:NP_009057.1|rcsb pdb:7BPA|rcsb pdb:7BPB|rcsb pdb:7JY5|reactome:R-HSA-110320|reactome:R-HSA-3371511|reactome:R-HSA-382556|reactome:R-HSA-532668|reactome:R-HSA-5358346|reactome:R-HSA-5362768|reactome:R-HSA-5678895|reactome:R-HSA-5689877|reactome:R-HSA-5689896|reactome:R-HSA-6798695|reactome:R-HSA-8866654|reactome:R-HSA-8876725|reactome:R-HSA-9013407|reactome:R-HSA-9646399|reactome:R-HSA-9678110|reactome:R-HSA-9694614|rcsb pdb:7BP9|go:"GO:0032510"(endosome to lysosome transport via multivesicular body sorting pathway)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034098"(VCP-NPL4-UFD1 AAA ATPase complex)|go:"GO:0034605"(cellular response to heat)|go:"GO:0034774"(secretory granule lumen)|go:"GO:0035578"(azurophil granule lumen)|go:"GO:0035617"(stress granule disassembly)|go:"GO:0035800"(deubiquitinase activator activity)|go:"GO:0035861"(site of double-strand break)|go:"GO:0036297"(interstrand cross-link repair)|go:"GO:0036435"(K48-linked polyubiquitin modification-dependent protein binding)|go:"GO:0036503"(ERAD pathway)|go:"GO:0036513"(Derlin-1 retrotranslocation complex)|go:"GO:0042288"(MHC class I protein binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0032436"(positive regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0043531"(ADP binding)|go:"GO:0044389"(ubiquitin-like protein ligase binding)|go:"GO:0045184"(establishment of protein localization)|go:"GO:0045732"(positive regulation of protein catabolic process)|go:"GO:0045879"(negative regulation of smoothened signaling pathway)|go:"GO:0046034"(ATP metabolic process)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0050807"(regulation of synapse organization)|go:"GO:0051228"(mitotic spindle disassembly)|go:"GO:0061857"(endoplasmic reticulum stress-induced pre-emptive quality control)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070842"(aggresome assembly)|go:"GO:0071712"(ER-associated misfolded protein catabolic process)|go:"GO:0072389"(flavin adenine dinucleotide catabolic process)|go:"GO:0090263"(positive regulation of canonical Wnt signaling pathway)|go:"GO:0097352"(autophagosome maturation)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0106300"(protein-DNA covalent cross-linking repair)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|go:"GO:1903006"(positive regulation of protein K63-linked deubiquitination)|go:"GO:1903007"(positive regulation of Lys63-specific deubiquitinase activity)|go:"GO:1903715"(regulation of aerobic respiration)|go:"GO:1903843"(cellular response to arsenite ion)|go:"GO:1903862"(positive regulation of oxidative phosphorylation)|go:"GO:1904288"(BAT3 complex binding)|go:"GO:1904813"(ficolin-1-rich granule lumen)|go:"GO:1904949"(ATPase complex)|go:"GO:1905634"(regulation of protein localization to chromatin)|go:"GO:1990381"(ubiquitin-specific protease binding)|go:"GO:1990730"(VCP-NSFL1C complex)|go:"GO:2001171"(positive regulation of ATP biosynthetic process)|interpro:IPR003338(AAA ATPase VAT, N-terminal)|interpro:IPR003593(AAA+ ATPase, core)|ensembl:ENSG00000165280(gene)|ensembl:ENST00000358901(transcript)|go:"GO:0000502"(proteasome complex)|go:"GO:0003723"(RNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005811"(lipid droplet)|go:"GO:0005829"(cytosol)|go:"GO:0006281"(DNA repair)|go:"GO:0006302"(double-strand break repair)|go:"GO:0006734"(NADH metabolic process)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0006914"(autophagy)|go:"GO:0006919"(activation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0008289"(lipid binding)|go:"GO:0010494"(cytoplasmic stress granule)|go:"GO:0010498"(proteasomal protein catabolic process)|go:"GO:0010918"(positive regulation of mitochondrial membrane potential)|go:"GO:0016236"(macroautophagy)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0019079"(viral genome replication)|go:"GO:0019903"(protein phosphatase binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0019985"(translesion synthesis)|go:"GO:0030433"(ubiquitin-dependent ERAD pathway)|go:"GO:0030968"(endoplasmic reticulum unfolded protein response)|go:"GO:0030970"(retrograde protein transport, ER to cytosol)|go:"GO:0031334"(positive regulation of protein-containing complex assembly)|go:"GO:0031593"(polyubiquitin modification-dependent protein binding)|go:"GO:0031625"(ubiquitin protein ligase binding)|interpro:IPR003959(AAA ATPase, core)|interpro:IPR003960(AAA ATPase, conserved site)|interpro:IPR004201(Cell division protein 48, CDC48, domain 2)|interpro:IPR005938(AAA ATPase, CDC48)|interpro:IPR009010(Aspartate decarboxylase-like fold)|interpro:IPR015415(Vps4 oligomerisation, C-terminal)|interpro:IPR027417|interpro:IPR029067|interpro:IPR041569|mint:P55072|rcsb pdb:3EBB|rcsb pdb:3HU1|rcsb pdb:3HU2|rcsb pdb:3HU3|rcsb pdb:3QC8|rcsb pdb:3QQ7|rcsb pdb:3QQ8|rcsb pdb:3QWZ|rcsb pdb:3TIW|rcsb pdb:4KDI|rcsb pdb:4KDL|rcsb pdb:4KLN|rcsb pdb:4KO8|rcsb pdb:4KOD|rcsb pdb:4P0A|rcsb pdb:5B6C|rcsb pdb:5C18|rcsb pdb:5C19|rcsb pdb:5C1A|rcsb pdb:5C1B|rcsb pdb:5DYG|rcsb pdb:5DYI|rcsb pdb:5EPP|rcsb pdb:5FTJ|rcsb pdb:5FTK|rcsb pdb:5FTL|rcsb pdb:5FTM|rcsb pdb:5FTN|rcsb pdb:5GLF|rcsb pdb:5IFS|rcsb pdb:5IFW|rcsb pdb:5KIW|rcsb pdb:5KIY|rcsb pdb:5X4L|rcsb pdb:6G2V|rcsb pdb:6G2W|rcsb pdb:6G2X|rcsb pdb:6G2Y|rcsb pdb:6G2Z|rcsb pdb:6G30|rcsb pdb:6HD0|rcsb pdb:6MCK|rcsb pdb:7BP8|dip:DIP-33543N - - - comment:"Proteins significantly enriched by immunoprecipitation with 34ED556 (T1) anti-TEX101 antibody in human sperm cells from pre-vasectomy semen samples."|figure legend:Fig. 2B, supplemental Table S6|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-spermatozoa)|taxid:9606(Homo sapiens) - 2020/03/24 2020/04/07 rogid:ZE4tXTFi7lUCcIbCL4KHzY3a6xM9606 rogid:HrjDhdsDcgaf8HEbqqMjUqxPaEs9606 rigid:TX1oljMyfkimcULEvhCJR/BRAW4 false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9BY14 uniprotkb:Q9Y265 intact:EBI-12549378|ensembl:ENSP00000472769|uniprotkb:Q7L5R2|uniprotkb:Q9BPY7 intact:EBI-353675|uniprotkb:P82276|uniprotkb:Q1KMR0|uniprotkb:Q53HK5|uniprotkb:Q53HL7|uniprotkb:Q53Y27|uniprotkb:Q9BSX9|uniprotkb:B2R5S0|ensembl:ENSP00000318297|ensembl:ENSP00000494621 psi-mi:tx101_human(display_long)|uniprotkb:TEX101(gene name)|psi-mi:TEX101(display_short)|uniprotkb:Cell surface receptor NYD-SP8(gene name synonym)|uniprotkb:SGRG(gene name synonym)|uniprotkb:Scleroderma-associated autoantigen(gene name synonym)|uniprotkb:Spermatogenesis-related gene protein(gene name synonym)|uniprotkb:UNQ867/PRO1884(orf name) psi-mi:ruvb1_human(display_long)|uniprotkb:RUVBL1(gene name)|psi-mi:RUVBL1(display_short)|uniprotkb:NMP238(gene name synonym)|uniprotkb:TIP49(gene name synonym)|uniprotkb:TIP49A(gene name synonym)|uniprotkb:49 kDa TATA box-binding protein-interacting protein(gene name synonym)|uniprotkb:TIP49a(gene name synonym)|uniprotkb:Pontin 52(gene name synonym)|uniprotkb:Nuclear matrix protein 238(gene name synonym)|uniprotkb:54 kDa erythrocyte cytosolic protein(gene name synonym)|uniprotkb:INO80H(gene name synonym)|uniprotkb:TIP60-associated protein 54-alpha(gene name synonym)|uniprotkb:INO80 complex subunit H(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Schiza et al. (2018) imex:IM-28077|pubmed:30097533 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-25505396|imex:IM-28077-7 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000131126(gene)|ensembl:ENST00000598265(transcript)|go:"GO:0001669"(acrosomal vesicle)|go:"GO:0002080"(acrosomal membrane)|go:"GO:0005576"(extracellular region)|go:"GO:0005886"(plasma membrane)|go:"GO:0007339"(binding of sperm to zona pellucida)|go:"GO:0009566"(fertilization)|go:"GO:0030317"(flagellated sperm motility)|go:"GO:0044853"(plasma membrane raft)|go:"GO:0046658"(anchored component of plasma membrane)|go:"GO:1901317"(regulation of flagellated sperm motility)|interpro:IPR016054(Ly-6 antigen / uPA receptor -like)|rcsb pdb:7BPR|reactome:R-HSA-163125|refseq:NP_001123483.1|refseq:NP_113639.4 refseq:NP_003698.1|go:"GO:0016020"(membrane)|go:"GO:0016363"(nuclear matrix)|go:"GO:0016573"(histone acetylation)|go:"GO:0017025"(TBP-class protein binding)|go:"GO:0031011"(Ino80 complex)|go:"GO:0035267"(NuA4 histone acetyltransferase complex)|go:"GO:0040008"(regulation of growth)|go:"GO:0043139"(5'-3' DNA helicase activity)|go:"GO:0043531"(ADP binding)|go:"GO:0043967"(histone H4 acetylation)|go:"GO:0043968"(histone H2A acetylation)|go:"GO:0045296"(cadherin binding)|go:"GO:0051117"(ATPase binding)|go:"GO:0051301"(cell division)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071339"(MLL1 complex)|go:"GO:0090263"(positive regulation of canonical Wnt signaling pathway)|go:"GO:0097255"(R2TP complex)|go:"GO:0120293"(dynein axonemal particle)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|go:"GO:1904874"(positive regulation of telomerase RNA localization to Cajal body)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR010339(TIP49, C-terminal)|interpro:IPR027238|interpro:IPR027417|interpro:IPR037938|interpro:IPR041048|mint:Q9Y265|rcsb pdb:2C9O|rcsb pdb:2XSZ|rcsb pdb:5OAF|rcsb pdb:6FO1|rcsb pdb:6HTS|rcsb pdb:6IGM|rcsb pdb:6K0R|rcsb pdb:6QI8|rcsb pdb:6QI9|rcsb pdb:7AHO|reactome:R-HSA-171319|reactome:R-HSA-201722|reactome:R-HSA-3214847|reactome:R-HSA-5689603|reactome:R-HSA-5689880|reactome:R-HSA-5696394|reactome:R-HSA-606279|ensembl:ENSG00000175792(gene)|ensembl:ENSG00000284901(gene)|ensembl:ENST00000322623(transcript)|ensembl:ENST00000643444(transcript)|go:"GO:0000492"(box C/D snoRNP assembly)|go:"GO:0000812"(Swr1 complex)|go:"GO:0001094"(TFIID-class transcription factor complex binding)|go:"GO:0003678"(DNA helicase activity)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005815"(microtubule organizing center)|go:"GO:0005829"(cytosol)|go:"GO:0006281"(DNA repair)|go:"GO:0006310"(DNA recombination)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007049"(cell cycle)|go:"GO:0007283"(spermatogenesis)|refseq:NP_001306013.1|dip:DIP-29937N - - - comment:"Proteins significantly enriched by immunoprecipitation with 34ED556 (T1) anti-TEX101 antibody in human sperm cells from pre-vasectomy semen samples."|figure legend:Fig. 2B, supplemental Table S6|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-spermatozoa)|taxid:9606(Homo sapiens) - 2020/03/24 2020/04/07 rogid:ZE4tXTFi7lUCcIbCL4KHzY3a6xM9606 rogid:+FA/xQTUldQoWGRgad9U8vZpTHw9606 rigid:TX1oljMyfkimcULEvhCJR/BRAW4 false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9BY14 uniprotkb:P22695 intact:EBI-12549378|ensembl:ENSP00000472769|uniprotkb:Q7L5R2|uniprotkb:Q9BPY7 intact:EBI-1051424|uniprotkb:Q9BQ05|uniprotkb:B3KSN4|ensembl:ENSP00000268379 psi-mi:tx101_human(display_long)|uniprotkb:TEX101(gene name)|psi-mi:TEX101(display_short)|uniprotkb:Cell surface receptor NYD-SP8(gene name synonym)|uniprotkb:SGRG(gene name synonym)|uniprotkb:Scleroderma-associated autoantigen(gene name synonym)|uniprotkb:Spermatogenesis-related gene protein(gene name synonym)|uniprotkb:UNQ867/PRO1884(orf name) psi-mi:qcr2_human(display_long)|uniprotkb:Ubiquinol-cytochrome-c reductase complex core protein 2(gene name synonym)|uniprotkb:Core protein II(gene name synonym)|uniprotkb:Complex III subunit 2(gene name synonym)|uniprotkb:UQCRC2(gene name)|psi-mi:UQCRC2(display_short) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Schiza et al. (2018) imex:IM-28077|pubmed:30097533 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-25505396|imex:IM-28077-7 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000131126(gene)|ensembl:ENST00000598265(transcript)|go:"GO:0001669"(acrosomal vesicle)|go:"GO:0002080"(acrosomal membrane)|go:"GO:0005576"(extracellular region)|go:"GO:0005886"(plasma membrane)|go:"GO:0007339"(binding of sperm to zona pellucida)|go:"GO:0009566"(fertilization)|go:"GO:0030317"(flagellated sperm motility)|go:"GO:0044853"(plasma membrane raft)|go:"GO:0046658"(anchored component of plasma membrane)|go:"GO:1901317"(regulation of flagellated sperm motility)|interpro:IPR016054(Ly-6 antigen / uPA receptor -like)|rcsb pdb:7BPR|reactome:R-HSA-163125|refseq:NP_001123483.1|refseq:NP_113639.4 refseq:NP_003357.2|ensembl:ENSG00000140740(gene)|ensembl:ENST00000268379(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005750"(mitochondrial respiratory chain complex III)|go:"GO:0005751"(mitochondrial respiratory chain complex IV)|go:"GO:0006119"(oxidative phosphorylation)|go:"GO:0006508"(proteolysis)|go:"GO:0009060"(aerobic respiration)|go:"GO:0042493"|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0046872"(metal ion binding)|interpro:IPR001431(Peptidase M16, zinc-binding site)|interpro:IPR007863(Peptidase M16, C-terminal)|interpro:IPR011249(Metalloenzyme, LuxS/M16 peptidase-like, metal-binding)|interpro:IPR011765(Peptidase M16, N-terminal)|mint:P22695|rcsb pdb:5XTE|rcsb pdb:5XTH|rcsb pdb:5XTI|reactome:R-HSA-611105 - - - comment:"Proteins significantly enriched by immunoprecipitation with 34ED556 (T1) anti-TEX101 antibody in human sperm cells from pre-vasectomy semen samples."|figure legend:Fig. 2B, supplemental Table S6|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-spermatozoa)|taxid:9606(Homo sapiens) - 2020/03/24 2020/04/07 rogid:ZE4tXTFi7lUCcIbCL4KHzY3a6xM9606 rogid:++DmwaVpqzRyxFl7mh62L4ku4P09606 rigid:TX1oljMyfkimcULEvhCJR/BRAW4 false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9BY14 uniprotkb:Q00325 intact:EBI-12549378|ensembl:ENSP00000472769|uniprotkb:Q7L5R2|uniprotkb:Q9BPY7 intact:EBI-358549|uniprotkb:Q96A03|intact:EBI-28967087|ensembl:ENSP00000228318|ensembl:ENSP00000447310|uniprotkb:Q7Z7N7|uniprotkb:B3KS34 psi-mi:tx101_human(display_long)|uniprotkb:TEX101(gene name)|psi-mi:TEX101(display_short)|uniprotkb:Cell surface receptor NYD-SP8(gene name synonym)|uniprotkb:SGRG(gene name synonym)|uniprotkb:Scleroderma-associated autoantigen(gene name synonym)|uniprotkb:Spermatogenesis-related gene protein(gene name synonym)|uniprotkb:UNQ867/PRO1884(orf name) psi-mi:mpcp_human(display_long)|uniprotkb:SLC25A3(gene name)|psi-mi:SLC25A3(display_short)|uniprotkb:PHC(gene name synonym)|uniprotkb:OK/SW-cl.48(orf name)|uniprotkb:Phosphate transport protein(gene name synonym)|uniprotkb:Solute carrier family 25 member 3(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Schiza et al. (2018) imex:IM-28077|pubmed:30097533 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-25505396|imex:IM-28077-7 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000131126(gene)|ensembl:ENST00000598265(transcript)|go:"GO:0001669"(acrosomal vesicle)|go:"GO:0002080"(acrosomal membrane)|go:"GO:0005576"(extracellular region)|go:"GO:0005886"(plasma membrane)|go:"GO:0007339"(binding of sperm to zona pellucida)|go:"GO:0009566"(fertilization)|go:"GO:0030317"(flagellated sperm motility)|go:"GO:0044853"(plasma membrane raft)|go:"GO:0046658"(anchored component of plasma membrane)|go:"GO:1901317"(regulation of flagellated sperm motility)|interpro:IPR016054(Ly-6 antigen / uPA receptor -like)|rcsb pdb:7BPR|reactome:R-HSA-163125|refseq:NP_001123483.1|refseq:NP_113639.4 ensembl:ENST00000188376|ensembl:ENSP00000188376|ensembl:ENSP00000228318|ensembl:ENST00000401722|ensembl:ENSP00000383898|ensembl:ENST00000549338|ensembl:ENSP00000447740|ensembl:ENSP00000447310|ensembl:ENST00000552981|ensembl:ENSP00000448708|refseq:NP_002626.1|refseq:NP_005879.1|refseq:NP_998776.1|ensembl:ENSG00000075415(gene)|ensembl:ENST00000228318(transcript)|ensembl:ENST00000551917(transcript)|go:"GO:0005315"(inorganic phosphate transmembrane transporter activity)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0015317"("phosphate:proton symporter activity")|go:"GO:0016020"(membrane)|go:"GO:0031305"(integral component of mitochondrial inner membrane)|go:"GO:0035435"(phosphate ion transmembrane transport)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0070062"(extracellular exosome)|go:"GO:1990547"(mitochondrial phosphate ion transmembrane transport)|interpro:IPR018108|interpro:IPR023395|interpro:IPR044677|mint:Q00325 - - crc64:78714C85931B22D5 comment:"Proteins significantly enriched by immunoprecipitation with 34ED556 (T1) anti-TEX101 antibody in human sperm cells from pre-vasectomy semen samples."|figure legend:Fig. 2B, supplemental Table S6|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-spermatozoa)|taxid:9606(Homo sapiens) - 2020/03/24 2020/04/07 rogid:ZE4tXTFi7lUCcIbCL4KHzY3a6xM9606 rogid:f8THTDwNPyGowC9gCT9ZsizQ6qs9606 rigid:TX1oljMyfkimcULEvhCJR/BRAW4 false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9BY14 uniprotkb:Q86VP6 intact:EBI-12549378|ensembl:ENSP00000472769|uniprotkb:Q7L5R2|uniprotkb:Q9BPY7 intact:EBI-456077|uniprotkb:O94918|uniprotkb:Q6PIY4|uniprotkb:Q8NDJ4|uniprotkb:Q96JZ9|uniprotkb:Q96T19|uniprotkb:Q9BTC4|uniprotkb:Q9H0G2|uniprotkb:Q9P0H7|uniprotkb:Q9UF85|uniprotkb:B2RAU3|ensembl:ENSP00000442318 psi-mi:tx101_human(display_long)|uniprotkb:TEX101(gene name)|psi-mi:TEX101(display_short)|uniprotkb:Cell surface receptor NYD-SP8(gene name synonym)|uniprotkb:SGRG(gene name synonym)|uniprotkb:Scleroderma-associated autoantigen(gene name synonym)|uniprotkb:Spermatogenesis-related gene protein(gene name synonym)|uniprotkb:UNQ867/PRO1884(orf name) psi-mi:cand1_human(display_long)|uniprotkb:KIAA0829(gene name synonym)|uniprotkb:TIP120(gene name synonym)|uniprotkb:TIP120A(gene name synonym)|uniprotkb:Cullin-associated and neddylation-dissociated protein 1(gene name synonym)|uniprotkb:p120 CAND1(gene name synonym)|uniprotkb:TBP-interacting protein of 120 kDa A(gene name synonym)|uniprotkb:CAND1(gene name)|psi-mi:CAND1(display_short) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Schiza et al. (2018) imex:IM-28077|pubmed:30097533 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-25505396|imex:IM-28077-7 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000131126(gene)|ensembl:ENST00000598265(transcript)|go:"GO:0001669"(acrosomal vesicle)|go:"GO:0002080"(acrosomal membrane)|go:"GO:0005576"(extracellular region)|go:"GO:0005886"(plasma membrane)|go:"GO:0007339"(binding of sperm to zona pellucida)|go:"GO:0009566"(fertilization)|go:"GO:0030317"(flagellated sperm motility)|go:"GO:0044853"(plasma membrane raft)|go:"GO:0046658"(anchored component of plasma membrane)|go:"GO:1901317"(regulation of flagellated sperm motility)|interpro:IPR016054(Ly-6 antigen / uPA receptor -like)|rcsb pdb:7BPR|reactome:R-HSA-163125|refseq:NP_001123483.1|refseq:NP_113639.4 refseq:NP_060918.2|dip:DIP-31608N|ensembl:ENSG00000111530(gene)|ensembl:ENST00000545606(transcript)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0005576"(extracellular region)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0010265"(SCF complex assembly)|go:"GO:0016020"(membrane)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0017025"(TBP-class protein binding)|go:"GO:0030154"(cell differentiation)|go:"GO:0031461"(cullin-RING ubiquitin ligase complex)|go:"GO:0034774"(secretory granule lumen)|go:"GO:0043086"(negative regulation of catalytic activity)|go:"GO:0045899"(positive regulation of RNA polymerase II transcription preinitiation complex assembly)|go:"GO:0070062"(extracellular exosome)|go:"GO:1904813"(ficolin-1-rich granule lumen)|interpro:IPR013932("TATA-binding protein interacting (TIP20)")|interpro:IPR039852|mint:Q86VP6|rcsb pdb:1U6G|rcsb pdb:4A0C|reactome:R-HSA-6798695|reactome:R-HSA-8951664|reactome:R-HSA-917937|interpro:IPR016024(Armadillo-type fold) - - - comment:"Proteins significantly enriched by immunoprecipitation with 34ED556 (T1) anti-TEX101 antibody in human sperm cells from pre-vasectomy semen samples."|figure legend:Fig. 2B, supplemental Table S6|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-spermatozoa)|taxid:9606(Homo sapiens) - 2020/03/24 2020/04/07 rogid:ZE4tXTFi7lUCcIbCL4KHzY3a6xM9606 rogid:2lBY8xJXlGZL+xyo/dyB2WzuNqs9606 rigid:TX1oljMyfkimcULEvhCJR/BRAW4 false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9BY14 uniprotkb:P55084 intact:EBI-12549378|ensembl:ENSP00000472769|uniprotkb:Q7L5R2|uniprotkb:Q9BPY7 intact:EBI-356635|uniprotkb:Q9T2V8|uniprotkb:O14969|uniprotkb:Q53TA6|uniprotkb:Q96C77|uniprotkb:Q9H3F5|uniprotkb:B2RB16|intact:EBI-2948478|ensembl:ENSP00000325136|intact:EBI-8012123|intact:MINT-8395035|uniprotkb:B4E2W0 psi-mi:tx101_human(display_long)|uniprotkb:TEX101(gene name)|psi-mi:TEX101(display_short)|uniprotkb:Cell surface receptor NYD-SP8(gene name synonym)|uniprotkb:SGRG(gene name synonym)|uniprotkb:Scleroderma-associated autoantigen(gene name synonym)|uniprotkb:Spermatogenesis-related gene protein(gene name synonym)|uniprotkb:UNQ867/PRO1884(orf name) psi-mi:echb_human(display_long)|uniprotkb:HADHB(gene name)|psi-mi:HADHB(display_short)|uniprotkb:MSTP029(orf name)|uniprotkb:TP-beta(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Schiza et al. (2018) imex:IM-28077|pubmed:30097533 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-25505396|imex:IM-28077-7 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000131126(gene)|ensembl:ENST00000598265(transcript)|go:"GO:0001669"(acrosomal vesicle)|go:"GO:0002080"(acrosomal membrane)|go:"GO:0005576"(extracellular region)|go:"GO:0005886"(plasma membrane)|go:"GO:0007339"(binding of sperm to zona pellucida)|go:"GO:0009566"(fertilization)|go:"GO:0030317"(flagellated sperm motility)|go:"GO:0044853"(plasma membrane raft)|go:"GO:0046658"(anchored component of plasma membrane)|go:"GO:1901317"(regulation of flagellated sperm motility)|interpro:IPR016054(Ly-6 antigen / uPA receptor -like)|rcsb pdb:7BPR|reactome:R-HSA-163125|refseq:NP_001123483.1|refseq:NP_113639.4 refseq:NP_000174.1|ensembl:ENSG00000138029(gene)|ensembl:ENST00000317799(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0003857"(3-hydroxyacyl-CoA dehydrogenase activity)|go:"GO:0003988"(acetyl-CoA C-acyltransferase activity)|go:"GO:0004300"(enoyl-CoA hydratase activity)|go:"GO:0005739"(mitochondrion)|go:"GO:0005740"(mitochondrial envelope)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0006635"(fatty acid beta-oxidation)|go:"GO:0042645"(mitochondrial nucleoid)|go:"GO:0050633"(acetyl-CoA C-myristoyltransferase activity)|interpro:IPR002155(Thiolase)|interpro:IPR016039(Thiolase-like)|interpro:IPR020610|interpro:IPR020613|interpro:IPR020615|interpro:IPR020616|interpro:IPR020617|mint:P55084|rcsb pdb:5ZQZ|rcsb pdb:5ZRV|rcsb pdb:6DV2|reactome:R-HSA-1482798|reactome:R-HSA-77285|reactome:R-HSA-77288|reactome:R-HSA-77305|reactome:R-HSA-77310|reactome:R-HSA-77346|reactome:R-HSA-77348|reactome:R-HSA-77350|refseq:XP_011531105.1|refseq:NP_001268441.1|refseq:NP_001268442.1 - - - comment:"Proteins significantly enriched by immunoprecipitation with 34ED556 (T1) anti-TEX101 antibody in human sperm cells from pre-vasectomy semen samples."|figure legend:Fig. 2B, supplemental Table S6|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-spermatozoa)|taxid:9606(Homo sapiens) - 2020/03/24 2020/04/07 rogid:ZE4tXTFi7lUCcIbCL4KHzY3a6xM9606 rogid:4w0QYaw1wLyr5NJOKZ9naymK8kg9606 rigid:TX1oljMyfkimcULEvhCJR/BRAW4 false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9BY14 uniprotkb:P13473 intact:EBI-12549378|ensembl:ENSP00000472769|uniprotkb:Q7L5R2|uniprotkb:Q9BPY7 intact:EBI-2907154|uniprotkb:A8K4X5|uniprotkb:Q16641|uniprotkb:Q96J30|uniprotkb:Q99534|uniprotkb:Q9UD93|uniprotkb:D3DTF0|intact:EBI-4324646|uniprotkb:Q6Q3G8|ensembl:ENSP00000200639 psi-mi:tx101_human(display_long)|uniprotkb:TEX101(gene name)|psi-mi:TEX101(display_short)|uniprotkb:Cell surface receptor NYD-SP8(gene name synonym)|uniprotkb:SGRG(gene name synonym)|uniprotkb:Scleroderma-associated autoantigen(gene name synonym)|uniprotkb:Spermatogenesis-related gene protein(gene name synonym)|uniprotkb:UNQ867/PRO1884(orf name) psi-mi:lamp2_human(display_long)|uniprotkb:LAMP2(gene name)|psi-mi:LAMP2(display_short)|uniprotkb:CD107 antigen-like family member B(gene name synonym)|uniprotkb:LGP-96(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Schiza et al. (2018) imex:IM-28077|pubmed:30097533 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-25505396|imex:IM-28077-7 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000131126(gene)|ensembl:ENST00000598265(transcript)|go:"GO:0001669"(acrosomal vesicle)|go:"GO:0002080"(acrosomal membrane)|go:"GO:0005576"(extracellular region)|go:"GO:0005886"(plasma membrane)|go:"GO:0007339"(binding of sperm to zona pellucida)|go:"GO:0009566"(fertilization)|go:"GO:0030317"(flagellated sperm motility)|go:"GO:0044853"(plasma membrane raft)|go:"GO:0046658"(anchored component of plasma membrane)|go:"GO:1901317"(regulation of flagellated sperm motility)|interpro:IPR016054(Ly-6 antigen / uPA receptor -like)|rcsb pdb:7BPR|reactome:R-HSA-163125|refseq:NP_001123483.1|refseq:NP_113639.4 refseq:NP_002285.1|refseq:NP_054701.1|refseq:NP_001116078.1|ensembl:ENSG00000005893(gene)|ensembl:ENST00000200639(transcript)|go:"GO:0005615"(extracellular space)|go:"GO:0005764"(lysosome)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005770"(late endosome)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0005886"(plasma membrane)|go:"GO:0006605"(protein targeting)|go:"GO:0009267"(cellular response to starvation)|go:"GO:0016020"(membrane)|go:"GO:0017038"(protein import)|go:"GO:0019899"(enzyme binding)|go:"GO:0031088"(platelet dense granule membrane)|go:"GO:0031333"(negative regulation of protein-containing complex assembly)|go:"GO:0031647"(regulation of protein stability)|go:"GO:0031902"(late endosome membrane)|go:"GO:0035577"(azurophil granule membrane)|go:"GO:0043202"(lysosomal lumen)|go:"GO:0044754"(autolysosome)|go:"GO:0045121"(membrane raft)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0050821"(protein stabilization)|go:"GO:0061684"(chaperone-mediated autophagy)|go:"GO:0061740"(protein targeting to lysosome involved in chaperone-mediated autophagy)|go:"GO:0061742"(chaperone-mediated autophagy translocation complex)|go:"GO:0070062"(extracellular exosome)|go:"GO:0072594"(establishment of protein localization to organelle)|go:"GO:0097352"(autophagosome maturation)|go:"GO:0097637"(integral component of autophagosome membrane)|go:"GO:0101003"(ficolin-1-rich granule membrane)|go:"GO:1905146"(lysosomal protein catabolic process)|go:"GO:1990836"(lysosomal matrix)|interpro:IPR002000("Lysosome-associated membrane glycoprotein (Lamp)/CD68")|interpro:IPR018134|mint:P13473|rcsb pdb:2MOF|rcsb pdb:2MOM|reactome:R-HSA-114608|reactome:R-HSA-6798695|reactome:R-HSA-9613829 - - - comment:"Proteins significantly enriched by immunoprecipitation with 34ED556 (T1) anti-TEX101 antibody in human sperm cells from pre-vasectomy semen samples."|figure legend:Fig. 2B, supplemental Table S6|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-spermatozoa)|taxid:9606(Homo sapiens) - 2020/03/24 2020/04/07 rogid:ZE4tXTFi7lUCcIbCL4KHzY3a6xM9606 rogid:+s4K/qoL3PBwjATJmFDQtqcl/ZQ9606 rigid:TX1oljMyfkimcULEvhCJR/BRAW4 false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9BY14 uniprotkb:P10909 intact:EBI-12549378|ensembl:ENSP00000472769|uniprotkb:Q7L5R2|uniprotkb:Q9BPY7 intact:EBI-1104674|uniprotkb:B3KSE6|uniprotkb:P11380|uniprotkb:P11381|uniprotkb:Q5HYC1|uniprotkb:Q7Z5B9|uniprotkb:B2R9Q1|uniprotkb:Q2TU75|ensembl:ENSP00000315130|ensembl:ENSP00000385419|ensembl:ENSP00000429620 psi-mi:tx101_human(display_long)|uniprotkb:TEX101(gene name)|psi-mi:TEX101(display_short)|uniprotkb:Cell surface receptor NYD-SP8(gene name synonym)|uniprotkb:SGRG(gene name synonym)|uniprotkb:Scleroderma-associated autoantigen(gene name synonym)|uniprotkb:Spermatogenesis-related gene protein(gene name synonym)|uniprotkb:UNQ867/PRO1884(orf name) psi-mi:clus_human(display_long)|uniprotkb:CLU(gene name)|psi-mi:CLU(display_short)|uniprotkb:APOJ(gene name synonym)|uniprotkb:CLI(gene name synonym)|uniprotkb:KUB1(gene name synonym)|uniprotkb:Complement-associated protein SP-40,40(gene name synonym)|uniprotkb:Complement cytolysis inhibitor(gene name synonym)|uniprotkb:NA1/NA2(gene name synonym)|uniprotkb:Apolipoprotein J(gene name synonym)|uniprotkb:Testosterone-repressed prostate message 2(gene name synonym)|uniprotkb:Ku70-binding protein 1(gene name synonym)|uniprotkb:Aging-associated gene 4 protein(gene name synonym)|uniprotkb:AAG4(orf name)|uniprotkb:Sulfated glycoprotein 2(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Schiza et al. (2018) imex:IM-28077|pubmed:30097533 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-25505396|imex:IM-28077-7 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000131126(gene)|ensembl:ENST00000598265(transcript)|go:"GO:0001669"(acrosomal vesicle)|go:"GO:0002080"(acrosomal membrane)|go:"GO:0005576"(extracellular region)|go:"GO:0005886"(plasma membrane)|go:"GO:0007339"(binding of sperm to zona pellucida)|go:"GO:0009566"(fertilization)|go:"GO:0030317"(flagellated sperm motility)|go:"GO:0044853"(plasma membrane raft)|go:"GO:0046658"(anchored component of plasma membrane)|go:"GO:1901317"(regulation of flagellated sperm motility)|interpro:IPR016054(Ly-6 antigen / uPA receptor -like)|rcsb pdb:7BPR|reactome:R-HSA-163125|refseq:NP_001123483.1|refseq:NP_113639.4 go:"GO:0006629"(lipid metabolic process)|go:"GO:0006956"(complement activation)|go:"GO:0006958"(complement activation, classical pathway)|go:"GO:0009615"(response to virus)|go:"GO:0009986"(cell surface)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0017038"(protein import)|go:"GO:0031093"(platelet alpha granule lumen)|go:"GO:0031333"(negative regulation of protein-containing complex assembly)|go:"GO:0031334"(positive regulation of protein-containing complex assembly)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032286"(central nervous system myelin maintenance)|go:"GO:0032436"(positive regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0032760"(positive regulation of tumor necrosis factor production)|go:"GO:0032991"(protein-containing complex)|go:"GO:0005829"(cytosol)|ensembl:ENSG00000120885(gene)|ensembl:ENST00000316403(transcript)|ensembl:ENST00000405140(transcript)|ensembl:ENST00000523500(transcript)|go:"GO:0000902"(cell morphogenesis)|go:"GO:0001540"(amyloid-beta binding)|go:"GO:0001774"(microglial cell activation)|go:"GO:0001836"(release of cytochrome c from mitochondria)|go:"GO:0002434"(immune complex clearance)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0034366"(spherical high-density lipoprotein particle)|go:"GO:0042127"(regulation of cell population proliferation)|go:"GO:0042583"(chromaffin granule)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0043691"(reverse cholesterol transport)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045087"(innate immune response)|go:"GO:0045202"(synapse)|go:"GO:0045429"(positive regulation of nitric oxide biosynthetic process)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0048156"(tau protein binding)|go:"GO:0048260"(positive regulation of receptor-mediated endocytosis)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0050750"(low-density lipoprotein particle receptor binding)|go:"GO:0050821"(protein stabilization)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0051087"(chaperone binding)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|go:"GO:0051131"(chaperone-mediated protein complex assembly)|go:"GO:0051787"(misfolded protein binding)|go:"GO:0051788"(response to misfolded protein)|go:"GO:0061077"(chaperone-mediated protein folding)|go:"GO:0061518"(microglial cell proliferation)|go:"GO:0061740"(protein targeting to lysosome involved in chaperone-mediated autophagy)|go:"GO:0062023"(collagen-containing extracellular matrix)|go:"GO:0070062"(extracellular exosome)|go:"GO:0072562"(blood microparticle)|go:"GO:0090201"(negative regulation of release of cytochrome c from mitochondria)|go:"GO:0097193"(intrinsic apoptotic signaling pathway)|go:"GO:0097418"(neurofibrillary tangle)|go:"GO:0097440"(apical dendrite)|go:"GO:0099020"(perinuclear endoplasmic reticulum lumen)|go:"GO:0140597"(protein carrier chaperone)|go:"GO:1900221"(regulation of amyloid-beta clearance)|go:"GO:1901214"(regulation of neuron death)|go:"GO:1901216"(positive regulation of neuron death)|go:"GO:1902004"(positive regulation of amyloid-beta formation)|go:"GO:1902230"(negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage)|go:"GO:1902430"(negative regulation of amyloid-beta formation)|go:"GO:1902847"(regulation of neuronal signal transduction)|go:"GO:1902949"(positive regulation of tau-protein kinase activity)|go:"GO:1902998"(positive regulation of neurofibrillary tangle assembly)|go:"GO:1903573"(negative regulation of response to endoplasmic reticulum stress)|go:"GO:1905892"(negative regulation of cellular response to thapsigargin)|go:"GO:1905895"(negative regulation of cellular response to tunicamycin)|go:"GO:1905907"(negative regulation of amyloid fibril formation)|go:"GO:1905908"(positive regulation of amyloid fibril formation)|go:"GO:2000060"(positive regulation of ubiquitin-dependent protein catabolic process)|go:"GO:2001244"(positive regulation of intrinsic apoptotic signaling pathway)|interpro:IPR000753(Clusterin-like)|interpro:IPR016014(Clusterin, N-terminal)|interpro:IPR016015(Clusterin, C-terminal)|interpro:IPR016016(Clusterin)|interpro:IPR033986|mint:P10909|reactome:R-HSA-114608|reactome:R-HSA-166665|reactome:R-HSA-6803157|go:"GO:0060548"(negative regulation of cell death)|reactome:R-HSA-977606|refseq:NP_001822.3|dip:DIP-37546N - - - comment:"Proteins significantly enriched by immunoprecipitation with 34ED556 (T1) anti-TEX101 antibody in human sperm cells from pre-vasectomy semen samples."|figure legend:Fig. 2B, supplemental Table S6|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-spermatozoa)|taxid:9606(Homo sapiens) - 2020/03/24 2020/04/07 rogid:ZE4tXTFi7lUCcIbCL4KHzY3a6xM9606 rogid:qlCJp4zYTklC3YZNQvbLmZBiz4U9606 rigid:TX1oljMyfkimcULEvhCJR/BRAW4 false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9BY14 uniprotkb:P11021 intact:EBI-12549378|ensembl:ENSP00000472769|uniprotkb:Q7L5R2|uniprotkb:Q9BPY7 intact:EBI-354921|ensembl:ENSP00000324173|uniprotkb:Q2EF78|uniprotkb:Q9NPF1|uniprotkb:Q9UK02|uniprotkb:B0QZ61 psi-mi:tx101_human(display_long)|uniprotkb:TEX101(gene name)|psi-mi:TEX101(display_short)|uniprotkb:Cell surface receptor NYD-SP8(gene name synonym)|uniprotkb:SGRG(gene name synonym)|uniprotkb:Scleroderma-associated autoantigen(gene name synonym)|uniprotkb:Spermatogenesis-related gene protein(gene name synonym)|uniprotkb:UNQ867/PRO1884(orf name) psi-mi:bip_human(display_long)|uniprotkb:HSPA5(gene name)|psi-mi:HSPA5(display_short)|uniprotkb:GRP78(gene name synonym)|uniprotkb:Immunoglobulin heavy chain-binding protein(gene name synonym)|uniprotkb:78 kDa glucose-regulated protein(gene name synonym)|uniprotkb:Binding-immunoglobulin protein(gene name synonym)|uniprotkb:Heat shock protein 70 family protein 5(gene name synonym)|uniprotkb:Heat shock protein family A member 5(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Schiza et al. (2018) imex:IM-28077|pubmed:30097533 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-25505396|imex:IM-28077-7 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000131126(gene)|ensembl:ENST00000598265(transcript)|go:"GO:0001669"(acrosomal vesicle)|go:"GO:0002080"(acrosomal membrane)|go:"GO:0005576"(extracellular region)|go:"GO:0005886"(plasma membrane)|go:"GO:0007339"(binding of sperm to zona pellucida)|go:"GO:0009566"(fertilization)|go:"GO:0030317"(flagellated sperm motility)|go:"GO:0044853"(plasma membrane raft)|go:"GO:0046658"(anchored component of plasma membrane)|go:"GO:1901317"(regulation of flagellated sperm motility)|interpro:IPR016054(Ly-6 antigen / uPA receptor -like)|rcsb pdb:7BPR|reactome:R-HSA-163125|refseq:NP_001123483.1|refseq:NP_113639.4 ensembl:ENSG00000044574(gene)|ensembl:ENST00000324460(transcript)|go:"GO:0001554"(luteolysis)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005788"(endoplasmic reticulum lumen)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005790"(smooth endoplasmic reticulum)|go:"GO:0005793"(endoplasmic reticulum-Golgi intermediate compartment)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005925"(focal adhesion)|go:"GO:0006983"(ER overload response)|refseq:NP_005338.1|go:"GO:0009986"(cell surface)|go:"GO:0010976"(positive regulation of neuron projection development)|go:"GO:0016020"(membrane)|go:"GO:0016887"(ATP hydrolysis activity)|go:"GO:0019899"(enzyme binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0021589"(cerebellum structural organization)|go:"GO:0021680"(cerebellar Purkinje cell layer development)|go:"GO:0021762"(substantia nigra development)|go:"GO:0030176"(integral component of endoplasmic reticulum membrane)|go:"GO:0030182"(neuron differentiation)|go:"GO:0030433"(ubiquitin-dependent ERAD pathway)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0030496"(midbody)|go:"GO:0030512"(negative regulation of transforming growth factor beta receptor signaling pathway)|go:"GO:0030968"(endoplasmic reticulum unfolded protein response)|go:"GO:0031072"(heat shock protein binding)|go:"GO:0031204"(posttranslational protein targeting to membrane, translocation)|go:"GO:0031333"(negative regulation of protein-containing complex assembly)|go:"GO:0031398"(positive regulation of protein ubiquitination)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034620"(cellular response to unfolded protein)|go:"GO:0034663"(endoplasmic reticulum chaperone complex)|go:"GO:0034975"(protein folding in endoplasmic reticulum)|go:"GO:0035437"(maintenance of protein localization in endoplasmic reticulum)|go:"GO:0035690"|go:"GO:0042026"(protein refolding)|go:"GO:0042149"(cellular response to glucose starvation)|go:"GO:0042220"(response to cocaine)|go:"GO:0042470"(melanosome)|go:"GO:0043022"(ribosome binding)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0044183"(protein folding chaperone)|go:"GO:0045296"(cadherin binding)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0051085"(chaperone cofactor-dependent protein refolding)|go:"GO:0051087"(chaperone binding)|go:"GO:0051402"(neuron apoptotic process)|go:"GO:0051787"(misfolded protein binding)|go:"GO:0060904"(regulation of protein folding in endoplasmic reticulum)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071236"(cellular response to antibiotic)|go:"GO:0071277"(cellular response to calcium ion)|go:"GO:0071287"(cellular response to manganese ion)|go:"GO:0071320"(cellular response to cAMP)|go:"GO:0071353"(cellular response to interleukin-4)|go:"GO:0071480"(cellular response to gamma radiation)|go:"GO:0097501"(stress response to metal ion)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|go:"GO:1901998"(toxin transport)|go:"GO:1903891"(regulation of ATF6-mediated unfolded protein response)|go:"GO:1903894"(regulation of IRE1-mediated unfolded protein response)|go:"GO:1903895"(negative regulation of IRE1-mediated unfolded protein response)|go:"GO:1903897"(regulation of PERK-mediated unfolded protein response)|go:"GO:1904313"(response to methamphetamine hydrochloride)|go:"GO:1990090"(cellular response to nerve growth factor stimulus)|go:"GO:1990440"(positive regulation of transcription from RNA polymerase II promoter in response to endoplasmic reticulum stress)|interpro:IPR013126(Heat shock protein 70)|interpro:IPR018181|interpro:IPR029047|interpro:IPR029048|interpro:IPR042050|interpro:IPR043129|mint:P11021|rcsb pdb:3IUC|rcsb pdb:3LDL|rcsb pdb:3LDN|rcsb pdb:3LDO|rcsb pdb:3LDP|rcsb pdb:5E84|rcsb pdb:5E85|rcsb pdb:5E86|rcsb pdb:5EVZ|rcsb pdb:5EX5|rcsb pdb:5EXW|rcsb pdb:5EY4|rcsb pdb:5F0X|rcsb pdb:5F1X|rcsb pdb:5F2R|rcsb pdb:6ASY|rcsb pdb:6CZ1|rcsb pdb:6DFM|rcsb pdb:6DFO|rcsb pdb:6DO2|rcsb pdb:6DWS|rcsb pdb:6ZMD|reactome:R-HSA-114608|reactome:R-HSA-3371453|reactome:R-HSA-381033|reactome:R-HSA-381042|reactome:R-HSA-381070|reactome:R-HSA-381183|reactome:R-HSA-983170|dip:DIP-33189N - - - comment:"Proteins significantly enriched by immunoprecipitation with 34ED556 (T1) anti-TEX101 antibody in human sperm cells from pre-vasectomy semen samples."|figure legend:Fig. 2B, supplemental Table S6|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-spermatozoa)|taxid:9606(Homo sapiens) - 2020/03/24 2020/04/07 rogid:ZE4tXTFi7lUCcIbCL4KHzY3a6xM9606 rogid:O8nTjCciNhD3QsbZmbolQ1IIMn49606 rigid:TX1oljMyfkimcULEvhCJR/BRAW4 false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9BY14 uniprotkb:Q96HR9 intact:EBI-12549378|ensembl:ENSP00000472769|uniprotkb:Q7L5R2|uniprotkb:Q9BPY7 intact:EBI-750345|uniprotkb:Q96LM0|uniprotkb:B2RE01|uniprotkb:A0A1L5BXV3|uniprotkb:D6W5Z0|ensembl:ENSP00000378861 psi-mi:tx101_human(display_long)|uniprotkb:TEX101(gene name)|psi-mi:TEX101(display_short)|uniprotkb:Cell surface receptor NYD-SP8(gene name synonym)|uniprotkb:SGRG(gene name synonym)|uniprotkb:Scleroderma-associated autoantigen(gene name synonym)|uniprotkb:Spermatogenesis-related gene protein(gene name synonym)|uniprotkb:UNQ867/PRO1884(orf name) psi-mi:reep6_human(display_long)|uniprotkb:Polyposis locus protein 1-like 1(gene name synonym)|uniprotkb:REEP6(gene name)|psi-mi:REEP6(display_short)|uniprotkb:C19orf32(gene name synonym)|uniprotkb:DP1L1(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Schiza et al. (2018) imex:IM-28077|pubmed:30097533 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-25505396|imex:IM-28077-7 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000131126(gene)|ensembl:ENST00000598265(transcript)|go:"GO:0001669"(acrosomal vesicle)|go:"GO:0002080"(acrosomal membrane)|go:"GO:0005576"(extracellular region)|go:"GO:0005886"(plasma membrane)|go:"GO:0007339"(binding of sperm to zona pellucida)|go:"GO:0009566"(fertilization)|go:"GO:0030317"(flagellated sperm motility)|go:"GO:0044853"(plasma membrane raft)|go:"GO:0046658"(anchored component of plasma membrane)|go:"GO:1901317"(regulation of flagellated sperm motility)|interpro:IPR016054(Ly-6 antigen / uPA receptor -like)|rcsb pdb:7BPR|reactome:R-HSA-163125|refseq:NP_001123483.1|refseq:NP_113639.4 refseq:NP_612402.1|refseq:NP_001316485.1|ensembl:ENSG00000115255(gene)|ensembl:ENST00000395479(transcript)|go:"GO:0001917"(photoreceptor inner segment)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0007029"(endoplasmic reticulum organization)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030665"(clathrin-coated vesicle membrane)|go:"GO:0032386"(regulation of intracellular transport)|go:"GO:0050908"(detection of light stimulus involved in visual perception)|interpro:IPR004345(TB2/DP1 and HVA22 related protein)|mint:Q96HR9|reactome:R-HSA-381753|go:"GO:0005634"(nucleus) - - - comment:"Proteins significantly enriched by immunoprecipitation with 34ED556 (T1) anti-TEX101 antibody in human sperm cells from pre-vasectomy semen samples."|figure legend:Fig. 2B, supplemental Table S6|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-spermatozoa)|taxid:9606(Homo sapiens) - 2020/03/24 2020/04/07 rogid:ZE4tXTFi7lUCcIbCL4KHzY3a6xM9606 rogid:pB8AjjNTpmaaLJ8j7MCBM45UAHE9606 rigid:TX1oljMyfkimcULEvhCJR/BRAW4 false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9BY14 uniprotkb:P23786 intact:EBI-12549378|ensembl:ENSP00000472769|uniprotkb:Q7L5R2|uniprotkb:Q9BPY7 intact:EBI-6269566|ensembl:ENSP00000360541|uniprotkb:B2R6S0|uniprotkb:Q5SW68|uniprotkb:Q9BQ26 psi-mi:tx101_human(display_long)|uniprotkb:TEX101(gene name)|psi-mi:TEX101(display_short)|uniprotkb:Cell surface receptor NYD-SP8(gene name synonym)|uniprotkb:SGRG(gene name synonym)|uniprotkb:Scleroderma-associated autoantigen(gene name synonym)|uniprotkb:Spermatogenesis-related gene protein(gene name synonym)|uniprotkb:UNQ867/PRO1884(orf name) psi-mi:cpt2_human(display_long)|uniprotkb:CPT2(gene name)|psi-mi:CPT2(display_short)|uniprotkb:CPT1(gene name synonym)|uniprotkb:Carnitine palmitoyltransferase II(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Schiza et al. (2018) imex:IM-28077|pubmed:30097533 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-25505396|imex:IM-28077-7 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000131126(gene)|ensembl:ENST00000598265(transcript)|go:"GO:0001669"(acrosomal vesicle)|go:"GO:0002080"(acrosomal membrane)|go:"GO:0005576"(extracellular region)|go:"GO:0005886"(plasma membrane)|go:"GO:0007339"(binding of sperm to zona pellucida)|go:"GO:0009566"(fertilization)|go:"GO:0030317"(flagellated sperm motility)|go:"GO:0044853"(plasma membrane raft)|go:"GO:0046658"(anchored component of plasma membrane)|go:"GO:1901317"(regulation of flagellated sperm motility)|interpro:IPR016054(Ly-6 antigen / uPA receptor -like)|rcsb pdb:7BPR|reactome:R-HSA-163125|refseq:NP_001123483.1|refseq:NP_113639.4 ensembl:ENSG00000157184(gene)|ensembl:ENST00000371486(transcript)|go:"GO:0001676"(long-chain fatty acid metabolic process)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0006635"(fatty acid beta-oxidation)|go:"GO:0006853"(carnitine shuttle)|go:"GO:0008458"(carnitine O-octanoyltransferase activity)|go:"GO:0009437"(carnitine metabolic process)|go:"GO:0016746"(acyltransferase activity)|go:"GO:0120162"(positive regulation of cold-induced thermogenesis)|interpro:IPR000542(Acyltransferase ChoActase/COT/CPT)|interpro:IPR023213|interpro:IPR039551|interpro:IPR042572|reactome:R-HSA-1989781|reactome:R-HSA-200425|go:"GO:0004095"(carnitine O-palmitoyltransferase activity)|refseq:NP_000089.1 - - - comment:"Proteins significantly enriched by immunoprecipitation with 34ED556 (T1) anti-TEX101 antibody in human sperm cells from pre-vasectomy semen samples."|figure legend:Fig. 2B, supplemental Table S6|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-spermatozoa)|taxid:9606(Homo sapiens) - 2020/03/24 2020/04/07 rogid:ZE4tXTFi7lUCcIbCL4KHzY3a6xM9606 rogid:maFH51Fz1PYXUzBwLPr3sGlVkcY9606 rigid:TX1oljMyfkimcULEvhCJR/BRAW4 false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9BY14 uniprotkb:Q99832 intact:EBI-12549378|ensembl:ENSP00000472769|uniprotkb:Q7L5R2|uniprotkb:Q9BPY7 intact:EBI-357046|uniprotkb:B7WNW9|uniprotkb:O14871|uniprotkb:Q6FI26|uniprotkb:A8K7E6|uniprotkb:A8MWI8|uniprotkb:B7Z4T9|uniprotkb:B7Z4Z7|ensembl:ENSP00000258091 psi-mi:tx101_human(display_long)|uniprotkb:TEX101(gene name)|psi-mi:TEX101(display_short)|uniprotkb:Cell surface receptor NYD-SP8(gene name synonym)|uniprotkb:SGRG(gene name synonym)|uniprotkb:Scleroderma-associated autoantigen(gene name synonym)|uniprotkb:Spermatogenesis-related gene protein(gene name synonym)|uniprotkb:UNQ867/PRO1884(orf name) psi-mi:tcph_human(display_long)|uniprotkb:CCT7(gene name)|psi-mi:CCT7(display_short)|uniprotkb:CCTH(gene name synonym)|uniprotkb:NIP7-1(gene name synonym)|uniprotkb:CCT-eta(gene name synonym)|uniprotkb:HIV-1 Nef-interacting protein(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Schiza et al. (2018) imex:IM-28077|pubmed:30097533 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-25505396|imex:IM-28077-7 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000131126(gene)|ensembl:ENST00000598265(transcript)|go:"GO:0001669"(acrosomal vesicle)|go:"GO:0002080"(acrosomal membrane)|go:"GO:0005576"(extracellular region)|go:"GO:0005886"(plasma membrane)|go:"GO:0007339"(binding of sperm to zona pellucida)|go:"GO:0009566"(fertilization)|go:"GO:0030317"(flagellated sperm motility)|go:"GO:0044853"(plasma membrane raft)|go:"GO:0046658"(anchored component of plasma membrane)|go:"GO:1901317"(regulation of flagellated sperm motility)|interpro:IPR016054(Ly-6 antigen / uPA receptor -like)|rcsb pdb:7BPR|reactome:R-HSA-163125|refseq:NP_001123483.1|refseq:NP_113639.4 dip:DIP-51608N|refseq:NP_006420.1|refseq:XP_011530780.1|refseq:XP_011530781.1|refseq:NP_001009570.1|refseq:NP_001159756.1|refseq:NP_001159757.1|ensembl:ENSG00000135624(gene)|ensembl:ENST00000258091(transcript)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005832"(chaperonin-containing T-complex)|go:"GO:0005874"(microtubule)|go:"GO:0006457"(protein folding)|go:"GO:0007339"(binding of sperm to zona pellucida)|go:"GO:0032212"(positive regulation of telomere maintenance via telomerase)|go:"GO:0044183"(protein folding chaperone)|go:"GO:0044297"(cell body)|go:"GO:0050821"(protein stabilization)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0070062"(extracellular exosome)|go:"GO:1901998"(toxin transport)|go:"GO:1904851"(positive regulation of establishment of protein localization to telomere)|go:"GO:1904871"(positive regulation of protein localization to Cajal body)|go:"GO:1904874"(positive regulation of telomerase RNA localization to Cajal body)|interpro:IPR002194(Chaperonin TCP-1, conserved site)|interpro:IPR002423(Chaperonin Cpn60/TCP-1)|interpro:IPR012720(T-complex protein 1, eta subunit)|interpro:IPR017998|interpro:IPR027409|interpro:IPR027410|interpro:IPR027413|mint:Q99832|rcsb pdb:6NR8|rcsb pdb:6NR9|rcsb pdb:6NRA|rcsb pdb:6NRB|rcsb pdb:6NRC|rcsb pdb:6NRD|rcsb pdb:6QB8|rcsb pdb:7LUM|rcsb pdb:7LUP|reactome:R-HSA-389957|reactome:R-HSA-389960|reactome:R-HSA-390450|reactome:R-HSA-390471|reactome:R-HSA-6814122|reactome:R-HSA-9013418|reactome:R-HSA-9013422 - - - comment:"Proteins significantly enriched by immunoprecipitation with 34ED556 (T1) anti-TEX101 antibody in human sperm cells from pre-vasectomy semen samples."|figure legend:Fig. 2B, supplemental Table S6|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-spermatozoa)|taxid:9606(Homo sapiens) - 2020/03/24 2020/04/07 rogid:ZE4tXTFi7lUCcIbCL4KHzY3a6xM9606 rogid:buiW7iGdAbfcld/zMJOrkR2jxRo9606 rigid:TX1oljMyfkimcULEvhCJR/BRAW4 false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9BY14 uniprotkb:P08473 intact:EBI-12549378|ensembl:ENSP00000472769|uniprotkb:Q7L5R2|uniprotkb:Q9BPY7 intact:EBI-353759|uniprotkb:Q3MIX4|uniprotkb:A8K6U6|uniprotkb:D3DNJ9|ensembl:ENSP00000353679|ensembl:ENSP00000417079|ensembl:ENSP00000418525|ensembl:ENSP00000418791|ensembl:ENSP00000419653|ensembl:ENSP00000420389|ensembl:ENSP00000420542|ensembl:ENSP00000502021|ensembl:ENSP00000505211|ensembl:ENSP00000505690 psi-mi:tx101_human(display_long)|uniprotkb:TEX101(gene name)|psi-mi:TEX101(display_short)|uniprotkb:Cell surface receptor NYD-SP8(gene name synonym)|uniprotkb:SGRG(gene name synonym)|uniprotkb:Scleroderma-associated autoantigen(gene name synonym)|uniprotkb:Spermatogenesis-related gene protein(gene name synonym)|uniprotkb:UNQ867/PRO1884(orf name) psi-mi:nep_human(display_long)|uniprotkb:MME(gene name)|psi-mi:MME(display_short)|uniprotkb:EPN(gene name synonym)|uniprotkb:Neutral endopeptidase 24.11(gene name synonym)|uniprotkb:Enkephalinase(gene name synonym)|uniprotkb:Atriopeptidase(gene name synonym)|uniprotkb:Common acute lymphocytic leukemia antigen(gene name synonym)|uniprotkb:Skin fibroblast elastase(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Schiza et al. (2018) imex:IM-28077|pubmed:30097533 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-25505396|imex:IM-28077-7 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000131126(gene)|ensembl:ENST00000598265(transcript)|go:"GO:0001669"(acrosomal vesicle)|go:"GO:0002080"(acrosomal membrane)|go:"GO:0005576"(extracellular region)|go:"GO:0005886"(plasma membrane)|go:"GO:0007339"(binding of sperm to zona pellucida)|go:"GO:0009566"(fertilization)|go:"GO:0030317"(flagellated sperm motility)|go:"GO:0044853"(plasma membrane raft)|go:"GO:0046658"(anchored component of plasma membrane)|go:"GO:1901317"(regulation of flagellated sperm motility)|interpro:IPR016054(Ly-6 antigen / uPA receptor -like)|rcsb pdb:7BPR|reactome:R-HSA-163125|refseq:NP_001123483.1|refseq:NP_113639.4 refseq:NP_000893.2|refseq:NP_009218.2|refseq:NP_009219.2|refseq:NP_009220.2|refseq:XP_011511157.1|refseq:XP_011511158.1|refseq:XP_011511159.1|ensembl:ENSG00000196549(gene)|ensembl:ENST00000360490(transcript)|ensembl:ENST00000460393(transcript)|ensembl:ENST00000462745(transcript)|ensembl:ENST00000473730(transcript)|ensembl:ENST00000491026(transcript)|ensembl:ENST00000492661(transcript)|ensembl:ENST00000493237(transcript)|ensembl:ENST00000675418(transcript)|ensembl:ENST00000680057(transcript)|ensembl:ENST00000680282(transcript)|go:"GO:0001786"(phosphatidylserine binding)|go:"GO:0001822"(kidney development)|go:"GO:0001890"(placenta development)|go:"GO:0002003"(angiotensin maturation)|go:"GO:0004175"(endopeptidase activity)|go:"GO:0004222"(metalloendopeptidase activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005769"(early endosome)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0005903"(brush border)|go:"GO:0005925"(focal adhesion)|go:"GO:0006508"(proteolysis)|go:"GO:0006518"(peptide metabolic process)|go:"GO:0007568"(aging)|go:"GO:0007611"(learning or memory)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0008237"(metallopeptidase activity)|go:"GO:0008238"(exopeptidase activity)|go:"GO:0008270"(zinc ion binding)|go:"GO:0009986"(cell surface)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016485"(protein processing)|go:"GO:0019233"(sensory perception of pain)|go:"GO:0030324"(lung development)|go:"GO:0030424"(axon)|go:"GO:0030425"(dendrite)|go:"GO:0030667"(secretory granule membrane)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0042277"(peptide binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043025"(neuronal cell body)|go:"GO:0044306"(neuron projection terminus)|go:"GO:0045121"(membrane raft)|go:"GO:0045202"(synapse)|go:"GO:0046449"(creatinine metabolic process)|go:"GO:0050435"(amyloid-beta metabolic process)|go:"GO:0050769"(positive regulation of neurogenesis)|go:"GO:0061837"(neuropeptide processing)|go:"GO:0070012"(oligopeptidase activity)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071345"(cellular response to cytokine stimulus)|go:"GO:0071492"(cellular response to UV-A)|go:"GO:0071493"(cellular response to UV-B)|go:"GO:0090399"(replicative senescence)|go:"GO:0097242"(amyloid-beta clearance)|go:"GO:0098793"(presynapse)|go:"GO:0150094"(amyloid-beta clearance by cellular catabolic process)|go:"GO:1900273"(positive regulation of long-term synaptic potentiation)|go:"GO:1901612"(cardiolipin binding)|interpro:IPR000718(Peptidase M13, neprilysin)|interpro:IPR008753(Peptidase M13)|interpro:IPR018497|interpro:IPR024079|interpro:IPR029727|interpro:IPR042089|rcsb pdb:1DL9|rcsb pdb:1DMT|rcsb pdb:1QVD|rcsb pdb:1R1H|rcsb pdb:1R1I|rcsb pdb:1R1J|rcsb pdb:1Y8J|rcsb pdb:2QPJ|rcsb pdb:2YB9|rcsb pdb:4CTH|rcsb pdb:5JMY|rcsb pdb:6GID|rcsb pdb:6SH1|rcsb pdb:6SH2|rcsb pdb:6SUK|rcsb pdb:6SVY|rcsb pdb:6THP|rcsb pdb:6XVP|reactome:R-HSA-2022377|reactome:R-HSA-6798695|refseq:XP_006713709.1|refseq:XP_006713710.1 - - - comment:"Proteins significantly enriched by immunoprecipitation with 34ED556 (T1) anti-TEX101 antibody in human sperm cells from pre-vasectomy semen samples."|figure legend:Fig. 2B, supplemental Table S6|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-spermatozoa)|taxid:9606(Homo sapiens) - 2020/03/24 2020/04/07 rogid:ZE4tXTFi7lUCcIbCL4KHzY3a6xM9606 rogid:kc8XvGW1B4gXM3+1br/Ivp9+cPE9606 rigid:TX1oljMyfkimcULEvhCJR/BRAW4 false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9BY14 uniprotkb:Q00610 intact:EBI-12549378|ensembl:ENSP00000472769|uniprotkb:Q7L5R2|uniprotkb:Q9BPY7 intact:EBI-354967|intact:EBI-28974011|ensembl:ENSP00000269122|uniprotkb:Q6N0A0|uniprotkb:Q86TF2|uniprotkb:D3DU00 psi-mi:tx101_human(display_long)|uniprotkb:TEX101(gene name)|psi-mi:TEX101(display_short)|uniprotkb:Cell surface receptor NYD-SP8(gene name synonym)|uniprotkb:SGRG(gene name synonym)|uniprotkb:Scleroderma-associated autoantigen(gene name synonym)|uniprotkb:Spermatogenesis-related gene protein(gene name synonym)|uniprotkb:UNQ867/PRO1884(orf name) psi-mi:clh1_human(display_long)|uniprotkb:Clathrin heavy chain on chromosome 17(gene name synonym)|uniprotkb:CLTC(gene name)|psi-mi:CLTC(display_short)|uniprotkb:CLH17(gene name synonym)|uniprotkb:KIAA0034(gene name synonym)|uniprotkb:CLTCL2(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Schiza et al. (2018) imex:IM-28077|pubmed:30097533 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-25505396|imex:IM-28077-7 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000131126(gene)|ensembl:ENST00000598265(transcript)|go:"GO:0001669"(acrosomal vesicle)|go:"GO:0002080"(acrosomal membrane)|go:"GO:0005576"(extracellular region)|go:"GO:0005886"(plasma membrane)|go:"GO:0007339"(binding of sperm to zona pellucida)|go:"GO:0009566"(fertilization)|go:"GO:0030317"(flagellated sperm motility)|go:"GO:0044853"(plasma membrane raft)|go:"GO:0046658"(anchored component of plasma membrane)|go:"GO:1901317"(regulation of flagellated sperm motility)|interpro:IPR016054(Ly-6 antigen / uPA receptor -like)|rcsb pdb:7BPR|reactome:R-HSA-163125|refseq:NP_001123483.1|refseq:NP_113639.4 ensembl:ENSG00000141367(gene)|ensembl:ENST00000269122(transcript)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0001649"(osteoblast differentiation)|go:"GO:0003723"(RNA binding)|go:"GO:0003725"(double-stranded RNA binding)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005764"(lysosome)|go:"GO:0005768"(endosome)|go:"GO:0005819"(spindle)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005925"(focal adhesion)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006898"(receptor-mediated endocytosis)|go:"GO:0006914"(autophagy)|go:"GO:0016020"(membrane)|go:"GO:0019901"(protein kinase binding)|go:"GO:0050750"(low-density lipoprotein particle receptor binding)|go:"GO:0030118"(clathrin coat)|go:"GO:0030130"(clathrin coat of trans-Golgi network vesicle)|go:"GO:0051301"(cell division)|go:"GO:0060236"(regulation of mitotic spindle organization)|go:"GO:0030132"(clathrin coat of coated pit)|go:"GO:0030136"(clathrin-coated vesicle)|go:"GO:0030669"(clathrin-coated endocytic vesicle membrane)|go:"GO:0070062"(extracellular exosome)|go:"GO:0031623"(receptor internalization)|go:"GO:0032051"(clathrin light chain binding)|go:"GO:0032588"(trans-Golgi network membrane)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033572"(transferrin transport)|go:"GO:0036020"(endolysosome membrane)|go:"GO:0042147"(retrograde transport, endosome to Golgi)|go:"GO:0042470"(melanosome)|go:"GO:0045334"(clathrin-coated endocytic vesicle)|go:"GO:0048268"(clathrin coat assembly)|refseq:NP_004850.1|ensembl:ENSP00000269122|ensembl:ENST00000393043|ensembl:ENSP00000376763|go:"GO:0071439"(clathrin complex)|go:"GO:0072583"(clathrin-dependent endocytosis)|go:"GO:0072686"(mitotic spindle)|go:"GO:0097718"(disordered domain specific binding)|go:"GO:0150093"(amyloid-beta clearance by transcytosis)|go:"GO:1900126"(negative regulation of hyaluronan biosynthetic process)|go:"GO:1903077"(negative regulation of protein localization to plasma membrane)|go:"GO:1903561"(extracellular vesicle)|go:"GO:1990381"(ubiquitin-specific protease binding)|go:"GO:1990498"(mitotic spindle microtubule)|interpro:IPR000547(Clathrin, heavy chain/VPS, 7-fold repeat)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR015348(Clathrin, heavy chain, linker, core motif)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR016025(Clathrin, heavy chain, linker and propeller)|interpro:IPR016341(Clathrin, heavy chain)|interpro:IPR022365|mint:Q00610|rcsb pdb:2XZG|rcsb pdb:4G55|rcsb pdb:6E4L|rcsb pdb:6QNN|rcsb pdb:6QNP|reactome:R-HSA-168275|reactome:R-HSA-177504|reactome:R-HSA-190873|reactome:R-HSA-196025|reactome:R-HSA-2132295|reactome:R-HSA-3928665|reactome:R-HSA-432720|reactome:R-HSA-432722|reactome:R-HSA-437239|reactome:R-HSA-5099900|reactome:R-HSA-5140745|reactome:R-HSA-8856825|reactome:R-HSA-8856828|reactome:R-HSA-8866427|reactome:R-HSA-8964038|reactome:R-HSA-9013420|reactome:R-HSA-9013424 - - - comment:"Proteins significantly enriched by immunoprecipitation with 34ED556 (T1) anti-TEX101 antibody in human sperm cells from pre-vasectomy semen samples."|figure legend:Fig. 2B, supplemental Table S6|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-spermatozoa)|taxid:9606(Homo sapiens) - 2020/03/24 2020/04/07 rogid:ZE4tXTFi7lUCcIbCL4KHzY3a6xM9606 rogid:oGsLXL5J5MHO+ronpDIG9hJ11sU9606 rigid:TX1oljMyfkimcULEvhCJR/BRAW4 false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9BY14 uniprotkb:O43760 intact:EBI-12549378|ensembl:ENSP00000472769|uniprotkb:Q7L5R2|uniprotkb:Q9BPY7 intact:EBI-2826419|intact:EBI-4289558|uniprotkb:O43762|uniprotkb:Q3KQZ2|uniprotkb:Q658S7|ensembl:ENSP00000225777|ensembl:ENSP00000465678 psi-mi:tx101_human(display_long)|uniprotkb:TEX101(gene name)|psi-mi:TEX101(display_short)|uniprotkb:Cell surface receptor NYD-SP8(gene name synonym)|uniprotkb:SGRG(gene name synonym)|uniprotkb:Scleroderma-associated autoantigen(gene name synonym)|uniprotkb:Spermatogenesis-related gene protein(gene name synonym)|uniprotkb:UNQ867/PRO1884(orf name) psi-mi:sng2_human(display_long)|uniprotkb:SYNGR2(gene name)|psi-mi:SYNGR2(display_short)|uniprotkb:Cellugyrin(gene name synonym)|uniprotkb:UNQ352/PRO615(orf name) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Schiza et al. (2018) imex:IM-28077|pubmed:30097533 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-25505396|imex:IM-28077-7 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000131126(gene)|ensembl:ENST00000598265(transcript)|go:"GO:0001669"(acrosomal vesicle)|go:"GO:0002080"(acrosomal membrane)|go:"GO:0005576"(extracellular region)|go:"GO:0005886"(plasma membrane)|go:"GO:0007339"(binding of sperm to zona pellucida)|go:"GO:0009566"(fertilization)|go:"GO:0030317"(flagellated sperm motility)|go:"GO:0044853"(plasma membrane raft)|go:"GO:0046658"(anchored component of plasma membrane)|go:"GO:1901317"(regulation of flagellated sperm motility)|interpro:IPR016054(Ly-6 antigen / uPA receptor -like)|rcsb pdb:7BPR|reactome:R-HSA-163125|refseq:NP_001123483.1|refseq:NP_113639.4 refseq:NP_004701.1|refseq:NP_001307452.1|ensembl:ENSG00000108639(gene)|ensembl:ENST00000225777(transcript)|ensembl:ENST00000585591(transcript)|go:"GO:0005811"(lipid droplet)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030672"(synaptic vesicle membrane)|go:"GO:0031594"(neuromuscular junction)|go:"GO:0045055"(regulated exocytosis)|go:"GO:0048499"(synaptic vesicle membrane organization)|go:"GO:0070062"(extracellular exosome)|interpro:IPR008253(Marvel)|interpro:IPR016579(Synaptogyrin)|mint:O43760|refseq:XP_005257849.1 - - - comment:"Proteins significantly enriched by immunoprecipitation with 34ED556 (T1) anti-TEX101 antibody in human sperm cells from pre-vasectomy semen samples."|figure legend:Fig. 2B, supplemental Table S6|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-spermatozoa)|taxid:9606(Homo sapiens) - 2020/03/24 2020/04/07 rogid:ZE4tXTFi7lUCcIbCL4KHzY3a6xM9606 rogid:RuUsRvpeTl8Akv3c3s7rt0zuoKU9606 rigid:TX1oljMyfkimcULEvhCJR/BRAW4 false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9BY14 uniprotkb:P19367 intact:EBI-12549378|ensembl:ENSP00000472769|uniprotkb:Q7L5R2|uniprotkb:Q9BPY7 intact:EBI-713162|uniprotkb:Q5VTC3|uniprotkb:Q96HC8|uniprotkb:Q9NNZ4|uniprotkb:O43443|uniprotkb:O43444|uniprotkb:O75574|uniprotkb:Q9NNZ5|uniprotkb:E9PCK0|ensembl:ENSP00000352398 psi-mi:tx101_human(display_long)|uniprotkb:TEX101(gene name)|psi-mi:TEX101(display_short)|uniprotkb:Cell surface receptor NYD-SP8(gene name synonym)|uniprotkb:SGRG(gene name synonym)|uniprotkb:Scleroderma-associated autoantigen(gene name synonym)|uniprotkb:Spermatogenesis-related gene protein(gene name synonym)|uniprotkb:UNQ867/PRO1884(orf name) psi-mi:hxk1_human(display_long)|uniprotkb:Hexokinase type I(gene name synonym)|uniprotkb:Brain form hexokinase(gene name synonym)|uniprotkb:HK1(gene name)|psi-mi:HK1(display_short)|uniprotkb:Hexokinase-A(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Schiza et al. (2018) imex:IM-28077|pubmed:30097533 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-25505396|imex:IM-28077-7 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000131126(gene)|ensembl:ENST00000598265(transcript)|go:"GO:0001669"(acrosomal vesicle)|go:"GO:0002080"(acrosomal membrane)|go:"GO:0005576"(extracellular region)|go:"GO:0005886"(plasma membrane)|go:"GO:0007339"(binding of sperm to zona pellucida)|go:"GO:0009566"(fertilization)|go:"GO:0030317"(flagellated sperm motility)|go:"GO:0044853"(plasma membrane raft)|go:"GO:0046658"(anchored component of plasma membrane)|go:"GO:1901317"(regulation of flagellated sperm motility)|interpro:IPR016054(Ly-6 antigen / uPA receptor -like)|rcsb pdb:7BPR|reactome:R-HSA-163125|refseq:NP_001123483.1|refseq:NP_113639.4 refseq:NP_000179.2|refseq:NP_277031.1|refseq:NP_277032.1|refseq:NP_277033.1|refseq:NP_277035.2|refseq:XP_011538034.1|refseq:NP_001309293.1|dip:DIP-56245N|go:"GO:0032731"(positive regulation of interleukin-1 beta production)|go:"GO:0042834"(peptidoglycan binding)|go:"GO:0045087"(innate immune response)|go:"GO:0045121"(membrane raft)|go:"GO:0046835"(carbohydrate phosphorylation)|go:"GO:0047931"(glucosamine kinase activity)|go:"GO:0051156"(glucose 6-phosphate metabolic process)|go:"GO:0061621"(canonical glycolysis)|go:"GO:0072655"(establishment of protein localization to mitochondrion)|go:"GO:0072656"(maintenance of protein location in mitochondrion)|interpro:IPR001312(Hexokinase)|interpro:IPR019807|interpro:IPR022672|interpro:IPR022673|interpro:IPR043129|mint:P19367|rcsb pdb:1CZA|rcsb pdb:1DGK|rcsb pdb:1HKB|rcsb pdb:1HKC|rcsb pdb:1QHA|rcsb pdb:4FOE|rcsb pdb:4FOI|rcsb pdb:4FPA|rcsb pdb:4FPB|reactome:R-HSA-5619056|reactome:R-HSA-70171|rcsb pdb:4F9O|ensembl:ENSG00000156515(gene)|ensembl:ENST00000359426(transcript)|go:"GO:0001678"(cellular glucose homeostasis)|go:"GO:0002720"(positive regulation of cytokine production involved in immune response)|go:"GO:0004340"(glucokinase activity)|go:"GO:0004396"(hexokinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005536"(glucose binding)|go:"GO:0005739"(mitochondrion)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005829"(cytosol)|go:"GO:0006002"(fructose 6-phosphate metabolic process)|go:"GO:0006013"(mannose metabolic process)|go:"GO:0006096"(glycolytic process)|go:"GO:0006954"(inflammatory response)|go:"GO:0008865"(fructokinase activity)|go:"GO:0019158"(mannokinase activity) - - - comment:"Proteins significantly enriched by immunoprecipitation with 34ED556 (T1) anti-TEX101 antibody in human sperm cells from pre-vasectomy semen samples."|figure legend:Fig. 2B, supplemental Table S6|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-spermatozoa)|taxid:9606(Homo sapiens) - 2020/03/24 2020/04/07 rogid:ZE4tXTFi7lUCcIbCL4KHzY3a6xM9606 rogid:cvNEGlnCikx3E17kNYTSI39EUfU9606 rigid:TX1oljMyfkimcULEvhCJR/BRAW4 false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9BY14 uniprotkb:P02656 intact:EBI-12549378|ensembl:ENSP00000472769|uniprotkb:Q7L5R2|uniprotkb:Q9BPY7 intact:EBI-1220113|uniprotkb:Q08E83|uniprotkb:Q6Q786|ensembl:ENSP00000227667 psi-mi:tx101_human(display_long)|uniprotkb:TEX101(gene name)|psi-mi:TEX101(display_short)|uniprotkb:Cell surface receptor NYD-SP8(gene name synonym)|uniprotkb:SGRG(gene name synonym)|uniprotkb:Scleroderma-associated autoantigen(gene name synonym)|uniprotkb:Spermatogenesis-related gene protein(gene name synonym)|uniprotkb:UNQ867/PRO1884(orf name) psi-mi:apoc3_human(display_long)|uniprotkb:APOC3(gene name)|psi-mi:APOC3(display_short)|uniprotkb:Apolipoprotein C3(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Schiza et al. (2018) imex:IM-28077|pubmed:30097533 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-25505396|imex:IM-28077-7 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000131126(gene)|ensembl:ENST00000598265(transcript)|go:"GO:0001669"(acrosomal vesicle)|go:"GO:0002080"(acrosomal membrane)|go:"GO:0005576"(extracellular region)|go:"GO:0005886"(plasma membrane)|go:"GO:0007339"(binding of sperm to zona pellucida)|go:"GO:0009566"(fertilization)|go:"GO:0030317"(flagellated sperm motility)|go:"GO:0044853"(plasma membrane raft)|go:"GO:0046658"(anchored component of plasma membrane)|go:"GO:1901317"(regulation of flagellated sperm motility)|interpro:IPR016054(Ly-6 antigen / uPA receptor -like)|rcsb pdb:7BPR|reactome:R-HSA-163125|refseq:NP_001123483.1|refseq:NP_113639.4 refseq:NP_000031.1|ensembl:ENSG00000110245(gene)|ensembl:ENST00000227667(transcript)|go:"GO:0005543"(phospholipid binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0005769"(early endosome)|go:"GO:0006641"(triglyceride metabolic process)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0010897"(negative regulation of triglyceride catabolic process)|go:"GO:0010903"(negative regulation of very-low-density lipoprotein particle remodeling)|go:"GO:0010916"(negative regulation of very-low-density lipoprotein particle clearance)|go:"GO:0010987"(negative regulation of high-density lipoprotein particle clearance)|go:"GO:0010989"(negative regulation of low-density lipoprotein particle clearance)|go:"GO:0015485"(cholesterol binding)|go:"GO:0019433"(triglyceride catabolic process)|go:"GO:0030234"(enzyme regulator activity)|go:"GO:0032489"(regulation of Cdc42 protein signal transduction)|go:"GO:0033344"(cholesterol efflux)|go:"GO:0033700"(phospholipid efflux)|go:"GO:0034361"(very-low-density lipoprotein particle)|go:"GO:0034363"(intermediate-density lipoprotein particle)|go:"GO:0034366"(spherical high-density lipoprotein particle)|go:"GO:0034375"(high-density lipoprotein particle remodeling)|go:"GO:0034379"(very-low-density lipoprotein particle assembly)|go:"GO:0034382"(chylomicron remnant clearance)|go:"GO:0042157"(lipoprotein metabolic process)|go:"GO:0042627"(chylomicron)|go:"GO:0042632"(cholesterol homeostasis)|go:"GO:0043691"(reverse cholesterol transport)|go:"GO:0045717"(negative regulation of fatty acid biosynthetic process)|go:"GO:0045833"(negative regulation of lipid metabolic process)|go:"GO:0048261"(negative regulation of receptor-mediated endocytosis)|go:"GO:0050995"(negative regulation of lipid catabolic process)|go:"GO:0051005"(negative regulation of lipoprotein lipase activity)|go:"GO:0055102"(lipase inhibitor activity)|go:"GO:0060621"(negative regulation of cholesterol import)|go:"GO:0062023"(collagen-containing extracellular matrix)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070328"(triglyceride homeostasis)|go:"GO:0070653"(high-density lipoprotein particle receptor binding)|interpro:IPR008403(Apolipoprotein CIII)|interpro:IPR038195|mint:P02656|rcsb pdb:2JQ3|reactome:R-HSA-8963888|reactome:R-HSA-8963901|reactome:R-HSA-8964058|reactome:R-HSA-975634 - - - comment:"Proteins significantly enriched by immunoprecipitation with 34ED556 (T1) anti-TEX101 antibody in human sperm cells from pre-vasectomy semen samples."|figure legend:Fig. 2B, supplemental Table S6|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-spermatozoa)|taxid:9606(Homo sapiens) - 2020/03/24 2020/04/07 rogid:ZE4tXTFi7lUCcIbCL4KHzY3a6xM9606 rogid:DDj33pQWDh0i5+mwMy16Dmg6JPg9606 rigid:TX1oljMyfkimcULEvhCJR/BRAW4 false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9BY14 uniprotkb:Q8TF72 intact:EBI-12549378|ensembl:ENSP00000472769|uniprotkb:Q7L5R2|uniprotkb:Q9BPY7 intact:EBI-2622657|uniprotkb:Q9P247|uniprotkb:Q5QTQ3|uniprotkb:Q96IR9|uniprotkb:Q6ZRW3|ensembl:ENSP00000296043 psi-mi:tx101_human(display_long)|uniprotkb:TEX101(gene name)|psi-mi:TEX101(display_short)|uniprotkb:Cell surface receptor NYD-SP8(gene name synonym)|uniprotkb:SGRG(gene name synonym)|uniprotkb:Scleroderma-associated autoantigen(gene name synonym)|uniprotkb:Spermatogenesis-related gene protein(gene name synonym)|uniprotkb:UNQ867/PRO1884(orf name) psi-mi:shrm3_human(display_long)|uniprotkb:KIAA1481(gene name synonym)|uniprotkb:SHRML(gene name synonym)|uniprotkb:Shroom-related protein(gene name synonym)|uniprotkb:MSTP013(orf name)|uniprotkb:SHROOM3(gene name)|psi-mi:SHROOM3(display_short) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Schiza et al. (2018) imex:IM-28077|pubmed:30097533 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-25505396|imex:IM-28077-7 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000131126(gene)|ensembl:ENST00000598265(transcript)|go:"GO:0001669"(acrosomal vesicle)|go:"GO:0002080"(acrosomal membrane)|go:"GO:0005576"(extracellular region)|go:"GO:0005886"(plasma membrane)|go:"GO:0007339"(binding of sperm to zona pellucida)|go:"GO:0009566"(fertilization)|go:"GO:0030317"(flagellated sperm motility)|go:"GO:0044853"(plasma membrane raft)|go:"GO:0046658"(anchored component of plasma membrane)|go:"GO:1901317"(regulation of flagellated sperm motility)|interpro:IPR016054(Ly-6 antigen / uPA receptor -like)|rcsb pdb:7BPR|reactome:R-HSA-163125|refseq:NP_001123483.1|refseq:NP_113639.4 refseq:NP_065910.3|ensembl:ENSG00000138771(gene)|ensembl:ENST00000296043(transcript)|go:"GO:0000902"(cell morphogenesis)|go:"GO:0001843"(neural tube closure)|go:"GO:0002064"(epithelial cell development)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005874"(microtubule)|go:"GO:0005912"(adherens junction)|go:"GO:0007015"(actin filament organization)|go:"GO:0007389"(pattern specification process)|go:"GO:0008360"(regulation of cell shape)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0030864"(cortical actin cytoskeleton)|go:"GO:0043296"(apical junction complex)|go:"GO:0043482"(cellular pigment accumulation)|go:"GO:0045176"(apical protein localization)|go:"GO:0051015"(actin filament binding)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR014799(Apx/shroom, ASD2)|interpro:IPR014800(Apx/shroom, ASD1)|interpro:IPR027685|interpro:IPR030494|interpro:IPR036034|mint:Q8TF72|rcsb pdb:6FBB|rcsb pdb:6FCP|ensembl:ENSP00000296043 - - - comment:"Proteins significantly enriched by immunoprecipitation with 34ED556 (T1) anti-TEX101 antibody in human sperm cells from pre-vasectomy semen samples."|figure legend:Fig. 2B, supplemental Table S6|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-spermatozoa)|taxid:9606(Homo sapiens) - 2020/03/24 2020/04/07 rogid:ZE4tXTFi7lUCcIbCL4KHzY3a6xM9606 rogid:0MpUunWh5c6Wwa8ep6BgurgU8e89606 rigid:TX1oljMyfkimcULEvhCJR/BRAW4 false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9BY14 uniprotkb:Q8TDB8 intact:EBI-12549378|ensembl:ENSP00000472769|uniprotkb:Q7L5R2|uniprotkb:Q9BPY7 intact:EBI-4289571|uniprotkb:Q6UY84|uniprotkb:B3KWW7|uniprotkb:B3KVB5|uniprotkb:Q8TDB9|uniprotkb:B7Z844|uniprotkb:B7ZAC3|ensembl:ENSP00000379834|ensembl:ENSP00000440480|ensembl:ENSP00000482927 psi-mi:tx101_human(display_long)|uniprotkb:TEX101(gene name)|psi-mi:TEX101(display_short)|uniprotkb:Cell surface receptor NYD-SP8(gene name synonym)|uniprotkb:SGRG(gene name synonym)|uniprotkb:Scleroderma-associated autoantigen(gene name synonym)|uniprotkb:Spermatogenesis-related gene protein(gene name synonym)|uniprotkb:UNQ867/PRO1884(orf name) psi-mi:gtr14_human(display_long)|uniprotkb:SLC2A14(gene name)|psi-mi:SLC2A14(display_short)|uniprotkb:GLUT14(gene name synonym)|uniprotkb:Glucose transporter type 14(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Schiza et al. (2018) imex:IM-28077|pubmed:30097533 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-25505396|imex:IM-28077-7 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000131126(gene)|ensembl:ENST00000598265(transcript)|go:"GO:0001669"(acrosomal vesicle)|go:"GO:0002080"(acrosomal membrane)|go:"GO:0005576"(extracellular region)|go:"GO:0005886"(plasma membrane)|go:"GO:0007339"(binding of sperm to zona pellucida)|go:"GO:0009566"(fertilization)|go:"GO:0030317"(flagellated sperm motility)|go:"GO:0044853"(plasma membrane raft)|go:"GO:0046658"(anchored component of plasma membrane)|go:"GO:1901317"(regulation of flagellated sperm motility)|interpro:IPR016054(Ly-6 antigen / uPA receptor -like)|rcsb pdb:7BPR|reactome:R-HSA-163125|refseq:NP_001123483.1|refseq:NP_113639.4 refseq:NP_001273162.1|refseq:NP_001273163.1|refseq:NP_001273164.1|refseq:NP_001273165.1|refseq:NP_001273166.1|refseq:NP_703150.1|refseq:XP_011518864.1|refseq:XP_011518865.1|refseq:XP_011518866.1|refseq:XP_011518867.1|refseq:XP_005253372.1|refseq:XP_005253374.1|refseq:XP_016874335.1|refseq:XP_016874336.1|go:"GO:0030154"(cell differentiation)|go:"GO:0033300"(dehydroascorbic acid transmembrane transporter activity)|go:"GO:0070837"(dehydroascorbic acid transport)|go:"GO:1904659"(glucose transmembrane transport)|interpro:IPR002945(Glucose transporter GLUT3, type 3)|interpro:IPR003663(Sugar transporter)|interpro:IPR005828(General substrate transporter)|interpro:IPR005829(Sugar transporter, conserved site)|interpro:IPR020846|interpro:IPR036259|reactome:R-HSA-189200|ensembl:ENSG00000173262(gene)|ensembl:ENST00000396589(transcript)|ensembl:ENST00000543909(transcript)|ensembl:ENST00000616981(transcript)|go:"GO:0005355"(glucose transmembrane transporter activity)|go:"GO:0005634"(nucleus)|go:"GO:0005886"(plasma membrane)|go:"GO:0007283"(spermatogenesis)|go:"GO:0016021"(integral component of membrane) - - - comment:"Proteins significantly enriched by immunoprecipitation with 34ED556 (T1) anti-TEX101 antibody in human sperm cells from pre-vasectomy semen samples."|figure legend:Fig. 2B, supplemental Table S6|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-spermatozoa)|taxid:9606(Homo sapiens) - 2020/03/24 2020/04/07 rogid:ZE4tXTFi7lUCcIbCL4KHzY3a6xM9606 rogid:mwGWT+WSWxgnzJNENfvZsFDCIPA9606 rigid:TX1oljMyfkimcULEvhCJR/BRAW4 false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9BY14 uniprotkb:P60709 intact:EBI-12549378|ensembl:ENSP00000472769|uniprotkb:Q7L5R2|uniprotkb:Q9BPY7 intact:EBI-353944|uniprotkb:P02570|uniprotkb:P70514|uniprotkb:P99021|uniprotkb:Q11211|uniprotkb:Q64316|uniprotkb:Q75MN2|uniprotkb:Q96B34|uniprotkb:Q96HG5|ensembl:ENSP00000494269|ensembl:ENSP00000494750|ensembl:ENSP00000495995|ensembl:ENSP00000501862|ensembl:ENSP00000502821 psi-mi:tx101_human(display_long)|uniprotkb:TEX101(gene name)|psi-mi:TEX101(display_short)|uniprotkb:Cell surface receptor NYD-SP8(gene name synonym)|uniprotkb:SGRG(gene name synonym)|uniprotkb:Scleroderma-associated autoantigen(gene name synonym)|uniprotkb:Spermatogenesis-related gene protein(gene name synonym)|uniprotkb:UNQ867/PRO1884(orf name) psi-mi:actb_human(display_long)|uniprotkb:ACTB(gene name)|psi-mi:ACTB(display_short)|uniprotkb:Beta-actin(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Schiza et al. (2018) imex:IM-28077|pubmed:30097533 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-25505396|imex:IM-28077-7 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000131126(gene)|ensembl:ENST00000598265(transcript)|go:"GO:0001669"(acrosomal vesicle)|go:"GO:0002080"(acrosomal membrane)|go:"GO:0005576"(extracellular region)|go:"GO:0005886"(plasma membrane)|go:"GO:0007339"(binding of sperm to zona pellucida)|go:"GO:0009566"(fertilization)|go:"GO:0030317"(flagellated sperm motility)|go:"GO:0044853"(plasma membrane raft)|go:"GO:0046658"(anchored component of plasma membrane)|go:"GO:1901317"(regulation of flagellated sperm motility)|interpro:IPR016054(Ly-6 antigen / uPA receptor -like)|rcsb pdb:7BPR|reactome:R-HSA-163125|refseq:NP_001123483.1|refseq:NP_113639.4 refseq:NP_001092.1|ensembl:ENSG00000075624(gene)|ensembl:ENST00000493945(transcript)|ensembl:ENST00000642480(transcript)|ensembl:ENST00000646664(transcript)|ensembl:ENST00000674681(transcript)|ensembl:ENST00000675515(transcript)|go:"GO:0000079"(regulation of cyclin-dependent protein serine/threonine kinase activity)|go:"GO:0000785"(chromatin)|go:"GO:0001738"(morphogenesis of a polarized epithelium)|go:"GO:0001895"(retina homeostasis)|go:"GO:0005200"(structural constituent of cytoskeleton)|go:"GO:0005524"(ATP binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005884"(actin filament)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005912"(adherens junction)|go:"GO:0005925"(focal adhesion)|go:"GO:0007163"(establishment or maintenance of cell polarity)|go:"GO:0007409"(axonogenesis)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0016020"(membrane)|go:"GO:0019894"(kinesin binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0021762"(substantia nigra development)|go:"GO:0022898"(regulation of transmembrane transporter activity)|go:"GO:0030027"(lamellipodium)|go:"GO:0030424"(axon)|go:"GO:0030863"(cortical cytoskeleton)|go:"GO:0030957"(Tat protein binding)|go:"GO:0031982"(vesicle)|go:"GO:0032091"(negative regulation of protein binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034333"(adherens junction assembly)|go:"GO:0035267"(NuA4 histone acetyltransferase complex)|go:"GO:0035633"(maintenance of blood-brain barrier)|go:"GO:0036464"(cytoplasmic ribonucleoprotein granule)|go:"GO:0042802"(identical protein binding)|go:"GO:0043044"|go:"GO:0043296"(apical junction complex)|go:"GO:0044305"(calyx of Held)|go:"GO:0045176"(apical protein localization)|go:"GO:0045202"(synapse)|go:"GO:0048156"(tau protein binding)|go:"GO:0048488"(synaptic vesicle endocytosis)|go:"GO:0048870"(cell motility)|go:"GO:0050998"(nitric-oxide synthase binding)|go:"GO:0051621"(regulation of norepinephrine uptake)|go:"GO:0051623"(positive regulation of norepinephrine uptake)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070160"(tight junction)|go:"GO:0070527"(platelet aggregation)|reactome:R-HSA-4420097|go:"GO:0071896"(protein localization to adherens junction)|go:"GO:0072562"(blood microparticle)|go:"GO:0072749"(cellular response to cytochalasin B)|go:"GO:0097433"(dense body)|go:"GO:0098685"(Schaffer collateral - CA1 synapse)|go:"GO:0098793"(presynapse)|go:"GO:0098871"(postsynaptic actin cytoskeleton)|go:"GO:0098973"(structural constituent of postsynaptic actin cytoskeleton)|go:"GO:0098974"(postsynaptic actin cytoskeleton organization)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0150111"(regulation of transepithelial transport)|go:"GO:1903076"(regulation of protein localization to plasma membrane)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR004000(Actin/actin-like)|interpro:IPR004001(Actin, conserved site)|interpro:IPR020902|interpro:IPR043129|mint:P60709|rcsb pdb:3BYH|rcsb pdb:3D2U|rcsb pdb:3J82|rcsb pdb:3LUE|rcsb pdb:6ANU|rcsb pdb:6ICT|rcsb pdb:6ICV|rcsb pdb:6LTJ|rcsb pdb:6MBJ|rcsb pdb:6MBK|rcsb pdb:6MBL|rcsb pdb:6NBW|rcsb pdb:6OX0|rcsb pdb:6OX1|rcsb pdb:6OX2|rcsb pdb:6OX3|rcsb pdb:6OX4|rcsb pdb:6OX5|rcsb pdb:6V62|rcsb pdb:6V63|rcsb pdb:6WK1|rcsb pdb:6WK2|rcsb pdb:7AS4|reactome:R-HSA-1445148|reactome:R-HSA-190873|reactome:R-HSA-196025|reactome:R-HSA-2029482|reactome:R-HSA-3214847|reactome:R-HSA-389957|reactome:R-HSA-390450|reactome:R-HSA-3928662|reactome:R-HSA-3928665|reactome:R-HSA-418990|reactome:R-HSA-437239|reactome:R-HSA-446353|reactome:R-HSA-5250924|reactome:R-HSA-5626467|reactome:R-HSA-5663213|reactome:R-HSA-5663220|reactome:R-HSA-5674135|reactome:R-HSA-5689603|reactome:R-HSA-5696394|reactome:R-HSA-6802946|reactome:R-HSA-6802948|reactome:R-HSA-6802952|reactome:R-HSA-6802955|reactome:R-HSA-8856828|reactome:R-HSA-9035034|reactome:R-HSA-9649948|reactome:R-HSA-9656223|reactome:R-HSA-9662360|reactome:R-HSA-9662361|reactome:R-HSA-9664422|reactome:R-HSA-983231|reactome:R-HSA-445095|dip:DIP-29686N - - - comment:"Proteins significantly enriched by immunoprecipitation with 34ED556 (T1) anti-TEX101 antibody in human sperm cells from pre-vasectomy semen samples."|figure legend:Fig. 2B, supplemental Table S6|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-spermatozoa)|taxid:9606(Homo sapiens) - 2020/03/24 2020/04/07 rogid:ZE4tXTFi7lUCcIbCL4KHzY3a6xM9606 rogid:Hoge1B8Pn56kvbNTpkSLsQuHwRc9606 rigid:TX1oljMyfkimcULEvhCJR/BRAW4 false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9BY14 uniprotkb:P00338 intact:EBI-12549378|ensembl:ENSP00000472769|uniprotkb:Q7L5R2|uniprotkb:Q9BPY7 intact:EBI-372327|uniprotkb:Q53G53|uniprotkb:Q6IBM7|uniprotkb:Q6ZNV1|ensembl:ENSP00000368722|ensembl:ENSP00000395337|ensembl:ENSP00000445331|ensembl:ENSP00000499898|ensembl:ENSP00000499977|ensembl:ENSP00000500953|uniprotkb:Q9UDE8|uniprotkb:Q9UDE9|uniprotkb:D3DQY3|uniprotkb:B7Z5E3|uniprotkb:B4DKQ2|uniprotkb:F8W819 psi-mi:tx101_human(display_long)|uniprotkb:TEX101(gene name)|psi-mi:TEX101(display_short)|uniprotkb:Cell surface receptor NYD-SP8(gene name synonym)|uniprotkb:SGRG(gene name synonym)|uniprotkb:Scleroderma-associated autoantigen(gene name synonym)|uniprotkb:Spermatogenesis-related gene protein(gene name synonym)|uniprotkb:UNQ867/PRO1884(orf name) psi-mi:ldha_human(display_long)|uniprotkb:LDHA(gene name)|psi-mi:LDHA(display_short)|uniprotkb:LDH muscle subunit(gene name synonym)|uniprotkb:Renal carcinoma antigen NY-REN-59(gene name synonym)|uniprotkb:Cell proliferation-inducing gene 19 protein(gene name synonym)|uniprotkb:PIG19(orf name) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Schiza et al. (2018) imex:IM-28077|pubmed:30097533 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-25505396|imex:IM-28077-7 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000131126(gene)|ensembl:ENST00000598265(transcript)|go:"GO:0001669"(acrosomal vesicle)|go:"GO:0002080"(acrosomal membrane)|go:"GO:0005576"(extracellular region)|go:"GO:0005886"(plasma membrane)|go:"GO:0007339"(binding of sperm to zona pellucida)|go:"GO:0009566"(fertilization)|go:"GO:0030317"(flagellated sperm motility)|go:"GO:0044853"(plasma membrane raft)|go:"GO:0046658"(anchored component of plasma membrane)|go:"GO:1901317"(regulation of flagellated sperm motility)|interpro:IPR016054(Ly-6 antigen / uPA receptor -like)|rcsb pdb:7BPR|reactome:R-HSA-163125|refseq:NP_001123483.1|refseq:NP_113639.4 refseq:NP_001158886.1|ensembl:ENSG00000134333(gene)|ensembl:ENSG00000288299(gene)|ensembl:ENST00000379412(transcript)|ensembl:ENST00000422447(transcript)|ensembl:ENST00000542179(transcript)|ensembl:ENST00000671981(transcript)|ensembl:ENST00000672405(transcript)|ensembl:ENST00000673204(transcript)|go:"GO:0001666"(response to hypoxia)|go:"GO:0004459"(L-lactate dehydrogenase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0006089"(lactate metabolic process)|go:"GO:0006096"(glycolytic process)|go:"GO:0007584"(response to nutrient)|go:"GO:0009749"(response to glucose)|go:"GO:0016020"(membrane)|go:"GO:0019674"(NAD metabolic process)|go:"GO:0019900"(kinase binding)|go:"GO:0021762"(substantia nigra development)|go:"GO:0042493"|go:"GO:0042542"(response to hydrogen peroxide)|go:"GO:0042802"(identical protein binding)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043627"(response to estrogen)|go:"GO:0045296"(cadherin binding)|go:"GO:0048569"(post-embryonic animal organ development)|go:"GO:0051287"(NAD binding)|go:"GO:0051591"(response to cAMP)|go:"GO:0070062"(extracellular exosome)|interpro:IPR001236(Lactate/malate dehydrogenase)|interpro:IPR001557(L-lactate/malate dehydrogenase)|interpro:IPR011304(L-lactate dehydrogenase)|interpro:IPR015955(Lactate dehydrogenase/glycoside hydrolase, family 4, C-terminal)|interpro:IPR018177|interpro:IPR022383|interpro:IPR036291|rcsb pdb:1I10|mint:P00338|rcsb pdb:4AJP|rcsb pdb:4JNK|rcsb pdb:4L4R|rcsb pdb:4L4S|rcsb pdb:4M49|rcsb pdb:4OJN|rcsb pdb:4OKN|rcsb pdb:4QO7|rcsb pdb:4QO8|rcsb pdb:4QSM|rcsb pdb:4QT0|rcsb pdb:4R68|rcsb pdb:4R69|rcsb pdb:4RLS|rcsb pdb:4ZVV|rcsb pdb:5IXS|rcsb pdb:5IXY|rcsb pdb:5W8H|rcsb pdb:5W8I|rcsb pdb:5W8J|rcsb pdb:5W8K|rcsb pdb:5W8L|rcsb pdb:5ZJD|rcsb pdb:5ZJE|rcsb pdb:5ZJF|rcsb pdb:6BAD|rcsb pdb:6BAG|rcsb pdb:6BAX|rcsb pdb:6BAZ|rcsb pdb:6BB0|rcsb pdb:6BB1|rcsb pdb:6BB2|rcsb pdb:6BB3|rcsb pdb:6MV8|rcsb pdb:6MVA|rcsb pdb:6Q0D|rcsb pdb:6SBU|rcsb pdb:6SBV|rcsb pdb:6ZZR|reactome:R-HSA-70268|rcsb pdb:6Q13|refseq:NP_001158887.1|refseq:NP_005557.1|refseq:NP_001128711.1|refseq:NP_001158888.1 - - - comment:"Proteins significantly enriched by immunoprecipitation with 34ED556 (T1) anti-TEX101 antibody in human sperm cells from pre-vasectomy semen samples."|figure legend:Fig. 2B, supplemental Table S6|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-spermatozoa)|taxid:9606(Homo sapiens) - 2020/03/24 2020/04/07 rogid:ZE4tXTFi7lUCcIbCL4KHzY3a6xM9606 rogid:Zpq2lAJLPG+q2bMEru3cq7B5gCk9606 rigid:TX1oljMyfkimcULEvhCJR/BRAW4 false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9BY14 uniprotkb:P50991 intact:EBI-12549378|ensembl:ENSP00000472769|uniprotkb:Q7L5R2|uniprotkb:Q9BPY7 intact:EBI-356876|uniprotkb:O14870|uniprotkb:Q96C51|uniprotkb:Q53QP9|uniprotkb:B2R6I3|uniprotkb:B7Z8B1|uniprotkb:F5H5W3|ensembl:ENSP00000377958 psi-mi:tx101_human(display_long)|uniprotkb:TEX101(gene name)|psi-mi:TEX101(display_short)|uniprotkb:Cell surface receptor NYD-SP8(gene name synonym)|uniprotkb:SGRG(gene name synonym)|uniprotkb:Scleroderma-associated autoantigen(gene name synonym)|uniprotkb:Spermatogenesis-related gene protein(gene name synonym)|uniprotkb:UNQ867/PRO1884(orf name) psi-mi:tcpd_human(display_long)|uniprotkb:CCT4(gene name)|psi-mi:CCT4(display_short)|uniprotkb:CCTD(gene name synonym)|uniprotkb:SRB(gene name synonym)|uniprotkb:CCT-delta(gene name synonym)|uniprotkb:Stimulator of TAR RNA-binding(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Schiza et al. (2018) imex:IM-28077|pubmed:30097533 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-25505396|imex:IM-28077-7 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000131126(gene)|ensembl:ENST00000598265(transcript)|go:"GO:0001669"(acrosomal vesicle)|go:"GO:0002080"(acrosomal membrane)|go:"GO:0005576"(extracellular region)|go:"GO:0005886"(plasma membrane)|go:"GO:0007339"(binding of sperm to zona pellucida)|go:"GO:0009566"(fertilization)|go:"GO:0030317"(flagellated sperm motility)|go:"GO:0044853"(plasma membrane raft)|go:"GO:0046658"(anchored component of plasma membrane)|go:"GO:1901317"(regulation of flagellated sperm motility)|interpro:IPR016054(Ly-6 antigen / uPA receptor -like)|rcsb pdb:7BPR|reactome:R-HSA-163125|refseq:NP_001123483.1|refseq:NP_113639.4 refseq:NP_006421.2|refseq:NP_001243650.1|dip:DIP-32971N|ensembl:ENSG00000115484(gene)|ensembl:ENST00000394440(transcript)|go:"GO:0002199"(zona pellucida receptor complex)|go:"GO:0003723"(RNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005832"(chaperonin-containing T-complex)|go:"GO:0005874"(microtubule)|go:"GO:0006457"(protein folding)|go:"GO:0007339"(binding of sperm to zona pellucida)|go:"GO:0032212"(positive regulation of telomere maintenance via telomerase)|go:"GO:0042470"(melanosome)|go:"GO:0042995"(cell projection)|go:"GO:0044183"(protein folding chaperone)|go:"GO:0044297"(cell body)|go:"GO:0050821"(protein stabilization)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0051973"(positive regulation of telomerase activity)|go:"GO:0070062"(extracellular exosome)|go:"GO:0090666"(scaRNA localization to Cajal body)|go:"GO:1901998"(toxin transport)|go:"GO:1904851"(positive regulation of establishment of protein localization to telomere)|go:"GO:1904871"(positive regulation of protein localization to Cajal body)|go:"GO:1904874"(positive regulation of telomerase RNA localization to Cajal body)|interpro:IPR002194(Chaperonin TCP-1, conserved site)|interpro:IPR002423(Chaperonin Cpn60/TCP-1)|interpro:IPR012717(T-complex protein 1, delta subunit)|interpro:IPR027409|interpro:IPR027410|interpro:IPR027413|mint:P50991|rcsb pdb:6NR8|rcsb pdb:6NR9|rcsb pdb:6NRA|rcsb pdb:6NRB|rcsb pdb:6NRC|rcsb pdb:6NRD|rcsb pdb:6QB8|rcsb pdb:7LUM|rcsb pdb:7LUP|reactome:R-HSA-389957|reactome:R-HSA-389960|reactome:R-HSA-390450|reactome:R-HSA-390471|reactome:R-HSA-5620922|reactome:R-HSA-6814122|interpro:IPR017998 - - - comment:"Proteins significantly enriched by immunoprecipitation with 34ED556 (T1) anti-TEX101 antibody in human sperm cells from pre-vasectomy semen samples."|figure legend:Fig. 2B, supplemental Table S6|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-spermatozoa)|taxid:9606(Homo sapiens) - 2020/03/24 2020/04/07 rogid:ZE4tXTFi7lUCcIbCL4KHzY3a6xM9606 rogid:Erg8Zzajt1WbrByS9LR4NAhZrXM9606 rigid:TX1oljMyfkimcULEvhCJR/BRAW4 false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9BY14 uniprotkb:P01034 intact:EBI-12549378|ensembl:ENSP00000472769|uniprotkb:Q7L5R2|uniprotkb:Q9BPY7 intact:EBI-948622|ensembl:ENSP00000366124|ensembl:ENSP00000381446|ensembl:ENSP00000381448|uniprotkb:Q6FGW9|uniprotkb:B2R5J9|uniprotkb:D3DW42 psi-mi:tx101_human(display_long)|uniprotkb:TEX101(gene name)|psi-mi:TEX101(display_short)|uniprotkb:Cell surface receptor NYD-SP8(gene name synonym)|uniprotkb:SGRG(gene name synonym)|uniprotkb:Scleroderma-associated autoantigen(gene name synonym)|uniprotkb:Spermatogenesis-related gene protein(gene name synonym)|uniprotkb:UNQ867/PRO1884(orf name) psi-mi:cytc_human(display_long)|uniprotkb:Cystatin-3(gene name synonym)|uniprotkb:Neuroendocrine basic polypeptide(gene name synonym)|uniprotkb:Gamma-trace(gene name synonym)|uniprotkb:Post-gamma-globulin(gene name synonym)|uniprotkb:CST3(gene name)|psi-mi:CST3(display_short) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Schiza et al. (2018) imex:IM-28077|pubmed:30097533 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-25505396|imex:IM-28077-7 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000131126(gene)|ensembl:ENST00000598265(transcript)|go:"GO:0001669"(acrosomal vesicle)|go:"GO:0002080"(acrosomal membrane)|go:"GO:0005576"(extracellular region)|go:"GO:0005886"(plasma membrane)|go:"GO:0007339"(binding of sperm to zona pellucida)|go:"GO:0009566"(fertilization)|go:"GO:0030317"(flagellated sperm motility)|go:"GO:0044853"(plasma membrane raft)|go:"GO:0046658"(anchored component of plasma membrane)|go:"GO:1901317"(regulation of flagellated sperm motility)|interpro:IPR016054(Ly-6 antigen / uPA receptor -like)|rcsb pdb:7BPR|reactome:R-HSA-163125|refseq:NP_001123483.1|refseq:NP_113639.4 go:"GO:0060313"(negative regulation of blood vessel remodeling)|go:"GO:0070062"(extracellular exosome)|go:"GO:0097435"(supramolecular fiber organization)|go:"GO:1904724"(tertiary granule lumen)|go:"GO:1904813"(ficolin-1-rich granule lumen)|interpro:IPR000010(Proteinase inhibitor I25, cystatin)|interpro:IPR018073|rcsb pdb:1G96|rcsb pdb:1R4C|rcsb pdb:1TIJ|rcsb pdb:3GAX|rcsb pdb:3NX0|rcsb pdb:3PS8|rcsb pdb:3QRD|rcsb pdb:3S67|rcsb pdb:3SVA|rcsb pdb:6ROA|rcsb pdb:6RPV|reactome:R-HSA-381426|reactome:R-HSA-6798695|reactome:R-HSA-8957275|reactome:R-HSA-977225|ensembl:ENSG00000101439(gene)|ensembl:ENST00000376925(transcript)|ensembl:ENST00000398409(transcript)|ensembl:ENST00000398411(transcript)|go:"GO:0001540"(amyloid-beta binding)|go:"GO:0002020"(protease binding)|go:"GO:0004866"(endopeptidase inhibitor activity)|go:"GO:0004869"(cysteine-type endopeptidase inhibitor activity)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005788"(endoplasmic reticulum lumen)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0006952"(defense response)|go:"GO:0010466"(negative regulation of peptidase activity)|go:"GO:0010711"(negative regulation of collagen catabolic process)|go:"GO:0010716"(negative regulation of extracellular matrix disassembly)|go:"GO:0030414"(peptidase inhibitor activity)|go:"GO:0034103"(regulation of tissue remodeling)|go:"GO:0042802"(identical protein binding)|go:"GO:0045861"(negative regulation of proteolysis)|go:"GO:0060311"(negative regulation of elastin catabolic process)|refseq:NP_000090.1|refseq:NP_001275543.1 - - - comment:"Proteins significantly enriched by immunoprecipitation with 34ED556 (T1) anti-TEX101 antibody in human sperm cells from pre-vasectomy semen samples."|figure legend:Fig. 2B, supplemental Table S6|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-spermatozoa)|taxid:9606(Homo sapiens) - 2020/03/24 2020/04/07 rogid:ZE4tXTFi7lUCcIbCL4KHzY3a6xM9606 rogid:UJT8nc0DeqGBXeRiy8RnrB1tKGw9606 rigid:TX1oljMyfkimcULEvhCJR/BRAW4 false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9BY14 uniprotkb:O00194 intact:EBI-12549378|ensembl:ENSP00000472769|uniprotkb:Q7L5R2|uniprotkb:Q9BPY7 intact:EBI-10179046|uniprotkb:Q9BZB6|uniprotkb:B2RAB0|ensembl:ENSP00000262094 psi-mi:tx101_human(display_long)|uniprotkb:TEX101(gene name)|psi-mi:TEX101(display_short)|uniprotkb:Cell surface receptor NYD-SP8(gene name synonym)|uniprotkb:SGRG(gene name synonym)|uniprotkb:Scleroderma-associated autoantigen(gene name synonym)|uniprotkb:Spermatogenesis-related gene protein(gene name synonym)|uniprotkb:UNQ867/PRO1884(orf name) psi-mi:rb27b_human(display_long)|uniprotkb:RAB27B(gene name)|psi-mi:RAB27B(display_short)|uniprotkb:C25KG(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Schiza et al. (2018) imex:IM-28077|pubmed:30097533 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-25505396|imex:IM-28077-7 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000131126(gene)|ensembl:ENST00000598265(transcript)|go:"GO:0001669"(acrosomal vesicle)|go:"GO:0002080"(acrosomal membrane)|go:"GO:0005576"(extracellular region)|go:"GO:0005886"(plasma membrane)|go:"GO:0007339"(binding of sperm to zona pellucida)|go:"GO:0009566"(fertilization)|go:"GO:0030317"(flagellated sperm motility)|go:"GO:0044853"(plasma membrane raft)|go:"GO:0046658"(anchored component of plasma membrane)|go:"GO:1901317"(regulation of flagellated sperm motility)|interpro:IPR016054(Ly-6 antigen / uPA receptor -like)|rcsb pdb:7BPR|reactome:R-HSA-163125|refseq:NP_001123483.1|refseq:NP_113639.4 refseq:NP_004154.2|refseq:XP_005266790.1|refseq:XP_016881402.1|refseq:XP_016881403.1|ensembl:ENSG00000041353(gene)|ensembl:ENST00000262094(transcript)|go:"GO:0003924"(GTPase activity)|go:"GO:0003925"(G protein activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005770"(late endosome)|go:"GO:0005795"(Golgi stack)|go:"GO:0005886"(plasma membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0019003"(GDP binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030140"(trans-Golgi network transport vesicle)|go:"GO:0030141"(secretory granule)|go:"GO:0031088"(platelet dense granule membrane)|go:"GO:0031489"(myosin V binding)|go:"GO:0032402"(melanosome transport)|go:"GO:0032585"(multivesicular body membrane)|go:"GO:0042470"(melanosome)|go:"GO:0042589"(zymogen granule membrane)|go:"GO:0045921"(positive regulation of exocytosis)|go:"GO:0048488"(synaptic vesicle endocytosis)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071985"(multivesicular body sorting pathway)|go:"GO:0098993"(anchored component of synaptic vesicle membrane)|go:"GO:0099641"(anterograde axonal protein transport)|go:"GO:1904115"(axon cytoplasm)|interpro:IPR001806(Ras GTPase)|interpro:IPR005225(Small GTP-binding protein)|interpro:IPR027417|interpro:IPR041837|rcsb pdb:2F7S|reactome:R-HSA-114608|reactome:R-HSA-8873719|reactome:R-HSA-8876198|dip:DIP-48948N - - - comment:"Proteins significantly enriched by immunoprecipitation with 34ED556 (T1) anti-TEX101 antibody in human sperm cells from pre-vasectomy semen samples."|figure legend:Fig. 2B, supplemental Table S6|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-spermatozoa)|taxid:9606(Homo sapiens) - 2020/03/24 2020/04/07 rogid:ZE4tXTFi7lUCcIbCL4KHzY3a6xM9606 rogid:3+RN6+dvBCVI/SDuGKZIrxr0L/49606 rigid:TX1oljMyfkimcULEvhCJR/BRAW4 false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9BY14 uniprotkb:P08574 intact:EBI-12549378|ensembl:ENSP00000472769|uniprotkb:Q7L5R2|uniprotkb:Q9BPY7 intact:EBI-1224514|uniprotkb:Q5U062|uniprotkb:Q6FHS7|ensembl:ENSP00000317159 psi-mi:tx101_human(display_long)|uniprotkb:TEX101(gene name)|psi-mi:TEX101(display_short)|uniprotkb:Cell surface receptor NYD-SP8(gene name synonym)|uniprotkb:SGRG(gene name synonym)|uniprotkb:Scleroderma-associated autoantigen(gene name synonym)|uniprotkb:Spermatogenesis-related gene protein(gene name synonym)|uniprotkb:UNQ867/PRO1884(orf name) psi-mi:cy1_human(display_long)|uniprotkb:CYC1(gene name)|psi-mi:CYC1(display_short)|uniprotkb:Ubiquinol-cytochrome-c reductase complex cytochrome c1 subunit(gene name synonym)|uniprotkb:Cytochrome b-c1 complex subunit 4(gene name synonym)|uniprotkb:Complex III subunit 4(gene name synonym)|uniprotkb:Complex III subunit IV(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Schiza et al. (2018) imex:IM-28077|pubmed:30097533 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-25505396|imex:IM-28077-7 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000131126(gene)|ensembl:ENST00000598265(transcript)|go:"GO:0001669"(acrosomal vesicle)|go:"GO:0002080"(acrosomal membrane)|go:"GO:0005576"(extracellular region)|go:"GO:0005886"(plasma membrane)|go:"GO:0007339"(binding of sperm to zona pellucida)|go:"GO:0009566"(fertilization)|go:"GO:0030317"(flagellated sperm motility)|go:"GO:0044853"(plasma membrane raft)|go:"GO:0046658"(anchored component of plasma membrane)|go:"GO:1901317"(regulation of flagellated sperm motility)|interpro:IPR016054(Ly-6 antigen / uPA receptor -like)|rcsb pdb:7BPR|reactome:R-HSA-163125|refseq:NP_001123483.1|refseq:NP_113639.4 refseq:NP_001907.2|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005750"(mitochondrial respiratory chain complex III)|go:"GO:0006122"(mitochondrial electron transport, ubiquinol to cytochrome c)|go:"GO:0008121"(ubiquinol-cytochrome-c reductase activity)|go:"GO:0016020"(membrane)|go:"GO:0020037"(heme binding)|go:"GO:0033762"(response to glucagon)|go:"GO:0046872"(metal ion binding)|interpro:IPR002326(Cytochrome c1)|interpro:IPR021157|interpro:IPR036909|mint:P08574|rcsb pdb:5XTE|rcsb pdb:5XTH|rcsb pdb:5XTI|reactome:R-HSA-1268020|reactome:R-HSA-611105|ensembl:ENSG00000179091(gene)|ensembl:ENST00000318911(transcript)|go:"GO:0005634"(nucleus) - - - comment:"Proteins significantly enriched by immunoprecipitation with 34ED556 (T1) anti-TEX101 antibody in human sperm cells from pre-vasectomy semen samples."|figure legend:Fig. 2B, supplemental Table S6|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-spermatozoa)|taxid:9606(Homo sapiens) - 2020/03/24 2020/04/07 rogid:ZE4tXTFi7lUCcIbCL4KHzY3a6xM9606 rogid:WFFFejEobb6Uoum311x+fry5X+o9606 rigid:TX1oljMyfkimcULEvhCJR/BRAW4 false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9BY14 uniprotkb:P28907 intact:EBI-12549378|ensembl:ENSP00000472769|uniprotkb:Q7L5R2|uniprotkb:Q9BPY7 intact:EBI-25505481|ensembl:ENSP00000226279|uniprotkb:O00121|uniprotkb:O00122|uniprotkb:Q96HY4 psi-mi:tx101_human(display_long)|uniprotkb:TEX101(gene name)|psi-mi:TEX101(display_short)|uniprotkb:Cell surface receptor NYD-SP8(gene name synonym)|uniprotkb:SGRG(gene name synonym)|uniprotkb:Scleroderma-associated autoantigen(gene name synonym)|uniprotkb:Spermatogenesis-related gene protein(gene name synonym)|uniprotkb:UNQ867/PRO1884(orf name) psi-mi:cd38_human(display_long)|uniprotkb:CD38(gene name)|psi-mi:CD38(display_short)|uniprotkb:2'-phospho-ADP-ribosyl cyclase(gene name synonym)|uniprotkb:2'-phospho-ADP-ribosyl cyclase/2'-phospho-cyclic-ADP-ribose transferase(gene name synonym)|uniprotkb:2'-phospho-cyclic-ADP-ribose transferase(gene name synonym)|uniprotkb:ADP-ribosyl cyclase 1(gene name synonym)|uniprotkb:Cyclic ADP-ribose hydrolase 1(gene name synonym)|uniprotkb:T10(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Schiza et al. (2018) imex:IM-28077|pubmed:30097533 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-25505396|imex:IM-28077-7 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000131126(gene)|ensembl:ENST00000598265(transcript)|go:"GO:0001669"(acrosomal vesicle)|go:"GO:0002080"(acrosomal membrane)|go:"GO:0005576"(extracellular region)|go:"GO:0005886"(plasma membrane)|go:"GO:0007339"(binding of sperm to zona pellucida)|go:"GO:0009566"(fertilization)|go:"GO:0030317"(flagellated sperm motility)|go:"GO:0044853"(plasma membrane raft)|go:"GO:0046658"(anchored component of plasma membrane)|go:"GO:1901317"(regulation of flagellated sperm motility)|interpro:IPR016054(Ly-6 antigen / uPA receptor -like)|rcsb pdb:7BPR|reactome:R-HSA-163125|refseq:NP_001123483.1|refseq:NP_113639.4 go:"GO:0030307"(positive regulation of cell growth)|go:"GO:0030667"(secretory granule membrane)|go:"GO:0030890"(positive regulation of B cell proliferation)|go:"GO:0032024"(positive regulation of insulin secretion)|go:"GO:0032355"(response to estradiol)|go:"GO:0032526"(response to retinoic acid)|go:"GO:0032570"(response to progesterone)|go:"GO:0033194"(response to hydroperoxide)|go:"GO:0042493"|go:"GO:0042802"(identical protein binding)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0045779"(negative regulation of bone resorption)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045907"(positive regulation of vasoconstriction)|go:"GO:0050135"("NAD(P)+ nucleosidase activity")|go:"GO:0050853"(B cell receptor signaling pathway)|go:"GO:0060292"(long-term synaptic depression)|go:"GO:0061809"(NAD+ nucleotidase, cyclic ADP-ribose generating)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070555"(response to interleukin-1)|go:"GO:0097190"(apoptotic signaling pathway)|interpro:IPR003193("ADP-ribosyl cyclase (CD38/157)")|interpro:IPR033567|rcsb pdb:1YH3|rcsb pdb:1ZVM|rcsb pdb:2EF1|rcsb pdb:2HCT|rcsb pdb:2I65|rcsb pdb:2I67|rcsb pdb:2O3Q|rcsb pdb:2O3R|rcsb pdb:2O3S|rcsb pdb:2O3T|rcsb pdb:2O3U|rcsb pdb:2PGJ|rcsb pdb:2PGL|rcsb pdb:3DZF|rcsb pdb:3DZG|rcsb pdb:3DZH|rcsb pdb:3DZI|rcsb pdb:2I66|rcsb pdb:3DZJ|rcsb pdb:3DZK|rcsb pdb:3F6Y|rcsb pdb:3I9M|rcsb pdb:3I9N|rcsb pdb:3OFS|rcsb pdb:3RAJ|rcsb pdb:3ROK|rcsb pdb:3ROM|rcsb pdb:3ROP|rcsb pdb:3ROQ|rcsb pdb:3U4H|rcsb pdb:3U4I|rcsb pdb:4CMH|rcsb pdb:4F45|rcsb pdb:4F46|rcsb pdb:4OGW|rcsb pdb:4TMF|rcsb pdb:4XJS|rcsb pdb:4XJT|rcsb pdb:5F1K|rcsb pdb:5F21|rcsb pdb:6EDR|rcsb pdb:6VUA|rcsb pdb:7DUO|reactome:R-HSA-196807|rcsb pdb:5F1O|ensembl:ENSG00000004468(gene)|ensembl:ENST00000226279(transcript)|go:"GO:0001666"(response to hypoxia)|go:"GO:0003953"(NAD+ nucleosidase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005886"(plasma membrane)|go:"GO:0007165"(signal transduction)|go:"GO:0007204"(positive regulation of cytosolic calcium ion concentration)|go:"GO:0007565"(female pregnancy)|go:"GO:0009986"(cell surface)|go:"GO:0010977"(negative regulation of neuron projection development)|go:"GO:0014824"(artery smooth muscle contraction)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016740"(transferase activity)|go:"GO:0016849"(phosphorus-oxygen lyase activity)|go:"GO:0019674"(NAD metabolic process)|refseq:NP_001766.2 - - - comment:"Proteins significantly enriched by immunoprecipitation with 34ED556 (T1) anti-TEX101 antibody in human sperm cells from pre-vasectomy semen samples."|figure legend:Fig. 2B, supplemental Table S6|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-spermatozoa)|taxid:9606(Homo sapiens) - 2020/03/24 2020/04/07 rogid:ZE4tXTFi7lUCcIbCL4KHzY3a6xM9606 rogid:gQaSmb4SjV25/EE7RnwHevZJkk89606 rigid:TX1oljMyfkimcULEvhCJR/BRAW4 false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9BY14 uniprotkb:Q14974 intact:EBI-12549378|ensembl:ENSP00000472769|uniprotkb:Q7L5R2|uniprotkb:Q9BPY7 intact:EBI-286758|uniprotkb:Q14637|uniprotkb:Q96J27|uniprotkb:Q53XN2|uniprotkb:B7ZAV6|uniprotkb:D3DTT3|intact:EBI-28976864|ensembl:ENSP00000290158|ensembl:ENSP00000464042 psi-mi:tx101_human(display_long)|uniprotkb:TEX101(gene name)|psi-mi:TEX101(display_short)|uniprotkb:Cell surface receptor NYD-SP8(gene name synonym)|uniprotkb:SGRG(gene name synonym)|uniprotkb:Scleroderma-associated autoantigen(gene name synonym)|uniprotkb:Spermatogenesis-related gene protein(gene name synonym)|uniprotkb:UNQ867/PRO1884(orf name) psi-mi:imb1_human(display_long)|uniprotkb:Karyopherin subunit beta-1(gene name synonym)|uniprotkb:Nuclear factor p97(gene name synonym)|uniprotkb:Importin-90(gene name synonym)|uniprotkb:KPNB1(gene name)|psi-mi:KPNB1(display_short)|uniprotkb:NTF97(gene name synonym)|uniprotkb:Pore targeting complex 97 kDa subunit(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Schiza et al. (2018) imex:IM-28077|pubmed:30097533 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-25505396|imex:IM-28077-7 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000131126(gene)|ensembl:ENST00000598265(transcript)|go:"GO:0001669"(acrosomal vesicle)|go:"GO:0002080"(acrosomal membrane)|go:"GO:0005576"(extracellular region)|go:"GO:0005886"(plasma membrane)|go:"GO:0007339"(binding of sperm to zona pellucida)|go:"GO:0009566"(fertilization)|go:"GO:0030317"(flagellated sperm motility)|go:"GO:0044853"(plasma membrane raft)|go:"GO:0046658"(anchored component of plasma membrane)|go:"GO:1901317"(regulation of flagellated sperm motility)|interpro:IPR016054(Ly-6 antigen / uPA receptor -like)|rcsb pdb:7BPR|reactome:R-HSA-163125|refseq:NP_001123483.1|refseq:NP_113639.4 ensembl:ENSP00000290158|ensembl:ENST00000535458|ensembl:ENSP00000438253|ensembl:ENST00000540627|ensembl:ENSP00000438964|ensembl:ENSP00000464042|refseq:NP_002256.2|refseq:NP_001263382.1|dip:DIP-6204N|ensembl:ENSG00000108424(gene)|ensembl:ENST00000290158(transcript)|ensembl:ENST00000583648(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005634"(nucleus)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005643"(nuclear pore)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0006607"(NLS-bearing protein import into nucleus)|go:"GO:0006610"(ribosomal protein import into nucleus)|go:"GO:0007079"(mitotic chromosome movement towards spindle pole)|go:"GO:0007080"(mitotic metaphase plate congression)|go:"GO:0008139"(nuclear localization sequence binding)|go:"GO:0008270"(zinc ion binding)|go:"GO:0010494"(cytoplasmic stress granule)|go:"GO:0016020"(membrane)|go:"GO:0019899"(enzyme binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030953"(astral microtubule organization)|go:"GO:0031267"(small GTPase binding)|go:"GO:0031291"(Ran protein signal transduction)|go:"GO:0031965"(nuclear membrane)|go:"GO:0035580"(specific granule lumen)|go:"GO:0040001"(establishment of mitotic spindle localization)|go:"GO:0045184"(establishment of protein localization)|go:"GO:0051879"(Hsp90 protein binding)|go:"GO:0061608"(nuclear import signal receptor activity)|go:"GO:0061676"(importin-alpha family protein binding)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071782"(endoplasmic reticulum tubular network)|go:"GO:0090307"(mitotic spindle assembly)|go:"GO:1904813"(ficolin-1-rich granule lumen)|interpro:IPR000225(Armadillo)|interpro:IPR001494(Importin-beta, N-terminal)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR021133|interpro:IPR040122|mint:Q14974|rcsb pdb:1F59|rcsb pdb:1IBR|rcsb pdb:1M5N|rcsb pdb:1O6O|rcsb pdb:1O6P|rcsb pdb:1QGK|rcsb pdb:1QGR|rcsb pdb:2P8Q|rcsb pdb:2Q5D|rcsb pdb:2QNA|rcsb pdb:3LWW|rcsb pdb:3W5K|rcsb pdb:6N88|rcsb pdb:6N89|reactome:R-HSA-1169408|reactome:R-HSA-140342|reactome:R-HSA-1655829|reactome:R-HSA-168271|reactome:R-HSA-168276|reactome:R-HSA-180746|reactome:R-HSA-2995383|reactome:R-HSA-6798695|reactome:R-HSA-909733|reactome:R-HSA-9615933|reactome:R-HSA-9636249 - - - comment:"Proteins significantly enriched by immunoprecipitation with 34ED556 (T1) anti-TEX101 antibody in human sperm cells from pre-vasectomy semen samples."|figure legend:Fig. 2B, supplemental Table S6|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-spermatozoa)|taxid:9606(Homo sapiens) - 2020/03/24 2020/04/07 rogid:ZE4tXTFi7lUCcIbCL4KHzY3a6xM9606 rogid:8NbS9qoyCx+M+X3KOe1+PQ3oSYk9606 rigid:TX1oljMyfkimcULEvhCJR/BRAW4 false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9BY14 uniprotkb:P16499 intact:EBI-12549378|ensembl:ENSP00000472769|uniprotkb:Q7L5R2|uniprotkb:Q9BPY7 intact:EBI-25505448|ensembl:ENSP00000255266|uniprotkb:Q0P638 psi-mi:tx101_human(display_long)|uniprotkb:TEX101(gene name)|psi-mi:TEX101(display_short)|uniprotkb:Cell surface receptor NYD-SP8(gene name synonym)|uniprotkb:SGRG(gene name synonym)|uniprotkb:Scleroderma-associated autoantigen(gene name synonym)|uniprotkb:Spermatogenesis-related gene protein(gene name synonym)|uniprotkb:UNQ867/PRO1884(orf name) psi-mi:pde6a_human(display_long)|uniprotkb:PDE6A(gene name)|psi-mi:PDE6A(display_short)|uniprotkb:PDEA(gene name synonym)|uniprotkb:PDE V-B1(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Schiza et al. (2018) imex:IM-28077|pubmed:30097533 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-25505396|imex:IM-28077-7 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000131126(gene)|ensembl:ENST00000598265(transcript)|go:"GO:0001669"(acrosomal vesicle)|go:"GO:0002080"(acrosomal membrane)|go:"GO:0005576"(extracellular region)|go:"GO:0005886"(plasma membrane)|go:"GO:0007339"(binding of sperm to zona pellucida)|go:"GO:0009566"(fertilization)|go:"GO:0030317"(flagellated sperm motility)|go:"GO:0044853"(plasma membrane raft)|go:"GO:0046658"(anchored component of plasma membrane)|go:"GO:1901317"(regulation of flagellated sperm motility)|interpro:IPR016054(Ly-6 antigen / uPA receptor -like)|rcsb pdb:7BPR|reactome:R-HSA-163125|refseq:NP_001123483.1|refseq:NP_113639.4 ensembl:ENSP00000255266|ensembl:ENSG00000132915(gene)|ensembl:ENST00000255266(transcript)|go:"GO:0004114"(3',5'-cyclic-nucleotide phosphodiesterase activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0007165"(signal transduction)|go:"GO:0007601"(visual perception)|go:"GO:0042622"(photoreceptor outer segment membrane)|go:"GO:0046872"(metal ion binding)|go:"GO:0047555"(3',5'-cyclic-GMP phosphodiesterase activity)|go:"GO:0060041"(retina development in camera-type eye)|go:"GO:0097381"(photoreceptor disc membrane)|interpro:IPR002073(3'5'-cyclic nucleotide phosphodiesterase)|interpro:IPR003018(GAF)|interpro:IPR003607(Metal-dependent phosphohydrolase, HD region)|interpro:IPR023174|interpro:IPR029016|interpro:IPR032958|interpro:IPR036971|reactome:R-HSA-2485179|reactome:R-HSA-2514859|reactome:R-HSA-4086398|interpro:IPR023088|refseq:NP_000431.2 - - - comment:"Proteins significantly enriched by immunoprecipitation with 34ED556 (T1) anti-TEX101 antibody in human sperm cells from pre-vasectomy semen samples."|figure legend:Fig. 2B, supplemental Table S6|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-spermatozoa)|taxid:9606(Homo sapiens) - 2020/03/24 2020/04/07 rogid:ZE4tXTFi7lUCcIbCL4KHzY3a6xM9606 rogid:Hxl4f11ifJx6l+UPDb3FqEz3QgI9606 rigid:TX1oljMyfkimcULEvhCJR/BRAW4 false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9BY14 uniprotkb:Q9Y6B6 intact:EBI-12549378|ensembl:ENSP00000472769|uniprotkb:Q7L5R2|uniprotkb:Q9BPY7 intact:EBI-4290665|uniprotkb:D3DQA4|uniprotkb:Q567T4|ensembl:ENSP00000385432|ensembl:ENSP00000404997 psi-mi:tx101_human(display_long)|uniprotkb:TEX101(gene name)|psi-mi:TEX101(display_short)|uniprotkb:Cell surface receptor NYD-SP8(gene name synonym)|uniprotkb:SGRG(gene name synonym)|uniprotkb:Scleroderma-associated autoantigen(gene name synonym)|uniprotkb:Spermatogenesis-related gene protein(gene name synonym)|uniprotkb:UNQ867/PRO1884(orf name) psi-mi:sar1b_human(display_long)|uniprotkb:SAR1B(gene name)|psi-mi:SAR1B(display_short)|uniprotkb:SARA2(gene name synonym)|uniprotkb:SARB(gene name synonym)|uniprotkb:GTP-binding protein B(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Schiza et al. (2018) imex:IM-28077|pubmed:30097533 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-25505396|imex:IM-28077-7 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000131126(gene)|ensembl:ENST00000598265(transcript)|go:"GO:0001669"(acrosomal vesicle)|go:"GO:0002080"(acrosomal membrane)|go:"GO:0005576"(extracellular region)|go:"GO:0005886"(plasma membrane)|go:"GO:0007339"(binding of sperm to zona pellucida)|go:"GO:0009566"(fertilization)|go:"GO:0030317"(flagellated sperm motility)|go:"GO:0044853"(plasma membrane raft)|go:"GO:0046658"(anchored component of plasma membrane)|go:"GO:1901317"(regulation of flagellated sperm motility)|interpro:IPR016054(Ly-6 antigen / uPA receptor -like)|rcsb pdb:7BPR|reactome:R-HSA-163125|refseq:NP_001123483.1|refseq:NP_113639.4 ensembl:ENSG00000152700(gene)|ensembl:ENST00000402673(transcript)|ensembl:ENST00000439578(transcript)|go:"GO:0002474"(antigen processing and presentation of peptide antigen via MHC class I)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005829"(cytosol)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0012507"(ER to Golgi transport vesicle membrane)|go:"GO:0016050"(vesicle organization)|go:"GO:0030127"(COPII vesicle coat)|go:"GO:0032580"(Golgi cisterna membrane)|go:"GO:0046872"(metal ion binding)|go:"GO:0061024"(membrane organization)|go:"GO:0070863"(positive regulation of protein exit from endoplasmic reticulum)|go:"GO:0070971"(endoplasmic reticulum exit site)|interpro:IPR005225(Small GTP-binding protein)|interpro:IPR006687(GTP-binding protein SAR1)|interpro:IPR006689(ARF/SAR superfamily)|go:"GO:0003400"(regulation of COPII vesicle coating)|interpro:IPR027417|reactome:R-HSA-204005|reactome:R-HSA-2132295|reactome:R-HSA-5694530|reactome:R-HSA-8963888|reactome:R-HSA-983170|reactome:R-HSA-1655829|refseq:NP_001028675.1|refseq:NP_057187.1|refseq:XP_016865010.1 - - - comment:"Proteins significantly enriched by immunoprecipitation with 34ED556 (T1) anti-TEX101 antibody in human sperm cells from pre-vasectomy semen samples."|figure legend:Fig. 2B, supplemental Table S6|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-spermatozoa)|taxid:9606(Homo sapiens) - 2020/03/24 2020/04/07 rogid:ZE4tXTFi7lUCcIbCL4KHzY3a6xM9606 rogid:Tq+D9CeccMteZSbthpVFFBuazjY9606 rigid:TX1oljMyfkimcULEvhCJR/BRAW4 false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9BY14 uniprotkb:P10606 intact:EBI-12549378|ensembl:ENSP00000472769|uniprotkb:Q7L5R2|uniprotkb:Q9BPY7 intact:EBI-1053725|uniprotkb:Q96J18|uniprotkb:Q99610|uniprotkb:Q53YB7|ensembl:ENSP00000258424 psi-mi:tx101_human(display_long)|uniprotkb:TEX101(gene name)|psi-mi:TEX101(display_short)|uniprotkb:Cell surface receptor NYD-SP8(gene name synonym)|uniprotkb:SGRG(gene name synonym)|uniprotkb:Scleroderma-associated autoantigen(gene name synonym)|uniprotkb:Spermatogenesis-related gene protein(gene name synonym)|uniprotkb:UNQ867/PRO1884(orf name) psi-mi:cox5b_human(display_long)|uniprotkb:Cytochrome c oxidase polypeptide Vb(gene name synonym)|uniprotkb:COX5B(gene name)|psi-mi:COX5B(display_short) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Schiza et al. (2018) imex:IM-28077|pubmed:30097533 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-25505396|imex:IM-28077-7 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000131126(gene)|ensembl:ENST00000598265(transcript)|go:"GO:0001669"(acrosomal vesicle)|go:"GO:0002080"(acrosomal membrane)|go:"GO:0005576"(extracellular region)|go:"GO:0005886"(plasma membrane)|go:"GO:0007339"(binding of sperm to zona pellucida)|go:"GO:0009566"(fertilization)|go:"GO:0030317"(flagellated sperm motility)|go:"GO:0044853"(plasma membrane raft)|go:"GO:0046658"(anchored component of plasma membrane)|go:"GO:1901317"(regulation of flagellated sperm motility)|interpro:IPR016054(Ly-6 antigen / uPA receptor -like)|rcsb pdb:7BPR|reactome:R-HSA-163125|refseq:NP_001123483.1|refseq:NP_113639.4 refseq:NP_001853.2|ensembl:ENSG00000135940(gene)|ensembl:ENST00000258424(transcript)|go:"GO:0004129"(cytochrome-c oxidase activity)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005751"(mitochondrial respiratory chain complex IV)|go:"GO:0006123"(mitochondrial electron transport, cytochrome c to oxygen)|go:"GO:0007585"(respiratory gaseous exchange by respiratory system)|go:"GO:0046872"(metal ion binding)|interpro:IPR002124(Cytochrome c oxidase, subunit Vb)|interpro:IPR020893|interpro:IPR036972|rcsb pdb:5Z62|reactome:R-HSA-5628897|reactome:R-HSA-611105|reactome:R-HSA-9707564 - - - comment:"Proteins significantly enriched by immunoprecipitation with 34ED556 (T1) anti-TEX101 antibody in human sperm cells from pre-vasectomy semen samples."|figure legend:Fig. 2B, supplemental Table S6|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-spermatozoa)|taxid:9606(Homo sapiens) - 2020/03/24 2020/04/07 rogid:ZE4tXTFi7lUCcIbCL4KHzY3a6xM9606 rogid:EG8kMS2jKMWzQQokTXS2bYk4fHc9606 rigid:TX1oljMyfkimcULEvhCJR/BRAW4 false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9BY14 uniprotkb:P14384 intact:EBI-12549378|ensembl:ENSP00000472769|uniprotkb:Q7L5R2|uniprotkb:Q9BPY7 intact:EBI-2561541|ensembl:ENSP00000339157|ensembl:ENSP00000447255|ensembl:ENSP00000448517|uniprotkb:B2R800|uniprotkb:Q9H2K9 psi-mi:tx101_human(display_long)|uniprotkb:TEX101(gene name)|psi-mi:TEX101(display_short)|uniprotkb:Cell surface receptor NYD-SP8(gene name synonym)|uniprotkb:SGRG(gene name synonym)|uniprotkb:Scleroderma-associated autoantigen(gene name synonym)|uniprotkb:Spermatogenesis-related gene protein(gene name synonym)|uniprotkb:UNQ867/PRO1884(orf name) psi-mi:cbpm_human(display_long)|uniprotkb:CPM(gene name)|psi-mi:CPM(display_short) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Schiza et al. (2018) imex:IM-28077|pubmed:30097533 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-25505396|imex:IM-28077-7 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000131126(gene)|ensembl:ENST00000598265(transcript)|go:"GO:0001669"(acrosomal vesicle)|go:"GO:0002080"(acrosomal membrane)|go:"GO:0005576"(extracellular region)|go:"GO:0005886"(plasma membrane)|go:"GO:0007339"(binding of sperm to zona pellucida)|go:"GO:0009566"(fertilization)|go:"GO:0030317"(flagellated sperm motility)|go:"GO:0044853"(plasma membrane raft)|go:"GO:0046658"(anchored component of plasma membrane)|go:"GO:1901317"(regulation of flagellated sperm motility)|interpro:IPR016054(Ly-6 antigen / uPA receptor -like)|rcsb pdb:7BPR|reactome:R-HSA-163125|refseq:NP_001123483.1|refseq:NP_113639.4 ensembl:ENSG00000135678(gene)|ensembl:ENST00000338356(transcript)|ensembl:ENST00000546373(transcript)|ensembl:ENST00000551568(transcript)|go:"GO:0004180"(carboxypeptidase activity)|refseq:NP_001005502.1|refseq:NP_001865.1|refseq:NP_938079.1|go:"GO:0004181"(metallocarboxypeptidase activity)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0005886"(plasma membrane)|go:"GO:0006518"(peptide metabolic process)|go:"GO:0008270"(zinc ion binding)|go:"GO:0009653"(anatomical structure morphogenesis)|go:"GO:0009986"(cell surface)|go:"GO:0016485"(protein processing)|go:"GO:0031225"(anchored component of membrane)|go:"GO:0070062"(extracellular exosome)|interpro:IPR000834(Peptidase M14, carboxypeptidase A)|interpro:IPR008969(Carboxypeptidase-like, regulatory region)|interpro:IPR033842|rcsb pdb:1UWY|reactome:R-HSA-163125 - - - comment:"Proteins significantly enriched by immunoprecipitation with 34ED556 (T1) anti-TEX101 antibody in human sperm cells from pre-vasectomy semen samples."|figure legend:Fig. 2B, supplemental Table S6|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-spermatozoa)|taxid:9606(Homo sapiens) - 2020/03/24 2020/04/07 rogid:ZE4tXTFi7lUCcIbCL4KHzY3a6xM9606 rogid:nczGYHxDk+MrUSPPoJM1pyDJYFA9606 rigid:TX1oljMyfkimcULEvhCJR/BRAW4 false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9BY14 uniprotkb:P20142 intact:EBI-12549378|ensembl:ENSP00000472769|uniprotkb:Q7L5R2|uniprotkb:Q9BPY7 intact:EBI-25505421|ensembl:ENSP00000362116|uniprotkb:B4DVZ3|uniprotkb:Q5T3D7|uniprotkb:Q5T3D8 psi-mi:tx101_human(display_long)|uniprotkb:TEX101(gene name)|psi-mi:TEX101(display_short)|uniprotkb:Cell surface receptor NYD-SP8(gene name synonym)|uniprotkb:SGRG(gene name synonym)|uniprotkb:Scleroderma-associated autoantigen(gene name synonym)|uniprotkb:Spermatogenesis-related gene protein(gene name synonym)|uniprotkb:UNQ867/PRO1884(orf name) psi-mi:pepc_human(display_long)|uniprotkb:PGC(gene name)|psi-mi:PGC(display_short)|uniprotkb:Pepsinogen C(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Schiza et al. (2018) imex:IM-28077|pubmed:30097533 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-25505396|imex:IM-28077-7 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000131126(gene)|ensembl:ENST00000598265(transcript)|go:"GO:0001669"(acrosomal vesicle)|go:"GO:0002080"(acrosomal membrane)|go:"GO:0005576"(extracellular region)|go:"GO:0005886"(plasma membrane)|go:"GO:0007339"(binding of sperm to zona pellucida)|go:"GO:0009566"(fertilization)|go:"GO:0030317"(flagellated sperm motility)|go:"GO:0044853"(plasma membrane raft)|go:"GO:0046658"(anchored component of plasma membrane)|go:"GO:1901317"(regulation of flagellated sperm motility)|interpro:IPR016054(Ly-6 antigen / uPA receptor -like)|rcsb pdb:7BPR|reactome:R-HSA-163125|refseq:NP_001123483.1|refseq:NP_113639.4 ensembl:ENST00000373025(transcript)|go:"GO:0002803"(positive regulation of antibacterial peptide production)|go:"GO:0004190"(aspartic-type endopeptidase activity)|go:"GO:0005615"(extracellular space)|go:"GO:0006508"(proteolysis)|go:"GO:0007586"(digestion)|interpro:IPR001461(Peptidase A1)|interpro:IPR001969(Peptidase aspartic, active site)|interpro:IPR012848(Propeptide, peptidase A1)|interpro:IPR021109|interpro:IPR033121|interpro:IPR033735|rcsb pdb:1AVF|rcsb pdb:1HTR|ensembl:ENSG00000096088(gene)|refseq:NP_001159896.1|refseq:NP_002621.1 - - - comment:"Proteins significantly enriched by immunoprecipitation with 34ED556 (T1) anti-TEX101 antibody in human sperm cells from pre-vasectomy semen samples."|figure legend:Fig. 2B, supplemental Table S6|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-spermatozoa)|taxid:9606(Homo sapiens) - 2020/03/24 2020/04/07 rogid:ZE4tXTFi7lUCcIbCL4KHzY3a6xM9606 rogid:2eQsQY3Un7S8Be8awfIyzQTmdUI9606 rigid:TX1oljMyfkimcULEvhCJR/BRAW4 false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9BY14 uniprotkb:P10809 intact:EBI-12549378|ensembl:ENSP00000472769|uniprotkb:Q7L5R2|uniprotkb:Q9BPY7 intact:EBI-352528|ensembl:ENSP00000340019|ensembl:ENSP00000373620|ensembl:ENSP00000396460|ensembl:ENSP00000402478|ensembl:ENSP00000412227|ensembl:ENSP00000412717|ensembl:ENSP00000414446|ensembl:ENSP00000503139|ensembl:ENSP00000503894|uniprotkb:Q38L19|uniprotkb:B2R5M6|uniprotkb:Q9UCR6|uniprotkb:B7Z712 psi-mi:tx101_human(display_long)|uniprotkb:TEX101(gene name)|psi-mi:TEX101(display_short)|uniprotkb:Cell surface receptor NYD-SP8(gene name synonym)|uniprotkb:SGRG(gene name synonym)|uniprotkb:Scleroderma-associated autoantigen(gene name synonym)|uniprotkb:Spermatogenesis-related gene protein(gene name synonym)|uniprotkb:UNQ867/PRO1884(orf name) psi-mi:ch60_human(display_long)|uniprotkb:HSPD1(gene name)|psi-mi:HSPD1(display_short)|uniprotkb:HSP60(gene name synonym)|uniprotkb:Heat shock protein 60(gene name synonym)|uniprotkb:60 kDa chaperonin(gene name synonym)|uniprotkb:Chaperonin 60(gene name synonym)|uniprotkb:Mitochondrial matrix protein P1(gene name synonym)|uniprotkb:P60 lymphocyte protein(gene name synonym)|uniprotkb:HuCHA60(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Schiza et al. (2018) imex:IM-28077|pubmed:30097533 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-25505396|imex:IM-28077-7 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000131126(gene)|ensembl:ENST00000598265(transcript)|go:"GO:0001669"(acrosomal vesicle)|go:"GO:0002080"(acrosomal membrane)|go:"GO:0005576"(extracellular region)|go:"GO:0005886"(plasma membrane)|go:"GO:0007339"(binding of sperm to zona pellucida)|go:"GO:0009566"(fertilization)|go:"GO:0030317"(flagellated sperm motility)|go:"GO:0044853"(plasma membrane raft)|go:"GO:0046658"(anchored component of plasma membrane)|go:"GO:1901317"(regulation of flagellated sperm motility)|interpro:IPR016054(Ly-6 antigen / uPA receptor -like)|rcsb pdb:7BPR|reactome:R-HSA-163125|refseq:NP_001123483.1|refseq:NP_113639.4 refseq:NP_002147.2|refseq:NP_955472.1|ensembl:ENSG00000144381(gene)|ensembl:ENST00000345042(transcript)|ensembl:ENST00000388968(transcript)|ensembl:ENST00000418022(transcript)|ensembl:ENST00000426480(transcript)|ensembl:ENST00000428204(transcript)|ensembl:ENST00000439605(transcript)|ensembl:ENST00000452200(transcript)|ensembl:ENST00000677913(transcript)|ensembl:ENST00000678761(transcript)|go:"GO:0001530"(lipopolysaccharide binding)|go:"GO:0001666"(response to hypoxia)|go:"GO:0002039"(p53 binding)|go:"GO:0002755"(MyD88-dependent toll-like receptor signaling pathway)|go:"GO:0002842"(positive regulation of T cell mediated immune response to tumor cell)|go:"GO:0002931"(response to ischemia)|go:"GO:0003688"(DNA replication origin binding)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0003725"(double-stranded RNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0032727"(positive regulation of interferon-alpha production)|go:"GO:0032729"(positive regulation of interferon-gamma production)|go:"GO:0032733"(positive regulation of interleukin-10 production)|go:"GO:0032735"(positive regulation of interleukin-12 production)|go:"GO:0032755"(positive regulation of interleukin-6 production)|go:"GO:0032760"(positive regulation of tumor necrosis factor production)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033198"(response to ATP)|go:"GO:0034185"(apolipoprotein binding)|go:"GO:0034186"(apolipoprotein A-I binding)|go:"GO:0034514"(mitochondrial unfolded protein response)|go:"GO:0034605"(cellular response to heat)|go:"GO:0042026"(protein refolding)|go:"GO:0042100"(B cell proliferation)|go:"GO:0042110"(T cell activation)|go:"GO:0042113"(B cell activation)|go:"GO:0042220"(response to cocaine)|go:"GO:0042493"|go:"GO:0042542"(response to hydrogen peroxide)|go:"GO:0042588"(zymogen granule)|go:"GO:0043032"(positive regulation of macrophage activation)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0005615"(extracellular space)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0005769"(early endosome)|go:"GO:0005782"(peroxisomal matrix)|go:"GO:0005791"(rough endoplasmic reticulum)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005905"(clathrin-coated pit)|go:"GO:0006457"(protein folding)|go:"GO:0006458"('de novo' protein folding)|go:"GO:0006919"(activation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0006986"(response to unfolded protein)|go:"GO:0008035"(high-density lipoprotein particle binding)|go:"GO:0008637"(apoptotic mitochondrial changes)|go:"GO:0009409"(response to cold)|go:"GO:0009986"(cell surface)|go:"GO:0014823"(response to activity)|go:"GO:0016020"(membrane)|go:"GO:0016853"(isomerase activity)|go:"GO:0016887"(ATP hydrolysis activity)|go:"GO:0019899"(enzyme binding)|go:"GO:0030061"(mitochondrial crista)|go:"GO:0030135"(coated vesicle)|go:"GO:0030141"(secretory granule)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0031985"(Golgi cisterna)|go:"GO:0032496"(response to lipopolysaccharide)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0043627"(response to estrogen)|go:"GO:0045041"(protein import into mitochondrial intermembrane space)|go:"GO:0045121"(membrane raft)|go:"GO:0046696"(lipopolysaccharide receptor complex)|go:"GO:0048291"(isotype switching to IgG isotypes)|go:"GO:0050729"(positive regulation of inflammatory response)|go:"GO:0050821"(protein stabilization)|go:"GO:0050870"(positive regulation of T cell activation)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0051087"(chaperone binding)|go:"GO:0051131"(chaperone-mediated protein complex assembly)|go:"GO:0051384"(response to glucocorticoid)|go:"GO:0051604"(protein maturation)|go:"GO:0051702"(biological process involved in interaction with symbiont)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071866"(negative regulation of apoptotic process in bone marrow cell)|go:"GO:0097225"(sperm midpiece)|go:"GO:0098761"(cellular response to interleukin-7)|go:"GO:0140030"(modification-dependent protein binding)|go:"GO:1903427"(negative regulation of reactive oxygen species biosynthetic process)|interpro:IPR001844(Chaperonin Cpn60)|interpro:IPR002423(Chaperonin Cpn60/TCP-1)|interpro:IPR018370|interpro:IPR027409|interpro:IPR027410|interpro:IPR027413|mint:P10809|rcsb pdb:4PJ1|rcsb pdb:6HT7|rcsb pdb:6MRC|rcsb pdb:6MRD|rcsb pdb:7AZP|reactome:R-HSA-1268020|reactome:R-HSA-8869496|dip:DIP-58N - - - comment:"Proteins significantly enriched by immunoprecipitation with 34ED556 (T1) anti-TEX101 antibody in human sperm cells from pre-vasectomy semen samples."|figure legend:Fig. 2B, supplemental Table S6|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-spermatozoa)|taxid:9606(Homo sapiens) - 2020/03/24 2020/04/07 rogid:ZE4tXTFi7lUCcIbCL4KHzY3a6xM9606 rogid:syB2vt66Cpr2mJROfbxoPevoiRE9606 rigid:TX1oljMyfkimcULEvhCJR/BRAW4 false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9BY14 uniprotkb:P22748 intact:EBI-12549378|ensembl:ENSP00000472769|uniprotkb:Q7L5R2|uniprotkb:Q9BPY7 intact:EBI-3906285|uniprotkb:Q6FHI7|ensembl:ENSP00000300900|uniprotkb:B4DQA4 psi-mi:tx101_human(display_long)|uniprotkb:TEX101(gene name)|psi-mi:TEX101(display_short)|uniprotkb:Cell surface receptor NYD-SP8(gene name synonym)|uniprotkb:SGRG(gene name synonym)|uniprotkb:Scleroderma-associated autoantigen(gene name synonym)|uniprotkb:Spermatogenesis-related gene protein(gene name synonym)|uniprotkb:UNQ867/PRO1884(orf name) psi-mi:cah4_human(display_long)|uniprotkb:CA4(gene name)|psi-mi:CA4(display_short)|uniprotkb:Carbonate dehydratase IV(gene name synonym)|uniprotkb:Carbonic anhydrase IV(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Schiza et al. (2018) imex:IM-28077|pubmed:30097533 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-25505396|imex:IM-28077-7 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000131126(gene)|ensembl:ENST00000598265(transcript)|go:"GO:0001669"(acrosomal vesicle)|go:"GO:0002080"(acrosomal membrane)|go:"GO:0005576"(extracellular region)|go:"GO:0005886"(plasma membrane)|go:"GO:0007339"(binding of sperm to zona pellucida)|go:"GO:0009566"(fertilization)|go:"GO:0030317"(flagellated sperm motility)|go:"GO:0044853"(plasma membrane raft)|go:"GO:0046658"(anchored component of plasma membrane)|go:"GO:1901317"(regulation of flagellated sperm motility)|interpro:IPR016054(Ly-6 antigen / uPA receptor -like)|rcsb pdb:7BPR|reactome:R-HSA-163125|refseq:NP_001123483.1|refseq:NP_113639.4 refseq:NP_000708.1|ensembl:ENSG00000167434(gene)|ensembl:ENST00000300900(transcript)|go:"GO:0004089"(carbonate dehydratase activity)|go:"GO:0005791"(rough endoplasmic reticulum)|go:"GO:0005793"(endoplasmic reticulum-Golgi intermediate compartment)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0005886"(plasma membrane)|go:"GO:0006730"(one-carbon metabolic process)|go:"GO:0008270"(zinc ion binding)|go:"GO:0009986"(cell surface)|go:"GO:0015701"(bicarbonate transport)|go:"GO:0016020"(membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0016836"(hydro-lyase activity)|go:"GO:0030658"(transport vesicle membrane)|go:"GO:0030667"(secretory granule membrane)|go:"GO:0031362"(anchored component of external side of plasma membrane)|go:"GO:0031526"(brush border membrane)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0070062"(extracellular exosome)|interpro:IPR001148(Carbonic anhydrase, eukaryotic)|interpro:IPR018338|interpro:IPR018343|interpro:IPR023561|interpro:IPR036398|interpro:IPR041874|rcsb pdb:1ZNC|rcsb pdb:3F7B|rcsb pdb:3F7U|rcsb pdb:3FW3|rcsb pdb:5IPZ|rcsb pdb:5JN8|rcsb pdb:5JN9|rcsb pdb:5JNA|rcsb pdb:5JNC|rcsb pdb:5KU6|reactome:R-HSA-1237044|reactome:R-HSA-1247673|reactome:R-HSA-1475029|refseq:XP_016880501.1 - - - comment:"Proteins significantly enriched by immunoprecipitation with 34ED556 (T1) anti-TEX101 antibody in human sperm cells from pre-vasectomy semen samples."|figure legend:Fig. 2B, supplemental Table S6|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-spermatozoa)|taxid:9606(Homo sapiens) - 2020/03/24 2020/04/07 rogid:ZE4tXTFi7lUCcIbCL4KHzY3a6xM9606 rogid:BIoSJjPGq5xalERuqhZzBpsu7Dk9606 rigid:TX1oljMyfkimcULEvhCJR/BRAW4 false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9BY14 uniprotkb:Q9HAT0 intact:EBI-12549378|ensembl:ENSP00000472769|uniprotkb:Q7L5R2|uniprotkb:Q9BPY7 intact:EBI-1378139|uniprotkb:Q9UF38|uniprotkb:D3DN99|ensembl:ENSP00000184183|ensembl:ENSP00000385919|ensembl:ENSP00000483603 psi-mi:tx101_human(display_long)|uniprotkb:TEX101(gene name)|psi-mi:TEX101(display_short)|uniprotkb:Cell surface receptor NYD-SP8(gene name synonym)|uniprotkb:SGRG(gene name synonym)|uniprotkb:Scleroderma-associated autoantigen(gene name synonym)|uniprotkb:Spermatogenesis-related gene protein(gene name synonym)|uniprotkb:UNQ867/PRO1884(orf name) psi-mi:rop1a_human(display_long)|uniprotkb:ROPN1A(gene name synonym)|uniprotkb:Rhophilin-associated protein 1A(gene name synonym)|uniprotkb:Cancer/testis antigen 91(gene name synonym)|uniprotkb:ROPN1(gene name)|psi-mi:ROPN1(display_short) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Schiza et al. (2018) imex:IM-28077|pubmed:30097533 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-25505396|imex:IM-28077-7 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000131126(gene)|ensembl:ENST00000598265(transcript)|go:"GO:0001669"(acrosomal vesicle)|go:"GO:0002080"(acrosomal membrane)|go:"GO:0005576"(extracellular region)|go:"GO:0005886"(plasma membrane)|go:"GO:0007339"(binding of sperm to zona pellucida)|go:"GO:0009566"(fertilization)|go:"GO:0030317"(flagellated sperm motility)|go:"GO:0044853"(plasma membrane raft)|go:"GO:0046658"(anchored component of plasma membrane)|go:"GO:1901317"(regulation of flagellated sperm motility)|interpro:IPR016054(Ly-6 antigen / uPA receptor -like)|rcsb pdb:7BPR|reactome:R-HSA-163125|refseq:NP_001123483.1|refseq:NP_113639.4 refseq:NP_060048.2|refseq:XP_011511235.1|refseq:XP_011511236.1|refseq:NP_001304703.1|ensembl:ENSG00000065371(gene)|ensembl:ENST00000184183(transcript)|ensembl:ENST00000405845(transcript)|ensembl:ENST00000620893(transcript)|go:"GO:0001932"(regulation of protein phosphorylation)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0030317"(flagellated sperm motility)|go:"GO:0031514"(motile cilium)|go:"GO:0042802"(identical protein binding)|go:"GO:0044782"(cilium organization)|go:"GO:0048240"(sperm capacitation)|go:"GO:0061512"(protein localization to cilium)|reactome:R-HSA-5666185 - - - comment:"Proteins significantly enriched by immunoprecipitation with 34ED556 (T1) anti-TEX101 antibody in human sperm cells from pre-vasectomy semen samples."|figure legend:Fig. 2B, supplemental Table S6|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-spermatozoa)|taxid:9606(Homo sapiens) - 2020/03/24 2020/04/07 rogid:ZE4tXTFi7lUCcIbCL4KHzY3a6xM9606 rogid:OldmtXYRq4LjBZKsJ26yM3iB3sE9606 rigid:TX1oljMyfkimcULEvhCJR/BRAW4 false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9BY14 uniprotkb:P21912 intact:EBI-12549378|ensembl:ENSP00000472769|uniprotkb:Q7L5R2|uniprotkb:Q9BPY7 intact:EBI-1056481|uniprotkb:Q9NQ12|uniprotkb:Q0QEY7|uniprotkb:B2R545|ensembl:ENSP00000364649 psi-mi:tx101_human(display_long)|uniprotkb:TEX101(gene name)|psi-mi:TEX101(display_short)|uniprotkb:Cell surface receptor NYD-SP8(gene name synonym)|uniprotkb:SGRG(gene name synonym)|uniprotkb:Scleroderma-associated autoantigen(gene name synonym)|uniprotkb:Spermatogenesis-related gene protein(gene name synonym)|uniprotkb:UNQ867/PRO1884(orf name) psi-mi:sdhb_human(display_long)|uniprotkb:SDHB(gene name)|psi-mi:SDHB(display_short)|uniprotkb:SDH(gene name synonym)|uniprotkb:SDH1(gene name synonym)|uniprotkb:Iron-sulfur subunit of complex II(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Schiza et al. (2018) imex:IM-28077|pubmed:30097533 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-25505396|imex:IM-28077-7 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000131126(gene)|ensembl:ENST00000598265(transcript)|go:"GO:0001669"(acrosomal vesicle)|go:"GO:0002080"(acrosomal membrane)|go:"GO:0005576"(extracellular region)|go:"GO:0005886"(plasma membrane)|go:"GO:0007339"(binding of sperm to zona pellucida)|go:"GO:0009566"(fertilization)|go:"GO:0030317"(flagellated sperm motility)|go:"GO:0044853"(plasma membrane raft)|go:"GO:0046658"(anchored component of plasma membrane)|go:"GO:1901317"(regulation of flagellated sperm motility)|interpro:IPR016054(Ly-6 antigen / uPA receptor -like)|rcsb pdb:7BPR|reactome:R-HSA-163125|refseq:NP_001123483.1|refseq:NP_113639.4 refseq:NP_002991.2|ensembl:ENSG00000117118(gene)|ensembl:ENST00000375499(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005749"("mitochondrial respiratory chain complex II, succinate dehydrogenase complex (ubiquinone)")|go:"GO:0005886"(plasma membrane)|go:"GO:0006099"(tricarboxylic acid cycle)|go:"GO:0006105"(succinate metabolic process)|go:"GO:0008177"("succinate dehydrogenase (ubiquinone) activity")|go:"GO:0009055"(electron transfer activity)|go:"GO:0009060"(aerobic respiration)|go:"GO:0022904"(respiratory electron transport chain)|go:"GO:0031966"(mitochondrial membrane)|go:"GO:0046872"(metal ion binding)|go:"GO:0048039"(ubiquinone binding)|go:"GO:0051537"(2 iron, 2 sulfur cluster binding)|go:"GO:0051538"(3 iron, 4 sulfur cluster binding)|go:"GO:0051539"(4 iron, 4 sulfur cluster binding)|interpro:IPR001041(Ferredoxin)|interpro:IPR004489(Succinate dehydrogenase/fumarate reductase iron-sulphur protein)|interpro:IPR006058(2Fe-2S ferredoxin, iron-sulphur binding site)|interpro:IPR009051(Alpha-helical ferredoxin)|interpro:IPR012675(Beta-grasp fold, ferredoxin-type)|interpro:IPR017896|interpro:IPR017900|interpro:IPR025192|interpro:IPR036010|reactome:R-HSA-611105|reactome:R-HSA-71403|dip:DIP-39666N - - - comment:"Proteins significantly enriched by immunoprecipitation with 34ED556 (T1) anti-TEX101 antibody in human sperm cells from pre-vasectomy semen samples."|figure legend:Fig. 2B, supplemental Table S6|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-spermatozoa)|taxid:9606(Homo sapiens) - 2020/03/24 2020/04/07 rogid:ZE4tXTFi7lUCcIbCL4KHzY3a6xM9606 rogid:7xnswe3IVEFJiXqGhxF0Az3EmvE9606 rigid:TX1oljMyfkimcULEvhCJR/BRAW4 false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9BY14 uniprotkb:Q9HBV2 intact:EBI-12549378|ensembl:ENSP00000472769|uniprotkb:Q7L5R2|uniprotkb:Q9BPY7 intact:EBI-17498703|ensembl:ENSP00000237201 psi-mi:tx101_human(display_long)|uniprotkb:TEX101(gene name)|psi-mi:TEX101(display_short)|uniprotkb:Cell surface receptor NYD-SP8(gene name synonym)|uniprotkb:SGRG(gene name synonym)|uniprotkb:Scleroderma-associated autoantigen(gene name synonym)|uniprotkb:Spermatogenesis-related gene protein(gene name synonym)|uniprotkb:UNQ867/PRO1884(orf name) psi-mi:saca1_human(display_long)|uniprotkb:Sperm acrosomal membrane-associated protein 32(gene name synonym)|uniprotkb:SPACA1(gene name)|psi-mi:SPACA1(display_short)|uniprotkb:SAMP32(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Schiza et al. (2018) imex:IM-28077|pubmed:30097533 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-25505396|imex:IM-28077-7 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000131126(gene)|ensembl:ENST00000598265(transcript)|go:"GO:0001669"(acrosomal vesicle)|go:"GO:0002080"(acrosomal membrane)|go:"GO:0005576"(extracellular region)|go:"GO:0005886"(plasma membrane)|go:"GO:0007339"(binding of sperm to zona pellucida)|go:"GO:0009566"(fertilization)|go:"GO:0030317"(flagellated sperm motility)|go:"GO:0044853"(plasma membrane raft)|go:"GO:0046658"(anchored component of plasma membrane)|go:"GO:1901317"(regulation of flagellated sperm motility)|interpro:IPR016054(Ly-6 antigen / uPA receptor -like)|rcsb pdb:7BPR|reactome:R-HSA-163125|refseq:NP_001123483.1|refseq:NP_113639.4 refseq:NP_112222.1|ensembl:ENSG00000118434(gene)|ensembl:ENST00000237201(transcript)|go:"GO:0001675"(acrosome assembly)|go:"GO:0002079"(inner acrosomal membrane)|go:"GO:0002080"(acrosomal membrane)|go:"GO:0016021"(integral component of membrane)|interpro:IPR037878|mint:Q9HBV2 - - - comment:"Proteins significantly enriched by immunoprecipitation with 34ED556 (T1) anti-TEX101 antibody in human sperm cells from pre-vasectomy semen samples."|figure legend:Fig. 2B, supplemental Table S6|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-spermatozoa)|taxid:9606(Homo sapiens) - 2020/03/24 2020/04/07 rogid:ZE4tXTFi7lUCcIbCL4KHzY3a6xM9606 rogid:En3NT4ITqXIWX5PuoJxbbDDx5Fw9606 rigid:TX1oljMyfkimcULEvhCJR/BRAW4 false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9BY14 uniprotkb:Q96E40 intact:EBI-12549378|ensembl:ENSP00000472769|uniprotkb:Q7L5R2|uniprotkb:Q9BPY7 intact:EBI-722584|uniprotkb:Q9UGQ0|ensembl:ENSP00000348659|ensembl:ENSP00000361209 psi-mi:tx101_human(display_long)|uniprotkb:TEX101(gene name)|psi-mi:TEX101(display_short)|uniprotkb:Cell surface receptor NYD-SP8(gene name synonym)|uniprotkb:SGRG(gene name synonym)|uniprotkb:Scleroderma-associated autoantigen(gene name synonym)|uniprotkb:Spermatogenesis-related gene protein(gene name synonym)|uniprotkb:UNQ867/PRO1884(orf name) psi-mi:saca9_human(display_long)|uniprotkb:SPACA9(gene name)|psi-mi:SPACA9(display_short)|uniprotkb:C9orf9(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Schiza et al. (2018) imex:IM-28077|pubmed:30097533 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-25505396|imex:IM-28077-7 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000131126(gene)|ensembl:ENST00000598265(transcript)|go:"GO:0001669"(acrosomal vesicle)|go:"GO:0002080"(acrosomal membrane)|go:"GO:0005576"(extracellular region)|go:"GO:0005886"(plasma membrane)|go:"GO:0007339"(binding of sperm to zona pellucida)|go:"GO:0009566"(fertilization)|go:"GO:0030317"(flagellated sperm motility)|go:"GO:0044853"(plasma membrane raft)|go:"GO:0046658"(anchored component of plasma membrane)|go:"GO:1901317"(regulation of flagellated sperm motility)|interpro:IPR016054(Ly-6 antigen / uPA receptor -like)|rcsb pdb:7BPR|reactome:R-HSA-163125|refseq:NP_001123483.1|refseq:NP_113639.4 refseq:NP_061829.3|ensembl:ENSG00000165698(gene)|ensembl:ENST00000356311(transcript)|ensembl:ENST00000372136(transcript)|go:"GO:0001669"(acrosomal vesicle)|go:"GO:0005634"(nucleus)|go:"GO:0005881"(cytoplasmic microtubule)|go:"GO:0036064"(ciliary basal body)|go:"GO:0036126"(sperm flagellum)|go:"GO:0048306"(calcium-dependent protein binding)|go:"GO:0097546"(ciliary base)|interpro:IPR027818|refseq:NP_001303826.1|refseq:NP_001303827.1|refseq:NP_001303829.1 - - - comment:"Proteins significantly enriched by immunoprecipitation with 34ED556 (T1) anti-TEX101 antibody in human sperm cells from pre-vasectomy semen samples."|figure legend:Fig. 2B, supplemental Table S6|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-spermatozoa)|taxid:9606(Homo sapiens) - 2020/03/24 2020/04/07 rogid:ZE4tXTFi7lUCcIbCL4KHzY3a6xM9606 rogid:gFAD0V0xCuufALDBqCTdyofBB/U9606 rigid:TX1oljMyfkimcULEvhCJR/BRAW4 false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9BY14 uniprotkb:P09669 intact:EBI-12549378|ensembl:ENSP00000472769|uniprotkb:Q7L5R2|uniprotkb:Q9BPY7 intact:EBI-715040|uniprotkb:B2R4D7|ensembl:ENSP00000297564|ensembl:ENSP00000428150|ensembl:ENSP00000428702|ensembl:ENSP00000428895|ensembl:ENSP00000428965|ensembl:ENSP00000429410|ensembl:ENSP00000429707|ensembl:ENSP00000429714|ensembl:ENSP00000429755|ensembl:ENSP00000429991 psi-mi:tx101_human(display_long)|uniprotkb:TEX101(gene name)|psi-mi:TEX101(display_short)|uniprotkb:Cell surface receptor NYD-SP8(gene name synonym)|uniprotkb:SGRG(gene name synonym)|uniprotkb:Scleroderma-associated autoantigen(gene name synonym)|uniprotkb:Spermatogenesis-related gene protein(gene name synonym)|uniprotkb:UNQ867/PRO1884(orf name) psi-mi:cox6c_human(display_long)|uniprotkb:COX6C(gene name)|psi-mi:COX6C(display_short)|uniprotkb:Cytochrome c oxidase polypeptide VIc(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Schiza et al. (2018) imex:IM-28077|pubmed:30097533 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-25505396|imex:IM-28077-7 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000131126(gene)|ensembl:ENST00000598265(transcript)|go:"GO:0001669"(acrosomal vesicle)|go:"GO:0002080"(acrosomal membrane)|go:"GO:0005576"(extracellular region)|go:"GO:0005886"(plasma membrane)|go:"GO:0007339"(binding of sperm to zona pellucida)|go:"GO:0009566"(fertilization)|go:"GO:0030317"(flagellated sperm motility)|go:"GO:0044853"(plasma membrane raft)|go:"GO:0046658"(anchored component of plasma membrane)|go:"GO:1901317"(regulation of flagellated sperm motility)|interpro:IPR016054(Ly-6 antigen / uPA receptor -like)|rcsb pdb:7BPR|reactome:R-HSA-163125|refseq:NP_001123483.1|refseq:NP_113639.4 refseq:NP_004365.1|refseq:XP_016868509.1|ensembl:ENSG00000164919(gene)|ensembl:ENST00000297564(transcript)|ensembl:ENST00000517682(transcript)|ensembl:ENST00000518171(transcript)|ensembl:ENST00000520271(transcript)|ensembl:ENST00000520468(transcript)|ensembl:ENST00000520517(transcript)|ensembl:ENST00000522934(transcript)|ensembl:ENST00000522940(transcript)|ensembl:ENST00000523016(transcript)|ensembl:ENST00000524245(transcript)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005751"(mitochondrial respiratory chain complex IV)|go:"GO:0006123"(mitochondrial electron transport, cytochrome c to oxygen)|go:"GO:0016021"(integral component of membrane)|interpro:IPR004204(Cytochrome c oxidase subunit VIc)|interpro:IPR034884|interpro:IPR037169|rcsb pdb:5Z62|reactome:R-HSA-5628897|reactome:R-HSA-611105|reactome:R-HSA-9707564|go:"GO:0006091"(generation of precursor metabolites and energy) - - - comment:"Proteins significantly enriched by immunoprecipitation with 34ED556 (T1) anti-TEX101 antibody in human sperm cells from pre-vasectomy semen samples."|figure legend:Fig. 2B, supplemental Table S6|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-spermatozoa)|taxid:9606(Homo sapiens) - 2020/03/24 2020/04/07 rogid:ZE4tXTFi7lUCcIbCL4KHzY3a6xM9606 rogid:Zha4dqasvkWw3ACebJNflgxCVKo9606 rigid:TX1oljMyfkimcULEvhCJR/BRAW4 false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9BY14 uniprotkb:P21266 intact:EBI-12549378|ensembl:ENSP00000472769|uniprotkb:Q7L5R2|uniprotkb:Q9BPY7 intact:EBI-350350|uniprotkb:O60550|uniprotkb:Q96HA3|ensembl:ENSP00000354357|ensembl:ENSP00000256594 psi-mi:tx101_human(display_long)|uniprotkb:TEX101(gene name)|psi-mi:TEX101(display_short)|uniprotkb:Cell surface receptor NYD-SP8(gene name synonym)|uniprotkb:SGRG(gene name synonym)|uniprotkb:Scleroderma-associated autoantigen(gene name synonym)|uniprotkb:Spermatogenesis-related gene protein(gene name synonym)|uniprotkb:UNQ867/PRO1884(orf name) psi-mi:gstm3_human(display_long)|uniprotkb:GSTM3(gene name)|psi-mi:GSTM3(display_short)|uniprotkb:GST5(gene name synonym)|uniprotkb:GSTM3-3(gene name synonym)|uniprotkb:GST class-mu 3(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Schiza et al. (2018) imex:IM-28077|pubmed:30097533 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-25505396|imex:IM-28077-7 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000131126(gene)|ensembl:ENST00000598265(transcript)|go:"GO:0001669"(acrosomal vesicle)|go:"GO:0002080"(acrosomal membrane)|go:"GO:0005576"(extracellular region)|go:"GO:0005886"(plasma membrane)|go:"GO:0007339"(binding of sperm to zona pellucida)|go:"GO:0009566"(fertilization)|go:"GO:0030317"(flagellated sperm motility)|go:"GO:0044853"(plasma membrane raft)|go:"GO:0046658"(anchored component of plasma membrane)|go:"GO:1901317"(regulation of flagellated sperm motility)|interpro:IPR016054(Ly-6 antigen / uPA receptor -like)|rcsb pdb:7BPR|reactome:R-HSA-163125|refseq:NP_001123483.1|refseq:NP_113639.4 refseq:NP_000840.2|interpro:IPR036282|interpro:IPR040079|rcsb pdb:3GTU|reactome:R-HSA-156590|ensembl:ENST00000256594(transcript)|ensembl:ENST00000361066(transcript)|go:"GO:0004364"(glutathione transferase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006749"(glutathione metabolic process)|ensembl:ENSG00000134202(gene)|go:"GO:0008065"(establishment of blood-nerve barrier)|go:"GO:0018916"(nitrobenzene metabolic process)|go:"GO:0019899"(enzyme binding)|go:"GO:0035686"(sperm fibrous sheath)|go:"GO:0042178"(xenobiotic catabolic process)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043295"(glutathione binding)|go:"GO:0043627"(response to estrogen)|go:"GO:0045171"(intercellular bridge)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070458"(cellular detoxification of nitrogen compound)|interpro:IPR003081(Glutathione S-transferase, Mu class)|interpro:IPR004045(Glutathione S-transferase, N-terminal)|interpro:IPR004046(Glutathione S-transferase, C-terminal)|interpro:IPR010987(Glutathione S-transferase, C-terminal-like)|interpro:IPR036249 - - - comment:"Proteins significantly enriched by immunoprecipitation with 34ED556 (T1) anti-TEX101 antibody in human sperm cells from pre-vasectomy semen samples."|figure legend:Fig. 2B, supplemental Table S6|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-spermatozoa)|taxid:9606(Homo sapiens) - 2020/03/24 2020/04/07 rogid:ZE4tXTFi7lUCcIbCL4KHzY3a6xM9606 rogid:9hGeWmuSdPCn0RGJo4mQ/w9tKzo9606 rigid:TX1oljMyfkimcULEvhCJR/BRAW4 false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9BY14 uniprotkb:P07288 intact:EBI-12549378|ensembl:ENSP00000472769|uniprotkb:Q7L5R2|uniprotkb:Q9BPY7 intact:EBI-1220791|uniprotkb:G3XAE3|uniprotkb:Q15096|uniprotkb:Q16272|uniprotkb:Q86TG8|uniprotkb:C9JXH3|uniprotkb:G3V0H4|uniprotkb:Q8IXI4|ensembl:ENSP00000314151 psi-mi:tx101_human(display_long)|uniprotkb:TEX101(gene name)|psi-mi:TEX101(display_short)|uniprotkb:Cell surface receptor NYD-SP8(gene name synonym)|uniprotkb:SGRG(gene name synonym)|uniprotkb:Scleroderma-associated autoantigen(gene name synonym)|uniprotkb:Spermatogenesis-related gene protein(gene name synonym)|uniprotkb:UNQ867/PRO1884(orf name) psi-mi:klk3_human(display_long)|uniprotkb:KLK3(gene name)|psi-mi:KLK3(display_short)|uniprotkb:APS(gene name synonym)|uniprotkb:Kallikrein-3(gene name synonym)|uniprotkb:Semenogelase(gene name synonym)|uniprotkb:Gamma-seminoprotein(gene name synonym)|uniprotkb:P-30 antigen(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Schiza et al. (2018) imex:IM-28077|pubmed:30097533 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-25505396|imex:IM-28077-7 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000131126(gene)|ensembl:ENST00000598265(transcript)|go:"GO:0001669"(acrosomal vesicle)|go:"GO:0002080"(acrosomal membrane)|go:"GO:0005576"(extracellular region)|go:"GO:0005886"(plasma membrane)|go:"GO:0007339"(binding of sperm to zona pellucida)|go:"GO:0009566"(fertilization)|go:"GO:0030317"(flagellated sperm motility)|go:"GO:0044853"(plasma membrane raft)|go:"GO:0046658"(anchored component of plasma membrane)|go:"GO:1901317"(regulation of flagellated sperm motility)|interpro:IPR016054(Ly-6 antigen / uPA receptor -like)|rcsb pdb:7BPR|reactome:R-HSA-163125|refseq:NP_001123483.1|refseq:NP_113639.4 refseq:NP_001025218.1|refseq:NP_001025219.1|refseq:NP_001639.1|interpro:IPR018114|interpro:IPR033116|interpro:IPR043504|mint:P07288|rcsb pdb:1PFA|rcsb pdb:2PSA|rcsb pdb:2ZCH|rcsb pdb:2ZCK|rcsb pdb:2ZCL|rcsb pdb:3QUM|reactome:R-HSA-381426|reactome:R-HSA-5625886|interpro:IPR009003(Peptidase, trypsin-like serine and cysteine)|ensembl:ENST00000326003(transcript)|go:"GO:0002803"(positive regulation of antibacterial peptide production)|go:"GO:0003073"(regulation of systemic arterial blood pressure)|go:"GO:0004175"(endopeptidase activity)|go:"GO:0004252"(serine-type endopeptidase activity)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0005634"(nucleus)|go:"GO:0006508"(proteolysis)|go:"GO:0008236"(serine-type peptidase activity)|go:"GO:0016525"(negative regulation of angiogenesis)|go:"GO:0016811"("hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides")|go:"GO:0030141"(secretory granule)|go:"GO:0031638"(zymogen activation)|go:"GO:0032991"(protein-containing complex)|go:"GO:0044267"(cellular protein metabolic process)|go:"GO:0070062"(extracellular exosome)|interpro:IPR001254(Peptidase S1 and S6, chymotrypsin/Hap)|interpro:IPR001314(Peptidase S1A, chymotrypsin)|ensembl:ENSG00000142515(gene) - - - comment:"Proteins significantly enriched by immunoprecipitation with 34ED556 (T1) anti-TEX101 antibody in human sperm cells from pre-vasectomy semen samples."|figure legend:Fig. 2B, supplemental Table S6|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-spermatozoa)|taxid:9606(Homo sapiens) - 2020/03/24 2020/04/07 rogid:ZE4tXTFi7lUCcIbCL4KHzY3a6xM9606 rogid:zHGrnUnp/rNQg9HsI7RMalBX/BE9606 rigid:TX1oljMyfkimcULEvhCJR/BRAW4 false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9BY14 uniprotkb:P20674 intact:EBI-12549378|ensembl:ENSP00000472769|uniprotkb:Q7L5R2|uniprotkb:Q9BPY7 intact:EBI-715032|uniprotkb:P30045|intact:EBI-1043629|uniprotkb:Q8TB65|ensembl:ENSP00000317780|ensembl:ENSP00000456386 psi-mi:tx101_human(display_long)|uniprotkb:TEX101(gene name)|psi-mi:TEX101(display_short)|uniprotkb:Cell surface receptor NYD-SP8(gene name synonym)|uniprotkb:SGRG(gene name synonym)|uniprotkb:Scleroderma-associated autoantigen(gene name synonym)|uniprotkb:Spermatogenesis-related gene protein(gene name synonym)|uniprotkb:UNQ867/PRO1884(orf name) psi-mi:cox5a_human(display_long)|uniprotkb:Cytochrome c oxidase polypeptide Va(gene name synonym)|uniprotkb:COX5A(gene name)|psi-mi:COX5A(display_short) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Schiza et al. (2018) imex:IM-28077|pubmed:30097533 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-25505396|imex:IM-28077-7 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000131126(gene)|ensembl:ENST00000598265(transcript)|go:"GO:0001669"(acrosomal vesicle)|go:"GO:0002080"(acrosomal membrane)|go:"GO:0005576"(extracellular region)|go:"GO:0005886"(plasma membrane)|go:"GO:0007339"(binding of sperm to zona pellucida)|go:"GO:0009566"(fertilization)|go:"GO:0030317"(flagellated sperm motility)|go:"GO:0044853"(plasma membrane raft)|go:"GO:0046658"(anchored component of plasma membrane)|go:"GO:1901317"(regulation of flagellated sperm motility)|interpro:IPR016054(Ly-6 antigen / uPA receptor -like)|rcsb pdb:7BPR|reactome:R-HSA-163125|refseq:NP_001123483.1|refseq:NP_113639.4 refseq:NP_004246.2|interpro:IPR003204(Cytochrome c oxidase, subunit Va)|interpro:IPR036545|mint:P20674|rcsb pdb:5Z62|reactome:R-HSA-5628897|reactome:R-HSA-611105|reactome:R-HSA-9707564|go:"GO:0046872"(metal ion binding)|ensembl:ENSG00000178741(gene)|ensembl:ENST00000322347(transcript)|ensembl:ENST00000564811(transcript)|go:"GO:0004129"(cytochrome-c oxidase activity)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005751"(mitochondrial respiratory chain complex IV)|go:"GO:0006123"(mitochondrial electron transport, cytochrome c to oxygen)|go:"GO:0009055"(electron transfer activity) - - - comment:"Proteins significantly enriched by immunoprecipitation with 34ED556 (T1) anti-TEX101 antibody in human sperm cells from pre-vasectomy semen samples."|figure legend:Fig. 2B, supplemental Table S6|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-spermatozoa)|taxid:9606(Homo sapiens) - 2020/03/24 2020/04/07 rogid:ZE4tXTFi7lUCcIbCL4KHzY3a6xM9606 rogid:dWvZKYawyJQwN29Mhkm44DXXqhg9606 rigid:TX1oljMyfkimcULEvhCJR/BRAW4 false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9BY14 uniprotkb:P68371 intact:EBI-12549378|ensembl:ENSP00000472769|uniprotkb:Q7L5R2|uniprotkb:Q9BPY7 intact:EBI-351356|uniprotkb:P05217|uniprotkb:A2BFA2|ensembl:ENSP00000341289 psi-mi:tx101_human(display_long)|uniprotkb:TEX101(gene name)|psi-mi:TEX101(display_short)|uniprotkb:Cell surface receptor NYD-SP8(gene name synonym)|uniprotkb:SGRG(gene name synonym)|uniprotkb:Scleroderma-associated autoantigen(gene name synonym)|uniprotkb:Spermatogenesis-related gene protein(gene name synonym)|uniprotkb:UNQ867/PRO1884(orf name) psi-mi:tbb4b_human(display_long)|uniprotkb:TUBB4B(gene name)|psi-mi:TUBB4B(display_short)|uniprotkb:TUBB2C(gene name synonym)|uniprotkb:Tubulin beta-2 chain(gene name synonym)|uniprotkb:Tubulin beta-2C chain(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Schiza et al. (2018) imex:IM-28077|pubmed:30097533 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-25505396|imex:IM-28077-7 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000131126(gene)|ensembl:ENST00000598265(transcript)|go:"GO:0001669"(acrosomal vesicle)|go:"GO:0002080"(acrosomal membrane)|go:"GO:0005576"(extracellular region)|go:"GO:0005886"(plasma membrane)|go:"GO:0007339"(binding of sperm to zona pellucida)|go:"GO:0009566"(fertilization)|go:"GO:0030317"(flagellated sperm motility)|go:"GO:0044853"(plasma membrane raft)|go:"GO:0046658"(anchored component of plasma membrane)|go:"GO:1901317"(regulation of flagellated sperm motility)|interpro:IPR016054(Ly-6 antigen / uPA receptor -like)|rcsb pdb:7BPR|reactome:R-HSA-163125|refseq:NP_001123483.1|refseq:NP_113639.4 refseq:NP_006079.1|ensembl:ENSG00000188229(gene)|go:"GO:0005525"(GTP binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005874"(microtubule)|go:"GO:0035578"(azurophil granule lumen)|go:"GO:0042267"(natural killer cell mediated cytotoxicity)|go:"GO:0042288"(MHC class I protein binding)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0070062"(extracellular exosome)|go:"GO:1903561"(extracellular vesicle)|interpro:IPR000217(Tubulin)|interpro:IPR002453(Beta tubulin)|interpro:IPR003008(Tubulin/FtsZ, GTPase)|interpro:IPR008280(Tubulin/FtsZ, C-terminal)|interpro:IPR013838(Beta tubulin, autoregulation binding site)|go:"GO:0005200"(structural constituent of cytoskeleton)|interpro:IPR017975|interpro:IPR018316|interpro:IPR023123|interpro:IPR036525|interpro:IPR037103|mint:P68371|reactome:R-HSA-1445148|reactome:R-HSA-190840|reactome:R-HSA-190861|reactome:R-HSA-2132295|reactome:R-HSA-2467813|reactome:R-HSA-2500257|reactome:R-HSA-2565942|reactome:R-HSA-3371497|reactome:R-HSA-380259|reactome:R-HSA-380270|reactome:R-HSA-380284|reactome:R-HSA-380320|reactome:R-HSA-389957|reactome:R-HSA-389960|reactome:R-HSA-389977|reactome:R-HSA-437239|reactome:R-HSA-5610787|reactome:R-HSA-5617833|reactome:R-HSA-5620912|reactome:R-HSA-5620924|reactome:R-HSA-5626467|reactome:R-HSA-5663220|reactome:R-HSA-6798695|reactome:R-HSA-6807878|reactome:R-HSA-6811434|reactome:R-HSA-6811436|reactome:R-HSA-68877|reactome:R-HSA-8852276|reactome:R-HSA-8854518|reactome:R-HSA-8955332|reactome:R-HSA-9609690|reactome:R-HSA-9609736|reactome:R-HSA-9619483|reactome:R-HSA-9646399|reactome:R-HSA-9648025|reactome:R-HSA-9668328|reactome:R-HSA-983189|ensembl:ENST00000340384(transcript)|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0003725"(double-stranded RNA binding) - - - comment:"Proteins significantly enriched by immunoprecipitation with 34ED556 (T1) anti-TEX101 antibody in human sperm cells from pre-vasectomy semen samples."|figure legend:Fig. 2B, supplemental Table S6|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-spermatozoa)|taxid:9606(Homo sapiens) - 2020/03/24 2020/04/07 rogid:ZE4tXTFi7lUCcIbCL4KHzY3a6xM9606 rogid:4LwMs7E7eILMjB9Z/1bstAp22CY9606 rigid:TX1oljMyfkimcULEvhCJR/BRAW4 false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9BY14 uniprotkb:Q08431 intact:EBI-12549378|ensembl:ENSP00000472769|uniprotkb:Q7L5R2|uniprotkb:Q9BPY7 intact:EBI-3449497|uniprotkb:Q53FU9|uniprotkb:Q9BTL9|uniprotkb:B2R6M7|uniprotkb:Q7Z3D2|uniprotkb:F5GZN3|ensembl:ENSP00000268150|ensembl:ENSP00000456281 psi-mi:tx101_human(display_long)|uniprotkb:TEX101(gene name)|psi-mi:TEX101(display_short)|uniprotkb:Cell surface receptor NYD-SP8(gene name synonym)|uniprotkb:SGRG(gene name synonym)|uniprotkb:Scleroderma-associated autoantigen(gene name synonym)|uniprotkb:Spermatogenesis-related gene protein(gene name synonym)|uniprotkb:UNQ867/PRO1884(orf name) psi-mi:mfgm_human(display_long)|uniprotkb:MFGE8(gene name)|psi-mi:MFGE8(display_short)|uniprotkb:Breast epithelial antigen BA46(gene name synonym)|uniprotkb:HMFG(gene name synonym)|uniprotkb:MFGM(gene name synonym)|uniprotkb:Milk fat globule-EGF factor 8(gene name synonym)|uniprotkb:SED1(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Schiza et al. (2018) imex:IM-28077|pubmed:30097533 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-25505396|imex:IM-28077-7 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000131126(gene)|ensembl:ENST00000598265(transcript)|go:"GO:0001669"(acrosomal vesicle)|go:"GO:0002080"(acrosomal membrane)|go:"GO:0005576"(extracellular region)|go:"GO:0005886"(plasma membrane)|go:"GO:0007339"(binding of sperm to zona pellucida)|go:"GO:0009566"(fertilization)|go:"GO:0030317"(flagellated sperm motility)|go:"GO:0044853"(plasma membrane raft)|go:"GO:0046658"(anchored component of plasma membrane)|go:"GO:1901317"(regulation of flagellated sperm motility)|interpro:IPR016054(Ly-6 antigen / uPA receptor -like)|rcsb pdb:7BPR|reactome:R-HSA-163125|refseq:NP_001123483.1|refseq:NP_113639.4 refseq:NP_005919.2|refseq:NP_001108086.1|refseq:NP_001297248.1|refseq:NP_001297249.1|refseq:NP_001297250.1|ensembl:ENSG00000140545(gene)|ensembl:ENST00000268150(transcript)|ensembl:ENST00000566497(transcript)|go:"GO:0001525"(angiogenesis)|go:"GO:0001786"(phosphatidylserine binding)|go:"GO:0002080"(acrosomal membrane)|go:"GO:0005178"(integrin binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0005788"(endoplasmic reticulum lumen)|go:"GO:0006910"(phagocytosis, recognition)|go:"GO:0006911"(phagocytosis, engulfment)|go:"GO:0007155"(cell adhesion)|go:"GO:0007338"(single fertilization)|go:"GO:0008429"(phosphatidylethanolamine binding)|go:"GO:0009897"(external side of plasma membrane)|go:"GO:0016020"(membrane)|go:"GO:0019897"(extrinsic component of plasma membrane)|go:"GO:0043277"(apoptotic cell clearance)|go:"GO:0050766"(positive regulation of phagocytosis)|go:"GO:0062023"(collagen-containing extracellular matrix)|go:"GO:0070062"(extracellular exosome)|go:"GO:1903561"(extracellular vesicle)|interpro:IPR000421(Coagulation factor 5/8 type, C-terminal)|interpro:IPR000742(EGF-like, type 3)|interpro:IPR008979(Galactose-binding like)|reactome:R-HSA-381426|reactome:R-HSA-8957275|reactome:R-HSA-977225 - - - comment:"Proteins significantly enriched by immunoprecipitation with 34ED556 (T1) anti-TEX101 antibody in human sperm cells from pre-vasectomy semen samples."|figure legend:Fig. 2B, supplemental Table S6|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-spermatozoa)|taxid:9606(Homo sapiens) - 2020/03/24 2020/04/07 rogid:ZE4tXTFi7lUCcIbCL4KHzY3a6xM9606 rogid:rj2XTJMMYB6NPDRjQX9LSEuF3Qw9606 rigid:TX1oljMyfkimcULEvhCJR/BRAW4 false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9BY14 uniprotkb:Q9BS86 intact:EBI-12549378|ensembl:ENSP00000472769|uniprotkb:Q7L5R2|uniprotkb:Q9BPY7 intact:EBI-3907170|ensembl:ENSP00000046087|uniprotkb:Q15941|uniprotkb:Q75KX9|uniprotkb:Q75MI3|uniprotkb:A4D253|uniprotkb:C9JPU1 psi-mi:tx101_human(display_long)|uniprotkb:TEX101(gene name)|psi-mi:TEX101(display_short)|uniprotkb:Cell surface receptor NYD-SP8(gene name synonym)|uniprotkb:SGRG(gene name synonym)|uniprotkb:Scleroderma-associated autoantigen(gene name synonym)|uniprotkb:Spermatogenesis-related gene protein(gene name synonym)|uniprotkb:UNQ867/PRO1884(orf name) psi-mi:zpbp1_human(display_long)|uniprotkb:ZPBP(gene name)|psi-mi:ZPBP(display_short)|uniprotkb:ZPBP1(gene name synonym)|uniprotkb:Sp38(gene name synonym)|uniprotkb:Inner acrosomal membrane IAM38(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Schiza et al. (2018) imex:IM-28077|pubmed:30097533 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-25505396|imex:IM-28077-7 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000131126(gene)|ensembl:ENST00000598265(transcript)|go:"GO:0001669"(acrosomal vesicle)|go:"GO:0002080"(acrosomal membrane)|go:"GO:0005576"(extracellular region)|go:"GO:0005886"(plasma membrane)|go:"GO:0007339"(binding of sperm to zona pellucida)|go:"GO:0009566"(fertilization)|go:"GO:0030317"(flagellated sperm motility)|go:"GO:0044853"(plasma membrane raft)|go:"GO:0046658"(anchored component of plasma membrane)|go:"GO:1901317"(regulation of flagellated sperm motility)|interpro:IPR016054(Ly-6 antigen / uPA receptor -like)|rcsb pdb:7BPR|reactome:R-HSA-163125|refseq:NP_001123483.1|refseq:NP_113639.4 ensembl:ENSG00000042813(gene)|ensembl:ENST00000046087(transcript)|go:"GO:0001669"(acrosomal vesicle)|go:"GO:0001675"(acrosome assembly)|go:"GO:0002080"(acrosomal membrane)|go:"GO:0002199"(zona pellucida receptor complex)|go:"GO:0005576"(extracellular region)|go:"GO:0005634"(nucleus)|go:"GO:0007339"(binding of sperm to zona pellucida)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR010857(Zona-pellucida-binding)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR036179|refseq:NP_008940.2|refseq:NP_001153350.1 - - - comment:"Proteins significantly enriched by immunoprecipitation with 34ED556 (T1) anti-TEX101 antibody in human sperm cells from pre-vasectomy semen samples."|figure legend:Fig. 2B, supplemental Table S6|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-spermatozoa)|taxid:9606(Homo sapiens) - 2020/03/24 2020/04/07 rogid:ZE4tXTFi7lUCcIbCL4KHzY3a6xM9606 rogid:BI1cOxFgdoQaVsQl3nSAKsObu749606 rigid:TX1oljMyfkimcULEvhCJR/BRAW4 false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9BY14 uniprotkb:A6NGU5 intact:EBI-12549378|ensembl:ENSP00000472769|uniprotkb:Q7L5R2|uniprotkb:Q9BPY7 intact:EBI-21558075 psi-mi:tx101_human(display_long)|uniprotkb:TEX101(gene name)|psi-mi:TEX101(display_short)|uniprotkb:Cell surface receptor NYD-SP8(gene name synonym)|uniprotkb:SGRG(gene name synonym)|uniprotkb:Scleroderma-associated autoantigen(gene name synonym)|uniprotkb:Spermatogenesis-related gene protein(gene name synonym)|uniprotkb:UNQ867/PRO1884(orf name) psi-mi:ggt3_human(display_long)|uniprotkb:Gamma-glutamyltransferase 3(gene name synonym)|uniprotkb:Putative gamma-glutamyltranspeptidase 3(gene name synonym)|uniprotkb:GGT3P(gene name)|psi-mi:GGT3P(display_short)|uniprotkb:GGT3(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Schiza et al. (2018) imex:IM-28077|pubmed:30097533 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-25505396|imex:IM-28077-7 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000131126(gene)|ensembl:ENST00000598265(transcript)|go:"GO:0001669"(acrosomal vesicle)|go:"GO:0002080"(acrosomal membrane)|go:"GO:0005576"(extracellular region)|go:"GO:0005886"(plasma membrane)|go:"GO:0007339"(binding of sperm to zona pellucida)|go:"GO:0009566"(fertilization)|go:"GO:0030317"(flagellated sperm motility)|go:"GO:0044853"(plasma membrane raft)|go:"GO:0046658"(anchored component of plasma membrane)|go:"GO:1901317"(regulation of flagellated sperm motility)|interpro:IPR016054(Ly-6 antigen / uPA receptor -like)|rcsb pdb:7BPR|reactome:R-HSA-163125|refseq:NP_001123483.1|refseq:NP_113639.4 go:"GO:0000048"(peptidyltransferase activity)|go:"GO:0002682"(regulation of immune system process)|go:"GO:0005886"(plasma membrane)|go:"GO:0006750"(glutathione biosynthetic process)|go:"GO:0006751"(glutathione catabolic process)|go:"GO:0007283"(spermatogenesis)|go:"GO:0016021"(integral component of membrane)|go:"GO:0031179"(peptide modification)|go:"GO:0032355"(response to estradiol)|go:"GO:0032496"(response to lipopolysaccharide)|go:"GO:0034612"(response to tumor necrosis factor)|go:"GO:0036374"(glutathione hydrolase activity)|go:"GO:0050727"(regulation of inflammatory response)|go:"GO:0070062"(extracellular exosome)|go:"GO:0102953"(hypoglycin A gamma-glutamyl transpeptidase activity)|go:"GO:0103068"(leukotriene C4 gamma-glutamyl transferase activity)|go:"GO:1901750"(leukotriene D4 biosynthetic process)|reactome:R-HSA-174403|reactome:R-HSA-5423646|interpro:IPR000101(Gamma-glutamyltranspeptidase)|interpro:IPR029055|interpro:IPR043137|interpro:IPR043138 - - - comment:"Proteins significantly enriched by immunoprecipitation with 34ED556 (T1) anti-TEX101 antibody in human sperm cells from pre-vasectomy semen samples."|figure legend:Fig. 2B, supplemental Table S6|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-spermatozoa)|taxid:9606(Homo sapiens) - 2020/03/24 2020/04/07 rogid:ZE4tXTFi7lUCcIbCL4KHzY3a6xM9606 rogid:yzmAA7jbxggQzzaAN4vebSJlFnE9606 rigid:TX1oljMyfkimcULEvhCJR/BRAW4 false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9BY14 uniprotkb:Q1ZYL8 intact:EBI-12549378|ensembl:ENSP00000472769|uniprotkb:Q7L5R2|uniprotkb:Q9BPY7 intact:EBI-25505399|ensembl:ENSP00000378712|uniprotkb:A7RA93|uniprotkb:A7RA94|uniprotkb:Q6UXA2|uniprotkb:Q96FT6|uniprotkb:Q96L02 psi-mi:tx101_human(display_long)|uniprotkb:TEX101(gene name)|psi-mi:TEX101(display_short)|uniprotkb:Cell surface receptor NYD-SP8(gene name synonym)|uniprotkb:SGRG(gene name synonym)|uniprotkb:Scleroderma-associated autoantigen(gene name synonym)|uniprotkb:Spermatogenesis-related gene protein(gene name synonym)|uniprotkb:UNQ867/PRO1884(orf name) psi-mi:izum4_human(display_long)|uniprotkb:IZUMO4(gene name)|psi-mi:IZUMO4(display_short)|uniprotkb:C19orf36(gene name synonym)|uniprotkb:Sperm 22 kDa protein c113(gene name synonym)|uniprotkb:UNQ831/PRO1758(orf name) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Schiza et al. (2018) imex:IM-28077|pubmed:30097533 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-25505396|imex:IM-28077-7 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000131126(gene)|ensembl:ENST00000598265(transcript)|go:"GO:0001669"(acrosomal vesicle)|go:"GO:0002080"(acrosomal membrane)|go:"GO:0005576"(extracellular region)|go:"GO:0005886"(plasma membrane)|go:"GO:0007339"(binding of sperm to zona pellucida)|go:"GO:0009566"(fertilization)|go:"GO:0030317"(flagellated sperm motility)|go:"GO:0044853"(plasma membrane raft)|go:"GO:0046658"(anchored component of plasma membrane)|go:"GO:1901317"(regulation of flagellated sperm motility)|interpro:IPR016054(Ly-6 antigen / uPA receptor -like)|rcsb pdb:7BPR|reactome:R-HSA-163125|refseq:NP_001123483.1|refseq:NP_113639.4 ensembl:ENSG00000099840(gene)|ensembl:ENST00000395301(transcript)|go:"GO:0005576"(extracellular region)|go:"GO:0005634"(nucleus)|interpro:IPR029389|reactome:R-HSA-1300645|refseq:NP_001026905.2|refseq:NP_001034935.1 - - - comment:"Proteins significantly enriched by immunoprecipitation with 34ED556 (T1) anti-TEX101 antibody in human sperm cells from pre-vasectomy semen samples."|figure legend:Fig. 2B, supplemental Table S6|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-spermatozoa)|taxid:9606(Homo sapiens) - 2020/03/24 2020/04/07 rogid:ZE4tXTFi7lUCcIbCL4KHzY3a6xM9606 rogid:sPSzW9IUx4Bj4HlW5Lc514VRZKQ9606 rigid:TX1oljMyfkimcULEvhCJR/BRAW4 false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9BY14 uniprotkb:Q8NBX0 intact:EBI-12549378|ensembl:ENSP00000472769|uniprotkb:Q7L5R2|uniprotkb:Q9BPY7 intact:EBI-4289902|uniprotkb:Q9Y363|uniprotkb:Q8TAR0|ensembl:ENSP00000355467 psi-mi:tx101_human(display_long)|uniprotkb:TEX101(gene name)|psi-mi:TEX101(display_short)|uniprotkb:Cell surface receptor NYD-SP8(gene name synonym)|uniprotkb:SGRG(gene name synonym)|uniprotkb:Scleroderma-associated autoantigen(gene name synonym)|uniprotkb:Spermatogenesis-related gene protein(gene name synonym)|uniprotkb:UNQ867/PRO1884(orf name) psi-mi:scpdl_human(display_long)|uniprotkb:SCCPDH(gene name)|psi-mi:SCCPDH(display_short)|uniprotkb:CGI-49(orf name) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Schiza et al. (2018) imex:IM-28077|pubmed:30097533 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-25505396|imex:IM-28077-7 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000131126(gene)|ensembl:ENST00000598265(transcript)|go:"GO:0001669"(acrosomal vesicle)|go:"GO:0002080"(acrosomal membrane)|go:"GO:0005576"(extracellular region)|go:"GO:0005886"(plasma membrane)|go:"GO:0007339"(binding of sperm to zona pellucida)|go:"GO:0009566"(fertilization)|go:"GO:0030317"(flagellated sperm motility)|go:"GO:0044853"(plasma membrane raft)|go:"GO:0046658"(anchored component of plasma membrane)|go:"GO:1901317"(regulation of flagellated sperm motility)|interpro:IPR016054(Ly-6 antigen / uPA receptor -like)|rcsb pdb:7BPR|reactome:R-HSA-163125|refseq:NP_001123483.1|refseq:NP_113639.4 ensembl:ENSG00000143653(gene)|ensembl:ENST00000366510(transcript)|go:"GO:0005576"(extracellular region)|go:"GO:0005634"(nucleus)|go:"GO:0005739"(mitochondrion)|go:"GO:0005811"(lipid droplet)|go:"GO:0005886"(plasma membrane)|go:"GO:0009247"(glycolipid biosynthetic process)|go:"GO:0016020"(membrane)|go:"GO:0016491"(oxidoreductase activity)|go:"GO:0030496"(midbody)|go:"GO:0031093"(platelet alpha granule lumen)|interpro:IPR005097(Saccharopine dehydrogenase)|interpro:IPR032095|interpro:IPR036291|reactome:R-HSA-114608|refseq:NP_057086.2 - - - comment:"Proteins significantly enriched by immunoprecipitation with 34ED556 (T1) anti-TEX101 antibody in human sperm cells from pre-vasectomy semen samples."|figure legend:Fig. 2B, supplemental Table S6|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-spermatozoa)|taxid:9606(Homo sapiens) - 2020/03/24 2020/04/07 rogid:ZE4tXTFi7lUCcIbCL4KHzY3a6xM9606 rogid:3dd8OvU7odCDI/f4Ouk7CJYoxnI9606 rigid:TX1oljMyfkimcULEvhCJR/BRAW4 false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9BY14 uniprotkb:P50990 intact:EBI-12549378|ensembl:ENSP00000472769|uniprotkb:Q7L5R2|uniprotkb:Q9BPY7 intact:EBI-356507|uniprotkb:A6NN54|uniprotkb:Q4VBP8|uniprotkb:B4DEM7|uniprotkb:B4DQH4|ensembl:ENSP00000286788 psi-mi:tx101_human(display_long)|uniprotkb:TEX101(gene name)|psi-mi:TEX101(display_short)|uniprotkb:Cell surface receptor NYD-SP8(gene name synonym)|uniprotkb:SGRG(gene name synonym)|uniprotkb:Scleroderma-associated autoantigen(gene name synonym)|uniprotkb:Spermatogenesis-related gene protein(gene name synonym)|uniprotkb:UNQ867/PRO1884(orf name) psi-mi:tcpq_human(display_long)|uniprotkb:CCT8(gene name)|psi-mi:CCT8(display_short)|uniprotkb:CCTQ(gene name synonym)|uniprotkb:KIAA0002(gene name synonym)|uniprotkb:CCT-theta(gene name synonym)|uniprotkb:Renal carcinoma antigen NY-REN-15(gene name synonym)|uniprotkb:C21orf112(gene name synonym)|uniprotkb:Chaperonin containing T-complex polypeptide 1 subunit 8(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Schiza et al. (2018) imex:IM-28077|pubmed:30097533 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-25505396|imex:IM-28077-7 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000131126(gene)|ensembl:ENST00000598265(transcript)|go:"GO:0001669"(acrosomal vesicle)|go:"GO:0002080"(acrosomal membrane)|go:"GO:0005576"(extracellular region)|go:"GO:0005886"(plasma membrane)|go:"GO:0007339"(binding of sperm to zona pellucida)|go:"GO:0009566"(fertilization)|go:"GO:0030317"(flagellated sperm motility)|go:"GO:0044853"(plasma membrane raft)|go:"GO:0046658"(anchored component of plasma membrane)|go:"GO:1901317"(regulation of flagellated sperm motility)|interpro:IPR016054(Ly-6 antigen / uPA receptor -like)|rcsb pdb:7BPR|reactome:R-HSA-163125|refseq:NP_001123483.1|refseq:NP_113639.4 refseq:NP_001269836.1|refseq:NP_001269838.1|refseq:NP_006576.2|go:"GO:0034774"(secretory granule lumen)|go:"GO:0035578"(azurophil granule lumen)|go:"GO:0044183"(protein folding chaperone)|go:"GO:0044297"(cell body)|go:"GO:0045111"(intermediate filament cytoskeleton)|go:"GO:0045296"(cadherin binding)|go:"GO:0046931"(pore complex assembly)|go:"GO:0050821"(protein stabilization)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0070062"(extracellular exosome)|go:"GO:1901998"(toxin transport)|go:"GO:1904813"(ficolin-1-rich granule lumen)|go:"GO:1904851"(positive regulation of establishment of protein localization to telomere)|go:"GO:1904871"(positive regulation of protein localization to Cajal body)|go:"GO:1904874"(positive regulation of telomerase RNA localization to Cajal body)|interpro:IPR002194(Chaperonin TCP-1, conserved site)|interpro:IPR002423(Chaperonin Cpn60/TCP-1)|interpro:IPR012721(T-complex protein 1, theta subunit)|interpro:IPR017998|interpro:IPR027409|interpro:IPR027410|interpro:IPR027413|mint:P50990|rcsb pdb:6NR8|rcsb pdb:6NR9|rcsb pdb:6NRA|rcsb pdb:6NRB|rcsb pdb:6NRC|rcsb pdb:6NRD|rcsb pdb:6QB8|rcsb pdb:7LUM|rcsb pdb:7LUP|go:"GO:0032212"(positive regulation of telomere maintenance via telomerase)|reactome:R-HSA-389957|reactome:R-HSA-389960|reactome:R-HSA-390450|reactome:R-HSA-390471|ensembl:ENSG00000156261(gene)|ensembl:ENST00000286788(transcript)|go:"GO:0002199"(zona pellucida receptor complex)|go:"GO:0005524"(ATP binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005832"(chaperonin-containing T-complex)|go:"GO:0005874"(microtubule)|go:"GO:0005929"(cilium)|go:"GO:0006457"(protein folding)|go:"GO:0007339"(binding of sperm to zona pellucida)|go:"GO:0016887"(ATP hydrolysis activity)|reactome:R-HSA-6798695|reactome:R-HSA-6814122|reactome:R-HSA-5620922|dip:DIP-38124N - - - comment:"Proteins significantly enriched by immunoprecipitation with 34ED556 (T1) anti-TEX101 antibody in human sperm cells from pre-vasectomy semen samples."|figure legend:Fig. 2B, supplemental Table S6|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-spermatozoa)|taxid:9606(Homo sapiens) - 2020/03/24 2020/04/07 rogid:ZE4tXTFi7lUCcIbCL4KHzY3a6xM9606 rogid:/TlB7Gk2Z9GPvfV3JBE0nWUF34Y9606 rigid:TX1oljMyfkimcULEvhCJR/BRAW4 false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9BY14 uniprotkb:P11279 intact:EBI-12549378|ensembl:ENSP00000472769|uniprotkb:Q7L5R2|uniprotkb:Q9BPY7 intact:EBI-2805407|uniprotkb:B4DWL3|ensembl:ENSP00000333298|uniprotkb:Q9NP13|uniprotkb:Q8WU33|uniprotkb:Q9BRD2|uniprotkb:Q96I40 psi-mi:tx101_human(display_long)|uniprotkb:TEX101(gene name)|psi-mi:TEX101(display_short)|uniprotkb:Cell surface receptor NYD-SP8(gene name synonym)|uniprotkb:SGRG(gene name synonym)|uniprotkb:Scleroderma-associated autoantigen(gene name synonym)|uniprotkb:Spermatogenesis-related gene protein(gene name synonym)|uniprotkb:UNQ867/PRO1884(orf name) psi-mi:lamp1_human(display_long)|uniprotkb:CD107 antigen-like family member A(gene name synonym)|uniprotkb:LAMP1(gene name)|psi-mi:LAMP1(display_short) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Schiza et al. (2018) imex:IM-28077|pubmed:30097533 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-25505396|imex:IM-28077-7 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000131126(gene)|ensembl:ENST00000598265(transcript)|go:"GO:0001669"(acrosomal vesicle)|go:"GO:0002080"(acrosomal membrane)|go:"GO:0005576"(extracellular region)|go:"GO:0005886"(plasma membrane)|go:"GO:0007339"(binding of sperm to zona pellucida)|go:"GO:0009566"(fertilization)|go:"GO:0030317"(flagellated sperm motility)|go:"GO:0044853"(plasma membrane raft)|go:"GO:0046658"(anchored component of plasma membrane)|go:"GO:1901317"(regulation of flagellated sperm motility)|interpro:IPR016054(Ly-6 antigen / uPA receptor -like)|rcsb pdb:7BPR|reactome:R-HSA-163125|refseq:NP_001123483.1|refseq:NP_113639.4 ensembl:ENSG00000185896(gene)|go:"GO:0016020"(membrane)|go:"GO:0019899"(enzyme binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030285"(integral component of synaptic vesicle membrane)|go:"GO:0030425"(dendrite)|go:"GO:0031902"(late endosome membrane)|go:"GO:0035577"(azurophil granule membrane)|go:"GO:0042383"(sarcolemma)|go:"GO:0042470"(melanosome)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043323"(positive regulation of natural killer cell degranulation)|go:"GO:0044754"(autolysosome)|go:"GO:0045954"(positive regulation of natural killer cell mediated cytotoxicity)|go:"GO:0048102"(autophagic cell death)|go:"GO:0048471"(perinuclear region of cytoplasm)|ensembl:ENST00000332556(transcript)|go:"GO:0000421"(autophagosome membrane)|go:"GO:0001618"(virus receptor activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005764"(lysosome)|go:"GO:0050821"(protein stabilization)|go:"GO:0061474"(phagolysosome membrane)|go:"GO:0070062"(extracellular exosome)|go:"GO:0072594"(establishment of protein localization to organelle)|go:"GO:0090160"(Golgi to lysosome transport)|go:"GO:0097208"(alveolar lamellar body)|go:"GO:0101003"(ficolin-1-rich granule membrane)|go:"GO:0101004"(cytolytic granule membrane)|go:"GO:0140507"(granzyme-mediated programmed cell death signaling pathway)|go:"GO:1902513"(regulation of organelle transport along microtubule)|interpro:IPR002000("Lysosome-associated membrane glycoprotein (Lamp)/CD68")|interpro:IPR018134|mint:P11279|reactome:R-HSA-6798695|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005770"(late endosome)|go:"GO:0005771"(multivesicular body)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0009897"(external side of plasma membrane)|go:"GO:0010008"(endosome membrane)|refseq:NP_005552.3|dip:DIP-44670N - - - comment:"Proteins significantly enriched by immunoprecipitation with 34ED556 (T1) anti-TEX101 antibody in human sperm cells from pre-vasectomy semen samples."|figure legend:Fig. 2B, supplemental Table S6|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-spermatozoa)|taxid:9606(Homo sapiens) - 2020/03/24 2020/04/07 rogid:ZE4tXTFi7lUCcIbCL4KHzY3a6xM9606 rogid:dP5MZG0I7/SM0EfCUhsESfQYvYU9606 rigid:TX1oljMyfkimcULEvhCJR/BRAW4 false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9BY14 uniprotkb:P13987 intact:EBI-12549378|ensembl:ENSP00000472769|uniprotkb:Q7L5R2|uniprotkb:Q9BPY7 intact:EBI-297972|ensembl:ENSP00000340210|ensembl:ENSP00000379191|ensembl:ENSP00000403511|ensembl:ENSP00000404822|ensembl:ENSP00000410182|ensembl:ENSP00000432942|ensembl:ENSP00000494884|ensembl:ENSP00000498448|ensembl:ENSP00000498879|uniprotkb:E9PR17 psi-mi:tx101_human(display_long)|uniprotkb:TEX101(gene name)|psi-mi:TEX101(display_short)|uniprotkb:Cell surface receptor NYD-SP8(gene name synonym)|uniprotkb:SGRG(gene name synonym)|uniprotkb:Scleroderma-associated autoantigen(gene name synonym)|uniprotkb:Spermatogenesis-related gene protein(gene name synonym)|uniprotkb:UNQ867/PRO1884(orf name) psi-mi:cd59_human(display_long)|uniprotkb:CD59(gene name)|psi-mi:CD59(display_short)|uniprotkb:Membrane attack complex inhibition factor(gene name synonym)|uniprotkb:MAC-inhibitory protein(gene name synonym)|uniprotkb:Protectin(gene name synonym)|uniprotkb:MEM43 antigen(gene name synonym)|uniprotkb:Membrane inhibitor of reactive lysis(gene name synonym)|uniprotkb:20 kDa homologous restriction factor(gene name synonym)|uniprotkb:1F5 antigen(gene name synonym)|uniprotkb:MIC11(gene name synonym)|uniprotkb:MIN1(gene name synonym)|uniprotkb:MIN2(gene name synonym)|uniprotkb:MIN3(gene name synonym)|uniprotkb:MSK21(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Schiza et al. (2018) imex:IM-28077|pubmed:30097533 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-25505396|imex:IM-28077-7 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000131126(gene)|ensembl:ENST00000598265(transcript)|go:"GO:0001669"(acrosomal vesicle)|go:"GO:0002080"(acrosomal membrane)|go:"GO:0005576"(extracellular region)|go:"GO:0005886"(plasma membrane)|go:"GO:0007339"(binding of sperm to zona pellucida)|go:"GO:0009566"(fertilization)|go:"GO:0030317"(flagellated sperm motility)|go:"GO:0044853"(plasma membrane raft)|go:"GO:0046658"(anchored component of plasma membrane)|go:"GO:1901317"(regulation of flagellated sperm motility)|interpro:IPR016054(Ly-6 antigen / uPA receptor -like)|rcsb pdb:7BPR|reactome:R-HSA-163125|refseq:NP_001123483.1|refseq:NP_113639.4 refseq:NP_000602.1|refseq:NP_001120695.1|refseq:NP_001120697.1|refseq:NP_001120698.1|refseq:NP_001120699.1|refseq:NP_976074.1|refseq:NP_976075.1|refseq:NP_976076.1|ensembl:ENST00000395850(transcript)|ensembl:ENST00000415002(transcript)|ensembl:ENST00000437761(transcript)|ensembl:ENST00000445143(transcript)|ensembl:ENST00000527577(transcript)|ensembl:ENST00000642928(transcript)|ensembl:ENST00000651785(transcript)|ensembl:ENST00000652678(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001848"(complement binding)|go:"GO:0001971"(negative regulation of activation of membrane attack complex)|go:"GO:0005615"(extracellular space)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005886"(plasma membrane)|go:"GO:0005925"(focal adhesion)|go:"GO:0007166"(cell surface receptor signaling pathway)|go:"GO:0007596"(blood coagulation)|go:"GO:0009986"(cell surface)|go:"GO:0012507"(ER to Golgi transport vesicle membrane)|go:"GO:0016020"(membrane)|go:"GO:0030133"(transport vesicle)|go:"GO:0030449"(regulation of complement activation)|go:"GO:0031362"(anchored component of external side of plasma membrane)|go:"GO:0031982"(vesicle)|go:"GO:0033116"(endoplasmic reticulum-Golgi intermediate compartment membrane)|go:"GO:0035579"(specific granule membrane)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070821"(tertiary granule membrane)|go:"GO:1903659"(regulation of complement-dependent cytotoxicity)|interpro:IPR016054(Ly-6 antigen / uPA receptor -like)|interpro:IPR018363|interpro:IPR027101|mint:P13987|rcsb pdb:1CDQ|rcsb pdb:1CDR|rcsb pdb:1CDS|rcsb pdb:1ERG|rcsb pdb:1ERH|rcsb pdb:2J8B|rcsb pdb:2OFS|rcsb pdb:2UWR|rcsb pdb:2UX2|rcsb pdb:4BIK|rcsb pdb:5IMT|rcsb pdb:5IMY|rcsb pdb:6ZD0|reactome:R-HSA-204005|reactome:R-HSA-5694530|reactome:R-HSA-6798695|reactome:R-HSA-6807878|reactome:R-HSA-977606|ensembl:ENSG00000085063(gene)|ensembl:ENST00000351554(transcript) - - - comment:"Proteins significantly enriched by immunoprecipitation with 34ED556 (T1) anti-TEX101 antibody in human sperm cells from pre-vasectomy semen samples."|figure legend:Fig. 2B, supplemental Table S6|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-spermatozoa)|taxid:9606(Homo sapiens) - 2020/03/24 2020/04/07 rogid:ZE4tXTFi7lUCcIbCL4KHzY3a6xM9606 rogid:l93Yw04Ax0xODyPzjFqaaMvqBeM9606 rigid:TX1oljMyfkimcULEvhCJR/BRAW4 false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9BY14 uniprotkb:P13688 intact:EBI-12549378|ensembl:ENSP00000472769|uniprotkb:Q7L5R2|uniprotkb:Q9BPY7 intact:EBI-4314481|uniprotkb:Q13858|uniprotkb:Q13857|uniprotkb:Q13859|uniprotkb:Q15600|uniprotkb:Q069I7|uniprotkb:O60430|uniprotkb:A6NE38|uniprotkb:Q13860|uniprotkb:A8MY49|uniprotkb:Q13854|uniprotkb:Q15601|uniprotkb:Q96CA7|uniprotkb:Q5UB49|uniprotkb:Q7KYP5|uniprotkb:Q16170|uniprotkb:Q9UQV9|ensembl:ENSP00000161559 psi-mi:tx101_human(display_long)|uniprotkb:TEX101(gene name)|psi-mi:TEX101(display_short)|uniprotkb:Cell surface receptor NYD-SP8(gene name synonym)|uniprotkb:SGRG(gene name synonym)|uniprotkb:Scleroderma-associated autoantigen(gene name synonym)|uniprotkb:Spermatogenesis-related gene protein(gene name synonym)|uniprotkb:UNQ867/PRO1884(orf name) psi-mi:ceam1_human(display_long)|uniprotkb:CEACAM1(gene name)|psi-mi:CEACAM1(display_short)|uniprotkb:BGP(gene name synonym)|uniprotkb:BGP1(gene name synonym)|uniprotkb:Biliary glycoprotein 1(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Schiza et al. (2018) imex:IM-28077|pubmed:30097533 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-25505396|imex:IM-28077-7 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000131126(gene)|ensembl:ENST00000598265(transcript)|go:"GO:0001669"(acrosomal vesicle)|go:"GO:0002080"(acrosomal membrane)|go:"GO:0005576"(extracellular region)|go:"GO:0005886"(plasma membrane)|go:"GO:0007339"(binding of sperm to zona pellucida)|go:"GO:0009566"(fertilization)|go:"GO:0030317"(flagellated sperm motility)|go:"GO:0044853"(plasma membrane raft)|go:"GO:0046658"(anchored component of plasma membrane)|go:"GO:1901317"(regulation of flagellated sperm motility)|interpro:IPR016054(Ly-6 antigen / uPA receptor -like)|rcsb pdb:7BPR|reactome:R-HSA-163125|refseq:NP_001123483.1|refseq:NP_113639.4 refseq:NP_001020083.1|refseq:NP_001171742.1|refseq:NP_001171744.1|refseq:NP_001171745.1|refseq:NP_001192273.1|refseq:NP_001703.2|go:"GO:0031528"(microvillus membrane)|go:"GO:0032692"(negative regulation of interleukin-1 production)|go:"GO:0032869"(cellular response to insulin stimulus)|go:"GO:0035579"(specific granule membrane)|go:"GO:0035726"(common myeloid progenitor cell proliferation)|go:"GO:0038016"(insulin receptor internalization)|go:"GO:0038158"(granulocyte colony-stimulating factor signaling pathway)|go:"GO:0042058"(regulation of epidermal growth factor receptor signaling pathway)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043116"(negative regulation of vascular permeability)|go:"GO:0043318"(negative regulation of cytotoxic T cell degranulation)|go:"GO:0044319"(wound healing, spreading of cells)|go:"GO:0045601"(regulation of endothelial cell differentiation)|go:"GO:0045717"(negative regulation of fatty acid biosynthetic process)|go:"GO:0031005"(filamin binding)|reactome:R-HSA-202733|reactome:R-HSA-6798695|reactome:R-HSA-1566977|refseq:XP_011525508.1|go:"GO:0046983"(protein dimerization activity)|go:"GO:0050860"(negative regulation of T cell receptor signaling pathway)|go:"GO:0051055"(negative regulation of lipid biosynthetic process)|go:"GO:0060312"(regulation of blood vessel remodeling)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070372"(regulation of ERK1 and ERK2 cascade)|go:"GO:0070821"(tertiary granule membrane)|go:"GO:0090331"(negative regulation of platelet aggregation)|go:"GO:0098742"(cell-cell adhesion via plasma-membrane adhesion molecules)|go:"GO:1901143"(insulin catabolic process)|go:"GO:1903385"(regulation of homophilic cell adhesion)|go:"GO:1903670"(regulation of sprouting angiogenesis)|go:"GO:1990782"(protein tyrosine kinase binding)|go:"GO:2000346"(negative regulation of hepatocyte proliferation)|go:"GO:2001214"(positive regulation of vasculogenesis)|interpro:IPR003598(Immunoglobulin subtype 2)|interpro:IPR003599(Immunoglobulin subtype)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR013106(Immunoglobulin V-set)|interpro:IPR013151(Immunoglobulin)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR036179|mint:P13688|rcsb pdb:2GK2|rcsb pdb:4QXW|rcsb pdb:4WHD|rcsb pdb:5DZL|rcsb pdb:6AW2|rcsb pdb:6GBG|rcsb pdb:6GBH|rcsb pdb:6V3P|rcsb pdb:6XNO|rcsb pdb:6XNT|rcsb pdb:6XNW|rcsb pdb:6XO1|ensembl:ENSG00000079385(gene)|ensembl:ENST00000161559(transcript)|go:"GO:0001525"(angiogenesis)|go:"GO:0001558"(regulation of cell growth)|go:"GO:0001568"(blood vessel development)|go:"GO:0001915"(negative regulation of T cell mediated cytotoxicity)|go:"GO:0002859"(negative regulation of natural killer cell mediated cytotoxicity directed against tumor cell target)|go:"GO:0003779"(actin binding)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005912"(adherens junction)|go:"GO:0006469"(negative regulation of protein kinase activity)|go:"GO:0007155"(cell adhesion)|go:"GO:0007229"(integrin-mediated signaling pathway)|go:"GO:0009925"(basal plasma membrane)|go:"GO:0009986"(cell surface)|go:"GO:0010594"(regulation of endothelial cell migration)|go:"GO:0014066"(regulation of phosphatidylinositol 3-kinase signaling)|go:"GO:0015125"(bile acid transmembrane transporter activity)|go:"GO:0015721"(bile acid and bile salt transport)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0016328"(lateral plasma membrane)|go:"GO:0016477"(cell migration)|go:"GO:0007156"(homophilic cell adhesion via plasma membrane adhesion molecules)|go:"GO:0019900"(kinase binding)|go:"GO:0019903"(protein phosphatase binding)|go:"GO:0030054"(cell junction)|go:"GO:0030334"(regulation of cell migration)|go:"GO:0030658"(transport vesicle membrane)|go:"GO:0030853"(negative regulation of granulocyte differentiation)|dip:DIP-42683N - - - comment:"Proteins significantly enriched by immunoprecipitation with 34ED556 (T1) anti-TEX101 antibody in human sperm cells from pre-vasectomy semen samples."|figure legend:Fig. 2B, supplemental Table S6|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-spermatozoa)|taxid:9606(Homo sapiens) - 2020/03/24 2020/04/07 rogid:ZE4tXTFi7lUCcIbCL4KHzY3a6xM9606 rogid:M1gnNv8yCTCddhfx20lHL7WFvf49606 rigid:TX1oljMyfkimcULEvhCJR/BRAW4 false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9BY14 uniprotkb:O43451 intact:EBI-12549378|ensembl:ENSP00000472769|uniprotkb:Q7L5R2|uniprotkb:Q9BPY7 intact:EBI-2829774|uniprotkb:Q86UM5|uniprotkb:Q75ME7|uniprotkb:Q0VAX6|ensembl:ENSP00000447378|ensembl:ENSP00000482292 psi-mi:tx101_human(display_long)|uniprotkb:TEX101(gene name)|psi-mi:TEX101(display_short)|uniprotkb:Cell surface receptor NYD-SP8(gene name synonym)|uniprotkb:SGRG(gene name synonym)|uniprotkb:Scleroderma-associated autoantigen(gene name synonym)|uniprotkb:Spermatogenesis-related gene protein(gene name synonym)|uniprotkb:UNQ867/PRO1884(orf name) psi-mi:mga_human(display_long)|uniprotkb:MGAM(gene name)|psi-mi:MGAM(display_short)|uniprotkb:MGA(gene name synonym)|uniprotkb:MGAML(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Schiza et al. (2018) imex:IM-28077|pubmed:30097533 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-25505396|imex:IM-28077-7 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000131126(gene)|ensembl:ENST00000598265(transcript)|go:"GO:0001669"(acrosomal vesicle)|go:"GO:0002080"(acrosomal membrane)|go:"GO:0005576"(extracellular region)|go:"GO:0005886"(plasma membrane)|go:"GO:0007339"(binding of sperm to zona pellucida)|go:"GO:0009566"(fertilization)|go:"GO:0030317"(flagellated sperm motility)|go:"GO:0044853"(plasma membrane raft)|go:"GO:0046658"(anchored component of plasma membrane)|go:"GO:1901317"(regulation of flagellated sperm motility)|interpro:IPR016054(Ly-6 antigen / uPA receptor -like)|rcsb pdb:7BPR|reactome:R-HSA-163125|refseq:NP_001123483.1|refseq:NP_113639.4 refseq:NP_004659.2|ensembl:ENSG00000257335(gene)|ensembl:ENST00000549489(transcript)|ensembl:ENST00000620571(transcript)|go:"GO:0003824"(catalytic activity)|go:"GO:0004339"(glucan 1,4-alpha-glucosidase activity)|go:"GO:0004553"(hydrolase activity, hydrolyzing O-glycosyl compounds)|go:"GO:0004558"(alpha-1,4-glucosidase activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0005983"(starch catabolic process)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0030246"(carbohydrate binding)|go:"GO:0032450"(maltose alpha-glucosidase activity)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070821"(tertiary granule membrane)|go:"GO:0101003"(ficolin-1-rich granule membrane)|interpro:IPR000322(Glycoside hydrolase, family 31)|interpro:IPR000519(P-type trefoil)|interpro:IPR011013(Glycoside hydrolase-type carbohydrate-binding)|interpro:IPR013780(Glycosyl hydrolase, family 13, all-beta)|interpro:IPR017853(Glycoside hydrolase, catalytic core)|interpro:IPR017957|interpro:IPR030458|interpro:IPR030459|interpro:IPR031727|mint:O43451|rcsb pdb:2QLY|rcsb pdb:2QMJ|rcsb pdb:3CTT|rcsb pdb:3L4T|rcsb pdb:3L4U|rcsb pdb:3L4V|rcsb pdb:3L4W|rcsb pdb:3L4X|rcsb pdb:3L4Y|rcsb pdb:3L4Z|rcsb pdb:3TON|rcsb pdb:3TOP|reactome:R-HSA-189085|reactome:R-HSA-6798695 - - - comment:"Proteins significantly enriched by immunoprecipitation with 34ED556 (T1) anti-TEX101 antibody in human sperm cells from pre-vasectomy semen samples."|figure legend:Fig. 2B, supplemental Table S6|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-spermatozoa)|taxid:9606(Homo sapiens) - 2020/03/24 2020/04/07 rogid:ZE4tXTFi7lUCcIbCL4KHzY3a6xM9606 rogid:99L/qrsHlCvmngN9Oga9OTT0rvo9606 rigid:TX1oljMyfkimcULEvhCJR/BRAW4 false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9BY14 uniprotkb:Q9HDC9 intact:EBI-12549378|ensembl:ENSP00000472769|uniprotkb:Q7L5R2|uniprotkb:Q9BPY7 intact:EBI-723950|ensembl:ENSP00000217456|uniprotkb:Q6UVZ8|uniprotkb:Q9GZS8|uniprotkb:Q9NUB2|uniprotkb:A8K514|uniprotkb:B4DXG1 psi-mi:tx101_human(display_long)|uniprotkb:TEX101(gene name)|psi-mi:TEX101(display_short)|uniprotkb:Cell surface receptor NYD-SP8(gene name synonym)|uniprotkb:SGRG(gene name synonym)|uniprotkb:Scleroderma-associated autoantigen(gene name synonym)|uniprotkb:Spermatogenesis-related gene protein(gene name synonym)|uniprotkb:UNQ867/PRO1884(orf name) psi-mi:apmap_human(display_long)|uniprotkb:Protein BSCv(gene name synonym)|uniprotkb:APMAP(gene name)|psi-mi:APMAP(display_short)|uniprotkb:C20orf3(gene name synonym)|uniprotkb:UNQ1869/PRO4305(orf name) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Schiza et al. (2018) imex:IM-28077|pubmed:30097533 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-25505396|imex:IM-28077-7 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000131126(gene)|ensembl:ENST00000598265(transcript)|go:"GO:0001669"(acrosomal vesicle)|go:"GO:0002080"(acrosomal membrane)|go:"GO:0005576"(extracellular region)|go:"GO:0005886"(plasma membrane)|go:"GO:0007339"(binding of sperm to zona pellucida)|go:"GO:0009566"(fertilization)|go:"GO:0030317"(flagellated sperm motility)|go:"GO:0044853"(plasma membrane raft)|go:"GO:0046658"(anchored component of plasma membrane)|go:"GO:1901317"(regulation of flagellated sperm motility)|interpro:IPR016054(Ly-6 antigen / uPA receptor -like)|rcsb pdb:7BPR|reactome:R-HSA-163125|refseq:NP_001123483.1|refseq:NP_113639.4 refseq:NP_065392.1|ensembl:ENSG00000101474(gene)|ensembl:ENST00000217456(transcript)|go:"GO:0004064"(arylesterase activity)|go:"GO:0009058"(biosynthetic process)|go:"GO:0009986"(cell surface)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016844"(strictosidine synthase activity)|interpro:IPR011042(Six-bladed beta-propeller, TolB-like)|interpro:IPR018119|mint:Q9HDC9|refseq:XP_005260820.1 - - - comment:"Proteins significantly enriched by immunoprecipitation with 34ED556 (T1) anti-TEX101 antibody in human sperm cells from pre-vasectomy semen samples."|figure legend:Fig. 2B, supplemental Table S6|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-spermatozoa)|taxid:9606(Homo sapiens) - 2020/03/24 2020/04/07 rogid:ZE4tXTFi7lUCcIbCL4KHzY3a6xM9606 rogid:IRPAV+sieIBDPYsV4ypu35eSrkQ9606 rigid:TX1oljMyfkimcULEvhCJR/BRAW4 false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9BY14 uniprotkb:Q04609 intact:EBI-12549378|ensembl:ENSP00000472769|uniprotkb:Q7L5R2|uniprotkb:Q9BPY7 intact:EBI-1390372|uniprotkb:O43748|uniprotkb:Q16305|uniprotkb:Q9NP15|uniprotkb:Q9NYE2|uniprotkb:Q9P1P8|uniprotkb:B7Z312|uniprotkb:E9PDX8|uniprotkb:A9CB79|uniprotkb:B7Z343|uniprotkb:Q541A4|uniprotkb:Q8TAY3|uniprotkb:A4UU12|uniprotkb:D3DQS5|ensembl:ENSP00000256999 psi-mi:tx101_human(display_long)|uniprotkb:TEX101(gene name)|psi-mi:TEX101(display_short)|uniprotkb:Cell surface receptor NYD-SP8(gene name synonym)|uniprotkb:SGRG(gene name synonym)|uniprotkb:Scleroderma-associated autoantigen(gene name synonym)|uniprotkb:Spermatogenesis-related gene protein(gene name synonym)|uniprotkb:UNQ867/PRO1884(orf name) psi-mi:folh1_human(display_long)|uniprotkb:Glutamate carboxypeptidase II(gene name synonym)|uniprotkb:Membrane glutamate carboxypeptidase(gene name synonym)|uniprotkb:N-acetylated-alpha-linked acidic dipeptidase I(gene name synonym)|uniprotkb:Pteroylpoly-gamma-glutamate carboxypeptidase(gene name synonym)|uniprotkb:Folylpoly-gamma-glutamate carboxypeptidase(gene name synonym)|uniprotkb:Folate hydrolase 1(gene name synonym)|uniprotkb:Prostate-specific membrane antigen(gene name synonym)|uniprotkb:FOLH1(gene name)|psi-mi:FOLH1(display_short)|uniprotkb:FOLH(gene name synonym)|uniprotkb:NAALAD1(gene name synonym)|uniprotkb:PSM(gene name synonym)|uniprotkb:PSMA(gene name synonym)|uniprotkb:Cell growth-inhibiting gene 27 protein(gene name synonym)|uniprotkb:GIG27(orf name) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Schiza et al. (2018) imex:IM-28077|pubmed:30097533 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-25505396|imex:IM-28077-7 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000131126(gene)|ensembl:ENST00000598265(transcript)|go:"GO:0001669"(acrosomal vesicle)|go:"GO:0002080"(acrosomal membrane)|go:"GO:0005576"(extracellular region)|go:"GO:0005886"(plasma membrane)|go:"GO:0007339"(binding of sperm to zona pellucida)|go:"GO:0009566"(fertilization)|go:"GO:0030317"(flagellated sperm motility)|go:"GO:0044853"(plasma membrane raft)|go:"GO:0046658"(anchored component of plasma membrane)|go:"GO:1901317"(regulation of flagellated sperm motility)|interpro:IPR016054(Ly-6 antigen / uPA receptor -like)|rcsb pdb:7BPR|reactome:R-HSA-163125|refseq:NP_001123483.1|refseq:NP_113639.4 refseq:NP_001014986.1|refseq:NP_001180400.1|refseq:NP_001180401.1|refseq:NP_001180402.1|refseq:NP_004467.1|refseq:XP_016872923.1|refseq:XP_016872924.1|refseq:XP_016872926.1|refseq:XP_016872931.1|refseq:XP_016872932.1|refseq:XP_016872933.1|refseq:XP_016872934.1|refseq:XP_016872935.1|refseq:XP_016872936.1|refseq:XP_016872937.1|refseq:XP_016872925.1|ensembl:ENSG00000086205(gene)|ensembl:ENST00000256999(transcript)|go:"GO:0004180"(carboxypeptidase activity)|go:"GO:0004181"(metallocarboxypeptidase activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006508"(proteolysis)|go:"GO:0008233"(peptidase activity)|go:"GO:0009986"(cell surface)|go:"GO:0016020"(membrane)|go:"GO:0016805"(dipeptidase activity)|go:"GO:0035609"(C-terminal protein deglutamylation)|go:"GO:0046872"(metal ion binding)|go:"GO:0070062"(extracellular exosome)|go:"GO:1904492"(Ac-Asp-Glu binding)|go:"GO:1904493"("tetrahydrofolyl-poly(glutamate) polymer binding")|interpro:IPR003137(Protease-associated PA)|rcsb pdb:2PVW|interpro:IPR007365(Transferrin receptor-like, dimerisation)|interpro:IPR007484(Peptidase M28)|interpro:IPR036757|interpro:IPR039373|rcsb pdb:1Z8L|rcsb pdb:2C6C|rcsb pdb:2C6G|rcsb pdb:2C6P|rcsb pdb:2CIJ|rcsb pdb:2JBJ|rcsb pdb:2JBK|rcsb pdb:2OOT|rcsb pdb:2OR4|rcsb pdb:2XEF|rcsb pdb:2XEG|rcsb pdb:2PVV|rcsb pdb:2XEI|rcsb pdb:2XEJ|rcsb pdb:3BHX|rcsb pdb:3BI0|rcsb pdb:3BI1|rcsb pdb:3BXM|rcsb pdb:3D7D|rcsb pdb:3D7F|rcsb pdb:3D7G|rcsb pdb:3D7H|rcsb pdb:3IWW|rcsb pdb:3RBU|rcsb pdb:3SJE|rcsb pdb:3SJF|rcsb pdb:3SJG|rcsb pdb:3SJX|rcsb pdb:4JYW|rcsb pdb:4JZ0|rcsb pdb:4LQG|rcsb pdb:4MCP|rcsb pdb:4MCQ|rcsb pdb:4MCR|rcsb pdb:4NGM|rcsb pdb:4NGN|rcsb pdb:4NGP|rcsb pdb:4NGQ|rcsb pdb:4NGR|rcsb pdb:4NGS|rcsb pdb:4NGT|rcsb pdb:4OC0|rcsb pdb:4OC1|rcsb pdb:4OC2|rcsb pdb:4OC3|rcsb pdb:4OC4|rcsb pdb:4OC5|rcsb pdb:4MCS|rcsb pdb:4OME|rcsb pdb:4P44|rcsb pdb:4P45|rcsb pdb:4P4B|rcsb pdb:4P4D|rcsb pdb:4P4E|rcsb pdb:4P4F|rcsb pdb:4P4I|rcsb pdb:4P4J|rcsb pdb:4W9Y|rcsb pdb:4X3R|rcsb pdb:5D29|rcsb pdb:5ELY|rcsb pdb:5F09|rcsb pdb:5O5R|rcsb pdb:5O5T|rcsb pdb:5O5U|rcsb pdb:5OF0|rcsb pdb:6ETY|rcsb pdb:6EZ9|rcsb pdb:6F5L|rcsb pdb:6FE5|rcsb pdb:6H7Y|rcsb pdb:6H7Z|rcsb pdb:6HKJ|rcsb pdb:6HKZ|rcsb pdb:6RBC|rcsb pdb:6RTI|rcsb pdb:6S1X|rcsb pdb:6SGP|rcsb pdb:6SKH|reactome:R-HSA-8963693 - - - comment:"Proteins significantly enriched by immunoprecipitation with 34ED556 (T1) anti-TEX101 antibody in human sperm cells from pre-vasectomy semen samples."|figure legend:Fig. 2B, supplemental Table S6|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-spermatozoa)|taxid:9606(Homo sapiens) - 2020/03/24 2020/04/07 rogid:ZE4tXTFi7lUCcIbCL4KHzY3a6xM9606 rogid:qclBRSa6uxBaG+vzziop8uEuoDU9606 rigid:TX1oljMyfkimcULEvhCJR/BRAW4 false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9BY14 uniprotkb:O43653 intact:EBI-12549378|ensembl:ENSP00000472769|uniprotkb:Q7L5R2|uniprotkb:Q9BPY7 intact:EBI-14060095|ensembl:ENSP00000301258|uniprotkb:Q6UW92 psi-mi:tx101_human(display_long)|uniprotkb:TEX101(gene name)|psi-mi:TEX101(display_short)|uniprotkb:Cell surface receptor NYD-SP8(gene name synonym)|uniprotkb:SGRG(gene name synonym)|uniprotkb:Scleroderma-associated autoantigen(gene name synonym)|uniprotkb:Spermatogenesis-related gene protein(gene name synonym)|uniprotkb:UNQ867/PRO1884(orf name) psi-mi:psca_human(display_long)|uniprotkb:PSCA(gene name)|psi-mi:PSCA(display_short)|uniprotkb:UNQ206/PRO232(orf name) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Schiza et al. (2018) imex:IM-28077|pubmed:30097533 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-25505396|imex:IM-28077-7 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000131126(gene)|ensembl:ENST00000598265(transcript)|go:"GO:0001669"(acrosomal vesicle)|go:"GO:0002080"(acrosomal membrane)|go:"GO:0005576"(extracellular region)|go:"GO:0005886"(plasma membrane)|go:"GO:0007339"(binding of sperm to zona pellucida)|go:"GO:0009566"(fertilization)|go:"GO:0030317"(flagellated sperm motility)|go:"GO:0044853"(plasma membrane raft)|go:"GO:0046658"(anchored component of plasma membrane)|go:"GO:1901317"(regulation of flagellated sperm motility)|interpro:IPR016054(Ly-6 antigen / uPA receptor -like)|rcsb pdb:7BPR|reactome:R-HSA-163125|refseq:NP_001123483.1|refseq:NP_113639.4 ensembl:ENSG00000167653(gene)|ensembl:ENST00000301258(transcript)|go:"GO:0005576"(extracellular region)|go:"GO:0005886"(plasma membrane)|go:"GO:0031225"(anchored component of membrane)|go:"GO:0033130"(acetylcholine receptor binding)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070373"(negative regulation of ERK1 and ERK2 cascade)|go:"GO:0099601"(regulation of neurotransmitter receptor activity)|interpro:IPR016054(Ly-6 antigen / uPA receptor -like)|reactome:R-HSA-163125|refseq:NP_005663.2 - - - comment:"Proteins significantly enriched by immunoprecipitation with 34ED556 (T1) anti-TEX101 antibody in human sperm cells from pre-vasectomy semen samples."|figure legend:Fig. 2B, supplemental Table S6|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-spermatozoa)|taxid:9606(Homo sapiens) - 2020/03/24 2020/04/07 rogid:ZE4tXTFi7lUCcIbCL4KHzY3a6xM9606 rogid:aT88EpP4jcXsudBPbqw8UYUf29U9606 rigid:TX1oljMyfkimcULEvhCJR/BRAW4 false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9BY14 uniprotkb:P13073 intact:EBI-12549378|ensembl:ENSP00000472769|uniprotkb:Q7L5R2|uniprotkb:Q9BPY7 intact:EBI-1056574|uniprotkb:B2R4J2|uniprotkb:D3DUM7|uniprotkb:Q6P666|ensembl:ENSP00000253452|ensembl:ENSP00000457015|ensembl:ENSP00000457513 psi-mi:tx101_human(display_long)|uniprotkb:TEX101(gene name)|psi-mi:TEX101(display_short)|uniprotkb:Cell surface receptor NYD-SP8(gene name synonym)|uniprotkb:SGRG(gene name synonym)|uniprotkb:Scleroderma-associated autoantigen(gene name synonym)|uniprotkb:Spermatogenesis-related gene protein(gene name synonym)|uniprotkb:UNQ867/PRO1884(orf name) psi-mi:cox41_human(display_long)|uniprotkb:COX4I1(gene name)|psi-mi:COX4I1(display_short)|uniprotkb:COX4(gene name synonym)|uniprotkb:Cytochrome c oxidase subunit IV isoform 1(gene name synonym)|uniprotkb:Cytochrome c oxidase polypeptide IV(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Schiza et al. (2018) imex:IM-28077|pubmed:30097533 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-25505396|imex:IM-28077-7 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000131126(gene)|ensembl:ENST00000598265(transcript)|go:"GO:0001669"(acrosomal vesicle)|go:"GO:0002080"(acrosomal membrane)|go:"GO:0005576"(extracellular region)|go:"GO:0005886"(plasma membrane)|go:"GO:0007339"(binding of sperm to zona pellucida)|go:"GO:0009566"(fertilization)|go:"GO:0030317"(flagellated sperm motility)|go:"GO:0044853"(plasma membrane raft)|go:"GO:0046658"(anchored component of plasma membrane)|go:"GO:1901317"(regulation of flagellated sperm motility)|interpro:IPR016054(Ly-6 antigen / uPA receptor -like)|rcsb pdb:7BPR|reactome:R-HSA-163125|refseq:NP_001123483.1|refseq:NP_113639.4 refseq:NP_001852.1|refseq:NP_001305726.1|refseq:NP_001305731.1|refseq:NP_001305715.1|refseq:NP_001305717.1|refseq:NP_001305723.1|ensembl:ENSG00000131143(gene)|ensembl:ENST00000253452(transcript)|ensembl:ENST00000561569(transcript)|ensembl:ENST00000562336(transcript)|go:"GO:0004129"(cytochrome-c oxidase activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005751"(mitochondrial respiratory chain complex IV)|go:"GO:0005829"(cytosol)|go:"GO:0006091"(generation of precursor metabolites and energy)|go:"GO:0006123"(mitochondrial electron transport, cytochrome c to oxygen)|go:"GO:0007584"(response to nutrient)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|interpro:IPR004203(Cytochrome c oxidase subunit IV)|interpro:IPR013288(Cytochrome c oxidase subunit 4)|interpro:IPR036639|mint:P13073|rcsb pdb:5Z62|reactome:R-HSA-5628897|reactome:R-HSA-611105|reactome:R-HSA-9707564 - - - comment:"Proteins significantly enriched by immunoprecipitation with 34ED556 (T1) anti-TEX101 antibody in human sperm cells from pre-vasectomy semen samples."|figure legend:Fig. 2B, supplemental Table S6|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-spermatozoa)|taxid:9606(Homo sapiens) - 2020/03/24 2020/04/07 rogid:ZE4tXTFi7lUCcIbCL4KHzY3a6xM9606 rogid:7TbisLJIPPlFeZNNXqP9SciPjLw9606 rigid:TX1oljMyfkimcULEvhCJR/BRAW4 false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9BY14 uniprotkb:P12821 intact:EBI-12549378|ensembl:ENSP00000472769|uniprotkb:Q7L5R2|uniprotkb:Q9BPY7 intact:EBI-9512350|uniprotkb:B0LPF0|uniprotkb:B4DXI3|uniprotkb:E7EU16|uniprotkb:P22966|uniprotkb:Q53YX9|uniprotkb:Q59GY8|uniprotkb:Q7M4L4|ensembl:ENSP00000290866 psi-mi:tx101_human(display_long)|uniprotkb:TEX101(gene name)|psi-mi:TEX101(display_short)|uniprotkb:Cell surface receptor NYD-SP8(gene name synonym)|uniprotkb:SGRG(gene name synonym)|uniprotkb:Scleroderma-associated autoantigen(gene name synonym)|uniprotkb:Spermatogenesis-related gene protein(gene name synonym)|uniprotkb:UNQ867/PRO1884(orf name) psi-mi:ace_human(display_long)|uniprotkb:ACE(gene name)|psi-mi:ACE(display_short)|uniprotkb:DCP(gene name synonym)|uniprotkb:DCP1(gene name synonym)|uniprotkb:Dipeptidyl carboxypeptidase I(gene name synonym)|uniprotkb:Kininase II(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Schiza et al. (2018) imex:IM-28077|pubmed:30097533 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-25505396|imex:IM-28077-7 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000131126(gene)|ensembl:ENST00000598265(transcript)|go:"GO:0001669"(acrosomal vesicle)|go:"GO:0002080"(acrosomal membrane)|go:"GO:0005576"(extracellular region)|go:"GO:0005886"(plasma membrane)|go:"GO:0007339"(binding of sperm to zona pellucida)|go:"GO:0009566"(fertilization)|go:"GO:0030317"(flagellated sperm motility)|go:"GO:0044853"(plasma membrane raft)|go:"GO:0046658"(anchored component of plasma membrane)|go:"GO:1901317"(regulation of flagellated sperm motility)|interpro:IPR016054(Ly-6 antigen / uPA receptor -like)|rcsb pdb:7BPR|reactome:R-HSA-163125|refseq:NP_001123483.1|refseq:NP_113639.4 refseq:NP_000780.1|refseq:NP_001171528.1|refseq:NP_690043.1|ensembl:ENSG00000159640(gene)|ensembl:ENST00000290866(transcript)|go:"GO:0001822"(kidney development)|go:"GO:0001974"(blood vessel remodeling)|go:"GO:0002003"(angiotensin maturation)|go:"GO:0002019"(regulation of renal output by angiotensin)|go:"GO:0002446"(neutrophil mediated immunity)|go:"GO:0002474"(antigen processing and presentation of peptide antigen via MHC class I)|go:"GO:0003081"(regulation of systemic arterial blood pressure by renin-angiotensin)|go:"GO:0003084"(positive regulation of systemic arterial blood pressure)|go:"GO:0003779"(actin binding)|go:"GO:0004175"(endopeptidase activity)|go:"GO:0004180"(carboxypeptidase activity)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0005764"(lysosome)|go:"GO:0005768"(endosome)|go:"GO:0005886"(plasma membrane)|go:"GO:0006508"(proteolysis)|go:"GO:0007283"(spermatogenesis)|go:"GO:0008217"(regulation of blood pressure)|go:"GO:0008237"(metallopeptidase activity)|go:"GO:0008238"(exopeptidase activity)|go:"GO:0008240"(tripeptidyl-peptidase activity)|go:"GO:0008241"(peptidyl-dipeptidase activity)|go:"GO:0008270"(zinc ion binding)|go:"GO:0009897"(external side of plasma membrane)|go:"GO:0010608"(posttranscriptional regulation of gene expression)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0014910"(regulation of smooth muscle cell migration)|go:"GO:0016021"(integral component of membrane)|go:"GO:0019229"(regulation of vasoconstriction)|go:"GO:0031404"(chloride ion binding)|go:"GO:0031434"(mitogen-activated protein kinase kinase binding)|go:"GO:0031711"(bradykinin receptor binding)|go:"GO:0032091"(negative regulation of protein binding)|go:"GO:0032092"(positive regulation of protein binding)|go:"GO:0032943"(mononuclear cell proliferation)|go:"GO:0042447"(hormone catabolic process)|go:"GO:0043171"(peptide catabolic process)|go:"GO:0050435"(amyloid-beta metabolic process)|go:"GO:0050482"(arachidonic acid secretion)|go:"GO:0051019"(mitogen-activated protein kinase binding)|go:"GO:0060047"(heart contraction)|go:"GO:0060177"(regulation of angiotensin metabolic process)|go:"GO:0060218"(hematopoietic stem cell differentiation)|go:"GO:0061098"(positive regulation of protein tyrosine kinase activity)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070573"(metallodipeptidase activity)|go:"GO:0071838"(cell proliferation in bone marrow)|go:"GO:0097746"(blood vessel diameter maintenance)|go:"GO:1900086"(positive regulation of peptidyl-tyrosine autophosphorylation)|go:"GO:1902033"(regulation of hematopoietic stem cell proliferation)|go:"GO:1903597"(negative regulation of gap junction assembly)|go:"GO:2000170"(positive regulation of peptidyl-cysteine S-nitrosylation)|interpro:IPR001548(Peptidase M2, peptidyl-dipeptidase A)|mint:P12821|rcsb pdb:1O86|rcsb pdb:1O8A|rcsb pdb:1UZE|rcsb pdb:1UZF|rcsb pdb:2C6F|rcsb pdb:2C6N|rcsb pdb:2IUL|rcsb pdb:2IUX|rcsb pdb:2OC2|rcsb pdb:2XY9|rcsb pdb:2XYD|rcsb pdb:2YDM|rcsb pdb:3BKK|rcsb pdb:3BKL|rcsb pdb:3L3N|rcsb pdb:3NXQ|rcsb pdb:4APH|rcsb pdb:4APJ|rcsb pdb:4BXK|rcsb pdb:4BZR|rcsb pdb:4BZS|rcsb pdb:4C2N|rcsb pdb:4C2O|rcsb pdb:4C2P|rcsb pdb:4C2Q|rcsb pdb:4C2R|rcsb pdb:4CA5|rcsb pdb:4CA6|rcsb pdb:4UFA|rcsb pdb:4UFB|rcsb pdb:5AM8|rcsb pdb:5AM9|rcsb pdb:5AMA|rcsb pdb:5AMB|rcsb pdb:5AMC|rcsb pdb:6EN5|rcsb pdb:6EN6|rcsb pdb:6F9R|rcsb pdb:6F9T|rcsb pdb:6F9U|rcsb pdb:6F9V|rcsb pdb:6H5W|rcsb pdb:6H5X|rcsb pdb:6QS1|rcsb pdb:6TT1|rcsb pdb:6TT3|rcsb pdb:6TT4|rcsb pdb:6ZPQ|rcsb pdb:6ZPT|rcsb pdb:6ZPU|reactome:R-HSA-2022377 - - - comment:"Proteins significantly enriched by immunoprecipitation with 34ED556 (T1) anti-TEX101 antibody in human sperm cells from pre-vasectomy semen samples."|figure legend:Fig. 2B, supplemental Table S6|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-spermatozoa)|taxid:9606(Homo sapiens) - 2020/03/24 2020/04/07 rogid:ZE4tXTFi7lUCcIbCL4KHzY3a6xM9606 rogid:Ta44N/vjlStlVIzNX634OjHzyrM9606 rigid:TX1oljMyfkimcULEvhCJR/BRAW4 false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9BY14 uniprotkb:Q8N6Q3 intact:EBI-12549378|ensembl:ENSP00000472769|uniprotkb:Q7L5R2|uniprotkb:Q9BPY7 intact:EBI-747170|uniprotkb:Q711Q2|uniprotkb:Q8NCV9|uniprotkb:Q96QH1|uniprotkb:Q9HDA5 psi-mi:tx101_human(display_long)|uniprotkb:TEX101(gene name)|psi-mi:TEX101(display_short)|uniprotkb:Cell surface receptor NYD-SP8(gene name synonym)|uniprotkb:SGRG(gene name synonym)|uniprotkb:Scleroderma-associated autoantigen(gene name synonym)|uniprotkb:Spermatogenesis-related gene protein(gene name synonym)|uniprotkb:UNQ867/PRO1884(orf name) psi-mi:cd177_human(display_long)|uniprotkb:Polycythemia rubra vera protein 1(gene name synonym)|uniprotkb:NB1 glycoprotein(gene name synonym)|uniprotkb:Human neutrophil alloantigen 2a(gene name synonym)|uniprotkb:CD177(gene name)|psi-mi:CD177(display_short)|uniprotkb:NB1(gene name synonym)|uniprotkb:PRV1(gene name synonym)|uniprotkb:UNQ595/PRO1181(orf name) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Schiza et al. (2018) imex:IM-28077|pubmed:30097533 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-25505396|imex:IM-28077-7 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000131126(gene)|ensembl:ENST00000598265(transcript)|go:"GO:0001669"(acrosomal vesicle)|go:"GO:0002080"(acrosomal membrane)|go:"GO:0005576"(extracellular region)|go:"GO:0005886"(plasma membrane)|go:"GO:0007339"(binding of sperm to zona pellucida)|go:"GO:0009566"(fertilization)|go:"GO:0030317"(flagellated sperm motility)|go:"GO:0044853"(plasma membrane raft)|go:"GO:0046658"(anchored component of plasma membrane)|go:"GO:1901317"(regulation of flagellated sperm motility)|interpro:IPR016054(Ly-6 antigen / uPA receptor -like)|rcsb pdb:7BPR|reactome:R-HSA-163125|refseq:NP_001123483.1|refseq:NP_113639.4 refseq:NP_065139.2|interpro:IPR016054(Ly-6 antigen / uPA receptor -like)|reactome:R-HSA-140875|reactome:R-HSA-202733|go:"GO:0002020"(protease binding)|go:"GO:0005178"(integrin binding)|go:"GO:0005886"(plasma membrane)|go:"GO:0007155"(cell adhesion)|go:"GO:0007159"(leukocyte cell-cell adhesion)|go:"GO:0030027"(lamellipodium)|go:"GO:0030100"(regulation of endocytosis)|go:"GO:0030667"(secretory granule membrane)|go:"GO:0032930"(positive regulation of superoxide anion generation)|go:"GO:0034394"(protein localization to cell surface)|go:"GO:0035579"(specific granule membrane)|go:"GO:0043315"(positive regulation of neutrophil degranulation)|go:"GO:0044853"(plasma membrane raft)|go:"GO:0045087"(innate immune response)|go:"GO:0045217"(cell-cell junction maintenance)|go:"GO:0046658"(anchored component of plasma membrane)|go:"GO:0048306"(calcium-dependent protein binding)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070821"(tertiary granule membrane)|go:"GO:0072672"(neutrophil extravasation)|go:"GO:0098742"(cell-cell adhesion via plasma-membrane adhesion molecules)|go:"GO:1990266"(neutrophil migration)|go:"GO:2001044"(regulation of integrin-mediated signaling pathway)|reactome:R-HSA-6798695 - - - comment:"Proteins significantly enriched by immunoprecipitation with 34ED556 (T1) anti-TEX101 antibody in human sperm cells from pre-vasectomy semen samples."|figure legend:Fig. 2B, supplemental Table S6|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-spermatozoa)|taxid:9606(Homo sapiens) - 2020/03/24 2020/04/07 rogid:ZE4tXTFi7lUCcIbCL4KHzY3a6xM9606 rogid:uEXp4MCku095cvEhkd6wZyz5a/09606 rigid:TX1oljMyfkimcULEvhCJR/BRAW4 false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9BY14 uniprotkb:P27487 intact:EBI-12549378|ensembl:ENSP00000472769|uniprotkb:Q7L5R2|uniprotkb:Q9BPY7 intact:EBI-2871277|uniprotkb:Q53TN1|ensembl:ENSP00000353731 psi-mi:tx101_human(display_long)|uniprotkb:TEX101(gene name)|psi-mi:TEX101(display_short)|uniprotkb:Cell surface receptor NYD-SP8(gene name synonym)|uniprotkb:SGRG(gene name synonym)|uniprotkb:Scleroderma-associated autoantigen(gene name synonym)|uniprotkb:Spermatogenesis-related gene protein(gene name synonym)|uniprotkb:UNQ867/PRO1884(orf name) psi-mi:dpp4_human(display_long)|uniprotkb:DPP4(gene name)|psi-mi:DPP4(display_short)|uniprotkb:ADCP2(gene name synonym)|uniprotkb:CD26(gene name synonym)|uniprotkb:ADABP(gene name synonym)|uniprotkb:Adenosine deaminase complexing protein 2(gene name synonym)|uniprotkb:Dipeptidyl peptidase IV(gene name synonym)|uniprotkb:T-cell activation antigen CD26(gene name synonym)|uniprotkb:TP103(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Schiza et al. (2018) imex:IM-28077|pubmed:30097533 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-25505396|imex:IM-28077-7 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000131126(gene)|ensembl:ENST00000598265(transcript)|go:"GO:0001669"(acrosomal vesicle)|go:"GO:0002080"(acrosomal membrane)|go:"GO:0005576"(extracellular region)|go:"GO:0005886"(plasma membrane)|go:"GO:0007339"(binding of sperm to zona pellucida)|go:"GO:0009566"(fertilization)|go:"GO:0030317"(flagellated sperm motility)|go:"GO:0044853"(plasma membrane raft)|go:"GO:0046658"(anchored component of plasma membrane)|go:"GO:1901317"(regulation of flagellated sperm motility)|interpro:IPR016054(Ly-6 antigen / uPA receptor -like)|rcsb pdb:7BPR|reactome:R-HSA-163125|refseq:NP_001123483.1|refseq:NP_113639.4 refseq:NP_001926.2|dip:DIP-351N|ensembl:ENSG00000197635(gene)|ensembl:ENST00000360534(transcript)|go:"GO:0001618"(virus receptor activity)|go:"GO:0001662"(behavioral fear response)|go:"GO:0001666"(response to hypoxia)|go:"GO:0002020"(protease binding)|go:"GO:0004177"(aminopeptidase activity)|go:"GO:0004252"(serine-type endopeptidase activity)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005886"(plasma membrane)|go:"GO:0005925"(focal adhesion)|go:"GO:0006508"(proteolysis)|go:"GO:0007155"(cell adhesion)|go:"GO:0008236"(serine-type peptidase activity)|go:"GO:0008239"(dipeptidyl-peptidase activity)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0009986"(cell surface)|go:"GO:0010716"(negative regulation of extracellular matrix disassembly)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0030027"(lamellipodium)|go:"GO:0030139"(endocytic vesicle)|go:"GO:0031258"(lamellipodium membrane)|go:"GO:0031295"(T cell costimulation)|go:"GO:0033632"(regulation of cell-cell adhesion mediated by integrin)|go:"GO:0035641"(locomotory exploration behavior)|go:"GO:0036343"(psychomotor behavior)|go:"GO:0042110"(T cell activation)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043542"(endothelial cell migration)|go:"GO:0045121"(membrane raft)|go:"GO:0045499"(chemorepellent activity)|go:"GO:0046581"(intercellular canaliculus)|go:"GO:0050796"(regulation of insulin secretion)|go:"GO:0070062"(extracellular exosome)|go:"GO:0090024"(negative regulation of neutrophil chemotaxis)|interpro:IPR001375(Peptidase S9, prolyl oligopeptidase active site region)|interpro:IPR002469(Peptidase S9B, dipeptidylpeptidase IV N-terminal)|interpro:IPR002471(Peptidase S9, serine active site)|interpro:IPR029058|mint:P27487|rcsb pdb:1J2E|rcsb pdb:1N1M|rcsb pdb:1NU6|rcsb pdb:1NU8|rcsb pdb:1PFQ|rcsb pdb:1R9M|rcsb pdb:1R9N|rcsb pdb:1RWQ|rcsb pdb:1TK3|rcsb pdb:1TKR|rcsb pdb:1U8E|rcsb pdb:1W1I|rcsb pdb:1WCY|rcsb pdb:1X70|rcsb pdb:2AJL|rcsb pdb:2BGN|rcsb pdb:2BGR|rcsb pdb:2BUB|rcsb pdb:2FJP|rcsb pdb:2G5P|rcsb pdb:2G5T|rcsb pdb:2G63|rcsb pdb:2HHA|rcsb pdb:2I03|rcsb pdb:2I78|rcsb pdb:2IIV|rcsb pdb:2JID|rcsb pdb:2OAG|rcsb pdb:2OGZ|rcsb pdb:2OLE|rcsb pdb:2ONC|rcsb pdb:2OPH|rcsb pdb:2OQI|rcsb pdb:2OQV|rcsb pdb:2P8S|rcsb pdb:2QJR|rcsb pdb:2QKY|rcsb pdb:2QOE|rcsb pdb:2QT9|rcsb pdb:2IIT|rcsb pdb:2QTB|rcsb pdb:2RGU|rcsb pdb:2RIP|rcsb pdb:3BJM|rcsb pdb:3C43|rcsb pdb:3C45|rcsb pdb:3CCB|rcsb pdb:3CCC|rcsb pdb:3D4L|rcsb pdb:3EIO|rcsb pdb:3F8S|rcsb pdb:3G0B|rcsb pdb:3G0C|rcsb pdb:3G0D|rcsb pdb:3G0G|rcsb pdb:3H0C|rcsb pdb:3HAB|rcsb pdb:3HAC|rcsb pdb:3KWF|rcsb pdb:3KWJ|rcsb pdb:3NOX|rcsb pdb:3O95|rcsb pdb:3O9V|rcsb pdb:3OC0|rcsb pdb:3OPM|rcsb pdb:3Q0T|rcsb pdb:3Q8W|rcsb pdb:3SWW|rcsb pdb:3SX4|rcsb pdb:3VJK|rcsb pdb:3VJL|rcsb pdb:3VJM|rcsb pdb:3W2T|rcsb pdb:3WQH|rcsb pdb:4A5S|rcsb pdb:4DSA|rcsb pdb:4DSZ|rcsb pdb:4DTC|rcsb pdb:4G1F|rcsb pdb:4J3J|rcsb pdb:4JH0|rcsb pdb:4KR0|rcsb pdb:4L72|rcsb pdb:4LKO|rcsb pdb:4N8D|rcsb pdb:4N8E|rcsb pdb:4PNZ|rcsb pdb:4PV7|rcsb pdb:4QZV|rcsb pdb:5I7U|rcsb pdb:5ISM|rcsb pdb:5J3J|rcsb pdb:5KBY|rcsb pdb:5T4B|rcsb pdb:5T4E|rcsb pdb:5T4F|rcsb pdb:5T4H|rcsb pdb:5Y7H|rcsb pdb:5Y7J|rcsb pdb:5Y7K|rcsb pdb:5ZID|rcsb pdb:6B1E|rcsb pdb:6B1O|reactome:R-HSA-381771|reactome:R-HSA-400511|rcsb pdb:3QBJ - - - comment:"Proteins significantly enriched by immunoprecipitation with 34ED556 (T1) anti-TEX101 antibody in human sperm cells from pre-vasectomy semen samples."|figure legend:Fig. 2B, supplemental Table S6|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-spermatozoa)|taxid:9606(Homo sapiens) - 2020/03/24 2020/04/07 rogid:ZE4tXTFi7lUCcIbCL4KHzY3a6xM9606 rogid:D8cgqdBbAfEQk+G2GhDuJvrkBcE9606 rigid:TX1oljMyfkimcULEvhCJR/BRAW4 false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9BY14 uniprotkb:Q9H4B8 intact:EBI-12549378|ensembl:ENSP00000472769|uniprotkb:Q7L5R2|uniprotkb:Q9BPY7 intact:EBI-20843342|ensembl:ENSP00000268793|uniprotkb:B3KQ48|uniprotkb:Q6PEZ5|uniprotkb:Q6UXE4 psi-mi:tx101_human(display_long)|uniprotkb:TEX101(gene name)|psi-mi:TEX101(display_short)|uniprotkb:Cell surface receptor NYD-SP8(gene name synonym)|uniprotkb:SGRG(gene name synonym)|uniprotkb:Scleroderma-associated autoantigen(gene name synonym)|uniprotkb:Spermatogenesis-related gene protein(gene name synonym)|uniprotkb:UNQ867/PRO1884(orf name) psi-mi:dpep3_human(display_long)|uniprotkb:DPEP3(gene name)|psi-mi:DPEP3(display_short)|uniprotkb:UNQ834/PRO1772(orf name) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Schiza et al. (2018) imex:IM-28077|pubmed:30097533 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-25505396|imex:IM-28077-7 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000131126(gene)|ensembl:ENST00000598265(transcript)|go:"GO:0001669"(acrosomal vesicle)|go:"GO:0002080"(acrosomal membrane)|go:"GO:0005576"(extracellular region)|go:"GO:0005886"(plasma membrane)|go:"GO:0007339"(binding of sperm to zona pellucida)|go:"GO:0009566"(fertilization)|go:"GO:0030317"(flagellated sperm motility)|go:"GO:0044853"(plasma membrane raft)|go:"GO:0046658"(anchored component of plasma membrane)|go:"GO:1901317"(regulation of flagellated sperm motility)|interpro:IPR016054(Ly-6 antigen / uPA receptor -like)|rcsb pdb:7BPR|reactome:R-HSA-163125|refseq:NP_001123483.1|refseq:NP_113639.4 ensembl:ENSG00000141096(gene)|ensembl:ENST00000268793(transcript)|go:"GO:0001669"(acrosomal vesicle)|go:"GO:0005886"(plasma membrane)|go:"GO:0016805"(dipeptidase activity)|go:"GO:0031225"(anchored component of membrane)|go:"GO:0046872"(metal ion binding)|go:"GO:0070573"(metallodipeptidase activity)|interpro:IPR000180(Peptidase M19, renal dipeptidase, active site)|interpro:IPR008257(Peptidase M19, renal dipeptidase)|interpro:IPR028531|interpro:IPR032466|rcsb pdb:6VGO|rcsb pdb:6VGR|reactome:R-HSA-2142691|reactome:R-HSA-5423646|reactome:R-HSA-9664535|refseq:NP_001123230.1|refseq:NP_071752.3 - - - comment:"Proteins significantly enriched by immunoprecipitation with 34ED556 (T1) anti-TEX101 antibody in human sperm cells from pre-vasectomy semen samples."|figure legend:Fig. 2B, supplemental Table S6|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-spermatozoa)|taxid:9606(Homo sapiens) - 2020/03/24 2020/04/07 rogid:ZE4tXTFi7lUCcIbCL4KHzY3a6xM9606 rogid:wSsO6DP0LPkeh39DF/dAvEktuTE9606 rigid:TX1oljMyfkimcULEvhCJR/BRAW4 false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9BY14 uniprotkb:P15144 intact:EBI-12549378|ensembl:ENSP00000472769|uniprotkb:Q7L5R2|uniprotkb:Q9BPY7 intact:EBI-2563898|uniprotkb:Q16728|uniprotkb:Q9UCE0|uniprotkb:Q8IVH3|uniprotkb:Q8IUK3|uniprotkb:Q6GT90|ensembl:ENSP00000300060|ensembl:ENSP00000452934|ensembl:ENSP00000453413|ensembl:ENSP00000502886 psi-mi:tx101_human(display_long)|uniprotkb:TEX101(gene name)|psi-mi:TEX101(display_short)|uniprotkb:Cell surface receptor NYD-SP8(gene name synonym)|uniprotkb:SGRG(gene name synonym)|uniprotkb:Scleroderma-associated autoantigen(gene name synonym)|uniprotkb:Spermatogenesis-related gene protein(gene name synonym)|uniprotkb:UNQ867/PRO1884(orf name) psi-mi:ampn_human(display_long)|uniprotkb:APN(gene name synonym)|uniprotkb:CD13(gene name synonym)|uniprotkb:PEPN(gene name synonym)|uniprotkb:Alanyl aminopeptidase(gene name synonym)|uniprotkb:Microsomal aminopeptidase(gene name synonym)|uniprotkb:Aminopeptidase M(gene name synonym)|uniprotkb:gp150(gene name synonym)|uniprotkb:Myeloid plasma membrane glycoprotein CD13(gene name synonym)|uniprotkb:ANPEP(gene name)|psi-mi:ANPEP(display_short) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Schiza et al. (2018) imex:IM-28077|pubmed:30097533 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-25505396|imex:IM-28077-7 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000131126(gene)|ensembl:ENST00000598265(transcript)|go:"GO:0001669"(acrosomal vesicle)|go:"GO:0002080"(acrosomal membrane)|go:"GO:0005576"(extracellular region)|go:"GO:0005886"(plasma membrane)|go:"GO:0007339"(binding of sperm to zona pellucida)|go:"GO:0009566"(fertilization)|go:"GO:0030317"(flagellated sperm motility)|go:"GO:0044853"(plasma membrane raft)|go:"GO:0046658"(anchored component of plasma membrane)|go:"GO:1901317"(regulation of flagellated sperm motility)|interpro:IPR016054(Ly-6 antigen / uPA receptor -like)|rcsb pdb:7BPR|reactome:R-HSA-163125|refseq:NP_001123483.1|refseq:NP_113639.4 refseq:NP_001141.2|refseq:XP_011519775.1|ensembl:ENSG00000166825(gene)|ensembl:ENST00000300060(transcript)|ensembl:ENST00000559874(transcript)|ensembl:ENST00000560137(transcript)|ensembl:ENST00000679248(transcript)|go:"GO:0001525"(angiogenesis)|go:"GO:0001618"(virus receptor activity)|go:"GO:0004177"(aminopeptidase activity)|go:"GO:0005615"(extracellular space)|go:"GO:0005737"(cytoplasm)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005793"(endoplasmic reticulum-Golgi intermediate compartment)|go:"GO:0005886"(plasma membrane)|go:"GO:0006508"(proteolysis)|go:"GO:0007165"(signal transduction)|go:"GO:0008217"(regulation of blood pressure)|go:"GO:0008237"(metallopeptidase activity)|go:"GO:0008270"(zinc ion binding)|go:"GO:0009897"(external side of plasma membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030154"(cell differentiation)|go:"GO:0030667"(secretory granule membrane)|go:"GO:0038023"(signaling receptor activity)|go:"GO:0042277"(peptide binding)|go:"GO:0043171"(peptide catabolic process)|go:"GO:0070006"(metalloaminopeptidase activity)|go:"GO:0070062"(extracellular exosome)|interpro:IPR001930(Peptidase M1, membrane alanine aminopeptidase)|interpro:IPR014782(Peptidase M1, membrane alanine aminopeptidase, N-terminal)|interpro:IPR024571|interpro:IPR027268|interpro:IPR034016|interpro:IPR042097|rcsb pdb:4FYQ|rcsb pdb:4FYR|rcsb pdb:4FYS|rcsb pdb:4FYT|rcsb pdb:5LHD|rcsb pdb:6ATK|rcsb pdb:6U7E|rcsb pdb:6U7F|rcsb pdb:6U7G|rcsb pdb:6XWD|rcsb pdb:7AEW|reactome:R-HSA-2022377|reactome:R-HSA-6798695|refseq:XP_005254949.1 - - - comment:"Proteins significantly enriched by immunoprecipitation with 34ED556 (T1) anti-TEX101 antibody in human sperm cells from pre-vasectomy semen samples."|figure legend:Fig. 2B, supplemental Table S6|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-spermatozoa)|taxid:9606(Homo sapiens) - 2020/03/24 2020/04/07 rogid:ZE4tXTFi7lUCcIbCL4KHzY3a6xM9606 rogid:rKOeK87j6V1zOyRYGR7v2CHuZn09606 rigid:TX1oljMyfkimcULEvhCJR/BRAW4 false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9BY14 uniprotkb:Q9BY14 intact:EBI-12549378|ensembl:ENSP00000472769|uniprotkb:Q7L5R2|uniprotkb:Q9BPY7 intact:EBI-12549378|ensembl:ENSP00000472769|uniprotkb:Q7L5R2|uniprotkb:Q9BPY7 psi-mi:tx101_human(display_long)|uniprotkb:TEX101(gene name)|psi-mi:TEX101(display_short)|uniprotkb:Cell surface receptor NYD-SP8(gene name synonym)|uniprotkb:SGRG(gene name synonym)|uniprotkb:Scleroderma-associated autoantigen(gene name synonym)|uniprotkb:Spermatogenesis-related gene protein(gene name synonym)|uniprotkb:UNQ867/PRO1884(orf name) psi-mi:tx101_human(display_long)|uniprotkb:TEX101(gene name)|psi-mi:TEX101(display_short)|uniprotkb:Cell surface receptor NYD-SP8(gene name synonym)|uniprotkb:SGRG(gene name synonym)|uniprotkb:Scleroderma-associated autoantigen(gene name synonym)|uniprotkb:Spermatogenesis-related gene protein(gene name synonym)|uniprotkb:UNQ867/PRO1884(orf name) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Schiza et al. (2018) imex:IM-28077|pubmed:30097533 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-25505396|imex:IM-28077-7 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000131126(gene)|ensembl:ENST00000598265(transcript)|go:"GO:0001669"(acrosomal vesicle)|go:"GO:0002080"(acrosomal membrane)|go:"GO:0005576"(extracellular region)|go:"GO:0005886"(plasma membrane)|go:"GO:0007339"(binding of sperm to zona pellucida)|go:"GO:0009566"(fertilization)|go:"GO:0030317"(flagellated sperm motility)|go:"GO:0044853"(plasma membrane raft)|go:"GO:0046658"(anchored component of plasma membrane)|go:"GO:1901317"(regulation of flagellated sperm motility)|interpro:IPR016054(Ly-6 antigen / uPA receptor -like)|rcsb pdb:7BPR|reactome:R-HSA-163125|refseq:NP_001123483.1|refseq:NP_113639.4 ensembl:ENSG00000131126(gene)|ensembl:ENST00000598265(transcript)|go:"GO:0001669"(acrosomal vesicle)|go:"GO:0002080"(acrosomal membrane)|go:"GO:0005576"(extracellular region)|go:"GO:0005886"(plasma membrane)|go:"GO:0007339"(binding of sperm to zona pellucida)|go:"GO:0009566"(fertilization)|go:"GO:0030317"(flagellated sperm motility)|go:"GO:0044853"(plasma membrane raft)|go:"GO:0046658"(anchored component of plasma membrane)|go:"GO:1901317"(regulation of flagellated sperm motility)|interpro:IPR016054(Ly-6 antigen / uPA receptor -like)|rcsb pdb:7BPR|reactome:R-HSA-163125|refseq:NP_001123483.1|refseq:NP_113639.4 - - - comment:"Proteins significantly enriched by immunoprecipitation with 34ED556 (T1) anti-TEX101 antibody in human sperm cells from pre-vasectomy semen samples."|figure legend:Fig. 2B, supplemental Table S6|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-spermatozoa)|taxid:9606(Homo sapiens) - 2020/03/24 2020/04/07 rogid:ZE4tXTFi7lUCcIbCL4KHzY3a6xM9606 rogid:ZE4tXTFi7lUCcIbCL4KHzY3a6xM9606 rigid:TX1oljMyfkimcULEvhCJR/BRAW4 false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9BY14 uniprotkb:P14174 intact:EBI-12549378|ensembl:ENSP00000472769|uniprotkb:Q7L5R2|uniprotkb:Q9BPY7 intact:EBI-372712|uniprotkb:A5Z1R8|uniprotkb:B2R4S3|uniprotkb:Q6FHV0|uniprotkb:Q2V4Y5|ensembl:ENSP00000215754|ensembl:ENSP00000482779 psi-mi:tx101_human(display_long)|uniprotkb:TEX101(gene name)|psi-mi:TEX101(display_short)|uniprotkb:Cell surface receptor NYD-SP8(gene name synonym)|uniprotkb:SGRG(gene name synonym)|uniprotkb:Scleroderma-associated autoantigen(gene name synonym)|uniprotkb:Spermatogenesis-related gene protein(gene name synonym)|uniprotkb:UNQ867/PRO1884(orf name) psi-mi:mif_human(display_long)|uniprotkb:MIF(gene name)|psi-mi:MIF(display_short)|uniprotkb:MMIF(gene name synonym)|uniprotkb:GLIF(gene name synonym)|uniprotkb:Phenylpyruvate tautomerase(gene name synonym)|uniprotkb:Glycosylation-inhibiting factor(gene name synonym)|uniprotkb:L-dopachrome tautomerase(gene name synonym)|uniprotkb:L-dopachrome isomerase(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Schiza et al. (2018) imex:IM-28077|pubmed:30097533 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-25505663|imex:IM-28077-9 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000131126(gene)|ensembl:ENST00000598265(transcript)|go:"GO:0001669"(acrosomal vesicle)|go:"GO:0002080"(acrosomal membrane)|go:"GO:0005576"(extracellular region)|go:"GO:0005886"(plasma membrane)|go:"GO:0007339"(binding of sperm to zona pellucida)|go:"GO:0009566"(fertilization)|go:"GO:0030317"(flagellated sperm motility)|go:"GO:0044853"(plasma membrane raft)|go:"GO:0046658"(anchored component of plasma membrane)|go:"GO:1901317"(regulation of flagellated sperm motility)|interpro:IPR016054(Ly-6 antigen / uPA receptor -like)|rcsb pdb:7BPR|reactome:R-HSA-163125|refseq:NP_001123483.1|refseq:NP_113639.4 refseq:NP_002406.1|ensembl:ENST00000215754(transcript)|ensembl:ENST00000613839(transcript)|go:"GO:0001516"(prostaglandin biosynthetic process)|go:"GO:0001819"(positive regulation of cytokine production)|go:"GO:0004167"(dopachrome isomerase activity)|go:"GO:0005125"(cytokine activity)|go:"GO:0005126"(cytokine receptor binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|ensembl:ENSG00000276701(gene)|go:"GO:0006954"(inflammatory response)|go:"GO:0007166"(cell surface receptor signaling pathway)|go:"GO:0009986"(cell surface)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0010739"(positive regulation of protein kinase A signaling)|go:"GO:0010760"(negative regulation of macrophage chemotaxis)|go:"GO:0019752"(carboxylic acid metabolic process)|go:"GO:0030336"(negative regulation of cell migration)|go:"GO:0030890"(positive regulation of B cell proliferation)|go:"GO:0031982"(vesicle)|go:"GO:0032760"(positive regulation of tumor necrosis factor production)|go:"GO:0033138"(positive regulation of peptidyl-serine phosphorylation)|go:"GO:0034774"(secretory granule lumen)|go:"GO:0042056"(chemoattractant activity)|go:"GO:0042327"(positive regulation of phosphorylation)|go:"GO:0042802"(identical protein binding)|go:"GO:0043030"(regulation of macrophage activation)|go:"GO:0043066"(negative regulation of apoptotic process)|ensembl:ENSG00000240972(gene)|go:"GO:0043518"(negative regulation of DNA damage response, signal transduction by p53 class mediator)|go:"GO:0045087"(innate immune response)|go:"GO:0048146"(positive regulation of fibroblast proliferation)|go:"GO:0050178"(phenylpyruvate tautomerase activity)|go:"GO:0050731"(positive regulation of peptidyl-tyrosine phosphorylation)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070207"(protein homotrimerization)|go:"GO:0070374"(positive regulation of ERK1 and ERK2 cascade)|go:"GO:0090344"(negative regulation of cell aging)|go:"GO:1902166"(negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator)|go:"GO:1904813"(ficolin-1-rich granule lumen)|interpro:IPR001398(Macrophage migration inhibitory factor)|interpro:IPR014347(Tautomerase)|interpro:IPR019829|mint:P14174|rcsb pdb:1CGQ|rcsb pdb:1GCZ|rcsb pdb:1GD0|rcsb pdb:1GIF|rcsb pdb:1LJT|rcsb pdb:1MIF|rcsb pdb:1P1G|rcsb pdb:2OOH|rcsb pdb:2OOW|rcsb pdb:2OOZ|rcsb pdb:3B9S|rcsb pdb:3CE4|rcsb pdb:3DJH|rcsb pdb:3DJI|rcsb pdb:3HOF|rcsb pdb:3IJG|rcsb pdb:3IJJ|rcsb pdb:3JSF|rcsb pdb:3JSG|rcsb pdb:3JTU|rcsb pdb:3L5P|rcsb pdb:3L5R|rcsb pdb:3L5S|rcsb pdb:3L5T|rcsb pdb:3L5U|rcsb pdb:3L5V|rcsb pdb:3SMB|rcsb pdb:3SMC|rcsb pdb:3U18|rcsb pdb:3WNR|rcsb pdb:3WNS|rcsb pdb:3WNT|rcsb pdb:4ETG|rcsb pdb:4EUI|rcsb pdb:4EVG|rcsb pdb:4F2K|rcsb pdb:4GRN|rcsb pdb:4GRO|rcsb pdb:4GRP|rcsb pdb:4GRQ|rcsb pdb:4GRR|rcsb pdb:4GRU|rcsb pdb:4GUM|rcsb pdb:4K9G|rcsb pdb:4OSF|rcsb pdb:4OYQ|rcsb pdb:4P01|rcsb pdb:4P0H|rcsb pdb:4PKK|rcsb pdb:4PKZ|rcsb pdb:4PLU|rcsb pdb:4TRF|rcsb pdb:4TRU|rcsb pdb:4WR8|rcsb pdb:4WRB|rcsb pdb:4XX7|rcsb pdb:4XX8|rcsb pdb:4Z15|rcsb pdb:4Z1T|rcsb pdb:4Z1U|rcsb pdb:5B4O|rcsb pdb:5BS9|rcsb pdb:5BSC|rcsb pdb:5BSI|rcsb pdb:5BSJ|rcsb pdb:5EIZ|rcsb pdb:5HVS|rcsb pdb:5HVT|rcsb pdb:5HVV|rcsb pdb:5J7P|rcsb pdb:5J7Q|rcsb pdb:5UMJ|rcsb pdb:5UMK|rcsb pdb:5UZY|rcsb pdb:5V70|rcsb pdb:5V73|rcsb pdb:5XEJ|rcsb pdb:1CA7|rcsb pdb:6B1C|rcsb pdb:6B1K|rcsb pdb:6B2C|rcsb pdb:6BG6|rcsb pdb:6BG7|rcsb pdb:6CB5|rcsb pdb:6CBF|rcsb pdb:6CBG|rcsb pdb:6FVE|rcsb pdb:6FVH|rcsb pdb:6OY8|rcsb pdb:6OYB|rcsb pdb:6OYE|rcsb pdb:6OYG|rcsb pdb:6PEG|reactome:R-HSA-202733|reactome:R-HSA-6798695|reactome:R-HSA-8950505|rcsb pdb:6CBH|dip:DIP-31137N - - - comment:"Proteins significantly enriched by immunoprecipitation with 34ED556 (T1) anti-TEX101 antibody in human seminal plasma from pre-vasectomy semen samples."|figure legend:Fig. 2C, supplemental Table S7|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-seminal _fluid)|taxid:9606(Human seminal fluid) - 2020/03/24 2020/04/07 rogid:ZE4tXTFi7lUCcIbCL4KHzY3a6xM9606 rogid:Vk+Sfaz5c59y8dKKJ4Qn+7fjwvQ9606 rigid:pks5IYYH9Nc4ZJXDIjAUAp2Xj7s false - - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q9BY14 uniprotkb:O95819 intact:EBI-12549378|ensembl:ENSP00000472769|uniprotkb:Q7L5R2|uniprotkb:Q9BPY7 intact:EBI-2511133|intact:EBI-28985706|ensembl:ENSP00000314363|uniprotkb:Q9NST7|uniprotkb:O75172|uniprotkb:E7ESS2 psi-mi:tx101_human(display_long)|uniprotkb:TEX101(gene name)|psi-mi:TEX101(display_short)|uniprotkb:Cell surface receptor NYD-SP8(gene name synonym)|uniprotkb:SGRG(gene name synonym)|uniprotkb:Scleroderma-associated autoantigen(gene name synonym)|uniprotkb:Spermatogenesis-related gene protein(gene name synonym)|uniprotkb:UNQ867/PRO1884(orf name) psi-mi:m4k4_human(display_long)|uniprotkb:MAP4K4(gene name)|psi-mi:MAP4K4(display_short)|uniprotkb:HGK(gene name synonym)|uniprotkb:KIAA0687(gene name synonym)|uniprotkb:NIK(gene name synonym)|uniprotkb:MAPK/ERK kinase kinase kinase 4(gene name synonym)|uniprotkb:HPK/GCK-like kinase HGK(gene name synonym)|uniprotkb:Nck-interacting kinase(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Schiza et al. (2018) imex:IM-28077|pubmed:30097533 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-25505663|imex:IM-28077-9 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000131126(gene)|ensembl:ENST00000598265(transcript)|go:"GO:0001669"(acrosomal vesicle)|go:"GO:0002080"(acrosomal membrane)|go:"GO:0005576"(extracellular region)|go:"GO:0005886"(plasma membrane)|go:"GO:0007339"(binding of sperm to zona pellucida)|go:"GO:0009566"(fertilization)|go:"GO:0030317"(flagellated sperm motility)|go:"GO:0044853"(plasma membrane raft)|go:"GO:0046658"(anchored component of plasma membrane)|go:"GO:1901317"(regulation of flagellated sperm motility)|interpro:IPR016054(Ly-6 antigen / uPA receptor -like)|rcsb pdb:7BPR|reactome:R-HSA-163125|refseq:NP_001123483.1|refseq:NP_113639.4 refseq:NP_663719.2|ensembl:ENST00000347699(transcript)|go:"GO:0000165"(MAPK cascade)|go:"GO:0001953"(negative regulation of cell-matrix adhesion)|go:"GO:0004111"(creatine kinase activity)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005925"(focal adhesion)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0008017"(microtubule binding)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0032014"(positive regulation of ARF protein signal transduction)|go:"GO:0032147"(activation of protein kinase activity)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043408"(regulation of MAPK cascade)|go:"GO:0043547"(positive regulation of GTPase activity)|go:"GO:0046328"(regulation of JNK cascade)|go:"GO:0048812"(neuron projection morphogenesis)|go:"GO:0051549"(positive regulation of keratinocyte migration)|go:"GO:0051894"(positive regulation of focal adhesion assembly)|go:"GO:0061179"(negative regulation of insulin secretion involved in cellular response to glucose stimulus)|go:"GO:0070571"(negative regulation of neuron projection regeneration)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:0120183"(positive regulation of focal adhesion disassembly)|interpro:IPR000719(Protein kinase, core)|interpro:IPR001180(Citron-like)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|mint:O95819|rcsb pdb:4OBO|rcsb pdb:4OBP|rcsb pdb:4OBQ|rcsb pdb:4RVT|rcsb pdb:4U3Y|rcsb pdb:4U3Z|rcsb pdb:4U40|rcsb pdb:4U41|rcsb pdb:4U42|rcsb pdb:4U43|rcsb pdb:4U44|rcsb pdb:4U45|rcsb pdb:4ZK5|rcsb pdb:4ZP5|rcsb pdb:5DI1|rcsb pdb:5J95|rcsb pdb:5W5Q|reactome:R-HSA-2559580|ensembl:ENSG00000071054(gene)|refseq:NP_001229488.1|refseq:NP_004825.3|refseq:NP_663720.1|ensembl:ENSP00000314363|ensembl:ENST00000350878|ensembl:ENSP00000343658|ensembl:ENST00000634702|ensembl:ENSP00000489579 - - - comment:"Proteins significantly enriched by immunoprecipitation with 34ED556 (T1) anti-TEX101 antibody in human seminal plasma from pre-vasectomy semen samples."|figure legend:Fig. 2C, supplemental Table S7|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-seminal _fluid)|taxid:9606(Human seminal fluid) - 2020/03/24 2020/04/07 rogid:ZE4tXTFi7lUCcIbCL4KHzY3a6xM9606 rogid:wEXGp6vM4HhwldyeQJKvEdilMpQ9606 rigid:pks5IYYH9Nc4ZJXDIjAUAp2Xj7s false - - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q9BY14 uniprotkb:P45877 intact:EBI-12549378|ensembl:ENSP00000472769|uniprotkb:Q7L5R2|uniprotkb:Q9BPY7 intact:EBI-953909|ensembl:ENSP00000303057|uniprotkb:A4LBB5 psi-mi:tx101_human(display_long)|uniprotkb:TEX101(gene name)|psi-mi:TEX101(display_short)|uniprotkb:Cell surface receptor NYD-SP8(gene name synonym)|uniprotkb:SGRG(gene name synonym)|uniprotkb:Scleroderma-associated autoantigen(gene name synonym)|uniprotkb:Spermatogenesis-related gene protein(gene name synonym)|uniprotkb:UNQ867/PRO1884(orf name) psi-mi:ppic_human(display_long)|uniprotkb:Cyclophilin C(gene name synonym)|uniprotkb:PPIC(gene name)|psi-mi:PPIC(display_short)|uniprotkb:CYPC(gene name synonym)|uniprotkb:Rotamase C(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Schiza et al. (2018) imex:IM-28077|pubmed:30097533 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-25505663|imex:IM-28077-9 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000131126(gene)|ensembl:ENST00000598265(transcript)|go:"GO:0001669"(acrosomal vesicle)|go:"GO:0002080"(acrosomal membrane)|go:"GO:0005576"(extracellular region)|go:"GO:0005886"(plasma membrane)|go:"GO:0007339"(binding of sperm to zona pellucida)|go:"GO:0009566"(fertilization)|go:"GO:0030317"(flagellated sperm motility)|go:"GO:0044853"(plasma membrane raft)|go:"GO:0046658"(anchored component of plasma membrane)|go:"GO:1901317"(regulation of flagellated sperm motility)|interpro:IPR016054(Ly-6 antigen / uPA receptor -like)|rcsb pdb:7BPR|reactome:R-HSA-163125|refseq:NP_001123483.1|refseq:NP_113639.4 ensembl:ENSG00000168938(gene)|ensembl:ENST00000306442(transcript)|go:"GO:0000413"(protein peptidyl-prolyl isomerization)|go:"GO:0003755"(peptidyl-prolyl cis-trans isomerase activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0006457"(protein folding)|go:"GO:0016018"(cyclosporin A binding)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0070062"(extracellular exosome)|interpro:IPR002130(Peptidyl-prolyl cis-trans isomerase, cyclophilin-type)|interpro:IPR020892|interpro:IPR029000|rcsb pdb:2ESL|refseq:NP_000934.1 - - - comment:"Proteins significantly enriched by immunoprecipitation with 34ED556 (T1) anti-TEX101 antibody in human seminal plasma from pre-vasectomy semen samples."|figure legend:Fig. 2C, supplemental Table S7|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-seminal _fluid)|taxid:9606(Human seminal fluid) - 2020/03/24 2020/04/07 rogid:ZE4tXTFi7lUCcIbCL4KHzY3a6xM9606 rogid:/VJ1F3I3czCiuKiWoMs2N3NQfTc9606 rigid:pks5IYYH9Nc4ZJXDIjAUAp2Xj7s false - - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q9BY14 uniprotkb:P09467 intact:EBI-12549378|ensembl:ENSP00000472769|uniprotkb:Q7L5R2|uniprotkb:Q9BPY7 intact:EBI-712740|ensembl:ENSP00000364475|ensembl:ENSP00000408025|uniprotkb:O75571|uniprotkb:Q53F94|uniprotkb:Q96E46 psi-mi:tx101_human(display_long)|uniprotkb:TEX101(gene name)|psi-mi:TEX101(display_short)|uniprotkb:Cell surface receptor NYD-SP8(gene name synonym)|uniprotkb:SGRG(gene name synonym)|uniprotkb:Scleroderma-associated autoantigen(gene name synonym)|uniprotkb:Spermatogenesis-related gene protein(gene name synonym)|uniprotkb:UNQ867/PRO1884(orf name) psi-mi:f16p1_human(display_long)|uniprotkb:D-fructose-1,6-bisphosphate 1-phosphohydrolase 1(gene name synonym)|uniprotkb:FBP1(gene name)|psi-mi:FBP1(display_short)|uniprotkb:FBP(gene name synonym)|uniprotkb:Liver FBPase(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Schiza et al. (2018) imex:IM-28077|pubmed:30097533 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-25505663|imex:IM-28077-9 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000131126(gene)|ensembl:ENST00000598265(transcript)|go:"GO:0001669"(acrosomal vesicle)|go:"GO:0002080"(acrosomal membrane)|go:"GO:0005576"(extracellular region)|go:"GO:0005886"(plasma membrane)|go:"GO:0007339"(binding of sperm to zona pellucida)|go:"GO:0009566"(fertilization)|go:"GO:0030317"(flagellated sperm motility)|go:"GO:0044853"(plasma membrane raft)|go:"GO:0046658"(anchored component of plasma membrane)|go:"GO:1901317"(regulation of flagellated sperm motility)|interpro:IPR016054(Ly-6 antigen / uPA receptor -like)|rcsb pdb:7BPR|reactome:R-HSA-163125|refseq:NP_001123483.1|refseq:NP_113639.4 ensembl:ENST00000375326(transcript)|ensembl:ENST00000415431(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005986"(sucrose biosynthetic process)|go:"GO:0006000"(fructose metabolic process)|go:"GO:0006002"(fructose 6-phosphate metabolic process)|go:"GO:0006094"(gluconeogenesis)|go:"GO:0006111"(regulation of gluconeogenesis)|go:"GO:0016208"(AMP binding)|go:"GO:0016311"(dephosphorylation)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0030388"(fructose 1,6-bisphosphate metabolic process)|go:"GO:0035690"|go:"GO:0042132"(fructose 1,6-bisphosphate 1-phosphatase activity)|go:"GO:0042802"(identical protein binding)|go:"GO:0045820"(negative regulation of glycolytic process)|go:"GO:0046580"(negative regulation of Ras protein signal transduction)|go:"GO:0046872"(metal ion binding)|go:"GO:0048029"(monosaccharide binding)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071286"(cellular response to magnesium ion)|interpro:IPR000146(Inositol phosphatase/fructose-1,6-bisphosphatase)|interpro:IPR020548|interpro:IPR028343|interpro:IPR033391|interpro:IPR044015|mint:P09467|rcsb pdb:1FTA|rcsb pdb:2FHY|rcsb pdb:2FIE|rcsb pdb:2FIX|rcsb pdb:2JJK|rcsb pdb:2VT5|rcsb pdb:2WBB|rcsb pdb:2WBD|rcsb pdb:2Y5K|rcsb pdb:2Y5L|rcsb pdb:3A29|rcsb pdb:3KBZ|rcsb pdb:3KC0|ensembl:ENSG00000165140(gene)|rcsb pdb:3KC1|rcsb pdb:4MJO|rcsb pdb:5LDZ|rcsb pdb:5PZR|rcsb pdb:5PZS|rcsb pdb:5PZT|rcsb pdb:5PZU|rcsb pdb:5PZV|rcsb pdb:5PZW|rcsb pdb:5PZX|rcsb pdb:5PZY|rcsb pdb:5PZZ|rcsb pdb:5Q00|rcsb pdb:5Q01|rcsb pdb:5Q02|rcsb pdb:5Q03|rcsb pdb:5Q04|rcsb pdb:5Q05|rcsb pdb:5Q06|rcsb pdb:5Q07|rcsb pdb:5Q08|rcsb pdb:5Q09|rcsb pdb:5PZQ|rcsb pdb:5Q0A|rcsb pdb:5Q0B|rcsb pdb:6LS5|rcsb pdb:6LW2|rcsb pdb:7C9Q|rcsb pdb:7CVN|reactome:R-HSA-70263|refseq:NP_000498.2|refseq:NP_001121100.1|dip:DIP-46677N - - - comment:"Proteins significantly enriched by immunoprecipitation with 34ED556 (T1) anti-TEX101 antibody in human seminal plasma from pre-vasectomy semen samples."|figure legend:Fig. 2C, supplemental Table S7|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-seminal _fluid)|taxid:9606(Human seminal fluid) - 2020/03/24 2020/04/07 rogid:ZE4tXTFi7lUCcIbCL4KHzY3a6xM9606 rogid:DnrtyrU5WL/7ut1qWv7LndveJT89606 rigid:pks5IYYH9Nc4ZJXDIjAUAp2Xj7s false - - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q9BY14 uniprotkb:Q06323 intact:EBI-12549378|ensembl:ENSP00000472769|uniprotkb:Q7L5R2|uniprotkb:Q9BPY7 intact:EBI-712149|uniprotkb:H0YNE3|ensembl:ENSP00000206451|ensembl:ENSP00000495095|uniprotkb:Q9UEF4|uniprotkb:Q6IBM2|uniprotkb:A6NJG9 psi-mi:tx101_human(display_long)|uniprotkb:TEX101(gene name)|psi-mi:TEX101(display_short)|uniprotkb:Cell surface receptor NYD-SP8(gene name synonym)|uniprotkb:SGRG(gene name synonym)|uniprotkb:Scleroderma-associated autoantigen(gene name synonym)|uniprotkb:Spermatogenesis-related gene protein(gene name synonym)|uniprotkb:UNQ867/PRO1884(orf name) psi-mi:psme1_human(display_long)|uniprotkb:Proteasome activator 28 subunit alpha(gene name synonym)|uniprotkb:Activator of multicatalytic protease subunit 1(gene name synonym)|uniprotkb:11S regulator complex subunit alpha(gene name synonym)|uniprotkb:Interferon gamma up-regulated I-5111 protein(gene name synonym)|uniprotkb:PSME1(gene name)|psi-mi:PSME1(display_short)|uniprotkb:IFI5111(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Schiza et al. (2018) imex:IM-28077|pubmed:30097533 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-25505663|imex:IM-28077-9 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000131126(gene)|ensembl:ENST00000598265(transcript)|go:"GO:0001669"(acrosomal vesicle)|go:"GO:0002080"(acrosomal membrane)|go:"GO:0005576"(extracellular region)|go:"GO:0005886"(plasma membrane)|go:"GO:0007339"(binding of sperm to zona pellucida)|go:"GO:0009566"(fertilization)|go:"GO:0030317"(flagellated sperm motility)|go:"GO:0044853"(plasma membrane raft)|go:"GO:0046658"(anchored component of plasma membrane)|go:"GO:1901317"(regulation of flagellated sperm motility)|interpro:IPR016054(Ly-6 antigen / uPA receptor -like)|rcsb pdb:7BPR|reactome:R-HSA-163125|refseq:NP_001123483.1|refseq:NP_113639.4 reactome:R-HSA-5678895|reactome:R-HSA-8941858|reactome:R-HSA-8948751|reactome:R-HSA-5687128|reactome:R-HSA-8951664|reactome:R-HSA-9010553|reactome:R-HSA-9020702|reactome:R-HSA-5689603|reactome:R-HSA-5689880|reactome:R-HSA-68827|reactome:R-HSA-68949|reactome:R-HSA-69017|reactome:R-HSA-69481|reactome:R-HSA-9604323|reactome:R-HSA-983168|reactome:R-HSA-69601|reactome:R-HSA-75815|reactome:R-HSA-8852276|reactome:R-HSA-8854050|reactome:R-HSA-8932339|reactome:R-HSA-8939236|reactome:R-HSA-8939902|ensembl:ENSG00000092010(gene)|ensembl:ENSG00000284916(gene)|ensembl:ENST00000206451(transcript)|ensembl:ENST00000645537(transcript)|go:"GO:0000502"(proteasome complex)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0008537"(proteasome activator complex)|go:"GO:0010950"(positive regulation of endopeptidase activity)|go:"GO:0019884"(antigen processing and presentation of exogenous antigen)|go:"GO:0061133"(endopeptidase activator activity)|go:"GO:0061136"(regulation of proteasomal protein catabolic process)|go:"GO:0070062"(extracellular exosome)|go:"GO:2000045"(regulation of G1/S transition of mitotic cell cycle)|interpro:IPR003185(Proteasome activator pa28, REG alpha subunit)|interpro:IPR003186(Proteasome activator pa28, REG beta subunit)|interpro:IPR009077(Proteasome activator pa28, REG alpha/beta subunit)|interpro:IPR036252|interpro:IPR036996|interpro:IPR036997|mint:Q06323|rcsb pdb:1AVO|rcsb pdb:7DR6|rcsb pdb:7DRW|reactome:R-HSA-1169091|reactome:R-HSA-1234176|reactome:R-HSA-1236974|reactome:R-HSA-1236978|reactome:R-HSA-174084|reactome:R-HSA-174113|reactome:R-HSA-174154|reactome:R-HSA-174178|reactome:R-HSA-174184|reactome:R-HSA-180534|reactome:R-HSA-180585|reactome:R-HSA-187577|reactome:R-HSA-195253|reactome:R-HSA-202424|reactome:R-HSA-211733|reactome:R-HSA-2467813|reactome:R-HSA-2871837|reactome:R-HSA-349425|reactome:R-HSA-350562|reactome:R-HSA-382556|reactome:R-HSA-450408|reactome:R-HSA-4608870|reactome:R-HSA-4641257|reactome:R-HSA-4641258|reactome:R-HSA-5358346|reactome:R-HSA-5362768|reactome:R-HSA-5607761|reactome:R-HSA-5607764|reactome:R-HSA-5610780|reactome:R-HSA-5610783|reactome:R-HSA-5610785|reactome:R-HSA-5632684|reactome:R-HSA-5658442|reactome:R-HSA-5668541|reactome:R-HSA-5676590|refseq:NP_006254.1|refseq:NP_001268457.1 - - - comment:"Proteins significantly enriched by immunoprecipitation with 34ED556 (T1) anti-TEX101 antibody in human seminal plasma from pre-vasectomy semen samples."|figure legend:Fig. 2C, supplemental Table S7|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-seminal _fluid)|taxid:9606(Human seminal fluid) - 2020/03/24 2020/04/07 rogid:ZE4tXTFi7lUCcIbCL4KHzY3a6xM9606 rogid:kyTjI3VP2S7Bvwq4R0pJudnlOC09606 rigid:pks5IYYH9Nc4ZJXDIjAUAp2Xj7s false - - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q9BY14 uniprotkb:Q9HCL0 intact:EBI-12549378|ensembl:ENSP00000472769|uniprotkb:Q7L5R2|uniprotkb:Q9BPY7 intact:EBI-2949740|intact:EBI-28975745|uniprotkb:A8K7K3|uniprotkb:B7ZKT1|uniprotkb:Q52LS2|ensembl:ENSP00000355082 psi-mi:tx101_human(display_long)|uniprotkb:TEX101(gene name)|psi-mi:TEX101(display_short)|uniprotkb:Cell surface receptor NYD-SP8(gene name synonym)|uniprotkb:SGRG(gene name synonym)|uniprotkb:Scleroderma-associated autoantigen(gene name synonym)|uniprotkb:Spermatogenesis-related gene protein(gene name synonym)|uniprotkb:UNQ867/PRO1884(orf name) psi-mi:pcd18_human(display_long)|uniprotkb:PCDH18(gene name)|psi-mi:PCDH18(display_short)|uniprotkb:KIAA1562(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Schiza et al. (2018) imex:IM-28077|pubmed:30097533 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-25505663|imex:IM-28077-9 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000131126(gene)|ensembl:ENST00000598265(transcript)|go:"GO:0001669"(acrosomal vesicle)|go:"GO:0002080"(acrosomal membrane)|go:"GO:0005576"(extracellular region)|go:"GO:0005886"(plasma membrane)|go:"GO:0007339"(binding of sperm to zona pellucida)|go:"GO:0009566"(fertilization)|go:"GO:0030317"(flagellated sperm motility)|go:"GO:0044853"(plasma membrane raft)|go:"GO:0046658"(anchored component of plasma membrane)|go:"GO:1901317"(regulation of flagellated sperm motility)|interpro:IPR016054(Ly-6 antigen / uPA receptor -like)|rcsb pdb:7BPR|reactome:R-HSA-163125|refseq:NP_001123483.1|refseq:NP_113639.4 ensembl:ENSP00000355082|ensembl:ENST00000412923|ensembl:ENSP00000390688|refseq:NP_061908.1|refseq:NP_001287757.1|ensembl:ENSG00000189184(gene)|ensembl:ENST00000344876(transcript)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0007155"(cell adhesion)|go:"GO:0007156"(homophilic cell adhesion via plasma membrane adhesion molecules)|go:"GO:0007420"(brain development)|interpro:IPR002126(Cadherin)|interpro:IPR013164(Cadherin, N-terminal)|interpro:IPR015919(Cadherin-like)|interpro:IPR020894|interpro:IPR030714|rcsb pdb:6VFR - - - comment:"Proteins significantly enriched by immunoprecipitation with 34ED556 (T1) anti-TEX101 antibody in human seminal plasma from pre-vasectomy semen samples."|figure legend:Fig. 2C, supplemental Table S7|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-seminal _fluid)|taxid:9606(Human seminal fluid) - 2020/03/24 2020/04/07 rogid:ZE4tXTFi7lUCcIbCL4KHzY3a6xM9606 rogid:p9iHqKNdtYEFxwF/vu8Ssu/o1X09606 rigid:pks5IYYH9Nc4ZJXDIjAUAp2Xj7s false - - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q9BY14 uniprotkb:P35579 intact:EBI-12549378|ensembl:ENSP00000472769|uniprotkb:Q7L5R2|uniprotkb:Q9BPY7 intact:EBI-350338|uniprotkb:O60805|ensembl:ENSP00000216181|uniprotkb:Q86T83|intact:EBI-1054343|uniprotkb:A8K6E4|uniprotkb:Q60FE2 psi-mi:tx101_human(display_long)|uniprotkb:TEX101(gene name)|psi-mi:TEX101(display_short)|uniprotkb:Cell surface receptor NYD-SP8(gene name synonym)|uniprotkb:SGRG(gene name synonym)|uniprotkb:Scleroderma-associated autoantigen(gene name synonym)|uniprotkb:Spermatogenesis-related gene protein(gene name synonym)|uniprotkb:UNQ867/PRO1884(orf name) psi-mi:myh9_human(display_long)|uniprotkb:MYH9(gene name)|psi-mi:MYH9(display_short)|uniprotkb:Myosin heavy chain 9(gene name synonym)|uniprotkb:Myosin heavy chain, non-muscle IIa(gene name synonym)|uniprotkb:Non-muscle myosin heavy chain IIa(gene name synonym)|uniprotkb:Cellular myosin heavy chain, type A(gene name synonym)|uniprotkb:Non-muscle myosin heavy chain A(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Schiza et al. (2018) imex:IM-28077|pubmed:30097533 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-25505663|imex:IM-28077-9 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000131126(gene)|ensembl:ENST00000598265(transcript)|go:"GO:0001669"(acrosomal vesicle)|go:"GO:0002080"(acrosomal membrane)|go:"GO:0005576"(extracellular region)|go:"GO:0005886"(plasma membrane)|go:"GO:0007339"(binding of sperm to zona pellucida)|go:"GO:0009566"(fertilization)|go:"GO:0030317"(flagellated sperm motility)|go:"GO:0044853"(plasma membrane raft)|go:"GO:0046658"(anchored component of plasma membrane)|go:"GO:1901317"(regulation of flagellated sperm motility)|interpro:IPR016054(Ly-6 antigen / uPA receptor -like)|rcsb pdb:7BPR|reactome:R-HSA-163125|refseq:NP_001123483.1|refseq:NP_113639.4 refseq:NP_002464.1|ensembl:ENSG00000100345(gene)|ensembl:ENST00000216181(transcript)|go:"GO:0000146"(microfilament motor activity)|go:"GO:0000212"(meiotic spindle organization)|go:"GO:0001525"(angiogenesis)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0001725"(stress fiber)|go:"GO:0001726"(ruffle)|go:"GO:0001768"(establishment of T cell polarity)|go:"GO:0001772"(immunological synapse)|go:"GO:0001778"(plasma membrane repair)|go:"GO:0001931"(uropod)|go:"GO:0003723"(RNA binding)|go:"GO:0003774"(cytoskeletal motor activity)|go:"GO:0003779"(actin binding)|go:"GO:0005178"(integrin binding)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005819"(spindle)|go:"GO:0005826"(actomyosin contractile ring)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005903"(brush border)|go:"GO:0005912"(adherens junction)|go:"GO:0005925"(focal adhesion)|go:"GO:0006509"(membrane protein ectodomain proteolysis)|go:"GO:0006911"(phagocytosis, engulfment)|go:"GO:0007229"(integrin-mediated signaling pathway)|go:"GO:0007520"(myoblast fusion)|go:"GO:0008360"(regulation of cell shape)|go:"GO:0009898"(cytoplasmic side of plasma membrane)|go:"GO:0015031"(protein transport)|refseq:XP_011528499.1|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0016020"(membrane)|go:"GO:0016460"(myosin II complex)|go:"GO:0016887"(ATP hydrolysis activity)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030048"(actin filament-based movement)|go:"GO:0030220"(platelet formation)|go:"GO:0030224"(monocyte differentiation)|go:"GO:0031032"(actomyosin structure organization)|go:"GO:0031252"(cell leading edge)|go:"GO:0031532"(actin cytoskeleton reorganization)|go:"GO:0031594"(neuromuscular junction)|go:"GO:0032154"(cleavage furrow)|go:"GO:0032418"(lysosome localization)|go:"GO:0032506"(cytokinetic process)|go:"GO:0032796"(uropod organization)|go:"GO:0032991"(protein-containing complex)|go:"GO:0042641"(actomyosin)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043495"(protein-membrane adaptor activity)|go:"GO:0043531"(ADP binding)|go:"GO:0043534"(blood vessel endothelial cell migration)|go:"GO:0045055"(regulated exocytosis)|go:"GO:0045296"(cadherin binding)|go:"GO:0050900"(leukocyte migration)|go:"GO:0051015"(actin filament binding)|go:"GO:0051295"(establishment of meiotic spindle localization)|go:"GO:0060471"(cortical granule exocytosis)|go:"GO:0060473"(cortical granule)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070527"(platelet aggregation)|go:"GO:0097513"(myosin II filament)|go:"GO:1903919"(negative regulation of actin filament severing)|rcsb pdb:4CFR|rcsb pdb:4ETO|reactome:R-HSA-1445148|reactome:R-HSA-2029482|reactome:R-HSA-3928663|reactome:R-HSA-416572|reactome:R-HSA-5625740|reactome:R-HSA-5625900|reactome:R-HSA-5627117|reactome:R-HSA-5627123|reactome:R-HSA-9662360|reactome:R-HSA-9662361|reactome:R-HSA-9662834|reactome:R-HSA-9664422|go:"GO:1903923"(positive regulation of protein processing in phagocytic vesicle)|go:"GO:1905684"(regulation of plasma membrane repair)|interpro:IPR000048(IQ calmodulin-binding region)|interpro:IPR001609(Myosin head, motor region)|interpro:IPR002928(Myosin tail)|interpro:IPR004009(Myosin, N-terminal, SH3-like)|interpro:IPR008989(Myosin S1 fragment, N-terminal)|interpro:IPR027417|interpro:IPR036305|interpro:IPR036961|mint:P35579|rcsb pdb:2LNK|rcsb pdb:3ZWH|rcsb pdb:4CFQ|refseq:XP_016884292.1|refseq:XP_016884293.1|refseq:XP_016884294.1|refseq:XP_016884295.1|dip:DIP-33103N - - - comment:"Proteins significantly enriched by immunoprecipitation with 34ED556 (T1) anti-TEX101 antibody in human seminal plasma from pre-vasectomy semen samples."|figure legend:Fig. 2C, supplemental Table S7|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-seminal _fluid)|taxid:9606(Human seminal fluid) - 2020/03/24 2020/04/07 rogid:ZE4tXTFi7lUCcIbCL4KHzY3a6xM9606 rogid:fSOtpFpr8PSnAG5UdAr/khwkzJs9606 rigid:pks5IYYH9Nc4ZJXDIjAUAp2Xj7s false - - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q9BY14 uniprotkb:Q8WXA2 intact:EBI-12549378|ensembl:ENSP00000472769|uniprotkb:Q7L5R2|uniprotkb:Q9BPY7 intact:EBI-10277790|uniprotkb:Q3KNX2|ensembl:ENSP00000307164 psi-mi:tx101_human(display_long)|uniprotkb:TEX101(gene name)|psi-mi:TEX101(display_short)|uniprotkb:Cell surface receptor NYD-SP8(gene name synonym)|uniprotkb:SGRG(gene name synonym)|uniprotkb:Scleroderma-associated autoantigen(gene name synonym)|uniprotkb:Spermatogenesis-related gene protein(gene name synonym)|uniprotkb:UNQ867/PRO1884(orf name) psi-mi:pate1_human(display_long)|uniprotkb:PATE1(gene name)|psi-mi:PATE1(display_short)|uniprotkb:PATE(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Schiza et al. (2018) imex:IM-28077|pubmed:30097533 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-25505663|imex:IM-28077-9 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000131126(gene)|ensembl:ENST00000598265(transcript)|go:"GO:0001669"(acrosomal vesicle)|go:"GO:0002080"(acrosomal membrane)|go:"GO:0005576"(extracellular region)|go:"GO:0005886"(plasma membrane)|go:"GO:0007339"(binding of sperm to zona pellucida)|go:"GO:0009566"(fertilization)|go:"GO:0030317"(flagellated sperm motility)|go:"GO:0044853"(plasma membrane raft)|go:"GO:0046658"(anchored component of plasma membrane)|go:"GO:1901317"(regulation of flagellated sperm motility)|interpro:IPR016054(Ly-6 antigen / uPA receptor -like)|rcsb pdb:7BPR|reactome:R-HSA-163125|refseq:NP_001123483.1|refseq:NP_113639.4 refseq:NP_612151.1|ensembl:ENSG00000171053(gene)|ensembl:ENST00000305738(transcript)|go:"GO:0005576"(extracellular region)|go:"GO:0030548"(acetylcholine receptor regulator activity)|go:"GO:0099601"(regulation of neurotransmitter receptor activity) - - - comment:"Proteins significantly enriched by immunoprecipitation with 34ED556 (T1) anti-TEX101 antibody in human seminal plasma from pre-vasectomy semen samples."|figure legend:Fig. 2C, supplemental Table S7|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-seminal _fluid)|taxid:9606(Human seminal fluid) - 2020/03/24 2020/04/07 rogid:ZE4tXTFi7lUCcIbCL4KHzY3a6xM9606 rogid:PqX1ZIsi9G+Qp9KjoukpilkDcJo9606 rigid:pks5IYYH9Nc4ZJXDIjAUAp2Xj7s false - - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q9BY14 uniprotkb:Q14507 intact:EBI-12549378|ensembl:ENSP00000472769|uniprotkb:Q7L5R2|uniprotkb:Q9BPY7 intact:EBI-17953459|uniprotkb:Q4KN33|ensembl:ENSP00000315098 psi-mi:tx101_human(display_long)|uniprotkb:TEX101(gene name)|psi-mi:TEX101(display_short)|uniprotkb:Cell surface receptor NYD-SP8(gene name synonym)|uniprotkb:SGRG(gene name synonym)|uniprotkb:Scleroderma-associated autoantigen(gene name synonym)|uniprotkb:Spermatogenesis-related gene protein(gene name synonym)|uniprotkb:UNQ867/PRO1884(orf name) psi-mi:ep3a_human(display_long)|uniprotkb:Human epididymis-specific protein 3-alpha(gene name synonym)|uniprotkb:EDDM3A(gene name)|psi-mi:EDDM3A(display_short)|uniprotkb:FAM12A(gene name synonym)|uniprotkb:HE3A(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Schiza et al. (2018) imex:IM-28077|pubmed:30097533 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-25505663|imex:IM-28077-9 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000131126(gene)|ensembl:ENST00000598265(transcript)|go:"GO:0001669"(acrosomal vesicle)|go:"GO:0002080"(acrosomal membrane)|go:"GO:0005576"(extracellular region)|go:"GO:0005886"(plasma membrane)|go:"GO:0007339"(binding of sperm to zona pellucida)|go:"GO:0009566"(fertilization)|go:"GO:0030317"(flagellated sperm motility)|go:"GO:0044853"(plasma membrane raft)|go:"GO:0046658"(anchored component of plasma membrane)|go:"GO:1901317"(regulation of flagellated sperm motility)|interpro:IPR016054(Ly-6 antigen / uPA receptor -like)|rcsb pdb:7BPR|reactome:R-HSA-163125|refseq:NP_001123483.1|refseq:NP_113639.4 refseq:NP_006674.2|refseq:XP_016876423.1|ensembl:ENSG00000181562(gene)|ensembl:ENST00000326842(transcript)|go:"GO:0005615"(extracellular space)|go:"GO:0007321"(sperm displacement)|interpro:IPR023412|interpro:IPR029747|interpro:IPR036816|interpro:IPR042402 - - - comment:"Proteins significantly enriched by immunoprecipitation with 34ED556 (T1) anti-TEX101 antibody in human seminal plasma from pre-vasectomy semen samples."|figure legend:Fig. 2C, supplemental Table S7|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-seminal _fluid)|taxid:9606(Human seminal fluid) - 2020/03/24 2020/04/07 rogid:ZE4tXTFi7lUCcIbCL4KHzY3a6xM9606 rogid:dS6wneFQJt6UQHJswqIrwfqp0o89606 rigid:pks5IYYH9Nc4ZJXDIjAUAp2Xj7s false - - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q9BY14 uniprotkb:P56851 intact:EBI-12549378|ensembl:ENSP00000472769|uniprotkb:Q7L5R2|uniprotkb:Q9BPY7 intact:EBI-10215665|uniprotkb:A0PK89|ensembl:ENSP00000314810 psi-mi:tx101_human(display_long)|uniprotkb:TEX101(gene name)|psi-mi:TEX101(display_short)|uniprotkb:Cell surface receptor NYD-SP8(gene name synonym)|uniprotkb:SGRG(gene name synonym)|uniprotkb:Scleroderma-associated autoantigen(gene name synonym)|uniprotkb:Spermatogenesis-related gene protein(gene name synonym)|uniprotkb:UNQ867/PRO1884(orf name) psi-mi:ep3b_human(display_long)|uniprotkb:EDDM3B(gene name)|psi-mi:EDDM3B(display_short)|uniprotkb:FAM12B(gene name synonym)|uniprotkb:HE3B(gene name synonym)|uniprotkb:Human epididymis-specific protein 3-beta(gene name synonym)|uniprotkb:UNQ6412/PRO21187(orf name) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Schiza et al. (2018) imex:IM-28077|pubmed:30097533 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-25505663|imex:IM-28077-9 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000131126(gene)|ensembl:ENST00000598265(transcript)|go:"GO:0001669"(acrosomal vesicle)|go:"GO:0002080"(acrosomal membrane)|go:"GO:0005576"(extracellular region)|go:"GO:0005886"(plasma membrane)|go:"GO:0007339"(binding of sperm to zona pellucida)|go:"GO:0009566"(fertilization)|go:"GO:0030317"(flagellated sperm motility)|go:"GO:0044853"(plasma membrane raft)|go:"GO:0046658"(anchored component of plasma membrane)|go:"GO:1901317"(regulation of flagellated sperm motility)|interpro:IPR016054(Ly-6 antigen / uPA receptor -like)|rcsb pdb:7BPR|reactome:R-HSA-163125|refseq:NP_001123483.1|refseq:NP_113639.4 refseq:NP_071755.1|ensembl:ENSG00000181552(gene)|ensembl:ENST00000326783(transcript)|go:"GO:0005576"(extracellular region)|interpro:IPR023412|interpro:IPR036816|interpro:IPR042402 - - - comment:"Proteins significantly enriched by immunoprecipitation with 34ED556 (T1) anti-TEX101 antibody in human seminal plasma from pre-vasectomy semen samples."|figure legend:Fig. 2C, supplemental Table S7|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-seminal _fluid)|taxid:9606(Human seminal fluid) - 2020/03/24 2020/04/07 rogid:ZE4tXTFi7lUCcIbCL4KHzY3a6xM9606 rogid:zA7UXQnKFTy2xdYB/VxX5xDo1Uo9606 rigid:pks5IYYH9Nc4ZJXDIjAUAp2Xj7s false - - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q9BY14 uniprotkb:P62805 intact:EBI-12549378|ensembl:ENSP00000472769|uniprotkb:Q7L5R2|uniprotkb:Q9BPY7 intact:EBI-302023|ensembl:ENSP00000244537|ensembl:ENSP00000347168|ensembl:ENSP00000350767|ensembl:ENSP00000366974|ensembl:ENSP00000366956|ensembl:ENSP00000462667|ensembl:ENSP00000367034|ensembl:ENSP00000478519|ensembl:ENSP00000478786|ensembl:ENSP00000443017|ensembl:ENSP00000462355|ensembl:ENSP00000479106|ensembl:ENSP00000479461|uniprotkb:A2VCL0|uniprotkb:P02304|uniprotkb:P02305|uniprotkb:Q6DRA9|uniprotkb:Q6FGB8|uniprotkb:Q6NWP7|ensembl:ENSP00000479794|ensembl:ENSP00000480960|ensembl:ENSP00000481343|ensembl:ENSP00000481486|ensembl:ENSP00000481507|ensembl:ENSP00000482412|ensembl:ENSP00000484789|ensembl:ENSP00000489319|ensembl:ENSP00000489567 psi-mi:tx101_human(display_long)|uniprotkb:TEX101(gene name)|psi-mi:TEX101(display_short)|uniprotkb:Cell surface receptor NYD-SP8(gene name synonym)|uniprotkb:SGRG(gene name synonym)|uniprotkb:Scleroderma-associated autoantigen(gene name synonym)|uniprotkb:Spermatogenesis-related gene protein(gene name synonym)|uniprotkb:UNQ867/PRO1884(orf name) psi-mi:h4_human(display_long)|uniprotkb:H4-16(gene name)|psi-mi:H4-16(display_short)|uniprotkb:H4C1(gene name)|psi-mi:H4C1(display_short)|uniprotkb:H4C11(gene name)|psi-mi:H4C11(display_short)|uniprotkb:H4C12(gene name)|psi-mi:H4C12(display_short)|uniprotkb:H4C13(gene name)|psi-mi:H4C13(display_short)|uniprotkb:H4C14(gene name)|psi-mi:H4C14(display_short)|uniprotkb:H4C15(gene name)|psi-mi:H4C15(display_short)|uniprotkb:H4C2(gene name)|psi-mi:H4C2(display_short)|uniprotkb:H4C3(gene name)|psi-mi:H4C3(display_short)|uniprotkb:H4C4(gene name)|psi-mi:H4C4(display_short)|uniprotkb:H4C5(gene name)|psi-mi:H4C5(display_short)|uniprotkb:H4C6(gene name)|psi-mi:H4C6(display_short)|uniprotkb:H4C8(gene name)|psi-mi:H4C8(display_short)|uniprotkb:H4C9(gene name)|psi-mi:H4C9(display_short)|uniprotkb:H4/A(gene name synonym)|uniprotkb:H4/B(gene name synonym)|uniprotkb:H4/C(gene name synonym)|uniprotkb:H4/D(gene name synonym)|uniprotkb:H4/E(gene name synonym)|uniprotkb:H4/G(gene name synonym)|uniprotkb:H4/H(gene name synonym)|uniprotkb:H4/I(gene name synonym)|uniprotkb:H4/J(gene name synonym)|uniprotkb:H4/K(gene name synonym)|uniprotkb:H4/M(gene name synonym)|uniprotkb:H4/N(gene name synonym)|uniprotkb:H4/O(gene name synonym)|uniprotkb:H4F2(gene name synonym)|uniprotkb:H4FA(gene name synonym)|uniprotkb:H4FB(gene name synonym)|uniprotkb:H4FC(gene name synonym)|uniprotkb:H4FD(gene name synonym)|uniprotkb:H4FE(gene name synonym)|uniprotkb:H4FG(gene name synonym)|uniprotkb:H4FH(gene name synonym)|uniprotkb:H4FI(gene name synonym)|uniprotkb:H4FJ(gene name synonym)|uniprotkb:H4FK(gene name synonym)|uniprotkb:H4FM(gene name synonym)|uniprotkb:H4FN(gene name synonym)|uniprotkb:H4FO(gene name synonym)|uniprotkb:HIST1H4A(gene name synonym)|uniprotkb:HIST1H4B(gene name synonym)|uniprotkb:HIST1H4C(gene name synonym)|uniprotkb:HIST1H4D(gene name synonym)|uniprotkb:HIST1H4E(gene name synonym)|uniprotkb:HIST1H4F(gene name synonym)|uniprotkb:HIST1H4H(gene name synonym)|uniprotkb:HIST1H4I(gene name synonym)|uniprotkb:HIST1H4J(gene name synonym)|uniprotkb:HIST1H4K(gene name synonym)|uniprotkb:HIST1H4L(gene name synonym)|uniprotkb:HIST2H4(gene name synonym)|uniprotkb:HIST2H4A(gene name synonym)|uniprotkb:HIST2H4B(gene name synonym)|uniprotkb:HIST4H4(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Schiza et al. (2018) imex:IM-28077|pubmed:30097533 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-25505663|imex:IM-28077-9 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000131126(gene)|ensembl:ENST00000598265(transcript)|go:"GO:0001669"(acrosomal vesicle)|go:"GO:0002080"(acrosomal membrane)|go:"GO:0005576"(extracellular region)|go:"GO:0005886"(plasma membrane)|go:"GO:0007339"(binding of sperm to zona pellucida)|go:"GO:0009566"(fertilization)|go:"GO:0030317"(flagellated sperm motility)|go:"GO:0044853"(plasma membrane raft)|go:"GO:0046658"(anchored component of plasma membrane)|go:"GO:1901317"(regulation of flagellated sperm motility)|interpro:IPR016054(Ly-6 antigen / uPA receptor -like)|rcsb pdb:7BPR|reactome:R-HSA-163125|refseq:NP_001123483.1|refseq:NP_113639.4 ensembl:ENSG00000197061(gene)|ensembl:ENSG00000276180(gene)|ensembl:ENSG00000197238(gene)|ensembl:ENSG00000276966(gene)|ensembl:ENSG00000277157(gene)|ensembl:ENSG00000270276(gene)|ensembl:ENSG00000197837(gene)|ensembl:ENSG00000270882(gene)|ensembl:ENSG00000278637(gene)|ensembl:ENSG00000273542(gene)|ensembl:ENSG00000274618(gene)|ensembl:ENSG00000278705(gene)|ensembl:ENSG00000275126(gene)|ensembl:ENSG00000158406(gene)|dip:DIP-33079N|ensembl:ENST00000244537(transcript)|ensembl:ENST00000355057(transcript)|ensembl:ENST00000358064(transcript)|ensembl:ENST00000377727(transcript)|ensembl:ENST00000377745(transcript)|ensembl:ENST00000377803(transcript)|ensembl:ENST00000539745(transcript)|ensembl:ENST00000578186(transcript)|ensembl:ENST00000579512(transcript)|ensembl:ENST00000611927(transcript)|ensembl:ENST00000612061(transcript)|ensembl:ENST00000613412(transcript)|ensembl:ENST00000614247(transcript)|ensembl:ENST00000614272(transcript)|ensembl:ENST00000615164(transcript)|ensembl:ENST00000615353(transcript)|ensembl:ENST00000617569(transcript)|ensembl:ENST00000618193(transcript)|ensembl:ENST00000618305(transcript)|ensembl:ENST00000621520(transcript)|ensembl:ENST00000634560(transcript)|ensembl:ENST00000634956(transcript)|go:"GO:0000228"(nuclear chromosome)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0000786"(nucleosome)|go:"GO:0003677"(DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006334"(nucleosome assembly)|go:"GO:0006335"(DNA replication-dependent chromatin assembly)|go:"GO:0006336"(DNA replication-independent chromatin assembly)|go:"GO:0006352"(DNA-templated transcription, initiation)|go:"GO:0016020"(membrane)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0032200"(telomere organization)|go:"GO:0032991"(protein-containing complex)|go:"GO:0045653"(negative regulation of megakaryocyte differentiation)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0005576"(extracellular region)|go:"GO:0070062"(extracellular exosome)|interpro:IPR001951(Histone H4)|interpro:IPR004823("TATA box binding protein associated factor (TAF)")|rcsb pdb:3AZE|rcsb pdb:3AZF|rcsb pdb:3AZG|rcsb pdb:3AZH|rcsb pdb:3AZI|rcsb pdb:3AYW|rcsb pdb:3AZJ|rcsb pdb:3AZK|rcsb pdb:3AZL|rcsb pdb:3AZM|rcsb pdb:3AZN|rcsb pdb:3CFS|rcsb pdb:3CFV|rcsb pdb:3F9W|rcsb pdb:3F9X|rcsb pdb:3F9Y|rcsb pdb:3F9Z|rcsb pdb:3IJ1|rcsb pdb:3JPX|rcsb pdb:3NQJ|rcsb pdb:3NQU|rcsb pdb:3O36|rcsb pdb:3QBY|rcsb pdb:3QZS|rcsb pdb:3QZT|rcsb pdb:3QZV|rcsb pdb:3R45|rcsb pdb:3UVW|rcsb pdb:3UVX|rcsb pdb:3UVY|rcsb pdb:3UW9|rcsb pdb:3W96|rcsb pdb:3W97|rcsb pdb:3W98|rcsb pdb:3W99|rcsb pdb:3WA9|rcsb pdb:3WAA|rcsb pdb:3WKJ|rcsb pdb:3WTP|rcsb pdb:3X1S|rcsb pdb:3X1T|rcsb pdb:3X1U|rcsb pdb:3X1V|rcsb pdb:4GQB|rcsb pdb:4H9N|rcsb pdb:4H9O|rcsb pdb:4H9P|rcsb pdb:4H9Q|rcsb pdb:4H9R|rcsb pdb:4H9S|rcsb pdb:4HGA|rcsb pdb:4M38|rcsb pdb:4N3W|rcsb pdb:4N4F|rcsb pdb:4QUT|rcsb pdb:4QUU|rcsb pdb:4QYD|rcsb pdb:4U9W|rcsb pdb:4YM5|rcsb pdb:4YM6|rcsb pdb:4YY6|rcsb pdb:4YYD|rcsb pdb:4YYG|rcsb pdb:4YYH|rcsb pdb:4YYI|rcsb pdb:4YYJ|rcsb pdb:4YYK|rcsb pdb:4YYM|rcsb pdb:4YYN|rcsb pdb:4Z2M|rcsb pdb:4Z5T|rcsb pdb:5AV5|rcsb pdb:5AV6|rcsb pdb:5AV8|rcsb pdb:5AV9|rcsb pdb:5AVB|rcsb pdb:5AVC|rcsb pdb:5AY8|rcsb pdb:5B0Y|rcsb pdb:5B0Z|rcsb pdb:5B24|rcsb pdb:5B2I|rcsb pdb:5B2J|rcsb pdb:5B31|rcsb pdb:5B32|rcsb pdb:5B33|rcsb pdb:5B40|rcsb pdb:5BNV|rcsb pdb:5BNX|rcsb pdb:5BO0|rcsb pdb:5C3I|rcsb pdb:5CPI|interpro:IPR019809|interpro:IPR035425|mint:P62805|rcsb pdb:1ZKK|rcsb pdb:2BQZ|rcsb pdb:2CV5|rcsb pdb:2IG0|rcsb pdb:2KWN|rcsb pdb:2KWO|rcsb pdb:2LVM|rcsb pdb:2QQS|rcsb pdb:2RJE|rcsb pdb:2RNY|interpro:IPR009072(Histone-fold)|rcsb pdb:2RS9|rcsb pdb:3A6N|rcsb pdb:3AFA|rcsb pdb:3AN2|rcsb pdb:3AV1|rcsb pdb:3AV2|rcsb pdb:5GT3|rcsb pdb:5GTC|rcsb pdb:5GXQ|rcsb pdb:5JA4|rcsb pdb:5JRG|rcsb pdb:5KDM|rcsb pdb:5TEG|rcsb pdb:5X7X|rcsb pdb:5XF3|rcsb pdb:5XF4|rcsb pdb:5XF5|rcsb pdb:5Y0C|rcsb pdb:5Y0D|rcsb pdb:5YE3|rcsb pdb:5YE4|rcsb pdb:5Z23|rcsb pdb:5Z30|rcsb pdb:5ZBX|rcsb pdb:5ZGC|rcsb pdb:5CPJ|rcsb pdb:6A5L|rcsb pdb:6A5O|rcsb pdb:5CPK|rcsb pdb:6A5P|rcsb pdb:5FA5|rcsb pdb:6A5R|rcsb pdb:6A5T|rcsb pdb:6A5U|rcsb pdb:6ACP|rcsb pdb:6BUZ|rcsb pdb:6C0W|rcsb pdb:6E0C|rcsb pdb:6E0P|rcsb pdb:6FML|rcsb pdb:6HKT|rcsb pdb:6HTS|rcsb pdb:6INQ|rcsb pdb:6IR9|rcsb pdb:6J4W|rcsb pdb:6J4X|rcsb pdb:6J4Y|rcsb pdb:6J4Z|rcsb pdb:6J50|rcsb pdb:6J51|rcsb pdb:6JOU|rcsb pdb:6JR0|rcsb pdb:6JR1|rcsb pdb:6K1I|rcsb pdb:6K1J|rcsb pdb:6K1K|rcsb pdb:6KE9|rcsb pdb:6KVD|rcsb pdb:6KXV|rcsb pdb:6L49|rcsb pdb:6L4A|rcsb pdb:6L9H|rcsb pdb:6L9Z|rcsb pdb:6LA2|rcsb pdb:6LA8|rcsb pdb:6LA9|rcsb pdb:6LAB|rcsb pdb:6LE9|rcsb pdb:6LER|rcsb pdb:6M3V|rcsb pdb:6M44|rcsb pdb:6M4D|rcsb pdb:5FFW|rcsb pdb:5FWE|rcsb pdb:5GSE|rcsb pdb:5GSU|rcsb pdb:5GT0|rcsb pdb:6M4G|rcsb pdb:6M4H|rcsb pdb:6MLC|rcsb pdb:6MUO|rcsb pdb:6MUP|rcsb pdb:6O1D|rcsb pdb:6R0C|rcsb pdb:6R8Y|rcsb pdb:6R8Z|rcsb pdb:6R90|rcsb pdb:6R91|refseq:NP_001029249.1|refseq:NP_003486.1|refseq:NP_003529.1|refseq:NP_003530.1|refseq:NP_003531.1|refseq:NP_003532.1|refseq:NP_003533.1|refseq:NP_003534.1|refseq:NP_003535.1|refseq:NP_003536.1|refseq:NP_003537.1|refseq:NP_003539.1|rcsb pdb:6R92|rcsb pdb:6R93|rcsb pdb:6R94|rcsb pdb:6RNY|rcsb pdb:6RXS|rcsb pdb:6SE0|rcsb pdb:6SE6|rcsb pdb:6SEE|rcsb pdb:6SEF|rcsb pdb:6SEG|rcsb pdb:6T79|rcsb pdb:6T7A|rcsb pdb:6T7B|rcsb pdb:6T7C|rcsb pdb:6T7D|rcsb pdb:6T90|rcsb pdb:6T93|rcsb pdb:6UPK|rcsb pdb:6UPL|rcsb pdb:6USJ|rcsb pdb:6V2K|rcsb pdb:6V92|rcsb pdb:6VO5|rcsb pdb:6X59|rcsb pdb:6X5A|rcsb pdb:6XJD|rcsb pdb:6Y5D|rcsb pdb:6YOV|rcsb pdb:7A08|rcsb pdb:7BWD|rcsb pdb:7BXT|rcsb pdb:7BY0|rcsb pdb:7C0M|rcsb pdb:7CCQ|rcsb pdb:7CCR|rcsb pdb:7CIZ|rcsb pdb:7CJ0|rcsb pdb:7D1Z|rcsb pdb:7D20|rcsb pdb:7DBP|rcsb pdb:7JO9|rcsb pdb:7JOA|rcsb pdb:7JZV|rcsb pdb:7K5X|rcsb pdb:7K5Y|rcsb pdb:7K60|rcsb pdb:7K61|rcsb pdb:7K63|rcsb pdb:7LMK|rcsb pdb:7LMM|rcsb pdb:7LYC|reactome:R-HSA-110328|reactome:R-HSA-110329|reactome:R-HSA-110330|reactome:R-HSA-110331|reactome:R-HSA-1221632|reactome:R-HSA-171306|reactome:R-HSA-1912408|reactome:R-HSA-201722|reactome:R-HSA-212300|reactome:R-HSA-2299718|reactome:R-HSA-2559580|reactome:R-HSA-2559582|reactome:R-HSA-2559586|reactome:R-HSA-3214815|reactome:R-HSA-3214841|reactome:R-HSA-3214842|reactome:R-HSA-3214847|reactome:R-HSA-3214858|reactome:R-HSA-427359|reactome:R-HSA-427389|reactome:R-HSA-427413|reactome:R-HSA-4551638|reactome:R-HSA-5250924|reactome:R-HSA-5334118|reactome:R-HSA-5578749|reactome:R-HSA-5617472|reactome:R-HSA-5625886|reactome:R-HSA-5693565|refseq:NP_068803.1|refseq:NP_778224.1|reactome:R-HSA-5693571|reactome:R-HSA-5693607|reactome:R-HSA-606279|reactome:R-HSA-69473|reactome:R-HSA-73728|reactome:R-HSA-73772|reactome:R-HSA-8936459|reactome:R-HSA-8939236|reactome:R-HSA-9018519|reactome:R-HSA-912446|reactome:R-HSA-9609690|reactome:R-HSA-9610379|reactome:R-HSA-9616222|reactome:R-HSA-9670095|reactome:R-HSA-9710421|reactome:R-HSA-977225 - - - comment:"Proteins significantly enriched by immunoprecipitation with 34ED556 (T1) anti-TEX101 antibody in human seminal plasma from pre-vasectomy semen samples."|figure legend:Fig. 2C, supplemental Table S7|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-seminal _fluid)|taxid:9606(Human seminal fluid) - 2020/03/24 2020/04/07 rogid:ZE4tXTFi7lUCcIbCL4KHzY3a6xM9606 rogid:LZSfhrpw0PcDREEoJ1UMkBvnUfA9606 rigid:pks5IYYH9Nc4ZJXDIjAUAp2Xj7s false - - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q9BY14 uniprotkb:P20142 intact:EBI-12549378|ensembl:ENSP00000472769|uniprotkb:Q7L5R2|uniprotkb:Q9BPY7 intact:EBI-25505421|ensembl:ENSP00000362116|uniprotkb:B4DVZ3|uniprotkb:Q5T3D7|uniprotkb:Q5T3D8 psi-mi:tx101_human(display_long)|uniprotkb:TEX101(gene name)|psi-mi:TEX101(display_short)|uniprotkb:Cell surface receptor NYD-SP8(gene name synonym)|uniprotkb:SGRG(gene name synonym)|uniprotkb:Scleroderma-associated autoantigen(gene name synonym)|uniprotkb:Spermatogenesis-related gene protein(gene name synonym)|uniprotkb:UNQ867/PRO1884(orf name) psi-mi:pepc_human(display_long)|uniprotkb:PGC(gene name)|psi-mi:PGC(display_short)|uniprotkb:Pepsinogen C(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Schiza et al. (2018) imex:IM-28077|pubmed:30097533 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-25505663|imex:IM-28077-9 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000131126(gene)|ensembl:ENST00000598265(transcript)|go:"GO:0001669"(acrosomal vesicle)|go:"GO:0002080"(acrosomal membrane)|go:"GO:0005576"(extracellular region)|go:"GO:0005886"(plasma membrane)|go:"GO:0007339"(binding of sperm to zona pellucida)|go:"GO:0009566"(fertilization)|go:"GO:0030317"(flagellated sperm motility)|go:"GO:0044853"(plasma membrane raft)|go:"GO:0046658"(anchored component of plasma membrane)|go:"GO:1901317"(regulation of flagellated sperm motility)|interpro:IPR016054(Ly-6 antigen / uPA receptor -like)|rcsb pdb:7BPR|reactome:R-HSA-163125|refseq:NP_001123483.1|refseq:NP_113639.4 ensembl:ENST00000373025(transcript)|go:"GO:0002803"(positive regulation of antibacterial peptide production)|go:"GO:0004190"(aspartic-type endopeptidase activity)|go:"GO:0005615"(extracellular space)|go:"GO:0006508"(proteolysis)|go:"GO:0007586"(digestion)|interpro:IPR001461(Peptidase A1)|interpro:IPR001969(Peptidase aspartic, active site)|interpro:IPR012848(Propeptide, peptidase A1)|interpro:IPR021109|interpro:IPR033121|interpro:IPR033735|rcsb pdb:1AVF|rcsb pdb:1HTR|ensembl:ENSG00000096088(gene)|refseq:NP_001159896.1|refseq:NP_002621.1 - - - comment:"Proteins significantly enriched by immunoprecipitation with 34ED556 (T1) anti-TEX101 antibody in human seminal plasma from pre-vasectomy semen samples."|figure legend:Fig. 2C, supplemental Table S7|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-seminal _fluid)|taxid:9606(Human seminal fluid) - 2020/03/24 2020/04/07 rogid:ZE4tXTFi7lUCcIbCL4KHzY3a6xM9606 rogid:2eQsQY3Un7S8Be8awfIyzQTmdUI9606 rigid:pks5IYYH9Nc4ZJXDIjAUAp2Xj7s false - - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q9BY14 uniprotkb:P11717 intact:EBI-12549378|ensembl:ENSP00000472769|uniprotkb:Q7L5R2|uniprotkb:Q9BPY7 intact:EBI-1048580|uniprotkb:Q7Z7G9|uniprotkb:Q96PT5|ensembl:ENSP00000349437 psi-mi:tx101_human(display_long)|uniprotkb:TEX101(gene name)|psi-mi:TEX101(display_short)|uniprotkb:Cell surface receptor NYD-SP8(gene name synonym)|uniprotkb:SGRG(gene name synonym)|uniprotkb:Scleroderma-associated autoantigen(gene name synonym)|uniprotkb:Spermatogenesis-related gene protein(gene name synonym)|uniprotkb:UNQ867/PRO1884(orf name) psi-mi:mpri_human(display_long)|uniprotkb:Insulin-like growth factor 2 receptor(gene name synonym)|uniprotkb:Insulin-like growth factor II receptor(gene name synonym)|uniprotkb:M6P/IGF2 receptor(gene name synonym)|uniprotkb:300 kDa mannose 6-phosphate receptor(gene name synonym)|uniprotkb:IGF2R(gene name)|psi-mi:IGF2R(display_short)|uniprotkb:MPRI(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Schiza et al. (2018) imex:IM-28077|pubmed:30097533 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-25505663|imex:IM-28077-9 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000131126(gene)|ensembl:ENST00000598265(transcript)|go:"GO:0001669"(acrosomal vesicle)|go:"GO:0002080"(acrosomal membrane)|go:"GO:0005576"(extracellular region)|go:"GO:0005886"(plasma membrane)|go:"GO:0007339"(binding of sperm to zona pellucida)|go:"GO:0009566"(fertilization)|go:"GO:0030317"(flagellated sperm motility)|go:"GO:0044853"(plasma membrane raft)|go:"GO:0046658"(anchored component of plasma membrane)|go:"GO:1901317"(regulation of flagellated sperm motility)|interpro:IPR016054(Ly-6 antigen / uPA receptor -like)|rcsb pdb:7BPR|reactome:R-HSA-163125|refseq:NP_001123483.1|refseq:NP_113639.4 refseq:NP_000867.2|go:"GO:0001965"(G-protein alpha-subunit binding)|go:"GO:0001972"(retinoic acid binding)|go:"GO:0005010"(insulin-like growth factor-activated receptor activity)|go:"GO:0005520"(insulin-like growth factor binding)|go:"GO:0005537"(mannose binding)|go:"GO:0005641"(nuclear envelope lumen)|go:"GO:0005768"(endosome)|go:"GO:0005769"(early endosome)|go:"GO:0005770"(late endosome)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0005925"(focal adhesion)|go:"GO:0006898"(receptor-mediated endocytosis)|ensembl:ENSG00000197081(gene)|go:"GO:0007041"(lysosomal transport)|go:"GO:0007165"(signal transduction)|ensembl:ENST00000356956(transcript)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0001889"(liver development)|go:"GO:0007283"(spermatogenesis)|go:"GO:0009791"(post-embryonic development)|go:"GO:0009986"(cell surface)|go:"GO:0010008"(endosome membrane)|go:"GO:0016020"(membrane)|go:"GO:0019899"(enzyme binding)|go:"GO:0030118"(clathrin coat)|go:"GO:0030133"(transport vesicle)|go:"GO:0030139"(endocytic vesicle)|go:"GO:0030140"(trans-Golgi network transport vesicle)|go:"GO:0030667"(secretory granule membrane)|go:"GO:0030669"(clathrin-coated endocytic vesicle membrane)|go:"GO:0031100"(animal organ regeneration)|go:"GO:0031995"(insulin-like growth factor II binding)|go:"GO:0032526"(response to retinoic acid)|go:"GO:0032588"(trans-Golgi network membrane)|go:"GO:0038023"(signaling receptor activity)|go:"GO:0042802"(identical protein binding)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0044794"(positive regulation by host of viral process)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051219"(phosphoprotein binding)|go:"GO:0070062"(extracellular exosome)|go:"GO:1904772"(response to tetrachloromethane)|go:"GO:1905394"(retromer complex binding)|interpro:IPR000479(Cation-independent mannose-6-phosphate receptor)|interpro:IPR000562(Type II fibronectin, collagen-binding)|interpro:IPR009011(Mannose-6-phosphate receptor, binding)|interpro:IPR013806(Kringle-like fold)|interpro:IPR036943|interpro:IPR044865|mint:P11717|rcsb pdb:1E6F|rcsb pdb:1GP0|rcsb pdb:1GP3|rcsb pdb:1GQB|rcsb pdb:1JPL|rcsb pdb:1JWG|rcsb pdb:1LF8|rcsb pdb:2CNJ|rcsb pdb:2L29|rcsb pdb:2L2A|rcsb pdb:2M68|rcsb pdb:2M6T|rcsb pdb:2V5N|rcsb pdb:2V5O|rcsb pdb:2V5P|rcsb pdb:5IEI|rcsb pdb:6N5X|rcsb pdb:6N5Y|rcsb pdb:6P8I|rcsb pdb:6V02|rcsb pdb:6Z30|rcsb pdb:6Z31|rcsb pdb:6Z32|reactome:R-HSA-432722|reactome:R-HSA-6798695|reactome:R-HSA-6811440|reactome:R-HSA-8856825|reactome:R-HSA-8856828|dip:DIP-6027N - - - comment:"Proteins significantly enriched by immunoprecipitation with 34ED556 (T1) anti-TEX101 antibody in human seminal plasma from pre-vasectomy semen samples."|figure legend:Fig. 2C, supplemental Table S7|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-seminal _fluid)|taxid:9606(Human seminal fluid) - 2020/03/24 2020/04/07 rogid:ZE4tXTFi7lUCcIbCL4KHzY3a6xM9606 rogid:7lkG6WR8MQ/SONiTV/8g1ZTtKTU9606 rigid:pks5IYYH9Nc4ZJXDIjAUAp2Xj7s false - - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q9BY14 uniprotkb:P35626 intact:EBI-12549378|ensembl:ENSP00000472769|uniprotkb:Q7L5R2|uniprotkb:Q9BPY7 intact:EBI-2875868|ensembl:ENSP00000317578|uniprotkb:Q9UGW9 psi-mi:tx101_human(display_long)|uniprotkb:TEX101(gene name)|psi-mi:TEX101(display_short)|uniprotkb:Cell surface receptor NYD-SP8(gene name synonym)|uniprotkb:SGRG(gene name synonym)|uniprotkb:Scleroderma-associated autoantigen(gene name synonym)|uniprotkb:Spermatogenesis-related gene protein(gene name synonym)|uniprotkb:UNQ867/PRO1884(orf name) psi-mi:arbk2_human(display_long)|uniprotkb:GRK3(gene name)|psi-mi:GRK3(display_short)|uniprotkb:ADRBK2(gene name synonym)|uniprotkb:BARK2(gene name synonym)|uniprotkb:G-protein-coupled receptor kinase 3(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Schiza et al. (2018) imex:IM-28077|pubmed:30097533 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-25505663|imex:IM-28077-9 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000131126(gene)|ensembl:ENST00000598265(transcript)|go:"GO:0001669"(acrosomal vesicle)|go:"GO:0002080"(acrosomal membrane)|go:"GO:0005576"(extracellular region)|go:"GO:0005886"(plasma membrane)|go:"GO:0007339"(binding of sperm to zona pellucida)|go:"GO:0009566"(fertilization)|go:"GO:0030317"(flagellated sperm motility)|go:"GO:0044853"(plasma membrane raft)|go:"GO:0046658"(anchored component of plasma membrane)|go:"GO:1901317"(regulation of flagellated sperm motility)|interpro:IPR016054(Ly-6 antigen / uPA receptor -like)|rcsb pdb:7BPR|reactome:R-HSA-163125|refseq:NP_001123483.1|refseq:NP_113639.4 go:"GO:0006468"(protein phosphorylation)|go:"GO:0007165"(signal transduction)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0009966"(regulation of signal transduction)|go:"GO:0031623"(receptor internalization)|go:"GO:0047696"(beta-adrenergic receptor kinase activity)|interpro:IPR000239(GPCR kinase)|interpro:IPR000719(Protein kinase, core)|interpro:IPR000961(Protein kinase, C-terminal)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR008271(Serine/threonine protein kinase, active site)|go:"GO:0005886"(plasma membrane)|interpro:IPR011009(Protein kinase-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR016137(Regulator of G protein signalling superfamily)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR036305|reactome:R-HSA-418555|reactome:R-HSA-8856825|ensembl:ENSG00000100077(gene)|ensembl:ENST00000324198(transcript)|go:"GO:0001664"(G protein-coupled receptor binding)|go:"GO:0002029"(desensitization of G protein-coupled receptor signaling pathway)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004703"(G protein-coupled receptor kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005829"(cytosol)|refseq:NP_005151.2 - - - comment:"Proteins significantly enriched by immunoprecipitation with 34ED556 (T1) anti-TEX101 antibody in human seminal plasma from pre-vasectomy semen samples."|figure legend:Fig. 2C, supplemental Table S7|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-seminal _fluid)|taxid:9606(Human seminal fluid) - 2020/03/24 2020/04/07 rogid:ZE4tXTFi7lUCcIbCL4KHzY3a6xM9606 rogid:IXh7IeKOJ35sBT4TzFHPNB1xhnE9606 rigid:pks5IYYH9Nc4ZJXDIjAUAp2Xj7s false - - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q9BY14 uniprotkb:Q7Z406 intact:EBI-12549378|ensembl:ENSP00000472769|uniprotkb:Q7L5R2|uniprotkb:Q9BPY7 intact:EBI-355595|uniprotkb:Q5CZ75|uniprotkb:Q6XYE4|uniprotkb:Q76B62|uniprotkb:Q8WV23|uniprotkb:Q96I22|uniprotkb:Q9BT27|uniprotkb:Q9BW35|uniprotkb:Q9H882|uniprotkb:B0I1S2|ensembl:ENSP00000366169|ensembl:ENSP00000472819|uniprotkb:C3TTN4 psi-mi:tx101_human(display_long)|uniprotkb:TEX101(gene name)|psi-mi:TEX101(display_short)|uniprotkb:Cell surface receptor NYD-SP8(gene name synonym)|uniprotkb:SGRG(gene name synonym)|uniprotkb:Scleroderma-associated autoantigen(gene name synonym)|uniprotkb:Spermatogenesis-related gene protein(gene name synonym)|uniprotkb:UNQ867/PRO1884(orf name) psi-mi:myh14_human(display_long)|uniprotkb:MYH14(gene name)|psi-mi:MYH14(display_short)|uniprotkb:KIAA2034(gene name synonym)|uniprotkb:FP17425(orf name)|uniprotkb:Myosin heavy chain 14(gene name synonym)|uniprotkb:Myosin heavy chain, non-muscle IIc(gene name synonym)|uniprotkb:Non-muscle myosin heavy chain IIc(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Schiza et al. (2018) imex:IM-28077|pubmed:30097533 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-25505663|imex:IM-28077-9 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000131126(gene)|ensembl:ENST00000598265(transcript)|go:"GO:0001669"(acrosomal vesicle)|go:"GO:0002080"(acrosomal membrane)|go:"GO:0005576"(extracellular region)|go:"GO:0005886"(plasma membrane)|go:"GO:0007339"(binding of sperm to zona pellucida)|go:"GO:0009566"(fertilization)|go:"GO:0030317"(flagellated sperm motility)|go:"GO:0044853"(plasma membrane raft)|go:"GO:0046658"(anchored component of plasma membrane)|go:"GO:1901317"(regulation of flagellated sperm motility)|interpro:IPR016054(Ly-6 antigen / uPA receptor -like)|rcsb pdb:7BPR|reactome:R-HSA-163125|refseq:NP_001123483.1|refseq:NP_113639.4 refseq:NP_001070654.1|refseq:NP_001139281.1|refseq:NP_079005.3|refseq:XP_011525625.1|ensembl:ENSG00000105357(gene)|ensembl:ENST00000376970(transcript)|ensembl:ENST00000596571(transcript)|go:"GO:0000146"(microfilament motor activity)|go:"GO:0001725"(stress fiber)|go:"GO:0003009"(skeletal muscle contraction)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005829"(cytosol)|go:"GO:0005903"(brush border)|go:"GO:0007519"(skeletal muscle tissue development)|go:"GO:0007605"(sensory perception of sound)|go:"GO:0008360"(regulation of cell shape)|go:"GO:0016020"(membrane)|go:"GO:0016460"(myosin II complex)|go:"GO:0016887"(ATP hydrolysis activity)|go:"GO:0019228"(neuronal action potential)|go:"GO:0030048"(actin filament-based movement)|go:"GO:0030426"(growth cone)|go:"GO:0031032"(actomyosin structure organization)|go:"GO:0042641"(actomyosin)|go:"GO:0051015"(actin filament binding)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070584"(mitochondrion morphogenesis)|go:"GO:0071625"(vocalization behavior)|go:"GO:0097513"(myosin II filament)|interpro:IPR000048(IQ calmodulin-binding region)|interpro:IPR001609(Myosin head, motor region)|interpro:IPR004009(Myosin, N-terminal, SH3-like)|interpro:IPR008989(Myosin S1 fragment, N-terminal)|interpro:IPR027417|interpro:IPR036961|mint:Q7Z406|rcsb pdb:5I4E|rcsb pdb:5JLH|reactome:R-HSA-3928663|reactome:R-HSA-416572|reactome:R-HSA-5625740|reactome:R-HSA-5625900|reactome:R-HSA-5627117|reactome:R-HSA-5627123|interpro:IPR002928(Myosin tail)|refseq:XP_006723449.1|dip:DIP-33170N - - - comment:"Proteins significantly enriched by immunoprecipitation with 34ED556 (T1) anti-TEX101 antibody in human seminal plasma from pre-vasectomy semen samples."|figure legend:Fig. 2C, supplemental Table S7|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-seminal _fluid)|taxid:9606(Human seminal fluid) - 2020/03/24 2020/04/07 rogid:ZE4tXTFi7lUCcIbCL4KHzY3a6xM9606 rogid:6aY3HPa5DIY5UadiOTTh/uSPi/M9606 rigid:pks5IYYH9Nc4ZJXDIjAUAp2Xj7s false - - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q9BY14 uniprotkb:P13987 intact:EBI-12549378|ensembl:ENSP00000472769|uniprotkb:Q7L5R2|uniprotkb:Q9BPY7 intact:EBI-297972|ensembl:ENSP00000340210|ensembl:ENSP00000379191|ensembl:ENSP00000403511|ensembl:ENSP00000404822|ensembl:ENSP00000410182|ensembl:ENSP00000432942|ensembl:ENSP00000494884|ensembl:ENSP00000498448|ensembl:ENSP00000498879|uniprotkb:E9PR17 psi-mi:tx101_human(display_long)|uniprotkb:TEX101(gene name)|psi-mi:TEX101(display_short)|uniprotkb:Cell surface receptor NYD-SP8(gene name synonym)|uniprotkb:SGRG(gene name synonym)|uniprotkb:Scleroderma-associated autoantigen(gene name synonym)|uniprotkb:Spermatogenesis-related gene protein(gene name synonym)|uniprotkb:UNQ867/PRO1884(orf name) psi-mi:cd59_human(display_long)|uniprotkb:CD59(gene name)|psi-mi:CD59(display_short)|uniprotkb:Membrane attack complex inhibition factor(gene name synonym)|uniprotkb:MAC-inhibitory protein(gene name synonym)|uniprotkb:Protectin(gene name synonym)|uniprotkb:MEM43 antigen(gene name synonym)|uniprotkb:Membrane inhibitor of reactive lysis(gene name synonym)|uniprotkb:20 kDa homologous restriction factor(gene name synonym)|uniprotkb:1F5 antigen(gene name synonym)|uniprotkb:MIC11(gene name synonym)|uniprotkb:MIN1(gene name synonym)|uniprotkb:MIN2(gene name synonym)|uniprotkb:MIN3(gene name synonym)|uniprotkb:MSK21(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Schiza et al. (2018) imex:IM-28077|pubmed:30097533 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-25505704|imex:IM-28077-11 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000131126(gene)|ensembl:ENST00000598265(transcript)|go:"GO:0001669"(acrosomal vesicle)|go:"GO:0002080"(acrosomal membrane)|go:"GO:0005576"(extracellular region)|go:"GO:0005886"(plasma membrane)|go:"GO:0007339"(binding of sperm to zona pellucida)|go:"GO:0009566"(fertilization)|go:"GO:0030317"(flagellated sperm motility)|go:"GO:0044853"(plasma membrane raft)|go:"GO:0046658"(anchored component of plasma membrane)|go:"GO:1901317"(regulation of flagellated sperm motility)|interpro:IPR016054(Ly-6 antigen / uPA receptor -like)|rcsb pdb:7BPR|reactome:R-HSA-163125|refseq:NP_001123483.1|refseq:NP_113639.4 refseq:NP_000602.1|refseq:NP_001120695.1|refseq:NP_001120697.1|refseq:NP_001120698.1|refseq:NP_001120699.1|refseq:NP_976074.1|refseq:NP_976075.1|refseq:NP_976076.1|ensembl:ENST00000395850(transcript)|ensembl:ENST00000415002(transcript)|ensembl:ENST00000437761(transcript)|ensembl:ENST00000445143(transcript)|ensembl:ENST00000527577(transcript)|ensembl:ENST00000642928(transcript)|ensembl:ENST00000651785(transcript)|ensembl:ENST00000652678(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001848"(complement binding)|go:"GO:0001971"(negative regulation of activation of membrane attack complex)|go:"GO:0005615"(extracellular space)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005886"(plasma membrane)|go:"GO:0005925"(focal adhesion)|go:"GO:0007166"(cell surface receptor signaling pathway)|go:"GO:0007596"(blood coagulation)|go:"GO:0009986"(cell surface)|go:"GO:0012507"(ER to Golgi transport vesicle membrane)|go:"GO:0016020"(membrane)|go:"GO:0030133"(transport vesicle)|go:"GO:0030449"(regulation of complement activation)|go:"GO:0031362"(anchored component of external side of plasma membrane)|go:"GO:0031982"(vesicle)|go:"GO:0033116"(endoplasmic reticulum-Golgi intermediate compartment membrane)|go:"GO:0035579"(specific granule membrane)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070821"(tertiary granule membrane)|go:"GO:1903659"(regulation of complement-dependent cytotoxicity)|interpro:IPR016054(Ly-6 antigen / uPA receptor -like)|interpro:IPR018363|interpro:IPR027101|mint:P13987|rcsb pdb:1CDQ|rcsb pdb:1CDR|rcsb pdb:1CDS|rcsb pdb:1ERG|rcsb pdb:1ERH|rcsb pdb:2J8B|rcsb pdb:2OFS|rcsb pdb:2UWR|rcsb pdb:2UX2|rcsb pdb:4BIK|rcsb pdb:5IMT|rcsb pdb:5IMY|rcsb pdb:6ZD0|reactome:R-HSA-204005|reactome:R-HSA-5694530|reactome:R-HSA-6798695|reactome:R-HSA-6807878|reactome:R-HSA-977606|ensembl:ENSG00000085063(gene)|ensembl:ENST00000351554(transcript) - - - figure legend:Fig. 3B and Table I|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-spermatozoa)|taxid:9606(Homo sapiens) - 2020/03/24 2020/04/07 rogid:ZE4tXTFi7lUCcIbCL4KHzY3a6xM9606 rogid:l93Yw04Ax0xODyPzjFqaaMvqBeM9606 rigid:Yhx0rOseaBytn3hdnMzCaibVOLg false - - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q9BY14 uniprotkb:P12821 intact:EBI-12549378|ensembl:ENSP00000472769|uniprotkb:Q7L5R2|uniprotkb:Q9BPY7 intact:EBI-9512350|uniprotkb:B0LPF0|uniprotkb:B4DXI3|uniprotkb:E7EU16|uniprotkb:P22966|uniprotkb:Q53YX9|uniprotkb:Q59GY8|uniprotkb:Q7M4L4|ensembl:ENSP00000290866 psi-mi:tx101_human(display_long)|uniprotkb:TEX101(gene name)|psi-mi:TEX101(display_short)|uniprotkb:Cell surface receptor NYD-SP8(gene name synonym)|uniprotkb:SGRG(gene name synonym)|uniprotkb:Scleroderma-associated autoantigen(gene name synonym)|uniprotkb:Spermatogenesis-related gene protein(gene name synonym)|uniprotkb:UNQ867/PRO1884(orf name) psi-mi:ace_human(display_long)|uniprotkb:ACE(gene name)|psi-mi:ACE(display_short)|uniprotkb:DCP(gene name synonym)|uniprotkb:DCP1(gene name synonym)|uniprotkb:Dipeptidyl carboxypeptidase I(gene name synonym)|uniprotkb:Kininase II(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Schiza et al. (2018) imex:IM-28077|pubmed:30097533 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-25505704|imex:IM-28077-11 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000131126(gene)|ensembl:ENST00000598265(transcript)|go:"GO:0001669"(acrosomal vesicle)|go:"GO:0002080"(acrosomal membrane)|go:"GO:0005576"(extracellular region)|go:"GO:0005886"(plasma membrane)|go:"GO:0007339"(binding of sperm to zona pellucida)|go:"GO:0009566"(fertilization)|go:"GO:0030317"(flagellated sperm motility)|go:"GO:0044853"(plasma membrane raft)|go:"GO:0046658"(anchored component of plasma membrane)|go:"GO:1901317"(regulation of flagellated sperm motility)|interpro:IPR016054(Ly-6 antigen / uPA receptor -like)|rcsb pdb:7BPR|reactome:R-HSA-163125|refseq:NP_001123483.1|refseq:NP_113639.4 refseq:NP_000780.1|refseq:NP_001171528.1|refseq:NP_690043.1|ensembl:ENSG00000159640(gene)|ensembl:ENST00000290866(transcript)|go:"GO:0001822"(kidney development)|go:"GO:0001974"(blood vessel remodeling)|go:"GO:0002003"(angiotensin maturation)|go:"GO:0002019"(regulation of renal output by angiotensin)|go:"GO:0002446"(neutrophil mediated immunity)|go:"GO:0002474"(antigen processing and presentation of peptide antigen via MHC class I)|go:"GO:0003081"(regulation of systemic arterial blood pressure by renin-angiotensin)|go:"GO:0003084"(positive regulation of systemic arterial blood pressure)|go:"GO:0003779"(actin binding)|go:"GO:0004175"(endopeptidase activity)|go:"GO:0004180"(carboxypeptidase activity)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0005764"(lysosome)|go:"GO:0005768"(endosome)|go:"GO:0005886"(plasma membrane)|go:"GO:0006508"(proteolysis)|go:"GO:0007283"(spermatogenesis)|go:"GO:0008217"(regulation of blood pressure)|go:"GO:0008237"(metallopeptidase activity)|go:"GO:0008238"(exopeptidase activity)|go:"GO:0008240"(tripeptidyl-peptidase activity)|go:"GO:0008241"(peptidyl-dipeptidase activity)|go:"GO:0008270"(zinc ion binding)|go:"GO:0009897"(external side of plasma membrane)|go:"GO:0010608"(posttranscriptional regulation of gene expression)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0014910"(regulation of smooth muscle cell migration)|go:"GO:0016021"(integral component of membrane)|go:"GO:0019229"(regulation of vasoconstriction)|go:"GO:0031404"(chloride ion binding)|go:"GO:0031434"(mitogen-activated protein kinase kinase binding)|go:"GO:0031711"(bradykinin receptor binding)|go:"GO:0032091"(negative regulation of protein binding)|go:"GO:0032092"(positive regulation of protein binding)|go:"GO:0032943"(mononuclear cell proliferation)|go:"GO:0042447"(hormone catabolic process)|go:"GO:0043171"(peptide catabolic process)|go:"GO:0050435"(amyloid-beta metabolic process)|go:"GO:0050482"(arachidonic acid secretion)|go:"GO:0051019"(mitogen-activated protein kinase binding)|go:"GO:0060047"(heart contraction)|go:"GO:0060177"(regulation of angiotensin metabolic process)|go:"GO:0060218"(hematopoietic stem cell differentiation)|go:"GO:0061098"(positive regulation of protein tyrosine kinase activity)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070573"(metallodipeptidase activity)|go:"GO:0071838"(cell proliferation in bone marrow)|go:"GO:0097746"(blood vessel diameter maintenance)|go:"GO:1900086"(positive regulation of peptidyl-tyrosine autophosphorylation)|go:"GO:1902033"(regulation of hematopoietic stem cell proliferation)|go:"GO:1903597"(negative regulation of gap junction assembly)|go:"GO:2000170"(positive regulation of peptidyl-cysteine S-nitrosylation)|interpro:IPR001548(Peptidase M2, peptidyl-dipeptidase A)|mint:P12821|rcsb pdb:1O86|rcsb pdb:1O8A|rcsb pdb:1UZE|rcsb pdb:1UZF|rcsb pdb:2C6F|rcsb pdb:2C6N|rcsb pdb:2IUL|rcsb pdb:2IUX|rcsb pdb:2OC2|rcsb pdb:2XY9|rcsb pdb:2XYD|rcsb pdb:2YDM|rcsb pdb:3BKK|rcsb pdb:3BKL|rcsb pdb:3L3N|rcsb pdb:3NXQ|rcsb pdb:4APH|rcsb pdb:4APJ|rcsb pdb:4BXK|rcsb pdb:4BZR|rcsb pdb:4BZS|rcsb pdb:4C2N|rcsb pdb:4C2O|rcsb pdb:4C2P|rcsb pdb:4C2Q|rcsb pdb:4C2R|rcsb pdb:4CA5|rcsb pdb:4CA6|rcsb pdb:4UFA|rcsb pdb:4UFB|rcsb pdb:5AM8|rcsb pdb:5AM9|rcsb pdb:5AMA|rcsb pdb:5AMB|rcsb pdb:5AMC|rcsb pdb:6EN5|rcsb pdb:6EN6|rcsb pdb:6F9R|rcsb pdb:6F9T|rcsb pdb:6F9U|rcsb pdb:6F9V|rcsb pdb:6H5W|rcsb pdb:6H5X|rcsb pdb:6QS1|rcsb pdb:6TT1|rcsb pdb:6TT3|rcsb pdb:6TT4|rcsb pdb:6ZPQ|rcsb pdb:6ZPT|rcsb pdb:6ZPU|reactome:R-HSA-2022377 - - - figure legend:Fig. 3B and Table I|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-spermatozoa)|taxid:9606(Homo sapiens) - 2020/03/24 2020/04/07 rogid:ZE4tXTFi7lUCcIbCL4KHzY3a6xM9606 rogid:Ta44N/vjlStlVIzNX634OjHzyrM9606 rigid:Yhx0rOseaBytn3hdnMzCaibVOLg false - - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q9BY14 uniprotkb:Q9H4B8 intact:EBI-12549378|ensembl:ENSP00000472769|uniprotkb:Q7L5R2|uniprotkb:Q9BPY7 intact:EBI-20843342|ensembl:ENSP00000268793|uniprotkb:B3KQ48|uniprotkb:Q6PEZ5|uniprotkb:Q6UXE4 psi-mi:tx101_human(display_long)|uniprotkb:TEX101(gene name)|psi-mi:TEX101(display_short)|uniprotkb:Cell surface receptor NYD-SP8(gene name synonym)|uniprotkb:SGRG(gene name synonym)|uniprotkb:Scleroderma-associated autoantigen(gene name synonym)|uniprotkb:Spermatogenesis-related gene protein(gene name synonym)|uniprotkb:UNQ867/PRO1884(orf name) psi-mi:dpep3_human(display_long)|uniprotkb:DPEP3(gene name)|psi-mi:DPEP3(display_short)|uniprotkb:UNQ834/PRO1772(orf name) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Schiza et al. (2018) imex:IM-28077|pubmed:30097533 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-25505704|imex:IM-28077-11 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000131126(gene)|ensembl:ENST00000598265(transcript)|go:"GO:0001669"(acrosomal vesicle)|go:"GO:0002080"(acrosomal membrane)|go:"GO:0005576"(extracellular region)|go:"GO:0005886"(plasma membrane)|go:"GO:0007339"(binding of sperm to zona pellucida)|go:"GO:0009566"(fertilization)|go:"GO:0030317"(flagellated sperm motility)|go:"GO:0044853"(plasma membrane raft)|go:"GO:0046658"(anchored component of plasma membrane)|go:"GO:1901317"(regulation of flagellated sperm motility)|interpro:IPR016054(Ly-6 antigen / uPA receptor -like)|rcsb pdb:7BPR|reactome:R-HSA-163125|refseq:NP_001123483.1|refseq:NP_113639.4 ensembl:ENSG00000141096(gene)|ensembl:ENST00000268793(transcript)|go:"GO:0001669"(acrosomal vesicle)|go:"GO:0005886"(plasma membrane)|go:"GO:0016805"(dipeptidase activity)|go:"GO:0031225"(anchored component of membrane)|go:"GO:0046872"(metal ion binding)|go:"GO:0070573"(metallodipeptidase activity)|interpro:IPR000180(Peptidase M19, renal dipeptidase, active site)|interpro:IPR008257(Peptidase M19, renal dipeptidase)|interpro:IPR028531|interpro:IPR032466|rcsb pdb:6VGO|rcsb pdb:6VGR|reactome:R-HSA-2142691|reactome:R-HSA-5423646|reactome:R-HSA-9664535|refseq:NP_001123230.1|refseq:NP_071752.3 - - - figure legend:Fig. 3B and Table I|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-spermatozoa)|taxid:9606(Homo sapiens) - 2020/03/24 2020/04/07 rogid:ZE4tXTFi7lUCcIbCL4KHzY3a6xM9606 rogid:wSsO6DP0LPkeh39DF/dAvEktuTE9606 rigid:Yhx0rOseaBytn3hdnMzCaibVOLg false - - - - psi-mi:"MI:0427"(Identification by mass spectrometry) psi-mi:"MI:0427"(Identification by mass spectrometry) uniprotkb:Q9H4B8 uniprotkb:Q9BY14 intact:EBI-20843342|ensembl:ENSP00000268793|uniprotkb:B3KQ48|uniprotkb:Q6PEZ5|uniprotkb:Q6UXE4 intact:EBI-12549378|ensembl:ENSP00000472769|uniprotkb:Q7L5R2|uniprotkb:Q9BPY7 psi-mi:dpep3_human(display_long)|uniprotkb:DPEP3(gene name)|psi-mi:DPEP3(display_short)|uniprotkb:UNQ834/PRO1772(orf name) psi-mi:tx101_human(display_long)|uniprotkb:TEX101(gene name)|psi-mi:TEX101(display_short)|uniprotkb:Cell surface receptor NYD-SP8(gene name synonym)|uniprotkb:SGRG(gene name synonym)|uniprotkb:Scleroderma-associated autoantigen(gene name synonym)|uniprotkb:Spermatogenesis-related gene protein(gene name synonym)|uniprotkb:UNQ867/PRO1884(orf name) psi-mi:"MI:0411"(enzyme linked immunosorbent assay) Schiza et al. (2018) imex:IM-28077|pubmed:30097533 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:2364"(proximity) psi-mi:"MI:0486"(UniProt) intact:EBI-25505750|imex:IM-28077-13 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000141096(gene)|ensembl:ENST00000268793(transcript)|go:"GO:0001669"(acrosomal vesicle)|go:"GO:0005886"(plasma membrane)|go:"GO:0016805"(dipeptidase activity)|go:"GO:0031225"(anchored component of membrane)|go:"GO:0046872"(metal ion binding)|go:"GO:0070573"(metallodipeptidase activity)|interpro:IPR000180(Peptidase M19, renal dipeptidase, active site)|interpro:IPR008257(Peptidase M19, renal dipeptidase)|interpro:IPR028531|interpro:IPR032466|rcsb pdb:6VGO|rcsb pdb:6VGR|reactome:R-HSA-2142691|reactome:R-HSA-5423646|reactome:R-HSA-9664535|refseq:NP_001123230.1|refseq:NP_071752.3 ensembl:ENSG00000131126(gene)|ensembl:ENST00000598265(transcript)|go:"GO:0001669"(acrosomal vesicle)|go:"GO:0002080"(acrosomal membrane)|go:"GO:0005576"(extracellular region)|go:"GO:0005886"(plasma membrane)|go:"GO:0007339"(binding of sperm to zona pellucida)|go:"GO:0009566"(fertilization)|go:"GO:0030317"(flagellated sperm motility)|go:"GO:0044853"(plasma membrane raft)|go:"GO:0046658"(anchored component of plasma membrane)|go:"GO:1901317"(regulation of flagellated sperm motility)|interpro:IPR016054(Ly-6 antigen / uPA receptor -like)|rcsb pdb:7BPR|reactome:R-HSA-163125|refseq:NP_001123483.1|refseq:NP_113639.4 - - - figure legend:Fig. 4A, Fig 6.|comment:Complex formation could be disrupted by anti-TEX101 antibody T4 raised against a distinct TEX101 epitope.|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-testis)|taxid:9606(Homo sapiens) - 2020/03/24 2020/04/07 rogid:wSsO6DP0LPkeh39DF/dAvEktuTE9606 rogid:ZE4tXTFi7lUCcIbCL4KHzY3a6xM9606 rigid:EW0wanTir8Vf6dOVIO9SzjajhLg false - - - - psi-mi:"MI:0421"(identification by antibody) psi-mi:"MI:0421"(identification by antibody) uniprotkb:Q9H4B8 uniprotkb:Q9BY14 intact:EBI-20843342|ensembl:ENSP00000268793|uniprotkb:B3KQ48|uniprotkb:Q6PEZ5|uniprotkb:Q6UXE4 intact:EBI-12549378|ensembl:ENSP00000472769|uniprotkb:Q7L5R2|uniprotkb:Q9BPY7 psi-mi:dpep3_human(display_long)|uniprotkb:DPEP3(gene name)|psi-mi:DPEP3(display_short)|uniprotkb:UNQ834/PRO1772(orf name) psi-mi:tx101_human(display_long)|uniprotkb:TEX101(gene name)|psi-mi:TEX101(display_short)|uniprotkb:Cell surface receptor NYD-SP8(gene name synonym)|uniprotkb:SGRG(gene name synonym)|uniprotkb:Scleroderma-associated autoantigen(gene name synonym)|uniprotkb:Spermatogenesis-related gene protein(gene name synonym)|uniprotkb:UNQ867/PRO1884(orf name) psi-mi:"MI:0411"(enzyme linked immunosorbent assay) Schiza et al. (2018) imex:IM-28077|pubmed:30097533 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:2364"(proximity) psi-mi:"MI:0486"(UniProt) intact:EBI-25505755|imex:IM-28077-15 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000141096(gene)|ensembl:ENST00000268793(transcript)|go:"GO:0001669"(acrosomal vesicle)|go:"GO:0005886"(plasma membrane)|go:"GO:0016805"(dipeptidase activity)|go:"GO:0031225"(anchored component of membrane)|go:"GO:0046872"(metal ion binding)|go:"GO:0070573"(metallodipeptidase activity)|interpro:IPR000180(Peptidase M19, renal dipeptidase, active site)|interpro:IPR008257(Peptidase M19, renal dipeptidase)|interpro:IPR028531|interpro:IPR032466|rcsb pdb:6VGO|rcsb pdb:6VGR|reactome:R-HSA-2142691|reactome:R-HSA-5423646|reactome:R-HSA-9664535|refseq:NP_001123230.1|refseq:NP_071752.3 ensembl:ENSG00000131126(gene)|ensembl:ENST00000598265(transcript)|go:"GO:0001669"(acrosomal vesicle)|go:"GO:0002080"(acrosomal membrane)|go:"GO:0005576"(extracellular region)|go:"GO:0005886"(plasma membrane)|go:"GO:0007339"(binding of sperm to zona pellucida)|go:"GO:0009566"(fertilization)|go:"GO:0030317"(flagellated sperm motility)|go:"GO:0044853"(plasma membrane raft)|go:"GO:0046658"(anchored component of plasma membrane)|go:"GO:1901317"(regulation of flagellated sperm motility)|interpro:IPR016054(Ly-6 antigen / uPA receptor -like)|rcsb pdb:7BPR|reactome:R-HSA-163125|refseq:NP_001123483.1|refseq:NP_113639.4 - - - figure legend:Fig. 4A|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-testis)|taxid:9606(Homo sapiens) - 2020/03/24 2020/04/07 rogid:wSsO6DP0LPkeh39DF/dAvEktuTE9606 rogid:ZE4tXTFi7lUCcIbCL4KHzY3a6xM9606 rigid:EW0wanTir8Vf6dOVIO9SzjajhLg false - - - - psi-mi:"MI:0421"(identification by antibody) psi-mi:"MI:0421"(identification by antibody) uniprotkb:Q9H4B8 uniprotkb:Q9BY14 intact:EBI-20843342|ensembl:ENSP00000268793|uniprotkb:B3KQ48|uniprotkb:Q6PEZ5|uniprotkb:Q6UXE4 intact:EBI-12549378|ensembl:ENSP00000472769|uniprotkb:Q7L5R2|uniprotkb:Q9BPY7 psi-mi:dpep3_human(display_long)|uniprotkb:DPEP3(gene name)|psi-mi:DPEP3(display_short)|uniprotkb:UNQ834/PRO1772(orf name) psi-mi:tx101_human(display_long)|uniprotkb:TEX101(gene name)|psi-mi:TEX101(display_short)|uniprotkb:Cell surface receptor NYD-SP8(gene name synonym)|uniprotkb:SGRG(gene name synonym)|uniprotkb:Scleroderma-associated autoantigen(gene name synonym)|uniprotkb:Spermatogenesis-related gene protein(gene name synonym)|uniprotkb:UNQ867/PRO1884(orf name) psi-mi:"MI:0411"(enzyme linked immunosorbent assay) Schiza et al. (2018) imex:IM-28077|pubmed:30097533 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:2364"(proximity) psi-mi:"MI:0486"(UniProt) intact:EBI-25505771|imex:IM-28077-19 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000141096(gene)|ensembl:ENST00000268793(transcript)|go:"GO:0001669"(acrosomal vesicle)|go:"GO:0005886"(plasma membrane)|go:"GO:0016805"(dipeptidase activity)|go:"GO:0031225"(anchored component of membrane)|go:"GO:0046872"(metal ion binding)|go:"GO:0070573"(metallodipeptidase activity)|interpro:IPR000180(Peptidase M19, renal dipeptidase, active site)|interpro:IPR008257(Peptidase M19, renal dipeptidase)|interpro:IPR028531|interpro:IPR032466|rcsb pdb:6VGO|rcsb pdb:6VGR|reactome:R-HSA-2142691|reactome:R-HSA-5423646|reactome:R-HSA-9664535|refseq:NP_001123230.1|refseq:NP_071752.3 ensembl:ENSG00000131126(gene)|ensembl:ENST00000598265(transcript)|go:"GO:0001669"(acrosomal vesicle)|go:"GO:0002080"(acrosomal membrane)|go:"GO:0005576"(extracellular region)|go:"GO:0005886"(plasma membrane)|go:"GO:0007339"(binding of sperm to zona pellucida)|go:"GO:0009566"(fertilization)|go:"GO:0030317"(flagellated sperm motility)|go:"GO:0044853"(plasma membrane raft)|go:"GO:0046658"(anchored component of plasma membrane)|go:"GO:1901317"(regulation of flagellated sperm motility)|interpro:IPR016054(Ly-6 antigen / uPA receptor -like)|rcsb pdb:7BPR|reactome:R-HSA-163125|refseq:NP_001123483.1|refseq:NP_113639.4 - - - figure legend:Fig. 4B|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-spermatozoa)|taxid:9606(Homo sapiens) - 2020/03/24 2020/04/07 rogid:wSsO6DP0LPkeh39DF/dAvEktuTE9606 rogid:ZE4tXTFi7lUCcIbCL4KHzY3a6xM9606 rigid:EW0wanTir8Vf6dOVIO9SzjajhLg false - - - - psi-mi:"MI:0421"(identification by antibody) psi-mi:"MI:0421"(identification by antibody) uniprotkb:Q9H4B8 uniprotkb:Q9BY14 intact:EBI-20843342|ensembl:ENSP00000268793|uniprotkb:B3KQ48|uniprotkb:Q6PEZ5|uniprotkb:Q6UXE4 intact:EBI-12549378|ensembl:ENSP00000472769|uniprotkb:Q7L5R2|uniprotkb:Q9BPY7 psi-mi:dpep3_human(display_long)|uniprotkb:DPEP3(gene name)|psi-mi:DPEP3(display_short)|uniprotkb:UNQ834/PRO1772(orf name) psi-mi:tx101_human(display_long)|uniprotkb:TEX101(gene name)|psi-mi:TEX101(display_short)|uniprotkb:Cell surface receptor NYD-SP8(gene name synonym)|uniprotkb:SGRG(gene name synonym)|uniprotkb:Scleroderma-associated autoantigen(gene name synonym)|uniprotkb:Spermatogenesis-related gene protein(gene name synonym)|uniprotkb:UNQ867/PRO1884(orf name) psi-mi:"MI:0411"(enzyme linked immunosorbent assay) Schiza et al. (2018) imex:IM-28077|pubmed:30097533 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:2364"(proximity) psi-mi:"MI:0486"(UniProt) intact:EBI-25505767|imex:IM-28077-17 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000141096(gene)|ensembl:ENST00000268793(transcript)|go:"GO:0001669"(acrosomal vesicle)|go:"GO:0005886"(plasma membrane)|go:"GO:0016805"(dipeptidase activity)|go:"GO:0031225"(anchored component of membrane)|go:"GO:0046872"(metal ion binding)|go:"GO:0070573"(metallodipeptidase activity)|interpro:IPR000180(Peptidase M19, renal dipeptidase, active site)|interpro:IPR008257(Peptidase M19, renal dipeptidase)|interpro:IPR028531|interpro:IPR032466|rcsb pdb:6VGO|rcsb pdb:6VGR|reactome:R-HSA-2142691|reactome:R-HSA-5423646|reactome:R-HSA-9664535|refseq:NP_001123230.1|refseq:NP_071752.3 ensembl:ENSG00000131126(gene)|ensembl:ENST00000598265(transcript)|go:"GO:0001669"(acrosomal vesicle)|go:"GO:0002080"(acrosomal membrane)|go:"GO:0005576"(extracellular region)|go:"GO:0005886"(plasma membrane)|go:"GO:0007339"(binding of sperm to zona pellucida)|go:"GO:0009566"(fertilization)|go:"GO:0030317"(flagellated sperm motility)|go:"GO:0044853"(plasma membrane raft)|go:"GO:0046658"(anchored component of plasma membrane)|go:"GO:1901317"(regulation of flagellated sperm motility)|interpro:IPR016054(Ly-6 antigen / uPA receptor -like)|rcsb pdb:7BPR|reactome:R-HSA-163125|refseq:NP_001123483.1|refseq:NP_113639.4 - - - figure legend:Fig. 4B|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-spermatozoa)|taxid:9606(Homo sapiens) - 2020/03/24 2020/04/07 rogid:wSsO6DP0LPkeh39DF/dAvEktuTE9606 rogid:ZE4tXTFi7lUCcIbCL4KHzY3a6xM9606 rigid:EW0wanTir8Vf6dOVIO9SzjajhLg false - - - - psi-mi:"MI:0421"(identification by antibody) psi-mi:"MI:0421"(identification by antibody)