#ID(s) interactor A ID(s) interactor B Alt. ID(s) interactor A Alt. ID(s) interactor B Alias(es) interactor A Alias(es) interactor B Interaction detection method(s) Publication 1st author(s) Publication Identifier(s) Taxid interactor A Taxid interactor B Interaction type(s) Source database(s) Interaction identifier(s) Confidence value(s) Expansion method(s) Biological role(s) interactor A Biological role(s) interactor B Experimental role(s) interactor A Experimental role(s) interactor B Type(s) interactor A Type(s) interactor B Xref(s) interactor A Xref(s) interactor B Interaction Xref(s) Annotation(s) interactor A Annotation(s) interactor B Interaction annotation(s) Host organism(s) Interaction parameter(s) Creation date Update date Checksum(s) interactor A Checksum(s) interactor B Interaction Checksum(s) Negative Feature(s) interactor A Feature(s) interactor B Stoichiometry(s) interactor A Stoichiometry(s) interactor B Identification method participant A Identification method participant B uniprotkb:P0ABE7 intact:EBI-26956493 intact:EBI-1120486|uniprotkb:P00192|uniprotkb:P76805|uniprotkb:Q8XCE3 - psi-mi:c562_ecolx(display_long)|uniprotkb:cybC(gene name)|psi-mi:cybC(display_short) psi-mi:fab_hc_synthetic(display_short)|psi-mi:EBI-26956493(display_long) psi-mi:"MI:0410"(3D electron microscopy) Kang et al. (2018) pubmed:29899450|imex:IM-28379 taxid:562(ecolx)|taxid:562(Escherichia coli) taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0465"(DIP) intact:EBI-25681738|wwpdb:6CMO|emdb:EMD-7517|imex:IM-28379-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) rcsb pdb:3M4C|rcsb pdb:3M79|rcsb pdb:3NMI|rcsb pdb:3NMJ|rcsb pdb:3NMK|rcsb pdb:3TOL|rcsb pdb:3TOM|rcsb pdb:4IAQ|rcsb pdb:3U8P|rcsb pdb:4PXZ|rcsb pdb:4PY0|rcsb pdb:5DHG|rcsb pdb:4RWA|rcsb pdb:4RWD|rcsb pdb:4U9D|rcsb pdb:4L6R|rcsb pdb:4N6H|rcsb pdb:4NC3|rcsb pdb:5YO4|rcsb pdb:5YO5|rcsb pdb:5YO6|rcsb pdb:4QIM|rcsb pdb:4QIN|interpro:IPR009155(Cytochrome b562)|interpro:IPR010980(Cytochrome c and b562)|rcsb pdb:1APC|rcsb pdb:1LM3|rcsb pdb:1M6T|rcsb pdb:1QPU|rcsb pdb:1QQ3|rcsb pdb:256B|rcsb pdb:2BC5|rcsb pdb:2QLA|rcsb pdb:3C62|rcsb pdb:3C63|rcsb pdb:3DE8|rcsb pdb:3DE9|rcsb pdb:3FOO|rcsb pdb:3FOP|rcsb pdb:3HNI|rcsb pdb:3HNJ|rcsb pdb:4Z34|rcsb pdb:4Z35|rcsb pdb:4Z36|rcsb pdb:3HNK|rcsb pdb:3HNL|rcsb pdb:3IQ5|rcsb pdb:3IQ6|rcsb pdb:3L1M|rcsb pdb:3M15|rcsb pdb:3M4B|rcsb pdb:6BQG|rcsb pdb:6BQH|rcsb pdb:6AK3|rcsb pdb:6G7O|rcsb pdb:6IIU|rcsb pdb:6IIV|go:"GO:0005506"(iron ion binding)|go:"GO:0009055"(electron transfer activity)|go:"GO:0020037"(heme binding)|go:"GO:0042597"(periplasmic space)|rcsb pdb:6LPJ|rcsb pdb:6LPK|rcsb pdb:6LPL|rcsb pdb:6WQA|rcsb pdb:7DFP|rcsb pdb:6ME6|rcsb pdb:6ME7|rcsb pdb:6ME8|rcsb pdb:6ME9|rcsb pdb:6MH8|rcsb pdb:4ZUD|rcsb pdb:5AWI|rcsb pdb:5YO3|rcsb pdb:6DY4|rcsb pdb:6DY6|rcsb pdb:6DY8|rcsb pdb:6DYB|rcsb pdb:6DYC|rcsb pdb:6DYD|rcsb pdb:6DYE|rcsb pdb:6DYF|rcsb pdb:6DYG|rcsb pdb:6DYH|rcsb pdb:6DYI|rcsb pdb:6DYJ|rcsb pdb:6DYK|rcsb pdb:6DYL|rcsb pdb:6M97|rcsb pdb:6M98|rcsb pdb:5UEN|rcsb pdb:4EIY|rcsb pdb:4IAR|rcsb pdb:4IB4|rcsb pdb:4JE9|rcsb pdb:4JEA|rcsb pdb:4JEB|rcsb pdb:4YAY|rcsb pdb:4EA3|rcsb pdb:7JVR|rcsb pdb:4JKV|rcsb pdb:6GT3|rcsb pdb:6S0Q|rcsb pdb:5WIU|rcsb pdb:5WIV|rcsb pdb:6LW5|rcsb pdb:6OS0|rcsb pdb:6OS1|rcsb pdb:6OS2|rcsb pdb:6OT4|rcsb pdb:6OT7|rcsb pdb:6OT8|rcsb pdb:6OT9|rcsb pdb:6OVH|rcsb pdb:4O9R|rcsb pdb:5IU4|rcsb pdb:5IU7|rcsb pdb:5IU8|rcsb pdb:5IUA|rcsb pdb:5IUB|rcsb pdb:5K2A|rcsb pdb:5K2B|rcsb pdb:5L7D|rcsb pdb:5L7I|rcsb pdb:7ARO|rcsb pdb:7CMU|rcsb pdb:7CMV|rcsb pdb:7E2X|rcsb pdb:7E2Y|rcsb pdb:7E2Z|rcsb pdb:7E32|rcsb pdb:7E33|rcsb pdb:7KOO|rcsb pdb:7KOQ|rcsb pdb:7KOX|rcsb pdb:4NTJ|rcsb pdb:4OR2|rcsb pdb:6DO1|rcsb pdb:6CC4|rcsb pdb:6CMO|rcsb pdb:5BU7|rcsb pdb:4U9E|refseq:WP_001232240.1|rcsb pdb:6C1Q|rcsb pdb:6C1R|rcsb pdb:6D32|rcsb pdb:6D35|rcsb pdb:6UR8|rcsb pdb:6USF|rcsb pdb:5JTB|rcsb pdb:5UVI|rcsb pdb:5K2C|rcsb pdb:5K2D|rcsb pdb:5L31|rcsb pdb:5L32|rcsb pdb:5TVN|rcsb pdb:5OLG|rcsb pdb:5OLH|rcsb pdb:5OLO|rcsb pdb:5OLV|rcsb pdb:5OLZ|rcsb pdb:5OM1|rcsb pdb:5OM4|rcsb pdb:5VRA|rcsb pdb:5XZI|rcsb pdb:5XZJ|rcsb pdb:6AQF|rcsb pdb:6B73|rcsb pdb:5UIG|rcsb pdb:5UNF|rcsb pdb:5UNG|rcsb pdb:5UNH|rcsb pdb:5NDD|rcsb pdb:5NDZ|rcsb pdb:5NJ6|rcsb pdb:5DHH|rcsb pdb:5MZJ|rcsb pdb:5MZP|rcsb pdb:5N2R|rcsb pdb:5N2S|rcsb pdb:5TUD|rcsb pdb:5NLX|rcsb pdb:5NM2|rcsb pdb:5NM4|rcsb pdb:5YM7|rcsb pdb:5XJM|rcsb pdb:6DHY|rcsb pdb:6DHZ|rcsb pdb:6DRX|rcsb pdb:6DRY|rcsb pdb:6DRZ|rcsb pdb:6DS0|rcsb pdb:6A93|rcsb pdb:6A94|rcsb pdb:6CBV|rcsb pdb:6AI5|rcsb pdb:6JZH|rcsb pdb:6PS7|rcsb pdb:6RZ4|rcsb pdb:6RZ5|rcsb pdb:6IQL|rcsb pdb:6JOD|rcsb pdb:6RZ6|rcsb pdb:6RZ7|rcsb pdb:6RZ8|rcsb pdb:6RZ9|rcsb pdb:6KO5|rcsb pdb:6WW2|rcsb pdb:6WWZ|rcsb pdb:7BW0|rcsb pdb:7C61|rcsb pdb:7C6A|rcsb pdb:6WGT|rcsb pdb:6WH4|rcsb pdb:6WHA|rcsb pdb:6WYU|rcsb pdb:6WZ0|rcsb pdb:6WZ1|rcsb pdb:6WZ2|rcsb pdb:6WZ3|rcsb pdb:6WZ7|rcsb pdb:6WZA|rcsb pdb:6WZC|rcsb pdb:6X7E|rcsb pdb:6X8X|rcsb pdb:6ZDR|rcsb pdb:6ZDV pdbe:6cmo(see-also) - - - figure legend:Fig 2, Extended Data Fig 2, Extended Data Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2020/06/17 2021/04/19 rogid:O9HPXjm/UQpqt+WPfwjDOEx8+m4562 rogid:kHdKFIFlPHbrvQ6sMkg60vnYRcM-2 rigid:byUWCYFrBR1Dh68SItQ8WMUKU8E false - - 1 - psi-mi:"MI:0396"(predetermined participant)|psi-mi:"MI:2287"(identification by structure determination) psi-mi:"MI:0661"(experimental participant identification) uniprotkb:P0ABE7 intact:EBI-26956490 intact:EBI-1120486|uniprotkb:P00192|uniprotkb:P76805|uniprotkb:Q8XCE3 - psi-mi:c562_ecolx(display_long)|uniprotkb:cybC(gene name)|psi-mi:cybC(display_short) psi-mi:fab_lc_synthetic(display_short)|psi-mi:EBI-26956490(display_long) psi-mi:"MI:0410"(3D electron microscopy) Kang et al. (2018) pubmed:29899450|imex:IM-28379 taxid:562(ecolx)|taxid:562(Escherichia coli) taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0465"(DIP) intact:EBI-25681738|wwpdb:6CMO|emdb:EMD-7517|imex:IM-28379-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) rcsb pdb:3M4C|rcsb pdb:3M79|rcsb pdb:3NMI|rcsb pdb:3NMJ|rcsb pdb:3NMK|rcsb pdb:3TOL|rcsb pdb:3TOM|rcsb pdb:4IAQ|rcsb pdb:3U8P|rcsb pdb:4PXZ|rcsb pdb:4PY0|rcsb pdb:5DHG|rcsb pdb:4RWA|rcsb pdb:4RWD|rcsb pdb:4U9D|rcsb pdb:4L6R|rcsb pdb:4N6H|rcsb pdb:4NC3|rcsb pdb:5YO4|rcsb pdb:5YO5|rcsb pdb:5YO6|rcsb pdb:4QIM|rcsb pdb:4QIN|interpro:IPR009155(Cytochrome b562)|interpro:IPR010980(Cytochrome c and b562)|rcsb pdb:1APC|rcsb pdb:1LM3|rcsb pdb:1M6T|rcsb pdb:1QPU|rcsb pdb:1QQ3|rcsb pdb:256B|rcsb pdb:2BC5|rcsb pdb:2QLA|rcsb pdb:3C62|rcsb pdb:3C63|rcsb pdb:3DE8|rcsb pdb:3DE9|rcsb pdb:3FOO|rcsb pdb:3FOP|rcsb pdb:3HNI|rcsb pdb:3HNJ|rcsb pdb:4Z34|rcsb pdb:4Z35|rcsb pdb:4Z36|rcsb pdb:3HNK|rcsb pdb:3HNL|rcsb pdb:3IQ5|rcsb pdb:3IQ6|rcsb pdb:3L1M|rcsb pdb:3M15|rcsb pdb:3M4B|rcsb pdb:6BQG|rcsb pdb:6BQH|rcsb pdb:6AK3|rcsb pdb:6G7O|rcsb pdb:6IIU|rcsb pdb:6IIV|go:"GO:0005506"(iron ion binding)|go:"GO:0009055"(electron transfer activity)|go:"GO:0020037"(heme binding)|go:"GO:0042597"(periplasmic space)|rcsb pdb:6LPJ|rcsb pdb:6LPK|rcsb pdb:6LPL|rcsb pdb:6WQA|rcsb pdb:7DFP|rcsb pdb:6ME6|rcsb pdb:6ME7|rcsb pdb:6ME8|rcsb pdb:6ME9|rcsb pdb:6MH8|rcsb pdb:4ZUD|rcsb pdb:5AWI|rcsb pdb:5YO3|rcsb pdb:6DY4|rcsb pdb:6DY6|rcsb pdb:6DY8|rcsb pdb:6DYB|rcsb pdb:6DYC|rcsb pdb:6DYD|rcsb pdb:6DYE|rcsb pdb:6DYF|rcsb pdb:6DYG|rcsb pdb:6DYH|rcsb pdb:6DYI|rcsb pdb:6DYJ|rcsb pdb:6DYK|rcsb pdb:6DYL|rcsb pdb:6M97|rcsb pdb:6M98|rcsb pdb:5UEN|rcsb pdb:4EIY|rcsb pdb:4IAR|rcsb pdb:4IB4|rcsb pdb:4JE9|rcsb pdb:4JEA|rcsb pdb:4JEB|rcsb pdb:4YAY|rcsb pdb:4EA3|rcsb pdb:7JVR|rcsb pdb:4JKV|rcsb pdb:6GT3|rcsb pdb:6S0Q|rcsb pdb:5WIU|rcsb pdb:5WIV|rcsb pdb:6LW5|rcsb pdb:6OS0|rcsb pdb:6OS1|rcsb pdb:6OS2|rcsb pdb:6OT4|rcsb pdb:6OT7|rcsb pdb:6OT8|rcsb pdb:6OT9|rcsb pdb:6OVH|rcsb pdb:4O9R|rcsb pdb:5IU4|rcsb pdb:5IU7|rcsb pdb:5IU8|rcsb pdb:5IUA|rcsb pdb:5IUB|rcsb pdb:5K2A|rcsb pdb:5K2B|rcsb pdb:5L7D|rcsb pdb:5L7I|rcsb pdb:7ARO|rcsb pdb:7CMU|rcsb pdb:7CMV|rcsb pdb:7E2X|rcsb pdb:7E2Y|rcsb pdb:7E2Z|rcsb pdb:7E32|rcsb pdb:7E33|rcsb pdb:7KOO|rcsb pdb:7KOQ|rcsb pdb:7KOX|rcsb pdb:4NTJ|rcsb pdb:4OR2|rcsb pdb:6DO1|rcsb pdb:6CC4|rcsb pdb:6CMO|rcsb pdb:5BU7|rcsb pdb:4U9E|refseq:WP_001232240.1|rcsb pdb:6C1Q|rcsb pdb:6C1R|rcsb pdb:6D32|rcsb pdb:6D35|rcsb pdb:6UR8|rcsb pdb:6USF|rcsb pdb:5JTB|rcsb pdb:5UVI|rcsb pdb:5K2C|rcsb pdb:5K2D|rcsb pdb:5L31|rcsb pdb:5L32|rcsb pdb:5TVN|rcsb pdb:5OLG|rcsb pdb:5OLH|rcsb pdb:5OLO|rcsb pdb:5OLV|rcsb pdb:5OLZ|rcsb pdb:5OM1|rcsb pdb:5OM4|rcsb pdb:5VRA|rcsb pdb:5XZI|rcsb pdb:5XZJ|rcsb pdb:6AQF|rcsb pdb:6B73|rcsb pdb:5UIG|rcsb pdb:5UNF|rcsb pdb:5UNG|rcsb pdb:5UNH|rcsb pdb:5NDD|rcsb pdb:5NDZ|rcsb pdb:5NJ6|rcsb pdb:5DHH|rcsb pdb:5MZJ|rcsb pdb:5MZP|rcsb pdb:5N2R|rcsb pdb:5N2S|rcsb pdb:5TUD|rcsb pdb:5NLX|rcsb pdb:5NM2|rcsb pdb:5NM4|rcsb pdb:5YM7|rcsb pdb:5XJM|rcsb pdb:6DHY|rcsb pdb:6DHZ|rcsb pdb:6DRX|rcsb pdb:6DRY|rcsb pdb:6DRZ|rcsb pdb:6DS0|rcsb pdb:6A93|rcsb pdb:6A94|rcsb pdb:6CBV|rcsb pdb:6AI5|rcsb pdb:6JZH|rcsb pdb:6PS7|rcsb pdb:6RZ4|rcsb pdb:6RZ5|rcsb pdb:6IQL|rcsb pdb:6JOD|rcsb pdb:6RZ6|rcsb pdb:6RZ7|rcsb pdb:6RZ8|rcsb pdb:6RZ9|rcsb pdb:6KO5|rcsb pdb:6WW2|rcsb pdb:6WWZ|rcsb pdb:7BW0|rcsb pdb:7C61|rcsb pdb:7C6A|rcsb pdb:6WGT|rcsb pdb:6WH4|rcsb pdb:6WHA|rcsb pdb:6WYU|rcsb pdb:6WZ0|rcsb pdb:6WZ1|rcsb pdb:6WZ2|rcsb pdb:6WZ3|rcsb pdb:6WZ7|rcsb pdb:6WZA|rcsb pdb:6WZC|rcsb pdb:6X7E|rcsb pdb:6X8X|rcsb pdb:6ZDR|rcsb pdb:6ZDV pdbe:6cmo(see-also) - - - figure legend:Fig 2, Extended Data Fig 2, Extended Data Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2020/06/17 2021/04/19 rogid:O9HPXjm/UQpqt+WPfwjDOEx8+m4562 rogid:FFTkG2YdM9f48AtYDB+EHMKETWQ-2 rigid:byUWCYFrBR1Dh68SItQ8WMUKU8E false - - 1 - psi-mi:"MI:0396"(predetermined participant)|psi-mi:"MI:2287"(identification by structure determination) psi-mi:"MI:0661"(experimental participant identification) uniprotkb:P0ABE7 uniprotkb:P54311 intact:EBI-1120486|uniprotkb:P00192|uniprotkb:P76805|uniprotkb:Q8XCE3 intact:EBI-917779|uniprotkb:Q6Q8B1|uniprotkb:Q9QWG8|ensembl:ENSRNOP00000044340 psi-mi:c562_ecolx(display_long)|uniprotkb:cybC(gene name)|psi-mi:cybC(display_short) psi-mi:gbb1_rat(display_long)|uniprotkb:Transducin beta chain 1(gene name synonym)|uniprotkb:Gnb1(gene name)|psi-mi:Gnb1(display_short) psi-mi:"MI:0410"(3D electron microscopy) Kang et al. (2018) pubmed:29899450|imex:IM-28379 taxid:562(ecolx)|taxid:562(Escherichia coli) taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0465"(DIP) intact:EBI-25681738|wwpdb:6CMO|emdb:EMD-7517|imex:IM-28379-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) rcsb pdb:3M4C|rcsb pdb:3M79|rcsb pdb:3NMI|rcsb pdb:3NMJ|rcsb pdb:3NMK|rcsb pdb:3TOL|rcsb pdb:3TOM|rcsb pdb:4IAQ|rcsb pdb:3U8P|rcsb pdb:4PXZ|rcsb pdb:4PY0|rcsb pdb:5DHG|rcsb pdb:4RWA|rcsb pdb:4RWD|rcsb pdb:4U9D|rcsb pdb:4L6R|rcsb pdb:4N6H|rcsb pdb:4NC3|rcsb pdb:5YO4|rcsb pdb:5YO5|rcsb pdb:5YO6|rcsb pdb:4QIM|rcsb pdb:4QIN|interpro:IPR009155(Cytochrome b562)|interpro:IPR010980(Cytochrome c and b562)|rcsb pdb:1APC|rcsb pdb:1LM3|rcsb pdb:1M6T|rcsb pdb:1QPU|rcsb pdb:1QQ3|rcsb pdb:256B|rcsb pdb:2BC5|rcsb pdb:2QLA|rcsb pdb:3C62|rcsb pdb:3C63|rcsb pdb:3DE8|rcsb pdb:3DE9|rcsb pdb:3FOO|rcsb pdb:3FOP|rcsb pdb:3HNI|rcsb pdb:3HNJ|rcsb pdb:4Z34|rcsb pdb:4Z35|rcsb pdb:4Z36|rcsb pdb:3HNK|rcsb pdb:3HNL|rcsb pdb:3IQ5|rcsb pdb:3IQ6|rcsb pdb:3L1M|rcsb pdb:3M15|rcsb pdb:3M4B|rcsb pdb:6BQG|rcsb pdb:6BQH|rcsb pdb:6AK3|rcsb pdb:6G7O|rcsb pdb:6IIU|rcsb pdb:6IIV|go:"GO:0005506"(iron ion binding)|go:"GO:0009055"(electron transfer activity)|go:"GO:0020037"(heme binding)|go:"GO:0042597"(periplasmic space)|rcsb pdb:6LPJ|rcsb pdb:6LPK|rcsb pdb:6LPL|rcsb pdb:6WQA|rcsb pdb:7DFP|rcsb pdb:6ME6|rcsb pdb:6ME7|rcsb pdb:6ME8|rcsb pdb:6ME9|rcsb pdb:6MH8|rcsb pdb:4ZUD|rcsb pdb:5AWI|rcsb pdb:5YO3|rcsb pdb:6DY4|rcsb pdb:6DY6|rcsb pdb:6DY8|rcsb pdb:6DYB|rcsb pdb:6DYC|rcsb pdb:6DYD|rcsb pdb:6DYE|rcsb pdb:6DYF|rcsb pdb:6DYG|rcsb pdb:6DYH|rcsb pdb:6DYI|rcsb pdb:6DYJ|rcsb pdb:6DYK|rcsb pdb:6DYL|rcsb pdb:6M97|rcsb pdb:6M98|rcsb pdb:5UEN|rcsb pdb:4EIY|rcsb pdb:4IAR|rcsb pdb:4IB4|rcsb pdb:4JE9|rcsb pdb:4JEA|rcsb pdb:4JEB|rcsb pdb:4YAY|rcsb pdb:4EA3|rcsb pdb:7JVR|rcsb pdb:4JKV|rcsb pdb:6GT3|rcsb pdb:6S0Q|rcsb pdb:5WIU|rcsb pdb:5WIV|rcsb pdb:6LW5|rcsb pdb:6OS0|rcsb pdb:6OS1|rcsb pdb:6OS2|rcsb pdb:6OT4|rcsb pdb:6OT7|rcsb pdb:6OT8|rcsb pdb:6OT9|rcsb pdb:6OVH|rcsb pdb:4O9R|rcsb pdb:5IU4|rcsb pdb:5IU7|rcsb pdb:5IU8|rcsb pdb:5IUA|rcsb pdb:5IUB|rcsb pdb:5K2A|rcsb pdb:5K2B|rcsb pdb:5L7D|rcsb pdb:5L7I|rcsb pdb:7ARO|rcsb pdb:7CMU|rcsb pdb:7CMV|rcsb pdb:7E2X|rcsb pdb:7E2Y|rcsb pdb:7E2Z|rcsb pdb:7E32|rcsb pdb:7E33|rcsb pdb:7KOO|rcsb pdb:7KOQ|rcsb pdb:7KOX|rcsb pdb:4NTJ|rcsb pdb:4OR2|rcsb pdb:6DO1|rcsb pdb:6CC4|rcsb pdb:6CMO|rcsb pdb:5BU7|rcsb pdb:4U9E|refseq:WP_001232240.1|rcsb pdb:6C1Q|rcsb pdb:6C1R|rcsb pdb:6D32|rcsb pdb:6D35|rcsb pdb:6UR8|rcsb pdb:6USF|rcsb pdb:5JTB|rcsb pdb:5UVI|rcsb pdb:5K2C|rcsb pdb:5K2D|rcsb pdb:5L31|rcsb pdb:5L32|rcsb pdb:5TVN|rcsb pdb:5OLG|rcsb pdb:5OLH|rcsb pdb:5OLO|rcsb pdb:5OLV|rcsb pdb:5OLZ|rcsb pdb:5OM1|rcsb pdb:5OM4|rcsb pdb:5VRA|rcsb pdb:5XZI|rcsb pdb:5XZJ|rcsb pdb:6AQF|rcsb pdb:6B73|rcsb pdb:5UIG|rcsb pdb:5UNF|rcsb pdb:5UNG|rcsb pdb:5UNH|rcsb pdb:5NDD|rcsb pdb:5NDZ|rcsb pdb:5NJ6|rcsb pdb:5DHH|rcsb pdb:5MZJ|rcsb pdb:5MZP|rcsb pdb:5N2R|rcsb pdb:5N2S|rcsb pdb:5TUD|rcsb pdb:5NLX|rcsb pdb:5NM2|rcsb pdb:5NM4|rcsb pdb:5YM7|rcsb pdb:5XJM|rcsb pdb:6DHY|rcsb pdb:6DHZ|rcsb pdb:6DRX|rcsb pdb:6DRY|rcsb pdb:6DRZ|rcsb pdb:6DS0|rcsb pdb:6A93|rcsb pdb:6A94|rcsb pdb:6CBV|rcsb pdb:6AI5|rcsb pdb:6JZH|rcsb pdb:6PS7|rcsb pdb:6RZ4|rcsb pdb:6RZ5|rcsb pdb:6IQL|rcsb pdb:6JOD|rcsb pdb:6RZ6|rcsb pdb:6RZ7|rcsb pdb:6RZ8|rcsb pdb:6RZ9|rcsb pdb:6KO5|rcsb pdb:6WW2|rcsb pdb:6WWZ|rcsb pdb:7BW0|rcsb pdb:7C61|rcsb pdb:7C6A|rcsb pdb:6WGT|rcsb pdb:6WH4|rcsb pdb:6WHA|rcsb pdb:6WYU|rcsb pdb:6WZ0|rcsb pdb:6WZ1|rcsb pdb:6WZ2|rcsb pdb:6WZ3|rcsb pdb:6WZ7|rcsb pdb:6WZA|rcsb pdb:6WZC|rcsb pdb:6X7E|rcsb pdb:6X8X|rcsb pdb:6ZDR|rcsb pdb:6ZDV rgd:2718|refseq:NP_112249.2|go:"GO:0001750"(photoreceptor outer segment)|go:"GO:0001917"(photoreceptor inner segment)|go:"GO:0003924"(GTPase activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005834"(heterotrimeric G-protein complex)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0007200"(phospholipase C-activating G protein-coupled receptor signaling pathway)|go:"GO:0007204"(positive regulation of cytosolic calcium ion concentration)|go:"GO:0008283"(cell population proliferation)|go:"GO:0010659"(cardiac muscle cell apoptotic process)|go:"GO:0030425"(dendrite)|go:"GO:0030507"(spectrin binding)|go:"GO:0031682"(G-protein gamma-subunit binding)|go:"GO:0042622"(photoreceptor outer segment membrane)|go:"GO:0044297"(cell body)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0047391"(alkylglycerophosphoethanolamine phosphodiesterase activity)|go:"GO:0050909"(sensory perception of taste)|ensembl:ENSRNOT00000041789(transcript)|ensembl:ENSRNOG00000016638(gene)|refseq:XP_008762557.1|refseq:XP_006239579.1|refseq:XP_017448634.1|refseq:XP_017448635.1|refseq:XP_017448636.1|refseq:XP_017448637.1|refseq:XP_017448638.1|dip:DIP-37029N|go:"GO:0051020"(GTPase binding)|go:"GO:0060041"(retina development in camera-type eye)|go:"GO:0071456"(cellular response to hypoxia)|interpro:IPR001632(G-protein, beta subunit)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR016346(Guanine nucleotide-binding protein, beta subunit)|interpro:IPR019775|interpro:IPR020472|interpro:IPR036322|mint:P54311|rcsb pdb:3SN6|rcsb pdb:5TDH|rcsb pdb:5VAI|rcsb pdb:6CMO|rcsb pdb:6LPB|rcsb pdb:6NBF|rcsb pdb:6NBH|rcsb pdb:6NBI|rcsb pdb:6WWZ|rcsb pdb:7BW0|rcsb pdb:7CZ5|rcsb pdb:7D3S|rcsb pdb:7LJC|rcsb pdb:7LJD|rcsb pdb:7MBX|rcsb pdb:7MBY|reactome:R-RNO-1296041|reactome:R-RNO-202040|reactome:R-RNO-2485179|reactome:R-RNO-381676|reactome:R-RNO-381753|reactome:R-RNO-392170|reactome:R-RNO-392451|reactome:R-RNO-400042|reactome:R-RNO-4086398|reactome:R-RNO-416476|reactome:R-RNO-418594|reactome:R-RNO-418597|reactome:R-RNO-420092|reactome:R-RNO-428930|reactome:R-RNO-432040|reactome:R-RNO-456926|reactome:R-RNO-6814122|reactome:R-RNO-8964616|reactome:R-RNO-997272 - - - figure legend:Fig 2, Extended Data Fig 2, Extended Data Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2020/06/17 2021/04/19 rogid:O9HPXjm/UQpqt+WPfwjDOEx8+m4562 rogid:zP/G70MXiSQpzbyyWFTWrJFQENk10116 rigid:byUWCYFrBR1Dh68SItQ8WMUKU8E false - - 1 1 psi-mi:"MI:0396"(predetermined participant)|psi-mi:"MI:2287"(identification by structure determination) psi-mi:"MI:0396"(predetermined participant)|psi-mi:"MI:2287"(identification by structure determination) uniprotkb:P0ABE7 uniprotkb:P63212 intact:EBI-1120486|uniprotkb:P00192|uniprotkb:P76805|uniprotkb:Q8XCE3 intact:EBI-1036424|uniprotkb:P16874|uniprotkb:Q2KI31|uniprotkb:Q61013|uniprotkb:Q9TS47|ensembl:ENSBTAP00000003959 psi-mi:c562_ecolx(display_long)|uniprotkb:cybC(gene name)|psi-mi:cybC(display_short) psi-mi:gbg2_bovin(display_long)|uniprotkb:GNG2(gene name)|psi-mi:GNG2(display_short)|uniprotkb:G gamma-I(gene name synonym) psi-mi:"MI:0410"(3D electron microscopy) Kang et al. (2018) pubmed:29899450|imex:IM-28379 taxid:562(ecolx)|taxid:562(Escherichia coli) taxid:9913(bovin)|taxid:9913("Bos taurus (Bovine)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0465"(DIP) intact:EBI-25681738|wwpdb:6CMO|emdb:EMD-7517|imex:IM-28379-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) rcsb pdb:3M4C|rcsb pdb:3M79|rcsb pdb:3NMI|rcsb pdb:3NMJ|rcsb pdb:3NMK|rcsb pdb:3TOL|rcsb pdb:3TOM|rcsb pdb:4IAQ|rcsb pdb:3U8P|rcsb pdb:4PXZ|rcsb pdb:4PY0|rcsb pdb:5DHG|rcsb pdb:4RWA|rcsb pdb:4RWD|rcsb pdb:4U9D|rcsb pdb:4L6R|rcsb pdb:4N6H|rcsb pdb:4NC3|rcsb pdb:5YO4|rcsb pdb:5YO5|rcsb pdb:5YO6|rcsb pdb:4QIM|rcsb pdb:4QIN|interpro:IPR009155(Cytochrome b562)|interpro:IPR010980(Cytochrome c and b562)|rcsb pdb:1APC|rcsb pdb:1LM3|rcsb pdb:1M6T|rcsb pdb:1QPU|rcsb pdb:1QQ3|rcsb pdb:256B|rcsb pdb:2BC5|rcsb pdb:2QLA|rcsb pdb:3C62|rcsb pdb:3C63|rcsb pdb:3DE8|rcsb pdb:3DE9|rcsb pdb:3FOO|rcsb pdb:3FOP|rcsb pdb:3HNI|rcsb pdb:3HNJ|rcsb pdb:4Z34|rcsb pdb:4Z35|rcsb pdb:4Z36|rcsb pdb:3HNK|rcsb pdb:3HNL|rcsb pdb:3IQ5|rcsb pdb:3IQ6|rcsb pdb:3L1M|rcsb pdb:3M15|rcsb pdb:3M4B|rcsb pdb:6BQG|rcsb pdb:6BQH|rcsb pdb:6AK3|rcsb pdb:6G7O|rcsb pdb:6IIU|rcsb pdb:6IIV|go:"GO:0005506"(iron ion binding)|go:"GO:0009055"(electron transfer activity)|go:"GO:0020037"(heme binding)|go:"GO:0042597"(periplasmic space)|rcsb pdb:6LPJ|rcsb pdb:6LPK|rcsb pdb:6LPL|rcsb pdb:6WQA|rcsb pdb:7DFP|rcsb pdb:6ME6|rcsb pdb:6ME7|rcsb pdb:6ME8|rcsb pdb:6ME9|rcsb pdb:6MH8|rcsb pdb:4ZUD|rcsb pdb:5AWI|rcsb pdb:5YO3|rcsb pdb:6DY4|rcsb pdb:6DY6|rcsb pdb:6DY8|rcsb pdb:6DYB|rcsb pdb:6DYC|rcsb pdb:6DYD|rcsb pdb:6DYE|rcsb pdb:6DYF|rcsb pdb:6DYG|rcsb pdb:6DYH|rcsb pdb:6DYI|rcsb pdb:6DYJ|rcsb pdb:6DYK|rcsb pdb:6DYL|rcsb pdb:6M97|rcsb pdb:6M98|rcsb pdb:5UEN|rcsb pdb:4EIY|rcsb pdb:4IAR|rcsb pdb:4IB4|rcsb pdb:4JE9|rcsb pdb:4JEA|rcsb pdb:4JEB|rcsb pdb:4YAY|rcsb pdb:4EA3|rcsb pdb:7JVR|rcsb pdb:4JKV|rcsb pdb:6GT3|rcsb pdb:6S0Q|rcsb pdb:5WIU|rcsb pdb:5WIV|rcsb pdb:6LW5|rcsb pdb:6OS0|rcsb pdb:6OS1|rcsb pdb:6OS2|rcsb pdb:6OT4|rcsb pdb:6OT7|rcsb pdb:6OT8|rcsb pdb:6OT9|rcsb pdb:6OVH|rcsb pdb:4O9R|rcsb pdb:5IU4|rcsb pdb:5IU7|rcsb pdb:5IU8|rcsb pdb:5IUA|rcsb pdb:5IUB|rcsb pdb:5K2A|rcsb pdb:5K2B|rcsb pdb:5L7D|rcsb pdb:5L7I|rcsb pdb:7ARO|rcsb pdb:7CMU|rcsb pdb:7CMV|rcsb pdb:7E2X|rcsb pdb:7E2Y|rcsb pdb:7E2Z|rcsb pdb:7E32|rcsb pdb:7E33|rcsb pdb:7KOO|rcsb pdb:7KOQ|rcsb pdb:7KOX|rcsb pdb:4NTJ|rcsb pdb:4OR2|rcsb pdb:6DO1|rcsb pdb:6CC4|rcsb pdb:6CMO|rcsb pdb:5BU7|rcsb pdb:4U9E|refseq:WP_001232240.1|rcsb pdb:6C1Q|rcsb pdb:6C1R|rcsb pdb:6D32|rcsb pdb:6D35|rcsb pdb:6UR8|rcsb pdb:6USF|rcsb pdb:5JTB|rcsb pdb:5UVI|rcsb pdb:5K2C|rcsb pdb:5K2D|rcsb pdb:5L31|rcsb pdb:5L32|rcsb pdb:5TVN|rcsb pdb:5OLG|rcsb pdb:5OLH|rcsb pdb:5OLO|rcsb pdb:5OLV|rcsb pdb:5OLZ|rcsb pdb:5OM1|rcsb pdb:5OM4|rcsb pdb:5VRA|rcsb pdb:5XZI|rcsb pdb:5XZJ|rcsb pdb:6AQF|rcsb pdb:6B73|rcsb pdb:5UIG|rcsb pdb:5UNF|rcsb pdb:5UNG|rcsb pdb:5UNH|rcsb pdb:5NDD|rcsb pdb:5NDZ|rcsb pdb:5NJ6|rcsb pdb:5DHH|rcsb pdb:5MZJ|rcsb pdb:5MZP|rcsb pdb:5N2R|rcsb pdb:5N2S|rcsb pdb:5TUD|rcsb pdb:5NLX|rcsb pdb:5NM2|rcsb pdb:5NM4|rcsb pdb:5YM7|rcsb pdb:5XJM|rcsb pdb:6DHY|rcsb pdb:6DHZ|rcsb pdb:6DRX|rcsb pdb:6DRY|rcsb pdb:6DRZ|rcsb pdb:6DS0|rcsb pdb:6A93|rcsb pdb:6A94|rcsb pdb:6CBV|rcsb pdb:6AI5|rcsb pdb:6JZH|rcsb pdb:6PS7|rcsb pdb:6RZ4|rcsb pdb:6RZ5|rcsb pdb:6IQL|rcsb pdb:6JOD|rcsb pdb:6RZ6|rcsb pdb:6RZ7|rcsb pdb:6RZ8|rcsb pdb:6RZ9|rcsb pdb:6KO5|rcsb pdb:6WW2|rcsb pdb:6WWZ|rcsb pdb:7BW0|rcsb pdb:7C61|rcsb pdb:7C6A|rcsb pdb:6WGT|rcsb pdb:6WH4|rcsb pdb:6WHA|rcsb pdb:6WYU|rcsb pdb:6WZ0|rcsb pdb:6WZ1|rcsb pdb:6WZ2|rcsb pdb:6WZ3|rcsb pdb:6WZ7|rcsb pdb:6WZA|rcsb pdb:6WZC|rcsb pdb:6X7E|rcsb pdb:6X8X|rcsb pdb:6ZDR|rcsb pdb:6ZDV refseq:NP_776497.1|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0007191"(adenylate cyclase-activating dopamine receptor signaling pathway)|go:"GO:0016020"(membrane)|go:"GO:0031680"(G-protein beta/gamma-subunit complex)|go:"GO:0031681"(G-protein beta-subunit binding)|go:"GO:0071380"(cellular response to prostaglandin E stimulus)|go:"GO:0071870"(cellular response to catecholamine stimulus)|interpro:IPR001770(G-protein, gamma subunit)|interpro:IPR015898(G-protein, gamma-like subunit)|interpro:IPR036284|rcsb pdb:1GG2|rcsb pdb:1GP2|rcsb pdb:1OMW|rcsb pdb:1XHM|rcsb pdb:2BCJ|rcsb pdb:3AH8|rcsb pdb:3CIK|rcsb pdb:3KRW|rcsb pdb:3KRX|rcsb pdb:3SN6|rcsb pdb:3UZS|rcsb pdb:3V5W|rcsb pdb:4MK0|rcsb pdb:4PNK|rcsb pdb:5TDH|rcsb pdb:5VAI|rcsb pdb:5WG3|rcsb pdb:5WG4|rcsb pdb:5WG5|rcsb pdb:6C2Y|rcsb pdb:6CMO|rcsb pdb:6LPB|rcsb pdb:6NBF|rcsb pdb:6NBH|rcsb pdb:6NBI|rcsb pdb:6PCV|rcsb pdb:6U7C|rcsb pdb:7BW0|rcsb pdb:7BZ2|rcsb pdb:7CZ5|rcsb pdb:7D3S|rcsb pdb:7D68|rcsb pdb:7DHI|rcsb pdb:7DHR|rcsb pdb:7JJO|rcsb pdb:3PSC|rcsb pdb:3PVU|rcsb pdb:3PVW|rcsb pdb:7LJC|rcsb pdb:7LJD|reactome:R-BTA-392170|reactome:R-BTA-416476|reactome:R-BTA-418594|reactome:R-BTA-418597|reactome:R-BTA-428930|reactome:R-BTA-456926|reactome:R-BTA-6814122|reactome:R-BTA-392451|ensembl:ENSBTAG00000003043(gene)|ensembl:ENSBTAT00000003959(transcript)|go:"GO:0003924"(GTPase activity)|go:"GO:0005834"(heterotrimeric G-protein complex)|refseq:XP_005211711.1|refseq:XP_010807541.1|dip:DIP-586N - - - figure legend:Fig 2, Extended Data Fig 2, Extended Data Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2020/06/17 2021/04/19 rogid:O9HPXjm/UQpqt+WPfwjDOEx8+m4562 rogid:8asTjDtSU6sCPSMwcXMbV340Rt49913 rigid:byUWCYFrBR1Dh68SItQ8WMUKU8E false - his tag:n-n|maltose binding protein tag:n-n 1 1 psi-mi:"MI:0396"(predetermined participant)|psi-mi:"MI:2287"(identification by structure determination) psi-mi:"MI:0396"(predetermined participant)|psi-mi:"MI:2287"(identification by structure determination) uniprotkb:P0ABE7 uniprotkb:P63096 intact:EBI-1120486|uniprotkb:P00192|uniprotkb:P76805|uniprotkb:Q8XCE3 intact:EBI-618639|ensembl:ENSP00000497051|ensembl:ENSP00000497179|ensembl:ENSP00000497260|ensembl:ENSP00000497315|ensembl:ENSP00000497379|ensembl:ENSP00000497717|ensembl:ENSP00000497754|ensembl:ENSP00000497760|ensembl:ENSP00000497765|ensembl:ENSP00000497773|ensembl:ENSP00000498091|ensembl:ENSP00000343027|ensembl:ENSP00000391439|ensembl:ENSP00000496800|ensembl:ENSP00000496829|uniprotkb:P04898|uniprotkb:P11015|uniprotkb:P31871|uniprotkb:Q5U074|uniprotkb:Q8TAN5|uniprotkb:Q9UGA4|uniprotkb:A8KA88|uniprotkb:B4E2V1|uniprotkb:C9J3A4 psi-mi:c562_ecolx(display_long)|uniprotkb:cybC(gene name)|psi-mi:cybC(display_short) psi-mi:gnai1_human(display_long)|uniprotkb:GNAI1(gene name)|psi-mi:GNAI1(display_short)|uniprotkb:Adenylate cyclase-inhibiting G alpha protein(gene name synonym) psi-mi:"MI:0410"(3D electron microscopy) Kang et al. (2018) pubmed:29899450|imex:IM-28379 taxid:562(ecolx)|taxid:562(Escherichia coli) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0465"(DIP) intact:EBI-25681738|wwpdb:6CMO|emdb:EMD-7517|imex:IM-28379-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) rcsb pdb:3M4C|rcsb pdb:3M79|rcsb pdb:3NMI|rcsb pdb:3NMJ|rcsb pdb:3NMK|rcsb pdb:3TOL|rcsb pdb:3TOM|rcsb pdb:4IAQ|rcsb pdb:3U8P|rcsb pdb:4PXZ|rcsb pdb:4PY0|rcsb pdb:5DHG|rcsb pdb:4RWA|rcsb pdb:4RWD|rcsb pdb:4U9D|rcsb pdb:4L6R|rcsb pdb:4N6H|rcsb pdb:4NC3|rcsb pdb:5YO4|rcsb pdb:5YO5|rcsb pdb:5YO6|rcsb pdb:4QIM|rcsb pdb:4QIN|interpro:IPR009155(Cytochrome b562)|interpro:IPR010980(Cytochrome c and b562)|rcsb pdb:1APC|rcsb pdb:1LM3|rcsb pdb:1M6T|rcsb pdb:1QPU|rcsb pdb:1QQ3|rcsb pdb:256B|rcsb pdb:2BC5|rcsb pdb:2QLA|rcsb pdb:3C62|rcsb pdb:3C63|rcsb pdb:3DE8|rcsb pdb:3DE9|rcsb pdb:3FOO|rcsb pdb:3FOP|rcsb pdb:3HNI|rcsb pdb:3HNJ|rcsb pdb:4Z34|rcsb pdb:4Z35|rcsb pdb:4Z36|rcsb pdb:3HNK|rcsb pdb:3HNL|rcsb pdb:3IQ5|rcsb pdb:3IQ6|rcsb pdb:3L1M|rcsb pdb:3M15|rcsb pdb:3M4B|rcsb pdb:6BQG|rcsb pdb:6BQH|rcsb pdb:6AK3|rcsb pdb:6G7O|rcsb pdb:6IIU|rcsb pdb:6IIV|go:"GO:0005506"(iron ion binding)|go:"GO:0009055"(electron transfer activity)|go:"GO:0020037"(heme binding)|go:"GO:0042597"(periplasmic space)|rcsb pdb:6LPJ|rcsb pdb:6LPK|rcsb pdb:6LPL|rcsb pdb:6WQA|rcsb pdb:7DFP|rcsb pdb:6ME6|rcsb pdb:6ME7|rcsb pdb:6ME8|rcsb pdb:6ME9|rcsb pdb:6MH8|rcsb pdb:4ZUD|rcsb pdb:5AWI|rcsb pdb:5YO3|rcsb pdb:6DY4|rcsb pdb:6DY6|rcsb pdb:6DY8|rcsb pdb:6DYB|rcsb pdb:6DYC|rcsb pdb:6DYD|rcsb pdb:6DYE|rcsb pdb:6DYF|rcsb pdb:6DYG|rcsb pdb:6DYH|rcsb pdb:6DYI|rcsb pdb:6DYJ|rcsb pdb:6DYK|rcsb pdb:6DYL|rcsb pdb:6M97|rcsb pdb:6M98|rcsb pdb:5UEN|rcsb pdb:4EIY|rcsb pdb:4IAR|rcsb pdb:4IB4|rcsb pdb:4JE9|rcsb pdb:4JEA|rcsb pdb:4JEB|rcsb pdb:4YAY|rcsb pdb:4EA3|rcsb pdb:7JVR|rcsb pdb:4JKV|rcsb pdb:6GT3|rcsb pdb:6S0Q|rcsb pdb:5WIU|rcsb pdb:5WIV|rcsb pdb:6LW5|rcsb pdb:6OS0|rcsb pdb:6OS1|rcsb pdb:6OS2|rcsb pdb:6OT4|rcsb pdb:6OT7|rcsb pdb:6OT8|rcsb pdb:6OT9|rcsb pdb:6OVH|rcsb pdb:4O9R|rcsb pdb:5IU4|rcsb pdb:5IU7|rcsb pdb:5IU8|rcsb pdb:5IUA|rcsb pdb:5IUB|rcsb pdb:5K2A|rcsb pdb:5K2B|rcsb pdb:5L7D|rcsb pdb:5L7I|rcsb pdb:7ARO|rcsb pdb:7CMU|rcsb pdb:7CMV|rcsb pdb:7E2X|rcsb pdb:7E2Y|rcsb pdb:7E2Z|rcsb pdb:7E32|rcsb pdb:7E33|rcsb pdb:7KOO|rcsb pdb:7KOQ|rcsb pdb:7KOX|rcsb pdb:4NTJ|rcsb pdb:4OR2|rcsb pdb:6DO1|rcsb pdb:6CC4|rcsb pdb:6CMO|rcsb pdb:5BU7|rcsb pdb:4U9E|refseq:WP_001232240.1|rcsb pdb:6C1Q|rcsb pdb:6C1R|rcsb pdb:6D32|rcsb pdb:6D35|rcsb pdb:6UR8|rcsb pdb:6USF|rcsb pdb:5JTB|rcsb pdb:5UVI|rcsb pdb:5K2C|rcsb pdb:5K2D|rcsb pdb:5L31|rcsb pdb:5L32|rcsb pdb:5TVN|rcsb pdb:5OLG|rcsb pdb:5OLH|rcsb pdb:5OLO|rcsb pdb:5OLV|rcsb pdb:5OLZ|rcsb pdb:5OM1|rcsb pdb:5OM4|rcsb pdb:5VRA|rcsb pdb:5XZI|rcsb pdb:5XZJ|rcsb pdb:6AQF|rcsb pdb:6B73|rcsb pdb:5UIG|rcsb pdb:5UNF|rcsb pdb:5UNG|rcsb pdb:5UNH|rcsb pdb:5NDD|rcsb pdb:5NDZ|rcsb pdb:5NJ6|rcsb pdb:5DHH|rcsb pdb:5MZJ|rcsb pdb:5MZP|rcsb pdb:5N2R|rcsb pdb:5N2S|rcsb pdb:5TUD|rcsb pdb:5NLX|rcsb pdb:5NM2|rcsb pdb:5NM4|rcsb pdb:5YM7|rcsb pdb:5XJM|rcsb pdb:6DHY|rcsb pdb:6DHZ|rcsb pdb:6DRX|rcsb pdb:6DRY|rcsb pdb:6DRZ|rcsb pdb:6DS0|rcsb pdb:6A93|rcsb pdb:6A94|rcsb pdb:6CBV|rcsb pdb:6AI5|rcsb pdb:6JZH|rcsb pdb:6PS7|rcsb pdb:6RZ4|rcsb pdb:6RZ5|rcsb pdb:6IQL|rcsb pdb:6JOD|rcsb pdb:6RZ6|rcsb pdb:6RZ7|rcsb pdb:6RZ8|rcsb pdb:6RZ9|rcsb pdb:6KO5|rcsb pdb:6WW2|rcsb pdb:6WWZ|rcsb pdb:7BW0|rcsb pdb:7C61|rcsb pdb:7C6A|rcsb pdb:6WGT|rcsb pdb:6WH4|rcsb pdb:6WHA|rcsb pdb:6WYU|rcsb pdb:6WZ0|rcsb pdb:6WZ1|rcsb pdb:6WZ2|rcsb pdb:6WZ3|rcsb pdb:6WZ7|rcsb pdb:6WZA|rcsb pdb:6WZC|rcsb pdb:6X7E|rcsb pdb:6X8X|rcsb pdb:6ZDR|rcsb pdb:6ZDV reactome:R-HSA-418597|reactome:R-HSA-422356|reactome:R-HSA-9009391|reactome:R-HSA-9660821|reactome:R-HSA-418594|ensembl:ENST00000351004(transcript)|ensembl:ENST00000442586(transcript)|ensembl:ENST00000648098(transcript)|ensembl:ENSG00000127955(gene)|ensembl:ENST00000648306(transcript)|ensembl:ENST00000648412(transcript)|ensembl:ENST00000648476(transcript)|ensembl:ENST00000648663(transcript)|ensembl:ENST00000648832(transcript)|ensembl:ENST00000648877(transcript)|ensembl:ENST00000648953(transcript)|ensembl:ENST00000649225(transcript)|ensembl:ENST00000649267(transcript)|ensembl:ENST00000649487(transcript)|ensembl:ENST00000649796(transcript)|ensembl:ENST00000649855(transcript)|go:"GO:0000287"(magnesium ion binding)|go:"GO:0001664"(G protein-coupled receptor binding)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005813"(centrosome)|go:"GO:0005834"(heterotrimeric G-protein complex)|go:"GO:0005886"(plasma membrane)|go:"GO:0007049"(cell cycle)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0007188"(adenylate cyclase-modulating G protein-coupled receptor signaling pathway)|go:"GO:0007193"(adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway)|go:"GO:0019003"(GDP binding)|go:"GO:0030496"(midbody)|go:"GO:0031683"(G-protein beta/gamma-subunit complex binding)|go:"GO:0031821"(G protein-coupled serotonin receptor binding)|go:"GO:0032794"(GTPase activating protein binding)|go:"GO:0043434"(response to peptide hormone)|go:"GO:0043949"(regulation of cAMP-mediated signaling)|go:"GO:0045121"(membrane raft)|go:"GO:0050805"(negative regulation of synaptic transmission)|go:"GO:0051301"(cell division)|go:"GO:0060236"(regulation of mitotic spindle organization)|go:"GO:0070062"(extracellular exosome)|go:"GO:0099738"(cell cortex region)|go:"GO:1904322"(cellular response to forskolin)|go:"GO:1904778"(positive regulation of protein localization to cell cortex)|interpro:IPR001019("Guanine nucleotide binding protein (G-protein), alpha subunit")|interpro:IPR001408(G-protein alpha subunit, group I)|interpro:IPR011025(G protein alpha subunit, helical insertion)|interpro:IPR027417|mint:P63096|rcsb pdb:1KJY|rcsb pdb:1Y3A|rcsb pdb:2G83|rcsb pdb:2GTP|rcsb pdb:2IK8|rcsb pdb:2OM2|rcsb pdb:2XNS|rcsb pdb:3ONW|rcsb pdb:3QE0|rcsb pdb:3QI2|rcsb pdb:3UMR|rcsb pdb:3UMS|rcsb pdb:4G5Q|rcsb pdb:5JS7|rcsb pdb:5JS8|rcsb pdb:5TDH|rcsb pdb:6CMO|rcsb pdb:6CRK|rcsb pdb:6DDE|rcsb pdb:6DDF|rcsb pdb:6KPF|rcsb pdb:6KPG|rcsb pdb:6LFM|rcsb pdb:6LFO|rcsb pdb:6LML|rcsb pdb:6N4B|rcsb pdb:6OMM|rcsb pdb:6OS9|rcsb pdb:6OSA|rcsb pdb:6OT0|rcsb pdb:6PB0|rcsb pdb:6PB1|rcsb pdb:6PT0|rcsb pdb:6QNO|rcsb pdb:6VU8|rcsb pdb:6XBJ|rcsb pdb:6XBK|rcsb pdb:6XBL|rcsb pdb:6XBM|rcsb pdb:7CMU|rcsb pdb:7CMV|rcsb pdb:7E2X|rcsb pdb:7E2Y|rcsb pdb:7E2Z|rcsb pdb:7E32|rcsb pdb:7E33|rcsb pdb:7E9G|rcsb pdb:7EB2|rcsb pdb:7JVR|rcsb pdb:7L0P|rcsb pdb:7L0Q|rcsb pdb:7L0R|rcsb pdb:7L0S|rcsb pdb:7O7F|reactome:R-HSA-170670|reactome:R-HSA-392170|reactome:R-HSA-400042|reactome:R-HSA-418555|refseq:NP_002060.4|refseq:NP_001243343.1 - - - figure legend:Fig 2, Extended Data Fig 2, Extended Data Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2020/06/17 2021/04/19 rogid:O9HPXjm/UQpqt+WPfwjDOEx8+m4562 rogid:3yQOCXJb8Undp/Xw42xrBiG5ePE9606 rigid:byUWCYFrBR1Dh68SItQ8WMUKU8E false - his tag:n-n|maltose binding protein tag:n-n 1 1 psi-mi:"MI:0396"(predetermined participant)|psi-mi:"MI:2287"(identification by structure determination) psi-mi:"MI:0396"(predetermined participant)|psi-mi:"MI:2287"(identification by structure determination) uniprotkb:P0ABE7 intact:EBI-26956493 intact:EBI-1120486|uniprotkb:P00192|uniprotkb:P76805|uniprotkb:Q8XCE3 - psi-mi:c562_ecolx(display_long)|uniprotkb:cybC(gene name)|psi-mi:cybC(display_short) psi-mi:fab_hc_synthetic(display_short)|psi-mi:EBI-26956493(display_long) psi-mi:"MI:0071"(molecular sieving) Kang et al. (2018) pubmed:29899450|imex:IM-28379 taxid:562(ecolx)|taxid:562(Escherichia coli) taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0465"(DIP) intact:EBI-25681765|imex:IM-28379-3 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) rcsb pdb:3M4C|rcsb pdb:3M79|rcsb pdb:3NMI|rcsb pdb:3NMJ|rcsb pdb:3NMK|rcsb pdb:3TOL|rcsb pdb:3TOM|rcsb pdb:4IAQ|rcsb pdb:3U8P|rcsb pdb:4PXZ|rcsb pdb:4PY0|rcsb pdb:5DHG|rcsb pdb:4RWA|rcsb pdb:4RWD|rcsb pdb:4U9D|rcsb pdb:4L6R|rcsb pdb:4N6H|rcsb pdb:4NC3|rcsb pdb:5YO4|rcsb pdb:5YO5|rcsb pdb:5YO6|rcsb pdb:4QIM|rcsb pdb:4QIN|interpro:IPR009155(Cytochrome b562)|interpro:IPR010980(Cytochrome c and b562)|rcsb pdb:1APC|rcsb pdb:1LM3|rcsb pdb:1M6T|rcsb pdb:1QPU|rcsb pdb:1QQ3|rcsb pdb:256B|rcsb pdb:2BC5|rcsb pdb:2QLA|rcsb pdb:3C62|rcsb pdb:3C63|rcsb pdb:3DE8|rcsb pdb:3DE9|rcsb pdb:3FOO|rcsb pdb:3FOP|rcsb pdb:3HNI|rcsb pdb:3HNJ|rcsb pdb:4Z34|rcsb pdb:4Z35|rcsb pdb:4Z36|rcsb pdb:3HNK|rcsb pdb:3HNL|rcsb pdb:3IQ5|rcsb pdb:3IQ6|rcsb pdb:3L1M|rcsb pdb:3M15|rcsb pdb:3M4B|rcsb pdb:6BQG|rcsb pdb:6BQH|rcsb pdb:6AK3|rcsb pdb:6G7O|rcsb pdb:6IIU|rcsb pdb:6IIV|go:"GO:0005506"(iron ion binding)|go:"GO:0009055"(electron transfer activity)|go:"GO:0020037"(heme binding)|go:"GO:0042597"(periplasmic space)|rcsb pdb:6LPJ|rcsb pdb:6LPK|rcsb pdb:6LPL|rcsb pdb:6WQA|rcsb pdb:7DFP|rcsb pdb:6ME6|rcsb pdb:6ME7|rcsb pdb:6ME8|rcsb pdb:6ME9|rcsb pdb:6MH8|rcsb pdb:4ZUD|rcsb pdb:5AWI|rcsb pdb:5YO3|rcsb pdb:6DY4|rcsb pdb:6DY6|rcsb pdb:6DY8|rcsb pdb:6DYB|rcsb pdb:6DYC|rcsb pdb:6DYD|rcsb pdb:6DYE|rcsb pdb:6DYF|rcsb pdb:6DYG|rcsb pdb:6DYH|rcsb pdb:6DYI|rcsb pdb:6DYJ|rcsb pdb:6DYK|rcsb pdb:6DYL|rcsb pdb:6M97|rcsb pdb:6M98|rcsb pdb:5UEN|rcsb pdb:4EIY|rcsb pdb:4IAR|rcsb pdb:4IB4|rcsb pdb:4JE9|rcsb pdb:4JEA|rcsb pdb:4JEB|rcsb pdb:4YAY|rcsb pdb:4EA3|rcsb pdb:7JVR|rcsb pdb:4JKV|rcsb pdb:6GT3|rcsb pdb:6S0Q|rcsb pdb:5WIU|rcsb pdb:5WIV|rcsb pdb:6LW5|rcsb pdb:6OS0|rcsb pdb:6OS1|rcsb pdb:6OS2|rcsb pdb:6OT4|rcsb pdb:6OT7|rcsb pdb:6OT8|rcsb pdb:6OT9|rcsb pdb:6OVH|rcsb pdb:4O9R|rcsb pdb:5IU4|rcsb pdb:5IU7|rcsb pdb:5IU8|rcsb pdb:5IUA|rcsb pdb:5IUB|rcsb pdb:5K2A|rcsb pdb:5K2B|rcsb pdb:5L7D|rcsb pdb:5L7I|rcsb pdb:7ARO|rcsb pdb:7CMU|rcsb pdb:7CMV|rcsb pdb:7E2X|rcsb pdb:7E2Y|rcsb pdb:7E2Z|rcsb pdb:7E32|rcsb pdb:7E33|rcsb pdb:7KOO|rcsb pdb:7KOQ|rcsb pdb:7KOX|rcsb pdb:4NTJ|rcsb pdb:4OR2|rcsb pdb:6DO1|rcsb pdb:6CC4|rcsb pdb:6CMO|rcsb pdb:5BU7|rcsb pdb:4U9E|refseq:WP_001232240.1|rcsb pdb:6C1Q|rcsb pdb:6C1R|rcsb pdb:6D32|rcsb pdb:6D35|rcsb pdb:6UR8|rcsb pdb:6USF|rcsb pdb:5JTB|rcsb pdb:5UVI|rcsb pdb:5K2C|rcsb pdb:5K2D|rcsb pdb:5L31|rcsb pdb:5L32|rcsb pdb:5TVN|rcsb pdb:5OLG|rcsb pdb:5OLH|rcsb pdb:5OLO|rcsb pdb:5OLV|rcsb pdb:5OLZ|rcsb pdb:5OM1|rcsb pdb:5OM4|rcsb pdb:5VRA|rcsb pdb:5XZI|rcsb pdb:5XZJ|rcsb pdb:6AQF|rcsb pdb:6B73|rcsb pdb:5UIG|rcsb pdb:5UNF|rcsb pdb:5UNG|rcsb pdb:5UNH|rcsb pdb:5NDD|rcsb pdb:5NDZ|rcsb pdb:5NJ6|rcsb pdb:5DHH|rcsb pdb:5MZJ|rcsb pdb:5MZP|rcsb pdb:5N2R|rcsb pdb:5N2S|rcsb pdb:5TUD|rcsb pdb:5NLX|rcsb pdb:5NM2|rcsb pdb:5NM4|rcsb pdb:5YM7|rcsb pdb:5XJM|rcsb pdb:6DHY|rcsb pdb:6DHZ|rcsb pdb:6DRX|rcsb pdb:6DRY|rcsb pdb:6DRZ|rcsb pdb:6DS0|rcsb pdb:6A93|rcsb pdb:6A94|rcsb pdb:6CBV|rcsb pdb:6AI5|rcsb pdb:6JZH|rcsb pdb:6PS7|rcsb pdb:6RZ4|rcsb pdb:6RZ5|rcsb pdb:6IQL|rcsb pdb:6JOD|rcsb pdb:6RZ6|rcsb pdb:6RZ7|rcsb pdb:6RZ8|rcsb pdb:6RZ9|rcsb pdb:6KO5|rcsb pdb:6WW2|rcsb pdb:6WWZ|rcsb pdb:7BW0|rcsb pdb:7C61|rcsb pdb:7C6A|rcsb pdb:6WGT|rcsb pdb:6WH4|rcsb pdb:6WHA|rcsb pdb:6WYU|rcsb pdb:6WZ0|rcsb pdb:6WZ1|rcsb pdb:6WZ2|rcsb pdb:6WZ3|rcsb pdb:6WZ7|rcsb pdb:6WZA|rcsb pdb:6WZC|rcsb pdb:6X7E|rcsb pdb:6X8X|rcsb pdb:6ZDR|rcsb pdb:6ZDV pdbe:6cmo(see-also) - - - figure legend:Extended Data Fig 1a, b|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2020/06/17 2021/04/19 rogid:O9HPXjm/UQpqt+WPfwjDOEx8+m4562 rogid:kHdKFIFlPHbrvQ6sMkg60vnYRcM-2 rigid:byUWCYFrBR1Dh68SItQ8WMUKU8E false - - 1 - psi-mi:"MI:0396"(predetermined participant)|psi-mi:"MI:2287"(identification by structure determination) psi-mi:"MI:0816"(molecular weight estimation by staining) uniprotkb:P0ABE7 intact:EBI-26956490 intact:EBI-1120486|uniprotkb:P00192|uniprotkb:P76805|uniprotkb:Q8XCE3 - psi-mi:c562_ecolx(display_long)|uniprotkb:cybC(gene name)|psi-mi:cybC(display_short) psi-mi:fab_lc_synthetic(display_short)|psi-mi:EBI-26956490(display_long) psi-mi:"MI:0071"(molecular sieving) Kang et al. (2018) pubmed:29899450|imex:IM-28379 taxid:562(ecolx)|taxid:562(Escherichia coli) taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0465"(DIP) intact:EBI-25681765|imex:IM-28379-3 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) rcsb pdb:3M4C|rcsb pdb:3M79|rcsb pdb:3NMI|rcsb pdb:3NMJ|rcsb pdb:3NMK|rcsb pdb:3TOL|rcsb pdb:3TOM|rcsb pdb:4IAQ|rcsb pdb:3U8P|rcsb pdb:4PXZ|rcsb pdb:4PY0|rcsb pdb:5DHG|rcsb pdb:4RWA|rcsb pdb:4RWD|rcsb pdb:4U9D|rcsb pdb:4L6R|rcsb pdb:4N6H|rcsb pdb:4NC3|rcsb pdb:5YO4|rcsb pdb:5YO5|rcsb pdb:5YO6|rcsb pdb:4QIM|rcsb pdb:4QIN|interpro:IPR009155(Cytochrome b562)|interpro:IPR010980(Cytochrome c and b562)|rcsb pdb:1APC|rcsb pdb:1LM3|rcsb pdb:1M6T|rcsb pdb:1QPU|rcsb pdb:1QQ3|rcsb pdb:256B|rcsb pdb:2BC5|rcsb pdb:2QLA|rcsb pdb:3C62|rcsb pdb:3C63|rcsb pdb:3DE8|rcsb pdb:3DE9|rcsb pdb:3FOO|rcsb pdb:3FOP|rcsb pdb:3HNI|rcsb pdb:3HNJ|rcsb pdb:4Z34|rcsb pdb:4Z35|rcsb pdb:4Z36|rcsb pdb:3HNK|rcsb pdb:3HNL|rcsb pdb:3IQ5|rcsb pdb:3IQ6|rcsb pdb:3L1M|rcsb pdb:3M15|rcsb pdb:3M4B|rcsb pdb:6BQG|rcsb pdb:6BQH|rcsb pdb:6AK3|rcsb pdb:6G7O|rcsb pdb:6IIU|rcsb pdb:6IIV|go:"GO:0005506"(iron ion binding)|go:"GO:0009055"(electron transfer activity)|go:"GO:0020037"(heme binding)|go:"GO:0042597"(periplasmic space)|rcsb pdb:6LPJ|rcsb pdb:6LPK|rcsb pdb:6LPL|rcsb pdb:6WQA|rcsb pdb:7DFP|rcsb pdb:6ME6|rcsb pdb:6ME7|rcsb pdb:6ME8|rcsb pdb:6ME9|rcsb pdb:6MH8|rcsb pdb:4ZUD|rcsb pdb:5AWI|rcsb pdb:5YO3|rcsb pdb:6DY4|rcsb pdb:6DY6|rcsb pdb:6DY8|rcsb pdb:6DYB|rcsb pdb:6DYC|rcsb pdb:6DYD|rcsb pdb:6DYE|rcsb pdb:6DYF|rcsb pdb:6DYG|rcsb pdb:6DYH|rcsb pdb:6DYI|rcsb pdb:6DYJ|rcsb pdb:6DYK|rcsb pdb:6DYL|rcsb pdb:6M97|rcsb pdb:6M98|rcsb pdb:5UEN|rcsb pdb:4EIY|rcsb pdb:4IAR|rcsb pdb:4IB4|rcsb pdb:4JE9|rcsb pdb:4JEA|rcsb pdb:4JEB|rcsb pdb:4YAY|rcsb pdb:4EA3|rcsb pdb:7JVR|rcsb pdb:4JKV|rcsb pdb:6GT3|rcsb pdb:6S0Q|rcsb pdb:5WIU|rcsb pdb:5WIV|rcsb pdb:6LW5|rcsb pdb:6OS0|rcsb pdb:6OS1|rcsb pdb:6OS2|rcsb pdb:6OT4|rcsb pdb:6OT7|rcsb pdb:6OT8|rcsb pdb:6OT9|rcsb pdb:6OVH|rcsb pdb:4O9R|rcsb pdb:5IU4|rcsb pdb:5IU7|rcsb pdb:5IU8|rcsb pdb:5IUA|rcsb pdb:5IUB|rcsb pdb:5K2A|rcsb pdb:5K2B|rcsb pdb:5L7D|rcsb pdb:5L7I|rcsb pdb:7ARO|rcsb pdb:7CMU|rcsb pdb:7CMV|rcsb pdb:7E2X|rcsb pdb:7E2Y|rcsb pdb:7E2Z|rcsb pdb:7E32|rcsb pdb:7E33|rcsb pdb:7KOO|rcsb pdb:7KOQ|rcsb pdb:7KOX|rcsb pdb:4NTJ|rcsb pdb:4OR2|rcsb pdb:6DO1|rcsb pdb:6CC4|rcsb pdb:6CMO|rcsb pdb:5BU7|rcsb pdb:4U9E|refseq:WP_001232240.1|rcsb pdb:6C1Q|rcsb pdb:6C1R|rcsb pdb:6D32|rcsb pdb:6D35|rcsb pdb:6UR8|rcsb pdb:6USF|rcsb pdb:5JTB|rcsb pdb:5UVI|rcsb pdb:5K2C|rcsb pdb:5K2D|rcsb pdb:5L31|rcsb pdb:5L32|rcsb pdb:5TVN|rcsb pdb:5OLG|rcsb pdb:5OLH|rcsb pdb:5OLO|rcsb pdb:5OLV|rcsb pdb:5OLZ|rcsb pdb:5OM1|rcsb pdb:5OM4|rcsb pdb:5VRA|rcsb pdb:5XZI|rcsb pdb:5XZJ|rcsb pdb:6AQF|rcsb pdb:6B73|rcsb pdb:5UIG|rcsb pdb:5UNF|rcsb pdb:5UNG|rcsb pdb:5UNH|rcsb pdb:5NDD|rcsb pdb:5NDZ|rcsb pdb:5NJ6|rcsb pdb:5DHH|rcsb pdb:5MZJ|rcsb pdb:5MZP|rcsb pdb:5N2R|rcsb pdb:5N2S|rcsb pdb:5TUD|rcsb pdb:5NLX|rcsb pdb:5NM2|rcsb pdb:5NM4|rcsb pdb:5YM7|rcsb pdb:5XJM|rcsb pdb:6DHY|rcsb pdb:6DHZ|rcsb pdb:6DRX|rcsb pdb:6DRY|rcsb pdb:6DRZ|rcsb pdb:6DS0|rcsb pdb:6A93|rcsb pdb:6A94|rcsb pdb:6CBV|rcsb pdb:6AI5|rcsb pdb:6JZH|rcsb pdb:6PS7|rcsb pdb:6RZ4|rcsb pdb:6RZ5|rcsb pdb:6IQL|rcsb pdb:6JOD|rcsb pdb:6RZ6|rcsb pdb:6RZ7|rcsb pdb:6RZ8|rcsb pdb:6RZ9|rcsb pdb:6KO5|rcsb pdb:6WW2|rcsb pdb:6WWZ|rcsb pdb:7BW0|rcsb pdb:7C61|rcsb pdb:7C6A|rcsb pdb:6WGT|rcsb pdb:6WH4|rcsb pdb:6WHA|rcsb pdb:6WYU|rcsb pdb:6WZ0|rcsb pdb:6WZ1|rcsb pdb:6WZ2|rcsb pdb:6WZ3|rcsb pdb:6WZ7|rcsb pdb:6WZA|rcsb pdb:6WZC|rcsb pdb:6X7E|rcsb pdb:6X8X|rcsb pdb:6ZDR|rcsb pdb:6ZDV pdbe:6cmo(see-also) - - - figure legend:Extended Data Fig 1a, b|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2020/06/17 2021/04/19 rogid:O9HPXjm/UQpqt+WPfwjDOEx8+m4562 rogid:FFTkG2YdM9f48AtYDB+EHMKETWQ-2 rigid:byUWCYFrBR1Dh68SItQ8WMUKU8E false - - 1 - psi-mi:"MI:0396"(predetermined participant)|psi-mi:"MI:2287"(identification by structure determination) psi-mi:"MI:0816"(molecular weight estimation by staining) uniprotkb:P0ABE7 uniprotkb:P54311 intact:EBI-1120486|uniprotkb:P00192|uniprotkb:P76805|uniprotkb:Q8XCE3 intact:EBI-917779|uniprotkb:Q6Q8B1|uniprotkb:Q9QWG8|ensembl:ENSRNOP00000044340 psi-mi:c562_ecolx(display_long)|uniprotkb:cybC(gene name)|psi-mi:cybC(display_short) psi-mi:gbb1_rat(display_long)|uniprotkb:Transducin beta chain 1(gene name synonym)|uniprotkb:Gnb1(gene name)|psi-mi:Gnb1(display_short) psi-mi:"MI:0071"(molecular sieving) Kang et al. (2018) pubmed:29899450|imex:IM-28379 taxid:562(ecolx)|taxid:562(Escherichia coli) taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0465"(DIP) intact:EBI-25681765|imex:IM-28379-3 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) rcsb pdb:3M4C|rcsb pdb:3M79|rcsb pdb:3NMI|rcsb pdb:3NMJ|rcsb pdb:3NMK|rcsb pdb:3TOL|rcsb pdb:3TOM|rcsb pdb:4IAQ|rcsb pdb:3U8P|rcsb pdb:4PXZ|rcsb pdb:4PY0|rcsb pdb:5DHG|rcsb pdb:4RWA|rcsb pdb:4RWD|rcsb pdb:4U9D|rcsb pdb:4L6R|rcsb pdb:4N6H|rcsb pdb:4NC3|rcsb pdb:5YO4|rcsb pdb:5YO5|rcsb pdb:5YO6|rcsb pdb:4QIM|rcsb pdb:4QIN|interpro:IPR009155(Cytochrome b562)|interpro:IPR010980(Cytochrome c and b562)|rcsb pdb:1APC|rcsb pdb:1LM3|rcsb pdb:1M6T|rcsb pdb:1QPU|rcsb pdb:1QQ3|rcsb pdb:256B|rcsb pdb:2BC5|rcsb pdb:2QLA|rcsb pdb:3C62|rcsb pdb:3C63|rcsb pdb:3DE8|rcsb pdb:3DE9|rcsb pdb:3FOO|rcsb pdb:3FOP|rcsb pdb:3HNI|rcsb pdb:3HNJ|rcsb pdb:4Z34|rcsb pdb:4Z35|rcsb pdb:4Z36|rcsb pdb:3HNK|rcsb pdb:3HNL|rcsb pdb:3IQ5|rcsb pdb:3IQ6|rcsb pdb:3L1M|rcsb pdb:3M15|rcsb pdb:3M4B|rcsb pdb:6BQG|rcsb pdb:6BQH|rcsb pdb:6AK3|rcsb pdb:6G7O|rcsb pdb:6IIU|rcsb pdb:6IIV|go:"GO:0005506"(iron ion binding)|go:"GO:0009055"(electron transfer activity)|go:"GO:0020037"(heme binding)|go:"GO:0042597"(periplasmic space)|rcsb pdb:6LPJ|rcsb pdb:6LPK|rcsb pdb:6LPL|rcsb pdb:6WQA|rcsb pdb:7DFP|rcsb pdb:6ME6|rcsb pdb:6ME7|rcsb pdb:6ME8|rcsb pdb:6ME9|rcsb pdb:6MH8|rcsb pdb:4ZUD|rcsb pdb:5AWI|rcsb pdb:5YO3|rcsb pdb:6DY4|rcsb pdb:6DY6|rcsb pdb:6DY8|rcsb pdb:6DYB|rcsb pdb:6DYC|rcsb pdb:6DYD|rcsb pdb:6DYE|rcsb pdb:6DYF|rcsb pdb:6DYG|rcsb pdb:6DYH|rcsb pdb:6DYI|rcsb pdb:6DYJ|rcsb pdb:6DYK|rcsb pdb:6DYL|rcsb pdb:6M97|rcsb pdb:6M98|rcsb pdb:5UEN|rcsb pdb:4EIY|rcsb pdb:4IAR|rcsb pdb:4IB4|rcsb pdb:4JE9|rcsb pdb:4JEA|rcsb pdb:4JEB|rcsb pdb:4YAY|rcsb pdb:4EA3|rcsb pdb:7JVR|rcsb pdb:4JKV|rcsb pdb:6GT3|rcsb pdb:6S0Q|rcsb pdb:5WIU|rcsb pdb:5WIV|rcsb pdb:6LW5|rcsb pdb:6OS0|rcsb pdb:6OS1|rcsb pdb:6OS2|rcsb pdb:6OT4|rcsb pdb:6OT7|rcsb pdb:6OT8|rcsb pdb:6OT9|rcsb pdb:6OVH|rcsb pdb:4O9R|rcsb pdb:5IU4|rcsb pdb:5IU7|rcsb pdb:5IU8|rcsb pdb:5IUA|rcsb pdb:5IUB|rcsb pdb:5K2A|rcsb pdb:5K2B|rcsb pdb:5L7D|rcsb pdb:5L7I|rcsb pdb:7ARO|rcsb pdb:7CMU|rcsb pdb:7CMV|rcsb pdb:7E2X|rcsb pdb:7E2Y|rcsb pdb:7E2Z|rcsb pdb:7E32|rcsb pdb:7E33|rcsb pdb:7KOO|rcsb pdb:7KOQ|rcsb pdb:7KOX|rcsb pdb:4NTJ|rcsb pdb:4OR2|rcsb pdb:6DO1|rcsb pdb:6CC4|rcsb pdb:6CMO|rcsb pdb:5BU7|rcsb pdb:4U9E|refseq:WP_001232240.1|rcsb pdb:6C1Q|rcsb pdb:6C1R|rcsb pdb:6D32|rcsb pdb:6D35|rcsb pdb:6UR8|rcsb pdb:6USF|rcsb pdb:5JTB|rcsb pdb:5UVI|rcsb pdb:5K2C|rcsb pdb:5K2D|rcsb pdb:5L31|rcsb pdb:5L32|rcsb pdb:5TVN|rcsb pdb:5OLG|rcsb pdb:5OLH|rcsb pdb:5OLO|rcsb pdb:5OLV|rcsb pdb:5OLZ|rcsb pdb:5OM1|rcsb pdb:5OM4|rcsb pdb:5VRA|rcsb pdb:5XZI|rcsb pdb:5XZJ|rcsb pdb:6AQF|rcsb pdb:6B73|rcsb pdb:5UIG|rcsb pdb:5UNF|rcsb pdb:5UNG|rcsb pdb:5UNH|rcsb pdb:5NDD|rcsb pdb:5NDZ|rcsb pdb:5NJ6|rcsb pdb:5DHH|rcsb pdb:5MZJ|rcsb pdb:5MZP|rcsb pdb:5N2R|rcsb pdb:5N2S|rcsb pdb:5TUD|rcsb pdb:5NLX|rcsb pdb:5NM2|rcsb pdb:5NM4|rcsb pdb:5YM7|rcsb pdb:5XJM|rcsb pdb:6DHY|rcsb pdb:6DHZ|rcsb pdb:6DRX|rcsb pdb:6DRY|rcsb pdb:6DRZ|rcsb pdb:6DS0|rcsb pdb:6A93|rcsb pdb:6A94|rcsb pdb:6CBV|rcsb pdb:6AI5|rcsb pdb:6JZH|rcsb pdb:6PS7|rcsb pdb:6RZ4|rcsb pdb:6RZ5|rcsb pdb:6IQL|rcsb pdb:6JOD|rcsb pdb:6RZ6|rcsb pdb:6RZ7|rcsb pdb:6RZ8|rcsb pdb:6RZ9|rcsb pdb:6KO5|rcsb pdb:6WW2|rcsb pdb:6WWZ|rcsb pdb:7BW0|rcsb pdb:7C61|rcsb pdb:7C6A|rcsb pdb:6WGT|rcsb pdb:6WH4|rcsb pdb:6WHA|rcsb pdb:6WYU|rcsb pdb:6WZ0|rcsb pdb:6WZ1|rcsb pdb:6WZ2|rcsb pdb:6WZ3|rcsb pdb:6WZ7|rcsb pdb:6WZA|rcsb pdb:6WZC|rcsb pdb:6X7E|rcsb pdb:6X8X|rcsb pdb:6ZDR|rcsb pdb:6ZDV rgd:2718|refseq:NP_112249.2|go:"GO:0001750"(photoreceptor outer segment)|go:"GO:0001917"(photoreceptor inner segment)|go:"GO:0003924"(GTPase activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005834"(heterotrimeric G-protein complex)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0007200"(phospholipase C-activating G protein-coupled receptor signaling pathway)|go:"GO:0007204"(positive regulation of cytosolic calcium ion concentration)|go:"GO:0008283"(cell population proliferation)|go:"GO:0010659"(cardiac muscle cell apoptotic process)|go:"GO:0030425"(dendrite)|go:"GO:0030507"(spectrin binding)|go:"GO:0031682"(G-protein gamma-subunit binding)|go:"GO:0042622"(photoreceptor outer segment membrane)|go:"GO:0044297"(cell body)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0047391"(alkylglycerophosphoethanolamine phosphodiesterase activity)|go:"GO:0050909"(sensory perception of taste)|ensembl:ENSRNOT00000041789(transcript)|ensembl:ENSRNOG00000016638(gene)|refseq:XP_008762557.1|refseq:XP_006239579.1|refseq:XP_017448634.1|refseq:XP_017448635.1|refseq:XP_017448636.1|refseq:XP_017448637.1|refseq:XP_017448638.1|dip:DIP-37029N|go:"GO:0051020"(GTPase binding)|go:"GO:0060041"(retina development in camera-type eye)|go:"GO:0071456"(cellular response to hypoxia)|interpro:IPR001632(G-protein, beta subunit)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR016346(Guanine nucleotide-binding protein, beta subunit)|interpro:IPR019775|interpro:IPR020472|interpro:IPR036322|mint:P54311|rcsb pdb:3SN6|rcsb pdb:5TDH|rcsb pdb:5VAI|rcsb pdb:6CMO|rcsb pdb:6LPB|rcsb pdb:6NBF|rcsb pdb:6NBH|rcsb pdb:6NBI|rcsb pdb:6WWZ|rcsb pdb:7BW0|rcsb pdb:7CZ5|rcsb pdb:7D3S|rcsb pdb:7LJC|rcsb pdb:7LJD|rcsb pdb:7MBX|rcsb pdb:7MBY|reactome:R-RNO-1296041|reactome:R-RNO-202040|reactome:R-RNO-2485179|reactome:R-RNO-381676|reactome:R-RNO-381753|reactome:R-RNO-392170|reactome:R-RNO-392451|reactome:R-RNO-400042|reactome:R-RNO-4086398|reactome:R-RNO-416476|reactome:R-RNO-418594|reactome:R-RNO-418597|reactome:R-RNO-420092|reactome:R-RNO-428930|reactome:R-RNO-432040|reactome:R-RNO-456926|reactome:R-RNO-6814122|reactome:R-RNO-8964616|reactome:R-RNO-997272 - - - figure legend:Extended Data Fig 1a, b|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2020/06/17 2021/04/19 rogid:O9HPXjm/UQpqt+WPfwjDOEx8+m4562 rogid:zP/G70MXiSQpzbyyWFTWrJFQENk10116 rigid:byUWCYFrBR1Dh68SItQ8WMUKU8E false - - 1 1 psi-mi:"MI:0396"(predetermined participant)|psi-mi:"MI:2287"(identification by structure determination) psi-mi:"MI:0396"(predetermined participant)|psi-mi:"MI:2287"(identification by structure determination) uniprotkb:P0ABE7 uniprotkb:P63212 intact:EBI-1120486|uniprotkb:P00192|uniprotkb:P76805|uniprotkb:Q8XCE3 intact:EBI-1036424|uniprotkb:P16874|uniprotkb:Q2KI31|uniprotkb:Q61013|uniprotkb:Q9TS47|ensembl:ENSBTAP00000003959 psi-mi:c562_ecolx(display_long)|uniprotkb:cybC(gene name)|psi-mi:cybC(display_short) psi-mi:gbg2_bovin(display_long)|uniprotkb:GNG2(gene name)|psi-mi:GNG2(display_short)|uniprotkb:G gamma-I(gene name synonym) psi-mi:"MI:0071"(molecular sieving) Kang et al. (2018) pubmed:29899450|imex:IM-28379 taxid:562(ecolx)|taxid:562(Escherichia coli) taxid:9913(bovin)|taxid:9913("Bos taurus (Bovine)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0465"(DIP) intact:EBI-25681765|imex:IM-28379-3 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) rcsb pdb:3M4C|rcsb pdb:3M79|rcsb pdb:3NMI|rcsb pdb:3NMJ|rcsb pdb:3NMK|rcsb pdb:3TOL|rcsb pdb:3TOM|rcsb pdb:4IAQ|rcsb pdb:3U8P|rcsb pdb:4PXZ|rcsb pdb:4PY0|rcsb pdb:5DHG|rcsb pdb:4RWA|rcsb pdb:4RWD|rcsb pdb:4U9D|rcsb pdb:4L6R|rcsb pdb:4N6H|rcsb pdb:4NC3|rcsb pdb:5YO4|rcsb pdb:5YO5|rcsb pdb:5YO6|rcsb pdb:4QIM|rcsb pdb:4QIN|interpro:IPR009155(Cytochrome b562)|interpro:IPR010980(Cytochrome c and b562)|rcsb pdb:1APC|rcsb pdb:1LM3|rcsb pdb:1M6T|rcsb pdb:1QPU|rcsb pdb:1QQ3|rcsb pdb:256B|rcsb pdb:2BC5|rcsb pdb:2QLA|rcsb pdb:3C62|rcsb pdb:3C63|rcsb pdb:3DE8|rcsb pdb:3DE9|rcsb pdb:3FOO|rcsb pdb:3FOP|rcsb pdb:3HNI|rcsb pdb:3HNJ|rcsb pdb:4Z34|rcsb pdb:4Z35|rcsb pdb:4Z36|rcsb pdb:3HNK|rcsb pdb:3HNL|rcsb pdb:3IQ5|rcsb pdb:3IQ6|rcsb pdb:3L1M|rcsb pdb:3M15|rcsb pdb:3M4B|rcsb pdb:6BQG|rcsb pdb:6BQH|rcsb pdb:6AK3|rcsb pdb:6G7O|rcsb pdb:6IIU|rcsb pdb:6IIV|go:"GO:0005506"(iron ion binding)|go:"GO:0009055"(electron transfer activity)|go:"GO:0020037"(heme binding)|go:"GO:0042597"(periplasmic space)|rcsb pdb:6LPJ|rcsb pdb:6LPK|rcsb pdb:6LPL|rcsb pdb:6WQA|rcsb pdb:7DFP|rcsb pdb:6ME6|rcsb pdb:6ME7|rcsb pdb:6ME8|rcsb pdb:6ME9|rcsb pdb:6MH8|rcsb pdb:4ZUD|rcsb pdb:5AWI|rcsb pdb:5YO3|rcsb pdb:6DY4|rcsb pdb:6DY6|rcsb pdb:6DY8|rcsb pdb:6DYB|rcsb pdb:6DYC|rcsb pdb:6DYD|rcsb pdb:6DYE|rcsb pdb:6DYF|rcsb pdb:6DYG|rcsb pdb:6DYH|rcsb pdb:6DYI|rcsb pdb:6DYJ|rcsb pdb:6DYK|rcsb pdb:6DYL|rcsb pdb:6M97|rcsb pdb:6M98|rcsb pdb:5UEN|rcsb pdb:4EIY|rcsb pdb:4IAR|rcsb pdb:4IB4|rcsb pdb:4JE9|rcsb pdb:4JEA|rcsb pdb:4JEB|rcsb pdb:4YAY|rcsb pdb:4EA3|rcsb pdb:7JVR|rcsb pdb:4JKV|rcsb pdb:6GT3|rcsb pdb:6S0Q|rcsb pdb:5WIU|rcsb pdb:5WIV|rcsb pdb:6LW5|rcsb pdb:6OS0|rcsb pdb:6OS1|rcsb pdb:6OS2|rcsb pdb:6OT4|rcsb pdb:6OT7|rcsb pdb:6OT8|rcsb pdb:6OT9|rcsb pdb:6OVH|rcsb pdb:4O9R|rcsb pdb:5IU4|rcsb pdb:5IU7|rcsb pdb:5IU8|rcsb pdb:5IUA|rcsb pdb:5IUB|rcsb pdb:5K2A|rcsb pdb:5K2B|rcsb pdb:5L7D|rcsb pdb:5L7I|rcsb pdb:7ARO|rcsb pdb:7CMU|rcsb pdb:7CMV|rcsb pdb:7E2X|rcsb pdb:7E2Y|rcsb pdb:7E2Z|rcsb pdb:7E32|rcsb pdb:7E33|rcsb pdb:7KOO|rcsb pdb:7KOQ|rcsb pdb:7KOX|rcsb pdb:4NTJ|rcsb pdb:4OR2|rcsb pdb:6DO1|rcsb pdb:6CC4|rcsb pdb:6CMO|rcsb pdb:5BU7|rcsb pdb:4U9E|refseq:WP_001232240.1|rcsb pdb:6C1Q|rcsb pdb:6C1R|rcsb pdb:6D32|rcsb pdb:6D35|rcsb pdb:6UR8|rcsb pdb:6USF|rcsb pdb:5JTB|rcsb pdb:5UVI|rcsb pdb:5K2C|rcsb pdb:5K2D|rcsb pdb:5L31|rcsb pdb:5L32|rcsb pdb:5TVN|rcsb pdb:5OLG|rcsb pdb:5OLH|rcsb pdb:5OLO|rcsb pdb:5OLV|rcsb pdb:5OLZ|rcsb pdb:5OM1|rcsb pdb:5OM4|rcsb pdb:5VRA|rcsb pdb:5XZI|rcsb pdb:5XZJ|rcsb pdb:6AQF|rcsb pdb:6B73|rcsb pdb:5UIG|rcsb pdb:5UNF|rcsb pdb:5UNG|rcsb pdb:5UNH|rcsb pdb:5NDD|rcsb pdb:5NDZ|rcsb pdb:5NJ6|rcsb pdb:5DHH|rcsb pdb:5MZJ|rcsb pdb:5MZP|rcsb pdb:5N2R|rcsb pdb:5N2S|rcsb pdb:5TUD|rcsb pdb:5NLX|rcsb pdb:5NM2|rcsb pdb:5NM4|rcsb pdb:5YM7|rcsb pdb:5XJM|rcsb pdb:6DHY|rcsb pdb:6DHZ|rcsb pdb:6DRX|rcsb pdb:6DRY|rcsb pdb:6DRZ|rcsb pdb:6DS0|rcsb pdb:6A93|rcsb pdb:6A94|rcsb pdb:6CBV|rcsb pdb:6AI5|rcsb pdb:6JZH|rcsb pdb:6PS7|rcsb pdb:6RZ4|rcsb pdb:6RZ5|rcsb pdb:6IQL|rcsb pdb:6JOD|rcsb pdb:6RZ6|rcsb pdb:6RZ7|rcsb pdb:6RZ8|rcsb pdb:6RZ9|rcsb pdb:6KO5|rcsb pdb:6WW2|rcsb pdb:6WWZ|rcsb pdb:7BW0|rcsb pdb:7C61|rcsb pdb:7C6A|rcsb pdb:6WGT|rcsb pdb:6WH4|rcsb pdb:6WHA|rcsb pdb:6WYU|rcsb pdb:6WZ0|rcsb pdb:6WZ1|rcsb pdb:6WZ2|rcsb pdb:6WZ3|rcsb pdb:6WZ7|rcsb pdb:6WZA|rcsb pdb:6WZC|rcsb pdb:6X7E|rcsb pdb:6X8X|rcsb pdb:6ZDR|rcsb pdb:6ZDV refseq:NP_776497.1|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0007191"(adenylate cyclase-activating dopamine receptor signaling pathway)|go:"GO:0016020"(membrane)|go:"GO:0031680"(G-protein beta/gamma-subunit complex)|go:"GO:0031681"(G-protein beta-subunit binding)|go:"GO:0071380"(cellular response to prostaglandin E stimulus)|go:"GO:0071870"(cellular response to catecholamine stimulus)|interpro:IPR001770(G-protein, gamma subunit)|interpro:IPR015898(G-protein, gamma-like subunit)|interpro:IPR036284|rcsb pdb:1GG2|rcsb pdb:1GP2|rcsb pdb:1OMW|rcsb pdb:1XHM|rcsb pdb:2BCJ|rcsb pdb:3AH8|rcsb pdb:3CIK|rcsb pdb:3KRW|rcsb pdb:3KRX|rcsb pdb:3SN6|rcsb pdb:3UZS|rcsb pdb:3V5W|rcsb pdb:4MK0|rcsb pdb:4PNK|rcsb pdb:5TDH|rcsb pdb:5VAI|rcsb pdb:5WG3|rcsb pdb:5WG4|rcsb pdb:5WG5|rcsb pdb:6C2Y|rcsb pdb:6CMO|rcsb pdb:6LPB|rcsb pdb:6NBF|rcsb pdb:6NBH|rcsb pdb:6NBI|rcsb pdb:6PCV|rcsb pdb:6U7C|rcsb pdb:7BW0|rcsb pdb:7BZ2|rcsb pdb:7CZ5|rcsb pdb:7D3S|rcsb pdb:7D68|rcsb pdb:7DHI|rcsb pdb:7DHR|rcsb pdb:7JJO|rcsb pdb:3PSC|rcsb pdb:3PVU|rcsb pdb:3PVW|rcsb pdb:7LJC|rcsb pdb:7LJD|reactome:R-BTA-392170|reactome:R-BTA-416476|reactome:R-BTA-418594|reactome:R-BTA-418597|reactome:R-BTA-428930|reactome:R-BTA-456926|reactome:R-BTA-6814122|reactome:R-BTA-392451|ensembl:ENSBTAG00000003043(gene)|ensembl:ENSBTAT00000003959(transcript)|go:"GO:0003924"(GTPase activity)|go:"GO:0005834"(heterotrimeric G-protein complex)|refseq:XP_005211711.1|refseq:XP_010807541.1|dip:DIP-586N - - - figure legend:Extended Data Fig 1a, b|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2020/06/17 2021/04/19 rogid:O9HPXjm/UQpqt+WPfwjDOEx8+m4562 rogid:8asTjDtSU6sCPSMwcXMbV340Rt49913 rigid:byUWCYFrBR1Dh68SItQ8WMUKU8E false - - 1 1 psi-mi:"MI:0396"(predetermined participant)|psi-mi:"MI:2287"(identification by structure determination) psi-mi:"MI:0396"(predetermined participant)|psi-mi:"MI:2287"(identification by structure determination) uniprotkb:P0ABE7 uniprotkb:P63096 intact:EBI-1120486|uniprotkb:P00192|uniprotkb:P76805|uniprotkb:Q8XCE3 intact:EBI-618639|ensembl:ENSP00000497051|ensembl:ENSP00000497179|ensembl:ENSP00000497260|ensembl:ENSP00000497315|ensembl:ENSP00000497379|ensembl:ENSP00000497717|ensembl:ENSP00000497754|ensembl:ENSP00000497760|ensembl:ENSP00000497765|ensembl:ENSP00000497773|ensembl:ENSP00000498091|ensembl:ENSP00000343027|ensembl:ENSP00000391439|ensembl:ENSP00000496800|ensembl:ENSP00000496829|uniprotkb:P04898|uniprotkb:P11015|uniprotkb:P31871|uniprotkb:Q5U074|uniprotkb:Q8TAN5|uniprotkb:Q9UGA4|uniprotkb:A8KA88|uniprotkb:B4E2V1|uniprotkb:C9J3A4 psi-mi:c562_ecolx(display_long)|uniprotkb:cybC(gene name)|psi-mi:cybC(display_short) psi-mi:gnai1_human(display_long)|uniprotkb:GNAI1(gene name)|psi-mi:GNAI1(display_short)|uniprotkb:Adenylate cyclase-inhibiting G alpha protein(gene name synonym) psi-mi:"MI:0071"(molecular sieving) Kang et al. (2018) pubmed:29899450|imex:IM-28379 taxid:562(ecolx)|taxid:562(Escherichia coli) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0465"(DIP) intact:EBI-25681765|imex:IM-28379-3 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) rcsb pdb:3M4C|rcsb pdb:3M79|rcsb pdb:3NMI|rcsb pdb:3NMJ|rcsb pdb:3NMK|rcsb pdb:3TOL|rcsb pdb:3TOM|rcsb pdb:4IAQ|rcsb pdb:3U8P|rcsb pdb:4PXZ|rcsb pdb:4PY0|rcsb pdb:5DHG|rcsb pdb:4RWA|rcsb pdb:4RWD|rcsb pdb:4U9D|rcsb pdb:4L6R|rcsb pdb:4N6H|rcsb pdb:4NC3|rcsb pdb:5YO4|rcsb pdb:5YO5|rcsb pdb:5YO6|rcsb pdb:4QIM|rcsb pdb:4QIN|interpro:IPR009155(Cytochrome b562)|interpro:IPR010980(Cytochrome c and b562)|rcsb pdb:1APC|rcsb pdb:1LM3|rcsb pdb:1M6T|rcsb pdb:1QPU|rcsb pdb:1QQ3|rcsb pdb:256B|rcsb pdb:2BC5|rcsb pdb:2QLA|rcsb pdb:3C62|rcsb pdb:3C63|rcsb pdb:3DE8|rcsb pdb:3DE9|rcsb pdb:3FOO|rcsb pdb:3FOP|rcsb pdb:3HNI|rcsb pdb:3HNJ|rcsb pdb:4Z34|rcsb pdb:4Z35|rcsb pdb:4Z36|rcsb pdb:3HNK|rcsb pdb:3HNL|rcsb pdb:3IQ5|rcsb pdb:3IQ6|rcsb pdb:3L1M|rcsb pdb:3M15|rcsb pdb:3M4B|rcsb pdb:6BQG|rcsb pdb:6BQH|rcsb pdb:6AK3|rcsb pdb:6G7O|rcsb pdb:6IIU|rcsb pdb:6IIV|go:"GO:0005506"(iron ion binding)|go:"GO:0009055"(electron transfer activity)|go:"GO:0020037"(heme binding)|go:"GO:0042597"(periplasmic space)|rcsb pdb:6LPJ|rcsb pdb:6LPK|rcsb pdb:6LPL|rcsb pdb:6WQA|rcsb pdb:7DFP|rcsb pdb:6ME6|rcsb pdb:6ME7|rcsb pdb:6ME8|rcsb pdb:6ME9|rcsb pdb:6MH8|rcsb pdb:4ZUD|rcsb pdb:5AWI|rcsb pdb:5YO3|rcsb pdb:6DY4|rcsb pdb:6DY6|rcsb pdb:6DY8|rcsb pdb:6DYB|rcsb pdb:6DYC|rcsb pdb:6DYD|rcsb pdb:6DYE|rcsb pdb:6DYF|rcsb pdb:6DYG|rcsb pdb:6DYH|rcsb pdb:6DYI|rcsb pdb:6DYJ|rcsb pdb:6DYK|rcsb pdb:6DYL|rcsb pdb:6M97|rcsb pdb:6M98|rcsb pdb:5UEN|rcsb pdb:4EIY|rcsb pdb:4IAR|rcsb pdb:4IB4|rcsb pdb:4JE9|rcsb pdb:4JEA|rcsb pdb:4JEB|rcsb pdb:4YAY|rcsb pdb:4EA3|rcsb pdb:7JVR|rcsb pdb:4JKV|rcsb pdb:6GT3|rcsb pdb:6S0Q|rcsb pdb:5WIU|rcsb pdb:5WIV|rcsb pdb:6LW5|rcsb pdb:6OS0|rcsb pdb:6OS1|rcsb pdb:6OS2|rcsb pdb:6OT4|rcsb pdb:6OT7|rcsb pdb:6OT8|rcsb pdb:6OT9|rcsb pdb:6OVH|rcsb pdb:4O9R|rcsb pdb:5IU4|rcsb pdb:5IU7|rcsb pdb:5IU8|rcsb pdb:5IUA|rcsb pdb:5IUB|rcsb pdb:5K2A|rcsb pdb:5K2B|rcsb pdb:5L7D|rcsb pdb:5L7I|rcsb pdb:7ARO|rcsb pdb:7CMU|rcsb pdb:7CMV|rcsb pdb:7E2X|rcsb pdb:7E2Y|rcsb pdb:7E2Z|rcsb pdb:7E32|rcsb pdb:7E33|rcsb pdb:7KOO|rcsb pdb:7KOQ|rcsb pdb:7KOX|rcsb pdb:4NTJ|rcsb pdb:4OR2|rcsb pdb:6DO1|rcsb pdb:6CC4|rcsb pdb:6CMO|rcsb pdb:5BU7|rcsb pdb:4U9E|refseq:WP_001232240.1|rcsb pdb:6C1Q|rcsb pdb:6C1R|rcsb pdb:6D32|rcsb pdb:6D35|rcsb pdb:6UR8|rcsb pdb:6USF|rcsb pdb:5JTB|rcsb pdb:5UVI|rcsb pdb:5K2C|rcsb pdb:5K2D|rcsb pdb:5L31|rcsb pdb:5L32|rcsb pdb:5TVN|rcsb pdb:5OLG|rcsb pdb:5OLH|rcsb pdb:5OLO|rcsb pdb:5OLV|rcsb pdb:5OLZ|rcsb pdb:5OM1|rcsb pdb:5OM4|rcsb pdb:5VRA|rcsb pdb:5XZI|rcsb pdb:5XZJ|rcsb pdb:6AQF|rcsb pdb:6B73|rcsb pdb:5UIG|rcsb pdb:5UNF|rcsb pdb:5UNG|rcsb pdb:5UNH|rcsb pdb:5NDD|rcsb pdb:5NDZ|rcsb pdb:5NJ6|rcsb pdb:5DHH|rcsb pdb:5MZJ|rcsb pdb:5MZP|rcsb pdb:5N2R|rcsb pdb:5N2S|rcsb pdb:5TUD|rcsb pdb:5NLX|rcsb pdb:5NM2|rcsb pdb:5NM4|rcsb pdb:5YM7|rcsb pdb:5XJM|rcsb pdb:6DHY|rcsb pdb:6DHZ|rcsb pdb:6DRX|rcsb pdb:6DRY|rcsb pdb:6DRZ|rcsb pdb:6DS0|rcsb pdb:6A93|rcsb pdb:6A94|rcsb pdb:6CBV|rcsb pdb:6AI5|rcsb pdb:6JZH|rcsb pdb:6PS7|rcsb pdb:6RZ4|rcsb pdb:6RZ5|rcsb pdb:6IQL|rcsb pdb:6JOD|rcsb pdb:6RZ6|rcsb pdb:6RZ7|rcsb pdb:6RZ8|rcsb pdb:6RZ9|rcsb pdb:6KO5|rcsb pdb:6WW2|rcsb pdb:6WWZ|rcsb pdb:7BW0|rcsb pdb:7C61|rcsb pdb:7C6A|rcsb pdb:6WGT|rcsb pdb:6WH4|rcsb pdb:6WHA|rcsb pdb:6WYU|rcsb pdb:6WZ0|rcsb pdb:6WZ1|rcsb pdb:6WZ2|rcsb pdb:6WZ3|rcsb pdb:6WZ7|rcsb pdb:6WZA|rcsb pdb:6WZC|rcsb pdb:6X7E|rcsb pdb:6X8X|rcsb pdb:6ZDR|rcsb pdb:6ZDV reactome:R-HSA-418597|reactome:R-HSA-422356|reactome:R-HSA-9009391|reactome:R-HSA-9660821|reactome:R-HSA-418594|ensembl:ENST00000351004(transcript)|ensembl:ENST00000442586(transcript)|ensembl:ENST00000648098(transcript)|ensembl:ENSG00000127955(gene)|ensembl:ENST00000648306(transcript)|ensembl:ENST00000648412(transcript)|ensembl:ENST00000648476(transcript)|ensembl:ENST00000648663(transcript)|ensembl:ENST00000648832(transcript)|ensembl:ENST00000648877(transcript)|ensembl:ENST00000648953(transcript)|ensembl:ENST00000649225(transcript)|ensembl:ENST00000649267(transcript)|ensembl:ENST00000649487(transcript)|ensembl:ENST00000649796(transcript)|ensembl:ENST00000649855(transcript)|go:"GO:0000287"(magnesium ion binding)|go:"GO:0001664"(G protein-coupled receptor binding)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005813"(centrosome)|go:"GO:0005834"(heterotrimeric G-protein complex)|go:"GO:0005886"(plasma membrane)|go:"GO:0007049"(cell cycle)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0007188"(adenylate cyclase-modulating G protein-coupled receptor signaling pathway)|go:"GO:0007193"(adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway)|go:"GO:0019003"(GDP binding)|go:"GO:0030496"(midbody)|go:"GO:0031683"(G-protein beta/gamma-subunit complex binding)|go:"GO:0031821"(G protein-coupled serotonin receptor binding)|go:"GO:0032794"(GTPase activating protein binding)|go:"GO:0043434"(response to peptide hormone)|go:"GO:0043949"(regulation of cAMP-mediated signaling)|go:"GO:0045121"(membrane raft)|go:"GO:0050805"(negative regulation of synaptic transmission)|go:"GO:0051301"(cell division)|go:"GO:0060236"(regulation of mitotic spindle organization)|go:"GO:0070062"(extracellular exosome)|go:"GO:0099738"(cell cortex region)|go:"GO:1904322"(cellular response to forskolin)|go:"GO:1904778"(positive regulation of protein localization to cell cortex)|interpro:IPR001019("Guanine nucleotide binding protein (G-protein), alpha subunit")|interpro:IPR001408(G-protein alpha subunit, group I)|interpro:IPR011025(G protein alpha subunit, helical insertion)|interpro:IPR027417|mint:P63096|rcsb pdb:1KJY|rcsb pdb:1Y3A|rcsb pdb:2G83|rcsb pdb:2GTP|rcsb pdb:2IK8|rcsb pdb:2OM2|rcsb pdb:2XNS|rcsb pdb:3ONW|rcsb pdb:3QE0|rcsb pdb:3QI2|rcsb pdb:3UMR|rcsb pdb:3UMS|rcsb pdb:4G5Q|rcsb pdb:5JS7|rcsb pdb:5JS8|rcsb pdb:5TDH|rcsb pdb:6CMO|rcsb pdb:6CRK|rcsb pdb:6DDE|rcsb pdb:6DDF|rcsb pdb:6KPF|rcsb pdb:6KPG|rcsb pdb:6LFM|rcsb pdb:6LFO|rcsb pdb:6LML|rcsb pdb:6N4B|rcsb pdb:6OMM|rcsb pdb:6OS9|rcsb pdb:6OSA|rcsb pdb:6OT0|rcsb pdb:6PB0|rcsb pdb:6PB1|rcsb pdb:6PT0|rcsb pdb:6QNO|rcsb pdb:6VU8|rcsb pdb:6XBJ|rcsb pdb:6XBK|rcsb pdb:6XBL|rcsb pdb:6XBM|rcsb pdb:7CMU|rcsb pdb:7CMV|rcsb pdb:7E2X|rcsb pdb:7E2Y|rcsb pdb:7E2Z|rcsb pdb:7E32|rcsb pdb:7E33|rcsb pdb:7E9G|rcsb pdb:7EB2|rcsb pdb:7JVR|rcsb pdb:7L0P|rcsb pdb:7L0Q|rcsb pdb:7L0R|rcsb pdb:7L0S|rcsb pdb:7O7F|reactome:R-HSA-170670|reactome:R-HSA-392170|reactome:R-HSA-400042|reactome:R-HSA-418555|refseq:NP_002060.4|refseq:NP_001243343.1 - - - figure legend:Extended Data Fig 1a, b|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2020/06/17 2021/04/19 rogid:O9HPXjm/UQpqt+WPfwjDOEx8+m4562 rogid:3yQOCXJb8Undp/Xw42xrBiG5ePE9606 rigid:byUWCYFrBR1Dh68SItQ8WMUKU8E false - - 1 1 psi-mi:"MI:0396"(predetermined participant)|psi-mi:"MI:2287"(identification by structure determination) psi-mi:"MI:0396"(predetermined participant)|psi-mi:"MI:2287"(identification by structure determination)