#ID(s) interactor A ID(s) interactor B Alt. ID(s) interactor A Alt. ID(s) interactor B Alias(es) interactor A Alias(es) interactor B Interaction detection method(s) Publication 1st author(s) Publication Identifier(s) Taxid interactor A Taxid interactor B Interaction type(s) Source database(s) Interaction identifier(s) Confidence value(s) Expansion method(s) Biological role(s) interactor A Biological role(s) interactor B Experimental role(s) interactor A Experimental role(s) interactor B Type(s) interactor A Type(s) interactor B Xref(s) interactor A Xref(s) interactor B Interaction Xref(s) Annotation(s) interactor A Annotation(s) interactor B Interaction annotation(s) Host organism(s) Interaction parameter(s) Creation date Update date Checksum(s) interactor A Checksum(s) interactor B Interaction Checksum(s) Negative Feature(s) interactor A Feature(s) interactor B Stoichiometry(s) interactor A Stoichiometry(s) interactor B Identification method participant A Identification method participant B uniprotkb:Q9BXW6 uniprotkb:Q8NHP6 intact:EBI-765918|uniprotkb:Q9BZF5|uniprotkb:Q9NW87|uniprotkb:B7Z7D3|ensembl:ENSP00000320291 intact:EBI-2812848|uniprotkb:Q8NA83|uniprotkb:Q8N3H2|ensembl:ENSP00000369860 psi-mi:osbl1_human(display_long)|uniprotkb:OSBPL1A(gene name)|psi-mi:OSBPL1A(display_short)|uniprotkb:ORP1(gene name synonym)|uniprotkb:OSBP8(gene name synonym)|uniprotkb:OSBPL1(gene name synonym)|uniprotkb:OSBPL1B(gene name synonym) psi-mi:mspd2_human(display_long)|uniprotkb:MOSPD2(gene name)|psi-mi:MOSPD2(display_short) psi-mi:"MI:0096"(pull down) Di et al. (2018) pubmed:29858488|imex:IM-28178 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-25616876|imex:IM-28178-21 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001229437.1|refseq:NP_060500.3|refseq:NP_542164.2|refseq:XP_016881022.1|ensembl:ENSG00000141447(gene)|ensembl:ENST00000319481(transcript)|go:"GO:0005543"(phospholipid binding)|go:"GO:0005768"(endosome)|go:"GO:0005770"(late endosome)|go:"GO:0005829"(cytosol)|go:"GO:0006699"(bile acid biosynthetic process)|go:"GO:0008203"(cholesterol metabolic process)|go:"GO:0015248"(sterol transporter activity)|go:"GO:0015485"(cholesterol binding)|go:"GO:0016020"(membrane)|go:"GO:0016192"(vesicle-mediated transport)|go:"GO:0032934"(sterol binding)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0044232"(organelle membrane contact site)|go:"GO:0070062"(extracellular exosome)|interpro:IPR000648(Oxysterol-binding protein)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR002110(Ankyrin)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR018494|interpro:IPR020683|interpro:IPR036770|interpro:IPR037239|mint:Q9BXW6|rcsb pdb:5ZM5|rcsb pdb:5ZM6|rcsb pdb:5ZM7|rcsb pdb:6IYB|rcsb pdb:6TQS|reactome:R-HSA-192105|reactome:R-HSA-2132295|refseq:XP_016881023.1 refseq:NP_001170946.1|refseq:NP_689794.1|go:"GO:0090023"(positive regulation of neutrophil chemotaxis)|go:"GO:0090026"(positive regulation of monocyte chemotaxis)|go:"GO:0140284"(endoplasmic reticulum-endosome membrane contact site)|interpro:IPR000535(Major sperm protein)|interpro:IPR001251(Cellular retinaldehyde-binding/triple function, C-terminal)|interpro:IPR008962(PapD-like)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR036273|interpro:IPR036865|mint:Q8NHP6|rcsb pdb:6TQS|rcsb pdb:6TQT|rcsb pdb:6TQU|reactome:R-HSA-6798695|reactome:R-HSA-9013405|ensembl:ENSG00000130150(gene)|ensembl:ENST00000380492(transcript)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006935"(chemotaxis)|go:"GO:0016020"(membrane)|go:"GO:0035579"(specific granule membrane)|go:"GO:0044232"(organelle membrane contact site) - - - figure legend:Fig.1A-C|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2020/05/21 2020/05/21 rogid:IaZi6kaj9t0aU94PF/XOaxH1dNA9606 rogid:WEdwMYKpu1uQll5NXnMm4P51R4E9606 rigid:R2vVk/XSQ6zBe0HIpfgnF/ngW/8 false sufficient binding region:469-485|biotin tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9BXW6 uniprotkb:O95292 intact:EBI-765918|uniprotkb:Q9BZF5|uniprotkb:Q9NW87|uniprotkb:B7Z7D3|ensembl:ENSP00000320291 intact:EBI-1188298|uniprotkb:O95293|uniprotkb:Q9P0H0|uniprotkb:A2A2F2|ensembl:ENSP00000417175 psi-mi:osbl1_human(display_long)|uniprotkb:OSBPL1A(gene name)|psi-mi:OSBPL1A(display_short)|uniprotkb:ORP1(gene name synonym)|uniprotkb:OSBP8(gene name synonym)|uniprotkb:OSBPL1(gene name synonym)|uniprotkb:OSBPL1B(gene name synonym) psi-mi:vapb_human(display_long)|uniprotkb:VAPB(gene name)|psi-mi:VAPB(display_short)|uniprotkb:UNQ484/PRO983(orf name) psi-mi:"MI:0096"(pull down) Di et al. (2018) pubmed:29858488|imex:IM-28178 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-25616876|imex:IM-28178-21 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001229437.1|refseq:NP_060500.3|refseq:NP_542164.2|refseq:XP_016881022.1|ensembl:ENSG00000141447(gene)|ensembl:ENST00000319481(transcript)|go:"GO:0005543"(phospholipid binding)|go:"GO:0005768"(endosome)|go:"GO:0005770"(late endosome)|go:"GO:0005829"(cytosol)|go:"GO:0006699"(bile acid biosynthetic process)|go:"GO:0008203"(cholesterol metabolic process)|go:"GO:0015248"(sterol transporter activity)|go:"GO:0015485"(cholesterol binding)|go:"GO:0016020"(membrane)|go:"GO:0016192"(vesicle-mediated transport)|go:"GO:0032934"(sterol binding)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0044232"(organelle membrane contact site)|go:"GO:0070062"(extracellular exosome)|interpro:IPR000648(Oxysterol-binding protein)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR002110(Ankyrin)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR018494|interpro:IPR020683|interpro:IPR036770|interpro:IPR037239|mint:Q9BXW6|rcsb pdb:5ZM5|rcsb pdb:5ZM6|rcsb pdb:5ZM7|rcsb pdb:6IYB|rcsb pdb:6TQS|reactome:R-HSA-192105|reactome:R-HSA-2132295|refseq:XP_016881023.1 refseq:NP_001182606.1|refseq:NP_004729.1|ensembl:ENSG00000124164(gene)|ensembl:ENST00000475243(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0006874"(cellular calcium ion homeostasis)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0007029"(endoplasmic reticulum organization)|go:"GO:0008017"(microtubule binding)|go:"GO:0016021"(integral component of membrane)|go:"GO:0019048"(modulation by virus of host process)|go:"GO:0019899"(enzyme binding)|go:"GO:0030968"(endoplasmic reticulum unfolded protein response)|go:"GO:0033149"(FFAT motif binding)|go:"GO:0036498"(IRE1-mediated unfolded protein response)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0044790"(suppression of viral release by host)|go:"GO:0044791"(obsolete positive regulation by host of viral release from host cell)|go:"GO:0044828"(negative regulation by host of viral genome replication)|go:"GO:0044829"(positive regulation by host of viral genome replication)|go:"GO:0044830"(modulation by host of viral RNA genome replication)|go:"GO:0045070"(positive regulation of viral genome replication)|go:"GO:0045296"(cadherin binding)|go:"GO:0046725"(negative regulation by virus of viral protein levels in host cell)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0048487"(beta-tubulin binding)|go:"GO:0061817"(endoplasmic reticulum-plasma membrane tethering)|go:"GO:0090114"(COPII-coated vesicle budding)|go:"GO:0090158"(endoplasmic reticulum membrane organization)|interpro:IPR000535(Major sperm protein)|interpro:IPR008962(PapD-like)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR016763(Vesicle-associated membrane protein)|mint:O95292|rcsb pdb:2MDK|rcsb pdb:3IKK|reactome:R-HSA-1660661|reactome:R-HSA-8980692|reactome:R-HSA-9013106|reactome:R-HSA-9013404|reactome:R-HSA-9013405|reactome:R-HSA-9013408|dip:DIP-39816N - - - figure legend:Fig.1A-C|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2020/05/21 2020/05/21 rogid:IaZi6kaj9t0aU94PF/XOaxH1dNA9606 rogid:+TuApjAmnGF1UZonXIsrPaIN4Ak9606 rigid:R2vVk/XSQ6zBe0HIpfgnF/ngW/8 false sufficient binding region:469-485|biotin tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9BXW6 uniprotkb:Q9P0L0 intact:EBI-765918|uniprotkb:Q9BZF5|uniprotkb:Q9NW87|uniprotkb:B7Z7D3|ensembl:ENSP00000320291 intact:EBI-1059156|uniprotkb:Q9UBZ2|uniprotkb:O75453|uniprotkb:Q5U0E7|intact:EBI-2556404|uniprotkb:A6NDZ0|intact:EBI-2512000|uniprotkb:D3DUI3|ensembl:ENSP00000382880 psi-mi:osbl1_human(display_long)|uniprotkb:OSBPL1A(gene name)|psi-mi:OSBPL1A(display_short)|uniprotkb:ORP1(gene name synonym)|uniprotkb:OSBP8(gene name synonym)|uniprotkb:OSBPL1(gene name synonym)|uniprotkb:OSBPL1B(gene name synonym) psi-mi:vapa_human(display_long)|uniprotkb:VAPA(gene name)|psi-mi:VAPA(display_short)|uniprotkb:VAP33(gene name synonym)|uniprotkb:33 kDa VAMP-associated protein(gene name synonym) psi-mi:"MI:0096"(pull down) Di et al. (2018) pubmed:29858488|imex:IM-28178 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-25616876|imex:IM-28178-21 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001229437.1|refseq:NP_060500.3|refseq:NP_542164.2|refseq:XP_016881022.1|ensembl:ENSG00000141447(gene)|ensembl:ENST00000319481(transcript)|go:"GO:0005543"(phospholipid binding)|go:"GO:0005768"(endosome)|go:"GO:0005770"(late endosome)|go:"GO:0005829"(cytosol)|go:"GO:0006699"(bile acid biosynthetic process)|go:"GO:0008203"(cholesterol metabolic process)|go:"GO:0015248"(sterol transporter activity)|go:"GO:0015485"(cholesterol binding)|go:"GO:0016020"(membrane)|go:"GO:0016192"(vesicle-mediated transport)|go:"GO:0032934"(sterol binding)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0044232"(organelle membrane contact site)|go:"GO:0070062"(extracellular exosome)|interpro:IPR000648(Oxysterol-binding protein)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR002110(Ankyrin)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR018494|interpro:IPR020683|interpro:IPR036770|interpro:IPR037239|mint:Q9BXW6|rcsb pdb:5ZM5|rcsb pdb:5ZM6|rcsb pdb:5ZM7|rcsb pdb:6IYB|rcsb pdb:6TQS|reactome:R-HSA-192105|reactome:R-HSA-2132295|refseq:XP_016881023.1 refseq:NP_003565.4|refseq:NP_919415.2|dip:DIP-41135N|go:"GO:0031982"(vesicle)|go:"GO:0033149"(FFAT motif binding)|go:"GO:0035577"(azurophil granule membrane)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0044791"(obsolete positive regulation by host of viral release from host cell)|go:"GO:0044828"(negative regulation by host of viral genome replication)|go:"GO:0044829"(positive regulation by host of viral genome replication)|go:"GO:0045296"(cadherin binding)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0061025"(membrane fusion)|go:"GO:0070972"(protein localization to endoplasmic reticulum)|go:"GO:0090114"(COPII-coated vesicle budding)|interpro:IPR000535(Major sperm protein)|interpro:IPR008962(PapD-like)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR016763(Vesicle-associated membrane protein)|mint:Q9P0L0|rcsb pdb:2RR3|rcsb pdb:6TQR|reactome:R-HSA-1660661|reactome:R-HSA-6798695|reactome:R-HSA-9609523|ensembl:ENSG00000101558(gene)|ensembl:ENST00000400000(transcript)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0031175"(neuron projection development)|go:"GO:0031965"(nuclear membrane)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005923"(bicellular tight junction)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0008017"(microtubule binding)|go:"GO:0008219"(cell death)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0016021"(integral component of membrane) - - - figure legend:Fig.1A-C|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2020/05/21 2020/05/21 rogid:IaZi6kaj9t0aU94PF/XOaxH1dNA9606 rogid:h8NG5Ak0n6b/iq2yKYMsLsJKpos9606 rigid:R2vVk/XSQ6zBe0HIpfgnF/ngW/8 false sufficient binding region:469-485|biotin tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9BXW6 uniprotkb:Q8NHP6 intact:EBI-765918|uniprotkb:Q9BZF5|uniprotkb:Q9NW87|uniprotkb:B7Z7D3|ensembl:ENSP00000320291 intact:EBI-2812848|uniprotkb:Q8NA83|uniprotkb:Q8N3H2|ensembl:ENSP00000369860 psi-mi:osbl1_human(display_long)|uniprotkb:OSBPL1A(gene name)|psi-mi:OSBPL1A(display_short)|uniprotkb:ORP1(gene name synonym)|uniprotkb:OSBP8(gene name synonym)|uniprotkb:OSBPL1(gene name synonym)|uniprotkb:OSBPL1B(gene name synonym) psi-mi:mspd2_human(display_long)|uniprotkb:MOSPD2(gene name)|psi-mi:MOSPD2(display_short) psi-mi:"MI:0096"(pull down) Di et al. (2018) pubmed:29858488|imex:IM-28178 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-25616941|imex:IM-28178-23 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001229437.1|refseq:NP_060500.3|refseq:NP_542164.2|refseq:XP_016881022.1|ensembl:ENSG00000141447(gene)|ensembl:ENST00000319481(transcript)|go:"GO:0005543"(phospholipid binding)|go:"GO:0005768"(endosome)|go:"GO:0005770"(late endosome)|go:"GO:0005829"(cytosol)|go:"GO:0006699"(bile acid biosynthetic process)|go:"GO:0008203"(cholesterol metabolic process)|go:"GO:0015248"(sterol transporter activity)|go:"GO:0015485"(cholesterol binding)|go:"GO:0016020"(membrane)|go:"GO:0016192"(vesicle-mediated transport)|go:"GO:0032934"(sterol binding)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0044232"(organelle membrane contact site)|go:"GO:0070062"(extracellular exosome)|interpro:IPR000648(Oxysterol-binding protein)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR002110(Ankyrin)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR018494|interpro:IPR020683|interpro:IPR036770|interpro:IPR037239|mint:Q9BXW6|rcsb pdb:5ZM5|rcsb pdb:5ZM6|rcsb pdb:5ZM7|rcsb pdb:6IYB|rcsb pdb:6TQS|reactome:R-HSA-192105|reactome:R-HSA-2132295|refseq:XP_016881023.1 refseq:NP_001170946.1|refseq:NP_689794.1|go:"GO:0090023"(positive regulation of neutrophil chemotaxis)|go:"GO:0090026"(positive regulation of monocyte chemotaxis)|go:"GO:0140284"(endoplasmic reticulum-endosome membrane contact site)|interpro:IPR000535(Major sperm protein)|interpro:IPR001251(Cellular retinaldehyde-binding/triple function, C-terminal)|interpro:IPR008962(PapD-like)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR036273|interpro:IPR036865|mint:Q8NHP6|rcsb pdb:6TQS|rcsb pdb:6TQT|rcsb pdb:6TQU|reactome:R-HSA-6798695|reactome:R-HSA-9013405|ensembl:ENSG00000130150(gene)|ensembl:ENST00000380492(transcript)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006935"(chemotaxis)|go:"GO:0016020"(membrane)|go:"GO:0035579"(specific granule membrane)|go:"GO:0044232"(organelle membrane contact site) - - - figure legend:Fig.1E|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2020/05/21 2020/05/21 rogid:IaZi6kaj9t0aU94PF/XOaxH1dNA9606 rogid:WEdwMYKpu1uQll5NXnMm4P51R4E9606 rigid:R2vVk/XSQ6zBe0HIpfgnF/ngW/8 false sufficient binding region:469-485|biotin tag:n-n - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:Q9BXW6 uniprotkb:O95292 intact:EBI-765918|uniprotkb:Q9BZF5|uniprotkb:Q9NW87|uniprotkb:B7Z7D3|ensembl:ENSP00000320291 intact:EBI-1188298|uniprotkb:O95293|uniprotkb:Q9P0H0|uniprotkb:A2A2F2|ensembl:ENSP00000417175 psi-mi:osbl1_human(display_long)|uniprotkb:OSBPL1A(gene name)|psi-mi:OSBPL1A(display_short)|uniprotkb:ORP1(gene name synonym)|uniprotkb:OSBP8(gene name synonym)|uniprotkb:OSBPL1(gene name synonym)|uniprotkb:OSBPL1B(gene name synonym) psi-mi:vapb_human(display_long)|uniprotkb:VAPB(gene name)|psi-mi:VAPB(display_short)|uniprotkb:UNQ484/PRO983(orf name) psi-mi:"MI:0096"(pull down) Di et al. (2018) pubmed:29858488|imex:IM-28178 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-25616941|imex:IM-28178-23 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001229437.1|refseq:NP_060500.3|refseq:NP_542164.2|refseq:XP_016881022.1|ensembl:ENSG00000141447(gene)|ensembl:ENST00000319481(transcript)|go:"GO:0005543"(phospholipid binding)|go:"GO:0005768"(endosome)|go:"GO:0005770"(late endosome)|go:"GO:0005829"(cytosol)|go:"GO:0006699"(bile acid biosynthetic process)|go:"GO:0008203"(cholesterol metabolic process)|go:"GO:0015248"(sterol transporter activity)|go:"GO:0015485"(cholesterol binding)|go:"GO:0016020"(membrane)|go:"GO:0016192"(vesicle-mediated transport)|go:"GO:0032934"(sterol binding)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0044232"(organelle membrane contact site)|go:"GO:0070062"(extracellular exosome)|interpro:IPR000648(Oxysterol-binding protein)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR002110(Ankyrin)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR018494|interpro:IPR020683|interpro:IPR036770|interpro:IPR037239|mint:Q9BXW6|rcsb pdb:5ZM5|rcsb pdb:5ZM6|rcsb pdb:5ZM7|rcsb pdb:6IYB|rcsb pdb:6TQS|reactome:R-HSA-192105|reactome:R-HSA-2132295|refseq:XP_016881023.1 refseq:NP_001182606.1|refseq:NP_004729.1|ensembl:ENSG00000124164(gene)|ensembl:ENST00000475243(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0006874"(cellular calcium ion homeostasis)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0007029"(endoplasmic reticulum organization)|go:"GO:0008017"(microtubule binding)|go:"GO:0016021"(integral component of membrane)|go:"GO:0019048"(modulation by virus of host process)|go:"GO:0019899"(enzyme binding)|go:"GO:0030968"(endoplasmic reticulum unfolded protein response)|go:"GO:0033149"(FFAT motif binding)|go:"GO:0036498"(IRE1-mediated unfolded protein response)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0044790"(suppression of viral release by host)|go:"GO:0044791"(obsolete positive regulation by host of viral release from host cell)|go:"GO:0044828"(negative regulation by host of viral genome replication)|go:"GO:0044829"(positive regulation by host of viral genome replication)|go:"GO:0044830"(modulation by host of viral RNA genome replication)|go:"GO:0045070"(positive regulation of viral genome replication)|go:"GO:0045296"(cadherin binding)|go:"GO:0046725"(negative regulation by virus of viral protein levels in host cell)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0048487"(beta-tubulin binding)|go:"GO:0061817"(endoplasmic reticulum-plasma membrane tethering)|go:"GO:0090114"(COPII-coated vesicle budding)|go:"GO:0090158"(endoplasmic reticulum membrane organization)|interpro:IPR000535(Major sperm protein)|interpro:IPR008962(PapD-like)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR016763(Vesicle-associated membrane protein)|mint:O95292|rcsb pdb:2MDK|rcsb pdb:3IKK|reactome:R-HSA-1660661|reactome:R-HSA-8980692|reactome:R-HSA-9013106|reactome:R-HSA-9013404|reactome:R-HSA-9013405|reactome:R-HSA-9013408|dip:DIP-39816N - - - figure legend:Fig.1E|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2020/05/21 2020/05/21 rogid:IaZi6kaj9t0aU94PF/XOaxH1dNA9606 rogid:+TuApjAmnGF1UZonXIsrPaIN4Ak9606 rigid:R2vVk/XSQ6zBe0HIpfgnF/ngW/8 false sufficient binding region:469-485|biotin tag:n-n - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:Q9BXW6 uniprotkb:Q9P0L0 intact:EBI-765918|uniprotkb:Q9BZF5|uniprotkb:Q9NW87|uniprotkb:B7Z7D3|ensembl:ENSP00000320291 intact:EBI-1059156|uniprotkb:Q9UBZ2|uniprotkb:O75453|uniprotkb:Q5U0E7|intact:EBI-2556404|uniprotkb:A6NDZ0|intact:EBI-2512000|uniprotkb:D3DUI3|ensembl:ENSP00000382880 psi-mi:osbl1_human(display_long)|uniprotkb:OSBPL1A(gene name)|psi-mi:OSBPL1A(display_short)|uniprotkb:ORP1(gene name synonym)|uniprotkb:OSBP8(gene name synonym)|uniprotkb:OSBPL1(gene name synonym)|uniprotkb:OSBPL1B(gene name synonym) psi-mi:vapa_human(display_long)|uniprotkb:VAPA(gene name)|psi-mi:VAPA(display_short)|uniprotkb:VAP33(gene name synonym)|uniprotkb:33 kDa VAMP-associated protein(gene name synonym) psi-mi:"MI:0096"(pull down) Di et al. (2018) pubmed:29858488|imex:IM-28178 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-25616941|imex:IM-28178-23 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001229437.1|refseq:NP_060500.3|refseq:NP_542164.2|refseq:XP_016881022.1|ensembl:ENSG00000141447(gene)|ensembl:ENST00000319481(transcript)|go:"GO:0005543"(phospholipid binding)|go:"GO:0005768"(endosome)|go:"GO:0005770"(late endosome)|go:"GO:0005829"(cytosol)|go:"GO:0006699"(bile acid biosynthetic process)|go:"GO:0008203"(cholesterol metabolic process)|go:"GO:0015248"(sterol transporter activity)|go:"GO:0015485"(cholesterol binding)|go:"GO:0016020"(membrane)|go:"GO:0016192"(vesicle-mediated transport)|go:"GO:0032934"(sterol binding)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0044232"(organelle membrane contact site)|go:"GO:0070062"(extracellular exosome)|interpro:IPR000648(Oxysterol-binding protein)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR002110(Ankyrin)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR018494|interpro:IPR020683|interpro:IPR036770|interpro:IPR037239|mint:Q9BXW6|rcsb pdb:5ZM5|rcsb pdb:5ZM6|rcsb pdb:5ZM7|rcsb pdb:6IYB|rcsb pdb:6TQS|reactome:R-HSA-192105|reactome:R-HSA-2132295|refseq:XP_016881023.1 refseq:NP_003565.4|refseq:NP_919415.2|dip:DIP-41135N|go:"GO:0031982"(vesicle)|go:"GO:0033149"(FFAT motif binding)|go:"GO:0035577"(azurophil granule membrane)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0044791"(obsolete positive regulation by host of viral release from host cell)|go:"GO:0044828"(negative regulation by host of viral genome replication)|go:"GO:0044829"(positive regulation by host of viral genome replication)|go:"GO:0045296"(cadherin binding)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0061025"(membrane fusion)|go:"GO:0070972"(protein localization to endoplasmic reticulum)|go:"GO:0090114"(COPII-coated vesicle budding)|interpro:IPR000535(Major sperm protein)|interpro:IPR008962(PapD-like)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR016763(Vesicle-associated membrane protein)|mint:Q9P0L0|rcsb pdb:2RR3|rcsb pdb:6TQR|reactome:R-HSA-1660661|reactome:R-HSA-6798695|reactome:R-HSA-9609523|ensembl:ENSG00000101558(gene)|ensembl:ENST00000400000(transcript)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0031175"(neuron projection development)|go:"GO:0031965"(nuclear membrane)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005923"(bicellular tight junction)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0008017"(microtubule binding)|go:"GO:0008219"(cell death)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0016021"(integral component of membrane) - - - figure legend:Fig.1E|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2020/05/21 2020/05/21 rogid:IaZi6kaj9t0aU94PF/XOaxH1dNA9606 rogid:h8NG5Ak0n6b/iq2yKYMsLsJKpos9606 rigid:R2vVk/XSQ6zBe0HIpfgnF/ngW/8 false sufficient binding region:469-485|biotin tag:n-n - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:Q8NHP6 uniprotkb:O95772 intact:EBI-2812848|uniprotkb:Q8NA83|uniprotkb:Q8N3H2|ensembl:ENSP00000369860 intact:EBI-3916943|ensembl:ENSP00000009041|ensembl:ENSP00000379334|uniprotkb:A4D1X0 psi-mi:mspd2_human(display_long)|uniprotkb:MOSPD2(gene name)|psi-mi:MOSPD2(display_short) psi-mi:str3n_human(display_long)|uniprotkb:STARD3NL(gene name)|psi-mi:STARD3NL(display_short)|uniprotkb:MENTHO(gene name synonym)|uniprotkb:MLN64 N-terminal domain homolog(gene name synonym)|uniprotkb:UNQ855/PRO1864(orf name) psi-mi:"MI:0096"(pull down) Di et al. (2018) pubmed:29858488|imex:IM-28178 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0486"(UniProt) intact:EBI-25618517|imex:IM-28178-37 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001170946.1|refseq:NP_689794.1|go:"GO:0090023"(positive regulation of neutrophil chemotaxis)|go:"GO:0090026"(positive regulation of monocyte chemotaxis)|go:"GO:0140284"(endoplasmic reticulum-endosome membrane contact site)|interpro:IPR000535(Major sperm protein)|interpro:IPR001251(Cellular retinaldehyde-binding/triple function, C-terminal)|interpro:IPR008962(PapD-like)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR036273|interpro:IPR036865|mint:Q8NHP6|rcsb pdb:6TQS|rcsb pdb:6TQT|rcsb pdb:6TQU|reactome:R-HSA-6798695|reactome:R-HSA-9013405|ensembl:ENSG00000130150(gene)|ensembl:ENST00000380492(transcript)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006935"(chemotaxis)|go:"GO:0016020"(membrane)|go:"GO:0035579"(specific granule membrane)|go:"GO:0044232"(organelle membrane contact site) refseq:XP_011513874.1|refseq:NP_114405.1|ensembl:ENSG00000010270(gene)|ensembl:ENST00000009041(transcript)|ensembl:ENST00000396013(transcript)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005768"(endosome)|go:"GO:0005829"(cytosol)|go:"GO:0015485"(cholesterol binding)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0031902"(late endosome membrane)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0044232"(organelle membrane contact site)|go:"GO:0099044"(vesicle tethering to endoplasmic reticulum)|go:"GO:0140284"(endoplasmic reticulum-endosome membrane contact site)|interpro:IPR019498|reactome:R-HSA-196108|refseq:XP_005249937.1|refseq:XP_016868181.1|refseq:XP_016868182.1|refseq:XP_016868183.1 - - - figure legend:EV. 2C|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2020/05/21 2020/05/21 rogid:WEdwMYKpu1uQll5NXnMm4P51R4E9606 rogid:Ecl/gQNri850hBVjWGP0Dfnk8ns9606 rigid:QhnYtApi6Lv7Q8xIRyl4FI+98x0 false his tag:c-c|sufficient binding region:282-490 necessary binding region:208-213|flag tag:?-?|mutation disrupting interaction strength:208-209 - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:Q8NHP6 uniprotkb:Q14849 intact:EBI-2812848|uniprotkb:Q8NA83|uniprotkb:Q8N3H2|ensembl:ENSP00000369860 intact:EBI-9819324|uniprotkb:A8MXA4|uniprotkb:B4DUY1|uniprotkb:F5H0G2|uniprotkb:Q53Y53|uniprotkb:Q96HM9|ensembl:ENSP00000337446 psi-mi:mspd2_human(display_long)|uniprotkb:MOSPD2(gene name)|psi-mi:MOSPD2(display_short) psi-mi:star3_human(display_long)|uniprotkb:STARD3(gene name)|psi-mi:STARD3(display_short)|uniprotkb:CAB1(gene name synonym)|uniprotkb:MLN64(gene name synonym)|uniprotkb:Metastatic lymph node gene 64 protein(gene name synonym)|uniprotkb:Protein CAB1(gene name synonym)|uniprotkb:START domain-containing protein 3(gene name synonym) psi-mi:"MI:0096"(pull down) Di et al. (2018) pubmed:29858488|imex:IM-28178 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0486"(UniProt) intact:EBI-25618539|imex:IM-28178-45 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001170946.1|refseq:NP_689794.1|go:"GO:0090023"(positive regulation of neutrophil chemotaxis)|go:"GO:0090026"(positive regulation of monocyte chemotaxis)|go:"GO:0140284"(endoplasmic reticulum-endosome membrane contact site)|interpro:IPR000535(Major sperm protein)|interpro:IPR001251(Cellular retinaldehyde-binding/triple function, C-terminal)|interpro:IPR008962(PapD-like)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR036273|interpro:IPR036865|mint:Q8NHP6|rcsb pdb:6TQS|rcsb pdb:6TQT|rcsb pdb:6TQU|reactome:R-HSA-6798695|reactome:R-HSA-9013405|ensembl:ENSG00000130150(gene)|ensembl:ENST00000380492(transcript)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006935"(chemotaxis)|go:"GO:0016020"(membrane)|go:"GO:0035579"(specific granule membrane)|go:"GO:0044232"(organelle membrane contact site) refseq:NP_001159409.1|refseq:NP_001159410.1|refseq:NP_006795.3|refseq:XP_016879530.1|ensembl:ENSG00000131748(gene)|ensembl:ENST00000336308(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005768"(endosome)|go:"GO:0005829"(cytosol)|go:"GO:0006629"(lipid metabolic process)|go:"GO:0006701"(progesterone biosynthetic process)|go:"GO:0006839"(mitochondrial transport)|go:"GO:0008202"(steroid metabolic process)|go:"GO:0008203"(cholesterol metabolic process)|go:"GO:0015485"(cholesterol binding)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030301"(cholesterol transport)|go:"GO:0031902"(late endosome membrane)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0044232"(organelle membrane contact site)|go:"GO:0099044"(vesicle tethering to endoplasmic reticulum)|go:"GO:0120020"(cholesterol transfer activity)|go:"GO:0140284"(endoplasmic reticulum-endosome membrane contact site)|interpro:IPR000799(Steroidogenic acute regulatory protein)|interpro:IPR002913(Lipid-binding START)|interpro:IPR019498|interpro:IPR023393|interpro:IPR029867|rcsb pdb:1EM2|rcsb pdb:2I92|rcsb pdb:5I9J|rcsb pdb:6TQR|rcsb pdb:6TQU|reactome:R-HSA-196108 - - - figure legend:EV. 2B|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2020/05/21 2020/05/21 rogid:WEdwMYKpu1uQll5NXnMm4P51R4E9606 rogid:WukBgAECun0AKrfWzBlepgVuZlE9606 rigid:fxnjpASU8QRkHkoYVYWTa804T1U false his tag:c-c|sufficient binding region:282-490 flag tag:?-?|mutation disrupting interaction strength:207-208 - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:Q8NHP6 uniprotkb:Q9BXW6 intact:EBI-2812848|uniprotkb:Q8NA83|uniprotkb:Q8N3H2|ensembl:ENSP00000369860 intact:EBI-765918|uniprotkb:Q9BZF5|uniprotkb:Q9NW87|uniprotkb:B7Z7D3|ensembl:ENSP00000320291 psi-mi:mspd2_human(display_long)|uniprotkb:MOSPD2(gene name)|psi-mi:MOSPD2(display_short) psi-mi:osbl1_human(display_long)|uniprotkb:OSBPL1A(gene name)|psi-mi:OSBPL1A(display_short)|uniprotkb:ORP1(gene name synonym)|uniprotkb:OSBP8(gene name synonym)|uniprotkb:OSBPL1(gene name synonym)|uniprotkb:OSBPL1B(gene name synonym) psi-mi:"MI:0096"(pull down) Di et al. (2018) pubmed:29858488|imex:IM-28178 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0486"(UniProt) intact:EBI-25616983|imex:IM-28178-1 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001170946.1|refseq:NP_689794.1|go:"GO:0090023"(positive regulation of neutrophil chemotaxis)|go:"GO:0090026"(positive regulation of monocyte chemotaxis)|go:"GO:0140284"(endoplasmic reticulum-endosome membrane contact site)|interpro:IPR000535(Major sperm protein)|interpro:IPR001251(Cellular retinaldehyde-binding/triple function, C-terminal)|interpro:IPR008962(PapD-like)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR036273|interpro:IPR036865|mint:Q8NHP6|rcsb pdb:6TQS|rcsb pdb:6TQT|rcsb pdb:6TQU|reactome:R-HSA-6798695|reactome:R-HSA-9013405|ensembl:ENSG00000130150(gene)|ensembl:ENST00000380492(transcript)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006935"(chemotaxis)|go:"GO:0016020"(membrane)|go:"GO:0035579"(specific granule membrane)|go:"GO:0044232"(organelle membrane contact site) refseq:NP_001229437.1|refseq:NP_060500.3|refseq:NP_542164.2|refseq:XP_016881022.1|ensembl:ENSG00000141447(gene)|ensembl:ENST00000319481(transcript)|go:"GO:0005543"(phospholipid binding)|go:"GO:0005768"(endosome)|go:"GO:0005770"(late endosome)|go:"GO:0005829"(cytosol)|go:"GO:0006699"(bile acid biosynthetic process)|go:"GO:0008203"(cholesterol metabolic process)|go:"GO:0015248"(sterol transporter activity)|go:"GO:0015485"(cholesterol binding)|go:"GO:0016020"(membrane)|go:"GO:0016192"(vesicle-mediated transport)|go:"GO:0032934"(sterol binding)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0044232"(organelle membrane contact site)|go:"GO:0070062"(extracellular exosome)|interpro:IPR000648(Oxysterol-binding protein)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR002110(Ankyrin)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR018494|interpro:IPR020683|interpro:IPR036770|interpro:IPR037239|mint:Q9BXW6|rcsb pdb:5ZM5|rcsb pdb:5ZM6|rcsb pdb:5ZM7|rcsb pdb:6IYB|rcsb pdb:6TQS|reactome:R-HSA-192105|reactome:R-HSA-2132295|refseq:XP_016881023.1 - - - figure legend:Fig.2F|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2020/05/21 2020/05/21 rogid:WEdwMYKpu1uQll5NXnMm4P51R4E9606 rogid:IaZi6kaj9t0aU94PF/XOaxH1dNA9606 rigid:PViNSVICK/WUweVdABQL4nO3CmY false his tag:c-c|sufficient binding region:282-490(IPR000535)|mutation disrupting interaction strength:404-404,406-406 sufficient binding region:469-485|biotin tag:n-n - - psi-mi:"MI:0818"(molecular weight estimation by coomasie staining) psi-mi:"MI:0818"(molecular weight estimation by coomasie staining) uniprotkb:Q9P0L0 uniprotkb:Q9BXW6 intact:EBI-1059156|uniprotkb:Q9UBZ2|uniprotkb:O75453|uniprotkb:Q5U0E7|intact:EBI-2556404|uniprotkb:A6NDZ0|intact:EBI-2512000|uniprotkb:D3DUI3|ensembl:ENSP00000382880 intact:EBI-765918|uniprotkb:Q9BZF5|uniprotkb:Q9NW87|uniprotkb:B7Z7D3|ensembl:ENSP00000320291 psi-mi:vapa_human(display_long)|uniprotkb:VAPA(gene name)|psi-mi:VAPA(display_short)|uniprotkb:VAP33(gene name synonym)|uniprotkb:33 kDa VAMP-associated protein(gene name synonym) psi-mi:osbl1_human(display_long)|uniprotkb:OSBPL1A(gene name)|psi-mi:OSBPL1A(display_short)|uniprotkb:ORP1(gene name synonym)|uniprotkb:OSBP8(gene name synonym)|uniprotkb:OSBPL1(gene name synonym)|uniprotkb:OSBPL1B(gene name synonym) psi-mi:"MI:0096"(pull down) Di et al. (2018) pubmed:29858488|imex:IM-28178 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0486"(UniProt) intact:EBI-25616999|imex:IM-28178-25 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_003565.4|refseq:NP_919415.2|dip:DIP-41135N|go:"GO:0031982"(vesicle)|go:"GO:0033149"(FFAT motif binding)|go:"GO:0035577"(azurophil granule membrane)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0044791"(obsolete positive regulation by host of viral release from host cell)|go:"GO:0044828"(negative regulation by host of viral genome replication)|go:"GO:0044829"(positive regulation by host of viral genome replication)|go:"GO:0045296"(cadherin binding)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0061025"(membrane fusion)|go:"GO:0070972"(protein localization to endoplasmic reticulum)|go:"GO:0090114"(COPII-coated vesicle budding)|interpro:IPR000535(Major sperm protein)|interpro:IPR008962(PapD-like)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR016763(Vesicle-associated membrane protein)|mint:Q9P0L0|rcsb pdb:2RR3|rcsb pdb:6TQR|reactome:R-HSA-1660661|reactome:R-HSA-6798695|reactome:R-HSA-9609523|ensembl:ENSG00000101558(gene)|ensembl:ENST00000400000(transcript)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0031175"(neuron projection development)|go:"GO:0031965"(nuclear membrane)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005923"(bicellular tight junction)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0008017"(microtubule binding)|go:"GO:0008219"(cell death)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0016021"(integral component of membrane) refseq:NP_001229437.1|refseq:NP_060500.3|refseq:NP_542164.2|refseq:XP_016881022.1|ensembl:ENSG00000141447(gene)|ensembl:ENST00000319481(transcript)|go:"GO:0005543"(phospholipid binding)|go:"GO:0005768"(endosome)|go:"GO:0005770"(late endosome)|go:"GO:0005829"(cytosol)|go:"GO:0006699"(bile acid biosynthetic process)|go:"GO:0008203"(cholesterol metabolic process)|go:"GO:0015248"(sterol transporter activity)|go:"GO:0015485"(cholesterol binding)|go:"GO:0016020"(membrane)|go:"GO:0016192"(vesicle-mediated transport)|go:"GO:0032934"(sterol binding)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0044232"(organelle membrane contact site)|go:"GO:0070062"(extracellular exosome)|interpro:IPR000648(Oxysterol-binding protein)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR002110(Ankyrin)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR018494|interpro:IPR020683|interpro:IPR036770|interpro:IPR037239|mint:Q9BXW6|rcsb pdb:5ZM5|rcsb pdb:5ZM6|rcsb pdb:5ZM7|rcsb pdb:6IYB|rcsb pdb:6TQS|reactome:R-HSA-192105|reactome:R-HSA-2132295|refseq:XP_016881023.1 - - - figure legend:Fig.2F|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2020/05/21 2020/05/21 rogid:h8NG5Ak0n6b/iq2yKYMsLsJKpos9606 rogid:IaZi6kaj9t0aU94PF/XOaxH1dNA9606 rigid:HpNYrQ0m+Nn36Tfb/zyh3K5khn8 false his tag:c-c|sufficient binding region:8-212(IPR000535)|mutation disrupting interaction strength:94-94,96-96 sufficient binding region:469-485|biotin tag:n-n - - psi-mi:"MI:0818"(molecular weight estimation by coomasie staining) psi-mi:"MI:0818"(molecular weight estimation by coomasie staining) uniprotkb:O95292 uniprotkb:Q9BXW6 intact:EBI-1188298|uniprotkb:O95293|uniprotkb:Q9P0H0|uniprotkb:A2A2F2|ensembl:ENSP00000417175 intact:EBI-765918|uniprotkb:Q9BZF5|uniprotkb:Q9NW87|uniprotkb:B7Z7D3|ensembl:ENSP00000320291 psi-mi:vapb_human(display_long)|uniprotkb:VAPB(gene name)|psi-mi:VAPB(display_short)|uniprotkb:UNQ484/PRO983(orf name) psi-mi:osbl1_human(display_long)|uniprotkb:OSBPL1A(gene name)|psi-mi:OSBPL1A(display_short)|uniprotkb:ORP1(gene name synonym)|uniprotkb:OSBP8(gene name synonym)|uniprotkb:OSBPL1(gene name synonym)|uniprotkb:OSBPL1B(gene name synonym) psi-mi:"MI:0096"(pull down) Di et al. (2018) pubmed:29858488|imex:IM-28178 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0486"(UniProt) intact:EBI-25617013|imex:IM-28178-3 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001182606.1|refseq:NP_004729.1|ensembl:ENSG00000124164(gene)|ensembl:ENST00000475243(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0006874"(cellular calcium ion homeostasis)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0007029"(endoplasmic reticulum organization)|go:"GO:0008017"(microtubule binding)|go:"GO:0016021"(integral component of membrane)|go:"GO:0019048"(modulation by virus of host process)|go:"GO:0019899"(enzyme binding)|go:"GO:0030968"(endoplasmic reticulum unfolded protein response)|go:"GO:0033149"(FFAT motif binding)|go:"GO:0036498"(IRE1-mediated unfolded protein response)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0044790"(suppression of viral release by host)|go:"GO:0044791"(obsolete positive regulation by host of viral release from host cell)|go:"GO:0044828"(negative regulation by host of viral genome replication)|go:"GO:0044829"(positive regulation by host of viral genome replication)|go:"GO:0044830"(modulation by host of viral RNA genome replication)|go:"GO:0045070"(positive regulation of viral genome replication)|go:"GO:0045296"(cadherin binding)|go:"GO:0046725"(negative regulation by virus of viral protein levels in host cell)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0048487"(beta-tubulin binding)|go:"GO:0061817"(endoplasmic reticulum-plasma membrane tethering)|go:"GO:0090114"(COPII-coated vesicle budding)|go:"GO:0090158"(endoplasmic reticulum membrane organization)|interpro:IPR000535(Major sperm protein)|interpro:IPR008962(PapD-like)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR016763(Vesicle-associated membrane protein)|mint:O95292|rcsb pdb:2MDK|rcsb pdb:3IKK|reactome:R-HSA-1660661|reactome:R-HSA-8980692|reactome:R-HSA-9013106|reactome:R-HSA-9013404|reactome:R-HSA-9013405|reactome:R-HSA-9013408|dip:DIP-39816N refseq:NP_001229437.1|refseq:NP_060500.3|refseq:NP_542164.2|refseq:XP_016881022.1|ensembl:ENSG00000141447(gene)|ensembl:ENST00000319481(transcript)|go:"GO:0005543"(phospholipid binding)|go:"GO:0005768"(endosome)|go:"GO:0005770"(late endosome)|go:"GO:0005829"(cytosol)|go:"GO:0006699"(bile acid biosynthetic process)|go:"GO:0008203"(cholesterol metabolic process)|go:"GO:0015248"(sterol transporter activity)|go:"GO:0015485"(cholesterol binding)|go:"GO:0016020"(membrane)|go:"GO:0016192"(vesicle-mediated transport)|go:"GO:0032934"(sterol binding)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0044232"(organelle membrane contact site)|go:"GO:0070062"(extracellular exosome)|interpro:IPR000648(Oxysterol-binding protein)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR002110(Ankyrin)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR018494|interpro:IPR020683|interpro:IPR036770|interpro:IPR037239|mint:Q9BXW6|rcsb pdb:5ZM5|rcsb pdb:5ZM6|rcsb pdb:5ZM7|rcsb pdb:6IYB|rcsb pdb:6TQS|reactome:R-HSA-192105|reactome:R-HSA-2132295|refseq:XP_016881023.1 - - - figure legend:Fig.2F|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2020/05/21 2020/05/21 rogid:+TuApjAmnGF1UZonXIsrPaIN4Ak9606 rogid:IaZi6kaj9t0aU94PF/XOaxH1dNA9606 rigid:Ooagl/FhgQKirSP0ytRSJiRONrg false his tag:c-c|sufficient binding region:1-210(IPR000535)|mutation disrupting interaction strength:87-87,89-89 sufficient binding region:469-485|biotin tag:n-n - - psi-mi:"MI:0818"(molecular weight estimation by coomasie staining) psi-mi:"MI:0818"(molecular weight estimation by coomasie staining) uniprotkb:Q9P0L0 uniprotkb:Q9BXW6 intact:EBI-1059156|uniprotkb:Q9UBZ2|uniprotkb:O75453|uniprotkb:Q5U0E7|intact:EBI-2556404|uniprotkb:A6NDZ0|intact:EBI-2512000|uniprotkb:D3DUI3|ensembl:ENSP00000382880 intact:EBI-765918|uniprotkb:Q9BZF5|uniprotkb:Q9NW87|uniprotkb:B7Z7D3|ensembl:ENSP00000320291 psi-mi:vapa_human(display_long)|uniprotkb:VAPA(gene name)|psi-mi:VAPA(display_short)|uniprotkb:VAP33(gene name synonym)|uniprotkb:33 kDa VAMP-associated protein(gene name synonym) psi-mi:osbl1_human(display_long)|uniprotkb:OSBPL1A(gene name)|psi-mi:OSBPL1A(display_short)|uniprotkb:ORP1(gene name synonym)|uniprotkb:OSBP8(gene name synonym)|uniprotkb:OSBPL1(gene name synonym)|uniprotkb:OSBPL1B(gene name synonym) psi-mi:"MI:0107"(surface plasmon resonance) Di et al. (2018) pubmed:29858488|imex:IM-28178 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0486"(UniProt) intact:EBI-25617037|imex:IM-28178-5 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_003565.4|refseq:NP_919415.2|dip:DIP-41135N|go:"GO:0031982"(vesicle)|go:"GO:0033149"(FFAT motif binding)|go:"GO:0035577"(azurophil granule membrane)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0044791"(obsolete positive regulation by host of viral release from host cell)|go:"GO:0044828"(negative regulation by host of viral genome replication)|go:"GO:0044829"(positive regulation by host of viral genome replication)|go:"GO:0045296"(cadherin binding)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0061025"(membrane fusion)|go:"GO:0070972"(protein localization to endoplasmic reticulum)|go:"GO:0090114"(COPII-coated vesicle budding)|interpro:IPR000535(Major sperm protein)|interpro:IPR008962(PapD-like)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR016763(Vesicle-associated membrane protein)|mint:Q9P0L0|rcsb pdb:2RR3|rcsb pdb:6TQR|reactome:R-HSA-1660661|reactome:R-HSA-6798695|reactome:R-HSA-9609523|ensembl:ENSG00000101558(gene)|ensembl:ENST00000400000(transcript)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0031175"(neuron projection development)|go:"GO:0031965"(nuclear membrane)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005923"(bicellular tight junction)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0008017"(microtubule binding)|go:"GO:0008219"(cell death)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0016021"(integral component of membrane) refseq:NP_001229437.1|refseq:NP_060500.3|refseq:NP_542164.2|refseq:XP_016881022.1|ensembl:ENSG00000141447(gene)|ensembl:ENST00000319481(transcript)|go:"GO:0005543"(phospholipid binding)|go:"GO:0005768"(endosome)|go:"GO:0005770"(late endosome)|go:"GO:0005829"(cytosol)|go:"GO:0006699"(bile acid biosynthetic process)|go:"GO:0008203"(cholesterol metabolic process)|go:"GO:0015248"(sterol transporter activity)|go:"GO:0015485"(cholesterol binding)|go:"GO:0016020"(membrane)|go:"GO:0016192"(vesicle-mediated transport)|go:"GO:0032934"(sterol binding)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0044232"(organelle membrane contact site)|go:"GO:0070062"(extracellular exosome)|interpro:IPR000648(Oxysterol-binding protein)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR002110(Ankyrin)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR018494|interpro:IPR020683|interpro:IPR036770|interpro:IPR037239|mint:Q9BXW6|rcsb pdb:5ZM5|rcsb pdb:5ZM6|rcsb pdb:5ZM7|rcsb pdb:6IYB|rcsb pdb:6TQS|reactome:R-HSA-192105|reactome:R-HSA-2132295|refseq:XP_016881023.1 - - - figure legend:Fig.3B, 3E|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) kd:6.0x10^-7(molar) 2020/05/21 2020/05/21 rogid:h8NG5Ak0n6b/iq2yKYMsLsJKpos9606 rogid:IaZi6kaj9t0aU94PF/XOaxH1dNA9606 rigid:HpNYrQ0m+Nn36Tfb/zyh3K5khn8 false his tag:c-c|sufficient binding region:8-212(IPR000535) sufficient binding region:469-485|biotin tag:n-n - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q8NHP6 uniprotkb:Q9BXW6 intact:EBI-2812848|uniprotkb:Q8NA83|uniprotkb:Q8N3H2|ensembl:ENSP00000369860 intact:EBI-765918|uniprotkb:Q9BZF5|uniprotkb:Q9NW87|uniprotkb:B7Z7D3|ensembl:ENSP00000320291 psi-mi:mspd2_human(display_long)|uniprotkb:MOSPD2(gene name)|psi-mi:MOSPD2(display_short) psi-mi:osbl1_human(display_long)|uniprotkb:OSBPL1A(gene name)|psi-mi:OSBPL1A(display_short)|uniprotkb:ORP1(gene name synonym)|uniprotkb:OSBP8(gene name synonym)|uniprotkb:OSBPL1(gene name synonym)|uniprotkb:OSBPL1B(gene name synonym) psi-mi:"MI:0107"(surface plasmon resonance) Di et al. (2018) pubmed:29858488|imex:IM-28178 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0486"(UniProt) intact:EBI-25617051|imex:IM-28178-27 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001170946.1|refseq:NP_689794.1|go:"GO:0090023"(positive regulation of neutrophil chemotaxis)|go:"GO:0090026"(positive regulation of monocyte chemotaxis)|go:"GO:0140284"(endoplasmic reticulum-endosome membrane contact site)|interpro:IPR000535(Major sperm protein)|interpro:IPR001251(Cellular retinaldehyde-binding/triple function, C-terminal)|interpro:IPR008962(PapD-like)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR036273|interpro:IPR036865|mint:Q8NHP6|rcsb pdb:6TQS|rcsb pdb:6TQT|rcsb pdb:6TQU|reactome:R-HSA-6798695|reactome:R-HSA-9013405|ensembl:ENSG00000130150(gene)|ensembl:ENST00000380492(transcript)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006935"(chemotaxis)|go:"GO:0016020"(membrane)|go:"GO:0035579"(specific granule membrane)|go:"GO:0044232"(organelle membrane contact site) refseq:NP_001229437.1|refseq:NP_060500.3|refseq:NP_542164.2|refseq:XP_016881022.1|ensembl:ENSG00000141447(gene)|ensembl:ENST00000319481(transcript)|go:"GO:0005543"(phospholipid binding)|go:"GO:0005768"(endosome)|go:"GO:0005770"(late endosome)|go:"GO:0005829"(cytosol)|go:"GO:0006699"(bile acid biosynthetic process)|go:"GO:0008203"(cholesterol metabolic process)|go:"GO:0015248"(sterol transporter activity)|go:"GO:0015485"(cholesterol binding)|go:"GO:0016020"(membrane)|go:"GO:0016192"(vesicle-mediated transport)|go:"GO:0032934"(sterol binding)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0044232"(organelle membrane contact site)|go:"GO:0070062"(extracellular exosome)|interpro:IPR000648(Oxysterol-binding protein)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR002110(Ankyrin)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR018494|interpro:IPR020683|interpro:IPR036770|interpro:IPR037239|mint:Q9BXW6|rcsb pdb:5ZM5|rcsb pdb:5ZM6|rcsb pdb:5ZM7|rcsb pdb:6IYB|rcsb pdb:6TQS|reactome:R-HSA-192105|reactome:R-HSA-2132295|refseq:XP_016881023.1 - - - figure legend:Fig.3A,D,G|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) kd:9.0x10^-7(molar) 2020/05/21 2020/05/21 rogid:WEdwMYKpu1uQll5NXnMm4P51R4E9606 rogid:IaZi6kaj9t0aU94PF/XOaxH1dNA9606 rigid:PViNSVICK/WUweVdABQL4nO3CmY false his tag:c-c|sufficient binding region:282-490(IPR000535)|mutation disrupting interaction strength:404-404,406-406 sufficient binding region:469-485|biotin tag:n-n - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:O95292 uniprotkb:Q9BXW6 intact:EBI-1188298|uniprotkb:O95293|uniprotkb:Q9P0H0|uniprotkb:A2A2F2|ensembl:ENSP00000417175 intact:EBI-765918|uniprotkb:Q9BZF5|uniprotkb:Q9NW87|uniprotkb:B7Z7D3|ensembl:ENSP00000320291 psi-mi:vapb_human(display_long)|uniprotkb:VAPB(gene name)|psi-mi:VAPB(display_short)|uniprotkb:UNQ484/PRO983(orf name) psi-mi:osbl1_human(display_long)|uniprotkb:OSBPL1A(gene name)|psi-mi:OSBPL1A(display_short)|uniprotkb:ORP1(gene name synonym)|uniprotkb:OSBP8(gene name synonym)|uniprotkb:OSBPL1(gene name synonym)|uniprotkb:OSBPL1B(gene name synonym) psi-mi:"MI:0107"(surface plasmon resonance) Di et al. (2018) pubmed:29858488|imex:IM-28178 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0486"(UniProt) intact:EBI-25617065|imex:IM-28178-7 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001182606.1|refseq:NP_004729.1|ensembl:ENSG00000124164(gene)|ensembl:ENST00000475243(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0006874"(cellular calcium ion homeostasis)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0007029"(endoplasmic reticulum organization)|go:"GO:0008017"(microtubule binding)|go:"GO:0016021"(integral component of membrane)|go:"GO:0019048"(modulation by virus of host process)|go:"GO:0019899"(enzyme binding)|go:"GO:0030968"(endoplasmic reticulum unfolded protein response)|go:"GO:0033149"(FFAT motif binding)|go:"GO:0036498"(IRE1-mediated unfolded protein response)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0044790"(suppression of viral release by host)|go:"GO:0044791"(obsolete positive regulation by host of viral release from host cell)|go:"GO:0044828"(negative regulation by host of viral genome replication)|go:"GO:0044829"(positive regulation by host of viral genome replication)|go:"GO:0044830"(modulation by host of viral RNA genome replication)|go:"GO:0045070"(positive regulation of viral genome replication)|go:"GO:0045296"(cadherin binding)|go:"GO:0046725"(negative regulation by virus of viral protein levels in host cell)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0048487"(beta-tubulin binding)|go:"GO:0061817"(endoplasmic reticulum-plasma membrane tethering)|go:"GO:0090114"(COPII-coated vesicle budding)|go:"GO:0090158"(endoplasmic reticulum membrane organization)|interpro:IPR000535(Major sperm protein)|interpro:IPR008962(PapD-like)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR016763(Vesicle-associated membrane protein)|mint:O95292|rcsb pdb:2MDK|rcsb pdb:3IKK|reactome:R-HSA-1660661|reactome:R-HSA-8980692|reactome:R-HSA-9013106|reactome:R-HSA-9013404|reactome:R-HSA-9013405|reactome:R-HSA-9013408|dip:DIP-39816N refseq:NP_001229437.1|refseq:NP_060500.3|refseq:NP_542164.2|refseq:XP_016881022.1|ensembl:ENSG00000141447(gene)|ensembl:ENST00000319481(transcript)|go:"GO:0005543"(phospholipid binding)|go:"GO:0005768"(endosome)|go:"GO:0005770"(late endosome)|go:"GO:0005829"(cytosol)|go:"GO:0006699"(bile acid biosynthetic process)|go:"GO:0008203"(cholesterol metabolic process)|go:"GO:0015248"(sterol transporter activity)|go:"GO:0015485"(cholesterol binding)|go:"GO:0016020"(membrane)|go:"GO:0016192"(vesicle-mediated transport)|go:"GO:0032934"(sterol binding)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0044232"(organelle membrane contact site)|go:"GO:0070062"(extracellular exosome)|interpro:IPR000648(Oxysterol-binding protein)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR002110(Ankyrin)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR018494|interpro:IPR020683|interpro:IPR036770|interpro:IPR037239|mint:Q9BXW6|rcsb pdb:5ZM5|rcsb pdb:5ZM6|rcsb pdb:5ZM7|rcsb pdb:6IYB|rcsb pdb:6TQS|reactome:R-HSA-192105|reactome:R-HSA-2132295|refseq:XP_016881023.1 - - - figure legend:Fig. 3C, 3F|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) kd:7.0x10^-7(molar) 2020/05/21 2020/05/21 rogid:+TuApjAmnGF1UZonXIsrPaIN4Ak9606 rogid:IaZi6kaj9t0aU94PF/XOaxH1dNA9606 rigid:Ooagl/FhgQKirSP0ytRSJiRONrg false his tag:c-c|sufficient binding region:1-210(IPR000535) sufficient binding region:469-485|biotin tag:n-n - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q8NHP6 uniprotkb:P22059 intact:EBI-2812848|uniprotkb:Q8NA83|uniprotkb:Q8N3H2|ensembl:ENSP00000369860 intact:EBI-2681902|uniprotkb:Q6P524|ensembl:ENSP00000263847 psi-mi:mspd2_human(display_long)|uniprotkb:MOSPD2(gene name)|psi-mi:MOSPD2(display_short) psi-mi:osbp1_human(display_long)|uniprotkb:OSBP1(gene name synonym)|uniprotkb:OSBP(gene name)|psi-mi:OSBP(display_short) psi-mi:"MI:0038"(dynamic light scattering) Di et al. (2018) pubmed:29858488|imex:IM-28178 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0486"(UniProt) intact:EBI-25617363|imex:IM-28178-9 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001170946.1|refseq:NP_689794.1|go:"GO:0090023"(positive regulation of neutrophil chemotaxis)|go:"GO:0090026"(positive regulation of monocyte chemotaxis)|go:"GO:0140284"(endoplasmic reticulum-endosome membrane contact site)|interpro:IPR000535(Major sperm protein)|interpro:IPR001251(Cellular retinaldehyde-binding/triple function, C-terminal)|interpro:IPR008962(PapD-like)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR036273|interpro:IPR036865|mint:Q8NHP6|rcsb pdb:6TQS|rcsb pdb:6TQT|rcsb pdb:6TQU|reactome:R-HSA-6798695|reactome:R-HSA-9013405|ensembl:ENSG00000130150(gene)|ensembl:ENST00000380492(transcript)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006935"(chemotaxis)|go:"GO:0016020"(membrane)|go:"GO:0035579"(specific granule membrane)|go:"GO:0044232"(organelle membrane contact site) refseq:NP_002547.1|ensembl:ENSG00000110048(gene)|ensembl:ENST00000263847(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006699"(bile acid biosynthetic process)|go:"GO:0008142"(oxysterol binding)|go:"GO:0015248"(sterol transporter activity)|go:"GO:0015918"(sterol transport)|go:"GO:0016020"(membrane)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030054"(cell junction)|go:"GO:0032367"(intracellular cholesterol transport)|go:"GO:0032934"(sterol binding)|go:"GO:0035774"(positive regulation of insulin secretion involved in cellular response to glucose stimulus)|go:"GO:0042531"(positive regulation of tyrosine phosphorylation of STAT protein)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0070273"(phosphatidylinositol-4-phosphate binding)|go:"GO:0097038"(perinuclear endoplasmic reticulum)|go:"GO:0120015"(sterol transfer activity)|go:"GO:1904411"(positive regulation of secretory granule organization)|interpro:IPR000648(Oxysterol-binding protein)|interpro:IPR018494|interpro:IPR037239|rcsb pdb:2RR3|reactome:R-HSA-1660661|reactome:R-HSA-192105|interpro:IPR001849(Pleckstrin-like)|interpro:IPR011993(Pleckstrin homology-type) - - - figure legend:Fig.4E|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2020/05/21 2020/05/21 rogid:WEdwMYKpu1uQll5NXnMm4P51R4E9606 rogid:9LgzhfWQ0E/ECTTKA1OogQSyuAI9606 rigid:yU0BCCLESbChuDU5CreJkou0uYE false his tag:c-c|sufficient binding region:282-490(IPR000535)|mutation disrupting interaction strength:404-404,406-406 sufficient binding region:344-374|biotin tag:n-n - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:Q8NHP6 uniprotkb:P15927 intact:EBI-2812848|uniprotkb:Q8NA83|uniprotkb:Q8N3H2|ensembl:ENSP00000369860 intact:EBI-621404|ensembl:ENSP00000363021|uniprotkb:Q52II0|uniprotkb:Q5TEI9|uniprotkb:Q5TEJ5 psi-mi:mspd2_human(display_long)|uniprotkb:MOSPD2(gene name)|psi-mi:MOSPD2(display_short) psi-mi:rfa2_human(display_long)|uniprotkb:RPA34(gene name synonym)|uniprotkb:Replication protein A 34 kDa subunit(gene name synonym)|uniprotkb:Replication factor A protein 2(gene name synonym)|uniprotkb:RPA2(gene name)|psi-mi:RPA2(display_short)|uniprotkb:REPA2(gene name synonym)|uniprotkb:RPA32(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Di et al. (2018) pubmed:29858488|imex:IM-28178 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-25617558|imex:IM-28178-11 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001170946.1|refseq:NP_689794.1|go:"GO:0090023"(positive regulation of neutrophil chemotaxis)|go:"GO:0090026"(positive regulation of monocyte chemotaxis)|go:"GO:0140284"(endoplasmic reticulum-endosome membrane contact site)|interpro:IPR000535(Major sperm protein)|interpro:IPR001251(Cellular retinaldehyde-binding/triple function, C-terminal)|interpro:IPR008962(PapD-like)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR036273|interpro:IPR036865|mint:Q8NHP6|rcsb pdb:6TQS|rcsb pdb:6TQT|rcsb pdb:6TQU|reactome:R-HSA-6798695|reactome:R-HSA-9013405|ensembl:ENSG00000130150(gene)|ensembl:ENST00000380492(transcript)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006935"(chemotaxis)|go:"GO:0016020"(membrane)|go:"GO:0035579"(specific granule membrane)|go:"GO:0044232"(organelle membrane contact site) rcsb pdb:1L1O|rcsb pdb:1QUQ|rcsb pdb:1Z1D|rcsb pdb:2PI2|rcsb pdb:2PQA|rcsb pdb:2Z6K|rcsb pdb:3KDF|rcsb pdb:4MQV|rcsb pdb:4OU0|reactome:R-HSA-110312|reactome:R-HSA-110314|reactome:R-HSA-110320|reactome:R-HSA-174437|reactome:R-HSA-176187|reactome:R-HSA-3371453|reactome:R-HSA-3371511|reactome:R-HSA-5358565|reactome:R-HSA-5358606|reactome:R-HSA-5651801|reactome:R-HSA-5655862|reactome:R-HSA-5656121|reactome:R-HSA-5656169|reactome:R-HSA-5685938|reactome:R-HSA-5685942|reactome:R-HSA-5693607|reactome:R-HSA-5693616|reactome:R-HSA-5696395|reactome:R-HSA-5696397|reactome:R-HSA-5696400|reactome:R-HSA-6782135|reactome:R-HSA-6782210|reactome:R-HSA-6783310|reactome:R-HSA-6804756|reactome:R-HSA-68962|reactome:R-HSA-69166|reactome:R-HSA-69473|reactome:R-HSA-912446|rcsb pdb:1DPU|ensembl:ENSG00000117748(gene)|ensembl:ENST00000373912(transcript)|go:"GO:0000723"(telomere maintenance)|go:"GO:0000724"(double-strand break repair via homologous recombination)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0000785"(chromatin)|go:"GO:0003684"(damaged DNA binding)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005662"(DNA replication factor A complex)|go:"GO:0006260"(DNA replication)|go:"GO:0006284"(base-excision repair)|go:"GO:0006289"(nucleotide-excision repair)|go:"GO:0006298"(mismatch repair)|go:"GO:0010569"(regulation of double-strand break repair via homologous recombination)|go:"GO:0016604"(nuclear body)|go:"GO:0016605"(PML body)|go:"GO:0019899"(enzyme binding)|go:"GO:0019903"(protein phosphatase binding)|go:"GO:0031571"(mitotic G1 DNA damage checkpoint signaling)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0034502"(protein localization to chromosome)|go:"GO:0047485"(protein N-terminus binding)|go:"GO:0098505"(G-rich strand telomeric DNA binding)|go:"GO:2000001"(regulation of DNA damage checkpoint)|interpro:IPR012340(Nucleic acid-binding, OB-fold)|interpro:IPR014646(Replication protein A, subunit RPA32)|interpro:IPR014892(Replication protein A C terminal)|interpro:IPR036388|interpro:IPR036390|interpro:IPR040260|mint:P15927|refseq:NP_001273005.1|refseq:NP_002937.1|refseq:NP_001284487.1|dip:DIP-24187N - - - figure legend:Fig. 5A, Supp. Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells) - 2020/05/21 2021/04/12 rogid:WEdwMYKpu1uQll5NXnMm4P51R4E9606 rogid:+Ute8Lq5hnN0sLAQNWZb0cAbcTI9606 rigid:1P63pNv1yn3F27gcT2OsGH/3EDQ false green fluorescent protein tag:n-n|mutation disrupting interaction strength:406-406,404-404 - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q8NHP6 uniprotkb:P35244 intact:EBI-2812848|uniprotkb:Q8NA83|uniprotkb:Q8N3H2|ensembl:ENSP00000369860 intact:EBI-621428|ensembl:ENSP00000223129|ensembl:ENSP00000379914|uniprotkb:Q549U6|intact:EBI-1058317 psi-mi:mspd2_human(display_long)|uniprotkb:MOSPD2(gene name)|psi-mi:MOSPD2(display_short) psi-mi:rfa3_human(display_long)|uniprotkb:Replication factor A protein 3(gene name synonym)|uniprotkb:RPA3(gene name)|psi-mi:RPA3(display_short)|uniprotkb:REPA3(gene name synonym)|uniprotkb:RPA14(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Di et al. (2018) pubmed:29858488|imex:IM-28178 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-25617558|imex:IM-28178-11 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001170946.1|refseq:NP_689794.1|go:"GO:0090023"(positive regulation of neutrophil chemotaxis)|go:"GO:0090026"(positive regulation of monocyte chemotaxis)|go:"GO:0140284"(endoplasmic reticulum-endosome membrane contact site)|interpro:IPR000535(Major sperm protein)|interpro:IPR001251(Cellular retinaldehyde-binding/triple function, C-terminal)|interpro:IPR008962(PapD-like)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR036273|interpro:IPR036865|mint:Q8NHP6|rcsb pdb:6TQS|rcsb pdb:6TQT|rcsb pdb:6TQU|reactome:R-HSA-6798695|reactome:R-HSA-9013405|ensembl:ENSG00000130150(gene)|ensembl:ENST00000380492(transcript)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006935"(chemotaxis)|go:"GO:0016020"(membrane)|go:"GO:0035579"(specific granule membrane)|go:"GO:0044232"(organelle membrane contact site) go:"GO:0007346"(regulation of mitotic cell cycle)|go:"GO:0035861"(site of double-strand break)|ensembl:ENSG00000106399(gene)|go:"GO:0042127"(regulation of cell population proliferation)|interpro:IPR012340(Nucleic acid-binding, OB-fold)|interpro:IPR013970(Replication factor A protein 3)|mint:P35244|rcsb pdb:1L1O|rcsb pdb:1QUQ|rcsb pdb:2PI2|rcsb pdb:2PQA|rcsb pdb:2Z6K|rcsb pdb:3KDF|reactome:R-HSA-110312|reactome:R-HSA-110314|reactome:R-HSA-110320|reactome:R-HSA-174437|reactome:R-HSA-176187|reactome:R-HSA-3371453|ensembl:ENST00000223129(transcript)|reactome:R-HSA-3371511|reactome:R-HSA-5358565|reactome:R-HSA-5358606|reactome:R-HSA-5651801|reactome:R-HSA-5655862|reactome:R-HSA-5656121|ensembl:ENST00000396682(transcript)|reactome:R-HSA-5656169|reactome:R-HSA-5685938|reactome:R-HSA-5685942|reactome:R-HSA-5693607|reactome:R-HSA-5693616|reactome:R-HSA-5696395|reactome:R-HSA-5696397|reactome:R-HSA-5696400|reactome:R-HSA-6782135|reactome:R-HSA-6782210|reactome:R-HSA-6783310|reactome:R-HSA-6804756|reactome:R-HSA-68962|reactome:R-HSA-69166|reactome:R-HSA-69473|reactome:R-HSA-912446|go:"GO:0000723"(telomere maintenance)|go:"GO:0000724"(double-strand break repair via homologous recombination)|go:"GO:0003684"(damaged DNA binding)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005662"(DNA replication factor A complex)|go:"GO:0006260"(DNA replication)|go:"GO:0006284"(base-excision repair)|go:"GO:0006289"(nucleotide-excision repair)|go:"GO:0006298"(mismatch repair)|refseq:NP_002938.1|dip:DIP-24190N - - - figure legend:Fig. 5A, Supp. Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells) - 2020/05/21 2021/04/12 rogid:WEdwMYKpu1uQll5NXnMm4P51R4E9606 rogid:hHO7MxGGHUjz30HXSBZd9cXOq6I9606 rigid:1P63pNv1yn3F27gcT2OsGH/3EDQ false green fluorescent protein tag:n-n|mutation disrupting interaction strength:406-406,404-404 - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q8NHP6 uniprotkb:P27694 intact:EBI-2812848|uniprotkb:Q8NA83|uniprotkb:Q8N3H2|ensembl:ENSP00000369860 intact:EBI-621389|ensembl:ENSP00000254719|uniprotkb:Q59ES9|uniprotkb:A8K0Y9 psi-mi:mspd2_human(display_long)|uniprotkb:MOSPD2(gene name)|psi-mi:MOSPD2(display_short) psi-mi:rfa1_human(display_long)|uniprotkb:Replication factor A protein 1(gene name synonym)|uniprotkb:Single-stranded DNA-binding protein(gene name synonym)|uniprotkb:RPA1(gene name)|psi-mi:RPA1(display_short)|uniprotkb:REPA1(gene name synonym)|uniprotkb:RPA70(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Di et al. (2018) pubmed:29858488|imex:IM-28178 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-25617558|imex:IM-28178-11 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001170946.1|refseq:NP_689794.1|go:"GO:0090023"(positive regulation of neutrophil chemotaxis)|go:"GO:0090026"(positive regulation of monocyte chemotaxis)|go:"GO:0140284"(endoplasmic reticulum-endosome membrane contact site)|interpro:IPR000535(Major sperm protein)|interpro:IPR001251(Cellular retinaldehyde-binding/triple function, C-terminal)|interpro:IPR008962(PapD-like)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR036273|interpro:IPR036865|mint:Q8NHP6|rcsb pdb:6TQS|rcsb pdb:6TQT|rcsb pdb:6TQU|reactome:R-HSA-6798695|reactome:R-HSA-9013405|ensembl:ENSG00000130150(gene)|ensembl:ENST00000380492(transcript)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006935"(chemotaxis)|go:"GO:0016020"(membrane)|go:"GO:0035579"(specific granule membrane)|go:"GO:0044232"(organelle membrane contact site) ensembl:ENSG00000132383(gene)|ensembl:ENST00000254719(transcript)|go:"GO:0000723"(telomere maintenance)|go:"GO:0000724"(double-strand break repair via homologous recombination)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0003684"(damaged DNA binding)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005662"(DNA replication factor A complex)|go:"GO:0006260"(DNA replication)|go:"GO:0006261"(DNA-dependent DNA replication)|go:"GO:0006281"(DNA repair)|go:"GO:0006284"(base-excision repair)|go:"GO:0006289"(nucleotide-excision repair)|go:"GO:0006298"(mismatch repair)|go:"GO:0006310"(DNA recombination)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0007004"(telomere maintenance via telomerase)|go:"GO:0016605"(PML body)|go:"GO:0034502"(protein localization to chromosome)|go:"GO:0043047"(single-stranded telomeric DNA binding)|go:"GO:0046872"(metal ion binding)|go:"GO:0051321"(meiotic cell cycle)|go:"GO:0090734"(site of DNA damage)|go:"GO:0098505"(G-rich strand telomeric DNA binding)|interpro:IPR004365(Nucleic acid binding, OB-fold, tRNA/helicase-type)|interpro:IPR004591(Replication factor-a protein 1 Rpa1)|interpro:IPR007199(Replication factor-A protein 1, N-terminal)|interpro:IPR012340(Nucleic acid-binding, OB-fold)|interpro:IPR013955(Replication factor-A, C-terminal)|interpro:IPR031657|go:"GO:0006268"(DNA unwinding involved in DNA replication)|mint:P27694|rcsb pdb:1EWI|rcsb pdb:1FGU|rcsb pdb:1JMC|rcsb pdb:1L1O|rcsb pdb:2B29|rcsb pdb:2B3G|rcsb pdb:4IJH|rcsb pdb:4IJL|rcsb pdb:4IPC|rcsb pdb:4IPD|rcsb pdb:4IPG|rcsb pdb:4IPH|rcsb pdb:4LUO|rcsb pdb:4LUV|rcsb pdb:4LUZ|rcsb pdb:4LW1|rcsb pdb:4LWC|rcsb pdb:4NB3|rcsb pdb:4O0A|rcsb pdb:4R4C|rcsb pdb:4R4I|rcsb pdb:4R4O|rcsb pdb:4R4Q|rcsb pdb:4R4T|rcsb pdb:5E7N|rcsb pdb:5EAY|rcsb pdb:5N85|rcsb pdb:5N8A|reactome:R-HSA-110312|reactome:R-HSA-110314|reactome:R-HSA-110320|reactome:R-HSA-174437|reactome:R-HSA-176187|reactome:R-HSA-3371453|reactome:R-HSA-3371511|reactome:R-HSA-5358565|reactome:R-HSA-5358606|reactome:R-HSA-5651801|reactome:R-HSA-5655862|reactome:R-HSA-5656121|reactome:R-HSA-5656169|reactome:R-HSA-5685938|reactome:R-HSA-5685942|reactome:R-HSA-5693607|reactome:R-HSA-5693616|reactome:R-HSA-5696395|reactome:R-HSA-5696397|reactome:R-HSA-5696400|reactome:R-HSA-6782135|reactome:R-HSA-6782210|reactome:R-HSA-6783310|reactome:R-HSA-6804756|reactome:R-HSA-68962|reactome:R-HSA-69166|reactome:R-HSA-69473|reactome:R-HSA-912446|reactome:R-HSA-3108214|refseq:NP_002936.1|dip:DIP-24189N - - - figure legend:Fig. 5A, Supp. Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells) - 2020/05/21 2021/04/12 rogid:WEdwMYKpu1uQll5NXnMm4P51R4E9606 rogid:DRZpMUlGyS0Qa5XFEtx71k0iPig9606 rigid:1P63pNv1yn3F27gcT2OsGH/3EDQ false green fluorescent protein tag:n-n|mutation disrupting interaction strength:406-406,404-404 - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q8NHP6 uniprotkb:Q5JR95 intact:EBI-2812848|uniprotkb:Q8NA83|uniprotkb:Q8N3H2|ensembl:ENSP00000369860 intact:EBI-7641926|ensembl:ENSP00000361283|intact:MINT-6488985 psi-mi:mspd2_human(display_long)|uniprotkb:MOSPD2(gene name)|psi-mi:MOSPD2(display_short) psi-mi:q5jr95_human(display_long)|uniprotkb:RPS8(gene name)|psi-mi:RPS8(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Di et al. (2018) pubmed:29858488|imex:IM-28178 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-25617558|imex:IM-28178-11 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001170946.1|refseq:NP_689794.1|go:"GO:0090023"(positive regulation of neutrophil chemotaxis)|go:"GO:0090026"(positive regulation of monocyte chemotaxis)|go:"GO:0140284"(endoplasmic reticulum-endosome membrane contact site)|interpro:IPR000535(Major sperm protein)|interpro:IPR001251(Cellular retinaldehyde-binding/triple function, C-terminal)|interpro:IPR008962(PapD-like)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR036273|interpro:IPR036865|mint:Q8NHP6|rcsb pdb:6TQS|rcsb pdb:6TQT|rcsb pdb:6TQU|reactome:R-HSA-6798695|reactome:R-HSA-9013405|ensembl:ENSG00000130150(gene)|ensembl:ENST00000380492(transcript)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006935"(chemotaxis)|go:"GO:0016020"(membrane)|go:"GO:0035579"(specific granule membrane)|go:"GO:0044232"(organelle membrane contact site) ensembl:ENSG00000142937(gene)|ensembl:ENST00000372209(transcript)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005829"(cytosol)|go:"GO:0005840"(ribosome)|go:"GO:0006412"(translation)|interpro:IPR001047(Ribosomal protein S8e)|interpro:IPR018283|interpro:IPR022309|interpro:IPR042563|mint:Q5JR95 - - comment:mint figure legend:Fig. 5A, Supp. Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells) - 2020/05/21 2021/04/12 rogid:WEdwMYKpu1uQll5NXnMm4P51R4E9606 rogid:FYlZuPYvEjyEHkY1/DrO40T8A3U9606 rigid:1P63pNv1yn3F27gcT2OsGH/3EDQ false green fluorescent protein tag:n-n|mutation disrupting interaction strength:406-406,404-404 - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q8NHP6 uniprotkb:Q9BSD7 intact:EBI-2812848|uniprotkb:Q8NA83|uniprotkb:Q8N3H2|ensembl:ENSP00000369860 intact:EBI-2689235|ensembl:ENSP00000355587 psi-mi:mspd2_human(display_long)|uniprotkb:MOSPD2(gene name)|psi-mi:MOSPD2(display_short) psi-mi:ntpcr_human(display_long)|uniprotkb:Nucleoside triphosphate phosphohydrolase(gene name synonym)|uniprotkb:NTPCR(gene name)|psi-mi:NTPCR(display_short)|uniprotkb:C1orf57(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Di et al. (2018) pubmed:29858488|imex:IM-28178 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-25617558|imex:IM-28178-11 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001170946.1|refseq:NP_689794.1|go:"GO:0090023"(positive regulation of neutrophil chemotaxis)|go:"GO:0090026"(positive regulation of monocyte chemotaxis)|go:"GO:0140284"(endoplasmic reticulum-endosome membrane contact site)|interpro:IPR000535(Major sperm protein)|interpro:IPR001251(Cellular retinaldehyde-binding/triple function, C-terminal)|interpro:IPR008962(PapD-like)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR036273|interpro:IPR036865|mint:Q8NHP6|rcsb pdb:6TQS|rcsb pdb:6TQT|rcsb pdb:6TQU|reactome:R-HSA-6798695|reactome:R-HSA-9013405|ensembl:ENSG00000130150(gene)|ensembl:ENST00000380492(transcript)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006935"(chemotaxis)|go:"GO:0016020"(membrane)|go:"GO:0035579"(specific granule membrane)|go:"GO:0044232"(organelle membrane contact site) refseq:NP_115700.1|interpro:IPR027417|mint:Q9BSD7|rcsb pdb:2I3B|ensembl:ENSG00000135778(gene)|ensembl:ENST00000366628(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0016020"(membrane)|go:"GO:0017111"(nucleoside-triphosphatase activity)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR004948(Protein of unknown function DUF265)|refseq:NP_001316382.1 - - - figure legend:Fig. 5A, Supp. Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells) - 2020/05/21 2021/04/12 rogid:WEdwMYKpu1uQll5NXnMm4P51R4E9606 rogid:tJoP+XQzoa4urq6g1rdZhMWO49g9606 rigid:1P63pNv1yn3F27gcT2OsGH/3EDQ false green fluorescent protein tag:n-n|mutation disrupting interaction strength:406-406,404-404 - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q8NHP6 uniprotkb:P40939 intact:EBI-2812848|uniprotkb:Q8NA83|uniprotkb:Q8N3H2|ensembl:ENSP00000369860 intact:EBI-356720|uniprotkb:Q16679|uniprotkb:Q96GT7|uniprotkb:B2R7L4|uniprotkb:B4DYP2|uniprotkb:Q9UQC5|ensembl:ENSP00000370023|uniprotkb:Q53T69|uniprotkb:Q53TA2 psi-mi:mspd2_human(display_long)|uniprotkb:MOSPD2(gene name)|psi-mi:MOSPD2(display_short) psi-mi:echa_human(display_long)|uniprotkb:HADHA(gene name)|psi-mi:HADHA(display_short)|uniprotkb:HADH(gene name synonym)|uniprotkb:TP-alpha(gene name synonym)|uniprotkb:78 kDa gastrin-binding protein(gene name synonym)|uniprotkb:Monolysocardiolipin acyltransferase(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Di et al. (2018) pubmed:29858488|imex:IM-28178 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-25617558|imex:IM-28178-11 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001170946.1|refseq:NP_689794.1|go:"GO:0090023"(positive regulation of neutrophil chemotaxis)|go:"GO:0090026"(positive regulation of monocyte chemotaxis)|go:"GO:0140284"(endoplasmic reticulum-endosome membrane contact site)|interpro:IPR000535(Major sperm protein)|interpro:IPR001251(Cellular retinaldehyde-binding/triple function, C-terminal)|interpro:IPR008962(PapD-like)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR036273|interpro:IPR036865|mint:Q8NHP6|rcsb pdb:6TQS|rcsb pdb:6TQT|rcsb pdb:6TQU|reactome:R-HSA-6798695|reactome:R-HSA-9013405|ensembl:ENSG00000130150(gene)|ensembl:ENST00000380492(transcript)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006935"(chemotaxis)|go:"GO:0016020"(membrane)|go:"GO:0035579"(specific granule membrane)|go:"GO:0044232"(organelle membrane contact site) refseq:NP_000173.2|ensembl:ENSG00000084754(gene)|ensembl:ENST00000380649(transcript)|go:"GO:0000062"(fatty-acyl-CoA binding)|go:"GO:0003857"(3-hydroxyacyl-CoA dehydrogenase activity)|go:"GO:0003985"(acetyl-CoA C-acetyltransferase activity)|go:"GO:0004300"(enoyl-CoA hydratase activity)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0006635"(fatty acid beta-oxidation)|go:"GO:0016507"(mitochondrial fatty acid beta-oxidation multienzyme complex)|go:"GO:0016508"(long-chain-enoyl-CoA hydratase activity)|go:"GO:0016509"(long-chain-3-hydroxyacyl-CoA dehydrogenase activity)|go:"GO:0032868"(response to insulin)|go:"GO:0035965"(cardiolipin acyl-chain remodeling)|go:"GO:0042493"|go:"GO:0042645"(mitochondrial nucleoid)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0070403"(NAD+ binding)|interpro:IPR001753(Crotonase, core)|interpro:IPR006108(3-hydroxyacyl-CoA dehydrogenase, C-terminal)|interpro:IPR006176(3-hydroxyacyl-CoA dehydrogenase, NAD binding)|interpro:IPR006180(3-hydroxyacyl-CoA dehydrogenase, conserved site)|interpro:IPR008927(6-phosphogluconate dehydrogenase, C-terminal-like)|interpro:IPR012803(Fatty acid oxidation complex, alpha subunit, mitochondrial)|interpro:IPR018376|interpro:IPR029045|interpro:IPR036291|mint:P40939|rcsb pdb:5ZQZ|rcsb pdb:5ZRV|rcsb pdb:6DV2|reactome:R-HSA-1482798|reactome:R-HSA-77285|reactome:R-HSA-77288|reactome:R-HSA-77305|reactome:R-HSA-77310|reactome:R-HSA-77346|reactome:R-HSA-77348|reactome:R-HSA-77350 - - - figure legend:Fig. 5A, Supp. Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells) - 2020/05/21 2021/04/12 rogid:WEdwMYKpu1uQll5NXnMm4P51R4E9606 rogid:Dr5HQoO5+a+6Q9OtvDIhM4yw4Cg9606 rigid:1P63pNv1yn3F27gcT2OsGH/3EDQ false green fluorescent protein tag:n-n|mutation disrupting interaction strength:406-406,404-404 - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q8NHP6 uniprotkb:Q14849 intact:EBI-2812848|uniprotkb:Q8NA83|uniprotkb:Q8N3H2|ensembl:ENSP00000369860 intact:EBI-9819324|uniprotkb:A8MXA4|uniprotkb:B4DUY1|uniprotkb:F5H0G2|uniprotkb:Q53Y53|uniprotkb:Q96HM9|ensembl:ENSP00000337446 psi-mi:mspd2_human(display_long)|uniprotkb:MOSPD2(gene name)|psi-mi:MOSPD2(display_short) psi-mi:star3_human(display_long)|uniprotkb:STARD3(gene name)|psi-mi:STARD3(display_short)|uniprotkb:CAB1(gene name synonym)|uniprotkb:MLN64(gene name synonym)|uniprotkb:Metastatic lymph node gene 64 protein(gene name synonym)|uniprotkb:Protein CAB1(gene name synonym)|uniprotkb:START domain-containing protein 3(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Di et al. (2018) pubmed:29858488|imex:IM-28178 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-25617558|imex:IM-28178-11 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001170946.1|refseq:NP_689794.1|go:"GO:0090023"(positive regulation of neutrophil chemotaxis)|go:"GO:0090026"(positive regulation of monocyte chemotaxis)|go:"GO:0140284"(endoplasmic reticulum-endosome membrane contact site)|interpro:IPR000535(Major sperm protein)|interpro:IPR001251(Cellular retinaldehyde-binding/triple function, C-terminal)|interpro:IPR008962(PapD-like)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR036273|interpro:IPR036865|mint:Q8NHP6|rcsb pdb:6TQS|rcsb pdb:6TQT|rcsb pdb:6TQU|reactome:R-HSA-6798695|reactome:R-HSA-9013405|ensembl:ENSG00000130150(gene)|ensembl:ENST00000380492(transcript)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006935"(chemotaxis)|go:"GO:0016020"(membrane)|go:"GO:0035579"(specific granule membrane)|go:"GO:0044232"(organelle membrane contact site) refseq:NP_001159409.1|refseq:NP_001159410.1|refseq:NP_006795.3|refseq:XP_016879530.1|ensembl:ENSG00000131748(gene)|ensembl:ENST00000336308(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005768"(endosome)|go:"GO:0005829"(cytosol)|go:"GO:0006629"(lipid metabolic process)|go:"GO:0006701"(progesterone biosynthetic process)|go:"GO:0006839"(mitochondrial transport)|go:"GO:0008202"(steroid metabolic process)|go:"GO:0008203"(cholesterol metabolic process)|go:"GO:0015485"(cholesterol binding)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030301"(cholesterol transport)|go:"GO:0031902"(late endosome membrane)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0044232"(organelle membrane contact site)|go:"GO:0099044"(vesicle tethering to endoplasmic reticulum)|go:"GO:0120020"(cholesterol transfer activity)|go:"GO:0140284"(endoplasmic reticulum-endosome membrane contact site)|interpro:IPR000799(Steroidogenic acute regulatory protein)|interpro:IPR002913(Lipid-binding START)|interpro:IPR019498|interpro:IPR023393|interpro:IPR029867|rcsb pdb:1EM2|rcsb pdb:2I92|rcsb pdb:5I9J|rcsb pdb:6TQR|rcsb pdb:6TQU|reactome:R-HSA-196108 - - - figure legend:Fig. 5A, Supp. Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells) - 2020/05/21 2021/04/12 rogid:WEdwMYKpu1uQll5NXnMm4P51R4E9606 rogid:WukBgAECun0AKrfWzBlepgVuZlE9606 rigid:1P63pNv1yn3F27gcT2OsGH/3EDQ false green fluorescent protein tag:n-n|mutation disrupting interaction strength:406-406,404-404 - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q8NHP6 uniprotkb:H0YLY7 intact:EBI-2812848|uniprotkb:Q8NA83|uniprotkb:Q8N3H2|ensembl:ENSP00000369860 intact:EBI-25618061|ensembl:ENSP00000453392 psi-mi:mspd2_human(display_long)|uniprotkb:MOSPD2(gene name)|psi-mi:MOSPD2(display_short) psi-mi:h0yly7_human(display_long)|uniprotkb:CHP1(gene name)|psi-mi:CHP1(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Di et al. (2018) pubmed:29858488|imex:IM-28178 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-25617558|imex:IM-28178-11 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001170946.1|refseq:NP_689794.1|go:"GO:0090023"(positive regulation of neutrophil chemotaxis)|go:"GO:0090026"(positive regulation of monocyte chemotaxis)|go:"GO:0140284"(endoplasmic reticulum-endosome membrane contact site)|interpro:IPR000535(Major sperm protein)|interpro:IPR001251(Cellular retinaldehyde-binding/triple function, C-terminal)|interpro:IPR008962(PapD-like)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR036273|interpro:IPR036865|mint:Q8NHP6|rcsb pdb:6TQS|rcsb pdb:6TQT|rcsb pdb:6TQU|reactome:R-HSA-6798695|reactome:R-HSA-9013405|ensembl:ENSG00000130150(gene)|ensembl:ENST00000380492(transcript)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006935"(chemotaxis)|go:"GO:0016020"(membrane)|go:"GO:0035579"(specific granule membrane)|go:"GO:0044232"(organelle membrane contact site) ensembl:ENSG00000187446(gene)|ensembl:ENST00000560965(transcript)|go:"GO:0005509"(calcium ion binding)|interpro:IPR002048(Calcium-binding EF-hand)|interpro:IPR011992(EF-Hand type) - - - figure legend:Fig. 5A, Supp. Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells) - 2020/05/21 2021/04/12 rogid:WEdwMYKpu1uQll5NXnMm4P51R4E9606 rogid:CyXH+r+yeNtDSC6/RRMA0jrUolQ9606 rigid:1P63pNv1yn3F27gcT2OsGH/3EDQ false green fluorescent protein tag:n-n|mutation disrupting interaction strength:406-406,404-404 - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q8NHP6 uniprotkb:Q04837 intact:EBI-2812848|uniprotkb:Q8NA83|uniprotkb:Q8N3H2|ensembl:ENSP00000369860 intact:EBI-353460|ensembl:ENSP00000265304|ensembl:ENSP00000419388|ensembl:ENSP00000419541|ensembl:ENSP00000419665|ensembl:ENSP00000420485|ensembl:ENSP00000458815|ensembl:ENSP00000459208|ensembl:ENSP00000459367|ensembl:ENSP00000460028|ensembl:ENSP00000461884|ensembl:ENSP00000480488 psi-mi:mspd2_human(display_long)|uniprotkb:MOSPD2(gene name)|psi-mi:MOSPD2(display_short) psi-mi:ssbp_human(display_long)|uniprotkb:SSBP1(gene name)|psi-mi:SSBP1(display_short)|uniprotkb:SSBP(gene name synonym)|uniprotkb:PWP1-interacting protein 17(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Di et al. (2018) pubmed:29858488|imex:IM-28178 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-25617558|imex:IM-28178-11 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001170946.1|refseq:NP_689794.1|go:"GO:0090023"(positive regulation of neutrophil chemotaxis)|go:"GO:0090026"(positive regulation of monocyte chemotaxis)|go:"GO:0140284"(endoplasmic reticulum-endosome membrane contact site)|interpro:IPR000535(Major sperm protein)|interpro:IPR001251(Cellular retinaldehyde-binding/triple function, C-terminal)|interpro:IPR008962(PapD-like)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR036273|interpro:IPR036865|mint:Q8NHP6|rcsb pdb:6TQS|rcsb pdb:6TQT|rcsb pdb:6TQU|reactome:R-HSA-6798695|reactome:R-HSA-9013405|ensembl:ENSG00000130150(gene)|ensembl:ENST00000380492(transcript)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006935"(chemotaxis)|go:"GO:0016020"(membrane)|go:"GO:0035579"(specific granule membrane)|go:"GO:0044232"(organelle membrane contact site) refseq:NP_003134.1|refseq:NP_001243439.1|refseq:NP_001243440.1|refseq:NP_001243441.1|refseq:NP_001243442.1|ensembl:ENSG00000106028(gene)|ensembl:ENSG00000262771(gene)|ensembl:ENST00000265304(transcript)|ensembl:ENST00000465582(transcript)|ensembl:ENST00000481508(transcript)|ensembl:ENST00000484178(transcript)|ensembl:ENST00000498107(transcript)|ensembl:ENST00000570667(transcript)|ensembl:ENST00000571430(transcript)|ensembl:ENST00000574199(transcript)|ensembl:ENST00000575059(transcript)|ensembl:ENST00000576834(transcript)|ensembl:ENST00000612337(transcript)|go:"GO:0003682"(chromatin binding)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005739"(mitochondrion)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0006264"(mitochondrial DNA replication)|go:"GO:0006268"(DNA unwinding involved in DNA replication)|go:"GO:0009295"(nucleoid)|go:"GO:0042645"(mitochondrial nucleoid)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0051096"(positive regulation of helicase activity)|go:"GO:0051289"(protein homotetramerization)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070584"(mitochondrion morphogenesis)|go:"GO:0090297"(positive regulation of mitochondrial DNA replication)|go:"GO:1905776"(positive regulation of DNA helicase activity)|interpro:IPR000424(Primosome PriB/single-strand DNA-binding)|interpro:IPR011344(Single-strand DNA-binding)|interpro:IPR012340(Nucleic acid-binding, OB-fold)|mint:Q04837|rcsb pdb:1S3O|rcsb pdb:2DUD|rcsb pdb:3ULL|rcsb pdb:6RUP|reactome:R-HSA-2151201 - - - figure legend:Fig. 5A, Supp. Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells) - 2020/05/21 2021/04/12 rogid:WEdwMYKpu1uQll5NXnMm4P51R4E9606 rogid:W/7kbgBRtYcjJfr2XbA1OK9BOS49606 rigid:1P63pNv1yn3F27gcT2OsGH/3EDQ false green fluorescent protein tag:n-n|mutation disrupting interaction strength:406-406,404-404 - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q8NHP6 uniprotkb:Q15046 intact:EBI-2812848|uniprotkb:Q8NA83|uniprotkb:Q8N3H2|ensembl:ENSP00000369860 intact:EBI-356367|uniprotkb:A8MSK1|uniprotkb:Q9HB23|uniprotkb:O14946|uniprotkb:Q96J25|ensembl:ENSP00000303043|uniprotkb:D3DUK4 psi-mi:mspd2_human(display_long)|uniprotkb:MOSPD2(gene name)|psi-mi:MOSPD2(display_short) psi-mi:syk_human(display_long)|uniprotkb:KARS1(gene name)|psi-mi:KARS1(display_short)|uniprotkb:KARS(gene name synonym)|uniprotkb:KIAA0070(gene name synonym)|uniprotkb:Lysyl-tRNA synthetase(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Di et al. (2018) pubmed:29858488|imex:IM-28178 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-25617558|imex:IM-28178-11 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001170946.1|refseq:NP_689794.1|go:"GO:0090023"(positive regulation of neutrophil chemotaxis)|go:"GO:0090026"(positive regulation of monocyte chemotaxis)|go:"GO:0140284"(endoplasmic reticulum-endosome membrane contact site)|interpro:IPR000535(Major sperm protein)|interpro:IPR001251(Cellular retinaldehyde-binding/triple function, C-terminal)|interpro:IPR008962(PapD-like)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR036273|interpro:IPR036865|mint:Q8NHP6|rcsb pdb:6TQS|rcsb pdb:6TQT|rcsb pdb:6TQU|reactome:R-HSA-6798695|reactome:R-HSA-9013405|ensembl:ENSG00000130150(gene)|ensembl:ENST00000380492(transcript)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006935"(chemotaxis)|go:"GO:0016020"(membrane)|go:"GO:0035579"(specific granule membrane)|go:"GO:0044232"(organelle membrane contact site) refseq:NP_001123561.1|refseq:NP_005539.1|go:"GO:0016597"(amino acid binding)|go:"GO:0017101"(aminoacyl-tRNA synthetase multienzyme complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043032"(positive regulation of macrophage activation)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0005739"(mitochondrion)|go:"GO:0070371"(ERK1 and ERK2 cascade)|interpro:IPR002313(Lysyl-tRNA synthetase, class II)|interpro:IPR004364("Aminoacyl-tRNA synthetase, class II (D, K and N)")|interpro:IPR004365(Nucleic acid binding, OB-fold, tRNA/helicase-type)|interpro:IPR006195(Aminoacyl-tRNA synthetase, class II)|interpro:IPR012340(Nucleic acid-binding, OB-fold)|interpro:IPR018149|go:"GO:0005759"(mitochondrial matrix)|interpro:IPR034762|interpro:IPR044136|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|mint:Q15046|go:"GO:0006430"(lysyl-tRNA aminoacylation)|go:"GO:0008033"(tRNA processing)|rcsb pdb:3BJU|rcsb pdb:4DPG|go:"GO:0010165"(response to X-ray)|rcsb pdb:4YCU|rcsb pdb:4YCW|rcsb pdb:6CHD|rcsb pdb:6ILD|rcsb pdb:6ILH|rcsb pdb:7EA9|reactome:R-HSA-2408522|reactome:R-HSA-379716|reactome:R-HSA-379726|go:"GO:0015966"(diadenosine tetraphosphate biosynthetic process)|ensembl:ENSG00000065427(gene)|ensembl:ENST00000302445(transcript)|go:"GO:0000049"(tRNA binding)|go:"GO:0002276"(basophil activation involved in immune response)|go:"GO:0002863"(positive regulation of inflammatory response to antigenic stimulus)|go:"GO:0003877"(ATP adenylyltransferase activity)|go:"GO:0004824"(lysine-tRNA ligase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005634"(nucleus)|dip:DIP-29725N - - - figure legend:Fig. 5A, Supp. Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells) - 2020/05/21 2021/04/12 rogid:WEdwMYKpu1uQll5NXnMm4P51R4E9606 rogid:YLjIdoUW7DiNp+Pj1OPg8jhnC5w9606 rigid:1P63pNv1yn3F27gcT2OsGH/3EDQ false green fluorescent protein tag:n-n|mutation disrupting interaction strength:406-406,404-404 - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q8NHP6 uniprotkb:Q96I24 intact:EBI-2812848|uniprotkb:Q8NA83|uniprotkb:Q8N3H2|ensembl:ENSP00000369860 intact:EBI-954200|ensembl:ENSP00000318177|uniprotkb:Q92946|uniprotkb:Q9BVB6|intact:EBI-1760333|intact:EBI-1965411|uniprotkb:A3KFL0|uniprotkb:A3KFK8 psi-mi:mspd2_human(display_long)|uniprotkb:MOSPD2(gene name)|psi-mi:MOSPD2(display_short) psi-mi:fubp3_human(display_long)|uniprotkb:FUBP3(gene name)|psi-mi:FUBP3(display_short)|uniprotkb:FBP3(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Di et al. (2018) pubmed:29858488|imex:IM-28178 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-25617558|imex:IM-28178-11 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001170946.1|refseq:NP_689794.1|go:"GO:0090023"(positive regulation of neutrophil chemotaxis)|go:"GO:0090026"(positive regulation of monocyte chemotaxis)|go:"GO:0140284"(endoplasmic reticulum-endosome membrane contact site)|interpro:IPR000535(Major sperm protein)|interpro:IPR001251(Cellular retinaldehyde-binding/triple function, C-terminal)|interpro:IPR008962(PapD-like)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR036273|interpro:IPR036865|mint:Q8NHP6|rcsb pdb:6TQS|rcsb pdb:6TQT|rcsb pdb:6TQU|reactome:R-HSA-6798695|reactome:R-HSA-9013405|ensembl:ENSG00000130150(gene)|ensembl:ENST00000380492(transcript)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006935"(chemotaxis)|go:"GO:0016020"(membrane)|go:"GO:0035579"(specific granule membrane)|go:"GO:0044232"(organelle membrane contact site) ensembl:ENSG00000107164(gene)|ensembl:ENST00000319725(transcript)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0016020"(membrane)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|interpro:IPR004087(K Homology)|interpro:IPR004088(K Homology, type 1)|interpro:IPR036612|mint:Q96I24|refseq:NP_003925.1|dip:DIP-50124N - - - figure legend:Fig. 5A, Supp. Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells) - 2020/05/21 2021/04/12 rogid:WEdwMYKpu1uQll5NXnMm4P51R4E9606 rogid:xdCa+teqFaSxKNTpCJWQ5gcd0sQ9606 rigid:1P63pNv1yn3F27gcT2OsGH/3EDQ false green fluorescent protein tag:n-n|mutation disrupting interaction strength:406-406,404-404 - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q8NHP6 uniprotkb:C9JZ20 intact:EBI-2812848|uniprotkb:Q8NA83|uniprotkb:Q8N3H2|ensembl:ENSP00000369860 intact:EBI-25618050|ensembl:ENSP00000407828 psi-mi:mspd2_human(display_long)|uniprotkb:MOSPD2(gene name)|psi-mi:MOSPD2(display_short) psi-mi:c9jz20_human(display_long)|uniprotkb:PHB(gene name)|psi-mi:PHB(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Di et al. (2018) pubmed:29858488|imex:IM-28178 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-25617558|imex:IM-28178-11 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001170946.1|refseq:NP_689794.1|go:"GO:0090023"(positive regulation of neutrophil chemotaxis)|go:"GO:0090026"(positive regulation of monocyte chemotaxis)|go:"GO:0140284"(endoplasmic reticulum-endosome membrane contact site)|interpro:IPR000535(Major sperm protein)|interpro:IPR001251(Cellular retinaldehyde-binding/triple function, C-terminal)|interpro:IPR008962(PapD-like)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR036273|interpro:IPR036865|mint:Q8NHP6|rcsb pdb:6TQS|rcsb pdb:6TQT|rcsb pdb:6TQU|reactome:R-HSA-6798695|reactome:R-HSA-9013405|ensembl:ENSG00000130150(gene)|ensembl:ENST00000380492(transcript)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006935"(chemotaxis)|go:"GO:0016020"(membrane)|go:"GO:0035579"(specific granule membrane)|go:"GO:0044232"(organelle membrane contact site) ensembl:ENSG00000167085(gene)|ensembl:ENST00000446735(transcript)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005886"(plasma membrane)|interpro:IPR000163(Prohibitin)|interpro:IPR001107(Band 7 protein)|interpro:IPR036013 - - - figure legend:Fig. 5A, Supp. Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells) - 2020/05/21 2021/04/12 rogid:WEdwMYKpu1uQll5NXnMm4P51R4E9606 rogid:Mskx3+zyHpYWOhcBKn6Qms4w1dk9606 rigid:1P63pNv1yn3F27gcT2OsGH/3EDQ false green fluorescent protein tag:n-n|mutation disrupting interaction strength:406-406,404-404 - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q8NHP6 uniprotkb:P06899 intact:EBI-2812848|uniprotkb:Q8NA83|uniprotkb:Q8N3H2|ensembl:ENSP00000369860 intact:EBI-6150252|uniprotkb:B2R4J4|uniprotkb:O60816|ensembl:ENSP00000342886|ensembl:ENSP00000476136 psi-mi:mspd2_human(display_long)|uniprotkb:MOSPD2(gene name)|psi-mi:MOSPD2(display_short) psi-mi:h2b1j_human(display_long)|uniprotkb:H2BC11(gene name)|psi-mi:H2BC11(display_short)|uniprotkb:H2BFR(gene name synonym)|uniprotkb:HIST1H2BJ(gene name synonym)|uniprotkb:Histone H2B.1(gene name synonym)|uniprotkb:Histone H2B.r(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Di et al. (2018) pubmed:29858488|imex:IM-28178 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-25617558|imex:IM-28178-11 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001170946.1|refseq:NP_689794.1|go:"GO:0090023"(positive regulation of neutrophil chemotaxis)|go:"GO:0090026"(positive regulation of monocyte chemotaxis)|go:"GO:0140284"(endoplasmic reticulum-endosome membrane contact site)|interpro:IPR000535(Major sperm protein)|interpro:IPR001251(Cellular retinaldehyde-binding/triple function, C-terminal)|interpro:IPR008962(PapD-like)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR036273|interpro:IPR036865|mint:Q8NHP6|rcsb pdb:6TQS|rcsb pdb:6TQT|rcsb pdb:6TQU|reactome:R-HSA-6798695|reactome:R-HSA-9013405|ensembl:ENSG00000130150(gene)|ensembl:ENST00000380492(transcript)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006935"(chemotaxis)|go:"GO:0016020"(membrane)|go:"GO:0035579"(specific granule membrane)|go:"GO:0044232"(organelle membrane contact site) refseq:NP_066402.2|dip:DIP-421N|ensembl:ENSG00000124635(gene)|ensembl:ENST00000339812(transcript)|ensembl:ENST00000607124(transcript)|go:"GO:0000786"(nucleosome)|go:"GO:0001530"(lipopolysaccharide binding)|go:"GO:0002227"(innate immune response in mucosa)|go:"GO:0003677"(DNA binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006334"(nucleosome assembly)|go:"GO:0010804"(negative regulation of tumor necrosis factor-mediated signaling pathway)|go:"GO:0019731"(antibacterial humoral response)|go:"GO:0031640"(killing of cells of another organism)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0050829"(defense response to Gram-negative bacterium)|go:"GO:0050830"(defense response to Gram-positive bacterium)|go:"GO:0061844"(antimicrobial humoral immune response mediated by antimicrobial peptide)|interpro:IPR000558(Histone H2B)|interpro:IPR007125(Histone core)|interpro:IPR009072(Histone-fold)|mint:P06899|rcsb pdb:2RVQ|rcsb pdb:3A6N|rcsb pdb:3AFA|rcsb pdb:3AN2|rcsb pdb:3AV1|rcsb pdb:3AV2|rcsb pdb:3AYW|rcsb pdb:3AZE|rcsb pdb:3AZF|rcsb pdb:3AZG|rcsb pdb:3AZH|rcsb pdb:3AZI|rcsb pdb:3AZJ|rcsb pdb:3AZK|rcsb pdb:3AZL|rcsb pdb:3AZM|rcsb pdb:3AZN|rcsb pdb:3W96|rcsb pdb:3W97|rcsb pdb:3W98|rcsb pdb:3W99|rcsb pdb:3WAA|rcsb pdb:3WTP|rcsb pdb:4CAY|rcsb pdb:4YM5|rcsb pdb:4YM6|rcsb pdb:4Z5T|rcsb pdb:5AV5|rcsb pdb:5AV6|rcsb pdb:5AV8|rcsb pdb:5AV9|rcsb pdb:5AVB|rcsb pdb:5AVC|rcsb pdb:5AY8|rcsb pdb:5B0Y|rcsb pdb:5B0Z|rcsb pdb:5B24|rcsb pdb:5B2I|rcsb pdb:5B2J|rcsb pdb:5B31|rcsb pdb:5B32|rcsb pdb:5B33|rcsb pdb:5B40|rcsb pdb:5CPI|rcsb pdb:5CPJ|rcsb pdb:5CPK|rcsb pdb:5FUG|rcsb pdb:5GSE|rcsb pdb:5GTC|rcsb pdb:5GXQ|rcsb pdb:5JRG|rcsb pdb:5VEY|rcsb pdb:5X7X|rcsb pdb:5XF3|rcsb pdb:5XF4|rcsb pdb:5XF5|rcsb pdb:5Y0C|rcsb pdb:5Y0D|rcsb pdb:5Z23|rcsb pdb:5Z30|rcsb pdb:5ZBX|rcsb pdb:6A5L|rcsb pdb:6A5O|rcsb pdb:6A5P|rcsb pdb:6A5R|rcsb pdb:6A5T|rcsb pdb:6A5U|rcsb pdb:6BUZ|rcsb pdb:6E0C|rcsb pdb:6E0P|rcsb pdb:6HKT|rcsb pdb:6HTS|rcsb pdb:6INQ|rcsb pdb:6IPU|rcsb pdb:6IQ4|rcsb pdb:6IR9|rcsb pdb:6J4W|rcsb pdb:6J4X|rcsb pdb:6J4Y|rcsb pdb:6J4Z|rcsb pdb:6J50|rcsb pdb:6J51|rcsb pdb:6JOU|rcsb pdb:6JR0|rcsb pdb:6JR1|rcsb pdb:6JXD|rcsb pdb:6K1I|rcsb pdb:6K1J|rcsb pdb:6K1K|rcsb pdb:6KVD|rcsb pdb:6KXV|rcsb pdb:6L49|rcsb pdb:6L4A|rcsb pdb:6L9Z|rcsb pdb:6LA2|rcsb pdb:6LA8|rcsb pdb:6LA9|rcsb pdb:6LAB|rcsb pdb:6LER|rcsb pdb:6M3V|rcsb pdb:6M44|rcsb pdb:6O1D|rcsb pdb:6R8Y|rcsb pdb:6R8Z|rcsb pdb:6R90|rcsb pdb:6R91|rcsb pdb:6R92|rcsb pdb:6R93|rcsb pdb:6R94|rcsb pdb:6T90|rcsb pdb:6T93|rcsb pdb:6USJ|rcsb pdb:6V2K|rcsb pdb:6YOV|rcsb pdb:7BY0|rcsb pdb:7C0M|rcsb pdb:7CCQ|rcsb pdb:7CCR|rcsb pdb:7D1Z|rcsb pdb:7D20|rcsb pdb:7K5X|rcsb pdb:3WA9|rcsb pdb:7K5Y|rcsb pdb:7K60|rcsb pdb:7K61|rcsb pdb:7K63|rcsb pdb:7LYC|reactome:R-HSA-110328|reactome:R-HSA-110329|reactome:R-HSA-110330|reactome:R-HSA-110331|reactome:R-HSA-1221632|reactome:R-HSA-171306|reactome:R-HSA-1912408|reactome:R-HSA-201722|reactome:R-HSA-212300|reactome:R-HSA-2299718|reactome:R-HSA-2559580|reactome:R-HSA-2559582|reactome:R-HSA-2559586|reactome:R-HSA-3214815|reactome:R-HSA-3214847|reactome:R-HSA-427359|reactome:R-HSA-427389|reactome:R-HSA-427413|reactome:R-HSA-5250924|reactome:R-HSA-5334118|reactome:R-HSA-5578749|reactome:R-HSA-5617472|reactome:R-HSA-5625886|reactome:R-HSA-5689880|reactome:R-HSA-5693565|reactome:R-HSA-5693571|reactome:R-HSA-5693607|reactome:R-HSA-606279|reactome:R-HSA-69473|reactome:R-HSA-73728|reactome:R-HSA-73772|reactome:R-HSA-8866654|reactome:R-HSA-8936459|reactome:R-HSA-8939236|reactome:R-HSA-9018519|reactome:R-HSA-912446|reactome:R-HSA-9609690|reactome:R-HSA-9610379|reactome:R-HSA-9616222|reactome:R-HSA-9670095|reactome:R-HSA-9710421|reactome:R-HSA-977225 - - - figure legend:Fig. 5A, Supp. Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells) - 2020/05/21 2021/04/12 rogid:WEdwMYKpu1uQll5NXnMm4P51R4E9606 rogid:74GQlSjGG1Ez6Uog74VXPLryKBc9606 rigid:1P63pNv1yn3F27gcT2OsGH/3EDQ false green fluorescent protein tag:n-n|mutation disrupting interaction strength:406-406,404-404 - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q8NHP6 uniprotkb:Q9H2M9 intact:EBI-2812848|uniprotkb:Q8NA83|uniprotkb:Q8N3H2|ensembl:ENSP00000369860 intact:EBI-536107|uniprotkb:O75872|uniprotkb:Q9HAB0|uniprotkb:Q9UFJ7|uniprotkb:Q9UQ15|ensembl:ENSP00000351832|uniprotkb:A6H8V0 psi-mi:mspd2_human(display_long)|uniprotkb:MOSPD2(gene name)|psi-mi:MOSPD2(display_short) psi-mi:rbgpr_human(display_long)|uniprotkb:Rab3 GTPase-activating protein 150 kDa subunit(gene name synonym)|uniprotkb:Rab3-GAP p150(gene name synonym)|uniprotkb:Rab3-GAP regulatory subunit(gene name synonym)|uniprotkb:RGAP-iso(gene name synonym)|uniprotkb:KIAA0839(gene name synonym)|uniprotkb:RAB3GAP2(gene name)|psi-mi:RAB3GAP2(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Di et al. (2018) pubmed:29858488|imex:IM-28178 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-25617558|imex:IM-28178-11 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001170946.1|refseq:NP_689794.1|go:"GO:0090023"(positive regulation of neutrophil chemotaxis)|go:"GO:0090026"(positive regulation of monocyte chemotaxis)|go:"GO:0140284"(endoplasmic reticulum-endosome membrane contact site)|interpro:IPR000535(Major sperm protein)|interpro:IPR001251(Cellular retinaldehyde-binding/triple function, C-terminal)|interpro:IPR008962(PapD-like)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR036273|interpro:IPR036865|mint:Q8NHP6|rcsb pdb:6TQS|rcsb pdb:6TQT|rcsb pdb:6TQU|reactome:R-HSA-6798695|reactome:R-HSA-9013405|ensembl:ENSG00000130150(gene)|ensembl:ENST00000380492(transcript)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006935"(chemotaxis)|go:"GO:0016020"(membrane)|go:"GO:0035579"(specific granule membrane)|go:"GO:0044232"(organelle membrane contact site) refseq:NP_036546.2|ensembl:ENSG00000118873(gene)|ensembl:ENST00000358951(transcript)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0008047"(enzyme activator activity)|go:"GO:0030234"(enzyme regulator activity)|go:"GO:0031267"(small GTPase binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0043087"(regulation of GTPase activity)|go:"GO:0097051"(establishment of protein localization to endoplasmic reticulum membrane)|go:"GO:1903061"(positive regulation of protein lipidation)|go:"GO:1903373"(positive regulation of endoplasmic reticulum tubular network organization)|go:"GO:2000786"(positive regulation of autophagosome assembly)|interpro:IPR026059|interpro:IPR029257|interpro:IPR032839|mint:Q9H2M9|reactome:R-HSA-6811436|reactome:R-HSA-8876198 - - - figure legend:Fig. 5A, Supp. Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells) - 2020/05/21 2021/04/12 rogid:WEdwMYKpu1uQll5NXnMm4P51R4E9606 rogid:Xix4Ih2/G7zRKyw0kxH0GlV4j4o9606 rigid:1P63pNv1yn3F27gcT2OsGH/3EDQ false green fluorescent protein tag:n-n|mutation disrupting interaction strength:406-406,404-404 - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q8NHP6 uniprotkb:Q13885 intact:EBI-2812848|uniprotkb:Q8NA83|uniprotkb:Q8N3H2|ensembl:ENSP00000369860 intact:EBI-711595|ensembl:ENSP00000369703|uniprotkb:Q6FGZ8|uniprotkb:Q8IWR2 psi-mi:mspd2_human(display_long)|uniprotkb:MOSPD2(gene name)|psi-mi:MOSPD2(display_short) psi-mi:tbb2a_human(display_long)|uniprotkb:TUBB2A(gene name)|psi-mi:TUBB2A(display_short)|uniprotkb:TUBB2(gene name synonym)|uniprotkb:Tubulin beta class IIa(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Di et al. (2018) pubmed:29858488|imex:IM-28178 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-25617558|imex:IM-28178-11 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001170946.1|refseq:NP_689794.1|go:"GO:0090023"(positive regulation of neutrophil chemotaxis)|go:"GO:0090026"(positive regulation of monocyte chemotaxis)|go:"GO:0140284"(endoplasmic reticulum-endosome membrane contact site)|interpro:IPR000535(Major sperm protein)|interpro:IPR001251(Cellular retinaldehyde-binding/triple function, C-terminal)|interpro:IPR008962(PapD-like)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR036273|interpro:IPR036865|mint:Q8NHP6|rcsb pdb:6TQS|rcsb pdb:6TQT|rcsb pdb:6TQU|reactome:R-HSA-6798695|reactome:R-HSA-9013405|ensembl:ENSG00000130150(gene)|ensembl:ENST00000380492(transcript)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006935"(chemotaxis)|go:"GO:0016020"(membrane)|go:"GO:0035579"(specific granule membrane)|go:"GO:0044232"(organelle membrane contact site) reactome:R-HSA-389960|reactome:R-HSA-389977|reactome:R-HSA-437239|reactome:R-HSA-5610787|reactome:R-HSA-5617833|reactome:R-HSA-5620924|reactome:R-HSA-5626467|reactome:R-HSA-5663220|reactome:R-HSA-6807878|reactome:R-HSA-6811434|reactome:R-HSA-6811436|reactome:R-HSA-68877|reactome:R-HSA-8852276|reactome:R-HSA-8955332|reactome:R-HSA-9609690|reactome:R-HSA-9609736|reactome:R-HSA-9619483|reactome:R-HSA-9646399|reactome:R-HSA-9648025|reactome:R-HSA-389957|reactome:R-HSA-983189|reactome:R-HSA-9668328|ensembl:ENSG00000137267(gene)|ensembl:ENST00000333628(transcript)|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0001764"(neuron migration)|go:"GO:0005200"(structural constituent of cytoskeleton)|go:"GO:0005525"(GTP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005874"(microtubule)|go:"GO:0070062"(extracellular exosome)|go:"GO:1903561"(extracellular vesicle)|interpro:IPR000217(Tubulin)|interpro:IPR002453(Beta tubulin)|interpro:IPR003008(Tubulin/FtsZ, GTPase)|interpro:IPR008280(Tubulin/FtsZ, C-terminal)|interpro:IPR013838(Beta tubulin, autoregulation binding site)|interpro:IPR017975|interpro:IPR018316|interpro:IPR023123|interpro:IPR036525|interpro:IPR037103|mint:Q13885|reactome:R-HSA-1445148|reactome:R-HSA-190840|reactome:R-HSA-190861|reactome:R-HSA-2132295|reactome:R-HSA-2467813|reactome:R-HSA-2500257|reactome:R-HSA-3371497|reactome:R-HSA-380320|refseq:NP_001060.1|refseq:NP_001297244.1 - - - figure legend:Fig. 5A, Supp. Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells) - 2020/05/21 2021/04/12 rogid:WEdwMYKpu1uQll5NXnMm4P51R4E9606 rogid:XN9uTGU0KxQjMod0AGnM+XJoHyk9606 rigid:1P63pNv1yn3F27gcT2OsGH/3EDQ false green fluorescent protein tag:n-n|mutation disrupting interaction strength:406-406,404-404 - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q8NHP6 uniprotkb:H9KV75 intact:EBI-2812848|uniprotkb:Q8NA83|uniprotkb:Q8N3H2|ensembl:ENSP00000369860 intact:EBI-25618030|ensembl:ENSP00000366035|ensembl:ENSP00000506977 psi-mi:mspd2_human(display_long)|uniprotkb:MOSPD2(gene name)|psi-mi:MOSPD2(display_short) psi-mi:h9kv75_human(display_long)|uniprotkb:ACTN1(gene name)|psi-mi:ACTN1(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Di et al. (2018) pubmed:29858488|imex:IM-28178 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-25617558|imex:IM-28178-11 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001170946.1|refseq:NP_689794.1|go:"GO:0090023"(positive regulation of neutrophil chemotaxis)|go:"GO:0090026"(positive regulation of monocyte chemotaxis)|go:"GO:0140284"(endoplasmic reticulum-endosome membrane contact site)|interpro:IPR000535(Major sperm protein)|interpro:IPR001251(Cellular retinaldehyde-binding/triple function, C-terminal)|interpro:IPR008962(PapD-like)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR036273|interpro:IPR036865|mint:Q8NHP6|rcsb pdb:6TQS|rcsb pdb:6TQT|rcsb pdb:6TQU|reactome:R-HSA-6798695|reactome:R-HSA-9013405|ensembl:ENSG00000130150(gene)|ensembl:ENST00000380492(transcript)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006935"(chemotaxis)|go:"GO:0016020"(membrane)|go:"GO:0035579"(specific granule membrane)|go:"GO:0044232"(organelle membrane contact site) go:"GO:0003779"(actin binding)|go:"GO:0005509"(calcium ion binding)|interpro:IPR001589(Actinin-type, actin-binding, conserved site)|interpro:IPR001715(Calponin-like actin-binding)|interpro:IPR002017(Spectrin repeat)|interpro:IPR002048(Calcium-binding EF-hand)|interpro:IPR011992(EF-Hand type)|interpro:IPR014837(EF-hand, Ca insensitive)|interpro:IPR018159|interpro:IPR036872|ensembl:ENST00000683225(transcript)|ensembl:ENSG00000072110(gene)|ensembl:ENST00000376839(transcript) - - - figure legend:Fig. 5A, Supp. Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells) - 2020/05/21 2021/04/12 rogid:WEdwMYKpu1uQll5NXnMm4P51R4E9606 rogid:FJWOyLhBT0Pj4+8akML7k1MJg0M9606 rigid:1P63pNv1yn3F27gcT2OsGH/3EDQ false green fluorescent protein tag:n-n|mutation disrupting interaction strength:406-406,404-404 - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q8NHP6 uniprotkb:P62701 intact:EBI-2812848|uniprotkb:Q8NA83|uniprotkb:Q8N3H2|ensembl:ENSP00000369860 intact:EBI-354303|uniprotkb:P12631|uniprotkb:P12750|uniprotkb:P27576|uniprotkb:Q14727|uniprotkb:P55831|uniprotkb:Q6IPY4|ensembl:ENSP00000362744 psi-mi:mspd2_human(display_long)|uniprotkb:MOSPD2(gene name)|psi-mi:MOSPD2(display_short) psi-mi:rs4x_human(display_long)|uniprotkb:RPS4X(gene name)|psi-mi:RPS4X(display_short)|uniprotkb:CCG2(gene name synonym)|uniprotkb:RPS4(gene name synonym)|uniprotkb:SCAR(gene name synonym)|uniprotkb:Single copy abundant mRNA protein(gene name synonym)|uniprotkb:SCR10(gene name synonym)|uniprotkb:Small ribosomal subunit protein eS4(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Di et al. (2018) pubmed:29858488|imex:IM-28178 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-25617558|imex:IM-28178-11 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001170946.1|refseq:NP_689794.1|go:"GO:0090023"(positive regulation of neutrophil chemotaxis)|go:"GO:0090026"(positive regulation of monocyte chemotaxis)|go:"GO:0140284"(endoplasmic reticulum-endosome membrane contact site)|interpro:IPR000535(Major sperm protein)|interpro:IPR001251(Cellular retinaldehyde-binding/triple function, C-terminal)|interpro:IPR008962(PapD-like)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR036273|interpro:IPR036865|mint:Q8NHP6|rcsb pdb:6TQS|rcsb pdb:6TQT|rcsb pdb:6TQU|reactome:R-HSA-6798695|reactome:R-HSA-9013405|ensembl:ENSG00000130150(gene)|ensembl:ENST00000380492(transcript)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006935"(chemotaxis)|go:"GO:0016020"(membrane)|go:"GO:0035579"(specific granule membrane)|go:"GO:0044232"(organelle membrane contact site) refseq:NP_000998.1|rcsb pdb:6OLI|rcsb pdb:6OM0|rcsb pdb:6OM7|rcsb pdb:6QZP|rcsb pdb:6XA1|rcsb pdb:6Y0G|rcsb pdb:6Y2L|rcsb pdb:6Y57|rcsb pdb:6YBW|rcsb pdb:6Z6L|rcsb pdb:6Z6M|rcsb pdb:6Z6N|rcsb pdb:6ZLW|rcsb pdb:6ZM7|rcsb pdb:6ZME|rcsb pdb:6ZMI|rcsb pdb:6ZMO|rcsb pdb:6ZMT|rcsb pdb:6ZMW|rcsb pdb:6ZN5|rcsb pdb:6ZOJ|rcsb pdb:6ZOK|rcsb pdb:6ZON|rcsb pdb:6ZP4|rcsb pdb:6ZUO|rcsb pdb:6ZV6|rcsb pdb:6ZVH|rcsb pdb:6ZVJ|rcsb pdb:6ZXD|rcsb pdb:6ZXE|rcsb pdb:6ZXF|rcsb pdb:6ZXG|rcsb pdb:6ZXH|rcsb pdb:7A09|rcsb pdb:7K5I|reactome:R-HSA-156827|reactome:R-HSA-156902|reactome:R-HSA-1799339|reactome:R-HSA-192823|reactome:R-HSA-2408557|reactome:R-HSA-6791226|reactome:R-HSA-72649|reactome:R-HSA-72689|reactome:R-HSA-72695|reactome:R-HSA-72702|reactome:R-HSA-72706|reactome:R-HSA-72764|reactome:R-HSA-9010553|reactome:R-HSA-9633012|reactome:R-HSA-975956|reactome:R-HSA-975957|ensembl:ENSG00000198034(gene)|ensembl:ENST00000316084(transcript)|go:"GO:0002181"(cytoplasmic translation)|go:"GO:0003723"(RNA binding)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005840"(ribosome)|go:"GO:0005844"(polysome)|go:"GO:0005925"(focal adhesion)|go:"GO:0006412"(translation)|go:"GO:0007275"(multicellular organism development)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0015935"(small ribosomal subunit)|go:"GO:0016020"(membrane)|go:"GO:0019843"(rRNA binding)|go:"GO:0022626"(cytosolic ribosome)|go:"GO:0022627"(cytosolic small ribosomal subunit)|go:"GO:0036464"(cytoplasmic ribonucleoprotein granule)|go:"GO:0045202"(synapse)|go:"GO:0070062"(extracellular exosome)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR000876(Ribosomal protein S4e)|interpro:IPR002942(RNA-binding S4)|interpro:IPR005824(KOW)|interpro:IPR013843(Ribosomal protein S4e, N-terminal)|interpro:IPR013845(Ribosomal protein S4e, central)|interpro:IPR014722(Translation protein SH3-like, subgroup)|interpro:IPR018199|interpro:IPR032277|interpro:IPR036986|interpro:IPR038237|interpro:IPR041982|mint:P62701|rcsb pdb:4UG0|rcsb pdb:4V6X|rcsb pdb:5A2Q|rcsb pdb:5LKS|rcsb pdb:5OA3|rcsb pdb:5T2C|rcsb pdb:5VYC|rcsb pdb:6EK0|rcsb pdb:6FEC|go:"GO:0045727"(positive regulation of translation)|rcsb pdb:6G18|rcsb pdb:6G4S|rcsb pdb:6G4W|rcsb pdb:6G51|rcsb pdb:6G53|rcsb pdb:6G5H|rcsb pdb:6G5I|rcsb pdb:6IP5|rcsb pdb:6IP6|rcsb pdb:6IP8|rcsb pdb:6OLE|rcsb pdb:6OLF - - - figure legend:Fig. 5A, Supp. Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells) - 2020/05/21 2021/04/12 rogid:WEdwMYKpu1uQll5NXnMm4P51R4E9606 rogid:2ZuLXqBSDkK0CtN3mnIDoFAR8yI9606 rigid:1P63pNv1yn3F27gcT2OsGH/3EDQ false green fluorescent protein tag:n-n|mutation disrupting interaction strength:406-406,404-404 - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q8NHP6 uniprotkb:Q96IR7 intact:EBI-2812848|uniprotkb:Q8NA83|uniprotkb:Q8N3H2|ensembl:ENSP00000369860 intact:EBI-25618012|ensembl:ENSP00000335060|uniprotkb:B2R9B0 psi-mi:mspd2_human(display_long)|uniprotkb:MOSPD2(gene name)|psi-mi:MOSPD2(display_short) psi-mi:hpdl_human(display_long)|uniprotkb:HPDL(gene name)|psi-mi:HPDL(display_short)|uniprotkb:GLOXD1(gene name synonym)|uniprotkb:Glyoxalase domain-containing protein 1(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Di et al. (2018) pubmed:29858488|imex:IM-28178 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-25617558|imex:IM-28178-11 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001170946.1|refseq:NP_689794.1|go:"GO:0090023"(positive regulation of neutrophil chemotaxis)|go:"GO:0090026"(positive regulation of monocyte chemotaxis)|go:"GO:0140284"(endoplasmic reticulum-endosome membrane contact site)|interpro:IPR000535(Major sperm protein)|interpro:IPR001251(Cellular retinaldehyde-binding/triple function, C-terminal)|interpro:IPR008962(PapD-like)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR036273|interpro:IPR036865|mint:Q8NHP6|rcsb pdb:6TQS|rcsb pdb:6TQT|rcsb pdb:6TQU|reactome:R-HSA-6798695|reactome:R-HSA-9013405|ensembl:ENSG00000130150(gene)|ensembl:ENST00000380492(transcript)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006935"(chemotaxis)|go:"GO:0016020"(membrane)|go:"GO:0035579"(specific granule membrane)|go:"GO:0044232"(organelle membrane contact site) ensembl:ENSG00000186603(gene)|ensembl:ENST00000334815(transcript)|go:"GO:0003868"(4-hydroxyphenylpyruvate dioxygenase activity)|go:"GO:0005739"(mitochondrion)|go:"GO:0009072"(aromatic amino acid family metabolic process)|go:"GO:0046872"(metal ion binding)|interpro:IPR005956(4-hydroxyphenylpyruvate dioxygenase)|interpro:IPR029068|interpro:IPR037523|interpro:IPR041735|interpro:IPR041736|refseq:NP_116145.1 - - - figure legend:Fig. 5A, Supp. Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells) - 2020/05/21 2021/04/12 rogid:WEdwMYKpu1uQll5NXnMm4P51R4E9606 rogid:3gp85FhNz+SvfAmYcLxBiM6iavc9606 rigid:1P63pNv1yn3F27gcT2OsGH/3EDQ false green fluorescent protein tag:n-n|mutation disrupting interaction strength:406-406,404-404 - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q8NHP6 uniprotkb:O95249 intact:EBI-2812848|uniprotkb:Q8NA83|uniprotkb:Q8N3H2|ensembl:ENSP00000369860 intact:EBI-3235244|ensembl:ENSP00000225724|uniprotkb:O75392|uniprotkb:J3KST5 psi-mi:mspd2_human(display_long)|uniprotkb:MOSPD2(gene name)|psi-mi:MOSPD2(display_short) psi-mi:gosr1_human(display_long)|uniprotkb:GOSR1(gene name)|psi-mi:GOSR1(display_short)|uniprotkb:GS28(gene name synonym)|uniprotkb:28 kDa Golgi SNARE protein(gene name synonym)|uniprotkb:28 kDa cis-Golgi SNARE p28(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Di et al. (2018) pubmed:29858488|imex:IM-28178 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-25617558|imex:IM-28178-11 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001170946.1|refseq:NP_689794.1|go:"GO:0090023"(positive regulation of neutrophil chemotaxis)|go:"GO:0090026"(positive regulation of monocyte chemotaxis)|go:"GO:0140284"(endoplasmic reticulum-endosome membrane contact site)|interpro:IPR000535(Major sperm protein)|interpro:IPR001251(Cellular retinaldehyde-binding/triple function, C-terminal)|interpro:IPR008962(PapD-like)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR036273|interpro:IPR036865|mint:Q8NHP6|rcsb pdb:6TQS|rcsb pdb:6TQT|rcsb pdb:6TQU|reactome:R-HSA-6798695|reactome:R-HSA-9013405|ensembl:ENSG00000130150(gene)|ensembl:ENST00000380492(transcript)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006935"(chemotaxis)|go:"GO:0016020"(membrane)|go:"GO:0035579"(specific granule membrane)|go:"GO:0044232"(organelle membrane contact site) ensembl:ENSG00000108587(gene)|ensembl:ENST00000225724(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0005484"(SNAP receptor activity)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005797"(Golgi medial cisterna)|go:"GO:0005801"(cis-Golgi network)|go:"GO:0005829"(cytosol)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0006891"(intra-Golgi vesicle-mediated transport)|go:"GO:0006906"(vesicle fusion)|go:"GO:0015031"(protein transport)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030133"(transport vesicle)|go:"GO:0031201"(SNARE complex)|go:"GO:0042147"(retrograde transport, endosome to Golgi)|go:"GO:0048209"(regulation of vesicle targeting, to, from or within Golgi)|interpro:IPR023601|mint:O95249|reactome:R-HSA-6807878|reactome:R-HSA-6811438|refseq:NP_001007025.1|refseq:NP_001007026.1|refseq:NP_004862.1|refseq:XP_005258129.1 - - - figure legend:Fig. 5A, Supp. Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells) - 2020/05/21 2021/04/12 rogid:WEdwMYKpu1uQll5NXnMm4P51R4E9606 rogid:zebOuVPnYg5z3XqCa5rMI2IR/jY9606 rigid:1P63pNv1yn3F27gcT2OsGH/3EDQ false green fluorescent protein tag:n-n|mutation disrupting interaction strength:406-406,404-404 - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q8NHP6 intact:EBI-25618002 intact:EBI-2812848|uniprotkb:Q8NA83|uniprotkb:Q8N3H2|ensembl:ENSP00000369860 - psi-mi:mspd2_human(display_long)|uniprotkb:MOSPD2(gene name)|psi-mi:MOSPD2(display_short) psi-mi:f5gyq2_human(display_short)|psi-mi:EBI-25618002(display_long)|uniprotkb:TRMT112(gene name)|psi-mi:TRMT112(display_short)|uniprotkb:tRNA methyltransferase 112 homolog(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Di et al. (2018) pubmed:29858488|imex:IM-28178 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-25617558|imex:IM-28178-11 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001170946.1|refseq:NP_689794.1|go:"GO:0090023"(positive regulation of neutrophil chemotaxis)|go:"GO:0090026"(positive regulation of monocyte chemotaxis)|go:"GO:0140284"(endoplasmic reticulum-endosome membrane contact site)|interpro:IPR000535(Major sperm protein)|interpro:IPR001251(Cellular retinaldehyde-binding/triple function, C-terminal)|interpro:IPR008962(PapD-like)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR036273|interpro:IPR036865|mint:Q8NHP6|rcsb pdb:6TQS|rcsb pdb:6TQT|rcsb pdb:6TQU|reactome:R-HSA-6798695|reactome:R-HSA-9013405|ensembl:ENSG00000130150(gene)|ensembl:ENST00000380492(transcript)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006935"(chemotaxis)|go:"GO:0016020"(membrane)|go:"GO:0035579"(specific granule membrane)|go:"GO:0044232"(organelle membrane contact site) uniprotkb:F5GYQ2(uniprot-removed-ac) - - no-uniprot-update:|caution:The sequence has been withdrawn from uniprot. figure legend:Fig. 5A, Supp. Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells) - 2020/05/21 2021/04/12 rogid:WEdwMYKpu1uQll5NXnMm4P51R4E9606 rogid:D5nknVQzGJHCDwtvFu2FtowmY+o9606 rigid:1P63pNv1yn3F27gcT2OsGH/3EDQ false green fluorescent protein tag:n-n|mutation disrupting interaction strength:406-406,404-404 - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q8NHP6 uniprotkb:I3L0K7 intact:EBI-2812848|uniprotkb:Q8NA83|uniprotkb:Q8N3H2|ensembl:ENSP00000369860 intact:EBI-25617984|ensembl:ENSP00000458166 psi-mi:mspd2_human(display_long)|uniprotkb:MOSPD2(gene name)|psi-mi:MOSPD2(display_short) psi-mi:i3l0k7_human(display_long)|uniprotkb:TRAP1(gene name)|psi-mi:TRAP1(display_short)|uniprotkb:hCG_16634(orf name) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Di et al. (2018) pubmed:29858488|imex:IM-28178 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-25617558|imex:IM-28178-11 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001170946.1|refseq:NP_689794.1|go:"GO:0090023"(positive regulation of neutrophil chemotaxis)|go:"GO:0090026"(positive regulation of monocyte chemotaxis)|go:"GO:0140284"(endoplasmic reticulum-endosome membrane contact site)|interpro:IPR000535(Major sperm protein)|interpro:IPR001251(Cellular retinaldehyde-binding/triple function, C-terminal)|interpro:IPR008962(PapD-like)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR036273|interpro:IPR036865|mint:Q8NHP6|rcsb pdb:6TQS|rcsb pdb:6TQT|rcsb pdb:6TQU|reactome:R-HSA-6798695|reactome:R-HSA-9013405|ensembl:ENSG00000130150(gene)|ensembl:ENST00000380492(transcript)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006935"(chemotaxis)|go:"GO:0016020"(membrane)|go:"GO:0035579"(specific granule membrane)|go:"GO:0044232"(organelle membrane contact site) ensembl:ENSG00000126602(gene)|ensembl:ENST00000575671(transcript)|go:"GO:0005524"(ATP binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0006457"(protein folding)|go:"GO:0051082"(unfolded protein binding)|interpro:IPR001404(Heat shock protein Hsp90)|interpro:IPR020568|interpro:IPR020575|interpro:IPR036890|interpro:IPR037196 - - - figure legend:Fig. 5A, Supp. Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells) - 2020/05/21 2021/04/12 rogid:WEdwMYKpu1uQll5NXnMm4P51R4E9606 rogid:m4ShaYjCVark3A95RTz8SlC76/A9606 rigid:1P63pNv1yn3F27gcT2OsGH/3EDQ false green fluorescent protein tag:n-n|mutation disrupting interaction strength:406-406,404-404 - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q8NHP6 uniprotkb:P55072 intact:EBI-2812848|uniprotkb:Q8NA83|uniprotkb:Q8N3H2|ensembl:ENSP00000369860 intact:EBI-355164|uniprotkb:Q969G7|uniprotkb:Q9UCD5|uniprotkb:B2R5T8|uniprotkb:Q0V924|uniprotkb:Q2TAI5|intact:EBI-1046421|ensembl:ENSP00000351777 psi-mi:mspd2_human(display_long)|uniprotkb:MOSPD2(gene name)|psi-mi:MOSPD2(display_short) psi-mi:tera_human(display_long)|uniprotkb:VCP(gene name)|psi-mi:VCP(display_short)|uniprotkb:"15S Mg(2+)-ATPase p97 subunit"(gene name synonym)|uniprotkb:Valosin-containing protein(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Di et al. (2018) pubmed:29858488|imex:IM-28178 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-25617558|imex:IM-28178-11 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001170946.1|refseq:NP_689794.1|go:"GO:0090023"(positive regulation of neutrophil chemotaxis)|go:"GO:0090026"(positive regulation of monocyte chemotaxis)|go:"GO:0140284"(endoplasmic reticulum-endosome membrane contact site)|interpro:IPR000535(Major sperm protein)|interpro:IPR001251(Cellular retinaldehyde-binding/triple function, C-terminal)|interpro:IPR008962(PapD-like)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR036273|interpro:IPR036865|mint:Q8NHP6|rcsb pdb:6TQS|rcsb pdb:6TQT|rcsb pdb:6TQU|reactome:R-HSA-6798695|reactome:R-HSA-9013405|ensembl:ENSG00000130150(gene)|ensembl:ENST00000380492(transcript)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006935"(chemotaxis)|go:"GO:0016020"(membrane)|go:"GO:0035579"(specific granule membrane)|go:"GO:0044232"(organelle membrane contact site) refseq:NP_009057.1|rcsb pdb:7BPA|rcsb pdb:7BPB|rcsb pdb:7JY5|reactome:R-HSA-110320|reactome:R-HSA-3371511|reactome:R-HSA-382556|reactome:R-HSA-532668|reactome:R-HSA-5358346|reactome:R-HSA-5362768|reactome:R-HSA-5678895|reactome:R-HSA-5689877|reactome:R-HSA-5689896|reactome:R-HSA-6798695|reactome:R-HSA-8866654|reactome:R-HSA-8876725|reactome:R-HSA-9013407|reactome:R-HSA-9646399|reactome:R-HSA-9678110|reactome:R-HSA-9694614|rcsb pdb:7BP9|go:"GO:0032510"(endosome to lysosome transport via multivesicular body sorting pathway)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034098"(VCP-NPL4-UFD1 AAA ATPase complex)|go:"GO:0034605"(cellular response to heat)|go:"GO:0034774"(secretory granule lumen)|go:"GO:0035578"(azurophil granule lumen)|go:"GO:0035617"(stress granule disassembly)|go:"GO:0035800"(deubiquitinase activator activity)|go:"GO:0035861"(site of double-strand break)|go:"GO:0036297"(interstrand cross-link repair)|go:"GO:0036435"(K48-linked polyubiquitin modification-dependent protein binding)|go:"GO:0036503"(ERAD pathway)|go:"GO:0036513"(Derlin-1 retrotranslocation complex)|go:"GO:0042288"(MHC class I protein binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0032436"(positive regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0043531"(ADP binding)|go:"GO:0044389"(ubiquitin-like protein ligase binding)|go:"GO:0045184"(establishment of protein localization)|go:"GO:0045732"(positive regulation of protein catabolic process)|go:"GO:0045879"(negative regulation of smoothened signaling pathway)|go:"GO:0046034"(ATP metabolic process)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0050807"(regulation of synapse organization)|go:"GO:0051228"(mitotic spindle disassembly)|go:"GO:0061857"(endoplasmic reticulum stress-induced pre-emptive quality control)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070842"(aggresome assembly)|go:"GO:0071712"(ER-associated misfolded protein catabolic process)|go:"GO:0072389"(flavin adenine dinucleotide catabolic process)|go:"GO:0090263"(positive regulation of canonical Wnt signaling pathway)|go:"GO:0097352"(autophagosome maturation)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0106300"(protein-DNA covalent cross-linking repair)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|go:"GO:1903006"(positive regulation of protein K63-linked deubiquitination)|go:"GO:1903007"(positive regulation of Lys63-specific deubiquitinase activity)|go:"GO:1903715"(regulation of aerobic respiration)|go:"GO:1903843"(cellular response to arsenite ion)|go:"GO:1903862"(positive regulation of oxidative phosphorylation)|go:"GO:1904288"(BAT3 complex binding)|go:"GO:1904813"(ficolin-1-rich granule lumen)|go:"GO:1904949"(ATPase complex)|go:"GO:1905634"(regulation of protein localization to chromatin)|go:"GO:1990381"(ubiquitin-specific protease binding)|go:"GO:1990730"(VCP-NSFL1C complex)|go:"GO:2001171"(positive regulation of ATP biosynthetic process)|interpro:IPR003338(AAA ATPase VAT, N-terminal)|interpro:IPR003593(AAA+ ATPase, core)|ensembl:ENSG00000165280(gene)|ensembl:ENST00000358901(transcript)|go:"GO:0000502"(proteasome complex)|go:"GO:0003723"(RNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005811"(lipid droplet)|go:"GO:0005829"(cytosol)|go:"GO:0006281"(DNA repair)|go:"GO:0006302"(double-strand break repair)|go:"GO:0006734"(NADH metabolic process)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0006914"(autophagy)|go:"GO:0006919"(activation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0008289"(lipid binding)|go:"GO:0010494"(cytoplasmic stress granule)|go:"GO:0010498"(proteasomal protein catabolic process)|go:"GO:0010918"(positive regulation of mitochondrial membrane potential)|go:"GO:0016236"(macroautophagy)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0019079"(viral genome replication)|go:"GO:0019903"(protein phosphatase binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0019985"(translesion synthesis)|go:"GO:0030433"(ubiquitin-dependent ERAD pathway)|go:"GO:0030968"(endoplasmic reticulum unfolded protein response)|go:"GO:0030970"(retrograde protein transport, ER to cytosol)|go:"GO:0031334"(positive regulation of protein-containing complex assembly)|go:"GO:0031593"(polyubiquitin modification-dependent protein binding)|go:"GO:0031625"(ubiquitin protein ligase binding)|interpro:IPR003959(AAA ATPase, core)|interpro:IPR003960(AAA ATPase, conserved site)|interpro:IPR004201(Cell division protein 48, CDC48, domain 2)|interpro:IPR005938(AAA ATPase, CDC48)|interpro:IPR009010(Aspartate decarboxylase-like fold)|interpro:IPR015415(Vps4 oligomerisation, C-terminal)|interpro:IPR027417|interpro:IPR029067|interpro:IPR041569|mint:P55072|rcsb pdb:3EBB|rcsb pdb:3HU1|rcsb pdb:3HU2|rcsb pdb:3HU3|rcsb pdb:3QC8|rcsb pdb:3QQ7|rcsb pdb:3QQ8|rcsb pdb:3QWZ|rcsb pdb:3TIW|rcsb pdb:4KDI|rcsb pdb:4KDL|rcsb pdb:4KLN|rcsb pdb:4KO8|rcsb pdb:4KOD|rcsb pdb:4P0A|rcsb pdb:5B6C|rcsb pdb:5C18|rcsb pdb:5C19|rcsb pdb:5C1A|rcsb pdb:5C1B|rcsb pdb:5DYG|rcsb pdb:5DYI|rcsb pdb:5EPP|rcsb pdb:5FTJ|rcsb pdb:5FTK|rcsb pdb:5FTL|rcsb pdb:5FTM|rcsb pdb:5FTN|rcsb pdb:5GLF|rcsb pdb:5IFS|rcsb pdb:5IFW|rcsb pdb:5KIW|rcsb pdb:5KIY|rcsb pdb:5X4L|rcsb pdb:6G2V|rcsb pdb:6G2W|rcsb pdb:6G2X|rcsb pdb:6G2Y|rcsb pdb:6G2Z|rcsb pdb:6G30|rcsb pdb:6HD0|rcsb pdb:6MCK|rcsb pdb:7BP8|dip:DIP-33543N - - - figure legend:Fig. 5A, Supp. Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells) - 2020/05/21 2021/04/12 rogid:WEdwMYKpu1uQll5NXnMm4P51R4E9606 rogid:HrjDhdsDcgaf8HEbqqMjUqxPaEs9606 rigid:1P63pNv1yn3F27gcT2OsGH/3EDQ false green fluorescent protein tag:n-n|mutation disrupting interaction strength:406-406,404-404 - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q8NHP6 uniprotkb:Q13283 intact:EBI-2812848|uniprotkb:Q8NA83|uniprotkb:Q8N3H2|ensembl:ENSP00000369860 intact:EBI-1047359|intact:EBI-1384154|ensembl:ENSP00000348578|ensembl:ENSP00000377681|ensembl:ENSP00000430480|ensembl:ENSP00000502880|ensembl:ENSP00000503039|ensembl:ENSP00000503699|ensembl:ENSP00000503939|ensembl:ENSP00000504140|ensembl:ENSP00000504627|uniprotkb:Q5HYE9 psi-mi:mspd2_human(display_long)|uniprotkb:MOSPD2(gene name)|psi-mi:MOSPD2(display_short) psi-mi:g3bp1_human(display_long)|uniprotkb:G3BP1(gene name)|psi-mi:G3BP1(display_short)|uniprotkb:G3BP(gene name synonym)|uniprotkb:ATP-dependent DNA helicase VIII(gene name synonym)|uniprotkb:GAP SH3 domain-binding protein 1(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Di et al. (2018) pubmed:29858488|imex:IM-28178 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-25617558|imex:IM-28178-11 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001170946.1|refseq:NP_689794.1|go:"GO:0090023"(positive regulation of neutrophil chemotaxis)|go:"GO:0090026"(positive regulation of monocyte chemotaxis)|go:"GO:0140284"(endoplasmic reticulum-endosome membrane contact site)|interpro:IPR000535(Major sperm protein)|interpro:IPR001251(Cellular retinaldehyde-binding/triple function, C-terminal)|interpro:IPR008962(PapD-like)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR036273|interpro:IPR036865|mint:Q8NHP6|rcsb pdb:6TQS|rcsb pdb:6TQT|rcsb pdb:6TQU|reactome:R-HSA-6798695|reactome:R-HSA-9013405|ensembl:ENSG00000130150(gene)|ensembl:ENST00000380492(transcript)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006935"(chemotaxis)|go:"GO:0016020"(membrane)|go:"GO:0035579"(specific granule membrane)|go:"GO:0044232"(organelle membrane contact site) refseq:NP_005745.1|refseq:NP_938405.1|ensembl:ENSG00000145907(gene)|go:"GO:0003729"(mRNA binding)|go:"GO:0004519"(endonuclease activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005925"(focal adhesion)|go:"GO:0007265"(Ras protein signal transduction)|go:"GO:0010494"(cytoplasmic stress granule)|go:"GO:0032481"(positive regulation of type I interferon production)|go:"GO:0033677"(DNA/RNA helicase activity)|go:"GO:0034063"(stress granule assembly)|go:"GO:0043204"(perikaryon)|go:"GO:0045087"(innate immune response)|go:"GO:0051607"(defense response to virus)|go:"GO:0062029"(positive regulation of stress granule assembly)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR002075(Nuclear transport factor 2)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR018222|interpro:IPR032710|interpro:IPR034374|interpro:IPR034375|interpro:IPR035979|interpro:IPR039539|mint:Q13283|ensembl:ENST00000356245(transcript)|rcsb pdb:3Q90|rcsb pdb:4FCJ|rcsb pdb:4FCM|rcsb pdb:4IIA|rcsb pdb:5FW5|rcsb pdb:6TA7|ensembl:ENST00000394123(transcript)|ensembl:ENST00000522761(transcript)|ensembl:ENST00000676827(transcript)|ensembl:ENST00000676978(transcript)|ensembl:ENST00000677323(transcript)|ensembl:ENST00000678070(transcript)|ensembl:ENST00000678101(transcript)|ensembl:ENST00000678925(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0003678"(DNA helicase activity)|go:"GO:0003723"(RNA binding)|go:"GO:0003724"(RNA helicase activity)|refseq:XP_006714812.1|refseq:XP_006714813.1|refseq:XP_016864411.1|refseq:XP_016864412.1 - - - figure legend:Fig. 5A, Supp. Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells) - 2020/05/21 2021/04/12 rogid:WEdwMYKpu1uQll5NXnMm4P51R4E9606 rogid:0ZRCHNVEmmtGEOASNwg3kIm2uys9606 rigid:1P63pNv1yn3F27gcT2OsGH/3EDQ false green fluorescent protein tag:n-n|mutation disrupting interaction strength:406-406,404-404 - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q8NHP6 uniprotkb:Q15637 intact:EBI-2812848|uniprotkb:Q8NA83|uniprotkb:Q8N3H2|ensembl:ENSP00000369860 intact:EBI-744603|uniprotkb:Q14818|uniprotkb:Q14819|uniprotkb:Q15913|uniprotkb:Q8IY00|uniprotkb:Q92744|uniprotkb:Q92745|uniprotkb:Q969H7|uniprotkb:Q9BW01|uniprotkb:Q9UEI0|uniprotkb:B7Z1Q1|uniprotkb:C9JJE2|ensembl:ENSP00000366607 psi-mi:mspd2_human(display_long)|uniprotkb:MOSPD2(gene name)|psi-mi:MOSPD2(display_short) psi-mi:sf01_human(display_long)|uniprotkb:Zinc finger protein 162(gene name synonym)|uniprotkb:Transcription factor ZFM1(gene name synonym)|uniprotkb:Zinc finger gene in MEN1 locus(gene name synonym)|uniprotkb:Mammalian branch point-binding protein(gene name synonym)|uniprotkb:SF1(gene name)|psi-mi:SF1(display_short)|uniprotkb:ZFM1(gene name synonym)|uniprotkb:ZNF162(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Di et al. (2018) pubmed:29858488|imex:IM-28178 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-25617558|imex:IM-28178-11 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001170946.1|refseq:NP_689794.1|go:"GO:0090023"(positive regulation of neutrophil chemotaxis)|go:"GO:0090026"(positive regulation of monocyte chemotaxis)|go:"GO:0140284"(endoplasmic reticulum-endosome membrane contact site)|interpro:IPR000535(Major sperm protein)|interpro:IPR001251(Cellular retinaldehyde-binding/triple function, C-terminal)|interpro:IPR008962(PapD-like)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR036273|interpro:IPR036865|mint:Q8NHP6|rcsb pdb:6TQS|rcsb pdb:6TQT|rcsb pdb:6TQU|reactome:R-HSA-6798695|reactome:R-HSA-9013405|ensembl:ENSG00000130150(gene)|ensembl:ENST00000380492(transcript)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006935"(chemotaxis)|go:"GO:0016020"(membrane)|go:"GO:0035579"(specific granule membrane)|go:"GO:0044232"(organelle membrane contact site) refseq:NP_001171501.1|refseq:NP_001171502.1|refseq:NP_004621.2|refseq:NP_973724.1|refseq:NP_973727.1|rcsb pdb:4FXX|rcsb pdb:4FXW|reactome:R-HSA-72163|refseq:XP_016873733.1|ensembl:ENSG00000168066(gene)|ensembl:ENST00000377390(transcript)|go:"GO:0000245"(spliceosomal complex assembly)|go:"GO:0000389"(mRNA 3'-splice site recognition)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005681"(spliceosomal complex)|go:"GO:0005840"(ribosome)|go:"GO:0008270"(zinc ion binding)|go:"GO:0016604"(nuclear body)|go:"GO:0030238"(male sex determination)|go:"GO:0030575"(nuclear body organization)|go:"GO:0033327"(Leydig cell differentiation)|go:"GO:0042802"(identical protein binding)|go:"GO:0045131"(pre-mRNA branch point binding)|go:"GO:0048024"(regulation of mRNA splicing, via spliceosome)|go:"GO:0048662"(negative regulation of smooth muscle cell proliferation)|go:"GO:0050810"(regulation of steroid biosynthetic process)|interpro:IPR001878(Zinc finger, CCHC-type)|interpro:IPR004087(K Homology)|interpro:IPR004088(K Homology, type 1)|interpro:IPR031150|interpro:IPR032570|interpro:IPR036612|mint:Q15637|rcsb pdb:1K1G|rcsb pdb:1O0P|rcsb pdb:1OPI|rcsb pdb:2M09|rcsb pdb:2M0G|refseq:NP_001333292.1|refseq:NP_001333293.1|dip:DIP-29410N - - - figure legend:Fig. 5A, Supp. Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells) - 2020/05/21 2021/04/12 rogid:WEdwMYKpu1uQll5NXnMm4P51R4E9606 rogid:N4k5Rvc5EDsSJt50J4ojje9p0249606 rigid:1P63pNv1yn3F27gcT2OsGH/3EDQ false green fluorescent protein tag:n-n|mutation disrupting interaction strength:406-406,404-404 - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q8NHP6 uniprotkb:P0CW18 intact:EBI-2812848|uniprotkb:Q8NA83|uniprotkb:Q8N3H2|ensembl:ENSP00000369860 intact:EBI-11068403|ensembl:ENSP00000479745 psi-mi:mspd2_human(display_long)|uniprotkb:MOSPD2(gene name)|psi-mi:MOSPD2(display_short) psi-mi:prs56_human(display_long)|uniprotkb:PRSS56(gene name)|psi-mi:PRSS56(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Di et al. (2018) pubmed:29858488|imex:IM-28178 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-25617558|imex:IM-28178-11 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001170946.1|refseq:NP_689794.1|go:"GO:0090023"(positive regulation of neutrophil chemotaxis)|go:"GO:0090026"(positive regulation of monocyte chemotaxis)|go:"GO:0140284"(endoplasmic reticulum-endosome membrane contact site)|interpro:IPR000535(Major sperm protein)|interpro:IPR001251(Cellular retinaldehyde-binding/triple function, C-terminal)|interpro:IPR008962(PapD-like)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR036273|interpro:IPR036865|mint:Q8NHP6|rcsb pdb:6TQS|rcsb pdb:6TQT|rcsb pdb:6TQU|reactome:R-HSA-6798695|reactome:R-HSA-9013405|ensembl:ENSG00000130150(gene)|ensembl:ENST00000380492(transcript)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006935"(chemotaxis)|go:"GO:0016020"(membrane)|go:"GO:0035579"(specific granule membrane)|go:"GO:0044232"(organelle membrane contact site) refseq:NP_001182058.1|ensembl:ENSG00000237412(gene)|ensembl:ENST00000617714(transcript)|go:"GO:0002690"(positive regulation of leukocyte chemotaxis)|go:"GO:0004252"(serine-type endopeptidase activity)|go:"GO:0005615"(extracellular space)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0006508"(proteolysis)|go:"GO:0007596"(blood coagulation)|go:"GO:0043010"(camera-type eye development)|interpro:IPR001254(Peptidase S1 and S6, chymotrypsin/Hap)|interpro:IPR001314(Peptidase S1A, chymotrypsin)|interpro:IPR009003(Peptidase, trypsin-like serine and cysteine)|interpro:IPR018114|interpro:IPR033116|interpro:IPR043504 - - - figure legend:Fig. 5A, Supp. Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells) - 2020/05/21 2021/04/12 rogid:WEdwMYKpu1uQll5NXnMm4P51R4E9606 rogid:+yDVI9IGYvS8GG0fOvhhYqoAIYQ9606 rigid:1P63pNv1yn3F27gcT2OsGH/3EDQ false green fluorescent protein tag:n-n|mutation disrupting interaction strength:406-406,404-404 - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q8NHP6 uniprotkb:Q15526 intact:EBI-2812848|uniprotkb:Q8NA83|uniprotkb:Q8N3H2|ensembl:ENSP00000369860 intact:EBI-3915286|uniprotkb:Q5T8T3|uniprotkb:Q5T8T4|ensembl:ENSP00000361042|ensembl:ENSP00000487158 psi-mi:mspd2_human(display_long)|uniprotkb:MOSPD2(gene name)|psi-mi:MOSPD2(display_short) psi-mi:surf1_human(display_long)|uniprotkb:SURF1(gene name)|psi-mi:SURF1(display_short)|uniprotkb:SURF-1(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Di et al. (2018) pubmed:29858488|imex:IM-28178 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-25617558|imex:IM-28178-11 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001170946.1|refseq:NP_689794.1|go:"GO:0090023"(positive regulation of neutrophil chemotaxis)|go:"GO:0090026"(positive regulation of monocyte chemotaxis)|go:"GO:0140284"(endoplasmic reticulum-endosome membrane contact site)|interpro:IPR000535(Major sperm protein)|interpro:IPR001251(Cellular retinaldehyde-binding/triple function, C-terminal)|interpro:IPR008962(PapD-like)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR036273|interpro:IPR036865|mint:Q8NHP6|rcsb pdb:6TQS|rcsb pdb:6TQT|rcsb pdb:6TQU|reactome:R-HSA-6798695|reactome:R-HSA-9013405|ensembl:ENSG00000130150(gene)|ensembl:ENST00000380492(transcript)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006935"(chemotaxis)|go:"GO:0016020"(membrane)|go:"GO:0035579"(specific granule membrane)|go:"GO:0044232"(organelle membrane contact site) refseq:NP_003163.1|refseq:NP_001267716.1|ensembl:ENSG00000148290(gene)|ensembl:ENSG00000280627(gene)|ensembl:ENST00000371974(transcript)|ensembl:ENST00000626663(transcript)|go:"GO:0004129"(cytochrome-c oxidase activity)|go:"GO:0005746"(mitochondrial respirasome)|go:"GO:0008535"(respiratory chain complex IV assembly)|go:"GO:0009060"(aerobic respiration)|go:"GO:0016021"(integral component of membrane)|go:"GO:0033617"(mitochondrial cytochrome c oxidase assembly)|interpro:IPR002994(Surfeit locus 1)|reactome:R-HSA-5628897|reactome:R-HSA-611105|reactome:R-HSA-9707564 - - - figure legend:Fig. 5A, Supp. Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells) - 2020/05/21 2021/04/12 rogid:WEdwMYKpu1uQll5NXnMm4P51R4E9606 rogid:HGpXJhbeMdDuz7amqIgWqxlHicA9606 rigid:1P63pNv1yn3F27gcT2OsGH/3EDQ false green fluorescent protein tag:n-n|mutation disrupting interaction strength:406-406,404-404 - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q8NHP6 uniprotkb:Q07666 intact:EBI-2812848|uniprotkb:Q8NA83|uniprotkb:Q8N3H2|ensembl:ENSP00000369860 intact:EBI-1364|uniprotkb:Q6PJX7|uniprotkb:Q8NB97|uniprotkb:Q99760|uniprotkb:D3DPP3|ensembl:ENSP00000313829 psi-mi:mspd2_human(display_long)|uniprotkb:MOSPD2(gene name)|psi-mi:MOSPD2(display_short) psi-mi:khdr1_human(display_long)|uniprotkb:SAM68(gene name synonym)|uniprotkb:Src-associated in mitosis 68 kDa protein(gene name synonym)|uniprotkb:KHDRBS1(gene name)|psi-mi:KHDRBS1(display_short)|uniprotkb:p21 Ras GTPase-activating protein-associated p62(gene name synonym)|uniprotkb:GAP-associated tyrosine phosphoprotein p62(gene name synonym)|uniprotkb:p68(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Di et al. (2018) pubmed:29858488|imex:IM-28178 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-25617558|imex:IM-28178-11 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001170946.1|refseq:NP_689794.1|go:"GO:0090023"(positive regulation of neutrophil chemotaxis)|go:"GO:0090026"(positive regulation of monocyte chemotaxis)|go:"GO:0140284"(endoplasmic reticulum-endosome membrane contact site)|interpro:IPR000535(Major sperm protein)|interpro:IPR001251(Cellular retinaldehyde-binding/triple function, C-terminal)|interpro:IPR008962(PapD-like)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR036273|interpro:IPR036865|mint:Q8NHP6|rcsb pdb:6TQS|rcsb pdb:6TQT|rcsb pdb:6TQU|reactome:R-HSA-6798695|reactome:R-HSA-9013405|ensembl:ENSG00000130150(gene)|ensembl:ENST00000380492(transcript)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006935"(chemotaxis)|go:"GO:0016020"(membrane)|go:"GO:0035579"(specific granule membrane)|go:"GO:0044232"(organelle membrane contact site) refseq:NP_006550.1|refseq:NP_001258807.1|dip:DIP-29007N|ensembl:ENSG00000121774(gene)|ensembl:ENST00000327300(transcript)|go:"GO:0000082"(G1/S transition of mitotic cell cycle)|go:"GO:0000086"(G2/M transition of mitotic cell cycle)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000381"(regulation of alternative mRNA splicing, via spliceosome)|go:"GO:0003677"(DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006397"(mRNA processing)|go:"GO:0007283"(spermatogenesis)|go:"GO:0008143"("poly(A) binding")|go:"GO:0008266"("poly(U) RNA binding")|go:"GO:0016020"(membrane)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035591"(signaling adaptor activity)|go:"GO:0042169"(SH2 domain binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045948"(positive regulation of translational initiation)|go:"GO:0046831"(regulation of RNA export from nucleus)|go:"GO:0046833"(positive regulation of RNA export from nucleus)|go:"GO:0048024"(regulation of mRNA splicing, via spliceosome)|go:"GO:0050852"(T cell receptor signaling pathway)|go:"GO:0070618"(Grb2-Sos complex)|go:"GO:1990782"(protein tyrosine kinase binding)|interpro:IPR004087(K Homology)|interpro:IPR004088(K Homology, type 1)|interpro:IPR032335|interpro:IPR032571|interpro:IPR036612|mint:Q07666|rcsb pdb:2XA6|rcsb pdb:3QHE|reactome:R-HSA-8849468 - - - figure legend:Fig. 5A, Supp. Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells) - 2020/05/21 2021/04/12 rogid:WEdwMYKpu1uQll5NXnMm4P51R4E9606 rogid:po7jC4Nxu+Aoz6T8K6VRWHp6MKQ9606 rigid:1P63pNv1yn3F27gcT2OsGH/3EDQ false green fluorescent protein tag:n-n|mutation disrupting interaction strength:406-406,404-404 - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q8NHP6 uniprotkb:P51570 intact:EBI-2812848|uniprotkb:Q8NA83|uniprotkb:Q8N3H2|ensembl:ENSP00000369860 intact:EBI-2269932|uniprotkb:B2RC07|intact:EBI-6190170|uniprotkb:B4E1G6|ensembl:ENSP00000225614|ensembl:ENSP00000465930 psi-mi:mspd2_human(display_long)|uniprotkb:MOSPD2(gene name)|psi-mi:MOSPD2(display_short) psi-mi:galk1_human(display_long)|uniprotkb:GALK1(gene name)|psi-mi:GALK1(display_short)|uniprotkb:GALK(gene name synonym)|uniprotkb:Galactose kinase(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Di et al. (2018) pubmed:29858488|imex:IM-28178 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-25617558|imex:IM-28178-11 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001170946.1|refseq:NP_689794.1|go:"GO:0090023"(positive regulation of neutrophil chemotaxis)|go:"GO:0090026"(positive regulation of monocyte chemotaxis)|go:"GO:0140284"(endoplasmic reticulum-endosome membrane contact site)|interpro:IPR000535(Major sperm protein)|interpro:IPR001251(Cellular retinaldehyde-binding/triple function, C-terminal)|interpro:IPR008962(PapD-like)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR036273|interpro:IPR036865|mint:Q8NHP6|rcsb pdb:6TQS|rcsb pdb:6TQT|rcsb pdb:6TQU|reactome:R-HSA-6798695|reactome:R-HSA-9013405|ensembl:ENSG00000130150(gene)|ensembl:ENST00000380492(transcript)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006935"(chemotaxis)|go:"GO:0016020"(membrane)|go:"GO:0035579"(specific granule membrane)|go:"GO:0044232"(organelle membrane contact site) go:"GO:0019388"(galactose catabolic process)|go:"GO:0019402"(galactitol metabolic process)|go:"GO:0061623"(glycolytic process from galactose)|go:"GO:0070062"(extracellular exosome)|interpro:IPR000705(Galactokinase)|interpro:IPR006203(GHMP kinase, ATP-binding, conserved site)|interpro:IPR006204(GHMP kinase)|interpro:IPR006206(Mevalonate and galactokinase)|interpro:IPR013750(GHMP kinase, C-terminal)|interpro:IPR014721(Ribosomal protein S5 domain 2-type fold)|interpro:IPR019539|interpro:IPR019741|interpro:IPR020568|interpro:IPR036554|mint:P51570|ensembl:ENSG00000108479(gene)|ensembl:ENST00000225614(transcript)|ensembl:ENST00000588479(transcript)|go:"GO:0004335"(galactokinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005534"(galactose binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006012"(galactose metabolic process)|go:"GO:0016020"(membrane)|rcsb pdb:1WUU|rcsb pdb:1YH7|rcsb pdb:6GR2|rcsb pdb:6Q3W|rcsb pdb:6Q3X|rcsb pdb:6Q8Z|rcsb pdb:6Q90|rcsb pdb:6Q91|rcsb pdb:6QJE|rcsb pdb:6ZFH|rcsb pdb:6ZGV|rcsb pdb:6ZGW|rcsb pdb:6ZGX|rcsb pdb:6ZGY|rcsb pdb:6ZGZ|reactome:R-HSA-5609976|reactome:R-HSA-70370 - - - figure legend:Fig. 5A, Supp. Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells) - 2020/05/21 2021/04/12 rogid:WEdwMYKpu1uQll5NXnMm4P51R4E9606 rogid:TtFcTQq+nspsst+xInA/huo/ZbU9606 rigid:1P63pNv1yn3F27gcT2OsGH/3EDQ false green fluorescent protein tag:n-n|mutation disrupting interaction strength:406-406,404-404 - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q8NHP6 uniprotkb:Q9UJS0 intact:EBI-2812848|uniprotkb:Q8NA83|uniprotkb:Q8N3H2|ensembl:ENSP00000369860 intact:EBI-1222503|uniprotkb:O14566|uniprotkb:O14575|uniprotkb:Q9NZW1|uniprotkb:Q9UNI7|uniprotkb:Q546F9|ensembl:ENSP00000265631 psi-mi:mspd2_human(display_long)|uniprotkb:MOSPD2(gene name)|psi-mi:MOSPD2(display_short) psi-mi:cmc2_human(display_long)|uniprotkb:SLC25A13(gene name)|psi-mi:SLC25A13(display_short)|uniprotkb:ARALAR2(gene name synonym)|uniprotkb:Mitochondrial aspartate glutamate carrier 2(gene name synonym)|uniprotkb:Solute carrier family 25 member 13(gene name synonym)|uniprotkb:Citrin(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Di et al. (2018) pubmed:29858488|imex:IM-28178 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-25617558|imex:IM-28178-11 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001170946.1|refseq:NP_689794.1|go:"GO:0090023"(positive regulation of neutrophil chemotaxis)|go:"GO:0090026"(positive regulation of monocyte chemotaxis)|go:"GO:0140284"(endoplasmic reticulum-endosome membrane contact site)|interpro:IPR000535(Major sperm protein)|interpro:IPR001251(Cellular retinaldehyde-binding/triple function, C-terminal)|interpro:IPR008962(PapD-like)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR036273|interpro:IPR036865|mint:Q8NHP6|rcsb pdb:6TQS|rcsb pdb:6TQT|rcsb pdb:6TQU|reactome:R-HSA-6798695|reactome:R-HSA-9013405|ensembl:ENSG00000130150(gene)|ensembl:ENST00000380492(transcript)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006935"(chemotaxis)|go:"GO:0016020"(membrane)|go:"GO:0035579"(specific granule membrane)|go:"GO:0044232"(organelle membrane contact site) refseq:NP_055066.1|refseq:NP_001153682.1|go:"GO:0005313"(L-glutamate transmembrane transporter activity)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006094"(gluconeogenesis)|go:"GO:0006754"(ATP biosynthetic process)|go:"GO:0006839"(mitochondrial transport)|go:"GO:0009066"(aspartate family amino acid metabolic process)|go:"GO:0015172"(acidic amino acid transmembrane transporter activity)|go:"GO:0015183"(L-aspartate transmembrane transporter activity)|go:"GO:0015810"(aspartate transmembrane transport)|go:"GO:0015813"(L-glutamate transmembrane transport)|go:"GO:0022857"(transmembrane transporter activity)|go:"GO:0042802"(identical protein binding)|go:"GO:0043490"(malate-aspartate shuttle)|go:"GO:0045333"(cellular respiration)|go:"GO:0051592"(response to calcium ion)|interpro:IPR002048(Calcium-binding EF-hand)|interpro:IPR002067(Mitochondrial carrier protein)|interpro:IPR011992(EF-Hand type)|interpro:IPR018108|interpro:IPR023395|interpro:IPR029658|mint:Q9UJS0|rcsb pdb:4P5W|reactome:R-HSA-1268020|reactome:R-HSA-70263|reactome:R-HSA-8963693|ensembl:ENSG00000004864(gene)|ensembl:ENST00000265631(transcript) - - - figure legend:Fig. 5A, Supp. Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells) - 2020/05/21 2021/04/12 rogid:WEdwMYKpu1uQll5NXnMm4P51R4E9606 rogid:YtrKzkRujsJ/hzl2bJaLgJAAswI9606 rigid:1P63pNv1yn3F27gcT2OsGH/3EDQ false green fluorescent protein tag:n-n|mutation disrupting interaction strength:406-406,404-404 - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q8NHP6 uniprotkb:J3KTA4 intact:EBI-2812848|uniprotkb:Q8NA83|uniprotkb:Q8N3H2|ensembl:ENSP00000369860 intact:EBI-21359408|ensembl:ENSP00000462885 psi-mi:mspd2_human(display_long)|uniprotkb:MOSPD2(gene name)|psi-mi:MOSPD2(display_short) psi-mi:j3kta4_human(display_long)|uniprotkb:DDX5(gene name)|psi-mi:DDX5(display_short)|uniprotkb:Probable ATP-dependent RNA helicase DDX5(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Di et al. (2018) pubmed:29858488|imex:IM-28178 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-25617558|imex:IM-28178-11 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001170946.1|refseq:NP_689794.1|go:"GO:0090023"(positive regulation of neutrophil chemotaxis)|go:"GO:0090026"(positive regulation of monocyte chemotaxis)|go:"GO:0140284"(endoplasmic reticulum-endosome membrane contact site)|interpro:IPR000535(Major sperm protein)|interpro:IPR001251(Cellular retinaldehyde-binding/triple function, C-terminal)|interpro:IPR008962(PapD-like)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR036273|interpro:IPR036865|mint:Q8NHP6|rcsb pdb:6TQS|rcsb pdb:6TQT|rcsb pdb:6TQU|reactome:R-HSA-6798695|reactome:R-HSA-9013405|ensembl:ENSG00000130150(gene)|ensembl:ENST00000380492(transcript)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006935"(chemotaxis)|go:"GO:0016020"(membrane)|go:"GO:0035579"(specific granule membrane)|go:"GO:0044232"(organelle membrane contact site) ensembl:ENSG00000108654(gene)|ensembl:ENST00000578804(transcript)|go:"GO:0003676"(nucleic acid binding)|go:"GO:0003724"(RNA helicase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005681"(spliceosomal complex)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0048511"(rhythmic process)|interpro:IPR000629(RNA helicase, ATP-dependent, DEAD-box, conserved site)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR011545(DNA/RNA helicase, DEAD/DEAH box type, N-terminal)|interpro:IPR012587(P68HR)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR014014(RNA helicase, DEAD-box type, Q motif)|interpro:IPR027417|go:"GO:0140603"(obsolete ATP hydrolysis activity)|refseq:NP_001307526.1 - - - figure legend:Fig. 5A, Supp. Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells) - 2020/05/21 2021/04/12 rogid:WEdwMYKpu1uQll5NXnMm4P51R4E9606 rogid:3WQZTzoJ+tGsIUs8m+5gywxMQ8o9606 rigid:1P63pNv1yn3F27gcT2OsGH/3EDQ false green fluorescent protein tag:n-n|mutation disrupting interaction strength:406-406,404-404 - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q8NHP6 uniprotkb:A0A087WWY3 intact:EBI-2812848|uniprotkb:Q8NA83|uniprotkb:Q8N3H2|ensembl:ENSP00000369860 intact:EBI-25617964|ensembl:ENSP00000480593 psi-mi:mspd2_human(display_long)|uniprotkb:MOSPD2(gene name)|psi-mi:MOSPD2(display_short) psi-mi:a0a087wwy3_human(display_long)|uniprotkb:FLNA(gene name)|psi-mi:FLNA(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Di et al. (2018) pubmed:29858488|imex:IM-28178 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-25617558|imex:IM-28178-11 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001170946.1|refseq:NP_689794.1|go:"GO:0090023"(positive regulation of neutrophil chemotaxis)|go:"GO:0090026"(positive regulation of monocyte chemotaxis)|go:"GO:0140284"(endoplasmic reticulum-endosome membrane contact site)|interpro:IPR000535(Major sperm protein)|interpro:IPR001251(Cellular retinaldehyde-binding/triple function, C-terminal)|interpro:IPR008962(PapD-like)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR036273|interpro:IPR036865|mint:Q8NHP6|rcsb pdb:6TQS|rcsb pdb:6TQT|rcsb pdb:6TQU|reactome:R-HSA-6798695|reactome:R-HSA-9013405|ensembl:ENSG00000130150(gene)|ensembl:ENST00000380492(transcript)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006935"(chemotaxis)|go:"GO:0016020"(membrane)|go:"GO:0035579"(specific granule membrane)|go:"GO:0044232"(organelle membrane contact site) ensembl:ENSG00000196924(gene)|ensembl:ENST00000610817(transcript)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0030036"(actin cytoskeleton organization)|interpro:IPR001298(Filamin/ABP280 repeat)|interpro:IPR001589(Actinin-type, actin-binding, conserved site)|interpro:IPR001715(Calponin-like actin-binding)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR014756(Immunoglobulin E-set)|interpro:IPR017868|interpro:IPR036872|interpro:IPR044801|go:"GO:0051015"(actin filament binding) - - - figure legend:Fig. 5A, Supp. Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells) - 2020/05/21 2021/04/12 rogid:WEdwMYKpu1uQll5NXnMm4P51R4E9606 rogid:GyK36bd7/r8v2wIFKePVQ421Kek9606 rigid:1P63pNv1yn3F27gcT2OsGH/3EDQ false green fluorescent protein tag:n-n|mutation disrupting interaction strength:406-406,404-404 - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q8NHP6 uniprotkb:A0A0G2JRY5 intact:EBI-2812848|uniprotkb:Q8NA83|uniprotkb:Q8N3H2|ensembl:ENSP00000369860 intact:EBI-25617949|ensembl:ENSP00000487182 psi-mi:mspd2_human(display_long)|uniprotkb:MOSPD2(gene name)|psi-mi:MOSPD2(display_short) psi-mi:a0a0g2jry5_human(display_long)|uniprotkb:TAF4(gene name)|psi-mi:TAF4(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Di et al. (2018) pubmed:29858488|imex:IM-28178 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-25617558|imex:IM-28178-11 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001170946.1|refseq:NP_689794.1|go:"GO:0090023"(positive regulation of neutrophil chemotaxis)|go:"GO:0090026"(positive regulation of monocyte chemotaxis)|go:"GO:0140284"(endoplasmic reticulum-endosome membrane contact site)|interpro:IPR000535(Major sperm protein)|interpro:IPR001251(Cellular retinaldehyde-binding/triple function, C-terminal)|interpro:IPR008962(PapD-like)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR036273|interpro:IPR036865|mint:Q8NHP6|rcsb pdb:6TQS|rcsb pdb:6TQT|rcsb pdb:6TQU|reactome:R-HSA-6798695|reactome:R-HSA-9013405|ensembl:ENSG00000130150(gene)|ensembl:ENST00000380492(transcript)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006935"(chemotaxis)|go:"GO:0016020"(membrane)|go:"GO:0035579"(specific granule membrane)|go:"GO:0044232"(organelle membrane contact site) ensembl:ENSG00000280529(gene)|ensembl:ENST00000627770(transcript)|go:"GO:0005669"(transcription factor TFIID complex)|go:"GO:0006352"(DNA-templated transcription, initiation)|go:"GO:0046982"(protein heterodimerization activity)|interpro:IPR003894(TAFH/NHR1)|interpro:IPR007900(Transcription initiation factor TFIID component TAF4)|interpro:IPR009072(Histone-fold)|interpro:IPR037249 - - - figure legend:Fig. 5A, Supp. Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells) - 2020/05/21 2021/04/12 rogid:WEdwMYKpu1uQll5NXnMm4P51R4E9606 rogid:byghiyZ6lNQ4EbPNlJMryXnNypo9606 rigid:1P63pNv1yn3F27gcT2OsGH/3EDQ false green fluorescent protein tag:n-n|mutation disrupting interaction strength:406-406,404-404 - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q8NHP6 uniprotkb:Q8IVT2 intact:EBI-2812848|uniprotkb:Q8NA83|uniprotkb:Q8N3H2|ensembl:ENSP00000369860 intact:EBI-2555085|intact:EBI-28972337|ensembl:ENSP00000215582 psi-mi:mspd2_human(display_long)|uniprotkb:MOSPD2(gene name)|psi-mi:MOSPD2(display_short) psi-mi:misp_human(display_long)|uniprotkb:MISP(gene name)|psi-mi:MISP(display_short)|uniprotkb:C19orf21(gene name synonym)|uniprotkb:Mitotic spindle positioning protein(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Di et al. (2018) pubmed:29858488|imex:IM-28178 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-25617558|imex:IM-28178-11 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001170946.1|refseq:NP_689794.1|go:"GO:0090023"(positive regulation of neutrophil chemotaxis)|go:"GO:0090026"(positive regulation of monocyte chemotaxis)|go:"GO:0140284"(endoplasmic reticulum-endosome membrane contact site)|interpro:IPR000535(Major sperm protein)|interpro:IPR001251(Cellular retinaldehyde-binding/triple function, C-terminal)|interpro:IPR008962(PapD-like)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR036273|interpro:IPR036865|mint:Q8NHP6|rcsb pdb:6TQS|rcsb pdb:6TQT|rcsb pdb:6TQU|reactome:R-HSA-6798695|reactome:R-HSA-9013405|ensembl:ENSG00000130150(gene)|ensembl:ENST00000380492(transcript)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006935"(chemotaxis)|go:"GO:0016020"(membrane)|go:"GO:0035579"(specific granule membrane)|go:"GO:0044232"(organelle membrane contact site) refseq:NP_775752.1|ensembl:ENSP00000215582|refseq:XP_011525987.1|refseq:XP_011525988.1|ensembl:ENSG00000099812(gene)|ensembl:ENST00000215582(transcript)|go:"GO:0000132"(establishment of mitotic spindle orientation)|go:"GO:0005884"(actin filament)|go:"GO:0005886"(plasma membrane)|go:"GO:0005925"(focal adhesion)|go:"GO:0005938"(cell cortex)|go:"GO:0016477"(cell migration)|go:"GO:0031616"(spindle pole centrosome)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0051015"(actin filament binding)|go:"GO:0051301"(cell division)|go:"GO:0051640"(organelle localization)|go:"GO:0051660"(establishment of centrosome localization)|go:"GO:0090307"(mitotic spindle assembly)|go:"GO:1904776"(regulation of protein localization to cell cortex)|interpro:IPR029304|interpro:IPR042779 - - - figure legend:Fig. 5A, Supp. Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells) - 2020/05/21 2021/04/12 rogid:WEdwMYKpu1uQll5NXnMm4P51R4E9606 rogid:HJ0vL2U8LEer8c+rWNdKxkOv2g89606 rigid:1P63pNv1yn3F27gcT2OsGH/3EDQ false green fluorescent protein tag:n-n|mutation disrupting interaction strength:406-406,404-404 - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q8NHP6 uniprotkb:Q13049 intact:EBI-2812848|uniprotkb:Q8NA83|uniprotkb:Q8N3H2|ensembl:ENSP00000369860 intact:EBI-742790|ensembl:ENSP00000363095|ensembl:ENSP00000408292|uniprotkb:Q9NQP8 psi-mi:mspd2_human(display_long)|uniprotkb:MOSPD2(gene name)|psi-mi:MOSPD2(display_short) psi-mi:tri32_human(display_long)|uniprotkb:Zinc finger protein HT2A(gene name synonym)|uniprotkb:72 kDa Tat-interacting protein(gene name synonym)|uniprotkb:TRIM32(gene name)|psi-mi:TRIM32(display_short)|uniprotkb:HT2A(gene name synonym)|uniprotkb:Tripartite motif-containing protein 32(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase TRIM32(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Di et al. (2018) pubmed:29858488|imex:IM-28178 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-25617558|imex:IM-28178-11 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001170946.1|refseq:NP_689794.1|go:"GO:0090023"(positive regulation of neutrophil chemotaxis)|go:"GO:0090026"(positive regulation of monocyte chemotaxis)|go:"GO:0140284"(endoplasmic reticulum-endosome membrane contact site)|interpro:IPR000535(Major sperm protein)|interpro:IPR001251(Cellular retinaldehyde-binding/triple function, C-terminal)|interpro:IPR008962(PapD-like)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR036273|interpro:IPR036865|mint:Q8NHP6|rcsb pdb:6TQS|rcsb pdb:6TQT|rcsb pdb:6TQU|reactome:R-HSA-6798695|reactome:R-HSA-9013405|ensembl:ENSG00000130150(gene)|ensembl:ENST00000380492(transcript)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006935"(chemotaxis)|go:"GO:0016020"(membrane)|go:"GO:0035579"(specific granule membrane)|go:"GO:0044232"(organelle membrane contact site) go:"GO:0043621"(protein self-association)|go:"GO:0045087"(innate immune response)|go:"GO:0045444"(fat cell differentiation)|go:"GO:0045666"(positive regulation of neuron differentiation)|go:"GO:0045732"(positive regulation of protein catabolic process)|go:"GO:0045787"(positive regulation of cell cycle)|go:"GO:0045862"(positive regulation of proteolysis)|go:"GO:0046716"(muscle cell cellular homeostasis)|go:"GO:0048147"(negative regulation of fibroblast proliferation)|go:"GO:0050769"(positive regulation of neurogenesis)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|go:"GO:0051155"(positive regulation of striated muscle cell differentiation)|go:"GO:0061564"(axon development)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0070936"(protein K48-linked ubiquitination)|go:"GO:1902187"|go:"GO:1902230"(negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage)|go:"GO:1903265"(positive regulation of tumor necrosis factor-mediated signaling pathway)|go:"GO:1903883"(positive regulation of interleukin-17-mediated signaling pathway)|go:"GO:1903886"("positive regulation of chemokine (C-C motif) ligand 20 production")|go:"GO:2000147"(positive regulation of cell motility)|go:"GO:0043130"(ubiquitin binding)|ensembl:ENSG00000119401(gene)|ensembl:ENST00000373983(transcript)|ensembl:ENST00000450136(transcript)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0001894"(tissue homeostasis)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0003723"(RNA binding)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005863"(striated muscle myosin thick filament)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0007014"(actin ubiquitination)|go:"GO:0008270"(zinc ion binding)|go:"GO:0009411"(response to UV)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0017022"(myosin binding)|go:"GO:0030307"(positive regulation of cell growth)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0030957"(Tat protein binding)|go:"GO:0031369"(translation initiation factor binding)|go:"GO:0032897"(negative regulation of viral transcription)|go:"GO:0034612"(response to tumor necrosis factor)|go:"GO:0042802"(identical protein binding)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|interpro:IPR000315(Zinc finger, B-box)|refseq:NP_001093149.1|refseq:XP_011516700.1|refseq:NP_036342.2|refseq:XP_005251870.1|interpro:IPR001258(NHL repeat)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR011042(Six-bladed beta-propeller, TolB-like)|interpro:IPR013017(NHL repeat, subgroup)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017907|interpro:IPR027370|mint:Q13049|rcsb pdb:2CT2|rcsb pdb:5FEY|reactome:R-HSA-3134975|reactome:R-HSA-983168|refseq:XP_016869975.1 - - - figure legend:Fig. 5A, Supp. Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells) - 2020/05/21 2021/04/12 rogid:WEdwMYKpu1uQll5NXnMm4P51R4E9606 rogid:XuqprQd10kSpsuyGs+FSdzIdJ/Y9606 rigid:1P63pNv1yn3F27gcT2OsGH/3EDQ false green fluorescent protein tag:n-n|mutation disrupting interaction strength:406-406,404-404 - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q8NHP6 uniprotkb:P05141 intact:EBI-2812848|uniprotkb:Q8NA83|uniprotkb:Q8N3H2|ensembl:ENSP00000369860 intact:EBI-355133|uniprotkb:O43350|uniprotkb:B2RCV1|ensembl:ENSP00000360671 psi-mi:mspd2_human(display_long)|uniprotkb:MOSPD2(gene name)|psi-mi:MOSPD2(display_short) psi-mi:adt2_human(display_long)|uniprotkb:SLC25A5(gene name)|psi-mi:SLC25A5(display_short)|uniprotkb:ANT2(gene name synonym)|uniprotkb:Adenine nucleotide translocator 2(gene name synonym)|uniprotkb:ADP,ATP carrier protein 2(gene name synonym)|uniprotkb:Solute carrier family 25 member 5(gene name synonym)|uniprotkb:ADP,ATP carrier protein, fibroblast isoform(gene name synonym)|uniprotkb:AAC2(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Di et al. (2018) pubmed:29858488|imex:IM-28178 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-25617558|imex:IM-28178-11 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001170946.1|refseq:NP_689794.1|go:"GO:0090023"(positive regulation of neutrophil chemotaxis)|go:"GO:0090026"(positive regulation of monocyte chemotaxis)|go:"GO:0140284"(endoplasmic reticulum-endosome membrane contact site)|interpro:IPR000535(Major sperm protein)|interpro:IPR001251(Cellular retinaldehyde-binding/triple function, C-terminal)|interpro:IPR008962(PapD-like)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR036273|interpro:IPR036865|mint:Q8NHP6|rcsb pdb:6TQS|rcsb pdb:6TQT|rcsb pdb:6TQU|reactome:R-HSA-6798695|reactome:R-HSA-9013405|ensembl:ENSG00000130150(gene)|ensembl:ENST00000380492(transcript)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006935"(chemotaxis)|go:"GO:0016020"(membrane)|go:"GO:0035579"(specific granule membrane)|go:"GO:0044232"(organelle membrane contact site) refseq:NP_001143.2|reactome:R-HSA-83936|reactome:R-HSA-180897|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005757"(mitochondrial permeability transition pore complex)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0007059"(chromosome segregation)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0015078"(proton transmembrane transporter activity)|go:"GO:0015207"(adenine transmembrane transporter activity)|go:"GO:0016020"(membrane)|go:"GO:0017077"(oxidative phosphorylation uncoupler activity)|go:"GO:0030183"(B cell differentiation)|go:"GO:0030218"(erythrocyte differentiation)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0042645"(mitochondrial nucleoid)|go:"GO:0045121"(membrane raft)|go:"GO:0046902"(regulation of mitochondrial membrane permeability)|go:"GO:0051503"(adenine nucleotide transport)|go:"GO:0071817"(MMXD complex)|go:"GO:0140021"(mitochondrial ADP transmembrane transport)|go:"GO:1901029"(negative regulation of mitochondrial outer membrane permeabilization involved in apoptotic signaling pathway)|go:"GO:1901526"(positive regulation of mitophagy)|go:"GO:1990544"(mitochondrial ATP transmembrane transport)|go:"GO:1990830"(cellular response to leukemia inhibitory factor)|go:"GO:1990845"(adaptive thermogenesis)|interpro:IPR002067(Mitochondrial carrier protein)|interpro:IPR002113(Adenine nucleotide translocator 1)|interpro:IPR018108|interpro:IPR023395|mint:P05141|go:"GO:0005739"(mitochondrion)|ensembl:ENSG00000005022(gene)|ensembl:ENST00000317881(transcript)|go:"GO:0000295"(adenine nucleotide transmembrane transporter activity)|go:"GO:0003723"(RNA binding)|go:"GO:0005471"("ATP:ADP antiporter activity")|go:"GO:0005634"(nucleus)|dip:DIP-33873N - - - figure legend:Fig. 5A, Supp. Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells) - 2020/05/21 2021/04/12 rogid:WEdwMYKpu1uQll5NXnMm4P51R4E9606 rogid:8b4IQKtL2FJG/MS/5+mJUJrggYc9606 rigid:1P63pNv1yn3F27gcT2OsGH/3EDQ false green fluorescent protein tag:n-n|mutation disrupting interaction strength:406-406,404-404 - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q8NHP6 uniprotkb:Q7Z406 intact:EBI-2812848|uniprotkb:Q8NA83|uniprotkb:Q8N3H2|ensembl:ENSP00000369860 intact:EBI-355595|uniprotkb:Q5CZ75|uniprotkb:Q6XYE4|uniprotkb:Q76B62|uniprotkb:Q8WV23|uniprotkb:Q96I22|uniprotkb:Q9BT27|uniprotkb:Q9BW35|uniprotkb:Q9H882|uniprotkb:B0I1S2|ensembl:ENSP00000366169|ensembl:ENSP00000472819|uniprotkb:C3TTN4 psi-mi:mspd2_human(display_long)|uniprotkb:MOSPD2(gene name)|psi-mi:MOSPD2(display_short) psi-mi:myh14_human(display_long)|uniprotkb:MYH14(gene name)|psi-mi:MYH14(display_short)|uniprotkb:KIAA2034(gene name synonym)|uniprotkb:FP17425(orf name)|uniprotkb:Myosin heavy chain 14(gene name synonym)|uniprotkb:Myosin heavy chain, non-muscle IIc(gene name synonym)|uniprotkb:Non-muscle myosin heavy chain IIc(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Di et al. (2018) pubmed:29858488|imex:IM-28178 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-25617558|imex:IM-28178-11 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001170946.1|refseq:NP_689794.1|go:"GO:0090023"(positive regulation of neutrophil chemotaxis)|go:"GO:0090026"(positive regulation of monocyte chemotaxis)|go:"GO:0140284"(endoplasmic reticulum-endosome membrane contact site)|interpro:IPR000535(Major sperm protein)|interpro:IPR001251(Cellular retinaldehyde-binding/triple function, C-terminal)|interpro:IPR008962(PapD-like)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR036273|interpro:IPR036865|mint:Q8NHP6|rcsb pdb:6TQS|rcsb pdb:6TQT|rcsb pdb:6TQU|reactome:R-HSA-6798695|reactome:R-HSA-9013405|ensembl:ENSG00000130150(gene)|ensembl:ENST00000380492(transcript)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006935"(chemotaxis)|go:"GO:0016020"(membrane)|go:"GO:0035579"(specific granule membrane)|go:"GO:0044232"(organelle membrane contact site) refseq:NP_001070654.1|refseq:NP_001139281.1|refseq:NP_079005.3|refseq:XP_011525625.1|ensembl:ENSG00000105357(gene)|ensembl:ENST00000376970(transcript)|ensembl:ENST00000596571(transcript)|go:"GO:0000146"(microfilament motor activity)|go:"GO:0001725"(stress fiber)|go:"GO:0003009"(skeletal muscle contraction)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005829"(cytosol)|go:"GO:0005903"(brush border)|go:"GO:0007519"(skeletal muscle tissue development)|go:"GO:0007605"(sensory perception of sound)|go:"GO:0008360"(regulation of cell shape)|go:"GO:0016020"(membrane)|go:"GO:0016460"(myosin II complex)|go:"GO:0016887"(ATP hydrolysis activity)|go:"GO:0019228"(neuronal action potential)|go:"GO:0030048"(actin filament-based movement)|go:"GO:0030426"(growth cone)|go:"GO:0031032"(actomyosin structure organization)|go:"GO:0042641"(actomyosin)|go:"GO:0051015"(actin filament binding)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070584"(mitochondrion morphogenesis)|go:"GO:0071625"(vocalization behavior)|go:"GO:0097513"(myosin II filament)|interpro:IPR000048(IQ calmodulin-binding region)|interpro:IPR001609(Myosin head, motor region)|interpro:IPR004009(Myosin, N-terminal, SH3-like)|interpro:IPR008989(Myosin S1 fragment, N-terminal)|interpro:IPR027417|interpro:IPR036961|mint:Q7Z406|rcsb pdb:5I4E|rcsb pdb:5JLH|reactome:R-HSA-3928663|reactome:R-HSA-416572|reactome:R-HSA-5625740|reactome:R-HSA-5625900|reactome:R-HSA-5627117|reactome:R-HSA-5627123|interpro:IPR002928(Myosin tail)|refseq:XP_006723449.1|dip:DIP-33170N - - - figure legend:Fig. 5A, Supp. Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells) - 2020/05/21 2021/04/12 rogid:WEdwMYKpu1uQll5NXnMm4P51R4E9606 rogid:6aY3HPa5DIY5UadiOTTh/uSPi/M9606 rigid:1P63pNv1yn3F27gcT2OsGH/3EDQ false green fluorescent protein tag:n-n|mutation disrupting interaction strength:406-406,404-404 - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q8NHP6 uniprotkb:P09874 intact:EBI-2812848|uniprotkb:Q8NA83|uniprotkb:Q8N3H2|ensembl:ENSP00000369860 intact:EBI-355676|uniprotkb:Q8IUZ9|uniprotkb:B1ANJ4|ensembl:ENSP00000355759 psi-mi:mspd2_human(display_long)|uniprotkb:MOSPD2(gene name)|psi-mi:MOSPD2(display_short) psi-mi:parp1_human(display_long)|uniprotkb:PARP1(gene name)|psi-mi:PARP1(display_short)|uniprotkb:ADPRT(gene name synonym)|uniprotkb:PPOL(gene name synonym)|uniprotkb:"NAD(+) ADP-ribosyltransferase 1"(gene name synonym)|uniprotkb:Poly[ADP-ribose] synthase 1(gene name synonym)|uniprotkb:ADP-ribosyltransferase diphtheria toxin-like 1(gene name synonym)|uniprotkb:DNA ADP-ribosyltransferase PARP1(gene name synonym)|uniprotkb:Protein poly-ADP-ribosyltransferase PARP1(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Di et al. (2018) pubmed:29858488|imex:IM-28178 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-25617558|imex:IM-28178-11 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001170946.1|refseq:NP_689794.1|go:"GO:0090023"(positive regulation of neutrophil chemotaxis)|go:"GO:0090026"(positive regulation of monocyte chemotaxis)|go:"GO:0140284"(endoplasmic reticulum-endosome membrane contact site)|interpro:IPR000535(Major sperm protein)|interpro:IPR001251(Cellular retinaldehyde-binding/triple function, C-terminal)|interpro:IPR008962(PapD-like)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR036273|interpro:IPR036865|mint:Q8NHP6|rcsb pdb:6TQS|rcsb pdb:6TQT|rcsb pdb:6TQU|reactome:R-HSA-6798695|reactome:R-HSA-9013405|ensembl:ENSG00000130150(gene)|ensembl:ENST00000380492(transcript)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006935"(chemotaxis)|go:"GO:0016020"(membrane)|go:"GO:0035579"(specific granule membrane)|go:"GO:0044232"(organelle membrane contact site) refseq:NP_001609.2|rcsb pdb:7AAC|rcsb pdb:7AAD|rcsb pdb:6NRJ|rcsb pdb:6NTU|rcsb pdb:7CMW|rcsb pdb:6VKK|rcsb pdb:7KK2|rcsb pdb:7KK3|rcsb pdb:7KK4|rcsb pdb:7KK5|rcsb pdb:7KK6|reactome:R-HSA-110362|reactome:R-HSA-192814|reactome:R-HSA-2173795|reactome:R-HSA-3108214|reactome:R-HSA-5685939|reactome:R-HSA-5696394|reactome:R-HSA-5696395|reactome:R-HSA-5696400|rcsb pdb:6VKO|rcsb pdb:6VKQ|rcsb pdb:6XVW|rcsb pdb:7AAA|rcsb pdb:7AAB|ensembl:ENSG00000143799(gene)|ensembl:ENST00000366794(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000723"(telomere maintenance)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0003677"(DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0003950"(NAD+ ADP-ribosyltransferase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005730"(nucleolus)|go:"GO:0005739"(mitochondrion)|go:"GO:0006281"(DNA repair)|go:"GO:0006302"(double-strand break repair)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0006471"(protein ADP-ribosylation)|go:"GO:0006915"(apoptotic process)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0007005"(mitochondrion organization)|go:"GO:0007179"(transforming growth factor beta receptor signaling pathway)|go:"GO:0008134"(transcription factor binding)|go:"GO:0010332"(response to gamma radiation)|go:"GO:0010613"(positive regulation of cardiac muscle hypertrophy)|go:"GO:0010990"(regulation of SMAD protein complex assembly)|go:"GO:0016020"(membrane)|go:"GO:0016540"(protein autoprocessing)|go:"GO:0016604"(nuclear body)|go:"GO:0018312"(peptidyl-serine ADP-ribosylation)|go:"GO:0018424"(peptidyl-glutamic acid poly-ADP-ribosylation)|go:"GO:0019899"(enzyme binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0023019"(signal transduction involved in regulation of gene expression)|go:"GO:0030225"(macrophage differentiation)|go:"GO:0030331"(estrogen receptor binding)|go:"GO:0030592"(DNA ADP-ribosylation)|go:"GO:0032042"(mitochondrial DNA metabolic process)|go:"GO:0032869"(cellular response to insulin stimulus)|go:"GO:0032991"(protein-containing complex)|go:"GO:0008270"(zinc ion binding)|go:"GO:0035861"(site of double-strand break)|go:"GO:0036211"(protein modification process)|go:"GO:0042769"(obsolete DNA damage response, detection of DNA damage)|go:"GO:0042802"(identical protein binding)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0043504"(mitochondrial DNA repair)|go:"GO:0044030"(regulation of DNA methylation)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0047485"(protein N-terminus binding)|go:"GO:0050790"(regulation of catalytic activity)|go:"GO:0051287"(NAD binding)|go:"GO:0051901"(positive regulation of mitochondrial depolarization)|go:"GO:0060391"(positive regulation of SMAD protein signal transduction)|go:"GO:0070212"(protein poly-ADP-ribosylation)|go:"GO:0032993"(protein-DNA complex)|go:"GO:0033148"(positive regulation of intracellular estrogen receptor signaling pathway)|go:"GO:0070213"(protein auto-ADP-ribosylation)|go:"GO:0034599"(cellular response to oxidative stress)|go:"GO:0070412"(R-SMAD binding)|go:"GO:0034644"(cellular response to UV)|go:"GO:0071294"(cellular response to zinc ion)|go:"GO:0090734"(site of DNA damage)|go:"GO:0140294"(NAD DNA ADP-ribosyltransferase activity)|go:"GO:1900182"(positive regulation of protein localization to nucleus)|go:"GO:1901216"(positive regulation of neuron death)|go:"GO:1903376"(regulation of oxidative stress-induced neuron intrinsic apoptotic signaling pathway)|go:"GO:1903518"(positive regulation of single strand break repair)|go:"GO:1904044"(response to aldosterone)|go:"GO:1904357"(negative regulation of telomere maintenance via telomere lengthening)|go:"GO:1904646"(cellular response to amyloid-beta)|go:"GO:1904762"(positive regulation of myofibroblast differentiation)|go:"GO:1905168"(positive regulation of double-strand break repair via homologous recombination)|go:"GO:1990404"(protein ADP-ribosylase activity)|go:"GO:1990966"(ATP generation from poly-ADP-D-ribose)|go:"GO:2000679"(positive regulation of transcription regulatory region DNA binding)|go:"GO:2001170"(negative regulation of ATP biosynthetic process)|interpro:IPR001357(BRCT)|interpro:IPR001510(Zinc finger, PARP-type)|interpro:IPR004102("Poly(ADP-ribose) polymerase, regulatory region")|interpro:IPR008288(NAD+ ADP-ribosyltransferase)|interpro:IPR008893(WGR)|interpro:IPR012317("Poly(ADP-ribose) polymerase, catalytic region")|interpro:IPR012982(PADR1)|interpro:IPR036420|interpro:IPR036616|interpro:IPR036930|interpro:IPR036957|interpro:IPR038650|mint:P09874|rcsb pdb:1UK0|rcsb pdb:1UK1|rcsb pdb:1WOK|rcsb pdb:2COK|rcsb pdb:2CR9|rcsb pdb:2CS2|rcsb pdb:2DMJ|rcsb pdb:2JVN|go:"GO:1903827"|rcsb pdb:2L30|rcsb pdb:2N8A|rcsb pdb:2RCW|rcsb pdb:2RD6|rcsb pdb:2RIQ|rcsb pdb:2L31|rcsb pdb:3GJW|rcsb pdb:3GN7|rcsb pdb:3L3L|rcsb pdb:3L3M|rcsb pdb:3OD8|rcsb pdb:3ODA|rcsb pdb:3ODC|rcsb pdb:3ODE|rcsb pdb:4AV1|rcsb pdb:4DQY|rcsb pdb:4GV7|rcsb pdb:4HHY|rcsb pdb:4HHZ|rcsb pdb:4L6S|rcsb pdb:4OPX|rcsb pdb:4OQA|rcsb pdb:4OQB|rcsb pdb:4PJT|rcsb pdb:4R5W|rcsb pdb:4R6E|rcsb pdb:4RV6|rcsb pdb:4UND|rcsb pdb:4UXB|rcsb pdb:4XHU|rcsb pdb:5A00|rcsb pdb:5DS3|rcsb pdb:5HA9|rcsb pdb:5KPN|rcsb pdb:5KPO|rcsb pdb:5KPP|rcsb pdb:5KPQ|rcsb pdb:5WRQ|rcsb pdb:5WRY|rcsb pdb:5WRZ|rcsb pdb:5WS0|rcsb pdb:5WS1|rcsb pdb:5WTC|rcsb pdb:4ZZZ|rcsb pdb:5XSR|rcsb pdb:5XST|rcsb pdb:5XSU|rcsb pdb:6BHV|rcsb pdb:6GHK|rcsb pdb:6M3I|rcsb pdb:6NRF|rcsb pdb:6NRG|rcsb pdb:6NRH|rcsb pdb:6NRI|dip:DIP-38N - - - figure legend:Fig. 5A, Supp. Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells) - 2020/05/21 2021/04/12 rogid:WEdwMYKpu1uQll5NXnMm4P51R4E9606 rogid:VC+4HLilGJuoiTbk4/fSeRw9+iY9606 rigid:1P63pNv1yn3F27gcT2OsGH/3EDQ false green fluorescent protein tag:n-n|mutation disrupting interaction strength:406-406,404-404 - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q8NHP6 uniprotkb:P61353 intact:EBI-2812848|uniprotkb:Q8NA83|uniprotkb:Q8N3H2|ensembl:ENSP00000369860 intact:EBI-352760|uniprotkb:P08526|uniprotkb:Q4G0A9|ensembl:ENSP00000253788|ensembl:ENSP00000464813|ensembl:ENSP00000467587 psi-mi:mspd2_human(display_long)|uniprotkb:MOSPD2(gene name)|psi-mi:MOSPD2(display_short) psi-mi:rl27_human(display_long)|uniprotkb:RPL27(gene name)|psi-mi:RPL27(display_short)|uniprotkb:Large ribosomal subunit protein eL27(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Di et al. (2018) pubmed:29858488|imex:IM-28178 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-25617558|imex:IM-28178-11 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001170946.1|refseq:NP_689794.1|go:"GO:0090023"(positive regulation of neutrophil chemotaxis)|go:"GO:0090026"(positive regulation of monocyte chemotaxis)|go:"GO:0140284"(endoplasmic reticulum-endosome membrane contact site)|interpro:IPR000535(Major sperm protein)|interpro:IPR001251(Cellular retinaldehyde-binding/triple function, C-terminal)|interpro:IPR008962(PapD-like)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR036273|interpro:IPR036865|mint:Q8NHP6|rcsb pdb:6TQS|rcsb pdb:6TQT|rcsb pdb:6TQU|reactome:R-HSA-6798695|reactome:R-HSA-9013405|ensembl:ENSG00000130150(gene)|ensembl:ENST00000380492(transcript)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006935"(chemotaxis)|go:"GO:0016020"(membrane)|go:"GO:0035579"(specific granule membrane)|go:"GO:0044232"(organelle membrane contact site) rcsb pdb:6OLG|rcsb pdb:6OLI|rcsb pdb:6OLZ|rcsb pdb:6OM0|rcsb pdb:6OLF|rcsb pdb:6OM7|rcsb pdb:6QZP|rcsb pdb:6W6L|rcsb pdb:6XA1|rcsb pdb:6Y0G|rcsb pdb:6Y2L|rcsb pdb:6Y57|rcsb pdb:6Y6X|rcsb pdb:6Z6L|rcsb pdb:6Z6M|rcsb pdb:6Z6N|rcsb pdb:6ZM7|rcsb pdb:6ZME|rcsb pdb:6ZMI|rcsb pdb:6ZMO|rcsb pdb:7BHP|reactome:R-HSA-156827|reactome:R-HSA-156902|reactome:R-HSA-1799339|reactome:R-HSA-192823|reactome:R-HSA-2408557|reactome:R-HSA-6791226|reactome:R-HSA-72689|reactome:R-HSA-72706|reactome:R-HSA-72764|reactome:R-HSA-9010553|reactome:R-HSA-9633012|reactome:R-HSA-975956|reactome:R-HSA-975957|refseq:NP_000979.1|ensembl:ENSG00000131469(gene)|ensembl:ENST00000253788(transcript)|ensembl:ENST00000589037(transcript)|ensembl:ENST00000589913(transcript)|go:"GO:0002181"(cytoplasmic translation)|go:"GO:0003723"(RNA binding)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0005840"(ribosome)|go:"GO:0005925"(focal adhesion)|go:"GO:0006364"(rRNA processing)|go:"GO:0006412"(translation)|go:"GO:0016020"(membrane)|go:"GO:0022625"(cytosolic large ribosomal subunit)|go:"GO:0022626"(cytosolic ribosome)|rcsb pdb:6LQM|rcsb pdb:6LSR|rcsb pdb:6LSS|rcsb pdb:6LU8|go:"GO:0070062"(extracellular exosome)|go:"GO:0098556"(cytoplasmic side of rough endoplasmic reticulum membrane)|go:"GO:1904044"(response to aldosterone)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR001141(Ribosomal protein L27e)|interpro:IPR005824(KOW)|interpro:IPR008991(Translation protein SH3-like)|interpro:IPR018262|interpro:IPR038655|interpro:IPR041991|mint:P61353|rcsb pdb:4UG0|rcsb pdb:4V6X|rcsb pdb:5AJ0|rcsb pdb:5LKS|rcsb pdb:5T2C|rcsb pdb:6EK0|rcsb pdb:6IP5|rcsb pdb:6IP6|rcsb pdb:6IP8|rcsb pdb:6OLE - - - figure legend:Fig. 5A, Supp. Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells) - 2020/05/21 2021/04/12 rogid:WEdwMYKpu1uQll5NXnMm4P51R4E9606 rogid:TLWbAcdRKUb2ijDYjSUa1sbixis9606 rigid:1P63pNv1yn3F27gcT2OsGH/3EDQ false green fluorescent protein tag:n-n|mutation disrupting interaction strength:406-406,404-404 - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q8NHP6 uniprotkb:Q13200 intact:EBI-2812848|uniprotkb:Q8NA83|uniprotkb:Q8N3H2|ensembl:ENSP00000369860 intact:EBI-357648|uniprotkb:B4DX07|uniprotkb:B4DXY1|uniprotkb:E7EW34|uniprotkb:E9PCS3|uniprotkb:Q12932|uniprotkb:Q15321|uniprotkb:Q96I12|ensembl:ENSP00000310129|uniprotkb:Q53XQ4 psi-mi:mspd2_human(display_long)|uniprotkb:MOSPD2(gene name)|psi-mi:MOSPD2(display_short) psi-mi:psmd2_human(display_long)|uniprotkb:PSMD2(gene name)|psi-mi:PSMD2(display_short)|uniprotkb:TRAP2(gene name synonym)|uniprotkb:26S proteasome regulatory subunit RPN1(gene name synonym)|uniprotkb:26S proteasome regulatory subunit S2(gene name synonym)|uniprotkb:26S proteasome subunit p97(gene name synonym)|uniprotkb:Tumor necrosis factor type 1 receptor-associated protein 2(gene name synonym)|uniprotkb:Protein 55.11(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Di et al. (2018) pubmed:29858488|imex:IM-28178 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-25617558|imex:IM-28178-11 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001170946.1|refseq:NP_689794.1|go:"GO:0090023"(positive regulation of neutrophil chemotaxis)|go:"GO:0090026"(positive regulation of monocyte chemotaxis)|go:"GO:0140284"(endoplasmic reticulum-endosome membrane contact site)|interpro:IPR000535(Major sperm protein)|interpro:IPR001251(Cellular retinaldehyde-binding/triple function, C-terminal)|interpro:IPR008962(PapD-like)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR036273|interpro:IPR036865|mint:Q8NHP6|rcsb pdb:6TQS|rcsb pdb:6TQT|rcsb pdb:6TQU|reactome:R-HSA-6798695|reactome:R-HSA-9013405|ensembl:ENSG00000130150(gene)|ensembl:ENST00000380492(transcript)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006935"(chemotaxis)|go:"GO:0016020"(membrane)|go:"GO:0035579"(specific granule membrane)|go:"GO:0044232"(organelle membrane contact site) refseq:NP_001265637.1|refseq:NP_001265638.1|refseq:NP_002799.3|ensembl:ENSG00000175166(gene)|ensembl:ENST00000310118(transcript)|go:"GO:0000502"(proteasome complex)|go:"GO:0005576"(extracellular region)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005838"(proteasome regulatory particle)|go:"GO:0008540"(proteasome regulatory particle, base subcomplex)|go:"GO:0016020"(membrane)|go:"GO:0022624"(proteasome accessory complex)|go:"GO:0030234"(enzyme regulator activity)|go:"GO:0034515"(proteasome storage granule)|go:"GO:0034774"(secretory granule lumen)|go:"GO:0042176"(regulation of protein catabolic process)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0070062"(extracellular exosome)|go:"GO:1904813"(ficolin-1-rich granule lumen)|interpro:IPR002015(Proteasome/cyclosome, regulatory subunit)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR040892|interpro:IPR041433|mint:Q13200|rcsb pdb:5GJQ|rcsb pdb:5GJR|rcsb pdb:5L4K|rcsb pdb:5LN3|interpro:IPR016643(26S proteasome regulatory complex, non-ATPase subcomplex, Rpn1 subunit)|rcsb pdb:5T0C|rcsb pdb:5T0G|rcsb pdb:5T0H|rcsb pdb:5T0I|rcsb pdb:5T0J|rcsb pdb:5VFP|rcsb pdb:5VFQ|rcsb pdb:5VFR|rcsb pdb:5VFS|rcsb pdb:5VFT|rcsb pdb:5VFU|rcsb pdb:5VHF|rcsb pdb:5VHH|rcsb pdb:5VHI|rcsb pdb:5VHJ|reactome:R-HSA-9020702|reactome:R-HSA-9604323|reactome:R-HSA-983168|reactome:R-HSA-9010553|rcsb pdb:5VHM|rcsb pdb:6MSG|rcsb pdb:6MSH|rcsb pdb:5VHN|rcsb pdb:5VHO|rcsb pdb:5VHP|rcsb pdb:6MSJ|rcsb pdb:6MSK|rcsb pdb:5VHQ|rcsb pdb:5VHR|rcsb pdb:5VHS|rcsb pdb:6WJD|rcsb pdb:6WJN|reactome:R-HSA-1169091|rcsb pdb:6MSB|rcsb pdb:6MSD|reactome:R-HSA-1234176|reactome:R-HSA-1236974|reactome:R-HSA-1236978|reactome:R-HSA-174084|reactome:R-HSA-174113|reactome:R-HSA-174154|reactome:R-HSA-174178|reactome:R-HSA-174184|reactome:R-HSA-180534|reactome:R-HSA-180585|reactome:R-HSA-187577|reactome:R-HSA-195253|reactome:R-HSA-202424|reactome:R-HSA-211733|reactome:R-HSA-2467813|reactome:R-HSA-5676590|reactome:R-HSA-5678895|reactome:R-HSA-5687128|reactome:R-HSA-2871837|reactome:R-HSA-349425|reactome:R-HSA-350562|reactome:R-HSA-382556|reactome:R-HSA-450408|reactome:R-HSA-4608870|reactome:R-HSA-4641257|reactome:R-HSA-4641258|reactome:R-HSA-5358346|reactome:R-HSA-5689603|reactome:R-HSA-5689880|reactome:R-HSA-5362768|reactome:R-HSA-5607761|reactome:R-HSA-5607764|reactome:R-HSA-5610780|reactome:R-HSA-5610783|reactome:R-HSA-5610785|reactome:R-HSA-5632684|reactome:R-HSA-5658442|reactome:R-HSA-6798695|reactome:R-HSA-68827|reactome:R-HSA-68949|reactome:R-HSA-69017|reactome:R-HSA-69481|reactome:R-HSA-69601|reactome:R-HSA-75815|reactome:R-HSA-8852276|reactome:R-HSA-8854050|reactome:R-HSA-8932339|reactome:R-HSA-8939236|reactome:R-HSA-8939902|reactome:R-HSA-8941858|reactome:R-HSA-8948751|reactome:R-HSA-8951664|reactome:R-HSA-5668541|dip:DIP-38204N - - - figure legend:Fig. 5A, Supp. Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells) - 2020/05/21 2021/04/12 rogid:WEdwMYKpu1uQll5NXnMm4P51R4E9606 rogid:wujS1i4Gs3gWNinOey4oKsshA+g9606 rigid:1P63pNv1yn3F27gcT2OsGH/3EDQ false green fluorescent protein tag:n-n|mutation disrupting interaction strength:406-406,404-404 - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q8NHP6 uniprotkb:P61026 intact:EBI-2812848|uniprotkb:Q8NA83|uniprotkb:Q8N3H2|ensembl:ENSP00000369860 intact:EBI-726075|uniprotkb:O88386|uniprotkb:Q6IA52|uniprotkb:Q9D7X6|uniprotkb:Q9H0T3|uniprotkb:D6W538|ensembl:ENSP00000264710 psi-mi:mspd2_human(display_long)|uniprotkb:MOSPD2(gene name)|psi-mi:MOSPD2(display_short) psi-mi:rab10_human(display_long)|uniprotkb:RAB10(gene name)|psi-mi:RAB10(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Di et al. (2018) pubmed:29858488|imex:IM-28178 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-25617558|imex:IM-28178-11 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001170946.1|refseq:NP_689794.1|go:"GO:0090023"(positive regulation of neutrophil chemotaxis)|go:"GO:0090026"(positive regulation of monocyte chemotaxis)|go:"GO:0140284"(endoplasmic reticulum-endosome membrane contact site)|interpro:IPR000535(Major sperm protein)|interpro:IPR001251(Cellular retinaldehyde-binding/triple function, C-terminal)|interpro:IPR008962(PapD-like)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR036273|interpro:IPR036865|mint:Q8NHP6|rcsb pdb:6TQS|rcsb pdb:6TQT|rcsb pdb:6TQU|reactome:R-HSA-6798695|reactome:R-HSA-9013405|ensembl:ENSG00000130150(gene)|ensembl:ENST00000380492(transcript)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006935"(chemotaxis)|go:"GO:0016020"(membrane)|go:"GO:0035579"(specific granule membrane)|go:"GO:0044232"(organelle membrane contact site) refseq:NP_057215.3|go:"GO:0006904"(vesicle docking involved in exocytosis)|go:"GO:0007409"(axonogenesis)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0009306"(protein secretion)|go:"GO:0016192"(vesicle-mediated transport)|go:"GO:0016197"(endosomal transport)|go:"GO:0017157"(regulation of exocytosis)|go:"GO:0019003"(GDP binding)|go:"GO:0019882"(antigen processing and presentation)|go:"GO:0030659"(cytoplasmic vesicle membrane)|go:"GO:0030667"(secretory granule membrane)|go:"GO:0030670"(phagocytic vesicle membrane)|go:"GO:0030859"(polarized epithelial cell differentiation)|go:"GO:0031489"(myosin V binding)|go:"GO:0032593"(insulin-responsive compartment)|go:"GO:0032869"(cellular response to insulin stimulus)|go:"GO:0043001"(Golgi to plasma membrane protein transport)|go:"GO:0045055"(regulated exocytosis)|go:"GO:0045200"(establishment of neuroblast polarity)|go:"GO:0006893"(Golgi to plasma membrane transport)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0055037"(recycling endosome)|go:"GO:0055038"(recycling endosome membrane)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070382"(exocytic vesicle)|go:"GO:0071782"(endoplasmic reticulum tubular network)|go:"GO:0071786"(endoplasmic reticulum tubular network organization)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0090150"(establishment of protein localization to membrane)|go:"GO:0097051"(establishment of protein localization to endoplasmic reticulum membrane)|go:"GO:0098641"(cadherin binding involved in cell-cell adhesion)|go:"GO:1903361"(protein localization to basolateral plasma membrane)|interpro:IPR001806(Ras GTPase)|interpro:IPR005225(Small GTP-binding protein)|interpro:IPR027417|rcsb pdb:5LPN|rcsb pdb:5SZJ|reactome:R-HSA-1445148|reactome:R-HSA-6798695|reactome:R-HSA-8873719|reactome:R-HSA-8876198|ensembl:ENSG00000084733(gene)|ensembl:ENST00000264710(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0003925"(G protein activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005768"(endosome)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005886"(plasma membrane)|go:"GO:0005912"(adherens junction)|go:"GO:0005925"(focal adhesion)|go:"GO:0005929"(cilium) - - - figure legend:Fig. 5A, Supp. Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells) - 2020/05/21 2021/04/12 rogid:WEdwMYKpu1uQll5NXnMm4P51R4E9606 rogid:ZbfLtWtXl3z6/MYyhiZp6P1Y5tE9606 rigid:1P63pNv1yn3F27gcT2OsGH/3EDQ false green fluorescent protein tag:n-n|mutation disrupting interaction strength:406-406,404-404 - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q8NHP6 uniprotkb:F5GY55 intact:EBI-2812848|uniprotkb:Q8NA83|uniprotkb:Q8N3H2|ensembl:ENSP00000369860 intact:EBI-25617913|ensembl:ENSP00000440269 psi-mi:mspd2_human(display_long)|uniprotkb:MOSPD2(gene name)|psi-mi:MOSPD2(display_short) psi-mi:f5gy55_human(display_long)|uniprotkb:DDB1(gene name)|psi-mi:DDB1(display_short)|uniprotkb:Damage-specific DNA-binding protein 1(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Di et al. (2018) pubmed:29858488|imex:IM-28178 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-25617558|imex:IM-28178-11 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001170946.1|refseq:NP_689794.1|go:"GO:0090023"(positive regulation of neutrophil chemotaxis)|go:"GO:0090026"(positive regulation of monocyte chemotaxis)|go:"GO:0140284"(endoplasmic reticulum-endosome membrane contact site)|interpro:IPR000535(Major sperm protein)|interpro:IPR001251(Cellular retinaldehyde-binding/triple function, C-terminal)|interpro:IPR008962(PapD-like)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR036273|interpro:IPR036865|mint:Q8NHP6|rcsb pdb:6TQS|rcsb pdb:6TQT|rcsb pdb:6TQU|reactome:R-HSA-6798695|reactome:R-HSA-9013405|ensembl:ENSG00000130150(gene)|ensembl:ENST00000380492(transcript)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006935"(chemotaxis)|go:"GO:0016020"(membrane)|go:"GO:0035579"(specific granule membrane)|go:"GO:0044232"(organelle membrane contact site) ensembl:ENSG00000167986(gene)|ensembl:ENST00000540166(transcript)|go:"GO:0003676"(nucleic acid binding)|go:"GO:0005634"(nucleus)|go:"GO:0006281"(DNA repair)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|interpro:IPR004871(Cleavage and polyadenylation specificity factor, A subunit, C-terminal)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR018846|interpro:IPR031297|interpro:IPR036322 - - - figure legend:Fig. 5A, Supp. Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells) - 2020/05/21 2021/04/12 rogid:WEdwMYKpu1uQll5NXnMm4P51R4E9606 rogid:lpdAFZH8gGptHKWygoapA+Zz0AI9606 rigid:1P63pNv1yn3F27gcT2OsGH/3EDQ false green fluorescent protein tag:n-n|mutation disrupting interaction strength:406-406,404-404 - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q8NHP6 uniprotkb:B1AK87 intact:EBI-2812848|uniprotkb:Q8NA83|uniprotkb:Q8N3H2|ensembl:ENSP00000369860 intact:EBI-25617896|ensembl:ENSP00000364286 psi-mi:mspd2_human(display_long)|uniprotkb:MOSPD2(gene name)|psi-mi:MOSPD2(display_short) psi-mi:b1ak87_human(display_long)|uniprotkb:CAPZB(gene name)|psi-mi:CAPZB(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Di et al. (2018) pubmed:29858488|imex:IM-28178 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-25617558|imex:IM-28178-11 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001170946.1|refseq:NP_689794.1|go:"GO:0090023"(positive regulation of neutrophil chemotaxis)|go:"GO:0090026"(positive regulation of monocyte chemotaxis)|go:"GO:0140284"(endoplasmic reticulum-endosome membrane contact site)|interpro:IPR000535(Major sperm protein)|interpro:IPR001251(Cellular retinaldehyde-binding/triple function, C-terminal)|interpro:IPR008962(PapD-like)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR036273|interpro:IPR036865|mint:Q8NHP6|rcsb pdb:6TQS|rcsb pdb:6TQT|rcsb pdb:6TQU|reactome:R-HSA-6798695|reactome:R-HSA-9013405|ensembl:ENSG00000130150(gene)|ensembl:ENST00000380492(transcript)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006935"(chemotaxis)|go:"GO:0016020"(membrane)|go:"GO:0035579"(specific granule membrane)|go:"GO:0044232"(organelle membrane contact site) ensembl:ENSG00000077549(gene)|ensembl:ENST00000375144(transcript)|go:"GO:0003779"(actin binding)|go:"GO:0008290"(F-actin capping protein complex)|go:"GO:0030017"(sarcomere)|go:"GO:0030036"(actin cytoskeleton organization)|go:"GO:0051016"(barbed-end actin filament capping)|interpro:IPR001698(F-actin capping protein, beta subunit)|interpro:IPR019771|interpro:IPR037282|interpro:IPR042276|interpro:IPR043175 - - - figure legend:Fig. 5A, Supp. Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells) - 2020/05/21 2021/04/12 rogid:WEdwMYKpu1uQll5NXnMm4P51R4E9606 rogid:VGPdYqWZuzoDXa7rNOuk2vhMoIM9606 rigid:1P63pNv1yn3F27gcT2OsGH/3EDQ false green fluorescent protein tag:n-n|mutation disrupting interaction strength:406-406,404-404 - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q8NHP6 uniprotkb:Q96CS3 intact:EBI-2812848|uniprotkb:Q8NA83|uniprotkb:Q8N3H2|ensembl:ENSP00000369860 intact:EBI-1055805|uniprotkb:O94963|uniprotkb:Q8IUF2|uniprotkb:Q9BRP2|uniprotkb:Q9BVM7|ensembl:ENSP00000261942 psi-mi:mspd2_human(display_long)|uniprotkb:MOSPD2(gene name)|psi-mi:MOSPD2(display_short) psi-mi:faf2_human(display_long)|uniprotkb:Protein ETEA(gene name synonym)|uniprotkb:FAF2(gene name)|psi-mi:FAF2(display_short)|uniprotkb:ETEA(gene name synonym)|uniprotkb:KIAA0887(gene name synonym)|uniprotkb:UBXD8(gene name synonym)|uniprotkb:UBXN3B(gene name synonym)|uniprotkb:UBX domain-containing protein 3B(gene name synonym)|uniprotkb:UBX domain-containing protein 8(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Di et al. (2018) pubmed:29858488|imex:IM-28178 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-25617558|imex:IM-28178-11 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001170946.1|refseq:NP_689794.1|go:"GO:0090023"(positive regulation of neutrophil chemotaxis)|go:"GO:0090026"(positive regulation of monocyte chemotaxis)|go:"GO:0140284"(endoplasmic reticulum-endosome membrane contact site)|interpro:IPR000535(Major sperm protein)|interpro:IPR001251(Cellular retinaldehyde-binding/triple function, C-terminal)|interpro:IPR008962(PapD-like)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR036273|interpro:IPR036865|mint:Q8NHP6|rcsb pdb:6TQS|rcsb pdb:6TQT|rcsb pdb:6TQU|reactome:R-HSA-6798695|reactome:R-HSA-9013405|ensembl:ENSG00000130150(gene)|ensembl:ENST00000380492(transcript)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006935"(chemotaxis)|go:"GO:0016020"(membrane)|go:"GO:0035579"(specific granule membrane)|go:"GO:0044232"(organelle membrane contact site) refseq:NP_055428.1|ensembl:ENSP00000261942|ensembl:ENST00000261942(transcript)|go:"GO:0005576"(extracellular region)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005811"(lipid droplet)|go:"GO:0006986"(response to unfolded protein)|go:"GO:0030433"(ubiquitin-dependent ERAD pathway)|go:"GO:0030970"(retrograde protein transport, ER to cytosol)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0034098"(VCP-NPL4-UFD1 AAA ATPase complex)|go:"GO:0034389"(lipid droplet organization)|go:"GO:0035473"(lipase binding)|go:"GO:0035578"(azurophil granule lumen)|go:"GO:0043130"(ubiquitin binding)|go:"GO:0055102"(lipase inhibitor activity)|interpro:IPR001012(UBX)|interpro:IPR006577(UAS)|interpro:IPR009060(UBA-like)|interpro:IPR029071|interpro:IPR036249|mint:Q96CS3|rcsb pdb:2DAM|reactome:R-HSA-6798695|reactome:R-HSA-8980692|ensembl:ENSG00000113194(gene)|dip:DIP-46261N - - - figure legend:Fig. 5A, Supp. Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells) - 2020/05/21 2021/04/12 rogid:WEdwMYKpu1uQll5NXnMm4P51R4E9606 rogid:GCm7BqDpwxDW1iABu0cShmWHtZQ9606 rigid:1P63pNv1yn3F27gcT2OsGH/3EDQ false green fluorescent protein tag:n-n|mutation disrupting interaction strength:406-406,404-404 - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q8NHP6 uniprotkb:Q96KK5 intact:EBI-2812848|uniprotkb:Q8NA83|uniprotkb:Q8N3H2|ensembl:ENSP00000369860 intact:EBI-6147668|ensembl:ENSP00000366679 psi-mi:mspd2_human(display_long)|uniprotkb:MOSPD2(gene name)|psi-mi:MOSPD2(display_short) psi-mi:h2a1h_human(display_long)|uniprotkb:H2AC12(gene name)|psi-mi:H2AC12(display_short)|uniprotkb:H2A-clustered histone 12(gene name synonym)|uniprotkb:HIST1H2AH(gene name synonym)|uniprotkb:HIST1H2AI(gene name synonym)|uniprotkb:Histone H2A/s(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Di et al. (2018) pubmed:29858488|imex:IM-28178 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-25617558|imex:IM-28178-11 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001170946.1|refseq:NP_689794.1|go:"GO:0090023"(positive regulation of neutrophil chemotaxis)|go:"GO:0090026"(positive regulation of monocyte chemotaxis)|go:"GO:0140284"(endoplasmic reticulum-endosome membrane contact site)|interpro:IPR000535(Major sperm protein)|interpro:IPR001251(Cellular retinaldehyde-binding/triple function, C-terminal)|interpro:IPR008962(PapD-like)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR036273|interpro:IPR036865|mint:Q8NHP6|rcsb pdb:6TQS|rcsb pdb:6TQT|rcsb pdb:6TQU|reactome:R-HSA-6798695|reactome:R-HSA-9013405|ensembl:ENSG00000130150(gene)|ensembl:ENST00000380492(transcript)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006935"(chemotaxis)|go:"GO:0016020"(membrane)|go:"GO:0035579"(specific granule membrane)|go:"GO:0044232"(organelle membrane contact site) refseq:NP_542163.1|dip:DIP-61699N|ensembl:ENSG00000274997(gene)|ensembl:ENST00000377459(transcript)|go:"GO:0000786"(nucleosome)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0006342"|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0070062"(extracellular exosome)|interpro:IPR002119(Histone H2A)|interpro:IPR007125(Histone core)|interpro:IPR009072(Histone-fold)|interpro:IPR032454|interpro:IPR032458|reactome:R-HSA-3214815|reactome:R-HSA-3214847|reactome:R-HSA-3214858|reactome:R-HSA-5689603|reactome:R-HSA-5689880|reactome:R-HSA-5689901|reactome:R-HSA-9609690|reactome:R-HSA-9610379 - - - figure legend:Fig. 5A, Supp. Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells) - 2020/05/21 2021/04/12 rogid:WEdwMYKpu1uQll5NXnMm4P51R4E9606 rogid:Oa322n+evy8Cu0E9cWTEdYwQPKM9606 rigid:1P63pNv1yn3F27gcT2OsGH/3EDQ false green fluorescent protein tag:n-n|mutation disrupting interaction strength:406-406,404-404 - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q8NHP6 uniprotkb:P19338 intact:EBI-2812848|uniprotkb:Q8NA83|uniprotkb:Q8N3H2|ensembl:ENSP00000369860 intact:EBI-346967|uniprotkb:Q53SK1|uniprotkb:Q8NB06|uniprotkb:Q9UDG1|uniprotkb:Q9UCF0|intact:EBI-352553|ensembl:ENSP00000318195 psi-mi:mspd2_human(display_long)|uniprotkb:MOSPD2(gene name)|psi-mi:MOSPD2(display_short) psi-mi:nucl_human(display_long)|uniprotkb:NCL(gene name)|psi-mi:NCL(display_short)|uniprotkb:Protein C23(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Di et al. (2018) pubmed:29858488|imex:IM-28178 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-25617558|imex:IM-28178-11 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001170946.1|refseq:NP_689794.1|go:"GO:0090023"(positive regulation of neutrophil chemotaxis)|go:"GO:0090026"(positive regulation of monocyte chemotaxis)|go:"GO:0140284"(endoplasmic reticulum-endosome membrane contact site)|interpro:IPR000535(Major sperm protein)|interpro:IPR001251(Cellular retinaldehyde-binding/triple function, C-terminal)|interpro:IPR008962(PapD-like)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR036273|interpro:IPR036865|mint:Q8NHP6|rcsb pdb:6TQS|rcsb pdb:6TQT|rcsb pdb:6TQU|reactome:R-HSA-6798695|reactome:R-HSA-9013405|ensembl:ENSG00000130150(gene)|ensembl:ENST00000380492(transcript)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006935"(chemotaxis)|go:"GO:0016020"(membrane)|go:"GO:0035579"(specific granule membrane)|go:"GO:0044232"(organelle membrane contact site) refseq:NP_005372.2|dip:DIP-89N|ensembl:ENSG00000115053(gene)|ensembl:ENST00000322723(transcript)|go:"GO:0001525"(angiogenesis)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005681"(spliceosomal complex)|go:"GO:0005694"(chromosome)|go:"GO:0005730"(nucleolus)|go:"GO:0005938"(cell cortex)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0016020"(membrane)|go:"GO:0017148"(negative regulation of translation)|go:"GO:0036464"(cytoplasmic ribonucleoprotein granule)|go:"GO:0042162"(telomeric DNA binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0044547"(DNA topoisomerase binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048026"(positive regulation of mRNA splicing, via spliceosome)|go:"GO:0048027"(mRNA 5'-UTR binding)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071364"(cellular response to epidermal growth factor stimulus)|go:"GO:1901838"(positive regulation of transcription of nucleolar large rRNA by RNA polymerase I)|go:"GO:1990830"(cellular response to leukemia inhibitory factor)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR003954(RNA recognition, region 1)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR034230|interpro:IPR034233|interpro:IPR034234|interpro:IPR034235|interpro:IPR035979|mint:P19338|rcsb pdb:2FC8|rcsb pdb:2FC9|rcsb pdb:2KRR|reactome:R-HSA-6791226 - - - figure legend:Fig. 5A, Supp. Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells) - 2020/05/21 2021/04/12 rogid:WEdwMYKpu1uQll5NXnMm4P51R4E9606 rogid:PbsEnzoLR4dES5SnMwx08Hr6yeo9606 rigid:1P63pNv1yn3F27gcT2OsGH/3EDQ false green fluorescent protein tag:n-n|mutation disrupting interaction strength:406-406,404-404 - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q8NHP6 uniprotkb:H7BYN3 intact:EBI-2812848|uniprotkb:Q8NA83|uniprotkb:Q8N3H2|ensembl:ENSP00000369860 intact:EBI-25617884|ensembl:ENSP00000378776 psi-mi:mspd2_human(display_long)|uniprotkb:MOSPD2(gene name)|psi-mi:MOSPD2(display_short) psi-mi:h7byn3_human(display_long)|uniprotkb:TFAM(gene name)|psi-mi:TFAM(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Di et al. (2018) pubmed:29858488|imex:IM-28178 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-25617558|imex:IM-28178-11 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001170946.1|refseq:NP_689794.1|go:"GO:0090023"(positive regulation of neutrophil chemotaxis)|go:"GO:0090026"(positive regulation of monocyte chemotaxis)|go:"GO:0140284"(endoplasmic reticulum-endosome membrane contact site)|interpro:IPR000535(Major sperm protein)|interpro:IPR001251(Cellular retinaldehyde-binding/triple function, C-terminal)|interpro:IPR008962(PapD-like)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR036273|interpro:IPR036865|mint:Q8NHP6|rcsb pdb:6TQS|rcsb pdb:6TQT|rcsb pdb:6TQU|reactome:R-HSA-6798695|reactome:R-HSA-9013405|ensembl:ENSG00000130150(gene)|ensembl:ENST00000380492(transcript)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006935"(chemotaxis)|go:"GO:0016020"(membrane)|go:"GO:0035579"(specific granule membrane)|go:"GO:0044232"(organelle membrane contact site) ensembl:ENSG00000108064(gene)|ensembl:ENST00000395377(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005739"(mitochondrion)|interpro:IPR009071(High mobility group box, HMG)|interpro:IPR036910 - - - figure legend:Fig. 5A, Supp. Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells) - 2020/05/21 2021/04/12 rogid:WEdwMYKpu1uQll5NXnMm4P51R4E9606 rogid:UjF2BBH3+KEDkSPOgUh3pSUx4zQ9606 rigid:1P63pNv1yn3F27gcT2OsGH/3EDQ false green fluorescent protein tag:n-n|mutation disrupting interaction strength:406-406,404-404 - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q8NHP6 uniprotkb:Q08211 intact:EBI-2812848|uniprotkb:Q8NA83|uniprotkb:Q8N3H2|ensembl:ENSP00000369860 intact:EBI-352022|intact:EBI-1058470|uniprotkb:Q5VY62|uniprotkb:Q6PD69|uniprotkb:Q99556|uniprotkb:B2RNV4|uniprotkb:Q05CI5|uniprotkb:Q12803|uniprotkb:Q32Q22|ensembl:ENSP00000356520 psi-mi:mspd2_human(display_long)|uniprotkb:MOSPD2(gene name)|psi-mi:MOSPD2(display_short) psi-mi:dhx9_human(display_long)|uniprotkb:DHX9(gene name)|psi-mi:DHX9(display_short)|uniprotkb:DDX9(gene name synonym)|uniprotkb:NDH2(gene name synonym)|uniprotkb:DExH-box helicase 9(gene name synonym)|uniprotkb:RNA helicase A(gene name synonym)|uniprotkb:LKP(gene name synonym)|uniprotkb:Nuclear DNA helicase II(gene name synonym)|uniprotkb:DEAH box protein 9(gene name synonym)|uniprotkb:Leukophysin(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Di et al. (2018) pubmed:29858488|imex:IM-28178 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-25617558|imex:IM-28178-11 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001170946.1|refseq:NP_689794.1|go:"GO:0090023"(positive regulation of neutrophil chemotaxis)|go:"GO:0090026"(positive regulation of monocyte chemotaxis)|go:"GO:0140284"(endoplasmic reticulum-endosome membrane contact site)|interpro:IPR000535(Major sperm protein)|interpro:IPR001251(Cellular retinaldehyde-binding/triple function, C-terminal)|interpro:IPR008962(PapD-like)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR036273|interpro:IPR036865|mint:Q8NHP6|rcsb pdb:6TQS|rcsb pdb:6TQT|rcsb pdb:6TQU|reactome:R-HSA-6798695|reactome:R-HSA-9013405|ensembl:ENSG00000130150(gene)|ensembl:ENST00000380492(transcript)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006935"(chemotaxis)|go:"GO:0016020"(membrane)|go:"GO:0035579"(specific granule membrane)|go:"GO:0044232"(organelle membrane contact site) refseq:NP_001348.2|dip:DIP-31504N|go:"GO:0017111"(nucleoside-triphosphatase activity)|go:"GO:0030423"(targeting of mRNA for destruction involved in RNA interference)|go:"GO:0031490"(chromatin DNA binding)|go:"GO:0032508"(DNA duplex unwinding)|go:"GO:0032727"(positive regulation of interferon-alpha production)|go:"GO:0032728"(positive regulation of interferon-beta production)|go:"GO:0032741"(positive regulation of interleukin-18 production)|go:"GO:0032755"(positive regulation of interleukin-6 production)|go:"GO:0032760"(positive regulation of tumor necrosis factor production)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033679"(3'-5' DNA/RNA helicase activity)|go:"GO:0034458"(3'-5' RNA helicase activity)|go:"GO:0034622"|go:"GO:0035197"(siRNA binding)|go:"GO:0035613"(RNA stem-loop binding)|go:"GO:0036464"(cytoplasmic ribonucleoprotein granule)|go:"GO:0039695"(DNA-templated viral transcription)|go:"GO:0042788"(polysomal ribosome)|go:"GO:0043138"(3'-5' DNA helicase activity)|go:"GO:0044806"(G-quadruplex DNA unwinding)|go:"GO:0045087"(innate immune response)|go:"GO:0045089"(positive regulation of innate immune response)|go:"GO:0045142"(triplex DNA binding)|go:"GO:0045739"(positive regulation of DNA repair)|go:"GO:0045740"(positive regulation of DNA replication)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046833"(positive regulation of RNA export from nucleus)|go:"GO:0046872"(metal ion binding)|go:"GO:0047429"(nucleoside-triphosphate diphosphatase activity)|go:"GO:0048146"(positive regulation of fibroblast proliferation)|go:"GO:0048511"(rhythmic process)|go:"GO:0050434"(positive regulation of viral transcription)|go:"GO:0050684"(regulation of mRNA processing)|go:"GO:0050691"(regulation of defense response to virus by host)|go:"GO:0050729"(positive regulation of inflammatory response)|go:"GO:0051028"(mRNA transport)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|go:"GO:0060760"(positive regulation of response to cytokine stimulus)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:0061676"(importin-alpha family protein binding)|go:"GO:0070063"(RNA polymerase binding)|go:"GO:0070269"(pyroptosis)|go:"GO:0070578"(RISC-loading complex)|go:"GO:0070922"(small RNA loading onto RISC)|go:"GO:0070934"(CRD-mediated mRNA stabilization)|go:"GO:0070937"(CRD-mediated mRNA stability complex)|go:"GO:0071356"(cellular response to tumor necrosis factor)|go:"GO:0071360"(cellular response to exogenous dsRNA)|go:"GO:0097165"(nuclear stress granule)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|go:"GO:1903608"(protein localization to cytoplasmic stress granule)|go:"GO:1905172"(RISC complex binding)|go:"GO:1905538"(polysome binding)|go:"GO:1905698"(positive regulation of polysome binding)|go:"GO:1990518"(single-stranded 3'-5' DNA helicase activity)|go:"GO:1990825"(sequence-specific mRNA binding)|go:"GO:1990841"(promoter-specific chromatin binding)|go:"GO:1990904"(ribonucleoprotein complex)|go:"GO:2000373"("positive regulation of DNA topoisomerase (ATP-hydrolyzing) activity")|go:"GO:2000637"(positive regulation of gene silencing by miRNA)|go:"GO:2000765"(regulation of cytoplasmic translation)|go:"GO:2000767"(positive regulation of cytoplasmic translation)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR002464(DNA/RNA helicase, ATP-dependent, DEAH-box type, conserved site)|interpro:IPR007502(Helicase-associated region)|interpro:IPR011545(DNA/RNA helicase, DEAD/DEAH box type, N-terminal)|interpro:IPR011709(Region of unknown function DUF1605)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR014720(Double-stranded RNA-binding-like)|interpro:IPR027417|interpro:IPR044445|interpro:IPR044446|interpro:IPR044447|mint:Q08211|rcsb pdb:3LLM|rcsb pdb:3VYX|rcsb pdb:3VYY|reactome:R-HSA-1810476|reactome:R-HSA-3134963|reactome:R-HSA-72163|go:"GO:1904973"(positive regulation of viral translation)|ensembl:ENSG00000135829(gene)|ensembl:ENST00000367549(transcript)|go:"GO:0000380"(alternative mRNA splicing, via spliceosome)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000993"(RNA polymerase II complex binding)|go:"GO:0001069"(regulatory region RNA binding)|go:"GO:0001649"(osteoblast differentiation)|go:"GO:0003677"(DNA binding)|go:"GO:0003678"(DNA helicase activity)|go:"GO:0003688"(DNA replication origin binding)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0003723"(RNA binding)|go:"GO:0003724"(RNA helicase activity)|go:"GO:0003725"(double-stranded RNA binding)|go:"GO:0003727"(single-stranded RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005726"(perichromatin fibrils)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005844"(polysome)|go:"GO:0006260"(DNA replication)|go:"GO:0006353"(DNA-templated transcription, termination)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006954"(inflammatory response)|go:"GO:0010501"(RNA secondary structure unwinding)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0016020"(membrane)|go:"GO:0016442"(RISC complex)|go:"GO:0016604"(nuclear body) - - - figure legend:Fig. 5A, Supp. Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells) - 2020/05/21 2021/04/12 rogid:WEdwMYKpu1uQll5NXnMm4P51R4E9606 rogid:b0VP2Frtvwa9WbYVMwB6TbV2uGU9606 rigid:1P63pNv1yn3F27gcT2OsGH/3EDQ false green fluorescent protein tag:n-n|mutation disrupting interaction strength:406-406,404-404 - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q8NHP6 uniprotkb:P02545 intact:EBI-2812848|uniprotkb:Q8NA83|uniprotkb:Q8N3H2|ensembl:ENSP00000369860 intact:EBI-351935|uniprotkb:B4DI32|uniprotkb:E7EUI9|uniprotkb:P02546|uniprotkb:Q969I8|uniprotkb:Q96JA2|uniprotkb:D6RAQ3|uniprotkb:Q5I6Y4|uniprotkb:Q5I6Y6|uniprotkb:Q6UYC3|uniprotkb:Q5TCJ2|uniprotkb:Q5TCJ3|uniprotkb:D3DVB0|intact:EBI-28988787|ensembl:ENSP00000355292|ensembl:ENSP00000357283|ensembl:ENSP00000502256|ensembl:ENSP00000506771 psi-mi:mspd2_human(display_long)|uniprotkb:MOSPD2(gene name)|psi-mi:MOSPD2(display_short) psi-mi:lmna_human(display_long)|uniprotkb:LMNA(gene name)|psi-mi:LMNA(display_short)|uniprotkb:LMN1(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Di et al. (2018) pubmed:29858488|imex:IM-28178 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-25617558|imex:IM-28178-11 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001170946.1|refseq:NP_689794.1|go:"GO:0090023"(positive regulation of neutrophil chemotaxis)|go:"GO:0090026"(positive regulation of monocyte chemotaxis)|go:"GO:0140284"(endoplasmic reticulum-endosome membrane contact site)|interpro:IPR000535(Major sperm protein)|interpro:IPR001251(Cellular retinaldehyde-binding/triple function, C-terminal)|interpro:IPR008962(PapD-like)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR036273|interpro:IPR036865|mint:Q8NHP6|rcsb pdb:6TQS|rcsb pdb:6TQT|rcsb pdb:6TQU|reactome:R-HSA-6798695|reactome:R-HSA-9013405|ensembl:ENSG00000130150(gene)|ensembl:ENST00000380492(transcript)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006935"(chemotaxis)|go:"GO:0016020"(membrane)|go:"GO:0035579"(specific granule membrane)|go:"GO:0044232"(organelle membrane contact site) refseq:NP_005563.1|refseq:NP_733821.1|refseq:NP_733822.1|refseq:NP_001244303.1|refseq:NP_001269553.1|refseq:NP_001269554.1|refseq:NP_001269555.1|ensembl:ENSG00000160789(gene)|ensembl:ENST00000361308(transcript)|ensembl:ENST00000368300(transcript)|ensembl:ENST00000675939(transcript)|ensembl:ENST00000683032(transcript)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005634"(nucleus)|go:"GO:0005638"(lamin filament)|go:"GO:0005652"(nuclear lamina)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005882"(intermediate filament)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0006998"(nuclear envelope organization)|go:"GO:0007517"(muscle organ development)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0016363"(nuclear matrix)|go:"GO:0016604"(nuclear body)|go:"GO:0016607"(nuclear speck)|go:"GO:0030334"(regulation of cell migration)|go:"GO:0030951"(establishment or maintenance of microtubule cytoskeleton polarity)|go:"GO:0031647"(regulation of protein stability)|go:"GO:0031965"(nuclear membrane)|go:"GO:0032204"(regulation of telomere maintenance)|go:"GO:0034504"(protein localization to nucleus)|go:"GO:0005635"(nuclear envelope)|go:"GO:0034613"(cellular protein localization)|go:"GO:0035861"(site of double-strand break)|go:"GO:0042802"(identical protein binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0055015"(ventricular cardiac muscle cell development)|go:"GO:0071456"(cellular response to hypoxia)|go:"GO:0072201"(negative regulation of mesenchymal cell proliferation)|go:"GO:0090201"(negative regulation of release of cytochrome c from mitochondria)|go:"GO:0090343"(positive regulation of cell aging)|go:"GO:1900114"(positive regulation of histone H3-K9 trimethylation)|go:"GO:1900180"(regulation of protein localization to nucleus)|go:"GO:1903243"(negative regulation of cardiac muscle hypertrophy in response to stress)|go:"GO:1990683"(DNA double-strand break attachment to nuclear envelope)|go:"GO:2001237"(negative regulation of extrinsic apoptotic signaling pathway)|interpro:IPR001322(Intermediate filament, C-terminal)|interpro:IPR018039|interpro:IPR036415|interpro:IPR039008|mint:P02545|rcsb pdb:1IFR|rcsb pdb:1IVT|rcsb pdb:1X8Y|rcsb pdb:2XV5|rcsb pdb:2YPT|rcsb pdb:3GEF|rcsb pdb:3V4Q|rcsb pdb:3V4W|rcsb pdb:3V5B|rcsb pdb:6GHD|rcsb pdb:6JLB|rcsb pdb:6RPR|rcsb pdb:6SNZ|rcsb pdb:6YF5|rcsb pdb:6YJD|reactome:R-HSA-1221632|reactome:R-HSA-2980766|reactome:R-HSA-2995383|reactome:R-HSA-352238|reactome:R-HSA-381038|reactome:R-HSA-4419969|reactome:R-HSA-6802952|reactome:R-HSA-8862803|ensembl:ENSP00000503633|ensembl:ENST00000682650|ensembl:ENSP00000506904|ensembl:ENST00000677389|ensembl:ENSP00000506771|ensembl:ENSP00000355292|ensembl:ENST00000368299|ensembl:ENSP00000357282|ensembl:ENSP00000357283|ensembl:ENST00000368301|ensembl:ENSP00000357284|ensembl:ENST00000448611|ensembl:ENSP00000395597|ensembl:ENST00000473598|ensembl:ENSP00000421821|ensembl:ENSP00000502256|ensembl:ENST00000676385|ensembl:ENSP00000502091|dip:DIP-32948N|dip:DIP-58162N - - - figure legend:Fig. 5A, Supp. Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells) - 2020/05/21 2021/04/12 rogid:WEdwMYKpu1uQll5NXnMm4P51R4E9606 rogid:OS/QDFLGOD2PElQ6mCpBtk6xh/09606 rigid:1P63pNv1yn3F27gcT2OsGH/3EDQ false green fluorescent protein tag:n-n|mutation disrupting interaction strength:406-406,404-404 - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q8NHP6 uniprotkb:G5E9W7 intact:EBI-2812848|uniprotkb:Q8NA83|uniprotkb:Q8N3H2|ensembl:ENSP00000369860 intact:EBI-11145876|ensembl:ENSP00000419303 psi-mi:mspd2_human(display_long)|uniprotkb:MOSPD2(gene name)|psi-mi:MOSPD2(display_short) psi-mi:g5e9w7_human(display_long)|uniprotkb:MRPS22(gene name)|psi-mi:MRPS22(display_short)|uniprotkb:hCG_17223(orf name) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Di et al. (2018) pubmed:29858488|imex:IM-28178 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-25617558|imex:IM-28178-11 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001170946.1|refseq:NP_689794.1|go:"GO:0090023"(positive regulation of neutrophil chemotaxis)|go:"GO:0090026"(positive regulation of monocyte chemotaxis)|go:"GO:0140284"(endoplasmic reticulum-endosome membrane contact site)|interpro:IPR000535(Major sperm protein)|interpro:IPR001251(Cellular retinaldehyde-binding/triple function, C-terminal)|interpro:IPR008962(PapD-like)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR036273|interpro:IPR036865|mint:Q8NHP6|rcsb pdb:6TQS|rcsb pdb:6TQT|rcsb pdb:6TQU|reactome:R-HSA-6798695|reactome:R-HSA-9013405|ensembl:ENSG00000130150(gene)|ensembl:ENST00000380492(transcript)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006935"(chemotaxis)|go:"GO:0016020"(membrane)|go:"GO:0035579"(specific granule membrane)|go:"GO:0044232"(organelle membrane contact site) refseq:XP_011511297.1|ensembl:ENSG00000175110(gene)|ensembl:ENST00000478464(transcript)|go:"GO:0005739"(mitochondrion)|go:"GO:0005840"(ribosome)|interpro:IPR019374 - - - figure legend:Fig. 5A, Supp. Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells) - 2020/05/21 2021/04/12 rogid:WEdwMYKpu1uQll5NXnMm4P51R4E9606 rogid:Al6sQb04hHcV9i8eiByySCNFz0o9606 rigid:1P63pNv1yn3F27gcT2OsGH/3EDQ false green fluorescent protein tag:n-n|mutation disrupting interaction strength:406-406,404-404 - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q8NHP6 uniprotkb:H7BYZ9 intact:EBI-2812848|uniprotkb:Q8NA83|uniprotkb:Q8N3H2|ensembl:ENSP00000369860 intact:EBI-25617870|ensembl:ENSP00000385327 psi-mi:mspd2_human(display_long)|uniprotkb:MOSPD2(gene name)|psi-mi:MOSPD2(display_short) psi-mi:h7byz9_human(display_long)|uniprotkb:MTARC1(gene name)|psi-mi:MTARC1(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Di et al. (2018) pubmed:29858488|imex:IM-28178 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-25617558|imex:IM-28178-11 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001170946.1|refseq:NP_689794.1|go:"GO:0090023"(positive regulation of neutrophil chemotaxis)|go:"GO:0090026"(positive regulation of monocyte chemotaxis)|go:"GO:0140284"(endoplasmic reticulum-endosome membrane contact site)|interpro:IPR000535(Major sperm protein)|interpro:IPR001251(Cellular retinaldehyde-binding/triple function, C-terminal)|interpro:IPR008962(PapD-like)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR036273|interpro:IPR036865|mint:Q8NHP6|rcsb pdb:6TQS|rcsb pdb:6TQT|rcsb pdb:6TQU|reactome:R-HSA-6798695|reactome:R-HSA-9013405|ensembl:ENSG00000130150(gene)|ensembl:ENST00000380492(transcript)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006935"(chemotaxis)|go:"GO:0016020"(membrane)|go:"GO:0035579"(specific granule membrane)|go:"GO:0044232"(organelle membrane contact site) ensembl:ENSG00000186205(gene)|ensembl:ENST00000407981(transcript)|go:"GO:0003824"(catalytic activity)|go:"GO:0005739"(mitochondrion)|go:"GO:0030151"(molybdenum ion binding)|go:"GO:0030170"(pyridoxal phosphate binding)|interpro:IPR005302(Molybdenum cofactor sulphurase, C-terminal)|interpro:IPR005303(MOSC, N-terminal beta barrel)|interpro:IPR011037(Pyruvate kinase, beta-barrel-like) - - - figure legend:Fig. 5A, Supp. Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells) - 2020/05/21 2021/04/12 rogid:WEdwMYKpu1uQll5NXnMm4P51R4E9606 rogid:jefJB0CCsdAgroAyzOu5yHxvlkA9606 rigid:1P63pNv1yn3F27gcT2OsGH/3EDQ false green fluorescent protein tag:n-n|mutation disrupting interaction strength:406-406,404-404 - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q8NHP6 uniprotkb:A0A087WXM6 intact:EBI-2812848|uniprotkb:Q8NA83|uniprotkb:Q8N3H2|ensembl:ENSP00000369860 intact:EBI-25617856|ensembl:ENSP00000481145 psi-mi:mspd2_human(display_long)|uniprotkb:MOSPD2(gene name)|psi-mi:MOSPD2(display_short) psi-mi:a0a087wxm6_human(display_long)|uniprotkb:RPL17(gene name)|psi-mi:RPL17(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Di et al. (2018) pubmed:29858488|imex:IM-28178 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-25617558|imex:IM-28178-11 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001170946.1|refseq:NP_689794.1|go:"GO:0090023"(positive regulation of neutrophil chemotaxis)|go:"GO:0090026"(positive regulation of monocyte chemotaxis)|go:"GO:0140284"(endoplasmic reticulum-endosome membrane contact site)|interpro:IPR000535(Major sperm protein)|interpro:IPR001251(Cellular retinaldehyde-binding/triple function, C-terminal)|interpro:IPR008962(PapD-like)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR036273|interpro:IPR036865|mint:Q8NHP6|rcsb pdb:6TQS|rcsb pdb:6TQT|rcsb pdb:6TQU|reactome:R-HSA-6798695|reactome:R-HSA-9013405|ensembl:ENSG00000130150(gene)|ensembl:ENST00000380492(transcript)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006935"(chemotaxis)|go:"GO:0016020"(membrane)|go:"GO:0035579"(specific granule membrane)|go:"GO:0044232"(organelle membrane contact site) ensembl:ENSG00000265681(gene)|ensembl:ENST00000617346(transcript)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0006412"(translation)|go:"GO:0015934"(large ribosomal subunit)|interpro:IPR001063(Ribosomal protein L22/L17)|interpro:IPR005721(Ribosomal protein L22/L17, eukaryotic/archaeal)|interpro:IPR018260|interpro:IPR036394 - - - figure legend:Fig. 5A, Supp. Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells) - 2020/05/21 2021/04/12 rogid:WEdwMYKpu1uQll5NXnMm4P51R4E9606 rogid:Tgr710i14CDeomV1QIuSiTbXQBI9606 rigid:1P63pNv1yn3F27gcT2OsGH/3EDQ false green fluorescent protein tag:n-n|mutation disrupting interaction strength:406-406,404-404 - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q8NHP6 uniprotkb:P60842 intact:EBI-2812848|uniprotkb:Q8NA83|uniprotkb:Q8N3H2|ensembl:ENSP00000369860 intact:EBI-73449|uniprotkb:P04765|uniprotkb:Q5U018|uniprotkb:Q61516|uniprotkb:B2R6L8|uniprotkb:D3DTP9|uniprotkb:J3QLC4|ensembl:ENSP00000293831 psi-mi:mspd2_human(display_long)|uniprotkb:MOSPD2(gene name)|psi-mi:MOSPD2(display_short) psi-mi:if4a1_human(display_long)|uniprotkb:EIF4A1(gene name)|psi-mi:EIF4A1(display_short)|uniprotkb:EIF4A(gene name synonym)|uniprotkb:DDX2A(gene name synonym)|uniprotkb:ATP-dependent RNA helicase eIF4A-1(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Di et al. (2018) pubmed:29858488|imex:IM-28178 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-25617558|imex:IM-28178-11 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001170946.1|refseq:NP_689794.1|go:"GO:0090023"(positive regulation of neutrophil chemotaxis)|go:"GO:0090026"(positive regulation of monocyte chemotaxis)|go:"GO:0140284"(endoplasmic reticulum-endosome membrane contact site)|interpro:IPR000535(Major sperm protein)|interpro:IPR001251(Cellular retinaldehyde-binding/triple function, C-terminal)|interpro:IPR008962(PapD-like)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR036273|interpro:IPR036865|mint:Q8NHP6|rcsb pdb:6TQS|rcsb pdb:6TQT|rcsb pdb:6TQU|reactome:R-HSA-6798695|reactome:R-HSA-9013405|ensembl:ENSG00000130150(gene)|ensembl:ENST00000380492(transcript)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006935"(chemotaxis)|go:"GO:0016020"(membrane)|go:"GO:0035579"(specific granule membrane)|go:"GO:0044232"(organelle membrane contact site) refseq:NP_001407.1|refseq:NP_001191439.1|dip:DIP-29755N|ensembl:ENSG00000161960(gene)|ensembl:ENST00000293831(transcript)|go:"GO:0000339"(RNA cap binding)|go:"GO:0002183"(cytoplasmic translational initiation)|go:"GO:0003723"(RNA binding)|go:"GO:0003724"(RNA helicase activity)|go:"GO:0003725"(double-stranded RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0003743"(translation initiation factor activity)|go:"GO:0004386"(helicase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0008135"(translation factor activity, RNA binding)|go:"GO:0016020"(membrane)|go:"GO:0016281"(eukaryotic translation initiation factor 4F complex)|go:"GO:0070062"(extracellular exosome)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|interpro:IPR000629(RNA helicase, ATP-dependent, DEAD-box, conserved site)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR011545(DNA/RNA helicase, DEAD/DEAH box type, N-terminal)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR014014(RNA helicase, DEAD-box type, Q motif)|interpro:IPR027417|interpro:IPR044728|mint:P60842|rcsb pdb:2G9N|rcsb pdb:2ZU6|rcsb pdb:3EIQ|rcsb pdb:5ZBZ|rcsb pdb:5ZC9|rcsb pdb:6ZMW|reactome:R-HSA-1169408|reactome:R-HSA-156827|reactome:R-HSA-429947|reactome:R-HSA-72649|reactome:R-HSA-72662|reactome:R-HSA-72702|reactome:R-HSA-72706 - - - figure legend:Fig. 5A, Supp. Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells) - 2020/05/21 2021/04/12 rogid:WEdwMYKpu1uQll5NXnMm4P51R4E9606 rogid:e+2gp47oHrpxFbrBFSM4qTf3r7E9606 rigid:1P63pNv1yn3F27gcT2OsGH/3EDQ false green fluorescent protein tag:n-n|mutation disrupting interaction strength:406-406,404-404 - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q8NHP6 uniprotkb:P36578 intact:EBI-2812848|uniprotkb:Q8NA83|uniprotkb:Q8N3H2|ensembl:ENSP00000369860 intact:EBI-348313|ensembl:ENSP00000311430|uniprotkb:P39029|uniprotkb:Q4VBR0|uniprotkb:Q969Z9|uniprotkb:A8K502 psi-mi:mspd2_human(display_long)|uniprotkb:MOSPD2(gene name)|psi-mi:MOSPD2(display_short) psi-mi:rl4_human(display_long)|uniprotkb:RPL4(gene name)|psi-mi:RPL4(display_short)|uniprotkb:RPL1(gene name synonym)|uniprotkb:60S ribosomal protein L1(gene name synonym)|uniprotkb:Large ribosomal subunit protein uL4(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Di et al. (2018) pubmed:29858488|imex:IM-28178 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-25617558|imex:IM-28178-11 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001170946.1|refseq:NP_689794.1|go:"GO:0090023"(positive regulation of neutrophil chemotaxis)|go:"GO:0090026"(positive regulation of monocyte chemotaxis)|go:"GO:0140284"(endoplasmic reticulum-endosome membrane contact site)|interpro:IPR000535(Major sperm protein)|interpro:IPR001251(Cellular retinaldehyde-binding/triple function, C-terminal)|interpro:IPR008962(PapD-like)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR036273|interpro:IPR036865|mint:Q8NHP6|rcsb pdb:6TQS|rcsb pdb:6TQT|rcsb pdb:6TQU|reactome:R-HSA-6798695|reactome:R-HSA-9013405|ensembl:ENSG00000130150(gene)|ensembl:ENST00000380492(transcript)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006935"(chemotaxis)|go:"GO:0016020"(membrane)|go:"GO:0035579"(specific granule membrane)|go:"GO:0044232"(organelle membrane contact site) ensembl:ENSG00000174444(gene)|ensembl:ENST00000307961(transcript)|go:"GO:0002181"(cytoplasmic translation)|go:"GO:0003723"(RNA binding)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005634"(nucleus)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005791"(rough endoplasmic reticulum)|go:"GO:0005829"(cytosol)|go:"GO:0005925"(focal adhesion)|go:"GO:0006412"(translation)|go:"GO:0016020"(membrane)|go:"GO:0022625"(cytosolic large ribosomal subunit)|go:"GO:0022626"(cytosolic ribosome)|go:"GO:0070062"(extracellular exosome)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR002136(Ribosomal protein L4/L1e)|interpro:IPR013000(Ribosomal protein L4/L1e, eukaryotic/archaeal, conserved site)|interpro:IPR025755|mint:P36578|rcsb pdb:4UG0|rcsb pdb:4V6X|rcsb pdb:5A8L|rcsb pdb:5AJ0|rcsb pdb:5LKS|rcsb pdb:5T2C|rcsb pdb:6EK0|rcsb pdb:6IP5|rcsb pdb:6IP6|rcsb pdb:6IP8|rcsb pdb:6LQM|rcsb pdb:6LSR|rcsb pdb:6LSS|rcsb pdb:6LU8|rcsb pdb:6OLE|rcsb pdb:6OLF|rcsb pdb:6OLG|interpro:IPR023574|rcsb pdb:6OLI|rcsb pdb:6OLZ|rcsb pdb:6OM7|rcsb pdb:6QZP|rcsb pdb:6W6L|rcsb pdb:6XA1|rcsb pdb:6Y0G|rcsb pdb:6Y2L|rcsb pdb:6Y57|rcsb pdb:6Y6X|rcsb pdb:6Z6L|rcsb pdb:6Z6M|rcsb pdb:6Z6N|rcsb pdb:6ZM7|rcsb pdb:6ZME|rcsb pdb:6ZMI|rcsb pdb:6ZMO|rcsb pdb:7BHP|reactome:R-HSA-156827|reactome:R-HSA-156902|reactome:R-HSA-1799339|reactome:R-HSA-192823|reactome:R-HSA-2408557|reactome:R-HSA-6791226|reactome:R-HSA-72689|reactome:R-HSA-72706|reactome:R-HSA-72764|reactome:R-HSA-9010553|reactome:R-HSA-9633012|reactome:R-HSA-975956|reactome:R-HSA-975957|rcsb pdb:6OM0|refseq:NP_000959.2|dip:DIP-27559N - - - figure legend:Fig. 5A, Supp. Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells) - 2020/05/21 2021/04/12 rogid:WEdwMYKpu1uQll5NXnMm4P51R4E9606 rogid:34il/jyrW0Dqj0eA8GBFgUk05XU9606 rigid:1P63pNv1yn3F27gcT2OsGH/3EDQ false green fluorescent protein tag:n-n|mutation disrupting interaction strength:406-406,404-404 - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q8NHP6 uniprotkb:O95573 intact:EBI-2812848|uniprotkb:Q8NA83|uniprotkb:Q8N3H2|ensembl:ENSP00000369860 intact:EBI-1190822|uniprotkb:Q60I92|uniprotkb:Q8IUM9|ensembl:ENSP00000350012|ensembl:ENSP00000375918|ensembl:ENSP00000504861|ensembl:ENSP00000504907|ensembl:ENSP00000505400|ensembl:ENSP00000505654|ensembl:ENSP00000505793|ensembl:ENSP00000505856|ensembl:ENSP00000505940|ensembl:ENSP00000506361|ensembl:ENSP00000506468|intact:EBI-21359981 psi-mi:mspd2_human(display_long)|uniprotkb:MOSPD2(gene name)|psi-mi:MOSPD2(display_short) psi-mi:acsl3_human(display_long)|uniprotkb:Long-chain acyl-CoA synthetase 3(gene name synonym)|uniprotkb:ACSL3(gene name)|psi-mi:ACSL3(display_short)|uniprotkb:ACS3(gene name synonym)|uniprotkb:FACL3(gene name synonym)|uniprotkb:LACS3(gene name synonym)|uniprotkb:Arachidonate--CoA ligase(gene name synonym)|uniprotkb:Long-chain-fatty-acid--CoA ligase 3(gene name synonym)|uniprotkb:Medium-chain acyl-CoA ligase Acsl3(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Di et al. (2018) pubmed:29858488|imex:IM-28178 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-25617558|imex:IM-28178-11 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001170946.1|refseq:NP_689794.1|go:"GO:0090023"(positive regulation of neutrophil chemotaxis)|go:"GO:0090026"(positive regulation of monocyte chemotaxis)|go:"GO:0140284"(endoplasmic reticulum-endosome membrane contact site)|interpro:IPR000535(Major sperm protein)|interpro:IPR001251(Cellular retinaldehyde-binding/triple function, C-terminal)|interpro:IPR008962(PapD-like)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR036273|interpro:IPR036865|mint:Q8NHP6|rcsb pdb:6TQS|rcsb pdb:6TQT|rcsb pdb:6TQU|reactome:R-HSA-6798695|reactome:R-HSA-9013405|ensembl:ENSG00000130150(gene)|ensembl:ENST00000380492(transcript)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006935"(chemotaxis)|go:"GO:0016020"(membrane)|go:"GO:0035579"(specific granule membrane)|go:"GO:0044232"(organelle membrane contact site) refseq:NP_004448.2|refseq:NP_976251.1|refseq:XP_016859073.1|ensembl:ENSG00000123983(gene)|ensembl:ENST00000357430(transcript)|ensembl:ENST00000392066(transcript)|ensembl:ENST00000679514(transcript)|ensembl:ENST00000679558(transcript)|ensembl:ENST00000680147(transcript)|ensembl:ENST00000680251(transcript)|ensembl:ENST00000680395(transcript)|ensembl:ENST00000680684(transcript)|ensembl:ENST00000680921(transcript)|ensembl:ENST00000681383(transcript)|ensembl:ENST00000681697(transcript)|go:"GO:0001676"(long-chain fatty acid metabolic process)|go:"GO:0004467"(long-chain fatty acid-CoA ligase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005778"(peroxisomal membrane)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005811"(lipid droplet)|go:"GO:0005886"(plasma membrane)|go:"GO:0006631"(fatty acid metabolic process)|go:"GO:0006633"(fatty acid biosynthetic process)|go:"GO:0007420"(brain development)|go:"GO:0007584"(response to nutrient)|go:"GO:0014070"(response to organic cyclic compound)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0019901"(protein kinase binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030182"(neuron differentiation)|go:"GO:0034379"(very-low-density lipoprotein particle assembly)|go:"GO:0035336"(long-chain fatty-acyl-CoA metabolic process)|go:"GO:0035338"(long-chain fatty-acyl-CoA biosynthetic process)|go:"GO:0042998"(positive regulation of Golgi to plasma membrane protein transport)|go:"GO:0044539"(long-chain fatty acid import into cell)|go:"GO:0047676"(arachidonate-CoA ligase activity)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051047"(positive regulation of secretion)|go:"GO:0090433"(palmitoyl-CoA ligase activity)|go:"GO:2001247"(positive regulation of phosphatidylcholine biosynthetic process)|interpro:IPR000873(AMP-dependent synthetase and ligase)|interpro:IPR020845|mint:O95573|reactome:R-HSA-434313|reactome:R-HSA-75876 - - - figure legend:Fig. 5A, Supp. Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells) - 2020/05/21 2021/04/12 rogid:WEdwMYKpu1uQll5NXnMm4P51R4E9606 rogid:L5tCBPOlL45uh0aUFi4algZQ5nY9606 rigid:1P63pNv1yn3F27gcT2OsGH/3EDQ false green fluorescent protein tag:n-n|mutation disrupting interaction strength:406-406,404-404 - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q8NHP6 uniprotkb:B4DUR8 intact:EBI-2812848|uniprotkb:Q8NA83|uniprotkb:Q8N3H2|ensembl:ENSP00000369860 intact:EBI-25617837|ensembl:ENSP00000431543 psi-mi:mspd2_human(display_long)|uniprotkb:MOSPD2(gene name)|psi-mi:MOSPD2(display_short) psi-mi:b4dur8_human(display_long)|uniprotkb:CCT3(gene name)|psi-mi:CCT3(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Di et al. (2018) pubmed:29858488|imex:IM-28178 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-25617558|imex:IM-28178-11 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001170946.1|refseq:NP_689794.1|go:"GO:0090023"(positive regulation of neutrophil chemotaxis)|go:"GO:0090026"(positive regulation of monocyte chemotaxis)|go:"GO:0140284"(endoplasmic reticulum-endosome membrane contact site)|interpro:IPR000535(Major sperm protein)|interpro:IPR001251(Cellular retinaldehyde-binding/triple function, C-terminal)|interpro:IPR008962(PapD-like)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR036273|interpro:IPR036865|mint:Q8NHP6|rcsb pdb:6TQS|rcsb pdb:6TQT|rcsb pdb:6TQU|reactome:R-HSA-6798695|reactome:R-HSA-9013405|ensembl:ENSG00000130150(gene)|ensembl:ENST00000380492(transcript)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006935"(chemotaxis)|go:"GO:0016020"(membrane)|go:"GO:0035579"(specific granule membrane)|go:"GO:0044232"(organelle membrane contact site) go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0006457"(protein folding)|go:"GO:0051082"(unfolded protein binding)|ensembl:ENST00000472765(transcript)|interpro:IPR002194(Chaperonin TCP-1, conserved site)|interpro:IPR002423(Chaperonin Cpn60/TCP-1)|interpro:IPR012719(T-complex protein 1, gamma subunit)|interpro:IPR017998|interpro:IPR027409|interpro:IPR027410|interpro:IPR027413|ensembl:ENSG00000163468(gene) - - - figure legend:Fig. 5A, Supp. Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells) - 2020/05/21 2021/04/12 rogid:WEdwMYKpu1uQll5NXnMm4P51R4E9606 rogid:FwG3WuUMosnwBELa03i2l++KIWs9606 rigid:1P63pNv1yn3F27gcT2OsGH/3EDQ false green fluorescent protein tag:n-n|mutation disrupting interaction strength:406-406,404-404 - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q8NHP6 uniprotkb:O60506 intact:EBI-2812848|uniprotkb:Q8NA83|uniprotkb:Q8N3H2|ensembl:ENSP00000369860 intact:EBI-1024357|uniprotkb:Q53H05|uniprotkb:Q5TCG2|uniprotkb:Q8IW78|uniprotkb:Q8N599|uniprotkb:Q96LC1|uniprotkb:Q96LC2|uniprotkb:Q9Y583|uniprotkb:Q5TCG3|uniprotkb:E1P501|uniprotkb:E1P502|ensembl:ENSP00000358635|ensembl:ENSP00000503783|ensembl:ENSP00000504706 psi-mi:mspd2_human(display_long)|uniprotkb:MOSPD2(gene name)|psi-mi:MOSPD2(display_short) psi-mi:hnrpq_human(display_long)|uniprotkb:Synaptotagmin-binding, cytoplasmic RNA-interacting protein(gene name synonym)|uniprotkb:Glycine- and tyrosine-rich RNA-binding protein(gene name synonym)|uniprotkb:NS1-associated protein 1(gene name synonym)|uniprotkb:SYNCRIP(gene name)|psi-mi:SYNCRIP(display_short)|uniprotkb:HNRPQ(gene name synonym)|uniprotkb:NSAP1(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Di et al. (2018) pubmed:29858488|imex:IM-28178 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-25617558|imex:IM-28178-11 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001170946.1|refseq:NP_689794.1|go:"GO:0090023"(positive regulation of neutrophil chemotaxis)|go:"GO:0090026"(positive regulation of monocyte chemotaxis)|go:"GO:0140284"(endoplasmic reticulum-endosome membrane contact site)|interpro:IPR000535(Major sperm protein)|interpro:IPR001251(Cellular retinaldehyde-binding/triple function, C-terminal)|interpro:IPR008962(PapD-like)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR036273|interpro:IPR036865|mint:Q8NHP6|rcsb pdb:6TQS|rcsb pdb:6TQT|rcsb pdb:6TQU|reactome:R-HSA-6798695|reactome:R-HSA-9013405|ensembl:ENSG00000130150(gene)|ensembl:ENST00000380492(transcript)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006935"(chemotaxis)|go:"GO:0016020"(membrane)|go:"GO:0035579"(specific granule membrane)|go:"GO:0044232"(organelle membrane contact site) refseq:NP_001153145.1|refseq:NP_001153146.1|refseq:NP_001153147.1|refseq:NP_001240700.1|refseq:NP_001153148.1|refseq:NP_001153149.1|refseq:NP_006363.4|ensembl:ENSG00000135316(gene)|ensembl:ENST00000369622(transcript)|ensembl:ENST00000676688(transcript)|ensembl:ENST00000678355(transcript)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0001649"(osteoblast differentiation)|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0006396"(RNA processing)|go:"GO:0008380"(RNA splicing)|go:"GO:0016020"(membrane)|go:"GO:0017148"(negative regulation of translation)|go:"GO:0048027"(mRNA 5'-UTR binding)|go:"GO:0070934"(CRD-mediated mRNA stabilization)|go:"GO:0070937"(CRD-mediated mRNA stability complex)|go:"GO:0071013"(catalytic step 2 spliceosome)|go:"GO:0071204"(histone pre-mRNA 3'end processing complex)|go:"GO:0071346"(cellular response to interferon-gamma)|go:"GO:0097452"(GAIT complex)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR006535(HnRNP R and Q splicing factor)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR034544|interpro:IPR034548|interpro:IPR035979|interpro:IPR041337|mint:O60506|rcsb pdb:2DGU|rcsb pdb:2MXT|rcsb pdb:2NBB|rcsb pdb:6KOR|refseq:XP_016865667.1|refseq:XP_005248694.1|dip:DIP-35540N - - - figure legend:Fig. 5A, Supp. Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells) - 2020/05/21 2021/04/12 rogid:WEdwMYKpu1uQll5NXnMm4P51R4E9606 rogid:2rDkXIp/wWzTOoVtN7Bd3uqZo689606 rigid:1P63pNv1yn3F27gcT2OsGH/3EDQ false green fluorescent protein tag:n-n|mutation disrupting interaction strength:406-406,404-404 - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q8NHP6 uniprotkb:Q15042 intact:EBI-2812848|uniprotkb:Q8NA83|uniprotkb:Q8N3H2|ensembl:ENSP00000369860 intact:EBI-1053078|uniprotkb:Q659F5|uniprotkb:Q8TBB4|uniprotkb:C9J837|ensembl:ENSP00000264158|uniprotkb:A6H8Z3 psi-mi:mspd2_human(display_long)|uniprotkb:MOSPD2(gene name)|psi-mi:MOSPD2(display_short) psi-mi:rb3gp_human(display_long)|uniprotkb:RAB3 GTPase-activating protein 130 kDa subunit(gene name synonym)|uniprotkb:Rab3-GAP p130(gene name synonym)|uniprotkb:RAB3GAP1(gene name)|psi-mi:RAB3GAP1(display_short)|uniprotkb:KIAA0066(gene name synonym)|uniprotkb:RAB3GAP(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Di et al. (2018) pubmed:29858488|imex:IM-28178 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-25617558|imex:IM-28178-11 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001170946.1|refseq:NP_689794.1|go:"GO:0090023"(positive regulation of neutrophil chemotaxis)|go:"GO:0090026"(positive regulation of monocyte chemotaxis)|go:"GO:0140284"(endoplasmic reticulum-endosome membrane contact site)|interpro:IPR000535(Major sperm protein)|interpro:IPR001251(Cellular retinaldehyde-binding/triple function, C-terminal)|interpro:IPR008962(PapD-like)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR036273|interpro:IPR036865|mint:Q8NHP6|rcsb pdb:6TQS|rcsb pdb:6TQT|rcsb pdb:6TQU|reactome:R-HSA-6798695|reactome:R-HSA-9013405|ensembl:ENSG00000130150(gene)|ensembl:ENST00000380492(transcript)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006935"(chemotaxis)|go:"GO:0016020"(membrane)|go:"GO:0035579"(specific granule membrane)|go:"GO:0044232"(organelle membrane contact site) refseq:NP_036365.1|ensembl:ENSG00000115839(gene)|ensembl:ENST00000264158(transcript)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005811"(lipid droplet)|go:"GO:0005829"(cytosol)|go:"GO:0007420"(brain development)|go:"GO:0021854"(hypothalamus development)|go:"GO:0031267"(small GTPase binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034389"(lipid droplet organization)|go:"GO:0043010"(camera-type eye development)|go:"GO:0043087"(regulation of GTPase activity)|go:"GO:0043547"(positive regulation of GTPase activity)|go:"GO:0048172"(regulation of short-term neuronal synaptic plasticity)|go:"GO:0060079"(excitatory postsynaptic potential)|go:"GO:0060325"(face morphogenesis)|go:"GO:0061646"(positive regulation of glutamate neurotransmitter secretion in response to membrane depolarization)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071782"(endoplasmic reticulum tubular network)|go:"GO:0097051"(establishment of protein localization to endoplasmic reticulum membrane)|go:"GO:0098794"(postsynapse)|go:"GO:1903061"(positive regulation of protein lipidation)|go:"GO:1903233"(regulation of calcium ion-dependent exocytosis of neurotransmitter)|go:"GO:1903373"(positive regulation of endoplasmic reticulum tubular network organization)|go:"GO:2000786"(positive regulation of autophagosome assembly)|interpro:IPR026147|reactome:R-HSA-6811436|reactome:R-HSA-8876198|refseq:NP_001165906.1 - - - figure legend:Fig. 5A, Supp. Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells) - 2020/05/21 2021/04/12 rogid:WEdwMYKpu1uQll5NXnMm4P51R4E9606 rogid:JCtnJX01timbIenQexwG84yBu2I9606 rigid:1P63pNv1yn3F27gcT2OsGH/3EDQ false green fluorescent protein tag:n-n|mutation disrupting interaction strength:406-406,404-404 - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q8NHP6 uniprotkb:P49848 intact:EBI-2812848|uniprotkb:Q8NA83|uniprotkb:Q8N3H2|ensembl:ENSP00000369860 intact:EBI-1560206|uniprotkb:A4D2B2|uniprotkb:A4D2B3|uniprotkb:Q6AI29|uniprotkb:D6W5U2|uniprotkb:B4DT11|ensembl:ENSP00000344537|ensembl:ENSP00000389575|ensembl:ENSP00000416396 psi-mi:mspd2_human(display_long)|uniprotkb:MOSPD2(gene name)|psi-mi:MOSPD2(display_short) psi-mi:taf6_human(display_long)|uniprotkb:Transcription initiation factor TFIID 70 kDa subunit(gene name synonym)|uniprotkb:Transcription initiation factor TFIID 80 kDa subunit(gene name synonym)|uniprotkb:RNA polymerase II TBP-associated factor subunit E(gene name synonym)|uniprotkb:TAF6(gene name)|psi-mi:TAF6(display_short)|uniprotkb:TAF2E(gene name synonym)|uniprotkb:TAFII70(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Di et al. (2018) pubmed:29858488|imex:IM-28178 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-25617558|imex:IM-28178-11 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001170946.1|refseq:NP_689794.1|go:"GO:0090023"(positive regulation of neutrophil chemotaxis)|go:"GO:0090026"(positive regulation of monocyte chemotaxis)|go:"GO:0140284"(endoplasmic reticulum-endosome membrane contact site)|interpro:IPR000535(Major sperm protein)|interpro:IPR001251(Cellular retinaldehyde-binding/triple function, C-terminal)|interpro:IPR008962(PapD-like)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR036273|interpro:IPR036865|mint:Q8NHP6|rcsb pdb:6TQS|rcsb pdb:6TQT|rcsb pdb:6TQU|reactome:R-HSA-6798695|reactome:R-HSA-9013405|ensembl:ENSG00000130150(gene)|ensembl:ENST00000380492(transcript)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006935"(chemotaxis)|go:"GO:0016020"(membrane)|go:"GO:0035579"(specific granule membrane)|go:"GO:0044232"(organelle membrane contact site) refseq:XP_006716163.1|refseq:NP_005632.1|refseq:NP_647476.1|refseq:NP_001177344.1|dip:DIP-773N|ensembl:ENSG00000106290(gene)|ensembl:ENST00000344095(transcript)|ensembl:ENST00000452041(transcript)|go:"GO:0000124"(SAGA complex)|go:"GO:0003677"(DNA binding)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005669"(transcription factor TFIID complex)|go:"GO:0005829"(cytosol)|go:"GO:0006352"(DNA-templated transcription, initiation)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0006367"(transcription initiation from RNA polymerase II promoter)|go:"GO:0006915"(apoptotic process)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0016251"(RNA polymerase II general transcription initiation factor activity)|go:"GO:0016573"(histone acetylation)|go:"GO:0017162"(aryl hydrocarbon receptor binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033276"(transcription factor TFTC complex)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0045786"(negative regulation of cell cycle)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046695"("SLIK (SAGA-like) complex")|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0060261"(positive regulation of transcription initiation from RNA polymerase II promoter)|go:"GO:0071339"(MLL1 complex)|go:"GO:2001244"(positive regulation of intrinsic apoptotic signaling pathway)|interpro:IPR004823("TATA box binding protein associated factor (TAF)")|interpro:IPR009072(Histone-fold)|interpro:IPR011442(Protein of unknown function DUF1546)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR037796|rcsb pdb:5FUR|rcsb pdb:6F3T|rcsb pdb:6MZC|rcsb pdb:6MZD|rcsb pdb:6MZL|rcsb pdb:6MZM|rcsb pdb:7EDX|rcsb pdb:7EG7|rcsb pdb:7EG8|rcsb pdb:7EG9|rcsb pdb:7EGA|rcsb pdb:7EGB|rcsb pdb:7EGC|rcsb pdb:7EGD|rcsb pdb:7EGE|rcsb pdb:7EGF|rcsb pdb:7EGG|rcsb pdb:7EGH|rcsb pdb:7EGI|rcsb pdb:7EGJ|rcsb pdb:7ENA|rcsb pdb:7ENC|reactome:R-HSA-167161|reactome:R-HSA-167162|reactome:R-HSA-167172|reactome:R-HSA-674695|reactome:R-HSA-6804756|reactome:R-HSA-6807505|reactome:R-HSA-73776|reactome:R-HSA-73779|reactome:R-HSA-75953|reactome:R-HSA-76042|ensembl:ENST00000453269(transcript) - - - figure legend:Fig. 5A, Supp. Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells) - 2020/05/21 2021/04/12 rogid:WEdwMYKpu1uQll5NXnMm4P51R4E9606 rogid:oGsdH9+tG2BXsR+jr7hBuCCAS809606 rigid:1P63pNv1yn3F27gcT2OsGH/3EDQ false green fluorescent protein tag:n-n|mutation disrupting interaction strength:406-406,404-404 - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q8NHP6 uniprotkb:H0YEN5 intact:EBI-2812848|uniprotkb:Q8NA83|uniprotkb:Q8N3H2|ensembl:ENSP00000369860 intact:EBI-25617786|ensembl:ENSP00000436227 psi-mi:mspd2_human(display_long)|uniprotkb:MOSPD2(gene name)|psi-mi:MOSPD2(display_short) psi-mi:h0yen5_human(display_long)|uniprotkb:RPS2(gene name)|psi-mi:RPS2(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Di et al. (2018) pubmed:29858488|imex:IM-28178 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-25617558|imex:IM-28178-11 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001170946.1|refseq:NP_689794.1|go:"GO:0090023"(positive regulation of neutrophil chemotaxis)|go:"GO:0090026"(positive regulation of monocyte chemotaxis)|go:"GO:0140284"(endoplasmic reticulum-endosome membrane contact site)|interpro:IPR000535(Major sperm protein)|interpro:IPR001251(Cellular retinaldehyde-binding/triple function, C-terminal)|interpro:IPR008962(PapD-like)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR036273|interpro:IPR036865|mint:Q8NHP6|rcsb pdb:6TQS|rcsb pdb:6TQT|rcsb pdb:6TQU|reactome:R-HSA-6798695|reactome:R-HSA-9013405|ensembl:ENSG00000130150(gene)|ensembl:ENST00000380492(transcript)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006935"(chemotaxis)|go:"GO:0016020"(membrane)|go:"GO:0035579"(specific granule membrane)|go:"GO:0044232"(organelle membrane contact site) ensembl:ENST00000533186(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0006412"(translation)|go:"GO:0015935"(small ribosomal subunit)|interpro:IPR000851(Ribosomal protein S5)|interpro:IPR005324(Ribosomal protein S5, C-terminal)|interpro:IPR005711(Ribosomal protein S5, eukaryotic/archaeal)|interpro:IPR013810(Ribosomal protein S5, N-terminal)|ensembl:ENSG00000140988(gene)|interpro:IPR014721(Ribosomal protein S5 domain 2-type fold)|interpro:IPR020568 - - - figure legend:Fig. 5A, Supp. Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells) - 2020/05/21 2021/04/12 rogid:WEdwMYKpu1uQll5NXnMm4P51R4E9606 rogid:bRUwc0kgSyPXyeZ1UjE0Nmio/x09606 rigid:1P63pNv1yn3F27gcT2OsGH/3EDQ false green fluorescent protein tag:n-n|mutation disrupting interaction strength:406-406,404-404 - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q8NHP6 uniprotkb:Q92841 intact:EBI-2812848|uniprotkb:Q8NA83|uniprotkb:Q8N3H2|ensembl:ENSP00000369860 intact:EBI-746012|uniprotkb:Q69YT1|uniprotkb:Q6ICD6|uniprotkb:H3BLZ8|uniprotkb:B1AHM0|ensembl:ENSP00000385536 psi-mi:mspd2_human(display_long)|uniprotkb:MOSPD2(gene name)|psi-mi:MOSPD2(display_short) psi-mi:ddx17_human(display_long)|uniprotkb:DEAD box protein 17(gene name synonym)|uniprotkb:RNA-dependent helicase p72(gene name synonym)|uniprotkb:DEAD box protein p72(gene name synonym)|uniprotkb:DDX17(gene name)|psi-mi:DDX17(display_short)|uniprotkb:DEAD box protein p82(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Di et al. (2018) pubmed:29858488|imex:IM-28178 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-25617558|imex:IM-28178-11 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001170946.1|refseq:NP_689794.1|go:"GO:0090023"(positive regulation of neutrophil chemotaxis)|go:"GO:0090026"(positive regulation of monocyte chemotaxis)|go:"GO:0140284"(endoplasmic reticulum-endosome membrane contact site)|interpro:IPR000535(Major sperm protein)|interpro:IPR001251(Cellular retinaldehyde-binding/triple function, C-terminal)|interpro:IPR008962(PapD-like)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR036273|interpro:IPR036865|mint:Q8NHP6|rcsb pdb:6TQS|rcsb pdb:6TQT|rcsb pdb:6TQU|reactome:R-HSA-6798695|reactome:R-HSA-9013405|ensembl:ENSG00000130150(gene)|ensembl:ENST00000380492(transcript)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006935"(chemotaxis)|go:"GO:0016020"(membrane)|go:"GO:0035579"(specific granule membrane)|go:"GO:0044232"(organelle membrane contact site) refseq:NP_006377.2|ensembl:ENSG00000100201(gene)|ensembl:ENST00000403230(transcript)|go:"GO:0000380"(alternative mRNA splicing, via spliceosome)|go:"GO:0000381"(regulation of alternative mRNA splicing, via spliceosome)|go:"GO:0001837"(epithelial to mesenchymal transition)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0003723"(RNA binding)|go:"GO:0003724"(RNA helicase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006364"(rRNA processing)|go:"GO:0006396"(RNA processing)|go:"GO:0008186"(ATP-dependent activity, acting on RNA)|go:"GO:0010586"(miRNA metabolic process)|go:"GO:0016020"(membrane)|go:"GO:0016607"(nuclear speck)|go:"GO:0030520"(intracellular estrogen receptor signaling pathway)|go:"GO:0030521"(androgen receptor signaling pathway)|go:"GO:0031047"(gene silencing by RNA)|go:"GO:0045445"(myoblast differentiation)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0051607"(defense response to virus)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|go:"GO:1990904"(ribonucleoprotein complex)|go:"GO:2001014"(regulation of skeletal muscle cell differentiation)|interpro:IPR000629(RNA helicase, ATP-dependent, DEAD-box, conserved site)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR011545(DNA/RNA helicase, DEAD/DEAH box type, N-terminal)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR014014(RNA helicase, DEAD-box type, Q motif)|interpro:IPR027417|mint:Q92841|rcsb pdb:6UV0|rcsb pdb:6UV1|rcsb pdb:6UV2|rcsb pdb:6UV3|rcsb pdb:6UV4|reactome:R-HSA-3899300|dip:DIP-29843N - - - figure legend:Fig. 5A, Supp. Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells) - 2020/05/21 2021/04/12 rogid:WEdwMYKpu1uQll5NXnMm4P51R4E9606 rogid:3UhUuhRSZg/zlM7UPDKYCqNmUho9606 rigid:1P63pNv1yn3F27gcT2OsGH/3EDQ false green fluorescent protein tag:n-n|mutation disrupting interaction strength:406-406,404-404 - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q8NHP6 uniprotkb:P62829 intact:EBI-2812848|uniprotkb:Q8NA83|uniprotkb:Q8N3H2|ensembl:ENSP00000369860 intact:EBI-353303|uniprotkb:P23131|uniprotkb:Q3SWV7|uniprotkb:P24048|uniprotkb:Q29246|uniprotkb:Q6P5S1|ensembl:ENSP00000377865|ensembl:ENSP00000420311 psi-mi:mspd2_human(display_long)|uniprotkb:MOSPD2(gene name)|psi-mi:MOSPD2(display_short) psi-mi:rl23_human(display_long)|uniprotkb:RPL23(gene name)|psi-mi:RPL23(display_short)|uniprotkb:60S ribosomal protein L17(gene name synonym)|uniprotkb:Large ribosomal subunit protein uL14(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Di et al. (2018) pubmed:29858488|imex:IM-28178 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-25617558|imex:IM-28178-11 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001170946.1|refseq:NP_689794.1|go:"GO:0090023"(positive regulation of neutrophil chemotaxis)|go:"GO:0090026"(positive regulation of monocyte chemotaxis)|go:"GO:0140284"(endoplasmic reticulum-endosome membrane contact site)|interpro:IPR000535(Major sperm protein)|interpro:IPR001251(Cellular retinaldehyde-binding/triple function, C-terminal)|interpro:IPR008962(PapD-like)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR036273|interpro:IPR036865|mint:Q8NHP6|rcsb pdb:6TQS|rcsb pdb:6TQT|rcsb pdb:6TQU|reactome:R-HSA-6798695|reactome:R-HSA-9013405|ensembl:ENSG00000130150(gene)|ensembl:ENST00000380492(transcript)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006935"(chemotaxis)|go:"GO:0016020"(membrane)|go:"GO:0035579"(specific granule membrane)|go:"GO:0044232"(organelle membrane contact site) rcsb pdb:6IP8|rcsb pdb:6LQM|rcsb pdb:6LSR|rcsb pdb:6LSS|rcsb pdb:6LU8|rcsb pdb:6OLE|rcsb pdb:6OLF|rcsb pdb:6OLG|rcsb pdb:6OLI|rcsb pdb:6OLZ|rcsb pdb:6OM0|rcsb pdb:6OM7|rcsb pdb:6QZP|rcsb pdb:6XA1|rcsb pdb:6Y0G|rcsb pdb:6Y2L|reactome:R-HSA-9633012|reactome:R-HSA-975956|reactome:R-HSA-975957|rcsb pdb:6Y57|rcsb pdb:6Y6X|rcsb pdb:6Z6L|rcsb pdb:6Z6M|rcsb pdb:6Z6N|rcsb pdb:6ZM7|rcsb pdb:6ZME|reactome:R-HSA-9010553|rcsb pdb:6ZMI|rcsb pdb:6ZMO|reactome:R-HSA-156827|reactome:R-HSA-156902|reactome:R-HSA-1799339|reactome:R-HSA-192823|reactome:R-HSA-2408557|reactome:R-HSA-6791226|reactome:R-HSA-72689|reactome:R-HSA-72706|reactome:R-HSA-72764|refseq:NP_000969.1|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0014069"(postsynaptic density)|go:"GO:0016020"(membrane)|go:"GO:0022625"(cytosolic large ribosomal subunit)|go:"GO:0022626"(cytosolic ribosome)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032986"(protein-DNA complex disassembly)|go:"GO:0032991"(protein-containing complex)|go:"GO:0050821"(protein stabilization)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070180"(large ribosomal subunit rRNA binding)|go:"GO:0072717"(cellular response to actinomycin D)|go:"GO:1901798"(positive regulation of signal transduction by p53 class mediator)|go:"GO:1904667"(negative regulation of ubiquitin protein ligase activity)|go:"GO:1990948"(ubiquitin ligase inhibitor activity)|go:"GO:2000059"(negative regulation of ubiquitin-dependent protein catabolic process)|interpro:IPR000218(Ribosomal protein L14b/L23e)|interpro:IPR019972|interpro:IPR036853|mint:P62829|rcsb pdb:4UG0|rcsb pdb:4V6X|rcsb pdb:5AJ0|rcsb pdb:5LKS|rcsb pdb:5T2C|rcsb pdb:6EK0|rcsb pdb:6IP5|rcsb pdb:6IP6|ensembl:ENSG00000125691(gene)|ensembl:ENST00000394332(transcript)|ensembl:ENST00000479035(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0001223"(transcription coactivator binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005840"(ribosome)|go:"GO:0005925"(focal adhesion)|go:"GO:0006412"(translation)|go:"GO:0006610"(ribosomal protein import into nucleus)|go:"GO:0002181"(cytoplasmic translation)|go:"GO:0003723"(RNA binding)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005654"(nucleoplasm)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0005730"(nucleolus)|dip:DIP-33156N - - - figure legend:Fig. 5A, Supp. Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells) - 2020/05/21 2021/04/12 rogid:WEdwMYKpu1uQll5NXnMm4P51R4E9606 rogid:TiSVU2W4+lkwf12eb4+vG6IFlZA9606 rigid:1P63pNv1yn3F27gcT2OsGH/3EDQ false green fluorescent protein tag:n-n|mutation disrupting interaction strength:406-406,404-404 - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q8NHP6 uniprotkb:O43752 intact:EBI-2812848|uniprotkb:Q8NA83|uniprotkb:Q8N3H2|ensembl:ENSP00000369860 intact:EBI-2695795|uniprotkb:Q5VY08|uniprotkb:B2R652|uniprotkb:Q6FH83|intact:EBI-28977663|ensembl:ENSP00000258301|uniprotkb:B4DR17 psi-mi:mspd2_human(display_long)|uniprotkb:MOSPD2(gene name)|psi-mi:MOSPD2(display_short) psi-mi:stx6_human(display_long)|uniprotkb:STX6(gene name)|psi-mi:STX6(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Di et al. (2018) pubmed:29858488|imex:IM-28178 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-25617558|imex:IM-28178-11 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001170946.1|refseq:NP_689794.1|go:"GO:0090023"(positive regulation of neutrophil chemotaxis)|go:"GO:0090026"(positive regulation of monocyte chemotaxis)|go:"GO:0140284"(endoplasmic reticulum-endosome membrane contact site)|interpro:IPR000535(Major sperm protein)|interpro:IPR001251(Cellular retinaldehyde-binding/triple function, C-terminal)|interpro:IPR008962(PapD-like)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR036273|interpro:IPR036865|mint:Q8NHP6|rcsb pdb:6TQS|rcsb pdb:6TQT|rcsb pdb:6TQU|reactome:R-HSA-6798695|reactome:R-HSA-9013405|ensembl:ENSG00000130150(gene)|ensembl:ENST00000380492(transcript)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006935"(chemotaxis)|go:"GO:0016020"(membrane)|go:"GO:0035579"(specific granule membrane)|go:"GO:0044232"(organelle membrane contact site) ensembl:ENSP00000258301|ensembl:ENST00000542060|ensembl:ENSP00000440188|refseq:NP_005810.1|ensembl:ENSG00000135823(gene)|ensembl:ENST00000258301(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0000149"(SNARE binding)|go:"GO:0005484"(SNAP receptor activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005769"(early endosome)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006906"(vesicle fusion)|go:"GO:0012505"(endomembrane system)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016189"(synaptic vesicle to endosome fusion)|go:"GO:0019905"(syntaxin binding)|go:"GO:0030136"(clathrin-coated vesicle)|go:"GO:0030285"(integral component of synaptic vesicle membrane)|go:"GO:0031201"(SNARE complex)|go:"GO:0032456"(endocytic recycling)|go:"GO:0032588"(trans-Golgi network membrane)|go:"GO:0032880"(regulation of protein localization)|go:"GO:0042147"(retrograde transport, endosome to Golgi)|go:"GO:0045335"(phagocytic vesicle)|go:"GO:0048193"(Golgi vesicle transport)|go:"GO:0048278"(vesicle docking)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0090161"(Golgi ribbon formation)|go:"GO:1903827"|interpro:IPR000727(Target SNARE coiled-coil region)|interpro:IPR006012(Syntaxin/epimorphin, conserved site)|interpro:IPR010989(t-SNARE)|interpro:IPR015260(Syntaxin 6, N-terminal)|mint:O43752|rcsb pdb:2NPS|rcsb pdb:4J2C|reactome:R-HSA-6811438|reactome:R-HSA-6811440|refseq:NP_001273139.1|refseq:XP_016855496.1|dip:DIP-44224N - - - figure legend:Fig. 5A, Supp. Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells) - 2020/05/21 2021/04/12 rogid:WEdwMYKpu1uQll5NXnMm4P51R4E9606 rogid:g8/HcXvvEY2Pqv8NWy3V+T+jBTY9606 rigid:1P63pNv1yn3F27gcT2OsGH/3EDQ false green fluorescent protein tag:n-n|mutation disrupting interaction strength:406-406,404-404 - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q8NHP6 uniprotkb:Q15717 intact:EBI-2812848|uniprotkb:Q8NA83|uniprotkb:Q8N3H2|ensembl:ENSP00000369860 intact:EBI-374260|uniprotkb:Q9BTT1|ensembl:ENSP00000385269|ensembl:ENSP00000472197|intact:EBI-6190219|uniprotkb:B4DVB8|uniprotkb:Q53XN6 psi-mi:mspd2_human(display_long)|uniprotkb:MOSPD2(gene name)|psi-mi:MOSPD2(display_short) psi-mi:elav1_human(display_long)|uniprotkb:ELAVL1(gene name)|psi-mi:ELAVL1(display_short)|uniprotkb:HUR(gene name synonym)|uniprotkb:Hu-antigen R(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Di et al. (2018) pubmed:29858488|imex:IM-28178 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-25617558|imex:IM-28178-11 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001170946.1|refseq:NP_689794.1|go:"GO:0090023"(positive regulation of neutrophil chemotaxis)|go:"GO:0090026"(positive regulation of monocyte chemotaxis)|go:"GO:0140284"(endoplasmic reticulum-endosome membrane contact site)|interpro:IPR000535(Major sperm protein)|interpro:IPR001251(Cellular retinaldehyde-binding/triple function, C-terminal)|interpro:IPR008962(PapD-like)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR036273|interpro:IPR036865|mint:Q8NHP6|rcsb pdb:6TQS|rcsb pdb:6TQT|rcsb pdb:6TQU|reactome:R-HSA-6798695|reactome:R-HSA-9013405|ensembl:ENSG00000130150(gene)|ensembl:ENST00000380492(transcript)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006935"(chemotaxis)|go:"GO:0016020"(membrane)|go:"GO:0035579"(specific granule membrane)|go:"GO:0044232"(organelle membrane contact site) go:"GO:0006606"(protein import into nucleus)|go:"GO:0010494"(cytoplasmic stress granule)|go:"GO:0016020"(membrane)|go:"GO:0016441"(posttranscriptional gene silencing)|go:"GO:0019901"(protein kinase binding)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0035198"(miRNA binding)|go:"GO:0035925"(mRNA 3'-UTR AU-rich region binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0045727"(positive regulation of translation)|go:"GO:0048255"(mRNA stabilization)|go:"GO:0051260"(protein homooligomerization)|go:"GO:0060965"(negative regulation of gene silencing by miRNA)|go:"GO:0070935"(3'-UTR-mediated mRNA stabilization)|go:"GO:0098794"(postsynapse)|go:"GO:0098978"(glutamatergic synapse)|ensembl:ENSG00000066044(gene)|ensembl:ENST00000407627(transcript)|ensembl:ENST00000596459(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0003725"(double-stranded RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0003730"(mRNA 3'-UTR binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005829"(cytosol)|refseq:NP_001410.2|go:"GO:1990904"(ribonucleoprotein complex)|go:"GO:2000036"(regulation of stem cell population maintenance)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR002343(Paraneoplastic encephalomyelitis antigen)|interpro:IPR006548(Splicing factor ELAV/HuD)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR034775|interpro:IPR034996|interpro:IPR035979|mint:Q15717|rcsb pdb:3HI9|rcsb pdb:4ED5|rcsb pdb:4EGL|rcsb pdb:4FXV|rcsb pdb:5SZW|rcsb pdb:6G2K|rcsb pdb:6GC5|rcsb pdb:6GD1|rcsb pdb:6GD2|rcsb pdb:6GD3|reactome:R-HSA-450520|reactome:R-HSA-72163|dip:DIP-31291N - - - figure legend:Fig. 5A, Supp. Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells) - 2020/05/21 2021/04/12 rogid:WEdwMYKpu1uQll5NXnMm4P51R4E9606 rogid:PciL5KuvP+2aUUv9cv7gWScgbw89606 rigid:1P63pNv1yn3F27gcT2OsGH/3EDQ false green fluorescent protein tag:n-n|mutation disrupting interaction strength:406-406,404-404 - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q8NHP6 uniprotkb:P33993 intact:EBI-2812848|uniprotkb:Q8NA83|uniprotkb:Q8N3H2|ensembl:ENSP00000369860 intact:EBI-355924|uniprotkb:Q15076|uniprotkb:Q96D34|uniprotkb:Q96GL1|uniprotkb:A4D2A1|uniprotkb:A4D2A2|uniprotkb:E9PGN9|ensembl:ENSP00000307288 psi-mi:mspd2_human(display_long)|uniprotkb:MOSPD2(gene name)|psi-mi:MOSPD2(display_short) psi-mi:mcm7_human(display_long)|uniprotkb:MCM7(gene name)|psi-mi:MCM7(display_short)|uniprotkb:CDC47(gene name synonym)|uniprotkb:MCM2(gene name synonym)|uniprotkb:CDC47 homolog(gene name synonym)|uniprotkb:P1.1-MCM3(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Di et al. (2018) pubmed:29858488|imex:IM-28178 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-25617558|imex:IM-28178-11 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001170946.1|refseq:NP_689794.1|go:"GO:0090023"(positive regulation of neutrophil chemotaxis)|go:"GO:0090026"(positive regulation of monocyte chemotaxis)|go:"GO:0140284"(endoplasmic reticulum-endosome membrane contact site)|interpro:IPR000535(Major sperm protein)|interpro:IPR001251(Cellular retinaldehyde-binding/triple function, C-terminal)|interpro:IPR008962(PapD-like)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR036273|interpro:IPR036865|mint:Q8NHP6|rcsb pdb:6TQS|rcsb pdb:6TQT|rcsb pdb:6TQU|reactome:R-HSA-6798695|reactome:R-HSA-9013405|ensembl:ENSG00000130150(gene)|ensembl:ENST00000380492(transcript)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006935"(chemotaxis)|go:"GO:0016020"(membrane)|go:"GO:0035579"(specific granule membrane)|go:"GO:0044232"(organelle membrane contact site) refseq:NP_001265524.1|refseq:NP_005907.3|refseq:NP_877577.1|ensembl:ENSG00000166508(gene)|ensembl:ENST00000303887(transcript)|go:"GO:0000727"(double-strand break repair via break-induced replication)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0000785"(chromatin)|go:"GO:0003678"(DNA helicase activity)|go:"GO:0003688"(DNA replication origin binding)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0016020"(membrane)|go:"GO:0042325"(regulation of phosphorylation)|go:"GO:0042493"|go:"GO:0042555"(MCM complex)|go:"GO:0071162"(CMG complex)|go:"GO:0071364"(cellular response to epidermal growth factor stimulus)|go:"GO:0071466"(cellular response to xenobiotic stimulus)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|interpro:IPR001208(MCM)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006260"(DNA replication)|go:"GO:0006267"(pre-replicative complex assembly involved in nuclear cell cycle DNA replication)|go:"GO:0006268"(DNA unwinding involved in DNA replication)|go:"GO:0006270"(DNA replication initiation)|go:"GO:0006271"(DNA strand elongation involved in DNA replication)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0008283"(cell population proliferation)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR008050(MCM protein 7)|interpro:IPR012340(Nucleic acid-binding, OB-fold)|interpro:IPR018525|interpro:IPR027417|interpro:IPR027925|interpro:IPR031327|interpro:IPR033762|interpro:IPR041562|mint:P33993|rcsb pdb:6XTX|rcsb pdb:6XTY|reactome:R-HSA-176187|reactome:R-HSA-176974|reactome:R-HSA-68867|reactome:R-HSA-68949|reactome:R-HSA-68962|reactome:R-HSA-69052|dip:DIP-27580N - - - figure legend:Fig. 5A, Supp. Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells) - 2020/05/21 2021/04/12 rogid:WEdwMYKpu1uQll5NXnMm4P51R4E9606 rogid:hrpCntkzdVgewNA+/iPS6b50dGY9606 rigid:1P63pNv1yn3F27gcT2OsGH/3EDQ false green fluorescent protein tag:n-n|mutation disrupting interaction strength:406-406,404-404 - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q8NHP6 uniprotkb:F8WAE5 intact:EBI-2812848|uniprotkb:Q8NA83|uniprotkb:Q8N3H2|ensembl:ENSP00000369860 intact:EBI-25617774|ensembl:ENSP00000273435 psi-mi:mspd2_human(display_long)|uniprotkb:MOSPD2(gene name)|psi-mi:MOSPD2(display_short) psi-mi:f8wae5_human(display_long)|uniprotkb:EIF2A(gene name)|psi-mi:EIF2A(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Di et al. (2018) pubmed:29858488|imex:IM-28178 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-25617558|imex:IM-28178-11 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001170946.1|refseq:NP_689794.1|go:"GO:0090023"(positive regulation of neutrophil chemotaxis)|go:"GO:0090026"(positive regulation of monocyte chemotaxis)|go:"GO:0140284"(endoplasmic reticulum-endosome membrane contact site)|interpro:IPR000535(Major sperm protein)|interpro:IPR001251(Cellular retinaldehyde-binding/triple function, C-terminal)|interpro:IPR008962(PapD-like)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR036273|interpro:IPR036865|mint:Q8NHP6|rcsb pdb:6TQS|rcsb pdb:6TQT|rcsb pdb:6TQU|reactome:R-HSA-6798695|reactome:R-HSA-9013405|ensembl:ENSG00000130150(gene)|ensembl:ENST00000380492(transcript)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006935"(chemotaxis)|go:"GO:0016020"(membrane)|go:"GO:0035579"(specific granule membrane)|go:"GO:0044232"(organelle membrane contact site) ensembl:ENSG00000144895(gene)|ensembl:ENST00000273435(transcript)|go:"GO:0003743"(translation initiation factor activity)|interpro:IPR011387(Translation initiation factor eIF-2A)|interpro:IPR013979(Eukaryotic translation initiation factor 2A, central region)|interpro:IPR015943(WD40/YVTN repeat-like)|refseq:NP_001305974.1 - - - figure legend:Fig. 5A, Supp. Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells) - 2020/05/21 2021/04/12 rogid:WEdwMYKpu1uQll5NXnMm4P51R4E9606 rogid:QJRX3HBsuM8Hy8StDV6HPZImx0M9606 rigid:1P63pNv1yn3F27gcT2OsGH/3EDQ false green fluorescent protein tag:n-n|mutation disrupting interaction strength:406-406,404-404 - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q8NHP6 uniprotkb:E7ETK0 intact:EBI-2812848|uniprotkb:Q8NA83|uniprotkb:Q8N3H2|ensembl:ENSP00000369860 intact:EBI-25617761|ensembl:ENSP00000415549 psi-mi:mspd2_human(display_long)|uniprotkb:MOSPD2(gene name)|psi-mi:MOSPD2(display_short) psi-mi:e7etk0_human(display_long)|uniprotkb:RPS24(gene name)|psi-mi:RPS24(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Di et al. (2018) pubmed:29858488|imex:IM-28178 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-25617558|imex:IM-28178-11 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001170946.1|refseq:NP_689794.1|go:"GO:0090023"(positive regulation of neutrophil chemotaxis)|go:"GO:0090026"(positive regulation of monocyte chemotaxis)|go:"GO:0140284"(endoplasmic reticulum-endosome membrane contact site)|interpro:IPR000535(Major sperm protein)|interpro:IPR001251(Cellular retinaldehyde-binding/triple function, C-terminal)|interpro:IPR008962(PapD-like)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR036273|interpro:IPR036865|mint:Q8NHP6|rcsb pdb:6TQS|rcsb pdb:6TQT|rcsb pdb:6TQU|reactome:R-HSA-6798695|reactome:R-HSA-9013405|ensembl:ENSG00000130150(gene)|ensembl:ENST00000380492(transcript)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006935"(chemotaxis)|go:"GO:0016020"(membrane)|go:"GO:0035579"(specific granule membrane)|go:"GO:0044232"(organelle membrane contact site) ensembl:ENSG00000138326(gene)|ensembl:ENST00000435275(transcript)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005829"(cytosol)|go:"GO:0005840"(ribosome)|go:"GO:0006412"(translation)|interpro:IPR001976(Ribosomal protein S24e)|interpro:IPR012678(Ribosomal protein L23/L15e, core)|interpro:IPR018098|rcsb pdb:6ZVJ|rcsb pdb:7A09 - - - figure legend:Fig. 5A, Supp. Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells) - 2020/05/21 2021/04/12 rogid:WEdwMYKpu1uQll5NXnMm4P51R4E9606 rogid:Pm8ixG9+zH0UJuOG2HDx6ALJtA09606 rigid:1P63pNv1yn3F27gcT2OsGH/3EDQ false green fluorescent protein tag:n-n|mutation disrupting interaction strength:406-406,404-404 - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q8NHP6 uniprotkb:P22695 intact:EBI-2812848|uniprotkb:Q8NA83|uniprotkb:Q8N3H2|ensembl:ENSP00000369860 intact:EBI-1051424|uniprotkb:Q9BQ05|uniprotkb:B3KSN4|ensembl:ENSP00000268379 psi-mi:mspd2_human(display_long)|uniprotkb:MOSPD2(gene name)|psi-mi:MOSPD2(display_short) psi-mi:qcr2_human(display_long)|uniprotkb:Ubiquinol-cytochrome-c reductase complex core protein 2(gene name synonym)|uniprotkb:Core protein II(gene name synonym)|uniprotkb:Complex III subunit 2(gene name synonym)|uniprotkb:UQCRC2(gene name)|psi-mi:UQCRC2(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Di et al. (2018) pubmed:29858488|imex:IM-28178 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-25617558|imex:IM-28178-11 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001170946.1|refseq:NP_689794.1|go:"GO:0090023"(positive regulation of neutrophil chemotaxis)|go:"GO:0090026"(positive regulation of monocyte chemotaxis)|go:"GO:0140284"(endoplasmic reticulum-endosome membrane contact site)|interpro:IPR000535(Major sperm protein)|interpro:IPR001251(Cellular retinaldehyde-binding/triple function, C-terminal)|interpro:IPR008962(PapD-like)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR036273|interpro:IPR036865|mint:Q8NHP6|rcsb pdb:6TQS|rcsb pdb:6TQT|rcsb pdb:6TQU|reactome:R-HSA-6798695|reactome:R-HSA-9013405|ensembl:ENSG00000130150(gene)|ensembl:ENST00000380492(transcript)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006935"(chemotaxis)|go:"GO:0016020"(membrane)|go:"GO:0035579"(specific granule membrane)|go:"GO:0044232"(organelle membrane contact site) refseq:NP_003357.2|ensembl:ENSG00000140740(gene)|ensembl:ENST00000268379(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005750"(mitochondrial respiratory chain complex III)|go:"GO:0005751"(mitochondrial respiratory chain complex IV)|go:"GO:0006119"(oxidative phosphorylation)|go:"GO:0006508"(proteolysis)|go:"GO:0009060"(aerobic respiration)|go:"GO:0042493"|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0046872"(metal ion binding)|interpro:IPR001431(Peptidase M16, zinc-binding site)|interpro:IPR007863(Peptidase M16, C-terminal)|interpro:IPR011249(Metalloenzyme, LuxS/M16 peptidase-like, metal-binding)|interpro:IPR011765(Peptidase M16, N-terminal)|mint:P22695|rcsb pdb:5XTE|rcsb pdb:5XTH|rcsb pdb:5XTI|reactome:R-HSA-611105 - - - figure legend:Fig. 5A, Supp. Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells) - 2020/05/21 2021/04/12 rogid:WEdwMYKpu1uQll5NXnMm4P51R4E9606 rogid:++DmwaVpqzRyxFl7mh62L4ku4P09606 rigid:1P63pNv1yn3F27gcT2OsGH/3EDQ false green fluorescent protein tag:n-n|mutation disrupting interaction strength:406-406,404-404 - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q8NHP6 uniprotkb:A0A0D9SF54 intact:EBI-2812848|uniprotkb:Q8NA83|uniprotkb:Q8N3H2|ensembl:ENSP00000369860 intact:EBI-25617739|ensembl:ENSP00000486308 psi-mi:mspd2_human(display_long)|uniprotkb:MOSPD2(gene name)|psi-mi:MOSPD2(display_short) psi-mi:a0a0d9sf54_human(display_long)|uniprotkb:SPTAN1(gene name)|psi-mi:SPTAN1(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Di et al. (2018) pubmed:29858488|imex:IM-28178 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-25617558|imex:IM-28178-11 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001170946.1|refseq:NP_689794.1|go:"GO:0090023"(positive regulation of neutrophil chemotaxis)|go:"GO:0090026"(positive regulation of monocyte chemotaxis)|go:"GO:0140284"(endoplasmic reticulum-endosome membrane contact site)|interpro:IPR000535(Major sperm protein)|interpro:IPR001251(Cellular retinaldehyde-binding/triple function, C-terminal)|interpro:IPR008962(PapD-like)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR036273|interpro:IPR036865|mint:Q8NHP6|rcsb pdb:6TQS|rcsb pdb:6TQT|rcsb pdb:6TQU|reactome:R-HSA-6798695|reactome:R-HSA-9013405|ensembl:ENSG00000130150(gene)|ensembl:ENST00000380492(transcript)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006935"(chemotaxis)|go:"GO:0016020"(membrane)|go:"GO:0035579"(specific granule membrane)|go:"GO:0044232"(organelle membrane contact site) ensembl:ENSG00000197694(gene)|ensembl:ENST00000630804(transcript)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005938"(cell cortex)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0051693"(actin filament capping)|interpro:IPR001452(Src homology-3)|interpro:IPR002017(Spectrin repeat)|interpro:IPR002048(Calcium-binding EF-hand)|interpro:IPR011992(EF-Hand type)|interpro:IPR014837(EF-hand, Ca insensitive)|interpro:IPR018159|interpro:IPR018247|interpro:IPR035825|interpro:IPR036028|go:"GO:0003779"(actin binding)|refseq:XP_016870550.1 - - - figure legend:Fig. 5A, Supp. Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells) - 2020/05/21 2021/04/12 rogid:WEdwMYKpu1uQll5NXnMm4P51R4E9606 rogid:11Hwn90M9Vrq9MgiwEbHOmzu9mE9606 rigid:1P63pNv1yn3F27gcT2OsGH/3EDQ false green fluorescent protein tag:n-n|mutation disrupting interaction strength:406-406,404-404 - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q8NHP6 uniprotkb:P09923 intact:EBI-2812848|uniprotkb:Q8NA83|uniprotkb:Q8N3H2|ensembl:ENSP00000369860 intact:EBI-1052631|uniprotkb:Q53S80|uniprotkb:Q9UBV5|uniprotkb:Q9UCL2|uniprotkb:B2R7Y4|ensembl:ENSP00000295463 psi-mi:mspd2_human(display_long)|uniprotkb:MOSPD2(gene name)|psi-mi:MOSPD2(display_short) psi-mi:ppbi_human(display_long)|uniprotkb:ALPI(gene name)|psi-mi:ALPI(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Di et al. (2018) pubmed:29858488|imex:IM-28178 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-25617558|imex:IM-28178-11 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001170946.1|refseq:NP_689794.1|go:"GO:0090023"(positive regulation of neutrophil chemotaxis)|go:"GO:0090026"(positive regulation of monocyte chemotaxis)|go:"GO:0140284"(endoplasmic reticulum-endosome membrane contact site)|interpro:IPR000535(Major sperm protein)|interpro:IPR001251(Cellular retinaldehyde-binding/triple function, C-terminal)|interpro:IPR008962(PapD-like)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR036273|interpro:IPR036865|mint:Q8NHP6|rcsb pdb:6TQS|rcsb pdb:6TQT|rcsb pdb:6TQU|reactome:R-HSA-6798695|reactome:R-HSA-9013405|ensembl:ENSG00000130150(gene)|ensembl:ENST00000380492(transcript)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006935"(chemotaxis)|go:"GO:0016020"(membrane)|go:"GO:0035579"(specific granule membrane)|go:"GO:0044232"(organelle membrane contact site) refseq:NP_001622.2|ensembl:ENSG00000163295(gene)|ensembl:ENST00000295463(transcript)|go:"GO:0000287"(magnesium ion binding)|go:"GO:0002020"(protease binding)|go:"GO:0004035"(alkaline phosphatase activity)|go:"GO:0005576"(extracellular region)|go:"GO:0005886"(plasma membrane)|go:"GO:0008270"(zinc ion binding)|go:"GO:0016311"(dephosphorylation)|go:"GO:0031225"(anchored component of membrane)|interpro:IPR001952(Alkaline phosphatase)|interpro:IPR017850(Alkaline-phosphatase-like, core domain)|interpro:IPR018299|reactome:R-HSA-1483166|reactome:R-HSA-163125|reactome:R-HSA-8935690 - - - figure legend:Fig. 5A, Supp. Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells) - 2020/05/21 2021/04/12 rogid:WEdwMYKpu1uQll5NXnMm4P51R4E9606 rogid:RVz6SrTgIp87b+FLyMYQuoQDsI49606 rigid:1P63pNv1yn3F27gcT2OsGH/3EDQ false green fluorescent protein tag:n-n|mutation disrupting interaction strength:406-406,404-404 - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q8NHP6 uniprotkb:Q8WXX5 intact:EBI-2812848|uniprotkb:Q8NA83|uniprotkb:Q8N3H2|ensembl:ENSP00000369860 intact:EBI-2349100|uniprotkb:B2RMW6|ensembl:ENSP00000362041 psi-mi:mspd2_human(display_long)|uniprotkb:MOSPD2(gene name)|psi-mi:MOSPD2(display_short) psi-mi:dnjc9_human(display_long)|uniprotkb:DNAJC9(gene name)|psi-mi:DNAJC9(display_short)|uniprotkb:DnaJ protein SB73(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Di et al. (2018) pubmed:29858488|imex:IM-28178 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-25617558|imex:IM-28178-11 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001170946.1|refseq:NP_689794.1|go:"GO:0090023"(positive regulation of neutrophil chemotaxis)|go:"GO:0090026"(positive regulation of monocyte chemotaxis)|go:"GO:0140284"(endoplasmic reticulum-endosome membrane contact site)|interpro:IPR000535(Major sperm protein)|interpro:IPR001251(Cellular retinaldehyde-binding/triple function, C-terminal)|interpro:IPR008962(PapD-like)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR036273|interpro:IPR036865|mint:Q8NHP6|rcsb pdb:6TQS|rcsb pdb:6TQT|rcsb pdb:6TQU|reactome:R-HSA-6798695|reactome:R-HSA-9013405|ensembl:ENSG00000130150(gene)|ensembl:ENST00000380492(transcript)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006935"(chemotaxis)|go:"GO:0016020"(membrane)|go:"GO:0035579"(specific granule membrane)|go:"GO:0044232"(organelle membrane contact site) refseq:NP_056005.1|ensembl:ENSG00000213551(gene)|ensembl:ENST00000372950(transcript)|go:"GO:0005615"(extracellular space)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0031072"(heat shock protein binding)|go:"GO:0032781"(positive regulation of ATP-dependent activity)|interpro:IPR001623(Heat shock protein DnaJ, N-terminal)|interpro:IPR018253|interpro:IPR036869|mint:Q8WXX5|rcsb pdb:7CIZ|rcsb pdb:7CJ0|go:"GO:0005829"(cytosol) - - - figure legend:Fig. 5A, Supp. Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells) - 2020/05/21 2021/04/12 rogid:WEdwMYKpu1uQll5NXnMm4P51R4E9606 rogid:K1fhi/D2XXu0PXipEvxGKWyDMMI9606 rigid:1P63pNv1yn3F27gcT2OsGH/3EDQ false green fluorescent protein tag:n-n|mutation disrupting interaction strength:406-406,404-404 - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q8NHP6 uniprotkb:P62424 intact:EBI-2812848|uniprotkb:Q8NA83|uniprotkb:Q8N3H2|ensembl:ENSP00000369860 intact:EBI-354172|uniprotkb:P11518|uniprotkb:Q5T8U4|ensembl:ENSP00000361076|ensembl:ENSP00000487443 psi-mi:mspd2_human(display_long)|uniprotkb:MOSPD2(gene name)|psi-mi:MOSPD2(display_short) psi-mi:rl7a_human(display_long)|uniprotkb:RPL7A(gene name)|psi-mi:RPL7A(display_short)|uniprotkb:SURF-3(gene name synonym)|uniprotkb:SURF3(gene name synonym)|uniprotkb:Surfeit locus protein 3(gene name synonym)|uniprotkb:PLA-X polypeptide(gene name synonym)|uniprotkb:Large ribosomal subunit protein eL8(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Di et al. (2018) pubmed:29858488|imex:IM-28178 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-25617558|imex:IM-28178-11 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001170946.1|refseq:NP_689794.1|go:"GO:0090023"(positive regulation of neutrophil chemotaxis)|go:"GO:0090026"(positive regulation of monocyte chemotaxis)|go:"GO:0140284"(endoplasmic reticulum-endosome membrane contact site)|interpro:IPR000535(Major sperm protein)|interpro:IPR001251(Cellular retinaldehyde-binding/triple function, C-terminal)|interpro:IPR008962(PapD-like)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR036273|interpro:IPR036865|mint:Q8NHP6|rcsb pdb:6TQS|rcsb pdb:6TQT|rcsb pdb:6TQU|reactome:R-HSA-6798695|reactome:R-HSA-9013405|ensembl:ENSG00000130150(gene)|ensembl:ENST00000380492(transcript)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006935"(chemotaxis)|go:"GO:0016020"(membrane)|go:"GO:0035579"(specific granule membrane)|go:"GO:0044232"(organelle membrane contact site) refseq:NP_000963.1|dip:DIP-31502N|ensembl:ENSG00000148303(gene)|ensembl:ENSG00000280858(gene)|ensembl:ENST00000323345(transcript)|ensembl:ENST00000630979(transcript)|go:"GO:0000470"(maturation of LSU-rRNA)|go:"GO:0002181"(cytoplasmic translation)|go:"GO:0003723"(RNA binding)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005925"(focal adhesion)|go:"GO:0006412"(translation)|go:"GO:0016020"(membrane)|go:"GO:0022625"(cytosolic large ribosomal subunit)|go:"GO:0022626"(cytosolic ribosome)|go:"GO:0042788"(polysomal ribosome)|go:"GO:0045296"(cadherin binding)|interpro:IPR001921(Ribosomal protein L7A)|interpro:IPR004037(Ribosomal protein L7Ae)|interpro:IPR004038(Ribosomal protein L7Ae/L30e/S12e/Gadd45)|interpro:IPR018492|interpro:IPR029064|mint:P62424|rcsb pdb:4UG0|rcsb pdb:4V6X|rcsb pdb:5AJ0|rcsb pdb:5LKS|rcsb pdb:5T2C|go:"GO:0005634"(nucleus)|rcsb pdb:6EK0|rcsb pdb:6IP5|rcsb pdb:6IP6|rcsb pdb:6IP8|rcsb pdb:6LQM|rcsb pdb:6LSR|rcsb pdb:6LSS|rcsb pdb:6LU8|rcsb pdb:6OLE|rcsb pdb:6OLF|rcsb pdb:6OLG|rcsb pdb:6OLI|rcsb pdb:6OLZ|rcsb pdb:6OM0|rcsb pdb:6OM7|rcsb pdb:6QZP|rcsb pdb:6W6L|rcsb pdb:6XA1|rcsb pdb:6Y0G|rcsb pdb:6Y2L|rcsb pdb:6Y57|rcsb pdb:6Y6X|rcsb pdb:6Z6L|rcsb pdb:6Z6M|rcsb pdb:6Z6N|rcsb pdb:6ZM7|rcsb pdb:6ZME|rcsb pdb:6ZMI|rcsb pdb:6ZMO|rcsb pdb:7BHP|reactome:R-HSA-156827|reactome:R-HSA-156902|reactome:R-HSA-1799339|reactome:R-HSA-192823|reactome:R-HSA-2408557|reactome:R-HSA-6791226|reactome:R-HSA-72689|reactome:R-HSA-72706|reactome:R-HSA-72764|reactome:R-HSA-9010553|reactome:R-HSA-9633012|reactome:R-HSA-975956|reactome:R-HSA-975957 - - - figure legend:Fig. 5A, Supp. Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells) - 2020/05/21 2021/04/12 rogid:WEdwMYKpu1uQll5NXnMm4P51R4E9606 rogid:shPtLmc+oabT/rSwho+tP1iJy4k9606 rigid:1P63pNv1yn3F27gcT2OsGH/3EDQ false green fluorescent protein tag:n-n|mutation disrupting interaction strength:406-406,404-404 - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q8NHP6 uniprotkb:P62750 intact:EBI-2812848|uniprotkb:Q8NA83|uniprotkb:Q8N3H2|ensembl:ENSP00000369860 intact:EBI-353254|uniprotkb:P29316|uniprotkb:Q92774|uniprotkb:P39024|uniprotkb:B2R5B2|ensembl:ENSP00000389103 psi-mi:mspd2_human(display_long)|uniprotkb:MOSPD2(gene name)|psi-mi:MOSPD2(display_short) psi-mi:rl23a_human(display_long)|uniprotkb:RPL23A(gene name)|psi-mi:RPL23A(display_short)|uniprotkb:Large ribosomal subunit protein uL23(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Di et al. (2018) pubmed:29858488|imex:IM-28178 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-25617558|imex:IM-28178-11 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001170946.1|refseq:NP_689794.1|go:"GO:0090023"(positive regulation of neutrophil chemotaxis)|go:"GO:0090026"(positive regulation of monocyte chemotaxis)|go:"GO:0140284"(endoplasmic reticulum-endosome membrane contact site)|interpro:IPR000535(Major sperm protein)|interpro:IPR001251(Cellular retinaldehyde-binding/triple function, C-terminal)|interpro:IPR008962(PapD-like)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR036273|interpro:IPR036865|mint:Q8NHP6|rcsb pdb:6TQS|rcsb pdb:6TQT|rcsb pdb:6TQU|reactome:R-HSA-6798695|reactome:R-HSA-9013405|ensembl:ENSG00000130150(gene)|ensembl:ENST00000380492(transcript)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006935"(chemotaxis)|go:"GO:0016020"(membrane)|go:"GO:0035579"(specific granule membrane)|go:"GO:0044232"(organelle membrane contact site) reactome:R-HSA-72706|reactome:R-HSA-72764|reactome:R-HSA-9010553|reactome:R-HSA-9633012|reactome:R-HSA-975956|reactome:R-HSA-975957|rcsb pdb:6Y57|rcsb pdb:6Y6X|rcsb pdb:6Z6L|rcsb pdb:6Z6M|rcsb pdb:6Z6N|rcsb pdb:6ZM7|rcsb pdb:6ZME|rcsb pdb:6ZMI|rcsb pdb:6ZMO|rcsb pdb:7BHP|reactome:R-HSA-156827|reactome:R-HSA-156902|reactome:R-HSA-1799339|reactome:R-HSA-192823|reactome:R-HSA-2408557|reactome:R-HSA-6791226|reactome:R-HSA-72689|rcsb pdb:5T2C|rcsb pdb:6EK0|rcsb pdb:6IP5|rcsb pdb:6IP6|rcsb pdb:6IP8|rcsb pdb:6LQM|rcsb pdb:6LSR|rcsb pdb:6LSS|rcsb pdb:6LU8|rcsb pdb:6OLE|rcsb pdb:6OLF|rcsb pdb:6OLG|rcsb pdb:6OLI|rcsb pdb:6OLZ|rcsb pdb:6OM0|rcsb pdb:6OM7|rcsb pdb:6QZP|rcsb pdb:6SXO|rcsb pdb:6W6L|rcsb pdb:6XA1|rcsb pdb:6Y0G|rcsb pdb:6Y2L|refseq:NP_000975.2|ensembl:ENSG00000198242(gene)|ensembl:ENST00000422514(transcript)|go:"GO:0000027"(ribosomal large subunit assembly)|go:"GO:0002181"(cytoplasmic translation)|go:"GO:0003723"(RNA binding)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005634"(nucleus)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006412"(translation)|go:"GO:0019843"(rRNA binding)|go:"GO:0022625"(cytosolic large ribosomal subunit)|go:"GO:0022626"(cytosolic ribosome)|go:"GO:0045296"(cadherin binding)|go:"GO:0070062"(extracellular exosome)|go:"GO:1904841"(TORC2 complex binding)|interpro:IPR001014(Ribosomal protein L23, conserved site)|interpro:IPR005633(Ribosomal protein L23/L25, N-terminal)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR012678(Ribosomal protein L23/L15e, core)|interpro:IPR013025(Ribosomal protein L25/L23)|interpro:IPR019985|mint:P62750|rcsb pdb:4UG0|rcsb pdb:4V6X|rcsb pdb:5AJ0|rcsb pdb:5LKS - - - figure legend:Fig. 5A, Supp. Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells) - 2020/05/21 2021/04/12 rogid:WEdwMYKpu1uQll5NXnMm4P51R4E9606 rogid:lA1ubRFO9/Tl54Z1dKUzoCKvpAo9606 rigid:1P63pNv1yn3F27gcT2OsGH/3EDQ false green fluorescent protein tag:n-n|mutation disrupting interaction strength:406-406,404-404 - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q8NHP6 uniprotkb:A0A0J9YYL3 intact:EBI-2812848|uniprotkb:Q8NA83|uniprotkb:Q8N3H2|ensembl:ENSP00000369860 intact:EBI-25617723|ensembl:ENSP00000488903 psi-mi:mspd2_human(display_long)|uniprotkb:MOSPD2(gene name)|psi-mi:MOSPD2(display_short) psi-mi:a0a0j9yyl3_human(display_long)|uniprotkb:PUF60(gene name)|psi-mi:PUF60(display_short)|uniprotkb:"Poly(U)-binding-splicing factor PUF60"(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Di et al. (2018) pubmed:29858488|imex:IM-28178 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-25617558|imex:IM-28178-11 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001170946.1|refseq:NP_689794.1|go:"GO:0090023"(positive regulation of neutrophil chemotaxis)|go:"GO:0090026"(positive regulation of monocyte chemotaxis)|go:"GO:0140284"(endoplasmic reticulum-endosome membrane contact site)|interpro:IPR000535(Major sperm protein)|interpro:IPR001251(Cellular retinaldehyde-binding/triple function, C-terminal)|interpro:IPR008962(PapD-like)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR036273|interpro:IPR036865|mint:Q8NHP6|rcsb pdb:6TQS|rcsb pdb:6TQT|rcsb pdb:6TQU|reactome:R-HSA-6798695|reactome:R-HSA-9013405|ensembl:ENSG00000130150(gene)|ensembl:ENST00000380492(transcript)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006935"(chemotaxis)|go:"GO:0016020"(membrane)|go:"GO:0035579"(specific granule membrane)|go:"GO:0044232"(organelle membrane contact site) ensembl:ENSG00000274081(gene)|ensembl:ENST00000634206(transcript)|go:"GO:0000381"(regulation of alternative mRNA splicing, via spliceosome)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0006397"(mRNA processing)|go:"GO:0008380"(RNA splicing)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR003954(RNA recognition, region 1)|interpro:IPR006532(Poly-U binding splicing factor, half-pint)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR034209|interpro:IPR034211|interpro:IPR034212|interpro:IPR035979 - - - figure legend:Fig. 5A, Supp. Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells) - 2020/05/21 2021/04/12 rogid:WEdwMYKpu1uQll5NXnMm4P51R4E9606 rogid:chT/GKidqGuj7fkEHL6/yJm4bfM9606 rigid:1P63pNv1yn3F27gcT2OsGH/3EDQ false green fluorescent protein tag:n-n|mutation disrupting interaction strength:406-406,404-404 - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q8NHP6 uniprotkb:A0A087X0U3 intact:EBI-2812848|uniprotkb:Q8NA83|uniprotkb:Q8N3H2|ensembl:ENSP00000369860 intact:EBI-25617710|ensembl:ENSP00000483657 psi-mi:mspd2_human(display_long)|uniprotkb:MOSPD2(gene name)|psi-mi:MOSPD2(display_short) psi-mi:a0a087x0u3_human(display_long)|uniprotkb:SLC1A3(gene name)|psi-mi:SLC1A3(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Di et al. (2018) pubmed:29858488|imex:IM-28178 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-25617558|imex:IM-28178-11 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001170946.1|refseq:NP_689794.1|go:"GO:0090023"(positive regulation of neutrophil chemotaxis)|go:"GO:0090026"(positive regulation of monocyte chemotaxis)|go:"GO:0140284"(endoplasmic reticulum-endosome membrane contact site)|interpro:IPR000535(Major sperm protein)|interpro:IPR001251(Cellular retinaldehyde-binding/triple function, C-terminal)|interpro:IPR008962(PapD-like)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR036273|interpro:IPR036865|mint:Q8NHP6|rcsb pdb:6TQS|rcsb pdb:6TQT|rcsb pdb:6TQU|reactome:R-HSA-6798695|reactome:R-HSA-9013405|ensembl:ENSG00000130150(gene)|ensembl:ENST00000380492(transcript)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006935"(chemotaxis)|go:"GO:0016020"(membrane)|go:"GO:0035579"(specific granule membrane)|go:"GO:0044232"(organelle membrane contact site) ensembl:ENSG00000079215(gene)|ensembl:ENST00000612708(transcript)|go:"GO:0015293"(symporter activity)|go:"GO:0016021"(integral component of membrane)|interpro:IPR001991("Sodium:dicarboxylate symporter")|interpro:IPR018107|interpro:IPR036458|refseq:NP_001276869.1 - - - figure legend:Fig. 5A, Supp. Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells) - 2020/05/21 2021/04/12 rogid:WEdwMYKpu1uQll5NXnMm4P51R4E9606 rogid:F2OKSMYs/i9d4CPyojJbwnnEBxU9606 rigid:1P63pNv1yn3F27gcT2OsGH/3EDQ false green fluorescent protein tag:n-n|mutation disrupting interaction strength:406-406,404-404 - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q8NHP6 uniprotkb:J3QQQ9 intact:EBI-2812848|uniprotkb:Q8NA83|uniprotkb:Q8N3H2|ensembl:ENSP00000369860 intact:EBI-25617693|ensembl:ENSP00000463847 psi-mi:mspd2_human(display_long)|uniprotkb:MOSPD2(gene name)|psi-mi:MOSPD2(display_short) psi-mi:j3qqq9_human(display_long) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Di et al. (2018) pubmed:29858488|imex:IM-28178 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-25617558|imex:IM-28178-11 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001170946.1|refseq:NP_689794.1|go:"GO:0090023"(positive regulation of neutrophil chemotaxis)|go:"GO:0090026"(positive regulation of monocyte chemotaxis)|go:"GO:0140284"(endoplasmic reticulum-endosome membrane contact site)|interpro:IPR000535(Major sperm protein)|interpro:IPR001251(Cellular retinaldehyde-binding/triple function, C-terminal)|interpro:IPR008962(PapD-like)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR036273|interpro:IPR036865|mint:Q8NHP6|rcsb pdb:6TQS|rcsb pdb:6TQT|rcsb pdb:6TQU|reactome:R-HSA-6798695|reactome:R-HSA-9013405|ensembl:ENSG00000130150(gene)|ensembl:ENST00000380492(transcript)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006935"(chemotaxis)|go:"GO:0016020"(membrane)|go:"GO:0035579"(specific granule membrane)|go:"GO:0044232"(organelle membrane contact site) interpro:IPR005756(Ribosomal protein L26, eukaryotic/archaeal)|interpro:IPR005824(KOW)|interpro:IPR005825(Ribosomal protein L24/L26, conserved site)|interpro:IPR008991(Translation protein SH3-like)|interpro:IPR014722(Translation protein SH3-like, subgroup)|interpro:IPR041988|go:"GO:0015934"(large ribosomal subunit)|ensembl:ENSG00000263809(gene)|ensembl:ENST00000582471(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0006412"(translation) - - - figure legend:Fig. 5A, Supp. Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells) - 2020/05/21 2021/04/12 rogid:WEdwMYKpu1uQll5NXnMm4P51R4E9606 rogid:PnfHOtkFzqEI50G3uwWmNUnYkzo9606 rigid:1P63pNv1yn3F27gcT2OsGH/3EDQ false green fluorescent protein tag:n-n|mutation disrupting interaction strength:406-406,404-404 - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q8NHP6 uniprotkb:Q96AG4 intact:EBI-2812848|uniprotkb:Q8NA83|uniprotkb:Q8N3H2|ensembl:ENSP00000369860 intact:EBI-358888|uniprotkb:Q9P189|uniprotkb:D3DTX8|ensembl:ENSP00000225972|uniprotkb:B2RE83 psi-mi:mspd2_human(display_long)|uniprotkb:MOSPD2(gene name)|psi-mi:MOSPD2(display_short) psi-mi:lrc59_human(display_long)|uniprotkb:LRRC59(gene name)|psi-mi:LRRC59(display_short)|uniprotkb:Ribosome-binding protein p34(gene name synonym)|uniprotkb:PRO1855(orf name) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Di et al. (2018) pubmed:29858488|imex:IM-28178 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-25617558|imex:IM-28178-11 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001170946.1|refseq:NP_689794.1|go:"GO:0090023"(positive regulation of neutrophil chemotaxis)|go:"GO:0090026"(positive regulation of monocyte chemotaxis)|go:"GO:0140284"(endoplasmic reticulum-endosome membrane contact site)|interpro:IPR000535(Major sperm protein)|interpro:IPR001251(Cellular retinaldehyde-binding/triple function, C-terminal)|interpro:IPR008962(PapD-like)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR036273|interpro:IPR036865|mint:Q8NHP6|rcsb pdb:6TQS|rcsb pdb:6TQT|rcsb pdb:6TQU|reactome:R-HSA-6798695|reactome:R-HSA-9013405|ensembl:ENSG00000130150(gene)|ensembl:ENST00000380492(transcript)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006935"(chemotaxis)|go:"GO:0016020"(membrane)|go:"GO:0035579"(specific granule membrane)|go:"GO:0044232"(organelle membrane contact site) refseq:NP_060979.2|ensembl:ENSG00000108829(gene)|ensembl:ENST00000225972(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0007165"(signal transduction)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0042645"(mitochondrial nucleoid)|go:"GO:0045296"(cadherin binding)|go:"GO:0046579"(positive regulation of Ras protein signal transduction)|interpro:IPR001611(Leucine-rich repeat)|interpro:IPR003591(Leucine-rich repeat, typical subtype)|interpro:IPR032675|mint:Q96AG4 - - - figure legend:Fig. 5A, Supp. Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells) - 2020/05/21 2021/04/12 rogid:WEdwMYKpu1uQll5NXnMm4P51R4E9606 rogid:gAtWed9Jv69oHdkEFgpWGFnvcWE9606 rigid:1P63pNv1yn3F27gcT2OsGH/3EDQ false green fluorescent protein tag:n-n|mutation disrupting interaction strength:406-406,404-404 - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q8NHP6 uniprotkb:M0R0F0 intact:EBI-2812848|uniprotkb:Q8NA83|uniprotkb:Q8N3H2|ensembl:ENSP00000369860 intact:EBI-25617677|ensembl:ENSP00000471185 psi-mi:mspd2_human(display_long)|uniprotkb:MOSPD2(gene name)|psi-mi:MOSPD2(display_short) psi-mi:m0r0f0_human(display_long)|uniprotkb:RPS5(gene name)|psi-mi:RPS5(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Di et al. (2018) pubmed:29858488|imex:IM-28178 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-25617558|imex:IM-28178-11 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001170946.1|refseq:NP_689794.1|go:"GO:0090023"(positive regulation of neutrophil chemotaxis)|go:"GO:0090026"(positive regulation of monocyte chemotaxis)|go:"GO:0140284"(endoplasmic reticulum-endosome membrane contact site)|interpro:IPR000535(Major sperm protein)|interpro:IPR001251(Cellular retinaldehyde-binding/triple function, C-terminal)|interpro:IPR008962(PapD-like)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR036273|interpro:IPR036865|mint:Q8NHP6|rcsb pdb:6TQS|rcsb pdb:6TQT|rcsb pdb:6TQU|reactome:R-HSA-6798695|reactome:R-HSA-9013405|ensembl:ENSG00000130150(gene)|ensembl:ENST00000380492(transcript)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006935"(chemotaxis)|go:"GO:0016020"(membrane)|go:"GO:0035579"(specific granule membrane)|go:"GO:0044232"(organelle membrane contact site) ensembl:ENSG00000083845(gene)|ensembl:ENST00000596314(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0006412"(translation)|go:"GO:0015935"(small ribosomal subunit)|interpro:IPR000235(Ribosomal protein S7)|interpro:IPR005716(Ribosomal protein S7, eukaryotic/archaeal)|interpro:IPR020606|interpro:IPR023798|interpro:IPR036823 - - - figure legend:Fig. 5A, Supp. Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells) - 2020/05/21 2021/04/12 rogid:WEdwMYKpu1uQll5NXnMm4P51R4E9606 rogid:3ceaJ1M9KY7/jKixP6YofUX1ivc9606 rigid:1P63pNv1yn3F27gcT2OsGH/3EDQ false green fluorescent protein tag:n-n|mutation disrupting interaction strength:406-406,404-404 - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q8NHP6 uniprotkb:P54136 intact:EBI-2812848|uniprotkb:Q8NA83|uniprotkb:Q8N3H2|ensembl:ENSP00000369860 intact:EBI-355482|uniprotkb:Q9BWA1|uniprotkb:B2RBS9|uniprotkb:Q53GY4|intact:EBI-28985219|ensembl:ENSP00000231572 psi-mi:mspd2_human(display_long)|uniprotkb:MOSPD2(gene name)|psi-mi:MOSPD2(display_short) psi-mi:syrc_human(display_long)|uniprotkb:RARS1(gene name)|psi-mi:RARS1(display_short)|uniprotkb:Arginyl-tRNA synthetase(gene name synonym)|uniprotkb:RARS(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Di et al. (2018) pubmed:29858488|imex:IM-28178 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-25617558|imex:IM-28178-11 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001170946.1|refseq:NP_689794.1|go:"GO:0090023"(positive regulation of neutrophil chemotaxis)|go:"GO:0090026"(positive regulation of monocyte chemotaxis)|go:"GO:0140284"(endoplasmic reticulum-endosome membrane contact site)|interpro:IPR000535(Major sperm protein)|interpro:IPR001251(Cellular retinaldehyde-binding/triple function, C-terminal)|interpro:IPR008962(PapD-like)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR036273|interpro:IPR036865|mint:Q8NHP6|rcsb pdb:6TQS|rcsb pdb:6TQT|rcsb pdb:6TQU|reactome:R-HSA-6798695|reactome:R-HSA-9013405|ensembl:ENSG00000130150(gene)|ensembl:ENST00000380492(transcript)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006935"(chemotaxis)|go:"GO:0016020"(membrane)|go:"GO:0035579"(specific granule membrane)|go:"GO:0044232"(organelle membrane contact site) refseq:NP_002878.2|ensembl:ENSG00000113643(gene)|ensembl:ENST00000231572(transcript)|go:"GO:0000049"(tRNA binding)|go:"GO:0004814"(arginine-tRNA ligase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006418"(tRNA aminoacylation for protein translation)|go:"GO:0006420"(arginyl-tRNA aminoacylation)|go:"GO:0016020"(membrane)|go:"GO:0017101"(aminoacyl-tRNA synthetase multienzyme complex)|go:"GO:0034618"(arginine binding)|go:"GO:0045296"(cadherin binding)|go:"GO:0070062"(extracellular exosome)|interpro:IPR001278(Arginyl-tRNA synthetase, class Ic)|interpro:IPR001412(Aminoacyl-tRNA synthetase, class I, conserved site)|interpro:IPR005148(Arginyl tRNA synthetase, class Ic, N-terminal)|interpro:IPR008909(DALR anticodon binding)|interpro:IPR009080(Aminoacyl-tRNA synthetase, class 1a, anticodon-binding)|interpro:IPR014729(Rossmann-like alpha/beta/alpha sandwich fold)|interpro:IPR035684|interpro:IPR036695|mint:P54136|rcsb pdb:4Q2T|rcsb pdb:4Q2X|rcsb pdb:4Q2Y|rcsb pdb:4R3Z|rcsb pdb:4ZAJ|reactome:R-HSA-2408522|reactome:R-HSA-379716|ensembl:ENSP00000231572 - - - figure legend:Fig. 5A, Supp. Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells) - 2020/05/21 2021/04/12 rogid:WEdwMYKpu1uQll5NXnMm4P51R4E9606 rogid:oM9gWF1NucjgVjBFm4DcjmnQNCE9606 rigid:1P63pNv1yn3F27gcT2OsGH/3EDQ false green fluorescent protein tag:n-n|mutation disrupting interaction strength:406-406,404-404 - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q8NHP6 uniprotkb:J3QR09 intact:EBI-2812848|uniprotkb:Q8NA83|uniprotkb:Q8N3H2|ensembl:ENSP00000369860 intact:EBI-10970151|ensembl:ENSP00000463985 psi-mi:mspd2_human(display_long)|uniprotkb:MOSPD2(gene name)|psi-mi:MOSPD2(display_short) psi-mi:j3qr09_human(display_long)|uniprotkb:RPL19(gene name)|psi-mi:RPL19(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Di et al. (2018) pubmed:29858488|imex:IM-28178 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-25617558|imex:IM-28178-11 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001170946.1|refseq:NP_689794.1|go:"GO:0090023"(positive regulation of neutrophil chemotaxis)|go:"GO:0090026"(positive regulation of monocyte chemotaxis)|go:"GO:0140284"(endoplasmic reticulum-endosome membrane contact site)|interpro:IPR000535(Major sperm protein)|interpro:IPR001251(Cellular retinaldehyde-binding/triple function, C-terminal)|interpro:IPR008962(PapD-like)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR036273|interpro:IPR036865|mint:Q8NHP6|rcsb pdb:6TQS|rcsb pdb:6TQT|rcsb pdb:6TQU|reactome:R-HSA-6798695|reactome:R-HSA-9013405|ensembl:ENSG00000130150(gene)|ensembl:ENST00000380492(transcript)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006935"(chemotaxis)|go:"GO:0016020"(membrane)|go:"GO:0035579"(specific granule membrane)|go:"GO:0044232"(organelle membrane contact site) ensembl:ENSG00000108298(gene)|ensembl:ENST00000579374(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0006412"(translation)|go:"GO:0022625"(cytosolic large ribosomal subunit)|interpro:IPR000196(Ribosomal protein L19/L19e)|interpro:IPR015972(Ribosomal protein L19/L19e, domain 1)|interpro:IPR039547|interpro:IPR023638|interpro:IPR033935|interpro:IPR035970 - - - figure legend:Fig. 5A, Supp. Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells) - 2020/05/21 2021/04/12 rogid:WEdwMYKpu1uQll5NXnMm4P51R4E9606 rogid:/VYEYZh8BAHyA6ACsflxCkty4S89606 rigid:1P63pNv1yn3F27gcT2OsGH/3EDQ false green fluorescent protein tag:n-n|mutation disrupting interaction strength:406-406,404-404 - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q8NHP6 uniprotkb:Q8NC51 intact:EBI-2812848|uniprotkb:Q8NA83|uniprotkb:Q8N3H2|ensembl:ENSP00000369860 intact:EBI-523558|uniprotkb:Q8WUH0|uniprotkb:Q96SE2|uniprotkb:Q9BTY3|uniprotkb:Q9BUM4|uniprotkb:Q9Y367|uniprotkb:Q9Y4S3|uniprotkb:Q5VU19|intact:EBI-1058614|ensembl:ENSP00000360034|uniprotkb:Q5VU20|uniprotkb:Q5VU22 psi-mi:mspd2_human(display_long)|uniprotkb:MOSPD2(gene name)|psi-mi:MOSPD2(display_short) psi-mi:pairb_human(display_long)|uniprotkb:PAI1 RNA-binding protein 1(gene name synonym)|uniprotkb:SERPINE1 mRNA-binding protein 1(gene name synonym)|uniprotkb:CGI-55(orf name)|uniprotkb:SERBP1(gene name)|psi-mi:SERBP1(display_short)|uniprotkb:PAIRBP1(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Di et al. (2018) pubmed:29858488|imex:IM-28178 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-25617558|imex:IM-28178-11 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001170946.1|refseq:NP_689794.1|go:"GO:0090023"(positive regulation of neutrophil chemotaxis)|go:"GO:0090026"(positive regulation of monocyte chemotaxis)|go:"GO:0140284"(endoplasmic reticulum-endosome membrane contact site)|interpro:IPR000535(Major sperm protein)|interpro:IPR001251(Cellular retinaldehyde-binding/triple function, C-terminal)|interpro:IPR008962(PapD-like)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR036273|interpro:IPR036865|mint:Q8NHP6|rcsb pdb:6TQS|rcsb pdb:6TQT|rcsb pdb:6TQU|reactome:R-HSA-6798695|reactome:R-HSA-9013405|ensembl:ENSG00000130150(gene)|ensembl:ENST00000380492(transcript)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006935"(chemotaxis)|go:"GO:0016020"(membrane)|go:"GO:0035579"(specific granule membrane)|go:"GO:0044232"(organelle membrane contact site) ensembl:ENSG00000142864(gene)|ensembl:ENST00000370995(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0003730"(mRNA 3'-UTR binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0016020"(membrane)|go:"GO:0030578"(PML body organization)|go:"GO:0032183"(SUMO binding)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0043022"(ribosome binding)|go:"GO:0043488"(regulation of mRNA stability)|go:"GO:0045296"(cadherin binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0070062"(extracellular exosome)|interpro:IPR006861(Hyaluronan/mRNA binding protein)|interpro:IPR027205|interpro:IPR032381|interpro:IPR039764|mint:Q8NC51|rcsb pdb:4V6X|rcsb pdb:6Z6M|rcsb pdb:6Z6N|refseq:NP_001018077.1|refseq:NP_001018078.1|refseq:NP_001018079.1|refseq:NP_056455.3|dip:DIP-33819N - - - figure legend:Fig. 5A, Supp. Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells) - 2020/05/21 2021/04/12 rogid:WEdwMYKpu1uQll5NXnMm4P51R4E9606 rogid:lVkIPRkoXs3B4Qop1pA2zG/RKlo9606 rigid:1P63pNv1yn3F27gcT2OsGH/3EDQ false green fluorescent protein tag:n-n|mutation disrupting interaction strength:406-406,404-404 - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q8NHP6 uniprotkb:Q13835 intact:EBI-2812848|uniprotkb:Q8NA83|uniprotkb:Q8N3H2|ensembl:ENSP00000369860 intact:EBI-2513407|ensembl:ENSP00000263946|ensembl:ENSP00000295597|uniprotkb:O00645|uniprotkb:Q14CA0|uniprotkb:Q15152 psi-mi:mspd2_human(display_long)|uniprotkb:MOSPD2(gene name)|psi-mi:MOSPD2(display_short) psi-mi:pkp1_human(display_long)|uniprotkb:PKP1(gene name)|psi-mi:PKP1(display_short)|uniprotkb:Band 6 protein(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Di et al. (2018) pubmed:29858488|imex:IM-28178 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-25617558|imex:IM-28178-11 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001170946.1|refseq:NP_689794.1|go:"GO:0090023"(positive regulation of neutrophil chemotaxis)|go:"GO:0090026"(positive regulation of monocyte chemotaxis)|go:"GO:0140284"(endoplasmic reticulum-endosome membrane contact site)|interpro:IPR000535(Major sperm protein)|interpro:IPR001251(Cellular retinaldehyde-binding/triple function, C-terminal)|interpro:IPR008962(PapD-like)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR036273|interpro:IPR036865|mint:Q8NHP6|rcsb pdb:6TQS|rcsb pdb:6TQT|rcsb pdb:6TQU|reactome:R-HSA-6798695|reactome:R-HSA-9013405|ensembl:ENSG00000130150(gene)|ensembl:ENST00000380492(transcript)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006935"(chemotaxis)|go:"GO:0016020"(membrane)|go:"GO:0035579"(specific granule membrane)|go:"GO:0044232"(organelle membrane contact site) go:"GO:0007043"(cell-cell junction assembly)|go:"GO:0007155"(cell adhesion)|go:"GO:0007165"(signal transduction)|go:"GO:0005912"(adherens junction)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0019215"(intermediate filament binding)|go:"GO:0030057"(desmosome)|go:"GO:0030280"(structural constituent of skin epidermis)|go:"GO:0045110"(intermediate filament bundle assembly)|go:"GO:0045296"(cadherin binding)|go:"GO:0098609"(cell-cell adhesion)|go:"GO:0101003"(ficolin-1-rich granule membrane)|go:"GO:1902373"(negative regulation of mRNA catabolic process)|go:"GO:1990124"(messenger ribonucleoprotein complex)|interpro:IPR000225(Armadillo)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR028432|interpro:IPR028435|mint:Q13835|reactome:R-HSA-351906|reactome:R-HSA-6798695|reactome:R-HSA-6805567|reactome:R-HSA-6809371|rcsb pdb:1XM9|ensembl:ENSG00000081277(gene)|ensembl:ENST00000263946(transcript)|ensembl:ENST00000352845(transcript)|go:"GO:0001533"(cornified envelope)|go:"GO:0005521"(lamin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005882"(intermediate filament)|go:"GO:0005886"(plasma membrane)|refseq:NP_000290.2|refseq:NP_001005337.1 - - - figure legend:Fig. 5A, Supp. Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells) - 2020/05/21 2021/04/12 rogid:WEdwMYKpu1uQll5NXnMm4P51R4E9606 rogid:j2bzqEmWBUDLVnjl2JX/i4nI8P49606 rigid:1P63pNv1yn3F27gcT2OsGH/3EDQ false green fluorescent protein tag:n-n|mutation disrupting interaction strength:406-406,404-404 - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q8NHP6 uniprotkb:C9JPX5 intact:EBI-2812848|uniprotkb:Q8NA83|uniprotkb:Q8N3H2|ensembl:ENSP00000369860 intact:EBI-25617667|ensembl:ENSP00000402028 psi-mi:mspd2_human(display_long)|uniprotkb:MOSPD2(gene name)|psi-mi:MOSPD2(display_short) psi-mi:c9jpx5_human(display_long)|uniprotkb:STARD3NL(gene name)|psi-mi:STARD3NL(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Di et al. (2018) pubmed:29858488|imex:IM-28178 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-25617558|imex:IM-28178-11 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001170946.1|refseq:NP_689794.1|go:"GO:0090023"(positive regulation of neutrophil chemotaxis)|go:"GO:0090026"(positive regulation of monocyte chemotaxis)|go:"GO:0140284"(endoplasmic reticulum-endosome membrane contact site)|interpro:IPR000535(Major sperm protein)|interpro:IPR001251(Cellular retinaldehyde-binding/triple function, C-terminal)|interpro:IPR008962(PapD-like)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR036273|interpro:IPR036865|mint:Q8NHP6|rcsb pdb:6TQS|rcsb pdb:6TQT|rcsb pdb:6TQU|reactome:R-HSA-6798695|reactome:R-HSA-9013405|ensembl:ENSG00000130150(gene)|ensembl:ENST00000380492(transcript)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006935"(chemotaxis)|go:"GO:0016020"(membrane)|go:"GO:0035579"(specific granule membrane)|go:"GO:0044232"(organelle membrane contact site) ensembl:ENSG00000010270(gene)|ensembl:ENST00000429075(transcript)|go:"GO:0016021"(integral component of membrane)|go:"GO:0031902"(late endosome membrane)|go:"GO:0043231"(intracellular membrane-bounded organelle)|interpro:IPR019498 - - - figure legend:Fig. 5A, Supp. Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells) - 2020/05/21 2021/04/12 rogid:WEdwMYKpu1uQll5NXnMm4P51R4E9606 rogid:tBGvAcZIHRhe8zDcNYfwJBu6T6A9606 rigid:1P63pNv1yn3F27gcT2OsGH/3EDQ false green fluorescent protein tag:n-n|mutation disrupting interaction strength:406-406,404-404 - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q8NHP6 uniprotkb:Q15545 intact:EBI-2812848|uniprotkb:Q8NA83|uniprotkb:Q8N3H2|ensembl:ENSP00000369860 intact:EBI-1560194|uniprotkb:Q13036|uniprotkb:B2RBV9|ensembl:ENSP00000312709 psi-mi:mspd2_human(display_long)|uniprotkb:MOSPD2(gene name)|psi-mi:MOSPD2(display_short) psi-mi:taf7_human(display_long)|uniprotkb:Transcription initiation factor TFIID 55 kDa subunit(gene name synonym)|uniprotkb:RNA polymerase II TBP-associated factor subunit F(gene name synonym)|uniprotkb:TAF7(gene name)|psi-mi:TAF7(display_short)|uniprotkb:TAF2F(gene name synonym)|uniprotkb:TAFII55(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Di et al. (2018) pubmed:29858488|imex:IM-28178 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-25617558|imex:IM-28178-11 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001170946.1|refseq:NP_689794.1|go:"GO:0090023"(positive regulation of neutrophil chemotaxis)|go:"GO:0090026"(positive regulation of monocyte chemotaxis)|go:"GO:0140284"(endoplasmic reticulum-endosome membrane contact site)|interpro:IPR000535(Major sperm protein)|interpro:IPR001251(Cellular retinaldehyde-binding/triple function, C-terminal)|interpro:IPR008962(PapD-like)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR036273|interpro:IPR036865|mint:Q8NHP6|rcsb pdb:6TQS|rcsb pdb:6TQT|rcsb pdb:6TQU|reactome:R-HSA-6798695|reactome:R-HSA-9013405|ensembl:ENSG00000130150(gene)|ensembl:ENST00000380492(transcript)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006935"(chemotaxis)|go:"GO:0016020"(membrane)|go:"GO:0035579"(specific granule membrane)|go:"GO:0044232"(organelle membrane contact site) refseq:NP_005633.2|dip:DIP-29047N|ensembl:ENSG00000178913(gene)|ensembl:ENST00000313368(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000296"(spermine transport)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0001097"(TFIIH-class transcription factor complex binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005669"(transcription factor TFIID complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0006352"(DNA-templated transcription, initiation)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0006367"(transcription initiation from RNA polymerase II promoter)|go:"GO:0006469"(negative regulation of protein kinase activity)|go:"GO:0008134"(transcription factor binding)|go:"GO:0016251"(RNA polymerase II general transcription initiation factor activity)|go:"GO:0030520"(intracellular estrogen receptor signaling pathway)|go:"GO:0033276"(transcription factor TFTC complex)|go:"GO:0035035"(histone acetyltransferase binding)|go:"GO:0035067"(negative regulation of histone acetylation)|go:"GO:0042809"(vitamin D receptor binding)|go:"GO:0045344"(negative regulation of MHC class I biosynthetic process)|go:"GO:0045347"(negative regulation of MHC class II biosynthetic process)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046966"(thyroid hormone receptor binding)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0051123"(RNA polymerase II preinitiation complex assembly)|go:"GO:0071339"(MLL1 complex)|go:"GO:0090241"(negative regulation of histone H4 acetylation)|go:"GO:0106140"(P-TEFb complex binding)|interpro:IPR006751(TAFII55 protein conserved region)|interpro:IPR037817|rcsb pdb:4RGW|rcsb pdb:5FUR|rcsb pdb:6MZL|rcsb pdb:6MZM|rcsb pdb:7EDX|rcsb pdb:7EG7|rcsb pdb:7EG8|rcsb pdb:7EG9|rcsb pdb:7EGA|rcsb pdb:7EGB|rcsb pdb:7EGC|rcsb pdb:7EGD|rcsb pdb:7EGE|rcsb pdb:7EGH|rcsb pdb:7EGI|rcsb pdb:7EGJ|rcsb pdb:7ENA|rcsb pdb:7ENC|reactome:R-HSA-167161|reactome:R-HSA-167162|reactome:R-HSA-167172|reactome:R-HSA-674695|reactome:R-HSA-6804756|reactome:R-HSA-73776|reactome:R-HSA-73779|reactome:R-HSA-75953|reactome:R-HSA-76042 - - - figure legend:Fig. 5A, Supp. Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells) - 2020/05/21 2021/04/12 rogid:WEdwMYKpu1uQll5NXnMm4P51R4E9606 rogid:FFk04k421YC/B0n/5GXpDK9uhBU9606 rigid:1P63pNv1yn3F27gcT2OsGH/3EDQ false green fluorescent protein tag:n-n|mutation disrupting interaction strength:406-406,404-404 - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q8NHP6 uniprotkb:X1WI28 intact:EBI-2812848|uniprotkb:Q8NA83|uniprotkb:Q8N3H2|ensembl:ENSP00000369860 intact:EBI-25617651|ensembl:ENSP00000388600 psi-mi:mspd2_human(display_long)|uniprotkb:MOSPD2(gene name)|psi-mi:MOSPD2(display_short) psi-mi:x1wi28_human(display_long)|uniprotkb:RPL10(gene name)|psi-mi:RPL10(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Di et al. (2018) pubmed:29858488|imex:IM-28178 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-25617558|imex:IM-28178-11 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001170946.1|refseq:NP_689794.1|go:"GO:0090023"(positive regulation of neutrophil chemotaxis)|go:"GO:0090026"(positive regulation of monocyte chemotaxis)|go:"GO:0140284"(endoplasmic reticulum-endosome membrane contact site)|interpro:IPR000535(Major sperm protein)|interpro:IPR001251(Cellular retinaldehyde-binding/triple function, C-terminal)|interpro:IPR008962(PapD-like)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR036273|interpro:IPR036865|mint:Q8NHP6|rcsb pdb:6TQS|rcsb pdb:6TQT|rcsb pdb:6TQU|reactome:R-HSA-6798695|reactome:R-HSA-9013405|ensembl:ENSG00000130150(gene)|ensembl:ENST00000380492(transcript)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006935"(chemotaxis)|go:"GO:0016020"(membrane)|go:"GO:0035579"(specific granule membrane)|go:"GO:0044232"(organelle membrane contact site) go:"GO:0006412"(translation)|interpro:IPR001197(Ribosomal protein L10e)|interpro:IPR016180(Ribosomal protein L10e/L16)|interpro:IPR018255|interpro:IPR036920|ensembl:ENSG00000147403(gene)|ensembl:ENST00000436473(transcript)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005829"(cytosol)|go:"GO:0005840"(ribosome) - - - figure legend:Fig. 5A, Supp. Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells) - 2020/05/21 2021/04/12 rogid:WEdwMYKpu1uQll5NXnMm4P51R4E9606 rogid:vkTOPrt3yD9UD7G+PBcxNe4OAFM9606 rigid:1P63pNv1yn3F27gcT2OsGH/3EDQ false green fluorescent protein tag:n-n|mutation disrupting interaction strength:406-406,404-404 - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q8NHP6 uniprotkb:E5RHW4 intact:EBI-2812848|uniprotkb:Q8NA83|uniprotkb:Q8N3H2|ensembl:ENSP00000369860 intact:EBI-11048976|ensembl:ENSP00000429621 psi-mi:mspd2_human(display_long)|uniprotkb:MOSPD2(gene name)|psi-mi:MOSPD2(display_short) psi-mi:e5rhw4_human(display_long)|uniprotkb:ERLIN2(gene name)|psi-mi:ERLIN2(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Di et al. (2018) pubmed:29858488|imex:IM-28178 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-25617558|imex:IM-28178-11 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001170946.1|refseq:NP_689794.1|go:"GO:0090023"(positive regulation of neutrophil chemotaxis)|go:"GO:0090026"(positive regulation of monocyte chemotaxis)|go:"GO:0140284"(endoplasmic reticulum-endosome membrane contact site)|interpro:IPR000535(Major sperm protein)|interpro:IPR001251(Cellular retinaldehyde-binding/triple function, C-terminal)|interpro:IPR008962(PapD-like)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR036273|interpro:IPR036865|mint:Q8NHP6|rcsb pdb:6TQS|rcsb pdb:6TQT|rcsb pdb:6TQU|reactome:R-HSA-6798695|reactome:R-HSA-9013405|ensembl:ENSG00000130150(gene)|ensembl:ENST00000380492(transcript)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006935"(chemotaxis)|go:"GO:0016020"(membrane)|go:"GO:0035579"(specific granule membrane)|go:"GO:0044232"(organelle membrane contact site) ensembl:ENSG00000147475(gene)|ensembl:ENST00000521644(transcript)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0008202"(steroid metabolic process)|go:"GO:0016021"(integral component of membrane)|go:"GO:0031625"(ubiquitin protein ligase binding)|interpro:IPR001107(Band 7 protein)|interpro:IPR033294|interpro:IPR036013 - - - figure legend:Fig. 5A, Supp. Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells) - 2020/05/21 2021/04/12 rogid:WEdwMYKpu1uQll5NXnMm4P51R4E9606 rogid:ssonN7BaEQqdwbmlcwelkocpS/k9606 rigid:1P63pNv1yn3F27gcT2OsGH/3EDQ false green fluorescent protein tag:n-n|mutation disrupting interaction strength:406-406,404-404 - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q8NHP6 uniprotkb:P50991 intact:EBI-2812848|uniprotkb:Q8NA83|uniprotkb:Q8N3H2|ensembl:ENSP00000369860 intact:EBI-356876|uniprotkb:O14870|uniprotkb:Q96C51|uniprotkb:Q53QP9|uniprotkb:B2R6I3|uniprotkb:B7Z8B1|uniprotkb:F5H5W3|ensembl:ENSP00000377958 psi-mi:mspd2_human(display_long)|uniprotkb:MOSPD2(gene name)|psi-mi:MOSPD2(display_short) psi-mi:tcpd_human(display_long)|uniprotkb:CCT4(gene name)|psi-mi:CCT4(display_short)|uniprotkb:CCTD(gene name synonym)|uniprotkb:SRB(gene name synonym)|uniprotkb:CCT-delta(gene name synonym)|uniprotkb:Stimulator of TAR RNA-binding(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Di et al. (2018) pubmed:29858488|imex:IM-28178 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-25617558|imex:IM-28178-11 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001170946.1|refseq:NP_689794.1|go:"GO:0090023"(positive regulation of neutrophil chemotaxis)|go:"GO:0090026"(positive regulation of monocyte chemotaxis)|go:"GO:0140284"(endoplasmic reticulum-endosome membrane contact site)|interpro:IPR000535(Major sperm protein)|interpro:IPR001251(Cellular retinaldehyde-binding/triple function, C-terminal)|interpro:IPR008962(PapD-like)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR036273|interpro:IPR036865|mint:Q8NHP6|rcsb pdb:6TQS|rcsb pdb:6TQT|rcsb pdb:6TQU|reactome:R-HSA-6798695|reactome:R-HSA-9013405|ensembl:ENSG00000130150(gene)|ensembl:ENST00000380492(transcript)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006935"(chemotaxis)|go:"GO:0016020"(membrane)|go:"GO:0035579"(specific granule membrane)|go:"GO:0044232"(organelle membrane contact site) refseq:NP_006421.2|refseq:NP_001243650.1|dip:DIP-32971N|ensembl:ENSG00000115484(gene)|ensembl:ENST00000394440(transcript)|go:"GO:0002199"(zona pellucida receptor complex)|go:"GO:0003723"(RNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005832"(chaperonin-containing T-complex)|go:"GO:0005874"(microtubule)|go:"GO:0006457"(protein folding)|go:"GO:0007339"(binding of sperm to zona pellucida)|go:"GO:0032212"(positive regulation of telomere maintenance via telomerase)|go:"GO:0042470"(melanosome)|go:"GO:0042995"(cell projection)|go:"GO:0044183"(protein folding chaperone)|go:"GO:0044297"(cell body)|go:"GO:0050821"(protein stabilization)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0051973"(positive regulation of telomerase activity)|go:"GO:0070062"(extracellular exosome)|go:"GO:0090666"(scaRNA localization to Cajal body)|go:"GO:1901998"(toxin transport)|go:"GO:1904851"(positive regulation of establishment of protein localization to telomere)|go:"GO:1904871"(positive regulation of protein localization to Cajal body)|go:"GO:1904874"(positive regulation of telomerase RNA localization to Cajal body)|interpro:IPR002194(Chaperonin TCP-1, conserved site)|interpro:IPR002423(Chaperonin Cpn60/TCP-1)|interpro:IPR012717(T-complex protein 1, delta subunit)|interpro:IPR027409|interpro:IPR027410|interpro:IPR027413|mint:P50991|rcsb pdb:6NR8|rcsb pdb:6NR9|rcsb pdb:6NRA|rcsb pdb:6NRB|rcsb pdb:6NRC|rcsb pdb:6NRD|rcsb pdb:6QB8|rcsb pdb:7LUM|rcsb pdb:7LUP|reactome:R-HSA-389957|reactome:R-HSA-389960|reactome:R-HSA-390450|reactome:R-HSA-390471|reactome:R-HSA-5620922|reactome:R-HSA-6814122|interpro:IPR017998 - - - figure legend:Fig. 5A, Supp. Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells) - 2020/05/21 2021/04/12 rogid:WEdwMYKpu1uQll5NXnMm4P51R4E9606 rogid:Erg8Zzajt1WbrByS9LR4NAhZrXM9606 rigid:1P63pNv1yn3F27gcT2OsGH/3EDQ false green fluorescent protein tag:n-n|mutation disrupting interaction strength:406-406,404-404 - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q8NHP6 uniprotkb:O15155 intact:EBI-2812848|uniprotkb:Q8NA83|uniprotkb:Q8N3H2|ensembl:ENSP00000369860 intact:EBI-749204|uniprotkb:Q96EA0|ensembl:ENSP00000222547 psi-mi:mspd2_human(display_long)|uniprotkb:MOSPD2(gene name)|psi-mi:MOSPD2(display_short) psi-mi:bet1_human(display_long)|uniprotkb:Golgi vesicular membrane-trafficking protein p18(gene name synonym)|uniprotkb:BET1(gene name)|psi-mi:BET1(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Di et al. (2018) pubmed:29858488|imex:IM-28178 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-25617558|imex:IM-28178-11 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001170946.1|refseq:NP_689794.1|go:"GO:0090023"(positive regulation of neutrophil chemotaxis)|go:"GO:0090026"(positive regulation of monocyte chemotaxis)|go:"GO:0140284"(endoplasmic reticulum-endosome membrane contact site)|interpro:IPR000535(Major sperm protein)|interpro:IPR001251(Cellular retinaldehyde-binding/triple function, C-terminal)|interpro:IPR008962(PapD-like)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR036273|interpro:IPR036865|mint:Q8NHP6|rcsb pdb:6TQS|rcsb pdb:6TQT|rcsb pdb:6TQU|reactome:R-HSA-6798695|reactome:R-HSA-9013405|ensembl:ENSG00000130150(gene)|ensembl:ENST00000380492(transcript)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006935"(chemotaxis)|go:"GO:0016020"(membrane)|go:"GO:0035579"(specific granule membrane)|go:"GO:0044232"(organelle membrane contact site) refseq:NP_005859.1|refseq:NP_001304668.1|ensembl:ENSG00000105829(gene)|ensembl:ENST00000222547(transcript)|go:"GO:0000138"(Golgi trans cisterna)|go:"GO:0000139"(Golgi membrane)|go:"GO:0005484"(SNAP receptor activity)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0015031"(protein transport)|go:"GO:0016020"(membrane)|go:"GO:0030133"(transport vesicle)|go:"GO:0030173"(integral component of Golgi membrane)|go:"GO:0033116"(endoplasmic reticulum-Golgi intermediate compartment membrane)|go:"GO:0048280"(vesicle fusion with Golgi apparatus)|interpro:IPR000727(Target SNARE coiled-coil region)|interpro:IPR039897|interpro:IPR039899|rcsb pdb:3EGX|reactome:R-HSA-204005|reactome:R-HSA-6807878|go:"GO:0031201"(SNARE complex) - - - figure legend:Fig. 5A, Supp. Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells) - 2020/05/21 2021/04/12 rogid:WEdwMYKpu1uQll5NXnMm4P51R4E9606 rogid:q+HguYhGwObsWqPGNyIVXf/YHO49606 rigid:1P63pNv1yn3F27gcT2OsGH/3EDQ false green fluorescent protein tag:n-n|mutation disrupting interaction strength:406-406,404-404 - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q8NHP6 uniprotkb:V9GY01 intact:EBI-2812848|uniprotkb:Q8NA83|uniprotkb:Q8N3H2|ensembl:ENSP00000369860 intact:EBI-25617634|ensembl:ENSP00000476263 psi-mi:mspd2_human(display_long)|uniprotkb:MOSPD2(gene name)|psi-mi:MOSPD2(display_short) psi-mi:v9gy01_human(display_long)|uniprotkb:KNSTRN(gene name)|psi-mi:KNSTRN(display_short)|uniprotkb:C15orf23(gene name synonym)|uniprotkb:hCG_38973(orf name) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Di et al. (2018) pubmed:29858488|imex:IM-28178 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-25617558|imex:IM-28178-11 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001170946.1|refseq:NP_689794.1|go:"GO:0090023"(positive regulation of neutrophil chemotaxis)|go:"GO:0090026"(positive regulation of monocyte chemotaxis)|go:"GO:0140284"(endoplasmic reticulum-endosome membrane contact site)|interpro:IPR000535(Major sperm protein)|interpro:IPR001251(Cellular retinaldehyde-binding/triple function, C-terminal)|interpro:IPR008962(PapD-like)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR036273|interpro:IPR036865|mint:Q8NHP6|rcsb pdb:6TQS|rcsb pdb:6TQT|rcsb pdb:6TQU|reactome:R-HSA-6798695|reactome:R-HSA-9013405|ensembl:ENSG00000130150(gene)|ensembl:ENST00000380492(transcript)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006935"(chemotaxis)|go:"GO:0016020"(membrane)|go:"GO:0035579"(specific granule membrane)|go:"GO:0044232"(organelle membrane contact site) ensembl:ENSG00000128944(gene)|ensembl:ENST00000608100(transcript)|go:"GO:0000776"(kinetochore)|go:"GO:0005886"(plasma membrane)|go:"GO:0007051"(spindle organization)|go:"GO:0007059"(chromosome segregation)|go:"GO:0034451"(centriolar satellite)|go:"GO:0051988"(regulation of attachment of spindle microtubules to kinetochore)|go:"GO:0072686"(mitotic spindle)|interpro:IPR033373 - - - figure legend:Fig. 5A, Supp. Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells) - 2020/05/21 2021/04/12 rogid:WEdwMYKpu1uQll5NXnMm4P51R4E9606 rogid:L8VVgiOFPva/tUBddmAtFHeo2NY9606 rigid:1P63pNv1yn3F27gcT2OsGH/3EDQ false green fluorescent protein tag:n-n|mutation disrupting interaction strength:406-406,404-404 - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q8NHP6 uniprotkb:P20042 intact:EBI-2812848|uniprotkb:Q8NA83|uniprotkb:Q8N3H2|ensembl:ENSP00000369860 intact:EBI-711977|ensembl:ENSP00000364119|uniprotkb:Q9BVU0|uniprotkb:Q9UJE4 psi-mi:mspd2_human(display_long)|uniprotkb:MOSPD2(gene name)|psi-mi:MOSPD2(display_short) psi-mi:if2b_human(display_long)|uniprotkb:Eukaryotic translation initiation factor 2 subunit beta(gene name synonym)|uniprotkb:EIF2S2(gene name)|psi-mi:EIF2S2(display_short)|uniprotkb:EIF2B(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Di et al. (2018) pubmed:29858488|imex:IM-28178 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-25617558|imex:IM-28178-11 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001170946.1|refseq:NP_689794.1|go:"GO:0090023"(positive regulation of neutrophil chemotaxis)|go:"GO:0090026"(positive regulation of monocyte chemotaxis)|go:"GO:0140284"(endoplasmic reticulum-endosome membrane contact site)|interpro:IPR000535(Major sperm protein)|interpro:IPR001251(Cellular retinaldehyde-binding/triple function, C-terminal)|interpro:IPR008962(PapD-like)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR036273|interpro:IPR036865|mint:Q8NHP6|rcsb pdb:6TQS|rcsb pdb:6TQT|rcsb pdb:6TQU|reactome:R-HSA-6798695|reactome:R-HSA-9013405|ensembl:ENSG00000130150(gene)|ensembl:ENST00000380492(transcript)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006935"(chemotaxis)|go:"GO:0016020"(membrane)|go:"GO:0035579"(specific granule membrane)|go:"GO:0044232"(organelle membrane contact site) ensembl:ENSG00000125977(gene)|ensembl:ENST00000374980(transcript)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0001731"(formation of translation preinitiation complex)|go:"GO:0001732"(formation of cytoplasmic translation initiation complex)|go:"GO:0002176"(male germ cell proliferation)|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0003743"(translation initiation factor activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005850"(eukaryotic translation initiation factor 2 complex)|go:"GO:0008135"(translation factor activity, RNA binding)|go:"GO:0008584"(male gonad development)|go:"GO:0031369"(translation initiation factor binding)|go:"GO:0046872"(metal ion binding)|interpro:IPR002735(Translation initiation factor IF2/IF5)|interpro:IPR016189(Translation initiation factor IF2/IF5, N-terminal)|interpro:IPR016190(Translation initiation factor IF2/IF5, zinc-binding)|mint:P20042|rcsb pdb:6K71|rcsb pdb:6K72|rcsb pdb:6YBV|rcsb pdb:6ZMW|rcsb pdb:6ZP4|rcsb pdb:7A09|rcsb pdb:7D43|reactome:R-HSA-156827|reactome:R-HSA-381042|reactome:R-HSA-382556|reactome:R-HSA-72649|reactome:R-HSA-72695|reactome:R-HSA-72702|reactome:R-HSA-72706|reactome:R-HSA-72731|reactome:R-HSA-9633012|reactome:R-HSA-9648895|refseq:NP_003899.2 - - - figure legend:Fig. 5A, Supp. Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells) - 2020/05/21 2021/04/12 rogid:WEdwMYKpu1uQll5NXnMm4P51R4E9606 rogid:64ZkCKZ5jRT6MEm9RK4AynY2ga49606 rigid:1P63pNv1yn3F27gcT2OsGH/3EDQ false green fluorescent protein tag:n-n|mutation disrupting interaction strength:406-406,404-404 - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q8NHP6 uniprotkb:P42167 intact:EBI-2812848|uniprotkb:Q8NA83|uniprotkb:Q8N3H2|ensembl:ENSP00000369860 intact:EBI-455283|uniprotkb:Q14861|ensembl:ENSP00000450627|uniprotkb:A2T926 psi-mi:mspd2_human(display_long)|uniprotkb:MOSPD2(gene name)|psi-mi:MOSPD2(display_short) psi-mi:lap2b_human(display_long)|uniprotkb:Thymopoietin-related peptide isoforms beta/gamma(gene name synonym)|uniprotkb:Thymopoietin, isoforms beta/gamma(gene name synonym)|uniprotkb:TMPO(gene name)|psi-mi:TMPO(display_short)|uniprotkb:LAP2(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Di et al. (2018) pubmed:29858488|imex:IM-28178 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-25617558|imex:IM-28178-11 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001170946.1|refseq:NP_689794.1|go:"GO:0090023"(positive regulation of neutrophil chemotaxis)|go:"GO:0090026"(positive regulation of monocyte chemotaxis)|go:"GO:0140284"(endoplasmic reticulum-endosome membrane contact site)|interpro:IPR000535(Major sperm protein)|interpro:IPR001251(Cellular retinaldehyde-binding/triple function, C-terminal)|interpro:IPR008962(PapD-like)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR036273|interpro:IPR036865|mint:Q8NHP6|rcsb pdb:6TQS|rcsb pdb:6TQT|rcsb pdb:6TQU|reactome:R-HSA-6798695|reactome:R-HSA-9013405|ensembl:ENSG00000130150(gene)|ensembl:ENST00000380492(transcript)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006935"(chemotaxis)|go:"GO:0016020"(membrane)|go:"GO:0035579"(specific granule membrane)|go:"GO:0044232"(organelle membrane contact site) refseq:NP_001294904.1|refseq:NP_001027454.1|refseq:NP_001027455.1|ensembl:ENSG00000120802(gene)|ensembl:ENST00000556029(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0005521"(lamin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005637"(nuclear inner membrane)|go:"GO:0005829"(cytosol)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0031965"(nuclear membrane)|interpro:IPR003887(Lamino-associated polypeptide 2/emerin)|interpro:IPR011015(LEM-like fold)|interpro:IPR013146(Thymopoietin LEM)|mint:P42167|reactome:R-HSA-2980766|reactome:R-HSA-2995383|reactome:R-HSA-4419969|dip:DIP-43686N|reactome:R-HSA-8980692|reactome:R-HSA-9013106|reactome:R-HSA-9013148|reactome:R-HSA-9013149|reactome:R-HSA-9013404|reactome:R-HSA-9013405|reactome:R-HSA-9013408|reactome:R-HSA-9013409|reactome:R-HSA-9013423|reactome:R-HSA-9035034 - - - figure legend:Fig. 5A, Supp. Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells) - 2020/05/21 2021/04/12 rogid:WEdwMYKpu1uQll5NXnMm4P51R4E9606 rogid:S2mYrSugx0Ms4vhw/vYYH/SthOw9606 rigid:1P63pNv1yn3F27gcT2OsGH/3EDQ false green fluorescent protein tag:n-n|mutation disrupting interaction strength:406-406,404-404 - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q8NHP6 uniprotkb:P20908 intact:EBI-2812848|uniprotkb:Q8NA83|uniprotkb:Q8N3H2|ensembl:ENSP00000369860 intact:EBI-2464511|uniprotkb:Q15094|uniprotkb:Q5SUX4|uniprotkb:A0A087WXW9|ensembl:ENSP00000360882 psi-mi:mspd2_human(display_long)|uniprotkb:MOSPD2(gene name)|psi-mi:MOSPD2(display_short) psi-mi:co5a1_human(display_long)|uniprotkb:COL5A1(gene name)|psi-mi:COL5A1(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Di et al. (2018) pubmed:29858488|imex:IM-28178 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-25617558|imex:IM-28178-11 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001170946.1|refseq:NP_689794.1|go:"GO:0090023"(positive regulation of neutrophil chemotaxis)|go:"GO:0090026"(positive regulation of monocyte chemotaxis)|go:"GO:0140284"(endoplasmic reticulum-endosome membrane contact site)|interpro:IPR000535(Major sperm protein)|interpro:IPR001251(Cellular retinaldehyde-binding/triple function, C-terminal)|interpro:IPR008962(PapD-like)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR036273|interpro:IPR036865|mint:Q8NHP6|rcsb pdb:6TQS|rcsb pdb:6TQT|rcsb pdb:6TQU|reactome:R-HSA-6798695|reactome:R-HSA-9013405|ensembl:ENSG00000130150(gene)|ensembl:ENST00000380492(transcript)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006935"(chemotaxis)|go:"GO:0016020"(membrane)|go:"GO:0035579"(specific granule membrane)|go:"GO:0044232"(organelle membrane contact site) refseq:NP_000084.3|go:"GO:0043394"(proteoglycan binding)|go:"GO:0043588"(skin development)|go:"GO:0045112"(integrin biosynthetic process)|go:"GO:0046872"(metal ion binding)|go:"GO:0048407"(platelet-derived growth factor binding)|go:"GO:0048592"(eye morphogenesis)|go:"GO:0051128"(regulation of cellular component organization)|go:"GO:0062023"(collagen-containing extracellular matrix)|go:"GO:0097435"(supramolecular fiber organization)|go:"GO:1903225"(negative regulation of endodermal cell differentiation)|interpro:IPR000885(Fibrillar collagen, C-terminal)|interpro:IPR001791(Laminin G)|interpro:IPR008160(Collagen triple helix repeat)|interpro:IPR013320(Concanavalin A-like lectin/glucanase, subgroup)|rcsb pdb:1A89|rcsb pdb:1A9A|reactome:R-HSA-1442490|reactome:R-HSA-1474244|reactome:R-HSA-1650814|reactome:R-HSA-186797|reactome:R-HSA-2022090|reactome:R-HSA-216083|reactome:R-HSA-3000170|reactome:R-HSA-3000171|reactome:R-HSA-3000178|reactome:R-HSA-419037|reactome:R-HSA-8874081|reactome:R-HSA-8948216|ensembl:ENSG00000130635(gene)|ensembl:ENST00000371817(transcript)|go:"GO:0001568"(blood vessel development)|go:"GO:0003007"(heart morphogenesis)|go:"GO:0005178"(integrin binding)|go:"GO:0005201"(extracellular matrix structural constituent)|go:"GO:0005576"(extracellular region)|go:"GO:0005588"(collagen type V trimer)|go:"GO:0005604"(basement membrane)|go:"GO:0005615"(extracellular space)|go:"GO:0005788"(endoplasmic reticulum lumen)|go:"GO:0007155"(cell adhesion)|go:"GO:0008201"(heparin binding)|go:"GO:0016477"(cell migration)|go:"GO:0030020"(extracellular matrix structural constituent conferring tensile strength)|go:"GO:0030198"(extracellular matrix organization)|go:"GO:0030199"(collagen fibril organization)|go:"GO:0031012"(extracellular matrix)|go:"GO:0032964"(collagen biosynthetic process)|go:"GO:0035313"(wound healing, spreading of epidermal cells)|go:"GO:0035989"(tendon development) - - - figure legend:Fig. 5A, Supp. Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells) - 2020/05/21 2021/04/12 rogid:WEdwMYKpu1uQll5NXnMm4P51R4E9606 rogid:VuIbevtKCbDH6f3KwEFMOe9nzKg9606 rigid:1P63pNv1yn3F27gcT2OsGH/3EDQ false green fluorescent protein tag:n-n|mutation disrupting interaction strength:406-406,404-404 - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q8NHP6 uniprotkb:G3V576 intact:EBI-2812848|uniprotkb:Q8NA83|uniprotkb:Q8N3H2|ensembl:ENSP00000369860 intact:EBI-25617600|ensembl:ENSP00000451187|ensembl:ENSP00000452214 psi-mi:mspd2_human(display_long)|uniprotkb:MOSPD2(gene name)|psi-mi:MOSPD2(display_short) psi-mi:g3v576_human(display_long)|uniprotkb:HNRNPC(gene name)|psi-mi:HNRNPC(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Di et al. (2018) pubmed:29858488|imex:IM-28178 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-25617558|imex:IM-28178-11 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001170946.1|refseq:NP_689794.1|go:"GO:0090023"(positive regulation of neutrophil chemotaxis)|go:"GO:0090026"(positive regulation of monocyte chemotaxis)|go:"GO:0140284"(endoplasmic reticulum-endosome membrane contact site)|interpro:IPR000535(Major sperm protein)|interpro:IPR001251(Cellular retinaldehyde-binding/triple function, C-terminal)|interpro:IPR008962(PapD-like)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR036273|interpro:IPR036865|mint:Q8NHP6|rcsb pdb:6TQS|rcsb pdb:6TQT|rcsb pdb:6TQU|reactome:R-HSA-6798695|reactome:R-HSA-9013405|ensembl:ENSG00000130150(gene)|ensembl:ENST00000380492(transcript)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006935"(chemotaxis)|go:"GO:0016020"(membrane)|go:"GO:0035579"(specific granule membrane)|go:"GO:0044232"(organelle membrane contact site) ensembl:ENSG00000092199(gene)|ensembl:ENST00000556142(transcript)|ensembl:ENST00000556513(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0005654"(nucleoplasm)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR035979 - - - figure legend:Fig. 5A, Supp. Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells) - 2020/05/21 2021/04/12 rogid:WEdwMYKpu1uQll5NXnMm4P51R4E9606 rogid:dnTIlr/G6tFjymxiClOmldmdevQ9606 rigid:1P63pNv1yn3F27gcT2OsGH/3EDQ false green fluorescent protein tag:n-n|mutation disrupting interaction strength:406-406,404-404 - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q8NHP6 uniprotkb:P17706 intact:EBI-2812848|uniprotkb:Q8NA83|uniprotkb:Q8N3H2|ensembl:ENSP00000369860 intact:EBI-984930|uniprotkb:K7ENG3|uniprotkb:Q96HR2|ensembl:ENSP00000311857|uniprotkb:A8MXU3|uniprotkb:Q96AU5|uniprotkb:A8K955 psi-mi:mspd2_human(display_long)|uniprotkb:MOSPD2(gene name)|psi-mi:MOSPD2(display_short) psi-mi:ptn2_human(display_long)|uniprotkb:T-cell protein-tyrosine phosphatase(gene name synonym)|uniprotkb:PTPN2(gene name)|psi-mi:PTPN2(display_short)|uniprotkb:PTPT(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Di et al. (2018) pubmed:29858488|imex:IM-28178 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-25617558|imex:IM-28178-11 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001170946.1|refseq:NP_689794.1|go:"GO:0090023"(positive regulation of neutrophil chemotaxis)|go:"GO:0090026"(positive regulation of monocyte chemotaxis)|go:"GO:0140284"(endoplasmic reticulum-endosome membrane contact site)|interpro:IPR000535(Major sperm protein)|interpro:IPR001251(Cellular retinaldehyde-binding/triple function, C-terminal)|interpro:IPR008962(PapD-like)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR036273|interpro:IPR036865|mint:Q8NHP6|rcsb pdb:6TQS|rcsb pdb:6TQT|rcsb pdb:6TQU|reactome:R-HSA-6798695|reactome:R-HSA-9013405|ensembl:ENSG00000130150(gene)|ensembl:ENST00000380492(transcript)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006935"(chemotaxis)|go:"GO:0016020"(membrane)|go:"GO:0035579"(specific granule membrane)|go:"GO:0044232"(organelle membrane contact site) ensembl:ENSG00000175354(gene)|ensembl:ENST00000309660(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0004725"(protein tyrosine phosphatase activity)|go:"GO:0004726"(non-membrane spanning protein tyrosine phosphatase activity)|go:"GO:0005178"(integrin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005793"(endoplasmic reticulum-Golgi intermediate compartment)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0008286"(insulin receptor signaling pathway)|go:"GO:0010804"(negative regulation of tumor necrosis factor-mediated signaling pathway)|go:"GO:0010888"(negative regulation of lipid storage)|go:"GO:0019901"(protein kinase binding)|go:"GO:0019905"(syntaxin binding)|go:"GO:0030183"(B cell differentiation)|go:"GO:0030217"(T cell differentiation)|go:"GO:0030218"(erythrocyte differentiation)|go:"GO:0030971"(receptor tyrosine kinase binding)|go:"GO:0035335"(peptidyl-tyrosine dephosphorylation)|go:"GO:0042059"(negative regulation of epidermal growth factor receptor signaling pathway)|go:"GO:0042532"(negative regulation of tyrosine phosphorylation of STAT protein)|go:"GO:0042593"(glucose homeostasis)|go:"GO:0045650"(negative regulation of macrophage differentiation)|go:"GO:0045722"(positive regulation of gluconeogenesis)|go:"GO:0046627"(negative regulation of insulin receptor signaling pathway)|go:"GO:0050728"(negative regulation of inflammatory response)|go:"GO:0050860"(negative regulation of T cell receptor signaling pathway)|go:"GO:0050922"(negative regulation of chemotaxis)|go:"GO:0060334"(regulation of interferon-gamma-mediated signaling pathway)|go:"GO:0060336"(negative regulation of interferon-gamma-mediated signaling pathway)|go:"GO:0060339"(negative regulation of type I interferon-mediated signaling pathway)|go:"GO:0061099"(negative regulation of protein tyrosine kinase activity)|go:"GO:0070104"(negative regulation of interleukin-6-mediated signaling pathway)|go:"GO:0070373"(negative regulation of ERK1 and ERK2 cascade)|go:"GO:0097677"(STAT family protein binding)|go:"GO:1902202"(regulation of hepatocyte growth factor receptor signaling pathway)|go:"GO:1902206"(negative regulation of interleukin-2-mediated signaling pathway)|go:"GO:1902215"(negative regulation of interleukin-4-mediated signaling pathway)|go:"GO:1902227"(negative regulation of macrophage colony-stimulating factor signaling pathway)|go:"GO:1902233"(negative regulation of positive thymic T cell selection)|go:"GO:1902237"(positive regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway)|go:"GO:1903899"(positive regulation of PERK-mediated unfolded protein response)|go:"GO:2000587"(negative regulation of platelet-derived growth factor receptor-beta signaling pathway)|interpro:IPR000242(Protein-tyrosine phosphatase, receptor/non-receptor type)|interpro:IPR000387(Protein-tyrosine phosphatase)|interpro:IPR003595(Protein-tyrosine phosphatase, catalytic)|interpro:IPR012265(Protein-tyrosine phosphatase, non-receptor type-1, -2)|interpro:IPR016130(Protein-tyrosine phosphatase, active site)|interpro:IPR029021|mint:P17706|rcsb pdb:1L8K|reactome:R-HSA-877312|reactome:R-HSA-9008059|reactome:R-HSA-6807004|refseq:NP_001193942.1|refseq:NP_002819.2|refseq:NP_536347.1|refseq:NP_536348.1 - - - figure legend:Fig. 5A, Supp. Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells) - 2020/05/21 2021/04/12 rogid:WEdwMYKpu1uQll5NXnMm4P51R4E9606 rogid:z8pewLjrIdVPp07u6Rz7xfyn76k9606 rigid:1P63pNv1yn3F27gcT2OsGH/3EDQ false green fluorescent protein tag:n-n|mutation disrupting interaction strength:406-406,404-404 - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q8NHP6 uniprotkb:P42704 intact:EBI-2812848|uniprotkb:Q8NA83|uniprotkb:Q8N3H2|ensembl:ENSP00000369860 intact:EBI-1050853|uniprotkb:A0PJE3|uniprotkb:A8K1V1|uniprotkb:Q53PC0|uniprotkb:Q53QN7|uniprotkb:Q96D84|uniprotkb:Q6ZUD8|uniprotkb:Q7Z7A6|ensembl:ENSP00000260665 psi-mi:mspd2_human(display_long)|uniprotkb:MOSPD2(gene name)|psi-mi:MOSPD2(display_short) psi-mi:lpprc_human(display_long)|uniprotkb:130 kDa leucine-rich protein(gene name synonym)|uniprotkb:GP130(gene name synonym)|uniprotkb:LRPPRC(gene name)|psi-mi:LRPPRC(display_short)|uniprotkb:LRP130(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Di et al. (2018) pubmed:29858488|imex:IM-28178 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-25617558|imex:IM-28178-11 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001170946.1|refseq:NP_689794.1|go:"GO:0090023"(positive regulation of neutrophil chemotaxis)|go:"GO:0090026"(positive regulation of monocyte chemotaxis)|go:"GO:0140284"(endoplasmic reticulum-endosome membrane contact site)|interpro:IPR000535(Major sperm protein)|interpro:IPR001251(Cellular retinaldehyde-binding/triple function, C-terminal)|interpro:IPR008962(PapD-like)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR036273|interpro:IPR036865|mint:Q8NHP6|rcsb pdb:6TQS|rcsb pdb:6TQT|rcsb pdb:6TQU|reactome:R-HSA-6798695|reactome:R-HSA-9013405|ensembl:ENSG00000130150(gene)|ensembl:ENST00000380492(transcript)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006935"(chemotaxis)|go:"GO:0016020"(membrane)|go:"GO:0035579"(specific granule membrane)|go:"GO:0044232"(organelle membrane contact site) refseq:NP_573566.2|ensembl:ENSG00000138095(gene)|ensembl:ENST00000260665(transcript)|go:"GO:0000794"(condensed nuclear chromosome)|go:"GO:0000961"(negative regulation of mitochondrial RNA catabolic process)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005637"(nuclear inner membrane)|go:"GO:0005640"(nuclear outer membrane)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005874"(microtubule)|go:"GO:0008017"(microtubule binding)|go:"GO:0016020"(membrane)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0042645"(mitochondrial nucleoid)|go:"GO:0047497"(mitochondrion transport along microtubule)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0048487"(beta-tubulin binding)|go:"GO:0051028"(mRNA transport)|go:"GO:0070129"(regulation of mitochondrial translation)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR002885(Pentatricopeptide repeat)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR033443|interpro:IPR033490|mint:P42704|reactome:R-HSA-5628897|reactome:R-HSA-611105|reactome:R-HSA-9707564|dip:DIP-27543N - - - figure legend:Fig. 5A, Supp. Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells) - 2020/05/21 2021/04/12 rogid:WEdwMYKpu1uQll5NXnMm4P51R4E9606 rogid:U0ERiW4agkBDQ7iWXWgRQxhozkg9606 rigid:1P63pNv1yn3F27gcT2OsGH/3EDQ false green fluorescent protein tag:n-n|mutation disrupting interaction strength:406-406,404-404 - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q8NHP6 uniprotkb:Q9BXW6 intact:EBI-2812848|uniprotkb:Q8NA83|uniprotkb:Q8N3H2|ensembl:ENSP00000369860 intact:EBI-765918|uniprotkb:Q9BZF5|uniprotkb:Q9NW87|uniprotkb:B7Z7D3|ensembl:ENSP00000320291 psi-mi:mspd2_human(display_long)|uniprotkb:MOSPD2(gene name)|psi-mi:MOSPD2(display_short) psi-mi:osbl1_human(display_long)|uniprotkb:OSBPL1A(gene name)|psi-mi:OSBPL1A(display_short)|uniprotkb:ORP1(gene name synonym)|uniprotkb:OSBP8(gene name synonym)|uniprotkb:OSBPL1(gene name synonym)|uniprotkb:OSBPL1B(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Di et al. (2018) pubmed:29858488|imex:IM-28178 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-25617558|imex:IM-28178-11 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001170946.1|refseq:NP_689794.1|go:"GO:0090023"(positive regulation of neutrophil chemotaxis)|go:"GO:0090026"(positive regulation of monocyte chemotaxis)|go:"GO:0140284"(endoplasmic reticulum-endosome membrane contact site)|interpro:IPR000535(Major sperm protein)|interpro:IPR001251(Cellular retinaldehyde-binding/triple function, C-terminal)|interpro:IPR008962(PapD-like)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR036273|interpro:IPR036865|mint:Q8NHP6|rcsb pdb:6TQS|rcsb pdb:6TQT|rcsb pdb:6TQU|reactome:R-HSA-6798695|reactome:R-HSA-9013405|ensembl:ENSG00000130150(gene)|ensembl:ENST00000380492(transcript)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006935"(chemotaxis)|go:"GO:0016020"(membrane)|go:"GO:0035579"(specific granule membrane)|go:"GO:0044232"(organelle membrane contact site) refseq:NP_001229437.1|refseq:NP_060500.3|refseq:NP_542164.2|refseq:XP_016881022.1|ensembl:ENSG00000141447(gene)|ensembl:ENST00000319481(transcript)|go:"GO:0005543"(phospholipid binding)|go:"GO:0005768"(endosome)|go:"GO:0005770"(late endosome)|go:"GO:0005829"(cytosol)|go:"GO:0006699"(bile acid biosynthetic process)|go:"GO:0008203"(cholesterol metabolic process)|go:"GO:0015248"(sterol transporter activity)|go:"GO:0015485"(cholesterol binding)|go:"GO:0016020"(membrane)|go:"GO:0016192"(vesicle-mediated transport)|go:"GO:0032934"(sterol binding)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0044232"(organelle membrane contact site)|go:"GO:0070062"(extracellular exosome)|interpro:IPR000648(Oxysterol-binding protein)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR002110(Ankyrin)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR018494|interpro:IPR020683|interpro:IPR036770|interpro:IPR037239|mint:Q9BXW6|rcsb pdb:5ZM5|rcsb pdb:5ZM6|rcsb pdb:5ZM7|rcsb pdb:6IYB|rcsb pdb:6TQS|reactome:R-HSA-192105|reactome:R-HSA-2132295|refseq:XP_016881023.1 - - - figure legend:Fig. 5A, Supp. Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells) - 2020/05/21 2021/04/12 rogid:WEdwMYKpu1uQll5NXnMm4P51R4E9606 rogid:IaZi6kaj9t0aU94PF/XOaxH1dNA9606 rigid:1P63pNv1yn3F27gcT2OsGH/3EDQ false green fluorescent protein tag:n-n|mutation disrupting interaction strength:406-406,404-404 - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q8NHP6 uniprotkb:P08670 intact:EBI-2812848|uniprotkb:Q8NA83|uniprotkb:Q8N3H2|ensembl:ENSP00000369860 intact:EBI-353844|uniprotkb:Q15867|uniprotkb:Q15868|uniprotkb:Q15869|uniprotkb:Q548L2|uniprotkb:Q6LER9|uniprotkb:Q8N850|uniprotkb:Q96ML2|uniprotkb:Q9NTM3|uniprotkb:B0YJC2|intact:EBI-3442369|uniprotkb:D3DRU4|ensembl:ENSP00000224237|ensembl:ENSP00000446007 psi-mi:mspd2_human(display_long)|uniprotkb:MOSPD2(gene name)|psi-mi:MOSPD2(display_short) psi-mi:vime_human(display_long)|uniprotkb:VIM(gene name)|psi-mi:VIM(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Di et al. (2018) pubmed:29858488|imex:IM-28178 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-25617558|imex:IM-28178-11 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001170946.1|refseq:NP_689794.1|go:"GO:0090023"(positive regulation of neutrophil chemotaxis)|go:"GO:0090026"(positive regulation of monocyte chemotaxis)|go:"GO:0140284"(endoplasmic reticulum-endosome membrane contact site)|interpro:IPR000535(Major sperm protein)|interpro:IPR001251(Cellular retinaldehyde-binding/triple function, C-terminal)|interpro:IPR008962(PapD-like)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR036273|interpro:IPR036865|mint:Q8NHP6|rcsb pdb:6TQS|rcsb pdb:6TQT|rcsb pdb:6TQU|reactome:R-HSA-6798695|reactome:R-HSA-9013405|ensembl:ENSG00000130150(gene)|ensembl:ENST00000380492(transcript)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006935"(chemotaxis)|go:"GO:0016020"(membrane)|go:"GO:0035579"(specific granule membrane)|go:"GO:0044232"(organelle membrane contact site) refseq:NP_003371.2|ensembl:ENSG00000026025(gene)|ensembl:ENST00000224237(transcript)|ensembl:ENST00000544301(transcript)|go:"GO:0003725"(double-stranded RNA binding)|go:"GO:0005200"(structural constituent of cytoskeleton)|go:"GO:0005212"(structural constituent of eye lens)|go:"GO:0005737"(cytoplasm)|go:"GO:0005777"(peroxisome)|go:"GO:0005815"(microtubule organizing center)|go:"GO:0005829"(cytosol)|go:"GO:0005844"(polysome)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005882"(intermediate filament)|go:"GO:0005886"(plasma membrane)|go:"GO:0005925"(focal adhesion)|go:"GO:0010977"(negative regulation of neuron projection development)|go:"GO:0014002"(astrocyte development)|go:"GO:0016363"(nuclear matrix)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0031252"(cell leading edge)|go:"GO:0032967"(positive regulation of collagen biosynthetic process)|go:"GO:0042802"(identical protein binding)|go:"GO:0043005"(neuron projection)|go:"GO:0043488"(regulation of mRNA stability)|go:"GO:0045109"(intermediate filament organization)|go:"GO:0045111"(intermediate filament cytoskeleton)|go:"GO:0045335"(phagocytic vesicle)|go:"GO:0045727"(positive regulation of translation)|go:"GO:0060020"(Bergmann glial cell differentiation)|go:"GO:0070307"(lens fiber cell development)|go:"GO:0060395"(SMAD protein signal transduction)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071222"(cellular response to lipopolysaccharide)|go:"GO:0071225"(cellular response to muramyl dipeptide)|go:"GO:0071346"(cellular response to interferon-gamma)|go:"GO:0097110"(scaffold protein binding)|go:"GO:1990254"(keratin filament binding)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR006821(Intermediate filament, DNA-binding region)|interpro:IPR018039|interpro:IPR027699|interpro:IPR039008|mint:P08670|rcsb pdb:1GK4|rcsb pdb:1GK6|rcsb pdb:1GK7|rcsb pdb:3G1E|rcsb pdb:3KLT|rcsb pdb:3S4R|rcsb pdb:3SSU|rcsb pdb:3SWK|rcsb pdb:3TRT|rcsb pdb:3UF1|rcsb pdb:4MCY|rcsb pdb:4MCZ|rcsb pdb:4MD0|rcsb pdb:4MD5|rcsb pdb:4MDI|rcsb pdb:4MDJ|rcsb pdb:4YPC|rcsb pdb:4YV3|rcsb pdb:5WHF|rcsb pdb:6ATF|rcsb pdb:6ATI|rcsb pdb:6BIR|rcsb pdb:6YXK|reactome:R-HSA-264870|reactome:R-HSA-390522|reactome:R-HSA-6785807|reactome:R-HSA-9013422|reactome:R-HSA-9613829|reactome:R-HSA-9615710|reactome:R-HSA-9646399|refseq:XP_006717563.1|dip:DIP-32507N - - - figure legend:Fig. 5A, Supp. Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells) - 2020/05/21 2021/04/12 rogid:WEdwMYKpu1uQll5NXnMm4P51R4E9606 rogid:GhAhVuXMNxi6P5J0CfNi5l9bjRk9606 rigid:1P63pNv1yn3F27gcT2OsGH/3EDQ false green fluorescent protein tag:n-n|mutation disrupting interaction strength:406-406,404-404 - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q8NHP6 uniprotkb:E9PDF6 intact:EBI-2812848|uniprotkb:Q8NA83|uniprotkb:Q8N3H2|ensembl:ENSP00000369860 intact:EBI-25617580|ensembl:ENSP00000376130 psi-mi:mspd2_human(display_long)|uniprotkb:MOSPD2(gene name)|psi-mi:MOSPD2(display_short) psi-mi:e9pdf6_human(display_long)|uniprotkb:MYO1B(gene name)|psi-mi:MYO1B(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Di et al. (2018) pubmed:29858488|imex:IM-28178 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-25617558|imex:IM-28178-11 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001170946.1|refseq:NP_689794.1|go:"GO:0090023"(positive regulation of neutrophil chemotaxis)|go:"GO:0090026"(positive regulation of monocyte chemotaxis)|go:"GO:0140284"(endoplasmic reticulum-endosome membrane contact site)|interpro:IPR000535(Major sperm protein)|interpro:IPR001251(Cellular retinaldehyde-binding/triple function, C-terminal)|interpro:IPR008962(PapD-like)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR036273|interpro:IPR036865|mint:Q8NHP6|rcsb pdb:6TQS|rcsb pdb:6TQT|rcsb pdb:6TQU|reactome:R-HSA-6798695|reactome:R-HSA-9013405|ensembl:ENSG00000130150(gene)|ensembl:ENST00000380492(transcript)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006935"(chemotaxis)|go:"GO:0016020"(membrane)|go:"GO:0035579"(specific granule membrane)|go:"GO:0044232"(organelle membrane contact site) go:"GO:0003774"(cytoskeletal motor activity)|go:"GO:0003779"(actin binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005886"(plasma membrane)|go:"GO:0016459"(myosin complex)|interpro:IPR000048(IQ calmodulin-binding region)|interpro:IPR001609(Myosin head, motor region)|interpro:IPR010926(Myosin tail 2)|interpro:IPR027417|interpro:IPR036072|interpro:IPR036961|ensembl:ENSG00000128641(gene)|ensembl:ENST00000392316(transcript)|refseq:NP_001317166.1 - - - figure legend:Fig. 5A, Supp. Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells) - 2020/05/21 2021/04/12 rogid:WEdwMYKpu1uQll5NXnMm4P51R4E9606 rogid:9JCFYwbtYfIBwmEYVxkysQQZJ1E9606 rigid:1P63pNv1yn3F27gcT2OsGH/3EDQ false green fluorescent protein tag:n-n|mutation disrupting interaction strength:406-406,404-404 - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q8NHP6 uniprotkb:F8WJN3 intact:EBI-2812848|uniprotkb:Q8NA83|uniprotkb:Q8N3H2|ensembl:ENSP00000369860 intact:EBI-25617564|ensembl:ENSP00000391437 psi-mi:mspd2_human(display_long)|uniprotkb:MOSPD2(gene name)|psi-mi:MOSPD2(display_short) psi-mi:f8wjn3_human(display_long)|uniprotkb:CPSF6(gene name)|psi-mi:CPSF6(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Di et al. (2018) pubmed:29858488|imex:IM-28178 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-25617558|imex:IM-28178-11 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001170946.1|refseq:NP_689794.1|go:"GO:0090023"(positive regulation of neutrophil chemotaxis)|go:"GO:0090026"(positive regulation of monocyte chemotaxis)|go:"GO:0140284"(endoplasmic reticulum-endosome membrane contact site)|interpro:IPR000535(Major sperm protein)|interpro:IPR001251(Cellular retinaldehyde-binding/triple function, C-terminal)|interpro:IPR008962(PapD-like)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR036273|interpro:IPR036865|mint:Q8NHP6|rcsb pdb:6TQS|rcsb pdb:6TQT|rcsb pdb:6TQU|reactome:R-HSA-6798695|reactome:R-HSA-9013405|ensembl:ENSG00000130150(gene)|ensembl:ENST00000380492(transcript)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006935"(chemotaxis)|go:"GO:0016020"(membrane)|go:"GO:0035579"(specific granule membrane)|go:"GO:0044232"(organelle membrane contact site) ensembl:ENSG00000111605(gene)|ensembl:ENST00000456847(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005849"(mRNA cleavage factor complex)|go:"GO:0016607"(nuclear speck)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR034769|interpro:IPR034772|interpro:IPR035979 - - - figure legend:Fig. 5A, Supp. Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells) - 2020/05/21 2021/04/12 rogid:WEdwMYKpu1uQll5NXnMm4P51R4E9606 rogid:2OIknBbdm7f+AQGpcYzRFoHSBbg9606 rigid:1P63pNv1yn3F27gcT2OsGH/3EDQ false green fluorescent protein tag:n-n|mutation disrupting interaction strength:406-406,404-404 - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q8NHP6 uniprotkb:Q96TC7 intact:EBI-2812848|uniprotkb:Q8NA83|uniprotkb:Q8N3H2|ensembl:ENSP00000369860 intact:EBI-1056589|uniprotkb:A9UMZ9|uniprotkb:Q6ZWE9|uniprotkb:Q96H23|uniprotkb:Q96SD6|uniprotkb:Q9H6G1|uniprotkb:Q9NVQ6|uniprotkb:B3KRR3|intact:EBI-2563869|ensembl:ENSP00000260385|ensembl:ENSP00000342493 psi-mi:mspd2_human(display_long)|uniprotkb:MOSPD2(gene name)|psi-mi:MOSPD2(display_short) psi-mi:rmd3_human(display_long)|uniprotkb:Protein tyrosine phosphatase-interacting protein 51(gene name synonym)|uniprotkb:TCPTP-interacting protein 51(gene name synonym)|uniprotkb:UNQ3122/PRO10274(orf name)|uniprotkb:hucep-10(orf name)|uniprotkb:RMDN3(gene name)|psi-mi:RMDN3(display_short)|uniprotkb:Cerebral protein 10(gene name synonym)|uniprotkb:FAM82A2(gene name synonym)|uniprotkb:FAM82C(gene name synonym)|uniprotkb:PTPIP51(gene name synonym)|uniprotkb:Protein FAM82A2(gene name synonym)|uniprotkb:Protein FAM82C(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Di et al. (2018) pubmed:29858488|imex:IM-28178 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-25617558|imex:IM-28178-11 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001170946.1|refseq:NP_689794.1|go:"GO:0090023"(positive regulation of neutrophil chemotaxis)|go:"GO:0090026"(positive regulation of monocyte chemotaxis)|go:"GO:0140284"(endoplasmic reticulum-endosome membrane contact site)|interpro:IPR000535(Major sperm protein)|interpro:IPR001251(Cellular retinaldehyde-binding/triple function, C-terminal)|interpro:IPR008962(PapD-like)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR036273|interpro:IPR036865|mint:Q8NHP6|rcsb pdb:6TQS|rcsb pdb:6TQT|rcsb pdb:6TQU|reactome:R-HSA-6798695|reactome:R-HSA-9013405|ensembl:ENSG00000130150(gene)|ensembl:ENST00000380492(transcript)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006935"(chemotaxis)|go:"GO:0016020"(membrane)|go:"GO:0035579"(specific granule membrane)|go:"GO:0044232"(organelle membrane contact site) refseq:NP_060615.1|refseq:NP_001310823.1|refseq:NP_001310824.1|refseq:NP_001291731.1|ensembl:ENSG00000137824(gene)|ensembl:ENST00000260385(transcript)|ensembl:ENST00000338376(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005876"(spindle microtubule)|go:"GO:0006874"(cellular calcium ion homeostasis)|go:"GO:0006915"(apoptotic process)|go:"GO:0008017"(microtubule binding)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030154"(cell differentiation)|go:"GO:0044232"(organelle membrane contact site)|go:"GO:0045171"(intercellular bridge)|go:"GO:0097431"(mitotic spindle pole)|interpro:IPR011990(Tetratricopeptide-like helical)|rcsb pdb:7CC7 - - - figure legend:Fig. 5A, Supp. Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells) - 2020/05/21 2021/04/12 rogid:WEdwMYKpu1uQll5NXnMm4P51R4E9606 rogid:+y9NPJiIL0BOpjWINH8zcfp5b9o9606 rigid:1P63pNv1yn3F27gcT2OsGH/3EDQ false green fluorescent protein tag:n-n|mutation disrupting interaction strength:406-406,404-404 - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q8NHP6 uniprotkb:P16989 intact:EBI-2812848|uniprotkb:Q8NA83|uniprotkb:Q8N3H2|ensembl:ENSP00000369860 intact:EBI-358193|uniprotkb:Q14121|uniprotkb:Q969N6|uniprotkb:Q96B76|uniprotkb:B2RBW6|intact:EBI-2560381|ensembl:ENSP00000228251 psi-mi:mspd2_human(display_long)|uniprotkb:MOSPD2(gene name)|psi-mi:MOSPD2(display_short) psi-mi:ybox3_human(display_long)|uniprotkb:YBX3(gene name)|psi-mi:YBX3(display_short)|uniprotkb:CSDA(gene name synonym)|uniprotkb:Cold shock domain-containing protein A(gene name synonym)|uniprotkb:DBPA(gene name synonym)|uniprotkb:DNA-binding protein A(gene name synonym)|uniprotkb:Single-strand DNA-binding protein NF-GMB(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Di et al. (2018) pubmed:29858488|imex:IM-28178 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-25617558|imex:IM-28178-11 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001170946.1|refseq:NP_689794.1|go:"GO:0090023"(positive regulation of neutrophil chemotaxis)|go:"GO:0090026"(positive regulation of monocyte chemotaxis)|go:"GO:0140284"(endoplasmic reticulum-endosome membrane contact site)|interpro:IPR000535(Major sperm protein)|interpro:IPR001251(Cellular retinaldehyde-binding/triple function, C-terminal)|interpro:IPR008962(PapD-like)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR036273|interpro:IPR036865|mint:Q8NHP6|rcsb pdb:6TQS|rcsb pdb:6TQT|rcsb pdb:6TQU|reactome:R-HSA-6798695|reactome:R-HSA-9013405|ensembl:ENSG00000130150(gene)|ensembl:ENST00000380492(transcript)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006935"(chemotaxis)|go:"GO:0016020"(membrane)|go:"GO:0035579"(specific granule membrane)|go:"GO:0044232"(organelle membrane contact site) go:"GO:0046622"(positive regulation of organ growth)|refseq:NP_001138898.1|refseq:NP_003642.3|dip:DIP-42489N|ensembl:ENSG00000060138(gene)|ensembl:ENST00000228251(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0003676"(nucleic acid binding)|go:"GO:0003723"(RNA binding)|go:"GO:0003730"(mRNA 3'-UTR binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005923"(bicellular tight junction)|go:"GO:0007283"(spermatogenesis)|go:"GO:0008584"(male gonad development)|go:"GO:0009566"(fertilization)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0031267"(small GTPase binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0048642"(negative regulation of skeletal muscle tissue development)|go:"GO:0060546"(negative regulation of necroptotic process)|go:"GO:0070935"(3'-UTR-mediated mRNA stabilization)|go:"GO:0071356"(cellular response to tumor necrosis factor)|go:"GO:0071474"(cellular hyperosmotic response)|go:"GO:1902219"(negative regulation of intrinsic apoptotic signaling pathway in response to osmotic stress)|go:"GO:1905538"(polysome binding)|go:"GO:2000767"(positive regulation of cytoplasmic translation)|interpro:IPR002059(Cold-shock protein, DNA-binding)|interpro:IPR011129(Cold shock protein)|interpro:IPR012340(Nucleic acid-binding, OB-fold)|interpro:IPR019844|mint:P16989 - - - figure legend:Fig. 5A, Supp. Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells) - 2020/05/21 2021/04/12 rogid:WEdwMYKpu1uQll5NXnMm4P51R4E9606 rogid:cWuhmwOBWe5HdgPG1gyN7KzN4Rs9606 rigid:1P63pNv1yn3F27gcT2OsGH/3EDQ false green fluorescent protein tag:n-n|mutation disrupting interaction strength:406-406,404-404 - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q8NHP6 uniprotkb:P52597 intact:EBI-2812848|uniprotkb:Q8NA83|uniprotkb:Q8N3H2|ensembl:ENSP00000369860 intact:EBI-352986|ensembl:ENSP00000338477|ensembl:ENSP00000349573|ensembl:ENSP00000400433|ensembl:ENSP00000438061|ensembl:ENSP00000507787|ensembl:ENSP00000348345|uniprotkb:Q5T0N2|uniprotkb:Q96AU2|uniprotkb:B3KM84 psi-mi:mspd2_human(display_long)|uniprotkb:MOSPD2(gene name)|psi-mi:MOSPD2(display_short) psi-mi:hnrpf_human(display_long)|uniprotkb:HNRNPF(gene name)|psi-mi:HNRNPF(display_short)|uniprotkb:HNRPF(gene name synonym)|uniprotkb:Nucleolin-like protein mcs94-1(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Di et al. (2018) pubmed:29858488|imex:IM-28178 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-25617558|imex:IM-28178-11 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001170946.1|refseq:NP_689794.1|go:"GO:0090023"(positive regulation of neutrophil chemotaxis)|go:"GO:0090026"(positive regulation of monocyte chemotaxis)|go:"GO:0140284"(endoplasmic reticulum-endosome membrane contact site)|interpro:IPR000535(Major sperm protein)|interpro:IPR001251(Cellular retinaldehyde-binding/triple function, C-terminal)|interpro:IPR008962(PapD-like)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR036273|interpro:IPR036865|mint:Q8NHP6|rcsb pdb:6TQS|rcsb pdb:6TQT|rcsb pdb:6TQU|reactome:R-HSA-6798695|reactome:R-HSA-9013405|ensembl:ENSG00000130150(gene)|ensembl:ENST00000380492(transcript)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006935"(chemotaxis)|go:"GO:0016020"(membrane)|go:"GO:0035579"(specific granule membrane)|go:"GO:0044232"(organelle membrane contact site) interpro:IPR012996(Zinc finger, CHHC-type)|interpro:IPR035979|mint:P52597|rcsb pdb:2HGL|rcsb pdb:2HGM|rcsb pdb:2HGN|rcsb pdb:2KFY|rcsb pdb:2KG0|rcsb pdb:2KG1|rcsb pdb:3TFY|reactome:R-HSA-6803529|reactome:R-HSA-72163|reactome:R-HSA-72203|reactome:R-HSA-8950505|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|ensembl:ENSG00000169813(gene)|ensembl:ENST00000337970(transcript)|ensembl:ENST00000356053(transcript)|ensembl:ENST00000357065(transcript)|ensembl:ENST00000443950(transcript)|ensembl:ENST00000544000(transcript)|ensembl:ENST00000682386(transcript)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0003723"(RNA binding)|go:"GO:0003727"(single-stranded RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006396"(RNA processing)|go:"GO:0016020"(membrane)|go:"GO:0043484"(regulation of RNA splicing)|go:"GO:0071013"(catalytic step 2 spliceosome)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR000504(RNA recognition motif, RNP-1)|refseq:NP_001091674.1|refseq:NP_001091675.1|refseq:NP_001091676.1|refseq:NP_001091677.1|refseq:NP_001091678.1|refseq:NP_004957.1|dip:DIP-33145N - - - figure legend:Fig. 5A, Supp. Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells) - 2020/05/21 2021/04/12 rogid:WEdwMYKpu1uQll5NXnMm4P51R4E9606 rogid:pblzpldZOa5vlZ+zGQY9qyWCxaw9606 rigid:1P63pNv1yn3F27gcT2OsGH/3EDQ false green fluorescent protein tag:n-n|mutation disrupting interaction strength:406-406,404-404 - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q8NHP6 uniprotkb:Q96R06 intact:EBI-2812848|uniprotkb:Q8NA83|uniprotkb:Q8N3H2|ensembl:ENSP00000369860 intact:EBI-413317|uniprotkb:O95213|uniprotkb:Q9BWE8|uniprotkb:Q9NT17|uniprotkb:Q9UFE6|intact:EBI-28972684|ensembl:ENSP00000323300 psi-mi:mspd2_human(display_long)|uniprotkb:MOSPD2(gene name)|psi-mi:MOSPD2(display_short) psi-mi:spag5_human(display_long)|uniprotkb:SPAG5(gene name)|psi-mi:SPAG5(display_short)|uniprotkb:Astrin(gene name synonym)|uniprotkb:Mitotic spindle-associated protein p126(gene name synonym)|uniprotkb:Deepest(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Di et al. (2018) pubmed:29858488|imex:IM-28178 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-25617558|imex:IM-28178-11 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001170946.1|refseq:NP_689794.1|go:"GO:0090023"(positive regulation of neutrophil chemotaxis)|go:"GO:0090026"(positive regulation of monocyte chemotaxis)|go:"GO:0140284"(endoplasmic reticulum-endosome membrane contact site)|interpro:IPR000535(Major sperm protein)|interpro:IPR001251(Cellular retinaldehyde-binding/triple function, C-terminal)|interpro:IPR008962(PapD-like)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR036273|interpro:IPR036865|mint:Q8NHP6|rcsb pdb:6TQS|rcsb pdb:6TQT|rcsb pdb:6TQU|reactome:R-HSA-6798695|reactome:R-HSA-9013405|ensembl:ENSG00000130150(gene)|ensembl:ENST00000380492(transcript)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006935"(chemotaxis)|go:"GO:0016020"(membrane)|go:"GO:0035579"(specific granule membrane)|go:"GO:0044232"(organelle membrane contact site) refseq:NP_006452.3|ensembl:ENSP00000323300|ensembl:ENSG00000076382(gene)|ensembl:ENST00000321765(transcript)|go:"GO:0000070"(mitotic sister chromatid segregation)|go:"GO:0000776"(kinetochore)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0007051"(spindle organization)|go:"GO:0007059"(chromosome segregation)|go:"GO:0008017"(microtubule binding)|go:"GO:0016604"(nuclear body)|go:"GO:0030496"(midbody)|go:"GO:0032388"(positive regulation of intracellular transport)|go:"GO:0034451"(centriolar satellite)|go:"GO:0035253"(ciliary rootlet)|go:"GO:0035371"(microtubule plus-end)|go:"GO:0036064"(ciliary basal body)|go:"GO:0051294"(establishment of spindle orientation)|go:"GO:0051301"(cell division)|go:"GO:0051988"(regulation of attachment of spindle microtubules to kinetochore)|go:"GO:0071539"(protein localization to centrosome)|go:"GO:0072686"(mitotic spindle)|go:"GO:0090235"(regulation of metaphase plate congression)|go:"GO:0097431"(mitotic spindle pole)|go:"GO:1905832"(positive regulation of spindle assembly)|interpro:IPR028728|mint:Q96R06|dip:DIP-30998N - - - figure legend:Fig. 5A, Supp. Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells) - 2020/05/21 2021/04/12 rogid:WEdwMYKpu1uQll5NXnMm4P51R4E9606 rogid:WOMksaINKpqSxqeGIzbmcSRcgdw9606 rigid:1P63pNv1yn3F27gcT2OsGH/3EDQ false green fluorescent protein tag:n-n|mutation disrupting interaction strength:406-406,404-404 - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q8NHP6 uniprotkb:Q8TD16 intact:EBI-2812848|uniprotkb:Q8NA83|uniprotkb:Q8N3H2|ensembl:ENSP00000369860 intact:EBI-2372628|uniprotkb:O75181|uniprotkb:Q5TBQ2|uniprotkb:Q5TBQ3|uniprotkb:Q96LH2|uniprotkb:Q9BT84|uniprotkb:Q9H561|ensembl:ENSP00000364662 psi-mi:mspd2_human(display_long)|uniprotkb:MOSPD2(gene name)|psi-mi:MOSPD2(display_short) psi-mi:bicd2_human(display_long)|uniprotkb:BICD2(gene name)|psi-mi:BICD2(display_short)|uniprotkb:KIAA0699(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Di et al. (2018) pubmed:29858488|imex:IM-28178 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-25617558|imex:IM-28178-11 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001170946.1|refseq:NP_689794.1|go:"GO:0090023"(positive regulation of neutrophil chemotaxis)|go:"GO:0090026"(positive regulation of monocyte chemotaxis)|go:"GO:0140284"(endoplasmic reticulum-endosome membrane contact site)|interpro:IPR000535(Major sperm protein)|interpro:IPR001251(Cellular retinaldehyde-binding/triple function, C-terminal)|interpro:IPR008962(PapD-like)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR036273|interpro:IPR036865|mint:Q8NHP6|rcsb pdb:6TQS|rcsb pdb:6TQT|rcsb pdb:6TQU|reactome:R-HSA-6798695|reactome:R-HSA-9013405|ensembl:ENSG00000130150(gene)|ensembl:ENST00000380492(transcript)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006935"(chemotaxis)|go:"GO:0016020"(membrane)|go:"GO:0035579"(specific granule membrane)|go:"GO:0044232"(organelle membrane contact site) refseq:NP_001003800.1|refseq:NP_056065.1|dip:DIP-53426N|ensembl:ENSG00000185963(gene)|ensembl:ENST00000375512(transcript)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005642"(annulate lamellae)|go:"GO:0005643"(nuclear pore)|go:"GO:0005737"(cytoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006890"(retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum)|go:"GO:0007018"(microtubule-based movement)|go:"GO:0008093"(cytoskeletal anchor activity)|go:"GO:0015031"(protein transport)|go:"GO:0031267"(small GTPase binding)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0033365"(protein localization to organelle)|go:"GO:0034067"(protein localization to Golgi apparatus)|go:"GO:0034452"(dynactin binding)|go:"GO:0051028"(mRNA transport)|go:"GO:0051642"(centrosome localization)|go:"GO:0051959"(dynein light intermediate chain binding)|go:"GO:0070507"(regulation of microtubule cytoskeleton organization)|go:"GO:0070840"(dynein complex binding)|go:"GO:0072385"(minus-end-directed organelle transport along microtubule)|go:"GO:0072393"(microtubule anchoring at microtubule organizing center)|interpro:IPR018477|rcsb pdb:6OFP|rcsb pdb:6PSE|reactome:R-HSA-6811436 - - - figure legend:Fig. 5A, Supp. Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells) - 2020/05/21 2021/04/12 rogid:WEdwMYKpu1uQll5NXnMm4P51R4E9606 rogid:6MPNarWaiURuFhlX154W5E/1kpM9606 rigid:1P63pNv1yn3F27gcT2OsGH/3EDQ false green fluorescent protein tag:n-n|mutation disrupting interaction strength:406-406,404-404 - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q8NHP6 uniprotkb:Q9UHW5 intact:EBI-2812848|uniprotkb:Q8NA83|uniprotkb:Q8N3H2|ensembl:ENSP00000369860 intact:EBI-395491|uniprotkb:Q53FS3|uniprotkb:Q6UVZ6|uniprotkb:Q7Z3D3|uniprotkb:Q8NEI2|uniprotkb:Q96HK9|uniprotkb:B2RC54|uniprotkb:D4YWV1|ensembl:ENSP00000228827|uniprotkb:F5H759 psi-mi:mspd2_human(display_long)|uniprotkb:MOSPD2(gene name)|psi-mi:MOSPD2(display_short) psi-mi:gpn3_human(display_long)|uniprotkb:ATPBD1C(gene name synonym)|uniprotkb:ATP-binding domain 1 family member C(gene name synonym)|uniprotkb:GPN3(gene name)|psi-mi:GPN3(display_short)|uniprotkb:AD-009(orf name)|uniprotkb:UNQ1876/PRO4319(orf name) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Di et al. (2018) pubmed:29858488|imex:IM-28178 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-25617558|imex:IM-28178-11 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001170946.1|refseq:NP_689794.1|go:"GO:0090023"(positive regulation of neutrophil chemotaxis)|go:"GO:0090026"(positive regulation of monocyte chemotaxis)|go:"GO:0140284"(endoplasmic reticulum-endosome membrane contact site)|interpro:IPR000535(Major sperm protein)|interpro:IPR001251(Cellular retinaldehyde-binding/triple function, C-terminal)|interpro:IPR008962(PapD-like)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR036273|interpro:IPR036865|mint:Q8NHP6|rcsb pdb:6TQS|rcsb pdb:6TQT|rcsb pdb:6TQU|reactome:R-HSA-6798695|reactome:R-HSA-9013405|ensembl:ENSG00000130150(gene)|ensembl:ENST00000380492(transcript)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006935"(chemotaxis)|go:"GO:0016020"(membrane)|go:"GO:0035579"(specific granule membrane)|go:"GO:0044232"(organelle membrane contact site) refseq:NP_001157844.1|refseq:NP_001157845.1|refseq:NP_057385.3|ensembl:ENSG00000111231(gene)|ensembl:ENST00000228827(transcript)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0032991"(protein-containing complex)|interpro:IPR004130(Protein of unknown function, ATP binding)|interpro:IPR027417|interpro:IPR030228|mint:Q9UHW5 - - - figure legend:Fig. 5A, Supp. Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells) - 2020/05/21 2021/04/12 rogid:WEdwMYKpu1uQll5NXnMm4P51R4E9606 rogid:fKBsnLcvitaM76zQUW+MQXDPxTA9606 rigid:1P63pNv1yn3F27gcT2OsGH/3EDQ false green fluorescent protein tag:n-n|mutation disrupting interaction strength:406-406,404-404 - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q8NHP6 uniprotkb:Q96A33 intact:EBI-2812848|uniprotkb:Q8NA83|uniprotkb:Q8N3H2|ensembl:ENSP00000369860 intact:EBI-720151|uniprotkb:Q96D00|uniprotkb:Q96JZ7|uniprotkb:Q9H3E4|uniprotkb:Q9NRG3|uniprotkb:B2RAS8|uniprotkb:D3DU20|ensembl:ENSP00000225726|ensembl:ENSP00000384888 psi-mi:mspd2_human(display_long)|uniprotkb:MOSPD2(gene name)|psi-mi:MOSPD2(display_short) psi-mi:ccd47_human(display_long)|uniprotkb:CCDC47(gene name)|psi-mi:CCDC47(display_short)|uniprotkb:Calumin(gene name synonym)|uniprotkb:Coiled-coil domain-containing protein 47(gene name synonym)|uniprotkb:GK001(orf name)|uniprotkb:MSTP041(orf name)|uniprotkb:PSEC0077(orf name) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Di et al. (2018) pubmed:29858488|imex:IM-28178 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-25617558|imex:IM-28178-11 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001170946.1|refseq:NP_689794.1|go:"GO:0090023"(positive regulation of neutrophil chemotaxis)|go:"GO:0090026"(positive regulation of monocyte chemotaxis)|go:"GO:0140284"(endoplasmic reticulum-endosome membrane contact site)|interpro:IPR000535(Major sperm protein)|interpro:IPR001251(Cellular retinaldehyde-binding/triple function, C-terminal)|interpro:IPR008962(PapD-like)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR036273|interpro:IPR036865|mint:Q8NHP6|rcsb pdb:6TQS|rcsb pdb:6TQT|rcsb pdb:6TQU|reactome:R-HSA-6798695|reactome:R-HSA-9013405|ensembl:ENSG00000130150(gene)|ensembl:ENST00000380492(transcript)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006935"(chemotaxis)|go:"GO:0016020"(membrane)|go:"GO:0035579"(specific granule membrane)|go:"GO:0044232"(organelle membrane contact site) refseq:NP_064583.2|ensembl:ENSG00000108588(gene)|ensembl:ENST00000225726(transcript)|ensembl:ENST00000403162(transcript)|go:"GO:0001649"(osteoblast differentiation)|go:"GO:0003723"(RNA binding)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0006983"(ER overload response)|go:"GO:0009791"(post-embryonic development)|go:"GO:0016020"(membrane)|go:"GO:0030176"(integral component of endoplasmic reticulum membrane)|go:"GO:0030433"(ubiquitin-dependent ERAD pathway)|go:"GO:0032469"(endoplasmic reticulum calcium ion homeostasis)|go:"GO:0036503"(ERAD pathway)|go:"GO:0043022"(ribosome binding)|go:"GO:0044183"(protein folding chaperone)|go:"GO:0045048"(protein insertion into ER membrane)|interpro:IPR012879(Protein of unknown function DUF1682)|mint:Q96A33|rcsb pdb:6W6L|go:"GO:0030867"(rough endoplasmic reticulum membrane)|refseq:XP_005257584.1 - - - figure legend:Fig. 5A, Supp. Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells) - 2020/05/21 2021/04/12 rogid:WEdwMYKpu1uQll5NXnMm4P51R4E9606 rogid:DdZFzZrrc4culfYoex0Czf/X6SQ9606 rigid:1P63pNv1yn3F27gcT2OsGH/3EDQ false green fluorescent protein tag:n-n|mutation disrupting interaction strength:406-406,404-404 - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q8NHP6 uniprotkb:P42166 intact:EBI-2812848|uniprotkb:Q8NA83|uniprotkb:Q8N3H2|ensembl:ENSP00000369860 intact:EBI-395393|uniprotkb:P08918|uniprotkb:P08919|uniprotkb:Q14860|uniprotkb:Q16295|ensembl:ENSP00000266732 psi-mi:mspd2_human(display_long)|uniprotkb:MOSPD2(gene name)|psi-mi:MOSPD2(display_short) psi-mi:lap2a_human(display_long)|uniprotkb:TMPO(gene name)|psi-mi:TMPO(display_short)|uniprotkb:LAP2(gene name synonym)|uniprotkb:Thymopoietin isoform alpha(gene name synonym)|uniprotkb:Thymopoietin-related peptide isoform alpha(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Di et al. (2018) pubmed:29858488|imex:IM-28178 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-25617558|imex:IM-28178-11 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001170946.1|refseq:NP_689794.1|go:"GO:0090023"(positive regulation of neutrophil chemotaxis)|go:"GO:0090026"(positive regulation of monocyte chemotaxis)|go:"GO:0140284"(endoplasmic reticulum-endosome membrane contact site)|interpro:IPR000535(Major sperm protein)|interpro:IPR001251(Cellular retinaldehyde-binding/triple function, C-terminal)|interpro:IPR008962(PapD-like)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR036273|interpro:IPR036865|mint:Q8NHP6|rcsb pdb:6TQS|rcsb pdb:6TQT|rcsb pdb:6TQU|reactome:R-HSA-6798695|reactome:R-HSA-9013405|ensembl:ENSG00000130150(gene)|ensembl:ENST00000380492(transcript)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006935"(chemotaxis)|go:"GO:0016020"(membrane)|go:"GO:0035579"(specific granule membrane)|go:"GO:0044232"(organelle membrane contact site) refseq:NP_003267.1|ensembl:ENSG00000120802(gene)|ensembl:ENST00000266732(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0003677"(DNA binding)|go:"GO:0005521"(lamin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005635"(nuclear envelope)|go:"GO:0045296"(cadherin binding)|interpro:IPR003887(Lamino-associated polypeptide 2/emerin)|interpro:IPR011015(LEM-like fold)|interpro:IPR013146(Thymopoietin LEM)|interpro:IPR021623|mint:P42166|rcsb pdb:1GJJ|rcsb pdb:1H9E|rcsb pdb:1H9F - - - figure legend:Fig. 5A, Supp. Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells) - 2020/05/21 2021/04/12 rogid:WEdwMYKpu1uQll5NXnMm4P51R4E9606 rogid:/kq+6sQN9B8jf+Ee4uPj7gtWe509606 rigid:1P63pNv1yn3F27gcT2OsGH/3EDQ false green fluorescent protein tag:n-n|mutation disrupting interaction strength:406-406,404-404 - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q8NHP6 uniprotkb:Q14764 intact:EBI-2812848|uniprotkb:Q8NA83|uniprotkb:Q8N3H2|ensembl:ENSP00000369860 intact:EBI-2816254|uniprotkb:Q9BPW6|uniprotkb:Q9BQT1|uniprotkb:Q96BG4|uniprotkb:Q9UBD1|intact:EBI-28971732|ensembl:ENSP00000349977|ensembl:ENSP00000378760 psi-mi:mspd2_human(display_long)|uniprotkb:MOSPD2(gene name)|psi-mi:MOSPD2(display_short) psi-mi:mvp_human(display_long)|uniprotkb:MVP(gene name)|psi-mi:MVP(display_short)|uniprotkb:LRP(gene name synonym)|uniprotkb:Lung resistance-related protein(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Di et al. (2018) pubmed:29858488|imex:IM-28178 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-25617558|imex:IM-28178-11 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001170946.1|refseq:NP_689794.1|go:"GO:0090023"(positive regulation of neutrophil chemotaxis)|go:"GO:0090026"(positive regulation of monocyte chemotaxis)|go:"GO:0140284"(endoplasmic reticulum-endosome membrane contact site)|interpro:IPR000535(Major sperm protein)|interpro:IPR001251(Cellular retinaldehyde-binding/triple function, C-terminal)|interpro:IPR008962(PapD-like)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR036273|interpro:IPR036865|mint:Q8NHP6|rcsb pdb:6TQS|rcsb pdb:6TQT|rcsb pdb:6TQU|reactome:R-HSA-6798695|reactome:R-HSA-9013405|ensembl:ENSG00000130150(gene)|ensembl:ENST00000380492(transcript)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006935"(chemotaxis)|go:"GO:0016020"(membrane)|go:"GO:0035579"(specific granule membrane)|go:"GO:0044232"(organelle membrane contact site) ensembl:ENSP00000349977|ensembl:ENSP00000378760|refseq:NP_001280133.1|refseq:NP_001280134.1|refseq:NP_005106.2|refseq:NP_059447.2|ensembl:ENSG00000013364(gene)|ensembl:ENST00000357402(transcript)|ensembl:ENST00000395353(transcript)|go:"GO:0005576"(extracellular region)|go:"GO:0005634"(nucleus)|go:"GO:0005643"(nuclear pore)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0015031"(protein transport)|go:"GO:0016020"(membrane)|go:"GO:0019901"(protein kinase binding)|go:"GO:0019903"(protein phosphatase binding)|go:"GO:0031953"(negative regulation of protein autophosphorylation)|go:"GO:0034774"(secretory granule lumen)|go:"GO:0038127"(ERBB signaling pathway)|go:"GO:0042059"(negative regulation of epidermal growth factor receptor signaling pathway)|go:"GO:0042802"(identical protein binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051028"(mRNA transport)|go:"GO:0061099"(negative regulation of protein tyrosine kinase activity)|go:"GO:0070062"(extracellular exosome)|go:"GO:1904813"(ficolin-1-rich granule lumen)|interpro:IPR002499(Major vault protein, N-terminal)|interpro:IPR021870|interpro:IPR036013|interpro:IPR039059|interpro:IPR040989|interpro:IPR041134|interpro:IPR041136|interpro:IPR041139|interpro:IPR043023|interpro:IPR043179|mint:Q14764|rcsb pdb:1Y7X|reactome:R-HSA-6798695 - - - figure legend:Fig. 5A, Supp. Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells) - 2020/05/21 2021/04/12 rogid:WEdwMYKpu1uQll5NXnMm4P51R4E9606 rogid:z/Hc6TeTzO5QSpZ8AUXiI2ox4eg9606 rigid:1P63pNv1yn3F27gcT2OsGH/3EDQ false green fluorescent protein tag:n-n|mutation disrupting interaction strength:406-406,404-404 - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q8NHP6 uniprotkb:Q13509 intact:EBI-2812848|uniprotkb:Q8NA83|uniprotkb:Q8N3H2|ensembl:ENSP00000369860 intact:EBI-350989|uniprotkb:Q9BTZ0|uniprotkb:Q9BW10|ensembl:ENSP00000320295|uniprotkb:A8K854 psi-mi:mspd2_human(display_long)|uniprotkb:MOSPD2(gene name)|psi-mi:MOSPD2(display_short) psi-mi:tbb3_human(display_long)|uniprotkb:TUBB3(gene name)|psi-mi:TUBB3(display_short)|uniprotkb:TUBB4(gene name synonym)|uniprotkb:Tubulin beta-III(gene name synonym)|uniprotkb:Tubulin beta-4 chain(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Di et al. (2018) pubmed:29858488|imex:IM-28178 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-25617558|imex:IM-28178-11 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001170946.1|refseq:NP_689794.1|go:"GO:0090023"(positive regulation of neutrophil chemotaxis)|go:"GO:0090026"(positive regulation of monocyte chemotaxis)|go:"GO:0140284"(endoplasmic reticulum-endosome membrane contact site)|interpro:IPR000535(Major sperm protein)|interpro:IPR001251(Cellular retinaldehyde-binding/triple function, C-terminal)|interpro:IPR008962(PapD-like)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR036273|interpro:IPR036865|mint:Q8NHP6|rcsb pdb:6TQS|rcsb pdb:6TQT|rcsb pdb:6TQU|reactome:R-HSA-6798695|reactome:R-HSA-9013405|ensembl:ENSG00000130150(gene)|ensembl:ENST00000380492(transcript)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006935"(chemotaxis)|go:"GO:0016020"(membrane)|go:"GO:0035579"(specific granule membrane)|go:"GO:0044232"(organelle membrane contact site) refseq:NP_001184110.1|refseq:NP_006077.2|reactome:R-HSA-6811434|reactome:R-HSA-6811436|reactome:R-HSA-68877|reactome:R-HSA-8852276|reactome:R-HSA-8955332|reactome:R-HSA-9609690|reactome:R-HSA-9609736|reactome:R-HSA-9619483|reactome:R-HSA-9646399|reactome:R-HSA-9648025|reactome:R-HSA-9668328|reactome:R-HSA-983189|reactome:R-HSA-6807878|ensembl:ENSG00000258947(gene)|ensembl:ENST00000315491(transcript)|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0005200"(structural constituent of cytoskeleton)|go:"GO:0005525"(GTP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005874"(microtubule)|go:"GO:0007411"(axon guidance)|go:"GO:0030027"(lamellipodium)|go:"GO:0030175"(filopodium)|go:"GO:0030424"(axon)|go:"GO:0030425"(dendrite)|go:"GO:0030426"(growth cone)|go:"GO:0042277"(peptide binding)|go:"GO:0043025"(neuronal cell body)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071944"(cell periphery)|go:"GO:1990791"(dorsal root ganglion development)|go:"GO:1990890"(netrin receptor binding)|interpro:IPR000217(Tubulin)|interpro:IPR002453(Beta tubulin)|interpro:IPR003008(Tubulin/FtsZ, GTPase)|interpro:IPR008280(Tubulin/FtsZ, C-terminal)|interpro:IPR013838(Beta tubulin, autoregulation binding site)|interpro:IPR017975|interpro:IPR018316|interpro:IPR023123|interpro:IPR036525|interpro:IPR037103|mint:Q13509|rcsb pdb:5IJ9|rcsb pdb:5JCO|rcsb pdb:6E7B|rcsb pdb:6S8L|rcsb pdb:6WSL|reactome:R-HSA-1445148|reactome:R-HSA-190840|reactome:R-HSA-190861|reactome:R-HSA-2132295|reactome:R-HSA-2467813|reactome:R-HSA-2500257|reactome:R-HSA-3371497|reactome:R-HSA-380320|reactome:R-HSA-389957|reactome:R-HSA-389960|reactome:R-HSA-389977|reactome:R-HSA-437239|reactome:R-HSA-5610787|reactome:R-HSA-5617833|reactome:R-HSA-5620924|reactome:R-HSA-5626467|reactome:R-HSA-5663220|rcsb pdb:5IJ0|dip:DIP-31505N - - - figure legend:Fig. 5A, Supp. Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells) - 2020/05/21 2021/04/12 rogid:WEdwMYKpu1uQll5NXnMm4P51R4E9606 rogid:A69G+idFQmuzkmCsGyBtGVqglSo9606 rigid:1P63pNv1yn3F27gcT2OsGH/3EDQ false green fluorescent protein tag:n-n|mutation disrupting interaction strength:406-406,404-404 - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q8NHP6 uniprotkb:Q14849 intact:EBI-2812848|uniprotkb:Q8NA83|uniprotkb:Q8N3H2|ensembl:ENSP00000369860 intact:EBI-9819324|uniprotkb:A8MXA4|uniprotkb:B4DUY1|uniprotkb:F5H0G2|uniprotkb:Q53Y53|uniprotkb:Q96HM9|ensembl:ENSP00000337446 psi-mi:mspd2_human(display_long)|uniprotkb:MOSPD2(gene name)|psi-mi:MOSPD2(display_short) psi-mi:star3_human(display_long)|uniprotkb:STARD3(gene name)|psi-mi:STARD3(display_short)|uniprotkb:CAB1(gene name synonym)|uniprotkb:MLN64(gene name synonym)|uniprotkb:Metastatic lymph node gene 64 protein(gene name synonym)|uniprotkb:Protein CAB1(gene name synonym)|uniprotkb:START domain-containing protein 3(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Di et al. (2018) pubmed:29858488|imex:IM-28178 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0486"(UniProt) intact:EBI-25618197|imex:IM-28178-13 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001170946.1|refseq:NP_689794.1|go:"GO:0090023"(positive regulation of neutrophil chemotaxis)|go:"GO:0090026"(positive regulation of monocyte chemotaxis)|go:"GO:0140284"(endoplasmic reticulum-endosome membrane contact site)|interpro:IPR000535(Major sperm protein)|interpro:IPR001251(Cellular retinaldehyde-binding/triple function, C-terminal)|interpro:IPR008962(PapD-like)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR036273|interpro:IPR036865|mint:Q8NHP6|rcsb pdb:6TQS|rcsb pdb:6TQT|rcsb pdb:6TQU|reactome:R-HSA-6798695|reactome:R-HSA-9013405|ensembl:ENSG00000130150(gene)|ensembl:ENST00000380492(transcript)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006935"(chemotaxis)|go:"GO:0016020"(membrane)|go:"GO:0035579"(specific granule membrane)|go:"GO:0044232"(organelle membrane contact site) refseq:NP_001159409.1|refseq:NP_001159410.1|refseq:NP_006795.3|refseq:XP_016879530.1|ensembl:ENSG00000131748(gene)|ensembl:ENST00000336308(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005768"(endosome)|go:"GO:0005829"(cytosol)|go:"GO:0006629"(lipid metabolic process)|go:"GO:0006701"(progesterone biosynthetic process)|go:"GO:0006839"(mitochondrial transport)|go:"GO:0008202"(steroid metabolic process)|go:"GO:0008203"(cholesterol metabolic process)|go:"GO:0015485"(cholesterol binding)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030301"(cholesterol transport)|go:"GO:0031902"(late endosome membrane)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0044232"(organelle membrane contact site)|go:"GO:0099044"(vesicle tethering to endoplasmic reticulum)|go:"GO:0120020"(cholesterol transfer activity)|go:"GO:0140284"(endoplasmic reticulum-endosome membrane contact site)|interpro:IPR000799(Steroidogenic acute regulatory protein)|interpro:IPR002913(Lipid-binding START)|interpro:IPR019498|interpro:IPR023393|interpro:IPR029867|rcsb pdb:1EM2|rcsb pdb:2I92|rcsb pdb:5I9J|rcsb pdb:6TQR|rcsb pdb:6TQU|reactome:R-HSA-196108 go:"GO:0005768"(endosome) - - figure legend:Fig. 5B|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells) - 2020/05/21 2020/05/21 rogid:WEdwMYKpu1uQll5NXnMm4P51R4E9606 rogid:WukBgAECun0AKrfWzBlepgVuZlE9606 rigid:fxnjpASU8QRkHkoYVYWTa804T1U false green fluorescent protein tag:n-n|mutation disrupting interaction strength:404-404,406-406 mutation disrupting interaction strength:207-208|flag tag:?-? - - psi-mi:"MI:0705"(anti tag western blot) psi-mi:"MI:0705"(anti tag western blot) uniprotkb:Q8NHP6 uniprotkb:O95772 intact:EBI-2812848|uniprotkb:Q8NA83|uniprotkb:Q8N3H2|ensembl:ENSP00000369860 intact:EBI-3916943|ensembl:ENSP00000009041|ensembl:ENSP00000379334|uniprotkb:A4D1X0 psi-mi:mspd2_human(display_long)|uniprotkb:MOSPD2(gene name)|psi-mi:MOSPD2(display_short) psi-mi:str3n_human(display_long)|uniprotkb:STARD3NL(gene name)|psi-mi:STARD3NL(display_short)|uniprotkb:MENTHO(gene name synonym)|uniprotkb:MLN64 N-terminal domain homolog(gene name synonym)|uniprotkb:UNQ855/PRO1864(orf name) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Di et al. (2018) pubmed:29858488|imex:IM-28178 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0486"(UniProt) intact:EBI-25618239|imex:IM-28178-29 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001170946.1|refseq:NP_689794.1|go:"GO:0090023"(positive regulation of neutrophil chemotaxis)|go:"GO:0090026"(positive regulation of monocyte chemotaxis)|go:"GO:0140284"(endoplasmic reticulum-endosome membrane contact site)|interpro:IPR000535(Major sperm protein)|interpro:IPR001251(Cellular retinaldehyde-binding/triple function, C-terminal)|interpro:IPR008962(PapD-like)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR036273|interpro:IPR036865|mint:Q8NHP6|rcsb pdb:6TQS|rcsb pdb:6TQT|rcsb pdb:6TQU|reactome:R-HSA-6798695|reactome:R-HSA-9013405|ensembl:ENSG00000130150(gene)|ensembl:ENST00000380492(transcript)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006935"(chemotaxis)|go:"GO:0016020"(membrane)|go:"GO:0035579"(specific granule membrane)|go:"GO:0044232"(organelle membrane contact site) refseq:XP_011513874.1|refseq:NP_114405.1|ensembl:ENSG00000010270(gene)|ensembl:ENST00000009041(transcript)|ensembl:ENST00000396013(transcript)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005768"(endosome)|go:"GO:0005829"(cytosol)|go:"GO:0015485"(cholesterol binding)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0031902"(late endosome membrane)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0044232"(organelle membrane contact site)|go:"GO:0099044"(vesicle tethering to endoplasmic reticulum)|go:"GO:0140284"(endoplasmic reticulum-endosome membrane contact site)|interpro:IPR019498|reactome:R-HSA-196108|refseq:XP_005249937.1|refseq:XP_016868181.1|refseq:XP_016868182.1|refseq:XP_016868183.1 - - - figure legend:Fig. 5C|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells) - 2020/05/21 2020/05/21 rogid:WEdwMYKpu1uQll5NXnMm4P51R4E9606 rogid:Ecl/gQNri850hBVjWGP0Dfnk8ns9606 rigid:QhnYtApi6Lv7Q8xIRyl4FI+98x0 false green fluorescent protein tag:n-n|mutation disrupting interaction strength:404-404,406-406 necessary binding region:208-213|flag tag:?-? - - psi-mi:"MI:0705"(anti tag western blot) psi-mi:"MI:0705"(anti tag western blot) uniprotkb:Q8NHP6 uniprotkb:Q9BXW6 intact:EBI-2812848|uniprotkb:Q8NA83|uniprotkb:Q8N3H2|ensembl:ENSP00000369860 intact:EBI-765918|uniprotkb:Q9BZF5|uniprotkb:Q9NW87|uniprotkb:B7Z7D3|ensembl:ENSP00000320291 psi-mi:mspd2_human(display_long)|uniprotkb:MOSPD2(gene name)|psi-mi:MOSPD2(display_short) psi-mi:osbl1_human(display_long)|uniprotkb:OSBPL1A(gene name)|psi-mi:OSBPL1A(display_short)|uniprotkb:ORP1(gene name synonym)|uniprotkb:OSBP8(gene name synonym)|uniprotkb:OSBPL1(gene name synonym)|uniprotkb:OSBPL1B(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Di et al. (2018) pubmed:29858488|imex:IM-28178 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0486"(UniProt) intact:EBI-25618258|imex:IM-28178-31 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001170946.1|refseq:NP_689794.1|go:"GO:0090023"(positive regulation of neutrophil chemotaxis)|go:"GO:0090026"(positive regulation of monocyte chemotaxis)|go:"GO:0140284"(endoplasmic reticulum-endosome membrane contact site)|interpro:IPR000535(Major sperm protein)|interpro:IPR001251(Cellular retinaldehyde-binding/triple function, C-terminal)|interpro:IPR008962(PapD-like)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR036273|interpro:IPR036865|mint:Q8NHP6|rcsb pdb:6TQS|rcsb pdb:6TQT|rcsb pdb:6TQU|reactome:R-HSA-6798695|reactome:R-HSA-9013405|ensembl:ENSG00000130150(gene)|ensembl:ENST00000380492(transcript)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006935"(chemotaxis)|go:"GO:0016020"(membrane)|go:"GO:0035579"(specific granule membrane)|go:"GO:0044232"(organelle membrane contact site) refseq:NP_001229437.1|refseq:NP_060500.3|refseq:NP_542164.2|refseq:XP_016881022.1|ensembl:ENSG00000141447(gene)|ensembl:ENST00000319481(transcript)|go:"GO:0005543"(phospholipid binding)|go:"GO:0005768"(endosome)|go:"GO:0005770"(late endosome)|go:"GO:0005829"(cytosol)|go:"GO:0006699"(bile acid biosynthetic process)|go:"GO:0008203"(cholesterol metabolic process)|go:"GO:0015248"(sterol transporter activity)|go:"GO:0015485"(cholesterol binding)|go:"GO:0016020"(membrane)|go:"GO:0016192"(vesicle-mediated transport)|go:"GO:0032934"(sterol binding)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0044232"(organelle membrane contact site)|go:"GO:0070062"(extracellular exosome)|interpro:IPR000648(Oxysterol-binding protein)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR002110(Ankyrin)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR018494|interpro:IPR020683|interpro:IPR036770|interpro:IPR037239|mint:Q9BXW6|rcsb pdb:5ZM5|rcsb pdb:5ZM6|rcsb pdb:5ZM7|rcsb pdb:6IYB|rcsb pdb:6TQS|reactome:R-HSA-192105|reactome:R-HSA-2132295|refseq:XP_016881023.1 - - - figure legend:Fig. 5D|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells) - 2020/05/21 2020/05/21 rogid:WEdwMYKpu1uQll5NXnMm4P51R4E9606 rogid:IaZi6kaj9t0aU94PF/XOaxH1dNA9606 rigid:PViNSVICK/WUweVdABQL4nO3CmY false green fluorescent protein tag:n-n|mutation disrupting interaction strength:404-404,406-406 mutation disrupting interaction strength:476-477|flag tag:?-? - - psi-mi:"MI:0705"(anti tag western blot) psi-mi:"MI:0705"(anti tag western blot) uniprotkb:Q8NHP6 uniprotkb:Q9Y5P4 intact:EBI-2812848|uniprotkb:Q8NA83|uniprotkb:Q8N3H2|ensembl:ENSP00000369860 intact:EBI-739994|uniprotkb:Q96Q85|uniprotkb:Q96Q88|uniprotkb:Q9H2S7|uniprotkb:Q9H2S8|uniprotkb:Q53YV1|uniprotkb:Q53YV2|uniprotkb:A8K7S2|uniprotkb:B3KUB7|ensembl:ENSP00000261415|ensembl:ENSP00000494110|ensembl:ENSP00000495760 psi-mi:mspd2_human(display_long)|uniprotkb:MOSPD2(gene name)|psi-mi:MOSPD2(display_short) psi-mi:cert_human(display_long)|uniprotkb:CERT1(gene name)|psi-mi:CERT1(display_short)|uniprotkb:CERT(gene name synonym)|uniprotkb:COL4A3BP(gene name synonym)|uniprotkb:Collagen type IV alpha-3-binding protein(gene name synonym)|uniprotkb:Goodpasture antigen-binding protein(gene name synonym)|uniprotkb:STARD11(gene name synonym)|uniprotkb:START domain-containing protein 11(gene name synonym)|uniprotkb:StAR-related lipid transfer protein 11(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Di et al. (2018) pubmed:29858488|imex:IM-28178 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0486"(UniProt) intact:EBI-25618274|imex:IM-28178-41 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001170946.1|refseq:NP_689794.1|go:"GO:0090023"(positive regulation of neutrophil chemotaxis)|go:"GO:0090026"(positive regulation of monocyte chemotaxis)|go:"GO:0140284"(endoplasmic reticulum-endosome membrane contact site)|interpro:IPR000535(Major sperm protein)|interpro:IPR001251(Cellular retinaldehyde-binding/triple function, C-terminal)|interpro:IPR008962(PapD-like)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR036273|interpro:IPR036865|mint:Q8NHP6|rcsb pdb:6TQS|rcsb pdb:6TQT|rcsb pdb:6TQU|reactome:R-HSA-6798695|reactome:R-HSA-9013405|ensembl:ENSG00000130150(gene)|ensembl:ENST00000380492(transcript)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006935"(chemotaxis)|go:"GO:0016020"(membrane)|go:"GO:0035579"(specific granule membrane)|go:"GO:0044232"(organelle membrane contact site) refseq:NP_001123577.1|refseq:NP_005704.1|refseq:NP_112729.1|refseq:XP_016864408.1|rcsb pdb:2E3P|rcsb pdb:2E3Q|rcsb pdb:2E3R|rcsb pdb:2E3S|rcsb pdb:2RSG|rcsb pdb:2Z9Y|rcsb pdb:2Z9Z|rcsb pdb:3H3Q|rcsb pdb:3H3R|rcsb pdb:3H3S|rcsb pdb:3H3T|rcsb pdb:4HHV|rcsb pdb:5JJD|rcsb pdb:5ZYG|rcsb pdb:5ZYH|rcsb pdb:5ZYI|rcsb pdb:5ZYJ|rcsb pdb:5ZYK|rcsb pdb:5ZYL|rcsb pdb:5ZYM|rcsb pdb:6IEZ|rcsb pdb:6IF0|rcsb pdb:6J0O|rcsb pdb:6J81|reactome:R-HSA-1660661|ensembl:ENSG00000113163(gene)|ensembl:ENST00000261415(transcript)|ensembl:ENST00000643780(transcript)|ensembl:ENST00000644072(transcript)|go:"GO:0000902"(cell morphogenesis)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0003007"(heart morphogenesis)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0006672"(ceramide metabolic process)|go:"GO:0006936"(muscle contraction)|go:"GO:0006955"(immune response)|go:"GO:0007029"(endoplasmic reticulum organization)|go:"GO:0007165"(signal transduction)|go:"GO:0008283"(cell population proliferation)|go:"GO:0016020"(membrane)|go:"GO:0016301"(kinase activity)|go:"GO:0034976"(response to endoplasmic reticulum stress)|go:"GO:0035621"(ER to Golgi ceramide transport)|go:"GO:0035627"(ceramide transport)|go:"GO:0042802"(identical protein binding)|go:"GO:0055088"(lipid homeostasis)|go:"GO:0070273"(phosphatidylinositol-4-phosphate binding)|go:"GO:0070584"(mitochondrion morphogenesis)|go:"GO:0097001"(ceramide binding)|go:"GO:0120009"(intermembrane lipid transfer)|go:"GO:0120012"(intermembrane sphingolipid transfer)|go:"GO:0120017"(ceramide transfer activity)|go:"GO:1902387"(ceramide 1-phosphate binding)|go:"GO:1902388"(ceramide 1-phosphate transfer activity)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR002913(Lipid-binding START)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR023393|interpro:IPR041952|mint:Q9Y5P4|rcsb pdb:2E3M|rcsb pdb:2E3N|rcsb pdb:2E3O|refseq:XP_006714576.1 - - - figure legend:Fig. 5E|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells) - 2020/05/21 2020/05/21 rogid:WEdwMYKpu1uQll5NXnMm4P51R4E9606 rogid:AohUpOJQHInz8f5bKv9/Xb5K+/Y9606 rigid:qrVVz8J42a/cpZ927I2Y0tV9pU8 false green fluorescent protein tag:n-n|mutation disrupting interaction strength:404-404,406-406 mutation disrupting interaction strength:324-324|flag tag:?-? - - psi-mi:"MI:0705"(anti tag western blot) psi-mi:"MI:0705"(anti tag western blot) uniprotkb:Q8NHP6 uniprotkb:Q96TC7 intact:EBI-2812848|uniprotkb:Q8NA83|uniprotkb:Q8N3H2|ensembl:ENSP00000369860 intact:EBI-1056589|uniprotkb:A9UMZ9|uniprotkb:Q6ZWE9|uniprotkb:Q96H23|uniprotkb:Q96SD6|uniprotkb:Q9H6G1|uniprotkb:Q9NVQ6|uniprotkb:B3KRR3|intact:EBI-2563869|ensembl:ENSP00000260385|ensembl:ENSP00000342493 psi-mi:mspd2_human(display_long)|uniprotkb:MOSPD2(gene name)|psi-mi:MOSPD2(display_short) psi-mi:rmd3_human(display_long)|uniprotkb:Protein tyrosine phosphatase-interacting protein 51(gene name synonym)|uniprotkb:TCPTP-interacting protein 51(gene name synonym)|uniprotkb:UNQ3122/PRO10274(orf name)|uniprotkb:hucep-10(orf name)|uniprotkb:RMDN3(gene name)|psi-mi:RMDN3(display_short)|uniprotkb:Cerebral protein 10(gene name synonym)|uniprotkb:FAM82A2(gene name synonym)|uniprotkb:FAM82C(gene name synonym)|uniprotkb:PTPIP51(gene name synonym)|uniprotkb:Protein FAM82A2(gene name synonym)|uniprotkb:Protein FAM82C(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Di et al. (2018) pubmed:29858488|imex:IM-28178 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0486"(UniProt) intact:EBI-25618289|imex:IM-28178-43 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001170946.1|refseq:NP_689794.1|go:"GO:0090023"(positive regulation of neutrophil chemotaxis)|go:"GO:0090026"(positive regulation of monocyte chemotaxis)|go:"GO:0140284"(endoplasmic reticulum-endosome membrane contact site)|interpro:IPR000535(Major sperm protein)|interpro:IPR001251(Cellular retinaldehyde-binding/triple function, C-terminal)|interpro:IPR008962(PapD-like)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR036273|interpro:IPR036865|mint:Q8NHP6|rcsb pdb:6TQS|rcsb pdb:6TQT|rcsb pdb:6TQU|reactome:R-HSA-6798695|reactome:R-HSA-9013405|ensembl:ENSG00000130150(gene)|ensembl:ENST00000380492(transcript)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006935"(chemotaxis)|go:"GO:0016020"(membrane)|go:"GO:0035579"(specific granule membrane)|go:"GO:0044232"(organelle membrane contact site) refseq:NP_060615.1|refseq:NP_001310823.1|refseq:NP_001310824.1|refseq:NP_001291731.1|ensembl:ENSG00000137824(gene)|ensembl:ENST00000260385(transcript)|ensembl:ENST00000338376(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005876"(spindle microtubule)|go:"GO:0006874"(cellular calcium ion homeostasis)|go:"GO:0006915"(apoptotic process)|go:"GO:0008017"(microtubule binding)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030154"(cell differentiation)|go:"GO:0044232"(organelle membrane contact site)|go:"GO:0045171"(intercellular bridge)|go:"GO:0097431"(mitotic spindle pole)|interpro:IPR011990(Tetratricopeptide-like helical)|rcsb pdb:7CC7 - - - figure legend:Fig. 5F|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells) - 2020/05/21 2020/05/21 rogid:WEdwMYKpu1uQll5NXnMm4P51R4E9606 rogid:+y9NPJiIL0BOpjWINH8zcfp5b9o9606 rigid:9i/76CqpJWTIaMhQFNGOdX+Uozs false green fluorescent protein tag:n-n|mutation disrupting interaction strength:404-404,406-406 necessary binding region:157-172|ha tag:?-? - - psi-mi:"MI:0705"(anti tag western blot) psi-mi:"MI:0705"(anti tag western blot) uniprotkb:Q8NHP6 uniprotkb:O95772 intact:EBI-2812848|uniprotkb:Q8NA83|uniprotkb:Q8N3H2|ensembl:ENSP00000369860 intact:EBI-3916943|ensembl:ENSP00000009041|ensembl:ENSP00000379334|uniprotkb:A4D1X0 psi-mi:mspd2_human(display_long)|uniprotkb:MOSPD2(gene name)|psi-mi:MOSPD2(display_short) psi-mi:str3n_human(display_long)|uniprotkb:STARD3NL(gene name)|psi-mi:STARD3NL(display_short)|uniprotkb:MENTHO(gene name synonym)|uniprotkb:MLN64 N-terminal domain homolog(gene name synonym)|uniprotkb:UNQ855/PRO1864(orf name) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Di et al. (2018) pubmed:29858488|imex:IM-28178 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0486"(UniProt) intact:EBI-25618378|imex:IM-28178-33 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001170946.1|refseq:NP_689794.1|go:"GO:0090023"(positive regulation of neutrophil chemotaxis)|go:"GO:0090026"(positive regulation of monocyte chemotaxis)|go:"GO:0140284"(endoplasmic reticulum-endosome membrane contact site)|interpro:IPR000535(Major sperm protein)|interpro:IPR001251(Cellular retinaldehyde-binding/triple function, C-terminal)|interpro:IPR008962(PapD-like)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR036273|interpro:IPR036865|mint:Q8NHP6|rcsb pdb:6TQS|rcsb pdb:6TQT|rcsb pdb:6TQU|reactome:R-HSA-6798695|reactome:R-HSA-9013405|ensembl:ENSG00000130150(gene)|ensembl:ENST00000380492(transcript)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006935"(chemotaxis)|go:"GO:0016020"(membrane)|go:"GO:0035579"(specific granule membrane)|go:"GO:0044232"(organelle membrane contact site) refseq:XP_011513874.1|refseq:NP_114405.1|ensembl:ENSG00000010270(gene)|ensembl:ENST00000009041(transcript)|ensembl:ENST00000396013(transcript)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005768"(endosome)|go:"GO:0005829"(cytosol)|go:"GO:0015485"(cholesterol binding)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0031902"(late endosome membrane)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0044232"(organelle membrane contact site)|go:"GO:0099044"(vesicle tethering to endoplasmic reticulum)|go:"GO:0140284"(endoplasmic reticulum-endosome membrane contact site)|interpro:IPR019498|reactome:R-HSA-196108|refseq:XP_005249937.1|refseq:XP_016868181.1|refseq:XP_016868182.1|refseq:XP_016868183.1 - - - figure legend:Fig. 5G|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells) - 2020/05/21 2020/05/21 rogid:WEdwMYKpu1uQll5NXnMm4P51R4E9606 rogid:Ecl/gQNri850hBVjWGP0Dfnk8ns9606 rigid:QhnYtApi6Lv7Q8xIRyl4FI+98x0 false - necessary binding region:208-213|flag tag:?-? - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:Q8NHP6 uniprotkb:Q14849 intact:EBI-2812848|uniprotkb:Q8NA83|uniprotkb:Q8N3H2|ensembl:ENSP00000369860 intact:EBI-9819324|uniprotkb:A8MXA4|uniprotkb:B4DUY1|uniprotkb:F5H0G2|uniprotkb:Q53Y53|uniprotkb:Q96HM9|ensembl:ENSP00000337446 psi-mi:mspd2_human(display_long)|uniprotkb:MOSPD2(gene name)|psi-mi:MOSPD2(display_short) psi-mi:star3_human(display_long)|uniprotkb:STARD3(gene name)|psi-mi:STARD3(display_short)|uniprotkb:CAB1(gene name synonym)|uniprotkb:MLN64(gene name synonym)|uniprotkb:Metastatic lymph node gene 64 protein(gene name synonym)|uniprotkb:Protein CAB1(gene name synonym)|uniprotkb:START domain-containing protein 3(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Di et al. (2018) pubmed:29858488|imex:IM-28178 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0486"(UniProt) intact:EBI-25618426|imex:IM-28178-35 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001170946.1|refseq:NP_689794.1|go:"GO:0090023"(positive regulation of neutrophil chemotaxis)|go:"GO:0090026"(positive regulation of monocyte chemotaxis)|go:"GO:0140284"(endoplasmic reticulum-endosome membrane contact site)|interpro:IPR000535(Major sperm protein)|interpro:IPR001251(Cellular retinaldehyde-binding/triple function, C-terminal)|interpro:IPR008962(PapD-like)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR036273|interpro:IPR036865|mint:Q8NHP6|rcsb pdb:6TQS|rcsb pdb:6TQT|rcsb pdb:6TQU|reactome:R-HSA-6798695|reactome:R-HSA-9013405|ensembl:ENSG00000130150(gene)|ensembl:ENST00000380492(transcript)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006935"(chemotaxis)|go:"GO:0016020"(membrane)|go:"GO:0035579"(specific granule membrane)|go:"GO:0044232"(organelle membrane contact site) refseq:NP_001159409.1|refseq:NP_001159410.1|refseq:NP_006795.3|refseq:XP_016879530.1|ensembl:ENSG00000131748(gene)|ensembl:ENST00000336308(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005768"(endosome)|go:"GO:0005829"(cytosol)|go:"GO:0006629"(lipid metabolic process)|go:"GO:0006701"(progesterone biosynthetic process)|go:"GO:0006839"(mitochondrial transport)|go:"GO:0008202"(steroid metabolic process)|go:"GO:0008203"(cholesterol metabolic process)|go:"GO:0015485"(cholesterol binding)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030301"(cholesterol transport)|go:"GO:0031902"(late endosome membrane)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0044232"(organelle membrane contact site)|go:"GO:0099044"(vesicle tethering to endoplasmic reticulum)|go:"GO:0120020"(cholesterol transfer activity)|go:"GO:0140284"(endoplasmic reticulum-endosome membrane contact site)|interpro:IPR000799(Steroidogenic acute regulatory protein)|interpro:IPR002913(Lipid-binding START)|interpro:IPR019498|interpro:IPR023393|interpro:IPR029867|rcsb pdb:1EM2|rcsb pdb:2I92|rcsb pdb:5I9J|rcsb pdb:6TQR|rcsb pdb:6TQU|reactome:R-HSA-196108 - - - figure legend:EV2A|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells) - 2020/05/21 2020/05/21 rogid:WEdwMYKpu1uQll5NXnMm4P51R4E9606 rogid:WukBgAECun0AKrfWzBlepgVuZlE9606 rigid:fxnjpASU8QRkHkoYVYWTa804T1U false - mutation disrupting interaction strength:207-208|flag tag:?-? - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:Q8NHP6 uniprotkb:Q9Y5P4 intact:EBI-2812848|uniprotkb:Q8NA83|uniprotkb:Q8N3H2|ensembl:ENSP00000369860 intact:EBI-739994|uniprotkb:Q96Q85|uniprotkb:Q96Q88|uniprotkb:Q9H2S7|uniprotkb:Q9H2S8|uniprotkb:Q53YV1|uniprotkb:Q53YV2|uniprotkb:A8K7S2|uniprotkb:B3KUB7|ensembl:ENSP00000261415|ensembl:ENSP00000494110|ensembl:ENSP00000495760 psi-mi:mspd2_human(display_long)|uniprotkb:MOSPD2(gene name)|psi-mi:MOSPD2(display_short) psi-mi:cert_human(display_long)|uniprotkb:CERT1(gene name)|psi-mi:CERT1(display_short)|uniprotkb:CERT(gene name synonym)|uniprotkb:COL4A3BP(gene name synonym)|uniprotkb:Collagen type IV alpha-3-binding protein(gene name synonym)|uniprotkb:Goodpasture antigen-binding protein(gene name synonym)|uniprotkb:STARD11(gene name synonym)|uniprotkb:START domain-containing protein 11(gene name synonym)|uniprotkb:StAR-related lipid transfer protein 11(gene name synonym) psi-mi:"MI:0663"(confocal microscopy) Di et al. (2018) pubmed:29858488|imex:IM-28178 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0403"(colocalization) psi-mi:"MI:0486"(UniProt) intact:EBI-25618560|imex:IM-28178-15 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001170946.1|refseq:NP_689794.1|go:"GO:0090023"(positive regulation of neutrophil chemotaxis)|go:"GO:0090026"(positive regulation of monocyte chemotaxis)|go:"GO:0140284"(endoplasmic reticulum-endosome membrane contact site)|interpro:IPR000535(Major sperm protein)|interpro:IPR001251(Cellular retinaldehyde-binding/triple function, C-terminal)|interpro:IPR008962(PapD-like)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR036273|interpro:IPR036865|mint:Q8NHP6|rcsb pdb:6TQS|rcsb pdb:6TQT|rcsb pdb:6TQU|reactome:R-HSA-6798695|reactome:R-HSA-9013405|ensembl:ENSG00000130150(gene)|ensembl:ENST00000380492(transcript)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006935"(chemotaxis)|go:"GO:0016020"(membrane)|go:"GO:0035579"(specific granule membrane)|go:"GO:0044232"(organelle membrane contact site) refseq:NP_001123577.1|refseq:NP_005704.1|refseq:NP_112729.1|refseq:XP_016864408.1|rcsb pdb:2E3P|rcsb pdb:2E3Q|rcsb pdb:2E3R|rcsb pdb:2E3S|rcsb pdb:2RSG|rcsb pdb:2Z9Y|rcsb pdb:2Z9Z|rcsb pdb:3H3Q|rcsb pdb:3H3R|rcsb pdb:3H3S|rcsb pdb:3H3T|rcsb pdb:4HHV|rcsb pdb:5JJD|rcsb pdb:5ZYG|rcsb pdb:5ZYH|rcsb pdb:5ZYI|rcsb pdb:5ZYJ|rcsb pdb:5ZYK|rcsb pdb:5ZYL|rcsb pdb:5ZYM|rcsb pdb:6IEZ|rcsb pdb:6IF0|rcsb pdb:6J0O|rcsb pdb:6J81|reactome:R-HSA-1660661|ensembl:ENSG00000113163(gene)|ensembl:ENST00000261415(transcript)|ensembl:ENST00000643780(transcript)|ensembl:ENST00000644072(transcript)|go:"GO:0000902"(cell morphogenesis)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0003007"(heart morphogenesis)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0006672"(ceramide metabolic process)|go:"GO:0006936"(muscle contraction)|go:"GO:0006955"(immune response)|go:"GO:0007029"(endoplasmic reticulum organization)|go:"GO:0007165"(signal transduction)|go:"GO:0008283"(cell population proliferation)|go:"GO:0016020"(membrane)|go:"GO:0016301"(kinase activity)|go:"GO:0034976"(response to endoplasmic reticulum stress)|go:"GO:0035621"(ER to Golgi ceramide transport)|go:"GO:0035627"(ceramide transport)|go:"GO:0042802"(identical protein binding)|go:"GO:0055088"(lipid homeostasis)|go:"GO:0070273"(phosphatidylinositol-4-phosphate binding)|go:"GO:0070584"(mitochondrion morphogenesis)|go:"GO:0097001"(ceramide binding)|go:"GO:0120009"(intermembrane lipid transfer)|go:"GO:0120012"(intermembrane sphingolipid transfer)|go:"GO:0120017"(ceramide transfer activity)|go:"GO:1902387"(ceramide 1-phosphate binding)|go:"GO:1902388"(ceramide 1-phosphate transfer activity)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR002913(Lipid-binding START)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR023393|interpro:IPR041952|mint:Q9Y5P4|rcsb pdb:2E3M|rcsb pdb:2E3N|rcsb pdb:2E3O|refseq:XP_006714576.1 go:"GO:0005794"(Golgi apparatus) - - figure legend:Fig. 6E, EV3C, EV3E|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells) - 2020/05/21 2020/05/21 rogid:WEdwMYKpu1uQll5NXnMm4P51R4E9606 rogid:AohUpOJQHInz8f5bKv9/Xb5K+/Y9606 rigid:qrVVz8J42a/cpZ927I2Y0tV9pU8 false green fluorescent protein tag:n-n|mutation disrupting interaction strength:404-404,406-406 mutation disrupting interaction strength:324-324|flag tag:?-? - - psi-mi:"MI:0867"(tag visualisation by fluorescence) psi-mi:"MI:1201"(anti-tag immunocytochemistry) uniprotkb:Q8NHP6 uniprotkb:Q9BXW6 intact:EBI-2812848|uniprotkb:Q8NA83|uniprotkb:Q8N3H2|ensembl:ENSP00000369860 intact:EBI-765918|uniprotkb:Q9BZF5|uniprotkb:Q9NW87|uniprotkb:B7Z7D3|ensembl:ENSP00000320291 psi-mi:mspd2_human(display_long)|uniprotkb:MOSPD2(gene name)|psi-mi:MOSPD2(display_short) psi-mi:osbl1_human(display_long)|uniprotkb:OSBPL1A(gene name)|psi-mi:OSBPL1A(display_short)|uniprotkb:ORP1(gene name synonym)|uniprotkb:OSBP8(gene name synonym)|uniprotkb:OSBPL1(gene name synonym)|uniprotkb:OSBPL1B(gene name synonym) psi-mi:"MI:0663"(confocal microscopy) Di et al. (2018) pubmed:29858488|imex:IM-28178 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0403"(colocalization) psi-mi:"MI:0486"(UniProt) intact:EBI-25618574|imex:IM-28178-17 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001170946.1|refseq:NP_689794.1|go:"GO:0090023"(positive regulation of neutrophil chemotaxis)|go:"GO:0090026"(positive regulation of monocyte chemotaxis)|go:"GO:0140284"(endoplasmic reticulum-endosome membrane contact site)|interpro:IPR000535(Major sperm protein)|interpro:IPR001251(Cellular retinaldehyde-binding/triple function, C-terminal)|interpro:IPR008962(PapD-like)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR036273|interpro:IPR036865|mint:Q8NHP6|rcsb pdb:6TQS|rcsb pdb:6TQT|rcsb pdb:6TQU|reactome:R-HSA-6798695|reactome:R-HSA-9013405|ensembl:ENSG00000130150(gene)|ensembl:ENST00000380492(transcript)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006935"(chemotaxis)|go:"GO:0016020"(membrane)|go:"GO:0035579"(specific granule membrane)|go:"GO:0044232"(organelle membrane contact site) refseq:NP_001229437.1|refseq:NP_060500.3|refseq:NP_542164.2|refseq:XP_016881022.1|ensembl:ENSG00000141447(gene)|ensembl:ENST00000319481(transcript)|go:"GO:0005543"(phospholipid binding)|go:"GO:0005768"(endosome)|go:"GO:0005770"(late endosome)|go:"GO:0005829"(cytosol)|go:"GO:0006699"(bile acid biosynthetic process)|go:"GO:0008203"(cholesterol metabolic process)|go:"GO:0015248"(sterol transporter activity)|go:"GO:0015485"(cholesterol binding)|go:"GO:0016020"(membrane)|go:"GO:0016192"(vesicle-mediated transport)|go:"GO:0032934"(sterol binding)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0044232"(organelle membrane contact site)|go:"GO:0070062"(extracellular exosome)|interpro:IPR000648(Oxysterol-binding protein)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR002110(Ankyrin)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR018494|interpro:IPR020683|interpro:IPR036770|interpro:IPR037239|mint:Q9BXW6|rcsb pdb:5ZM5|rcsb pdb:5ZM6|rcsb pdb:5ZM7|rcsb pdb:6IYB|rcsb pdb:6TQS|reactome:R-HSA-192105|reactome:R-HSA-2132295|refseq:XP_016881023.1 go:"GO:0005768"(endosome) - - figure legend:Fig. 6D,EV3B, EV3E|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells) - 2020/05/21 2020/05/21 rogid:WEdwMYKpu1uQll5NXnMm4P51R4E9606 rogid:IaZi6kaj9t0aU94PF/XOaxH1dNA9606 rigid:PViNSVICK/WUweVdABQL4nO3CmY false green fluorescent protein tag:n-n|mutation disrupting interaction strength:404-404,406-406 mutation disrupting interaction strength:476-477|flag tag:?-? - - psi-mi:"MI:0867"(tag visualisation by fluorescence) psi-mi:"MI:1201"(anti-tag immunocytochemistry) uniprotkb:Q8NHP6 uniprotkb:Q14849 intact:EBI-2812848|uniprotkb:Q8NA83|uniprotkb:Q8N3H2|ensembl:ENSP00000369860 intact:EBI-9819324|uniprotkb:A8MXA4|uniprotkb:B4DUY1|uniprotkb:F5H0G2|uniprotkb:Q53Y53|uniprotkb:Q96HM9|ensembl:ENSP00000337446 psi-mi:mspd2_human(display_long)|uniprotkb:MOSPD2(gene name)|psi-mi:MOSPD2(display_short) psi-mi:star3_human(display_long)|uniprotkb:STARD3(gene name)|psi-mi:STARD3(display_short)|uniprotkb:CAB1(gene name synonym)|uniprotkb:MLN64(gene name synonym)|uniprotkb:Metastatic lymph node gene 64 protein(gene name synonym)|uniprotkb:Protein CAB1(gene name synonym)|uniprotkb:START domain-containing protein 3(gene name synonym) psi-mi:"MI:0663"(confocal microscopy) Di et al. (2018) pubmed:29858488|imex:IM-28178 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0403"(colocalization) psi-mi:"MI:0486"(UniProt) intact:EBI-25618588|imex:IM-28178-47 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001170946.1|refseq:NP_689794.1|go:"GO:0090023"(positive regulation of neutrophil chemotaxis)|go:"GO:0090026"(positive regulation of monocyte chemotaxis)|go:"GO:0140284"(endoplasmic reticulum-endosome membrane contact site)|interpro:IPR000535(Major sperm protein)|interpro:IPR001251(Cellular retinaldehyde-binding/triple function, C-terminal)|interpro:IPR008962(PapD-like)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR036273|interpro:IPR036865|mint:Q8NHP6|rcsb pdb:6TQS|rcsb pdb:6TQT|rcsb pdb:6TQU|reactome:R-HSA-6798695|reactome:R-HSA-9013405|ensembl:ENSG00000130150(gene)|ensembl:ENST00000380492(transcript)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006935"(chemotaxis)|go:"GO:0016020"(membrane)|go:"GO:0035579"(specific granule membrane)|go:"GO:0044232"(organelle membrane contact site) refseq:NP_001159409.1|refseq:NP_001159410.1|refseq:NP_006795.3|refseq:XP_016879530.1|ensembl:ENSG00000131748(gene)|ensembl:ENST00000336308(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005768"(endosome)|go:"GO:0005829"(cytosol)|go:"GO:0006629"(lipid metabolic process)|go:"GO:0006701"(progesterone biosynthetic process)|go:"GO:0006839"(mitochondrial transport)|go:"GO:0008202"(steroid metabolic process)|go:"GO:0008203"(cholesterol metabolic process)|go:"GO:0015485"(cholesterol binding)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030301"(cholesterol transport)|go:"GO:0031902"(late endosome membrane)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0044232"(organelle membrane contact site)|go:"GO:0099044"(vesicle tethering to endoplasmic reticulum)|go:"GO:0120020"(cholesterol transfer activity)|go:"GO:0140284"(endoplasmic reticulum-endosome membrane contact site)|interpro:IPR000799(Steroidogenic acute regulatory protein)|interpro:IPR002913(Lipid-binding START)|interpro:IPR019498|interpro:IPR023393|interpro:IPR029867|rcsb pdb:1EM2|rcsb pdb:2I92|rcsb pdb:5I9J|rcsb pdb:6TQR|rcsb pdb:6TQU|reactome:R-HSA-196108 go:"GO:0005768"(endosome) - - figure legend:Fig. 6C, EV1C, EV3A, EV3E, Supp. FIg. 2C|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells) - 2020/05/21 2020/05/21 rogid:WEdwMYKpu1uQll5NXnMm4P51R4E9606 rogid:WukBgAECun0AKrfWzBlepgVuZlE9606 rigid:fxnjpASU8QRkHkoYVYWTa804T1U false sufficient binding region:1-492|green fluorescent protein tag:n-n|mutation disrupting interaction strength:404-404,406-406 mutation disrupting interaction strength:207-208|flag tag:?-? - - psi-mi:"MI:0867"(tag visualisation by fluorescence) psi-mi:"MI:1201"(anti-tag immunocytochemistry) uniprotkb:Q8NHP6 uniprotkb:O95772 intact:EBI-2812848|uniprotkb:Q8NA83|uniprotkb:Q8N3H2|ensembl:ENSP00000369860 intact:EBI-3916943|ensembl:ENSP00000009041|ensembl:ENSP00000379334|uniprotkb:A4D1X0 psi-mi:mspd2_human(display_long)|uniprotkb:MOSPD2(gene name)|psi-mi:MOSPD2(display_short) psi-mi:str3n_human(display_long)|uniprotkb:STARD3NL(gene name)|psi-mi:STARD3NL(display_short)|uniprotkb:MENTHO(gene name synonym)|uniprotkb:MLN64 N-terminal domain homolog(gene name synonym)|uniprotkb:UNQ855/PRO1864(orf name) psi-mi:"MI:0663"(confocal microscopy) Di et al. (2018) pubmed:29858488|imex:IM-28178 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0403"(colocalization) psi-mi:"MI:0486"(UniProt) intact:EBI-25618602|imex:IM-28178-49 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001170946.1|refseq:NP_689794.1|go:"GO:0090023"(positive regulation of neutrophil chemotaxis)|go:"GO:0090026"(positive regulation of monocyte chemotaxis)|go:"GO:0140284"(endoplasmic reticulum-endosome membrane contact site)|interpro:IPR000535(Major sperm protein)|interpro:IPR001251(Cellular retinaldehyde-binding/triple function, C-terminal)|interpro:IPR008962(PapD-like)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR036273|interpro:IPR036865|mint:Q8NHP6|rcsb pdb:6TQS|rcsb pdb:6TQT|rcsb pdb:6TQU|reactome:R-HSA-6798695|reactome:R-HSA-9013405|ensembl:ENSG00000130150(gene)|ensembl:ENST00000380492(transcript)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006935"(chemotaxis)|go:"GO:0016020"(membrane)|go:"GO:0035579"(specific granule membrane)|go:"GO:0044232"(organelle membrane contact site) refseq:XP_011513874.1|refseq:NP_114405.1|ensembl:ENSG00000010270(gene)|ensembl:ENST00000009041(transcript)|ensembl:ENST00000396013(transcript)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005768"(endosome)|go:"GO:0005829"(cytosol)|go:"GO:0015485"(cholesterol binding)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0031902"(late endosome membrane)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0044232"(organelle membrane contact site)|go:"GO:0099044"(vesicle tethering to endoplasmic reticulum)|go:"GO:0140284"(endoplasmic reticulum-endosome membrane contact site)|interpro:IPR019498|reactome:R-HSA-196108|refseq:XP_005249937.1|refseq:XP_016868181.1|refseq:XP_016868182.1|refseq:XP_016868183.1 go:"GO:0005768"(endosome) - - figure legend:Fig. 6B,7A-C|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells) - 2020/05/21 2020/05/21 rogid:WEdwMYKpu1uQll5NXnMm4P51R4E9606 rogid:Ecl/gQNri850hBVjWGP0Dfnk8ns9606 rigid:QhnYtApi6Lv7Q8xIRyl4FI+98x0 false green fluorescent protein tag:n-n|mutation disrupting interaction strength:404-404,406-406 necessary binding region:208-213|flag tag:?-? - - psi-mi:"MI:0867"(tag visualisation by fluorescence) psi-mi:"MI:1201"(anti-tag immunocytochemistry) uniprotkb:Q8NHP6 uniprotkb:Q96TC7 intact:EBI-2812848|uniprotkb:Q8NA83|uniprotkb:Q8N3H2|ensembl:ENSP00000369860 intact:EBI-1056589|uniprotkb:A9UMZ9|uniprotkb:Q6ZWE9|uniprotkb:Q96H23|uniprotkb:Q96SD6|uniprotkb:Q9H6G1|uniprotkb:Q9NVQ6|uniprotkb:B3KRR3|intact:EBI-2563869|ensembl:ENSP00000260385|ensembl:ENSP00000342493 psi-mi:mspd2_human(display_long)|uniprotkb:MOSPD2(gene name)|psi-mi:MOSPD2(display_short) psi-mi:rmd3_human(display_long)|uniprotkb:Protein tyrosine phosphatase-interacting protein 51(gene name synonym)|uniprotkb:TCPTP-interacting protein 51(gene name synonym)|uniprotkb:UNQ3122/PRO10274(orf name)|uniprotkb:hucep-10(orf name)|uniprotkb:RMDN3(gene name)|psi-mi:RMDN3(display_short)|uniprotkb:Cerebral protein 10(gene name synonym)|uniprotkb:FAM82A2(gene name synonym)|uniprotkb:FAM82C(gene name synonym)|uniprotkb:PTPIP51(gene name synonym)|uniprotkb:Protein FAM82A2(gene name synonym)|uniprotkb:Protein FAM82C(gene name synonym) psi-mi:"MI:0663"(confocal microscopy) Di et al. (2018) pubmed:29858488|imex:IM-28178 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0403"(colocalization) psi-mi:"MI:0486"(UniProt) intact:EBI-25618616|imex:IM-28178-51 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001170946.1|refseq:NP_689794.1|go:"GO:0090023"(positive regulation of neutrophil chemotaxis)|go:"GO:0090026"(positive regulation of monocyte chemotaxis)|go:"GO:0140284"(endoplasmic reticulum-endosome membrane contact site)|interpro:IPR000535(Major sperm protein)|interpro:IPR001251(Cellular retinaldehyde-binding/triple function, C-terminal)|interpro:IPR008962(PapD-like)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR036273|interpro:IPR036865|mint:Q8NHP6|rcsb pdb:6TQS|rcsb pdb:6TQT|rcsb pdb:6TQU|reactome:R-HSA-6798695|reactome:R-HSA-9013405|ensembl:ENSG00000130150(gene)|ensembl:ENST00000380492(transcript)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006935"(chemotaxis)|go:"GO:0016020"(membrane)|go:"GO:0035579"(specific granule membrane)|go:"GO:0044232"(organelle membrane contact site) refseq:NP_060615.1|refseq:NP_001310823.1|refseq:NP_001310824.1|refseq:NP_001291731.1|ensembl:ENSG00000137824(gene)|ensembl:ENST00000260385(transcript)|ensembl:ENST00000338376(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005876"(spindle microtubule)|go:"GO:0006874"(cellular calcium ion homeostasis)|go:"GO:0006915"(apoptotic process)|go:"GO:0008017"(microtubule binding)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030154"(cell differentiation)|go:"GO:0044232"(organelle membrane contact site)|go:"GO:0045171"(intercellular bridge)|go:"GO:0097431"(mitotic spindle pole)|interpro:IPR011990(Tetratricopeptide-like helical)|rcsb pdb:7CC7 go:"GO:0005739"(mitochondrion) - - figure legend:Fig. 6F EV1D Supp. Fig. 2D|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells) - 2020/05/21 2020/05/21 rogid:WEdwMYKpu1uQll5NXnMm4P51R4E9606 rogid:+y9NPJiIL0BOpjWINH8zcfp5b9o9606 rigid:9i/76CqpJWTIaMhQFNGOdX+Uozs false green fluorescent protein tag:n-n|mutation disrupting interaction strength:404-404,406-406|sufficient binding region:1-492 necessary binding region:157-172|ha tag:?-? - - psi-mi:"MI:0867"(tag visualisation by fluorescence) psi-mi:"MI:0867"(tag visualisation by fluorescence) uniprotkb:Q8NHP6 uniprotkb:Q9P0L0 intact:EBI-2812848|uniprotkb:Q8NA83|uniprotkb:Q8N3H2|ensembl:ENSP00000369860 intact:EBI-1059156|uniprotkb:Q9UBZ2|uniprotkb:O75453|uniprotkb:Q5U0E7|intact:EBI-2556404|uniprotkb:A6NDZ0|intact:EBI-2512000|uniprotkb:D3DUI3|ensembl:ENSP00000382880 psi-mi:mspd2_human(display_long)|uniprotkb:MOSPD2(gene name)|psi-mi:MOSPD2(display_short) psi-mi:vapa_human(display_long)|uniprotkb:VAPA(gene name)|psi-mi:VAPA(display_short)|uniprotkb:VAP33(gene name synonym)|uniprotkb:33 kDa VAMP-associated protein(gene name synonym) psi-mi:"MI:0663"(confocal microscopy) Di et al. (2018) pubmed:29858488|imex:IM-28178 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0403"(colocalization) psi-mi:"MI:0486"(UniProt) intact:EBI-25756242|imex:IM-28178-61 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001170946.1|refseq:NP_689794.1|go:"GO:0090023"(positive regulation of neutrophil chemotaxis)|go:"GO:0090026"(positive regulation of monocyte chemotaxis)|go:"GO:0140284"(endoplasmic reticulum-endosome membrane contact site)|interpro:IPR000535(Major sperm protein)|interpro:IPR001251(Cellular retinaldehyde-binding/triple function, C-terminal)|interpro:IPR008962(PapD-like)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR036273|interpro:IPR036865|mint:Q8NHP6|rcsb pdb:6TQS|rcsb pdb:6TQT|rcsb pdb:6TQU|reactome:R-HSA-6798695|reactome:R-HSA-9013405|ensembl:ENSG00000130150(gene)|ensembl:ENST00000380492(transcript)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006935"(chemotaxis)|go:"GO:0016020"(membrane)|go:"GO:0035579"(specific granule membrane)|go:"GO:0044232"(organelle membrane contact site) refseq:NP_003565.4|refseq:NP_919415.2|dip:DIP-41135N|go:"GO:0031982"(vesicle)|go:"GO:0033149"(FFAT motif binding)|go:"GO:0035577"(azurophil granule membrane)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0044791"(obsolete positive regulation by host of viral release from host cell)|go:"GO:0044828"(negative regulation by host of viral genome replication)|go:"GO:0044829"(positive regulation by host of viral genome replication)|go:"GO:0045296"(cadherin binding)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0061025"(membrane fusion)|go:"GO:0070972"(protein localization to endoplasmic reticulum)|go:"GO:0090114"(COPII-coated vesicle budding)|interpro:IPR000535(Major sperm protein)|interpro:IPR008962(PapD-like)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR016763(Vesicle-associated membrane protein)|mint:Q9P0L0|rcsb pdb:2RR3|rcsb pdb:6TQR|reactome:R-HSA-1660661|reactome:R-HSA-6798695|reactome:R-HSA-9609523|ensembl:ENSG00000101558(gene)|ensembl:ENST00000400000(transcript)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0031175"(neuron projection development)|go:"GO:0031965"(nuclear membrane)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005923"(bicellular tight junction)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0008017"(microtubule binding)|go:"GO:0008219"(cell death)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0016021"(integral component of membrane) go:"GO:0005768"(endosome) - - figure legend:4A|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells) - 2020/05/21 2020/07/15 rogid:WEdwMYKpu1uQll5NXnMm4P51R4E9606 rogid:h8NG5Ak0n6b/iq2yKYMsLsJKpos9606 rigid:/+wRuwOXmeCKJDQ+N7lF2YgSvlI false green fluorescent protein tag:n-n - - - psi-mi:"MI:0867"(tag visualisation by fluorescence) psi-mi:"MI:1200"(immunocytochemistry) uniprotkb:Q8NHP6 uniprotkb:O95772 intact:EBI-2812848|uniprotkb:Q8NA83|uniprotkb:Q8N3H2|ensembl:ENSP00000369860 intact:EBI-3916943|ensembl:ENSP00000009041|ensembl:ENSP00000379334|uniprotkb:A4D1X0 psi-mi:mspd2_human(display_long)|uniprotkb:MOSPD2(gene name)|psi-mi:MOSPD2(display_short) psi-mi:str3n_human(display_long)|uniprotkb:STARD3NL(gene name)|psi-mi:STARD3NL(display_short)|uniprotkb:MENTHO(gene name synonym)|uniprotkb:MLN64 N-terminal domain homolog(gene name synonym)|uniprotkb:UNQ855/PRO1864(orf name) psi-mi:"MI:0663"(confocal microscopy) Di et al. (2018) pubmed:29858488|imex:IM-28178 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0403"(colocalization) psi-mi:"MI:0486"(UniProt) intact:EBI-25618831|imex:IM-28178-53 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001170946.1|refseq:NP_689794.1|go:"GO:0090023"(positive regulation of neutrophil chemotaxis)|go:"GO:0090026"(positive regulation of monocyte chemotaxis)|go:"GO:0140284"(endoplasmic reticulum-endosome membrane contact site)|interpro:IPR000535(Major sperm protein)|interpro:IPR001251(Cellular retinaldehyde-binding/triple function, C-terminal)|interpro:IPR008962(PapD-like)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR036273|interpro:IPR036865|mint:Q8NHP6|rcsb pdb:6TQS|rcsb pdb:6TQT|rcsb pdb:6TQU|reactome:R-HSA-6798695|reactome:R-HSA-9013405|ensembl:ENSG00000130150(gene)|ensembl:ENST00000380492(transcript)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006935"(chemotaxis)|go:"GO:0016020"(membrane)|go:"GO:0035579"(specific granule membrane)|go:"GO:0044232"(organelle membrane contact site) refseq:XP_011513874.1|refseq:NP_114405.1|ensembl:ENSG00000010270(gene)|ensembl:ENST00000009041(transcript)|ensembl:ENST00000396013(transcript)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005768"(endosome)|go:"GO:0005829"(cytosol)|go:"GO:0015485"(cholesterol binding)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0031902"(late endosome membrane)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0044232"(organelle membrane contact site)|go:"GO:0099044"(vesicle tethering to endoplasmic reticulum)|go:"GO:0140284"(endoplasmic reticulum-endosome membrane contact site)|interpro:IPR019498|reactome:R-HSA-196108|refseq:XP_005249937.1|refseq:XP_016868181.1|refseq:XP_016868182.1|refseq:XP_016868183.1 go:"GO:0005768"(endosome) - - figure legend:Fig. 8,|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells) - 2020/05/21 2020/05/22 rogid:WEdwMYKpu1uQll5NXnMm4P51R4E9606 rogid:Ecl/gQNri850hBVjWGP0Dfnk8ns9606 rigid:QhnYtApi6Lv7Q8xIRyl4FI+98x0 false - necessary binding region:208-213|flag tag:?-? - - psi-mi:"MI:1200"(immunocytochemistry) psi-mi:"MI:1201"(anti-tag immunocytochemistry) uniprotkb:Q8NHP6 uniprotkb:Q9Y5P4 intact:EBI-2812848|uniprotkb:Q8NA83|uniprotkb:Q8N3H2|ensembl:ENSP00000369860 intact:EBI-739994|uniprotkb:Q96Q85|uniprotkb:Q96Q88|uniprotkb:Q9H2S7|uniprotkb:Q9H2S8|uniprotkb:Q53YV1|uniprotkb:Q53YV2|uniprotkb:A8K7S2|uniprotkb:B3KUB7|ensembl:ENSP00000261415|ensembl:ENSP00000494110|ensembl:ENSP00000495760 psi-mi:mspd2_human(display_long)|uniprotkb:MOSPD2(gene name)|psi-mi:MOSPD2(display_short) psi-mi:cert_human(display_long)|uniprotkb:CERT1(gene name)|psi-mi:CERT1(display_short)|uniprotkb:CERT(gene name synonym)|uniprotkb:COL4A3BP(gene name synonym)|uniprotkb:Collagen type IV alpha-3-binding protein(gene name synonym)|uniprotkb:Goodpasture antigen-binding protein(gene name synonym)|uniprotkb:STARD11(gene name synonym)|uniprotkb:START domain-containing protein 11(gene name synonym)|uniprotkb:StAR-related lipid transfer protein 11(gene name synonym) psi-mi:"MI:0663"(confocal microscopy) Di et al. (2018) pubmed:29858488|imex:IM-28178 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0403"(colocalization) psi-mi:"MI:0486"(UniProt) intact:EBI-25618852|imex:IM-28178-55 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001170946.1|refseq:NP_689794.1|go:"GO:0090023"(positive regulation of neutrophil chemotaxis)|go:"GO:0090026"(positive regulation of monocyte chemotaxis)|go:"GO:0140284"(endoplasmic reticulum-endosome membrane contact site)|interpro:IPR000535(Major sperm protein)|interpro:IPR001251(Cellular retinaldehyde-binding/triple function, C-terminal)|interpro:IPR008962(PapD-like)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR036273|interpro:IPR036865|mint:Q8NHP6|rcsb pdb:6TQS|rcsb pdb:6TQT|rcsb pdb:6TQU|reactome:R-HSA-6798695|reactome:R-HSA-9013405|ensembl:ENSG00000130150(gene)|ensembl:ENST00000380492(transcript)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006935"(chemotaxis)|go:"GO:0016020"(membrane)|go:"GO:0035579"(specific granule membrane)|go:"GO:0044232"(organelle membrane contact site) refseq:NP_001123577.1|refseq:NP_005704.1|refseq:NP_112729.1|refseq:XP_016864408.1|rcsb pdb:2E3P|rcsb pdb:2E3Q|rcsb pdb:2E3R|rcsb pdb:2E3S|rcsb pdb:2RSG|rcsb pdb:2Z9Y|rcsb pdb:2Z9Z|rcsb pdb:3H3Q|rcsb pdb:3H3R|rcsb pdb:3H3S|rcsb pdb:3H3T|rcsb pdb:4HHV|rcsb pdb:5JJD|rcsb pdb:5ZYG|rcsb pdb:5ZYH|rcsb pdb:5ZYI|rcsb pdb:5ZYJ|rcsb pdb:5ZYK|rcsb pdb:5ZYL|rcsb pdb:5ZYM|rcsb pdb:6IEZ|rcsb pdb:6IF0|rcsb pdb:6J0O|rcsb pdb:6J81|reactome:R-HSA-1660661|ensembl:ENSG00000113163(gene)|ensembl:ENST00000261415(transcript)|ensembl:ENST00000643780(transcript)|ensembl:ENST00000644072(transcript)|go:"GO:0000902"(cell morphogenesis)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0003007"(heart morphogenesis)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0006672"(ceramide metabolic process)|go:"GO:0006936"(muscle contraction)|go:"GO:0006955"(immune response)|go:"GO:0007029"(endoplasmic reticulum organization)|go:"GO:0007165"(signal transduction)|go:"GO:0008283"(cell population proliferation)|go:"GO:0016020"(membrane)|go:"GO:0016301"(kinase activity)|go:"GO:0034976"(response to endoplasmic reticulum stress)|go:"GO:0035621"(ER to Golgi ceramide transport)|go:"GO:0035627"(ceramide transport)|go:"GO:0042802"(identical protein binding)|go:"GO:0055088"(lipid homeostasis)|go:"GO:0070273"(phosphatidylinositol-4-phosphate binding)|go:"GO:0070584"(mitochondrion morphogenesis)|go:"GO:0097001"(ceramide binding)|go:"GO:0120009"(intermembrane lipid transfer)|go:"GO:0120012"(intermembrane sphingolipid transfer)|go:"GO:0120017"(ceramide transfer activity)|go:"GO:1902387"(ceramide 1-phosphate binding)|go:"GO:1902388"(ceramide 1-phosphate transfer activity)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR002913(Lipid-binding START)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR023393|interpro:IPR041952|mint:Q9Y5P4|rcsb pdb:2E3M|rcsb pdb:2E3N|rcsb pdb:2E3O|refseq:XP_006714576.1 go:"GO:0005794"(Golgi apparatus) - - figure legend:EV4E, EV4F|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells) - 2020/05/21 2020/05/22 rogid:WEdwMYKpu1uQll5NXnMm4P51R4E9606 rogid:AohUpOJQHInz8f5bKv9/Xb5K+/Y9606 rigid:qrVVz8J42a/cpZ927I2Y0tV9pU8 false - flag tag:?-?|mutation disrupting interaction strength:324-324 - - psi-mi:"MI:1200"(immunocytochemistry) psi-mi:"MI:1201"(anti-tag immunocytochemistry) uniprotkb:Q8NHP6 uniprotkb:Q9BXW6 intact:EBI-2812848|uniprotkb:Q8NA83|uniprotkb:Q8N3H2|ensembl:ENSP00000369860 intact:EBI-765918|uniprotkb:Q9BZF5|uniprotkb:Q9NW87|uniprotkb:B7Z7D3|ensembl:ENSP00000320291 psi-mi:mspd2_human(display_long)|uniprotkb:MOSPD2(gene name)|psi-mi:MOSPD2(display_short) psi-mi:osbl1_human(display_long)|uniprotkb:OSBPL1A(gene name)|psi-mi:OSBPL1A(display_short)|uniprotkb:ORP1(gene name synonym)|uniprotkb:OSBP8(gene name synonym)|uniprotkb:OSBPL1(gene name synonym)|uniprotkb:OSBPL1B(gene name synonym) psi-mi:"MI:0663"(confocal microscopy) Di et al. (2018) pubmed:29858488|imex:IM-28178 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0403"(colocalization) psi-mi:"MI:0486"(UniProt) intact:EBI-25618866|imex:IM-28178-57 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001170946.1|refseq:NP_689794.1|go:"GO:0090023"(positive regulation of neutrophil chemotaxis)|go:"GO:0090026"(positive regulation of monocyte chemotaxis)|go:"GO:0140284"(endoplasmic reticulum-endosome membrane contact site)|interpro:IPR000535(Major sperm protein)|interpro:IPR001251(Cellular retinaldehyde-binding/triple function, C-terminal)|interpro:IPR008962(PapD-like)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR036273|interpro:IPR036865|mint:Q8NHP6|rcsb pdb:6TQS|rcsb pdb:6TQT|rcsb pdb:6TQU|reactome:R-HSA-6798695|reactome:R-HSA-9013405|ensembl:ENSG00000130150(gene)|ensembl:ENST00000380492(transcript)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006935"(chemotaxis)|go:"GO:0016020"(membrane)|go:"GO:0035579"(specific granule membrane)|go:"GO:0044232"(organelle membrane contact site) refseq:NP_001229437.1|refseq:NP_060500.3|refseq:NP_542164.2|refseq:XP_016881022.1|ensembl:ENSG00000141447(gene)|ensembl:ENST00000319481(transcript)|go:"GO:0005543"(phospholipid binding)|go:"GO:0005768"(endosome)|go:"GO:0005770"(late endosome)|go:"GO:0005829"(cytosol)|go:"GO:0006699"(bile acid biosynthetic process)|go:"GO:0008203"(cholesterol metabolic process)|go:"GO:0015248"(sterol transporter activity)|go:"GO:0015485"(cholesterol binding)|go:"GO:0016020"(membrane)|go:"GO:0016192"(vesicle-mediated transport)|go:"GO:0032934"(sterol binding)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0044232"(organelle membrane contact site)|go:"GO:0070062"(extracellular exosome)|interpro:IPR000648(Oxysterol-binding protein)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR002110(Ankyrin)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR018494|interpro:IPR020683|interpro:IPR036770|interpro:IPR037239|mint:Q9BXW6|rcsb pdb:5ZM5|rcsb pdb:5ZM6|rcsb pdb:5ZM7|rcsb pdb:6IYB|rcsb pdb:6TQS|reactome:R-HSA-192105|reactome:R-HSA-2132295|refseq:XP_016881023.1 go:"GO:0005768"(endosome) - - figure legend:EV4C, EV4D|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells) - 2020/05/21 2020/05/22 rogid:WEdwMYKpu1uQll5NXnMm4P51R4E9606 rogid:IaZi6kaj9t0aU94PF/XOaxH1dNA9606 rigid:PViNSVICK/WUweVdABQL4nO3CmY false green fluorescent protein tag:n-n|mutation disrupting interaction strength:404-404,406-406 mutation disrupting interaction strength:476-477|flag tag:?-? - - psi-mi:"MI:1200"(immunocytochemistry) psi-mi:"MI:1201"(anti-tag immunocytochemistry) uniprotkb:Q8NHP6 uniprotkb:Q96TC7 intact:EBI-2812848|uniprotkb:Q8NA83|uniprotkb:Q8N3H2|ensembl:ENSP00000369860 intact:EBI-1056589|uniprotkb:A9UMZ9|uniprotkb:Q6ZWE9|uniprotkb:Q96H23|uniprotkb:Q96SD6|uniprotkb:Q9H6G1|uniprotkb:Q9NVQ6|uniprotkb:B3KRR3|intact:EBI-2563869|ensembl:ENSP00000260385|ensembl:ENSP00000342493 psi-mi:mspd2_human(display_long)|uniprotkb:MOSPD2(gene name)|psi-mi:MOSPD2(display_short) psi-mi:rmd3_human(display_long)|uniprotkb:Protein tyrosine phosphatase-interacting protein 51(gene name synonym)|uniprotkb:TCPTP-interacting protein 51(gene name synonym)|uniprotkb:UNQ3122/PRO10274(orf name)|uniprotkb:hucep-10(orf name)|uniprotkb:RMDN3(gene name)|psi-mi:RMDN3(display_short)|uniprotkb:Cerebral protein 10(gene name synonym)|uniprotkb:FAM82A2(gene name synonym)|uniprotkb:FAM82C(gene name synonym)|uniprotkb:PTPIP51(gene name synonym)|uniprotkb:Protein FAM82A2(gene name synonym)|uniprotkb:Protein FAM82C(gene name synonym) psi-mi:"MI:0663"(confocal microscopy) Di et al. (2018) pubmed:29858488|imex:IM-28178 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0403"(colocalization) psi-mi:"MI:0486"(UniProt) intact:EBI-25618929|imex:IM-28178-19 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001170946.1|refseq:NP_689794.1|go:"GO:0090023"(positive regulation of neutrophil chemotaxis)|go:"GO:0090026"(positive regulation of monocyte chemotaxis)|go:"GO:0140284"(endoplasmic reticulum-endosome membrane contact site)|interpro:IPR000535(Major sperm protein)|interpro:IPR001251(Cellular retinaldehyde-binding/triple function, C-terminal)|interpro:IPR008962(PapD-like)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR036273|interpro:IPR036865|mint:Q8NHP6|rcsb pdb:6TQS|rcsb pdb:6TQT|rcsb pdb:6TQU|reactome:R-HSA-6798695|reactome:R-HSA-9013405|ensembl:ENSG00000130150(gene)|ensembl:ENST00000380492(transcript)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006935"(chemotaxis)|go:"GO:0016020"(membrane)|go:"GO:0035579"(specific granule membrane)|go:"GO:0044232"(organelle membrane contact site) refseq:NP_060615.1|refseq:NP_001310823.1|refseq:NP_001310824.1|refseq:NP_001291731.1|ensembl:ENSG00000137824(gene)|ensembl:ENST00000260385(transcript)|ensembl:ENST00000338376(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005876"(spindle microtubule)|go:"GO:0006874"(cellular calcium ion homeostasis)|go:"GO:0006915"(apoptotic process)|go:"GO:0008017"(microtubule binding)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030154"(cell differentiation)|go:"GO:0044232"(organelle membrane contact site)|go:"GO:0045171"(intercellular bridge)|go:"GO:0097431"(mitotic spindle pole)|interpro:IPR011990(Tetratricopeptide-like helical)|rcsb pdb:7CC7 go:"GO:0005739"(mitochondrion) - - figure legend:EV4G EV4H|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells) - 2020/05/21 2020/05/22 rogid:WEdwMYKpu1uQll5NXnMm4P51R4E9606 rogid:+y9NPJiIL0BOpjWINH8zcfp5b9o9606 rigid:9i/76CqpJWTIaMhQFNGOdX+Uozs false - necessary binding region:157-172|ha tag:?-? - - psi-mi:"MI:1200"(immunocytochemistry) psi-mi:"MI:1200"(immunocytochemistry) uniprotkb:Q8NHP6 uniprotkb:Q14849 intact:EBI-2812848|uniprotkb:Q8NA83|uniprotkb:Q8N3H2|ensembl:ENSP00000369860 intact:EBI-9819324|uniprotkb:A8MXA4|uniprotkb:B4DUY1|uniprotkb:F5H0G2|uniprotkb:Q53Y53|uniprotkb:Q96HM9|ensembl:ENSP00000337446 psi-mi:mspd2_human(display_long)|uniprotkb:MOSPD2(gene name)|psi-mi:MOSPD2(display_short) psi-mi:star3_human(display_long)|uniprotkb:STARD3(gene name)|psi-mi:STARD3(display_short)|uniprotkb:CAB1(gene name synonym)|uniprotkb:MLN64(gene name synonym)|uniprotkb:Metastatic lymph node gene 64 protein(gene name synonym)|uniprotkb:Protein CAB1(gene name synonym)|uniprotkb:START domain-containing protein 3(gene name synonym) psi-mi:"MI:0663"(confocal microscopy) Di et al. (2018) pubmed:29858488|imex:IM-28178 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0403"(colocalization) psi-mi:"MI:0486"(UniProt) intact:EBI-25618943|imex:IM-28178-39 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001170946.1|refseq:NP_689794.1|go:"GO:0090023"(positive regulation of neutrophil chemotaxis)|go:"GO:0090026"(positive regulation of monocyte chemotaxis)|go:"GO:0140284"(endoplasmic reticulum-endosome membrane contact site)|interpro:IPR000535(Major sperm protein)|interpro:IPR001251(Cellular retinaldehyde-binding/triple function, C-terminal)|interpro:IPR008962(PapD-like)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR036273|interpro:IPR036865|mint:Q8NHP6|rcsb pdb:6TQS|rcsb pdb:6TQT|rcsb pdb:6TQU|reactome:R-HSA-6798695|reactome:R-HSA-9013405|ensembl:ENSG00000130150(gene)|ensembl:ENST00000380492(transcript)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006935"(chemotaxis)|go:"GO:0016020"(membrane)|go:"GO:0035579"(specific granule membrane)|go:"GO:0044232"(organelle membrane contact site) refseq:NP_001159409.1|refseq:NP_001159410.1|refseq:NP_006795.3|refseq:XP_016879530.1|ensembl:ENSG00000131748(gene)|ensembl:ENST00000336308(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005768"(endosome)|go:"GO:0005829"(cytosol)|go:"GO:0006629"(lipid metabolic process)|go:"GO:0006701"(progesterone biosynthetic process)|go:"GO:0006839"(mitochondrial transport)|go:"GO:0008202"(steroid metabolic process)|go:"GO:0008203"(cholesterol metabolic process)|go:"GO:0015485"(cholesterol binding)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030301"(cholesterol transport)|go:"GO:0031902"(late endosome membrane)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0044232"(organelle membrane contact site)|go:"GO:0099044"(vesicle tethering to endoplasmic reticulum)|go:"GO:0120020"(cholesterol transfer activity)|go:"GO:0140284"(endoplasmic reticulum-endosome membrane contact site)|interpro:IPR000799(Steroidogenic acute regulatory protein)|interpro:IPR002913(Lipid-binding START)|interpro:IPR019498|interpro:IPR023393|interpro:IPR029867|rcsb pdb:1EM2|rcsb pdb:2I92|rcsb pdb:5I9J|rcsb pdb:6TQR|rcsb pdb:6TQU|reactome:R-HSA-196108 go:"GO:0005768"(endosome) - - figure legend:EV4A, EV4B|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells) - 2020/05/21 2020/05/22 rogid:WEdwMYKpu1uQll5NXnMm4P51R4E9606 rogid:WukBgAECun0AKrfWzBlepgVuZlE9606 rigid:fxnjpASU8QRkHkoYVYWTa804T1U false - flag tag:?-?|mutation disrupting interaction strength:207-208 - - psi-mi:"MI:1200"(immunocytochemistry) psi-mi:"MI:1201"(anti-tag immunocytochemistry) uniprotkb:Q8NHP6 uniprotkb:Q9P0L0 intact:EBI-2812848|uniprotkb:Q8NA83|uniprotkb:Q8N3H2|ensembl:ENSP00000369860 intact:EBI-1059156|uniprotkb:Q9UBZ2|uniprotkb:O75453|uniprotkb:Q5U0E7|intact:EBI-2556404|uniprotkb:A6NDZ0|intact:EBI-2512000|uniprotkb:D3DUI3|ensembl:ENSP00000382880 psi-mi:mspd2_human(display_long)|uniprotkb:MOSPD2(gene name)|psi-mi:MOSPD2(display_short) psi-mi:vapa_human(display_long)|uniprotkb:VAPA(gene name)|psi-mi:VAPA(display_short)|uniprotkb:VAP33(gene name synonym)|uniprotkb:33 kDa VAMP-associated protein(gene name synonym) psi-mi:"MI:0663"(confocal microscopy) Di et al. (2018) pubmed:29858488|imex:IM-28178 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0403"(colocalization) psi-mi:"MI:0486"(UniProt) intact:EBI-25755417|imex:IM-28178-60 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001170946.1|refseq:NP_689794.1|go:"GO:0090023"(positive regulation of neutrophil chemotaxis)|go:"GO:0090026"(positive regulation of monocyte chemotaxis)|go:"GO:0140284"(endoplasmic reticulum-endosome membrane contact site)|interpro:IPR000535(Major sperm protein)|interpro:IPR001251(Cellular retinaldehyde-binding/triple function, C-terminal)|interpro:IPR008962(PapD-like)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR036273|interpro:IPR036865|mint:Q8NHP6|rcsb pdb:6TQS|rcsb pdb:6TQT|rcsb pdb:6TQU|reactome:R-HSA-6798695|reactome:R-HSA-9013405|ensembl:ENSG00000130150(gene)|ensembl:ENST00000380492(transcript)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006935"(chemotaxis)|go:"GO:0016020"(membrane)|go:"GO:0035579"(specific granule membrane)|go:"GO:0044232"(organelle membrane contact site) refseq:NP_003565.4|refseq:NP_919415.2|dip:DIP-41135N|go:"GO:0031982"(vesicle)|go:"GO:0033149"(FFAT motif binding)|go:"GO:0035577"(azurophil granule membrane)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0044791"(obsolete positive regulation by host of viral release from host cell)|go:"GO:0044828"(negative regulation by host of viral genome replication)|go:"GO:0044829"(positive regulation by host of viral genome replication)|go:"GO:0045296"(cadherin binding)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0061025"(membrane fusion)|go:"GO:0070972"(protein localization to endoplasmic reticulum)|go:"GO:0090114"(COPII-coated vesicle budding)|interpro:IPR000535(Major sperm protein)|interpro:IPR008962(PapD-like)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR016763(Vesicle-associated membrane protein)|mint:Q9P0L0|rcsb pdb:2RR3|rcsb pdb:6TQR|reactome:R-HSA-1660661|reactome:R-HSA-6798695|reactome:R-HSA-9609523|ensembl:ENSG00000101558(gene)|ensembl:ENST00000400000(transcript)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0031175"(neuron projection development)|go:"GO:0031965"(nuclear membrane)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005923"(bicellular tight junction)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0008017"(microtubule binding)|go:"GO:0008219"(cell death)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0016021"(integral component of membrane) go:"GO:0005768"(endosome) - - figure legend:EV5A-C|comment:Endogenous VAP‐A was recruited together with endogenous MOSPD2 around STARD3NL‐positive endosomes.|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells) - 2020/05/21 2020/07/14 rogid:WEdwMYKpu1uQll5NXnMm4P51R4E9606 rogid:h8NG5Ak0n6b/iq2yKYMsLsJKpos9606 rigid:/+wRuwOXmeCKJDQ+N7lF2YgSvlI false - - - - psi-mi:"MI:1200"(immunocytochemistry) psi-mi:"MI:1200"(immunocytochemistry)