#ID(s) interactor A	ID(s) interactor B	Alt. ID(s) interactor A	Alt. ID(s) interactor B	Alias(es) interactor A	Alias(es) interactor B	Interaction detection method(s)	Publication 1st author(s)	Publication Identifier(s)	Taxid interactor A	Taxid interactor B	Interaction type(s)	Source database(s)	Interaction identifier(s)	Confidence value(s)	Expansion method(s)	Biological role(s) interactor A	Biological role(s) interactor B	Experimental role(s) interactor A	Experimental role(s) interactor B	Type(s) interactor A	Type(s) interactor B	Xref(s) interactor A	Xref(s) interactor B	Interaction Xref(s)	Annotation(s) interactor A	Annotation(s) interactor B	Interaction annotation(s)	Host organism(s)	Interaction parameter(s)	Creation date	Update date	Checksum(s) interactor A	Checksum(s) interactor B	Interaction Checksum(s)	Negative	Feature(s) interactor A	Feature(s) interactor B	Stoichiometry(s) interactor A	Stoichiometry(s) interactor B	Identification method participant A	Identification method participant B
uniprotkb:P35637	uniprotkb:P35637	intact:EBI-400434|uniprotkb:Q9H4A8|ensembl:ENSP00000254108	intact:EBI-400434|uniprotkb:Q9H4A8|ensembl:ENSP00000254108	psi-mi:fus_human(display_long)|uniprotkb:FUS(gene name)|psi-mi:FUS(display_short)|uniprotkb:TLS(gene name synonym)|uniprotkb:Oncogene FUS(gene name synonym)|uniprotkb:Oncogene TLS(gene name synonym)|uniprotkb:Translocated in liposarcoma protein(gene name synonym)|uniprotkb:POMp75(gene name synonym)|uniprotkb:75 kDa DNA-pairing protein(gene name synonym)	psi-mi:fus_human(display_long)|uniprotkb:FUS(gene name)|psi-mi:FUS(display_short)|uniprotkb:TLS(gene name synonym)|uniprotkb:Oncogene FUS(gene name synonym)|uniprotkb:Oncogene TLS(gene name synonym)|uniprotkb:Translocated in liposarcoma protein(gene name synonym)|uniprotkb:POMp75(gene name synonym)|uniprotkb:75 kDa DNA-pairing protein(gene name synonym)	psi-mi:"MI:0894"(electron diffraction)	Luo et al. (2018)	pubmed:29610493|imex:IM-27662	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0465"(DIP)	intact:EBI-25398464|imex:IM-27662-1	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001164105.1|refseq:NP_004951.1|ensembl:ENSG00000089280(gene)|ensembl:ENST00000254108(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0003723"(RNA binding)|go:"GO:0003730"(mRNA 3'-UTR binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005844"(polysome)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0008380"(RNA splicing)|go:"GO:0030331"(estrogen receptor binding)|go:"GO:0031489"(myosin V binding)|go:"GO:0035255"(ionotropic glutamate receptor binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0043204"(perikaryon)|go:"GO:0043484"(regulation of RNA splicing)|go:"GO:0044327"(dendritic spine head)|go:"GO:0046872"(metal ion binding)|go:"GO:0046965"(retinoid X receptor binding)|go:"GO:0046966"(thyroid hormone receptor binding)|go:"GO:0048255"(mRNA stabilization)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051260"(protein homooligomerization)|go:"GO:0071277"(cellular response to calcium ion)|go:"GO:1905168"(positive regulation of double-strand break repair via homologous recombination)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR001876(Zinc finger, RanBP2-type)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR034459|interpro:IPR034870|interpro:IPR035979|interpro:IPR036443|mint:P35637|rcsb pdb:2LA6|rcsb pdb:2LCW|rcsb pdb:4FDD|rcsb pdb:4FQ3|rcsb pdb:5W3N|rcsb pdb:5XRR|rcsb pdb:5XSG|rcsb pdb:5YVG|rcsb pdb:5YVH|rcsb pdb:5YVI|rcsb pdb:6BWZ|rcsb pdb:6BXV|rcsb pdb:6BZP|rcsb pdb:6G99|rcsb pdb:6GBM|rcsb pdb:6KJ1|rcsb pdb:6KJ2|rcsb pdb:6KJ3|rcsb pdb:6KJ4|rcsb pdb:6SNJ|rcsb pdb:6XFM|rcsb pdb:7CYL|reactome:R-HSA-72163|dip:DIP-29857N|go:"GO:0051260"(protein homooligomerization)	refseq:NP_001164105.1|refseq:NP_004951.1|ensembl:ENSG00000089280(gene)|ensembl:ENST00000254108(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0003723"(RNA binding)|go:"GO:0003730"(mRNA 3'-UTR binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005844"(polysome)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0008380"(RNA splicing)|go:"GO:0030331"(estrogen receptor binding)|go:"GO:0031489"(myosin V binding)|go:"GO:0035255"(ionotropic glutamate receptor binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0043204"(perikaryon)|go:"GO:0043484"(regulation of RNA splicing)|go:"GO:0044327"(dendritic spine head)|go:"GO:0046872"(metal ion binding)|go:"GO:0046965"(retinoid X receptor binding)|go:"GO:0046966"(thyroid hormone receptor binding)|go:"GO:0048255"(mRNA stabilization)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051260"(protein homooligomerization)|go:"GO:0071277"(cellular response to calcium ion)|go:"GO:1905168"(positive regulation of double-strand break repair via homologous recombination)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR001876(Zinc finger, RanBP2-type)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR034459|interpro:IPR034870|interpro:IPR035979|interpro:IPR036443|mint:P35637|rcsb pdb:2LA6|rcsb pdb:2LCW|rcsb pdb:4FDD|rcsb pdb:4FQ3|rcsb pdb:5W3N|rcsb pdb:5XRR|rcsb pdb:5XSG|rcsb pdb:5YVG|rcsb pdb:5YVH|rcsb pdb:5YVI|rcsb pdb:6BWZ|rcsb pdb:6BXV|rcsb pdb:6BZP|rcsb pdb:6G99|rcsb pdb:6GBM|rcsb pdb:6KJ1|rcsb pdb:6KJ2|rcsb pdb:6KJ3|rcsb pdb:6KJ4|rcsb pdb:6SNJ|rcsb pdb:6XFM|rcsb pdb:7CYL|reactome:R-HSA-72163|dip:DIP-29857N	wwpdb:5XSG(see-also)	-	-	figure legend:Fig 2, Table 1, Supplementary Fig 2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2020/01/15	2020/01/24	rogid:HUP4fGXQyJnm5CFTuwjTpiucZOc9606	rogid:HUP4fGXQyJnm5CFTuwjTpiucZOc9606	rigid:hUNcXPgeNcWMCPrz2dk/4dYQi70	false	binding-associated region:37-42	binding-associated region:37-42	-	-	psi-mi:"MI:0396"(predetermined participant)|psi-mi:"MI:2287"(identification by structure determination)	psi-mi:"MI:0396"(predetermined participant)|psi-mi:"MI:2287"(identification by structure determination)
uniprotkb:P35637	uniprotkb:P35637	intact:EBI-400434|uniprotkb:Q9H4A8|ensembl:ENSP00000254108	intact:EBI-400434|uniprotkb:Q9H4A8|ensembl:ENSP00000254108	psi-mi:fus_human(display_long)|uniprotkb:FUS(gene name)|psi-mi:FUS(display_short)|uniprotkb:TLS(gene name synonym)|uniprotkb:Oncogene FUS(gene name synonym)|uniprotkb:Oncogene TLS(gene name synonym)|uniprotkb:Translocated in liposarcoma protein(gene name synonym)|uniprotkb:POMp75(gene name synonym)|uniprotkb:75 kDa DNA-pairing protein(gene name synonym)	psi-mi:fus_human(display_long)|uniprotkb:FUS(gene name)|psi-mi:FUS(display_short)|uniprotkb:TLS(gene name synonym)|uniprotkb:Oncogene FUS(gene name synonym)|uniprotkb:Oncogene TLS(gene name synonym)|uniprotkb:Translocated in liposarcoma protein(gene name synonym)|uniprotkb:POMp75(gene name synonym)|uniprotkb:75 kDa DNA-pairing protein(gene name synonym)	psi-mi:"MI:0114"(x-ray crystallography)	Luo et al. (2018)	pubmed:29610493|imex:IM-27662	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0465"(DIP)	intact:EBI-25398482|imex:IM-27662-3	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001164105.1|refseq:NP_004951.1|ensembl:ENSG00000089280(gene)|ensembl:ENST00000254108(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0003723"(RNA binding)|go:"GO:0003730"(mRNA 3'-UTR binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005844"(polysome)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0008380"(RNA splicing)|go:"GO:0030331"(estrogen receptor binding)|go:"GO:0031489"(myosin V binding)|go:"GO:0035255"(ionotropic glutamate receptor binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0043204"(perikaryon)|go:"GO:0043484"(regulation of RNA splicing)|go:"GO:0044327"(dendritic spine head)|go:"GO:0046872"(metal ion binding)|go:"GO:0046965"(retinoid X receptor binding)|go:"GO:0046966"(thyroid hormone receptor binding)|go:"GO:0048255"(mRNA stabilization)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051260"(protein homooligomerization)|go:"GO:0071277"(cellular response to calcium ion)|go:"GO:1905168"(positive regulation of double-strand break repair via homologous recombination)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR001876(Zinc finger, RanBP2-type)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR034459|interpro:IPR034870|interpro:IPR035979|interpro:IPR036443|mint:P35637|rcsb pdb:2LA6|rcsb pdb:2LCW|rcsb pdb:4FDD|rcsb pdb:4FQ3|rcsb pdb:5W3N|rcsb pdb:5XRR|rcsb pdb:5XSG|rcsb pdb:5YVG|rcsb pdb:5YVH|rcsb pdb:5YVI|rcsb pdb:6BWZ|rcsb pdb:6BXV|rcsb pdb:6BZP|rcsb pdb:6G99|rcsb pdb:6GBM|rcsb pdb:6KJ1|rcsb pdb:6KJ2|rcsb pdb:6KJ3|rcsb pdb:6KJ4|rcsb pdb:6SNJ|rcsb pdb:6XFM|rcsb pdb:7CYL|reactome:R-HSA-72163|dip:DIP-29857N|go:"GO:0051260"(protein homooligomerization)	refseq:NP_001164105.1|refseq:NP_004951.1|ensembl:ENSG00000089280(gene)|ensembl:ENST00000254108(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0003723"(RNA binding)|go:"GO:0003730"(mRNA 3'-UTR binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005844"(polysome)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0008380"(RNA splicing)|go:"GO:0030331"(estrogen receptor binding)|go:"GO:0031489"(myosin V binding)|go:"GO:0035255"(ionotropic glutamate receptor binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0043204"(perikaryon)|go:"GO:0043484"(regulation of RNA splicing)|go:"GO:0044327"(dendritic spine head)|go:"GO:0046872"(metal ion binding)|go:"GO:0046965"(retinoid X receptor binding)|go:"GO:0046966"(thyroid hormone receptor binding)|go:"GO:0048255"(mRNA stabilization)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051260"(protein homooligomerization)|go:"GO:0071277"(cellular response to calcium ion)|go:"GO:1905168"(positive regulation of double-strand break repair via homologous recombination)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR001876(Zinc finger, RanBP2-type)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR034459|interpro:IPR034870|interpro:IPR035979|interpro:IPR036443|mint:P35637|rcsb pdb:2LA6|rcsb pdb:2LCW|rcsb pdb:4FDD|rcsb pdb:4FQ3|rcsb pdb:5W3N|rcsb pdb:5XRR|rcsb pdb:5XSG|rcsb pdb:5YVG|rcsb pdb:5YVH|rcsb pdb:5YVI|rcsb pdb:6BWZ|rcsb pdb:6BXV|rcsb pdb:6BZP|rcsb pdb:6G99|rcsb pdb:6GBM|rcsb pdb:6KJ1|rcsb pdb:6KJ2|rcsb pdb:6KJ3|rcsb pdb:6KJ4|rcsb pdb:6SNJ|rcsb pdb:6XFM|rcsb pdb:7CYL|reactome:R-HSA-72163|dip:DIP-29857N	wwpdb:5XRR(see-also)	-	-	figure legend:Fig 3, Table 1, Supplementary Fig 2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2020/01/15	2020/01/24	rogid:HUP4fGXQyJnm5CFTuwjTpiucZOc9606	rogid:HUP4fGXQyJnm5CFTuwjTpiucZOc9606	rigid:hUNcXPgeNcWMCPrz2dk/4dYQi70	false	binding-associated region:54-59	binding-associated region:54-59	-	-	psi-mi:"MI:2287"(identification by structure determination)	psi-mi:"MI:0396"(predetermined participant)|psi-mi:"MI:2287"(identification by structure determination)