#ID(s) interactor A	ID(s) interactor B	Alt. ID(s) interactor A	Alt. ID(s) interactor B	Alias(es) interactor A	Alias(es) interactor B	Interaction detection method(s)	Publication 1st author(s)	Publication Identifier(s)	Taxid interactor A	Taxid interactor B	Interaction type(s)	Source database(s)	Interaction identifier(s)	Confidence value(s)	Expansion method(s)	Biological role(s) interactor A	Biological role(s) interactor B	Experimental role(s) interactor A	Experimental role(s) interactor B	Type(s) interactor A	Type(s) interactor B	Xref(s) interactor A	Xref(s) interactor B	Interaction Xref(s)	Annotation(s) interactor A	Annotation(s) interactor B	Interaction annotation(s)	Host organism(s)	Interaction parameter(s)	Creation date	Update date	Checksum(s) interactor A	Checksum(s) interactor B	Interaction Checksum(s)	Negative	Feature(s) interactor A	Feature(s) interactor B	Stoichiometry(s) interactor A	Stoichiometry(s) interactor B	Identification method participant A	Identification method participant B
uniprotkb:Q16563	uniprotkb:Q92685	intact:EBI-2800683|uniprotkb:A4D0R2|uniprotkb:Q96AR8|ensembl:ENSP00000011473	intact:EBI-2848814|uniprotkb:A8JZZ6|uniprotkb:Q9BT71|ensembl:ENSP00000380793	psi-mi:sypl1_human(display_long)|uniprotkb:SYPL(gene name synonym)|uniprotkb:Pantophysin(gene name synonym)|uniprotkb:SYPL1(gene name)|psi-mi:SYPL1(display_short)	psi-mi:alg3_human(display_long)|uniprotkb:ALG3(gene name)|psi-mi:ALG3(display_short)|uniprotkb:Asparagine-linked glycosylation protein 3 homolog(gene name synonym)|uniprotkb:"Dol-P-Man-dependent alpha(1-3)-mannosyltransferase"(gene name synonym)|uniprotkb:"Dolichyl-P-Man:Man(5)GlcNAc(2)-PP-dolichyl mannosyltransferase"(gene name synonym)|uniprotkb:Dolichyl-phosphate-mannose--glycolipid alpha-mannosyltransferase(gene name synonym)|uniprotkb:NOT(gene name synonym)|uniprotkb:NOT56L(gene name synonym)|uniprotkb:Not56-like protein(gene name synonym)	psi-mi:"MI:0018"(two hybrid)	Hacker et al. (2018)	imex:IM-28062|pubmed:29547901	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0486"(UniProt)	intact:EBI-25467862|imex:IM-28062-21	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_006745.1|refseq:NP_874384.1|ensembl:ENSG00000008282(gene)|ensembl:ENST00000011473(transcript)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0007268"(chemical synaptic transmission)|go:"GO:0016021"(integral component of membrane)|go:"GO:0017075"(syntaxin-1 binding)|go:"GO:0030141"(secretory granule)|go:"GO:0030285"(integral component of synaptic vesicle membrane)|go:"GO:0030672"(synaptic vesicle membrane)|go:"GO:0042470"(melanosome)|go:"GO:0070062"(extracellular exosome)|interpro:IPR001285(Synaptophysin/synaptoporin)|interpro:IPR008253(Marvel)	refseq:NP_005778.1|refseq:NP_001006942.1|ensembl:ENSG00000214160(gene)|ensembl:ENST00000397676(transcript)|go:"GO:0000033"(alpha-1,3-mannosyltransferase activity)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006486"(protein glycosylation)|go:"GO:0006488"(dolichol-linked oligosaccharide biosynthetic process)|go:"GO:0016021"(integral component of membrane)|go:"GO:0052925"("dol-P-Man:Man(5)GlcNAc(2)-PP-Dol alpha-1,3-mannosyltransferase activity")|interpro:IPR007873(ALG3)|reactome:R-HSA-446193|reactome:R-HSA-4720475	-	-	-	figure legend:Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2020/03/10	2020/03/10	rogid:kw4EuKqd6PhotpKiicCjB99ZZCY9606	rogid:/aBCE7QqVCyHZDzq3oSoqtiDlBI9606	rigid:WMFKhUtiSytCPyyngVcH591AMks	false	sufficient binding region:173-241	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q07954	uniprotkb:Q92685	intact:EBI-1046087|uniprotkb:Q8IVG8|uniprotkb:Q2PP12|uniprotkb:Q86SW0|ensembl:ENSP00000243077	intact:EBI-2848814|uniprotkb:A8JZZ6|uniprotkb:Q9BT71|ensembl:ENSP00000380793	psi-mi:lrp1_human(display_long)|uniprotkb:Alpha-2-macroglobulin receptor(gene name synonym)|uniprotkb:Apolipoprotein E receptor(gene name synonym)|uniprotkb:LRP1(gene name)|psi-mi:LRP1(display_short)|uniprotkb:A2MR(gene name synonym)|uniprotkb:APR(gene name synonym)	psi-mi:alg3_human(display_long)|uniprotkb:ALG3(gene name)|psi-mi:ALG3(display_short)|uniprotkb:Asparagine-linked glycosylation protein 3 homolog(gene name synonym)|uniprotkb:"Dol-P-Man-dependent alpha(1-3)-mannosyltransferase"(gene name synonym)|uniprotkb:"Dolichyl-P-Man:Man(5)GlcNAc(2)-PP-dolichyl mannosyltransferase"(gene name synonym)|uniprotkb:Dolichyl-phosphate-mannose--glycolipid alpha-mannosyltransferase(gene name synonym)|uniprotkb:NOT(gene name synonym)|uniprotkb:NOT56L(gene name synonym)|uniprotkb:Not56-like protein(gene name synonym)	psi-mi:"MI:0018"(two hybrid)	Hacker et al. (2018)	imex:IM-28062|pubmed:29547901	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0486"(UniProt)	intact:EBI-25468269|imex:IM-28062-1	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_002323.2|ensembl:ENSG00000123384(gene)|ensembl:ENST00000243077(transcript)|go:"GO:0001523"(retinoid metabolic process)|go:"GO:0001540"(amyloid-beta binding)|go:"GO:0002020"(protease binding)|go:"GO:0002265"(astrocyte activation involved in immune response)|go:"GO:0003723"(RNA binding)|go:"GO:0005041"(low-density lipoprotein particle receptor activity)|go:"GO:0005044"(scavenger receptor activity)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005634"(nucleus)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005769"(early endosome)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0005905"(clathrin-coated pit)|go:"GO:0005925"(focal adhesion)|go:"GO:0006629"(lipid metabolic process)|go:"GO:0006898"(receptor-mediated endocytosis)|go:"GO:0006909"(phagocytosis)|go:"GO:0007041"(lysosomal transport)|go:"GO:0007204"(positive regulation of cytosolic calcium ion concentration)|go:"GO:0007205"(protein kinase C-activating G protein-coupled receptor signaling pathway)|go:"GO:0007568"(aging)|go:"GO:0008283"(cell population proliferation)|go:"GO:0010715"(regulation of extracellular matrix disassembly)|go:"GO:0010875"(positive regulation of cholesterol efflux)|go:"GO:0010942"(positive regulation of cell death)|go:"GO:0010977"(negative regulation of neuron projection development)|go:"GO:0014912"(negative regulation of smooth muscle cell migration)|go:"GO:0015026"(coreceptor activity)|go:"GO:0016020"(membrane)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016964"(alpha-2 macroglobulin receptor activity)|go:"GO:0021987"(cerebral cortex development)|go:"GO:0030136"(clathrin-coated vesicle)|go:"GO:0030178"(negative regulation of Wnt signaling pathway)|go:"GO:0030226"(apolipoprotein receptor activity)|go:"GO:0030425"(dendrite)|go:"GO:0030666"(endocytic vesicle membrane)|go:"GO:0031623"(receptor internalization)|go:"GO:0032050"(clathrin heavy chain binding)|go:"GO:0032092"(positive regulation of protein binding)|go:"GO:0032370"(positive regulation of lipid transport)|go:"GO:0032374"(regulation of cholesterol transport)|go:"GO:0032429"(regulation of phospholipase A2 activity)|go:"GO:0032593"(insulin-responsive compartment)|go:"GO:0032956"(regulation of actin cytoskeleton organization)|go:"GO:0034185"(apolipoprotein binding)|go:"GO:0035774"(positive regulation of insulin secretion involved in cellular response to glucose stimulus)|go:"GO:0035909"(aorta morphogenesis)|go:"GO:0038023"(signaling receptor activity)|go:"GO:0038024"(cargo receptor activity)|go:"GO:0042157"(lipoprotein metabolic process)|go:"GO:0042953"(lipoprotein transport)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043235"(receptor complex)|go:"GO:0043277"(apoptotic cell clearance)|go:"GO:0043395"(heparan sulfate proteoglycan binding)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0044242"(cellular lipid catabolic process)|go:"GO:0044295"(axonal growth cone)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045056"(transcytosis)|go:"GO:0045177"(apical part of cell)|go:"GO:0045807"(positive regulation of endocytosis)|go:"GO:0048691"(positive regulation of axon extension involved in regeneration)|go:"GO:0048694"(positive regulation of collateral sprouting of injured axon)|go:"GO:0050766"(positive regulation of phagocytosis)|go:"GO:0051481"(negative regulation of cytosolic calcium ion concentration)|go:"GO:0051895"(negative regulation of focal adhesion assembly)|go:"GO:0061642"(chemoattraction of axon)|go:"GO:0070325"(lipoprotein particle receptor binding)|go:"GO:0070374"(positive regulation of ERK1 and ERK2 cascade)|go:"GO:0097242"(amyloid-beta clearance)|go:"GO:0098797"(plasma membrane protein complex)|go:"GO:0150093"(amyloid-beta clearance by transcytosis)|go:"GO:0150094"(amyloid-beta clearance by cellular catabolic process)|go:"GO:0150104"(transport across blood-brain barrier)|go:"GO:1900149"(positive regulation of Schwann cell migration)|go:"GO:1900223"(positive regulation of amyloid-beta clearance)|go:"GO:1903078"(positive regulation of protein localization to plasma membrane)|go:"GO:1904109"(positive regulation of cholesterol import)|go:"GO:1904300"(positive regulation of transcytosis)|go:"GO:1904646"(cellular response to amyloid-beta)|go:"GO:1904754"(positive regulation of vascular associated smooth muscle cell migration)|go:"GO:1905049"(negative regulation of metallopeptidase activity)|go:"GO:1905167"(positive regulation of lysosomal protein catabolic process)|go:"GO:2000343"("positive regulation of chemokine (C-X-C motif) ligand 2 production")|go:"GO:2000587"(negative regulation of platelet-derived growth factor receptor-beta signaling pathway)|interpro:IPR000033(Low-density lipoprotein receptor, YWTD repeat)|interpro:IPR000152(Aspartic acid and asparagine hydroxylation site)|interpro:IPR000742(EGF-like, type 3)|interpro:IPR001881(EGF-like calcium-binding)|interpro:IPR002172(Low density lipoprotein-receptor, class A, cysteine-rich)|interpro:IPR009030(Growth factor, receptor)|interpro:IPR011042(Six-bladed beta-propeller, TolB-like)|interpro:IPR018097|interpro:IPR023415|interpro:IPR026823|interpro:IPR032485|interpro:IPR036055|rcsb pdb:1CR8|rcsb pdb:1D2L|rcsb pdb:1J8E|rcsb pdb:2FYJ|rcsb pdb:2FYL|rcsb pdb:2KNX|rcsb pdb:2KNY|reactome:R-HSA-2168880|reactome:R-HSA-975634|dip:DIP-50613N	refseq:NP_005778.1|refseq:NP_001006942.1|ensembl:ENSG00000214160(gene)|ensembl:ENST00000397676(transcript)|go:"GO:0000033"(alpha-1,3-mannosyltransferase activity)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006486"(protein glycosylation)|go:"GO:0006488"(dolichol-linked oligosaccharide biosynthetic process)|go:"GO:0016021"(integral component of membrane)|go:"GO:0052925"("dol-P-Man:Man(5)GlcNAc(2)-PP-Dol alpha-1,3-mannosyltransferase activity")|interpro:IPR007873(ALG3)|reactome:R-HSA-446193|reactome:R-HSA-4720475	-	-	-	figure legend:Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2020/03/10	2020/03/11	rogid:eO2l3huuq6NYoVoYdoCloLqrlRw9606	rogid:/aBCE7QqVCyHZDzq3oSoqtiDlBI9606	rigid:5jwXp6F4jem1jUwalMcPe6u+NL8	false	sufficient binding region:4280-4530	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q9P0L0	uniprotkb:Q92685	intact:EBI-1059156|uniprotkb:Q9UBZ2|uniprotkb:O75453|uniprotkb:Q5U0E7|intact:EBI-2556404|uniprotkb:A6NDZ0|intact:EBI-2512000|uniprotkb:D3DUI3|ensembl:ENSP00000382880	intact:EBI-2848814|uniprotkb:A8JZZ6|uniprotkb:Q9BT71|ensembl:ENSP00000380793	psi-mi:vapa_human(display_long)|uniprotkb:VAPA(gene name)|psi-mi:VAPA(display_short)|uniprotkb:VAP33(gene name synonym)|uniprotkb:33 kDa VAMP-associated protein(gene name synonym)	psi-mi:alg3_human(display_long)|uniprotkb:ALG3(gene name)|psi-mi:ALG3(display_short)|uniprotkb:Asparagine-linked glycosylation protein 3 homolog(gene name synonym)|uniprotkb:"Dol-P-Man-dependent alpha(1-3)-mannosyltransferase"(gene name synonym)|uniprotkb:"Dolichyl-P-Man:Man(5)GlcNAc(2)-PP-dolichyl mannosyltransferase"(gene name synonym)|uniprotkb:Dolichyl-phosphate-mannose--glycolipid alpha-mannosyltransferase(gene name synonym)|uniprotkb:NOT(gene name synonym)|uniprotkb:NOT56L(gene name synonym)|uniprotkb:Not56-like protein(gene name synonym)	psi-mi:"MI:0018"(two hybrid)	Hacker et al. (2018)	imex:IM-28062|pubmed:29547901	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0486"(UniProt)	intact:EBI-25468275|imex:IM-28062-23	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_003565.4|refseq:NP_919415.2|dip:DIP-41135N|go:"GO:0031982"(vesicle)|go:"GO:0033149"(FFAT motif binding)|go:"GO:0035577"(azurophil granule membrane)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0044791"(obsolete positive regulation by host of viral release from host cell)|go:"GO:0044828"(negative regulation by host of viral genome replication)|go:"GO:0044829"(positive regulation by host of viral genome replication)|go:"GO:0045296"(cadherin binding)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0061025"(membrane fusion)|go:"GO:0070972"(protein localization to endoplasmic reticulum)|go:"GO:0090114"(COPII-coated vesicle budding)|interpro:IPR000535(Major sperm protein)|interpro:IPR008962(PapD-like)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR016763(Vesicle-associated membrane protein)|mint:Q9P0L0|rcsb pdb:2RR3|rcsb pdb:6TQR|reactome:R-HSA-1660661|reactome:R-HSA-6798695|reactome:R-HSA-9609523|ensembl:ENSG00000101558(gene)|ensembl:ENST00000400000(transcript)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0031175"(neuron projection development)|go:"GO:0031965"(nuclear membrane)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005923"(bicellular tight junction)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0008017"(microtubule binding)|go:"GO:0008219"(cell death)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0016021"(integral component of membrane)	refseq:NP_005778.1|refseq:NP_001006942.1|ensembl:ENSG00000214160(gene)|ensembl:ENST00000397676(transcript)|go:"GO:0000033"(alpha-1,3-mannosyltransferase activity)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006486"(protein glycosylation)|go:"GO:0006488"(dolichol-linked oligosaccharide biosynthetic process)|go:"GO:0016021"(integral component of membrane)|go:"GO:0052925"("dol-P-Man:Man(5)GlcNAc(2)-PP-Dol alpha-1,3-mannosyltransferase activity")|interpro:IPR007873(ALG3)|reactome:R-HSA-446193|reactome:R-HSA-4720475	-	-	-	figure legend:Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2020/03/10	2020/03/11	rogid:h8NG5Ak0n6b/iq2yKYMsLsJKpos9606	rogid:/aBCE7QqVCyHZDzq3oSoqtiDlBI9606	rigid:oU37uEWOHZWWr7kLboDvhPVpnR0	false	sufficient binding region:117-249	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P78539	uniprotkb:Q92685	intact:EBI-2371213|uniprotkb:Q4VX66|uniprotkb:Q99652|uniprotkb:Q99913|uniprotkb:A8K065|uniprotkb:B4DQH5|uniprotkb:B4DDB8|uniprotkb:F5H4D7|uniprotkb:B3KWP8|uniprotkb:G3V1L0|ensembl:ENSP00000367794	intact:EBI-2848814|uniprotkb:A8JZZ6|uniprotkb:Q9BT71|ensembl:ENSP00000380793	psi-mi:srpx_human(display_long)|uniprotkb:SRPX(gene name)|psi-mi:SRPX(display_short)|uniprotkb:ETX1(gene name synonym)	psi-mi:alg3_human(display_long)|uniprotkb:ALG3(gene name)|psi-mi:ALG3(display_short)|uniprotkb:Asparagine-linked glycosylation protein 3 homolog(gene name synonym)|uniprotkb:"Dol-P-Man-dependent alpha(1-3)-mannosyltransferase"(gene name synonym)|uniprotkb:"Dolichyl-P-Man:Man(5)GlcNAc(2)-PP-dolichyl mannosyltransferase"(gene name synonym)|uniprotkb:Dolichyl-phosphate-mannose--glycolipid alpha-mannosyltransferase(gene name synonym)|uniprotkb:NOT(gene name synonym)|uniprotkb:NOT56L(gene name synonym)|uniprotkb:Not56-like protein(gene name synonym)	psi-mi:"MI:0018"(two hybrid)	Hacker et al. (2018)	imex:IM-28062|pubmed:29547901	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0486"(UniProt)	intact:EBI-25468391|imex:IM-28062-3	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001164221.1|refseq:NP_006298.1|refseq:NP_001164222.1|refseq:NP_001164223.1|ensembl:ENSG00000101955(gene)|ensembl:ENST00000378533(transcript)|go:"GO:0001845"(phagolysosome assembly)|go:"GO:0005776"(autophagosome)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0006914"(autophagy)|go:"GO:0007155"(cell adhesion)|go:"GO:0009986"(cell surface)|go:"GO:0016020"(membrane)|go:"GO:0034976"(response to endoplasmic reticulum stress)|go:"GO:0060244"(negative regulation of cell proliferation involved in contact inhibition)|go:"GO:0062023"(collagen-containing extracellular matrix)|go:"GO:2001241"(positive regulation of extrinsic apoptotic signaling pathway in absence of ligand)|interpro:IPR000436(Sushi/SCR/CCP)|interpro:IPR003410(Hyalin)|interpro:IPR025232|interpro:IPR035976|interpro:IPR036981|interpro:IPR043555	refseq:NP_005778.1|refseq:NP_001006942.1|ensembl:ENSG00000214160(gene)|ensembl:ENST00000397676(transcript)|go:"GO:0000033"(alpha-1,3-mannosyltransferase activity)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006486"(protein glycosylation)|go:"GO:0006488"(dolichol-linked oligosaccharide biosynthetic process)|go:"GO:0016021"(integral component of membrane)|go:"GO:0052925"("dol-P-Man:Man(5)GlcNAc(2)-PP-Dol alpha-1,3-mannosyltransferase activity")|interpro:IPR007873(ALG3)|reactome:R-HSA-446193|reactome:R-HSA-4720475	-	-	-	figure legend:Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2020/03/10	2020/03/11	rogid:xMO7Kxy17NsHmML5HETICRb8ba09606	rogid:/aBCE7QqVCyHZDzq3oSoqtiDlBI9606	rigid:jXgsfW7Xo/q+G7jnyiplPrLW6Ic	false	sufficient binding region:1-82	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q14318	uniprotkb:Q92685	intact:EBI-724839|uniprotkb:Q53GU3|uniprotkb:Q7Z349|uniprotkb:Q86YK6|ensembl:ENSP00000222308|ensembl:ENSP00000472302|uniprotkb:C8C9T5	intact:EBI-2848814|uniprotkb:A8JZZ6|uniprotkb:Q9BT71|ensembl:ENSP00000380793	psi-mi:fkbp8_human(display_long)|uniprotkb:FK506-binding protein 8(gene name synonym)|uniprotkb:38 kDa FK506-binding protein(gene name synonym)|uniprotkb:FKBPR38(gene name synonym)|uniprotkb:FKBP8(gene name)|psi-mi:FKBP8(display_short)|uniprotkb:FKBP38(gene name synonym)|uniprotkb:Rotamase(gene name synonym)	psi-mi:alg3_human(display_long)|uniprotkb:ALG3(gene name)|psi-mi:ALG3(display_short)|uniprotkb:Asparagine-linked glycosylation protein 3 homolog(gene name synonym)|uniprotkb:"Dol-P-Man-dependent alpha(1-3)-mannosyltransferase"(gene name synonym)|uniprotkb:"Dolichyl-P-Man:Man(5)GlcNAc(2)-PP-dolichyl mannosyltransferase"(gene name synonym)|uniprotkb:Dolichyl-phosphate-mannose--glycolipid alpha-mannosyltransferase(gene name synonym)|uniprotkb:NOT(gene name synonym)|uniprotkb:NOT56L(gene name synonym)|uniprotkb:Not56-like protein(gene name synonym)	psi-mi:"MI:0018"(two hybrid)	Hacker et al. (2018)	imex:IM-28062|pubmed:29547901	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0486"(UniProt)	intact:EBI-25468397|imex:IM-28062-5	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_036313.3|refseq:NP_001295302.1|go:"GO:0001708"(cell fate specification)|go:"GO:0001933"(negative regulation of protein phosphorylation)|go:"GO:0003755"(peptidyl-prolyl cis-trans isomerase activity)|go:"GO:0005739"(mitochondrion)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005829"(cytosol)|go:"GO:0006457"(protein folding)|go:"GO:0006915"(apoptotic process)|go:"GO:0007224"(smoothened signaling pathway)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0016020"(membrane)|go:"GO:0021904"(dorsal/ventral neural tube patterning)|go:"GO:0030176"(integral component of endoplasmic reticulum membrane)|go:"GO:0030513"(positive regulation of BMP signaling pathway)|go:"GO:0031966"(mitochondrial membrane)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035264"(multicellular organism growth)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0042802"(identical protein binding)|go:"GO:0043010"(camera-type eye development)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0044183"(protein folding chaperone)|go:"GO:0046872"(metal ion binding)|go:"GO:0097718"(disordered domain specific binding)|interpro:IPR001179(Peptidyl-prolyl cis-trans isomerase, FKBP-type)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR013105(Tetratricopeptide TPR2)|interpro:IPR019734|mint:Q14318|ensembl:ENSG00000105701(gene)|rcsb pdb:2AWG|rcsb pdb:2D9F|rcsb pdb:2F2D|rcsb pdb:2MF9|rcsb pdb:3EY6|rcsb pdb:5MGX|reactome:R-HSA-5689880|ensembl:ENST00000222308(transcript)|ensembl:ENST00000596558(transcript)|refseq:XP_011526165.1|dip:DIP-42200N	refseq:NP_005778.1|refseq:NP_001006942.1|ensembl:ENSG00000214160(gene)|ensembl:ENST00000397676(transcript)|go:"GO:0000033"(alpha-1,3-mannosyltransferase activity)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006486"(protein glycosylation)|go:"GO:0006488"(dolichol-linked oligosaccharide biosynthetic process)|go:"GO:0016021"(integral component of membrane)|go:"GO:0052925"("dol-P-Man:Man(5)GlcNAc(2)-PP-Dol alpha-1,3-mannosyltransferase activity")|interpro:IPR007873(ALG3)|reactome:R-HSA-446193|reactome:R-HSA-4720475	-	-	-	figure legend:Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2020/03/10	2020/03/11	rogid:CpZqwry5szPluwNMwWXshCIMUvY9606	rogid:/aBCE7QqVCyHZDzq3oSoqtiDlBI9606	rigid:5RdxMYiV0g3Kor36Kyrg6jKgfpg	false	sufficient binding region:1-250	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P32455	uniprotkb:Q92685	intact:EBI-2869161|uniprotkb:Q5T8M1|uniprotkb:D3DT26|ensembl:ENSP00000359504	intact:EBI-2848814|uniprotkb:A8JZZ6|uniprotkb:Q9BT71|ensembl:ENSP00000380793	psi-mi:gbp1_human(display_long)|uniprotkb:GBP1(gene name)|psi-mi:GBP1(display_short)|uniprotkb:GTP-binding protein 1(gene name synonym)|uniprotkb:Guanine nucleotide-binding protein 1(gene name synonym)|uniprotkb:Interferon-induced guanylate-binding protein 1(gene name synonym)	psi-mi:alg3_human(display_long)|uniprotkb:ALG3(gene name)|psi-mi:ALG3(display_short)|uniprotkb:Asparagine-linked glycosylation protein 3 homolog(gene name synonym)|uniprotkb:"Dol-P-Man-dependent alpha(1-3)-mannosyltransferase"(gene name synonym)|uniprotkb:"Dolichyl-P-Man:Man(5)GlcNAc(2)-PP-dolichyl mannosyltransferase"(gene name synonym)|uniprotkb:Dolichyl-phosphate-mannose--glycolipid alpha-mannosyltransferase(gene name synonym)|uniprotkb:NOT(gene name synonym)|uniprotkb:NOT56L(gene name synonym)|uniprotkb:Not56-like protein(gene name synonym)	psi-mi:"MI:0018"(two hybrid)	Hacker et al. (2018)	imex:IM-28062|pubmed:29547901	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0486"(UniProt)	intact:EBI-25468405|imex:IM-28062-25	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_002044.2|dip:DIP-60423N|go:"GO:0003779"(actin binding)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005576"(extracellular region)|ensembl:ENSG00000117228(gene)|ensembl:ENST00000370473(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0012506"(vesicle membrane)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0019003"(GDP binding)|go:"GO:0019899"(enzyme binding)|go:"GO:0019955"(cytokine binding)|go:"GO:0030507"(spectrin binding)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0032703"(negative regulation of interleukin-2 production)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0050848"(regulation of calcium-mediated signaling)|go:"GO:0050860"(negative regulation of T cell receptor signaling pathway)|go:"GO:0051607"(defense response to virus)|go:"GO:0051879"(Hsp90 protein binding)|go:"GO:0070373"(negative regulation of ERK1 and ERK2 cascade)|go:"GO:0071346"(cellular response to interferon-gamma)|go:"GO:0071347"(cellular response to interleukin-1)|go:"GO:0005737"(cytoplasm)|go:"GO:0072665"(protein localization to vacuole)|go:"GO:1900025"(negative regulation of substrate adhesion-dependent cell spreading)|go:"GO:1903076"(regulation of protein localization to plasma membrane)|go:"GO:1903077"(negative regulation of protein localization to plasma membrane)|interpro:IPR003191(Guanylate-binding protein, C-terminal)|interpro:IPR015894(Guanylate-binding protein, N-terminal)|interpro:IPR027417|interpro:IPR030386|interpro:IPR036543|interpro:IPR037684|rcsb pdb:1DG3|rcsb pdb:1F5N|rcsb pdb:2B8W|rcsb pdb:2B92|rcsb pdb:2BC9|rcsb pdb:2D4H|rcsb pdb:6K1Z|rcsb pdb:6K2D|rcsb pdb:6LOJ|reactome:R-HSA-877300|go:"GO:0071356"(cellular response to tumor necrosis factor)	refseq:NP_005778.1|refseq:NP_001006942.1|ensembl:ENSG00000214160(gene)|ensembl:ENST00000397676(transcript)|go:"GO:0000033"(alpha-1,3-mannosyltransferase activity)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006486"(protein glycosylation)|go:"GO:0006488"(dolichol-linked oligosaccharide biosynthetic process)|go:"GO:0016021"(integral component of membrane)|go:"GO:0052925"("dol-P-Man:Man(5)GlcNAc(2)-PP-Dol alpha-1,3-mannosyltransferase activity")|interpro:IPR007873(ALG3)|reactome:R-HSA-446193|reactome:R-HSA-4720475	-	-	-	figure legend:Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2020/03/10	2020/03/11	rogid:Qjj2KnkVnK0/Er0/5prkVVL6OxY9606	rogid:/aBCE7QqVCyHZDzq3oSoqtiDlBI9606	rigid:wS1Zn6ARyMwQmX8lIMTdIAh6vBU	false	sufficient binding region:449-592	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P30519	uniprotkb:Q92685	intact:EBI-712096|uniprotkb:I3L430|ensembl:ENSP00000219700|ensembl:ENSP00000381595|ensembl:ENSP00000385100|ensembl:ENSP00000391637|ensembl:ENSP00000394103|ensembl:ENSP00000459214|ensembl:ENSP00000478785|ensembl:ENSP00000481295|ensembl:ENSP00000481811|ensembl:ENSP00000483319|ensembl:ENSP00000484422|ensembl:ENSP00000484423|ensembl:ENSP00000484467|ensembl:ENSP00000487673|ensembl:ENSP00000488579|ensembl:ENSP00000488880|uniprotkb:O60605|uniprotkb:A8MT35|uniprotkb:D3DUD5	intact:EBI-2848814|uniprotkb:A8JZZ6|uniprotkb:Q9BT71|ensembl:ENSP00000380793	psi-mi:hmox2_human(display_long)|uniprotkb:HMOX2(gene name)|psi-mi:HMOX2(display_short)|uniprotkb:HO2(gene name synonym)	psi-mi:alg3_human(display_long)|uniprotkb:ALG3(gene name)|psi-mi:ALG3(display_short)|uniprotkb:Asparagine-linked glycosylation protein 3 homolog(gene name synonym)|uniprotkb:"Dol-P-Man-dependent alpha(1-3)-mannosyltransferase"(gene name synonym)|uniprotkb:"Dolichyl-P-Man:Man(5)GlcNAc(2)-PP-dolichyl mannosyltransferase"(gene name synonym)|uniprotkb:Dolichyl-phosphate-mannose--glycolipid alpha-mannosyltransferase(gene name synonym)|uniprotkb:NOT(gene name synonym)|uniprotkb:NOT56L(gene name synonym)|uniprotkb:Not56-like protein(gene name synonym)	psi-mi:"MI:0018"(two hybrid)	Hacker et al. (2018)	imex:IM-28062|pubmed:29547901	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0486"(UniProt)	intact:EBI-25468412|imex:IM-28062-7	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001273196.1|refseq:NP_001273197.1|refseq:NP_001273198.1|refseq:NP_001273199.1|refseq:NP_001273200.1|ensembl:ENSG00000103415(gene)|ensembl:ENSG00000277424(gene)|ensembl:ENST00000219700(transcript)|ensembl:ENST00000398595(transcript)|ensembl:ENST00000406590(transcript)|ensembl:ENST00000414777(transcript)|ensembl:ENST00000458134(transcript)|ensembl:ENST00000570646(transcript)|ensembl:ENST00000612525(transcript)|ensembl:ENST00000615778(transcript)|ensembl:ENST00000619528(transcript)|ensembl:ENST00000619913(transcript)|ensembl:ENST00000620445(transcript)|ensembl:ENST00000621065(transcript)|ensembl:ENST00000622146(transcript)|ensembl:ENST00000631540(transcript)|ensembl:ENST00000631677(transcript)|ensembl:ENST00000632458(transcript)|go:"GO:0001666"(response to hypoxia)|go:"GO:0004392"("heme oxygenase (decyclizing) activity")|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005886"(plasma membrane)|go:"GO:0006788"(heme oxidation)|go:"GO:0006979"(response to oxidative stress)|go:"GO:0016020"(membrane)|go:"GO:0020037"(heme binding)|go:"GO:0035579"(specific granule membrane)|go:"GO:0042167"(heme catabolic process)|go:"GO:0046872"(metal ion binding)|go:"GO:0055072"(iron ion homeostasis)|interpro:IPR002051(Haem oxygenase)|interpro:IPR016053(Haem oxygenase-like)|interpro:IPR016084(Haem oxygenase-like, multi-helical)|interpro:IPR018207|rcsb pdb:4WMH|rcsb pdb:5UC8|rcsb pdb:5UC9|rcsb pdb:5UCA|reactome:R-HSA-189483|reactome:R-HSA-6798695|reactome:R-HSA-8980692|reactome:R-HSA-917937|reactome:R-HSA-9707564|mint:P30519|rcsb pdb:2Q32|rcsb pdb:2QPP|rcsb pdb:2RGZ|refseq:NP_001120676.1|refseq:NP_001120677.1|refseq:NP_001120678.1|refseq:NP_002125.3|refseq:XP_016878685.1|refseq:XP_016878686.1|dip:DIP-53564N	refseq:NP_005778.1|refseq:NP_001006942.1|ensembl:ENSG00000214160(gene)|ensembl:ENST00000397676(transcript)|go:"GO:0000033"(alpha-1,3-mannosyltransferase activity)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006486"(protein glycosylation)|go:"GO:0006488"(dolichol-linked oligosaccharide biosynthetic process)|go:"GO:0016021"(integral component of membrane)|go:"GO:0052925"("dol-P-Man:Man(5)GlcNAc(2)-PP-Dol alpha-1,3-mannosyltransferase activity")|interpro:IPR007873(ALG3)|reactome:R-HSA-446193|reactome:R-HSA-4720475	-	-	-	figure legend:Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2020/03/10	2020/03/11	rogid:yTwXdEjnQgfiFBvl5fhcCwDOJWo9606	rogid:/aBCE7QqVCyHZDzq3oSoqtiDlBI9606	rigid:p6iCLju5A6W2Zl1Z0FeuOhd5k2E	false	sufficient binding region:1-226	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q12983	uniprotkb:Q92685	intact:EBI-749464|uniprotkb:O14620|uniprotkb:Q96GP0|intact:EBI-28978130|ensembl:ENSP00000357625	intact:EBI-2848814|uniprotkb:A8JZZ6|uniprotkb:Q9BT71|ensembl:ENSP00000380793	psi-mi:bnip3_human(display_long)|uniprotkb:BNIP3(gene name)|psi-mi:BNIP3(display_short)|uniprotkb:NIP3(gene name synonym)	psi-mi:alg3_human(display_long)|uniprotkb:ALG3(gene name)|psi-mi:ALG3(display_short)|uniprotkb:Asparagine-linked glycosylation protein 3 homolog(gene name synonym)|uniprotkb:"Dol-P-Man-dependent alpha(1-3)-mannosyltransferase"(gene name synonym)|uniprotkb:"Dolichyl-P-Man:Man(5)GlcNAc(2)-PP-dolichyl mannosyltransferase"(gene name synonym)|uniprotkb:Dolichyl-phosphate-mannose--glycolipid alpha-mannosyltransferase(gene name synonym)|uniprotkb:NOT(gene name synonym)|uniprotkb:NOT56L(gene name synonym)|uniprotkb:Not56-like protein(gene name synonym)	psi-mi:"MI:0018"(two hybrid)	Hacker et al. (2018)	imex:IM-28062|pubmed:29547901	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0486"(UniProt)	intact:EBI-25468418|imex:IM-28062-27	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSP00000357625|refseq:NP_004043.3|dip:DIP-34429N|ensembl:ENSG00000176171(gene)|ensembl:ENST00000368636(transcript)|go:"GO:0000422"(autophagy of mitochondrion)|go:"GO:0001666"(response to hypoxia)|go:"GO:0005634"(nucleus)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0006915"(apoptotic process)|go:"GO:0008219"(cell death)|go:"GO:0009617"(response to bacterium)|go:"GO:0010508"(positive regulation of autophagy)|go:"GO:0010637"(negative regulation of mitochondrial fusion)|go:"GO:0010659"(cardiac muscle cell apoptotic process)|go:"GO:0010666"(positive regulation of cardiac muscle cell apoptotic process)|go:"GO:0010917"(negative regulation of mitochondrial membrane potential)|go:"GO:0010940"(positive regulation of necrotic cell death)|go:"GO:0014069"(postsynaptic density)|go:"GO:0016239"(positive regulation of macroautophagy)|go:"GO:0021987"(cerebral cortex development)|go:"GO:0030425"(dendrite)|go:"GO:0031307"(integral component of mitochondrial outer membrane)|go:"GO:0031966"(mitochondrial membrane)|go:"GO:0035694"(mitochondrial protein catabolic process)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043067"(regulation of programmed cell death)|go:"GO:0043068"(positive regulation of programmed cell death)|go:"GO:0043243"(positive regulation of protein-containing complex disassembly)|go:"GO:0043653"(mitochondrial fragmentation involved in apoptotic process)|go:"GO:0045837"(negative regulation of membrane potential)|go:"GO:0046902"(regulation of mitochondrial membrane permeability)|go:"GO:0048102"(autophagic cell death)|go:"GO:0048678"(response to axon injury)|go:"GO:0048709"(oligodendrocyte differentiation)|go:"GO:0050873"(brown fat cell differentiation)|go:"GO:0051020"(GTPase binding)|go:"GO:0051402"(neuron apoptotic process)|go:"GO:0051561"(positive regulation of mitochondrial calcium ion concentration)|go:"GO:0051607"(defense response to virus)|go:"GO:0055093"(response to hyperoxia)|go:"GO:0060548"(negative regulation of cell death)|go:"GO:0070301"(cellular response to hydrogen peroxide)|go:"GO:0071260"(cellular response to mechanical stimulus)|go:"GO:0071279"(cellular response to cobalt ion)|go:"GO:0071456"(cellular response to hypoxia)|go:"GO:0072593"(reactive oxygen species metabolic process)|go:"GO:0090141"(positive regulation of mitochondrial fission)|go:"GO:0090200"(positive regulation of release of cytochrome c from mitochondria)|go:"GO:0090649"(response to oxygen-glucose deprivation)|go:"GO:0097345"(mitochondrial outer membrane permeabilization)|go:"GO:0140507"(granzyme-mediated programmed cell death signaling pathway)|go:"GO:1901998"(toxin transport)|go:"GO:1902109"(negative regulation of mitochondrial membrane permeability involved in apoptotic process)|go:"GO:1903599"(positive regulation of autophagy of mitochondrion)|go:"GO:1903715"(regulation of aerobic respiration)|go:"GO:1990144"(intrinsic apoptotic signaling pathway in response to hypoxia)|go:"GO:2000378"(negative regulation of reactive oxygen species metabolic process)|interpro:IPR010548(BNIP3)|mint:Q12983|rcsb pdb:2J5D|rcsb pdb:2KA1|rcsb pdb:2KA2	refseq:NP_005778.1|refseq:NP_001006942.1|ensembl:ENSG00000214160(gene)|ensembl:ENST00000397676(transcript)|go:"GO:0000033"(alpha-1,3-mannosyltransferase activity)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006486"(protein glycosylation)|go:"GO:0006488"(dolichol-linked oligosaccharide biosynthetic process)|go:"GO:0016021"(integral component of membrane)|go:"GO:0052925"("dol-P-Man:Man(5)GlcNAc(2)-PP-Dol alpha-1,3-mannosyltransferase activity")|interpro:IPR007873(ALG3)|reactome:R-HSA-446193|reactome:R-HSA-4720475	-	crc64:53967696EDA005E2	-	figure legend:Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2020/03/10	2020/03/11	rogid:f+opYD7xO+AbYqLXXC5wh4ZJqIE9606	rogid:/aBCE7QqVCyHZDzq3oSoqtiDlBI9606	rigid:IZ8pBBVCnANJXbo0zXGrj10lnoQ	false	sufficient binding region:1-126	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P22059	uniprotkb:Q92685	intact:EBI-2681902|uniprotkb:Q6P524|ensembl:ENSP00000263847	intact:EBI-2848814|uniprotkb:A8JZZ6|uniprotkb:Q9BT71|ensembl:ENSP00000380793	psi-mi:osbp1_human(display_long)|uniprotkb:OSBP1(gene name synonym)|uniprotkb:OSBP(gene name)|psi-mi:OSBP(display_short)	psi-mi:alg3_human(display_long)|uniprotkb:ALG3(gene name)|psi-mi:ALG3(display_short)|uniprotkb:Asparagine-linked glycosylation protein 3 homolog(gene name synonym)|uniprotkb:"Dol-P-Man-dependent alpha(1-3)-mannosyltransferase"(gene name synonym)|uniprotkb:"Dolichyl-P-Man:Man(5)GlcNAc(2)-PP-dolichyl mannosyltransferase"(gene name synonym)|uniprotkb:Dolichyl-phosphate-mannose--glycolipid alpha-mannosyltransferase(gene name synonym)|uniprotkb:NOT(gene name synonym)|uniprotkb:NOT56L(gene name synonym)|uniprotkb:Not56-like protein(gene name synonym)	psi-mi:"MI:0018"(two hybrid)	Hacker et al. (2018)	imex:IM-28062|pubmed:29547901	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0486"(UniProt)	intact:EBI-25468424|imex:IM-28062-29	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_002547.1|ensembl:ENSG00000110048(gene)|ensembl:ENST00000263847(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006699"(bile acid biosynthetic process)|go:"GO:0008142"(oxysterol binding)|go:"GO:0015248"(sterol transporter activity)|go:"GO:0015918"(sterol transport)|go:"GO:0016020"(membrane)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030054"(cell junction)|go:"GO:0032367"(intracellular cholesterol transport)|go:"GO:0032934"(sterol binding)|go:"GO:0035774"(positive regulation of insulin secretion involved in cellular response to glucose stimulus)|go:"GO:0042531"(positive regulation of tyrosine phosphorylation of STAT protein)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0070273"(phosphatidylinositol-4-phosphate binding)|go:"GO:0097038"(perinuclear endoplasmic reticulum)|go:"GO:0120015"(sterol transfer activity)|go:"GO:1904411"(positive regulation of secretory granule organization)|interpro:IPR000648(Oxysterol-binding protein)|interpro:IPR018494|interpro:IPR037239|rcsb pdb:2RR3|reactome:R-HSA-1660661|reactome:R-HSA-192105|interpro:IPR001849(Pleckstrin-like)|interpro:IPR011993(Pleckstrin homology-type)	refseq:NP_005778.1|refseq:NP_001006942.1|ensembl:ENSG00000214160(gene)|ensembl:ENST00000397676(transcript)|go:"GO:0000033"(alpha-1,3-mannosyltransferase activity)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006486"(protein glycosylation)|go:"GO:0006488"(dolichol-linked oligosaccharide biosynthetic process)|go:"GO:0016021"(integral component of membrane)|go:"GO:0052925"("dol-P-Man:Man(5)GlcNAc(2)-PP-Dol alpha-1,3-mannosyltransferase activity")|interpro:IPR007873(ALG3)|reactome:R-HSA-446193|reactome:R-HSA-4720475	-	-	-	figure legend:Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2020/03/10	2020/03/11	rogid:9LgzhfWQ0E/ECTTKA1OogQSyuAI9606	rogid:/aBCE7QqVCyHZDzq3oSoqtiDlBI9606	rigid:N5y+7Zmh0cnZNCx5AvGfXR+ToW4	false	sufficient binding region:195-474	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q96SU4	uniprotkb:Q92685	intact:EBI-2511368|ensembl:ENSP00000407168|uniprotkb:Q6IA67|uniprotkb:Q9H9X2|uniprotkb:Q96SK4|uniprotkb:B1AKJ8|uniprotkb:Q5TFC0|uniprotkb:Q8NB17|uniprotkb:Q8TAS8|uniprotkb:D3DQ31|uniprotkb:B3KPQ4|uniprotkb:Q86YQ3	intact:EBI-2848814|uniprotkb:A8JZZ6|uniprotkb:Q9BT71|ensembl:ENSP00000380793	psi-mi:osbl9_human(display_long)|uniprotkb:OSBPL9(gene name)|psi-mi:OSBPL9(display_short)|uniprotkb:ORP9(gene name synonym)|uniprotkb:OSBP4(gene name synonym)	psi-mi:alg3_human(display_long)|uniprotkb:ALG3(gene name)|psi-mi:ALG3(display_short)|uniprotkb:Asparagine-linked glycosylation protein 3 homolog(gene name synonym)|uniprotkb:"Dol-P-Man-dependent alpha(1-3)-mannosyltransferase"(gene name synonym)|uniprotkb:"Dolichyl-P-Man:Man(5)GlcNAc(2)-PP-dolichyl mannosyltransferase"(gene name synonym)|uniprotkb:Dolichyl-phosphate-mannose--glycolipid alpha-mannosyltransferase(gene name synonym)|uniprotkb:NOT(gene name synonym)|uniprotkb:NOT56L(gene name synonym)|uniprotkb:Not56-like protein(gene name synonym)	psi-mi:"MI:0018"(two hybrid)	Hacker et al. (2018)	imex:IM-28062|pubmed:29547901	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0486"(UniProt)	intact:EBI-25468430|imex:IM-28062-31	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000117859(gene)|ensembl:ENST00000428468(transcript)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0006699"(bile acid biosynthetic process)|go:"GO:0015248"(sterol transporter activity)|go:"GO:0016020"(membrane)|go:"GO:0031902"(late endosome membrane)|go:"GO:0032934"(sterol binding)|go:"GO:0043231"(intracellular membrane-bounded organelle)|interpro:IPR000648(Oxysterol-binding protein)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR018494|interpro:IPR037239|mint:Q96SU4|reactome:R-HSA-192105|refseq:XP_011538905.1|refseq:XP_011538906.1|refseq:NP_078862.4|refseq:NP_683702.1|refseq:NP_683703.1|refseq:NP_683705.1|refseq:NP_683706.3|refseq:NP_683704.2|refseq:NP_683707.3|refseq:XP_006710386.1|refseq:XP_006710387.1|refseq:XP_006710388.1|refseq:XP_006710389.1|refseq:NP_001317509.1|refseq:XP_016855708.1|refseq:XP_016855709.1|refseq:XP_016855710.1	refseq:NP_005778.1|refseq:NP_001006942.1|ensembl:ENSG00000214160(gene)|ensembl:ENST00000397676(transcript)|go:"GO:0000033"(alpha-1,3-mannosyltransferase activity)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006486"(protein glycosylation)|go:"GO:0006488"(dolichol-linked oligosaccharide biosynthetic process)|go:"GO:0016021"(integral component of membrane)|go:"GO:0052925"("dol-P-Man:Man(5)GlcNAc(2)-PP-Dol alpha-1,3-mannosyltransferase activity")|interpro:IPR007873(ALG3)|reactome:R-HSA-446193|reactome:R-HSA-4720475	-	-	-	figure legend:Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2020/03/10	2020/03/11	rogid:2XLQ0JD4BEKGoyiwd/63YTmyVlE9606	rogid:/aBCE7QqVCyHZDzq3oSoqtiDlBI9606	rigid:ofv4GAB2DoCGlNyOFfcMNOcnEoM	false	sufficient binding region:72-327	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P04233	uniprotkb:Q92685	intact:EBI-2622890|uniprotkb:D3DQG3|uniprotkb:D3DQG4|uniprotkb:A8K7R1|uniprotkb:B4DNE8|uniprotkb:Q29832|uniprotkb:Q14597|uniprotkb:Q8SNA0|uniprotkb:Q8WLP6|uniprotkb:Q5U0J8|ensembl:ENSP00000009530	intact:EBI-2848814|uniprotkb:A8JZZ6|uniprotkb:Q9BT71|ensembl:ENSP00000380793	psi-mi:hg2a_human(display_long)|uniprotkb:DHLAG(gene name synonym)|uniprotkb:HLA-DR antigens-associated invariant chain(gene name synonym)|uniprotkb:Ia antigen-associated invariant chain(gene name synonym)|uniprotkb:CD74(gene name)|psi-mi:CD74(display_short)	psi-mi:alg3_human(display_long)|uniprotkb:ALG3(gene name)|psi-mi:ALG3(display_short)|uniprotkb:Asparagine-linked glycosylation protein 3 homolog(gene name synonym)|uniprotkb:"Dol-P-Man-dependent alpha(1-3)-mannosyltransferase"(gene name synonym)|uniprotkb:"Dolichyl-P-Man:Man(5)GlcNAc(2)-PP-dolichyl mannosyltransferase"(gene name synonym)|uniprotkb:Dolichyl-phosphate-mannose--glycolipid alpha-mannosyltransferase(gene name synonym)|uniprotkb:NOT(gene name synonym)|uniprotkb:NOT56L(gene name synonym)|uniprotkb:Not56-like protein(gene name synonym)	psi-mi:"MI:0018"(two hybrid)	Hacker et al. (2018)	imex:IM-28062|pubmed:29547901	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0486"(UniProt)	intact:EBI-25468436|imex:IM-28062-41	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001020329.1|refseq:NP_001020330.1|refseq:NP_004346.1|ensembl:ENSG00000019582(gene)|ensembl:ENST00000009530(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0000187"(obsolete activation of MAPK activity)|go:"GO:0001516"(prostaglandin biosynthetic process)|go:"GO:0001540"(amyloid-beta binding)|go:"GO:0001934"(positive regulation of protein phosphorylation)|go:"GO:0001961"(positive regulation of cytokine-mediated signaling pathway)|go:"GO:0002286"(T cell activation involved in immune response)|go:"GO:0002606"(positive regulation of dendritic cell antigen processing and presentation)|go:"GO:0002792"(negative regulation of peptide secretion)|go:"GO:0002830"(positive regulation of type 2 immune response)|go:"GO:0002906"(negative regulation of mature B cell apoptotic process)|go:"GO:0004896"(cytokine receptor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005764"(lysosome)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005770"(late endosome)|go:"GO:0005771"(multivesicular body)|go:"GO:0005773"(vacuole)|go:"GO:0005886"(plasma membrane)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0008283"(cell population proliferation)|go:"GO:0009986"(cell surface)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0012507"(ER to Golgi transport vesicle membrane)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016064"(immunoglobulin mediated immune response)|go:"GO:0019882"(antigen processing and presentation)|go:"GO:0009897"(external side of plasma membrane)|go:"GO:0019883"(antigen processing and presentation of endogenous antigen)|go:"GO:0019886"(antigen processing and presentation of exogenous peptide antigen via MHC class II)|go:"GO:0019955"(cytokine binding)|go:"GO:0023026"(MHC class II protein complex binding)|go:"GO:0030336"(negative regulation of cell migration)|go:"GO:0030658"(transport vesicle membrane)|go:"GO:0030666"(endocytic vesicle membrane)|go:"GO:0030669"(clathrin-coated endocytic vesicle membrane)|go:"GO:0030890"(positive regulation of B cell proliferation)|go:"GO:0031394"(positive regulation of prostaglandin biosynthetic process)|go:"GO:0032588"(trans-Golgi network membrane)|go:"GO:0032722"(positive regulation of chemokine production)|go:"GO:0032755"(positive regulation of interleukin-6 production)|go:"GO:0032757"(positive regulation of interleukin-8 production)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033674"(positive regulation of kinase activity)|go:"GO:0034341"(response to interferon-gamma)|go:"GO:0035691"(macrophage migration inhibitory factor signaling pathway)|go:"GO:0035692"(macrophage migration inhibitory factor receptor complex)|go:"GO:0035693"(NOS2-CD74 complex)|go:"GO:0035718"(macrophage migration inhibitory factor binding)|go:"GO:0042289"(MHC class II protein binding)|go:"GO:0042609"(CD4 receptor binding)|go:"GO:0042613"(MHC class II protein complex)|go:"GO:0042658"(MHC class II protein binding, via antigen binding groove)|go:"GO:0042802"(identical protein binding)|go:"GO:0043030"(regulation of macrophage activation)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043202"(lysosomal lumen)|go:"GO:0043410"(positive regulation of MAPK cascade)|go:"GO:0043518"(negative regulation of DNA damage response, signal transduction by p53 class mediator)|go:"GO:0044183"(protein folding chaperone)|go:"GO:0045058"(T cell selection)|go:"GO:0045059"(positive thymic T cell selection)|go:"GO:0045060"(negative thymic T cell selection)|go:"GO:0045581"(negative regulation of T cell differentiation)|go:"GO:0045582"(positive regulation of T cell differentiation)|go:"GO:0045657"(positive regulation of monocyte differentiation)|go:"GO:0071556"(integral component of lumenal side of endoplasmic reticulum membrane)|go:"GO:0090023"(positive regulation of neutrophil chemotaxis)|go:"GO:1902166"(negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator)|go:"GO:2000343"("positive regulation of chemokine (C-X-C motif) ligand 2 production")|go:"GO:2000448"(positive regulation of macrophage migration inhibitory factor signaling pathway)|interpro:IPR000716(Thyroglobulin type-1)|interpro:IPR011988(MHC class II-associated invariant chain, trimerisation)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|interpro:IPR015386(MHC class II-associated invariant chain/CLIP, MHC II-interacting)|interpro:IPR022339|interpro:IPR036613|go:"GO:0046597"(negative regulation of viral entry into host cell)|interpro:IPR036857|interpro:IPR043530|mint:P04233|rcsb pdb:1A6A|rcsb pdb:1ICF|rcsb pdb:1IIE|rcsb pdb:1L3H|rcsb pdb:1MUJ|rcsb pdb:3PDO|rcsb pdb:3PGC|rcsb pdb:3PGD|go:"GO:0046598"(positive regulation of viral entry into host cell)|rcsb pdb:3QXA|go:"GO:0048146"(positive regulation of fibroblast proliferation)|rcsb pdb:3QXD|rcsb pdb:4AEN|rcsb pdb:4AH2|rcsb pdb:4X5W|go:"GO:0050731"(positive regulation of peptidyl-tyrosine phosphorylation)|rcsb pdb:5KSU|rcsb pdb:5KSV|go:"GO:0050821"(protein stabilization)|reactome:R-HSA-202733|reactome:R-HSA-2132295|go:"GO:0050998"(nitric-oxide synthase binding)|go:"GO:0051085"(chaperone cofactor-dependent protein refolding)|go:"GO:0060907"(positive regulation of macrophage cytokine production)|go:"GO:0065003"(protein-containing complex assembly)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070206"(protein trimerization)|go:"GO:0070374"(positive regulation of ERK1 and ERK2 cascade)	refseq:NP_005778.1|refseq:NP_001006942.1|ensembl:ENSG00000214160(gene)|ensembl:ENST00000397676(transcript)|go:"GO:0000033"(alpha-1,3-mannosyltransferase activity)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006486"(protein glycosylation)|go:"GO:0006488"(dolichol-linked oligosaccharide biosynthetic process)|go:"GO:0016021"(integral component of membrane)|go:"GO:0052925"("dol-P-Man:Man(5)GlcNAc(2)-PP-Dol alpha-1,3-mannosyltransferase activity")|interpro:IPR007873(ALG3)|reactome:R-HSA-446193|reactome:R-HSA-4720475	-	-	-	figure legend:Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2020/03/10	2020/03/11	rogid:jP1UH09kpXY45O7Qr5OdAfDDIXY9606	rogid:/aBCE7QqVCyHZDzq3oSoqtiDlBI9606	rigid:Y97yeADm67hGTQO8NbCQnxJ/Mgc	false	sufficient binding region:10-232	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P53814	uniprotkb:Q92685	intact:EBI-1199956|intact:EBI-1199983|uniprotkb:Q8N4H8|uniprotkb:Q8WWW1|uniprotkb:Q8WWW2|uniprotkb:O00569|uniprotkb:O95769|uniprotkb:O95937|uniprotkb:Q9P1S8|uniprotkb:Q9UIT1|uniprotkb:Q9UIT2|ensembl:ENSP00000328635	intact:EBI-2848814|uniprotkb:A8JZZ6|uniprotkb:Q9BT71|ensembl:ENSP00000380793	psi-mi:smtn_human(display_long)|uniprotkb:SMTN(gene name)|psi-mi:SMTN(display_short)|uniprotkb:SMSMO(gene name synonym)	psi-mi:alg3_human(display_long)|uniprotkb:ALG3(gene name)|psi-mi:ALG3(display_short)|uniprotkb:Asparagine-linked glycosylation protein 3 homolog(gene name synonym)|uniprotkb:"Dol-P-Man-dependent alpha(1-3)-mannosyltransferase"(gene name synonym)|uniprotkb:"Dolichyl-P-Man:Man(5)GlcNAc(2)-PP-dolichyl mannosyltransferase"(gene name synonym)|uniprotkb:Dolichyl-phosphate-mannose--glycolipid alpha-mannosyltransferase(gene name synonym)|uniprotkb:NOT(gene name synonym)|uniprotkb:NOT56L(gene name synonym)|uniprotkb:Not56-like protein(gene name synonym)	psi-mi:"MI:0018"(two hybrid)	Hacker et al. (2018)	imex:IM-28062|pubmed:29547901	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0486"(UniProt)	intact:EBI-25468442|imex:IM-28062-9	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000183963(gene)|ensembl:ENST00000347557(transcript)|go:"GO:0003779"(actin binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005815"(microtubule organizing center)|go:"GO:0005856"(cytoskeleton)|go:"GO:0006939"(smooth muscle contraction)|go:"GO:0007517"(muscle organ development)|go:"GO:0008307"(structural constituent of muscle)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0030036"(actin cytoskeleton organization)|go:"GO:0031941"(filamentous actin)|interpro:IPR001715(Calponin-like actin-binding)|interpro:IPR022189|interpro:IPR036872|mint:P53814|rcsb pdb:2D87|refseq:NP_001193946.1|refseq:NP_001193947.1|refseq:NP_008863.3|refseq:NP_599031.1|refseq:NP_599032.2|ensembl:ENST00000333137|ensembl:ENSP00000329532|ensembl:ENSP00000328635|ensembl:ENST00000358743|ensembl:ENSP00000351593	refseq:NP_005778.1|refseq:NP_001006942.1|ensembl:ENSG00000214160(gene)|ensembl:ENST00000397676(transcript)|go:"GO:0000033"(alpha-1,3-mannosyltransferase activity)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006486"(protein glycosylation)|go:"GO:0006488"(dolichol-linked oligosaccharide biosynthetic process)|go:"GO:0016021"(integral component of membrane)|go:"GO:0052925"("dol-P-Man:Man(5)GlcNAc(2)-PP-Dol alpha-1,3-mannosyltransferase activity")|interpro:IPR007873(ALG3)|reactome:R-HSA-446193|reactome:R-HSA-4720475	-	-	-	figure legend:Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2020/03/10	2020/03/11	rogid:na+f9ZixP42TZZ0uD5P5tzaroFA9606	rogid:/aBCE7QqVCyHZDzq3oSoqtiDlBI9606	rigid:hdbde9G1hyKurWcvP4EbfNwDf00	false	sufficient binding region:25-798	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q96JE7	uniprotkb:Q92685	intact:EBI-749897|uniprotkb:Q96GX6|uniprotkb:A3EYF1|uniprotkb:Q5HYF6|uniprotkb:Q8N7D6|ensembl:ENSP00000308339	intact:EBI-2848814|uniprotkb:A8JZZ6|uniprotkb:Q9BT71|ensembl:ENSP00000380793	psi-mi:sc16b_human(display_long)|uniprotkb:KIAA1928(gene name synonym)|uniprotkb:LZTR2(gene name synonym)|uniprotkb:RGPR(gene name synonym)|uniprotkb:SEC16S(gene name synonym)|uniprotkb:SEC16 homolog B(gene name synonym)|uniprotkb:Regucalcin gene promoter region-related protein p117(gene name synonym)|uniprotkb:Leucine zipper transcription regulator 2(gene name synonym)|uniprotkb:SEC16B(gene name)|psi-mi:SEC16B(display_short)	psi-mi:alg3_human(display_long)|uniprotkb:ALG3(gene name)|psi-mi:ALG3(display_short)|uniprotkb:Asparagine-linked glycosylation protein 3 homolog(gene name synonym)|uniprotkb:"Dol-P-Man-dependent alpha(1-3)-mannosyltransferase"(gene name synonym)|uniprotkb:"Dolichyl-P-Man:Man(5)GlcNAc(2)-PP-dolichyl mannosyltransferase"(gene name synonym)|uniprotkb:Dolichyl-phosphate-mannose--glycolipid alpha-mannosyltransferase(gene name synonym)|uniprotkb:NOT(gene name synonym)|uniprotkb:NOT56L(gene name synonym)|uniprotkb:Not56-like protein(gene name synonym)	psi-mi:"MI:0018"(two hybrid)	Hacker et al. (2018)	imex:IM-28062|pubmed:29547901	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0486"(UniProt)	intact:EBI-25468448|imex:IM-28062-11	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_149118.2|go:"GO:0070863"(positive regulation of protein exit from endoplasmic reticulum)|go:"GO:0070971"(endoplasmic reticulum exit site)|go:"GO:0070973"(protein localization to endoplasmic reticulum exit site)|interpro:IPR024298|interpro:IPR024340|interpro:IPR024880|reactome:R-HSA-204005|go:"GO:0016559"(peroxisome fission)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0048208"(COPII vesicle coating)|ensembl:ENSG00000120341(gene)|ensembl:ENST00000308284(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005829"(cytosol)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0006914"(autophagy)|go:"GO:0007029"(endoplasmic reticulum organization)|go:"GO:0007030"(Golgi organization)|go:"GO:0007031"(peroxisome organization)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0012507"(ER to Golgi transport vesicle membrane)|go:"GO:0015031"(protein transport)	refseq:NP_005778.1|refseq:NP_001006942.1|ensembl:ENSG00000214160(gene)|ensembl:ENST00000397676(transcript)|go:"GO:0000033"(alpha-1,3-mannosyltransferase activity)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006486"(protein glycosylation)|go:"GO:0006488"(dolichol-linked oligosaccharide biosynthetic process)|go:"GO:0016021"(integral component of membrane)|go:"GO:0052925"("dol-P-Man:Man(5)GlcNAc(2)-PP-Dol alpha-1,3-mannosyltransferase activity")|interpro:IPR007873(ALG3)|reactome:R-HSA-446193|reactome:R-HSA-4720475	-	-	-	figure legend:Table 1|comment:Length/coordinates of SEC16B do not match any known isoform|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2020/03/10	2020/03/11	rogid:2OKkJlQi76x9/ZgR9eIA0AlEYrw9606	rogid:/aBCE7QqVCyHZDzq3oSoqtiDlBI9606	rigid:79xDnDfhW1q5n90e7S/yq5Gn67s	false	sufficient binding region:?-?	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q9UN36-2	uniprotkb:Q92685	intact:EBI-21574925|ensembl:ENSP00000344620|ensembl:ENSP00000353649|ensembl:ENSP00000452006|ensembl:ENSP00000452038|ensembl:ENSP00000452306	intact:EBI-2848814|uniprotkb:A8JZZ6|uniprotkb:Q9BT71|ensembl:ENSP00000380793	psi-mi:q9un36-2(display_long)|uniprotkb:N-myc downstream-regulated gene 2 protein(gene name synonym)|uniprotkb:Protein Syld709613(gene name synonym)|uniprotkb:NDRG2(gene name)|psi-mi:NDRG2(display_short)|uniprotkb:KIAA1248(gene name synonym)|uniprotkb:SYLD(gene name synonym)|uniprotkb:NDRG2var(isoform synonym)	psi-mi:alg3_human(display_long)|uniprotkb:ALG3(gene name)|psi-mi:ALG3(display_short)|uniprotkb:Asparagine-linked glycosylation protein 3 homolog(gene name synonym)|uniprotkb:"Dol-P-Man-dependent alpha(1-3)-mannosyltransferase"(gene name synonym)|uniprotkb:"Dolichyl-P-Man:Man(5)GlcNAc(2)-PP-dolichyl mannosyltransferase"(gene name synonym)|uniprotkb:Dolichyl-phosphate-mannose--glycolipid alpha-mannosyltransferase(gene name synonym)|uniprotkb:NOT(gene name synonym)|uniprotkb:NOT56L(gene name synonym)|uniprotkb:Not56-like protein(gene name synonym)	psi-mi:"MI:0018"(two hybrid)	Hacker et al. (2018)	imex:IM-28062|pubmed:29547901	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0486"(UniProt)	intact:EBI-25468455|imex:IM-28062-43	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000165795(gene)|ensembl:ENST00000350792(transcript)|ensembl:ENST00000360463(transcript)|ensembl:ENST00000553503(transcript)|ensembl:ENST00000554143(transcript)|ensembl:ENST00000555158(transcript)|uniprotkb:Q9UN36-2(isoform-parent)|intact:EBI-3895741(isoform-parent)	refseq:NP_005778.1|refseq:NP_001006942.1|ensembl:ENSG00000214160(gene)|ensembl:ENST00000397676(transcript)|go:"GO:0000033"(alpha-1,3-mannosyltransferase activity)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006486"(protein glycosylation)|go:"GO:0006488"(dolichol-linked oligosaccharide biosynthetic process)|go:"GO:0016021"(integral component of membrane)|go:"GO:0052925"("dol-P-Man:Man(5)GlcNAc(2)-PP-Dol alpha-1,3-mannosyltransferase activity")|interpro:IPR007873(ALG3)|reactome:R-HSA-446193|reactome:R-HSA-4720475	-	-	-	figure legend:Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2020/03/10	2020/03/11	rogid:kEEoEjyJ1AaViUhZL5Rx7o2Du+o9606	rogid:/aBCE7QqVCyHZDzq3oSoqtiDlBI9606	rigid:LlJOPwNcPHz2CI2LaM3psT/0o0M	false	sufficient binding region:26-263	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q27J81	uniprotkb:Q92685	intact:EBI-2557882|uniprotkb:Q6PK22|uniprotkb:Q86TR7|uniprotkb:Q9H6N1|uniprotkb:Q9BRM1|uniprotkb:Q27J83|uniprotkb:Q69YL8|uniprotkb:Q6P1X7|intact:EBI-28987364|ensembl:ENSP00000376410	intact:EBI-2848814|uniprotkb:A8JZZ6|uniprotkb:Q9BT71|ensembl:ENSP00000380793	psi-mi:inf2_human(display_long)|uniprotkb:INF2(gene name)|psi-mi:INF2(display_short)|uniprotkb:C14orf151(gene name synonym)|uniprotkb:C14orf173(gene name synonym)|uniprotkb:HBEBP2-binding protein C(gene name synonym)	psi-mi:alg3_human(display_long)|uniprotkb:ALG3(gene name)|psi-mi:ALG3(display_short)|uniprotkb:Asparagine-linked glycosylation protein 3 homolog(gene name synonym)|uniprotkb:"Dol-P-Man-dependent alpha(1-3)-mannosyltransferase"(gene name synonym)|uniprotkb:"Dolichyl-P-Man:Man(5)GlcNAc(2)-PP-dolichyl mannosyltransferase"(gene name synonym)|uniprotkb:Dolichyl-phosphate-mannose--glycolipid alpha-mannosyltransferase(gene name synonym)|uniprotkb:NOT(gene name synonym)|uniprotkb:NOT56L(gene name synonym)|uniprotkb:Not56-like protein(gene name synonym)	psi-mi:"MI:0018"(two hybrid)	Hacker et al. (2018)	imex:IM-28062|pubmed:29547901	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0486"(UniProt)	intact:EBI-25468462|imex:IM-28062-33	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001026884.3|refseq:NP_071934.3|refseq:NP_116103.1|ensembl:ENSG00000203485(gene)|ensembl:ENST00000392634(transcript)|go:"GO:0003779"(actin binding)|go:"GO:0030036"(actin cytoskeleton organization)|go:"GO:0031267"(small GTPase binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0090140"(regulation of mitochondrial fission)|interpro:IPR003124(Actin-binding WH2)|interpro:IPR010472(Diaphanous FH3)|interpro:IPR010473(Diaphanous GTPase-binding)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR014768(GTPase-binding/formin homology 3)|interpro:IPR015425(Actin-binding FH2)|interpro:IPR016024(Armadillo-type fold)|mint:Q27J81|interpro:IPR027649|interpro:IPR042201|ensembl:ENST00000330634|ensembl:ENSP00000376406|ensembl:ENSP00000376410|ensembl:ENST00000398337|ensembl:ENSP00000381380	refseq:NP_005778.1|refseq:NP_001006942.1|ensembl:ENSG00000214160(gene)|ensembl:ENST00000397676(transcript)|go:"GO:0000033"(alpha-1,3-mannosyltransferase activity)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006486"(protein glycosylation)|go:"GO:0006488"(dolichol-linked oligosaccharide biosynthetic process)|go:"GO:0016021"(integral component of membrane)|go:"GO:0052925"("dol-P-Man:Man(5)GlcNAc(2)-PP-Dol alpha-1,3-mannosyltransferase activity")|interpro:IPR007873(ALG3)|reactome:R-HSA-446193|reactome:R-HSA-4720475	-	-	-	figure legend:Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2020/03/10	2020/03/11	rogid:Vtx6fZtKGr2qGWX70naf5REXWTw9606	rogid:/aBCE7QqVCyHZDzq3oSoqtiDlBI9606	rigid:04SpaWnhpPgg3U2jDP9zXrDE02M	false	sufficient binding region:567-849	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:P00414	uniprotkb:Q92685	intact:EBI-3932264|uniprotkb:Q14Y83|ensembl:ENSP00000354982	intact:EBI-2848814|uniprotkb:A8JZZ6|uniprotkb:Q9BT71|ensembl:ENSP00000380793	psi-mi:cox3_human(display_long)|uniprotkb:MT-CO3(gene name)|psi-mi:MT-CO3(display_short)|uniprotkb:COIII(gene name synonym)|uniprotkb:COXIII(gene name synonym)|uniprotkb:MTCO3(gene name synonym)|uniprotkb:Cytochrome c oxidase polypeptide III(gene name synonym)	psi-mi:alg3_human(display_long)|uniprotkb:ALG3(gene name)|psi-mi:ALG3(display_short)|uniprotkb:Asparagine-linked glycosylation protein 3 homolog(gene name synonym)|uniprotkb:"Dol-P-Man-dependent alpha(1-3)-mannosyltransferase"(gene name synonym)|uniprotkb:"Dolichyl-P-Man:Man(5)GlcNAc(2)-PP-dolichyl mannosyltransferase"(gene name synonym)|uniprotkb:Dolichyl-phosphate-mannose--glycolipid alpha-mannosyltransferase(gene name synonym)|uniprotkb:NOT(gene name synonym)|uniprotkb:NOT56L(gene name synonym)|uniprotkb:Not56-like protein(gene name synonym)	psi-mi:"MI:0018"(two hybrid)	Hacker et al. (2018)	imex:IM-28062|pubmed:29547901	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0486"(UniProt)	intact:EBI-25468468|imex:IM-28062-13	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000198938(gene)|ensembl:ENST00000362079(transcript)|go:"GO:0004129"(cytochrome-c oxidase activity)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0006123"(mitochondrial electron transport, cytochrome c to oxygen)|go:"GO:0008535"(respiratory chain complex IV assembly)|go:"GO:0009055"(electron transfer activity)|go:"GO:0009060"(aerobic respiration)|go:"GO:0015453"(oxidoreduction-driven active transmembrane transporter activity)|go:"GO:0016021"(integral component of membrane)|go:"GO:0045277"(respiratory chain complex IV)|interpro:IPR000298(Cytochrome c oxidase, subunit III)|interpro:IPR013833(Cytochrome c oxidase, subunit III, 4-helical bundle)|interpro:IPR024791|interpro:IPR033945|interpro:IPR035973|rcsb pdb:5Z62|reactome:R-HSA-5628897|reactome:R-HSA-611105|reactome:R-HSA-9707564|refseq:YP_003024032.1	refseq:NP_005778.1|refseq:NP_001006942.1|ensembl:ENSG00000214160(gene)|ensembl:ENST00000397676(transcript)|go:"GO:0000033"(alpha-1,3-mannosyltransferase activity)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006486"(protein glycosylation)|go:"GO:0006488"(dolichol-linked oligosaccharide biosynthetic process)|go:"GO:0016021"(integral component of membrane)|go:"GO:0052925"("dol-P-Man:Man(5)GlcNAc(2)-PP-Dol alpha-1,3-mannosyltransferase activity")|interpro:IPR007873(ALG3)|reactome:R-HSA-446193|reactome:R-HSA-4720475	-	-	-	figure legend:Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2020/03/10	2020/03/11	rogid:ZsGHu+XXEfFZZecGf4EIhwQejAA9606	rogid:/aBCE7QqVCyHZDzq3oSoqtiDlBI9606	rigid:+JYNdH5tQsoRHBq3SloNmpeDaCE	false	sufficient binding region:151-261	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:O43889-2	uniprotkb:Q92685	intact:EBI-625022|ensembl:ENSP00000342136	intact:EBI-2848814|uniprotkb:A8JZZ6|uniprotkb:Q9BT71|ensembl:ENSP00000380793	psi-mi:o43889-2(display_long)|uniprotkb:CREB3(gene name)|psi-mi:CREB3(display_short)|uniprotkb:LZIP(gene name synonym)|uniprotkb:Luman(gene name synonym)|uniprotkb:Transcription factor LZIP-alpha(gene name synonym)|uniprotkb:LZIP(isoform synonym)|uniprotkb:Leucine zipper protein(gene name synonym)	psi-mi:alg3_human(display_long)|uniprotkb:ALG3(gene name)|psi-mi:ALG3(display_short)|uniprotkb:Asparagine-linked glycosylation protein 3 homolog(gene name synonym)|uniprotkb:"Dol-P-Man-dependent alpha(1-3)-mannosyltransferase"(gene name synonym)|uniprotkb:"Dolichyl-P-Man:Man(5)GlcNAc(2)-PP-dolichyl mannosyltransferase"(gene name synonym)|uniprotkb:Dolichyl-phosphate-mannose--glycolipid alpha-mannosyltransferase(gene name synonym)|uniprotkb:NOT(gene name synonym)|uniprotkb:NOT56L(gene name synonym)|uniprotkb:Not56-like protein(gene name synonym)	psi-mi:"MI:0018"(two hybrid)	Hacker et al. (2018)	imex:IM-28062|pubmed:29547901	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0486"(UniProt)	intact:EBI-25468474|imex:IM-28062-35	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	intact:EBI-625002(creb3_human)|ensembl:ENSG00000107175(gene)|ensembl:ENST00000353704(transcript)|uniprotkb:O43889-2(isoform-parent)	refseq:NP_005778.1|refseq:NP_001006942.1|ensembl:ENSG00000214160(gene)|ensembl:ENST00000397676(transcript)|go:"GO:0000033"(alpha-1,3-mannosyltransferase activity)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006486"(protein glycosylation)|go:"GO:0006488"(dolichol-linked oligosaccharide biosynthetic process)|go:"GO:0016021"(integral component of membrane)|go:"GO:0052925"("dol-P-Man:Man(5)GlcNAc(2)-PP-Dol alpha-1,3-mannosyltransferase activity")|interpro:IPR007873(ALG3)|reactome:R-HSA-446193|reactome:R-HSA-4720475	-	-	-	figure legend:Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2020/03/10	2020/03/11	rogid:Andi9EyhbV1LcRtj2NFt7+UWJho9606	rogid:/aBCE7QqVCyHZDzq3oSoqtiDlBI9606	rigid:hPD6icB3PNANM/Am/NQKW2CJJXQ	false	sufficient binding region:1-253	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:O43889	uniprotkb:Q92685	intact:EBI-625002|uniprotkb:O14671|uniprotkb:O14919|uniprotkb:Q96GK8|uniprotkb:Q9H2W3|uniprotkb:Q9UE77|ensembl:ENSP00000342136|uniprotkb:D0PTW6|uniprotkb:Q5TCV1	intact:EBI-2848814|uniprotkb:A8JZZ6|uniprotkb:Q9BT71|ensembl:ENSP00000380793	psi-mi:creb3_human(display_long)|uniprotkb:Luman(gene name synonym)|uniprotkb:Transcription factor LZIP-alpha(gene name synonym)|uniprotkb:CREB3(gene name)|psi-mi:CREB3(display_short)|uniprotkb:LZIP(gene name synonym)|uniprotkb:Leucine zipper protein(gene name synonym)	psi-mi:alg3_human(display_long)|uniprotkb:ALG3(gene name)|psi-mi:ALG3(display_short)|uniprotkb:Asparagine-linked glycosylation protein 3 homolog(gene name synonym)|uniprotkb:"Dol-P-Man-dependent alpha(1-3)-mannosyltransferase"(gene name synonym)|uniprotkb:"Dolichyl-P-Man:Man(5)GlcNAc(2)-PP-dolichyl mannosyltransferase"(gene name synonym)|uniprotkb:Dolichyl-phosphate-mannose--glycolipid alpha-mannosyltransferase(gene name synonym)|uniprotkb:NOT(gene name synonym)|uniprotkb:NOT56L(gene name synonym)|uniprotkb:Not56-like protein(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Hacker et al. (2018)	imex:IM-28062|pubmed:29547901	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0486"(UniProt)	intact:EBI-25473427|imex:IM-28062-45	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000107175(gene)|ensembl:ENST00000353704(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0000785"(chromatin)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001558"(regulation of cell growth)|go:"GO:0002230"(positive regulation of defense response to virus by host)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006935"(chemotaxis)|go:"GO:0006990"(positive regulation of transcription from RNA polymerase II promoter involved in unfolded protein response)|go:"GO:0008140"(cAMP response element binding protein binding)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016604"(nuclear body)|go:"GO:0019043"(establishment of viral latency)|go:"GO:0019046"(release from viral latency)|go:"GO:0045786"(negative regulation of cell cycle)|go:"GO:0030176"(integral component of endoplasmic reticulum membrane)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046983"(protein dimerization activity)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0031726"(CCR1 chemokine receptor binding)|go:"GO:0034976"(response to endoplasmic reticulum stress)|go:"GO:0050930"(induction of positive chemotaxis)|go:"GO:0051928"(positive regulation of calcium ion transport)|go:"GO:0090026"(positive regulation of monocyte chemotaxis)|go:"GO:0090045"(positive regulation of deacetylase activity)|go:"GO:1902236"(negative regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR004827("Basic-leucine zipper (bZIP) transcription factor")|interpro:IPR029808|mint:O43889|reactome:R-HSA-8874211|go:"GO:0035497"(cAMP response element binding)|go:"GO:0042127"(regulation of cell population proliferation)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0042994"(cytoplasmic sequestering of transcription factor)|go:"GO:0043025"(neuronal cell body)|refseq:NP_006359.3|dip:DIP-33935N	refseq:NP_005778.1|refseq:NP_001006942.1|ensembl:ENSG00000214160(gene)|ensembl:ENST00000397676(transcript)|go:"GO:0000033"(alpha-1,3-mannosyltransferase activity)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006486"(protein glycosylation)|go:"GO:0006488"(dolichol-linked oligosaccharide biosynthetic process)|go:"GO:0016021"(integral component of membrane)|go:"GO:0052925"("dol-P-Man:Man(5)GlcNAc(2)-PP-Dol alpha-1,3-mannosyltransferase activity")|interpro:IPR007873(ALG3)|reactome:R-HSA-446193|reactome:R-HSA-4720475	-	-	-	figure legend:Fig. 3D|comment:Molecular weight determination suggests a cleaved  N-glycosylated form of  CREB3 is sufficient to bind.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2020/03/10	2020/03/19	rogid:Andi9EyhbV1LcRtj2NFt7+UWJho9606	rogid:/aBCE7QqVCyHZDzq3oSoqtiDlBI9606	rigid:hPD6icB3PNANM/Am/NQKW2CJJXQ	false	-	enhanced green fluorescent protein tag:c-c	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:Q16563	uniprotkb:Q92685	intact:EBI-2800683|uniprotkb:A4D0R2|uniprotkb:Q96AR8|ensembl:ENSP00000011473	intact:EBI-2848814|uniprotkb:A8JZZ6|uniprotkb:Q9BT71|ensembl:ENSP00000380793	psi-mi:sypl1_human(display_long)|uniprotkb:SYPL(gene name synonym)|uniprotkb:Pantophysin(gene name synonym)|uniprotkb:SYPL1(gene name)|psi-mi:SYPL1(display_short)	psi-mi:alg3_human(display_long)|uniprotkb:ALG3(gene name)|psi-mi:ALG3(display_short)|uniprotkb:Asparagine-linked glycosylation protein 3 homolog(gene name synonym)|uniprotkb:"Dol-P-Man-dependent alpha(1-3)-mannosyltransferase"(gene name synonym)|uniprotkb:"Dolichyl-P-Man:Man(5)GlcNAc(2)-PP-dolichyl mannosyltransferase"(gene name synonym)|uniprotkb:Dolichyl-phosphate-mannose--glycolipid alpha-mannosyltransferase(gene name synonym)|uniprotkb:NOT(gene name synonym)|uniprotkb:NOT56L(gene name synonym)|uniprotkb:Not56-like protein(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Hacker et al. (2018)	imex:IM-28062|pubmed:29547901	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0486"(UniProt)	intact:EBI-25473519|imex:IM-28062-19	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_006745.1|refseq:NP_874384.1|ensembl:ENSG00000008282(gene)|ensembl:ENST00000011473(transcript)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0007268"(chemical synaptic transmission)|go:"GO:0016021"(integral component of membrane)|go:"GO:0017075"(syntaxin-1 binding)|go:"GO:0030141"(secretory granule)|go:"GO:0030285"(integral component of synaptic vesicle membrane)|go:"GO:0030672"(synaptic vesicle membrane)|go:"GO:0042470"(melanosome)|go:"GO:0070062"(extracellular exosome)|interpro:IPR001285(Synaptophysin/synaptoporin)|interpro:IPR008253(Marvel)	refseq:NP_005778.1|refseq:NP_001006942.1|ensembl:ENSG00000214160(gene)|ensembl:ENST00000397676(transcript)|go:"GO:0000033"(alpha-1,3-mannosyltransferase activity)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006486"(protein glycosylation)|go:"GO:0006488"(dolichol-linked oligosaccharide biosynthetic process)|go:"GO:0016021"(integral component of membrane)|go:"GO:0052925"("dol-P-Man:Man(5)GlcNAc(2)-PP-Dol alpha-1,3-mannosyltransferase activity")|interpro:IPR007873(ALG3)|reactome:R-HSA-446193|reactome:R-HSA-4720475	-	-	-	figure legend:Fig. 4D|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2020/03/10	2020/03/19	rogid:kw4EuKqd6PhotpKiicCjB99ZZCY9606	rogid:/aBCE7QqVCyHZDzq3oSoqtiDlBI9606	rigid:WMFKhUtiSytCPyyngVcH591AMks	false	-	enhanced green fluorescent protein tag:c-c	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:O43889	uniprotkb:Q92685	intact:EBI-625002|uniprotkb:O14671|uniprotkb:O14919|uniprotkb:Q96GK8|uniprotkb:Q9H2W3|uniprotkb:Q9UE77|ensembl:ENSP00000342136|uniprotkb:D0PTW6|uniprotkb:Q5TCV1	intact:EBI-2848814|uniprotkb:A8JZZ6|uniprotkb:Q9BT71|ensembl:ENSP00000380793	psi-mi:creb3_human(display_long)|uniprotkb:Luman(gene name synonym)|uniprotkb:Transcription factor LZIP-alpha(gene name synonym)|uniprotkb:CREB3(gene name)|psi-mi:CREB3(display_short)|uniprotkb:LZIP(gene name synonym)|uniprotkb:Leucine zipper protein(gene name synonym)	psi-mi:alg3_human(display_long)|uniprotkb:ALG3(gene name)|psi-mi:ALG3(display_short)|uniprotkb:Asparagine-linked glycosylation protein 3 homolog(gene name synonym)|uniprotkb:"Dol-P-Man-dependent alpha(1-3)-mannosyltransferase"(gene name synonym)|uniprotkb:"Dolichyl-P-Man:Man(5)GlcNAc(2)-PP-dolichyl mannosyltransferase"(gene name synonym)|uniprotkb:Dolichyl-phosphate-mannose--glycolipid alpha-mannosyltransferase(gene name synonym)|uniprotkb:NOT(gene name synonym)|uniprotkb:NOT56L(gene name synonym)|uniprotkb:Not56-like protein(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Hacker et al. (2018)	imex:IM-28062|pubmed:29547901	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0486"(UniProt)	intact:EBI-25473462|imex:IM-28062-15	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000107175(gene)|ensembl:ENST00000353704(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0000785"(chromatin)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001558"(regulation of cell growth)|go:"GO:0002230"(positive regulation of defense response to virus by host)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006935"(chemotaxis)|go:"GO:0006990"(positive regulation of transcription from RNA polymerase II promoter involved in unfolded protein response)|go:"GO:0008140"(cAMP response element binding protein binding)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016604"(nuclear body)|go:"GO:0019043"(establishment of viral latency)|go:"GO:0019046"(release from viral latency)|go:"GO:0045786"(negative regulation of cell cycle)|go:"GO:0030176"(integral component of endoplasmic reticulum membrane)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046983"(protein dimerization activity)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0031726"(CCR1 chemokine receptor binding)|go:"GO:0034976"(response to endoplasmic reticulum stress)|go:"GO:0050930"(induction of positive chemotaxis)|go:"GO:0051928"(positive regulation of calcium ion transport)|go:"GO:0090026"(positive regulation of monocyte chemotaxis)|go:"GO:0090045"(positive regulation of deacetylase activity)|go:"GO:1902236"(negative regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR004827("Basic-leucine zipper (bZIP) transcription factor")|interpro:IPR029808|mint:O43889|reactome:R-HSA-8874211|go:"GO:0035497"(cAMP response element binding)|go:"GO:0042127"(regulation of cell population proliferation)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0042994"(cytoplasmic sequestering of transcription factor)|go:"GO:0043025"(neuronal cell body)|refseq:NP_006359.3|dip:DIP-33935N	refseq:NP_005778.1|refseq:NP_001006942.1|ensembl:ENSG00000214160(gene)|ensembl:ENST00000397676(transcript)|go:"GO:0000033"(alpha-1,3-mannosyltransferase activity)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006486"(protein glycosylation)|go:"GO:0006488"(dolichol-linked oligosaccharide biosynthetic process)|go:"GO:0016021"(integral component of membrane)|go:"GO:0052925"("dol-P-Man:Man(5)GlcNAc(2)-PP-Dol alpha-1,3-mannosyltransferase activity")|interpro:IPR007873(ALG3)|reactome:R-HSA-446193|reactome:R-HSA-4720475	-	-	-	figure legend:Fig. 3E|comment:Molecular weight determination suggests a cleaved  N-glycosylated form of  CREB3 is sufficient to bind.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells)	-	2020/03/10	2020/03/19	rogid:Andi9EyhbV1LcRtj2NFt7+UWJho9606	rogid:/aBCE7QqVCyHZDzq3oSoqtiDlBI9606	rigid:hPD6icB3PNANM/Am/NQKW2CJJXQ	false	enhanced green fluorescent protein tag:c-c	-	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:P22059	uniprotkb:Q92685	intact:EBI-2681902|uniprotkb:Q6P524|ensembl:ENSP00000263847	intact:EBI-2848814|uniprotkb:A8JZZ6|uniprotkb:Q9BT71|ensembl:ENSP00000380793	psi-mi:osbp1_human(display_long)|uniprotkb:OSBP1(gene name synonym)|uniprotkb:OSBP(gene name)|psi-mi:OSBP(display_short)	psi-mi:alg3_human(display_long)|uniprotkb:ALG3(gene name)|psi-mi:ALG3(display_short)|uniprotkb:Asparagine-linked glycosylation protein 3 homolog(gene name synonym)|uniprotkb:"Dol-P-Man-dependent alpha(1-3)-mannosyltransferase"(gene name synonym)|uniprotkb:"Dolichyl-P-Man:Man(5)GlcNAc(2)-PP-dolichyl mannosyltransferase"(gene name synonym)|uniprotkb:Dolichyl-phosphate-mannose--glycolipid alpha-mannosyltransferase(gene name synonym)|uniprotkb:NOT(gene name synonym)|uniprotkb:NOT56L(gene name synonym)|uniprotkb:Not56-like protein(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Hacker et al. (2018)	imex:IM-28062|pubmed:29547901	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0486"(UniProt)	intact:EBI-25473483|imex:IM-28062-37	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_002547.1|ensembl:ENSG00000110048(gene)|ensembl:ENST00000263847(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006699"(bile acid biosynthetic process)|go:"GO:0008142"(oxysterol binding)|go:"GO:0015248"(sterol transporter activity)|go:"GO:0015918"(sterol transport)|go:"GO:0016020"(membrane)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030054"(cell junction)|go:"GO:0032367"(intracellular cholesterol transport)|go:"GO:0032934"(sterol binding)|go:"GO:0035774"(positive regulation of insulin secretion involved in cellular response to glucose stimulus)|go:"GO:0042531"(positive regulation of tyrosine phosphorylation of STAT protein)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0070273"(phosphatidylinositol-4-phosphate binding)|go:"GO:0097038"(perinuclear endoplasmic reticulum)|go:"GO:0120015"(sterol transfer activity)|go:"GO:1904411"(positive regulation of secretory granule organization)|interpro:IPR000648(Oxysterol-binding protein)|interpro:IPR018494|interpro:IPR037239|rcsb pdb:2RR3|reactome:R-HSA-1660661|reactome:R-HSA-192105|interpro:IPR001849(Pleckstrin-like)|interpro:IPR011993(Pleckstrin homology-type)	refseq:NP_005778.1|refseq:NP_001006942.1|ensembl:ENSG00000214160(gene)|ensembl:ENST00000397676(transcript)|go:"GO:0000033"(alpha-1,3-mannosyltransferase activity)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006486"(protein glycosylation)|go:"GO:0006488"(dolichol-linked oligosaccharide biosynthetic process)|go:"GO:0016021"(integral component of membrane)|go:"GO:0052925"("dol-P-Man:Man(5)GlcNAc(2)-PP-Dol alpha-1,3-mannosyltransferase activity")|interpro:IPR007873(ALG3)|reactome:R-HSA-446193|reactome:R-HSA-4720475	-	-	-	figure legend:Fig. 4A|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-skbr3)|taxid:9606(Homo sapiens SKBR3)	-	2020/03/10	2020/03/19	rogid:9LgzhfWQ0E/ECTTKA1OogQSyuAI9606	rogid:/aBCE7QqVCyHZDzq3oSoqtiDlBI9606	rigid:N5y+7Zmh0cnZNCx5AvGfXR+ToW4	false	-	green fluorescent protein tag:c-c	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:Q96SU4	uniprotkb:Q92685	intact:EBI-2511368|ensembl:ENSP00000407168|uniprotkb:Q6IA67|uniprotkb:Q9H9X2|uniprotkb:Q96SK4|uniprotkb:B1AKJ8|uniprotkb:Q5TFC0|uniprotkb:Q8NB17|uniprotkb:Q8TAS8|uniprotkb:D3DQ31|uniprotkb:B3KPQ4|uniprotkb:Q86YQ3	intact:EBI-2848814|uniprotkb:A8JZZ6|uniprotkb:Q9BT71|ensembl:ENSP00000380793	psi-mi:osbl9_human(display_long)|uniprotkb:OSBPL9(gene name)|psi-mi:OSBPL9(display_short)|uniprotkb:ORP9(gene name synonym)|uniprotkb:OSBP4(gene name synonym)	psi-mi:alg3_human(display_long)|uniprotkb:ALG3(gene name)|psi-mi:ALG3(display_short)|uniprotkb:Asparagine-linked glycosylation protein 3 homolog(gene name synonym)|uniprotkb:"Dol-P-Man-dependent alpha(1-3)-mannosyltransferase"(gene name synonym)|uniprotkb:"Dolichyl-P-Man:Man(5)GlcNAc(2)-PP-dolichyl mannosyltransferase"(gene name synonym)|uniprotkb:Dolichyl-phosphate-mannose--glycolipid alpha-mannosyltransferase(gene name synonym)|uniprotkb:NOT(gene name synonym)|uniprotkb:NOT56L(gene name synonym)|uniprotkb:Not56-like protein(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Hacker et al. (2018)	imex:IM-28062|pubmed:29547901	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0486"(UniProt)	intact:EBI-25473491|imex:IM-28062-47	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000117859(gene)|ensembl:ENST00000428468(transcript)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0006699"(bile acid biosynthetic process)|go:"GO:0015248"(sterol transporter activity)|go:"GO:0016020"(membrane)|go:"GO:0031902"(late endosome membrane)|go:"GO:0032934"(sterol binding)|go:"GO:0043231"(intracellular membrane-bounded organelle)|interpro:IPR000648(Oxysterol-binding protein)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR018494|interpro:IPR037239|mint:Q96SU4|reactome:R-HSA-192105|refseq:XP_011538905.1|refseq:XP_011538906.1|refseq:NP_078862.4|refseq:NP_683702.1|refseq:NP_683703.1|refseq:NP_683705.1|refseq:NP_683706.3|refseq:NP_683704.2|refseq:NP_683707.3|refseq:XP_006710386.1|refseq:XP_006710387.1|refseq:XP_006710388.1|refseq:XP_006710389.1|refseq:NP_001317509.1|refseq:XP_016855708.1|refseq:XP_016855709.1|refseq:XP_016855710.1	refseq:NP_005778.1|refseq:NP_001006942.1|ensembl:ENSG00000214160(gene)|ensembl:ENST00000397676(transcript)|go:"GO:0000033"(alpha-1,3-mannosyltransferase activity)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006486"(protein glycosylation)|go:"GO:0006488"(dolichol-linked oligosaccharide biosynthetic process)|go:"GO:0016021"(integral component of membrane)|go:"GO:0052925"("dol-P-Man:Man(5)GlcNAc(2)-PP-Dol alpha-1,3-mannosyltransferase activity")|interpro:IPR007873(ALG3)|reactome:R-HSA-446193|reactome:R-HSA-4720475	-	-	-	figure legend:Fig. 4B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-skbr3)|taxid:9606(Homo sapiens SKBR3)	-	2020/03/10	2020/03/19	rogid:2XLQ0JD4BEKGoyiwd/63YTmyVlE9606	rogid:/aBCE7QqVCyHZDzq3oSoqtiDlBI9606	rigid:ofv4GAB2DoCGlNyOFfcMNOcnEoM	false	-	green fluorescent protein tag:c-c	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:Q07954	uniprotkb:Q92685	intact:EBI-1046087|uniprotkb:Q8IVG8|uniprotkb:Q2PP12|uniprotkb:Q86SW0|ensembl:ENSP00000243077	intact:EBI-2848814|uniprotkb:A8JZZ6|uniprotkb:Q9BT71|ensembl:ENSP00000380793	psi-mi:lrp1_human(display_long)|uniprotkb:Alpha-2-macroglobulin receptor(gene name synonym)|uniprotkb:Apolipoprotein E receptor(gene name synonym)|uniprotkb:LRP1(gene name)|psi-mi:LRP1(display_short)|uniprotkb:A2MR(gene name synonym)|uniprotkb:APR(gene name synonym)	psi-mi:alg3_human(display_long)|uniprotkb:ALG3(gene name)|psi-mi:ALG3(display_short)|uniprotkb:Asparagine-linked glycosylation protein 3 homolog(gene name synonym)|uniprotkb:"Dol-P-Man-dependent alpha(1-3)-mannosyltransferase"(gene name synonym)|uniprotkb:"Dolichyl-P-Man:Man(5)GlcNAc(2)-PP-dolichyl mannosyltransferase"(gene name synonym)|uniprotkb:Dolichyl-phosphate-mannose--glycolipid alpha-mannosyltransferase(gene name synonym)|uniprotkb:NOT(gene name synonym)|uniprotkb:NOT56L(gene name synonym)|uniprotkb:Not56-like protein(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Hacker et al. (2018)	imex:IM-28062|pubmed:29547901	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0486"(UniProt)	intact:EBI-25473498|imex:IM-28062-39	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_002323.2|ensembl:ENSG00000123384(gene)|ensembl:ENST00000243077(transcript)|go:"GO:0001523"(retinoid metabolic process)|go:"GO:0001540"(amyloid-beta binding)|go:"GO:0002020"(protease binding)|go:"GO:0002265"(astrocyte activation involved in immune response)|go:"GO:0003723"(RNA binding)|go:"GO:0005041"(low-density lipoprotein particle receptor activity)|go:"GO:0005044"(scavenger receptor activity)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005634"(nucleus)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005769"(early endosome)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0005905"(clathrin-coated pit)|go:"GO:0005925"(focal adhesion)|go:"GO:0006629"(lipid metabolic process)|go:"GO:0006898"(receptor-mediated endocytosis)|go:"GO:0006909"(phagocytosis)|go:"GO:0007041"(lysosomal transport)|go:"GO:0007204"(positive regulation of cytosolic calcium ion concentration)|go:"GO:0007205"(protein kinase C-activating G protein-coupled receptor signaling pathway)|go:"GO:0007568"(aging)|go:"GO:0008283"(cell population proliferation)|go:"GO:0010715"(regulation of extracellular matrix disassembly)|go:"GO:0010875"(positive regulation of cholesterol efflux)|go:"GO:0010942"(positive regulation of cell death)|go:"GO:0010977"(negative regulation of neuron projection development)|go:"GO:0014912"(negative regulation of smooth muscle cell migration)|go:"GO:0015026"(coreceptor activity)|go:"GO:0016020"(membrane)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016964"(alpha-2 macroglobulin receptor activity)|go:"GO:0021987"(cerebral cortex development)|go:"GO:0030136"(clathrin-coated vesicle)|go:"GO:0030178"(negative regulation of Wnt signaling pathway)|go:"GO:0030226"(apolipoprotein receptor activity)|go:"GO:0030425"(dendrite)|go:"GO:0030666"(endocytic vesicle membrane)|go:"GO:0031623"(receptor internalization)|go:"GO:0032050"(clathrin heavy chain binding)|go:"GO:0032092"(positive regulation of protein binding)|go:"GO:0032370"(positive regulation of lipid transport)|go:"GO:0032374"(regulation of cholesterol transport)|go:"GO:0032429"(regulation of phospholipase A2 activity)|go:"GO:0032593"(insulin-responsive compartment)|go:"GO:0032956"(regulation of actin cytoskeleton organization)|go:"GO:0034185"(apolipoprotein binding)|go:"GO:0035774"(positive regulation of insulin secretion involved in cellular response to glucose stimulus)|go:"GO:0035909"(aorta morphogenesis)|go:"GO:0038023"(signaling receptor activity)|go:"GO:0038024"(cargo receptor activity)|go:"GO:0042157"(lipoprotein metabolic process)|go:"GO:0042953"(lipoprotein transport)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043235"(receptor complex)|go:"GO:0043277"(apoptotic cell clearance)|go:"GO:0043395"(heparan sulfate proteoglycan binding)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0044242"(cellular lipid catabolic process)|go:"GO:0044295"(axonal growth cone)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045056"(transcytosis)|go:"GO:0045177"(apical part of cell)|go:"GO:0045807"(positive regulation of endocytosis)|go:"GO:0048691"(positive regulation of axon extension involved in regeneration)|go:"GO:0048694"(positive regulation of collateral sprouting of injured axon)|go:"GO:0050766"(positive regulation of phagocytosis)|go:"GO:0051481"(negative regulation of cytosolic calcium ion concentration)|go:"GO:0051895"(negative regulation of focal adhesion assembly)|go:"GO:0061642"(chemoattraction of axon)|go:"GO:0070325"(lipoprotein particle receptor binding)|go:"GO:0070374"(positive regulation of ERK1 and ERK2 cascade)|go:"GO:0097242"(amyloid-beta clearance)|go:"GO:0098797"(plasma membrane protein complex)|go:"GO:0150093"(amyloid-beta clearance by transcytosis)|go:"GO:0150094"(amyloid-beta clearance by cellular catabolic process)|go:"GO:0150104"(transport across blood-brain barrier)|go:"GO:1900149"(positive regulation of Schwann cell migration)|go:"GO:1900223"(positive regulation of amyloid-beta clearance)|go:"GO:1903078"(positive regulation of protein localization to plasma membrane)|go:"GO:1904109"(positive regulation of cholesterol import)|go:"GO:1904300"(positive regulation of transcytosis)|go:"GO:1904646"(cellular response to amyloid-beta)|go:"GO:1904754"(positive regulation of vascular associated smooth muscle cell migration)|go:"GO:1905049"(negative regulation of metallopeptidase activity)|go:"GO:1905167"(positive regulation of lysosomal protein catabolic process)|go:"GO:2000343"("positive regulation of chemokine (C-X-C motif) ligand 2 production")|go:"GO:2000587"(negative regulation of platelet-derived growth factor receptor-beta signaling pathway)|interpro:IPR000033(Low-density lipoprotein receptor, YWTD repeat)|interpro:IPR000152(Aspartic acid and asparagine hydroxylation site)|interpro:IPR000742(EGF-like, type 3)|interpro:IPR001881(EGF-like calcium-binding)|interpro:IPR002172(Low density lipoprotein-receptor, class A, cysteine-rich)|interpro:IPR009030(Growth factor, receptor)|interpro:IPR011042(Six-bladed beta-propeller, TolB-like)|interpro:IPR018097|interpro:IPR023415|interpro:IPR026823|interpro:IPR032485|interpro:IPR036055|rcsb pdb:1CR8|rcsb pdb:1D2L|rcsb pdb:1J8E|rcsb pdb:2FYJ|rcsb pdb:2FYL|rcsb pdb:2KNX|rcsb pdb:2KNY|reactome:R-HSA-2168880|reactome:R-HSA-975634|dip:DIP-50613N	refseq:NP_005778.1|refseq:NP_001006942.1|ensembl:ENSG00000214160(gene)|ensembl:ENST00000397676(transcript)|go:"GO:0000033"(alpha-1,3-mannosyltransferase activity)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006486"(protein glycosylation)|go:"GO:0006488"(dolichol-linked oligosaccharide biosynthetic process)|go:"GO:0016021"(integral component of membrane)|go:"GO:0052925"("dol-P-Man:Man(5)GlcNAc(2)-PP-Dol alpha-1,3-mannosyltransferase activity")|interpro:IPR007873(ALG3)|reactome:R-HSA-446193|reactome:R-HSA-4720475	-	-	-	figure legend:Fig. 4C|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-mda_mb_468)|taxid:9606(Homo sapiens MDA-MB-468)	-	2020/03/10	2020/03/19	rogid:eO2l3huuq6NYoVoYdoCloLqrlRw9606	rogid:/aBCE7QqVCyHZDzq3oSoqtiDlBI9606	rigid:5jwXp6F4jem1jUwalMcPe6u+NL8	false	-	-	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:Q16563	uniprotkb:Q92685	intact:EBI-2800683|uniprotkb:A4D0R2|uniprotkb:Q96AR8|ensembl:ENSP00000011473	intact:EBI-2848814|uniprotkb:A8JZZ6|uniprotkb:Q9BT71|ensembl:ENSP00000380793	psi-mi:sypl1_human(display_long)|uniprotkb:SYPL(gene name synonym)|uniprotkb:Pantophysin(gene name synonym)|uniprotkb:SYPL1(gene name)|psi-mi:SYPL1(display_short)	psi-mi:alg3_human(display_long)|uniprotkb:ALG3(gene name)|psi-mi:ALG3(display_short)|uniprotkb:Asparagine-linked glycosylation protein 3 homolog(gene name synonym)|uniprotkb:"Dol-P-Man-dependent alpha(1-3)-mannosyltransferase"(gene name synonym)|uniprotkb:"Dolichyl-P-Man:Man(5)GlcNAc(2)-PP-dolichyl mannosyltransferase"(gene name synonym)|uniprotkb:Dolichyl-phosphate-mannose--glycolipid alpha-mannosyltransferase(gene name synonym)|uniprotkb:NOT(gene name synonym)|uniprotkb:NOT56L(gene name synonym)|uniprotkb:Not56-like protein(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Hacker et al. (2018)	imex:IM-28062|pubmed:29547901	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0486"(UniProt)	intact:EBI-25473513|imex:IM-28062-17	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_006745.1|refseq:NP_874384.1|ensembl:ENSG00000008282(gene)|ensembl:ENST00000011473(transcript)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0007268"(chemical synaptic transmission)|go:"GO:0016021"(integral component of membrane)|go:"GO:0017075"(syntaxin-1 binding)|go:"GO:0030141"(secretory granule)|go:"GO:0030285"(integral component of synaptic vesicle membrane)|go:"GO:0030672"(synaptic vesicle membrane)|go:"GO:0042470"(melanosome)|go:"GO:0070062"(extracellular exosome)|interpro:IPR001285(Synaptophysin/synaptoporin)|interpro:IPR008253(Marvel)	refseq:NP_005778.1|refseq:NP_001006942.1|ensembl:ENSG00000214160(gene)|ensembl:ENST00000397676(transcript)|go:"GO:0000033"(alpha-1,3-mannosyltransferase activity)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006486"(protein glycosylation)|go:"GO:0006488"(dolichol-linked oligosaccharide biosynthetic process)|go:"GO:0016021"(integral component of membrane)|go:"GO:0052925"("dol-P-Man:Man(5)GlcNAc(2)-PP-Dol alpha-1,3-mannosyltransferase activity")|interpro:IPR007873(ALG3)|reactome:R-HSA-446193|reactome:R-HSA-4720475	-	-	-	figure legend:Fig. 4C|comment:Molecular weight determination suggests that cleavage products of ALG3 interact with SYPL1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-mda_mb_468)|taxid:9606(Homo sapiens MDA-MB-468)	-	2020/03/10	2020/03/19	rogid:kw4EuKqd6PhotpKiicCjB99ZZCY9606	rogid:/aBCE7QqVCyHZDzq3oSoqtiDlBI9606	rigid:WMFKhUtiSytCPyyngVcH591AMks	false	-	-	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)