#ID(s) interactor A	ID(s) interactor B	Alt. ID(s) interactor A	Alt. ID(s) interactor B	Alias(es) interactor A	Alias(es) interactor B	Interaction detection method(s)	Publication 1st author(s)	Publication Identifier(s)	Taxid interactor A	Taxid interactor B	Interaction type(s)	Source database(s)	Interaction identifier(s)	Confidence value(s)	Expansion method(s)	Biological role(s) interactor A	Biological role(s) interactor B	Experimental role(s) interactor A	Experimental role(s) interactor B	Type(s) interactor A	Type(s) interactor B	Xref(s) interactor A	Xref(s) interactor B	Interaction Xref(s)	Annotation(s) interactor A	Annotation(s) interactor B	Interaction annotation(s)	Host organism(s)	Interaction parameter(s)	Creation date	Update date	Checksum(s) interactor A	Checksum(s) interactor B	Interaction Checksum(s)	Negative	Feature(s) interactor A	Feature(s) interactor B	Stoichiometry(s) interactor A	Stoichiometry(s) interactor B	Identification method participant A	Identification method participant B
uniprotkb:Q5XIE8	uniprotkb:Q9QXY2	intact:EBI-15348306|ensembl:ENSRNOP00000023037	intact:EBI-1394088|uniprotkb:Q9QXY3|ensembl:ENSRNOP00000016070	psi-mi:itm2b_rat(display_long)|uniprotkb:Itm2b(gene name)|psi-mi:Itm2b(display_short)|uniprotkb:Immature BRI2(gene name synonym)|uniprotkb:Transmembrane protein BRI(gene name synonym)	psi-mi:srcn1_rat(display_long)|uniprotkb:Srcin1(gene name)|psi-mi:Srcin1(display_short)|uniprotkb:Snip(gene name synonym)|uniprotkb:p140Cap(gene name synonym)|uniprotkb:SNAP-25-interacting protein(gene name synonym)|uniprotkb:P140(gene name synonym)|uniprotkb:p130Cas-associated protein(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Martins et al. (2018)	imex:IM-28469|pubmed:29476059	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26438079|imex:IM-28469-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSRNOG00000016271(gene)|ensembl:ENSRNOT00000023037(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001540"(amyloid-beta binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0010008"(endosome membrane)|go:"GO:0030660"(Golgi-associated vesicle membrane)|go:"GO:0031301"(integral component of organelle membrane)|go:"GO:0042985"(negative regulation of amyloid precursor protein biosynthetic process)|interpro:IPR007084(BRICHOS)|interpro:IPR040145|mint:Q5XIE8|refseq:NP_001006964.1|rgd:620727	rgd:708439|refseq:NP_062251.1|ensembl:ENSRNOG00000011475(gene)|ensembl:ENSRNOT00000016070(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0006887"(exocytosis)|go:"GO:0007162"(negative regulation of cell adhesion)|go:"GO:0014069"(postsynaptic density)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0019901"(protein kinase binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030027"(lamellipodium)|go:"GO:0030175"(filopodium)|go:"GO:0030234"(enzyme regulator activity)|go:"GO:0030334"(regulation of cell migration)|go:"GO:0030424"(axon)|go:"GO:0030425"(dendrite)|go:"GO:0034446"(substrate adhesion-dependent cell spreading)|go:"GO:0043005"(neuron projection)|go:"GO:0043025"(neuronal cell body)|go:"GO:0045202"(synapse)|go:"GO:0050709"(negative regulation of protein secretion)|go:"GO:0061001"(regulation of dendritic spine morphogenesis)|go:"GO:0061098"(positive regulation of protein tyrosine kinase activity)|go:"GO:0061099"(negative regulation of protein tyrosine kinase activity)|go:"GO:0098793"(presynapse)|interpro:IPR022782|interpro:IPR026727|mint:Q9QXY2	-	-	-	figure legend:ST1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10116(rat-brain-cerebellum)|taxid:10116(Rattus norvegicus)	-	2020/10/30	2020/10/30	rogid:DtE+ZXAZKdCMvUW5K+jXQ5bH07M10116	rogid:vpuj/e+VqyDmaw6L6ah6jUJv5kI10116	rigid:OaXQ9NA25fwCWxejPU3Ao9q5j/E	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q5XIE8	uniprotkb:Q5XI32	intact:EBI-15348306|ensembl:ENSRNOP00000023037	intact:EBI-2128068|ensembl:ENSRNOP00000010308	psi-mi:itm2b_rat(display_long)|uniprotkb:Itm2b(gene name)|psi-mi:Itm2b(display_short)|uniprotkb:Immature BRI2(gene name synonym)|uniprotkb:Transmembrane protein BRI(gene name synonym)	psi-mi:capzb_rat(display_long)|uniprotkb:Capzb(gene name)|psi-mi:Capzb(display_short)|uniprotkb:CapZ beta(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Martins et al. (2018)	imex:IM-28469|pubmed:29476059	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26438079|imex:IM-28469-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSRNOG00000016271(gene)|ensembl:ENSRNOT00000023037(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001540"(amyloid-beta binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0010008"(endosome membrane)|go:"GO:0030660"(Golgi-associated vesicle membrane)|go:"GO:0031301"(integral component of organelle membrane)|go:"GO:0042985"(negative regulation of amyloid precursor protein biosynthetic process)|interpro:IPR007084(BRICHOS)|interpro:IPR040145|mint:Q5XIE8|refseq:NP_001006964.1|rgd:620727	rgd:1359099|refseq:NP_001005903.1|ensembl:ENSRNOG00000007330(gene)|ensembl:ENSRNOT00000010308(transcript)|go:"GO:0000902"(cell morphogenesis)|go:"GO:0003779"(actin binding)|go:"GO:0005903"(brush border)|go:"GO:0007010"(cytoskeleton organization)|go:"GO:0008154"(actin polymerization or depolymerization)|go:"GO:0008290"(F-actin capping protein complex)|go:"GO:0010591"(regulation of lamellipodium assembly)|go:"GO:0014069"(postsynaptic density)|go:"GO:0016020"(membrane)|go:"GO:0022604"(regulation of cell morphogenesis)|go:"GO:0030017"(sarcomere)|go:"GO:0030027"(lamellipodium)|go:"GO:0030030"(cell projection organization)|go:"GO:0030032"(lamellipodium assembly)|go:"GO:0030863"(cortical cytoskeleton)|go:"GO:0032279"(asymmetric synapse)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043197"(dendritic spine)|go:"GO:0051015"(actin filament binding)|go:"GO:0051016"(barbed-end actin filament capping)|go:"GO:0051490"(negative regulation of filopodium assembly)|go:"GO:0071203"(WASH complex)|go:"GO:0097224"(sperm connecting piece)|go:"GO:0098685"(Schaffer collateral - CA1 synapse)|go:"GO:0098686"(hippocampal mossy fiber to CA3 synapse)|interpro:IPR001698(F-actin capping protein, beta subunit)|interpro:IPR019771|interpro:IPR037282|interpro:IPR042276|interpro:IPR043175|mint:Q5XI32|reactome:R-RNO-2132295|reactome:R-RNO-3371497|reactome:R-RNO-6807878|reactome:R-RNO-6811436|reactome:R-RNO-9013405|reactome:R-RNO-9035034|reactome:R-RNO-983231	-	-	-	figure legend:ST1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10116(rat-brain-cerebellum)|taxid:10116(Rattus norvegicus)	-	2020/10/30	2020/10/30	rogid:DtE+ZXAZKdCMvUW5K+jXQ5bH07M10116	rogid:48IQ1CJkjL9DdUW66uFlFKhRWxo10116	rigid:OaXQ9NA25fwCWxejPU3Ao9q5j/E	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q5XIE8	uniprotkb:O35179	intact:EBI-15348306|ensembl:ENSRNOP00000023037	intact:EBI-1149197|ensembl:ENSRNOP00000008999	psi-mi:itm2b_rat(display_long)|uniprotkb:Itm2b(gene name)|psi-mi:Itm2b(display_short)|uniprotkb:Immature BRI2(gene name synonym)|uniprotkb:Transmembrane protein BRI(gene name synonym)	psi-mi:sh3g2_rat(display_long)|uniprotkb:Sh3gl2(gene name)|psi-mi:Sh3gl2(display_short)|uniprotkb:Endophilin-1(gene name synonym)|uniprotkb:SH3 domain-containing GRB2-like protein 2(gene name synonym)|uniprotkb:SH3 domain protein 2A(gene name synonym)|uniprotkb:SH3p4(gene name synonym)|uniprotkb:Sh3d2a(gene name synonym)|uniprotkb:Sh3p4(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Martins et al. (2018)	imex:IM-28469|pubmed:29476059	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26438079|imex:IM-28469-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSRNOG00000016271(gene)|ensembl:ENSRNOT00000023037(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001540"(amyloid-beta binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0010008"(endosome membrane)|go:"GO:0030660"(Golgi-associated vesicle membrane)|go:"GO:0031301"(integral component of organelle membrane)|go:"GO:0042985"(negative regulation of amyloid precursor protein biosynthetic process)|interpro:IPR007084(BRICHOS)|interpro:IPR040145|mint:Q5XIE8|refseq:NP_001006964.1|rgd:620727	refseq:NP_446387.1|rgd:620276|go:"GO:0001933"(negative regulation of protein phosphorylation)|go:"GO:0002090"(regulation of receptor internalization)|go:"GO:0005769"(early endosome)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008289"(lipid binding)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0016191"(synaptic vesicle uncoating)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030672"(synaptic vesicle membrane)|go:"GO:0031175"(neuron projection development)|go:"GO:0042802"(identical protein binding)|go:"GO:0043025"(neuronal cell body)|go:"GO:0045202"(synapse)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0048488"(synaptic vesicle endocytosis)|go:"GO:0060988"(lipid tube assembly)|go:"GO:0097441"(basal dendrite)|go:"GO:0097484"(dendrite extension)|go:"GO:0097749"(membrane tubulation)|go:"GO:0097753"(membrane bending)|go:"GO:0098684"(photoreceptor ribbon synapse)|go:"GO:0098685"(Schaffer collateral - CA1 synapse)|go:"GO:0098686"(hippocampal mossy fiber to CA3 synapse)|go:"GO:0098793"(presynapse)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099050"(vesicle scission)|go:"GO:0099523"(presynaptic cytosol)|go:"GO:1903527"(positive regulation of membrane tubulation)|go:"GO:1905604"(negative regulation of blood-brain barrier permeability)|go:"GO:1990416"(cellular response to brain-derived neurotrophic factor stimulus)|go:"GO:2000369"(regulation of clathrin-dependent endocytosis)|interpro:IPR001452(Src homology-3)|interpro:IPR004148(BAR)|interpro:IPR027267|interpro:IPR035824|interpro:IPR036028|mint:O35179|rcsb pdb:2C08|rcsb pdb:2KNB|rcsb pdb:3IQL|reactome:R-RNO-177504|reactome:R-RNO-182971|ensembl:ENSRNOT00000008999(transcript)|reactome:R-RNO-2132295|reactome:R-RNO-432720|reactome:R-RNO-432722|reactome:R-RNO-437239|reactome:R-RNO-6807004|reactome:R-RNO-8856825|reactome:R-RNO-8856828|ensembl:ENSRNOG00000006761(gene)	-	-	-	figure legend:ST1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10116(rat-brain-cerebellum)|taxid:10116(Rattus norvegicus)	-	2020/10/30	2020/10/30	rogid:DtE+ZXAZKdCMvUW5K+jXQ5bH07M10116	rogid:n3a31uT/o83hN0em2h7R7+p6pi010116	rigid:OaXQ9NA25fwCWxejPU3Ao9q5j/E	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q5XIE8	uniprotkb:P52873	intact:EBI-15348306|ensembl:ENSRNOP00000023037	intact:EBI-7623445|intact:MINT-4592965|uniprotkb:Q5RKM0|uniprotkb:Q64555|ensembl:ENSRNOP00000026316|ensembl:ENSRNOP00000075317	psi-mi:itm2b_rat(display_long)|uniprotkb:Itm2b(gene name)|psi-mi:Itm2b(display_short)|uniprotkb:Immature BRI2(gene name synonym)|uniprotkb:Transmembrane protein BRI(gene name synonym)	psi-mi:pyc_rat(display_long)|uniprotkb:Pc(gene name)|psi-mi:Pc(display_short)|uniprotkb:Pyruvic carboxylase(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Martins et al. (2018)	imex:IM-28469|pubmed:29476059	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26438079|imex:IM-28469-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSRNOG00000016271(gene)|ensembl:ENSRNOT00000023037(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001540"(amyloid-beta binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0010008"(endosome membrane)|go:"GO:0030660"(Golgi-associated vesicle membrane)|go:"GO:0031301"(integral component of organelle membrane)|go:"GO:0042985"(negative regulation of amyloid precursor protein biosynthetic process)|interpro:IPR007084(BRICHOS)|interpro:IPR040145|mint:Q5XIE8|refseq:NP_001006964.1|rgd:620727	refseq:NP_036876.2|rgd:3262|ensembl:ENSRNOT00000026316(transcript)|ensembl:ENSRNOT00000082388(transcript)|go:"GO:0004736"(pyruvate carboxylase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0006090"(pyruvate metabolic process)|go:"GO:0006094"(gluconeogenesis)|go:"GO:0006107"(oxaloacetate metabolic process)|go:"GO:0006629"(lipid metabolic process)|go:"GO:0009374"(biotin binding)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0019074"(viral RNA genome packaging)|go:"GO:0031406"(carboxylic acid binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0044791"(obsolete positive regulation by host of viral release from host cell)|go:"GO:0044794"(positive regulation by host of viral process)|go:"GO:0046872"(metal ion binding)|go:"GO:0071073"(positive regulation of phospholipid biosynthetic process)|interpro:IPR000089(Biotin/lipoyl attachment)|interpro:IPR000891(Pyruvate carboxyltransferase)|interpro:IPR001882(Biotin-binding site)|interpro:IPR003379(Conserved carboxylase region)|interpro:IPR005479(Carbamoyl phosphate synthetase, large subunit, ATP-binding)|interpro:IPR005481(Carbamoyl phosphate synthase, large subunit, N-terminal)|interpro:IPR005482(Biotin carboxylase, C-terminal)|interpro:IPR005930(Pyruvate carboxylase)|interpro:IPR011053(Single hybrid motif)|ensembl:ENSRNOG00000019372(gene)|interpro:IPR011054(Rudiment single hybrid motif)|interpro:IPR011761(ATP-grasp fold)|interpro:IPR011764(Biotin carboxylation region)|interpro:IPR013815(ATP-grasp fold, subdomain 1)|interpro:IPR016185(PreATP-grasp-like fold)|mint:P52873|reactome:R-RNO-196780|reactome:R-RNO-70263|interpro:IPR013785(Aldolase-type TIM barrel)|refseq:XP_006230754.1|refseq:XP_006230755.1|refseq:XP_006230756.1	-	-	function:"Pyruvate carboxylase catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second. Catalyzes in a tissue specific manner, the initial reactions of glucose (liver, kidney) and lipid (adipose tissue, liver, brain) synthesis from pyruvate"|comment:mint	figure legend:ST1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10116(rat-brain-cerebellum)|taxid:10116(Rattus norvegicus)	-	2020/10/30	2020/10/30	rogid:DtE+ZXAZKdCMvUW5K+jXQ5bH07M10116	rogid:ETBFyZy4Cg5F4LC5eBHHHCzTkKY10116	rigid:OaXQ9NA25fwCWxejPU3Ao9q5j/E	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q5XIE8	uniprotkb:Q6QLM7	intact:EBI-15348306|ensembl:ENSRNOP00000023037	intact:EBI-8053424|intact:UNK-5485260	psi-mi:itm2b_rat(display_long)|uniprotkb:Itm2b(gene name)|psi-mi:Itm2b(display_short)|uniprotkb:Immature BRI2(gene name synonym)|uniprotkb:Transmembrane protein BRI(gene name synonym)	psi-mi:kif5a_rat(display_long)|uniprotkb:Kinesin heavy chain neuron-specific 1(gene name synonym)|uniprotkb:Neuronal kinesin heavy chain(gene name synonym)|uniprotkb:Kif5a(gene name)|psi-mi:Kif5a(display_short)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Martins et al. (2018)	imex:IM-28469|pubmed:29476059	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26438079|imex:IM-28469-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSRNOG00000016271(gene)|ensembl:ENSRNOT00000023037(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001540"(amyloid-beta binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0010008"(endosome membrane)|go:"GO:0030660"(Golgi-associated vesicle membrane)|go:"GO:0031301"(integral component of organelle membrane)|go:"GO:0042985"(negative regulation of amyloid precursor protein biosynthetic process)|interpro:IPR007084(BRICHOS)|interpro:IPR040145|mint:Q5XIE8|refseq:NP_001006964.1|rgd:620727	rgd:1303035|refseq:NP_997688.1|mint:Q6QLM7|dip:DIP-46364N|go:"GO:0008574"(plus-end-directed microtubule motor activity)|go:"GO:0016192"(vesicle-mediated transport)|go:"GO:0019894"(kinesin binding)|go:"GO:0021766"(hippocampus development)|go:"GO:0021794"(thalamus development)|go:"GO:0021987"(cerebral cortex development)|go:"GO:0030424"(axon)|go:"GO:0030425"(dendrite)|go:"GO:0030705"(cytoskeleton-dependent intracellular transport)|go:"GO:0032839"(dendrite cytoplasm)|go:"GO:0035253"(ciliary rootlet)|go:"GO:0043005"(neuron projection)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043204"(perikaryon)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0048489"(synaptic vesicle transport)|go:"GO:0048666"(neuron development)|go:"GO:0071361"(cellular response to ethanol)|go:"GO:0090724"(central region of growth cone)|go:"GO:0097110"(scaffold protein binding)|go:"GO:0097440"(apical dendrite)|go:"GO:0098971"(anterograde dendritic transport of neurotransmitter receptor complex)|go:"GO:0099641"(anterograde axonal protein transport)|go:"GO:1904115"(axon cytoplasm)|go:"GO:1904647"(response to rotenone)|go:"GO:1990049"(retrograde neuronal dense core vesicle transport)|go:"GO:1990090"(cellular response to nerve growth factor stimulus)|interpro:IPR001752(Kinesin, motor region)|interpro:IPR027640|interpro:IPR036961|rcsb pdb:2KIN|interpro:IPR027417|rcsb pdb:3KIN|reactome:R-RNO-2132295|reactome:R-RNO-5625970|reactome:R-RNO-6811434|reactome:R-RNO-983189|go:"GO:0000932"(P-body)|go:"GO:0003777"(microtubule motor activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005871"(kinesin complex)|go:"GO:0005874"(microtubule)|go:"GO:0007017"(microtubule-based process)|go:"GO:0007018"(microtubule-based movement)|go:"GO:0007411"(axon guidance)|go:"GO:0008017"(microtubule binding)	-	-	comment:mint|comment:homomint|function:"Microtubule-dependent motor required for slow axonal transport of neurofilament proteins (NFH, NFM and NFL)"	figure legend:ST1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10116(rat-brain-cerebellum)|taxid:10116(Rattus norvegicus)	-	2020/10/30	2020/10/30	rogid:DtE+ZXAZKdCMvUW5K+jXQ5bH07M10116	rogid:8Rs5XnQSfYtBkTw31UqIBAtb/wY10116	rigid:OaXQ9NA25fwCWxejPU3Ao9q5j/E	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q5XIE8	uniprotkb:Q7TQ16	intact:EBI-15348306|ensembl:ENSRNOP00000023037	intact:EBI-7626900|intact:UNK-5495741|ensembl:ENSRNOP00000065074	psi-mi:itm2b_rat(display_long)|uniprotkb:Itm2b(gene name)|psi-mi:Itm2b(display_short)|uniprotkb:Immature BRI2(gene name synonym)|uniprotkb:Transmembrane protein BRI(gene name synonym)	psi-mi:qcr8_rat(display_long)|uniprotkb:Uqcrq(gene name)|psi-mi:Uqcrq(display_short)|uniprotkb:Complex III subunit 8(gene name synonym)|uniprotkb:Complex III subunit VIII(gene name synonym)|uniprotkb:Low molecular mass ubiquinone-binding protein(gene name synonym)|uniprotkb:Qpc(gene name synonym)|uniprotkb:Ubiquinol-cytochrome c reductase complex 9.5 kDa protein(gene name synonym)|uniprotkb:Ubiquinol-cytochrome c reductase complex ubiquinone-binding protein QP-C(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Martins et al. (2018)	imex:IM-28469|pubmed:29476059	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26438079|imex:IM-28469-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSRNOG00000016271(gene)|ensembl:ENSRNOT00000023037(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001540"(amyloid-beta binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0010008"(endosome membrane)|go:"GO:0030660"(Golgi-associated vesicle membrane)|go:"GO:0031301"(integral component of organelle membrane)|go:"GO:0042985"(negative regulation of amyloid precursor protein biosynthetic process)|interpro:IPR007084(BRICHOS)|interpro:IPR040145|mint:Q5XIE8|refseq:NP_001006964.1|rgd:620727	refseq:NP_001020305.1|rgd:1562350|ensembl:ENSRNOG00000048174(gene)|ensembl:ENSRNOT00000073964(transcript)|go:"GO:0005739"(mitochondrion)|go:"GO:0005750"(mitochondrial respiratory chain complex III)|go:"GO:0006122"(mitochondrial electron transport, ubiquinol to cytochrome c)|go:"GO:0021539"(subthalamus development)|go:"GO:0021548"(pons development)|go:"GO:0021680"(cerebellar Purkinje cell layer development)|go:"GO:0021766"(hippocampus development)|go:"GO:0021794"(thalamus development)|go:"GO:0021854"(hypothalamus development)|go:"GO:0021860"(pyramidal neuron development)|go:"GO:0030901"(midbrain development)|go:"GO:1902600"(proton transmembrane transport)|interpro:IPR036642|mint:Q7TQ16|reactome:R-RNO-611105|interpro:IPR004205(UcrQ)|refseq:XP_006246378.1	-	-	comment:mint	figure legend:ST1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10116(rat-brain-cerebellum)|taxid:10116(Rattus norvegicus)	-	2020/10/30	2020/10/30	rogid:DtE+ZXAZKdCMvUW5K+jXQ5bH07M10116	rogid:3bMevxh5qeqP+F+G2L+pD+rBK6s10116	rigid:OaXQ9NA25fwCWxejPU3Ao9q5j/E	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q5XIE8	uniprotkb:P62744	intact:EBI-15348306|ensembl:ENSRNOP00000023037	intact:EBI-7617461|uniprotkb:P70626|uniprotkb:Q00380|uniprotkb:P97626|intact:MINT-2514729|ensembl:ENSRNOP00000021310	psi-mi:itm2b_rat(display_long)|uniprotkb:Itm2b(gene name)|psi-mi:Itm2b(display_short)|uniprotkb:Immature BRI2(gene name synonym)|uniprotkb:Transmembrane protein BRI(gene name synonym)	psi-mi:ap2s1_rat(display_long)|uniprotkb:Clathrin assembly protein 2 sigma small chain(gene name synonym)|uniprotkb:Ap2s1(gene name)|psi-mi:Ap2s1(display_short)|uniprotkb:Ap17(gene name synonym)|uniprotkb:Claps2(gene name synonym)|uniprotkb:Adaptor protein complex AP-2 subunit sigma(gene name synonym)|uniprotkb:Sigma2-adaptin(gene name synonym)|uniprotkb:Sigma-adaptin 3b(gene name synonym)|uniprotkb:Plasma membrane adaptor AP-2 17 kDa protein(gene name synonym)|uniprotkb:Clathrin coat assembly protein AP17(gene name synonym)|uniprotkb:Clathrin coat-associated protein AP17(gene name synonym)|uniprotkb:Adaptor-related protein complex 2 subunit sigma(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Martins et al. (2018)	imex:IM-28469|pubmed:29476059	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26438079|imex:IM-28469-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSRNOG00000016271(gene)|ensembl:ENSRNOT00000023037(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001540"(amyloid-beta binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0010008"(endosome membrane)|go:"GO:0030660"(Golgi-associated vesicle membrane)|go:"GO:0031301"(integral component of organelle membrane)|go:"GO:0042985"(negative regulation of amyloid precursor protein biosynthetic process)|interpro:IPR007084(BRICHOS)|interpro:IPR040145|mint:Q5XIE8|refseq:NP_001006964.1|rgd:620727	rgd:620188|refseq:NP_075241.2|ensembl:ENSRNOG00000015865(gene)|ensembl:ENSRNOT00000021310(transcript)|go:"GO:0005886"(plasma membrane)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0016192"(vesicle-mediated transport)|go:"GO:0030122"(AP-2 adaptor complex)|go:"GO:0035615"(clathrin adaptor activity)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0072583"(clathrin-dependent endocytosis)|interpro:IPR000804(Clathrin adaptor, sigma subunit/coatomer, zeta subunit)|interpro:IPR011012(Longin-like)|interpro:IPR016635(Adaptor protein complex, sigma subunit)|interpro:IPR022775|interpro:IPR027156|rcsb pdb:4NEE|rcsb pdb:6OWO|rcsb pdb:6OWT|rcsb pdb:6OXL|reactome:R-RNO-177504|reactome:R-RNO-2132295|reactome:R-RNO-416993|reactome:R-RNO-437239|reactome:R-RNO-5099900|reactome:R-RNO-5140745|reactome:R-RNO-8856825|reactome:R-RNO-8856828|reactome:R-RNO-8866427|reactome:R-RNO-8964038|mint:P62744	-	-	function:Component of the adaptor complexes which link clathrin to receptors in coated vesicles. Clathrin-associated protein complexes are believed to interact with the cytoplasmic tails of membrane proteins, leading to their selection and concentration. AP2S1/AP17 is a subunit of the plasma membrane adaptor. The complex binds polyphosphoinositides|comment:mint	figure legend:ST1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10116(rat-brain-cerebellum)|taxid:10116(Rattus norvegicus)	-	2020/10/30	2020/10/30	rogid:DtE+ZXAZKdCMvUW5K+jXQ5bH07M10116	rogid:AJxHeeoCpwPxjsRcAQkiAGaC9k010116	rigid:OaXQ9NA25fwCWxejPU3Ao9q5j/E	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q5XIE8	uniprotkb:P62944	intact:EBI-15348306|ensembl:ENSRNOP00000023037	intact:EBI-7048246|ensembl:ENSRNOP00000072290|uniprotkb:P21851|intact:MINT-122517	psi-mi:itm2b_rat(display_long)|uniprotkb:Itm2b(gene name)|psi-mi:Itm2b(display_short)|uniprotkb:Immature BRI2(gene name synonym)|uniprotkb:Transmembrane protein BRI(gene name synonym)	psi-mi:ap2b1_rat(display_long)|uniprotkb:Ap2b1(gene name)|psi-mi:Ap2b1(display_short)|uniprotkb:Clapb1(gene name synonym)|uniprotkb:Beta-adaptin(gene name synonym)|uniprotkb:Plasma membrane adaptor HA2/AP2 adaptin beta subunit(gene name synonym)|uniprotkb:Clathrin assembly protein complex 2 beta large chain(gene name synonym)|uniprotkb:AP105B(gene name synonym)|uniprotkb:Adaptor protein complex AP-2 subunit beta(gene name synonym)|uniprotkb:Beta-2-adaptin(gene name synonym)|uniprotkb:Adaptor-related protein complex 2 subunit beta(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Martins et al. (2018)	imex:IM-28469|pubmed:29476059	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26438079|imex:IM-28469-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSRNOG00000016271(gene)|ensembl:ENSRNOT00000023037(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001540"(amyloid-beta binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0010008"(endosome membrane)|go:"GO:0030660"(Golgi-associated vesicle membrane)|go:"GO:0031301"(integral component of organelle membrane)|go:"GO:0042985"(negative regulation of amyloid precursor protein biosynthetic process)|interpro:IPR007084(BRICHOS)|interpro:IPR040145|mint:Q5XIE8|refseq:NP_001006964.1|rgd:620727	refseq:XP_008766157.1|refseq:XP_008766158.1|refseq:XP_008766159.1|refseq:XP_008766160.1|refseq:XP_008766161.1|ensembl:ENSRNOG00000061543(gene)|ensembl:ENSRNOT00000085799(transcript)|go:"GO:0001822"(kidney development)|go:"GO:0003279"(cardiac septum development)|go:"GO:0003281"(ventricular septum development)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0007507"(heart development)|go:"GO:0016192"(vesicle-mediated transport)|go:"GO:0030118"(clathrin coat)|go:"GO:0030119"(AP-type membrane coat adaptor complex)|go:"GO:0030122"(AP-2 adaptor complex)|go:"GO:0030131"(clathrin adaptor complex)|go:"GO:0030276"(clathrin binding)|go:"GO:0035904"(aorta development)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045807"(positive regulation of endocytosis)|go:"GO:0048268"(clathrin coat assembly)|go:"GO:0060976"(coronary vasculature development)|go:"GO:0098794"(postsynapse)|go:"GO:0098884"(postsynaptic neurotransmitter receptor internalization)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099590"(neurotransmitter receptor internalization)|go:"GO:1901215"(negative regulation of neuron death)|go:"GO:1905477"(positive regulation of protein localization to membrane)|interpro:IPR000225(Armadillo)|interpro:IPR002553(Clathrin/coatomer adaptor, adaptin-like, N-terminal)|interpro:IPR008152(Clathrin adaptor, alpha/beta/gamma-adaptin, appendage, Ig-like subdomain)|interpro:IPR009028(Clathrin/coatomer adaptor, adaptin-like, appendage, C-terminal subdomain)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR012295(Beta2-adaptin/TATA-box binding, C-terminal)|interpro:IPR013037(Clathrin adaptor, beta-adaptin, appendage, Ig-like subdomain)|interpro:IPR013041(Clathrin/coatomer adaptor, adaptin-like, appendage, Ig-like subdomain)|interpro:IPR015151(Clathrin adaptor, beta-adaptin, appendage, C-terminal subdomain)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR016342(Adaptor protein complex, beta subunit)|interpro:IPR026739|mint:P62944|rcsb pdb:3H1Z|rcsb pdb:3HS9|rcsb pdb:6OWT|reactome:R-RNO-177504|reactome:R-RNO-2132295|reactome:R-RNO-416993|reactome:R-RNO-437239|reactome:R-RNO-5099900|reactome:R-RNO-5140745|go:"GO:0072583"(clathrin-dependent endocytosis)|reactome:R-RNO-8856825|reactome:R-RNO-8856828|reactome:R-RNO-8866427|reactome:R-RNO-8964038|refseq:XP_017452462.1|refseq:NP_542150.1|rgd:71048|dip:DIP-40944N	-	-	function:Component of the adaptor complexes which link clathrin to receptors in coated vesicles. Clathrin-associated protein complexes are believed to interact with the cytoplasmic tails of membrane proteins, leading to their selection and concentration. AP2B1 is a subunit of the plasma membrane adaptor. The complex binds polyphosphoinositides|comment:mint	figure legend:ST1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10116(rat-brain-cerebellum)|taxid:10116(Rattus norvegicus)	-	2020/10/30	2020/10/30	rogid:DtE+ZXAZKdCMvUW5K+jXQ5bH07M10116	rogid:Q5oFhdE1hcmqu7xLG3MteCu0Zcg10116	rigid:OaXQ9NA25fwCWxejPU3Ao9q5j/E	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q5XIE8	uniprotkb:P63025	intact:EBI-15348306|ensembl:ENSRNOP00000023037	intact:EBI-7705696|ensembl:ENSRNOP00000048364|intact:MINT-4139742|uniprotkb:Q64271	psi-mi:itm2b_rat(display_long)|uniprotkb:Itm2b(gene name)|psi-mi:Itm2b(display_short)|uniprotkb:Immature BRI2(gene name synonym)|uniprotkb:Transmembrane protein BRI(gene name synonym)	psi-mi:vamp3_rat(display_long)|uniprotkb:Vamp3(gene name)|psi-mi:Vamp3(display_short)|uniprotkb:Syb3(gene name synonym)|uniprotkb:Synaptobrevin-3(gene name synonym)|uniprotkb:Cellubrevin(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Martins et al. (2018)	imex:IM-28469|pubmed:29476059	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26438079|imex:IM-28469-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSRNOG00000016271(gene)|ensembl:ENSRNOT00000023037(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001540"(amyloid-beta binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0010008"(endosome membrane)|go:"GO:0030660"(Golgi-associated vesicle membrane)|go:"GO:0031301"(integral component of organelle membrane)|go:"GO:0042985"(negative regulation of amyloid precursor protein biosynthetic process)|interpro:IPR007084(BRICHOS)|interpro:IPR040145|mint:Q5XIE8|refseq:NP_001006964.1|rgd:620727	ensembl:ENSRNOG00000030055(gene)|ensembl:ENSRNOT00000051554(transcript)|go:"GO:0000149"(SNARE binding)|go:"GO:0001921"(positive regulation of receptor recycling)|go:"GO:0005484"(SNAP receptor activity)|go:"GO:0005769"(early endosome)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006906"(vesicle fusion)|go:"GO:0009986"(cell surface)|go:"GO:0016192"(vesicle-mediated transport)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0017075"(syntaxin-1 binding)|go:"GO:0017156"(calcium-ion regulated exocytosis)|go:"GO:0019905"(syntaxin binding)|go:"GO:0030136"(clathrin-coated vesicle)|go:"GO:0030141"(secretory granule)|go:"GO:0030285"(integral component of synaptic vesicle membrane)|go:"GO:0030665"(clathrin-coated vesicle membrane)|go:"GO:0031201"(SNARE complex)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0035493"(SNARE complex assembly)|go:"GO:0042147"(retrograde transport, endosome to Golgi)|go:"GO:0043001"(Golgi to plasma membrane protein transport)|go:"GO:0043005"(neuron projection)|go:"GO:0043229"(intracellular organelle)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0045335"(phagocytic vesicle)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0055037"(recycling endosome)|go:"GO:0065003"(protein-containing complex assembly)|go:"GO:0071346"(cellular response to interferon-gamma)|go:"GO:0097708"(intracellular vesicle)|go:"GO:1903531"(negative regulation of secretion by cell)|interpro:IPR001388(Synaptobrevin)|interpro:IPR016444(Synaptobrevin, metazoa/fungi)|interpro:IPR042855|mint:P63025|rcsb pdb:5KJ7|rcsb pdb:5KJ8|reactome:R-RNO-6811440|reactome:R-RNO-8856825|reactome:R-RNO-8856828|reactome:R-RNO-8980692|reactome:R-RNO-9013026|reactome:R-RNO-9013106|reactome:R-RNO-9013148|reactome:R-RNO-9013149|reactome:R-RNO-9013404|reactome:R-RNO-9013405|reactome:R-RNO-9013406|reactome:R-RNO-9013407|reactome:R-RNO-9013408|reactome:R-RNO-9013423|reactome:R-RNO-9035034|go:"GO:0034446"(substrate adhesion-dependent cell spreading)|refseq:NP_476438.1|rgd:61880	-	-	comment:mint|function:Trafficking protein from a constitutively recycling pathway	figure legend:ST1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10116(rat-brain-cerebellum)|taxid:10116(Rattus norvegicus)	-	2020/10/30	2020/10/30	rogid:DtE+ZXAZKdCMvUW5K+jXQ5bH07M10116	rogid:+bFr3sWwXWDPrsL8ZRrf+4CpLqo10116	rigid:OaXQ9NA25fwCWxejPU3Ao9q5j/E	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q5XIE8	uniprotkb:Q9QYF3	intact:EBI-15348306|ensembl:ENSRNOP00000023037	intact:EBI-7622981|intact:MINT-7138773	psi-mi:itm2b_rat(display_long)|uniprotkb:Itm2b(gene name)|psi-mi:Itm2b(display_short)|uniprotkb:Immature BRI2(gene name synonym)|uniprotkb:Transmembrane protein BRI(gene name synonym)	psi-mi:myo5a_rat(display_long)|uniprotkb:Myo5a(gene name)|psi-mi:Myo5a(display_short)|uniprotkb:Dilute myosin heavy chain, non-muscle(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Martins et al. (2018)	imex:IM-28469|pubmed:29476059	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26438079|imex:IM-28469-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSRNOG00000016271(gene)|ensembl:ENSRNOT00000023037(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001540"(amyloid-beta binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0010008"(endosome membrane)|go:"GO:0030660"(Golgi-associated vesicle membrane)|go:"GO:0031301"(integral component of organelle membrane)|go:"GO:0042985"(negative regulation of amyloid precursor protein biosynthetic process)|interpro:IPR007084(BRICHOS)|interpro:IPR040145|mint:Q5XIE8|refseq:NP_001006964.1|rgd:620727	interpro:IPR004009(Myosin, N-terminal, SH3-like)|mint:Q9QYF3|interpro:IPR037988|interpro:IPR027417|rgd:3143|interpro:IPR001609(Myosin head, motor region)|interpro:IPR002710(Dilute)|refseq:NP_071514.1|interpro:IPR000048(IQ calmodulin-binding region)|go:"GO:0000146"(microfilament motor activity)|go:"GO:0000149"(SNARE binding)|go:"GO:0001726"(ruffle)|go:"GO:0001750"(photoreceptor outer segment)|go:"GO:0003774"(cytoskeletal motor activity)|go:"GO:0003779"(actin binding)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005790"(smooth endoplasmic reticulum)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0005882"(intermediate filament)|go:"GO:0006582"(melanin metabolic process)|go:"GO:0006887"(exocytosis)|go:"GO:0006892"(post-Golgi vesicle-mediated transport)|go:"GO:0007015"(actin filament organization)|go:"GO:0007268"(chemical synaptic transmission)|go:"GO:0007601"(visual perception)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0014046"(dopamine secretion)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0016020"(membrane)|go:"GO:0016192"(vesicle-mediated transport)|go:"GO:0016236"(macroautophagy)|go:"GO:0016459"(myosin complex)|go:"GO:0016461"(unconventional myosin complex)|go:"GO:0017075"(syntaxin-1 binding)|go:"GO:0017157"(regulation of exocytosis)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030048"(actin filament-based movement)|go:"GO:0030050"(vesicle transport along actin filament)|go:"GO:0030073"(insulin secretion)|go:"GO:0030141"(secretory granule)|go:"GO:0030318"(melanocyte differentiation)|go:"GO:0030424"(axon)|go:"GO:0030425"(dendrite)|go:"GO:0031267"(small GTPase binding)|go:"GO:0031585"(regulation of inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity)|go:"GO:0031982"(vesicle)|go:"GO:0031987"(locomotion involved in locomotory behavior)|go:"GO:0032252"(secretory granule localization)|go:"GO:0032400"(melanosome localization)|go:"GO:0032402"(melanosome transport)|go:"GO:0032433"(filopodium tip)|go:"GO:0032593"(insulin-responsive compartment)|go:"GO:0032869"(cellular response to insulin stimulus)|go:"GO:0035249"(synaptic transmission, glutamatergic)|go:"GO:0042417"(dopamine metabolic process)|go:"GO:0042438"(melanin biosynthetic process)|go:"GO:0042470"(melanosome)|go:"GO:0042476"(odontogenesis)|go:"GO:0042552"(myelination)|go:"GO:0042641"(actomyosin)|go:"GO:0042642"(actomyosin, myosin complex part)|go:"GO:0042759"(long-chain fatty acid biosynthetic process)|go:"GO:0042802"(identical protein binding)|go:"GO:0043005"(neuron projection)|go:"GO:0043008"(ATP-dependent protein binding)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043473"(pigmentation)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0048066"(developmental pigmentation)|go:"GO:0048306"(calcium-dependent protein binding)|go:"GO:0048820"(hair follicle maturation)|go:"GO:0050808"(synapse organization)|go:"GO:0050885"(neuromuscular process controlling balance)|go:"GO:0051015"(actin filament binding)|go:"GO:0051643"(endoplasmic reticulum localization)|go:"GO:0055037"(recycling endosome)|go:"GO:0065003"(protein-containing complex assembly)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0097718"(disordered domain specific binding)|go:"GO:0098685"(Schaffer collateral - CA1 synapse)|go:"GO:0098794"(postsynapse)|go:"GO:0098871"(postsynaptic actin cytoskeleton)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099089"(establishment of endoplasmic reticulum localization to postsynapse)|go:"GO:0099566"(regulation of postsynaptic cytosolic calcium ion concentration)|go:"GO:0099640"(axo-dendritic protein transport)|go:"GO:0150103"(reactive gliosis)|go:"GO:1900078"(positive regulation of cellular response to insulin stimulus)|go:"GO:1903078"(positive regulation of protein localization to plasma membrane)|go:"GO:1904754"(positive regulation of vascular associated smooth muscle cell migration)|go:"GO:1904960"(positive regulation of cytochrome-c oxidase activity)|go:"GO:1990904"(ribonucleoprotein complex)|reactome:R-RNO-2029482|interpro:IPR036103	-	-	comment:mint	figure legend:ST1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10116(rat-brain-cerebellum)|taxid:10116(Rattus norvegicus)	-	2020/10/30	2020/10/30	rogid:DtE+ZXAZKdCMvUW5K+jXQ5bH07M10116	rogid:ZQ1JIIcrUKmT1R7vXK9jJ+Ngw0w10116	rigid:OaXQ9NA25fwCWxejPU3Ao9q5j/E	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q5XIE8	uniprotkb:G3V9R8	intact:EBI-15348306|ensembl:ENSRNOP00000023037	intact:EBI-7621160|uniprotkb:D4ACR0|uniprotkb:Q4V8K6|intact:MINT-7138494	psi-mi:itm2b_rat(display_long)|uniprotkb:Itm2b(gene name)|psi-mi:Itm2b(display_short)|uniprotkb:Immature BRI2(gene name synonym)|uniprotkb:Transmembrane protein BRI(gene name synonym)	psi-mi:hnrpc_rat(display_long)|uniprotkb:Hnrpc(gene name synonym)|uniprotkb:hnRNP core protein C(gene name synonym)|uniprotkb:Hnrnpc(gene name)|psi-mi:Hnrnpc(display_short)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Martins et al. (2018)	imex:IM-28469|pubmed:29476059	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26438079|imex:IM-28469-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSRNOG00000016271(gene)|ensembl:ENSRNOT00000023037(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001540"(amyloid-beta binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0010008"(endosome membrane)|go:"GO:0030660"(Golgi-associated vesicle membrane)|go:"GO:0031301"(integral component of organelle membrane)|go:"GO:0042985"(negative regulation of amyloid precursor protein biosynthetic process)|interpro:IPR007084(BRICHOS)|interpro:IPR040145|mint:Q5XIE8|refseq:NP_001006964.1|rgd:620727	interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|mint:G3V9R8|interpro:IPR000504(RNA recognition motif, RNP-1)|rgd:1309982|interpro:IPR017347(Heterogeneous nuclear ribonucleoprotein C, Raly)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0003730"(mRNA 3'-UTR binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0004857"(enzyme inhibitor activity)|go:"GO:0032211"(negative regulation of telomere maintenance via telomerase)|go:"GO:0032991"(protein-containing complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0005634"(nucleus)|go:"GO:0043021"(ribonucleoprotein complex binding)|go:"GO:0045120"(pronucleus)|go:"GO:0070034"(telomerase RNA binding)|go:"GO:0070935"(3'-UTR-mediated mRNA stabilization)|go:"GO:0071013"(catalytic step 2 spliceosome)|go:"GO:0090367"(negative regulation of mRNA modification)|go:"GO:1990247"(N6-methyladenosine-containing RNA binding)|go:"GO:0005681"(spliceosomal complex)|go:"GO:1990826"(nucleoplasmic periphery of the nuclear pore complex)|go:"GO:1990827"(deaminase binding)|reactome:R-RNO-4570464|go:"GO:0005697"(telomerase holoenzyme complex)|reactome:R-RNO-72163|reactome:R-RNO-9013418|reactome:R-RNO-9013422|go:"GO:0005829"(cytosol)|go:"GO:0008266"("poly(U) RNA binding")|go:"GO:0015629"(actin cytoskeleton)|interpro:IPR035979	-	-	comment:mint	figure legend:ST1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10116(rat-brain-cerebellum)|taxid:10116(Rattus norvegicus)	-	2020/10/30	2020/10/30	rogid:DtE+ZXAZKdCMvUW5K+jXQ5bH07M10116	rogid:cgiYueABuKLkNADHbWll/dynlLo10116	rigid:OaXQ9NA25fwCWxejPU3Ao9q5j/E	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q5XIE8	uniprotkb:P59215	intact:EBI-15348306|ensembl:ENSRNOP00000023037	intact:EBI-8071125|intact:MINT-5028451|uniprotkb:P04900|intact:MINT-6380317|uniprotkb:P30033|ensembl:ENSRNOP00000026373	psi-mi:itm2b_rat(display_long)|uniprotkb:Itm2b(gene name)|psi-mi:Itm2b(display_short)|uniprotkb:Immature BRI2(gene name synonym)|uniprotkb:Transmembrane protein BRI(gene name synonym)	psi-mi:gnao_rat(display_long)|uniprotkb:Gnao1(gene name)|psi-mi:Gnao1(display_short)|uniprotkb:Gna0(gene name synonym)|uniprotkb:Gnao(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Martins et al. (2018)	imex:IM-28469|pubmed:29476059	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26438079|imex:IM-28469-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSRNOG00000016271(gene)|ensembl:ENSRNOT00000023037(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001540"(amyloid-beta binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0010008"(endosome membrane)|go:"GO:0030660"(Golgi-associated vesicle membrane)|go:"GO:0031301"(integral component of organelle membrane)|go:"GO:0042985"(negative regulation of amyloid precursor protein biosynthetic process)|interpro:IPR007084(BRICHOS)|interpro:IPR040145|mint:Q5XIE8|refseq:NP_001006964.1|rgd:620727	rgd:628732|refseq:NP_059023.1|dip:DIP-59090N|ensembl:ENSRNOG00000019482(gene)|ensembl:ENSRNOT00000026373(transcript)|go:"GO:0001664"(G protein-coupled receptor binding)|go:"GO:0003924"(GTPase activity)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005525"(GTP binding)|go:"GO:0005834"(heterotrimeric G-protein complex)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0007188"(adenylate cyclase-modulating G protein-coupled receptor signaling pathway)|go:"GO:0007212"(dopamine receptor signaling pathway)|go:"GO:0007568"(aging)|go:"GO:0007626"(locomotory behavior)|go:"GO:0008016"(regulation of heart contraction)|go:"GO:0009987"(cellular process)|go:"GO:0014070"(response to organic cyclic compound)|go:"GO:0016020"(membrane)|go:"GO:0019003"(GDP binding)|go:"GO:0030425"(dendrite)|go:"GO:0030900"(forebrain development)|go:"GO:0031175"(neuron projection development)|go:"GO:0031683"(G-protein beta/gamma-subunit complex binding)|go:"GO:0031821"(G protein-coupled serotonin receptor binding)|go:"GO:0031852"(mu-type opioid receptor binding)|go:"GO:0032794"(GTPase activating protein binding)|go:"GO:0034097"(response to cytokine)|go:"GO:0042475"(odontogenesis of dentin-containing tooth)|go:"GO:0042493"|go:"GO:0042542"(response to hydrogen peroxide)|go:"GO:0043005"(neuron projection)|go:"GO:0043209"(myelin sheath)|go:"GO:0043278"(response to morphine)|go:"GO:0043547"(positive regulation of GTPase activity)|go:"GO:0044297"(cell body)|go:"GO:0046872"(metal ion binding)|go:"GO:0051430"(corticotropin-releasing hormone receptor 1 binding)|go:"GO:0051926"(negative regulation of calcium ion transport)|interpro:IPR001019("Guanine nucleotide binding protein (G-protein), alpha subunit")|interpro:IPR001408(G-protein alpha subunit, group I)|interpro:IPR011025(G protein alpha subunit, helical insertion)|interpro:IPR027417|mint:P59215|reactome:R-RNO-4086398|go:"GO:0010243"(response to organonitrogen compound)	-	-	comment:mint|function:"Guanine nucleotide-binding proteins (G proteins) are involved as modulators or transducers in various transmembrane signaling systems. The G(o) protein function is not clear"|comment:homomint	figure legend:ST1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10116(rat-brain-cerebellum)|taxid:10116(Rattus norvegicus)	-	2020/10/30	2020/10/30	rogid:DtE+ZXAZKdCMvUW5K+jXQ5bH07M10116	rogid:LuKGAVyaFxWTp6ctQzokHhwyo3410116	rigid:OaXQ9NA25fwCWxejPU3Ao9q5j/E	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q5XIE8	uniprotkb:Q71RJ2	intact:EBI-15348306|ensembl:ENSRNOP00000023037	intact:EBI-8538384|intact:MINT-1784279|ensembl:ENSRNOP00000008414	psi-mi:itm2b_rat(display_long)|uniprotkb:Itm2b(gene name)|psi-mi:Itm2b(display_short)|uniprotkb:Immature BRI2(gene name synonym)|uniprotkb:Transmembrane protein BRI(gene name synonym)	psi-mi:ccg2_rat(display_long)|uniprotkb:Cacng2(gene name)|psi-mi:Cacng2(display_short)|uniprotkb:Neuronal voltage-gated calcium channel gamma-2 subunit(gene name synonym)|uniprotkb:Transmembrane AMPAR regulatory protein gamma-2(gene name synonym)|uniprotkb:Stargazin(gene name synonym)|uniprotkb:Stg(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Martins et al. (2018)	imex:IM-28469|pubmed:29476059	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26438079|imex:IM-28469-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSRNOG00000016271(gene)|ensembl:ENSRNOT00000023037(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001540"(amyloid-beta binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0010008"(endosome membrane)|go:"GO:0030660"(Golgi-associated vesicle membrane)|go:"GO:0031301"(integral component of organelle membrane)|go:"GO:0042985"(negative regulation of amyloid precursor protein biosynthetic process)|interpro:IPR007084(BRICHOS)|interpro:IPR040145|mint:Q5XIE8|refseq:NP_001006964.1|rgd:620727	refseq:NP_445803.1|rgd:71095|dip:DIP-41720N|ensembl:ENSRNOG00000006226(gene)|ensembl:ENSRNOT00000008414(transcript)|go:"GO:0005245"(voltage-gated calcium channel activity)|go:"GO:0005246"(calcium channel regulator activity)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005891"(voltage-gated calcium channel complex)|go:"GO:0006612"(protein targeting to membrane)|go:"GO:0007528"(neuromuscular junction development)|go:"GO:0009986"(cell surface)|go:"GO:0014069"(postsynaptic density)|go:"GO:0016247"(channel regulator activity)|go:"GO:0019226"(transmission of nerve impulse)|go:"GO:0032281"(AMPA glutamate receptor complex)|go:"GO:0035255"(ionotropic glutamate receptor binding)|go:"GO:0036477"(somatodendritic compartment)|go:"GO:0042391"(regulation of membrane potential)|go:"GO:0044300"(cerebellar mossy fiber)|go:"GO:0050877"(nervous system process)|go:"GO:0051592"(response to calcium ion)|go:"GO:0051899"(membrane depolarization)|go:"GO:0051968"(positive regulation of synaptic transmission, glutamatergic)|go:"GO:0060081"(membrane hyperpolarization)|go:"GO:0060082"(eye blink reflex)|go:"GO:0098685"(Schaffer collateral - CA1 synapse)|go:"GO:0098686"(hippocampal mossy fiber to CA3 synapse)|go:"GO:0098839"(postsynaptic density membrane)|go:"GO:0098943"(neurotransmitter receptor transport, postsynaptic endosome to lysosome)|go:"GO:0098970"(postsynaptic neurotransmitter receptor diffusion trapping)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099061"(integral component of postsynaptic density membrane)|go:"GO:0099072"(regulation of postsynaptic membrane neurotransmitter receptor levels)|go:"GO:0099590"(neurotransmitter receptor internalization)|go:"GO:0099645"(neurotransmitter receptor localization to postsynaptic specialization membrane)|go:"GO:1904510"(positive regulation of protein localization to basolateral plasma membrane)|go:"GO:2000311"(regulation of AMPA receptor activity)|go:"GO:2000969"(positive regulation of AMPA receptor activity)|interpro:IPR004031(PMP-22/EMP/MP20/Claudin)|interpro:IPR005422(Voltage-dependent calcium channel, gamma-2 subunit)|interpro:IPR008368(Voltage-dependent calcium channel, gamma subunit)|mint:Q71RJ2|rcsb pdb:5KK2|rcsb pdb:5VOT|rcsb pdb:5VOU|rcsb pdb:5VOV|rcsb pdb:6NJL|rcsb pdb:6NJM|rcsb pdb:6NJN|reactome:R-RNO-112308|reactome:R-RNO-399719|reactome:R-RNO-5682910	-	-	comment:mint	figure legend:ST1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10116(rat-brain-cerebellum)|taxid:10116(Rattus norvegicus)	-	2020/10/30	2020/10/30	rogid:DtE+ZXAZKdCMvUW5K+jXQ5bH07M10116	rogid:horuxO013U9eKJYCTV7fS8OC0BY10116	rigid:OaXQ9NA25fwCWxejPU3Ao9q5j/E	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q5XIE8	uniprotkb:Q6AY56	intact:EBI-15348306|ensembl:ENSRNOP00000023037	intact:EBI-7626417|intact:MINT-7139102|ensembl:ENSRNOP00000065108	psi-mi:itm2b_rat(display_long)|uniprotkb:Itm2b(gene name)|psi-mi:Itm2b(display_short)|uniprotkb:Immature BRI2(gene name synonym)|uniprotkb:Transmembrane protein BRI(gene name synonym)	psi-mi:tba8_rat(display_long)|uniprotkb:Tuba8(gene name)|psi-mi:Tuba8(display_short)|uniprotkb:Alpha-tubulin 8(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Martins et al. (2018)	imex:IM-28469|pubmed:29476059	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26438079|imex:IM-28469-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSRNOG00000016271(gene)|ensembl:ENSRNOT00000023037(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001540"(amyloid-beta binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0010008"(endosome membrane)|go:"GO:0030660"(Golgi-associated vesicle membrane)|go:"GO:0031301"(integral component of organelle membrane)|go:"GO:0042985"(negative regulation of amyloid precursor protein biosynthetic process)|interpro:IPR007084(BRICHOS)|interpro:IPR040145|mint:Q5XIE8|refseq:NP_001006964.1|rgd:620727	refseq:NP_001019510.1|rgd:1566041|ensembl:ENSRNOG00000048169(gene)|ensembl:ENSRNOT00000074096(transcript)|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0005200"(structural constituent of cytoskeleton)|go:"GO:0005525"(GTP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005874"(microtubule)|interpro:IPR000217(Tubulin)|interpro:IPR002452(Alpha tubulin)|interpro:IPR003008(Tubulin/FtsZ, GTPase)|interpro:IPR008280(Tubulin/FtsZ, C-terminal)|interpro:IPR017975|interpro:IPR018316|interpro:IPR023123|interpro:IPR036525|interpro:IPR037103|mint:Q6AY56|reactome:R-RNO-190840|reactome:R-RNO-2132295|reactome:R-RNO-2467813|reactome:R-RNO-2500257|reactome:R-RNO-3371497|reactome:R-RNO-380320|reactome:R-RNO-437239|reactome:R-RNO-5617833|reactome:R-RNO-5626467|reactome:R-RNO-5663220|reactome:R-RNO-6807878|reactome:R-RNO-6811434|reactome:R-RNO-6811436|reactome:R-RNO-68877|reactome:R-RNO-8852276|reactome:R-RNO-8955332|reactome:R-RNO-9646399|reactome:R-RNO-9648025|reactome:R-RNO-9668328|reactome:R-RNO-983189	-	-	comment:mint	figure legend:ST1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10116(rat-brain-cerebellum)|taxid:10116(Rattus norvegicus)	-	2020/10/30	2020/10/30	rogid:DtE+ZXAZKdCMvUW5K+jXQ5bH07M10116	rogid:rrX3LFrXmTyeMg5Fud7c00e0jHE10116	rigid:OaXQ9NA25fwCWxejPU3Ao9q5j/E	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q5XIE8	uniprotkb:Q6AYT3	intact:EBI-15348306|ensembl:ENSRNOP00000023037	intact:EBI-7622129|intact:MINT-4576391|uniprotkb:Q6PX76|ensembl:ENSRNOP00000006570	psi-mi:itm2b_rat(display_long)|uniprotkb:Itm2b(gene name)|psi-mi:Itm2b(display_short)|uniprotkb:Immature BRI2(gene name synonym)|uniprotkb:Transmembrane protein BRI(gene name synonym)	psi-mi:rtcb_rat(display_long)|uniprotkb:Rtcb(gene name)|psi-mi:Rtcb(display_short)|uniprotkb:p55(gene name synonym)|uniprotkb:3'-phosphate/5'-hydroxy nucleic acid ligase(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Martins et al. (2018)	imex:IM-28469|pubmed:29476059	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26438079|imex:IM-28469-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSRNOG00000016271(gene)|ensembl:ENSRNOT00000023037(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001540"(amyloid-beta binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0010008"(endosome membrane)|go:"GO:0030660"(Golgi-associated vesicle membrane)|go:"GO:0031301"(integral component of organelle membrane)|go:"GO:0042985"(negative regulation of amyloid precursor protein biosynthetic process)|interpro:IPR007084(BRICHOS)|interpro:IPR040145|mint:Q5XIE8|refseq:NP_001006964.1|rgd:620727	refseq:NP_997497.1|rgd:1303261|ensembl:ENSRNOG00000004813(gene)|ensembl:ENSRNOT00000006570(transcript)|go:"GO:0000971"(tRNA exon ligation utilizing 2',3' cyclic phosphate of 5'-exon as source of linkage phosphate)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0001890"(placenta development)|go:"GO:0003972"("RNA ligase (ATP) activity")|go:"GO:0005525"(GTP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005829"(cytosol)|go:"GO:0006388"(tRNA splicing, via endonucleolytic cleavage and ligation)|go:"GO:0017166"(vinculin binding)|go:"GO:0046872"(metal ion binding)|go:"GO:0072669"(tRNA-splicing ligase complex)|interpro:IPR001233(Protein of unknown function UPF0027)|interpro:IPR027513|interpro:IPR036025|mint:Q6AYT3	-	-	comment:mint	figure legend:ST1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10116(rat-brain-cerebellum)|taxid:10116(Rattus norvegicus)	-	2020/10/30	2020/10/30	rogid:DtE+ZXAZKdCMvUW5K+jXQ5bH07M10116	rogid:ISQNiLQA7DCcgBkTueMDhUHrkFQ10116	rigid:OaXQ9NA25fwCWxejPU3Ao9q5j/E	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q5XIE8	uniprotkb:P16290	intact:EBI-15348306|ensembl:ENSRNOP00000023037	intact:EBI-6998172|ensembl:ENSRNOP00000018227|intact:MINT-4588391	psi-mi:itm2b_rat(display_long)|uniprotkb:Itm2b(gene name)|psi-mi:Itm2b(display_short)|uniprotkb:Immature BRI2(gene name synonym)|uniprotkb:Transmembrane protein BRI(gene name synonym)	psi-mi:pgam2_rat(display_long)|uniprotkb:Pgam2(gene name)|psi-mi:Pgam2(display_short)|uniprotkb:BPG-dependent PGAM 2(gene name synonym)|uniprotkb:Muscle-specific phosphoglycerate mutase(gene name synonym)|uniprotkb:Phosphoglycerate mutase isozyme M(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Martins et al. (2018)	imex:IM-28469|pubmed:29476059	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26438079|imex:IM-28469-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSRNOG00000016271(gene)|ensembl:ENSRNOT00000023037(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001540"(amyloid-beta binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0010008"(endosome membrane)|go:"GO:0030660"(Golgi-associated vesicle membrane)|go:"GO:0031301"(integral component of organelle membrane)|go:"GO:0042985"(negative regulation of amyloid precursor protein biosynthetic process)|interpro:IPR007084(BRICHOS)|interpro:IPR040145|mint:Q5XIE8|refseq:NP_001006964.1|rgd:620727	ensembl:ENSRNOG00000013532(gene)|ensembl:ENSRNOT00000018227(transcript)|go:"GO:0004082"(bisphosphoglycerate mutase activity)|go:"GO:0004619"(phosphoglycerate mutase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0006094"(gluconeogenesis)|go:"GO:0006096"(glycolytic process)|go:"GO:0006941"(striated muscle contraction)|go:"GO:0007219"(Notch signaling pathway)|go:"GO:0007283"(spermatogenesis)|go:"GO:0010035"(response to inorganic substance)|go:"GO:0016787"(hydrolase activity)|go:"GO:0042802"(identical protein binding)|go:"GO:0046538"(2,3-bisphosphoglycerate-dependent phosphoglycerate mutase activity)|go:"GO:0046689"(response to mercury ion)|interpro:IPR001345(Phosphoglycerate/bisphosphoglycerate mutase)|interpro:IPR005952(Phosphoglycerate mutase 1)|interpro:IPR013078(Phosphoglycerate mutase)|interpro:IPR029033|mint:P16290|reactome:R-RNO-70171|reactome:R-RNO-70263|rgd:3313|refseq:NP_059024.1	-	-	function:"Interconversion of 3- and 2-phosphoglycerate with 2,3-bisphosphoglycerate as the primer of the reaction. Can also catalyze the reaction of EC 5.4.2.4 (synthase) and EC 3.1.3.13 (phosphatase), but with a reduced activity"|comment:mint	figure legend:ST1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10116(rat-brain-cerebellum)|taxid:10116(Rattus norvegicus)	-	2020/10/30	2020/10/30	rogid:DtE+ZXAZKdCMvUW5K+jXQ5bH07M10116	rogid:fhgWfnzD+gwvVuHtGvTu7sRxV5410116	rigid:OaXQ9NA25fwCWxejPU3Ao9q5j/E	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q5XIE8	uniprotkb:P08460	intact:EBI-15348306|ensembl:ENSRNOP00000023037	intact:EBI-8280787|intact:MINT-1892021|uniprotkb:Q712L9	psi-mi:itm2b_rat(display_long)|uniprotkb:Itm2b(gene name)|psi-mi:Itm2b(display_short)|uniprotkb:Immature BRI2(gene name synonym)|uniprotkb:Transmembrane protein BRI(gene name synonym)	psi-mi:nid1_rat(display_long)|uniprotkb:Nid1(gene name)|psi-mi:Nid1(display_short)|uniprotkb:Nid(gene name synonym)|uniprotkb:Entactin(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Martins et al. (2018)	imex:IM-28469|pubmed:29476059	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26438079|imex:IM-28469-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSRNOG00000016271(gene)|ensembl:ENSRNOT00000023037(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001540"(amyloid-beta binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0010008"(endosome membrane)|go:"GO:0030660"(Golgi-associated vesicle membrane)|go:"GO:0031301"(integral component of organelle membrane)|go:"GO:0042985"(negative regulation of amyloid precursor protein biosynthetic process)|interpro:IPR007084(BRICHOS)|interpro:IPR040145|mint:Q5XIE8|refseq:NP_001006964.1|rgd:620727	rgd:3178|mint:P08460|interpro:IPR003886(Nidogen, extracellular region)|go:"GO:0005518"(collagen binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005604"(basement membrane)|go:"GO:0005886"(plasma membrane)|go:"GO:0007160"(cell-matrix adhesion)|go:"GO:0010811"(positive regulation of cell-substrate adhesion)|go:"GO:0030198"(extracellular matrix organization)|go:"GO:0031012"(extracellular matrix)|go:"GO:0032836"(glomerular basement membrane development)|go:"GO:0043236"(laminin binding)|go:"GO:0043237"(laminin-1 binding)|go:"GO:0043394"(proteoglycan binding)|go:"GO:0050840"(extracellular matrix binding)|go:"GO:0071944"(cell periphery)	-	-	comment:"fragmentation type: fragment"|comment:mint|function:Sulfated glycoprotein widely distributed in basement membranes and tightly associated with laminin. Also binds to collagen IV and perlecan. It probably has a role in cell-extracellular matrix interactions	figure legend:ST1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10116(rat-brain-cerebellum)|taxid:10116(Rattus norvegicus)	-	2020/10/30	2020/10/30	rogid:DtE+ZXAZKdCMvUW5K+jXQ5bH07M10116	rogid:ygeRqx2WpMEVCIXYHoK30CrfyOg10116	rigid:OaXQ9NA25fwCWxejPU3Ao9q5j/E	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q5XIE8	uniprotkb:P29994	intact:EBI-15348306|ensembl:ENSRNOP00000023037	intact:EBI-8614640|intact:MINT-5026585|uniprotkb:Q62869	psi-mi:itm2b_rat(display_long)|uniprotkb:Itm2b(gene name)|psi-mi:Itm2b(display_short)|uniprotkb:Immature BRI2(gene name synonym)|uniprotkb:Transmembrane protein BRI(gene name synonym)	psi-mi:itpr1_rat(display_long)|uniprotkb:Itpr1(gene name)|psi-mi:Itpr1(display_short)|uniprotkb:Insp3r(gene name synonym)|uniprotkb:Type 1 inositol 1,4,5-trisphosphate receptor(gene name synonym)|uniprotkb:IP3 receptor isoform 1(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Martins et al. (2018)	imex:IM-28469|pubmed:29476059	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26438079|imex:IM-28469-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSRNOG00000016271(gene)|ensembl:ENSRNOT00000023037(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001540"(amyloid-beta binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0010008"(endosome membrane)|go:"GO:0030660"(Golgi-associated vesicle membrane)|go:"GO:0031301"(integral component of organelle membrane)|go:"GO:0042985"(negative regulation of amyloid precursor protein biosynthetic process)|interpro:IPR007084(BRICHOS)|interpro:IPR040145|mint:Q5XIE8|refseq:NP_001006964.1|rgd:620727	go:"GO:0001666"(response to hypoxia)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005637"(nuclear inner membrane)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005886"(plasma membrane)|go:"GO:0005955"(calcineurin complex)|go:"GO:0006816"(calcium ion transport)|go:"GO:0007204"(positive regulation of cytosolic calcium ion concentration)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0009791"(post-embryonic development)|go:"GO:0010976"(positive regulation of neuron projection development)|go:"GO:0014069"(postsynaptic density)|go:"GO:0015278"(calcium-release channel activity)|go:"GO:0005220"(inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity)|go:"GO:0016358"(dendrite development)|go:"GO:0016529"(sarcoplasmic reticulum)|go:"GO:0019903"(protein phosphatase binding)|go:"GO:0030176"(integral component of endoplasmic reticulum membrane)|go:"GO:0030425"(dendrite)|go:"GO:0030658"(transport vesicle membrane)|go:"GO:0030659"(cytoplasmic vesicle membrane)|go:"GO:0030667"(secretory granule membrane)|go:"GO:0030868"(smooth endoplasmic reticulum membrane)|go:"GO:0031088"(platelet dense granule membrane)|go:"GO:0031094"(platelet dense tubular network)|go:"GO:0032469"(endoplasmic reticulum calcium ion homeostasis)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035091"(phosphatidylinositol binding)|go:"GO:0042045"(epithelial fluid transport)|go:"GO:0042802"(identical protein binding)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0019855"(calcium channel inhibitor activity)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045121"(membrane raft)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0050849"(negative regulation of calcium-mediated signaling)|go:"GO:0050882"(voluntary musculoskeletal movement)|go:"GO:0051209"(release of sequestered calcium ion into cytosol)|go:"GO:0051928"(positive regulation of calcium ion transport)|go:"GO:0070059"(intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress)|go:"GO:0070679"(inositol 1,4,5 trisphosphate binding)|go:"GO:0071320"(cellular response to cAMP)|go:"GO:0071456"(cellular response to hypoxia)|go:"GO:0097060"(synaptic membrane)|go:"GO:0097421"(liver regeneration)|go:"GO:0098685"(Schaffer collateral - CA1 synapse)|go:"GO:0098695"(inositol 1,4,5-trisphosphate receptor activity involved in regulation of postsynaptic cytosolic calcium levels)|go:"GO:0098793"(presynapse)|go:"GO:0098794"(postsynapse)|go:"GO:0098982"(GABA-ergic synapse)|go:"GO:1901215"(negative regulation of neuron death)|go:"GO:0044325"(transmembrane transporter binding)|interpro:IPR000493(Inositol 1,4,5-trisphosphate-binding protein receptor)|interpro:IPR000699(Intracellular calcium-release channel)|interpro:IPR005821(Ion transport)|interpro:IPR013662(RyR and IP3R Homology associated)|interpro:IPR014821(Inositol 1,4,5-trisphosphate/ryanodine receptor)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR016093(MIR motif)|interpro:IPR035910|interpro:IPR036300|rcsb pdb:3JAV|rcsb pdb:3T8S|rcsb pdb:3UJ0|rcsb pdb:3UJ4|rcsb pdb:6MU1|rcsb pdb:6MU2|rcsb pdb:7LHE|rcsb pdb:7LHF|reactome:R-RNO-114508|reactome:R-RNO-139853|reactome:R-RNO-381676|reactome:R-RNO-418457|reactome:R-RNO-5578775|reactome:R-RNO-983695|go:"GO:2000347"(positive regulation of hepatocyte proliferation)|refseq:NP_001257526.1|rgd:2933|mint:P29994|dip:DIP-29715N	-	-	comment:mint|function:Intracellular channel that mediates calcium release from the endoplasmic reticulum following stimulation by inositol 1,4,5-trisphosphate	figure legend:ST1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10116(rat-brain-cerebellum)|taxid:10116(Rattus norvegicus)	-	2020/10/30	2020/10/30	rogid:DtE+ZXAZKdCMvUW5K+jXQ5bH07M10116	rogid:L1I4Symxn2ABLg8esgd/caebF5810116	rigid:OaXQ9NA25fwCWxejPU3Ao9q5j/E	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q5XIE8	uniprotkb:O88600	intact:EBI-15348306|ensembl:ENSRNOP00000023037	intact:EBI-7621473|intact:MINT-4566747	psi-mi:itm2b_rat(display_long)|uniprotkb:Itm2b(gene name)|psi-mi:Itm2b(display_short)|uniprotkb:Immature BRI2(gene name synonym)|uniprotkb:Transmembrane protein BRI(gene name synonym)	psi-mi:hsp74_rat(display_long)|uniprotkb:Hspa4(gene name)|psi-mi:Hspa4(display_short)|uniprotkb:Irp94(gene name synonym)|uniprotkb:Ischemia responsive 94 kDa protein(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Martins et al. (2018)	imex:IM-28469|pubmed:29476059	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26438079|imex:IM-28469-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSRNOG00000016271(gene)|ensembl:ENSRNOT00000023037(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001540"(amyloid-beta binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0010008"(endosome membrane)|go:"GO:0030660"(Golgi-associated vesicle membrane)|go:"GO:0031301"(integral component of organelle membrane)|go:"GO:0042985"(negative regulation of amyloid precursor protein biosynthetic process)|interpro:IPR007084(BRICHOS)|interpro:IPR040145|mint:Q5XIE8|refseq:NP_001006964.1|rgd:620727	interpro:IPR013126(Heat shock protein 70)|mint:O88600|interpro:IPR018181|refseq:NP_705893.1|rgd:628878|interpro:IPR029047|interpro:IPR029048|go:"GO:0001822"(kidney development)|go:"GO:0001933"(negative regulation of protein phosphorylation)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005811"(lipid droplet)|go:"GO:0005829"(cytosol)|go:"GO:0009408"(response to heat)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0032092"(positive regulation of protein binding)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043392"(negative regulation of DNA binding)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045040"(protein insertion into mitochondrial outer membrane)|go:"GO:0045766"(positive regulation of angiogenesis)|go:"GO:0051131"(chaperone-mediated protein complex assembly)|go:"GO:0060548"(negative regulation of cell death)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:0070062"(extracellular exosome)|reactome:R-RNO-3371453|interpro:IPR042052|interpro:IPR043129	-	-	comment:mint	figure legend:ST1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10116(rat-brain-cerebellum)|taxid:10116(Rattus norvegicus)	-	2020/10/30	2020/10/30	rogid:DtE+ZXAZKdCMvUW5K+jXQ5bH07M10116	rogid:QZWIA0YUTliNcy+NQOZ7C9UXVlk10116	rigid:OaXQ9NA25fwCWxejPU3Ao9q5j/E	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q5XIE8	uniprotkb:Q63226	intact:EBI-15348306|ensembl:ENSRNOP00000023037	intact:EBI-6988699|intact:MINT-350054|uniprotkb:Q62641	psi-mi:itm2b_rat(display_long)|uniprotkb:Itm2b(gene name)|psi-mi:Itm2b(display_short)|uniprotkb:Immature BRI2(gene name synonym)|uniprotkb:Transmembrane protein BRI(gene name synonym)	psi-mi:grid2_rat(display_long)|uniprotkb:Grid2(gene name)|psi-mi:Grid2(display_short)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Martins et al. (2018)	imex:IM-28469|pubmed:29476059	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26438079|imex:IM-28469-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSRNOG00000016271(gene)|ensembl:ENSRNOT00000023037(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001540"(amyloid-beta binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0010008"(endosome membrane)|go:"GO:0030660"(Golgi-associated vesicle membrane)|go:"GO:0031301"(integral component of organelle membrane)|go:"GO:0042985"(negative regulation of amyloid precursor protein biosynthetic process)|interpro:IPR007084(BRICHOS)|interpro:IPR040145|mint:Q5XIE8|refseq:NP_001006964.1|rgd:620727	go:"GO:0004970"(ionotropic glutamate receptor activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0007157"(heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules)|go:"GO:0008066"(glutamate receptor activity)|go:"GO:0008328"(ionotropic glutamate receptor complex)|go:"GO:0010975"(regulation of neuron projection development)|go:"GO:0014069"(postsynaptic density)|go:"GO:0015276"(ligand-gated ion channel activity)|go:"GO:0016020"(membrane)|go:"GO:0021707"(cerebellar granule cell differentiation)|go:"GO:0030165"(PDZ domain binding)|go:"GO:0034613"(cellular protein localization)|go:"GO:0035249"(synaptic transmission, glutamatergic)|go:"GO:0036477"(somatodendritic compartment)|go:"GO:0038023"(signaling receptor activity)|go:"GO:0042802"(identical protein binding)|go:"GO:0043197"(dendritic spine)|go:"GO:0043523"(regulation of neuron apoptotic process)|go:"GO:0045202"(synapse)|go:"GO:0045211"(postsynaptic membrane)|go:"GO:0050804"(modulation of chemical synaptic transmission)|go:"GO:0051965"(positive regulation of synapse assembly)|go:"GO:0060079"(excitatory postsynaptic potential)|go:"GO:0060134"(prepulse inhibition)|go:"GO:0097110"(scaffold protein binding)|go:"GO:0098688"(parallel fiber to Purkinje cell synapse)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099061"(integral component of postsynaptic density membrane)|go:"GO:0099151"(regulation of postsynaptic density assembly)|go:"GO:1900454"(positive regulation of long-term synaptic depression)|go:"GO:1904315"(transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential)|go:"GO:1904861"(excitatory synapse assembly)|go:"GO:1905606"(regulation of presynapse assembly)|interpro:IPR001320(Ionotropic glutamate receptor)|interpro:IPR001508(NMDA receptor)|interpro:IPR001828(Extracellular ligand-binding receptor)|interpro:IPR019594|interpro:IPR028082|rcsb pdb:2V3T|rcsb pdb:2V3U|rcsb pdb:5CC2|rcsb pdb:5L2E|rcsb pdb:6LU9|rgd:68368|refseq:NP_077355.1|mint:Q63226|dip:DIP-40709N	-	-	comment:mint|function:Receptor for glutamate. L-glutamate acts as an excitatory neurotransmitter at many synapses in the central nervous system. The postsynaptic actions of Glu are mediated by a variety of receptors that are named according to their selective agonists	figure legend:ST1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10116(rat-brain-cerebellum)|taxid:10116(Rattus norvegicus)	-	2020/10/30	2020/10/30	rogid:DtE+ZXAZKdCMvUW5K+jXQ5bH07M10116	rogid:4jogOAk+t1SY2gVH3Hr9pdJy0pM10116	rigid:OaXQ9NA25fwCWxejPU3Ao9q5j/E	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q5XIE8	uniprotkb:Q68FR6	intact:EBI-15348306|ensembl:ENSRNOP00000023037	intact:EBI-7619783|uniprotkb:Q4FZZ5|intact:UNK-5423025|ensembl:ENSRNOP00000027305	psi-mi:itm2b_rat(display_long)|uniprotkb:Itm2b(gene name)|psi-mi:Itm2b(display_short)|uniprotkb:Immature BRI2(gene name synonym)|uniprotkb:Transmembrane protein BRI(gene name synonym)	psi-mi:ef1g_rat(display_long)|uniprotkb:Eef1g(gene name)|psi-mi:Eef1g(display_short)|uniprotkb:eEF-1B gamma(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Martins et al. (2018)	imex:IM-28469|pubmed:29476059	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26438079|imex:IM-28469-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSRNOG00000016271(gene)|ensembl:ENSRNOT00000023037(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001540"(amyloid-beta binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0010008"(endosome membrane)|go:"GO:0030660"(Golgi-associated vesicle membrane)|go:"GO:0031301"(integral component of organelle membrane)|go:"GO:0042985"(negative regulation of amyloid precursor protein biosynthetic process)|interpro:IPR007084(BRICHOS)|interpro:IPR040145|mint:Q5XIE8|refseq:NP_001006964.1|rgd:620727	refseq:NP_001004223.1|rgd:1302939|ensembl:ENSRNOG00000020075(gene)|ensembl:ENSRNOT00000027305(transcript)|go:"GO:0003746"(translation elongation factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0006414"(translational elongation)|go:"GO:0006749"(glutathione metabolic process)|go:"GO:0009615"(response to virus)|interpro:IPR001662(Translation elongation factor EF1B, gamma chain, conserved)|interpro:IPR004045(Glutathione S-transferase, N-terminal)|interpro:IPR004046(Glutathione S-transferase, C-terminal)|interpro:IPR010987(Glutathione S-transferase, C-terminal-like)|interpro:IPR036249|interpro:IPR036282|interpro:IPR036433|interpro:IPR040079|mint:Q68FR6|reactome:R-RNO-156842	-	-	function:Probably plays a role in anchoring the complex to other cellular components|comment:mint	figure legend:ST1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10116(rat-brain-cerebellum)|taxid:10116(Rattus norvegicus)	-	2020/10/30	2020/10/30	rogid:DtE+ZXAZKdCMvUW5K+jXQ5bH07M10116	rogid:sKEqpV//My1v5Sie5iosXfmxmvg10116	rigid:OaXQ9NA25fwCWxejPU3Ao9q5j/E	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q5XIE8	uniprotkb:Q4V7C7	intact:EBI-15348306|ensembl:ENSRNOP00000023037	intact:EBI-6986503|ensembl:ENSRNOP00000004520|intact:MINT-4579360|uniprotkb:A9CM89|uniprotkb:A9CM90|intact:MINT-3376858	psi-mi:itm2b_rat(display_long)|uniprotkb:Itm2b(gene name)|psi-mi:Itm2b(display_short)|uniprotkb:Immature BRI2(gene name synonym)|uniprotkb:Transmembrane protein BRI(gene name synonym)	psi-mi:arp3_rat(display_long)|uniprotkb:Actr3(gene name)|psi-mi:Actr3(display_short)|uniprotkb:Arp3(gene name synonym)|uniprotkb:Actin-like protein 3(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Martins et al. (2018)	imex:IM-28469|pubmed:29476059	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26438079|imex:IM-28469-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSRNOG00000016271(gene)|ensembl:ENSRNOT00000023037(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001540"(amyloid-beta binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0010008"(endosome membrane)|go:"GO:0030660"(Golgi-associated vesicle membrane)|go:"GO:0031301"(integral component of organelle membrane)|go:"GO:0042985"(negative regulation of amyloid precursor protein biosynthetic process)|interpro:IPR007084(BRICHOS)|interpro:IPR040145|mint:Q5XIE8|refseq:NP_001006964.1|rgd:620727	ensembl:ENSRNOG00000003206(gene)|ensembl:ENSRNOT00000004520(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001726"(ruffle)|go:"GO:0002102"(podosome)|go:"GO:0003779"(actin binding)|go:"GO:0005200"(structural constituent of cytoskeleton)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005885"(Arp2/3 protein complex)|go:"GO:0005903"(brush border)|go:"GO:0005911"(cell-cell junction)|go:"GO:0007163"(establishment or maintenance of cell polarity)|go:"GO:0007283"(spermatogenesis)|go:"GO:0008356"(asymmetric cell division)|go:"GO:0010592"(positive regulation of lamellipodium assembly)|go:"GO:0010763"(positive regulation of fibroblast migration)|go:"GO:0016344"(meiotic chromosome movement towards spindle pole)|go:"GO:0030027"(lamellipodium)|go:"GO:0030056"(hemidesmosome)|go:"GO:0030517"(negative regulation of axon extension)|go:"GO:0030838"(positive regulation of actin filament polymerization)|go:"GO:0031252"(cell leading edge)|go:"GO:0032092"(positive regulation of protein binding)|go:"GO:0032355"(response to estradiol)|go:"GO:0033206"(meiotic cytokinesis)|go:"GO:0034314"(Arp2/3 complex-mediated actin nucleation)|go:"GO:0035861"(site of double-strand break)|go:"GO:0035984"(cellular response to trichostatin A)|go:"GO:0043519"(regulation of myosin II filament organization)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0048708"(astrocyte differentiation)|go:"GO:0048711"(positive regulation of astrocyte differentiation)|go:"GO:0050775"(positive regulation of dendrite morphogenesis)|go:"GO:0051117"(ATPase binding)|go:"GO:0051321"(meiotic cell cycle)|go:"GO:0051491"(positive regulation of filopodium assembly)|go:"GO:0051653"(spindle localization)|go:"GO:0051965"(positive regulation of synapse assembly)|go:"GO:0060076"(excitatory synapse)|go:"GO:0060271"(cilium assembly)|go:"GO:0061003"(positive regulation of dendritic spine morphogenesis)|go:"GO:0061825"(podosome core)|go:"GO:0061828"(apical tubulobulbar complex)|go:"GO:0061830"(concave side of sperm head)|go:"GO:0061831"(apical ectoplasmic specialization)|go:"GO:0061832"(basal ectoplasmic specialization)|go:"GO:0061843"(Sertoli cell barrier remodeling)|go:"GO:0061851"(leading edge of lamellipodium)|go:"GO:0071346"(cellular response to interferon-gamma)|go:"GO:0071347"(cellular response to interleukin-1)|go:"GO:0071356"(cellular response to tumor necrosis factor)|go:"GO:0071364"(cellular response to epidermal growth factor stimulus)|go:"GO:0071503"(response to heparin)|go:"GO:0071560"(cellular response to transforming growth factor beta stimulus)|go:"GO:0090314"(positive regulation of protein targeting to membrane)|go:"GO:0098794"(postsynapse)|go:"GO:0098974"(postsynaptic actin cytoskeleton organization)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:1903078"(positive regulation of protein localization to plasma membrane)|go:"GO:1904171"(negative regulation of bleb assembly)|go:"GO:1905835"(cellular response to pyrimidine ribonucleotide)|go:"GO:1905837"(cellular response to triterpenoid)|go:"GO:2000251"(positive regulation of actin cytoskeleton reorganization)|interpro:IPR004000(Actin/actin-like)|interpro:IPR015623(Actin-related protein 3)|interpro:IPR020902|interpro:IPR043129|mint:Q4V7C7|reactome:R-RNO-2029482|reactome:R-RNO-3928662|reactome:R-RNO-5663213|reactome:R-RNO-8856828|go:"GO:0045666"(positive regulation of neuron differentiation)|refseq:NP_112330.1|rgd:71024	-	-	comment:mint	figure legend:ST1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10116(rat-brain-cerebellum)|taxid:10116(Rattus norvegicus)	-	2020/10/30	2020/10/30	rogid:DtE+ZXAZKdCMvUW5K+jXQ5bH07M10116	rogid:FBCctn7WChHon0MhVlJUO4ctinE10116	rigid:OaXQ9NA25fwCWxejPU3Ao9q5j/E	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q5XIE8	uniprotkb:P19945	intact:EBI-15348306|ensembl:ENSRNOP00000023037	intact:EBI-916785|ensembl:ENSRNOP00000001518	psi-mi:itm2b_rat(display_long)|uniprotkb:Itm2b(gene name)|psi-mi:Itm2b(display_short)|uniprotkb:Immature BRI2(gene name synonym)|uniprotkb:Transmembrane protein BRI(gene name synonym)	psi-mi:rla0_rat(display_long)|uniprotkb:60S ribosomal protein L10E(gene name synonym)|uniprotkb:Rplp0(gene name)|psi-mi:Rplp0(display_short)|uniprotkb:Arbp(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Martins et al. (2018)	imex:IM-28469|pubmed:29476059	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26438079|imex:IM-28469-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSRNOG00000016271(gene)|ensembl:ENSRNOT00000023037(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001540"(amyloid-beta binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0010008"(endosome membrane)|go:"GO:0030660"(Golgi-associated vesicle membrane)|go:"GO:0031301"(integral component of organelle membrane)|go:"GO:0042985"(negative regulation of amyloid precursor protein biosynthetic process)|interpro:IPR007084(BRICHOS)|interpro:IPR040145|mint:Q5XIE8|refseq:NP_001006964.1|rgd:620727	rgd:621247|refseq:NP_071797.1|ensembl:ENSRNOG00000001148(gene)|ensembl:ENSRNOT00000001518(transcript)|go:"GO:0000027"(ribosomal large subunit assembly)|go:"GO:0002181"(cytoplasmic translation)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0007595"(lactation)|go:"GO:0010269"(response to selenium ion)|go:"GO:0014069"(postsynaptic density)|go:"GO:0016020"(membrane)|go:"GO:0022625"(cytosolic large ribosomal subunit)|go:"GO:0022626"(cytosolic ribosome)|go:"GO:0030425"(dendrite)|go:"GO:0036464"(cytoplasmic ribonucleoprotein granule)|go:"GO:0042277"(peptide binding)|go:"GO:0045202"(synapse)|go:"GO:0070180"(large ribosomal subunit rRNA binding)|go:"GO:0071320"(cellular response to cAMP)|go:"GO:0071353"(cellular response to interleukin-4)|go:"GO:0098794"(postsynapse)|go:"GO:1904401"(cellular response to Thyroid stimulating hormone)|go:"GO:1904628"(cellular response to phorbol 13-acetate 12-myristate)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR001790(Ribosomal protein L10)|interpro:IPR030670|interpro:IPR040637|interpro:IPR043141|interpro:IPR043164|mint:P19945|reactome:R-RNO-156827|reactome:R-RNO-1799339|reactome:R-RNO-6791226|reactome:R-RNO-72689|reactome:R-RNO-72706|reactome:R-RNO-975956|reactome:R-RNO-975957	-	-	-	figure legend:ST1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10116(rat-brain-cerebellum)|taxid:10116(Rattus norvegicus)	-	2020/10/30	2020/10/30	rogid:DtE+ZXAZKdCMvUW5K+jXQ5bH07M10116	rogid:ZHQiXyp126dzMM4xe4iEDF2gd4810116	rigid:OaXQ9NA25fwCWxejPU3Ao9q5j/E	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q5XIE8	uniprotkb:Q01205	intact:EBI-15348306|ensembl:ENSRNOP00000023037	intact:EBI-918128|uniprotkb:Q5XI35	psi-mi:itm2b_rat(display_long)|uniprotkb:Itm2b(gene name)|psi-mi:Itm2b(display_short)|uniprotkb:Immature BRI2(gene name synonym)|uniprotkb:Transmembrane protein BRI(gene name synonym)	psi-mi:odo2_rat(display_long)|uniprotkb:Dihydrolipoamide succinyltransferase component of 2-oxoglutarate dehydrogenase complex(gene name synonym)|uniprotkb:E2K(gene name synonym)|uniprotkb:Dlst(gene name)|psi-mi:Dlst(display_short)|uniprotkb:2-oxoglutarate dehydrogenase complex component E2(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Martins et al. (2018)	imex:IM-28469|pubmed:29476059	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26438079|imex:IM-28469-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSRNOG00000016271(gene)|ensembl:ENSRNOT00000023037(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001540"(amyloid-beta binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0010008"(endosome membrane)|go:"GO:0030660"(Golgi-associated vesicle membrane)|go:"GO:0031301"(integral component of organelle membrane)|go:"GO:0042985"(negative regulation of amyloid precursor protein biosynthetic process)|interpro:IPR007084(BRICHOS)|interpro:IPR040145|mint:Q5XIE8|refseq:NP_001006964.1|rgd:620727	mint:Q01205|rgd:1359615|refseq:NP_001006982.2|interpro:IPR003016(2-oxo acid dehydrogenase, lipoyl-binding site)|interpro:IPR001078(Catalytic domain of components of various dehydrogenase complexes)|interpro:IPR000089(Biotin/lipoyl attachment)|interpro:IPR011053(Single hybrid motif)|interpro:IPR006255(Dihydrolipoamide succinyltransferase)|interpro:IPR023213|go:"GO:0004149"(dihydrolipoyllysine-residue succinyltransferase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005739"(mitochondrion)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0005886"(plasma membrane)|go:"GO:0006099"(tricarboxylic acid cycle)|go:"GO:0006103"(2-oxoglutarate metabolic process)|go:"GO:0006104"(succinyl-CoA metabolic process)|go:"GO:0006734"(NADH metabolic process)|go:"GO:0016746"(acyltransferase activity)|go:"GO:0031072"(heat shock protein binding)|go:"GO:0033512"(L-lysine catabolic process to acetyl-CoA via saccharopine)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0045252"(oxoglutarate dehydrogenase complex)|go:"GO:0051087"(chaperone binding)|go:"GO:0106077"(histone succinylation)|reactome:R-RNO-389661|reactome:R-RNO-71064|reactome:R-RNO-71403	-	-	-	figure legend:ST1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10116(rat-brain-cerebellum)|taxid:10116(Rattus norvegicus)	-	2020/10/30	2020/10/30	rogid:DtE+ZXAZKdCMvUW5K+jXQ5bH07M10116	rogid:Ytjw7Tvj7aVaGmQksyMIBlweGUk10116	rigid:OaXQ9NA25fwCWxejPU3Ao9q5j/E	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q5XIE8	uniprotkb:P20788	intact:EBI-15348306|ensembl:ENSRNOP00000023037	intact:EBI-931318|uniprotkb:Q6QI13|ensembl:ENSRNOP00000024609	psi-mi:itm2b_rat(display_long)|uniprotkb:Itm2b(gene name)|psi-mi:Itm2b(display_short)|uniprotkb:Immature BRI2(gene name synonym)|uniprotkb:Transmembrane protein BRI(gene name synonym)	psi-mi:ucri_rat(display_long)|uniprotkb:Rieske protein UQCRFS1(gene name synonym)|uniprotkb:Uqcrfs1(gene name)|psi-mi:Uqcrfs1(display_short)|uniprotkb:Ubiquinol-cytochrome c reductase iron-sulfur subunit(gene name synonym)|uniprotkb:Rieske iron-sulfur protein(gene name synonym)|uniprotkb:Complex III subunit 5(gene name synonym)|uniprotkb:Liver regeneration-related protein LRRGT00195(gene name synonym)|uniprotkb:Cytochrome b-c1 complex subunit 5(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Martins et al. (2018)	imex:IM-28469|pubmed:29476059	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26438079|imex:IM-28469-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSRNOG00000016271(gene)|ensembl:ENSRNOT00000023037(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001540"(amyloid-beta binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0010008"(endosome membrane)|go:"GO:0030660"(Golgi-associated vesicle membrane)|go:"GO:0031301"(integral component of organelle membrane)|go:"GO:0042985"(negative regulation of amyloid precursor protein biosynthetic process)|interpro:IPR007084(BRICHOS)|interpro:IPR040145|mint:Q5XIE8|refseq:NP_001006964.1|rgd:620727	rgd:628838|refseq:NP_001008888.1|ensembl:ENSRNOG00000018281(gene)|ensembl:ENSRNOT00000024609(transcript)|go:"GO:0005739"(mitochondrion)|go:"GO:0005750"(mitochondrial respiratory chain complex III)|go:"GO:0005751"(mitochondrial respiratory chain complex IV)|go:"GO:0008121"(ubiquinol-cytochrome-c reductase activity)|go:"GO:0009725"(response to hormone)|go:"GO:0016491"(oxidoreductase activity)|go:"GO:0022904"(respiratory electron transport chain)|go:"GO:0031966"(mitochondrial membrane)|go:"GO:0034551"(mitochondrial respiratory chain complex III assembly)|go:"GO:0042493"|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045275"(respiratory chain complex III)|go:"GO:0046677"(response to antibiotic)|go:"GO:0046872"(metal ion binding)|go:"GO:0051537"(2 iron, 2 sulfur cluster binding)|interpro:IPR004192(Ubiquinol cytochrome reductase transmembrane region)|interpro:IPR005805(Rieske iron-sulphur protein, C-terminal)|interpro:IPR006317(Ubiquinol-cytochrome c reductase, iron-sulphur subunit)|interpro:IPR011070(Globular protein, non-globular alpha/beta subunit)|interpro:IPR014349(Rieske iron-sulphur protein)|interpro:IPR015248(Ubiquinol-cytochrome c reductase 8 kDa, N-terminal)|interpro:IPR017941|interpro:IPR036922|interpro:IPR037008|mint:P20788|reactome:R-RNO-611105	-	-	-	figure legend:ST1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10116(rat-brain-cerebellum)|taxid:10116(Rattus norvegicus)	-	2020/10/30	2020/10/30	rogid:DtE+ZXAZKdCMvUW5K+jXQ5bH07M10116	rogid:MLzi+0uooHySBqxsDJ7MItr9r8E10116	rigid:OaXQ9NA25fwCWxejPU3Ao9q5j/E	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q5XIE8	uniprotkb:P13233	intact:EBI-15348306|ensembl:ENSRNOP00000023037	intact:EBI-2640672|uniprotkb:Q4V796|uniprotkb:Q64575|ensembl:ENSRNOP00000023875	psi-mi:itm2b_rat(display_long)|uniprotkb:Itm2b(gene name)|psi-mi:Itm2b(display_short)|uniprotkb:Immature BRI2(gene name synonym)|uniprotkb:Transmembrane protein BRI(gene name synonym)	psi-mi:cn37_rat(display_long)|uniprotkb:Cnp(gene name)|psi-mi:Cnp(display_short)|uniprotkb:Cnp1(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Martins et al. (2018)	imex:IM-28469|pubmed:29476059	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26438079|imex:IM-28469-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSRNOG00000016271(gene)|ensembl:ENSRNOT00000023037(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001540"(amyloid-beta binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0010008"(endosome membrane)|go:"GO:0030660"(Golgi-associated vesicle membrane)|go:"GO:0031301"(integral component of organelle membrane)|go:"GO:0042985"(negative regulation of amyloid precursor protein biosynthetic process)|interpro:IPR007084(BRICHOS)|interpro:IPR040145|mint:Q5XIE8|refseq:NP_001006964.1|rgd:620727	rgd:2368|refseq:NP_036941.1|ensembl:ENSRNOG00000017496(gene)|ensembl:ENSRNOT00000023872(transcript)|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0003723"(RNA binding)|go:"GO:0004113"(2',3'-cyclic-nucleotide 3'-phosphodiesterase activity)|go:"GO:0005615"(extracellular space)|go:"GO:0005737"(cytoplasm)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005886"(plasma membrane)|go:"GO:0005902"(microvillus)|go:"GO:0007409"(axonogenesis)|go:"GO:0007568"(aging)|go:"GO:0008344"(adult locomotory behavior)|go:"GO:0009214"(cyclic nucleotide catabolic process)|go:"GO:0009636"(response to toxic substance)|go:"GO:0016020"(membrane)|go:"GO:0030551"(cyclic nucleotide binding)|go:"GO:0030900"(forebrain development)|go:"GO:0031143"(pseudopodium)|go:"GO:0032496"(response to lipopolysaccharide)|go:"GO:0035748"(myelin sheath abaxonal region)|go:"GO:0035749"(myelin sheath adaxonal region)|go:"GO:0042470"(melanosome)|go:"GO:0042995"(cell projection)|go:"GO:0043209"(myelin sheath)|go:"GO:0046902"(regulation of mitochondrial membrane permeability)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0048709"(oligodendrocyte differentiation)|interpro:IPR008431(Cyclic nucleotide phosphodiesterase)|interpro:IPR009097(RNA ligase/cyclic nucleotide phosphodiesterase)|interpro:IPR027417|mint:P13233|rcsb pdb:2ILX	-	-	-	figure legend:ST1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10116(rat-brain-cerebellum)|taxid:10116(Rattus norvegicus)	-	2020/10/30	2020/10/30	rogid:DtE+ZXAZKdCMvUW5K+jXQ5bH07M10116	rogid:+0AAow8yyo0d6aKTghtTmcS2SZw10116	rigid:OaXQ9NA25fwCWxejPU3Ao9q5j/E	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q5XIE8	uniprotkb:P01830	intact:EBI-15348306|ensembl:ENSRNOP00000023037	intact:EBI-2255860|ensembl:ENSRNOP00000008685	psi-mi:itm2b_rat(display_long)|uniprotkb:Itm2b(gene name)|psi-mi:Itm2b(display_short)|uniprotkb:Immature BRI2(gene name synonym)|uniprotkb:Transmembrane protein BRI(gene name synonym)	psi-mi:thy1_rat(display_long)|uniprotkb:Thy1(gene name)|psi-mi:Thy1(display_short)|uniprotkb:Thy-1(gene name synonym)|uniprotkb:Thy-1 antigen(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Martins et al. (2018)	imex:IM-28469|pubmed:29476059	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26438079|imex:IM-28469-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSRNOG00000016271(gene)|ensembl:ENSRNOT00000023037(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001540"(amyloid-beta binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0010008"(endosome membrane)|go:"GO:0030660"(Golgi-associated vesicle membrane)|go:"GO:0031301"(integral component of organelle membrane)|go:"GO:0042985"(negative regulation of amyloid precursor protein biosynthetic process)|interpro:IPR007084(BRICHOS)|interpro:IPR040145|mint:Q5XIE8|refseq:NP_001006964.1|rgd:620727	rgd:3860|refseq:NP_036805.1|dip:DIP-1031N|ensembl:ENSRNOG00000006604(gene)|ensembl:ENSRNOT00000008685(transcript)|go:"GO:0001525"(angiogenesis)|go:"GO:0001952"(regulation of cell-matrix adhesion)|go:"GO:0002693"(positive regulation of cellular extravasation)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005178"(integrin binding)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006469"(negative regulation of protein kinase activity)|go:"GO:0007010"(cytoskeleton organization)|go:"GO:0007229"(integrin-mediated signaling pathway)|go:"GO:0007267"(cell-cell signaling)|go:"GO:0009897"(external side of plasma membrane)|go:"GO:0009986"(cell surface)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0019899"(enzyme binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030336"(negative regulation of cell migration)|go:"GO:0030425"(dendrite)|go:"GO:0030426"(growth cone)|go:"GO:0030673"(axolemma)|go:"GO:0031362"(anchored component of external side of plasma membrane)|go:"GO:0032590"(dendrite membrane)|go:"GO:0032809"(neuronal cell body membrane)|go:"GO:0034116"(positive regulation of heterotypic cell-cell adhesion)|go:"GO:0034235"(GPI anchor binding)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043113"(receptor clustering)|go:"GO:0043547"(positive regulation of GTPase activity)|go:"GO:0045121"(membrane raft)|go:"GO:0045576"(mast cell activation)|go:"GO:0046549"(retinal cone cell development)|go:"GO:0046658"(anchored component of plasma membrane)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0048041"(focal adhesion assembly)|go:"GO:0048147"(negative regulation of fibroblast proliferation)|go:"GO:0050731"(positive regulation of peptidyl-tyrosine phosphorylation)|go:"GO:0050771"(negative regulation of axonogenesis)|go:"GO:0050852"(T cell receptor signaling pathway)|go:"GO:0050860"(negative regulation of T cell receptor signaling pathway)|go:"GO:0050870"(positive regulation of T cell activation)|go:"GO:0051281"(positive regulation of release of sequestered calcium ion into cytosol)|go:"GO:0051894"(positive regulation of focal adhesion assembly)|go:"GO:0061099"(negative regulation of protein tyrosine kinase activity)|go:"GO:0070571"(negative regulation of neuron projection regeneration)|go:"GO:0098609"(cell-cell adhesion)|go:"GO:2000298"(regulation of Rho-dependent protein serine/threonine kinase activity)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR013106(Immunoglobulin V-set)|interpro:IPR013151(Immunoglobulin)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR033292|interpro:IPR036179|mint:P01830|reactome:R-RNO-163125	-	-	-	figure legend:ST1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10116(rat-brain-cerebellum)|taxid:10116(Rattus norvegicus)	-	2020/10/30	2020/10/30	rogid:DtE+ZXAZKdCMvUW5K+jXQ5bH07M10116	rogid:P4seZqeNePRK65KZGl6CVdenFHk10116	rigid:OaXQ9NA25fwCWxejPU3Ao9q5j/E	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q5XIE8	uniprotkb:Q6P502	intact:EBI-15348306|ensembl:ENSRNOP00000023037	intact:EBI-918953|ensembl:ENSRNOP00000025824	psi-mi:itm2b_rat(display_long)|uniprotkb:Itm2b(gene name)|psi-mi:Itm2b(display_short)|uniprotkb:Immature BRI2(gene name synonym)|uniprotkb:Transmembrane protein BRI(gene name synonym)	psi-mi:tcpg_rat(display_long)|uniprotkb:Cct3(gene name)|psi-mi:Cct3(display_short)|uniprotkb:CCT-gamma(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Martins et al. (2018)	imex:IM-28469|pubmed:29476059	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26438079|imex:IM-28469-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSRNOG00000016271(gene)|ensembl:ENSRNOT00000023037(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001540"(amyloid-beta binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0010008"(endosome membrane)|go:"GO:0030660"(Golgi-associated vesicle membrane)|go:"GO:0031301"(integral component of organelle membrane)|go:"GO:0042985"(negative regulation of amyloid precursor protein biosynthetic process)|interpro:IPR007084(BRICHOS)|interpro:IPR040145|mint:Q5XIE8|refseq:NP_001006964.1|rgd:620727	rgd:735038|refseq:NP_954522.1|ensembl:ENSRNOG00000019090(gene)|ensembl:ENSRNOT00000025824(transcript)|go:"GO:0002199"(zona pellucida receptor complex)|go:"GO:0005524"(ATP binding)|go:"GO:0005832"(chaperonin-containing T-complex)|go:"GO:0005874"(microtubule)|go:"GO:0006457"(protein folding)|go:"GO:0007339"(binding of sperm to zona pellucida)|go:"GO:0032212"(positive regulation of telomere maintenance via telomerase)|go:"GO:0044183"(protein folding chaperone)|go:"GO:0044297"(cell body)|go:"GO:0046931"(pore complex assembly)|go:"GO:0050821"(protein stabilization)|go:"GO:0051082"(unfolded protein binding)|go:"GO:1901998"(toxin transport)|go:"GO:1904851"(positive regulation of establishment of protein localization to telomere)|interpro:IPR002194(Chaperonin TCP-1, conserved site)|interpro:IPR002423(Chaperonin Cpn60/TCP-1)|interpro:IPR012719(T-complex protein 1, gamma subunit)|interpro:IPR017998|interpro:IPR027409|interpro:IPR027410|interpro:IPR027413|mint:Q6P502|reactome:R-RNO-390471|reactome:R-RNO-5620922|reactome:R-RNO-6814122	-	-	-	figure legend:ST1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10116(rat-brain-cerebellum)|taxid:10116(Rattus norvegicus)	-	2020/10/30	2020/10/30	rogid:DtE+ZXAZKdCMvUW5K+jXQ5bH07M10116	rogid:1JIKeXK/jQ/vqkYLjBGcrCj1PDg10116	rigid:OaXQ9NA25fwCWxejPU3Ao9q5j/E	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q5XIE8	uniprotkb:Q7TPB1	intact:EBI-15348306|ensembl:ENSRNOP00000023037	intact:EBI-919426|ensembl:ENSRNOP00000012847	psi-mi:itm2b_rat(display_long)|uniprotkb:Itm2b(gene name)|psi-mi:Itm2b(display_short)|uniprotkb:Immature BRI2(gene name synonym)|uniprotkb:Transmembrane protein BRI(gene name synonym)	psi-mi:tcpd_rat(display_long)|uniprotkb:Cct4(gene name)|psi-mi:Cct4(display_short)|uniprotkb:CCT-delta(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Martins et al. (2018)	imex:IM-28469|pubmed:29476059	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26438079|imex:IM-28469-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSRNOG00000016271(gene)|ensembl:ENSRNOT00000023037(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001540"(amyloid-beta binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0010008"(endosome membrane)|go:"GO:0030660"(Golgi-associated vesicle membrane)|go:"GO:0031301"(integral component of organelle membrane)|go:"GO:0042985"(negative regulation of amyloid precursor protein biosynthetic process)|interpro:IPR007084(BRICHOS)|interpro:IPR040145|mint:Q5XIE8|refseq:NP_001006964.1|rgd:620727	rgd:727937|refseq:NP_877966.1|ensembl:ENSRNOG00000009642(gene)|ensembl:ENSRNOT00000012847(transcript)|go:"GO:0002199"(zona pellucida receptor complex)|go:"GO:0005524"(ATP binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005832"(chaperonin-containing T-complex)|go:"GO:0005874"(microtubule)|go:"GO:0005929"(cilium)|go:"GO:0006457"(protein folding)|go:"GO:0007339"(binding of sperm to zona pellucida)|go:"GO:0032212"(positive regulation of telomere maintenance via telomerase)|go:"GO:0042470"(melanosome)|go:"GO:0044183"(protein folding chaperone)|go:"GO:0044297"(cell body)|go:"GO:0050821"(protein stabilization)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0051973"(positive regulation of telomerase activity)|go:"GO:0090666"(scaRNA localization to Cajal body)|go:"GO:1901998"(toxin transport)|go:"GO:1904851"(positive regulation of establishment of protein localization to telomere)|go:"GO:1904874"(positive regulation of telomerase RNA localization to Cajal body)|interpro:IPR002194(Chaperonin TCP-1, conserved site)|interpro:IPR002423(Chaperonin Cpn60/TCP-1)|interpro:IPR012717(T-complex protein 1, delta subunit)|interpro:IPR017998|interpro:IPR027409|interpro:IPR027410|interpro:IPR027413|mint:Q7TPB1|reactome:R-RNO-390471|reactome:R-RNO-5620922|reactome:R-RNO-6814122	-	-	-	figure legend:ST1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10116(rat-brain-cerebellum)|taxid:10116(Rattus norvegicus)	-	2020/10/30	2020/10/30	rogid:DtE+ZXAZKdCMvUW5K+jXQ5bH07M10116	rogid:xYiR/DP4M2RW1MeQwg2Sb9M77xc10116	rigid:OaXQ9NA25fwCWxejPU3Ao9q5j/E	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q5XIE8	uniprotkb:Q5XIM9	intact:EBI-15348306|ensembl:ENSRNOP00000023037	intact:EBI-920517|ensembl:ENSRNOP00000029234	psi-mi:itm2b_rat(display_long)|uniprotkb:Itm2b(gene name)|psi-mi:Itm2b(display_short)|uniprotkb:Immature BRI2(gene name synonym)|uniprotkb:Transmembrane protein BRI(gene name synonym)	psi-mi:tcpb_rat(display_long)|uniprotkb:Cct2(gene name)|psi-mi:Cct2(display_short)|uniprotkb:CCT-beta(gene name synonym)|uniprotkb:Cctb(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Martins et al. (2018)	imex:IM-28469|pubmed:29476059	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26438079|imex:IM-28469-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSRNOG00000016271(gene)|ensembl:ENSRNOT00000023037(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001540"(amyloid-beta binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0010008"(endosome membrane)|go:"GO:0030660"(Golgi-associated vesicle membrane)|go:"GO:0031301"(integral component of organelle membrane)|go:"GO:0042985"(negative regulation of amyloid precursor protein biosynthetic process)|interpro:IPR007084(BRICHOS)|interpro:IPR040145|mint:Q5XIE8|refseq:NP_001006964.1|rgd:620727	rgd:1359143|refseq:NP_001005905.1|ensembl:ENSRNOG00000021317(gene)|ensembl:ENSRNOT00000037946(transcript)|go:"GO:0002199"(zona pellucida receptor complex)|go:"GO:0005524"(ATP binding)|go:"GO:0005832"(chaperonin-containing T-complex)|go:"GO:0005874"(microtubule)|go:"GO:0006457"(protein folding)|go:"GO:0007339"(binding of sperm to zona pellucida)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032212"(positive regulation of telomere maintenance via telomerase)|go:"GO:0044183"(protein folding chaperone)|go:"GO:0044297"(cell body)|go:"GO:0050821"(protein stabilization)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0051086"(chaperone mediated protein folding independent of cofactor)|go:"GO:0051131"(chaperone-mediated protein complex assembly)|go:"GO:0051973"(positive regulation of telomerase activity)|go:"GO:0090666"(scaRNA localization to Cajal body)|go:"GO:1901998"(toxin transport)|go:"GO:1904851"(positive regulation of establishment of protein localization to telomere)|go:"GO:1904874"(positive regulation of telomerase RNA localization to Cajal body)|interpro:IPR002194(Chaperonin TCP-1, conserved site)|interpro:IPR002423(Chaperonin Cpn60/TCP-1)|interpro:IPR012716(T-complex protein 1, beta subunit)|interpro:IPR017998|interpro:IPR027409|interpro:IPR027410|interpro:IPR027413|mint:Q5XIM9|reactome:R-RNO-390471|reactome:R-RNO-5620922|reactome:R-RNO-6798695|reactome:R-RNO-6814122|reactome:R-RNO-9013418|reactome:R-RNO-9013422	-	-	-	figure legend:ST1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10116(rat-brain-cerebellum)|taxid:10116(Rattus norvegicus)	-	2020/10/30	2020/10/30	rogid:DtE+ZXAZKdCMvUW5K+jXQ5bH07M10116	rogid:JKr4ca8SpJ/EnpoJsDazwn8L6hc10116	rigid:OaXQ9NA25fwCWxejPU3Ao9q5j/E	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q5XIE8	uniprotkb:P60881	intact:EBI-15348306|ensembl:ENSRNOP00000023037	intact:EBI-1027214|uniprotkb:P13795|uniprotkb:P36974|uniprotkb:P70557|uniprotkb:P70558|uniprotkb:Q8IXK3|uniprotkb:Q96FM2|uniprotkb:Q9BR45|intact:EBI-11701410	psi-mi:itm2b_rat(display_long)|uniprotkb:Itm2b(gene name)|psi-mi:Itm2b(display_short)|uniprotkb:Immature BRI2(gene name synonym)|uniprotkb:Transmembrane protein BRI(gene name synonym)	psi-mi:snp25_rat(display_long)|uniprotkb:Snap25(gene name)|psi-mi:Snap25(display_short)|uniprotkb:Snap(gene name synonym)|uniprotkb:Synaptosomal-associated 25 kDa protein(gene name synonym)|uniprotkb:Super protein(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Martins et al. (2018)	imex:IM-28469|pubmed:29476059	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26438079|imex:IM-28469-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSRNOG00000016271(gene)|ensembl:ENSRNOT00000023037(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001540"(amyloid-beta binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0010008"(endosome membrane)|go:"GO:0030660"(Golgi-associated vesicle membrane)|go:"GO:0031301"(integral component of organelle membrane)|go:"GO:0042985"(negative regulation of amyloid precursor protein biosynthetic process)|interpro:IPR007084(BRICHOS)|interpro:IPR040145|mint:Q5XIE8|refseq:NP_001006964.1|rgd:620727	go:"GO:0000149"(SNARE binding)|go:"GO:0001917"(photoreceptor inner segment)|go:"GO:0005249"(voltage-gated potassium channel activity)|go:"GO:0005484"(SNAP receptor activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005886"(plasma membrane)|go:"GO:0006887"(exocytosis)|go:"GO:0006906"(vesicle fusion)|go:"GO:0007269"(neurotransmitter secretion)|go:"GO:0007409"(axonogenesis)|go:"GO:0007616"(long-term memory)|go:"GO:0007626"(locomotory behavior)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0008076"(voltage-gated potassium channel complex)|go:"GO:0008306"(associative learning)|go:"GO:0010975"(regulation of neuron projection development)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0016020"(membrane)|go:"GO:0016079"(synaptic vesicle exocytosis)|go:"GO:0016082"(synaptic vesicle priming)|go:"GO:0016197"(endosomal transport)|go:"GO:0017022"(myosin binding)|go:"GO:0017075"(syntaxin-1 binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0019905"(syntaxin binding)|go:"GO:0030027"(lamellipodium)|go:"GO:0030175"(filopodium)|go:"GO:0030182"(neuron differentiation)|go:"GO:0030252"(growth hormone secretion)|go:"GO:0030424"(axon)|go:"GO:0030426"(growth cone)|go:"GO:0030431"(sleep)|go:"GO:0031201"(SNARE complex)|go:"GO:0031234"(extrinsic component of cytoplasmic side of plasma membrane)|go:"GO:0031629"(synaptic vesicle fusion to presynaptic active zone membrane)|go:"GO:0032024"(positive regulation of insulin secretion)|go:"GO:0035493"(SNARE complex assembly)|go:"GO:0036477"(somatodendritic compartment)|go:"GO:0042734"(presynaptic membrane)|go:"GO:0043005"(neuron projection)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043195"(terminal bouton)|go:"GO:0043229"(intracellular organelle)|go:"GO:0044295"(axonal growth cone)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0045121"(membrane raft)|go:"GO:0045202"(synapse)|go:"GO:0046887"(positive regulation of hormone secretion)|go:"GO:0047485"(protein N-terminus binding)|go:"GO:0048306"(calcium-dependent protein binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0048787"(presynaptic active zone membrane)|go:"GO:0048791"(calcium ion-regulated exocytosis of neurotransmitter)|go:"GO:0051963"(regulation of synapse assembly)|go:"GO:0070032"(synaptobrevin 2-SNAP-25-syntaxin-1a-complexin I complex)|go:"GO:0070033"(synaptobrevin 2-SNAP-25-syntaxin-1a-complexin II complex)|go:"GO:0070044"(synaptobrevin 2-SNAP-25-syntaxin-1a complex)|go:"GO:0070201"(regulation of establishment of protein localization)|go:"GO:0098794"(postsynapse)|go:"GO:0098967"(exocytic insertion of neurotransmitter receptor to postsynaptic membrane)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099026"(anchored component of presynaptic membrane)|go:"GO:0099590"(neurotransmitter receptor internalization)|interpro:IPR000727(Target SNARE coiled-coil region)|interpro:IPR000928(SNAP-25)|interpro:IPR039077|rcsb pdb:1JTH|rcsb pdb:1N7S|rcsb pdb:1SFC|rcsb pdb:1URQ|rcsb pdb:3HD7|rcsb pdb:3IPD|rcsb pdb:3J96|rcsb pdb:3J97|rcsb pdb:3J98|rcsb pdb:3J99|rcsb pdb:5CCG|rcsb pdb:5CCH|rcsb pdb:5CCI|rcsb pdb:5KJ7|rcsb pdb:5KJ8|rcsb pdb:5LOB|rcsb pdb:5LOW|rcsb pdb:5W5C|rcsb pdb:5W5D|rcsb pdb:6IP1|rcsb pdb:6MDM|rcsb pdb:6MDN|rcsb pdb:6MDO|rcsb pdb:6MDP|go:"GO:0060291"(long-term synaptic potentiation)|rcsb pdb:6MTI|rcsb pdb:6WVW|reactome:R-RNO-181429|reactome:R-RNO-181430|reactome:R-RNO-210500|reactome:R-RNO-212676|reactome:R-RNO-264642|reactome:R-RNO-449836|reactome:R-RNO-6798695|reactome:R-RNO-888590|rgd:3728|refseq:NP_112253.1|refseq:NP_001257504.1|refseq:NP_001257505.1|mint:P60881|dip:DIP-29205N	-	-	-	figure legend:ST1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10116(rat-brain-cerebellum)|taxid:10116(Rattus norvegicus)	-	2020/10/30	2020/10/30	rogid:DtE+ZXAZKdCMvUW5K+jXQ5bH07M10116	rogid:/Z7IJEKvHKJbZS4f4oDDyluztHs10116	rigid:OaXQ9NA25fwCWxejPU3Ao9q5j/E	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q5XIE8	uniprotkb:P50399	intact:EBI-15348306|ensembl:ENSRNOP00000023037	intact:EBI-8848546|uniprotkb:Q6P797|ensembl:ENSRNOP00000024952	psi-mi:itm2b_rat(display_long)|uniprotkb:Itm2b(gene name)|psi-mi:Itm2b(display_short)|uniprotkb:Immature BRI2(gene name synonym)|uniprotkb:Transmembrane protein BRI(gene name synonym)	psi-mi:gdib_rat(display_long)|uniprotkb:Gdi2(gene name)|psi-mi:Gdi2(display_short)|uniprotkb:Gdi3(gene name synonym)|uniprotkb:GDI-3(gene name synonym)|uniprotkb:Guanosine diphosphate dissociation inhibitor 2(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Martins et al. (2018)	imex:IM-28469|pubmed:29476059	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26438079|imex:IM-28469-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSRNOG00000016271(gene)|ensembl:ENSRNOT00000023037(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001540"(amyloid-beta binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0010008"(endosome membrane)|go:"GO:0030660"(Golgi-associated vesicle membrane)|go:"GO:0031301"(integral component of organelle membrane)|go:"GO:0042985"(negative regulation of amyloid precursor protein biosynthetic process)|interpro:IPR007084(BRICHOS)|interpro:IPR040145|mint:Q5XIE8|refseq:NP_001006964.1|rgd:620727	refseq:NP_058972.2|rgd:61802|ensembl:ENSRNOG00000018091(gene)|ensembl:ENSRNOT00000024952(transcript)|go:"GO:0005093"(Rab GDP-dissociation inhibitor activity)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0007264"(small GTPase mediated signal transduction)|go:"GO:0015031"(protein transport)|go:"GO:0016020"(membrane)|go:"GO:0016192"(vesicle-mediated transport)|go:"GO:0031267"(small GTPase binding)|go:"GO:0045202"(synapse)|interpro:IPR000806(Rab GDI protein)|interpro:IPR018203|interpro:IPR036188|mint:P50399|reactome:R-RNO-6798695|reactome:R-RNO-8876198	-	-	-	figure legend:ST1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10116(rat-brain-cerebellum)|taxid:10116(Rattus norvegicus)	-	2020/10/30	2020/10/30	rogid:DtE+ZXAZKdCMvUW5K+jXQ5bH07M10116	rogid:+ngZz9q02lDEdFO543w/yl6chgc10116	rigid:OaXQ9NA25fwCWxejPU3Ao9q5j/E	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q5XIE8	uniprotkb:P16409	intact:EBI-15348306|ensembl:ENSRNOP00000023037	intact:EBI-26438054|ensembl:ENSRNOP00000028458	psi-mi:itm2b_rat(display_long)|uniprotkb:Itm2b(gene name)|psi-mi:Itm2b(display_short)|uniprotkb:Immature BRI2(gene name synonym)|uniprotkb:Transmembrane protein BRI(gene name synonym)	psi-mi:myl3_rat(display_long)|uniprotkb:Myl3(gene name)|psi-mi:Myl3(display_short)|uniprotkb:Mlc1v(gene name synonym)|uniprotkb:Myosin alkali light chain 1, ventricular(gene name synonym)|uniprotkb:Myosin light chain 1, slow-twitch muscle B/ventricular isoform(gene name synonym)|uniprotkb:Ventricular myosin light chain 1(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Martins et al. (2018)	imex:IM-28469|pubmed:29476059	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26438079|imex:IM-28469-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSRNOG00000016271(gene)|ensembl:ENSRNOT00000023037(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001540"(amyloid-beta binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0010008"(endosome membrane)|go:"GO:0030660"(Golgi-associated vesicle membrane)|go:"GO:0031301"(integral component of organelle membrane)|go:"GO:0042985"(negative regulation of amyloid precursor protein biosynthetic process)|interpro:IPR007084(BRICHOS)|interpro:IPR040145|mint:Q5XIE8|refseq:NP_001006964.1|rgd:620727	ensembl:ENSRNOT00000028458(transcript)|go:"GO:0002026"(regulation of the force of heart contraction)|go:"GO:0003774"(cytoskeletal motor activity)|go:"GO:0003785"(actin monomer binding)|go:"GO:0005509"(calcium ion binding)|go:"GO:0006936"(muscle contraction)|go:"GO:0006942"(regulation of striated muscle contraction)|go:"GO:0007519"(skeletal muscle tissue development)|go:"GO:0016459"(myosin complex)|go:"GO:0031672"(A band)|go:"GO:0031674"(I band)|go:"GO:0055010"(ventricular cardiac muscle tissue morphogenesis)|go:"GO:0060048"(cardiac muscle contraction)|interpro:IPR002048(Calcium-binding EF-hand)|interpro:IPR011992(EF-Hand type)|mint:P16409|reactome:R-RNO-390522|ensembl:ENSRNOG00000020955(gene)|refseq:NP_036738.1|refseq:XP_006243979.3|rgd:3142	-	-	-	figure legend:ST1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10116(rat-brain-cerebellum)|taxid:10116(Rattus norvegicus)	-	2020/10/30	2020/10/30	rogid:DtE+ZXAZKdCMvUW5K+jXQ5bH07M10116	rogid:zxLulGJOfj/nNh15aQrPvpoFsWc10116	rigid:OaXQ9NA25fwCWxejPU3Ao9q5j/E	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q5XIE8	uniprotkb:Q5RKI1	intact:EBI-15348306|ensembl:ENSRNOP00000023037	intact:EBI-22250960|ensembl:ENSRNOP00000002484	psi-mi:itm2b_rat(display_long)|uniprotkb:Itm2b(gene name)|psi-mi:Itm2b(display_short)|uniprotkb:Immature BRI2(gene name synonym)|uniprotkb:Transmembrane protein BRI(gene name synonym)	psi-mi:if4a2_rat(display_long)|uniprotkb:ATP-dependent RNA helicase eIF4A-2(gene name synonym)|uniprotkb:Eif4a2(gene name)|psi-mi:Eif4a2(display_short)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Martins et al. (2018)	imex:IM-28469|pubmed:29476059	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26438079|imex:IM-28469-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSRNOG00000016271(gene)|ensembl:ENSRNOT00000023037(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001540"(amyloid-beta binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0010008"(endosome membrane)|go:"GO:0030660"(Golgi-associated vesicle membrane)|go:"GO:0031301"(integral component of organelle membrane)|go:"GO:0042985"(negative regulation of amyloid precursor protein biosynthetic process)|interpro:IPR007084(BRICHOS)|interpro:IPR040145|mint:Q5XIE8|refseq:NP_001006964.1|rgd:620727	ensembl:ENSRNOG00000001815(gene)|ensembl:ENSRNOT00000002484(transcript)|go:"GO:0002183"(cytoplasmic translational initiation)|go:"GO:0003743"(translation initiation factor activity)|go:"GO:0005524"(ATP binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|go:"GO:1900260"(negative regulation of RNA-directed 5'-3' RNA polymerase activity)|go:"GO:1990830"(cellular response to leukemia inhibitory factor)|interpro:IPR000629(RNA helicase, ATP-dependent, DEAD-box, conserved site)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR011545(DNA/RNA helicase, DEAD/DEAH box type, N-terminal)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR014014(RNA helicase, DEAD-box type, Q motif)|interpro:IPR027417|interpro:IPR044728|mint:Q5RKI1|reactome:R-RNO-1169408|reactome:R-RNO-156827|reactome:R-RNO-429947|reactome:R-RNO-72649|reactome:R-RNO-72662|reactome:R-RNO-72702|reactome:R-RNO-72706|go:"GO:0003724"(RNA helicase activity)|refseq:NP_001008336.1|rgd:1309225	-	-	-	figure legend:ST1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10116(rat-brain-cerebellum)|taxid:10116(Rattus norvegicus)	-	2020/10/30	2020/10/30	rogid:DtE+ZXAZKdCMvUW5K+jXQ5bH07M10116	rogid:m9i/jWfsbU+6kQvj1h06x31+awg10116	rigid:OaXQ9NA25fwCWxejPU3Ao9q5j/E	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q5XIE8	uniprotkb:P62161	intact:EBI-15348306|ensembl:ENSRNOP00000023037	intact:EBI-397530|uniprotkb:P02593|uniprotkb:P70667|uniprotkb:P99014|uniprotkb:Q61379|uniprotkb:Q61380|dip:DIP-29528N|refseq:NP_059022|uniprotkb:P0DP30	psi-mi:itm2b_rat(display_long)|uniprotkb:Itm2b(gene name)|psi-mi:Itm2b(display_short)|uniprotkb:Immature BRI2(gene name synonym)|uniprotkb:Transmembrane protein BRI(gene name synonym)	psi-mi:calm_rat(display_long)|uniprotkb:Calm1(gene name)|psi-mi:Calm1(display_short)|uniprotkb:Calm(gene name synonym)|uniprotkb:Cam(gene name synonym)|uniprotkb:Cam1(gene name synonym)|uniprotkb:Calm2(gene name)|psi-mi:Calm2(display_short)|uniprotkb:Cam2(gene name synonym)|uniprotkb:Camb(gene name synonym)|uniprotkb:Calm3(gene name)|psi-mi:Calm3(display_short)|uniprotkb:Cam3(gene name synonym)|uniprotkb:Camc(gene name synonym)|uniprotkb:CaMII(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Martins et al. (2018)	imex:IM-28469|pubmed:29476059	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26438079|imex:IM-28469-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSRNOG00000016271(gene)|ensembl:ENSRNOT00000023037(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001540"(amyloid-beta binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0010008"(endosome membrane)|go:"GO:0030660"(Golgi-associated vesicle membrane)|go:"GO:0031301"(integral component of organelle membrane)|go:"GO:0042985"(negative regulation of amyloid precursor protein biosynthetic process)|interpro:IPR007084(BRICHOS)|interpro:IPR040145|mint:Q5XIE8|refseq:NP_001006964.1|rgd:620727	rcsb pdb:4G27|rcsb pdb:4G28|go:"GO:0030426"(growth cone)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0047485"(protein N-terminus binding)|go:"GO:0050998"(nitric-oxide synthase binding)|go:"GO:0051000"(positive regulation of nitric-oxide synthase activity)|go:"GO:0060314"(regulation of ryanodine-sensitive calcium-release channel activity)|go:"GO:1901339"(regulation of store-operated calcium channel activity)|go:"GO:1901841"(regulation of high voltage-gated calcium channel activity)|rcsb pdb:4I2Y|rcsb pdb:4IL1|go:"GO:0007190"(activation of adenylate cyclase activity)|go:"GO:0008179"(adenylate cyclase binding)|go:"GO:0019722"(calcium-mediated signaling)|go:"GO:0030235"(nitric-oxide synthase regulator activity)|rcsb pdb:4RJD|go:"GO:0000922"(spindle pole)|go:"GO:0005246"(calcium channel regulator activity)|rgd:2257|rgd:2258|rgd:2259|refseq:NP_036650.1|refseq:NP_059022.1|refseq:NP_114175.1|interpro:IPR011992(EF-Hand type)|interpro:IPR018247|interpro:IPR002048(Calcium-binding EF-hand)|rcsb pdb:1G4Y|rcsb pdb:1NIW|rcsb pdb:1QX5|rcsb pdb:1QX7|rcsb pdb:2HQW|rcsb pdb:2PQ3|rcsb pdb:3B32|rcsb pdb:3BXK|rcsb pdb:3BXL|rcsb pdb:3CLN|rcsb pdb:3EK4|rcsb pdb:3EK7|rcsb pdb:3EK8|rcsb pdb:3EKH|rcsb pdb:3EKJ|rcsb pdb:3EVR|rcsb pdb:3EVU|rcsb pdb:3EVV|rcsb pdb:3IFK|rcsb pdb:3SG2|rcsb pdb:3SG3|rcsb pdb:3SG4|rcsb pdb:3SG5|rcsb pdb:3SG6|rcsb pdb:3SG7|rcsb pdb:3SJQ|rcsb pdb:4QNH|go:"GO:0005509"(calcium ion binding)|reactome:R-RNO-2672351|reactome:R-RNO-418359|reactome:R-RNO-425561|reactome:R-RNO-5576892|reactome:R-RNO-5578775|reactome:R-RNO-936837|rcsb pdb:4OY4|go:"GO:0005829"(cytosol)|rcsb pdb:2YGG|go:"GO:0005886"(plasma membrane)|go:"GO:0002027"(regulation of heart rate)|go:"GO:0005513"(detection of calcium ion)|go:"GO:0005813"(centrosome)|go:"GO:0005876"(spindle microtubule)|go:"GO:0010880"(regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum)|go:"GO:0021762"(substantia nigra development)|go:"GO:0030017"(sarcomere)|go:"GO:0032465"(regulation of cytokinesis)|go:"GO:0032516"(positive regulation of phosphoprotein phosphatase activity)|go:"GO:0034704"(calcium channel complex)|go:"GO:0051343"(positive regulation of cyclic-nucleotide phosphodiesterase activity)|go:"GO:0055117"(regulation of cardiac muscle contraction)|go:"GO:0060316"(positive regulation of ryanodine-sensitive calcium-release channel activity)|go:"GO:0070062"(extracellular exosome)|go:"GO:0072542"(protein phosphatase activator activity)|go:"GO:0014069"(postsynaptic density)|go:"GO:0099566"(regulation of postsynaptic cytosolic calcium ion concentration)|reactome:R-RNO-8876725|go:"GO:0001975"(response to amphetamine)|go:"GO:0051412"(response to corticosterone)|rcsb pdb:4EHQ|rcsb pdb:4J9Y|rcsb pdb:4J9Z|reactome:R-RNO-163615|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030234"(enzyme regulator activity)|go:"GO:0031800"(type 3 metabotropic glutamate receptor binding)|go:"GO:0043005"(neuron projection)|go:"GO:0043548"(phosphatidylinositol 3-kinase binding)|go:"GO:0048306"(calcium-dependent protein binding)|rcsb pdb:2MGU|ensembl:ENSRNOT00000022603|ensembl:ENSRNOT00000064679|rcsb pdb:3WLC|rcsb pdb:3WLD|reactome:R-RNO-111932|reactome:R-RNO-111933|reactome:R-RNO-111957|reactome:R-RNO-114608|reactome:R-RNO-1474151|reactome:R-RNO-1855204|reactome:R-RNO-203615|reactome:R-RNO-2514859|reactome:R-RNO-2871809|reactome:R-RNO-4086398|reactome:R-RNO-442717|reactome:R-RNO-442729|reactome:R-RNO-442745|reactome:R-RNO-442982|reactome:R-RNO-445355|reactome:R-RNO-451308|reactome:R-RNO-5218920|reactome:R-RNO-5607763|reactome:R-RNO-5626467|reactome:R-RNO-5627123|reactome:R-RNO-5673001|reactome:R-RNO-70221|ensembl:ENSRNOG00000004060|ensembl:ENSRNOG00000016770|ensembl:ENSRNOP00000022603|ensembl:ENSRNOP00000063822|go:"GO:0008076"(voltage-gated potassium channel complex)|go:"GO:0000086"(G2/M transition of mitotic cell cycle)|go:"GO:0043388"(positive regulation of DNA binding)|go:"GO:0019855"(calcium channel inhibitor activity)|go:"GO:0060315"(negative regulation of ryanodine-sensitive calcium-release channel activity)	-	-	-	figure legend:ST1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10116(rat-brain-cerebellum)|taxid:10116(Rattus norvegicus)	-	2020/10/30	2020/10/30	rogid:DtE+ZXAZKdCMvUW5K+jXQ5bH07M10116	rogid:tTYcOd9bOh211njZVz7cYVybAMQ10116	rigid:OaXQ9NA25fwCWxejPU3Ao9q5j/E	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q5XIE8	uniprotkb:P55068	intact:EBI-15348306|ensembl:ENSRNOP00000023037	intact:EBI-26438001|uniprotkb:Q62860|uniprotkb:Q63040|uniprotkb:Q63513	psi-mi:itm2b_rat(display_long)|uniprotkb:Itm2b(gene name)|psi-mi:Itm2b(display_short)|uniprotkb:Immature BRI2(gene name synonym)|uniprotkb:Transmembrane protein BRI(gene name synonym)	psi-mi:pgcb_rat(display_long)|uniprotkb:Bcan(gene name)|psi-mi:Bcan(display_short)|uniprotkb:Behab(gene name synonym)|uniprotkb:Brain-enriched hyaluronan-binding protein(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Martins et al. (2018)	imex:IM-28469|pubmed:29476059	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26438079|imex:IM-28469-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSRNOG00000016271(gene)|ensembl:ENSRNOT00000023037(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001540"(amyloid-beta binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0010008"(endosome membrane)|go:"GO:0030660"(Golgi-associated vesicle membrane)|go:"GO:0031301"(integral component of organelle membrane)|go:"GO:0042985"(negative regulation of amyloid precursor protein biosynthetic process)|interpro:IPR007084(BRICHOS)|interpro:IPR040145|mint:Q5XIE8|refseq:NP_001006964.1|rgd:620727	go:"GO:0001501"(skeletal system development)|go:"GO:0005540"(hyaluronic acid binding)|go:"GO:0005615"(extracellular space)|go:"GO:0007160"(cell-matrix adhesion)|go:"GO:0007417"(central nervous system development)|go:"GO:0007420"(brain development)|go:"GO:0009986"(cell surface)|go:"GO:0021766"(hippocampus development)|go:"GO:0030246"(carbohydrate binding)|go:"GO:0030424"(axon)|go:"GO:0030425"(dendrite)|go:"GO:0031012"(extracellular matrix)|go:"GO:0031225"(anchored component of membrane)|go:"GO:0033268"(node of Ranvier)|go:"GO:0042063"(gliogenesis)|go:"GO:0043194"(axon initial segment)|go:"GO:0045202"(synapse)|go:"GO:0048168"(regulation of neuronal synaptic plasticity)|go:"GO:0060074"(synapse maturation)|go:"GO:0072534"(perineuronal net)|go:"GO:0098966"(perisynaptic extracellular matrix)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0098982"(GABA-ergic synapse)|go:"GO:1990138"(neuron projection extension)|reactome:R-RNO-1474228|reactome:R-RNO-1971475|reactome:R-RNO-2022870|reactome:R-RNO-2022923|reactome:R-RNO-2024101|reactome:R-RNO-3000178|mint:P55068|refseq:NP_001028837.1|refseq:NP_037048.2|interpro:IPR001304(C-type lectin)|interpro:IPR016186(C-type lectin-like)|interpro:IPR018378|interpro:IPR016187(C-type lectin fold)|interpro:IPR000742(EGF-like, type 3)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR036179|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR003006(Immunoglobulin/major histocompatibility complex, conserved site)|interpro:IPR003599(Immunoglobulin subtype)|interpro:IPR013106(Immunoglobulin V-set)|interpro:IPR000538(Link)|interpro:IPR035976|interpro:IPR000436(Sushi/SCR/CCP)|rgd:2194	-	-	-	figure legend:ST1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10116(rat-brain-cerebellum)|taxid:10116(Rattus norvegicus)	-	2020/10/30	2020/10/30	rogid:DtE+ZXAZKdCMvUW5K+jXQ5bH07M10116	rogid:lF9PzbTBUsVJ4tGND2U0A/3v3aY10116	rigid:OaXQ9NA25fwCWxejPU3Ao9q5j/E	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q5XIE8	uniprotkb:Q6PDU7	intact:EBI-15348306|ensembl:ENSRNOP00000023037	intact:EBI-2255888|uniprotkb:G3V9A9|ensembl:ENSRNOP00000040969	psi-mi:itm2b_rat(display_long)|uniprotkb:Itm2b(gene name)|psi-mi:Itm2b(display_short)|uniprotkb:Immature BRI2(gene name synonym)|uniprotkb:Transmembrane protein BRI(gene name synonym)	psi-mi:atp5l_rat(display_long)|uniprotkb:Atp5mg(gene name)|psi-mi:Atp5mg(display_short)|uniprotkb:ATP synthase membrane subunit g(gene name synonym)|uniprotkb:Atp5l(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Martins et al. (2018)	imex:IM-28469|pubmed:29476059	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26438079|imex:IM-28469-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSRNOG00000016271(gene)|ensembl:ENSRNOT00000023037(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001540"(amyloid-beta binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0010008"(endosome membrane)|go:"GO:0030660"(Golgi-associated vesicle membrane)|go:"GO:0031301"(integral component of organelle membrane)|go:"GO:0042985"(negative regulation of amyloid precursor protein biosynthetic process)|interpro:IPR007084(BRICHOS)|interpro:IPR040145|mint:Q5XIE8|refseq:NP_001006964.1|rgd:620727	rgd:1303259|refseq:NP_997681.1|ensembl:ENSRNOG00000028884(gene)|ensembl:ENSRNOT00000050878(transcript)|go:"GO:0000276"("mitochondrial proton-transporting ATP synthase complex, coupling factor F(o)")|go:"GO:0005753"(mitochondrial proton-transporting ATP synthase complex)|go:"GO:0015078"(proton transmembrane transporter activity)|go:"GO:0015986"(ATP synthesis coupled proton transport)|go:"GO:0042776"(mitochondrial ATP synthesis coupled proton transport)|go:"GO:0046034"(ATP metabolic process)|interpro:IPR006808(ATPase, F0 complex, subunit G, mitochondrial)|interpro:IPR016702(Mitochondrial ATP synthase subunit g, animal)|mint:Q6PDU7|reactome:R-RNO-163210|reactome:R-RNO-8949613	-	-	-	figure legend:ST1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10116(rat-brain-cerebellum)|taxid:10116(Rattus norvegicus)	-	2020/10/30	2020/10/30	rogid:DtE+ZXAZKdCMvUW5K+jXQ5bH07M10116	rogid:z3KVnfCKanB5KSzgEuxsY4pAlds10116	rigid:OaXQ9NA25fwCWxejPU3Ao9q5j/E	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q5XIE8	uniprotkb:D3ZAF6	intact:EBI-15348306|ensembl:ENSRNOP00000023037	intact:EBI-26437983|ensembl:ENSRNOP00000029426	psi-mi:itm2b_rat(display_long)|uniprotkb:Itm2b(gene name)|psi-mi:Itm2b(display_short)|uniprotkb:Immature BRI2(gene name synonym)|uniprotkb:Transmembrane protein BRI(gene name synonym)	psi-mi:atpk_rat(display_long)|uniprotkb:Atp5mf(gene name)|psi-mi:Atp5mf(display_short)|uniprotkb:Atp5j2(gene name synonym)|uniprotkb:ATP synthase membrane subunit f(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Martins et al. (2018)	imex:IM-28469|pubmed:29476059	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26438079|imex:IM-28469-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSRNOG00000016271(gene)|ensembl:ENSRNOT00000023037(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001540"(amyloid-beta binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0010008"(endosome membrane)|go:"GO:0030660"(Golgi-associated vesicle membrane)|go:"GO:0031301"(integral component of organelle membrane)|go:"GO:0042985"(negative regulation of amyloid precursor protein biosynthetic process)|interpro:IPR007084(BRICHOS)|interpro:IPR040145|mint:Q5XIE8|refseq:NP_001006964.1|rgd:620727	ensembl:ENSRNOG00000027049(gene)|ensembl:ENSRNOT00000033537(transcript)|go:"GO:0000276"("mitochondrial proton-transporting ATP synthase complex, coupling factor F(o)")|go:"GO:0005753"(mitochondrial proton-transporting ATP synthase complex)|go:"GO:0016021"(integral component of membrane)|go:"GO:0031965"(nuclear membrane)|go:"GO:0042776"(mitochondrial ATP synthesis coupled proton transport)|go:"GO:0046034"(ATP metabolic process)|go:"GO:0046933"(proton-transporting ATP synthase activity, rotational mechanism)|interpro:IPR019344|mint:D3ZAF6|reactome:R-RNO-163210|reactome:R-RNO-8949613|refseq:NP_001258046.1|rgd:1596067	-	-	-	figure legend:ST1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10116(rat-brain-cerebellum)|taxid:10116(Rattus norvegicus)	-	2020/10/30	2020/10/30	rogid:DtE+ZXAZKdCMvUW5K+jXQ5bH07M10116	rogid:vcwbNZR75EcqIXL/9z6Qw/Fyml810116	rigid:OaXQ9NA25fwCWxejPU3Ao9q5j/E	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q5XIE8	uniprotkb:P54921	intact:EBI-15348306|ensembl:ENSRNOP00000023037	intact:EBI-917790|ensembl:ENSRNOP00000002044	psi-mi:itm2b_rat(display_long)|uniprotkb:Itm2b(gene name)|psi-mi:Itm2b(display_short)|uniprotkb:Immature BRI2(gene name synonym)|uniprotkb:Transmembrane protein BRI(gene name synonym)	psi-mi:snaa_rat(display_long)|uniprotkb:N-ethylmaleimide-sensitive factor attachment protein alpha(gene name synonym)|uniprotkb:Napa(gene name)|psi-mi:Napa(display_short)|uniprotkb:Snap(gene name synonym)|uniprotkb:Snapa(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Martins et al. (2018)	imex:IM-28469|pubmed:29476059	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26438079|imex:IM-28469-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSRNOG00000016271(gene)|ensembl:ENSRNOT00000023037(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001540"(amyloid-beta binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0010008"(endosome membrane)|go:"GO:0030660"(Golgi-associated vesicle membrane)|go:"GO:0031301"(integral component of organelle membrane)|go:"GO:0042985"(negative regulation of amyloid precursor protein biosynthetic process)|interpro:IPR007084(BRICHOS)|interpro:IPR040145|mint:Q5XIE8|refseq:NP_001006964.1|rgd:620727	rgd:620855|refseq:NP_542152.1|dip:DIP-37030N|ensembl:ENSRNOG00000001494(gene)|ensembl:ENSRNOT00000002044(transcript)|go:"GO:0000149"(SNARE binding)|go:"GO:0005483"(soluble NSF attachment protein activity)|go:"GO:0005774"(vacuolar membrane)|go:"GO:0005886"(plasma membrane)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0007420"(brain development)|go:"GO:0010807"(regulation of synaptic vesicle priming)|go:"GO:0016082"(synaptic vesicle priming)|go:"GO:0019905"(syntaxin binding)|go:"GO:0030182"(neuron differentiation)|go:"GO:0031201"(SNARE complex)|go:"GO:0032781"(positive regulation of ATP-dependent activity)|go:"GO:0032984"(protein-containing complex disassembly)|go:"GO:0035249"(synaptic transmission, glutamatergic)|go:"GO:0035494"(SNARE complex disassembly)|go:"GO:0043195"(terminal bouton)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045176"(apical protein localization)|go:"GO:0061025"(membrane fusion)|go:"GO:0070044"(synaptobrevin 2-SNAP-25-syntaxin-1a complex)|go:"GO:0098793"(presynapse)|go:"GO:0098794"(postsynapse)|go:"GO:0098978"(glutamatergic synapse)|interpro:IPR000744(NSF attachment protein)|interpro:IPR011990(Tetratricopeptide-like helical)|mint:P54921|rcsb pdb:3J96|rcsb pdb:3J97|rcsb pdb:3J98|rcsb pdb:3J99|rcsb pdb:6MDM|rcsb pdb:6MDN|reactome:R-RNO-204005|reactome:R-RNO-432722|reactome:R-RNO-6807878|reactome:R-RNO-6811434|reactome:R-RNO-6811438|reactome:R-RNO-6811440	-	-	-	figure legend:ST1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10116(rat-brain-cerebellum)|taxid:10116(Rattus norvegicus)	-	2020/10/30	2020/10/30	rogid:DtE+ZXAZKdCMvUW5K+jXQ5bH07M10116	rogid:+Lm6fLpvZFjClv3xfc066b0H2Gc10116	rigid:OaXQ9NA25fwCWxejPU3Ao9q5j/E	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q5XIE8	uniprotkb:Q63028	intact:EBI-15348306|ensembl:ENSRNOP00000023037	intact:EBI-26437931|uniprotkb:Q3B7D4|uniprotkb:Q64722	psi-mi:itm2b_rat(display_long)|uniprotkb:Itm2b(gene name)|psi-mi:Itm2b(display_short)|uniprotkb:Immature BRI2(gene name synonym)|uniprotkb:Transmembrane protein BRI(gene name synonym)	psi-mi:adda_rat(display_long)|uniprotkb:Add1(gene name)|psi-mi:Add1(display_short)|uniprotkb:Erythrocyte adducin subunit alpha(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Martins et al. (2018)	imex:IM-28469|pubmed:29476059	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26438079|imex:IM-28469-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSRNOG00000016271(gene)|ensembl:ENSRNOT00000023037(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001540"(amyloid-beta binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0010008"(endosome membrane)|go:"GO:0030660"(Golgi-associated vesicle membrane)|go:"GO:0031301"(integral component of organelle membrane)|go:"GO:0042985"(negative regulation of amyloid precursor protein biosynthetic process)|interpro:IPR007084(BRICHOS)|interpro:IPR040145|mint:Q5XIE8|refseq:NP_001006964.1|rgd:620727	go:"GO:0000902"(cell morphogenesis)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0005200"(structural constituent of cytoskeleton)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005886"(plasma membrane)|go:"GO:0005912"(adherens junction)|go:"GO:0006811"(ion transport)|go:"GO:0006884"(cell volume homeostasis)|go:"GO:0007010"(cytoskeleton organization)|go:"GO:0008290"(F-actin capping protein complex)|go:"GO:0014069"(postsynaptic density)|go:"GO:0016020"(membrane)|go:"GO:0020027"(hemoglobin metabolic process)|go:"GO:0030218"(erythrocyte differentiation)|go:"GO:0030425"(dendrite)|go:"GO:0030507"(spectrin binding)|go:"GO:0030837"(negative regulation of actin filament polymerization)|go:"GO:0032092"(positive regulation of protein binding)|go:"GO:0035264"(multicellular organism growth)|go:"GO:0042608"(T cell receptor binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043197"(dendritic spine)|go:"GO:0045202"(synapse)|go:"GO:0045766"(positive regulation of angiogenesis)|go:"GO:0045807"(positive regulation of endocytosis)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0048873"(homeostasis of number of cells within a tissue)|go:"GO:0051015"(actin filament binding)|go:"GO:0051016"(barbed-end actin filament capping)|go:"GO:0051017"(actin filament bundle assembly)|go:"GO:0071277"(cellular response to calcium ion)|go:"GO:0071300"(cellular response to retinoic acid)|go:"GO:1903142"(positive regulation of establishment of endothelial barrier)|go:"GO:1903393"(positive regulation of adherens junction organization)|reactome:R-RNO-264870|reactome:R-RNO-5223345|mint:Q63028|refseq:NP_058686.2|interpro:IPR027766|interpro:IPR001303(Class II aldolase/adducin, N-terminal)|interpro:IPR036409|rgd:2041	-	-	-	figure legend:ST1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10116(rat-brain-cerebellum)|taxid:10116(Rattus norvegicus)	-	2020/10/30	2020/10/30	rogid:DtE+ZXAZKdCMvUW5K+jXQ5bH07M10116	rogid:T27XZNiVX2+OqOG0UuPsYWGSUT810116	rigid:OaXQ9NA25fwCWxejPU3Ao9q5j/E	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q5XIE8	uniprotkb:Q9Z270	intact:EBI-15348306|ensembl:ENSRNOP00000023037	intact:EBI-2909425|ensembl:ENSRNOP00000020681|uniprotkb:Q6P723	psi-mi:itm2b_rat(display_long)|uniprotkb:Itm2b(gene name)|psi-mi:Itm2b(display_short)|uniprotkb:Immature BRI2(gene name synonym)|uniprotkb:Transmembrane protein BRI(gene name synonym)	psi-mi:vapa_rat(display_long)|uniprotkb:Vapa(gene name)|psi-mi:Vapa(display_short)|uniprotkb:Vap33(gene name synonym)|uniprotkb:33 kDa VAMP-associated protein(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Martins et al. (2018)	imex:IM-28469|pubmed:29476059	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26438079|imex:IM-28469-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSRNOG00000016271(gene)|ensembl:ENSRNOT00000023037(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001540"(amyloid-beta binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0010008"(endosome membrane)|go:"GO:0030660"(Golgi-associated vesicle membrane)|go:"GO:0031301"(integral component of organelle membrane)|go:"GO:0042985"(negative regulation of amyloid precursor protein biosynthetic process)|interpro:IPR007084(BRICHOS)|interpro:IPR040145|mint:Q5XIE8|refseq:NP_001006964.1|rgd:620727	ensembl:ENSRNOG00000014765(gene)|ensembl:ENSRNOT00000020681(transcript)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005886"(plasma membrane)|go:"GO:0005923"(bicellular tight junction)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0008017"(microtubule binding)|go:"GO:0008219"(cell death)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0031175"(neuron projection development)|go:"GO:0031965"(nuclear membrane)|go:"GO:0031982"(vesicle)|go:"GO:0033149"(FFAT motif binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0044791"(obsolete positive regulation by host of viral release from host cell)|go:"GO:0044828"(negative regulation by host of viral genome replication)|go:"GO:0044829"(positive regulation by host of viral genome replication)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0070972"(protein localization to endoplasmic reticulum)|go:"GO:0090114"(COPII-coated vesicle budding)|interpro:IPR000535(Major sperm protein)|interpro:IPR008962(PapD-like)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR016763(Vesicle-associated membrane protein)|mint:Q9Z270|rcsb pdb:1Z9L|rcsb pdb:1Z9O|reactome:R-RNO-1660661|reactome:R-RNO-6798695|reactome:R-RNO-9609523|go:"GO:0046982"(protein heterodimerization activity)|rgd:61803|refseq:NP_113819.3|dip:DIP-48448N	-	-	-	figure legend:ST1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10116(rat-brain-cerebellum)|taxid:10116(Rattus norvegicus)	-	2020/10/30	2020/10/30	rogid:DtE+ZXAZKdCMvUW5K+jXQ5bH07M10116	rogid:ZMxTb0ZumI4k+ZOZbfLLapSngf810116	rigid:OaXQ9NA25fwCWxejPU3Ao9q5j/E	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q5XIE8	uniprotkb:P19234	intact:EBI-15348306|ensembl:ENSRNOP00000023037	intact:EBI-916768|uniprotkb:Q6PDU9|ensembl:ENSRNOP00000016965	psi-mi:itm2b_rat(display_long)|uniprotkb:Itm2b(gene name)|psi-mi:Itm2b(display_short)|uniprotkb:Immature BRI2(gene name synonym)|uniprotkb:Transmembrane protein BRI(gene name synonym)	psi-mi:nduv2_rat(display_long)|uniprotkb:NADH-ubiquinone oxidoreductase 24 kDa subunit(gene name synonym)|uniprotkb:Ndufv2(gene name)|psi-mi:Ndufv2(display_short)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Martins et al. (2018)	imex:IM-28469|pubmed:29476059	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26438079|imex:IM-28469-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSRNOG00000016271(gene)|ensembl:ENSRNOT00000023037(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001540"(amyloid-beta binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0010008"(endosome membrane)|go:"GO:0030660"(Golgi-associated vesicle membrane)|go:"GO:0031301"(integral component of organelle membrane)|go:"GO:0042985"(negative regulation of amyloid precursor protein biosynthetic process)|interpro:IPR007084(BRICHOS)|interpro:IPR040145|mint:Q5XIE8|refseq:NP_001006964.1|rgd:620727	rgd:621733|refseq:NP_112326.1|ensembl:ENSRNOG00000042503(gene)|ensembl:ENSRNOT00000016965(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005747"(mitochondrial respiratory chain complex I)|go:"GO:0005829"(cytosol)|go:"GO:0006120"(mitochondrial electron transport, NADH to ubiquinone)|go:"GO:0007399"(nervous system development)|go:"GO:0008137"("NADH dehydrogenase (ubiquinone) activity")|go:"GO:0046872"(metal ion binding)|go:"GO:0048738"(cardiac muscle tissue development)|go:"GO:0051537"(2 iron, 2 sulfur cluster binding)|interpro:IPR002023("NADH dehydrogenase (ubiquinone), 24 kDa subunit")|interpro:IPR036249|interpro:IPR041921|interpro:IPR042128|mint:P19234|reactome:R-RNO-611105|reactome:R-RNO-6799198	-	-	-	figure legend:ST1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10116(rat-brain-cerebellum)|taxid:10116(Rattus norvegicus)	-	2020/10/30	2020/10/30	rogid:DtE+ZXAZKdCMvUW5K+jXQ5bH07M10116	rogid:DJh8LBV775oK8nsimzcy05KUBRg10116	rigid:OaXQ9NA25fwCWxejPU3Ao9q5j/E	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q5XIE8	uniprotkb:Q01986	intact:EBI-15348306|ensembl:ENSRNOP00000023037	intact:EBI-26373480|uniprotkb:Q5EBD5	psi-mi:itm2b_rat(display_long)|uniprotkb:Itm2b(gene name)|psi-mi:Itm2b(display_short)|uniprotkb:Immature BRI2(gene name synonym)|uniprotkb:Transmembrane protein BRI(gene name synonym)	psi-mi:mp2k1_rat(display_long)|uniprotkb:ERK activator kinase 1(gene name synonym)|uniprotkb:MAPK/ERK kinase 1(gene name synonym)|uniprotkb:Map2k1(gene name)|psi-mi:Map2k1(display_short)|uniprotkb:Mek1(gene name synonym)|uniprotkb:Prkmk1(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Martins et al. (2018)	imex:IM-28469|pubmed:29476059	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26438079|imex:IM-28469-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSRNOG00000016271(gene)|ensembl:ENSRNOT00000023037(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001540"(amyloid-beta binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0010008"(endosome membrane)|go:"GO:0030660"(Golgi-associated vesicle membrane)|go:"GO:0031301"(integral component of organelle membrane)|go:"GO:0042985"(negative regulation of amyloid precursor protein biosynthetic process)|interpro:IPR007084(BRICHOS)|interpro:IPR040145|mint:Q5XIE8|refseq:NP_001006964.1|rgd:620727	go:"GO:0060502"(epithelial cell proliferation involved in lung morphogenesis)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0060674"(placenta blood vessel development)|go:"GO:0060711"(labyrinthine layer development)|go:"GO:0070328"(triglyceride homeostasis)|go:"GO:0070371"(ERK1 and ERK2 cascade)|go:"GO:0070372"(regulation of ERK1 and ERK2 cascade)|go:"GO:0070374"(positive regulation of ERK1 and ERK2 cascade)|go:"GO:0106311"|go:"GO:1903298"(negative regulation of hypoxia-induced intrinsic apoptotic signaling pathway)|go:"GO:1903800"(positive regulation of production of miRNAs involved in gene silencing by miRNA)|go:"GO:2000641"(regulation of early endosome to late endosome transport)|go:"GO:0071902"(positive regulation of protein serine/threonine kinase activity)|go:"GO:0090170"(regulation of Golgi inheritance)|go:"GO:2001171"(positive regulation of ATP biosynthetic process)|go:"GO:0090398"(cellular senescence)|go:"GO:0097110"(scaffold protein binding)|go:"GO:0098696"(regulation of neurotransmitter receptor localization to postsynaptic specialization membrane)|reactome:R-RNO-110056|reactome:R-RNO-170968|reactome:R-RNO-445144|reactome:R-RNO-5673000|reactome:R-RNO-5674135|reactome:R-RNO-5674499|go:"GO:0000187"(obsolete activation of MAPK activity)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0003056"(regulation of vascular associated smooth muscle contraction)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0004708"(MAP kinase kinase activity)|go:"GO:0004712"(protein serine/threonine/tyrosine kinase activity)|go:"GO:0004714"(transmembrane receptor protein tyrosine kinase activity)|go:"GO:0005078"(MAP-kinase scaffold activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005739"(mitochondrion)|go:"GO:0005769"(early endosome)|go:"GO:0005770"(late endosome)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005815"(microtubule organizing center)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005925"(focal adhesion)|go:"GO:0005938"(cell cortex)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0006979"(response to oxidative stress)|go:"GO:0007507"(heart development)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008283"(cell population proliferation)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0010508"(positive regulation of autophagy)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0014069"(postsynaptic density)|go:"GO:0018107"(peptidyl-threonine phosphorylation)|go:"GO:0019901"(protein kinase binding)|go:"GO:0021697"(cerebellar cortex formation)|go:"GO:0030182"(neuron differentiation)|go:"GO:0030216"(keratinocyte differentiation)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0030424"(axon)|go:"GO:0030425"(dendrite)|go:"GO:0030878"(thyroid gland development)|go:"GO:0031267"(small GTPase binding)|go:"GO:0031435"(mitogen-activated protein kinase kinase kinase binding)|go:"GO:0032402"(melanosome transport)|go:"GO:0032839"(dendrite cytoplasm)|go:"GO:0032872"(regulation of stress-activated MAPK cascade)|go:"GO:0032968"(positive regulation of transcription elongation from RNA polymerase II promoter)|go:"GO:0034111"(negative regulation of homotypic cell-cell adhesion)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0042593"(glucose homeostasis)|go:"GO:0043204"(perikaryon)|go:"GO:0043539"(protein serine/threonine kinase activator activity)|go:"GO:0043547"(positive regulation of GTPase activity)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045597"(positive regulation of cell differentiation)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045933"(positive regulation of muscle contraction)|go:"GO:0046579"(positive regulation of Ras protein signal transduction)|go:"GO:0047485"(protein N-terminus binding)|go:"GO:0047496"(vesicle transport along microtubule)|go:"GO:0048313"(Golgi inheritance)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0048538"(thymus development)|go:"GO:0048678"(response to axon injury)|go:"GO:0048679"(regulation of axon regeneration)|go:"GO:0048812"(neuron projection morphogenesis)|go:"GO:0048870"(cell motility)|go:"GO:0050772"(positive regulation of axonogenesis)|go:"GO:0051384"(response to glucocorticoid)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0060020"(Bergmann glial cell differentiation)|go:"GO:0060324"(face development)|go:"GO:0060425"(lung morphogenesis)|go:"GO:0060440"(trachea formation)|rgd:70495|mint:Q01986|refseq:NP_113831.1|interpro:IPR011009(Protein kinase-like)|interpro:IPR000719(Protein kinase, core)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR008271(Serine/threonine protein kinase, active site)	-	-	-	figure legend:ST1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10116(rat-brain-cerebellum)|taxid:10116(Rattus norvegicus)	-	2020/10/30	2020/10/30	rogid:DtE+ZXAZKdCMvUW5K+jXQ5bH07M10116	rogid:XblxWneV7tc/8bwEVlk103FIRCg10116	rigid:OaXQ9NA25fwCWxejPU3Ao9q5j/E	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q5XIE8	uniprotkb:Q561S0	intact:EBI-15348306|ensembl:ENSRNOP00000023037	intact:EBI-22250632|ensembl:ENSRNOP00000022089|uniprotkb:Q80WE0	psi-mi:itm2b_rat(display_long)|uniprotkb:Itm2b(gene name)|psi-mi:Itm2b(display_short)|uniprotkb:Immature BRI2(gene name synonym)|uniprotkb:Transmembrane protein BRI(gene name synonym)	psi-mi:nduaa_rat(display_long)|uniprotkb:Complex I-42kD(gene name synonym)|uniprotkb:NADH-ubiquinone oxidoreductase 42 kDa subunit(gene name synonym)|uniprotkb:Ndufa10(gene name)|psi-mi:Ndufa10(display_short)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Martins et al. (2018)	imex:IM-28469|pubmed:29476059	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26438079|imex:IM-28469-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSRNOG00000016271(gene)|ensembl:ENSRNOT00000023037(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001540"(amyloid-beta binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0010008"(endosome membrane)|go:"GO:0030660"(Golgi-associated vesicle membrane)|go:"GO:0031301"(integral component of organelle membrane)|go:"GO:0042985"(negative regulation of amyloid precursor protein biosynthetic process)|interpro:IPR007084(BRICHOS)|interpro:IPR040145|mint:Q5XIE8|refseq:NP_001006964.1|rgd:620727	ensembl:ENSRNOG00000016470(gene)|ensembl:ENSRNOT00000022089(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0005747"(mitochondrial respiratory chain complex I)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0006120"(mitochondrial electron transport, NADH to ubiquinone)|go:"GO:0008137"("NADH dehydrogenase (ubiquinone) activity")|go:"GO:0032981"(mitochondrial respiratory chain complex I assembly)|go:"GO:0042493"|interpro:IPR015828(NADH-ubiquinone oxidoreductase, 42 kDa subunit)|interpro:IPR027417|interpro:IPR031314|reactome:R-RNO-611105|reactome:R-RNO-6799198|mint:Q561S0|refseq:NP_872612.1|refseq:NP_955789.2|rgd:727968	-	-	-	figure legend:ST1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10116(rat-brain-cerebellum)|taxid:10116(Rattus norvegicus)	-	2020/10/30	2020/10/30	rogid:DtE+ZXAZKdCMvUW5K+jXQ5bH07M10116	rogid:WdH5x1mQ7WuKYu6aBc3neTbxYOY10116	rigid:OaXQ9NA25fwCWxejPU3Ao9q5j/E	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q5XIE8	uniprotkb:P08413	intact:EBI-15348306|ensembl:ENSRNOP00000023037	intact:EBI-916155	psi-mi:itm2b_rat(display_long)|uniprotkb:Itm2b(gene name)|psi-mi:Itm2b(display_short)|uniprotkb:Immature BRI2(gene name synonym)|uniprotkb:Transmembrane protein BRI(gene name synonym)	psi-mi:kcc2b_rat(display_long)|uniprotkb:Camk2b(gene name)|psi-mi:Camk2b(display_short)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Martins et al. (2018)	imex:IM-28469|pubmed:29476059	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26438079|imex:IM-28469-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSRNOG00000016271(gene)|ensembl:ENSRNOT00000023037(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001540"(amyloid-beta binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0010008"(endosome membrane)|go:"GO:0030660"(Golgi-associated vesicle membrane)|go:"GO:0031301"(integral component of organelle membrane)|go:"GO:0042985"(negative regulation of amyloid precursor protein biosynthetic process)|interpro:IPR007084(BRICHOS)|interpro:IPR040145|mint:Q5XIE8|refseq:NP_001006964.1|rgd:620727	rgd:2262|refseq:NP_001035815.1|refseq:NP_068507.2|go:"GO:0000082"(G1/S transition of mitotic cell cycle)|go:"GO:0002030"(inhibitory G protein-coupled receptor phosphorylation)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0004683"(calmodulin-dependent protein kinase activity)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005815"(microtubule organizing center)|go:"GO:0005829"(cytosol)|go:"GO:0005954"(calcium- and calmodulin-dependent protein kinase complex)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:0110088"(hippocampal neuron apoptotic process)|go:"GO:0006816"(calcium ion transport)|go:"GO:0010976"(positive regulation of neuron projection development)|go:"GO:0014069"(postsynaptic density)|go:"GO:0018105"(peptidyl-serine phosphorylation)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030425"(dendrite)|go:"GO:0032222"(regulation of synaptic transmission, cholinergic)|go:"GO:0032430"(positive regulation of phospholipase A2 activity)|go:"GO:0033017"(sarcoplasmic reticulum membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043005"(neuron projection)|go:"GO:0043204"(perikaryon)|go:"GO:0043274"(phospholipase binding)|go:"GO:0046686"(response to cadmium ion)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0048169"(regulation of long-term neuronal synaptic plasticity)|go:"GO:0048858"(cell projection morphogenesis)|go:"GO:0050885"(neuromuscular process controlling balance)|go:"GO:0051233"(spindle midzone)|go:"GO:0060291"(long-term synaptic potentiation)|go:"GO:0060466"(activation of meiosis involved in egg activation)|go:"GO:0061003"(positive regulation of dendritic spine morphogenesis)|go:"GO:0090129"(positive regulation of synapse maturation)|go:"GO:0098973"(structural constituent of postsynaptic actin cytoskeleton)|reactome:R-RNO-5578775|reactome:R-RNO-5673000|reactome:R-RNO-5673001|reactome:R-RNO-877300|reactome:R-RNO-936837|mint:P08413|go:"GO:1903076"(regulation of protein localization to plasma membrane)|go:"GO:1905375"(cellular response to homocysteine)|go:"GO:1990911"(response to psychosocial stress)|go:"GO:2001222"(regulation of neuron migration)|go:"GO:2001235"(positive regulation of apoptotic signaling pathway)|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR013543(Calcium/calmodulin dependent protein kinase II, association-domain)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR032710|rcsb pdb:6HCS|reactome:R-RNO-3371571|reactome:R-RNO-399719|reactome:R-RNO-438066|reactome:R-RNO-5576892|dip:DIP-36948N	-	-	-	figure legend:ST1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10116(rat-brain-cerebellum)|taxid:10116(Rattus norvegicus)	-	2020/10/30	2020/10/30	rogid:DtE+ZXAZKdCMvUW5K+jXQ5bH07M10116	rogid:RojSx9Ro3RlYG4LM8c8FroRaKzs10116	rigid:OaXQ9NA25fwCWxejPU3Ao9q5j/E	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q5XIE8	uniprotkb:Q66HR5	intact:EBI-15348306|ensembl:ENSRNOP00000023037	intact:EBI-26437895|ensembl:ENSRNOP00000021522|ensembl:ENSRNOP00000064554|uniprotkb:Q8R443	psi-mi:itm2b_rat(display_long)|uniprotkb:Itm2b(gene name)|psi-mi:Itm2b(display_short)|uniprotkb:Immature BRI2(gene name synonym)|uniprotkb:Transmembrane protein BRI(gene name synonym)	psi-mi:caco1_rat(display_long)|uniprotkb:Calcoco1(gene name)|psi-mi:Calcoco1(display_short)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Martins et al. (2018)	imex:IM-28469|pubmed:29476059	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26438079|imex:IM-28469-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSRNOG00000016271(gene)|ensembl:ENSRNOT00000023037(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001540"(amyloid-beta binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0010008"(endosome membrane)|go:"GO:0030660"(Golgi-associated vesicle membrane)|go:"GO:0031301"(integral component of organelle membrane)|go:"GO:0042985"(negative regulation of amyloid precursor protein biosynthetic process)|interpro:IPR007084(BRICHOS)|interpro:IPR040145|mint:Q5XIE8|refseq:NP_001006964.1|rgd:620727	ensembl:ENSRNOG00000015447(gene)|ensembl:ENSRNOG00000048982(gene)|ensembl:ENSRNOT00000021523(transcript)|ensembl:ENSRNOT00000070855(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0007165"(signal transduction)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0030374"(nuclear receptor coactivator activity)|go:"GO:0030518"(intracellular steroid hormone receptor signaling pathway)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|go:"GO:0070016"(armadillo repeat domain binding)|interpro:IPR012852(Coiled-coil transcriptional coactivator-like)|interpro:IPR041611|interpro:IPR041641|mint:Q66HR5|go:"GO:0016055"(Wnt signaling pathway)|refseq:NP_631929.1|refseq:XP_003750466.1|refseq:XP_017459014.1|rgd:619812	-	-	-	figure legend:ST1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10116(rat-brain-cerebellum)|taxid:10116(Rattus norvegicus)	-	2020/10/30	2020/10/30	rogid:DtE+ZXAZKdCMvUW5K+jXQ5bH07M10116	rogid:LlzzRDYh96ak+uCTha2DsL0T8BM10116	rigid:OaXQ9NA25fwCWxejPU3Ao9q5j/E	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q5XIE8	uniprotkb:P11730	intact:EBI-15348306|ensembl:ENSRNOP00000023037	intact:EBI-916359|uniprotkb:Q64003|uniprotkb:Q64004|ensembl:ENSRNOP00000062321	psi-mi:itm2b_rat(display_long)|uniprotkb:Itm2b(gene name)|psi-mi:Itm2b(display_short)|uniprotkb:Immature BRI2(gene name synonym)|uniprotkb:Transmembrane protein BRI(gene name synonym)	psi-mi:kcc2g_rat(display_long)|uniprotkb:Camk2g(gene name)|psi-mi:Camk2g(display_short)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Martins et al. (2018)	imex:IM-28469|pubmed:29476059	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26438079|imex:IM-28469-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSRNOG00000016271(gene)|ensembl:ENSRNOT00000023037(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001540"(amyloid-beta binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0010008"(endosome membrane)|go:"GO:0030660"(Golgi-associated vesicle membrane)|go:"GO:0031301"(integral component of organelle membrane)|go:"GO:0042985"(negative regulation of amyloid precursor protein biosynthetic process)|interpro:IPR007084(BRICHOS)|interpro:IPR040145|mint:Q5XIE8|refseq:NP_001006964.1|rgd:620727	rgd:621802|refseq:NP_598289.1|ensembl:ENSRNOG00000009783(gene)|ensembl:ENSRNOT00000066163(transcript)|go:"GO:0000082"(G1/S transition of mitotic cell cycle)|go:"GO:0001666"(response to hypoxia)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0004683"(calmodulin-dependent protein kinase activity)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005954"(calcium- and calmodulin-dependent protein kinase complex)|go:"GO:0006816"(calcium ion transport)|go:"GO:0006979"(response to oxidative stress)|go:"GO:0007399"(nervous system development)|go:"GO:0010975"(regulation of neuron projection development)|go:"GO:0014069"(postsynaptic density)|go:"GO:0030154"(cell differentiation)|go:"GO:0033017"(sarcoplasmic reticulum membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043005"(neuron projection)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0048169"(regulation of long-term neuronal synaptic plasticity)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:1901897"(regulation of relaxation of cardiac muscle)|go:"GO:1903076"(regulation of protein localization to plasma membrane)|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR013543(Calcium/calmodulin dependent protein kinase II, association-domain)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR032710|mint:P11730|reactome:R-RNO-3371571|reactome:R-RNO-399719|reactome:R-RNO-438066|reactome:R-RNO-5576892|reactome:R-RNO-5578775|reactome:R-RNO-5673000|reactome:R-RNO-5673001|reactome:R-RNO-877300|reactome:R-RNO-936837|refseq:XP_008768721.1	-	-	-	figure legend:ST1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10116(rat-brain-cerebellum)|taxid:10116(Rattus norvegicus)	-	2020/10/30	2020/10/30	rogid:DtE+ZXAZKdCMvUW5K+jXQ5bH07M10116	rogid:HFnqkrMFXXpL90nLx86YWIJ8z/810116	rigid:OaXQ9NA25fwCWxejPU3Ao9q5j/E	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q5XIE8	uniprotkb:P15791	intact:EBI-15348306|ensembl:ENSRNOP00000023037	intact:EBI-916602|uniprotkb:P97915|uniprotkb:P97916|uniprotkb:Q3B7L0|uniprotkb:Q63904|uniprotkb:Q63905|uniprotkb:Q63906|uniprotkb:Q63907|uniprotkb:Q63908|ensembl:ENSRNOP00000016026|ensembl:ENSRNOP00000062625	psi-mi:itm2b_rat(display_long)|uniprotkb:Itm2b(gene name)|psi-mi:Itm2b(display_short)|uniprotkb:Immature BRI2(gene name synonym)|uniprotkb:Transmembrane protein BRI(gene name synonym)	psi-mi:kcc2d_rat(display_long)|uniprotkb:Camk2d(gene name)|psi-mi:Camk2d(display_short)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Martins et al. (2018)	imex:IM-28469|pubmed:29476059	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26438079|imex:IM-28469-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSRNOG00000016271(gene)|ensembl:ENSRNOT00000023037(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001540"(amyloid-beta binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0010008"(endosome membrane)|go:"GO:0030660"(Golgi-associated vesicle membrane)|go:"GO:0031301"(integral component of organelle membrane)|go:"GO:0042985"(negative regulation of amyloid precursor protein biosynthetic process)|interpro:IPR007084(BRICHOS)|interpro:IPR040145|mint:Q5XIE8|refseq:NP_001006964.1|rgd:620727	rgd:2263|refseq:NP_036651.1|ensembl:ENSRNOG00000011589(gene)|ensembl:ENSRNOT00000016026(transcript)|ensembl:ENSRNOT00000068198(transcript)|go:"GO:0000082"(G1/S transition of mitotic cell cycle)|go:"GO:0001666"(response to hypoxia)|go:"GO:0002028"(regulation of sodium ion transport)|go:"GO:0003254"(regulation of membrane depolarization)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0004683"(calmodulin-dependent protein kinase activity)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005954"(calcium- and calmodulin-dependent protein kinase complex)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0006816"(calcium ion transport)|go:"GO:0010613"(positive regulation of cardiac muscle hypertrophy)|go:"GO:0010649"(regulation of cell communication by electrical coupling)|go:"GO:0010666"(positive regulation of cardiac muscle cell apoptotic process)|go:"GO:0010880"(regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum)|go:"GO:0010881"(regulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion)|go:"GO:0010971"(positive regulation of G2/M transition of mitotic cell cycle)|go:"GO:2000573"(positive regulation of DNA biosynthetic process)|go:"GO:0014704"(intercalated disc)|go:"GO:0014911"(positive regulation of smooth muscle cell migration)|go:"GO:0018105"(peptidyl-serine phosphorylation)|go:"GO:0018107"(peptidyl-threonine phosphorylation)|go:"GO:0019871"(sodium channel inhibitor activity)|go:"GO:0030007"(cellular potassium ion homeostasis)|go:"GO:0030315"(T-tubule)|go:"GO:0031432"(titin binding)|go:"GO:0031594"(neuromuscular junction)|go:"GO:0032469"(endoplasmic reticulum calcium ion homeostasis)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033017"(sarcoplasmic reticulum membrane)|go:"GO:0035022"(positive regulation of Rac protein signal transduction)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043005"(neuron projection)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043194"(axon initial segment)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0050998"(nitric-oxide synthase binding)|go:"GO:0055119"(relaxation of cardiac muscle)|go:"GO:0060048"(cardiac muscle contraction)|go:"GO:0060341"(regulation of cellular localization)|go:"GO:0061049"(cell growth involved in cardiac muscle cell development)|go:"GO:0070374"(positive regulation of ERK1 and ERK2 cascade)|go:"GO:0086003"(cardiac muscle cell contraction)|go:"GO:0098901"(regulation of cardiac muscle cell action potential)|go:"GO:0098909"(regulation of cardiac muscle cell action potential involved in regulation of contraction)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:1901844"(regulation of cell communication by electrical coupling involved in cardiac conduction)|go:"GO:1901897"(regulation of relaxation of cardiac muscle)|go:"GO:1902306"(negative regulation of sodium ion transmembrane transport)|go:"GO:1902514"(regulation of calcium ion transmembrane transport via high voltage-gated calcium channel)|go:"GO:1903076"(regulation of protein localization to plasma membrane)|go:"GO:1904707"(positive regulation of vascular associated smooth muscle cell proliferation)|refseq:XP_017446093.1|refseq:XP_017446094.1|refseq:XP_017446095.1|refseq:XP_017446099.1|refseq:XP_017446100.1|refseq:XP_017446102.1|refseq:XP_017446106.1|reactome:R-RNO-5576892|reactome:R-RNO-5578775|reactome:R-RNO-5673000|reactome:R-RNO-5673001|reactome:R-RNO-877300|reactome:R-RNO-936837|go:"GO:2000650"(negative regulation of sodium ion transmembrane transporter activity)|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR013543(Calcium/calmodulin dependent protein kinase II, association-domain)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR032710|mint:P15791|reactome:R-RNO-3371571|reactome:R-RNO-399719|reactome:R-RNO-438066	-	-	-	figure legend:ST1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10116(rat-brain-cerebellum)|taxid:10116(Rattus norvegicus)	-	2020/10/30	2020/10/30	rogid:DtE+ZXAZKdCMvUW5K+jXQ5bH07M10116	rogid:DrskswXp/QJHvHXeG0tWWxxV2K810116	rigid:OaXQ9NA25fwCWxejPU3Ao9q5j/E	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q5XIE8	uniprotkb:P23358	intact:EBI-15348306|ensembl:ENSRNOP00000023037	intact:EBI-916883|ensembl:ENSRNOP00000041462	psi-mi:itm2b_rat(display_long)|uniprotkb:Itm2b(gene name)|psi-mi:Itm2b(display_short)|uniprotkb:Immature BRI2(gene name synonym)|uniprotkb:Transmembrane protein BRI(gene name synonym)	psi-mi:rl12_rat(display_long)|uniprotkb:Rpl12(gene name)|psi-mi:Rpl12(display_short)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Martins et al. (2018)	imex:IM-28469|pubmed:29476059	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26438079|imex:IM-28469-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSRNOG00000016271(gene)|ensembl:ENSRNOT00000023037(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001540"(amyloid-beta binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0010008"(endosome membrane)|go:"GO:0030660"(Golgi-associated vesicle membrane)|go:"GO:0031301"(integral component of organelle membrane)|go:"GO:0042985"(negative regulation of amyloid precursor protein biosynthetic process)|interpro:IPR007084(BRICHOS)|interpro:IPR040145|mint:Q5XIE8|refseq:NP_001006964.1|rgd:620727	rgd:1565106|refseq:NP_001102668.1|refseq:XP_006227318.1|refseq:XP_006256697.1|ensembl:ENSRNOG00000028993(gene)|ensembl:ENSRNOT00000042736(transcript)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005634"(nucleus)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006412"(translation)|go:"GO:0014069"(postsynaptic density)|go:"GO:0015934"(large ribosomal subunit)|go:"GO:0022625"(cytosolic large ribosomal subunit)|go:"GO:0022626"(cytosolic ribosome)|go:"GO:0045901"(positive regulation of translational elongation)|go:"GO:0070180"(large ribosomal subunit rRNA binding)|interpro:IPR000911(Ribosomal protein L11)|interpro:IPR020783|interpro:IPR020784|interpro:IPR020785|interpro:IPR036769|interpro:IPR036796|mint:P23358|reactome:R-RNO-156827|reactome:R-RNO-1799339|reactome:R-RNO-6791226|reactome:R-RNO-72689|reactome:R-RNO-72706|reactome:R-RNO-975956|reactome:R-RNO-975957	-	-	-	figure legend:ST1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10116(rat-brain-cerebellum)|taxid:10116(Rattus norvegicus)	-	2020/10/30	2020/10/30	rogid:DtE+ZXAZKdCMvUW5K+jXQ5bH07M10116	rogid:HD3+OCF6/IffH5e5AZRD235vais10116	rigid:OaXQ9NA25fwCWxejPU3Ao9q5j/E	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q5XIE8	uniprotkb:Q9QUL6	intact:EBI-15348306|ensembl:ENSRNOP00000023037	intact:EBI-925794	psi-mi:itm2b_rat(display_long)|uniprotkb:Itm2b(gene name)|psi-mi:Itm2b(display_short)|uniprotkb:Immature BRI2(gene name synonym)|uniprotkb:Transmembrane protein BRI(gene name synonym)	psi-mi:nsf_rat(display_long)|uniprotkb:Nsf(gene name)|psi-mi:Nsf(display_short)|uniprotkb:Erg1(gene name synonym)|uniprotkb:N-ethylmaleimide-sensitive fusion protein(gene name synonym)|uniprotkb:Vesicular-fusion protein NSF(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Martins et al. (2018)	imex:IM-28469|pubmed:29476059	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26438079|imex:IM-28469-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSRNOG00000016271(gene)|ensembl:ENSRNOT00000023037(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001540"(amyloid-beta binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0010008"(endosome membrane)|go:"GO:0030660"(Golgi-associated vesicle membrane)|go:"GO:0031301"(integral component of organelle membrane)|go:"GO:0042985"(negative regulation of amyloid precursor protein biosynthetic process)|interpro:IPR007084(BRICHOS)|interpro:IPR040145|mint:Q5XIE8|refseq:NP_001006964.1|rgd:620727	rgd:621594|refseq:NP_068516.1|interpro:IPR009010(Aspartate decarboxylase-like fold)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR003959(AAA ATPase, core)|interpro:IPR003960(AAA ATPase, conserved site)|interpro:IPR003338(AAA ATPase VAT, N-terminal)|interpro:IPR004201(Cell division protein 48, CDC48, domain 2)|interpro:IPR027417|interpro:IPR029067|mint:Q9QUL6|interpro:IPR039812|interpro:IPR041569|go:"GO:0000149"(SNARE binding)|go:"GO:0001921"(positive regulation of receptor recycling)|go:"GO:0002090"(regulation of receptor internalization)|go:"GO:0005524"(ATP binding)|go:"GO:0005795"(Golgi stack)|go:"GO:0005886"(plasma membrane)|go:"GO:0006813"(potassium ion transport)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006891"(intra-Golgi vesicle-mediated transport)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0014069"(postsynaptic density)|go:"GO:0015031"(protein transport)|go:"GO:0016192"(vesicle-mediated transport)|go:"GO:0017075"(syntaxin-1 binding)|go:"GO:0017157"(regulation of exocytosis)|go:"GO:0019901"(protein kinase binding)|go:"GO:0019905"(syntaxin binding)|go:"GO:0030165"(PDZ domain binding)|go:"GO:0031267"(small GTPase binding)|go:"GO:0031748"(D1 dopamine receptor binding)|go:"GO:0032984"(protein-containing complex disassembly)|go:"GO:0035255"(ionotropic glutamate receptor binding)|go:"GO:0035494"(SNARE complex disassembly)|go:"GO:0043001"(Golgi to plasma membrane protein transport)|go:"GO:0043008"(ATP-dependent protein binding)|go:"GO:0043198"(dendritic shaft)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045732"(positive regulation of protein catabolic process)|go:"GO:0046872"(metal ion binding)|go:"GO:0048211"(Golgi vesicle docking)|go:"GO:0140545"(protein disaggregase activity)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|reactome:R-RNO-204005|reactome:R-RNO-416993|reactome:R-RNO-6807878|reactome:R-RNO-6811434|reactome:R-RNO-6811438|reactome:R-RNO-6811440	-	-	-	figure legend:ST1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10116(rat-brain-cerebellum)|taxid:10116(Rattus norvegicus)	-	2020/10/30	2020/10/30	rogid:DtE+ZXAZKdCMvUW5K+jXQ5bH07M10116	rogid:auiPGWRTO2wORmMBlQZuzHooO+M10116	rigid:OaXQ9NA25fwCWxejPU3Ao9q5j/E	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q5XIE8	uniprotkb:P69897	intact:EBI-15348306|ensembl:ENSRNOP00000023037	intact:EBI-350912|uniprotkb:P05218|uniprotkb:Q6P9X8|uniprotkb:Q9CY33|uniprotkb:Q8WUC1|ensembl:ENSRNOP00000075269	psi-mi:itm2b_rat(display_long)|uniprotkb:Itm2b(gene name)|psi-mi:Itm2b(display_short)|uniprotkb:Immature BRI2(gene name synonym)|uniprotkb:Transmembrane protein BRI(gene name synonym)	psi-mi:tbb5_rat(display_long)|uniprotkb:Tubb5(gene name)|psi-mi:Tubb5(display_short)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Martins et al. (2018)	imex:IM-28469|pubmed:29476059	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26438079|imex:IM-28469-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSRNOG00000016271(gene)|ensembl:ENSRNOT00000023037(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001540"(amyloid-beta binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0010008"(endosome membrane)|go:"GO:0030660"(Golgi-associated vesicle membrane)|go:"GO:0031301"(integral component of organelle membrane)|go:"GO:0042985"(negative regulation of amyloid precursor protein biosynthetic process)|interpro:IPR007084(BRICHOS)|interpro:IPR040145|mint:Q5XIE8|refseq:NP_001006964.1|rgd:620727	rgd:628596|refseq:NP_775125.1|go:"GO:0005634"(nucleus)|go:"GO:0005641"(nuclear envelope lumen)|go:"GO:0005737"(cytoplasm)|go:"GO:0005874"(microtubule)|go:"GO:0007017"(microtubule-based process)|go:"GO:0009987"(cellular process)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032794"(GTPase activating protein binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0036464"(cytoplasmic ribonucleoprotein granule)|go:"GO:0042288"(MHC class I protein binding)|go:"GO:0044297"(cell body)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045121"(membrane raft)|go:"GO:0050807"(regulation of synapse organization)|go:"GO:0051225"(spindle assembly)|interpro:IPR000217(Tubulin)|interpro:IPR002453(Beta tubulin)|go:"GO:0005525"(GTP binding)|interpro:IPR003008(Tubulin/FtsZ, GTPase)|interpro:IPR008280(Tubulin/FtsZ, C-terminal)|interpro:IPR013838(Beta tubulin, autoregulation binding site)|interpro:IPR017975|interpro:IPR018316|interpro:IPR023123|interpro:IPR036525|interpro:IPR037103|mint:P69897|reactome:R-RNO-2565942|reactome:R-RNO-380259|reactome:R-RNO-380270|reactome:R-RNO-380284|reactome:R-RNO-380320|reactome:R-RNO-5620912|reactome:R-RNO-6798695|reactome:R-RNO-8854518|ensembl:ENSRNOG00000061216(gene)|ensembl:ENSRNOT00000079854(transcript)|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0005200"(structural constituent of cytoskeleton)	-	-	-	figure legend:ST1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10116(rat-brain-cerebellum)|taxid:10116(Rattus norvegicus)	-	2020/10/30	2020/10/30	rogid:DtE+ZXAZKdCMvUW5K+jXQ5bH07M10116	rogid:B6pmb1dvCroZXGd/1Zazi+s72GA10116	rigid:OaXQ9NA25fwCWxejPU3Ao9q5j/E	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q5XIE8	uniprotkb:Q6P9T8	intact:EBI-15348306|ensembl:ENSRNOP00000023037	intact:EBI-919099	psi-mi:itm2b_rat(display_long)|uniprotkb:Itm2b(gene name)|psi-mi:Itm2b(display_short)|uniprotkb:Immature BRI2(gene name synonym)|uniprotkb:Transmembrane protein BRI(gene name synonym)	psi-mi:tbb4b_rat(display_long)|uniprotkb:Tubb4b(gene name)|psi-mi:Tubb4b(display_short)|uniprotkb:Tubb2c(gene name synonym)|uniprotkb:Tubulin beta-2C chain(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Martins et al. (2018)	imex:IM-28469|pubmed:29476059	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26438079|imex:IM-28469-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSRNOG00000016271(gene)|ensembl:ENSRNOT00000023037(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001540"(amyloid-beta binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0010008"(endosome membrane)|go:"GO:0030660"(Golgi-associated vesicle membrane)|go:"GO:0031301"(integral component of organelle membrane)|go:"GO:0042985"(negative regulation of amyloid precursor protein biosynthetic process)|interpro:IPR007084(BRICHOS)|interpro:IPR040145|mint:Q5XIE8|refseq:NP_001006964.1|rgd:620727	interpro:IPR008280(Tubulin/FtsZ, C-terminal)|interpro:IPR000217(Tubulin)|interpro:IPR018316|interpro:IPR017975|interpro:IPR003008(Tubulin/FtsZ, GTPase)|rgd:735101|refseq:NP_954525.1|interpro:IPR013838(Beta tubulin, autoregulation binding site)|interpro:IPR002453(Beta tubulin)|interpro:IPR023123|mint:Q6P9T8|interpro:IPR036525|interpro:IPR037103|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0003725"(double-stranded RNA binding)|go:"GO:0005200"(structural constituent of cytoskeleton)|go:"GO:0005525"(GTP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005874"(microtubule)|reactome:R-RNO-190840|reactome:R-RNO-2132295|reactome:R-RNO-2467813|reactome:R-RNO-2500257|reactome:R-RNO-2565942|reactome:R-RNO-3371497|reactome:R-RNO-380259|reactome:R-RNO-380270|reactome:R-RNO-380284|reactome:R-RNO-380320|reactome:R-RNO-437239|reactome:R-RNO-5610787|reactome:R-RNO-5617833|reactome:R-RNO-5620912|reactome:R-RNO-5620924|reactome:R-RNO-5626467|reactome:R-RNO-5663220|reactome:R-RNO-6798695|reactome:R-RNO-6807878|reactome:R-RNO-6811434|reactome:R-RNO-6811436|reactome:R-RNO-68877|reactome:R-RNO-8852276|reactome:R-RNO-8854518|reactome:R-RNO-8955332|reactome:R-RNO-9646399|reactome:R-RNO-9648025|reactome:R-RNO-9668328|reactome:R-RNO-983189	-	-	-	figure legend:ST1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10116(rat-brain-cerebellum)|taxid:10116(Rattus norvegicus)	-	2020/10/30	2020/10/30	rogid:DtE+ZXAZKdCMvUW5K+jXQ5bH07M10116	rogid:1RJgLTml+eflSvmnOyLoI1pFFTc10116	rigid:OaXQ9NA25fwCWxejPU3Ao9q5j/E	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q5XIE8	uniprotkb:Q4QRB4	intact:EBI-15348306|ensembl:ENSRNOP00000023037	intact:EBI-919537|uniprotkb:Q8K5B6|ensembl:ENSRNOP00000023452	psi-mi:itm2b_rat(display_long)|uniprotkb:Itm2b(gene name)|psi-mi:Itm2b(display_short)|uniprotkb:Immature BRI2(gene name synonym)|uniprotkb:Transmembrane protein BRI(gene name synonym)	psi-mi:tbb3_rat(display_long)|uniprotkb:Tubb3(gene name)|psi-mi:Tubb3(display_short)|uniprotkb:Neuron-specific class III beta-tubulin(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Martins et al. (2018)	imex:IM-28469|pubmed:29476059	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26438079|imex:IM-28469-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSRNOG00000016271(gene)|ensembl:ENSRNOT00000023037(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001540"(amyloid-beta binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0010008"(endosome membrane)|go:"GO:0030660"(Golgi-associated vesicle membrane)|go:"GO:0031301"(integral component of organelle membrane)|go:"GO:0042985"(negative regulation of amyloid precursor protein biosynthetic process)|interpro:IPR007084(BRICHOS)|interpro:IPR040145|mint:Q5XIE8|refseq:NP_001006964.1|rgd:620727	rgd:628595|refseq:NP_640347.2|ensembl:ENSRNOG00000017209(gene)|ensembl:ENSRNOT00000023452(transcript)|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0005200"(structural constituent of cytoskeleton)|go:"GO:0005525"(GTP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005874"(microtubule)|go:"GO:0007411"(axon guidance)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0030027"(lamellipodium)|go:"GO:0030175"(filopodium)|go:"GO:0030182"(neuron differentiation)|go:"GO:0030424"(axon)|go:"GO:0030425"(dendrite)|go:"GO:0030426"(growth cone)|go:"GO:0038007"(netrin-activated signaling pathway)|go:"GO:0042277"(peptide binding)|go:"GO:0043025"(neuronal cell body)|go:"GO:0071944"(cell periphery)|go:"GO:1990791"(dorsal root ganglion development)|go:"GO:1990890"(netrin receptor binding)|interpro:IPR000217(Tubulin)|interpro:IPR002453(Beta tubulin)|interpro:IPR003008(Tubulin/FtsZ, GTPase)|interpro:IPR008280(Tubulin/FtsZ, C-terminal)|interpro:IPR013838(Beta tubulin, autoregulation binding site)|interpro:IPR017975|interpro:IPR018316|interpro:IPR023123|interpro:IPR036525|interpro:IPR037103|mint:Q4QRB4|reactome:R-RNO-190840|reactome:R-RNO-2132295|reactome:R-RNO-2467813|reactome:R-RNO-2500257|reactome:R-RNO-3371497|reactome:R-RNO-380320|reactome:R-RNO-437239|reactome:R-RNO-5610787|reactome:R-RNO-5617833|reactome:R-RNO-5620924|reactome:R-RNO-5626467|reactome:R-RNO-5663220|reactome:R-RNO-6807878|reactome:R-RNO-6811434|reactome:R-RNO-6811436|reactome:R-RNO-68877|reactome:R-RNO-8852276|reactome:R-RNO-8955332|reactome:R-RNO-9646399|reactome:R-RNO-9648025|reactome:R-RNO-9668328|reactome:R-RNO-983189	-	-	-	figure legend:ST1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10116(rat-brain-cerebellum)|taxid:10116(Rattus norvegicus)	-	2020/10/30	2020/10/30	rogid:DtE+ZXAZKdCMvUW5K+jXQ5bH07M10116	rogid:KhUQ3YFdcJvjwoHGykl7dv90vX810116	rigid:OaXQ9NA25fwCWxejPU3Ao9q5j/E	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q5XIE8	uniprotkb:P85108	intact:EBI-15348306|ensembl:ENSRNOP00000023037	intact:EBI-2696554|ensembl:ENSRNOP00000023611|ensembl:ENSRNOP00000071729	psi-mi:itm2b_rat(display_long)|uniprotkb:Itm2b(gene name)|psi-mi:Itm2b(display_short)|uniprotkb:Immature BRI2(gene name synonym)|uniprotkb:Transmembrane protein BRI(gene name synonym)	psi-mi:tbb2a_rat(display_long)|uniprotkb:Tubb2a(gene name)|psi-mi:Tubb2a(display_short)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Martins et al. (2018)	imex:IM-28469|pubmed:29476059	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26438079|imex:IM-28469-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSRNOG00000016271(gene)|ensembl:ENSRNOT00000023037(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001540"(amyloid-beta binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0010008"(endosome membrane)|go:"GO:0030660"(Golgi-associated vesicle membrane)|go:"GO:0031301"(integral component of organelle membrane)|go:"GO:0042985"(negative regulation of amyloid precursor protein biosynthetic process)|interpro:IPR007084(BRICHOS)|interpro:IPR040145|mint:Q5XIE8|refseq:NP_001006964.1|rgd:620727	rgd:1588452|refseq:NP_001102589.1|ensembl:ENSRNOG00000017558(gene)|ensembl:ENSRNOT00000023611(transcript)|ensembl:ENSRNOT00000086264(transcript)|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0001764"(neuron migration)|go:"GO:0005200"(structural constituent of cytoskeleton)|go:"GO:0005525"(GTP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005874"(microtubule)|interpro:IPR000217(Tubulin)|interpro:IPR002453(Beta tubulin)|interpro:IPR003008(Tubulin/FtsZ, GTPase)|interpro:IPR008280(Tubulin/FtsZ, C-terminal)|interpro:IPR013838(Beta tubulin, autoregulation binding site)|interpro:IPR017975|interpro:IPR018316|interpro:IPR023123|interpro:IPR036525|interpro:IPR037103|mint:P85108|reactome:R-RNO-190840|reactome:R-RNO-2132295|reactome:R-RNO-2467813|reactome:R-RNO-2500257|reactome:R-RNO-3371497|reactome:R-RNO-380320|reactome:R-RNO-437239|reactome:R-RNO-5610787|reactome:R-RNO-5617833|reactome:R-RNO-5620924|reactome:R-RNO-5626467|reactome:R-RNO-5663220|reactome:R-RNO-6807878|reactome:R-RNO-6811434|reactome:R-RNO-6811436|reactome:R-RNO-68877|reactome:R-RNO-8852276|reactome:R-RNO-8955332|reactome:R-RNO-9646399|reactome:R-RNO-9648025|reactome:R-RNO-9668328|reactome:R-RNO-983189	-	-	-	figure legend:ST1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10116(rat-brain-cerebellum)|taxid:10116(Rattus norvegicus)	-	2020/10/30	2020/10/30	rogid:DtE+ZXAZKdCMvUW5K+jXQ5bH07M10116	rogid:XN9uTGU0KxQjMod0AGnM+XJoHyk10116	rigid:OaXQ9NA25fwCWxejPU3Ao9q5j/E	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q5XIE8	uniprotkb:Q5XIF6	intact:EBI-15348306|ensembl:ENSRNOP00000023037	intact:EBI-2255850|ensembl:ENSRNOP00000004797	psi-mi:itm2b_rat(display_long)|uniprotkb:Itm2b(gene name)|psi-mi:Itm2b(display_short)|uniprotkb:Immature BRI2(gene name synonym)|uniprotkb:Transmembrane protein BRI(gene name synonym)	psi-mi:tba4a_rat(display_long)|uniprotkb:Tuba4a(gene name)|psi-mi:Tuba4a(display_short)|uniprotkb:Tuba4(gene name synonym)|uniprotkb:Tubulin alpha-4 chain(gene name synonym)|uniprotkb:Alpha-tubulin 4(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Martins et al. (2018)	imex:IM-28469|pubmed:29476059	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26438079|imex:IM-28469-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSRNOG00000016271(gene)|ensembl:ENSRNOT00000023037(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001540"(amyloid-beta binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0010008"(endosome membrane)|go:"GO:0030660"(Golgi-associated vesicle membrane)|go:"GO:0031301"(integral component of organelle membrane)|go:"GO:0042985"(negative regulation of amyloid precursor protein biosynthetic process)|interpro:IPR007084(BRICHOS)|interpro:IPR040145|mint:Q5XIE8|refseq:NP_001006964.1|rgd:620727	rgd:1359623|refseq:NP_001007005.1|ensembl:ENSRNOG00000003597(gene)|ensembl:ENSRNOT00000004797(transcript)|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0005200"(structural constituent of cytoskeleton)|go:"GO:0005525"(GTP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005874"(microtubule)|go:"GO:0019899"(enzyme binding)|go:"GO:0019901"(protein kinase binding)|interpro:IPR000217(Tubulin)|interpro:IPR002452(Alpha tubulin)|interpro:IPR003008(Tubulin/FtsZ, GTPase)|interpro:IPR008280(Tubulin/FtsZ, C-terminal)|interpro:IPR017975|interpro:IPR018316|interpro:IPR023123|interpro:IPR036525|interpro:IPR037103|mint:Q5XIF6|reactome:R-RNO-114608|reactome:R-RNO-190840|reactome:R-RNO-2132295|reactome:R-RNO-2467813|reactome:R-RNO-2500257|reactome:R-RNO-2565942|reactome:R-RNO-3371497|reactome:R-RNO-380259|reactome:R-RNO-380270|reactome:R-RNO-380284|reactome:R-RNO-380320|reactome:R-RNO-437239|reactome:R-RNO-5610787|reactome:R-RNO-5617833|reactome:R-RNO-5620912|reactome:R-RNO-5620924|reactome:R-RNO-5626467|reactome:R-RNO-5663220|reactome:R-RNO-6807878|reactome:R-RNO-6811434|reactome:R-RNO-6811436|reactome:R-RNO-68877|reactome:R-RNO-8852276|reactome:R-RNO-8854518|reactome:R-RNO-8955332|reactome:R-RNO-9646399|reactome:R-RNO-9648025|reactome:R-RNO-9668328|reactome:R-RNO-983189	-	-	-	figure legend:ST1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10116(rat-brain-cerebellum)|taxid:10116(Rattus norvegicus)	-	2020/10/30	2020/10/30	rogid:DtE+ZXAZKdCMvUW5K+jXQ5bH07M10116	rogid:6Oj9O8u7E6cLUJ1eT6y5slbk7uQ10116	rigid:OaXQ9NA25fwCWxejPU3Ao9q5j/E	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q5XIE8	uniprotkb:P68370	intact:EBI-15348306|ensembl:ENSRNOP00000023037	intact:EBI-349571|uniprotkb:P02551|uniprotkb:P05210|uniprotkb:P05212|uniprotkb:Q6P6G6|ensembl:ENSRNOP00000075232	psi-mi:itm2b_rat(display_long)|uniprotkb:Itm2b(gene name)|psi-mi:Itm2b(display_short)|uniprotkb:Immature BRI2(gene name synonym)|uniprotkb:Transmembrane protein BRI(gene name synonym)	psi-mi:tba1a_rat(display_long)|uniprotkb:Tuba1a(gene name)|psi-mi:Tuba1a(display_short)|uniprotkb:Tuba1(gene name synonym)|uniprotkb:Tubulin alpha-1 chain(gene name synonym)|uniprotkb:Alpha-tubulin 1(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Martins et al. (2018)	imex:IM-28469|pubmed:29476059	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26438079|imex:IM-28469-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSRNOG00000016271(gene)|ensembl:ENSRNOT00000023037(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001540"(amyloid-beta binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0010008"(endosome membrane)|go:"GO:0030660"(Golgi-associated vesicle membrane)|go:"GO:0031301"(integral component of organelle membrane)|go:"GO:0042985"(negative regulation of amyloid precursor protein biosynthetic process)|interpro:IPR007084(BRICHOS)|interpro:IPR040145|mint:Q5XIE8|refseq:NP_001006964.1|rgd:620727	rgd:619717|refseq:NP_071634.1|go:"GO:0005200"(structural constituent of cytoskeleton)|go:"GO:0005525"(GTP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005874"(microtubule)|go:"GO:0005881"(cytoplasmic microtubule)|go:"GO:0007017"(microtubule-based process)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0031594"(neuromuscular junction)|go:"GO:0036464"(cytoplasmic ribonucleoprotein granule)|go:"GO:0042802"(identical protein binding)|go:"GO:0043209"(myelin sheath)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045121"(membrane raft)|go:"GO:0050807"(regulation of synapse organization)|go:"GO:0055037"(recycling endosome)|interpro:IPR000217(Tubulin)|interpro:IPR002452(Alpha tubulin)|interpro:IPR003008(Tubulin/FtsZ, GTPase)|interpro:IPR008280(Tubulin/FtsZ, C-terminal)|interpro:IPR017975|interpro:IPR018316|ensembl:ENSRNOG00000060728(gene)|ensembl:ENSRNOT00000083156(transcript)|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0000278"(mitotic cell cycle)|interpro:IPR023123|interpro:IPR036525|interpro:IPR037103|mint:P68370|reactome:R-RNO-190840|reactome:R-RNO-2132295|reactome:R-RNO-2467813|reactome:R-RNO-2500257|reactome:R-RNO-2565942|reactome:R-RNO-3371497|reactome:R-RNO-380259|reactome:R-RNO-380270|reactome:R-RNO-380284|reactome:R-RNO-380320|reactome:R-RNO-437239|reactome:R-RNO-5610787|reactome:R-RNO-5617833|reactome:R-RNO-5620912|reactome:R-RNO-5620924|reactome:R-RNO-5626467|reactome:R-RNO-5663220|reactome:R-RNO-6807878|reactome:R-RNO-6811434|reactome:R-RNO-6811436|reactome:R-RNO-68877|reactome:R-RNO-8852276|reactome:R-RNO-8854518|reactome:R-RNO-8955332|reactome:R-RNO-9646399|reactome:R-RNO-9648025|reactome:R-RNO-9668328|reactome:R-RNO-983189	-	-	-	figure legend:ST1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10116(rat-brain-cerebellum)|taxid:10116(Rattus norvegicus)	-	2020/10/30	2020/10/30	rogid:DtE+ZXAZKdCMvUW5K+jXQ5bH07M10116	rogid:1CzEzrf5y8hrQRPKgWQS1Wm1aCY10116	rigid:OaXQ9NA25fwCWxejPU3Ao9q5j/E	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q5XIE8	uniprotkb:Q68A21	intact:EBI-15348306|ensembl:ENSRNOP00000023037	intact:EBI-26437870	psi-mi:itm2b_rat(display_long)|uniprotkb:Itm2b(gene name)|psi-mi:Itm2b(display_short)|uniprotkb:Immature BRI2(gene name synonym)|uniprotkb:Transmembrane protein BRI(gene name synonym)	psi-mi:purb_rat(display_long)|uniprotkb:Purb(gene name)|psi-mi:Purb(display_short)|uniprotkb:Purine-rich element-binding protein B(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Martins et al. (2018)	imex:IM-28469|pubmed:29476059	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26438079|imex:IM-28469-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSRNOG00000016271(gene)|ensembl:ENSRNOT00000023037(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001540"(amyloid-beta binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0010008"(endosome membrane)|go:"GO:0030660"(Golgi-associated vesicle membrane)|go:"GO:0031301"(integral component of organelle membrane)|go:"GO:0042985"(negative regulation of amyloid precursor protein biosynthetic process)|interpro:IPR007084(BRICHOS)|interpro:IPR040145|mint:Q5XIE8|refseq:NP_001006964.1|rgd:620727	go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0046332"(SMAD binding)|go:"GO:0140297"(DNA-binding transcription factor binding)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000900"(translation repressor activity, mRNA regulatory element binding)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0008283"(cell population proliferation)|go:"GO:0030154"(cell differentiation)|go:"GO:0032422"(purine-rich negative regulatory element binding)|mint:Q68A21|refseq:NP_001017503.1|interpro:IPR006628(PUR-alpha/beta/gamma, DNA/RNA-binding)|interpro:IPR030499|rgd:1559465	-	-	-	figure legend:ST1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10116(rat-brain-cerebellum)|taxid:10116(Rattus norvegicus)	-	2020/10/30	2020/10/30	rogid:DtE+ZXAZKdCMvUW5K+jXQ5bH07M10116	rogid:C/1C29JkX6J5Sb4qhdTIrNfNsAQ10116	rigid:OaXQ9NA25fwCWxejPU3Ao9q5j/E	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q5XIE8	uniprotkb:Q05546	intact:EBI-15348306|ensembl:ENSRNOP00000023037	intact:EBI-1039732	psi-mi:itm2b_rat(display_long)|uniprotkb:Itm2b(gene name)|psi-mi:Itm2b(display_short)|uniprotkb:Immature BRI2(gene name synonym)|uniprotkb:Transmembrane protein BRI(gene name synonym)	psi-mi:tenr_rat(display_long)|uniprotkb:Tnr(gene name)|psi-mi:Tnr(display_short)|uniprotkb:Restrictin(gene name synonym)|uniprotkb:Janusin(gene name synonym)|uniprotkb:Neural recognition molecule J1-160/180(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Martins et al. (2018)	imex:IM-28469|pubmed:29476059	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26438079|imex:IM-28469-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSRNOG00000016271(gene)|ensembl:ENSRNOT00000023037(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001540"(amyloid-beta binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0010008"(endosome membrane)|go:"GO:0030660"(Golgi-associated vesicle membrane)|go:"GO:0031301"(integral component of organelle membrane)|go:"GO:0042985"(negative regulation of amyloid precursor protein biosynthetic process)|interpro:IPR007084(BRICHOS)|interpro:IPR040145|mint:Q5XIE8|refseq:NP_001006964.1|rgd:620727	rgd:3886|refseq:NP_037177.1|interpro:IPR002181(Fibrinogen, alpha/beta/gamma chain, C-terminal globular)|interpro:IPR003961(Fibronectin, type III)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR033079|interpro:IPR014716(Fibrinogen, alpha/beta/gamma chain, C-terminal globular, subdomain 1)|mint:Q05546|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005178"(integrin binding)|go:"GO:0005615"(extracellular space)|go:"GO:0007155"(cell adhesion)|go:"GO:0007158"(neuron cell-cell adhesion)|go:"GO:0007162"(negative regulation of cell adhesion)|go:"GO:0007399"(nervous system development)|go:"GO:0008306"(associative learning)|go:"GO:0009986"(cell surface)|go:"GO:0010977"(negative regulation of neuron projection development)|go:"GO:0022029"(telencephalon cell migration)|go:"GO:0022408"(negative regulation of cell-cell adhesion)|go:"GO:0030198"(extracellular matrix organization)|go:"GO:0030517"(negative regulation of axon extension)|go:"GO:0031012"(extracellular matrix)|go:"GO:0035641"(locomotory exploration behavior)|go:"GO:0045121"(membrane raft)|go:"GO:0048692"(negative regulation of axon extension involved in regeneration)|go:"GO:0050804"(modulation of chemical synaptic transmission)|go:"GO:0050805"(negative regulation of synaptic transmission)|go:"GO:0050808"(synapse organization)|go:"GO:0050885"(neuromuscular process controlling balance)|go:"GO:0051968"(positive regulation of synaptic transmission, glutamatergic)|go:"GO:0051971"(positive regulation of transmission of nerve impulse)|go:"GO:0060291"(long-term synaptic potentiation)|go:"GO:0062023"(collagen-containing extracellular matrix)|go:"GO:0072534"(perineuronal net)|go:"GO:0098685"(Schaffer collateral - CA1 synapse)|go:"GO:0098686"(hippocampal mossy fiber to CA3 synapse)|go:"GO:0098966"(perisynaptic extracellular matrix)|go:"GO:0098978"(glutamatergic synapse)|rcsb pdb:1TDQ|reactome:R-RNO-3000178|interpro:IPR000742(EGF-like, type 3)|interpro:IPR036056|interpro:IPR036116|interpro:IPR041161	-	-	-	figure legend:ST1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10116(rat-brain-cerebellum)|taxid:10116(Rattus norvegicus)	-	2020/10/30	2020/10/30	rogid:DtE+ZXAZKdCMvUW5K+jXQ5bH07M10116	rogid:Z810KbeOItf8zwgtic+nWX8azEM10116	rigid:OaXQ9NA25fwCWxejPU3Ao9q5j/E	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q5XIE8	uniprotkb:Q68FQ0	intact:EBI-15348306|ensembl:ENSRNOP00000023037	intact:EBI-931470|uniprotkb:Q6PCT4|ensembl:ENSRNOP00000015886	psi-mi:itm2b_rat(display_long)|uniprotkb:Itm2b(gene name)|psi-mi:Itm2b(display_short)|uniprotkb:Immature BRI2(gene name synonym)|uniprotkb:Transmembrane protein BRI(gene name synonym)	psi-mi:tcpe_rat(display_long)|uniprotkb:Cct5(gene name)|psi-mi:Cct5(display_short)|uniprotkb:CCT-epsilon(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Martins et al. (2018)	imex:IM-28469|pubmed:29476059	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26438079|imex:IM-28469-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSRNOG00000016271(gene)|ensembl:ENSRNOT00000023037(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001540"(amyloid-beta binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0010008"(endosome membrane)|go:"GO:0030660"(Golgi-associated vesicle membrane)|go:"GO:0031301"(integral component of organelle membrane)|go:"GO:0042985"(negative regulation of amyloid precursor protein biosynthetic process)|interpro:IPR007084(BRICHOS)|interpro:IPR040145|mint:Q5XIE8|refseq:NP_001006964.1|rgd:620727	rgd:735161|refseq:NP_001004078.1|ensembl:ENSRNOG00000011632(gene)|ensembl:ENSRNOT00000015886(transcript)|go:"GO:0003730"(mRNA 3'-UTR binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005813"(centrosome)|go:"GO:0005832"(chaperonin-containing T-complex)|go:"GO:0005874"(microtubule)|go:"GO:0006457"(protein folding)|go:"GO:0007339"(binding of sperm to zona pellucida)|go:"GO:0009615"(response to virus)|go:"GO:0031681"(G-protein beta-subunit binding)|go:"GO:0032212"(positive regulation of telomere maintenance via telomerase)|go:"GO:0044183"(protein folding chaperone)|go:"GO:0044297"(cell body)|go:"GO:0048027"(mRNA 5'-UTR binding)|go:"GO:0048487"(beta-tubulin binding)|go:"GO:0050821"(protein stabilization)|go:"GO:0051082"(unfolded protein binding)|go:"GO:1901998"(toxin transport)|go:"GO:1904851"(positive regulation of establishment of protein localization to telomere)|interpro:IPR002194(Chaperonin TCP-1, conserved site)|interpro:IPR002423(Chaperonin Cpn60/TCP-1)|interpro:IPR012718(T-complex protein 1, epsilon subunit)|interpro:IPR017998|interpro:IPR027409|interpro:IPR027410|interpro:IPR027413|mint:Q68FQ0|reactome:R-RNO-390471|reactome:R-RNO-5620922|reactome:R-RNO-6814122	-	-	-	figure legend:ST1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10116(rat-brain-cerebellum)|taxid:10116(Rattus norvegicus)	-	2020/10/30	2020/10/30	rogid:DtE+ZXAZKdCMvUW5K+jXQ5bH07M10116	rogid:ABW24Esuv9oCZYZr+++2wlVSTcI10116	rigid:OaXQ9NA25fwCWxejPU3Ao9q5j/E	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q5XIE8	uniprotkb:P61265	intact:EBI-15348306|ensembl:ENSRNOP00000023037	intact:EBI-2255905|uniprotkb:P32853|ensembl:ENSRNOP00000026063	psi-mi:itm2b_rat(display_long)|uniprotkb:Itm2b(gene name)|psi-mi:Itm2b(display_short)|uniprotkb:Immature BRI2(gene name synonym)|uniprotkb:Transmembrane protein BRI(gene name synonym)	psi-mi:stx1b_rat(display_long)|uniprotkb:Stx1b(gene name)|psi-mi:Stx1b(display_short)|uniprotkb:Stx1b2(gene name synonym)|uniprotkb:Syntaxin-1B2(gene name synonym)|uniprotkb:P35B(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Martins et al. (2018)	imex:IM-28469|pubmed:29476059	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26438079|imex:IM-28469-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSRNOG00000016271(gene)|ensembl:ENSRNOT00000023037(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001540"(amyloid-beta binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0010008"(endosome membrane)|go:"GO:0030660"(Golgi-associated vesicle membrane)|go:"GO:0031301"(integral component of organelle membrane)|go:"GO:0042985"(negative regulation of amyloid precursor protein biosynthetic process)|interpro:IPR007084(BRICHOS)|interpro:IPR040145|mint:Q5XIE8|refseq:NP_001006964.1|rgd:620727	rgd:3784|refseq:NP_036832.1|go:"GO:0016079"(synaptic vesicle exocytosis)|go:"GO:0016081"(synaptic vesicle docking)|go:"GO:0016192"(vesicle-mediated transport)|go:"GO:0017157"(regulation of exocytosis)|go:"GO:0019901"(protein kinase binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030424"(axon)|go:"GO:0031201"(SNARE complex)|go:"GO:0031594"(neuromuscular junction)|go:"GO:0031629"(synaptic vesicle fusion to presynaptic active zone membrane)|go:"GO:0042734"(presynaptic membrane)|go:"GO:0048278"(vesicle docking)|go:"GO:0048787"(presynaptic active zone membrane)|go:"GO:0048791"(calcium ion-regulated exocytosis of neurotransmitter)|go:"GO:0060025"(regulation of synaptic activity)|go:"GO:0061669"(spontaneous neurotransmitter secretion)|go:"GO:0072657"(protein localization to membrane)|go:"GO:0098793"(presynapse)|go:"GO:0098967"(exocytic insertion of neurotransmitter receptor to postsynaptic membrane)|go:"GO:1903422"(negative regulation of synaptic vesicle recycling)|go:"GO:1904050"(positive regulation of spontaneous neurotransmitter secretion)|go:"GO:1905302"(negative regulation of macropinocytosis)|go:"GO:2000463"(positive regulation of excitatory postsynaptic potential)|interpro:IPR000727(Target SNARE coiled-coil region)|interpro:IPR006011(Syntaxin, N-terminal)|interpro:IPR006012(Syntaxin/epimorphin, conserved site)|interpro:IPR010989(t-SNARE)|interpro:IPR028669|mint:P61265|reactome:R-RNO-5682910|ensembl:ENSRNOG00000019193(gene)|ensembl:ENSRNOT00000026063(transcript)|go:"GO:0000149"(SNARE binding)|go:"GO:0001956"(positive regulation of neurotransmitter secretion)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005484"(SNAP receptor activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006887"(exocytosis)|go:"GO:0006904"(vesicle docking involved in exocytosis)|go:"GO:0006906"(vesicle fusion)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0010807"(regulation of synaptic vesicle priming)|go:"GO:0010977"(negative regulation of neuron projection development)|go:"GO:0012505"(endomembrane system)|go:"GO:0015031"(protein transport)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)	-	-	-	figure legend:ST1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10116(rat-brain-cerebellum)|taxid:10116(Rattus norvegicus)	-	2020/10/30	2020/10/30	rogid:DtE+ZXAZKdCMvUW5K+jXQ5bH07M10116	rogid:B3aWVxxX3lZ8hOYK4gxwZupY7g410116	rigid:OaXQ9NA25fwCWxejPU3Ao9q5j/E	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q5XIE8	uniprotkb:P21707	intact:EBI-15348306|ensembl:ENSRNOP00000023037	intact:EBI-458098|uniprotkb:Q3S2E6|uniprotkb:Q707P5|ensembl:ENSRNOP00000049624|ensembl:ENSRNOP00000069194	psi-mi:itm2b_rat(display_long)|uniprotkb:Itm2b(gene name)|psi-mi:Itm2b(display_short)|uniprotkb:Immature BRI2(gene name synonym)|uniprotkb:Transmembrane protein BRI(gene name synonym)	psi-mi:syt1_rat(display_long)|uniprotkb:Syt1(gene name)|psi-mi:Syt1(display_short)|uniprotkb:Synaptotagmin I(gene name synonym)|uniprotkb:p65(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Martins et al. (2018)	imex:IM-28469|pubmed:29476059	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26438079|imex:IM-28469-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSRNOG00000016271(gene)|ensembl:ENSRNOT00000023037(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001540"(amyloid-beta binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0010008"(endosome membrane)|go:"GO:0030660"(Golgi-associated vesicle membrane)|go:"GO:0031301"(integral component of organelle membrane)|go:"GO:0042985"(negative regulation of amyloid precursor protein biosynthetic process)|interpro:IPR007084(BRICHOS)|interpro:IPR040145|mint:Q5XIE8|refseq:NP_001006964.1|rgd:620727	rgd:3803|refseq:NP_001028852.2|ensembl:ENSRNOG00000006426(gene)|ensembl:ENSRNOT00000048880(transcript)|ensembl:ENSRNOT00000088950(transcript)|go:"GO:0000149"(SNARE binding)|go:"GO:0001786"(phosphatidylserine binding)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005513"(detection of calcium ion)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005543"(phospholipid binding)|go:"GO:0005544"(calcium-dependent phospholipid binding)|go:"GO:0005546"(phosphatidylinositol-4,5-bisphosphate binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0007269"(neurotransmitter secretion)|go:"GO:0007420"(brain development)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0014059"(regulation of dopamine secretion)|go:"GO:0016079"(synaptic vesicle exocytosis)|go:"GO:0016192"(vesicle-mediated transport)|go:"GO:0017075"(syntaxin-1 binding)|go:"GO:0017156"(calcium-ion regulated exocytosis)|go:"GO:0017158"(regulation of calcium ion-dependent exocytosis)|go:"GO:0019905"(syntaxin binding)|go:"GO:0030141"(secretory granule)|go:"GO:0030154"(cell differentiation)|go:"GO:0030276"(clathrin binding)|go:"GO:0030285"(integral component of synaptic vesicle membrane)|go:"GO:0030348"(syntaxin-3 binding)|go:"GO:0030424"(axon)|go:"GO:0030672"(synaptic vesicle membrane)|go:"GO:0031045"(dense core granule)|go:"GO:0031340"(positive regulation of vesicle fusion)|go:"GO:0033603"(positive regulation of dopamine secretion)|go:"GO:0042584"(chromaffin granule membrane)|go:"GO:0042734"(presynaptic membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0043005"(neuron projection)|go:"GO:0043195"(terminal bouton)|go:"GO:0043229"(intracellular organelle)|go:"GO:0044306"(neuron projection terminus)|go:"GO:0045956"(positive regulation of calcium ion-dependent exocytosis)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0048278"(vesicle docking)|go:"GO:0048306"(calcium-dependent protein binding)|go:"GO:0048488"(synaptic vesicle endocytosis)|go:"GO:0048791"(calcium ion-regulated exocytosis of neurotransmitter)|go:"GO:0050750"(low-density lipoprotein particle receptor binding)|go:"GO:0050806"(positive regulation of synaptic transmission)|go:"GO:0051291"(protein heterooligomerization)|go:"GO:0051592"(response to calcium ion)|go:"GO:0051966"(regulation of synaptic transmission, glutamatergic)|go:"GO:0060076"(excitatory synapse)|go:"GO:0061669"(spontaneous neurotransmitter secretion)|go:"GO:0061891"(calcium ion sensor activity)|go:"GO:0070382"(exocytic vesicle)|go:"GO:0071277"(cellular response to calcium ion)|go:"GO:0071911"(synchronous neurotransmitter secretion)|go:"GO:0098686"(hippocampal mossy fiber to CA3 synapse)|go:"GO:0098746"(fast, calcium ion-dependent exocytosis of neurotransmitter)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099502"(calcium-dependent activation of synaptic vesicle fusion)|go:"GO:1903235"(positive regulation of calcium ion-dependent exocytosis of neurotransmitter)|go:"GO:1903305"(regulation of regulated secretory pathway)|go:"GO:1903861"(positive regulation of dendrite extension)|go:"GO:2000300"(regulation of synaptic vesicle exocytosis)|interpro:IPR000008(C2 calcium-dependent membrane targeting)|interpro:IPR001565(Synaptotagmin)|interpro:IPR015428(Synaptotagmin 1,2)|interpro:IPR035892|mint:P21707|rcsb pdb:1BYN|rcsb pdb:1K5W|rcsb pdb:1RSY|rcsb pdb:1TJM|rcsb pdb:1TJX|rcsb pdb:1UOV|rcsb pdb:1UOW|rcsb pdb:2YOA|rcsb pdb:4WEE|rcsb pdb:5CCG|rcsb pdb:5CCH|rcsb pdb:5CCI|rcsb pdb:5CCJ|rcsb pdb:5KJ7|rcsb pdb:5KJ8|rcsb pdb:5W5C|rcsb pdb:5W5D|rcsb pdb:6CXW|rcsb pdb:6MTI|reactome:R-RNO-181429|reactome:R-RNO-181430|reactome:R-RNO-210500|reactome:R-RNO-212676|reactome:R-RNO-264642|reactome:R-RNO-8856825|reactome:R-RNO-8856828|reactome:R-RNO-888590|refseq:XP_017450168.1|dip:DIP-29064N	-	-	-	figure legend:ST1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10116(rat-brain-cerebellum)|taxid:10116(Rattus norvegicus)	-	2020/10/30	2020/10/30	rogid:DtE+ZXAZKdCMvUW5K+jXQ5bH07M10116	rogid:fr7zfj22zAOY/bJ7psjrgnsb0g810116	rigid:OaXQ9NA25fwCWxejPU3Ao9q5j/E	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q5XIE8	uniprotkb:Q02563	intact:EBI-15348306|ensembl:ENSRNOP00000023037	intact:EBI-466194|uniprotkb:Q58DZ8|ensembl:ENSRNOP00000028760	psi-mi:itm2b_rat(display_long)|uniprotkb:Itm2b(gene name)|psi-mi:Itm2b(display_short)|uniprotkb:Immature BRI2(gene name synonym)|uniprotkb:Transmembrane protein BRI(gene name synonym)	psi-mi:sv2a_rat(display_long)|uniprotkb:Sv2a(gene name)|psi-mi:Sv2a(display_short)|uniprotkb:Sv2(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Martins et al. (2018)	imex:IM-28469|pubmed:29476059	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26438079|imex:IM-28469-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSRNOG00000016271(gene)|ensembl:ENSRNOT00000023037(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001540"(amyloid-beta binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0010008"(endosome membrane)|go:"GO:0030660"(Golgi-associated vesicle membrane)|go:"GO:0031301"(integral component of organelle membrane)|go:"GO:0042985"(negative regulation of amyloid precursor protein biosynthetic process)|interpro:IPR007084(BRICHOS)|interpro:IPR040145|mint:Q5XIE8|refseq:NP_001006964.1|rgd:620727	rgd:619715|refseq:NP_476558.2|refseq:XP_006233014.1|ensembl:ENSRNOT00000028760(transcript)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005911"(cell-cell junction)|go:"GO:0006836"(neurotransmitter transport)|go:"GO:0006874"(cellular calcium ion homeostasis)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0014052"(regulation of gamma-aminobutyric acid secretion)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016082"(synaptic vesicle priming)|go:"GO:0019901"(protein kinase binding)|go:"GO:0022857"(transmembrane transporter activity)|go:"GO:0030285"(integral component of synaptic vesicle membrane)|go:"GO:0030425"(dendrite)|go:"GO:0030672"(synaptic vesicle membrane)|go:"GO:0031594"(neuromuscular junction)|go:"GO:0043005"(neuron projection)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043195"(terminal bouton)|go:"GO:0045202"(synapse)|go:"GO:0048786"(presynaptic active zone)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0098982"(GABA-ergic synapse)|interpro:IPR001646(Pentapeptide repeat)|interpro:IPR005828(General substrate transporter)|interpro:IPR005829(Sugar transporter, conserved site)|interpro:IPR011701(Major facilitator superfamily MFS-1)|interpro:IPR020846|interpro:IPR022308|interpro:IPR036259|mint:Q02563|ensembl:ENSRNOG00000021182(gene)	-	-	-	figure legend:ST1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10116(rat-brain-cerebellum)|taxid:10116(Rattus norvegicus)	-	2020/10/30	2020/10/30	rogid:DtE+ZXAZKdCMvUW5K+jXQ5bH07M10116	rogid:a7TA6gTNT5eWAIVLxjT1dgUQzn410116	rigid:OaXQ9NA25fwCWxejPU3Ao9q5j/E	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q5XIE8	uniprotkb:P16086	intact:EBI-15348306|ensembl:ENSRNOP00000023037	intact:EBI-2255997|uniprotkb:O88663|uniprotkb:P70477|ensembl:ENSRNOP00000042382	psi-mi:itm2b_rat(display_long)|uniprotkb:Itm2b(gene name)|psi-mi:Itm2b(display_short)|uniprotkb:Immature BRI2(gene name synonym)|uniprotkb:Transmembrane protein BRI(gene name synonym)	psi-mi:sptn1_rat(display_long)|uniprotkb:Sptan1(gene name)|psi-mi:Sptan1(display_short)|uniprotkb:Spna2(gene name synonym)|uniprotkb:Spta2(gene name synonym)|uniprotkb:Alpha-II spectrin(gene name synonym)|uniprotkb:Fodrin alpha chain(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Martins et al. (2018)	imex:IM-28469|pubmed:29476059	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26438079|imex:IM-28469-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSRNOG00000016271(gene)|ensembl:ENSRNOT00000023037(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001540"(amyloid-beta binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0010008"(endosome membrane)|go:"GO:0030660"(Golgi-associated vesicle membrane)|go:"GO:0031301"(integral component of organelle membrane)|go:"GO:0042985"(negative regulation of amyloid precursor protein biosynthetic process)|interpro:IPR007084(BRICHOS)|interpro:IPR040145|mint:Q5XIE8|refseq:NP_001006964.1|rgd:620727	rgd:621714|refseq:NP_741984.2|ensembl:ENSRNOG00000015396(gene)|ensembl:ENSRNOT00000045827(transcript)|go:"GO:0003779"(actin binding)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005916"(fascia adherens)|go:"GO:0008091"(spectrin)|go:"GO:0016020"(membrane)|go:"GO:0016328"(lateral plasma membrane)|go:"GO:0019905"(syntaxin binding)|go:"GO:0030018"(Z disc)|go:"GO:0030507"(spectrin binding)|go:"GO:0030863"(cortical cytoskeleton)|go:"GO:0031532"(actin cytoskeleton reorganization)|go:"GO:0032437"(cuticular plate)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033270"(paranode region of axon)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0051693"(actin filament capping)|interpro:IPR001452(Src homology-3)|interpro:IPR002017(Spectrin repeat)|interpro:IPR002048(Calcium-binding EF-hand)|interpro:IPR011992(EF-Hand type)|interpro:IPR014837(EF-hand, Ca insensitive)|interpro:IPR018159|interpro:IPR018247|interpro:IPR035825|interpro:IPR036028|mint:P16086|rcsb pdb:3THK|reactome:R-RNO-264870|reactome:R-RNO-375165|reactome:R-RNO-445095|reactome:R-RNO-5673001|reactome:R-RNO-6798695|reactome:R-RNO-6807878|reactome:R-RNO-9013420|reactome:R-RNO-9013424	-	-	-	figure legend:ST1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10116(rat-brain-cerebellum)|taxid:10116(Rattus norvegicus)	-	2020/10/30	2020/10/30	rogid:DtE+ZXAZKdCMvUW5K+jXQ5bH07M10116	rogid:3Tj95Pgv62omEnsaMAG3bfLLXsM10116	rigid:OaXQ9NA25fwCWxejPU3Ao9q5j/E	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q5XIE8	uniprotkb:P12346	intact:EBI-15348306|ensembl:ENSRNOP00000023037	intact:EBI-5748069|uniprotkb:Q63602|uniprotkb:Q64628|uniprotkb:Q64630|uniprotkb:Q7TNX0|ensembl:ENSRNOP00000045637	psi-mi:itm2b_rat(display_long)|uniprotkb:Itm2b(gene name)|psi-mi:Itm2b(display_short)|uniprotkb:Immature BRI2(gene name synonym)|uniprotkb:Transmembrane protein BRI(gene name synonym)	psi-mi:trfe_rat(display_long)|uniprotkb:Tf(gene name)|psi-mi:Tf(display_short)|uniprotkb:Beta-1 metal-binding globulin(gene name synonym)|uniprotkb:Liver regeneration-related protein LRRG03(gene name synonym)|uniprotkb:Siderophilin(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Martins et al. (2018)	imex:IM-28469|pubmed:29476059	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26438079|imex:IM-28469-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSRNOG00000016271(gene)|ensembl:ENSRNOT00000023037(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001540"(amyloid-beta binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0010008"(endosome membrane)|go:"GO:0030660"(Golgi-associated vesicle membrane)|go:"GO:0031301"(integral component of organelle membrane)|go:"GO:0042985"(negative regulation of amyloid precursor protein biosynthetic process)|interpro:IPR007084(BRICHOS)|interpro:IPR040145|mint:Q5XIE8|refseq:NP_001006964.1|rgd:620727	rgd:3845|refseq:NP_001013128.1|ensembl:ENSRNOG00000030625(gene)|ensembl:ENSRNOT00000045628(transcript)|go:"GO:0001666"(response to hypoxia)|go:"GO:0005576"(extracellular region)|go:"GO:0005604"(basement membrane)|go:"GO:0005615"(extracellular space)|go:"GO:0005768"(endosome)|go:"GO:0005769"(early endosome)|go:"GO:0005770"(late endosome)|go:"GO:0005886"(plasma membrane)|go:"GO:0005905"(clathrin-coated pit)|go:"GO:0006826"(iron ion transport)|go:"GO:0006879"(cellular iron ion homeostasis)|go:"GO:0006915"(apoptotic process)|go:"GO:0006953"(acute-phase response)|go:"GO:0007015"(actin filament organization)|go:"GO:0007257"(obsolete activation of JUN kinase activity)|go:"GO:0008198"(ferrous iron binding)|go:"GO:0008199"(ferric iron binding)|go:"GO:0009617"(response to bacterium)|go:"GO:0009925"(basal plasma membrane)|go:"GO:0009986"(cell surface)|go:"GO:0010288"(response to lead ion)|go:"GO:0014070"(response to organic cyclic compound)|go:"GO:0016020"(membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0019731"(antibacterial humoral response)|go:"GO:0030139"(endocytic vesicle)|go:"GO:0030316"(osteoclast differentiation)|go:"GO:0031232"(extrinsic component of external side of plasma membrane)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0031643"(positive regulation of myelination)|go:"GO:0031982"(vesicle)|go:"GO:0034756"(regulation of iron ion transport)|go:"GO:0034986"(iron chaperone activity)|go:"GO:0042327"(positive regulation of phosphorylation)|go:"GO:0045178"(basal part of cell)|go:"GO:0045780"(positive regulation of bone resorption)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0048260"(positive regulation of receptor-mediated endocytosis)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051286"(cell tip)|go:"GO:0055037"(recycling endosome)|go:"GO:0060395"(SMAD protein signal transduction)|go:"GO:0070371"(ERK1 and ERK2 cascade)|go:"GO:0070447"(positive regulation of oligodendrocyte progenitor proliferation)|go:"GO:0071281"(cellular response to iron ion)|go:"GO:0071320"(cellular response to cAMP)|go:"GO:0071372"(cellular response to follicle-stimulating hormone stimulus)|go:"GO:1990459"(transferrin receptor binding)|go:"GO:1990712"(HFE-transferrin receptor complex)|go:"GO:2000147"(positive regulation of cell motility)|interpro:IPR001156(Peptidase S60, transferrin lactoferrin)|interpro:IPR016357(Transferrin)|interpro:IPR018195|interpro:IPR030685|mint:P12346|reactome:R-RNO-114608|reactome:R-RNO-381426|reactome:R-RNO-8856825|reactome:R-RNO-8856828|reactome:R-RNO-8957275|reactome:R-RNO-917937|reactome:R-RNO-917977	-	-	-	figure legend:ST1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10116(rat-brain-cerebellum)|taxid:10116(Rattus norvegicus)	-	2020/10/30	2020/10/30	rogid:DtE+ZXAZKdCMvUW5K+jXQ5bH07M10116	rogid:9b+8HnYQbOkvBtuNUgHzhq2+cQ010116	rigid:OaXQ9NA25fwCWxejPU3Ao9q5j/E	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q5XIE8	uniprotkb:Q6RJR6	intact:EBI-15348306|ensembl:ENSRNOP00000023037	intact:EBI-919246|uniprotkb:Q6P6R3|uniprotkb:Q8VBU0|ensembl:ENSRNOP00000028785	psi-mi:itm2b_rat(display_long)|uniprotkb:Itm2b(gene name)|psi-mi:Itm2b(display_short)|uniprotkb:Immature BRI2(gene name synonym)|uniprotkb:Transmembrane protein BRI(gene name synonym)	psi-mi:rtn3_rat(display_long)|uniprotkb:Rtn3(gene name)|psi-mi:Rtn3(display_short)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Martins et al. (2018)	imex:IM-28469|pubmed:29476059	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26438079|imex:IM-28469-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSRNOG00000016271(gene)|ensembl:ENSRNOT00000023037(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001540"(amyloid-beta binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0010008"(endosome membrane)|go:"GO:0030660"(Golgi-associated vesicle membrane)|go:"GO:0031301"(integral component of organelle membrane)|go:"GO:0042985"(negative regulation of amyloid precursor protein biosynthetic process)|interpro:IPR007084(BRICHOS)|interpro:IPR040145|mint:Q5XIE8|refseq:NP_001006964.1|rgd:620727	rgd:620988|refseq:NP_001009953.2|refseq:NP_543185.2|ensembl:ENSRNOG00000021202(gene)|ensembl:ENSRNOT00000028785(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0006915"(apoptotic process)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016192"(vesicle-mediated transport)|go:"GO:0045202"(synapse)|go:"GO:0071786"(endoplasmic reticulum tubular network organization)|go:"GO:0071787"(endoplasmic reticulum tubular network formation)|go:"GO:1902430"(negative regulation of amyloid-beta formation)|interpro:IPR003388(Reticulon)|mint:Q6RJR6|reactome:R-RNO-8849932	-	-	-	figure legend:ST1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10116(rat-brain-cerebellum)|taxid:10116(Rattus norvegicus)	-	2020/10/30	2020/10/30	rogid:DtE+ZXAZKdCMvUW5K+jXQ5bH07M10116	rogid:CehbzFUmpJjUrA42+RLJ+oKmx3A10116	rigid:OaXQ9NA25fwCWxejPU3Ao9q5j/E	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q5XIE8	uniprotkb:Q64548	intact:EBI-15348306|ensembl:ENSRNOP00000023037	intact:EBI-26437852|uniprotkb:Q64547	psi-mi:itm2b_rat(display_long)|uniprotkb:Itm2b(gene name)|psi-mi:Itm2b(display_short)|uniprotkb:Immature BRI2(gene name synonym)|uniprotkb:Transmembrane protein BRI(gene name synonym)	psi-mi:rtn1_rat(display_long)|uniprotkb:Rtn1(gene name)|psi-mi:Rtn1(display_short)|uniprotkb:Nsp(gene name synonym)|uniprotkb:Neuroendocrine-specific protein(gene name synonym)|uniprotkb:S-rex(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Martins et al. (2018)	imex:IM-28469|pubmed:29476059	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26438079|imex:IM-28469-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSRNOG00000016271(gene)|ensembl:ENSRNOT00000023037(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001540"(amyloid-beta binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0010008"(endosome membrane)|go:"GO:0030660"(Golgi-associated vesicle membrane)|go:"GO:0031301"(integral component of organelle membrane)|go:"GO:0042985"(negative regulation of amyloid precursor protein biosynthetic process)|interpro:IPR007084(BRICHOS)|interpro:IPR040145|mint:Q5XIE8|refseq:NP_001006964.1|rgd:620727	go:"GO:0000139"(Golgi membrane)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005790"(smooth endoplasmic reticulum)|go:"GO:0016021"(integral component of membrane)|go:"GO:1902430"(negative regulation of amyloid-beta formation)|mint:Q64548|refseq:NP_446317.1|refseq:XP_008762912.1|interpro:IPR003388(Reticulon)|rgd:620986	-	-	-	figure legend:ST1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10116(rat-brain-cerebellum)|taxid:10116(Rattus norvegicus)	-	2020/10/30	2020/10/30	rogid:DtE+ZXAZKdCMvUW5K+jXQ5bH07M10116	rogid:GR15tCaopATHPIxGwl20b04sG4c10116	rigid:OaXQ9NA25fwCWxejPU3Ao9q5j/E	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q5XIE8	uniprotkb:P63012	intact:EBI-15348306|ensembl:ENSRNOP00000023037	intact:EBI-440126|ensembl:ENSRNOP00000026392|uniprotkb:P05713	psi-mi:itm2b_rat(display_long)|uniprotkb:Itm2b(gene name)|psi-mi:Itm2b(display_short)|uniprotkb:Immature BRI2(gene name synonym)|uniprotkb:Transmembrane protein BRI(gene name synonym)	psi-mi:rab3a_rat(display_long)|uniprotkb:Rab3a(gene name)|psi-mi:Rab3a(display_short)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Martins et al. (2018)	imex:IM-28469|pubmed:29476059	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26438079|imex:IM-28469-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSRNOG00000016271(gene)|ensembl:ENSRNOT00000023037(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001540"(amyloid-beta binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0010008"(endosome membrane)|go:"GO:0030660"(Golgi-associated vesicle membrane)|go:"GO:0031301"(integral component of organelle membrane)|go:"GO:0042985"(negative regulation of amyloid precursor protein biosynthetic process)|interpro:IPR007084(BRICHOS)|interpro:IPR040145|mint:Q5XIE8|refseq:NP_001006964.1|rgd:620727	ensembl:ENSRNOT00000026391(transcript)|go:"GO:0001669"(acrosomal vesicle)|go:"GO:0001671"(ATPase activator activity)|go:"GO:0001778"(plasma membrane repair)|go:"GO:0003016"(respiratory system process)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005764"(lysosome)|go:"GO:0005768"(endosome)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006887"(exocytosis)|go:"GO:0006904"(vesicle docking involved in exocytosis)|go:"GO:0007005"(mitochondrion organization)|go:"GO:0007274"(neuromuscular synaptic transmission)|go:"GO:0007409"(axonogenesis)|ensembl:ENSRNOG00000019433(gene)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0009306"(protein secretion)|go:"GO:0009791"(post-embryonic development)|go:"GO:0010807"(regulation of synaptic vesicle priming)|go:"GO:0014059"(regulation of dopamine secretion)|go:"GO:0016020"(membrane)|go:"GO:0016079"(synaptic vesicle exocytosis)|go:"GO:0016188"(synaptic vesicle maturation)|go:"GO:0017156"(calcium-ion regulated exocytosis)|go:"GO:0017157"(regulation of exocytosis)|go:"GO:0030141"(secretory granule)|go:"GO:0030324"(lung development)|go:"GO:0030424"(axon)|go:"GO:0030742"(GTP-dependent protein binding)|go:"GO:0031489"(myosin V binding)|go:"GO:0031630"(regulation of synaptic vesicle fusion to presynaptic active zone membrane)|go:"GO:0032418"(lysosome localization)|go:"GO:0032482"(Rab protein signal transduction)|go:"GO:0032991"(protein-containing complex)|go:"GO:0036465"(synaptic vesicle recycling)|go:"GO:0043195"(terminal bouton)|go:"GO:0043229"(intracellular organelle)|go:"GO:0045055"(regulated exocytosis)|go:"GO:0048172"(regulation of short-term neuronal synaptic plasticity)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0048489"(synaptic vesicle transport)|go:"GO:0048786"(presynaptic active zone)|go:"GO:0048790"(maintenance of presynaptic active zone structure)|go:"GO:0050975"(sensory perception of touch)|go:"GO:0051021"(GDP-dissociation inhibitor binding)|go:"GO:0051117"(ATPase binding)|go:"GO:0060478"(acrosomal vesicle exocytosis)|go:"GO:0061670"(evoked neurotransmitter secretion)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0097091"(synaptic vesicle clustering)|go:"GO:0098993"(anchored component of synaptic vesicle membrane)|go:"GO:1903307"(positive regulation of regulated secretory pathway)|go:"GO:1905684"(regulation of plasma membrane repair)|go:"GO:2000300"(regulation of synaptic vesicle exocytosis)|interpro:IPR001806(Ras GTPase)|interpro:IPR005225(Small GTP-binding protein)|interpro:IPR027417|interpro:IPR037872|mint:P63012|rcsb pdb:1ZBD|rcsb pdb:3RAB|reactome:R-RNO-181429|reactome:R-RNO-181430|reactome:R-RNO-210500|reactome:R-RNO-212676|reactome:R-RNO-264642|reactome:R-RNO-6798695|reactome:R-RNO-8873719|reactome:R-RNO-8876198|reactome:R-RNO-888590|go:"GO:0051602"(response to electrical stimulus)|rgd:3528|refseq:NP_037150.2	-	-	-	figure legend:ST1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10116(rat-brain-cerebellum)|taxid:10116(Rattus norvegicus)	-	2020/10/30	2020/10/30	rogid:DtE+ZXAZKdCMvUW5K+jXQ5bH07M10116	rogid:Skrsn0x0LP/jAuOk1LQ4ataeiDA10116	rigid:OaXQ9NA25fwCWxejPU3Ao9q5j/E	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q5XIE8	uniprotkb:P63319	intact:EBI-15348306|ensembl:ENSRNOP00000023037	intact:EBI-12598030|ensembl:ENSRNOP00000071203|uniprotkb:P05697|uniprotkb:Q5FWS3	psi-mi:itm2b_rat(display_long)|uniprotkb:Itm2b(gene name)|psi-mi:Itm2b(display_short)|uniprotkb:Immature BRI2(gene name synonym)|uniprotkb:Transmembrane protein BRI(gene name synonym)	psi-mi:kpcg_rat(display_long)|uniprotkb:Prkcg(gene name)|psi-mi:Prkcg(display_short)|uniprotkb:Pkcc(gene name synonym)|uniprotkb:Pkcg(gene name synonym)|uniprotkb:Prkcc(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Martins et al. (2018)	imex:IM-28469|pubmed:29476059	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26438079|imex:IM-28469-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSRNOG00000016271(gene)|ensembl:ENSRNOT00000023037(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001540"(amyloid-beta binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0010008"(endosome membrane)|go:"GO:0030660"(Golgi-associated vesicle membrane)|go:"GO:0031301"(integral component of organelle membrane)|go:"GO:0042985"(negative regulation of amyloid precursor protein biosynthetic process)|interpro:IPR007084(BRICHOS)|interpro:IPR040145|mint:Q5XIE8|refseq:NP_001006964.1|rgd:620727	ensembl:ENSRNOG00000054371(gene)|ensembl:ENSRNOT00000080032(transcript)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0004697"(protein kinase C activity)|go:"GO:0004698"(calcium-dependent protein kinase C activity)|go:"GO:0004712"(protein serine/threonine/tyrosine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0007268"(chemical synaptic transmission)|go:"GO:0007611"(learning or memory)|go:"GO:0007635"(chemosensory behavior)|go:"GO:0008270"(zinc ion binding)|go:"GO:0009636"(response to toxic substance)|go:"GO:0014069"(postsynaptic density)|go:"GO:0016020"(membrane)|go:"GO:0016310"(phosphorylation)|go:"GO:0018105"(peptidyl-serine phosphorylation)|go:"GO:0030425"(dendrite)|go:"GO:0031397"(negative regulation of protein ubiquitination)|go:"GO:0032095"(regulation of response to food)|go:"GO:0032425"(positive regulation of mismatch repair)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0042177"(negative regulation of protein catabolic process)|go:"GO:0042752"(regulation of circadian rhythm)|go:"GO:0043005"(neuron projection)|go:"GO:0043278"(response to morphine)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0044305"(calyx of Held)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0048265"(response to pain)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0048511"(rhythmic process)|go:"GO:0050764"(regulation of phagocytosis)|go:"GO:0060291"(long-term synaptic potentiation)|go:"GO:0060384"(innervation)|go:"GO:0097060"(synaptic membrane)|go:"GO:0099171"(presynaptic modulation of chemical synaptic transmission)|go:"GO:0099523"(presynaptic cytosol)|go:"GO:0099524"(postsynaptic cytosol)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:1901799"(negative regulation of proteasomal protein catabolic process)|go:"GO:1990911"(response to psychosocial stress)|go:"GO:2000300"(regulation of synaptic vesicle exocytosis)|interpro:IPR000008(C2 calcium-dependent membrane targeting)|interpro:IPR000719(Protein kinase, core)|interpro:IPR000961(Protein kinase, C-terminal)|interpro:IPR002219(Protein kinase C, phorbol ester/diacylglycerol binding)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR014375(Protein kinase C, alpha/beta/gamma types)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR017892|interpro:IPR020454|interpro:IPR035892|mint:P63319|rcsb pdb:1TBN|rcsb pdb:1TBO|reactome:R-RNO-111933|reactome:R-RNO-114516|reactome:R-RNO-416993|reactome:R-RNO-5099900|reactome:R-RNO-76005|rgd:3397|refseq:NP_036760.1	-	-	-	figure legend:ST1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10116(rat-brain-cerebellum)|taxid:10116(Rattus norvegicus)	-	2020/10/30	2020/10/30	rogid:DtE+ZXAZKdCMvUW5K+jXQ5bH07M10116	rogid:t4ukCPPAnYUtHCH1hnQE+uiyfEM10116	rigid:OaXQ9NA25fwCWxejPU3Ao9q5j/E	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q5XIE8	uniprotkb:Q5XIH7	intact:EBI-15348306|ensembl:ENSRNOP00000023037	intact:EBI-918041|uniprotkb:P70629|uniprotkb:P70630|ensembl:ENSRNOP00000017472	psi-mi:itm2b_rat(display_long)|uniprotkb:Itm2b(gene name)|psi-mi:Itm2b(display_short)|uniprotkb:Immature BRI2(gene name synonym)|uniprotkb:Transmembrane protein BRI(gene name synonym)	psi-mi:phb2_rat(display_long)|uniprotkb:B-cell receptor-associated protein BAP37(gene name synonym)|uniprotkb:Phb2(gene name)|psi-mi:Phb2(display_short)|uniprotkb:Bcap37(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Martins et al. (2018)	imex:IM-28469|pubmed:29476059	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26438079|imex:IM-28469-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSRNOG00000016271(gene)|ensembl:ENSRNOT00000023037(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001540"(amyloid-beta binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0010008"(endosome membrane)|go:"GO:0030660"(Golgi-associated vesicle membrane)|go:"GO:0031301"(integral component of organelle membrane)|go:"GO:0042985"(negative regulation of amyloid precursor protein biosynthetic process)|interpro:IPR007084(BRICHOS)|interpro:IPR040145|mint:Q5XIE8|refseq:NP_001006964.1|rgd:620727	rgd:620203|refseq:NP_001013053.1|ensembl:ENSRNOG00000012999(gene)|ensembl:ENSRNOT00000017472(transcript)|go:"GO:0000423"(mitophagy)|go:"GO:0002639"(positive regulation of immunoglobulin production)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005886"(plasma membrane)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0007005"(mitochondrion organization)|go:"GO:0007062"(sister chromatid cohesion)|go:"GO:0007202"(activation of phospholipase C activity)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0009611"(response to wounding)|go:"GO:0009986"(cell surface)|go:"GO:0016363"(nuclear matrix)|go:"GO:0016477"(cell migration)|go:"GO:0023035"(CD40 signaling pathway)|go:"GO:0031536"(positive regulation of exit from mitosis)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033147"(negative regulation of intracellular estrogen receptor signaling pathway)|go:"GO:0033218"(amide binding)|go:"GO:0033600"(negative regulation of mammary gland epithelial cell proliferation)|go:"GO:0035632"(mitochondrial prohibitin complex)|go:"GO:0039520"(induction by virus of host autophagy)|go:"GO:0039529"(RIG-I signaling pathway)|go:"GO:0042113"(B cell activation)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043433"(negative regulation of DNA-binding transcription factor activity)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0046625"(sphingolipid binding)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0047485"(protein N-terminus binding)|go:"GO:0048786"(presynaptic active zone)|go:"GO:0050821"(protein stabilization)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0060744"(mammary gland branching involved in thelarche)|go:"GO:0060749"(mammary gland alveolus development)|go:"GO:0060762"(regulation of branching involved in mammary gland duct morphogenesis)|go:"GO:0070374"(positive regulation of ERK1 and ERK2 cascade)|go:"GO:0071300"(cellular response to retinoic acid)|go:"GO:0071456"(cellular response to hypoxia)|go:"GO:0071944"(cell periphery)|go:"GO:0098800"(inner mitochondrial membrane protein complex)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0098982"(GABA-ergic synapse)|go:"GO:0140374"(antiviral innate immune response)|go:"GO:1900208"(regulation of cardiolipin metabolic process)|go:"GO:1901224"(positive regulation of NIK/NF-kappaB signaling)|go:"GO:1902808"(positive regulation of cell cycle G1/S phase transition)|go:"GO:1904959"(regulation of cytochrome-c oxidase activity)|go:"GO:1990051"(activation of protein kinase C activity)|interpro:IPR000163(Prohibitin)|interpro:IPR001107(Band 7 protein)|interpro:IPR036013|mint:Q5XIH7|reactome:R-RNO-8949664|go:"GO:0014069"(postsynaptic density)	-	-	-	figure legend:ST1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10116(rat-brain-cerebellum)|taxid:10116(Rattus norvegicus)	-	2020/10/30	2020/10/30	rogid:DtE+ZXAZKdCMvUW5K+jXQ5bH07M10116	rogid:VjRorTWSSei7yX+hNlgLqK2S49810116	rigid:OaXQ9NA25fwCWxejPU3Ao9q5j/E	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q5XIE8	uniprotkb:P67779	intact:EBI-15348306|ensembl:ENSRNOP00000023037	intact:EBI-298513|uniprotkb:P24142|uniprotkb:Q4V8M6|ensembl:ENSRNOP00000066502	psi-mi:itm2b_rat(display_long)|uniprotkb:Itm2b(gene name)|psi-mi:Itm2b(display_short)|uniprotkb:Immature BRI2(gene name synonym)|uniprotkb:Transmembrane protein BRI(gene name synonym)	psi-mi:phb_rat(display_long)|uniprotkb:Phb(gene name)|psi-mi:Phb(display_short)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Martins et al. (2018)	imex:IM-28469|pubmed:29476059	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26438079|imex:IM-28469-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSRNOG00000016271(gene)|ensembl:ENSRNOT00000023037(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001540"(amyloid-beta binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0010008"(endosome membrane)|go:"GO:0030660"(Golgi-associated vesicle membrane)|go:"GO:0031301"(integral component of organelle membrane)|go:"GO:0042985"(negative regulation of amyloid precursor protein biosynthetic process)|interpro:IPR007084(BRICHOS)|interpro:IPR040145|mint:Q5XIE8|refseq:NP_001006964.1|rgd:620727	go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005737"(cytoplasm)|go:"GO:0005769"(early endosome)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0007005"(mitochondrion organization)|go:"GO:0007202"(activation of phospholipase C activity)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0009986"(cell surface)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010942"(positive regulation of cell death)|go:"GO:0010944"(negative regulation of transcription by competitive promoter binding)|go:"GO:0014069"(postsynaptic density)|go:"GO:0016575"(histone deacetylation)|go:"GO:0019899"(enzyme binding)|go:"GO:0023035"(CD40 signaling pathway)|go:"GO:0030061"(mitochondrial crista)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0031100"(animal organ regeneration)|go:"GO:0031315"(extrinsic component of mitochondrial outer membrane)|go:"GO:0031871"(proteinase activated receptor binding)|go:"GO:0032740"(positive regulation of interleukin-17 production)|go:"GO:0034097"(response to cytokine)|go:"GO:0035632"(mitochondrial prohibitin complex)|go:"GO:0035902"(response to immobilization stress)|go:"GO:0039529"(RIG-I signaling pathway)|go:"GO:0042113"(B cell activation)|go:"GO:0042177"(negative regulation of protein catabolic process)|go:"GO:0042493"|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043434"(response to peptide hormone)|go:"GO:0044830"(modulation by host of viral RNA genome replication)|go:"GO:0045471"(response to ethanol)|go:"GO:0045745"(positive regulation of G protein-coupled receptor signaling pathway)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045917"(positive regulation of complement activation)|go:"GO:0046718"(viral entry into host cell)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0048661"(positive regulation of smooth muscle cell proliferation)|go:"GO:0050821"(protein stabilization)|go:"GO:0050847"(progesterone receptor signaling pathway)|go:"GO:0051897"(positive regulation of protein kinase B signaling)|go:"GO:0060766"(negative regulation of androgen receptor signaling pathway)|go:"GO:0070373"(negative regulation of ERK1 and ERK2 cascade)|go:"GO:0070374"(positive regulation of ERK1 and ERK2 cascade)|go:"GO:0071354"(cellular response to interleukin-6)|go:"GO:0071897"(DNA biosynthetic process)|go:"GO:0072538"(T-helper 17 type immune response)|go:"GO:0098891"(extrinsic component of presynaptic active zone membrane)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0042826"(histone deacetylase binding)|ensembl:ENSRNOG00000046799(gene)|ensembl:ENSRNOT00000075733(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0001541"(ovarian follicle development)|go:"GO:0001552"(ovarian follicle atresia)|go:"GO:0001850"(complement component C3a binding)|go:"GO:0001851"(complement component C3b binding)|go:"GO:0002639"(positive regulation of immunoglobulin production)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0140374"(antiviral innate immune response)|go:"GO:1901224"(positive regulation of NIK/NF-kappaB signaling)|go:"GO:1990051"(activation of protein kinase C activity)|go:"GO:2000323"(negative regulation of glucocorticoid receptor signaling pathway)|interpro:IPR000163(Prohibitin)|interpro:IPR001107(Band 7 protein)|go:"GO:0098982"(GABA-ergic synapse)|interpro:IPR036013|mint:P67779|reactome:R-RNO-5673000|reactome:R-RNO-8949664|rgd:3322|refseq:NP_114039.1	-	-	-	figure legend:ST1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10116(rat-brain-cerebellum)|taxid:10116(Rattus norvegicus)	-	2020/10/30	2020/10/30	rogid:DtE+ZXAZKdCMvUW5K+jXQ5bH07M10116	rogid:eUStcZ9Mu7+7MHr/GJXFwwJY/Fc10116	rigid:OaXQ9NA25fwCWxejPU3Ao9q5j/E	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q5XIE8	uniprotkb:P19527	intact:EBI-15348306|ensembl:ENSRNOP00000023037	intact:EBI-446360|uniprotkb:Q63367|ensembl:ENSRNOP00000018599	psi-mi:itm2b_rat(display_long)|uniprotkb:Itm2b(gene name)|psi-mi:Itm2b(display_short)|uniprotkb:Immature BRI2(gene name synonym)|uniprotkb:Transmembrane protein BRI(gene name synonym)	psi-mi:nfl_rat(display_long)|uniprotkb:Neurofilament triplet L protein(gene name synonym)|uniprotkb:68 kDa neurofilament protein(gene name synonym)|uniprotkb:Nefl(gene name)|psi-mi:Nefl(display_short)|uniprotkb:Nf68(gene name synonym)|uniprotkb:Nfl(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Martins et al. (2018)	imex:IM-28469|pubmed:29476059	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26438079|imex:IM-28469-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSRNOG00000016271(gene)|ensembl:ENSRNOT00000023037(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001540"(amyloid-beta binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0010008"(endosome membrane)|go:"GO:0030660"(Golgi-associated vesicle membrane)|go:"GO:0031301"(integral component of organelle membrane)|go:"GO:0042985"(negative regulation of amyloid precursor protein biosynthetic process)|interpro:IPR007084(BRICHOS)|interpro:IPR040145|mint:Q5XIE8|refseq:NP_001006964.1|rgd:620727	rgd:621458|refseq:NP_113971.1|dip:DIP-1N|ensembl:ENSRNOG00000013658(gene)|ensembl:ENSRNOT00000018599(transcript)|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0005200"(structural constituent of cytoskeleton)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005882"(intermediate filament)|go:"GO:0005883"(neurofilament)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008089"(anterograde axonal transport)|go:"GO:0008090"(retrograde axonal transport)|go:"GO:0009636"(response to toxic substance)|go:"GO:0010033"(response to organic substance)|go:"GO:0014012"(peripheral nervous system axon regeneration)|go:"GO:0019896"(axonal transport of mitochondrion)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0021510"(spinal cord development)|go:"GO:0021766"(hippocampus development)|go:"GO:0021987"(cerebral cortex development)|go:"GO:0030424"(axon)|go:"GO:0030426"(growth cone)|go:"GO:0030674"(protein-macromolecule adaptor activity)|go:"GO:0031133"(regulation of axon diameter)|go:"GO:0031594"(neuromuscular junction)|go:"GO:0033693"(neurofilament bundle assembly)|go:"GO:0040011"(locomotion)|go:"GO:0042802"(identical protein binding)|go:"GO:0043005"(neuron projection)|go:"GO:0043274"(phospholipase binding)|go:"GO:0043434"(response to peptide hormone)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045105"(intermediate filament polymerization or depolymerization)|go:"GO:0045109"(intermediate filament organization)|go:"GO:0045110"(intermediate filament bundle assembly)|go:"GO:0048812"(neuron projection morphogenesis)|go:"GO:0050772"(positive regulation of axonogenesis)|go:"GO:0050885"(neuromuscular process controlling balance)|go:"GO:0051258"(protein polymerization)|go:"GO:0051412"(response to corticosterone)|go:"GO:0060052"(neurofilament cytoskeleton organization)|go:"GO:0060074"(synapse maturation)|go:"GO:0098685"(Schaffer collateral - CA1 synapse)|go:"GO:0098981"(cholinergic synapse)|go:"GO:0099182"(presynaptic intermediate filament cytoskeleton)|go:"GO:0099184"(structural constituent of postsynaptic intermediate filament cytoskeleton)|go:"GO:1903935"(response to sodium arsenite)|go:"GO:1903937"(response to acrylamide)|go:"GO:0099160"(postsynaptic intermediate filament cytoskeleton)|go:"GO:1904115"(axon cytoplasm)|interpro:IPR006821(Intermediate filament, DNA-binding region)|interpro:IPR018039|interpro:IPR027692|interpro:IPR039008|mint:P19527|reactome:R-RNO-438066|reactome:R-RNO-5673001	-	-	-	figure legend:ST1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10116(rat-brain-cerebellum)|taxid:10116(Rattus norvegicus)	-	2020/10/30	2020/10/30	rogid:DtE+ZXAZKdCMvUW5K+jXQ5bH07M10116	rogid:j/u8VG9hdvpMSY4/bU7l4hxX41Q10116	rigid:OaXQ9NA25fwCWxejPU3Ao9q5j/E	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q5XIE8	uniprotkb:P16884	intact:EBI-15348306|ensembl:ENSRNOP00000023037	intact:EBI-446344|uniprotkb:O35482|uniprotkb:Q540Z7|uniprotkb:Q63368	psi-mi:itm2b_rat(display_long)|uniprotkb:Itm2b(gene name)|psi-mi:Itm2b(display_short)|uniprotkb:Immature BRI2(gene name synonym)|uniprotkb:Transmembrane protein BRI(gene name synonym)	psi-mi:nfh_rat(display_long)|uniprotkb:Neurofilament triplet H protein(gene name synonym)|uniprotkb:200 kDa neurofilament protein(gene name synonym)|uniprotkb:Nefh(gene name)|psi-mi:Nefh(display_short)|uniprotkb:Nfh(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Martins et al. (2018)	imex:IM-28469|pubmed:29476059	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26438079|imex:IM-28469-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSRNOG00000016271(gene)|ensembl:ENSRNOT00000023037(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001540"(amyloid-beta binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0010008"(endosome membrane)|go:"GO:0030660"(Golgi-associated vesicle membrane)|go:"GO:0031301"(integral component of organelle membrane)|go:"GO:0042985"(negative regulation of amyloid precursor protein biosynthetic process)|interpro:IPR007084(BRICHOS)|interpro:IPR040145|mint:Q5XIE8|refseq:NP_001006964.1|rgd:620727	rgd:3159|dip:DIP-105N|mint:P16884|go:"GO:0007420"(brain development)|go:"GO:0014069"(postsynaptic density)|go:"GO:0015643"(toxic substance binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0021510"(spinal cord development)|go:"GO:0021766"(hippocampus development)|go:"GO:0021987"(cerebral cortex development)|go:"GO:0030424"(axon)|go:"GO:0030674"(protein-macromolecule adaptor activity)|go:"GO:0031103"(axon regeneration)|go:"GO:0031175"(neuron projection development)|go:"GO:0033693"(neurofilament bundle assembly)|go:"GO:0034599"(cellular response to oxidative stress)|go:"GO:0042220"(response to cocaine)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043204"(perikaryon)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045104"(intermediate filament cytoskeleton organization)|go:"GO:0045110"(intermediate filament bundle assembly)|go:"GO:0048936"(peripheral nervous system neuron axonogenesis)|go:"GO:0060052"(neurofilament cytoskeleton organization)|go:"GO:0061564"(axon development)|go:"GO:0071392"(cellular response to estradiol stimulus)|go:"GO:0071447"(cellular response to hydroperoxide)|go:"GO:0097418"(neurofibrillary tangle)|go:"GO:0097440"(apical dendrite)|go:"GO:0098685"(Schaffer collateral - CA1 synapse)|go:"GO:0099160"(postsynaptic intermediate filament cytoskeleton)|go:"GO:0099184"(structural constituent of postsynaptic intermediate filament cytoskeleton)|go:"GO:0150017"(basal proximal dendrite)|go:"GO:1902513"(regulation of organelle transport along microtubule)|go:"GO:1903935"(response to sodium arsenite)|go:"GO:1903937"(response to acrylamide)|go:"GO:1990830"(cellular response to leukemia inhibitory factor)|interpro:IPR010790(Protein of unknown function DUF1388)|interpro:IPR018039|interpro:IPR033183|interpro:IPR039008|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0001552"(ovarian follicle atresia)|go:"GO:0005200"(structural constituent of cytoskeleton)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005882"(intermediate filament)|go:"GO:0005883"(neurofilament)	-	-	-	figure legend:ST1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10116(rat-brain-cerebellum)|taxid:10116(Rattus norvegicus)	-	2020/10/30	2020/10/30	rogid:DtE+ZXAZKdCMvUW5K+jXQ5bH07M10116	rogid:ouBvM47wkf3tA9ZWmjX5jObpZtE10116	rigid:OaXQ9NA25fwCWxejPU3Ao9q5j/E	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q5XIE8	uniprotkb:P97685	intact:EBI-15348306|ensembl:ENSRNOP00000023037	intact:EBI-26437804|ensembl:ENSRNOP00000057594|uniprotkb:P97684|uniprotkb:Q91Z60	psi-mi:itm2b_rat(display_long)|uniprotkb:Itm2b(gene name)|psi-mi:Itm2b(display_short)|uniprotkb:Immature BRI2(gene name synonym)|uniprotkb:Transmembrane protein BRI(gene name synonym)	psi-mi:nfasc_rat(display_long)|uniprotkb:Nfasc(gene name)|psi-mi:Nfasc(display_short)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Martins et al. (2018)	imex:IM-28469|pubmed:29476059	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26438079|imex:IM-28469-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSRNOG00000016271(gene)|ensembl:ENSRNOT00000023037(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001540"(amyloid-beta binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0010008"(endosome membrane)|go:"GO:0030660"(Golgi-associated vesicle membrane)|go:"GO:0031301"(integral component of organelle membrane)|go:"GO:0042985"(negative regulation of amyloid precursor protein biosynthetic process)|interpro:IPR007084(BRICHOS)|interpro:IPR040145|mint:Q5XIE8|refseq:NP_001006964.1|rgd:620727	go:"GO:0019904"(protein domain specific binding)|ensembl:ENSRNOG00000030515(gene)|go:"GO:0030424"(axon)|ensembl:ENSRNOT00000060871(transcript)|go:"GO:0002175"(protein localization to paranode region of axon)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0005918"(septate junction)|go:"GO:0007411"(axon guidance)|go:"GO:0007422"(peripheral nervous system development)|go:"GO:0019226"(transmission of nerve impulse)|go:"GO:0030425"(dendrite)|go:"GO:0030913"(paranodal junction assembly)|go:"GO:0033010"(paranodal junction)|go:"GO:0033268"(node of Ranvier)|go:"GO:0033270"(paranode region of axon)|go:"GO:0042552"(myelination)|go:"GO:0043194"(axon initial segment)|go:"GO:0045162"(clustering of voltage-gated sodium channels)|go:"GO:0050808"(synapse organization)|go:"GO:0071205"(protein localization to juxtaparanode region of axon)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0086080"(protein binding involved in heterotypic cell-cell adhesion)|go:"GO:0097454"(Schwann cell microvillus)|interpro:IPR003598(Immunoglobulin subtype 2)|interpro:IPR003599(Immunoglobulin subtype)|interpro:IPR003961(Fibronectin, type III)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR013098(Immunoglobulin I-set)|interpro:IPR013151(Immunoglobulin)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR026965|interpro:IPR026966|interpro:IPR036116|interpro:IPR036179|interpro:IPR043204|mint:P97685|reactome:R-RNO-447043|reactome:R-RNO-6798695|refseq:NP_001153785.1|refseq:NP_001153786.1|refseq:NP_446361.1|rgd:620911	-	-	-	figure legend:ST1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10116(rat-brain-cerebellum)|taxid:10116(Rattus norvegicus)	-	2020/10/30	2020/10/30	rogid:DtE+ZXAZKdCMvUW5K+jXQ5bH07M10116	rogid:HzCYcx8+shkIPZAc7h3T3dYDxDc10116	rigid:OaXQ9NA25fwCWxejPU3Ao9q5j/E	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q5XIE8	uniprotkb:P55067	intact:EBI-15348306|ensembl:ENSRNOP00000023037	intact:EBI-26437766	psi-mi:itm2b_rat(display_long)|uniprotkb:Itm2b(gene name)|psi-mi:Itm2b(display_short)|uniprotkb:Immature BRI2(gene name synonym)|uniprotkb:Transmembrane protein BRI(gene name synonym)	psi-mi:ncan_rat(display_long)|uniprotkb:Ncan(gene name)|psi-mi:Ncan(display_short)|uniprotkb:Cspg3(gene name synonym)|uniprotkb:245 kDa early postnatal core glycoprotein(gene name synonym)|uniprotkb:Chondroitin sulfate proteoglycan 3(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Martins et al. (2018)	imex:IM-28469|pubmed:29476059	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26438079|imex:IM-28469-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSRNOG00000016271(gene)|ensembl:ENSRNOT00000023037(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001540"(amyloid-beta binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0010008"(endosome membrane)|go:"GO:0030660"(Golgi-associated vesicle membrane)|go:"GO:0031301"(integral component of organelle membrane)|go:"GO:0042985"(negative regulation of amyloid precursor protein biosynthetic process)|interpro:IPR007084(BRICHOS)|interpro:IPR040145|mint:Q5XIE8|refseq:NP_001006964.1|rgd:620727	go:"GO:0001501"(skeletal system development)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005540"(hyaluronic acid binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005886"(plasma membrane)|go:"GO:0007155"(cell adhesion)|go:"GO:0007417"(central nervous system development)|go:"GO:0030246"(carbohydrate binding)|go:"GO:0031012"(extracellular matrix)|go:"GO:0045202"(synapse)|go:"GO:0051823"(regulation of synapse structural plasticity)|go:"GO:0072534"(perineuronal net)|reactome:R-RNO-1971475|reactome:R-RNO-2022870|reactome:R-RNO-2022923|reactome:R-RNO-2024101|reactome:R-RNO-3000178|mint:P55067|interpro:IPR001304(C-type lectin)|interpro:IPR016186(C-type lectin-like)|interpro:IPR018378|interpro:IPR016187(C-type lectin fold)|interpro:IPR001881(EGF-like calcium-binding)|interpro:IPR000742(EGF-like, type 3)|interpro:IPR000152(Aspartic acid and asparagine hydroxylation site)|interpro:IPR018097|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR036179|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR003599(Immunoglobulin subtype)|interpro:IPR013106(Immunoglobulin V-set)|interpro:IPR000538(Link)|interpro:IPR035976|interpro:IPR000436(Sushi/SCR/CCP)|rgd:619941	-	-	-	figure legend:ST1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10116(rat-brain-cerebellum)|taxid:10116(Rattus norvegicus)	-	2020/10/30	2020/10/30	rogid:DtE+ZXAZKdCMvUW5K+jXQ5bH07M10116	rogid:2/ICeFV747SqaUpp9GStWXPuhcc10116	rigid:OaXQ9NA25fwCWxejPU3Ao9q5j/E	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q5XIE8	uniprotkb:Q64119	intact:EBI-15348306|ensembl:ENSRNOP00000023037	intact:EBI-26437750	psi-mi:itm2b_rat(display_long)|uniprotkb:Itm2b(gene name)|psi-mi:Itm2b(display_short)|uniprotkb:Immature BRI2(gene name synonym)|uniprotkb:Transmembrane protein BRI(gene name synonym)	psi-mi:myl6_rat(display_long)|uniprotkb:Myl6(gene name)|psi-mi:Myl6(display_short)|uniprotkb:17 kDa myosin light chain(gene name synonym)|uniprotkb:Myosin light chain 3(gene name synonym)|uniprotkb:Myosin light chain alkali 3(gene name synonym)|uniprotkb:Smooth muscle and nonmuscle myosin light chain alkali 6(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Martins et al. (2018)	imex:IM-28469|pubmed:29476059	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26438079|imex:IM-28469-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSRNOG00000016271(gene)|ensembl:ENSRNOT00000023037(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001540"(amyloid-beta binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0010008"(endosome membrane)|go:"GO:0030660"(Golgi-associated vesicle membrane)|go:"GO:0031301"(integral component of organelle membrane)|go:"GO:0042985"(negative regulation of amyloid precursor protein biosynthetic process)|interpro:IPR007084(BRICHOS)|interpro:IPR040145|mint:Q5XIE8|refseq:NP_001006964.1|rgd:620727	go:"GO:0000146"(microfilament motor activity)|go:"GO:0003774"(cytoskeletal motor activity)|go:"GO:0005509"(calcium ion binding)|go:"GO:0006936"(muscle contraction)|go:"GO:0007519"(skeletal muscle tissue development)|go:"GO:0008307"(structural constituent of muscle)|go:"GO:0016459"(myosin complex)|go:"GO:0016461"(unconventional myosin complex)|go:"GO:0030049"(muscle filament sliding)|mint:Q64119|refseq:NP_001094453.1|interpro:IPR011992(EF-Hand type)|interpro:IPR002048(Calcium-binding EF-hand)|rgd:1305620	-	-	-	figure legend:ST1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10116(rat-brain-cerebellum)|taxid:10116(Rattus norvegicus)	-	2020/10/30	2020/10/30	rogid:DtE+ZXAZKdCMvUW5K+jXQ5bH07M10116	rogid:7L1ZyEG5CDK89dn56Tvy1TZlSPc10116	rigid:OaXQ9NA25fwCWxejPU3Ao9q5j/E	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q5XIE8	uniprotkb:Q63560	intact:EBI-15348306|ensembl:ENSRNOP00000023037	intact:EBI-1638469|uniprotkb:O88748|uniprotkb:Q6AYX8	psi-mi:itm2b_rat(display_long)|uniprotkb:Itm2b(gene name)|psi-mi:Itm2b(display_short)|uniprotkb:Immature BRI2(gene name synonym)|uniprotkb:Transmembrane protein BRI(gene name synonym)	psi-mi:map6_rat(display_long)|uniprotkb:Map6(gene name)|psi-mi:Map6(display_short)|uniprotkb:Mtap6(gene name synonym)|uniprotkb:Stable tubule-only polypeptide(gene name synonym)|uniprotkb:145-kDa STOP(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Martins et al. (2018)	imex:IM-28469|pubmed:29476059	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26438079|imex:IM-28469-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSRNOG00000016271(gene)|ensembl:ENSRNOT00000023037(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001540"(amyloid-beta binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0010008"(endosome membrane)|go:"GO:0030660"(Golgi-associated vesicle membrane)|go:"GO:0031301"(integral component of organelle membrane)|go:"GO:0042985"(negative regulation of amyloid precursor protein biosynthetic process)|interpro:IPR007084(BRICHOS)|interpro:IPR040145|mint:Q5XIE8|refseq:NP_001006964.1|rgd:620727	interpro:IPR007882(STOP)|rgd:61804|refseq:NP_058900.1|mint:Q63560|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005798"(Golgi-associated vesicle)|go:"GO:0005801"(cis-Golgi network)|go:"GO:0005874"(microtubule)|go:"GO:0008017"(microtubule binding)|go:"GO:0019896"(axonal transport of mitochondrion)|go:"GO:0030424"(axon)|go:"GO:0030425"(dendrite)|go:"GO:0030658"(transport vesicle membrane)|go:"GO:0030705"(cytoskeleton-dependent intracellular transport)|go:"GO:0032418"(lysosome localization)|go:"GO:0043005"(neuron projection)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0048813"(dendrite morphogenesis)|go:"GO:0050772"(positive regulation of axonogenesis)|go:"GO:0070507"(regulation of microtubule cytoskeleton organization)|go:"GO:0099503"(secretory vesicle)|go:"GO:1904115"(axon cytoplasm)	-	-	-	figure legend:ST1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10116(rat-brain-cerebellum)|taxid:10116(Rattus norvegicus)	-	2020/10/30	2020/10/30	rogid:DtE+ZXAZKdCMvUW5K+jXQ5bH07M10116	rogid:lWnLN3HrXruyxTIYdSN5wtDmea010116	rigid:OaXQ9NA25fwCWxejPU3Ao9q5j/E	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q5XIE8	uniprotkb:P15205	intact:EBI-15348306|ensembl:ENSRNOP00000023037	intact:EBI-349666|uniprotkb:Q62958|uniprotkb:Q9ER21|uniprotkb:Q9QW92|ensembl:ENSRNOP00000023460|uniprotkb:B0BNK3|uniprotkb:F1LRL9	psi-mi:itm2b_rat(display_long)|uniprotkb:Itm2b(gene name)|psi-mi:Itm2b(display_short)|uniprotkb:Immature BRI2(gene name synonym)|uniprotkb:Transmembrane protein BRI(gene name synonym)	psi-mi:map1b_rat(display_long)|uniprotkb:Map1b(gene name)|psi-mi:Map1b(display_short)|uniprotkb:Neuraxin(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Martins et al. (2018)	imex:IM-28469|pubmed:29476059	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26438079|imex:IM-28469-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSRNOG00000016271(gene)|ensembl:ENSRNOT00000023037(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001540"(amyloid-beta binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0010008"(endosome membrane)|go:"GO:0030660"(Golgi-associated vesicle membrane)|go:"GO:0031301"(integral component of organelle membrane)|go:"GO:0042985"(negative regulation of amyloid precursor protein biosynthetic process)|interpro:IPR007084(BRICHOS)|interpro:IPR040145|mint:Q5XIE8|refseq:NP_001006964.1|rgd:620727	rgd:3043|refseq:NP_062090.1|ensembl:ENSRNOG00000017428(gene)|ensembl:ENSRNOT00000023460(transcript)|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0001578"(microtubule bundle formation)|go:"GO:0001750"(photoreceptor outer segment)|go:"GO:0003779"(actin binding)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005874"(microtubule)|go:"GO:0005875"(microtubule associated complex)|go:"GO:0005886"(plasma membrane)|go:"GO:0007026"(negative regulation of microtubule depolymerization)|go:"GO:0007399"(nervous system development)|go:"GO:0007409"(axonogenesis)|go:"GO:0007416"(synapse assembly)|go:"GO:0008017"(microtubule binding)|go:"GO:0009611"(response to wounding)|go:"GO:0009612"(response to mechanical stimulus)|go:"GO:0009743"(response to carbohydrate)|go:"GO:0009987"(cellular process)|go:"GO:0010035"(response to inorganic substance)|go:"GO:0014012"(peripheral nervous system axon regeneration)|go:"GO:0014069"(postsynaptic density)|go:"GO:0016358"(dendrite development)|go:"GO:0017085"(response to insecticide)|go:"GO:0005543"(phospholipid binding)|go:"GO:0048675"(axon extension)|go:"GO:0048678"(response to axon injury)|go:"GO:0051915"(induction of synaptic plasticity by chemical substance)|go:"GO:0061162"(establishment of monopolar cell polarity)|go:"GO:0071363"(cellular response to growth factor stimulus)|go:"GO:0071375"(cellular response to peptide hormone stimulus)|go:"GO:0097440"(apical dendrite)|go:"GO:0097441"(basal dendrite)|go:"GO:0097457"(hippocampal mossy fiber)|interpro:IPR000102(Neuraxin/MAP1B repeat)|interpro:IPR026074|interpro:IPR027321|mint:P15205|go:"GO:0030424"(axon)|go:"GO:0030425"(dendrite)|go:"GO:0030426"(growth cone)|go:"GO:0031114"(regulation of microtubule depolymerization)|go:"GO:0021700"(developmental maturation)|go:"GO:0031116"(positive regulation of microtubule polymerization)|go:"GO:0031667"(response to nutrient levels)|go:"GO:0032355"(response to estradiol)|go:"GO:0032387"(negative regulation of intracellular transport)|go:"GO:0033189"(response to vitamin A)|go:"GO:0036477"(somatodendritic compartment)|go:"GO:0042493"|go:"GO:0043025"(neuronal cell body)|go:"GO:0043196"(varicosity)|go:"GO:0043197"(dendritic spine)|go:"GO:0043204"(perikaryon)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045202"(synapse)|go:"GO:0045666"(positive regulation of neuron differentiation)|go:"GO:0045773"(positive regulation of axon extension)|go:"GO:0047497"(mitochondrion transport along microtubule)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0048666"(neuron development)	-	-	-	figure legend:ST1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10116(rat-brain-cerebellum)|taxid:10116(Rattus norvegicus)	-	2020/10/30	2020/10/30	rogid:DtE+ZXAZKdCMvUW5K+jXQ5bH07M10116	rogid:ymryqrEfxWtJQiPb6jgYe8bzDX410116	rigid:OaXQ9NA25fwCWxejPU3Ao9q5j/E	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q5XIE8	uniprotkb:Q3KR86	intact:EBI-15348306|ensembl:ENSRNOP00000023037	intact:EBI-16220282	psi-mi:itm2b_rat(display_long)|uniprotkb:Itm2b(gene name)|psi-mi:Itm2b(display_short)|uniprotkb:Immature BRI2(gene name synonym)|uniprotkb:Transmembrane protein BRI(gene name synonym)	psi-mi:mic60_rat(display_long)|uniprotkb:Immt(gene name)|psi-mi:Immt(display_short)|uniprotkb:Mic60(gene name synonym)|uniprotkb:Mitochondrial inner membrane protein(gene name synonym)|uniprotkb:Mitofilin(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Martins et al. (2018)	imex:IM-28469|pubmed:29476059	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26438079|imex:IM-28469-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSRNOG00000016271(gene)|ensembl:ENSRNOT00000023037(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001540"(amyloid-beta binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0010008"(endosome membrane)|go:"GO:0030660"(Golgi-associated vesicle membrane)|go:"GO:0031301"(integral component of organelle membrane)|go:"GO:0042985"(negative regulation of amyloid precursor protein biosynthetic process)|interpro:IPR007084(BRICHOS)|interpro:IPR040145|mint:Q5XIE8|refseq:NP_001006964.1|rgd:620727	go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005758"(mitochondrial intermembrane space)|go:"GO:0009409"(response to cold)|go:"GO:0042407"(cristae formation)|go:"GO:0051560"(mitochondrial calcium ion homeostasis)|go:"GO:0061617"(MICOS complex)|mint:Q3KR86|rgd:1310684|refseq:NP_001030100.1|interpro:IPR019133	-	-	-	figure legend:ST1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10116(rat-brain-cerebellum)|taxid:10116(Rattus norvegicus)	-	2020/10/30	2020/10/30	rogid:DtE+ZXAZKdCMvUW5K+jXQ5bH07M10116	rogid:8w7k7GqkoWnY0fLU70i0ItueVVI10116	rigid:OaXQ9NA25fwCWxejPU3Ao9q5j/E	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q5XIE8	uniprotkb:Q2PQA9	intact:EBI-15348306|ensembl:ENSRNOP00000023037	intact:EBI-920191|uniprotkb:Q9WV65|ensembl:ENSRNOP00000023860	psi-mi:itm2b_rat(display_long)|uniprotkb:Itm2b(gene name)|psi-mi:Itm2b(display_short)|uniprotkb:Immature BRI2(gene name synonym)|uniprotkb:Transmembrane protein BRI(gene name synonym)	psi-mi:kinh_rat(display_long)|uniprotkb:Kif5b(gene name)|psi-mi:Kif5b(display_short)|uniprotkb:Ubiquitous kinesin heavy chain(gene name synonym)|uniprotkb:Conventional kinesin heavy chain(gene name synonym)|uniprotkb:Khc(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Martins et al. (2018)	imex:IM-28469|pubmed:29476059	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26438079|imex:IM-28469-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSRNOG00000016271(gene)|ensembl:ENSRNOT00000023037(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001540"(amyloid-beta binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0010008"(endosome membrane)|go:"GO:0030660"(Golgi-associated vesicle membrane)|go:"GO:0031301"(integral component of organelle membrane)|go:"GO:0042985"(negative regulation of amyloid precursor protein biosynthetic process)|interpro:IPR007084(BRICHOS)|interpro:IPR040145|mint:Q5XIE8|refseq:NP_001006964.1|rgd:620727	rgd:621559|refseq:NP_476550.1|refseq:XP_006254067.1|ensembl:ENSRNOG00000017466(gene)|ensembl:ENSRNOT00000023861(transcript)|go:"GO:0003777"(microtubule motor activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005829"(cytosol)|go:"GO:0005871"(kinesin complex)|go:"GO:0005874"(microtubule)|go:"GO:0007018"(microtubule-based movement)|go:"GO:0007028"(cytoplasm organization)|go:"GO:0007411"(axon guidance)|go:"GO:0007420"(brain development)|go:"GO:0008017"(microtubule binding)|go:"GO:0008432"(JUN kinase binding)|go:"GO:0008574"(plus-end-directed microtubule motor activity)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0021766"(hippocampus development)|go:"GO:0030139"(endocytic vesicle)|go:"GO:0030705"(cytoskeleton-dependent intracellular transport)|go:"GO:0031340"(positive regulation of vesicle fusion)|go:"GO:0031982"(vesicle)|go:"GO:0032230"(positive regulation of synaptic transmission, GABAergic)|go:"GO:0032418"(lysosome localization)|go:"GO:0032839"(dendrite cytoplasm)|go:"GO:0034451"(centriolar satellite)|go:"GO:0035253"(ciliary rootlet)|go:"GO:0035617"(stress granule disassembly)|go:"GO:0035774"(positive regulation of insulin secretion involved in cellular response to glucose stimulus)|go:"GO:0042267"(natural killer cell mediated cytotoxicity)|go:"GO:0042391"(regulation of membrane potential)|go:"GO:0042802"(identical protein binding)|go:"GO:0043005"(neuron projection)|go:"GO:0043227"(membrane-bounded organelle)|go:"GO:0043268"(positive regulation of potassium ion transport)|go:"GO:0044295"(axonal growth cone)|go:"GO:0045335"(phagocytic vesicle)|go:"GO:0047496"(vesicle transport along microtubule)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0048489"(synaptic vesicle transport)|go:"GO:0051642"(centrosome localization)|go:"GO:0071346"(cellular response to interferon-gamma)|go:"GO:0072383"(plus-end-directed vesicle transport along microtubule)|go:"GO:0090316"(positive regulation of intracellular protein transport)|go:"GO:0098971"(anterograde dendritic transport of neurotransmitter receptor complex)|go:"GO:0099609"(microtubule lateral binding)|go:"GO:0099641"(anterograde axonal protein transport)|go:"GO:1903078"(positive regulation of protein localization to plasma membrane)|go:"GO:1904115"(axon cytoplasm)|go:"GO:1905152"(positive regulation of voltage-gated sodium channel activity)|go:"GO:1990049"(retrograde neuronal dense core vesicle transport)|interpro:IPR001752(Kinesin, motor region)|interpro:IPR019821|interpro:IPR027417|interpro:IPR027640|interpro:IPR036961|mint:Q2PQA9|rcsb pdb:4ATX|reactome:R-RNO-2132295|reactome:R-RNO-5625970|reactome:R-RNO-6811434|reactome:R-RNO-983189|dip:DIP-37054N	-	-	-	figure legend:ST1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10116(rat-brain-cerebellum)|taxid:10116(Rattus norvegicus)	-	2020/10/30	2020/10/30	rogid:DtE+ZXAZKdCMvUW5K+jXQ5bH07M10116	rogid:OjHE/OLj2diwiW5HI0HFHEDkbjY10116	rigid:OaXQ9NA25fwCWxejPU3Ao9q5j/E	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q5XIE8	uniprotkb:P37285	intact:EBI-15348306|ensembl:ENSRNOP00000023037	intact:EBI-917396|ensembl:ENSRNOP00000075931	psi-mi:itm2b_rat(display_long)|uniprotkb:Itm2b(gene name)|psi-mi:Itm2b(display_short)|uniprotkb:Immature BRI2(gene name synonym)|uniprotkb:Transmembrane protein BRI(gene name synonym)	psi-mi:klc1_rat(display_long)|uniprotkb:Klc1(gene name)|psi-mi:Klc1(display_short)|uniprotkb:Klc(gene name synonym)|uniprotkb:Kns2(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Martins et al. (2018)	imex:IM-28469|pubmed:29476059	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26438079|imex:IM-28469-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSRNOG00000016271(gene)|ensembl:ENSRNOT00000023037(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001540"(amyloid-beta binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0010008"(endosome membrane)|go:"GO:0030660"(Golgi-associated vesicle membrane)|go:"GO:0031301"(integral component of organelle membrane)|go:"GO:0042985"(negative regulation of amyloid precursor protein biosynthetic process)|interpro:IPR007084(BRICHOS)|interpro:IPR040145|mint:Q5XIE8|refseq:NP_001006964.1|rgd:620727	rgd:621411|refseq:NP_001075442.1|refseq:NP_001075443.1|dip:DIP-36927N|ensembl:ENSRNOG00000011572(gene)|ensembl:ENSRNOT00000092774(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005871"(kinesin complex)|go:"GO:0005874"(microtubule)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0008088"(axo-dendritic transport)|go:"GO:0015631"(tubulin binding)|go:"GO:0016020"(membrane)|go:"GO:0030424"(axon)|go:"GO:0030426"(growth cone)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0031982"(vesicle)|go:"GO:0035253"(ciliary rootlet)|go:"GO:0035418"(protein localization to synapse)|go:"GO:0035617"(stress granule disassembly)|go:"GO:0043005"(neuron projection)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043227"(membrane-bounded organelle)|interpro:IPR002151(Kinesin light chain)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR015792(Kinesin light chain repeat)|interpro:IPR019734|mint:P37285|reactome:R-RNO-2132295|reactome:R-RNO-5625970|reactome:R-RNO-6811434|reactome:R-RNO-983189	-	-	-	figure legend:ST1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10116(rat-brain-cerebellum)|taxid:10116(Rattus norvegicus)	-	2020/10/30	2020/10/30	rogid:DtE+ZXAZKdCMvUW5K+jXQ5bH07M10116	rogid:4o3poOHtmPnoLq/XTguA0Z1P14o10116	rigid:OaXQ9NA25fwCWxejPU3Ao9q5j/E	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q5XIE8	uniprotkb:Q63617	intact:EBI-15348306|ensembl:ENSRNOP00000023037	intact:EBI-8761989	psi-mi:itm2b_rat(display_long)|uniprotkb:Itm2b(gene name)|psi-mi:Itm2b(display_short)|uniprotkb:Immature BRI2(gene name synonym)|uniprotkb:Transmembrane protein BRI(gene name synonym)	psi-mi:hyou1_rat(display_long)|uniprotkb:Hyou1(gene name)|psi-mi:Hyou1(display_short)|uniprotkb:Orp150(gene name synonym)|uniprotkb:150 kDa oxygen-regulated protein(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Martins et al. (2018)	imex:IM-28469|pubmed:29476059	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26438079|imex:IM-28469-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSRNOG00000016271(gene)|ensembl:ENSRNOT00000023037(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001540"(amyloid-beta binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0010008"(endosome membrane)|go:"GO:0030660"(Golgi-associated vesicle membrane)|go:"GO:0031301"(integral component of organelle membrane)|go:"GO:0042985"(negative regulation of amyloid precursor protein biosynthetic process)|interpro:IPR007084(BRICHOS)|interpro:IPR040145|mint:Q5XIE8|refseq:NP_001006964.1|rgd:620727	mint:Q63617|interpro:IPR018181|interpro:IPR013126(Heat shock protein 70)|refseq:NP_620222.2|rgd:621146|interpro:IPR029047|interpro:IPR029048|go:"GO:0001666"(response to hypoxia)|go:"GO:0002931"(response to ischemia)|go:"GO:0005524"(ATP binding)|go:"GO:0005788"(endoplasmic reticulum lumen)|go:"GO:0005790"(smooth endoplasmic reticulum)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0034663"(endoplasmic reticulum chaperone complex)|go:"GO:0034976"(response to endoplasmic reticulum stress)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0071456"(cellular response to hypoxia)|go:"GO:1903298"(negative regulation of hypoxia-induced intrinsic apoptotic signaling pathway)|go:"GO:1903382"(negative regulation of endoplasmic reticulum stress-induced neuron intrinsic apoptotic signaling pathway)|interpro:IPR043129	-	-	-	figure legend:ST1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10116(rat-brain-cerebellum)|taxid:10116(Rattus norvegicus)	-	2020/10/30	2020/10/30	rogid:DtE+ZXAZKdCMvUW5K+jXQ5bH07M10116	rogid:a64+yExj4exM2hN2NiQHoMi/Y4A10116	rigid:OaXQ9NA25fwCWxejPU3Ao9q5j/E	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q5XIE8	uniprotkb:P62804	intact:EBI-15348306|ensembl:ENSRNOP00000023037	intact:EBI-16220020|ensembl:ENSRNOP00000039602|ensembl:ENSRNOP00000066622|ensembl:ENSRNOP00000066653|ensembl:ENSRNOP00000066695|ensembl:ENSRNOP00000067176|ensembl:ENSRNOP00000067502|ensembl:ENSRNOP00000067813|ensembl:ENSRNOP00000069989|ensembl:ENSRNOP00000071163|ensembl:ENSRNOP00000074659|ensembl:ENSRNOP00000074796|ensembl:ENSRNOP00000065233|uniprotkb:P02304|uniprotkb:P02305|uniprotkb:Q5BM23|uniprotkb:Q7M0E8	psi-mi:itm2b_rat(display_long)|uniprotkb:Itm2b(gene name)|psi-mi:Itm2b(display_short)|uniprotkb:Immature BRI2(gene name synonym)|uniprotkb:Transmembrane protein BRI(gene name synonym)	psi-mi:h4_rat(display_long)|uniprotkb:H4c2(gene name)|psi-mi:H4c2(display_short)|uniprotkb:H4f16(gene name)|psi-mi:H4f16(display_short)|uniprotkb:Hist4h4(gene name synonym)|uniprotkb:Hist1h4b(gene name synonym)|uniprotkb:Hist4(gene name synonym)|uniprotkb:Hist1h4m(gene name)|psi-mi:Hist1h4m(display_short)|uniprotkb:H4ft(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Martins et al. (2018)	imex:IM-28469|pubmed:29476059	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26438079|imex:IM-28469-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSRNOG00000016271(gene)|ensembl:ENSRNOT00000023037(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001540"(amyloid-beta binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0010008"(endosome membrane)|go:"GO:0030660"(Golgi-associated vesicle membrane)|go:"GO:0031301"(integral component of organelle membrane)|go:"GO:0042985"(negative regulation of amyloid precursor protein biosynthetic process)|interpro:IPR007084(BRICHOS)|interpro:IPR040145|mint:Q5XIE8|refseq:NP_001006964.1|rgd:620727	ensembl:ENSRNOG00000032224(gene)|ensembl:ENSRNOG00000045840(gene)|ensembl:ENSRNOG00000045978(gene)|ensembl:ENSRNOG00000046636(gene)|ensembl:ENSRNOG00000048215(gene)|ensembl:ENSRNOG00000048642(gene)|ensembl:ENSRNOG00000048735(gene)|ensembl:ENSRNOG00000050933(gene)|ensembl:ENSRNOG00000051891(gene)|ensembl:ENSRNOG00000054017(gene)|ensembl:ENSRNOG00000057690(gene)|ensembl:ENSRNOG00000058444(gene)|ensembl:ENSRNOT00000040210(transcript)|ensembl:ENSRNOT00000071512(transcript)|ensembl:ENSRNOT00000072147(transcript)|ensembl:ENSRNOT00000072286(transcript)|ensembl:ENSRNOT00000074109(transcript)|ensembl:ENSRNOT00000074198(transcript)|ensembl:ENSRNOT00000074526(transcript)|ensembl:ENSRNOT00000075065(transcript)|ensembl:ENSRNOT00000080490(transcript)|ensembl:ENSRNOT00000085381(transcript)|ensembl:ENSRNOT00000088408(transcript)|ensembl:ENSRNOT00000091201(transcript)|go:"GO:0000228"(nuclear chromosome)|go:"GO:0000786"(nucleosome)|go:"GO:0001503"(ossification)|go:"GO:0003677"(DNA binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006334"(nucleosome assembly)|go:"GO:0006335"(DNA replication-dependent chromatin assembly)|go:"GO:0006336"(DNA replication-independent chromatin assembly)|go:"GO:0006352"(DNA-templated transcription, initiation)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030154"(cell differentiation)|go:"GO:0032991"(protein-containing complex)|go:"GO:0045653"(negative regulation of megakaryocyte differentiation)|go:"GO:0046982"(protein heterodimerization activity)|interpro:IPR001951(Histone H4)|interpro:IPR004823("TATA box binding protein associated factor (TAF)")|interpro:IPR009072(Histone-fold)|interpro:IPR019809|interpro:IPR035425|mint:P62804|reactome:R-RNO-110330|reactome:R-RNO-110331|reactome:R-RNO-171306|reactome:R-RNO-201722|reactome:R-RNO-212300|reactome:R-RNO-2299718|reactome:R-RNO-2559580|reactome:R-RNO-2559582|reactome:R-RNO-2559586|reactome:R-RNO-3214841|reactome:R-RNO-3214842|reactome:R-RNO-3214847|reactome:R-RNO-3214858|reactome:R-RNO-427359|reactome:R-RNO-427413|reactome:R-RNO-4551638|reactome:R-RNO-5250924|reactome:R-RNO-5578749|reactome:R-RNO-5625886|reactome:R-RNO-5693565|reactome:R-RNO-5693571|reactome:R-RNO-5693607|reactome:R-RNO-606279|reactome:R-RNO-69473|reactome:R-RNO-73728|reactome:R-RNO-73772|reactome:R-RNO-8936459|reactome:R-RNO-9018519|reactome:R-RNO-9670095|rgd:620814|refseq:NP_001116941.1|refseq:NP_001258150.1|refseq:NP_073177.1|refseq:XP_003749904.3|refseq:XP_008761668.1|refseq:XP_008761670.1|refseq:XP_008769992.1|refseq:XP_008772221.1|refseq:XP_578415.4	-	-	-	figure legend:ST1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10116(rat-brain-cerebellum)|taxid:10116(Rattus norvegicus)	-	2020/10/30	2020/10/30	rogid:DtE+ZXAZKdCMvUW5K+jXQ5bH07M10116	rogid:LZSfhrpw0PcDREEoJ1UMkBvnUfA10116	rigid:OaXQ9NA25fwCWxejPU3Ao9q5j/E	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q5XIE8	uniprotkb:Q00715	intact:EBI-15348306|ensembl:ENSRNOP00000023037	intact:EBI-931728	psi-mi:itm2b_rat(display_long)|uniprotkb:Itm2b(gene name)|psi-mi:Itm2b(display_short)|uniprotkb:Immature BRI2(gene name synonym)|uniprotkb:Transmembrane protein BRI(gene name synonym)	psi-mi:h2b1_rat(display_long)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Martins et al. (2018)	imex:IM-28469|pubmed:29476059	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26438079|imex:IM-28469-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSRNOG00000016271(gene)|ensembl:ENSRNOT00000023037(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001540"(amyloid-beta binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0010008"(endosome membrane)|go:"GO:0030660"(Golgi-associated vesicle membrane)|go:"GO:0031301"(integral component of organelle membrane)|go:"GO:0042985"(negative regulation of amyloid precursor protein biosynthetic process)|interpro:IPR007084(BRICHOS)|interpro:IPR040145|mint:Q5XIE8|refseq:NP_001006964.1|rgd:620727	refseq:NP_072173.1|interpro:IPR009072(Histone-fold)|interpro:IPR007125(Histone core)|interpro:IPR000558(Histone H2B)|mint:Q00715|go:"GO:0000786"(nucleosome)|go:"GO:0003677"(DNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006334"(nucleosome assembly)|go:"GO:0042742"(defense response to bacterium)|go:"GO:0046982"(protein heterodimerization activity)	-	-	-	figure legend:ST1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10116(rat-brain-cerebellum)|taxid:10116(Rattus norvegicus)	-	2020/10/30	2020/10/30	rogid:DtE+ZXAZKdCMvUW5K+jXQ5bH07M10116	rogid:MmU330IlxzGgIpswI5joy179agY10116	rigid:OaXQ9NA25fwCWxejPU3Ao9q5j/E	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q5XIE8	uniprotkb:P34058	intact:EBI-15348306|ensembl:ENSRNOP00000023037	intact:EBI-917279|uniprotkb:Q1PSW2|uniprotkb:Q66H55|uniprotkb:Q68GV5|uniprotkb:Q9QWC6|ensembl:ENSRNOP00000026920	psi-mi:itm2b_rat(display_long)|uniprotkb:Itm2b(gene name)|psi-mi:Itm2b(display_short)|uniprotkb:Immature BRI2(gene name synonym)|uniprotkb:Transmembrane protein BRI(gene name synonym)	psi-mi:hs90b_rat(display_long)|uniprotkb:Heat shock 84 kDa(gene name synonym)|uniprotkb:Hsp90ab1(gene name)|psi-mi:Hsp90ab1(display_short)|uniprotkb:Hsp84(gene name synonym)|uniprotkb:Hspcb(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Martins et al. (2018)	imex:IM-28469|pubmed:29476059	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26438079|imex:IM-28469-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSRNOG00000016271(gene)|ensembl:ENSRNOT00000023037(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001540"(amyloid-beta binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0010008"(endosome membrane)|go:"GO:0030660"(Golgi-associated vesicle membrane)|go:"GO:0031301"(integral component of organelle membrane)|go:"GO:0042985"(negative regulation of amyloid precursor protein biosynthetic process)|interpro:IPR007084(BRICHOS)|interpro:IPR040145|mint:Q5XIE8|refseq:NP_001006964.1|rgd:620727	rgd:1303075|refseq:NP_001004082.3|ensembl:ENSRNOG00000019834(gene)|ensembl:ENSRNOT00000026920(transcript)|go:"GO:0001890"(placenta development)|go:"GO:0002134"(UTP binding)|go:"GO:0002135"(CTP binding)|go:"GO:0003725"(double-stranded RNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005525"(GTP binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006457"(protein folding)|go:"GO:0006986"(response to unfolded protein)|go:"GO:0007004"(telomere maintenance via telomerase)|go:"GO:0008180"(COP9 signalosome)|go:"GO:0009651"(response to salt stress)|go:"GO:0009986"(cell surface)|go:"GO:0010033"(response to organic substance)|go:"GO:0016234"(inclusion body)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0017098"(sulfonylurea receptor binding)|go:"GO:0019062"(virion attachment to host cell)|go:"GO:0019887"(protein kinase regulator activity)|go:"GO:0019900"(kinase binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0021955"(central nervous system neuron axonogenesis)|go:"GO:0030010"(establishment of cell polarity)|go:"GO:0030511"(positive regulation of transforming growth factor beta receptor signaling pathway)|go:"GO:0031072"(heat shock protein binding)|go:"GO:0031396"(regulation of protein ubiquitination)|go:"GO:0031526"(brush border membrane)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032092"(positive regulation of protein binding)|go:"GO:0032435"(negative regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0032516"(positive regulation of phosphoprotein phosphatase activity)|go:"GO:0032564"(dATP binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033138"(positive regulation of peptidyl-serine phosphorylation)|go:"GO:0034605"(cellular response to heat)|go:"GO:0034751"(aryl hydrocarbon receptor complex)|go:"GO:0042220"(response to cocaine)|go:"GO:0042277"(peptide binding)|go:"GO:0042307"(positive regulation of protein import into nucleus)|go:"GO:0042470"(melanosome)|go:"GO:0042493"|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0043008"(ATP-dependent protein binding)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043202"(lysosomal lumen)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0044183"(protein folding chaperone)|go:"GO:0044294"(dendritic growth cone)|go:"GO:0044295"(axonal growth cone)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0045597"(positive regulation of cell differentiation)|go:"GO:0045793"(positive regulation of cell size)|go:"GO:0046983"(protein dimerization activity)|go:"GO:0048156"(tau protein binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0048675"(axon extension)|go:"GO:0050821"(protein stabilization)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0051131"(chaperone-mediated protein complex assembly)|go:"GO:0051248"(negative regulation of protein metabolic process)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0051897"(positive regulation of protein kinase B signaling)|go:"GO:0051973"(positive regulation of telomerase activity)|go:"GO:0060334"(regulation of interferon-gamma-mediated signaling pathway)|go:"GO:0060338"(regulation of type I interferon-mediated signaling pathway)|go:"GO:0061635"(regulation of protein complex stability)|go:"GO:0061684"(chaperone-mediated autophagy)|go:"GO:0070182"(DNA polymerase binding)|go:"GO:0071353"(cellular response to interleukin-4)|go:"GO:0071407"(cellular response to organic cyclic compound)|go:"GO:0071902"(positive regulation of protein serine/threonine kinase activity)|go:"GO:0097435"(supramolecular fiber organization)|go:"GO:0097718"(disordered domain specific binding)|go:"GO:0120293"(dynein axonemal particle)|go:"GO:0140597"(protein carrier chaperone)|go:"GO:1901389"(negative regulation of transforming growth factor beta activation)|go:"GO:1901799"(negative regulation of proteasomal protein catabolic process)|go:"GO:1903660"(negative regulation of complement-dependent cytotoxicity)|go:"GO:1903827"|go:"GO:1904031"(positive regulation of cyclin-dependent protein kinase activity)|go:"GO:1905323"(telomerase holoenzyme complex assembly)|go:"GO:1990226"(histone methyltransferase binding)|go:"GO:1990565"(HSP90-CDC37 chaperone complex)|go:"GO:1990913"(sperm head plasma membrane)|go:"GO:1990917"(ooplasm)|go:"GO:2000010"(positive regulation of protein localization to cell surface)|interpro:IPR001404(Heat shock protein Hsp90)|interpro:IPR003594(ATP-binding region, ATPase-like)|interpro:IPR019805|interpro:IPR020568|interpro:IPR020575|interpro:IPR036890|interpro:IPR037196|mint:P34058|reactome:R-RNO-168928|reactome:R-RNO-2029482|reactome:R-RNO-3371497|reactome:R-RNO-3371511|reactome:R-RNO-3371568|reactome:R-RNO-3371571|reactome:R-RNO-399954|reactome:R-RNO-6798695|reactome:R-RNO-844456|reactome:R-RNO-8852276|reactome:R-RNO-8937144|reactome:R-RNO-8939211|reactome:R-RNO-9013418|reactome:R-RNO-9018519	-	-	-	figure legend:ST1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10116(rat-brain-cerebellum)|taxid:10116(Rattus norvegicus)	-	2020/10/30	2020/10/30	rogid:DtE+ZXAZKdCMvUW5K+jXQ5bH07M10116	rogid:5/MXDESVXdwuWna0s87Ap19aLMA10116	rigid:OaXQ9NA25fwCWxejPU3Ao9q5j/E	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q5XIE8	uniprotkb:P82995	intact:EBI-15348306|ensembl:ENSRNOP00000023037	intact:EBI-919629|uniprotkb:Q91XW0|ensembl:ENSRNOP00000009556|ensembl:ENSRNOP00000075715	psi-mi:itm2b_rat(display_long)|uniprotkb:Itm2b(gene name)|psi-mi:Itm2b(display_short)|uniprotkb:Immature BRI2(gene name synonym)|uniprotkb:Transmembrane protein BRI(gene name synonym)	psi-mi:hs90a_rat(display_long)|uniprotkb:Hsp90aa1(gene name)|psi-mi:Hsp90aa1(display_short)|uniprotkb:Hspca(gene name synonym)|uniprotkb:Heat shock 86 kDa(gene name synonym)|uniprotkb:Hsp86(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Martins et al. (2018)	imex:IM-28469|pubmed:29476059	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26438079|imex:IM-28469-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSRNOG00000016271(gene)|ensembl:ENSRNOT00000023037(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001540"(amyloid-beta binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0010008"(endosome membrane)|go:"GO:0030660"(Golgi-associated vesicle membrane)|go:"GO:0031301"(integral component of organelle membrane)|go:"GO:0042985"(negative regulation of amyloid precursor protein biosynthetic process)|interpro:IPR007084(BRICHOS)|interpro:IPR040145|mint:Q5XIE8|refseq:NP_001006964.1|rgd:620727	refseq:XP_008763191.1|rgd:631409|refseq:NP_786937.1|ensembl:ENSRNOG00000007219(gene)|ensembl:ENSRNOG00000059714(gene)|ensembl:ENSRNOT00000009556(transcript)|ensembl:ENSRNOT00000086310(transcript)|go:"GO:0001764"(neuron migration)|go:"GO:0001934"(positive regulation of protein phosphorylation)|go:"GO:0002134"(UTP binding)|go:"GO:0002135"(CTP binding)|go:"GO:0002218"(activation of innate immune response)|go:"GO:0002230"(positive regulation of defense response to virus by host)|go:"GO:0003009"(skeletal muscle contraction)|go:"GO:0003729"(mRNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005525"(GTP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006457"(protein folding)|go:"GO:0007004"(telomere maintenance via telomerase)|go:"GO:0009408"(response to heat)|go:"GO:0009409"(response to cold)|go:"GO:0009651"(response to salt stress)|go:"GO:0009986"(cell surface)|go:"GO:0010592"(positive regulation of lamellipodium assembly)|go:"GO:0010659"(cardiac muscle cell apoptotic process)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0017098"(sulfonylurea receptor binding)|go:"GO:0019903"(protein phosphatase binding)|go:"GO:0021955"(central nervous system neuron axonogenesis)|go:"GO:0030010"(establishment of cell polarity)|go:"GO:0030235"(nitric-oxide synthase regulator activity)|go:"GO:0030911"(TPR domain binding)|go:"GO:0031396"(regulation of protein ubiquitination)|go:"GO:0031526"(brush border membrane)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032273"(positive regulation of protein polymerization)|go:"GO:0032564"(dATP binding)|go:"GO:0032728"(positive regulation of interferon-beta production)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033138"(positive regulation of peptidyl-serine phosphorylation)|go:"GO:0034605"(cellular response to heat)|go:"GO:0036126"(sperm flagellum)|go:"GO:0042220"(response to cocaine)|go:"GO:0042307"(positive regulation of protein import into nucleus)|go:"GO:0042470"(melanosome)|go:"GO:0042493"|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0043005"(neuron projection)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043202"(lysosomal lumen)|go:"GO:0043209"(myelin sheath)|go:"GO:0043627"(response to estrogen)|go:"GO:0044183"(protein folding chaperone)|go:"GO:0044294"(dendritic growth cone)|go:"GO:0044295"(axonal growth cone)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0045040"(protein insertion into mitochondrial outer membrane)|go:"GO:0045429"(positive regulation of nitric oxide biosynthetic process)|go:"GO:0045793"(positive regulation of cell size)|go:"GO:0046677"(response to antibiotic)|go:"GO:0048156"(tau protein binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0048675"(axon extension)|go:"GO:0050821"(protein stabilization)|go:"GO:0051020"(GTPase binding)|go:"GO:0051022"(Rho GDP-dissociation inhibitor binding)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0051131"(chaperone-mediated protein complex assembly)|go:"GO:0051897"(positive regulation of protein kinase B signaling)|go:"GO:0051973"(positive regulation of telomerase activity)|go:"GO:0060452"(positive regulation of cardiac muscle contraction)|go:"GO:0061635"(regulation of protein complex stability)|go:"GO:0061684"(chaperone-mediated autophagy)|go:"GO:0062023"(collagen-containing extracellular matrix)|go:"GO:0070182"(DNA polymerase binding)|go:"GO:0097110"(scaffold protein binding)|go:"GO:0097226"(sperm mitochondrial sheath)|go:"GO:0097524"(sperm plasma membrane)|go:"GO:0097718"(disordered domain specific binding)|go:"GO:0098586"(cellular response to virus)|go:"GO:0140597"(protein carrier chaperone)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|go:"GO:1902949"(positive regulation of tau-protein kinase activity)|go:"GO:1903364"(positive regulation of cellular protein catabolic process)|go:"GO:1903827"|go:"GO:1905323"(telomerase holoenzyme complex assembly)|go:"GO:1990782"(protein tyrosine kinase binding)|interpro:IPR001404(Heat shock protein Hsp90)|interpro:IPR003594(ATP-binding region, ATPase-like)|interpro:IPR019805|interpro:IPR020568|interpro:IPR020575|interpro:IPR036890|interpro:IPR037196|mint:P82995|reactome:R-RNO-1227986|reactome:R-RNO-1474151|reactome:R-RNO-168928|reactome:R-RNO-2029482|reactome:R-RNO-203615|reactome:R-RNO-2565942|reactome:R-RNO-3371497|reactome:R-RNO-3371511|reactome:R-RNO-3371568|reactome:R-RNO-3371571|reactome:R-RNO-380259|reactome:R-RNO-380270|reactome:R-RNO-380284|reactome:R-RNO-380320|reactome:R-RNO-399954|reactome:R-RNO-4420097|reactome:R-RNO-5218920|reactome:R-RNO-5620912|reactome:R-RNO-5675482|reactome:R-RNO-6798695|reactome:R-RNO-8852276|reactome:R-RNO-8854518|reactome:R-RNO-8863795|reactome:R-RNO-8939211|reactome:R-RNO-9009391|reactome:R-RNO-9013418|reactome:R-RNO-9018519|reactome:R-RNO-9652282	-	-	-	figure legend:ST1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10116(rat-brain-cerebellum)|taxid:10116(Rattus norvegicus)	-	2020/10/30	2020/10/30	rogid:DtE+ZXAZKdCMvUW5K+jXQ5bH07M10116	rogid:tqpvMNNqRR42cL/lpXrgcqJh0NE10116	rigid:OaXQ9NA25fwCWxejPU3Ao9q5j/E	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q5XIE8	uniprotkb:P09606	intact:EBI-15348306|ensembl:ENSRNOP00000023037	intact:EBI-349265|uniprotkb:Q6P7Q9|ensembl:ENSRNOP00000065890	psi-mi:itm2b_rat(display_long)|uniprotkb:Itm2b(gene name)|psi-mi:Itm2b(display_short)|uniprotkb:Immature BRI2(gene name synonym)|uniprotkb:Transmembrane protein BRI(gene name synonym)	psi-mi:glna_rat(display_long)|uniprotkb:Glns(gene name synonym)|uniprotkb:Glul(gene name)|psi-mi:Glul(display_short)|uniprotkb:Glutamate--ammonia ligase(gene name synonym)|uniprotkb:Palmitoyltransferase GLUL(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Martins et al. (2018)	imex:IM-28469|pubmed:29476059	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26438079|imex:IM-28469-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSRNOG00000016271(gene)|ensembl:ENSRNOT00000023037(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001540"(amyloid-beta binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0010008"(endosome membrane)|go:"GO:0030660"(Golgi-associated vesicle membrane)|go:"GO:0031301"(integral component of organelle membrane)|go:"GO:0042985"(negative regulation of amyloid precursor protein biosynthetic process)|interpro:IPR007084(BRICHOS)|interpro:IPR040145|mint:Q5XIE8|refseq:NP_001006964.1|rgd:620727	rgd:2710|refseq:NP_058769.4|ensembl:ENSRNOG00000049560(gene)|ensembl:ENSRNOT00000075480(transcript)|go:"GO:0000287"(magnesium ion binding)|go:"GO:0001525"(angiogenesis)|go:"GO:0004356"(glutamate-ammonia ligase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005791"(rough endoplasmic reticulum)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006536"(glutamate metabolic process)|go:"GO:0006542"(glutamine biosynthetic process)|go:"GO:0008283"(cell population proliferation)|go:"GO:0009267"(cellular response to starvation)|go:"GO:0009749"(response to glucose)|go:"GO:0010594"(regulation of endothelial cell migration)|go:"GO:0016595"(glutamate binding)|go:"GO:0018345"(protein palmitoylation)|go:"GO:0019676"(ammonia assimilation cycle)|go:"GO:0019706"(protein-cysteine S-palmitoyltransferase activity)|go:"GO:0030145"(manganese ion binding)|go:"GO:0032024"(positive regulation of insulin secretion)|go:"GO:0032991"(protein-containing complex)|go:"GO:0042133"(neurotransmitter metabolic process)|go:"GO:0042254"(ribosome biogenesis)|go:"GO:0042802"(identical protein binding)|go:"GO:0042995"(cell projection)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0043679"(axon terminus)|go:"GO:0044297"(cell body)|go:"GO:0045503"(dynein light chain binding)|go:"GO:0050679"(positive regulation of epithelial cell proliferation)|go:"GO:0051968"(positive regulation of synaptic transmission, glutamatergic)|go:"GO:0097386"(glial cell projection)|go:"GO:1903670"(regulation of sprouting angiogenesis)|go:"GO:1904749"(regulation of protein localization to nucleolus)|interpro:IPR008146(Glutamine synthetase, catalytic region)|interpro:IPR008147(Glutamine synthetase, beta-Grasp)|interpro:IPR014746(Glutamine synthetase/guanido kinase, catalytic region)|interpro:IPR027302|interpro:IPR027303|interpro:IPR036651|mint:P09606|go:"GO:0043005"(neuron projection)|reactome:R-RNO-210455|reactome:R-RNO-8964539|go:"GO:0043204"(perikaryon)|go:"GO:0043209"(myelin sheath)	-	-	-	figure legend:ST1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10116(rat-brain-cerebellum)|taxid:10116(Rattus norvegicus)	-	2020/10/30	2020/10/30	rogid:DtE+ZXAZKdCMvUW5K+jXQ5bH07M10116	rogid:VN1L4Kl9yF9dxmvXpA3f1prv0tw10116	rigid:OaXQ9NA25fwCWxejPU3Ao9q5j/E	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q5XIE8	uniprotkb:P19491	intact:EBI-15348306|ensembl:ENSRNOP00000023037	intact:EBI-77718|uniprotkb:Q9R174	psi-mi:itm2b_rat(display_long)|uniprotkb:Itm2b(gene name)|psi-mi:Itm2b(display_short)|uniprotkb:Immature BRI2(gene name synonym)|uniprotkb:Transmembrane protein BRI(gene name synonym)	psi-mi:gria2_rat(display_long)|uniprotkb:Gria2(gene name)|psi-mi:Gria2(display_short)|uniprotkb:Glur2(gene name synonym)|uniprotkb:GluR-B(gene name synonym)|uniprotkb:GluR-K2(gene name synonym)|uniprotkb:Glutamate receptor ionotropic, AMPA 2(gene name synonym)|uniprotkb:AMPA-selective glutamate receptor 2(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Martins et al. (2018)	imex:IM-28469|pubmed:29476059	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26438079|imex:IM-28469-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSRNOG00000016271(gene)|ensembl:ENSRNOT00000023037(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001540"(amyloid-beta binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0010008"(endosome membrane)|go:"GO:0030660"(Golgi-associated vesicle membrane)|go:"GO:0031301"(integral component of organelle membrane)|go:"GO:0042985"(negative regulation of amyloid precursor protein biosynthetic process)|interpro:IPR007084(BRICHOS)|interpro:IPR040145|mint:Q5XIE8|refseq:NP_001006964.1|rgd:620727	go:"GO:0019901"(protein kinase binding)|go:"GO:0030165"(PDZ domain binding)|go:"GO:0030425"(dendrite)|go:"GO:0030426"(growth cone)|go:"GO:0030672"(synaptic vesicle membrane)|go:"GO:0031623"(receptor internalization)|go:"GO:0032279"(asymmetric synapse)|go:"GO:0032281"(AMPA glutamate receptor complex)|go:"GO:0032839"(dendrite cytoplasm)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035235"(ionotropic glutamate receptor signaling pathway)|go:"GO:0035254"(glutamate receptor binding)|go:"GO:0036477"(somatodendritic compartment)|go:"GO:0038023"(signaling receptor activity)|go:"GO:0042734"(presynaptic membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0043005"(neuron projection)|go:"GO:0043025"(neuronal cell body)|interpro:IPR028082|rcsb pdb:1FTJ|rcsb pdb:1FTK|rcsb pdb:1FTL|rcsb pdb:1FTM|rcsb pdb:1FTO|rcsb pdb:1FW0|rcsb pdb:1GR2|rcsb pdb:1LB8|rcsb pdb:1LB9|rcsb pdb:1LBB|rcsb pdb:1LBC|rcsb pdb:1M5B|rcsb pdb:1M5C|rcsb pdb:1M5D|rcsb pdb:1M5E|rcsb pdb:1M5F|rcsb pdb:1MM6|rcsb pdb:1MM7|rcsb pdb:1MQD|rcsb pdb:1MQG|rcsb pdb:1MQH|rcsb pdb:1MQI|rcsb pdb:1MQJ|rcsb pdb:1MS7|rcsb pdb:1MXU|rcsb pdb:1MXV|rcsb pdb:1MXW|rcsb pdb:1MXX|rcsb pdb:1MXY|rcsb pdb:1MXZ|rcsb pdb:1MY0|rcsb pdb:1MY1|rcsb pdb:1MY2|rcsb pdb:1MY3|go:"GO:0043195"(terminal bouton)|go:"GO:0043197"(dendritic spine)|go:"GO:0043198"(dendritic shaft)|go:"GO:0043204"(perikaryon)|go:"GO:0045184"(establishment of protein localization)|go:"GO:0045202"(synapse)|go:"GO:0045211"(postsynaptic membrane)|go:"GO:0050806"(positive regulation of synaptic transmission)|go:"GO:0051117"(ATPase binding)|go:"GO:0051262"(protein tetramerization)|go:"GO:0051966"(regulation of synaptic transmission, glutamatergic)|go:"GO:0060992"(response to fungicide)|go:"GO:0097060"(synaptic membrane)|go:"GO:0098685"(Schaffer collateral - CA1 synapse)|go:"GO:0098839"(postsynaptic density membrane)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099055"(integral component of postsynaptic membrane)|go:"GO:0099056"(integral component of presynaptic membrane)|go:"GO:0099061"(integral component of postsynaptic density membrane)|go:"GO:0099544"(perisynaptic space)|go:"GO:1904315"(transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential)|interpro:IPR001320(Ionotropic glutamate receptor)|interpro:IPR001508(NMDA receptor)|interpro:IPR001828(Extracellular ligand-binding receptor)|interpro:IPR019594|go:"GO:0001540"(amyloid-beta binding)|go:"GO:0001919"(regulation of receptor recycling)|go:"GO:0004970"(ionotropic glutamate receptor activity)|go:"GO:0004971"(AMPA glutamate receptor activity)|go:"GO:0000149"(SNARE binding)|go:"GO:0005234"(extracellularly glutamate-gated ion channel activity)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0007268"(chemical synaptic transmission)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0008092"(cytoskeletal protein binding)|go:"GO:0008328"(ionotropic glutamate receptor complex)|go:"GO:0009986"(cell surface)|go:"GO:0010226"(response to lithium ion)|go:"GO:0014069"(postsynaptic density)|go:"GO:0015276"(ligand-gated ion channel activity)|go:"GO:0015277"(kainate selective glutamate receptor activity)|go:"GO:0016020"(membrane)|go:"GO:0019865"(immunoglobulin binding)|rcsb pdb:1MY4|rcsb pdb:1N0T|rcsb pdb:1NNK|rcsb pdb:1NNP|rcsb pdb:1P1N|rcsb pdb:1P1O|rcsb pdb:1P1Q|rcsb pdb:1P1U|rcsb pdb:1P1W|rcsb pdb:1SYH|rcsb pdb:1SYI|rcsb pdb:1WVJ|rcsb pdb:1XHY|rcsb pdb:2AIX|rcsb pdb:2AL4|rcsb pdb:2AL5|rcsb pdb:2ANJ|rcsb pdb:2CMO|rcsb pdb:2GFE|rcsb pdb:2I3V|rcsb pdb:2I3W|rcsb pdb:2P2A|rcsb pdb:2UXA|rcsb pdb:2XX7|rcsb pdb:2XX8|rcsb pdb:2XX9|rcsb pdb:2XXH|rcsb pdb:2XXI|rcsb pdb:3B6Q|rcsb pdb:5NIH|rcsb pdb:5NS9|rcsb pdb:5O9A|rcsb pdb:5OEW|rcsb pdb:5VHW|rcsb pdb:5VHX|rcsb pdb:5VHY|rcsb pdb:5VHZ|rcsb pdb:5VOT|rcsb pdb:5VOU|rcsb pdb:5VOV|rcsb pdb:5WEK|rcsb pdb:5WEL|rcsb pdb:5WEM|rcsb pdb:5WEN|rcsb pdb:5WEO|rcsb pdb:6DLZ|rcsb pdb:6DM0|rcsb pdb:6DM1|rcsb pdb:6FAZ|rcsb pdb:6FQG|rcsb pdb:6FQH|rcsb pdb:6FQI|rcsb pdb:6FQJ|rcsb pdb:6FQK|rcsb pdb:6GIV|rcsb pdb:6GL4|rcsb pdb:6HC9|rcsb pdb:6HCA|rcsb pdb:6HCB|rcsb pdb:6HCC|rcsb pdb:6HCH|rcsb pdb:6NJL|rcsb pdb:6NJM|rcsb pdb:6NJN|rcsb pdb:6O9G|rcsb pdb:6PEQ|rcsb pdb:6Q54|rcsb pdb:6Q60|rcsb pdb:6QKC|rcsb pdb:6QKZ|rcsb pdb:3B6T|rcsb pdb:3B6W|rcsb pdb:3B7D|rcsb pdb:3BBR|rcsb pdb:3BFT|rcsb pdb:3BFU|rcsb pdb:3BKI|rcsb pdb:3DP6|rcsb pdb:3H03|rcsb pdb:3H06|rcsb pdb:3H5V|rcsb pdb:3H5W|rcsb pdb:3H6T|rcsb pdb:3H6U|rcsb pdb:3H6V|rcsb pdb:3H6W|rcsb pdb:3HSY|rcsb pdb:3IJO|rcsb pdb:3IJX|rcsb pdb:3IK6|rcsb pdb:3IL1|rcsb pdb:3ILT|rcsb pdb:3ILU|rcsb pdb:3KG2|rcsb pdb:3KGC|rcsb pdb:3LSF|rcsb pdb:3LSL|rcsb pdb:3M3L|rcsb pdb:3N6V|rcsb pdb:3O28|rcsb pdb:3O29|rcsb pdb:3O2A|rcsb pdb:3O2J|rcsb pdb:3O6G|rcsb pdb:3O6H|rcsb pdb:3O6I|rcsb pdb:3PD8|rcsb pdb:3PD9|rcsb pdb:3PMV|rcsb pdb:3PMW|rcsb pdb:3PMX|rcsb pdb:6RUQ|rcsb pdb:6U5S|rcsb pdb:6U6I|rcsb pdb:6UCB|rcsb pdb:6UD4|rcsb pdb:6UD8|rcsb pdb:6XSR|rcsb pdb:6YK2|rcsb pdb:6YK3|rcsb pdb:6YK4|rcsb pdb:6YK5|rcsb pdb:6YK6|rcsb pdb:7OCA|rcsb pdb:7OCC|rcsb pdb:7OCD|rcsb pdb:7OCE|rcsb pdb:7OCF|reactome:R-RNO-399710|reactome:R-RNO-416993|reactome:R-RNO-438066|rcsb pdb:3RTF|rcsb pdb:3RTW|rcsb pdb:3T93|rcsb pdb:3T96|rcsb pdb:3T9H|rcsb pdb:3T9U|rcsb pdb:3T9V|rcsb pdb:3T9X|rcsb pdb:3TDJ|rcsb pdb:3TKD|rcsb pdb:3TZA|rcsb pdb:4FAT|rcsb pdb:4G8M|rcsb pdb:4GXS|rcsb pdb:4H8J|rcsb pdb:4IGT|rcsb pdb:4ISU|rcsb pdb:4IY5|rcsb pdb:4IY6|rcsb pdb:4L17|rcsb pdb:4LZ5|rcsb pdb:4LZ7|rcsb pdb:4LZ8|rcsb pdb:4N07|rcsb pdb:4O3A|rcsb pdb:4O3B|rcsb pdb:4O3C|rcsb pdb:4Q30|rcsb pdb:4U1O|rcsb pdb:4U1W|rcsb pdb:4U1X|rcsb pdb:4U1Y|rcsb pdb:4U1Z|rcsb pdb:4U21|rcsb pdb:4U22|rcsb pdb:4U23|rcsb pdb:4U2P|rcsb pdb:4U2Q|rcsb pdb:4U2R|rcsb pdb:4U4F|rcsb pdb:4U4G|rcsb pdb:4U4S|rcsb pdb:4U4X|rcsb pdb:4U5B|rcsb pdb:4U5C|rcsb pdb:4U5D|rcsb pdb:4U5E|rcsb pdb:4U5F|rcsb pdb:4UQ6|rcsb pdb:4UQJ|rcsb pdb:4UQK|rcsb pdb:4X48|rcsb pdb:4YMA|rcsb pdb:4YU0|rcsb pdb:4Z0I|rcsb pdb:5BUU|rcsb pdb:5CBR|rcsb pdb:5CBS|rcsb pdb:5ELV|rcsb pdb:5FHM|rcsb pdb:5FHN|rcsb pdb:5FHO|rcsb pdb:5FTH|rcsb pdb:5FTI|rcsb pdb:5FWX|rcsb pdb:5FWY|rcsb pdb:5IDE|rcsb pdb:5IDF|rcsb pdb:5JEI|rcsb pdb:5KBS|rcsb pdb:5KBT|rcsb pdb:5KBU|rcsb pdb:5KBV|rcsb pdb:5KK2|rcsb pdb:5L1B|rcsb pdb:5L1E|rcsb pdb:5L1F|rcsb pdb:5L1G|rcsb pdb:5L1H|rcsb pdb:5N6P|rcsb pdb:5NG9|refseq:NP_001077280.1|refseq:NP_058957.1|rgd:61862|mint:P19491|dip:DIP-30952N	-	-	-	figure legend:ST1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10116(rat-brain-cerebellum)|taxid:10116(Rattus norvegicus)	-	2020/10/30	2020/10/30	rogid:DtE+ZXAZKdCMvUW5K+jXQ5bH07M10116	rogid:zeQRRvspsIuRyA9kKA7kyIr8HqE10116	rigid:OaXQ9NA25fwCWxejPU3Ao9q5j/E	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q5XIE8	uniprotkb:P47819	intact:EBI-15348306|ensembl:ENSRNOP00000023037	intact:EBI-931216|uniprotkb:Q7TQ31|uniprotkb:Q9R1Q3|uniprotkb:Q9Z2S0|uniprotkb:A7REI0|ensembl:ENSRNOP00000032389	psi-mi:itm2b_rat(display_long)|uniprotkb:Itm2b(gene name)|psi-mi:Itm2b(display_short)|uniprotkb:Immature BRI2(gene name synonym)|uniprotkb:Transmembrane protein BRI(gene name synonym)	psi-mi:gfap_rat(display_long)|uniprotkb:Gfap(gene name)|psi-mi:Gfap(display_short)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Martins et al. (2018)	imex:IM-28469|pubmed:29476059	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26438079|imex:IM-28469-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSRNOG00000016271(gene)|ensembl:ENSRNOT00000023037(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001540"(amyloid-beta binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0010008"(endosome membrane)|go:"GO:0030660"(Golgi-associated vesicle membrane)|go:"GO:0031301"(integral component of organelle membrane)|go:"GO:0042985"(negative regulation of amyloid precursor protein biosynthetic process)|interpro:IPR007084(BRICHOS)|interpro:IPR040145|mint:Q5XIE8|refseq:NP_001006964.1|rgd:620727	rgd:2679|refseq:NP_058705.2|ensembl:ENSRNOG00000002919(gene)|ensembl:ENSRNOT00000034401(transcript)|go:"GO:0005178"(integrin binding)|go:"GO:0005200"(structural constituent of cytoskeleton)|go:"GO:0005737"(cytoplasm)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005882"(intermediate filament)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0009611"(response to wounding)|go:"GO:0010467"(gene expression)|go:"GO:0010625"(positive regulation of Schwann cell proliferation)|go:"GO:0010977"(negative regulation of neuron projection development)|go:"GO:0014002"(astrocyte development)|go:"GO:0016020"(membrane)|go:"GO:0019900"(kinase binding)|go:"GO:0030198"(extracellular matrix organization)|go:"GO:0031102"(neuron projection regeneration)|go:"GO:0042802"(identical protein binding)|go:"GO:0042995"(cell projection)|go:"GO:0044297"(cell body)|go:"GO:0045103"(intermediate filament-based process)|go:"GO:0045109"(intermediate filament organization)|go:"GO:0051580"(regulation of neurotransmitter uptake)|go:"GO:0060020"(Bergmann glial cell differentiation)|go:"GO:0060252"(positive regulation of glial cell proliferation)|go:"GO:0060291"(long-term synaptic potentiation)|go:"GO:0070779"(D-aspartate import across plasma membrane)|go:"GO:0097386"(glial cell projection)|go:"GO:0097449"(astrocyte projection)|go:"GO:0097450"(astrocyte end-foot)|go:"GO:0098574"(cytoplasmic side of lysosomal membrane)|go:"GO:1904714"(regulation of chaperone-mediated autophagy)|interpro:IPR006821(Intermediate filament, DNA-binding region)|interpro:IPR018039|interpro:IPR027701|interpro:IPR039008|mint:P47819	-	-	-	figure legend:ST1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10116(rat-brain-cerebellum)|taxid:10116(Rattus norvegicus)	-	2020/10/30	2020/10/30	rogid:DtE+ZXAZKdCMvUW5K+jXQ5bH07M10116	rogid:ougdJqiJZjrvDV1vfVnCwcx9cFU10116	rigid:OaXQ9NA25fwCWxejPU3Ao9q5j/E	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q5XIE8	uniprotkb:P08050	intact:EBI-15348306|ensembl:ENSRNOP00000023037	intact:EBI-476947|uniprotkb:Q53ZE1|ensembl:ENSRNOP00000001054	psi-mi:itm2b_rat(display_long)|uniprotkb:Itm2b(gene name)|psi-mi:Itm2b(display_short)|uniprotkb:Immature BRI2(gene name synonym)|uniprotkb:Transmembrane protein BRI(gene name synonym)	psi-mi:cxa1_rat(display_long)|uniprotkb:Gja1(gene name)|psi-mi:Gja1(display_short)|uniprotkb:Cxn-43(gene name synonym)|uniprotkb:Connexin-43(gene name synonym)|uniprotkb:Gap junction 43 kDa heart protein(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Martins et al. (2018)	imex:IM-28469|pubmed:29476059	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26438079|imex:IM-28469-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSRNOG00000016271(gene)|ensembl:ENSRNOT00000023037(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001540"(amyloid-beta binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0010008"(endosome membrane)|go:"GO:0030660"(Golgi-associated vesicle membrane)|go:"GO:0031301"(integral component of organelle membrane)|go:"GO:0042985"(negative regulation of amyloid precursor protein biosynthetic process)|interpro:IPR007084(BRICHOS)|interpro:IPR040145|mint:Q5XIE8|refseq:NP_001006964.1|rgd:620727	go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0030500"(regulation of bone mineralization)|go:"GO:0030660"(Golgi-associated vesicle membrane)|go:"GO:0032024"(positive regulation of insulin secretion)|go:"GO:0032277"(negative regulation of gonadotropin secretion)|go:"GO:0032355"(response to estradiol)|go:"GO:0032496"(response to lipopolysaccharide)|go:"GO:0032526"(response to retinoic acid)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034220"(ion transmembrane transport)|go:"GO:0034405"(response to fluid shear stress)|go:"GO:0034613"(cellular protein localization)|go:"GO:0034634"(glutathione transmembrane transporter activity)|go:"GO:0035050"(embryonic heart tube development)|go:"GO:0035437"(maintenance of protein localization in endoplasmic reticulum)|go:"GO:0042098"(T cell proliferation)|go:"GO:0042110"(T cell activation)|go:"GO:0030165"(PDZ domain binding)|ensembl:ENSRNOT00000001054(transcript)|go:"GO:0000132"(establishment of mitotic spindle orientation)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001649"(osteoblast differentiation)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0001764"(neuron migration)|go:"GO:0001937"(negative regulation of endothelial cell proliferation)|go:"GO:0001947"(heart looping)|ensembl:ENSRNOG00000000805(gene)|go:"GO:0002070"(epithelial cell maturation)|go:"GO:0002088"(lens development in camera-type eye)|go:"GO:0002544"(chronic inflammatory response)|go:"GO:0002931"(response to ischemia)|go:"GO:0003104"(positive regulation of glomerular filtration)|go:"GO:0003158"(endothelium development)|go:"GO:0042311"(vasodilation)|go:"GO:0042733"(embryonic digit morphogenesis)|go:"GO:0042908"(xenobiotic transport)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0043292"(contractile fiber)|go:"GO:0043403"(skeletal muscle tissue regeneration)|go:"GO:0043434"(response to peptide hormone)|go:"GO:0044291"(cell-cell contact zone)|go:"GO:0045121"(membrane raft)|go:"GO:0045216"(cell-cell junction organization)|go:"GO:0045732"(positive regulation of protein catabolic process)|go:"GO:0045844"(positive regulation of striated muscle tissue development)|go:"GO:0045907"(positive regulation of vasoconstriction)|go:"GO:0046697"(decidualization)|go:"GO:0046849"(bone remodeling)|go:"GO:0046850"(regulation of bone remodeling)|go:"GO:0048487"(beta-tubulin binding)|go:"GO:0048514"(blood vessel morphogenesis)|go:"GO:0048812"(neuron projection morphogenesis)|go:"GO:0051924"(regulation of calcium ion transport)|go:"GO:0055077"(gap junction hemi-channel activity)|go:"GO:0055085"(transmembrane transport)|go:"GO:0060044"(negative regulation of cardiac muscle cell proliferation)|go:"GO:0060156"(milk ejection reflex)|go:"GO:0060307"(regulation of ventricular cardiac muscle cell membrane repolarization)|go:"GO:0060348"(bone development)|go:"GO:0060371"(regulation of atrial cardiac muscle cell membrane depolarization)|go:"GO:0060373"(regulation of ventricular cardiac muscle cell membrane depolarization)|go:"GO:0061045"(negative regulation of wound healing)|go:"GO:0061337"(cardiac conduction)|go:"GO:0070160"(tight junction)|go:"GO:0071253"(connexin binding)|go:"GO:0071260"(cellular response to mechanical stimulus)|go:"GO:0071374"(cellular response to parathyroid hormone stimulus)|go:"GO:0071467"(cellular response to pH)|go:"GO:0097110"(scaffold protein binding)|go:"GO:0003294"(atrial ventricular junction remodeling)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005243"(gap junction channel activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005764"(lysosome)|go:"GO:0005768"(endosome)|go:"GO:0005769"(early endosome)|go:"GO:0005770"(late endosome)|go:"GO:0005771"(multivesicular body)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0005882"(intermediate filament)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0097718"(disordered domain specific binding)|go:"GO:0099111"(microtubule-based transport)|go:"GO:1904646"(cellular response to amyloid-beta)|go:"GO:0120162"(positive regulation of cold-induced thermogenesis)|go:"GO:1904707"(positive regulation of vascular associated smooth muscle cell proliferation)|go:"GO:1905332"(positive regulation of morphogenesis of an epithelium)|go:"GO:1905772"(positive regulation of mesodermal cell differentiation)|go:"GO:0140115"(export across plasma membrane)|go:"GO:1905867"(epididymis development)|go:"GO:1901164"(negative regulation of trophoblast cell migration)|go:"GO:1990782"(protein tyrosine kinase binding)|go:"GO:2000279"(negative regulation of DNA biosynthetic process)|go:"GO:2000648"(positive regulation of stem cell proliferation)|go:"GO:2000810"(regulation of bicellular tight junction assembly)|go:"GO:2000987"(positive regulation of behavioral fear response)|interpro:IPR000500(Connexins)|go:"GO:1903763"(gap junction channel activity involved in cell communication by electrical coupling)|interpro:IPR002261("Gap junction alpha-1 protein (Cx43)")|interpro:IPR013092(Connexin, N-terminal)|interpro:IPR013124("Gap junction alpha-1 protein (Cx43), C-terminal")|interpro:IPR017990|interpro:IPR019570|interpro:IPR034634|interpro:IPR035091|interpro:IPR038359|mint:P08050|rcsb pdb:1R5S|rcsb pdb:2N8T|rcsb pdb:3CYY|reactome:R-RNO-190840|reactome:R-RNO-190861|reactome:R-RNO-190873|reactome:R-RNO-191650|reactome:R-RNO-196025|reactome:R-RNO-9013406|go:"GO:0005916"(fascia adherens)|go:"GO:0008584"(male gonad development)|go:"GO:0009268"(response to pH)|go:"GO:0005921"(gap junction)|go:"GO:0005922"(connexin complex)|go:"GO:0009749"(response to glucose)|go:"GO:0010232"(vascular transport)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0010643"(cell communication by chemical coupling)|go:"GO:0010644"(cell communication by electrical coupling)|go:"GO:0010649"(regulation of cell communication by electrical coupling)|go:"GO:0010652"(positive regulation of cell communication by chemical coupling)|go:"GO:0014047"(glutamate secretion)|go:"GO:0014704"(intercalated disc)|go:"GO:0015075"(ion transmembrane transporter activity)|go:"GO:0015562"(efflux transmembrane transporter activity)|go:"GO:0015631"(tubulin binding)|go:"GO:0015867"(ATP transport)|go:"GO:0016020"(membrane)|go:"GO:0016264"(gap junction assembly)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0016328"(lateral plasma membrane)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0006915"(apoptotic process)|go:"GO:0022898"(regulation of transmembrane transporter activity)|go:"GO:0007154"(cell communication)|go:"GO:0030054"(cell junction)|go:"GO:0007165"(signal transduction)|go:"GO:0007204"(positive regulation of cytosolic calcium ion concentration)|go:"GO:0007267"(cell-cell signaling)|go:"GO:0007283"(spermatogenesis)|go:"GO:0007507"(heart development)|go:"GO:0007512"(adult heart development)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0008016"(regulation of heart contraction)|go:"GO:0008285"(negative regulation of cell population proliferation)|rgd:2690|refseq:NP_036699.1|dip:DIP-34793N	-	-	-	figure legend:ST1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10116(rat-brain-cerebellum)|taxid:10116(Rattus norvegicus)	-	2020/10/30	2020/10/30	rogid:DtE+ZXAZKdCMvUW5K+jXQ5bH07M10116	rogid:qRGPHCApRj9/xiPxo1KW9D/xE5w10116	rigid:OaXQ9NA25fwCWxejPU3Ao9q5j/E	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q5XIE8	uniprotkb:P31596	intact:EBI-15348306|ensembl:ENSRNOP00000023037	intact:EBI-2649895	psi-mi:itm2b_rat(display_long)|uniprotkb:Itm2b(gene name)|psi-mi:Itm2b(display_short)|uniprotkb:Immature BRI2(gene name synonym)|uniprotkb:Transmembrane protein BRI(gene name synonym)	psi-mi:eaa2_rat(display_long)|uniprotkb:Slc1a2(gene name)|psi-mi:Slc1a2(display_short)|uniprotkb:Eaat2(gene name synonym)|uniprotkb:Glt1(gene name synonym)|uniprotkb:Sodium-dependent glutamate/aspartate transporter 2(gene name synonym)|uniprotkb:GLT-1(gene name synonym)|uniprotkb:Solute carrier family 1 member 2(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Martins et al. (2018)	imex:IM-28469|pubmed:29476059	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26438079|imex:IM-28469-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSRNOG00000016271(gene)|ensembl:ENSRNOT00000023037(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001540"(amyloid-beta binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0010008"(endosome membrane)|go:"GO:0030660"(Golgi-associated vesicle membrane)|go:"GO:0031301"(integral component of organelle membrane)|go:"GO:0042985"(negative regulation of amyloid precursor protein biosynthetic process)|interpro:IPR007084(BRICHOS)|interpro:IPR040145|mint:Q5XIE8|refseq:NP_001006964.1|rgd:620727	mint:P31596|rgd:3697|refseq:NP_058911.2|interpro:IPR001991("Sodium:dicarboxylate symporter")|interpro:IPR018107|refseq:NP_001289018.1|go:"GO:0005313"(L-glutamate transmembrane transporter activity)|go:"GO:0005314"(high-affinity glutamate transmembrane transporter activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006750"(glutathione biosynthetic process)|go:"GO:0006836"(neurotransmitter transport)|go:"GO:0007399"(nervous system development)|go:"GO:0007632"(visual behavior)|go:"GO:0008509"(anion transmembrane transporter activity)|go:"GO:0009416"(response to light stimulus)|go:"GO:0009611"(response to wounding)|go:"GO:0009986"(cell surface)|go:"GO:0010259"(multicellular organism aging)|go:"GO:0015501"("glutamate:sodium symporter activity")|go:"GO:0015813"(L-glutamate transmembrane transport)|go:"GO:0016020"(membrane)|go:"GO:0021537"(telencephalon development)|go:"GO:0030424"(axon)|go:"GO:0030534"(adult behavior)|go:"GO:0030673"(axolemma)|go:"GO:0031668"(cellular response to extracellular stimulus)|go:"GO:0031982"(vesicle)|go:"GO:0033229"(cysteine transmembrane transporter activity)|go:"GO:0035264"(multicellular organism growth)|go:"GO:0042493"|go:"GO:0042734"(presynaptic membrane)|go:"GO:0043005"(neuron projection)|go:"GO:0043197"(dendritic spine)|go:"GO:0043198"(dendritic shaft)|go:"GO:0043200"(response to amino acid)|go:"GO:0044297"(cell body)|go:"GO:0044306"(neuron projection terminus)|go:"GO:0045121"(membrane raft)|go:"GO:0045202"(synapse)|go:"GO:0046326"(positive regulation of glucose import)|go:"GO:0046872"(metal ion binding)|go:"GO:0070207"(protein homotrimerization)|go:"GO:0070779"(D-aspartate import across plasma membrane)|go:"GO:0071314"(cellular response to cocaine)|go:"GO:0097449"(astrocyte projection)|go:"GO:0098656"(anion transmembrane transport)|go:"GO:0098712"(L-glutamate import across plasma membrane)|go:"GO:0098796"(membrane protein complex)|go:"GO:0098810"(neurotransmitter reuptake)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099056"(integral component of presynaptic membrane)|reactome:R-RNO-210455|reactome:R-RNO-210500|reactome:R-RNO-425393|interpro:IPR036458	-	-	-	figure legend:ST1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10116(rat-brain-cerebellum)|taxid:10116(Rattus norvegicus)	-	2020/10/30	2020/10/30	rogid:DtE+ZXAZKdCMvUW5K+jXQ5bH07M10116	rogid:JednhWybRDznXCugAtjbnX/1JmM10116	rigid:OaXQ9NA25fwCWxejPU3Ao9q5j/E	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q5XIE8	uniprotkb:P24942	intact:EBI-15348306|ensembl:ENSRNOP00000023037	intact:EBI-26373259|uniprotkb:Q9JK43	psi-mi:itm2b_rat(display_long)|uniprotkb:Itm2b(gene name)|psi-mi:Itm2b(display_short)|uniprotkb:Immature BRI2(gene name synonym)|uniprotkb:Transmembrane protein BRI(gene name synonym)	psi-mi:eaa1_rat(display_long)|uniprotkb:Glial glutamate transporter(gene name synonym)|uniprotkb:Sodium-dependent glutamate/aspartate transporter 1(gene name synonym)|uniprotkb:Solute carrier family 1 member 3(gene name synonym)|uniprotkb:Slc1a3(gene name)|psi-mi:Slc1a3(display_short)|uniprotkb:Eaat1(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Martins et al. (2018)	imex:IM-28469|pubmed:29476059	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26438079|imex:IM-28469-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSRNOG00000016271(gene)|ensembl:ENSRNOT00000023037(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001540"(amyloid-beta binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0010008"(endosome membrane)|go:"GO:0030660"(Golgi-associated vesicle membrane)|go:"GO:0031301"(integral component of organelle membrane)|go:"GO:0042985"(negative regulation of amyloid precursor protein biosynthetic process)|interpro:IPR007084(BRICHOS)|interpro:IPR040145|mint:Q5XIE8|refseq:NP_001006964.1|rgd:620727	go:"GO:0015172"(acidic amino acid transmembrane transporter activity)|go:"GO:0015501"("glutamate:sodium symporter activity")|go:"GO:0015813"(L-glutamate transmembrane transport)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016595"(glutamate binding)|go:"GO:0016597"(amino acid binding)|go:"GO:0021545"(cranial nerve development)|go:"GO:0031223"(auditory behavior)|go:"GO:0042493"|go:"GO:0042995"(cell projection)|go:"GO:0043005"(neuron projection)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043197"(dendritic spine)|go:"GO:0043490"(malate-aspartate shuttle)|go:"GO:0045202"(synapse)|go:"GO:0046677"(response to antibiotic)|go:"GO:0046872"(metal ion binding)|go:"GO:0048667"(cell morphogenesis involved in neuron differentiation)|go:"GO:0050806"(positive regulation of synaptic transmission)|go:"GO:0050885"(neuromuscular process controlling balance)|go:"GO:0051938"(L-glutamate import)|go:"GO:0070779"(D-aspartate import across plasma membrane)|go:"GO:0071314"(cellular response to cocaine)|go:"GO:0071805"(potassium ion transmembrane transport)|go:"GO:0071944"(cell periphery)|go:"GO:0098712"(L-glutamate import across plasma membrane)|go:"GO:0005313"(L-glutamate transmembrane transporter activity)|go:"GO:0005314"(high-affinity glutamate transmembrane transporter activity)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006836"(neurotransmitter transport)|go:"GO:0006883"(cellular sodium ion homeostasis)|go:"GO:0007605"(sensory perception of sound)|go:"GO:0009416"(response to light stimulus)|go:"GO:0009449"(gamma-aminobutyric acid biosynthetic process)|go:"GO:0009611"(response to wounding)|go:"GO:0009925"(basal plasma membrane)|go:"GO:0009986"(cell surface)|go:"GO:0010035"(response to inorganic substance)|go:"GO:0098796"(membrane protein complex)|go:"GO:0140009"(L-aspartate import across plasma membrane)|go:"GO:1902476"(chloride transmembrane transport)|reactome:R-RNO-210455|reactome:R-RNO-210500|reactome:R-RNO-425393|rgd:3698|mint:P24942|refseq:NP_001276870.1|refseq:NP_001276871.1|refseq:NP_001276872.1|refseq:NP_062098.1|interpro:IPR001991("Sodium:dicarboxylate symporter")|interpro:IPR018107|interpro:IPR036458	-	-	-	figure legend:ST1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10116(rat-brain-cerebellum)|taxid:10116(Rattus norvegicus)	-	2020/10/30	2020/10/30	rogid:DtE+ZXAZKdCMvUW5K+jXQ5bH07M10116	rogid:c22nOB/elZ8k3t1KJiZ3jyW+aSs10116	rigid:OaXQ9NA25fwCWxejPU3Ao9q5j/E	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q5XIE8	uniprotkb:Q66HD0	intact:EBI-15348306|ensembl:ENSRNOP00000023037	intact:EBI-6249734|uniprotkb:A6IFJ6	psi-mi:itm2b_rat(display_long)|uniprotkb:Itm2b(gene name)|psi-mi:Itm2b(display_short)|uniprotkb:Immature BRI2(gene name synonym)|uniprotkb:Transmembrane protein BRI(gene name synonym)	psi-mi:enpl_rat(display_long)|uniprotkb:Hsp90b1(gene name)|psi-mi:Hsp90b1(display_short)|uniprotkb:Grp94(gene name synonym)|uniprotkb:Tra1(gene name synonym)|uniprotkb:94 kDa glucose-regulated protein(gene name synonym)|uniprotkb:Heat shock protein 90 kDa beta member 1(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Martins et al. (2018)	imex:IM-28469|pubmed:29476059	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26438079|imex:IM-28469-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSRNOG00000016271(gene)|ensembl:ENSRNOT00000023037(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001540"(amyloid-beta binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0010008"(endosome membrane)|go:"GO:0030660"(Golgi-associated vesicle membrane)|go:"GO:0031301"(integral component of organelle membrane)|go:"GO:0042985"(negative regulation of amyloid precursor protein biosynthetic process)|interpro:IPR007084(BRICHOS)|interpro:IPR040145|mint:Q5XIE8|refseq:NP_001006964.1|rgd:620727	mint:Q66HD0|rgd:1310482|refseq:NP_001012197.2|interpro:IPR003594(ATP-binding region, ATPase-like)|interpro:IPR019805|interpro:IPR001404(Heat shock protein Hsp90)|interpro:IPR020575|interpro:IPR020568|go:"GO:0001666"(response to hypoxia)|go:"GO:0003723"(RNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005788"(endoplasmic reticulum lumen)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005790"(smooth endoplasmic reticulum)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006457"(protein folding)|go:"GO:0019903"(protein phosphatase binding)|go:"GO:0030433"(ubiquitin-dependent ERAD pathway)|go:"GO:0030496"(midbody)|go:"GO:0030970"(retrograde protein transport, ER to cytosol)|go:"GO:0031247"(actin rod assembly)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033018"(sarcoplasmic reticulum lumen)|go:"GO:0034663"(endoplasmic reticulum chaperone complex)|go:"GO:0042470"(melanosome)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043666"(regulation of phosphoprotein phosphatase activity)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0050750"(low-density lipoprotein particle receptor binding)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0071287"(cellular response to manganese ion)|go:"GO:0071318"(cellular response to ATP)|reactome:R-RNO-1679131|reactome:R-RNO-3000480|reactome:R-RNO-381426|reactome:R-RNO-6785807|reactome:R-RNO-8957275|interpro:IPR036890|interpro:IPR037196	-	-	-	figure legend:ST1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10116(rat-brain-cerebellum)|taxid:10116(Rattus norvegicus)	-	2020/10/30	2020/10/30	rogid:DtE+ZXAZKdCMvUW5K+jXQ5bH07M10116	rogid:KSJbfWJ3pXbaBW15MDZ6syUs/4U10116	rigid:OaXQ9NA25fwCWxejPU3Ao9q5j/E	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q5XIE8	uniprotkb:Q5PPJ9	intact:EBI-15348306|ensembl:ENSRNOP00000023037	intact:EBI-8848640	psi-mi:itm2b_rat(display_long)|uniprotkb:Itm2b(gene name)|psi-mi:Itm2b(display_short)|uniprotkb:Immature BRI2(gene name synonym)|uniprotkb:Transmembrane protein BRI(gene name synonym)	psi-mi:shlb2_rat(display_long)|uniprotkb:Sh3glb2(gene name)|psi-mi:Sh3glb2(display_short)|uniprotkb:SH3 domain-containing GRB2-like protein B2(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Martins et al. (2018)	imex:IM-28469|pubmed:29476059	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26438079|imex:IM-28469-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSRNOG00000016271(gene)|ensembl:ENSRNOT00000023037(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001540"(amyloid-beta binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0010008"(endosome membrane)|go:"GO:0030660"(Golgi-associated vesicle membrane)|go:"GO:0031301"(integral component of organelle membrane)|go:"GO:0042985"(negative regulation of amyloid precursor protein biosynthetic process)|interpro:IPR007084(BRICHOS)|interpro:IPR040145|mint:Q5XIE8|refseq:NP_001006964.1|rgd:620727	mint:Q5PPJ9|interpro:IPR027267|interpro:IPR004148(BAR)|interpro:IPR001452(Src homology-3)|refseq:NP_001009692.1|rgd:1305886|refseq:XP_006233880.1|interpro:IPR035640|interpro:IPR036028|go:"GO:0005737"(cytoplasm)|go:"GO:0042802"(identical protein binding)	-	-	-	figure legend:ST1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10116(rat-brain-cerebellum)|taxid:10116(Rattus norvegicus)	-	2020/10/30	2020/10/30	rogid:DtE+ZXAZKdCMvUW5K+jXQ5bH07M10116	rogid:Zm8xh0SeU1baeRfRtOvo8uae/n810116	rigid:OaXQ9NA25fwCWxejPU3Ao9q5j/E	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q5XIE8	uniprotkb:P85834	intact:EBI-15348306|ensembl:ENSRNOP00000023037	intact:EBI-2640608|ensembl:ENSRNOP00000025203	psi-mi:itm2b_rat(display_long)|uniprotkb:Itm2b(gene name)|psi-mi:Itm2b(display_short)|uniprotkb:Immature BRI2(gene name synonym)|uniprotkb:Transmembrane protein BRI(gene name synonym)	psi-mi:eftu_rat(display_long)|uniprotkb:Tufm(gene name)|psi-mi:Tufm(display_short)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Martins et al. (2018)	imex:IM-28469|pubmed:29476059	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26438079|imex:IM-28469-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSRNOG00000016271(gene)|ensembl:ENSRNOT00000023037(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001540"(amyloid-beta binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0010008"(endosome membrane)|go:"GO:0030660"(Golgi-associated vesicle membrane)|go:"GO:0031301"(integral component of organelle membrane)|go:"GO:0042985"(negative regulation of amyloid precursor protein biosynthetic process)|interpro:IPR007084(BRICHOS)|interpro:IPR040145|mint:Q5XIE8|refseq:NP_001006964.1|rgd:620727	rgd:1305501|refseq:NP_001099765.1|ensembl:ENSRNOG00000018604(gene)|ensembl:ENSRNOT00000025203(transcript)|go:"GO:0003746"(translation elongation factor activity)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005739"(mitochondrion)|go:"GO:0006414"(translational elongation)|go:"GO:0042645"(mitochondrial nucleoid)|go:"GO:0045202"(synapse)|go:"GO:0045471"(response to ethanol)|go:"GO:0070125"(mitochondrial translational elongation)|interpro:IPR000795(Protein synthesis factor, GTP-binding)|interpro:IPR004160(Translation elongation factor EFTu/EF1A, C-terminal)|interpro:IPR004161(Translation elongation factor EFTu/EF1A, domain 2)|interpro:IPR004541(Translation elongation factor EFTu/EF1A, bacterial and organelle)|interpro:IPR009000(Translation elongation and initiation factors/Ribosomal, beta-barrel)|interpro:IPR009001(Translation elongation factor EF1A/initiation factor IF2gamma, C-terminal)|interpro:IPR027417|interpro:IPR031157|interpro:IPR033720|interpro:IPR041709|mint:P85834	-	-	-	figure legend:ST1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10116(rat-brain-cerebellum)|taxid:10116(Rattus norvegicus)	-	2020/10/30	2020/10/30	rogid:DtE+ZXAZKdCMvUW5K+jXQ5bH07M10116	rogid:7ijVJSb0XSiqlNjp70i4FXEF2z810116	rigid:OaXQ9NA25fwCWxejPU3Ao9q5j/E	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q5XIE8	uniprotkb:P05197	intact:EBI-15348306|ensembl:ENSRNOP00000023037	intact:EBI-915895|uniprotkb:P97619|ensembl:ENSRNOP00000041821	psi-mi:itm2b_rat(display_long)|uniprotkb:Itm2b(gene name)|psi-mi:Itm2b(display_short)|uniprotkb:Immature BRI2(gene name synonym)|uniprotkb:Transmembrane protein BRI(gene name synonym)	psi-mi:ef2_rat(display_long)|uniprotkb:Eef2(gene name)|psi-mi:Eef2(display_short)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Martins et al. (2018)	imex:IM-28469|pubmed:29476059	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26438079|imex:IM-28469-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSRNOG00000016271(gene)|ensembl:ENSRNOT00000023037(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001540"(amyloid-beta binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0010008"(endosome membrane)|go:"GO:0030660"(Golgi-associated vesicle membrane)|go:"GO:0031301"(integral component of organelle membrane)|go:"GO:0042985"(negative regulation of amyloid precursor protein biosynthetic process)|interpro:IPR007084(BRICHOS)|interpro:IPR040145|mint:Q5XIE8|refseq:NP_001006964.1|rgd:620727	rgd:61979|refseq:NP_058941.1|ensembl:ENSRNOG00000020266(gene)|ensembl:ENSRNOT00000047450(transcript)|go:"GO:0002039"(p53 binding)|go:"GO:0002244"(hematopoietic progenitor cell differentiation)|go:"GO:0002931"(response to ischemia)|go:"GO:0003009"(skeletal muscle contraction)|go:"GO:0003723"(RNA binding)|go:"GO:0003746"(translation elongation factor activity)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005844"(polysome)|go:"GO:0005886"(plasma membrane)|go:"GO:0006414"(translational elongation)|go:"GO:0007568"(aging)|go:"GO:0008097"(5S rRNA binding)|go:"GO:0014009"(glial cell proliferation)|go:"GO:0016235"(aggresome)|go:"GO:0019901"(protein kinase binding)|go:"GO:0032355"(response to estradiol)|go:"GO:0034976"(response to endoplasmic reticulum stress)|go:"GO:0035914"(skeletal muscle cell differentiation)|go:"GO:0042493"|go:"GO:0042542"(response to hydrogen peroxide)|go:"GO:0042788"(polysomal ribosome)|go:"GO:0043022"(ribosome binding)|go:"GO:0045121"(membrane raft)|go:"GO:0045202"(synapse)|go:"GO:0045471"(response to ethanol)|go:"GO:0045727"(positive regulation of translation)|go:"GO:0051015"(actin filament binding)|go:"GO:0051593"(response to folic acid)|go:"GO:1990416"(cellular response to brain-derived neurotrophic factor stimulus)|go:"GO:1990904"(ribonucleoprotein complex)|go:"GO:2000767"(positive regulation of cytoplasmic translation)|interpro:IPR000640(Translation elongation factor EFG/EF2, C-terminal)|interpro:IPR000795(Protein synthesis factor, GTP-binding)|interpro:IPR004161(Translation elongation factor EFTu/EF1A, domain 2)|interpro:IPR005225(Small GTP-binding protein)|interpro:IPR005517(Translation elongation factor EFG/EF2, domain IV)|interpro:IPR009000(Translation elongation and initiation factors/Ribosomal, beta-barrel)|interpro:IPR014721(Ribosomal protein S5 domain 2-type fold)|interpro:IPR020568|interpro:IPR027417|interpro:IPR031157|interpro:IPR035647|interpro:IPR041095|mint:P05197|reactome:R-RNO-156902|reactome:R-RNO-5358493|reactome:R-RNO-6798695	-	-	-	figure legend:ST1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10116(rat-brain-cerebellum)|taxid:10116(Rattus norvegicus)	-	2020/10/30	2020/10/30	rogid:DtE+ZXAZKdCMvUW5K+jXQ5bH07M10116	rogid:JpTfRnV5VR9V+mR+c5hxYJ0FsM410116	rigid:OaXQ9NA25fwCWxejPU3Ao9q5j/E	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q5XIE8	uniprotkb:P31016	intact:EBI-15348306|ensembl:ENSRNOP00000023037	intact:EBI-375655|uniprotkb:P97631|ensembl:ENSRNOP00000059045	psi-mi:itm2b_rat(display_long)|uniprotkb:Itm2b(gene name)|psi-mi:Itm2b(display_short)|uniprotkb:Immature BRI2(gene name synonym)|uniprotkb:Transmembrane protein BRI(gene name synonym)	psi-mi:dlg4_rat(display_long)|uniprotkb:Dlg4(gene name)|psi-mi:Dlg4(display_short)|uniprotkb:Dlgh4(gene name synonym)|uniprotkb:Postsynaptic density protein 95(gene name synonym)|uniprotkb:Synapse-associated protein 90(gene name synonym)|uniprotkb:Psd95(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Martins et al. (2018)	imex:IM-28469|pubmed:29476059	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26438079|imex:IM-28469-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSRNOG00000016271(gene)|ensembl:ENSRNOT00000023037(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001540"(amyloid-beta binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0010008"(endosome membrane)|go:"GO:0030660"(Golgi-associated vesicle membrane)|go:"GO:0031301"(integral component of organelle membrane)|go:"GO:0042985"(negative regulation of amyloid precursor protein biosynthetic process)|interpro:IPR007084(BRICHOS)|interpro:IPR040145|mint:Q5XIE8|refseq:NP_001006964.1|rgd:620727	go:"GO:0030165"(PDZ domain binding)|go:"GO:0030425"(dendrite)|go:"GO:0030863"(cortical cytoskeleton)|go:"GO:0031234"(extrinsic component of cytoplasmic side of plasma membrane)|go:"GO:0031594"(neuromuscular junction)|go:"GO:0031697"(beta-1 adrenergic receptor binding)|go:"GO:0031698"(beta-2 adrenergic receptor binding)|go:"GO:0031748"(D1 dopamine receptor binding)|go:"GO:0031812"(P2Y1 nucleotide receptor binding)|go:"GO:0032281"(AMPA glutamate receptor complex)|go:"GO:0032839"(dendrite cytoplasm)|go:"GO:0033130"(acetylcholine receptor binding)|go:"GO:0035176"(social behavior)|go:"GO:0035254"(glutamate receptor binding)|go:"GO:0035255"(ionotropic glutamate receptor binding)|go:"GO:0035418"(protein localization to synapse)|go:"GO:0035641"(locomotory exploration behavior)|go:"GO:0035865"(cellular response to potassium ion)|go:"GO:0043005"(neuron projection)|go:"GO:0043113"(receptor clustering)|go:"GO:0043197"(dendritic spine)|go:"GO:0044224"(juxtaparanode region of axon)|go:"GO:0044300"(cerebellar mossy fiber)|go:"GO:0044306"(neuron projection terminus)|go:"GO:0044309"(neuron spine)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045161"(neuronal ion channel clustering)|go:"GO:0045184"(establishment of protein localization)|go:"GO:0045202"(synapse)|go:"GO:0045211"(postsynaptic membrane)|go:"GO:0048168"(regulation of neuronal synaptic plasticity)|go:"GO:0048169"(regulation of long-term neuronal synaptic plasticity)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0050806"(positive regulation of synaptic transmission)|go:"GO:0050885"(neuromuscular process controlling balance)|go:"GO:0060076"(excitatory synapse)|go:"GO:0060997"(dendritic spine morphogenesis)|go:"GO:0061098"(positive regulation of protein tyrosine kinase activity)|go:"GO:0099031"(anchored component of postsynaptic density membrane)|go:"GO:0065003"(protein-containing complex assembly)|go:"GO:0071625"(vocalization behavior)|go:"GO:0071944"(cell periphery)|go:"GO:0097060"(synaptic membrane)|go:"GO:0097061"(dendritic spine organization)|go:"GO:0097109"(neuroligin family protein binding)|go:"GO:0099645"(neurotransmitter receptor localization to postsynaptic specialization membrane)|go:"GO:0150012"(positive regulation of neuron projection arborization)|go:"GO:0097110"(scaffold protein binding)|go:"GO:1904719"(positive regulation of AMPA glutamate receptor clustering)|go:"GO:0097113"(AMPA glutamate receptor clustering)|go:"GO:0097120"(receptor localization to synapse)|go:"GO:0098609"(cell-cell adhesion)|go:"GO:0098794"(postsynapse)|go:"GO:0098839"(postsynaptic density membrane)|go:"GO:0098919"(structural constituent of postsynaptic density)|go:"GO:0098970"(postsynaptic neurotransmitter receptor diffusion trapping)|go:"GO:2000310"(regulation of NMDA receptor activity)|go:"GO:2000463"(positive regulation of excitatory postsynaptic potential)|go:"GO:2000821"(regulation of grooming behavior)|interpro:IPR001452(Src homology-3)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR008144(Guanylate kinase)|interpro:IPR008145(Guanylate kinase/L-type calcium channel region)|rcsb pdb:1TP3|interpro:IPR016313("Membrane-associated guanylate kinase (MAGUK) scaffold protein")|interpro:IPR019583|interpro:IPR019590|interpro:IPR020590|interpro:IPR027417|interpro:IPR036028|interpro:IPR036034|mint:P31016|rcsb pdb:1BE9|rcsb pdb:1BFE|rcsb pdb:1IU0|rcsb pdb:1IU2|rcsb pdb:1JXM|rcsb pdb:1JXO|rcsb pdb:1KJW|rcsb pdb:1QLC|rcsb pdb:1RGR|rcsb pdb:5MZ7|rcsb pdb:5W72|rcsb pdb:5YPO|rcsb pdb:5YPR|rcsb pdb:7CQF|reactome:R-RNO-399719|reactome:R-RNO-438066|reactome:R-RNO-451308|reactome:R-RNO-5625900|reactome:R-RNO-5673001|reactome:R-RNO-5682910|reactome:R-RNO-6794361|reactome:R-RNO-8849932|rcsb pdb:1TP5|rcsb pdb:1TQ3|rcsb pdb:2KA9|rcsb pdb:2MHO|rcsb pdb:2XKX|rcsb pdb:3GSL|rcsb pdb:3WP0|rcsb pdb:3WP1|rcsb pdb:5B64|rcsb pdb:5D13|rcsb pdb:5GNV|rcsb pdb:5HDY|rcsb pdb:5HEB|rcsb pdb:5HED|rcsb pdb:5HET|rcsb pdb:5HEY|rcsb pdb:5HF1|rcsb pdb:5HF4|rcsb pdb:5HFB|rcsb pdb:5HFC|rcsb pdb:5HFD|rcsb pdb:5HFE|rcsb pdb:5HFF|ensembl:ENSRNOG00000018526(gene)|ensembl:ENSRNOT00000068493(transcript)|go:"GO:0002091"(negative regulation of receptor internalization)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005109"(frizzled binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0007204"(positive regulation of cytosolic calcium ion concentration)|go:"GO:0007268"(chemical synaptic transmission)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008328"(ionotropic glutamate receptor complex)|go:"GO:0014069"(postsynaptic density)|go:"GO:0016020"(membrane)|go:"GO:0016188"(synaptic vesicle maturation)|go:"GO:0019865"(immunoglobulin binding)|go:"GO:0019894"(kinesin binding)|go:"GO:0019900"(kinase binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0019903"(protein phosphatase binding)|go:"GO:0030054"(cell junction)|rgd:68424|refseq:NP_062567.1|dip:DIP-29264N	-	-	-	figure legend:ST1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10116(rat-brain-cerebellum)|taxid:10116(Rattus norvegicus)	-	2020/10/30	2020/10/30	rogid:DtE+ZXAZKdCMvUW5K+jXQ5bH07M10116	rogid:4oWbxT/HVvWQqdbFqt3htRuQNpw10116	rigid:OaXQ9NA25fwCWxejPU3Ao9q5j/E	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q5XIE8	uniprotkb:P25809	intact:EBI-15348306|ensembl:ENSRNOP00000023037	intact:EBI-2255977	psi-mi:itm2b_rat(display_long)|uniprotkb:Itm2b(gene name)|psi-mi:Itm2b(display_short)|uniprotkb:Immature BRI2(gene name synonym)|uniprotkb:Transmembrane protein BRI(gene name synonym)	psi-mi:kcru_rat(display_long)|uniprotkb:Ckmt1(gene name)|psi-mi:Ckmt1(display_short)|uniprotkb:Ckmt(gene name synonym)|uniprotkb:Ubiquitous mitochondrial creatine kinase(gene name synonym)|uniprotkb:Acidic-type mitochondrial creatine kinase(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Martins et al. (2018)	imex:IM-28469|pubmed:29476059	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26438079|imex:IM-28469-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSRNOG00000016271(gene)|ensembl:ENSRNOT00000023037(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001540"(amyloid-beta binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0010008"(endosome membrane)|go:"GO:0030660"(Golgi-associated vesicle membrane)|go:"GO:0031301"(integral component of organelle membrane)|go:"GO:0042985"(negative regulation of amyloid precursor protein biosynthetic process)|interpro:IPR007084(BRICHOS)|interpro:IPR040145|mint:Q5XIE8|refseq:NP_001006964.1|rgd:620727	rgd:61976|interpro:IPR022415|interpro:IPR022414|interpro:IPR022413|interpro:IPR014746(Glutamine synthetase/guanido kinase, catalytic region)|interpro:IPR000749("ATP:guanido phosphotransferase")|mint:P25809|interpro:IPR036802|go:"GO:0001822"(kidney development)|go:"GO:0004111"(creatine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0007420"(brain development)|go:"GO:0007519"(skeletal muscle tissue development)|go:"GO:0016301"(kinase activity)|go:"GO:0021549"(cerebellum development)|go:"GO:0032091"(negative regulation of protein binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043204"(perikaryon)|go:"GO:0044289"(mitochondrial inner-outer membrane contact site)|go:"GO:0046314"(phosphocreatine biosynthetic process)|go:"GO:0048565"(digestive tract development)|reactome:R-RNO-71288	-	-	-	figure legend:ST1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10116(rat-brain-cerebellum)|taxid:10116(Rattus norvegicus)	-	2020/10/30	2020/10/30	rogid:DtE+ZXAZKdCMvUW5K+jXQ5bH07M10116	rogid:P0XRQOCYb/CdvJW7dt9XOvxDJ4Y10116	rigid:OaXQ9NA25fwCWxejPU3Ao9q5j/E	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q5XIE8	uniprotkb:P31721	intact:EBI-15348306|ensembl:ENSRNOP00000023037	intact:EBI-26437724	psi-mi:itm2b_rat(display_long)|uniprotkb:Itm2b(gene name)|psi-mi:Itm2b(display_short)|uniprotkb:Immature BRI2(gene name synonym)|uniprotkb:Transmembrane protein BRI(gene name synonym)	psi-mi:c1qb_rat(display_long)|uniprotkb:C1qb(gene name)|psi-mi:C1qb(display_short)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Martins et al. (2018)	imex:IM-28469|pubmed:29476059	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26438079|imex:IM-28469-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSRNOG00000016271(gene)|ensembl:ENSRNOT00000023037(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001540"(amyloid-beta binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0010008"(endosome membrane)|go:"GO:0030660"(Golgi-associated vesicle membrane)|go:"GO:0031301"(integral component of organelle membrane)|go:"GO:0042985"(negative regulation of amyloid precursor protein biosynthetic process)|interpro:IPR007084(BRICHOS)|interpro:IPR040145|mint:Q5XIE8|refseq:NP_001006964.1|rgd:620727	go:"GO:0005581"(collagen trimer)|go:"GO:0005602"(complement component C1 complex)|go:"GO:0006955"(immune response)|go:"GO:0006958"(complement activation, classical pathway)|go:"GO:0007420"(brain development)|go:"GO:0007568"(aging)|go:"GO:0010033"(response to organic substance)|go:"GO:0042802"(identical protein binding)|go:"GO:0045087"(innate immune response)|go:"GO:0045202"(synapse)|go:"GO:0048839"(inner ear development)|go:"GO:0051384"(response to glucocorticoid)|go:"GO:0098794"(postsynapse)|go:"GO:0098883"(synapse pruning)|reactome:R-RNO-166663|reactome:R-RNO-173623|reactome:R-RNO-977606|mint:P31721|refseq:NP_062135.1|interpro:IPR001073(Complement C1q protein)|interpro:IPR008160(Collagen triple helix repeat)|interpro:IPR037573|interpro:IPR008983(Tumour necrosis factor-like)|rgd:2229	-	-	-	figure legend:ST1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10116(rat-brain-cerebellum)|taxid:10116(Rattus norvegicus)	-	2020/10/30	2020/10/30	rogid:DtE+ZXAZKdCMvUW5K+jXQ5bH07M10116	rogid:2+DKSXCWFTd8r4uTtwJf8hdJqMQ10116	rigid:OaXQ9NA25fwCWxejPU3Ao9q5j/E	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q5XIE8	uniprotkb:P45592	intact:EBI-15348306|ensembl:ENSRNOP00000023037	intact:EBI-917556|ensembl:ENSRNOP00000059624	psi-mi:itm2b_rat(display_long)|uniprotkb:Itm2b(gene name)|psi-mi:Itm2b(display_short)|uniprotkb:Immature BRI2(gene name synonym)|uniprotkb:Transmembrane protein BRI(gene name synonym)	psi-mi:cof1_rat(display_long)|uniprotkb:Cofilin, non-muscle isoform(gene name synonym)|uniprotkb:Cfl1(gene name)|psi-mi:Cfl1(display_short)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Martins et al. (2018)	imex:IM-28469|pubmed:29476059	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26438079|imex:IM-28469-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSRNOG00000016271(gene)|ensembl:ENSRNOT00000023037(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001540"(amyloid-beta binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0010008"(endosome membrane)|go:"GO:0030660"(Golgi-associated vesicle membrane)|go:"GO:0031301"(integral component of organelle membrane)|go:"GO:0042985"(negative regulation of amyloid precursor protein biosynthetic process)|interpro:IPR007084(BRICHOS)|interpro:IPR040145|mint:Q5XIE8|refseq:NP_001006964.1|rgd:620727	rgd:69285|refseq:NP_058843.1|ensembl:ENSRNOG00000020660(gene)|ensembl:ENSRNOT00000015962(transcript)|go:"GO:0000281"(mitotic cytokinesis)|go:"GO:0001755"(neural crest cell migration)|go:"GO:0001842"(neural fold formation)|go:"GO:0003779"(actin binding)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005925"(focal adhesion)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0007010"(cytoskeleton organization)|go:"GO:0007015"(actin filament organization)|go:"GO:0007162"(negative regulation of cell adhesion)|go:"GO:0009615"(response to virus)|go:"GO:0010592"(positive regulation of lamellipodium assembly)|go:"GO:0010593"(negative regulation of lamellipodium assembly)|go:"GO:0014070"(response to organic cyclic compound)|go:"GO:0014823"(response to activity)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0016363"(nuclear matrix)|go:"GO:0019903"(protein phosphatase binding)|go:"GO:0021766"(hippocampus development)|go:"GO:0022604"(regulation of cell morphogenesis)|go:"GO:0030010"(establishment of cell polarity)|go:"GO:0030027"(lamellipodium)|go:"GO:0030030"(cell projection organization)|go:"GO:0030042"(actin filament depolymerization)|go:"GO:0030043"(actin filament fragmentation)|go:"GO:0030175"(filopodium)|go:"GO:0030307"(positive regulation of cell growth)|go:"GO:0030426"(growth cone)|go:"GO:0030835"(negative regulation of actin filament depolymerization)|go:"GO:0030836"(positive regulation of actin filament depolymerization)|go:"GO:0030864"(cortical actin cytoskeleton)|go:"GO:0031252"(cell leading edge)|go:"GO:0031258"(lamellipodium membrane)|go:"GO:0031915"(positive regulation of synaptic plasticity)|go:"GO:0031966"(mitochondrial membrane)|go:"GO:0032232"(negative regulation of actin filament bundle assembly)|go:"GO:0032587"(ruffle membrane)|go:"GO:0040019"(positive regulation of embryonic development)|go:"GO:0043005"(neuron projection)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043197"(dendritic spine)|go:"GO:0043200"(response to amino acid)|go:"GO:0044794"(positive regulation by host of viral process)|go:"GO:0045792"(negative regulation of cell size)|go:"GO:0045862"(positive regulation of proteolysis)|go:"GO:0048870"(cell motility)|go:"GO:0051014"(actin filament severing)|go:"GO:0051015"(actin filament binding)|go:"GO:0051293"(establishment of spindle localization)|go:"GO:0051511"(negative regulation of unidimensional cell growth)|go:"GO:0051894"(positive regulation of focal adhesion assembly)|go:"GO:0060999"(positive regulation of dendritic spine development)|go:"GO:0061001"(regulation of dendritic spine morphogenesis)|go:"GO:0070301"(cellular response to hydrogen peroxide)|go:"GO:0071347"(cellular response to interleukin-1)|go:"GO:0071354"(cellular response to interleukin-6)|go:"GO:0071356"(cellular response to tumor necrosis factor)|go:"GO:0071362"(cellular response to ether)|go:"GO:0071364"(cellular response to epidermal growth factor stimulus)|go:"GO:0090732"(cofilin-actin rod)|go:"GO:0097060"(synaptic membrane)|go:"GO:0098885"(modification of postsynaptic actin cytoskeleton)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:1902936"(phosphatidylinositol bisphosphate binding)|go:"GO:1902951"(negative regulation of dendritic spine maintenance)|go:"GO:1904783"(positive regulation of NMDA glutamate receptor activity)|go:"GO:1905873"(positive regulation of protein localization to cell leading edge)|go:"GO:1905875"(negative regulation of postsynaptic density organization)|go:"GO:1990314"(cellular response to insulin-like growth factor stimulus)|go:"GO:2000146"(negative regulation of cell motility)|go:"GO:2000147"(positive regulation of cell motility)|go:"GO:2000784"(positive regulation of establishment of cell polarity regulating cell shape)|go:"GO:2000814"(positive regulation of barbed-end actin filament capping)|interpro:IPR002108(Actin-binding, cofilin/tropomyosin type)|interpro:IPR017904|interpro:IPR027234|interpro:IPR029006|mint:P45592	-	-	-	figure legend:ST1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10116(rat-brain-cerebellum)|taxid:10116(Rattus norvegicus)	-	2020/10/30	2020/10/30	rogid:DtE+ZXAZKdCMvUW5K+jXQ5bH07M10116	rogid:xwFEqVHm0stGEHpMoijBFH/LwPY10116	rigid:OaXQ9NA25fwCWxejPU3Ao9q5j/E	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q5XIE8	uniprotkb:P40241	intact:EBI-15348306|ensembl:ENSRNOP00000023037	intact:EBI-26437684|ensembl:ENSRNOP00000026633	psi-mi:itm2b_rat(display_long)|uniprotkb:Itm2b(gene name)|psi-mi:Itm2b(display_short)|uniprotkb:Immature BRI2(gene name synonym)|uniprotkb:Transmembrane protein BRI(gene name synonym)	psi-mi:cd9_rat(display_long)|uniprotkb:Cd9(gene name)|psi-mi:Cd9(display_short)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Martins et al. (2018)	imex:IM-28469|pubmed:29476059	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26438079|imex:IM-28469-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSRNOG00000016271(gene)|ensembl:ENSRNOT00000023037(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001540"(amyloid-beta binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0010008"(endosome membrane)|go:"GO:0030660"(Golgi-associated vesicle membrane)|go:"GO:0031301"(integral component of organelle membrane)|go:"GO:0042985"(negative regulation of amyloid precursor protein biosynthetic process)|interpro:IPR007084(BRICHOS)|interpro:IPR040145|mint:Q5XIE8|refseq:NP_001006964.1|rgd:620727	reactome:R-RNO-1300645|ensembl:ENSRNOG00000019556(gene)|ensembl:ENSRNOT00000026633(transcript)|go:"GO:0005178"(integrin binding)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0007338"(single fertilization)|go:"GO:0007342"(fusion of sperm to egg plasma membrane involved in single fertilization)|go:"GO:0007420"(brain development)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0008347"(glial cell migration)|go:"GO:0009414"(response to water deprivation)|go:"GO:0009897"(external side of plasma membrane)|go:"GO:0009986"(cell surface)|go:"GO:0014003"(oligodendrocyte development)|go:"GO:0014905"(myoblast fusion involved in skeletal muscle regeneration)|go:"GO:0016020"(membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0030913"(paranodal junction assembly)|go:"GO:0031623"(receptor internalization)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035036"(sperm-egg recognition)|go:"GO:0051271"(negative regulation of cellular component movement)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071404"(cellular response to low-density lipoprotein particle stimulus)|go:"GO:0090331"(negative regulation of platelet aggregation)|go:"GO:1905521"(regulation of macrophage migration)|interpro:IPR000301(CD9/CD37/CD63 antigen)|interpro:IPR008952(Tetraspanin)|interpro:IPR018499|interpro:IPR018503|interpro:IPR042055|mint:P40241|reactome:R-RNO-114608|go:"GO:0007155"(cell adhesion)|refseq:NP_444177.1|rgd:2318	-	-	-	figure legend:ST1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10116(rat-brain-cerebellum)|taxid:10116(Rattus norvegicus)	-	2020/10/30	2020/10/30	rogid:DtE+ZXAZKdCMvUW5K+jXQ5bH07M10116	rogid:UagE7Mr3lqoy8A7VYuUSd+UezKc10116	rigid:OaXQ9NA25fwCWxejPU3Ao9q5j/E	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q5XIE8	uniprotkb:P19139	intact:EBI-15348306|ensembl:ENSRNOP00000023037	intact:EBI-1373494|uniprotkb:Q5BKC1|ensembl:ENSRNOP00000007558	psi-mi:itm2b_rat(display_long)|uniprotkb:Itm2b(gene name)|psi-mi:Itm2b(display_short)|uniprotkb:Immature BRI2(gene name synonym)|uniprotkb:Transmembrane protein BRI(gene name synonym)	psi-mi:csk21_rat(display_long)|uniprotkb:Csnk2a1(gene name)|psi-mi:Csnk2a1(display_short)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Martins et al. (2018)	imex:IM-28469|pubmed:29476059	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26438079|imex:IM-28469-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSRNOG00000016271(gene)|ensembl:ENSRNOT00000023037(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001540"(amyloid-beta binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0010008"(endosome membrane)|go:"GO:0030660"(Golgi-associated vesicle membrane)|go:"GO:0031301"(integral component of organelle membrane)|go:"GO:0042985"(negative regulation of amyloid precursor protein biosynthetic process)|interpro:IPR007084(BRICHOS)|interpro:IPR040145|mint:Q5XIE8|refseq:NP_001006964.1|rgd:620727	rgd:621663|refseq:NP_446276.1|refseq:XP_006235282.1|refseq:XP_006235283.1|reactome:R-RNO-6804756|reactome:R-RNO-6814122|reactome:R-RNO-8934903|reactome:R-RNO-8939243|reactome:R-RNO-8948751|ensembl:ENSRNOG00000005276(gene)|ensembl:ENSRNOT00000007558(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005956"(protein kinase CK2 complex)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0006915"(apoptotic process)|go:"GO:0007049"(cell cycle)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0016301"(kinase activity)|go:"GO:0016580"(Sin3 complex)|go:"GO:0016581"(NuRD complex)|go:"GO:0018105"(peptidyl-serine phosphorylation)|go:"GO:0018107"(peptidyl-threonine phosphorylation)|go:"GO:0019888"(protein phosphatase regulator activity)|go:"GO:0021987"(cerebral cortex development)|go:"GO:0030177"(positive regulation of Wnt signaling pathway)|go:"GO:0030307"(positive regulation of cell growth)|go:"GO:0033574"(response to testosterone)|go:"GO:0042802"(identical protein binding)|go:"GO:0043021"(ribonucleoprotein complex binding)|go:"GO:0043154"(negative regulation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0045732"(positive regulation of protein catabolic process)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0047485"(protein N-terminus binding)|go:"GO:0048511"(rhythmic process)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0097421"(liver regeneration)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:1903076"(regulation of protein localization to plasma membrane)|go:"GO:1905818"(regulation of chromosome separation)|go:"GO:2000059"(negative regulation of ubiquitin-dependent protein catabolic process)|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|mint:P19139|rcsb pdb:2R7I|reactome:R-RNO-1483191|reactome:R-RNO-201688|reactome:R-RNO-2514853|reactome:R-RNO-445144	-	-	-	figure legend:ST1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10116(rat-brain-cerebellum)|taxid:10116(Rattus norvegicus)	-	2020/10/30	2020/10/30	rogid:DtE+ZXAZKdCMvUW5K+jXQ5bH07M10116	rogid:igJEbVxBh30nMZF6jfiISzpHEMQ10116	rigid:OaXQ9NA25fwCWxejPU3Ao9q5j/E	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q5XIE8	uniprotkb:Q9ESS6	intact:EBI-15348306|ensembl:ENSRNOP00000023037	intact:EBI-26437661|ensembl:ENSRNOP00000047809	psi-mi:itm2b_rat(display_long)|uniprotkb:Itm2b(gene name)|psi-mi:Itm2b(display_short)|uniprotkb:Immature BRI2(gene name synonym)|uniprotkb:Transmembrane protein BRI(gene name synonym)	psi-mi:bcam_rat(display_long)|uniprotkb:Bcam(gene name)|psi-mi:Bcam(display_short)|uniprotkb:Lu(gene name synonym)|uniprotkb:B-CAM cell surface glycoprotein(gene name synonym)|uniprotkb:Lutheran antigen(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Martins et al. (2018)	imex:IM-28469|pubmed:29476059	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26438079|imex:IM-28469-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSRNOG00000016271(gene)|ensembl:ENSRNOT00000023037(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001540"(amyloid-beta binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0010008"(endosome membrane)|go:"GO:0030660"(Golgi-associated vesicle membrane)|go:"GO:0031301"(integral component of organelle membrane)|go:"GO:0042985"(negative regulation of amyloid precursor protein biosynthetic process)|interpro:IPR007084(BRICHOS)|interpro:IPR040145|mint:Q5XIE8|refseq:NP_001006964.1|rgd:620727	ensembl:ENSRNOG00000029399(gene)|ensembl:ENSRNOT00000045574(transcript)|go:"GO:0005055"(laminin receptor activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0007155"(cell adhesion)|go:"GO:0007160"(cell-matrix adhesion)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0009986"(cell surface)|go:"GO:0016021"(integral component of membrane)|go:"GO:0043236"(laminin binding)|interpro:IPR003598(Immunoglobulin subtype 2)|interpro:IPR003599(Immunoglobulin subtype)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR013162(CD80-like, immunoglobulin C2-set)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR036179|mint:Q9ESS6|refseq:NP_113940.1|rgd:68378	-	-	-	figure legend:ST1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10116(rat-brain-cerebellum)|taxid:10116(Rattus norvegicus)	-	2020/10/30	2020/10/30	rogid:DtE+ZXAZKdCMvUW5K+jXQ5bH07M10116	rogid:gXifukdZ+aemcGCwqz/Q8qlsqBo10116	rigid:OaXQ9NA25fwCWxejPU3Ao9q5j/E	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q5XIE8	uniprotkb:Q9WTP0	intact:EBI-15348306|ensembl:ENSRNOP00000023037	intact:EBI-11169976|uniprotkb:Q9WTP1	psi-mi:itm2b_rat(display_long)|uniprotkb:Itm2b(gene name)|psi-mi:Itm2b(display_short)|uniprotkb:Immature BRI2(gene name synonym)|uniprotkb:Transmembrane protein BRI(gene name synonym)	psi-mi:e41l1_rat(display_long)|uniprotkb:Epb41l1(gene name)|psi-mi:Epb41l1(display_short)|uniprotkb:Epb4.1l1(gene name synonym)|uniprotkb:Neuronal protein 4.1(gene name synonym)|uniprotkb:Erythrocyte membrane protein band 4.1-like 1(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Martins et al. (2018)	imex:IM-28469|pubmed:29476059	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26438079|imex:IM-28469-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSRNOG00000016271(gene)|ensembl:ENSRNOT00000023037(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001540"(amyloid-beta binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0010008"(endosome membrane)|go:"GO:0030660"(Golgi-associated vesicle membrane)|go:"GO:0031301"(integral component of organelle membrane)|go:"GO:0042985"(negative regulation of amyloid precursor protein biosynthetic process)|interpro:IPR007084(BRICHOS)|interpro:IPR040145|mint:Q5XIE8|refseq:NP_001006964.1|rgd:620727	refseq:NP_742087.1|interpro:IPR008379(Band 4.1, C-terminal)|interpro:IPR019749|interpro:IPR000798(Ezrin/radixin/moesin ERM)|interpro:IPR014847("FERM adjacent (FA)")|interpro:IPR014352(FERM/acyl-CoA-binding protein, 3-helical bundle)|interpro:IPR019748|interpro:IPR019747|interpro:IPR000299(Band 4.1, N-terminal)|interpro:IPR018979|interpro:IPR018980|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR007477(SAB)|interpro:IPR029071|rgd:71087|go:"GO:0003779"(actin binding)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005886"(plasma membrane)|go:"GO:0014069"(postsynaptic density)|go:"GO:0030866"(cortical actin cytoskeleton organization)|go:"GO:0031032"(actomyosin structure organization)|go:"GO:0032991"(protein-containing complex)|go:"GO:0097060"(synaptic membrane)|reactome:R-RNO-399719|reactome:R-RNO-6794361|mint:Q9WTP0|interpro:IPR035963	-	-	-	figure legend:ST1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10116(rat-brain-cerebellum)|taxid:10116(Rattus norvegicus)	-	2020/10/30	2020/10/30	rogid:DtE+ZXAZKdCMvUW5K+jXQ5bH07M10116	rogid:UEt+cCxW/3aDNyIqQUHiCHjI4K410116	rigid:OaXQ9NA25fwCWxejPU3Ao9q5j/E	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q5XIE8	uniprotkb:Q06647	intact:EBI-15348306|ensembl:ENSRNOP00000023037	intact:EBI-918179|ensembl:ENSRNOP00000002732	psi-mi:itm2b_rat(display_long)|uniprotkb:Itm2b(gene name)|psi-mi:Itm2b(display_short)|uniprotkb:Immature BRI2(gene name synonym)|uniprotkb:Transmembrane protein BRI(gene name synonym)	psi-mi:atpo_rat(display_long)|uniprotkb:Atp5po(gene name)|psi-mi:Atp5po(display_short)|uniprotkb:ATP synthase peripheral stalk subunit OSCP(gene name synonym)|uniprotkb:Atp5o(gene name synonym)|uniprotkb:Oligomycin sensitivity conferral protein(gene name synonym)|uniprotkb:Sperm flagella protein 4(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Martins et al. (2018)	imex:IM-28469|pubmed:29476059	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26438079|imex:IM-28469-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSRNOG00000016271(gene)|ensembl:ENSRNOT00000023037(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001540"(amyloid-beta binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0010008"(endosome membrane)|go:"GO:0030660"(Golgi-associated vesicle membrane)|go:"GO:0031301"(integral component of organelle membrane)|go:"GO:0042985"(negative regulation of amyloid precursor protein biosynthetic process)|interpro:IPR007084(BRICHOS)|interpro:IPR040145|mint:Q5XIE8|refseq:NP_001006964.1|rgd:620727	rgd:621379|refseq:NP_620238.1|ensembl:ENSRNOG00000001991(gene)|ensembl:ENSRNOT00000002732(transcript)|go:"GO:0000274"(mitochondrial proton-transporting ATP synthase, stator stalk)|go:"GO:0000276"("mitochondrial proton-transporting ATP synthase complex, coupling factor F(o)")|go:"GO:0005739"(mitochondrion)|go:"GO:0005753"(mitochondrial proton-transporting ATP synthase complex)|go:"GO:0005886"(plasma membrane)|go:"GO:0006754"(ATP biosynthetic process)|go:"GO:0009986"(cell surface)|go:"GO:0015986"(ATP synthesis coupled proton transport)|go:"GO:0042776"(mitochondrial ATP synthesis coupled proton transport)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045261"("proton-transporting ATP synthase complex, catalytic core F(1)")|go:"GO:0046034"(ATP metabolic process)|go:"GO:0046933"(proton-transporting ATP synthase activity, rotational mechanism)|go:"GO:0071320"(cellular response to cAMP)|go:"GO:0071345"(cellular response to cytokine stimulus)|go:"GO:1903924"(estradiol binding)|interpro:IPR000711(ATPase, F1 complex, OSCP/delta subunit)|interpro:IPR020781|interpro:IPR026015|mint:Q06647|reactome:R-RNO-163210|reactome:R-RNO-8949613	-	-	-	figure legend:ST1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10116(rat-brain-cerebellum)|taxid:10116(Rattus norvegicus)	-	2020/10/30	2020/10/30	rogid:DtE+ZXAZKdCMvUW5K+jXQ5bH07M10116	rogid:F/PihaxUf1uclL8LOwKpSse+dCA10116	rigid:OaXQ9NA25fwCWxejPU3Ao9q5j/E	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q5XIE8	uniprotkb:P35435	intact:EBI-15348306|ensembl:ENSRNOP00000023037	intact:EBI-917355	psi-mi:itm2b_rat(display_long)|uniprotkb:Itm2b(gene name)|psi-mi:Itm2b(display_short)|uniprotkb:Immature BRI2(gene name synonym)|uniprotkb:Transmembrane protein BRI(gene name synonym)	psi-mi:atpg_rat(display_long)|uniprotkb:Atp5f1c(gene name)|psi-mi:Atp5f1c(display_short)|uniprotkb:ATP synthase F1 subunit gamma(gene name synonym)|uniprotkb:Atp5c(gene name synonym)|uniprotkb:Atp5c1(gene name synonym)|uniprotkb:F-ATPase gamma subunit(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Martins et al. (2018)	imex:IM-28469|pubmed:29476059	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26438079|imex:IM-28469-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSRNOG00000016271(gene)|ensembl:ENSRNOT00000023037(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001540"(amyloid-beta binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0010008"(endosome membrane)|go:"GO:0030660"(Golgi-associated vesicle membrane)|go:"GO:0031301"(integral component of organelle membrane)|go:"GO:0042985"(negative regulation of amyloid precursor protein biosynthetic process)|interpro:IPR007084(BRICHOS)|interpro:IPR040145|mint:Q5XIE8|refseq:NP_001006964.1|rgd:620727	rgd:620011|interpro:IPR000131(ATPase, F1 complex, gamma subunit)|interpro:IPR023632|mint:P35435|interpro:IPR035968|go:"GO:0000275"("mitochondrial proton-transporting ATP synthase complex, catalytic sector F(1)")|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005753"(mitochondrial proton-transporting ATP synthase complex)|go:"GO:0015986"(ATP synthesis coupled proton transport)|go:"GO:0042776"(mitochondrial ATP synthesis coupled proton transport)|go:"GO:0045261"("proton-transporting ATP synthase complex, catalytic core F(1)")|go:"GO:0046034"(ATP metabolic process)|go:"GO:0046933"(proton-transporting ATP synthase activity, rotational mechanism)|go:"GO:0071732"(cellular response to nitric oxide)|rcsb pdb:1MAB|rcsb pdb:2F43|reactome:R-RNO-163210|reactome:R-RNO-8949613	-	-	-	figure legend:ST1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10116(rat-brain-cerebellum)|taxid:10116(Rattus norvegicus)	-	2020/10/30	2020/10/30	rogid:DtE+ZXAZKdCMvUW5K+jXQ5bH07M10116	rogid:py9RCXV2/aoMy8UslZteKeJAdak10116	rigid:OaXQ9NA25fwCWxejPU3Ao9q5j/E	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q5XIE8	uniprotkb:P18484	intact:EBI-15348306|ensembl:ENSRNOP00000023037	intact:EBI-539360	psi-mi:itm2b_rat(display_long)|uniprotkb:Itm2b(gene name)|psi-mi:Itm2b(display_short)|uniprotkb:Immature BRI2(gene name synonym)|uniprotkb:Transmembrane protein BRI(gene name synonym)	psi-mi:ap2a2_rat(display_long)|uniprotkb:Adaptor protein complex AP-2 subunit alpha-2(gene name synonym)|uniprotkb:Alpha2-adaptin(gene name synonym)|uniprotkb:Plasma membrane adaptor HA2/AP2 adaptin alpha C subunit(gene name synonym)|uniprotkb:Alpha-adaptin C(gene name synonym)|uniprotkb:Clathrin assembly protein complex 2 alpha-C large chain(gene name synonym)|uniprotkb:100 kDa coated vesicle protein C(gene name synonym)|uniprotkb:Ap2a2(gene name)|psi-mi:Ap2a2(display_short)|uniprotkb:Adtab(gene name synonym)|uniprotkb:Adaptor-related protein complex 2 subunit alpha-2(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Martins et al. (2018)	imex:IM-28469|pubmed:29476059	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26438079|imex:IM-28469-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSRNOG00000016271(gene)|ensembl:ENSRNOT00000023037(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001540"(amyloid-beta binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0010008"(endosome membrane)|go:"GO:0030660"(Golgi-associated vesicle membrane)|go:"GO:0031301"(integral component of organelle membrane)|go:"GO:0042985"(negative regulation of amyloid precursor protein biosynthetic process)|interpro:IPR007084(BRICHOS)|interpro:IPR040145|mint:Q5XIE8|refseq:NP_001006964.1|rgd:620727	rgd:71015|go:"GO:0005886"(plasma membrane)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006898"(receptor-mediated endocytosis)|interpro:IPR002553(Clathrin/coatomer adaptor, adaptin-like, N-terminal)|interpro:IPR003164(Clathrin adaptor, alpha-adaptin, appendage, C-terminal subdomain)|interpro:IPR008152(Clathrin adaptor, alpha/beta/gamma-adaptin, appendage, Ig-like subdomain)|interpro:IPR009028(Clathrin/coatomer adaptor, adaptin-like, appendage, C-terminal subdomain)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR012295(Beta2-adaptin/TATA-box binding, C-terminal)|interpro:IPR013041(Clathrin/coatomer adaptor, adaptin-like, appendage, Ig-like subdomain)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR017104(Adaptor protein complex AP-2, alpha subunit)|rcsb pdb:2VGL|rcsb pdb:2XA7|go:"GO:0008021"(synaptic vesicle)|rcsb pdb:4NEE|rcsb pdb:4UQI|rcsb pdb:6OWT|rcsb pdb:6QH5|rcsb pdb:6QH6|rcsb pdb:6QH7|go:"GO:0019900"(kinase binding)|rcsb pdb:6URI|rcsb pdb:6YAE|rcsb pdb:6YAF|rcsb pdb:6YAH|reactome:R-RNO-177504|reactome:R-RNO-2132295|reactome:R-RNO-416993|reactome:R-RNO-437239|reactome:R-RNO-5099900|reactome:R-RNO-5140745|reactome:R-RNO-6798695|reactome:R-RNO-8856825|go:"GO:0019901"(protein kinase binding)|reactome:R-RNO-8856828|go:"GO:0019904"(protein domain specific binding)|reactome:R-RNO-8866427|reactome:R-RNO-8964038|go:"GO:0030117"(membrane coat)|go:"GO:0030122"(AP-2 adaptor complex)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0035091"(phosphatidylinositol binding)|go:"GO:0035615"(clathrin adaptor activity)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0072583"(clathrin-dependent endocytosis)|go:"GO:0097718"(disordered domain specific binding)|go:"GO:0140312"(cargo adaptor activity)|mint:P18484|dip:DIP-29765N	-	-	-	figure legend:ST1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10116(rat-brain-cerebellum)|taxid:10116(Rattus norvegicus)	-	2020/10/30	2020/10/30	rogid:DtE+ZXAZKdCMvUW5K+jXQ5bH07M10116	rogid:/3UaX0n3j6Lo0w7GMn0uWzL5GI010116	rigid:OaXQ9NA25fwCWxejPU3Ao9q5j/E	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q5XIE8	uniprotkb:O70511	intact:EBI-15348306|ensembl:ENSRNOP00000023037	intact:EBI-9663355|uniprotkb:Q574D7|uniprotkb:Q574D8|uniprotkb:Q574D9|uniprotkb:Q574E0|uniprotkb:Q574E2|uniprotkb:Q8VDA0	psi-mi:itm2b_rat(display_long)|uniprotkb:Itm2b(gene name)|psi-mi:Itm2b(display_short)|uniprotkb:Immature BRI2(gene name synonym)|uniprotkb:Transmembrane protein BRI(gene name synonym)	psi-mi:ank3_rat(display_long)|uniprotkb:Ank3(gene name)|psi-mi:Ank3(display_short)|uniprotkb:Ankyrin-G(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Martins et al. (2018)	imex:IM-28469|pubmed:29476059	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26438079|imex:IM-28469-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSRNOG00000016271(gene)|ensembl:ENSRNOT00000023037(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001540"(amyloid-beta binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0010008"(endosome membrane)|go:"GO:0030660"(Golgi-associated vesicle membrane)|go:"GO:0031301"(integral component of organelle membrane)|go:"GO:0042985"(negative regulation of amyloid precursor protein biosynthetic process)|interpro:IPR007084(BRICHOS)|interpro:IPR040145|mint:Q5XIE8|refseq:NP_001006964.1|rgd:620727	mint:O70511|rgd:620157|refseq:NP_001029156.1|refseq:NP_113993.1|dip:DIP-60342N|go:"GO:0000281"(mitotic cytokinesis)|go:"GO:0005200"(structural constituent of cytoskeleton)|go:"GO:0005764"(lysosome)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005886"(plasma membrane)|go:"GO:0007009"(plasma membrane organization)|go:"GO:0007165"(signal transduction)|go:"GO:0007409"(axonogenesis)|go:"GO:0007411"(axon guidance)|go:"GO:0007528"(neuromuscular junction development)|go:"GO:0008092"(cytoskeletal protein binding)|go:"GO:0009925"(basal plasma membrane)|go:"GO:0009986"(cell surface)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010650"(positive regulation of cell communication by electrical coupling)|go:"GO:0010765"(positive regulation of sodium ion transport)|go:"GO:0010960"(magnesium ion homeostasis)|go:"GO:0014704"(intercalated disc)|go:"GO:0014731"(spectrin-associated cytoskeleton)|go:"GO:0016020"(membrane)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016328"(lateral plasma membrane)|go:"GO:0016529"(sarcoplasmic reticulum)|go:"GO:0019228"(neuronal action potential)|go:"GO:0030018"(Z disc)|go:"GO:0030315"(T-tubule)|go:"GO:0030424"(axon)|go:"GO:0030425"(dendrite)|go:"GO:0030507"(spectrin binding)|go:"GO:0030674"(protein-macromolecule adaptor activity)|go:"GO:0031594"(neuromuscular junction)|go:"GO:0033268"(node of Ranvier)|go:"GO:0033270"(paranode region of axon)|go:"GO:0034112"(positive regulation of homotypic cell-cell adhesion)|go:"GO:0042383"(sarcolemma)|go:"GO:0043001"(Golgi to plasma membrane protein transport)|go:"GO:0043005"(neuron projection)|go:"GO:0043034"(costamere)|go:"GO:0043266"(regulation of potassium ion transport)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0045162"(clustering of voltage-gated sodium channels)|go:"GO:0045184"(establishment of protein localization)|go:"GO:0045202"(synapse)|go:"GO:0045211"(postsynaptic membrane)|go:"GO:0045296"(cadherin binding)|go:"GO:0045838"(positive regulation of membrane potential)|go:"GO:0050808"(synapse organization)|go:"GO:0071286"(cellular response to magnesium ion)|go:"GO:0071709"(membrane assembly)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0072660"(maintenance of protein location in plasma membrane)|go:"GO:0090314"(positive regulation of protein targeting to membrane)|go:"GO:0099612"(protein localization to axon)|go:"GO:0140031"(phosphorylation-dependent protein binding)|go:"GO:1900827"(positive regulation of membrane depolarization during cardiac muscle cell action potential)|go:"GO:1902260"(negative regulation of delayed rectifier potassium channel activity)|go:"GO:2000651"(positive regulation of sodium ion transmembrane transporter activity)|go:"GO:2001259"(positive regulation of cation channel activity)|interpro:IPR000488(Death)|interpro:IPR000906(ZU5)|interpro:IPR002110(Ankyrin)|interpro:IPR011029(DEATH-like)|interpro:IPR020683|interpro:IPR036770|interpro:IPR037971|interpro:IPR040745|rcsb pdb:5YIP|rcsb pdb:5YIQ|rcsb pdb:6A9X|rcsb pdb:6M3P|rcsb pdb:6M3R|go:"GO:0043194"(axon initial segment)	-	-	-	figure legend:ST1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10116(rat-brain-cerebellum)|taxid:10116(Rattus norvegicus)	-	2020/10/30	2020/10/30	rogid:DtE+ZXAZKdCMvUW5K+jXQ5bH07M10116	rogid:FloqiVqbDqo4HEvTwKuGl7Q0Cxw10116	rigid:OaXQ9NA25fwCWxejPU3Ao9q5j/E	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q5XIE8	uniprotkb:O08838	intact:EBI-15348306|ensembl:ENSRNOP00000023037	intact:EBI-80080	psi-mi:itm2b_rat(display_long)|uniprotkb:Itm2b(gene name)|psi-mi:Itm2b(display_short)|uniprotkb:Immature BRI2(gene name synonym)|uniprotkb:Transmembrane protein BRI(gene name synonym)	psi-mi:amph_rat(display_long)|uniprotkb:Amph(gene name)|psi-mi:Amph(display_short)|uniprotkb:Amph1(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Martins et al. (2018)	imex:IM-28469|pubmed:29476059	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26438079|imex:IM-28469-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSRNOG00000016271(gene)|ensembl:ENSRNOT00000023037(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001540"(amyloid-beta binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0010008"(endosome membrane)|go:"GO:0030660"(Golgi-associated vesicle membrane)|go:"GO:0031301"(integral component of organelle membrane)|go:"GO:0042985"(negative regulation of amyloid precursor protein biosynthetic process)|interpro:IPR007084(BRICHOS)|interpro:IPR040145|mint:Q5XIE8|refseq:NP_001006964.1|rgd:620727	go:"GO:0045807"(positive regulation of endocytosis)|go:"GO:0048488"(synaptic vesicle endocytosis)|go:"GO:0005543"(phospholipid binding)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005886"(plasma membrane)|go:"GO:0007612"(learning)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0031256"(leading edge membrane)|go:"GO:0043195"(terminal bouton)|go:"GO:0043547"(positive regulation of GTPase activity)|go:"GO:0043679"(axon terminus)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0098684"(photoreceptor ribbon synapse)|go:"GO:0098793"(presynapse)|go:"GO:0098833"(presynaptic endocytic zone)|go:"GO:0098850"(extrinsic component of synaptic vesicle membrane)|go:"GO:0098978"(glutamatergic synapse)|interpro:IPR001452(Src homology-3)|interpro:IPR003005(Amphiphysin)|interpro:IPR003017(Amphiphysin, isoform 1)|interpro:IPR004148(BAR)|interpro:IPR027267|interpro:IPR035470|interpro:IPR036028|rcsb pdb:2VJ0|rcsb pdb:5M5T|reactome:R-RNO-8856828|rgd:620274|refseq:NP_071553.1|mint:O08838|dip:DIP-30977N	-	-	-	figure legend:ST1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10116(rat-brain-cerebellum)|taxid:10116(Rattus norvegicus)	-	2020/10/30	2020/10/30	rogid:DtE+ZXAZKdCMvUW5K+jXQ5bH07M10116	rogid:wTANhsy4BxCZYbSIhwlrr+m9Tt810116	rigid:OaXQ9NA25fwCWxejPU3Ao9q5j/E	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q5XIE8	uniprotkb:P23565	intact:EBI-15348306|ensembl:ENSRNOP00000023037	intact:EBI-6899875	psi-mi:itm2b_rat(display_long)|uniprotkb:Itm2b(gene name)|psi-mi:Itm2b(display_short)|uniprotkb:Immature BRI2(gene name synonym)|uniprotkb:Transmembrane protein BRI(gene name synonym)	psi-mi:ainx_rat(display_long)|uniprotkb:Ina(gene name)|psi-mi:Ina(display_short)|uniprotkb:Inexa(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Martins et al. (2018)	imex:IM-28469|pubmed:29476059	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26438079|imex:IM-28469-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSRNOG00000016271(gene)|ensembl:ENSRNOT00000023037(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001540"(amyloid-beta binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0010008"(endosome membrane)|go:"GO:0030660"(Golgi-associated vesicle membrane)|go:"GO:0031301"(integral component of organelle membrane)|go:"GO:0042985"(negative regulation of amyloid precursor protein biosynthetic process)|interpro:IPR007084(BRICHOS)|interpro:IPR040145|mint:Q5XIE8|refseq:NP_001006964.1|rgd:620727	go:"GO:0099160"(postsynaptic intermediate filament cytoskeleton)|go:"GO:0099184"(structural constituent of postsynaptic intermediate filament cytoskeleton)|go:"GO:1990830"(cellular response to leukemia inhibitory factor)|go:"GO:0005883"(neurofilament)|go:"GO:0007399"(nervous system development)|go:"GO:0030154"(cell differentiation)|go:"GO:0036464"(cytoplasmic ribonucleoprotein granule)|go:"GO:0042246"(tissue regeneration)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045104"(intermediate filament cytoskeleton organization)|go:"GO:0060052"(neurofilament cytoskeleton organization)|go:"GO:0098685"(Schaffer collateral - CA1 synapse)|go:"GO:0098794"(postsynapse)|go:"GO:0098973"(structural constituent of postsynaptic actin cytoskeleton)|go:"GO:0098978"(glutamatergic synapse)|interpro:IPR006821(Intermediate filament, DNA-binding region)|interpro:IPR018039|rgd:2911|mint:P23565|interpro:IPR027703|interpro:IPR039008	-	-	-	figure legend:ST1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10116(rat-brain-cerebellum)|taxid:10116(Rattus norvegicus)	-	2020/10/30	2020/10/30	rogid:DtE+ZXAZKdCMvUW5K+jXQ5bH07M10116	rogid:4qBkIm9ifAEYegj00H2EUgBCn0w10116	rigid:OaXQ9NA25fwCWxejPU3Ao9q5j/E	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q5XIE8	uniprotkb:P06238	intact:EBI-15348306|ensembl:ENSRNOP00000023037	intact:EBI-15184861|ensembl:ENSRNOP00000019346|ensembl:ENSRNOP00000066130|uniprotkb:Q4FZY3	psi-mi:itm2b_rat(display_long)|uniprotkb:Itm2b(gene name)|psi-mi:Itm2b(display_short)|uniprotkb:Immature BRI2(gene name synonym)|uniprotkb:Transmembrane protein BRI(gene name synonym)	psi-mi:a2mg_rat(display_long)|uniprotkb:A2m(gene name)|psi-mi:A2m(display_short)|uniprotkb:A2m1(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Martins et al. (2018)	imex:IM-28469|pubmed:29476059	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26438079|imex:IM-28469-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSRNOG00000016271(gene)|ensembl:ENSRNOT00000023037(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001540"(amyloid-beta binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0010008"(endosome membrane)|go:"GO:0030660"(Golgi-associated vesicle membrane)|go:"GO:0031301"(integral component of organelle membrane)|go:"GO:0042985"(negative regulation of amyloid precursor protein biosynthetic process)|interpro:IPR007084(BRICHOS)|interpro:IPR040145|mint:Q5XIE8|refseq:NP_001006964.1|rgd:620727	ensembl:ENSRNOG00000028896(gene)|ensembl:ENSRNOG00000045772(gene)|ensembl:ENSRNOT00000019346(transcript)|ensembl:ENSRNOT00000075799(transcript)|go:"GO:0001553"(luteinization)|go:"GO:0001869"(negative regulation of complement activation, lectin pathway)|go:"GO:0002020"(protease binding)|go:"GO:0002438"(acute inflammatory response to antigenic stimulus)|go:"GO:0004866"(endopeptidase inhibitor activity)|go:"GO:0004867"(serine-type endopeptidase inhibitor activity)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005615"(extracellular space)|go:"GO:0006953"(acute-phase response)|go:"GO:0007584"(response to nutrient)|interpro:IPR002890(Alpha-2-macroglobulin, N-terminal)|interpro:IPR008930(Terpenoid cylases/protein prenyltransferase alpha-alpha toroid)|interpro:IPR009048(Alpha-macroglobulin, receptor-binding)|interpro:IPR011625(Alpha-2-macroglobulin, N-terminal 2)|interpro:IPR011626(A-macroglobulin complement component)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR014756(Immunoglobulin E-set)|interpro:IPR019742|interpro:IPR036595|interpro:IPR040839|interpro:IPR041555|interpro:IPR041813|mint:P06238|reactome:R-RNO-114608|reactome:R-RNO-140837|reactome:R-RNO-1474228|reactome:R-RNO-8963896|interpro:IPR001599(Alpha-2-macroglobulin)|go:"GO:0010037"(response to carbon dioxide)|go:"GO:0010951"(negative regulation of endopeptidase activity)|go:"GO:0019838"(growth factor binding)|go:"GO:0019899"(enzyme binding)|go:"GO:0019959"(interleukin-8 binding)|go:"GO:0019966"(interleukin-1 binding)|go:"GO:0034695"(response to prostaglandin E)|go:"GO:0042802"(identical protein binding)|go:"GO:0043120"(tumor necrosis factor binding)|go:"GO:0048306"(calcium-dependent protein binding)|go:"GO:0048403"(brain-derived neurotrophic factor binding)|go:"GO:0048406"(nerve growth factor binding)|go:"GO:0048863"(stem cell differentiation)|go:"GO:0051384"(response to glucocorticoid)|go:"GO:1990402"(embryonic liver development)|go:"GO:0009611"(response to wounding)|refseq:NP_036620.2|refseq:XP_003749876.1|rgd:2004	-	-	-	figure legend:ST1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10116(rat-brain-cerebellum)|taxid:10116(Rattus norvegicus)	-	2020/10/30	2020/10/30	rogid:DtE+ZXAZKdCMvUW5K+jXQ5bH07M10116	rogid:MAZi2KkXU2jKuLSeqwT1dNJlrY010116	rigid:OaXQ9NA25fwCWxejPU3Ao9q5j/E	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q5XIE8	uniprotkb:P63269	intact:EBI-15348306|ensembl:ENSRNOP00000023037	intact:EBI-297811|uniprotkb:P12718|ensembl:ENSRNOP00000050322	psi-mi:itm2b_rat(display_long)|uniprotkb:Itm2b(gene name)|psi-mi:Itm2b(display_short)|uniprotkb:Immature BRI2(gene name synonym)|uniprotkb:Transmembrane protein BRI(gene name synonym)	psi-mi:acth_rat(display_long)|uniprotkb:Actg2(gene name)|psi-mi:Actg2(display_short)|uniprotkb:Acta3(gene name synonym)|uniprotkb:Actsg(gene name synonym)|uniprotkb:Smooth muscle gamma-actin(gene name synonym)|uniprotkb:Gamma-2-actin(gene name synonym)|uniprotkb:Alpha-actin-3(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Martins et al. (2018)	imex:IM-28469|pubmed:29476059	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26438079|imex:IM-28469-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSRNOG00000016271(gene)|ensembl:ENSRNOT00000023037(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001540"(amyloid-beta binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0010008"(endosome membrane)|go:"GO:0030660"(Golgi-associated vesicle membrane)|go:"GO:0031301"(integral component of organelle membrane)|go:"GO:0042985"(negative regulation of amyloid precursor protein biosynthetic process)|interpro:IPR007084(BRICHOS)|interpro:IPR040145|mint:Q5XIE8|refseq:NP_001006964.1|rgd:620727	ensembl:ENSRNOG00000029401(gene)|ensembl:ENSRNOT00000042699(transcript)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005869"(dynactin complex)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0014829"(vascular associated smooth muscle contraction)|go:"GO:0030027"(lamellipodium)|go:"GO:0030175"(filopodium)|go:"GO:0032982"(myosin filament)|go:"GO:0044297"(cell body)|go:"GO:0071944"(cell periphery)|go:"GO:0090131"(mesenchyme migration)|interpro:IPR004000(Actin/actin-like)|interpro:IPR004001(Actin, conserved site)|interpro:IPR020902|interpro:IPR043129|mint:P63269|reactome:R-RNO-445355|rgd:2027|refseq:NP_037025.1|refseq:XP_006236790.1	-	-	-	figure legend:ST1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10116(rat-brain-cerebellum)|taxid:10116(Rattus norvegicus)	-	2020/10/30	2020/10/30	rogid:DtE+ZXAZKdCMvUW5K+jXQ5bH07M10116	rogid:tp0JsXhrGsRl5i4Wg2dyaPGUPxA10116	rigid:OaXQ9NA25fwCWxejPU3Ao9q5j/E	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q5XIE8	uniprotkb:P60711	intact:EBI-15348306|ensembl:ENSRNOP00000023037	intact:EBI-349272|uniprotkb:Q64316|uniprotkb:P02570|uniprotkb:P70514|uniprotkb:P99021|uniprotkb:Q11211|ensembl:ENSRNOP00000044296	psi-mi:itm2b_rat(display_long)|uniprotkb:Itm2b(gene name)|psi-mi:Itm2b(display_short)|uniprotkb:Immature BRI2(gene name synonym)|uniprotkb:Transmembrane protein BRI(gene name synonym)	psi-mi:actb_rat(display_long)|uniprotkb:Actb(gene name)|psi-mi:Actb(display_short)|uniprotkb:Beta-actin(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Martins et al. (2018)	imex:IM-28469|pubmed:29476059	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26438079|imex:IM-28469-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSRNOG00000016271(gene)|ensembl:ENSRNOT00000023037(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001540"(amyloid-beta binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0010008"(endosome membrane)|go:"GO:0030660"(Golgi-associated vesicle membrane)|go:"GO:0031301"(integral component of organelle membrane)|go:"GO:0042985"(negative regulation of amyloid precursor protein biosynthetic process)|interpro:IPR007084(BRICHOS)|interpro:IPR040145|mint:Q5XIE8|refseq:NP_001006964.1|rgd:620727	rgd:628837|refseq:NP_112406.1|ensembl:ENSRNOG00000034254(gene)|ensembl:ENSRNOT00000042459(transcript)|go:"GO:0000079"(regulation of cyclin-dependent protein serine/threonine kinase activity)|go:"GO:0001725"(stress fiber)|go:"GO:0001738"(morphogenesis of a polarized epithelium)|go:"GO:0002102"(podosome)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005884"(actin filament)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005912"(adherens junction)|go:"GO:0005925"(focal adhesion)|go:"GO:0007163"(establishment or maintenance of cell polarity)|go:"GO:0007409"(axonogenesis)|go:"GO:0007623"(circadian rhythm)|go:"GO:0009612"(response to mechanical stimulus)|go:"GO:0014069"(postsynaptic density)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0016020"(membrane)|go:"GO:0019894"(kinesin binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0022898"(regulation of transmembrane transporter activity)|go:"GO:0030027"(lamellipodium)|go:"GO:0030424"(axon)|go:"GO:0030863"(cortical cytoskeleton)|go:"GO:0030957"(Tat protein binding)|go:"GO:0032091"(negative regulation of protein binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034333"(adherens junction assembly)|go:"GO:0035902"(response to immobilization stress)|go:"GO:0036464"(cytoplasmic ribonucleoprotein granule)|go:"GO:0042802"(identical protein binding)|go:"GO:0043296"(apical junction complex)|go:"GO:0044305"(calyx of Held)|go:"GO:0045121"(membrane raft)|go:"GO:0045176"(apical protein localization)|go:"GO:0045202"(synapse)|go:"GO:0048488"(synaptic vesicle endocytosis)|go:"GO:0048870"(cell motility)|go:"GO:0050998"(nitric-oxide synthase binding)|go:"GO:0051621"(regulation of norepinephrine uptake)|go:"GO:0060041"(retina development in camera-type eye)|go:"GO:0070160"(tight junction)|go:"GO:0071257"(cellular response to electrical stimulus)|go:"GO:0071896"(protein localization to adherens junction)|go:"GO:0072749"(cellular response to cytochalasin B)|go:"GO:0097433"(dense body)|go:"GO:0098685"(Schaffer collateral - CA1 synapse)|go:"GO:0098871"(postsynaptic actin cytoskeleton)|go:"GO:0035267"(NuA4 histone acetyltransferase complex)|go:"GO:0098973"(structural constituent of postsynaptic actin cytoskeleton)|reactome:R-RNO-190873|reactome:R-RNO-196025|go:"GO:0098974"(postsynaptic actin cytoskeleton organization)|reactome:R-RNO-2029482|reactome:R-RNO-3928662|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0150111"(regulation of transepithelial transport)|reactome:R-RNO-418990|reactome:R-RNO-437239|go:"GO:1903076"(regulation of protein localization to plasma membrane)|reactome:R-RNO-4420097|reactome:R-RNO-445095|reactome:R-RNO-446353|reactome:R-RNO-5250924|reactome:R-RNO-5626467|reactome:R-RNO-5663213|reactome:R-RNO-5663220|reactome:R-RNO-5674135|reactome:R-RNO-5689603|reactome:R-RNO-5696394|reactome:R-RNO-8856828|reactome:R-RNO-9035034|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR004000(Actin/actin-like)|interpro:IPR004001(Actin, conserved site)|interpro:IPR020902|interpro:IPR043129|mint:P60711	-	-	-	figure legend:ST1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10116(rat-brain-cerebellum)|taxid:10116(Rattus norvegicus)	-	2020/10/30	2020/10/30	rogid:DtE+ZXAZKdCMvUW5K+jXQ5bH07M10116	rogid:Hoge1B8Pn56kvbNTpkSLsQuHwRc10116	rigid:OaXQ9NA25fwCWxejPU3Ao9q5j/E	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q5XIE8	uniprotkb:P06761	intact:EBI-15348306|ensembl:ENSRNOP00000023037	intact:EBI-916036|ensembl:ENSRNOP00000025064	psi-mi:itm2b_rat(display_long)|uniprotkb:Itm2b(gene name)|psi-mi:Itm2b(display_short)|uniprotkb:Immature BRI2(gene name synonym)|uniprotkb:Transmembrane protein BRI(gene name synonym)	psi-mi:bip_rat(display_long)|uniprotkb:Hspa5(gene name)|psi-mi:Hspa5(display_short)|uniprotkb:Grp78(gene name synonym)|uniprotkb:Immunoglobulin heavy chain-binding protein(gene name synonym)|uniprotkb:Steroidogenesis-activator polypeptide(gene name synonym)|uniprotkb:78 kDa glucose-regulated protein(gene name synonym)|uniprotkb:Binding-immunoglobulin protein(gene name synonym)|uniprotkb:Heat shock protein 70 family protein 5(gene name synonym)|uniprotkb:Heat shock protein family A member 5(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Martins et al. (2018)	imex:IM-28469|pubmed:29476059	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26438079|imex:IM-28469-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSRNOG00000016271(gene)|ensembl:ENSRNOT00000023037(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001540"(amyloid-beta binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0010008"(endosome membrane)|go:"GO:0030660"(Golgi-associated vesicle membrane)|go:"GO:0031301"(integral component of organelle membrane)|go:"GO:0042985"(negative regulation of amyloid precursor protein biosynthetic process)|interpro:IPR007084(BRICHOS)|interpro:IPR040145|mint:Q5XIE8|refseq:NP_001006964.1|rgd:620727	rgd:2843|refseq:NP_037215.1|ensembl:ENSRNOG00000018294(gene)|ensembl:ENSRNOT00000025067(transcript)|go:"GO:0001554"(luteolysis)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005788"(endoplasmic reticulum lumen)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005790"(smooth endoplasmic reticulum)|go:"GO:0005793"(endoplasmic reticulum-Golgi intermediate compartment)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006983"(ER overload response)|go:"GO:0008180"(COP9 signalosome)|go:"GO:0009314"(response to radiation)|go:"GO:0009986"(cell surface)|go:"GO:0010976"(positive regulation of neuron projection development)|go:"GO:0016020"(membrane)|go:"GO:0019899"(enzyme binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0021589"(cerebellum structural organization)|go:"GO:0021680"(cerebellar Purkinje cell layer development)|go:"GO:0030176"(integral component of endoplasmic reticulum membrane)|go:"GO:0030182"(neuron differentiation)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0030433"(ubiquitin-dependent ERAD pathway)|go:"GO:0030496"(midbody)|go:"GO:0030512"(negative regulation of transforming growth factor beta receptor signaling pathway)|go:"GO:0030968"(endoplasmic reticulum unfolded protein response)|go:"GO:0031072"(heat shock protein binding)|go:"GO:0031204"(posttranslational protein targeting to membrane, translocation)|go:"GO:0031333"(negative regulation of protein-containing complex assembly)|go:"GO:0031398"(positive regulation of protein ubiquitination)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034620"(cellular response to unfolded protein)|go:"GO:0034663"(endoplasmic reticulum chaperone complex)|go:"GO:0034976"(response to endoplasmic reticulum stress)|go:"GO:0035437"(maintenance of protein localization in endoplasmic reticulum)|go:"GO:0035690"|go:"GO:0036498"(IRE1-mediated unfolded protein response)|go:"GO:0042026"(protein refolding)|go:"GO:0042149"(cellular response to glucose starvation)|go:"GO:0042220"(response to cocaine)|go:"GO:0043022"(ribosome binding)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0044183"(protein folding chaperone)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0051085"(chaperone cofactor-dependent protein refolding)|go:"GO:0051402"(neuron apoptotic process)|go:"GO:0051603"(proteolysis involved in cellular protein catabolic process)|go:"GO:0051787"(misfolded protein binding)|go:"GO:0071236"(cellular response to antibiotic)|go:"GO:0071277"(cellular response to calcium ion)|go:"GO:0071287"(cellular response to manganese ion)|go:"GO:0071320"(cellular response to cAMP)|go:"GO:0071353"(cellular response to interleukin-4)|go:"GO:0071480"(cellular response to gamma radiation)|go:"GO:0097501"(stress response to metal ion)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|go:"GO:1901998"(toxin transport)|go:"GO:1903895"(negative regulation of IRE1-mediated unfolded protein response)|go:"GO:1904313"(response to methamphetamine hydrochloride)|go:"GO:1990090"(cellular response to nerve growth factor stimulus)|interpro:IPR013126(Heat shock protein 70)|interpro:IPR018181|interpro:IPR029047|interpro:IPR029048|interpro:IPR042050|interpro:IPR043129|mint:P06761|reactome:R-RNO-3371453|reactome:R-RNO-983170	-	-	-	figure legend:ST1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10116(rat-brain-cerebellum)|taxid:10116(Rattus norvegicus)	-	2020/10/30	2020/10/30	rogid:DtE+ZXAZKdCMvUW5K+jXQ5bH07M10116	rogid:5HRXkoNHYJvBA2iejRqltGRdJDw10116	rigid:OaXQ9NA25fwCWxejPU3Ao9q5j/E	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q5XIE8	uniprotkb:P62909	intact:EBI-15348306|ensembl:ENSRNOP00000023037	intact:EBI-432553|uniprotkb:P17073|uniprotkb:P47933|ensembl:ENSRNOP00000023935	psi-mi:itm2b_rat(display_long)|uniprotkb:Itm2b(gene name)|psi-mi:Itm2b(display_short)|uniprotkb:Immature BRI2(gene name synonym)|uniprotkb:Transmembrane protein BRI(gene name synonym)	psi-mi:rs3_rat(display_long)|uniprotkb:Rps3(gene name)|psi-mi:Rps3(display_short)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Martins et al. (2018)	imex:IM-28469|pubmed:29476059	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26438079|imex:IM-28469-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSRNOG00000016271(gene)|ensembl:ENSRNOT00000023037(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001540"(amyloid-beta binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0010008"(endosome membrane)|go:"GO:0030660"(Golgi-associated vesicle membrane)|go:"GO:0031301"(integral component of organelle membrane)|go:"GO:0042985"(negative regulation of amyloid precursor protein biosynthetic process)|interpro:IPR007084(BRICHOS)|interpro:IPR040145|mint:Q5XIE8|refseq:NP_001006964.1|rgd:620727	rgd:619888|refseq:NP_001009239.1|ensembl:ENSRNOG00000017418(gene)|ensembl:ENSRNOT00000023935(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0003684"(damaged DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0003906"("DNA-(apurinic or apyrimidinic site) endonuclease activity")|go:"GO:0004520"(endodeoxyribonuclease activity)|go:"GO:0005634"(nucleus)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0005829"(cytosol)|go:"GO:0005840"(ribosome)|go:"GO:0005844"(polysome)|go:"GO:0005886"(plasma membrane)|go:"GO:0006281"(DNA repair)|go:"GO:0006412"(translation)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0006915"(apoptotic process)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0007059"(chromosome segregation)|go:"GO:0008017"(microtubule binding)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0012505"(endomembrane system)|go:"GO:0014069"(postsynaptic density)|go:"GO:0015631"(tubulin binding)|go:"GO:0017148"(negative regulation of translation)|go:"GO:0019899"(enzyme binding)|go:"GO:0019900"(kinase binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0022626"(cytosolic ribosome)|go:"GO:0022627"(cytosolic small ribosomal subunit)|go:"GO:0030425"(dendrite)|go:"GO:0030544"(Hsp70 protein binding)|go:"GO:0031116"(positive regulation of microtubule polymerization)|go:"GO:0031334"(positive regulation of protein-containing complex assembly)|go:"GO:0031397"(negative regulation of protein ubiquitination)|go:"GO:0032079"(positive regulation of endodeoxyribonuclease activity)|go:"GO:0032357"(oxidized purine DNA binding)|go:"GO:0032358"(oxidized pyrimidine DNA binding)|go:"GO:0032587"(ruffle membrane)|go:"GO:0032743"(positive regulation of interleukin-2 production)|go:"GO:0034614"(cellular response to reactive oxygen species)|go:"GO:0042104"(positive regulation of activated T cell proliferation)|go:"GO:0042769"(obsolete DNA damage response, detection of DNA damage)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0043507"(positive regulation of JUN kinase activity)|go:"GO:0044390"(ubiquitin-like protein conjugating enzyme binding)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045202"(synapse)|go:"GO:0045738"(negative regulation of DNA repair)|go:"GO:0045739"(positive regulation of DNA repair)|go:"GO:0050862"(positive regulation of T cell receptor signaling pathway)|go:"GO:0051018"(protein kinase A binding)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|go:"GO:0051225"(spindle assembly)|go:"GO:0051301"(cell division)|go:"GO:0051879"(Hsp90 protein binding)|go:"GO:0061481"(response to TNF agonist)|go:"GO:0070181"(small ribosomal subunit rRNA binding)|go:"GO:0070301"(cellular response to hydrogen peroxide)|go:"GO:0071159"(NF-kappaB complex)|go:"GO:0071356"(cellular response to tumor necrosis factor)|go:"GO:0072686"(mitotic spindle)|go:"GO:0097100"(supercoiled DNA binding)|go:"GO:0140078"("class I DNA-(apurinic or apyrimidinic site) endonuclease activity")|go:"GO:1901224"(positive regulation of NIK/NF-kappaB signaling)|go:"GO:1902231"(positive regulation of intrinsic apoptotic signaling pathway in response to DNA damage)|go:"GO:1902546"(positive regulation of DNA N-glycosylase activity)|go:"GO:2001235"(positive regulation of apoptotic signaling pathway)|go:"GO:2001272"(positive regulation of cysteine-type endopeptidase activity involved in execution phase of apoptosis)|interpro:IPR001351(Ribosomal protein S3, C-terminal)|interpro:IPR004044(K Homology, type 2)|interpro:IPR005703(Ribosomal protein S3, eukaryotic/archaeal)|interpro:IPR009019(K Homology, prokaryotic type)|interpro:IPR015946(K homology-like, alpha/beta)|go:"GO:1905053"(positive regulation of base-excision repair)|go:"GO:1990090"(cellular response to nerve growth factor stimulus)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR018280|interpro:IPR036419|mint:P62909|reactome:R-RNO-156827|reactome:R-RNO-1799339|reactome:R-RNO-6791226|reactome:R-RNO-72649|reactome:R-RNO-72689|reactome:R-RNO-72695|reactome:R-RNO-72702|reactome:R-RNO-72706|reactome:R-RNO-975956|reactome:R-RNO-975957	-	-	-	figure legend:ST1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10116(rat-brain-cerebellum)|taxid:10116(Rattus norvegicus)	-	2020/10/30	2020/10/30	rogid:DtE+ZXAZKdCMvUW5K+jXQ5bH07M10116	rogid:f4Vh6HESE+lKZinjkJ883IG3wiY10116	rigid:OaXQ9NA25fwCWxejPU3Ao9q5j/E	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q5XIE8	uniprotkb:P86252	intact:EBI-15348306|ensembl:ENSRNOP00000023037	intact:EBI-1638520	psi-mi:itm2b_rat(display_long)|uniprotkb:Itm2b(gene name)|psi-mi:Itm2b(display_short)|uniprotkb:Immature BRI2(gene name synonym)|uniprotkb:Transmembrane protein BRI(gene name synonym)	psi-mi:pura_rat(display_long)|uniprotkb:Pura(gene name)|psi-mi:Pura(display_short)|uniprotkb:Purine-rich single-stranded DNA-binding protein alpha(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Martins et al. (2018)	imex:IM-28469|pubmed:29476059	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26438079|imex:IM-28469-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSRNOG00000016271(gene)|ensembl:ENSRNOT00000023037(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001540"(amyloid-beta binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0010008"(endosome membrane)|go:"GO:0030660"(Golgi-associated vesicle membrane)|go:"GO:0031301"(integral component of organelle membrane)|go:"GO:0042985"(negative regulation of amyloid precursor protein biosynthetic process)|interpro:IPR007084(BRICHOS)|interpro:IPR040145|mint:Q5XIE8|refseq:NP_001006964.1|rgd:620727	interpro:IPR006628(PUR-alpha/beta/gamma, DNA/RNA-binding)|rgd:1308543|mint:P86252|interpro:IPR030500|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000900"(translation repressor activity, mRNA regulatory element binding)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0003677"(DNA binding)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0003691"(double-stranded telomeric DNA binding)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006268"(DNA unwinding involved in DNA replication)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007399"(nervous system development)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0014069"(postsynaptic density)|go:"GO:0030154"(cell differentiation)|go:"GO:0030425"(dendrite)|go:"GO:0032422"(purine-rich negative regulatory element binding)|go:"GO:0032839"(dendrite cytoplasm)|go:"GO:0043025"(neuronal cell body)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0046332"(SMAD binding)|go:"GO:0046651"(lymphocyte proliferation)|go:"GO:0050673"(epithelial cell proliferation)|go:"GO:0098794"(postsynapse)|go:"GO:0098963"(dendritic transport of messenger ribonucleoprotein complex)|go:"GO:0098978"(glutamatergic synapse)	-	-	-	figure legend:ST1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10116(rat-brain-cerebellum)|taxid:10116(Rattus norvegicus)	-	2020/10/30	2020/10/30	rogid:DtE+ZXAZKdCMvUW5K+jXQ5bH07M10116	rogid:S+5CDoCwS0nqAB0KlkB+AzxN7Ks10116	rigid:OaXQ9NA25fwCWxejPU3Ao9q5j/E	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q5XIE8	uniprotkb:P16036	intact:EBI-15348306|ensembl:ENSRNOP00000023037	intact:EBI-916656	psi-mi:itm2b_rat(display_long)|uniprotkb:Itm2b(gene name)|psi-mi:Itm2b(display_short)|uniprotkb:Immature BRI2(gene name synonym)|uniprotkb:Transmembrane protein BRI(gene name synonym)	psi-mi:mpcp_rat(display_long)|uniprotkb:Phosphate transport protein(gene name synonym)|uniprotkb:Solute carrier family 25 member 3(gene name synonym)|uniprotkb:Slc25a3(gene name)|psi-mi:Slc25a3(display_short)|uniprotkb:Phc(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Martins et al. (2018)	imex:IM-28469|pubmed:29476059	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26438079|imex:IM-28469-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSRNOG00000016271(gene)|ensembl:ENSRNOT00000023037(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001540"(amyloid-beta binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0010008"(endosome membrane)|go:"GO:0030660"(Golgi-associated vesicle membrane)|go:"GO:0031301"(integral component of organelle membrane)|go:"GO:0042985"(negative regulation of amyloid precursor protein biosynthetic process)|interpro:IPR007084(BRICHOS)|interpro:IPR040145|mint:Q5XIE8|refseq:NP_001006964.1|rgd:620727	rgd:70986|interpro:IPR018108|interpro:IPR023395|mint:P16036|interpro:IPR044677|go:"GO:0005315"(inorganic phosphate transmembrane transporter activity)|go:"GO:0005739"(mitochondrion)|go:"GO:0015317"("phosphate:proton symporter activity")|go:"GO:0031305"(integral component of mitochondrial inner membrane)|go:"GO:0035435"(phosphate ion transmembrane transport)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:1990547"(mitochondrial phosphate ion transmembrane transport)	-	-	-	figure legend:ST1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10116(rat-brain-cerebellum)|taxid:10116(Rattus norvegicus)	-	2020/10/30	2020/10/30	rogid:DtE+ZXAZKdCMvUW5K+jXQ5bH07M10116	rogid:BwRf4GKI4G+aBu3r29CqmCdOHyM10116	rigid:OaXQ9NA25fwCWxejPU3Ao9q5j/E	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q5XIE8	uniprotkb:P61980	intact:EBI-15348306|ensembl:ENSRNOP00000023037	intact:EBI-299761|ensembl:ENSRNOP00000025915|uniprotkb:Q07244|uniprotkb:Q15671|uniprotkb:Q60577|uniprotkb:Q922Y7|uniprotkb:Q96J62	psi-mi:itm2b_rat(display_long)|uniprotkb:Itm2b(gene name)|psi-mi:Itm2b(display_short)|uniprotkb:Immature BRI2(gene name synonym)|uniprotkb:Transmembrane protein BRI(gene name synonym)	psi-mi:hnrpk_rat(display_long)|uniprotkb:Hnrnpk(gene name)|psi-mi:Hnrnpk(display_short)|uniprotkb:Hnrpk(gene name synonym)|uniprotkb:dC stretch-binding protein(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Martins et al. (2018)	imex:IM-28469|pubmed:29476059	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26438079|imex:IM-28469-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSRNOG00000016271(gene)|ensembl:ENSRNOT00000023037(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001540"(amyloid-beta binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0010008"(endosome membrane)|go:"GO:0030660"(Golgi-associated vesicle membrane)|go:"GO:0031301"(integral component of organelle membrane)|go:"GO:0042985"(negative regulation of amyloid precursor protein biosynthetic process)|interpro:IPR007084(BRICHOS)|interpro:IPR040145|mint:Q5XIE8|refseq:NP_001006964.1|rgd:620727	ensembl:ENSRNOG00000019113(gene)|ensembl:ENSRNOT00000025916(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000987"(cis-regulatory region sequence-specific DNA binding)|go:"GO:0001541"(ovarian follicle development)|go:"GO:0001822"(kidney development)|go:"GO:0001889"(liver development)|go:"GO:0002102"(podosome)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0003730"(mRNA 3'-UTR binding)|go:"GO:0005521"(lamin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0005938"(cell cortex)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006397"(mRNA processing)|go:"GO:0006953"(acute-phase response)|go:"GO:0007417"(central nervous system development)|go:"GO:0007422"(peripheral nervous system development)|go:"GO:0007568"(aging)|go:"GO:0008380"(RNA splicing)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0010494"(cytoplasmic stress granule)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0010976"(positive regulation of neuron projection development)|go:"GO:0010988"(regulation of low-density lipoprotein particle clearance)|go:"GO:0014069"(postsynaptic density)|go:"GO:0014823"(response to activity)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0021549"(cerebellum development)|go:"GO:0021766"(hippocampus development)|go:"GO:0021987"(cerebral cortex development)|go:"GO:0030324"(lung development)|go:"GO:0030628"(pre-mRNA 3'-splice site binding)|go:"GO:0031072"(heat shock protein binding)|go:"GO:0000785"(chromatin)|go:"GO:0032869"(cellular response to insulin stimulus)|go:"GO:0032993"(protein-DNA complex)|go:"GO:0033120"(positive regulation of RNA splicing)|go:"GO:0042802"(identical protein binding)|go:"GO:0042805"(actinin binding)|go:"GO:0043010"(camera-type eye development)|go:"GO:0043021"(ribonucleoprotein complex binding)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043197"(dendritic spine)|go:"GO:0043679"(axon terminus)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048024"(regulation of mRNA splicing, via spliceosome)|go:"GO:0048025"(negative regulation of mRNA splicing, via spliceosome)|go:"GO:0048260"(positive regulation of receptor-mediated endocytosis)|go:"GO:0048538"(thymus development)|go:"GO:0050804"(modulation of chemical synaptic transmission)|go:"GO:0050806"(positive regulation of synaptic transmission)|go:"GO:0051117"(ATPase binding)|go:"GO:0060999"(positive regulation of dendritic spine development)|go:"GO:0071013"(catalytic step 2 spliceosome)|go:"GO:0071230"(cellular response to amino acid stimulus)|go:"GO:0071333"(cellular response to glucose stimulus)|go:"GO:0032091"(negative regulation of protein binding)|go:"GO:0090129"(positive regulation of synapse maturation)|go:"GO:0098794"(postsynapse)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099175"(regulation of postsynapse organization)|go:"GO:1900273"(positive regulation of long-term synaptic potentiation)|go:"GO:1902074"(response to salt)|go:"GO:1902165"(regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator)|go:"GO:1903861"(positive regulation of dendrite extension)|go:"GO:1904322"(cellular response to forskolin)|go:"GO:1905599"(positive regulation of low-density lipoprotein receptor activity)|go:"GO:1990715"(mRNA CDS binding)|go:"GO:1990829"(C-rich single-stranded DNA binding)|go:"GO:2000010"(positive regulation of protein localization to cell surface)|go:"GO:2000173"(negative regulation of branching morphogenesis of a nerve)|interpro:IPR004087(K Homology)|interpro:IPR004088(K Homology, type 1)|interpro:IPR012987(ROK, N-terminal)|interpro:IPR033090|interpro:IPR036612|mint:P61980|reactome:R-RNO-4570464|reactome:R-RNO-72163|go:"GO:0072752"(cellular response to rapamycin)|rgd:71058|refseq:NP_476482.1|refseq:XP_006253616.1	-	-	-	figure legend:ST1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10116(rat-brain-cerebellum)|taxid:10116(Rattus norvegicus)	-	2020/10/30	2020/10/30	rogid:DtE+ZXAZKdCMvUW5K+jXQ5bH07M10116	rogid:YZQD5JJkHPUMtZ4XUA9fQkNfXzc10116	rigid:OaXQ9NA25fwCWxejPU3Ao9q5j/E	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q5XIE8	uniprotkb:P31000	intact:EBI-15348306|ensembl:ENSRNOP00000023037	intact:EBI-368510	psi-mi:itm2b_rat(display_long)|uniprotkb:Itm2b(gene name)|psi-mi:Itm2b(display_short)|uniprotkb:Immature BRI2(gene name synonym)|uniprotkb:Transmembrane protein BRI(gene name synonym)	psi-mi:vime_rat(display_long)|uniprotkb:Vim(gene name)|psi-mi:Vim(display_short)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Martins et al. (2018)	imex:IM-28469|pubmed:29476059	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26438079|imex:IM-28469-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSRNOG00000016271(gene)|ensembl:ENSRNOT00000023037(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001540"(amyloid-beta binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0010008"(endosome membrane)|go:"GO:0030660"(Golgi-associated vesicle membrane)|go:"GO:0031301"(integral component of organelle membrane)|go:"GO:0042985"(negative regulation of amyloid precursor protein biosynthetic process)|interpro:IPR007084(BRICHOS)|interpro:IPR040145|mint:Q5XIE8|refseq:NP_001006964.1|rgd:620727	go:"GO:0044344"(cellular response to fibroblast growth factor stimulus)|go:"GO:0045098"(type III intermediate filament)|go:"GO:0045103"(intermediate filament-based process)|go:"GO:0045109"(intermediate filament organization)|go:"GO:0045335"(phagocytic vesicle)|go:"GO:0045444"(fat cell differentiation)|go:"GO:0045727"(positive regulation of translation)|go:"GO:0046697"(decidualization)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0050770"(regulation of axonogenesis)|go:"GO:0051721"(protein phosphatase 2A binding)|go:"GO:0060020"(Bergmann glial cell differentiation)|go:"GO:0060252"(positive regulation of glial cell proliferation)|go:"GO:0060395"(SMAD protein signal transduction)|go:"GO:0070307"(lens fiber cell development)|go:"GO:0071222"(cellular response to lipopolysaccharide)|go:"GO:0071225"(cellular response to muramyl dipeptide)|rgd:621646|refseq:NP_112402.1|go:"GO:0097110"(scaffold protein binding)|go:"GO:1900147"(regulation of Schwann cell migration)|go:"GO:1990254"(keratin filament binding)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR006821(Intermediate filament, DNA-binding region)|interpro:IPR018039|interpro:IPR027699|interpro:IPR039008|reactome:R-RNO-264870|reactome:R-RNO-390522|reactome:R-RNO-9013422|reactome:R-RNO-9646399|go:"GO:0071346"(cellular response to interferon-gamma)|go:"GO:0003723"(RNA binding)|go:"GO:0003725"(double-stranded RNA binding)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005200"(structural constituent of cytoskeleton)|go:"GO:0005212"(structural constituent of eye lens)|go:"GO:0005737"(cytoplasm)|go:"GO:0005777"(peroxisome)|go:"GO:0005829"(cytosol)|go:"GO:0005844"(polysome)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005882"(intermediate filament)|go:"GO:0005886"(plasma membrane)|go:"GO:0007568"(aging)|go:"GO:0009314"(response to radiation)|go:"GO:0010269"(response to selenium ion)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010977"(negative regulation of neuron projection development)|go:"GO:0014002"(astrocyte development)|go:"GO:0016363"(nuclear matrix)|go:"GO:0019900"(kinase binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030424"(axon)|go:"GO:0031252"(cell leading edge)|go:"GO:0032355"(response to estradiol)|go:"GO:0032967"(positive regulation of collagen biosynthetic process)|go:"GO:0033280"(response to vitamin D)|go:"GO:0042802"(identical protein binding)|go:"GO:0042995"(cell projection)|go:"GO:0043005"(neuron projection)|go:"GO:0043403"(skeletal muscle tissue regeneration)|go:"GO:0043488"(regulation of mRNA stability)|go:"GO:0044297"(cell body)|go:"GO:0010043"(response to zinc ion)|mint:P31000|dip:DIP-31882N	-	-	-	figure legend:ST1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10116(rat-brain-cerebellum)|taxid:10116(Rattus norvegicus)	-	2020/10/30	2020/10/30	rogid:DtE+ZXAZKdCMvUW5K+jXQ5bH07M10116	rogid:gXqxWYjgPhNbQNfJNwdt/Q4D4u010116	rigid:OaXQ9NA25fwCWxejPU3Ao9q5j/E	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q5XIE8	uniprotkb:P70566	intact:EBI-15348306|ensembl:ENSRNOP00000023037	intact:EBI-16221588|ensembl:ENSRNOP00000014124	psi-mi:itm2b_rat(display_long)|uniprotkb:Itm2b(gene name)|psi-mi:Itm2b(display_short)|uniprotkb:Immature BRI2(gene name synonym)|uniprotkb:Transmembrane protein BRI(gene name synonym)	psi-mi:tmod2_rat(display_long)|uniprotkb:Tmod2(gene name)|psi-mi:Tmod2(display_short)|uniprotkb:Ntmod(gene name synonym)|uniprotkb:Neuronal tropomodulin(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Martins et al. (2018)	imex:IM-28469|pubmed:29476059	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26438079|imex:IM-28469-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSRNOG00000016271(gene)|ensembl:ENSRNOT00000023037(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001540"(amyloid-beta binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0010008"(endosome membrane)|go:"GO:0030660"(Golgi-associated vesicle membrane)|go:"GO:0031301"(integral component of organelle membrane)|go:"GO:0042985"(negative regulation of amyloid precursor protein biosynthetic process)|interpro:IPR007084(BRICHOS)|interpro:IPR040145|mint:Q5XIE8|refseq:NP_001006964.1|rgd:620727	ensembl:ENSRNOG00000010447(gene)|ensembl:ENSRNOT00000014124(transcript)|go:"GO:0003779"(actin binding)|go:"GO:0005523"(tropomyosin binding)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005865"(striated muscle thin filament)|go:"GO:0006936"(muscle contraction)|go:"GO:0007015"(actin filament organization)|go:"GO:0007270"(neuron-neuron synaptic transmission)|go:"GO:0007611"(learning or memory)|go:"GO:0030016"(myofibril)|go:"GO:0030239"(myofibril assembly)|go:"GO:0030426"(growth cone)|go:"GO:0043005"(neuron projection)|go:"GO:0045202"(synapse)|go:"GO:0045745"(positive regulation of G protein-coupled receptor signaling pathway)|go:"GO:0051694"(pointed-end actin filament capping)|interpro:IPR004934(Tropomodulin)|interpro:IPR030130|interpro:IPR032675|mint:P70566|reactome:R-RNO-390522|rgd:61948|refseq:NP_113801.1|refseq:XP_006243469.1|refseq:XP_006243470.1|refseq:XP_008764553.1|refseq:XP_017451363.1	-	-	-	figure legend:ST1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10116(rat-brain-cerebellum)|taxid:10116(Rattus norvegicus)	-	2020/10/30	2020/10/30	rogid:DtE+ZXAZKdCMvUW5K+jXQ5bH07M10116	rogid:NZcqpDi6faan3J/6MGaDvpwkfX810116	rigid:OaXQ9NA25fwCWxejPU3Ao9q5j/E	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q5XIE8	uniprotkb:P97610	intact:EBI-15348306|ensembl:ENSRNOP00000023037	intact:EBI-26437627|ensembl:ENSRNOP00000026153	psi-mi:itm2b_rat(display_long)|uniprotkb:Itm2b(gene name)|psi-mi:Itm2b(display_short)|uniprotkb:Immature BRI2(gene name synonym)|uniprotkb:Transmembrane protein BRI(gene name synonym)	psi-mi:syt12_rat(display_long)|uniprotkb:Syt12(gene name)|psi-mi:Syt12(display_short)|uniprotkb:Srg1(gene name synonym)|uniprotkb:Sytr1(gene name synonym)|uniprotkb:Synaptotagmin XII(gene name synonym)|uniprotkb:Synaptotagmin-related gene 1 protein(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Martins et al. (2018)	imex:IM-28469|pubmed:29476059	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26438079|imex:IM-28469-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSRNOG00000016271(gene)|ensembl:ENSRNOT00000023037(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001540"(amyloid-beta binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0010008"(endosome membrane)|go:"GO:0030660"(Golgi-associated vesicle membrane)|go:"GO:0031301"(integral component of organelle membrane)|go:"GO:0042985"(negative regulation of amyloid precursor protein biosynthetic process)|interpro:IPR007084(BRICHOS)|interpro:IPR040145|mint:Q5XIE8|refseq:NP_001006964.1|rgd:620727	ensembl:ENSRNOG00000019306(gene)|ensembl:ENSRNOT00000026152(transcript)|go:"GO:0000149"(SNARE binding)|go:"GO:0001786"(phosphatidylserine binding)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005544"(calcium-dependent phospholipid binding)|go:"GO:0005886"(plasma membrane)|go:"GO:0014059"(regulation of dopamine secretion)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016192"(vesicle-mediated transport)|go:"GO:0017156"(calcium-ion regulated exocytosis)|go:"GO:0017158"(regulation of calcium ion-dependent exocytosis)|go:"GO:0019905"(syntaxin binding)|go:"GO:0030276"(clathrin binding)|go:"GO:0030672"(synaptic vesicle membrane)|go:"GO:0046928"(regulation of neurotransmitter secretion)|go:"GO:0048792"(spontaneous exocytosis of neurotransmitter)|go:"GO:0060291"(long-term synaptic potentiation)|go:"GO:0070382"(exocytic vesicle)|go:"GO:0071277"(cellular response to calcium ion)|go:"GO:0098686"(hippocampal mossy fiber to CA3 synapse)|go:"GO:0098793"(presynapse)|interpro:IPR000008(C2 calcium-dependent membrane targeting)|interpro:IPR030537|interpro:IPR035892|mint:P97610|refseq:NP_620190.1|rgd:621876	-	-	-	figure legend:ST1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10116(rat-brain-cerebellum)|taxid:10116(Rattus norvegicus)	-	2020/10/30	2020/10/30	rogid:DtE+ZXAZKdCMvUW5K+jXQ5bH07M10116	rogid:J1OnAWaV8g9oWmhRGOxK8VddyJs10116	rigid:OaXQ9NA25fwCWxejPU3Ao9q5j/E	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q5XIE8	uniprotkb:Q62876	intact:EBI-15348306|ensembl:ENSRNOP00000023037	intact:EBI-15349536|ensembl:ENSRNOP00000023066	psi-mi:itm2b_rat(display_long)|uniprotkb:Itm2b(gene name)|psi-mi:Itm2b(display_short)|uniprotkb:Immature BRI2(gene name synonym)|uniprotkb:Transmembrane protein BRI(gene name synonym)	psi-mi:sng1_rat(display_long)|uniprotkb:Syngr1(gene name)|psi-mi:Syngr1(display_short)|uniprotkb:p29(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Martins et al. (2018)	imex:IM-28469|pubmed:29476059	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26438079|imex:IM-28469-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSRNOG00000016271(gene)|ensembl:ENSRNOT00000023037(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001540"(amyloid-beta binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0010008"(endosome membrane)|go:"GO:0030660"(Golgi-associated vesicle membrane)|go:"GO:0031301"(integral component of organelle membrane)|go:"GO:0042985"(negative regulation of amyloid precursor protein biosynthetic process)|interpro:IPR007084(BRICHOS)|interpro:IPR040145|mint:Q5XIE8|refseq:NP_001006964.1|rgd:620727	ensembl:ENSRNOT00000023066(transcript)|go:"GO:0006605"(protein targeting)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0030285"(integral component of synaptic vesicle membrane)|go:"GO:0030672"(synaptic vesicle membrane)|go:"GO:0031594"(neuromuscular junction)|go:"GO:0042470"(melanosome)|go:"GO:0043195"(terminal bouton)|go:"GO:0045055"(regulated exocytosis)|go:"GO:0048169"(regulation of long-term neuronal synaptic plasticity)|ensembl:ENSRNOG00000017108(gene)|go:"GO:0048172"(regulation of short-term neuronal synaptic plasticity)|go:"GO:0048499"(synaptic vesicle membrane organization)|go:"GO:1990830"(cellular response to leukemia inhibitory factor)|interpro:IPR008253(Marvel)|interpro:IPR016579(Synaptogyrin)|mint:Q62876|reactome:R-RNO-6798695|rgd:3801|refseq:NP_062039.1	-	-	-	figure legend:ST1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10116(rat-brain-cerebellum)|taxid:10116(Rattus norvegicus)	-	2020/10/30	2020/10/30	rogid:DtE+ZXAZKdCMvUW5K+jXQ5bH07M10116	rogid:BLWDXZqURmVydl4j/e8DPDiiuK010116	rigid:OaXQ9NA25fwCWxejPU3Ao9q5j/E	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q5XIE8	uniprotkb:Q9QWN8	intact:EBI-15348306|ensembl:ENSRNOP00000023037	intact:EBI-26373337|uniprotkb:O88197|uniprotkb:Q9ES68	psi-mi:itm2b_rat(display_long)|uniprotkb:Itm2b(gene name)|psi-mi:Itm2b(display_short)|uniprotkb:Immature BRI2(gene name synonym)|uniprotkb:Transmembrane protein BRI(gene name synonym)	psi-mi:sptn2_rat(display_long)|uniprotkb:Beta SpIII sigma 1(gene name synonym)|uniprotkb:Beta-III spectrin(gene name synonym)|uniprotkb:Glutamate transporter EAAT4-associated protein 41(gene name synonym)|uniprotkb:SPNB-3(gene name synonym)|uniprotkb:Spectrin-like protein GTRAP41(gene name synonym)|uniprotkb:Sptbn2(gene name)|psi-mi:Sptbn2(display_short)|uniprotkb:Spnb3(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Martins et al. (2018)	imex:IM-28469|pubmed:29476059	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26438079|imex:IM-28469-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSRNOG00000016271(gene)|ensembl:ENSRNOT00000023037(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001540"(amyloid-beta binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0010008"(endosome membrane)|go:"GO:0030660"(Golgi-associated vesicle membrane)|go:"GO:0031301"(integral component of organelle membrane)|go:"GO:0042985"(negative regulation of amyloid precursor protein biosynthetic process)|interpro:IPR007084(BRICHOS)|interpro:IPR040145|mint:Q5XIE8|refseq:NP_001006964.1|rgd:620727	go:"GO:0000139"(Golgi membrane)|go:"GO:0003779"(actin binding)|go:"GO:0005200"(structural constituent of cytoskeleton)|go:"GO:0005543"(phospholipid binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0007416"(synapse assembly)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0008091"(spectrin)|go:"GO:0016079"(synaptic vesicle exocytosis)|go:"GO:0016081"(synaptic vesicle docking)|go:"GO:0016192"(vesicle-mediated transport)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0016363"(nuclear matrix)|go:"GO:0017158"(regulation of calcium ion-dependent exocytosis)|go:"GO:0021692"(cerebellar Purkinje cell layer morphogenesis)|go:"GO:0030534"(adult behavior)|go:"GO:0035264"(multicellular organism growth)|go:"GO:0043025"(neuronal cell body)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051693"(actin filament capping)|go:"GO:0071361"(cellular response to ethanol)|go:"GO:0098688"(parallel fiber to Purkinje cell synapse)|go:"GO:0098793"(presynapse)|go:"GO:0098918"(structural constituent of synapse)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099173"(postsynapse organization)|go:"GO:0099189"(postsynaptic spectrin-associated cytoskeleton)|reactome:R-RNO-2132295|reactome:R-RNO-375165|reactome:R-RNO-445095|reactome:R-RNO-5673001|reactome:R-RNO-6807878|rgd:3751|mint:Q9QWN8|interpro:IPR001589(Actinin-type, actin-binding, conserved site)|interpro:IPR001715(Calponin-like actin-binding)|interpro:IPR036872|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR041681|interpro:IPR001605(Spectrin/pleckstrin-like)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR018159|interpro:IPR016343(Spectrin, beta subunit)|interpro:IPR002017(Spectrin repeat)	-	-	-	figure legend:ST1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10116(rat-brain-cerebellum)|taxid:10116(Rattus norvegicus)	-	2020/10/30	2020/10/30	rogid:DtE+ZXAZKdCMvUW5K+jXQ5bH07M10116	rogid:mYeNz7x0BsYG5aS/meqBSkzcX0M10116	rigid:OaXQ9NA25fwCWxejPU3Ao9q5j/E	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q5XIE8	uniprotkb:Q9JHY2	intact:EBI-15348306|ensembl:ENSRNOP00000023037	intact:EBI-919945	psi-mi:itm2b_rat(display_long)|uniprotkb:Itm2b(gene name)|psi-mi:Itm2b(display_short)|uniprotkb:Immature BRI2(gene name synonym)|uniprotkb:Transmembrane protein BRI(gene name synonym)	psi-mi:sfxn3_rat(display_long)|uniprotkb:Sfxn3(gene name)|psi-mi:Sfxn3(display_short)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Martins et al. (2018)	imex:IM-28469|pubmed:29476059	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26438079|imex:IM-28469-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSRNOG00000016271(gene)|ensembl:ENSRNOT00000023037(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001540"(amyloid-beta binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0010008"(endosome membrane)|go:"GO:0030660"(Golgi-associated vesicle membrane)|go:"GO:0031301"(integral component of organelle membrane)|go:"GO:0042985"(negative regulation of amyloid precursor protein biosynthetic process)|interpro:IPR007084(BRICHOS)|interpro:IPR040145|mint:Q5XIE8|refseq:NP_001006964.1|rgd:620727	rgd:620716|refseq:NP_075237.1|interpro:IPR004686(Tricarboxylate/iron carrier)|mint:Q9JHY2|go:"GO:0005371"(tricarboxylate secondary active transmembrane transporter activity)|go:"GO:0005739"(mitochondrion)|go:"GO:0006730"(one-carbon metabolic process)|go:"GO:0022857"(transmembrane transporter activity)|go:"GO:0022889"(serine transmembrane transporter activity)|go:"GO:0031305"(integral component of mitochondrial inner membrane)|go:"GO:0031966"(mitochondrial membrane)|go:"GO:0140300"(serine import into mitochondrion)|go:"GO:1990542"(mitochondrial transmembrane transport)	-	-	-	figure legend:ST1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10116(rat-brain-cerebellum)|taxid:10116(Rattus norvegicus)	-	2020/10/30	2020/10/30	rogid:DtE+ZXAZKdCMvUW5K+jXQ5bH07M10116	rogid:KXWPONNXXrT71ucMJjKuHe6V+EE10116	rigid:OaXQ9NA25fwCWxejPU3Ao9q5j/E	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q5XIE8	uniprotkb:B3GNI6	intact:EBI-15348306|ensembl:ENSRNOP00000023037	intact:EBI-2009404|uniprotkb:B3DMA8|uniprotkb:B3GNI4	psi-mi:itm2b_rat(display_long)|uniprotkb:Itm2b(gene name)|psi-mi:Itm2b(display_short)|uniprotkb:Immature BRI2(gene name synonym)|uniprotkb:Transmembrane protein BRI(gene name synonym)	psi-mi:sep11_rat(display_long)|uniprotkb:Septin11(gene name)|psi-mi:Septin11(display_short)|uniprotkb:Sept11(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Martins et al. (2018)	imex:IM-28469|pubmed:29476059	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26438079|imex:IM-28469-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSRNOG00000016271(gene)|ensembl:ENSRNOT00000023037(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001540"(amyloid-beta binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0010008"(endosome membrane)|go:"GO:0030660"(Golgi-associated vesicle membrane)|go:"GO:0031301"(integral component of organelle membrane)|go:"GO:0042985"(negative regulation of amyloid precursor protein biosynthetic process)|interpro:IPR007084(BRICHOS)|interpro:IPR040145|mint:Q5XIE8|refseq:NP_001006964.1|rgd:620727	interpro:IPR030379|rgd:1307405|refseq:NP_001100678.1|interpro:IPR016491(Septin)|mint:B3GNI6|interpro:IPR027417|go:"GO:0001725"(stress fiber)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005940"(septin ring)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0030424"(axon)|go:"GO:0031105"(septin complex)|go:"GO:0032153"(cell division site)|go:"GO:0034613"(cellular protein localization)|go:"GO:0043197"(dendritic spine)|go:"GO:0050807"(regulation of synapse organization)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0061640"(cytoskeleton-dependent cytokinesis)|go:"GO:0098794"(postsynapse)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0098982"(GABA-ergic synapse)|go:"GO:0099629"(postsynaptic specialization of symmetric synapse)	-	-	-	figure legend:ST1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10116(rat-brain-cerebellum)|taxid:10116(Rattus norvegicus)	-	2020/10/30	2020/10/30	rogid:DtE+ZXAZKdCMvUW5K+jXQ5bH07M10116	rogid:RfdukqyhC/1qeJHPQmrz7ryDmdY10116	rigid:OaXQ9NA25fwCWxejPU3Ao9q5j/E	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q5XIE8	uniprotkb:D4AE41	intact:EBI-15348306|ensembl:ENSRNOP00000023037	intact:EBI-22237303	psi-mi:itm2b_rat(display_long)|uniprotkb:Itm2b(gene name)|psi-mi:Itm2b(display_short)|uniprotkb:Immature BRI2(gene name synonym)|uniprotkb:Transmembrane protein BRI(gene name synonym)	psi-mi:rmxl1_rat(display_long)|uniprotkb:Heterogeneous nuclear ribonucleoprotein G-like 1(gene name synonym)|uniprotkb:Rbmxl1(gene name)|psi-mi:Rbmxl1(display_short)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Martins et al. (2018)	imex:IM-28469|pubmed:29476059	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26438079|imex:IM-28469-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSRNOG00000016271(gene)|ensembl:ENSRNOT00000023037(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001540"(amyloid-beta binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0010008"(endosome membrane)|go:"GO:0030660"(Golgi-associated vesicle membrane)|go:"GO:0031301"(integral component of organelle membrane)|go:"GO:0042985"(negative regulation of amyloid precursor protein biosynthetic process)|interpro:IPR007084(BRICHOS)|interpro:IPR040145|mint:Q5XIE8|refseq:NP_001006964.1|rgd:620727	go:"GO:0003723"(RNA binding)|go:"GO:0005681"(spliceosomal complex)|go:"GO:0006397"(mRNA processing)|go:"GO:0008380"(RNA splicing)|go:"GO:0048026"(positive regulation of mRNA splicing, via spliceosome)|mint:D4AE41|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR035979|interpro:IPR012604(RBM1CTR)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR003954(RNA recognition, region 1)|rgd:1585845	-	-	-	figure legend:ST1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10116(rat-brain-cerebellum)|taxid:10116(Rattus norvegicus)	-	2020/10/30	2020/10/30	rogid:DtE+ZXAZKdCMvUW5K+jXQ5bH07M10116	rogid:ozGuiB8V5solV2Fy6BBUnRL0S6U10116	rigid:OaXQ9NA25fwCWxejPU3Ao9q5j/E	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q5XIE8	uniprotkb:Q6NYB7	intact:EBI-15348306|ensembl:ENSRNOP00000023037	intact:EBI-918913|uniprotkb:P05711|ensembl:ENSRNOP00000073493	psi-mi:itm2b_rat(display_long)|uniprotkb:Itm2b(gene name)|psi-mi:Itm2b(display_short)|uniprotkb:Immature BRI2(gene name synonym)|uniprotkb:Transmembrane protein BRI(gene name synonym)	psi-mi:rab1a_rat(display_long)|uniprotkb:Rab1A(gene name)|psi-mi:Rab1A(display_short)|uniprotkb:Rab1(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Martins et al. (2018)	imex:IM-28469|pubmed:29476059	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26438079|imex:IM-28469-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSRNOG00000016271(gene)|ensembl:ENSRNOT00000023037(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001540"(amyloid-beta binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0010008"(endosome membrane)|go:"GO:0030660"(Golgi-associated vesicle membrane)|go:"GO:0031301"(integral component of organelle membrane)|go:"GO:0042985"(negative regulation of amyloid precursor protein biosynthetic process)|interpro:IPR007084(BRICHOS)|interpro:IPR040145|mint:Q5XIE8|refseq:NP_001006964.1|rgd:620727	rgd:619736|refseq:NP_112352.2|ensembl:ENSRNOG00000004992(gene)|ensembl:ENSRNOT00000084481(transcript)|go:"GO:0000045"(autophagosome assembly)|go:"GO:0000139"(Golgi membrane)|go:"GO:0003924"(GTPase activity)|go:"GO:0003925"(G protein activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005769"(early endosome)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0006897"(endocytosis)|go:"GO:0006914"(autophagy)|go:"GO:0007030"(Golgi organization)|go:"GO:0012505"(endomembrane system)|go:"GO:0016477"(cell migration)|go:"GO:0019068"(virion assembly)|go:"GO:0030252"(growth hormone secretion)|go:"GO:0032402"(melanosome transport)|go:"GO:0032482"(Rab protein signal transduction)|go:"GO:0032757"(positive regulation of interleukin-8 production)|go:"GO:0034446"(substrate adhesion-dependent cell spreading)|go:"GO:0042470"(melanosome)|go:"GO:0042742"(defense response to bacterium)|go:"GO:0043025"(neuronal cell body)|go:"GO:0047496"(vesicle transport along microtubule)|go:"GO:0090110"(COPII-coated vesicle cargo loading)|go:"GO:0098793"(presynapse)|go:"GO:1903020"(positive regulation of glycoprotein metabolic process)|interpro:IPR001806(Ras GTPase)|interpro:IPR005225(Small GTP-binding protein)|interpro:IPR027417|mint:Q6NYB7|reactome:R-RNO-162658|reactome:R-RNO-204005|reactome:R-RNO-6807878|reactome:R-RNO-6811434|reactome:R-RNO-8873719|reactome:R-RNO-8876198	-	-	-	figure legend:ST1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10116(rat-brain-cerebellum)|taxid:10116(Rattus norvegicus)	-	2020/10/30	2020/10/30	rogid:DtE+ZXAZKdCMvUW5K+jXQ5bH07M10116	rogid:Pa9NYKiCNXtxRwthh1r/pGbZyf010116	rigid:OaXQ9NA25fwCWxejPU3Ao9q5j/E	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q5XIE8	uniprotkb:P61107	intact:EBI-15348306|ensembl:ENSRNOP00000023037	intact:EBI-917845|uniprotkb:P35287|uniprotkb:Q969L0|uniprotkb:Q9UI11	psi-mi:itm2b_rat(display_long)|uniprotkb:Itm2b(gene name)|psi-mi:Itm2b(display_short)|uniprotkb:Immature BRI2(gene name synonym)|uniprotkb:Transmembrane protein BRI(gene name synonym)	psi-mi:rab14_rat(display_long)|uniprotkb:Rab14(gene name)|psi-mi:Rab14(display_short)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Martins et al. (2018)	imex:IM-28469|pubmed:29476059	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26438079|imex:IM-28469-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSRNOG00000016271(gene)|ensembl:ENSRNOT00000023037(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001540"(amyloid-beta binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0010008"(endosome membrane)|go:"GO:0030660"(Golgi-associated vesicle membrane)|go:"GO:0031301"(integral component of organelle membrane)|go:"GO:0042985"(negative regulation of amyloid precursor protein biosynthetic process)|interpro:IPR007084(BRICHOS)|interpro:IPR040145|mint:Q5XIE8|refseq:NP_001006964.1|rgd:620727	rgd:620881|refseq:NP_446041.1|interpro:IPR005225(Small GTP-binding protein)|interpro:IPR001806(Ras GTPase)|interpro:IPR030702|interpro:IPR027417|mint:P61107|go:"GO:0000139"(Golgi membrane)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005764"(lysosome)|go:"GO:0005769"(early endosome)|go:"GO:0005770"(late endosome)|go:"GO:0005791"(rough endoplasmic reticulum)|go:"GO:0005795"(Golgi stack)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006895"(Golgi to endosome transport)|go:"GO:0007589"(body fluid secretion)|go:"GO:0008543"(fibroblast growth factor receptor signaling pathway)|go:"GO:0012505"(endomembrane system)|go:"GO:0016192"(vesicle-mediated transport)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0019003"(GDP binding)|go:"GO:0030133"(transport vesicle)|go:"GO:0030140"(trans-Golgi network transport vesicle)|go:"GO:0030659"(cytoplasmic vesicle membrane)|go:"GO:0031489"(myosin V binding)|go:"GO:0031901"(early endosome membrane)|go:"GO:0032456"(endocytic recycling)|go:"GO:0032880"(regulation of protein localization)|go:"GO:0042175"(nuclear outer membrane-endoplasmic reticulum membrane network)|go:"GO:0042742"(defense response to bacterium)|go:"GO:0045176"(apical protein localization)|go:"GO:0045335"(phagocytic vesicle)|go:"GO:0045995"(regulation of embryonic development)|go:"GO:0046907"(intracellular transport)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0055037"(recycling endosome)|go:"GO:0090387"(phagolysosome assembly involved in apoptotic cell clearance)|go:"GO:0097208"(alveolar lamellar body)|go:"GO:0098993"(anchored component of synaptic vesicle membrane)|reactome:R-RNO-1660499|reactome:R-RNO-6798695|reactome:R-RNO-8873719|reactome:R-RNO-8876198	-	-	-	figure legend:ST1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10116(rat-brain-cerebellum)|taxid:10116(Rattus norvegicus)	-	2020/10/30	2020/10/30	rogid:DtE+ZXAZKdCMvUW5K+jXQ5bH07M10116	rogid:KPCWiyc6plQCbqAnsREsHrR61LM10116	rigid:OaXQ9NA25fwCWxejPU3Ao9q5j/E	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q5XIE8	uniprotkb:Q6RUV5	intact:EBI-15348306|ensembl:ENSRNOP00000023037	intact:EBI-919251|ensembl:ENSRNOP00000001417	psi-mi:itm2b_rat(display_long)|uniprotkb:Itm2b(gene name)|psi-mi:Itm2b(display_short)|uniprotkb:Immature BRI2(gene name synonym)|uniprotkb:Transmembrane protein BRI(gene name synonym)	psi-mi:rac1_rat(display_long)|uniprotkb:Rac1(gene name)|psi-mi:Rac1(display_short)|uniprotkb:p21-Rac1(gene name synonym)|uniprotkb:Rac(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Martins et al. (2018)	imex:IM-28469|pubmed:29476059	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26438079|imex:IM-28469-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSRNOG00000016271(gene)|ensembl:ENSRNOT00000023037(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001540"(amyloid-beta binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0010008"(endosome membrane)|go:"GO:0030660"(Golgi-associated vesicle membrane)|go:"GO:0031301"(integral component of organelle membrane)|go:"GO:0042985"(negative regulation of amyloid precursor protein biosynthetic process)|interpro:IPR007084(BRICHOS)|interpro:IPR040145|mint:Q5XIE8|refseq:NP_001006964.1|rgd:620727	rgd:619755|refseq:NP_599193.1|dip:DIP-37114N|ensembl:ENSRNOG00000001068(gene)|ensembl:ENSRNOT00000001417(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0000242"(pericentriolar material)|go:"GO:0001764"(neuron migration)|go:"GO:0001891"(phagocytic cup)|go:"GO:0001934"(positive regulation of protein phosphorylation)|go:"GO:0002093"(auditory receptor cell morphogenesis)|go:"GO:0002551"(mast cell chemotaxis)|go:"GO:0003376"(sphingosine-1-phosphate receptor signaling pathway)|go:"GO:0003382"(epithelial cell morphogenesis)|go:"GO:0003924"(GTPase activity)|go:"GO:0003925"(G protein activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005884"(actin filament)|go:"GO:0005886"(plasma membrane)|go:"GO:0005938"(cell cortex)|go:"GO:0006897"(endocytosis)|go:"GO:0006911"(phagocytosis, engulfment)|go:"GO:0006935"(chemotaxis)|go:"GO:0006972"(hyperosmotic response)|go:"GO:0007010"(cytoskeleton organization)|go:"GO:0007015"(actin filament organization)|go:"GO:0007155"(cell adhesion)|go:"GO:0007163"(establishment or maintenance of cell polarity)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0007264"(small GTPase mediated signal transduction)|go:"GO:0007411"(axon guidance)|go:"GO:0008045"(motor neuron axon guidance)|go:"GO:0008283"(cell population proliferation)|go:"GO:0008360"(regulation of cell shape)|go:"GO:0008361"(regulation of cell size)|go:"GO:0010591"(regulation of lamellipodium assembly)|go:"GO:0010592"(positive regulation of lamellipodium assembly)|go:"GO:0010595"(positive regulation of endothelial cell migration)|go:"GO:0010762"(regulation of fibroblast migration)|go:"GO:0010764"(negative regulation of fibroblast migration)|go:"GO:0010811"(positive regulation of cell-substrate adhesion)|go:"GO:0014041"(regulation of neuron maturation)|go:"GO:0016020"(membrane)|go:"GO:0016358"(dendrite development)|go:"GO:0016477"(cell migration)|go:"GO:0016601"(Rac protein signal transduction)|go:"GO:0019897"(extrinsic component of plasma membrane)|go:"GO:0019899"(enzyme binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0021799"(cerebral cortex radially oriented cell migration)|go:"GO:0021831"(embryonic olfactory bulb interneuron precursor migration)|go:"GO:0021894"(cerebral cortex GABAergic interneuron development)|go:"GO:0022604"(regulation of cell morphogenesis)|go:"GO:0030027"(lamellipodium)|go:"GO:0030031"(cell projection assembly)|go:"GO:0030032"(lamellipodium assembly)|go:"GO:0030036"(actin cytoskeleton organization)|go:"GO:0030041"(actin filament polymerization)|go:"GO:0030334"(regulation of cell migration)|go:"GO:0030742"(GTP-dependent protein binding)|go:"GO:0030838"(positive regulation of actin filament polymerization)|go:"GO:0030865"(cortical cytoskeleton organization)|go:"GO:0030900"(forebrain development)|go:"GO:0031116"(positive regulation of microtubule polymerization)|go:"GO:0031234"(extrinsic component of cytoplasmic side of plasma membrane)|go:"GO:0031267"(small GTPase binding)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0031529"(ruffle organization)|go:"GO:0031901"(early endosome membrane)|go:"GO:0031996"(thioesterase binding)|go:"GO:0032587"(ruffle membrane)|go:"GO:0032707"(negative regulation of interleukin-23 production)|go:"GO:0032956"(regulation of actin cytoskeleton organization)|go:"GO:0034446"(substrate adhesion-dependent cell spreading)|go:"GO:0035567"(non-canonical Wnt signaling pathway)|go:"GO:0035774"(positive regulation of insulin secretion involved in cellular response to glucose stimulus)|go:"GO:0036464"(cytoplasmic ribonucleoprotein granule)|go:"GO:0042470"(melanosome)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0042995"(cell projection)|go:"GO:0043197"(dendritic spine)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0043552"(positive regulation of phosphatidylinositol 3-kinase activity)|go:"GO:0043652"(engulfment of apoptotic cell)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045216"(cell-cell junction organization)|go:"GO:0045428"(regulation of nitric oxide biosynthetic process)|go:"GO:0045453"(bone resorption)|go:"GO:0045740"(positive regulation of DNA replication)|go:"GO:0046425"(regulation of receptor signaling pathway via JAK-STAT)|go:"GO:0048012"(hepatocyte growth factor receptor signaling pathway)|go:"GO:0048168"(regulation of neuronal synaptic plasticity)|go:"GO:0048532"(anatomical structure arrangement)|go:"GO:0048812"(neuron projection morphogenesis)|go:"GO:0048813"(dendrite morphogenesis)|go:"GO:0048870"(cell motility)|go:"GO:0048873"(homeostasis of number of cells within a tissue)|go:"GO:0051022"(Rho GDP-dissociation inhibitor binding)|go:"GO:0051117"(ATPase binding)|go:"GO:0051492"(regulation of stress fiber assembly)|go:"GO:0051496"(positive regulation of stress fiber assembly)|go:"GO:0051668"(localization within membrane)|go:"GO:0051894"(positive regulation of focal adhesion assembly)|go:"GO:0051932"(synaptic transmission, GABAergic)|go:"GO:0055038"(recycling endosome membrane)|go:"GO:0060071"(Wnt signaling pathway, planar cell polarity pathway)|go:"GO:0060091"(kinocilium)|go:"GO:0060263"(regulation of respiratory burst)|go:"GO:0060999"(positive regulation of dendritic spine development)|go:"GO:0061344"(regulation of cell adhesion involved in heart morphogenesis)|go:"GO:0071260"(cellular response to mechanical stimulus)|go:"GO:0071526"(semaphorin-plexin signaling pathway)|go:"GO:0071542"(dopaminergic neuron differentiation)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0090023"(positive regulation of neutrophil chemotaxis)|go:"GO:0090103"(cochlea morphogenesis)|go:"GO:0097178"(ruffle assembly)|go:"GO:0098794"(postsynapse)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:1900026"(positive regulation of substrate adhesion-dependent cell spreading)|go:"GO:1902622"(regulation of neutrophil migration)|go:"GO:1904948"(midbrain dopaminergic neuron differentiation)|go:"GO:2000386"(positive regulation of ovarian follicle development)|interpro:IPR001806(Ras GTPase)|interpro:IPR003578(Ras small GTPase, Rho type)|interpro:IPR005225(Small GTP-binding protein)|interpro:IPR027417|mint:Q6RUV5|reactome:R-RNO-114604|reactome:R-RNO-1257604|reactome:R-RNO-1433557|reactome:R-RNO-193648|reactome:R-RNO-2029482|reactome:R-RNO-2424491|reactome:R-RNO-2871796|reactome:R-RNO-376172|reactome:R-RNO-389359|reactome:R-RNO-3928662|reactome:R-RNO-3928664|reactome:R-RNO-3928665|reactome:R-RNO-399954|reactome:R-RNO-4086400|reactome:R-RNO-416550|reactome:R-RNO-418885|reactome:R-RNO-4420097|reactome:R-RNO-445144|reactome:R-RNO-5218920|reactome:R-RNO-5625740|reactome:R-RNO-5625900|reactome:R-RNO-5625970|reactome:R-RNO-5626467|reactome:R-RNO-5627123|reactome:R-RNO-5663213|reactome:R-RNO-5663220|reactome:R-RNO-5668599|reactome:R-RNO-5687128|reactome:R-RNO-6798695|reactome:R-RNO-6811558|reactome:R-RNO-8849471|reactome:R-RNO-8875555|reactome:R-RNO-9013149|reactome:R-RNO-9032759|reactome:R-RNO-983231	-	-	-	figure legend:ST1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10116(rat-brain-cerebellum)|taxid:10116(Rattus norvegicus)	-	2020/10/30	2020/10/30	rogid:DtE+ZXAZKdCMvUW5K+jXQ5bH07M10116	rogid:8rkYyZSFL5tIfbRNKZgP/UDxD+A10116	rigid:OaXQ9NA25fwCWxejPU3Ao9q5j/E	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q5XIE8	uniprotkb:O88778	intact:EBI-15348306|ensembl:ENSRNOP00000023037	intact:EBI-2271660	psi-mi:itm2b_rat(display_long)|uniprotkb:Itm2b(gene name)|psi-mi:Itm2b(display_short)|uniprotkb:Immature BRI2(gene name synonym)|uniprotkb:Transmembrane protein BRI(gene name synonym)	psi-mi:bsn_rat(display_long)|uniprotkb:Bsn(gene name)|psi-mi:Bsn(display_short)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Martins et al. (2018)	imex:IM-28469|pubmed:29476059	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26438079|imex:IM-28469-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSRNOG00000016271(gene)|ensembl:ENSRNOT00000023037(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001540"(amyloid-beta binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0010008"(endosome membrane)|go:"GO:0030660"(Golgi-associated vesicle membrane)|go:"GO:0031301"(integral component of organelle membrane)|go:"GO:0042985"(negative regulation of amyloid precursor protein biosynthetic process)|interpro:IPR007084(BRICHOS)|interpro:IPR040145|mint:Q5XIE8|refseq:NP_001006964.1|rgd:620727	rgd:2223|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|interpro:IPR008899(Zinc finger, piccolo-type)|interpro:IPR030627|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|mint:O88778|go:"GO:0001222"(transcription corepressor binding)|go:"GO:0005798"(Golgi-associated vesicle)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0007010"(cytoskeleton organization)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0008088"(axo-dendritic transport)|go:"GO:0008090"(retrograde axonal transport)|go:"GO:0009986"(cell surface)|go:"GO:0014069"(postsynaptic density)|go:"GO:0019898"(extrinsic component of membrane)|go:"GO:0030424"(axon)|go:"GO:0030425"(dendrite)|go:"GO:0030672"(synaptic vesicle membrane)|go:"GO:0035418"(protein localization to synapse)|go:"GO:0043025"(neuronal cell body)|go:"GO:0044306"(neuron projection terminus)|go:"GO:0045202"(synapse)|go:"GO:0045503"(dynein light chain binding)|go:"GO:0046872"(metal ion binding)|go:"GO:0048786"(presynaptic active zone)|go:"GO:0048788"(cytoskeleton of presynaptic active zone)|go:"GO:0050808"(synapse organization)|go:"GO:0060076"(excitatory synapse)|go:"GO:0060077"(inhibitory synapse)|go:"GO:0097470"(ribbon synapse)|go:"GO:0098685"(Schaffer collateral - CA1 synapse)|go:"GO:0098686"(hippocampal mossy fiber to CA3 synapse)|go:"GO:0098693"(regulation of synaptic vesicle cycle)|go:"GO:0098793"(presynapse)|go:"GO:0098831"(presynaptic active zone cytoplasmic component)|go:"GO:0098882"(structural constituent of presynaptic active zone)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0098982"(GABA-ergic synapse)|go:"GO:0099526"(presynapse to nucleus signaling pathway)|go:"GO:1904071"(presynaptic active zone assembly)|go:"GO:1904115"(axon cytoplasm)|go:"GO:1904666"(regulation of ubiquitin protein ligase activity)|go:"GO:1990257"(piccolo-bassoon transport vesicle)	-	-	-	figure legend:ST1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10116(rat-brain-cerebellum)|taxid:10116(Rattus norvegicus)	-	2020/10/30	2020/10/30	rogid:DtE+ZXAZKdCMvUW5K+jXQ5bH07M10116	rogid:7wqEryp1iWbXnosW6KDHacbGxpc10116	rigid:OaXQ9NA25fwCWxejPU3Ao9q5j/E	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q5XIE8	uniprotkb:P30427	intact:EBI-15348306|ensembl:ENSRNOP00000023037	intact:EBI-917155|uniprotkb:O08879|uniprotkb:O08880|uniprotkb:O08881	psi-mi:itm2b_rat(display_long)|uniprotkb:Itm2b(gene name)|psi-mi:Itm2b(display_short)|uniprotkb:Immature BRI2(gene name synonym)|uniprotkb:Transmembrane protein BRI(gene name synonym)	psi-mi:plec_rat(display_long)|uniprotkb:Plec(gene name)|psi-mi:Plec(display_short)|uniprotkb:Plec1(gene name synonym)|uniprotkb:Plectin-1(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Martins et al. (2018)	imex:IM-28469|pubmed:29476059	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26438079|imex:IM-28469-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSRNOG00000016271(gene)|ensembl:ENSRNOT00000023037(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001540"(amyloid-beta binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0010008"(endosome membrane)|go:"GO:0030660"(Golgi-associated vesicle membrane)|go:"GO:0031301"(integral component of organelle membrane)|go:"GO:0042985"(negative regulation of amyloid precursor protein biosynthetic process)|interpro:IPR007084(BRICHOS)|interpro:IPR040145|mint:Q5XIE8|refseq:NP_001006964.1|rgd:620727	interpro:IPR001452(Src homology-3)|interpro:IPR043197|mint:P30427|rgd:621649|interpro:IPR001589(Actinin-type, actin-binding, conserved site)|interpro:IPR001715(Calponin-like actin-binding)|interpro:IPR001101(Plectin repeat)|interpro:IPR005326(Plectin/S10, N-terminal)|interpro:IPR018159|interpro:IPR030269|interpro:IPR036388|interpro:IPR035915|interpro:IPR036872|interpro:IPR041573|interpro:IPR041615|go:"GO:0000902"(cell morphogenesis)|go:"GO:0002162"(dystroglycan binding)|go:"GO:0002522"(leukocyte migration involved in immune response)|go:"GO:0003334"(keratinocyte development)|go:"GO:0003779"(actin binding)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005200"(structural constituent of cytoskeleton)|go:"GO:0005737"(cytoplasm)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005903"(brush border)|go:"GO:0005925"(focal adhesion)|go:"GO:0006469"(negative regulation of protein kinase activity)|go:"GO:0007005"(mitochondrion organization)|go:"GO:0007519"(skeletal muscle tissue development)|go:"GO:0007565"(female pregnancy)|go:"GO:0007584"(response to nutrient)|go:"GO:0008092"(cytoskeletal protein binding)|go:"GO:0008307"(structural constituent of muscle)|go:"GO:0009925"(basal plasma membrane)|go:"GO:0010467"(gene expression)|go:"GO:0010761"(fibroblast migration)|go:"GO:0010818"(T cell chemotaxis)|go:"GO:0014866"(skeletal myofibril assembly)|go:"GO:0016020"(membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0016528"(sarcoplasm)|go:"GO:0019226"(transmission of nerve impulse)|go:"GO:0022011"(myelination in peripheral nervous system)|go:"GO:0030018"(Z disc)|go:"GO:0030036"(actin cytoskeleton organization)|go:"GO:0030056"(hemidesmosome)|go:"GO:0030424"(axon)|go:"GO:0030425"(dendrite)|go:"GO:0030506"(ankyrin binding)|go:"GO:0030855"(epithelial cell differentiation)|go:"GO:0031532"(actin cytoskeleton reorganization)|go:"GO:0031581"(hemidesmosome assembly)|go:"GO:0031668"(cellular response to extracellular stimulus)|go:"GO:0032094"(response to food)|go:"GO:0032287"(peripheral nervous system myelin maintenance)|go:"GO:0034613"(cellular protein localization)|go:"GO:0035264"(multicellular organism growth)|go:"GO:0042060"(wound healing)|go:"GO:0042383"(sarcolemma)|go:"GO:0043034"(costamere)|go:"GO:0043209"(myelin sheath)|go:"GO:0043292"(contractile fiber)|go:"GO:0043588"(skin development)|go:"GO:0043621"(protein self-association)|go:"GO:0043933"(protein-containing complex organization)|go:"GO:0045104"(intermediate filament cytoskeleton organization)|go:"GO:0045109"(intermediate filament organization)|go:"GO:0045214"(sarcomere organization)|go:"GO:0047485"(protein N-terminus binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0048741"(skeletal muscle fiber development)|go:"GO:0048870"(cell motility)|go:"GO:0051015"(actin filament binding)|go:"GO:0055013"(cardiac muscle cell development)|go:"GO:0061436"(establishment of skin barrier)|go:"GO:0070584"(mitochondrion morphogenesis)|go:"GO:0071498"(cellular response to fluid shear stress)|go:"GO:0071944"(cell periphery)|reactome:R-RNO-264870|reactome:R-RNO-446107	-	-	-	figure legend:ST1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10116(rat-brain-cerebellum)|taxid:10116(Rattus norvegicus)	-	2020/10/30	2020/10/30	rogid:DtE+ZXAZKdCMvUW5K+jXQ5bH07M10116	rogid:LQJzfjJNnr1XQnkT1Zv+NvCA71I10116	rigid:OaXQ9NA25fwCWxejPU3Ao9q5j/E	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q5XIE8	uniprotkb:Q62718	intact:EBI-15348306|ensembl:ENSRNOP00000023037	intact:EBI-26437602	psi-mi:itm2b_rat(display_long)|uniprotkb:Itm2b(gene name)|psi-mi:Itm2b(display_short)|uniprotkb:Immature BRI2(gene name synonym)|uniprotkb:Transmembrane protein BRI(gene name synonym)	psi-mi:ntri_rat(display_long)|uniprotkb:Ntm(gene name)|psi-mi:Ntm(display_short)|uniprotkb:Hnt(gene name synonym)|uniprotkb:Nt(gene name synonym)|uniprotkb:GP65(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Martins et al. (2018)	imex:IM-28469|pubmed:29476059	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26438079|imex:IM-28469-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSRNOG00000016271(gene)|ensembl:ENSRNOT00000023037(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001540"(amyloid-beta binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0010008"(endosome membrane)|go:"GO:0030660"(Golgi-associated vesicle membrane)|go:"GO:0031301"(integral component of organelle membrane)|go:"GO:0042985"(negative regulation of amyloid precursor protein biosynthetic process)|interpro:IPR007084(BRICHOS)|interpro:IPR040145|mint:Q5XIE8|refseq:NP_001006964.1|rgd:620727	go:"GO:0005615"(extracellular space)|go:"GO:0005886"(plasma membrane)|go:"GO:0007155"(cell adhesion)|go:"GO:0009986"(cell surface)|go:"GO:0010977"(negative regulation of neuron projection development)|go:"GO:0021549"(cerebellum development)|go:"GO:0030424"(axon)|go:"GO:0031225"(anchored component of membrane)|go:"GO:0032355"(response to estradiol)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0060076"(excitatory synapse)|reactome:R-RNO-163125|mint:Q62718|refseq:NP_059050.1|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR036179|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR013098(Immunoglobulin I-set)|interpro:IPR003599(Immunoglobulin subtype)|interpro:IPR003598(Immunoglobulin subtype 2)|rgd:620958	-	-	-	figure legend:ST1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10116(rat-brain-cerebellum)|taxid:10116(Rattus norvegicus)	-	2020/10/30	2020/10/30	rogid:DtE+ZXAZKdCMvUW5K+jXQ5bH07M10116	rogid:i+PdnqMrxo1FUwJEdO4+27h8qMI10116	rigid:OaXQ9NA25fwCWxejPU3Ao9q5j/E	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q5XIE8	uniprotkb:P12839	intact:EBI-15348306|ensembl:ENSRNOP00000023037	intact:EBI-26373136|uniprotkb:Q63370	psi-mi:itm2b_rat(display_long)|uniprotkb:Itm2b(gene name)|psi-mi:Itm2b(display_short)|uniprotkb:Immature BRI2(gene name synonym)|uniprotkb:Transmembrane protein BRI(gene name synonym)	psi-mi:nfm_rat(display_long)|uniprotkb:160 kDa neurofilament protein(gene name synonym)|uniprotkb:Neurofilament 3(gene name synonym)|uniprotkb:Neurofilament triplet M protein(gene name synonym)|uniprotkb:Nefm(gene name)|psi-mi:Nefm(display_short)|uniprotkb:Nef3(gene name synonym)|uniprotkb:Nfm(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Martins et al. (2018)	imex:IM-28469|pubmed:29476059	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26438079|imex:IM-28469-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSRNOG00000016271(gene)|ensembl:ENSRNOT00000023037(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001540"(amyloid-beta binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0010008"(endosome membrane)|go:"GO:0030660"(Golgi-associated vesicle membrane)|go:"GO:0031301"(integral component of organelle membrane)|go:"GO:0042985"(negative regulation of amyloid precursor protein biosynthetic process)|interpro:IPR007084(BRICHOS)|interpro:IPR040145|mint:Q5XIE8|refseq:NP_001006964.1|rgd:620727	go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005882"(intermediate filament)|go:"GO:0005883"(neurofilament)|go:"GO:0008088"(axo-dendritic transport)|go:"GO:0014069"(postsynaptic density)|go:"GO:0015643"(toxic substance binding)|go:"GO:0021510"(spinal cord development)|go:"GO:0021766"(hippocampus development)|go:"GO:0021987"(cerebral cortex development)|go:"GO:0030424"(axon)|go:"GO:0031133"(regulation of axon diameter)|go:"GO:0031594"(neuromuscular junction)|go:"GO:0033693"(neurofilament bundle assembly)|go:"GO:0034599"(cellular response to oxidative stress)|go:"GO:0043005"(neuron projection)|go:"GO:0043204"(perikaryon)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045104"(intermediate filament cytoskeleton organization)|go:"GO:0045105"(intermediate filament polymerization or depolymerization)|go:"GO:0045110"(intermediate filament bundle assembly)|go:"GO:0060052"(neurofilament cytoskeleton organization)|go:"GO:0071392"(cellular response to estradiol stimulus)|go:"GO:0097418"(neurofibrillary tangle)|go:"GO:0099160"(postsynaptic intermediate filament cytoskeleton)|go:"GO:0099182"(presynaptic intermediate filament cytoskeleton)|go:"GO:1903937"(response to acrylamide)|interpro:IPR002957(Keratin, type I)|interpro:IPR006821(Intermediate filament, DNA-binding region)|interpro:IPR018039|interpro:IPR027697|interpro:IPR039008|go:"GO:0031103"(axon regeneration)|dip:DIP-208N|rgd:3160|mint:P12839|refseq:NP_058725.1	-	-	-	figure legend:ST1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10116(rat-brain-cerebellum)|taxid:10116(Rattus norvegicus)	-	2020/10/30	2020/10/30	rogid:DtE+ZXAZKdCMvUW5K+jXQ5bH07M10116	rogid:WTqdAIK26RRBJSPTeEifkRwfgXM10116	rigid:OaXQ9NA25fwCWxejPU3Ao9q5j/E	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q5XIE8	uniprotkb:Q5RJQ4	intact:EBI-15348306|ensembl:ENSRNOP00000023037	intact:EBI-2696664|ensembl:ENSRNOP00000059450	psi-mi:itm2b_rat(display_long)|uniprotkb:Itm2b(gene name)|psi-mi:Itm2b(display_short)|uniprotkb:Immature BRI2(gene name synonym)|uniprotkb:Transmembrane protein BRI(gene name synonym)	psi-mi:sir2_rat(display_long)|uniprotkb:Sirt2(gene name)|psi-mi:Sirt2(display_short)|uniprotkb:Sir2l2(gene name synonym)|uniprotkb:SIR2-like protein 2(gene name synonym)|uniprotkb:Regulatory protein SIR2 homolog 2(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Martins et al. (2018)	imex:IM-28469|pubmed:29476059	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26438079|imex:IM-28469-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSRNOG00000016271(gene)|ensembl:ENSRNOT00000023037(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001540"(amyloid-beta binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0010008"(endosome membrane)|go:"GO:0030660"(Golgi-associated vesicle membrane)|go:"GO:0031301"(integral component of organelle membrane)|go:"GO:0042985"(negative regulation of amyloid precursor protein biosynthetic process)|interpro:IPR007084(BRICHOS)|interpro:IPR040145|mint:Q5XIE8|refseq:NP_001006964.1|rgd:620727	rgd:621481|refseq:NP_001008369.1|ensembl:ENSRNOG00000020102(gene)|ensembl:ENSRNOT00000064153(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000792"(heterochromatin)|go:"GO:0003682"(chromatin binding)|go:"GO:0003950"(NAD+ ADP-ribosyltransferase activity)|go:"GO:0004407"(histone deacetylase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005694"(chromosome)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005813"(centrosome)|go:"GO:0005814"(centriole)|go:"GO:0005819"(spindle)|go:"GO:0005829"(cytosol)|go:"GO:0005874"(microtubule)|go:"GO:0005886"(plasma membrane)|go:"GO:0006471"(protein ADP-ribosylation)|go:"GO:0006476"(protein deacetylation)|go:"GO:0006914"(autophagy)|go:"GO:0007417"(central nervous system development)|go:"GO:0008270"(zinc ion binding)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0010507"(negative regulation of autophagy)|go:"GO:0010801"(negative regulation of peptidyl-threonine phosphorylation)|go:"GO:0014065"(phosphatidylinositol 3-kinase signaling)|go:"GO:0016575"(histone deacetylation)|go:"GO:0017136"(NAD-dependent histone deacetylase activity)|go:"GO:0022011"(myelination in peripheral nervous system)|go:"GO:0030426"(growth cone)|go:"GO:0030496"(midbody)|go:"GO:0031641"(regulation of myelination)|go:"GO:0032436"(positive regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0033010"(paranodal junction)|go:"GO:0033270"(paranode region of axon)|go:"GO:0033558"(protein deacetylase activity)|go:"GO:0034599"(cellular response to oxidative stress)|go:"GO:0034979"(NAD-dependent protein deacetylase activity)|go:"GO:0034983"(peptidyl-lysine deacetylation)|go:"GO:0035035"(histone acetyltransferase binding)|go:"GO:0035729"(cellular response to hepatocyte growth factor stimulus)|go:"GO:0035748"(myelin sheath abaxonal region)|go:"GO:0042177"(negative regulation of protein catabolic process)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0042903"(tubulin deacetylase activity)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043130"(ubiquitin binding)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0043204"(perikaryon)|go:"GO:0043209"(myelin sheath)|go:"GO:0043219"(lateral loop)|go:"GO:0043220"(Schmidt-Lanterman incisure)|go:"GO:0043388"(positive regulation of DNA binding)|go:"GO:0043491"(protein kinase B signaling)|go:"GO:0044224"(juxtaparanode region of axon)|go:"GO:0044242"(cellular lipid catabolic process)|go:"GO:0045598"(regulation of fat cell differentiation)|go:"GO:0045599"(negative regulation of fat cell differentiation)|go:"GO:0045836"(positive regulation of meiotic nuclear division)|go:"GO:0045843"(negative regulation of striated muscle tissue development)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046970"("NAD-dependent histone deacetylase activity (H4-K16 specific)")|go:"GO:0048012"(hepatocyte growth factor receptor signaling pathway)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0048487"(beta-tubulin binding)|go:"GO:0048715"(negative regulation of oligodendrocyte differentiation)|go:"GO:0051301"(cell division)|go:"GO:0051321"(meiotic cell cycle)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0051781"(positive regulation of cell division)|go:"GO:0051987"(positive regulation of attachment of spindle microtubules to kinetochore)|go:"GO:0061428"(negative regulation of transcription from RNA polymerase II promoter in response to hypoxia)|go:"GO:0061433"(cellular response to caloric restriction)|go:"GO:0070403"(NAD+ binding)|go:"GO:0070446"(negative regulation of oligodendrocyte progenitor proliferation)|go:"GO:0070932"(histone H3 deacetylation)|go:"GO:0070933"(histone H4 deacetylation)|go:"GO:0071219"(cellular response to molecule of bacterial origin)|go:"GO:0071456"(cellular response to hypoxia)|go:"GO:0071872"(cellular response to epinephrine stimulus)|go:"GO:0072686"(mitotic spindle)|go:"GO:0072687"(meiotic spindle)|go:"GO:0090042"(tubulin deacetylation)|go:"GO:0097386"(glial cell projection)|go:"GO:0097456"(terminal loop)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099149"(regulation of postsynaptic neurotransmitter receptor internalization)|go:"GO:1900119"(positive regulation of execution phase of apoptosis)|go:"GO:1900195"(positive regulation of oocyte maturation)|go:"GO:1900226"(negative regulation of NLRP3 inflammasome complex assembly)|go:"GO:1900425"(negative regulation of defense response to bacterium)|go:"GO:2000378"(negative regulation of reactive oxygen species metabolic process)|go:"GO:2000777"(positive regulation of proteasomal ubiquitin-dependent protein catabolic process involved in cellular response to hypoxia)|interpro:IPR003000(NAD-dependent histone deacetylase, silent information regulator Sir2)|interpro:IPR017328(NAD-dependent deacetylase sirtuin-2, eukaryota)|interpro:IPR026590|interpro:IPR026591|interpro:IPR029035|mint:Q5RJQ4|reactome:R-RNO-2995383	-	-	-	figure legend:ST1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10116(rat-brain-cerebellum)|taxid:10116(Rattus norvegicus)	-	2020/10/30	2020/10/30	rogid:DtE+ZXAZKdCMvUW5K+jXQ5bH07M10116	rogid:yxpJ/hJp1J7pE2ctnECN4j+HkoA10116	rigid:OaXQ9NA25fwCWxejPU3Ao9q5j/E	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q5XIE8	uniprotkb:Q62812	intact:EBI-15348306|ensembl:ENSRNOP00000023037	intact:EBI-5747325	psi-mi:itm2b_rat(display_long)|uniprotkb:Itm2b(gene name)|psi-mi:Itm2b(display_short)|uniprotkb:Immature BRI2(gene name synonym)|uniprotkb:Transmembrane protein BRI(gene name synonym)	psi-mi:myh9_rat(display_long)|uniprotkb:Myh9(gene name)|psi-mi:Myh9(display_short)|uniprotkb:Cellular myosin heavy chain, type A(gene name synonym)|uniprotkb:Myosin heavy chain 9(gene name synonym)|uniprotkb:Myosin heavy chain, non-muscle IIa(gene name synonym)|uniprotkb:Non-muscle myosin heavy chain A(gene name synonym)|uniprotkb:Non-muscle myosin heavy chain IIa(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Martins et al. (2018)	imex:IM-28469|pubmed:29476059	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26438079|imex:IM-28469-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSRNOG00000016271(gene)|ensembl:ENSRNOT00000023037(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001540"(amyloid-beta binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0010008"(endosome membrane)|go:"GO:0030660"(Golgi-associated vesicle membrane)|go:"GO:0031301"(integral component of organelle membrane)|go:"GO:0042985"(negative regulation of amyloid precursor protein biosynthetic process)|interpro:IPR007084(BRICHOS)|interpro:IPR040145|mint:Q5XIE8|refseq:NP_001006964.1|rgd:620727	rgd:3140|interpro:IPR000048(IQ calmodulin-binding region)|interpro:IPR001609(Myosin head, motor region)|interpro:IPR004009(Myosin, N-terminal, SH3-like)|interpro:IPR002928(Myosin tail)|interpro:IPR008989(Myosin S1 fragment, N-terminal)|interpro:IPR036961|mint:Q62812|interpro:IPR027417|go:"GO:0000146"(microfilament motor activity)|go:"GO:0000212"(meiotic spindle organization)|go:"GO:0000904"(cell morphogenesis involved in differentiation)|go:"GO:0001525"(angiogenesis)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0001725"(stress fiber)|go:"GO:0001726"(ruffle)|go:"GO:0001768"(establishment of T cell polarity)|go:"GO:0001772"(immunological synapse)|go:"GO:0001778"(plasma membrane repair)|go:"GO:0001931"(uropod)|go:"GO:0001965"(G-protein alpha-subunit binding)|go:"GO:0003779"(actin binding)|go:"GO:0005178"(integrin binding)|go:"GO:0005391"("P-type sodium:potassium-exchanging transporter activity")|go:"GO:0005516"(calmodulin binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005819"(spindle)|go:"GO:0005826"(actomyosin contractile ring)|go:"GO:0005829"(cytosol)|go:"GO:0005884"(actin filament)|go:"GO:0005886"(plasma membrane)|go:"GO:0005903"(brush border)|go:"GO:0005912"(adherens junction)|go:"GO:0005938"(cell cortex)|go:"GO:0006509"(membrane protein ectodomain proteolysis)|go:"GO:0006911"(phagocytosis, engulfment)|go:"GO:0007155"(cell adhesion)|go:"GO:0007520"(myoblast fusion)|go:"GO:0008360"(regulation of cell shape)|go:"GO:0009898"(cytoplasmic side of plasma membrane)|go:"GO:0015031"(protein transport)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0016328"(lateral plasma membrane)|go:"GO:0016459"(myosin complex)|go:"GO:0016460"(myosin II complex)|go:"GO:0016887"(ATP hydrolysis activity)|go:"GO:0019901"(protein kinase binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030027"(lamellipodium)|go:"GO:0030048"(actin filament-based movement)|go:"GO:0030220"(platelet formation)|go:"GO:0030224"(monocyte differentiation)|go:"GO:0030863"(cortical cytoskeleton)|go:"GO:0031032"(actomyosin structure organization)|go:"GO:0031252"(cell leading edge)|go:"GO:0031532"(actin cytoskeleton reorganization)|go:"GO:0031594"(neuromuscular junction)|go:"GO:0031762"(follicle-stimulating hormone receptor binding)|go:"GO:0032154"(cleavage furrow)|go:"GO:0032418"(lysosome localization)|go:"GO:0032506"(cytokinetic process)|go:"GO:0032796"(uropod organization)|go:"GO:0032962"(positive regulation of inositol trisphosphate biosynthetic process)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035774"(positive regulation of insulin secretion involved in cellular response to glucose stimulus)|go:"GO:0036120"(cellular response to platelet-derived growth factor stimulus)|go:"GO:0042641"(actomyosin)|go:"GO:0042699"(follicle-stimulating hormone signaling pathway)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043495"(protein-membrane adaptor activity)|go:"GO:0043531"(ADP binding)|go:"GO:0043534"(blood vessel endothelial cell migration)|go:"GO:0045055"(regulated exocytosis)|go:"GO:0045745"(positive regulation of G protein-coupled receptor signaling pathway)|go:"GO:0045807"(positive regulation of endocytosis)|go:"GO:0050766"(positive regulation of phagocytosis)|go:"GO:0051015"(actin filament binding)|go:"GO:0051017"(actin filament bundle assembly)|go:"GO:0051295"(establishment of meiotic spindle localization)|go:"GO:0051482"(positive regulation of cytosolic calcium ion concentration involved in phospholipase C-activating G protein-coupled signaling pathway)|go:"GO:0051894"(positive regulation of focal adhesion assembly)|go:"GO:0060471"(cortical granule exocytosis)|go:"GO:0060473"(cortical granule)|go:"GO:0070374"(positive regulation of ERK1 and ERK2 cascade)|go:"GO:0070650"(actin filament bundle distribution)|go:"GO:0071260"(cellular response to mechanical stimulus)|go:"GO:0097110"(scaffold protein binding)|go:"GO:0097513"(myosin II filament)|go:"GO:0098609"(cell-cell adhesion)|go:"GO:1903919"(negative regulation of actin filament severing)|go:"GO:1903923"(positive regulation of protein processing in phagocytic vesicle)|go:"GO:1904753"(negative regulation of vascular associated smooth muscle cell migration)|go:"GO:1905684"(regulation of plasma membrane repair)|reactome:R-RNO-2029482|reactome:R-RNO-5627123	-	-	-	figure legend:ST1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10116(rat-brain-cerebellum)|taxid:10116(Rattus norvegicus)	-	2020/10/30	2020/10/30	rogid:DtE+ZXAZKdCMvUW5K+jXQ5bH07M10116	rogid:6JXGCXNFsQdsUBb5t+ubhweRA8Y10116	rigid:OaXQ9NA25fwCWxejPU3Ao9q5j/E	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q5XIE8	uniprotkb:Q9JLT0	intact:EBI-15348306|ensembl:ENSRNOP00000023037	intact:EBI-26373055	psi-mi:itm2b_rat(display_long)|uniprotkb:Itm2b(gene name)|psi-mi:Itm2b(display_short)|uniprotkb:Immature BRI2(gene name synonym)|uniprotkb:Transmembrane protein BRI(gene name synonym)	psi-mi:myh10_rat(display_long)|uniprotkb:Cellular myosin heavy chain, type B(gene name synonym)|uniprotkb:Myosin heavy chain 10(gene name synonym)|uniprotkb:Myosin heavy chain, non-muscle IIb(gene name synonym)|uniprotkb:Non-muscle myosin heavy chain B(gene name synonym)|uniprotkb:Non-muscle myosin heavy chain IIb(gene name synonym)|uniprotkb:Myh10(gene name)|psi-mi:Myh10(display_short)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Martins et al. (2018)	imex:IM-28469|pubmed:29476059	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26438079|imex:IM-28469-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSRNOG00000016271(gene)|ensembl:ENSRNOT00000023037(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001540"(amyloid-beta binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0010008"(endosome membrane)|go:"GO:0030660"(Golgi-associated vesicle membrane)|go:"GO:0031301"(integral component of organelle membrane)|go:"GO:0042985"(negative regulation of amyloid precursor protein biosynthetic process)|interpro:IPR007084(BRICHOS)|interpro:IPR040145|mint:Q5XIE8|refseq:NP_001006964.1|rgd:620727	go:"GO:0007097"(nuclear migration)|go:"GO:0007155"(cell adhesion)|go:"GO:0007409"(axonogenesis)|go:"GO:0007411"(axon guidance)|go:"GO:0007420"(brain development)|go:"GO:0007507"(heart development)|go:"GO:0007512"(adult heart development)|go:"GO:0008283"(cell population proliferation)|go:"GO:0008360"(regulation of cell shape)|go:"GO:0009898"(cytoplasmic side of plasma membrane)|go:"GO:0016459"(myosin complex)|go:"GO:0016460"(myosin II complex)|go:"GO:0021592"(fourth ventricle development)|go:"GO:0021670"(lateral ventricle development)|go:"GO:0021678"(third ventricle development)|go:"GO:0021680"(cerebellar Purkinje cell layer development)|go:"GO:0006930"(substrate-dependent cell migration, cell extension)|go:"GO:0030036"(actin cytoskeleton organization)|go:"GO:0030048"(actin filament-based movement)|go:"GO:0030239"(myofibril assembly)|go:"GO:0030424"(axon)|go:"GO:0030426"(growth cone)|go:"GO:0030496"(midbody)|go:"GO:0031032"(actomyosin structure organization)|go:"GO:0031175"(neuron projection development)|go:"GO:0031594"(neuromuscular junction)|go:"GO:0032154"(cleavage furrow)|go:"GO:0035613"(RNA stem-loop binding)|go:"GO:0035904"(aorta development)|go:"GO:0042641"(actomyosin)|go:"GO:0042802"(identical protein binding)|go:"GO:0043005"(neuron projection)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043197"(dendritic spine)|go:"GO:0043531"(ADP binding)|go:"GO:0048027"(mRNA 5'-UTR binding)|go:"GO:0050714"(positive regulation of protein secretion)|go:"GO:0050885"(neuromuscular process controlling balance)|go:"GO:0051015"(actin filament binding)|go:"GO:0051017"(actin filament bundle assembly)|go:"GO:0055003"(cardiac myofibril assembly)|go:"GO:0055015"(ventricular cardiac muscle cell development)|go:"GO:0060041"(retina development in camera-type eye)|go:"GO:0060976"(coronary vasculature development)|go:"GO:0030027"(lamellipodium)|go:"GO:0070650"(actin filament bundle distribution)|go:"GO:0097513"(myosin II filament)|go:"GO:0098871"(postsynaptic actin cytoskeleton)|go:"GO:0098974"(postsynaptic actin cytoskeleton organization)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:1905274"(regulation of modification of postsynaptic actin cytoskeleton)|reactome:R-RNO-5627123|go:"GO:0000146"(microfilament motor activity)|go:"GO:0000281"(mitotic cytokinesis)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0001725"(stress fiber)|go:"GO:0001764"(neuron migration)|go:"GO:0001778"(plasma membrane repair)|go:"GO:0003279"(cardiac septum development)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005819"(spindle)|go:"GO:0005829"(cytosol)|go:"GO:0005844"(polysome)|go:"GO:0005903"(brush border)|go:"GO:0005938"(cell cortex)|go:"GO:0006887"(exocytosis)|rgd:71000|mint:Q9JLT0|interpro:IPR000048(IQ calmodulin-binding region)|interpro:IPR036961|interpro:IPR001609(Myosin head, motor region)|interpro:IPR004009(Myosin, N-terminal, SH3-like)|interpro:IPR008989(Myosin S1 fragment, N-terminal)|interpro:IPR002928(Myosin tail)|interpro:IPR027417|refseq:NP_113708.1	-	-	-	figure legend:ST1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10116(rat-brain-cerebellum)|taxid:10116(Rattus norvegicus)	-	2020/10/30	2020/10/30	rogid:DtE+ZXAZKdCMvUW5K+jXQ5bH07M10116	rogid:A2Z4b2T6i49aTpwnqohYbOIrw7M10116	rigid:OaXQ9NA25fwCWxejPU3Ao9q5j/E	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q5XIE8	uniprotkb:P13832	intact:EBI-15348306|ensembl:ENSRNOP00000023037	intact:EBI-21297735|ensembl:ENSRNOP00000021048	psi-mi:itm2b_rat(display_long)|uniprotkb:Itm2b(gene name)|psi-mi:Itm2b(display_short)|uniprotkb:Immature BRI2(gene name synonym)|uniprotkb:Transmembrane protein BRI(gene name synonym)	psi-mi:mrlca_rat(display_long)|uniprotkb:Rlc-a(gene name)|psi-mi:Rlc-a(display_short)|uniprotkb:Myosin regulatory light chain 2-A, smooth muscle isoform(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Martins et al. (2018)	imex:IM-28469|pubmed:29476059	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26438079|imex:IM-28469-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSRNOG00000016271(gene)|ensembl:ENSRNOT00000023037(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001540"(amyloid-beta binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0010008"(endosome membrane)|go:"GO:0030660"(Golgi-associated vesicle membrane)|go:"GO:0031301"(integral component of organelle membrane)|go:"GO:0042985"(negative regulation of amyloid precursor protein biosynthetic process)|interpro:IPR007084(BRICHOS)|interpro:IPR040145|mint:Q5XIE8|refseq:NP_001006964.1|rgd:620727	ensembl:ENSRNOG00000015278(gene)|ensembl:ENSRNOT00000021048(transcript)|go:"GO:0001725"(stress fiber)|go:"GO:0005509"(calcium ion binding)|go:"GO:0008360"(regulation of cell shape)|go:"GO:0016460"(myosin II complex)|go:"GO:0030018"(Z disc)|go:"GO:0035254"(glutamate receptor binding)|go:"GO:0072659"(protein localization to plasma membrane)|interpro:IPR002048(Calcium-binding EF-hand)|interpro:IPR011992(EF-Hand type)|interpro:IPR018247|mint:P13832|reactome:R-RNO-3928664|reactome:R-RNO-445355|refseq:NP_001128489.1|refseq:XP_006245730.1	-	-	-	figure legend:ST1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10116(rat-brain-cerebellum)|taxid:10116(Rattus norvegicus)	-	2020/10/30	2020/10/30	rogid:DtE+ZXAZKdCMvUW5K+jXQ5bH07M10116	rogid:4E6Q/Ilwmfu3aaQ8ArPbEd6jCYs10116	rigid:OaXQ9NA25fwCWxejPU3Ao9q5j/E	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q5XIE8	uniprotkb:Q63345	intact:EBI-15348306|ensembl:ENSRNOP00000023037	intact:EBI-26437576	psi-mi:itm2b_rat(display_long)|uniprotkb:Itm2b(gene name)|psi-mi:Itm2b(display_short)|uniprotkb:Immature BRI2(gene name synonym)|uniprotkb:Transmembrane protein BRI(gene name synonym)	psi-mi:mog_rat(display_long)|uniprotkb:Mog(gene name)|psi-mi:Mog(display_short)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Martins et al. (2018)	imex:IM-28469|pubmed:29476059	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26438079|imex:IM-28469-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSRNOG00000016271(gene)|ensembl:ENSRNOT00000023037(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001540"(amyloid-beta binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0010008"(endosome membrane)|go:"GO:0030660"(Golgi-associated vesicle membrane)|go:"GO:0031301"(integral component of organelle membrane)|go:"GO:0042985"(negative regulation of amyloid precursor protein biosynthetic process)|interpro:IPR007084(BRICHOS)|interpro:IPR040145|mint:Q5XIE8|refseq:NP_001006964.1|rgd:620727	go:"GO:0001817"(regulation of cytokine production)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0007155"(cell adhesion)|go:"GO:0007568"(aging)|go:"GO:0009897"(external side of plasma membrane)|go:"GO:0009986"(cell surface)|go:"GO:0016021"(integral component of membrane)|go:"GO:0033993"(response to lipid)|go:"GO:0043209"(myelin sheath)|go:"GO:0045121"(membrane raft)|go:"GO:0050852"(T cell receptor signaling pathway)|go:"GO:0051593"(response to folic acid)|rcsb pdb:1PKO|rcsb pdb:1PKQ|rcsb pdb:3CSP|mint:Q63345|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR036179|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR003599(Immunoglobulin subtype)|interpro:IPR013106(Immunoglobulin V-set)|interpro:IPR016663(Myelin-oligodendrocyte glycoprotein)|rgd:3102	-	-	-	figure legend:ST1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10116(rat-brain-cerebellum)|taxid:10116(Rattus norvegicus)	-	2020/10/30	2020/10/30	rogid:DtE+ZXAZKdCMvUW5K+jXQ5bH07M10116	rogid:Xwqfja7qnPwG/22GvWV7ODGhbGU10116	rigid:OaXQ9NA25fwCWxejPU3Ao9q5j/E	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q5XIE8	uniprotkb:P07722	intact:EBI-15348306|ensembl:ENSRNOP00000023037	intact:EBI-26373743|ensembl:ENSRNOP00000028544|uniprotkb:P02685|uniprotkb:P07723	psi-mi:itm2b_rat(display_long)|uniprotkb:Itm2b(gene name)|psi-mi:Itm2b(display_short)|uniprotkb:Immature BRI2(gene name synonym)|uniprotkb:Transmembrane protein BRI(gene name synonym)	psi-mi:mag_rat(display_long)|uniprotkb:1B236(gene name synonym)|uniprotkb:Brain neuron cytoplasmic protein 3(gene name synonym)|uniprotkb:Sialic acid-binding Ig-like lectin 4a(gene name synonym)|uniprotkb:Mag(gene name)|psi-mi:Mag(display_short)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Martins et al. (2018)	imex:IM-28469|pubmed:29476059	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26438079|imex:IM-28469-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSRNOG00000016271(gene)|ensembl:ENSRNOT00000023037(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001540"(amyloid-beta binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0010008"(endosome membrane)|go:"GO:0030660"(Golgi-associated vesicle membrane)|go:"GO:0031301"(integral component of organelle membrane)|go:"GO:0042985"(negative regulation of amyloid precursor protein biosynthetic process)|interpro:IPR007084(BRICHOS)|interpro:IPR040145|mint:Q5XIE8|refseq:NP_001006964.1|rgd:620727	interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR036179|mint:P07722|reactome:R-RNO-193634|reactome:R-RNO-210991|ensembl:ENSRNOG00000021023(gene)|ensembl:ENSRNOT00000028544(transcript)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0007155"(cell adhesion)|go:"GO:0007399"(nervous system development)|go:"GO:0010977"(negative regulation of neuron projection development)|go:"GO:0019226"(transmission of nerve impulse)|go:"GO:0019901"(protein kinase binding)|go:"GO:0022010"(central nervous system myelination)|go:"GO:0030246"(carbohydrate binding)|go:"GO:0030517"(negative regulation of axon extension)|go:"GO:0031103"(axon regeneration)|go:"GO:0031643"(positive regulation of myelination)|go:"GO:0033691"(sialic acid binding)|go:"GO:0035749"(myelin sheath adaxonal region)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043209"(myelin sheath)|go:"GO:0043218"(compact myelin)|go:"GO:0043220"(Schmidt-Lanterman incisure)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0045121"(membrane raft)|go:"GO:0045665"(negative regulation of neuron differentiation)|go:"GO:0048711"(positive regulation of astrocyte differentiation)|go:"GO:0071260"(cellular response to mechanical stimulus)|go:"GO:0097453"(mesaxon)|go:"GO:0098742"(cell-cell adhesion via plasma-membrane adhesion molecules)|go:"GO:1905576"(ganglioside GT1b binding)|interpro:IPR003598(Immunoglobulin subtype 2)|interpro:IPR003599(Immunoglobulin subtype)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR013162(CD80-like, immunoglobulin C2-set)|go:"GO:0033270"(paranode region of axon)|rgd:3035|refseq:NP_058886.1|refseq:XP_006228886.1|refseq:XP_008757360.1|refseq:XP_017444540.1|refseq:XP_017444541.1|refseq:XP_017444542.1	-	-	-	figure legend:ST1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10116(rat-brain-cerebellum)|taxid:10116(Rattus norvegicus)	-	2020/10/30	2020/10/30	rogid:DtE+ZXAZKdCMvUW5K+jXQ5bH07M10116	rogid:WjoXy9hFKXqk5kuzguBEIx7yGIc10116	rigid:OaXQ9NA25fwCWxejPU3Ao9q5j/E	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q5XIE8	uniprotkb:P60203	intact:EBI-15348306|ensembl:ENSRNOP00000023037	intact:EBI-8848294|uniprotkb:P04400|uniprotkb:P06905|uniprotkb:Q561K5|ensembl:ENSRNOP00000003283	psi-mi:itm2b_rat(display_long)|uniprotkb:Itm2b(gene name)|psi-mi:Itm2b(display_short)|uniprotkb:Immature BRI2(gene name synonym)|uniprotkb:Transmembrane protein BRI(gene name synonym)	psi-mi:mypr_rat(display_long)|uniprotkb:Plp1(gene name)|psi-mi:Plp1(display_short)|uniprotkb:Plp(gene name synonym)|uniprotkb:Lipophilin(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Martins et al. (2018)	imex:IM-28469|pubmed:29476059	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26438079|imex:IM-28469-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSRNOG00000016271(gene)|ensembl:ENSRNOT00000023037(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001540"(amyloid-beta binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0010008"(endosome membrane)|go:"GO:0030660"(Golgi-associated vesicle membrane)|go:"GO:0031301"(integral component of organelle membrane)|go:"GO:0042985"(negative regulation of amyloid precursor protein biosynthetic process)|interpro:IPR007084(BRICHOS)|interpro:IPR040145|mint:Q5XIE8|refseq:NP_001006964.1|rgd:620727	refseq:XP_017457402.1|refseq:NP_112252.1|rgd:3354|ensembl:ENSRNOG00000002419(gene)|ensembl:ENSRNOT00000003283(transcript)|go:"GO:0005886"(plasma membrane)|go:"GO:0006954"(inflammatory response)|go:"GO:0008366"(axon ensheathment)|go:"GO:0010001"(glial cell differentiation)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0014002"(astrocyte development)|go:"GO:0019911"(structural constituent of myelin sheath)|go:"GO:0022010"(central nervous system myelination)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0031175"(neuron projection development)|go:"GO:0034683"(integrin alphav-beta3 complex)|go:"GO:0042552"(myelination)|go:"GO:0042759"(long-chain fatty acid biosynthetic process)|go:"GO:0043209"(myelin sheath)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0061564"(axon development)|go:"GO:0098990"(AMPA selective glutamate receptor signaling pathway)|go:"GO:1904427"(positive regulation of calcium ion transmembrane transport)|interpro:IPR001614(Myelin proteolipid protein PLP)|interpro:IPR018237|mint:P60203	-	-	-	figure legend:ST1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10116(rat-brain-cerebellum)|taxid:10116(Rattus norvegicus)	-	2020/10/30	2020/10/30	rogid:DtE+ZXAZKdCMvUW5K+jXQ5bH07M10116	rogid:b7pt7FJVt10Iu1tTMeiVYEu5r/k10116	rigid:OaXQ9NA25fwCWxejPU3Ao9q5j/E	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q5XIE8	uniprotkb:D3ZHV2	intact:EBI-15348306|ensembl:ENSRNOP00000023037	intact:EBI-26437518	psi-mi:itm2b_rat(display_long)|uniprotkb:Itm2b(gene name)|psi-mi:Itm2b(display_short)|uniprotkb:Immature BRI2(gene name synonym)|uniprotkb:Transmembrane protein BRI(gene name synonym)	psi-mi:macf1_rat(display_long)|uniprotkb:Macf1(gene name)|psi-mi:Macf1(display_short)|uniprotkb:Acf7(gene name synonym)|uniprotkb:Aclp7(gene name synonym)|uniprotkb:Macf(gene name synonym)|uniprotkb:Actin cross-linking family 7(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Martins et al. (2018)	imex:IM-28469|pubmed:29476059	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26438079|imex:IM-28469-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSRNOG00000016271(gene)|ensembl:ENSRNOT00000023037(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001540"(amyloid-beta binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0010008"(endosome membrane)|go:"GO:0030660"(Golgi-associated vesicle membrane)|go:"GO:0031301"(integral component of organelle membrane)|go:"GO:0042985"(negative regulation of amyloid precursor protein biosynthetic process)|interpro:IPR007084(BRICHOS)|interpro:IPR040145|mint:Q5XIE8|refseq:NP_001006964.1|rgd:620727	go:"GO:0150011"(regulation of neuron projection arborization)|go:"GO:0001707"(mesoderm formation)|go:"GO:0003779"(actin binding)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005874"(microtubule)|go:"GO:0005886"(plasma membrane)|go:"GO:0006620"(posttranslational protein targeting to endoplasmic reticulum membrane)|go:"GO:0007163"(establishment or maintenance of cell polarity)|go:"GO:0008017"(microtubule binding)|go:"GO:0010632"(regulation of epithelial cell migration)|go:"GO:0014069"(postsynaptic density)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0016020"(membrane)|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0030177"(positive regulation of Wnt signaling pathway)|go:"GO:0030334"(regulation of cell migration)|go:"GO:0032587"(ruffle membrane)|go:"GO:0032886"(regulation of microtubule-based process)|go:"GO:0042060"(wound healing)|go:"GO:0043001"(Golgi to plasma membrane protein transport)|go:"GO:0045104"(intermediate filament cytoskeleton organization)|go:"GO:0045773"(positive regulation of axon extension)|go:"GO:0051011"(microtubule minus-end binding)|go:"GO:0051015"(actin filament binding)|go:"GO:0051893"(regulation of focal adhesion assembly)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|mint:D3ZHV2|refseq:XP_017448990.1|interpro:IPR001589(Actinin-type, actin-binding, conserved site)|interpro:IPR001715(Calponin-like actin-binding)|interpro:IPR036872|interpro:IPR041615|interpro:IPR041573|interpro:IPR011992(EF-Hand type)|interpro:IPR018247|interpro:IPR002048(Calcium-binding EF-hand)|interpro:IPR003108(Growth-arrest-specific protein 2)|interpro:IPR036534|interpro:IPR043197|interpro:IPR001452(Src homology-3)|interpro:IPR018159|interpro:IPR002017(Spectrin repeat)|rgd:1306057	-	-	-	figure legend:ST1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10116(rat-brain-cerebellum)|taxid:10116(Rattus norvegicus)	-	2020/10/30	2020/10/30	rogid:DtE+ZXAZKdCMvUW5K+jXQ5bH07M10116	rogid:z44YaT5kXMwxgUqKagQIR8nZzug10116	rigid:OaXQ9NA25fwCWxejPU3Ao9q5j/E	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q5XIE8	uniprotkb:D4A7N1	intact:EBI-15348306|ensembl:ENSRNOP00000023037	intact:EBI-26437502|ensembl:ENSRNOP00000073575	psi-mi:itm2b_rat(display_long)|uniprotkb:Itm2b(gene name)|psi-mi:Itm2b(display_short)|uniprotkb:Immature BRI2(gene name synonym)|uniprotkb:Transmembrane protein BRI(gene name synonym)	psi-mi:mic25_rat(display_long)|uniprotkb:Chchd6(gene name)|psi-mi:Chchd6(display_short)|uniprotkb:Mic25(gene name synonym)|uniprotkb:Coiled-coil-helix-coiled-coil-helix domain-containing protein 6(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Martins et al. (2018)	imex:IM-28469|pubmed:29476059	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26438079|imex:IM-28469-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSRNOG00000016271(gene)|ensembl:ENSRNOT00000023037(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001540"(amyloid-beta binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0010008"(endosome membrane)|go:"GO:0030660"(Golgi-associated vesicle membrane)|go:"GO:0031301"(integral component of organelle membrane)|go:"GO:0042985"(negative regulation of amyloid precursor protein biosynthetic process)|interpro:IPR007084(BRICHOS)|interpro:IPR040145|mint:Q5XIE8|refseq:NP_001006964.1|rgd:620727	ensembl:ENSRNOG00000060248(gene)|ensembl:ENSRNOT00000088753(transcript)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005829"(cytosol)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0042407"(cristae formation)|go:"GO:0061617"(MICOS complex)|interpro:IPR042860|mint:D4A7N1|refseq:NP_001100078.1|rgd:1304561	-	-	-	figure legend:ST1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10116(rat-brain-cerebellum)|taxid:10116(Rattus norvegicus)	-	2020/10/30	2020/10/30	rogid:DtE+ZXAZKdCMvUW5K+jXQ5bH07M10116	rogid:jjViah3UrbBOjNpCuJ9AICI4vmE10116	rigid:OaXQ9NA25fwCWxejPU3Ao9q5j/E	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q5XIE8	uniprotkb:Q62813	intact:EBI-15348306|ensembl:ENSRNOP00000023037	intact:EBI-26437483|uniprotkb:Q6VUH9	psi-mi:itm2b_rat(display_long)|uniprotkb:Itm2b(gene name)|psi-mi:Itm2b(display_short)|uniprotkb:Immature BRI2(gene name synonym)|uniprotkb:Transmembrane protein BRI(gene name synonym)	psi-mi:lsamp_rat(display_long)|uniprotkb:Lsamp(gene name)|psi-mi:Lsamp(display_short)|uniprotkb:Lamp(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Martins et al. (2018)	imex:IM-28469|pubmed:29476059	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26438079|imex:IM-28469-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSRNOG00000016271(gene)|ensembl:ENSRNOT00000023037(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001540"(amyloid-beta binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0010008"(endosome membrane)|go:"GO:0030660"(Golgi-associated vesicle membrane)|go:"GO:0031301"(integral component of organelle membrane)|go:"GO:0042985"(negative regulation of amyloid precursor protein biosynthetic process)|interpro:IPR007084(BRICHOS)|interpro:IPR040145|mint:Q5XIE8|refseq:NP_001006964.1|rgd:620727	go:"GO:0005886"(plasma membrane)|go:"GO:0007155"(cell adhesion)|go:"GO:0031225"(anchored component of membrane)|go:"GO:0035641"(locomotory exploration behavior)|reactome:R-RNO-163125|mint:Q62813|refseq:NP_058938.1|refseq:XP_006248401.1|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR036179|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR013098(Immunoglobulin I-set)|interpro:IPR003599(Immunoglobulin subtype)|interpro:IPR003598(Immunoglobulin subtype 2)|rgd:71102	-	-	-	figure legend:ST1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10116(rat-brain-cerebellum)|taxid:10116(Rattus norvegicus)	-	2020/10/30	2020/10/30	rogid:DtE+ZXAZKdCMvUW5K+jXQ5bH07M10116	rogid:6BAFouzZzIUyYWrT4mMyKtsOojY10116	rigid:OaXQ9NA25fwCWxejPU3Ao9q5j/E	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q5XIE8	uniprotkb:P56536	intact:EBI-15348306|ensembl:ENSRNOP00000023037	intact:EBI-994504	psi-mi:itm2b_rat(display_long)|uniprotkb:Itm2b(gene name)|psi-mi:Itm2b(display_short)|uniprotkb:Immature BRI2(gene name synonym)|uniprotkb:Transmembrane protein BRI(gene name synonym)	psi-mi:kif5c_rat(display_long)|uniprotkb:Kinesin heavy chain neuron-specific 2(gene name synonym)|uniprotkb:Kif5c(gene name)|psi-mi:Kif5c(display_short)|uniprotkb:Nkhc2(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Martins et al. (2018)	imex:IM-28469|pubmed:29476059	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26438079|imex:IM-28469-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSRNOG00000016271(gene)|ensembl:ENSRNOT00000023037(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001540"(amyloid-beta binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0010008"(endosome membrane)|go:"GO:0030660"(Golgi-associated vesicle membrane)|go:"GO:0031301"(integral component of organelle membrane)|go:"GO:0042985"(negative regulation of amyloid precursor protein biosynthetic process)|interpro:IPR007084(BRICHOS)|interpro:IPR040145|mint:Q5XIE8|refseq:NP_001006964.1|rgd:620727	go:"GO:0003777"(microtubule motor activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005871"(kinesin complex)|go:"GO:0005874"(microtubule)|go:"GO:0007018"(microtubule-based movement)|go:"GO:0007411"(axon guidance)|go:"GO:0008017"(microtubule binding)|go:"GO:0008045"(motor neuron axon guidance)|go:"GO:0008574"(plus-end-directed microtubule motor activity)|go:"GO:0030425"(dendrite)|go:"GO:0030705"(cytoskeleton-dependent intracellular transport)|go:"GO:0032839"(dendrite cytoplasm)|go:"GO:0034190"(apolipoprotein receptor binding)|go:"GO:0035253"(ciliary rootlet)|go:"GO:0043005"(neuron projection)|go:"GO:0043025"(neuronal cell body)|go:"GO:0044295"(axonal growth cone)|go:"GO:0046034"(ATP metabolic process)|go:"GO:0048489"(synaptic vesicle transport)|go:"GO:0051028"(mRNA transport)|go:"GO:0098963"(dendritic transport of messenger ribonucleoprotein complex)|go:"GO:0098964"(anterograde dendritic transport of messenger ribonucleoprotein complex)|go:"GO:0098971"(anterograde dendritic transport of neurotransmitter receptor complex)|go:"GO:0099641"(anterograde axonal protein transport)|go:"GO:0150034"(distal axon)|go:"GO:1904115"(axon cytoplasm)|rcsb pdb:2KIN|rcsb pdb:3KIN|rgd:1308539|interpro:IPR019821|interpro:IPR001752(Kinesin, motor region)|interpro:IPR027417|mint:P56536|interpro:IPR036961	-	-	-	figure legend:ST1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10116(rat-brain-cerebellum)|taxid:10116(Rattus norvegicus)	-	2020/10/30	2020/10/30	rogid:DtE+ZXAZKdCMvUW5K+jXQ5bH07M10116	rogid:XicHwXiTTxlnHBH1NkJ0SCgSGzY10116	rigid:OaXQ9NA25fwCWxejPU3Ao9q5j/E	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q5XIE8	uniprotkb:Q9ESM2	intact:EBI-15348306|ensembl:ENSRNOP00000023037	intact:EBI-26437461	psi-mi:itm2b_rat(display_long)|uniprotkb:Itm2b(gene name)|psi-mi:Itm2b(display_short)|uniprotkb:Immature BRI2(gene name synonym)|uniprotkb:Transmembrane protein BRI(gene name synonym)	psi-mi:hpln2_rat(display_long)|uniprotkb:Hapln2(gene name)|psi-mi:Hapln2(display_short)|uniprotkb:Bral1(gene name synonym)|uniprotkb:Brain link protein 1(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Martins et al. (2018)	imex:IM-28469|pubmed:29476059	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26438079|imex:IM-28469-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSRNOG00000016271(gene)|ensembl:ENSRNOT00000023037(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001540"(amyloid-beta binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0010008"(endosome membrane)|go:"GO:0030660"(Golgi-associated vesicle membrane)|go:"GO:0031301"(integral component of organelle membrane)|go:"GO:0042985"(negative regulation of amyloid precursor protein biosynthetic process)|interpro:IPR007084(BRICHOS)|interpro:IPR040145|mint:Q5XIE8|refseq:NP_001006964.1|rgd:620727	go:"GO:0001501"(skeletal system development)|go:"GO:0005540"(hyaluronic acid binding)|go:"GO:0005576"(extracellular region)|go:"GO:0007155"(cell adhesion)|go:"GO:0007417"(central nervous system development)|go:"GO:0008065"(establishment of blood-nerve barrier)|go:"GO:0031012"(extracellular matrix)|go:"GO:0085029"(extracellular matrix assembly)|mint:Q9ESM2|refseq:NP_071621.1|interpro:IPR016186(C-type lectin-like)|interpro:IPR016187(C-type lectin fold)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR036179|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR003599(Immunoglobulin subtype)|interpro:IPR003598(Immunoglobulin subtype 2)|interpro:IPR013106(Immunoglobulin V-set)|interpro:IPR000538(Link)|rgd:621854	-	-	-	figure legend:ST1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10116(rat-brain-cerebellum)|taxid:10116(Rattus norvegicus)	-	2020/10/30	2020/10/30	rogid:DtE+ZXAZKdCMvUW5K+jXQ5bH07M10116	rogid:297Sn7Zp2xwT0u36s49tA1bzdUs10116	rigid:OaXQ9NA25fwCWxejPU3Ao9q5j/E	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q5XIE8	uniprotkb:P02262	intact:EBI-15348306|ensembl:ENSRNOP00000023037	intact:EBI-5747219	psi-mi:itm2b_rat(display_long)|uniprotkb:Itm2b(gene name)|psi-mi:Itm2b(display_short)|uniprotkb:Immature BRI2(gene name synonym)|uniprotkb:Transmembrane protein BRI(gene name synonym)	psi-mi:h2a1_rat(display_long)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Martins et al. (2018)	imex:IM-28469|pubmed:29476059	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26438079|imex:IM-28469-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSRNOG00000016271(gene)|ensembl:ENSRNOT00000023037(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001540"(amyloid-beta binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0010008"(endosome membrane)|go:"GO:0030660"(Golgi-associated vesicle membrane)|go:"GO:0031301"(integral component of organelle membrane)|go:"GO:0042985"(negative regulation of amyloid precursor protein biosynthetic process)|interpro:IPR007084(BRICHOS)|interpro:IPR040145|mint:Q5XIE8|refseq:NP_001006964.1|rgd:620727	interpro:IPR009072(Histone-fold)|interpro:IPR007125(Histone core)|interpro:IPR002119(Histone H2A)|mint:P02262|interpro:IPR032454|interpro:IPR032458|go:"GO:0000786"(nucleosome)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0006342"|go:"GO:0046982"(protein heterodimerization activity)	-	-	-	figure legend:ST1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10116(rat-brain-cerebellum)|taxid:10116(Rattus norvegicus)	-	2020/10/30	2020/10/30	rogid:DtE+ZXAZKdCMvUW5K+jXQ5bH07M10116	rogid:yNvHACh66Sn9zW5OVCHxC5BdNKA10116	rigid:OaXQ9NA25fwCWxejPU3Ao9q5j/E	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q5XIE8	uniprotkb:Q794E4	intact:EBI-15348306|ensembl:ENSRNOP00000023037	intact:EBI-919306|ensembl:ENSRNOP00000019529|ensembl:ENSRNOP00000068652|ensembl:ENSRNOP00000069655	psi-mi:itm2b_rat(display_long)|uniprotkb:Itm2b(gene name)|psi-mi:Itm2b(display_short)|uniprotkb:Immature BRI2(gene name synonym)|uniprotkb:Transmembrane protein BRI(gene name synonym)	psi-mi:hnrpf_rat(display_long)|uniprotkb:Hnrnpf(gene name)|psi-mi:Hnrnpf(display_short)|uniprotkb:Hnrpf(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Martins et al. (2018)	imex:IM-28469|pubmed:29476059	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26438079|imex:IM-28469-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSRNOG00000016271(gene)|ensembl:ENSRNOT00000023037(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001540"(amyloid-beta binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0010008"(endosome membrane)|go:"GO:0030660"(Golgi-associated vesicle membrane)|go:"GO:0031301"(integral component of organelle membrane)|go:"GO:0042985"(negative regulation of amyloid precursor protein biosynthetic process)|interpro:IPR007084(BRICHOS)|interpro:IPR040145|mint:Q5XIE8|refseq:NP_001006964.1|rgd:620727	rgd:620366|refseq:NP_001032362.1|refseq:NP_001032363.1|refseq:NP_001032364.1|refseq:NP_071792.1|refseq:XP_008761484.1|refseq:XP_017448358.1|refseq:XP_017448359.1|refseq:XP_017448360.1|refseq:XP_017448361.1|refseq:XP_017448362.1|refseq:XP_017448363.1|refseq:XP_017448364.1|ensembl:ENSRNOG00000014562(gene)|ensembl:ENSRNOT00000019529(transcript)|ensembl:ENSRNOT00000083843(transcript)|ensembl:ENSRNOT00000091765(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0003727"(single-stranded RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006397"(mRNA processing)|go:"GO:0008380"(RNA splicing)|go:"GO:0017025"(TBP-class protein binding)|go:"GO:0043484"(regulation of RNA splicing)|go:"GO:0071013"(catalytic step 2 spliceosome)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR012996(Zinc finger, CHHC-type)|interpro:IPR035979|mint:Q794E4|reactome:R-RNO-6803529|reactome:R-RNO-72163	-	-	-	figure legend:ST1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10116(rat-brain-cerebellum)|taxid:10116(Rattus norvegicus)	-	2020/10/30	2020/10/30	rogid:DtE+ZXAZKdCMvUW5K+jXQ5bH07M10116	rogid:Ntkz1kjm7RteL6dBzMmC0sipvCk10116	rigid:OaXQ9NA25fwCWxejPU3Ao9q5j/E	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q5XIE8	uniprotkb:Q9JJ54	intact:EBI-15348306|ensembl:ENSRNOP00000023037	intact:EBI-2696704|uniprotkb:Q9JJ51|uniprotkb:Q9JJ52|uniprotkb:Q9JJ53|ensembl:ENSRNOP00000046491|uniprotkb:G3V9G2|uniprotkb:P17132	psi-mi:itm2b_rat(display_long)|uniprotkb:Itm2b(gene name)|psi-mi:Itm2b(display_short)|uniprotkb:Immature BRI2(gene name synonym)|uniprotkb:Transmembrane protein BRI(gene name synonym)	psi-mi:hnrpd_rat(display_long)|uniprotkb:Hnrnpd(gene name)|psi-mi:Hnrnpd(display_short)|uniprotkb:Auf1(gene name synonym)|uniprotkb:Hnrpd(gene name synonym)|uniprotkb:AU-rich element RNA-binding protein 1(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Martins et al. (2018)	imex:IM-28469|pubmed:29476059	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26438079|imex:IM-28469-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSRNOG00000016271(gene)|ensembl:ENSRNOT00000023037(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001540"(amyloid-beta binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0010008"(endosome membrane)|go:"GO:0030660"(Golgi-associated vesicle membrane)|go:"GO:0031301"(integral component of organelle membrane)|go:"GO:0042985"(negative regulation of amyloid precursor protein biosynthetic process)|interpro:IPR007084(BRICHOS)|interpro:IPR040145|mint:Q5XIE8|refseq:NP_001006964.1|rgd:620727	rgd:620365|refseq:NP_001076008.1|refseq:NP_001076009.1|refseq:NP_001076010.1|refseq:NP_077380.2|ensembl:ENSRNOG00000002292(gene)|ensembl:ENSRNOT00000047840(transcript)|go:"GO:0001889"(liver development)|go:"GO:0003680"(minor groove of adenine-thymine-rich DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006913"(nucleocytoplasmic transport)|go:"GO:0007420"(brain development)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0000291"(nuclear-transcribed mRNA catabolic process, exonucleolytic)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0021549"(cerebellum development)|go:"GO:0032204"(regulation of telomere maintenance)|go:"GO:0032355"(response to estradiol)|go:"GO:0035925"(mRNA 3'-UTR AU-rich region binding)|go:"GO:0042162"(telomeric DNA binding)|go:"GO:0042752"(regulation of circadian rhythm)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0043488"(regulation of mRNA stability)|go:"GO:0045202"(synapse)|go:"GO:0045727"(positive regulation of translation)|go:"GO:0048255"(mRNA stabilization)|go:"GO:0051592"(response to calcium ion)|go:"GO:0051602"(response to electrical stimulus)|go:"GO:0061158"(3'-UTR-mediated mRNA destabilization)|go:"GO:0071230"(cellular response to amino acid stimulus)|go:"GO:0071392"(cellular response to estradiol stimulus)|go:"GO:0071732"(cellular response to nitric oxide)|go:"GO:0097167"(circadian regulation of translation)|go:"GO:1901355"(response to rapamycin)|go:"GO:1904355"(positive regulation of telomere capping)|go:"GO:1904383"(response to sodium phosphate)|go:"GO:1904586"(cellular response to putrescine)|go:"GO:1905663"(positive regulation of telomerase RNA reverse transcriptase activity)|go:"GO:1990828"(hepatocyte dedifferentiation)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR012956(CBF, N-terminal)|interpro:IPR035979|mint:Q9JJ54|reactome:R-RNO-450408|reactome:R-RNO-72163	-	-	-	figure legend:ST1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10116(rat-brain-cerebellum)|taxid:10116(Rattus norvegicus)	-	2020/10/30	2020/10/30	rogid:DtE+ZXAZKdCMvUW5K+jXQ5bH07M10116	rogid:fV91RKUcQMG97Am2q0D9jmps1Uw10116	rigid:OaXQ9NA25fwCWxejPU3Ao9q5j/E	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q5XIE8	uniprotkb:Q6URK4	intact:EBI-15348306|ensembl:ENSRNOP00000023037	intact:EBI-2696754|uniprotkb:Q6URK3|ensembl:ENSRNOP00000069876	psi-mi:itm2b_rat(display_long)|uniprotkb:Itm2b(gene name)|psi-mi:Itm2b(display_short)|uniprotkb:Immature BRI2(gene name synonym)|uniprotkb:Transmembrane protein BRI(gene name synonym)	psi-mi:roa3_rat(display_long)|uniprotkb:Hnrnpa3(gene name)|psi-mi:Hnrnpa3(display_short)|uniprotkb:Hnrpa3(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Martins et al. (2018)	imex:IM-28469|pubmed:29476059	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26438079|imex:IM-28469-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSRNOG00000016271(gene)|ensembl:ENSRNOT00000023037(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001540"(amyloid-beta binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0010008"(endosome membrane)|go:"GO:0030660"(Golgi-associated vesicle membrane)|go:"GO:0031301"(integral component of organelle membrane)|go:"GO:0042985"(negative regulation of amyloid precursor protein biosynthetic process)|interpro:IPR007084(BRICHOS)|interpro:IPR040145|mint:Q5XIE8|refseq:NP_001006964.1|rgd:620727	rgd:727807|refseq:NP_001104764.1|refseq:NP_001104765.1|refseq:NP_937765.1|refseq:XP_008760133.1|refseq:XP_008760134.1|ensembl:ENSRNOG00000052968(gene)|ensembl:ENSRNOT00000078872(transcript)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006397"(mRNA processing)|go:"GO:0008380"(RNA splicing)|go:"GO:0014069"(postsynaptic density)|go:"GO:0035770"(ribonucleoprotein granule)|go:"GO:0043005"(neuron projection)|go:"GO:0051028"(mRNA transport)|go:"GO:0051033"(RNA transmembrane transporter activity)|go:"GO:0071013"(catalytic step 2 spliceosome)|go:"GO:1990124"(messenger ribonucleoprotein complex)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR034513|interpro:IPR034516|interpro:IPR035979|mint:Q6URK4|reactome:R-RNO-72163	-	-	-	figure legend:ST1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10116(rat-brain-cerebellum)|taxid:10116(Rattus norvegicus)	-	2020/10/30	2020/10/30	rogid:DtE+ZXAZKdCMvUW5K+jXQ5bH07M10116	rogid:KcZjXvHON9QZSqHWi4nWSDz/HtE10116	rigid:OaXQ9NA25fwCWxejPU3Ao9q5j/E	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q5XIE8	uniprotkb:Q68FP1	intact:EBI-15348306|ensembl:ENSRNOP00000023037	intact:EBI-6096401|ensembl:ENSRNOP00000025857	psi-mi:itm2b_rat(display_long)|uniprotkb:Itm2b(gene name)|psi-mi:Itm2b(display_short)|uniprotkb:Immature BRI2(gene name synonym)|uniprotkb:Transmembrane protein BRI(gene name synonym)	psi-mi:gels_rat(display_long)|uniprotkb:Gsn(gene name)|psi-mi:Gsn(display_short)|uniprotkb:Actin-depolymerizing factor(gene name synonym)|uniprotkb:Brevin(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Martins et al. (2018)	imex:IM-28469|pubmed:29476059	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26438079|imex:IM-28469-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSRNOG00000016271(gene)|ensembl:ENSRNOT00000023037(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001540"(amyloid-beta binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0010008"(endosome membrane)|go:"GO:0030660"(Golgi-associated vesicle membrane)|go:"GO:0031301"(integral component of organelle membrane)|go:"GO:0042985"(negative regulation of amyloid precursor protein biosynthetic process)|interpro:IPR007084(BRICHOS)|interpro:IPR040145|mint:Q5XIE8|refseq:NP_001006964.1|rgd:620727	rgd:1303089|refseq:NP_001004080.1|refseq:XP_006234102.1|ensembl:ENSRNOG00000018991(gene)|ensembl:ENSRNOT00000025857(transcript)|go:"GO:0001726"(ruffle)|go:"GO:0002102"(podosome)|go:"GO:0003779"(actin binding)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005546"(phosphatidylinositol-4,5-bisphosphate binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005925"(focal adhesion)|go:"GO:0006911"(phagocytosis, engulfment)|go:"GO:0006915"(apoptotic process)|go:"GO:0007417"(central nervous system development)|go:"GO:0007568"(aging)|go:"GO:0008154"(actin polymerization or depolymerization)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0014003"(oligodendrocyte development)|go:"GO:0014891"(striated muscle atrophy)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0016192"(vesicle-mediated transport)|go:"GO:0016528"(sarcoplasm)|go:"GO:0030027"(lamellipodium)|go:"GO:0030031"(cell projection assembly)|go:"GO:0030036"(actin cytoskeleton organization)|go:"GO:0030041"(actin filament polymerization)|go:"GO:0030042"(actin filament depolymerization)|go:"GO:0030155"(regulation of cell adhesion)|go:"GO:0030478"(actin cap)|go:"GO:0030864"(cortical actin cytoskeleton)|go:"GO:0031648"(protein destabilization)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035994"(response to muscle stretch)|go:"GO:0036313"(phosphatidylinositol 3-kinase catalytic subunit binding)|go:"GO:0042060"(wound healing)|go:"GO:0042246"(tissue regeneration)|go:"GO:0042989"(sequestering of actin monomers)|go:"GO:0043209"(myelin sheath)|go:"GO:0045010"(actin nucleation)|go:"GO:0045159"(myosin II binding)|go:"GO:0045335"(phagocytic vesicle)|go:"GO:0046597"(negative regulation of viral entry into host cell)|go:"GO:0048015"(phosphatidylinositol-mediated signaling)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051014"(actin filament severing)|go:"GO:0051015"(actin filament binding)|go:"GO:0051016"(barbed-end actin filament capping)|go:"GO:0051127"(positive regulation of actin nucleation)|go:"GO:0051593"(response to folic acid)|go:"GO:0051693"(actin filament capping)|go:"GO:0055119"(relaxation of cardiac muscle)|go:"GO:0060271"(cilium assembly)|go:"GO:0071276"(cellular response to cadmium ion)|go:"GO:0071346"(cellular response to interferon-gamma)|go:"GO:0071801"(regulation of podosome assembly)|go:"GO:0086003"(cardiac muscle cell contraction)|go:"GO:0090527"(actin filament reorganization)|go:"GO:0097017"(renal protein absorption)|go:"GO:0097284"(hepatocyte apoptotic process)|go:"GO:1902174"(positive regulation of keratinocyte apoptotic process)|go:"GO:1903903"(regulation of establishment of T cell polarity)|go:"GO:1903906"(regulation of plasma membrane raft polarization)|go:"GO:1903909"(regulation of receptor clustering)|go:"GO:1903923"(positive regulation of protein processing in phagocytic vesicle)|go:"GO:1990000"(amyloid fibril formation)|go:"GO:2001269"(positive regulation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway)|interpro:IPR007122(Gelsolin)|interpro:IPR007123(Gelsolin region)|interpro:IPR029006|interpro:IPR030004|mint:Q68FP1|reactome:R-RNO-264870|reactome:R-RNO-6798695|go:"GO:0045471"(response to ethanol)	-	-	-	figure legend:ST1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10116(rat-brain-cerebellum)|taxid:10116(Rattus norvegicus)	-	2020/10/30	2020/10/30	rogid:DtE+ZXAZKdCMvUW5K+jXQ5bH07M10116	rogid:VEJohA79kwmQ8WB+zZ5DO5Wjw1g10116	rigid:OaXQ9NA25fwCWxejPU3Ao9q5j/E	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q5XIE8	uniprotkb:Q62696	intact:EBI-15348306|ensembl:ENSRNOP00000023037	intact:EBI-389325	psi-mi:itm2b_rat(display_long)|uniprotkb:Itm2b(gene name)|psi-mi:Itm2b(display_short)|uniprotkb:Immature BRI2(gene name synonym)|uniprotkb:Transmembrane protein BRI(gene name synonym)	psi-mi:dlg1_rat(display_long)|uniprotkb:Dlg1(gene name)|psi-mi:Dlg1(display_short)|uniprotkb:Synapse-associated protein 97(gene name synonym)|uniprotkb:Dlgh1(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Martins et al. (2018)	imex:IM-28469|pubmed:29476059	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26438079|imex:IM-28469-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSRNOG00000016271(gene)|ensembl:ENSRNOT00000023037(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001540"(amyloid-beta binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0010008"(endosome membrane)|go:"GO:0030660"(Golgi-associated vesicle membrane)|go:"GO:0031301"(integral component of organelle membrane)|go:"GO:0042985"(negative regulation of amyloid precursor protein biosynthetic process)|interpro:IPR007084(BRICHOS)|interpro:IPR040145|mint:Q5XIE8|refseq:NP_001006964.1|rgd:620727	rgd:2505|refseq:NP_036920.1|go:"GO:0043219"(lateral loop)|go:"GO:0043268"(positive regulation of potassium ion transport)|go:"GO:0043622"(cortical microtubule organization)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0045121"(membrane raft)|go:"GO:0045197"(establishment or maintenance of epithelial cell apical/basal polarity)|go:"GO:0045202"(synapse)|go:"GO:0045211"(postsynaptic membrane)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0048608"(reproductive structure development)|go:"GO:0048704"(embryonic skeletal system morphogenesis)|go:"GO:0048729"(tissue morphogenesis)|go:"GO:0048745"(smooth muscle tissue development)|go:"GO:0050680"(negative regulation of epithelial cell proliferation)|go:"GO:0051660"(establishment of centrosome localization)|go:"GO:0051898"(negative regulation of protein kinase B signaling)|go:"GO:0060022"(hard palate development)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0070373"(negative regulation of ERK1 and ERK2 cascade)|go:"GO:0070830"(bicellular tight junction assembly)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0097016"(L27 domain binding)|go:"GO:0097025"(MPP7-DLG1-LIN7 complex)|go:"GO:0097060"(synaptic membrane)|go:"GO:0097120"(receptor localization to synapse)|go:"GO:0098609"(cell-cell adhesion)|go:"GO:0098839"(postsynaptic density membrane)|go:"GO:0098911"(regulation of ventricular cardiac muscle cell action potential)|go:"GO:0098919"(structural constituent of postsynaptic density)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099092"(postsynaptic density, intracellular component)|go:"GO:0099645"(neurotransmitter receptor localization to postsynaptic specialization membrane)|go:"GO:1902473"(regulation of protein localization to synapse)|go:"GO:1903078"(positive regulation of protein localization to plasma membrane)|go:"GO:1903286"(regulation of potassium ion import)|go:"GO:1903753"(negative regulation of p38MAPK cascade)|go:"GO:1903760"(regulation of voltage-gated potassium channel activity involved in ventricular cardiac muscle cell action potential repolarization)|go:"GO:1903764"(regulation of potassium ion export across plasma membrane)|go:"GO:2000134"(negative regulation of G1/S transition of mitotic cell cycle)|interpro:IPR001452(Src homology-3)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR004172(L27)|interpro:IPR008144(Guanylate kinase)|interpro:IPR008145(Guanylate kinase/L-type calcium channel region)|interpro:IPR015143(L27-1)|interpro:IPR016313("Membrane-associated guanylate kinase (MAGUK) scaffold protein")|interpro:IPR019583|interpro:IPR019590|interpro:IPR020590|interpro:IPR027417|interpro:IPR036028|interpro:IPR036034|interpro:IPR036892|rcsb pdb:1RSO|rcsb pdb:1ZOK|rcsb pdb:2AWU|rcsb pdb:2AWW|rcsb pdb:2AWX|rcsb pdb:2G2L|rcsb pdb:2I0I|rcsb pdb:2I0L|rcsb pdb:3UAT|reactome:R-RNO-399719|reactome:R-RNO-438066|reactome:R-RNO-451308|reactome:R-RNO-5673001|reactome:R-RNO-8849932|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0005874"(microtubule)|go:"GO:0005886"(plasma membrane)|go:"GO:0005902"(microvillus)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005923"(bicellular tight junction)|go:"GO:0007015"(actin filament organization)|go:"GO:0007155"(cell adhesion)|go:"GO:0007268"(chemical synaptic transmission)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008104"(protein localization)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0008360"(regulation of cell shape)|go:"GO:0009898"(cytoplasmic side of plasma membrane)|go:"GO:0009925"(basal plasma membrane)|go:"GO:0014069"(postsynaptic density)|go:"GO:0015459"(potassium channel regulator activity)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0016328"(lateral plasma membrane)|go:"GO:0019894"(kinesin binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0019902"(phosphatase binding)|go:"GO:0030054"(cell junction)|go:"GO:0030165"(PDZ domain binding)|go:"GO:0030315"(T-tubule)|go:"GO:0030425"(dendrite)|go:"GO:0030432"(peristalsis)|go:"GO:0030672"(synaptic vesicle membrane)|go:"GO:0030838"(positive regulation of actin filament polymerization)|go:"GO:0030866"(cortical actin cytoskeleton organization)|go:"GO:0030953"(astral microtubule organization)|go:"GO:0031253"(cell projection membrane)|go:"GO:0031434"(mitogen-activated protein kinase kinase binding)|go:"GO:0031579"(membrane raft organization)|go:"GO:0031594"(neuromuscular junction)|go:"GO:0031641"(regulation of myelination)|go:"GO:0032147"(activation of protein kinase activity)|go:"GO:0032880"(regulation of protein localization)|go:"GO:0033268"(node of Ranvier)|go:"GO:0033270"(paranode region of axon)|go:"GO:0034629"|go:"GO:0035255"(ionotropic glutamate receptor binding)|go:"GO:0035748"(myelin sheath abaxonal region)|go:"GO:0042110"(T cell activation)|go:"GO:0042130"(negative regulation of T cell proliferation)|go:"GO:0042391"(regulation of membrane potential)|go:"GO:0042734"(presynaptic membrane)|go:"GO:0042982"(amyloid precursor protein metabolic process)|go:"GO:0043005"(neuron projection)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043113"(receptor clustering)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0001657"(ureteric bud development)|go:"GO:0001658"(branching involved in ureteric bud morphogenesis)|go:"GO:0001771"(immunological synapse formation)|go:"GO:0001772"(immunological synapse)|go:"GO:0001935"(endothelial cell proliferation)|go:"GO:0002088"(lens development in camera-type eye)|go:"GO:0005604"(basement membrane)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|mint:Q62696|dip:DIP-31527N	-	-	-	figure legend:ST1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10116(rat-brain-cerebellum)|taxid:10116(Rattus norvegicus)	-	2020/10/30	2020/10/30	rogid:DtE+ZXAZKdCMvUW5K+jXQ5bH07M10116	rogid:ThHAJAsBhWNjz4P6frniUm2xaJI10116	rigid:OaXQ9NA25fwCWxejPU3Ao9q5j/E	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q5XIE8	uniprotkb:O08651	intact:EBI-15348306|ensembl:ENSRNOP00000023037	intact:EBI-915450|uniprotkb:Q546Q9|ensembl:ENSRNOP00000053019	psi-mi:itm2b_rat(display_long)|uniprotkb:Itm2b(gene name)|psi-mi:Itm2b(display_short)|uniprotkb:Immature BRI2(gene name synonym)|uniprotkb:Transmembrane protein BRI(gene name synonym)	psi-mi:sera_rat(display_long)|uniprotkb:Phgdh(gene name)|psi-mi:Phgdh(display_short)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Martins et al. (2018)	imex:IM-28469|pubmed:29476059	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26438079|imex:IM-28469-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSRNOG00000016271(gene)|ensembl:ENSRNOT00000023037(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001540"(amyloid-beta binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0010008"(endosome membrane)|go:"GO:0030660"(Golgi-associated vesicle membrane)|go:"GO:0031301"(integral component of organelle membrane)|go:"GO:0042985"(negative regulation of amyloid precursor protein biosynthetic process)|interpro:IPR007084(BRICHOS)|interpro:IPR040145|mint:Q5XIE8|refseq:NP_001006964.1|rgd:620727	rgd:61987|refseq:NP_113808.1|refseq:XP_006233072.1|ensembl:ENSRNOG00000019328(gene)|ensembl:ENSRNOT00000056173(transcript)|go:"GO:0004617"(phosphoglycerate dehydrogenase activity)|go:"GO:0006541"(glutamine metabolic process)|go:"GO:0006544"(glycine metabolic process)|go:"GO:0006563"(L-serine metabolic process)|go:"GO:0006564"(L-serine biosynthetic process)|go:"GO:0006566"(threonine metabolic process)|go:"GO:0009070"(serine family amino acid biosynthetic process)|go:"GO:0009448"(gamma-aminobutyric acid metabolic process)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0019530"(taurine metabolic process)|go:"GO:0021510"(spinal cord development)|go:"GO:0021782"(glial cell development)|go:"GO:0021915"(neural tube development)|go:"GO:0022008"(neurogenesis)|go:"GO:0031175"(neuron projection development)|go:"GO:0051287"(NAD binding)|go:"GO:0070314"(G1 to G0 transition)|interpro:IPR006139(D-isomer specific 2-hydroxyacid dehydrogenase, catalytic region)|interpro:IPR006140(D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding)|interpro:IPR006236(D-3-phosphoglycerate dehydrogenase)|interpro:IPR029009|interpro:IPR029752|interpro:IPR029753|interpro:IPR036291|mint:O08651|reactome:R-RNO-977347	-	-	-	figure legend:ST1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10116(rat-brain-cerebellum)|taxid:10116(Rattus norvegicus)	-	2020/10/30	2020/10/30	rogid:DtE+ZXAZKdCMvUW5K+jXQ5bH07M10116	rogid:HxRSndxyMrzoSms31Sg/CpNk5eU10116	rigid:OaXQ9NA25fwCWxejPU3Ao9q5j/E	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q5XIE8	uniprotkb:P97846	intact:EBI-15348306|ensembl:ENSRNOP00000023037	intact:EBI-26437421|ensembl:ENSRNOP00000027505	psi-mi:itm2b_rat(display_long)|uniprotkb:Itm2b(gene name)|psi-mi:Itm2b(display_short)|uniprotkb:Immature BRI2(gene name synonym)|uniprotkb:Transmembrane protein BRI(gene name synonym)	psi-mi:cntp1_rat(display_long)|uniprotkb:Cntnap1(gene name)|psi-mi:Cntnap1(display_short)|uniprotkb:Caspr(gene name synonym)|uniprotkb:Nrxn4(gene name synonym)|uniprotkb:Neurexin IV(gene name synonym)|uniprotkb:Neurexin-4(gene name synonym)|uniprotkb:Paranodin(gene name synonym)|uniprotkb:p190(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Martins et al. (2018)	imex:IM-28469|pubmed:29476059	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26438079|imex:IM-28469-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSRNOG00000016271(gene)|ensembl:ENSRNOT00000023037(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001540"(amyloid-beta binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0010008"(endosome membrane)|go:"GO:0030660"(Golgi-associated vesicle membrane)|go:"GO:0031301"(integral component of organelle membrane)|go:"GO:0042985"(negative regulation of amyloid precursor protein biosynthetic process)|interpro:IPR007084(BRICHOS)|interpro:IPR040145|mint:Q5XIE8|refseq:NP_001006964.1|rgd:620727	ensembl:ENSRNOG00000020277(gene)|ensembl:ENSRNOT00000027505(transcript)|go:"GO:0002175"(protein localization to paranode region of axon)|go:"GO:0005918"(septate junction)|go:"GO:0007010"(cytoskeleton organization)|go:"GO:0007155"(cell adhesion)|go:"GO:0016021"(integral component of membrane)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0019227"(neuronal action potential propagation)|go:"GO:0022010"(central nervous system myelination)|go:"GO:0022011"(myelination in peripheral nervous system)|go:"GO:0030424"(axon)|go:"GO:0030913"(paranodal junction assembly)|go:"GO:0031175"(neuron projection development)|go:"GO:0033010"(paranodal junction)|go:"GO:0033270"(paranode region of axon)|go:"GO:0042552"(myelination)|go:"GO:0048787"(presynaptic active zone membrane)|go:"GO:0048812"(neuron projection morphogenesis)|go:"GO:0050884"(neuromuscular process controlling posture)|go:"GO:0050885"(neuromuscular process controlling balance)|go:"GO:0071205"(protein localization to juxtaparanode region of axon)|interpro:IPR000421(Coagulation factor 5/8 type, C-terminal)|interpro:IPR000742(EGF-like, type 3)|interpro:IPR001791(Laminin G)|interpro:IPR002181(Fibrinogen, alpha/beta/gamma chain, C-terminal globular)|interpro:IPR003585(Neurexin/syndecan/glycophorin C)|interpro:IPR008979(Galactose-binding like)|interpro:IPR013320(Concanavalin A-like lectin/glucanase, subgroup)|interpro:IPR028872|interpro:IPR036056|mint:P97846|refseq:NP_114450.1|rgd:70902	-	-	-	figure legend:ST1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10116(rat-brain-cerebellum)|taxid:10116(Rattus norvegicus)	-	2020/10/30	2020/10/30	rogid:DtE+ZXAZKdCMvUW5K+jXQ5bH07M10116	rogid:oJ+zmI5E4kZhbUEl3xmU8iqt8v410116	rigid:OaXQ9NA25fwCWxejPU3Ao9q5j/E	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q5XIE8	uniprotkb:Q9WU82	intact:EBI-15348306|ensembl:ENSRNOP00000023037	intact:EBI-920177	psi-mi:itm2b_rat(display_long)|uniprotkb:Itm2b(gene name)|psi-mi:Itm2b(display_short)|uniprotkb:Immature BRI2(gene name synonym)|uniprotkb:Transmembrane protein BRI(gene name synonym)	psi-mi:ctnb1_rat(display_long)|uniprotkb:Ctnnb1(gene name)|psi-mi:Ctnnb1(display_short)|uniprotkb:Catnb(gene name synonym)|uniprotkb:Beta-catenin(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Martins et al. (2018)	imex:IM-28469|pubmed:29476059	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26438079|imex:IM-28469-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSRNOG00000016271(gene)|ensembl:ENSRNOT00000023037(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001540"(amyloid-beta binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0010008"(endosome membrane)|go:"GO:0030660"(Golgi-associated vesicle membrane)|go:"GO:0031301"(integral component of organelle membrane)|go:"GO:0042985"(negative regulation of amyloid precursor protein biosynthetic process)|interpro:IPR007084(BRICHOS)|interpro:IPR040145|mint:Q5XIE8|refseq:NP_001006964.1|rgd:620727	rgd:70487|refseq:NP_445809.2|refseq:XP_008764913.1|refseq:XP_017451425.1|refseq:XP_017451426.1|refseq:XP_017451428.1|refseq:XP_017451429.1|mint:Q9WU82|dip:DIP-37053N|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0000578"(embryonic axis specification)|go:"GO:0000791"(euchromatin)|go:"GO:0000904"(cell morphogenesis involved in differentiation)|go:"GO:0000922"(spindle pole)|go:"GO:0001221"(transcription coregulator binding)|go:"GO:0001501"(skeletal system development)|go:"GO:0001569"(branching involved in blood vessel morphogenesis)|go:"GO:0001570"(vasculogenesis)|go:"GO:0001658"(branching involved in ureteric bud morphogenesis)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0001702"(gastrulation with mouth forming second)|go:"GO:0001706"(endoderm formation)|go:"GO:0001708"(cell fate specification)|go:"GO:0001709"(cell fate determination)|go:"GO:0001711"(endodermal cell fate commitment)|go:"GO:0001764"(neuron migration)|go:"GO:0001822"(kidney development)|go:"GO:0001840"(neural plate development)|go:"GO:0001889"(liver development)|go:"GO:0001894"(tissue homeostasis)|go:"GO:0001944"(vasculature development)|go:"GO:0002052"(positive regulation of neuroblast proliferation)|go:"GO:0002053"(positive regulation of mesenchymal cell proliferation)|go:"GO:0002089"(lens morphogenesis in camera-type eye)|go:"GO:0003266"(regulation of secondary heart field cardioblast proliferation)|go:"GO:0003338"(metanephros morphogenesis)|go:"GO:0003340"(negative regulation of mesenchymal to epithelial transition involved in metanephros morphogenesis)|go:"GO:0003682"(chromatin binding)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005912"(adherens junction)|go:"GO:0005916"(fascia adherens)|go:"GO:0005923"(bicellular tight junction)|go:"GO:0005938"(cell cortex)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007155"(cell adhesion)|go:"GO:0007160"(cell-matrix adhesion)|go:"GO:0007268"(chemical synaptic transmission)|go:"GO:0007398"(ectoderm development)|go:"GO:0007403"(glial cell fate determination)|go:"GO:0007494"(midgut development)|go:"GO:0007507"(heart development)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008283"(cell population proliferation)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0009725"(response to hormone)|go:"GO:0009948"(anterior/posterior axis specification)|go:"GO:0009950"(dorsal/ventral axis specification)|go:"GO:0009953"(dorsal/ventral pattern formation)|go:"GO:0009954"(proximal/distal pattern formation)|go:"GO:0009987"(cellular process)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0010718"(positive regulation of epithelial to mesenchymal transition)|go:"GO:0010909"(positive regulation of heparan sulfate proteoglycan biosynthetic process)|go:"GO:0014010"(Schwann cell proliferation)|go:"GO:0014070"(response to organic cyclic compound)|go:"GO:0014704"(intercalated disc)|go:"GO:0014823"(response to activity)|go:"GO:0016020"(membrane)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016327"(apicolateral plasma membrane)|go:"GO:0016328"(lateral plasma membrane)|go:"GO:0016331"(morphogenesis of embryonic epithelium)|go:"GO:0016342"(catenin complex)|go:"GO:0016525"(negative regulation of angiogenesis)|go:"GO:0016600"(flotillin complex)|go:"GO:0016922"(nuclear receptor binding)|go:"GO:0019899"(enzyme binding)|go:"GO:0019900"(kinase binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0019903"(protein phosphatase binding)|go:"GO:0021819"(layer formation in cerebral cortex)|go:"GO:0022009"(central nervous system vasculogenesis)|go:"GO:0022405"(hair cycle process)|go:"GO:0030018"(Z disc)|go:"GO:0030027"(lamellipodium)|go:"GO:0030054"(cell junction)|go:"GO:0030097"(hemopoiesis)|go:"GO:0030154"(cell differentiation)|go:"GO:0030182"(neuron differentiation)|go:"GO:0030217"(T cell differentiation)|go:"GO:0030316"(osteoclast differentiation)|go:"GO:0030324"(lung development)|go:"GO:0030331"(estrogen receptor binding)|go:"GO:0030539"(male genitalia development)|go:"GO:0030856"(regulation of epithelial cell differentiation)|go:"GO:0030858"(positive regulation of epithelial cell differentiation)|go:"GO:0030877"(beta-catenin destruction complex)|go:"GO:0030900"(forebrain development)|go:"GO:0030901"(midbrain development)|go:"GO:0030902"(hindbrain development)|go:"GO:0030997"(regulation of centriole-centriole cohesion)|go:"GO:0031016"(pancreas development)|go:"GO:0031069"(hair follicle morphogenesis)|go:"GO:0031253"(cell projection membrane)|go:"GO:0031528"(microvillus membrane)|go:"GO:0031641"(regulation of myelination)|go:"GO:0031965"(nuclear membrane)|go:"GO:0032212"(positive regulation of telomere maintenance via telomerase)|go:"GO:0032331"(negative regulation of chondrocyte differentiation)|go:"GO:0032355"(response to estradiol)|go:"GO:0032968"(positive regulation of transcription elongation from RNA polymerase II promoter)|go:"GO:0032991"(protein-containing complex)|go:"GO:0032993"(protein-DNA complex)|go:"GO:0033077"(T cell differentiation in thymus)|go:"GO:0033234"(negative regulation of protein sumoylation)|go:"GO:0034097"(response to cytokine)|go:"GO:0034332"(adherens junction organization)|go:"GO:0034333"(adherens junction assembly)|go:"GO:0034394"(protein localization to cell surface)|go:"GO:0034613"(cellular protein localization)|go:"GO:0034750"(Scrib-APC-beta-catenin complex)|go:"GO:0035050"(embryonic heart tube development)|go:"GO:0035112"(genitalia morphogenesis)|go:"GO:0035115"(embryonic forelimb morphogenesis)|go:"GO:0035116"(embryonic hindlimb morphogenesis)|go:"GO:0035255"(ionotropic glutamate receptor binding)|go:"GO:0036023"(embryonic skeletal limb joint morphogenesis)|go:"GO:0036520"(astrocyte-dopaminergic neuron signaling)|go:"GO:0042127"(regulation of cell population proliferation)|go:"GO:0042129"(regulation of T cell proliferation)|go:"GO:0042475"(odontogenesis of dentin-containing tooth)|go:"GO:0042493"|go:"GO:0042733"(embryonic digit morphogenesis)|go:"GO:0042734"(presynaptic membrane)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0043198"(dendritic shaft)|go:"GO:0043296"(apical junction complex)|go:"GO:0043410"(positive regulation of MAPK cascade)|go:"GO:0043525"(positive regulation of neuron apoptotic process)|go:"GO:0043588"(skin development)|go:"GO:0043627"(response to estrogen)|go:"GO:0044093"(positive regulation of molecular function)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0044334"(canonical Wnt signaling pathway involved in positive regulation of epithelial to mesenchymal transition)|go:"GO:0044338"(canonical Wnt signaling pathway involved in mesenchymal stem cell differentiation)|go:"GO:0044344"(cellular response to fibroblast growth factor stimulus)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045177"(apical part of cell)|go:"GO:0045202"(synapse)|go:"GO:0045211"(postsynaptic membrane)|go:"GO:0045294"(alpha-catenin binding)|go:"GO:0045296"(cadherin binding)|go:"GO:0045445"(myoblast differentiation)|go:"GO:0045453"(bone resorption)|go:"GO:0045595"(regulation of cell differentiation)|go:"GO:0045596"(negative regulation of cell differentiation)|go:"GO:0045603"(positive regulation of endothelial cell differentiation)|go:"GO:0045667"(regulation of osteoblast differentiation)|go:"GO:0045669"(positive regulation of osteoblast differentiation)|go:"GO:0045670"(regulation of osteoclast differentiation)|go:"GO:0045671"(negative regulation of osteoclast differentiation)|go:"GO:0045743"(positive regulation of fibroblast growth factor receptor signaling pathway)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0045976"(negative regulation of mitotic cell cycle, embryonic)|go:"GO:0046332"(SMAD binding)|go:"GO:0046686"(response to cadmium ion)|go:"GO:0046849"(bone remodeling)|go:"GO:0048469"(cell maturation)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0048489"(synaptic vesicle transport)|go:"GO:0048513"(animal organ development)|go:"GO:0048538"(thymus development)|go:"GO:0048568"(embryonic organ development)|go:"GO:0048599"(oocyte development)|go:"GO:0048617"(embryonic foregut morphogenesis)|go:"GO:0048643"(positive regulation of skeletal muscle tissue development)|go:"GO:0048660"(regulation of smooth muscle cell proliferation)|go:"GO:0048715"(negative regulation of oligodendrocyte differentiation)|go:"GO:0050768"(negative regulation of neurogenesis)|go:"GO:0050808"(synapse organization)|go:"GO:0050998"(nitric-oxide synthase binding)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0051145"(smooth muscle cell differentiation)|go:"GO:0051571"(positive regulation of histone H3-K4 methylation)|go:"GO:0051884"(regulation of timing of anagen)|go:"GO:0051973"(positive regulation of telomerase activity)|go:"GO:0060066"(oviduct development)|go:"GO:0060070"(canonical Wnt signaling pathway)|go:"GO:0060173"(limb development)|go:"GO:0060439"(trachea morphogenesis)|go:"GO:0060440"(trachea formation)|go:"GO:0060441"(epithelial tube branching involved in lung morphogenesis)|go:"GO:0060479"(lung cell differentiation)|go:"GO:0060484"(lung-associated mesenchyme development)|go:"GO:0060492"(lung induction)|go:"GO:0060742"(epithelial cell differentiation involved in prostate gland development)|go:"GO:0060769"(positive regulation of epithelial cell proliferation involved in prostate gland development)|go:"GO:0060789"(hair follicle placode formation)|go:"GO:0060916"(mesenchymal cell proliferation involved in lung development)|go:"GO:0061047"(positive regulation of branching involved in lung morphogenesis)|go:"GO:0061154"(endothelial tube morphogenesis)|go:"GO:0061198"(fungiform papilla formation)|go:"GO:0061324"(canonical Wnt signaling pathway involved in positive regulation of cardiac outflow tract cell proliferation)|go:"GO:0061549"(sympathetic ganglion development)|go:"GO:0061550"(cranial ganglion development)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:0070369"(beta-catenin-TCF7L2 complex)|go:"GO:0070411"(I-SMAD binding)|go:"GO:0070602"(regulation of centromeric sister chromatid cohesion)|go:"GO:0071260"(cellular response to mechanical stimulus)|go:"GO:0071285"(cellular response to lithium ion)|go:"GO:0071363"(cellular response to growth factor stimulus)|go:"GO:0071681"(cellular response to indole-3-methanol)|go:"GO:0071944"(cell periphery)|go:"GO:0072033"(renal vesicle formation)|go:"GO:0072053"(renal inner medulla development)|go:"GO:0072054"(renal outer medulla development)|go:"GO:0072079"(nephron tubule formation)|go:"GO:0072182"(regulation of nephron tubule epithelial cell differentiation)|go:"GO:0090279"(regulation of calcium ion import)|go:"GO:0097091"(synaptic vesicle clustering)|go:"GO:0097718"(disordered domain specific binding)|go:"GO:0098609"(cell-cell adhesion)|go:"GO:0098685"(Schaffer collateral - CA1 synapse)|go:"GO:0098831"(presynaptic active zone cytoplasmic component)|go:"GO:0099092"(postsynaptic density, intracellular component)|go:"GO:0140297"(DNA-binding transcription factor binding)|go:"GO:1901215"(negative regulation of neuron death)|go:"GO:1903204"(negative regulation of oxidative stress-induced neuron death)|go:"GO:1904796"(regulation of core promoter binding)|go:"GO:1904798"(positive regulation of core promoter binding)|go:"GO:1904888"(cranial skeletal system development)|go:"GO:1904948"(midbrain dopaminergic neuron differentiation)|go:"GO:1990138"(neuron projection extension)|go:"GO:1990226"(histone methyltransferase binding)|go:"GO:1990314"(cellular response to insulin-like growth factor stimulus)|go:"GO:1990403"(embryonic brain development)|go:"GO:1990791"(dorsal root ganglion development)|go:"GO:1990907"(beta-catenin-TCF complex)|go:"GO:1990909"(Wnt signalosome)|go:"GO:2000008"(regulation of protein localization to cell surface)|go:"GO:2000017"(positive regulation of determination of dorsal identity)|go:"GO:2000179"(positive regulation of neural precursor cell proliferation)|go:"GO:2001234"(negative regulation of apoptotic signaling pathway)|interpro:IPR000225(Armadillo)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR013284(Beta-catenin)|interpro:IPR016024(Armadillo-type fold)|reactome:R-RNO-195253|reactome:R-RNO-196299|reactome:R-RNO-201681|reactome:R-RNO-201722|reactome:R-RNO-3134973|reactome:R-RNO-351906|reactome:R-RNO-3769402|reactome:R-RNO-4086398|reactome:R-RNO-418990|reactome:R-RNO-4641262|reactome:R-RNO-5218920|reactome:R-RNO-525793|reactome:R-RNO-5626467|reactome:R-RNO-8951430	-	-	-	figure legend:ST1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10116(rat-brain-cerebellum)|taxid:10116(Rattus norvegicus)	-	2020/10/30	2020/10/30	rogid:DtE+ZXAZKdCMvUW5K+jXQ5bH07M10116	rogid:EQ9j/nvYumuF5gT++5hCWaL8cyw10116	rigid:OaXQ9NA25fwCWxejPU3Ao9q5j/E	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q5XIE8	uniprotkb:Q6KC51	intact:EBI-15348306|ensembl:ENSRNOP00000023037	intact:EBI-26437401|uniprotkb:Q6KC50	psi-mi:itm2b_rat(display_long)|uniprotkb:Itm2b(gene name)|psi-mi:Itm2b(display_short)|uniprotkb:Immature BRI2(gene name synonym)|uniprotkb:Transmembrane protein BRI(gene name synonym)	psi-mi:ablm2_rat(display_long)|uniprotkb:Ablim2(gene name)|psi-mi:Ablim2(display_short)|uniprotkb:Actin-binding LIM protein family member 2(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Martins et al. (2018)	imex:IM-28469|pubmed:29476059	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26438079|imex:IM-28469-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSRNOG00000016271(gene)|ensembl:ENSRNOT00000023037(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001540"(amyloid-beta binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0010008"(endosome membrane)|go:"GO:0030660"(Golgi-associated vesicle membrane)|go:"GO:0031301"(integral component of organelle membrane)|go:"GO:0042985"(negative regulation of amyloid precursor protein biosynthetic process)|interpro:IPR007084(BRICHOS)|interpro:IPR040145|mint:Q5XIE8|refseq:NP_001006964.1|rgd:620727	go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0030016"(myofibril)|go:"GO:0030032"(lamellipodium assembly)|go:"GO:0030036"(actin cytoskeleton organization)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|go:"GO:0051015"(actin filament binding)|mint:Q6KC51|refseq:NP_001001514.1|refseq:NP_001171166.1|interpro:IPR028450|interpro:IPR032402|interpro:IPR003128(Villin headpiece)|interpro:IPR036886|interpro:IPR001781(Zinc finger, LIM-type)|rgd:1303094	-	-	-	figure legend:ST1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10116(rat-brain-cerebellum)|taxid:10116(Rattus norvegicus)	-	2020/10/30	2020/10/30	rogid:DtE+ZXAZKdCMvUW5K+jXQ5bH07M10116	rogid:u7CD/CcAAKw3JVQkaKebuX8zOss10116	rigid:OaXQ9NA25fwCWxejPU3Ao9q5j/E	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q5XIE8	uniprotkb:P49911	intact:EBI-15348306|ensembl:ENSRNOP00000023037	intact:EBI-1638376	psi-mi:itm2b_rat(display_long)|uniprotkb:Itm2b(gene name)|psi-mi:Itm2b(display_short)|uniprotkb:Immature BRI2(gene name synonym)|uniprotkb:Transmembrane protein BRI(gene name synonym)	psi-mi:an32a_rat(display_long)|uniprotkb:Anp32a(gene name)|psi-mi:Anp32a(display_short)|uniprotkb:Lanp(gene name synonym)|uniprotkb:Leucine-rich acidic nuclear protein(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Martins et al. (2018)	imex:IM-28469|pubmed:29476059	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26438079|imex:IM-28469-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSRNOG00000016271(gene)|ensembl:ENSRNOT00000023037(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001540"(amyloid-beta binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0010008"(endosome membrane)|go:"GO:0030660"(Golgi-associated vesicle membrane)|go:"GO:0031301"(integral component of organelle membrane)|go:"GO:0042985"(negative regulation of amyloid precursor protein biosynthetic process)|interpro:IPR007084(BRICHOS)|interpro:IPR040145|mint:Q5XIE8|refseq:NP_001006964.1|rgd:620727	mint:P49911|refseq:NP_037035.1|interpro:IPR001611(Leucine-rich repeat)|rgd:11508551|interpro:IPR032675|go:"GO:0005178"(integrin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005829"(cytosol)|go:"GO:0006913"(nucleocytoplasmic transport)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0010977"(negative regulation of neuron projection development)|go:"GO:0016363"(nuclear matrix)|go:"GO:0035067"(negative regulation of histone acetylation)|go:"GO:0042393"(histone binding)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0050839"(cell adhesion molecule binding)|reactome:R-RNO-450520	-	-	-	figure legend:ST1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10116(rat-brain-cerebellum)|taxid:10116(Rattus norvegicus)	-	2020/10/30	2020/10/30	rogid:DtE+ZXAZKdCMvUW5K+jXQ5bH07M10116	rogid:GifxAZWLIiSOf3Wau754tOYzrDY10116	rigid:OaXQ9NA25fwCWxejPU3Ao9q5j/E	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q5XIE8	uniprotkb:P05426	intact:EBI-15348306|ensembl:ENSRNOP00000023037	intact:EBI-779677	psi-mi:itm2b_rat(display_long)|uniprotkb:Itm2b(gene name)|psi-mi:Itm2b(display_short)|uniprotkb:Immature BRI2(gene name synonym)|uniprotkb:Transmembrane protein BRI(gene name synonym)	psi-mi:rl7_rat(display_long)|uniprotkb:Rpl7(gene name)|psi-mi:Rpl7(display_short)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Martins et al. (2018)	imex:IM-28469|pubmed:29476059	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26438079|imex:IM-28469-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSRNOG00000016271(gene)|ensembl:ENSRNOT00000023037(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001540"(amyloid-beta binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0010008"(endosome membrane)|go:"GO:0030660"(Golgi-associated vesicle membrane)|go:"GO:0031301"(integral component of organelle membrane)|go:"GO:0042985"(negative regulation of amyloid precursor protein biosynthetic process)|interpro:IPR007084(BRICHOS)|interpro:IPR040145|mint:Q5XIE8|refseq:NP_001006964.1|rgd:620727	rgd:735169|interpro:IPR018038|interpro:IPR016082(Ribosomal protein L30, C-terminal)|interpro:IPR012988(Ribosomal protein L30, N-terminal)|interpro:IPR005998(Ribosomal protein L7, eukaryotic)|interpro:IPR039699|interpro:IPR035808|interpro:IPR036919|go:"GO:0000463"("maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)")|go:"GO:0003677"(DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005840"(ribosome)|go:"GO:0005844"(polysome)|go:"GO:0006364"(rRNA processing)|go:"GO:0008097"(5S rRNA binding)|go:"GO:0014069"(postsynaptic density)|go:"GO:0022625"(cytosolic large ribosomal subunit)|go:"GO:0022626"(cytosolic ribosome)|go:"GO:0031672"(A band)|go:"GO:0042273"(ribosomal large subunit biogenesis)|go:"GO:0042802"(identical protein binding)|go:"GO:0045202"(synapse)|go:"GO:0097421"(liver regeneration)|go:"GO:1990904"(ribonucleoprotein complex)|reactome:R-RNO-156827|reactome:R-RNO-1799339|reactome:R-RNO-6791226|reactome:R-RNO-72689|reactome:R-RNO-72706|reactome:R-RNO-975956|reactome:R-RNO-975957|mint:P05426	-	-	-	figure legend:ST1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10116(rat-brain-cerebellum)|taxid:10116(Rattus norvegicus)	-	2020/10/30	2020/10/30	rogid:DtE+ZXAZKdCMvUW5K+jXQ5bH07M10116	rogid:pIpF4885CEJGzSQVuRWK0nx1pgY10116	rigid:OaXQ9NA25fwCWxejPU3Ao9q5j/E	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q5XIE8	uniprotkb:P61354	intact:EBI-15348306|ensembl:ENSRNOP00000023037	intact:EBI-352771|ensembl:ENSRNOP00000028060|uniprotkb:P08526|uniprotkb:Q5BJ97	psi-mi:itm2b_rat(display_long)|uniprotkb:Itm2b(gene name)|psi-mi:Itm2b(display_short)|uniprotkb:Immature BRI2(gene name synonym)|uniprotkb:Transmembrane protein BRI(gene name synonym)	psi-mi:rl27_rat(display_long)|uniprotkb:Rpl27(gene name)|psi-mi:Rpl27(display_short)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Martins et al. (2018)	imex:IM-28469|pubmed:29476059	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26438079|imex:IM-28469-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSRNOG00000016271(gene)|ensembl:ENSRNOT00000023037(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001540"(amyloid-beta binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0010008"(endosome membrane)|go:"GO:0030660"(Golgi-associated vesicle membrane)|go:"GO:0031301"(integral component of organelle membrane)|go:"GO:0042985"(negative regulation of amyloid precursor protein biosynthetic process)|interpro:IPR007084(BRICHOS)|interpro:IPR040145|mint:Q5XIE8|refseq:NP_001006964.1|rgd:620727	reactome:R-RNO-72706|reactome:R-RNO-975956|reactome:R-RNO-975957|reactome:R-RNO-72689|ensembl:ENSRNOG00000020674(gene)|ensembl:ENSRNOT00000028060(transcript)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005840"(ribosome)|go:"GO:0006364"(rRNA processing)|go:"GO:0006412"(translation)|go:"GO:0022625"(cytosolic large ribosomal subunit)|go:"GO:0022626"(cytosolic ribosome)|go:"GO:0098556"(cytoplasmic side of rough endoplasmic reticulum membrane)|go:"GO:1904044"(response to aldosterone)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR001141(Ribosomal protein L27e)|interpro:IPR005824(KOW)|interpro:IPR008991(Translation protein SH3-like)|interpro:IPR018262|interpro:IPR038655|interpro:IPR041991|mint:P61354|reactome:R-RNO-156827|reactome:R-RNO-1799339|reactome:R-RNO-6791226|rgd:621192|refseq:NP_071959.1	-	-	-	figure legend:ST1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10116(rat-brain-cerebellum)|taxid:10116(Rattus norvegicus)	-	2020/10/30	2020/10/30	rogid:DtE+ZXAZKdCMvUW5K+jXQ5bH07M10116	rogid:TLWbAcdRKUb2ijDYjSUa1sbixis10116	rigid:OaXQ9NA25fwCWxejPU3Ao9q5j/E	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q5XIE8	uniprotkb:P38983	intact:EBI-15348306|ensembl:ENSRNOP00000023037	intact:EBI-917451|uniprotkb:B6ZB78|ensembl:ENSRNOP00000025224	psi-mi:itm2b_rat(display_long)|uniprotkb:Itm2b(gene name)|psi-mi:Itm2b(display_short)|uniprotkb:Immature BRI2(gene name synonym)|uniprotkb:Transmembrane protein BRI(gene name synonym)	psi-mi:rssa_rat(display_long)|uniprotkb:Laminin receptor 1(gene name synonym)|uniprotkb:37/67 kDa laminin receptor(gene name synonym)|uniprotkb:Laminin-binding protein precursor p40(gene name synonym)|uniprotkb:Rpsa(gene name)|psi-mi:Rpsa(display_short)|uniprotkb:Lamr1(gene name synonym)|uniprotkb:37 kDa laminin receptor precursor(gene name synonym)|uniprotkb:67 kDa laminin receptor(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Martins et al. (2018)	imex:IM-28469|pubmed:29476059	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26438079|imex:IM-28469-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSRNOG00000016271(gene)|ensembl:ENSRNOT00000023037(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001540"(amyloid-beta binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0010008"(endosome membrane)|go:"GO:0030660"(Golgi-associated vesicle membrane)|go:"GO:0031301"(integral component of organelle membrane)|go:"GO:0042985"(negative regulation of amyloid precursor protein biosynthetic process)|interpro:IPR007084(BRICHOS)|interpro:IPR040145|mint:Q5XIE8|refseq:NP_001006964.1|rgd:620727	rgd:71026|refseq:NP_058834.1|ensembl:ENSRNOG00000018645(gene)|ensembl:ENSRNOT00000025225(transcript)|go:"GO:0000028"(ribosomal small subunit assembly)|go:"GO:0002181"(cytoplasmic translation)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005055"(laminin receptor activity)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005604"(basement membrane)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006412"(translation)|go:"GO:0015935"(small ribosomal subunit)|go:"GO:0016020"(membrane)|go:"GO:0022626"(cytosolic ribosome)|go:"GO:0022627"(cytosolic small ribosomal subunit)|go:"GO:0030855"(epithelial cell differentiation)|go:"GO:0043022"(ribosome binding)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043236"(laminin binding)|go:"GO:0045202"(synapse)|go:"GO:0062023"(collagen-containing extracellular matrix)|go:"GO:0098609"(cell-cell adhesion)|go:"GO:0098978"(glutamatergic synapse)|interpro:IPR001865(Ribosomal protein S2)|interpro:IPR005707(Ribosomal protein S2, eukaryotic/archaeal)|interpro:IPR018130|interpro:IPR023591|interpro:IPR027498|interpro:IPR027504|interpro:IPR032281|mint:P38983|reactome:R-RNO-156827|reactome:R-RNO-1799339|reactome:R-RNO-6791226|reactome:R-RNO-72649|reactome:R-RNO-72689|reactome:R-RNO-72695|reactome:R-RNO-72702|reactome:R-RNO-72706|reactome:R-RNO-975956|reactome:R-RNO-975957	-	-	-	figure legend:ST1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10116(rat-brain-cerebellum)|taxid:10116(Rattus norvegicus)	-	2020/10/30	2020/10/30	rogid:DtE+ZXAZKdCMvUW5K+jXQ5bH07M10116	rogid:XVgtLKyvO/UwRSx+OqV7+lc98XI10116	rigid:OaXQ9NA25fwCWxejPU3Ao9q5j/E	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q5XIE8	uniprotkb:P62703	intact:EBI-15348306|ensembl:ENSRNOP00000023037	intact:EBI-354282|uniprotkb:P12631|uniprotkb:P12750|uniprotkb:P27576|uniprotkb:Q14727|uniprotkb:P55831|ensembl:ENSRNOP00000067969	psi-mi:itm2b_rat(display_long)|uniprotkb:Itm2b(gene name)|psi-mi:Itm2b(display_short)|uniprotkb:Immature BRI2(gene name synonym)|uniprotkb:Transmembrane protein BRI(gene name synonym)	psi-mi:rs4x_rat(display_long)|uniprotkb:Rps4x(gene name)|psi-mi:Rps4x(display_short)|uniprotkb:Rps4(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Martins et al. (2018)	imex:IM-28469|pubmed:29476059	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26438079|imex:IM-28469-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSRNOG00000016271(gene)|ensembl:ENSRNOT00000023037(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001540"(amyloid-beta binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0010008"(endosome membrane)|go:"GO:0030660"(Golgi-associated vesicle membrane)|go:"GO:0031301"(integral component of organelle membrane)|go:"GO:0042985"(negative regulation of amyloid precursor protein biosynthetic process)|interpro:IPR007084(BRICHOS)|interpro:IPR040145|mint:Q5XIE8|refseq:NP_001006964.1|rgd:620727	refseq:NP_001007601.1|rgd:2324318|ensembl:ENSRNOG00000003201(gene)|go:"GO:0019843"(rRNA binding)|go:"GO:0022626"(cytosolic ribosome)|go:"GO:0022627"(cytosolic small ribosomal subunit)|go:"GO:0036464"(cytoplasmic ribonucleoprotein granule)|go:"GO:0045202"(synapse)|go:"GO:0045471"(response to ethanol)|ensembl:ENSRNOT00000076978(transcript)|go:"GO:0045727"(positive regulation of translation)|go:"GO:0003723"(RNA binding)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005840"(ribosome)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR000876(Ribosomal protein S4e)|interpro:IPR002942(RNA-binding S4)|interpro:IPR005824(KOW)|interpro:IPR013843(Ribosomal protein S4e, N-terminal)|interpro:IPR013845(Ribosomal protein S4e, central)|go:"GO:0005844"(polysome)|go:"GO:0006412"(translation)|interpro:IPR014722(Translation protein SH3-like, subgroup)|interpro:IPR018199|interpro:IPR032277|interpro:IPR036986|interpro:IPR038237|interpro:IPR041982|mint:P62703|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0015935"(small ribosomal subunit)|reactome:R-RNO-156827|reactome:R-RNO-1799339|reactome:R-RNO-6791226|reactome:R-RNO-72649|reactome:R-RNO-72689|reactome:R-RNO-72695|reactome:R-RNO-72702|reactome:R-RNO-72706|reactome:R-RNO-975956|reactome:R-RNO-975957	-	-	-	figure legend:ST1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10116(rat-brain-cerebellum)|taxid:10116(Rattus norvegicus)	-	2020/10/30	2020/10/30	rogid:DtE+ZXAZKdCMvUW5K+jXQ5bH07M10116	rogid:2ZuLXqBSDkK0CtN3mnIDoFAR8yI10116	rigid:OaXQ9NA25fwCWxejPU3Ao9q5j/E	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q5XIE8	uniprotkb:P17074	intact:EBI-15348306|ensembl:ENSRNOP00000023037	intact:EBI-916692|ensembl:ENSRNOP00000027246	psi-mi:itm2b_rat(display_long)|uniprotkb:Itm2b(gene name)|psi-mi:Itm2b(display_short)|uniprotkb:Immature BRI2(gene name synonym)|uniprotkb:Transmembrane protein BRI(gene name synonym)	psi-mi:rs19_rat(display_long)|uniprotkb:Rps19(gene name)|psi-mi:Rps19(display_short)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Martins et al. (2018)	imex:IM-28469|pubmed:29476059	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26438079|imex:IM-28469-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSRNOG00000016271(gene)|ensembl:ENSRNOT00000023037(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001540"(amyloid-beta binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0010008"(endosome membrane)|go:"GO:0030660"(Golgi-associated vesicle membrane)|go:"GO:0031301"(integral component of organelle membrane)|go:"GO:0042985"(negative regulation of amyloid precursor protein biosynthetic process)|interpro:IPR007084(BRICHOS)|interpro:IPR040145|mint:Q5XIE8|refseq:NP_001006964.1|rgd:620727	rgd:68440|refseq:NP_001032423.1|refseq:XP_006228473.1|refseq:XP_017444775.1|refseq:XP_017444777.1|refseq:XP_017445502.1|ensembl:ENSRNOG00000037897(gene)|ensembl:ENSRNOT00000027246(transcript)|go:"GO:0000028"(ribosomal small subunit assembly)|go:"GO:0003723"(RNA binding)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005730"(nucleolus)|go:"GO:0006412"(translation)|go:"GO:0007219"(Notch signaling pathway)|go:"GO:0022627"(cytosolic small ribosomal subunit)|go:"GO:0030218"(erythrocyte differentiation)|go:"GO:0031369"(translation initiation factor binding)|go:"GO:0045202"(synapse)|interpro:IPR001266(Ribosomal protein S19e)|interpro:IPR018277|interpro:IPR036388|interpro:IPR036390|mint:P17074|reactome:R-RNO-156827|reactome:R-RNO-1799339|reactome:R-RNO-6791226|reactome:R-RNO-72649|reactome:R-RNO-72689|reactome:R-RNO-72695|reactome:R-RNO-72702|reactome:R-RNO-72706|reactome:R-RNO-975956|reactome:R-RNO-975957	-	-	-	figure legend:ST1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10116(rat-brain-cerebellum)|taxid:10116(Rattus norvegicus)	-	2020/10/30	2020/10/30	rogid:DtE+ZXAZKdCMvUW5K+jXQ5bH07M10116	rogid:D3A6ULv7RIjBdw3qPwrdoWZ+F4U10116	rigid:OaXQ9NA25fwCWxejPU3Ao9q5j/E	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q5XIE8	uniprotkb:P62250	intact:EBI-15348306|ensembl:ENSRNOP00000023037	intact:EBI-352489|uniprotkb:P17008|ensembl:ENSRNOP00000026576	psi-mi:itm2b_rat(display_long)|uniprotkb:Itm2b(gene name)|psi-mi:Itm2b(display_short)|uniprotkb:Immature BRI2(gene name synonym)|uniprotkb:Transmembrane protein BRI(gene name synonym)	psi-mi:rs16_rat(display_long)|uniprotkb:Rps16(gene name)|psi-mi:Rps16(display_short)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Martins et al. (2018)	imex:IM-28469|pubmed:29476059	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26438079|imex:IM-28469-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSRNOG00000016271(gene)|ensembl:ENSRNOT00000023037(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001540"(amyloid-beta binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0010008"(endosome membrane)|go:"GO:0030660"(Golgi-associated vesicle membrane)|go:"GO:0031301"(integral component of organelle membrane)|go:"GO:0042985"(negative regulation of amyloid precursor protein biosynthetic process)|interpro:IPR007084(BRICHOS)|interpro:IPR040145|mint:Q5XIE8|refseq:NP_001006964.1|rgd:620727	rgd:621031|refseq:NP_001162617.1|ensembl:ENSRNOG00000019578(gene)|ensembl:ENSRNOT00000026576(transcript)|go:"GO:0000462"("maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)")|go:"GO:0003723"(RNA binding)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0006364"(rRNA processing)|go:"GO:0006412"(translation)|go:"GO:0015935"(small ribosomal subunit)|go:"GO:0022626"(cytosolic ribosome)|go:"GO:0022627"(cytosolic small ribosomal subunit)|go:"GO:0042274"(ribosomal small subunit biogenesis)|go:"GO:0097421"(liver regeneration)|go:"GO:1990830"(cellular response to leukemia inhibitory factor)|interpro:IPR000754(Ribosomal protein S9)|interpro:IPR014721(Ribosomal protein S5 domain 2-type fold)|interpro:IPR020568|interpro:IPR020574|mint:P62250|reactome:R-RNO-156827|reactome:R-RNO-1799339|reactome:R-RNO-6791226|reactome:R-RNO-72649|reactome:R-RNO-72689|reactome:R-RNO-72695|reactome:R-RNO-72702|reactome:R-RNO-72706|reactome:R-RNO-975956|reactome:R-RNO-975957	-	-	-	figure legend:ST1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10116(rat-brain-cerebellum)|taxid:10116(Rattus norvegicus)	-	2020/10/30	2020/10/30	rogid:DtE+ZXAZKdCMvUW5K+jXQ5bH07M10116	rogid:OrKriR6HsATLaO+drdUa2w3Gpd010116	rigid:OaXQ9NA25fwCWxejPU3Ao9q5j/E	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q5XIE8	uniprotkb:P62278	intact:EBI-15348306|ensembl:ENSRNOP00000023037	intact:EBI-351861|uniprotkb:P19116|uniprotkb:Q02546|uniprotkb:Q29200|ensembl:ENSRNOP00000036690	psi-mi:itm2b_rat(display_long)|uniprotkb:Itm2b(gene name)|psi-mi:Itm2b(display_short)|uniprotkb:Immature BRI2(gene name synonym)|uniprotkb:Transmembrane protein BRI(gene name synonym)	psi-mi:rs13_rat(display_long)|uniprotkb:Rps13(gene name)|psi-mi:Rps13(display_short)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Martins et al. (2018)	imex:IM-28469|pubmed:29476059	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26438079|imex:IM-28469-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSRNOG00000016271(gene)|ensembl:ENSRNOT00000023037(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001540"(amyloid-beta binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0010008"(endosome membrane)|go:"GO:0030660"(Golgi-associated vesicle membrane)|go:"GO:0031301"(integral component of organelle membrane)|go:"GO:0042985"(negative regulation of amyloid precursor protein biosynthetic process)|interpro:IPR007084(BRICHOS)|interpro:IPR040145|mint:Q5XIE8|refseq:NP_001006964.1|rgd:620727	rgd:621027|refseq:NP_569116.1|refseq:XP_001053043.1|ensembl:ENSRNOG00000028021(gene)|ensembl:ENSRNOT00000034694(transcript)|go:"GO:0003729"(mRNA binding)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005634"(nucleus)|go:"GO:0005730"(nucleolus)|go:"GO:0006412"(translation)|go:"GO:0014069"(postsynaptic density)|go:"GO:0022626"(cytosolic ribosome)|go:"GO:0022627"(cytosolic small ribosomal subunit)|go:"GO:0033119"(negative regulation of RNA splicing)|go:"GO:0045202"(synapse)|go:"GO:0048027"(mRNA 5'-UTR binding)|go:"GO:0070181"(small ribosomal subunit rRNA binding)|go:"GO:1990932"(5.8S rRNA binding)|interpro:IPR000589(Ribosomal protein S15)|interpro:IPR009068(S15/NS1, RNA-binding)|interpro:IPR012606(Ribosomal protein S13/S15, N-terminal)|interpro:IPR023029|mint:P62278|reactome:R-RNO-156827|reactome:R-RNO-1799339|reactome:R-RNO-6791226|reactome:R-RNO-72649|reactome:R-RNO-72689|reactome:R-RNO-72695|reactome:R-RNO-72702|reactome:R-RNO-72706|reactome:R-RNO-975956|reactome:R-RNO-975957|refseq:XP_003753737.1	-	-	-	figure legend:ST1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10116(rat-brain-cerebellum)|taxid:10116(Rattus norvegicus)	-	2020/10/30	2020/10/30	rogid:DtE+ZXAZKdCMvUW5K+jXQ5bH07M10116	rogid:GmlWYkXKxX6YwpEtzNABb+ZcytI10116	rigid:OaXQ9NA25fwCWxejPU3Ao9q5j/E	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q5XIE8	uniprotkb:Q4FZT9	intact:EBI-15348306|ensembl:ENSRNOP00000023037	intact:EBI-2640482|ensembl:ENSRNOP00000002358	psi-mi:itm2b_rat(display_long)|uniprotkb:Itm2b(gene name)|psi-mi:Itm2b(display_short)|uniprotkb:Immature BRI2(gene name synonym)|uniprotkb:Transmembrane protein BRI(gene name synonym)	psi-mi:psmd2_rat(display_long)|uniprotkb:Psmd2(gene name)|psi-mi:Psmd2(display_short)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Martins et al. (2018)	imex:IM-28469|pubmed:29476059	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26438079|imex:IM-28469-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSRNOG00000016271(gene)|ensembl:ENSRNOT00000023037(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001540"(amyloid-beta binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0010008"(endosome membrane)|go:"GO:0030660"(Golgi-associated vesicle membrane)|go:"GO:0031301"(integral component of organelle membrane)|go:"GO:0042985"(negative regulation of amyloid precursor protein biosynthetic process)|interpro:IPR007084(BRICHOS)|interpro:IPR040145|mint:Q5XIE8|refseq:NP_001006964.1|rgd:620727	rgd:1305752|refseq:NP_001026809.1|reactome:R-RNO-69601|reactome:R-RNO-75815|reactome:R-RNO-8852276|reactome:R-RNO-8951664|reactome:R-RNO-983168|reactome:R-RNO-8854050|reactome:R-RNO-8932339|reactome:R-RNO-8939236|reactome:R-RNO-8941858|reactome:R-RNO-8948751|ensembl:ENSRNOG00000001719(gene)|ensembl:ENSRNOT00000002358(transcript)|go:"GO:0000502"(proteasome complex)|go:"GO:0005634"(nucleus)|go:"GO:0005838"(proteasome regulatory particle)|go:"GO:0008540"(proteasome regulatory particle, base subcomplex)|go:"GO:0022624"(proteasome accessory complex)|go:"GO:0030234"(enzyme regulator activity)|go:"GO:0034515"(proteasome storage granule)|go:"GO:0042176"(regulation of protein catabolic process)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|interpro:IPR002015(Proteasome/cyclosome, regulatory subunit)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR016643(26S proteasome regulatory complex, non-ATPase subcomplex, Rpn1 subunit)|interpro:IPR040892|interpro:IPR041433|mint:Q4FZT9|rcsb pdb:6EPC|rcsb pdb:6EPD|rcsb pdb:6EPE|rcsb pdb:6EPF|reactome:R-RNO-1169091|reactome:R-RNO-1234176|reactome:R-RNO-1236978|reactome:R-RNO-174084|reactome:R-RNO-174154|reactome:R-RNO-174178|reactome:R-RNO-174184|reactome:R-RNO-187577|reactome:R-RNO-195253|reactome:R-RNO-2467813|reactome:R-RNO-349425|reactome:R-RNO-350562|reactome:R-RNO-382556|reactome:R-RNO-450408|reactome:R-RNO-4608870|reactome:R-RNO-4641257|reactome:R-RNO-4641258|reactome:R-RNO-5358346|reactome:R-RNO-5607761|reactome:R-RNO-5610780|reactome:R-RNO-5610785|reactome:R-RNO-5632684|reactome:R-RNO-5658442|reactome:R-RNO-5668541|reactome:R-RNO-5676590|reactome:R-RNO-5687128|reactome:R-RNO-5689603|reactome:R-RNO-5689880|reactome:R-RNO-6798695|reactome:R-RNO-68827|reactome:R-RNO-68949|reactome:R-RNO-69017|reactome:R-RNO-69481	-	-	-	figure legend:ST1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10116(rat-brain-cerebellum)|taxid:10116(Rattus norvegicus)	-	2020/10/30	2020/10/30	rogid:DtE+ZXAZKdCMvUW5K+jXQ5bH07M10116	rogid:RLdXL5kvmBPO1OIhqHL/NoXaeCo10116	rigid:OaXQ9NA25fwCWxejPU3Ao9q5j/E	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q5XIE8	uniprotkb:P63081	intact:EBI-15348306|ensembl:ENSRNOP00000023037	intact:EBI-2025009|uniprotkb:P23967|ensembl:ENSRNOP00000008736	psi-mi:itm2b_rat(display_long)|uniprotkb:Itm2b(gene name)|psi-mi:Itm2b(display_short)|uniprotkb:Immature BRI2(gene name synonym)|uniprotkb:Transmembrane protein BRI(gene name synonym)	psi-mi:vatl_rat(display_long)|uniprotkb:Atp6v0c(gene name)|psi-mi:Atp6v0c(display_short)|uniprotkb:Atp6c(gene name synonym)|uniprotkb:Atp6l(gene name synonym)|uniprotkb:Atpl(gene name synonym)|uniprotkb:Vacuolar proton pump 16 kDa proteolipid subunit(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Martins et al. (2018)	imex:IM-28469|pubmed:29476059	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26438079|imex:IM-28469-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSRNOG00000016271(gene)|ensembl:ENSRNOT00000023037(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001540"(amyloid-beta binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0010008"(endosome membrane)|go:"GO:0030660"(Golgi-associated vesicle membrane)|go:"GO:0031301"(integral component of organelle membrane)|go:"GO:0042985"(negative regulation of amyloid precursor protein biosynthetic process)|interpro:IPR007084(BRICHOS)|interpro:IPR040145|mint:Q5XIE8|refseq:NP_001006964.1|rgd:620727	rgd:621394|refseq:NP_570836.1|refseq:XP_006245960.1|ensembl:ENSRNOG00000006542(gene)|ensembl:ENSRNOT00000008736(transcript)|go:"GO:0005764"(lysosome)|go:"GO:0005774"(vacuolar membrane)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030177"(positive regulation of Wnt signaling pathway)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0033179"(proton-transporting V-type ATPase, V0 domain)|go:"GO:0046961"(proton-transporting ATPase activity, rotational mechanism)|go:"GO:0070374"(positive regulation of ERK1 and ERK2 cascade)|go:"GO:1904093"(negative regulation of autophagic cell death)|interpro:IPR000245(ATPase, V0 complex, proteolipid subunit C,)|interpro:IPR002379(ATPase, F0/V0 complex, subunit C)|interpro:IPR011555(ATPase, V0 complex, proteolipid subunit C, eukaryotic)|interpro:IPR035921|mint:P63081|rcsb pdb:6VQ6|rcsb pdb:6VQ7|rcsb pdb:6VQ8|rcsb pdb:6VQC|rcsb pdb:6VQG|rcsb pdb:6VQH|reactome:R-RNO-1222556|reactome:R-RNO-6798695|reactome:R-RNO-77387|reactome:R-RNO-917977|reactome:R-RNO-9639288|reactome:R-RNO-983712	-	-	-	figure legend:ST1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10116(rat-brain-cerebellum)|taxid:10116(Rattus norvegicus)	-	2020/10/30	2020/10/30	rogid:DtE+ZXAZKdCMvUW5K+jXQ5bH07M10116	rogid:Qx4BtXXIXdTlTTWE3nBHM8kThHU10116	rigid:OaXQ9NA25fwCWxejPU3Ao9q5j/E	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q5XIE8	uniprotkb:P25286	intact:EBI-15348306|ensembl:ENSRNOP00000023037	intact:EBI-2024887|intact:EBI-11702593	psi-mi:itm2b_rat(display_long)|uniprotkb:Itm2b(gene name)|psi-mi:Itm2b(display_short)|uniprotkb:Immature BRI2(gene name synonym)|uniprotkb:Transmembrane protein BRI(gene name synonym)	psi-mi:vpp1_rat(display_long)|uniprotkb:Atp6v0a1(gene name)|psi-mi:Atp6v0a1(display_short)|uniprotkb:Atp6n1(gene name synonym)|uniprotkb:Vpp1(gene name synonym)|uniprotkb:Vacuolar proton translocating ATPase 116 kDa subunit a isoform 1(gene name synonym)|uniprotkb:Clathrin-coated vesicle/synaptic vesicle proton pump 116 kDa subunit(gene name synonym)|uniprotkb:Vacuolar proton pump subunit 1(gene name synonym)|uniprotkb:Vacuolar adenosine triphosphatase subunit Ac116(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Martins et al. (2018)	imex:IM-28469|pubmed:29476059	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26438079|imex:IM-28469-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSRNOG00000016271(gene)|ensembl:ENSRNOT00000023037(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001540"(amyloid-beta binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0010008"(endosome membrane)|go:"GO:0030660"(Golgi-associated vesicle membrane)|go:"GO:0031301"(integral component of organelle membrane)|go:"GO:0042985"(negative regulation of amyloid precursor protein biosynthetic process)|interpro:IPR007084(BRICHOS)|interpro:IPR040145|mint:Q5XIE8|refseq:NP_001006964.1|rgd:620727	interpro:IPR026028|interpro:IPR002490(ATPase, V0/A0 complex, 116-kDa subunit)|rgd:68405|refseq:NP_113792.2|mint:P25286|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0007035"(vacuolar acidification)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0016241"(regulation of macroautophagy)|go:"GO:0016471"(vacuolar proton-transporting V-type ATPase complex)|go:"GO:0030285"(integral component of synaptic vesicle membrane)|go:"GO:0042470"(melanosome)|go:"GO:0043195"(terminal bouton)|go:"GO:0043229"(intracellular organelle)|go:"GO:0046961"(proton-transporting ATPase activity, rotational mechanism)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051117"(ATPase binding)|go:"GO:1901998"(toxin transport)|rcsb pdb:6VQ6|rcsb pdb:6VQ7|rcsb pdb:6VQ8|rcsb pdb:6VQC|rcsb pdb:6VQG|rcsb pdb:6VQH|rcsb pdb:6VQI|rcsb pdb:6VQJ|rcsb pdb:6VQK|reactome:R-RNO-1222556|reactome:R-RNO-6798695|reactome:R-RNO-77387|reactome:R-RNO-917977|reactome:R-RNO-983712|go:"GO:0000220"(vacuolar proton-transporting V-type ATPase, V0 domain)	-	-	-	figure legend:ST1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10116(rat-brain-cerebellum)|taxid:10116(Rattus norvegicus)	-	2020/10/30	2020/10/30	rogid:DtE+ZXAZKdCMvUW5K+jXQ5bH07M10116	rogid:M+mzcb5KThafTTcJpimDmH5I4fk10116	rigid:OaXQ9NA25fwCWxejPU3Ao9q5j/E	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q5XIE8	uniprotkb:Q9R1Z0	intact:EBI-15348306|ensembl:ENSRNOP00000023037	intact:EBI-2255834|uniprotkb:Q6GSZ1|uniprotkb:Q9ESR2|uniprotkb:Q9JI31|uniprotkb:Q9WTU2	psi-mi:itm2b_rat(display_long)|uniprotkb:Itm2b(gene name)|psi-mi:Itm2b(display_short)|uniprotkb:Immature BRI2(gene name synonym)|uniprotkb:Transmembrane protein BRI(gene name synonym)	psi-mi:vdac3_rat(display_long)|uniprotkb:Vdac3(gene name)|psi-mi:Vdac3(display_short)|uniprotkb:Outer mitochondrial membrane protein porin 3(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Martins et al. (2018)	imex:IM-28469|pubmed:29476059	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26438079|imex:IM-28469-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSRNOG00000016271(gene)|ensembl:ENSRNOT00000023037(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001540"(amyloid-beta binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0010008"(endosome membrane)|go:"GO:0030660"(Golgi-associated vesicle membrane)|go:"GO:0031301"(integral component of organelle membrane)|go:"GO:0042985"(negative regulation of amyloid precursor protein biosynthetic process)|interpro:IPR007084(BRICHOS)|interpro:IPR040145|mint:Q5XIE8|refseq:NP_001006964.1|rgd:620727	rgd:621577|refseq:NP_112645.1|interpro:IPR001925(Porin, eukaryotic type)|interpro:IPR030271|interpro:IPR027246|mint:Q9R1Z0|interpro:IPR023614|go:"GO:0000166"(nucleotide binding)|go:"GO:0001662"(behavioral fear response)|go:"GO:0005739"(mitochondrion)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005791"(rough endoplasmic reticulum)|go:"GO:0007268"(chemical synaptic transmission)|go:"GO:0007270"(neuron-neuron synaptic transmission)|go:"GO:0007612"(learning)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0008308"(voltage-gated anion channel activity)|go:"GO:0015288"(porin activity)|go:"GO:0016020"(membrane)|go:"GO:0046930"(pore complex)|go:"GO:1902017"(regulation of cilium assembly)|reactome:R-RNO-5689880	-	-	-	figure legend:ST1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10116(rat-brain-cerebellum)|taxid:10116(Rattus norvegicus)	-	2020/10/30	2020/10/30	rogid:DtE+ZXAZKdCMvUW5K+jXQ5bH07M10116	rogid:32zwKuZVCTarCx4d4bMt6Apc6cE10116	rigid:OaXQ9NA25fwCWxejPU3Ao9q5j/E	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q5XIE8	uniprotkb:Q9JJW3	intact:EBI-15348306|ensembl:ENSRNOP00000023037	intact:EBI-26437382|ensembl:ENSRNOP00000027496|ensembl:ENSRNOP00000061817	psi-mi:itm2b_rat(display_long)|uniprotkb:Itm2b(gene name)|psi-mi:Itm2b(display_short)|uniprotkb:Immature BRI2(gene name synonym)|uniprotkb:Transmembrane protein BRI(gene name synonym)	psi-mi:atpmk_rat(display_long)|uniprotkb:Atp5mk(gene name)|psi-mi:Atp5mk(display_short)|uniprotkb:ATP synthase membrane subunit DAPIT, mitochondrial(gene name synonym)|uniprotkb:Atp5md(gene name synonym)|uniprotkb:Dapit(gene name synonym)|uniprotkb:Diabetes-associated protein in insulin-sensitive tissues(gene name synonym)|uniprotkb:Up-regulated during skeletal muscle growth protein 5(gene name synonym)|uniprotkb:Usmg5(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Martins et al. (2018)	imex:IM-28469|pubmed:29476059	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26438079|imex:IM-28469-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSRNOG00000016271(gene)|ensembl:ENSRNOT00000023037(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001540"(amyloid-beta binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0010008"(endosome membrane)|go:"GO:0030660"(Golgi-associated vesicle membrane)|go:"GO:0031301"(integral component of organelle membrane)|go:"GO:0042985"(negative regulation of amyloid precursor protein biosynthetic process)|interpro:IPR007084(BRICHOS)|interpro:IPR040145|mint:Q5XIE8|refseq:NP_001006964.1|rgd:620727	ensembl:ENSRNOG00000020296(gene)|ensembl:ENSRNOG00000042869(gene)|ensembl:ENSRNOT00000027496(transcript)|ensembl:ENSRNOT00000064931(transcript)|go:"GO:0005739"(mitochondrion)|go:"GO:0005753"(mitochondrial proton-transporting ATP synthase complex)|go:"GO:0016021"(integral component of membrane)|interpro:IPR009125(DAPIT)|mint:Q9JJW3|refseq:NP_598228.1|refseq:XP_008766441.1|refseq:XP_008773622.1|rgd:631426	-	-	-	figure legend:ST1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10116(rat-brain-cerebellum)|taxid:10116(Rattus norvegicus)	-	2020/10/30	2020/10/30	rogid:DtE+ZXAZKdCMvUW5K+jXQ5bH07M10116	rogid:PeUvTdLYLEDd4wXYTYtUyyslllY10116	rigid:OaXQ9NA25fwCWxejPU3Ao9q5j/E	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q5XIE8	uniprotkb:P11167	intact:EBI-15348306|ensembl:ENSRNOP00000023037	intact:EBI-960654|ensembl:ENSRNOP00000061340	psi-mi:itm2b_rat(display_long)|uniprotkb:Itm2b(gene name)|psi-mi:Itm2b(display_short)|uniprotkb:Immature BRI2(gene name synonym)|uniprotkb:Transmembrane protein BRI(gene name synonym)	psi-mi:gtr1_rat(display_long)|uniprotkb:Slc2a1(gene name)|psi-mi:Slc2a1(display_short)|uniprotkb:Glut1(gene name synonym)|uniprotkb:Glucose transporter type 1, erythrocyte/brain(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Martins et al. (2018)	imex:IM-28469|pubmed:29476059	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26438079|imex:IM-28469-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSRNOG00000016271(gene)|ensembl:ENSRNOT00000023037(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001540"(amyloid-beta binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0010008"(endosome membrane)|go:"GO:0030660"(Golgi-associated vesicle membrane)|go:"GO:0031301"(integral component of organelle membrane)|go:"GO:0042985"(negative regulation of amyloid precursor protein biosynthetic process)|interpro:IPR007084(BRICHOS)|interpro:IPR040145|mint:Q5XIE8|refseq:NP_001006964.1|rgd:620727	ensembl:ENSRNOG00000007284(gene)|ensembl:ENSRNOT00000064452(transcript)|go:"GO:0001666"(response to hypoxia)|go:"GO:0001917"(photoreceptor inner segment)|go:"GO:0001939"(female pronucleus)|go:"GO:0005324"(long-chain fatty acid transporter activity)|go:"GO:0005355"(glucose transmembrane transporter activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0005901"(caveola)|go:"GO:0005911"(cell-cell junction)|go:"GO:0006970"(response to osmotic stress)|go:"GO:0007417"(central nervous system development)|go:"GO:0007565"(female pregnancy)|go:"GO:0014704"(intercalated disc)|go:"GO:0015911"(long-chain fatty acid import across plasma membrane)|go:"GO:0016020"(membrane)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0019900"(kinase binding)|go:"GO:0021987"(cerebral cortex development)|go:"GO:0030018"(Z disc)|go:"GO:0030496"(midbody)|go:"GO:0030864"(cortical actin cytoskeleton)|go:"GO:0032868"(response to insulin)|go:"GO:0033300"(dehydroascorbic acid transmembrane transporter activity)|go:"GO:0042149"(cellular response to glucose starvation)|go:"GO:0042383"(sarcolemma)|go:"GO:0042802"(identical protein binding)|go:"GO:0042908"(xenobiotic transport)|go:"GO:0042910"(xenobiotic transmembrane transporter activity)|go:"GO:0043621"(protein self-association)|go:"GO:0045121"(membrane raft)|go:"GO:0031982"(vesicle)|go:"GO:0045202"(synapse)|go:"GO:0045494"(photoreceptor cell maintenance)|go:"GO:0055056"(D-glucose transmembrane transporter activity)|go:"GO:0065003"(protein-containing complex assembly)|go:"GO:0070837"(dehydroascorbic acid transport)|go:"GO:0071260"(cellular response to mechanical stimulus)|go:"GO:0071474"(cellular hyperosmotic response)|go:"GO:0098708"(glucose import across plasma membrane)|go:"GO:0098793"(presynapse)|go:"GO:0150104"(transport across blood-brain barrier)|go:"GO:1904016"(response to Thyroglobulin triiodothyronine)|go:"GO:1904659"(glucose transmembrane transport)|interpro:IPR002439("Glucose transporter, type 1 (GLUT1)")|interpro:IPR003663(Sugar transporter)|interpro:IPR005828(General substrate transporter)|interpro:IPR005829(Sugar transporter, conserved site)|interpro:IPR020846|interpro:IPR036259|mint:P11167|reactome:R-RNO-189200|reactome:R-RNO-422356|reactome:R-RNO-5653890|reactome:R-RNO-196836|rgd:3704|refseq:NP_620182.1	-	-	-	figure legend:ST1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10116(rat-brain-cerebellum)|taxid:10116(Rattus norvegicus)	-	2020/10/30	2020/10/30	rogid:DtE+ZXAZKdCMvUW5K+jXQ5bH07M10116	rogid:JriqkyQOrkEOA8WptfkF8G5sD2w10116	rigid:OaXQ9NA25fwCWxejPU3Ao9q5j/E	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q5XIE8	uniprotkb:P13638	intact:EBI-15348306|ensembl:ENSRNOP00000023037	intact:EBI-26437335	psi-mi:itm2b_rat(display_long)|uniprotkb:Itm2b(gene name)|psi-mi:Itm2b(display_short)|uniprotkb:Immature BRI2(gene name synonym)|uniprotkb:Transmembrane protein BRI(gene name synonym)	psi-mi:at1b2_rat(display_long)|uniprotkb:Atp1b2(gene name)|psi-mi:Atp1b2(display_short)|uniprotkb:Sodium/potassium-dependent ATPase subunit beta-2(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Martins et al. (2018)	imex:IM-28469|pubmed:29476059	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26438079|imex:IM-28469-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSRNOG00000016271(gene)|ensembl:ENSRNOT00000023037(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001540"(amyloid-beta binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0010008"(endosome membrane)|go:"GO:0030660"(Golgi-associated vesicle membrane)|go:"GO:0031301"(integral component of organelle membrane)|go:"GO:0042985"(negative regulation of amyloid precursor protein biosynthetic process)|interpro:IPR007084(BRICHOS)|interpro:IPR040145|mint:Q5XIE8|refseq:NP_001006964.1|rgd:620727	go:"GO:0120036"(plasma membrane bounded cell projection organization)|go:"GO:1901018"(positive regulation of potassium ion transmembrane transporter activity)|go:"GO:1903278"(positive regulation of sodium ion export across plasma membrane)|go:"GO:1903288"(positive regulation of potassium ion import across plasma membrane)|go:"GO:1903976"(negative regulation of glial cell migration)|go:"GO:1990573"(potassium ion import across plasma membrane)|reactome:R-RNO-210991|reactome:R-RNO-5578775|reactome:R-RNO-936837|go:"GO:0098984"(neuron to neuron synapse)|go:"GO:0001671"(ATPase activator activity)|go:"GO:0001895"(retina homeostasis)|go:"GO:0001917"(photoreceptor inner segment)|go:"GO:0005391"("P-type sodium:potassium-exchanging transporter activity")|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0005890"("sodium:potassium-exchanging ATPase complex")|go:"GO:0006883"(cellular sodium ion homeostasis)|go:"GO:0009897"(external side of plasma membrane)|go:"GO:0010976"(positive regulation of neuron projection development)|go:"GO:0016020"(membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0016328"(lateral plasma membrane)|go:"GO:0021670"(lateral ventricle development)|go:"GO:0021678"(third ventricle development)|go:"GO:0021944"(neuronal-glial interaction involved in hindbrain glial-mediated radial cell migration)|go:"GO:0030007"(cellular potassium ion homeostasis)|go:"GO:0030674"(protein-macromolecule adaptor activity)|go:"GO:0031253"(cell projection membrane)|go:"GO:0031589"(cell-substrate adhesion)|go:"GO:0032781"(positive regulation of ATP-dependent activity)|go:"GO:0036376"(sodium ion export across plasma membrane)|go:"GO:0044298"(cell body membrane)|go:"GO:0045494"(photoreceptor cell maintenance)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0050821"(protein stabilization)|go:"GO:0051117"(ATPase binding)|go:"GO:0061744"(motor behavior)|go:"GO:0071944"(cell periphery)|go:"GO:0086009"(membrane repolarization)|go:"GO:0097449"(astrocyte projection)|go:"GO:0097450"(astrocyte end-foot)|mint:P13638|interpro:IPR000402(ATPase, P-type cation exchange, beta subunit)|interpro:IPR038702|rgd:2171	-	-	-	figure legend:ST1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10116(rat-brain-cerebellum)|taxid:10116(Rattus norvegicus)	-	2020/10/30	2020/10/30	rogid:DtE+ZXAZKdCMvUW5K+jXQ5bH07M10116	rogid:bl1sa8rfoB1To7Q5na/Mx5QU8Mw10116	rigid:OaXQ9NA25fwCWxejPU3Ao9q5j/E	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q5XIE8	uniprotkb:P07340	intact:EBI-15348306|ensembl:ENSRNOP00000023037	intact:EBI-2640714|uniprotkb:Q63062|ensembl:ENSRNOP00000003932	psi-mi:itm2b_rat(display_long)|uniprotkb:Itm2b(gene name)|psi-mi:Itm2b(display_short)|uniprotkb:Immature BRI2(gene name synonym)|uniprotkb:Transmembrane protein BRI(gene name synonym)	psi-mi:at1b1_rat(display_long)|uniprotkb:Atp1b1(gene name)|psi-mi:Atp1b1(display_short)|uniprotkb:Sodium/potassium-dependent ATPase subunit beta-1(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Martins et al. (2018)	imex:IM-28469|pubmed:29476059	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26438079|imex:IM-28469-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSRNOG00000016271(gene)|ensembl:ENSRNOT00000023037(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001540"(amyloid-beta binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0010008"(endosome membrane)|go:"GO:0030660"(Golgi-associated vesicle membrane)|go:"GO:0031301"(integral component of organelle membrane)|go:"GO:0042985"(negative regulation of amyloid precursor protein biosynthetic process)|interpro:IPR007084(BRICHOS)|interpro:IPR040145|mint:Q5XIE8|refseq:NP_001006964.1|rgd:620727	rgd:2170|refseq:NP_037245.2|ensembl:ENSRNOG00000002934(gene)|ensembl:ENSRNOT00000003932(transcript)|go:"GO:0001666"(response to hypoxia)|go:"GO:0001671"(ATPase activator activity)|go:"GO:0001824"(blastocyst development)|go:"GO:0005391"("P-type sodium:potassium-exchanging transporter activity")|go:"GO:0005886"(plasma membrane)|go:"GO:0005890"("sodium:potassium-exchanging ATPase complex")|go:"GO:0005901"(caveola)|go:"GO:0006813"(potassium ion transport)|go:"GO:0006814"(sodium ion transport)|go:"GO:0006874"(cellular calcium ion homeostasis)|go:"GO:0006883"(cellular sodium ion homeostasis)|go:"GO:0007155"(cell adhesion)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0010882"(regulation of cardiac muscle contraction by calcium ion signaling)|go:"GO:0050821"(protein stabilization)|go:"GO:0051117"(ATPase binding)|go:"GO:0055119"(relaxation of cardiac muscle)|go:"GO:0060048"(cardiac muscle contraction)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0086009"(membrane repolarization)|go:"GO:0098655"(cation transmembrane transport)|go:"GO:1901018"(positive regulation of potassium ion transmembrane transporter activity)|go:"GO:1903169"(regulation of calcium ion transmembrane transport)|go:"GO:0014704"(intercalated disc)|go:"GO:0016020"(membrane)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0016328"(lateral plasma membrane)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030001"(metal ion transport)|go:"GO:1903278"(positive regulation of sodium ion export across plasma membrane)|go:"GO:0030007"(cellular potassium ion homeostasis)|go:"GO:1903281"("positive regulation of calcium:sodium antiporter activity")|go:"GO:1903288"(positive regulation of potassium ion import across plasma membrane)|go:"GO:0030315"(T-tubule)|go:"GO:1903408"("positive regulation of P-type sodium:potassium-exchanging transporter activity")|go:"GO:0030674"(protein-macromolecule adaptor activity)|go:"GO:0031090"(organelle membrane)|go:"GO:0032781"(positive regulation of ATP-dependent activity)|go:"GO:0035725"(sodium ion transmembrane transport)|go:"GO:0036126"(sperm flagellum)|go:"GO:0036376"(sodium ion export across plasma membrane)|go:"GO:0042383"(sarcolemma)|go:"GO:0046034"(ATP metabolic process)|go:"GO:0046982"(protein heterodimerization activity)|interpro:IPR000402(ATPase, P-type cation exchange, beta subunit)|interpro:IPR015565(Sodium/Potassium-Dependent ATPase Beta-1 Subunit)|interpro:IPR038702|mint:P07340|reactome:R-RNO-210991|reactome:R-RNO-5578775|reactome:R-RNO-936837|go:"GO:1990573"(potassium ion import across plasma membrane)	-	-	-	figure legend:ST1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10116(rat-brain-cerebellum)|taxid:10116(Rattus norvegicus)	-	2020/10/30	2020/10/30	rogid:DtE+ZXAZKdCMvUW5K+jXQ5bH07M10116	rogid:gJJ7PU6Tz3znT4wWy7GIPSV/x9w10116	rigid:OaXQ9NA25fwCWxejPU3Ao9q5j/E	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q5XIE8	uniprotkb:P49432	intact:EBI-15348306|ensembl:ENSRNOP00000023037	intact:EBI-917663|uniprotkb:Q6AY95|ensembl:ENSRNOP00000010545	psi-mi:itm2b_rat(display_long)|uniprotkb:Itm2b(gene name)|psi-mi:Itm2b(display_short)|uniprotkb:Immature BRI2(gene name synonym)|uniprotkb:Transmembrane protein BRI(gene name synonym)	psi-mi:odpb_rat(display_long)|uniprotkb:Pdhb(gene name)|psi-mi:Pdhb(display_short)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Martins et al. (2018)	imex:IM-28469|pubmed:29476059	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26438079|imex:IM-28469-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSRNOG00000016271(gene)|ensembl:ENSRNOT00000023037(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001540"(amyloid-beta binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0010008"(endosome membrane)|go:"GO:0030660"(Golgi-associated vesicle membrane)|go:"GO:0031301"(integral component of organelle membrane)|go:"GO:0042985"(negative regulation of amyloid precursor protein biosynthetic process)|interpro:IPR007084(BRICHOS)|interpro:IPR040145|mint:Q5XIE8|refseq:NP_001006964.1|rgd:620727	rgd:1359146|refseq:NP_001007621.1|ensembl:ENSRNOG00000007895(gene)|ensembl:ENSRNOT00000010545(transcript)|go:"GO:0004739"("pyruvate dehydrogenase (acetyl-transferring) activity")|go:"GO:0005739"(mitochondrion)|go:"GO:0005967"(mitochondrial pyruvate dehydrogenase complex)|go:"GO:0006006"(glucose metabolic process)|go:"GO:0006086"(acetyl-CoA biosynthetic process from pyruvate)|go:"GO:0006099"(tricarboxylic acid cycle)|go:"GO:0045254"(pyruvate dehydrogenase complex)|interpro:IPR005475(Transketolase, central region)|interpro:IPR009014(Transketolase, C-terminal/Pyruvate-ferredoxin oxidoreductase, domain II)|interpro:IPR027110|interpro:IPR029061|interpro:IPR033248|mint:P49432|reactome:R-RNO-204174|reactome:R-RNO-389661|reactome:R-RNO-5362517|reactome:R-RNO-70268|refseq:XP_006251816.1	-	-	-	figure legend:ST1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10116(rat-brain-cerebellum)|taxid:10116(Rattus norvegicus)	-	2020/10/30	2020/10/30	rogid:DtE+ZXAZKdCMvUW5K+jXQ5bH07M10116	rogid:IauZD1wmQ+/x/0WJZxx7kyX8FT410116	rigid:OaXQ9NA25fwCWxejPU3Ao9q5j/E	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q5XIE8	uniprotkb:Q66HF1	intact:EBI-15348306|ensembl:ENSRNOP00000023037	intact:EBI-21997221|ensembl:ENSRNOP00000015851	psi-mi:itm2b_rat(display_long)|uniprotkb:Itm2b(gene name)|psi-mi:Itm2b(display_short)|uniprotkb:Immature BRI2(gene name synonym)|uniprotkb:Transmembrane protein BRI(gene name synonym)	psi-mi:ndus1_rat(display_long)|uniprotkb:Ndufs1(gene name)|psi-mi:Ndufs1(display_short)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Martins et al. (2018)	imex:IM-28469|pubmed:29476059	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26438079|imex:IM-28469-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSRNOG00000016271(gene)|ensembl:ENSRNOT00000023037(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001540"(amyloid-beta binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0010008"(endosome membrane)|go:"GO:0030660"(Golgi-associated vesicle membrane)|go:"GO:0031301"(integral component of organelle membrane)|go:"GO:0042985"(negative regulation of amyloid precursor protein biosynthetic process)|interpro:IPR007084(BRICHOS)|interpro:IPR040145|mint:Q5XIE8|refseq:NP_001006964.1|rgd:620727	rgd:1359670|refseq:NP_001005550.1|ensembl:ENSRNOG00000011849(gene)|ensembl:ENSRNOT00000015852(transcript)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005747"(mitochondrial respiratory chain complex I)|go:"GO:0005758"(mitochondrial intermembrane space)|go:"GO:0006120"(mitochondrial electron transport, NADH to ubiquinone)|go:"GO:0008137"("NADH dehydrogenase (ubiquinone) activity")|go:"GO:0008637"(apoptotic mitochondrial changes)|go:"GO:0009055"(electron transfer activity)|go:"GO:0032981"(mitochondrial respiratory chain complex I assembly)|go:"GO:0045333"(cellular respiration)|go:"GO:0046034"(ATP metabolic process)|go:"GO:0046872"(metal ion binding)|go:"GO:0051537"(2 iron, 2 sulfur cluster binding)|go:"GO:0051539"(4 iron, 4 sulfur cluster binding)|go:"GO:0051881"(regulation of mitochondrial membrane potential)|go:"GO:0072593"(reactive oxygen species metabolic process)|interpro:IPR000283(NADH dehydrogenase 75 kDa subunit, conserved site)|interpro:IPR001041(Ferredoxin)|interpro:IPR006656(Molybdopterin oxidoreductase)|interpro:IPR006963(Molybdopterin oxidoreductase Fe4S4 region)|interpro:IPR010228(NADH-quinone oxidoreductase, chain G)|interpro:IPR015405(NADH-quinone oxidoreductase, chain G, C-terminal)|interpro:IPR019574|interpro:IPR036010|mint:Q66HF1|reactome:R-RNO-611105|reactome:R-RNO-6799198	-	-	-	figure legend:ST1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10116(rat-brain-cerebellum)|taxid:10116(Rattus norvegicus)	-	2020/10/30	2020/10/30	rogid:DtE+ZXAZKdCMvUW5K+jXQ5bH07M10116	rogid:rBq5pYwfc7co6OKLTc8OUF4jX1g10116	rigid:OaXQ9NA25fwCWxejPU3Ao9q5j/E	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q5XIE8	uniprotkb:P97700	intact:EBI-15348306|ensembl:ENSRNOP00000023037	intact:EBI-918109	psi-mi:itm2b_rat(display_long)|uniprotkb:Itm2b(gene name)|psi-mi:Itm2b(display_short)|uniprotkb:Immature BRI2(gene name synonym)|uniprotkb:Transmembrane protein BRI(gene name synonym)	psi-mi:m2om_rat(display_long)|uniprotkb:Solute carrier family 25 member 11(gene name synonym)|uniprotkb:Slc25a11(gene name)|psi-mi:Slc25a11(display_short)|uniprotkb:Slc20a4(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Martins et al. (2018)	imex:IM-28469|pubmed:29476059	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26438079|imex:IM-28469-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSRNOG00000016271(gene)|ensembl:ENSRNOT00000023037(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001540"(amyloid-beta binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0010008"(endosome membrane)|go:"GO:0030660"(Golgi-associated vesicle membrane)|go:"GO:0031301"(integral component of organelle membrane)|go:"GO:0042985"(negative regulation of amyloid precursor protein biosynthetic process)|interpro:IPR007084(BRICHOS)|interpro:IPR040145|mint:Q5XIE8|refseq:NP_001006964.1|rgd:620727	rgd:708476|refseq:NP_071793.1|interpro:IPR018108|interpro:IPR023395|mint:P97700|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0008272"(sulfate transport)|go:"GO:0015116"(sulfate transmembrane transporter activity)|go:"GO:0015117"(thiosulfate transmembrane transporter activity)|go:"GO:0015131"(oxaloacetate transmembrane transporter activity)|go:"GO:0015139"(alpha-ketoglutarate transmembrane transporter activity)|go:"GO:0015140"(malate transmembrane transporter activity)|go:"GO:0015141"(succinate transmembrane transporter activity)|go:"GO:0015297"(antiporter activity)|go:"GO:0015709"(thiosulfate transport)|go:"GO:0015729"(oxaloacetate transport)|go:"GO:0016021"(integral component of membrane)|go:"GO:0035435"(phosphate ion transmembrane transport)|go:"GO:0071422"(succinate transmembrane transport)|go:"GO:0071423"(malate transmembrane transport)|reactome:R-RNO-70263	-	-	-	figure legend:ST1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10116(rat-brain-cerebellum)|taxid:10116(Rattus norvegicus)	-	2020/10/30	2020/10/30	rogid:DtE+ZXAZKdCMvUW5K+jXQ5bH07M10116	rogid:CwkgqsG6PQ93hzzwLedusjml4do10116	rigid:OaXQ9NA25fwCWxejPU3Ao9q5j/E	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q5XIE8	uniprotkb:P04897	intact:EBI-15348306|ensembl:ENSRNOP00000023037	intact:EBI-915875|ensembl:ENSRNOP00000022550	psi-mi:itm2b_rat(display_long)|uniprotkb:Itm2b(gene name)|psi-mi:Itm2b(display_short)|uniprotkb:Immature BRI2(gene name synonym)|uniprotkb:Transmembrane protein BRI(gene name synonym)	psi-mi:gnai2_rat(display_long)|uniprotkb:Adenylate cyclase-inhibiting G alpha protein(gene name synonym)|uniprotkb:Gnai2(gene name)|psi-mi:Gnai2(display_short)|uniprotkb:Gnai-2(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Martins et al. (2018)	imex:IM-28469|pubmed:29476059	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26438079|imex:IM-28469-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSRNOG00000016271(gene)|ensembl:ENSRNOT00000023037(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001540"(amyloid-beta binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0010008"(endosome membrane)|go:"GO:0030660"(Golgi-associated vesicle membrane)|go:"GO:0031301"(integral component of organelle membrane)|go:"GO:0042985"(negative regulation of amyloid precursor protein biosynthetic process)|interpro:IPR007084(BRICHOS)|interpro:IPR040145|mint:Q5XIE8|refseq:NP_001006964.1|rgd:620727	rgd:620243|refseq:NP_112297.1|refseq:XP_006243920.1|dip:DIP-607N|ensembl:ENSRNOG00000016592(gene)|ensembl:ENSRNOT00000022550(transcript)|go:"GO:0001664"(G protein-coupled receptor binding)|go:"GO:0001973"(G protein-coupled adenosine receptor signaling pathway)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005834"(heterotrimeric G-protein complex)|go:"GO:0005886"(plasma membrane)|go:"GO:0007049"(cell cycle)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0007188"(adenylate cyclase-modulating G protein-coupled receptor signaling pathway)|go:"GO:0007189"(adenylate cyclase-activating G protein-coupled receptor signaling pathway)|go:"GO:0007193"(adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway)|go:"GO:0007213"(G protein-coupled acetylcholine receptor signaling pathway)|go:"GO:0007214"(gamma-aminobutyric acid signaling pathway)|go:"GO:0008283"(cell population proliferation)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0016020"(membrane)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0030425"(dendrite)|go:"GO:0030496"(midbody)|go:"GO:0031683"(G-protein beta/gamma-subunit complex binding)|go:"GO:0032930"(positive regulation of superoxide anion generation)|go:"GO:0033864"("positive regulation of NAD(P)H oxidase activity")|go:"GO:0035810"(positive regulation of urine volume)|go:"GO:0035815"(positive regulation of renal sodium excretion)|go:"GO:0044297"(cell body)|go:"GO:0045121"(membrane raft)|go:"GO:0045202"(synapse)|go:"GO:0045955"(negative regulation of calcium ion-dependent exocytosis)|go:"GO:0046628"(positive regulation of insulin receptor signaling pathway)|go:"GO:0046872"(metal ion binding)|go:"GO:0050805"(negative regulation of synaptic transmission)|go:"GO:0051301"(cell division)|go:"GO:0051924"(regulation of calcium ion transport)|go:"GO:0070374"(positive regulation of ERK1 and ERK2 cascade)|go:"GO:0140199"(negative regulation of adenylate cyclase-activating adrenergic receptor signaling pathway involved in heart process)|go:"GO:1903614"(negative regulation of protein tyrosine phosphatase activity)|go:"GO:1904707"(positive regulation of vascular associated smooth muscle cell proliferation)|go:"GO:2000179"(positive regulation of neural precursor cell proliferation)|go:"GO:2001234"(negative regulation of apoptotic signaling pathway)|interpro:IPR001019("Guanine nucleotide binding protein (G-protein), alpha subunit")|interpro:IPR001408(G-protein alpha subunit, group I)|interpro:IPR011025(G protein alpha subunit, helical insertion)|interpro:IPR027417|mint:P04897|reactome:R-RNO-170670|reactome:R-RNO-392170|reactome:R-RNO-400042|reactome:R-RNO-418594|reactome:R-RNO-9009391	-	-	-	figure legend:ST1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10116(rat-brain-cerebellum)|taxid:10116(Rattus norvegicus)	-	2020/10/30	2020/10/30	rogid:DtE+ZXAZKdCMvUW5K+jXQ5bH07M10116	rogid:TXAwhCxZGiWn/waR1XaK92nByh410116	rigid:OaXQ9NA25fwCWxejPU3Ao9q5j/E	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q5XIE8	uniprotkb:Q68FX0	intact:EBI-15348306|ensembl:ENSRNOP00000023037	intact:EBI-1216909|ensembl:ENSRNOP00000009681	psi-mi:itm2b_rat(display_long)|uniprotkb:Itm2b(gene name)|psi-mi:Itm2b(display_short)|uniprotkb:Immature BRI2(gene name synonym)|uniprotkb:Transmembrane protein BRI(gene name synonym)	psi-mi:idh3b_rat(display_long)|uniprotkb:Idh3B(gene name)|psi-mi:Idh3B(display_short)|uniprotkb:Isocitric dehydrogenase subunit beta(gene name synonym)|uniprotkb:"NAD(+)-specific ICDH subunit beta"(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Martins et al. (2018)	imex:IM-28469|pubmed:29476059	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26438079|imex:IM-28469-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSRNOG00000016271(gene)|ensembl:ENSRNOT00000023037(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001540"(amyloid-beta binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0010008"(endosome membrane)|go:"GO:0030660"(Golgi-associated vesicle membrane)|go:"GO:0031301"(integral component of organelle membrane)|go:"GO:0042985"(negative regulation of amyloid precursor protein biosynthetic process)|interpro:IPR007084(BRICHOS)|interpro:IPR040145|mint:Q5XIE8|refseq:NP_001006964.1|rgd:620727	rgd:621881|refseq:NP_446033.1|go:"GO:0006099"(tricarboxylic acid cycle)|go:"GO:0006102"(isocitrate metabolic process)|go:"GO:0006103"(2-oxoglutarate metabolic process)|go:"GO:0006734"(NADH metabolic process)|go:"GO:0051287"(NAD binding)|interpro:IPR004434(Isocitrate dehydrogenase NAD-dependent, mitochondrial)|interpro:IPR019818|interpro:IPR024084|mint:Q68FX0|reactome:R-RNO-71403|ensembl:ENSRNOG00000007316(gene)|ensembl:ENSRNOT00000009681(transcript)|go:"GO:0000287"(magnesium ion binding)|go:"GO:0004449"("isocitrate dehydrogenase (NAD+) activity")|go:"GO:0005739"(mitochondrion)|go:"GO:0005962"("mitochondrial isocitrate dehydrogenase complex (NAD+)")	-	-	-	figure legend:ST1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10116(rat-brain-cerebellum)|taxid:10116(Rattus norvegicus)	-	2020/10/30	2020/10/30	rogid:DtE+ZXAZKdCMvUW5K+jXQ5bH07M10116	rogid:DAPnk1qn2Ksoy7kcoPBWiiBcwTQ10116	rigid:OaXQ9NA25fwCWxejPU3Ao9q5j/E	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q5XIE8	uniprotkb:P31647	intact:EBI-15348306|ensembl:ENSRNOP00000023037	intact:EBI-26437303|ensembl:ENSRNOP00000008342	psi-mi:itm2b_rat(display_long)|uniprotkb:Itm2b(gene name)|psi-mi:Itm2b(display_short)|uniprotkb:Immature BRI2(gene name synonym)|uniprotkb:Transmembrane protein BRI(gene name synonym)	psi-mi:s6a11_rat(display_long)|uniprotkb:Slc6a11(gene name)|psi-mi:Slc6a11(display_short)|uniprotkb:Gabt3(gene name synonym)|uniprotkb:Gat-3(gene name synonym)|uniprotkb:Gat-b(gene name synonym)|uniprotkb:Solute carrier family 6 member 11(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Martins et al. (2018)	imex:IM-28469|pubmed:29476059	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26438079|imex:IM-28469-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSRNOG00000016271(gene)|ensembl:ENSRNOT00000023037(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001540"(amyloid-beta binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0010008"(endosome membrane)|go:"GO:0030660"(Golgi-associated vesicle membrane)|go:"GO:0031301"(integral component of organelle membrane)|go:"GO:0042985"(negative regulation of amyloid precursor protein biosynthetic process)|interpro:IPR007084(BRICHOS)|interpro:IPR040145|mint:Q5XIE8|refseq:NP_001006964.1|rgd:620727	ensembl:ENSRNOG00000005697(gene)|ensembl:ENSRNOT00000008342(transcript)|go:"GO:0001504"(neurotransmitter uptake)|go:"GO:0005332"("gamma-aminobutyric acid:sodium symporter activity")|go:"GO:0005737"(cytoplasm)|go:"GO:0099055"(integral component of postsynaptic membrane)|go:"GO:0099056"(integral component of presynaptic membrane)|interpro:IPR000175("Sodium:neurotransmitter symporter")|interpro:IPR002982("Sodium:neurotransmitter symporter, GABA, GAT-3")|interpro:IPR037272|mint:P31647|reactome:R-RNO-442660|reactome:R-RNO-71288|reactome:R-RNO-888593|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006836"(neurotransmitter transport)|go:"GO:0007420"(brain development)|go:"GO:0008028"(monocarboxylic acid transmembrane transporter activity)|go:"GO:0015718"(monocarboxylic acid transport)|go:"GO:0016020"(membrane)|go:"GO:0035725"(sodium ion transmembrane transport)|go:"GO:0042165"(neurotransmitter binding)|go:"GO:0042493"|go:"GO:0042995"(cell projection)|go:"GO:0043005"(neuron projection)|go:"GO:0045202"(synapse)|go:"GO:0098810"(neurotransmitter reuptake)|go:"GO:0098982"(GABA-ergic synapse)|refseq:NP_077348.1|rgd:628737	-	-	-	figure legend:ST1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10116(rat-brain-cerebellum)|taxid:10116(Rattus norvegicus)	-	2020/10/30	2020/10/30	rogid:DtE+ZXAZKdCMvUW5K+jXQ5bH07M10116	rogid:9i3Xw3eX7laWYPUzbkNHsaO3kws10116	rigid:OaXQ9NA25fwCWxejPU3Ao9q5j/E	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q5XIE8	uniprotkb:Q9QX74	intact:EBI-15348306|ensembl:ENSRNOP00000023037	intact:EBI-397902|ensembl:ENSRNOP00000067841|uniprotkb:Q9WUW0|uniprotkb:O70470|uniprotkb:Q6WB19|uniprotkb:Q9QX93|uniprotkb:Q9QZZ9|uniprotkb:Q9WUV9|uniprotkb:Q9WV46	psi-mi:itm2b_rat(display_long)|uniprotkb:Itm2b(gene name)|psi-mi:Itm2b(display_short)|uniprotkb:Immature BRI2(gene name synonym)|uniprotkb:Transmembrane protein BRI(gene name synonym)	psi-mi:shan2_rat(display_long)|uniprotkb:Cortactin-binding protein 1(gene name synonym)|uniprotkb:Proline-rich synapse-associated protein 1(gene name synonym)|uniprotkb:GKAP/SAPAP-interacting protein(gene name synonym)|uniprotkb:SPANK-3(gene name synonym)|uniprotkb:Shank2(gene name)|psi-mi:Shank2(display_short)|uniprotkb:Cortbp1(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Martins et al. (2018)	imex:IM-28469|pubmed:29476059	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26438079|imex:IM-28469-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSRNOG00000016271(gene)|ensembl:ENSRNOT00000023037(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001540"(amyloid-beta binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0010008"(endosome membrane)|go:"GO:0030660"(Golgi-associated vesicle membrane)|go:"GO:0031301"(integral component of organelle membrane)|go:"GO:0042985"(negative regulation of amyloid precursor protein biosynthetic process)|interpro:IPR007084(BRICHOS)|interpro:IPR040145|mint:Q5XIE8|refseq:NP_001006964.1|rgd:620727	rgd:628772|refseq:NP_001004133.1|refseq:NP_597684.1|refseq:NP_597685.1|refseq:NP_958738.1|ensembl:ENSRNOG00000050206(gene)|ensembl:ENSRNOT00000071741(transcript)|go:"GO:0001750"(photoreceptor outer segment)|go:"GO:0001917"(photoreceptor inner segment)|go:"GO:0005883"(neurofilament)|go:"GO:0005886"(plasma membrane)|go:"GO:0007416"(synapse assembly)|go:"GO:0007420"(brain development)|go:"GO:0007584"(response to nutrient)|go:"GO:0007612"(learning)|go:"GO:0007613"(memory)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0008328"(ionotropic glutamate receptor complex)|go:"GO:0014069"(postsynaptic density)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0030160"(synaptic receptor adaptor activity)|go:"GO:0030426"(growth cone)|go:"GO:0030534"(adult behavior)|go:"GO:0031526"(brush border membrane)|go:"GO:0032279"(asymmetric synapse)|go:"GO:0035176"(social behavior)|go:"GO:0035255"(ionotropic glutamate receptor binding)|go:"GO:0035331"(negative regulation of hippo signaling)|go:"GO:0035640"(exploration behavior)|go:"GO:0043005"(neuron projection)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043197"(dendritic spine)|go:"GO:0048786"(presynaptic active zone)|go:"GO:0050807"(regulation of synapse organization)|go:"GO:0051968"(positive regulation of synaptic transmission, glutamatergic)|go:"GO:0060170"(ciliary membrane)|go:"GO:0060291"(long-term synaptic potentiation)|go:"GO:0060292"(long-term synaptic depression)|go:"GO:0071625"(vocalization behavior)|go:"GO:0098686"(hippocampal mossy fiber to CA3 synapse)|go:"GO:0098919"(structural constituent of postsynaptic density)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099562"(maintenance of postsynaptic density structure)|interpro:IPR001452(Src homology-3)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR001660(Sterile alpha motif SAM)|interpro:IPR013761(Sterile alpha motif-type)|interpro:IPR036028|interpro:IPR036034|interpro:IPR041489|mint:Q9QX74|rcsb pdb:6CPJ|reactome:R-RNO-6794361|refseq:XP_017444213.1	-	-	-	figure legend:ST1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10116(rat-brain-cerebellum)|taxid:10116(Rattus norvegicus)	-	2020/10/30	2020/10/30	rogid:DtE+ZXAZKdCMvUW5K+jXQ5bH07M10116	rogid:rSjkRiT94GNUbX9ul/buccWjgcM10116	rigid:OaXQ9NA25fwCWxejPU3Ao9q5j/E	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q5XIE8	uniprotkb:Q9WV48	intact:EBI-15348306|ensembl:ENSRNOP00000023037	intact:EBI-80909|uniprotkb:Q9QZZ8|uniprotkb:Q9WU13|uniprotkb:Q9WUE8|ensembl:ENSRNOP00000026100	psi-mi:itm2b_rat(display_long)|uniprotkb:Itm2b(gene name)|psi-mi:Itm2b(display_short)|uniprotkb:Immature BRI2(gene name synonym)|uniprotkb:Transmembrane protein BRI(gene name synonym)	psi-mi:shan1_rat(display_long)|uniprotkb:Shank1(gene name)|psi-mi:Shank1(display_short)|uniprotkb:GKAP/SAPAP-interacting protein(gene name synonym)|uniprotkb:Synamon(gene name synonym)|uniprotkb:Somatostatin receptor-interacting protein(gene name synonym)|uniprotkb:SPANK-1(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Martins et al. (2018)	imex:IM-28469|pubmed:29476059	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26438079|imex:IM-28469-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSRNOG00000016271(gene)|ensembl:ENSRNOT00000023037(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001540"(amyloid-beta binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0010008"(endosome membrane)|go:"GO:0030660"(Golgi-associated vesicle membrane)|go:"GO:0031301"(integral component of organelle membrane)|go:"GO:0042985"(negative regulation of amyloid precursor protein biosynthetic process)|interpro:IPR007084(BRICHOS)|interpro:IPR040145|mint:Q5XIE8|refseq:NP_001006964.1|rgd:620727	rgd:621011|refseq:NP_113939.2|ensembl:ENSRNOG00000019207(gene)|ensembl:ENSRNOT00000026100(transcript)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0007616"(long-term memory)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008306"(associative learning)|go:"GO:0008328"(ionotropic glutamate receptor complex)|go:"GO:0014069"(postsynaptic density)|go:"GO:0016020"(membrane)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0030159"(signaling receptor complex adaptor activity)|go:"GO:0030160"(synaptic receptor adaptor activity)|go:"GO:0030425"(dendrite)|go:"GO:0030534"(adult behavior)|go:"GO:0032232"(negative regulation of actin filament bundle assembly)|go:"GO:0035176"(social behavior)|go:"GO:0035255"(ionotropic glutamate receptor binding)|go:"GO:0035418"(protein localization to synapse)|go:"GO:0042048"(olfactory behavior)|go:"GO:0042802"(identical protein binding)|go:"GO:0043005"(neuron projection)|go:"GO:0031877"(somatostatin receptor binding)|go:"GO:0043197"(dendritic spine)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045202"(synapse)|go:"GO:0045211"(postsynaptic membrane)|go:"GO:0046959"(habituation)|go:"GO:0050885"(neuromuscular process controlling balance)|go:"GO:0050894"(determination of affect)|go:"GO:0060013"(righting reflex)|go:"GO:0060074"(synapse maturation)|go:"GO:0060076"(excitatory synapse)|go:"GO:0060997"(dendritic spine morphogenesis)|go:"GO:0060999"(positive regulation of dendritic spine development)|go:"GO:0065003"(protein-containing complex assembly)|go:"GO:0071532"(ankyrin repeat binding)|go:"GO:0071625"(vocalization behavior)|go:"GO:0097110"(scaffold protein binding)|go:"GO:0098685"(Schaffer collateral - CA1 synapse)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099173"(postsynapse organization)|go:"GO:2000311"(regulation of AMPA receptor activity)|go:"GO:2000463"(positive regulation of excitatory postsynaptic potential)|interpro:IPR001452(Src homology-3)|interpro:IPR020683|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR036028|interpro:IPR036034|interpro:IPR036770|interpro:IPR041489|mint:Q9WV48|rcsb pdb:1Q3O|rcsb pdb:1Q3P|rcsb pdb:3L4F|rcsb pdb:3QJM|interpro:IPR001660(Sterile alpha motif SAM)|rcsb pdb:3QJN|rcsb pdb:7A9B|interpro:IPR002110(Ankyrin)|reactome:R-RNO-6794361|interpro:IPR013761(Sterile alpha motif-type)|refseq:XP_017445247.1|refseq:XP_017445248.1|refseq:XP_017445249.1|refseq:XP_017445250.1	-	-	-	figure legend:ST1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10116(rat-brain-cerebellum)|taxid:10116(Rattus norvegicus)	-	2020/10/30	2020/10/30	rogid:DtE+ZXAZKdCMvUW5K+jXQ5bH07M10116	rogid:EHavC08yPAiG9wbnxLHyWaRZj4g10116	rigid:OaXQ9NA25fwCWxejPU3Ao9q5j/E	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q5XIE8	uniprotkb:Q64578	intact:EBI-15348306|ensembl:ENSRNOP00000023037	intact:EBI-26437245	psi-mi:itm2b_rat(display_long)|uniprotkb:Itm2b(gene name)|psi-mi:Itm2b(display_short)|uniprotkb:Immature BRI2(gene name synonym)|uniprotkb:Transmembrane protein BRI(gene name synonym)	psi-mi:at2a1_rat(display_long)|uniprotkb:Atp2a1(gene name)|psi-mi:Atp2a1(display_short)|uniprotkb:Calcium pump 1(gene name synonym)|uniprotkb:Calcium-transporting ATPase sarcoplasmic reticulum type, fast twitch skeletal muscle isoform(gene name synonym)|uniprotkb:"Endoplasmic reticulum class 1/2 Ca(2+) ATPase"(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Martins et al. (2018)	imex:IM-28469|pubmed:29476059	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26438079|imex:IM-28469-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSRNOG00000016271(gene)|ensembl:ENSRNOT00000023037(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001540"(amyloid-beta binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0010008"(endosome membrane)|go:"GO:0030660"(Golgi-associated vesicle membrane)|go:"GO:0031301"(integral component of organelle membrane)|go:"GO:0042985"(negative regulation of amyloid precursor protein biosynthetic process)|interpro:IPR007084(BRICHOS)|interpro:IPR040145|mint:Q5XIE8|refseq:NP_001006964.1|rgd:620727	go:"GO:0005338"(nucleotide-sugar transmembrane transporter activity)|go:"GO:0005388"(P-type calcium transporter activity)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005739"(mitochondrion)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005793"(endoplasmic reticulum-Golgi intermediate compartment)|go:"GO:0006816"(calcium ion transport)|go:"GO:0006874"(cellular calcium ion homeostasis)|go:"GO:0006937"(regulation of muscle contraction)|go:"GO:0006942"(regulation of striated muscle contraction)|go:"GO:0008553"(P-type proton-exporting transporter activity)|go:"GO:0008637"(apoptotic mitochondrial changes)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016529"(sarcoplasmic reticulum)|go:"GO:0030899"(calcium-dependent ATPase activity)|go:"GO:0031448"(positive regulation of fast-twitch skeletal muscle fiber contraction)|go:"GO:0031673"(H zone)|go:"GO:0031674"(I band)|go:"GO:0032470"(positive regulation of endoplasmic reticulum calcium ion concentration)|go:"GO:0032471"(negative regulation of endoplasmic reticulum calcium ion concentration)|go:"GO:0034976"(response to endoplasmic reticulum stress)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0043434"(response to peptide hormone)|go:"GO:0045988"(negative regulation of striated muscle contraction)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051561"(positive regulation of mitochondrial calcium ion concentration)|go:"GO:0051659"(maintenance of mitochondrion location)|go:"GO:0070059"(intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress)|go:"GO:0070296"(sarcoplasmic reticulum calcium ion transport)|go:"GO:0070509"(calcium ion import)|go:"GO:0070588"(calcium ion transmembrane transport)|go:"GO:0090076"(relaxation of skeletal muscle)|go:"GO:0106134"(positive regulation of cardiac muscle cell contraction)|go:"GO:1901896"(positive regulation of ATPase-coupled calcium transmembrane transporter activity)|go:"GO:1902082"(positive regulation of calcium ion import into sarcoplasmic reticulum)|go:"GO:1990036"(calcium ion import into sarcoplasmic reticulum)|go:"GO:0033017"(sarcoplasmic reticulum membrane)|mint:Q64578|refseq:NP_478120.1|interpro:IPR006068(ATPase, P-type cation-transporter, C-terminal)|interpro:IPR004014(ATPase, P-type cation-transporter, N-terminal)|interpro:IPR023299|interpro:IPR018303|interpro:IPR023298|interpro:IPR008250(E1-E2 ATPase-associated region)|interpro:IPR036412|interpro:IPR023214|interpro:IPR005782(Calcium ATPase)|interpro:IPR001757(ATPase, P-type, K/Mg/Cd/Cu/Zn/Na/Ca/Na/H-transporter)|rgd:621293|interpro:IPR044492	-	-	-	figure legend:ST1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10116(rat-brain-cerebellum)|taxid:10116(Rattus norvegicus)	-	2020/10/30	2020/10/30	rogid:DtE+ZXAZKdCMvUW5K+jXQ5bH07M10116	rogid:QeoX1KkHMSA+GNGUBG0IGxUfDyM10116	rigid:OaXQ9NA25fwCWxejPU3Ao9q5j/E	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q5XIE8	uniprotkb:P26284	intact:EBI-15348306|ensembl:ENSRNOP00000023037	intact:EBI-1163773	psi-mi:itm2b_rat(display_long)|uniprotkb:Itm2b(gene name)|psi-mi:Itm2b(display_short)|uniprotkb:Immature BRI2(gene name synonym)|uniprotkb:Transmembrane protein BRI(gene name synonym)	psi-mi:odpa_rat(display_long)|uniprotkb:PDHE1-A type I(gene name synonym)|uniprotkb:Pdha1(gene name)|psi-mi:Pdha1(display_short)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Martins et al. (2018)	imex:IM-28469|pubmed:29476059	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26438079|imex:IM-28469-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSRNOG00000016271(gene)|ensembl:ENSRNOT00000023037(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001540"(amyloid-beta binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0010008"(endosome membrane)|go:"GO:0030660"(Golgi-associated vesicle membrane)|go:"GO:0031301"(integral component of organelle membrane)|go:"GO:0042985"(negative regulation of amyloid precursor protein biosynthetic process)|interpro:IPR007084(BRICHOS)|interpro:IPR040145|mint:Q5XIE8|refseq:NP_001006964.1|rgd:620727	interpro:IPR001017(Dehydrogenase, E1 component)|interpro:IPR017597("Pyruvate dehydrogenase (acetyl-transferring) E1 component, alpha subunit, subgroup y")|rgd:3286|go:"GO:0006006"(glucose metabolic process)|go:"GO:0006086"(acetyl-CoA biosynthetic process from pyruvate)|go:"GO:0006099"(tricarboxylic acid cycle)|go:"GO:0034604"("pyruvate dehydrogenase (NAD+) activity")|go:"GO:0045254"(pyruvate dehydrogenase complex)|go:"GO:0061732"(mitochondrial acetyl-CoA biosynthetic process from pyruvate)|reactome:R-RNO-204174|reactome:R-RNO-389661|reactome:R-RNO-5362517|reactome:R-RNO-70268|go:"GO:0004738"(pyruvate dehydrogenase activity)|go:"GO:0004739"("pyruvate dehydrogenase (acetyl-transferring) activity")|go:"GO:0005739"(mitochondrion)|go:"GO:0005967"(mitochondrial pyruvate dehydrogenase complex)|interpro:IPR029061|mint:P26284	-	-	-	figure legend:ST1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10116(rat-brain-cerebellum)|taxid:10116(Rattus norvegicus)	-	2020/10/30	2020/10/30	rogid:DtE+ZXAZKdCMvUW5K+jXQ5bH07M10116	rogid:ZS2XIIvPJLzbaoUBw21HHJw6gcw10116	rigid:OaXQ9NA25fwCWxejPU3Ao9q5j/E	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q5XIE8	uniprotkb:A7VJC2	intact:EBI-15348306|ensembl:ENSRNOP00000023037	intact:EBI-16220125|uniprotkb:A7VJC1|uniprotkb:A7VJC3|uniprotkb:A7VJC4	psi-mi:itm2b_rat(display_long)|uniprotkb:Itm2b(gene name)|psi-mi:Itm2b(display_short)|uniprotkb:Immature BRI2(gene name synonym)|uniprotkb:Transmembrane protein BRI(gene name synonym)	psi-mi:roa2_rat(display_long)|uniprotkb:Hnrnpa2b1(gene name)|psi-mi:Hnrnpa2b1(display_short)|uniprotkb:Hnrnp(gene name synonym)|uniprotkb:Hnrpa2b1(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Martins et al. (2018)	imex:IM-28469|pubmed:29476059	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26438079|imex:IM-28469-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSRNOG00000016271(gene)|ensembl:ENSRNOT00000023037(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001540"(amyloid-beta binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0010008"(endosome membrane)|go:"GO:0030660"(Golgi-associated vesicle membrane)|go:"GO:0031301"(integral component of organelle membrane)|go:"GO:0042985"(negative regulation of amyloid precursor protein biosynthetic process)|interpro:IPR007084(BRICHOS)|interpro:IPR040145|mint:Q5XIE8|refseq:NP_001006964.1|rgd:620727	go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0000785"(chromatin)|go:"GO:0001069"(regulatory region RNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0003730"(mRNA 3'-UTR binding)|go:"GO:0005634"(nucleus)|go:"GO:0005681"(spliceosomal complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0006397"(mRNA processing)|go:"GO:0006406"(mRNA export from nucleus)|go:"GO:0008584"(male gonad development)|go:"GO:0015030"(Cajal body)|go:"GO:0016233"(telomere capping)|go:"GO:0016363"(nuclear matrix)|go:"GO:0030324"(lung development)|go:"GO:0031053"(primary miRNA processing)|go:"GO:0035198"(miRNA binding)|go:"GO:0043005"(neuron projection)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043047"(single-stranded telomeric DNA binding)|go:"GO:0043204"(perikaryon)|go:"GO:0044806"(G-quadruplex DNA unwinding)|go:"GO:0048025"(negative regulation of mRNA splicing, via spliceosome)|go:"GO:0048709"(oligodendrocyte differentiation)|go:"GO:0050658"(RNA transport)|go:"GO:0051385"(response to mineralocorticoid)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070182"(DNA polymerase binding)|go:"GO:0071013"(catalytic step 2 spliceosome)|go:"GO:0071598"(neuronal ribonucleoprotein granule)|go:"GO:0097157"(pre-mRNA intronic binding)|go:"GO:0098505"(G-rich strand telomeric DNA binding)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099524"(postsynaptic cytosol)|go:"GO:1904358"(positive regulation of telomere maintenance via telomere lengthening)|go:"GO:1905663"(positive regulation of telomerase RNA reverse transcriptase activity)|go:"GO:1990247"(N6-methyladenosine-containing RNA binding)|go:"GO:1990428"(miRNA transport)|go:"GO:1990715"(mRNA CDS binding)|go:"GO:1990904"(ribonucleoprotein complex)|reactome:R-RNO-72163|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|mint:A7VJC2|rgd:1310403|refseq:NP_001098083.1|interpro:IPR034489|interpro:IPR034486|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR035979	-	-	-	figure legend:ST1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10116(rat-brain-cerebellum)|taxid:10116(Rattus norvegicus)	-	2020/10/30	2020/10/30	rogid:DtE+ZXAZKdCMvUW5K+jXQ5bH07M10116	rogid:RZtl5bMFuLp7kleC3+GUF5SQmEI10116	rigid:OaXQ9NA25fwCWxejPU3Ao9q5j/E	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q5XIE8	uniprotkb:P62762	intact:EBI-15348306|ensembl:ENSRNOP00000023037	intact:EBI-26437220|ensembl:ENSRNOP00000007609|uniprotkb:P28677|uniprotkb:P29103|uniprotkb:P42323|uniprotkb:Q9UM20	psi-mi:itm2b_rat(display_long)|uniprotkb:Itm2b(gene name)|psi-mi:Itm2b(display_short)|uniprotkb:Immature BRI2(gene name synonym)|uniprotkb:Transmembrane protein BRI(gene name synonym)	psi-mi:visl1_rat(display_long)|uniprotkb:Vsnl1(gene name)|psi-mi:Vsnl1(display_short)|uniprotkb:Visl1(gene name synonym)|uniprotkb:21 kDa CABP(gene name synonym)|uniprotkb:Neural visinin-like protein 1(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Martins et al. (2018)	imex:IM-28469|pubmed:29476059	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26438079|imex:IM-28469-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSRNOG00000016271(gene)|ensembl:ENSRNOT00000023037(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001540"(amyloid-beta binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0010008"(endosome membrane)|go:"GO:0030660"(Golgi-associated vesicle membrane)|go:"GO:0031301"(integral component of organelle membrane)|go:"GO:0042985"(negative regulation of amyloid precursor protein biosynthetic process)|interpro:IPR007084(BRICHOS)|interpro:IPR040145|mint:Q5XIE8|refseq:NP_001006964.1|rgd:620727	ensembl:ENSRNOT00000007609(transcript)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005829"(cytosol)|go:"GO:0007417"(central nervous system development)|go:"GO:0016020"(membrane)|go:"GO:0019722"(calcium-mediated signaling)|go:"GO:0035774"(positive regulation of insulin secretion involved in cellular response to glucose stimulus)|go:"GO:0045921"(positive regulation of exocytosis)|ensembl:ENSRNOG00000005345(gene)|go:"GO:0046676"(negative regulation of insulin secretion)|interpro:IPR002048(Calcium-binding EF-hand)|interpro:IPR011992(EF-Hand type)|interpro:IPR018247|interpro:IPR028846|interpro:IPR029533|mint:P62762|rgd:3966	-	-	-	figure legend:ST1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10116(rat-brain-cerebellum)|taxid:10116(Rattus norvegicus)	-	2020/10/30	2020/10/30	rogid:DtE+ZXAZKdCMvUW5K+jXQ5bH07M10116	rogid:k0Elc6uYX5rz8yUjSf+MGVGBzic10116	rigid:OaXQ9NA25fwCWxejPU3Ao9q5j/E	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q5XIE8	uniprotkb:P63045	intact:EBI-15348306|ensembl:ENSRNOP00000023037	intact:EBI-520880|uniprotkb:Q64357|intact:EBI-11701411|ensembl:ENSRNOP00000054114	psi-mi:itm2b_rat(display_long)|uniprotkb:Itm2b(gene name)|psi-mi:Itm2b(display_short)|uniprotkb:Immature BRI2(gene name synonym)|uniprotkb:Transmembrane protein BRI(gene name synonym)	psi-mi:vamp2_rat(display_long)|uniprotkb:Vamp2(gene name)|psi-mi:Vamp2(display_short)|uniprotkb:Syb2(gene name synonym)|uniprotkb:Synaptobrevin-2(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Martins et al. (2018)	imex:IM-28469|pubmed:29476059	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26438079|imex:IM-28469-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSRNOG00000016271(gene)|ensembl:ENSRNOT00000023037(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001540"(amyloid-beta binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0010008"(endosome membrane)|go:"GO:0030660"(Golgi-associated vesicle membrane)|go:"GO:0031301"(integral component of organelle membrane)|go:"GO:0042985"(negative regulation of amyloid precursor protein biosynthetic process)|interpro:IPR007084(BRICHOS)|interpro:IPR040145|mint:Q5XIE8|refseq:NP_001006964.1|rgd:620727	rgd:3949|refseq:NP_036795.1|dip:DIP-35503N|ensembl:ENSRNOG00000006989(gene)|ensembl:ENSRNOT00000057295(transcript)|go:"GO:0000149"(SNARE binding)|go:"GO:0000322"(storage vacuole)|go:"GO:0005484"(SNAP receptor activity)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005543"(phospholipid binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0005886"(plasma membrane)|go:"GO:0006906"(vesicle fusion)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0009749"(response to glucose)|go:"GO:0015031"(protein transport)|go:"GO:0016020"(membrane)|go:"GO:0016079"(synaptic vesicle exocytosis)|go:"GO:0016081"(synaptic vesicle docking)|go:"GO:0016192"(vesicle-mediated transport)|go:"GO:0017022"(myosin binding)|go:"GO:0017075"(syntaxin-1 binding)|go:"GO:0017156"(calcium-ion regulated exocytosis)|go:"GO:0017157"(regulation of exocytosis)|go:"GO:0019905"(syntaxin binding)|go:"GO:0030136"(clathrin-coated vesicle)|go:"GO:0030141"(secretory granule)|go:"GO:0030285"(integral component of synaptic vesicle membrane)|go:"GO:0030659"(cytoplasmic vesicle membrane)|go:"GO:0030672"(synaptic vesicle membrane)|go:"GO:0031201"(SNARE complex)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0031982"(vesicle)|go:"GO:0032869"(cellular response to insulin stimulus)|go:"GO:0035493"(SNARE complex assembly)|go:"GO:0042589"(zymogen granule membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0043001"(Golgi to plasma membrane protein transport)|go:"GO:0043005"(neuron projection)|go:"GO:0043195"(terminal bouton)|go:"GO:0043229"(intracellular organelle)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0043308"(eosinophil degranulation)|go:"GO:0044306"(neuron projection terminus)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045055"(regulated exocytosis)|go:"GO:0045202"(synapse)|go:"GO:0046879"(hormone secretion)|go:"GO:0048306"(calcium-dependent protein binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0048488"(synaptic vesicle endocytosis)|go:"GO:0060291"(long-term synaptic potentiation)|go:"GO:0060627"(regulation of vesicle-mediated transport)|go:"GO:0061025"(membrane fusion)|go:"GO:0065003"(protein-containing complex assembly)|go:"GO:0070032"(synaptobrevin 2-SNAP-25-syntaxin-1a-complexin I complex)|go:"GO:0070033"(synaptobrevin 2-SNAP-25-syntaxin-1a-complexin II complex)|go:"GO:0070044"(synaptobrevin 2-SNAP-25-syntaxin-1a complex)|go:"GO:0090316"(positive regulation of intracellular protein transport)|go:"GO:0098967"(exocytic insertion of neurotransmitter receptor to postsynaptic membrane)|go:"GO:1902259"(regulation of delayed rectifier potassium channel activity)|go:"GO:1903421"(regulation of synaptic vesicle recycling)|interpro:IPR001388(Synaptobrevin)|interpro:IPR016444(Synaptobrevin, metazoa/fungi)|interpro:IPR028717|interpro:IPR042855|mint:P63045|rcsb pdb:1KIL|rcsb pdb:1N7S|rcsb pdb:1SFC|rcsb pdb:2BU0|rcsb pdb:2KOG|rcsb pdb:2N1T|rcsb pdb:3HD7|rcsb pdb:3IPD|rcsb pdb:3J96|rcsb pdb:3J97|rcsb pdb:3J98|rcsb pdb:3J99|rcsb pdb:5CCG|rcsb pdb:5CCH|rcsb pdb:5CCI|rcsb pdb:5W5C|rcsb pdb:5W5D|rcsb pdb:6A30|rcsb pdb:6IP1|rcsb pdb:6MDM|rcsb pdb:6MDN|rcsb pdb:6MTI|rcsb pdb:6WVW|reactome:R-RNO-181429|reactome:R-RNO-181430|reactome:R-RNO-210500|reactome:R-RNO-212676|reactome:R-RNO-8856825|reactome:R-RNO-264642|reactome:R-RNO-432720|reactome:R-RNO-432722|reactome:R-RNO-449836|reactome:R-RNO-8856828|reactome:R-RNO-888590|reactome:R-RNO-9609523	-	-	-	figure legend:ST1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10116(rat-brain-cerebellum)|taxid:10116(Rattus norvegicus)	-	2020/10/30	2020/10/30	rogid:DtE+ZXAZKdCMvUW5K+jXQ5bH07M10116	rogid:7XvjYTyMU62KV/BKEItoUAtIL5010116	rigid:OaXQ9NA25fwCWxejPU3Ao9q5j/E	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q5XIE8	uniprotkb:Q63666	intact:EBI-15348306|ensembl:ENSRNOP00000023037	intact:EBI-2029956|uniprotkb:A6YSN3|uniprotkb:O09025|uniprotkb:Q56A22|uniprotkb:Q8CH14|ensembl:ENSRNOP00000025081	psi-mi:itm2b_rat(display_long)|uniprotkb:Itm2b(gene name)|psi-mi:Itm2b(display_short)|uniprotkb:Immature BRI2(gene name synonym)|uniprotkb:Transmembrane protein BRI(gene name synonym)	psi-mi:vamp1_rat(display_long)|uniprotkb:Vamp1(gene name)|psi-mi:Vamp1(display_short)|uniprotkb:Syb1(gene name synonym)|uniprotkb:Synaptobrevin-1(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Martins et al. (2018)	imex:IM-28469|pubmed:29476059	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26438079|imex:IM-28469-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSRNOG00000016271(gene)|ensembl:ENSRNOT00000023037(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001540"(amyloid-beta binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0010008"(endosome membrane)|go:"GO:0030660"(Golgi-associated vesicle membrane)|go:"GO:0031301"(integral component of organelle membrane)|go:"GO:0042985"(negative regulation of amyloid precursor protein biosynthetic process)|interpro:IPR007084(BRICHOS)|interpro:IPR040145|mint:Q5XIE8|refseq:NP_001006964.1|rgd:620727	rgd:3948|refseq:NP_037222.2|ensembl:ENSRNOG00000019219(gene)|ensembl:ENSRNOT00000025081(transcript)|go:"GO:0005484"(SNAP receptor activity)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005886"(plasma membrane)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006906"(vesicle fusion)|go:"GO:0016192"(vesicle-mediated transport)|go:"GO:0019905"(syntaxin binding)|go:"GO:0030285"(integral component of synaptic vesicle membrane)|go:"GO:0031201"(SNARE complex)|go:"GO:0035493"(SNARE complex assembly)|go:"GO:0035579"(specific granule membrane)|go:"GO:0043195"(terminal bouton)|go:"GO:0070821"(tertiary granule membrane)|go:"GO:0098793"(presynapse)|interpro:IPR001388(Synaptobrevin)|interpro:IPR016444(Synaptobrevin, metazoa/fungi)|interpro:IPR042855|mint:Q63666	-	-	-	figure legend:ST1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10116(rat-brain-cerebellum)|taxid:10116(Rattus norvegicus)	-	2020/10/30	2020/10/30	rogid:DtE+ZXAZKdCMvUW5K+jXQ5bH07M10116	rogid:XGwIWepyYnUkrB97k7IAoIbbipY10116	rigid:OaXQ9NA25fwCWxejPU3Ao9q5j/E	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q5XIE8	uniprotkb:Q9ERB4	intact:EBI-15348306|ensembl:ENSRNOP00000023037	intact:EBI-26437171|uniprotkb:O08592|uniprotkb:O88564|uniprotkb:Q9R1K4	psi-mi:itm2b_rat(display_long)|uniprotkb:Itm2b(gene name)|psi-mi:Itm2b(display_short)|uniprotkb:Immature BRI2(gene name synonym)|uniprotkb:Transmembrane protein BRI(gene name synonym)	psi-mi:cspg2_rat(display_long)|uniprotkb:Vcan(gene name)|psi-mi:Vcan(display_short)|uniprotkb:Cspg2(gene name synonym)|uniprotkb:Chondroitin sulfate proteoglycan core protein 2(gene name synonym)|uniprotkb:Glial hyaluronate-binding protein(gene name synonym)|uniprotkb:Large fibroblast proteoglycan(gene name synonym)|uniprotkb:PG-M(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Martins et al. (2018)	imex:IM-28469|pubmed:29476059	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26438079|imex:IM-28469-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSRNOG00000016271(gene)|ensembl:ENSRNOT00000023037(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001540"(amyloid-beta binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0010008"(endosome membrane)|go:"GO:0030660"(Golgi-associated vesicle membrane)|go:"GO:0031301"(integral component of organelle membrane)|go:"GO:0042985"(negative regulation of amyloid precursor protein biosynthetic process)|interpro:IPR007084(BRICHOS)|interpro:IPR040145|mint:Q5XIE8|refseq:NP_001006964.1|rgd:620727	reactome:R-RNO-2024101|reactome:R-RNO-3000178|reactome:R-RNO-381426|reactome:R-RNO-8957275|go:"GO:0001501"(skeletal system development)|go:"GO:0001657"(ureteric bud development)|go:"GO:0001750"(photoreceptor outer segment)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005540"(hyaluronic acid binding)|go:"GO:0005576"(extracellular region)|go:"GO:0007155"(cell adhesion)|go:"GO:0007417"(central nervous system development)|go:"GO:0007507"(heart development)|go:"GO:0009611"(response to wounding)|go:"GO:0009986"(cell surface)|go:"GO:0019903"(protein phosphatase binding)|go:"GO:0030169"(low-density lipoprotein particle binding)|go:"GO:0030246"(carbohydrate binding)|go:"GO:0031012"(extracellular matrix)|go:"GO:0031103"(axon regeneration)|go:"GO:0033165"(interphotoreceptor matrix)|go:"GO:0045202"(synapse)|go:"GO:0062023"(collagen-containing extracellular matrix)|go:"GO:0072534"(perineuronal net)|reactome:R-RNO-1971475|reactome:R-RNO-2022870|reactome:R-RNO-2022923|mint:Q9ERB4|refseq:NP_001164029.1|refseq:NP_001164030.1|refseq:NP_001164031.1|interpro:IPR001304(C-type lectin)|interpro:IPR016186(C-type lectin-like)|interpro:IPR018378|interpro:IPR033987|interpro:IPR016187(C-type lectin fold)|interpro:IPR001881(EGF-like calcium-binding)|interpro:IPR000742(EGF-like, type 3)|interpro:IPR000152(Aspartic acid and asparagine hydroxylation site)|interpro:IPR018097|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR036179|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR003599(Immunoglobulin subtype)|interpro:IPR013106(Immunoglobulin V-set)|interpro:IPR000538(Link)|interpro:IPR035976|interpro:IPR000436(Sushi/SCR/CCP)|rgd:619940	-	-	-	figure legend:ST1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10116(rat-brain-cerebellum)|taxid:10116(Rattus norvegicus)	-	2020/10/30	2020/10/30	rogid:DtE+ZXAZKdCMvUW5K+jXQ5bH07M10116	rogid:SPrTbe0RK9qQyJOchwzom6oejwo10116	rigid:OaXQ9NA25fwCWxejPU3Ao9q5j/E	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q5XIE8	uniprotkb:Q04462	intact:EBI-15348306|ensembl:ENSRNOP00000023037	intact:EBI-918152|uniprotkb:Q6MG65|ensembl:ENSRNOP00000001160|ensembl:ENSRNOP00000072696	psi-mi:itm2b_rat(display_long)|uniprotkb:Itm2b(gene name)|psi-mi:Itm2b(display_short)|uniprotkb:Immature BRI2(gene name synonym)|uniprotkb:Transmembrane protein BRI(gene name synonym)	psi-mi:syvc_rat(display_long)|uniprotkb:Vars1(gene name)|psi-mi:Vars1(display_short)|uniprotkb:Valyl-tRNA synthetase(gene name synonym)|uniprotkb:Vars(gene name synonym)|uniprotkb:Vars2(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Martins et al. (2018)	imex:IM-28469|pubmed:29476059	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26438079|imex:IM-28469-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSRNOG00000016271(gene)|ensembl:ENSRNOT00000023037(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001540"(amyloid-beta binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0010008"(endosome membrane)|go:"GO:0030660"(Golgi-associated vesicle membrane)|go:"GO:0031301"(integral component of organelle membrane)|go:"GO:0042985"(negative regulation of amyloid precursor protein biosynthetic process)|interpro:IPR007084(BRICHOS)|interpro:IPR040145|mint:Q5XIE8|refseq:NP_001006964.1|rgd:620727	rgd:3950|refseq:NP_445744.1|refseq:XP_006256109.1|ensembl:ENSRNOG00000000867(gene)|ensembl:ENSRNOT00000001160(transcript)|ensembl:ENSRNOT00000087861(transcript)|go:"GO:0002161"(aminoacyl-tRNA editing activity)|go:"GO:0004832"(valine-tRNA ligase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005829"(cytosol)|go:"GO:0006438"(valyl-tRNA aminoacylation)|interpro:IPR001412(Aminoacyl-tRNA synthetase, class I, conserved site)|interpro:IPR002300(Aminoacyl-tRNA synthetase, class Ia)|interpro:IPR002303(Valyl-tRNA synthetase, class Ia)|interpro:IPR004046(Glutathione S-transferase, C-terminal)|interpro:IPR009008(Valyl/Leucyl/Isoleucyl-tRNA synthetase, class Ia, editing)|interpro:IPR009080(Aminoacyl-tRNA synthetase, class 1a, anticodon-binding)|interpro:IPR010987(Glutathione S-transferase, C-terminal-like)|interpro:IPR013155(Valyl/Leucyl/Isoleucyl-tRNA synthetase, class I, anticodon-binding)|interpro:IPR014729(Rossmann-like alpha/beta/alpha sandwich fold)|interpro:IPR033705|interpro:IPR036282|interpro:IPR037118|mint:Q04462	-	-	-	figure legend:ST1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10116(rat-brain-cerebellum)|taxid:10116(Rattus norvegicus)	-	2020/10/30	2020/10/30	rogid:DtE+ZXAZKdCMvUW5K+jXQ5bH07M10116	rogid:MfDvMeOqEJmQ91kfIi2hfNZM1Bk10116	rigid:OaXQ9NA25fwCWxejPU3Ao9q5j/E	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q5XIE8	uniprotkb:Q793F9	intact:EBI-15348306|ensembl:ENSRNOP00000023037	intact:EBI-26437105	psi-mi:itm2b_rat(display_long)|uniprotkb:Itm2b(gene name)|psi-mi:Itm2b(display_short)|uniprotkb:Immature BRI2(gene name synonym)|uniprotkb:Transmembrane protein BRI(gene name synonym)	psi-mi:vps4a_rat(display_long)|uniprotkb:Vps4a(gene name)|psi-mi:Vps4a(display_short)|uniprotkb:vps4-A(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Martins et al. (2018)	imex:IM-28469|pubmed:29476059	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26438079|imex:IM-28469-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSRNOG00000016271(gene)|ensembl:ENSRNOT00000023037(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001540"(amyloid-beta binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0010008"(endosome membrane)|go:"GO:0030660"(Golgi-associated vesicle membrane)|go:"GO:0031301"(integral component of organelle membrane)|go:"GO:0042985"(negative regulation of amyloid precursor protein biosynthetic process)|interpro:IPR007084(BRICHOS)|interpro:IPR040145|mint:Q5XIE8|refseq:NP_001006964.1|rgd:620727	go:"GO:0007033"(vacuole organization)|go:"GO:0007080"(mitotic metaphase plate congression)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0009838"(abscission)|go:"GO:0010008"(endosome membrane)|go:"GO:0016192"(vesicle-mediated transport)|go:"GO:0016197"(endosomal transport)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030496"(midbody)|go:"GO:0031267"(small GTPase binding)|go:"GO:0031902"(late endosome membrane)|go:"GO:0032367"(intracellular cholesterol transport)|go:"GO:0032466"(negative regulation of cytokinesis)|go:"GO:0032880"(regulation of protein localization)|go:"GO:0034058"(endosomal vesicle fusion)|go:"GO:0036258"(multivesicular body assembly)|go:"GO:0039702"(viral budding via host ESCRT complex)|go:"GO:0043162"(ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway)|go:"GO:0006997"(nucleus organization)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0044878"(mitotic cytokinesis checkpoint signaling)|go:"GO:0046761"(viral budding from plasma membrane)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0048524"(positive regulation of viral process)|go:"GO:0051301"(cell division)|go:"GO:0061738"(late endosomal microautophagy)|go:"GO:0061952"(midbody abscission)|go:"GO:0072319"(vesicle uncoating)|go:"GO:0090543"(Flemming body)|go:"GO:0090611"(ubiquitin-independent protein catabolic process via the multivesicular body sorting pathway)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|go:"GO:1902188"(obsolete positive regulation of viral release from host cell)|go:"GO:1903076"(regulation of protein localization to plasma membrane)|go:"GO:1903543"(positive regulation of exosomal secretion)|go:"GO:1903774"(positive regulation of viral budding via host ESCRT complex)|go:"GO:1903902"(positive regulation of viral life cycle)|reactome:R-RNO-917729|reactome:R-RNO-9668328|go:"GO:0000922"(spindle pole)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005764"(lysosome)|go:"GO:0005768"(endosome)|go:"GO:0005769"(early endosome)|go:"GO:0005770"(late endosome)|go:"GO:0005774"(vacuolar membrane)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006622"(protein targeting to lysosome)|go:"GO:0006900"(vesicle budding from membrane)|interpro:IPR031255|mint:Q793F9|refseq:NP_663711.1|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR041569|interpro:IPR003959(AAA ATPase, core)|interpro:IPR003960(AAA ATPase, conserved site)|interpro:IPR007330(MIT)|interpro:IPR036181|interpro:IPR027417|interpro:IPR015415(Vps4 oligomerisation, C-terminal)|rgd:628810	-	-	-	figure legend:ST1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10116(rat-brain-cerebellum)|taxid:10116(Rattus norvegicus)	-	2020/10/30	2020/10/30	rogid:DtE+ZXAZKdCMvUW5K+jXQ5bH07M10116	rogid:g91HqrTCagG4SvpxkXmwa7XM+o010116	rigid:OaXQ9NA25fwCWxejPU3Ao9q5j/E	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q5XIE8	uniprotkb:Q62747	intact:EBI-15348306|ensembl:ENSRNOP00000023037	intact:EBI-16179541|ensembl:ENSRNOP00000040667|uniprotkb:F1M262|uniprotkb:Q99J98|uniprotkb:Q99P33|uniprotkb:Q99P34|uniprotkb:Q99P35|uniprotkb:Q99P36|uniprotkb:Q99P37|uniprotkb:Q99P38	psi-mi:itm2b_rat(display_long)|uniprotkb:Itm2b(gene name)|psi-mi:Itm2b(display_short)|uniprotkb:Immature BRI2(gene name synonym)|uniprotkb:Transmembrane protein BRI(gene name synonym)	psi-mi:syt7_rat(display_long)|uniprotkb:Syt7(gene name)|psi-mi:Syt7(display_short)|uniprotkb:Protein Syt7(gene name synonym)|uniprotkb:Synaptotagmin VII(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Martins et al. (2018)	imex:IM-28469|pubmed:29476059	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26438079|imex:IM-28469-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSRNOG00000016271(gene)|ensembl:ENSRNOT00000023037(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001540"(amyloid-beta binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0010008"(endosome membrane)|go:"GO:0030660"(Golgi-associated vesicle membrane)|go:"GO:0031301"(integral component of organelle membrane)|go:"GO:0042985"(negative regulation of amyloid precursor protein biosynthetic process)|interpro:IPR007084(BRICHOS)|interpro:IPR040145|mint:Q5XIE8|refseq:NP_001006964.1|rgd:620727	ensembl:ENSRNOG00000026432(gene)|ensembl:ENSRNOT00000048704(transcript)|go:"GO:0000149"(SNARE binding)|go:"GO:0001778"(plasma membrane repair)|go:"GO:0001786"(phosphatidylserine binding)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005513"(detection of calcium ion)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005544"(calcium-dependent phospholipid binding)|go:"GO:0005546"(phosphatidylinositol-4,5-bisphosphate binding)|go:"GO:0005764"(lysosome)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005777"(peroxisome)|go:"GO:0005778"(peroxisomal membrane)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006909"(phagocytosis)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0014059"(regulation of dopamine secretion)|go:"GO:0016192"(vesicle-mediated transport)|go:"GO:0017156"(calcium-ion regulated exocytosis)|go:"GO:0017158"(regulation of calcium ion-dependent exocytosis)|go:"GO:0019905"(syntaxin binding)|go:"GO:0030276"(clathrin binding)|go:"GO:0030425"(dendrite)|go:"GO:0030670"(phagocytic vesicle membrane)|go:"GO:0030672"(synaptic vesicle membrane)|go:"GO:0031045"(dense core granule)|go:"GO:0032009"(early phagosome)|go:"GO:0036465"(synaptic vesicle recycling)|go:"GO:0042734"(presynaptic membrane)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043195"(terminal bouton)|go:"GO:0043679"(axon terminus)|go:"GO:0045956"(positive regulation of calcium ion-dependent exocytosis)|go:"GO:0046850"(regulation of bone remodeling)|go:"GO:0048791"(calcium ion-regulated exocytosis of neurotransmitter)|go:"GO:0050764"(regulation of phagocytosis)|go:"GO:0050796"(regulation of insulin secretion)|go:"GO:0070092"(regulation of glucagon secretion)|go:"GO:0070382"(exocytic vesicle)|go:"GO:0071277"(cellular response to calcium ion)|go:"GO:0090119"(vesicle-mediated cholesterol transport)|go:"GO:0090385"(phagosome-lysosome fusion)|go:"GO:0098686"(hippocampal mossy fiber to CA3 synapse)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0098982"(GABA-ergic synapse)|go:"GO:0099056"(integral component of presynaptic membrane)|go:"GO:0099502"(calcium-dependent activation of synaptic vesicle fusion)|go:"GO:1900242"(regulation of synaptic vesicle endocytosis)|go:"GO:1990926"(short-term synaptic potentiation)|go:"GO:1990927"(calcium ion regulated lysosome exocytosis)|interpro:IPR000008(C2 calcium-dependent membrane targeting)|interpro:IPR001565(Synaptotagmin)|interpro:IPR015427(Synaptotagmin 7)|interpro:IPR035892|interpro:IPR037732|interpro:IPR037741|mint:Q62747|rcsb pdb:6ANJ|rcsb pdb:6ANK|rgd:62013|refseq:NP_067691.1|refseq:XP_006231127.1|refseq:XP_006231129.1|refseq:XP_006231130.1|dip:DIP-61710N	-	-	-	figure legend:ST1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10116(rat-brain-cerebellum)|taxid:10116(Rattus norvegicus)	-	2020/10/30	2020/10/30	rogid:DtE+ZXAZKdCMvUW5K+jXQ5bH07M10116	rogid:hvO8piahDgUsAOVC/EFIekjwh+M10116	rigid:OaXQ9NA25fwCWxejPU3Ao9q5j/E	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q5XIE8	uniprotkb:P29101	intact:EBI-15348306|ensembl:ENSRNOP00000023037	intact:EBI-458017	psi-mi:itm2b_rat(display_long)|uniprotkb:Itm2b(gene name)|psi-mi:Itm2b(display_short)|uniprotkb:Immature BRI2(gene name synonym)|uniprotkb:Transmembrane protein BRI(gene name synonym)	psi-mi:syt2_rat(display_long)|uniprotkb:Syt2(gene name)|psi-mi:Syt2(display_short)|uniprotkb:Synaptotagmin II(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Martins et al. (2018)	imex:IM-28469|pubmed:29476059	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26438079|imex:IM-28469-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSRNOG00000016271(gene)|ensembl:ENSRNOT00000023037(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001540"(amyloid-beta binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0010008"(endosome membrane)|go:"GO:0030660"(Golgi-associated vesicle membrane)|go:"GO:0031301"(integral component of organelle membrane)|go:"GO:0042985"(negative regulation of amyloid precursor protein biosynthetic process)|interpro:IPR007084(BRICHOS)|interpro:IPR040145|mint:Q5XIE8|refseq:NP_001006964.1|rgd:620727	rgd:3804|refseq:NP_036797.1|go:"GO:0000149"(SNARE binding)|go:"GO:0001786"(phosphatidylserine binding)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005544"(calcium-dependent phospholipid binding)|go:"GO:0005886"(plasma membrane)|go:"GO:0014059"(regulation of dopamine secretion)|go:"GO:0016079"(synaptic vesicle exocytosis)|go:"GO:0016192"(vesicle-mediated transport)|go:"GO:0017156"(calcium-ion regulated exocytosis)|go:"GO:0017158"(regulation of calcium ion-dependent exocytosis)|go:"GO:0019905"(syntaxin binding)|go:"GO:0030154"(cell differentiation)|go:"GO:0030276"(clathrin binding)|go:"GO:0030285"(integral component of synaptic vesicle membrane)|go:"GO:0030424"(axon)|go:"GO:0030672"(synaptic vesicle membrane)|interpro:IPR015428(Synaptotagmin 1,2)|interpro:IPR035892|rcsb pdb:2NM1|rcsb pdb:4ISR|go:"GO:0031045"(dense core granule)|reactome:R-RNO-8856825|reactome:R-RNO-8856828|go:"GO:0031594"(neuromuscular junction)|go:"GO:0042584"(chromaffin granule membrane)|go:"GO:0043195"(terminal bouton)|go:"GO:0043533"(inositol 1,3,4,5 tetrakisphosphate binding)|go:"GO:0048488"(synaptic vesicle endocytosis)|go:"GO:0048791"(calcium ion-regulated exocytosis of neurotransmitter)|go:"GO:0070382"(exocytic vesicle)|go:"GO:0071277"(cellular response to calcium ion)|go:"GO:0099502"(calcium-dependent activation of synaptic vesicle fusion)|go:"GO:1903861"(positive regulation of dendrite extension)|interpro:IPR000008(C2 calcium-dependent membrane targeting)|interpro:IPR001565(Synaptotagmin)|dip:DIP-32642N|mint:P29101	-	-	-	figure legend:ST1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10116(rat-brain-cerebellum)|taxid:10116(Rattus norvegicus)	-	2020/10/30	2020/10/30	rogid:DtE+ZXAZKdCMvUW5K+jXQ5bH07M10116	rogid:8gq8JFiYjNR21IjwMvs4cxgKIL010116	rigid:OaXQ9NA25fwCWxejPU3Ao9q5j/E	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q5XIE8	uniprotkb:P13086	intact:EBI-15348306|ensembl:ENSRNOP00000023037	intact:EBI-916468|uniprotkb:Q6P7S4	psi-mi:itm2b_rat(display_long)|uniprotkb:Itm2b(gene name)|psi-mi:Itm2b(display_short)|uniprotkb:Immature BRI2(gene name synonym)|uniprotkb:Transmembrane protein BRI(gene name synonym)	psi-mi:suca_rat(display_long)|uniprotkb:Succinyl-CoA synthetase subunit alpha(gene name synonym)|uniprotkb:Suclg1(gene name)|psi-mi:Suclg1(display_short)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Martins et al. (2018)	imex:IM-28469|pubmed:29476059	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26438079|imex:IM-28469-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSRNOG00000016271(gene)|ensembl:ENSRNOT00000023037(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001540"(amyloid-beta binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0010008"(endosome membrane)|go:"GO:0030660"(Golgi-associated vesicle membrane)|go:"GO:0031301"(integral component of organelle membrane)|go:"GO:0042985"(negative regulation of amyloid precursor protein biosynthetic process)|interpro:IPR007084(BRICHOS)|interpro:IPR040145|mint:Q5XIE8|refseq:NP_001006964.1|rgd:620727	go:"GO:0004775"("succinate-CoA ligase (ADP-forming) activity")|go:"GO:0004776"("succinate-CoA ligase (GDP-forming) activity")|go:"GO:0005739"(mitochondrion)|go:"GO:0006099"(tricarboxylic acid cycle)|go:"GO:0006104"(succinyl-CoA metabolic process)|go:"GO:0006105"(succinate metabolic process)|go:"GO:0009361"("succinate-CoA ligase complex (ADP-forming)")|go:"GO:0019003"(GDP binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045244"("succinate-CoA ligase complex (GDP-forming)")|reactome:R-RNO-71403|mint:P13086|rgd:619821|refseq:NP_446204.2|interpro:IPR017440(ATP-citrate lyase/succinyl-CoA ligase, active site)|interpro:IPR003781(CoA-binding)|interpro:IPR005810(Succinyl-CoA ligase, alpha subunit)|interpro:IPR005811(ATP-citrate lyase/succinyl-CoA ligase)|interpro:IPR016102(Succinyl-CoA synthetase-like)|interpro:IPR033847|interpro:IPR036291	-	-	-	figure legend:ST1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10116(rat-brain-cerebellum)|taxid:10116(Rattus norvegicus)	-	2020/10/30	2020/10/30	rogid:DtE+ZXAZKdCMvUW5K+jXQ5bH07M10116	rogid:DRQq0o+E21RHTJTPBltOD53IM2g10116	rigid:OaXQ9NA25fwCWxejPU3Ao9q5j/E	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q5XIE8	uniprotkb:P21913	intact:EBI-15348306|ensembl:ENSRNOP00000023037	intact:EBI-1225045|uniprotkb:B0BMZ2|uniprotkb:Q0QEZ3|ensembl:ENSRNOP00000010593	psi-mi:itm2b_rat(display_long)|uniprotkb:Itm2b(gene name)|psi-mi:Itm2b(display_short)|uniprotkb:Immature BRI2(gene name synonym)|uniprotkb:Transmembrane protein BRI(gene name synonym)	psi-mi:sdhb_rat(display_long)|uniprotkb:Sdhb(gene name)|psi-mi:Sdhb(display_short)|uniprotkb:Sdh1(gene name synonym)|uniprotkb:Iron-sulfur subunit of complex II(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Martins et al. (2018)	imex:IM-28469|pubmed:29476059	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26438079|imex:IM-28469-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSRNOG00000016271(gene)|ensembl:ENSRNOT00000023037(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001540"(amyloid-beta binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0010008"(endosome membrane)|go:"GO:0030660"(Golgi-associated vesicle membrane)|go:"GO:0031301"(integral component of organelle membrane)|go:"GO:0042985"(negative regulation of amyloid precursor protein biosynthetic process)|interpro:IPR007084(BRICHOS)|interpro:IPR040145|mint:Q5XIE8|refseq:NP_001006964.1|rgd:620727	rgd:1308598|refseq:NP_001094009.1|ensembl:ENSRNOG00000007967(gene)|ensembl:ENSRNOT00000010593(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005749"("mitochondrial respiratory chain complex II, succinate dehydrogenase complex (ubiquinone)")|go:"GO:0005886"(plasma membrane)|go:"GO:0006099"(tricarboxylic acid cycle)|go:"GO:0006105"(succinate metabolic process)|go:"GO:0008177"("succinate dehydrogenase (ubiquinone) activity")|go:"GO:0009055"(electron transfer activity)|go:"GO:0009060"(aerobic respiration)|go:"GO:0022904"(respiratory electron transport chain)|go:"GO:0031966"(mitochondrial membrane)|go:"GO:0045273"(respiratory chain complex II)|go:"GO:0046872"(metal ion binding)|go:"GO:0048039"(ubiquinone binding)|go:"GO:0051537"(2 iron, 2 sulfur cluster binding)|go:"GO:0051538"(3 iron, 4 sulfur cluster binding)|go:"GO:0051539"(4 iron, 4 sulfur cluster binding)|interpro:IPR001041(Ferredoxin)|interpro:IPR004489(Succinate dehydrogenase/fumarate reductase iron-sulphur protein)|interpro:IPR006058(2Fe-2S ferredoxin, iron-sulphur binding site)|interpro:IPR009051(Alpha-helical ferredoxin)|interpro:IPR012675(Beta-grasp fold, ferredoxin-type)|interpro:IPR017896|interpro:IPR017900|interpro:IPR025192|interpro:IPR036010|mint:P21913|reactome:R-RNO-71403|go:"GO:0005739"(mitochondrion)	-	-	-	figure legend:ST1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10116(rat-brain-cerebellum)|taxid:10116(Rattus norvegicus)	-	2020/10/30	2020/10/30	rogid:DtE+ZXAZKdCMvUW5K+jXQ5bH07M10116	rogid:uAB7GUGt1Auy9Q9Nvfp8x8xdJQM10116	rigid:OaXQ9NA25fwCWxejPU3Ao9q5j/E	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q5XIE8	uniprotkb:P23680	intact:EBI-15348306|ensembl:ENSRNOP00000023037	intact:EBI-26437075|uniprotkb:Q63539	psi-mi:itm2b_rat(display_long)|uniprotkb:Itm2b(gene name)|psi-mi:Itm2b(display_short)|uniprotkb:Immature BRI2(gene name synonym)|uniprotkb:Transmembrane protein BRI(gene name synonym)	psi-mi:samp_rat(display_long)|uniprotkb:Apcs(gene name)|psi-mi:Apcs(display_short)|uniprotkb:Ptx2(gene name synonym)|uniprotkb:Sap(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Martins et al. (2018)	imex:IM-28469|pubmed:29476059	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26438079|imex:IM-28469-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSRNOG00000016271(gene)|ensembl:ENSRNOT00000023037(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001540"(amyloid-beta binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0010008"(endosome membrane)|go:"GO:0030660"(Golgi-associated vesicle membrane)|go:"GO:0031301"(integral component of organelle membrane)|go:"GO:0042985"(negative regulation of amyloid precursor protein biosynthetic process)|interpro:IPR007084(BRICHOS)|interpro:IPR040145|mint:Q5XIE8|refseq:NP_001006964.1|rgd:620727	go:"GO:0001849"(complement component C1q complex binding)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005615"(extracellular space)|go:"GO:0006958"(complement activation, classical pathway)|go:"GO:0030169"(low-density lipoprotein particle binding)|go:"GO:0030246"(carbohydrate binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0044793"(negative regulation by host of viral process)|go:"GO:0044869"(negative regulation by host of viral exo-alpha-sialidase activity)|go:"GO:0044871"(negative regulation by host of viral glycoprotein metabolic process)|go:"GO:0045087"(innate immune response)|go:"GO:0045656"(negative regulation of monocyte differentiation)|go:"GO:0046597"(negative regulation of viral entry into host cell)|go:"GO:0046790"(virion binding)|go:"GO:0048525"(negative regulation of viral process)|go:"GO:0065003"(protein-containing complex assembly)|go:"GO:1903016"(negative regulation of exo-alpha-sialidase activity)|go:"GO:1903019"(negative regulation of glycoprotein metabolic process)|mint:P23680|refseq:NP_058866.2|interpro:IPR013320(Concanavalin A-like lectin/glucanase, subgroup)|interpro:IPR030476|interpro:IPR001759(Pentaxin)|rgd:68322	-	-	-	figure legend:ST1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10116(rat-brain-cerebellum)|taxid:10116(Rattus norvegicus)	-	2020/10/30	2020/10/30	rogid:DtE+ZXAZKdCMvUW5K+jXQ5bH07M10116	rogid:JgtdWvCOrSGp0pB5A+NME/knotc10116	rigid:OaXQ9NA25fwCWxejPU3Ao9q5j/E	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q5XIE8	uniprotkb:Q6P799	intact:EBI-15348306|ensembl:ENSRNOP00000023037	intact:EBI-919078|uniprotkb:Q8CIQ8|ensembl:ENSRNOP00000038448	psi-mi:itm2b_rat(display_long)|uniprotkb:Itm2b(gene name)|psi-mi:Itm2b(display_short)|uniprotkb:Immature BRI2(gene name synonym)|uniprotkb:Transmembrane protein BRI(gene name synonym)	psi-mi:sysc_rat(display_long)|uniprotkb:"Seryl-tRNA(Ser/Sec) synthetase"(gene name synonym)|uniprotkb:Sars1(gene name)|psi-mi:Sars1(display_short)|uniprotkb:Sars(gene name synonym)|uniprotkb:Seryl-tRNA synthetase(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Martins et al. (2018)	imex:IM-28469|pubmed:29476059	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26438079|imex:IM-28469-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSRNOG00000016271(gene)|ensembl:ENSRNOT00000023037(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001540"(amyloid-beta binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0010008"(endosome membrane)|go:"GO:0030660"(Golgi-associated vesicle membrane)|go:"GO:0031301"(integral component of organelle membrane)|go:"GO:0042985"(negative regulation of amyloid precursor protein biosynthetic process)|interpro:IPR007084(BRICHOS)|interpro:IPR040145|mint:Q5XIE8|refseq:NP_001006964.1|rgd:620727	rgd:628813|refseq:NP_001007607.1|ensembl:ENSRNOG00000020255(gene)|ensembl:ENSRNOT00000033015(transcript)|go:"GO:0000049"(tRNA binding)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0004828"(serine-tRNA ligase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006434"(seryl-tRNA aminoacylation)|go:"GO:0016525"(negative regulation of angiogenesis)|go:"GO:0019899"(enzyme binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0097056"("selenocysteinyl-tRNA(Sec) biosynthetic process")|go:"GO:1904046"(negative regulation of vascular endothelial growth factor production)|interpro:IPR002314("Aminoacyl-tRNA synthetase, class II (G, H, P and S)")|interpro:IPR002317(Seryl-tRNA synthetase, class IIa)|interpro:IPR006195(Aminoacyl-tRNA synthetase, class II)|interpro:IPR010978(tRNA-binding arm)|interpro:IPR015866(Seryl-tRNA synthetase, class IIa, N-terminal)|interpro:IPR033729|interpro:IPR042103|mint:Q6P799	-	-	-	figure legend:ST1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10116(rat-brain-cerebellum)|taxid:10116(Rattus norvegicus)	-	2020/10/30	2020/10/30	rogid:DtE+ZXAZKdCMvUW5K+jXQ5bH07M10116	rogid:eymWUFnZjGiLbirYSKsCTky8BXk10116	rigid:OaXQ9NA25fwCWxejPU3Ao9q5j/E	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q5XIE8	uniprotkb:G3V6S8	intact:EBI-15348306|ensembl:ENSRNOP00000023037	intact:EBI-22257503|ensembl:ENSRNOP00000008427|uniprotkb:Q5PQM1	psi-mi:itm2b_rat(display_long)|uniprotkb:Itm2b(gene name)|psi-mi:Itm2b(display_short)|uniprotkb:Immature BRI2(gene name synonym)|uniprotkb:Transmembrane protein BRI(gene name synonym)	psi-mi:srsf6_rat(display_long)|uniprotkb:Pre-mRNA-splicing factor SRP55(gene name synonym)|uniprotkb:Splicing factor, arginine/serine-rich 6(gene name synonym)|uniprotkb:Srsf6(gene name)|psi-mi:Srsf6(display_short)|uniprotkb:Sfrs6(gene name synonym)|uniprotkb:Srp55(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Martins et al. (2018)	imex:IM-28469|pubmed:29476059	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26438079|imex:IM-28469-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSRNOG00000016271(gene)|ensembl:ENSRNOT00000023037(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001540"(amyloid-beta binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0010008"(endosome membrane)|go:"GO:0030660"(Golgi-associated vesicle membrane)|go:"GO:0031301"(integral component of organelle membrane)|go:"GO:0042985"(negative regulation of amyloid precursor protein biosynthetic process)|interpro:IPR007084(BRICHOS)|interpro:IPR040145|mint:Q5XIE8|refseq:NP_001006964.1|rgd:620727	ensembl:ENSRNOG00000006380(gene)|ensembl:ENSRNOT00000008427(transcript)|go:"GO:0000380"(alternative mRNA splicing, via spliceosome)|go:"GO:0000381"(regulation of alternative mRNA splicing, via spliceosome)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0006376"(mRNA splice site selection)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0010837"(regulation of keratinocyte proliferation)|go:"GO:0016607"(nuclear speck)|go:"GO:0032868"(response to insulin)|go:"GO:0036002"(pre-mRNA binding)|go:"GO:0045617"(negative regulation of keratinocyte differentiation)|go:"GO:0048025"(negative regulation of mRNA splicing, via spliceosome)|go:"GO:0060501"(positive regulation of epithelial cell proliferation involved in lung morphogenesis)|go:"GO:0060548"(negative regulation of cell death)|go:"GO:0061041"(regulation of wound healing)|go:"GO:2000675"(negative regulation of type B pancreatic cell apoptotic process)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR029541|interpro:IPR034511|interpro:IPR035979|mint:G3V6S8|reactome:R-RNO-159236|reactome:R-RNO-72163|reactome:R-RNO-72165|reactome:R-RNO-72187|reactome:R-RNO-73856|refseq:NP_001014207.2|rgd:1359241	-	-	-	figure legend:ST1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10116(rat-brain-cerebellum)|taxid:10116(Rattus norvegicus)	-	2020/10/30	2020/10/30	rogid:DtE+ZXAZKdCMvUW5K+jXQ5bH07M10116	rogid:/l6R/Dpz2RgXmBU+qQerM46ZnRU10116	rigid:OaXQ9NA25fwCWxejPU3Ao9q5j/E	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q5XIE8	uniprotkb:Q9WVC0	intact:EBI-15348306|ensembl:ENSRNOP00000023037	intact:EBI-920205	psi-mi:itm2b_rat(display_long)|uniprotkb:Itm2b(gene name)|psi-mi:Itm2b(display_short)|uniprotkb:Immature BRI2(gene name synonym)|uniprotkb:Transmembrane protein BRI(gene name synonym)	psi-mi:sept7_rat(display_long)|uniprotkb:Septin7(gene name)|psi-mi:Septin7(display_short)|uniprotkb:CDC10 protein homolog(gene name synonym)|uniprotkb:Cdc10(gene name synonym)|uniprotkb:Sept7(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Martins et al. (2018)	imex:IM-28469|pubmed:29476059	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26438079|imex:IM-28469-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSRNOG00000016271(gene)|ensembl:ENSRNOT00000023037(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001540"(amyloid-beta binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0010008"(endosome membrane)|go:"GO:0030660"(Golgi-associated vesicle membrane)|go:"GO:0031301"(integral component of organelle membrane)|go:"GO:0042985"(negative regulation of amyloid precursor protein biosynthetic process)|interpro:IPR007084(BRICHOS)|interpro:IPR040145|mint:Q5XIE8|refseq:NP_001006964.1|rgd:620727	rgd:620469|refseq:NP_072138.2|interpro:IPR016491(Septin)|interpro:IPR008115(Septin 7)|interpro:IPR030379|go:"GO:0000281"(mitotic cytokinesis)|go:"GO:0000776"(kinetochore)|go:"GO:0001725"(stress fiber)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005819"(spindle)|go:"GO:0005930"(axoneme)|go:"GO:0005938"(cell cortex)|go:"GO:0005940"(septin ring)|go:"GO:0007283"(spermatogenesis)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0016020"(membrane)|go:"GO:0016476"(regulation of embryonic cell shape)|go:"GO:0030496"(midbody)|go:"GO:0030865"(cortical cytoskeleton organization)|go:"GO:0031105"(septin complex)|go:"GO:0031270"(pseudopodium retraction)|go:"GO:0032153"(cell division site)|go:"GO:0032154"(cleavage furrow)|go:"GO:0032156"(septin cytoskeleton)|go:"GO:0032160"(septin filament array)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034613"(cellular protein localization)|go:"GO:0042734"(presynaptic membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0043005"(neuron projection)|go:"GO:0043679"(axon terminus)|go:"GO:0044297"(cell body)|go:"GO:0045202"(synapse)|go:"GO:0048668"(collateral sprouting)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0060271"(cilium assembly)|go:"GO:0060997"(dendritic spine morphogenesis)|go:"GO:0061640"(cytoskeleton-dependent cytokinesis)|go:"GO:0097227"(sperm annulus)|go:"GO:0097730"(non-motile cilium)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099173"(postsynapse organization)|go:"GO:1902857"(positive regulation of non-motile cilium assembly)|reactome:R-RNO-5687128|mint:Q9WVC0|interpro:IPR027417	-	-	-	figure legend:ST1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10116(rat-brain-cerebellum)|taxid:10116(Rattus norvegicus)	-	2020/10/30	2020/10/30	rogid:DtE+ZXAZKdCMvUW5K+jXQ5bH07M10116	rogid:9EZtQeaSe4YkMHjuuPUXRvOTGGE10116	rigid:OaXQ9NA25fwCWxejPU3Ao9q5j/E	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q5XIE8	uniprotkb:O88453	intact:EBI-15348306|ensembl:ENSRNOP00000023037	intact:EBI-539530	psi-mi:itm2b_rat(display_long)|uniprotkb:Itm2b(gene name)|psi-mi:Itm2b(display_short)|uniprotkb:Immature BRI2(gene name synonym)|uniprotkb:Transmembrane protein BRI(gene name synonym)	psi-mi:safb1_rat(display_long)|uniprotkb:Safb(gene name)|psi-mi:Safb(display_short)|uniprotkb:Safb1(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Martins et al. (2018)	imex:IM-28469|pubmed:29476059	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26438079|imex:IM-28469-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSRNOG00000016271(gene)|ensembl:ENSRNOT00000023037(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001540"(amyloid-beta binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0010008"(endosome membrane)|go:"GO:0030660"(Golgi-associated vesicle membrane)|go:"GO:0031301"(integral component of organelle membrane)|go:"GO:0042985"(negative regulation of amyloid precursor protein biosynthetic process)|interpro:IPR007084(BRICHOS)|interpro:IPR040145|mint:Q5XIE8|refseq:NP_001006964.1|rgd:620727	rgd:620613|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR003034(DNA-binding SAP)|interpro:IPR035979|interpro:IPR036361|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0030520"(intracellular estrogen receptor signaling pathway)|go:"GO:0040008"(regulation of growth)|go:"GO:0042445"(hormone metabolic process)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0050684"(regulation of mRNA processing)|reactome:R-RNO-3899300|mint:O88453|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR034781	-	-	-	figure legend:ST1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10116(rat-brain-cerebellum)|taxid:10116(Rattus norvegicus)	-	2020/10/30	2020/10/30	rogid:DtE+ZXAZKdCMvUW5K+jXQ5bH07M10116	rogid:SsTl3FJ/eux+ekMPUc64dv6IWq410116	rigid:OaXQ9NA25fwCWxejPU3Ao9q5j/E	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q5XIE8	uniprotkb:Q62703	intact:EBI-15348306|ensembl:ENSRNOP00000023037	intact:EBI-9979590|uniprotkb:Q6P6X5|ensembl:ENSRNOP00000021817	psi-mi:itm2b_rat(display_long)|uniprotkb:Itm2b(gene name)|psi-mi:Itm2b(display_short)|uniprotkb:Immature BRI2(gene name synonym)|uniprotkb:Transmembrane protein BRI(gene name synonym)	psi-mi:rcn2_rat(display_long)|uniprotkb:Rcn2(gene name)|psi-mi:Rcn2(display_short)|uniprotkb:Erc55(gene name synonym)|uniprotkb:Calcium-binding protein ERC-55(gene name synonym)|uniprotkb:Taipoxin-associated calcium-binding protein 49(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Martins et al. (2018)	imex:IM-28469|pubmed:29476059	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26438079|imex:IM-28469-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSRNOG00000016271(gene)|ensembl:ENSRNOT00000023037(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001540"(amyloid-beta binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0010008"(endosome membrane)|go:"GO:0030660"(Golgi-associated vesicle membrane)|go:"GO:0031301"(integral component of organelle membrane)|go:"GO:0042985"(negative regulation of amyloid precursor protein biosynthetic process)|interpro:IPR007084(BRICHOS)|interpro:IPR040145|mint:Q5XIE8|refseq:NP_001006964.1|rgd:620727	refseq:NP_058828.2|rgd:3548|ensembl:ENSRNOG00000015780(gene)|ensembl:ENSRNOT00000021817(transcript)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005730"(nucleolus)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005788"(endoplasmic reticulum lumen)|interpro:IPR002048(Calcium-binding EF-hand)|interpro:IPR011992(EF-Hand type)|interpro:IPR018247|mint:Q62703	-	-	-	figure legend:ST1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10116(rat-brain-cerebellum)|taxid:10116(Rattus norvegicus)	-	2020/10/30	2020/10/30	rogid:DtE+ZXAZKdCMvUW5K+jXQ5bH07M10116	rogid:6sN8PDsM+GbuhxWQ3bEBdedfY3g10116	rigid:OaXQ9NA25fwCWxejPU3Ao9q5j/E	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q5XIE8	uniprotkb:P09527	intact:EBI-15348306|ensembl:ENSRNOP00000023037	intact:EBI-916225|uniprotkb:Q4AEF6|ensembl:ENSRNOP00000016432	psi-mi:itm2b_rat(display_long)|uniprotkb:Itm2b(gene name)|psi-mi:Itm2b(display_short)|uniprotkb:Immature BRI2(gene name synonym)|uniprotkb:Transmembrane protein BRI(gene name synonym)	psi-mi:rab7a_rat(display_long)|uniprotkb:Rab7a(gene name)|psi-mi:Rab7a(display_short)|uniprotkb:Ras-related protein p23(gene name synonym)|uniprotkb:Ras-related protein BRL-RAS(gene name synonym)|uniprotkb:Rab7(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Martins et al. (2018)	imex:IM-28469|pubmed:29476059	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26438079|imex:IM-28469-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSRNOG00000016271(gene)|ensembl:ENSRNOT00000023037(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001540"(amyloid-beta binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0010008"(endosome membrane)|go:"GO:0030660"(Golgi-associated vesicle membrane)|go:"GO:0031301"(integral component of organelle membrane)|go:"GO:0042985"(negative regulation of amyloid precursor protein biosynthetic process)|interpro:IPR007084(BRICHOS)|interpro:IPR040145|mint:Q5XIE8|refseq:NP_001006964.1|rgd:620727	rgd:61908|refseq:NP_076440.1|ensembl:ENSRNOG00000012247(gene)|ensembl:ENSRNOT00000016432(transcript)|go:"GO:0000045"(autophagosome assembly)|go:"GO:0000421"(autophagosome membrane)|go:"GO:0003924"(GTPase activity)|go:"GO:0003925"(G protein activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005764"(lysosome)|go:"GO:0005768"(endosome)|go:"GO:0005770"(late endosome)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005811"(lipid droplet)|go:"GO:0005829"(cytosol)|go:"GO:0006622"(protein targeting to lysosome)|go:"GO:0007174"(epidermal growth factor catabolic process)|go:"GO:0008333"(endosome to lysosome transport)|go:"GO:0010008"(endosome membrane)|go:"GO:0016042"(lipid catabolic process)|go:"GO:0019003"(GDP binding)|go:"GO:0019076"(viral release from host cell)|go:"GO:0022615"(protein to membrane docking)|go:"GO:0030670"(phagocytic vesicle membrane)|go:"GO:0031267"(small GTPase binding)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0031902"(late endosome membrane)|go:"GO:0032419"(extrinsic component of lysosome membrane)|go:"GO:0033162"(melanosome membrane)|go:"GO:0034045"(phagophore assembly site membrane)|go:"GO:0042147"(retrograde transport, endosome to Golgi)|go:"GO:0043195"(terminal bouton)|go:"GO:0045022"(early endosome to late endosome transport)|go:"GO:0045335"(phagocytic vesicle)|go:"GO:0045453"(bone resorption)|go:"GO:0045732"(positive regulation of protein catabolic process)|go:"GO:0048524"(positive regulation of viral process)|go:"GO:0051650"(establishment of vesicle localization)|go:"GO:0061724"(lipophagy)|go:"GO:0090383"(phagosome acidification)|go:"GO:0090385"(phagosome-lysosome fusion)|go:"GO:0097208"(alveolar lamellar body)|go:"GO:0098993"(anchored component of synaptic vesicle membrane)|go:"GO:0099638"(endosome to plasma membrane protein transport)|go:"GO:1903542"(negative regulation of exosomal secretion)|go:"GO:1903543"(positive regulation of exosomal secretion)|go:"GO:1905394"(retromer complex binding)|interpro:IPR001806(Ras GTPase)|interpro:IPR005225(Small GTP-binding protein)|interpro:IPR027417|mint:P09527|rcsb pdb:1VG0|rcsb pdb:1VG1|rcsb pdb:1VG8|rcsb pdb:1VG9|reactome:R-RNO-2132295|reactome:R-RNO-6798695|reactome:R-RNO-8854214|reactome:R-RNO-8873719|reactome:R-RNO-8876198|reactome:R-RNO-9013148|reactome:R-RNO-9013149|reactome:R-RNO-9013404|reactome:R-RNO-9013405|reactome:R-RNO-9013406|reactome:R-RNO-9013407|reactome:R-RNO-9013408|reactome:R-RNO-9013423|reactome:R-RNO-9035034|refseq:XP_006236911.1	-	-	-	figure legend:ST1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10116(rat-brain-cerebellum)|taxid:10116(Rattus norvegicus)	-	2020/10/30	2020/10/30	rogid:DtE+ZXAZKdCMvUW5K+jXQ5bH07M10116	rogid:lppyS2rWzk4Iax3nOHVdHiA0ceg10116	rigid:OaXQ9NA25fwCWxejPU3Ao9q5j/E	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q5XIE8	uniprotkb:M0RC99	intact:EBI-15348306|ensembl:ENSRNOP00000023037	intact:EBI-915664|uniprotkb:O88565	psi-mi:itm2b_rat(display_long)|uniprotkb:Itm2b(gene name)|psi-mi:Itm2b(display_short)|uniprotkb:Immature BRI2(gene name synonym)|uniprotkb:Transmembrane protein BRI(gene name synonym)	psi-mi:rab5a_rat(display_long)|uniprotkb:Rab5a(gene name)|psi-mi:Rab5a(display_short)|uniprotkb:Small GTP-binding protein rab5(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Martins et al. (2018)	imex:IM-28469|pubmed:29476059	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26438079|imex:IM-28469-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSRNOG00000016271(gene)|ensembl:ENSRNOT00000023037(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001540"(amyloid-beta binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0010008"(endosome membrane)|go:"GO:0030660"(Golgi-associated vesicle membrane)|go:"GO:0031301"(integral component of organelle membrane)|go:"GO:0042985"(negative regulation of amyloid precursor protein biosynthetic process)|interpro:IPR007084(BRICHOS)|interpro:IPR040145|mint:Q5XIE8|refseq:NP_001006964.1|rgd:620727	interpro:IPR005225(Small GTP-binding protein)|interpro:IPR001806(Ras GTPase)|refseq:NP_073183.1|refseq:XP_003751425.1|refseq:XP_003752788.1|interpro:IPR027417|rgd:620936|mint:M0RC99|go:"GO:0001726"(ruffle)|go:"GO:0003924"(GTPase activity)|go:"GO:0003925"(G protein activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005769"(early endosome)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006897"(endocytosis)|go:"GO:0006909"(phagocytosis)|go:"GO:0007032"(endosome organization)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0010008"(endosome membrane)|go:"GO:0012505"(endomembrane system)|go:"GO:0014911"(positive regulation of smooth muscle cell migration)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0016192"(vesicle-mediated transport)|go:"GO:0019001"(guanyl nucleotide binding)|go:"GO:0019003"(GDP binding)|go:"GO:0030100"(regulation of endocytosis)|go:"GO:0030139"(endocytic vesicle)|go:"GO:0030424"(axon)|go:"GO:0030425"(dendrite)|go:"GO:0030670"(phagocytic vesicle membrane)|go:"GO:0032009"(early phagosome)|go:"GO:0032991"(protein-containing complex)|go:"GO:0036465"(synaptic vesicle recycling)|go:"GO:0036477"(somatodendritic compartment)|go:"GO:0039694"(viral RNA genome replication)|go:"GO:0042470"(melanosome)|go:"GO:0042589"(zymogen granule membrane)|go:"GO:0043005"(neuron projection)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043195"(terminal bouton)|go:"GO:0043679"(axon terminus)|go:"GO:0045022"(early endosome to late endosome transport)|go:"GO:0045121"(membrane raft)|go:"GO:0045335"(phagocytic vesicle)|go:"GO:0045921"(positive regulation of exocytosis)|go:"GO:0048169"(regulation of long-term neuronal synaptic plasticity)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0048661"(positive regulation of smooth muscle cell proliferation)|go:"GO:0051021"(GDP-dissociation inhibitor binding)|go:"GO:0051036"(regulation of endosome size)|go:"GO:0051489"(regulation of filopodium assembly)|go:"GO:0055037"(recycling endosome)|go:"GO:0098559"(cytoplasmic side of early endosome membrane)|go:"GO:0098842"(postsynaptic early endosome)|go:"GO:0098993"(anchored component of synaptic vesicle membrane)|go:"GO:0150093"(amyloid-beta clearance by transcytosis)|go:"GO:2000286"(receptor internalization involved in canonical Wnt signaling pathway)|go:"GO:2000300"(regulation of synaptic vesicle exocytosis)	-	-	-	figure legend:ST1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10116(rat-brain-cerebellum)|taxid:10116(Rattus norvegicus)	-	2020/10/30	2020/10/30	rogid:DtE+ZXAZKdCMvUW5K+jXQ5bH07M10116	rogid:YQ/5pW5C9bIfRqb10F4QJKJXrGI10116	rigid:OaXQ9NA25fwCWxejPU3Ao9q5j/E	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q5XIE8	uniprotkb:P10536	intact:EBI-15348306|ensembl:ENSRNOP00000023037	intact:EBI-916259	psi-mi:itm2b_rat(display_long)|uniprotkb:Itm2b(gene name)|psi-mi:Itm2b(display_short)|uniprotkb:Immature BRI2(gene name synonym)|uniprotkb:Transmembrane protein BRI(gene name synonym)	psi-mi:rab1b_rat(display_long)|uniprotkb:Rab1b(gene name)|psi-mi:Rab1b(display_short)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Martins et al. (2018)	imex:IM-28469|pubmed:29476059	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26438079|imex:IM-28469-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSRNOG00000016271(gene)|ensembl:ENSRNOT00000023037(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001540"(amyloid-beta binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0010008"(endosome membrane)|go:"GO:0030660"(Golgi-associated vesicle membrane)|go:"GO:0031301"(integral component of organelle membrane)|go:"GO:0042985"(negative regulation of amyloid precursor protein biosynthetic process)|interpro:IPR007084(BRICHOS)|interpro:IPR040145|mint:Q5XIE8|refseq:NP_001006964.1|rgd:620727	go:"GO:0000045"(autophagosome assembly)|go:"GO:0003924"(GTPase activity)|go:"GO:0003925"(G protein activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005793"(endoplasmic reticulum-Golgi intermediate compartment)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0012505"(endomembrane system)|go:"GO:0019068"(virion assembly)|go:"GO:0034045"(phagophore assembly site membrane)|go:"GO:0045202"(synapse)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:1903020"(positive regulation of glycoprotein metabolic process)|go:"GO:2000785"(regulation of autophagosome assembly)|reactome:R-RNO-162658|reactome:R-RNO-204005|reactome:R-RNO-6807878|reactome:R-RNO-6811434|reactome:R-RNO-8873719|reactome:R-RNO-8876198|mint:P10536|interpro:IPR005225(Small GTP-binding protein)|interpro:IPR001806(Ras GTPase)|interpro:IPR027417|rgd:1642882	-	-	-	figure legend:ST1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10116(rat-brain-cerebellum)|taxid:10116(Rattus norvegicus)	-	2020/10/30	2020/10/30	rogid:DtE+ZXAZKdCMvUW5K+jXQ5bH07M10116	rogid:38K2G7MLSF0vWuSRaxk2wbqmqwI10116	rigid:OaXQ9NA25fwCWxejPU3Ao9q5j/E	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q5XIE8	uniprotkb:P23606	intact:EBI-15348306|ensembl:ENSRNOP00000023037	intact:EBI-26437041|ensembl:ENSRNOP00000027315|uniprotkb:Q4QRA6	psi-mi:itm2b_rat(display_long)|uniprotkb:Itm2b(gene name)|psi-mi:Itm2b(display_short)|uniprotkb:Immature BRI2(gene name synonym)|uniprotkb:Transmembrane protein BRI(gene name synonym)	psi-mi:tgm1_rat(display_long)|uniprotkb:Tgm1(gene name)|psi-mi:Tgm1(display_short)|uniprotkb:Epidermal TGase(gene name synonym)|uniprotkb:Transglutaminase K(gene name synonym)|uniprotkb:Transglutaminase-1(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Martins et al. (2018)	imex:IM-28469|pubmed:29476059	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26438079|imex:IM-28469-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSRNOG00000016271(gene)|ensembl:ENSRNOT00000023037(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001540"(amyloid-beta binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0010008"(endosome membrane)|go:"GO:0030660"(Golgi-associated vesicle membrane)|go:"GO:0031301"(integral component of organelle membrane)|go:"GO:0042985"(negative regulation of amyloid precursor protein biosynthetic process)|interpro:IPR007084(BRICHOS)|interpro:IPR040145|mint:Q5XIE8|refseq:NP_001006964.1|rgd:620727	ensembl:ENSRNOG00000020136(gene)|ensembl:ENSRNOT00000027315(transcript)|go:"GO:0003810"(protein-glutamine gamma-glutamyltransferase activity)|go:"GO:0005912"(adherens junction)|go:"GO:0009887"(animal organ morphogenesis)|go:"GO:0010838"(positive regulation of keratinocyte proliferation)|go:"GO:0016020"(membrane)|go:"GO:0018149"(peptide cross-linking)|go:"GO:0030216"(keratinocyte differentiation)|go:"GO:0031224"(intrinsic component of membrane)|go:"GO:0031424"(keratinization)|go:"GO:0042802"(identical protein binding)|go:"GO:0045787"(positive regulation of cell cycle)|go:"GO:0046872"(metal ion binding)|interpro:IPR001102(Transglutaminase, N-terminal)|interpro:IPR002931(Transglutaminase-like)|interpro:IPR008958(Transglutaminase, C-terminal)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR013808(Transglutaminase, conserved site)|interpro:IPR014756(Immunoglobulin E-set)|interpro:IPR023608|interpro:IPR036238|interpro:IPR036985|mint:P23606|reactome:R-RNO-6809371|interpro:IPR038765|refseq:NP_113847.1|refseq:XP_006252076.1|refseq:XP_008768913.1|rgd:61838	-	-	-	figure legend:ST1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10116(rat-brain-cerebellum)|taxid:10116(Rattus norvegicus)	-	2020/10/30	2020/10/30	rogid:DtE+ZXAZKdCMvUW5K+jXQ5bH07M10116	rogid:j6muOwVqMZ+86lt0zEYWrI8YwII10116	rigid:OaXQ9NA25fwCWxejPU3Ao9q5j/E	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q5XIE8	uniprotkb:P04785	intact:EBI-15348306|ensembl:ENSRNOP00000023037	intact:EBI-915861|uniprotkb:P13700|ensembl:ENSRNOP00000051841	psi-mi:itm2b_rat(display_long)|uniprotkb:Itm2b(gene name)|psi-mi:Itm2b(display_short)|uniprotkb:Immature BRI2(gene name synonym)|uniprotkb:Transmembrane protein BRI(gene name synonym)	psi-mi:pdia1_rat(display_long)|uniprotkb:Prolyl 4-hydroxylase subunit beta(gene name synonym)|uniprotkb:Cellular thyroid hormone-binding protein(gene name synonym)|uniprotkb:P4hb(gene name)|psi-mi:P4hb(display_short)|uniprotkb:Pdia1(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Martins et al. (2018)	imex:IM-28469|pubmed:29476059	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26438079|imex:IM-28469-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSRNOG00000016271(gene)|ensembl:ENSRNOT00000023037(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001540"(amyloid-beta binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0010008"(endosome membrane)|go:"GO:0030660"(Golgi-associated vesicle membrane)|go:"GO:0031301"(integral component of organelle membrane)|go:"GO:0042985"(negative regulation of amyloid precursor protein biosynthetic process)|interpro:IPR007084(BRICHOS)|interpro:IPR040145|mint:Q5XIE8|refseq:NP_001006964.1|rgd:620727	refseq:NP_037130.2|rgd:3244|ensembl:ENSRNOG00000036689(gene)|ensembl:ENSRNOT00000054958(transcript)|go:"GO:0003756"(protein disulfide isomerase activity)|go:"GO:0003779"(actin binding)|go:"GO:0004656"(procollagen-proline 4-dioxygenase activity)|go:"GO:0005178"(integrin binding)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005788"(endoplasmic reticulum lumen)|go:"GO:0005793"(endoplasmic reticulum-Golgi intermediate compartment)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0006457"(protein folding)|go:"GO:0009897"(external side of plasma membrane)|go:"GO:0015035"(protein-disulfide reductase activity)|go:"GO:0016222"(procollagen-proline 4-dioxygenase complex)|go:"GO:0016972"(thiol oxidase activity)|go:"GO:0018401"(peptidyl-proline hydroxylation to 4-hydroxy-L-proline)|go:"GO:0019899"(enzyme binding)|go:"GO:0030027"(lamellipodium)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034663"(endoplasmic reticulum chaperone complex)|go:"GO:0034975"(protein folding in endoplasmic reticulum)|go:"GO:0034976"(response to endoplasmic reticulum stress)|go:"GO:0042470"(melanosome)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045785"(positive regulation of cell adhesion)|go:"GO:0046598"(positive regulation of viral entry into host cell)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0071456"(cellular response to hypoxia)|go:"GO:0098761"(cellular response to interleukin-7)|go:"GO:1900026"(positive regulation of substrate adhesion-dependent cell spreading)|go:"GO:1902175"(regulation of oxidative stress-induced intrinsic apoptotic signaling pathway)|interpro:IPR005788(Disulphide isomerase)|interpro:IPR005792(Protein disulphide isomerase)|interpro:IPR013766(Thioredoxin domain)|interpro:IPR017937|interpro:IPR036249|mint:P04785|reactome:R-RNO-1650814|reactome:R-RNO-3299685|reactome:R-RNO-381426|reactome:R-RNO-5358346|reactome:R-RNO-8866423|reactome:R-RNO-8957275|reactome:R-RNO-8963888|reactome:R-RNO-9020591|reactome:R-RNO-9020933	-	-	-	figure legend:ST1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10116(rat-brain-cerebellum)|taxid:10116(Rattus norvegicus)	-	2020/10/30	2020/10/30	rogid:DtE+ZXAZKdCMvUW5K+jXQ5bH07M10116	rogid:nXaUDIKzWIRQ95lFxT0hB0T9enQ10116	rigid:OaXQ9NA25fwCWxejPU3Ao9q5j/E	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q5XIE8	uniprotkb:P04961	intact:EBI-15348306|ensembl:ENSRNOP00000023037	intact:EBI-1208689|ensembl:ENSRNOP00000028887	psi-mi:itm2b_rat(display_long)|uniprotkb:Itm2b(gene name)|psi-mi:Itm2b(display_short)|uniprotkb:Immature BRI2(gene name synonym)|uniprotkb:Transmembrane protein BRI(gene name synonym)	psi-mi:pcna_rat(display_long)|uniprotkb:Pcna(gene name)|psi-mi:Pcna(display_short)|uniprotkb:Cyclin(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Martins et al. (2018)	imex:IM-28469|pubmed:29476059	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26438079|imex:IM-28469-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSRNOG00000016271(gene)|ensembl:ENSRNOT00000023037(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001540"(amyloid-beta binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0010008"(endosome membrane)|go:"GO:0030660"(Golgi-associated vesicle membrane)|go:"GO:0031301"(integral component of organelle membrane)|go:"GO:0042985"(negative regulation of amyloid precursor protein biosynthetic process)|interpro:IPR007084(BRICHOS)|interpro:IPR040145|mint:Q5XIE8|refseq:NP_001006964.1|rgd:620727	rgd:3269|refseq:NP_071776.1|ensembl:ENSRNOG00000021264(gene)|ensembl:ENSRNOT00000028887(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000307"(cyclin-dependent protein kinase holoenzyme complex)|go:"GO:0000701"(purine-specific mismatch base pair DNA N-glycosylase activity)|go:"GO:0000785"(chromatin)|go:"GO:0003682"(chromatin binding)|go:"GO:0003684"(damaged DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005652"(nuclear lamina)|go:"GO:0005657"(replication fork)|go:"GO:0005813"(centrosome)|go:"GO:0006272"(leading strand elongation)|go:"GO:0006287"(base-excision repair, gap-filling)|go:"GO:0006298"(mismatch repair)|go:"GO:0006979"(response to oxidative stress)|go:"GO:0007507"(heart development)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0016604"(nuclear body)|go:"GO:0019899"(enzyme binding)|go:"GO:0019985"(translesion synthesis)|go:"GO:0030331"(estrogen receptor binding)|go:"GO:0030337"(DNA polymerase processivity factor activity)|go:"GO:0030855"(epithelial cell differentiation)|go:"GO:0030971"(receptor tyrosine kinase binding)|go:"GO:0031297"(replication fork processing)|go:"GO:0032077"(positive regulation of deoxyribonuclease activity)|go:"GO:0032139"(dinucleotide insertion or deletion binding)|go:"GO:0032355"(response to estradiol)|go:"GO:0032405"(MutLalpha complex binding)|go:"GO:0033993"(response to lipid)|go:"GO:0034644"(cellular response to UV)|go:"GO:0035035"(histone acetyltransferase binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0043596"(nuclear replication fork)|go:"GO:0044849"(estrous cycle)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045739"(positive regulation of DNA repair)|go:"GO:0045740"(positive regulation of DNA replication)|go:"GO:0046686"(response to cadmium ion)|go:"GO:0070182"(DNA polymerase binding)|go:"GO:0070301"(cellular response to hydrogen peroxide)|go:"GO:0070557"(PCNA-p21 complex)|go:"GO:0071466"(cellular response to xenobiotic stimulus)|go:"GO:0071548"(response to dexamethasone)|go:"GO:0097421"(liver regeneration)|go:"GO:1900264"(positive regulation of DNA-directed DNA polymerase activity)|go:"GO:1902065"(response to L-glutamate)|go:"GO:1902990"(mitotic telomere maintenance via semi-conservative replication)|interpro:IPR000730(Proliferating cell nuclear antigen, PCNA)|interpro:IPR022648|interpro:IPR022649|interpro:IPR022659|mint:P04961|reactome:R-RNO-110312|go:"GO:0043626"(PCNA complex)|reactome:R-RNO-110320|reactome:R-RNO-174411|reactome:R-RNO-174414|reactome:R-RNO-174417|reactome:R-RNO-174437|reactome:R-RNO-4615885|reactome:R-RNO-5358565|reactome:R-RNO-5651801|reactome:R-RNO-5655862|reactome:R-RNO-5656121|reactome:R-RNO-5656169|reactome:R-RNO-5685942|reactome:R-RNO-110314|reactome:R-RNO-5696397|reactome:R-RNO-5696400|reactome:R-RNO-6782135|reactome:R-RNO-6782210|reactome:R-RNO-6804114|reactome:R-RNO-69091|reactome:R-RNO-69166|reactome:R-RNO-69183	-	-	-	figure legend:ST1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10116(rat-brain-cerebellum)|taxid:10116(Rattus norvegicus)	-	2020/10/30	2020/10/30	rogid:DtE+ZXAZKdCMvUW5K+jXQ5bH07M10116	rogid:DX0r1yyUhv7sE2J4ogqvwXtvNDk10116	rigid:OaXQ9NA25fwCWxejPU3Ao9q5j/E	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q5XIE8	uniprotkb:P48679	intact:EBI-15348306|ensembl:ENSRNOP00000023037	intact:EBI-917618	psi-mi:itm2b_rat(display_long)|uniprotkb:Itm2b(gene name)|psi-mi:Itm2b(display_short)|uniprotkb:Immature BRI2(gene name synonym)|uniprotkb:Transmembrane protein BRI(gene name synonym)	psi-mi:lmna_rat(display_long)|uniprotkb:Lmna(gene name)|psi-mi:Lmna(display_short)|uniprotkb:Lmn1(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Martins et al. (2018)	imex:IM-28469|pubmed:29476059	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26438079|imex:IM-28469-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSRNOG00000016271(gene)|ensembl:ENSRNOT00000023037(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001540"(amyloid-beta binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0010008"(endosome membrane)|go:"GO:0030660"(Golgi-associated vesicle membrane)|go:"GO:0031301"(integral component of organelle membrane)|go:"GO:0042985"(negative regulation of amyloid precursor protein biosynthetic process)|interpro:IPR007084(BRICHOS)|interpro:IPR040145|mint:Q5XIE8|refseq:NP_001006964.1|rgd:620727	rgd:620456|interpro:IPR001322(Intermediate filament, C-terminal)|interpro:IPR018039|mint:P48679|interpro:IPR039008|interpro:IPR036415|go:"GO:0005634"(nucleus)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005638"(lamin filament)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0006997"(nucleus organization)|go:"GO:0006998"(nuclear envelope organization)|go:"GO:0007283"(spermatogenesis)|go:"GO:0008157"(protein phosphatase 1 binding)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0009612"(response to mechanical stimulus)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0016363"(nuclear matrix)|go:"GO:0030334"(regulation of cell migration)|go:"GO:0030951"(establishment or maintenance of microtubule cytoskeleton polarity)|go:"GO:0031647"(regulation of protein stability)|go:"GO:0031965"(nuclear membrane)|go:"GO:0034504"(protein localization to nucleus)|go:"GO:0035861"(site of double-strand break)|go:"GO:0045669"(positive regulation of osteoblast differentiation)|go:"GO:0055015"(ventricular cardiac muscle cell development)|go:"GO:0071456"(cellular response to hypoxia)|go:"GO:0072201"(negative regulation of mesenchymal cell proliferation)|go:"GO:0090201"(negative regulation of release of cytochrome c from mitochondria)|go:"GO:0090343"(positive regulation of cell aging)|go:"GO:0090398"(cellular senescence)|go:"GO:1900114"(positive regulation of histone H3-K9 trimethylation)|go:"GO:1900180"(regulation of protein localization to nucleus)|go:"GO:1903243"(negative regulation of cardiac muscle hypertrophy in response to stress)|go:"GO:1904178"(negative regulation of adipose tissue development)|go:"GO:1990683"(DNA double-strand break attachment to nuclear envelope)|go:"GO:2001237"(negative regulation of extrinsic apoptotic signaling pathway)|reactome:R-RNO-352238|reactome:R-RNO-4419969	-	-	-	figure legend:ST1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10116(rat-brain-cerebellum)|taxid:10116(Rattus norvegicus)	-	2020/10/30	2020/10/30	rogid:DtE+ZXAZKdCMvUW5K+jXQ5bH07M10116	rogid:WBZq/9WdHqQmDRy0uyBn0AZjvY810116	rigid:OaXQ9NA25fwCWxejPU3Ao9q5j/E	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q5XIE8	uniprotkb:Q9EPH8	intact:EBI-15348306|ensembl:ENSRNOP00000023037	intact:EBI-919825|ensembl:ENSRNOP00000012775	psi-mi:itm2b_rat(display_long)|uniprotkb:Itm2b(gene name)|psi-mi:Itm2b(display_short)|uniprotkb:Immature BRI2(gene name synonym)|uniprotkb:Transmembrane protein BRI(gene name synonym)	psi-mi:pabp1_rat(display_long)|uniprotkb:Pabpc1(gene name)|psi-mi:Pabpc1(display_short)|uniprotkb:Pabp1(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Martins et al. (2018)	imex:IM-28469|pubmed:29476059	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26438079|imex:IM-28469-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSRNOG00000016271(gene)|ensembl:ENSRNOT00000023037(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001540"(amyloid-beta binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0010008"(endosome membrane)|go:"GO:0030660"(Golgi-associated vesicle membrane)|go:"GO:0031301"(integral component of organelle membrane)|go:"GO:0042985"(negative regulation of amyloid precursor protein biosynthetic process)|interpro:IPR007084(BRICHOS)|interpro:IPR040145|mint:Q5XIE8|refseq:NP_001006964.1|rgd:620727	rgd:619838|refseq:NP_599180.1|ensembl:ENSRNOG00000008639(gene)|ensembl:ENSRNOT00000012775(transcript)|go:"GO:0000184"(nuclear-transcribed mRNA catabolic process, nonsense-mediated decay)|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0003730"(mRNA 3'-UTR binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006397"(mRNA processing)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008143"("poly(A) binding")|go:"GO:0008266"("poly(U) RNA binding")|go:"GO:0008380"(RNA splicing)|go:"GO:0010494"(cytoplasmic stress granule)|go:"GO:0030027"(lamellipodium)|go:"GO:0030425"(dendrite)|go:"GO:0031047"(gene silencing by RNA)|go:"GO:0031252"(cell leading edge)|go:"GO:0036464"(cytoplasmic ribonucleoprotein granule)|go:"GO:0045070"(positive regulation of viral genome replication)|go:"GO:0045202"(synapse)|go:"GO:0060213"("positive regulation of nuclear-transcribed mRNA poly(A) tail shortening")|go:"GO:0071013"(catalytic step 2 spliceosome)|go:"GO:1900153"(positive regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay)|go:"GO:1990124"(messenger ribonucleoprotein complex)|go:"GO:1990904"(ribonucleoprotein complex)|go:"GO:2000623"(negative regulation of nuclear-transcribed mRNA catabolic process, nonsense-mediated decay)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR002004(Polyadenylate-binding protein/Hyperplastic disc protein)|interpro:IPR003954(RNA recognition, region 1)|interpro:IPR006515(Polyadenylate binding protein, human types 1, 2, 3, 4)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR035979|interpro:IPR036053|mint:Q9EPH8|reactome:R-RNO-156827|reactome:R-RNO-429947|reactome:R-RNO-450408|reactome:R-RNO-72649|reactome:R-RNO-975956|reactome:R-RNO-975957	-	-	-	figure legend:ST1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10116(rat-brain-cerebellum)|taxid:10116(Rattus norvegicus)	-	2020/10/30	2020/10/30	rogid:DtE+ZXAZKdCMvUW5K+jXQ5bH07M10116	rogid:SEu6ZUy3fI2xh8x9pqs+9OCtt+M10116	rigid:OaXQ9NA25fwCWxejPU3Ao9q5j/E	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q5XIE8	uniprotkb:Q9QVC8	intact:EBI-15348306|ensembl:ENSRNOP00000023037	intact:EBI-15833372|ensembl:ENSRNOP00000008737|uniprotkb:A6IM14|uniprotkb:Q8K3U8	psi-mi:itm2b_rat(display_long)|uniprotkb:Itm2b(gene name)|psi-mi:Itm2b(display_short)|uniprotkb:Immature BRI2(gene name synonym)|uniprotkb:Transmembrane protein BRI(gene name synonym)	psi-mi:fkbp4_rat(display_long)|uniprotkb:Fkbp4(gene name)|psi-mi:Fkbp4(display_short)|uniprotkb:Fkbp52(gene name synonym)|uniprotkb:52 kDa FK506-binding protein(gene name synonym)|uniprotkb:59 kDa immunophilin(gene name synonym)|uniprotkb:FK506-binding protein 4(gene name synonym)|uniprotkb:FKBP59(gene name synonym)|uniprotkb:HSP-binding immunophilin(gene name synonym)|uniprotkb:Immunophilin FKBP52(gene name synonym)|uniprotkb:Rotamase(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Martins et al. (2018)	imex:IM-28469|pubmed:29476059	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26438079|imex:IM-28469-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSRNOG00000016271(gene)|ensembl:ENSRNOT00000023037(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001540"(amyloid-beta binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0010008"(endosome membrane)|go:"GO:0030660"(Golgi-associated vesicle membrane)|go:"GO:0031301"(integral component of organelle membrane)|go:"GO:0042985"(negative regulation of amyloid precursor protein biosynthetic process)|interpro:IPR007084(BRICHOS)|interpro:IPR040145|mint:Q5XIE8|refseq:NP_001006964.1|rgd:620727	ensembl:ENSRNOG00000006444(gene)|ensembl:ENSRNOT00000008737(transcript)|go:"GO:0000413"(protein peptidyl-prolyl isomerization)|go:"GO:0003755"(peptidyl-prolyl cis-trans isomerase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005525"(GTP binding)|go:"GO:0005528"(FK506 binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0005874"(microtubule)|go:"GO:0006463"(steroid hormone receptor complex assembly)|go:"GO:0006825"(copper ion transport)|go:"GO:0007566"(embryo implantation)|go:"GO:0010977"(negative regulation of neuron projection development)|go:"GO:0030521"(androgen receptor signaling pathway)|go:"GO:0030850"(prostate gland development)|go:"GO:0031072"(heat shock protein binding)|go:"GO:0031111"(negative regulation of microtubule polymerization or depolymerization)|go:"GO:0031115"(negative regulation of microtubule polymerization)|go:"GO:0031503"(protein-containing complex localization)|go:"GO:0032767"(copper-dependent protein binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035259"(glucocorticoid receptor binding)|go:"GO:0043005"(neuron projection)|go:"GO:0043025"(neuronal cell body)|go:"GO:0044295"(axonal growth cone)|go:"GO:0046661"(male sex differentiation)|go:"GO:0048156"(tau protein binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0048608"(reproductive structure development)|go:"GO:0051219"(phosphoprotein binding)|go:"GO:0061077"(chaperone-mediated protein folding)|interpro:IPR001179(Peptidyl-prolyl cis-trans isomerase, FKBP-type)|interpro:IPR001440(Tetratricopeptide TPR-1)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR013105(Tetratricopeptide TPR2)|interpro:IPR019734|interpro:IPR031212|mint:Q9QVC8|reactome:R-RNO-3371497|reactome:R-RNO-3371568|reactome:R-RNO-8939211|reactome:R-RNO-9018519|refseq:NP_001178792.1|dip:DIP-59214N|rgd:628729	-	-	-	figure legend:ST1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10116(rat-brain-cerebellum)|taxid:10116(Rattus norvegicus)	-	2020/10/30	2020/10/30	rogid:DtE+ZXAZKdCMvUW5K+jXQ5bH07M10116	rogid:vwtyeDHbJffl3vqLdQN/BTl9v8M10116	rigid:OaXQ9NA25fwCWxejPU3Ao9q5j/E	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q5XIE8	uniprotkb:P10111	intact:EBI-15348306|ensembl:ENSRNOP00000023037	intact:EBI-4533302|uniprotkb:P18303|uniprotkb:Q5BK98|ensembl:ENSRNOP00000071404|ensembl:ENSRNOP00000073930	psi-mi:itm2b_rat(display_long)|uniprotkb:Itm2b(gene name)|psi-mi:Itm2b(display_short)|uniprotkb:Immature BRI2(gene name synonym)|uniprotkb:Transmembrane protein BRI(gene name synonym)	psi-mi:ppia_rat(display_long)|uniprotkb:Ppia(gene name)|psi-mi:Ppia(display_short)|uniprotkb:Cyclophilin A(gene name synonym)|uniprotkb:Cyclosporin A-binding protein(gene name synonym)|uniprotkb:Rotamase A(gene name synonym)|uniprotkb:p1B15(gene name synonym)|uniprotkb:p31(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Martins et al. (2018)	imex:IM-28469|pubmed:29476059	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26438079|imex:IM-28469-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSRNOG00000016271(gene)|ensembl:ENSRNOT00000023037(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001540"(amyloid-beta binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0010008"(endosome membrane)|go:"GO:0030660"(Golgi-associated vesicle membrane)|go:"GO:0031301"(integral component of organelle membrane)|go:"GO:0042985"(negative regulation of amyloid precursor protein biosynthetic process)|interpro:IPR007084(BRICHOS)|interpro:IPR040145|mint:Q5XIE8|refseq:NP_001006964.1|rgd:620727	rgd:3372|refseq:NP_058797.1|refseq:XP_006250863.1|ensembl:ENSRNOG00000027864(gene)|ensembl:ENSRNOG00000055068(gene)|ensembl:ENSRNOT00000088798(transcript)|ensembl:ENSRNOT00000091873(transcript)|go:"GO:0000187"(obsolete activation of MAPK activity)|go:"GO:0000413"(protein peptidyl-prolyl isomerization)|go:"GO:0001933"(negative regulation of protein phosphorylation)|go:"GO:0001934"(positive regulation of protein phosphorylation)|go:"GO:0003755"(peptidyl-prolyl cis-trans isomerase activity)|go:"GO:0005178"(integrin binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006457"(protein folding)|go:"GO:0006469"(negative regulation of protein kinase activity)|go:"GO:0006915"(apoptotic process)|go:"GO:0016018"(cyclosporin A binding)|go:"GO:0030168"(platelet activation)|go:"GO:0030182"(neuron differentiation)|go:"GO:0030593"(neutrophil chemotaxis)|go:"GO:0030595"(leukocyte chemotaxis)|go:"GO:0032148"(activation of protein kinase B activity)|go:"GO:0032515"(negative regulation of phosphoprotein phosphatase activity)|go:"GO:0032873"(negative regulation of stress-activated MAPK cascade)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034389"(lipid droplet organization)|go:"GO:0034599"(cellular response to oxidative stress)|go:"GO:0035307"(positive regulation of protein dephosphorylation)|go:"GO:0042118"(endothelial cell activation)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0045069"(regulation of viral genome replication)|go:"GO:0045070"(positive regulation of viral genome replication)|go:"GO:0050714"(positive regulation of protein secretion)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|go:"GO:0060352"(cell adhesion molecule production)|go:"GO:0061944"(negative regulation of protein K48-linked ubiquitination)|go:"GO:0070527"(platelet aggregation)|go:"GO:1902176"(negative regulation of oxidative stress-induced intrinsic apoptotic signaling pathway)|go:"GO:1903901"(negative regulation of viral life cycle)|go:"GO:1904399"(heparan sulfate binding)|go:"GO:2001233"(regulation of apoptotic signaling pathway)|interpro:IPR002130(Peptidyl-prolyl cis-trans isomerase, cyclophilin-type)|interpro:IPR020892|interpro:IPR024936|interpro:IPR029000|mint:P10111|reactome:R-RNO-210991|reactome:R-RNO-6798695	-	-	-	figure legend:ST1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10116(rat-brain-cerebellum)|taxid:10116(Rattus norvegicus)	-	2020/10/30	2020/10/30	rogid:DtE+ZXAZKdCMvUW5K+jXQ5bH07M10116	rogid:7CdtHNtojvyM9dedEXrCGYIScxg10116	rigid:OaXQ9NA25fwCWxejPU3Ao9q5j/E	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q5XIE8	uniprotkb:P13596	intact:EBI-15348306|ensembl:ENSRNOP00000023037	intact:EBI-916499	psi-mi:itm2b_rat(display_long)|uniprotkb:Itm2b(gene name)|psi-mi:Itm2b(display_short)|uniprotkb:Immature BRI2(gene name synonym)|uniprotkb:Transmembrane protein BRI(gene name synonym)	psi-mi:ncam1_rat(display_long)|uniprotkb:Ncam1(gene name)|psi-mi:Ncam1(display_short)|uniprotkb:Ncam(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Martins et al. (2018)	imex:IM-28469|pubmed:29476059	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26438079|imex:IM-28469-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSRNOG00000016271(gene)|ensembl:ENSRNOT00000023037(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001540"(amyloid-beta binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0010008"(endosome membrane)|go:"GO:0030660"(Golgi-associated vesicle membrane)|go:"GO:0031301"(integral component of organelle membrane)|go:"GO:0042985"(negative regulation of amyloid precursor protein biosynthetic process)|interpro:IPR007084(BRICHOS)|interpro:IPR040145|mint:Q5XIE8|refseq:NP_001006964.1|rgd:620727	rgd:67378|interpro:IPR003599(Immunoglobulin subtype)|go:"GO:0001928"(regulation of exocyst assembly)|go:"GO:0005104"(fibroblast growth factor receptor binding)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0007155"(cell adhesion)|go:"GO:0007166"(cell surface receptor signaling pathway)|go:"GO:0007413"(axonal fasciculation)|go:"GO:0007420"(brain development)|go:"GO:0007568"(aging)|go:"GO:0007611"(learning or memory)|go:"GO:0008092"(cytoskeletal protein binding)|go:"GO:0008201"(heparin binding)|go:"GO:0009897"(external side of plasma membrane)|go:"GO:0009986"(cell surface)|go:"GO:0010035"(response to inorganic substance)|go:"GO:0010288"(response to lead ion)|go:"GO:0014012"(peripheral nervous system axon regeneration)|go:"GO:0014823"(response to activity)|go:"GO:0016338"(calcium-independent cell-cell adhesion via plasma membrane cell-adhesion molecules)|go:"GO:0019902"(phosphatase binding)|go:"GO:0021794"(thalamus development)|go:"GO:0030275"(LRR domain binding)|go:"GO:0030424"(axon)|go:"GO:0030426"(growth cone)|go:"GO:0031100"(animal organ regeneration)|go:"GO:0031175"(neuron projection development)|go:"GO:0033555"(multicellular organismal response to stress)|go:"GO:0034109"(homotypic cell-cell adhesion)|go:"GO:0042220"(response to cocaine)|go:"GO:0042493"|go:"GO:0043005"(neuron projection)|go:"GO:0043025"(neuronal cell body)|go:"GO:0048666"(neuron development)|go:"GO:0050804"(modulation of chemical synaptic transmission)|go:"GO:0050850"(positive regulation of calcium-mediated signaling)|go:"GO:0051930"(regulation of sensory perception of pain)|go:"GO:0060045"(positive regulation of cardiac muscle cell proliferation)|go:"GO:0060548"(negative regulation of cell death)|go:"GO:0071219"(cellular response to molecule of bacterial origin)|go:"GO:0071241"(cellular response to inorganic substance)|go:"GO:0071679"(commissural neuron axon guidance)|go:"GO:0098685"(Schaffer collateral - CA1 synapse)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099055"(integral component of postsynaptic membrane)|go:"GO:0099056"(integral component of presynaptic membrane)|go:"GO:2001260"(regulation of semaphorin-plexin signaling pathway)|rcsb pdb:1EPF|rcsb pdb:1LWR|rcsb pdb:1QZ1|reactome:R-RNO-375165|reactome:R-RNO-419037|reactome:R-RNO-445144|reactome:R-RNO-5673001|refseq:NP_113709.1|interpro:IPR003961(Fibronectin, type III)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR013098(Immunoglobulin I-set)|interpro:IPR003598(Immunoglobulin subtype 2)|interpro:IPR009138(Neural cell adhesion)|mint:P13596|interpro:IPR033019|interpro:IPR036116|interpro:IPR036179	-	-	-	figure legend:ST1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10116(rat-brain-cerebellum)|taxid:10116(Rattus norvegicus)	-	2020/10/30	2020/10/30	rogid:DtE+ZXAZKdCMvUW5K+jXQ5bH07M10116	rogid:QM7RSMedN9uQfR5L0S/24RL15WM10116	rigid:OaXQ9NA25fwCWxejPU3Ao9q5j/E	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q5XIE8	uniprotkb:Q00566	intact:EBI-15348306|ensembl:ENSRNOP00000023037	intact:EBI-9396907|uniprotkb:Q09HV7|uniprotkb:Q09HV8	psi-mi:itm2b_rat(display_long)|uniprotkb:Itm2b(gene name)|psi-mi:Itm2b(display_short)|uniprotkb:Immature BRI2(gene name synonym)|uniprotkb:Transmembrane protein BRI(gene name synonym)	psi-mi:mecp2_rat(display_long)|uniprotkb:Mecp2(gene name)|psi-mi:Mecp2(display_short)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Martins et al. (2018)	imex:IM-28469|pubmed:29476059	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26438079|imex:IM-28469-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSRNOG00000016271(gene)|ensembl:ENSRNOT00000023037(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001540"(amyloid-beta binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0010008"(endosome membrane)|go:"GO:0030660"(Golgi-associated vesicle membrane)|go:"GO:0031301"(integral component of organelle membrane)|go:"GO:0042985"(negative regulation of amyloid precursor protein biosynthetic process)|interpro:IPR007084(BRICHOS)|interpro:IPR040145|mint:Q5XIE8|refseq:NP_001006964.1|rgd:620727	rgd:3075|refseq:NP_073164.2|refseq:XP_006229629.1|mint:Q00566|dip:DIP-60875N|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000400"(four-way junction DNA binding)|go:"GO:0000785"(chromatin)|go:"GO:0000792"(heterochromatin)|go:"GO:0001662"(behavioral fear response)|go:"GO:0001666"(response to hypoxia)|go:"GO:0001964"(startle response)|go:"GO:0001976"(nervous system process involved in regulation of systemic arterial blood pressure)|go:"GO:0002087"(regulation of respiratory gaseous exchange by nervous system process)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0006020"(inositol metabolic process)|go:"GO:0006342"|go:"GO:0006349"(regulation of gene expression by genomic imprinting)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006541"(glutamine metabolic process)|go:"GO:0006576"(cellular biogenic amine metabolic process)|go:"GO:0007052"(mitotic spindle organization)|go:"GO:0007268"(chemical synaptic transmission)|go:"GO:0007416"(synapse assembly)|go:"GO:0007420"(brain development)|go:"GO:0007507"(heart development)|go:"GO:0007585"(respiratory gaseous exchange by respiratory system)|go:"GO:0007612"(learning)|go:"GO:0007613"(memory)|go:"GO:0007616"(long-term memory)|go:"GO:0008104"(protein localization)|go:"GO:0008211"(glucocorticoid metabolic process)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0008327"(methyl-CpG binding)|go:"GO:0008344"(adult locomotory behavior)|go:"GO:0008542"(visual learning)|go:"GO:0009791"(post-embryonic development)|go:"GO:0010212"(response to ionizing radiation)|go:"GO:0010288"(response to lead ion)|go:"GO:0010385"(double-stranded methylated DNA binding)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0010971"(positive regulation of G2/M transition of mitotic cell cycle)|go:"GO:0014003"(oligodendrocyte development)|go:"GO:0014070"(response to organic cyclic compound)|go:"GO:0016358"(dendrite development)|go:"GO:0016525"(negative regulation of angiogenesis)|go:"GO:0016571"(histone methylation)|go:"GO:0016573"(histone acetylation)|go:"GO:0019230"(proprioception)|go:"GO:0019233"(sensory perception of pain)|go:"GO:0019899"(enzyme binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0021510"(spinal cord development)|go:"GO:0021549"(cerebellum development)|go:"GO:0021591"(ventricular system development)|go:"GO:0021740"(principal sensory nucleus of trigeminal nerve development)|go:"GO:0021756"(striatum development)|go:"GO:0021766"(hippocampus development)|go:"GO:0021772"(olfactory bulb development)|go:"GO:0021794"(thalamus development)|go:"GO:0021987"(cerebral cortex development)|go:"GO:0030182"(neuron differentiation)|go:"GO:0031175"(neuron projection development)|go:"GO:0031490"(chromatin DNA binding)|go:"GO:0031915"(positive regulation of synaptic plasticity)|go:"GO:0032048"(cardiolipin metabolic process)|go:"GO:0032091"(negative regulation of protein binding)|go:"GO:0032355"(response to estradiol)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033555"(multicellular organismal response to stress)|go:"GO:0035176"(social behavior)|go:"GO:0035197"(siRNA binding)|go:"GO:0035865"(cellular response to potassium ion)|go:"GO:0040029"(regulation of gene expression, epigenetic)|go:"GO:0042220"(response to cocaine)|go:"GO:0042551"(neuron maturation)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0043537"(negative regulation of blood vessel endothelial cell migration)|go:"GO:0044030"(regulation of DNA methylation)|go:"GO:0045322"(unmethylated CpG binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046470"(phosphatidylcholine metabolic process)|go:"GO:0047485"(protein N-terminus binding)|go:"GO:0048167"(regulation of synaptic plasticity)|go:"GO:0048286"(lung alveolus development)|go:"GO:0048709"(oligodendrocyte differentiation)|go:"GO:0048712"(negative regulation of astrocyte differentiation)|go:"GO:0050807"(regulation of synapse organization)|go:"GO:0050884"(neuromuscular process controlling posture)|go:"GO:0050905"(neuromuscular process)|go:"GO:0051151"(negative regulation of smooth muscle cell differentiation)|go:"GO:0051570"(regulation of histone H3-K9 methylation)|go:"GO:0051707"(response to other organism)|go:"GO:0060079"(excitatory postsynaptic potential)|go:"GO:0060291"(long-term synaptic potentiation)|go:"GO:0060999"(positive regulation of dendritic spine development)|go:"GO:0061000"(negative regulation of dendritic spine development)|go:"GO:0071317"(cellular response to isoquinoline alkaloid)|go:"GO:0090063"(positive regulation of microtubule nucleation)|go:"GO:0098794"(postsynapse)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:1900114"(positive regulation of histone H3-K9 trimethylation)|go:"GO:1901953"(positive regulation of anterograde dense core granule transport)|go:"GO:1901956"(positive regulation of retrograde dense core granule transport)|go:"GO:1903860"(negative regulation of dendrite extension)|go:"GO:1903861"(positive regulation of dendrite extension)|go:"GO:1905492"(positive regulation of branching morphogenesis of a nerve)|go:"GO:1905643"(positive regulation of DNA methylation)|go:"GO:1990841"(promoter-specific chromatin binding)|go:"GO:2000635"(negative regulation of primary miRNA processing)|go:"GO:2000820"(negative regulation of transcription from RNA polymerase II promoter involved in smooth muscle cell differentiation)|interpro:IPR001739(Methyl-CpG DNA binding)|interpro:IPR016177(DNA-binding, integrase-type)|interpro:IPR017353(Methyl-CpG binding protein MeCP2)|reactome:R-RNO-9022692|go:"GO:0045892"(negative regulation of transcription, DNA-templated)	-	-	-	figure legend:ST1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10116(rat-brain-cerebellum)|taxid:10116(Rattus norvegicus)	-	2020/10/30	2020/10/30	rogid:DtE+ZXAZKdCMvUW5K+jXQ5bH07M10116	rogid:4SKidzlZWG9tVz73Ix/rFUJEcFw10116	rigid:OaXQ9NA25fwCWxejPU3Ao9q5j/E	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q5XIE8	uniprotkb:Q5XIN6	intact:EBI-15348306|ensembl:ENSRNOP00000023037	intact:EBI-26437014|ensembl:ENSRNOP00000022540	psi-mi:itm2b_rat(display_long)|uniprotkb:Itm2b(gene name)|psi-mi:Itm2b(display_short)|uniprotkb:Immature BRI2(gene name synonym)|uniprotkb:Transmembrane protein BRI(gene name synonym)	psi-mi:letm1_rat(display_long)|uniprotkb:Letm1(gene name)|psi-mi:Letm1(display_short)|uniprotkb:Leucine zipper-EF-hand-containing transmembrane protein 1(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Martins et al. (2018)	imex:IM-28469|pubmed:29476059	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26438079|imex:IM-28469-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSRNOG00000016271(gene)|ensembl:ENSRNOT00000023037(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001540"(amyloid-beta binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0010008"(endosome membrane)|go:"GO:0030660"(Golgi-associated vesicle membrane)|go:"GO:0031301"(integral component of organelle membrane)|go:"GO:0042985"(negative regulation of amyloid precursor protein biosynthetic process)|interpro:IPR007084(BRICHOS)|interpro:IPR040145|mint:Q5XIE8|refseq:NP_001006964.1|rgd:620727	ensembl:ENSRNOG00000016427(gene)|ensembl:ENSRNOT00000022540(transcript)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0006851"(mitochondrial calcium ion transmembrane transport)|go:"GO:0006875"(cellular metal ion homeostasis)|go:"GO:0015369"("calcium:proton antiporter activity")|go:"GO:0016021"(integral component of membrane)|go:"GO:0034214"(protein hexamerization)|go:"GO:0043022"(ribosome binding)|go:"GO:0046872"(metal ion binding)|go:"GO:0051260"(protein homooligomerization)|go:"GO:0051560"(mitochondrial calcium ion homeostasis)|go:"GO:0051562"(negative regulation of mitochondrial calcium ion concentration)|go:"GO:0099093"(calcium export from the mitochondrion)|go:"GO:1900069"(regulation of cellular hyperosmotic salinity response)|interpro:IPR011685(LETM1-like)|interpro:IPR011992(EF-Hand type)|interpro:IPR018247|interpro:IPR033122|interpro:IPR044202|mint:Q5XIN6|reactome:R-RNO-9013408|go:"GO:0042407"(cristae formation)|refseq:NP_001005884.1|rgd:1359678	-	-	-	figure legend:ST1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10116(rat-brain-cerebellum)|taxid:10116(Rattus norvegicus)	-	2020/10/30	2020/10/30	rogid:DtE+ZXAZKdCMvUW5K+jXQ5bH07M10116	rogid:Bm6lSh1gRcu0py5celXeD2thMQI10116	rigid:OaXQ9NA25fwCWxejPU3Ao9q5j/E	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q5XIE8	uniprotkb:P70615	intact:EBI-15348306|ensembl:ENSRNOP00000023037	intact:EBI-26436980	psi-mi:itm2b_rat(display_long)|uniprotkb:Itm2b(gene name)|psi-mi:Itm2b(display_short)|uniprotkb:Immature BRI2(gene name synonym)|uniprotkb:Transmembrane protein BRI(gene name synonym)	psi-mi:lmnb1_rat(display_long)|uniprotkb:Lmnb1(gene name)|psi-mi:Lmnb1(display_short)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Martins et al. (2018)	imex:IM-28469|pubmed:29476059	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26438079|imex:IM-28469-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSRNOG00000016271(gene)|ensembl:ENSRNOT00000023037(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001540"(amyloid-beta binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0010008"(endosome membrane)|go:"GO:0030660"(Golgi-associated vesicle membrane)|go:"GO:0031301"(integral component of organelle membrane)|go:"GO:0042985"(negative regulation of amyloid precursor protein biosynthetic process)|interpro:IPR007084(BRICHOS)|interpro:IPR040145|mint:Q5XIE8|refseq:NP_001006964.1|rgd:620727	go:"GO:0005638"(lamin filament)|go:"GO:0005652"(nuclear lamina)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006915"(apoptotic process)|go:"GO:0016363"(nuclear matrix)|go:"GO:0022008"(neurogenesis)|go:"GO:0031965"(nuclear membrane)|go:"GO:0042493"|go:"GO:0043274"(phospholipase binding)|go:"GO:0046677"(response to antibiotic)|go:"GO:0071386"(cellular response to corticosterone stimulus)|go:"GO:0071407"(cellular response to organic cyclic compound)|go:"GO:1904609"(cellular response to monosodium L-glutamate)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|reactome:R-RNO-2559584|reactome:R-RNO-352238|reactome:R-RNO-4419969|reactome:R-RNO-9013405|go:"GO:0005637"(nuclear inner membrane)|reactome:R-RNO-9035034|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005635"(nuclear envelope)|mint:P70615|refseq:NP_446357.1|interpro:IPR018039|interpro:IPR039008|interpro:IPR001322(Intermediate filament, C-terminal)|interpro:IPR036415|rgd:620522	-	-	-	figure legend:ST1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10116(rat-brain-cerebellum)|taxid:10116(Rattus norvegicus)	-	2020/10/30	2020/10/30	rogid:DtE+ZXAZKdCMvUW5K+jXQ5bH07M10116	rogid:Dd1grRaRWgqK8noPfIxgtO80nTU10116	rigid:OaXQ9NA25fwCWxejPU3Ao9q5j/E	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q5XIE8	uniprotkb:Q9WV63	intact:EBI-15348306|ensembl:ENSRNOP00000023037	intact:EBI-8848319|uniprotkb:Q5BJW1	psi-mi:itm2b_rat(display_long)|uniprotkb:Itm2b(gene name)|psi-mi:Itm2b(display_short)|uniprotkb:Immature BRI2(gene name synonym)|uniprotkb:Transmembrane protein BRI(gene name synonym)	psi-mi:kif2a_rat(display_long)|uniprotkb:Kif2a(gene name)|psi-mi:Kif2a(display_short)|uniprotkb:Kif2(gene name synonym)|uniprotkb:Kinesin-2(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Martins et al. (2018)	imex:IM-28469|pubmed:29476059	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26438079|imex:IM-28469-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSRNOG00000016271(gene)|ensembl:ENSRNOT00000023037(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001540"(amyloid-beta binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0010008"(endosome membrane)|go:"GO:0030660"(Golgi-associated vesicle membrane)|go:"GO:0031301"(integral component of organelle membrane)|go:"GO:0042985"(negative regulation of amyloid precursor protein biosynthetic process)|interpro:IPR007084(BRICHOS)|interpro:IPR040145|mint:Q5XIE8|refseq:NP_001006964.1|rgd:620727	mint:Q9WV63|interpro:IPR019821|interpro:IPR001752(Kinesin, motor region)|interpro:IPR027417|rgd:70974|interpro:IPR027640|interpro:IPR036961|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0000922"(spindle pole)|go:"GO:0003777"(microtubule motor activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005814"(centriole)|go:"GO:0005819"(spindle)|go:"GO:0005871"(kinesin complex)|go:"GO:0005874"(microtubule)|go:"GO:0007018"(microtubule-based movement)|go:"GO:0007052"(mitotic spindle organization)|go:"GO:0007399"(nervous system development)|go:"GO:0008017"(microtubule binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030154"(cell differentiation)|go:"GO:0030334"(regulation of cell migration)|go:"GO:0051301"(cell division)|go:"GO:0090307"(mitotic spindle assembly)|go:"GO:0097228"(sperm principal piece)|go:"GO:0120103"(centriolar subdistal appendage)|go:"GO:1990939"|reactome:R-RNO-141444|reactome:R-RNO-2132295|reactome:R-RNO-2467813|reactome:R-RNO-2500257|reactome:R-RNO-5663220|reactome:R-RNO-6811434|reactome:R-RNO-68877|reactome:R-RNO-9648025|reactome:R-RNO-983189	-	-	-	figure legend:ST1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10116(rat-brain-cerebellum)|taxid:10116(Rattus norvegicus)	-	2020/10/30	2020/10/30	rogid:DtE+ZXAZKdCMvUW5K+jXQ5bH07M10116	rogid:b7toIbVAaXCY8546ZyQ2KqTXhUI10116	rigid:OaXQ9NA25fwCWxejPU3Ao9q5j/E	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q5XIE8	uniprotkb:P41565	intact:EBI-15348306|ensembl:ENSRNOP00000023037	intact:EBI-1216916|uniprotkb:P70577	psi-mi:itm2b_rat(display_long)|uniprotkb:Itm2b(gene name)|psi-mi:Itm2b(display_short)|uniprotkb:Immature BRI2(gene name synonym)|uniprotkb:Transmembrane protein BRI(gene name synonym)	psi-mi:idhg1_rat(display_long)|uniprotkb:Idh3g(gene name)|psi-mi:Idh3g(display_short)|uniprotkb:Isocitric dehydrogenase subunit gamma(gene name synonym)|uniprotkb:"NAD(+)-specific ICDH subunit gamma"(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Martins et al. (2018)	imex:IM-28469|pubmed:29476059	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26438079|imex:IM-28469-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSRNOG00000016271(gene)|ensembl:ENSRNOT00000023037(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001540"(amyloid-beta binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0010008"(endosome membrane)|go:"GO:0030660"(Golgi-associated vesicle membrane)|go:"GO:0031301"(integral component of organelle membrane)|go:"GO:0042985"(negative regulation of amyloid precursor protein biosynthetic process)|interpro:IPR007084(BRICHOS)|interpro:IPR040145|mint:Q5XIE8|refseq:NP_001006964.1|rgd:620727	rgd:2863|interpro:IPR019818|interpro:IPR004434(Isocitrate dehydrogenase NAD-dependent, mitochondrial)|interpro:IPR024084|go:"GO:0000287"(magnesium ion binding)|go:"GO:0004449"("isocitrate dehydrogenase (NAD+) activity")|go:"GO:0005524"(ATP binding)|go:"GO:0005739"(mitochondrion)|go:"GO:0005962"("mitochondrial isocitrate dehydrogenase complex (NAD+)")|go:"GO:0006099"(tricarboxylic acid cycle)|go:"GO:0006102"(isocitrate metabolic process)|go:"GO:0006103"(2-oxoglutarate metabolic process)|go:"GO:0006734"(NADH metabolic process)|go:"GO:0045926"(negative regulation of growth)|go:"GO:0051287"(NAD binding)|reactome:R-RNO-71403|mint:P41565	-	-	-	figure legend:ST1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10116(rat-brain-cerebellum)|taxid:10116(Rattus norvegicus)	-	2020/10/30	2020/10/30	rogid:DtE+ZXAZKdCMvUW5K+jXQ5bH07M10116	rogid:C9m7ObsbAFiiYc7p+4A3NJHrjDA10116	rigid:OaXQ9NA25fwCWxejPU3Ao9q5j/E	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q5XIE8	uniprotkb:Q7TP98	intact:EBI-15348306|ensembl:ENSRNOP00000023037	intact:EBI-16220263	psi-mi:itm2b_rat(display_long)|uniprotkb:Itm2b(gene name)|psi-mi:Itm2b(display_short)|uniprotkb:Immature BRI2(gene name synonym)|uniprotkb:Transmembrane protein BRI(gene name synonym)	psi-mi:ilf2_rat(display_long)|uniprotkb:Ilf2(gene name)|psi-mi:Ilf2(display_short)|uniprotkb:Liver regeneration-related protein LRRG031(gene name synonym)|uniprotkb:Ab1-143(orf name)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Martins et al. (2018)	imex:IM-28469|pubmed:29476059	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26438079|imex:IM-28469-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSRNOG00000016271(gene)|ensembl:ENSRNOT00000023037(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001540"(amyloid-beta binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0010008"(endosome membrane)|go:"GO:0030660"(Golgi-associated vesicle membrane)|go:"GO:0031301"(integral component of organelle membrane)|go:"GO:0042985"(negative regulation of amyloid precursor protein biosynthetic process)|interpro:IPR007084(BRICHOS)|interpro:IPR040145|mint:Q5XIE8|refseq:NP_001006964.1|rgd:620727	go:"GO:0003677"(DNA binding)|go:"GO:0003725"(double-stranded RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:1990904"(ribonucleoprotein complex)|reactome:R-RNO-6798695|mint:Q7TP98|rgd:1305734|refseq:NP_001041351.1|interpro:IPR006561(DZF)|interpro:IPR043519	-	-	-	figure legend:ST1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10116(rat-brain-cerebellum)|taxid:10116(Rattus norvegicus)	-	2020/10/30	2020/10/30	rogid:DtE+ZXAZKdCMvUW5K+jXQ5bH07M10116	rogid:BW4MWHUtRRNuY5k06KuWpsWoAzE10116	rigid:OaXQ9NA25fwCWxejPU3Ao9q5j/E	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q5XIE8	uniprotkb:Q63269	intact:EBI-15348306|ensembl:ENSRNOP00000023037	intact:EBI-9212786	psi-mi:itm2b_rat(display_long)|uniprotkb:Itm2b(gene name)|psi-mi:Itm2b(display_short)|uniprotkb:Immature BRI2(gene name synonym)|uniprotkb:Transmembrane protein BRI(gene name synonym)	psi-mi:itpr3_rat(display_long)|uniprotkb:Itpr3(gene name)|psi-mi:Itpr3(display_short)|uniprotkb:IP3 receptor isoform 3(gene name synonym)|uniprotkb:Type 3 inositol 1,4,5-trisphosphate receptor(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Martins et al. (2018)	imex:IM-28469|pubmed:29476059	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26438079|imex:IM-28469-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSRNOG00000016271(gene)|ensembl:ENSRNOT00000023037(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001540"(amyloid-beta binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0010008"(endosome membrane)|go:"GO:0030660"(Golgi-associated vesicle membrane)|go:"GO:0031301"(integral component of organelle membrane)|go:"GO:0042985"(negative regulation of amyloid precursor protein biosynthetic process)|interpro:IPR007084(BRICHOS)|interpro:IPR040145|mint:Q5XIE8|refseq:NP_001006964.1|rgd:620727	rgd:2934|refseq:NP_037270.1|interpro:IPR000699(Intracellular calcium-release channel)|interpro:IPR014821(Inositol 1,4,5-trisphosphate/ryanodine receptor)|interpro:IPR000493(Inositol 1,4,5-trisphosphate-binding protein receptor)|interpro:IPR005821(Ion transport)|interpro:IPR016093(MIR motif)|interpro:IPR013662(RyR and IP3R Homology associated)|mint:Q63269|go:"GO:0000822"(inositol hexakisphosphate binding)|go:"GO:0005220"(inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005634"(nucleus)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005640"(nuclear outer membrane)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0005903"(brush border)|go:"GO:0006816"(calcium ion transport)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0007204"(positive regulation of cytosolic calcium ion concentration)|go:"GO:0007613"(memory)|go:"GO:0015085"(calcium ion transmembrane transporter activity)|go:"GO:0015278"(calcium-release channel activity)|go:"GO:0016529"(sarcoplasmic reticulum)|go:"GO:0030176"(integral component of endoplasmic reticulum membrane)|go:"GO:0030425"(dendrite)|go:"GO:0030659"(cytoplasmic vesicle membrane)|go:"GO:0030667"(secretory granule membrane)|go:"GO:0035091"(phosphatidylinositol binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043209"(myelin sheath)|go:"GO:0043235"(receptor complex)|go:"GO:0043533"(inositol 1,3,4,5 tetrakisphosphate binding)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045177"(apical part of cell)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0050913"(sensory perception of bitter taste)|go:"GO:0050916"(sensory perception of sweet taste)|go:"GO:0050917"(sensory perception of umami taste)|go:"GO:0051209"(release of sequestered calcium ion into cytosol)|go:"GO:0051592"(response to calcium ion)|go:"GO:0060291"(long-term synaptic potentiation)|go:"GO:0060402"(calcium ion transport into cytosol)|go:"GO:0070679"(inositol 1,4,5 trisphosphate binding)|go:"GO:0071320"(cellular response to cAMP)|go:"GO:0098793"(presynapse)|reactome:R-RNO-114508|reactome:R-RNO-139853|reactome:R-RNO-381676|reactome:R-RNO-5578775|reactome:R-RNO-983695|interpro:IPR035910|interpro:IPR036300	-	-	-	figure legend:ST1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10116(rat-brain-cerebellum)|taxid:10116(Rattus norvegicus)	-	2020/10/30	2020/10/30	rogid:DtE+ZXAZKdCMvUW5K+jXQ5bH07M10116	rogid:oRMNVKgAZmFh2eZEcEBXUUvMK7o10116	rigid:OaXQ9NA25fwCWxejPU3Ao9q5j/E	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q5XIE8	uniprotkb:Q9Z2X5	intact:EBI-15348306|ensembl:ENSRNOP00000023037	intact:EBI-920352|ensembl:ENSRNOP00000027428	psi-mi:itm2b_rat(display_long)|uniprotkb:Itm2b(gene name)|psi-mi:Itm2b(display_short)|uniprotkb:Immature BRI2(gene name synonym)|uniprotkb:Transmembrane protein BRI(gene name synonym)	psi-mi:home3_rat(display_long)|uniprotkb:Homer3(gene name)|psi-mi:Homer3(display_short)|uniprotkb:Vesl3(gene name synonym)|uniprotkb:VASP/Ena-related gene up-regulated during seizure and LTP 3(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Martins et al. (2018)	imex:IM-28469|pubmed:29476059	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26438079|imex:IM-28469-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSRNOG00000016271(gene)|ensembl:ENSRNOT00000023037(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001540"(amyloid-beta binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0010008"(endosome membrane)|go:"GO:0030660"(Golgi-associated vesicle membrane)|go:"GO:0031301"(integral component of organelle membrane)|go:"GO:0042985"(negative regulation of amyloid precursor protein biosynthetic process)|interpro:IPR007084(BRICHOS)|interpro:IPR040145|mint:Q5XIE8|refseq:NP_001006964.1|rgd:620727	rgd:620706|refseq:NP_445762.1|refseq:XP_006252953.1|ensembl:ENSRNOG00000020229(gene)|ensembl:ENSRNOT00000027428(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0007216"(G protein-coupled glutamate receptor signaling pathway)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0014069"(postsynaptic density)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030425"(dendrite)|go:"GO:0032703"(negative regulation of interleukin-2 production)|go:"GO:0035256"(G protein-coupled glutamate receptor binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0045178"(basal part of cell)|go:"GO:0070885"(negative regulation of calcineurin-NFAT signaling cascade)|go:"GO:0098962"(regulation of postsynaptic neurotransmitter receptor activity)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:2001256"(regulation of store-operated calcium entry)|interpro:IPR000697(EVH1)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR044100|mint:Q9Z2X5|reactome:R-RNO-6794361	-	-	-	figure legend:ST1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10116(rat-brain-cerebellum)|taxid:10116(Rattus norvegicus)	-	2020/10/30	2020/10/30	rogid:DtE+ZXAZKdCMvUW5K+jXQ5bH07M10116	rogid:pJzod+zFtQHxU0N93UNrPzWttIU10116	rigid:OaXQ9NA25fwCWxejPU3Ao9q5j/E	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q5XIE8	uniprotkb:Q7TP47	intact:EBI-15348306|ensembl:ENSRNOP00000023037	intact:EBI-919386|ensembl:ENSRNOP00000048433	psi-mi:itm2b_rat(display_long)|uniprotkb:Itm2b(gene name)|psi-mi:Itm2b(display_short)|uniprotkb:Immature BRI2(gene name synonym)|uniprotkb:Transmembrane protein BRI(gene name synonym)	psi-mi:hnrpq_rat(display_long)|uniprotkb:Syncrip(gene name)|psi-mi:Syncrip(display_short)|uniprotkb:Hnrpq(gene name synonym)|uniprotkb:Ab2-339(orf name)|uniprotkb:Synaptotagmin-binding, cytoplasmic RNA-interacting protein(gene name synonym)|uniprotkb:Liver regeneration-related protein LRRG077(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Martins et al. (2018)	imex:IM-28469|pubmed:29476059	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26438079|imex:IM-28469-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSRNOG00000016271(gene)|ensembl:ENSRNOT00000023037(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001540"(amyloid-beta binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0010008"(endosome membrane)|go:"GO:0030660"(Golgi-associated vesicle membrane)|go:"GO:0031301"(integral component of organelle membrane)|go:"GO:0042985"(negative regulation of amyloid precursor protein biosynthetic process)|interpro:IPR007084(BRICHOS)|interpro:IPR040145|mint:Q5XIE8|refseq:NP_001006964.1|rgd:620727	rgd:1305683|refseq:NP_001041381.1|ensembl:ENSRNOG00000000204(gene)|ensembl:ENSRNOT00000041655(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0003730"(mRNA 3'-UTR binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0006397"(mRNA processing)|go:"GO:0007623"(circadian rhythm)|go:"GO:0008143"("poly(A) binding")|go:"GO:0008380"(RNA splicing)|go:"GO:0016020"(membrane)|go:"GO:0017148"(negative regulation of translation)|go:"GO:0043025"(neuronal cell body)|go:"GO:0045727"(positive regulation of translation)|go:"GO:0048027"(mRNA 5'-UTR binding)|go:"GO:0070934"(CRD-mediated mRNA stabilization)|go:"GO:0070937"(CRD-mediated mRNA stability complex)|go:"GO:0071013"(catalytic step 2 spliceosome)|go:"GO:0071204"(histone pre-mRNA 3'end processing complex)|go:"GO:0071346"(cellular response to interferon-gamma)|go:"GO:0090367"(negative regulation of mRNA modification)|go:"GO:0097452"(GAIT complex)|go:"GO:1990635"(proximal dendrite)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR006535(HnRNP R and Q splicing factor)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR034544|interpro:IPR034548|interpro:IPR035979|mint:Q7TP47	-	-	-	figure legend:ST1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10116(rat-brain-cerebellum)|taxid:10116(Rattus norvegicus)	-	2020/10/30	2020/10/30	rogid:DtE+ZXAZKdCMvUW5K+jXQ5bH07M10116	rogid:AETEMoY8iTxnVf1mtSgs1TKDwwk10116	rigid:OaXQ9NA25fwCWxejPU3Ao9q5j/E	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q5XIE8	uniprotkb:Q62826	intact:EBI-15348306|ensembl:ENSRNOP00000023037	intact:EBI-16220240|uniprotkb:Q5M815	psi-mi:itm2b_rat(display_long)|uniprotkb:Itm2b(gene name)|psi-mi:Itm2b(display_short)|uniprotkb:Immature BRI2(gene name synonym)|uniprotkb:Transmembrane protein BRI(gene name synonym)	psi-mi:hnrpm_rat(display_long)|uniprotkb:Hnrnpm(gene name)|psi-mi:Hnrnpm(display_short)|uniprotkb:Hnrpm(gene name synonym)|uniprotkb:M4 protein(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Martins et al. (2018)	imex:IM-28469|pubmed:29476059	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26438079|imex:IM-28469-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSRNOG00000016271(gene)|ensembl:ENSRNOT00000023037(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001540"(amyloid-beta binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0010008"(endosome membrane)|go:"GO:0030660"(Golgi-associated vesicle membrane)|go:"GO:0031301"(integral component of organelle membrane)|go:"GO:0042985"(negative regulation of amyloid precursor protein biosynthetic process)|interpro:IPR007084(BRICHOS)|interpro:IPR040145|mint:Q5XIE8|refseq:NP_001006964.1|rgd:620727	go:"GO:0000380"(alternative mRNA splicing, via spliceosome)|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005681"(spliceosomal complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0009986"(cell surface)|go:"GO:0016363"(nuclear matrix)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0042382"(paraspeckles)|go:"GO:0048306"(calcium-dependent protein binding)|go:"GO:0071013"(catalytic step 2 spliceosome)|go:"GO:0071014"(post-mRNA release spliceosomal complex)|go:"GO:0071222"(cellular response to lipopolysaccharide)|go:"GO:1900182"(positive regulation of protein localization to nucleus)|go:"GO:1904591"(positive regulation of protein import)|go:"GO:1990405"(protein antigen binding)|go:"GO:1990831"(cellular response to carcinoembryonic antigen)|go:"GO:1990904"(ribonucleoprotein complex)|go:"GO:2000815"(regulation of mRNA stability involved in response to oxidative stress)|reactome:R-RNO-6803529|reactome:R-RNO-72163|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|mint:Q62826|rgd:620369|refseq:NP_001103381.1|refseq:NP_446328.2|interpro:IPR024667|interpro:IPR024666|interpro:IPR034990|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR035979	-	-	-	figure legend:ST1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10116(rat-brain-cerebellum)|taxid:10116(Rattus norvegicus)	-	2020/10/30	2020/10/30	rogid:DtE+ZXAZKdCMvUW5K+jXQ5bH07M10116	rogid:f58dejJ2soG3/XwhRltPNpIxJas10116	rigid:OaXQ9NA25fwCWxejPU3Ao9q5j/E	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q5XIE8	uniprotkb:P11517	intact:EBI-15348306|ensembl:ENSRNOP00000023037	intact:EBI-6122082|ensembl:ENSRNOP00000069937|ensembl:ENSRNOP00000071528|ensembl:ENSRNOP00000072853	psi-mi:itm2b_rat(display_long)|uniprotkb:Itm2b(gene name)|psi-mi:Itm2b(display_short)|uniprotkb:Immature BRI2(gene name synonym)|uniprotkb:Transmembrane protein BRI(gene name synonym)	psi-mi:hbb2_rat(display_long)|uniprotkb:Beta-2-globin(gene name synonym)|uniprotkb:Hemoglobin beta chain, minor-form(gene name synonym)|uniprotkb:Hemoglobin beta-2 chain(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Martins et al. (2018)	imex:IM-28469|pubmed:29476059	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26438079|imex:IM-28469-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSRNOG00000016271(gene)|ensembl:ENSRNOT00000023037(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001540"(amyloid-beta binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0010008"(endosome membrane)|go:"GO:0030660"(Golgi-associated vesicle membrane)|go:"GO:0031301"(integral component of organelle membrane)|go:"GO:0042985"(negative regulation of amyloid precursor protein biosynthetic process)|interpro:IPR007084(BRICHOS)|interpro:IPR040145|mint:Q5XIE8|refseq:NP_001006964.1|rgd:620727	refseq:XP_008772023.1|refseq:NP_001104739.1|refseq:NP_001106694.1|refseq:XP_017458001.1|ensembl:ENSRNOG00000047098(gene)|ensembl:ENSRNOG00000054582(gene)|ensembl:ENSRNOG00000061299(gene)|ensembl:ENSRNOT00000089102(transcript)|ensembl:ENSRNOT00000090678(transcript)|ensembl:ENSRNOT00000090745(transcript)|go:"GO:0005344"(oxygen carrier activity)|go:"GO:0005833"(hemoglobin complex)|go:"GO:0019825"(oxygen binding)|go:"GO:0020037"(heme binding)|go:"GO:0031721"(hemoglobin alpha binding)|go:"GO:0031838"(haptoglobin-hemoglobin complex)|go:"GO:0042744"(hydrogen peroxide catabolic process)|go:"GO:0043177"(organic acid binding)|go:"GO:0046872"(metal ion binding)|go:"GO:0098869"(cellular oxidant detoxification)|interpro:IPR000971(Globin, subset)|interpro:IPR002337(Haemoglobin, beta)|interpro:IPR009050(Globin-like)|interpro:IPR012292(Globin)|mint:P11517	-	-	-	figure legend:ST1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10116(rat-brain-cerebellum)|taxid:10116(Rattus norvegicus)	-	2020/10/30	2020/10/30	rogid:DtE+ZXAZKdCMvUW5K+jXQ5bH07M10116	rogid:6gxHjDfzE7hbndFkL2K9lSQ94eU10116	rigid:OaXQ9NA25fwCWxejPU3Ao9q5j/E	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q5XIE8	uniprotkb:P82471	intact:EBI-15348306|ensembl:ENSRNOP00000023037	intact:EBI-26436922	psi-mi:itm2b_rat(display_long)|uniprotkb:Itm2b(gene name)|psi-mi:Itm2b(display_short)|uniprotkb:Immature BRI2(gene name synonym)|uniprotkb:Transmembrane protein BRI(gene name synonym)	psi-mi:gnaq_rat(display_long)|uniprotkb:Gnaq(gene name)|psi-mi:Gnaq(display_short)|uniprotkb:Guanine nucleotide-binding protein alpha-q(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Martins et al. (2018)	imex:IM-28469|pubmed:29476059	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26438079|imex:IM-28469-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSRNOG00000016271(gene)|ensembl:ENSRNOT00000023037(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001540"(amyloid-beta binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0010008"(endosome membrane)|go:"GO:0030660"(Golgi-associated vesicle membrane)|go:"GO:0031301"(integral component of organelle membrane)|go:"GO:0042985"(negative regulation of amyloid precursor protein biosynthetic process)|interpro:IPR007084(BRICHOS)|interpro:IPR040145|mint:Q5XIE8|refseq:NP_001006964.1|rgd:620727	go:"GO:0001501"(skeletal system development)|go:"GO:0001508"(action potential)|go:"GO:0001664"(G protein-coupled receptor binding)|go:"GO:0003924"(GTPase activity)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0005834"(heterotrimeric G-protein complex)|go:"GO:0005886"(plasma membrane)|go:"GO:0005901"(caveola)|go:"GO:0006469"(negative regulation of protein kinase activity)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0007188"(adenylate cyclase-modulating G protein-coupled receptor signaling pathway)|go:"GO:0007189"(adenylate cyclase-activating G protein-coupled receptor signaling pathway)|go:"GO:0007200"(phospholipase C-activating G protein-coupled receptor signaling pathway)|go:"GO:0007202"(activation of phospholipase C activity)|go:"GO:0007215"(glutamate receptor signaling pathway)|go:"GO:0007507"(heart development)|go:"GO:0009791"(post-embryonic development)|go:"GO:0016020"(membrane)|go:"GO:0016322"(neuron remodeling)|go:"GO:0021884"(forebrain neuron development)|go:"GO:0030425"(dendrite)|go:"GO:0031683"(G-protein beta/gamma-subunit complex binding)|go:"GO:0031826"(type 2A serotonin receptor binding)|go:"GO:0031965"(nuclear membrane)|go:"GO:0042711"(maternal behavior)|go:"GO:0042733"(embryonic digit morphogenesis)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043267"(negative regulation of potassium ion transport)|go:"GO:0044297"(cell body)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045202"(synapse)|go:"GO:0045634"(regulation of melanocyte differentiation)|go:"GO:0046872"(metal ion binding)|go:"GO:0047391"(alkylglycerophosphoethanolamine phosphodiesterase activity)|go:"GO:0048066"(developmental pigmentation)|go:"GO:0048661"(positive regulation of smooth muscle cell proliferation)|go:"GO:0050821"(protein stabilization)|go:"GO:0060158"(phospholipase C-activating dopamine receptor signaling pathway)|reactome:R-RNO-112043|reactome:R-RNO-202040|reactome:R-RNO-399997|reactome:R-RNO-416476|reactome:R-RNO-418592|reactome:R-RNO-428930|reactome:R-RNO-434316|reactome:R-RNO-456926|go:"GO:0060828"(regulation of canonical Wnt signaling pathway)|mint:P82471|refseq:NP_112298.1|interpro:IPR000654(G-protein alpha subunit, group Q)|interpro:IPR001019("Guanine nucleotide binding protein (G-protein), alpha subunit")|interpro:IPR011025(G protein alpha subunit, helical insertion)|interpro:IPR027417|rgd:620770	-	-	-	figure legend:ST1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10116(rat-brain-cerebellum)|taxid:10116(Rattus norvegicus)	-	2020/10/30	2020/10/30	rogid:DtE+ZXAZKdCMvUW5K+jXQ5bH07M10116	rogid:HcK+uMZKOwSAwRYxneFl+Gfqpos10116	rigid:OaXQ9NA25fwCWxejPU3Ao9q5j/E	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q5XIE8	uniprotkb:B2GUZ5	intact:EBI-15348306|ensembl:ENSRNOP00000023037	intact:EBI-21998020|ensembl:ENSRNOP00000052868	psi-mi:itm2b_rat(display_long)|uniprotkb:Itm2b(gene name)|psi-mi:Itm2b(display_short)|uniprotkb:Immature BRI2(gene name synonym)|uniprotkb:Transmembrane protein BRI(gene name synonym)	psi-mi:caza1_rat(display_long)|uniprotkb:CapZ alpha-1(gene name synonym)|uniprotkb:Capza1(gene name)|psi-mi:Capza1(display_short)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Martins et al. (2018)	imex:IM-28469|pubmed:29476059	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26438079|imex:IM-28469-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSRNOG00000016271(gene)|ensembl:ENSRNOT00000023037(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001540"(amyloid-beta binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0010008"(endosome membrane)|go:"GO:0030660"(Golgi-associated vesicle membrane)|go:"GO:0031301"(integral component of organelle membrane)|go:"GO:0042985"(negative regulation of amyloid precursor protein biosynthetic process)|interpro:IPR007084(BRICHOS)|interpro:IPR040145|mint:Q5XIE8|refseq:NP_001006964.1|rgd:620727	rgd:1587438|refseq:NP_001103095.2|ensembl:ENSRNOG00000013538(gene)|ensembl:ENSRNOT00000056015(transcript)|go:"GO:0005903"(brush border)|go:"GO:0005911"(cell-cell junction)|go:"GO:0008290"(F-actin capping protein complex)|go:"GO:0016020"(membrane)|go:"GO:0030036"(actin cytoskeleton organization)|go:"GO:0030863"(cortical cytoskeleton)|go:"GO:0034329"(cell junction assembly)|go:"GO:0051015"(actin filament binding)|go:"GO:0051016"(barbed-end actin filament capping)|go:"GO:0071203"(WASH complex)|interpro:IPR002189(F-actin capping protein, alpha subunit)|interpro:IPR017865|interpro:IPR037282|interpro:IPR042276|interpro:IPR042489|mint:B2GUZ5|reactome:R-RNO-2132295|reactome:R-RNO-3371497|reactome:R-RNO-6807878|reactome:R-RNO-6811436|reactome:R-RNO-879415|reactome:R-RNO-983231	-	-	-	figure legend:ST1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10116(rat-brain-cerebellum)|taxid:10116(Rattus norvegicus)	-	2020/10/30	2020/10/30	rogid:DtE+ZXAZKdCMvUW5K+jXQ5bH07M10116	rogid:UPsnX1OJqUXRCsNROP94st+7nMA10116	rigid:OaXQ9NA25fwCWxejPU3Ao9q5j/E	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q5XIE8	uniprotkb:O35921	intact:EBI-15348306|ensembl:ENSRNOP00000023037	intact:EBI-26436896|uniprotkb:P97683	psi-mi:itm2b_rat(display_long)|uniprotkb:Itm2b(gene name)|psi-mi:Itm2b(display_short)|uniprotkb:Immature BRI2(gene name synonym)|uniprotkb:Transmembrane protein BRI(gene name synonym)	psi-mi:eaa4_rat(display_long)|uniprotkb:Slc1a6(gene name)|psi-mi:Slc1a6(display_short)|uniprotkb:Eaat4(gene name synonym)|uniprotkb:High-affinity neuronal glutamate transporter(gene name synonym)|uniprotkb:Sodium-dependent glutamate/aspartate transporter(gene name synonym)|uniprotkb:Solute carrier family 1 member 6(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Martins et al. (2018)	imex:IM-28469|pubmed:29476059	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26438079|imex:IM-28469-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSRNOG00000016271(gene)|ensembl:ENSRNOT00000023037(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001540"(amyloid-beta binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0010008"(endosome membrane)|go:"GO:0030660"(Golgi-associated vesicle membrane)|go:"GO:0031301"(integral component of organelle membrane)|go:"GO:0042985"(negative regulation of amyloid precursor protein biosynthetic process)|interpro:IPR007084(BRICHOS)|interpro:IPR040145|mint:Q5XIE8|refseq:NP_001006964.1|rgd:620727	go:"GO:0001504"(neurotransmitter uptake)|go:"GO:0005313"(L-glutamate transmembrane transporter activity)|go:"GO:0005314"(high-affinity glutamate transmembrane transporter activity)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0008509"(anion transmembrane transporter activity)|go:"GO:0015813"(L-glutamate transmembrane transport)|go:"GO:0016020"(membrane)|go:"GO:0042391"(regulation of membrane potential)|go:"GO:0046872"(metal ion binding)|go:"GO:0098688"(parallel fiber to Purkinje cell synapse)|go:"GO:0098712"(L-glutamate import across plasma membrane)|go:"GO:0098796"(membrane protein complex)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099055"(integral component of postsynaptic membrane)|go:"GO:0099056"(integral component of presynaptic membrane)|reactome:R-RNO-210500|reactome:R-RNO-425393|mint:O35921|refseq:NP_114454.1|interpro:IPR001991("Sodium:dicarboxylate symporter")|interpro:IPR018107|interpro:IPR036458|rgd:620340	-	-	-	figure legend:ST1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10116(rat-brain-cerebellum)|taxid:10116(Rattus norvegicus)	-	2020/10/30	2020/10/30	rogid:DtE+ZXAZKdCMvUW5K+jXQ5bH07M10116	rogid:O/0IUCwyqUzVk2IxgETAHWn+yWA10116	rigid:OaXQ9NA25fwCWxejPU3Ao9q5j/E	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q5XIE8	uniprotkb:B5DEH2	intact:EBI-15348306|ensembl:ENSRNOP00000023037	intact:EBI-6899638|ensembl:ENSRNOP00000018973	psi-mi:itm2b_rat(display_long)|uniprotkb:Itm2b(gene name)|psi-mi:Itm2b(display_short)|uniprotkb:Immature BRI2(gene name synonym)|uniprotkb:Transmembrane protein BRI(gene name synonym)	psi-mi:erln2_rat(display_long)|uniprotkb:Erlin2(gene name)|psi-mi:Erlin2(display_short)|uniprotkb:Spfh2(gene name synonym)|uniprotkb:Endoplasmic reticulum lipid raft-associated protein 2(gene name synonym)|uniprotkb:Stomatin-prohibitin-flotillin-HflC/K domain-containing protein 2(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Martins et al. (2018)	imex:IM-28469|pubmed:29476059	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26438079|imex:IM-28469-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSRNOG00000016271(gene)|ensembl:ENSRNOT00000023037(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001540"(amyloid-beta binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0010008"(endosome membrane)|go:"GO:0030660"(Golgi-associated vesicle membrane)|go:"GO:0031301"(integral component of organelle membrane)|go:"GO:0042985"(negative regulation of amyloid precursor protein biosynthetic process)|interpro:IPR007084(BRICHOS)|interpro:IPR040145|mint:Q5XIE8|refseq:NP_001006964.1|rgd:620727	refseq:XP_008769545.1|refseq:XP_008769546.1|go:"GO:0030433"(ubiquitin-dependent ERAD pathway)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032933"(SREBP signaling pathway)|go:"GO:0032991"(protein-containing complex)|go:"GO:0045121"(membrane raft)|go:"GO:0045541"(negative regulation of cholesterol biosynthetic process)|go:"GO:0045717"(negative regulation of fatty acid biosynthetic process)|interpro:IPR001107(Band 7 protein)|interpro:IPR033294|interpro:IPR036013|mint:B5DEH2|reactome:R-RNO-382556|ensembl:ENSRNOG00000013763(gene)|ensembl:ENSRNOT00000018973(transcript)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0008203"(cholesterol metabolic process)|go:"GO:0015485"(cholesterol binding)|go:"GO:0016021"(integral component of membrane)|refseq:NP_001099558.1|rgd:1309010	-	-	-	figure legend:ST1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10116(rat-brain-cerebellum)|taxid:10116(Rattus norvegicus)	-	2020/10/30	2020/10/30	rogid:DtE+ZXAZKdCMvUW5K+jXQ5bH07M10116	rogid:kM+VJSUenZBMGic+n66k8LHXWdo10116	rigid:OaXQ9NA25fwCWxejPU3Ao9q5j/E	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q5XIE8	uniprotkb:B0BND0	intact:EBI-15348306|ensembl:ENSRNOP00000023037	intact:EBI-26436874|ensembl:ENSRNOP00000013005	psi-mi:itm2b_rat(display_long)|uniprotkb:Itm2b(gene name)|psi-mi:Itm2b(display_short)|uniprotkb:Immature BRI2(gene name synonym)|uniprotkb:Transmembrane protein BRI(gene name synonym)	psi-mi:enpp6_rat(display_long)|uniprotkb:Enpp6(gene name)|psi-mi:Enpp6(display_short)|uniprotkb:Choline-specific glycerophosphodiester phosphodiesterase(gene name synonym)|uniprotkb:Ectonucleotide pyrophosphatase/phosphodiesterase family member 6(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Martins et al. (2018)	imex:IM-28469|pubmed:29476059	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26438079|imex:IM-28469-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSRNOG00000016271(gene)|ensembl:ENSRNOT00000023037(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001540"(amyloid-beta binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0010008"(endosome membrane)|go:"GO:0030660"(Golgi-associated vesicle membrane)|go:"GO:0031301"(integral component of organelle membrane)|go:"GO:0042985"(negative regulation of amyloid precursor protein biosynthetic process)|interpro:IPR007084(BRICHOS)|interpro:IPR040145|mint:Q5XIE8|refseq:NP_001006964.1|rgd:620727	ensembl:ENSRNOG00000009660(gene)|ensembl:ENSRNOT00000013005(transcript)|go:"GO:0005576"(extracellular region)|go:"GO:0005886"(plasma membrane)|go:"GO:0006629"(lipid metabolic process)|go:"GO:0008081"(phosphoric diester hydrolase activity)|go:"GO:0008889"(glycerophosphodiester phosphodiesterase activity)|go:"GO:0016042"(lipid catabolic process)|go:"GO:0019695"(choline metabolic process)|go:"GO:0031225"(anchored component of membrane)|go:"GO:0046872"(metal ion binding)|go:"GO:0047390"(glycerophosphocholine cholinephosphodiesterase activity)|interpro:IPR002591(Type I phosphodiesterase/nucleotide pyrophosphatase/phosphate transferase)|interpro:IPR017850(Alkaline-phosphatase-like, core domain)|interpro:IPR029889|mint:B0BND0|reactome:R-RNO-6814848|refseq:XP_006253218.1|rgd:1311645	-	-	-	figure legend:ST1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10116(rat-brain-cerebellum)|taxid:10116(Rattus norvegicus)	-	2020/10/30	2020/10/30	rogid:DtE+ZXAZKdCMvUW5K+jXQ5bH07M10116	rogid:+/iBpVT9zCR9URo1dMtqwFWlVl810116	rigid:OaXQ9NA25fwCWxejPU3Ao9q5j/E	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q5XIE8	uniprotkb:Q62951	intact:EBI-15348306|ensembl:ENSRNOP00000023037	intact:EBI-2255842	psi-mi:itm2b_rat(display_long)|uniprotkb:Itm2b(gene name)|psi-mi:Itm2b(display_short)|uniprotkb:Immature BRI2(gene name synonym)|uniprotkb:Transmembrane protein BRI(gene name synonym)	psi-mi:dpyl4_rat(display_long)|uniprotkb:Dpysl4(gene name)|psi-mi:Dpysl4(display_short)|uniprotkb:Crmp3(gene name synonym)|uniprotkb:Ulip4(gene name synonym)|uniprotkb:Collapsin response mediator protein 3(gene name synonym)|uniprotkb:UNC33-like phosphoprotein 4(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Martins et al. (2018)	imex:IM-28469|pubmed:29476059	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26438079|imex:IM-28469-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSRNOG00000016271(gene)|ensembl:ENSRNOT00000023037(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001540"(amyloid-beta binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0010008"(endosome membrane)|go:"GO:0030660"(Golgi-associated vesicle membrane)|go:"GO:0031301"(integral component of organelle membrane)|go:"GO:0042985"(negative regulation of amyloid precursor protein biosynthetic process)|interpro:IPR007084(BRICHOS)|interpro:IPR040145|mint:Q5XIE8|refseq:NP_001006964.1|rgd:620727	rgd:2409|refseq:NP_037065.1|interpro:IPR006680(Amidohydrolase 1)|interpro:IPR011778(D-hydantoinase)|interpro:IPR011059(Metal-dependent hydrolase, composite)|interpro:IPR030612|interpro:IPR032466|mint:Q62951|go:"GO:0005737"(cytoplasm)|go:"GO:0016810"("hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds")|go:"GO:0031005"(filamin binding)|go:"GO:0048666"(neuron development)|go:"GO:0051219"(phosphoprotein binding)|go:"GO:0070997"(neuron death)|go:"GO:0097485"(neuron projection guidance)|reactome:R-RNO-399956	-	-	-	figure legend:ST1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10116(rat-brain-cerebellum)|taxid:10116(Rattus norvegicus)	-	2020/10/30	2020/10/30	rogid:DtE+ZXAZKdCMvUW5K+jXQ5bH07M10116	rogid:ySgRvgBp8dBBZebavSjeW9O6MT010116	rigid:OaXQ9NA25fwCWxejPU3Ao9q5j/E	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q5XIE8	uniprotkb:Q6Q0N1	intact:EBI-15348306|ensembl:ENSRNOP00000023037	intact:EBI-26436850|ensembl:ENSRNOP00000021400	psi-mi:itm2b_rat(display_long)|uniprotkb:Itm2b(gene name)|psi-mi:Itm2b(display_short)|uniprotkb:Immature BRI2(gene name synonym)|uniprotkb:Transmembrane protein BRI(gene name synonym)	psi-mi:cndp2_rat(display_long)|uniprotkb:Cndp2(gene name)|psi-mi:Cndp2(display_short)|uniprotkb:CNDP dipeptidase 2(gene name synonym)|uniprotkb:Threonyl dipeptidase(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Martins et al. (2018)	imex:IM-28469|pubmed:29476059	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26438079|imex:IM-28469-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSRNOG00000016271(gene)|ensembl:ENSRNOT00000023037(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001540"(amyloid-beta binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0010008"(endosome membrane)|go:"GO:0030660"(Golgi-associated vesicle membrane)|go:"GO:0031301"(integral component of organelle membrane)|go:"GO:0042985"(negative regulation of amyloid precursor protein biosynthetic process)|interpro:IPR007084(BRICHOS)|interpro:IPR040145|mint:Q5XIE8|refseq:NP_001006964.1|rgd:620727	go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006508"(proteolysis)|go:"GO:0008233"(peptidase activity)|go:"GO:0016805"(dipeptidase activity)|go:"GO:0046872"(metal ion binding)|go:"GO:0070573"(metallodipeptidase activity)|go:"GO:0103046"(alanylglutamate dipeptidase activity)|interpro:IPR001261(ArgE/DapE/ACY1/CPG2/YscS, conserved site)|interpro:IPR002933(Peptidase M20)|interpro:IPR011650(Peptidase M20, dimerisation)|interpro:IPR017153(Glutathione degradosome, DUG1)|mint:Q6Q0N1|reactome:R-RNO-174403|ensembl:ENSRNOG00000015591(gene)|ensembl:ENSRNOT00000021400(transcript)|go:"GO:0004180"(carboxypeptidase activity)|refseq:NP_001010920.1|refseq:XP_006255061.1|rgd:1305827	-	-	-	figure legend:ST1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10116(rat-brain-cerebellum)|taxid:10116(Rattus norvegicus)	-	2020/10/30	2020/10/30	rogid:DtE+ZXAZKdCMvUW5K+jXQ5bH07M10116	rogid:Mhy3NFvdFcAA4p+LYfLkCMXJkrk10116	rigid:OaXQ9NA25fwCWxejPU3Ao9q5j/E	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q5XIE8	uniprotkb:P11240	intact:EBI-15348306|ensembl:ENSRNOP00000023037	intact:EBI-916313|ensembl:ENSRNOP00000025525	psi-mi:itm2b_rat(display_long)|uniprotkb:Itm2b(gene name)|psi-mi:Itm2b(display_short)|uniprotkb:Immature BRI2(gene name synonym)|uniprotkb:Transmembrane protein BRI(gene name synonym)	psi-mi:cox5a_rat(display_long)|uniprotkb:Cox5a(gene name)|psi-mi:Cox5a(display_short)|uniprotkb:Cytochrome c oxidase polypeptide Va(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Martins et al. (2018)	imex:IM-28469|pubmed:29476059	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26438079|imex:IM-28469-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSRNOG00000016271(gene)|ensembl:ENSRNOT00000023037(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001540"(amyloid-beta binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0010008"(endosome membrane)|go:"GO:0030660"(Golgi-associated vesicle membrane)|go:"GO:0031301"(integral component of organelle membrane)|go:"GO:0042985"(negative regulation of amyloid precursor protein biosynthetic process)|interpro:IPR007084(BRICHOS)|interpro:IPR040145|mint:Q5XIE8|refseq:NP_001006964.1|rgd:620727	ensembl:ENSRNOG00000018816(gene)|ensembl:ENSRNOT00000025525(transcript)|go:"GO:0004129"(cytochrome-c oxidase activity)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005751"(mitochondrial respiratory chain complex IV)|go:"GO:0006123"(mitochondrial electron transport, cytochrome c to oxygen)|go:"GO:0046872"(metal ion binding)|interpro:IPR003204(Cytochrome c oxidase, subunit Va)|interpro:IPR036545|mint:P11240|reactome:R-RNO-5628897|reactome:R-RNO-611105|reactome:R-RNO-9707564|rgd:620607|refseq:NP_665726.1	-	-	-	figure legend:ST1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10116(rat-brain-cerebellum)|taxid:10116(Rattus norvegicus)	-	2020/10/30	2020/10/30	rogid:DtE+ZXAZKdCMvUW5K+jXQ5bH07M10116	rogid:Q35b6ItDmdEEx57GuPXOA3rR8qM10116	rigid:OaXQ9NA25fwCWxejPU3Ao9q5j/E	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q5XIE8	uniprotkb:P97536	intact:EBI-15348306|ensembl:ENSRNOP00000023037	intact:EBI-918083|ensembl:ENSRNOP00000010720	psi-mi:itm2b_rat(display_long)|uniprotkb:Itm2b(gene name)|psi-mi:Itm2b(display_short)|uniprotkb:Immature BRI2(gene name synonym)|uniprotkb:Transmembrane protein BRI(gene name synonym)	psi-mi:cand1_rat(display_long)|uniprotkb:Cullin-associated and neddylation-dissociated protein 1(gene name synonym)|uniprotkb:p120 CAND1(gene name synonym)|uniprotkb:TBP-interacting protein of 120 kDa A(gene name synonym)|uniprotkb:Cand1(gene name)|psi-mi:Cand1(display_short)|uniprotkb:Tip120(gene name synonym)|uniprotkb:Tip120a(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Martins et al. (2018)	imex:IM-28469|pubmed:29476059	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26438079|imex:IM-28469-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSRNOG00000016271(gene)|ensembl:ENSRNOT00000023037(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001540"(amyloid-beta binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0010008"(endosome membrane)|go:"GO:0030660"(Golgi-associated vesicle membrane)|go:"GO:0031301"(integral component of organelle membrane)|go:"GO:0042985"(negative regulation of amyloid precursor protein biosynthetic process)|interpro:IPR007084(BRICHOS)|interpro:IPR040145|mint:Q5XIE8|refseq:NP_001006964.1|rgd:620727	rgd:620479|refseq:NP_446456.1|ensembl:ENSRNOG00000007834(gene)|ensembl:ENSRNOT00000010720(transcript)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0010265"(SCF complex assembly)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0017025"(TBP-class protein binding)|go:"GO:0030154"(cell differentiation)|go:"GO:0031461"(cullin-RING ubiquitin ligase complex)|go:"GO:0043086"(negative regulation of catalytic activity)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045899"(positive regulation of RNA polymerase II transcription preinitiation complex assembly)|interpro:IPR013932("TATA-binding protein interacting (TIP20)")|interpro:IPR016024(Armadillo-type fold)|interpro:IPR039852|mint:P97536|reactome:R-RNO-6798695|reactome:R-RNO-8951664|reactome:R-RNO-917937	-	-	-	figure legend:ST1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10116(rat-brain-cerebellum)|taxid:10116(Rattus norvegicus)	-	2020/10/30	2020/10/30	rogid:DtE+ZXAZKdCMvUW5K+jXQ5bH07M10116	rogid:AYiE0tEiNw1ias86oxC6CxJm5uo10116	rigid:OaXQ9NA25fwCWxejPU3Ao9q5j/E	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q5XIE8	uniprotkb:P00564	intact:EBI-15348306|ensembl:ENSRNOP00000023037	intact:EBI-26436829|uniprotkb:Q6P6R9	psi-mi:itm2b_rat(display_long)|uniprotkb:Itm2b(gene name)|psi-mi:Itm2b(display_short)|uniprotkb:Immature BRI2(gene name synonym)|uniprotkb:Transmembrane protein BRI(gene name synonym)	psi-mi:kcrm_rat(display_long)|uniprotkb:Ckm(gene name)|psi-mi:Ckm(display_short)|uniprotkb:Ckmm(gene name synonym)|uniprotkb:Creatine kinase M chain(gene name synonym)|uniprotkb:Creatine phosphokinase M-type(gene name synonym)|uniprotkb:M-CK(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Martins et al. (2018)	imex:IM-28469|pubmed:29476059	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26438079|imex:IM-28469-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSRNOG00000016271(gene)|ensembl:ENSRNOT00000023037(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001540"(amyloid-beta binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0010008"(endosome membrane)|go:"GO:0030660"(Golgi-associated vesicle membrane)|go:"GO:0031301"(integral component of organelle membrane)|go:"GO:0042985"(negative regulation of amyloid precursor protein biosynthetic process)|interpro:IPR007084(BRICHOS)|interpro:IPR040145|mint:Q5XIE8|refseq:NP_001006964.1|rgd:620727	go:"GO:0004111"(creatine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005737"(cytoplasm)|go:"GO:0009408"(response to heat)|go:"GO:0016301"(kinase activity)|go:"GO:0046314"(phosphocreatine biosynthetic process)|reactome:R-RNO-71288|mint:P00564|refseq:NP_036662.1|interpro:IPR000749("ATP:guanido phosphotransferase")|interpro:IPR022415|interpro:IPR022414|interpro:IPR022413|interpro:IPR036802|interpro:IPR014746(Glutamine synthetase/guanido kinase, catalytic region)|rgd:2358	-	-	-	figure legend:ST1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10116(rat-brain-cerebellum)|taxid:10116(Rattus norvegicus)	-	2020/10/30	2020/10/30	rogid:DtE+ZXAZKdCMvUW5K+jXQ5bH07M10116	rogid:HUwtOLpKEeqrxa326Rz+yjZ6/Mo10116	rigid:OaXQ9NA25fwCWxejPU3Ao9q5j/E	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q5XIE8	uniprotkb:P48199	intact:EBI-15348306|ensembl:ENSRNOP00000023037	intact:EBI-26436778|ensembl:ENSRNOP00000000058|uniprotkb:Q5BK94	psi-mi:itm2b_rat(display_long)|uniprotkb:Itm2b(gene name)|psi-mi:Itm2b(display_short)|uniprotkb:Immature BRI2(gene name synonym)|uniprotkb:Transmembrane protein BRI(gene name synonym)	psi-mi:crp_rat(display_long)|uniprotkb:Crp(gene name)|psi-mi:Crp(display_short)|uniprotkb:Ptx1(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Martins et al. (2018)	imex:IM-28469|pubmed:29476059	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26438079|imex:IM-28469-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSRNOG00000016271(gene)|ensembl:ENSRNOT00000023037(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001540"(amyloid-beta binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0010008"(endosome membrane)|go:"GO:0030660"(Golgi-associated vesicle membrane)|go:"GO:0031301"(integral component of organelle membrane)|go:"GO:0042985"(negative regulation of amyloid precursor protein biosynthetic process)|interpro:IPR007084(BRICHOS)|interpro:IPR040145|mint:Q5XIE8|refseq:NP_001006964.1|rgd:620727	go:"GO:0071354"(cellular response to interleukin-6)|go:"GO:0071732"(cellular response to nitric oxide)|go:"GO:1900006"(positive regulation of dendrite development)|interpro:IPR001759(Pentaxin)|interpro:IPR013320(Concanavalin A-like lectin/glucanase, subgroup)|interpro:IPR030476|mint:P48199|reactome:R-RNO-173623|go:"GO:0071277"(cellular response to calcium ion)|ensembl:ENSRNOG00000000053(gene)|ensembl:ENSRNOT00000000058(transcript)|go:"GO:0001666"(response to hypoxia)|go:"GO:0007568"(aging)|go:"GO:0009314"(response to radiation)|go:"GO:0010288"(response to lead ion)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010745"(negative regulation of macrophage derived foam cell differentiation)|go:"GO:0010888"(negative regulation of lipid storage)|go:"GO:0010988"(regulation of low-density lipoprotein particle clearance)|go:"GO:0015485"(cholesterol binding)|go:"GO:0030169"(low-density lipoprotein particle binding)|go:"GO:0030175"(filopodium)|go:"GO:0030426"(growth cone)|go:"GO:0031667"(response to nutrient levels)|go:"GO:0001849"(complement component C1q complex binding)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005615"(extracellular space)|go:"GO:0006953"(acute-phase response)|go:"GO:0006958"(complement activation, classical pathway)|go:"GO:0032355"(response to estradiol)|go:"GO:0032677"(regulation of interleukin-8 production)|go:"GO:0032929"(negative regulation of superoxide anion generation)|go:"GO:0032930"(positive regulation of superoxide anion generation)|go:"GO:0032945"(negative regulation of mononuclear cell proliferation)|go:"GO:0033574"(response to testosterone)|go:"GO:0042060"(wound healing)|go:"GO:0042310"(vasoconstriction)|go:"GO:0042802"(identical protein binding)|go:"GO:0044793"(negative regulation by host of viral process)|go:"GO:0045087"(innate immune response)|go:"GO:0045429"(positive regulation of nitric oxide biosynthetic process)|go:"GO:0045471"(response to ethanol)|go:"GO:0050750"(low-density lipoprotein particle receptor binding)|go:"GO:0051258"(protein polymerization)|refseq:NP_058792.1|rgd:2411	-	-	-	figure legend:ST1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10116(rat-brain-cerebellum)|taxid:10116(Rattus norvegicus)	-	2020/10/30	2020/10/30	rogid:DtE+ZXAZKdCMvUW5K+jXQ5bH07M10116	rogid:Ozl0mdX5dYR0k5iGFvBOoCZpFYI10116	rigid:OaXQ9NA25fwCWxejPU3Ao9q5j/E	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q5XIE8	uniprotkb:Q02874	intact:EBI-15348306|ensembl:ENSRNOP00000023037	intact:EBI-26436710|ensembl:ENSRNOP00000049143|uniprotkb:O09140|uniprotkb:Q63325	psi-mi:itm2b_rat(display_long)|uniprotkb:Itm2b(gene name)|psi-mi:Itm2b(display_short)|uniprotkb:Immature BRI2(gene name synonym)|uniprotkb:Transmembrane protein BRI(gene name synonym)	psi-mi:h2ay_rat(display_long)|uniprotkb:Macroh2a1(gene name)|psi-mi:Macroh2a1(display_short)|uniprotkb:H2afy(gene name synonym)|uniprotkb:H2A.y(gene name synonym)|uniprotkb:H2A/y(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Martins et al. (2018)	imex:IM-28469|pubmed:29476059	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26438079|imex:IM-28469-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSRNOG00000016271(gene)|ensembl:ENSRNOT00000023037(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001540"(amyloid-beta binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0010008"(endosome membrane)|go:"GO:0030660"(Golgi-associated vesicle membrane)|go:"GO:0031301"(integral component of organelle membrane)|go:"GO:0042985"(negative regulation of amyloid precursor protein biosynthetic process)|interpro:IPR007084(BRICHOS)|interpro:IPR040145|mint:Q5XIE8|refseq:NP_001006964.1|rgd:620727	ensembl:ENSRNOG00000011523(gene)|ensembl:ENSRNOT00000051702(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000182"(rDNA binding)|go:"GO:0000793"(condensed chromosome)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000979"(RNA polymerase II core promoter sequence-specific DNA binding)|go:"GO:0001740"(Barr body)|go:"GO:0000228"(nuclear chromosome)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005721"(pericentric heterochromatin)|go:"GO:0000785"(chromatin)|go:"GO:0005730"(nucleolus)|go:"GO:0006334"(nucleosome assembly)|go:"GO:0006342"|go:"GO:0007549"(dosage compensation)|go:"GO:0010385"(double-stranded methylated DNA binding)|go:"GO:0019216"(regulation of lipid metabolic process)|go:"GO:0019899"(enzyme binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030291"(protein serine/threonine kinase inhibitor activity)|go:"GO:0031490"(chromatin DNA binding)|go:"GO:0031492"(nucleosomal DNA binding)|go:"GO:0033128"(negative regulation of histone phosphorylation)|go:"GO:0034184"(positive regulation of maintenance of mitotic sister chromatid cohesion)|go:"GO:0040029"(regulation of gene expression, epigenetic)|go:"GO:0045618"(positive regulation of keratinocyte differentiation)|go:"GO:0045814"(negative regulation of gene expression, epigenetic)|go:"GO:0045815"(epigenetic maintenance of chromatin in transcription-competent conformation)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0051572"(negative regulation of histone H3-K4 methylation)|go:"GO:0061086"(negative regulation of histone H3-K27 methylation)|go:"GO:0071169"(establishment of protein localization to chromatin)|go:"GO:0000786"(nucleosome)|go:"GO:0071901"(negative regulation of protein serine/threonine kinase activity)|go:"GO:1901837"(negative regulation of transcription of nucleolar large rRNA by RNA polymerase I)|go:"GO:1902750"(negative regulation of cell cycle G2/M phase transition)|go:"GO:1902882"(regulation of response to oxidative stress)|go:"GO:1902884"(positive regulation of response to oxidative stress)|go:"GO:1902883"(negative regulation of response to oxidative stress)|go:"GO:1903226"(positive regulation of endodermal cell differentiation)|go:"GO:1904815"(negative regulation of protein localization to chromosome, telomeric region)|go:"GO:1990841"(promoter-specific chromatin binding)|interpro:IPR002119(Histone H2A)|interpro:IPR002589(Appr-1-p processing)|interpro:IPR007125(Histone core)|interpro:IPR009072(Histone-fold)|interpro:IPR021171|interpro:IPR032454|interpro:IPR035796|interpro:IPR043472|mint:Q02874|rcsb pdb:1YD9|refseq:NP_058878.1|refseq:XP_006253638.1|rgd:621462	-	-	-	figure legend:ST1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10116(rat-brain-cerebellum)|taxid:10116(Rattus norvegicus)	-	2020/10/30	2020/10/30	rogid:DtE+ZXAZKdCMvUW5K+jXQ5bH07M10116	rogid:Sm9jd2ZEiFHf8hPVDkxvoX0FDl810116	rigid:OaXQ9NA25fwCWxejPU3Ao9q5j/E	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q5XIE8	uniprotkb:O35796	intact:EBI-15348306|ensembl:ENSRNOP00000023037	intact:EBI-915544|uniprotkb:Q6IRS5|ensembl:ENSRNOP00000031020	psi-mi:itm2b_rat(display_long)|uniprotkb:Itm2b(gene name)|psi-mi:Itm2b(display_short)|uniprotkb:Immature BRI2(gene name synonym)|uniprotkb:Transmembrane protein BRI(gene name synonym)	psi-mi:c1qbp_rat(display_long)|uniprotkb:Glycoprotein gC1qBP(gene name synonym)|uniprotkb:GC1q-R protein(gene name synonym)|uniprotkb:C1qbp(gene name)|psi-mi:C1qbp(display_short)|uniprotkb:Gc1qbp(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Martins et al. (2018)	imex:IM-28469|pubmed:29476059	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26438079|imex:IM-28469-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSRNOG00000016271(gene)|ensembl:ENSRNOT00000023037(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001540"(amyloid-beta binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0010008"(endosome membrane)|go:"GO:0030660"(Golgi-associated vesicle membrane)|go:"GO:0031301"(integral component of organelle membrane)|go:"GO:0042985"(negative regulation of amyloid precursor protein biosynthetic process)|interpro:IPR007084(BRICHOS)|interpro:IPR040145|mint:Q5XIE8|refseq:NP_001006964.1|rgd:620727	rgd:2230|refseq:NP_062132.2|ensembl:ENSRNOG00000006949(gene)|ensembl:ENSRNOT00000037517(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0001849"(complement component C1q complex binding)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0003729"(mRNA binding)|go:"GO:0005080"(protein kinase C binding)|go:"GO:0005540"(hyaluronic acid binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005634"(nucleus)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006397"(mRNA processing)|go:"GO:0006915"(apoptotic process)|go:"GO:0006955"(immune response)|go:"GO:0006958"(complement activation, classical pathway)|go:"GO:0008380"(RNA splicing)|go:"GO:0008494"(translation activator activity)|go:"GO:0009986"(cell surface)|go:"GO:0014065"(phosphatidylinositol 3-kinase signaling)|go:"GO:0016020"(membrane)|go:"GO:0030449"(regulation of complement activation)|go:"GO:0030984"(kininogen binding)|go:"GO:0031690"(adrenergic receptor binding)|go:"GO:0032689"(negative regulation of interferon-gamma production)|go:"GO:0032695"(negative regulation of interleukin-12 production)|go:"GO:0039534"(negative regulation of MDA-5 signaling pathway)|go:"GO:0039536"(negative regulation of RIG-I signaling pathway)|go:"GO:0042256"(mature ribosome assembly)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0045087"(innate immune response)|go:"GO:0045785"(positive regulation of cell adhesion)|go:"GO:0048025"(negative regulation of mRNA splicing, via spliceosome)|go:"GO:0048786"(presynaptic active zone)|go:"GO:0050687"(negative regulation of defense response to virus)|go:"GO:0051897"(positive regulation of protein kinase B signaling)|go:"GO:0070131"(positive regulation of mitochondrial translation)|go:"GO:0090023"(positive regulation of neutrophil chemotaxis)|go:"GO:0097177"(mitochondrial ribosome binding)|go:"GO:0098793"(presynapse)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0098982"(GABA-ergic synapse)|go:"GO:1900026"(positive regulation of substrate adhesion-dependent cell spreading)|go:"GO:1901165"(positive regulation of trophoblast cell migration)|go:"GO:2000510"(positive regulation of dendritic cell chemotaxis)|interpro:IPR003428(Mitochondrial glycoprotein)|interpro:IPR036561|mint:O35796|reactome:R-RNO-140837|reactome:R-RNO-8980692|reactome:R-RNO-9013106	-	-	-	figure legend:ST1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10116(rat-brain-cerebellum)|taxid:10116(Rattus norvegicus)	-	2020/10/30	2020/10/30	rogid:DtE+ZXAZKdCMvUW5K+jXQ5bH07M10116	rogid:t5x39iyP/nNXaEYhXq6vWYG7jP810116	rigid:OaXQ9NA25fwCWxejPU3Ao9q5j/E	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q5XIE8	uniprotkb:P13941	intact:EBI-15348306|ensembl:ENSRNOP00000023037	intact:EBI-1374361|uniprotkb:O70604|uniprotkb:Q5PQT6|ensembl:ENSRNOP00000004956	psi-mi:itm2b_rat(display_long)|uniprotkb:Itm2b(gene name)|psi-mi:Itm2b(display_short)|uniprotkb:Immature BRI2(gene name synonym)|uniprotkb:Transmembrane protein BRI(gene name synonym)	psi-mi:co3a1_rat(display_long)|uniprotkb:Col3a1(gene name)|psi-mi:Col3a1(display_short)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Martins et al. (2018)	imex:IM-28469|pubmed:29476059	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26438079|imex:IM-28469-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSRNOG00000016271(gene)|ensembl:ENSRNOT00000023037(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001540"(amyloid-beta binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0010008"(endosome membrane)|go:"GO:0030660"(Golgi-associated vesicle membrane)|go:"GO:0031301"(integral component of organelle membrane)|go:"GO:0042985"(negative regulation of amyloid precursor protein biosynthetic process)|interpro:IPR007084(BRICHOS)|interpro:IPR040145|mint:Q5XIE8|refseq:NP_001006964.1|rgd:620727	rgd:71029|refseq:NP_114474.1|ensembl:ENSRNOG00000003357(gene)|ensembl:ENSRNOT00000004956(transcript)|go:"GO:0001501"(skeletal system development)|go:"GO:0001568"(blood vessel development)|go:"GO:0002020"(protease binding)|go:"GO:0005178"(integrin binding)|go:"GO:0005201"(extracellular matrix structural constituent)|go:"GO:0005581"(collagen trimer)|go:"GO:0005586"(collagen type III trimer)|go:"GO:0005615"(extracellular space)|go:"GO:0007160"(cell-matrix adhesion)|go:"GO:0007179"(transforming growth factor beta receptor signaling pathway)|go:"GO:0007229"(integrin-mediated signaling pathway)|go:"GO:0007507"(heart development)|go:"GO:0009314"(response to radiation)|go:"GO:0009612"(response to mechanical stimulus)|go:"GO:0018149"(peptide cross-linking)|go:"GO:0021987"(cerebral cortex development)|go:"GO:0030198"(extracellular matrix organization)|go:"GO:0030199"(collagen fibril organization)|go:"GO:0031012"(extracellular matrix)|go:"GO:0034097"(response to cytokine)|go:"GO:0035025"(positive regulation of Rho protein signal transduction)|go:"GO:0042060"(wound healing)|go:"GO:0043588"(skin development)|go:"GO:0046332"(SMAD binding)|go:"GO:0046872"(metal ion binding)|go:"GO:0048407"(platelet-derived growth factor binding)|go:"GO:0048565"(digestive tract development)|go:"GO:0050777"(negative regulation of immune response)|go:"GO:0060414"(aorta smooth muscle tissue morphogenesis)|go:"GO:0062023"(collagen-containing extracellular matrix)|go:"GO:0071230"(cellular response to amino acid stimulus)|go:"GO:0097435"(supramolecular fiber organization)|go:"GO:2001223"(negative regulation of neuron migration)|interpro:IPR000885(Fibrillar collagen, C-terminal)|interpro:IPR001007(von Willebrand factor, type C)|interpro:IPR008160(Collagen triple helix repeat)|mint:P13941|reactome:R-RNO-1442490|reactome:R-RNO-1474244|reactome:R-RNO-1650814|reactome:R-RNO-186797|reactome:R-RNO-198933|reactome:R-RNO-2022090|reactome:R-RNO-216083|reactome:R-RNO-3000171|reactome:R-RNO-3000178|reactome:R-RNO-419037|reactome:R-RNO-8874081|reactome:R-RNO-8948216	-	-	-	figure legend:ST1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10116(rat-brain-cerebellum)|taxid:10116(Rattus norvegicus)	-	2020/10/30	2020/10/30	rogid:DtE+ZXAZKdCMvUW5K+jXQ5bH07M10116	rogid:oVdVAcqVlcJuQJYPRDa+nzAVjyI10116	rigid:OaXQ9NA25fwCWxejPU3Ao9q5j/E	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q5XIE8	uniprotkb:Q99JD4	intact:EBI-15348306|ensembl:ENSRNOP00000023037	intact:EBI-26373639|ensembl:ENSRNOP00000012545	psi-mi:itm2b_rat(display_long)|uniprotkb:Itm2b(gene name)|psi-mi:Itm2b(display_short)|uniprotkb:Immature BRI2(gene name synonym)|uniprotkb:Transmembrane protein BRI(gene name synonym)	psi-mi:clap2_rat(display_long)|uniprotkb:Cytoplasmic linker-associated protein 2(gene name synonym)|uniprotkb:Clasp2(gene name)|psi-mi:Clasp2(display_short)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Martins et al. (2018)	imex:IM-28469|pubmed:29476059	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26438079|imex:IM-28469-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSRNOG00000016271(gene)|ensembl:ENSRNOT00000023037(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001540"(amyloid-beta binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0010008"(endosome membrane)|go:"GO:0030660"(Golgi-associated vesicle membrane)|go:"GO:0031301"(integral component of organelle membrane)|go:"GO:0042985"(negative regulation of amyloid precursor protein biosynthetic process)|interpro:IPR007084(BRICHOS)|interpro:IPR040145|mint:Q5XIE8|refseq:NP_001006964.1|rgd:620727	ensembl:ENSRNOG00000009161(gene)|ensembl:ENSRNOT00000012545(transcript)|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0000776"(kinetochore)|go:"GO:0002162"(dystroglycan binding)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0005815"(microtubule organizing center)|go:"GO:0005874"(microtubule)|go:"GO:0005876"(spindle microtubule)|go:"GO:0005881"(cytoplasmic microtubule)|go:"GO:0005886"(plasma membrane)|go:"GO:0005938"(cell cortex)|go:"GO:0006903"(vesicle targeting)|go:"GO:0007020"(microtubule nucleation)|go:"GO:0007026"(negative regulation of microtubule depolymerization)|go:"GO:0007030"(Golgi organization)|go:"GO:0007052"(mitotic spindle organization)|go:"GO:0007163"(establishment or maintenance of cell polarity)|go:"GO:0031252"(cell leading edge)|go:"GO:0032587"(ruffle membrane)|go:"GO:0032869"(cellular response to insulin stimulus)|go:"GO:0032886"(regulation of microtubule-based process)|go:"GO:0034453"(microtubule anchoring)|go:"GO:0040001"(establishment of mitotic spindle localization)|go:"GO:0008017"(microtubule binding)|go:"GO:0010458"(exit from mitosis)|go:"GO:0010470"(regulation of gastrulation)|go:"GO:0010634"(positive regulation of epithelial cell migration)|go:"GO:0010717"(regulation of epithelial to mesenchymal transition)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0016477"(cell migration)|go:"GO:0031023"(microtubule organizing center organization)|go:"GO:0031110"(regulation of microtubule polymerization or depolymerization)|go:"GO:0045180"(basal cortex)|go:"GO:0045921"(positive regulation of exocytosis)|go:"GO:0051010"(microtubule plus-end binding)|go:"GO:0051301"(cell division)|go:"GO:0051497"(negative regulation of stress fiber assembly)|go:"GO:0051895"(negative regulation of focal adhesion assembly)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0072686"(mitotic spindle)|go:"GO:0090091"(positive regulation of extracellular matrix disassembly)|go:"GO:0090307"(mitotic spindle assembly)|go:"GO:1903690"(negative regulation of wound healing, spreading of epidermal cells)|go:"GO:1904261"(positive regulation of basement membrane assembly involved in embryonic body morphogenesis)|go:"GO:1905477"(positive regulation of protein localization to membrane)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR024395|interpro:IPR034085|mint:Q99JD4|reactome:R-RNO-141444|reactome:R-RNO-2467813|reactome:R-RNO-2500257|reactome:R-RNO-5663220|reactome:R-RNO-68877|reactome:R-RNO-9648025|rgd:619789|refseq:NP_446174.1	-	-	-	figure legend:ST1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10116(rat-brain-cerebellum)|taxid:10116(Rattus norvegicus)	-	2020/10/30	2020/10/30	rogid:DtE+ZXAZKdCMvUW5K+jXQ5bH07M10116	rogid:JzNzJ7ff+QDPkDAI8ES1+TpZshU10116	rigid:OaXQ9NA25fwCWxejPU3Ao9q5j/E	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q5XIE8	uniprotkb:Q1WIM1	intact:EBI-15348306|ensembl:ENSRNOP00000023037	intact:EBI-26436676	psi-mi:itm2b_rat(display_long)|uniprotkb:Itm2b(gene name)|psi-mi:Itm2b(display_short)|uniprotkb:Immature BRI2(gene name synonym)|uniprotkb:Transmembrane protein BRI(gene name synonym)	psi-mi:cadm4_rat(display_long)|uniprotkb:Immunoglobulin superfamily member 4C(gene name synonym)|uniprotkb:Nectin-like protein 4(gene name synonym)|uniprotkb:Cadm4(gene name)|psi-mi:Cadm4(display_short)|uniprotkb:Igsf4c(gene name synonym)|uniprotkb:Necl4(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Martins et al. (2018)	imex:IM-28469|pubmed:29476059	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26438079|imex:IM-28469-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSRNOG00000016271(gene)|ensembl:ENSRNOT00000023037(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001540"(amyloid-beta binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0010008"(endosome membrane)|go:"GO:0030660"(Golgi-associated vesicle membrane)|go:"GO:0031301"(integral component of organelle membrane)|go:"GO:0042985"(negative regulation of amyloid precursor protein biosynthetic process)|interpro:IPR007084(BRICHOS)|interpro:IPR040145|mint:Q5XIE8|refseq:NP_001006964.1|rgd:620727	go:"GO:0035020"(regulation of Rac protein signal transduction)|go:"GO:0042127"(regulation of cell population proliferation)|go:"GO:0043183"(vascular endothelial growth factor receptor 1 binding)|go:"GO:0043184"(vascular endothelial growth factor receptor 2 binding)|go:"GO:0044291"(cell-cell contact zone)|go:"GO:0050732"(negative regulation of peptidyl-tyrosine phosphorylation)|go:"GO:0061041"(regulation of wound healing)|go:"GO:1900747"(negative regulation of vascular endothelial growth factor signaling pathway)|go:"GO:2000145"(regulation of cell motility)|go:"GO:0001932"(regulation of protein phosphorylation)|go:"GO:0001933"(negative regulation of protein phosphorylation)|go:"GO:0007155"(cell adhesion)|go:"GO:0010801"(negative regulation of peptidyl-threonine phosphorylation)|go:"GO:0016021"(integral component of membrane)|go:"GO:0019903"(protein phosphatase binding)|go:"GO:0030948"(negative regulation of vascular endothelial growth factor receptor signaling pathway)|go:"GO:0030971"(receptor tyrosine kinase binding)|go:"GO:0031252"(cell leading edge)|mint:Q1WIM1|refseq:NP_001040572.1|interpro:IPR028807|interpro:IPR013162(CD80-like, immunoglobulin C2-set)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR036179|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR003599(Immunoglobulin subtype)|interpro:IPR003598(Immunoglobulin subtype 2)|interpro:IPR013106(Immunoglobulin V-set)|interpro:IPR003585(Neurexin/syndecan/glycophorin C)|rgd:1304722	-	-	-	figure legend:ST1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10116(rat-brain-cerebellum)|taxid:10116(Rattus norvegicus)	-	2020/10/30	2020/10/30	rogid:DtE+ZXAZKdCMvUW5K+jXQ5bH07M10116	rogid:3V7nCH4ibfb52GJpOonnfzbZN4M10116	rigid:OaXQ9NA25fwCWxejPU3Ao9q5j/E	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q5XIE8	uniprotkb:Q5M7A7	intact:EBI-15348306|ensembl:ENSRNOP00000023037	intact:EBI-26436660|ensembl:ENSRNOP00000007104|uniprotkb:A2RQR5	psi-mi:itm2b_rat(display_long)|uniprotkb:Itm2b(gene name)|psi-mi:Itm2b(display_short)|uniprotkb:Immature BRI2(gene name synonym)|uniprotkb:Transmembrane protein BRI(gene name synonym)	psi-mi:cnrp1_rat(display_long)|uniprotkb:Cnrip1(gene name)|psi-mi:Cnrip1(display_short)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Martins et al. (2018)	imex:IM-28469|pubmed:29476059	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26438079|imex:IM-28469-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSRNOG00000016271(gene)|ensembl:ENSRNOT00000023037(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001540"(amyloid-beta binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0010008"(endosome membrane)|go:"GO:0030660"(Golgi-associated vesicle membrane)|go:"GO:0031301"(integral component of organelle membrane)|go:"GO:0042985"(negative regulation of amyloid precursor protein biosynthetic process)|interpro:IPR007084(BRICHOS)|interpro:IPR040145|mint:Q5XIE8|refseq:NP_001006964.1|rgd:620727	ensembl:ENSRNOG00000005326(gene)|ensembl:ENSRNOT00000007104(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0031718"(type 1 cannabinoid receptor binding)|go:"GO:2000272"(negative regulation of signaling receptor activity)|interpro:IPR029204|mint:Q5M7A7|refseq:NP_001014254.1|rgd:1308373	-	-	-	figure legend:ST1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10116(rat-brain-cerebellum)|taxid:10116(Rattus norvegicus)	-	2020/10/30	2020/10/30	rogid:DtE+ZXAZKdCMvUW5K+jXQ5bH07M10116	rogid:0sIrvk+HMxIQ6GshuxoME8uWdVY10116	rigid:OaXQ9NA25fwCWxejPU3Ao9q5j/E	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q5XIE8	uniprotkb:P48284	intact:EBI-15348306|ensembl:ENSRNOP00000023037	intact:EBI-26436620|uniprotkb:Q4QR97	psi-mi:itm2b_rat(display_long)|uniprotkb:Itm2b(gene name)|psi-mi:Itm2b(display_short)|uniprotkb:Immature BRI2(gene name synonym)|uniprotkb:Transmembrane protein BRI(gene name synonym)	psi-mi:cah4_rat(display_long)|uniprotkb:Carbonate dehydratase IV(gene name synonym)|uniprotkb:Carbonic anhydrase IV(gene name synonym)|uniprotkb:Ca4(gene name)|psi-mi:Ca4(display_short)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Martins et al. (2018)	imex:IM-28469|pubmed:29476059	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26438079|imex:IM-28469-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSRNOG00000016271(gene)|ensembl:ENSRNOT00000023037(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001540"(amyloid-beta binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0010008"(endosome membrane)|go:"GO:0030660"(Golgi-associated vesicle membrane)|go:"GO:0031301"(integral component of organelle membrane)|go:"GO:0042985"(negative regulation of amyloid precursor protein biosynthetic process)|interpro:IPR007084(BRICHOS)|interpro:IPR040145|mint:Q5XIE8|refseq:NP_001006964.1|rgd:620727	go:"GO:0004089"(carbonate dehydratase activity)|go:"GO:0005793"(endoplasmic reticulum-Golgi intermediate compartment)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0005886"(plasma membrane)|go:"GO:0006730"(one-carbon metabolic process)|go:"GO:0008270"(zinc ion binding)|go:"GO:0009986"(cell surface)|go:"GO:0015701"(bicarbonate transport)|go:"GO:0016020"(membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0016529"(sarcoplasmic reticulum)|go:"GO:0016836"(hydro-lyase activity)|go:"GO:0030658"(transport vesicle membrane)|go:"GO:0030667"(secretory granule membrane)|go:"GO:0031362"(anchored component of external side of plasma membrane)|go:"GO:0031526"(brush border membrane)|go:"GO:0005791"(rough endoplasmic reticulum)|go:"GO:0042493"|go:"GO:0046658"(anchored component of plasma membrane)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0048513"(animal organ development)|go:"GO:0048545"(response to steroid hormone)|go:"GO:0070062"(extracellular exosome)|reactome:R-RNO-1237044|reactome:R-RNO-1247673|reactome:R-RNO-1475029|go:"GO:0042383"(sarcolemma)|mint:P48284|refseq:NP_062047.1|interpro:IPR041874|interpro:IPR001148(Carbonic anhydrase, eukaryotic)|interpro:IPR036398|interpro:IPR023561|interpro:IPR018338|interpro:IPR018343|rgd:2242	-	-	-	figure legend:ST1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10116(rat-brain-cerebellum)|taxid:10116(Rattus norvegicus)	-	2020/10/30	2020/10/30	rogid:DtE+ZXAZKdCMvUW5K+jXQ5bH07M10116	rogid:Ki2CiA1ePnMvJY2IBeDiq9wTbFM10116	rigid:OaXQ9NA25fwCWxejPU3Ao9q5j/E	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q5XIE8	uniprotkb:Q07009	intact:EBI-15348306|ensembl:ENSRNOP00000023037	intact:EBI-1040438|ensembl:ENSRNOP00000046509	psi-mi:itm2b_rat(display_long)|uniprotkb:Itm2b(gene name)|psi-mi:Itm2b(display_short)|uniprotkb:Immature BRI2(gene name synonym)|uniprotkb:Transmembrane protein BRI(gene name synonym)	psi-mi:can2_rat(display_long)|uniprotkb:Capn2(gene name)|psi-mi:Capn2(display_short)|uniprotkb:Calpain-2 large subunit(gene name synonym)|uniprotkb:Calcium-activated neutral proteinase 2(gene name synonym)|uniprotkb:Calpain M-type(gene name synonym)|uniprotkb:Millimolar-calpain(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Martins et al. (2018)	imex:IM-28469|pubmed:29476059	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26438079|imex:IM-28469-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSRNOG00000016271(gene)|ensembl:ENSRNOT00000023037(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001540"(amyloid-beta binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0010008"(endosome membrane)|go:"GO:0030660"(Golgi-associated vesicle membrane)|go:"GO:0031301"(integral component of organelle membrane)|go:"GO:0042985"(negative regulation of amyloid precursor protein biosynthetic process)|interpro:IPR007084(BRICHOS)|interpro:IPR040145|mint:Q5XIE8|refseq:NP_001006964.1|rgd:620727	rgd:2268|refseq:NP_058812.1|ensembl:ENSRNOG00000034015(gene)|ensembl:ENSRNOT00000045326(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0001666"(response to hypoxia)|go:"GO:0001824"(blastocyst development)|go:"GO:0004198"(calcium-dependent cysteine-type endopeptidase activity)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005764"(lysosome)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005925"(focal adhesion)|go:"GO:0006508"(proteolysis)|go:"GO:0007520"(myoblast fusion)|go:"GO:0007565"(female pregnancy)|go:"GO:0008092"(cytoskeletal protein binding)|go:"GO:0008233"(peptidase activity)|go:"GO:0009897"(external side of plasma membrane)|go:"GO:0010666"(positive regulation of cardiac muscle cell apoptotic process)|go:"GO:0016020"(membrane)|go:"GO:0016540"(protein autoprocessing)|go:"GO:0019899"(enzyme binding)|go:"GO:0030425"(dendrite)|go:"GO:0031143"(pseudopodium)|go:"GO:0032675"(regulation of interleukin-6 production)|go:"GO:0035458"(cellular response to interferon-beta)|go:"GO:0042542"(response to hydrogen peroxide)|go:"GO:0042995"(cell projection)|go:"GO:0043025"(neuronal cell body)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045121"(membrane raft)|go:"GO:0048266"(behavioral response to pain)|go:"GO:0051493"(regulation of cytoskeleton organization)|go:"GO:0051603"(proteolysis involved in cellular protein catabolic process)|go:"GO:0071222"(cellular response to lipopolysaccharide)|go:"GO:0071230"(cellular response to amino acid stimulus)|go:"GO:0097038"(perinuclear endoplasmic reticulum)|go:"GO:1901216"(positive regulation of neuron death)|go:"GO:1901741"(positive regulation of myoblast fusion)|go:"GO:2001247"(positive regulation of phosphatidylcholine biosynthetic process)|interpro:IPR000169(Peptidase, cysteine peptidase active site)|interpro:IPR001300(Peptidase C2, calpain)|interpro:IPR002048(Calcium-binding EF-hand)|interpro:IPR011992(EF-Hand type)|interpro:IPR018247|interpro:IPR022682|interpro:IPR022683|interpro:IPR022684|interpro:IPR029539|interpro:IPR033883|interpro:IPR036213|interpro:IPR038765|interpro:IPR042736|mint:Q07009|rcsb pdb:1DF0|rcsb pdb:1MDW|rcsb pdb:1QXP|rcsb pdb:1U5I|rcsb pdb:3BOW|rcsb pdb:3DF0|reactome:R-RNO-1474228|dip:DIP-6139N	-	-	-	figure legend:ST1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10116(rat-brain-cerebellum)|taxid:10116(Rattus norvegicus)	-	2020/10/30	2020/10/30	rogid:DtE+ZXAZKdCMvUW5K+jXQ5bH07M10116	rogid:IAwBkfhb1+PtAZz2QDXOgLsU76I10116	rigid:OaXQ9NA25fwCWxejPU3Ao9q5j/E	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q5XIE8	uniprotkb:O35567	intact:EBI-15348306|ensembl:ENSRNOP00000023037	intact:EBI-10768817|uniprotkb:Q6IN16|ensembl:ENSRNOP00000021105	psi-mi:itm2b_rat(display_long)|uniprotkb:Itm2b(gene name)|psi-mi:Itm2b(display_short)|uniprotkb:Immature BRI2(gene name synonym)|uniprotkb:Transmembrane protein BRI(gene name synonym)	psi-mi:pur9_rat(display_long)|uniprotkb:AICAR transformylase/inosine monophosphate cyclohydrolase(gene name synonym)|uniprotkb:Atic(gene name)|psi-mi:Atic(display_short)|uniprotkb:Purh(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Martins et al. (2018)	imex:IM-28469|pubmed:29476059	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26438079|imex:IM-28469-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSRNOG00000016271(gene)|ensembl:ENSRNOT00000023037(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001540"(amyloid-beta binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0010008"(endosome membrane)|go:"GO:0030660"(Golgi-associated vesicle membrane)|go:"GO:0031301"(integral component of organelle membrane)|go:"GO:0042985"(negative regulation of amyloid precursor protein biosynthetic process)|interpro:IPR007084(BRICHOS)|interpro:IPR040145|mint:Q5XIE8|refseq:NP_001006964.1|rgd:620727	rgd:70879|refseq:NP_112276.2|go:"GO:0003360"(brainstem development)|go:"GO:0003937"(IMP cyclohydrolase activity)|go:"GO:0004643"(phosphoribosylaminoimidazolecarboxamide formyltransferase activity)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006189"('de novo' IMP biosynthetic process)|go:"GO:0009116"(nucleoside metabolic process)|ensembl:ENSRNOG00000015511(gene)|go:"GO:0009235"(cobalamin metabolic process)|go:"GO:0009259"(ribonucleotide metabolic process)|go:"GO:0010035"(response to inorganic substance)|go:"GO:0021549"(cerebellum development)|go:"GO:0021987"(cerebral cortex development)|go:"GO:0031100"(animal organ regeneration)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0046452"(dihydrofolate metabolic process)|go:"GO:0046654"(tetrahydrofolate biosynthetic process)|go:"GO:0098761"(cellular response to interleukin-7)|interpro:IPR002695(AICARFT/IMPCHase bienzyme)|interpro:IPR011607(MGS-like)|interpro:IPR016193(Cytidine deaminase-like)|interpro:IPR024050|interpro:IPR024051|interpro:IPR036914|mint:O35567|reactome:R-RNO-73817|ensembl:ENSRNOT00000021105(transcript)	-	-	-	figure legend:ST1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10116(rat-brain-cerebellum)|taxid:10116(Rattus norvegicus)	-	2020/10/30	2020/10/30	rogid:DtE+ZXAZKdCMvUW5K+jXQ5bH07M10116	rogid:o6Ga1fsJNW74MxIF2YKv6IDc/GQ10116	rigid:OaXQ9NA25fwCWxejPU3Ao9q5j/E	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q5XIE8	uniprotkb:P15178	intact:EBI-15348306|ensembl:ENSRNOP00000023037	intact:EBI-916576|ensembl:ENSRNOP00000005127	psi-mi:itm2b_rat(display_long)|uniprotkb:Itm2b(gene name)|psi-mi:Itm2b(display_short)|uniprotkb:Immature BRI2(gene name synonym)|uniprotkb:Transmembrane protein BRI(gene name synonym)	psi-mi:sydc_rat(display_long)|uniprotkb:Dars1(gene name)|psi-mi:Dars1(display_short)|uniprotkb:Aspartyl-tRNA synthetase(gene name synonym)|uniprotkb:Dars(gene name synonym)|uniprotkb:Drs1(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Martins et al. (2018)	imex:IM-28469|pubmed:29476059	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26438079|imex:IM-28469-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSRNOG00000016271(gene)|ensembl:ENSRNOT00000023037(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001540"(amyloid-beta binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0010008"(endosome membrane)|go:"GO:0030660"(Golgi-associated vesicle membrane)|go:"GO:0031301"(integral component of organelle membrane)|go:"GO:0042985"(negative regulation of amyloid precursor protein biosynthetic process)|interpro:IPR007084(BRICHOS)|interpro:IPR040145|mint:Q5XIE8|refseq:NP_001006964.1|rgd:620727	mint:P15178|ensembl:ENSRNOG00000003743(gene)|ensembl:ENSRNOT00000005127(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0004815"(aspartate-tRNA ligase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006422"(aspartyl-tRNA aminoacylation)|go:"GO:0017101"(aminoacyl-tRNA synthetase multienzyme complex)|go:"GO:0045202"(synapse)|interpro:IPR002312(Aspartyl-tRNA synthetase, class IIb)|interpro:IPR004364("Aminoacyl-tRNA synthetase, class II (D, K and N)")|interpro:IPR004365(Nucleic acid binding, OB-fold, tRNA/helicase-type)|interpro:IPR004523(Aspartyl-tRNA synthetase, class IIb, archea/euk type)|interpro:IPR006195(Aminoacyl-tRNA synthetase, class II)|interpro:IPR012340(Nucleic acid-binding, OB-fold)|rgd:621167|refseq:NP_446251.1	-	-	-	figure legend:ST1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10116(rat-brain-cerebellum)|taxid:10116(Rattus norvegicus)	-	2020/10/30	2020/10/30	rogid:DtE+ZXAZKdCMvUW5K+jXQ5bH07M10116	rogid:NGlGimpuRwgUtRYpEf4re1yGHno10116	rigid:OaXQ9NA25fwCWxejPU3Ao9q5j/E	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q5XIE8	uniprotkb:P00507	intact:EBI-15348306|ensembl:ENSRNOP00000023037	intact:EBI-915723|uniprotkb:Q64551|uniprotkb:Q9QV50|ensembl:ENSRNOP00000015956	psi-mi:itm2b_rat(display_long)|uniprotkb:Itm2b(gene name)|psi-mi:Itm2b(display_short)|uniprotkb:Immature BRI2(gene name synonym)|uniprotkb:Transmembrane protein BRI(gene name synonym)	psi-mi:aatm_rat(display_long)|uniprotkb:Plasma membrane-associated fatty acid-binding protein(gene name synonym)|uniprotkb:Transaminase A(gene name synonym)|uniprotkb:Glutamate oxaloacetate transaminase 2(gene name synonym)|uniprotkb:Fatty acid-binding protein(gene name synonym)|uniprotkb:Got2(gene name)|psi-mi:Got2(display_short)|uniprotkb:Maat(gene name synonym)|uniprotkb:Kynurenine aminotransferase 4(gene name synonym)|uniprotkb:Kynurenine aminotransferase IV(gene name synonym)|uniprotkb:Kynurenine--oxoglutarate transaminase 4(gene name synonym)|uniprotkb:Kynurenine--oxoglutarate transaminase IV(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Martins et al. (2018)	imex:IM-28469|pubmed:29476059	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26438079|imex:IM-28469-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSRNOG00000016271(gene)|ensembl:ENSRNOT00000023037(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001540"(amyloid-beta binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0010008"(endosome membrane)|go:"GO:0030660"(Golgi-associated vesicle membrane)|go:"GO:0031301"(integral component of organelle membrane)|go:"GO:0042985"(negative regulation of amyloid precursor protein biosynthetic process)|interpro:IPR007084(BRICHOS)|interpro:IPR040145|mint:Q5XIE8|refseq:NP_001006964.1|rgd:620727	rgd:2722|refseq:NP_037309.1|reactome:R-RNO-70263|reactome:R-RNO-8963693|reactome:R-RNO-8964539|ensembl:ENSRNOG00000011782(gene)|ensembl:ENSRNOT00000015956(transcript)|go:"GO:0004069"("L-aspartate:2-oxoglutarate aminotransferase activity")|go:"GO:0005543"(phospholipid binding)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0005886"(plasma membrane)|go:"GO:0006103"(2-oxoglutarate metabolic process)|go:"GO:0006107"(oxaloacetate metabolic process)|go:"GO:0006520"(cellular amino acid metabolic process)|go:"GO:0006531"(aspartate metabolic process)|go:"GO:0006532"(aspartate biosynthetic process)|go:"GO:0006533"(aspartate catabolic process)|go:"GO:0006536"(glutamate metabolic process)|go:"GO:0007565"(female pregnancy)|go:"GO:0007595"(lactation)|go:"GO:0009986"(cell surface)|go:"GO:0014850"(response to muscle activity)|go:"GO:0015908"(fatty acid transport)|go:"GO:0016212"(kynurenine-oxoglutarate transaminase activity)|go:"GO:0016597"(amino acid binding)|go:"GO:0019550"(glutamate catabolic process to aspartate)|go:"GO:0019551"(glutamate catabolic process to 2-oxoglutarate)|go:"GO:0019899"(enzyme binding)|go:"GO:0030170"(pyridoxal phosphate binding)|go:"GO:0030315"(T-tubule)|go:"GO:0031406"(carboxylic acid binding)|go:"GO:0032868"(response to insulin)|go:"GO:0032991"(protein-containing complex)|go:"GO:0042383"(sarcolemma)|go:"GO:0042802"(identical protein binding)|go:"GO:0043204"(perikaryon)|go:"GO:0043278"(response to morphine)|go:"GO:0043648"(dicarboxylic acid metabolic process)|go:"GO:0045471"(response to ethanol)|interpro:IPR000796(Aspartate/other aminotransferase)|interpro:IPR004838(Aminotransferases, class-I, pyridoxal-phosphate-binding site)|interpro:IPR004839(Aminotransferase, class I and II)|interpro:IPR015421(Pyridoxal phosphate-dependent transferase, major region, subdomain 1)|interpro:IPR015422(Pyridoxal phosphate-dependent transferase, major region, subdomain 2)|interpro:IPR015424(Pyridoxal phosphate-dependent transferase, major region)|mint:P00507|reactome:R-RNO-389661	-	-	-	figure legend:ST1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10116(rat-brain-cerebellum)|taxid:10116(Rattus norvegicus)	-	2020/10/30	2020/10/30	rogid:DtE+ZXAZKdCMvUW5K+jXQ5bH07M10116	rogid:DmuLdUQ/Ak7zSKqE7Viztf5O1CM10116	rigid:OaXQ9NA25fwCWxejPU3Ao9q5j/E	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q5XIE8	uniprotkb:Q62848	intact:EBI-15348306|ensembl:ENSRNOP00000023037	intact:EBI-4398879|ensembl:ENSRNOP00000013900	psi-mi:itm2b_rat(display_long)|uniprotkb:Itm2b(gene name)|psi-mi:Itm2b(display_short)|uniprotkb:Immature BRI2(gene name synonym)|uniprotkb:Transmembrane protein BRI(gene name synonym)	psi-mi:arfg1_rat(display_long)|uniprotkb:Arfgap1(gene name)|psi-mi:Arfgap1(display_short)|uniprotkb:Arf1gap(gene name synonym)|uniprotkb:ADP-ribosylation factor 1 GTPase-activating protein(gene name synonym)|uniprotkb:ARF1-directed GTPase-activating protein(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Martins et al. (2018)	imex:IM-28469|pubmed:29476059	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26438079|imex:IM-28469-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSRNOG00000016271(gene)|ensembl:ENSRNOT00000023037(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001540"(amyloid-beta binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0010008"(endosome membrane)|go:"GO:0030660"(Golgi-associated vesicle membrane)|go:"GO:0031301"(integral component of organelle membrane)|go:"GO:0042985"(negative regulation of amyloid precursor protein biosynthetic process)|interpro:IPR007084(BRICHOS)|interpro:IPR040145|mint:Q5XIE8|refseq:NP_001006964.1|rgd:620727	refseq:NP_659558.1|rgd:708452|refseq:XP_017446953.1|ensembl:ENSRNOG00000043150(gene)|ensembl:ENSRNOT00000013900(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0014069"(postsynaptic density)|go:"GO:0015031"(protein transport)|go:"GO:0016192"(vesicle-mediated transport)|go:"GO:0030100"(regulation of endocytosis)|go:"GO:0032012"(regulation of ARF protein signal transduction)|go:"GO:0045202"(synapse)|go:"GO:0046872"(metal ion binding)|interpro:IPR001164(Arf GTPase activating protein)|interpro:IPR037278|interpro:IPR038508|mint:Q62848|reactome:R-RNO-6807878|reactome:R-RNO-6811434|reactome:R-RNO-8856828	-	-	-	figure legend:ST1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10116(rat-brain-cerebellum)|taxid:10116(Rattus norvegicus)	-	2020/10/30	2020/10/30	rogid:DtE+ZXAZKdCMvUW5K+jXQ5bH07M10116	rogid:zGVo6jKRj3KWSXtp93bNvxnWdgY10116	rigid:OaXQ9NA25fwCWxejPU3Ao9q5j/E	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q5XIE8	uniprotkb:B5DFN2	intact:EBI-15348306|ensembl:ENSRNOP00000023037	intact:EBI-21995800|uniprotkb:D4A5X8|ensembl:ENSRNOP00000072856	psi-mi:itm2b_rat(display_long)|uniprotkb:Itm2b(gene name)|psi-mi:Itm2b(display_short)|uniprotkb:Immature BRI2(gene name synonym)|uniprotkb:Transmembrane protein BRI(gene name synonym)	psi-mi:sahh2_rat(display_long)|uniprotkb:IP3R-binding protein released with inositol 1,4,5-trisphosphate(gene name synonym)|uniprotkb:Putative adenosylhomocysteinase 2(gene name synonym)|uniprotkb:S-adenosyl-L-homocysteine hydrolase 2(gene name synonym)|uniprotkb:Ahcyl1(gene name)|psi-mi:Ahcyl1(display_short)|uniprotkb:Irbit(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Martins et al. (2018)	imex:IM-28469|pubmed:29476059	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26438079|imex:IM-28469-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSRNOG00000016271(gene)|ensembl:ENSRNOT00000023037(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001540"(amyloid-beta binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0010008"(endosome membrane)|go:"GO:0030660"(Golgi-associated vesicle membrane)|go:"GO:0031301"(integral component of organelle membrane)|go:"GO:0042985"(negative regulation of amyloid precursor protein biosynthetic process)|interpro:IPR007084(BRICHOS)|interpro:IPR040145|mint:Q5XIE8|refseq:NP_001006964.1|rgd:620727	rgd:1309768|refseq:XP_006233227.1|refseq:XP_006233228.1|refseq:XP_008759627.1|refseq:NP_001102031.1|ensembl:ENSRNOG00000018569(gene)|ensembl:ENSRNOT00000079993(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005829"(cytosol)|go:"GO:0006378"(mRNA polyadenylation)|go:"GO:0006611"(protein export from nucleus)|go:"GO:0006730"(one-carbon metabolic process)|go:"GO:0006915"(apoptotic process)|go:"GO:0010765"(positive regulation of sodium ion transport)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0031440"(regulation of mRNA 3'-end processing)|go:"GO:0032412"(regulation of ion transmembrane transporter activity)|go:"GO:0033353"(S-adenosylmethionine cycle)|go:"GO:0038166"(angiotensin-activated signaling pathway)|go:"GO:0042045"(epithelial fluid transport)|go:"GO:0042802"(identical protein binding)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0044070"(regulation of anion transport)|go:"GO:0044233"(mitochondria-associated endoplasmic reticulum membrane)|go:"GO:0051592"(response to calcium ion)|go:"GO:1990456"(mitochondrion-endoplasmic reticulum membrane tethering)|interpro:IPR000043(S-adenosyl-L-homocysteine hydrolase)|interpro:IPR015878(S-adenosyl-L-homocysteine hydrolase, NAD binding)|interpro:IPR020082|interpro:IPR036291|interpro:IPR042172|mint:B5DFN2|reactome:R-RNO-5578775	-	-	-	figure legend:ST1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10116(rat-brain-cerebellum)|taxid:10116(Rattus norvegicus)	-	2020/10/30	2020/10/30	rogid:DtE+ZXAZKdCMvUW5K+jXQ5bH07M10116	rogid:2uK8snlKcnUqqrqHm6R/Tgz3q8410116	rigid:OaXQ9NA25fwCWxejPU3Ao9q5j/E	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q5XIE8	uniprotkb:P21533	intact:EBI-15348306|ensembl:ENSRNOP00000023037	intact:EBI-916839|uniprotkb:Q4QRA9|uniprotkb:Q64624|uniprotkb:Q68G26|ensembl:ENSRNOP00000038065	psi-mi:itm2b_rat(display_long)|uniprotkb:Itm2b(gene name)|psi-mi:Itm2b(display_short)|uniprotkb:Immature BRI2(gene name synonym)|uniprotkb:Transmembrane protein BRI(gene name synonym)	psi-mi:rl6_rat(display_long)|uniprotkb:Neoplasm-related protein C140(gene name synonym)|uniprotkb:Rpl6(gene name)|psi-mi:Rpl6(display_short)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Martins et al. (2018)	imex:IM-28469|pubmed:29476059	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26438079|imex:IM-28469-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSRNOG00000016271(gene)|ensembl:ENSRNOT00000023037(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001540"(amyloid-beta binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0010008"(endosome membrane)|go:"GO:0030660"(Golgi-associated vesicle membrane)|go:"GO:0031301"(integral component of organelle membrane)|go:"GO:0042985"(negative regulation of amyloid precursor protein biosynthetic process)|interpro:IPR007084(BRICHOS)|interpro:IPR040145|mint:Q5XIE8|refseq:NP_001006964.1|rgd:620727	rgd:619826|refseq:NP_446423.2|refseq:XP_006249440.1|ensembl:ENSRNOG00000025936(gene)|ensembl:ENSRNOT00000034951(transcript)|go:"GO:0000027"(ribosomal large subunit assembly)|go:"GO:0000049"(tRNA binding)|go:"GO:0002181"(cytoplasmic translation)|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005634"(nucleus)|go:"GO:0005791"(rough endoplasmic reticulum)|go:"GO:0014069"(postsynaptic density)|go:"GO:0022625"(cytosolic large ribosomal subunit)|go:"GO:0022626"(cytosolic ribosome)|go:"GO:0031672"(A band)|go:"GO:0036464"(cytoplasmic ribonucleoprotein granule)|go:"GO:0042788"(polysomal ribosome)|go:"GO:0045202"(synapse)|go:"GO:1990932"(5.8S rRNA binding)|interpro:IPR000915(Ribosomal protein L6E)|interpro:IPR005568(Ribosomal protein L6, N-terminal)|interpro:IPR008991(Translation protein SH3-like)|interpro:IPR014722(Translation protein SH3-like, subgroup)|interpro:IPR041997|mint:P21533|reactome:R-RNO-156827|reactome:R-RNO-1799339|reactome:R-RNO-6791226|reactome:R-RNO-72689|reactome:R-RNO-72706|reactome:R-RNO-975956|reactome:R-RNO-975957	-	-	-	figure legend:ST1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10116(rat-brain-cerebellum)|taxid:10116(Rattus norvegicus)	-	2020/10/30	2020/10/30	rogid:DtE+ZXAZKdCMvUW5K+jXQ5bH07M10116	rogid:+Bu8WYfbZdOhyyKpe04yNgrRKkU10116	rigid:OaXQ9NA25fwCWxejPU3Ao9q5j/E	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q5XIE8	uniprotkb:P50878	intact:EBI-15348306|ensembl:ENSRNOP00000023037	intact:EBI-917707	psi-mi:itm2b_rat(display_long)|uniprotkb:Itm2b(gene name)|psi-mi:Itm2b(display_short)|uniprotkb:Immature BRI2(gene name synonym)|uniprotkb:Transmembrane protein BRI(gene name synonym)	psi-mi:rl4_rat(display_long)|uniprotkb:60S ribosomal protein L1(gene name synonym)|uniprotkb:Rpl4(gene name)|psi-mi:Rpl4(display_short)|uniprotkb:Rpl1(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Martins et al. (2018)	imex:IM-28469|pubmed:29476059	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26438079|imex:IM-28469-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSRNOG00000016271(gene)|ensembl:ENSRNOT00000023037(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001540"(amyloid-beta binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0010008"(endosome membrane)|go:"GO:0030660"(Golgi-associated vesicle membrane)|go:"GO:0031301"(integral component of organelle membrane)|go:"GO:0042985"(negative regulation of amyloid precursor protein biosynthetic process)|interpro:IPR007084(BRICHOS)|interpro:IPR040145|mint:Q5XIE8|refseq:NP_001006964.1|rgd:620727	interpro:IPR002136(Ribosomal protein L4/L1e)|interpro:IPR013000(Ribosomal protein L4/L1e, eukaryotic/archaeal, conserved site)|interpro:IPR023574|rgd:619824|refseq:NP_071955.1|mint:P50878|go:"GO:0003360"(brainstem development)|go:"GO:0003723"(RNA binding)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005634"(nucleus)|go:"GO:0005791"(rough endoplasmic reticulum)|go:"GO:0006412"(translation)|go:"GO:0007420"(brain development)|go:"GO:0008097"(5S rRNA binding)|go:"GO:0014069"(postsynaptic density)|go:"GO:0015934"(large ribosomal subunit)|go:"GO:0022625"(cytosolic large ribosomal subunit)|go:"GO:0022626"(cytosolic ribosome)|go:"GO:0030154"(cell differentiation)|go:"GO:0031672"(A band)|go:"GO:0045773"(positive regulation of axon extension)|go:"GO:0050772"(positive regulation of axonogenesis)|go:"GO:0071417"(cellular response to organonitrogen compound)|go:"GO:1990904"(ribonucleoprotein complex)|reactome:R-RNO-156827|reactome:R-RNO-1799339|reactome:R-RNO-6791226|reactome:R-RNO-72689|reactome:R-RNO-72706|reactome:R-RNO-975956|reactome:R-RNO-975957|interpro:IPR025755	-	-	-	figure legend:ST1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10116(rat-brain-cerebellum)|taxid:10116(Rattus norvegicus)	-	2020/10/30	2020/10/30	rogid:DtE+ZXAZKdCMvUW5K+jXQ5bH07M10116	rogid:MBNLNgdqGuXGfOSGP+q3/5Cs9dw10116	rigid:OaXQ9NA25fwCWxejPU3Ao9q5j/E	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q5XIE8	uniprotkb:P41123	intact:EBI-15348306|ensembl:ENSRNOP00000023037	intact:EBI-917471|ensembl:ENSRNOP00000020635	psi-mi:itm2b_rat(display_long)|uniprotkb:Itm2b(gene name)|psi-mi:Itm2b(display_short)|uniprotkb:Immature BRI2(gene name synonym)|uniprotkb:Transmembrane protein BRI(gene name synonym)	psi-mi:rl13_rat(display_long)|uniprotkb:Rpl13(gene name)|psi-mi:Rpl13(display_short)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Martins et al. (2018)	imex:IM-28469|pubmed:29476059	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26438079|imex:IM-28469-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSRNOG00000016271(gene)|ensembl:ENSRNOT00000023037(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001540"(amyloid-beta binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0010008"(endosome membrane)|go:"GO:0030660"(Golgi-associated vesicle membrane)|go:"GO:0031301"(integral component of organelle membrane)|go:"GO:0042985"(negative regulation of amyloid precursor protein biosynthetic process)|interpro:IPR007084(BRICHOS)|interpro:IPR040145|mint:Q5XIE8|refseq:NP_001006964.1|rgd:620727	rgd:621179|refseq:NP_112363.1|ensembl:ENSRNOG00000015335(gene)|ensembl:ENSRNOT00000020635(transcript)|go:"GO:0001824"(blastocyst development)|go:"GO:0003723"(RNA binding)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0006412"(translation)|go:"GO:0022625"(cytosolic large ribosomal subunit)|go:"GO:0022626"(cytosolic ribosome)|go:"GO:0060348"(bone development)|go:"GO:0097421"(liver regeneration)|interpro:IPR001380(Ribosomal protein L13e)|interpro:IPR018256|mint:P41123|reactome:R-RNO-156827|reactome:R-RNO-1799339|reactome:R-RNO-6791226|reactome:R-RNO-72689|reactome:R-RNO-72706|reactome:R-RNO-975956|reactome:R-RNO-975957	-	-	-	figure legend:ST1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10116(rat-brain-cerebellum)|taxid:10116(Rattus norvegicus)	-	2020/10/30	2020/10/30	rogid:DtE+ZXAZKdCMvUW5K+jXQ5bH07M10116	rogid:VaQ1k6Ys24FJswxJBjygrPBW8JE10116	rigid:OaXQ9NA25fwCWxejPU3Ao9q5j/E	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q5XIE8	uniprotkb:P62914	intact:EBI-15348306|ensembl:ENSRNOP00000023037	intact:EBI-438041|ensembl:ENSRNOP00000037110|uniprotkb:P25121|uniprotkb:P39026|uniprotkb:Q9Y674	psi-mi:itm2b_rat(display_long)|uniprotkb:Itm2b(gene name)|psi-mi:Itm2b(display_short)|uniprotkb:Immature BRI2(gene name synonym)|uniprotkb:Transmembrane protein BRI(gene name synonym)	psi-mi:rl11_rat(display_long)|uniprotkb:Rpl11(gene name)|psi-mi:Rpl11(display_short)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Martins et al. (2018)	imex:IM-28469|pubmed:29476059	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26438079|imex:IM-28469-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSRNOG00000016271(gene)|ensembl:ENSRNOT00000023037(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001540"(amyloid-beta binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0010008"(endosome membrane)|go:"GO:0030660"(Golgi-associated vesicle membrane)|go:"GO:0031301"(integral component of organelle membrane)|go:"GO:0042985"(negative regulation of amyloid precursor protein biosynthetic process)|interpro:IPR007084(BRICHOS)|interpro:IPR040145|mint:Q5XIE8|refseq:NP_001006964.1|rgd:620727	ensembl:ENSRNOG00000026260(gene)|ensembl:ENSRNOT00000030043(transcript)|go:"GO:0000027"(ribosomal large subunit assembly)|go:"GO:0002181"(cytoplasmic translation)|go:"GO:0003723"(RNA binding)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006364"(rRNA processing)|go:"GO:0006605"(protein targeting)|go:"GO:0008097"(5S rRNA binding)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0022625"(cytosolic large ribosomal subunit)|go:"GO:0022626"(cytosolic ribosome)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032092"(positive regulation of protein binding)|go:"GO:0032435"(negative regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034504"(protein localization to nucleus)|go:"GO:0042273"(ribosomal large subunit biogenesis)|go:"GO:0042788"(polysomal ribosome)|go:"GO:0042975"(peroxisome proliferator activated receptor binding)|go:"GO:0043433"(negative regulation of DNA-binding transcription factor activity)|go:"GO:0045202"(synapse)|go:"GO:0050821"(protein stabilization)|go:"GO:1901796"(regulation of signal transduction by p53 class mediator)|go:"GO:1901798"(positive regulation of signal transduction by p53 class mediator)|go:"GO:1902255"(positive regulation of intrinsic apoptotic signaling pathway by p53 class mediator)|go:"GO:1904667"(negative regulation of ubiquitin protein ligase activity)|go:"GO:1990948"(ubiquitin ligase inhibitor activity)|go:"GO:2000059"(negative regulation of ubiquitin-dependent protein catabolic process)|go:"GO:2000435"(negative regulation of protein neddylation)|interpro:IPR002132(Ribosomal protein L5)|interpro:IPR020929|interpro:IPR022803|interpro:IPR031309|interpro:IPR031310|mint:P62914|reactome:R-RNO-156827|reactome:R-RNO-1799339|reactome:R-RNO-6791226|reactome:R-RNO-72689|reactome:R-RNO-72706|reactome:R-RNO-975956|reactome:R-RNO-975957|rgd:1308681|refseq:XP_006239286.1	-	-	-	figure legend:ST1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10116(rat-brain-cerebellum)|taxid:10116(Rattus norvegicus)	-	2020/10/30	2020/10/30	rogid:DtE+ZXAZKdCMvUW5K+jXQ5bH07M10116	rogid:xt8XhDkfQPoH4DIPr0gC+ll766Q10116	rigid:OaXQ9NA25fwCWxejPU3Ao9q5j/E	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q5XIE8	uniprotkb:P62083	intact:EBI-15348306|ensembl:ENSRNOP00000023037	intact:EBI-354370|uniprotkb:P24818|uniprotkb:P23821|ensembl:ENSRNOP00000011333|ensembl:ENSRNOP00000075995	psi-mi:itm2b_rat(display_long)|uniprotkb:Itm2b(gene name)|psi-mi:Itm2b(display_short)|uniprotkb:Immature BRI2(gene name synonym)|uniprotkb:Transmembrane protein BRI(gene name synonym)	psi-mi:rs7_rat(display_long)|uniprotkb:Rps7(gene name)|psi-mi:Rps7(display_short)|uniprotkb:S8(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Martins et al. (2018)	imex:IM-28469|pubmed:29476059	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26438079|imex:IM-28469-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSRNOG00000016271(gene)|ensembl:ENSRNOT00000023037(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001540"(amyloid-beta binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0010008"(endosome membrane)|go:"GO:0030660"(Golgi-associated vesicle membrane)|go:"GO:0031301"(integral component of organelle membrane)|go:"GO:0042985"(negative regulation of amyloid precursor protein biosynthetic process)|interpro:IPR007084(BRICHOS)|interpro:IPR040145|mint:Q5XIE8|refseq:NP_001006964.1|rgd:620727	refseq:NP_113758.2|refseq:XP_002726666.2|refseq:XP_002729622.2|rgd:61907|ensembl:ENSRNOG00000008551(gene)|ensembl:ENSRNOT00000011333(transcript)|ensembl:ENSRNOT00000092867(transcript)|go:"GO:0001843"(neural tube closure)|go:"GO:0003730"(mRNA 3'-UTR binding)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005634"(nucleus)|go:"GO:0005730"(nucleolus)|go:"GO:0005815"(microtubule organizing center)|go:"GO:0006364"(rRNA processing)|go:"GO:0008266"("poly(U) RNA binding")|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0019901"(protein kinase binding)|go:"GO:0022626"(cytosolic ribosome)|go:"GO:0022627"(cytosolic small ribosomal subunit)|go:"GO:0030154"(cell differentiation)|go:"GO:0032040"(small-subunit processome)|go:"GO:0032991"(protein-containing complex)|go:"GO:0042274"(ribosomal small subunit biogenesis)|go:"GO:0045202"(synapse)|go:"GO:0048027"(mRNA 5'-UTR binding)|go:"GO:0050821"(protein stabilization)|go:"GO:1902255"(positive regulation of intrinsic apoptotic signaling pathway by p53 class mediator)|go:"GO:1904667"(negative regulation of ubiquitin protein ligase activity)|go:"GO:1990904"(ribonucleoprotein complex)|go:"GO:1990948"(ubiquitin ligase inhibitor activity)|go:"GO:2000059"(negative regulation of ubiquitin-dependent protein catabolic process)|interpro:IPR000554(Ribosomal protein S7e)|mint:P62083|reactome:R-RNO-156827|reactome:R-RNO-1799339|reactome:R-RNO-6791226|reactome:R-RNO-72649|reactome:R-RNO-72689|reactome:R-RNO-72695|reactome:R-RNO-72702|reactome:R-RNO-72706|reactome:R-RNO-975956|reactome:R-RNO-975957|go:"GO:0006412"(translation)	-	-	-	figure legend:ST1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10116(rat-brain-cerebellum)|taxid:10116(Rattus norvegicus)	-	2020/10/30	2020/10/30	rogid:DtE+ZXAZKdCMvUW5K+jXQ5bH07M10116	rogid:l4aG6I34lmzYhNapbdv2CAAwRwg10116	rigid:OaXQ9NA25fwCWxejPU3Ao9q5j/E	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q5XIE8	uniprotkb:P49242	intact:EBI-15348306|ensembl:ENSRNOP00000023037	intact:EBI-917655|uniprotkb:P33443|ensembl:ENSRNOP00000016329	psi-mi:itm2b_rat(display_long)|uniprotkb:Itm2b(gene name)|psi-mi:Itm2b(display_short)|uniprotkb:Immature BRI2(gene name synonym)|uniprotkb:Transmembrane protein BRI(gene name synonym)	psi-mi:rs3a_rat(display_long)|uniprotkb:V-fos transformation effector protein(gene name synonym)|uniprotkb:Rps3a(gene name)|psi-mi:Rps3a(display_short)|uniprotkb:Fte1(gene name synonym)|uniprotkb:Fte-1(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Martins et al. (2018)	imex:IM-28469|pubmed:29476059	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26438079|imex:IM-28469-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSRNOG00000016271(gene)|ensembl:ENSRNOT00000023037(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001540"(amyloid-beta binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0010008"(endosome membrane)|go:"GO:0030660"(Golgi-associated vesicle membrane)|go:"GO:0031301"(integral component of organelle membrane)|go:"GO:0042985"(negative regulation of amyloid precursor protein biosynthetic process)|interpro:IPR007084(BRICHOS)|interpro:IPR040145|mint:Q5XIE8|refseq:NP_001006964.1|rgd:620727	rgd:62078|refseq:NP_058849.1|ensembl:ENSRNOG00000011893(gene)|ensembl:ENSRNOT00000016329(transcript)|go:"GO:0003729"(mRNA binding)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006412"(translation)|go:"GO:0015935"(small ribosomal subunit)|go:"GO:0022626"(cytosolic ribosome)|go:"GO:0022627"(cytosolic small ribosomal subunit)|go:"GO:0030154"(cell differentiation)|go:"GO:0031369"(translation initiation factor binding)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0045202"(synapse)|go:"GO:0045471"(response to ethanol)|go:"GO:0045727"(positive regulation of translation)|go:"GO:0048027"(mRNA 5'-UTR binding)|go:"GO:0048146"(positive regulation of fibroblast proliferation)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR001593(Ribosomal protein S3Ae)|interpro:IPR018281|interpro:IPR027500|mint:P49242|reactome:R-RNO-156827|reactome:R-RNO-1799339|reactome:R-RNO-6791226|reactome:R-RNO-72649|reactome:R-RNO-72689|reactome:R-RNO-72695|reactome:R-RNO-72702|reactome:R-RNO-72706|reactome:R-RNO-975956|reactome:R-RNO-975957	-	-	-	figure legend:ST1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10116(rat-brain-cerebellum)|taxid:10116(Rattus norvegicus)	-	2020/10/30	2020/10/30	rogid:DtE+ZXAZKdCMvUW5K+jXQ5bH07M10116	rogid:49VqZGeHuN0jq/oCUhMNwhrkVgg10116	rigid:OaXQ9NA25fwCWxejPU3Ao9q5j/E	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q5XIE8	uniprotkb:P62856	intact:EBI-15348306|ensembl:ENSRNOP00000023037	intact:EBI-22252395|uniprotkb:P02383|uniprotkb:P70394|uniprotkb:Q06722	psi-mi:itm2b_rat(display_long)|uniprotkb:Itm2b(gene name)|psi-mi:Itm2b(display_short)|uniprotkb:Immature BRI2(gene name synonym)|uniprotkb:Transmembrane protein BRI(gene name synonym)	psi-mi:rs26_rat(display_long)|uniprotkb:Rps26(gene name)|psi-mi:Rps26(display_short)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Martins et al. (2018)	imex:IM-28469|pubmed:29476059	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26438079|imex:IM-28469-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSRNOG00000016271(gene)|ensembl:ENSRNOT00000023037(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001540"(amyloid-beta binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0010008"(endosome membrane)|go:"GO:0030660"(Golgi-associated vesicle membrane)|go:"GO:0031301"(integral component of organelle membrane)|go:"GO:0042985"(negative regulation of amyloid precursor protein biosynthetic process)|interpro:IPR007084(BRICHOS)|interpro:IPR040145|mint:Q5XIE8|refseq:NP_001006964.1|rgd:620727	go:"GO:0098556"(cytoplasmic side of rough endoplasmic reticulum membrane)|go:"GO:0002181"(cytoplasmic translation)|go:"GO:0003729"(mRNA binding)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0022627"(cytosolic small ribosomal subunit)|go:"GO:0042788"(polysomal ribosome)|mint:P62856|rgd:621044|refseq:NP_037356.1|refseq:XP_002728047.3|refseq:XP_003752685.3|interpro:IPR000892(Ribosomal protein S26e)|interpro:IPR038551	-	-	-	figure legend:ST1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10116(rat-brain-cerebellum)|taxid:10116(Rattus norvegicus)	-	2020/10/30	2020/10/30	rogid:DtE+ZXAZKdCMvUW5K+jXQ5bH07M10116	rogid:bo2ruYMNjjLCMo/kwAWzmlJrrjU10116	rigid:OaXQ9NA25fwCWxejPU3Ao9q5j/E	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q5XIE8	uniprotkb:P62853	intact:EBI-15348306|ensembl:ENSRNOP00000023037	intact:EBI-931961|uniprotkb:P25111|uniprotkb:Q3SYP7	psi-mi:itm2b_rat(display_long)|uniprotkb:Itm2b(gene name)|psi-mi:Itm2b(display_short)|uniprotkb:Immature BRI2(gene name synonym)|uniprotkb:Transmembrane protein BRI(gene name synonym)	psi-mi:rs25_rat(display_long)|uniprotkb:Rps25(gene name)|psi-mi:Rps25(display_short)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Martins et al. (2018)	imex:IM-28469|pubmed:29476059	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26438079|imex:IM-28469-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSRNOG00000016271(gene)|ensembl:ENSRNOT00000023037(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001540"(amyloid-beta binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0010008"(endosome membrane)|go:"GO:0030660"(Golgi-associated vesicle membrane)|go:"GO:0031301"(integral component of organelle membrane)|go:"GO:0042985"(negative regulation of amyloid precursor protein biosynthetic process)|interpro:IPR007084(BRICHOS)|interpro:IPR040145|mint:Q5XIE8|refseq:NP_001006964.1|rgd:620727	rgd:621043|refseq:NP_001005528.1|interpro:IPR004977(Ribosomal protein S25)|mint:P62853|interpro:IPR036388|go:"GO:0000028"(ribosomal small subunit assembly)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005634"(nucleus)|go:"GO:0005730"(nucleolus)|go:"GO:0005840"(ribosome)|go:"GO:0005844"(polysome)|go:"GO:0006364"(rRNA processing)|go:"GO:0014069"(postsynaptic density)|go:"GO:0022626"(cytosolic ribosome)|go:"GO:0022627"(cytosolic small ribosomal subunit)|go:"GO:0034198"(cellular response to amino acid starvation)|go:"GO:0042274"(ribosomal small subunit biogenesis)|go:"GO:0045202"(synapse)|reactome:R-RNO-156827|reactome:R-RNO-1799339|reactome:R-RNO-6791226|reactome:R-RNO-72649|reactome:R-RNO-72689|reactome:R-RNO-72695|reactome:R-RNO-72702|reactome:R-RNO-72706|reactome:R-RNO-975956|reactome:R-RNO-975957	-	-	-	figure legend:ST1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10116(rat-brain-cerebellum)|taxid:10116(Rattus norvegicus)	-	2020/10/30	2020/10/30	rogid:DtE+ZXAZKdCMvUW5K+jXQ5bH07M10116	rogid:7TqA4Q6+6VMzrzaUrACbwtJKfOM10116	rigid:OaXQ9NA25fwCWxejPU3Ao9q5j/E	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q5XIE8	uniprotkb:P60868	intact:EBI-15348306|ensembl:ENSRNOP00000023037	intact:EBI-931416|uniprotkb:P17075|ensembl:ENSRNOP00000065886|ensembl:ENSRNOP00000066077|ensembl:ENSRNOP00000069127	psi-mi:itm2b_rat(display_long)|uniprotkb:Itm2b(gene name)|psi-mi:Itm2b(display_short)|uniprotkb:Immature BRI2(gene name synonym)|uniprotkb:Transmembrane protein BRI(gene name synonym)	psi-mi:rs20_rat(display_long)|uniprotkb:Rps20(gene name)|psi-mi:Rps20(display_short)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Martins et al. (2018)	imex:IM-28469|pubmed:29476059	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26438079|imex:IM-28469-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSRNOG00000016271(gene)|ensembl:ENSRNOT00000023037(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001540"(amyloid-beta binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0010008"(endosome membrane)|go:"GO:0030660"(Golgi-associated vesicle membrane)|go:"GO:0031301"(integral component of organelle membrane)|go:"GO:0042985"(negative regulation of amyloid precursor protein biosynthetic process)|interpro:IPR007084(BRICHOS)|interpro:IPR040145|mint:Q5XIE8|refseq:NP_001006964.1|rgd:620727	rgd:621037|refseq:NP_001007604.1|refseq:XP_002726693.1|refseq:XP_002727194.1|refseq:XP_002729204.1|refseq:XP_002729620.1|refseq:XP_002730040.1|refseq:XP_003753765.1|ensembl:ENSRNOG00000029627(gene)|ensembl:ENSRNOG00000030345(gene)|ensembl:ENSRNOG00000030596(gene)|ensembl:ENSRNOT00000040481(transcript)|ensembl:ENSRNOT00000041813(transcript)|ensembl:ENSRNOT00000051449(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0006412"(translation)|go:"GO:0015935"(small ribosomal subunit)|go:"GO:0022626"(cytosolic ribosome)|go:"GO:0022627"(cytosolic small ribosomal subunit)|go:"GO:0045202"(synapse)|go:"GO:0097371"(MDM2/MDM4 family protein binding)|go:"GO:1901798"(positive regulation of signal transduction by p53 class mediator)|go:"GO:1990948"(ubiquitin ligase inhibitor activity)|interpro:IPR001848(Ribosomal protein S10)|interpro:IPR005729(Ribosomal protein S10, eukaryotic/archaeal)|interpro:IPR018268|interpro:IPR027486|interpro:IPR036838|mint:P60868|reactome:R-RNO-156827|reactome:R-RNO-1799339|reactome:R-RNO-6791226|reactome:R-RNO-72649|reactome:R-RNO-72689|reactome:R-RNO-72695|reactome:R-RNO-72702|reactome:R-RNO-72706|reactome:R-RNO-975956|reactome:R-RNO-975957	-	-	-	figure legend:ST1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10116(rat-brain-cerebellum)|taxid:10116(Rattus norvegicus)	-	2020/10/30	2020/10/30	rogid:DtE+ZXAZKdCMvUW5K+jXQ5bH07M10116	rogid:6xNxX+eP59AOm0KraCysRHUqMFw10116	rigid:OaXQ9NA25fwCWxejPU3Ao9q5j/E	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q5XIE8	uniprotkb:P63326	intact:EBI-15348306|ensembl:ENSRNOP00000023037	intact:EBI-916252|ensembl:ENSRNOP00000043693|uniprotkb:P09900|uniprotkb:Q9DCR5	psi-mi:itm2b_rat(display_long)|uniprotkb:Itm2b(gene name)|psi-mi:Itm2b(display_short)|uniprotkb:Immature BRI2(gene name synonym)|uniprotkb:Transmembrane protein BRI(gene name synonym)	psi-mi:rs10_rat(display_long)|uniprotkb:Rps10(gene name)|psi-mi:Rps10(display_short)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Martins et al. (2018)	imex:IM-28469|pubmed:29476059	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26438079|imex:IM-28469-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSRNOG00000016271(gene)|ensembl:ENSRNOT00000023037(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001540"(amyloid-beta binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0010008"(endosome membrane)|go:"GO:0030660"(Golgi-associated vesicle membrane)|go:"GO:0031301"(integral component of organelle membrane)|go:"GO:0042985"(negative regulation of amyloid precursor protein biosynthetic process)|interpro:IPR007084(BRICHOS)|interpro:IPR040145|mint:Q5XIE8|refseq:NP_001006964.1|rgd:620727	ensembl:ENSRNOG00000052141(gene)|ensembl:ENSRNOT00000043250(transcript)|go:"GO:0000028"(ribosomal small subunit assembly)|go:"GO:0000049"(tRNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005730"(nucleolus)|go:"GO:0022626"(cytosolic ribosome)|go:"GO:0022627"(cytosolic small ribosomal subunit)|interpro:IPR005326(Plectin/S10, N-terminal)|interpro:IPR036388|interpro:IPR037447|mint:P63326|reactome:R-RNO-156827|reactome:R-RNO-1799339|reactome:R-RNO-6791226|reactome:R-RNO-72649|reactome:R-RNO-72689|reactome:R-RNO-72695|reactome:R-RNO-72702|reactome:R-RNO-72706|reactome:R-RNO-975956|reactome:R-RNO-975957|refseq:XP_003754221.1|rgd:621024|refseq:NP_112371.1|refseq:XP_002729669.1	-	-	-	figure legend:ST1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10116(rat-brain-cerebellum)|taxid:10116(Rattus norvegicus)	-	2020/10/30	2020/10/30	rogid:DtE+ZXAZKdCMvUW5K+jXQ5bH07M10116	rogid:XN7SjnIc8XsuJiY6/WulloSN//010116	rigid:OaXQ9NA25fwCWxejPU3Ao9q5j/E	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q5XIE8	uniprotkb:P63102	intact:EBI-15348306|ensembl:ENSRNOP00000023037	intact:EBI-354758|uniprotkb:P35215|uniprotkb:P70197|uniprotkb:P97286|uniprotkb:Q52KK1|uniprotkb:Q6IRF4|ensembl:ENSRNOP00000030885	psi-mi:itm2b_rat(display_long)|uniprotkb:Itm2b(gene name)|psi-mi:Itm2b(display_short)|uniprotkb:Immature BRI2(gene name synonym)|uniprotkb:Transmembrane protein BRI(gene name synonym)	psi-mi:1433z_rat(display_long)|uniprotkb:Ywhaz(gene name)|psi-mi:Ywhaz(display_short)|uniprotkb:Msfs1(gene name synonym)|uniprotkb:Protein kinase C inhibitor protein 1(gene name synonym)|uniprotkb:Mitochondrial import stimulation factor S1 subunit(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Martins et al. (2018)	imex:IM-28469|pubmed:29476059	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26438079|imex:IM-28469-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSRNOG00000016271(gene)|ensembl:ENSRNOT00000023037(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001540"(amyloid-beta binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0010008"(endosome membrane)|go:"GO:0030660"(Golgi-associated vesicle membrane)|go:"GO:0031301"(integral component of organelle membrane)|go:"GO:0042985"(negative regulation of amyloid precursor protein biosynthetic process)|interpro:IPR007084(BRICHOS)|interpro:IPR040145|mint:Q5XIE8|refseq:NP_001006964.1|rgd:620727	rgd:3980|refseq:NP_037143.2|go:"GO:0019901"(protein kinase binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030324"(lung development)|go:"GO:0031252"(cell leading edge)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035148"(tube formation)|go:"GO:0042470"(melanosome)|go:"GO:0042493"|go:"GO:0042802"(identical protein binding)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051683"(establishment of Golgi localization)|go:"GO:0070371"(ERK1 and ERK2 cascade)|go:"GO:0070372"(regulation of ERK1 and ERK2 cascade)|go:"GO:0090128"(regulation of synapse maturation)|go:"GO:0090168"(Golgi reassembly)|go:"GO:0098686"(hippocampal mossy fiber to CA3 synapse)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0140297"(DNA-binding transcription factor binding)|interpro:IPR000308(14-3-3 protein)|interpro:IPR023409|interpro:IPR023410|interpro:IPR036815|mint:P63102|reactome:R-RNO-111447|reactome:R-RNO-3769402|reactome:R-RNO-392517|reactome:R-RNO-430116|reactome:R-RNO-450604|reactome:R-RNO-512988|reactome:R-RNO-5625740|reactome:R-RNO-5628897|reactome:R-RNO-75035|reactome:R-RNO-9013700|reactome:R-RNO-9614399|refseq:XP_006241591.1|ensembl:ENSRNOG00000008195(gene)|ensembl:ENSRNOT00000035628(transcript)|go:"GO:0001525"(angiogenesis)|go:"GO:0002553"(histamine secretion by mast cell)|go:"GO:0003016"(respiratory system process)|go:"GO:0005634"(nucleus)|go:"GO:0005739"(mitochondrion)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0006605"(protein targeting)|go:"GO:0006626"(protein targeting to mitochondrion)|go:"GO:0007165"(signal transduction)|go:"GO:0008039"(synaptic target recognition)|go:"GO:0010941"(regulation of cell death)|go:"GO:0014069"(postsynaptic density)|dip:DIP-36916N	-	-	-	figure legend:ST1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10116(rat-brain-cerebellum)|taxid:10116(Rattus norvegicus)	-	2020/10/30	2020/10/30	rogid:DtE+ZXAZKdCMvUW5K+jXQ5bH07M10116	rogid:v2N95HO8sYRWEg2gFtWiYajP1Sc10116	rigid:OaXQ9NA25fwCWxejPU3Ao9q5j/E	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q5XIE8	uniprotkb:Q5XI81	intact:EBI-15348306|ensembl:ENSRNOP00000023037	intact:EBI-21997101	psi-mi:itm2b_rat(display_long)|uniprotkb:Itm2b(gene name)|psi-mi:Itm2b(display_short)|uniprotkb:Immature BRI2(gene name synonym)|uniprotkb:Transmembrane protein BRI(gene name synonym)	psi-mi:fxr1_rat(display_long)|uniprotkb:Fxr1(gene name)|psi-mi:Fxr1(display_short)|uniprotkb:Fxr1h(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Martins et al. (2018)	imex:IM-28469|pubmed:29476059	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26438079|imex:IM-28469-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSRNOG00000016271(gene)|ensembl:ENSRNOT00000023037(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001540"(amyloid-beta binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0010008"(endosome membrane)|go:"GO:0030660"(Golgi-associated vesicle membrane)|go:"GO:0031301"(integral component of organelle membrane)|go:"GO:0042985"(negative regulation of amyloid precursor protein biosynthetic process)|interpro:IPR007084(BRICHOS)|interpro:IPR040145|mint:Q5XIE8|refseq:NP_001006964.1|rgd:620727	rgd:1311733|refseq:NP_001012179.1|interpro:IPR008395(Agenet)|interpro:IPR040148|interpro:IPR040472|interpro:IPR022034|interpro:IPR032172|interpro:IPR004087(K Homology)|interpro:IPR004088(K Homology, type 1)|interpro:IPR036612|interpro:IPR041560|mint:Q5XI81|go:"GO:0000381"(regulation of alternative mRNA splicing, via spliceosome)|go:"GO:0001934"(positive regulation of protein phosphorylation)|go:"GO:0003730"(mRNA 3'-UTR binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005844"(polysome)|go:"GO:0007517"(muscle organ development)|go:"GO:0014069"(postsynaptic density)|go:"GO:0016020"(membrane)|go:"GO:0017148"(negative regulation of translation)|go:"GO:0030154"(cell differentiation)|go:"GO:0030424"(axon)|go:"GO:0030425"(dendrite)|go:"GO:0030426"(growth cone)|go:"GO:0033592"(RNA strand annealing activity)|go:"GO:0035770"(ribonucleoprotein granule)|go:"GO:0036464"(cytoplasmic ribonucleoprotein granule)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043034"(costamere)|go:"GO:0043197"(dendritic spine)|go:"GO:0043488"(regulation of mRNA stability)|go:"GO:0044326"(dendritic spine neck)|go:"GO:0045182"(translation regulator activity)|go:"GO:0045727"(positive regulation of translation)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051489"(regulation of filopodium assembly)|go:"GO:0060538"(skeletal muscle organ development)|go:"GO:0098793"(presynapse)|go:"GO:0098794"(postsynapse)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:1902737"(dendritic filopodium)|go:"GO:2000637"(positive regulation of gene silencing by miRNA)|go:"GO:2001022"(positive regulation of response to DNA damage stimulus)	-	-	-	figure legend:ST1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10116(rat-brain-cerebellum)|taxid:10116(Rattus norvegicus)	-	2020/10/30	2020/10/30	rogid:DtE+ZXAZKdCMvUW5K+jXQ5bH07M10116	rogid:TVgcYLrOuzdkgi/9hAiwGP0ILZo10116	rigid:OaXQ9NA25fwCWxejPU3Ao9q5j/E	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q5XIE8	uniprotkb:Q63633	intact:EBI-15348306|ensembl:ENSRNOP00000023037	intact:EBI-1811510|uniprotkb:A7Y821	psi-mi:itm2b_rat(display_long)|uniprotkb:Itm2b(gene name)|psi-mi:Itm2b(display_short)|uniprotkb:Immature BRI2(gene name synonym)|uniprotkb:Transmembrane protein BRI(gene name synonym)	psi-mi:s12a5_rat(display_long)|uniprotkb:Slc12a5(gene name)|psi-mi:Slc12a5(display_short)|uniprotkb:Kcc2(gene name synonym)|uniprotkb:Electroneutral potassium-chloride cotransporter 2(gene name synonym)|uniprotkb:K-Cl cotransporter 2(gene name synonym)|uniprotkb:Neuronal K-Cl cotransporter(gene name synonym)|uniprotkb:Furosemide-sensitive K-Cl cotransporter(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Martins et al. (2018)	imex:IM-28469|pubmed:29476059	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26440627|imex:IM-28469-5	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSRNOG00000016271(gene)|ensembl:ENSRNOT00000023037(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001540"(amyloid-beta binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0010008"(endosome membrane)|go:"GO:0030660"(Golgi-associated vesicle membrane)|go:"GO:0031301"(integral component of organelle membrane)|go:"GO:0042985"(negative regulation of amyloid precursor protein biosynthetic process)|interpro:IPR007084(BRICHOS)|interpro:IPR040145|mint:Q5XIE8|refseq:NP_001006964.1|rgd:620727	interpro:IPR004842(Na-K-Cl cotransporter superfamily)|rgd:620811|refseq:NP_599190.1|interpro:IPR004841(Amino acid permease-associated region)|interpro:IPR000076(K-Cl co-transporter)|interpro:IPR030358|mint:Q63633|interpro:IPR018491|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006811"(ion transport)|go:"GO:0006813"(potassium ion transport)|go:"GO:0006821"(chloride transport)|go:"GO:0006873"(cellular ion homeostasis)|go:"GO:0006884"(cell volume homeostasis)|go:"GO:0006971"(hypotonic response)|go:"GO:0007268"(chemical synaptic transmission)|go:"GO:0007612"(learning)|go:"GO:0008519"(ammonium transmembrane transporter activity)|go:"GO:0015108"(chloride transmembrane transporter activity)|go:"GO:0015379"("potassium:chloride symporter activity")|go:"GO:0015696"|go:"GO:0016021"(integral component of membrane)|go:"GO:0030644"(cellular chloride ion homeostasis)|go:"GO:0032590"(dendrite membrane)|go:"GO:0035264"(multicellular organism growth)|go:"GO:0040040"(thermosensory behavior)|go:"GO:0042493"|go:"GO:0043005"(neuron projection)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043204"(perikaryon)|go:"GO:0045202"(synapse)|go:"GO:0051452"(intracellular pH reduction)|go:"GO:0055064"(chloride ion homeostasis)|go:"GO:0055075"(potassium ion homeostasis)|go:"GO:0060996"(dendritic spine development)|go:"GO:0071944"(cell periphery)|go:"GO:1902476"(chloride transmembrane transport)|go:"GO:1990573"(potassium ion import across plasma membrane)|reactome:R-RNO-426117	-	-	-	figure legend:st1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10116(rat-hippocampus)|taxid:10116(Rattus norvegicus hippocampal neurons)	-	2020/10/30	2020/10/30	rogid:DtE+ZXAZKdCMvUW5K+jXQ5bH07M10116	rogid:re2eaKJoJFpp2Gk1MowLaTa+NYU10116	rigid:zzsc1zNhBb5nwIRPeFpYOKgC3M8	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q5XIE8	uniprotkb:Q62910	intact:EBI-15348306|ensembl:ENSRNOP00000023037	intact:EBI-1149123|uniprotkb:O89092|uniprotkb:Q62911|uniprotkb:Q810Z8|ensembl:ENSRNOP00000060346	psi-mi:itm2b_rat(display_long)|uniprotkb:Itm2b(gene name)|psi-mi:Itm2b(display_short)|uniprotkb:Immature BRI2(gene name synonym)|uniprotkb:Transmembrane protein BRI(gene name synonym)	psi-mi:synj1_rat(display_long)|uniprotkb:Synj1(gene name)|psi-mi:Synj1(display_short)|uniprotkb:Synaptic inositol 1,4,5-trisphosphate 5-phosphatase 1(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Martins et al. (2018)	imex:IM-28469|pubmed:29476059	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26440627|imex:IM-28469-5	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSRNOG00000016271(gene)|ensembl:ENSRNOT00000023037(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001540"(amyloid-beta binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0010008"(endosome membrane)|go:"GO:0030660"(Golgi-associated vesicle membrane)|go:"GO:0031301"(integral component of organelle membrane)|go:"GO:0042985"(negative regulation of amyloid precursor protein biosynthetic process)|interpro:IPR007084(BRICHOS)|interpro:IPR040145|mint:Q5XIE8|refseq:NP_001006964.1|rgd:620727	rgd:69434|refseq:NP_445928.2|ensembl:ENSRNOG00000002051(gene)|ensembl:ENSRNOT00000065535(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0004438"(phosphatidylinositol-3-phosphatase activity)|go:"GO:0004439"(phosphatidylinositol-4,5-bisphosphate 5-phosphatase activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0006836"(neurotransmitter transport)|go:"GO:0007420"(brain development)|go:"GO:0007612"(learning)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0012506"(vesicle membrane)|go:"GO:0014015"(positive regulation of gliogenesis)|go:"GO:0016082"(synaptic vesicle priming)|go:"GO:0016191"(synaptic vesicle uncoating)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0030117"(membrane coat)|go:"GO:0030132"(clathrin coat of coated pit)|go:"GO:0032526"(response to retinoic acid)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034097"(response to cytokine)|go:"GO:0034595"(phosphatidylinositol phosphate 5-phosphatase activity)|go:"GO:0043005"(neuron projection)|go:"GO:0043195"(terminal bouton)|go:"GO:0043812"(phosphatidylinositol-4-phosphate phosphatase activity)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0046488"(phosphatidylinositol metabolic process)|go:"GO:0046855"(inositol phosphate dephosphorylation)|go:"GO:0046856"(phosphatidylinositol dephosphorylation)|go:"GO:0048260"(positive regulation of receptor-mediated endocytosis)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0048488"(synaptic vesicle endocytosis)|go:"GO:0048489"(synaptic vesicle transport)|go:"GO:0052658"(inositol-1,4,5-trisphosphate 5-phosphatase activity)|go:"GO:0097060"(synaptic membrane)|go:"GO:0098685"(Schaffer collateral - CA1 synapse)|go:"GO:0098688"(parallel fiber to Purkinje cell synapse)|go:"GO:0098793"(presynapse)|go:"GO:0098794"(postsynapse)|go:"GO:0098884"(postsynaptic neurotransmitter receptor internalization)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099149"(regulation of postsynaptic neurotransmitter receptor internalization)|go:"GO:1904980"(positive regulation of endosome organization)|go:"GO:1990175"(EH domain binding)|interpro:IPR000300(Inositol polyphosphate related phosphatase)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR002013(Synaptojanin, N-terminal)|interpro:IPR005135(Endonuclease/exonuclease/phosphatase)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR015047(Region of unknown function DUF1866)|interpro:IPR034971|interpro:IPR034972|interpro:IPR035979|interpro:IPR036691|mint:Q62910|reactome:R-RNO-1660499|reactome:R-RNO-1855183|reactome:R-RNO-1855204|reactome:R-RNO-8856828	-	-	-	figure legend:st1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10116(rat-hippocampus)|taxid:10116(Rattus norvegicus hippocampal neurons)	-	2020/10/30	2020/10/30	rogid:DtE+ZXAZKdCMvUW5K+jXQ5bH07M10116	rogid:EJnYHctzzxfhvA7evwx+c2HKuIE10116	rigid:zzsc1zNhBb5nwIRPeFpYOKgC3M8	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q5XIE8	uniprotkb:P52873	intact:EBI-15348306|ensembl:ENSRNOP00000023037	intact:EBI-7623445|intact:MINT-4592965|uniprotkb:Q5RKM0|uniprotkb:Q64555|ensembl:ENSRNOP00000026316|ensembl:ENSRNOP00000075317	psi-mi:itm2b_rat(display_long)|uniprotkb:Itm2b(gene name)|psi-mi:Itm2b(display_short)|uniprotkb:Immature BRI2(gene name synonym)|uniprotkb:Transmembrane protein BRI(gene name synonym)	psi-mi:pyc_rat(display_long)|uniprotkb:Pc(gene name)|psi-mi:Pc(display_short)|uniprotkb:Pyruvic carboxylase(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Martins et al. (2018)	imex:IM-28469|pubmed:29476059	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26440627|imex:IM-28469-5	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSRNOG00000016271(gene)|ensembl:ENSRNOT00000023037(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001540"(amyloid-beta binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0010008"(endosome membrane)|go:"GO:0030660"(Golgi-associated vesicle membrane)|go:"GO:0031301"(integral component of organelle membrane)|go:"GO:0042985"(negative regulation of amyloid precursor protein biosynthetic process)|interpro:IPR007084(BRICHOS)|interpro:IPR040145|mint:Q5XIE8|refseq:NP_001006964.1|rgd:620727	refseq:NP_036876.2|rgd:3262|ensembl:ENSRNOT00000026316(transcript)|ensembl:ENSRNOT00000082388(transcript)|go:"GO:0004736"(pyruvate carboxylase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0006090"(pyruvate metabolic process)|go:"GO:0006094"(gluconeogenesis)|go:"GO:0006107"(oxaloacetate metabolic process)|go:"GO:0006629"(lipid metabolic process)|go:"GO:0009374"(biotin binding)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0019074"(viral RNA genome packaging)|go:"GO:0031406"(carboxylic acid binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0044791"(obsolete positive regulation by host of viral release from host cell)|go:"GO:0044794"(positive regulation by host of viral process)|go:"GO:0046872"(metal ion binding)|go:"GO:0071073"(positive regulation of phospholipid biosynthetic process)|interpro:IPR000089(Biotin/lipoyl attachment)|interpro:IPR000891(Pyruvate carboxyltransferase)|interpro:IPR001882(Biotin-binding site)|interpro:IPR003379(Conserved carboxylase region)|interpro:IPR005479(Carbamoyl phosphate synthetase, large subunit, ATP-binding)|interpro:IPR005481(Carbamoyl phosphate synthase, large subunit, N-terminal)|interpro:IPR005482(Biotin carboxylase, C-terminal)|interpro:IPR005930(Pyruvate carboxylase)|interpro:IPR011053(Single hybrid motif)|ensembl:ENSRNOG00000019372(gene)|interpro:IPR011054(Rudiment single hybrid motif)|interpro:IPR011761(ATP-grasp fold)|interpro:IPR011764(Biotin carboxylation region)|interpro:IPR013815(ATP-grasp fold, subdomain 1)|interpro:IPR016185(PreATP-grasp-like fold)|mint:P52873|reactome:R-RNO-196780|reactome:R-RNO-70263|interpro:IPR013785(Aldolase-type TIM barrel)|refseq:XP_006230754.1|refseq:XP_006230755.1|refseq:XP_006230756.1	-	-	function:"Pyruvate carboxylase catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second. Catalyzes in a tissue specific manner, the initial reactions of glucose (liver, kidney) and lipid (adipose tissue, liver, brain) synthesis from pyruvate"|comment:mint	figure legend:st1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10116(rat-hippocampus)|taxid:10116(Rattus norvegicus hippocampal neurons)	-	2020/10/30	2020/10/30	rogid:DtE+ZXAZKdCMvUW5K+jXQ5bH07M10116	rogid:ETBFyZy4Cg5F4LC5eBHHHCzTkKY10116	rigid:zzsc1zNhBb5nwIRPeFpYOKgC3M8	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q5XIE8	uniprotkb:P54287	intact:EBI-15348306|ensembl:ENSRNOP00000023037	intact:EBI-8028596|intact:MINT-8407486|ensembl:ENSRNOP00000073026	psi-mi:itm2b_rat(display_long)|uniprotkb:Itm2b(gene name)|psi-mi:Itm2b(display_short)|uniprotkb:Immature BRI2(gene name synonym)|uniprotkb:Transmembrane protein BRI(gene name synonym)	psi-mi:cacb3_rat(display_long)|uniprotkb:Cacnb3(gene name)|psi-mi:Cacnb3(display_short)|uniprotkb:Cacnlb3(gene name synonym)|uniprotkb:Calcium channel voltage-dependent subunit beta 3(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Martins et al. (2018)	imex:IM-28469|pubmed:29476059	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26440627|imex:IM-28469-5	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSRNOG00000016271(gene)|ensembl:ENSRNOT00000023037(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001540"(amyloid-beta binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0010008"(endosome membrane)|go:"GO:0030660"(Golgi-associated vesicle membrane)|go:"GO:0031301"(integral component of organelle membrane)|go:"GO:0042985"(negative regulation of amyloid precursor protein biosynthetic process)|interpro:IPR007084(BRICHOS)|interpro:IPR040145|mint:Q5XIE8|refseq:NP_001006964.1|rgd:620727	refseq:NP_036960.1|rgd:2248|dip:DIP-59370N|ensembl:ENSRNOG00000054274(gene)|ensembl:ENSRNOT00000081206(transcript)|go:"GO:0005245"(voltage-gated calcium channel activity)|go:"GO:0005246"(calcium channel regulator activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005891"(voltage-gated calcium channel complex)|go:"GO:0006816"(calcium ion transport)|go:"GO:0007268"(chemical synaptic transmission)|go:"GO:0007528"(neuromuscular junction development)|go:"GO:0016020"(membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0019901"(protein kinase binding)|go:"GO:0045202"(synapse)|go:"GO:0050852"(T cell receptor signaling pathway)|go:"GO:0050966"(detection of mechanical stimulus involved in sensory perception of pain)|go:"GO:0060402"(calcium ion transport into cytosol)|go:"GO:0061577"(calcium ion transmembrane transport via high voltage-gated calcium channel)|go:"GO:0070588"(calcium ion transmembrane transport)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0090314"(positive regulation of protein targeting to membrane)|go:"GO:0090650"(cellular response to oxygen-glucose deprivation)|go:"GO:0098903"(regulation of membrane repolarization during action potential)|go:"GO:1901385"(regulation of voltage-gated calcium channel activity)|go:"GO:1901386"(negative regulation of voltage-gated calcium channel activity)|go:"GO:1901387"(positive regulation of voltage-gated calcium channel activity)|go:"GO:1901843"(positive regulation of high voltage-gated calcium channel activity)|go:"GO:1902630"(regulation of membrane hyperpolarization)|go:"GO:1905788"(negative regulation of detection of mechanical stimulus involved in sensory perception of touch)|go:"GO:1990454"(L-type voltage-gated calcium channel complex)|go:"GO:2000463"(positive regulation of excitatory postsynaptic potential)|interpro:IPR000584(Voltage-dependent calcium channel, L-type, beta subunit)|interpro:IPR001452(Src homology-3)|interpro:IPR008079(Voltage-dependent calcium channel, L-type, beta-3 subunit)|interpro:IPR008145(Guanylate kinase/L-type calcium channel region)|interpro:IPR027417|interpro:IPR035760|interpro:IPR036028|mint:P54287|rcsb pdb:1VYT|rcsb pdb:1VYU|reactome:R-RNO-112308|reactome:R-RNO-422356	-	-	comment:mint	figure legend:st1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10116(rat-hippocampus)|taxid:10116(Rattus norvegicus hippocampal neurons)	-	2020/10/30	2020/10/30	rogid:DtE+ZXAZKdCMvUW5K+jXQ5bH07M10116	rogid:qioxo4m/B/2M8vhhTS2urRHOmO010116	rigid:zzsc1zNhBb5nwIRPeFpYOKgC3M8	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q5XIE8	uniprotkb:P16617	intact:EBI-15348306|ensembl:ENSRNOP00000023037	intact:EBI-6998149|ensembl:ENSRNOP00000073523|uniprotkb:Q5M945|intact:MINT-4577521|uniprotkb:Q6P508	psi-mi:itm2b_rat(display_long)|uniprotkb:Itm2b(gene name)|psi-mi:Itm2b(display_short)|uniprotkb:Immature BRI2(gene name synonym)|uniprotkb:Transmembrane protein BRI(gene name synonym)	psi-mi:pgk1_rat(display_long)|uniprotkb:Pgk1(gene name)|psi-mi:Pgk1(display_short)|uniprotkb:Pgk-1(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Martins et al. (2018)	imex:IM-28469|pubmed:29476059	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26440627|imex:IM-28469-5	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSRNOG00000016271(gene)|ensembl:ENSRNOT00000023037(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001540"(amyloid-beta binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0010008"(endosome membrane)|go:"GO:0030660"(Golgi-associated vesicle membrane)|go:"GO:0031301"(integral component of organelle membrane)|go:"GO:0042985"(negative regulation of amyloid precursor protein biosynthetic process)|interpro:IPR007084(BRICHOS)|interpro:IPR040145|mint:Q5XIE8|refseq:NP_001006964.1|rgd:620727	ensembl:ENSRNOG00000058249(gene)|ensembl:ENSRNOT00000077604(transcript)|go:"GO:0004618"(phosphoglycerate kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005829"(cytosol)|go:"GO:0005975"(carbohydrate metabolic process)|go:"GO:0006094"(gluconeogenesis)|go:"GO:0006096"(glycolytic process)|go:"GO:0016310"(phosphorylation)|go:"GO:0016525"(negative regulation of angiogenesis)|go:"GO:0030855"(epithelial cell differentiation)|go:"GO:0031639"(plasminogen activation)|go:"GO:0043531"(ADP binding)|go:"GO:0045121"(membrane raft)|go:"GO:0047134"("protein-disulfide reductase (NAD(P)) activity")|go:"GO:0071456"(cellular response to hypoxia)|interpro:IPR001576(Phosphoglycerate kinase)|interpro:IPR015824(Phosphoglycerate kinase, N-terminal)|interpro:IPR015911(Phosphoglycerate kinase, conserved site)|interpro:IPR036043|mint:P16617|reactome:R-RNO-70171|reactome:R-RNO-70263|rgd:619878|refseq:NP_445743.2	-	-	comment:mint	figure legend:st1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10116(rat-hippocampus)|taxid:10116(Rattus norvegicus hippocampal neurons)	-	2020/10/30	2020/10/30	rogid:DtE+ZXAZKdCMvUW5K+jXQ5bH07M10116	rogid:I0SENiOo0xlTh4aYi7EmTRQ+wCY10116	rigid:zzsc1zNhBb5nwIRPeFpYOKgC3M8	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q5XIE8	uniprotkb:Q62950	intact:EBI-15348306|ensembl:ENSRNOP00000023037	intact:EBI-7109419|ensembl:ENSRNOP00000063671|uniprotkb:P70546|intact:MINT-4051102	psi-mi:itm2b_rat(display_long)|uniprotkb:Itm2b(gene name)|psi-mi:Itm2b(display_short)|uniprotkb:Immature BRI2(gene name synonym)|uniprotkb:Transmembrane protein BRI(gene name synonym)	psi-mi:dpyl1_rat(display_long)|uniprotkb:Crmp1(gene name)|psi-mi:Crmp1(display_short)|uniprotkb:Dpysl1(gene name synonym)|uniprotkb:Collapsin response mediator protein 1(gene name synonym)|uniprotkb:Inactive dihydropyrimidinase(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Martins et al. (2018)	imex:IM-28469|pubmed:29476059	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26440627|imex:IM-28469-5	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSRNOG00000016271(gene)|ensembl:ENSRNOT00000023037(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001540"(amyloid-beta binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0010008"(endosome membrane)|go:"GO:0030660"(Golgi-associated vesicle membrane)|go:"GO:0031301"(integral component of organelle membrane)|go:"GO:0042985"(negative regulation of amyloid precursor protein biosynthetic process)|interpro:IPR007084(BRICHOS)|interpro:IPR040145|mint:Q5XIE8|refseq:NP_001006964.1|rgd:620727	ensembl:ENSRNOG00000004781(gene)|ensembl:ENSRNOT00000065334(transcript)|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005819"(spindle)|go:"GO:0005829"(cytosol)|go:"GO:0007411"(axon guidance)|go:"GO:0010977"(negative regulation of neuron projection development)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0016810"("hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds")|go:"GO:0030425"(dendrite)|go:"GO:0030426"(growth cone)|go:"GO:0030496"(midbody)|go:"GO:0031005"(filamin binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043204"(perikaryon)|go:"GO:0048666"(neuron development)|go:"GO:0051219"(phosphoprotein binding)|go:"GO:0071526"(semaphorin-plexin signaling pathway)|go:"GO:1904530"(negative regulation of actin filament binding)|interpro:IPR006680(Amidohydrolase 1)|interpro:IPR011059(Metal-dependent hydrolase, composite)|interpro:IPR011778(D-hydantoinase)|interpro:IPR030624|interpro:IPR032466|mint:Q62950|reactome:R-RNO-399956|refseq:NP_037064.1|rgd:2407	-	-	function:Necessary for signaling by class 3 semaphorins and subsequent remodeling of the cytoskeleton. Plays a role in axon guidance, invasive growth and cell migration|comment:mint	figure legend:st1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10116(rat-hippocampus)|taxid:10116(Rattus norvegicus hippocampal neurons)	-	2020/10/30	2020/10/30	rogid:DtE+ZXAZKdCMvUW5K+jXQ5bH07M10116	rogid:7low1NeCgJsFO6tv/Jic3nBec4g10116	rigid:zzsc1zNhBb5nwIRPeFpYOKgC3M8	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q5XIE8	uniprotkb:Q6QLM7	intact:EBI-15348306|ensembl:ENSRNOP00000023037	intact:EBI-8053424|intact:UNK-5485260	psi-mi:itm2b_rat(display_long)|uniprotkb:Itm2b(gene name)|psi-mi:Itm2b(display_short)|uniprotkb:Immature BRI2(gene name synonym)|uniprotkb:Transmembrane protein BRI(gene name synonym)	psi-mi:kif5a_rat(display_long)|uniprotkb:Kinesin heavy chain neuron-specific 1(gene name synonym)|uniprotkb:Neuronal kinesin heavy chain(gene name synonym)|uniprotkb:Kif5a(gene name)|psi-mi:Kif5a(display_short)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Martins et al. (2018)	imex:IM-28469|pubmed:29476059	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26440627|imex:IM-28469-5	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSRNOG00000016271(gene)|ensembl:ENSRNOT00000023037(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001540"(amyloid-beta binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0010008"(endosome membrane)|go:"GO:0030660"(Golgi-associated vesicle membrane)|go:"GO:0031301"(integral component of organelle membrane)|go:"GO:0042985"(negative regulation of amyloid precursor protein biosynthetic process)|interpro:IPR007084(BRICHOS)|interpro:IPR040145|mint:Q5XIE8|refseq:NP_001006964.1|rgd:620727	rgd:1303035|refseq:NP_997688.1|mint:Q6QLM7|dip:DIP-46364N|go:"GO:0008574"(plus-end-directed microtubule motor activity)|go:"GO:0016192"(vesicle-mediated transport)|go:"GO:0019894"(kinesin binding)|go:"GO:0021766"(hippocampus development)|go:"GO:0021794"(thalamus development)|go:"GO:0021987"(cerebral cortex development)|go:"GO:0030424"(axon)|go:"GO:0030425"(dendrite)|go:"GO:0030705"(cytoskeleton-dependent intracellular transport)|go:"GO:0032839"(dendrite cytoplasm)|go:"GO:0035253"(ciliary rootlet)|go:"GO:0043005"(neuron projection)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043204"(perikaryon)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0048489"(synaptic vesicle transport)|go:"GO:0048666"(neuron development)|go:"GO:0071361"(cellular response to ethanol)|go:"GO:0090724"(central region of growth cone)|go:"GO:0097110"(scaffold protein binding)|go:"GO:0097440"(apical dendrite)|go:"GO:0098971"(anterograde dendritic transport of neurotransmitter receptor complex)|go:"GO:0099641"(anterograde axonal protein transport)|go:"GO:1904115"(axon cytoplasm)|go:"GO:1904647"(response to rotenone)|go:"GO:1990049"(retrograde neuronal dense core vesicle transport)|go:"GO:1990090"(cellular response to nerve growth factor stimulus)|interpro:IPR001752(Kinesin, motor region)|interpro:IPR027640|interpro:IPR036961|rcsb pdb:2KIN|interpro:IPR027417|rcsb pdb:3KIN|reactome:R-RNO-2132295|reactome:R-RNO-5625970|reactome:R-RNO-6811434|reactome:R-RNO-983189|go:"GO:0000932"(P-body)|go:"GO:0003777"(microtubule motor activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005871"(kinesin complex)|go:"GO:0005874"(microtubule)|go:"GO:0007017"(microtubule-based process)|go:"GO:0007018"(microtubule-based movement)|go:"GO:0007411"(axon guidance)|go:"GO:0008017"(microtubule binding)	-	-	comment:mint|comment:homomint|function:"Microtubule-dependent motor required for slow axonal transport of neurofilament proteins (NFH, NFM and NFL)"	figure legend:st1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10116(rat-hippocampus)|taxid:10116(Rattus norvegicus hippocampal neurons)	-	2020/10/30	2020/10/30	rogid:DtE+ZXAZKdCMvUW5K+jXQ5bH07M10116	rogid:8Rs5XnQSfYtBkTw31UqIBAtb/wY10116	rigid:zzsc1zNhBb5nwIRPeFpYOKgC3M8	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q5XIE8	uniprotkb:Q7TQ16	intact:EBI-15348306|ensembl:ENSRNOP00000023037	intact:EBI-7626900|intact:UNK-5495741|ensembl:ENSRNOP00000065074	psi-mi:itm2b_rat(display_long)|uniprotkb:Itm2b(gene name)|psi-mi:Itm2b(display_short)|uniprotkb:Immature BRI2(gene name synonym)|uniprotkb:Transmembrane protein BRI(gene name synonym)	psi-mi:qcr8_rat(display_long)|uniprotkb:Uqcrq(gene name)|psi-mi:Uqcrq(display_short)|uniprotkb:Complex III subunit 8(gene name synonym)|uniprotkb:Complex III subunit VIII(gene name synonym)|uniprotkb:Low molecular mass ubiquinone-binding protein(gene name synonym)|uniprotkb:Qpc(gene name synonym)|uniprotkb:Ubiquinol-cytochrome c reductase complex 9.5 kDa protein(gene name synonym)|uniprotkb:Ubiquinol-cytochrome c reductase complex ubiquinone-binding protein QP-C(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Martins et al. (2018)	imex:IM-28469|pubmed:29476059	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26440627|imex:IM-28469-5	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSRNOG00000016271(gene)|ensembl:ENSRNOT00000023037(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001540"(amyloid-beta binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0010008"(endosome membrane)|go:"GO:0030660"(Golgi-associated vesicle membrane)|go:"GO:0031301"(integral component of organelle membrane)|go:"GO:0042985"(negative regulation of amyloid precursor protein biosynthetic process)|interpro:IPR007084(BRICHOS)|interpro:IPR040145|mint:Q5XIE8|refseq:NP_001006964.1|rgd:620727	refseq:NP_001020305.1|rgd:1562350|ensembl:ENSRNOG00000048174(gene)|ensembl:ENSRNOT00000073964(transcript)|go:"GO:0005739"(mitochondrion)|go:"GO:0005750"(mitochondrial respiratory chain complex III)|go:"GO:0006122"(mitochondrial electron transport, ubiquinol to cytochrome c)|go:"GO:0021539"(subthalamus development)|go:"GO:0021548"(pons development)|go:"GO:0021680"(cerebellar Purkinje cell layer development)|go:"GO:0021766"(hippocampus development)|go:"GO:0021794"(thalamus development)|go:"GO:0021854"(hypothalamus development)|go:"GO:0021860"(pyramidal neuron development)|go:"GO:0030901"(midbrain development)|go:"GO:1902600"(proton transmembrane transport)|interpro:IPR036642|mint:Q7TQ16|reactome:R-RNO-611105|interpro:IPR004205(UcrQ)|refseq:XP_006246378.1	-	-	comment:mint	figure legend:st1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10116(rat-hippocampus)|taxid:10116(Rattus norvegicus hippocampal neurons)	-	2020/10/30	2020/10/30	rogid:DtE+ZXAZKdCMvUW5K+jXQ5bH07M10116	rogid:3bMevxh5qeqP+F+G2L+pD+rBK6s10116	rigid:zzsc1zNhBb5nwIRPeFpYOKgC3M8	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q5XIE8	uniprotkb:P62744	intact:EBI-15348306|ensembl:ENSRNOP00000023037	intact:EBI-7617461|uniprotkb:P70626|uniprotkb:Q00380|uniprotkb:P97626|intact:MINT-2514729|ensembl:ENSRNOP00000021310	psi-mi:itm2b_rat(display_long)|uniprotkb:Itm2b(gene name)|psi-mi:Itm2b(display_short)|uniprotkb:Immature BRI2(gene name synonym)|uniprotkb:Transmembrane protein BRI(gene name synonym)	psi-mi:ap2s1_rat(display_long)|uniprotkb:Clathrin assembly protein 2 sigma small chain(gene name synonym)|uniprotkb:Ap2s1(gene name)|psi-mi:Ap2s1(display_short)|uniprotkb:Ap17(gene name synonym)|uniprotkb:Claps2(gene name synonym)|uniprotkb:Adaptor protein complex AP-2 subunit sigma(gene name synonym)|uniprotkb:Sigma2-adaptin(gene name synonym)|uniprotkb:Sigma-adaptin 3b(gene name synonym)|uniprotkb:Plasma membrane adaptor AP-2 17 kDa protein(gene name synonym)|uniprotkb:Clathrin coat assembly protein AP17(gene name synonym)|uniprotkb:Clathrin coat-associated protein AP17(gene name synonym)|uniprotkb:Adaptor-related protein complex 2 subunit sigma(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Martins et al. (2018)	imex:IM-28469|pubmed:29476059	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26440627|imex:IM-28469-5	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSRNOG00000016271(gene)|ensembl:ENSRNOT00000023037(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001540"(amyloid-beta binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0010008"(endosome membrane)|go:"GO:0030660"(Golgi-associated vesicle membrane)|go:"GO:0031301"(integral component of organelle membrane)|go:"GO:0042985"(negative regulation of amyloid precursor protein biosynthetic process)|interpro:IPR007084(BRICHOS)|interpro:IPR040145|mint:Q5XIE8|refseq:NP_001006964.1|rgd:620727	rgd:620188|refseq:NP_075241.2|ensembl:ENSRNOG00000015865(gene)|ensembl:ENSRNOT00000021310(transcript)|go:"GO:0005886"(plasma membrane)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0016192"(vesicle-mediated transport)|go:"GO:0030122"(AP-2 adaptor complex)|go:"GO:0035615"(clathrin adaptor activity)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0072583"(clathrin-dependent endocytosis)|interpro:IPR000804(Clathrin adaptor, sigma subunit/coatomer, zeta subunit)|interpro:IPR011012(Longin-like)|interpro:IPR016635(Adaptor protein complex, sigma subunit)|interpro:IPR022775|interpro:IPR027156|rcsb pdb:4NEE|rcsb pdb:6OWO|rcsb pdb:6OWT|rcsb pdb:6OXL|reactome:R-RNO-177504|reactome:R-RNO-2132295|reactome:R-RNO-416993|reactome:R-RNO-437239|reactome:R-RNO-5099900|reactome:R-RNO-5140745|reactome:R-RNO-8856825|reactome:R-RNO-8856828|reactome:R-RNO-8866427|reactome:R-RNO-8964038|mint:P62744	-	-	function:Component of the adaptor complexes which link clathrin to receptors in coated vesicles. Clathrin-associated protein complexes are believed to interact with the cytoplasmic tails of membrane proteins, leading to their selection and concentration. AP2S1/AP17 is a subunit of the plasma membrane adaptor. The complex binds polyphosphoinositides|comment:mint	figure legend:st1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10116(rat-hippocampus)|taxid:10116(Rattus norvegicus hippocampal neurons)	-	2020/10/30	2020/10/30	rogid:DtE+ZXAZKdCMvUW5K+jXQ5bH07M10116	rogid:AJxHeeoCpwPxjsRcAQkiAGaC9k010116	rigid:zzsc1zNhBb5nwIRPeFpYOKgC3M8	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q5XIE8	uniprotkb:P62944	intact:EBI-15348306|ensembl:ENSRNOP00000023037	intact:EBI-7048246|ensembl:ENSRNOP00000072290|uniprotkb:P21851|intact:MINT-122517	psi-mi:itm2b_rat(display_long)|uniprotkb:Itm2b(gene name)|psi-mi:Itm2b(display_short)|uniprotkb:Immature BRI2(gene name synonym)|uniprotkb:Transmembrane protein BRI(gene name synonym)	psi-mi:ap2b1_rat(display_long)|uniprotkb:Ap2b1(gene name)|psi-mi:Ap2b1(display_short)|uniprotkb:Clapb1(gene name synonym)|uniprotkb:Beta-adaptin(gene name synonym)|uniprotkb:Plasma membrane adaptor HA2/AP2 adaptin beta subunit(gene name synonym)|uniprotkb:Clathrin assembly protein complex 2 beta large chain(gene name synonym)|uniprotkb:AP105B(gene name synonym)|uniprotkb:Adaptor protein complex AP-2 subunit beta(gene name synonym)|uniprotkb:Beta-2-adaptin(gene name synonym)|uniprotkb:Adaptor-related protein complex 2 subunit beta(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Martins et al. (2018)	imex:IM-28469|pubmed:29476059	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26440627|imex:IM-28469-5	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSRNOG00000016271(gene)|ensembl:ENSRNOT00000023037(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001540"(amyloid-beta binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0010008"(endosome membrane)|go:"GO:0030660"(Golgi-associated vesicle membrane)|go:"GO:0031301"(integral component of organelle membrane)|go:"GO:0042985"(negative regulation of amyloid precursor protein biosynthetic process)|interpro:IPR007084(BRICHOS)|interpro:IPR040145|mint:Q5XIE8|refseq:NP_001006964.1|rgd:620727	refseq:XP_008766157.1|refseq:XP_008766158.1|refseq:XP_008766159.1|refseq:XP_008766160.1|refseq:XP_008766161.1|ensembl:ENSRNOG00000061543(gene)|ensembl:ENSRNOT00000085799(transcript)|go:"GO:0001822"(kidney development)|go:"GO:0003279"(cardiac septum development)|go:"GO:0003281"(ventricular septum development)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0007507"(heart development)|go:"GO:0016192"(vesicle-mediated transport)|go:"GO:0030118"(clathrin coat)|go:"GO:0030119"(AP-type membrane coat adaptor complex)|go:"GO:0030122"(AP-2 adaptor complex)|go:"GO:0030131"(clathrin adaptor complex)|go:"GO:0030276"(clathrin binding)|go:"GO:0035904"(aorta development)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045807"(positive regulation of endocytosis)|go:"GO:0048268"(clathrin coat assembly)|go:"GO:0060976"(coronary vasculature development)|go:"GO:0098794"(postsynapse)|go:"GO:0098884"(postsynaptic neurotransmitter receptor internalization)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099590"(neurotransmitter receptor internalization)|go:"GO:1901215"(negative regulation of neuron death)|go:"GO:1905477"(positive regulation of protein localization to membrane)|interpro:IPR000225(Armadillo)|interpro:IPR002553(Clathrin/coatomer adaptor, adaptin-like, N-terminal)|interpro:IPR008152(Clathrin adaptor, alpha/beta/gamma-adaptin, appendage, Ig-like subdomain)|interpro:IPR009028(Clathrin/coatomer adaptor, adaptin-like, appendage, C-terminal subdomain)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR012295(Beta2-adaptin/TATA-box binding, C-terminal)|interpro:IPR013037(Clathrin adaptor, beta-adaptin, appendage, Ig-like subdomain)|interpro:IPR013041(Clathrin/coatomer adaptor, adaptin-like, appendage, Ig-like subdomain)|interpro:IPR015151(Clathrin adaptor, beta-adaptin, appendage, C-terminal subdomain)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR016342(Adaptor protein complex, beta subunit)|interpro:IPR026739|mint:P62944|rcsb pdb:3H1Z|rcsb pdb:3HS9|rcsb pdb:6OWT|reactome:R-RNO-177504|reactome:R-RNO-2132295|reactome:R-RNO-416993|reactome:R-RNO-437239|reactome:R-RNO-5099900|reactome:R-RNO-5140745|go:"GO:0072583"(clathrin-dependent endocytosis)|reactome:R-RNO-8856825|reactome:R-RNO-8856828|reactome:R-RNO-8866427|reactome:R-RNO-8964038|refseq:XP_017452462.1|refseq:NP_542150.1|rgd:71048|dip:DIP-40944N	-	-	function:Component of the adaptor complexes which link clathrin to receptors in coated vesicles. Clathrin-associated protein complexes are believed to interact with the cytoplasmic tails of membrane proteins, leading to their selection and concentration. AP2B1 is a subunit of the plasma membrane adaptor. The complex binds polyphosphoinositides|comment:mint	figure legend:st1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10116(rat-hippocampus)|taxid:10116(Rattus norvegicus hippocampal neurons)	-	2020/10/30	2020/10/30	rogid:DtE+ZXAZKdCMvUW5K+jXQ5bH07M10116	rogid:Q5oFhdE1hcmqu7xLG3MteCu0Zcg10116	rigid:zzsc1zNhBb5nwIRPeFpYOKgC3M8	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q5XIE8	uniprotkb:O35458	intact:EBI-15348306|ensembl:ENSRNOP00000023037	intact:EBI-7281062|intact:UNK-5362087|ensembl:ENSRNOP00000020720	psi-mi:itm2b_rat(display_long)|uniprotkb:Itm2b(gene name)|psi-mi:Itm2b(display_short)|uniprotkb:Immature BRI2(gene name synonym)|uniprotkb:Transmembrane protein BRI(gene name synonym)	psi-mi:viaat_rat(display_long)|uniprotkb:Slc32a1(gene name)|psi-mi:Slc32a1(display_short)|uniprotkb:Vgat(gene name synonym)|uniprotkb:Viaat(gene name synonym)|uniprotkb:GABA and glycine transporter(gene name synonym)|uniprotkb:Vesicular GABA transporter(gene name synonym)|uniprotkb:Solute carrier family 32 member 1(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Martins et al. (2018)	imex:IM-28469|pubmed:29476059	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26440627|imex:IM-28469-5	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSRNOG00000016271(gene)|ensembl:ENSRNOT00000023037(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001540"(amyloid-beta binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0010008"(endosome membrane)|go:"GO:0030660"(Golgi-associated vesicle membrane)|go:"GO:0031301"(integral component of organelle membrane)|go:"GO:0042985"(negative regulation of amyloid precursor protein biosynthetic process)|interpro:IPR007084(BRICHOS)|interpro:IPR040145|mint:Q5XIE8|refseq:NP_001006964.1|rgd:620727	refseq:XP_006235503.1|refseq:NP_113970.1|rgd:621402|ensembl:ENSRNOG00000015393(gene)|ensembl:ENSRNOT00000020720(transcript)|go:"GO:0005886"(plasma membrane)|go:"GO:0006836"(neurotransmitter transport)|go:"GO:0007568"(aging)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0015187"(glycine transmembrane transporter activity)|go:"GO:0015495"("gamma-aminobutyric acid:proton symporter activity")|go:"GO:0015812"(gamma-aminobutyric acid transport)|go:"GO:0015816"(glycine transport)|go:"GO:0016021"(integral component of membrane)|go:"GO:0021766"(hippocampus development)|go:"GO:0030285"(integral component of synaptic vesicle membrane)|go:"GO:0030425"(dendrite)|go:"GO:0043005"(neuron projection)|go:"GO:0043229"(intracellular organelle)|go:"GO:0044292"(dendrite terminus)|go:"GO:0044306"(neuron projection terminus)|go:"GO:0044316"(cone cell pedicle)|go:"GO:0045202"(synapse)|go:"GO:0048786"(presynaptic active zone)|go:"GO:0051286"(cell tip)|go:"GO:0060077"(inhibitory synapse)|go:"GO:0098700"(neurotransmitter loading into synaptic vesicle)|go:"GO:0098982"(GABA-ergic synapse)|interpro:IPR013057(Amino acid transporter, transmembrane)|mint:O35458|reactome:R-RNO-425393|reactome:R-RNO-888590	-	-	function:Involved in the uptake of GABA and glycine into the synaptic vesicles|comment:mint	figure legend:st1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10116(rat-hippocampus)|taxid:10116(Rattus norvegicus hippocampal neurons)	-	2020/10/30	2020/10/30	rogid:DtE+ZXAZKdCMvUW5K+jXQ5bH07M10116	rogid:yejLVaYBDG3n2gt6XV8lN868NYk10116	rigid:zzsc1zNhBb5nwIRPeFpYOKgC3M8	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q5XIE8	uniprotkb:Q62634	intact:EBI-15348306|ensembl:ENSRNOP00000023037	intact:EBI-7280977|intact:MINT-4784487|uniprotkb:A9LRT0|ensembl:ENSRNOP00000028064	psi-mi:itm2b_rat(display_long)|uniprotkb:Itm2b(gene name)|psi-mi:Itm2b(display_short)|uniprotkb:Immature BRI2(gene name synonym)|uniprotkb:Transmembrane protein BRI(gene name synonym)	psi-mi:vglu1_rat(display_long)|uniprotkb:Slc17a7(gene name)|psi-mi:Slc17a7(display_short)|uniprotkb:Bnpi(gene name synonym)|uniprotkb:Vglut1(gene name synonym)|uniprotkb:Solute carrier family 17 member 7(gene name synonym)|uniprotkb:"Brain-specific Na(+)-dependent inorganic phosphate cotransporter"(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Martins et al. (2018)	imex:IM-28469|pubmed:29476059	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26440627|imex:IM-28469-5	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSRNOG00000016271(gene)|ensembl:ENSRNOT00000023037(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001540"(amyloid-beta binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0010008"(endosome membrane)|go:"GO:0030660"(Golgi-associated vesicle membrane)|go:"GO:0031301"(integral component of organelle membrane)|go:"GO:0042985"(negative regulation of amyloid precursor protein biosynthetic process)|interpro:IPR007084(BRICHOS)|interpro:IPR040145|mint:Q5XIE8|refseq:NP_001006964.1|rgd:620727	rgd:620101|refseq:NP_446311.1|ensembl:ENSRNOG00000020650(gene)|ensembl:ENSRNOT00000028064(transcript)|go:"GO:0003407"(neural retina development)|go:"GO:0005313"(L-glutamate transmembrane transporter activity)|go:"GO:0005315"(inorganic phosphate transmembrane transporter activity)|go:"GO:0005326"(neurotransmitter transmembrane transporter activity)|go:"GO:0005436"("sodium:phosphate symporter activity")|go:"GO:0006817"(phosphate ion transport)|go:"GO:0007268"(chemical synaptic transmission)|go:"GO:0007420"(brain development)|go:"GO:0007616"(long-term memory)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0008068"(extracellularly glutamate-gated chloride channel activity)|go:"GO:0015319"("sodium:inorganic phosphate symporter activity")|go:"GO:0016021"(integral component of membrane)|go:"GO:0022857"(transmembrane transporter activity)|go:"GO:0030285"(integral component of synaptic vesicle membrane)|go:"GO:0030672"(synaptic vesicle membrane)|go:"GO:0035249"(synaptic transmission, glutamatergic)|go:"GO:0042137"(sequestering of neurotransmitter)|go:"GO:0043229"(intracellular organelle)|go:"GO:0044300"(cerebellar mossy fiber)|go:"GO:0045202"(synapse)|go:"GO:0048786"(presynaptic active zone)|go:"GO:0050803"(regulation of synapse structure or activity)|go:"GO:0051938"(L-glutamate import)|go:"GO:0060076"(excitatory synapse)|go:"GO:0060079"(excitatory postsynaptic potential)|go:"GO:0097401"(synaptic vesicle lumen acidification)|go:"GO:0098700"(neurotransmitter loading into synaptic vesicle)|go:"GO:0098794"(postsynapse)|go:"GO:1900242"(regulation of synaptic vesicle endocytosis)|interpro:IPR011701(Major facilitator superfamily MFS-1)|interpro:IPR020846|interpro:IPR036259|mint:Q62634|reactome:R-RNO-210500|reactome:R-RNO-428643|go:"GO:0006820"(anion transport)	-	-	comment:mint	figure legend:st1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10116(rat-hippocampus)|taxid:10116(Rattus norvegicus hippocampal neurons)	-	2020/10/30	2020/10/30	rogid:DtE+ZXAZKdCMvUW5K+jXQ5bH07M10116	rogid:UbaEJLA0CIT48OoJn8wT3wgvP1s10116	rigid:zzsc1zNhBb5nwIRPeFpYOKgC3M8	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q5XIE8	uniprotkb:D4AB66	intact:EBI-15348306|ensembl:ENSRNOP00000023037	intact:EBI-8514708|intact:MINT-8092238|ensembl:ENSRNOP00000005881	psi-mi:itm2b_rat(display_long)|uniprotkb:Itm2b(gene name)|psi-mi:Itm2b(display_short)|uniprotkb:Immature BRI2(gene name synonym)|uniprotkb:Transmembrane protein BRI(gene name synonym)	psi-mi:ston2_rat(display_long)|uniprotkb:Ston2(gene name)|psi-mi:Ston2(display_short)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Martins et al. (2018)	imex:IM-28469|pubmed:29476059	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26440627|imex:IM-28469-5	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSRNOG00000016271(gene)|ensembl:ENSRNOT00000023037(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001540"(amyloid-beta binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0010008"(endosome membrane)|go:"GO:0030660"(Golgi-associated vesicle membrane)|go:"GO:0031301"(integral component of organelle membrane)|go:"GO:0042985"(negative regulation of amyloid precursor protein biosynthetic process)|interpro:IPR007084(BRICHOS)|interpro:IPR040145|mint:Q5XIE8|refseq:NP_001006964.1|rgd:620727	rgd:1311502|refseq:NP_001129346.1|refseq:XP_006240468.1|refseq:XP_006240469.1|ensembl:ENSRNOG00000004458(gene)|ensembl:ENSRNOT00000005881(transcript)|go:"GO:0002244"(hematopoietic progenitor cell differentiation)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0016020"(membrane)|go:"GO:0016192"(vesicle-mediated transport)|go:"GO:0030100"(regulation of endocytosis)|go:"GO:0030136"(clathrin-coated vesicle)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0035615"(clathrin adaptor activity)|go:"GO:0043005"(neuron projection)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0048488"(synaptic vesicle endocytosis)|go:"GO:0098793"(presynapse)|interpro:IPR012320(Stonin homology)|interpro:IPR017110(Stonin)|interpro:IPR022699|interpro:IPR028565|interpro:IPR031228|interpro:IPR036168|mint:D4AB66|reactome:R-RNO-8856825|reactome:R-RNO-8856828	-	-	comment:mint	figure legend:st1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10116(rat-hippocampus)|taxid:10116(Rattus norvegicus hippocampal neurons)	-	2020/10/30	2020/10/30	rogid:DtE+ZXAZKdCMvUW5K+jXQ5bH07M10116	rogid:Ly8uUc9VzPOWrOk4jRtwrhzOHvQ10116	rigid:zzsc1zNhBb5nwIRPeFpYOKgC3M8	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q5XIE8	uniprotkb:P97874	intact:EBI-15348306|ensembl:ENSRNOP00000023037	intact:EBI-6947879|intact:MINT-3289568	psi-mi:itm2b_rat(display_long)|uniprotkb:Itm2b(gene name)|psi-mi:Itm2b(display_short)|uniprotkb:Immature BRI2(gene name synonym)|uniprotkb:Transmembrane protein BRI(gene name synonym)	psi-mi:gak_rat(display_long)|uniprotkb:Gak(gene name)|psi-mi:Gak(display_short)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Martins et al. (2018)	imex:IM-28469|pubmed:29476059	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26440627|imex:IM-28469-5	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSRNOG00000016271(gene)|ensembl:ENSRNOT00000023037(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001540"(amyloid-beta binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0010008"(endosome membrane)|go:"GO:0030660"(Golgi-associated vesicle membrane)|go:"GO:0031301"(integral component of organelle membrane)|go:"GO:0042985"(negative regulation of amyloid precursor protein biosynthetic process)|interpro:IPR007084(BRICHOS)|interpro:IPR040145|mint:Q5XIE8|refseq:NP_001006964.1|rgd:620727	go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0005925"(focal adhesion)|go:"GO:0006898"(receptor-mediated endocytosis)|go:"GO:0007029"(endoplasmic reticulum organization)|go:"GO:0007030"(Golgi organization)|go:"GO:0007049"(cell cycle)|go:"GO:0009913"(epidermal cell differentiation)|go:"GO:0010977"(negative regulation of neuron projection development)|go:"GO:0030276"(clathrin binding)|go:"GO:0030332"(cyclin binding)|go:"GO:0031982"(vesicle)|go:"GO:0034067"(protein localization to Golgi apparatus)|go:"GO:0035622"(intrahepatic bile duct development)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0048468"(cell development)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0048853"(forebrain morphogenesis)|go:"GO:0061436"(establishment of skin barrier)|go:"GO:0072318"(clathrin coat disassembly)|go:"GO:0072583"(clathrin-dependent endocytosis)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0090160"(Golgi to lysosome transport)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:1905224"(clathrin-coated pit assembly)|go:"GO:2000179"(positive regulation of neural precursor cell proliferation)|reactome:R-RNO-432722|reactome:R-RNO-8856828|interpro:IPR000719(Protein kinase, core)|interpro:IPR001623(Heat shock protein DnaJ, N-terminal)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR035892|refseq:NP_112292.1|interpro:IPR014020(C2 tensin-type)|rgd:621589|interpro:IPR011009(Protein kinase-like)|interpro:IPR029021|interpro:IPR029023|mint:P97874|interpro:IPR036869	-	-	comment:mint|function:Associates with cyclin G and CDK5. Seems to act as an auxilin homolog that is involved in the uncoating of clathrin-coated vesicles by Hsc70 in non-neuronal cells. Expression oscillates slightly during the cell cycle, peaking at G1	figure legend:st1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10116(rat-hippocampus)|taxid:10116(Rattus norvegicus hippocampal neurons)	-	2020/10/30	2020/10/30	rogid:DtE+ZXAZKdCMvUW5K+jXQ5bH07M10116	rogid:Y8JA/CKcFHMi5e0baHUVN0RNYVM10116	rigid:zzsc1zNhBb5nwIRPeFpYOKgC3M8	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q5XIE8	uniprotkb:P69682	intact:EBI-15348306|ensembl:ENSRNOP00000023037	intact:EBI-7592718|intact:MINT-5260811|uniprotkb:Q4QR67|ensembl:ENSRNOP00000013272	psi-mi:itm2b_rat(display_long)|uniprotkb:Itm2b(gene name)|psi-mi:Itm2b(display_short)|uniprotkb:Immature BRI2(gene name synonym)|uniprotkb:Transmembrane protein BRI(gene name synonym)	psi-mi:necp1_rat(display_long)|uniprotkb:Necap1(gene name)|psi-mi:Necap1(display_short)|uniprotkb:NECAP endocytosis-associated protein 1(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Martins et al. (2018)	imex:IM-28469|pubmed:29476059	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26440627|imex:IM-28469-5	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSRNOG00000016271(gene)|ensembl:ENSRNOT00000023037(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001540"(amyloid-beta binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0010008"(endosome membrane)|go:"GO:0030660"(Golgi-associated vesicle membrane)|go:"GO:0031301"(integral component of organelle membrane)|go:"GO:0042985"(negative regulation of amyloid precursor protein biosynthetic process)|interpro:IPR007084(BRICHOS)|interpro:IPR040145|mint:Q5XIE8|refseq:NP_001006964.1|rgd:620727	refseq:NP_001025090.1|rgd:1306053|ensembl:ENSRNOG00000009236(gene)|ensembl:ENSRNOT00000013272(transcript)|go:"GO:0005905"(clathrin-coated pit)|go:"GO:0006897"(endocytosis)|go:"GO:0015031"(protein transport)|go:"GO:0016192"(vesicle-mediated transport)|go:"GO:0030125"(clathrin vesicle coat)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR012466(Adaptin ear-binding coat-associated protein 1 NECAP-1)|mint:P69682|reactome:R-RNO-432722|reactome:R-RNO-8856825|reactome:R-RNO-8856828|dip:DIP-44064N	-	-	comment:mint|function:Involved in endocytosis	figure legend:st1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10116(rat-hippocampus)|taxid:10116(Rattus norvegicus hippocampal neurons)	-	2020/10/30	2020/10/30	rogid:DtE+ZXAZKdCMvUW5K+jXQ5bH07M10116	rogid:KwuJp3lG7BL4q4Fzy7YtThmdCso10116	rigid:zzsc1zNhBb5nwIRPeFpYOKgC3M8	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q5XIE8	uniprotkb:P59215	intact:EBI-15348306|ensembl:ENSRNOP00000023037	intact:EBI-8071125|intact:MINT-5028451|uniprotkb:P04900|intact:MINT-6380317|uniprotkb:P30033|ensembl:ENSRNOP00000026373	psi-mi:itm2b_rat(display_long)|uniprotkb:Itm2b(gene name)|psi-mi:Itm2b(display_short)|uniprotkb:Immature BRI2(gene name synonym)|uniprotkb:Transmembrane protein BRI(gene name synonym)	psi-mi:gnao_rat(display_long)|uniprotkb:Gnao1(gene name)|psi-mi:Gnao1(display_short)|uniprotkb:Gna0(gene name synonym)|uniprotkb:Gnao(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Martins et al. (2018)	imex:IM-28469|pubmed:29476059	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26440627|imex:IM-28469-5	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSRNOG00000016271(gene)|ensembl:ENSRNOT00000023037(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001540"(amyloid-beta binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0010008"(endosome membrane)|go:"GO:0030660"(Golgi-associated vesicle membrane)|go:"GO:0031301"(integral component of organelle membrane)|go:"GO:0042985"(negative regulation of amyloid precursor protein biosynthetic process)|interpro:IPR007084(BRICHOS)|interpro:IPR040145|mint:Q5XIE8|refseq:NP_001006964.1|rgd:620727	rgd:628732|refseq:NP_059023.1|dip:DIP-59090N|ensembl:ENSRNOG00000019482(gene)|ensembl:ENSRNOT00000026373(transcript)|go:"GO:0001664"(G protein-coupled receptor binding)|go:"GO:0003924"(GTPase activity)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005525"(GTP binding)|go:"GO:0005834"(heterotrimeric G-protein complex)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0007188"(adenylate cyclase-modulating G protein-coupled receptor signaling pathway)|go:"GO:0007212"(dopamine receptor signaling pathway)|go:"GO:0007568"(aging)|go:"GO:0007626"(locomotory behavior)|go:"GO:0008016"(regulation of heart contraction)|go:"GO:0009987"(cellular process)|go:"GO:0014070"(response to organic cyclic compound)|go:"GO:0016020"(membrane)|go:"GO:0019003"(GDP binding)|go:"GO:0030425"(dendrite)|go:"GO:0030900"(forebrain development)|go:"GO:0031175"(neuron projection development)|go:"GO:0031683"(G-protein beta/gamma-subunit complex binding)|go:"GO:0031821"(G protein-coupled serotonin receptor binding)|go:"GO:0031852"(mu-type opioid receptor binding)|go:"GO:0032794"(GTPase activating protein binding)|go:"GO:0034097"(response to cytokine)|go:"GO:0042475"(odontogenesis of dentin-containing tooth)|go:"GO:0042493"|go:"GO:0042542"(response to hydrogen peroxide)|go:"GO:0043005"(neuron projection)|go:"GO:0043209"(myelin sheath)|go:"GO:0043278"(response to morphine)|go:"GO:0043547"(positive regulation of GTPase activity)|go:"GO:0044297"(cell body)|go:"GO:0046872"(metal ion binding)|go:"GO:0051430"(corticotropin-releasing hormone receptor 1 binding)|go:"GO:0051926"(negative regulation of calcium ion transport)|interpro:IPR001019("Guanine nucleotide binding protein (G-protein), alpha subunit")|interpro:IPR001408(G-protein alpha subunit, group I)|interpro:IPR011025(G protein alpha subunit, helical insertion)|interpro:IPR027417|mint:P59215|reactome:R-RNO-4086398|go:"GO:0010243"(response to organonitrogen compound)	-	-	comment:mint|function:"Guanine nucleotide-binding proteins (G proteins) are involved as modulators or transducers in various transmembrane signaling systems. The G(o) protein function is not clear"|comment:homomint	figure legend:st1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10116(rat-hippocampus)|taxid:10116(Rattus norvegicus hippocampal neurons)	-	2020/10/30	2020/10/30	rogid:DtE+ZXAZKdCMvUW5K+jXQ5bH07M10116	rogid:LuKGAVyaFxWTp6ctQzokHhwyo3410116	rigid:zzsc1zNhBb5nwIRPeFpYOKgC3M8	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q5XIE8	uniprotkb:P06687	intact:EBI-15348306|ensembl:ENSRNOP00000023037	intact:EBI-7617807|intact:MINT-7138201|uniprotkb:Q9Z1G6|uniprotkb:Q16732|ensembl:ENSRNOP00000027497	psi-mi:itm2b_rat(display_long)|uniprotkb:Itm2b(gene name)|psi-mi:Itm2b(display_short)|uniprotkb:Immature BRI2(gene name synonym)|uniprotkb:Transmembrane protein BRI(gene name synonym)	psi-mi:at1a3_rat(display_long)|uniprotkb:Atp1a3(gene name)|psi-mi:Atp1a3(display_short)|uniprotkb:"Na(+)/K(+) ATPase alpha(III) subunit"(gene name synonym)|uniprotkb:Sodium pump subunit alpha-3(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Martins et al. (2018)	imex:IM-28469|pubmed:29476059	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26440627|imex:IM-28469-5	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSRNOG00000016271(gene)|ensembl:ENSRNOT00000023037(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001540"(amyloid-beta binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0010008"(endosome membrane)|go:"GO:0030660"(Golgi-associated vesicle membrane)|go:"GO:0031301"(integral component of organelle membrane)|go:"GO:0042985"(negative regulation of amyloid precursor protein biosynthetic process)|interpro:IPR007084(BRICHOS)|interpro:IPR040145|mint:Q5XIE8|refseq:NP_001006964.1|rgd:620727	rgd:2169|refseq:NP_036638.1|ensembl:ENSRNOG00000020263(gene)|ensembl:ENSRNOT00000027497(transcript)|go:"GO:0001540"(amyloid-beta binding)|go:"GO:0001917"(photoreceptor inner segment)|go:"GO:0005391"("P-type sodium:potassium-exchanging transporter activity")|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005890"("sodium:potassium-exchanging ATPase complex")|go:"GO:0006813"(potassium ion transport)|go:"GO:0006814"(sodium ion transport)|go:"GO:0006883"(cellular sodium ion homeostasis)|go:"GO:0007613"(memory)|go:"GO:0008344"(adult locomotory behavior)|go:"GO:0008542"(visual learning)|go:"GO:0016020"(membrane)|go:"GO:0021987"(cerebral cortex development)|go:"GO:0030007"(cellular potassium ion homeostasis)|go:"GO:0030424"(axon)|go:"GO:0031090"(organelle membrane)|go:"GO:0031748"(D1 dopamine receptor binding)|go:"GO:0035235"(ionotropic glutamate receptor signaling pathway)|go:"GO:0036376"(sodium ion export across plasma membrane)|go:"GO:0042383"(sarcolemma)|go:"GO:0042493"|go:"GO:0043025"(neuronal cell body)|go:"GO:0043209"(myelin sheath)|go:"GO:0043395"(heparan sulfate proteoglycan binding)|go:"GO:0044305"(calyx of Held)|go:"GO:0044326"(dendritic spine neck)|go:"GO:0044327"(dendritic spine head)|go:"GO:0045202"(synapse)|go:"GO:0046872"(metal ion binding)|go:"GO:0051087"(chaperone binding)|go:"GO:0060048"(cardiac muscle contraction)|go:"GO:0071300"(cellular response to retinoic acid)|go:"GO:0086036"(regulation of cardiac muscle cell membrane potential)|go:"GO:0086037"("P-type sodium:potassium-exchanging transporter activity involved in regulation of cardiac muscle cell membrane potential")|go:"GO:0097067"(cellular response to thyroid hormone stimulus)|go:"GO:0098794"(postsynapse)|go:"GO:0098984"(neuron to neuron synapse)|go:"GO:0099056"(integral component of presynaptic membrane)|go:"GO:0099520"(ion antiporter activity involved in regulation of presynaptic membrane potential)|go:"GO:1902600"(proton transmembrane transport)|go:"GO:1904646"(cellular response to amyloid-beta)|go:"GO:1990535"(neuron projection maintenance)|go:"GO:1990573"(potassium ion import across plasma membrane)|interpro:IPR001757(ATPase, P-type, K/Mg/Cd/Cu/Zn/Na/Ca/Na/H-transporter)|interpro:IPR004014(ATPase, P-type cation-transporter, N-terminal)|interpro:IPR005775(ATPase, P-type cation exchange, alpha subunit, eukaryotic)|interpro:IPR006068(ATPase, P-type cation-transporter, C-terminal)|interpro:IPR008250(E1-E2 ATPase-associated region)|interpro:IPR018303|interpro:IPR023214|interpro:IPR023298|interpro:IPR023299|interpro:IPR036412|interpro:IPR044492|mint:P06687|reactome:R-RNO-5578775|reactome:R-RNO-936837|go:"GO:0005886"(plasma membrane)	-	-	comment:mint	figure legend:st1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10116(rat-hippocampus)|taxid:10116(Rattus norvegicus hippocampal neurons)	-	2020/10/30	2020/10/30	rogid:DtE+ZXAZKdCMvUW5K+jXQ5bH07M10116	rogid:1sz4qkpfVGTvDfvmBVIE3wsH2Rs10116	rigid:zzsc1zNhBb5nwIRPeFpYOKgC3M8	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q5XIE8	uniprotkb:Q62717	intact:EBI-15348306|ensembl:ENSRNOP00000023037	intact:EBI-15804323	psi-mi:itm2b_rat(display_long)|uniprotkb:Itm2b(gene name)|psi-mi:Itm2b(display_short)|uniprotkb:Immature BRI2(gene name synonym)|uniprotkb:Transmembrane protein BRI(gene name synonym)	psi-mi:caps1_rat(display_long)|uniprotkb:Cadps(gene name)|psi-mi:Cadps(display_short)|uniprotkb:Caps(gene name synonym)|uniprotkb:Caps1(gene name synonym)|uniprotkb:Calcium-dependent activator protein for secretion 1(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Martins et al. (2018)	imex:IM-28469|pubmed:29476059	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26440627|imex:IM-28469-5	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSRNOG00000016271(gene)|ensembl:ENSRNOT00000023037(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001540"(amyloid-beta binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0010008"(endosome membrane)|go:"GO:0030660"(Golgi-associated vesicle membrane)|go:"GO:0031301"(integral component of organelle membrane)|go:"GO:0042985"(negative regulation of amyloid precursor protein biosynthetic process)|interpro:IPR007084(BRICHOS)|interpro:IPR040145|mint:Q5XIE8|refseq:NP_001006964.1|rgd:620727	go:"GO:0005509"(calcium ion binding)|go:"GO:0005546"(phosphatidylinositol-4,5-bisphosphate binding)|go:"GO:0006887"(exocytosis)|go:"GO:0015031"(protein transport)|go:"GO:0016050"(vesicle organization)|go:"GO:0016082"(synaptic vesicle priming)|go:"GO:0019901"(protein kinase binding)|go:"GO:0031045"(dense core granule)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0045055"(regulated exocytosis)|go:"GO:0045921"(positive regulation of exocytosis)|go:"GO:0045956"(positive regulation of calcium ion-dependent exocytosis)|go:"GO:0050432"(catecholamine secretion)|go:"GO:0098674"(extrinsic component of neuronal dense core vesicle membrane)|go:"GO:0098793"(presynapse)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099525"(presynaptic dense core vesicle exocytosis)|interpro:IPR000008(C2 calcium-dependent membrane targeting)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR010439(Protein of unknown function DUF1041)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR014770(Munc13 homology 1)|interpro:IPR033227|rcsb pdb:6A68|mint:Q62717|refseq:NP_037351.1|rgd:708573|dip:DIP-58640N	-	-	-	figure legend:st1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10116(rat-hippocampus)|taxid:10116(Rattus norvegicus hippocampal neurons)	-	2020/10/30	2020/10/30	rogid:DtE+ZXAZKdCMvUW5K+jXQ5bH07M10116	rogid:fq1A0iMLllu/HOzqUetSoEbXzFg10116	rigid:zzsc1zNhBb5nwIRPeFpYOKgC3M8	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q5XIE8	uniprotkb:Q01205	intact:EBI-15348306|ensembl:ENSRNOP00000023037	intact:EBI-918128|uniprotkb:Q5XI35	psi-mi:itm2b_rat(display_long)|uniprotkb:Itm2b(gene name)|psi-mi:Itm2b(display_short)|uniprotkb:Immature BRI2(gene name synonym)|uniprotkb:Transmembrane protein BRI(gene name synonym)	psi-mi:odo2_rat(display_long)|uniprotkb:Dihydrolipoamide succinyltransferase component of 2-oxoglutarate dehydrogenase complex(gene name synonym)|uniprotkb:E2K(gene name synonym)|uniprotkb:Dlst(gene name)|psi-mi:Dlst(display_short)|uniprotkb:2-oxoglutarate dehydrogenase complex component E2(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Martins et al. (2018)	imex:IM-28469|pubmed:29476059	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26440627|imex:IM-28469-5	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSRNOG00000016271(gene)|ensembl:ENSRNOT00000023037(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001540"(amyloid-beta binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0010008"(endosome membrane)|go:"GO:0030660"(Golgi-associated vesicle membrane)|go:"GO:0031301"(integral component of organelle membrane)|go:"GO:0042985"(negative regulation of amyloid precursor protein biosynthetic process)|interpro:IPR007084(BRICHOS)|interpro:IPR040145|mint:Q5XIE8|refseq:NP_001006964.1|rgd:620727	mint:Q01205|rgd:1359615|refseq:NP_001006982.2|interpro:IPR003016(2-oxo acid dehydrogenase, lipoyl-binding site)|interpro:IPR001078(Catalytic domain of components of various dehydrogenase complexes)|interpro:IPR000089(Biotin/lipoyl attachment)|interpro:IPR011053(Single hybrid motif)|interpro:IPR006255(Dihydrolipoamide succinyltransferase)|interpro:IPR023213|go:"GO:0004149"(dihydrolipoyllysine-residue succinyltransferase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005739"(mitochondrion)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0005886"(plasma membrane)|go:"GO:0006099"(tricarboxylic acid cycle)|go:"GO:0006103"(2-oxoglutarate metabolic process)|go:"GO:0006104"(succinyl-CoA metabolic process)|go:"GO:0006734"(NADH metabolic process)|go:"GO:0016746"(acyltransferase activity)|go:"GO:0031072"(heat shock protein binding)|go:"GO:0033512"(L-lysine catabolic process to acetyl-CoA via saccharopine)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0045252"(oxoglutarate dehydrogenase complex)|go:"GO:0051087"(chaperone binding)|go:"GO:0106077"(histone succinylation)|reactome:R-RNO-389661|reactome:R-RNO-71064|reactome:R-RNO-71403	-	-	-	figure legend:st1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10116(rat-hippocampus)|taxid:10116(Rattus norvegicus hippocampal neurons)	-	2020/10/30	2020/10/30	rogid:DtE+ZXAZKdCMvUW5K+jXQ5bH07M10116	rogid:Ytjw7Tvj7aVaGmQksyMIBlweGUk10116	rigid:zzsc1zNhBb5nwIRPeFpYOKgC3M8	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q5XIE8	uniprotkb:P20788	intact:EBI-15348306|ensembl:ENSRNOP00000023037	intact:EBI-931318|uniprotkb:Q6QI13|ensembl:ENSRNOP00000024609	psi-mi:itm2b_rat(display_long)|uniprotkb:Itm2b(gene name)|psi-mi:Itm2b(display_short)|uniprotkb:Immature BRI2(gene name synonym)|uniprotkb:Transmembrane protein BRI(gene name synonym)	psi-mi:ucri_rat(display_long)|uniprotkb:Rieske protein UQCRFS1(gene name synonym)|uniprotkb:Uqcrfs1(gene name)|psi-mi:Uqcrfs1(display_short)|uniprotkb:Ubiquinol-cytochrome c reductase iron-sulfur subunit(gene name synonym)|uniprotkb:Rieske iron-sulfur protein(gene name synonym)|uniprotkb:Complex III subunit 5(gene name synonym)|uniprotkb:Liver regeneration-related protein LRRGT00195(gene name synonym)|uniprotkb:Cytochrome b-c1 complex subunit 5(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Martins et al. (2018)	imex:IM-28469|pubmed:29476059	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26440627|imex:IM-28469-5	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSRNOG00000016271(gene)|ensembl:ENSRNOT00000023037(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001540"(amyloid-beta binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0010008"(endosome membrane)|go:"GO:0030660"(Golgi-associated vesicle membrane)|go:"GO:0031301"(integral component of organelle membrane)|go:"GO:0042985"(negative regulation of amyloid precursor protein biosynthetic process)|interpro:IPR007084(BRICHOS)|interpro:IPR040145|mint:Q5XIE8|refseq:NP_001006964.1|rgd:620727	rgd:628838|refseq:NP_001008888.1|ensembl:ENSRNOG00000018281(gene)|ensembl:ENSRNOT00000024609(transcript)|go:"GO:0005739"(mitochondrion)|go:"GO:0005750"(mitochondrial respiratory chain complex III)|go:"GO:0005751"(mitochondrial respiratory chain complex IV)|go:"GO:0008121"(ubiquinol-cytochrome-c reductase activity)|go:"GO:0009725"(response to hormone)|go:"GO:0016491"(oxidoreductase activity)|go:"GO:0022904"(respiratory electron transport chain)|go:"GO:0031966"(mitochondrial membrane)|go:"GO:0034551"(mitochondrial respiratory chain complex III assembly)|go:"GO:0042493"|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045275"(respiratory chain complex III)|go:"GO:0046677"(response to antibiotic)|go:"GO:0046872"(metal ion binding)|go:"GO:0051537"(2 iron, 2 sulfur cluster binding)|interpro:IPR004192(Ubiquinol cytochrome reductase transmembrane region)|interpro:IPR005805(Rieske iron-sulphur protein, C-terminal)|interpro:IPR006317(Ubiquinol-cytochrome c reductase, iron-sulphur subunit)|interpro:IPR011070(Globular protein, non-globular alpha/beta subunit)|interpro:IPR014349(Rieske iron-sulphur protein)|interpro:IPR015248(Ubiquinol-cytochrome c reductase 8 kDa, N-terminal)|interpro:IPR017941|interpro:IPR036922|interpro:IPR037008|mint:P20788|reactome:R-RNO-611105	-	-	-	figure legend:st1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10116(rat-hippocampus)|taxid:10116(Rattus norvegicus hippocampal neurons)	-	2020/10/30	2020/10/30	rogid:DtE+ZXAZKdCMvUW5K+jXQ5bH07M10116	rogid:MLzi+0uooHySBqxsDJ7MItr9r8E10116	rigid:zzsc1zNhBb5nwIRPeFpYOKgC3M8	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q5XIE8	uniprotkb:P13233	intact:EBI-15348306|ensembl:ENSRNOP00000023037	intact:EBI-2640672|uniprotkb:Q4V796|uniprotkb:Q64575|ensembl:ENSRNOP00000023875	psi-mi:itm2b_rat(display_long)|uniprotkb:Itm2b(gene name)|psi-mi:Itm2b(display_short)|uniprotkb:Immature BRI2(gene name synonym)|uniprotkb:Transmembrane protein BRI(gene name synonym)	psi-mi:cn37_rat(display_long)|uniprotkb:Cnp(gene name)|psi-mi:Cnp(display_short)|uniprotkb:Cnp1(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Martins et al. (2018)	imex:IM-28469|pubmed:29476059	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26440627|imex:IM-28469-5	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSRNOG00000016271(gene)|ensembl:ENSRNOT00000023037(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001540"(amyloid-beta binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0010008"(endosome membrane)|go:"GO:0030660"(Golgi-associated vesicle membrane)|go:"GO:0031301"(integral component of organelle membrane)|go:"GO:0042985"(negative regulation of amyloid precursor protein biosynthetic process)|interpro:IPR007084(BRICHOS)|interpro:IPR040145|mint:Q5XIE8|refseq:NP_001006964.1|rgd:620727	rgd:2368|refseq:NP_036941.1|ensembl:ENSRNOG00000017496(gene)|ensembl:ENSRNOT00000023872(transcript)|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0003723"(RNA binding)|go:"GO:0004113"(2',3'-cyclic-nucleotide 3'-phosphodiesterase activity)|go:"GO:0005615"(extracellular space)|go:"GO:0005737"(cytoplasm)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005886"(plasma membrane)|go:"GO:0005902"(microvillus)|go:"GO:0007409"(axonogenesis)|go:"GO:0007568"(aging)|go:"GO:0008344"(adult locomotory behavior)|go:"GO:0009214"(cyclic nucleotide catabolic process)|go:"GO:0009636"(response to toxic substance)|go:"GO:0016020"(membrane)|go:"GO:0030551"(cyclic nucleotide binding)|go:"GO:0030900"(forebrain development)|go:"GO:0031143"(pseudopodium)|go:"GO:0032496"(response to lipopolysaccharide)|go:"GO:0035748"(myelin sheath abaxonal region)|go:"GO:0035749"(myelin sheath adaxonal region)|go:"GO:0042470"(melanosome)|go:"GO:0042995"(cell projection)|go:"GO:0043209"(myelin sheath)|go:"GO:0046902"(regulation of mitochondrial membrane permeability)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0048709"(oligodendrocyte differentiation)|interpro:IPR008431(Cyclic nucleotide phosphodiesterase)|interpro:IPR009097(RNA ligase/cyclic nucleotide phosphodiesterase)|interpro:IPR027417|mint:P13233|rcsb pdb:2ILX	-	-	-	figure legend:st1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10116(rat-hippocampus)|taxid:10116(Rattus norvegicus hippocampal neurons)	-	2020/10/30	2020/10/30	rogid:DtE+ZXAZKdCMvUW5K+jXQ5bH07M10116	rogid:+0AAow8yyo0d6aKTghtTmcS2SZw10116	rigid:zzsc1zNhBb5nwIRPeFpYOKgC3M8	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q5XIE8	uniprotkb:P01830	intact:EBI-15348306|ensembl:ENSRNOP00000023037	intact:EBI-2255860|ensembl:ENSRNOP00000008685	psi-mi:itm2b_rat(display_long)|uniprotkb:Itm2b(gene name)|psi-mi:Itm2b(display_short)|uniprotkb:Immature BRI2(gene name synonym)|uniprotkb:Transmembrane protein BRI(gene name synonym)	psi-mi:thy1_rat(display_long)|uniprotkb:Thy1(gene name)|psi-mi:Thy1(display_short)|uniprotkb:Thy-1(gene name synonym)|uniprotkb:Thy-1 antigen(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Martins et al. (2018)	imex:IM-28469|pubmed:29476059	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26440627|imex:IM-28469-5	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSRNOG00000016271(gene)|ensembl:ENSRNOT00000023037(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001540"(amyloid-beta binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0010008"(endosome membrane)|go:"GO:0030660"(Golgi-associated vesicle membrane)|go:"GO:0031301"(integral component of organelle membrane)|go:"GO:0042985"(negative regulation of amyloid precursor protein biosynthetic process)|interpro:IPR007084(BRICHOS)|interpro:IPR040145|mint:Q5XIE8|refseq:NP_001006964.1|rgd:620727	rgd:3860|refseq:NP_036805.1|dip:DIP-1031N|ensembl:ENSRNOG00000006604(gene)|ensembl:ENSRNOT00000008685(transcript)|go:"GO:0001525"(angiogenesis)|go:"GO:0001952"(regulation of cell-matrix adhesion)|go:"GO:0002693"(positive regulation of cellular extravasation)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005178"(integrin binding)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006469"(negative regulation of protein kinase activity)|go:"GO:0007010"(cytoskeleton organization)|go:"GO:0007229"(integrin-mediated signaling pathway)|go:"GO:0007267"(cell-cell signaling)|go:"GO:0009897"(external side of plasma membrane)|go:"GO:0009986"(cell surface)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0019899"(enzyme binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030336"(negative regulation of cell migration)|go:"GO:0030425"(dendrite)|go:"GO:0030426"(growth cone)|go:"GO:0030673"(axolemma)|go:"GO:0031362"(anchored component of external side of plasma membrane)|go:"GO:0032590"(dendrite membrane)|go:"GO:0032809"(neuronal cell body membrane)|go:"GO:0034116"(positive regulation of heterotypic cell-cell adhesion)|go:"GO:0034235"(GPI anchor binding)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043113"(receptor clustering)|go:"GO:0043547"(positive regulation of GTPase activity)|go:"GO:0045121"(membrane raft)|go:"GO:0045576"(mast cell activation)|go:"GO:0046549"(retinal cone cell development)|go:"GO:0046658"(anchored component of plasma membrane)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0048041"(focal adhesion assembly)|go:"GO:0048147"(negative regulation of fibroblast proliferation)|go:"GO:0050731"(positive regulation of peptidyl-tyrosine phosphorylation)|go:"GO:0050771"(negative regulation of axonogenesis)|go:"GO:0050852"(T cell receptor signaling pathway)|go:"GO:0050860"(negative regulation of T cell receptor signaling pathway)|go:"GO:0050870"(positive regulation of T cell activation)|go:"GO:0051281"(positive regulation of release of sequestered calcium ion into cytosol)|go:"GO:0051894"(positive regulation of focal adhesion assembly)|go:"GO:0061099"(negative regulation of protein tyrosine kinase activity)|go:"GO:0070571"(negative regulation of neuron projection regeneration)|go:"GO:0098609"(cell-cell adhesion)|go:"GO:2000298"(regulation of Rho-dependent protein serine/threonine kinase activity)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR013106(Immunoglobulin V-set)|interpro:IPR013151(Immunoglobulin)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR033292|interpro:IPR036179|mint:P01830|reactome:R-RNO-163125	-	-	-	figure legend:st1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10116(rat-hippocampus)|taxid:10116(Rattus norvegicus hippocampal neurons)	-	2020/10/30	2020/10/30	rogid:DtE+ZXAZKdCMvUW5K+jXQ5bH07M10116	rogid:P4seZqeNePRK65KZGl6CVdenFHk10116	rigid:zzsc1zNhBb5nwIRPeFpYOKgC3M8	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q5XIE8	uniprotkb:Q6P502	intact:EBI-15348306|ensembl:ENSRNOP00000023037	intact:EBI-918953|ensembl:ENSRNOP00000025824	psi-mi:itm2b_rat(display_long)|uniprotkb:Itm2b(gene name)|psi-mi:Itm2b(display_short)|uniprotkb:Immature BRI2(gene name synonym)|uniprotkb:Transmembrane protein BRI(gene name synonym)	psi-mi:tcpg_rat(display_long)|uniprotkb:Cct3(gene name)|psi-mi:Cct3(display_short)|uniprotkb:CCT-gamma(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Martins et al. (2018)	imex:IM-28469|pubmed:29476059	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26440627|imex:IM-28469-5	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSRNOG00000016271(gene)|ensembl:ENSRNOT00000023037(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001540"(amyloid-beta binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0010008"(endosome membrane)|go:"GO:0030660"(Golgi-associated vesicle membrane)|go:"GO:0031301"(integral component of organelle membrane)|go:"GO:0042985"(negative regulation of amyloid precursor protein biosynthetic process)|interpro:IPR007084(BRICHOS)|interpro:IPR040145|mint:Q5XIE8|refseq:NP_001006964.1|rgd:620727	rgd:735038|refseq:NP_954522.1|ensembl:ENSRNOG00000019090(gene)|ensembl:ENSRNOT00000025824(transcript)|go:"GO:0002199"(zona pellucida receptor complex)|go:"GO:0005524"(ATP binding)|go:"GO:0005832"(chaperonin-containing T-complex)|go:"GO:0005874"(microtubule)|go:"GO:0006457"(protein folding)|go:"GO:0007339"(binding of sperm to zona pellucida)|go:"GO:0032212"(positive regulation of telomere maintenance via telomerase)|go:"GO:0044183"(protein folding chaperone)|go:"GO:0044297"(cell body)|go:"GO:0046931"(pore complex assembly)|go:"GO:0050821"(protein stabilization)|go:"GO:0051082"(unfolded protein binding)|go:"GO:1901998"(toxin transport)|go:"GO:1904851"(positive regulation of establishment of protein localization to telomere)|interpro:IPR002194(Chaperonin TCP-1, conserved site)|interpro:IPR002423(Chaperonin Cpn60/TCP-1)|interpro:IPR012719(T-complex protein 1, gamma subunit)|interpro:IPR017998|interpro:IPR027409|interpro:IPR027410|interpro:IPR027413|mint:Q6P502|reactome:R-RNO-390471|reactome:R-RNO-5620922|reactome:R-RNO-6814122	-	-	-	figure legend:st1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10116(rat-hippocampus)|taxid:10116(Rattus norvegicus hippocampal neurons)	-	2020/10/30	2020/10/30	rogid:DtE+ZXAZKdCMvUW5K+jXQ5bH07M10116	rogid:1JIKeXK/jQ/vqkYLjBGcrCj1PDg10116	rigid:zzsc1zNhBb5nwIRPeFpYOKgC3M8	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q5XIE8	uniprotkb:Q7TPB1	intact:EBI-15348306|ensembl:ENSRNOP00000023037	intact:EBI-919426|ensembl:ENSRNOP00000012847	psi-mi:itm2b_rat(display_long)|uniprotkb:Itm2b(gene name)|psi-mi:Itm2b(display_short)|uniprotkb:Immature BRI2(gene name synonym)|uniprotkb:Transmembrane protein BRI(gene name synonym)	psi-mi:tcpd_rat(display_long)|uniprotkb:Cct4(gene name)|psi-mi:Cct4(display_short)|uniprotkb:CCT-delta(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Martins et al. (2018)	imex:IM-28469|pubmed:29476059	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26440627|imex:IM-28469-5	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSRNOG00000016271(gene)|ensembl:ENSRNOT00000023037(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001540"(amyloid-beta binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0010008"(endosome membrane)|go:"GO:0030660"(Golgi-associated vesicle membrane)|go:"GO:0031301"(integral component of organelle membrane)|go:"GO:0042985"(negative regulation of amyloid precursor protein biosynthetic process)|interpro:IPR007084(BRICHOS)|interpro:IPR040145|mint:Q5XIE8|refseq:NP_001006964.1|rgd:620727	rgd:727937|refseq:NP_877966.1|ensembl:ENSRNOG00000009642(gene)|ensembl:ENSRNOT00000012847(transcript)|go:"GO:0002199"(zona pellucida receptor complex)|go:"GO:0005524"(ATP binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005832"(chaperonin-containing T-complex)|go:"GO:0005874"(microtubule)|go:"GO:0005929"(cilium)|go:"GO:0006457"(protein folding)|go:"GO:0007339"(binding of sperm to zona pellucida)|go:"GO:0032212"(positive regulation of telomere maintenance via telomerase)|go:"GO:0042470"(melanosome)|go:"GO:0044183"(protein folding chaperone)|go:"GO:0044297"(cell body)|go:"GO:0050821"(protein stabilization)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0051973"(positive regulation of telomerase activity)|go:"GO:0090666"(scaRNA localization to Cajal body)|go:"GO:1901998"(toxin transport)|go:"GO:1904851"(positive regulation of establishment of protein localization to telomere)|go:"GO:1904874"(positive regulation of telomerase RNA localization to Cajal body)|interpro:IPR002194(Chaperonin TCP-1, conserved site)|interpro:IPR002423(Chaperonin Cpn60/TCP-1)|interpro:IPR012717(T-complex protein 1, delta subunit)|interpro:IPR017998|interpro:IPR027409|interpro:IPR027410|interpro:IPR027413|mint:Q7TPB1|reactome:R-RNO-390471|reactome:R-RNO-5620922|reactome:R-RNO-6814122	-	-	-	figure legend:st1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10116(rat-hippocampus)|taxid:10116(Rattus norvegicus hippocampal neurons)	-	2020/10/30	2020/10/30	rogid:DtE+ZXAZKdCMvUW5K+jXQ5bH07M10116	rogid:xYiR/DP4M2RW1MeQwg2Sb9M77xc10116	rigid:zzsc1zNhBb5nwIRPeFpYOKgC3M8	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q5XIE8	uniprotkb:Q5XIM9	intact:EBI-15348306|ensembl:ENSRNOP00000023037	intact:EBI-920517|ensembl:ENSRNOP00000029234	psi-mi:itm2b_rat(display_long)|uniprotkb:Itm2b(gene name)|psi-mi:Itm2b(display_short)|uniprotkb:Immature BRI2(gene name synonym)|uniprotkb:Transmembrane protein BRI(gene name synonym)	psi-mi:tcpb_rat(display_long)|uniprotkb:Cct2(gene name)|psi-mi:Cct2(display_short)|uniprotkb:CCT-beta(gene name synonym)|uniprotkb:Cctb(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Martins et al. (2018)	imex:IM-28469|pubmed:29476059	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26440627|imex:IM-28469-5	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSRNOG00000016271(gene)|ensembl:ENSRNOT00000023037(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001540"(amyloid-beta binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0010008"(endosome membrane)|go:"GO:0030660"(Golgi-associated vesicle membrane)|go:"GO:0031301"(integral component of organelle membrane)|go:"GO:0042985"(negative regulation of amyloid precursor protein biosynthetic process)|interpro:IPR007084(BRICHOS)|interpro:IPR040145|mint:Q5XIE8|refseq:NP_001006964.1|rgd:620727	rgd:1359143|refseq:NP_001005905.1|ensembl:ENSRNOG00000021317(gene)|ensembl:ENSRNOT00000037946(transcript)|go:"GO:0002199"(zona pellucida receptor complex)|go:"GO:0005524"(ATP binding)|go:"GO:0005832"(chaperonin-containing T-complex)|go:"GO:0005874"(microtubule)|go:"GO:0006457"(protein folding)|go:"GO:0007339"(binding of sperm to zona pellucida)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032212"(positive regulation of telomere maintenance via telomerase)|go:"GO:0044183"(protein folding chaperone)|go:"GO:0044297"(cell body)|go:"GO:0050821"(protein stabilization)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0051086"(chaperone mediated protein folding independent of cofactor)|go:"GO:0051131"(chaperone-mediated protein complex assembly)|go:"GO:0051973"(positive regulation of telomerase activity)|go:"GO:0090666"(scaRNA localization to Cajal body)|go:"GO:1901998"(toxin transport)|go:"GO:1904851"(positive regulation of establishment of protein localization to telomere)|go:"GO:1904874"(positive regulation of telomerase RNA localization to Cajal body)|interpro:IPR002194(Chaperonin TCP-1, conserved site)|interpro:IPR002423(Chaperonin Cpn60/TCP-1)|interpro:IPR012716(T-complex protein 1, beta subunit)|interpro:IPR017998|interpro:IPR027409|interpro:IPR027410|interpro:IPR027413|mint:Q5XIM9|reactome:R-RNO-390471|reactome:R-RNO-5620922|reactome:R-RNO-6798695|reactome:R-RNO-6814122|reactome:R-RNO-9013418|reactome:R-RNO-9013422	-	-	-	figure legend:st1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10116(rat-hippocampus)|taxid:10116(Rattus norvegicus hippocampal neurons)	-	2020/10/30	2020/10/30	rogid:DtE+ZXAZKdCMvUW5K+jXQ5bH07M10116	rogid:JKr4ca8SpJ/EnpoJsDazwn8L6hc10116	rigid:zzsc1zNhBb5nwIRPeFpYOKgC3M8	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q5XIE8	uniprotkb:P60881	intact:EBI-15348306|ensembl:ENSRNOP00000023037	intact:EBI-1027214|uniprotkb:P13795|uniprotkb:P36974|uniprotkb:P70557|uniprotkb:P70558|uniprotkb:Q8IXK3|uniprotkb:Q96FM2|uniprotkb:Q9BR45|intact:EBI-11701410	psi-mi:itm2b_rat(display_long)|uniprotkb:Itm2b(gene name)|psi-mi:Itm2b(display_short)|uniprotkb:Immature BRI2(gene name synonym)|uniprotkb:Transmembrane protein BRI(gene name synonym)	psi-mi:snp25_rat(display_long)|uniprotkb:Snap25(gene name)|psi-mi:Snap25(display_short)|uniprotkb:Snap(gene name synonym)|uniprotkb:Synaptosomal-associated 25 kDa protein(gene name synonym)|uniprotkb:Super protein(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Martins et al. (2018)	imex:IM-28469|pubmed:29476059	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26440627|imex:IM-28469-5	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSRNOG00000016271(gene)|ensembl:ENSRNOT00000023037(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001540"(amyloid-beta binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0010008"(endosome membrane)|go:"GO:0030660"(Golgi-associated vesicle membrane)|go:"GO:0031301"(integral component of organelle membrane)|go:"GO:0042985"(negative regulation of amyloid precursor protein biosynthetic process)|interpro:IPR007084(BRICHOS)|interpro:IPR040145|mint:Q5XIE8|refseq:NP_001006964.1|rgd:620727	go:"GO:0000149"(SNARE binding)|go:"GO:0001917"(photoreceptor inner segment)|go:"GO:0005249"(voltage-gated potassium channel activity)|go:"GO:0005484"(SNAP receptor activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005886"(plasma membrane)|go:"GO:0006887"(exocytosis)|go:"GO:0006906"(vesicle fusion)|go:"GO:0007269"(neurotransmitter secretion)|go:"GO:0007409"(axonogenesis)|go:"GO:0007616"(long-term memory)|go:"GO:0007626"(locomotory behavior)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0008076"(voltage-gated potassium channel complex)|go:"GO:0008306"(associative learning)|go:"GO:0010975"(regulation of neuron projection development)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0016020"(membrane)|go:"GO:0016079"(synaptic vesicle exocytosis)|go:"GO:0016082"(synaptic vesicle priming)|go:"GO:0016197"(endosomal transport)|go:"GO:0017022"(myosin binding)|go:"GO:0017075"(syntaxin-1 binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0019905"(syntaxin binding)|go:"GO:0030027"(lamellipodium)|go:"GO:0030175"(filopodium)|go:"GO:0030182"(neuron differentiation)|go:"GO:0030252"(growth hormone secretion)|go:"GO:0030424"(axon)|go:"GO:0030426"(growth cone)|go:"GO:0030431"(sleep)|go:"GO:0031201"(SNARE complex)|go:"GO:0031234"(extrinsic component of cytoplasmic side of plasma membrane)|go:"GO:0031629"(synaptic vesicle fusion to presynaptic active zone membrane)|go:"GO:0032024"(positive regulation of insulin secretion)|go:"GO:0035493"(SNARE complex assembly)|go:"GO:0036477"(somatodendritic compartment)|go:"GO:0042734"(presynaptic membrane)|go:"GO:0043005"(neuron projection)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043195"(terminal bouton)|go:"GO:0043229"(intracellular organelle)|go:"GO:0044295"(axonal growth cone)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0045121"(membrane raft)|go:"GO:0045202"(synapse)|go:"GO:0046887"(positive regulation of hormone secretion)|go:"GO:0047485"(protein N-terminus binding)|go:"GO:0048306"(calcium-dependent protein binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0048787"(presynaptic active zone membrane)|go:"GO:0048791"(calcium ion-regulated exocytosis of neurotransmitter)|go:"GO:0051963"(regulation of synapse assembly)|go:"GO:0070032"(synaptobrevin 2-SNAP-25-syntaxin-1a-complexin I complex)|go:"GO:0070033"(synaptobrevin 2-SNAP-25-syntaxin-1a-complexin II complex)|go:"GO:0070044"(synaptobrevin 2-SNAP-25-syntaxin-1a complex)|go:"GO:0070201"(regulation of establishment of protein localization)|go:"GO:0098794"(postsynapse)|go:"GO:0098967"(exocytic insertion of neurotransmitter receptor to postsynaptic membrane)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099026"(anchored component of presynaptic membrane)|go:"GO:0099590"(neurotransmitter receptor internalization)|interpro:IPR000727(Target SNARE coiled-coil region)|interpro:IPR000928(SNAP-25)|interpro:IPR039077|rcsb pdb:1JTH|rcsb pdb:1N7S|rcsb pdb:1SFC|rcsb pdb:1URQ|rcsb pdb:3HD7|rcsb pdb:3IPD|rcsb pdb:3J96|rcsb pdb:3J97|rcsb pdb:3J98|rcsb pdb:3J99|rcsb pdb:5CCG|rcsb pdb:5CCH|rcsb pdb:5CCI|rcsb pdb:5KJ7|rcsb pdb:5KJ8|rcsb pdb:5LOB|rcsb pdb:5LOW|rcsb pdb:5W5C|rcsb pdb:5W5D|rcsb pdb:6IP1|rcsb pdb:6MDM|rcsb pdb:6MDN|rcsb pdb:6MDO|rcsb pdb:6MDP|go:"GO:0060291"(long-term synaptic potentiation)|rcsb pdb:6MTI|rcsb pdb:6WVW|reactome:R-RNO-181429|reactome:R-RNO-181430|reactome:R-RNO-210500|reactome:R-RNO-212676|reactome:R-RNO-264642|reactome:R-RNO-449836|reactome:R-RNO-6798695|reactome:R-RNO-888590|rgd:3728|refseq:NP_112253.1|refseq:NP_001257504.1|refseq:NP_001257505.1|mint:P60881|dip:DIP-29205N	-	-	-	figure legend:st1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10116(rat-hippocampus)|taxid:10116(Rattus norvegicus hippocampal neurons)	-	2020/10/30	2020/10/30	rogid:DtE+ZXAZKdCMvUW5K+jXQ5bH07M10116	rogid:/Z7IJEKvHKJbZS4f4oDDyluztHs10116	rigid:zzsc1zNhBb5nwIRPeFpYOKgC3M8	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q5XIE8	uniprotkb:P50399	intact:EBI-15348306|ensembl:ENSRNOP00000023037	intact:EBI-8848546|uniprotkb:Q6P797|ensembl:ENSRNOP00000024952	psi-mi:itm2b_rat(display_long)|uniprotkb:Itm2b(gene name)|psi-mi:Itm2b(display_short)|uniprotkb:Immature BRI2(gene name synonym)|uniprotkb:Transmembrane protein BRI(gene name synonym)	psi-mi:gdib_rat(display_long)|uniprotkb:Gdi2(gene name)|psi-mi:Gdi2(display_short)|uniprotkb:Gdi3(gene name synonym)|uniprotkb:GDI-3(gene name synonym)|uniprotkb:Guanosine diphosphate dissociation inhibitor 2(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Martins et al. (2018)	imex:IM-28469|pubmed:29476059	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26440627|imex:IM-28469-5	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSRNOG00000016271(gene)|ensembl:ENSRNOT00000023037(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001540"(amyloid-beta binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0010008"(endosome membrane)|go:"GO:0030660"(Golgi-associated vesicle membrane)|go:"GO:0031301"(integral component of organelle membrane)|go:"GO:0042985"(negative regulation of amyloid precursor protein biosynthetic process)|interpro:IPR007084(BRICHOS)|interpro:IPR040145|mint:Q5XIE8|refseq:NP_001006964.1|rgd:620727	refseq:NP_058972.2|rgd:61802|ensembl:ENSRNOG00000018091(gene)|ensembl:ENSRNOT00000024952(transcript)|go:"GO:0005093"(Rab GDP-dissociation inhibitor activity)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0007264"(small GTPase mediated signal transduction)|go:"GO:0015031"(protein transport)|go:"GO:0016020"(membrane)|go:"GO:0016192"(vesicle-mediated transport)|go:"GO:0031267"(small GTPase binding)|go:"GO:0045202"(synapse)|interpro:IPR000806(Rab GDI protein)|interpro:IPR018203|interpro:IPR036188|mint:P50399|reactome:R-RNO-6798695|reactome:R-RNO-8876198	-	-	-	figure legend:st1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10116(rat-hippocampus)|taxid:10116(Rattus norvegicus hippocampal neurons)	-	2020/10/30	2020/10/30	rogid:DtE+ZXAZKdCMvUW5K+jXQ5bH07M10116	rogid:+ngZz9q02lDEdFO543w/yl6chgc10116	rigid:zzsc1zNhBb5nwIRPeFpYOKgC3M8	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q5XIE8	uniprotkb:P16409	intact:EBI-15348306|ensembl:ENSRNOP00000023037	intact:EBI-26438054|ensembl:ENSRNOP00000028458	psi-mi:itm2b_rat(display_long)|uniprotkb:Itm2b(gene name)|psi-mi:Itm2b(display_short)|uniprotkb:Immature BRI2(gene name synonym)|uniprotkb:Transmembrane protein BRI(gene name synonym)	psi-mi:myl3_rat(display_long)|uniprotkb:Myl3(gene name)|psi-mi:Myl3(display_short)|uniprotkb:Mlc1v(gene name synonym)|uniprotkb:Myosin alkali light chain 1, ventricular(gene name synonym)|uniprotkb:Myosin light chain 1, slow-twitch muscle B/ventricular isoform(gene name synonym)|uniprotkb:Ventricular myosin light chain 1(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Martins et al. (2018)	imex:IM-28469|pubmed:29476059	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26440627|imex:IM-28469-5	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSRNOG00000016271(gene)|ensembl:ENSRNOT00000023037(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001540"(amyloid-beta binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0010008"(endosome membrane)|go:"GO:0030660"(Golgi-associated vesicle membrane)|go:"GO:0031301"(integral component of organelle membrane)|go:"GO:0042985"(negative regulation of amyloid precursor protein biosynthetic process)|interpro:IPR007084(BRICHOS)|interpro:IPR040145|mint:Q5XIE8|refseq:NP_001006964.1|rgd:620727	ensembl:ENSRNOT00000028458(transcript)|go:"GO:0002026"(regulation of the force of heart contraction)|go:"GO:0003774"(cytoskeletal motor activity)|go:"GO:0003785"(actin monomer binding)|go:"GO:0005509"(calcium ion binding)|go:"GO:0006936"(muscle contraction)|go:"GO:0006942"(regulation of striated muscle contraction)|go:"GO:0007519"(skeletal muscle tissue development)|go:"GO:0016459"(myosin complex)|go:"GO:0031672"(A band)|go:"GO:0031674"(I band)|go:"GO:0055010"(ventricular cardiac muscle tissue morphogenesis)|go:"GO:0060048"(cardiac muscle contraction)|interpro:IPR002048(Calcium-binding EF-hand)|interpro:IPR011992(EF-Hand type)|mint:P16409|reactome:R-RNO-390522|ensembl:ENSRNOG00000020955(gene)|refseq:NP_036738.1|refseq:XP_006243979.3|rgd:3142	-	-	-	figure legend:st1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10116(rat-hippocampus)|taxid:10116(Rattus norvegicus hippocampal neurons)	-	2020/10/30	2020/10/30	rogid:DtE+ZXAZKdCMvUW5K+jXQ5bH07M10116	rogid:zxLulGJOfj/nNh15aQrPvpoFsWc10116	rigid:zzsc1zNhBb5nwIRPeFpYOKgC3M8	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q5XIE8	uniprotkb:Q5RKI1	intact:EBI-15348306|ensembl:ENSRNOP00000023037	intact:EBI-22250960|ensembl:ENSRNOP00000002484	psi-mi:itm2b_rat(display_long)|uniprotkb:Itm2b(gene name)|psi-mi:Itm2b(display_short)|uniprotkb:Immature BRI2(gene name synonym)|uniprotkb:Transmembrane protein BRI(gene name synonym)	psi-mi:if4a2_rat(display_long)|uniprotkb:ATP-dependent RNA helicase eIF4A-2(gene name synonym)|uniprotkb:Eif4a2(gene name)|psi-mi:Eif4a2(display_short)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Martins et al. (2018)	imex:IM-28469|pubmed:29476059	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26440627|imex:IM-28469-5	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSRNOG00000016271(gene)|ensembl:ENSRNOT00000023037(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001540"(amyloid-beta binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0010008"(endosome membrane)|go:"GO:0030660"(Golgi-associated vesicle membrane)|go:"GO:0031301"(integral component of organelle membrane)|go:"GO:0042985"(negative regulation of amyloid precursor protein biosynthetic process)|interpro:IPR007084(BRICHOS)|interpro:IPR040145|mint:Q5XIE8|refseq:NP_001006964.1|rgd:620727	ensembl:ENSRNOG00000001815(gene)|ensembl:ENSRNOT00000002484(transcript)|go:"GO:0002183"(cytoplasmic translational initiation)|go:"GO:0003743"(translation initiation factor activity)|go:"GO:0005524"(ATP binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|go:"GO:1900260"(negative regulation of RNA-directed 5'-3' RNA polymerase activity)|go:"GO:1990830"(cellular response to leukemia inhibitory factor)|interpro:IPR000629(RNA helicase, ATP-dependent, DEAD-box, conserved site)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR011545(DNA/RNA helicase, DEAD/DEAH box type, N-terminal)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR014014(RNA helicase, DEAD-box type, Q motif)|interpro:IPR027417|interpro:IPR044728|mint:Q5RKI1|reactome:R-RNO-1169408|reactome:R-RNO-156827|reactome:R-RNO-429947|reactome:R-RNO-72649|reactome:R-RNO-72662|reactome:R-RNO-72702|reactome:R-RNO-72706|go:"GO:0003724"(RNA helicase activity)|refseq:NP_001008336.1|rgd:1309225	-	-	-	figure legend:st1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10116(rat-hippocampus)|taxid:10116(Rattus norvegicus hippocampal neurons)	-	2020/10/30	2020/10/30	rogid:DtE+ZXAZKdCMvUW5K+jXQ5bH07M10116	rogid:m9i/jWfsbU+6kQvj1h06x31+awg10116	rigid:zzsc1zNhBb5nwIRPeFpYOKgC3M8	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q5XIE8	uniprotkb:P62161	intact:EBI-15348306|ensembl:ENSRNOP00000023037	intact:EBI-397530|uniprotkb:P02593|uniprotkb:P70667|uniprotkb:P99014|uniprotkb:Q61379|uniprotkb:Q61380|dip:DIP-29528N|refseq:NP_059022|uniprotkb:P0DP30	psi-mi:itm2b_rat(display_long)|uniprotkb:Itm2b(gene name)|psi-mi:Itm2b(display_short)|uniprotkb:Immature BRI2(gene name synonym)|uniprotkb:Transmembrane protein BRI(gene name synonym)	psi-mi:calm_rat(display_long)|uniprotkb:Calm1(gene name)|psi-mi:Calm1(display_short)|uniprotkb:Calm(gene name synonym)|uniprotkb:Cam(gene name synonym)|uniprotkb:Cam1(gene name synonym)|uniprotkb:Calm2(gene name)|psi-mi:Calm2(display_short)|uniprotkb:Cam2(gene name synonym)|uniprotkb:Camb(gene name synonym)|uniprotkb:Calm3(gene name)|psi-mi:Calm3(display_short)|uniprotkb:Cam3(gene name synonym)|uniprotkb:Camc(gene name synonym)|uniprotkb:CaMII(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Martins et al. (2018)	imex:IM-28469|pubmed:29476059	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26440627|imex:IM-28469-5	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSRNOG00000016271(gene)|ensembl:ENSRNOT00000023037(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001540"(amyloid-beta binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0010008"(endosome membrane)|go:"GO:0030660"(Golgi-associated vesicle membrane)|go:"GO:0031301"(integral component of organelle membrane)|go:"GO:0042985"(negative regulation of amyloid precursor protein biosynthetic process)|interpro:IPR007084(BRICHOS)|interpro:IPR040145|mint:Q5XIE8|refseq:NP_001006964.1|rgd:620727	rcsb pdb:4G27|rcsb pdb:4G28|go:"GO:0030426"(growth cone)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0047485"(protein N-terminus binding)|go:"GO:0050998"(nitric-oxide synthase binding)|go:"GO:0051000"(positive regulation of nitric-oxide synthase activity)|go:"GO:0060314"(regulation of ryanodine-sensitive calcium-release channel activity)|go:"GO:1901339"(regulation of store-operated calcium channel activity)|go:"GO:1901841"(regulation of high voltage-gated calcium channel activity)|rcsb pdb:4I2Y|rcsb pdb:4IL1|go:"GO:0007190"(activation of adenylate cyclase activity)|go:"GO:0008179"(adenylate cyclase binding)|go:"GO:0019722"(calcium-mediated signaling)|go:"GO:0030235"(nitric-oxide synthase regulator activity)|rcsb pdb:4RJD|go:"GO:0000922"(spindle pole)|go:"GO:0005246"(calcium channel regulator activity)|rgd:2257|rgd:2258|rgd:2259|refseq:NP_036650.1|refseq:NP_059022.1|refseq:NP_114175.1|interpro:IPR011992(EF-Hand type)|interpro:IPR018247|interpro:IPR002048(Calcium-binding EF-hand)|rcsb pdb:1G4Y|rcsb pdb:1NIW|rcsb pdb:1QX5|rcsb pdb:1QX7|rcsb pdb:2HQW|rcsb pdb:2PQ3|rcsb pdb:3B32|rcsb pdb:3BXK|rcsb pdb:3BXL|rcsb pdb:3CLN|rcsb pdb:3EK4|rcsb pdb:3EK7|rcsb pdb:3EK8|rcsb pdb:3EKH|rcsb pdb:3EKJ|rcsb pdb:3EVR|rcsb pdb:3EVU|rcsb pdb:3EVV|rcsb pdb:3IFK|rcsb pdb:3SG2|rcsb pdb:3SG3|rcsb pdb:3SG4|rcsb pdb:3SG5|rcsb pdb:3SG6|rcsb pdb:3SG7|rcsb pdb:3SJQ|rcsb pdb:4QNH|go:"GO:0005509"(calcium ion binding)|reactome:R-RNO-2672351|reactome:R-RNO-418359|reactome:R-RNO-425561|reactome:R-RNO-5576892|reactome:R-RNO-5578775|reactome:R-RNO-936837|rcsb pdb:4OY4|go:"GO:0005829"(cytosol)|rcsb pdb:2YGG|go:"GO:0005886"(plasma membrane)|go:"GO:0002027"(regulation of heart rate)|go:"GO:0005513"(detection of calcium ion)|go:"GO:0005813"(centrosome)|go:"GO:0005876"(spindle microtubule)|go:"GO:0010880"(regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum)|go:"GO:0021762"(substantia nigra development)|go:"GO:0030017"(sarcomere)|go:"GO:0032465"(regulation of cytokinesis)|go:"GO:0032516"(positive regulation of phosphoprotein phosphatase activity)|go:"GO:0034704"(calcium channel complex)|go:"GO:0051343"(positive regulation of cyclic-nucleotide phosphodiesterase activity)|go:"GO:0055117"(regulation of cardiac muscle contraction)|go:"GO:0060316"(positive regulation of ryanodine-sensitive calcium-release channel activity)|go:"GO:0070062"(extracellular exosome)|go:"GO:0072542"(protein phosphatase activator activity)|go:"GO:0014069"(postsynaptic density)|go:"GO:0099566"(regulation of postsynaptic cytosolic calcium ion concentration)|reactome:R-RNO-8876725|go:"GO:0001975"(response to amphetamine)|go:"GO:0051412"(response to corticosterone)|rcsb pdb:4EHQ|rcsb pdb:4J9Y|rcsb pdb:4J9Z|reactome:R-RNO-163615|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030234"(enzyme regulator activity)|go:"GO:0031800"(type 3 metabotropic glutamate receptor binding)|go:"GO:0043005"(neuron projection)|go:"GO:0043548"(phosphatidylinositol 3-kinase binding)|go:"GO:0048306"(calcium-dependent protein binding)|rcsb pdb:2MGU|ensembl:ENSRNOT00000022603|ensembl:ENSRNOT00000064679|rcsb pdb:3WLC|rcsb pdb:3WLD|reactome:R-RNO-111932|reactome:R-RNO-111933|reactome:R-RNO-111957|reactome:R-RNO-114608|reactome:R-RNO-1474151|reactome:R-RNO-1855204|reactome:R-RNO-203615|reactome:R-RNO-2514859|reactome:R-RNO-2871809|reactome:R-RNO-4086398|reactome:R-RNO-442717|reactome:R-RNO-442729|reactome:R-RNO-442745|reactome:R-RNO-442982|reactome:R-RNO-445355|reactome:R-RNO-451308|reactome:R-RNO-5218920|reactome:R-RNO-5607763|reactome:R-RNO-5626467|reactome:R-RNO-5627123|reactome:R-RNO-5673001|reactome:R-RNO-70221|ensembl:ENSRNOG00000004060|ensembl:ENSRNOG00000016770|ensembl:ENSRNOP00000022603|ensembl:ENSRNOP00000063822|go:"GO:0008076"(voltage-gated potassium channel complex)|go:"GO:0000086"(G2/M transition of mitotic cell cycle)|go:"GO:0043388"(positive regulation of DNA binding)|go:"GO:0019855"(calcium channel inhibitor activity)|go:"GO:0060315"(negative regulation of ryanodine-sensitive calcium-release channel activity)	-	-	-	figure legend:st1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10116(rat-hippocampus)|taxid:10116(Rattus norvegicus hippocampal neurons)	-	2020/10/30	2020/10/30	rogid:DtE+ZXAZKdCMvUW5K+jXQ5bH07M10116	rogid:tTYcOd9bOh211njZVz7cYVybAMQ10116	rigid:zzsc1zNhBb5nwIRPeFpYOKgC3M8	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q5XIE8	uniprotkb:P55068	intact:EBI-15348306|ensembl:ENSRNOP00000023037	intact:EBI-26438001|uniprotkb:Q62860|uniprotkb:Q63040|uniprotkb:Q63513	psi-mi:itm2b_rat(display_long)|uniprotkb:Itm2b(gene name)|psi-mi:Itm2b(display_short)|uniprotkb:Immature BRI2(gene name synonym)|uniprotkb:Transmembrane protein BRI(gene name synonym)	psi-mi:pgcb_rat(display_long)|uniprotkb:Bcan(gene name)|psi-mi:Bcan(display_short)|uniprotkb:Behab(gene name synonym)|uniprotkb:Brain-enriched hyaluronan-binding protein(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Martins et al. (2018)	imex:IM-28469|pubmed:29476059	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26440627|imex:IM-28469-5	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSRNOG00000016271(gene)|ensembl:ENSRNOT00000023037(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001540"(amyloid-beta binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0010008"(endosome membrane)|go:"GO:0030660"(Golgi-associated vesicle membrane)|go:"GO:0031301"(integral component of organelle membrane)|go:"GO:0042985"(negative regulation of amyloid precursor protein biosynthetic process)|interpro:IPR007084(BRICHOS)|interpro:IPR040145|mint:Q5XIE8|refseq:NP_001006964.1|rgd:620727	go:"GO:0001501"(skeletal system development)|go:"GO:0005540"(hyaluronic acid binding)|go:"GO:0005615"(extracellular space)|go:"GO:0007160"(cell-matrix adhesion)|go:"GO:0007417"(central nervous system development)|go:"GO:0007420"(brain development)|go:"GO:0009986"(cell surface)|go:"GO:0021766"(hippocampus development)|go:"GO:0030246"(carbohydrate binding)|go:"GO:0030424"(axon)|go:"GO:0030425"(dendrite)|go:"GO:0031012"(extracellular matrix)|go:"GO:0031225"(anchored component of membrane)|go:"GO:0033268"(node of Ranvier)|go:"GO:0042063"(gliogenesis)|go:"GO:0043194"(axon initial segment)|go:"GO:0045202"(synapse)|go:"GO:0048168"(regulation of neuronal synaptic plasticity)|go:"GO:0060074"(synapse maturation)|go:"GO:0072534"(perineuronal net)|go:"GO:0098966"(perisynaptic extracellular matrix)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0098982"(GABA-ergic synapse)|go:"GO:1990138"(neuron projection extension)|reactome:R-RNO-1474228|reactome:R-RNO-1971475|reactome:R-RNO-2022870|reactome:R-RNO-2022923|reactome:R-RNO-2024101|reactome:R-RNO-3000178|mint:P55068|refseq:NP_001028837.1|refseq:NP_037048.2|interpro:IPR001304(C-type lectin)|interpro:IPR016186(C-type lectin-like)|interpro:IPR018378|interpro:IPR016187(C-type lectin fold)|interpro:IPR000742(EGF-like, type 3)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR036179|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR003006(Immunoglobulin/major histocompatibility complex, conserved site)|interpro:IPR003599(Immunoglobulin subtype)|interpro:IPR013106(Immunoglobulin V-set)|interpro:IPR000538(Link)|interpro:IPR035976|interpro:IPR000436(Sushi/SCR/CCP)|rgd:2194	-	-	-	figure legend:st1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10116(rat-hippocampus)|taxid:10116(Rattus norvegicus hippocampal neurons)	-	2020/10/30	2020/10/30	rogid:DtE+ZXAZKdCMvUW5K+jXQ5bH07M10116	rogid:lF9PzbTBUsVJ4tGND2U0A/3v3aY10116	rigid:zzsc1zNhBb5nwIRPeFpYOKgC3M8	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q5XIE8	uniprotkb:Q6PDU7	intact:EBI-15348306|ensembl:ENSRNOP00000023037	intact:EBI-2255888|uniprotkb:G3V9A9|ensembl:ENSRNOP00000040969	psi-mi:itm2b_rat(display_long)|uniprotkb:Itm2b(gene name)|psi-mi:Itm2b(display_short)|uniprotkb:Immature BRI2(gene name synonym)|uniprotkb:Transmembrane protein BRI(gene name synonym)	psi-mi:atp5l_rat(display_long)|uniprotkb:Atp5mg(gene name)|psi-mi:Atp5mg(display_short)|uniprotkb:ATP synthase membrane subunit g(gene name synonym)|uniprotkb:Atp5l(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Martins et al. (2018)	imex:IM-28469|pubmed:29476059	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26440627|imex:IM-28469-5	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSRNOG00000016271(gene)|ensembl:ENSRNOT00000023037(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001540"(amyloid-beta binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0010008"(endosome membrane)|go:"GO:0030660"(Golgi-associated vesicle membrane)|go:"GO:0031301"(integral component of organelle membrane)|go:"GO:0042985"(negative regulation of amyloid precursor protein biosynthetic process)|interpro:IPR007084(BRICHOS)|interpro:IPR040145|mint:Q5XIE8|refseq:NP_001006964.1|rgd:620727	rgd:1303259|refseq:NP_997681.1|ensembl:ENSRNOG00000028884(gene)|ensembl:ENSRNOT00000050878(transcript)|go:"GO:0000276"("mitochondrial proton-transporting ATP synthase complex, coupling factor F(o)")|go:"GO:0005753"(mitochondrial proton-transporting ATP synthase complex)|go:"GO:0015078"(proton transmembrane transporter activity)|go:"GO:0015986"(ATP synthesis coupled proton transport)|go:"GO:0042776"(mitochondrial ATP synthesis coupled proton transport)|go:"GO:0046034"(ATP metabolic process)|interpro:IPR006808(ATPase, F0 complex, subunit G, mitochondrial)|interpro:IPR016702(Mitochondrial ATP synthase subunit g, animal)|mint:Q6PDU7|reactome:R-RNO-163210|reactome:R-RNO-8949613	-	-	-	figure legend:st1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10116(rat-hippocampus)|taxid:10116(Rattus norvegicus hippocampal neurons)	-	2020/10/30	2020/10/30	rogid:DtE+ZXAZKdCMvUW5K+jXQ5bH07M10116	rogid:z3KVnfCKanB5KSzgEuxsY4pAlds10116	rigid:zzsc1zNhBb5nwIRPeFpYOKgC3M8	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q5XIE8	uniprotkb:D3ZAF6	intact:EBI-15348306|ensembl:ENSRNOP00000023037	intact:EBI-26437983|ensembl:ENSRNOP00000029426	psi-mi:itm2b_rat(display_long)|uniprotkb:Itm2b(gene name)|psi-mi:Itm2b(display_short)|uniprotkb:Immature BRI2(gene name synonym)|uniprotkb:Transmembrane protein BRI(gene name synonym)	psi-mi:atpk_rat(display_long)|uniprotkb:Atp5mf(gene name)|psi-mi:Atp5mf(display_short)|uniprotkb:Atp5j2(gene name synonym)|uniprotkb:ATP synthase membrane subunit f(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Martins et al. (2018)	imex:IM-28469|pubmed:29476059	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26440627|imex:IM-28469-5	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSRNOG00000016271(gene)|ensembl:ENSRNOT00000023037(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001540"(amyloid-beta binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0010008"(endosome membrane)|go:"GO:0030660"(Golgi-associated vesicle membrane)|go:"GO:0031301"(integral component of organelle membrane)|go:"GO:0042985"(negative regulation of amyloid precursor protein biosynthetic process)|interpro:IPR007084(BRICHOS)|interpro:IPR040145|mint:Q5XIE8|refseq:NP_001006964.1|rgd:620727	ensembl:ENSRNOG00000027049(gene)|ensembl:ENSRNOT00000033537(transcript)|go:"GO:0000276"("mitochondrial proton-transporting ATP synthase complex, coupling factor F(o)")|go:"GO:0005753"(mitochondrial proton-transporting ATP synthase complex)|go:"GO:0016021"(integral component of membrane)|go:"GO:0031965"(nuclear membrane)|go:"GO:0042776"(mitochondrial ATP synthesis coupled proton transport)|go:"GO:0046034"(ATP metabolic process)|go:"GO:0046933"(proton-transporting ATP synthase activity, rotational mechanism)|interpro:IPR019344|mint:D3ZAF6|reactome:R-RNO-163210|reactome:R-RNO-8949613|refseq:NP_001258046.1|rgd:1596067	-	-	-	figure legend:st1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10116(rat-hippocampus)|taxid:10116(Rattus norvegicus hippocampal neurons)	-	2020/10/30	2020/10/30	rogid:DtE+ZXAZKdCMvUW5K+jXQ5bH07M10116	rogid:vcwbNZR75EcqIXL/9z6Qw/Fyml810116	rigid:zzsc1zNhBb5nwIRPeFpYOKgC3M8	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q5XIE8	uniprotkb:P54921	intact:EBI-15348306|ensembl:ENSRNOP00000023037	intact:EBI-917790|ensembl:ENSRNOP00000002044	psi-mi:itm2b_rat(display_long)|uniprotkb:Itm2b(gene name)|psi-mi:Itm2b(display_short)|uniprotkb:Immature BRI2(gene name synonym)|uniprotkb:Transmembrane protein BRI(gene name synonym)	psi-mi:snaa_rat(display_long)|uniprotkb:N-ethylmaleimide-sensitive factor attachment protein alpha(gene name synonym)|uniprotkb:Napa(gene name)|psi-mi:Napa(display_short)|uniprotkb:Snap(gene name synonym)|uniprotkb:Snapa(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Martins et al. (2018)	imex:IM-28469|pubmed:29476059	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26440627|imex:IM-28469-5	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSRNOG00000016271(gene)|ensembl:ENSRNOT00000023037(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001540"(amyloid-beta binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0010008"(endosome membrane)|go:"GO:0030660"(Golgi-associated vesicle membrane)|go:"GO:0031301"(integral component of organelle membrane)|go:"GO:0042985"(negative regulation of amyloid precursor protein biosynthetic process)|interpro:IPR007084(BRICHOS)|interpro:IPR040145|mint:Q5XIE8|refseq:NP_001006964.1|rgd:620727	rgd:620855|refseq:NP_542152.1|dip:DIP-37030N|ensembl:ENSRNOG00000001494(gene)|ensembl:ENSRNOT00000002044(transcript)|go:"GO:0000149"(SNARE binding)|go:"GO:0005483"(soluble NSF attachment protein activity)|go:"GO:0005774"(vacuolar membrane)|go:"GO:0005886"(plasma membrane)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0007420"(brain development)|go:"GO:0010807"(regulation of synaptic vesicle priming)|go:"GO:0016082"(synaptic vesicle priming)|go:"GO:0019905"(syntaxin binding)|go:"GO:0030182"(neuron differentiation)|go:"GO:0031201"(SNARE complex)|go:"GO:0032781"(positive regulation of ATP-dependent activity)|go:"GO:0032984"(protein-containing complex disassembly)|go:"GO:0035249"(synaptic transmission, glutamatergic)|go:"GO:0035494"(SNARE complex disassembly)|go:"GO:0043195"(terminal bouton)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045176"(apical protein localization)|go:"GO:0061025"(membrane fusion)|go:"GO:0070044"(synaptobrevin 2-SNAP-25-syntaxin-1a complex)|go:"GO:0098793"(presynapse)|go:"GO:0098794"(postsynapse)|go:"GO:0098978"(glutamatergic synapse)|interpro:IPR000744(NSF attachment protein)|interpro:IPR011990(Tetratricopeptide-like helical)|mint:P54921|rcsb pdb:3J96|rcsb pdb:3J97|rcsb pdb:3J98|rcsb pdb:3J99|rcsb pdb:6MDM|rcsb pdb:6MDN|reactome:R-RNO-204005|reactome:R-RNO-432722|reactome:R-RNO-6807878|reactome:R-RNO-6811434|reactome:R-RNO-6811438|reactome:R-RNO-6811440	-	-	-	figure legend:st1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10116(rat-hippocampus)|taxid:10116(Rattus norvegicus hippocampal neurons)	-	2020/10/30	2020/10/30	rogid:DtE+ZXAZKdCMvUW5K+jXQ5bH07M10116	rogid:+Lm6fLpvZFjClv3xfc066b0H2Gc10116	rigid:zzsc1zNhBb5nwIRPeFpYOKgC3M8	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q5XIE8	uniprotkb:Q63028	intact:EBI-15348306|ensembl:ENSRNOP00000023037	intact:EBI-26437931|uniprotkb:Q3B7D4|uniprotkb:Q64722	psi-mi:itm2b_rat(display_long)|uniprotkb:Itm2b(gene name)|psi-mi:Itm2b(display_short)|uniprotkb:Immature BRI2(gene name synonym)|uniprotkb:Transmembrane protein BRI(gene name synonym)	psi-mi:adda_rat(display_long)|uniprotkb:Add1(gene name)|psi-mi:Add1(display_short)|uniprotkb:Erythrocyte adducin subunit alpha(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Martins et al. (2018)	imex:IM-28469|pubmed:29476059	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26440627|imex:IM-28469-5	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSRNOG00000016271(gene)|ensembl:ENSRNOT00000023037(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001540"(amyloid-beta binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0010008"(endosome membrane)|go:"GO:0030660"(Golgi-associated vesicle membrane)|go:"GO:0031301"(integral component of organelle membrane)|go:"GO:0042985"(negative regulation of amyloid precursor protein biosynthetic process)|interpro:IPR007084(BRICHOS)|interpro:IPR040145|mint:Q5XIE8|refseq:NP_001006964.1|rgd:620727	go:"GO:0000902"(cell morphogenesis)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0005200"(structural constituent of cytoskeleton)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005886"(plasma membrane)|go:"GO:0005912"(adherens junction)|go:"GO:0006811"(ion transport)|go:"GO:0006884"(cell volume homeostasis)|go:"GO:0007010"(cytoskeleton organization)|go:"GO:0008290"(F-actin capping protein complex)|go:"GO:0014069"(postsynaptic density)|go:"GO:0016020"(membrane)|go:"GO:0020027"(hemoglobin metabolic process)|go:"GO:0030218"(erythrocyte differentiation)|go:"GO:0030425"(dendrite)|go:"GO:0030507"(spectrin binding)|go:"GO:0030837"(negative regulation of actin filament polymerization)|go:"GO:0032092"(positive regulation of protein binding)|go:"GO:0035264"(multicellular organism growth)|go:"GO:0042608"(T cell receptor binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043197"(dendritic spine)|go:"GO:0045202"(synapse)|go:"GO:0045766"(positive regulation of angiogenesis)|go:"GO:0045807"(positive regulation of endocytosis)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0048873"(homeostasis of number of cells within a tissue)|go:"GO:0051015"(actin filament binding)|go:"GO:0051016"(barbed-end actin filament capping)|go:"GO:0051017"(actin filament bundle assembly)|go:"GO:0071277"(cellular response to calcium ion)|go:"GO:0071300"(cellular response to retinoic acid)|go:"GO:1903142"(positive regulation of establishment of endothelial barrier)|go:"GO:1903393"(positive regulation of adherens junction organization)|reactome:R-RNO-264870|reactome:R-RNO-5223345|mint:Q63028|refseq:NP_058686.2|interpro:IPR027766|interpro:IPR001303(Class II aldolase/adducin, N-terminal)|interpro:IPR036409|rgd:2041	-	-	-	figure legend:st1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10116(rat-hippocampus)|taxid:10116(Rattus norvegicus hippocampal neurons)	-	2020/10/30	2020/10/30	rogid:DtE+ZXAZKdCMvUW5K+jXQ5bH07M10116	rogid:T27XZNiVX2+OqOG0UuPsYWGSUT810116	rigid:zzsc1zNhBb5nwIRPeFpYOKgC3M8	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q5XIE8	uniprotkb:Q9Z270	intact:EBI-15348306|ensembl:ENSRNOP00000023037	intact:EBI-2909425|ensembl:ENSRNOP00000020681|uniprotkb:Q6P723	psi-mi:itm2b_rat(display_long)|uniprotkb:Itm2b(gene name)|psi-mi:Itm2b(display_short)|uniprotkb:Immature BRI2(gene name synonym)|uniprotkb:Transmembrane protein BRI(gene name synonym)	psi-mi:vapa_rat(display_long)|uniprotkb:Vapa(gene name)|psi-mi:Vapa(display_short)|uniprotkb:Vap33(gene name synonym)|uniprotkb:33 kDa VAMP-associated protein(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Martins et al. (2018)	imex:IM-28469|pubmed:29476059	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26440627|imex:IM-28469-5	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSRNOG00000016271(gene)|ensembl:ENSRNOT00000023037(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001540"(amyloid-beta binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0010008"(endosome membrane)|go:"GO:0030660"(Golgi-associated vesicle membrane)|go:"GO:0031301"(integral component of organelle membrane)|go:"GO:0042985"(negative regulation of amyloid precursor protein biosynthetic process)|interpro:IPR007084(BRICHOS)|interpro:IPR040145|mint:Q5XIE8|refseq:NP_001006964.1|rgd:620727	ensembl:ENSRNOG00000014765(gene)|ensembl:ENSRNOT00000020681(transcript)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005886"(plasma membrane)|go:"GO:0005923"(bicellular tight junction)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0008017"(microtubule binding)|go:"GO:0008219"(cell death)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0031175"(neuron projection development)|go:"GO:0031965"(nuclear membrane)|go:"GO:0031982"(vesicle)|go:"GO:0033149"(FFAT motif binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0044791"(obsolete positive regulation by host of viral release from host cell)|go:"GO:0044828"(negative regulation by host of viral genome replication)|go:"GO:0044829"(positive regulation by host of viral genome replication)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0070972"(protein localization to endoplasmic reticulum)|go:"GO:0090114"(COPII-coated vesicle budding)|interpro:IPR000535(Major sperm protein)|interpro:IPR008962(PapD-like)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR016763(Vesicle-associated membrane protein)|mint:Q9Z270|rcsb pdb:1Z9L|rcsb pdb:1Z9O|reactome:R-RNO-1660661|reactome:R-RNO-6798695|reactome:R-RNO-9609523|go:"GO:0046982"(protein heterodimerization activity)|rgd:61803|refseq:NP_113819.3|dip:DIP-48448N	-	-	-	figure legend:st1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10116(rat-hippocampus)|taxid:10116(Rattus norvegicus hippocampal neurons)	-	2020/10/30	2020/10/30	rogid:DtE+ZXAZKdCMvUW5K+jXQ5bH07M10116	rogid:ZMxTb0ZumI4k+ZOZbfLLapSngf810116	rigid:zzsc1zNhBb5nwIRPeFpYOKgC3M8	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q5XIE8	uniprotkb:P19234	intact:EBI-15348306|ensembl:ENSRNOP00000023037	intact:EBI-916768|uniprotkb:Q6PDU9|ensembl:ENSRNOP00000016965	psi-mi:itm2b_rat(display_long)|uniprotkb:Itm2b(gene name)|psi-mi:Itm2b(display_short)|uniprotkb:Immature BRI2(gene name synonym)|uniprotkb:Transmembrane protein BRI(gene name synonym)	psi-mi:nduv2_rat(display_long)|uniprotkb:NADH-ubiquinone oxidoreductase 24 kDa subunit(gene name synonym)|uniprotkb:Ndufv2(gene name)|psi-mi:Ndufv2(display_short)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Martins et al. (2018)	imex:IM-28469|pubmed:29476059	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26440627|imex:IM-28469-5	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSRNOG00000016271(gene)|ensembl:ENSRNOT00000023037(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001540"(amyloid-beta binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0010008"(endosome membrane)|go:"GO:0030660"(Golgi-associated vesicle membrane)|go:"GO:0031301"(integral component of organelle membrane)|go:"GO:0042985"(negative regulation of amyloid precursor protein biosynthetic process)|interpro:IPR007084(BRICHOS)|interpro:IPR040145|mint:Q5XIE8|refseq:NP_001006964.1|rgd:620727	rgd:621733|refseq:NP_112326.1|ensembl:ENSRNOG00000042503(gene)|ensembl:ENSRNOT00000016965(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005747"(mitochondrial respiratory chain complex I)|go:"GO:0005829"(cytosol)|go:"GO:0006120"(mitochondrial electron transport, NADH to ubiquinone)|go:"GO:0007399"(nervous system development)|go:"GO:0008137"("NADH dehydrogenase (ubiquinone) activity")|go:"GO:0046872"(metal ion binding)|go:"GO:0048738"(cardiac muscle tissue development)|go:"GO:0051537"(2 iron, 2 sulfur cluster binding)|interpro:IPR002023("NADH dehydrogenase (ubiquinone), 24 kDa subunit")|interpro:IPR036249|interpro:IPR041921|interpro:IPR042128|mint:P19234|reactome:R-RNO-611105|reactome:R-RNO-6799198	-	-	-	figure legend:st1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10116(rat-hippocampus)|taxid:10116(Rattus norvegicus hippocampal neurons)	-	2020/10/30	2020/10/30	rogid:DtE+ZXAZKdCMvUW5K+jXQ5bH07M10116	rogid:DJh8LBV775oK8nsimzcy05KUBRg10116	rigid:zzsc1zNhBb5nwIRPeFpYOKgC3M8	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q5XIE8	uniprotkb:Q01986	intact:EBI-15348306|ensembl:ENSRNOP00000023037	intact:EBI-26373480|uniprotkb:Q5EBD5	psi-mi:itm2b_rat(display_long)|uniprotkb:Itm2b(gene name)|psi-mi:Itm2b(display_short)|uniprotkb:Immature BRI2(gene name synonym)|uniprotkb:Transmembrane protein BRI(gene name synonym)	psi-mi:mp2k1_rat(display_long)|uniprotkb:ERK activator kinase 1(gene name synonym)|uniprotkb:MAPK/ERK kinase 1(gene name synonym)|uniprotkb:Map2k1(gene name)|psi-mi:Map2k1(display_short)|uniprotkb:Mek1(gene name synonym)|uniprotkb:Prkmk1(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Martins et al. (2018)	imex:IM-28469|pubmed:29476059	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26440627|imex:IM-28469-5	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSRNOG00000016271(gene)|ensembl:ENSRNOT00000023037(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001540"(amyloid-beta binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0010008"(endosome membrane)|go:"GO:0030660"(Golgi-associated vesicle membrane)|go:"GO:0031301"(integral component of organelle membrane)|go:"GO:0042985"(negative regulation of amyloid precursor protein biosynthetic process)|interpro:IPR007084(BRICHOS)|interpro:IPR040145|mint:Q5XIE8|refseq:NP_001006964.1|rgd:620727	go:"GO:0060502"(epithelial cell proliferation involved in lung morphogenesis)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0060674"(placenta blood vessel development)|go:"GO:0060711"(labyrinthine layer development)|go:"GO:0070328"(triglyceride homeostasis)|go:"GO:0070371"(ERK1 and ERK2 cascade)|go:"GO:0070372"(regulation of ERK1 and ERK2 cascade)|go:"GO:0070374"(positive regulation of ERK1 and ERK2 cascade)|go:"GO:0106311"|go:"GO:1903298"(negative regulation of hypoxia-induced intrinsic apoptotic signaling pathway)|go:"GO:1903800"(positive regulation of production of miRNAs involved in gene silencing by miRNA)|go:"GO:2000641"(regulation of early endosome to late endosome transport)|go:"GO:0071902"(positive regulation of protein serine/threonine kinase activity)|go:"GO:0090170"(regulation of Golgi inheritance)|go:"GO:2001171"(positive regulation of ATP biosynthetic process)|go:"GO:0090398"(cellular senescence)|go:"GO:0097110"(scaffold protein binding)|go:"GO:0098696"(regulation of neurotransmitter receptor localization to postsynaptic specialization membrane)|reactome:R-RNO-110056|reactome:R-RNO-170968|reactome:R-RNO-445144|reactome:R-RNO-5673000|reactome:R-RNO-5674135|reactome:R-RNO-5674499|go:"GO:0000187"(obsolete activation of MAPK activity)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0003056"(regulation of vascular associated smooth muscle contraction)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0004708"(MAP kinase kinase activity)|go:"GO:0004712"(protein serine/threonine/tyrosine kinase activity)|go:"GO:0004714"(transmembrane receptor protein tyrosine kinase activity)|go:"GO:0005078"(MAP-kinase scaffold activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005739"(mitochondrion)|go:"GO:0005769"(early endosome)|go:"GO:0005770"(late endosome)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005815"(microtubule organizing center)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005925"(focal adhesion)|go:"GO:0005938"(cell cortex)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0006979"(response to oxidative stress)|go:"GO:0007507"(heart development)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008283"(cell population proliferation)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0010508"(positive regulation of autophagy)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0014069"(postsynaptic density)|go:"GO:0018107"(peptidyl-threonine phosphorylation)|go:"GO:0019901"(protein kinase binding)|go:"GO:0021697"(cerebellar cortex formation)|go:"GO:0030182"(neuron differentiation)|go:"GO:0030216"(keratinocyte differentiation)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0030424"(axon)|go:"GO:0030425"(dendrite)|go:"GO:0030878"(thyroid gland development)|go:"GO:0031267"(small GTPase binding)|go:"GO:0031435"(mitogen-activated protein kinase kinase kinase binding)|go:"GO:0032402"(melanosome transport)|go:"GO:0032839"(dendrite cytoplasm)|go:"GO:0032872"(regulation of stress-activated MAPK cascade)|go:"GO:0032968"(positive regulation of transcription elongation from RNA polymerase II promoter)|go:"GO:0034111"(negative regulation of homotypic cell-cell adhesion)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0042593"(glucose homeostasis)|go:"GO:0043204"(perikaryon)|go:"GO:0043539"(protein serine/threonine kinase activator activity)|go:"GO:0043547"(positive regulation of GTPase activity)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045597"(positive regulation of cell differentiation)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045933"(positive regulation of muscle contraction)|go:"GO:0046579"(positive regulation of Ras protein signal transduction)|go:"GO:0047485"(protein N-terminus binding)|go:"GO:0047496"(vesicle transport along microtubule)|go:"GO:0048313"(Golgi inheritance)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0048538"(thymus development)|go:"GO:0048678"(response to axon injury)|go:"GO:0048679"(regulation of axon regeneration)|go:"GO:0048812"(neuron projection morphogenesis)|go:"GO:0048870"(cell motility)|go:"GO:0050772"(positive regulation of axonogenesis)|go:"GO:0051384"(response to glucocorticoid)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0060020"(Bergmann glial cell differentiation)|go:"GO:0060324"(face development)|go:"GO:0060425"(lung morphogenesis)|go:"GO:0060440"(trachea formation)|rgd:70495|mint:Q01986|refseq:NP_113831.1|interpro:IPR011009(Protein kinase-like)|interpro:IPR000719(Protein kinase, core)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR008271(Serine/threonine protein kinase, active site)	-	-	-	figure legend:st1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10116(rat-hippocampus)|taxid:10116(Rattus norvegicus hippocampal neurons)	-	2020/10/30	2020/10/30	rogid:DtE+ZXAZKdCMvUW5K+jXQ5bH07M10116	rogid:XblxWneV7tc/8bwEVlk103FIRCg10116	rigid:zzsc1zNhBb5nwIRPeFpYOKgC3M8	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q5XIE8	uniprotkb:Q561S0	intact:EBI-15348306|ensembl:ENSRNOP00000023037	intact:EBI-22250632|ensembl:ENSRNOP00000022089|uniprotkb:Q80WE0	psi-mi:itm2b_rat(display_long)|uniprotkb:Itm2b(gene name)|psi-mi:Itm2b(display_short)|uniprotkb:Immature BRI2(gene name synonym)|uniprotkb:Transmembrane protein BRI(gene name synonym)	psi-mi:nduaa_rat(display_long)|uniprotkb:Complex I-42kD(gene name synonym)|uniprotkb:NADH-ubiquinone oxidoreductase 42 kDa subunit(gene name synonym)|uniprotkb:Ndufa10(gene name)|psi-mi:Ndufa10(display_short)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Martins et al. (2018)	imex:IM-28469|pubmed:29476059	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26440627|imex:IM-28469-5	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSRNOG00000016271(gene)|ensembl:ENSRNOT00000023037(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001540"(amyloid-beta binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0010008"(endosome membrane)|go:"GO:0030660"(Golgi-associated vesicle membrane)|go:"GO:0031301"(integral component of organelle membrane)|go:"GO:0042985"(negative regulation of amyloid precursor protein biosynthetic process)|interpro:IPR007084(BRICHOS)|interpro:IPR040145|mint:Q5XIE8|refseq:NP_001006964.1|rgd:620727	ensembl:ENSRNOG00000016470(gene)|ensembl:ENSRNOT00000022089(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0005747"(mitochondrial respiratory chain complex I)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0006120"(mitochondrial electron transport, NADH to ubiquinone)|go:"GO:0008137"("NADH dehydrogenase (ubiquinone) activity")|go:"GO:0032981"(mitochondrial respiratory chain complex I assembly)|go:"GO:0042493"|interpro:IPR015828(NADH-ubiquinone oxidoreductase, 42 kDa subunit)|interpro:IPR027417|interpro:IPR031314|reactome:R-RNO-611105|reactome:R-RNO-6799198|mint:Q561S0|refseq:NP_872612.1|refseq:NP_955789.2|rgd:727968	-	-	-	figure legend:st1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10116(rat-hippocampus)|taxid:10116(Rattus norvegicus hippocampal neurons)	-	2020/10/30	2020/10/30	rogid:DtE+ZXAZKdCMvUW5K+jXQ5bH07M10116	rogid:WdH5x1mQ7WuKYu6aBc3neTbxYOY10116	rigid:zzsc1zNhBb5nwIRPeFpYOKgC3M8	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q5XIE8	uniprotkb:Q641Y2	intact:EBI-15348306|ensembl:ENSRNOP00000023037	intact:EBI-2255868|ensembl:ENSRNOP00000055224	psi-mi:itm2b_rat(display_long)|uniprotkb:Itm2b(gene name)|psi-mi:Itm2b(display_short)|uniprotkb:Immature BRI2(gene name synonym)|uniprotkb:Transmembrane protein BRI(gene name synonym)	psi-mi:ndus2_rat(display_long)|uniprotkb:Ndufs2(gene name)|psi-mi:Ndufs2(display_short)|uniprotkb:NADH-ubiquinone oxidoreductase 49 kDa subunit(gene name synonym)|uniprotkb:Complex I-49kD(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Martins et al. (2018)	imex:IM-28469|pubmed:29476059	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26440627|imex:IM-28469-5	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSRNOG00000016271(gene)|ensembl:ENSRNOT00000023037(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001540"(amyloid-beta binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0010008"(endosome membrane)|go:"GO:0030660"(Golgi-associated vesicle membrane)|go:"GO:0031301"(integral component of organelle membrane)|go:"GO:0042985"(negative regulation of amyloid precursor protein biosynthetic process)|interpro:IPR007084(BRICHOS)|interpro:IPR040145|mint:Q5XIE8|refseq:NP_001006964.1|rgd:620727	rgd:1307109|refseq:NP_001011907.1|refseq:XP_003751325.1|ensembl:ENSRNOG00000038372(gene)|ensembl:ENSRNOT00000058423(transcript)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005747"(mitochondrial respiratory chain complex I)|go:"GO:0006120"(mitochondrial electron transport, NADH to ubiquinone)|go:"GO:0006979"(response to oxidative stress)|go:"GO:0008137"("NADH dehydrogenase (ubiquinone) activity")|go:"GO:0019826"(oxygen sensor activity)|go:"GO:0022008"(neurogenesis)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032981"(mitochondrial respiratory chain complex I assembly)|go:"GO:0042063"(gliogenesis)|go:"GO:0042775"(mitochondrial ATP synthesis coupled electron transport)|go:"GO:0046872"(metal ion binding)|go:"GO:0048038"(quinone binding)|go:"GO:0051287"(NAD binding)|go:"GO:0051539"(4 iron, 4 sulfur cluster binding)|go:"GO:0061351"(neural precursor cell proliferation)|go:"GO:0071453"(cellular response to oxygen levels)|interpro:IPR001135(NADH-ubiquinone oxidoreductase, chain 49kDa)|interpro:IPR014029(NADH-ubiquinone oxidoreductase, chain 49kDa, conserved site)|interpro:IPR022885|interpro:IPR029014|mint:Q641Y2|reactome:R-RNO-611105|reactome:R-RNO-6799198	-	-	-	figure legend:st1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10116(rat-hippocampus)|taxid:10116(Rattus norvegicus hippocampal neurons)	-	2020/10/30	2020/10/30	rogid:DtE+ZXAZKdCMvUW5K+jXQ5bH07M10116	rogid:qI/W2Xwbd6EAVs+DpyXO5YsnPK410116	rigid:zzsc1zNhBb5nwIRPeFpYOKgC3M8	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q5XIE8	uniprotkb:O35353	intact:EBI-15348306|ensembl:ENSRNOP00000023037	intact:EBI-1374407|uniprotkb:Q4V8I8|uniprotkb:Q6Q8B2	psi-mi:itm2b_rat(display_long)|uniprotkb:Itm2b(gene name)|psi-mi:Itm2b(display_short)|uniprotkb:Immature BRI2(gene name synonym)|uniprotkb:Transmembrane protein BRI(gene name synonym)	psi-mi:gbb4_rat(display_long)|uniprotkb:Gnb4(gene name)|psi-mi:Gnb4(display_short)|uniprotkb:Transducin beta chain 4(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Martins et al. (2018)	imex:IM-28469|pubmed:29476059	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26440627|imex:IM-28469-5	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSRNOG00000016271(gene)|ensembl:ENSRNOT00000023037(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001540"(amyloid-beta binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0010008"(endosome membrane)|go:"GO:0030660"(Golgi-associated vesicle membrane)|go:"GO:0031301"(integral component of organelle membrane)|go:"GO:0042985"(negative regulation of amyloid precursor protein biosynthetic process)|interpro:IPR007084(BRICHOS)|interpro:IPR040145|mint:Q5XIE8|refseq:NP_001006964.1|rgd:620727	rgd:1359321|refseq:NP_001013932.1|interpro:IPR020472|interpro:IPR001632(G-protein, beta subunit)|interpro:IPR016346(Guanine nucleotide-binding protein, beta subunit)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR001680(WD40 repeat)|interpro:IPR019775|interpro:IPR036322|go:"GO:0005737"(cytoplasm)|go:"GO:0005834"(heterotrimeric G-protein complex)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0031682"(G-protein gamma-subunit binding)|go:"GO:0044297"(cell body)|go:"GO:0044877"(protein-containing complex binding)|reactome:R-RNO-1296041|reactome:R-RNO-202040|reactome:R-RNO-381676|reactome:R-RNO-392170|reactome:R-RNO-392451|reactome:R-RNO-400042|reactome:R-RNO-4086398|reactome:R-RNO-416476|reactome:R-RNO-418594|reactome:R-RNO-418597|reactome:R-RNO-420092|reactome:R-RNO-428930|reactome:R-RNO-432040|reactome:R-RNO-456926|reactome:R-RNO-6814122|reactome:R-RNO-8964616|reactome:R-RNO-997272|mint:O35353	-	-	-	figure legend:st1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10116(rat-hippocampus)|taxid:10116(Rattus norvegicus hippocampal neurons)	-	2020/10/30	2020/10/30	rogid:DtE+ZXAZKdCMvUW5K+jXQ5bH07M10116	rogid:At4d9m6HkQf6Uy/oMrC2/MR+5fg10116	rigid:zzsc1zNhBb5nwIRPeFpYOKgC3M8	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q5XIE8	uniprotkb:Q9JI66	intact:EBI-15348306|ensembl:ENSRNOP00000023037	intact:EBI-15349394|ensembl:ENSRNOP00000035006|uniprotkb:O35422|uniprotkb:O54815|uniprotkb:Q9JJ32|uniprotkb:Q9QXH6	psi-mi:itm2b_rat(display_long)|uniprotkb:Itm2b(gene name)|psi-mi:Itm2b(display_short)|uniprotkb:Immature BRI2(gene name synonym)|uniprotkb:Transmembrane protein BRI(gene name synonym)	psi-mi:s4a4_rat(display_long)|uniprotkb:Slc4a4(gene name)|psi-mi:Slc4a4(display_short)|uniprotkb:Nbc(gene name synonym)|uniprotkb:Nbc1(gene name synonym)|uniprotkb:Nbce1(gene name synonym)|uniprotkb:Rnbc1(gene name synonym)|uniprotkb:NBC-like protein(gene name synonym)|uniprotkb:"Na(+)/HCO3(-) cotransporter"(gene name synonym)|uniprotkb:Solute carrier family 4 member 4(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Martins et al. (2018)	imex:IM-28469|pubmed:29476059	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26440627|imex:IM-28469-5	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSRNOG00000016271(gene)|ensembl:ENSRNOT00000023037(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001540"(amyloid-beta binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0010008"(endosome membrane)|go:"GO:0030660"(Golgi-associated vesicle membrane)|go:"GO:0031301"(integral component of organelle membrane)|go:"GO:0042985"(negative regulation of amyloid precursor protein biosynthetic process)|interpro:IPR007084(BRICHOS)|interpro:IPR040145|mint:Q5XIE8|refseq:NP_001006964.1|rgd:620727	ensembl:ENSRNOG00000003134(gene)|ensembl:ENSRNOT00000033806(transcript)|go:"GO:0005452"(inorganic anion exchanger activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006814"(sodium ion transport)|go:"GO:0006885"(regulation of pH)|go:"GO:0008510"("sodium:bicarbonate symporter activity")|go:"GO:0009986"(cell surface)|go:"GO:0015293"(symporter activity)|go:"GO:0016020"(membrane)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0022857"(transmembrane transporter activity)|go:"GO:0035725"(sodium ion transmembrane transport)|go:"GO:0036376"(sodium ion export across plasma membrane)|go:"GO:0042391"(regulation of membrane potential)|go:"GO:0042802"(identical protein binding)|go:"GO:0045821"(positive regulation of glycolytic process)|go:"GO:0050801"(ion homeostasis)|go:"GO:0051453"(regulation of intracellular pH)|go:"GO:0055085"(transmembrane transport)|interpro:IPR003020(Bicarbonate transporter, eukaryotic)|interpro:IPR003024(Sodium bicarbonate cotransporter)|interpro:IPR011531(Bicarbonate transporter, C-terminal)|interpro:IPR013769(Bicarbonate transporter, cytoplasmic)|go:"GO:0015701"(bicarbonate transport)|mint:Q9JI66|reactome:R-RNO-425381|interpro:IPR016152(Phosphotransferase/anion transporter)|rgd:68936|refseq:NP_445876.1|refseq:XP_006250853.1	-	-	-	figure legend:st1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10116(rat-hippocampus)|taxid:10116(Rattus norvegicus hippocampal neurons)	-	2020/10/30	2020/10/30	rogid:DtE+ZXAZKdCMvUW5K+jXQ5bH07M10116	rogid:BrdKn9iXDlKskSzCLKT7rZ+R3JA10116	rigid:zzsc1zNhBb5nwIRPeFpYOKgC3M8	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q5XIE8	uniprotkb:Q6PCU2	intact:EBI-15348306|ensembl:ENSRNOP00000023037	intact:EBI-919161	psi-mi:itm2b_rat(display_long)|uniprotkb:Itm2b(gene name)|psi-mi:Itm2b(display_short)|uniprotkb:Immature BRI2(gene name synonym)|uniprotkb:Transmembrane protein BRI(gene name synonym)	psi-mi:vate1_rat(display_long)|uniprotkb:Atp6v1e1(gene name)|psi-mi:Atp6v1e1(display_short)|uniprotkb:Vacuolar proton pump subunit E 1(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Martins et al. (2018)	imex:IM-28469|pubmed:29476059	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26440627|imex:IM-28469-5	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSRNOG00000016271(gene)|ensembl:ENSRNOT00000023037(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001540"(amyloid-beta binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0010008"(endosome membrane)|go:"GO:0030660"(Golgi-associated vesicle membrane)|go:"GO:0031301"(integral component of organelle membrane)|go:"GO:0042985"(negative regulation of amyloid precursor protein biosynthetic process)|interpro:IPR007084(BRICHOS)|interpro:IPR040145|mint:Q5XIE8|refseq:NP_001006964.1|rgd:620727	rgd:735157|refseq:NP_942040.1|interpro:IPR002842(ATPase, V1/A1 complex, subunit E)|mint:Q6PCU2|interpro:IPR038495|go:"GO:0000221"(vacuolar proton-transporting V-type ATPase, V1 domain)|go:"GO:0005737"(cytoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005829"(cytosol)|go:"GO:0005902"(microvillus)|go:"GO:0008553"(P-type proton-exporting transporter activity)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0016787"(hydrolase activity)|go:"GO:0046961"(proton-transporting ATPase activity, rotational mechanism)|go:"GO:0051117"(ATPase binding)|go:"GO:1902600"(proton transmembrane transport)|rcsb pdb:6VQ6|rcsb pdb:6VQ7|rcsb pdb:6VQ8|rcsb pdb:6VQ9|rcsb pdb:6VQA|rcsb pdb:6VQB|rcsb pdb:6VQI|rcsb pdb:6VQJ|rcsb pdb:6VQK|reactome:R-RNO-1222556|reactome:R-RNO-77387|reactome:R-RNO-917977|reactome:R-RNO-9639288|reactome:R-RNO-983712	-	-	-	figure legend:st1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10116(rat-hippocampus)|taxid:10116(Rattus norvegicus hippocampal neurons)	-	2020/10/30	2020/10/30	rogid:DtE+ZXAZKdCMvUW5K+jXQ5bH07M10116	rogid:mfYO92S6Lf0DGuQmxSaUAoCmQcw10116	rigid:zzsc1zNhBb5nwIRPeFpYOKgC3M8	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q5XIE8	uniprotkb:B2RYG6	intact:EBI-15348306|ensembl:ENSRNOP00000023037	intact:EBI-21995695|ensembl:ENSRNOP00000028752	psi-mi:itm2b_rat(display_long)|uniprotkb:Itm2b(gene name)|psi-mi:Itm2b(display_short)|uniprotkb:Immature BRI2(gene name synonym)|uniprotkb:Transmembrane protein BRI(gene name synonym)	psi-mi:otub1_rat(display_long)|uniprotkb:Deubiquitinating enzyme OTUB1(gene name synonym)|uniprotkb:OTU domain-containing ubiquitin aldehyde-binding protein 1(gene name synonym)|uniprotkb:Otubain-1(gene name synonym)|uniprotkb:Ubiquitin-specific-processing protease OTUB1(gene name synonym)|uniprotkb:Otub1(gene name)|psi-mi:Otub1(display_short)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Martins et al. (2018)	imex:IM-28469|pubmed:29476059	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26440627|imex:IM-28469-5	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSRNOG00000016271(gene)|ensembl:ENSRNOT00000023037(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001540"(amyloid-beta binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0010008"(endosome membrane)|go:"GO:0030660"(Golgi-associated vesicle membrane)|go:"GO:0031301"(integral component of organelle membrane)|go:"GO:0042985"(negative regulation of amyloid precursor protein biosynthetic process)|interpro:IPR007084(BRICHOS)|interpro:IPR040145|mint:Q5XIE8|refseq:NP_001006964.1|rgd:620727	rgd:1311329|refseq:NP_001099802.1|ensembl:ENSRNOG00000021175(gene)|ensembl:ENSRNOT00000028752(transcript)|go:"GO:0002250"(adaptive immune response)|go:"GO:0004843"(thiol-dependent deubiquitinase)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006281"(DNA repair)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0019784"(NEDD8-specific protease activity)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0043130"(ubiquitin binding)|go:"GO:0071108"(protein K48-linked deubiquitination)|go:"GO:0071347"(cellular response to interleukin-1)|go:"GO:1901315"(negative regulation of histone H2A K63-linked ubiquitination)|go:"GO:2000780"(negative regulation of double-strand break repair)|interpro:IPR003323(Ovarian tumour, otubain)|interpro:IPR016615(Ubiquitin thioesterase Otubain)|interpro:IPR019400|interpro:IPR030298|interpro:IPR038765|interpro:IPR042467|interpro:IPR042468|mint:B2RYG6|reactome:R-RNO-5689880|reactome:R-RNO-5689896	-	-	-	figure legend:st1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10116(rat-hippocampus)|taxid:10116(Rattus norvegicus hippocampal neurons)	-	2020/10/30	2020/10/30	rogid:DtE+ZXAZKdCMvUW5K+jXQ5bH07M10116	rogid:8wyAgdbYnbsj8QYkhuruP2tdw5Q10116	rigid:zzsc1zNhBb5nwIRPeFpYOKgC3M8	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q5XIE8	uniprotkb:Q6AYZ1	intact:EBI-15348306|ensembl:ENSRNOP00000023037	intact:EBI-2696581|ensembl:ENSRNOP00000068603	psi-mi:itm2b_rat(display_long)|uniprotkb:Itm2b(gene name)|psi-mi:Itm2b(display_short)|uniprotkb:Immature BRI2(gene name synonym)|uniprotkb:Transmembrane protein BRI(gene name synonym)	psi-mi:tba1c_rat(display_long)|uniprotkb:Tuba1c(gene name)|psi-mi:Tuba1c(display_short)|uniprotkb:Tuba6(gene name synonym)|uniprotkb:Tubulin alpha-6 chain(gene name synonym)|uniprotkb:Alpha-tubulin 6(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Martins et al. (2018)	imex:IM-28469|pubmed:29476059	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26440627|imex:IM-28469-5	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSRNOG00000016271(gene)|ensembl:ENSRNOT00000023037(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001540"(amyloid-beta binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0010008"(endosome membrane)|go:"GO:0030660"(Golgi-associated vesicle membrane)|go:"GO:0031301"(integral component of organelle membrane)|go:"GO:0042985"(negative regulation of amyloid precursor protein biosynthetic process)|interpro:IPR007084(BRICHOS)|interpro:IPR040145|mint:Q5XIE8|refseq:NP_001006964.1|rgd:620727	rgd:1307226|refseq:NP_001011995.1|refseq:XP_003749402.1|ensembl:ENSRNOG00000021438(gene)|ensembl:ENSRNOT00000033450(transcript)|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0005200"(structural constituent of cytoskeleton)|go:"GO:0005525"(GTP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005874"(microtubule)|go:"GO:0005881"(cytoplasmic microtubule)|go:"GO:0045121"(membrane raft)|interpro:IPR000217(Tubulin)|interpro:IPR002452(Alpha tubulin)|interpro:IPR003008(Tubulin/FtsZ, GTPase)|interpro:IPR008280(Tubulin/FtsZ, C-terminal)|interpro:IPR017975|interpro:IPR018316|interpro:IPR023123|interpro:IPR036525|interpro:IPR037103|mint:Q6AYZ1|reactome:R-RNO-190840|reactome:R-RNO-2132295|reactome:R-RNO-2467813|reactome:R-RNO-2500257|reactome:R-RNO-3371497|reactome:R-RNO-380320|reactome:R-RNO-437239|reactome:R-RNO-5610787|reactome:R-RNO-5617833|reactome:R-RNO-5620924|reactome:R-RNO-5626467|reactome:R-RNO-5663220|reactome:R-RNO-6807878|reactome:R-RNO-6811434|reactome:R-RNO-6811436|reactome:R-RNO-68877|reactome:R-RNO-8852276|reactome:R-RNO-8955332|reactome:R-RNO-9646399|reactome:R-RNO-9648025|reactome:R-RNO-9668328|reactome:R-RNO-983189	-	-	-	figure legend:st1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10116(rat-hippocampus)|taxid:10116(Rattus norvegicus hippocampal neurons)	-	2020/10/30	2020/10/30	rogid:DtE+ZXAZKdCMvUW5K+jXQ5bH07M10116	rogid:CtggxXFLCJPeJvHksu32SCSlUfk10116	rigid:zzsc1zNhBb5nwIRPeFpYOKgC3M8	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q5XIE8	uniprotkb:P09495	intact:EBI-15348306|ensembl:ENSRNOP00000023037	intact:EBI-16221638|ensembl:ENSRNOP00000021073	psi-mi:itm2b_rat(display_long)|uniprotkb:Itm2b(gene name)|psi-mi:Itm2b(display_short)|uniprotkb:Immature BRI2(gene name synonym)|uniprotkb:Transmembrane protein BRI(gene name synonym)	psi-mi:tpm4_rat(display_long)|uniprotkb:Tpm4(gene name)|psi-mi:Tpm4(display_short)|uniprotkb:Tropomyosin-4(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Martins et al. (2018)	imex:IM-28469|pubmed:29476059	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26440627|imex:IM-28469-5	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSRNOG00000016271(gene)|ensembl:ENSRNOT00000023037(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001540"(amyloid-beta binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0010008"(endosome membrane)|go:"GO:0030660"(Golgi-associated vesicle membrane)|go:"GO:0031301"(integral component of organelle membrane)|go:"GO:0042985"(negative regulation of amyloid precursor protein biosynthetic process)|interpro:IPR007084(BRICHOS)|interpro:IPR040145|mint:Q5XIE8|refseq:NP_001006964.1|rgd:620727	ensembl:ENSRNOG00000015496(gene)|ensembl:ENSRNOT00000021073(transcript)|go:"GO:0001725"(stress fiber)|go:"GO:0002102"(podosome)|go:"GO:0005737"(cytoplasm)|go:"GO:0005884"(actin filament)|go:"GO:0006936"(muscle contraction)|go:"GO:0007015"(actin filament organization)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0030863"(cortical cytoskeleton)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0046872"(metal ion binding)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0051015"(actin filament binding)|interpro:IPR000533(Tropomyosin)|interpro:IPR014751(DNA double-strand break repair and VJ recombination XRCC4, C-terminal)|mint:P09495|reactome:R-RNO-390522|reactome:R-RNO-445355|reactome:R-RNO-9013424|rgd:3899|refseq:NP_036810.1	-	-	-	figure legend:st1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10116(rat-hippocampus)|taxid:10116(Rattus norvegicus hippocampal neurons)	-	2020/10/30	2020/10/30	rogid:DtE+ZXAZKdCMvUW5K+jXQ5bH07M10116	rogid:PmO3y3ayNgQt21g+uGAD8lMnvX810116	rigid:zzsc1zNhBb5nwIRPeFpYOKgC3M8	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q5XIE8	uniprotkb:Q60587	intact:EBI-15348306|ensembl:ENSRNOP00000023037	intact:EBI-918320|ensembl:ENSRNOP00000014637	psi-mi:itm2b_rat(display_long)|uniprotkb:Itm2b(gene name)|psi-mi:Itm2b(display_short)|uniprotkb:Immature BRI2(gene name synonym)|uniprotkb:Transmembrane protein BRI(gene name synonym)	psi-mi:echb_rat(display_long)|uniprotkb:Hadhb(gene name)|psi-mi:Hadhb(display_short)|uniprotkb:TP-beta(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Martins et al. (2018)	imex:IM-28469|pubmed:29476059	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26440627|imex:IM-28469-5	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSRNOG00000016271(gene)|ensembl:ENSRNOT00000023037(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001540"(amyloid-beta binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0010008"(endosome membrane)|go:"GO:0030660"(Golgi-associated vesicle membrane)|go:"GO:0031301"(integral component of organelle membrane)|go:"GO:0042985"(negative regulation of amyloid precursor protein biosynthetic process)|interpro:IPR007084(BRICHOS)|interpro:IPR040145|mint:Q5XIE8|refseq:NP_001006964.1|rgd:620727	rgd:620513|refseq:NP_598302.1|refseq:XP_006239848.2|refseq:XP_006239850.1|refseq:XP_006239851.1|ensembl:ENSRNOG00000010800(gene)|ensembl:ENSRNOT00000014637(transcript)|go:"GO:0003988"(acetyl-CoA C-acyltransferase activity)|go:"GO:0005739"(mitochondrion)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0006635"(fatty acid beta-oxidation)|go:"GO:0016507"(mitochondrial fatty acid beta-oxidation multienzyme complex)|go:"GO:0042645"(mitochondrial nucleoid)|go:"GO:0044877"(protein-containing complex binding)|interpro:IPR002155(Thiolase)|interpro:IPR016039(Thiolase-like)|interpro:IPR020610|interpro:IPR020613|interpro:IPR020615|interpro:IPR020616|interpro:IPR020617|mint:Q60587|reactome:R-RNO-1482798|reactome:R-RNO-77285|reactome:R-RNO-77305|reactome:R-RNO-77310|reactome:R-RNO-77346|reactome:R-RNO-77348|reactome:R-RNO-77350|go:"GO:0050633"(acetyl-CoA C-myristoyltransferase activity)	-	-	-	figure legend:st1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10116(rat-hippocampus)|taxid:10116(Rattus norvegicus hippocampal neurons)	-	2020/10/30	2020/10/30	rogid:DtE+ZXAZKdCMvUW5K+jXQ5bH07M10116	rogid:EEoW64ViK5odTwXLkE6zQWJgIAw10116	rigid:zzsc1zNhBb5nwIRPeFpYOKgC3M8	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q5XIE8	uniprotkb:Q5M7W4	intact:EBI-15348306|ensembl:ENSRNOP00000023037	intact:EBI-26440618	psi-mi:itm2b_rat(display_long)|uniprotkb:Itm2b(gene name)|psi-mi:Itm2b(display_short)|uniprotkb:Immature BRI2(gene name synonym)|uniprotkb:Transmembrane protein BRI(gene name synonym)	psi-mi:tmc5_rat(display_long)|uniprotkb:Tmc5(gene name)|psi-mi:Tmc5(display_short)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Martins et al. (2018)	imex:IM-28469|pubmed:29476059	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26440627|imex:IM-28469-5	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSRNOG00000016271(gene)|ensembl:ENSRNOT00000023037(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001540"(amyloid-beta binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0010008"(endosome membrane)|go:"GO:0030660"(Golgi-associated vesicle membrane)|go:"GO:0031301"(integral component of organelle membrane)|go:"GO:0042985"(negative regulation of amyloid precursor protein biosynthetic process)|interpro:IPR007084(BRICHOS)|interpro:IPR040145|mint:Q5XIE8|refseq:NP_001006964.1|rgd:620727	go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0008381"(mechanosensitive ion channel activity)|mint:Q5M7W4|refseq:NP_001012216.1|interpro:IPR038900|interpro:IPR012496(TMC)|rgd:1307037	-	-	-	figure legend:st1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10116(rat-hippocampus)|taxid:10116(Rattus norvegicus hippocampal neurons)	-	2020/10/30	2020/10/30	rogid:DtE+ZXAZKdCMvUW5K+jXQ5bH07M10116	rogid:6P/yUJq1dGAT0mNbTpX/59xH92s10116	rigid:zzsc1zNhBb5nwIRPeFpYOKgC3M8	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q5XIE8	uniprotkb:Q5U1Z2	intact:EBI-15348306|ensembl:ENSRNOP00000023037	intact:EBI-921025|ensembl:ENSRNOP00000014383	psi-mi:itm2b_rat(display_long)|uniprotkb:Itm2b(gene name)|psi-mi:Itm2b(display_short)|uniprotkb:Immature BRI2(gene name synonym)|uniprotkb:Transmembrane protein BRI(gene name synonym)	psi-mi:tppc3_rat(display_long)|uniprotkb:Trappc3(gene name)|psi-mi:Trappc3(display_short)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Martins et al. (2018)	imex:IM-28469|pubmed:29476059	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26440627|imex:IM-28469-5	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSRNOG00000016271(gene)|ensembl:ENSRNOT00000023037(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001540"(amyloid-beta binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0010008"(endosome membrane)|go:"GO:0030660"(Golgi-associated vesicle membrane)|go:"GO:0031301"(integral component of organelle membrane)|go:"GO:0042985"(negative regulation of amyloid precursor protein biosynthetic process)|interpro:IPR007084(BRICHOS)|interpro:IPR040145|mint:Q5XIE8|refseq:NP_001006964.1|rgd:620727	rgd:1309135|refseq:NP_001008377.1|ensembl:ENSRNOG00000010550(gene)|ensembl:ENSRNOT00000014383(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005829"(cytosol)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0006891"(intra-Golgi vesicle-mediated transport)|go:"GO:0030008"(TRAPP complex)|go:"GO:0033106"(cis-Golgi network membrane)|interpro:IPR007194("Transport protein particle (TRAPP) component, Bet3")|interpro:IPR016721(TRAPP I complex, Bet3)|interpro:IPR024096|mint:Q5U1Z2|reactome:R-RNO-204005|reactome:R-RNO-8876198	-	-	-	figure legend:st1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10116(rat-hippocampus)|taxid:10116(Rattus norvegicus hippocampal neurons)	-	2020/10/30	2020/10/30	rogid:DtE+ZXAZKdCMvUW5K+jXQ5bH07M10116	rogid:VoANjtqe/P6oziS0WRdNJprvMUI10116	rigid:zzsc1zNhBb5nwIRPeFpYOKgC3M8	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q5XIE8	uniprotkb:Q920J4	intact:EBI-15348306|ensembl:ENSRNOP00000023037	intact:EBI-919671|ensembl:ENSRNOP00000025510	psi-mi:itm2b_rat(display_long)|uniprotkb:Itm2b(gene name)|psi-mi:Itm2b(display_short)|uniprotkb:Immature BRI2(gene name synonym)|uniprotkb:Transmembrane protein BRI(gene name synonym)	psi-mi:txnl1_rat(display_long)|uniprotkb:Txnl1(gene name)|psi-mi:Txnl1(display_short)|uniprotkb:Trp(gene name synonym)|uniprotkb:Thioredoxin-related protein(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Martins et al. (2018)	imex:IM-28469|pubmed:29476059	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26440627|imex:IM-28469-5	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSRNOG00000016271(gene)|ensembl:ENSRNOT00000023037(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001540"(amyloid-beta binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0010008"(endosome membrane)|go:"GO:0030660"(Golgi-associated vesicle membrane)|go:"GO:0031301"(integral component of organelle membrane)|go:"GO:0042985"(negative regulation of amyloid precursor protein biosynthetic process)|interpro:IPR007084(BRICHOS)|interpro:IPR040145|mint:Q5XIE8|refseq:NP_001006964.1|rgd:620727	rgd:621717|refseq:NP_543163.1|ensembl:ENSRNOG00000018818(gene)|ensembl:ENSRNOT00000025510(transcript)|go:"GO:0000502"(proteasome complex)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0015036"(disulfide oxidoreductase activity)|interpro:IPR008979(Galactose-binding like)|interpro:IPR010400(Protein of unknown function DUF1000)|interpro:IPR013766(Thioredoxin domain)|interpro:IPR017937|interpro:IPR036249|interpro:IPR037047|mint:Q920J4|reactome:R-RNO-9013418|reactome:R-RNO-9013420|reactome:R-RNO-9013422|reactome:R-RNO-9013424|reactome:R-RNO-9696264|reactome:R-RNO-9696270|reactome:R-RNO-9696273	-	-	-	figure legend:st1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10116(rat-hippocampus)|taxid:10116(Rattus norvegicus hippocampal neurons)	-	2020/10/30	2020/10/30	rogid:DtE+ZXAZKdCMvUW5K+jXQ5bH07M10116	rogid:IdNjjpvOQpzmS+Tl8dmfF9O9yk010116	rigid:zzsc1zNhBb5nwIRPeFpYOKgC3M8	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q5XIE8	uniprotkb:Q66HR0	intact:EBI-15348306|ensembl:ENSRNOP00000023037	intact:EBI-15349225|uniprotkb:Q99NC8	psi-mi:itm2b_rat(display_long)|uniprotkb:Itm2b(gene name)|psi-mi:Itm2b(display_short)|uniprotkb:Immature BRI2(gene name synonym)|uniprotkb:Transmembrane protein BRI(gene name synonym)	psi-mi:s12a9_rat(display_long)|uniprotkb:Slc12a9(gene name)|psi-mi:Slc12a9(display_short)|uniprotkb:Ccc6(gene name synonym)|uniprotkb:Cation-chloride cotransporter 6(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Martins et al. (2018)	imex:IM-28469|pubmed:29476059	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26440627|imex:IM-28469-5	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSRNOG00000016271(gene)|ensembl:ENSRNOT00000023037(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001540"(amyloid-beta binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0010008"(endosome membrane)|go:"GO:0030660"(Golgi-associated vesicle membrane)|go:"GO:0031301"(integral component of organelle membrane)|go:"GO:0042985"(negative regulation of amyloid precursor protein biosynthetic process)|interpro:IPR007084(BRICHOS)|interpro:IPR040145|mint:Q5XIE8|refseq:NP_001006964.1|rgd:620727	go:"GO:0005886"(plasma membrane)|go:"GO:0006884"(cell volume homeostasis)|go:"GO:0015379"("potassium:chloride symporter activity")|go:"GO:0016021"(integral component of membrane)|go:"GO:0055064"(chloride ion homeostasis)|go:"GO:0055075"(potassium ion homeostasis)|go:"GO:1902476"(chloride transmembrane transport)|go:"GO:1990573"(potassium ion import across plasma membrane)|mint:Q66HR0|refseq:NP_599232.1|interpro:IPR004841(Amino acid permease-associated region)|interpro:IPR018491|interpro:IPR030345|rgd:620747	-	-	-	figure legend:st1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10116(rat-hippocampus)|taxid:10116(Rattus norvegicus hippocampal neurons)	-	2020/10/30	2020/10/30	rogid:DtE+ZXAZKdCMvUW5K+jXQ5bH07M10116	rogid:YAXuIzstPgFUU4o5zrgujLowsTk10116	rigid:zzsc1zNhBb5nwIRPeFpYOKgC3M8	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q5XIE8	uniprotkb:P11507	intact:EBI-15348306|ensembl:ENSRNOP00000023037	intact:EBI-916319|uniprotkb:P11508|ensembl:ENSRNOP00000024347	psi-mi:itm2b_rat(display_long)|uniprotkb:Itm2b(gene name)|psi-mi:Itm2b(display_short)|uniprotkb:Immature BRI2(gene name synonym)|uniprotkb:Transmembrane protein BRI(gene name synonym)	psi-mi:at2a2_rat(display_long)|uniprotkb:Calcium pump 2(gene name synonym)|uniprotkb:Calcium-transporting ATPase sarcoplasmic reticulum type, slow twitch skeletal muscle isoform(gene name synonym)|uniprotkb:"Endoplasmic reticulum class 1/2 Ca(2+) ATPase"(gene name synonym)|uniprotkb:Atp2a2(gene name)|psi-mi:Atp2a2(display_short)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Martins et al. (2018)	imex:IM-28469|pubmed:29476059	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26440627|imex:IM-28469-5	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSRNOG00000016271(gene)|ensembl:ENSRNOT00000023037(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001540"(amyloid-beta binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0010008"(endosome membrane)|go:"GO:0030660"(Golgi-associated vesicle membrane)|go:"GO:0031301"(integral component of organelle membrane)|go:"GO:0042985"(negative regulation of amyloid precursor protein biosynthetic process)|interpro:IPR007084(BRICHOS)|interpro:IPR040145|mint:Q5XIE8|refseq:NP_001006964.1|rgd:620727	ensembl:ENSRNOG00000001285(gene)|ensembl:ENSRNOT00000024347(transcript)|go:"GO:0000045"(autophagosome assembly)|go:"GO:0002026"(regulation of the force of heart contraction)|go:"GO:0003009"(skeletal muscle contraction)|go:"GO:0005388"(P-type calcium transporter activity)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006816"(calcium ion transport)|go:"GO:0006874"(cellular calcium ion homeostasis)|go:"GO:0006937"(regulation of muscle contraction)|go:"GO:0006984"(ER-nucleus signaling pathway)|go:"GO:0006996"(organelle organization)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008553"(P-type proton-exporting transporter activity)|go:"GO:0010882"(regulation of cardiac muscle contraction by calcium ion signaling)|go:"GO:0012506"(vesicle membrane)|go:"GO:0014883"(transition between fast and slow fiber)|go:"GO:0120025"(plasma membrane bounded cell projection)|go:"GO:0140056"(organelle localization by membrane tethering)|go:"GO:1900121"(negative regulation of receptor binding)|go:"GO:1903233"(regulation of calcium ion-dependent exocytosis of neurotransmitter)|go:"GO:1903515"(calcium ion transport from cytosol to endoplasmic reticulum)|go:"GO:1990036"(calcium ion import into sarcoplasmic reticulum)|go:"GO:1990456"(mitochondrion-endoplasmic reticulum membrane tethering)|interpro:IPR001757(ATPase, P-type, K/Mg/Cd/Cu/Zn/Na/Ca/Na/H-transporter)|interpro:IPR004014(ATPase, P-type cation-transporter, N-terminal)|interpro:IPR005782(Calcium ATPase)|interpro:IPR006068(ATPase, P-type cation-transporter, C-terminal)|interpro:IPR008250(E1-E2 ATPase-associated region)|interpro:IPR018303|interpro:IPR023214|interpro:IPR023298|interpro:IPR023299|interpro:IPR036412|interpro:IPR044492|mint:P11507|reactome:R-RNO-418359|reactome:R-RNO-5578775|reactome:R-RNO-936837|go:"GO:0014898"(cardiac muscle hypertrophy in response to stress)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016240"(autophagosome membrane docking)|go:"GO:0016529"(sarcoplasmic reticulum)|go:"GO:0019899"(enzyme binding)|go:"GO:0031234"(extrinsic component of cytoplasmic side of plasma membrane)|go:"GO:0031775"(lutropin-choriogonadotropic hormone receptor binding)|go:"GO:0032469"(endoplasmic reticulum calcium ion homeostasis)|go:"GO:0032470"(positive regulation of endoplasmic reticulum calcium ion concentration)|go:"GO:0032496"(response to lipopolysaccharide)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033017"(sarcoplasmic reticulum membrane)|go:"GO:0033292"(T-tubule organization)|go:"GO:0034599"(cellular response to oxidative stress)|go:"GO:0034605"(cellular response to heat)|go:"GO:0034976"(response to endoplasmic reticulum stress)|go:"GO:0043434"(response to peptide hormone)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0044548"(S100 protein binding)|go:"GO:0045822"(negative regulation of heart contraction)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0055119"(relaxation of cardiac muscle)|go:"GO:0061831"(apical ectoplasmic specialization)|go:"GO:0070296"(sarcoplasmic reticulum calcium ion transport)|go:"GO:0070588"(calcium ion transmembrane transport)|go:"GO:0086036"(regulation of cardiac muscle cell membrane potential)|go:"GO:0086039"(P-type calcium transporter activity involved in regulation of cardiac muscle cell membrane potential)|go:"GO:0097470"(ribbon synapse)|go:"GO:0098909"(regulation of cardiac muscle cell action potential involved in regulation of contraction)|rgd:2174|refseq:NP_001103609.1|refseq:NP_001104293.1	-	-	-	figure legend:st1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10116(rat-hippocampus)|taxid:10116(Rattus norvegicus hippocampal neurons)	-	2020/10/30	2020/10/30	rogid:DtE+ZXAZKdCMvUW5K+jXQ5bH07M10116	rogid:Et/ot4KEtlnq8iuoVL0CySJICIo10116	rigid:zzsc1zNhBb5nwIRPeFpYOKgC3M8	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q5XIE8	uniprotkb:P61227	intact:EBI-15348306|ensembl:ENSRNOP00000023037	intact:EBI-26440582|ensembl:ENSRNOP00000019340|uniprotkb:P17964|uniprotkb:Q96EG5|uniprotkb:Q9CXG0	psi-mi:itm2b_rat(display_long)|uniprotkb:Itm2b(gene name)|psi-mi:Itm2b(display_short)|uniprotkb:Immature BRI2(gene name synonym)|uniprotkb:Transmembrane protein BRI(gene name synonym)	psi-mi:rap2b_rat(display_long)|uniprotkb:Rap2b(gene name)|psi-mi:Rap2b(display_short)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Martins et al. (2018)	imex:IM-28469|pubmed:29476059	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26440627|imex:IM-28469-5	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSRNOG00000016271(gene)|ensembl:ENSRNOT00000023037(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001540"(amyloid-beta binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0010008"(endosome membrane)|go:"GO:0030660"(Golgi-associated vesicle membrane)|go:"GO:0031301"(integral component of organelle membrane)|go:"GO:0042985"(negative regulation of amyloid precursor protein biosynthetic process)|interpro:IPR007084(BRICHOS)|interpro:IPR040145|mint:Q5XIE8|refseq:NP_001006964.1|rgd:620727	ensembl:ENSRNOG00000014420(gene)|ensembl:ENSRNOT00000019340(transcript)|go:"GO:0003924"(GTPase activity)|go:"GO:0003925"(G protein activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005923"(bicellular tight junction)|go:"GO:0016020"(membrane)|go:"GO:0019003"(GDP binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030168"(platelet activation)|go:"GO:0030336"(negative regulation of cell migration)|go:"GO:0031954"(positive regulation of protein autophosphorylation)|go:"GO:0032486"(Rap protein signal transduction)|go:"GO:0044291"(cell-cell contact zone)|go:"GO:0045121"(membrane raft)|go:"GO:0055037"(recycling endosome)|go:"GO:0055038"(recycling endosome membrane)|go:"GO:0061097"(regulation of protein tyrosine kinase activity)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070527"(platelet aggregation)|interpro:IPR001806(Ras GTPase)|interpro:IPR005225(Small GTP-binding protein)|interpro:IPR020849|interpro:IPR027417|interpro:IPR041840|mint:P61227|reactome:R-RNO-6798695|refseq:NP_596901.1|rgd:620591	-	-	-	figure legend:st1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10116(rat-hippocampus)|taxid:10116(Rattus norvegicus hippocampal neurons)	-	2020/10/30	2020/10/30	rogid:DtE+ZXAZKdCMvUW5K+jXQ5bH07M10116	rogid:dFHHIYuDf3lTGSX0Nys6IE9ONvs10116	rigid:zzsc1zNhBb5nwIRPeFpYOKgC3M8	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q5XIE8	uniprotkb:Q8VBU2	intact:EBI-15348306|ensembl:ENSRNOP00000023037	intact:EBI-26373180|uniprotkb:Q8VBW2|uniprotkb:Q8VI00|uniprotkb:Q8VI01	psi-mi:itm2b_rat(display_long)|uniprotkb:Itm2b(gene name)|psi-mi:Itm2b(display_short)|uniprotkb:Immature BRI2(gene name synonym)|uniprotkb:Transmembrane protein BRI(gene name synonym)	psi-mi:ndrg2_rat(display_long)|uniprotkb:Antidepressant-related protein ADRG123(gene name synonym)|uniprotkb:N-myc downstream-regulated gene 2 protein(gene name synonym)|uniprotkb:NDRG1-related protein(gene name synonym)|uniprotkb:Ndrg2(gene name)|psi-mi:Ndrg2(display_short)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Martins et al. (2018)	imex:IM-28469|pubmed:29476059	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26440627|imex:IM-28469-5	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSRNOG00000016271(gene)|ensembl:ENSRNOT00000023037(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001540"(amyloid-beta binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0010008"(endosome membrane)|go:"GO:0030660"(Golgi-associated vesicle membrane)|go:"GO:0031301"(integral component of organelle membrane)|go:"GO:0042985"(negative regulation of amyloid precursor protein biosynthetic process)|interpro:IPR007084(BRICHOS)|interpro:IPR040145|mint:Q5XIE8|refseq:NP_001006964.1|rgd:620727	go:"GO:0001818"(negative regulation of cytokine production)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0007165"(signal transduction)|go:"GO:0007399"(nervous system development)|go:"GO:0010574"(regulation of vascular endothelial growth factor production)|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0030154"(cell differentiation)|go:"GO:0030426"(growth cone)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0048662"(negative regulation of smooth muscle cell proliferation)|go:"GO:0070373"(negative regulation of ERK1 and ERK2 cascade)|go:"GO:0090361"(regulation of platelet-derived growth factor production)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099173"(postsynapse organization)|rgd:621874|mint:Q8VBU2|refseq:NP_001257791.1|refseq:NP_001257792.1|refseq:NP_001257793.1|refseq:NP_598267.2|interpro:IPR029058|interpro:IPR004142(Ndr)|interpro:IPR030690	-	-	-	figure legend:st1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10116(rat-hippocampus)|taxid:10116(Rattus norvegicus hippocampal neurons)	-	2020/10/30	2020/10/30	rogid:DtE+ZXAZKdCMvUW5K+jXQ5bH07M10116	rogid:bYvOEJ0085f81U9/8b9gJHBoYmg10116	rigid:zzsc1zNhBb5nwIRPeFpYOKgC3M8	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q5XIE8	uniprotkb:Q6MG82	intact:EBI-15348306|ensembl:ENSRNOP00000023037	intact:EBI-26440562|ensembl:ENSRNOP00000000495	psi-mi:itm2b_rat(display_long)|uniprotkb:Itm2b(gene name)|psi-mi:Itm2b(display_short)|uniprotkb:Immature BRI2(gene name synonym)|uniprotkb:Transmembrane protein BRI(gene name synonym)	psi-mi:prrt1_rat(display_long)|uniprotkb:Prrt1(gene name)|psi-mi:Prrt1(display_short)|uniprotkb:Ng5(gene name synonym)|uniprotkb:Synapse differentiation-induced protein 4(gene name synonym)|uniprotkb:Dispanin subfamily D member 1(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Martins et al. (2018)	imex:IM-28469|pubmed:29476059	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26440627|imex:IM-28469-5	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSRNOG00000016271(gene)|ensembl:ENSRNOT00000023037(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001540"(amyloid-beta binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0010008"(endosome membrane)|go:"GO:0030660"(Golgi-associated vesicle membrane)|go:"GO:0031301"(integral component of organelle membrane)|go:"GO:0042985"(negative regulation of amyloid precursor protein biosynthetic process)|interpro:IPR007084(BRICHOS)|interpro:IPR040145|mint:Q5XIE8|refseq:NP_001006964.1|rgd:620727	go:"GO:0099055"(integral component of postsynaptic membrane)|go:"GO:2000311"(regulation of AMPA receptor activity)|interpro:IPR007593(Interferon-induced transmembrane protein)|mint:Q6MG82|go:"GO:0098978"(glutamatergic synapse)|ensembl:ENSRNOG00000000433(gene)|ensembl:ENSRNOT00000000495(transcript)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0007611"(learning or memory)|go:"GO:0008104"(protein localization)|go:"GO:0016020"(membrane)|go:"GO:0030545"(signaling receptor regulator activity)|go:"GO:0030672"(synaptic vesicle membrane)|go:"GO:0034394"(protein localization to cell surface)|go:"GO:0050808"(synapse organization)|go:"GO:0060291"(long-term synaptic potentiation)|go:"GO:0060292"(long-term synaptic depression)|go:"GO:0098839"(postsynaptic density membrane)|refseq:NP_001027456.1|rgd:1359348	-	-	-	figure legend:st1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10116(rat-hippocampus)|taxid:10116(Rattus norvegicus hippocampal neurons)	-	2020/10/30	2020/10/30	rogid:DtE+ZXAZKdCMvUW5K+jXQ5bH07M10116	rogid:ze0DL5c1LW/zyfYGTfJP+0jE8lM10116	rigid:zzsc1zNhBb5nwIRPeFpYOKgC3M8	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q5XIE8	uniprotkb:Q9JMJ4	intact:EBI-15348306|ensembl:ENSRNOP00000023037	intact:EBI-920056|uniprotkb:Q3B7C6|ensembl:ENSRNOP00000028373	psi-mi:itm2b_rat(display_long)|uniprotkb:Itm2b(gene name)|psi-mi:Itm2b(display_short)|uniprotkb:Immature BRI2(gene name synonym)|uniprotkb:Transmembrane protein BRI(gene name synonym)	psi-mi:prp19_rat(display_long)|uniprotkb:Prpf19(gene name)|psi-mi:Prpf19(display_short)|uniprotkb:Prp19(gene name synonym)|uniprotkb:PRP19/PSO4 homolog(gene name synonym)|uniprotkb:Neuronal differentiation-related gene protein(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase PRP19(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Martins et al. (2018)	imex:IM-28469|pubmed:29476059	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26440627|imex:IM-28469-5	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSRNOG00000016271(gene)|ensembl:ENSRNOT00000023037(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001540"(amyloid-beta binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0010008"(endosome membrane)|go:"GO:0030660"(Golgi-associated vesicle membrane)|go:"GO:0031301"(integral component of organelle membrane)|go:"GO:0042985"(negative regulation of amyloid precursor protein biosynthetic process)|interpro:IPR007084(BRICHOS)|interpro:IPR040145|mint:Q5XIE8|refseq:NP_001006964.1|rgd:620727	rgd:708496|refseq:NP_647549.2|ensembl:ENSRNOG00000020897(gene)|ensembl:ENSRNOT00000028373(transcript)|go:"GO:0000077"(DNA damage checkpoint signaling)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0000244"(spliceosomal tri-snRNP complex assembly)|go:"GO:0000245"(spliceosomal complex assembly)|go:"GO:0000349"(generation of catalytic spliceosome for first transesterification step)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0000974"(Prp19 complex)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005662"(DNA replication factor A complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0005811"(lipid droplet)|go:"GO:0005819"(spindle)|go:"GO:0006303"(double-strand break repair via nonhomologous end joining)|go:"GO:0008610"(lipid biosynthetic process)|go:"GO:0010498"(proteasomal protein catabolic process)|go:"GO:0016607"(nuclear speck)|go:"GO:0034450"(ubiquitin-ubiquitin ligase activity)|go:"GO:0034613"(cellular protein localization)|go:"GO:0035861"(site of double-strand break)|go:"GO:0042802"(identical protein binding)|go:"GO:0045666"(positive regulation of neuron differentiation)|go:"GO:0048026"(positive regulation of mRNA splicing, via spliceosome)|go:"GO:0048711"(positive regulation of astrocyte differentiation)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0070534"(protein K63-linked ubiquitination)|go:"GO:0071006"(U2-type catalytic step 1 spliceosome)|go:"GO:0071007"(U2-type catalytic step 2 spliceosome)|go:"GO:0071013"(catalytic step 2 spliceosome)|interpro:IPR000772(Ricin B lectin)|interpro:IPR001680(WD40 repeat)|interpro:IPR003613(U box)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR013915(Pre-mRNA-splicing factor 19)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019775|interpro:IPR020472|interpro:IPR036322|interpro:IPR038959|mint:Q9JMJ4|reactome:R-RNO-6781823|reactome:R-RNO-6782135|reactome:R-RNO-6782210|reactome:R-RNO-72163	-	-	-	figure legend:st1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10116(rat-hippocampus)|taxid:10116(Rattus norvegicus hippocampal neurons)	-	2020/10/30	2020/10/30	rogid:DtE+ZXAZKdCMvUW5K+jXQ5bH07M10116	rogid:y9TwQBT+caDGqphA61AR5ysoqRg10116	rigid:zzsc1zNhBb5nwIRPeFpYOKgC3M8	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q5XIE8	uniprotkb:Q64568	intact:EBI-15348306|ensembl:ENSRNOP00000023037	intact:EBI-26440511|uniprotkb:Q01489|uniprotkb:Q63444	psi-mi:itm2b_rat(display_long)|uniprotkb:Itm2b(gene name)|psi-mi:Itm2b(display_short)|uniprotkb:Immature BRI2(gene name synonym)|uniprotkb:Transmembrane protein BRI(gene name synonym)	psi-mi:at2b3_rat(display_long)|uniprotkb:Atp2b3(gene name)|psi-mi:Atp2b3(display_short)|uniprotkb:Pmca3(gene name synonym)|uniprotkb:Plasma membrane calcium ATPase isoform 3(gene name synonym)|uniprotkb:Plasma membrane calcium pump isoform 3(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Martins et al. (2018)	imex:IM-28469|pubmed:29476059	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26440627|imex:IM-28469-5	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSRNOG00000016271(gene)|ensembl:ENSRNOT00000023037(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001540"(amyloid-beta binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0010008"(endosome membrane)|go:"GO:0030660"(Golgi-associated vesicle membrane)|go:"GO:0031301"(integral component of organelle membrane)|go:"GO:0042985"(negative regulation of amyloid precursor protein biosynthetic process)|interpro:IPR007084(BRICHOS)|interpro:IPR040145|mint:Q5XIE8|refseq:NP_001006964.1|rgd:620727	go:"GO:0005388"(P-type calcium transporter activity)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006874"(cellular calcium ion homeostasis)|go:"GO:0007420"(brain development)|go:"GO:0015085"(calcium ion transmembrane transporter activity)|go:"GO:0019829"(ATPase-coupled cation transmembrane transporter activity)|go:"GO:0030165"(PDZ domain binding)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0045121"(membrane raft)|go:"GO:0046872"(metal ion binding)|go:"GO:0051480"(regulation of cytosolic calcium ion concentration)|go:"GO:0098688"(parallel fiber to Purkinje cell synapse)|go:"GO:0003407"(neural retina development)|go:"GO:0098982"(GABA-ergic synapse)|go:"GO:0099056"(integral component of presynaptic membrane)|go:"GO:1905056"(P-type calcium transporter activity involved in regulation of presynaptic cytosolic calcium ion concentration)|go:"GO:1990032"(parallel fiber)|go:"GO:1990034"(calcium ion export across plasma membrane)|reactome:R-RNO-418359|reactome:R-RNO-5578775|reactome:R-RNO-936837|go:"GO:0098978"(glutamatergic synapse)|mint:Q64568|refseq:NP_579822.1|refseq:XP_008771842.1|refseq:XP_017457435.1|refseq:XP_017457436.1|refseq:XP_017457437.1|interpro:IPR022141|interpro:IPR006068(ATPase, P-type cation-transporter, C-terminal)|interpro:IPR004014(ATPase, P-type cation-transporter, N-terminal)|interpro:IPR023299|interpro:IPR018303|interpro:IPR023298|interpro:IPR008250(E1-E2 ATPase-associated region)|interpro:IPR036412|interpro:IPR023214|interpro:IPR006408(Calcium-translocating P-type ATPase, PMCA-type)|interpro:IPR001757(ATPase, P-type, K/Mg/Cd/Cu/Zn/Na/Ca/Na/H-transporter)|rgd:621304|interpro:IPR044492	-	-	-	figure legend:st1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10116(rat-hippocampus)|taxid:10116(Rattus norvegicus hippocampal neurons)	-	2020/10/30	2020/10/30	rogid:DtE+ZXAZKdCMvUW5K+jXQ5bH07M10116	rogid:nBCw3xKC4dprl2BzR0RYfctbq5k10116	rigid:zzsc1zNhBb5nwIRPeFpYOKgC3M8	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q5XIE8	uniprotkb:Q9WU34	intact:EBI-15348306|ensembl:ENSRNOP00000023037	intact:EBI-2009341|uniprotkb:Q9R245|uniprotkb:Q9WU35	psi-mi:itm2b_rat(display_long)|uniprotkb:Itm2b(gene name)|psi-mi:Itm2b(display_short)|uniprotkb:Immature BRI2(gene name synonym)|uniprotkb:Transmembrane protein BRI(gene name synonym)	psi-mi:sept3_rat(display_long)|uniprotkb:Septin3(gene name)|psi-mi:Septin3(display_short)|uniprotkb:G-septin(gene name synonym)|uniprotkb:P40(gene name synonym)|uniprotkb:Sept3(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Martins et al. (2018)	imex:IM-28469|pubmed:29476059	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26440627|imex:IM-28469-5	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSRNOG00000016271(gene)|ensembl:ENSRNOT00000023037(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001540"(amyloid-beta binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0010008"(endosome membrane)|go:"GO:0030660"(Golgi-associated vesicle membrane)|go:"GO:0031301"(integral component of organelle membrane)|go:"GO:0042985"(negative regulation of amyloid precursor protein biosynthetic process)|interpro:IPR007084(BRICHOS)|interpro:IPR040145|mint:Q5XIE8|refseq:NP_001006964.1|rgd:620727	interpro:IPR030379|rgd:621745|refseq:NP_062248.1|interpro:IPR016491(Septin)|interpro:IPR008114(Septin 3)|mint:Q9WU34|interpro:IPR027417|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005829"(cytosol)|go:"GO:0005940"(septin ring)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0031105"(septin complex)|go:"GO:0032153"(cell division site)|go:"GO:0034613"(cellular protein localization)|go:"GO:0042734"(presynaptic membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0043005"(neuron projection)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0061640"(cytoskeleton-dependent cytokinesis)|go:"GO:0098793"(presynapse)|go:"GO:0099569"(presynaptic cytoskeleton)	-	-	-	figure legend:st1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10116(rat-hippocampus)|taxid:10116(Rattus norvegicus hippocampal neurons)	-	2020/10/30	2020/10/30	rogid:DtE+ZXAZKdCMvUW5K+jXQ5bH07M10116	rogid:6DWGiU+bROKg8mavCJZJ7kJwUUk10116	rigid:zzsc1zNhBb5nwIRPeFpYOKgC3M8	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q5XIE8	uniprotkb:P52504	intact:EBI-15348306|ensembl:ENSRNOP00000023037	intact:EBI-26440490	psi-mi:itm2b_rat(display_long)|uniprotkb:Itm2b(gene name)|psi-mi:Itm2b(display_short)|uniprotkb:Immature BRI2(gene name synonym)|uniprotkb:Transmembrane protein BRI(gene name synonym)	psi-mi:ndus6_rat(display_long)|uniprotkb:Ndufs6(gene name)|psi-mi:Ndufs6(display_short)|uniprotkb:Ip13(gene name synonym)|uniprotkb:Complex I-13kD-A(gene name synonym)|uniprotkb:NADH-ubiquinone oxidoreductase 13 kDa-A subunit(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Martins et al. (2018)	imex:IM-28469|pubmed:29476059	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26440627|imex:IM-28469-5	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSRNOG00000016271(gene)|ensembl:ENSRNOT00000023037(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001540"(amyloid-beta binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0010008"(endosome membrane)|go:"GO:0030660"(Golgi-associated vesicle membrane)|go:"GO:0031301"(integral component of organelle membrane)|go:"GO:0042985"(negative regulation of amyloid precursor protein biosynthetic process)|interpro:IPR007084(BRICHOS)|interpro:IPR040145|mint:Q5XIE8|refseq:NP_001006964.1|rgd:620727	go:"GO:0001822"(kidney development)|go:"GO:0005739"(mitochondrion)|go:"GO:0005747"(mitochondrial respiratory chain complex I)|go:"GO:0006120"(mitochondrial electron transport, NADH to ubiquinone)|go:"GO:0006631"(fatty acid metabolic process)|go:"GO:0006936"(muscle contraction)|go:"GO:0010259"(multicellular organism aging)|go:"GO:0022904"(respiratory electron transport chain)|go:"GO:0032981"(mitochondrial respiratory chain complex I assembly)|go:"GO:0035264"(multicellular organism growth)|go:"GO:0061458"(reproductive system development)|go:"GO:0070584"(mitochondrion morphogenesis)|go:"GO:0072359"(circulatory system development)|mint:P52504|refseq:NP_062096.1|interpro:IPR016668("NADH dehydrogenase [ubiquinone] (complex I), iron-sulphur protein 6, mitochondria")|interpro:IPR019401|rgd:3156	-	-	-	figure legend:st1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10116(rat-hippocampus)|taxid:10116(Rattus norvegicus hippocampal neurons)	-	2020/10/30	2020/10/30	rogid:DtE+ZXAZKdCMvUW5K+jXQ5bH07M10116	rogid:pbCEeNUkP/m1xZqmP8NEmSERrL410116	rigid:zzsc1zNhBb5nwIRPeFpYOKgC3M8	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q5XIE8	uniprotkb:Q5BK63	intact:EBI-15348306|ensembl:ENSRNOP00000023037	intact:EBI-921005|uniprotkb:B5DER7|ensembl:ENSRNOP00000072757	psi-mi:itm2b_rat(display_long)|uniprotkb:Itm2b(gene name)|psi-mi:Itm2b(display_short)|uniprotkb:Immature BRI2(gene name synonym)|uniprotkb:Transmembrane protein BRI(gene name synonym)	psi-mi:ndua9_rat(display_long)|uniprotkb:Ndufa9(gene name)|psi-mi:Ndufa9(display_short)|uniprotkb:NADH-ubiquinone oxidoreductase 39 kDa subunit(gene name synonym)|uniprotkb:Complex I-39kD(gene name synonym)|uniprotkb:Sperm flagella protein 3(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Martins et al. (2018)	imex:IM-28469|pubmed:29476059	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26440627|imex:IM-28469-5	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSRNOG00000016271(gene)|ensembl:ENSRNOT00000023037(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001540"(amyloid-beta binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0010008"(endosome membrane)|go:"GO:0030660"(Golgi-associated vesicle membrane)|go:"GO:0031301"(integral component of organelle membrane)|go:"GO:0042985"(negative regulation of amyloid precursor protein biosynthetic process)|interpro:IPR007084(BRICHOS)|interpro:IPR040145|mint:Q5XIE8|refseq:NP_001006964.1|rgd:620727	rgd:1307307|refseq:NP_001094222.1|ensembl:ENSRNOG00000061684(gene)|ensembl:ENSRNOT00000089193(transcript)|go:"GO:0003954"(NADH dehydrogenase activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005747"(mitochondrial respiratory chain complex I)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0007623"(circadian rhythm)|go:"GO:0009749"(response to glucose)|go:"GO:0031966"(mitochondrial membrane)|go:"GO:0032981"(mitochondrial respiratory chain complex I assembly)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:1901006"(ubiquinone-6 biosynthetic process)|interpro:IPR008030(NmrA-like)|interpro:IPR036291|mint:Q5BK63|reactome:R-RNO-611105|reactome:R-RNO-6799198	-	-	-	figure legend:st1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10116(rat-hippocampus)|taxid:10116(Rattus norvegicus hippocampal neurons)	-	2020/10/30	2020/10/30	rogid:DtE+ZXAZKdCMvUW5K+jXQ5bH07M10116	rogid:xF94AhPCBeZhicTmqc9oEprpUi410116	rigid:zzsc1zNhBb5nwIRPeFpYOKgC3M8	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q5XIE8	uniprotkb:P02600	intact:EBI-15348306|ensembl:ENSRNOP00000023037	intact:EBI-915764|ensembl:ENSRNOP00000017838|uniprotkb:P02601	psi-mi:itm2b_rat(display_long)|uniprotkb:Itm2b(gene name)|psi-mi:Itm2b(display_short)|uniprotkb:Immature BRI2(gene name synonym)|uniprotkb:Transmembrane protein BRI(gene name synonym)	psi-mi:myl1_rat(display_long)|uniprotkb:Myosin light chain alkali 1/2(gene name synonym)|uniprotkb:Myl1(gene name)|psi-mi:Myl1(display_short)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Martins et al. (2018)	imex:IM-28469|pubmed:29476059	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26440627|imex:IM-28469-5	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSRNOG00000016271(gene)|ensembl:ENSRNOT00000023037(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001540"(amyloid-beta binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0010008"(endosome membrane)|go:"GO:0030660"(Golgi-associated vesicle membrane)|go:"GO:0031301"(integral component of organelle membrane)|go:"GO:0042985"(negative regulation of amyloid precursor protein biosynthetic process)|interpro:IPR007084(BRICHOS)|interpro:IPR040145|mint:Q5XIE8|refseq:NP_001006964.1|rgd:620727	ensembl:ENSRNOG00000013262(gene)|ensembl:ENSRNOT00000017838(transcript)|go:"GO:0005509"(calcium ion binding)|go:"GO:0006936"(muscle contraction)|go:"GO:0008307"(structural constituent of muscle)|go:"GO:0016459"(myosin complex)|go:"GO:0030016"(myofibril)|go:"GO:0043292"(contractile fiber)|go:"GO:0060048"(cardiac muscle contraction)|interpro:IPR002048(Calcium-binding EF-hand)|interpro:IPR011992(EF-Hand type)|mint:P02600|reactome:R-RNO-390522|rgd:1598796|refseq:NP_001071124.1|refseq:NP_064489.1	-	-	-	figure legend:st1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10116(rat-hippocampus)|taxid:10116(Rattus norvegicus hippocampal neurons)	-	2020/10/30	2020/10/30	rogid:DtE+ZXAZKdCMvUW5K+jXQ5bH07M10116	rogid:Od8zPKeIcP9aXndQm+UvHjKubno10116	rigid:zzsc1zNhBb5nwIRPeFpYOKgC3M8	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q5XIE8	uniprotkb:Q9QZ76	intact:EBI-15348306|ensembl:ENSRNOP00000023037	intact:EBI-26440465|ensembl:ENSRNOP00000006184	psi-mi:itm2b_rat(display_long)|uniprotkb:Itm2b(gene name)|psi-mi:Itm2b(display_short)|uniprotkb:Immature BRI2(gene name synonym)|uniprotkb:Transmembrane protein BRI(gene name synonym)	psi-mi:myg_rat(display_long)|uniprotkb:Mb(gene name)|psi-mi:Mb(display_short)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Martins et al. (2018)	imex:IM-28469|pubmed:29476059	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26440627|imex:IM-28469-5	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSRNOG00000016271(gene)|ensembl:ENSRNOT00000023037(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001540"(amyloid-beta binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0010008"(endosome membrane)|go:"GO:0030660"(Golgi-associated vesicle membrane)|go:"GO:0031301"(integral component of organelle membrane)|go:"GO:0042985"(negative regulation of amyloid precursor protein biosynthetic process)|interpro:IPR007084(BRICHOS)|interpro:IPR040145|mint:Q5XIE8|refseq:NP_001006964.1|rgd:620727	go:"GO:0005344"(oxygen carrier activity)|go:"GO:0007507"(heart development)|go:"GO:0009725"(response to hormone)|go:"GO:0015671"(oxygen transport)|go:"GO:0019825"(oxygen binding)|go:"GO:0020037"(heme binding)|go:"GO:0031444"(slow-twitch skeletal muscle fiber contraction)|go:"GO:0042542"(response to hydrogen peroxide)|ensembl:ENSRNOG00000004583(gene)|ensembl:ENSRNOT00000006184(transcript)|go:"GO:0001666"(response to hypoxia)|go:"GO:0043353"(enucleate erythrocyte differentiation)|go:"GO:0046872"(metal ion binding)|go:"GO:0050873"(brown fat cell differentiation)|interpro:IPR000971(Globin, subset)|interpro:IPR002335(Myoglobin)|interpro:IPR009050(Globin-like)|mint:Q9QZ76|reactome:R-RNO-8981607|refseq:NP_067599.1|rgd:620411	-	-	-	figure legend:st1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10116(rat-hippocampus)|taxid:10116(Rattus norvegicus hippocampal neurons)	-	2020/10/30	2020/10/30	rogid:DtE+ZXAZKdCMvUW5K+jXQ5bH07M10116	rogid:aH4+zSr1efhbU9ArJKnSeooNGRo10116	rigid:zzsc1zNhBb5nwIRPeFpYOKgC3M8	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q5XIE8	uniprotkb:Q4L1J4	intact:EBI-15348306|ensembl:ENSRNOP00000023037	intact:EBI-5259666|uniprotkb:Q4L1J5	psi-mi:itm2b_rat(display_long)|uniprotkb:Itm2b(gene name)|psi-mi:Itm2b(display_short)|uniprotkb:Immature BRI2(gene name synonym)|uniprotkb:Transmembrane protein BRI(gene name synonym)	psi-mi:magi1_rat(display_long)|uniprotkb:Magi1(gene name)|psi-mi:Magi1(display_short)|uniprotkb:Baiap1(gene name synonym)|uniprotkb:Bap1(gene name synonym)|uniprotkb:BAI1-associated protein 1(gene name synonym)|uniprotkb:Membrane-associated guanylate kinase inverted 1(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Martins et al. (2018)	imex:IM-28469|pubmed:29476059	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26440627|imex:IM-28469-5	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSRNOG00000016271(gene)|ensembl:ENSRNOT00000023037(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001540"(amyloid-beta binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0010008"(endosome membrane)|go:"GO:0030660"(Golgi-associated vesicle membrane)|go:"GO:0031301"(integral component of organelle membrane)|go:"GO:0042985"(negative regulation of amyloid precursor protein biosynthetic process)|interpro:IPR007084(BRICHOS)|interpro:IPR040145|mint:Q5XIE8|refseq:NP_001006964.1|rgd:620727	interpro:IPR030033|mint:Q4L1J4|rgd:1586025|refseq:NP_001025216.1|interpro:IPR008144(Guanylate kinase)|interpro:IPR008145(Guanylate kinase/L-type calcium channel region)|interpro:IPR020590|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR001202(WW/Rsp5/WWP)|interpro:IPR027417|interpro:IPR036020|interpro:IPR036034|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005912"(adherens junction)|go:"GO:0005923"(bicellular tight junction)|go:"GO:0007165"(signal transduction)|go:"GO:0016020"(membrane)|go:"GO:0022409"(positive regulation of cell-cell adhesion)|go:"GO:0042995"(cell projection)|go:"GO:0051393"(alpha-actinin binding)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0071944"(cell periphery)	-	-	-	figure legend:st1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10116(rat-hippocampus)|taxid:10116(Rattus norvegicus hippocampal neurons)	-	2020/10/30	2020/10/30	rogid:DtE+ZXAZKdCMvUW5K+jXQ5bH07M10116	rogid:9CBhwilN2GVwCa7rk3mnHDORIU810116	rigid:zzsc1zNhBb5nwIRPeFpYOKgC3M8	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q5XIE8	uniprotkb:O08873	intact:EBI-15348306|ensembl:ENSRNOP00000023037	intact:EBI-26440430|ensembl:ENSRNOP00000017360	psi-mi:itm2b_rat(display_long)|uniprotkb:Itm2b(gene name)|psi-mi:Itm2b(display_short)|uniprotkb:Immature BRI2(gene name synonym)|uniprotkb:Transmembrane protein BRI(gene name synonym)	psi-mi:madd_rat(display_long)|uniprotkb:Madd(gene name)|psi-mi:Madd(display_short)|uniprotkb:Rab3 GDP/GTP exchange protein(gene name synonym)|uniprotkb:Rab3 GDP/GTP exchange factor(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Martins et al. (2018)	imex:IM-28469|pubmed:29476059	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26440627|imex:IM-28469-5	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSRNOG00000016271(gene)|ensembl:ENSRNOT00000023037(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001540"(amyloid-beta binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0010008"(endosome membrane)|go:"GO:0030660"(Golgi-associated vesicle membrane)|go:"GO:0031301"(integral component of organelle membrane)|go:"GO:0042985"(negative regulation of amyloid precursor protein biosynthetic process)|interpro:IPR007084(BRICHOS)|interpro:IPR040145|mint:Q5XIE8|refseq:NP_001006964.1|rgd:620727	go:"GO:0051726"(regulation of cell cycle)|go:"GO:0060125"(negative regulation of growth hormone secretion)|go:"GO:0097194"(execution phase of apoptosis)|go:"GO:1902041"(regulation of extrinsic apoptotic signaling pathway via death domain receptors)|go:"GO:1902277"(negative regulation of pancreatic amylase secretion)|go:"GO:1904115"(axon cytoplasm)|go:"GO:2001234"(negative regulation of apoptotic signaling pathway)|go:"GO:2001236"(regulation of extrinsic apoptotic signaling pathway)|interpro:IPR001194(DENN)|interpro:IPR005112(dDENN)|interpro:IPR005113(uDENN)|interpro:IPR037516|interpro:IPR039980|interpro:IPR043153|mint:O08873|reactome:R-RNO-5357905|reactome:R-RNO-8876198|go:"GO:0048490"(anterograde synaptic vesicle transport)|ensembl:ENSRNOG00000012568(gene)|ensembl:ENSRNOT00000017360(transcript)|go:"GO:0000187"(obsolete activation of MAPK activity)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0016021"(integral component of membrane)|go:"GO:0032483"(regulation of Rab protein signal transduction)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0045202"(synapse)|refseq:NP_446037.1|rgd:619922	-	-	-	figure legend:st1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10116(rat-hippocampus)|taxid:10116(Rattus norvegicus hippocampal neurons)	-	2020/10/30	2020/10/30	rogid:DtE+ZXAZKdCMvUW5K+jXQ5bH07M10116	rogid:cOkk61ececzBFxyENH7B++SxXDw10116	rigid:zzsc1zNhBb5nwIRPeFpYOKgC3M8	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q5XIE8	uniprotkb:P04636	intact:EBI-15348306|ensembl:ENSRNOP00000023037	intact:EBI-349293|ensembl:ENSRNOP00000001958|uniprotkb:Q6GSM4	psi-mi:itm2b_rat(display_long)|uniprotkb:Itm2b(gene name)|psi-mi:Itm2b(display_short)|uniprotkb:Immature BRI2(gene name synonym)|uniprotkb:Transmembrane protein BRI(gene name synonym)	psi-mi:mdhm_rat(display_long)|uniprotkb:Mdh2(gene name)|psi-mi:Mdh2(display_short)|uniprotkb:Mor1(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Martins et al. (2018)	imex:IM-28469|pubmed:29476059	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26440627|imex:IM-28469-5	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSRNOG00000016271(gene)|ensembl:ENSRNOT00000023037(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001540"(amyloid-beta binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0010008"(endosome membrane)|go:"GO:0030660"(Golgi-associated vesicle membrane)|go:"GO:0031301"(integral component of organelle membrane)|go:"GO:0042985"(negative regulation of amyloid precursor protein biosynthetic process)|interpro:IPR007084(BRICHOS)|interpro:IPR040145|mint:Q5XIE8|refseq:NP_001006964.1|rgd:620727	rgd:619719|refseq:NP_112413.2|ensembl:ENSRNOG00000001440(gene)|ensembl:ENSRNOT00000001958(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0005975"(carbohydrate metabolic process)|go:"GO:0006099"(tricarboxylic acid cycle)|go:"GO:0006107"(oxaloacetate metabolic process)|go:"GO:0006108"(malate metabolic process)|go:"GO:0006734"(NADH metabolic process)|go:"GO:0009060"(aerobic respiration)|go:"GO:0016020"(membrane)|go:"GO:0016615"(malate dehydrogenase activity)|go:"GO:0030060"(L-malate dehydrogenase activity)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043621"(protein self-association)|go:"GO:0046554"("malate dehydrogenase (NADP+) activity")|interpro:IPR001236(Lactate/malate dehydrogenase)|interpro:IPR001252(Malate dehydrogenase, active site)|interpro:IPR001557(L-lactate/malate dehydrogenase)|interpro:IPR010097(Malate dehydrogenase, NAD-dependent, eukaryotes and gamma proteobacteria)|interpro:IPR015955(Lactate dehydrogenase/glycoside hydrolase, family 4, C-terminal)|interpro:IPR022383|interpro:IPR036291|mint:P04636|reactome:R-RNO-70263|reactome:R-RNO-71403	-	-	-	figure legend:st1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10116(rat-hippocampus)|taxid:10116(Rattus norvegicus hippocampal neurons)	-	2020/10/30	2020/10/30	rogid:DtE+ZXAZKdCMvUW5K+jXQ5bH07M10116	rogid:Sa/YbZ/4mSQwdbOEyVs+4XfoUMg10116	rigid:zzsc1zNhBb5nwIRPeFpYOKgC3M8	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q5XIE8	uniprotkb:P04642	intact:EBI-15348306|ensembl:ENSRNOP00000023037	intact:EBI-349226|ensembl:ENSRNOP00000017468	psi-mi:itm2b_rat(display_long)|uniprotkb:Itm2b(gene name)|psi-mi:Itm2b(display_short)|uniprotkb:Immature BRI2(gene name synonym)|uniprotkb:Transmembrane protein BRI(gene name synonym)	psi-mi:ldha_rat(display_long)|uniprotkb:Ldha(gene name)|psi-mi:Ldha(display_short)|uniprotkb:Ldh-1(gene name synonym)|uniprotkb:Ldh1(gene name synonym)|uniprotkb:LDH muscle subunit(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Martins et al. (2018)	imex:IM-28469|pubmed:29476059	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26440627|imex:IM-28469-5	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSRNOG00000016271(gene)|ensembl:ENSRNOT00000023037(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001540"(amyloid-beta binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0010008"(endosome membrane)|go:"GO:0030660"(Golgi-associated vesicle membrane)|go:"GO:0031301"(integral component of organelle membrane)|go:"GO:0042985"(negative regulation of amyloid precursor protein biosynthetic process)|interpro:IPR007084(BRICHOS)|interpro:IPR040145|mint:Q5XIE8|refseq:NP_001006964.1|rgd:620727	rgd:2996|refseq:NP_058721.1|go:"GO:0004459"(L-lactate dehydrogenase activity)|go:"GO:0005829"(cytosol)|go:"GO:0006089"(lactate metabolic process)|go:"GO:0007584"(response to nutrient)|go:"GO:0009749"(response to glucose)|go:"GO:0014070"(response to organic cyclic compound)|go:"GO:0019661"(glucose catabolic process to lactate via pyruvate)|go:"GO:0019674"(NAD metabolic process)|go:"GO:0019900"(kinase binding)|go:"GO:0031668"(cellular response to extracellular stimulus)|go:"GO:0035686"(sperm fibrous sheath)|go:"GO:0042493"|go:"GO:0042542"(response to hydrogen peroxide)|go:"GO:0042802"(identical protein binding)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043627"(response to estrogen)|ensembl:ENSRNOG00000013009(gene)|ensembl:ENSRNOT00000017468(transcript)|go:"GO:0001666"(response to hypoxia)|go:"GO:0004457"(lactate dehydrogenase activity)|go:"GO:0048569"(post-embryonic animal organ development)|go:"GO:0051287"(NAD binding)|go:"GO:0051591"(response to cAMP)|interpro:IPR001236(Lactate/malate dehydrogenase)|interpro:IPR001557(L-lactate/malate dehydrogenase)|interpro:IPR011304(L-lactate dehydrogenase)|interpro:IPR015955(Lactate dehydrogenase/glycoside hydrolase, family 4, C-terminal)|interpro:IPR018177|interpro:IPR022383|interpro:IPR036291|mint:P04642|rcsb pdb:4AJ1|rcsb pdb:4AJ2|rcsb pdb:4AJ4|rcsb pdb:4AJE|rcsb pdb:4AJH|rcsb pdb:4AJI|rcsb pdb:4AJJ|rcsb pdb:4AJK|rcsb pdb:4AJL|rcsb pdb:4AJN|rcsb pdb:4AJO|rcsb pdb:4AL4|rcsb pdb:5ES3|reactome:R-RNO-70268	-	-	-	figure legend:st1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10116(rat-hippocampus)|taxid:10116(Rattus norvegicus hippocampal neurons)	-	2020/10/30	2020/10/30	rogid:DtE+ZXAZKdCMvUW5K+jXQ5bH07M10116	rogid:eKheC3CX/6TCkaYKpBsKggGzDXQ10116	rigid:zzsc1zNhBb5nwIRPeFpYOKgC3M8	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q5XIE8	uniprotkb:Q9QYU4	intact:EBI-15348306|ensembl:ENSRNOP00000023037	intact:EBI-26440404	psi-mi:itm2b_rat(display_long)|uniprotkb:Itm2b(gene name)|psi-mi:Itm2b(display_short)|uniprotkb:Immature BRI2(gene name synonym)|uniprotkb:Transmembrane protein BRI(gene name synonym)	psi-mi:crym_rat(display_long)|uniprotkb:Crym(gene name)|psi-mi:Crym(display_short)|uniprotkb:CDK108(gene name synonym)|uniprotkb:NADP-regulated thyroid-hormone-binding protein(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Martins et al. (2018)	imex:IM-28469|pubmed:29476059	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26440627|imex:IM-28469-5	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSRNOG00000016271(gene)|ensembl:ENSRNOT00000023037(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001540"(amyloid-beta binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0010008"(endosome membrane)|go:"GO:0030660"(Golgi-associated vesicle membrane)|go:"GO:0031301"(integral component of organelle membrane)|go:"GO:0042985"(negative regulation of amyloid precursor protein biosynthetic process)|interpro:IPR007084(BRICHOS)|interpro:IPR040145|mint:Q5XIE8|refseq:NP_001006964.1|rgd:620727	go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0006839"(mitochondrial transport)|go:"GO:0007605"(sensory perception of sound)|go:"GO:0009725"(response to hormone)|go:"GO:0033280"(response to vitamin D)|go:"GO:0042403"(thyroid hormone metabolic process)|go:"GO:0042562"(hormone binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0047127"(thiomorpholine-carboxylate dehydrogenase activity)|go:"GO:0050661"(NADP binding)|go:"GO:0070324"(thyroid hormone binding)|go:"GO:0070327"(thyroid hormone transport)|reactome:R-RNO-71064|mint:Q9QYU4|refseq:NP_446407.1|interpro:IPR036291|interpro:IPR003462(Ornithine cyclodeaminase/mu-crystallin)|interpro:IPR023401|rgd:620943	-	-	-	figure legend:st1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10116(rat-hippocampus)|taxid:10116(Rattus norvegicus hippocampal neurons)	-	2020/10/30	2020/10/30	rogid:DtE+ZXAZKdCMvUW5K+jXQ5bH07M10116	rogid:dgkNXDNxP8bjqdnNq+HgltU5MY410116	rigid:zzsc1zNhBb5nwIRPeFpYOKgC3M8	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q5XIE8	uniprotkb:Q63942	intact:EBI-15348306|ensembl:ENSRNOP00000023037	intact:EBI-6373552|uniprotkb:P35291|ensembl:ENSRNOP00000015609	psi-mi:itm2b_rat(display_long)|uniprotkb:Itm2b(gene name)|psi-mi:Itm2b(display_short)|uniprotkb:Immature BRI2(gene name synonym)|uniprotkb:Transmembrane protein BRI(gene name synonym)	psi-mi:rab3d_rat(display_long)|uniprotkb:Rab3d(gene name)|psi-mi:Rab3d(display_short)|uniprotkb:Rab16(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Martins et al. (2018)	imex:IM-28469|pubmed:29476059	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26440627|imex:IM-28469-5	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSRNOG00000016271(gene)|ensembl:ENSRNOT00000023037(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001540"(amyloid-beta binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0010008"(endosome membrane)|go:"GO:0030660"(Golgi-associated vesicle membrane)|go:"GO:0031301"(integral component of organelle membrane)|go:"GO:0042985"(negative regulation of amyloid precursor protein biosynthetic process)|interpro:IPR007084(BRICHOS)|interpro:IPR040145|mint:Q5XIE8|refseq:NP_001006964.1|rgd:620727	rgd:620924|refseq:NP_542147.1|ensembl:ENSRNOG00000011582(gene)|ensembl:ENSRNOT00000015609(transcript)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005768"(endosome)|go:"GO:0005881"(cytoplasmic microtubule)|go:"GO:0005886"(plasma membrane)|go:"GO:0006904"(vesicle docking involved in exocytosis)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0009306"(protein secretion)|go:"GO:0017157"(regulation of exocytosis)|go:"GO:0018125"(peptidyl-cysteine methylation)|go:"GO:0030133"(transport vesicle)|go:"GO:0030742"(GTP-dependent protein binding)|go:"GO:0031489"(myosin V binding)|go:"GO:0042588"(zymogen granule)|go:"GO:0045453"(bone resorption)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0099503"(secretory vesicle)|go:"GO:1903307"(positive regulation of regulated secretory pathway)|interpro:IPR001806(Ras GTPase)|interpro:IPR005225(Small GTP-binding protein)|interpro:IPR027417|interpro:IPR037872|mint:Q63942|reactome:R-RNO-6798695|reactome:R-RNO-8873719|refseq:XP_006242656.1|refseq:XP_017450911.1	-	-	-	figure legend:st1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10116(rat-hippocampus)|taxid:10116(Rattus norvegicus hippocampal neurons)	-	2020/10/30	2020/10/30	rogid:DtE+ZXAZKdCMvUW5K+jXQ5bH07M10116	rogid:D8rRi9Hoc/ZJ+9SG1xc/g1n1hc810116	rigid:zzsc1zNhBb5nwIRPeFpYOKgC3M8	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q5XIE8	uniprotkb:P35571	intact:EBI-15348306|ensembl:ENSRNOP00000023037	intact:EBI-22253313	psi-mi:itm2b_rat(display_long)|uniprotkb:Itm2b(gene name)|psi-mi:Itm2b(display_short)|uniprotkb:Immature BRI2(gene name synonym)|uniprotkb:Transmembrane protein BRI(gene name synonym)	psi-mi:gpdm_rat(display_long)|uniprotkb:Gpd2(gene name)|psi-mi:Gpd2(display_short)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Martins et al. (2018)	imex:IM-28469|pubmed:29476059	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26440627|imex:IM-28469-5	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSRNOG00000016271(gene)|ensembl:ENSRNOT00000023037(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001540"(amyloid-beta binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0010008"(endosome membrane)|go:"GO:0030660"(Golgi-associated vesicle membrane)|go:"GO:0031301"(integral component of organelle membrane)|go:"GO:0042985"(negative regulation of amyloid precursor protein biosynthetic process)|interpro:IPR007084(BRICHOS)|interpro:IPR040145|mint:Q5XIE8|refseq:NP_001006964.1|rgd:620727	go:"GO:0004367"(glycerol-3-phosphate dehydrogenase [NAD+] activity)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005739"(mitochondrion)|go:"GO:0006072"(glycerol-3-phosphate metabolic process)|go:"GO:0006094"(gluconeogenesis)|go:"GO:0006734"(NADH metabolic process)|go:"GO:0009331"(glycerol-3-phosphate dehydrogenase complex)|go:"GO:0019563"(glycerol catabolic process)|go:"GO:0035264"(multicellular organism growth)|go:"GO:0043010"(camera-type eye development)|go:"GO:0052591"("sn-glycerol-3-phosphate:ubiquinone-8 oxidoreductase activity")|reactome:R-RNO-1483166|reactome:R-RNO-163560|mint:P35571|rgd:2726|refseq:NP_036868.1|interpro:IPR031656|interpro:IPR038299|interpro:IPR011992(EF-Hand type)|interpro:IPR018247|interpro:IPR002048(Calcium-binding EF-hand)|interpro:IPR006076(FAD dependent oxidoreductase)|interpro:IPR036188|interpro:IPR000447(FAD-dependent glycerol-3-phosphate dehydrogenase)	-	-	-	figure legend:st1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10116(rat-hippocampus)|taxid:10116(Rattus norvegicus hippocampal neurons)	-	2020/10/30	2020/10/30	rogid:DtE+ZXAZKdCMvUW5K+jXQ5bH07M10116	rogid:HvoC5Ym4sV48YM1D9f+UMeFwrVs10116	rigid:zzsc1zNhBb5nwIRPeFpYOKgC3M8	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q5XIE8	uniprotkb:P28492	intact:EBI-15348306|ensembl:ENSRNOP00000023037	intact:EBI-26440376|uniprotkb:Q3MHS6|uniprotkb:Q5FVU0|uniprotkb:Q64606	psi-mi:itm2b_rat(display_long)|uniprotkb:Itm2b(gene name)|psi-mi:Itm2b(display_short)|uniprotkb:Immature BRI2(gene name synonym)|uniprotkb:Transmembrane protein BRI(gene name synonym)	psi-mi:glsl_rat(display_long)|uniprotkb:Gls2(gene name)|psi-mi:Gls2(display_short)|uniprotkb:Ga(gene name synonym)|uniprotkb:L-glutaminase(gene name synonym)|uniprotkb:L-glutamine amidohydrolase(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Martins et al. (2018)	imex:IM-28469|pubmed:29476059	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26440627|imex:IM-28469-5	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSRNOG00000016271(gene)|ensembl:ENSRNOT00000023037(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001540"(amyloid-beta binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0010008"(endosome membrane)|go:"GO:0030660"(Golgi-associated vesicle membrane)|go:"GO:0031301"(integral component of organelle membrane)|go:"GO:0042985"(negative regulation of amyloid precursor protein biosynthetic process)|interpro:IPR007084(BRICHOS)|interpro:IPR040145|mint:Q5XIE8|refseq:NP_001006964.1|rgd:620727	go:"GO:0004359"(glutaminase activity)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0006537"(glutamate biosynthetic process)|go:"GO:0006543"(glutamine catabolic process)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0072593"(reactive oxygen species metabolic process)|reactome:R-RNO-210500|reactome:R-RNO-5628897|reactome:R-RNO-8964539|go:"GO:0005739"(mitochondrion)|mint:P28492|refseq:NP_001257715.1|refseq:NP_001257716.1|refseq:NP_620259.2|refseq:XP_006240792.1|interpro:IPR002110(Ankyrin)|interpro:IPR020683|interpro:IPR036770|interpro:IPR012338(Beta-lactamase-type transpeptidase fold)|interpro:IPR015868(Glutaminase, core)|interpro:IPR041541|rgd:620359	-	-	-	figure legend:st1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10116(rat-hippocampus)|taxid:10116(Rattus norvegicus hippocampal neurons)	-	2020/10/30	2020/10/30	rogid:DtE+ZXAZKdCMvUW5K+jXQ5bH07M10116	rogid:7oTz2ijDMq1ANm2BpnN/iQa0kRA10116	rigid:zzsc1zNhBb5nwIRPeFpYOKgC3M8	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q5XIE8	uniprotkb:P12785	intact:EBI-15348306|ensembl:ENSRNOP00000023037	intact:EBI-493558|uniprotkb:O09187|uniprotkb:O09190|uniprotkb:Q63577|uniprotkb:Q64717|ensembl:ENSRNOP00000064445	psi-mi:itm2b_rat(display_long)|uniprotkb:Itm2b(gene name)|psi-mi:Itm2b(display_short)|uniprotkb:Immature BRI2(gene name synonym)|uniprotkb:Transmembrane protein BRI(gene name synonym)	psi-mi:fas_rat(display_long)|uniprotkb:Type I FAS(gene name synonym)|uniprotkb:Fasn(gene name)|psi-mi:Fasn(display_short)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Martins et al. (2018)	imex:IM-28469|pubmed:29476059	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26440627|imex:IM-28469-5	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSRNOG00000016271(gene)|ensembl:ENSRNOT00000023037(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001540"(amyloid-beta binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0010008"(endosome membrane)|go:"GO:0030660"(Golgi-associated vesicle membrane)|go:"GO:0031301"(integral component of organelle membrane)|go:"GO:0042985"(negative regulation of amyloid precursor protein biosynthetic process)|interpro:IPR007084(BRICHOS)|interpro:IPR040145|mint:Q5XIE8|refseq:NP_001006964.1|rgd:620727	rgd:620665|refseq:NP_059028.1|ensembl:ENSRNOG00000045636(gene)|ensembl:ENSRNOT00000073321(transcript)|go:"GO:0002068"(glandular epithelial cell development)|go:"GO:0004312"(fatty acid synthase activity)|go:"GO:0004313"([acyl-carrier-protein] S-acetyltransferase activity)|go:"GO:0004314"([acyl-carrier-protein] S-malonyltransferase activity)|go:"GO:0004315"(3-oxoacyl-[acyl-carrier-protein] synthase activity)|go:"GO:0004316"("3-oxoacyl-[acyl-carrier-protein] reductase (NADPH) activity")|go:"GO:0004317"(3-hydroxypalmitoyl-[acyl-carrier-protein] dehydratase activity)|go:"GO:0004320"(oleoyl-[acyl-carrier-protein] hydrolase activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006084"(acetyl-CoA metabolic process)|go:"GO:0006633"(fatty acid biosynthetic process)|go:"GO:0008610"(lipid biosynthetic process)|go:"GO:0008611"(ether lipid biosynthetic process)|go:"GO:0008659"("(3R)-hydroxymyristoyl-[acyl-carrier-protein] dehydratase activity")|go:"GO:0008693"(3-hydroxydecanoyl-[acyl-carrier-protein] dehydratase activity)|go:"GO:0009888"(tissue development)|go:"GO:0016295"(myristoyl-[acyl-carrier-protein] hydrolase activity)|go:"GO:0016296"(palmitoyl-[acyl-carrier-protein] hydrolase activity)|go:"GO:0030223"(neutrophil differentiation)|go:"GO:0030224"(monocyte differentiation)|go:"GO:0030879"(mammary gland development)|go:"GO:0031177"(phosphopantetheine binding)|go:"GO:0042470"(melanosome)|go:"GO:0042587"(glycogen granule)|go:"GO:0042802"(identical protein binding)|go:"GO:0047117"("enoyl-[acyl-carrier-protein] reductase (NADPH, A-specific) activity")|go:"GO:0047451"(3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity)|go:"GO:0071353"(cellular response to interleukin-4)|go:"GO:0090557"(establishment of endothelial intestinal barrier)|go:"GO:0102131"(obsolete 3-oxo-glutaryl-[acp] methyl ester reductase activity)|go:"GO:0102132"(obsolete 3-oxo-pimeloyl-[acp] methyl ester reductase activity)|interpro:IPR001031(Thioesterase)|interpro:IPR001227(Acyl transferase region)|interpro:IPR006162(Phosphopantetheine attachment site)|interpro:IPR009081(Acyl carrier protein-like)|interpro:IPR011032(GroES-like)|interpro:IPR013149(Alcohol dehydrogenase, zinc-binding)|interpro:IPR013217(Methyltransferase type 12)|interpro:IPR013968(Polyketide synthase, KR)|interpro:IPR014030(Beta-ketoacyl synthase, N-terminal)|interpro:IPR014031(Beta-ketoacyl synthase, C-terminal)|interpro:IPR014043(Acyl transferase)|interpro:IPR016035(Acyl transferase/acyl hydrolase/lysophospholipase)|interpro:IPR016036(Malonyl-CoA ACP transacylase, ACP-binding)|interpro:IPR016039(Thiolase-like)|interpro:IPR018201|interpro:IPR020806|interpro:IPR020807|interpro:IPR020841|interpro:IPR020843|interpro:IPR029058|interpro:IPR029063|interpro:IPR032821|interpro:IPR036291|interpro:IPR036736|interpro:IPR042104|mint:P12785|rcsb pdb:2PNG|reactome:R-RNO-163765|reactome:R-RNO-199220|reactome:R-RNO-75105|dip:DIP-33893N	-	-	-	figure legend:st1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10116(rat-hippocampus)|taxid:10116(Rattus norvegicus hippocampal neurons)	-	2020/10/30	2020/10/30	rogid:DtE+ZXAZKdCMvUW5K+jXQ5bH07M10116	rogid:wCACMgAvWJBkhev3sLlnfdqVJ1U10116	rigid:zzsc1zNhBb5nwIRPeFpYOKgC3M8	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q5XIE8	uniprotkb:Q8R491	intact:EBI-15348306|ensembl:ENSRNOP00000023037	intact:EBI-919578|ensembl:ENSRNOP00000010419	psi-mi:itm2b_rat(display_long)|uniprotkb:Itm2b(gene name)|psi-mi:Itm2b(display_short)|uniprotkb:Immature BRI2(gene name synonym)|uniprotkb:Transmembrane protein BRI(gene name synonym)	psi-mi:ehd3_rat(display_long)|uniprotkb:Ehd3(gene name)|psi-mi:Ehd3(display_short)|uniprotkb:Ehd2(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Martins et al. (2018)	imex:IM-28469|pubmed:29476059	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26440627|imex:IM-28469-5	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSRNOG00000016271(gene)|ensembl:ENSRNOT00000023037(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001540"(amyloid-beta binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0010008"(endosome membrane)|go:"GO:0030660"(Golgi-associated vesicle membrane)|go:"GO:0031301"(integral component of organelle membrane)|go:"GO:0042985"(negative regulation of amyloid precursor protein biosynthetic process)|interpro:IPR007084(BRICHOS)|interpro:IPR040145|mint:Q5XIE8|refseq:NP_001006964.1|rgd:620727	rgd:621762|refseq:NP_620245.2|ensembl:ENSRNOG00000007744(gene)|ensembl:ENSRNOT00000010419(transcript)|go:"GO:0001881"(receptor recycling)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005525"(GTP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005769"(early endosome)|go:"GO:0005829"(cytosol)|go:"GO:0006897"(endocytosis)|go:"GO:0015031"(protein transport)|go:"GO:0016197"(endosomal transport)|go:"GO:0020018"(ciliary pocket membrane)|go:"GO:0030139"(endocytic vesicle)|go:"GO:0032456"(endocytic recycling)|go:"GO:0034498"(early endosome to Golgi transport)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051260"(protein homooligomerization)|go:"GO:0055038"(recycling endosome membrane)|go:"GO:0055117"(regulation of cardiac muscle contraction)|go:"GO:0060271"(cilium assembly)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0086036"(regulation of cardiac muscle cell membrane potential)|go:"GO:0090160"(Golgi to lysosome transport)|go:"GO:1901387"(positive regulation of voltage-gated calcium channel activity)|go:"GO:1903358"(regulation of Golgi organization)|go:"GO:1903779"(regulation of cardiac conduction)|interpro:IPR000261("EPS15 homology (EH)")|interpro:IPR002048(Calcium-binding EF-hand)|interpro:IPR011992(EF-Hand type)|interpro:IPR018247|interpro:IPR022812|interpro:IPR027417|interpro:IPR029951|interpro:IPR030381|interpro:IPR031692|interpro:IPR040990|mint:Q8R491|reactome:R-RNO-983231	-	-	-	figure legend:st1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10116(rat-hippocampus)|taxid:10116(Rattus norvegicus hippocampal neurons)	-	2020/10/30	2020/10/30	rogid:DtE+ZXAZKdCMvUW5K+jXQ5bH07M10116	rogid:9FAMZNs3vpOwzZ2odo1sjLPBqlQ10116	rigid:zzsc1zNhBb5nwIRPeFpYOKgC3M8	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q5XIE8	uniprotkb:P35171	intact:EBI-15348306|ensembl:ENSRNOP00000023037	intact:EBI-21296621|ensembl:ENSRNOP00000060398	psi-mi:itm2b_rat(display_long)|uniprotkb:Itm2b(gene name)|psi-mi:Itm2b(display_short)|uniprotkb:Immature BRI2(gene name synonym)|uniprotkb:Transmembrane protein BRI(gene name synonym)	psi-mi:cx7a2_rat(display_long)|uniprotkb:Cox7a2(gene name)|psi-mi:Cox7a2(display_short)|uniprotkb:Cox7a3(gene name synonym)|uniprotkb:Cox7al(gene name synonym)|uniprotkb:Cytochrome c oxidase subunit VIIa-liver/heart(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Martins et al. (2018)	imex:IM-28469|pubmed:29476059	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26440627|imex:IM-28469-5	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSRNOG00000016271(gene)|ensembl:ENSRNOT00000023037(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001540"(amyloid-beta binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0010008"(endosome membrane)|go:"GO:0030660"(Golgi-associated vesicle membrane)|go:"GO:0031301"(integral component of organelle membrane)|go:"GO:0042985"(negative regulation of amyloid precursor protein biosynthetic process)|interpro:IPR007084(BRICHOS)|interpro:IPR040145|mint:Q5XIE8|refseq:NP_001006964.1|rgd:620727	ensembl:ENSRNOG00000042903(gene)|ensembl:ENSRNOT00000066084(transcript)|go:"GO:0002082"(regulation of oxidative phosphorylation)|go:"GO:0005746"(mitochondrial respirasome)|go:"GO:0005751"(mitochondrial respiratory chain complex IV)|go:"GO:0006123"(mitochondrial electron transport, cytochrome c to oxygen)|go:"GO:0009055"(electron transfer activity)|go:"GO:0016021"(integral component of membrane)|go:"GO:0097250"(mitochondrial respirasome assembly)|interpro:IPR003177(Cytochrome c oxidase, subunit VIIa)|interpro:IPR036539|interpro:IPR039297|mint:P35171|refseq:NP_071948.1|refseq:XP_003751415.1|refseq:XP_003752782.1|rgd:68365	-	-	-	figure legend:st1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10116(rat-hippocampus)|taxid:10116(Rattus norvegicus hippocampal neurons)	-	2020/10/30	2020/10/30	rogid:DtE+ZXAZKdCMvUW5K+jXQ5bH07M10116	rogid:5bxmh/dY58vxi7yFkpM38hxdZhY10116	rigid:zzsc1zNhBb5nwIRPeFpYOKgC3M8	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q5XIE8	uniprotkb:P11951	intact:EBI-15348306|ensembl:ENSRNOP00000023037	intact:EBI-26440359|ensembl:ENSRNOP00000014407|uniprotkb:Q63703	psi-mi:itm2b_rat(display_long)|uniprotkb:Itm2b(gene name)|psi-mi:Itm2b(display_short)|uniprotkb:Immature BRI2(gene name synonym)|uniprotkb:Transmembrane protein BRI(gene name synonym)	psi-mi:cx6c2_rat(display_long)|uniprotkb:Cox6c2(gene name)|psi-mi:Cox6c2(display_short)|uniprotkb:Cox6c(gene name synonym)|uniprotkb:Cytochrome c oxidase polypeptide VIc-2(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Martins et al. (2018)	imex:IM-28469|pubmed:29476059	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26440627|imex:IM-28469-5	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSRNOG00000016271(gene)|ensembl:ENSRNOT00000023037(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001540"(amyloid-beta binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0010008"(endosome membrane)|go:"GO:0030660"(Golgi-associated vesicle membrane)|go:"GO:0031301"(integral component of organelle membrane)|go:"GO:0042985"(negative regulation of amyloid precursor protein biosynthetic process)|interpro:IPR007084(BRICHOS)|interpro:IPR040145|mint:Q5XIE8|refseq:NP_001006964.1|rgd:620727	ensembl:ENSRNOT00000014407(transcript)|go:"GO:0004129"(cytochrome-c oxidase activity)|go:"GO:0005751"(mitochondrial respiratory chain complex IV)|go:"GO:0006123"(mitochondrial electron transport, cytochrome c to oxygen)|go:"GO:0016021"(integral component of membrane)|interpro:IPR004204(Cytochrome c oxidase subunit VIc)|interpro:IPR034884|interpro:IPR037169|mint:P11951|ensembl:ENSRNOG00000010807(gene)|refseq:NP_062233.2|rgd:620616	-	-	-	figure legend:st1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10116(rat-hippocampus)|taxid:10116(Rattus norvegicus hippocampal neurons)	-	2020/10/30	2020/10/30	rogid:DtE+ZXAZKdCMvUW5K+jXQ5bH07M10116	rogid:87gE+k3HgqEKqufv619YrX0jjfU10116	rigid:zzsc1zNhBb5nwIRPeFpYOKgC3M8	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q5XIE8	uniprotkb:P00406	intact:EBI-15348306|ensembl:ENSRNOP00000023037	intact:EBI-26440326|ensembl:ENSRNOP00000046414|uniprotkb:Q37738|uniprotkb:Q80WI7	psi-mi:itm2b_rat(display_long)|uniprotkb:Itm2b(gene name)|psi-mi:Itm2b(display_short)|uniprotkb:Immature BRI2(gene name synonym)|uniprotkb:Transmembrane protein BRI(gene name synonym)	psi-mi:cox2_rat(display_long)|uniprotkb:Mtco2(gene name)|psi-mi:Mtco2(display_short)|uniprotkb:Coii(gene name synonym)|uniprotkb:COX2(gene name synonym)|uniprotkb:mt-Co2(gene name synonym)|uniprotkb:Cytochrome c oxidase polypeptide II(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Martins et al. (2018)	imex:IM-28469|pubmed:29476059	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26440627|imex:IM-28469-5	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSRNOG00000016271(gene)|ensembl:ENSRNOT00000023037(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001540"(amyloid-beta binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0010008"(endosome membrane)|go:"GO:0030660"(Golgi-associated vesicle membrane)|go:"GO:0031301"(integral component of organelle membrane)|go:"GO:0042985"(negative regulation of amyloid precursor protein biosynthetic process)|interpro:IPR007084(BRICHOS)|interpro:IPR040145|mint:Q5XIE8|refseq:NP_001006964.1|rgd:620727	ensembl:ENSRNOG00000030371(gene)|ensembl:ENSRNOT00000043693(transcript)|go:"GO:0004129"(cytochrome-c oxidase activity)|go:"GO:0005507"(copper ion binding)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0007595"(lactation)|go:"GO:0009409"(response to cold)|go:"GO:0010729"(positive regulation of hydrogen peroxide biosynthetic process)|go:"GO:0010940"(positive regulation of necrotic cell death)|go:"GO:0016021"(integral component of membrane)|go:"GO:0042773"(ATP synthesis coupled electron transport)|go:"GO:0045277"(respiratory chain complex IV)|go:"GO:2001171"(positive regulation of ATP biosynthetic process)|interpro:IPR001505("Copper centre Cu(A)")|interpro:IPR002429(Cytochrome c oxidase subunit II C-terminal)|interpro:IPR008972(Cupredoxin)|interpro:IPR011759(Cytochrome C oxidase subunit II, transmembrane region)|interpro:IPR014222(Cytochrome c oxidase, subunit II)|interpro:IPR034210|interpro:IPR036257|mint:P00406|reactome:R-RNO-5628897|reactome:R-RNO-611105|reactome:R-RNO-9707564|refseq:AP_004895.1|refseq:YP_665632.1|rgd:621872	-	-	-	figure legend:st1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10116(rat-hippocampus)|taxid:10116(Rattus norvegicus hippocampal neurons)	-	2020/10/30	2020/10/30	rogid:DtE+ZXAZKdCMvUW5K+jXQ5bH07M10116	rogid:zm/VVIj5htxT5KqIB5bgSTEKmNE10116	rigid:zzsc1zNhBb5nwIRPeFpYOKgC3M8	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q5XIE8	uniprotkb:O08565	intact:EBI-15348306|ensembl:ENSRNOP00000023037	intact:EBI-11167786|ensembl:ENSRNOP00000005143|uniprotkb:F1LPN8|uniprotkb:Q8VD47	psi-mi:itm2b_rat(display_long)|uniprotkb:Itm2b(gene name)|psi-mi:Itm2b(display_short)|uniprotkb:Immature BRI2(gene name synonym)|uniprotkb:Transmembrane protein BRI(gene name synonym)	psi-mi:cxcr4_rat(display_long)|uniprotkb:Cxcr4(gene name)|psi-mi:Cxcr4(display_short)|uniprotkb:Cmkar4(gene name synonym)|uniprotkb:Fusin(gene name synonym)|uniprotkb:Leukocyte-derived seven transmembrane domain receptor(gene name synonym)|uniprotkb:Stromal cell-derived factor 1 receptor(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Martins et al. (2018)	imex:IM-28469|pubmed:29476059	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26440627|imex:IM-28469-5	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSRNOG00000016271(gene)|ensembl:ENSRNOT00000023037(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001540"(amyloid-beta binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0010008"(endosome membrane)|go:"GO:0030660"(Golgi-associated vesicle membrane)|go:"GO:0031301"(integral component of organelle membrane)|go:"GO:0042985"(negative regulation of amyloid precursor protein biosynthetic process)|interpro:IPR007084(BRICHOS)|interpro:IPR040145|mint:Q5XIE8|refseq:NP_001006964.1|rgd:620727	rgd:620465|ensembl:ENSRNOG00000003866(gene)|ensembl:ENSRNOT00000005143(transcript)|go:"GO:0001569"(branching involved in blood vessel morphogenesis)|go:"GO:0001666"(response to hypoxia)|go:"GO:0001667"(ameboidal-type cell migration)|go:"GO:0001764"(neuron migration)|go:"GO:0001822"(kidney development)|go:"GO:0001934"(positive regulation of protein phosphorylation)|go:"GO:0002064"(epithelial cell development)|go:"GO:0003281"(ventricular septum development)|go:"GO:0003779"(actin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005764"(lysosome)|go:"GO:0005768"(endosome)|go:"GO:0005769"(early endosome)|go:"GO:0005770"(late endosome)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0006955"(immune response)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0007204"(positive regulation of cytosolic calcium ion concentration)|go:"GO:0007281"(germ cell development)|go:"GO:0007420"(brain development)|go:"GO:0008038"(neuron recognition)|go:"GO:0008045"(motor neuron axon guidance)|go:"GO:0008354"(germ cell migration)|go:"GO:0009897"(external side of plasma membrane)|go:"GO:0009986"(cell surface)|go:"GO:0014823"(response to activity)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016477"(cell migration)|go:"GO:0016493"(C-C chemokine receptor activity)|go:"GO:0016494"(C-X-C chemokine receptor activity)|go:"GO:0019722"(calcium-mediated signaling)|go:"GO:0019957"(C-C chemokine binding)|go:"GO:0022008"(neurogenesis)|go:"GO:0022029"(telencephalon cell migration)|go:"GO:0030155"(regulation of cell adhesion)|go:"GO:0030334"(regulation of cell migration)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0030426"(growth cone)|go:"GO:0031252"(cell leading edge)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032027"(myosin light chain binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035470"(positive regulation of vascular wound healing)|go:"GO:0035690"|go:"GO:0035701"(hematopoietic stem cell migration)|go:"GO:0035904"(aorta development)|go:"GO:0038147"(C-X-C motif chemokine 12 receptor activity)|go:"GO:0038160"(CXCL12-activated CXCR4 signaling pathway)|go:"GO:0042098"(T cell proliferation)|go:"GO:0043067"(regulation of programmed cell death)|go:"GO:0043130"(ubiquitin binding)|go:"GO:0043217"(myelin maintenance)|go:"GO:0043278"(response to morphine)|go:"GO:0045446"(endothelial cell differentiation)|go:"GO:0048699"(generation of neurons)|go:"GO:0048714"(positive regulation of oligodendrocyte differentiation)|go:"GO:0050769"(positive regulation of neurogenesis)|go:"GO:0050792"(regulation of viral process)|go:"GO:0050920"(regulation of chemotaxis)|go:"GO:0050921"(positive regulation of chemotaxis)|go:"GO:0050965"(detection of temperature stimulus involved in sensory perception of pain)|go:"GO:0050966"(detection of mechanical stimulus involved in sensory perception of pain)|go:"GO:0051924"(regulation of calcium ion transport)|go:"GO:0060048"(cardiac muscle contraction)|go:"GO:0060326"(cell chemotaxis)|go:"GO:0061154"(endothelial tube morphogenesis)|go:"GO:0061351"(neural precursor cell proliferation)|go:"GO:0070374"(positive regulation of ERK1 and ERK2 cascade)|go:"GO:0071345"(cellular response to cytokine stimulus)|go:"GO:0090280"(positive regulation of calcium ion import)|go:"GO:0120162"(positive regulation of cold-induced thermogenesis)|go:"GO:1903861"(positive regulation of dendrite extension)|go:"GO:1905322"(positive regulation of mesenchymal stem cell migration)|go:"GO:1990478"(response to ultrasound)|go:"GO:2000448"(positive regulation of macrophage migration inhibitory factor signaling pathway)|interpro:IPR000276(GPCR, rhodopsin-like)|interpro:IPR000355(Chemokine receptor)|interpro:IPR001277(C-X-C chemokine receptor, type 4)|interpro:IPR017452(GPCR, rhodopsin-like superfamily)|interpro:IPR022726|mint:O08565|reactome:R-RNO-380108|reactome:R-RNO-418594|refseq:NP_071541.2	-	-	-	figure legend:st1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10116(rat-hippocampus)|taxid:10116(Rattus norvegicus hippocampal neurons)	-	2020/10/30	2020/10/30	rogid:DtE+ZXAZKdCMvUW5K+jXQ5bH07M10116	rogid:fF6oeliArkzJegdJf8Kwdcx/Zcc10116	rigid:zzsc1zNhBb5nwIRPeFpYOKgC3M8	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q5XIE8	uniprotkb:Q5BJS7	intact:EBI-15348306|ensembl:ENSRNOP00000023037	intact:EBI-26440307|ensembl:ENSRNOP00000074693	psi-mi:itm2b_rat(display_long)|uniprotkb:Itm2b(gene name)|psi-mi:Itm2b(display_short)|uniprotkb:Immature BRI2(gene name synonym)|uniprotkb:Transmembrane protein BRI(gene name synonym)	psi-mi:cpne9_rat(display_long)|uniprotkb:Cpne9(gene name)|psi-mi:Cpne9(display_short)|uniprotkb:Copine IX(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Martins et al. (2018)	imex:IM-28469|pubmed:29476059	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26440627|imex:IM-28469-5	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSRNOG00000016271(gene)|ensembl:ENSRNOT00000023037(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001540"(amyloid-beta binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0010008"(endosome membrane)|go:"GO:0030660"(Golgi-associated vesicle membrane)|go:"GO:0031301"(integral component of organelle membrane)|go:"GO:0042985"(negative regulation of amyloid precursor protein biosynthetic process)|interpro:IPR007084(BRICHOS)|interpro:IPR040145|mint:Q5XIE8|refseq:NP_001006964.1|rgd:620727	ensembl:ENSRNOG00000023077(gene)|ensembl:ENSRNOT00000091934(transcript)|go:"GO:0005544"(calcium-dependent phospholipid binding)|go:"GO:0005886"(plasma membrane)|go:"GO:0030154"(cell differentiation)|go:"GO:0046872"(metal ion binding)|go:"GO:0071277"(cellular response to calcium ion)|go:"GO:1903861"(positive regulation of dendrite extension)|interpro:IPR000008(C2 calcium-dependent membrane targeting)|interpro:IPR002035(von Willebrand factor, type A)|interpro:IPR010734(Copine)|interpro:IPR035892|interpro:IPR036465|interpro:IPR037768|mint:Q5BJS7|refseq:NP_001020153.1|rgd:1309212	-	-	-	figure legend:st1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10116(rat-hippocampus)|taxid:10116(Rattus norvegicus hippocampal neurons)	-	2020/10/30	2020/10/30	rogid:DtE+ZXAZKdCMvUW5K+jXQ5bH07M10116	rogid:72hC8AbQJXreiCHtZKt1I7rvyGA10116	rigid:zzsc1zNhBb5nwIRPeFpYOKgC3M8	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q5XIE8	uniprotkb:P63041	intact:EBI-15348306|ensembl:ENSRNOP00000023037	intact:EBI-1032858|uniprotkb:O09057|uniprotkb:O09142|uniprotkb:Q566D7|uniprotkb:Q64276|ensembl:ENSRNOP00000058432	psi-mi:itm2b_rat(display_long)|uniprotkb:Itm2b(gene name)|psi-mi:Itm2b(display_short)|uniprotkb:Immature BRI2(gene name synonym)|uniprotkb:Transmembrane protein BRI(gene name synonym)	psi-mi:cplx1_rat(display_long)|uniprotkb:Cplx1(gene name)|psi-mi:Cplx1(display_short)|uniprotkb:Complexin I(gene name synonym)|uniprotkb:Synaphin-2(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Martins et al. (2018)	imex:IM-28469|pubmed:29476059	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26440627|imex:IM-28469-5	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSRNOG00000016271(gene)|ensembl:ENSRNOT00000023037(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001540"(amyloid-beta binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0010008"(endosome membrane)|go:"GO:0030660"(Golgi-associated vesicle membrane)|go:"GO:0031301"(integral component of organelle membrane)|go:"GO:0042985"(negative regulation of amyloid precursor protein biosynthetic process)|interpro:IPR007084(BRICHOS)|interpro:IPR040145|mint:Q5XIE8|refseq:NP_001006964.1|rgd:620727	refseq:XP_006250633.1|rgd:70944|refseq:NP_074055.1|ensembl:ENSRNOG00000000060(gene)|ensembl:ENSRNOT00000061720(transcript)|go:"GO:0000149"(SNARE binding)|go:"GO:0005326"(neurotransmitter transmembrane transporter activity)|go:"GO:0005829"(cytosol)|go:"GO:0016079"(synaptic vesicle exocytosis)|go:"GO:0017075"(syntaxin-1 binding)|go:"GO:0030073"(insulin secretion)|go:"GO:0030425"(dendrite)|go:"GO:0031630"(regulation of synaptic vesicle fusion to presynaptic active zone membrane)|go:"GO:0032991"(protein-containing complex)|go:"GO:0043025"(neuronal cell body)|go:"GO:0031201"(SNARE complex)|go:"GO:0043195"(terminal bouton)|go:"GO:0043204"(perikaryon)|go:"GO:0044305"(calyx of Held)|go:"GO:0045202"(synapse)|go:"GO:0046928"(regulation of neurotransmitter secretion)|go:"GO:0070032"(synaptobrevin 2-SNAP-25-syntaxin-1a-complexin I complex)|go:"GO:0098685"(Schaffer collateral - CA1 synapse)|go:"GO:0098793"(presynapse)|go:"GO:0098794"(postsynapse)|go:"GO:0098967"(exocytic insertion of neurotransmitter receptor to postsynaptic membrane)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099003"(vesicle-mediated transport in synapse)|interpro:IPR008849(Synaphin)|mint:P63041|rcsb pdb:1KIL|rcsb pdb:5W5C|rcsb pdb:5W5D|reactome:R-RNO-181429|reactome:R-RNO-181430|reactome:R-RNO-210500|reactome:R-RNO-212676|reactome:R-RNO-264642|reactome:R-RNO-888590|dip:DIP-35502N	-	-	-	figure legend:st1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10116(rat-hippocampus)|taxid:10116(Rattus norvegicus hippocampal neurons)	-	2020/10/30	2020/10/30	rogid:DtE+ZXAZKdCMvUW5K+jXQ5bH07M10116	rogid:+52yE4o20ttkjnPNbfq7+jr/TuQ10116	rigid:zzsc1zNhBb5nwIRPeFpYOKgC3M8	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q5XIE8	uniprotkb:P31720	intact:EBI-15348306|ensembl:ENSRNOP00000023037	intact:EBI-26440275|ensembl:ENSRNOP00000017385|uniprotkb:Q5RJK1	psi-mi:itm2b_rat(display_long)|uniprotkb:Itm2b(gene name)|psi-mi:Itm2b(display_short)|uniprotkb:Immature BRI2(gene name synonym)|uniprotkb:Transmembrane protein BRI(gene name synonym)	psi-mi:c1qa_rat(display_long)|uniprotkb:C1qa(gene name)|psi-mi:C1qa(display_short)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Martins et al. (2018)	imex:IM-28469|pubmed:29476059	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26440627|imex:IM-28469-5	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSRNOG00000016271(gene)|ensembl:ENSRNOT00000023037(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001540"(amyloid-beta binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0010008"(endosome membrane)|go:"GO:0030660"(Golgi-associated vesicle membrane)|go:"GO:0031301"(integral component of organelle membrane)|go:"GO:0042985"(negative regulation of amyloid precursor protein biosynthetic process)|interpro:IPR007084(BRICHOS)|interpro:IPR040145|mint:Q5XIE8|refseq:NP_001006964.1|rgd:620727	go:"GO:0150062"(complement-mediated synapse pruning)|go:"GO:0150064"(vertebrate eye-specific patterning)|go:"GO:1901216"(positive regulation of neuron death)|interpro:IPR001073(Complement C1q protein)|interpro:IPR008160(Collagen triple helix repeat)|interpro:IPR008983(Tumour necrosis factor-like)|interpro:IPR037572|mint:P31720|reactome:R-RNO-166663|reactome:R-RNO-173623|reactome:R-RNO-977606|go:"GO:0098883"(synapse pruning)|ensembl:ENSRNOG00000012807(gene)|ensembl:ENSRNOT00000017385(transcript)|go:"GO:0001774"(microglial cell activation)|go:"GO:0005576"(extracellular region)|go:"GO:0005581"(collagen trimer)|go:"GO:0006958"(complement activation, classical pathway)|go:"GO:0007568"(aging)|go:"GO:0010039"(response to iron ion)|go:"GO:0016322"(neuron remodeling)|go:"GO:0045087"(innate immune response)|go:"GO:0045202"(synapse)|go:"GO:0048143"(astrocyte activation)|go:"GO:0050808"(synapse organization)|go:"GO:0098794"(postsynapse)|refseq:NP_001008515.1|rgd:1306716	-	-	-	figure legend:st1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10116(rat-hippocampus)|taxid:10116(Rattus norvegicus hippocampal neurons)	-	2020/10/30	2020/10/30	rogid:DtE+ZXAZKdCMvUW5K+jXQ5bH07M10116	rogid:ibzy+ZZuRwoqnLoqK5Sd+JbIA5w10116	rigid:zzsc1zNhBb5nwIRPeFpYOKgC3M8	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q5XIE8	uniprotkb:Q63092	intact:EBI-15348306|ensembl:ENSRNOP00000023037	intact:EBI-26440258	psi-mi:itm2b_rat(display_long)|uniprotkb:Itm2b(gene name)|psi-mi:Itm2b(display_short)|uniprotkb:Immature BRI2(gene name synonym)|uniprotkb:Transmembrane protein BRI(gene name synonym)	psi-mi:camkv_rat(display_long)|uniprotkb:Camkv(gene name)|psi-mi:Camkv(display_short)|uniprotkb:1G5(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Martins et al. (2018)	imex:IM-28469|pubmed:29476059	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26440627|imex:IM-28469-5	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSRNOG00000016271(gene)|ensembl:ENSRNOT00000023037(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001540"(amyloid-beta binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0010008"(endosome membrane)|go:"GO:0030660"(Golgi-associated vesicle membrane)|go:"GO:0031301"(integral component of organelle membrane)|go:"GO:0042985"(negative regulation of amyloid precursor protein biosynthetic process)|interpro:IPR007084(BRICHOS)|interpro:IPR040145|mint:Q5XIE8|refseq:NP_001006964.1|rgd:620727	go:"GO:0004683"(calmodulin-dependent protein kinase activity)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005886"(plasma membrane)|go:"GO:0018105"(peptidyl-serine phosphorylation)|go:"GO:0030659"(cytoplasmic vesicle membrane)|go:"GO:0098794"(postsynapse)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099159"(regulation of modification of postsynaptic structure)|mint:Q63092|refseq:NP_076490.1|interpro:IPR011009(Protein kinase-like)|interpro:IPR000719(Protein kinase, core)|rgd:621488	-	-	-	figure legend:st1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10116(rat-hippocampus)|taxid:10116(Rattus norvegicus hippocampal neurons)	-	2020/10/30	2020/10/30	rogid:DtE+ZXAZKdCMvUW5K+jXQ5bH07M10116	rogid:0yUMnPSupg/4zGaNDJHQZ3YhEWw10116	rigid:zzsc1zNhBb5nwIRPeFpYOKgC3M8	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q5XIE8	uniprotkb:Q05175	intact:EBI-15348306|ensembl:ENSRNOP00000023037	intact:EBI-26440237	psi-mi:itm2b_rat(display_long)|uniprotkb:Itm2b(gene name)|psi-mi:Itm2b(display_short)|uniprotkb:Immature BRI2(gene name synonym)|uniprotkb:Transmembrane protein BRI(gene name synonym)	psi-mi:basp1_rat(display_long)|uniprotkb:Basp1(gene name)|psi-mi:Basp1(display_short)|uniprotkb:Nap22(gene name synonym)|uniprotkb:22 kDa neuronal tissue-enriched acidic protein(gene name synonym)|uniprotkb:Neuronal axonal membrane protein NAP-22(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Martins et al. (2018)	imex:IM-28469|pubmed:29476059	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26440627|imex:IM-28469-5	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSRNOG00000016271(gene)|ensembl:ENSRNOT00000023037(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001540"(amyloid-beta binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0010008"(endosome membrane)|go:"GO:0030660"(Golgi-associated vesicle membrane)|go:"GO:0031301"(integral component of organelle membrane)|go:"GO:0042985"(negative regulation of amyloid precursor protein biosynthetic process)|interpro:IPR007084(BRICHOS)|interpro:IPR040145|mint:Q5XIE8|refseq:NP_001006964.1|rgd:620727	go:"GO:0000785"(chromatin)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0016363"(nuclear matrix)|go:"GO:0016605"(PML body)|go:"GO:0016607"(nuclear speck)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030426"(growth cone)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0072112"(glomerular visceral epithelial cell differentiation)|reactome:R-RNO-9035034|mint:Q05175|refseq:NP_071636.1|interpro:IPR008408(Brain acid soluble protein 1)|rgd:621491	-	-	-	figure legend:st1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10116(rat-hippocampus)|taxid:10116(Rattus norvegicus hippocampal neurons)	-	2020/10/30	2020/10/30	rogid:DtE+ZXAZKdCMvUW5K+jXQ5bH07M10116	rogid:mKUbCMgO49o/m+yaj1knqjHcgKg10116	rigid:zzsc1zNhBb5nwIRPeFpYOKgC3M8	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q5XIE8	uniprotkb:P85969	intact:EBI-15348306|ensembl:ENSRNOP00000023037	intact:EBI-8848583|uniprotkb:A6K7C6	psi-mi:itm2b_rat(display_long)|uniprotkb:Itm2b(gene name)|psi-mi:Itm2b(display_short)|uniprotkb:Immature BRI2(gene name synonym)|uniprotkb:Transmembrane protein BRI(gene name synonym)	psi-mi:snab_rat(display_long)|uniprotkb:Napb(gene name)|psi-mi:Napb(display_short)|uniprotkb:Snapb(gene name synonym)|uniprotkb:N-ethylmaleimide-sensitive factor attachment protein beta(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Martins et al. (2018)	imex:IM-28469|pubmed:29476059	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26440627|imex:IM-28469-5	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSRNOG00000016271(gene)|ensembl:ENSRNOT00000023037(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001540"(amyloid-beta binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0010008"(endosome membrane)|go:"GO:0030660"(Golgi-associated vesicle membrane)|go:"GO:0031301"(integral component of organelle membrane)|go:"GO:0042985"(negative regulation of amyloid precursor protein biosynthetic process)|interpro:IPR007084(BRICHOS)|interpro:IPR040145|mint:Q5XIE8|refseq:NP_001006964.1|rgd:620727	mint:P85969|interpro:IPR000744(NSF attachment protein)|interpro:IPR011990(Tetratricopeptide-like helical)|rgd:1589649|go:"GO:0000149"(SNARE binding)|go:"GO:0002090"(regulation of receptor internalization)|go:"GO:0005483"(soluble NSF attachment protein activity)|go:"GO:0005774"(vacuolar membrane)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0010807"(regulation of synaptic vesicle priming)|go:"GO:0019905"(syntaxin binding)|go:"GO:0031201"(SNARE complex)|go:"GO:0032984"(protein-containing complex disassembly)|go:"GO:0035249"(synaptic transmission, glutamatergic)|go:"GO:0035494"(SNARE complex disassembly)|go:"GO:0043462"(regulation of ATP-dependent activity)|go:"GO:0070044"(synaptobrevin 2-SNAP-25-syntaxin-1a complex)|go:"GO:0098793"(presynapse)|go:"GO:0098794"(postsynapse)|go:"GO:0098978"(glutamatergic synapse)|reactome:R-RNO-204005|reactome:R-RNO-6807878|reactome:R-RNO-6811434|reactome:R-RNO-6811438|reactome:R-RNO-6811440	-	-	-	figure legend:st1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10116(rat-hippocampus)|taxid:10116(Rattus norvegicus hippocampal neurons)	-	2020/10/30	2020/10/30	rogid:DtE+ZXAZKdCMvUW5K+jXQ5bH07M10116	rogid:4aXMgCO9W3itdB0tv3uo251Qye010116	rigid:zzsc1zNhBb5nwIRPeFpYOKgC3M8	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q5XIE8	uniprotkb:Q05764	intact:EBI-15348306|ensembl:ENSRNOP00000023037	intact:EBI-26440200	psi-mi:itm2b_rat(display_long)|uniprotkb:Itm2b(gene name)|psi-mi:Itm2b(display_short)|uniprotkb:Immature BRI2(gene name synonym)|uniprotkb:Transmembrane protein BRI(gene name synonym)	psi-mi:addb_rat(display_long)|uniprotkb:Add2(gene name)|psi-mi:Add2(display_short)|uniprotkb:Adducin-63(gene name synonym)|uniprotkb:Erythrocyte adducin subunit beta(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Martins et al. (2018)	imex:IM-28469|pubmed:29476059	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26440627|imex:IM-28469-5	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSRNOG00000016271(gene)|ensembl:ENSRNOT00000023037(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001540"(amyloid-beta binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0010008"(endosome membrane)|go:"GO:0030660"(Golgi-associated vesicle membrane)|go:"GO:0031301"(integral component of organelle membrane)|go:"GO:0042985"(negative regulation of amyloid precursor protein biosynthetic process)|interpro:IPR007084(BRICHOS)|interpro:IPR040145|mint:Q5XIE8|refseq:NP_001006964.1|rgd:620727	go:"GO:0003779"(actin binding)|go:"GO:0051016"(barbed-end actin filament capping)|go:"GO:0051017"(actin filament bundle assembly)|go:"GO:0065003"(protein-containing complex assembly)|go:"GO:0098794"(postsynapse)|go:"GO:0098978"(glutamatergic synapse)|reactome:R-RNO-5223345|go:"GO:0005200"(structural constituent of cytoskeleton)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005886"(plasma membrane)|go:"GO:0006811"(ion transport)|go:"GO:0007416"(synapse assembly)|go:"GO:0008290"(F-actin capping protein complex)|go:"GO:0014069"(postsynaptic density)|go:"GO:0016020"(membrane)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030097"(hemopoiesis)|go:"GO:0030507"(spectrin binding)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0032092"(positive regulation of protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0044853"(plasma membrane raft)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0050900"(leukocyte migration)|go:"GO:0050901"(leukocyte tethering or rolling)|go:"GO:0051015"(actin filament binding)|mint:Q05764|refseq:NP_001103350.1|refseq:NP_036623.1|interpro:IPR027773|interpro:IPR001303(Class II aldolase/adducin, N-terminal)|interpro:IPR036409|rgd:2042	-	-	-	figure legend:st1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10116(rat-hippocampus)|taxid:10116(Rattus norvegicus hippocampal neurons)	-	2020/10/30	2020/10/30	rogid:DtE+ZXAZKdCMvUW5K+jXQ5bH07M10116	rogid:5HrbM5p6kWqODF7VFP6P/j+S9MQ10116	rigid:zzsc1zNhBb5nwIRPeFpYOKgC3M8	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q5XIE8	uniprotkb:P47860	intact:EBI-15348306|ensembl:ENSRNOP00000023037	intact:EBI-349363|uniprotkb:Q5HZX8	psi-mi:itm2b_rat(display_long)|uniprotkb:Itm2b(gene name)|psi-mi:Itm2b(display_short)|uniprotkb:Immature BRI2(gene name synonym)|uniprotkb:Transmembrane protein BRI(gene name synonym)	psi-mi:pfkap_rat(display_long)|uniprotkb:Pfkp(gene name)|psi-mi:Pfkp(display_short)|uniprotkb:Pfkc(gene name synonym)|uniprotkb:Phosphohexokinase(gene name synonym)|uniprotkb:Phosphofructo-1-kinase isozyme C(gene name synonym)|uniprotkb:6-phosphofructokinase type C(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Martins et al. (2018)	imex:IM-28469|pubmed:29476059	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26440627|imex:IM-28469-5	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSRNOG00000016271(gene)|ensembl:ENSRNOT00000023037(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001540"(amyloid-beta binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0010008"(endosome membrane)|go:"GO:0030660"(Golgi-associated vesicle membrane)|go:"GO:0031301"(integral component of organelle membrane)|go:"GO:0042985"(negative regulation of amyloid precursor protein biosynthetic process)|interpro:IPR007084(BRICHOS)|interpro:IPR040145|mint:Q5XIE8|refseq:NP_001006964.1|rgd:620727	rgd:61893|refseq:NP_996729.1|interpro:IPR009161(6-phosphofructokinase, eukaryotic type)|interpro:IPR022953|interpro:IPR015912(Phosphofructokinase, conserved site)|interpro:IPR000023(Phosphofructokinase)|go:"GO:0003872"(6-phosphofructokinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005945"(6-phosphofructokinase complex)|go:"GO:0006002"(fructose 6-phosphate metabolic process)|go:"GO:0006096"(glycolytic process)|go:"GO:0016020"(membrane)|go:"GO:0016208"(AMP binding)|go:"GO:0030388"(fructose 1,6-bisphosphate metabolic process)|go:"GO:0042802"(identical protein binding)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0046872"(metal ion binding)|go:"GO:0048029"(monosaccharide binding)|go:"GO:0061621"(canonical glycolysis)|go:"GO:0070095"(fructose-6-phosphate binding)|go:"GO:1990830"(cellular response to leukemia inhibitory factor)|reactome:R-RNO-70171|mint:P47860|interpro:IPR035966|interpro:IPR041914	-	-	-	figure legend:st1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10116(rat-hippocampus)|taxid:10116(Rattus norvegicus hippocampal neurons)	-	2020/10/30	2020/10/30	rogid:DtE+ZXAZKdCMvUW5K+jXQ5bH07M10116	rogid:2J63wKACzINJ2T1SvK7fKCdhu0410116	rigid:zzsc1zNhBb5nwIRPeFpYOKgC3M8	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q5XIE8	uniprotkb:P47858	intact:EBI-15348306|ensembl:ENSRNOP00000023037	intact:EBI-349356|uniprotkb:Q63736	psi-mi:itm2b_rat(display_long)|uniprotkb:Itm2b(gene name)|psi-mi:Itm2b(display_short)|uniprotkb:Immature BRI2(gene name synonym)|uniprotkb:Transmembrane protein BRI(gene name synonym)	psi-mi:pfkam_rat(display_long)|uniprotkb:Pfkm(gene name)|psi-mi:Pfkm(display_short)|uniprotkb:Pfk-m(gene name synonym)|uniprotkb:Phosphohexokinase(gene name synonym)|uniprotkb:Phosphofructo-1-kinase isozyme A(gene name synonym)|uniprotkb:6-phosphofructokinase type A(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Martins et al. (2018)	imex:IM-28469|pubmed:29476059	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26440627|imex:IM-28469-5	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSRNOG00000016271(gene)|ensembl:ENSRNOT00000023037(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001540"(amyloid-beta binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0010008"(endosome membrane)|go:"GO:0030660"(Golgi-associated vesicle membrane)|go:"GO:0031301"(integral component of organelle membrane)|go:"GO:0042985"(negative regulation of amyloid precursor protein biosynthetic process)|interpro:IPR007084(BRICHOS)|interpro:IPR040145|mint:Q5XIE8|refseq:NP_001006964.1|rgd:620727	rgd:68419|refseq:NP_113903.1|interpro:IPR009161(6-phosphofructokinase, eukaryotic type)|interpro:IPR022953|interpro:IPR015912(Phosphofructokinase, conserved site)|interpro:IPR000023(Phosphofructokinase)|go:"GO:0001678"(cellular glucose homeostasis)|go:"GO:0003872"(6-phosphofructokinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0005945"(6-phosphofructokinase complex)|go:"GO:0005980"(glycogen catabolic process)|go:"GO:0006002"(fructose 6-phosphate metabolic process)|go:"GO:0006096"(glycolytic process)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008443"(phosphofructokinase activity)|go:"GO:0016020"(membrane)|go:"GO:0016208"(AMP binding)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0019900"(kinase binding)|go:"GO:0030246"(carbohydrate binding)|go:"GO:0030388"(fructose 1,6-bisphosphate metabolic process)|go:"GO:0032024"(positive regulation of insulin secretion)|go:"GO:0042593"(glucose homeostasis)|go:"GO:0042802"(identical protein binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046716"(muscle cell cellular homeostasis)|go:"GO:0046872"(metal ion binding)|go:"GO:0048029"(monosaccharide binding)|go:"GO:0061615"(glycolytic process through fructose-6-phosphate)|go:"GO:0061621"(canonical glycolysis)|go:"GO:0070061"(fructose binding)|go:"GO:0070095"(fructose-6-phosphate binding)|go:"GO:0093001"(glycolysis from storage polysaccharide through glucose-1-phosphate)|go:"GO:0097228"(sperm principal piece)|reactome:R-RNO-70171|mint:P47858|interpro:IPR035966|interpro:IPR041914	-	-	-	figure legend:st1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10116(rat-hippocampus)|taxid:10116(Rattus norvegicus hippocampal neurons)	-	2020/10/30	2020/10/30	rogid:DtE+ZXAZKdCMvUW5K+jXQ5bH07M10116	rogid:y1QKLAwU/FRyflZI8xnOKZsKOvc10116	rigid:zzsc1zNhBb5nwIRPeFpYOKgC3M8	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q5XIE8	uniprotkb:Q7TNJ2	intact:EBI-15348306|ensembl:ENSRNOP00000023037	intact:EBI-26440141	psi-mi:itm2b_rat(display_long)|uniprotkb:Itm2b(gene name)|psi-mi:Itm2b(display_short)|uniprotkb:Immature BRI2(gene name synonym)|uniprotkb:Transmembrane protein BRI(gene name synonym)	psi-mi:abca7_rat(display_long)|uniprotkb:Abca7(gene name)|psi-mi:Abca7(display_short)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Martins et al. (2018)	imex:IM-28469|pubmed:29476059	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26440627|imex:IM-28469-5	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSRNOG00000016271(gene)|ensembl:ENSRNOT00000023037(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001540"(amyloid-beta binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0010008"(endosome membrane)|go:"GO:0030660"(Golgi-associated vesicle membrane)|go:"GO:0031301"(integral component of organelle membrane)|go:"GO:0042985"(negative regulation of amyloid precursor protein biosynthetic process)|interpro:IPR007084(BRICHOS)|interpro:IPR040145|mint:Q5XIE8|refseq:NP_001006964.1|rgd:620727	go:"GO:0000139"(Golgi membrane)|go:"GO:0001891"(phagocytic cup)|go:"GO:0005319"(lipid transporter activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005548"(phospholipid transporter activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0006869"(lipid transport)|go:"GO:0006909"(phagocytosis)|go:"GO:0007613"(memory)|go:"GO:0008542"(visual learning)|go:"GO:0009986"(cell surface)|go:"GO:1900223"(positive regulation of amyloid-beta clearance)|go:"GO:1901076"(positive regulation of engulfment of apoptotic cell)|go:"GO:1902430"(negative regulation of amyloid-beta formation)|go:"GO:1902991"(regulation of amyloid precursor protein catabolic process)|go:"GO:1902995"(positive regulation of phospholipid efflux)|go:"GO:1903898"(negative regulation of PERK-mediated unfolded protein response)|go:"GO:2000010"(positive regulation of protein localization to cell surface)|reactome:R-RNO-1369062|go:"GO:0031901"(early endosome membrane)|go:"GO:0032587"(ruffle membrane)|go:"GO:0033344"(cholesterol efflux)|go:"GO:0033700"(phospholipid efflux)|go:"GO:0034188"(apolipoprotein A-I receptor activity)|go:"GO:0034205"(amyloid-beta formation)|go:"GO:0034380"(high-density lipoprotein particle assembly)|go:"GO:0034504"(protein localization to nucleus)|go:"GO:0038027"(apolipoprotein A-I-mediated signaling pathway)|go:"GO:0042626"(ATPase-coupled transmembrane transporter activity)|go:"GO:0042985"(negative regulation of amyloid precursor protein biosynthetic process)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0043409"(negative regulation of MAPK cascade)|go:"GO:0044857"(plasma membrane raft organization)|go:"GO:0045332"(phospholipid translocation)|go:"GO:0045806"(negative regulation of endocytosis)|go:"GO:0050766"(positive regulation of phagocytosis)|go:"GO:0070374"(positive regulation of ERK1 and ERK2 cascade)|go:"GO:0090554"(phosphatidylcholine floppase activity)|go:"GO:0090556"(phosphatidylserine floppase activity)|go:"GO:0097386"(glial cell projection)|go:"GO:0140328"(floppase activity)|go:"GO:0150094"(amyloid-beta clearance by cellular catabolic process)|go:"GO:0010875"(positive regulation of cholesterol efflux)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0018149"(peptide cross-linking)|go:"GO:0019216"(regulation of lipid metabolic process)|mint:Q7TNJ2|refseq:NP_997481.1|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR003439(ABC transporter-like)|interpro:IPR017871|interpro:IPR026082|interpro:IPR030369|interpro:IPR027417|rgd:1303134	-	-	-	figure legend:st1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10116(rat-hippocampus)|taxid:10116(Rattus norvegicus hippocampal neurons)	-	2020/10/30	2020/10/30	rogid:DtE+ZXAZKdCMvUW5K+jXQ5bH07M10116	rogid:MjbcoOjZFqs3FZDX/F0FPeS0YiA10116	rigid:zzsc1zNhBb5nwIRPeFpYOKgC3M8	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q5XIE8	uniprotkb:P21571	intact:EBI-15348306|ensembl:ENSRNOP00000023037	intact:EBI-26440110|ensembl:ENSRNOP00000002116	psi-mi:itm2b_rat(display_long)|uniprotkb:Itm2b(gene name)|psi-mi:Itm2b(display_short)|uniprotkb:Immature BRI2(gene name synonym)|uniprotkb:Transmembrane protein BRI(gene name synonym)	psi-mi:atp5j_rat(display_long)|uniprotkb:Atp5pf(gene name)|psi-mi:Atp5pf(display_short)|uniprotkb:Atp5j(gene name synonym)|uniprotkb:ATP synthase peripheral stalk subunit F6(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Martins et al. (2018)	imex:IM-28469|pubmed:29476059	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26440627|imex:IM-28469-5	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSRNOG00000016271(gene)|ensembl:ENSRNOT00000023037(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001540"(amyloid-beta binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0010008"(endosome membrane)|go:"GO:0030660"(Golgi-associated vesicle membrane)|go:"GO:0031301"(integral component of organelle membrane)|go:"GO:0042985"(negative regulation of amyloid precursor protein biosynthetic process)|interpro:IPR007084(BRICHOS)|interpro:IPR040145|mint:Q5XIE8|refseq:NP_001006964.1|rgd:620727	go:"GO:0046034"(ATP metabolic process)|go:"GO:0046933"(proton-transporting ATP synthase activity, rotational mechanism)|go:"GO:1900139"(negative regulation of arachidonic acid secretion)|interpro:IPR008387(ATPase, F0 complex, subunit F6, mitochondrial)|interpro:IPR036204|mint:P21571|reactome:R-RNO-163210|reactome:R-RNO-8949613|ensembl:ENSRNOG00000001551(gene)|ensembl:ENSRNOT00000002116(transcript)|go:"GO:0000276"("mitochondrial proton-transporting ATP synthase complex, coupling factor F(o)")|go:"GO:0005615"(extracellular space)|go:"GO:0005739"(mitochondrion)|go:"GO:0005753"(mitochondrial proton-transporting ATP synthase complex)|go:"GO:0009986"(cell surface)|go:"GO:0010460"(positive regulation of heart rate)|go:"GO:0014850"(response to muscle activity)|go:"GO:0032307"(negative regulation of prostaglandin secretion)|go:"GO:0042776"(mitochondrial ATP synthesis coupled proton transport)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045777"(positive regulation of blood pressure)|refseq:NP_446054.1|refseq:XP_008766824.1|refseq:XP_008766825.1|refseq:XP_017453574.1|refseq:XP_017453575.1|rgd:621376	-	-	-	figure legend:st1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10116(rat-hippocampus)|taxid:10116(Rattus norvegicus hippocampal neurons)	-	2020/10/30	2020/10/30	rogid:DtE+ZXAZKdCMvUW5K+jXQ5bH07M10116	rogid:dpIfBUKgaLmFVpGqfp258EWzqMQ10116	rigid:zzsc1zNhBb5nwIRPeFpYOKgC3M8	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q5XIE8	uniprotkb:P35434	intact:EBI-15348306|ensembl:ENSRNOP00000023037	intact:EBI-917347	psi-mi:itm2b_rat(display_long)|uniprotkb:Itm2b(gene name)|psi-mi:Itm2b(display_short)|uniprotkb:Immature BRI2(gene name synonym)|uniprotkb:Transmembrane protein BRI(gene name synonym)	psi-mi:atpd_rat(display_long)|uniprotkb:ATP synthase F1 subunit delta(gene name synonym)|uniprotkb:Atp5f1d(gene name)|psi-mi:Atp5f1d(display_short)|uniprotkb:Atp5d(gene name synonym)|uniprotkb:F-ATPase delta subunit(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Martins et al. (2018)	imex:IM-28469|pubmed:29476059	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26440627|imex:IM-28469-5	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSRNOG00000016271(gene)|ensembl:ENSRNOT00000023037(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001540"(amyloid-beta binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0010008"(endosome membrane)|go:"GO:0030660"(Golgi-associated vesicle membrane)|go:"GO:0031301"(integral component of organelle membrane)|go:"GO:0042985"(negative regulation of amyloid precursor protein biosynthetic process)|interpro:IPR007084(BRICHOS)|interpro:IPR040145|mint:Q5XIE8|refseq:NP_001006964.1|rgd:620727	rgd:621372|refseq:NP_620806.1|interpro:IPR001469(ATPase, F1 complex, delta/epsilon subunit)|interpro:IPR020546|mint:P35434|interpro:IPR036771|interpro:IPR036794|go:"GO:0000275"("mitochondrial proton-transporting ATP synthase complex, catalytic sector F(1)")|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005753"(mitochondrial proton-transporting ATP synthase complex)|go:"GO:0006754"(ATP biosynthetic process)|go:"GO:0009060"(aerobic respiration)|go:"GO:0015986"(ATP synthesis coupled proton transport)|go:"GO:0033615"(mitochondrial proton-transporting ATP synthase complex assembly)|go:"GO:0042776"(mitochondrial ATP synthesis coupled proton transport)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045259"(proton-transporting ATP synthase complex)|go:"GO:0045261"("proton-transporting ATP synthase complex, catalytic core F(1)")|go:"GO:0046034"(ATP metabolic process)|go:"GO:0046933"(proton-transporting ATP synthase activity, rotational mechanism)|go:"GO:1904638"(response to resveratrol)|reactome:R-RNO-163210|reactome:R-RNO-8949613	-	-	-	figure legend:st1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10116(rat-hippocampus)|taxid:10116(Rattus norvegicus hippocampal neurons)	-	2020/10/30	2020/10/30	rogid:DtE+ZXAZKdCMvUW5K+jXQ5bH07M10116	rogid:Lop70nPmqktZ1JdbvWEXr7EgNnk10116	rigid:zzsc1zNhBb5nwIRPeFpYOKgC3M8	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q5XIE8	uniprotkb:P31399	intact:EBI-15348306|ensembl:ENSRNOP00000023037	intact:EBI-917233|ensembl:ENSRNOP00000004836	psi-mi:itm2b_rat(display_long)|uniprotkb:Itm2b(gene name)|psi-mi:Itm2b(display_short)|uniprotkb:Immature BRI2(gene name synonym)|uniprotkb:Transmembrane protein BRI(gene name synonym)	psi-mi:atp5h_rat(display_long)|uniprotkb:Atp5pd(gene name)|psi-mi:Atp5pd(display_short)|uniprotkb:ATP synthase peripheral stalk subunit d(gene name synonym)|uniprotkb:Atp5h(gene name synonym)|uniprotkb:Atp5jd(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Martins et al. (2018)	imex:IM-28469|pubmed:29476059	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26440627|imex:IM-28469-5	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSRNOG00000016271(gene)|ensembl:ENSRNOT00000023037(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001540"(amyloid-beta binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0010008"(endosome membrane)|go:"GO:0030660"(Golgi-associated vesicle membrane)|go:"GO:0031301"(integral component of organelle membrane)|go:"GO:0042985"(negative regulation of amyloid precursor protein biosynthetic process)|interpro:IPR007084(BRICHOS)|interpro:IPR040145|mint:Q5XIE8|refseq:NP_001006964.1|rgd:620727	rgd:620083|refseq:NP_062256.1|ensembl:ENSRNOG00000003626(gene)|ensembl:ENSRNOT00000004836(transcript)|go:"GO:0000274"(mitochondrial proton-transporting ATP synthase, stator stalk)|go:"GO:0000276"("mitochondrial proton-transporting ATP synthase complex, coupling factor F(o)")|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005753"(mitochondrial proton-transporting ATP synthase complex)|go:"GO:0015078"(proton transmembrane transporter activity)|go:"GO:0015986"(ATP synthesis coupled proton transport)|go:"GO:0042776"(mitochondrial ATP synthesis coupled proton transport)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0046034"(ATP metabolic process)|go:"GO:1901653"(cellular response to peptide)|interpro:IPR008689(ATPase, F0 complex, subunit D, mitochondrial)|interpro:IPR036228|mint:P31399|reactome:R-RNO-163210|reactome:R-RNO-8949613	-	-	-	figure legend:st1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10116(rat-hippocampus)|taxid:10116(Rattus norvegicus hippocampal neurons)	-	2020/10/30	2020/10/30	rogid:DtE+ZXAZKdCMvUW5K+jXQ5bH07M10116	rogid:a1M9m03ICQoQPzfrjdot96mD0X410116	rigid:zzsc1zNhBb5nwIRPeFpYOKgC3M8	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q5XIE8	uniprotkb:P10719	intact:EBI-15348306|ensembl:ENSRNOP00000023037	intact:EBI-916266|uniprotkb:Q499W0	psi-mi:itm2b_rat(display_long)|uniprotkb:Itm2b(gene name)|psi-mi:Itm2b(display_short)|uniprotkb:Immature BRI2(gene name synonym)|uniprotkb:Transmembrane protein BRI(gene name synonym)	psi-mi:atpb_rat(display_long)|uniprotkb:Atp5f1b(gene name)|psi-mi:Atp5f1b(display_short)|uniprotkb:ATP synthase F1 subunit beta(gene name synonym)|uniprotkb:Atp5b(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Martins et al. (2018)	imex:IM-28469|pubmed:29476059	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26440627|imex:IM-28469-5	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSRNOG00000016271(gene)|ensembl:ENSRNOT00000023037(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001540"(amyloid-beta binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0010008"(endosome membrane)|go:"GO:0030660"(Golgi-associated vesicle membrane)|go:"GO:0031301"(integral component of organelle membrane)|go:"GO:0042985"(negative regulation of amyloid precursor protein biosynthetic process)|interpro:IPR007084(BRICHOS)|interpro:IPR040145|mint:Q5XIE8|refseq:NP_001006964.1|rgd:620727	rgd:621368|refseq:NP_599191.1|interpro:IPR020003|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR004100(ATPase, F1/V1/A1 complex, alpha/beta subunit, N-terminal)|interpro:IPR000194(ATPase, F1/V1/A1 complex, alpha/beta subunit, nucleotide-binding)|interpro:IPR024034|interpro:IPR005722(ATPase, F1 complex, beta subunit)|go:"GO:0000275"("mitochondrial proton-transporting ATP synthase complex, catalytic sector F(1)")|go:"GO:0001525"(angiogenesis)|go:"GO:0001889"(liver development)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005753"(mitochondrial proton-transporting ATP synthase complex)|go:"GO:0005886"(plasma membrane)|go:"GO:0006629"(lipid metabolic process)|go:"GO:0006754"(ATP biosynthetic process)|go:"GO:0006898"(receptor-mediated endocytosis)|go:"GO:0006933"(negative regulation of cell adhesion involved in substrate-bound cell migration)|go:"GO:0009631"(cold acclimation)|go:"GO:0009986"(cell surface)|go:"GO:0010042"(response to manganese ion)|go:"GO:0016020"(membrane)|go:"GO:0030228"(lipoprotein particle receptor activity)|go:"GO:0031966"(mitochondrial membrane)|go:"GO:0042288"(MHC class I protein binding)|go:"GO:0042645"(mitochondrial nucleoid)|go:"GO:0042776"(mitochondrial ATP synthesis coupled proton transport)|go:"GO:0043531"(ADP binding)|go:"GO:0043532"(angiostatin binding)|go:"GO:0043536"(positive regulation of blood vessel endothelial cell migration)|go:"GO:0045121"(membrane raft)|go:"GO:0045259"(proton-transporting ATP synthase complex)|go:"GO:0045261"("proton-transporting ATP synthase complex, catalytic core F(1)")|go:"GO:0046034"(ATP metabolic process)|go:"GO:0046933"(proton-transporting ATP synthase activity, rotational mechanism)|go:"GO:0046961"(proton-transporting ATPase activity, rotational mechanism)|go:"GO:0051453"(regulation of intracellular pH)|go:"GO:0098761"(cellular response to interleukin-7)|go:"GO:1901653"(cellular response to peptide)|go:"GO:1902600"(proton transmembrane transport)|go:"GO:1904643"(response to curcumin)|go:"GO:1905242"(response to 3,3',5-triiodo-L-thyronine)|rcsb pdb:1MAB|rcsb pdb:2F43|reactome:R-RNO-1268020|reactome:R-RNO-163210|reactome:R-RNO-8949613|interpro:IPR027417|mint:P10719|interpro:IPR036121	-	-	-	figure legend:st1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10116(rat-hippocampus)|taxid:10116(Rattus norvegicus hippocampal neurons)	-	2020/10/30	2020/10/30	rogid:DtE+ZXAZKdCMvUW5K+jXQ5bH07M10116	rogid:K1RREEkTYSnEnU2leNpq3SCa3wc10116	rigid:zzsc1zNhBb5nwIRPeFpYOKgC3M8	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q5XIE8	uniprotkb:P21396	intact:EBI-15348306|ensembl:ENSRNOP00000023037	intact:EBI-26440085|uniprotkb:Q63817	psi-mi:itm2b_rat(display_long)|uniprotkb:Itm2b(gene name)|psi-mi:Itm2b(display_short)|uniprotkb:Immature BRI2(gene name synonym)|uniprotkb:Transmembrane protein BRI(gene name synonym)	psi-mi:aofa_rat(display_long)|uniprotkb:Maoa(gene name)|psi-mi:Maoa(display_short)|uniprotkb:Monoamine oxidase type A(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Martins et al. (2018)	imex:IM-28469|pubmed:29476059	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26440627|imex:IM-28469-5	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSRNOG00000016271(gene)|ensembl:ENSRNOT00000023037(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001540"(amyloid-beta binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0010008"(endosome membrane)|go:"GO:0030660"(Golgi-associated vesicle membrane)|go:"GO:0031301"(integral component of organelle membrane)|go:"GO:0042985"(negative regulation of amyloid precursor protein biosynthetic process)|interpro:IPR007084(BRICHOS)|interpro:IPR040145|mint:Q5XIE8|refseq:NP_001006964.1|rgd:620727	go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0008131"(primary amine oxidase activity)|go:"GO:0009967"(positive regulation of signal transduction)|go:"GO:0016021"(integral component of membrane)|go:"GO:0042135"(neurotransmitter catabolic process)|go:"GO:0042428"(serotonin metabolic process)|go:"GO:0042443"(phenylethylamine metabolic process)|go:"GO:0050660"(flavin adenine dinucleotide binding)|go:"GO:0051378"(serotonin binding)|go:"GO:0097621"(monoamine oxidase activity)|rcsb pdb:1O5W|reactome:R-RNO-141333|reactome:R-RNO-181430|go:"GO:0042420"(dopamine catabolic process)|go:"GO:0042424"(catecholamine catabolic process)|reactome:R-RNO-379397|reactome:R-RNO-379398|reactome:R-RNO-380612|mint:P21396|interpro:IPR002937(Amine oxidase)|interpro:IPR036188|interpro:IPR001613(Flavin-containing amine oxidase)|rgd:61898	-	-	-	figure legend:st1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10116(rat-hippocampus)|taxid:10116(Rattus norvegicus hippocampal neurons)	-	2020/10/30	2020/10/30	rogid:DtE+ZXAZKdCMvUW5K+jXQ5bH07M10116	rogid:dR9NgusDpgYlTW0sCO/MHI3xvtQ10116	rigid:zzsc1zNhBb5nwIRPeFpYOKgC3M8	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q5XIE8	uniprotkb:P85515	intact:EBI-15348306|ensembl:ENSRNOP00000023037	intact:EBI-8848568|ensembl:ENSRNOP00000026792	psi-mi:itm2b_rat(display_long)|uniprotkb:Itm2b(gene name)|psi-mi:Itm2b(display_short)|uniprotkb:Immature BRI2(gene name synonym)|uniprotkb:Transmembrane protein BRI(gene name synonym)	psi-mi:actz_rat(display_long)|uniprotkb:Actr1a(gene name)|psi-mi:Actr1a(display_short)|uniprotkb:Ctrn1(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Martins et al. (2018)	imex:IM-28469|pubmed:29476059	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26440627|imex:IM-28469-5	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSRNOG00000016271(gene)|ensembl:ENSRNOT00000023037(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001540"(amyloid-beta binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0010008"(endosome membrane)|go:"GO:0030660"(Golgi-associated vesicle membrane)|go:"GO:0031301"(integral component of organelle membrane)|go:"GO:0042985"(negative regulation of amyloid precursor protein biosynthetic process)|interpro:IPR007084(BRICHOS)|interpro:IPR040145|mint:Q5XIE8|refseq:NP_001006964.1|rgd:620727	refseq:NP_001099834.1|rgd:1307025|ensembl:ENSRNOG00000019725(gene)|ensembl:ENSRNOT00000026792(transcript)|go:"GO:0002177"(manchette)|go:"GO:0005524"(ATP binding)|go:"GO:0005813"(centrosome)|go:"GO:0005814"(centriole)|go:"GO:0007283"(spermatogenesis)|go:"GO:0030137"(COPI-coated vesicle)|go:"GO:0099738"(cell cortex region)|interpro:IPR004000(Actin/actin-like)|interpro:IPR004001(Actin, conserved site)|interpro:IPR020902|interpro:IPR043129|mint:P85515|reactome:R-RNO-2132295|reactome:R-RNO-2565942|reactome:R-RNO-3371497|reactome:R-RNO-380259|reactome:R-RNO-380270|reactome:R-RNO-380284|reactome:R-RNO-380320|reactome:R-RNO-5620912|reactome:R-RNO-6807878|reactome:R-RNO-6811436|reactome:R-RNO-8854518	-	-	-	figure legend:st1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10116(rat-hippocampus)|taxid:10116(Rattus norvegicus hippocampal neurons)	-	2020/10/30	2020/10/30	rogid:DtE+ZXAZKdCMvUW5K+jXQ5bH07M10116	rogid:aJHKOSj1qmZ7Pk8aZAyWWd8DEdw10116	rigid:zzsc1zNhBb5nwIRPeFpYOKgC3M8	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q5XIE8	uniprotkb:P07897	intact:EBI-15348306|ensembl:ENSRNOP00000023037	intact:EBI-1039762	psi-mi:itm2b_rat(display_long)|uniprotkb:Itm2b(gene name)|psi-mi:Itm2b(display_short)|uniprotkb:Immature BRI2(gene name synonym)|uniprotkb:Transmembrane protein BRI(gene name synonym)	psi-mi:pgca_rat(display_long)|uniprotkb:Acan(gene name)|psi-mi:Acan(display_short)|uniprotkb:Agc(gene name synonym)|uniprotkb:Agc1(gene name synonym)|uniprotkb:Cartilage-specific proteoglycan core protein(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Martins et al. (2018)	imex:IM-28469|pubmed:29476059	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26440627|imex:IM-28469-5	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSRNOG00000016271(gene)|ensembl:ENSRNOT00000023037(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001540"(amyloid-beta binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0010008"(endosome membrane)|go:"GO:0030660"(Golgi-associated vesicle membrane)|go:"GO:0031301"(integral component of organelle membrane)|go:"GO:0042985"(negative regulation of amyloid precursor protein biosynthetic process)|interpro:IPR007084(BRICHOS)|interpro:IPR040145|mint:Q5XIE8|refseq:NP_001006964.1|rgd:620727	rgd:68358|refseq:NP_071526.1|interpro:IPR001304(C-type lectin)|interpro:IPR016186(C-type lectin-like)|interpro:IPR018378|interpro:IPR016187(C-type lectin fold)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR003006(Immunoglobulin/major histocompatibility complex, conserved site)|interpro:IPR013106(Immunoglobulin V-set)|interpro:IPR000538(Link)|interpro:IPR000436(Sushi/SCR/CCP)|mint:P07897|go:"GO:0001501"(skeletal system development)|go:"GO:0001502"(cartilage condensation)|go:"GO:0001503"(ossification)|go:"GO:0002063"(chondrocyte development)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005540"(hyaluronic acid binding)|go:"GO:0005604"(basement membrane)|go:"GO:0005615"(extracellular space)|go:"GO:0007155"(cell adhesion)|go:"GO:0007417"(central nervous system development)|go:"GO:0007507"(heart development)|go:"GO:0009314"(response to radiation)|go:"GO:0009612"(response to mechanical stimulus)|go:"GO:0009629"(response to gravity)|go:"GO:0009749"(response to glucose)|go:"GO:0010447"(response to acidic pH)|go:"GO:0014070"(response to organic cyclic compound)|go:"GO:0021510"(spinal cord development)|go:"GO:0030166"(proteoglycan biosynthetic process)|go:"GO:0030199"(collagen fibril organization)|go:"GO:0030246"(carbohydrate binding)|go:"GO:0030336"(negative regulation of cell migration)|go:"GO:0031012"(extracellular matrix)|go:"GO:0042493"|go:"GO:0043005"(neuron projection)|go:"GO:0043025"(neuronal cell body)|go:"GO:0060591"(chondroblast differentiation)|go:"GO:0071363"(cellular response to growth factor stimulus)|go:"GO:0072534"(perineuronal net)|go:"GO:0098966"(perisynaptic extracellular matrix)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0098982"(GABA-ergic synapse)|rcsb pdb:1TDQ|reactome:R-RNO-1474228|reactome:R-RNO-2022854|reactome:R-RNO-2022857|reactome:R-RNO-3000178|go:"GO:0010259"(multicellular organism aging)|interpro:IPR003599(Immunoglobulin subtype)|interpro:IPR033987|interpro:IPR035976|interpro:IPR036179	-	-	-	figure legend:st1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10116(rat-hippocampus)|taxid:10116(Rattus norvegicus hippocampal neurons)	-	2020/10/30	2020/10/30	rogid:DtE+ZXAZKdCMvUW5K+jXQ5bH07M10116	rogid:p2ezYwvORuZanug55ifaXR11p/s10116	rigid:zzsc1zNhBb5nwIRPeFpYOKgC3M8	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q5XIE8	uniprotkb:P39069	intact:EBI-15348306|ensembl:ENSRNOP00000023037	intact:EBI-8848381|uniprotkb:Q5EBC5|uniprotkb:Q9JJN3	psi-mi:itm2b_rat(display_long)|uniprotkb:Itm2b(gene name)|psi-mi:Itm2b(display_short)|uniprotkb:Immature BRI2(gene name synonym)|uniprotkb:Transmembrane protein BRI(gene name synonym)	psi-mi:kad1_rat(display_long)|uniprotkb:Ak1(gene name)|psi-mi:Ak1(display_short)|uniprotkb:ATP-AMP transphosphorylase 1(gene name synonym)|uniprotkb:"ATP:AMP phosphotransferase"(gene name synonym)|uniprotkb:Adenylate monophosphate kinase(gene name synonym)|uniprotkb:Myokinase(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Martins et al. (2018)	imex:IM-28469|pubmed:29476059	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26440627|imex:IM-28469-5	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSRNOG00000016271(gene)|ensembl:ENSRNOT00000023037(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001540"(amyloid-beta binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0010008"(endosome membrane)|go:"GO:0030660"(Golgi-associated vesicle membrane)|go:"GO:0031301"(integral component of organelle membrane)|go:"GO:0042985"(negative regulation of amyloid precursor protein biosynthetic process)|interpro:IPR007084(BRICHOS)|interpro:IPR040145|mint:Q5XIE8|refseq:NP_001006964.1|rgd:620727	interpro:IPR028582|interpro:IPR033690|mint:P39069|interpro:IPR000850(Adenylate kinase)|interpro:IPR006267(Adenylate kinase, isozyme 1)|interpro:IPR027417|rgd:2076|refseq:NP_077325.2|go:"GO:0001520"(outer dense fiber)|go:"GO:0004017"(adenylate kinase activity)|go:"GO:0004550"(nucleoside diphosphate kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006165"(nucleoside diphosphate phosphorylation)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0006172"(ADP biosynthetic process)|go:"GO:0007517"(muscle organ development)|go:"GO:0009142"(nucleoside triphosphate biosynthetic process)|go:"GO:0010828"(positive regulation of glucose transmembrane transport)|go:"GO:0014042"(positive regulation of neuron maturation)|go:"GO:0014823"(response to activity)|go:"GO:0021549"(cerebellum development)|go:"GO:0021772"(olfactory bulb development)|go:"GO:0030017"(sarcomere)|go:"GO:0030182"(neuron differentiation)|go:"GO:0032355"(response to estradiol)|go:"GO:0033574"(response to testosterone)|go:"GO:0036126"(sperm flagellum)|go:"GO:0042493"|go:"GO:0043005"(neuron projection)|go:"GO:0046033"(AMP metabolic process)|go:"GO:0046034"(ATP metabolic process)|go:"GO:0046083"(adenine metabolic process)|go:"GO:0046103"(inosine biosynthetic process)	-	-	-	figure legend:st1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10116(rat-hippocampus)|taxid:10116(Rattus norvegicus hippocampal neurons)	-	2020/10/30	2020/10/30	rogid:DtE+ZXAZKdCMvUW5K+jXQ5bH07M10116	rogid:pihkCnUagKEubud3zNPgB95slaE10116	rigid:zzsc1zNhBb5nwIRPeFpYOKgC3M8	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q5XIE8	uniprotkb:Q9ER34	intact:EBI-15348306|ensembl:ENSRNOP00000023037	intact:EBI-919008|uniprotkb:Q6P6V3|ensembl:ENSRNOP00000029144	psi-mi:itm2b_rat(display_long)|uniprotkb:Itm2b(gene name)|psi-mi:Itm2b(display_short)|uniprotkb:Immature BRI2(gene name synonym)|uniprotkb:Transmembrane protein BRI(gene name synonym)	psi-mi:acon_rat(display_long)|uniprotkb:Aco2(gene name)|psi-mi:Aco2(display_short)|uniprotkb:Citrate hydro-lyase(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Martins et al. (2018)	imex:IM-28469|pubmed:29476059	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26440627|imex:IM-28469-5	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSRNOG00000016271(gene)|ensembl:ENSRNOT00000023037(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001540"(amyloid-beta binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0010008"(endosome membrane)|go:"GO:0030660"(Golgi-associated vesicle membrane)|go:"GO:0031301"(integral component of organelle membrane)|go:"GO:0042985"(negative regulation of amyloid precursor protein biosynthetic process)|interpro:IPR007084(BRICHOS)|interpro:IPR040145|mint:Q5XIE8|refseq:NP_001006964.1|rgd:620727	rgd:621360|refseq:NP_077374.2|ensembl:ENSRNOG00000024128(gene)|ensembl:ENSRNOT00000038612(transcript)|go:"GO:0001889"(liver development)|go:"GO:0003994"(aconitate hydratase activity)|go:"GO:0005506"(iron ion binding)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0006099"(tricarboxylic acid cycle)|go:"GO:0006101"(citrate metabolic process)|go:"GO:0006102"(isocitrate metabolic process)|go:"GO:0035900"(response to isolation stress)|go:"GO:0047780"(citrate dehydratase activity)|go:"GO:0051538"(3 iron, 4 sulfur cluster binding)|go:"GO:0051539"(4 iron, 4 sulfur cluster binding)|interpro:IPR000573(Aconitase A/isopropylmalate dehydratase small subunit, swivel)|interpro:IPR001030(Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha)|interpro:IPR006248(Aconitase, mitochondrial-like)|interpro:IPR015928(Aconitase/3-isopropylmalate dehydratase, swivel)|interpro:IPR015931(Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha, subdomains 1 and 3)|interpro:IPR015932(Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha, subdomain 2)|interpro:IPR018136|interpro:IPR036008|mint:Q9ER34|reactome:R-RNO-71403	-	-	-	figure legend:st1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10116(rat-hippocampus)|taxid:10116(Rattus norvegicus hippocampal neurons)	-	2020/10/30	2020/10/30	rogid:DtE+ZXAZKdCMvUW5K+jXQ5bH07M10116	rogid:Nk+zXn0ahm2Fy+jiP75Yp9gWYHk10116	rigid:zzsc1zNhBb5nwIRPeFpYOKgC3M8	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q5XIE8	uniprotkb:Q794F9	intact:EBI-15348306|ensembl:ENSRNOP00000023037	intact:EBI-919315	psi-mi:itm2b_rat(display_long)|uniprotkb:Itm2b(gene name)|psi-mi:Itm2b(display_short)|uniprotkb:Immature BRI2(gene name synonym)|uniprotkb:Transmembrane protein BRI(gene name synonym)	psi-mi:4f2_rat(display_long)|uniprotkb:Slc3a2(gene name)|psi-mi:Slc3a2(display_short)|uniprotkb:Solute carrier family 3 member 2(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Martins et al. (2018)	imex:IM-28469|pubmed:29476059	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26440627|imex:IM-28469-5	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSRNOG00000016271(gene)|ensembl:ENSRNOT00000023037(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001540"(amyloid-beta binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0010008"(endosome membrane)|go:"GO:0030660"(Golgi-associated vesicle membrane)|go:"GO:0031301"(integral component of organelle membrane)|go:"GO:0042985"(negative regulation of amyloid precursor protein biosynthetic process)|interpro:IPR007084(BRICHOS)|interpro:IPR040145|mint:Q5XIE8|refseq:NP_001006964.1|rgd:620727	rgd:3073|interpro:IPR006047(Glycosyl hydrolase, family 13, catalytic region)|interpro:IPR017853(Glycoside hydrolase, catalytic core)|refseq:NP_001258018.1|interpro:IPR031984|interpro:IPR042280|mint:Q794F9|interpro:IPR013780(Glycosyl hydrolase, family 13, all-beta)|go:"GO:0003725"(double-stranded RNA binding)|go:"GO:0003824"(catalytic activity)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005886"(plasma membrane)|go:"GO:0005975"(carbohydrate metabolic process)|go:"GO:0009925"(basal plasma membrane)|go:"GO:0009986"(cell surface)|go:"GO:0015173"(aromatic amino acid transmembrane transporter activity)|go:"GO:0015175"(neutral amino acid transmembrane transporter activity)|go:"GO:0015180"(L-alanine transmembrane transporter activity)|go:"GO:0015190"(L-leucine transmembrane transporter activity)|go:"GO:0015804"(neutral amino acid transport)|go:"GO:0015820"(leucine transport)|go:"GO:0015823"(phenylalanine transport)|go:"GO:0015827"(tryptophan transport)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0042470"(melanosome)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043330"(response to exogenous dsRNA)|go:"GO:0044225"(apical pole of neuron)|go:"GO:0045202"(synapse)|go:"GO:0046718"(viral entry into host cell)|go:"GO:0098713"(leucine import across plasma membrane)|go:"GO:1903801"(L-leucine import across plasma membrane)|go:"GO:1904273"(L-alanine import across plasma membrane)|go:"GO:1990184"(amino acid transport complex)|reactome:R-RNO-210991|reactome:R-RNO-352230|reactome:R-RNO-71240	-	-	-	figure legend:st1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10116(rat-hippocampus)|taxid:10116(Rattus norvegicus hippocampal neurons)	-	2020/10/30	2020/10/30	rogid:DtE+ZXAZKdCMvUW5K+jXQ5bH07M10116	rogid:gEQnTlE/6x+4eAArJn1IuzL9cJg10116	rigid:zzsc1zNhBb5nwIRPeFpYOKgC3M8	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q5XIE8	uniprotkb:O70351	intact:EBI-15348306|ensembl:ENSRNOP00000023037	intact:EBI-915644|uniprotkb:Q9QYD4	psi-mi:itm2b_rat(display_long)|uniprotkb:Itm2b(gene name)|psi-mi:Itm2b(display_short)|uniprotkb:Immature BRI2(gene name synonym)|uniprotkb:Transmembrane protein BRI(gene name synonym)	psi-mi:hcd2_rat(display_long)|uniprotkb:3-hydroxyacyl-CoA dehydrogenase type II(gene name synonym)|uniprotkb:Type II HADH(gene name synonym)|uniprotkb:3-hydroxy-2-methylbutyryl-CoA dehydrogenase(gene name synonym)|uniprotkb:Endoplasmic reticulum-associated amyloid beta-peptide-binding protein(gene name synonym)|uniprotkb:Hsd17b10(gene name)|psi-mi:Hsd17b10(display_short)|uniprotkb:Erab(gene name synonym)|uniprotkb:Hadh2(gene name synonym)|uniprotkb:Mitochondrial ribonuclease P protein 2(gene name synonym)|uniprotkb:17-beta-estradiol 17-dehydrogenase(gene name synonym)|uniprotkb:2-methyl-3-hydroxybutyryl-CoA dehydrogenase(gene name synonym)|uniprotkb:"3-alpha-(17-beta)-hydroxysteroid dehydrogenase (NAD(+))"(gene name synonym)|uniprotkb:"3alpha(or 20beta)-hydroxysteroid dehydrogenase"(gene name synonym)|uniprotkb:7-alpha-hydroxysteroid dehydrogenase(gene name synonym)|uniprotkb:Short chain dehydrogenase/reductase family 5C member 1(gene name synonym)|uniprotkb:Short-chain type dehydrogenase/reductase XH98G2(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Martins et al. (2018)	imex:IM-28469|pubmed:29476059	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26440627|imex:IM-28469-5	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSRNOG00000016271(gene)|ensembl:ENSRNOT00000023037(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001540"(amyloid-beta binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0010008"(endosome membrane)|go:"GO:0030660"(Golgi-associated vesicle membrane)|go:"GO:0031301"(integral component of organelle membrane)|go:"GO:0042985"(negative regulation of amyloid precursor protein biosynthetic process)|interpro:IPR007084(BRICHOS)|interpro:IPR040145|mint:Q5XIE8|refseq:NP_001006964.1|rgd:620727	go:"GO:0000049"(tRNA binding)|go:"GO:0001540"(amyloid-beta binding)|go:"GO:0003857"(3-hydroxyacyl-CoA dehydrogenase activity)|go:"GO:0004303"(estradiol 17-beta-dehydrogenase activity)|go:"GO:0005496"(steroid binding)|go:"GO:0005739"(mitochondrion)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0006550"(isoleucine catabolic process)|go:"GO:0006635"(fatty acid beta-oxidation)|go:"GO:0006699"(bile acid biosynthetic process)|go:"GO:0007005"(mitochondrion organization)|go:"GO:0007569"(cell aging)|go:"GO:0008207"(C21-steroid hormone metabolic process)|go:"GO:0008209"(androgen metabolic process)|go:"GO:0008210"(estrogen metabolic process)|go:"GO:0008709"(cholate 7-alpha-dehydrogenase activity)|mint:O70351|rgd:69231|refseq:NP_113870.1|interpro:IPR002347(Glucose/ribitol dehydrogenase)|interpro:IPR020904|interpro:IPR036291|go:"GO:0018454"(acetoacetyl-CoA reductase activity)|go:"GO:0030283"("testosterone dehydrogenase [NAD(P)] activity")|go:"GO:0030331"(estrogen receptor binding)|go:"GO:0030678"(mitochondrial ribonuclease P complex)|go:"GO:0033327"(Leydig cell differentiation)|go:"GO:0042645"(mitochondrial nucleoid)|go:"GO:0042802"(identical protein binding)|go:"GO:0044594"("17-beta-hydroxysteroid dehydrogenase (NAD+) activity")|go:"GO:0047015"(3-hydroxy-2-methylbutyryl-CoA dehydrogenase activity)|go:"GO:0047035"("testosterone dehydrogenase (NAD+) activity")|go:"GO:0047044"(androstan-3-alpha,17-beta-diol dehydrogenase activity)|go:"GO:0051287"(NAD binding)|go:"GO:0051289"(protein homotetramerization)|go:"GO:0062173"(brexanolone metabolic process)|go:"GO:0070901"(mitochondrial tRNA methylation)|go:"GO:0097745"(mitochondrial tRNA 5'-end processing)|go:"GO:0106281"("chenodeoxycholate 7-alpha-dehydrogenase (NAD+) activity")|go:"GO:0106282"("isoursodeoxycholate 7-beta-dehydrogenase (NAD+) activity")|go:"GO:0106283"("ursodeoxycholate 7-beta-dehydrogenase (NAD+) activity")|go:"GO:1990180"(mitochondrial tRNA 3'-end processing)|rcsb pdb:1E3S|rcsb pdb:1E3W|rcsb pdb:1E6W|reactome:R-RNO-70895	-	-	-	figure legend:st1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10116(rat-hippocampus)|taxid:10116(Rattus norvegicus hippocampal neurons)	-	2020/10/30	2020/10/30	rogid:DtE+ZXAZKdCMvUW5K+jXQ5bH07M10116	rogid:haa2iL54VH7fLot4uIyfXL+DMlA10116	rigid:zzsc1zNhBb5nwIRPeFpYOKgC3M8	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q5XIE8	uniprotkb:P62260	intact:EBI-15348306|ensembl:ENSRNOP00000023037	intact:EBI-356462|uniprotkb:P29360|uniprotkb:P42655|uniprotkb:Q63631|ensembl:ENSRNOP00000007100	psi-mi:itm2b_rat(display_long)|uniprotkb:Itm2b(gene name)|psi-mi:Itm2b(display_short)|uniprotkb:Immature BRI2(gene name synonym)|uniprotkb:Transmembrane protein BRI(gene name synonym)	psi-mi:1433e_rat(display_long)|uniprotkb:Ywhae(gene name)|psi-mi:Ywhae(display_short)|uniprotkb:Mitochondrial import stimulation factor L subunit(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Martins et al. (2018)	imex:IM-28469|pubmed:29476059	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26440627|imex:IM-28469-5	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSRNOG00000016271(gene)|ensembl:ENSRNOT00000023037(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001540"(amyloid-beta binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0010008"(endosome membrane)|go:"GO:0030660"(Golgi-associated vesicle membrane)|go:"GO:0031301"(integral component of organelle membrane)|go:"GO:0042985"(negative regulation of amyloid precursor protein biosynthetic process)|interpro:IPR007084(BRICHOS)|interpro:IPR040145|mint:Q5XIE8|refseq:NP_001006964.1|rgd:620727	rgd:62000|refseq:NP_113791.1|ensembl:ENSRNOG00000005290(gene)|ensembl:ENSRNOT00000007100(transcript)|go:"GO:0000165"(MAPK cascade)|go:"GO:0001764"(neuron migration)|go:"GO:0005246"(calcium channel regulator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005871"(kinesin complex)|go:"GO:0005886"(plasma membrane)|go:"GO:0006605"(protein targeting)|go:"GO:0007165"(signal transduction)|go:"GO:0008426"(protein kinase C inhibitor activity)|go:"GO:0015459"(potassium channel regulator activity)|go:"GO:0019899"(enzyme binding)|go:"GO:0019903"(protein phosphatase binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0021766"(hippocampus development)|go:"GO:0021987"(cerebral cortex development)|go:"GO:0030424"(axon)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0034504"(protein localization to nucleus)|go:"GO:0034605"(cellular response to heat)|go:"GO:0035308"(negative regulation of protein dephosphorylation)|go:"GO:0042470"(melanosome)|go:"GO:0042802"(identical protein binding)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045202"(synapse)|go:"GO:0046827"(positive regulation of protein export from nucleus)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0050815"(phosphoserine residue binding)|go:"GO:0051219"(phosphoprotein binding)|go:"GO:0051480"(regulation of cytosolic calcium ion concentration)|go:"GO:0060306"(regulation of membrane repolarization)|go:"GO:0090724"(central region of growth cone)|go:"GO:0097110"(scaffold protein binding)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099072"(regulation of postsynaptic membrane neurotransmitter receptor levels)|go:"GO:1901016"(regulation of potassium ion transmembrane transporter activity)|go:"GO:1901020"(negative regulation of calcium ion transmembrane transporter activity)|go:"GO:1902309"(negative regulation of peptidyl-serine dephosphorylation)|go:"GO:1905913"(negative regulation of calcium ion export across plasma membrane)|interpro:IPR000308(14-3-3 protein)|interpro:IPR023409|interpro:IPR023410|interpro:IPR036815|mint:P62260|reactome:R-RNO-111447|reactome:R-RNO-2028269|reactome:R-RNO-205025|reactome:R-RNO-2565942|reactome:R-RNO-3371453|reactome:R-RNO-3371511|reactome:R-RNO-380259|reactome:R-RNO-380270|reactome:R-RNO-380284|reactome:R-RNO-380320|reactome:R-RNO-5620912|reactome:R-RNO-5625740|reactome:R-RNO-5628897|reactome:R-RNO-75035|reactome:R-RNO-8854518|reactome:R-RNO-8876198|dip:DIP-37260N	-	-	-	figure legend:st1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10116(rat-hippocampus)|taxid:10116(Rattus norvegicus hippocampal neurons)	-	2020/10/30	2020/10/30	rogid:DtE+ZXAZKdCMvUW5K+jXQ5bH07M10116	rogid:mnuAjdnQZbMFojll2PnV3xFklXQ10116	rigid:zzsc1zNhBb5nwIRPeFpYOKgC3M8	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q5XIE8	uniprotkb:P08413	intact:EBI-15348306|ensembl:ENSRNOP00000023037	intact:EBI-916155	psi-mi:itm2b_rat(display_long)|uniprotkb:Itm2b(gene name)|psi-mi:Itm2b(display_short)|uniprotkb:Immature BRI2(gene name synonym)|uniprotkb:Transmembrane protein BRI(gene name synonym)	psi-mi:kcc2b_rat(display_long)|uniprotkb:Camk2b(gene name)|psi-mi:Camk2b(display_short)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Martins et al. (2018)	imex:IM-28469|pubmed:29476059	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26440627|imex:IM-28469-5	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSRNOG00000016271(gene)|ensembl:ENSRNOT00000023037(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001540"(amyloid-beta binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0010008"(endosome membrane)|go:"GO:0030660"(Golgi-associated vesicle membrane)|go:"GO:0031301"(integral component of organelle membrane)|go:"GO:0042985"(negative regulation of amyloid precursor protein biosynthetic process)|interpro:IPR007084(BRICHOS)|interpro:IPR040145|mint:Q5XIE8|refseq:NP_001006964.1|rgd:620727	rgd:2262|refseq:NP_001035815.1|refseq:NP_068507.2|go:"GO:0000082"(G1/S transition of mitotic cell cycle)|go:"GO:0002030"(inhibitory G protein-coupled receptor phosphorylation)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0004683"(calmodulin-dependent protein kinase activity)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005815"(microtubule organizing center)|go:"GO:0005829"(cytosol)|go:"GO:0005954"(calcium- and calmodulin-dependent protein kinase complex)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:0110088"(hippocampal neuron apoptotic process)|go:"GO:0006816"(calcium ion transport)|go:"GO:0010976"(positive regulation of neuron projection development)|go:"GO:0014069"(postsynaptic density)|go:"GO:0018105"(peptidyl-serine phosphorylation)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030425"(dendrite)|go:"GO:0032222"(regulation of synaptic transmission, cholinergic)|go:"GO:0032430"(positive regulation of phospholipase A2 activity)|go:"GO:0033017"(sarcoplasmic reticulum membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043005"(neuron projection)|go:"GO:0043204"(perikaryon)|go:"GO:0043274"(phospholipase binding)|go:"GO:0046686"(response to cadmium ion)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0048169"(regulation of long-term neuronal synaptic plasticity)|go:"GO:0048858"(cell projection morphogenesis)|go:"GO:0050885"(neuromuscular process controlling balance)|go:"GO:0051233"(spindle midzone)|go:"GO:0060291"(long-term synaptic potentiation)|go:"GO:0060466"(activation of meiosis involved in egg activation)|go:"GO:0061003"(positive regulation of dendritic spine morphogenesis)|go:"GO:0090129"(positive regulation of synapse maturation)|go:"GO:0098973"(structural constituent of postsynaptic actin cytoskeleton)|reactome:R-RNO-5578775|reactome:R-RNO-5673000|reactome:R-RNO-5673001|reactome:R-RNO-877300|reactome:R-RNO-936837|mint:P08413|go:"GO:1903076"(regulation of protein localization to plasma membrane)|go:"GO:1905375"(cellular response to homocysteine)|go:"GO:1990911"(response to psychosocial stress)|go:"GO:2001222"(regulation of neuron migration)|go:"GO:2001235"(positive regulation of apoptotic signaling pathway)|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR013543(Calcium/calmodulin dependent protein kinase II, association-domain)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR032710|rcsb pdb:6HCS|reactome:R-RNO-3371571|reactome:R-RNO-399719|reactome:R-RNO-438066|reactome:R-RNO-5576892|dip:DIP-36948N	-	-	-	figure legend:st1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10116(rat-hippocampus)|taxid:10116(Rattus norvegicus hippocampal neurons)	-	2020/10/30	2020/10/30	rogid:DtE+ZXAZKdCMvUW5K+jXQ5bH07M10116	rogid:RojSx9Ro3RlYG4LM8c8FroRaKzs10116	rigid:zzsc1zNhBb5nwIRPeFpYOKgC3M8	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q5XIE8	uniprotkb:P11275	intact:EBI-15348306|ensembl:ENSRNOP00000023037	intact:EBI-2640645	psi-mi:itm2b_rat(display_long)|uniprotkb:Itm2b(gene name)|psi-mi:Itm2b(display_short)|uniprotkb:Immature BRI2(gene name synonym)|uniprotkb:Transmembrane protein BRI(gene name synonym)	psi-mi:kcc2a_rat(display_long)|uniprotkb:Camk2a(gene name)|psi-mi:Camk2a(display_short)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Martins et al. (2018)	imex:IM-28469|pubmed:29476059	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26440627|imex:IM-28469-5	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSRNOG00000016271(gene)|ensembl:ENSRNOT00000023037(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001540"(amyloid-beta binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0010008"(endosome membrane)|go:"GO:0030660"(Golgi-associated vesicle membrane)|go:"GO:0031301"(integral component of organelle membrane)|go:"GO:0042985"(negative regulation of amyloid precursor protein biosynthetic process)|interpro:IPR007084(BRICHOS)|interpro:IPR040145|mint:Q5XIE8|refseq:NP_001006964.1|rgd:620727	rgd:2261|refseq:NP_037052.1|go:"GO:0000082"(G1/S transition of mitotic cell cycle)|go:"GO:0002931"(response to ischemia)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0004683"(calmodulin-dependent protein kinase activity)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005954"(calcium- and calmodulin-dependent protein kinase complex)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0006816"(calcium ion transport)|go:"GO:0009931"(calcium-dependent protein serine/threonine kinase activity)|go:"GO:0010666"(positive regulation of cardiac muscle cell apoptotic process)|go:"GO:0014069"(postsynaptic density)|go:"GO:0016020"(membrane)|go:"GO:0016301"(kinase activity)|go:"GO:0018105"(peptidyl-serine phosphorylation)|go:"GO:0030424"(axon)|go:"GO:0005829"(cytosol)|go:"GO:0030425"(dendrite)|go:"GO:0032794"(GTPase activating protein binding)|go:"GO:0032839"(dendrite cytoplasm)|go:"GO:0035235"(ionotropic glutamate receptor signaling pathway)|go:"GO:0035254"(glutamate receptor binding)|go:"GO:0038166"(angiotensin-activated signaling pathway)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043005"(neuron projection)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043197"(dendritic spine)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0046872"(metal ion binding)|go:"GO:0046928"(regulation of neurotransmitter secretion)|go:"GO:0048168"(regulation of neuronal synaptic plasticity)|go:"GO:0048813"(dendrite morphogenesis)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|go:"GO:0051346"(negative regulation of hydrolase activity)|go:"GO:0051928"(positive regulation of calcium ion transport)|go:"GO:0060996"(dendritic spine development)|go:"GO:0098685"(Schaffer collateral - CA1 synapse)|go:"GO:0098696"(regulation of neurotransmitter receptor localization to postsynaptic specialization membrane)|go:"GO:0098970"(postsynaptic neurotransmitter receptor diffusion trapping)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0098989"(NMDA selective glutamate receptor signaling pathway)|go:"GO:0099004"(calmodulin dependent kinase signaling pathway)|go:"GO:0099148"(regulation of synaptic vesicle docking)|go:"GO:0099523"(presynaptic cytosol)|go:"GO:0099524"(postsynaptic cytosol)|go:"GO:0099573"(glutamatergic postsynaptic density)|go:"GO:0099634"(postsynaptic specialization membrane)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:1902108"(regulation of mitochondrial membrane permeability involved in apoptotic process)|go:"GO:1903076"(regulation of protein localization to plasma membrane)|go:"GO:1990443"(peptidyl-threonine autophosphorylation)|go:"GO:2000124"(regulation of endocannabinoid signaling pathway)|go:"GO:2001222"(regulation of neuron migration)|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR013543(Calcium/calmodulin dependent protein kinase II, association-domain)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR032710|rcsb pdb:1CDM|rcsb pdb:1CM1|rcsb pdb:1CM4|rcsb pdb:5U6Y|reactome:R-RNO-3371571|reactome:R-RNO-399719|reactome:R-RNO-4086398|reactome:R-RNO-438066|reactome:R-RNO-5576892|reactome:R-RNO-5578775|reactome:R-RNO-5673000|reactome:R-RNO-5673001|reactome:R-RNO-877300|reactome:R-RNO-936837|dip:DIP-29639N|mint:P11275	-	-	-	figure legend:st1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10116(rat-hippocampus)|taxid:10116(Rattus norvegicus hippocampal neurons)	-	2020/10/30	2020/10/30	rogid:DtE+ZXAZKdCMvUW5K+jXQ5bH07M10116	rogid:mHdSlhGhe3sMOyO+YGwROtGOGfY10116	rigid:zzsc1zNhBb5nwIRPeFpYOKgC3M8	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q5XIE8	uniprotkb:Q5FVI4	intact:EBI-15348306|ensembl:ENSRNOP00000023037	intact:EBI-26439720|ensembl:ENSRNOP00000024867|ensembl:ENSRNOP00000066509	psi-mi:itm2b_rat(display_long)|uniprotkb:Itm2b(gene name)|psi-mi:Itm2b(display_short)|uniprotkb:Immature BRI2(gene name synonym)|uniprotkb:Transmembrane protein BRI(gene name synonym)	psi-mi:cend_rat(display_long)|uniprotkb:Cend1(gene name)|psi-mi:Cend1(display_short)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Martins et al. (2018)	imex:IM-28469|pubmed:29476059	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26440627|imex:IM-28469-5	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSRNOG00000016271(gene)|ensembl:ENSRNOT00000023037(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001540"(amyloid-beta binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0010008"(endosome membrane)|go:"GO:0030660"(Golgi-associated vesicle membrane)|go:"GO:0031301"(integral component of organelle membrane)|go:"GO:0042985"(negative regulation of amyloid precursor protein biosynthetic process)|interpro:IPR007084(BRICHOS)|interpro:IPR040145|mint:Q5XIE8|refseq:NP_001006964.1|rgd:620727	ensembl:ENSRNOG00000018448(gene)|ensembl:ENSRNOG00000045680(gene)|ensembl:ENSRNOT00000024867(transcript)|ensembl:ENSRNOT00000074016(transcript)|go:"GO:0007628"(adult walking behavior)|go:"GO:0016021"(integral component of membrane)|go:"GO:0021686"(cerebellar granular layer maturation)|go:"GO:0021702"(cerebellar Purkinje cell differentiation)|go:"GO:0021933"(radial glia guided migration of cerebellar granule cell)|go:"GO:0021941"(negative regulation of cerebellar granule cell precursor proliferation)|go:"GO:0030182"(neuron differentiation)|interpro:IPR020162|mint:Q5FVI4|refseq:NP_001014185.1|refseq:XP_003749055.1|refseq:XP_008772956.1|rgd:1309401	-	-	-	figure legend:st1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10116(rat-hippocampus)|taxid:10116(Rattus norvegicus hippocampal neurons)	-	2020/10/30	2020/10/30	rogid:DtE+ZXAZKdCMvUW5K+jXQ5bH07M10116	rogid:J40Tb1hzqxbyIVe+3MXRCNvbNOo10116	rigid:zzsc1zNhBb5nwIRPeFpYOKgC3M8	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q5XIE8	uniprotkb:P23358	intact:EBI-15348306|ensembl:ENSRNOP00000023037	intact:EBI-916883|ensembl:ENSRNOP00000041462	psi-mi:itm2b_rat(display_long)|uniprotkb:Itm2b(gene name)|psi-mi:Itm2b(display_short)|uniprotkb:Immature BRI2(gene name synonym)|uniprotkb:Transmembrane protein BRI(gene name synonym)	psi-mi:rl12_rat(display_long)|uniprotkb:Rpl12(gene name)|psi-mi:Rpl12(display_short)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Martins et al. (2018)	imex:IM-28469|pubmed:29476059	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26440627|imex:IM-28469-5	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSRNOG00000016271(gene)|ensembl:ENSRNOT00000023037(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001540"(amyloid-beta binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0010008"(endosome membrane)|go:"GO:0030660"(Golgi-associated vesicle membrane)|go:"GO:0031301"(integral component of organelle membrane)|go:"GO:0042985"(negative regulation of amyloid precursor protein biosynthetic process)|interpro:IPR007084(BRICHOS)|interpro:IPR040145|mint:Q5XIE8|refseq:NP_001006964.1|rgd:620727	rgd:1565106|refseq:NP_001102668.1|refseq:XP_006227318.1|refseq:XP_006256697.1|ensembl:ENSRNOG00000028993(gene)|ensembl:ENSRNOT00000042736(transcript)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005634"(nucleus)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006412"(translation)|go:"GO:0014069"(postsynaptic density)|go:"GO:0015934"(large ribosomal subunit)|go:"GO:0022625"(cytosolic large ribosomal subunit)|go:"GO:0022626"(cytosolic ribosome)|go:"GO:0045901"(positive regulation of translational elongation)|go:"GO:0070180"(large ribosomal subunit rRNA binding)|interpro:IPR000911(Ribosomal protein L11)|interpro:IPR020783|interpro:IPR020784|interpro:IPR020785|interpro:IPR036769|interpro:IPR036796|mint:P23358|reactome:R-RNO-156827|reactome:R-RNO-1799339|reactome:R-RNO-6791226|reactome:R-RNO-72689|reactome:R-RNO-72706|reactome:R-RNO-975956|reactome:R-RNO-975957	-	-	-	figure legend:st1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10116(rat-hippocampus)|taxid:10116(Rattus norvegicus hippocampal neurons)	-	2020/10/30	2020/10/30	rogid:DtE+ZXAZKdCMvUW5K+jXQ5bH07M10116	rogid:HD3+OCF6/IffH5e5AZRD235vais10116	rigid:zzsc1zNhBb5nwIRPeFpYOKgC3M8	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q5XIE8	uniprotkb:Q9QUL6	intact:EBI-15348306|ensembl:ENSRNOP00000023037	intact:EBI-925794	psi-mi:itm2b_rat(display_long)|uniprotkb:Itm2b(gene name)|psi-mi:Itm2b(display_short)|uniprotkb:Immature BRI2(gene name synonym)|uniprotkb:Transmembrane protein BRI(gene name synonym)	psi-mi:nsf_rat(display_long)|uniprotkb:Nsf(gene name)|psi-mi:Nsf(display_short)|uniprotkb:Erg1(gene name synonym)|uniprotkb:N-ethylmaleimide-sensitive fusion protein(gene name synonym)|uniprotkb:Vesicular-fusion protein NSF(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Martins et al. (2018)	imex:IM-28469|pubmed:29476059	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26440627|imex:IM-28469-5	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSRNOG00000016271(gene)|ensembl:ENSRNOT00000023037(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001540"(amyloid-beta binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0010008"(endosome membrane)|go:"GO:0030660"(Golgi-associated vesicle membrane)|go:"GO:0031301"(integral component of organelle membrane)|go:"GO:0042985"(negative regulation of amyloid precursor protein biosynthetic process)|interpro:IPR007084(BRICHOS)|interpro:IPR040145|mint:Q5XIE8|refseq:NP_001006964.1|rgd:620727	rgd:621594|refseq:NP_068516.1|interpro:IPR009010(Aspartate decarboxylase-like fold)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR003959(AAA ATPase, core)|interpro:IPR003960(AAA ATPase, conserved site)|interpro:IPR003338(AAA ATPase VAT, N-terminal)|interpro:IPR004201(Cell division protein 48, CDC48, domain 2)|interpro:IPR027417|interpro:IPR029067|mint:Q9QUL6|interpro:IPR039812|interpro:IPR041569|go:"GO:0000149"(SNARE binding)|go:"GO:0001921"(positive regulation of receptor recycling)|go:"GO:0002090"(regulation of receptor internalization)|go:"GO:0005524"(ATP binding)|go:"GO:0005795"(Golgi stack)|go:"GO:0005886"(plasma membrane)|go:"GO:0006813"(potassium ion transport)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006891"(intra-Golgi vesicle-mediated transport)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0014069"(postsynaptic density)|go:"GO:0015031"(protein transport)|go:"GO:0016192"(vesicle-mediated transport)|go:"GO:0017075"(syntaxin-1 binding)|go:"GO:0017157"(regulation of exocytosis)|go:"GO:0019901"(protein kinase binding)|go:"GO:0019905"(syntaxin binding)|go:"GO:0030165"(PDZ domain binding)|go:"GO:0031267"(small GTPase binding)|go:"GO:0031748"(D1 dopamine receptor binding)|go:"GO:0032984"(protein-containing complex disassembly)|go:"GO:0035255"(ionotropic glutamate receptor binding)|go:"GO:0035494"(SNARE complex disassembly)|go:"GO:0043001"(Golgi to plasma membrane protein transport)|go:"GO:0043008"(ATP-dependent protein binding)|go:"GO:0043198"(dendritic shaft)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045732"(positive regulation of protein catabolic process)|go:"GO:0046872"(metal ion binding)|go:"GO:0048211"(Golgi vesicle docking)|go:"GO:0140545"(protein disaggregase activity)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|reactome:R-RNO-204005|reactome:R-RNO-416993|reactome:R-RNO-6807878|reactome:R-RNO-6811434|reactome:R-RNO-6811438|reactome:R-RNO-6811440	-	-	-	figure legend:st1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10116(rat-hippocampus)|taxid:10116(Rattus norvegicus hippocampal neurons)	-	2020/10/30	2020/10/30	rogid:DtE+ZXAZKdCMvUW5K+jXQ5bH07M10116	rogid:auiPGWRTO2wORmMBlQZuzHooO+M10116	rigid:zzsc1zNhBb5nwIRPeFpYOKgC3M8	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q5XIE8	uniprotkb:P69897	intact:EBI-15348306|ensembl:ENSRNOP00000023037	intact:EBI-350912|uniprotkb:P05218|uniprotkb:Q6P9X8|uniprotkb:Q9CY33|uniprotkb:Q8WUC1|ensembl:ENSRNOP00000075269	psi-mi:itm2b_rat(display_long)|uniprotkb:Itm2b(gene name)|psi-mi:Itm2b(display_short)|uniprotkb:Immature BRI2(gene name synonym)|uniprotkb:Transmembrane protein BRI(gene name synonym)	psi-mi:tbb5_rat(display_long)|uniprotkb:Tubb5(gene name)|psi-mi:Tubb5(display_short)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Martins et al. (2018)	imex:IM-28469|pubmed:29476059	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26440627|imex:IM-28469-5	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSRNOG00000016271(gene)|ensembl:ENSRNOT00000023037(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001540"(amyloid-beta binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0010008"(endosome membrane)|go:"GO:0030660"(Golgi-associated vesicle membrane)|go:"GO:0031301"(integral component of organelle membrane)|go:"GO:0042985"(negative regulation of amyloid precursor protein biosynthetic process)|interpro:IPR007084(BRICHOS)|interpro:IPR040145|mint:Q5XIE8|refseq:NP_001006964.1|rgd:620727	rgd:628596|refseq:NP_775125.1|go:"GO:0005634"(nucleus)|go:"GO:0005641"(nuclear envelope lumen)|go:"GO:0005737"(cytoplasm)|go:"GO:0005874"(microtubule)|go:"GO:0007017"(microtubule-based process)|go:"GO:0009987"(cellular process)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032794"(GTPase activating protein binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0036464"(cytoplasmic ribonucleoprotein granule)|go:"GO:0042288"(MHC class I protein binding)|go:"GO:0044297"(cell body)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045121"(membrane raft)|go:"GO:0050807"(regulation of synapse organization)|go:"GO:0051225"(spindle assembly)|interpro:IPR000217(Tubulin)|interpro:IPR002453(Beta tubulin)|go:"GO:0005525"(GTP binding)|interpro:IPR003008(Tubulin/FtsZ, GTPase)|interpro:IPR008280(Tubulin/FtsZ, C-terminal)|interpro:IPR013838(Beta tubulin, autoregulation binding site)|interpro:IPR017975|interpro:IPR018316|interpro:IPR023123|interpro:IPR036525|interpro:IPR037103|mint:P69897|reactome:R-RNO-2565942|reactome:R-RNO-380259|reactome:R-RNO-380270|reactome:R-RNO-380284|reactome:R-RNO-380320|reactome:R-RNO-5620912|reactome:R-RNO-6798695|reactome:R-RNO-8854518|ensembl:ENSRNOG00000061216(gene)|ensembl:ENSRNOT00000079854(transcript)|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0005200"(structural constituent of cytoskeleton)	-	-	-	figure legend:st1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10116(rat-hippocampus)|taxid:10116(Rattus norvegicus hippocampal neurons)	-	2020/10/30	2020/10/30	rogid:DtE+ZXAZKdCMvUW5K+jXQ5bH07M10116	rogid:B6pmb1dvCroZXGd/1Zazi+s72GA10116	rigid:zzsc1zNhBb5nwIRPeFpYOKgC3M8	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q5XIE8	uniprotkb:Q6P9T8	intact:EBI-15348306|ensembl:ENSRNOP00000023037	intact:EBI-919099	psi-mi:itm2b_rat(display_long)|uniprotkb:Itm2b(gene name)|psi-mi:Itm2b(display_short)|uniprotkb:Immature BRI2(gene name synonym)|uniprotkb:Transmembrane protein BRI(gene name synonym)	psi-mi:tbb4b_rat(display_long)|uniprotkb:Tubb4b(gene name)|psi-mi:Tubb4b(display_short)|uniprotkb:Tubb2c(gene name synonym)|uniprotkb:Tubulin beta-2C chain(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Martins et al. (2018)	imex:IM-28469|pubmed:29476059	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26440627|imex:IM-28469-5	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSRNOG00000016271(gene)|ensembl:ENSRNOT00000023037(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001540"(amyloid-beta binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0010008"(endosome membrane)|go:"GO:0030660"(Golgi-associated vesicle membrane)|go:"GO:0031301"(integral component of organelle membrane)|go:"GO:0042985"(negative regulation of amyloid precursor protein biosynthetic process)|interpro:IPR007084(BRICHOS)|interpro:IPR040145|mint:Q5XIE8|refseq:NP_001006964.1|rgd:620727	interpro:IPR008280(Tubulin/FtsZ, C-terminal)|interpro:IPR000217(Tubulin)|interpro:IPR018316|interpro:IPR017975|interpro:IPR003008(Tubulin/FtsZ, GTPase)|rgd:735101|refseq:NP_954525.1|interpro:IPR013838(Beta tubulin, autoregulation binding site)|interpro:IPR002453(Beta tubulin)|interpro:IPR023123|mint:Q6P9T8|interpro:IPR036525|interpro:IPR037103|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0003725"(double-stranded RNA binding)|go:"GO:0005200"(structural constituent of cytoskeleton)|go:"GO:0005525"(GTP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005874"(microtubule)|reactome:R-RNO-190840|reactome:R-RNO-2132295|reactome:R-RNO-2467813|reactome:R-RNO-2500257|reactome:R-RNO-2565942|reactome:R-RNO-3371497|reactome:R-RNO-380259|reactome:R-RNO-380270|reactome:R-RNO-380284|reactome:R-RNO-380320|reactome:R-RNO-437239|reactome:R-RNO-5610787|reactome:R-RNO-5617833|reactome:R-RNO-5620912|reactome:R-RNO-5620924|reactome:R-RNO-5626467|reactome:R-RNO-5663220|reactome:R-RNO-6798695|reactome:R-RNO-6807878|reactome:R-RNO-6811434|reactome:R-RNO-6811436|reactome:R-RNO-68877|reactome:R-RNO-8852276|reactome:R-RNO-8854518|reactome:R-RNO-8955332|reactome:R-RNO-9646399|reactome:R-RNO-9648025|reactome:R-RNO-9668328|reactome:R-RNO-983189	-	-	-	figure legend:st1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10116(rat-hippocampus)|taxid:10116(Rattus norvegicus hippocampal neurons)	-	2020/10/30	2020/10/30	rogid:DtE+ZXAZKdCMvUW5K+jXQ5bH07M10116	rogid:1RJgLTml+eflSvmnOyLoI1pFFTc10116	rigid:zzsc1zNhBb5nwIRPeFpYOKgC3M8	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q5XIE8	uniprotkb:Q4QRB4	intact:EBI-15348306|ensembl:ENSRNOP00000023037	intact:EBI-919537|uniprotkb:Q8K5B6|ensembl:ENSRNOP00000023452	psi-mi:itm2b_rat(display_long)|uniprotkb:Itm2b(gene name)|psi-mi:Itm2b(display_short)|uniprotkb:Immature BRI2(gene name synonym)|uniprotkb:Transmembrane protein BRI(gene name synonym)	psi-mi:tbb3_rat(display_long)|uniprotkb:Tubb3(gene name)|psi-mi:Tubb3(display_short)|uniprotkb:Neuron-specific class III beta-tubulin(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Martins et al. (2018)	imex:IM-28469|pubmed:29476059	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26440627|imex:IM-28469-5	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSRNOG00000016271(gene)|ensembl:ENSRNOT00000023037(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001540"(amyloid-beta binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0010008"(endosome membrane)|go:"GO:0030660"(Golgi-associated vesicle membrane)|go:"GO:0031301"(integral component of organelle membrane)|go:"GO:0042985"(negative regulation of amyloid precursor protein biosynthetic process)|interpro:IPR007084(BRICHOS)|interpro:IPR040145|mint:Q5XIE8|refseq:NP_001006964.1|rgd:620727	rgd:628595|refseq:NP_640347.2|ensembl:ENSRNOG00000017209(gene)|ensembl:ENSRNOT00000023452(transcript)|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0005200"(structural constituent of cytoskeleton)|go:"GO:0005525"(GTP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005874"(microtubule)|go:"GO:0007411"(axon guidance)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0030027"(lamellipodium)|go:"GO:0030175"(filopodium)|go:"GO:0030182"(neuron differentiation)|go:"GO:0030424"(axon)|go:"GO:0030425"(dendrite)|go:"GO:0030426"(growth cone)|go:"GO:0038007"(netrin-activated signaling pathway)|go:"GO:0042277"(peptide binding)|go:"GO:0043025"(neuronal cell body)|go:"GO:0071944"(cell periphery)|go:"GO:1990791"(dorsal root ganglion development)|go:"GO:1990890"(netrin receptor binding)|interpro:IPR000217(Tubulin)|interpro:IPR002453(Beta tubulin)|interpro:IPR003008(Tubulin/FtsZ, GTPase)|interpro:IPR008280(Tubulin/FtsZ, C-terminal)|interpro:IPR013838(Beta tubulin, autoregulation binding site)|interpro:IPR017975|interpro:IPR018316|interpro:IPR023123|interpro:IPR036525|interpro:IPR037103|mint:Q4QRB4|reactome:R-RNO-190840|reactome:R-RNO-2132295|reactome:R-RNO-2467813|reactome:R-RNO-2500257|reactome:R-RNO-3371497|reactome:R-RNO-380320|reactome:R-RNO-437239|reactome:R-RNO-5610787|reactome:R-RNO-5617833|reactome:R-RNO-5620924|reactome:R-RNO-5626467|reactome:R-RNO-5663220|reactome:R-RNO-6807878|reactome:R-RNO-6811434|reactome:R-RNO-6811436|reactome:R-RNO-68877|reactome:R-RNO-8852276|reactome:R-RNO-8955332|reactome:R-RNO-9646399|reactome:R-RNO-9648025|reactome:R-RNO-9668328|reactome:R-RNO-983189	-	-	-	figure legend:st1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10116(rat-hippocampus)|taxid:10116(Rattus norvegicus hippocampal neurons)	-	2020/10/30	2020/10/30	rogid:DtE+ZXAZKdCMvUW5K+jXQ5bH07M10116	rogid:KhUQ3YFdcJvjwoHGykl7dv90vX810116	rigid:zzsc1zNhBb5nwIRPeFpYOKgC3M8	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q5XIE8	uniprotkb:P85108	intact:EBI-15348306|ensembl:ENSRNOP00000023037	intact:EBI-2696554|ensembl:ENSRNOP00000023611|ensembl:ENSRNOP00000071729	psi-mi:itm2b_rat(display_long)|uniprotkb:Itm2b(gene name)|psi-mi:Itm2b(display_short)|uniprotkb:Immature BRI2(gene name synonym)|uniprotkb:Transmembrane protein BRI(gene name synonym)	psi-mi:tbb2a_rat(display_long)|uniprotkb:Tubb2a(gene name)|psi-mi:Tubb2a(display_short)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Martins et al. (2018)	imex:IM-28469|pubmed:29476059	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26440627|imex:IM-28469-5	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSRNOG00000016271(gene)|ensembl:ENSRNOT00000023037(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001540"(amyloid-beta binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0010008"(endosome membrane)|go:"GO:0030660"(Golgi-associated vesicle membrane)|go:"GO:0031301"(integral component of organelle membrane)|go:"GO:0042985"(negative regulation of amyloid precursor protein biosynthetic process)|interpro:IPR007084(BRICHOS)|interpro:IPR040145|mint:Q5XIE8|refseq:NP_001006964.1|rgd:620727	rgd:1588452|refseq:NP_001102589.1|ensembl:ENSRNOG00000017558(gene)|ensembl:ENSRNOT00000023611(transcript)|ensembl:ENSRNOT00000086264(transcript)|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0001764"(neuron migration)|go:"GO:0005200"(structural constituent of cytoskeleton)|go:"GO:0005525"(GTP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005874"(microtubule)|interpro:IPR000217(Tubulin)|interpro:IPR002453(Beta tubulin)|interpro:IPR003008(Tubulin/FtsZ, GTPase)|interpro:IPR008280(Tubulin/FtsZ, C-terminal)|interpro:IPR013838(Beta tubulin, autoregulation binding site)|interpro:IPR017975|interpro:IPR018316|interpro:IPR023123|interpro:IPR036525|interpro:IPR037103|mint:P85108|reactome:R-RNO-190840|reactome:R-RNO-2132295|reactome:R-RNO-2467813|reactome:R-RNO-2500257|reactome:R-RNO-3371497|reactome:R-RNO-380320|reactome:R-RNO-437239|reactome:R-RNO-5610787|reactome:R-RNO-5617833|reactome:R-RNO-5620924|reactome:R-RNO-5626467|reactome:R-RNO-5663220|reactome:R-RNO-6807878|reactome:R-RNO-6811434|reactome:R-RNO-6811436|reactome:R-RNO-68877|reactome:R-RNO-8852276|reactome:R-RNO-8955332|reactome:R-RNO-9646399|reactome:R-RNO-9648025|reactome:R-RNO-9668328|reactome:R-RNO-983189	-	-	-	figure legend:st1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10116(rat-hippocampus)|taxid:10116(Rattus norvegicus hippocampal neurons)	-	2020/10/30	2020/10/30	rogid:DtE+ZXAZKdCMvUW5K+jXQ5bH07M10116	rogid:XN9uTGU0KxQjMod0AGnM+XJoHyk10116	rigid:zzsc1zNhBb5nwIRPeFpYOKgC3M8	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q5XIE8	uniprotkb:Q5XIF6	intact:EBI-15348306|ensembl:ENSRNOP00000023037	intact:EBI-2255850|ensembl:ENSRNOP00000004797	psi-mi:itm2b_rat(display_long)|uniprotkb:Itm2b(gene name)|psi-mi:Itm2b(display_short)|uniprotkb:Immature BRI2(gene name synonym)|uniprotkb:Transmembrane protein BRI(gene name synonym)	psi-mi:tba4a_rat(display_long)|uniprotkb:Tuba4a(gene name)|psi-mi:Tuba4a(display_short)|uniprotkb:Tuba4(gene name synonym)|uniprotkb:Tubulin alpha-4 chain(gene name synonym)|uniprotkb:Alpha-tubulin 4(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Martins et al. (2018)	imex:IM-28469|pubmed:29476059	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26440627|imex:IM-28469-5	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSRNOG00000016271(gene)|ensembl:ENSRNOT00000023037(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001540"(amyloid-beta binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0010008"(endosome membrane)|go:"GO:0030660"(Golgi-associated vesicle membrane)|go:"GO:0031301"(integral component of organelle membrane)|go:"GO:0042985"(negative regulation of amyloid precursor protein biosynthetic process)|interpro:IPR007084(BRICHOS)|interpro:IPR040145|mint:Q5XIE8|refseq:NP_001006964.1|rgd:620727	rgd:1359623|refseq:NP_001007005.1|ensembl:ENSRNOG00000003597(gene)|ensembl:ENSRNOT00000004797(transcript)|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0005200"(structural constituent of cytoskeleton)|go:"GO:0005525"(GTP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005874"(microtubule)|go:"GO:0019899"(enzyme binding)|go:"GO:0019901"(protein kinase binding)|interpro:IPR000217(Tubulin)|interpro:IPR002452(Alpha tubulin)|interpro:IPR003008(Tubulin/FtsZ, GTPase)|interpro:IPR008280(Tubulin/FtsZ, C-terminal)|interpro:IPR017975|interpro:IPR018316|interpro:IPR023123|interpro:IPR036525|interpro:IPR037103|mint:Q5XIF6|reactome:R-RNO-114608|reactome:R-RNO-190840|reactome:R-RNO-2132295|reactome:R-RNO-2467813|reactome:R-RNO-2500257|reactome:R-RNO-2565942|reactome:R-RNO-3371497|reactome:R-RNO-380259|reactome:R-RNO-380270|reactome:R-RNO-380284|reactome:R-RNO-380320|reactome:R-RNO-437239|reactome:R-RNO-5610787|reactome:R-RNO-5617833|reactome:R-RNO-5620912|reactome:R-RNO-5620924|reactome:R-RNO-5626467|reactome:R-RNO-5663220|reactome:R-RNO-6807878|reactome:R-RNO-6811434|reactome:R-RNO-6811436|reactome:R-RNO-68877|reactome:R-RNO-8852276|reactome:R-RNO-8854518|reactome:R-RNO-8955332|reactome:R-RNO-9646399|reactome:R-RNO-9648025|reactome:R-RNO-9668328|reactome:R-RNO-983189	-	-	-	figure legend:st1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10116(rat-hippocampus)|taxid:10116(Rattus norvegicus hippocampal neurons)	-	2020/10/30	2020/10/30	rogid:DtE+ZXAZKdCMvUW5K+jXQ5bH07M10116	rogid:6Oj9O8u7E6cLUJ1eT6y5slbk7uQ10116	rigid:zzsc1zNhBb5nwIRPeFpYOKgC3M8	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q5XIE8	uniprotkb:P68370	intact:EBI-15348306|ensembl:ENSRNOP00000023037	intact:EBI-349571|uniprotkb:P02551|uniprotkb:P05210|uniprotkb:P05212|uniprotkb:Q6P6G6|ensembl:ENSRNOP00000075232	psi-mi:itm2b_rat(display_long)|uniprotkb:Itm2b(gene name)|psi-mi:Itm2b(display_short)|uniprotkb:Immature BRI2(gene name synonym)|uniprotkb:Transmembrane protein BRI(gene name synonym)	psi-mi:tba1a_rat(display_long)|uniprotkb:Tuba1a(gene name)|psi-mi:Tuba1a(display_short)|uniprotkb:Tuba1(gene name synonym)|uniprotkb:Tubulin alpha-1 chain(gene name synonym)|uniprotkb:Alpha-tubulin 1(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Martins et al. (2018)	imex:IM-28469|pubmed:29476059	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26440627|imex:IM-28469-5	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSRNOG00000016271(gene)|ensembl:ENSRNOT00000023037(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001540"(amyloid-beta binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0010008"(endosome membrane)|go:"GO:0030660"(Golgi-associated vesicle membrane)|go:"GO:0031301"(integral component of organelle membrane)|go:"GO:0042985"(negative regulation of amyloid precursor protein biosynthetic process)|interpro:IPR007084(BRICHOS)|interpro:IPR040145|mint:Q5XIE8|refseq:NP_001006964.1|rgd:620727	rgd:619717|refseq:NP_071634.1|go:"GO:0005200"(structural constituent of cytoskeleton)|go:"GO:0005525"(GTP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005874"(microtubule)|go:"GO:0005881"(cytoplasmic microtubule)|go:"GO:0007017"(microtubule-based process)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0031594"(neuromuscular junction)|go:"GO:0036464"(cytoplasmic ribonucleoprotein granule)|go:"GO:0042802"(identical protein binding)|go:"GO:0043209"(myelin sheath)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045121"(membrane raft)|go:"GO:0050807"(regulation of synapse organization)|go:"GO:0055037"(recycling endosome)|interpro:IPR000217(Tubulin)|interpro:IPR002452(Alpha tubulin)|interpro:IPR003008(Tubulin/FtsZ, GTPase)|interpro:IPR008280(Tubulin/FtsZ, C-terminal)|interpro:IPR017975|interpro:IPR018316|ensembl:ENSRNOG00000060728(gene)|ensembl:ENSRNOT00000083156(transcript)|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0000278"(mitotic cell cycle)|interpro:IPR023123|interpro:IPR036525|interpro:IPR037103|mint:P68370|reactome:R-RNO-190840|reactome:R-RNO-2132295|reactome:R-RNO-2467813|reactome:R-RNO-2500257|reactome:R-RNO-2565942|reactome:R-RNO-3371497|reactome:R-RNO-380259|reactome:R-RNO-380270|reactome:R-RNO-380284|reactome:R-RNO-380320|reactome:R-RNO-437239|reactome:R-RNO-5610787|reactome:R-RNO-5617833|reactome:R-RNO-5620912|reactome:R-RNO-5620924|reactome:R-RNO-5626467|reactome:R-RNO-5663220|reactome:R-RNO-6807878|reactome:R-RNO-6811434|reactome:R-RNO-6811436|reactome:R-RNO-68877|reactome:R-RNO-8852276|reactome:R-RNO-8854518|reactome:R-RNO-8955332|reactome:R-RNO-9646399|reactome:R-RNO-9648025|reactome:R-RNO-9668328|reactome:R-RNO-983189	-	-	-	figure legend:st1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10116(rat-hippocampus)|taxid:10116(Rattus norvegicus hippocampal neurons)	-	2020/10/30	2020/10/30	rogid:DtE+ZXAZKdCMvUW5K+jXQ5bH07M10116	rogid:1CzEzrf5y8hrQRPKgWQS1Wm1aCY10116	rigid:zzsc1zNhBb5nwIRPeFpYOKgC3M8	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q5XIE8	uniprotkb:Q68A21	intact:EBI-15348306|ensembl:ENSRNOP00000023037	intact:EBI-26437870	psi-mi:itm2b_rat(display_long)|uniprotkb:Itm2b(gene name)|psi-mi:Itm2b(display_short)|uniprotkb:Immature BRI2(gene name synonym)|uniprotkb:Transmembrane protein BRI(gene name synonym)	psi-mi:purb_rat(display_long)|uniprotkb:Purb(gene name)|psi-mi:Purb(display_short)|uniprotkb:Purine-rich element-binding protein B(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Martins et al. (2018)	imex:IM-28469|pubmed:29476059	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26440627|imex:IM-28469-5	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSRNOG00000016271(gene)|ensembl:ENSRNOT00000023037(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001540"(amyloid-beta binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0010008"(endosome membrane)|go:"GO:0030660"(Golgi-associated vesicle membrane)|go:"GO:0031301"(integral component of organelle membrane)|go:"GO:0042985"(negative regulation of amyloid precursor protein biosynthetic process)|interpro:IPR007084(BRICHOS)|interpro:IPR040145|mint:Q5XIE8|refseq:NP_001006964.1|rgd:620727	go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0046332"(SMAD binding)|go:"GO:0140297"(DNA-binding transcription factor binding)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000900"(translation repressor activity, mRNA regulatory element binding)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0008283"(cell population proliferation)|go:"GO:0030154"(cell differentiation)|go:"GO:0032422"(purine-rich negative regulatory element binding)|mint:Q68A21|refseq:NP_001017503.1|interpro:IPR006628(PUR-alpha/beta/gamma, DNA/RNA-binding)|interpro:IPR030499|rgd:1559465	-	-	-	figure legend:st1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10116(rat-hippocampus)|taxid:10116(Rattus norvegicus hippocampal neurons)	-	2020/10/30	2020/10/30	rogid:DtE+ZXAZKdCMvUW5K+jXQ5bH07M10116	rogid:C/1C29JkX6J5Sb4qhdTIrNfNsAQ10116	rigid:zzsc1zNhBb5nwIRPeFpYOKgC3M8	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q5XIE8	uniprotkb:Q05546	intact:EBI-15348306|ensembl:ENSRNOP00000023037	intact:EBI-1039732	psi-mi:itm2b_rat(display_long)|uniprotkb:Itm2b(gene name)|psi-mi:Itm2b(display_short)|uniprotkb:Immature BRI2(gene name synonym)|uniprotkb:Transmembrane protein BRI(gene name synonym)	psi-mi:tenr_rat(display_long)|uniprotkb:Tnr(gene name)|psi-mi:Tnr(display_short)|uniprotkb:Restrictin(gene name synonym)|uniprotkb:Janusin(gene name synonym)|uniprotkb:Neural recognition molecule J1-160/180(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Martins et al. (2018)	imex:IM-28469|pubmed:29476059	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26440627|imex:IM-28469-5	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSRNOG00000016271(gene)|ensembl:ENSRNOT00000023037(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001540"(amyloid-beta binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0010008"(endosome membrane)|go:"GO:0030660"(Golgi-associated vesicle membrane)|go:"GO:0031301"(integral component of organelle membrane)|go:"GO:0042985"(negative regulation of amyloid precursor protein biosynthetic process)|interpro:IPR007084(BRICHOS)|interpro:IPR040145|mint:Q5XIE8|refseq:NP_001006964.1|rgd:620727	rgd:3886|refseq:NP_037177.1|interpro:IPR002181(Fibrinogen, alpha/beta/gamma chain, C-terminal globular)|interpro:IPR003961(Fibronectin, type III)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR033079|interpro:IPR014716(Fibrinogen, alpha/beta/gamma chain, C-terminal globular, subdomain 1)|mint:Q05546|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005178"(integrin binding)|go:"GO:0005615"(extracellular space)|go:"GO:0007155"(cell adhesion)|go:"GO:0007158"(neuron cell-cell adhesion)|go:"GO:0007162"(negative regulation of cell adhesion)|go:"GO:0007399"(nervous system development)|go:"GO:0008306"(associative learning)|go:"GO:0009986"(cell surface)|go:"GO:0010977"(negative regulation of neuron projection development)|go:"GO:0022029"(telencephalon cell migration)|go:"GO:0022408"(negative regulation of cell-cell adhesion)|go:"GO:0030198"(extracellular matrix organization)|go:"GO:0030517"(negative regulation of axon extension)|go:"GO:0031012"(extracellular matrix)|go:"GO:0035641"(locomotory exploration behavior)|go:"GO:0045121"(membrane raft)|go:"GO:0048692"(negative regulation of axon extension involved in regeneration)|go:"GO:0050804"(modulation of chemical synaptic transmission)|go:"GO:0050805"(negative regulation of synaptic transmission)|go:"GO:0050808"(synapse organization)|go:"GO:0050885"(neuromuscular process controlling balance)|go:"GO:0051968"(positive regulation of synaptic transmission, glutamatergic)|go:"GO:0051971"(positive regulation of transmission of nerve impulse)|go:"GO:0060291"(long-term synaptic potentiation)|go:"GO:0062023"(collagen-containing extracellular matrix)|go:"GO:0072534"(perineuronal net)|go:"GO:0098685"(Schaffer collateral - CA1 synapse)|go:"GO:0098686"(hippocampal mossy fiber to CA3 synapse)|go:"GO:0098966"(perisynaptic extracellular matrix)|go:"GO:0098978"(glutamatergic synapse)|rcsb pdb:1TDQ|reactome:R-RNO-3000178|interpro:IPR000742(EGF-like, type 3)|interpro:IPR036056|interpro:IPR036116|interpro:IPR041161	-	-	-	figure legend:st1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10116(rat-hippocampus)|taxid:10116(Rattus norvegicus hippocampal neurons)	-	2020/10/30	2020/10/30	rogid:DtE+ZXAZKdCMvUW5K+jXQ5bH07M10116	rogid:Z810KbeOItf8zwgtic+nWX8azEM10116	rigid:zzsc1zNhBb5nwIRPeFpYOKgC3M8	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q5XIE8	uniprotkb:Q68FQ0	intact:EBI-15348306|ensembl:ENSRNOP00000023037	intact:EBI-931470|uniprotkb:Q6PCT4|ensembl:ENSRNOP00000015886	psi-mi:itm2b_rat(display_long)|uniprotkb:Itm2b(gene name)|psi-mi:Itm2b(display_short)|uniprotkb:Immature BRI2(gene name synonym)|uniprotkb:Transmembrane protein BRI(gene name synonym)	psi-mi:tcpe_rat(display_long)|uniprotkb:Cct5(gene name)|psi-mi:Cct5(display_short)|uniprotkb:CCT-epsilon(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Martins et al. (2018)	imex:IM-28469|pubmed:29476059	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26440627|imex:IM-28469-5	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSRNOG00000016271(gene)|ensembl:ENSRNOT00000023037(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001540"(amyloid-beta binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0010008"(endosome membrane)|go:"GO:0030660"(Golgi-associated vesicle membrane)|go:"GO:0031301"(integral component of organelle membrane)|go:"GO:0042985"(negative regulation of amyloid precursor protein biosynthetic process)|interpro:IPR007084(BRICHOS)|interpro:IPR040145|mint:Q5XIE8|refseq:NP_001006964.1|rgd:620727	rgd:735161|refseq:NP_001004078.1|ensembl:ENSRNOG00000011632(gene)|ensembl:ENSRNOT00000015886(transcript)|go:"GO:0003730"(mRNA 3'-UTR binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005813"(centrosome)|go:"GO:0005832"(chaperonin-containing T-complex)|go:"GO:0005874"(microtubule)|go:"GO:0006457"(protein folding)|go:"GO:0007339"(binding of sperm to zona pellucida)|go:"GO:0009615"(response to virus)|go:"GO:0031681"(G-protein beta-subunit binding)|go:"GO:0032212"(positive regulation of telomere maintenance via telomerase)|go:"GO:0044183"(protein folding chaperone)|go:"GO:0044297"(cell body)|go:"GO:0048027"(mRNA 5'-UTR binding)|go:"GO:0048487"(beta-tubulin binding)|go:"GO:0050821"(protein stabilization)|go:"GO:0051082"(unfolded protein binding)|go:"GO:1901998"(toxin transport)|go:"GO:1904851"(positive regulation of establishment of protein localization to telomere)|interpro:IPR002194(Chaperonin TCP-1, conserved site)|interpro:IPR002423(Chaperonin Cpn60/TCP-1)|interpro:IPR012718(T-complex protein 1, epsilon subunit)|interpro:IPR017998|interpro:IPR027409|interpro:IPR027410|interpro:IPR027413|mint:Q68FQ0|reactome:R-RNO-390471|reactome:R-RNO-5620922|reactome:R-RNO-6814122	-	-	-	figure legend:st1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10116(rat-hippocampus)|taxid:10116(Rattus norvegicus hippocampal neurons)	-	2020/10/30	2020/10/30	rogid:DtE+ZXAZKdCMvUW5K+jXQ5bH07M10116	rogid:ABW24Esuv9oCZYZr+++2wlVSTcI10116	rigid:zzsc1zNhBb5nwIRPeFpYOKgC3M8	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q5XIE8	uniprotkb:P61265	intact:EBI-15348306|ensembl:ENSRNOP00000023037	intact:EBI-2255905|uniprotkb:P32853|ensembl:ENSRNOP00000026063	psi-mi:itm2b_rat(display_long)|uniprotkb:Itm2b(gene name)|psi-mi:Itm2b(display_short)|uniprotkb:Immature BRI2(gene name synonym)|uniprotkb:Transmembrane protein BRI(gene name synonym)	psi-mi:stx1b_rat(display_long)|uniprotkb:Stx1b(gene name)|psi-mi:Stx1b(display_short)|uniprotkb:Stx1b2(gene name synonym)|uniprotkb:Syntaxin-1B2(gene name synonym)|uniprotkb:P35B(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Martins et al. (2018)	imex:IM-28469|pubmed:29476059	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26440627|imex:IM-28469-5	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSRNOG00000016271(gene)|ensembl:ENSRNOT00000023037(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001540"(amyloid-beta binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0010008"(endosome membrane)|go:"GO:0030660"(Golgi-associated vesicle membrane)|go:"GO:0031301"(integral component of organelle membrane)|go:"GO:0042985"(negative regulation of amyloid precursor protein biosynthetic process)|interpro:IPR007084(BRICHOS)|interpro:IPR040145|mint:Q5XIE8|refseq:NP_001006964.1|rgd:620727	rgd:3784|refseq:NP_036832.1|go:"GO:0016079"(synaptic vesicle exocytosis)|go:"GO:0016081"(synaptic vesicle docking)|go:"GO:0016192"(vesicle-mediated transport)|go:"GO:0017157"(regulation of exocytosis)|go:"GO:0019901"(protein kinase binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030424"(axon)|go:"GO:0031201"(SNARE complex)|go:"GO:0031594"(neuromuscular junction)|go:"GO:0031629"(synaptic vesicle fusion to presynaptic active zone membrane)|go:"GO:0042734"(presynaptic membrane)|go:"GO:0048278"(vesicle docking)|go:"GO:0048787"(presynaptic active zone membrane)|go:"GO:0048791"(calcium ion-regulated exocytosis of neurotransmitter)|go:"GO:0060025"(regulation of synaptic activity)|go:"GO:0061669"(spontaneous neurotransmitter secretion)|go:"GO:0072657"(protein localization to membrane)|go:"GO:0098793"(presynapse)|go:"GO:0098967"(exocytic insertion of neurotransmitter receptor to postsynaptic membrane)|go:"GO:1903422"(negative regulation of synaptic vesicle recycling)|go:"GO:1904050"(positive regulation of spontaneous neurotransmitter secretion)|go:"GO:1905302"(negative regulation of macropinocytosis)|go:"GO:2000463"(positive regulation of excitatory postsynaptic potential)|interpro:IPR000727(Target SNARE coiled-coil region)|interpro:IPR006011(Syntaxin, N-terminal)|interpro:IPR006012(Syntaxin/epimorphin, conserved site)|interpro:IPR010989(t-SNARE)|interpro:IPR028669|mint:P61265|reactome:R-RNO-5682910|ensembl:ENSRNOG00000019193(gene)|ensembl:ENSRNOT00000026063(transcript)|go:"GO:0000149"(SNARE binding)|go:"GO:0001956"(positive regulation of neurotransmitter secretion)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005484"(SNAP receptor activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006887"(exocytosis)|go:"GO:0006904"(vesicle docking involved in exocytosis)|go:"GO:0006906"(vesicle fusion)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0010807"(regulation of synaptic vesicle priming)|go:"GO:0010977"(negative regulation of neuron projection development)|go:"GO:0012505"(endomembrane system)|go:"GO:0015031"(protein transport)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)	-	-	-	figure legend:st1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10116(rat-hippocampus)|taxid:10116(Rattus norvegicus hippocampal neurons)	-	2020/10/30	2020/10/30	rogid:DtE+ZXAZKdCMvUW5K+jXQ5bH07M10116	rogid:B3aWVxxX3lZ8hOYK4gxwZupY7g410116	rigid:zzsc1zNhBb5nwIRPeFpYOKgC3M8	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q5XIE8	uniprotkb:P21707	intact:EBI-15348306|ensembl:ENSRNOP00000023037	intact:EBI-458098|uniprotkb:Q3S2E6|uniprotkb:Q707P5|ensembl:ENSRNOP00000049624|ensembl:ENSRNOP00000069194	psi-mi:itm2b_rat(display_long)|uniprotkb:Itm2b(gene name)|psi-mi:Itm2b(display_short)|uniprotkb:Immature BRI2(gene name synonym)|uniprotkb:Transmembrane protein BRI(gene name synonym)	psi-mi:syt1_rat(display_long)|uniprotkb:Syt1(gene name)|psi-mi:Syt1(display_short)|uniprotkb:Synaptotagmin I(gene name synonym)|uniprotkb:p65(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Martins et al. (2018)	imex:IM-28469|pubmed:29476059	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26440627|imex:IM-28469-5	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSRNOG00000016271(gene)|ensembl:ENSRNOT00000023037(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001540"(amyloid-beta binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0010008"(endosome membrane)|go:"GO:0030660"(Golgi-associated vesicle membrane)|go:"GO:0031301"(integral component of organelle membrane)|go:"GO:0042985"(negative regulation of amyloid precursor protein biosynthetic process)|interpro:IPR007084(BRICHOS)|interpro:IPR040145|mint:Q5XIE8|refseq:NP_001006964.1|rgd:620727	rgd:3803|refseq:NP_001028852.2|ensembl:ENSRNOG00000006426(gene)|ensembl:ENSRNOT00000048880(transcript)|ensembl:ENSRNOT00000088950(transcript)|go:"GO:0000149"(SNARE binding)|go:"GO:0001786"(phosphatidylserine binding)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005513"(detection of calcium ion)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005543"(phospholipid binding)|go:"GO:0005544"(calcium-dependent phospholipid binding)|go:"GO:0005546"(phosphatidylinositol-4,5-bisphosphate binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0007269"(neurotransmitter secretion)|go:"GO:0007420"(brain development)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0014059"(regulation of dopamine secretion)|go:"GO:0016079"(synaptic vesicle exocytosis)|go:"GO:0016192"(vesicle-mediated transport)|go:"GO:0017075"(syntaxin-1 binding)|go:"GO:0017156"(calcium-ion regulated exocytosis)|go:"GO:0017158"(regulation of calcium ion-dependent exocytosis)|go:"GO:0019905"(syntaxin binding)|go:"GO:0030141"(secretory granule)|go:"GO:0030154"(cell differentiation)|go:"GO:0030276"(clathrin binding)|go:"GO:0030285"(integral component of synaptic vesicle membrane)|go:"GO:0030348"(syntaxin-3 binding)|go:"GO:0030424"(axon)|go:"GO:0030672"(synaptic vesicle membrane)|go:"GO:0031045"(dense core granule)|go:"GO:0031340"(positive regulation of vesicle fusion)|go:"GO:0033603"(positive regulation of dopamine secretion)|go:"GO:0042584"(chromaffin granule membrane)|go:"GO:0042734"(presynaptic membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0043005"(neuron projection)|go:"GO:0043195"(terminal bouton)|go:"GO:0043229"(intracellular organelle)|go:"GO:0044306"(neuron projection terminus)|go:"GO:0045956"(positive regulation of calcium ion-dependent exocytosis)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0048278"(vesicle docking)|go:"GO:0048306"(calcium-dependent protein binding)|go:"GO:0048488"(synaptic vesicle endocytosis)|go:"GO:0048791"(calcium ion-regulated exocytosis of neurotransmitter)|go:"GO:0050750"(low-density lipoprotein particle receptor binding)|go:"GO:0050806"(positive regulation of synaptic transmission)|go:"GO:0051291"(protein heterooligomerization)|go:"GO:0051592"(response to calcium ion)|go:"GO:0051966"(regulation of synaptic transmission, glutamatergic)|go:"GO:0060076"(excitatory synapse)|go:"GO:0061669"(spontaneous neurotransmitter secretion)|go:"GO:0061891"(calcium ion sensor activity)|go:"GO:0070382"(exocytic vesicle)|go:"GO:0071277"(cellular response to calcium ion)|go:"GO:0071911"(synchronous neurotransmitter secretion)|go:"GO:0098686"(hippocampal mossy fiber to CA3 synapse)|go:"GO:0098746"(fast, calcium ion-dependent exocytosis of neurotransmitter)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099502"(calcium-dependent activation of synaptic vesicle fusion)|go:"GO:1903235"(positive regulation of calcium ion-dependent exocytosis of neurotransmitter)|go:"GO:1903305"(regulation of regulated secretory pathway)|go:"GO:1903861"(positive regulation of dendrite extension)|go:"GO:2000300"(regulation of synaptic vesicle exocytosis)|interpro:IPR000008(C2 calcium-dependent membrane targeting)|interpro:IPR001565(Synaptotagmin)|interpro:IPR015428(Synaptotagmin 1,2)|interpro:IPR035892|mint:P21707|rcsb pdb:1BYN|rcsb pdb:1K5W|rcsb pdb:1RSY|rcsb pdb:1TJM|rcsb pdb:1TJX|rcsb pdb:1UOV|rcsb pdb:1UOW|rcsb pdb:2YOA|rcsb pdb:4WEE|rcsb pdb:5CCG|rcsb pdb:5CCH|rcsb pdb:5CCI|rcsb pdb:5CCJ|rcsb pdb:5KJ7|rcsb pdb:5KJ8|rcsb pdb:5W5C|rcsb pdb:5W5D|rcsb pdb:6CXW|rcsb pdb:6MTI|reactome:R-RNO-181429|reactome:R-RNO-181430|reactome:R-RNO-210500|reactome:R-RNO-212676|reactome:R-RNO-264642|reactome:R-RNO-8856825|reactome:R-RNO-8856828|reactome:R-RNO-888590|refseq:XP_017450168.1|dip:DIP-29064N	-	-	-	figure legend:st1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10116(rat-hippocampus)|taxid:10116(Rattus norvegicus hippocampal neurons)	-	2020/10/30	2020/10/30	rogid:DtE+ZXAZKdCMvUW5K+jXQ5bH07M10116	rogid:fr7zfj22zAOY/bJ7psjrgnsb0g810116	rigid:zzsc1zNhBb5nwIRPeFpYOKgC3M8	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q5XIE8	uniprotkb:Q02563	intact:EBI-15348306|ensembl:ENSRNOP00000023037	intact:EBI-466194|uniprotkb:Q58DZ8|ensembl:ENSRNOP00000028760	psi-mi:itm2b_rat(display_long)|uniprotkb:Itm2b(gene name)|psi-mi:Itm2b(display_short)|uniprotkb:Immature BRI2(gene name synonym)|uniprotkb:Transmembrane protein BRI(gene name synonym)	psi-mi:sv2a_rat(display_long)|uniprotkb:Sv2a(gene name)|psi-mi:Sv2a(display_short)|uniprotkb:Sv2(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Martins et al. (2018)	imex:IM-28469|pubmed:29476059	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26440627|imex:IM-28469-5	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSRNOG00000016271(gene)|ensembl:ENSRNOT00000023037(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001540"(amyloid-beta binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0010008"(endosome membrane)|go:"GO:0030660"(Golgi-associated vesicle membrane)|go:"GO:0031301"(integral component of organelle membrane)|go:"GO:0042985"(negative regulation of amyloid precursor protein biosynthetic process)|interpro:IPR007084(BRICHOS)|interpro:IPR040145|mint:Q5XIE8|refseq:NP_001006964.1|rgd:620727	rgd:619715|refseq:NP_476558.2|refseq:XP_006233014.1|ensembl:ENSRNOT00000028760(transcript)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005911"(cell-cell junction)|go:"GO:0006836"(neurotransmitter transport)|go:"GO:0006874"(cellular calcium ion homeostasis)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0014052"(regulation of gamma-aminobutyric acid secretion)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016082"(synaptic vesicle priming)|go:"GO:0019901"(protein kinase binding)|go:"GO:0022857"(transmembrane transporter activity)|go:"GO:0030285"(integral component of synaptic vesicle membrane)|go:"GO:0030425"(dendrite)|go:"GO:0030672"(synaptic vesicle membrane)|go:"GO:0031594"(neuromuscular junction)|go:"GO:0043005"(neuron projection)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043195"(terminal bouton)|go:"GO:0045202"(synapse)|go:"GO:0048786"(presynaptic active zone)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0098982"(GABA-ergic synapse)|interpro:IPR001646(Pentapeptide repeat)|interpro:IPR005828(General substrate transporter)|interpro:IPR005829(Sugar transporter, conserved site)|interpro:IPR011701(Major facilitator superfamily MFS-1)|interpro:IPR020846|interpro:IPR022308|interpro:IPR036259|mint:Q02563|ensembl:ENSRNOG00000021182(gene)	-	-	-	figure legend:st1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10116(rat-hippocampus)|taxid:10116(Rattus norvegicus hippocampal neurons)	-	2020/10/30	2020/10/30	rogid:DtE+ZXAZKdCMvUW5K+jXQ5bH07M10116	rogid:a7TA6gTNT5eWAIVLxjT1dgUQzn410116	rigid:zzsc1zNhBb5nwIRPeFpYOKgC3M8	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q5XIE8	uniprotkb:P16086	intact:EBI-15348306|ensembl:ENSRNOP00000023037	intact:EBI-2255997|uniprotkb:O88663|uniprotkb:P70477|ensembl:ENSRNOP00000042382	psi-mi:itm2b_rat(display_long)|uniprotkb:Itm2b(gene name)|psi-mi:Itm2b(display_short)|uniprotkb:Immature BRI2(gene name synonym)|uniprotkb:Transmembrane protein BRI(gene name synonym)	psi-mi:sptn1_rat(display_long)|uniprotkb:Sptan1(gene name)|psi-mi:Sptan1(display_short)|uniprotkb:Spna2(gene name synonym)|uniprotkb:Spta2(gene name synonym)|uniprotkb:Alpha-II spectrin(gene name synonym)|uniprotkb:Fodrin alpha chain(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Martins et al. (2018)	imex:IM-28469|pubmed:29476059	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26440627|imex:IM-28469-5	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSRNOG00000016271(gene)|ensembl:ENSRNOT00000023037(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001540"(amyloid-beta binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0010008"(endosome membrane)|go:"GO:0030660"(Golgi-associated vesicle membrane)|go:"GO:0031301"(integral component of organelle membrane)|go:"GO:0042985"(negative regulation of amyloid precursor protein biosynthetic process)|interpro:IPR007084(BRICHOS)|interpro:IPR040145|mint:Q5XIE8|refseq:NP_001006964.1|rgd:620727	rgd:621714|refseq:NP_741984.2|ensembl:ENSRNOG00000015396(gene)|ensembl:ENSRNOT00000045827(transcript)|go:"GO:0003779"(actin binding)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005916"(fascia adherens)|go:"GO:0008091"(spectrin)|go:"GO:0016020"(membrane)|go:"GO:0016328"(lateral plasma membrane)|go:"GO:0019905"(syntaxin binding)|go:"GO:0030018"(Z disc)|go:"GO:0030507"(spectrin binding)|go:"GO:0030863"(cortical cytoskeleton)|go:"GO:0031532"(actin cytoskeleton reorganization)|go:"GO:0032437"(cuticular plate)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033270"(paranode region of axon)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0051693"(actin filament capping)|interpro:IPR001452(Src homology-3)|interpro:IPR002017(Spectrin repeat)|interpro:IPR002048(Calcium-binding EF-hand)|interpro:IPR011992(EF-Hand type)|interpro:IPR014837(EF-hand, Ca insensitive)|interpro:IPR018159|interpro:IPR018247|interpro:IPR035825|interpro:IPR036028|mint:P16086|rcsb pdb:3THK|reactome:R-RNO-264870|reactome:R-RNO-375165|reactome:R-RNO-445095|reactome:R-RNO-5673001|reactome:R-RNO-6798695|reactome:R-RNO-6807878|reactome:R-RNO-9013420|reactome:R-RNO-9013424	-	-	-	figure legend:st1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10116(rat-hippocampus)|taxid:10116(Rattus norvegicus hippocampal neurons)	-	2020/10/30	2020/10/30	rogid:DtE+ZXAZKdCMvUW5K+jXQ5bH07M10116	rogid:3Tj95Pgv62omEnsaMAG3bfLLXsM10116	rigid:zzsc1zNhBb5nwIRPeFpYOKgC3M8	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q5XIE8	uniprotkb:P12346	intact:EBI-15348306|ensembl:ENSRNOP00000023037	intact:EBI-5748069|uniprotkb:Q63602|uniprotkb:Q64628|uniprotkb:Q64630|uniprotkb:Q7TNX0|ensembl:ENSRNOP00000045637	psi-mi:itm2b_rat(display_long)|uniprotkb:Itm2b(gene name)|psi-mi:Itm2b(display_short)|uniprotkb:Immature BRI2(gene name synonym)|uniprotkb:Transmembrane protein BRI(gene name synonym)	psi-mi:trfe_rat(display_long)|uniprotkb:Tf(gene name)|psi-mi:Tf(display_short)|uniprotkb:Beta-1 metal-binding globulin(gene name synonym)|uniprotkb:Liver regeneration-related protein LRRG03(gene name synonym)|uniprotkb:Siderophilin(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Martins et al. (2018)	imex:IM-28469|pubmed:29476059	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26440627|imex:IM-28469-5	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSRNOG00000016271(gene)|ensembl:ENSRNOT00000023037(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001540"(amyloid-beta binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0010008"(endosome membrane)|go:"GO:0030660"(Golgi-associated vesicle membrane)|go:"GO:0031301"(integral component of organelle membrane)|go:"GO:0042985"(negative regulation of amyloid precursor protein biosynthetic process)|interpro:IPR007084(BRICHOS)|interpro:IPR040145|mint:Q5XIE8|refseq:NP_001006964.1|rgd:620727	rgd:3845|refseq:NP_001013128.1|ensembl:ENSRNOG00000030625(gene)|ensembl:ENSRNOT00000045628(transcript)|go:"GO:0001666"(response to hypoxia)|go:"GO:0005576"(extracellular region)|go:"GO:0005604"(basement membrane)|go:"GO:0005615"(extracellular space)|go:"GO:0005768"(endosome)|go:"GO:0005769"(early endosome)|go:"GO:0005770"(late endosome)|go:"GO:0005886"(plasma membrane)|go:"GO:0005905"(clathrin-coated pit)|go:"GO:0006826"(iron ion transport)|go:"GO:0006879"(cellular iron ion homeostasis)|go:"GO:0006915"(apoptotic process)|go:"GO:0006953"(acute-phase response)|go:"GO:0007015"(actin filament organization)|go:"GO:0007257"(obsolete activation of JUN kinase activity)|go:"GO:0008198"(ferrous iron binding)|go:"GO:0008199"(ferric iron binding)|go:"GO:0009617"(response to bacterium)|go:"GO:0009925"(basal plasma membrane)|go:"GO:0009986"(cell surface)|go:"GO:0010288"(response to lead ion)|go:"GO:0014070"(response to organic cyclic compound)|go:"GO:0016020"(membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0019731"(antibacterial humoral response)|go:"GO:0030139"(endocytic vesicle)|go:"GO:0030316"(osteoclast differentiation)|go:"GO:0031232"(extrinsic component of external side of plasma membrane)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0031643"(positive regulation of myelination)|go:"GO:0031982"(vesicle)|go:"GO:0034756"(regulation of iron ion transport)|go:"GO:0034986"(iron chaperone activity)|go:"GO:0042327"(positive regulation of phosphorylation)|go:"GO:0045178"(basal part of cell)|go:"GO:0045780"(positive regulation of bone resorption)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0048260"(positive regulation of receptor-mediated endocytosis)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051286"(cell tip)|go:"GO:0055037"(recycling endosome)|go:"GO:0060395"(SMAD protein signal transduction)|go:"GO:0070371"(ERK1 and ERK2 cascade)|go:"GO:0070447"(positive regulation of oligodendrocyte progenitor proliferation)|go:"GO:0071281"(cellular response to iron ion)|go:"GO:0071320"(cellular response to cAMP)|go:"GO:0071372"(cellular response to follicle-stimulating hormone stimulus)|go:"GO:1990459"(transferrin receptor binding)|go:"GO:1990712"(HFE-transferrin receptor complex)|go:"GO:2000147"(positive regulation of cell motility)|interpro:IPR001156(Peptidase S60, transferrin lactoferrin)|interpro:IPR016357(Transferrin)|interpro:IPR018195|interpro:IPR030685|mint:P12346|reactome:R-RNO-114608|reactome:R-RNO-381426|reactome:R-RNO-8856825|reactome:R-RNO-8856828|reactome:R-RNO-8957275|reactome:R-RNO-917937|reactome:R-RNO-917977	-	-	-	figure legend:st1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10116(rat-hippocampus)|taxid:10116(Rattus norvegicus hippocampal neurons)	-	2020/10/30	2020/10/30	rogid:DtE+ZXAZKdCMvUW5K+jXQ5bH07M10116	rogid:9b+8HnYQbOkvBtuNUgHzhq2+cQ010116	rigid:zzsc1zNhBb5nwIRPeFpYOKgC3M8	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q5XIE8	uniprotkb:Q6RJR6	intact:EBI-15348306|ensembl:ENSRNOP00000023037	intact:EBI-919246|uniprotkb:Q6P6R3|uniprotkb:Q8VBU0|ensembl:ENSRNOP00000028785	psi-mi:itm2b_rat(display_long)|uniprotkb:Itm2b(gene name)|psi-mi:Itm2b(display_short)|uniprotkb:Immature BRI2(gene name synonym)|uniprotkb:Transmembrane protein BRI(gene name synonym)	psi-mi:rtn3_rat(display_long)|uniprotkb:Rtn3(gene name)|psi-mi:Rtn3(display_short)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Martins et al. (2018)	imex:IM-28469|pubmed:29476059	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26440627|imex:IM-28469-5	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSRNOG00000016271(gene)|ensembl:ENSRNOT00000023037(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001540"(amyloid-beta binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0010008"(endosome membrane)|go:"GO:0030660"(Golgi-associated vesicle membrane)|go:"GO:0031301"(integral component of organelle membrane)|go:"GO:0042985"(negative regulation of amyloid precursor protein biosynthetic process)|interpro:IPR007084(BRICHOS)|interpro:IPR040145|mint:Q5XIE8|refseq:NP_001006964.1|rgd:620727	rgd:620988|refseq:NP_001009953.2|refseq:NP_543185.2|ensembl:ENSRNOG00000021202(gene)|ensembl:ENSRNOT00000028785(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0006915"(apoptotic process)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016192"(vesicle-mediated transport)|go:"GO:0045202"(synapse)|go:"GO:0071786"(endoplasmic reticulum tubular network organization)|go:"GO:0071787"(endoplasmic reticulum tubular network formation)|go:"GO:1902430"(negative regulation of amyloid-beta formation)|interpro:IPR003388(Reticulon)|mint:Q6RJR6|reactome:R-RNO-8849932	-	-	-	figure legend:st1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10116(rat-hippocampus)|taxid:10116(Rattus norvegicus hippocampal neurons)	-	2020/10/30	2020/10/30	rogid:DtE+ZXAZKdCMvUW5K+jXQ5bH07M10116	rogid:CehbzFUmpJjUrA42+RLJ+oKmx3A10116	rigid:zzsc1zNhBb5nwIRPeFpYOKgC3M8	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q5XIE8	uniprotkb:Q64548	intact:EBI-15348306|ensembl:ENSRNOP00000023037	intact:EBI-26437852|uniprotkb:Q64547	psi-mi:itm2b_rat(display_long)|uniprotkb:Itm2b(gene name)|psi-mi:Itm2b(display_short)|uniprotkb:Immature BRI2(gene name synonym)|uniprotkb:Transmembrane protein BRI(gene name synonym)	psi-mi:rtn1_rat(display_long)|uniprotkb:Rtn1(gene name)|psi-mi:Rtn1(display_short)|uniprotkb:Nsp(gene name synonym)|uniprotkb:Neuroendocrine-specific protein(gene name synonym)|uniprotkb:S-rex(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Martins et al. (2018)	imex:IM-28469|pubmed:29476059	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26440627|imex:IM-28469-5	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSRNOG00000016271(gene)|ensembl:ENSRNOT00000023037(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001540"(amyloid-beta binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0010008"(endosome membrane)|go:"GO:0030660"(Golgi-associated vesicle membrane)|go:"GO:0031301"(integral component of organelle membrane)|go:"GO:0042985"(negative regulation of amyloid precursor protein biosynthetic process)|interpro:IPR007084(BRICHOS)|interpro:IPR040145|mint:Q5XIE8|refseq:NP_001006964.1|rgd:620727	go:"GO:0000139"(Golgi membrane)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005790"(smooth endoplasmic reticulum)|go:"GO:0016021"(integral component of membrane)|go:"GO:1902430"(negative regulation of amyloid-beta formation)|mint:Q64548|refseq:NP_446317.1|refseq:XP_008762912.1|interpro:IPR003388(Reticulon)|rgd:620986	-	-	-	figure legend:st1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10116(rat-hippocampus)|taxid:10116(Rattus norvegicus hippocampal neurons)	-	2020/10/30	2020/10/30	rogid:DtE+ZXAZKdCMvUW5K+jXQ5bH07M10116	rogid:GR15tCaopATHPIxGwl20b04sG4c10116	rigid:zzsc1zNhBb5nwIRPeFpYOKgC3M8	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q5XIE8	uniprotkb:P63012	intact:EBI-15348306|ensembl:ENSRNOP00000023037	intact:EBI-440126|ensembl:ENSRNOP00000026392|uniprotkb:P05713	psi-mi:itm2b_rat(display_long)|uniprotkb:Itm2b(gene name)|psi-mi:Itm2b(display_short)|uniprotkb:Immature BRI2(gene name synonym)|uniprotkb:Transmembrane protein BRI(gene name synonym)	psi-mi:rab3a_rat(display_long)|uniprotkb:Rab3a(gene name)|psi-mi:Rab3a(display_short)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Martins et al. (2018)	imex:IM-28469|pubmed:29476059	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26440627|imex:IM-28469-5	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSRNOG00000016271(gene)|ensembl:ENSRNOT00000023037(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001540"(amyloid-beta binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0010008"(endosome membrane)|go:"GO:0030660"(Golgi-associated vesicle membrane)|go:"GO:0031301"(integral component of organelle membrane)|go:"GO:0042985"(negative regulation of amyloid precursor protein biosynthetic process)|interpro:IPR007084(BRICHOS)|interpro:IPR040145|mint:Q5XIE8|refseq:NP_001006964.1|rgd:620727	ensembl:ENSRNOT00000026391(transcript)|go:"GO:0001669"(acrosomal vesicle)|go:"GO:0001671"(ATPase activator activity)|go:"GO:0001778"(plasma membrane repair)|go:"GO:0003016"(respiratory system process)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005764"(lysosome)|go:"GO:0005768"(endosome)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006887"(exocytosis)|go:"GO:0006904"(vesicle docking involved in exocytosis)|go:"GO:0007005"(mitochondrion organization)|go:"GO:0007274"(neuromuscular synaptic transmission)|go:"GO:0007409"(axonogenesis)|ensembl:ENSRNOG00000019433(gene)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0009306"(protein secretion)|go:"GO:0009791"(post-embryonic development)|go:"GO:0010807"(regulation of synaptic vesicle priming)|go:"GO:0014059"(regulation of dopamine secretion)|go:"GO:0016020"(membrane)|go:"GO:0016079"(synaptic vesicle exocytosis)|go:"GO:0016188"(synaptic vesicle maturation)|go:"GO:0017156"(calcium-ion regulated exocytosis)|go:"GO:0017157"(regulation of exocytosis)|go:"GO:0030141"(secretory granule)|go:"GO:0030324"(lung development)|go:"GO:0030424"(axon)|go:"GO:0030742"(GTP-dependent protein binding)|go:"GO:0031489"(myosin V binding)|go:"GO:0031630"(regulation of synaptic vesicle fusion to presynaptic active zone membrane)|go:"GO:0032418"(lysosome localization)|go:"GO:0032482"(Rab protein signal transduction)|go:"GO:0032991"(protein-containing complex)|go:"GO:0036465"(synaptic vesicle recycling)|go:"GO:0043195"(terminal bouton)|go:"GO:0043229"(intracellular organelle)|go:"GO:0045055"(regulated exocytosis)|go:"GO:0048172"(regulation of short-term neuronal synaptic plasticity)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0048489"(synaptic vesicle transport)|go:"GO:0048786"(presynaptic active zone)|go:"GO:0048790"(maintenance of presynaptic active zone structure)|go:"GO:0050975"(sensory perception of touch)|go:"GO:0051021"(GDP-dissociation inhibitor binding)|go:"GO:0051117"(ATPase binding)|go:"GO:0060478"(acrosomal vesicle exocytosis)|go:"GO:0061670"(evoked neurotransmitter secretion)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0097091"(synaptic vesicle clustering)|go:"GO:0098993"(anchored component of synaptic vesicle membrane)|go:"GO:1903307"(positive regulation of regulated secretory pathway)|go:"GO:1905684"(regulation of plasma membrane repair)|go:"GO:2000300"(regulation of synaptic vesicle exocytosis)|interpro:IPR001806(Ras GTPase)|interpro:IPR005225(Small GTP-binding protein)|interpro:IPR027417|interpro:IPR037872|mint:P63012|rcsb pdb:1ZBD|rcsb pdb:3RAB|reactome:R-RNO-181429|reactome:R-RNO-181430|reactome:R-RNO-210500|reactome:R-RNO-212676|reactome:R-RNO-264642|reactome:R-RNO-6798695|reactome:R-RNO-8873719|reactome:R-RNO-8876198|reactome:R-RNO-888590|go:"GO:0051602"(response to electrical stimulus)|rgd:3528|refseq:NP_037150.2	-	-	-	figure legend:st1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10116(rat-hippocampus)|taxid:10116(Rattus norvegicus hippocampal neurons)	-	2020/10/30	2020/10/30	rogid:DtE+ZXAZKdCMvUW5K+jXQ5bH07M10116	rogid:Skrsn0x0LP/jAuOk1LQ4ataeiDA10116	rigid:zzsc1zNhBb5nwIRPeFpYOKgC3M8	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q5XIE8	uniprotkb:P63319	intact:EBI-15348306|ensembl:ENSRNOP00000023037	intact:EBI-12598030|ensembl:ENSRNOP00000071203|uniprotkb:P05697|uniprotkb:Q5FWS3	psi-mi:itm2b_rat(display_long)|uniprotkb:Itm2b(gene name)|psi-mi:Itm2b(display_short)|uniprotkb:Immature BRI2(gene name synonym)|uniprotkb:Transmembrane protein BRI(gene name synonym)	psi-mi:kpcg_rat(display_long)|uniprotkb:Prkcg(gene name)|psi-mi:Prkcg(display_short)|uniprotkb:Pkcc(gene name synonym)|uniprotkb:Pkcg(gene name synonym)|uniprotkb:Prkcc(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Martins et al. (2018)	imex:IM-28469|pubmed:29476059	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26440627|imex:IM-28469-5	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSRNOG00000016271(gene)|ensembl:ENSRNOT00000023037(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001540"(amyloid-beta binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0010008"(endosome membrane)|go:"GO:0030660"(Golgi-associated vesicle membrane)|go:"GO:0031301"(integral component of organelle membrane)|go:"GO:0042985"(negative regulation of amyloid precursor protein biosynthetic process)|interpro:IPR007084(BRICHOS)|interpro:IPR040145|mint:Q5XIE8|refseq:NP_001006964.1|rgd:620727	ensembl:ENSRNOG00000054371(gene)|ensembl:ENSRNOT00000080032(transcript)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0004697"(protein kinase C activity)|go:"GO:0004698"(calcium-dependent protein kinase C activity)|go:"GO:0004712"(protein serine/threonine/tyrosine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0007268"(chemical synaptic transmission)|go:"GO:0007611"(learning or memory)|go:"GO:0007635"(chemosensory behavior)|go:"GO:0008270"(zinc ion binding)|go:"GO:0009636"(response to toxic substance)|go:"GO:0014069"(postsynaptic density)|go:"GO:0016020"(membrane)|go:"GO:0016310"(phosphorylation)|go:"GO:0018105"(peptidyl-serine phosphorylation)|go:"GO:0030425"(dendrite)|go:"GO:0031397"(negative regulation of protein ubiquitination)|go:"GO:0032095"(regulation of response to food)|go:"GO:0032425"(positive regulation of mismatch repair)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0042177"(negative regulation of protein catabolic process)|go:"GO:0042752"(regulation of circadian rhythm)|go:"GO:0043005"(neuron projection)|go:"GO:0043278"(response to morphine)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0044305"(calyx of Held)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0048265"(response to pain)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0048511"(rhythmic process)|go:"GO:0050764"(regulation of phagocytosis)|go:"GO:0060291"(long-term synaptic potentiation)|go:"GO:0060384"(innervation)|go:"GO:0097060"(synaptic membrane)|go:"GO:0099171"(presynaptic modulation of chemical synaptic transmission)|go:"GO:0099523"(presynaptic cytosol)|go:"GO:0099524"(postsynaptic cytosol)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:1901799"(negative regulation of proteasomal protein catabolic process)|go:"GO:1990911"(response to psychosocial stress)|go:"GO:2000300"(regulation of synaptic vesicle exocytosis)|interpro:IPR000008(C2 calcium-dependent membrane targeting)|interpro:IPR000719(Protein kinase, core)|interpro:IPR000961(Protein kinase, C-terminal)|interpro:IPR002219(Protein kinase C, phorbol ester/diacylglycerol binding)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR014375(Protein kinase C, alpha/beta/gamma types)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR017892|interpro:IPR020454|interpro:IPR035892|mint:P63319|rcsb pdb:1TBN|rcsb pdb:1TBO|reactome:R-RNO-111933|reactome:R-RNO-114516|reactome:R-RNO-416993|reactome:R-RNO-5099900|reactome:R-RNO-76005|rgd:3397|refseq:NP_036760.1	-	-	-	figure legend:st1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10116(rat-hippocampus)|taxid:10116(Rattus norvegicus hippocampal neurons)	-	2020/10/30	2020/10/30	rogid:DtE+ZXAZKdCMvUW5K+jXQ5bH07M10116	rogid:t4ukCPPAnYUtHCH1hnQE+uiyfEM10116	rigid:zzsc1zNhBb5nwIRPeFpYOKgC3M8	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q5XIE8	uniprotkb:Q5XIH7	intact:EBI-15348306|ensembl:ENSRNOP00000023037	intact:EBI-918041|uniprotkb:P70629|uniprotkb:P70630|ensembl:ENSRNOP00000017472	psi-mi:itm2b_rat(display_long)|uniprotkb:Itm2b(gene name)|psi-mi:Itm2b(display_short)|uniprotkb:Immature BRI2(gene name synonym)|uniprotkb:Transmembrane protein BRI(gene name synonym)	psi-mi:phb2_rat(display_long)|uniprotkb:B-cell receptor-associated protein BAP37(gene name synonym)|uniprotkb:Phb2(gene name)|psi-mi:Phb2(display_short)|uniprotkb:Bcap37(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Martins et al. (2018)	imex:IM-28469|pubmed:29476059	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26440627|imex:IM-28469-5	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSRNOG00000016271(gene)|ensembl:ENSRNOT00000023037(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001540"(amyloid-beta binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0010008"(endosome membrane)|go:"GO:0030660"(Golgi-associated vesicle membrane)|go:"GO:0031301"(integral component of organelle membrane)|go:"GO:0042985"(negative regulation of amyloid precursor protein biosynthetic process)|interpro:IPR007084(BRICHOS)|interpro:IPR040145|mint:Q5XIE8|refseq:NP_001006964.1|rgd:620727	rgd:620203|refseq:NP_001013053.1|ensembl:ENSRNOG00000012999(gene)|ensembl:ENSRNOT00000017472(transcript)|go:"GO:0000423"(mitophagy)|go:"GO:0002639"(positive regulation of immunoglobulin production)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005886"(plasma membrane)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0007005"(mitochondrion organization)|go:"GO:0007062"(sister chromatid cohesion)|go:"GO:0007202"(activation of phospholipase C activity)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0009611"(response to wounding)|go:"GO:0009986"(cell surface)|go:"GO:0016363"(nuclear matrix)|go:"GO:0016477"(cell migration)|go:"GO:0023035"(CD40 signaling pathway)|go:"GO:0031536"(positive regulation of exit from mitosis)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033147"(negative regulation of intracellular estrogen receptor signaling pathway)|go:"GO:0033218"(amide binding)|go:"GO:0033600"(negative regulation of mammary gland epithelial cell proliferation)|go:"GO:0035632"(mitochondrial prohibitin complex)|go:"GO:0039520"(induction by virus of host autophagy)|go:"GO:0039529"(RIG-I signaling pathway)|go:"GO:0042113"(B cell activation)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043433"(negative regulation of DNA-binding transcription factor activity)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0046625"(sphingolipid binding)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0047485"(protein N-terminus binding)|go:"GO:0048786"(presynaptic active zone)|go:"GO:0050821"(protein stabilization)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0060744"(mammary gland branching involved in thelarche)|go:"GO:0060749"(mammary gland alveolus development)|go:"GO:0060762"(regulation of branching involved in mammary gland duct morphogenesis)|go:"GO:0070374"(positive regulation of ERK1 and ERK2 cascade)|go:"GO:0071300"(cellular response to retinoic acid)|go:"GO:0071456"(cellular response to hypoxia)|go:"GO:0071944"(cell periphery)|go:"GO:0098800"(inner mitochondrial membrane protein complex)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0098982"(GABA-ergic synapse)|go:"GO:0140374"(antiviral innate immune response)|go:"GO:1900208"(regulation of cardiolipin metabolic process)|go:"GO:1901224"(positive regulation of NIK/NF-kappaB signaling)|go:"GO:1902808"(positive regulation of cell cycle G1/S phase transition)|go:"GO:1904959"(regulation of cytochrome-c oxidase activity)|go:"GO:1990051"(activation of protein kinase C activity)|interpro:IPR000163(Prohibitin)|interpro:IPR001107(Band 7 protein)|interpro:IPR036013|mint:Q5XIH7|reactome:R-RNO-8949664|go:"GO:0014069"(postsynaptic density)	-	-	-	figure legend:st1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10116(rat-hippocampus)|taxid:10116(Rattus norvegicus hippocampal neurons)	-	2020/10/30	2020/10/30	rogid:DtE+ZXAZKdCMvUW5K+jXQ5bH07M10116	rogid:VjRorTWSSei7yX+hNlgLqK2S49810116	rigid:zzsc1zNhBb5nwIRPeFpYOKgC3M8	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q5XIE8	uniprotkb:P67779	intact:EBI-15348306|ensembl:ENSRNOP00000023037	intact:EBI-298513|uniprotkb:P24142|uniprotkb:Q4V8M6|ensembl:ENSRNOP00000066502	psi-mi:itm2b_rat(display_long)|uniprotkb:Itm2b(gene name)|psi-mi:Itm2b(display_short)|uniprotkb:Immature BRI2(gene name synonym)|uniprotkb:Transmembrane protein BRI(gene name synonym)	psi-mi:phb_rat(display_long)|uniprotkb:Phb(gene name)|psi-mi:Phb(display_short)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Martins et al. (2018)	imex:IM-28469|pubmed:29476059	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26440627|imex:IM-28469-5	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSRNOG00000016271(gene)|ensembl:ENSRNOT00000023037(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001540"(amyloid-beta binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0010008"(endosome membrane)|go:"GO:0030660"(Golgi-associated vesicle membrane)|go:"GO:0031301"(integral component of organelle membrane)|go:"GO:0042985"(negative regulation of amyloid precursor protein biosynthetic process)|interpro:IPR007084(BRICHOS)|interpro:IPR040145|mint:Q5XIE8|refseq:NP_001006964.1|rgd:620727	go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005737"(cytoplasm)|go:"GO:0005769"(early endosome)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0007005"(mitochondrion organization)|go:"GO:0007202"(activation of phospholipase C activity)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0009986"(cell surface)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010942"(positive regulation of cell death)|go:"GO:0010944"(negative regulation of transcription by competitive promoter binding)|go:"GO:0014069"(postsynaptic density)|go:"GO:0016575"(histone deacetylation)|go:"GO:0019899"(enzyme binding)|go:"GO:0023035"(CD40 signaling pathway)|go:"GO:0030061"(mitochondrial crista)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0031100"(animal organ regeneration)|go:"GO:0031315"(extrinsic component of mitochondrial outer membrane)|go:"GO:0031871"(proteinase activated receptor binding)|go:"GO:0032740"(positive regulation of interleukin-17 production)|go:"GO:0034097"(response to cytokine)|go:"GO:0035632"(mitochondrial prohibitin complex)|go:"GO:0035902"(response to immobilization stress)|go:"GO:0039529"(RIG-I signaling pathway)|go:"GO:0042113"(B cell activation)|go:"GO:0042177"(negative regulation of protein catabolic process)|go:"GO:0042493"|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043434"(response to peptide hormone)|go:"GO:0044830"(modulation by host of viral RNA genome replication)|go:"GO:0045471"(response to ethanol)|go:"GO:0045745"(positive regulation of G protein-coupled receptor signaling pathway)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045917"(positive regulation of complement activation)|go:"GO:0046718"(viral entry into host cell)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0048661"(positive regulation of smooth muscle cell proliferation)|go:"GO:0050821"(protein stabilization)|go:"GO:0050847"(progesterone receptor signaling pathway)|go:"GO:0051897"(positive regulation of protein kinase B signaling)|go:"GO:0060766"(negative regulation of androgen receptor signaling pathway)|go:"GO:0070373"(negative regulation of ERK1 and ERK2 cascade)|go:"GO:0070374"(positive regulation of ERK1 and ERK2 cascade)|go:"GO:0071354"(cellular response to interleukin-6)|go:"GO:0071897"(DNA biosynthetic process)|go:"GO:0072538"(T-helper 17 type immune response)|go:"GO:0098891"(extrinsic component of presynaptic active zone membrane)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0042826"(histone deacetylase binding)|ensembl:ENSRNOG00000046799(gene)|ensembl:ENSRNOT00000075733(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0001541"(ovarian follicle development)|go:"GO:0001552"(ovarian follicle atresia)|go:"GO:0001850"(complement component C3a binding)|go:"GO:0001851"(complement component C3b binding)|go:"GO:0002639"(positive regulation of immunoglobulin production)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0140374"(antiviral innate immune response)|go:"GO:1901224"(positive regulation of NIK/NF-kappaB signaling)|go:"GO:1990051"(activation of protein kinase C activity)|go:"GO:2000323"(negative regulation of glucocorticoid receptor signaling pathway)|interpro:IPR000163(Prohibitin)|interpro:IPR001107(Band 7 protein)|go:"GO:0098982"(GABA-ergic synapse)|interpro:IPR036013|mint:P67779|reactome:R-RNO-5673000|reactome:R-RNO-8949664|rgd:3322|refseq:NP_114039.1	-	-	-	figure legend:st1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10116(rat-hippocampus)|taxid:10116(Rattus norvegicus hippocampal neurons)	-	2020/10/30	2020/10/30	rogid:DtE+ZXAZKdCMvUW5K+jXQ5bH07M10116	rogid:eUStcZ9Mu7+7MHr/GJXFwwJY/Fc10116	rigid:zzsc1zNhBb5nwIRPeFpYOKgC3M8	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q5XIE8	uniprotkb:P19527	intact:EBI-15348306|ensembl:ENSRNOP00000023037	intact:EBI-446360|uniprotkb:Q63367|ensembl:ENSRNOP00000018599	psi-mi:itm2b_rat(display_long)|uniprotkb:Itm2b(gene name)|psi-mi:Itm2b(display_short)|uniprotkb:Immature BRI2(gene name synonym)|uniprotkb:Transmembrane protein BRI(gene name synonym)	psi-mi:nfl_rat(display_long)|uniprotkb:Neurofilament triplet L protein(gene name synonym)|uniprotkb:68 kDa neurofilament protein(gene name synonym)|uniprotkb:Nefl(gene name)|psi-mi:Nefl(display_short)|uniprotkb:Nf68(gene name synonym)|uniprotkb:Nfl(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Martins et al. (2018)	imex:IM-28469|pubmed:29476059	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26440627|imex:IM-28469-5	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSRNOG00000016271(gene)|ensembl:ENSRNOT00000023037(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001540"(amyloid-beta binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0010008"(endosome membrane)|go:"GO:0030660"(Golgi-associated vesicle membrane)|go:"GO:0031301"(integral component of organelle membrane)|go:"GO:0042985"(negative regulation of amyloid precursor protein biosynthetic process)|interpro:IPR007084(BRICHOS)|interpro:IPR040145|mint:Q5XIE8|refseq:NP_001006964.1|rgd:620727	rgd:621458|refseq:NP_113971.1|dip:DIP-1N|ensembl:ENSRNOG00000013658(gene)|ensembl:ENSRNOT00000018599(transcript)|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0005200"(structural constituent of cytoskeleton)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005882"(intermediate filament)|go:"GO:0005883"(neurofilament)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008089"(anterograde axonal transport)|go:"GO:0008090"(retrograde axonal transport)|go:"GO:0009636"(response to toxic substance)|go:"GO:0010033"(response to organic substance)|go:"GO:0014012"(peripheral nervous system axon regeneration)|go:"GO:0019896"(axonal transport of mitochondrion)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0021510"(spinal cord development)|go:"GO:0021766"(hippocampus development)|go:"GO:0021987"(cerebral cortex development)|go:"GO:0030424"(axon)|go:"GO:0030426"(growth cone)|go:"GO:0030674"(protein-macromolecule adaptor activity)|go:"GO:0031133"(regulation of axon diameter)|go:"GO:0031594"(neuromuscular junction)|go:"GO:0033693"(neurofilament bundle assembly)|go:"GO:0040011"(locomotion)|go:"GO:0042802"(identical protein binding)|go:"GO:0043005"(neuron projection)|go:"GO:0043274"(phospholipase binding)|go:"GO:0043434"(response to peptide hormone)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045105"(intermediate filament polymerization or depolymerization)|go:"GO:0045109"(intermediate filament organization)|go:"GO:0045110"(intermediate filament bundle assembly)|go:"GO:0048812"(neuron projection morphogenesis)|go:"GO:0050772"(positive regulation of axonogenesis)|go:"GO:0050885"(neuromuscular process controlling balance)|go:"GO:0051258"(protein polymerization)|go:"GO:0051412"(response to corticosterone)|go:"GO:0060052"(neurofilament cytoskeleton organization)|go:"GO:0060074"(synapse maturation)|go:"GO:0098685"(Schaffer collateral - CA1 synapse)|go:"GO:0098981"(cholinergic synapse)|go:"GO:0099182"(presynaptic intermediate filament cytoskeleton)|go:"GO:0099184"(structural constituent of postsynaptic intermediate filament cytoskeleton)|go:"GO:1903935"(response to sodium arsenite)|go:"GO:1903937"(response to acrylamide)|go:"GO:0099160"(postsynaptic intermediate filament cytoskeleton)|go:"GO:1904115"(axon cytoplasm)|interpro:IPR006821(Intermediate filament, DNA-binding region)|interpro:IPR018039|interpro:IPR027692|interpro:IPR039008|mint:P19527|reactome:R-RNO-438066|reactome:R-RNO-5673001	-	-	-	figure legend:st1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10116(rat-hippocampus)|taxid:10116(Rattus norvegicus hippocampal neurons)	-	2020/10/30	2020/10/30	rogid:DtE+ZXAZKdCMvUW5K+jXQ5bH07M10116	rogid:j/u8VG9hdvpMSY4/bU7l4hxX41Q10116	rigid:zzsc1zNhBb5nwIRPeFpYOKgC3M8	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q5XIE8	uniprotkb:P16884	intact:EBI-15348306|ensembl:ENSRNOP00000023037	intact:EBI-446344|uniprotkb:O35482|uniprotkb:Q540Z7|uniprotkb:Q63368	psi-mi:itm2b_rat(display_long)|uniprotkb:Itm2b(gene name)|psi-mi:Itm2b(display_short)|uniprotkb:Immature BRI2(gene name synonym)|uniprotkb:Transmembrane protein BRI(gene name synonym)	psi-mi:nfh_rat(display_long)|uniprotkb:Neurofilament triplet H protein(gene name synonym)|uniprotkb:200 kDa neurofilament protein(gene name synonym)|uniprotkb:Nefh(gene name)|psi-mi:Nefh(display_short)|uniprotkb:Nfh(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Martins et al. (2018)	imex:IM-28469|pubmed:29476059	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26440627|imex:IM-28469-5	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSRNOG00000016271(gene)|ensembl:ENSRNOT00000023037(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001540"(amyloid-beta binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0010008"(endosome membrane)|go:"GO:0030660"(Golgi-associated vesicle membrane)|go:"GO:0031301"(integral component of organelle membrane)|go:"GO:0042985"(negative regulation of amyloid precursor protein biosynthetic process)|interpro:IPR007084(BRICHOS)|interpro:IPR040145|mint:Q5XIE8|refseq:NP_001006964.1|rgd:620727	rgd:3159|dip:DIP-105N|mint:P16884|go:"GO:0007420"(brain development)|go:"GO:0014069"(postsynaptic density)|go:"GO:0015643"(toxic substance binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0021510"(spinal cord development)|go:"GO:0021766"(hippocampus development)|go:"GO:0021987"(cerebral cortex development)|go:"GO:0030424"(axon)|go:"GO:0030674"(protein-macromolecule adaptor activity)|go:"GO:0031103"(axon regeneration)|go:"GO:0031175"(neuron projection development)|go:"GO:0033693"(neurofilament bundle assembly)|go:"GO:0034599"(cellular response to oxidative stress)|go:"GO:0042220"(response to cocaine)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043204"(perikaryon)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045104"(intermediate filament cytoskeleton organization)|go:"GO:0045110"(intermediate filament bundle assembly)|go:"GO:0048936"(peripheral nervous system neuron axonogenesis)|go:"GO:0060052"(neurofilament cytoskeleton organization)|go:"GO:0061564"(axon development)|go:"GO:0071392"(cellular response to estradiol stimulus)|go:"GO:0071447"(cellular response to hydroperoxide)|go:"GO:0097418"(neurofibrillary tangle)|go:"GO:0097440"(apical dendrite)|go:"GO:0098685"(Schaffer collateral - CA1 synapse)|go:"GO:0099160"(postsynaptic intermediate filament cytoskeleton)|go:"GO:0099184"(structural constituent of postsynaptic intermediate filament cytoskeleton)|go:"GO:0150017"(basal proximal dendrite)|go:"GO:1902513"(regulation of organelle transport along microtubule)|go:"GO:1903935"(response to sodium arsenite)|go:"GO:1903937"(response to acrylamide)|go:"GO:1990830"(cellular response to leukemia inhibitory factor)|interpro:IPR010790(Protein of unknown function DUF1388)|interpro:IPR018039|interpro:IPR033183|interpro:IPR039008|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0001552"(ovarian follicle atresia)|go:"GO:0005200"(structural constituent of cytoskeleton)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005882"(intermediate filament)|go:"GO:0005883"(neurofilament)	-	-	-	figure legend:st1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10116(rat-hippocampus)|taxid:10116(Rattus norvegicus hippocampal neurons)	-	2020/10/30	2020/10/30	rogid:DtE+ZXAZKdCMvUW5K+jXQ5bH07M10116	rogid:ouBvM47wkf3tA9ZWmjX5jObpZtE10116	rigid:zzsc1zNhBb5nwIRPeFpYOKgC3M8	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q5XIE8	uniprotkb:P97685	intact:EBI-15348306|ensembl:ENSRNOP00000023037	intact:EBI-26437804|ensembl:ENSRNOP00000057594|uniprotkb:P97684|uniprotkb:Q91Z60	psi-mi:itm2b_rat(display_long)|uniprotkb:Itm2b(gene name)|psi-mi:Itm2b(display_short)|uniprotkb:Immature BRI2(gene name synonym)|uniprotkb:Transmembrane protein BRI(gene name synonym)	psi-mi:nfasc_rat(display_long)|uniprotkb:Nfasc(gene name)|psi-mi:Nfasc(display_short)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Martins et al. (2018)	imex:IM-28469|pubmed:29476059	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26440627|imex:IM-28469-5	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSRNOG00000016271(gene)|ensembl:ENSRNOT00000023037(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001540"(amyloid-beta binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0010008"(endosome membrane)|go:"GO:0030660"(Golgi-associated vesicle membrane)|go:"GO:0031301"(integral component of organelle membrane)|go:"GO:0042985"(negative regulation of amyloid precursor protein biosynthetic process)|interpro:IPR007084(BRICHOS)|interpro:IPR040145|mint:Q5XIE8|refseq:NP_001006964.1|rgd:620727	go:"GO:0019904"(protein domain specific binding)|ensembl:ENSRNOG00000030515(gene)|go:"GO:0030424"(axon)|ensembl:ENSRNOT00000060871(transcript)|go:"GO:0002175"(protein localization to paranode region of axon)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0005918"(septate junction)|go:"GO:0007411"(axon guidance)|go:"GO:0007422"(peripheral nervous system development)|go:"GO:0019226"(transmission of nerve impulse)|go:"GO:0030425"(dendrite)|go:"GO:0030913"(paranodal junction assembly)|go:"GO:0033010"(paranodal junction)|go:"GO:0033268"(node of Ranvier)|go:"GO:0033270"(paranode region of axon)|go:"GO:0042552"(myelination)|go:"GO:0043194"(axon initial segment)|go:"GO:0045162"(clustering of voltage-gated sodium channels)|go:"GO:0050808"(synapse organization)|go:"GO:0071205"(protein localization to juxtaparanode region of axon)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0086080"(protein binding involved in heterotypic cell-cell adhesion)|go:"GO:0097454"(Schwann cell microvillus)|interpro:IPR003598(Immunoglobulin subtype 2)|interpro:IPR003599(Immunoglobulin subtype)|interpro:IPR003961(Fibronectin, type III)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR013098(Immunoglobulin I-set)|interpro:IPR013151(Immunoglobulin)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR026965|interpro:IPR026966|interpro:IPR036116|interpro:IPR036179|interpro:IPR043204|mint:P97685|reactome:R-RNO-447043|reactome:R-RNO-6798695|refseq:NP_001153785.1|refseq:NP_001153786.1|refseq:NP_446361.1|rgd:620911	-	-	-	figure legend:st1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10116(rat-hippocampus)|taxid:10116(Rattus norvegicus hippocampal neurons)	-	2020/10/30	2020/10/30	rogid:DtE+ZXAZKdCMvUW5K+jXQ5bH07M10116	rogid:HzCYcx8+shkIPZAc7h3T3dYDxDc10116	rigid:zzsc1zNhBb5nwIRPeFpYOKgC3M8	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q5XIE8	uniprotkb:P55067	intact:EBI-15348306|ensembl:ENSRNOP00000023037	intact:EBI-26437766	psi-mi:itm2b_rat(display_long)|uniprotkb:Itm2b(gene name)|psi-mi:Itm2b(display_short)|uniprotkb:Immature BRI2(gene name synonym)|uniprotkb:Transmembrane protein BRI(gene name synonym)	psi-mi:ncan_rat(display_long)|uniprotkb:Ncan(gene name)|psi-mi:Ncan(display_short)|uniprotkb:Cspg3(gene name synonym)|uniprotkb:245 kDa early postnatal core glycoprotein(gene name synonym)|uniprotkb:Chondroitin sulfate proteoglycan 3(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Martins et al. (2018)	imex:IM-28469|pubmed:29476059	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26440627|imex:IM-28469-5	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSRNOG00000016271(gene)|ensembl:ENSRNOT00000023037(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001540"(amyloid-beta binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0010008"(endosome membrane)|go:"GO:0030660"(Golgi-associated vesicle membrane)|go:"GO:0031301"(integral component of organelle membrane)|go:"GO:0042985"(negative regulation of amyloid precursor protein biosynthetic process)|interpro:IPR007084(BRICHOS)|interpro:IPR040145|mint:Q5XIE8|refseq:NP_001006964.1|rgd:620727	go:"GO:0001501"(skeletal system development)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005540"(hyaluronic acid binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005886"(plasma membrane)|go:"GO:0007155"(cell adhesion)|go:"GO:0007417"(central nervous system development)|go:"GO:0030246"(carbohydrate binding)|go:"GO:0031012"(extracellular matrix)|go:"GO:0045202"(synapse)|go:"GO:0051823"(regulation of synapse structural plasticity)|go:"GO:0072534"(perineuronal net)|reactome:R-RNO-1971475|reactome:R-RNO-2022870|reactome:R-RNO-2022923|reactome:R-RNO-2024101|reactome:R-RNO-3000178|mint:P55067|interpro:IPR001304(C-type lectin)|interpro:IPR016186(C-type lectin-like)|interpro:IPR018378|interpro:IPR016187(C-type lectin fold)|interpro:IPR001881(EGF-like calcium-binding)|interpro:IPR000742(EGF-like, type 3)|interpro:IPR000152(Aspartic acid and asparagine hydroxylation site)|interpro:IPR018097|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR036179|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR003599(Immunoglobulin subtype)|interpro:IPR013106(Immunoglobulin V-set)|interpro:IPR000538(Link)|interpro:IPR035976|interpro:IPR000436(Sushi/SCR/CCP)|rgd:619941	-	-	-	figure legend:st1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10116(rat-hippocampus)|taxid:10116(Rattus norvegicus hippocampal neurons)	-	2020/10/30	2020/10/30	rogid:DtE+ZXAZKdCMvUW5K+jXQ5bH07M10116	rogid:2/ICeFV747SqaUpp9GStWXPuhcc10116	rigid:zzsc1zNhBb5nwIRPeFpYOKgC3M8	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q5XIE8	uniprotkb:Q64119	intact:EBI-15348306|ensembl:ENSRNOP00000023037	intact:EBI-26437750	psi-mi:itm2b_rat(display_long)|uniprotkb:Itm2b(gene name)|psi-mi:Itm2b(display_short)|uniprotkb:Immature BRI2(gene name synonym)|uniprotkb:Transmembrane protein BRI(gene name synonym)	psi-mi:myl6_rat(display_long)|uniprotkb:Myl6(gene name)|psi-mi:Myl6(display_short)|uniprotkb:17 kDa myosin light chain(gene name synonym)|uniprotkb:Myosin light chain 3(gene name synonym)|uniprotkb:Myosin light chain alkali 3(gene name synonym)|uniprotkb:Smooth muscle and nonmuscle myosin light chain alkali 6(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Martins et al. (2018)	imex:IM-28469|pubmed:29476059	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26440627|imex:IM-28469-5	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSRNOG00000016271(gene)|ensembl:ENSRNOT00000023037(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001540"(amyloid-beta binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0010008"(endosome membrane)|go:"GO:0030660"(Golgi-associated vesicle membrane)|go:"GO:0031301"(integral component of organelle membrane)|go:"GO:0042985"(negative regulation of amyloid precursor protein biosynthetic process)|interpro:IPR007084(BRICHOS)|interpro:IPR040145|mint:Q5XIE8|refseq:NP_001006964.1|rgd:620727	go:"GO:0000146"(microfilament motor activity)|go:"GO:0003774"(cytoskeletal motor activity)|go:"GO:0005509"(calcium ion binding)|go:"GO:0006936"(muscle contraction)|go:"GO:0007519"(skeletal muscle tissue development)|go:"GO:0008307"(structural constituent of muscle)|go:"GO:0016459"(myosin complex)|go:"GO:0016461"(unconventional myosin complex)|go:"GO:0030049"(muscle filament sliding)|mint:Q64119|refseq:NP_001094453.1|interpro:IPR011992(EF-Hand type)|interpro:IPR002048(Calcium-binding EF-hand)|rgd:1305620	-	-	-	figure legend:st1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10116(rat-hippocampus)|taxid:10116(Rattus norvegicus hippocampal neurons)	-	2020/10/30	2020/10/30	rogid:DtE+ZXAZKdCMvUW5K+jXQ5bH07M10116	rogid:7L1ZyEG5CDK89dn56Tvy1TZlSPc10116	rigid:zzsc1zNhBb5nwIRPeFpYOKgC3M8	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q5XIE8	uniprotkb:Q63560	intact:EBI-15348306|ensembl:ENSRNOP00000023037	intact:EBI-1638469|uniprotkb:O88748|uniprotkb:Q6AYX8	psi-mi:itm2b_rat(display_long)|uniprotkb:Itm2b(gene name)|psi-mi:Itm2b(display_short)|uniprotkb:Immature BRI2(gene name synonym)|uniprotkb:Transmembrane protein BRI(gene name synonym)	psi-mi:map6_rat(display_long)|uniprotkb:Map6(gene name)|psi-mi:Map6(display_short)|uniprotkb:Mtap6(gene name synonym)|uniprotkb:Stable tubule-only polypeptide(gene name synonym)|uniprotkb:145-kDa STOP(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Martins et al. (2018)	imex:IM-28469|pubmed:29476059	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26440627|imex:IM-28469-5	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSRNOG00000016271(gene)|ensembl:ENSRNOT00000023037(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001540"(amyloid-beta binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0010008"(endosome membrane)|go:"GO:0030660"(Golgi-associated vesicle membrane)|go:"GO:0031301"(integral component of organelle membrane)|go:"GO:0042985"(negative regulation of amyloid precursor protein biosynthetic process)|interpro:IPR007084(BRICHOS)|interpro:IPR040145|mint:Q5XIE8|refseq:NP_001006964.1|rgd:620727	interpro:IPR007882(STOP)|rgd:61804|refseq:NP_058900.1|mint:Q63560|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005798"(Golgi-associated vesicle)|go:"GO:0005801"(cis-Golgi network)|go:"GO:0005874"(microtubule)|go:"GO:0008017"(microtubule binding)|go:"GO:0019896"(axonal transport of mitochondrion)|go:"GO:0030424"(axon)|go:"GO:0030425"(dendrite)|go:"GO:0030658"(transport vesicle membrane)|go:"GO:0030705"(cytoskeleton-dependent intracellular transport)|go:"GO:0032418"(lysosome localization)|go:"GO:0043005"(neuron projection)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0048813"(dendrite morphogenesis)|go:"GO:0050772"(positive regulation of axonogenesis)|go:"GO:0070507"(regulation of microtubule cytoskeleton organization)|go:"GO:0099503"(secretory vesicle)|go:"GO:1904115"(axon cytoplasm)	-	-	-	figure legend:st1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10116(rat-hippocampus)|taxid:10116(Rattus norvegicus hippocampal neurons)	-	2020/10/30	2020/10/30	rogid:DtE+ZXAZKdCMvUW5K+jXQ5bH07M10116	rogid:lWnLN3HrXruyxTIYdSN5wtDmea010116	rigid:zzsc1zNhBb5nwIRPeFpYOKgC3M8	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q5XIE8	uniprotkb:P15205	intact:EBI-15348306|ensembl:ENSRNOP00000023037	intact:EBI-349666|uniprotkb:Q62958|uniprotkb:Q9ER21|uniprotkb:Q9QW92|ensembl:ENSRNOP00000023460|uniprotkb:B0BNK3|uniprotkb:F1LRL9	psi-mi:itm2b_rat(display_long)|uniprotkb:Itm2b(gene name)|psi-mi:Itm2b(display_short)|uniprotkb:Immature BRI2(gene name synonym)|uniprotkb:Transmembrane protein BRI(gene name synonym)	psi-mi:map1b_rat(display_long)|uniprotkb:Map1b(gene name)|psi-mi:Map1b(display_short)|uniprotkb:Neuraxin(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Martins et al. (2018)	imex:IM-28469|pubmed:29476059	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26440627|imex:IM-28469-5	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSRNOG00000016271(gene)|ensembl:ENSRNOT00000023037(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001540"(amyloid-beta binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0010008"(endosome membrane)|go:"GO:0030660"(Golgi-associated vesicle membrane)|go:"GO:0031301"(integral component of organelle membrane)|go:"GO:0042985"(negative regulation of amyloid precursor protein biosynthetic process)|interpro:IPR007084(BRICHOS)|interpro:IPR040145|mint:Q5XIE8|refseq:NP_001006964.1|rgd:620727	rgd:3043|refseq:NP_062090.1|ensembl:ENSRNOG00000017428(gene)|ensembl:ENSRNOT00000023460(transcript)|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0001578"(microtubule bundle formation)|go:"GO:0001750"(photoreceptor outer segment)|go:"GO:0003779"(actin binding)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005874"(microtubule)|go:"GO:0005875"(microtubule associated complex)|go:"GO:0005886"(plasma membrane)|go:"GO:0007026"(negative regulation of microtubule depolymerization)|go:"GO:0007399"(nervous system development)|go:"GO:0007409"(axonogenesis)|go:"GO:0007416"(synapse assembly)|go:"GO:0008017"(microtubule binding)|go:"GO:0009611"(response to wounding)|go:"GO:0009612"(response to mechanical stimulus)|go:"GO:0009743"(response to carbohydrate)|go:"GO:0009987"(cellular process)|go:"GO:0010035"(response to inorganic substance)|go:"GO:0014012"(peripheral nervous system axon regeneration)|go:"GO:0014069"(postsynaptic density)|go:"GO:0016358"(dendrite development)|go:"GO:0017085"(response to insecticide)|go:"GO:0005543"(phospholipid binding)|go:"GO:0048675"(axon extension)|go:"GO:0048678"(response to axon injury)|go:"GO:0051915"(induction of synaptic plasticity by chemical substance)|go:"GO:0061162"(establishment of monopolar cell polarity)|go:"GO:0071363"(cellular response to growth factor stimulus)|go:"GO:0071375"(cellular response to peptide hormone stimulus)|go:"GO:0097440"(apical dendrite)|go:"GO:0097441"(basal dendrite)|go:"GO:0097457"(hippocampal mossy fiber)|interpro:IPR000102(Neuraxin/MAP1B repeat)|interpro:IPR026074|interpro:IPR027321|mint:P15205|go:"GO:0030424"(axon)|go:"GO:0030425"(dendrite)|go:"GO:0030426"(growth cone)|go:"GO:0031114"(regulation of microtubule depolymerization)|go:"GO:0021700"(developmental maturation)|go:"GO:0031116"(positive regulation of microtubule polymerization)|go:"GO:0031667"(response to nutrient levels)|go:"GO:0032355"(response to estradiol)|go:"GO:0032387"(negative regulation of intracellular transport)|go:"GO:0033189"(response to vitamin A)|go:"GO:0036477"(somatodendritic compartment)|go:"GO:0042493"|go:"GO:0043025"(neuronal cell body)|go:"GO:0043196"(varicosity)|go:"GO:0043197"(dendritic spine)|go:"GO:0043204"(perikaryon)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045202"(synapse)|go:"GO:0045666"(positive regulation of neuron differentiation)|go:"GO:0045773"(positive regulation of axon extension)|go:"GO:0047497"(mitochondrion transport along microtubule)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0048666"(neuron development)	-	-	-	figure legend:st1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10116(rat-hippocampus)|taxid:10116(Rattus norvegicus hippocampal neurons)	-	2020/10/30	2020/10/30	rogid:DtE+ZXAZKdCMvUW5K+jXQ5bH07M10116	rogid:ymryqrEfxWtJQiPb6jgYe8bzDX410116	rigid:zzsc1zNhBb5nwIRPeFpYOKgC3M8	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q5XIE8	uniprotkb:Q3KR86	intact:EBI-15348306|ensembl:ENSRNOP00000023037	intact:EBI-16220282	psi-mi:itm2b_rat(display_long)|uniprotkb:Itm2b(gene name)|psi-mi:Itm2b(display_short)|uniprotkb:Immature BRI2(gene name synonym)|uniprotkb:Transmembrane protein BRI(gene name synonym)	psi-mi:mic60_rat(display_long)|uniprotkb:Immt(gene name)|psi-mi:Immt(display_short)|uniprotkb:Mic60(gene name synonym)|uniprotkb:Mitochondrial inner membrane protein(gene name synonym)|uniprotkb:Mitofilin(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Martins et al. (2018)	imex:IM-28469|pubmed:29476059	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26440627|imex:IM-28469-5	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSRNOG00000016271(gene)|ensembl:ENSRNOT00000023037(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001540"(amyloid-beta binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0010008"(endosome membrane)|go:"GO:0030660"(Golgi-associated vesicle membrane)|go:"GO:0031301"(integral component of organelle membrane)|go:"GO:0042985"(negative regulation of amyloid precursor protein biosynthetic process)|interpro:IPR007084(BRICHOS)|interpro:IPR040145|mint:Q5XIE8|refseq:NP_001006964.1|rgd:620727	go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005758"(mitochondrial intermembrane space)|go:"GO:0009409"(response to cold)|go:"GO:0042407"(cristae formation)|go:"GO:0051560"(mitochondrial calcium ion homeostasis)|go:"GO:0061617"(MICOS complex)|mint:Q3KR86|rgd:1310684|refseq:NP_001030100.1|interpro:IPR019133	-	-	-	figure legend:st1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10116(rat-hippocampus)|taxid:10116(Rattus norvegicus hippocampal neurons)	-	2020/10/30	2020/10/30	rogid:DtE+ZXAZKdCMvUW5K+jXQ5bH07M10116	rogid:8w7k7GqkoWnY0fLU70i0ItueVVI10116	rigid:zzsc1zNhBb5nwIRPeFpYOKgC3M8	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q5XIE8	uniprotkb:Q2PQA9	intact:EBI-15348306|ensembl:ENSRNOP00000023037	intact:EBI-920191|uniprotkb:Q9WV65|ensembl:ENSRNOP00000023860	psi-mi:itm2b_rat(display_long)|uniprotkb:Itm2b(gene name)|psi-mi:Itm2b(display_short)|uniprotkb:Immature BRI2(gene name synonym)|uniprotkb:Transmembrane protein BRI(gene name synonym)	psi-mi:kinh_rat(display_long)|uniprotkb:Kif5b(gene name)|psi-mi:Kif5b(display_short)|uniprotkb:Ubiquitous kinesin heavy chain(gene name synonym)|uniprotkb:Conventional kinesin heavy chain(gene name synonym)|uniprotkb:Khc(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Martins et al. (2018)	imex:IM-28469|pubmed:29476059	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26440627|imex:IM-28469-5	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSRNOG00000016271(gene)|ensembl:ENSRNOT00000023037(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001540"(amyloid-beta binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0010008"(endosome membrane)|go:"GO:0030660"(Golgi-associated vesicle membrane)|go:"GO:0031301"(integral component of organelle membrane)|go:"GO:0042985"(negative regulation of amyloid precursor protein biosynthetic process)|interpro:IPR007084(BRICHOS)|interpro:IPR040145|mint:Q5XIE8|refseq:NP_001006964.1|rgd:620727	rgd:621559|refseq:NP_476550.1|refseq:XP_006254067.1|ensembl:ENSRNOG00000017466(gene)|ensembl:ENSRNOT00000023861(transcript)|go:"GO:0003777"(microtubule motor activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005829"(cytosol)|go:"GO:0005871"(kinesin complex)|go:"GO:0005874"(microtubule)|go:"GO:0007018"(microtubule-based movement)|go:"GO:0007028"(cytoplasm organization)|go:"GO:0007411"(axon guidance)|go:"GO:0007420"(brain development)|go:"GO:0008017"(microtubule binding)|go:"GO:0008432"(JUN kinase binding)|go:"GO:0008574"(plus-end-directed microtubule motor activity)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0021766"(hippocampus development)|go:"GO:0030139"(endocytic vesicle)|go:"GO:0030705"(cytoskeleton-dependent intracellular transport)|go:"GO:0031340"(positive regulation of vesicle fusion)|go:"GO:0031982"(vesicle)|go:"GO:0032230"(positive regulation of synaptic transmission, GABAergic)|go:"GO:0032418"(lysosome localization)|go:"GO:0032839"(dendrite cytoplasm)|go:"GO:0034451"(centriolar satellite)|go:"GO:0035253"(ciliary rootlet)|go:"GO:0035617"(stress granule disassembly)|go:"GO:0035774"(positive regulation of insulin secretion involved in cellular response to glucose stimulus)|go:"GO:0042267"(natural killer cell mediated cytotoxicity)|go:"GO:0042391"(regulation of membrane potential)|go:"GO:0042802"(identical protein binding)|go:"GO:0043005"(neuron projection)|go:"GO:0043227"(membrane-bounded organelle)|go:"GO:0043268"(positive regulation of potassium ion transport)|go:"GO:0044295"(axonal growth cone)|go:"GO:0045335"(phagocytic vesicle)|go:"GO:0047496"(vesicle transport along microtubule)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0048489"(synaptic vesicle transport)|go:"GO:0051642"(centrosome localization)|go:"GO:0071346"(cellular response to interferon-gamma)|go:"GO:0072383"(plus-end-directed vesicle transport along microtubule)|go:"GO:0090316"(positive regulation of intracellular protein transport)|go:"GO:0098971"(anterograde dendritic transport of neurotransmitter receptor complex)|go:"GO:0099609"(microtubule lateral binding)|go:"GO:0099641"(anterograde axonal protein transport)|go:"GO:1903078"(positive regulation of protein localization to plasma membrane)|go:"GO:1904115"(axon cytoplasm)|go:"GO:1905152"(positive regulation of voltage-gated sodium channel activity)|go:"GO:1990049"(retrograde neuronal dense core vesicle transport)|interpro:IPR001752(Kinesin, motor region)|interpro:IPR019821|interpro:IPR027417|interpro:IPR027640|interpro:IPR036961|mint:Q2PQA9|rcsb pdb:4ATX|reactome:R-RNO-2132295|reactome:R-RNO-5625970|reactome:R-RNO-6811434|reactome:R-RNO-983189|dip:DIP-37054N	-	-	-	figure legend:st1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10116(rat-hippocampus)|taxid:10116(Rattus norvegicus hippocampal neurons)	-	2020/10/30	2020/10/30	rogid:DtE+ZXAZKdCMvUW5K+jXQ5bH07M10116	rogid:OjHE/OLj2diwiW5HI0HFHEDkbjY10116	rigid:zzsc1zNhBb5nwIRPeFpYOKgC3M8	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q5XIE8	uniprotkb:P37285	intact:EBI-15348306|ensembl:ENSRNOP00000023037	intact:EBI-917396|ensembl:ENSRNOP00000075931	psi-mi:itm2b_rat(display_long)|uniprotkb:Itm2b(gene name)|psi-mi:Itm2b(display_short)|uniprotkb:Immature BRI2(gene name synonym)|uniprotkb:Transmembrane protein BRI(gene name synonym)	psi-mi:klc1_rat(display_long)|uniprotkb:Klc1(gene name)|psi-mi:Klc1(display_short)|uniprotkb:Klc(gene name synonym)|uniprotkb:Kns2(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Martins et al. (2018)	imex:IM-28469|pubmed:29476059	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26440627|imex:IM-28469-5	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSRNOG00000016271(gene)|ensembl:ENSRNOT00000023037(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001540"(amyloid-beta binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0010008"(endosome membrane)|go:"GO:0030660"(Golgi-associated vesicle membrane)|go:"GO:0031301"(integral component of organelle membrane)|go:"GO:0042985"(negative regulation of amyloid precursor protein biosynthetic process)|interpro:IPR007084(BRICHOS)|interpro:IPR040145|mint:Q5XIE8|refseq:NP_001006964.1|rgd:620727	rgd:621411|refseq:NP_001075442.1|refseq:NP_001075443.1|dip:DIP-36927N|ensembl:ENSRNOG00000011572(gene)|ensembl:ENSRNOT00000092774(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005871"(kinesin complex)|go:"GO:0005874"(microtubule)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0008088"(axo-dendritic transport)|go:"GO:0015631"(tubulin binding)|go:"GO:0016020"(membrane)|go:"GO:0030424"(axon)|go:"GO:0030426"(growth cone)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0031982"(vesicle)|go:"GO:0035253"(ciliary rootlet)|go:"GO:0035418"(protein localization to synapse)|go:"GO:0035617"(stress granule disassembly)|go:"GO:0043005"(neuron projection)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043227"(membrane-bounded organelle)|interpro:IPR002151(Kinesin light chain)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR015792(Kinesin light chain repeat)|interpro:IPR019734|mint:P37285|reactome:R-RNO-2132295|reactome:R-RNO-5625970|reactome:R-RNO-6811434|reactome:R-RNO-983189	-	-	-	figure legend:st1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10116(rat-hippocampus)|taxid:10116(Rattus norvegicus hippocampal neurons)	-	2020/10/30	2020/10/30	rogid:DtE+ZXAZKdCMvUW5K+jXQ5bH07M10116	rogid:4o3poOHtmPnoLq/XTguA0Z1P14o10116	rigid:zzsc1zNhBb5nwIRPeFpYOKgC3M8	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q5XIE8	uniprotkb:Q63617	intact:EBI-15348306|ensembl:ENSRNOP00000023037	intact:EBI-8761989	psi-mi:itm2b_rat(display_long)|uniprotkb:Itm2b(gene name)|psi-mi:Itm2b(display_short)|uniprotkb:Immature BRI2(gene name synonym)|uniprotkb:Transmembrane protein BRI(gene name synonym)	psi-mi:hyou1_rat(display_long)|uniprotkb:Hyou1(gene name)|psi-mi:Hyou1(display_short)|uniprotkb:Orp150(gene name synonym)|uniprotkb:150 kDa oxygen-regulated protein(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Martins et al. (2018)	imex:IM-28469|pubmed:29476059	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26440627|imex:IM-28469-5	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSRNOG00000016271(gene)|ensembl:ENSRNOT00000023037(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001540"(amyloid-beta binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0010008"(endosome membrane)|go:"GO:0030660"(Golgi-associated vesicle membrane)|go:"GO:0031301"(integral component of organelle membrane)|go:"GO:0042985"(negative regulation of amyloid precursor protein biosynthetic process)|interpro:IPR007084(BRICHOS)|interpro:IPR040145|mint:Q5XIE8|refseq:NP_001006964.1|rgd:620727	mint:Q63617|interpro:IPR018181|interpro:IPR013126(Heat shock protein 70)|refseq:NP_620222.2|rgd:621146|interpro:IPR029047|interpro:IPR029048|go:"GO:0001666"(response to hypoxia)|go:"GO:0002931"(response to ischemia)|go:"GO:0005524"(ATP binding)|go:"GO:0005788"(endoplasmic reticulum lumen)|go:"GO:0005790"(smooth endoplasmic reticulum)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0034663"(endoplasmic reticulum chaperone complex)|go:"GO:0034976"(response to endoplasmic reticulum stress)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0071456"(cellular response to hypoxia)|go:"GO:1903298"(negative regulation of hypoxia-induced intrinsic apoptotic signaling pathway)|go:"GO:1903382"(negative regulation of endoplasmic reticulum stress-induced neuron intrinsic apoptotic signaling pathway)|interpro:IPR043129	-	-	-	figure legend:st1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10116(rat-hippocampus)|taxid:10116(Rattus norvegicus hippocampal neurons)	-	2020/10/30	2020/10/30	rogid:DtE+ZXAZKdCMvUW5K+jXQ5bH07M10116	rogid:a64+yExj4exM2hN2NiQHoMi/Y4A10116	rigid:zzsc1zNhBb5nwIRPeFpYOKgC3M8	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q5XIE8	uniprotkb:P62804	intact:EBI-15348306|ensembl:ENSRNOP00000023037	intact:EBI-16220020|ensembl:ENSRNOP00000039602|ensembl:ENSRNOP00000066622|ensembl:ENSRNOP00000066653|ensembl:ENSRNOP00000066695|ensembl:ENSRNOP00000067176|ensembl:ENSRNOP00000067502|ensembl:ENSRNOP00000067813|ensembl:ENSRNOP00000069989|ensembl:ENSRNOP00000071163|ensembl:ENSRNOP00000074659|ensembl:ENSRNOP00000074796|ensembl:ENSRNOP00000065233|uniprotkb:P02304|uniprotkb:P02305|uniprotkb:Q5BM23|uniprotkb:Q7M0E8	psi-mi:itm2b_rat(display_long)|uniprotkb:Itm2b(gene name)|psi-mi:Itm2b(display_short)|uniprotkb:Immature BRI2(gene name synonym)|uniprotkb:Transmembrane protein BRI(gene name synonym)	psi-mi:h4_rat(display_long)|uniprotkb:H4c2(gene name)|psi-mi:H4c2(display_short)|uniprotkb:H4f16(gene name)|psi-mi:H4f16(display_short)|uniprotkb:Hist4h4(gene name synonym)|uniprotkb:Hist1h4b(gene name synonym)|uniprotkb:Hist4(gene name synonym)|uniprotkb:Hist1h4m(gene name)|psi-mi:Hist1h4m(display_short)|uniprotkb:H4ft(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Martins et al. (2018)	imex:IM-28469|pubmed:29476059	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26440627|imex:IM-28469-5	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSRNOG00000016271(gene)|ensembl:ENSRNOT00000023037(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001540"(amyloid-beta binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0010008"(endosome membrane)|go:"GO:0030660"(Golgi-associated vesicle membrane)|go:"GO:0031301"(integral component of organelle membrane)|go:"GO:0042985"(negative regulation of amyloid precursor protein biosynthetic process)|interpro:IPR007084(BRICHOS)|interpro:IPR040145|mint:Q5XIE8|refseq:NP_001006964.1|rgd:620727	ensembl:ENSRNOG00000032224(gene)|ensembl:ENSRNOG00000045840(gene)|ensembl:ENSRNOG00000045978(gene)|ensembl:ENSRNOG00000046636(gene)|ensembl:ENSRNOG00000048215(gene)|ensembl:ENSRNOG00000048642(gene)|ensembl:ENSRNOG00000048735(gene)|ensembl:ENSRNOG00000050933(gene)|ensembl:ENSRNOG00000051891(gene)|ensembl:ENSRNOG00000054017(gene)|ensembl:ENSRNOG00000057690(gene)|ensembl:ENSRNOG00000058444(gene)|ensembl:ENSRNOT00000040210(transcript)|ensembl:ENSRNOT00000071512(transcript)|ensembl:ENSRNOT00000072147(transcript)|ensembl:ENSRNOT00000072286(transcript)|ensembl:ENSRNOT00000074109(transcript)|ensembl:ENSRNOT00000074198(transcript)|ensembl:ENSRNOT00000074526(transcript)|ensembl:ENSRNOT00000075065(transcript)|ensembl:ENSRNOT00000080490(transcript)|ensembl:ENSRNOT00000085381(transcript)|ensembl:ENSRNOT00000088408(transcript)|ensembl:ENSRNOT00000091201(transcript)|go:"GO:0000228"(nuclear chromosome)|go:"GO:0000786"(nucleosome)|go:"GO:0001503"(ossification)|go:"GO:0003677"(DNA binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006334"(nucleosome assembly)|go:"GO:0006335"(DNA replication-dependent chromatin assembly)|go:"GO:0006336"(DNA replication-independent chromatin assembly)|go:"GO:0006352"(DNA-templated transcription, initiation)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030154"(cell differentiation)|go:"GO:0032991"(protein-containing complex)|go:"GO:0045653"(negative regulation of megakaryocyte differentiation)|go:"GO:0046982"(protein heterodimerization activity)|interpro:IPR001951(Histone H4)|interpro:IPR004823("TATA box binding protein associated factor (TAF)")|interpro:IPR009072(Histone-fold)|interpro:IPR019809|interpro:IPR035425|mint:P62804|reactome:R-RNO-110330|reactome:R-RNO-110331|reactome:R-RNO-171306|reactome:R-RNO-201722|reactome:R-RNO-212300|reactome:R-RNO-2299718|reactome:R-RNO-2559580|reactome:R-RNO-2559582|reactome:R-RNO-2559586|reactome:R-RNO-3214841|reactome:R-RNO-3214842|reactome:R-RNO-3214847|reactome:R-RNO-3214858|reactome:R-RNO-427359|reactome:R-RNO-427413|reactome:R-RNO-4551638|reactome:R-RNO-5250924|reactome:R-RNO-5578749|reactome:R-RNO-5625886|reactome:R-RNO-5693565|reactome:R-RNO-5693571|reactome:R-RNO-5693607|reactome:R-RNO-606279|reactome:R-RNO-69473|reactome:R-RNO-73728|reactome:R-RNO-73772|reactome:R-RNO-8936459|reactome:R-RNO-9018519|reactome:R-RNO-9670095|rgd:620814|refseq:NP_001116941.1|refseq:NP_001258150.1|refseq:NP_073177.1|refseq:XP_003749904.3|refseq:XP_008761668.1|refseq:XP_008761670.1|refseq:XP_008769992.1|refseq:XP_008772221.1|refseq:XP_578415.4	-	-	-	figure legend:st1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10116(rat-hippocampus)|taxid:10116(Rattus norvegicus hippocampal neurons)	-	2020/10/30	2020/10/30	rogid:DtE+ZXAZKdCMvUW5K+jXQ5bH07M10116	rogid:LZSfhrpw0PcDREEoJ1UMkBvnUfA10116	rigid:zzsc1zNhBb5nwIRPeFpYOKgC3M8	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q5XIE8	uniprotkb:Q00715	intact:EBI-15348306|ensembl:ENSRNOP00000023037	intact:EBI-931728	psi-mi:itm2b_rat(display_long)|uniprotkb:Itm2b(gene name)|psi-mi:Itm2b(display_short)|uniprotkb:Immature BRI2(gene name synonym)|uniprotkb:Transmembrane protein BRI(gene name synonym)	psi-mi:h2b1_rat(display_long)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Martins et al. (2018)	imex:IM-28469|pubmed:29476059	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26440627|imex:IM-28469-5	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSRNOG00000016271(gene)|ensembl:ENSRNOT00000023037(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001540"(amyloid-beta binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0010008"(endosome membrane)|go:"GO:0030660"(Golgi-associated vesicle membrane)|go:"GO:0031301"(integral component of organelle membrane)|go:"GO:0042985"(negative regulation of amyloid precursor protein biosynthetic process)|interpro:IPR007084(BRICHOS)|interpro:IPR040145|mint:Q5XIE8|refseq:NP_001006964.1|rgd:620727	refseq:NP_072173.1|interpro:IPR009072(Histone-fold)|interpro:IPR007125(Histone core)|interpro:IPR000558(Histone H2B)|mint:Q00715|go:"GO:0000786"(nucleosome)|go:"GO:0003677"(DNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006334"(nucleosome assembly)|go:"GO:0042742"(defense response to bacterium)|go:"GO:0046982"(protein heterodimerization activity)	-	-	-	figure legend:st1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10116(rat-hippocampus)|taxid:10116(Rattus norvegicus hippocampal neurons)	-	2020/10/30	2020/10/30	rogid:DtE+ZXAZKdCMvUW5K+jXQ5bH07M10116	rogid:MmU330IlxzGgIpswI5joy179agY10116	rigid:zzsc1zNhBb5nwIRPeFpYOKgC3M8	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q5XIE8	uniprotkb:P34058	intact:EBI-15348306|ensembl:ENSRNOP00000023037	intact:EBI-917279|uniprotkb:Q1PSW2|uniprotkb:Q66H55|uniprotkb:Q68GV5|uniprotkb:Q9QWC6|ensembl:ENSRNOP00000026920	psi-mi:itm2b_rat(display_long)|uniprotkb:Itm2b(gene name)|psi-mi:Itm2b(display_short)|uniprotkb:Immature BRI2(gene name synonym)|uniprotkb:Transmembrane protein BRI(gene name synonym)	psi-mi:hs90b_rat(display_long)|uniprotkb:Heat shock 84 kDa(gene name synonym)|uniprotkb:Hsp90ab1(gene name)|psi-mi:Hsp90ab1(display_short)|uniprotkb:Hsp84(gene name synonym)|uniprotkb:Hspcb(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Martins et al. (2018)	imex:IM-28469|pubmed:29476059	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26440627|imex:IM-28469-5	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSRNOG00000016271(gene)|ensembl:ENSRNOT00000023037(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001540"(amyloid-beta binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0010008"(endosome membrane)|go:"GO:0030660"(Golgi-associated vesicle membrane)|go:"GO:0031301"(integral component of organelle membrane)|go:"GO:0042985"(negative regulation of amyloid precursor protein biosynthetic process)|interpro:IPR007084(BRICHOS)|interpro:IPR040145|mint:Q5XIE8|refseq:NP_001006964.1|rgd:620727	rgd:1303075|refseq:NP_001004082.3|ensembl:ENSRNOG00000019834(gene)|ensembl:ENSRNOT00000026920(transcript)|go:"GO:0001890"(placenta development)|go:"GO:0002134"(UTP binding)|go:"GO:0002135"(CTP binding)|go:"GO:0003725"(double-stranded RNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005525"(GTP binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006457"(protein folding)|go:"GO:0006986"(response to unfolded protein)|go:"GO:0007004"(telomere maintenance via telomerase)|go:"GO:0008180"(COP9 signalosome)|go:"GO:0009651"(response to salt stress)|go:"GO:0009986"(cell surface)|go:"GO:0010033"(response to organic substance)|go:"GO:0016234"(inclusion body)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0017098"(sulfonylurea receptor binding)|go:"GO:0019062"(virion attachment to host cell)|go:"GO:0019887"(protein kinase regulator activity)|go:"GO:0019900"(kinase binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0021955"(central nervous system neuron axonogenesis)|go:"GO:0030010"(establishment of cell polarity)|go:"GO:0030511"(positive regulation of transforming growth factor beta receptor signaling pathway)|go:"GO:0031072"(heat shock protein binding)|go:"GO:0031396"(regulation of protein ubiquitination)|go:"GO:0031526"(brush border membrane)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032092"(positive regulation of protein binding)|go:"GO:0032435"(negative regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0032516"(positive regulation of phosphoprotein phosphatase activity)|go:"GO:0032564"(dATP binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033138"(positive regulation of peptidyl-serine phosphorylation)|go:"GO:0034605"(cellular response to heat)|go:"GO:0034751"(aryl hydrocarbon receptor complex)|go:"GO:0042220"(response to cocaine)|go:"GO:0042277"(peptide binding)|go:"GO:0042307"(positive regulation of protein import into nucleus)|go:"GO:0042470"(melanosome)|go:"GO:0042493"|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0043008"(ATP-dependent protein binding)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043202"(lysosomal lumen)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0044183"(protein folding chaperone)|go:"GO:0044294"(dendritic growth cone)|go:"GO:0044295"(axonal growth cone)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0045597"(positive regulation of cell differentiation)|go:"GO:0045793"(positive regulation of cell size)|go:"GO:0046983"(protein dimerization activity)|go:"GO:0048156"(tau protein binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0048675"(axon extension)|go:"GO:0050821"(protein stabilization)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0051131"(chaperone-mediated protein complex assembly)|go:"GO:0051248"(negative regulation of protein metabolic process)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0051897"(positive regulation of protein kinase B signaling)|go:"GO:0051973"(positive regulation of telomerase activity)|go:"GO:0060334"(regulation of interferon-gamma-mediated signaling pathway)|go:"GO:0060338"(regulation of type I interferon-mediated signaling pathway)|go:"GO:0061635"(regulation of protein complex stability)|go:"GO:0061684"(chaperone-mediated autophagy)|go:"GO:0070182"(DNA polymerase binding)|go:"GO:0071353"(cellular response to interleukin-4)|go:"GO:0071407"(cellular response to organic cyclic compound)|go:"GO:0071902"(positive regulation of protein serine/threonine kinase activity)|go:"GO:0097435"(supramolecular fiber organization)|go:"GO:0097718"(disordered domain specific binding)|go:"GO:0120293"(dynein axonemal particle)|go:"GO:0140597"(protein carrier chaperone)|go:"GO:1901389"(negative regulation of transforming growth factor beta activation)|go:"GO:1901799"(negative regulation of proteasomal protein catabolic process)|go:"GO:1903660"(negative regulation of complement-dependent cytotoxicity)|go:"GO:1903827"|go:"GO:1904031"(positive regulation of cyclin-dependent protein kinase activity)|go:"GO:1905323"(telomerase holoenzyme complex assembly)|go:"GO:1990226"(histone methyltransferase binding)|go:"GO:1990565"(HSP90-CDC37 chaperone complex)|go:"GO:1990913"(sperm head plasma membrane)|go:"GO:1990917"(ooplasm)|go:"GO:2000010"(positive regulation of protein localization to cell surface)|interpro:IPR001404(Heat shock protein Hsp90)|interpro:IPR003594(ATP-binding region, ATPase-like)|interpro:IPR019805|interpro:IPR020568|interpro:IPR020575|interpro:IPR036890|interpro:IPR037196|mint:P34058|reactome:R-RNO-168928|reactome:R-RNO-2029482|reactome:R-RNO-3371497|reactome:R-RNO-3371511|reactome:R-RNO-3371568|reactome:R-RNO-3371571|reactome:R-RNO-399954|reactome:R-RNO-6798695|reactome:R-RNO-844456|reactome:R-RNO-8852276|reactome:R-RNO-8937144|reactome:R-RNO-8939211|reactome:R-RNO-9013418|reactome:R-RNO-9018519	-	-	-	figure legend:st1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10116(rat-hippocampus)|taxid:10116(Rattus norvegicus hippocampal neurons)	-	2020/10/30	2020/10/30	rogid:DtE+ZXAZKdCMvUW5K+jXQ5bH07M10116	rogid:5/MXDESVXdwuWna0s87Ap19aLMA10116	rigid:zzsc1zNhBb5nwIRPeFpYOKgC3M8	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q5XIE8	uniprotkb:P82995	intact:EBI-15348306|ensembl:ENSRNOP00000023037	intact:EBI-919629|uniprotkb:Q91XW0|ensembl:ENSRNOP00000009556|ensembl:ENSRNOP00000075715	psi-mi:itm2b_rat(display_long)|uniprotkb:Itm2b(gene name)|psi-mi:Itm2b(display_short)|uniprotkb:Immature BRI2(gene name synonym)|uniprotkb:Transmembrane protein BRI(gene name synonym)	psi-mi:hs90a_rat(display_long)|uniprotkb:Hsp90aa1(gene name)|psi-mi:Hsp90aa1(display_short)|uniprotkb:Hspca(gene name synonym)|uniprotkb:Heat shock 86 kDa(gene name synonym)|uniprotkb:Hsp86(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Martins et al. (2018)	imex:IM-28469|pubmed:29476059	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26440627|imex:IM-28469-5	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSRNOG00000016271(gene)|ensembl:ENSRNOT00000023037(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001540"(amyloid-beta binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0010008"(endosome membrane)|go:"GO:0030660"(Golgi-associated vesicle membrane)|go:"GO:0031301"(integral component of organelle membrane)|go:"GO:0042985"(negative regulation of amyloid precursor protein biosynthetic process)|interpro:IPR007084(BRICHOS)|interpro:IPR040145|mint:Q5XIE8|refseq:NP_001006964.1|rgd:620727	refseq:XP_008763191.1|rgd:631409|refseq:NP_786937.1|ensembl:ENSRNOG00000007219(gene)|ensembl:ENSRNOG00000059714(gene)|ensembl:ENSRNOT00000009556(transcript)|ensembl:ENSRNOT00000086310(transcript)|go:"GO:0001764"(neuron migration)|go:"GO:0001934"(positive regulation of protein phosphorylation)|go:"GO:0002134"(UTP binding)|go:"GO:0002135"(CTP binding)|go:"GO:0002218"(activation of innate immune response)|go:"GO:0002230"(positive regulation of defense response to virus by host)|go:"GO:0003009"(skeletal muscle contraction)|go:"GO:0003729"(mRNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005525"(GTP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006457"(protein folding)|go:"GO:0007004"(telomere maintenance via telomerase)|go:"GO:0009408"(response to heat)|go:"GO:0009409"(response to cold)|go:"GO:0009651"(response to salt stress)|go:"GO:0009986"(cell surface)|go:"GO:0010592"(positive regulation of lamellipodium assembly)|go:"GO:0010659"(cardiac muscle cell apoptotic process)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0017098"(sulfonylurea receptor binding)|go:"GO:0019903"(protein phosphatase binding)|go:"GO:0021955"(central nervous system neuron axonogenesis)|go:"GO:0030010"(establishment of cell polarity)|go:"GO:0030235"(nitric-oxide synthase regulator activity)|go:"GO:0030911"(TPR domain binding)|go:"GO:0031396"(regulation of protein ubiquitination)|go:"GO:0031526"(brush border membrane)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032273"(positive regulation of protein polymerization)|go:"GO:0032564"(dATP binding)|go:"GO:0032728"(positive regulation of interferon-beta production)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033138"(positive regulation of peptidyl-serine phosphorylation)|go:"GO:0034605"(cellular response to heat)|go:"GO:0036126"(sperm flagellum)|go:"GO:0042220"(response to cocaine)|go:"GO:0042307"(positive regulation of protein import into nucleus)|go:"GO:0042470"(melanosome)|go:"GO:0042493"|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0043005"(neuron projection)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043202"(lysosomal lumen)|go:"GO:0043209"(myelin sheath)|go:"GO:0043627"(response to estrogen)|go:"GO:0044183"(protein folding chaperone)|go:"GO:0044294"(dendritic growth cone)|go:"GO:0044295"(axonal growth cone)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0045040"(protein insertion into mitochondrial outer membrane)|go:"GO:0045429"(positive regulation of nitric oxide biosynthetic process)|go:"GO:0045793"(positive regulation of cell size)|go:"GO:0046677"(response to antibiotic)|go:"GO:0048156"(tau protein binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0048675"(axon extension)|go:"GO:0050821"(protein stabilization)|go:"GO:0051020"(GTPase binding)|go:"GO:0051022"(Rho GDP-dissociation inhibitor binding)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0051131"(chaperone-mediated protein complex assembly)|go:"GO:0051897"(positive regulation of protein kinase B signaling)|go:"GO:0051973"(positive regulation of telomerase activity)|go:"GO:0060452"(positive regulation of cardiac muscle contraction)|go:"GO:0061635"(regulation of protein complex stability)|go:"GO:0061684"(chaperone-mediated autophagy)|go:"GO:0062023"(collagen-containing extracellular matrix)|go:"GO:0070182"(DNA polymerase binding)|go:"GO:0097110"(scaffold protein binding)|go:"GO:0097226"(sperm mitochondrial sheath)|go:"GO:0097524"(sperm plasma membrane)|go:"GO:0097718"(disordered domain specific binding)|go:"GO:0098586"(cellular response to virus)|go:"GO:0140597"(protein carrier chaperone)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|go:"GO:1902949"(positive regulation of tau-protein kinase activity)|go:"GO:1903364"(positive regulation of cellular protein catabolic process)|go:"GO:1903827"|go:"GO:1905323"(telomerase holoenzyme complex assembly)|go:"GO:1990782"(protein tyrosine kinase binding)|interpro:IPR001404(Heat shock protein Hsp90)|interpro:IPR003594(ATP-binding region, ATPase-like)|interpro:IPR019805|interpro:IPR020568|interpro:IPR020575|interpro:IPR036890|interpro:IPR037196|mint:P82995|reactome:R-RNO-1227986|reactome:R-RNO-1474151|reactome:R-RNO-168928|reactome:R-RNO-2029482|reactome:R-RNO-203615|reactome:R-RNO-2565942|reactome:R-RNO-3371497|reactome:R-RNO-3371511|reactome:R-RNO-3371568|reactome:R-RNO-3371571|reactome:R-RNO-380259|reactome:R-RNO-380270|reactome:R-RNO-380284|reactome:R-RNO-380320|reactome:R-RNO-399954|reactome:R-RNO-4420097|reactome:R-RNO-5218920|reactome:R-RNO-5620912|reactome:R-RNO-5675482|reactome:R-RNO-6798695|reactome:R-RNO-8852276|reactome:R-RNO-8854518|reactome:R-RNO-8863795|reactome:R-RNO-8939211|reactome:R-RNO-9009391|reactome:R-RNO-9013418|reactome:R-RNO-9018519|reactome:R-RNO-9652282	-	-	-	figure legend:st1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10116(rat-hippocampus)|taxid:10116(Rattus norvegicus hippocampal neurons)	-	2020/10/30	2020/10/30	rogid:DtE+ZXAZKdCMvUW5K+jXQ5bH07M10116	rogid:tqpvMNNqRR42cL/lpXrgcqJh0NE10116	rigid:zzsc1zNhBb5nwIRPeFpYOKgC3M8	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q5XIE8	uniprotkb:P09606	intact:EBI-15348306|ensembl:ENSRNOP00000023037	intact:EBI-349265|uniprotkb:Q6P7Q9|ensembl:ENSRNOP00000065890	psi-mi:itm2b_rat(display_long)|uniprotkb:Itm2b(gene name)|psi-mi:Itm2b(display_short)|uniprotkb:Immature BRI2(gene name synonym)|uniprotkb:Transmembrane protein BRI(gene name synonym)	psi-mi:glna_rat(display_long)|uniprotkb:Glns(gene name synonym)|uniprotkb:Glul(gene name)|psi-mi:Glul(display_short)|uniprotkb:Glutamate--ammonia ligase(gene name synonym)|uniprotkb:Palmitoyltransferase GLUL(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Martins et al. (2018)	imex:IM-28469|pubmed:29476059	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26440627|imex:IM-28469-5	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSRNOG00000016271(gene)|ensembl:ENSRNOT00000023037(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001540"(amyloid-beta binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0010008"(endosome membrane)|go:"GO:0030660"(Golgi-associated vesicle membrane)|go:"GO:0031301"(integral component of organelle membrane)|go:"GO:0042985"(negative regulation of amyloid precursor protein biosynthetic process)|interpro:IPR007084(BRICHOS)|interpro:IPR040145|mint:Q5XIE8|refseq:NP_001006964.1|rgd:620727	rgd:2710|refseq:NP_058769.4|ensembl:ENSRNOG00000049560(gene)|ensembl:ENSRNOT00000075480(transcript)|go:"GO:0000287"(magnesium ion binding)|go:"GO:0001525"(angiogenesis)|go:"GO:0004356"(glutamate-ammonia ligase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005791"(rough endoplasmic reticulum)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006536"(glutamate metabolic process)|go:"GO:0006542"(glutamine biosynthetic process)|go:"GO:0008283"(cell population proliferation)|go:"GO:0009267"(cellular response to starvation)|go:"GO:0009749"(response to glucose)|go:"GO:0010594"(regulation of endothelial cell migration)|go:"GO:0016595"(glutamate binding)|go:"GO:0018345"(protein palmitoylation)|go:"GO:0019676"(ammonia assimilation cycle)|go:"GO:0019706"(protein-cysteine S-palmitoyltransferase activity)|go:"GO:0030145"(manganese ion binding)|go:"GO:0032024"(positive regulation of insulin secretion)|go:"GO:0032991"(protein-containing complex)|go:"GO:0042133"(neurotransmitter metabolic process)|go:"GO:0042254"(ribosome biogenesis)|go:"GO:0042802"(identical protein binding)|go:"GO:0042995"(cell projection)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0043679"(axon terminus)|go:"GO:0044297"(cell body)|go:"GO:0045503"(dynein light chain binding)|go:"GO:0050679"(positive regulation of epithelial cell proliferation)|go:"GO:0051968"(positive regulation of synaptic transmission, glutamatergic)|go:"GO:0097386"(glial cell projection)|go:"GO:1903670"(regulation of sprouting angiogenesis)|go:"GO:1904749"(regulation of protein localization to nucleolus)|interpro:IPR008146(Glutamine synthetase, catalytic region)|interpro:IPR008147(Glutamine synthetase, beta-Grasp)|interpro:IPR014746(Glutamine synthetase/guanido kinase, catalytic region)|interpro:IPR027302|interpro:IPR027303|interpro:IPR036651|mint:P09606|go:"GO:0043005"(neuron projection)|reactome:R-RNO-210455|reactome:R-RNO-8964539|go:"GO:0043204"(perikaryon)|go:"GO:0043209"(myelin sheath)	-	-	-	figure legend:st1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10116(rat-hippocampus)|taxid:10116(Rattus norvegicus hippocampal neurons)	-	2020/10/30	2020/10/30	rogid:DtE+ZXAZKdCMvUW5K+jXQ5bH07M10116	rogid:VN1L4Kl9yF9dxmvXpA3f1prv0tw10116	rigid:zzsc1zNhBb5nwIRPeFpYOKgC3M8	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q5XIE8	uniprotkb:P19491	intact:EBI-15348306|ensembl:ENSRNOP00000023037	intact:EBI-77718|uniprotkb:Q9R174	psi-mi:itm2b_rat(display_long)|uniprotkb:Itm2b(gene name)|psi-mi:Itm2b(display_short)|uniprotkb:Immature BRI2(gene name synonym)|uniprotkb:Transmembrane protein BRI(gene name synonym)	psi-mi:gria2_rat(display_long)|uniprotkb:Gria2(gene name)|psi-mi:Gria2(display_short)|uniprotkb:Glur2(gene name synonym)|uniprotkb:GluR-B(gene name synonym)|uniprotkb:GluR-K2(gene name synonym)|uniprotkb:Glutamate receptor ionotropic, AMPA 2(gene name synonym)|uniprotkb:AMPA-selective glutamate receptor 2(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Martins et al. (2018)	imex:IM-28469|pubmed:29476059	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26440627|imex:IM-28469-5	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSRNOG00000016271(gene)|ensembl:ENSRNOT00000023037(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001540"(amyloid-beta binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0010008"(endosome membrane)|go:"GO:0030660"(Golgi-associated vesicle membrane)|go:"GO:0031301"(integral component of organelle membrane)|go:"GO:0042985"(negative regulation of amyloid precursor protein biosynthetic process)|interpro:IPR007084(BRICHOS)|interpro:IPR040145|mint:Q5XIE8|refseq:NP_001006964.1|rgd:620727	go:"GO:0019901"(protein kinase binding)|go:"GO:0030165"(PDZ domain binding)|go:"GO:0030425"(dendrite)|go:"GO:0030426"(growth cone)|go:"GO:0030672"(synaptic vesicle membrane)|go:"GO:0031623"(receptor internalization)|go:"GO:0032279"(asymmetric synapse)|go:"GO:0032281"(AMPA glutamate receptor complex)|go:"GO:0032839"(dendrite cytoplasm)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035235"(ionotropic glutamate receptor signaling pathway)|go:"GO:0035254"(glutamate receptor binding)|go:"GO:0036477"(somatodendritic compartment)|go:"GO:0038023"(signaling receptor activity)|go:"GO:0042734"(presynaptic membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0043005"(neuron projection)|go:"GO:0043025"(neuronal cell body)|interpro:IPR028082|rcsb pdb:1FTJ|rcsb pdb:1FTK|rcsb pdb:1FTL|rcsb pdb:1FTM|rcsb pdb:1FTO|rcsb pdb:1FW0|rcsb pdb:1GR2|rcsb pdb:1LB8|rcsb pdb:1LB9|rcsb pdb:1LBB|rcsb pdb:1LBC|rcsb pdb:1M5B|rcsb pdb:1M5C|rcsb pdb:1M5D|rcsb pdb:1M5E|rcsb pdb:1M5F|rcsb pdb:1MM6|rcsb pdb:1MM7|rcsb pdb:1MQD|rcsb pdb:1MQG|rcsb pdb:1MQH|rcsb pdb:1MQI|rcsb pdb:1MQJ|rcsb pdb:1MS7|rcsb pdb:1MXU|rcsb pdb:1MXV|rcsb pdb:1MXW|rcsb pdb:1MXX|rcsb pdb:1MXY|rcsb pdb:1MXZ|rcsb pdb:1MY0|rcsb pdb:1MY1|rcsb pdb:1MY2|rcsb pdb:1MY3|go:"GO:0043195"(terminal bouton)|go:"GO:0043197"(dendritic spine)|go:"GO:0043198"(dendritic shaft)|go:"GO:0043204"(perikaryon)|go:"GO:0045184"(establishment of protein localization)|go:"GO:0045202"(synapse)|go:"GO:0045211"(postsynaptic membrane)|go:"GO:0050806"(positive regulation of synaptic transmission)|go:"GO:0051117"(ATPase binding)|go:"GO:0051262"(protein tetramerization)|go:"GO:0051966"(regulation of synaptic transmission, glutamatergic)|go:"GO:0060992"(response to fungicide)|go:"GO:0097060"(synaptic membrane)|go:"GO:0098685"(Schaffer collateral - CA1 synapse)|go:"GO:0098839"(postsynaptic density membrane)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099055"(integral component of postsynaptic membrane)|go:"GO:0099056"(integral component of presynaptic membrane)|go:"GO:0099061"(integral component of postsynaptic density membrane)|go:"GO:0099544"(perisynaptic space)|go:"GO:1904315"(transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential)|interpro:IPR001320(Ionotropic glutamate receptor)|interpro:IPR001508(NMDA receptor)|interpro:IPR001828(Extracellular ligand-binding receptor)|interpro:IPR019594|go:"GO:0001540"(amyloid-beta binding)|go:"GO:0001919"(regulation of receptor recycling)|go:"GO:0004970"(ionotropic glutamate receptor activity)|go:"GO:0004971"(AMPA glutamate receptor activity)|go:"GO:0000149"(SNARE binding)|go:"GO:0005234"(extracellularly glutamate-gated ion channel activity)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0007268"(chemical synaptic transmission)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0008092"(cytoskeletal protein binding)|go:"GO:0008328"(ionotropic glutamate receptor complex)|go:"GO:0009986"(cell surface)|go:"GO:0010226"(response to lithium ion)|go:"GO:0014069"(postsynaptic density)|go:"GO:0015276"(ligand-gated ion channel activity)|go:"GO:0015277"(kainate selective glutamate receptor activity)|go:"GO:0016020"(membrane)|go:"GO:0019865"(immunoglobulin binding)|rcsb pdb:1MY4|rcsb pdb:1N0T|rcsb pdb:1NNK|rcsb pdb:1NNP|rcsb pdb:1P1N|rcsb pdb:1P1O|rcsb pdb:1P1Q|rcsb pdb:1P1U|rcsb pdb:1P1W|rcsb pdb:1SYH|rcsb pdb:1SYI|rcsb pdb:1WVJ|rcsb pdb:1XHY|rcsb pdb:2AIX|rcsb pdb:2AL4|rcsb pdb:2AL5|rcsb pdb:2ANJ|rcsb pdb:2CMO|rcsb pdb:2GFE|rcsb pdb:2I3V|rcsb pdb:2I3W|rcsb pdb:2P2A|rcsb pdb:2UXA|rcsb pdb:2XX7|rcsb pdb:2XX8|rcsb pdb:2XX9|rcsb pdb:2XXH|rcsb pdb:2XXI|rcsb pdb:3B6Q|rcsb pdb:5NIH|rcsb pdb:5NS9|rcsb pdb:5O9A|rcsb pdb:5OEW|rcsb pdb:5VHW|rcsb pdb:5VHX|rcsb pdb:5VHY|rcsb pdb:5VHZ|rcsb pdb:5VOT|rcsb pdb:5VOU|rcsb pdb:5VOV|rcsb pdb:5WEK|rcsb pdb:5WEL|rcsb pdb:5WEM|rcsb pdb:5WEN|rcsb pdb:5WEO|rcsb pdb:6DLZ|rcsb pdb:6DM0|rcsb pdb:6DM1|rcsb pdb:6FAZ|rcsb pdb:6FQG|rcsb pdb:6FQH|rcsb pdb:6FQI|rcsb pdb:6FQJ|rcsb pdb:6FQK|rcsb pdb:6GIV|rcsb pdb:6GL4|rcsb pdb:6HC9|rcsb pdb:6HCA|rcsb pdb:6HCB|rcsb pdb:6HCC|rcsb pdb:6HCH|rcsb pdb:6NJL|rcsb pdb:6NJM|rcsb pdb:6NJN|rcsb pdb:6O9G|rcsb pdb:6PEQ|rcsb pdb:6Q54|rcsb pdb:6Q60|rcsb pdb:6QKC|rcsb pdb:6QKZ|rcsb pdb:3B6T|rcsb pdb:3B6W|rcsb pdb:3B7D|rcsb pdb:3BBR|rcsb pdb:3BFT|rcsb pdb:3BFU|rcsb pdb:3BKI|rcsb pdb:3DP6|rcsb pdb:3H03|rcsb pdb:3H06|rcsb pdb:3H5V|rcsb pdb:3H5W|rcsb pdb:3H6T|rcsb pdb:3H6U|rcsb pdb:3H6V|rcsb pdb:3H6W|rcsb pdb:3HSY|rcsb pdb:3IJO|rcsb pdb:3IJX|rcsb pdb:3IK6|rcsb pdb:3IL1|rcsb pdb:3ILT|rcsb pdb:3ILU|rcsb pdb:3KG2|rcsb pdb:3KGC|rcsb pdb:3LSF|rcsb pdb:3LSL|rcsb pdb:3M3L|rcsb pdb:3N6V|rcsb pdb:3O28|rcsb pdb:3O29|rcsb pdb:3O2A|rcsb pdb:3O2J|rcsb pdb:3O6G|rcsb pdb:3O6H|rcsb pdb:3O6I|rcsb pdb:3PD8|rcsb pdb:3PD9|rcsb pdb:3PMV|rcsb pdb:3PMW|rcsb pdb:3PMX|rcsb pdb:6RUQ|rcsb pdb:6U5S|rcsb pdb:6U6I|rcsb pdb:6UCB|rcsb pdb:6UD4|rcsb pdb:6UD8|rcsb pdb:6XSR|rcsb pdb:6YK2|rcsb pdb:6YK3|rcsb pdb:6YK4|rcsb pdb:6YK5|rcsb pdb:6YK6|rcsb pdb:7OCA|rcsb pdb:7OCC|rcsb pdb:7OCD|rcsb pdb:7OCE|rcsb pdb:7OCF|reactome:R-RNO-399710|reactome:R-RNO-416993|reactome:R-RNO-438066|rcsb pdb:3RTF|rcsb pdb:3RTW|rcsb pdb:3T93|rcsb pdb:3T96|rcsb pdb:3T9H|rcsb pdb:3T9U|rcsb pdb:3T9V|rcsb pdb:3T9X|rcsb pdb:3TDJ|rcsb pdb:3TKD|rcsb pdb:3TZA|rcsb pdb:4FAT|rcsb pdb:4G8M|rcsb pdb:4GXS|rcsb pdb:4H8J|rcsb pdb:4IGT|rcsb pdb:4ISU|rcsb pdb:4IY5|rcsb pdb:4IY6|rcsb pdb:4L17|rcsb pdb:4LZ5|rcsb pdb:4LZ7|rcsb pdb:4LZ8|rcsb pdb:4N07|rcsb pdb:4O3A|rcsb pdb:4O3B|rcsb pdb:4O3C|rcsb pdb:4Q30|rcsb pdb:4U1O|rcsb pdb:4U1W|rcsb pdb:4U1X|rcsb pdb:4U1Y|rcsb pdb:4U1Z|rcsb pdb:4U21|rcsb pdb:4U22|rcsb pdb:4U23|rcsb pdb:4U2P|rcsb pdb:4U2Q|rcsb pdb:4U2R|rcsb pdb:4U4F|rcsb pdb:4U4G|rcsb pdb:4U4S|rcsb pdb:4U4X|rcsb pdb:4U5B|rcsb pdb:4U5C|rcsb pdb:4U5D|rcsb pdb:4U5E|rcsb pdb:4U5F|rcsb pdb:4UQ6|rcsb pdb:4UQJ|rcsb pdb:4UQK|rcsb pdb:4X48|rcsb pdb:4YMA|rcsb pdb:4YU0|rcsb pdb:4Z0I|rcsb pdb:5BUU|rcsb pdb:5CBR|rcsb pdb:5CBS|rcsb pdb:5ELV|rcsb pdb:5FHM|rcsb pdb:5FHN|rcsb pdb:5FHO|rcsb pdb:5FTH|rcsb pdb:5FTI|rcsb pdb:5FWX|rcsb pdb:5FWY|rcsb pdb:5IDE|rcsb pdb:5IDF|rcsb pdb:5JEI|rcsb pdb:5KBS|rcsb pdb:5KBT|rcsb pdb:5KBU|rcsb pdb:5KBV|rcsb pdb:5KK2|rcsb pdb:5L1B|rcsb pdb:5L1E|rcsb pdb:5L1F|rcsb pdb:5L1G|rcsb pdb:5L1H|rcsb pdb:5N6P|rcsb pdb:5NG9|refseq:NP_001077280.1|refseq:NP_058957.1|rgd:61862|mint:P19491|dip:DIP-30952N	-	-	-	figure legend:st1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10116(rat-hippocampus)|taxid:10116(Rattus norvegicus hippocampal neurons)	-	2020/10/30	2020/10/30	rogid:DtE+ZXAZKdCMvUW5K+jXQ5bH07M10116	rogid:zeQRRvspsIuRyA9kKA7kyIr8HqE10116	rigid:zzsc1zNhBb5nwIRPeFpYOKgC3M8	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q5XIE8	uniprotkb:P47819	intact:EBI-15348306|ensembl:ENSRNOP00000023037	intact:EBI-931216|uniprotkb:Q7TQ31|uniprotkb:Q9R1Q3|uniprotkb:Q9Z2S0|uniprotkb:A7REI0|ensembl:ENSRNOP00000032389	psi-mi:itm2b_rat(display_long)|uniprotkb:Itm2b(gene name)|psi-mi:Itm2b(display_short)|uniprotkb:Immature BRI2(gene name synonym)|uniprotkb:Transmembrane protein BRI(gene name synonym)	psi-mi:gfap_rat(display_long)|uniprotkb:Gfap(gene name)|psi-mi:Gfap(display_short)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Martins et al. (2018)	imex:IM-28469|pubmed:29476059	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26440627|imex:IM-28469-5	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSRNOG00000016271(gene)|ensembl:ENSRNOT00000023037(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001540"(amyloid-beta binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0010008"(endosome membrane)|go:"GO:0030660"(Golgi-associated vesicle membrane)|go:"GO:0031301"(integral component of organelle membrane)|go:"GO:0042985"(negative regulation of amyloid precursor protein biosynthetic process)|interpro:IPR007084(BRICHOS)|interpro:IPR040145|mint:Q5XIE8|refseq:NP_001006964.1|rgd:620727	rgd:2679|refseq:NP_058705.2|ensembl:ENSRNOG00000002919(gene)|ensembl:ENSRNOT00000034401(transcript)|go:"GO:0005178"(integrin binding)|go:"GO:0005200"(structural constituent of cytoskeleton)|go:"GO:0005737"(cytoplasm)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005882"(intermediate filament)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0009611"(response to wounding)|go:"GO:0010467"(gene expression)|go:"GO:0010625"(positive regulation of Schwann cell proliferation)|go:"GO:0010977"(negative regulation of neuron projection development)|go:"GO:0014002"(astrocyte development)|go:"GO:0016020"(membrane)|go:"GO:0019900"(kinase binding)|go:"GO:0030198"(extracellular matrix organization)|go:"GO:0031102"(neuron projection regeneration)|go:"GO:0042802"(identical protein binding)|go:"GO:0042995"(cell projection)|go:"GO:0044297"(cell body)|go:"GO:0045103"(intermediate filament-based process)|go:"GO:0045109"(intermediate filament organization)|go:"GO:0051580"(regulation of neurotransmitter uptake)|go:"GO:0060020"(Bergmann glial cell differentiation)|go:"GO:0060252"(positive regulation of glial cell proliferation)|go:"GO:0060291"(long-term synaptic potentiation)|go:"GO:0070779"(D-aspartate import across plasma membrane)|go:"GO:0097386"(glial cell projection)|go:"GO:0097449"(astrocyte projection)|go:"GO:0097450"(astrocyte end-foot)|go:"GO:0098574"(cytoplasmic side of lysosomal membrane)|go:"GO:1904714"(regulation of chaperone-mediated autophagy)|interpro:IPR006821(Intermediate filament, DNA-binding region)|interpro:IPR018039|interpro:IPR027701|interpro:IPR039008|mint:P47819	-	-	-	figure legend:st1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10116(rat-hippocampus)|taxid:10116(Rattus norvegicus hippocampal neurons)	-	2020/10/30	2020/10/30	rogid:DtE+ZXAZKdCMvUW5K+jXQ5bH07M10116	rogid:ougdJqiJZjrvDV1vfVnCwcx9cFU10116	rigid:zzsc1zNhBb5nwIRPeFpYOKgC3M8	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q5XIE8	uniprotkb:P08050	intact:EBI-15348306|ensembl:ENSRNOP00000023037	intact:EBI-476947|uniprotkb:Q53ZE1|ensembl:ENSRNOP00000001054	psi-mi:itm2b_rat(display_long)|uniprotkb:Itm2b(gene name)|psi-mi:Itm2b(display_short)|uniprotkb:Immature BRI2(gene name synonym)|uniprotkb:Transmembrane protein BRI(gene name synonym)	psi-mi:cxa1_rat(display_long)|uniprotkb:Gja1(gene name)|psi-mi:Gja1(display_short)|uniprotkb:Cxn-43(gene name synonym)|uniprotkb:Connexin-43(gene name synonym)|uniprotkb:Gap junction 43 kDa heart protein(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Martins et al. (2018)	imex:IM-28469|pubmed:29476059	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26440627|imex:IM-28469-5	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSRNOG00000016271(gene)|ensembl:ENSRNOT00000023037(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001540"(amyloid-beta binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0010008"(endosome membrane)|go:"GO:0030660"(Golgi-associated vesicle membrane)|go:"GO:0031301"(integral component of organelle membrane)|go:"GO:0042985"(negative regulation of amyloid precursor protein biosynthetic process)|interpro:IPR007084(BRICHOS)|interpro:IPR040145|mint:Q5XIE8|refseq:NP_001006964.1|rgd:620727	go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0030500"(regulation of bone mineralization)|go:"GO:0030660"(Golgi-associated vesicle membrane)|go:"GO:0032024"(positive regulation of insulin secretion)|go:"GO:0032277"(negative regulation of gonadotropin secretion)|go:"GO:0032355"(response to estradiol)|go:"GO:0032496"(response to lipopolysaccharide)|go:"GO:0032526"(response to retinoic acid)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034220"(ion transmembrane transport)|go:"GO:0034405"(response to fluid shear stress)|go:"GO:0034613"(cellular protein localization)|go:"GO:0034634"(glutathione transmembrane transporter activity)|go:"GO:0035050"(embryonic heart tube development)|go:"GO:0035437"(maintenance of protein localization in endoplasmic reticulum)|go:"GO:0042098"(T cell proliferation)|go:"GO:0042110"(T cell activation)|go:"GO:0030165"(PDZ domain binding)|ensembl:ENSRNOT00000001054(transcript)|go:"GO:0000132"(establishment of mitotic spindle orientation)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001649"(osteoblast differentiation)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0001764"(neuron migration)|go:"GO:0001937"(negative regulation of endothelial cell proliferation)|go:"GO:0001947"(heart looping)|ensembl:ENSRNOG00000000805(gene)|go:"GO:0002070"(epithelial cell maturation)|go:"GO:0002088"(lens development in camera-type eye)|go:"GO:0002544"(chronic inflammatory response)|go:"GO:0002931"(response to ischemia)|go:"GO:0003104"(positive regulation of glomerular filtration)|go:"GO:0003158"(endothelium development)|go:"GO:0042311"(vasodilation)|go:"GO:0042733"(embryonic digit morphogenesis)|go:"GO:0042908"(xenobiotic transport)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0043292"(contractile fiber)|go:"GO:0043403"(skeletal muscle tissue regeneration)|go:"GO:0043434"(response to peptide hormone)|go:"GO:0044291"(cell-cell contact zone)|go:"GO:0045121"(membrane raft)|go:"GO:0045216"(cell-cell junction organization)|go:"GO:0045732"(positive regulation of protein catabolic process)|go:"GO:0045844"(positive regulation of striated muscle tissue development)|go:"GO:0045907"(positive regulation of vasoconstriction)|go:"GO:0046697"(decidualization)|go:"GO:0046849"(bone remodeling)|go:"GO:0046850"(regulation of bone remodeling)|go:"GO:0048487"(beta-tubulin binding)|go:"GO:0048514"(blood vessel morphogenesis)|go:"GO:0048812"(neuron projection morphogenesis)|go:"GO:0051924"(regulation of calcium ion transport)|go:"GO:0055077"(gap junction hemi-channel activity)|go:"GO:0055085"(transmembrane transport)|go:"GO:0060044"(negative regulation of cardiac muscle cell proliferation)|go:"GO:0060156"(milk ejection reflex)|go:"GO:0060307"(regulation of ventricular cardiac muscle cell membrane repolarization)|go:"GO:0060348"(bone development)|go:"GO:0060371"(regulation of atrial cardiac muscle cell membrane depolarization)|go:"GO:0060373"(regulation of ventricular cardiac muscle cell membrane depolarization)|go:"GO:0061045"(negative regulation of wound healing)|go:"GO:0061337"(cardiac conduction)|go:"GO:0070160"(tight junction)|go:"GO:0071253"(connexin binding)|go:"GO:0071260"(cellular response to mechanical stimulus)|go:"GO:0071374"(cellular response to parathyroid hormone stimulus)|go:"GO:0071467"(cellular response to pH)|go:"GO:0097110"(scaffold protein binding)|go:"GO:0003294"(atrial ventricular junction remodeling)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005243"(gap junction channel activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005764"(lysosome)|go:"GO:0005768"(endosome)|go:"GO:0005769"(early endosome)|go:"GO:0005770"(late endosome)|go:"GO:0005771"(multivesicular body)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0005882"(intermediate filament)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0097718"(disordered domain specific binding)|go:"GO:0099111"(microtubule-based transport)|go:"GO:1904646"(cellular response to amyloid-beta)|go:"GO:0120162"(positive regulation of cold-induced thermogenesis)|go:"GO:1904707"(positive regulation of vascular associated smooth muscle cell proliferation)|go:"GO:1905332"(positive regulation of morphogenesis of an epithelium)|go:"GO:1905772"(positive regulation of mesodermal cell differentiation)|go:"GO:0140115"(export across plasma membrane)|go:"GO:1905867"(epididymis development)|go:"GO:1901164"(negative regulation of trophoblast cell migration)|go:"GO:1990782"(protein tyrosine kinase binding)|go:"GO:2000279"(negative regulation of DNA biosynthetic process)|go:"GO:2000648"(positive regulation of stem cell proliferation)|go:"GO:2000810"(regulation of bicellular tight junction assembly)|go:"GO:2000987"(positive regulation of behavioral fear response)|interpro:IPR000500(Connexins)|go:"GO:1903763"(gap junction channel activity involved in cell communication by electrical coupling)|interpro:IPR002261("Gap junction alpha-1 protein (Cx43)")|interpro:IPR013092(Connexin, N-terminal)|interpro:IPR013124("Gap junction alpha-1 protein (Cx43), C-terminal")|interpro:IPR017990|interpro:IPR019570|interpro:IPR034634|interpro:IPR035091|interpro:IPR038359|mint:P08050|rcsb pdb:1R5S|rcsb pdb:2N8T|rcsb pdb:3CYY|reactome:R-RNO-190840|reactome:R-RNO-190861|reactome:R-RNO-190873|reactome:R-RNO-191650|reactome:R-RNO-196025|reactome:R-RNO-9013406|go:"GO:0005916"(fascia adherens)|go:"GO:0008584"(male gonad development)|go:"GO:0009268"(response to pH)|go:"GO:0005921"(gap junction)|go:"GO:0005922"(connexin complex)|go:"GO:0009749"(response to glucose)|go:"GO:0010232"(vascular transport)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0010643"(cell communication by chemical coupling)|go:"GO:0010644"(cell communication by electrical coupling)|go:"GO:0010649"(regulation of cell communication by electrical coupling)|go:"GO:0010652"(positive regulation of cell communication by chemical coupling)|go:"GO:0014047"(glutamate secretion)|go:"GO:0014704"(intercalated disc)|go:"GO:0015075"(ion transmembrane transporter activity)|go:"GO:0015562"(efflux transmembrane transporter activity)|go:"GO:0015631"(tubulin binding)|go:"GO:0015867"(ATP transport)|go:"GO:0016020"(membrane)|go:"GO:0016264"(gap junction assembly)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0016328"(lateral plasma membrane)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0006915"(apoptotic process)|go:"GO:0022898"(regulation of transmembrane transporter activity)|go:"GO:0007154"(cell communication)|go:"GO:0030054"(cell junction)|go:"GO:0007165"(signal transduction)|go:"GO:0007204"(positive regulation of cytosolic calcium ion concentration)|go:"GO:0007267"(cell-cell signaling)|go:"GO:0007283"(spermatogenesis)|go:"GO:0007507"(heart development)|go:"GO:0007512"(adult heart development)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0008016"(regulation of heart contraction)|go:"GO:0008285"(negative regulation of cell population proliferation)|rgd:2690|refseq:NP_036699.1|dip:DIP-34793N	-	-	-	figure legend:st1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10116(rat-hippocampus)|taxid:10116(Rattus norvegicus hippocampal neurons)	-	2020/10/30	2020/10/30	rogid:DtE+ZXAZKdCMvUW5K+jXQ5bH07M10116	rogid:qRGPHCApRj9/xiPxo1KW9D/xE5w10116	rigid:zzsc1zNhBb5nwIRPeFpYOKgC3M8	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q5XIE8	uniprotkb:P31596	intact:EBI-15348306|ensembl:ENSRNOP00000023037	intact:EBI-2649895	psi-mi:itm2b_rat(display_long)|uniprotkb:Itm2b(gene name)|psi-mi:Itm2b(display_short)|uniprotkb:Immature BRI2(gene name synonym)|uniprotkb:Transmembrane protein BRI(gene name synonym)	psi-mi:eaa2_rat(display_long)|uniprotkb:Slc1a2(gene name)|psi-mi:Slc1a2(display_short)|uniprotkb:Eaat2(gene name synonym)|uniprotkb:Glt1(gene name synonym)|uniprotkb:Sodium-dependent glutamate/aspartate transporter 2(gene name synonym)|uniprotkb:GLT-1(gene name synonym)|uniprotkb:Solute carrier family 1 member 2(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Martins et al. (2018)	imex:IM-28469|pubmed:29476059	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26440627|imex:IM-28469-5	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSRNOG00000016271(gene)|ensembl:ENSRNOT00000023037(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001540"(amyloid-beta binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0010008"(endosome membrane)|go:"GO:0030660"(Golgi-associated vesicle membrane)|go:"GO:0031301"(integral component of organelle membrane)|go:"GO:0042985"(negative regulation of amyloid precursor protein biosynthetic process)|interpro:IPR007084(BRICHOS)|interpro:IPR040145|mint:Q5XIE8|refseq:NP_001006964.1|rgd:620727	mint:P31596|rgd:3697|refseq:NP_058911.2|interpro:IPR001991("Sodium:dicarboxylate symporter")|interpro:IPR018107|refseq:NP_001289018.1|go:"GO:0005313"(L-glutamate transmembrane transporter activity)|go:"GO:0005314"(high-affinity glutamate transmembrane transporter activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006750"(glutathione biosynthetic process)|go:"GO:0006836"(neurotransmitter transport)|go:"GO:0007399"(nervous system development)|go:"GO:0007632"(visual behavior)|go:"GO:0008509"(anion transmembrane transporter activity)|go:"GO:0009416"(response to light stimulus)|go:"GO:0009611"(response to wounding)|go:"GO:0009986"(cell surface)|go:"GO:0010259"(multicellular organism aging)|go:"GO:0015501"("glutamate:sodium symporter activity")|go:"GO:0015813"(L-glutamate transmembrane transport)|go:"GO:0016020"(membrane)|go:"GO:0021537"(telencephalon development)|go:"GO:0030424"(axon)|go:"GO:0030534"(adult behavior)|go:"GO:0030673"(axolemma)|go:"GO:0031668"(cellular response to extracellular stimulus)|go:"GO:0031982"(vesicle)|go:"GO:0033229"(cysteine transmembrane transporter activity)|go:"GO:0035264"(multicellular organism growth)|go:"GO:0042493"|go:"GO:0042734"(presynaptic membrane)|go:"GO:0043005"(neuron projection)|go:"GO:0043197"(dendritic spine)|go:"GO:0043198"(dendritic shaft)|go:"GO:0043200"(response to amino acid)|go:"GO:0044297"(cell body)|go:"GO:0044306"(neuron projection terminus)|go:"GO:0045121"(membrane raft)|go:"GO:0045202"(synapse)|go:"GO:0046326"(positive regulation of glucose import)|go:"GO:0046872"(metal ion binding)|go:"GO:0070207"(protein homotrimerization)|go:"GO:0070779"(D-aspartate import across plasma membrane)|go:"GO:0071314"(cellular response to cocaine)|go:"GO:0097449"(astrocyte projection)|go:"GO:0098656"(anion transmembrane transport)|go:"GO:0098712"(L-glutamate import across plasma membrane)|go:"GO:0098796"(membrane protein complex)|go:"GO:0098810"(neurotransmitter reuptake)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099056"(integral component of presynaptic membrane)|reactome:R-RNO-210455|reactome:R-RNO-210500|reactome:R-RNO-425393|interpro:IPR036458	-	-	-	figure legend:st1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10116(rat-hippocampus)|taxid:10116(Rattus norvegicus hippocampal neurons)	-	2020/10/30	2020/10/30	rogid:DtE+ZXAZKdCMvUW5K+jXQ5bH07M10116	rogid:JednhWybRDznXCugAtjbnX/1JmM10116	rigid:zzsc1zNhBb5nwIRPeFpYOKgC3M8	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q5XIE8	uniprotkb:P24942	intact:EBI-15348306|ensembl:ENSRNOP00000023037	intact:EBI-26373259|uniprotkb:Q9JK43	psi-mi:itm2b_rat(display_long)|uniprotkb:Itm2b(gene name)|psi-mi:Itm2b(display_short)|uniprotkb:Immature BRI2(gene name synonym)|uniprotkb:Transmembrane protein BRI(gene name synonym)	psi-mi:eaa1_rat(display_long)|uniprotkb:Glial glutamate transporter(gene name synonym)|uniprotkb:Sodium-dependent glutamate/aspartate transporter 1(gene name synonym)|uniprotkb:Solute carrier family 1 member 3(gene name synonym)|uniprotkb:Slc1a3(gene name)|psi-mi:Slc1a3(display_short)|uniprotkb:Eaat1(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Martins et al. (2018)	imex:IM-28469|pubmed:29476059	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26440627|imex:IM-28469-5	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSRNOG00000016271(gene)|ensembl:ENSRNOT00000023037(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001540"(amyloid-beta binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0010008"(endosome membrane)|go:"GO:0030660"(Golgi-associated vesicle membrane)|go:"GO:0031301"(integral component of organelle membrane)|go:"GO:0042985"(negative regulation of amyloid precursor protein biosynthetic process)|interpro:IPR007084(BRICHOS)|interpro:IPR040145|mint:Q5XIE8|refseq:NP_001006964.1|rgd:620727	go:"GO:0015172"(acidic amino acid transmembrane transporter activity)|go:"GO:0015501"("glutamate:sodium symporter activity")|go:"GO:0015813"(L-glutamate transmembrane transport)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016595"(glutamate binding)|go:"GO:0016597"(amino acid binding)|go:"GO:0021545"(cranial nerve development)|go:"GO:0031223"(auditory behavior)|go:"GO:0042493"|go:"GO:0042995"(cell projection)|go:"GO:0043005"(neuron projection)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043197"(dendritic spine)|go:"GO:0043490"(malate-aspartate shuttle)|go:"GO:0045202"(synapse)|go:"GO:0046677"(response to antibiotic)|go:"GO:0046872"(metal ion binding)|go:"GO:0048667"(cell morphogenesis involved in neuron differentiation)|go:"GO:0050806"(positive regulation of synaptic transmission)|go:"GO:0050885"(neuromuscular process controlling balance)|go:"GO:0051938"(L-glutamate import)|go:"GO:0070779"(D-aspartate import across plasma membrane)|go:"GO:0071314"(cellular response to cocaine)|go:"GO:0071805"(potassium ion transmembrane transport)|go:"GO:0071944"(cell periphery)|go:"GO:0098712"(L-glutamate import across plasma membrane)|go:"GO:0005313"(L-glutamate transmembrane transporter activity)|go:"GO:0005314"(high-affinity glutamate transmembrane transporter activity)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006836"(neurotransmitter transport)|go:"GO:0006883"(cellular sodium ion homeostasis)|go:"GO:0007605"(sensory perception of sound)|go:"GO:0009416"(response to light stimulus)|go:"GO:0009449"(gamma-aminobutyric acid biosynthetic process)|go:"GO:0009611"(response to wounding)|go:"GO:0009925"(basal plasma membrane)|go:"GO:0009986"(cell surface)|go:"GO:0010035"(response to inorganic substance)|go:"GO:0098796"(membrane protein complex)|go:"GO:0140009"(L-aspartate import across plasma membrane)|go:"GO:1902476"(chloride transmembrane transport)|reactome:R-RNO-210455|reactome:R-RNO-210500|reactome:R-RNO-425393|rgd:3698|mint:P24942|refseq:NP_001276870.1|refseq:NP_001276871.1|refseq:NP_001276872.1|refseq:NP_062098.1|interpro:IPR001991("Sodium:dicarboxylate symporter")|interpro:IPR018107|interpro:IPR036458	-	-	-	figure legend:st1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10116(rat-hippocampus)|taxid:10116(Rattus norvegicus hippocampal neurons)	-	2020/10/30	2020/10/30	rogid:DtE+ZXAZKdCMvUW5K+jXQ5bH07M10116	rogid:c22nOB/elZ8k3t1KJiZ3jyW+aSs10116	rigid:zzsc1zNhBb5nwIRPeFpYOKgC3M8	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q5XIE8	uniprotkb:Q66HD0	intact:EBI-15348306|ensembl:ENSRNOP00000023037	intact:EBI-6249734|uniprotkb:A6IFJ6	psi-mi:itm2b_rat(display_long)|uniprotkb:Itm2b(gene name)|psi-mi:Itm2b(display_short)|uniprotkb:Immature BRI2(gene name synonym)|uniprotkb:Transmembrane protein BRI(gene name synonym)	psi-mi:enpl_rat(display_long)|uniprotkb:Hsp90b1(gene name)|psi-mi:Hsp90b1(display_short)|uniprotkb:Grp94(gene name synonym)|uniprotkb:Tra1(gene name synonym)|uniprotkb:94 kDa glucose-regulated protein(gene name synonym)|uniprotkb:Heat shock protein 90 kDa beta member 1(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Martins et al. (2018)	imex:IM-28469|pubmed:29476059	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26440627|imex:IM-28469-5	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSRNOG00000016271(gene)|ensembl:ENSRNOT00000023037(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001540"(amyloid-beta binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0010008"(endosome membrane)|go:"GO:0030660"(Golgi-associated vesicle membrane)|go:"GO:0031301"(integral component of organelle membrane)|go:"GO:0042985"(negative regulation of amyloid precursor protein biosynthetic process)|interpro:IPR007084(BRICHOS)|interpro:IPR040145|mint:Q5XIE8|refseq:NP_001006964.1|rgd:620727	mint:Q66HD0|rgd:1310482|refseq:NP_001012197.2|interpro:IPR003594(ATP-binding region, ATPase-like)|interpro:IPR019805|interpro:IPR001404(Heat shock protein Hsp90)|interpro:IPR020575|interpro:IPR020568|go:"GO:0001666"(response to hypoxia)|go:"GO:0003723"(RNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005788"(endoplasmic reticulum lumen)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005790"(smooth endoplasmic reticulum)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006457"(protein folding)|go:"GO:0019903"(protein phosphatase binding)|go:"GO:0030433"(ubiquitin-dependent ERAD pathway)|go:"GO:0030496"(midbody)|go:"GO:0030970"(retrograde protein transport, ER to cytosol)|go:"GO:0031247"(actin rod assembly)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033018"(sarcoplasmic reticulum lumen)|go:"GO:0034663"(endoplasmic reticulum chaperone complex)|go:"GO:0042470"(melanosome)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043666"(regulation of phosphoprotein phosphatase activity)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0050750"(low-density lipoprotein particle receptor binding)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0071287"(cellular response to manganese ion)|go:"GO:0071318"(cellular response to ATP)|reactome:R-RNO-1679131|reactome:R-RNO-3000480|reactome:R-RNO-381426|reactome:R-RNO-6785807|reactome:R-RNO-8957275|interpro:IPR036890|interpro:IPR037196	-	-	-	figure legend:st1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10116(rat-hippocampus)|taxid:10116(Rattus norvegicus hippocampal neurons)	-	2020/10/30	2020/10/30	rogid:DtE+ZXAZKdCMvUW5K+jXQ5bH07M10116	rogid:KSJbfWJ3pXbaBW15MDZ6syUs/4U10116	rigid:zzsc1zNhBb5nwIRPeFpYOKgC3M8	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q5XIE8	uniprotkb:Q5PPJ9	intact:EBI-15348306|ensembl:ENSRNOP00000023037	intact:EBI-8848640	psi-mi:itm2b_rat(display_long)|uniprotkb:Itm2b(gene name)|psi-mi:Itm2b(display_short)|uniprotkb:Immature BRI2(gene name synonym)|uniprotkb:Transmembrane protein BRI(gene name synonym)	psi-mi:shlb2_rat(display_long)|uniprotkb:Sh3glb2(gene name)|psi-mi:Sh3glb2(display_short)|uniprotkb:SH3 domain-containing GRB2-like protein B2(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Martins et al. (2018)	imex:IM-28469|pubmed:29476059	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26440627|imex:IM-28469-5	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSRNOG00000016271(gene)|ensembl:ENSRNOT00000023037(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001540"(amyloid-beta binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0010008"(endosome membrane)|go:"GO:0030660"(Golgi-associated vesicle membrane)|go:"GO:0031301"(integral component of organelle membrane)|go:"GO:0042985"(negative regulation of amyloid precursor protein biosynthetic process)|interpro:IPR007084(BRICHOS)|interpro:IPR040145|mint:Q5XIE8|refseq:NP_001006964.1|rgd:620727	mint:Q5PPJ9|interpro:IPR027267|interpro:IPR004148(BAR)|interpro:IPR001452(Src homology-3)|refseq:NP_001009692.1|rgd:1305886|refseq:XP_006233880.1|interpro:IPR035640|interpro:IPR036028|go:"GO:0005737"(cytoplasm)|go:"GO:0042802"(identical protein binding)	-	-	-	figure legend:st1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10116(rat-hippocampus)|taxid:10116(Rattus norvegicus hippocampal neurons)	-	2020/10/30	2020/10/30	rogid:DtE+ZXAZKdCMvUW5K+jXQ5bH07M10116	rogid:Zm8xh0SeU1baeRfRtOvo8uae/n810116	rigid:zzsc1zNhBb5nwIRPeFpYOKgC3M8	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q5XIE8	uniprotkb:P85834	intact:EBI-15348306|ensembl:ENSRNOP00000023037	intact:EBI-2640608|ensembl:ENSRNOP00000025203	psi-mi:itm2b_rat(display_long)|uniprotkb:Itm2b(gene name)|psi-mi:Itm2b(display_short)|uniprotkb:Immature BRI2(gene name synonym)|uniprotkb:Transmembrane protein BRI(gene name synonym)	psi-mi:eftu_rat(display_long)|uniprotkb:Tufm(gene name)|psi-mi:Tufm(display_short)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Martins et al. (2018)	imex:IM-28469|pubmed:29476059	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26440627|imex:IM-28469-5	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSRNOG00000016271(gene)|ensembl:ENSRNOT00000023037(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001540"(amyloid-beta binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0010008"(endosome membrane)|go:"GO:0030660"(Golgi-associated vesicle membrane)|go:"GO:0031301"(integral component of organelle membrane)|go:"GO:0042985"(negative regulation of amyloid precursor protein biosynthetic process)|interpro:IPR007084(BRICHOS)|interpro:IPR040145|mint:Q5XIE8|refseq:NP_001006964.1|rgd:620727	rgd:1305501|refseq:NP_001099765.1|ensembl:ENSRNOG00000018604(gene)|ensembl:ENSRNOT00000025203(transcript)|go:"GO:0003746"(translation elongation factor activity)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005739"(mitochondrion)|go:"GO:0006414"(translational elongation)|go:"GO:0042645"(mitochondrial nucleoid)|go:"GO:0045202"(synapse)|go:"GO:0045471"(response to ethanol)|go:"GO:0070125"(mitochondrial translational elongation)|interpro:IPR000795(Protein synthesis factor, GTP-binding)|interpro:IPR004160(Translation elongation factor EFTu/EF1A, C-terminal)|interpro:IPR004161(Translation elongation factor EFTu/EF1A, domain 2)|interpro:IPR004541(Translation elongation factor EFTu/EF1A, bacterial and organelle)|interpro:IPR009000(Translation elongation and initiation factors/Ribosomal, beta-barrel)|interpro:IPR009001(Translation elongation factor EF1A/initiation factor IF2gamma, C-terminal)|interpro:IPR027417|interpro:IPR031157|interpro:IPR033720|interpro:IPR041709|mint:P85834	-	-	-	figure legend:st1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10116(rat-hippocampus)|taxid:10116(Rattus norvegicus hippocampal neurons)	-	2020/10/30	2020/10/30	rogid:DtE+ZXAZKdCMvUW5K+jXQ5bH07M10116	rogid:7ijVJSb0XSiqlNjp70i4FXEF2z810116	rigid:zzsc1zNhBb5nwIRPeFpYOKgC3M8	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q5XIE8	uniprotkb:P05197	intact:EBI-15348306|ensembl:ENSRNOP00000023037	intact:EBI-915895|uniprotkb:P97619|ensembl:ENSRNOP00000041821	psi-mi:itm2b_rat(display_long)|uniprotkb:Itm2b(gene name)|psi-mi:Itm2b(display_short)|uniprotkb:Immature BRI2(gene name synonym)|uniprotkb:Transmembrane protein BRI(gene name synonym)	psi-mi:ef2_rat(display_long)|uniprotkb:Eef2(gene name)|psi-mi:Eef2(display_short)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Martins et al. (2018)	imex:IM-28469|pubmed:29476059	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26440627|imex:IM-28469-5	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSRNOG00000016271(gene)|ensembl:ENSRNOT00000023037(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001540"(amyloid-beta binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0010008"(endosome membrane)|go:"GO:0030660"(Golgi-associated vesicle membrane)|go:"GO:0031301"(integral component of organelle membrane)|go:"GO:0042985"(negative regulation of amyloid precursor protein biosynthetic process)|interpro:IPR007084(BRICHOS)|interpro:IPR040145|mint:Q5XIE8|refseq:NP_001006964.1|rgd:620727	rgd:61979|refseq:NP_058941.1|ensembl:ENSRNOG00000020266(gene)|ensembl:ENSRNOT00000047450(transcript)|go:"GO:0002039"(p53 binding)|go:"GO:0002244"(hematopoietic progenitor cell differentiation)|go:"GO:0002931"(response to ischemia)|go:"GO:0003009"(skeletal muscle contraction)|go:"GO:0003723"(RNA binding)|go:"GO:0003746"(translation elongation factor activity)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005844"(polysome)|go:"GO:0005886"(plasma membrane)|go:"GO:0006414"(translational elongation)|go:"GO:0007568"(aging)|go:"GO:0008097"(5S rRNA binding)|go:"GO:0014009"(glial cell proliferation)|go:"GO:0016235"(aggresome)|go:"GO:0019901"(protein kinase binding)|go:"GO:0032355"(response to estradiol)|go:"GO:0034976"(response to endoplasmic reticulum stress)|go:"GO:0035914"(skeletal muscle cell differentiation)|go:"GO:0042493"|go:"GO:0042542"(response to hydrogen peroxide)|go:"GO:0042788"(polysomal ribosome)|go:"GO:0043022"(ribosome binding)|go:"GO:0045121"(membrane raft)|go:"GO:0045202"(synapse)|go:"GO:0045471"(response to ethanol)|go:"GO:0045727"(positive regulation of translation)|go:"GO:0051015"(actin filament binding)|go:"GO:0051593"(response to folic acid)|go:"GO:1990416"(cellular response to brain-derived neurotrophic factor stimulus)|go:"GO:1990904"(ribonucleoprotein complex)|go:"GO:2000767"(positive regulation of cytoplasmic translation)|interpro:IPR000640(Translation elongation factor EFG/EF2, C-terminal)|interpro:IPR000795(Protein synthesis factor, GTP-binding)|interpro:IPR004161(Translation elongation factor EFTu/EF1A, domain 2)|interpro:IPR005225(Small GTP-binding protein)|interpro:IPR005517(Translation elongation factor EFG/EF2, domain IV)|interpro:IPR009000(Translation elongation and initiation factors/Ribosomal, beta-barrel)|interpro:IPR014721(Ribosomal protein S5 domain 2-type fold)|interpro:IPR020568|interpro:IPR027417|interpro:IPR031157|interpro:IPR035647|interpro:IPR041095|mint:P05197|reactome:R-RNO-156902|reactome:R-RNO-5358493|reactome:R-RNO-6798695	-	-	-	figure legend:st1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10116(rat-hippocampus)|taxid:10116(Rattus norvegicus hippocampal neurons)	-	2020/10/30	2020/10/30	rogid:DtE+ZXAZKdCMvUW5K+jXQ5bH07M10116	rogid:JpTfRnV5VR9V+mR+c5hxYJ0FsM410116	rigid:zzsc1zNhBb5nwIRPeFpYOKgC3M8	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q5XIE8	uniprotkb:P31016	intact:EBI-15348306|ensembl:ENSRNOP00000023037	intact:EBI-375655|uniprotkb:P97631|ensembl:ENSRNOP00000059045	psi-mi:itm2b_rat(display_long)|uniprotkb:Itm2b(gene name)|psi-mi:Itm2b(display_short)|uniprotkb:Immature BRI2(gene name synonym)|uniprotkb:Transmembrane protein BRI(gene name synonym)	psi-mi:dlg4_rat(display_long)|uniprotkb:Dlg4(gene name)|psi-mi:Dlg4(display_short)|uniprotkb:Dlgh4(gene name synonym)|uniprotkb:Postsynaptic density protein 95(gene name synonym)|uniprotkb:Synapse-associated protein 90(gene name synonym)|uniprotkb:Psd95(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Martins et al. (2018)	imex:IM-28469|pubmed:29476059	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26440627|imex:IM-28469-5	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSRNOG00000016271(gene)|ensembl:ENSRNOT00000023037(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001540"(amyloid-beta binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0010008"(endosome membrane)|go:"GO:0030660"(Golgi-associated vesicle membrane)|go:"GO:0031301"(integral component of organelle membrane)|go:"GO:0042985"(negative regulation of amyloid precursor protein biosynthetic process)|interpro:IPR007084(BRICHOS)|interpro:IPR040145|mint:Q5XIE8|refseq:NP_001006964.1|rgd:620727	go:"GO:0030165"(PDZ domain binding)|go:"GO:0030425"(dendrite)|go:"GO:0030863"(cortical cytoskeleton)|go:"GO:0031234"(extrinsic component of cytoplasmic side of plasma membrane)|go:"GO:0031594"(neuromuscular junction)|go:"GO:0031697"(beta-1 adrenergic receptor binding)|go:"GO:0031698"(beta-2 adrenergic receptor binding)|go:"GO:0031748"(D1 dopamine receptor binding)|go:"GO:0031812"(P2Y1 nucleotide receptor binding)|go:"GO:0032281"(AMPA glutamate receptor complex)|go:"GO:0032839"(dendrite cytoplasm)|go:"GO:0033130"(acetylcholine receptor binding)|go:"GO:0035176"(social behavior)|go:"GO:0035254"(glutamate receptor binding)|go:"GO:0035255"(ionotropic glutamate receptor binding)|go:"GO:0035418"(protein localization to synapse)|go:"GO:0035641"(locomotory exploration behavior)|go:"GO:0035865"(cellular response to potassium ion)|go:"GO:0043005"(neuron projection)|go:"GO:0043113"(receptor clustering)|go:"GO:0043197"(dendritic spine)|go:"GO:0044224"(juxtaparanode region of axon)|go:"GO:0044300"(cerebellar mossy fiber)|go:"GO:0044306"(neuron projection terminus)|go:"GO:0044309"(neuron spine)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045161"(neuronal ion channel clustering)|go:"GO:0045184"(establishment of protein localization)|go:"GO:0045202"(synapse)|go:"GO:0045211"(postsynaptic membrane)|go:"GO:0048168"(regulation of neuronal synaptic plasticity)|go:"GO:0048169"(regulation of long-term neuronal synaptic plasticity)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0050806"(positive regulation of synaptic transmission)|go:"GO:0050885"(neuromuscular process controlling balance)|go:"GO:0060076"(excitatory synapse)|go:"GO:0060997"(dendritic spine morphogenesis)|go:"GO:0061098"(positive regulation of protein tyrosine kinase activity)|go:"GO:0099031"(anchored component of postsynaptic density membrane)|go:"GO:0065003"(protein-containing complex assembly)|go:"GO:0071625"(vocalization behavior)|go:"GO:0071944"(cell periphery)|go:"GO:0097060"(synaptic membrane)|go:"GO:0097061"(dendritic spine organization)|go:"GO:0097109"(neuroligin family protein binding)|go:"GO:0099645"(neurotransmitter receptor localization to postsynaptic specialization membrane)|go:"GO:0150012"(positive regulation of neuron projection arborization)|go:"GO:0097110"(scaffold protein binding)|go:"GO:1904719"(positive regulation of AMPA glutamate receptor clustering)|go:"GO:0097113"(AMPA glutamate receptor clustering)|go:"GO:0097120"(receptor localization to synapse)|go:"GO:0098609"(cell-cell adhesion)|go:"GO:0098794"(postsynapse)|go:"GO:0098839"(postsynaptic density membrane)|go:"GO:0098919"(structural constituent of postsynaptic density)|go:"GO:0098970"(postsynaptic neurotransmitter receptor diffusion trapping)|go:"GO:2000310"(regulation of NMDA receptor activity)|go:"GO:2000463"(positive regulation of excitatory postsynaptic potential)|go:"GO:2000821"(regulation of grooming behavior)|interpro:IPR001452(Src homology-3)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR008144(Guanylate kinase)|interpro:IPR008145(Guanylate kinase/L-type calcium channel region)|rcsb pdb:1TP3|interpro:IPR016313("Membrane-associated guanylate kinase (MAGUK) scaffold protein")|interpro:IPR019583|interpro:IPR019590|interpro:IPR020590|interpro:IPR027417|interpro:IPR036028|interpro:IPR036034|mint:P31016|rcsb pdb:1BE9|rcsb pdb:1BFE|rcsb pdb:1IU0|rcsb pdb:1IU2|rcsb pdb:1JXM|rcsb pdb:1JXO|rcsb pdb:1KJW|rcsb pdb:1QLC|rcsb pdb:1RGR|rcsb pdb:5MZ7|rcsb pdb:5W72|rcsb pdb:5YPO|rcsb pdb:5YPR|rcsb pdb:7CQF|reactome:R-RNO-399719|reactome:R-RNO-438066|reactome:R-RNO-451308|reactome:R-RNO-5625900|reactome:R-RNO-5673001|reactome:R-RNO-5682910|reactome:R-RNO-6794361|reactome:R-RNO-8849932|rcsb pdb:1TP5|rcsb pdb:1TQ3|rcsb pdb:2KA9|rcsb pdb:2MHO|rcsb pdb:2XKX|rcsb pdb:3GSL|rcsb pdb:3WP0|rcsb pdb:3WP1|rcsb pdb:5B64|rcsb pdb:5D13|rcsb pdb:5GNV|rcsb pdb:5HDY|rcsb pdb:5HEB|rcsb pdb:5HED|rcsb pdb:5HET|rcsb pdb:5HEY|rcsb pdb:5HF1|rcsb pdb:5HF4|rcsb pdb:5HFB|rcsb pdb:5HFC|rcsb pdb:5HFD|rcsb pdb:5HFE|rcsb pdb:5HFF|ensembl:ENSRNOG00000018526(gene)|ensembl:ENSRNOT00000068493(transcript)|go:"GO:0002091"(negative regulation of receptor internalization)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005109"(frizzled binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0007204"(positive regulation of cytosolic calcium ion concentration)|go:"GO:0007268"(chemical synaptic transmission)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008328"(ionotropic glutamate receptor complex)|go:"GO:0014069"(postsynaptic density)|go:"GO:0016020"(membrane)|go:"GO:0016188"(synaptic vesicle maturation)|go:"GO:0019865"(immunoglobulin binding)|go:"GO:0019894"(kinesin binding)|go:"GO:0019900"(kinase binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0019903"(protein phosphatase binding)|go:"GO:0030054"(cell junction)|rgd:68424|refseq:NP_062567.1|dip:DIP-29264N	-	-	-	figure legend:st1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10116(rat-hippocampus)|taxid:10116(Rattus norvegicus hippocampal neurons)	-	2020/10/30	2020/10/30	rogid:DtE+ZXAZKdCMvUW5K+jXQ5bH07M10116	rogid:4oWbxT/HVvWQqdbFqt3htRuQNpw10116	rigid:zzsc1zNhBb5nwIRPeFpYOKgC3M8	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q5XIE8	uniprotkb:P25809	intact:EBI-15348306|ensembl:ENSRNOP00000023037	intact:EBI-2255977	psi-mi:itm2b_rat(display_long)|uniprotkb:Itm2b(gene name)|psi-mi:Itm2b(display_short)|uniprotkb:Immature BRI2(gene name synonym)|uniprotkb:Transmembrane protein BRI(gene name synonym)	psi-mi:kcru_rat(display_long)|uniprotkb:Ckmt1(gene name)|psi-mi:Ckmt1(display_short)|uniprotkb:Ckmt(gene name synonym)|uniprotkb:Ubiquitous mitochondrial creatine kinase(gene name synonym)|uniprotkb:Acidic-type mitochondrial creatine kinase(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Martins et al. (2018)	imex:IM-28469|pubmed:29476059	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26440627|imex:IM-28469-5	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSRNOG00000016271(gene)|ensembl:ENSRNOT00000023037(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001540"(amyloid-beta binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0010008"(endosome membrane)|go:"GO:0030660"(Golgi-associated vesicle membrane)|go:"GO:0031301"(integral component of organelle membrane)|go:"GO:0042985"(negative regulation of amyloid precursor protein biosynthetic process)|interpro:IPR007084(BRICHOS)|interpro:IPR040145|mint:Q5XIE8|refseq:NP_001006964.1|rgd:620727	rgd:61976|interpro:IPR022415|interpro:IPR022414|interpro:IPR022413|interpro:IPR014746(Glutamine synthetase/guanido kinase, catalytic region)|interpro:IPR000749("ATP:guanido phosphotransferase")|mint:P25809|interpro:IPR036802|go:"GO:0001822"(kidney development)|go:"GO:0004111"(creatine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0007420"(brain development)|go:"GO:0007519"(skeletal muscle tissue development)|go:"GO:0016301"(kinase activity)|go:"GO:0021549"(cerebellum development)|go:"GO:0032091"(negative regulation of protein binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043204"(perikaryon)|go:"GO:0044289"(mitochondrial inner-outer membrane contact site)|go:"GO:0046314"(phosphocreatine biosynthetic process)|go:"GO:0048565"(digestive tract development)|reactome:R-RNO-71288	-	-	-	figure legend:st1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10116(rat-hippocampus)|taxid:10116(Rattus norvegicus hippocampal neurons)	-	2020/10/30	2020/10/30	rogid:DtE+ZXAZKdCMvUW5K+jXQ5bH07M10116	rogid:P0XRQOCYb/CdvJW7dt9XOvxDJ4Y10116	rigid:zzsc1zNhBb5nwIRPeFpYOKgC3M8	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q5XIE8	uniprotkb:P31721	intact:EBI-15348306|ensembl:ENSRNOP00000023037	intact:EBI-26437724	psi-mi:itm2b_rat(display_long)|uniprotkb:Itm2b(gene name)|psi-mi:Itm2b(display_short)|uniprotkb:Immature BRI2(gene name synonym)|uniprotkb:Transmembrane protein BRI(gene name synonym)	psi-mi:c1qb_rat(display_long)|uniprotkb:C1qb(gene name)|psi-mi:C1qb(display_short)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Martins et al. (2018)	imex:IM-28469|pubmed:29476059	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26440627|imex:IM-28469-5	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSRNOG00000016271(gene)|ensembl:ENSRNOT00000023037(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001540"(amyloid-beta binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0010008"(endosome membrane)|go:"GO:0030660"(Golgi-associated vesicle membrane)|go:"GO:0031301"(integral component of organelle membrane)|go:"GO:0042985"(negative regulation of amyloid precursor protein biosynthetic process)|interpro:IPR007084(BRICHOS)|interpro:IPR040145|mint:Q5XIE8|refseq:NP_001006964.1|rgd:620727	go:"GO:0005581"(collagen trimer)|go:"GO:0005602"(complement component C1 complex)|go:"GO:0006955"(immune response)|go:"GO:0006958"(complement activation, classical pathway)|go:"GO:0007420"(brain development)|go:"GO:0007568"(aging)|go:"GO:0010033"(response to organic substance)|go:"GO:0042802"(identical protein binding)|go:"GO:0045087"(innate immune response)|go:"GO:0045202"(synapse)|go:"GO:0048839"(inner ear development)|go:"GO:0051384"(response to glucocorticoid)|go:"GO:0098794"(postsynapse)|go:"GO:0098883"(synapse pruning)|reactome:R-RNO-166663|reactome:R-RNO-173623|reactome:R-RNO-977606|mint:P31721|refseq:NP_062135.1|interpro:IPR001073(Complement C1q protein)|interpro:IPR008160(Collagen triple helix repeat)|interpro:IPR037573|interpro:IPR008983(Tumour necrosis factor-like)|rgd:2229	-	-	-	figure legend:st1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10116(rat-hippocampus)|taxid:10116(Rattus norvegicus hippocampal neurons)	-	2020/10/30	2020/10/30	rogid:DtE+ZXAZKdCMvUW5K+jXQ5bH07M10116	rogid:2+DKSXCWFTd8r4uTtwJf8hdJqMQ10116	rigid:zzsc1zNhBb5nwIRPeFpYOKgC3M8	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q5XIE8	uniprotkb:P45592	intact:EBI-15348306|ensembl:ENSRNOP00000023037	intact:EBI-917556|ensembl:ENSRNOP00000059624	psi-mi:itm2b_rat(display_long)|uniprotkb:Itm2b(gene name)|psi-mi:Itm2b(display_short)|uniprotkb:Immature BRI2(gene name synonym)|uniprotkb:Transmembrane protein BRI(gene name synonym)	psi-mi:cof1_rat(display_long)|uniprotkb:Cofilin, non-muscle isoform(gene name synonym)|uniprotkb:Cfl1(gene name)|psi-mi:Cfl1(display_short)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Martins et al. (2018)	imex:IM-28469|pubmed:29476059	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26440627|imex:IM-28469-5	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSRNOG00000016271(gene)|ensembl:ENSRNOT00000023037(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001540"(amyloid-beta binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0010008"(endosome membrane)|go:"GO:0030660"(Golgi-associated vesicle membrane)|go:"GO:0031301"(integral component of organelle membrane)|go:"GO:0042985"(negative regulation of amyloid precursor protein biosynthetic process)|interpro:IPR007084(BRICHOS)|interpro:IPR040145|mint:Q5XIE8|refseq:NP_001006964.1|rgd:620727	rgd:69285|refseq:NP_058843.1|ensembl:ENSRNOG00000020660(gene)|ensembl:ENSRNOT00000015962(transcript)|go:"GO:0000281"(mitotic cytokinesis)|go:"GO:0001755"(neural crest cell migration)|go:"GO:0001842"(neural fold formation)|go:"GO:0003779"(actin binding)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005925"(focal adhesion)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0007010"(cytoskeleton organization)|go:"GO:0007015"(actin filament organization)|go:"GO:0007162"(negative regulation of cell adhesion)|go:"GO:0009615"(response to virus)|go:"GO:0010592"(positive regulation of lamellipodium assembly)|go:"GO:0010593"(negative regulation of lamellipodium assembly)|go:"GO:0014070"(response to organic cyclic compound)|go:"GO:0014823"(response to activity)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0016363"(nuclear matrix)|go:"GO:0019903"(protein phosphatase binding)|go:"GO:0021766"(hippocampus development)|go:"GO:0022604"(regulation of cell morphogenesis)|go:"GO:0030010"(establishment of cell polarity)|go:"GO:0030027"(lamellipodium)|go:"GO:0030030"(cell projection organization)|go:"GO:0030042"(actin filament depolymerization)|go:"GO:0030043"(actin filament fragmentation)|go:"GO:0030175"(filopodium)|go:"GO:0030307"(positive regulation of cell growth)|go:"GO:0030426"(growth cone)|go:"GO:0030835"(negative regulation of actin filament depolymerization)|go:"GO:0030836"(positive regulation of actin filament depolymerization)|go:"GO:0030864"(cortical actin cytoskeleton)|go:"GO:0031252"(cell leading edge)|go:"GO:0031258"(lamellipodium membrane)|go:"GO:0031915"(positive regulation of synaptic plasticity)|go:"GO:0031966"(mitochondrial membrane)|go:"GO:0032232"(negative regulation of actin filament bundle assembly)|go:"GO:0032587"(ruffle membrane)|go:"GO:0040019"(positive regulation of embryonic development)|go:"GO:0043005"(neuron projection)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043197"(dendritic spine)|go:"GO:0043200"(response to amino acid)|go:"GO:0044794"(positive regulation by host of viral process)|go:"GO:0045792"(negative regulation of cell size)|go:"GO:0045862"(positive regulation of proteolysis)|go:"GO:0048870"(cell motility)|go:"GO:0051014"(actin filament severing)|go:"GO:0051015"(actin filament binding)|go:"GO:0051293"(establishment of spindle localization)|go:"GO:0051511"(negative regulation of unidimensional cell growth)|go:"GO:0051894"(positive regulation of focal adhesion assembly)|go:"GO:0060999"(positive regulation of dendritic spine development)|go:"GO:0061001"(regulation of dendritic spine morphogenesis)|go:"GO:0070301"(cellular response to hydrogen peroxide)|go:"GO:0071347"(cellular response to interleukin-1)|go:"GO:0071354"(cellular response to interleukin-6)|go:"GO:0071356"(cellular response to tumor necrosis factor)|go:"GO:0071362"(cellular response to ether)|go:"GO:0071364"(cellular response to epidermal growth factor stimulus)|go:"GO:0090732"(cofilin-actin rod)|go:"GO:0097060"(synaptic membrane)|go:"GO:0098885"(modification of postsynaptic actin cytoskeleton)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:1902936"(phosphatidylinositol bisphosphate binding)|go:"GO:1902951"(negative regulation of dendritic spine maintenance)|go:"GO:1904783"(positive regulation of NMDA glutamate receptor activity)|go:"GO:1905873"(positive regulation of protein localization to cell leading edge)|go:"GO:1905875"(negative regulation of postsynaptic density organization)|go:"GO:1990314"(cellular response to insulin-like growth factor stimulus)|go:"GO:2000146"(negative regulation of cell motility)|go:"GO:2000147"(positive regulation of cell motility)|go:"GO:2000784"(positive regulation of establishment of cell polarity regulating cell shape)|go:"GO:2000814"(positive regulation of barbed-end actin filament capping)|interpro:IPR002108(Actin-binding, cofilin/tropomyosin type)|interpro:IPR017904|interpro:IPR027234|interpro:IPR029006|mint:P45592	-	-	-	figure legend:st1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10116(rat-hippocampus)|taxid:10116(Rattus norvegicus hippocampal neurons)	-	2020/10/30	2020/10/30	rogid:DtE+ZXAZKdCMvUW5K+jXQ5bH07M10116	rogid:xwFEqVHm0stGEHpMoijBFH/LwPY10116	rigid:zzsc1zNhBb5nwIRPeFpYOKgC3M8	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q5XIE8	uniprotkb:P40241	intact:EBI-15348306|ensembl:ENSRNOP00000023037	intact:EBI-26437684|ensembl:ENSRNOP00000026633	psi-mi:itm2b_rat(display_long)|uniprotkb:Itm2b(gene name)|psi-mi:Itm2b(display_short)|uniprotkb:Immature BRI2(gene name synonym)|uniprotkb:Transmembrane protein BRI(gene name synonym)	psi-mi:cd9_rat(display_long)|uniprotkb:Cd9(gene name)|psi-mi:Cd9(display_short)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Martins et al. (2018)	imex:IM-28469|pubmed:29476059	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26440627|imex:IM-28469-5	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSRNOG00000016271(gene)|ensembl:ENSRNOT00000023037(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001540"(amyloid-beta binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0010008"(endosome membrane)|go:"GO:0030660"(Golgi-associated vesicle membrane)|go:"GO:0031301"(integral component of organelle membrane)|go:"GO:0042985"(negative regulation of amyloid precursor protein biosynthetic process)|interpro:IPR007084(BRICHOS)|interpro:IPR040145|mint:Q5XIE8|refseq:NP_001006964.1|rgd:620727	reactome:R-RNO-1300645|ensembl:ENSRNOG00000019556(gene)|ensembl:ENSRNOT00000026633(transcript)|go:"GO:0005178"(integrin binding)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0007338"(single fertilization)|go:"GO:0007342"(fusion of sperm to egg plasma membrane involved in single fertilization)|go:"GO:0007420"(brain development)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0008347"(glial cell migration)|go:"GO:0009414"(response to water deprivation)|go:"GO:0009897"(external side of plasma membrane)|go:"GO:0009986"(cell surface)|go:"GO:0014003"(oligodendrocyte development)|go:"GO:0014905"(myoblast fusion involved in skeletal muscle regeneration)|go:"GO:0016020"(membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0030913"(paranodal junction assembly)|go:"GO:0031623"(receptor internalization)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035036"(sperm-egg recognition)|go:"GO:0051271"(negative regulation of cellular component movement)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071404"(cellular response to low-density lipoprotein particle stimulus)|go:"GO:0090331"(negative regulation of platelet aggregation)|go:"GO:1905521"(regulation of macrophage migration)|interpro:IPR000301(CD9/CD37/CD63 antigen)|interpro:IPR008952(Tetraspanin)|interpro:IPR018499|interpro:IPR018503|interpro:IPR042055|mint:P40241|reactome:R-RNO-114608|go:"GO:0007155"(cell adhesion)|refseq:NP_444177.1|rgd:2318	-	-	-	figure legend:st1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10116(rat-hippocampus)|taxid:10116(Rattus norvegicus hippocampal neurons)	-	2020/10/30	2020/10/30	rogid:DtE+ZXAZKdCMvUW5K+jXQ5bH07M10116	rogid:UagE7Mr3lqoy8A7VYuUSd+UezKc10116	rigid:zzsc1zNhBb5nwIRPeFpYOKgC3M8	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q5XIE8	uniprotkb:P19139	intact:EBI-15348306|ensembl:ENSRNOP00000023037	intact:EBI-1373494|uniprotkb:Q5BKC1|ensembl:ENSRNOP00000007558	psi-mi:itm2b_rat(display_long)|uniprotkb:Itm2b(gene name)|psi-mi:Itm2b(display_short)|uniprotkb:Immature BRI2(gene name synonym)|uniprotkb:Transmembrane protein BRI(gene name synonym)	psi-mi:csk21_rat(display_long)|uniprotkb:Csnk2a1(gene name)|psi-mi:Csnk2a1(display_short)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Martins et al. (2018)	imex:IM-28469|pubmed:29476059	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26440627|imex:IM-28469-5	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSRNOG00000016271(gene)|ensembl:ENSRNOT00000023037(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001540"(amyloid-beta binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0010008"(endosome membrane)|go:"GO:0030660"(Golgi-associated vesicle membrane)|go:"GO:0031301"(integral component of organelle membrane)|go:"GO:0042985"(negative regulation of amyloid precursor protein biosynthetic process)|interpro:IPR007084(BRICHOS)|interpro:IPR040145|mint:Q5XIE8|refseq:NP_001006964.1|rgd:620727	rgd:621663|refseq:NP_446276.1|refseq:XP_006235282.1|refseq:XP_006235283.1|reactome:R-RNO-6804756|reactome:R-RNO-6814122|reactome:R-RNO-8934903|reactome:R-RNO-8939243|reactome:R-RNO-8948751|ensembl:ENSRNOG00000005276(gene)|ensembl:ENSRNOT00000007558(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005956"(protein kinase CK2 complex)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0006915"(apoptotic process)|go:"GO:0007049"(cell cycle)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0016301"(kinase activity)|go:"GO:0016580"(Sin3 complex)|go:"GO:0016581"(NuRD complex)|go:"GO:0018105"(peptidyl-serine phosphorylation)|go:"GO:0018107"(peptidyl-threonine phosphorylation)|go:"GO:0019888"(protein phosphatase regulator activity)|go:"GO:0021987"(cerebral cortex development)|go:"GO:0030177"(positive regulation of Wnt signaling pathway)|go:"GO:0030307"(positive regulation of cell growth)|go:"GO:0033574"(response to testosterone)|go:"GO:0042802"(identical protein binding)|go:"GO:0043021"(ribonucleoprotein complex binding)|go:"GO:0043154"(negative regulation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0045732"(positive regulation of protein catabolic process)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0047485"(protein N-terminus binding)|go:"GO:0048511"(rhythmic process)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0097421"(liver regeneration)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:1903076"(regulation of protein localization to plasma membrane)|go:"GO:1905818"(regulation of chromosome separation)|go:"GO:2000059"(negative regulation of ubiquitin-dependent protein catabolic process)|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|mint:P19139|rcsb pdb:2R7I|reactome:R-RNO-1483191|reactome:R-RNO-201688|reactome:R-RNO-2514853|reactome:R-RNO-445144	-	-	-	figure legend:st1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10116(rat-hippocampus)|taxid:10116(Rattus norvegicus hippocampal neurons)	-	2020/10/30	2020/10/30	rogid:DtE+ZXAZKdCMvUW5K+jXQ5bH07M10116	rogid:igJEbVxBh30nMZF6jfiISzpHEMQ10116	rigid:zzsc1zNhBb5nwIRPeFpYOKgC3M8	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q5XIE8	uniprotkb:Q9ESS6	intact:EBI-15348306|ensembl:ENSRNOP00000023037	intact:EBI-26437661|ensembl:ENSRNOP00000047809	psi-mi:itm2b_rat(display_long)|uniprotkb:Itm2b(gene name)|psi-mi:Itm2b(display_short)|uniprotkb:Immature BRI2(gene name synonym)|uniprotkb:Transmembrane protein BRI(gene name synonym)	psi-mi:bcam_rat(display_long)|uniprotkb:Bcam(gene name)|psi-mi:Bcam(display_short)|uniprotkb:Lu(gene name synonym)|uniprotkb:B-CAM cell surface glycoprotein(gene name synonym)|uniprotkb:Lutheran antigen(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Martins et al. (2018)	imex:IM-28469|pubmed:29476059	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26440627|imex:IM-28469-5	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSRNOG00000016271(gene)|ensembl:ENSRNOT00000023037(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001540"(amyloid-beta binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0010008"(endosome membrane)|go:"GO:0030660"(Golgi-associated vesicle membrane)|go:"GO:0031301"(integral component of organelle membrane)|go:"GO:0042985"(negative regulation of amyloid precursor protein biosynthetic process)|interpro:IPR007084(BRICHOS)|interpro:IPR040145|mint:Q5XIE8|refseq:NP_001006964.1|rgd:620727	ensembl:ENSRNOG00000029399(gene)|ensembl:ENSRNOT00000045574(transcript)|go:"GO:0005055"(laminin receptor activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0007155"(cell adhesion)|go:"GO:0007160"(cell-matrix adhesion)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0009986"(cell surface)|go:"GO:0016021"(integral component of membrane)|go:"GO:0043236"(laminin binding)|interpro:IPR003598(Immunoglobulin subtype 2)|interpro:IPR003599(Immunoglobulin subtype)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR013162(CD80-like, immunoglobulin C2-set)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR036179|mint:Q9ESS6|refseq:NP_113940.1|rgd:68378	-	-	-	figure legend:st1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10116(rat-hippocampus)|taxid:10116(Rattus norvegicus hippocampal neurons)	-	2020/10/30	2020/10/30	rogid:DtE+ZXAZKdCMvUW5K+jXQ5bH07M10116	rogid:gXifukdZ+aemcGCwqz/Q8qlsqBo10116	rigid:zzsc1zNhBb5nwIRPeFpYOKgC3M8	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q5XIE8	uniprotkb:Q9WTP0	intact:EBI-15348306|ensembl:ENSRNOP00000023037	intact:EBI-11169976|uniprotkb:Q9WTP1	psi-mi:itm2b_rat(display_long)|uniprotkb:Itm2b(gene name)|psi-mi:Itm2b(display_short)|uniprotkb:Immature BRI2(gene name synonym)|uniprotkb:Transmembrane protein BRI(gene name synonym)	psi-mi:e41l1_rat(display_long)|uniprotkb:Epb41l1(gene name)|psi-mi:Epb41l1(display_short)|uniprotkb:Epb4.1l1(gene name synonym)|uniprotkb:Neuronal protein 4.1(gene name synonym)|uniprotkb:Erythrocyte membrane protein band 4.1-like 1(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Martins et al. (2018)	imex:IM-28469|pubmed:29476059	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26440627|imex:IM-28469-5	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSRNOG00000016271(gene)|ensembl:ENSRNOT00000023037(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001540"(amyloid-beta binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0010008"(endosome membrane)|go:"GO:0030660"(Golgi-associated vesicle membrane)|go:"GO:0031301"(integral component of organelle membrane)|go:"GO:0042985"(negative regulation of amyloid precursor protein biosynthetic process)|interpro:IPR007084(BRICHOS)|interpro:IPR040145|mint:Q5XIE8|refseq:NP_001006964.1|rgd:620727	refseq:NP_742087.1|interpro:IPR008379(Band 4.1, C-terminal)|interpro:IPR019749|interpro:IPR000798(Ezrin/radixin/moesin ERM)|interpro:IPR014847("FERM adjacent (FA)")|interpro:IPR014352(FERM/acyl-CoA-binding protein, 3-helical bundle)|interpro:IPR019748|interpro:IPR019747|interpro:IPR000299(Band 4.1, N-terminal)|interpro:IPR018979|interpro:IPR018980|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR007477(SAB)|interpro:IPR029071|rgd:71087|go:"GO:0003779"(actin binding)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005886"(plasma membrane)|go:"GO:0014069"(postsynaptic density)|go:"GO:0030866"(cortical actin cytoskeleton organization)|go:"GO:0031032"(actomyosin structure organization)|go:"GO:0032991"(protein-containing complex)|go:"GO:0097060"(synaptic membrane)|reactome:R-RNO-399719|reactome:R-RNO-6794361|mint:Q9WTP0|interpro:IPR035963	-	-	-	figure legend:st1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10116(rat-hippocampus)|taxid:10116(Rattus norvegicus hippocampal neurons)	-	2020/10/30	2020/10/30	rogid:DtE+ZXAZKdCMvUW5K+jXQ5bH07M10116	rogid:UEt+cCxW/3aDNyIqQUHiCHjI4K410116	rigid:zzsc1zNhBb5nwIRPeFpYOKgC3M8	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q5XIE8	uniprotkb:Q06647	intact:EBI-15348306|ensembl:ENSRNOP00000023037	intact:EBI-918179|ensembl:ENSRNOP00000002732	psi-mi:itm2b_rat(display_long)|uniprotkb:Itm2b(gene name)|psi-mi:Itm2b(display_short)|uniprotkb:Immature BRI2(gene name synonym)|uniprotkb:Transmembrane protein BRI(gene name synonym)	psi-mi:atpo_rat(display_long)|uniprotkb:Atp5po(gene name)|psi-mi:Atp5po(display_short)|uniprotkb:ATP synthase peripheral stalk subunit OSCP(gene name synonym)|uniprotkb:Atp5o(gene name synonym)|uniprotkb:Oligomycin sensitivity conferral protein(gene name synonym)|uniprotkb:Sperm flagella protein 4(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Martins et al. (2018)	imex:IM-28469|pubmed:29476059	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26440627|imex:IM-28469-5	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSRNOG00000016271(gene)|ensembl:ENSRNOT00000023037(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001540"(amyloid-beta binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0010008"(endosome membrane)|go:"GO:0030660"(Golgi-associated vesicle membrane)|go:"GO:0031301"(integral component of organelle membrane)|go:"GO:0042985"(negative regulation of amyloid precursor protein biosynthetic process)|interpro:IPR007084(BRICHOS)|interpro:IPR040145|mint:Q5XIE8|refseq:NP_001006964.1|rgd:620727	rgd:621379|refseq:NP_620238.1|ensembl:ENSRNOG00000001991(gene)|ensembl:ENSRNOT00000002732(transcript)|go:"GO:0000274"(mitochondrial proton-transporting ATP synthase, stator stalk)|go:"GO:0000276"("mitochondrial proton-transporting ATP synthase complex, coupling factor F(o)")|go:"GO:0005739"(mitochondrion)|go:"GO:0005753"(mitochondrial proton-transporting ATP synthase complex)|go:"GO:0005886"(plasma membrane)|go:"GO:0006754"(ATP biosynthetic process)|go:"GO:0009986"(cell surface)|go:"GO:0015986"(ATP synthesis coupled proton transport)|go:"GO:0042776"(mitochondrial ATP synthesis coupled proton transport)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045261"("proton-transporting ATP synthase complex, catalytic core F(1)")|go:"GO:0046034"(ATP metabolic process)|go:"GO:0046933"(proton-transporting ATP synthase activity, rotational mechanism)|go:"GO:0071320"(cellular response to cAMP)|go:"GO:0071345"(cellular response to cytokine stimulus)|go:"GO:1903924"(estradiol binding)|interpro:IPR000711(ATPase, F1 complex, OSCP/delta subunit)|interpro:IPR020781|interpro:IPR026015|mint:Q06647|reactome:R-RNO-163210|reactome:R-RNO-8949613	-	-	-	figure legend:st1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10116(rat-hippocampus)|taxid:10116(Rattus norvegicus hippocampal neurons)	-	2020/10/30	2020/10/30	rogid:DtE+ZXAZKdCMvUW5K+jXQ5bH07M10116	rogid:F/PihaxUf1uclL8LOwKpSse+dCA10116	rigid:zzsc1zNhBb5nwIRPeFpYOKgC3M8	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q5XIE8	uniprotkb:P35435	intact:EBI-15348306|ensembl:ENSRNOP00000023037	intact:EBI-917355	psi-mi:itm2b_rat(display_long)|uniprotkb:Itm2b(gene name)|psi-mi:Itm2b(display_short)|uniprotkb:Immature BRI2(gene name synonym)|uniprotkb:Transmembrane protein BRI(gene name synonym)	psi-mi:atpg_rat(display_long)|uniprotkb:Atp5f1c(gene name)|psi-mi:Atp5f1c(display_short)|uniprotkb:ATP synthase F1 subunit gamma(gene name synonym)|uniprotkb:Atp5c(gene name synonym)|uniprotkb:Atp5c1(gene name synonym)|uniprotkb:F-ATPase gamma subunit(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Martins et al. (2018)	imex:IM-28469|pubmed:29476059	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26440627|imex:IM-28469-5	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSRNOG00000016271(gene)|ensembl:ENSRNOT00000023037(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001540"(amyloid-beta binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0010008"(endosome membrane)|go:"GO:0030660"(Golgi-associated vesicle membrane)|go:"GO:0031301"(integral component of organelle membrane)|go:"GO:0042985"(negative regulation of amyloid precursor protein biosynthetic process)|interpro:IPR007084(BRICHOS)|interpro:IPR040145|mint:Q5XIE8|refseq:NP_001006964.1|rgd:620727	rgd:620011|interpro:IPR000131(ATPase, F1 complex, gamma subunit)|interpro:IPR023632|mint:P35435|interpro:IPR035968|go:"GO:0000275"("mitochondrial proton-transporting ATP synthase complex, catalytic sector F(1)")|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005753"(mitochondrial proton-transporting ATP synthase complex)|go:"GO:0015986"(ATP synthesis coupled proton transport)|go:"GO:0042776"(mitochondrial ATP synthesis coupled proton transport)|go:"GO:0045261"("proton-transporting ATP synthase complex, catalytic core F(1)")|go:"GO:0046034"(ATP metabolic process)|go:"GO:0046933"(proton-transporting ATP synthase activity, rotational mechanism)|go:"GO:0071732"(cellular response to nitric oxide)|rcsb pdb:1MAB|rcsb pdb:2F43|reactome:R-RNO-163210|reactome:R-RNO-8949613	-	-	-	figure legend:st1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10116(rat-hippocampus)|taxid:10116(Rattus norvegicus hippocampal neurons)	-	2020/10/30	2020/10/30	rogid:DtE+ZXAZKdCMvUW5K+jXQ5bH07M10116	rogid:py9RCXV2/aoMy8UslZteKeJAdak10116	rigid:zzsc1zNhBb5nwIRPeFpYOKgC3M8	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q5XIE8	uniprotkb:P18484	intact:EBI-15348306|ensembl:ENSRNOP00000023037	intact:EBI-539360	psi-mi:itm2b_rat(display_long)|uniprotkb:Itm2b(gene name)|psi-mi:Itm2b(display_short)|uniprotkb:Immature BRI2(gene name synonym)|uniprotkb:Transmembrane protein BRI(gene name synonym)	psi-mi:ap2a2_rat(display_long)|uniprotkb:Adaptor protein complex AP-2 subunit alpha-2(gene name synonym)|uniprotkb:Alpha2-adaptin(gene name synonym)|uniprotkb:Plasma membrane adaptor HA2/AP2 adaptin alpha C subunit(gene name synonym)|uniprotkb:Alpha-adaptin C(gene name synonym)|uniprotkb:Clathrin assembly protein complex 2 alpha-C large chain(gene name synonym)|uniprotkb:100 kDa coated vesicle protein C(gene name synonym)|uniprotkb:Ap2a2(gene name)|psi-mi:Ap2a2(display_short)|uniprotkb:Adtab(gene name synonym)|uniprotkb:Adaptor-related protein complex 2 subunit alpha-2(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Martins et al. (2018)	imex:IM-28469|pubmed:29476059	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26440627|imex:IM-28469-5	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSRNOG00000016271(gene)|ensembl:ENSRNOT00000023037(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001540"(amyloid-beta binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0010008"(endosome membrane)|go:"GO:0030660"(Golgi-associated vesicle membrane)|go:"GO:0031301"(integral component of organelle membrane)|go:"GO:0042985"(negative regulation of amyloid precursor protein biosynthetic process)|interpro:IPR007084(BRICHOS)|interpro:IPR040145|mint:Q5XIE8|refseq:NP_001006964.1|rgd:620727	rgd:71015|go:"GO:0005886"(plasma membrane)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006898"(receptor-mediated endocytosis)|interpro:IPR002553(Clathrin/coatomer adaptor, adaptin-like, N-terminal)|interpro:IPR003164(Clathrin adaptor, alpha-adaptin, appendage, C-terminal subdomain)|interpro:IPR008152(Clathrin adaptor, alpha/beta/gamma-adaptin, appendage, Ig-like subdomain)|interpro:IPR009028(Clathrin/coatomer adaptor, adaptin-like, appendage, C-terminal subdomain)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR012295(Beta2-adaptin/TATA-box binding, C-terminal)|interpro:IPR013041(Clathrin/coatomer adaptor, adaptin-like, appendage, Ig-like subdomain)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR017104(Adaptor protein complex AP-2, alpha subunit)|rcsb pdb:2VGL|rcsb pdb:2XA7|go:"GO:0008021"(synaptic vesicle)|rcsb pdb:4NEE|rcsb pdb:4UQI|rcsb pdb:6OWT|rcsb pdb:6QH5|rcsb pdb:6QH6|rcsb pdb:6QH7|go:"GO:0019900"(kinase binding)|rcsb pdb:6URI|rcsb pdb:6YAE|rcsb pdb:6YAF|rcsb pdb:6YAH|reactome:R-RNO-177504|reactome:R-RNO-2132295|reactome:R-RNO-416993|reactome:R-RNO-437239|reactome:R-RNO-5099900|reactome:R-RNO-5140745|reactome:R-RNO-6798695|reactome:R-RNO-8856825|go:"GO:0019901"(protein kinase binding)|reactome:R-RNO-8856828|go:"GO:0019904"(protein domain specific binding)|reactome:R-RNO-8866427|reactome:R-RNO-8964038|go:"GO:0030117"(membrane coat)|go:"GO:0030122"(AP-2 adaptor complex)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0035091"(phosphatidylinositol binding)|go:"GO:0035615"(clathrin adaptor activity)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0072583"(clathrin-dependent endocytosis)|go:"GO:0097718"(disordered domain specific binding)|go:"GO:0140312"(cargo adaptor activity)|mint:P18484|dip:DIP-29765N	-	-	-	figure legend:st1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10116(rat-hippocampus)|taxid:10116(Rattus norvegicus hippocampal neurons)	-	2020/10/30	2020/10/30	rogid:DtE+ZXAZKdCMvUW5K+jXQ5bH07M10116	rogid:/3UaX0n3j6Lo0w7GMn0uWzL5GI010116	rigid:zzsc1zNhBb5nwIRPeFpYOKgC3M8	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q5XIE8	uniprotkb:O70511	intact:EBI-15348306|ensembl:ENSRNOP00000023037	intact:EBI-9663355|uniprotkb:Q574D7|uniprotkb:Q574D8|uniprotkb:Q574D9|uniprotkb:Q574E0|uniprotkb:Q574E2|uniprotkb:Q8VDA0	psi-mi:itm2b_rat(display_long)|uniprotkb:Itm2b(gene name)|psi-mi:Itm2b(display_short)|uniprotkb:Immature BRI2(gene name synonym)|uniprotkb:Transmembrane protein BRI(gene name synonym)	psi-mi:ank3_rat(display_long)|uniprotkb:Ank3(gene name)|psi-mi:Ank3(display_short)|uniprotkb:Ankyrin-G(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Martins et al. (2018)	imex:IM-28469|pubmed:29476059	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26440627|imex:IM-28469-5	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSRNOG00000016271(gene)|ensembl:ENSRNOT00000023037(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001540"(amyloid-beta binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0010008"(endosome membrane)|go:"GO:0030660"(Golgi-associated vesicle membrane)|go:"GO:0031301"(integral component of organelle membrane)|go:"GO:0042985"(negative regulation of amyloid precursor protein biosynthetic process)|interpro:IPR007084(BRICHOS)|interpro:IPR040145|mint:Q5XIE8|refseq:NP_001006964.1|rgd:620727	mint:O70511|rgd:620157|refseq:NP_001029156.1|refseq:NP_113993.1|dip:DIP-60342N|go:"GO:0000281"(mitotic cytokinesis)|go:"GO:0005200"(structural constituent of cytoskeleton)|go:"GO:0005764"(lysosome)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005886"(plasma membrane)|go:"GO:0007009"(plasma membrane organization)|go:"GO:0007165"(signal transduction)|go:"GO:0007409"(axonogenesis)|go:"GO:0007411"(axon guidance)|go:"GO:0007528"(neuromuscular junction development)|go:"GO:0008092"(cytoskeletal protein binding)|go:"GO:0009925"(basal plasma membrane)|go:"GO:0009986"(cell surface)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010650"(positive regulation of cell communication by electrical coupling)|go:"GO:0010765"(positive regulation of sodium ion transport)|go:"GO:0010960"(magnesium ion homeostasis)|go:"GO:0014704"(intercalated disc)|go:"GO:0014731"(spectrin-associated cytoskeleton)|go:"GO:0016020"(membrane)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016328"(lateral plasma membrane)|go:"GO:0016529"(sarcoplasmic reticulum)|go:"GO:0019228"(neuronal action potential)|go:"GO:0030018"(Z disc)|go:"GO:0030315"(T-tubule)|go:"GO:0030424"(axon)|go:"GO:0030425"(dendrite)|go:"GO:0030507"(spectrin binding)|go:"GO:0030674"(protein-macromolecule adaptor activity)|go:"GO:0031594"(neuromuscular junction)|go:"GO:0033268"(node of Ranvier)|go:"GO:0033270"(paranode region of axon)|go:"GO:0034112"(positive regulation of homotypic cell-cell adhesion)|go:"GO:0042383"(sarcolemma)|go:"GO:0043001"(Golgi to plasma membrane protein transport)|go:"GO:0043005"(neuron projection)|go:"GO:0043034"(costamere)|go:"GO:0043266"(regulation of potassium ion transport)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0045162"(clustering of voltage-gated sodium channels)|go:"GO:0045184"(establishment of protein localization)|go:"GO:0045202"(synapse)|go:"GO:0045211"(postsynaptic membrane)|go:"GO:0045296"(cadherin binding)|go:"GO:0045838"(positive regulation of membrane potential)|go:"GO:0050808"(synapse organization)|go:"GO:0071286"(cellular response to magnesium ion)|go:"GO:0071709"(membrane assembly)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0072660"(maintenance of protein location in plasma membrane)|go:"GO:0090314"(positive regulation of protein targeting to membrane)|go:"GO:0099612"(protein localization to axon)|go:"GO:0140031"(phosphorylation-dependent protein binding)|go:"GO:1900827"(positive regulation of membrane depolarization during cardiac muscle cell action potential)|go:"GO:1902260"(negative regulation of delayed rectifier potassium channel activity)|go:"GO:2000651"(positive regulation of sodium ion transmembrane transporter activity)|go:"GO:2001259"(positive regulation of cation channel activity)|interpro:IPR000488(Death)|interpro:IPR000906(ZU5)|interpro:IPR002110(Ankyrin)|interpro:IPR011029(DEATH-like)|interpro:IPR020683|interpro:IPR036770|interpro:IPR037971|interpro:IPR040745|rcsb pdb:5YIP|rcsb pdb:5YIQ|rcsb pdb:6A9X|rcsb pdb:6M3P|rcsb pdb:6M3R|go:"GO:0043194"(axon initial segment)	-	-	-	figure legend:st1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10116(rat-hippocampus)|taxid:10116(Rattus norvegicus hippocampal neurons)	-	2020/10/30	2020/10/30	rogid:DtE+ZXAZKdCMvUW5K+jXQ5bH07M10116	rogid:FloqiVqbDqo4HEvTwKuGl7Q0Cxw10116	rigid:zzsc1zNhBb5nwIRPeFpYOKgC3M8	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q5XIE8	uniprotkb:O08838	intact:EBI-15348306|ensembl:ENSRNOP00000023037	intact:EBI-80080	psi-mi:itm2b_rat(display_long)|uniprotkb:Itm2b(gene name)|psi-mi:Itm2b(display_short)|uniprotkb:Immature BRI2(gene name synonym)|uniprotkb:Transmembrane protein BRI(gene name synonym)	psi-mi:amph_rat(display_long)|uniprotkb:Amph(gene name)|psi-mi:Amph(display_short)|uniprotkb:Amph1(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Martins et al. (2018)	imex:IM-28469|pubmed:29476059	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26440627|imex:IM-28469-5	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSRNOG00000016271(gene)|ensembl:ENSRNOT00000023037(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001540"(amyloid-beta binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0010008"(endosome membrane)|go:"GO:0030660"(Golgi-associated vesicle membrane)|go:"GO:0031301"(integral component of organelle membrane)|go:"GO:0042985"(negative regulation of amyloid precursor protein biosynthetic process)|interpro:IPR007084(BRICHOS)|interpro:IPR040145|mint:Q5XIE8|refseq:NP_001006964.1|rgd:620727	go:"GO:0045807"(positive regulation of endocytosis)|go:"GO:0048488"(synaptic vesicle endocytosis)|go:"GO:0005543"(phospholipid binding)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005886"(plasma membrane)|go:"GO:0007612"(learning)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0031256"(leading edge membrane)|go:"GO:0043195"(terminal bouton)|go:"GO:0043547"(positive regulation of GTPase activity)|go:"GO:0043679"(axon terminus)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0098684"(photoreceptor ribbon synapse)|go:"GO:0098793"(presynapse)|go:"GO:0098833"(presynaptic endocytic zone)|go:"GO:0098850"(extrinsic component of synaptic vesicle membrane)|go:"GO:0098978"(glutamatergic synapse)|interpro:IPR001452(Src homology-3)|interpro:IPR003005(Amphiphysin)|interpro:IPR003017(Amphiphysin, isoform 1)|interpro:IPR004148(BAR)|interpro:IPR027267|interpro:IPR035470|interpro:IPR036028|rcsb pdb:2VJ0|rcsb pdb:5M5T|reactome:R-RNO-8856828|rgd:620274|refseq:NP_071553.1|mint:O08838|dip:DIP-30977N	-	-	-	figure legend:st1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10116(rat-hippocampus)|taxid:10116(Rattus norvegicus hippocampal neurons)	-	2020/10/30	2020/10/30	rogid:DtE+ZXAZKdCMvUW5K+jXQ5bH07M10116	rogid:wTANhsy4BxCZYbSIhwlrr+m9Tt810116	rigid:zzsc1zNhBb5nwIRPeFpYOKgC3M8	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q5XIE8	uniprotkb:P23565	intact:EBI-15348306|ensembl:ENSRNOP00000023037	intact:EBI-6899875	psi-mi:itm2b_rat(display_long)|uniprotkb:Itm2b(gene name)|psi-mi:Itm2b(display_short)|uniprotkb:Immature BRI2(gene name synonym)|uniprotkb:Transmembrane protein BRI(gene name synonym)	psi-mi:ainx_rat(display_long)|uniprotkb:Ina(gene name)|psi-mi:Ina(display_short)|uniprotkb:Inexa(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Martins et al. (2018)	imex:IM-28469|pubmed:29476059	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26440627|imex:IM-28469-5	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSRNOG00000016271(gene)|ensembl:ENSRNOT00000023037(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001540"(amyloid-beta binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0010008"(endosome membrane)|go:"GO:0030660"(Golgi-associated vesicle membrane)|go:"GO:0031301"(integral component of organelle membrane)|go:"GO:0042985"(negative regulation of amyloid precursor protein biosynthetic process)|interpro:IPR007084(BRICHOS)|interpro:IPR040145|mint:Q5XIE8|refseq:NP_001006964.1|rgd:620727	go:"GO:0099160"(postsynaptic intermediate filament cytoskeleton)|go:"GO:0099184"(structural constituent of postsynaptic intermediate filament cytoskeleton)|go:"GO:1990830"(cellular response to leukemia inhibitory factor)|go:"GO:0005883"(neurofilament)|go:"GO:0007399"(nervous system development)|go:"GO:0030154"(cell differentiation)|go:"GO:0036464"(cytoplasmic ribonucleoprotein granule)|go:"GO:0042246"(tissue regeneration)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045104"(intermediate filament cytoskeleton organization)|go:"GO:0060052"(neurofilament cytoskeleton organization)|go:"GO:0098685"(Schaffer collateral - CA1 synapse)|go:"GO:0098794"(postsynapse)|go:"GO:0098973"(structural constituent of postsynaptic actin cytoskeleton)|go:"GO:0098978"(glutamatergic synapse)|interpro:IPR006821(Intermediate filament, DNA-binding region)|interpro:IPR018039|rgd:2911|mint:P23565|interpro:IPR027703|interpro:IPR039008	-	-	-	figure legend:st1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10116(rat-hippocampus)|taxid:10116(Rattus norvegicus hippocampal neurons)	-	2020/10/30	2020/10/30	rogid:DtE+ZXAZKdCMvUW5K+jXQ5bH07M10116	rogid:4qBkIm9ifAEYegj00H2EUgBCn0w10116	rigid:zzsc1zNhBb5nwIRPeFpYOKgC3M8	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q5XIE8	uniprotkb:P06238	intact:EBI-15348306|ensembl:ENSRNOP00000023037	intact:EBI-15184861|ensembl:ENSRNOP00000019346|ensembl:ENSRNOP00000066130|uniprotkb:Q4FZY3	psi-mi:itm2b_rat(display_long)|uniprotkb:Itm2b(gene name)|psi-mi:Itm2b(display_short)|uniprotkb:Immature BRI2(gene name synonym)|uniprotkb:Transmembrane protein BRI(gene name synonym)	psi-mi:a2mg_rat(display_long)|uniprotkb:A2m(gene name)|psi-mi:A2m(display_short)|uniprotkb:A2m1(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Martins et al. (2018)	imex:IM-28469|pubmed:29476059	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26440627|imex:IM-28469-5	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSRNOG00000016271(gene)|ensembl:ENSRNOT00000023037(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001540"(amyloid-beta binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0010008"(endosome membrane)|go:"GO:0030660"(Golgi-associated vesicle membrane)|go:"GO:0031301"(integral component of organelle membrane)|go:"GO:0042985"(negative regulation of amyloid precursor protein biosynthetic process)|interpro:IPR007084(BRICHOS)|interpro:IPR040145|mint:Q5XIE8|refseq:NP_001006964.1|rgd:620727	ensembl:ENSRNOG00000028896(gene)|ensembl:ENSRNOG00000045772(gene)|ensembl:ENSRNOT00000019346(transcript)|ensembl:ENSRNOT00000075799(transcript)|go:"GO:0001553"(luteinization)|go:"GO:0001869"(negative regulation of complement activation, lectin pathway)|go:"GO:0002020"(protease binding)|go:"GO:0002438"(acute inflammatory response to antigenic stimulus)|go:"GO:0004866"(endopeptidase inhibitor activity)|go:"GO:0004867"(serine-type endopeptidase inhibitor activity)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005615"(extracellular space)|go:"GO:0006953"(acute-phase response)|go:"GO:0007584"(response to nutrient)|interpro:IPR002890(Alpha-2-macroglobulin, N-terminal)|interpro:IPR008930(Terpenoid cylases/protein prenyltransferase alpha-alpha toroid)|interpro:IPR009048(Alpha-macroglobulin, receptor-binding)|interpro:IPR011625(Alpha-2-macroglobulin, N-terminal 2)|interpro:IPR011626(A-macroglobulin complement component)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR014756(Immunoglobulin E-set)|interpro:IPR019742|interpro:IPR036595|interpro:IPR040839|interpro:IPR041555|interpro:IPR041813|mint:P06238|reactome:R-RNO-114608|reactome:R-RNO-140837|reactome:R-RNO-1474228|reactome:R-RNO-8963896|interpro:IPR001599(Alpha-2-macroglobulin)|go:"GO:0010037"(response to carbon dioxide)|go:"GO:0010951"(negative regulation of endopeptidase activity)|go:"GO:0019838"(growth factor binding)|go:"GO:0019899"(enzyme binding)|go:"GO:0019959"(interleukin-8 binding)|go:"GO:0019966"(interleukin-1 binding)|go:"GO:0034695"(response to prostaglandin E)|go:"GO:0042802"(identical protein binding)|go:"GO:0043120"(tumor necrosis factor binding)|go:"GO:0048306"(calcium-dependent protein binding)|go:"GO:0048403"(brain-derived neurotrophic factor binding)|go:"GO:0048406"(nerve growth factor binding)|go:"GO:0048863"(stem cell differentiation)|go:"GO:0051384"(response to glucocorticoid)|go:"GO:1990402"(embryonic liver development)|go:"GO:0009611"(response to wounding)|refseq:NP_036620.2|refseq:XP_003749876.1|rgd:2004	-	-	-	figure legend:st1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10116(rat-hippocampus)|taxid:10116(Rattus norvegicus hippocampal neurons)	-	2020/10/30	2020/10/30	rogid:DtE+ZXAZKdCMvUW5K+jXQ5bH07M10116	rogid:MAZi2KkXU2jKuLSeqwT1dNJlrY010116	rigid:zzsc1zNhBb5nwIRPeFpYOKgC3M8	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q5XIE8	uniprotkb:P63269	intact:EBI-15348306|ensembl:ENSRNOP00000023037	intact:EBI-297811|uniprotkb:P12718|ensembl:ENSRNOP00000050322	psi-mi:itm2b_rat(display_long)|uniprotkb:Itm2b(gene name)|psi-mi:Itm2b(display_short)|uniprotkb:Immature BRI2(gene name synonym)|uniprotkb:Transmembrane protein BRI(gene name synonym)	psi-mi:acth_rat(display_long)|uniprotkb:Actg2(gene name)|psi-mi:Actg2(display_short)|uniprotkb:Acta3(gene name synonym)|uniprotkb:Actsg(gene name synonym)|uniprotkb:Smooth muscle gamma-actin(gene name synonym)|uniprotkb:Gamma-2-actin(gene name synonym)|uniprotkb:Alpha-actin-3(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Martins et al. (2018)	imex:IM-28469|pubmed:29476059	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26440627|imex:IM-28469-5	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSRNOG00000016271(gene)|ensembl:ENSRNOT00000023037(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001540"(amyloid-beta binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0010008"(endosome membrane)|go:"GO:0030660"(Golgi-associated vesicle membrane)|go:"GO:0031301"(integral component of organelle membrane)|go:"GO:0042985"(negative regulation of amyloid precursor protein biosynthetic process)|interpro:IPR007084(BRICHOS)|interpro:IPR040145|mint:Q5XIE8|refseq:NP_001006964.1|rgd:620727	ensembl:ENSRNOG00000029401(gene)|ensembl:ENSRNOT00000042699(transcript)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005869"(dynactin complex)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0014829"(vascular associated smooth muscle contraction)|go:"GO:0030027"(lamellipodium)|go:"GO:0030175"(filopodium)|go:"GO:0032982"(myosin filament)|go:"GO:0044297"(cell body)|go:"GO:0071944"(cell periphery)|go:"GO:0090131"(mesenchyme migration)|interpro:IPR004000(Actin/actin-like)|interpro:IPR004001(Actin, conserved site)|interpro:IPR020902|interpro:IPR043129|mint:P63269|reactome:R-RNO-445355|rgd:2027|refseq:NP_037025.1|refseq:XP_006236790.1	-	-	-	figure legend:st1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10116(rat-hippocampus)|taxid:10116(Rattus norvegicus hippocampal neurons)	-	2020/10/30	2020/10/30	rogid:DtE+ZXAZKdCMvUW5K+jXQ5bH07M10116	rogid:tp0JsXhrGsRl5i4Wg2dyaPGUPxA10116	rigid:zzsc1zNhBb5nwIRPeFpYOKgC3M8	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q5XIE8	uniprotkb:P60711	intact:EBI-15348306|ensembl:ENSRNOP00000023037	intact:EBI-349272|uniprotkb:Q64316|uniprotkb:P02570|uniprotkb:P70514|uniprotkb:P99021|uniprotkb:Q11211|ensembl:ENSRNOP00000044296	psi-mi:itm2b_rat(display_long)|uniprotkb:Itm2b(gene name)|psi-mi:Itm2b(display_short)|uniprotkb:Immature BRI2(gene name synonym)|uniprotkb:Transmembrane protein BRI(gene name synonym)	psi-mi:actb_rat(display_long)|uniprotkb:Actb(gene name)|psi-mi:Actb(display_short)|uniprotkb:Beta-actin(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Martins et al. (2018)	imex:IM-28469|pubmed:29476059	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26440627|imex:IM-28469-5	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSRNOG00000016271(gene)|ensembl:ENSRNOT00000023037(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001540"(amyloid-beta binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0010008"(endosome membrane)|go:"GO:0030660"(Golgi-associated vesicle membrane)|go:"GO:0031301"(integral component of organelle membrane)|go:"GO:0042985"(negative regulation of amyloid precursor protein biosynthetic process)|interpro:IPR007084(BRICHOS)|interpro:IPR040145|mint:Q5XIE8|refseq:NP_001006964.1|rgd:620727	rgd:628837|refseq:NP_112406.1|ensembl:ENSRNOG00000034254(gene)|ensembl:ENSRNOT00000042459(transcript)|go:"GO:0000079"(regulation of cyclin-dependent protein serine/threonine kinase activity)|go:"GO:0001725"(stress fiber)|go:"GO:0001738"(morphogenesis of a polarized epithelium)|go:"GO:0002102"(podosome)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005884"(actin filament)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005912"(adherens junction)|go:"GO:0005925"(focal adhesion)|go:"GO:0007163"(establishment or maintenance of cell polarity)|go:"GO:0007409"(axonogenesis)|go:"GO:0007623"(circadian rhythm)|go:"GO:0009612"(response to mechanical stimulus)|go:"GO:0014069"(postsynaptic density)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0016020"(membrane)|go:"GO:0019894"(kinesin binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0022898"(regulation of transmembrane transporter activity)|go:"GO:0030027"(lamellipodium)|go:"GO:0030424"(axon)|go:"GO:0030863"(cortical cytoskeleton)|go:"GO:0030957"(Tat protein binding)|go:"GO:0032091"(negative regulation of protein binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034333"(adherens junction assembly)|go:"GO:0035902"(response to immobilization stress)|go:"GO:0036464"(cytoplasmic ribonucleoprotein granule)|go:"GO:0042802"(identical protein binding)|go:"GO:0043296"(apical junction complex)|go:"GO:0044305"(calyx of Held)|go:"GO:0045121"(membrane raft)|go:"GO:0045176"(apical protein localization)|go:"GO:0045202"(synapse)|go:"GO:0048488"(synaptic vesicle endocytosis)|go:"GO:0048870"(cell motility)|go:"GO:0050998"(nitric-oxide synthase binding)|go:"GO:0051621"(regulation of norepinephrine uptake)|go:"GO:0060041"(retina development in camera-type eye)|go:"GO:0070160"(tight junction)|go:"GO:0071257"(cellular response to electrical stimulus)|go:"GO:0071896"(protein localization to adherens junction)|go:"GO:0072749"(cellular response to cytochalasin B)|go:"GO:0097433"(dense body)|go:"GO:0098685"(Schaffer collateral - CA1 synapse)|go:"GO:0098871"(postsynaptic actin cytoskeleton)|go:"GO:0035267"(NuA4 histone acetyltransferase complex)|go:"GO:0098973"(structural constituent of postsynaptic actin cytoskeleton)|reactome:R-RNO-190873|reactome:R-RNO-196025|go:"GO:0098974"(postsynaptic actin cytoskeleton organization)|reactome:R-RNO-2029482|reactome:R-RNO-3928662|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0150111"(regulation of transepithelial transport)|reactome:R-RNO-418990|reactome:R-RNO-437239|go:"GO:1903076"(regulation of protein localization to plasma membrane)|reactome:R-RNO-4420097|reactome:R-RNO-445095|reactome:R-RNO-446353|reactome:R-RNO-5250924|reactome:R-RNO-5626467|reactome:R-RNO-5663213|reactome:R-RNO-5663220|reactome:R-RNO-5674135|reactome:R-RNO-5689603|reactome:R-RNO-5696394|reactome:R-RNO-8856828|reactome:R-RNO-9035034|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR004000(Actin/actin-like)|interpro:IPR004001(Actin, conserved site)|interpro:IPR020902|interpro:IPR043129|mint:P60711	-	-	-	figure legend:st1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10116(rat-hippocampus)|taxid:10116(Rattus norvegicus hippocampal neurons)	-	2020/10/30	2020/10/30	rogid:DtE+ZXAZKdCMvUW5K+jXQ5bH07M10116	rogid:Hoge1B8Pn56kvbNTpkSLsQuHwRc10116	rigid:zzsc1zNhBb5nwIRPeFpYOKgC3M8	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q5XIE8	uniprotkb:P06761	intact:EBI-15348306|ensembl:ENSRNOP00000023037	intact:EBI-916036|ensembl:ENSRNOP00000025064	psi-mi:itm2b_rat(display_long)|uniprotkb:Itm2b(gene name)|psi-mi:Itm2b(display_short)|uniprotkb:Immature BRI2(gene name synonym)|uniprotkb:Transmembrane protein BRI(gene name synonym)	psi-mi:bip_rat(display_long)|uniprotkb:Hspa5(gene name)|psi-mi:Hspa5(display_short)|uniprotkb:Grp78(gene name synonym)|uniprotkb:Immunoglobulin heavy chain-binding protein(gene name synonym)|uniprotkb:Steroidogenesis-activator polypeptide(gene name synonym)|uniprotkb:78 kDa glucose-regulated protein(gene name synonym)|uniprotkb:Binding-immunoglobulin protein(gene name synonym)|uniprotkb:Heat shock protein 70 family protein 5(gene name synonym)|uniprotkb:Heat shock protein family A member 5(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Martins et al. (2018)	imex:IM-28469|pubmed:29476059	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26440627|imex:IM-28469-5	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSRNOG00000016271(gene)|ensembl:ENSRNOT00000023037(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001540"(amyloid-beta binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0010008"(endosome membrane)|go:"GO:0030660"(Golgi-associated vesicle membrane)|go:"GO:0031301"(integral component of organelle membrane)|go:"GO:0042985"(negative regulation of amyloid precursor protein biosynthetic process)|interpro:IPR007084(BRICHOS)|interpro:IPR040145|mint:Q5XIE8|refseq:NP_001006964.1|rgd:620727	rgd:2843|refseq:NP_037215.1|ensembl:ENSRNOG00000018294(gene)|ensembl:ENSRNOT00000025067(transcript)|go:"GO:0001554"(luteolysis)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005788"(endoplasmic reticulum lumen)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005790"(smooth endoplasmic reticulum)|go:"GO:0005793"(endoplasmic reticulum-Golgi intermediate compartment)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006983"(ER overload response)|go:"GO:0008180"(COP9 signalosome)|go:"GO:0009314"(response to radiation)|go:"GO:0009986"(cell surface)|go:"GO:0010976"(positive regulation of neuron projection development)|go:"GO:0016020"(membrane)|go:"GO:0019899"(enzyme binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0021589"(cerebellum structural organization)|go:"GO:0021680"(cerebellar Purkinje cell layer development)|go:"GO:0030176"(integral component of endoplasmic reticulum membrane)|go:"GO:0030182"(neuron differentiation)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0030433"(ubiquitin-dependent ERAD pathway)|go:"GO:0030496"(midbody)|go:"GO:0030512"(negative regulation of transforming growth factor beta receptor signaling pathway)|go:"GO:0030968"(endoplasmic reticulum unfolded protein response)|go:"GO:0031072"(heat shock protein binding)|go:"GO:0031204"(posttranslational protein targeting to membrane, translocation)|go:"GO:0031333"(negative regulation of protein-containing complex assembly)|go:"GO:0031398"(positive regulation of protein ubiquitination)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034620"(cellular response to unfolded protein)|go:"GO:0034663"(endoplasmic reticulum chaperone complex)|go:"GO:0034976"(response to endoplasmic reticulum stress)|go:"GO:0035437"(maintenance of protein localization in endoplasmic reticulum)|go:"GO:0035690"|go:"GO:0036498"(IRE1-mediated unfolded protein response)|go:"GO:0042026"(protein refolding)|go:"GO:0042149"(cellular response to glucose starvation)|go:"GO:0042220"(response to cocaine)|go:"GO:0043022"(ribosome binding)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0044183"(protein folding chaperone)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0051085"(chaperone cofactor-dependent protein refolding)|go:"GO:0051402"(neuron apoptotic process)|go:"GO:0051603"(proteolysis involved in cellular protein catabolic process)|go:"GO:0051787"(misfolded protein binding)|go:"GO:0071236"(cellular response to antibiotic)|go:"GO:0071277"(cellular response to calcium ion)|go:"GO:0071287"(cellular response to manganese ion)|go:"GO:0071320"(cellular response to cAMP)|go:"GO:0071353"(cellular response to interleukin-4)|go:"GO:0071480"(cellular response to gamma radiation)|go:"GO:0097501"(stress response to metal ion)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|go:"GO:1901998"(toxin transport)|go:"GO:1903895"(negative regulation of IRE1-mediated unfolded protein response)|go:"GO:1904313"(response to methamphetamine hydrochloride)|go:"GO:1990090"(cellular response to nerve growth factor stimulus)|interpro:IPR013126(Heat shock protein 70)|interpro:IPR018181|interpro:IPR029047|interpro:IPR029048|interpro:IPR042050|interpro:IPR043129|mint:P06761|reactome:R-RNO-3371453|reactome:R-RNO-983170	-	-	-	figure legend:st1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10116(rat-hippocampus)|taxid:10116(Rattus norvegicus hippocampal neurons)	-	2020/10/30	2020/10/30	rogid:DtE+ZXAZKdCMvUW5K+jXQ5bH07M10116	rogid:5HRXkoNHYJvBA2iejRqltGRdJDw10116	rigid:zzsc1zNhBb5nwIRPeFpYOKgC3M8	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q5XIE8	uniprotkb:P62909	intact:EBI-15348306|ensembl:ENSRNOP00000023037	intact:EBI-432553|uniprotkb:P17073|uniprotkb:P47933|ensembl:ENSRNOP00000023935	psi-mi:itm2b_rat(display_long)|uniprotkb:Itm2b(gene name)|psi-mi:Itm2b(display_short)|uniprotkb:Immature BRI2(gene name synonym)|uniprotkb:Transmembrane protein BRI(gene name synonym)	psi-mi:rs3_rat(display_long)|uniprotkb:Rps3(gene name)|psi-mi:Rps3(display_short)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Martins et al. (2018)	imex:IM-28469|pubmed:29476059	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26440627|imex:IM-28469-5	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSRNOG00000016271(gene)|ensembl:ENSRNOT00000023037(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001540"(amyloid-beta binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0010008"(endosome membrane)|go:"GO:0030660"(Golgi-associated vesicle membrane)|go:"GO:0031301"(integral component of organelle membrane)|go:"GO:0042985"(negative regulation of amyloid precursor protein biosynthetic process)|interpro:IPR007084(BRICHOS)|interpro:IPR040145|mint:Q5XIE8|refseq:NP_001006964.1|rgd:620727	rgd:619888|refseq:NP_001009239.1|ensembl:ENSRNOG00000017418(gene)|ensembl:ENSRNOT00000023935(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0003684"(damaged DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0003906"("DNA-(apurinic or apyrimidinic site) endonuclease activity")|go:"GO:0004520"(endodeoxyribonuclease activity)|go:"GO:0005634"(nucleus)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0005829"(cytosol)|go:"GO:0005840"(ribosome)|go:"GO:0005844"(polysome)|go:"GO:0005886"(plasma membrane)|go:"GO:0006281"(DNA repair)|go:"GO:0006412"(translation)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0006915"(apoptotic process)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0007059"(chromosome segregation)|go:"GO:0008017"(microtubule binding)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0012505"(endomembrane system)|go:"GO:0014069"(postsynaptic density)|go:"GO:0015631"(tubulin binding)|go:"GO:0017148"(negative regulation of translation)|go:"GO:0019899"(enzyme binding)|go:"GO:0019900"(kinase binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0022626"(cytosolic ribosome)|go:"GO:0022627"(cytosolic small ribosomal subunit)|go:"GO:0030425"(dendrite)|go:"GO:0030544"(Hsp70 protein binding)|go:"GO:0031116"(positive regulation of microtubule polymerization)|go:"GO:0031334"(positive regulation of protein-containing complex assembly)|go:"GO:0031397"(negative regulation of protein ubiquitination)|go:"GO:0032079"(positive regulation of endodeoxyribonuclease activity)|go:"GO:0032357"(oxidized purine DNA binding)|go:"GO:0032358"(oxidized pyrimidine DNA binding)|go:"GO:0032587"(ruffle membrane)|go:"GO:0032743"(positive regulation of interleukin-2 production)|go:"GO:0034614"(cellular response to reactive oxygen species)|go:"GO:0042104"(positive regulation of activated T cell proliferation)|go:"GO:0042769"(obsolete DNA damage response, detection of DNA damage)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0043507"(positive regulation of JUN kinase activity)|go:"GO:0044390"(ubiquitin-like protein conjugating enzyme binding)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045202"(synapse)|go:"GO:0045738"(negative regulation of DNA repair)|go:"GO:0045739"(positive regulation of DNA repair)|go:"GO:0050862"(positive regulation of T cell receptor signaling pathway)|go:"GO:0051018"(protein kinase A binding)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|go:"GO:0051225"(spindle assembly)|go:"GO:0051301"(cell division)|go:"GO:0051879"(Hsp90 protein binding)|go:"GO:0061481"(response to TNF agonist)|go:"GO:0070181"(small ribosomal subunit rRNA binding)|go:"GO:0070301"(cellular response to hydrogen peroxide)|go:"GO:0071159"(NF-kappaB complex)|go:"GO:0071356"(cellular response to tumor necrosis factor)|go:"GO:0072686"(mitotic spindle)|go:"GO:0097100"(supercoiled DNA binding)|go:"GO:0140078"("class I DNA-(apurinic or apyrimidinic site) endonuclease activity")|go:"GO:1901224"(positive regulation of NIK/NF-kappaB signaling)|go:"GO:1902231"(positive regulation of intrinsic apoptotic signaling pathway in response to DNA damage)|go:"GO:1902546"(positive regulation of DNA N-glycosylase activity)|go:"GO:2001235"(positive regulation of apoptotic signaling pathway)|go:"GO:2001272"(positive regulation of cysteine-type endopeptidase activity involved in execution phase of apoptosis)|interpro:IPR001351(Ribosomal protein S3, C-terminal)|interpro:IPR004044(K Homology, type 2)|interpro:IPR005703(Ribosomal protein S3, eukaryotic/archaeal)|interpro:IPR009019(K Homology, prokaryotic type)|interpro:IPR015946(K homology-like, alpha/beta)|go:"GO:1905053"(positive regulation of base-excision repair)|go:"GO:1990090"(cellular response to nerve growth factor stimulus)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR018280|interpro:IPR036419|mint:P62909|reactome:R-RNO-156827|reactome:R-RNO-1799339|reactome:R-RNO-6791226|reactome:R-RNO-72649|reactome:R-RNO-72689|reactome:R-RNO-72695|reactome:R-RNO-72702|reactome:R-RNO-72706|reactome:R-RNO-975956|reactome:R-RNO-975957	-	-	-	figure legend:st1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10116(rat-hippocampus)|taxid:10116(Rattus norvegicus hippocampal neurons)	-	2020/10/30	2020/10/30	rogid:DtE+ZXAZKdCMvUW5K+jXQ5bH07M10116	rogid:f4Vh6HESE+lKZinjkJ883IG3wiY10116	rigid:zzsc1zNhBb5nwIRPeFpYOKgC3M8	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q5XIE8	uniprotkb:P86252	intact:EBI-15348306|ensembl:ENSRNOP00000023037	intact:EBI-1638520	psi-mi:itm2b_rat(display_long)|uniprotkb:Itm2b(gene name)|psi-mi:Itm2b(display_short)|uniprotkb:Immature BRI2(gene name synonym)|uniprotkb:Transmembrane protein BRI(gene name synonym)	psi-mi:pura_rat(display_long)|uniprotkb:Pura(gene name)|psi-mi:Pura(display_short)|uniprotkb:Purine-rich single-stranded DNA-binding protein alpha(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Martins et al. (2018)	imex:IM-28469|pubmed:29476059	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26440627|imex:IM-28469-5	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSRNOG00000016271(gene)|ensembl:ENSRNOT00000023037(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001540"(amyloid-beta binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0010008"(endosome membrane)|go:"GO:0030660"(Golgi-associated vesicle membrane)|go:"GO:0031301"(integral component of organelle membrane)|go:"GO:0042985"(negative regulation of amyloid precursor protein biosynthetic process)|interpro:IPR007084(BRICHOS)|interpro:IPR040145|mint:Q5XIE8|refseq:NP_001006964.1|rgd:620727	interpro:IPR006628(PUR-alpha/beta/gamma, DNA/RNA-binding)|rgd:1308543|mint:P86252|interpro:IPR030500|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000900"(translation repressor activity, mRNA regulatory element binding)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0003677"(DNA binding)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0003691"(double-stranded telomeric DNA binding)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006268"(DNA unwinding involved in DNA replication)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007399"(nervous system development)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0014069"(postsynaptic density)|go:"GO:0030154"(cell differentiation)|go:"GO:0030425"(dendrite)|go:"GO:0032422"(purine-rich negative regulatory element binding)|go:"GO:0032839"(dendrite cytoplasm)|go:"GO:0043025"(neuronal cell body)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0046332"(SMAD binding)|go:"GO:0046651"(lymphocyte proliferation)|go:"GO:0050673"(epithelial cell proliferation)|go:"GO:0098794"(postsynapse)|go:"GO:0098963"(dendritic transport of messenger ribonucleoprotein complex)|go:"GO:0098978"(glutamatergic synapse)	-	-	-	figure legend:st1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10116(rat-hippocampus)|taxid:10116(Rattus norvegicus hippocampal neurons)	-	2020/10/30	2020/10/30	rogid:DtE+ZXAZKdCMvUW5K+jXQ5bH07M10116	rogid:S+5CDoCwS0nqAB0KlkB+AzxN7Ks10116	rigid:zzsc1zNhBb5nwIRPeFpYOKgC3M8	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q5XIE8	uniprotkb:P16036	intact:EBI-15348306|ensembl:ENSRNOP00000023037	intact:EBI-916656	psi-mi:itm2b_rat(display_long)|uniprotkb:Itm2b(gene name)|psi-mi:Itm2b(display_short)|uniprotkb:Immature BRI2(gene name synonym)|uniprotkb:Transmembrane protein BRI(gene name synonym)	psi-mi:mpcp_rat(display_long)|uniprotkb:Phosphate transport protein(gene name synonym)|uniprotkb:Solute carrier family 25 member 3(gene name synonym)|uniprotkb:Slc25a3(gene name)|psi-mi:Slc25a3(display_short)|uniprotkb:Phc(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Martins et al. (2018)	imex:IM-28469|pubmed:29476059	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26440627|imex:IM-28469-5	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSRNOG00000016271(gene)|ensembl:ENSRNOT00000023037(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001540"(amyloid-beta binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0010008"(endosome membrane)|go:"GO:0030660"(Golgi-associated vesicle membrane)|go:"GO:0031301"(integral component of organelle membrane)|go:"GO:0042985"(negative regulation of amyloid precursor protein biosynthetic process)|interpro:IPR007084(BRICHOS)|interpro:IPR040145|mint:Q5XIE8|refseq:NP_001006964.1|rgd:620727	rgd:70986|interpro:IPR018108|interpro:IPR023395|mint:P16036|interpro:IPR044677|go:"GO:0005315"(inorganic phosphate transmembrane transporter activity)|go:"GO:0005739"(mitochondrion)|go:"GO:0015317"("phosphate:proton symporter activity")|go:"GO:0031305"(integral component of mitochondrial inner membrane)|go:"GO:0035435"(phosphate ion transmembrane transport)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:1990547"(mitochondrial phosphate ion transmembrane transport)	-	-	-	figure legend:st1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10116(rat-hippocampus)|taxid:10116(Rattus norvegicus hippocampal neurons)	-	2020/10/30	2020/10/30	rogid:DtE+ZXAZKdCMvUW5K+jXQ5bH07M10116	rogid:BwRf4GKI4G+aBu3r29CqmCdOHyM10116	rigid:zzsc1zNhBb5nwIRPeFpYOKgC3M8	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q5XIE8	uniprotkb:P61980	intact:EBI-15348306|ensembl:ENSRNOP00000023037	intact:EBI-299761|ensembl:ENSRNOP00000025915|uniprotkb:Q07244|uniprotkb:Q15671|uniprotkb:Q60577|uniprotkb:Q922Y7|uniprotkb:Q96J62	psi-mi:itm2b_rat(display_long)|uniprotkb:Itm2b(gene name)|psi-mi:Itm2b(display_short)|uniprotkb:Immature BRI2(gene name synonym)|uniprotkb:Transmembrane protein BRI(gene name synonym)	psi-mi:hnrpk_rat(display_long)|uniprotkb:Hnrnpk(gene name)|psi-mi:Hnrnpk(display_short)|uniprotkb:Hnrpk(gene name synonym)|uniprotkb:dC stretch-binding protein(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Martins et al. (2018)	imex:IM-28469|pubmed:29476059	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26440627|imex:IM-28469-5	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSRNOG00000016271(gene)|ensembl:ENSRNOT00000023037(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001540"(amyloid-beta binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0010008"(endosome membrane)|go:"GO:0030660"(Golgi-associated vesicle membrane)|go:"GO:0031301"(integral component of organelle membrane)|go:"GO:0042985"(negative regulation of amyloid precursor protein biosynthetic process)|interpro:IPR007084(BRICHOS)|interpro:IPR040145|mint:Q5XIE8|refseq:NP_001006964.1|rgd:620727	ensembl:ENSRNOG00000019113(gene)|ensembl:ENSRNOT00000025916(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000987"(cis-regulatory region sequence-specific DNA binding)|go:"GO:0001541"(ovarian follicle development)|go:"GO:0001822"(kidney development)|go:"GO:0001889"(liver development)|go:"GO:0002102"(podosome)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0003730"(mRNA 3'-UTR binding)|go:"GO:0005521"(lamin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0005938"(cell cortex)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006397"(mRNA processing)|go:"GO:0006953"(acute-phase response)|go:"GO:0007417"(central nervous system development)|go:"GO:0007422"(peripheral nervous system development)|go:"GO:0007568"(aging)|go:"GO:0008380"(RNA splicing)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0010494"(cytoplasmic stress granule)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0010976"(positive regulation of neuron projection development)|go:"GO:0010988"(regulation of low-density lipoprotein particle clearance)|go:"GO:0014069"(postsynaptic density)|go:"GO:0014823"(response to activity)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0021549"(cerebellum development)|go:"GO:0021766"(hippocampus development)|go:"GO:0021987"(cerebral cortex development)|go:"GO:0030324"(lung development)|go:"GO:0030628"(pre-mRNA 3'-splice site binding)|go:"GO:0031072"(heat shock protein binding)|go:"GO:0000785"(chromatin)|go:"GO:0032869"(cellular response to insulin stimulus)|go:"GO:0032993"(protein-DNA complex)|go:"GO:0033120"(positive regulation of RNA splicing)|go:"GO:0042802"(identical protein binding)|go:"GO:0042805"(actinin binding)|go:"GO:0043010"(camera-type eye development)|go:"GO:0043021"(ribonucleoprotein complex binding)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043197"(dendritic spine)|go:"GO:0043679"(axon terminus)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048024"(regulation of mRNA splicing, via spliceosome)|go:"GO:0048025"(negative regulation of mRNA splicing, via spliceosome)|go:"GO:0048260"(positive regulation of receptor-mediated endocytosis)|go:"GO:0048538"(thymus development)|go:"GO:0050804"(modulation of chemical synaptic transmission)|go:"GO:0050806"(positive regulation of synaptic transmission)|go:"GO:0051117"(ATPase binding)|go:"GO:0060999"(positive regulation of dendritic spine development)|go:"GO:0071013"(catalytic step 2 spliceosome)|go:"GO:0071230"(cellular response to amino acid stimulus)|go:"GO:0071333"(cellular response to glucose stimulus)|go:"GO:0032091"(negative regulation of protein binding)|go:"GO:0090129"(positive regulation of synapse maturation)|go:"GO:0098794"(postsynapse)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099175"(regulation of postsynapse organization)|go:"GO:1900273"(positive regulation of long-term synaptic potentiation)|go:"GO:1902074"(response to salt)|go:"GO:1902165"(regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator)|go:"GO:1903861"(positive regulation of dendrite extension)|go:"GO:1904322"(cellular response to forskolin)|go:"GO:1905599"(positive regulation of low-density lipoprotein receptor activity)|go:"GO:1990715"(mRNA CDS binding)|go:"GO:1990829"(C-rich single-stranded DNA binding)|go:"GO:2000010"(positive regulation of protein localization to cell surface)|go:"GO:2000173"(negative regulation of branching morphogenesis of a nerve)|interpro:IPR004087(K Homology)|interpro:IPR004088(K Homology, type 1)|interpro:IPR012987(ROK, N-terminal)|interpro:IPR033090|interpro:IPR036612|mint:P61980|reactome:R-RNO-4570464|reactome:R-RNO-72163|go:"GO:0072752"(cellular response to rapamycin)|rgd:71058|refseq:NP_476482.1|refseq:XP_006253616.1	-	-	-	figure legend:st1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10116(rat-hippocampus)|taxid:10116(Rattus norvegicus hippocampal neurons)	-	2020/10/30	2020/10/30	rogid:DtE+ZXAZKdCMvUW5K+jXQ5bH07M10116	rogid:YZQD5JJkHPUMtZ4XUA9fQkNfXzc10116	rigid:zzsc1zNhBb5nwIRPeFpYOKgC3M8	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q5XIE8	uniprotkb:P03994	intact:EBI-15348306|ensembl:ENSRNOP00000023037	intact:EBI-5747169|ensembl:ENSRNOP00000040553|ensembl:ENSRNOP00000045959	psi-mi:itm2b_rat(display_long)|uniprotkb:Itm2b(gene name)|psi-mi:Itm2b(display_short)|uniprotkb:Immature BRI2(gene name synonym)|uniprotkb:Transmembrane protein BRI(gene name synonym)	psi-mi:hpln1_rat(display_long)|uniprotkb:Hapln1(gene name)|psi-mi:Hapln1(display_short)|uniprotkb:Crtl1(gene name synonym)|uniprotkb:Cartilage-linking protein 1(gene name synonym)|uniprotkb:Proteoglycan link protein(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Martins et al. (2018)	imex:IM-28469|pubmed:29476059	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26440627|imex:IM-28469-5	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSRNOG00000016271(gene)|ensembl:ENSRNOT00000023037(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001540"(amyloid-beta binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0010008"(endosome membrane)|go:"GO:0030660"(Golgi-associated vesicle membrane)|go:"GO:0031301"(integral component of organelle membrane)|go:"GO:0042985"(negative regulation of amyloid precursor protein biosynthetic process)|interpro:IPR007084(BRICHOS)|interpro:IPR040145|mint:Q5XIE8|refseq:NP_001006964.1|rgd:620727	rgd:2412|refseq:XP_006231810.1|ensembl:ENSRNOG00000032002(gene)|ensembl:ENSRNOT00000042958(transcript)|ensembl:ENSRNOT00000043196(transcript)|go:"GO:0001501"(skeletal system development)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005540"(hyaluronic acid binding)|go:"GO:0005576"(extracellular region)|go:"GO:0007155"(cell adhesion)|go:"GO:0007417"(central nervous system development)|go:"GO:0031012"(extracellular matrix)|go:"GO:0045202"(synapse)|interpro:IPR000538(Link)|interpro:IPR003599(Immunoglobulin subtype)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR013106(Immunoglobulin V-set)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR016186(C-type lectin-like)|interpro:IPR016187(C-type lectin fold)|interpro:IPR036179|mint:P03994|reactome:R-RNO-3000178	-	-	-	figure legend:st1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10116(rat-hippocampus)|taxid:10116(Rattus norvegicus hippocampal neurons)	-	2020/10/30	2020/10/30	rogid:DtE+ZXAZKdCMvUW5K+jXQ5bH07M10116	rogid:TQ7UE3ZsSgesM1DKbMig4A1kCYQ10116	rigid:zzsc1zNhBb5nwIRPeFpYOKgC3M8	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q5XIE8	uniprotkb:Q6AY09	intact:EBI-15348306|ensembl:ENSRNOP00000023037	intact:EBI-1638443|ensembl:ENSRNOP00000015518	psi-mi:itm2b_rat(display_long)|uniprotkb:Itm2b(gene name)|psi-mi:Itm2b(display_short)|uniprotkb:Immature BRI2(gene name synonym)|uniprotkb:Transmembrane protein BRI(gene name synonym)	psi-mi:hnrh2_rat(display_long)|uniprotkb:Hnrnph2(gene name)|psi-mi:Hnrnph2(display_short)|uniprotkb:Hnrph2(gene name synonym)|uniprotkb:Heterogeneous nuclear ribonucleoprotein H'(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Martins et al. (2018)	imex:IM-28469|pubmed:29476059	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26440627|imex:IM-28469-5	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSRNOG00000016271(gene)|ensembl:ENSRNOT00000023037(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001540"(amyloid-beta binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0010008"(endosome membrane)|go:"GO:0030660"(Golgi-associated vesicle membrane)|go:"GO:0031301"(integral component of organelle membrane)|go:"GO:0042985"(negative regulation of amyloid precursor protein biosynthetic process)|interpro:IPR007084(BRICHOS)|interpro:IPR040145|mint:Q5XIE8|refseq:NP_001006964.1|rgd:620727	rgd:1549784|refseq:NP_001014041.1|refseq:XP_006257281.1|refseq:XP_006257282.1|refseq:XP_006257283.1|ensembl:ENSRNOG00000011661(gene)|ensembl:ENSRNOT00000015518(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0005829"(cytosol)|go:"GO:0014069"(postsynaptic density)|go:"GO:0043484"(regulation of RNA splicing)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR012996(Zinc finger, CHHC-type)|interpro:IPR035979|mint:Q6AY09|reactome:R-RNO-72163|go:"GO:0005654"(nucleoplasm)	-	-	-	figure legend:st1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10116(rat-hippocampus)|taxid:10116(Rattus norvegicus hippocampal neurons)	-	2020/10/30	2020/10/30	rogid:DtE+ZXAZKdCMvUW5K+jXQ5bH07M10116	rogid:iYxEIXbVEciSTaqi1m4uhyPppRE10116	rigid:zzsc1zNhBb5nwIRPeFpYOKgC3M8	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q5XIE8	uniprotkb:P01026	intact:EBI-15348306|ensembl:ENSRNOP00000023037	intact:EBI-6096102|uniprotkb:Q9ET19|uniprotkb:Q9QV57|uniprotkb:Q9QV58	psi-mi:itm2b_rat(display_long)|uniprotkb:Itm2b(gene name)|psi-mi:Itm2b(display_short)|uniprotkb:Immature BRI2(gene name synonym)|uniprotkb:Transmembrane protein BRI(gene name synonym)	psi-mi:co3_rat(display_long)|uniprotkb:C3(gene name)|psi-mi:C3(display_short)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Martins et al. (2018)	imex:IM-28469|pubmed:29476059	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26440627|imex:IM-28469-5	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSRNOG00000016271(gene)|ensembl:ENSRNOT00000023037(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001540"(amyloid-beta binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0010008"(endosome membrane)|go:"GO:0030660"(Golgi-associated vesicle membrane)|go:"GO:0031301"(integral component of organelle membrane)|go:"GO:0042985"(negative regulation of amyloid precursor protein biosynthetic process)|interpro:IPR007084(BRICHOS)|interpro:IPR040145|mint:Q5XIE8|refseq:NP_001006964.1|rgd:620727	mint:P01026|interpro:IPR035711|interpro:IPR035815|interpro:IPR036595|interpro:IPR013783(Immunoglobulin-like fold)|rgd:2232|refseq:NP_058690.2|interpro:IPR009048(Alpha-macroglobulin, receptor-binding)|interpro:IPR011626(A-macroglobulin complement component)|interpro:IPR002890(Alpha-2-macroglobulin, N-terminal)|interpro:IPR011625(Alpha-2-macroglobulin, N-terminal 2)|interpro:IPR000020(Anaphylatoxin/fibulin)|interpro:IPR018081|interpro:IPR001840(Complement C3a/C4a/C5a anaphylatoxin)|interpro:IPR001599(Alpha-2-macroglobulin)|interpro:IPR019742|interpro:IPR001134(Netrin, C-terminal)|interpro:IPR018933|interpro:IPR008930(Terpenoid cylases/protein prenyltransferase alpha-alpha toroid)|interpro:IPR008993(TIMP-like, OB-fold)|interpro:IPR040839|interpro:IPR041425|interpro:IPR041555|go:"GO:0001798"(positive regulation of type IIa hypersensitivity)|go:"GO:0001934"(positive regulation of protein phosphorylation)|go:"GO:0001970"(positive regulation of activation of membrane attack complex)|go:"GO:0002507"(tolerance induction)|go:"GO:0004866"(endopeptidase inhibitor activity)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0006631"(fatty acid metabolic process)|go:"GO:0006935"(chemotaxis)|go:"GO:0006954"(inflammatory response)|go:"GO:0006956"(complement activation)|go:"GO:0006957"(complement activation, alternative pathway)|go:"GO:0006958"(complement activation, classical pathway)|go:"GO:0007596"(blood coagulation)|go:"GO:0008289"(lipid binding)|go:"GO:0009617"(response to bacterium)|go:"GO:0009986"(cell surface)|go:"GO:0010575"(positive regulation of vascular endothelial growth factor production)|go:"GO:0010828"(positive regulation of glucose transmembrane transport)|go:"GO:0010866"(regulation of triglyceride biosynthetic process)|go:"GO:0010884"(positive regulation of lipid storage)|go:"GO:0016322"(neuron remodeling)|go:"GO:0031715"(C5L2 anaphylatoxin chemotactic receptor binding)|go:"GO:0032026"(response to magnesium ion)|go:"GO:0032355"(response to estradiol)|go:"GO:0032570"(response to progesterone)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035846"(oviduct epithelium development)|go:"GO:0035886"(vascular associated smooth muscle cell differentiation)|go:"GO:0043627"(response to estrogen)|go:"GO:0045745"(positive regulation of G protein-coupled receptor signaling pathway)|go:"GO:0045766"(positive regulation of angiogenesis)|go:"GO:0048260"(positive regulation of receptor-mediated endocytosis)|go:"GO:0048639"(positive regulation of developmental growth)|go:"GO:0050766"(positive regulation of phagocytosis)|go:"GO:0051384"(response to glucocorticoid)|go:"GO:0060041"(retina development in camera-type eye)|go:"GO:0060100"(positive regulation of phagocytosis, engulfment)|go:"GO:0070374"(positive regulation of ERK1 and ERK2 cascade)|go:"GO:0097242"(amyloid-beta clearance)|go:"GO:0097278"(complement-dependent cytotoxicity)|go:"GO:0150062"(complement-mediated synapse pruning)|go:"GO:0150064"(vertebrate eye-specific patterning)|go:"GO:1901555"(response to paclitaxel)|go:"GO:1905114"(cell surface receptor signaling pathway involved in cell-cell signaling)|go:"GO:2000427"(positive regulation of apoptotic cell clearance)|rcsb pdb:1QQF|rcsb pdb:1QSJ|reactome:R-RNO-173736|reactome:R-RNO-174577|reactome:R-RNO-198933|reactome:R-RNO-375276|reactome:R-RNO-381426|reactome:R-RNO-418594|reactome:R-RNO-6798695|reactome:R-RNO-8957275|reactome:R-RNO-977606	-	-	-	figure legend:st1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10116(rat-hippocampus)|taxid:10116(Rattus norvegicus hippocampal neurons)	-	2020/10/30	2020/10/30	rogid:DtE+ZXAZKdCMvUW5K+jXQ5bH07M10116	rogid:7yW59Wpi5Yq8jY85OvBPgOqOMAc10116	rigid:zzsc1zNhBb5nwIRPeFpYOKgC3M8	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q5XIE8	uniprotkb:Q3KRE8	intact:EBI-15348306|ensembl:ENSRNOP00000023037	intact:EBI-349199|ensembl:ENSRNOP00000023582|ensembl:ENSRNOP00000073323|uniprotkb:A3KMR7|uniprotkb:P04691	psi-mi:itm2b_rat(display_long)|uniprotkb:Itm2b(gene name)|psi-mi:Itm2b(display_short)|uniprotkb:Immature BRI2(gene name synonym)|uniprotkb:Transmembrane protein BRI(gene name synonym)	psi-mi:tbb2b_rat(display_long)|uniprotkb:T beta-15(gene name synonym)|uniprotkb:Tubb2b(gene name)|psi-mi:Tubb2b(display_short)|uniprotkb:Tubb2a(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Martins et al. (2018)	imex:IM-28469|pubmed:29476059	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26440627|imex:IM-28469-5	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSRNOG00000016271(gene)|ensembl:ENSRNOT00000023037(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001540"(amyloid-beta binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0010008"(endosome membrane)|go:"GO:0030660"(Golgi-associated vesicle membrane)|go:"GO:0031301"(integral component of organelle membrane)|go:"GO:0042985"(negative regulation of amyloid precursor protein biosynthetic process)|interpro:IPR007084(BRICHOS)|interpro:IPR040145|mint:Q5XIE8|refseq:NP_001006964.1|rgd:620727	rgd:1309427|refseq:NP_001013908.2|ensembl:ENSRNOG00000017445(gene)|ensembl:ENSRNOT00000023582(transcript)|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0001764"(neuron migration)|go:"GO:0005200"(structural constituent of cytoskeleton)|go:"GO:0005525"(GTP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005874"(microtubule)|go:"GO:0007017"(microtubule-based process)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0050804"(modulation of chemical synaptic transmission)|go:"GO:0098685"(Schaffer collateral - CA1 synapse)|go:"GO:1902669"(positive regulation of axon guidance)|go:"GO:1990403"(embryonic brain development)|interpro:IPR000217(Tubulin)|interpro:IPR002453(Beta tubulin)|interpro:IPR003008(Tubulin/FtsZ, GTPase)|interpro:IPR008280(Tubulin/FtsZ, C-terminal)|interpro:IPR013838(Beta tubulin, autoregulation binding site)|ensembl:ENSRNOT00000083705(transcript)|reactome:R-RNO-5626467|interpro:IPR017975|interpro:IPR018316|reactome:R-RNO-5663220|reactome:R-RNO-6807878|reactome:R-RNO-6811434|interpro:IPR023123|reactome:R-RNO-6811436|reactome:R-RNO-68877|reactome:R-RNO-8852276|reactome:R-RNO-8955332|interpro:IPR036525|interpro:IPR037103|mint:Q3KRE8|reactome:R-RNO-190840|reactome:R-RNO-9646399|reactome:R-RNO-9648025|reactome:R-RNO-9668328|reactome:R-RNO-2132295|reactome:R-RNO-2467813|reactome:R-RNO-2500257|reactome:R-RNO-3371497|reactome:R-RNO-380320|reactome:R-RNO-437239|reactome:R-RNO-5610787|reactome:R-RNO-5617833|reactome:R-RNO-5620924|reactome:R-RNO-983189	-	-	-	figure legend:st1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10116(rat-hippocampus)|taxid:10116(Rattus norvegicus hippocampal neurons)	-	2020/10/30	2020/10/30	rogid:DtE+ZXAZKdCMvUW5K+jXQ5bH07M10116	rogid:sluQMryNuOvp6xlV558+agiRwvE10116	rigid:zzsc1zNhBb5nwIRPeFpYOKgC3M8	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q5XIE8	uniprotkb:Q6P7B0	intact:EBI-15348306|ensembl:ENSRNOP00000023037	intact:EBI-16221697|ensembl:ENSRNOP00000006128	psi-mi:itm2b_rat(display_long)|uniprotkb:Itm2b(gene name)|psi-mi:Itm2b(display_short)|uniprotkb:Immature BRI2(gene name synonym)|uniprotkb:Transmembrane protein BRI(gene name synonym)	psi-mi:sywc_rat(display_long)|uniprotkb:Wars1(gene name)|psi-mi:Wars1(display_short)|uniprotkb:Tryptophanyl-tRNA synthetase(gene name synonym)|uniprotkb:Wars(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Martins et al. (2018)	imex:IM-28469|pubmed:29476059	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26440627|imex:IM-28469-5	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSRNOG00000016271(gene)|ensembl:ENSRNOT00000023037(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001540"(amyloid-beta binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0010008"(endosome membrane)|go:"GO:0030660"(Golgi-associated vesicle membrane)|go:"GO:0031301"(integral component of organelle membrane)|go:"GO:0042985"(negative regulation of amyloid precursor protein biosynthetic process)|interpro:IPR007084(BRICHOS)|interpro:IPR040145|mint:Q5XIE8|refseq:NP_001006964.1|rgd:620727	ensembl:ENSRNOG00000004359(gene)|ensembl:ENSRNOT00000006128(transcript)|go:"GO:0001525"(angiogenesis)|go:"GO:0001933"(negative regulation of protein phosphorylation)|go:"GO:0004830"(tryptophan-tRNA ligase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006436"(tryptophanyl-tRNA aminoacylation)|go:"GO:0006469"(negative regulation of protein kinase activity)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010835"(regulation of protein ADP-ribosylation)|go:"GO:0019210"(kinase inhibitor activity)|go:"GO:0019901"(protein kinase binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0031334"(positive regulation of protein-containing complex assembly)|go:"GO:0032991"(protein-containing complex)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0045765"(regulation of angiogenesis)|interpro:IPR000738(WHEP-TRS)|interpro:IPR001412(Aminoacyl-tRNA synthetase, class I, conserved site)|interpro:IPR002305(Aminoacyl-tRNA synthetase, class Ib)|interpro:IPR002306(Tryptophanyl-tRNA synthetase, class Ib)|interpro:IPR009068(S15/NS1, RNA-binding)|interpro:IPR014729(Rossmann-like alpha/beta/alpha sandwich fold)|mint:Q6P7B0|refseq:XP_006240604.1|refseq:XP_008763034.1|rgd:1308278	-	-	-	figure legend:st1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10116(rat-hippocampus)|taxid:10116(Rattus norvegicus hippocampal neurons)	-	2020/10/30	2020/10/30	rogid:DtE+ZXAZKdCMvUW5K+jXQ5bH07M10116	rogid:wDEyHrQQZA/Jbz9CWIIcusLZXxE10116	rigid:zzsc1zNhBb5nwIRPeFpYOKgC3M8	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q5XIE8	uniprotkb:P61765	intact:EBI-15348306|ensembl:ENSRNOP00000023037	intact:EBI-1029097|uniprotkb:Q28208|uniprotkb:Q62759|uniprotkb:Q64320|uniprotkb:Q96TG8|ensembl:ENSRNOP00000021178	psi-mi:itm2b_rat(display_long)|uniprotkb:Itm2b(gene name)|psi-mi:Itm2b(display_short)|uniprotkb:Immature BRI2(gene name synonym)|uniprotkb:Transmembrane protein BRI(gene name synonym)	psi-mi:stxb1_rat(display_long)|uniprotkb:Stxbp1(gene name)|psi-mi:Stxbp1(display_short)|uniprotkb:Unc18a(gene name synonym)|uniprotkb:Protein unc-18 homolog 1(gene name synonym)|uniprotkb:Protein unc-18 homolog A(gene name synonym)|uniprotkb:N-Sec1(gene name synonym)|uniprotkb:rbSec1(gene name synonym)|uniprotkb:p67(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Martins et al. (2018)	imex:IM-28469|pubmed:29476059	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26440627|imex:IM-28469-5	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSRNOG00000016271(gene)|ensembl:ENSRNOT00000023037(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001540"(amyloid-beta binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0010008"(endosome membrane)|go:"GO:0030660"(Golgi-associated vesicle membrane)|go:"GO:0031301"(integral component of organelle membrane)|go:"GO:0042985"(negative regulation of amyloid precursor protein biosynthetic process)|interpro:IPR007084(BRICHOS)|interpro:IPR040145|mint:Q5XIE8|refseq:NP_001006964.1|rgd:620727	rgd:3785|refseq:NP_037170.1|ensembl:ENSRNOG00000015420(gene)|ensembl:ENSRNOT00000021178(transcript)|go:"GO:0000149"(SNARE binding)|go:"GO:0002576"(platelet degranulation)|go:"GO:0003006"(developmental process involved in reproduction)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005886"(plasma membrane)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006887"(exocytosis)|go:"GO:0006904"(vesicle docking involved in exocytosis)|go:"GO:0007269"(neurotransmitter secretion)|go:"GO:0007274"(neuromuscular synaptic transmission)|go:"GO:0007412"(axon target recognition)|go:"GO:0010807"(regulation of synaptic vesicle priming)|go:"GO:0016082"(synaptic vesicle priming)|go:"GO:0016188"(synaptic vesicle maturation)|go:"GO:0016192"(vesicle-mediated transport)|go:"GO:0017075"(syntaxin-1 binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0019905"(syntaxin binding)|go:"GO:0030141"(secretory granule)|go:"GO:0030424"(axon)|go:"GO:0031091"(platelet alpha granule)|go:"GO:0031333"(negative regulation of protein-containing complex assembly)|go:"GO:0031338"(regulation of vesicle fusion)|go:"GO:0032355"(response to estradiol)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035493"(SNARE complex assembly)|go:"GO:0035544"(negative regulation of SNARE complex assembly)|go:"GO:0042802"(identical protein binding)|go:"GO:0043195"(terminal bouton)|go:"GO:0043274"(phospholipase binding)|go:"GO:0043306"(positive regulation of mast cell degranulation)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0045335"(phagocytic vesicle)|go:"GO:0045921"(positive regulation of exocytosis)|go:"GO:0045956"(positive regulation of calcium ion-dependent exocytosis)|go:"GO:0047485"(protein N-terminus binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0048787"(presynaptic active zone membrane)|go:"GO:0050821"(protein stabilization)|go:"GO:0060292"(long-term synaptic depression)|go:"GO:0070527"(platelet aggregation)|go:"GO:0071346"(cellular response to interferon-gamma)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0098793"(presynapse)|go:"GO:0098794"(postsynapse)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099525"(presynaptic dense core vesicle exocytosis)|go:"GO:0106022"(positive regulation of vesicle docking)|go:"GO:1903296"(positive regulation of glutamate secretion, neurotransmission)|go:"GO:2000367"(regulation of acrosomal vesicle exocytosis)|interpro:IPR001619(Sec1-like protein)|interpro:IPR027482|interpro:IPR036045|interpro:IPR043127|interpro:IPR043154|mint:P61765|rcsb pdb:3C98|rcsb pdb:3PUJ|rcsb pdb:4JEH|rcsb pdb:4JEU|rcsb pdb:6LPC|reactome:R-RNO-181429|reactome:R-RNO-181430|reactome:R-RNO-210500|reactome:R-RNO-212676|reactome:R-RNO-264642|reactome:R-RNO-888590|go:"GO:0032229"(negative regulation of synaptic transmission, GABAergic)|refseq:XP_006234001.1|dip:DIP-766N	-	-	-	figure legend:st1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10116(rat-hippocampus)|taxid:10116(Rattus norvegicus hippocampal neurons)	-	2020/10/30	2020/10/30	rogid:DtE+ZXAZKdCMvUW5K+jXQ5bH07M10116	rogid:yUYi89hDkfMdQ1BdH52swZQFCLk10116	rigid:zzsc1zNhBb5nwIRPeFpYOKgC3M8	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q5XIE8	uniprotkb:P07825	intact:EBI-15348306|ensembl:ENSRNOP00000023037	intact:EBI-976085|uniprotkb:Q499R3	psi-mi:itm2b_rat(display_long)|uniprotkb:Itm2b(gene name)|psi-mi:Itm2b(display_short)|uniprotkb:Immature BRI2(gene name synonym)|uniprotkb:Transmembrane protein BRI(gene name synonym)	psi-mi:syph_rat(display_long)|uniprotkb:Major synaptic vesicle protein p38(gene name synonym)|uniprotkb:Syp(gene name)|psi-mi:Syp(display_short)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Martins et al. (2018)	imex:IM-28469|pubmed:29476059	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26440627|imex:IM-28469-5	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSRNOG00000016271(gene)|ensembl:ENSRNOT00000023037(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001540"(amyloid-beta binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0010008"(endosome membrane)|go:"GO:0030660"(Golgi-associated vesicle membrane)|go:"GO:0031301"(integral component of organelle membrane)|go:"GO:0042985"(negative regulation of amyloid precursor protein biosynthetic process)|interpro:IPR007084(BRICHOS)|interpro:IPR040145|mint:Q5XIE8|refseq:NP_001006964.1|rgd:620727	go:"GO:0030285"(integral component of synaptic vesicle membrane)|go:"GO:0048169"(regulation of long-term neuronal synaptic plasticity)|go:"GO:0030672"(synaptic vesicle membrane)|go:"GO:0048172"(regulation of short-term neuronal synaptic plasticity)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0031594"(neuromuscular junction)|go:"GO:0048488"(synaptic vesicle endocytosis)|go:"GO:0048786"(presynaptic active zone)|go:"GO:0060076"(excitatory synapse)|go:"GO:0032991"(protein-containing complex)|go:"GO:0071310"(cellular response to organic substance)|go:"GO:0042169"(SH2 domain binding)|go:"GO:0098685"(Schaffer collateral - CA1 synapse)|go:"GO:0042734"(presynaptic membrane)|go:"GO:1904645"(response to amyloid-beta)|go:"GO:2000300"(regulation of synaptic vesicle exocytosis)|go:"GO:0042802"(identical protein binding)|go:"GO:0043005"(neuron projection)|go:"GO:0043195"(terminal bouton)|go:"GO:2000474"(regulation of opioid receptor signaling pathway)|go:"GO:0043229"(intracellular organelle)|go:"GO:0044306"(neuron projection terminus)|go:"GO:0044309"(neuron spine)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045202"(synapse)|go:"GO:0048168"(regulation of neuronal synaptic plasticity)|go:"GO:0000149"(SNARE binding)|go:"GO:0006897"(endocytosis)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0014069"(postsynaptic density)|go:"GO:0015485"(cholesterol binding)|go:"GO:0016020"(membrane)|go:"GO:0017075"(syntaxin-1 binding)|go:"GO:0019904"(protein domain specific binding)|rgd:3802|refseq:NP_036796.1|interpro:IPR008253(Marvel)|interpro:IPR001285(Synaptophysin/synaptoporin)|interpro:IPR028714|mint:P07825	-	-	-	figure legend:st1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10116(rat-hippocampus)|taxid:10116(Rattus norvegicus hippocampal neurons)	-	2020/10/30	2020/10/30	rogid:DtE+ZXAZKdCMvUW5K+jXQ5bH07M10116	rogid:nG9lA5IrA7dLVQ2QlJ7VhtruLLg10116	rigid:zzsc1zNhBb5nwIRPeFpYOKgC3M8	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q5XIE8	uniprotkb:Q63564	intact:EBI-15348306|ensembl:ENSRNOP00000023037	intact:EBI-9254006	psi-mi:itm2b_rat(display_long)|uniprotkb:Itm2b(gene name)|psi-mi:Itm2b(display_short)|uniprotkb:Immature BRI2(gene name synonym)|uniprotkb:Transmembrane protein BRI(gene name synonym)	psi-mi:sv2b_rat(display_long)|uniprotkb:Sv2b(gene name)|psi-mi:Sv2b(display_short)|uniprotkb:Sv2bb(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Martins et al. (2018)	imex:IM-28469|pubmed:29476059	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26440627|imex:IM-28469-5	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSRNOG00000016271(gene)|ensembl:ENSRNOT00000023037(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001540"(amyloid-beta binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0010008"(endosome membrane)|go:"GO:0030660"(Golgi-associated vesicle membrane)|go:"GO:0031301"(integral component of organelle membrane)|go:"GO:0042985"(negative regulation of amyloid precursor protein biosynthetic process)|interpro:IPR007084(BRICHOS)|interpro:IPR040145|mint:Q5XIE8|refseq:NP_001006964.1|rgd:620727	interpro:IPR011701(Major facilitator superfamily MFS-1)|interpro:IPR020846|interpro:IPR005828(General substrate transporter)|interpro:IPR005829(Sugar transporter, conserved site)|interpro:IPR022308|mint:Q63564|rgd:619716|refseq:NP_476555.1|interpro:IPR036259|go:"GO:0001504"(neurotransmitter uptake)|go:"GO:0001669"(acrosomal vesicle)|go:"GO:0007268"(chemical synaptic transmission)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0022857"(transmembrane transporter activity)|go:"GO:0030285"(integral component of synaptic vesicle membrane)|go:"GO:0030672"(synaptic vesicle membrane)|go:"GO:0043005"(neuron projection)|go:"GO:0043195"(terminal bouton)	-	-	-	figure legend:st1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10116(rat-hippocampus)|taxid:10116(Rattus norvegicus hippocampal neurons)	-	2020/10/30	2020/10/30	rogid:DtE+ZXAZKdCMvUW5K+jXQ5bH07M10116	rogid:PnkAiRP4l+Bkf3cK1gDGTPCsT/810116	rigid:zzsc1zNhBb5nwIRPeFpYOKgC3M8	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q5XIE8	uniprotkb:P09951	intact:EBI-15348306|ensembl:ENSRNOP00000023037	intact:EBI-1638487|uniprotkb:Q9WUX7|ensembl:ENSRNOP00000014250	psi-mi:itm2b_rat(display_long)|uniprotkb:Itm2b(gene name)|psi-mi:Itm2b(display_short)|uniprotkb:Immature BRI2(gene name synonym)|uniprotkb:Transmembrane protein BRI(gene name synonym)	psi-mi:syn1_rat(display_long)|uniprotkb:Syn1(gene name)|psi-mi:Syn1(display_short)|uniprotkb:Synapsin I(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Martins et al. (2018)	imex:IM-28469|pubmed:29476059	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26440627|imex:IM-28469-5	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSRNOG00000016271(gene)|ensembl:ENSRNOT00000023037(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001540"(amyloid-beta binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0010008"(endosome membrane)|go:"GO:0030660"(Golgi-associated vesicle membrane)|go:"GO:0031301"(integral component of organelle membrane)|go:"GO:0042985"(negative regulation of amyloid precursor protein biosynthetic process)|interpro:IPR007084(BRICHOS)|interpro:IPR040145|mint:Q5XIE8|refseq:NP_001006964.1|rgd:620727	rgd:3797|refseq:NP_001104252.1|refseq:NP_062006.1|ensembl:ENSRNOG00000010365(gene)|ensembl:ENSRNOT00000014250(transcript)|go:"GO:0000795"(synaptonemal complex)|go:"GO:0003779"(actin binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0007269"(neurotransmitter secretion)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0014069"(postsynaptic density)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030424"(axon)|go:"GO:0030425"(dendrite)|go:"GO:0030672"(synaptic vesicle membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0043195"(terminal bouton)|go:"GO:0043229"(intracellular organelle)|go:"GO:0045202"(synapse)|go:"GO:0048306"(calcium-dependent protein binding)|go:"GO:0048666"(neuron development)|go:"GO:0048786"(presynaptic active zone)|go:"GO:0050808"(synapse organization)|go:"GO:0097091"(synaptic vesicle clustering)|go:"GO:0098685"(Schaffer collateral - CA1 synapse)|go:"GO:0098693"(regulation of synaptic vesicle cycle)|go:"GO:0098793"(presynapse)|go:"GO:0098850"(extrinsic component of synaptic vesicle membrane)|go:"GO:0098993"(anchored component of synaptic vesicle membrane)|go:"GO:0099504"(synaptic vesicle cycle)|interpro:IPR001359(Synapsin)|interpro:IPR013815(ATP-grasp fold, subdomain 1)|interpro:IPR016185(PreATP-grasp-like fold)|interpro:IPR019735|interpro:IPR019736|interpro:IPR020897|interpro:IPR020898|interpro:IPR028713|mint:P09951|rcsb pdb:1PK8|rcsb pdb:1PX2|reactome:R-RNO-181429|reactome:R-RNO-212676	-	-	-	figure legend:st1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10116(rat-hippocampus)|taxid:10116(Rattus norvegicus hippocampal neurons)	-	2020/10/30	2020/10/30	rogid:DtE+ZXAZKdCMvUW5K+jXQ5bH07M10116	rogid:2Kokx9XJDZPkBHu140QPqsDpSxw10116	rigid:zzsc1zNhBb5nwIRPeFpYOKgC3M8	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q5XIE8	uniprotkb:Q63965	intact:EBI-15348306|ensembl:ENSRNOP00000023037	intact:EBI-918690	psi-mi:itm2b_rat(display_long)|uniprotkb:Itm2b(gene name)|psi-mi:Itm2b(display_short)|uniprotkb:Immature BRI2(gene name synonym)|uniprotkb:Transmembrane protein BRI(gene name synonym)	psi-mi:sfxn1_rat(display_long)|uniprotkb:Tricarboxylate carrier protein(gene name synonym)|uniprotkb:Sfxn1(gene name)|psi-mi:Sfxn1(display_short)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Martins et al. (2018)	imex:IM-28469|pubmed:29476059	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26440627|imex:IM-28469-5	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSRNOG00000016271(gene)|ensembl:ENSRNOT00000023037(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001540"(amyloid-beta binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0010008"(endosome membrane)|go:"GO:0030660"(Golgi-associated vesicle membrane)|go:"GO:0031301"(integral component of organelle membrane)|go:"GO:0042985"(negative regulation of amyloid precursor protein biosynthetic process)|interpro:IPR007084(BRICHOS)|interpro:IPR040145|mint:Q5XIE8|refseq:NP_001006964.1|rgd:620727	interpro:IPR004686(Tricarboxylate/iron carrier)|rgd:1308482|mint:Q63965|go:"GO:0005739"(mitochondrion)|go:"GO:0006730"(one-carbon metabolic process)|go:"GO:0006826"(iron ion transport)|go:"GO:0015194"(L-serine transmembrane transporter activity)|go:"GO:0015825"(L-serine transport)|go:"GO:0022857"(transmembrane transporter activity)|go:"GO:0022889"(serine transmembrane transporter activity)|go:"GO:0030218"(erythrocyte differentiation)|go:"GO:0031305"(integral component of mitochondrial inner membrane)|go:"GO:0042942"(D-serine transport)|go:"GO:0042945"(D-serine transmembrane transporter activity)|go:"GO:0140300"(serine import into mitochondrion)|go:"GO:1990542"(mitochondrial transmembrane transport)	-	-	-	figure legend:st1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10116(rat-hippocampus)|taxid:10116(Rattus norvegicus hippocampal neurons)	-	2020/10/30	2020/10/30	rogid:DtE+ZXAZKdCMvUW5K+jXQ5bH07M10116	rogid:oy+pnAKs08HtNyA+d5es2yVFgPY10116	rigid:zzsc1zNhBb5nwIRPeFpYOKgC3M8	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q5XIE8	uniprotkb:O08875	intact:EBI-15348306|ensembl:ENSRNOP00000023037	intact:EBI-26439688|ensembl:ENSRNOP00000019748	psi-mi:itm2b_rat(display_long)|uniprotkb:Itm2b(gene name)|psi-mi:Itm2b(display_short)|uniprotkb:Immature BRI2(gene name synonym)|uniprotkb:Transmembrane protein BRI(gene name synonym)	psi-mi:dclk1_rat(display_long)|uniprotkb:Dclk1(gene name)|psi-mi:Dclk1(display_short)|uniprotkb:Cpg16(gene name synonym)|uniprotkb:Dcamkl1(gene name synonym)|uniprotkb:Calcium/calmodulin-dependent protein kinase type I-like CPG16(gene name synonym)|uniprotkb:Doublecortin-like and CAM kinase-like 1(gene name synonym)|uniprotkb:Doublecortin-like kinase 1(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Martins et al. (2018)	imex:IM-28469|pubmed:29476059	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26440627|imex:IM-28469-5	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSRNOG00000016271(gene)|ensembl:ENSRNOT00000023037(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001540"(amyloid-beta binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0010008"(endosome membrane)|go:"GO:0030660"(Golgi-associated vesicle membrane)|go:"GO:0031301"(integral component of organelle membrane)|go:"GO:0042985"(negative regulation of amyloid precursor protein biosynthetic process)|interpro:IPR007084(BRICHOS)|interpro:IPR040145|mint:Q5XIE8|refseq:NP_001006964.1|rgd:620727	ensembl:ENSRNOG00000032922(gene)|ensembl:ENSRNOT00000019748(transcript)|go:"GO:0001764"(neuron migration)|go:"GO:0004672"(protein kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0007409"(axonogenesis)|go:"GO:0007420"(brain development)|go:"GO:0009615"(response to virus)|go:"GO:0014069"(postsynaptic density)|go:"GO:0018105"(peptidyl-serine phosphorylation)|go:"GO:0021952"(central nervous system projection neuron axonogenesis)|go:"GO:0030424"(axon)|go:"GO:0030426"(growth cone)|go:"GO:0030900"(forebrain development)|go:"GO:0048675"(axon extension)|go:"GO:0048812"(neuron projection morphogenesis)|go:"GO:0048813"(dendrite morphogenesis)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:1900181"(negative regulation of protein localization to nucleus)|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|mint:O08875|refseq:NP_445795.1|rgd:68437	-	-	-	figure legend:st1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10116(rat-hippocampus)|taxid:10116(Rattus norvegicus hippocampal neurons)	-	2020/10/30	2020/10/30	rogid:DtE+ZXAZKdCMvUW5K+jXQ5bH07M10116	rogid:Al+f+qhV/hs3YZhZv7GEdSNfDQM10116	rigid:zzsc1zNhBb5nwIRPeFpYOKgC3M8	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q5XIE8	uniprotkb:Q9JJM9	intact:EBI-15348306|ensembl:ENSRNOP00000023037	intact:EBI-539712|uniprotkb:Q8R2F7|uniprotkb:Q9JJM8	psi-mi:itm2b_rat(display_long)|uniprotkb:Itm2b(gene name)|psi-mi:Itm2b(display_short)|uniprotkb:Immature BRI2(gene name synonym)|uniprotkb:Transmembrane protein BRI(gene name synonym)	psi-mi:sept5_rat(display_long)|uniprotkb:Septin5(gene name)|psi-mi:Septin5(display_short)|uniprotkb:Cell division control-related protein 1(gene name synonym)|uniprotkb:Peanut-like protein 1(gene name synonym)|uniprotkb:Pnutl1(gene name synonym)|uniprotkb:Sept5(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Martins et al. (2018)	imex:IM-28469|pubmed:29476059	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26440627|imex:IM-28469-5	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSRNOG00000016271(gene)|ensembl:ENSRNOT00000023037(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001540"(amyloid-beta binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0010008"(endosome membrane)|go:"GO:0030660"(Golgi-associated vesicle membrane)|go:"GO:0031301"(integral component of organelle membrane)|go:"GO:0042985"(negative regulation of amyloid precursor protein biosynthetic process)|interpro:IPR007084(BRICHOS)|interpro:IPR040145|mint:Q5XIE8|refseq:NP_001006964.1|rgd:620727	interpro:IPR027417|interpro:IPR030647|interpro:IPR030379|rgd:621763|interpro:IPR016491(Septin)|mint:Q9JJM9|go:"GO:0005940"(septin ring)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0017157"(regulation of exocytosis)|go:"GO:0005938"(cell cortex)|go:"GO:0019003"(GDP binding)|go:"GO:0019905"(syntaxin binding)|go:"GO:0030534"(adult behavior)|go:"GO:0031105"(septin complex)|go:"GO:0032153"(cell division site)|go:"GO:0032154"(cleavage furrow)|go:"GO:0034613"(cellular protein localization)|go:"GO:0035091"(phosphatidylinositol binding)|go:"GO:0035176"(social behavior)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043195"(terminal bouton)|go:"GO:0043679"(axon terminus)|go:"GO:0044305"(calyx of Held)|go:"GO:0045202"(synapse)|go:"GO:0045921"(positive regulation of exocytosis)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0061640"(cytoskeleton-dependent cytokinesis)|go:"GO:0098793"(presynapse)|go:"GO:0099148"(regulation of synaptic vesicle docking)|go:"GO:0001725"(stress fiber)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005886"(plasma membrane)	-	-	-	figure legend:st1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10116(rat-hippocampus)|taxid:10116(Rattus norvegicus hippocampal neurons)	-	2020/10/30	2020/10/30	rogid:DtE+ZXAZKdCMvUW5K+jXQ5bH07M10116	rogid:bgzs8rx9e+Yn5zYxczLQYJ11i9g10116	rigid:zzsc1zNhBb5nwIRPeFpYOKgC3M8	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q5XIE8	uniprotkb:Q3B7K9	intact:EBI-15348306|ensembl:ENSRNOP00000023037	intact:EBI-26439678|ensembl:ENSRNOP00000035622	psi-mi:itm2b_rat(display_long)|uniprotkb:Itm2b(gene name)|psi-mi:Itm2b(display_short)|uniprotkb:Immature BRI2(gene name synonym)|uniprotkb:Transmembrane protein BRI(gene name synonym)	psi-mi:run3b_rat(display_long)|uniprotkb:Rundc3b(gene name)|psi-mi:Rundc3b(display_short)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Martins et al. (2018)	imex:IM-28469|pubmed:29476059	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26440627|imex:IM-28469-5	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSRNOG00000016271(gene)|ensembl:ENSRNOT00000023037(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001540"(amyloid-beta binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0010008"(endosome membrane)|go:"GO:0030660"(Golgi-associated vesicle membrane)|go:"GO:0031301"(integral component of organelle membrane)|go:"GO:0042985"(negative regulation of amyloid precursor protein biosynthetic process)|interpro:IPR007084(BRICHOS)|interpro:IPR040145|mint:Q5XIE8|refseq:NP_001006964.1|rgd:620727	ensembl:ENSRNOG00000008463(gene)|ensembl:ENSRNOT00000030224(transcript)|interpro:IPR004012(RUN)|interpro:IPR037213|mint:Q3B7K9|refseq:NP_001040581.1|rgd:1587590	-	-	-	figure legend:st1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10116(rat-hippocampus)|taxid:10116(Rattus norvegicus hippocampal neurons)	-	2020/10/30	2020/10/30	rogid:DtE+ZXAZKdCMvUW5K+jXQ5bH07M10116	rogid:mRwxzxsso8OBQr9Y10RTN3nHF4Q10116	rigid:zzsc1zNhBb5nwIRPeFpYOKgC3M8	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q5XIE8	uniprotkb:Q6AXX6	intact:EBI-15348306|ensembl:ENSRNOP00000023037	intact:EBI-15185964|ensembl:ENSRNOP00000014819|uniprotkb:P85300	psi-mi:itm2b_rat(display_long)|uniprotkb:Itm2b(gene name)|psi-mi:Itm2b(display_short)|uniprotkb:Immature BRI2(gene name synonym)|uniprotkb:Transmembrane protein BRI(gene name synonym)	psi-mi:pxl2a_rat(display_long)|uniprotkb:Prxl2a(gene name)|psi-mi:Prxl2a(display_short)|uniprotkb:Fam213a(gene name synonym)|uniprotkb:Pamm(gene name synonym)|uniprotkb:Peroxiredoxin-like 2 activated in M-CSF stimulated monocytes(gene name synonym)|uniprotkb:Shp1(gene name synonym)|uniprotkb:Sperm head protein 1(gene name synonym)|uniprotkb:Redox-regulatory protein FAM213A(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Martins et al. (2018)	imex:IM-28469|pubmed:29476059	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26440627|imex:IM-28469-5	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSRNOG00000016271(gene)|ensembl:ENSRNOT00000023037(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001540"(amyloid-beta binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0010008"(endosome membrane)|go:"GO:0030660"(Golgi-associated vesicle membrane)|go:"GO:0031301"(integral component of organelle membrane)|go:"GO:0042985"(negative regulation of amyloid precursor protein biosynthetic process)|interpro:IPR007084(BRICHOS)|interpro:IPR040145|mint:Q5XIE8|refseq:NP_001006964.1|rgd:620727	ensembl:ENSRNOG00000011140(gene)|ensembl:ENSRNOT00000014819(transcript)|go:"GO:0005576"(extracellular region)|go:"GO:0005737"(cytoplasm)|go:"GO:0016209"(antioxidant activity)|interpro:IPR032801|interpro:IPR032802|interpro:IPR036249|mint:Q6AXX6|go:"GO:0045670"(regulation of osteoclast differentiation)|refseq:NP_001014162.1|refseq:XP_006252853.1|rgd:1309676	-	-	-	figure legend:st1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10116(rat-hippocampus)|taxid:10116(Rattus norvegicus hippocampal neurons)	-	2020/10/30	2020/10/30	rogid:DtE+ZXAZKdCMvUW5K+jXQ5bH07M10116	rogid:Tnbl3GNIUDyvJ64sU2mgQxM/llc10116	rigid:zzsc1zNhBb5nwIRPeFpYOKgC3M8	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q5XIE8	uniprotkb:P62824	intact:EBI-15348306|ensembl:ENSRNOP00000023037	intact:EBI-16220903|ensembl:ENSRNOP00000015871|ensembl:ENSRNOP00000073277|uniprotkb:Q62858|uniprotkb:Q62974|uniprotkb:Q63482|uniprotkb:Q9CXQ1	psi-mi:itm2b_rat(display_long)|uniprotkb:Itm2b(gene name)|psi-mi:Itm2b(display_short)|uniprotkb:Immature BRI2(gene name synonym)|uniprotkb:Transmembrane protein BRI(gene name synonym)	psi-mi:rab3c_rat(display_long)|uniprotkb:Rab3c(gene name)|psi-mi:Rab3c(display_short)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Martins et al. (2018)	imex:IM-28469|pubmed:29476059	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26440627|imex:IM-28469-5	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSRNOG00000016271(gene)|ensembl:ENSRNOT00000023037(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001540"(amyloid-beta binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0010008"(endosome membrane)|go:"GO:0030660"(Golgi-associated vesicle membrane)|go:"GO:0031301"(integral component of organelle membrane)|go:"GO:0042985"(negative regulation of amyloid precursor protein biosynthetic process)|interpro:IPR007084(BRICHOS)|interpro:IPR040145|mint:Q5XIE8|refseq:NP_001006964.1|rgd:620727	ensembl:ENSRNOG00000011623(gene)|ensembl:ENSRNOT00000015871(transcript)|ensembl:ENSRNOT00000086851(transcript)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005768"(endosome)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006904"(vesicle docking involved in exocytosis)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0009306"(protein secretion)|go:"GO:0017157"(regulation of exocytosis)|go:"GO:0019882"(antigen processing and presentation)|go:"GO:0030742"(GTP-dependent protein binding)|go:"GO:0031489"(myosin V binding)|go:"GO:0031982"(vesicle)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0098993"(anchored component of synaptic vesicle membrane)|interpro:IPR001806(Ras GTPase)|interpro:IPR005225(Small GTP-binding protein)|interpro:IPR027417|interpro:IPR037872|mint:P62824|reactome:R-RNO-8873719|refseq:NP_598220.1|rgd:620923	-	-	-	figure legend:st1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10116(rat-hippocampus)|taxid:10116(Rattus norvegicus hippocampal neurons)	-	2020/10/30	2020/10/30	rogid:DtE+ZXAZKdCMvUW5K+jXQ5bH07M10116	rogid:F0BXS2E7Unlk+uNhGFX8SXRN9hA10116	rigid:zzsc1zNhBb5nwIRPeFpYOKgC3M8	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q5XIE8	uniprotkb:P35281	intact:EBI-15348306|ensembl:ENSRNOP00000023037	intact:EBI-917314	psi-mi:itm2b_rat(display_long)|uniprotkb:Itm2b(gene name)|psi-mi:Itm2b(display_short)|uniprotkb:Immature BRI2(gene name synonym)|uniprotkb:Transmembrane protein BRI(gene name synonym)	psi-mi:rab10_rat(display_long)|uniprotkb:Rab10(gene name)|psi-mi:Rab10(display_short)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Martins et al. (2018)	imex:IM-28469|pubmed:29476059	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26440627|imex:IM-28469-5	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSRNOG00000016271(gene)|ensembl:ENSRNOT00000023037(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001540"(amyloid-beta binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0010008"(endosome membrane)|go:"GO:0030660"(Golgi-associated vesicle membrane)|go:"GO:0031301"(integral component of organelle membrane)|go:"GO:0042985"(negative regulation of amyloid precursor protein biosynthetic process)|interpro:IPR007084(BRICHOS)|interpro:IPR040145|mint:Q5XIE8|refseq:NP_001006964.1|rgd:620727	interpro:IPR005225(Small GTP-binding protein)|interpro:IPR001806(Ras GTPase)|rgd:620879|interpro:IPR027417|mint:P35281|go:"GO:0003925"(G protein activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005768"(endosome)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0005886"(plasma membrane)|go:"GO:0005929"(cilium)|go:"GO:0006893"(Golgi to plasma membrane transport)|go:"GO:0006904"(vesicle docking involved in exocytosis)|go:"GO:0007409"(axonogenesis)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0009306"(protein secretion)|go:"GO:0016020"(membrane)|go:"GO:0016192"(vesicle-mediated transport)|go:"GO:0016197"(endosomal transport)|go:"GO:0017157"(regulation of exocytosis)|go:"GO:0019003"(GDP binding)|go:"GO:0019882"(antigen processing and presentation)|go:"GO:0030670"(phagocytic vesicle membrane)|go:"GO:0030859"(polarized epithelial cell differentiation)|go:"GO:0031489"(myosin V binding)|go:"GO:0032593"(insulin-responsive compartment)|go:"GO:0032869"(cellular response to insulin stimulus)|go:"GO:0043001"(Golgi to plasma membrane protein transport)|go:"GO:0045055"(regulated exocytosis)|go:"GO:0045200"(establishment of neuroblast polarity)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051021"(GDP-dissociation inhibitor binding)|go:"GO:0055037"(recycling endosome)|go:"GO:0055038"(recycling endosome membrane)|go:"GO:0070382"(exocytic vesicle)|go:"GO:0071236"(cellular response to antibiotic)|go:"GO:0071782"(endoplasmic reticulum tubular network)|go:"GO:0071786"(endoplasmic reticulum tubular network organization)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0090150"(establishment of protein localization to membrane)|go:"GO:0097051"(establishment of protein localization to endoplasmic reticulum membrane)|go:"GO:0098993"(anchored component of synaptic vesicle membrane)|go:"GO:1903361"(protein localization to basolateral plasma membrane)|reactome:R-RNO-6798695|reactome:R-RNO-8873719|reactome:R-RNO-8876198	-	-	-	figure legend:st1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10116(rat-hippocampus)|taxid:10116(Rattus norvegicus hippocampal neurons)	-	2020/10/30	2020/10/30	rogid:DtE+ZXAZKdCMvUW5K+jXQ5bH07M10116	rogid:QBab92qaS/E5P8CwghgaSofYfu410116	rigid:zzsc1zNhBb5nwIRPeFpYOKgC3M8	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q5XIE8	uniprotkb:P47709	intact:EBI-15348306|ensembl:ENSRNOP00000023037	intact:EBI-1027524	psi-mi:itm2b_rat(display_long)|uniprotkb:Itm2b(gene name)|psi-mi:Itm2b(display_short)|uniprotkb:Immature BRI2(gene name synonym)|uniprotkb:Transmembrane protein BRI(gene name synonym)	psi-mi:rp3a_rat(display_long)|uniprotkb:Rph3a(gene name)|psi-mi:Rph3a(display_short)|uniprotkb:Exophilin-1(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Martins et al. (2018)	imex:IM-28469|pubmed:29476059	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26440627|imex:IM-28469-5	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSRNOG00000016271(gene)|ensembl:ENSRNOT00000023037(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001540"(amyloid-beta binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0010008"(endosome membrane)|go:"GO:0030660"(Golgi-associated vesicle membrane)|go:"GO:0031301"(integral component of organelle membrane)|go:"GO:0042985"(negative regulation of amyloid precursor protein biosynthetic process)|interpro:IPR007084(BRICHOS)|interpro:IPR040145|mint:Q5XIE8|refseq:NP_001006964.1|rgd:620727	go:"GO:0005509"(calcium ion binding)|go:"GO:0005543"(phospholipid binding)|go:"GO:0005544"(calcium-dependent phospholipid binding)|go:"GO:0005546"(phosphatidylinositol-4,5-bisphosphate binding)|go:"GO:0005829"(cytosol)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0007420"(brain development)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0008270"(zinc ion binding)|go:"GO:0008430"(selenium binding)|go:"GO:0019898"(extrinsic component of membrane)|go:"GO:0030141"(secretory granule)|go:"GO:0030672"(synaptic vesicle membrane)|go:"GO:0031267"(small GTPase binding)|go:"GO:0031594"(neuromuscular junction)|go:"GO:0032991"(protein-containing complex)|go:"GO:0042301"(phosphate ion binding)|go:"GO:0043005"(neuron projection)|go:"GO:0043197"(dendritic spine)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045202"(synapse)|go:"GO:0045211"(postsynaptic membrane)|go:"GO:0061669"(spontaneous neurotransmitter secretion)|go:"GO:0070679"(inositol 1,4,5 trisphosphate binding)|go:"GO:0097061"(dendritic spine organization)|go:"GO:0098850"(extrinsic component of synaptic vesicle membrane)|go:"GO:0098981"(cholinergic synapse)|go:"GO:2000310"(regulation of NMDA receptor activity)|rcsb pdb:1ZBD|rcsb pdb:2CHD|rcsb pdb:2CM5|rcsb pdb:2CM6|rcsb pdb:3RPB|rcsb pdb:4LT7|rcsb pdb:4NP9|rcsb pdb:4NS0|rcsb pdb:5LO8|rcsb pdb:5LOB|rcsb pdb:5LOW|rgd:620073|refseq:NP_598202.1|interpro:IPR000008(C2 calcium-dependent membrane targeting)|interpro:IPR010911(Rab-binding)|interpro:IPR001565(Synaptotagmin)|interpro:IPR017455(Zinc finger, FYVE-related)|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR028698|mint:P47709|interpro:IPR035892|interpro:IPR041282|interpro:IPR043566	-	-	-	figure legend:st1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10116(rat-hippocampus)|taxid:10116(Rattus norvegicus hippocampal neurons)	-	2020/10/30	2020/10/30	rogid:DtE+ZXAZKdCMvUW5K+jXQ5bH07M10116	rogid:riq0dOgXETaODPbUSvUER63L6jU10116	rigid:zzsc1zNhBb5nwIRPeFpYOKgC3M8	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q5XIE8	uniprotkb:P11980	intact:EBI-15348306|ensembl:ENSRNOP00000023037	intact:EBI-916419|uniprotkb:P11981|ensembl:ENSRNOP00000015331	psi-mi:itm2b_rat(display_long)|uniprotkb:Itm2b(gene name)|psi-mi:Itm2b(display_short)|uniprotkb:Immature BRI2(gene name synonym)|uniprotkb:Transmembrane protein BRI(gene name synonym)	psi-mi:kpym_rat(display_long)|uniprotkb:Pkm(gene name)|psi-mi:Pkm(display_short)|uniprotkb:Pkm2(gene name synonym)|uniprotkb:Pykm(gene name synonym)|uniprotkb:Pyruvate kinase muscle isozyme(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Martins et al. (2018)	imex:IM-28469|pubmed:29476059	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26440627|imex:IM-28469-5	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSRNOG00000016271(gene)|ensembl:ENSRNOT00000023037(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001540"(amyloid-beta binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0010008"(endosome membrane)|go:"GO:0030660"(Golgi-associated vesicle membrane)|go:"GO:0031301"(integral component of organelle membrane)|go:"GO:0042985"(negative regulation of amyloid precursor protein biosynthetic process)|interpro:IPR007084(BRICHOS)|interpro:IPR040145|mint:Q5XIE8|refseq:NP_001006964.1|rgd:620727	ensembl:ENSRNOG00000011329(gene)|ensembl:ENSRNOT00000015332(transcript)|go:"GO:0000287"(magnesium ion binding)|go:"GO:0001666"(response to hypoxia)|go:"GO:0001889"(liver development)|go:"GO:0003729"(mRNA binding)|go:"GO:0004743"(pyruvate kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005791"(rough endoplasmic reticulum)|go:"GO:0005929"(cilium)|go:"GO:0006006"(glucose metabolic process)|go:"GO:0006096"(glycolytic process)|go:"GO:0006754"(ATP biosynthetic process)|go:"GO:0007584"(response to nutrient)|go:"GO:0009629"(response to gravity)|go:"GO:0010033"(response to organic substance)|go:"GO:0012501"(programmed cell death)|go:"GO:0014870"(response to muscle inactivity)|go:"GO:0016301"(kinase activity)|go:"GO:0030955"(potassium ion binding)|go:"GO:0031100"(animal organ regeneration)|go:"GO:0032868"(response to insulin)|go:"GO:0032869"(cellular response to insulin stimulus)|go:"GO:0042802"(identical protein binding)|go:"GO:0042866"(pyruvate biosynthetic process)|go:"GO:0043403"(skeletal muscle tissue regeneration)|go:"GO:0043531"(ADP binding)|go:"GO:0070324"(thyroid hormone binding)|go:"GO:1902912"(pyruvate kinase complex)|go:"GO:1903672"(positive regulation of sprouting angiogenesis)|go:"GO:2000767"(positive regulation of cytoplasmic translation)|interpro:IPR001697(Pyruvate kinase)|interpro:IPR011037(Pyruvate kinase, beta-barrel-like)|interpro:IPR015793(Pyruvate kinase, barrel)|interpro:IPR015795(Pyruvate kinase, C-terminal-like)|interpro:IPR015806(Pyruvate kinase, beta-barrel)|interpro:IPR015813(Pyruvate/Phosphoenolpyruvate kinase, catalytic core)|interpro:IPR018209|interpro:IPR036918|interpro:IPR040442|mint:P11980|refseq:XP_006243250.2|rgd:3337|refseq:NP_445749.1	-	-	-	figure legend:st1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10116(rat-hippocampus)|taxid:10116(Rattus norvegicus hippocampal neurons)	-	2020/10/30	2020/10/30	rogid:DtE+ZXAZKdCMvUW5K+jXQ5bH07M10116	rogid:GYxco5bbxaUXWMal0+5tWXFouDc10116	rigid:zzsc1zNhBb5nwIRPeFpYOKgC3M8	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q5XIE8	uniprotkb:O35244	intact:EBI-15348306|ensembl:ENSRNOP00000023037	intact:EBI-915490|ensembl:ENSRNOP00000030323	psi-mi:itm2b_rat(display_long)|uniprotkb:Itm2b(gene name)|psi-mi:Itm2b(display_short)|uniprotkb:Immature BRI2(gene name synonym)|uniprotkb:Transmembrane protein BRI(gene name synonym)	psi-mi:prdx6_rat(display_long)|uniprotkb:Antioxidant protein 2(gene name synonym)|uniprotkb:1-Cys peroxiredoxin(gene name synonym)|uniprotkb:Acidic calcium-independent phospholipase A2(gene name synonym)|uniprotkb:Non-selenium glutathione peroxidase(gene name synonym)|uniprotkb:Thiol-specific antioxidant protein(gene name synonym)|uniprotkb:Prdx6(gene name)|psi-mi:Prdx6(display_short)|uniprotkb:Aipla2(gene name synonym)|uniprotkb:Aop2(gene name synonym)|uniprotkb:Tsa(gene name synonym)|uniprotkb:Glutathione-dependent peroxiredoxin(gene name synonym)|uniprotkb:Lysophosphatidylcholine acyltransferase 5(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Martins et al. (2018)	imex:IM-28469|pubmed:29476059	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26440627|imex:IM-28469-5	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSRNOG00000016271(gene)|ensembl:ENSRNOT00000023037(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001540"(amyloid-beta binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0010008"(endosome membrane)|go:"GO:0030660"(Golgi-associated vesicle membrane)|go:"GO:0031301"(integral component of organelle membrane)|go:"GO:0042985"(negative regulation of amyloid precursor protein biosynthetic process)|interpro:IPR007084(BRICHOS)|interpro:IPR040145|mint:Q5XIE8|refseq:NP_001006964.1|rgd:620727	rgd:71005|refseq:NP_446028.1|ensembl:ENSRNOG00000002896(gene)|ensembl:ENSRNOT00000034583(transcript)|go:"GO:0000302"(response to reactive oxygen species)|go:"GO:0004601"(peroxidase activity)|go:"GO:0004602"(glutathione peroxidase activity)|go:"GO:0004623"(phospholipase A2 activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005764"(lysosome)|go:"GO:0005829"(cytosol)|go:"GO:0006979"(response to oxidative stress)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032060"(bleb assembly)|go:"GO:0042744"(hydrogen peroxide catabolic process)|go:"GO:0042802"(identical protein binding)|go:"GO:0045454"(cell redox homeostasis)|go:"GO:0046475"(glycerophospholipid catabolic process)|go:"GO:0047184"(1-acylglycerophosphocholine O-acyltransferase activity)|go:"GO:0047499"(calcium-independent phospholipase A2 activity)|go:"GO:0048026"(positive regulation of mRNA splicing, via spliceosome)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051920"(peroxiredoxin activity)|go:"GO:0098869"(cellular oxidant detoxification)|go:"GO:0102567"|go:"GO:0102568"|interpro:IPR000866(Alkyl hydroperoxide reductase/ Thiol specific antioxidant/ Mal allergen)|interpro:IPR013766(Thioredoxin domain)|interpro:IPR019479|interpro:IPR024706|interpro:IPR036249|mint:O35244|reactome:R-RNO-3299685|reactome:R-RNO-6798695	-	-	-	figure legend:st1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10116(rat-hippocampus)|taxid:10116(Rattus norvegicus hippocampal neurons)	-	2020/10/30	2020/10/30	rogid:DtE+ZXAZKdCMvUW5K+jXQ5bH07M10116	rogid:HbGGY4bUEtG4UTtU/Py7eOaeNJg10116	rigid:zzsc1zNhBb5nwIRPeFpYOKgC3M8	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q5XIE8	uniprotkb:Q63716	intact:EBI-15348306|ensembl:ENSRNOP00000023037	intact:EBI-918674|ensembl:ENSRNOP00000023132	psi-mi:itm2b_rat(display_long)|uniprotkb:Itm2b(gene name)|psi-mi:Itm2b(display_short)|uniprotkb:Immature BRI2(gene name synonym)|uniprotkb:Transmembrane protein BRI(gene name synonym)	psi-mi:prdx1_rat(display_long)|uniprotkb:Thioredoxin peroxidase 2(gene name synonym)|uniprotkb:Thioredoxin-dependent peroxide reductase 2(gene name synonym)|uniprotkb:Heme-binding 23 kDa protein(gene name synonym)|uniprotkb:HBP23(gene name synonym)|uniprotkb:Prdx1(gene name)|psi-mi:Prdx1(display_short)|uniprotkb:Tdpx2(gene name synonym)|uniprotkb:Thioredoxin-dependent peroxiredoxin 1(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Martins et al. (2018)	imex:IM-28469|pubmed:29476059	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26440627|imex:IM-28469-5	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSRNOG00000016271(gene)|ensembl:ENSRNOT00000023037(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001540"(amyloid-beta binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0010008"(endosome membrane)|go:"GO:0030660"(Golgi-associated vesicle membrane)|go:"GO:0031301"(integral component of organelle membrane)|go:"GO:0042985"(negative regulation of amyloid precursor protein biosynthetic process)|interpro:IPR007084(BRICHOS)|interpro:IPR040145|mint:Q5XIE8|refseq:NP_001006964.1|rgd:620727	rgd:620039|refseq:NP_476455.1|ensembl:ENSRNOG00000017194(gene)|ensembl:ENSRNOT00000023132(transcript)|go:"GO:0000302"(response to reactive oxygen species)|go:"GO:0000791"(euchromatin)|go:"GO:0004601"(peroxidase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0005782"(peroxisomal matrix)|go:"GO:0005829"(cytosol)|go:"GO:0006979"(response to oxidative stress)|go:"GO:0008283"(cell population proliferation)|go:"GO:0008379"(thioredoxin peroxidase activity)|go:"GO:0019430"(removal of superoxide radicals)|go:"GO:0020037"(heme binding)|go:"GO:0030101"(natural killer cell activation)|go:"GO:0032872"(regulation of stress-activated MAPK cascade)|go:"GO:0034101"(erythrocyte homeostasis)|go:"GO:0042267"(natural killer cell mediated cytotoxicity)|go:"GO:0042744"(hydrogen peroxide catabolic process)|go:"GO:0042802"(identical protein binding)|go:"GO:0045321"(leukocyte activation)|go:"GO:0045454"(cell redox homeostasis)|go:"GO:0051920"(peroxiredoxin activity)|go:"GO:1901222"(regulation of NIK/NF-kappaB signaling)|interpro:IPR000866(Alkyl hydroperoxide reductase/ Thiol specific antioxidant/ Mal allergen)|interpro:IPR013766(Thioredoxin domain)|interpro:IPR019479|interpro:IPR024706|interpro:IPR036249|mint:Q63716|rcsb pdb:1QQ2|rcsb pdb:2Z9S|reactome:R-RNO-3299685|reactome:R-RNO-5628897	-	-	-	figure legend:st1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10116(rat-hippocampus)|taxid:10116(Rattus norvegicus hippocampal neurons)	-	2020/10/30	2020/10/30	rogid:DtE+ZXAZKdCMvUW5K+jXQ5bH07M10116	rogid:6Yx5rIs6p9cg57ePcRAtiWUM7p010116	rigid:zzsc1zNhBb5nwIRPeFpYOKgC3M8	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q5XIE8	uniprotkb:O08839	intact:EBI-15348306|ensembl:ENSRNOP00000023037	intact:EBI-80095	psi-mi:itm2b_rat(display_long)|uniprotkb:Itm2b(gene name)|psi-mi:Itm2b(display_short)|uniprotkb:Immature BRI2(gene name synonym)|uniprotkb:Transmembrane protein BRI(gene name synonym)	psi-mi:bin1_rat(display_long)|uniprotkb:Bin1(gene name)|psi-mi:Bin1(display_short)|uniprotkb:Amph2(gene name synonym)|uniprotkb:Amphl(gene name synonym)|uniprotkb:Bridging integrator 1(gene name synonym)|uniprotkb:Amphiphysin-like protein(gene name synonym)|uniprotkb:Amphiphysin II(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Martins et al. (2018)	imex:IM-28469|pubmed:29476059	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26440627|imex:IM-28469-5	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSRNOG00000016271(gene)|ensembl:ENSRNOT00000023037(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001540"(amyloid-beta binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0010008"(endosome membrane)|go:"GO:0030660"(Golgi-associated vesicle membrane)|go:"GO:0031301"(integral component of organelle membrane)|go:"GO:0042985"(negative regulation of amyloid precursor protein biosynthetic process)|interpro:IPR007084(BRICHOS)|interpro:IPR040145|mint:Q5XIE8|refseq:NP_001006964.1|rgd:620727	go:"GO:0002020"(protease binding)|go:"GO:0005543"(phospholipid binding)|go:"GO:0005634"(nucleus)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005768"(endosome)|go:"GO:0005874"(microtubule)|go:"GO:0005886"(plasma membrane)|go:"GO:0006997"(nucleus organization)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0008333"(endosome to lysosome transport)|go:"GO:0016020"(membrane)|go:"GO:0019828"(aspartic-type endopeptidase inhibitor activity)|go:"GO:0030018"(Z disc)|go:"GO:0030315"(T-tubule)|go:"GO:0030424"(axon)|go:"GO:0030425"(dendrite)|go:"GO:0030838"(positive regulation of actin filament polymerization)|go:"GO:0031674"(I band)|go:"GO:0031982"(vesicle)|go:"GO:0033268"(node of Ranvier)|go:"GO:0033292"(T-tubule organization)|go:"GO:0042692"(muscle cell differentiation)|go:"GO:0042802"(identical protein binding)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043194"(axon initial segment)|go:"GO:0043196"(varicosity)|go:"GO:0043547"(positive regulation of GTPase activity)|go:"GO:0043679"(axon terminus)|go:"GO:0044300"(cerebellar mossy fiber)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045202"(synapse)|go:"GO:0045664"(regulation of neuron differentiation)|go:"GO:0045807"(positive regulation of endocytosis)|go:"GO:0048156"(tau protein binding)|go:"GO:0048488"(synaptic vesicle endocytosis)|go:"GO:0048711"(positive regulation of astrocyte differentiation)|go:"GO:0051015"(actin filament binding)|go:"GO:0051020"(GTPase binding)|go:"GO:0051087"(chaperone binding)|go:"GO:0051647"(nucleus localization)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0060987"(lipid tube)|go:"GO:0060988"(lipid tube assembly)|go:"GO:0070063"(RNA polymerase binding)|go:"GO:0086091"(regulation of heart rate by cardiac conduction)|go:"GO:0098850"(extrinsic component of synaptic vesicle membrane)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:1901380"(negative regulation of potassium ion transmembrane transport)|go:"GO:1902430"(negative regulation of amyloid-beta formation)|go:"GO:1902960"(negative regulation of aspartic-type endopeptidase activity involved in amyloid precursor protein catabolic process)|go:"GO:1904878"(negative regulation of calcium ion transmembrane transport via high voltage-gated calcium channel)|interpro:IPR001452(Src homology-3)|interpro:IPR003005(Amphiphysin)|interpro:IPR003023(Amphiphysin, isoform 2)|interpro:IPR004148(BAR)|interpro:IPR027267|interpro:IPR035471|interpro:IPR036028|rcsb pdb:1BB9|reactome:R-RNO-8856828|go:"GO:1903946"(negative regulation of ventricular cardiac muscle cell action potential)|rgd:621786|refseq:NP_446411.1|mint:O08839|dip:DIP-30979N	-	-	-	figure legend:st1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10116(rat-hippocampus)|taxid:10116(Rattus norvegicus hippocampal neurons)	-	2020/10/30	2020/10/30	rogid:DtE+ZXAZKdCMvUW5K+jXQ5bH07M10116	rogid:xqcXQWo+FXHjCGGI0Q9agaz9LMk10116	rigid:zzsc1zNhBb5nwIRPeFpYOKgC3M8	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q5XIE8	uniprotkb:F1LP90	intact:EBI-15348306|ensembl:ENSRNOP00000023037	intact:EBI-21999164	psi-mi:itm2b_rat(display_long)|uniprotkb:Itm2b(gene name)|psi-mi:Itm2b(display_short)|uniprotkb:Immature BRI2(gene name synonym)|uniprotkb:Transmembrane protein BRI(gene name synonym)	psi-mi:mink1_rat(display_long)|uniprotkb:GCK family kinase MiNK(gene name synonym)|uniprotkb:MAPK/ERK kinase kinase kinase 6(gene name synonym)|uniprotkb:Misshapen/NIK-related kinase(gene name synonym)|uniprotkb:Mitogen-activated protein kinase kinase kinase kinase 6(gene name synonym)|uniprotkb:Mink1(gene name)|psi-mi:Mink1(display_short)|uniprotkb:Map4k6(gene name synonym)|uniprotkb:Mink(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Martins et al. (2018)	imex:IM-28469|pubmed:29476059	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26440627|imex:IM-28469-5	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSRNOG00000016271(gene)|ensembl:ENSRNOT00000023037(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001540"(amyloid-beta binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0010008"(endosome membrane)|go:"GO:0030660"(Golgi-associated vesicle membrane)|go:"GO:0031301"(integral component of organelle membrane)|go:"GO:0042985"(negative regulation of amyloid precursor protein biosynthetic process)|interpro:IPR007084(BRICHOS)|interpro:IPR040145|mint:Q5XIE8|refseq:NP_001006964.1|rgd:620727	interpro:IPR001180(Citron-like)|interpro:IPR011009(Protein kinase-like)|interpro:IPR000719(Protein kinase, core)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR008271(Serine/threonine protein kinase, active site)|rgd:1359135|mint:F1LP90|go:"GO:0000165"(MAPK cascade)|go:"GO:0001952"(regulation of cell-matrix adhesion)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0007268"(chemical synaptic transmission)|go:"GO:0014069"(postsynaptic density)|go:"GO:0022407"(regulation of cell-cell adhesion)|go:"GO:0030334"(regulation of cell migration)|go:"GO:0030424"(axon)|go:"GO:0030425"(dendrite)|go:"GO:0031532"(actin cytoskeleton reorganization)|go:"GO:0032147"(activation of protein kinase activity)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0043408"(regulation of MAPK cascade)|go:"GO:0045060"(negative thymic T cell selection)|go:"GO:0046330"(positive regulation of JNK cascade)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0048812"(neuron projection morphogenesis)|go:"GO:0048813"(dendrite morphogenesis)|go:"GO:0070050"(neuron cellular homeostasis)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:1900745"(positive regulation of p38MAPK cascade)|go:"GO:2000311"(regulation of AMPA receptor activity)|reactome:R-RNO-2559580	-	-	-	figure legend:st1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10116(rat-hippocampus)|taxid:10116(Rattus norvegicus hippocampal neurons)	-	2020/10/30	2020/10/30	rogid:DtE+ZXAZKdCMvUW5K+jXQ5bH07M10116	rogid:fYUvFtktedoFxUnNJyLwGQu6DLQ10116	rigid:zzsc1zNhBb5nwIRPeFpYOKgC3M8	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q5XIE8	uniprotkb:Q5M7W5	intact:EBI-15348306|ensembl:ENSRNOP00000023037	intact:EBI-26408505|uniprotkb:Q75NR5|uniprotkb:Q75NR6|ensembl:ENSRNOP00000053011	psi-mi:itm2b_rat(display_long)|uniprotkb:Itm2b(gene name)|psi-mi:Itm2b(display_short)|uniprotkb:Immature BRI2(gene name synonym)|uniprotkb:Transmembrane protein BRI(gene name synonym)	psi-mi:map4_rat(display_long)|uniprotkb:Map4(gene name)|psi-mi:Map4(display_short)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Martins et al. (2018)	imex:IM-28469|pubmed:29476059	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26440627|imex:IM-28469-5	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSRNOG00000016271(gene)|ensembl:ENSRNOT00000023037(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001540"(amyloid-beta binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0010008"(endosome membrane)|go:"GO:0030660"(Golgi-associated vesicle membrane)|go:"GO:0031301"(integral component of organelle membrane)|go:"GO:0042985"(negative regulation of amyloid precursor protein biosynthetic process)|interpro:IPR007084(BRICHOS)|interpro:IPR040145|mint:Q5XIE8|refseq:NP_001006964.1|rgd:620727	refseq:NP_001019449.1|rgd:1564359|ensembl:ENSRNOG00000020748(gene)|ensembl:ENSRNOT00000056166(transcript)|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0005874"(microtubule)|go:"GO:0005930"(axoneme)|go:"GO:0007052"(mitotic spindle organization)|go:"GO:0008017"(microtubule binding)|go:"GO:0030424"(axon)|go:"GO:0014069"(postsynaptic density)|go:"GO:0031175"(neuron projection development)|go:"GO:0043005"(neuron projection)|go:"GO:0051012"(microtubule sliding)|go:"GO:0051294"(establishment of spindle orientation)|go:"GO:0051301"(cell division)|go:"GO:0072686"(mitotic spindle)|go:"GO:1902856"(negative regulation of non-motile cilium assembly)|interpro:IPR001084(Tubulin-binding Tau protein)|interpro:IPR027323|mint:Q5M7W5	-	-	-	figure legend:st1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10116(rat-hippocampus)|taxid:10116(Rattus norvegicus hippocampal neurons)	-	2020/10/30	2020/10/30	rogid:DtE+ZXAZKdCMvUW5K+jXQ5bH07M10116	rogid:wJ/zwFbSbQkk3JEQjUQjVIHMtmk10116	rigid:zzsc1zNhBb5nwIRPeFpYOKgC3M8	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q5XIE8	uniprotkb:P34926	intact:EBI-15348306|ensembl:ENSRNOP00000023037	intact:EBI-631571	psi-mi:itm2b_rat(display_long)|uniprotkb:Itm2b(gene name)|psi-mi:Itm2b(display_short)|uniprotkb:Immature BRI2(gene name synonym)|uniprotkb:Transmembrane protein BRI(gene name synonym)	psi-mi:map1a_rat(display_long)|uniprotkb:Map1a(gene name)|psi-mi:Map1a(display_short)|uniprotkb:Mtap1a(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Martins et al. (2018)	imex:IM-28469|pubmed:29476059	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26440627|imex:IM-28469-5	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSRNOG00000016271(gene)|ensembl:ENSRNOT00000023037(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001540"(amyloid-beta binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0010008"(endosome membrane)|go:"GO:0030660"(Golgi-associated vesicle membrane)|go:"GO:0031301"(integral component of organelle membrane)|go:"GO:0042985"(negative regulation of amyloid precursor protein biosynthetic process)|interpro:IPR007084(BRICHOS)|interpro:IPR040145|mint:Q5XIE8|refseq:NP_001006964.1|rgd:620727	rgd:3042|refseq:NP_112257.1|go:"GO:0007026"(negative regulation of microtubule depolymerization)|go:"GO:0007409"(axonogenesis)|go:"GO:0007605"(sensory perception of sound)|go:"GO:0007613"(memory)|go:"GO:0008017"(microtubule binding)|go:"GO:0008093"(cytoskeletal anchor activity)|go:"GO:0008306"(associative learning)|go:"GO:0014069"(postsynaptic density)|go:"GO:0015631"(tubulin binding)|go:"GO:0016358"(dendrite development)|go:"GO:0030424"(axon)|go:"GO:0030425"(dendrite)|go:"GO:0031114"(regulation of microtubule depolymerization)|go:"GO:0032435"(negative regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0035255"(ionotropic glutamate receptor binding)|go:"GO:0043005"(neuron projection)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043194"(axon initial segment)|go:"GO:0043198"(dendritic shaft)|go:"GO:0044307"(dendritic branch)|go:"GO:0045202"(synapse)|go:"GO:0045494"(photoreceptor cell maintenance)|go:"GO:0048167"(regulation of synaptic plasticity)|go:"GO:0050882"(voluntary musculoskeletal movement)|go:"GO:0070050"(neuron cellular homeostasis)|go:"GO:0099641"(anterograde axonal protein transport)|go:"GO:0099642"(retrograde axonal protein transport)|go:"GO:0150001"(primary dendrite)|go:"GO:1901588"(dendritic microtubule)|go:"GO:1902817"(negative regulation of protein localization to microtubule)|go:"GO:1903829"(positive regulation of protein localization)|go:"GO:1904115"(axon cytoplasm)|go:"GO:1990535"(neuron projection maintenance)|go:"GO:2000010"(positive regulation of protein localization to cell surface)|interpro:IPR015656(MAP1A)|interpro:IPR026074|interpro:IPR036866|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0001750"(photoreceptor outer segment)|go:"GO:0003779"(actin binding)|go:"GO:0005518"(collagen binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005874"(microtubule)|go:"GO:0005875"(microtubule associated complex)|mint:P34926|dip:DIP-29265N	-	-	-	figure legend:st1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10116(rat-hippocampus)|taxid:10116(Rattus norvegicus hippocampal neurons)	-	2020/10/30	2020/10/30	rogid:DtE+ZXAZKdCMvUW5K+jXQ5bH07M10116	rogid:KoMmjz9oNsuegJgHeF2bcf+Ybhs10116	rigid:zzsc1zNhBb5nwIRPeFpYOKgC3M8	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q5XIE8	uniprotkb:P43244	intact:EBI-15348306|ensembl:ENSRNOP00000023037	intact:EBI-16220483|uniprotkb:O35833|uniprotkb:Q5DVW1	psi-mi:itm2b_rat(display_long)|uniprotkb:Itm2b(gene name)|psi-mi:Itm2b(display_short)|uniprotkb:Immature BRI2(gene name synonym)|uniprotkb:Transmembrane protein BRI(gene name synonym)	psi-mi:matr3_rat(display_long)|uniprotkb:Matr3(gene name)|psi-mi:Matr3(display_short)|uniprotkb:Nuclear scaffold protein p130/MAT3(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Martins et al. (2018)	imex:IM-28469|pubmed:29476059	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26440627|imex:IM-28469-5	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSRNOG00000016271(gene)|ensembl:ENSRNOT00000023037(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001540"(amyloid-beta binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0010008"(endosome membrane)|go:"GO:0030660"(Golgi-associated vesicle membrane)|go:"GO:0031301"(integral component of organelle membrane)|go:"GO:0042985"(negative regulation of amyloid precursor protein biosynthetic process)|interpro:IPR007084(BRICHOS)|interpro:IPR040145|mint:Q5XIE8|refseq:NP_001006964.1|rgd:620727	go:"GO:0001825"(blastocyst formation)|go:"GO:0002218"(activation of innate immune response)|go:"GO:0003170"(heart valve development)|go:"GO:0003281"(ventricular septum development)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0008270"(zinc ion binding)|go:"GO:0010608"(posttranscriptional regulation of gene expression)|go:"GO:0016363"(nuclear matrix)|go:"GO:0035198"(miRNA binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0045087"(innate immune response)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|mint:P43244|rgd:3052|refseq:NP_062022.2|refseq:XP_006254596.1|refseq:XP_017456375.1|refseq:XP_017456376.1|interpro:IPR034928|interpro:IPR034930|interpro:IPR000690(Zinc finger, C2H2-type matrin)|interpro:IPR003604(Zinc finger, U1-type)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR035979	-	-	-	figure legend:st1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10116(rat-hippocampus)|taxid:10116(Rattus norvegicus hippocampal neurons)	-	2020/10/30	2020/10/30	rogid:DtE+ZXAZKdCMvUW5K+jXQ5bH07M10116	rogid:cIeIMjPK3/Ejwo7M0bBIRomzo+810116	rigid:zzsc1zNhBb5nwIRPeFpYOKgC3M8	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q5XIE8	uniprotkb:P97829	intact:EBI-15348306|ensembl:ENSRNOP00000023037	intact:EBI-15185922|ensembl:ENSRNOP00000050938|ensembl:ENSRNOP00000071430|uniprotkb:O35294	psi-mi:itm2b_rat(display_long)|uniprotkb:Itm2b(gene name)|psi-mi:Itm2b(display_short)|uniprotkb:Immature BRI2(gene name synonym)|uniprotkb:Transmembrane protein BRI(gene name synonym)	psi-mi:cd47_rat(display_long)|uniprotkb:Integrin-associated protein(gene name synonym)|uniprotkb:Cd47(gene name)|psi-mi:Cd47(display_short)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Martins et al. (2018)	imex:IM-28469|pubmed:29476059	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26440627|imex:IM-28469-5	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSRNOG00000016271(gene)|ensembl:ENSRNOT00000023037(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001540"(amyloid-beta binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0010008"(endosome membrane)|go:"GO:0030660"(Golgi-associated vesicle membrane)|go:"GO:0031301"(integral component of organelle membrane)|go:"GO:0042985"(negative regulation of amyloid precursor protein biosynthetic process)|interpro:IPR007084(BRICHOS)|interpro:IPR040145|mint:Q5XIE8|refseq:NP_001006964.1|rgd:620727	ensembl:ENSRNOG00000001964(gene)|ensembl:ENSRNOT00000050142(transcript)|ensembl:ENSRNOT00000078434(transcript)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006954"(inflammatory response)|go:"GO:0007229"(integrin-mediated signaling pathway)|go:"GO:0008228"(opsonization)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0009617"(response to bacterium)|go:"GO:0009986"(cell surface)|go:"GO:0016477"(cell migration)|go:"GO:0022409"(positive regulation of cell-cell adhesion)|go:"GO:0032649"(regulation of interferon-gamma production)|go:"GO:0032655"(regulation of interleukin-12 production)|go:"GO:0032675"(regulation of interleukin-6 production)|go:"GO:0032680"(regulation of tumor necrosis factor production)|go:"GO:0045428"(regulation of nitric oxide biosynthetic process)|go:"GO:0050729"(positive regulation of inflammatory response)|go:"GO:0050766"(positive regulation of phagocytosis)|go:"GO:0050870"(positive regulation of T cell activation)|go:"GO:0051496"(positive regulation of stress fiber assembly)|go:"GO:0070053"(thrombospondin receptor activity)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070487"(monocyte aggregation)|go:"GO:0071346"(cellular response to interferon-gamma)|go:"GO:0071347"(cellular response to interleukin-1)|go:"GO:0071349"(cellular response to interleukin-12)|go:"GO:0086080"(protein binding involved in heterotypic cell-cell adhesion)|go:"GO:0098632"(cell-cell adhesion mediator activity)|go:"GO:1904669"(ATP export)|go:"GO:1905450"(negative regulation of Fc-gamma receptor signaling pathway involved in phagocytosis)|go:"GO:2000439"(positive regulation of monocyte extravasation)|interpro:IPR006704(CD47 integrin associated protein)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR013147(CD47 transmembrane)|interpro:IPR013270(CD47 immunoglobulin-like)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR037805|mint:P97829|reactome:R-RNO-202733|reactome:R-RNO-216083|reactome:R-RNO-391160|reactome:R-RNO-6798695|go:"GO:0032653"(regulation of interleukin-10 production)|refseq:NP_062068.1|rgd:2308	-	-	-	figure legend:st1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10116(rat-hippocampus)|taxid:10116(Rattus norvegicus hippocampal neurons)	-	2020/10/30	2020/10/30	rogid:DtE+ZXAZKdCMvUW5K+jXQ5bH07M10116	rogid:NDbHpeXvgK2ywSf2y9vmcTC0flU10116	rigid:zzsc1zNhBb5nwIRPeFpYOKgC3M8	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q5XIE8	uniprotkb:Q9WVE9	intact:EBI-15348306|ensembl:ENSRNOP00000023037	intact:EBI-6095170|uniprotkb:Q9WVE1|uniprotkb:F1M823|uniprotkb:D3ZV52|ensembl:ENSRNOP00000044773	psi-mi:itm2b_rat(display_long)|uniprotkb:Itm2b(gene name)|psi-mi:Itm2b(display_short)|uniprotkb:Immature BRI2(gene name synonym)|uniprotkb:Transmembrane protein BRI(gene name synonym)	psi-mi:itsn1_rat(display_long)|uniprotkb:Itsn1(gene name)|psi-mi:Itsn1(display_short)|uniprotkb:Ehsh1(gene name synonym)|uniprotkb:Itsn(gene name synonym)|uniprotkb:EH domain and SH3 domain regulator of endocytosis 1(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Martins et al. (2018)	imex:IM-28469|pubmed:29476059	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26440627|imex:IM-28469-5	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSRNOG00000016271(gene)|ensembl:ENSRNOT00000023037(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001540"(amyloid-beta binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0010008"(endosome membrane)|go:"GO:0030660"(Golgi-associated vesicle membrane)|go:"GO:0031301"(integral component of organelle membrane)|go:"GO:0042985"(negative regulation of amyloid precursor protein biosynthetic process)|interpro:IPR007084(BRICHOS)|interpro:IPR040145|mint:Q5XIE8|refseq:NP_001006964.1|rgd:620727	rgd:2935|refseq:NP_062100.1|refseq:NP_001129568.1|ensembl:ENSRNOG00000002001(gene)|ensembl:ENSRNOT00000042750(transcript)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0005905"(clathrin-coated pit)|go:"GO:0006887"(exocytosis)|go:"GO:0006897"(endocytosis)|go:"GO:0007264"(small GTPase mediated signal transduction)|go:"GO:0007420"(brain development)|go:"GO:0015031"(protein transport)|go:"GO:0016197"(endosomal transport)|go:"GO:0019209"(kinase activator activity)|go:"GO:0030027"(lamellipodium)|go:"GO:0030139"(endocytic vesicle)|go:"GO:0034613"(cellular protein localization)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043195"(terminal bouton)|go:"GO:0043197"(dendritic spine)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0044305"(calyx of Held)|go:"GO:0045202"(synapse)|go:"GO:0048488"(synaptic vesicle endocytosis)|go:"GO:0051897"(positive regulation of protein kinase B signaling)|go:"GO:0055037"(recycling endosome)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0060124"(positive regulation of growth hormone secretion)|go:"GO:0060999"(positive regulation of dendritic spine development)|go:"GO:0070064"(proline-rich region binding)|go:"GO:0097440"(apical dendrite)|go:"GO:0097708"(intracellular vesicle)|go:"GO:0098833"(presynaptic endocytic zone)|go:"GO:0098871"(postsynaptic actin cytoskeleton)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0150007"(clathrin-dependent synaptic vesicle endocytosis)|go:"GO:1905274"(regulation of modification of postsynaptic actin cytoskeleton)|go:"GO:2001288"(positive regulation of caveolin-mediated endocytosis)|interpro:IPR000008(C2 calcium-dependent membrane targeting)|interpro:IPR000219("Dbl homology (DH) domain")|interpro:IPR000261("EPS15 homology (EH)")|interpro:IPR001331(Guanine-nucleotide dissociation stimulator, CDC24, conserved site)|interpro:IPR001452(Src homology-3)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR002048(Calcium-binding EF-hand)|interpro:IPR011992(EF-Hand type)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR018247|interpro:IPR035892|interpro:IPR035899|interpro:IPR036028|mint:Q9WVE9|rcsb pdb:3HS9|reactome:R-RNO-193648|reactome:R-RNO-3928662|reactome:R-RNO-416482|reactome:R-RNO-8856825|reactome:R-RNO-8856828|reactome:R-RNO-9013148|reactome:R-RNO-9013406|reactome:R-RNO-9013408	-	-	-	figure legend:st1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10116(rat-hippocampus)|taxid:10116(Rattus norvegicus hippocampal neurons)	-	2020/10/30	2020/10/30	rogid:DtE+ZXAZKdCMvUW5K+jXQ5bH07M10116	rogid:JoCpbC+c8T4fn7jqgQEtPXiYaW810116	rigid:zzsc1zNhBb5nwIRPeFpYOKgC3M8	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q5XIE8	uniprotkb:Q63416	intact:EBI-15348306|ensembl:ENSRNOP00000023037	intact:EBI-15348287|ensembl:ENSRNOP00000023984	psi-mi:itm2b_rat(display_long)|uniprotkb:Itm2b(gene name)|psi-mi:Itm2b(display_short)|uniprotkb:Immature BRI2(gene name synonym)|uniprotkb:Transmembrane protein BRI(gene name synonym)	psi-mi:itih3_rat(display_long)|uniprotkb:Itih3(gene name)|psi-mi:Itih3(display_short)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Martins et al. (2018)	imex:IM-28469|pubmed:29476059	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26440627|imex:IM-28469-5	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSRNOG00000016271(gene)|ensembl:ENSRNOT00000023037(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001540"(amyloid-beta binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0010008"(endosome membrane)|go:"GO:0030660"(Golgi-associated vesicle membrane)|go:"GO:0031301"(integral component of organelle membrane)|go:"GO:0042985"(negative regulation of amyloid precursor protein biosynthetic process)|interpro:IPR007084(BRICHOS)|interpro:IPR040145|mint:Q5XIE8|refseq:NP_001006964.1|rgd:620727	interpro:IPR002035(von Willebrand factor, type A)|interpro:IPR010600(Inter-alpha-trypsin inhibitor heavy chain, C-terminal)|ensembl:ENSRNOG00000017689(gene)|ensembl:ENSRNOT00000023984(transcript)|go:"GO:0004867"(serine-type endopeptidase inhibitor activity)|go:"GO:0005576"(extracellular region)|go:"GO:0030212"(hyaluronan metabolic process)|interpro:IPR036465|mint:Q63416|reactome:R-RNO-114608|interpro:IPR013694(Vault protein inter-alpha-trypsin)|refseq:NP_059047.1|rgd:620633	-	-	-	figure legend:st1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10116(rat-hippocampus)|taxid:10116(Rattus norvegicus hippocampal neurons)	-	2020/10/30	2020/10/30	rogid:DtE+ZXAZKdCMvUW5K+jXQ5bH07M10116	rogid:FYOFGuKPLOm1smHocQOD0RN7Qy810116	rigid:zzsc1zNhBb5nwIRPeFpYOKgC3M8	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q5XIE8	uniprotkb:D3ZGS3	intact:EBI-15348306|ensembl:ENSRNOP00000023037	intact:EBI-26439631|ensembl:ENSRNOP00000072408	psi-mi:itm2b_rat(display_long)|uniprotkb:Itm2b(gene name)|psi-mi:Itm2b(display_short)|uniprotkb:Immature BRI2(gene name synonym)|uniprotkb:Transmembrane protein BRI(gene name synonym)	psi-mi:ocrl_rat(display_long)|uniprotkb:Ocrl(gene name)|psi-mi:Ocrl(display_short)|uniprotkb:Inositol polyphosphate 5-phosphatase OCRL-1(gene name synonym)|uniprotkb:Phosphatidylinositol 3,4,5-triphosphate 5-phosphatase(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Martins et al. (2018)	imex:IM-28469|pubmed:29476059	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26440627|imex:IM-28469-5	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSRNOG00000016271(gene)|ensembl:ENSRNOT00000023037(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001540"(amyloid-beta binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0010008"(endosome membrane)|go:"GO:0030660"(Golgi-associated vesicle membrane)|go:"GO:0031301"(integral component of organelle membrane)|go:"GO:0042985"(negative regulation of amyloid precursor protein biosynthetic process)|interpro:IPR007084(BRICHOS)|interpro:IPR040145|mint:Q5XIE8|refseq:NP_001006964.1|rgd:620727	reactome:R-RNO-9013423|reactome:R-RNO-9013409|ensembl:ENSRNOG00000003875(gene)|ensembl:ENSRNOT00000082363(transcript)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0001750"(photoreceptor outer segment)|go:"GO:0004439"(phosphatidylinositol-4,5-bisphosphate 5-phosphatase activity)|go:"GO:0004445"(inositol-polyphosphate 5-phosphatase activity)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005769"(early endosome)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0005886"(plasma membrane)|go:"GO:0005905"(clathrin-coated pit)|go:"GO:0007165"(signal transduction)|go:"GO:0016020"(membrane)|go:"GO:0030136"(clathrin-coated vesicle)|go:"GO:0030670"(phagocytic vesicle membrane)|go:"GO:0031267"(small GTPase binding)|go:"GO:0031901"(early endosome membrane)|go:"GO:0034485"(phosphatidylinositol-3,4,5-trisphosphate 5-phosphatase activity)|go:"GO:0043087"(regulation of GTPase activity)|go:"GO:0046855"(inositol phosphate dephosphorylation)|go:"GO:0046856"(phosphatidylinositol dephosphorylation)|go:"GO:0052658"(inositol-1,4,5-trisphosphate 5-phosphatase activity)|go:"GO:0052659"(inositol-1,3,4,5-tetrakisphosphate 5-phosphatase activity)|go:"GO:0052745"(inositol phosphate phosphatase activity)|go:"GO:0060271"(cilium assembly)|interpro:IPR000198(RhoGAP)|interpro:IPR000300(Inositol polyphosphate related phosphatase)|interpro:IPR005135(Endonuclease/exonuclease/phosphatase)|interpro:IPR008936(Rho GTPase activation protein)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR031995|interpro:IPR036691|interpro:IPR037787|interpro:IPR037793|mint:D3ZGS3|reactome:R-RNO-1660499|reactome:R-RNO-1660514|reactome:R-RNO-1855183|reactome:R-RNO-1855204|reactome:R-RNO-432722|reactome:R-RNO-8856828|rgd:1594526	-	-	-	figure legend:st1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10116(rat-hippocampus)|taxid:10116(Rattus norvegicus hippocampal neurons)	-	2020/10/30	2020/10/30	rogid:DtE+ZXAZKdCMvUW5K+jXQ5bH07M10116	rogid:Gg8sTYtHO1a00q+kPNFzx1/8Os410116	rigid:zzsc1zNhBb5nwIRPeFpYOKgC3M8	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q5XIE8	uniprotkb:P20761	intact:EBI-15348306|ensembl:ENSRNOP00000023037	intact:EBI-5747204|ensembl:ENSRNOP00000044037	psi-mi:itm2b_rat(display_long)|uniprotkb:Itm2b(gene name)|psi-mi:Itm2b(display_short)|uniprotkb:Immature BRI2(gene name synonym)|uniprotkb:Transmembrane protein BRI(gene name synonym)	psi-mi:igg2b_rat(display_long)|uniprotkb:Igh-1a(gene name)|psi-mi:Igh-1a(display_short)|uniprotkb:Immunoglobulin heavy chain 1a(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Martins et al. (2018)	imex:IM-28469|pubmed:29476059	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26440627|imex:IM-28469-5	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSRNOG00000016271(gene)|ensembl:ENSRNOT00000023037(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001540"(amyloid-beta binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0010008"(endosome membrane)|go:"GO:0030660"(Golgi-associated vesicle membrane)|go:"GO:0031301"(integral component of organelle membrane)|go:"GO:0042985"(negative regulation of amyloid precursor protein biosynthetic process)|interpro:IPR007084(BRICHOS)|interpro:IPR040145|mint:Q5XIE8|refseq:NP_001006964.1|rgd:620727	rgd:1305720|ensembl:ENSRNOG00000048402(gene)|ensembl:ENSRNOT00000045874(transcript)|go:"GO:0003823"(antigen binding)|go:"GO:0006910"(phagocytosis, recognition)|go:"GO:0006911"(phagocytosis, engulfment)|go:"GO:0006958"(complement activation, classical pathway)|go:"GO:0009897"(external side of plasma membrane)|go:"GO:0034987"(immunoglobulin receptor binding)|go:"GO:0042571"(immunoglobulin complex, circulating)|go:"GO:0042742"(defense response to bacterium)|go:"GO:0045087"(innate immune response)|go:"GO:0050853"(B cell receptor signaling pathway)|go:"GO:0050871"(positive regulation of B cell activation)|interpro:IPR003006(Immunoglobulin/major histocompatibility complex, conserved site)|interpro:IPR003597(Immunoglobulin C1-set)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR036179|mint:P20761|rcsb pdb:1C5D|rcsb pdb:2ARJ|rcsb pdb:3B9K|rcsb pdb:1BFO	-	-	-	figure legend:st1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10116(rat-hippocampus)|taxid:10116(Rattus norvegicus hippocampal neurons)	-	2020/10/30	2020/10/30	rogid:DtE+ZXAZKdCMvUW5K+jXQ5bH07M10116	rogid:YP3+ZkBaG+Trma6Rnzpb8qwV8xg10116	rigid:zzsc1zNhBb5nwIRPeFpYOKgC3M8	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q5XIE8	uniprotkb:P0C0S7	intact:EBI-15348306|ensembl:ENSRNOP00000023037	intact:EBI-26439581|uniprotkb:P17317|uniprotkb:Q5U5H6	psi-mi:itm2b_rat(display_long)|uniprotkb:Itm2b(gene name)|psi-mi:Itm2b(display_short)|uniprotkb:Immature BRI2(gene name synonym)|uniprotkb:Transmembrane protein BRI(gene name synonym)	psi-mi:h2az_rat(display_long)|uniprotkb:H2az1(gene name)|psi-mi:H2az1(display_short)|uniprotkb:H2afz(gene name synonym)|uniprotkb:H2az(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Martins et al. (2018)	imex:IM-28469|pubmed:29476059	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26440627|imex:IM-28469-5	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSRNOG00000016271(gene)|ensembl:ENSRNOT00000023037(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001540"(amyloid-beta binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0010008"(endosome membrane)|go:"GO:0030660"(Golgi-associated vesicle membrane)|go:"GO:0031301"(integral component of organelle membrane)|go:"GO:0042985"(negative regulation of amyloid precursor protein biosynthetic process)|interpro:IPR007084(BRICHOS)|interpro:IPR040145|mint:Q5XIE8|refseq:NP_001006964.1|rgd:620727	reactome:R-RNO-201722|reactome:R-RNO-212300|reactome:R-RNO-2299718|reactome:R-RNO-2559580|reactome:R-RNO-2559582|reactome:R-RNO-2559586|reactome:R-RNO-427359|reactome:R-RNO-427413|reactome:R-RNO-5250924|reactome:R-RNO-5578749|reactome:R-RNO-5625886|reactome:R-RNO-606279|reactome:R-RNO-73728|reactome:R-RNO-73772|reactome:R-RNO-8936459|reactome:R-RNO-9018519|reactome:R-RNO-9670095|reactome:R-RNO-171306|go:"GO:0000786"(nucleosome)|go:"GO:0000791"(euchromatin)|go:"GO:0000792"(heterochromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000979"(RNA polymerase II core promoter sequence-specific DNA binding)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0006342"|go:"GO:0031490"(chromatin DNA binding)|go:"GO:0031492"(nucleosomal DNA binding)|go:"GO:0032869"(cellular response to insulin stimulus)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0071392"(cellular response to estradiol stimulus)|reactome:R-RNO-110330|reactome:R-RNO-110331|mint:P0C0S7|refseq:NP_073165.1|interpro:IPR009072(Histone-fold)|interpro:IPR002119(Histone H2A)|interpro:IPR007125(Histone core)|interpro:IPR032454|interpro:IPR032458|rgd:621464	-	-	-	figure legend:st1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10116(rat-hippocampus)|taxid:10116(Rattus norvegicus hippocampal neurons)	-	2020/10/30	2020/10/30	rogid:DtE+ZXAZKdCMvUW5K+jXQ5bH07M10116	rogid:0FrzM1TXlduSQ0NNVl0C9uqCUGI10116	rigid:zzsc1zNhBb5nwIRPeFpYOKgC3M8	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q5XIE8	uniprotkb:P05708	intact:EBI-15348306|ensembl:ENSRNOP00000023037	intact:EBI-2255913	psi-mi:itm2b_rat(display_long)|uniprotkb:Itm2b(gene name)|psi-mi:Itm2b(display_short)|uniprotkb:Immature BRI2(gene name synonym)|uniprotkb:Transmembrane protein BRI(gene name synonym)	psi-mi:hxk1_rat(display_long)|uniprotkb:Hk1(gene name)|psi-mi:Hk1(display_short)|uniprotkb:Hexokinase type I(gene name synonym)|uniprotkb:Brain form hexokinase(gene name synonym)|uniprotkb:Hexokinase-A(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Martins et al. (2018)	imex:IM-28469|pubmed:29476059	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26440627|imex:IM-28469-5	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSRNOG00000016271(gene)|ensembl:ENSRNOT00000023037(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001540"(amyloid-beta binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0010008"(endosome membrane)|go:"GO:0030660"(Golgi-associated vesicle membrane)|go:"GO:0031301"(integral component of organelle membrane)|go:"GO:0042985"(negative regulation of amyloid precursor protein biosynthetic process)|interpro:IPR007084(BRICHOS)|interpro:IPR040145|mint:Q5XIE8|refseq:NP_001006964.1|rgd:620727	rgd:2796|refseq:NP_036866.1|interpro:IPR001312(Hexokinase)|interpro:IPR022673|interpro:IPR019807|interpro:IPR022672|interpro:IPR043129|mint:P05708|go:"GO:0001666"(response to hypoxia)|go:"GO:0001678"(cellular glucose homeostasis)|go:"GO:0002720"(positive regulation of cytokine production involved in immune response)|go:"GO:0002931"(response to ischemia)|go:"GO:0004340"(glucokinase activity)|go:"GO:0004396"(hexokinase activity)|go:"GO:0004672"(protein kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005536"(glucose binding)|go:"GO:0005739"(mitochondrion)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005829"(cytosol)|go:"GO:0005901"(caveola)|go:"GO:0006002"(fructose 6-phosphate metabolic process)|go:"GO:0006013"(mannose metabolic process)|go:"GO:0006096"(glycolytic process)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0006954"(inflammatory response)|go:"GO:0008865"(fructokinase activity)|go:"GO:0009741"(response to brassinosteroid)|go:"GO:0010359"(regulation of anion channel activity)|go:"GO:0018105"(peptidyl-serine phosphorylation)|go:"GO:0018107"(peptidyl-threonine phosphorylation)|go:"GO:0018108"(peptidyl-tyrosine phosphorylation)|go:"GO:0019158"(mannokinase activity)|go:"GO:0032731"(positive regulation of interleukin-1 beta production)|go:"GO:0032991"(protein-containing complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0042834"(peptidoglycan binding)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045087"(innate immune response)|go:"GO:0045121"(membrane raft)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0046835"(carbohydrate phosphorylation)|go:"GO:0047931"(glucosamine kinase activity)|go:"GO:0051156"(glucose 6-phosphate metabolic process)|go:"GO:0072655"(establishment of protein localization to mitochondrion)|go:"GO:0072656"(maintenance of protein location in mitochondrion)|go:"GO:1901986"(response to ketamine)|rcsb pdb:1BG3|reactome:R-RNO-70171	-	-	-	figure legend:st1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10116(rat-hippocampus)|taxid:10116(Rattus norvegicus hippocampal neurons)	-	2020/10/30	2020/10/30	rogid:DtE+ZXAZKdCMvUW5K+jXQ5bH07M10116	rogid:Qr89EiLOcvIkO2EN+U+iWjMybSc10116	rigid:zzsc1zNhBb5nwIRPeFpYOKgC3M8	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q5XIE8	uniprotkb:P53534	intact:EBI-15348306|ensembl:ENSRNOP00000023037	intact:EBI-2696349	psi-mi:itm2b_rat(display_long)|uniprotkb:Itm2b(gene name)|psi-mi:Itm2b(display_short)|uniprotkb:Immature BRI2(gene name synonym)|uniprotkb:Transmembrane protein BRI(gene name synonym)	psi-mi:pygb_rat(display_long)|uniprotkb:Pygb(gene name)|psi-mi:Pygb(display_short)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Martins et al. (2018)	imex:IM-28469|pubmed:29476059	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26440627|imex:IM-28469-5	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSRNOG00000016271(gene)|ensembl:ENSRNOT00000023037(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001540"(amyloid-beta binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0010008"(endosome membrane)|go:"GO:0030660"(Golgi-associated vesicle membrane)|go:"GO:0031301"(integral component of organelle membrane)|go:"GO:0042985"(negative regulation of amyloid precursor protein biosynthetic process)|interpro:IPR007084(BRICHOS)|interpro:IPR040145|mint:Q5XIE8|refseq:NP_001006964.1|rgd:620727	interpro:IPR035090|rgd:3460|refseq:NP_037320.1|interpro:IPR011833(Glycogen/starch/alpha-glucan phosphorylase)|interpro:IPR000811(Glycosyl transferase, family 35)|mint:P53534|go:"GO:0005737"(cytoplasm)|go:"GO:0005977"(glycogen metabolic process)|go:"GO:0005980"(glycogen catabolic process)|go:"GO:0008184"(glycogen phosphorylase activity)|go:"GO:0030170"(pyridoxal phosphate binding)|go:"GO:0030246"(carbohydrate binding)|go:"GO:0030424"(axon)|go:"GO:0042802"(identical protein binding)|go:"GO:0102250"(linear malto-oligosaccharide phosphorylase activity)|go:"GO:0102499"(SHG alpha-glucan phosphorylase activity)|reactome:R-RNO-6798695	-	-	-	figure legend:st1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10116(rat-hippocampus)|taxid:10116(Rattus norvegicus hippocampal neurons)	-	2020/10/30	2020/10/30	rogid:DtE+ZXAZKdCMvUW5K+jXQ5bH07M10116	rogid:WcV4oiXMS78KKpVSzVnziBt5uD810116	rigid:zzsc1zNhBb5nwIRPeFpYOKgC3M8	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q5XIE8	uniprotkb:P05065	intact:EBI-15348306|ensembl:ENSRNOP00000023037	intact:EBI-522118|uniprotkb:Q63038|ensembl:ENSRNOP00000068764|ensembl:ENSRNOP00000069507|ensembl:ENSRNOP00000069540	psi-mi:itm2b_rat(display_long)|uniprotkb:Itm2b(gene name)|psi-mi:Itm2b(display_short)|uniprotkb:Immature BRI2(gene name synonym)|uniprotkb:Transmembrane protein BRI(gene name synonym)	psi-mi:aldoa_rat(display_long)|uniprotkb:Muscle-type aldolase(gene name synonym)|uniprotkb:Aldoa(gene name)|psi-mi:Aldoa(display_short)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Martins et al. (2018)	imex:IM-28469|pubmed:29476059	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26440627|imex:IM-28469-5	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSRNOG00000016271(gene)|ensembl:ENSRNOT00000023037(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001540"(amyloid-beta binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0010008"(endosome membrane)|go:"GO:0030660"(Golgi-associated vesicle membrane)|go:"GO:0031301"(integral component of organelle membrane)|go:"GO:0042985"(negative regulation of amyloid precursor protein biosynthetic process)|interpro:IPR007084(BRICHOS)|interpro:IPR040145|mint:Q5XIE8|refseq:NP_001006964.1|rgd:620727	rgd:2089|refseq:NP_001170776.1|refseq:NP_036627.1|ensembl:ENSRNOG00000052802(gene)|ensembl:ENSRNOT00000080988(transcript)|ensembl:ENSRNOT00000087928(transcript)|ensembl:ENSRNOT00000088473(transcript)|go:"GO:0000792"(heterochromatin)|go:"GO:0001666"(response to hypoxia)|go:"GO:0002020"(protease binding)|go:"GO:0004332"(fructose-bisphosphate aldolase activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006096"(glycolytic process)|go:"GO:0009408"(response to heat)|go:"GO:0016020"(membrane)|go:"GO:0019242"(methylglyoxal biosynthetic process)|go:"GO:0030018"(Z disc)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0030388"(fructose 1,6-bisphosphate metabolic process)|go:"GO:0031430"(M band)|go:"GO:0032496"(response to lipopolysaccharide)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035094"(response to nicotine)|go:"GO:0035686"(sperm fibrous sheath)|go:"GO:0043627"(response to estrogen)|go:"GO:0051289"(protein homotetramerization)|interpro:IPR000741(Fructose-bisphosphate aldolase, class-I)|interpro:IPR013785(Aldolase-type TIM barrel)|interpro:IPR029768|mint:P05065|reactome:R-RNO-114608|reactome:R-RNO-6798695|reactome:R-RNO-70171|reactome:R-RNO-70263|refseq:XP_006230273.1|refseq:NP_001258465.1	-	-	-	figure legend:st1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10116(rat-hippocampus)|taxid:10116(Rattus norvegicus hippocampal neurons)	-	2020/10/30	2020/10/30	rogid:DtE+ZXAZKdCMvUW5K+jXQ5bH07M10116	rogid:dUcYtyffbl8dC/1SD/ZtEtiFyB010116	rigid:zzsc1zNhBb5nwIRPeFpYOKgC3M8	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q5XIE8	uniprotkb:P62630	intact:EBI-15348306|ensembl:ENSRNOP00000023037	intact:EBI-917951|uniprotkb:P20001|uniprotkb:Q5BJW8|uniprotkb:Q64718|uniprotkb:Q78ED4|ensembl:ENSRNOP00000013608	psi-mi:itm2b_rat(display_long)|uniprotkb:Itm2b(gene name)|psi-mi:Itm2b(display_short)|uniprotkb:Immature BRI2(gene name synonym)|uniprotkb:Transmembrane protein BRI(gene name synonym)	psi-mi:ef1a1_rat(display_long)|uniprotkb:Eukaryotic elongation factor 1 A-1(gene name synonym)|uniprotkb:Elongation factor Tu(gene name synonym)|uniprotkb:Eef1a1(gene name)|psi-mi:Eef1a1(display_short)|uniprotkb:Eef1a(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Martins et al. (2018)	imex:IM-28469|pubmed:29476059	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26440627|imex:IM-28469-5	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSRNOG00000016271(gene)|ensembl:ENSRNOT00000023037(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001540"(amyloid-beta binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0010008"(endosome membrane)|go:"GO:0030660"(Golgi-associated vesicle membrane)|go:"GO:0031301"(integral component of organelle membrane)|go:"GO:0042985"(negative regulation of amyloid precursor protein biosynthetic process)|interpro:IPR007084(BRICHOS)|interpro:IPR040145|mint:Q5XIE8|refseq:NP_001006964.1|rgd:620727	rgd:67387|refseq:NP_787032.1|ensembl:ENSRNOG00000009439(gene)|ensembl:ENSRNOT00000013608(transcript)|go:"GO:0000049"(tRNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0003746"(translation elongation factor activity)|go:"GO:0003924"(GTPase activity)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005525"(GTP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006412"(translation)|go:"GO:0006414"(translational elongation)|go:"GO:0007568"(aging)|go:"GO:0010942"(positive regulation of cell death)|go:"GO:0010976"(positive regulation of neuron projection development)|go:"GO:0019900"(kinase binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030864"(cortical actin cytoskeleton)|go:"GO:0032587"(ruffle membrane)|go:"GO:0035690"|go:"GO:0042802"(identical protein binding)|go:"GO:0071364"(cellular response to epidermal growth factor stimulus)|go:"GO:1900022"(regulation of D-erythro-sphingosine kinase activity)|go:"GO:1903427"(negative regulation of reactive oxygen species biosynthetic process)|go:"GO:1990090"(cellular response to nerve growth factor stimulus)|interpro:IPR000795(Protein synthesis factor, GTP-binding)|interpro:IPR004160(Translation elongation factor EFTu/EF1A, C-terminal)|interpro:IPR004161(Translation elongation factor EFTu/EF1A, domain 2)|interpro:IPR004539(Translation elongation factor EF1A, eukaryotic and archaeal)|interpro:IPR009000(Translation elongation and initiation factors/Ribosomal, beta-barrel)|interpro:IPR009001(Translation elongation factor EF1A/initiation factor IF2gamma, C-terminal)|interpro:IPR027417|interpro:IPR031157|mint:P62630|reactome:R-RNO-156842|reactome:R-RNO-3371511|reactome:R-RNO-6798695|reactome:R-RNO-8876725	-	-	-	figure legend:st1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10116(rat-hippocampus)|taxid:10116(Rattus norvegicus hippocampal neurons)	-	2020/10/30	2020/10/30	rogid:DtE+ZXAZKdCMvUW5K+jXQ5bH07M10116	rogid:85G9Uje743KzA02bB/rmKuq2HbU10116	rigid:zzsc1zNhBb5nwIRPeFpYOKgC3M8	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q5XIE8	uniprotkb:O35303	intact:EBI-15348306|ensembl:ENSRNOP00000023037	intact:EBI-1767447|uniprotkb:O35318|uniprotkb:O35319|uniprotkb:O35320|uniprotkb:O35321|uniprotkb:O35322|uniprotkb:O35323|uniprotkb:Q5U2W1|uniprotkb:Q792T7|uniprotkb:Q9R234|uniprotkb:Q9R277|ensembl:ENSRNOP00000002478	psi-mi:itm2b_rat(display_long)|uniprotkb:Itm2b(gene name)|psi-mi:Itm2b(display_short)|uniprotkb:Immature BRI2(gene name synonym)|uniprotkb:Transmembrane protein BRI(gene name synonym)	psi-mi:dnm1l_rat(display_long)|uniprotkb:Dnm1l(gene name)|psi-mi:Dnm1l(display_short)|uniprotkb:Dlp1(gene name synonym)|uniprotkb:Drp1(gene name synonym)|uniprotkb:Dynamin-like protein(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Martins et al. (2018)	imex:IM-28469|pubmed:29476059	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26440627|imex:IM-28469-5	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSRNOG00000016271(gene)|ensembl:ENSRNOT00000023037(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001540"(amyloid-beta binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0010008"(endosome membrane)|go:"GO:0030660"(Golgi-associated vesicle membrane)|go:"GO:0031301"(integral component of organelle membrane)|go:"GO:0042985"(negative regulation of amyloid precursor protein biosynthetic process)|interpro:IPR007084(BRICHOS)|interpro:IPR040145|mint:Q5XIE8|refseq:NP_001006964.1|rgd:620727	rgd:620416|refseq:NP_446107.2|refseq:XP_008767063.1|refseq:XP_008767064.1|refseq:XP_008767065.1|refseq:XP_006248785.1|dip:DIP-29699N|ensembl:ENSRNOG00000001813(gene)|ensembl:ENSRNOT00000002478(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0000266"(mitochondrial fission)|go:"GO:0001836"(release of cytochrome c from mitochondria)|go:"GO:0003374"(dynamin family protein polymerization involved in mitochondrial fission)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005777"(peroxisome)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0005874"(microtubule)|go:"GO:0005903"(brush border)|go:"GO:0006816"(calcium ion transport)|go:"GO:0007005"(mitochondrion organization)|go:"GO:0008017"(microtubule binding)|go:"GO:0008289"(lipid binding)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0010637"(negative regulation of mitochondrial fusion)|go:"GO:0010821"(regulation of mitochondrion organization)|go:"GO:0016020"(membrane)|go:"GO:0016559"(peroxisome fission)|go:"GO:0030276"(clathrin binding)|go:"GO:0030672"(synaptic vesicle membrane)|go:"GO:0030742"(GTP-dependent protein binding)|go:"GO:0031267"(small GTPase binding)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0036466"(synaptic vesicle recycling via endosome)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0043653"(mitochondrial fragmentation involved in apoptotic process)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0048312"(intracellular distribution of mitochondria)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0048488"(synaptic vesicle endocytosis)|go:"GO:0048511"(rhythmic process)|go:"GO:0050714"(positive regulation of protein secretion)|go:"GO:0051259"(protein complex oligomerization)|go:"GO:0051433"(BH2 domain binding)|go:"GO:0060047"(heart contraction)|go:"GO:0061003"(positive regulation of dendritic spine morphogenesis)|go:"GO:0061025"(membrane fusion)|go:"GO:0065003"(protein-containing complex assembly)|go:"GO:0070266"(necroptotic process)|go:"GO:0070584"(mitochondrion morphogenesis)|go:"GO:0070585"(protein localization to mitochondrion)|go:"GO:0071396"(cellular response to lipid)|go:"GO:0090023"(positive regulation of neutrophil chemotaxis)|go:"GO:0090141"(positive regulation of mitochondrial fission)|go:"GO:0090149"(mitochondrial membrane fission)|go:"GO:0090200"(positive regulation of release of cytochrome c from mitochondria)|go:"GO:0090650"(cellular response to oxygen-glucose deprivation)|go:"GO:0098835"(presynaptic endocytic zone membrane)|go:"GO:0099073"(mitochondrion-derived vesicle)|go:"GO:0099503"(secretory vesicle)|go:"GO:1900063"(regulation of peroxisome organization)|go:"GO:1900244"(positive regulation of synaptic vesicle endocytosis)|go:"GO:1903146"(regulation of autophagy of mitochondrion)|go:"GO:1903578"(regulation of ATP metabolic process)|go:"GO:1904579"(cellular response to thapsigargin)|go:"GO:1904666"(regulation of ubiquitin protein ligase activity)|go:"GO:1905395"(response to flavonoid)|go:"GO:1990910"(response to hypobaric hypoxia)|go:"GO:2000302"(positive regulation of synaptic vesicle exocytosis)|go:"GO:2001244"(positive regulation of intrinsic apoptotic signaling pathway)|interpro:IPR000375(Dynamin central region)|interpro:IPR003130(Dynamin GTPase effector)|interpro:IPR019762|interpro:IPR020850|interpro:IPR022812|interpro:IPR027417|interpro:IPR030381|interpro:IPR030556|mint:O35303|reactome:R-RNO-75153|interpro:IPR001401(Dynamin, GTPase region)	-	-	-	figure legend:st1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10116(rat-hippocampus)|taxid:10116(Rattus norvegicus hippocampal neurons)	-	2020/10/30	2020/10/30	rogid:DtE+ZXAZKdCMvUW5K+jXQ5bH07M10116	rogid:HkPGbvyZ4Tb3hJw1EqAya+FIcWg10116	rigid:zzsc1zNhBb5nwIRPeFpYOKgC3M8	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q5XIE8	uniprotkb:P21575	intact:EBI-15348306|ensembl:ENSRNOP00000023037	intact:EBI-80070|ensembl:ENSRNOP00000041582	psi-mi:itm2b_rat(display_long)|uniprotkb:Itm2b(gene name)|psi-mi:Itm2b(display_short)|uniprotkb:Immature BRI2(gene name synonym)|uniprotkb:Transmembrane protein BRI(gene name synonym)	psi-mi:dyn1_rat(display_long)|uniprotkb:Dnm1(gene name)|psi-mi:Dnm1(display_short)|uniprotkb:Dnm(gene name synonym)|uniprotkb:D100(gene name synonym)|uniprotkb:Dynamin, brain(gene name synonym)|uniprotkb:B-dynamin(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Martins et al. (2018)	imex:IM-28469|pubmed:29476059	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26440627|imex:IM-28469-5	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSRNOG00000016271(gene)|ensembl:ENSRNOT00000023037(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001540"(amyloid-beta binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0010008"(endosome membrane)|go:"GO:0030660"(Golgi-associated vesicle membrane)|go:"GO:0031301"(integral component of organelle membrane)|go:"GO:0042985"(negative regulation of amyloid precursor protein biosynthetic process)|interpro:IPR007084(BRICHOS)|interpro:IPR040145|mint:Q5XIE8|refseq:NP_001006964.1|rgd:620727	rgd:71096|refseq:NP_542420.1|ensembl:ENSRNOG00000033835(gene)|ensembl:ENSRNOT00000047921(transcript)|go:"GO:0000266"(mitochondrial fission)|go:"GO:0001917"(photoreceptor inner segment)|go:"GO:0002031"(G protein-coupled receptor internalization)|go:"GO:0003374"(dynamin family protein polymerization involved in mitochondrial fission)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005874"(microtubule)|go:"GO:0005886"(plasma membrane)|go:"GO:0006897"(endocytosis)|go:"GO:0006898"(receptor-mediated endocytosis)|go:"GO:0007032"(endosome organization)|go:"GO:0008017"(microtubule binding)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0014069"(postsynaptic density)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0016020"(membrane)|go:"GO:0016185"(synaptic vesicle budding from presynaptic endocytic zone membrane)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030117"(membrane coat)|go:"GO:0030424"(axon)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0031623"(receptor internalization)|go:"GO:0031749"(D2 dopamine receptor binding)|go:"GO:0031966"(mitochondrial membrane)|go:"GO:0032991"(protein-containing complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0043196"(varicosity)|go:"GO:0044327"(dendritic spine head)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045202"(synapse)|go:"GO:0048488"(synaptic vesicle endocytosis)|go:"GO:0050803"(regulation of synapse structure or activity)|go:"GO:0050804"(modulation of chemical synaptic transmission)|go:"GO:0050998"(nitric-oxide synthase binding)|go:"GO:0061025"(membrane fusion)|go:"GO:0098684"(photoreceptor ribbon synapse)|go:"GO:0098835"(presynaptic endocytic zone membrane)|go:"GO:0098844"(postsynaptic endocytic zone membrane)|go:"GO:0098884"(postsynaptic neurotransmitter receptor internalization)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:1900242"(regulation of synaptic vesicle endocytosis)|go:"GO:1900244"(positive regulation of synaptic vesicle endocytosis)|go:"GO:1901998"(toxin transport)|go:"GO:1903423"(positive regulation of synaptic vesicle recycling)|go:"GO:1904645"(response to amyloid-beta)|interpro:IPR000375(Dynamin central region)|interpro:IPR001401(Dynamin, GTPase region)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR003130(Dynamin GTPase effector)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR019762|interpro:IPR020850|interpro:IPR022812|interpro:IPR027417|interpro:IPR027741|interpro:IPR030381|mint:P21575|rcsb pdb:2AKA|rcsb pdb:3ZVR|reactome:R-RNO-190873|reactome:R-RNO-196025|reactome:R-RNO-2132295|reactome:R-RNO-437239|reactome:R-RNO-8856828|dip:DIP-30978N	-	-	-	figure legend:st1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10116(rat-hippocampus)|taxid:10116(Rattus norvegicus hippocampal neurons)	-	2020/10/30	2020/10/30	rogid:DtE+ZXAZKdCMvUW5K+jXQ5bH07M10116	rogid:x9J/VoMgoDFBHadzOhnN3yhTjfs10116	rigid:zzsc1zNhBb5nwIRPeFpYOKgC3M8	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q5XIE8	uniprotkb:Q6AYH5	intact:EBI-15348306|ensembl:ENSRNOP00000023037	intact:EBI-920539|ensembl:ENSRNOP00000008120	psi-mi:itm2b_rat(display_long)|uniprotkb:Itm2b(gene name)|psi-mi:Itm2b(display_short)|uniprotkb:Immature BRI2(gene name synonym)|uniprotkb:Transmembrane protein BRI(gene name synonym)	psi-mi:dctn2_rat(display_long)|uniprotkb:Dctn2(gene name)|psi-mi:Dctn2(display_short)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Martins et al. (2018)	imex:IM-28469|pubmed:29476059	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26440627|imex:IM-28469-5	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSRNOG00000016271(gene)|ensembl:ENSRNOT00000023037(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001540"(amyloid-beta binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0010008"(endosome membrane)|go:"GO:0030660"(Golgi-associated vesicle membrane)|go:"GO:0031301"(integral component of organelle membrane)|go:"GO:0042985"(negative regulation of amyloid precursor protein biosynthetic process)|interpro:IPR007084(BRICHOS)|interpro:IPR040145|mint:Q5XIE8|refseq:NP_001006964.1|rgd:620727	rgd:1303182|refseq:NP_001004239.1|ensembl:ENSRNOG00000025481(gene)|ensembl:ENSRNOT00000008120(transcript)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0000776"(kinetochore)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005869"(dynactin complex)|go:"GO:0005874"(microtubule)|go:"GO:0007052"(mitotic spindle organization)|go:"GO:0007080"(mitotic metaphase plate congression)|go:"GO:0016020"(membrane)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030286"(dynein complex)|go:"GO:0030426"(growth cone)|go:"GO:0030507"(spectrin binding)|go:"GO:0031982"(vesicle)|go:"GO:0032402"(melanosome transport)|go:"GO:0042802"(identical protein binding)|go:"GO:0071539"(protein localization to centrosome)|interpro:IPR028133|mint:Q6AYH5|reactome:R-RNO-2132295|reactome:R-RNO-2565942|reactome:R-RNO-3371497|reactome:R-RNO-380259|reactome:R-RNO-380270|reactome:R-RNO-380284|reactome:R-RNO-380320|reactome:R-RNO-5620912|reactome:R-RNO-6807878|reactome:R-RNO-6811436|reactome:R-RNO-8854518	-	-	-	figure legend:st1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10116(rat-hippocampus)|taxid:10116(Rattus norvegicus hippocampal neurons)	-	2020/10/30	2020/10/30	rogid:DtE+ZXAZKdCMvUW5K+jXQ5bH07M10116	rogid:B7LyMXi8DNGgOm+GDSigf2eHuE810116	rigid:zzsc1zNhBb5nwIRPeFpYOKgC3M8	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q5XIE8	uniprotkb:Q07266	intact:EBI-15348306|ensembl:ENSRNOP00000023037	intact:EBI-918187|uniprotkb:A5D6R1|uniprotkb:O70205	psi-mi:itm2b_rat(display_long)|uniprotkb:Itm2b(gene name)|psi-mi:Itm2b(display_short)|uniprotkb:Immature BRI2(gene name synonym)|uniprotkb:Transmembrane protein BRI(gene name synonym)	psi-mi:dreb_rat(display_long)|uniprotkb:Dbn1(gene name)|psi-mi:Dbn1(display_short)|uniprotkb:Developmentally-regulated brain protein(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Martins et al. (2018)	imex:IM-28469|pubmed:29476059	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26440627|imex:IM-28469-5	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSRNOG00000016271(gene)|ensembl:ENSRNOT00000023037(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001540"(amyloid-beta binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0010008"(endosome membrane)|go:"GO:0030660"(Golgi-associated vesicle membrane)|go:"GO:0031301"(integral component of organelle membrane)|go:"GO:0042985"(negative regulation of amyloid precursor protein biosynthetic process)|interpro:IPR007084(BRICHOS)|interpro:IPR040145|mint:Q5XIE8|refseq:NP_001006964.1|rgd:620727	rgd:70885|refseq:NP_112286.1|interpro:IPR002108(Actin-binding, cofilin/tropomyosin type)|interpro:IPR028438|mint:Q07266|interpro:IPR029006|refseq:XP_006253719.1|go:"GO:0001701"(in utero embryonic development)|go:"GO:0005522"(profilin binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005921"(gap junction)|go:"GO:0007015"(actin filament organization)|go:"GO:0007283"(spermatogenesis)|go:"GO:0007399"(nervous system development)|go:"GO:0007420"(brain development)|go:"GO:0007568"(aging)|go:"GO:0008092"(cytoskeletal protein binding)|go:"GO:0010643"(cell communication by chemical coupling)|go:"GO:0010644"(cell communication by electrical coupling)|go:"GO:0010811"(positive regulation of cell-substrate adhesion)|go:"GO:0010976"(positive regulation of neuron projection development)|go:"GO:0014069"(postsynaptic density)|go:"GO:0014823"(response to activity)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0016020"(membrane)|go:"GO:0030027"(lamellipodium)|go:"GO:0030175"(filopodium)|go:"GO:0030425"(dendrite)|go:"GO:0030426"(growth cone)|go:"GO:0030427"(site of polarized growth)|go:"GO:0030833"(regulation of actin filament polymerization)|go:"GO:0030864"(cortical actin cytoskeleton)|go:"GO:0031915"(positive regulation of synaptic plasticity)|go:"GO:0032232"(negative regulation of actin filament bundle assembly)|go:"GO:0032279"(asymmetric synapse)|go:"GO:0032507"(maintenance of protein location in cell)|go:"GO:0042493"|go:"GO:0043025"(neuronal cell body)|go:"GO:0043197"(dendritic spine)|go:"GO:0043198"(dendritic shaft)|go:"GO:0044295"(axonal growth cone)|go:"GO:0044308"(axonal spine)|go:"GO:0044309"(neuron spine)|go:"GO:0045211"(postsynaptic membrane)|go:"GO:0045773"(positive regulation of axon extension)|go:"GO:0048286"(lung alveolus development)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0048699"(generation of neurons)|go:"GO:0048812"(neuron projection morphogenesis)|go:"GO:0051015"(actin filament binding)|go:"GO:0051220"(cytoplasmic sequestering of protein)|go:"GO:0051489"(regulation of filopodium assembly)|go:"GO:0060076"(excitatory synapse)|go:"GO:0060134"(prepulse inhibition)|go:"GO:0061003"(positive regulation of dendritic spine morphogenesis)|go:"GO:0061351"(neural precursor cell proliferation)|go:"GO:0071356"(cellular response to tumor necrosis factor)|go:"GO:0071481"(cellular response to X-ray)|go:"GO:0071560"(cellular response to transforming growth factor beta stimulus)|go:"GO:0090327"(negative regulation of locomotion involved in locomotory behavior)|go:"GO:0098828"(modulation of inhibitory postsynaptic potential)|go:"GO:0098871"(postsynaptic actin cytoskeleton)|go:"GO:0098974"(postsynaptic actin cytoskeleton organization)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099524"(postsynaptic cytosol)|go:"GO:0120080"(obsolete negative regulation of microfilament motor activity)|go:"GO:1900026"(positive regulation of substrate adhesion-dependent cell spreading)|go:"GO:1902685"(positive regulation of receptor localization to synapse)|go:"GO:1902737"(dendritic filopodium)|go:"GO:1902897"(regulation of postsynaptic density protein 95 clustering)|go:"GO:1904113"(negative regulation of muscle filament sliding)|go:"GO:2000463"(positive regulation of excitatory postsynaptic potential)|reactome:R-RNO-9013405|reactome:R-RNO-9013407|reactome:R-RNO-9013418|reactome:R-RNO-9013422	-	-	-	figure legend:st1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10116(rat-hippocampus)|taxid:10116(Rattus norvegicus hippocampal neurons)	-	2020/10/30	2020/10/30	rogid:DtE+ZXAZKdCMvUW5K+jXQ5bH07M10116	rogid:ywce7jMZtfDwzFWvAURT5bUsmdY10116	rigid:zzsc1zNhBb5nwIRPeFpYOKgC3M8	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q5XIE8	uniprotkb:P47942	intact:EBI-15348306|ensembl:ENSRNOP00000023037	intact:EBI-917570|intact:EBI-6096016|ensembl:ENSRNOP00000012996	psi-mi:itm2b_rat(display_long)|uniprotkb:Itm2b(gene name)|psi-mi:Itm2b(display_short)|uniprotkb:Immature BRI2(gene name synonym)|uniprotkb:Transmembrane protein BRI(gene name synonym)	psi-mi:dpyl2_rat(display_long)|uniprotkb:Turned on after division 64 kDa protein(gene name synonym)|uniprotkb:Collapsin response mediator protein 2(gene name synonym)|uniprotkb:Dpysl2(gene name)|psi-mi:Dpysl2(display_short)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Martins et al. (2018)	imex:IM-28469|pubmed:29476059	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26440627|imex:IM-28469-5	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSRNOG00000016271(gene)|ensembl:ENSRNOT00000023037(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001540"(amyloid-beta binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0010008"(endosome membrane)|go:"GO:0030660"(Golgi-associated vesicle membrane)|go:"GO:0031301"(integral component of organelle membrane)|go:"GO:0042985"(negative regulation of amyloid precursor protein biosynthetic process)|interpro:IPR007084(BRICHOS)|interpro:IPR040145|mint:Q5XIE8|refseq:NP_001006964.1|rgd:620727	rgd:2517|refseq:NP_001099187.1|ensembl:ENSRNOG00000009625(gene)|ensembl:ENSRNOT00000012996(transcript)|go:"GO:0001975"(response to amphetamine)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005886"(plasma membrane)|go:"GO:0006897"(endocytosis)|go:"GO:0007010"(cytoskeleton organization)|go:"GO:0007411"(axon guidance)|go:"GO:0007420"(brain development)|go:"GO:0008017"(microtubule binding)|go:"GO:0010975"(regulation of neuron projection development)|go:"GO:0014049"(positive regulation of glutamate secretion)|go:"GO:0016810"("hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds")|go:"GO:0019901"(protein kinase binding)|go:"GO:0021510"(spinal cord development)|go:"GO:0021772"(olfactory bulb development)|go:"GO:0030424"(axon)|go:"GO:0030425"(dendrite)|go:"GO:0030426"(growth cone)|go:"GO:0030516"(regulation of axon extension)|go:"GO:0032991"(protein-containing complex)|go:"GO:0042220"(response to cocaine)|go:"GO:0042493"|go:"GO:0042802"(identical protein binding)|go:"GO:0043005"(neuron projection)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043209"(myelin sheath)|go:"GO:0045664"(regulation of neuron differentiation)|go:"GO:0048489"(synaptic vesicle transport)|go:"GO:0098793"(presynapse)|interpro:IPR006680(Amidohydrolase 1)|interpro:IPR011059(Metal-dependent hydrolase, composite)|interpro:IPR011778(D-hydantoinase)|interpro:IPR030615|interpro:IPR032466|mint:P47942|reactome:R-RNO-399956|reactome:R-RNO-437239	-	-	-	figure legend:st1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10116(rat-hippocampus)|taxid:10116(Rattus norvegicus hippocampal neurons)	-	2020/10/30	2020/10/30	rogid:DtE+ZXAZKdCMvUW5K+jXQ5bH07M10116	rogid:97yc8TNEPMcGtGNRLvl+KV+DYr010116	rigid:zzsc1zNhBb5nwIRPeFpYOKgC3M8	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q5XIE8	uniprotkb:P38650	intact:EBI-15348306|ensembl:ENSRNOP00000023037	intact:EBI-349489|uniprotkb:Q63178	psi-mi:itm2b_rat(display_long)|uniprotkb:Itm2b(gene name)|psi-mi:Itm2b(display_short)|uniprotkb:Immature BRI2(gene name synonym)|uniprotkb:Transmembrane protein BRI(gene name synonym)	psi-mi:dyhc1_rat(display_long)|uniprotkb:Dync1h1(gene name)|psi-mi:Dync1h1(display_short)|uniprotkb:Dnch1(gene name synonym)|uniprotkb:Dnec1(gene name synonym)|uniprotkb:Map1c(gene name synonym)|uniprotkb:Dhc1(gene name synonym)|uniprotkb:Dyhc(gene name synonym)|uniprotkb:Cytoplasmic dynein heavy chain 1(gene name synonym)|uniprotkb:Dynein heavy chain, cytosolic(gene name synonym)|uniprotkb:MAP 1C(gene name synonym)|uniprotkb:Dnchc1(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Martins et al. (2018)	imex:IM-28469|pubmed:29476059	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26440627|imex:IM-28469-5	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSRNOG00000016271(gene)|ensembl:ENSRNOT00000023037(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001540"(amyloid-beta binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0010008"(endosome membrane)|go:"GO:0030660"(Golgi-associated vesicle membrane)|go:"GO:0031301"(integral component of organelle membrane)|go:"GO:0042985"(negative regulation of amyloid precursor protein biosynthetic process)|interpro:IPR007084(BRICHOS)|interpro:IPR040145|mint:Q5XIE8|refseq:NP_001006964.1|rgd:620727	rgd:2511|refseq:NP_062099.3|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR004273(Dynein heavy chain)|interpro:IPR024317|interpro:IPR013594(Dynein heavy chain, N-terminal region 1)|interpro:IPR013602(Dynein heavy chain, N-terminal region 2)|interpro:IPR024743|go:"GO:0005737"(cytoplasm)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0002177"(manchette)|go:"GO:0005524"(ATP binding)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005813"(centrosome)|go:"GO:0005868"(cytoplasmic dynein complex)|go:"GO:0005874"(microtubule)|go:"GO:0005881"(cytoplasmic microtubule)|go:"GO:0005938"(cell cortex)|go:"GO:0007018"(microtubule-based movement)|go:"GO:0007097"(nuclear migration)|go:"GO:0007286"(spermatid development)|go:"GO:0008090"(retrograde axonal transport)|go:"GO:0008569"(minus-end-directed microtubule motor activity)|go:"GO:0030175"(filopodium)|go:"GO:0030286"(dynein complex)|go:"GO:0030424"(axon)|go:"GO:0031122"(cytoplasmic microtubule organization)|go:"GO:0032388"(positive regulation of intracellular transport)|go:"GO:0034063"(stress granule assembly)|go:"GO:0043025"(neuronal cell body)|go:"GO:0033962"(P-body assembly)|go:"GO:0045505"(dynein intermediate chain binding)|go:"GO:0051293"(establishment of spindle localization)|go:"GO:0051301"(cell division)|go:"GO:0051959"(dynein light intermediate chain binding)|go:"GO:0060236"(regulation of mitotic spindle organization)|go:"GO:0072382"(minus-end-directed vesicle transport along microtubule)|go:"GO:0090235"(regulation of metaphase plate congression)|go:"GO:0120162"(positive regulation of cold-induced thermogenesis)|go:"GO:1904115"(axon cytoplasm)|go:"GO:1905243"(cellular response to 3,3',5-triiodo-L-thyronine)|go:"GO:1905832"(positive regulation of spindle assembly)|go:"GO:1990090"(cellular response to nerve growth factor stimulus)|reactome:R-RNO-141444|reactome:R-RNO-2132295|reactome:R-RNO-2467813|reactome:R-RNO-2500257|reactome:R-RNO-2565942|reactome:R-RNO-3371497|reactome:R-RNO-380259|reactome:R-RNO-380270|reactome:R-RNO-380284|reactome:R-RNO-380320|reactome:R-RNO-5620912|reactome:R-RNO-5663220|reactome:R-RNO-6798695|reactome:R-RNO-6807878|reactome:R-RNO-6811436|reactome:R-RNO-68877|reactome:R-RNO-8854518|reactome:R-RNO-9646399|reactome:R-RNO-9648025|interpro:IPR042219|interpro:IPR042222|interpro:IPR042228|interpro:IPR027417|mint:P38650|interpro:IPR035699|interpro:IPR035706|interpro:IPR041228|interpro:IPR041466|interpro:IPR041658|interpro:IPR043157|interpro:IPR043160	-	-	-	figure legend:st1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10116(rat-hippocampus)|taxid:10116(Rattus norvegicus hippocampal neurons)	-	2020/10/30	2020/10/30	rogid:DtE+ZXAZKdCMvUW5K+jXQ5bH07M10116	rogid:RxE6eIUsLysOcDObdE+E7cBOC5w10116	rigid:zzsc1zNhBb5nwIRPeFpYOKgC3M8	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q5XIE8	uniprotkb:Q63198	intact:EBI-15348306|ensembl:ENSRNOP00000023037	intact:EBI-2255922|ensembl:ENSRNOP00000006219|ensembl:ENSRNOP00000071355	psi-mi:itm2b_rat(display_long)|uniprotkb:Itm2b(gene name)|psi-mi:Itm2b(display_short)|uniprotkb:Immature BRI2(gene name synonym)|uniprotkb:Transmembrane protein BRI(gene name synonym)	psi-mi:cntn1_rat(display_long)|uniprotkb:Cntn1(gene name)|psi-mi:Cntn1(display_short)|uniprotkb:Neural cell surface protein F3(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Martins et al. (2018)	imex:IM-28469|pubmed:29476059	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26440627|imex:IM-28469-5	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSRNOG00000016271(gene)|ensembl:ENSRNOT00000023037(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001540"(amyloid-beta binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0010008"(endosome membrane)|go:"GO:0030660"(Golgi-associated vesicle membrane)|go:"GO:0031301"(integral component of organelle membrane)|go:"GO:0042985"(negative regulation of amyloid precursor protein biosynthetic process)|interpro:IPR007084(BRICHOS)|interpro:IPR040145|mint:Q5XIE8|refseq:NP_001006964.1|rgd:620727	refseq:XP_017450105.1|rgd:621300|refseq:NP_476459.1|refseq:XP_006242239.1|dip:DIP-53082N|ensembl:ENSRNOG00000004438(gene)|ensembl:ENSRNOT00000006219(transcript)|ensembl:ENSRNOT00000080621(transcript)|go:"GO:0005886"(plasma membrane)|go:"GO:0007155"(cell adhesion)|go:"GO:0007219"(Notch signaling pathway)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010765"(positive regulation of sodium ion transport)|go:"GO:0010976"(positive regulation of neuron projection development)|go:"GO:0021549"(cerebellum development)|go:"GO:0030246"(carbohydrate binding)|go:"GO:0031175"(neuron projection development)|go:"GO:0045121"(membrane raft)|go:"GO:0050731"(positive regulation of peptidyl-tyrosine phosphorylation)|go:"GO:0099025"(anchored component of postsynaptic membrane)|go:"GO:0099026"(anchored component of presynaptic membrane)|interpro:IPR003598(Immunoglobulin subtype 2)|interpro:IPR003599(Immunoglobulin subtype)|interpro:IPR003961(Fibronectin, type III)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR013098(Immunoglobulin I-set)|interpro:IPR013151(Immunoglobulin)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR036116|interpro:IPR036179|interpro:IPR036992|mint:Q63198	-	-	-	figure legend:st1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10116(rat-hippocampus)|taxid:10116(Rattus norvegicus hippocampal neurons)	-	2020/10/30	2020/10/30	rogid:DtE+ZXAZKdCMvUW5K+jXQ5bH07M10116	rogid:xwArPbuIT63LL9S/vyET64hKfUk10116	rigid:zzsc1zNhBb5nwIRPeFpYOKgC3M8	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q5XIE8	uniprotkb:P08082	intact:EBI-15348306|ensembl:ENSRNOP00000023037	intact:EBI-10055575|ensembl:ENSRNOP00000023651	psi-mi:itm2b_rat(display_long)|uniprotkb:Itm2b(gene name)|psi-mi:Itm2b(display_short)|uniprotkb:Immature BRI2(gene name synonym)|uniprotkb:Transmembrane protein BRI(gene name synonym)	psi-mi:clcb_rat(display_long)|uniprotkb:Cltb(gene name)|psi-mi:Cltb(display_short)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Martins et al. (2018)	imex:IM-28469|pubmed:29476059	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26440627|imex:IM-28469-5	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSRNOG00000016271(gene)|ensembl:ENSRNOT00000023037(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001540"(amyloid-beta binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0010008"(endosome membrane)|go:"GO:0030660"(Golgi-associated vesicle membrane)|go:"GO:0031301"(integral component of organelle membrane)|go:"GO:0042985"(negative regulation of amyloid precursor protein biosynthetic process)|interpro:IPR007084(BRICHOS)|interpro:IPR040145|mint:Q5XIE8|refseq:NP_001006964.1|rgd:620727	rgd:621353|refseq:NP_446287.1|refseq:XP_006253657.1|ensembl:ENSRNOG00000017506(gene)|ensembl:ENSRNOT00000023651(transcript)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005326"(neurotransmitter transmembrane transporter activity)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006836"(neurotransmitter transport)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0007269"(neurotransmitter secretion)|go:"GO:0016183"(synaptic vesicle coating)|go:"GO:0030118"(clathrin coat)|go:"GO:0030125"(clathrin vesicle coat)|go:"GO:0030130"(clathrin coat of trans-Golgi network vesicle)|go:"GO:0030132"(clathrin coat of coated pit)|go:"GO:0030672"(synaptic vesicle membrane)|go:"GO:0032050"(clathrin heavy chain binding)|go:"GO:0042277"(peptide binding)|go:"GO:0048268"(clathrin coat assembly)|go:"GO:0060170"(ciliary membrane)|go:"GO:0072583"(clathrin-dependent endocytosis)|go:"GO:0098835"(presynaptic endocytic zone membrane)|go:"GO:0099631"(postsynaptic endocytic zone cytoplasmic component)|interpro:IPR000996(Clathrin light chain)|mint:P08082|reactome:R-RNO-190873|reactome:R-RNO-196025|reactome:R-RNO-432720|reactome:R-RNO-5099900|reactome:R-RNO-5140745|reactome:R-RNO-8856825|reactome:R-RNO-8856828	-	-	-	figure legend:st1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10116(rat-hippocampus)|taxid:10116(Rattus norvegicus hippocampal neurons)	-	2020/10/30	2020/10/30	rogid:DtE+ZXAZKdCMvUW5K+jXQ5bH07M10116	rogid:0DE/O9BdSzs0dUd4wVWHN8uVaGU10116	rigid:zzsc1zNhBb5nwIRPeFpYOKgC3M8	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q5XIE8	uniprotkb:P08081	intact:EBI-15348306|ensembl:ENSRNOP00000023037	intact:EBI-916140|ensembl:ENSRNOP00000019737	psi-mi:itm2b_rat(display_long)|uniprotkb:Itm2b(gene name)|psi-mi:Itm2b(display_short)|uniprotkb:Immature BRI2(gene name synonym)|uniprotkb:Transmembrane protein BRI(gene name synonym)	psi-mi:clca_rat(display_long)|uniprotkb:Clta(gene name)|psi-mi:Clta(display_short)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Martins et al. (2018)	imex:IM-28469|pubmed:29476059	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26440627|imex:IM-28469-5	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSRNOG00000016271(gene)|ensembl:ENSRNOT00000023037(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001540"(amyloid-beta binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0010008"(endosome membrane)|go:"GO:0030660"(Golgi-associated vesicle membrane)|go:"GO:0031301"(integral component of organelle membrane)|go:"GO:0042985"(negative regulation of amyloid precursor protein biosynthetic process)|interpro:IPR007084(BRICHOS)|interpro:IPR040145|mint:Q5XIE8|refseq:NP_001006964.1|rgd:620727	ensembl:ENSRNOG00000014635(gene)|ensembl:ENSRNOT00000019737(transcript)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005819"(spindle)|go:"GO:0005886"(plasma membrane)|go:"GO:0005905"(clathrin-coated pit)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006897"(endocytosis)|go:"GO:0007049"(cell cycle)|go:"GO:0030118"(clathrin coat)|go:"GO:0030125"(clathrin vesicle coat)|go:"GO:0030130"(clathrin coat of trans-Golgi network vesicle)|go:"GO:0030132"(clathrin coat of coated pit)|go:"GO:0030136"(clathrin-coated vesicle)|go:"GO:0030669"(clathrin-coated endocytic vesicle membrane)|go:"GO:0030672"(synaptic vesicle membrane)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0032050"(clathrin heavy chain binding)|go:"GO:0042277"(peptide binding)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0048268"(clathrin coat assembly)|go:"GO:0051020"(GTPase binding)|go:"GO:0051301"(cell division)|go:"GO:0071439"(clathrin complex)|go:"GO:0072583"(clathrin-dependent endocytosis)|go:"GO:0098835"(presynaptic endocytic zone membrane)|go:"GO:0098843"(postsynaptic endocytic zone)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099631"(postsynaptic endocytic zone cytoplasmic component)|interpro:IPR000996(Clathrin light chain)|mint:P08081|reactome:R-RNO-177504|reactome:R-RNO-190873|reactome:R-RNO-196025|reactome:R-RNO-2132295|reactome:R-RNO-432720|reactome:R-RNO-432722|reactome:R-RNO-437239|reactome:R-RNO-5099900|reactome:R-RNO-5140745|reactome:R-RNO-8856825|reactome:R-RNO-8856828|reactome:R-RNO-8866427|reactome:R-RNO-8964038|rgd:70919|refseq:NP_114180.1|refseq:XP_006238166.1|refseq:XP_006238168.1|dip:DIP-36947N	-	-	-	figure legend:st1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10116(rat-hippocampus)|taxid:10116(Rattus norvegicus hippocampal neurons)	-	2020/10/30	2020/10/30	rogid:DtE+ZXAZKdCMvUW5K+jXQ5bH07M10116	rogid:josnOtPnIhM+WCMg+3/jsbSvdec10116	rigid:zzsc1zNhBb5nwIRPeFpYOKgC3M8	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q5XIE8	uniprotkb:P11442	intact:EBI-15348306|ensembl:ENSRNOP00000023037	intact:EBI-397997	psi-mi:itm2b_rat(display_long)|uniprotkb:Itm2b(gene name)|psi-mi:Itm2b(display_short)|uniprotkb:Immature BRI2(gene name synonym)|uniprotkb:Transmembrane protein BRI(gene name synonym)	psi-mi:clh1_rat(display_long)|uniprotkb:Cltc(gene name)|psi-mi:Cltc(display_short)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Martins et al. (2018)	imex:IM-28469|pubmed:29476059	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26440627|imex:IM-28469-5	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSRNOG00000016271(gene)|ensembl:ENSRNOT00000023037(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001540"(amyloid-beta binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0010008"(endosome membrane)|go:"GO:0030660"(Golgi-associated vesicle membrane)|go:"GO:0031301"(integral component of organelle membrane)|go:"GO:0042985"(negative regulation of amyloid precursor protein biosynthetic process)|interpro:IPR007084(BRICHOS)|interpro:IPR040145|mint:Q5XIE8|refseq:NP_001006964.1|rgd:620727	rgd:2364|refseq:NP_062172.1|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0003725"(double-stranded RNA binding)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005819"(spindle)|go:"GO:0005829"(cytosol)|go:"GO:0005905"(clathrin-coated pit)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006898"(receptor-mediated endocytosis)|go:"GO:0006914"(autophagy)|go:"GO:0007030"(Golgi organization)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0016020"(membrane)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030117"(membrane coat)|go:"GO:0030118"(clathrin coat)|go:"GO:0030130"(clathrin coat of trans-Golgi network vesicle)|go:"GO:0030132"(clathrin coat of coated pit)|go:"GO:0030136"(clathrin-coated vesicle)|go:"GO:0030315"(T-tubule)|go:"GO:0030506"(ankyrin binding)|go:"GO:0030669"(clathrin-coated endocytic vesicle membrane)|go:"GO:0031072"(heat shock protein binding)|go:"GO:0031623"(receptor internalization)|go:"GO:0032051"(clathrin light chain binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033572"(transferrin transport)|go:"GO:0042147"(retrograde transport, endosome to Golgi)|go:"GO:0042277"(peptide binding)|go:"GO:0042383"(sarcolemma)|go:"GO:0042470"(melanosome)|go:"GO:0043195"(terminal bouton)|go:"GO:0045334"(clathrin-coated endocytic vesicle)|interpro:IPR015348(Clathrin, heavy chain, linker, core motif)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR016025(Clathrin, heavy chain, linker and propeller)|go:"GO:0048268"(clathrin coat assembly)|go:"GO:0048488"(synaptic vesicle endocytosis)|go:"GO:0050750"(low-density lipoprotein particle receptor binding)|go:"GO:0060236"(regulation of mitotic spindle organization)|go:"GO:0071439"(clathrin complex)|go:"GO:0072583"(clathrin-dependent endocytosis)|go:"GO:0097718"(disordered domain specific binding)|go:"GO:0098684"(photoreceptor ribbon synapse)|go:"GO:0098835"(presynaptic endocytic zone membrane)|go:"GO:0098850"(extrinsic component of synaptic vesicle membrane)|go:"GO:0150093"(amyloid-beta clearance by transcytosis)|go:"GO:1900126"(negative regulation of hyaluronan biosynthetic process)|go:"GO:1903077"(negative regulation of protein localization to plasma membrane)|go:"GO:1990381"(ubiquitin-specific protease binding)|go:"GO:1990498"(mitotic spindle microtubule)|interpro:IPR000547(Clathrin, heavy chain/VPS, 7-fold repeat)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR016341(Clathrin, heavy chain)|interpro:IPR022365|rcsb pdb:1BPO|rcsb pdb:1C9I|rcsb pdb:1C9L|reactome:R-RNO-177504|reactome:R-RNO-190873|reactome:R-RNO-196025|reactome:R-RNO-2132295|reactome:R-RNO-432720|reactome:R-RNO-432722|reactome:R-RNO-437239|reactome:R-RNO-5099900|reactome:R-RNO-5140745|reactome:R-RNO-8856825|reactome:R-RNO-8856828|reactome:R-RNO-8866427|reactome:R-RNO-8964038|reactome:R-RNO-9013420|reactome:R-RNO-9013424|mint:P11442|dip:DIP-36966N	-	-	-	figure legend:st1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10116(rat-hippocampus)|taxid:10116(Rattus norvegicus hippocampal neurons)	-	2020/10/30	2020/10/30	rogid:DtE+ZXAZKdCMvUW5K+jXQ5bH07M10116	rogid:IRKdzbAIpw7D7qHqyxStNyfI38g10116	rigid:zzsc1zNhBb5nwIRPeFpYOKgC3M8	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q5XIE8	uniprotkb:Q05140	intact:EBI-15348306|ensembl:ENSRNOP00000023037	intact:EBI-1374805	psi-mi:itm2b_rat(display_long)|uniprotkb:Itm2b(gene name)|psi-mi:Itm2b(display_short)|uniprotkb:Immature BRI2(gene name synonym)|uniprotkb:Transmembrane protein BRI(gene name synonym)	psi-mi:ap180_rat(display_long)|uniprotkb:Snap91(gene name)|psi-mi:Snap91(display_short)|uniprotkb:Clathrin coat-associated protein AP180(gene name synonym)|uniprotkb:91 kDa synaptosomal-associated protein(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Martins et al. (2018)	imex:IM-28469|pubmed:29476059	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26440627|imex:IM-28469-5	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSRNOG00000016271(gene)|ensembl:ENSRNOT00000023037(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001540"(amyloid-beta binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0010008"(endosome membrane)|go:"GO:0030660"(Golgi-associated vesicle membrane)|go:"GO:0031301"(integral component of organelle membrane)|go:"GO:0042985"(negative regulation of amyloid precursor protein biosynthetic process)|interpro:IPR007084(BRICHOS)|interpro:IPR040145|mint:Q5XIE8|refseq:NP_001006964.1|rgd:620727	rgd:69276|refseq:NP_113916.1|interpro:IPR011417(ANTH)|interpro:IPR014712(Clathrin adaptor, phosphoinositide-binding, GAT-like)|interpro:IPR008942(ENTH/VHS)|interpro:IPR013809(Epsin-like, N-terminal)|mint:Q05140|go:"GO:0072583"(clathrin-dependent endocytosis)|go:"GO:0098685"(Schaffer collateral - CA1 synapse)|go:"GO:0098688"(parallel fiber to Purkinje cell synapse)|go:"GO:0098830"(presynaptic endosome)|go:"GO:0098833"(presynaptic endocytic zone)|go:"GO:0098894"(extrinsic component of presynaptic endocytic zone membrane)|go:"GO:1900242"(regulation of synaptic vesicle endocytosis)|go:"GO:1900244"(positive regulation of synaptic vesicle endocytosis)|go:"GO:1900275"(negative regulation of phospholipase C activity)|go:"GO:1904006"(negative regulation of phospholipase D activity)|go:"GO:1905445"(positive regulation of clathrin coat assembly)|go:"GO:2000331"(regulation of terminal button organization)|go:"GO:2000369"(regulation of clathrin-dependent endocytosis)|go:"GO:2000809"(positive regulation of synaptic vesicle clustering)|reactome:R-RNO-8856825|reactome:R-RNO-8856828|go:"GO:0000149"(SNARE binding)|go:"GO:0000822"(inositol hexakisphosphate binding)|go:"GO:0005545"(1-phosphatidylinositol binding)|go:"GO:0005546"(phosphatidylinositol-4,5-bisphosphate binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005905"(clathrin-coated pit)|go:"GO:0006900"(vesicle budding from membrane)|go:"GO:0007163"(establishment or maintenance of cell polarity)|go:"GO:0007268"(chemical synaptic transmission)|go:"GO:0007269"(neurotransmitter secretion)|go:"GO:0007409"(axonogenesis)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0014069"(postsynaptic density)|go:"GO:0015031"(protein transport)|go:"GO:0016185"(synaptic vesicle budding from presynaptic endocytic zone membrane)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030100"(regulation of endocytosis)|go:"GO:0030136"(clathrin-coated vesicle)|go:"GO:0031313"(extrinsic component of endosome membrane)|go:"GO:0032050"(clathrin heavy chain binding)|go:"GO:0035615"(clathrin adaptor activity)|go:"GO:0042169"(SH2 domain binding)|go:"GO:0042734"(presynaptic membrane)|go:"GO:0043005"(neuron projection)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043195"(terminal bouton)|go:"GO:0043274"(phospholipase binding)|go:"GO:0043679"(axon terminus)|go:"GO:0045211"(postsynaptic membrane)|go:"GO:0048268"(clathrin coat assembly)|go:"GO:0048488"(synaptic vesicle endocytosis)|go:"GO:0048666"(neuron development)|go:"GO:0048787"(presynaptic active zone membrane)|go:"GO:0050772"(positive regulation of axonogenesis)|go:"GO:0051223"(regulation of protein transport)|go:"GO:0051899"(membrane depolarization)|interpro:IPR030428	-	-	-	figure legend:st1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10116(rat-hippocampus)|taxid:10116(Rattus norvegicus hippocampal neurons)	-	2020/10/30	2020/10/30	rogid:DtE+ZXAZKdCMvUW5K+jXQ5bH07M10116	rogid:LXxIlR8jL+mLJ94McATz+sj4xF410116	rigid:zzsc1zNhBb5nwIRPeFpYOKgC3M8	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q5XIE8	uniprotkb:B5D5N9	intact:EBI-15348306|ensembl:ENSRNOP00000023037	intact:EBI-15186164|ensembl:ENSRNOP00000015127|uniprotkb:B5D5P0	psi-mi:itm2b_rat(display_long)|uniprotkb:Itm2b(gene name)|psi-mi:Itm2b(display_short)|uniprotkb:Immature BRI2(gene name synonym)|uniprotkb:Transmembrane protein BRI(gene name synonym)	psi-mi:ctr2_rat(display_long)|uniprotkb:Low affinity cationic amino acid transporter 2(gene name synonym)|uniprotkb:Solute carrier family 7 member 2(gene name synonym)|uniprotkb:Slc7a2(gene name)|psi-mi:Slc7a2(display_short)|uniprotkb:Atrc2(gene name synonym)|uniprotkb:Cat2(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Martins et al. (2018)	imex:IM-28469|pubmed:29476059	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26440627|imex:IM-28469-5	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSRNOG00000016271(gene)|ensembl:ENSRNOT00000023037(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001540"(amyloid-beta binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0010008"(endosome membrane)|go:"GO:0030660"(Golgi-associated vesicle membrane)|go:"GO:0031301"(integral component of organelle membrane)|go:"GO:0042985"(negative regulation of amyloid precursor protein biosynthetic process)|interpro:IPR007084(BRICHOS)|interpro:IPR040145|mint:Q5XIE8|refseq:NP_001006964.1|rgd:620727	ensembl:ENSRNOT00000015127(transcript)|go:"GO:0000064"(L-ornithine transmembrane transporter activity)|go:"GO:0002537"(nitric oxide production involved in inflammatory response)|go:"GO:0005886"(plasma membrane)|go:"GO:0006809"(nitric oxide biosynthetic process)|go:"GO:0006865"(amino acid transport)|go:"GO:0015171"(amino acid transmembrane transporter activity)|ensembl:ENSRNOG00000011016(gene)|go:"GO:0015181"|go:"GO:0015189"(L-lysine transmembrane transporter activity)|go:"GO:0015809"|go:"GO:0016021"(integral component of membrane)|go:"GO:0030054"(cell junction)|go:"GO:0042116"(macrophage activation)|go:"GO:0043030"(regulation of macrophage activation)|go:"GO:0050727"(regulation of inflammatory response)|go:"GO:0061459"(L-arginine transmembrane transporter activity)|go:"GO:0097638"(L-arginine import across plasma membrane)|go:"GO:1902023"|go:"GO:1903352"(L-ornithine transmembrane transport)|interpro:IPR002293(Amino acid/polyamine transporter I)|interpro:IPR004755(Cationic amino acid transport permease)|interpro:IPR029485|mint:B5D5N9|reactome:R-RNO-352230|refseq:NP_001128158.1|refseq:NP_072141.2|rgd:68387	-	-	-	figure legend:st1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10116(rat-hippocampus)|taxid:10116(Rattus norvegicus hippocampal neurons)	-	2020/10/30	2020/10/30	rogid:DtE+ZXAZKdCMvUW5K+jXQ5bH07M10116	rogid:rhzF/yjx/SYNEDYtsLMV+3kXpEU10116	rigid:zzsc1zNhBb5nwIRPeFpYOKgC3M8	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q5XIE8	uniprotkb:P15999	intact:EBI-15348306|ensembl:ENSRNOP00000023037	intact:EBI-916646|uniprotkb:Q6P753	psi-mi:itm2b_rat(display_long)|uniprotkb:Itm2b(gene name)|psi-mi:Itm2b(display_short)|uniprotkb:Immature BRI2(gene name synonym)|uniprotkb:Transmembrane protein BRI(gene name synonym)	psi-mi:atpa_rat(display_long)|uniprotkb:Atp5f1a(gene name)|psi-mi:Atp5f1a(display_short)|uniprotkb:ATP synthase F1 subunit alpha(gene name synonym)|uniprotkb:Atp5a1(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Martins et al. (2018)	imex:IM-28469|pubmed:29476059	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26440627|imex:IM-28469-5	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSRNOG00000016271(gene)|ensembl:ENSRNOT00000023037(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001540"(amyloid-beta binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0010008"(endosome membrane)|go:"GO:0030660"(Golgi-associated vesicle membrane)|go:"GO:0031301"(integral component of organelle membrane)|go:"GO:0042985"(negative regulation of amyloid precursor protein biosynthetic process)|interpro:IPR007084(BRICHOS)|interpro:IPR040145|mint:Q5XIE8|refseq:NP_001006964.1|rgd:620727	rgd:619993|refseq:NP_075581.1|interpro:IPR020003|interpro:IPR005294(ATPase, F1 complex, alpha subunit)|interpro:IPR023366|interpro:IPR000793(ATPase, F1/V1/A1 complex, alpha/beta subunit, C-terminal)|interpro:IPR004100(ATPase, F1/V1/A1 complex, alpha/beta subunit, N-terminal)|interpro:IPR000194(ATPase, F1/V1/A1 complex, alpha/beta subunit, nucleotide-binding)|interpro:IPR033732|interpro:IPR027417|mint:P15999|interpro:IPR038376|interpro:IPR036121|go:"GO:0000275"("mitochondrial proton-transporting ATP synthase complex, catalytic sector F(1)")|go:"GO:0001937"(negative regulation of endothelial cell proliferation)|go:"GO:0002020"(protease binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005753"(mitochondrial proton-transporting ATP synthase complex)|go:"GO:0005754"(mitochondrial proton-transporting ATP synthase, catalytic core)|go:"GO:0005886"(plasma membrane)|go:"GO:0006629"(lipid metabolic process)|go:"GO:0006754"(ATP biosynthetic process)|go:"GO:0006915"(apoptotic process)|go:"GO:0007568"(aging)|go:"GO:0009986"(cell surface)|go:"GO:0014850"(response to muscle activity)|go:"GO:0015986"(ATP synthesis coupled proton transport)|go:"GO:0016020"(membrane)|go:"GO:0042288"(MHC class I protein binding)|go:"GO:0042776"(mitochondrial ATP synthesis coupled proton transport)|go:"GO:0043531"(ADP binding)|go:"GO:0043532"(angiostatin binding)|go:"GO:0043536"(positive regulation of blood vessel endothelial cell migration)|go:"GO:0045121"(membrane raft)|go:"GO:0045259"(proton-transporting ATP synthase complex)|go:"GO:0045261"("proton-transporting ATP synthase complex, catalytic core F(1)")|go:"GO:0045471"(response to ethanol)|go:"GO:0046034"(ATP metabolic process)|go:"GO:0046933"(proton-transporting ATP synthase activity, rotational mechanism)|go:"GO:0071549"(cellular response to dexamethasone stimulus)|go:"GO:0071732"(cellular response to nitric oxide)|rcsb pdb:1MAB|rcsb pdb:2F43	-	-	-	figure legend:st1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10116(rat-hippocampus)|taxid:10116(Rattus norvegicus hippocampal neurons)	-	2020/10/30	2020/10/30	rogid:DtE+ZXAZKdCMvUW5K+jXQ5bH07M10116	rogid:Jkbhz0cHR3egHpKo/n1Ex4EbnUI10116	rigid:zzsc1zNhBb5nwIRPeFpYOKgC3M8	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q5XIE8	uniprotkb:P19511	intact:EBI-15348306|ensembl:ENSRNOP00000023037	intact:EBI-2255901|ensembl:ENSRNOP00000021920|ensembl:ENSRNOP00000065147	psi-mi:itm2b_rat(display_long)|uniprotkb:Itm2b(gene name)|psi-mi:Itm2b(display_short)|uniprotkb:Immature BRI2(gene name synonym)|uniprotkb:Transmembrane protein BRI(gene name synonym)	psi-mi:at5f1_rat(display_long)|uniprotkb:Atp5pb(gene name)|psi-mi:Atp5pb(display_short)|uniprotkb:ATP synthase peripheral stalk-membrane subunit b(gene name synonym)|uniprotkb:ATP synthase subunit b(gene name synonym)|uniprotkb:Atp5f(gene name synonym)|uniprotkb:Atp5f1(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Martins et al. (2018)	imex:IM-28469|pubmed:29476059	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26440627|imex:IM-28469-5	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSRNOG00000016271(gene)|ensembl:ENSRNOT00000023037(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001540"(amyloid-beta binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0010008"(endosome membrane)|go:"GO:0030660"(Golgi-associated vesicle membrane)|go:"GO:0031301"(integral component of organelle membrane)|go:"GO:0042985"(negative regulation of amyloid precursor protein biosynthetic process)|interpro:IPR007084(BRICHOS)|interpro:IPR040145|mint:Q5XIE8|refseq:NP_001006964.1|rgd:620727	rgd:620041|refseq:NP_599192.1|refseq:XP_003749420.1|ensembl:ENSRNOG00000016000(gene)|ensembl:ENSRNOG00000046299(gene)|ensembl:ENSRNOT00000021920(transcript)|ensembl:ENSRNOT00000075083(transcript)|go:"GO:0000276"("mitochondrial proton-transporting ATP synthase complex, coupling factor F(o)")|go:"GO:0005753"(mitochondrial proton-transporting ATP synthase complex)|go:"GO:0015078"(proton transmembrane transporter activity)|go:"GO:0015986"(ATP synthesis coupled proton transport)|go:"GO:0042776"(mitochondrial ATP synthesis coupled proton transport)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0046034"(ATP metabolic process)|go:"GO:0071456"(cellular response to hypoxia)|interpro:IPR008688(ATPase, F0 complex, subunit B, mitochondrial)|interpro:IPR013837(ATPase, F0 complex subunit B, mitochondrial, metazoa)|mint:P19511|reactome:R-RNO-163210|reactome:R-RNO-8949613	-	-	-	figure legend:st1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10116(rat-hippocampus)|taxid:10116(Rattus norvegicus hippocampal neurons)	-	2020/10/30	2020/10/30	rogid:DtE+ZXAZKdCMvUW5K+jXQ5bH07M10116	rogid:QAiktmxMbugxEHz2O+zYw8oHMPk10116	rigid:zzsc1zNhBb5nwIRPeFpYOKgC3M8	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q5XIE8	uniprotkb:P0C1X8	intact:EBI-15348306|ensembl:ENSRNOP00000023037	intact:EBI-26439554	psi-mi:itm2b_rat(display_long)|uniprotkb:Itm2b(gene name)|psi-mi:Itm2b(display_short)|uniprotkb:Immature BRI2(gene name synonym)|uniprotkb:Transmembrane protein BRI(gene name synonym)	psi-mi:aak1_rat(display_long)|uniprotkb:Aak1(gene name)|psi-mi:Aak1(display_short)|uniprotkb:Adaptor-associated kinase 1(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Martins et al. (2018)	imex:IM-28469|pubmed:29476059	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26440627|imex:IM-28469-5	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSRNOG00000016271(gene)|ensembl:ENSRNOT00000023037(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001540"(amyloid-beta binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0010008"(endosome membrane)|go:"GO:0030660"(Golgi-associated vesicle membrane)|go:"GO:0031301"(integral component of organelle membrane)|go:"GO:0042985"(negative regulation of amyloid precursor protein biosynthetic process)|interpro:IPR007084(BRICHOS)|interpro:IPR040145|mint:Q5XIE8|refseq:NP_001006964.1|rgd:620727	go:"GO:0005905"(clathrin-coated pit)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0006897"(endocytosis)|go:"GO:0019897"(extrinsic component of plasma membrane)|go:"GO:0031252"(cell leading edge)|go:"GO:0032880"(regulation of protein localization)|go:"GO:0035612"(AP-2 adaptor complex binding)|go:"GO:0043195"(terminal bouton)|go:"GO:0045747"(positive regulation of Notch signaling pathway)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0005112"(Notch binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0050821"(protein stabilization)|go:"GO:0071439"(clathrin complex)|go:"GO:0098793"(presynapse)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:2000369"(regulation of clathrin-dependent endocytosis)|reactome:R-RNO-8856825|reactome:R-RNO-8856828|mint:P0C1X8|interpro:IPR011009(Protein kinase-like)|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|rgd:1305520	-	-	-	figure legend:st1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10116(rat-hippocampus)|taxid:10116(Rattus norvegicus hippocampal neurons)	-	2020/10/30	2020/10/30	rogid:DtE+ZXAZKdCMvUW5K+jXQ5bH07M10116	rogid:C6WcpCL38oyfBD2aH90f1Y390so10116	rigid:zzsc1zNhBb5nwIRPeFpYOKgC3M8	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q5XIE8	uniprotkb:P84092	intact:EBI-15348306|ensembl:ENSRNOP00000023037	intact:EBI-297693|uniprotkb:P53679|uniprotkb:P20172|ensembl:ENSRNOP00000070202	psi-mi:itm2b_rat(display_long)|uniprotkb:Itm2b(gene name)|psi-mi:Itm2b(display_short)|uniprotkb:Immature BRI2(gene name synonym)|uniprotkb:Transmembrane protein BRI(gene name synonym)	psi-mi:ap2m1_rat(display_long)|uniprotkb:Adaptor protein complex AP-2 subunit mu(gene name synonym)|uniprotkb:AP-2 mu chain(gene name synonym)|uniprotkb:Ap2m1(gene name)|psi-mi:Ap2m1(display_short)|uniprotkb:Mu2-adaptin(gene name synonym)|uniprotkb:Plasma membrane adaptor AP-2 50 kDa protein(gene name synonym)|uniprotkb:Clathrin coat assembly protein AP50(gene name synonym)|uniprotkb:Clathrin coat-associated protein AP50(gene name synonym)|uniprotkb:Clathrin assembly protein complex 2 mu medium chain(gene name synonym)|uniprotkb:Adaptor-related protein complex 2 subunit mu(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Martins et al. (2018)	imex:IM-28469|pubmed:29476059	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26440627|imex:IM-28469-5	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSRNOG00000016271(gene)|ensembl:ENSRNOT00000023037(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001540"(amyloid-beta binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0010008"(endosome membrane)|go:"GO:0030660"(Golgi-associated vesicle membrane)|go:"GO:0031301"(integral component of organelle membrane)|go:"GO:0042985"(negative regulation of amyloid precursor protein biosynthetic process)|interpro:IPR007084(BRICHOS)|interpro:IPR040145|mint:Q5XIE8|refseq:NP_001006964.1|rgd:620727	go:"GO:0098794"(postsynapse)|go:"GO:0098884"(postsynaptic neurotransmitter receptor internalization)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:1900244"(positive regulation of synaptic vesicle endocytosis)|go:"GO:1903077"(negative regulation of protein localization to plasma membrane)|interpro:IPR001392(Clathrin adaptor, mu subunit)|interpro:IPR011012(Longin-like)|interpro:IPR018240|interpro:IPR022775|interpro:IPR028565|interpro:IPR036168|interpro:IPR043512|interpro:IPR043532|mint:P84092|rcsb pdb:1BW8|rcsb pdb:1BXX|rcsb pdb:1HES|rcsb pdb:1I31|rcsb pdb:2BP5|rcsb pdb:2JKR|rcsb pdb:2JKT|rcsb pdb:2PR9|rcsb pdb:2VGL|rcsb pdb:2XA7|rcsb pdb:3H85|rcsb pdb:3ML6|rcsb pdb:4UQI|rcsb pdb:5C7Z|rcsb pdb:5FPI|rcsb pdb:5WRK|go:"GO:0097718"(disordered domain specific binding)|rcsb pdb:5WRL|rcsb pdb:5WRM|rcsb pdb:6QH5|rcsb pdb:6QH6|rcsb pdb:6RH6|rcsb pdb:6YAE|rcsb pdb:6YAF|rcsb pdb:6YAH|reactome:R-RNO-177504|reactome:R-RNO-190873|reactome:R-RNO-196025|reactome:R-RNO-2132295|reactome:R-RNO-416993|reactome:R-RNO-437239|reactome:R-RNO-5099900|reactome:R-RNO-5140745|reactome:R-RNO-8856825|reactome:R-RNO-8856828|reactome:R-RNO-8866427|reactome:R-RNO-8964038|ensembl:ENSRNOG00000001709(gene)|ensembl:ENSRNOT00000088821(transcript)|go:"GO:0002092"(positive regulation of receptor internalization)|go:"GO:0005048"(signal sequence binding)|go:"GO:0005886"(plasma membrane)|go:"GO:0005905"(clathrin-coated pit)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006897"(endocytosis)|go:"GO:0006900"(vesicle budding from membrane)|go:"GO:0008289"(lipid binding)|go:"GO:0016192"(vesicle-mediated transport)|go:"GO:0030122"(AP-2 adaptor complex)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0031623"(receptor internalization)|go:"GO:0035615"(clathrin adaptor activity)|go:"GO:0043195"(terminal bouton)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0048488"(synaptic vesicle endocytosis)|go:"GO:0050750"(low-density lipoprotein particle receptor binding)|go:"GO:0065003"(protein-containing complex assembly)|go:"GO:0072583"(clathrin-dependent endocytosis)|go:"GO:0097494"(regulation of vesicle size)|rgd:620135|refseq:NP_446289.1|dip:DIP-29761N	-	-	-	figure legend:st1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10116(rat-hippocampus)|taxid:10116(Rattus norvegicus hippocampal neurons)	-	2020/10/30	2020/10/30	rogid:DtE+ZXAZKdCMvUW5K+jXQ5bH07M10116	rogid:AyJEJTqzHtIRWEnMGBzLQP3H5lA10116	rigid:zzsc1zNhBb5nwIRPeFpYOKgC3M8	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q5XIE8	uniprotkb:P52303	intact:EBI-15348306|ensembl:ENSRNOP00000023037	intact:EBI-1040277	psi-mi:itm2b_rat(display_long)|uniprotkb:Itm2b(gene name)|psi-mi:Itm2b(display_short)|uniprotkb:Immature BRI2(gene name synonym)|uniprotkb:Transmembrane protein BRI(gene name synonym)	psi-mi:ap1b1_rat(display_long)|uniprotkb:Ap1b1(gene name)|psi-mi:Ap1b1(display_short)|uniprotkb:Adtb1(gene name synonym)|uniprotkb:Adaptor protein complex AP-1 subunit beta-1(gene name synonym)|uniprotkb:Beta-adaptin 1(gene name synonym)|uniprotkb:Beta-1-adaptin(gene name synonym)|uniprotkb:Golgi adaptor HA1/AP1 adaptin beta subunit(gene name synonym)|uniprotkb:Clathrin assembly protein complex 1 beta large chain(gene name synonym)|uniprotkb:Adaptor-related protein complex 1 subunit beta-1(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Martins et al. (2018)	imex:IM-28469|pubmed:29476059	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26440627|imex:IM-28469-5	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSRNOG00000016271(gene)|ensembl:ENSRNOT00000023037(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001540"(amyloid-beta binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0010008"(endosome membrane)|go:"GO:0030660"(Golgi-associated vesicle membrane)|go:"GO:0031301"(integral component of organelle membrane)|go:"GO:0042985"(negative regulation of amyloid precursor protein biosynthetic process)|interpro:IPR007084(BRICHOS)|interpro:IPR040145|mint:Q5XIE8|refseq:NP_001006964.1|rgd:620727	interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR009028(Clathrin/coatomer adaptor, adaptin-like, appendage, C-terminal subdomain)|interpro:IPR002553(Clathrin/coatomer adaptor, adaptin-like, N-terminal)|interpro:IPR013041(Clathrin/coatomer adaptor, adaptin-like, appendage, Ig-like subdomain)|interpro:IPR008152(Clathrin adaptor, alpha/beta/gamma-adaptin, appendage, Ig-like subdomain)|interpro:IPR013037(Clathrin adaptor, beta-adaptin, appendage, Ig-like subdomain)|interpro:IPR015151(Clathrin adaptor, beta-adaptin, appendage, C-terminal subdomain)|rgd:2064|refseq:NP_058973.1|interpro:IPR016342(Adaptor protein complex, beta subunit)|go:"GO:0001822"(kidney development)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0007368"(determination of left/right symmetry)|go:"GO:0007507"(heart development)|go:"GO:0016192"(vesicle-mediated transport)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030118"(clathrin coat)|go:"GO:0030131"(clathrin adaptor complex)|go:"GO:0030276"(clathrin binding)|go:"GO:0030665"(clathrin-coated vesicle membrane)|go:"GO:0048268"(clathrin coat assembly)|rcsb pdb:1W63|reactome:R-RNO-2132295|reactome:R-RNO-432720|reactome:R-RNO-432722|interpro:IPR026739|interpro:IPR012295(Beta2-adaptin/TATA-box binding, C-terminal)|mint:P52303	-	-	-	figure legend:st1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10116(rat-hippocampus)|taxid:10116(Rattus norvegicus hippocampal neurons)	-	2020/10/30	2020/10/30	rogid:DtE+ZXAZKdCMvUW5K+jXQ5bH07M10116	rogid:oi419FYkBH5Us8n9O9r2j+OvHkM10116	rigid:zzsc1zNhBb5nwIRPeFpYOKgC3M8	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q5XIE8	uniprotkb:P04764	intact:EBI-15348306|ensembl:ENSRNOP00000023037	intact:EBI-915852|uniprotkb:Q66HI3|uniprotkb:Q6AYV3|uniprotkb:Q6P504|ensembl:ENSRNOP00000024106|ensembl:ENSRNOP00000073191	psi-mi:itm2b_rat(display_long)|uniprotkb:Itm2b(gene name)|psi-mi:Itm2b(display_short)|uniprotkb:Immature BRI2(gene name synonym)|uniprotkb:Transmembrane protein BRI(gene name synonym)	psi-mi:enoa_rat(display_long)|uniprotkb:2-phospho-D-glycerate hydro-lyase(gene name synonym)|uniprotkb:Non-neural enolase(gene name synonym)|uniprotkb:Enolase 1(gene name synonym)|uniprotkb:Eno1(gene name)|psi-mi:Eno1(display_short)|uniprotkb:Eno-1(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Martins et al. (2018)	imex:IM-28469|pubmed:29476059	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26440627|imex:IM-28469-5	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSRNOG00000016271(gene)|ensembl:ENSRNOT00000023037(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001540"(amyloid-beta binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0010008"(endosome membrane)|go:"GO:0030660"(Golgi-associated vesicle membrane)|go:"GO:0031301"(integral component of organelle membrane)|go:"GO:0042985"(negative regulation of amyloid precursor protein biosynthetic process)|interpro:IPR007084(BRICHOS)|interpro:IPR040145|mint:Q5XIE8|refseq:NP_001006964.1|rgd:620727	rgd:2553|refseq:NP_001103378.1|refseq:NP_036686.2|ensembl:ENSRNOG00000017895(gene)|ensembl:ENSRNOT00000024106(transcript)|ensembl:ENSRNOT00000081579(transcript)|go:"GO:0000015"(phosphopyruvate hydratase complex)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000287"(magnesium ion binding)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0003723"(RNA binding)|go:"GO:0004634"(phosphopyruvate hydratase activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006096"(glycolytic process)|go:"GO:0009615"(response to virus)|go:"GO:0009986"(cell surface)|go:"GO:0010756"(positive regulation of plasminogen activation)|go:"GO:0016020"(membrane)|go:"GO:0019897"(extrinsic component of plasma membrane)|go:"GO:0019899"(enzyme binding)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0030426"(growth cone)|go:"GO:0031072"(heat shock protein binding)|go:"GO:0032889"(regulation of vacuole fusion, non-autophagic)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043005"(neuron projection)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045121"(membrane raft)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045933"(positive regulation of muscle contraction)|go:"GO:0051020"(GTPase binding)|go:"GO:0051099"(positive regulation of binding)|go:"GO:0061621"(canonical glycolysis)|go:"GO:0070371"(ERK1 and ERK2 cascade)|go:"GO:0071456"(cellular response to hypoxia)|go:"GO:0097060"(synaptic membrane)|go:"GO:0098761"(cellular response to interleukin-7)|go:"GO:0099738"(cell cortex region)|go:"GO:1903298"(negative regulation of hypoxia-induced intrinsic apoptotic signaling pathway)|go:"GO:2001171"(positive regulation of ATP biosynthetic process)|interpro:IPR000941(Enolase)|interpro:IPR020809|interpro:IPR020810|interpro:IPR020811|interpro:IPR029017|interpro:IPR036849|mint:P04764|reactome:R-RNO-70171|reactome:R-RNO-70263	-	-	-	figure legend:st1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10116(rat-hippocampus)|taxid:10116(Rattus norvegicus hippocampal neurons)	-	2020/10/30	2020/10/30	rogid:DtE+ZXAZKdCMvUW5K+jXQ5bH07M10116	rogid:JPjYBxy1gOmhfZso6+adhg5N8UM10116	rigid:zzsc1zNhBb5nwIRPeFpYOKgC3M8	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q5XIE8	uniprotkb:P61751	intact:EBI-15348306|ensembl:ENSRNOP00000023037	intact:EBI-917907|uniprotkb:P36403|ensembl:ENSRNOP00000017692	psi-mi:itm2b_rat(display_long)|uniprotkb:Itm2b(gene name)|psi-mi:Itm2b(display_short)|uniprotkb:Immature BRI2(gene name synonym)|uniprotkb:Transmembrane protein BRI(gene name synonym)	psi-mi:arf4_rat(display_long)|uniprotkb:Arf4(gene name)|psi-mi:Arf4(display_short)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Martins et al. (2018)	imex:IM-28469|pubmed:29476059	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26440627|imex:IM-28469-5	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSRNOG00000016271(gene)|ensembl:ENSRNOT00000023037(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001540"(amyloid-beta binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0010008"(endosome membrane)|go:"GO:0030660"(Golgi-associated vesicle membrane)|go:"GO:0031301"(integral component of organelle membrane)|go:"GO:0042985"(negative regulation of amyloid precursor protein biosynthetic process)|interpro:IPR007084(BRICHOS)|interpro:IPR040145|mint:Q5XIE8|refseq:NP_001006964.1|rgd:620727	rgd:621275|refseq:NP_077065.1|ensembl:ENSRNOG00000012623(gene)|ensembl:ENSRNOT00000017692(transcript)|go:"GO:0003924"(GTPase activity)|go:"GO:0005154"(epidermal growth factor receptor binding)|go:"GO:0005525"(GTP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006471"(protein ADP-ribosylation)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006890"(retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum)|go:"GO:0007173"(epidermal growth factor receptor signaling pathway)|go:"GO:0007420"(brain development)|go:"GO:0007612"(learning)|go:"GO:0016192"(vesicle-mediated transport)|go:"GO:0016477"(cell migration)|go:"GO:0031584"(activation of phospholipase D activity)|go:"GO:0032587"(ruffle membrane)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043197"(dendritic spine)|go:"GO:0045176"(apical protein localization)|go:"GO:0045197"(establishment or maintenance of epithelial cell apical/basal polarity)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048678"(response to axon injury)|go:"GO:0050807"(regulation of synapse organization)|go:"GO:0060996"(dendritic spine development)|go:"GO:0061512"(protein localization to cilium)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099175"(regulation of postsynapse organization)|go:"GO:2000377"(regulation of reactive oxygen species metabolic process)|interpro:IPR005225(Small GTP-binding protein)|interpro:IPR006689(ARF/SAR superfamily)|interpro:IPR027417|mint:P61751|reactome:R-RNO-5620916|reactome:R-RNO-6807878|reactome:R-RNO-6811434	-	-	-	figure legend:st1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10116(rat-hippocampus)|taxid:10116(Rattus norvegicus hippocampal neurons)	-	2020/10/30	2020/10/30	rogid:DtE+ZXAZKdCMvUW5K+jXQ5bH07M10116	rogid:UQ8GuyD6go1ZCYpUU69uTevxoVo10116	rigid:zzsc1zNhBb5nwIRPeFpYOKgC3M8	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q5XIE8	uniprotkb:Q09073	intact:EBI-15348306|ensembl:ENSRNOP00000023037	intact:EBI-918254|ensembl:ENSRNOP00000015913	psi-mi:itm2b_rat(display_long)|uniprotkb:Itm2b(gene name)|psi-mi:Itm2b(display_short)|uniprotkb:Immature BRI2(gene name synonym)|uniprotkb:Transmembrane protein BRI(gene name synonym)	psi-mi:adt2_rat(display_long)|uniprotkb:Slc25a5(gene name)|psi-mi:Slc25a5(display_short)|uniprotkb:Ant2(gene name synonym)|uniprotkb:Adenine nucleotide translocator 2(gene name synonym)|uniprotkb:ADP,ATP carrier protein 2(gene name synonym)|uniprotkb:Solute carrier family 25 member 5(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Martins et al. (2018)	imex:IM-28469|pubmed:29476059	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26440627|imex:IM-28469-5	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSRNOG00000016271(gene)|ensembl:ENSRNOT00000023037(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001540"(amyloid-beta binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0010008"(endosome membrane)|go:"GO:0030660"(Golgi-associated vesicle membrane)|go:"GO:0031301"(integral component of organelle membrane)|go:"GO:0042985"(negative regulation of amyloid precursor protein biosynthetic process)|interpro:IPR007084(BRICHOS)|interpro:IPR040145|mint:Q5XIE8|refseq:NP_001006964.1|rgd:620727	rgd:620353|refseq:NP_476443.1|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005757"(mitochondrial permeability transition pore complex)|go:"GO:0007059"(chromosome segregation)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0015078"(proton transmembrane transporter activity)|go:"GO:0016020"(membrane)|go:"GO:0017077"(oxidative phosphorylation uncoupler activity)|go:"GO:0030183"(B cell differentiation)|go:"GO:0030218"(erythrocyte differentiation)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0042645"(mitochondrial nucleoid)|go:"GO:0045121"(membrane raft)|go:"GO:0046902"(regulation of mitochondrial membrane permeability)|go:"GO:0051503"(adenine nucleotide transport)|go:"GO:0071817"(MMXD complex)|go:"GO:0140021"(mitochondrial ADP transmembrane transport)|go:"GO:1901029"(negative regulation of mitochondrial outer membrane permeabilization involved in apoptotic signaling pathway)|go:"GO:1901526"(positive regulation of mitophagy)|go:"GO:1990544"(mitochondrial ATP transmembrane transport)|go:"GO:1990830"(cellular response to leukemia inhibitory factor)|go:"GO:1990845"(adaptive thermogenesis)|interpro:IPR002067(Mitochondrial carrier protein)|interpro:IPR002113(Adenine nucleotide translocator 1)|interpro:IPR018108|interpro:IPR023395|mint:Q09073|reactome:R-RNO-83936|go:"GO:0005471"("ATP:ADP antiporter activity")|ensembl:ENSRNOG00000039980(gene)|ensembl:ENSRNOT00000015085(transcript)|go:"GO:0000295"(adenine nucleotide transmembrane transporter activity)	-	-	-	figure legend:st1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10116(rat-hippocampus)|taxid:10116(Rattus norvegicus hippocampal neurons)	-	2020/10/30	2020/10/30	rogid:DtE+ZXAZKdCMvUW5K+jXQ5bH07M10116	rogid:WdaA9kTxHaJrlP00OIJCP15jMpI10116	rigid:zzsc1zNhBb5nwIRPeFpYOKgC3M8	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q5XIE8	uniprotkb:Q05962	intact:EBI-15348306|ensembl:ENSRNOP00000023037	intact:EBI-918169	psi-mi:itm2b_rat(display_long)|uniprotkb:Itm2b(gene name)|psi-mi:Itm2b(display_short)|uniprotkb:Immature BRI2(gene name synonym)|uniprotkb:Transmembrane protein BRI(gene name synonym)	psi-mi:adt1_rat(display_long)|uniprotkb:Adenine nucleotide translocator 1(gene name synonym)|uniprotkb:ADP,ATP carrier protein 1(gene name synonym)|uniprotkb:Solute carrier family 25 member 4(gene name synonym)|uniprotkb:Slc25a4(gene name)|psi-mi:Slc25a4(display_short)|uniprotkb:Ant1(gene name synonym)|uniprotkb:Aac1(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Martins et al. (2018)	imex:IM-28469|pubmed:29476059	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26440627|imex:IM-28469-5	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSRNOG00000016271(gene)|ensembl:ENSRNOT00000023037(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001540"(amyloid-beta binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0010008"(endosome membrane)|go:"GO:0030660"(Golgi-associated vesicle membrane)|go:"GO:0031301"(integral component of organelle membrane)|go:"GO:0042985"(negative regulation of amyloid precursor protein biosynthetic process)|interpro:IPR007084(BRICHOS)|interpro:IPR040145|mint:Q5XIE8|refseq:NP_001006964.1|rgd:620727	rgd:620352|refseq:NP_445967.1|interpro:IPR002113(Adenine nucleotide translocator 1)|interpro:IPR002067(Mitochondrial carrier protein)|interpro:IPR018108|interpro:IPR023395|mint:Q05962|go:"GO:0001889"(liver development)|go:"GO:0005471"("ATP:ADP antiporter activity")|go:"GO:0005739"(mitochondrion)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005757"(mitochondrial permeability transition pore complex)|go:"GO:0007507"(heart development)|go:"GO:0007568"(aging)|go:"GO:0008637"(apoptotic mitochondrial changes)|go:"GO:0010667"(negative regulation of cardiac muscle cell apoptotic process)|go:"GO:0015078"(proton transmembrane transporter activity)|go:"GO:0015866"(ADP transport)|go:"GO:0016020"(membrane)|go:"GO:0017077"(oxidative phosphorylation uncoupler activity)|go:"GO:0019899"(enzyme binding)|go:"GO:0032592"(integral component of mitochondrial membrane)|go:"GO:0045121"(membrane raft)|go:"GO:0046902"(regulation of mitochondrial membrane permeability)|go:"GO:0060546"(negative regulation of necroptotic process)|go:"GO:0061051"(positive regulation of cell growth involved in cardiac muscle cell development)|go:"GO:0070555"(response to interleukin-1)|go:"GO:0140021"(mitochondrial ADP transmembrane transport)|go:"GO:1901526"(positive regulation of mitophagy)|go:"GO:1902109"(negative regulation of mitochondrial membrane permeability involved in apoptotic process)|go:"GO:1990544"(mitochondrial ATP transmembrane transport)|go:"GO:1990845"(adaptive thermogenesis)|go:"GO:2000277"(positive regulation of oxidative phosphorylation uncoupler activity)|reactome:R-RNO-83936	-	-	-	figure legend:st1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10116(rat-hippocampus)|taxid:10116(Rattus norvegicus hippocampal neurons)	-	2020/10/30	2020/10/30	rogid:DtE+ZXAZKdCMvUW5K+jXQ5bH07M10116	rogid:NA6aO99oqoOE7rPf9y3s7zKx6HM10116	rigid:zzsc1zNhBb5nwIRPeFpYOKgC3M8	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q5XIE8	uniprotkb:P52481	intact:EBI-15348306|ensembl:ENSRNOP00000023037	intact:EBI-26439519|ensembl:ENSRNOP00000062591|ensembl:ENSRNOP00000074020	psi-mi:itm2b_rat(display_long)|uniprotkb:Itm2b(gene name)|psi-mi:Itm2b(display_short)|uniprotkb:Immature BRI2(gene name synonym)|uniprotkb:Transmembrane protein BRI(gene name synonym)	psi-mi:cap2_rat(display_long)|uniprotkb:Cap2(gene name)|psi-mi:Cap2(display_short)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Martins et al. (2018)	imex:IM-28469|pubmed:29476059	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26440627|imex:IM-28469-5	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSRNOG00000016271(gene)|ensembl:ENSRNOT00000023037(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001540"(amyloid-beta binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0010008"(endosome membrane)|go:"GO:0030660"(Golgi-associated vesicle membrane)|go:"GO:0031301"(integral component of organelle membrane)|go:"GO:0042985"(negative regulation of amyloid precursor protein biosynthetic process)|interpro:IPR007084(BRICHOS)|interpro:IPR040145|mint:Q5XIE8|refseq:NP_001006964.1|rgd:620727	go:"GO:0045761"(regulation of adenylate cyclase activity)|interpro:IPR001837(Adenylate cyclase-associated CAP)|interpro:IPR006599(CARP motif)|interpro:IPR013912(Adenylate cyclase-associated CAP,  C-terminal)|interpro:IPR013992(Adenylate cyclase-associated CAP, N-terminal)|interpro:IPR016098(Cyclase-associated protein CAP/septum formation inhibitor MinC, C-terminal)|interpro:IPR017901|interpro:IPR018106|interpro:IPR028417|interpro:IPR028418|interpro:IPR036222|interpro:IPR036223|mint:P52481|ensembl:ENSRNOG00000043350(gene)|ensembl:ENSRNOT00000065742(transcript)|ensembl:ENSRNOT00000078992(transcript)|go:"GO:0000902"(cell morphogenesis)|go:"GO:0003779"(actin binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0007010"(cytoskeleton organization)|go:"GO:0008179"(adenylate cyclase binding)|go:"GO:0014069"(postsynaptic density)|go:"GO:0019933"(cAMP-mediated signaling)|go:"GO:0030036"(actin cytoskeleton organization)|go:"GO:0042802"(identical protein binding)|refseq:NP_446326.1|refseq:XP_006253815.1|refseq:XP_006253816.1|rgd:620310	-	-	-	figure legend:st1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10116(rat-hippocampus)|taxid:10116(Rattus norvegicus hippocampal neurons)	-	2020/10/30	2020/10/30	rogid:DtE+ZXAZKdCMvUW5K+jXQ5bH07M10116	rogid:V6JzOsegnaJ3Ijkh/+y2oE/9jcU10116	rigid:zzsc1zNhBb5nwIRPeFpYOKgC3M8	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q5XIE8	uniprotkb:P63039	intact:EBI-15348306|ensembl:ENSRNOP00000023037	intact:EBI-432091|uniprotkb:P19226|uniprotkb:P19227|uniprotkb:P97602|ensembl:ENSRNOP00000063666	psi-mi:itm2b_rat(display_long)|uniprotkb:Itm2b(gene name)|psi-mi:Itm2b(display_short)|uniprotkb:Immature BRI2(gene name synonym)|uniprotkb:Transmembrane protein BRI(gene name synonym)	psi-mi:ch60_rat(display_long)|uniprotkb:Heat shock protein 60(gene name synonym)|uniprotkb:60 kDa chaperonin(gene name synonym)|uniprotkb:Chaperonin 60(gene name synonym)|uniprotkb:Mitochondrial matrix protein P1(gene name synonym)|uniprotkb:HSP-65(gene name synonym)|uniprotkb:Hspd1(gene name)|psi-mi:Hspd1(display_short)|uniprotkb:Hsp60(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Martins et al. (2018)	imex:IM-28469|pubmed:29476059	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26440627|imex:IM-28469-5	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSRNOG00000016271(gene)|ensembl:ENSRNOT00000023037(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001540"(amyloid-beta binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0010008"(endosome membrane)|go:"GO:0030660"(Golgi-associated vesicle membrane)|go:"GO:0031301"(integral component of organelle membrane)|go:"GO:0042985"(negative regulation of amyloid precursor protein biosynthetic process)|interpro:IPR007084(BRICHOS)|interpro:IPR040145|mint:Q5XIE8|refseq:NP_001006964.1|rgd:620727	rgd:621314|refseq:NP_071565.2|refseq:XP_006244994.1|go:"GO:0034185"(apolipoprotein binding)|go:"GO:0034186"(apolipoprotein A-I binding)|go:"GO:0034514"(mitochondrial unfolded protein response)|go:"GO:0034605"(cellular response to heat)|go:"GO:0042026"(protein refolding)|go:"GO:0042100"(B cell proliferation)|go:"GO:0042110"(T cell activation)|go:"GO:0042113"(B cell activation)|go:"GO:0042220"(response to cocaine)|go:"GO:0042493"|go:"GO:0042542"(response to hydrogen peroxide)|go:"GO:0042588"(zymogen granule)|go:"GO:0043032"(positive regulation of macrophage activation)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0043627"(response to estrogen)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045041"(protein import into mitochondrial intermembrane space)|go:"GO:0045121"(membrane raft)|go:"GO:0046696"(lipopolysaccharide receptor complex)|go:"GO:0048291"(isotype switching to IgG isotypes)|go:"GO:0050729"(positive regulation of inflammatory response)|go:"GO:0050821"(protein stabilization)|go:"GO:0050870"(positive regulation of T cell activation)|go:"GO:0051087"(chaperone binding)|go:"GO:0051384"(response to glucocorticoid)|go:"GO:0051702"(biological process involved in interaction with symbiont)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071866"(negative regulation of apoptotic process in bone marrow cell)|go:"GO:0097225"(sperm midpiece)|go:"GO:0098761"(cellular response to interleukin-7)|go:"GO:0140030"(modification-dependent protein binding)|go:"GO:1903427"(negative regulation of reactive oxygen species biosynthetic process)|interpro:IPR001844(Chaperonin Cpn60)|interpro:IPR002423(Chaperonin Cpn60/TCP-1)|interpro:IPR018370|interpro:IPR027409|interpro:IPR027410|interpro:IPR027413|mint:P63039|reactome:R-RNO-1268020|ensembl:ENSRNOG00000014525(gene)|ensembl:ENSRNOT00000066589(transcript)|go:"GO:0001530"(lipopolysaccharide binding)|go:"GO:0001666"(response to hypoxia)|go:"GO:0002039"(p53 binding)|go:"GO:0002755"(MyD88-dependent toll-like receptor signaling pathway)|go:"GO:0002842"(positive regulation of T cell mediated immune response to tumor cell)|go:"GO:0002931"(response to ischemia)|go:"GO:0003725"(double-stranded RNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0005769"(early endosome)|go:"GO:0005782"(peroxisomal matrix)|go:"GO:0005791"(rough endoplasmic reticulum)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005905"(clathrin-coated pit)|go:"GO:0006457"(protein folding)|go:"GO:0006458"('de novo' protein folding)|go:"GO:0006919"(activation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0006986"(response to unfolded protein)|go:"GO:0008035"(high-density lipoprotein particle binding)|go:"GO:0008637"(apoptotic mitochondrial changes)|go:"GO:0009408"(response to heat)|go:"GO:0009409"(response to cold)|go:"GO:0009986"(cell surface)|go:"GO:0010033"(response to organic substance)|go:"GO:0014070"(response to organic cyclic compound)|go:"GO:0014823"(response to activity)|go:"GO:0016020"(membrane)|go:"GO:0016853"(isomerase activity)|go:"GO:0019899"(enzyme binding)|go:"GO:0030061"(mitochondrial crista)|go:"GO:0030135"(coated vesicle)|go:"GO:0030141"(secretory granule)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0031985"(Golgi cisterna)|go:"GO:0032496"(response to lipopolysaccharide)|go:"GO:0032727"(positive regulation of interferon-alpha production)|go:"GO:0032729"(positive regulation of interferon-gamma production)|go:"GO:0032733"(positive regulation of interleukin-10 production)|go:"GO:0032735"(positive regulation of interleukin-12 production)|go:"GO:0032755"(positive regulation of interleukin-6 production)|go:"GO:0032760"(positive regulation of tumor necrosis factor production)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033198"(response to ATP)	-	-	-	figure legend:st1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10116(rat-hippocampus)|taxid:10116(Rattus norvegicus hippocampal neurons)	-	2020/10/30	2020/10/30	rogid:DtE+ZXAZKdCMvUW5K+jXQ5bH07M10116	rogid:WD1fQLh4I0ovpakE8KtM1R0XpL410116	rigid:zzsc1zNhBb5nwIRPeFpYOKgC3M8	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q5XIE8	uniprotkb:P61983	intact:EBI-15348306|ensembl:ENSRNOP00000023037	intact:EBI-359821|uniprotkb:A0JPM0|uniprotkb:O70457|uniprotkb:Q9UDP2|uniprotkb:P35214|uniprotkb:Q9UN99|ensembl:ENSRNOP00000001954|ensembl:ENSRNOP00000069671	psi-mi:itm2b_rat(display_long)|uniprotkb:Itm2b(gene name)|psi-mi:Itm2b(display_short)|uniprotkb:Immature BRI2(gene name synonym)|uniprotkb:Transmembrane protein BRI(gene name synonym)	psi-mi:1433g_rat(display_long)|uniprotkb:Ywhag(gene name)|psi-mi:Ywhag(display_short)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Martins et al. (2018)	imex:IM-28469|pubmed:29476059	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26440627|imex:IM-28469-5	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSRNOG00000016271(gene)|ensembl:ENSRNOT00000023037(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001540"(amyloid-beta binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0010008"(endosome membrane)|go:"GO:0030660"(Golgi-associated vesicle membrane)|go:"GO:0031301"(integral component of organelle membrane)|go:"GO:0042985"(negative regulation of amyloid precursor protein biosynthetic process)|interpro:IPR007084(BRICHOS)|interpro:IPR040145|mint:Q5XIE8|refseq:NP_001006964.1|rgd:620727	rgd:62002|refseq:NP_062249.1|ensembl:ENSRNOG00000001436(gene)|ensembl:ENSRNOT00000001954(transcript)|ensembl:ENSRNOT00000084730(transcript)|go:"GO:0003779"(actin binding)|go:"GO:0005080"(protein kinase C binding)|go:"GO:0005159"(insulin-like growth factor receptor binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0006605"(protein targeting)|go:"GO:0007165"(signal transduction)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030234"(enzyme regulator activity)|go:"GO:0030971"(receptor tyrosine kinase binding)|go:"GO:0031982"(vesicle)|go:"GO:0032869"(cellular response to insulin stimulus)|go:"GO:0042802"(identical protein binding)|go:"GO:0045202"(synapse)|go:"GO:0045664"(regulation of neuron differentiation)|go:"GO:0048167"(regulation of synaptic plasticity)|go:"GO:0098793"(presynapse)|interpro:IPR000308(14-3-3 protein)|interpro:IPR023409|interpro:IPR023410|interpro:IPR036815|mint:P61983|reactome:R-RNO-111447|reactome:R-RNO-2565942|reactome:R-RNO-380259|reactome:R-RNO-380270|reactome:R-RNO-380284|reactome:R-RNO-380320|reactome:R-RNO-5620912|reactome:R-RNO-5625740|reactome:R-RNO-5628897|reactome:R-RNO-75035|reactome:R-RNO-8854518|reactome:R-RNO-9614399|refseq:XP_006249246.2	-	-	-	figure legend:st1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10116(rat-hippocampus)|taxid:10116(Rattus norvegicus hippocampal neurons)	-	2020/10/30	2020/10/30	rogid:DtE+ZXAZKdCMvUW5K+jXQ5bH07M10116	rogid:u1cd71h0RPgTOEMrQVhOelsxWnM10116	rigid:zzsc1zNhBb5nwIRPeFpYOKgC3M8	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q5XIE8	uniprotkb:P12075	intact:EBI-15348306|ensembl:ENSRNOP00000023037	intact:EBI-26439500|ensembl:ENSRNOP00000022487	psi-mi:itm2b_rat(display_long)|uniprotkb:Itm2b(gene name)|psi-mi:Itm2b(display_short)|uniprotkb:Immature BRI2(gene name synonym)|uniprotkb:Transmembrane protein BRI(gene name synonym)	psi-mi:cox5b_rat(display_long)|uniprotkb:Cox5b(gene name)|psi-mi:Cox5b(display_short)|uniprotkb:Cytochrome c oxidase polypeptide Vb(gene name synonym)|uniprotkb:Cytochrome c oxidase subunit VIA*(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Martins et al. (2018)	imex:IM-28469|pubmed:29476059	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26440627|imex:IM-28469-5	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSRNOG00000016271(gene)|ensembl:ENSRNOT00000023037(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001540"(amyloid-beta binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0010008"(endosome membrane)|go:"GO:0030660"(Golgi-associated vesicle membrane)|go:"GO:0031301"(integral component of organelle membrane)|go:"GO:0042985"(negative regulation of amyloid precursor protein biosynthetic process)|interpro:IPR007084(BRICHOS)|interpro:IPR040145|mint:Q5XIE8|refseq:NP_001006964.1|rgd:620727	ensembl:ENSRNOG00000016660(gene)|ensembl:ENSRNOT00000022487(transcript)|go:"GO:0004129"(cytochrome-c oxidase activity)|go:"GO:0005739"(mitochondrion)|go:"GO:0005751"(mitochondrial respiratory chain complex IV)|go:"GO:0006123"(mitochondrial electron transport, cytochrome c to oxygen)|go:"GO:0009725"(response to hormone)|go:"GO:0043434"(response to peptide hormone)|go:"GO:0046872"(metal ion binding)|interpro:IPR002124(Cytochrome c oxidase, subunit Vb)|interpro:IPR020893|interpro:IPR036972|mint:P12075|reactome:R-RNO-5628897|reactome:R-RNO-611105|reactome:R-RNO-9707564|refseq:NP_446038.1|rgd:620608	-	-	-	figure legend:st1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10116(rat-hippocampus)|taxid:10116(Rattus norvegicus hippocampal neurons)	-	2020/10/30	2020/10/30	rogid:DtE+ZXAZKdCMvUW5K+jXQ5bH07M10116	rogid:6sI637xqMkBCynZU8PXYj77PfKQ10116	rigid:zzsc1zNhBb5nwIRPeFpYOKgC3M8	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q5XIE8	uniprotkb:P63081	intact:EBI-15348306|ensembl:ENSRNOP00000023037	intact:EBI-2025009|uniprotkb:P23967|ensembl:ENSRNOP00000008736	psi-mi:itm2b_rat(display_long)|uniprotkb:Itm2b(gene name)|psi-mi:Itm2b(display_short)|uniprotkb:Immature BRI2(gene name synonym)|uniprotkb:Transmembrane protein BRI(gene name synonym)	psi-mi:vatl_rat(display_long)|uniprotkb:Atp6v0c(gene name)|psi-mi:Atp6v0c(display_short)|uniprotkb:Atp6c(gene name synonym)|uniprotkb:Atp6l(gene name synonym)|uniprotkb:Atpl(gene name synonym)|uniprotkb:Vacuolar proton pump 16 kDa proteolipid subunit(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Martins et al. (2018)	imex:IM-28469|pubmed:29476059	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26440627|imex:IM-28469-5	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSRNOG00000016271(gene)|ensembl:ENSRNOT00000023037(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001540"(amyloid-beta binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0010008"(endosome membrane)|go:"GO:0030660"(Golgi-associated vesicle membrane)|go:"GO:0031301"(integral component of organelle membrane)|go:"GO:0042985"(negative regulation of amyloid precursor protein biosynthetic process)|interpro:IPR007084(BRICHOS)|interpro:IPR040145|mint:Q5XIE8|refseq:NP_001006964.1|rgd:620727	rgd:621394|refseq:NP_570836.1|refseq:XP_006245960.1|ensembl:ENSRNOG00000006542(gene)|ensembl:ENSRNOT00000008736(transcript)|go:"GO:0005764"(lysosome)|go:"GO:0005774"(vacuolar membrane)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030177"(positive regulation of Wnt signaling pathway)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0033179"(proton-transporting V-type ATPase, V0 domain)|go:"GO:0046961"(proton-transporting ATPase activity, rotational mechanism)|go:"GO:0070374"(positive regulation of ERK1 and ERK2 cascade)|go:"GO:1904093"(negative regulation of autophagic cell death)|interpro:IPR000245(ATPase, V0 complex, proteolipid subunit C,)|interpro:IPR002379(ATPase, F0/V0 complex, subunit C)|interpro:IPR011555(ATPase, V0 complex, proteolipid subunit C, eukaryotic)|interpro:IPR035921|mint:P63081|rcsb pdb:6VQ6|rcsb pdb:6VQ7|rcsb pdb:6VQ8|rcsb pdb:6VQC|rcsb pdb:6VQG|rcsb pdb:6VQH|reactome:R-RNO-1222556|reactome:R-RNO-6798695|reactome:R-RNO-77387|reactome:R-RNO-917977|reactome:R-RNO-9639288|reactome:R-RNO-983712	-	-	-	figure legend:st1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10116(rat-hippocampus)|taxid:10116(Rattus norvegicus hippocampal neurons)	-	2020/10/30	2020/10/30	rogid:DtE+ZXAZKdCMvUW5K+jXQ5bH07M10116	rogid:Qx4BtXXIXdTlTTWE3nBHM8kThHU10116	rigid:zzsc1zNhBb5nwIRPeFpYOKgC3M8	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q5XIE8	uniprotkb:P25286	intact:EBI-15348306|ensembl:ENSRNOP00000023037	intact:EBI-2024887|intact:EBI-11702593	psi-mi:itm2b_rat(display_long)|uniprotkb:Itm2b(gene name)|psi-mi:Itm2b(display_short)|uniprotkb:Immature BRI2(gene name synonym)|uniprotkb:Transmembrane protein BRI(gene name synonym)	psi-mi:vpp1_rat(display_long)|uniprotkb:Atp6v0a1(gene name)|psi-mi:Atp6v0a1(display_short)|uniprotkb:Atp6n1(gene name synonym)|uniprotkb:Vpp1(gene name synonym)|uniprotkb:Vacuolar proton translocating ATPase 116 kDa subunit a isoform 1(gene name synonym)|uniprotkb:Clathrin-coated vesicle/synaptic vesicle proton pump 116 kDa subunit(gene name synonym)|uniprotkb:Vacuolar proton pump subunit 1(gene name synonym)|uniprotkb:Vacuolar adenosine triphosphatase subunit Ac116(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Martins et al. (2018)	imex:IM-28469|pubmed:29476059	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26440627|imex:IM-28469-5	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSRNOG00000016271(gene)|ensembl:ENSRNOT00000023037(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001540"(amyloid-beta binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0010008"(endosome membrane)|go:"GO:0030660"(Golgi-associated vesicle membrane)|go:"GO:0031301"(integral component of organelle membrane)|go:"GO:0042985"(negative regulation of amyloid precursor protein biosynthetic process)|interpro:IPR007084(BRICHOS)|interpro:IPR040145|mint:Q5XIE8|refseq:NP_001006964.1|rgd:620727	interpro:IPR026028|interpro:IPR002490(ATPase, V0/A0 complex, 116-kDa subunit)|rgd:68405|refseq:NP_113792.2|mint:P25286|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0007035"(vacuolar acidification)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0016241"(regulation of macroautophagy)|go:"GO:0016471"(vacuolar proton-transporting V-type ATPase complex)|go:"GO:0030285"(integral component of synaptic vesicle membrane)|go:"GO:0042470"(melanosome)|go:"GO:0043195"(terminal bouton)|go:"GO:0043229"(intracellular organelle)|go:"GO:0046961"(proton-transporting ATPase activity, rotational mechanism)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051117"(ATPase binding)|go:"GO:1901998"(toxin transport)|rcsb pdb:6VQ6|rcsb pdb:6VQ7|rcsb pdb:6VQ8|rcsb pdb:6VQC|rcsb pdb:6VQG|rcsb pdb:6VQH|rcsb pdb:6VQI|rcsb pdb:6VQJ|rcsb pdb:6VQK|reactome:R-RNO-1222556|reactome:R-RNO-6798695|reactome:R-RNO-77387|reactome:R-RNO-917977|reactome:R-RNO-983712|go:"GO:0000220"(vacuolar proton-transporting V-type ATPase, V0 domain)	-	-	-	figure legend:st1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10116(rat-hippocampus)|taxid:10116(Rattus norvegicus hippocampal neurons)	-	2020/10/30	2020/10/30	rogid:DtE+ZXAZKdCMvUW5K+jXQ5bH07M10116	rogid:M+mzcb5KThafTTcJpimDmH5I4fk10116	rigid:zzsc1zNhBb5nwIRPeFpYOKgC3M8	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q5XIE8	uniprotkb:Q9R1Z0	intact:EBI-15348306|ensembl:ENSRNOP00000023037	intact:EBI-2255834|uniprotkb:Q6GSZ1|uniprotkb:Q9ESR2|uniprotkb:Q9JI31|uniprotkb:Q9WTU2	psi-mi:itm2b_rat(display_long)|uniprotkb:Itm2b(gene name)|psi-mi:Itm2b(display_short)|uniprotkb:Immature BRI2(gene name synonym)|uniprotkb:Transmembrane protein BRI(gene name synonym)	psi-mi:vdac3_rat(display_long)|uniprotkb:Vdac3(gene name)|psi-mi:Vdac3(display_short)|uniprotkb:Outer mitochondrial membrane protein porin 3(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Martins et al. (2018)	imex:IM-28469|pubmed:29476059	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26440627|imex:IM-28469-5	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSRNOG00000016271(gene)|ensembl:ENSRNOT00000023037(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001540"(amyloid-beta binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0010008"(endosome membrane)|go:"GO:0030660"(Golgi-associated vesicle membrane)|go:"GO:0031301"(integral component of organelle membrane)|go:"GO:0042985"(negative regulation of amyloid precursor protein biosynthetic process)|interpro:IPR007084(BRICHOS)|interpro:IPR040145|mint:Q5XIE8|refseq:NP_001006964.1|rgd:620727	rgd:621577|refseq:NP_112645.1|interpro:IPR001925(Porin, eukaryotic type)|interpro:IPR030271|interpro:IPR027246|mint:Q9R1Z0|interpro:IPR023614|go:"GO:0000166"(nucleotide binding)|go:"GO:0001662"(behavioral fear response)|go:"GO:0005739"(mitochondrion)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005791"(rough endoplasmic reticulum)|go:"GO:0007268"(chemical synaptic transmission)|go:"GO:0007270"(neuron-neuron synaptic transmission)|go:"GO:0007612"(learning)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0008308"(voltage-gated anion channel activity)|go:"GO:0015288"(porin activity)|go:"GO:0016020"(membrane)|go:"GO:0046930"(pore complex)|go:"GO:1902017"(regulation of cilium assembly)|reactome:R-RNO-5689880	-	-	-	figure legend:st1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10116(rat-hippocampus)|taxid:10116(Rattus norvegicus hippocampal neurons)	-	2020/10/30	2020/10/30	rogid:DtE+ZXAZKdCMvUW5K+jXQ5bH07M10116	rogid:32zwKuZVCTarCx4d4bMt6Apc6cE10116	rigid:zzsc1zNhBb5nwIRPeFpYOKgC3M8	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q5XIE8	uniprotkb:Q9JJW3	intact:EBI-15348306|ensembl:ENSRNOP00000023037	intact:EBI-26437382|ensembl:ENSRNOP00000027496|ensembl:ENSRNOP00000061817	psi-mi:itm2b_rat(display_long)|uniprotkb:Itm2b(gene name)|psi-mi:Itm2b(display_short)|uniprotkb:Immature BRI2(gene name synonym)|uniprotkb:Transmembrane protein BRI(gene name synonym)	psi-mi:atpmk_rat(display_long)|uniprotkb:Atp5mk(gene name)|psi-mi:Atp5mk(display_short)|uniprotkb:ATP synthase membrane subunit DAPIT, mitochondrial(gene name synonym)|uniprotkb:Atp5md(gene name synonym)|uniprotkb:Dapit(gene name synonym)|uniprotkb:Diabetes-associated protein in insulin-sensitive tissues(gene name synonym)|uniprotkb:Up-regulated during skeletal muscle growth protein 5(gene name synonym)|uniprotkb:Usmg5(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Martins et al. (2018)	imex:IM-28469|pubmed:29476059	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26440627|imex:IM-28469-5	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSRNOG00000016271(gene)|ensembl:ENSRNOT00000023037(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001540"(amyloid-beta binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0010008"(endosome membrane)|go:"GO:0030660"(Golgi-associated vesicle membrane)|go:"GO:0031301"(integral component of organelle membrane)|go:"GO:0042985"(negative regulation of amyloid precursor protein biosynthetic process)|interpro:IPR007084(BRICHOS)|interpro:IPR040145|mint:Q5XIE8|refseq:NP_001006964.1|rgd:620727	ensembl:ENSRNOG00000020296(gene)|ensembl:ENSRNOG00000042869(gene)|ensembl:ENSRNOT00000027496(transcript)|ensembl:ENSRNOT00000064931(transcript)|go:"GO:0005739"(mitochondrion)|go:"GO:0005753"(mitochondrial proton-transporting ATP synthase complex)|go:"GO:0016021"(integral component of membrane)|interpro:IPR009125(DAPIT)|mint:Q9JJW3|refseq:NP_598228.1|refseq:XP_008766441.1|refseq:XP_008773622.1|rgd:631426	-	-	-	figure legend:st1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10116(rat-hippocampus)|taxid:10116(Rattus norvegicus hippocampal neurons)	-	2020/10/30	2020/10/30	rogid:DtE+ZXAZKdCMvUW5K+jXQ5bH07M10116	rogid:PeUvTdLYLEDd4wXYTYtUyyslllY10116	rigid:zzsc1zNhBb5nwIRPeFpYOKgC3M8	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q5XIE8	uniprotkb:P11167	intact:EBI-15348306|ensembl:ENSRNOP00000023037	intact:EBI-960654|ensembl:ENSRNOP00000061340	psi-mi:itm2b_rat(display_long)|uniprotkb:Itm2b(gene name)|psi-mi:Itm2b(display_short)|uniprotkb:Immature BRI2(gene name synonym)|uniprotkb:Transmembrane protein BRI(gene name synonym)	psi-mi:gtr1_rat(display_long)|uniprotkb:Slc2a1(gene name)|psi-mi:Slc2a1(display_short)|uniprotkb:Glut1(gene name synonym)|uniprotkb:Glucose transporter type 1, erythrocyte/brain(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Martins et al. (2018)	imex:IM-28469|pubmed:29476059	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26440627|imex:IM-28469-5	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSRNOG00000016271(gene)|ensembl:ENSRNOT00000023037(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001540"(amyloid-beta binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0010008"(endosome membrane)|go:"GO:0030660"(Golgi-associated vesicle membrane)|go:"GO:0031301"(integral component of organelle membrane)|go:"GO:0042985"(negative regulation of amyloid precursor protein biosynthetic process)|interpro:IPR007084(BRICHOS)|interpro:IPR040145|mint:Q5XIE8|refseq:NP_001006964.1|rgd:620727	ensembl:ENSRNOG00000007284(gene)|ensembl:ENSRNOT00000064452(transcript)|go:"GO:0001666"(response to hypoxia)|go:"GO:0001917"(photoreceptor inner segment)|go:"GO:0001939"(female pronucleus)|go:"GO:0005324"(long-chain fatty acid transporter activity)|go:"GO:0005355"(glucose transmembrane transporter activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0005901"(caveola)|go:"GO:0005911"(cell-cell junction)|go:"GO:0006970"(response to osmotic stress)|go:"GO:0007417"(central nervous system development)|go:"GO:0007565"(female pregnancy)|go:"GO:0014704"(intercalated disc)|go:"GO:0015911"(long-chain fatty acid import across plasma membrane)|go:"GO:0016020"(membrane)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0019900"(kinase binding)|go:"GO:0021987"(cerebral cortex development)|go:"GO:0030018"(Z disc)|go:"GO:0030496"(midbody)|go:"GO:0030864"(cortical actin cytoskeleton)|go:"GO:0032868"(response to insulin)|go:"GO:0033300"(dehydroascorbic acid transmembrane transporter activity)|go:"GO:0042149"(cellular response to glucose starvation)|go:"GO:0042383"(sarcolemma)|go:"GO:0042802"(identical protein binding)|go:"GO:0042908"(xenobiotic transport)|go:"GO:0042910"(xenobiotic transmembrane transporter activity)|go:"GO:0043621"(protein self-association)|go:"GO:0045121"(membrane raft)|go:"GO:0031982"(vesicle)|go:"GO:0045202"(synapse)|go:"GO:0045494"(photoreceptor cell maintenance)|go:"GO:0055056"(D-glucose transmembrane transporter activity)|go:"GO:0065003"(protein-containing complex assembly)|go:"GO:0070837"(dehydroascorbic acid transport)|go:"GO:0071260"(cellular response to mechanical stimulus)|go:"GO:0071474"(cellular hyperosmotic response)|go:"GO:0098708"(glucose import across plasma membrane)|go:"GO:0098793"(presynapse)|go:"GO:0150104"(transport across blood-brain barrier)|go:"GO:1904016"(response to Thyroglobulin triiodothyronine)|go:"GO:1904659"(glucose transmembrane transport)|interpro:IPR002439("Glucose transporter, type 1 (GLUT1)")|interpro:IPR003663(Sugar transporter)|interpro:IPR005828(General substrate transporter)|interpro:IPR005829(Sugar transporter, conserved site)|interpro:IPR020846|interpro:IPR036259|mint:P11167|reactome:R-RNO-189200|reactome:R-RNO-422356|reactome:R-RNO-5653890|reactome:R-RNO-196836|rgd:3704|refseq:NP_620182.1	-	-	-	figure legend:st1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10116(rat-hippocampus)|taxid:10116(Rattus norvegicus hippocampal neurons)	-	2020/10/30	2020/10/30	rogid:DtE+ZXAZKdCMvUW5K+jXQ5bH07M10116	rogid:JriqkyQOrkEOA8WptfkF8G5sD2w10116	rigid:zzsc1zNhBb5nwIRPeFpYOKgC3M8	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q5XIE8	uniprotkb:P13638	intact:EBI-15348306|ensembl:ENSRNOP00000023037	intact:EBI-26437335	psi-mi:itm2b_rat(display_long)|uniprotkb:Itm2b(gene name)|psi-mi:Itm2b(display_short)|uniprotkb:Immature BRI2(gene name synonym)|uniprotkb:Transmembrane protein BRI(gene name synonym)	psi-mi:at1b2_rat(display_long)|uniprotkb:Atp1b2(gene name)|psi-mi:Atp1b2(display_short)|uniprotkb:Sodium/potassium-dependent ATPase subunit beta-2(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Martins et al. (2018)	imex:IM-28469|pubmed:29476059	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26440627|imex:IM-28469-5	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSRNOG00000016271(gene)|ensembl:ENSRNOT00000023037(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001540"(amyloid-beta binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0010008"(endosome membrane)|go:"GO:0030660"(Golgi-associated vesicle membrane)|go:"GO:0031301"(integral component of organelle membrane)|go:"GO:0042985"(negative regulation of amyloid precursor protein biosynthetic process)|interpro:IPR007084(BRICHOS)|interpro:IPR040145|mint:Q5XIE8|refseq:NP_001006964.1|rgd:620727	go:"GO:0120036"(plasma membrane bounded cell projection organization)|go:"GO:1901018"(positive regulation of potassium ion transmembrane transporter activity)|go:"GO:1903278"(positive regulation of sodium ion export across plasma membrane)|go:"GO:1903288"(positive regulation of potassium ion import across plasma membrane)|go:"GO:1903976"(negative regulation of glial cell migration)|go:"GO:1990573"(potassium ion import across plasma membrane)|reactome:R-RNO-210991|reactome:R-RNO-5578775|reactome:R-RNO-936837|go:"GO:0098984"(neuron to neuron synapse)|go:"GO:0001671"(ATPase activator activity)|go:"GO:0001895"(retina homeostasis)|go:"GO:0001917"(photoreceptor inner segment)|go:"GO:0005391"("P-type sodium:potassium-exchanging transporter activity")|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0005890"("sodium:potassium-exchanging ATPase complex")|go:"GO:0006883"(cellular sodium ion homeostasis)|go:"GO:0009897"(external side of plasma membrane)|go:"GO:0010976"(positive regulation of neuron projection development)|go:"GO:0016020"(membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0016328"(lateral plasma membrane)|go:"GO:0021670"(lateral ventricle development)|go:"GO:0021678"(third ventricle development)|go:"GO:0021944"(neuronal-glial interaction involved in hindbrain glial-mediated radial cell migration)|go:"GO:0030007"(cellular potassium ion homeostasis)|go:"GO:0030674"(protein-macromolecule adaptor activity)|go:"GO:0031253"(cell projection membrane)|go:"GO:0031589"(cell-substrate adhesion)|go:"GO:0032781"(positive regulation of ATP-dependent activity)|go:"GO:0036376"(sodium ion export across plasma membrane)|go:"GO:0044298"(cell body membrane)|go:"GO:0045494"(photoreceptor cell maintenance)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0050821"(protein stabilization)|go:"GO:0051117"(ATPase binding)|go:"GO:0061744"(motor behavior)|go:"GO:0071944"(cell periphery)|go:"GO:0086009"(membrane repolarization)|go:"GO:0097449"(astrocyte projection)|go:"GO:0097450"(astrocyte end-foot)|mint:P13638|interpro:IPR000402(ATPase, P-type cation exchange, beta subunit)|interpro:IPR038702|rgd:2171	-	-	-	figure legend:st1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10116(rat-hippocampus)|taxid:10116(Rattus norvegicus hippocampal neurons)	-	2020/10/30	2020/10/30	rogid:DtE+ZXAZKdCMvUW5K+jXQ5bH07M10116	rogid:bl1sa8rfoB1To7Q5na/Mx5QU8Mw10116	rigid:zzsc1zNhBb5nwIRPeFpYOKgC3M8	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q5XIE8	uniprotkb:P07340	intact:EBI-15348306|ensembl:ENSRNOP00000023037	intact:EBI-2640714|uniprotkb:Q63062|ensembl:ENSRNOP00000003932	psi-mi:itm2b_rat(display_long)|uniprotkb:Itm2b(gene name)|psi-mi:Itm2b(display_short)|uniprotkb:Immature BRI2(gene name synonym)|uniprotkb:Transmembrane protein BRI(gene name synonym)	psi-mi:at1b1_rat(display_long)|uniprotkb:Atp1b1(gene name)|psi-mi:Atp1b1(display_short)|uniprotkb:Sodium/potassium-dependent ATPase subunit beta-1(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Martins et al. (2018)	imex:IM-28469|pubmed:29476059	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26440627|imex:IM-28469-5	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSRNOG00000016271(gene)|ensembl:ENSRNOT00000023037(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001540"(amyloid-beta binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0010008"(endosome membrane)|go:"GO:0030660"(Golgi-associated vesicle membrane)|go:"GO:0031301"(integral component of organelle membrane)|go:"GO:0042985"(negative regulation of amyloid precursor protein biosynthetic process)|interpro:IPR007084(BRICHOS)|interpro:IPR040145|mint:Q5XIE8|refseq:NP_001006964.1|rgd:620727	rgd:2170|refseq:NP_037245.2|ensembl:ENSRNOG00000002934(gene)|ensembl:ENSRNOT00000003932(transcript)|go:"GO:0001666"(response to hypoxia)|go:"GO:0001671"(ATPase activator activity)|go:"GO:0001824"(blastocyst development)|go:"GO:0005391"("P-type sodium:potassium-exchanging transporter activity")|go:"GO:0005886"(plasma membrane)|go:"GO:0005890"("sodium:potassium-exchanging ATPase complex")|go:"GO:0005901"(caveola)|go:"GO:0006813"(potassium ion transport)|go:"GO:0006814"(sodium ion transport)|go:"GO:0006874"(cellular calcium ion homeostasis)|go:"GO:0006883"(cellular sodium ion homeostasis)|go:"GO:0007155"(cell adhesion)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0010882"(regulation of cardiac muscle contraction by calcium ion signaling)|go:"GO:0050821"(protein stabilization)|go:"GO:0051117"(ATPase binding)|go:"GO:0055119"(relaxation of cardiac muscle)|go:"GO:0060048"(cardiac muscle contraction)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0086009"(membrane repolarization)|go:"GO:0098655"(cation transmembrane transport)|go:"GO:1901018"(positive regulation of potassium ion transmembrane transporter activity)|go:"GO:1903169"(regulation of calcium ion transmembrane transport)|go:"GO:0014704"(intercalated disc)|go:"GO:0016020"(membrane)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0016328"(lateral plasma membrane)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030001"(metal ion transport)|go:"GO:1903278"(positive regulation of sodium ion export across plasma membrane)|go:"GO:0030007"(cellular potassium ion homeostasis)|go:"GO:1903281"("positive regulation of calcium:sodium antiporter activity")|go:"GO:1903288"(positive regulation of potassium ion import across plasma membrane)|go:"GO:0030315"(T-tubule)|go:"GO:1903408"("positive regulation of P-type sodium:potassium-exchanging transporter activity")|go:"GO:0030674"(protein-macromolecule adaptor activity)|go:"GO:0031090"(organelle membrane)|go:"GO:0032781"(positive regulation of ATP-dependent activity)|go:"GO:0035725"(sodium ion transmembrane transport)|go:"GO:0036126"(sperm flagellum)|go:"GO:0036376"(sodium ion export across plasma membrane)|go:"GO:0042383"(sarcolemma)|go:"GO:0046034"(ATP metabolic process)|go:"GO:0046982"(protein heterodimerization activity)|interpro:IPR000402(ATPase, P-type cation exchange, beta subunit)|interpro:IPR015565(Sodium/Potassium-Dependent ATPase Beta-1 Subunit)|interpro:IPR038702|mint:P07340|reactome:R-RNO-210991|reactome:R-RNO-5578775|reactome:R-RNO-936837|go:"GO:1990573"(potassium ion import across plasma membrane)	-	-	-	figure legend:st1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10116(rat-hippocampus)|taxid:10116(Rattus norvegicus hippocampal neurons)	-	2020/10/30	2020/10/30	rogid:DtE+ZXAZKdCMvUW5K+jXQ5bH07M10116	rogid:gJJ7PU6Tz3znT4wWy7GIPSV/x9w10116	rigid:zzsc1zNhBb5nwIRPeFpYOKgC3M8	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q5XIE8	uniprotkb:P49432	intact:EBI-15348306|ensembl:ENSRNOP00000023037	intact:EBI-917663|uniprotkb:Q6AY95|ensembl:ENSRNOP00000010545	psi-mi:itm2b_rat(display_long)|uniprotkb:Itm2b(gene name)|psi-mi:Itm2b(display_short)|uniprotkb:Immature BRI2(gene name synonym)|uniprotkb:Transmembrane protein BRI(gene name synonym)	psi-mi:odpb_rat(display_long)|uniprotkb:Pdhb(gene name)|psi-mi:Pdhb(display_short)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Martins et al. (2018)	imex:IM-28469|pubmed:29476059	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26440627|imex:IM-28469-5	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSRNOG00000016271(gene)|ensembl:ENSRNOT00000023037(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001540"(amyloid-beta binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0010008"(endosome membrane)|go:"GO:0030660"(Golgi-associated vesicle membrane)|go:"GO:0031301"(integral component of organelle membrane)|go:"GO:0042985"(negative regulation of amyloid precursor protein biosynthetic process)|interpro:IPR007084(BRICHOS)|interpro:IPR040145|mint:Q5XIE8|refseq:NP_001006964.1|rgd:620727	rgd:1359146|refseq:NP_001007621.1|ensembl:ENSRNOG00000007895(gene)|ensembl:ENSRNOT00000010545(transcript)|go:"GO:0004739"("pyruvate dehydrogenase (acetyl-transferring) activity")|go:"GO:0005739"(mitochondrion)|go:"GO:0005967"(mitochondrial pyruvate dehydrogenase complex)|go:"GO:0006006"(glucose metabolic process)|go:"GO:0006086"(acetyl-CoA biosynthetic process from pyruvate)|go:"GO:0006099"(tricarboxylic acid cycle)|go:"GO:0045254"(pyruvate dehydrogenase complex)|interpro:IPR005475(Transketolase, central region)|interpro:IPR009014(Transketolase, C-terminal/Pyruvate-ferredoxin oxidoreductase, domain II)|interpro:IPR027110|interpro:IPR029061|interpro:IPR033248|mint:P49432|reactome:R-RNO-204174|reactome:R-RNO-389661|reactome:R-RNO-5362517|reactome:R-RNO-70268|refseq:XP_006251816.1	-	-	-	figure legend:st1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10116(rat-hippocampus)|taxid:10116(Rattus norvegicus hippocampal neurons)	-	2020/10/30	2020/10/30	rogid:DtE+ZXAZKdCMvUW5K+jXQ5bH07M10116	rogid:IauZD1wmQ+/x/0WJZxx7kyX8FT410116	rigid:zzsc1zNhBb5nwIRPeFpYOKgC3M8	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q5XIE8	uniprotkb:Q66HF1	intact:EBI-15348306|ensembl:ENSRNOP00000023037	intact:EBI-21997221|ensembl:ENSRNOP00000015851	psi-mi:itm2b_rat(display_long)|uniprotkb:Itm2b(gene name)|psi-mi:Itm2b(display_short)|uniprotkb:Immature BRI2(gene name synonym)|uniprotkb:Transmembrane protein BRI(gene name synonym)	psi-mi:ndus1_rat(display_long)|uniprotkb:Ndufs1(gene name)|psi-mi:Ndufs1(display_short)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Martins et al. (2018)	imex:IM-28469|pubmed:29476059	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26440627|imex:IM-28469-5	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSRNOG00000016271(gene)|ensembl:ENSRNOT00000023037(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001540"(amyloid-beta binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0010008"(endosome membrane)|go:"GO:0030660"(Golgi-associated vesicle membrane)|go:"GO:0031301"(integral component of organelle membrane)|go:"GO:0042985"(negative regulation of amyloid precursor protein biosynthetic process)|interpro:IPR007084(BRICHOS)|interpro:IPR040145|mint:Q5XIE8|refseq:NP_001006964.1|rgd:620727	rgd:1359670|refseq:NP_001005550.1|ensembl:ENSRNOG00000011849(gene)|ensembl:ENSRNOT00000015852(transcript)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005747"(mitochondrial respiratory chain complex I)|go:"GO:0005758"(mitochondrial intermembrane space)|go:"GO:0006120"(mitochondrial electron transport, NADH to ubiquinone)|go:"GO:0008137"("NADH dehydrogenase (ubiquinone) activity")|go:"GO:0008637"(apoptotic mitochondrial changes)|go:"GO:0009055"(electron transfer activity)|go:"GO:0032981"(mitochondrial respiratory chain complex I assembly)|go:"GO:0045333"(cellular respiration)|go:"GO:0046034"(ATP metabolic process)|go:"GO:0046872"(metal ion binding)|go:"GO:0051537"(2 iron, 2 sulfur cluster binding)|go:"GO:0051539"(4 iron, 4 sulfur cluster binding)|go:"GO:0051881"(regulation of mitochondrial membrane potential)|go:"GO:0072593"(reactive oxygen species metabolic process)|interpro:IPR000283(NADH dehydrogenase 75 kDa subunit, conserved site)|interpro:IPR001041(Ferredoxin)|interpro:IPR006656(Molybdopterin oxidoreductase)|interpro:IPR006963(Molybdopterin oxidoreductase Fe4S4 region)|interpro:IPR010228(NADH-quinone oxidoreductase, chain G)|interpro:IPR015405(NADH-quinone oxidoreductase, chain G, C-terminal)|interpro:IPR019574|interpro:IPR036010|mint:Q66HF1|reactome:R-RNO-611105|reactome:R-RNO-6799198	-	-	-	figure legend:st1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10116(rat-hippocampus)|taxid:10116(Rattus norvegicus hippocampal neurons)	-	2020/10/30	2020/10/30	rogid:DtE+ZXAZKdCMvUW5K+jXQ5bH07M10116	rogid:rBq5pYwfc7co6OKLTc8OUF4jX1g10116	rigid:zzsc1zNhBb5nwIRPeFpYOKgC3M8	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q5XIE8	uniprotkb:P97700	intact:EBI-15348306|ensembl:ENSRNOP00000023037	intact:EBI-918109	psi-mi:itm2b_rat(display_long)|uniprotkb:Itm2b(gene name)|psi-mi:Itm2b(display_short)|uniprotkb:Immature BRI2(gene name synonym)|uniprotkb:Transmembrane protein BRI(gene name synonym)	psi-mi:m2om_rat(display_long)|uniprotkb:Solute carrier family 25 member 11(gene name synonym)|uniprotkb:Slc25a11(gene name)|psi-mi:Slc25a11(display_short)|uniprotkb:Slc20a4(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Martins et al. (2018)	imex:IM-28469|pubmed:29476059	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26440627|imex:IM-28469-5	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSRNOG00000016271(gene)|ensembl:ENSRNOT00000023037(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001540"(amyloid-beta binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0010008"(endosome membrane)|go:"GO:0030660"(Golgi-associated vesicle membrane)|go:"GO:0031301"(integral component of organelle membrane)|go:"GO:0042985"(negative regulation of amyloid precursor protein biosynthetic process)|interpro:IPR007084(BRICHOS)|interpro:IPR040145|mint:Q5XIE8|refseq:NP_001006964.1|rgd:620727	rgd:708476|refseq:NP_071793.1|interpro:IPR018108|interpro:IPR023395|mint:P97700|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0008272"(sulfate transport)|go:"GO:0015116"(sulfate transmembrane transporter activity)|go:"GO:0015117"(thiosulfate transmembrane transporter activity)|go:"GO:0015131"(oxaloacetate transmembrane transporter activity)|go:"GO:0015139"(alpha-ketoglutarate transmembrane transporter activity)|go:"GO:0015140"(malate transmembrane transporter activity)|go:"GO:0015141"(succinate transmembrane transporter activity)|go:"GO:0015297"(antiporter activity)|go:"GO:0015709"(thiosulfate transport)|go:"GO:0015729"(oxaloacetate transport)|go:"GO:0016021"(integral component of membrane)|go:"GO:0035435"(phosphate ion transmembrane transport)|go:"GO:0071422"(succinate transmembrane transport)|go:"GO:0071423"(malate transmembrane transport)|reactome:R-RNO-70263	-	-	-	figure legend:st1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10116(rat-hippocampus)|taxid:10116(Rattus norvegicus hippocampal neurons)	-	2020/10/30	2020/10/30	rogid:DtE+ZXAZKdCMvUW5K+jXQ5bH07M10116	rogid:CwkgqsG6PQ93hzzwLedusjml4do10116	rigid:zzsc1zNhBb5nwIRPeFpYOKgC3M8	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q5XIE8	uniprotkb:P04897	intact:EBI-15348306|ensembl:ENSRNOP00000023037	intact:EBI-915875|ensembl:ENSRNOP00000022550	psi-mi:itm2b_rat(display_long)|uniprotkb:Itm2b(gene name)|psi-mi:Itm2b(display_short)|uniprotkb:Immature BRI2(gene name synonym)|uniprotkb:Transmembrane protein BRI(gene name synonym)	psi-mi:gnai2_rat(display_long)|uniprotkb:Adenylate cyclase-inhibiting G alpha protein(gene name synonym)|uniprotkb:Gnai2(gene name)|psi-mi:Gnai2(display_short)|uniprotkb:Gnai-2(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Martins et al. (2018)	imex:IM-28469|pubmed:29476059	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26440627|imex:IM-28469-5	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSRNOG00000016271(gene)|ensembl:ENSRNOT00000023037(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001540"(amyloid-beta binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0010008"(endosome membrane)|go:"GO:0030660"(Golgi-associated vesicle membrane)|go:"GO:0031301"(integral component of organelle membrane)|go:"GO:0042985"(negative regulation of amyloid precursor protein biosynthetic process)|interpro:IPR007084(BRICHOS)|interpro:IPR040145|mint:Q5XIE8|refseq:NP_001006964.1|rgd:620727	rgd:620243|refseq:NP_112297.1|refseq:XP_006243920.1|dip:DIP-607N|ensembl:ENSRNOG00000016592(gene)|ensembl:ENSRNOT00000022550(transcript)|go:"GO:0001664"(G protein-coupled receptor binding)|go:"GO:0001973"(G protein-coupled adenosine receptor signaling pathway)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005834"(heterotrimeric G-protein complex)|go:"GO:0005886"(plasma membrane)|go:"GO:0007049"(cell cycle)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0007188"(adenylate cyclase-modulating G protein-coupled receptor signaling pathway)|go:"GO:0007189"(adenylate cyclase-activating G protein-coupled receptor signaling pathway)|go:"GO:0007193"(adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway)|go:"GO:0007213"(G protein-coupled acetylcholine receptor signaling pathway)|go:"GO:0007214"(gamma-aminobutyric acid signaling pathway)|go:"GO:0008283"(cell population proliferation)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0016020"(membrane)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0030425"(dendrite)|go:"GO:0030496"(midbody)|go:"GO:0031683"(G-protein beta/gamma-subunit complex binding)|go:"GO:0032930"(positive regulation of superoxide anion generation)|go:"GO:0033864"("positive regulation of NAD(P)H oxidase activity")|go:"GO:0035810"(positive regulation of urine volume)|go:"GO:0035815"(positive regulation of renal sodium excretion)|go:"GO:0044297"(cell body)|go:"GO:0045121"(membrane raft)|go:"GO:0045202"(synapse)|go:"GO:0045955"(negative regulation of calcium ion-dependent exocytosis)|go:"GO:0046628"(positive regulation of insulin receptor signaling pathway)|go:"GO:0046872"(metal ion binding)|go:"GO:0050805"(negative regulation of synaptic transmission)|go:"GO:0051301"(cell division)|go:"GO:0051924"(regulation of calcium ion transport)|go:"GO:0070374"(positive regulation of ERK1 and ERK2 cascade)|go:"GO:0140199"(negative regulation of adenylate cyclase-activating adrenergic receptor signaling pathway involved in heart process)|go:"GO:1903614"(negative regulation of protein tyrosine phosphatase activity)|go:"GO:1904707"(positive regulation of vascular associated smooth muscle cell proliferation)|go:"GO:2000179"(positive regulation of neural precursor cell proliferation)|go:"GO:2001234"(negative regulation of apoptotic signaling pathway)|interpro:IPR001019("Guanine nucleotide binding protein (G-protein), alpha subunit")|interpro:IPR001408(G-protein alpha subunit, group I)|interpro:IPR011025(G protein alpha subunit, helical insertion)|interpro:IPR027417|mint:P04897|reactome:R-RNO-170670|reactome:R-RNO-392170|reactome:R-RNO-400042|reactome:R-RNO-418594|reactome:R-RNO-9009391	-	-	-	figure legend:st1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10116(rat-hippocampus)|taxid:10116(Rattus norvegicus hippocampal neurons)	-	2020/10/30	2020/10/30	rogid:DtE+ZXAZKdCMvUW5K+jXQ5bH07M10116	rogid:TXAwhCxZGiWn/waR1XaK92nByh410116	rigid:zzsc1zNhBb5nwIRPeFpYOKgC3M8	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q5XIE8	uniprotkb:Q68FX0	intact:EBI-15348306|ensembl:ENSRNOP00000023037	intact:EBI-1216909|ensembl:ENSRNOP00000009681	psi-mi:itm2b_rat(display_long)|uniprotkb:Itm2b(gene name)|psi-mi:Itm2b(display_short)|uniprotkb:Immature BRI2(gene name synonym)|uniprotkb:Transmembrane protein BRI(gene name synonym)	psi-mi:idh3b_rat(display_long)|uniprotkb:Idh3B(gene name)|psi-mi:Idh3B(display_short)|uniprotkb:Isocitric dehydrogenase subunit beta(gene name synonym)|uniprotkb:"NAD(+)-specific ICDH subunit beta"(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Martins et al. (2018)	imex:IM-28469|pubmed:29476059	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26440627|imex:IM-28469-5	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSRNOG00000016271(gene)|ensembl:ENSRNOT00000023037(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001540"(amyloid-beta binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0010008"(endosome membrane)|go:"GO:0030660"(Golgi-associated vesicle membrane)|go:"GO:0031301"(integral component of organelle membrane)|go:"GO:0042985"(negative regulation of amyloid precursor protein biosynthetic process)|interpro:IPR007084(BRICHOS)|interpro:IPR040145|mint:Q5XIE8|refseq:NP_001006964.1|rgd:620727	rgd:621881|refseq:NP_446033.1|go:"GO:0006099"(tricarboxylic acid cycle)|go:"GO:0006102"(isocitrate metabolic process)|go:"GO:0006103"(2-oxoglutarate metabolic process)|go:"GO:0006734"(NADH metabolic process)|go:"GO:0051287"(NAD binding)|interpro:IPR004434(Isocitrate dehydrogenase NAD-dependent, mitochondrial)|interpro:IPR019818|interpro:IPR024084|mint:Q68FX0|reactome:R-RNO-71403|ensembl:ENSRNOG00000007316(gene)|ensembl:ENSRNOT00000009681(transcript)|go:"GO:0000287"(magnesium ion binding)|go:"GO:0004449"("isocitrate dehydrogenase (NAD+) activity")|go:"GO:0005739"(mitochondrion)|go:"GO:0005962"("mitochondrial isocitrate dehydrogenase complex (NAD+)")	-	-	-	figure legend:st1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10116(rat-hippocampus)|taxid:10116(Rattus norvegicus hippocampal neurons)	-	2020/10/30	2020/10/30	rogid:DtE+ZXAZKdCMvUW5K+jXQ5bH07M10116	rogid:DAPnk1qn2Ksoy7kcoPBWiiBcwTQ10116	rigid:zzsc1zNhBb5nwIRPeFpYOKgC3M8	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q5XIE8	uniprotkb:P81155	intact:EBI-15348306|ensembl:ENSRNOP00000023037	intact:EBI-918064|uniprotkb:Q9JI32|ensembl:ENSRNOP00000018462|ensembl:ENSRNOP00000074839	psi-mi:itm2b_rat(display_long)|uniprotkb:Itm2b(gene name)|psi-mi:Itm2b(display_short)|uniprotkb:Immature BRI2(gene name synonym)|uniprotkb:Transmembrane protein BRI(gene name synonym)	psi-mi:vdac2_rat(display_long)|uniprotkb:Outer mitochondrial membrane protein porin 2(gene name synonym)|uniprotkb:B36-VDAC(gene name synonym)|uniprotkb:Vdac2(gene name)|psi-mi:Vdac2(display_short)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Martins et al. (2018)	imex:IM-28469|pubmed:29476059	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26440627|imex:IM-28469-5	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSRNOG00000016271(gene)|ensembl:ENSRNOT00000023037(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001540"(amyloid-beta binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0010008"(endosome membrane)|go:"GO:0030660"(Golgi-associated vesicle membrane)|go:"GO:0031301"(integral component of organelle membrane)|go:"GO:0042985"(negative regulation of amyloid precursor protein biosynthetic process)|interpro:IPR007084(BRICHOS)|interpro:IPR040145|mint:Q5XIE8|refseq:NP_001006964.1|rgd:620727	rgd:621576|refseq:NP_112644.1|refseq:XP_006251723.1|ensembl:ENSRNOG00000013505(gene)|ensembl:ENSRNOT00000018462(transcript)|ensembl:ENSRNOT00000086864(transcript)|go:"GO:0000166"(nucleotide binding)|go:"GO:0001669"(acrosomal vesicle)|go:"GO:0005739"(mitochondrion)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0006820"(anion transport)|go:"GO:0007339"(binding of sperm to zona pellucida)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0008308"(voltage-gated anion channel activity)|go:"GO:0015288"(porin activity)|go:"GO:0015485"(cholesterol binding)|go:"GO:0016020"(membrane)|go:"GO:0031210"(phosphatidylcholine binding)|go:"GO:0031966"(mitochondrial membrane)|go:"GO:0032272"(negative regulation of protein polymerization)|go:"GO:0042645"(mitochondrial nucleoid)|go:"GO:0046930"(pore complex)|go:"GO:0097001"(ceramide binding)|go:"GO:0097345"(mitochondrial outer membrane permeabilization)|go:"GO:2001243"(negative regulation of intrinsic apoptotic signaling pathway)|interpro:IPR001925(Porin, eukaryotic type)|interpro:IPR023614|interpro:IPR027246|interpro:IPR030277|mint:P81155|reactome:R-RNO-5689880	-	-	-	figure legend:st1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10116(rat-hippocampus)|taxid:10116(Rattus norvegicus hippocampal neurons)	-	2020/10/30	2020/10/30	rogid:DtE+ZXAZKdCMvUW5K+jXQ5bH07M10116	rogid:4hSm4QQy24guxjuUCy/7W97UqL810116	rigid:zzsc1zNhBb5nwIRPeFpYOKgC3M8	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q5XIE8	uniprotkb:Q9Z2L0	intact:EBI-15348306|ensembl:ENSRNOP00000023037	intact:EBI-920336|uniprotkb:A1L125|uniprotkb:Q3MHT8|uniprotkb:Q5M944|uniprotkb:Q5M972|uniprotkb:Q6IN28|uniprotkb:Q6P9W9|ensembl:ENSRNOP00000008477	psi-mi:itm2b_rat(display_long)|uniprotkb:Itm2b(gene name)|psi-mi:Itm2b(display_short)|uniprotkb:Immature BRI2(gene name synonym)|uniprotkb:Transmembrane protein BRI(gene name synonym)	psi-mi:vdac1_rat(display_long)|uniprotkb:Vdac1(gene name)|psi-mi:Vdac1(display_short)|uniprotkb:Outer mitochondrial membrane protein porin 1(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Martins et al. (2018)	imex:IM-28469|pubmed:29476059	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26440627|imex:IM-28469-5	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSRNOG00000016271(gene)|ensembl:ENSRNOT00000023037(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001540"(amyloid-beta binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0010008"(endosome membrane)|go:"GO:0030660"(Golgi-associated vesicle membrane)|go:"GO:0031301"(integral component of organelle membrane)|go:"GO:0042985"(negative regulation of amyloid precursor protein biosynthetic process)|interpro:IPR007084(BRICHOS)|interpro:IPR040145|mint:Q5XIE8|refseq:NP_001006964.1|rgd:620727	rgd:621575|refseq:NP_112643.1|ensembl:ENSRNOG00000006375(gene)|ensembl:ENSRNOT00000008477(transcript)|go:"GO:0000166"(nucleotide binding)|go:"GO:0001662"(behavioral fear response)|go:"GO:0032991"(protein-containing complex)|go:"GO:0042645"(mitochondrial nucleoid)|go:"GO:0042802"(identical protein binding)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045121"(membrane raft)|go:"GO:0097001"(ceramide binding)|go:"GO:0110099"(negative regulation of calcium import into the mitochondrion)|go:"GO:1901526"(positive regulation of mitophagy)|go:"GO:1903146"(regulation of autophagy of mitochondrion)|go:"GO:2000378"(negative regulation of reactive oxygen species metabolic process)|interpro:IPR001925(Porin, eukaryotic type)|interpro:IPR023614|interpro:IPR027246|interpro:IPR030270|mint:Q9Z2L0|reactome:R-RNO-5205685|reactome:R-RNO-5689880|reactome:R-RNO-70268|go:"GO:0031966"(mitochondrial membrane)|go:"GO:0005253"(anion channel activity)|go:"GO:0005262"(calcium channel activity)|go:"GO:0005739"(mitochondrion)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005757"(mitochondrial permeability transition pore complex)|go:"GO:0005886"(plasma membrane)|go:"GO:0006820"(anion transport)|go:"GO:0006851"(mitochondrial calcium ion transmembrane transport)|go:"GO:0006915"(apoptotic process)|go:"GO:0007268"(chemical synaptic transmission)|go:"GO:0007270"(neuron-neuron synaptic transmission)|go:"GO:0007612"(learning)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0008308"(voltage-gated anion channel activity)|go:"GO:0015288"(porin activity)|go:"GO:0015485"(cholesterol binding)|go:"GO:0016020"(membrane)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030855"(epithelial cell differentiation)|go:"GO:0031210"(phosphatidylcholine binding)|dip:DIP-37068N	-	-	-	figure legend:st1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10116(rat-hippocampus)|taxid:10116(Rattus norvegicus hippocampal neurons)	-	2020/10/30	2020/10/30	rogid:DtE+ZXAZKdCMvUW5K+jXQ5bH07M10116	rogid:9tTXatzG8BVX217+t0HLppj0oAY10116	rigid:zzsc1zNhBb5nwIRPeFpYOKgC3M8	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q5XIE8	uniprotkb:P0DJJ3	intact:EBI-15348306|ensembl:ENSRNOP00000023037	intact:EBI-26439465	psi-mi:itm2b_rat(display_long)|uniprotkb:Itm2b(gene name)|psi-mi:Itm2b(display_short)|uniprotkb:Immature BRI2(gene name synonym)|uniprotkb:Transmembrane protein BRI(gene name synonym)	psi-mi:sgip1_rat(display_long)|uniprotkb:Sgip1(gene name)|psi-mi:Sgip1(display_short)|uniprotkb:Endophilin-3-interacting protein(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Martins et al. (2018)	imex:IM-28469|pubmed:29476059	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26440627|imex:IM-28469-5	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSRNOG00000016271(gene)|ensembl:ENSRNOT00000023037(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001540"(amyloid-beta binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0010008"(endosome membrane)|go:"GO:0030660"(Golgi-associated vesicle membrane)|go:"GO:0031301"(integral component of organelle membrane)|go:"GO:0042985"(negative regulation of amyloid precursor protein biosynthetic process)|interpro:IPR007084(BRICHOS)|interpro:IPR040145|mint:Q5XIE8|refseq:NP_001006964.1|rgd:620727	go:"GO:0002021"(response to dietary excess)|go:"GO:0005543"(phospholipid binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0005905"(clathrin-coated pit)|go:"GO:0008017"(microtubule binding)|go:"GO:0015631"(tubulin binding)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0030122"(AP-2 adaptor complex)|go:"GO:0030136"(clathrin-coated vesicle)|go:"GO:0040018"(positive regulation of multicellular organism growth)|go:"GO:0042594"(response to starvation)|go:"GO:0043195"(terminal bouton)|go:"GO:0048260"(positive regulation of receptor-mediated endocytosis)|go:"GO:0048268"(clathrin coat assembly)|go:"GO:0072583"(clathrin-dependent endocytosis)|go:"GO:0097009"(energy homeostasis)|go:"GO:0098793"(presynapse)|go:"GO:1904000"(positive regulation of eating behavior)|go:"GO:2000253"(positive regulation of feeding behavior)|reactome:R-RNO-8856825|reactome:R-RNO-8856828|mint:P0DJJ3|refseq:XP_017449253.1|refseq:XP_017458523.1|interpro:IPR036168|interpro:IPR028565|interpro:IPR018808|interpro:IPR037984|rgd:1564957	-	-	-	figure legend:st1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10116(rat-hippocampus)|taxid:10116(Rattus norvegicus hippocampal neurons)	-	2020/10/30	2020/10/30	rogid:DtE+ZXAZKdCMvUW5K+jXQ5bH07M10116	rogid:J+vwy1Z+IAnYPPGLWNgA3SnnDzE10116	rigid:zzsc1zNhBb5nwIRPeFpYOKgC3M8	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q5XIE8	uniprotkb:Q99NA5	intact:EBI-15348306|ensembl:ENSRNOP00000023037	intact:EBI-919767	psi-mi:itm2b_rat(display_long)|uniprotkb:Itm2b(gene name)|psi-mi:Itm2b(display_short)|uniprotkb:Immature BRI2(gene name synonym)|uniprotkb:Transmembrane protein BRI(gene name synonym)	psi-mi:idh3a_rat(display_long)|uniprotkb:Idh3a(gene name)|psi-mi:Idh3a(display_short)|uniprotkb:Isocitric dehydrogenase subunit alpha(gene name synonym)|uniprotkb:"NAD(+)-specific ICDH subunit alpha"(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Martins et al. (2018)	imex:IM-28469|pubmed:29476059	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26440627|imex:IM-28469-5	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSRNOG00000016271(gene)|ensembl:ENSRNOT00000023037(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001540"(amyloid-beta binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0010008"(endosome membrane)|go:"GO:0030660"(Golgi-associated vesicle membrane)|go:"GO:0031301"(integral component of organelle membrane)|go:"GO:0042985"(negative regulation of amyloid precursor protein biosynthetic process)|interpro:IPR007084(BRICHOS)|interpro:IPR040145|mint:Q5XIE8|refseq:NP_001006964.1|rgd:620727	rgd:70889|refseq:NP_446090.1|interpro:IPR019818|interpro:IPR004434(Isocitrate dehydrogenase NAD-dependent, mitochondrial)|interpro:IPR024084|mint:Q99NA5|go:"GO:0000287"(magnesium ion binding)|go:"GO:0004449"("isocitrate dehydrogenase (NAD+) activity")|go:"GO:0005739"(mitochondrion)|go:"GO:0005962"("mitochondrial isocitrate dehydrogenase complex (NAD+)")|go:"GO:0006099"(tricarboxylic acid cycle)|go:"GO:0006102"(isocitrate metabolic process)|go:"GO:0006103"(2-oxoglutarate metabolic process)|go:"GO:0006734"(NADH metabolic process)|go:"GO:0051287"(NAD binding)|reactome:R-RNO-71403	-	-	-	figure legend:st1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10116(rat-hippocampus)|taxid:10116(Rattus norvegicus hippocampal neurons)	-	2020/10/30	2020/10/30	rogid:DtE+ZXAZKdCMvUW5K+jXQ5bH07M10116	rogid:hwr6FxZD9vcrVjwYX/Qoty2o6ME10116	rigid:zzsc1zNhBb5nwIRPeFpYOKgC3M8	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q5XIE8	uniprotkb:P19627	intact:EBI-15348306|ensembl:ENSRNOP00000023037	intact:EBI-26439434|ensembl:ENSRNOP00000001779	psi-mi:itm2b_rat(display_long)|uniprotkb:Itm2b(gene name)|psi-mi:Itm2b(display_short)|uniprotkb:Immature BRI2(gene name synonym)|uniprotkb:Transmembrane protein BRI(gene name synonym)	psi-mi:gnaz_rat(display_long)|uniprotkb:Gnaz(gene name)|psi-mi:Gnaz(display_short)|uniprotkb:"G(x) alpha chain"(gene name synonym)|uniprotkb:Gz-alpha(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Martins et al. (2018)	imex:IM-28469|pubmed:29476059	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26440627|imex:IM-28469-5	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSRNOG00000016271(gene)|ensembl:ENSRNOT00000023037(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001540"(amyloid-beta binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0010008"(endosome membrane)|go:"GO:0030660"(Golgi-associated vesicle membrane)|go:"GO:0031301"(integral component of organelle membrane)|go:"GO:0042985"(negative regulation of amyloid precursor protein biosynthetic process)|interpro:IPR007084(BRICHOS)|interpro:IPR040145|mint:Q5XIE8|refseq:NP_001006964.1|rgd:620727	ensembl:ENSRNOG00000001313(gene)|ensembl:ENSRNOT00000001779(transcript)|go:"GO:0001664"(G protein-coupled receptor binding)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005829"(cytosol)|go:"GO:0005834"(heterotrimeric G-protein complex)|go:"GO:0005886"(plasma membrane)|go:"GO:0007188"(adenylate cyclase-modulating G protein-coupled receptor signaling pathway)|go:"GO:0007193"(adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway)|go:"GO:0030425"(dendrite)|go:"GO:0031683"(G-protein beta/gamma-subunit complex binding)|go:"GO:0031821"(G protein-coupled serotonin receptor binding)|go:"GO:0044297"(cell body)|go:"GO:0046872"(metal ion binding)|go:"GO:0098664"(G protein-coupled serotonin receptor signaling pathway)|interpro:IPR001019("Guanine nucleotide binding protein (G-protein), alpha subunit")|interpro:IPR001408(G-protein alpha subunit, group I)|interpro:IPR011025(G protein alpha subunit, helical insertion)|interpro:IPR027417|mint:P19627|reactome:R-RNO-418597|refseq:NP_037321.1|refseq:XP_008771088.1|refseq:XP_008771089.1|refseq:XP_017457054.1|rgd:2717	-	-	-	figure legend:st1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10116(rat-hippocampus)|taxid:10116(Rattus norvegicus hippocampal neurons)	-	2020/10/30	2020/10/30	rogid:DtE+ZXAZKdCMvUW5K+jXQ5bH07M10116	rogid:fvi2QLvjnF52AQ7u5rw43TKLcQU10116	rigid:zzsc1zNhBb5nwIRPeFpYOKgC3M8	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q5XIE8	uniprotkb:P10824	intact:EBI-15348306|ensembl:ENSRNOP00000023037	intact:EBI-1026411|uniprotkb:Q45QN2|ensembl:ENSRNOP00000074036	psi-mi:itm2b_rat(display_long)|uniprotkb:Itm2b(gene name)|psi-mi:Itm2b(display_short)|uniprotkb:Immature BRI2(gene name synonym)|uniprotkb:Transmembrane protein BRI(gene name synonym)	psi-mi:gnai1_rat(display_long)|uniprotkb:Adenylate cyclase-inhibiting G alpha protein(gene name synonym)|uniprotkb:Gnai1(gene name)|psi-mi:Gnai1(display_short)|uniprotkb:Gnai-1(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Martins et al. (2018)	imex:IM-28469|pubmed:29476059	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26440627|imex:IM-28469-5	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSRNOG00000016271(gene)|ensembl:ENSRNOT00000023037(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001540"(amyloid-beta binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0010008"(endosome membrane)|go:"GO:0030660"(Golgi-associated vesicle membrane)|go:"GO:0031301"(integral component of organelle membrane)|go:"GO:0042985"(negative regulation of amyloid precursor protein biosynthetic process)|interpro:IPR007084(BRICHOS)|interpro:IPR040145|mint:Q5XIE8|refseq:NP_001006964.1|rgd:620727	rgd:2713|refseq:NP_037277.1|ensembl:ENSRNOG00000057096(gene)|ensembl:ENSRNOT00000091004(transcript)|go:"GO:0000287"(magnesium ion binding)|go:"GO:0001664"(G protein-coupled receptor binding)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005834"(heterotrimeric G-protein complex)|go:"GO:0005886"(plasma membrane)|go:"GO:0007049"(cell cycle)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0007188"(adenylate cyclase-modulating G protein-coupled receptor signaling pathway)|go:"GO:0016020"(membrane)|go:"GO:0019003"(GDP binding)|go:"GO:0030496"(midbody)|go:"GO:0031683"(G-protein beta/gamma-subunit complex binding)|go:"GO:0031821"(G protein-coupled serotonin receptor binding)|go:"GO:0032794"(GTPase activating protein binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0043949"(regulation of cAMP-mediated signaling)|go:"GO:0045121"(membrane raft)|go:"GO:0050805"(negative regulation of synaptic transmission)|go:"GO:0051301"(cell division)|go:"GO:0060236"(regulation of mitotic spindle organization)|go:"GO:0099738"(cell cortex region)|go:"GO:1904322"(cellular response to forskolin)|go:"GO:1904778"(positive regulation of protein localization to cell cortex)|interpro:IPR001019("Guanine nucleotide binding protein (G-protein), alpha subunit")|interpro:IPR001408(G-protein alpha subunit, group I)|interpro:IPR011025(G protein alpha subunit, helical insertion)|interpro:IPR027417|mint:P10824|rcsb pdb:1AGR|rcsb pdb:1AS0|go:"GO:0005634"(nucleus)|rcsb pdb:1AS2|rcsb pdb:1BH2|rcsb pdb:1BOF|rcsb pdb:1CIP|rcsb pdb:1FQJ|rcsb pdb:1FQK|rcsb pdb:1GDD|rcsb pdb:1GFI|rcsb pdb:1GG2|rcsb pdb:1GIA|rcsb pdb:1GIL|rcsb pdb:1GIT|rcsb pdb:1GP2|rcsb pdb:1SHZ|rcsb pdb:1SVK|rcsb pdb:1SVS|rcsb pdb:2BCJ|rcsb pdb:2ZJY|rcsb pdb:2ZJZ|rcsb pdb:3AH8|rcsb pdb:3D7M|rcsb pdb:3FFA|rcsb pdb:3FFB|rcsb pdb:3V00|rcsb pdb:4N0D|rcsb pdb:4N0E|rcsb pdb:4PAM|rcsb pdb:4PAN|rcsb pdb:4PAO|rcsb pdb:4PAQ|rcsb pdb:5KDL|rcsb pdb:5KDO|rcsb pdb:6M8H|rcsb pdb:6TYL|rcsb pdb:6UKT|rcsb pdb:6VMS|reactome:R-RNO-170670|reactome:R-RNO-392170|reactome:R-RNO-400042|reactome:R-RNO-418594|reactome:R-RNO-9009391|rcsb pdb:1AS3|dip:DIP-6073N	-	-	-	figure legend:st1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10116(rat-hippocampus)|taxid:10116(Rattus norvegicus hippocampal neurons)	-	2020/10/30	2020/10/30	rogid:DtE+ZXAZKdCMvUW5K+jXQ5bH07M10116	rogid:4L9LLDHqr9N7S/GgFjFkDvaUQuY10116	rigid:zzsc1zNhBb5nwIRPeFpYOKgC3M8	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q5XIE8	uniprotkb:P54311	intact:EBI-15348306|ensembl:ENSRNOP00000023037	intact:EBI-917779|uniprotkb:Q6Q8B1|uniprotkb:Q9QWG8|ensembl:ENSRNOP00000044340	psi-mi:itm2b_rat(display_long)|uniprotkb:Itm2b(gene name)|psi-mi:Itm2b(display_short)|uniprotkb:Immature BRI2(gene name synonym)|uniprotkb:Transmembrane protein BRI(gene name synonym)	psi-mi:gbb1_rat(display_long)|uniprotkb:Transducin beta chain 1(gene name synonym)|uniprotkb:Gnb1(gene name)|psi-mi:Gnb1(display_short)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Martins et al. (2018)	imex:IM-28469|pubmed:29476059	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26440627|imex:IM-28469-5	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSRNOG00000016271(gene)|ensembl:ENSRNOT00000023037(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001540"(amyloid-beta binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0010008"(endosome membrane)|go:"GO:0030660"(Golgi-associated vesicle membrane)|go:"GO:0031301"(integral component of organelle membrane)|go:"GO:0042985"(negative regulation of amyloid precursor protein biosynthetic process)|interpro:IPR007084(BRICHOS)|interpro:IPR040145|mint:Q5XIE8|refseq:NP_001006964.1|rgd:620727	rgd:2718|refseq:NP_112249.2|go:"GO:0001750"(photoreceptor outer segment)|go:"GO:0001917"(photoreceptor inner segment)|go:"GO:0003924"(GTPase activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005834"(heterotrimeric G-protein complex)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0007200"(phospholipase C-activating G protein-coupled receptor signaling pathway)|go:"GO:0007204"(positive regulation of cytosolic calcium ion concentration)|go:"GO:0008283"(cell population proliferation)|go:"GO:0010659"(cardiac muscle cell apoptotic process)|go:"GO:0030425"(dendrite)|go:"GO:0030507"(spectrin binding)|go:"GO:0031682"(G-protein gamma-subunit binding)|go:"GO:0042622"(photoreceptor outer segment membrane)|go:"GO:0044297"(cell body)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0047391"(alkylglycerophosphoethanolamine phosphodiesterase activity)|go:"GO:0050909"(sensory perception of taste)|ensembl:ENSRNOT00000041789(transcript)|ensembl:ENSRNOG00000016638(gene)|refseq:XP_008762557.1|refseq:XP_006239579.1|refseq:XP_017448634.1|refseq:XP_017448635.1|refseq:XP_017448636.1|refseq:XP_017448637.1|refseq:XP_017448638.1|dip:DIP-37029N|go:"GO:0051020"(GTPase binding)|go:"GO:0060041"(retina development in camera-type eye)|go:"GO:0071456"(cellular response to hypoxia)|interpro:IPR001632(G-protein, beta subunit)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR016346(Guanine nucleotide-binding protein, beta subunit)|interpro:IPR019775|interpro:IPR020472|interpro:IPR036322|mint:P54311|rcsb pdb:3SN6|rcsb pdb:5TDH|rcsb pdb:5VAI|rcsb pdb:6CMO|rcsb pdb:6LPB|rcsb pdb:6NBF|rcsb pdb:6NBH|rcsb pdb:6NBI|rcsb pdb:6WWZ|rcsb pdb:7BW0|rcsb pdb:7CZ5|rcsb pdb:7D3S|rcsb pdb:7LJC|rcsb pdb:7LJD|rcsb pdb:7MBX|rcsb pdb:7MBY|reactome:R-RNO-1296041|reactome:R-RNO-202040|reactome:R-RNO-2485179|reactome:R-RNO-381676|reactome:R-RNO-381753|reactome:R-RNO-392170|reactome:R-RNO-392451|reactome:R-RNO-400042|reactome:R-RNO-4086398|reactome:R-RNO-416476|reactome:R-RNO-418594|reactome:R-RNO-418597|reactome:R-RNO-420092|reactome:R-RNO-428930|reactome:R-RNO-432040|reactome:R-RNO-456926|reactome:R-RNO-6814122|reactome:R-RNO-8964616|reactome:R-RNO-997272	-	-	-	figure legend:st1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10116(rat-hippocampus)|taxid:10116(Rattus norvegicus hippocampal neurons)	-	2020/10/30	2020/10/30	rogid:DtE+ZXAZKdCMvUW5K+jXQ5bH07M10116	rogid:zP/G70MXiSQpzbyyWFTWrJFQENk10116	rigid:zzsc1zNhBb5nwIRPeFpYOKgC3M8	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q5XIE8	uniprotkb:P10888	intact:EBI-15348306|ensembl:ENSRNOP00000023037	intact:EBI-916287|ensembl:ENSRNOP00000024033	psi-mi:itm2b_rat(display_long)|uniprotkb:Itm2b(gene name)|psi-mi:Itm2b(display_short)|uniprotkb:Immature BRI2(gene name synonym)|uniprotkb:Transmembrane protein BRI(gene name synonym)	psi-mi:cox41_rat(display_long)|uniprotkb:Cox4i1(gene name)|psi-mi:Cox4i1(display_short)|uniprotkb:Cox4(gene name synonym)|uniprotkb:Cox4a(gene name synonym)|uniprotkb:Cytochrome c oxidase subunit IV isoform 1(gene name synonym)|uniprotkb:Cytochrome c oxidase polypeptide IV(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Martins et al. (2018)	imex:IM-28469|pubmed:29476059	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26440627|imex:IM-28469-5	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSRNOG00000016271(gene)|ensembl:ENSRNOT00000023037(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001540"(amyloid-beta binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0010008"(endosome membrane)|go:"GO:0030660"(Golgi-associated vesicle membrane)|go:"GO:0031301"(integral component of organelle membrane)|go:"GO:0042985"(negative regulation of amyloid precursor protein biosynthetic process)|interpro:IPR007084(BRICHOS)|interpro:IPR040145|mint:Q5XIE8|refseq:NP_001006964.1|rgd:620727	rgd:68374|refseq:NP_058898.1|ensembl:ENSRNOG00000017817(gene)|ensembl:ENSRNOT00000024033(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005751"(mitochondrial respiratory chain complex IV)|go:"GO:0005829"(cytosol)|go:"GO:0006123"(mitochondrial electron transport, cytochrome c to oxygen)|go:"GO:0007584"(response to nutrient)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016491"(oxidoreductase activity)|go:"GO:0031966"(mitochondrial membrane)|interpro:IPR004203(Cytochrome c oxidase subunit IV)|interpro:IPR013288(Cytochrome c oxidase subunit 4)|interpro:IPR036639|mint:P10888|reactome:R-RNO-5628897|reactome:R-RNO-611105|reactome:R-RNO-9707564	-	-	-	figure legend:st1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10116(rat-hippocampus)|taxid:10116(Rattus norvegicus hippocampal neurons)	-	2020/10/30	2020/10/30	rogid:DtE+ZXAZKdCMvUW5K+jXQ5bH07M10116	rogid:tNIBFX8yX4FTJHKAMI9P5dGA5hE10116	rigid:zzsc1zNhBb5nwIRPeFpYOKgC3M8	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q5XIE8	uniprotkb:Q9WVK7	intact:EBI-15348306|ensembl:ENSRNOP00000023037	intact:EBI-920220|ensembl:ENSRNOP00000014658	psi-mi:itm2b_rat(display_long)|uniprotkb:Itm2b(gene name)|psi-mi:Itm2b(display_short)|uniprotkb:Immature BRI2(gene name synonym)|uniprotkb:Transmembrane protein BRI(gene name synonym)	psi-mi:hcdh_rat(display_long)|uniprotkb:Hadh(gene name)|psi-mi:Hadh(display_short)|uniprotkb:Had(gene name synonym)|uniprotkb:Schad(gene name synonym)|uniprotkb:Short-chain 3-hydroxyacyl-CoA dehydrogenase(gene name synonym)|uniprotkb:Medium and short-chain L-3-hydroxyacyl-coenzyme A dehydrogenase(gene name synonym)|uniprotkb:Hadhsc(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Martins et al. (2018)	imex:IM-28469|pubmed:29476059	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26440627|imex:IM-28469-5	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSRNOG00000016271(gene)|ensembl:ENSRNOT00000023037(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001540"(amyloid-beta binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0010008"(endosome membrane)|go:"GO:0030660"(Golgi-associated vesicle membrane)|go:"GO:0031301"(integral component of organelle membrane)|go:"GO:0042985"(negative regulation of amyloid precursor protein biosynthetic process)|interpro:IPR007084(BRICHOS)|interpro:IPR040145|mint:Q5XIE8|refseq:NP_001006964.1|rgd:620727	rgd:69321|refseq:NP_476534.1|ensembl:ENSRNOG00000010697(gene)|ensembl:ENSRNOT00000014658(transcript)|go:"GO:0003857"(3-hydroxyacyl-CoA dehydrogenase activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0006635"(fatty acid beta-oxidation)|go:"GO:0009725"(response to hormone)|go:"GO:0014823"(response to activity)|go:"GO:0032868"(response to insulin)|go:"GO:0042493"|go:"GO:0042802"(identical protein binding)|go:"GO:0046676"(negative regulation of insulin secretion)|go:"GO:0050796"(regulation of insulin secretion)|go:"GO:0070403"(NAD+ binding)|go:"GO:0120162"(positive regulation of cold-induced thermogenesis)|interpro:IPR006108(3-hydroxyacyl-CoA dehydrogenase, C-terminal)|interpro:IPR006176(3-hydroxyacyl-CoA dehydrogenase, NAD binding)|interpro:IPR006180(3-hydroxyacyl-CoA dehydrogenase, conserved site)|interpro:IPR008927(6-phosphogluconate dehydrogenase, C-terminal-like)|interpro:IPR013328(Dehydrogenase, multihelical)|interpro:IPR022694|interpro:IPR036291|mint:Q9WVK7|reactome:R-RNO-77310|reactome:R-RNO-77346|reactome:R-RNO-77348|reactome:R-RNO-77350|reactome:R-RNO-77352	-	-	-	figure legend:st1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10116(rat-hippocampus)|taxid:10116(Rattus norvegicus hippocampal neurons)	-	2020/10/30	2020/10/30	rogid:DtE+ZXAZKdCMvUW5K+jXQ5bH07M10116	rogid:dqTvCevVe76aVj0jADypt3XzWa810116	rigid:zzsc1zNhBb5nwIRPeFpYOKgC3M8	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q5XIE8	uniprotkb:P29147	intact:EBI-15348306|ensembl:ENSRNOP00000023037	intact:EBI-21294686|uniprotkb:Q5U2Q2	psi-mi:itm2b_rat(display_long)|uniprotkb:Itm2b(gene name)|psi-mi:Itm2b(display_short)|uniprotkb:Immature BRI2(gene name synonym)|uniprotkb:Transmembrane protein BRI(gene name synonym)	psi-mi:bdh_rat(display_long)|uniprotkb:Bdh1(gene name)|psi-mi:Bdh1(display_short)|uniprotkb:Bdh(gene name synonym)|uniprotkb:3-hydroxybutyrate dehydrogenase(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Martins et al. (2018)	imex:IM-28469|pubmed:29476059	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26440627|imex:IM-28469-5	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSRNOG00000016271(gene)|ensembl:ENSRNOT00000023037(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001540"(amyloid-beta binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0010008"(endosome membrane)|go:"GO:0030660"(Golgi-associated vesicle membrane)|go:"GO:0031301"(integral component of organelle membrane)|go:"GO:0042985"(negative regulation of amyloid precursor protein biosynthetic process)|interpro:IPR007084(BRICHOS)|interpro:IPR040145|mint:Q5XIE8|refseq:NP_001006964.1|rgd:620727	mint:P29147|go:"GO:0001889"(liver development)|go:"GO:0003858"(3-hydroxybutyrate dehydrogenase activity)|go:"GO:0005543"(phospholipid binding)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0007420"(brain development)|go:"GO:0007584"(response to nutrient)|go:"GO:0008152"(metabolic process)|go:"GO:0009636"(response to toxic substance)|go:"GO:0009725"(response to hormone)|go:"GO:0032355"(response to estradiol)|go:"GO:0032868"(response to insulin)|go:"GO:0042493"|go:"GO:0042594"(response to starvation)|go:"GO:0045471"(response to ethanol)|go:"GO:0046686"(response to cadmium ion)|go:"GO:0051412"(response to corticosterone)|go:"GO:0060416"(response to growth hormone)|go:"GO:0060612"(adipose tissue development)|go:"GO:0099617"(matrix side of mitochondrial inner membrane)|reactome:R-RNO-77108|reactome:R-RNO-77111|refseq:NP_446447.2|refseq:XP_006248540.1|refseq:XP_008766913.1|interpro:IPR036291|interpro:IPR020904|interpro:IPR002347(Glucose/ribitol dehydrogenase)|rgd:620131	-	-	-	figure legend:st1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10116(rat-hippocampus)|taxid:10116(Rattus norvegicus hippocampal neurons)	-	2020/10/30	2020/10/30	rogid:DtE+ZXAZKdCMvUW5K+jXQ5bH07M10116	rogid:Vv9XLbzySx2nN+g5Joww7cyDgOM10116	rigid:zzsc1zNhBb5nwIRPeFpYOKgC3M8	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q5XIE8	uniprotkb:P07936	intact:EBI-15348306|ensembl:ENSRNOP00000023037	intact:EBI-26438795|ensembl:ENSRNOP00000002091|uniprotkb:A0JPM4	psi-mi:itm2b_rat(display_long)|uniprotkb:Itm2b(gene name)|psi-mi:Itm2b(display_short)|uniprotkb:Immature BRI2(gene name synonym)|uniprotkb:Transmembrane protein BRI(gene name synonym)	psi-mi:neum_rat(display_long)|uniprotkb:Gap43(gene name)|psi-mi:Gap43(display_short)|uniprotkb:Axonal membrane protein GAP-43(gene name synonym)|uniprotkb:Growth-associated protein 43(gene name synonym)|uniprotkb:Protein F1(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Martins et al. (2018)	imex:IM-28469|pubmed:29476059	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26440882|imex:IM-28469-7	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSRNOG00000016271(gene)|ensembl:ENSRNOT00000023037(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001540"(amyloid-beta binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0010008"(endosome membrane)|go:"GO:0030660"(Golgi-associated vesicle membrane)|go:"GO:0031301"(integral component of organelle membrane)|go:"GO:0042985"(negative regulation of amyloid precursor protein biosynthetic process)|interpro:IPR007084(BRICHOS)|interpro:IPR040145|mint:Q5XIE8|refseq:NP_001006964.1|rgd:620727	ensembl:ENSRNOG00000001528(gene)|ensembl:ENSRNOT00000002091(transcript)|go:"GO:0001786"(phosphatidylserine binding)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0007399"(nervous system development)|go:"GO:0007411"(axon guidance)|go:"GO:0010001"(glial cell differentiation)|go:"GO:0014069"(postsynaptic density)|go:"GO:0016198"(axon choice point recognition)|go:"GO:0030424"(axon)|go:"GO:0030425"(dendrite)|go:"GO:0030426"(growth cone)|go:"GO:0031103"(axon regeneration)|go:"GO:0031527"(filopodium membrane)|go:"GO:0032584"(growth cone membrane)|go:"GO:0035727"(lysophosphatidic acid binding)|go:"GO:0040008"(regulation of growth)|go:"GO:0042246"(tissue regeneration)|go:"GO:0043204"(perikaryon)|go:"GO:0045165"(cell fate commitment)|go:"GO:0051489"(regulation of filopodium assembly)|go:"GO:0071944"(cell periphery)|go:"GO:0098982"(GABA-ergic synapse)|go:"GO:0099150"(regulation of postsynaptic specialization assembly)|go:"GO:1901981"(phosphatidylinositol phosphate binding)|interpro:IPR000048(IQ calmodulin-binding region)|interpro:IPR001422("Neuromodulin (GAP-43)")|interpro:IPR017454("Neuromodulin (GAP-43), C-terminal")|interpro:IPR018243|interpro:IPR018947|interpro:IPR033137|mint:P07936|reactome:R-RNO-373760|refseq:NP_058891.1|rgd:62071	-	-	-	figure legend:F5A SF3|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10116(rat-brain-cortex)|taxid:10116(Rattus norvegicus brain cortex)	-	2020/10/30	2020/10/30	rogid:DtE+ZXAZKdCMvUW5K+jXQ5bH07M10116	rogid:PI3nUZq+f76xlzN4ebj0gW06/XI10116	rigid:n3vrzqqknGwCPwBrimbYEQZ6gR4	false	-	-	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:Q5XIE8	uniprotkb:P07825	intact:EBI-15348306|ensembl:ENSRNOP00000023037	intact:EBI-976085|uniprotkb:Q499R3	psi-mi:itm2b_rat(display_long)|uniprotkb:Itm2b(gene name)|psi-mi:Itm2b(display_short)|uniprotkb:Immature BRI2(gene name synonym)|uniprotkb:Transmembrane protein BRI(gene name synonym)	psi-mi:syph_rat(display_long)|uniprotkb:Major synaptic vesicle protein p38(gene name synonym)|uniprotkb:Syp(gene name)|psi-mi:Syp(display_short)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Martins et al. (2018)	imex:IM-28469|pubmed:29476059	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26440882|imex:IM-28469-7	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSRNOG00000016271(gene)|ensembl:ENSRNOT00000023037(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001540"(amyloid-beta binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0010008"(endosome membrane)|go:"GO:0030660"(Golgi-associated vesicle membrane)|go:"GO:0031301"(integral component of organelle membrane)|go:"GO:0042985"(negative regulation of amyloid precursor protein biosynthetic process)|interpro:IPR007084(BRICHOS)|interpro:IPR040145|mint:Q5XIE8|refseq:NP_001006964.1|rgd:620727	go:"GO:0030285"(integral component of synaptic vesicle membrane)|go:"GO:0048169"(regulation of long-term neuronal synaptic plasticity)|go:"GO:0030672"(synaptic vesicle membrane)|go:"GO:0048172"(regulation of short-term neuronal synaptic plasticity)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0031594"(neuromuscular junction)|go:"GO:0048488"(synaptic vesicle endocytosis)|go:"GO:0048786"(presynaptic active zone)|go:"GO:0060076"(excitatory synapse)|go:"GO:0032991"(protein-containing complex)|go:"GO:0071310"(cellular response to organic substance)|go:"GO:0042169"(SH2 domain binding)|go:"GO:0098685"(Schaffer collateral - CA1 synapse)|go:"GO:0042734"(presynaptic membrane)|go:"GO:1904645"(response to amyloid-beta)|go:"GO:2000300"(regulation of synaptic vesicle exocytosis)|go:"GO:0042802"(identical protein binding)|go:"GO:0043005"(neuron projection)|go:"GO:0043195"(terminal bouton)|go:"GO:2000474"(regulation of opioid receptor signaling pathway)|go:"GO:0043229"(intracellular organelle)|go:"GO:0044306"(neuron projection terminus)|go:"GO:0044309"(neuron spine)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045202"(synapse)|go:"GO:0048168"(regulation of neuronal synaptic plasticity)|go:"GO:0000149"(SNARE binding)|go:"GO:0006897"(endocytosis)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0014069"(postsynaptic density)|go:"GO:0015485"(cholesterol binding)|go:"GO:0016020"(membrane)|go:"GO:0017075"(syntaxin-1 binding)|go:"GO:0019904"(protein domain specific binding)|rgd:3802|refseq:NP_036796.1|interpro:IPR008253(Marvel)|interpro:IPR001285(Synaptophysin/synaptoporin)|interpro:IPR028714|mint:P07825	-	-	-	figure legend:F5A SF3|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10116(rat-brain-cortex)|taxid:10116(Rattus norvegicus brain cortex)	-	2020/10/30	2020/10/30	rogid:DtE+ZXAZKdCMvUW5K+jXQ5bH07M10116	rogid:nG9lA5IrA7dLVQ2QlJ7VhtruLLg10116	rigid:n3vrzqqknGwCPwBrimbYEQZ6gR4	false	-	-	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:Q5XIE8	uniprotkb:P31016	intact:EBI-15348306|ensembl:ENSRNOP00000023037	intact:EBI-375655|uniprotkb:P97631|ensembl:ENSRNOP00000059045	psi-mi:itm2b_rat(display_long)|uniprotkb:Itm2b(gene name)|psi-mi:Itm2b(display_short)|uniprotkb:Immature BRI2(gene name synonym)|uniprotkb:Transmembrane protein BRI(gene name synonym)	psi-mi:dlg4_rat(display_long)|uniprotkb:Dlg4(gene name)|psi-mi:Dlg4(display_short)|uniprotkb:Dlgh4(gene name synonym)|uniprotkb:Postsynaptic density protein 95(gene name synonym)|uniprotkb:Synapse-associated protein 90(gene name synonym)|uniprotkb:Psd95(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Martins et al. (2018)	imex:IM-28469|pubmed:29476059	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26440882|imex:IM-28469-7	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSRNOG00000016271(gene)|ensembl:ENSRNOT00000023037(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001540"(amyloid-beta binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0010008"(endosome membrane)|go:"GO:0030660"(Golgi-associated vesicle membrane)|go:"GO:0031301"(integral component of organelle membrane)|go:"GO:0042985"(negative regulation of amyloid precursor protein biosynthetic process)|interpro:IPR007084(BRICHOS)|interpro:IPR040145|mint:Q5XIE8|refseq:NP_001006964.1|rgd:620727	go:"GO:0030165"(PDZ domain binding)|go:"GO:0030425"(dendrite)|go:"GO:0030863"(cortical cytoskeleton)|go:"GO:0031234"(extrinsic component of cytoplasmic side of plasma membrane)|go:"GO:0031594"(neuromuscular junction)|go:"GO:0031697"(beta-1 adrenergic receptor binding)|go:"GO:0031698"(beta-2 adrenergic receptor binding)|go:"GO:0031748"(D1 dopamine receptor binding)|go:"GO:0031812"(P2Y1 nucleotide receptor binding)|go:"GO:0032281"(AMPA glutamate receptor complex)|go:"GO:0032839"(dendrite cytoplasm)|go:"GO:0033130"(acetylcholine receptor binding)|go:"GO:0035176"(social behavior)|go:"GO:0035254"(glutamate receptor binding)|go:"GO:0035255"(ionotropic glutamate receptor binding)|go:"GO:0035418"(protein localization to synapse)|go:"GO:0035641"(locomotory exploration behavior)|go:"GO:0035865"(cellular response to potassium ion)|go:"GO:0043005"(neuron projection)|go:"GO:0043113"(receptor clustering)|go:"GO:0043197"(dendritic spine)|go:"GO:0044224"(juxtaparanode region of axon)|go:"GO:0044300"(cerebellar mossy fiber)|go:"GO:0044306"(neuron projection terminus)|go:"GO:0044309"(neuron spine)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045161"(neuronal ion channel clustering)|go:"GO:0045184"(establishment of protein localization)|go:"GO:0045202"(synapse)|go:"GO:0045211"(postsynaptic membrane)|go:"GO:0048168"(regulation of neuronal synaptic plasticity)|go:"GO:0048169"(regulation of long-term neuronal synaptic plasticity)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0050806"(positive regulation of synaptic transmission)|go:"GO:0050885"(neuromuscular process controlling balance)|go:"GO:0060076"(excitatory synapse)|go:"GO:0060997"(dendritic spine morphogenesis)|go:"GO:0061098"(positive regulation of protein tyrosine kinase activity)|go:"GO:0099031"(anchored component of postsynaptic density membrane)|go:"GO:0065003"(protein-containing complex assembly)|go:"GO:0071625"(vocalization behavior)|go:"GO:0071944"(cell periphery)|go:"GO:0097060"(synaptic membrane)|go:"GO:0097061"(dendritic spine organization)|go:"GO:0097109"(neuroligin family protein binding)|go:"GO:0099645"(neurotransmitter receptor localization to postsynaptic specialization membrane)|go:"GO:0150012"(positive regulation of neuron projection arborization)|go:"GO:0097110"(scaffold protein binding)|go:"GO:1904719"(positive regulation of AMPA glutamate receptor clustering)|go:"GO:0097113"(AMPA glutamate receptor clustering)|go:"GO:0097120"(receptor localization to synapse)|go:"GO:0098609"(cell-cell adhesion)|go:"GO:0098794"(postsynapse)|go:"GO:0098839"(postsynaptic density membrane)|go:"GO:0098919"(structural constituent of postsynaptic density)|go:"GO:0098970"(postsynaptic neurotransmitter receptor diffusion trapping)|go:"GO:2000310"(regulation of NMDA receptor activity)|go:"GO:2000463"(positive regulation of excitatory postsynaptic potential)|go:"GO:2000821"(regulation of grooming behavior)|interpro:IPR001452(Src homology-3)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR008144(Guanylate kinase)|interpro:IPR008145(Guanylate kinase/L-type calcium channel region)|rcsb pdb:1TP3|interpro:IPR016313("Membrane-associated guanylate kinase (MAGUK) scaffold protein")|interpro:IPR019583|interpro:IPR019590|interpro:IPR020590|interpro:IPR027417|interpro:IPR036028|interpro:IPR036034|mint:P31016|rcsb pdb:1BE9|rcsb pdb:1BFE|rcsb pdb:1IU0|rcsb pdb:1IU2|rcsb pdb:1JXM|rcsb pdb:1JXO|rcsb pdb:1KJW|rcsb pdb:1QLC|rcsb pdb:1RGR|rcsb pdb:5MZ7|rcsb pdb:5W72|rcsb pdb:5YPO|rcsb pdb:5YPR|rcsb pdb:7CQF|reactome:R-RNO-399719|reactome:R-RNO-438066|reactome:R-RNO-451308|reactome:R-RNO-5625900|reactome:R-RNO-5673001|reactome:R-RNO-5682910|reactome:R-RNO-6794361|reactome:R-RNO-8849932|rcsb pdb:1TP5|rcsb pdb:1TQ3|rcsb pdb:2KA9|rcsb pdb:2MHO|rcsb pdb:2XKX|rcsb pdb:3GSL|rcsb pdb:3WP0|rcsb pdb:3WP1|rcsb pdb:5B64|rcsb pdb:5D13|rcsb pdb:5GNV|rcsb pdb:5HDY|rcsb pdb:5HEB|rcsb pdb:5HED|rcsb pdb:5HET|rcsb pdb:5HEY|rcsb pdb:5HF1|rcsb pdb:5HF4|rcsb pdb:5HFB|rcsb pdb:5HFC|rcsb pdb:5HFD|rcsb pdb:5HFE|rcsb pdb:5HFF|ensembl:ENSRNOG00000018526(gene)|ensembl:ENSRNOT00000068493(transcript)|go:"GO:0002091"(negative regulation of receptor internalization)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005109"(frizzled binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0007204"(positive regulation of cytosolic calcium ion concentration)|go:"GO:0007268"(chemical synaptic transmission)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008328"(ionotropic glutamate receptor complex)|go:"GO:0014069"(postsynaptic density)|go:"GO:0016020"(membrane)|go:"GO:0016188"(synaptic vesicle maturation)|go:"GO:0019865"(immunoglobulin binding)|go:"GO:0019894"(kinesin binding)|go:"GO:0019900"(kinase binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0019903"(protein phosphatase binding)|go:"GO:0030054"(cell junction)|rgd:68424|refseq:NP_062567.1|dip:DIP-29264N	-	-	-	figure legend:F5A SF3|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10116(rat-brain-cortex)|taxid:10116(Rattus norvegicus brain cortex)	-	2020/10/30	2020/10/30	rogid:DtE+ZXAZKdCMvUW5K+jXQ5bH07M10116	rogid:4oWbxT/HVvWQqdbFqt3htRuQNpw10116	rigid:n3vrzqqknGwCPwBrimbYEQZ6gR4	false	-	-	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:P31016	uniprotkb:Q5XIE8	intact:EBI-375655|uniprotkb:P97631|ensembl:ENSRNOP00000059045	intact:EBI-15348306|ensembl:ENSRNOP00000023037	psi-mi:dlg4_rat(display_long)|uniprotkb:Dlg4(gene name)|psi-mi:Dlg4(display_short)|uniprotkb:Dlgh4(gene name synonym)|uniprotkb:Postsynaptic density protein 95(gene name synonym)|uniprotkb:Synapse-associated protein 90(gene name synonym)|uniprotkb:Psd95(gene name synonym)	psi-mi:itm2b_rat(display_long)|uniprotkb:Itm2b(gene name)|psi-mi:Itm2b(display_short)|uniprotkb:Immature BRI2(gene name synonym)|uniprotkb:Transmembrane protein BRI(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Martins et al. (2018)	imex:IM-28469|pubmed:29476059	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26440888|imex:IM-28469-9	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	go:"GO:0030165"(PDZ domain binding)|go:"GO:0030425"(dendrite)|go:"GO:0030863"(cortical cytoskeleton)|go:"GO:0031234"(extrinsic component of cytoplasmic side of plasma membrane)|go:"GO:0031594"(neuromuscular junction)|go:"GO:0031697"(beta-1 adrenergic receptor binding)|go:"GO:0031698"(beta-2 adrenergic receptor binding)|go:"GO:0031748"(D1 dopamine receptor binding)|go:"GO:0031812"(P2Y1 nucleotide receptor binding)|go:"GO:0032281"(AMPA glutamate receptor complex)|go:"GO:0032839"(dendrite cytoplasm)|go:"GO:0033130"(acetylcholine receptor binding)|go:"GO:0035176"(social behavior)|go:"GO:0035254"(glutamate receptor binding)|go:"GO:0035255"(ionotropic glutamate receptor binding)|go:"GO:0035418"(protein localization to synapse)|go:"GO:0035641"(locomotory exploration behavior)|go:"GO:0035865"(cellular response to potassium ion)|go:"GO:0043005"(neuron projection)|go:"GO:0043113"(receptor clustering)|go:"GO:0043197"(dendritic spine)|go:"GO:0044224"(juxtaparanode region of axon)|go:"GO:0044300"(cerebellar mossy fiber)|go:"GO:0044306"(neuron projection terminus)|go:"GO:0044309"(neuron spine)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045161"(neuronal ion channel clustering)|go:"GO:0045184"(establishment of protein localization)|go:"GO:0045202"(synapse)|go:"GO:0045211"(postsynaptic membrane)|go:"GO:0048168"(regulation of neuronal synaptic plasticity)|go:"GO:0048169"(regulation of long-term neuronal synaptic plasticity)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0050806"(positive regulation of synaptic transmission)|go:"GO:0050885"(neuromuscular process controlling balance)|go:"GO:0060076"(excitatory synapse)|go:"GO:0060997"(dendritic spine morphogenesis)|go:"GO:0061098"(positive regulation of protein tyrosine kinase activity)|go:"GO:0099031"(anchored component of postsynaptic density membrane)|go:"GO:0065003"(protein-containing complex assembly)|go:"GO:0071625"(vocalization behavior)|go:"GO:0071944"(cell periphery)|go:"GO:0097060"(synaptic membrane)|go:"GO:0097061"(dendritic spine organization)|go:"GO:0097109"(neuroligin family protein binding)|go:"GO:0099645"(neurotransmitter receptor localization to postsynaptic specialization membrane)|go:"GO:0150012"(positive regulation of neuron projection arborization)|go:"GO:0097110"(scaffold protein binding)|go:"GO:1904719"(positive regulation of AMPA glutamate receptor clustering)|go:"GO:0097113"(AMPA glutamate receptor clustering)|go:"GO:0097120"(receptor localization to synapse)|go:"GO:0098609"(cell-cell adhesion)|go:"GO:0098794"(postsynapse)|go:"GO:0098839"(postsynaptic density membrane)|go:"GO:0098919"(structural constituent of postsynaptic density)|go:"GO:0098970"(postsynaptic neurotransmitter receptor diffusion trapping)|go:"GO:2000310"(regulation of NMDA receptor activity)|go:"GO:2000463"(positive regulation of excitatory postsynaptic potential)|go:"GO:2000821"(regulation of grooming behavior)|interpro:IPR001452(Src homology-3)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR008144(Guanylate kinase)|interpro:IPR008145(Guanylate kinase/L-type calcium channel region)|rcsb pdb:1TP3|interpro:IPR016313("Membrane-associated guanylate kinase (MAGUK) scaffold protein")|interpro:IPR019583|interpro:IPR019590|interpro:IPR020590|interpro:IPR027417|interpro:IPR036028|interpro:IPR036034|mint:P31016|rcsb pdb:1BE9|rcsb pdb:1BFE|rcsb pdb:1IU0|rcsb pdb:1IU2|rcsb pdb:1JXM|rcsb pdb:1JXO|rcsb pdb:1KJW|rcsb pdb:1QLC|rcsb pdb:1RGR|rcsb pdb:5MZ7|rcsb pdb:5W72|rcsb pdb:5YPO|rcsb pdb:5YPR|rcsb pdb:7CQF|reactome:R-RNO-399719|reactome:R-RNO-438066|reactome:R-RNO-451308|reactome:R-RNO-5625900|reactome:R-RNO-5673001|reactome:R-RNO-5682910|reactome:R-RNO-6794361|reactome:R-RNO-8849932|rcsb pdb:1TP5|rcsb pdb:1TQ3|rcsb pdb:2KA9|rcsb pdb:2MHO|rcsb pdb:2XKX|rcsb pdb:3GSL|rcsb pdb:3WP0|rcsb pdb:3WP1|rcsb pdb:5B64|rcsb pdb:5D13|rcsb pdb:5GNV|rcsb pdb:5HDY|rcsb pdb:5HEB|rcsb pdb:5HED|rcsb pdb:5HET|rcsb pdb:5HEY|rcsb pdb:5HF1|rcsb pdb:5HF4|rcsb pdb:5HFB|rcsb pdb:5HFC|rcsb pdb:5HFD|rcsb pdb:5HFE|rcsb pdb:5HFF|ensembl:ENSRNOG00000018526(gene)|ensembl:ENSRNOT00000068493(transcript)|go:"GO:0002091"(negative regulation of receptor internalization)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005109"(frizzled binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0007204"(positive regulation of cytosolic calcium ion concentration)|go:"GO:0007268"(chemical synaptic transmission)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008328"(ionotropic glutamate receptor complex)|go:"GO:0014069"(postsynaptic density)|go:"GO:0016020"(membrane)|go:"GO:0016188"(synaptic vesicle maturation)|go:"GO:0019865"(immunoglobulin binding)|go:"GO:0019894"(kinesin binding)|go:"GO:0019900"(kinase binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0019903"(protein phosphatase binding)|go:"GO:0030054"(cell junction)|rgd:68424|refseq:NP_062567.1|dip:DIP-29264N	ensembl:ENSRNOG00000016271(gene)|ensembl:ENSRNOT00000023037(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001540"(amyloid-beta binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0010008"(endosome membrane)|go:"GO:0030660"(Golgi-associated vesicle membrane)|go:"GO:0031301"(integral component of organelle membrane)|go:"GO:0042985"(negative regulation of amyloid precursor protein biosynthetic process)|interpro:IPR007084(BRICHOS)|interpro:IPR040145|mint:Q5XIE8|refseq:NP_001006964.1|rgd:620727	-	-	-	figure legend:F5B SF3|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10116(rat-brain-cortex)|taxid:10116(Rattus norvegicus brain cortex)	-	2020/10/30	2020/10/30	rogid:4oWbxT/HVvWQqdbFqt3htRuQNpw10116	rogid:DtE+ZXAZKdCMvUW5K+jXQ5bH07M10116	rigid:VS3eJiCRlwXB0WXjFakvk6eRHQg	false	-	-	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:Q5XIE8	uniprotkb:P07825	intact:EBI-15348306|ensembl:ENSRNOP00000023037	intact:EBI-976085|uniprotkb:Q499R3	psi-mi:itm2b_rat(display_long)|uniprotkb:Itm2b(gene name)|psi-mi:Itm2b(display_short)|uniprotkb:Immature BRI2(gene name synonym)|uniprotkb:Transmembrane protein BRI(gene name synonym)	psi-mi:syph_rat(display_long)|uniprotkb:Major synaptic vesicle protein p38(gene name synonym)|uniprotkb:Syp(gene name)|psi-mi:Syp(display_short)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Martins et al. (2018)	imex:IM-28469|pubmed:29476059	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26440894|imex:IM-28469-11	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSRNOG00000016271(gene)|ensembl:ENSRNOT00000023037(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001540"(amyloid-beta binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0010008"(endosome membrane)|go:"GO:0030660"(Golgi-associated vesicle membrane)|go:"GO:0031301"(integral component of organelle membrane)|go:"GO:0042985"(negative regulation of amyloid precursor protein biosynthetic process)|interpro:IPR007084(BRICHOS)|interpro:IPR040145|mint:Q5XIE8|refseq:NP_001006964.1|rgd:620727	go:"GO:0030285"(integral component of synaptic vesicle membrane)|go:"GO:0048169"(regulation of long-term neuronal synaptic plasticity)|go:"GO:0030672"(synaptic vesicle membrane)|go:"GO:0048172"(regulation of short-term neuronal synaptic plasticity)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0031594"(neuromuscular junction)|go:"GO:0048488"(synaptic vesicle endocytosis)|go:"GO:0048786"(presynaptic active zone)|go:"GO:0060076"(excitatory synapse)|go:"GO:0032991"(protein-containing complex)|go:"GO:0071310"(cellular response to organic substance)|go:"GO:0042169"(SH2 domain binding)|go:"GO:0098685"(Schaffer collateral - CA1 synapse)|go:"GO:0042734"(presynaptic membrane)|go:"GO:1904645"(response to amyloid-beta)|go:"GO:2000300"(regulation of synaptic vesicle exocytosis)|go:"GO:0042802"(identical protein binding)|go:"GO:0043005"(neuron projection)|go:"GO:0043195"(terminal bouton)|go:"GO:2000474"(regulation of opioid receptor signaling pathway)|go:"GO:0043229"(intracellular organelle)|go:"GO:0044306"(neuron projection terminus)|go:"GO:0044309"(neuron spine)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045202"(synapse)|go:"GO:0048168"(regulation of neuronal synaptic plasticity)|go:"GO:0000149"(SNARE binding)|go:"GO:0006897"(endocytosis)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0014069"(postsynaptic density)|go:"GO:0015485"(cholesterol binding)|go:"GO:0016020"(membrane)|go:"GO:0017075"(syntaxin-1 binding)|go:"GO:0019904"(protein domain specific binding)|rgd:3802|refseq:NP_036796.1|interpro:IPR008253(Marvel)|interpro:IPR001285(Synaptophysin/synaptoporin)|interpro:IPR028714|mint:P07825	-	-	-	figure legend:F5C SF3|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10116(rat-brain-cortex)|taxid:10116(Rattus norvegicus brain cortex)	-	2020/10/30	2020/10/30	rogid:DtE+ZXAZKdCMvUW5K+jXQ5bH07M10116	rogid:nG9lA5IrA7dLVQ2QlJ7VhtruLLg10116	rigid:fC+Fe6CaBaa1OdJM8OjHGTlsrYo	false	-	-	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:Q5XIE8	uniprotkb:P07936	intact:EBI-15348306|ensembl:ENSRNOP00000023037	intact:EBI-26438795|ensembl:ENSRNOP00000002091|uniprotkb:A0JPM4	psi-mi:itm2b_rat(display_long)|uniprotkb:Itm2b(gene name)|psi-mi:Itm2b(display_short)|uniprotkb:Immature BRI2(gene name synonym)|uniprotkb:Transmembrane protein BRI(gene name synonym)	psi-mi:neum_rat(display_long)|uniprotkb:Gap43(gene name)|psi-mi:Gap43(display_short)|uniprotkb:Axonal membrane protein GAP-43(gene name synonym)|uniprotkb:Growth-associated protein 43(gene name synonym)|uniprotkb:Protein F1(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Martins et al. (2018)	imex:IM-28469|pubmed:29476059	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26440898|imex:IM-28469-13	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSRNOG00000016271(gene)|ensembl:ENSRNOT00000023037(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001540"(amyloid-beta binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0010008"(endosome membrane)|go:"GO:0030660"(Golgi-associated vesicle membrane)|go:"GO:0031301"(integral component of organelle membrane)|go:"GO:0042985"(negative regulation of amyloid precursor protein biosynthetic process)|interpro:IPR007084(BRICHOS)|interpro:IPR040145|mint:Q5XIE8|refseq:NP_001006964.1|rgd:620727	ensembl:ENSRNOG00000001528(gene)|ensembl:ENSRNOT00000002091(transcript)|go:"GO:0001786"(phosphatidylserine binding)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0007399"(nervous system development)|go:"GO:0007411"(axon guidance)|go:"GO:0010001"(glial cell differentiation)|go:"GO:0014069"(postsynaptic density)|go:"GO:0016198"(axon choice point recognition)|go:"GO:0030424"(axon)|go:"GO:0030425"(dendrite)|go:"GO:0030426"(growth cone)|go:"GO:0031103"(axon regeneration)|go:"GO:0031527"(filopodium membrane)|go:"GO:0032584"(growth cone membrane)|go:"GO:0035727"(lysophosphatidic acid binding)|go:"GO:0040008"(regulation of growth)|go:"GO:0042246"(tissue regeneration)|go:"GO:0043204"(perikaryon)|go:"GO:0045165"(cell fate commitment)|go:"GO:0051489"(regulation of filopodium assembly)|go:"GO:0071944"(cell periphery)|go:"GO:0098982"(GABA-ergic synapse)|go:"GO:0099150"(regulation of postsynaptic specialization assembly)|go:"GO:1901981"(phosphatidylinositol phosphate binding)|interpro:IPR000048(IQ calmodulin-binding region)|interpro:IPR001422("Neuromodulin (GAP-43)")|interpro:IPR017454("Neuromodulin (GAP-43), C-terminal")|interpro:IPR018243|interpro:IPR018947|interpro:IPR033137|mint:P07936|reactome:R-RNO-373760|refseq:NP_058891.1|rgd:62071	-	-	-	figure legend:F5D SF3|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10116(rat-brain-cortex)|taxid:10116(Rattus norvegicus brain cortex)	-	2020/10/30	2020/10/30	rogid:DtE+ZXAZKdCMvUW5K+jXQ5bH07M10116	rogid:PI3nUZq+f76xlzN4ebj0gW06/XI10116	rigid:Cy0T0pbtnKGsTfzkRYYZ3oRVEHw	false	-	-	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:Q5XIE8	uniprotkb:Q9QXY2	intact:EBI-15348306|ensembl:ENSRNOP00000023037	intact:EBI-1394088|uniprotkb:Q9QXY3|ensembl:ENSRNOP00000016070	psi-mi:itm2b_rat(display_long)|uniprotkb:Itm2b(gene name)|psi-mi:Itm2b(display_short)|uniprotkb:Immature BRI2(gene name synonym)|uniprotkb:Transmembrane protein BRI(gene name synonym)	psi-mi:srcn1_rat(display_long)|uniprotkb:Srcin1(gene name)|psi-mi:Srcin1(display_short)|uniprotkb:Snip(gene name synonym)|uniprotkb:p140Cap(gene name synonym)|uniprotkb:SNAP-25-interacting protein(gene name synonym)|uniprotkb:P140(gene name synonym)|uniprotkb:p130Cas-associated protein(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Martins et al. (2018)	imex:IM-28469|pubmed:29476059	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26439741|imex:IM-28469-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSRNOG00000016271(gene)|ensembl:ENSRNOT00000023037(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001540"(amyloid-beta binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0010008"(endosome membrane)|go:"GO:0030660"(Golgi-associated vesicle membrane)|go:"GO:0031301"(integral component of organelle membrane)|go:"GO:0042985"(negative regulation of amyloid precursor protein biosynthetic process)|interpro:IPR007084(BRICHOS)|interpro:IPR040145|mint:Q5XIE8|refseq:NP_001006964.1|rgd:620727	rgd:708439|refseq:NP_062251.1|ensembl:ENSRNOG00000011475(gene)|ensembl:ENSRNOT00000016070(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0006887"(exocytosis)|go:"GO:0007162"(negative regulation of cell adhesion)|go:"GO:0014069"(postsynaptic density)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0019901"(protein kinase binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030027"(lamellipodium)|go:"GO:0030175"(filopodium)|go:"GO:0030234"(enzyme regulator activity)|go:"GO:0030334"(regulation of cell migration)|go:"GO:0030424"(axon)|go:"GO:0030425"(dendrite)|go:"GO:0034446"(substrate adhesion-dependent cell spreading)|go:"GO:0043005"(neuron projection)|go:"GO:0043025"(neuronal cell body)|go:"GO:0045202"(synapse)|go:"GO:0050709"(negative regulation of protein secretion)|go:"GO:0061001"(regulation of dendritic spine morphogenesis)|go:"GO:0061098"(positive regulation of protein tyrosine kinase activity)|go:"GO:0061099"(negative regulation of protein tyrosine kinase activity)|go:"GO:0098793"(presynapse)|interpro:IPR022782|interpro:IPR026727|mint:Q9QXY2	-	-	-	figure legend:st1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10116(rat-brain-cortex)|taxid:10116(Rattus norvegicus brain cortex)	-	2020/10/30	2020/10/30	rogid:DtE+ZXAZKdCMvUW5K+jXQ5bH07M10116	rogid:vpuj/e+VqyDmaw6L6ah6jUJv5kI10116	rigid:3wclwrjZRvafcOruQOYnegkn54c	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q5XIE8	uniprotkb:Q5XI32	intact:EBI-15348306|ensembl:ENSRNOP00000023037	intact:EBI-2128068|ensembl:ENSRNOP00000010308	psi-mi:itm2b_rat(display_long)|uniprotkb:Itm2b(gene name)|psi-mi:Itm2b(display_short)|uniprotkb:Immature BRI2(gene name synonym)|uniprotkb:Transmembrane protein BRI(gene name synonym)	psi-mi:capzb_rat(display_long)|uniprotkb:Capzb(gene name)|psi-mi:Capzb(display_short)|uniprotkb:CapZ beta(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Martins et al. (2018)	imex:IM-28469|pubmed:29476059	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26439741|imex:IM-28469-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSRNOG00000016271(gene)|ensembl:ENSRNOT00000023037(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001540"(amyloid-beta binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0010008"(endosome membrane)|go:"GO:0030660"(Golgi-associated vesicle membrane)|go:"GO:0031301"(integral component of organelle membrane)|go:"GO:0042985"(negative regulation of amyloid precursor protein biosynthetic process)|interpro:IPR007084(BRICHOS)|interpro:IPR040145|mint:Q5XIE8|refseq:NP_001006964.1|rgd:620727	rgd:1359099|refseq:NP_001005903.1|ensembl:ENSRNOG00000007330(gene)|ensembl:ENSRNOT00000010308(transcript)|go:"GO:0000902"(cell morphogenesis)|go:"GO:0003779"(actin binding)|go:"GO:0005903"(brush border)|go:"GO:0007010"(cytoskeleton organization)|go:"GO:0008154"(actin polymerization or depolymerization)|go:"GO:0008290"(F-actin capping protein complex)|go:"GO:0010591"(regulation of lamellipodium assembly)|go:"GO:0014069"(postsynaptic density)|go:"GO:0016020"(membrane)|go:"GO:0022604"(regulation of cell morphogenesis)|go:"GO:0030017"(sarcomere)|go:"GO:0030027"(lamellipodium)|go:"GO:0030030"(cell projection organization)|go:"GO:0030032"(lamellipodium assembly)|go:"GO:0030863"(cortical cytoskeleton)|go:"GO:0032279"(asymmetric synapse)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043197"(dendritic spine)|go:"GO:0051015"(actin filament binding)|go:"GO:0051016"(barbed-end actin filament capping)|go:"GO:0051490"(negative regulation of filopodium assembly)|go:"GO:0071203"(WASH complex)|go:"GO:0097224"(sperm connecting piece)|go:"GO:0098685"(Schaffer collateral - CA1 synapse)|go:"GO:0098686"(hippocampal mossy fiber to CA3 synapse)|interpro:IPR001698(F-actin capping protein, beta subunit)|interpro:IPR019771|interpro:IPR037282|interpro:IPR042276|interpro:IPR043175|mint:Q5XI32|reactome:R-RNO-2132295|reactome:R-RNO-3371497|reactome:R-RNO-6807878|reactome:R-RNO-6811436|reactome:R-RNO-9013405|reactome:R-RNO-9035034|reactome:R-RNO-983231	-	-	-	figure legend:st1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10116(rat-brain-cortex)|taxid:10116(Rattus norvegicus brain cortex)	-	2020/10/30	2020/10/30	rogid:DtE+ZXAZKdCMvUW5K+jXQ5bH07M10116	rogid:48IQ1CJkjL9DdUW66uFlFKhRWxo10116	rigid:3wclwrjZRvafcOruQOYnegkn54c	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q5XIE8	uniprotkb:O35179	intact:EBI-15348306|ensembl:ENSRNOP00000023037	intact:EBI-1149197|ensembl:ENSRNOP00000008999	psi-mi:itm2b_rat(display_long)|uniprotkb:Itm2b(gene name)|psi-mi:Itm2b(display_short)|uniprotkb:Immature BRI2(gene name synonym)|uniprotkb:Transmembrane protein BRI(gene name synonym)	psi-mi:sh3g2_rat(display_long)|uniprotkb:Sh3gl2(gene name)|psi-mi:Sh3gl2(display_short)|uniprotkb:Endophilin-1(gene name synonym)|uniprotkb:SH3 domain-containing GRB2-like protein 2(gene name synonym)|uniprotkb:SH3 domain protein 2A(gene name synonym)|uniprotkb:SH3p4(gene name synonym)|uniprotkb:Sh3d2a(gene name synonym)|uniprotkb:Sh3p4(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Martins et al. (2018)	imex:IM-28469|pubmed:29476059	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26439741|imex:IM-28469-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSRNOG00000016271(gene)|ensembl:ENSRNOT00000023037(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001540"(amyloid-beta binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0010008"(endosome membrane)|go:"GO:0030660"(Golgi-associated vesicle membrane)|go:"GO:0031301"(integral component of organelle membrane)|go:"GO:0042985"(negative regulation of amyloid precursor protein biosynthetic process)|interpro:IPR007084(BRICHOS)|interpro:IPR040145|mint:Q5XIE8|refseq:NP_001006964.1|rgd:620727	refseq:NP_446387.1|rgd:620276|go:"GO:0001933"(negative regulation of protein phosphorylation)|go:"GO:0002090"(regulation of receptor internalization)|go:"GO:0005769"(early endosome)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008289"(lipid binding)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0016191"(synaptic vesicle uncoating)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030672"(synaptic vesicle membrane)|go:"GO:0031175"(neuron projection development)|go:"GO:0042802"(identical protein binding)|go:"GO:0043025"(neuronal cell body)|go:"GO:0045202"(synapse)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0048488"(synaptic vesicle endocytosis)|go:"GO:0060988"(lipid tube assembly)|go:"GO:0097441"(basal dendrite)|go:"GO:0097484"(dendrite extension)|go:"GO:0097749"(membrane tubulation)|go:"GO:0097753"(membrane bending)|go:"GO:0098684"(photoreceptor ribbon synapse)|go:"GO:0098685"(Schaffer collateral - CA1 synapse)|go:"GO:0098686"(hippocampal mossy fiber to CA3 synapse)|go:"GO:0098793"(presynapse)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099050"(vesicle scission)|go:"GO:0099523"(presynaptic cytosol)|go:"GO:1903527"(positive regulation of membrane tubulation)|go:"GO:1905604"(negative regulation of blood-brain barrier permeability)|go:"GO:1990416"(cellular response to brain-derived neurotrophic factor stimulus)|go:"GO:2000369"(regulation of clathrin-dependent endocytosis)|interpro:IPR001452(Src homology-3)|interpro:IPR004148(BAR)|interpro:IPR027267|interpro:IPR035824|interpro:IPR036028|mint:O35179|rcsb pdb:2C08|rcsb pdb:2KNB|rcsb pdb:3IQL|reactome:R-RNO-177504|reactome:R-RNO-182971|ensembl:ENSRNOT00000008999(transcript)|reactome:R-RNO-2132295|reactome:R-RNO-432720|reactome:R-RNO-432722|reactome:R-RNO-437239|reactome:R-RNO-6807004|reactome:R-RNO-8856825|reactome:R-RNO-8856828|ensembl:ENSRNOG00000006761(gene)	-	-	-	figure legend:st1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10116(rat-brain-cortex)|taxid:10116(Rattus norvegicus brain cortex)	-	2020/10/30	2020/10/30	rogid:DtE+ZXAZKdCMvUW5K+jXQ5bH07M10116	rogid:n3a31uT/o83hN0em2h7R7+p6pi010116	rigid:3wclwrjZRvafcOruQOYnegkn54c	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q5XIE8	uniprotkb:Q62910	intact:EBI-15348306|ensembl:ENSRNOP00000023037	intact:EBI-1149123|uniprotkb:O89092|uniprotkb:Q62911|uniprotkb:Q810Z8|ensembl:ENSRNOP00000060346	psi-mi:itm2b_rat(display_long)|uniprotkb:Itm2b(gene name)|psi-mi:Itm2b(display_short)|uniprotkb:Immature BRI2(gene name synonym)|uniprotkb:Transmembrane protein BRI(gene name synonym)	psi-mi:synj1_rat(display_long)|uniprotkb:Synj1(gene name)|psi-mi:Synj1(display_short)|uniprotkb:Synaptic inositol 1,4,5-trisphosphate 5-phosphatase 1(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Martins et al. (2018)	imex:IM-28469|pubmed:29476059	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26439741|imex:IM-28469-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSRNOG00000016271(gene)|ensembl:ENSRNOT00000023037(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001540"(amyloid-beta binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0010008"(endosome membrane)|go:"GO:0030660"(Golgi-associated vesicle membrane)|go:"GO:0031301"(integral component of organelle membrane)|go:"GO:0042985"(negative regulation of amyloid precursor protein biosynthetic process)|interpro:IPR007084(BRICHOS)|interpro:IPR040145|mint:Q5XIE8|refseq:NP_001006964.1|rgd:620727	rgd:69434|refseq:NP_445928.2|ensembl:ENSRNOG00000002051(gene)|ensembl:ENSRNOT00000065535(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0004438"(phosphatidylinositol-3-phosphatase activity)|go:"GO:0004439"(phosphatidylinositol-4,5-bisphosphate 5-phosphatase activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0006836"(neurotransmitter transport)|go:"GO:0007420"(brain development)|go:"GO:0007612"(learning)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0012506"(vesicle membrane)|go:"GO:0014015"(positive regulation of gliogenesis)|go:"GO:0016082"(synaptic vesicle priming)|go:"GO:0016191"(synaptic vesicle uncoating)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0030117"(membrane coat)|go:"GO:0030132"(clathrin coat of coated pit)|go:"GO:0032526"(response to retinoic acid)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034097"(response to cytokine)|go:"GO:0034595"(phosphatidylinositol phosphate 5-phosphatase activity)|go:"GO:0043005"(neuron projection)|go:"GO:0043195"(terminal bouton)|go:"GO:0043812"(phosphatidylinositol-4-phosphate phosphatase activity)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0046488"(phosphatidylinositol metabolic process)|go:"GO:0046855"(inositol phosphate dephosphorylation)|go:"GO:0046856"(phosphatidylinositol dephosphorylation)|go:"GO:0048260"(positive regulation of receptor-mediated endocytosis)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0048488"(synaptic vesicle endocytosis)|go:"GO:0048489"(synaptic vesicle transport)|go:"GO:0052658"(inositol-1,4,5-trisphosphate 5-phosphatase activity)|go:"GO:0097060"(synaptic membrane)|go:"GO:0098685"(Schaffer collateral - CA1 synapse)|go:"GO:0098688"(parallel fiber to Purkinje cell synapse)|go:"GO:0098793"(presynapse)|go:"GO:0098794"(postsynapse)|go:"GO:0098884"(postsynaptic neurotransmitter receptor internalization)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099149"(regulation of postsynaptic neurotransmitter receptor internalization)|go:"GO:1904980"(positive regulation of endosome organization)|go:"GO:1990175"(EH domain binding)|interpro:IPR000300(Inositol polyphosphate related phosphatase)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR002013(Synaptojanin, N-terminal)|interpro:IPR005135(Endonuclease/exonuclease/phosphatase)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR015047(Region of unknown function DUF1866)|interpro:IPR034971|interpro:IPR034972|interpro:IPR035979|interpro:IPR036691|mint:Q62910|reactome:R-RNO-1660499|reactome:R-RNO-1855183|reactome:R-RNO-1855204|reactome:R-RNO-8856828	-	-	-	figure legend:st1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10116(rat-brain-cortex)|taxid:10116(Rattus norvegicus brain cortex)	-	2020/10/30	2020/10/30	rogid:DtE+ZXAZKdCMvUW5K+jXQ5bH07M10116	rogid:EJnYHctzzxfhvA7evwx+c2HKuIE10116	rigid:3wclwrjZRvafcOruQOYnegkn54c	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q5XIE8	uniprotkb:P69682	intact:EBI-15348306|ensembl:ENSRNOP00000023037	intact:EBI-7592718|intact:MINT-5260811|uniprotkb:Q4QR67|ensembl:ENSRNOP00000013272	psi-mi:itm2b_rat(display_long)|uniprotkb:Itm2b(gene name)|psi-mi:Itm2b(display_short)|uniprotkb:Immature BRI2(gene name synonym)|uniprotkb:Transmembrane protein BRI(gene name synonym)	psi-mi:necp1_rat(display_long)|uniprotkb:Necap1(gene name)|psi-mi:Necap1(display_short)|uniprotkb:NECAP endocytosis-associated protein 1(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Martins et al. (2018)	imex:IM-28469|pubmed:29476059	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26439741|imex:IM-28469-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSRNOG00000016271(gene)|ensembl:ENSRNOT00000023037(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001540"(amyloid-beta binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0010008"(endosome membrane)|go:"GO:0030660"(Golgi-associated vesicle membrane)|go:"GO:0031301"(integral component of organelle membrane)|go:"GO:0042985"(negative regulation of amyloid precursor protein biosynthetic process)|interpro:IPR007084(BRICHOS)|interpro:IPR040145|mint:Q5XIE8|refseq:NP_001006964.1|rgd:620727	refseq:NP_001025090.1|rgd:1306053|ensembl:ENSRNOG00000009236(gene)|ensembl:ENSRNOT00000013272(transcript)|go:"GO:0005905"(clathrin-coated pit)|go:"GO:0006897"(endocytosis)|go:"GO:0015031"(protein transport)|go:"GO:0016192"(vesicle-mediated transport)|go:"GO:0030125"(clathrin vesicle coat)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR012466(Adaptin ear-binding coat-associated protein 1 NECAP-1)|mint:P69682|reactome:R-RNO-432722|reactome:R-RNO-8856825|reactome:R-RNO-8856828|dip:DIP-44064N	-	-	comment:mint|function:Involved in endocytosis	figure legend:st1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10116(rat-brain-cortex)|taxid:10116(Rattus norvegicus brain cortex)	-	2020/10/30	2020/10/30	rogid:DtE+ZXAZKdCMvUW5K+jXQ5bH07M10116	rogid:KwuJp3lG7BL4q4Fzy7YtThmdCso10116	rigid:3wclwrjZRvafcOruQOYnegkn54c	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q5XIE8	uniprotkb:P63025	intact:EBI-15348306|ensembl:ENSRNOP00000023037	intact:EBI-7705696|ensembl:ENSRNOP00000048364|intact:MINT-4139742|uniprotkb:Q64271	psi-mi:itm2b_rat(display_long)|uniprotkb:Itm2b(gene name)|psi-mi:Itm2b(display_short)|uniprotkb:Immature BRI2(gene name synonym)|uniprotkb:Transmembrane protein BRI(gene name synonym)	psi-mi:vamp3_rat(display_long)|uniprotkb:Vamp3(gene name)|psi-mi:Vamp3(display_short)|uniprotkb:Syb3(gene name synonym)|uniprotkb:Synaptobrevin-3(gene name synonym)|uniprotkb:Cellubrevin(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Martins et al. (2018)	imex:IM-28469|pubmed:29476059	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26439741|imex:IM-28469-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSRNOG00000016271(gene)|ensembl:ENSRNOT00000023037(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001540"(amyloid-beta binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0010008"(endosome membrane)|go:"GO:0030660"(Golgi-associated vesicle membrane)|go:"GO:0031301"(integral component of organelle membrane)|go:"GO:0042985"(negative regulation of amyloid precursor protein biosynthetic process)|interpro:IPR007084(BRICHOS)|interpro:IPR040145|mint:Q5XIE8|refseq:NP_001006964.1|rgd:620727	ensembl:ENSRNOG00000030055(gene)|ensembl:ENSRNOT00000051554(transcript)|go:"GO:0000149"(SNARE binding)|go:"GO:0001921"(positive regulation of receptor recycling)|go:"GO:0005484"(SNAP receptor activity)|go:"GO:0005769"(early endosome)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006906"(vesicle fusion)|go:"GO:0009986"(cell surface)|go:"GO:0016192"(vesicle-mediated transport)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0017075"(syntaxin-1 binding)|go:"GO:0017156"(calcium-ion regulated exocytosis)|go:"GO:0019905"(syntaxin binding)|go:"GO:0030136"(clathrin-coated vesicle)|go:"GO:0030141"(secretory granule)|go:"GO:0030285"(integral component of synaptic vesicle membrane)|go:"GO:0030665"(clathrin-coated vesicle membrane)|go:"GO:0031201"(SNARE complex)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0035493"(SNARE complex assembly)|go:"GO:0042147"(retrograde transport, endosome to Golgi)|go:"GO:0043001"(Golgi to plasma membrane protein transport)|go:"GO:0043005"(neuron projection)|go:"GO:0043229"(intracellular organelle)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0045335"(phagocytic vesicle)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0055037"(recycling endosome)|go:"GO:0065003"(protein-containing complex assembly)|go:"GO:0071346"(cellular response to interferon-gamma)|go:"GO:0097708"(intracellular vesicle)|go:"GO:1903531"(negative regulation of secretion by cell)|interpro:IPR001388(Synaptobrevin)|interpro:IPR016444(Synaptobrevin, metazoa/fungi)|interpro:IPR042855|mint:P63025|rcsb pdb:5KJ7|rcsb pdb:5KJ8|reactome:R-RNO-6811440|reactome:R-RNO-8856825|reactome:R-RNO-8856828|reactome:R-RNO-8980692|reactome:R-RNO-9013026|reactome:R-RNO-9013106|reactome:R-RNO-9013148|reactome:R-RNO-9013149|reactome:R-RNO-9013404|reactome:R-RNO-9013405|reactome:R-RNO-9013406|reactome:R-RNO-9013407|reactome:R-RNO-9013408|reactome:R-RNO-9013423|reactome:R-RNO-9035034|go:"GO:0034446"(substrate adhesion-dependent cell spreading)|refseq:NP_476438.1|rgd:61880	-	-	comment:mint|function:Trafficking protein from a constitutively recycling pathway	figure legend:st1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10116(rat-brain-cortex)|taxid:10116(Rattus norvegicus brain cortex)	-	2020/10/30	2020/10/30	rogid:DtE+ZXAZKdCMvUW5K+jXQ5bH07M10116	rogid:+bFr3sWwXWDPrsL8ZRrf+4CpLqo10116	rigid:3wclwrjZRvafcOruQOYnegkn54c	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q5XIE8	uniprotkb:Q9QYF3	intact:EBI-15348306|ensembl:ENSRNOP00000023037	intact:EBI-7622981|intact:MINT-7138773	psi-mi:itm2b_rat(display_long)|uniprotkb:Itm2b(gene name)|psi-mi:Itm2b(display_short)|uniprotkb:Immature BRI2(gene name synonym)|uniprotkb:Transmembrane protein BRI(gene name synonym)	psi-mi:myo5a_rat(display_long)|uniprotkb:Myo5a(gene name)|psi-mi:Myo5a(display_short)|uniprotkb:Dilute myosin heavy chain, non-muscle(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Martins et al. (2018)	imex:IM-28469|pubmed:29476059	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26439741|imex:IM-28469-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSRNOG00000016271(gene)|ensembl:ENSRNOT00000023037(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001540"(amyloid-beta binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0010008"(endosome membrane)|go:"GO:0030660"(Golgi-associated vesicle membrane)|go:"GO:0031301"(integral component of organelle membrane)|go:"GO:0042985"(negative regulation of amyloid precursor protein biosynthetic process)|interpro:IPR007084(BRICHOS)|interpro:IPR040145|mint:Q5XIE8|refseq:NP_001006964.1|rgd:620727	interpro:IPR004009(Myosin, N-terminal, SH3-like)|mint:Q9QYF3|interpro:IPR037988|interpro:IPR027417|rgd:3143|interpro:IPR001609(Myosin head, motor region)|interpro:IPR002710(Dilute)|refseq:NP_071514.1|interpro:IPR000048(IQ calmodulin-binding region)|go:"GO:0000146"(microfilament motor activity)|go:"GO:0000149"(SNARE binding)|go:"GO:0001726"(ruffle)|go:"GO:0001750"(photoreceptor outer segment)|go:"GO:0003774"(cytoskeletal motor activity)|go:"GO:0003779"(actin binding)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005790"(smooth endoplasmic reticulum)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0005882"(intermediate filament)|go:"GO:0006582"(melanin metabolic process)|go:"GO:0006887"(exocytosis)|go:"GO:0006892"(post-Golgi vesicle-mediated transport)|go:"GO:0007015"(actin filament organization)|go:"GO:0007268"(chemical synaptic transmission)|go:"GO:0007601"(visual perception)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0014046"(dopamine secretion)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0016020"(membrane)|go:"GO:0016192"(vesicle-mediated transport)|go:"GO:0016236"(macroautophagy)|go:"GO:0016459"(myosin complex)|go:"GO:0016461"(unconventional myosin complex)|go:"GO:0017075"(syntaxin-1 binding)|go:"GO:0017157"(regulation of exocytosis)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030048"(actin filament-based movement)|go:"GO:0030050"(vesicle transport along actin filament)|go:"GO:0030073"(insulin secretion)|go:"GO:0030141"(secretory granule)|go:"GO:0030318"(melanocyte differentiation)|go:"GO:0030424"(axon)|go:"GO:0030425"(dendrite)|go:"GO:0031267"(small GTPase binding)|go:"GO:0031585"(regulation of inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity)|go:"GO:0031982"(vesicle)|go:"GO:0031987"(locomotion involved in locomotory behavior)|go:"GO:0032252"(secretory granule localization)|go:"GO:0032400"(melanosome localization)|go:"GO:0032402"(melanosome transport)|go:"GO:0032433"(filopodium tip)|go:"GO:0032593"(insulin-responsive compartment)|go:"GO:0032869"(cellular response to insulin stimulus)|go:"GO:0035249"(synaptic transmission, glutamatergic)|go:"GO:0042417"(dopamine metabolic process)|go:"GO:0042438"(melanin biosynthetic process)|go:"GO:0042470"(melanosome)|go:"GO:0042476"(odontogenesis)|go:"GO:0042552"(myelination)|go:"GO:0042641"(actomyosin)|go:"GO:0042642"(actomyosin, myosin complex part)|go:"GO:0042759"(long-chain fatty acid biosynthetic process)|go:"GO:0042802"(identical protein binding)|go:"GO:0043005"(neuron projection)|go:"GO:0043008"(ATP-dependent protein binding)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043473"(pigmentation)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0048066"(developmental pigmentation)|go:"GO:0048306"(calcium-dependent protein binding)|go:"GO:0048820"(hair follicle maturation)|go:"GO:0050808"(synapse organization)|go:"GO:0050885"(neuromuscular process controlling balance)|go:"GO:0051015"(actin filament binding)|go:"GO:0051643"(endoplasmic reticulum localization)|go:"GO:0055037"(recycling endosome)|go:"GO:0065003"(protein-containing complex assembly)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0097718"(disordered domain specific binding)|go:"GO:0098685"(Schaffer collateral - CA1 synapse)|go:"GO:0098794"(postsynapse)|go:"GO:0098871"(postsynaptic actin cytoskeleton)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099089"(establishment of endoplasmic reticulum localization to postsynapse)|go:"GO:0099566"(regulation of postsynaptic cytosolic calcium ion concentration)|go:"GO:0099640"(axo-dendritic protein transport)|go:"GO:0150103"(reactive gliosis)|go:"GO:1900078"(positive regulation of cellular response to insulin stimulus)|go:"GO:1903078"(positive regulation of protein localization to plasma membrane)|go:"GO:1904754"(positive regulation of vascular associated smooth muscle cell migration)|go:"GO:1904960"(positive regulation of cytochrome-c oxidase activity)|go:"GO:1990904"(ribonucleoprotein complex)|reactome:R-RNO-2029482|interpro:IPR036103	-	-	comment:mint	figure legend:st1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10116(rat-brain-cortex)|taxid:10116(Rattus norvegicus brain cortex)	-	2020/10/30	2020/10/30	rogid:DtE+ZXAZKdCMvUW5K+jXQ5bH07M10116	rogid:ZQ1JIIcrUKmT1R7vXK9jJ+Ngw0w10116	rigid:3wclwrjZRvafcOruQOYnegkn54c	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q5XIE8	uniprotkb:G3V9R8	intact:EBI-15348306|ensembl:ENSRNOP00000023037	intact:EBI-7621160|uniprotkb:D4ACR0|uniprotkb:Q4V8K6|intact:MINT-7138494	psi-mi:itm2b_rat(display_long)|uniprotkb:Itm2b(gene name)|psi-mi:Itm2b(display_short)|uniprotkb:Immature BRI2(gene name synonym)|uniprotkb:Transmembrane protein BRI(gene name synonym)	psi-mi:hnrpc_rat(display_long)|uniprotkb:Hnrpc(gene name synonym)|uniprotkb:hnRNP core protein C(gene name synonym)|uniprotkb:Hnrnpc(gene name)|psi-mi:Hnrnpc(display_short)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Martins et al. (2018)	imex:IM-28469|pubmed:29476059	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26439741|imex:IM-28469-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSRNOG00000016271(gene)|ensembl:ENSRNOT00000023037(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001540"(amyloid-beta binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0010008"(endosome membrane)|go:"GO:0030660"(Golgi-associated vesicle membrane)|go:"GO:0031301"(integral component of organelle membrane)|go:"GO:0042985"(negative regulation of amyloid precursor protein biosynthetic process)|interpro:IPR007084(BRICHOS)|interpro:IPR040145|mint:Q5XIE8|refseq:NP_001006964.1|rgd:620727	interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|mint:G3V9R8|interpro:IPR000504(RNA recognition motif, RNP-1)|rgd:1309982|interpro:IPR017347(Heterogeneous nuclear ribonucleoprotein C, Raly)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0003730"(mRNA 3'-UTR binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0004857"(enzyme inhibitor activity)|go:"GO:0032211"(negative regulation of telomere maintenance via telomerase)|go:"GO:0032991"(protein-containing complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0005634"(nucleus)|go:"GO:0043021"(ribonucleoprotein complex binding)|go:"GO:0045120"(pronucleus)|go:"GO:0070034"(telomerase RNA binding)|go:"GO:0070935"(3'-UTR-mediated mRNA stabilization)|go:"GO:0071013"(catalytic step 2 spliceosome)|go:"GO:0090367"(negative regulation of mRNA modification)|go:"GO:1990247"(N6-methyladenosine-containing RNA binding)|go:"GO:0005681"(spliceosomal complex)|go:"GO:1990826"(nucleoplasmic periphery of the nuclear pore complex)|go:"GO:1990827"(deaminase binding)|reactome:R-RNO-4570464|go:"GO:0005697"(telomerase holoenzyme complex)|reactome:R-RNO-72163|reactome:R-RNO-9013418|reactome:R-RNO-9013422|go:"GO:0005829"(cytosol)|go:"GO:0008266"("poly(U) RNA binding")|go:"GO:0015629"(actin cytoskeleton)|interpro:IPR035979	-	-	comment:mint	figure legend:st1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10116(rat-brain-cortex)|taxid:10116(Rattus norvegicus brain cortex)	-	2020/10/30	2020/10/30	rogid:DtE+ZXAZKdCMvUW5K+jXQ5bH07M10116	rogid:cgiYueABuKLkNADHbWll/dynlLo10116	rigid:3wclwrjZRvafcOruQOYnegkn54c	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q5XIE8	uniprotkb:P59215	intact:EBI-15348306|ensembl:ENSRNOP00000023037	intact:EBI-8071125|intact:MINT-5028451|uniprotkb:P04900|intact:MINT-6380317|uniprotkb:P30033|ensembl:ENSRNOP00000026373	psi-mi:itm2b_rat(display_long)|uniprotkb:Itm2b(gene name)|psi-mi:Itm2b(display_short)|uniprotkb:Immature BRI2(gene name synonym)|uniprotkb:Transmembrane protein BRI(gene name synonym)	psi-mi:gnao_rat(display_long)|uniprotkb:Gnao1(gene name)|psi-mi:Gnao1(display_short)|uniprotkb:Gna0(gene name synonym)|uniprotkb:Gnao(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Martins et al. (2018)	imex:IM-28469|pubmed:29476059	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26439741|imex:IM-28469-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSRNOG00000016271(gene)|ensembl:ENSRNOT00000023037(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001540"(amyloid-beta binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0010008"(endosome membrane)|go:"GO:0030660"(Golgi-associated vesicle membrane)|go:"GO:0031301"(integral component of organelle membrane)|go:"GO:0042985"(negative regulation of amyloid precursor protein biosynthetic process)|interpro:IPR007084(BRICHOS)|interpro:IPR040145|mint:Q5XIE8|refseq:NP_001006964.1|rgd:620727	rgd:628732|refseq:NP_059023.1|dip:DIP-59090N|ensembl:ENSRNOG00000019482(gene)|ensembl:ENSRNOT00000026373(transcript)|go:"GO:0001664"(G protein-coupled receptor binding)|go:"GO:0003924"(GTPase activity)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005525"(GTP binding)|go:"GO:0005834"(heterotrimeric G-protein complex)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0007188"(adenylate cyclase-modulating G protein-coupled receptor signaling pathway)|go:"GO:0007212"(dopamine receptor signaling pathway)|go:"GO:0007568"(aging)|go:"GO:0007626"(locomotory behavior)|go:"GO:0008016"(regulation of heart contraction)|go:"GO:0009987"(cellular process)|go:"GO:0014070"(response to organic cyclic compound)|go:"GO:0016020"(membrane)|go:"GO:0019003"(GDP binding)|go:"GO:0030425"(dendrite)|go:"GO:0030900"(forebrain development)|go:"GO:0031175"(neuron projection development)|go:"GO:0031683"(G-protein beta/gamma-subunit complex binding)|go:"GO:0031821"(G protein-coupled serotonin receptor binding)|go:"GO:0031852"(mu-type opioid receptor binding)|go:"GO:0032794"(GTPase activating protein binding)|go:"GO:0034097"(response to cytokine)|go:"GO:0042475"(odontogenesis of dentin-containing tooth)|go:"GO:0042493"|go:"GO:0042542"(response to hydrogen peroxide)|go:"GO:0043005"(neuron projection)|go:"GO:0043209"(myelin sheath)|go:"GO:0043278"(response to morphine)|go:"GO:0043547"(positive regulation of GTPase activity)|go:"GO:0044297"(cell body)|go:"GO:0046872"(metal ion binding)|go:"GO:0051430"(corticotropin-releasing hormone receptor 1 binding)|go:"GO:0051926"(negative regulation of calcium ion transport)|interpro:IPR001019("Guanine nucleotide binding protein (G-protein), alpha subunit")|interpro:IPR001408(G-protein alpha subunit, group I)|interpro:IPR011025(G protein alpha subunit, helical insertion)|interpro:IPR027417|mint:P59215|reactome:R-RNO-4086398|go:"GO:0010243"(response to organonitrogen compound)	-	-	comment:mint|function:"Guanine nucleotide-binding proteins (G proteins) are involved as modulators or transducers in various transmembrane signaling systems. The G(o) protein function is not clear"|comment:homomint	figure legend:st1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10116(rat-brain-cortex)|taxid:10116(Rattus norvegicus brain cortex)	-	2020/10/30	2020/10/30	rogid:DtE+ZXAZKdCMvUW5K+jXQ5bH07M10116	rogid:LuKGAVyaFxWTp6ctQzokHhwyo3410116	rigid:3wclwrjZRvafcOruQOYnegkn54c	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q5XIE8	uniprotkb:P06687	intact:EBI-15348306|ensembl:ENSRNOP00000023037	intact:EBI-7617807|intact:MINT-7138201|uniprotkb:Q9Z1G6|uniprotkb:Q16732|ensembl:ENSRNOP00000027497	psi-mi:itm2b_rat(display_long)|uniprotkb:Itm2b(gene name)|psi-mi:Itm2b(display_short)|uniprotkb:Immature BRI2(gene name synonym)|uniprotkb:Transmembrane protein BRI(gene name synonym)	psi-mi:at1a3_rat(display_long)|uniprotkb:Atp1a3(gene name)|psi-mi:Atp1a3(display_short)|uniprotkb:"Na(+)/K(+) ATPase alpha(III) subunit"(gene name synonym)|uniprotkb:Sodium pump subunit alpha-3(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Martins et al. (2018)	imex:IM-28469|pubmed:29476059	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26439741|imex:IM-28469-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSRNOG00000016271(gene)|ensembl:ENSRNOT00000023037(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001540"(amyloid-beta binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0010008"(endosome membrane)|go:"GO:0030660"(Golgi-associated vesicle membrane)|go:"GO:0031301"(integral component of organelle membrane)|go:"GO:0042985"(negative regulation of amyloid precursor protein biosynthetic process)|interpro:IPR007084(BRICHOS)|interpro:IPR040145|mint:Q5XIE8|refseq:NP_001006964.1|rgd:620727	rgd:2169|refseq:NP_036638.1|ensembl:ENSRNOG00000020263(gene)|ensembl:ENSRNOT00000027497(transcript)|go:"GO:0001540"(amyloid-beta binding)|go:"GO:0001917"(photoreceptor inner segment)|go:"GO:0005391"("P-type sodium:potassium-exchanging transporter activity")|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005890"("sodium:potassium-exchanging ATPase complex")|go:"GO:0006813"(potassium ion transport)|go:"GO:0006814"(sodium ion transport)|go:"GO:0006883"(cellular sodium ion homeostasis)|go:"GO:0007613"(memory)|go:"GO:0008344"(adult locomotory behavior)|go:"GO:0008542"(visual learning)|go:"GO:0016020"(membrane)|go:"GO:0021987"(cerebral cortex development)|go:"GO:0030007"(cellular potassium ion homeostasis)|go:"GO:0030424"(axon)|go:"GO:0031090"(organelle membrane)|go:"GO:0031748"(D1 dopamine receptor binding)|go:"GO:0035235"(ionotropic glutamate receptor signaling pathway)|go:"GO:0036376"(sodium ion export across plasma membrane)|go:"GO:0042383"(sarcolemma)|go:"GO:0042493"|go:"GO:0043025"(neuronal cell body)|go:"GO:0043209"(myelin sheath)|go:"GO:0043395"(heparan sulfate proteoglycan binding)|go:"GO:0044305"(calyx of Held)|go:"GO:0044326"(dendritic spine neck)|go:"GO:0044327"(dendritic spine head)|go:"GO:0045202"(synapse)|go:"GO:0046872"(metal ion binding)|go:"GO:0051087"(chaperone binding)|go:"GO:0060048"(cardiac muscle contraction)|go:"GO:0071300"(cellular response to retinoic acid)|go:"GO:0086036"(regulation of cardiac muscle cell membrane potential)|go:"GO:0086037"("P-type sodium:potassium-exchanging transporter activity involved in regulation of cardiac muscle cell membrane potential")|go:"GO:0097067"(cellular response to thyroid hormone stimulus)|go:"GO:0098794"(postsynapse)|go:"GO:0098984"(neuron to neuron synapse)|go:"GO:0099056"(integral component of presynaptic membrane)|go:"GO:0099520"(ion antiporter activity involved in regulation of presynaptic membrane potential)|go:"GO:1902600"(proton transmembrane transport)|go:"GO:1904646"(cellular response to amyloid-beta)|go:"GO:1990535"(neuron projection maintenance)|go:"GO:1990573"(potassium ion import across plasma membrane)|interpro:IPR001757(ATPase, P-type, K/Mg/Cd/Cu/Zn/Na/Ca/Na/H-transporter)|interpro:IPR004014(ATPase, P-type cation-transporter, N-terminal)|interpro:IPR005775(ATPase, P-type cation exchange, alpha subunit, eukaryotic)|interpro:IPR006068(ATPase, P-type cation-transporter, C-terminal)|interpro:IPR008250(E1-E2 ATPase-associated region)|interpro:IPR018303|interpro:IPR023214|interpro:IPR023298|interpro:IPR023299|interpro:IPR036412|interpro:IPR044492|mint:P06687|reactome:R-RNO-5578775|reactome:R-RNO-936837|go:"GO:0005886"(plasma membrane)	-	-	comment:mint	figure legend:st1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10116(rat-brain-cortex)|taxid:10116(Rattus norvegicus brain cortex)	-	2020/10/30	2020/10/30	rogid:DtE+ZXAZKdCMvUW5K+jXQ5bH07M10116	rogid:1sz4qkpfVGTvDfvmBVIE3wsH2Rs10116	rigid:3wclwrjZRvafcOruQOYnegkn54c	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q5XIE8	uniprotkb:P63329	intact:EBI-15348306|ensembl:ENSRNOP00000023037	intact:EBI-7022944|ensembl:ENSRNOP00000049674|uniprotkb:P20652|uniprotkb:Q9Z1I5|uniprotkb:Q6LDJ8|uniprotkb:Q9WUV7|uniprotkb:P12816|intact:MINT-4106043	psi-mi:itm2b_rat(display_long)|uniprotkb:Itm2b(gene name)|psi-mi:Itm2b(display_short)|uniprotkb:Immature BRI2(gene name synonym)|uniprotkb:Transmembrane protein BRI(gene name synonym)	psi-mi:pp2ba_rat(display_long)|uniprotkb:Ppp3ca(gene name)|psi-mi:Ppp3ca(display_short)|uniprotkb:Calna(gene name synonym)|uniprotkb:Calmodulin-dependent calcineurin A subunit alpha isoform(gene name synonym)|uniprotkb:CAM-PRP catalytic subunit(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Martins et al. (2018)	imex:IM-28469|pubmed:29476059	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26439741|imex:IM-28469-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSRNOG00000016271(gene)|ensembl:ENSRNOT00000023037(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001540"(amyloid-beta binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0010008"(endosome membrane)|go:"GO:0030660"(Golgi-associated vesicle membrane)|go:"GO:0031301"(integral component of organelle membrane)|go:"GO:0042985"(negative regulation of amyloid precursor protein biosynthetic process)|interpro:IPR007084(BRICHOS)|interpro:IPR040145|mint:Q5XIE8|refseq:NP_001006964.1|rgd:620727	refseq:XP_006233425.1|ensembl:ENSRNOG00000009882(gene)|ensembl:ENSRNOT00000047975(transcript)|go:"GO:0000082"(G1/S transition of mitotic cell cycle)|go:"GO:0001975"(response to amphetamine)|go:"GO:0004721"(phosphoprotein phosphatase activity)|go:"GO:0004722"(protein serine/threonine phosphatase activity)|go:"GO:0004723"(calcium-dependent protein serine/threonine phosphatase activity)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005955"(calcineurin complex)|go:"GO:0006470"(protein dephosphorylation)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0006816"(calcium ion transport)|go:"GO:0007420"(brain development)|go:"GO:0007568"(aging)|go:"GO:0009898"(cytoplasmic side of plasma membrane)|go:"GO:0010613"(positive regulation of cardiac muscle hypertrophy)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0014883"(transition between fast and slow fiber)|go:"GO:0014898"(cardiac muscle hypertrophy in response to stress)|go:"GO:0016018"(cyclosporin A binding)|go:"GO:0016311"(dephosphorylation)|go:"GO:0019722"(calcium-mediated signaling)|go:"GO:0019899"(enzyme binding)|go:"GO:0030018"(Z disc)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0033173"(calcineurin-NFAT signaling cascade)|go:"GO:0033192"(calmodulin-dependent protein phosphatase activity)|go:"GO:0033555"(multicellular organismal response to stress)|go:"GO:0035562"(negative regulation of chromatin binding)|go:"GO:0042383"(sarcolemma)|go:"GO:0043197"(dendritic spine)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045202"(synapse)|go:"GO:0045785"(positive regulation of cell adhesion)|go:"GO:0045807"(positive regulation of endocytosis)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0045955"(negative regulation of calcium ion-dependent exocytosis)|go:"GO:0046676"(negative regulation of insulin secretion)|go:"GO:0046872"(metal ion binding)|go:"GO:0046983"(protein dimerization activity)|go:"GO:0048741"(skeletal muscle fiber development)|go:"GO:0050774"(negative regulation of dendrite morphogenesis)|go:"GO:0050804"(modulation of chemical synaptic transmission)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0051117"(ATPase binding)|go:"GO:0051592"(response to calcium ion)|go:"GO:0060079"(excitatory postsynaptic potential)|go:"GO:0070262"(peptidyl-serine dephosphorylation)|go:"GO:0071333"(cellular response to glucose stimulus)|go:"GO:0097720"(calcineurin-mediated signaling)|go:"GO:0098685"(Schaffer collateral - CA1 synapse)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099170"(postsynaptic modulation of chemical synaptic transmission)|go:"GO:0106306"|go:"GO:0106307"|go:"GO:1903244"(positive regulation of cardiac muscle hypertrophy in response to stress)|go:"GO:1903799"(negative regulation of production of miRNAs involved in gene silencing by miRNA)|go:"GO:1905205"(positive regulation of connective tissue replacement)|interpro:IPR004843(Metallophosphoesterase)|interpro:IPR006186("Serine/threonine-specific protein phosphatase and bis(5-nucleosyl)-tetraphosphatase")|interpro:IPR029052|interpro:IPR041751|interpro:IPR043360|mint:P63329|rcsb pdb:4IL1|reactome:R-RNO-2025928|reactome:R-RNO-2871809|reactome:R-RNO-4086398|reactome:R-RNO-5607763|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|refseq:NP_058737.1|rgd:3382	-	-	comment:mint|function:Calcium-dependent, calmodulin-stimulated protein phosphatase. This subunit may have a role in the calmodulin activation of calcineurin. Dephosphorylates HSPB1. May also dephosphorylate and activate SSH1	figure legend:st1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10116(rat-brain-cortex)|taxid:10116(Rattus norvegicus brain cortex)	-	2020/10/30	2020/10/30	rogid:DtE+ZXAZKdCMvUW5K+jXQ5bH07M10116	rogid:98yAyDGZZxKYOv22ejceyfJbvao10116	rigid:3wclwrjZRvafcOruQOYnegkn54c	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q5XIE8	uniprotkb:O35413	intact:EBI-15348306|ensembl:ENSRNOP00000023037	intact:EBI-7458031|uniprotkb:Q923T8|intact:MINT-1216268	psi-mi:itm2b_rat(display_long)|uniprotkb:Itm2b(gene name)|psi-mi:Itm2b(display_short)|uniprotkb:Immature BRI2(gene name synonym)|uniprotkb:Transmembrane protein BRI(gene name synonym)	psi-mi:srbs2_rat(display_long)|uniprotkb:Arg-binding protein 2(gene name synonym)|uniprotkb:Argbp2(gene name synonym)|uniprotkb:Arg/Abl-interacting protein 2(gene name synonym)|uniprotkb:Neural ArgBP2(gene name synonym)|uniprotkb:Sorbin(gene name synonym)|uniprotkb:Sorbs2(gene name)|psi-mi:Sorbs2(display_short)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Martins et al. (2018)	imex:IM-28469|pubmed:29476059	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26439741|imex:IM-28469-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSRNOG00000016271(gene)|ensembl:ENSRNOT00000023037(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001540"(amyloid-beta binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0010008"(endosome membrane)|go:"GO:0030660"(Golgi-associated vesicle membrane)|go:"GO:0031301"(integral component of organelle membrane)|go:"GO:0042985"(negative regulation of amyloid precursor protein biosynthetic process)|interpro:IPR007084(BRICHOS)|interpro:IPR040145|mint:Q5XIE8|refseq:NP_001006964.1|rgd:620727	mint:O35413|interpro:IPR028506|interpro:IPR036028|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR001452(Src homology-3)|interpro:IPR003127(Sorbin-like)|refseq:NP_446222.1|rgd:620061|go:"GO:0005886"(plasma membrane)|go:"GO:0005925"(focal adhesion)|go:"GO:0007015"(actin filament organization)|go:"GO:0007219"(Notch signaling pathway)|go:"GO:0014069"(postsynaptic density)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030027"(lamellipodium)|go:"GO:0030425"(dendrite)|go:"GO:0043025"(neuronal cell body)|go:"GO:0045202"(synapse)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0061049"(cell growth involved in cardiac muscle cell development)|go:"GO:0095500"(acetylcholine receptor signaling pathway)|go:"GO:1904393"(regulation of skeletal muscle acetylcholine-gated channel clustering)	-	-	comment:mint	figure legend:st1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10116(rat-brain-cortex)|taxid:10116(Rattus norvegicus brain cortex)	-	2020/10/30	2020/10/30	rogid:DtE+ZXAZKdCMvUW5K+jXQ5bH07M10116	rogid:PPlOlF5Zo+yeGF3p4kxWBpCtE3w10116	rigid:3wclwrjZRvafcOruQOYnegkn54c	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q5XIE8	uniprotkb:P48768	intact:EBI-15348306|ensembl:ENSRNOP00000023037	intact:EBI-7400734|intact:MINT-8290508	psi-mi:itm2b_rat(display_long)|uniprotkb:Itm2b(gene name)|psi-mi:Itm2b(display_short)|uniprotkb:Immature BRI2(gene name synonym)|uniprotkb:Transmembrane protein BRI(gene name synonym)	psi-mi:nac2_rat(display_long)|uniprotkb:Slc8a2(gene name)|psi-mi:Slc8a2(display_short)|uniprotkb:"Na(+)/Ca(2+)-exchange protein 2"(gene name synonym)|uniprotkb:Ncx2(gene name synonym)|uniprotkb:Solute carrier family 8 member 2(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Martins et al. (2018)	imex:IM-28469|pubmed:29476059	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26439741|imex:IM-28469-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSRNOG00000016271(gene)|ensembl:ENSRNOT00000023037(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001540"(amyloid-beta binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0010008"(endosome membrane)|go:"GO:0030660"(Golgi-associated vesicle membrane)|go:"GO:0031301"(integral component of organelle membrane)|go:"GO:0042985"(negative regulation of amyloid precursor protein biosynthetic process)|interpro:IPR007084(BRICHOS)|interpro:IPR040145|mint:Q5XIE8|refseq:NP_001006964.1|rgd:620727	mint:P48768|interpro:IPR032452|interpro:IPR004836(Sodium/calcium exchanger protein)|rgd:620194|interpro:IPR004837(Sodium/calcium exchanger membrane region)|refseq:NP_511174.1|interpro:IPR003644(Na-Ca exchanger/integrin-beta4)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043197"(dendritic spine)|go:"GO:0043204"(perikaryon)|go:"GO:0043679"(axon terminus)|go:"GO:0045202"(synapse)|go:"GO:0042995"(cell projection)|go:"GO:0046872"(metal ion binding)|go:"GO:0048172"(regulation of short-term neuronal synaptic plasticity)|go:"GO:0050808"(synapse organization)|go:"GO:0050890"(cognition)|go:"GO:0051480"(regulation of cytosolic calcium ion concentration)|go:"GO:0060291"(long-term synaptic potentiation)|go:"GO:0060402"(calcium ion transport into cytosol)|go:"GO:0070050"(neuron cellular homeostasis)|go:"GO:0070588"(calcium ion transmembrane transport)|go:"GO:0071902"(positive regulation of protein serine/threonine kinase activity)|go:"GO:0098703"(calcium ion import across plasma membrane)|go:"GO:0098793"(presynapse)|go:"GO:0098794"(postsynapse)|go:"GO:0098815"(modulation of excitatory postsynaptic potential)|go:"GO:0099055"(integral component of postsynaptic membrane)|go:"GO:0099608"(regulation of action potential firing pattern)|go:"GO:0106056"(regulation of calcineurin-mediated signaling)|go:"GO:1905060"("calcium:cation antiporter activity involved in regulation of postsynaptic cytosolic calcium ion concentration")|go:"GO:1990034"(calcium ion export across plasma membrane)|reactome:R-RNO-418359|reactome:R-RNO-425561|reactome:R-RNO-5578775|go:"GO:0002931"(response to ischemia)|go:"GO:0005432"("calcium:sodium antiporter activity")|go:"GO:0005516"(calmodulin binding)|go:"GO:0005739"(mitochondrion)|go:"GO:0005874"(microtubule)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006814"(sodium ion transport)|go:"GO:0006874"(cellular calcium ion homeostasis)|go:"GO:0007154"(cell communication)|go:"GO:0007611"(learning or memory)|go:"GO:0007612"(learning)|go:"GO:0007613"(memory)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0014069"(postsynaptic density)|go:"GO:0015081"(sodium ion transmembrane transporter activity)|go:"GO:0015085"(calcium ion transmembrane transporter activity)|go:"GO:0015491"("cation:cation antiporter activity")|go:"GO:0016020"(membrane)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0021537"(telencephalon development)|go:"GO:0030001"(metal ion transport)|go:"GO:0030424"(axon)|go:"GO:0030425"(dendrite)|go:"GO:0032592"(integral component of mitochondrial membrane)|go:"GO:0033280"(response to vitamin D)|go:"GO:0035725"(sodium ion transmembrane transport)|go:"GO:0042383"(sarcolemma)|interpro:IPR038081	-	-	comment:mint	figure legend:st1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10116(rat-brain-cortex)|taxid:10116(Rattus norvegicus brain cortex)	-	2020/10/30	2020/10/30	rogid:DtE+ZXAZKdCMvUW5K+jXQ5bH07M10116	rogid:RnsoytLMi2xvjb5EnxouRUUwR1410116	rigid:3wclwrjZRvafcOruQOYnegkn54c	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q5XIE8	uniprotkb:Q4QQT4	intact:EBI-15348306|ensembl:ENSRNOP00000023037	intact:EBI-7152576|ensembl:ENSRNOP00000059428|intact:UNK-5426275	psi-mi:itm2b_rat(display_long)|uniprotkb:Itm2b(gene name)|psi-mi:Itm2b(display_short)|uniprotkb:Immature BRI2(gene name synonym)|uniprotkb:Transmembrane protein BRI(gene name synonym)	psi-mi:2aab_rat(display_long)|uniprotkb:PP2A subunit A isoform R1-beta(gene name synonym)|uniprotkb:PP2A subunit A isoform PR65-beta(gene name synonym)|uniprotkb:Ppp2r1b(gene name)|psi-mi:Ppp2r1b(display_short)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Martins et al. (2018)	imex:IM-28469|pubmed:29476059	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26439741|imex:IM-28469-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSRNOG00000016271(gene)|ensembl:ENSRNOT00000023037(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001540"(amyloid-beta binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0010008"(endosome membrane)|go:"GO:0030660"(Golgi-associated vesicle membrane)|go:"GO:0031301"(integral component of organelle membrane)|go:"GO:0042985"(negative regulation of amyloid precursor protein biosynthetic process)|interpro:IPR007084(BRICHOS)|interpro:IPR040145|mint:Q5XIE8|refseq:NP_001006964.1|rgd:620727	ensembl:ENSRNOG00000010922(gene)|ensembl:ENSRNOT00000064290(transcript)|go:"GO:0000159"(protein phosphatase type 2A complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0006470"(protein dephosphorylation)|go:"GO:0019888"(protein phosphatase regulator activity)|go:"GO:0045121"(membrane raft)|go:"GO:0045202"(synapse)|go:"GO:0060561"(apoptotic process involved in morphogenesis)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:2001241"(positive regulation of extrinsic apoptotic signaling pathway in absence of ligand)|interpro:IPR000357(HEAT)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR021133|mint:Q4QQT4|reactome:R-RNO-113501|reactome:R-RNO-141444|reactome:R-RNO-180024|reactome:R-RNO-195253|reactome:R-RNO-196299|reactome:R-RNO-198753|reactome:R-RNO-202670|reactome:R-RNO-2467813|reactome:R-RNO-2500257|reactome:R-RNO-389513|reactome:R-RNO-4641262|reactome:R-RNO-5663220|reactome:R-RNO-5673000|reactome:R-RNO-5675221|reactome:R-RNO-6804757|reactome:R-RNO-6811558|reactome:R-RNO-68877|reactome:R-RNO-69231|reactome:R-RNO-69273|reactome:R-RNO-9648025|rgd:1304764|refseq:NP_001020589.1	-	-	function:The PR65 subunit of protein phosphatase 2A serves as a scaffolding molecule to coordinate the assembly of the catalytic subunit and a variable regulatory B subunit|comment:mint	figure legend:st1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10116(rat-brain-cortex)|taxid:10116(Rattus norvegicus brain cortex)	-	2020/10/30	2020/10/30	rogid:DtE+ZXAZKdCMvUW5K+jXQ5bH07M10116	rogid:ayq8HKJeRrRHxa93NOIiP4zoXA810116	rigid:3wclwrjZRvafcOruQOYnegkn54c	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q5XIE8	uniprotkb:Q64542	intact:EBI-15348306|ensembl:ENSRNOP00000023037	intact:EBI-8582022|ensembl:ENSRNOP00000004078|uniprotkb:Q63445|uniprotkb:Q63127|uniprotkb:Q64545|intact:MINT-4997403|uniprotkb:Q64543|uniprotkb:Q64544	psi-mi:itm2b_rat(display_long)|uniprotkb:Itm2b(gene name)|psi-mi:Itm2b(display_short)|uniprotkb:Immature BRI2(gene name synonym)|uniprotkb:Transmembrane protein BRI(gene name synonym)	psi-mi:at2b4_rat(display_long)|uniprotkb:Plasma membrane calcium ATPase isoform 4(gene name synonym)|uniprotkb:Plasma membrane calcium pump isoform 4(gene name synonym)|uniprotkb:Atp2b4(gene name)|psi-mi:Atp2b4(display_short)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Martins et al. (2018)	imex:IM-28469|pubmed:29476059	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26439741|imex:IM-28469-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSRNOG00000016271(gene)|ensembl:ENSRNOT00000023037(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001540"(amyloid-beta binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0010008"(endosome membrane)|go:"GO:0030660"(Golgi-associated vesicle membrane)|go:"GO:0031301"(integral component of organelle membrane)|go:"GO:0042985"(negative regulation of amyloid precursor protein biosynthetic process)|interpro:IPR007084(BRICHOS)|interpro:IPR040145|mint:Q5XIE8|refseq:NP_001006964.1|rgd:620727	ensembl:ENSRNOG00000003031(gene)|ensembl:ENSRNOT00000004078(transcript)|go:"GO:0003407"(neural retina development)|go:"GO:0005388"(P-type calcium transporter activity)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005524"(ATP binding)|refseq:XP_008767668.1|refseq:XP_008767669.1|refseq:XP_008767670.1|refseq:XP_008767671.1|refseq:XP_008767672.1|go:"GO:0014832"(urinary bladder smooth muscle contraction)|go:"GO:0015085"(calcium ion transmembrane transporter activity)|go:"GO:0016020"(membrane)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016525"(negative regulation of angiogenesis)|go:"GO:0019829"(ATPase-coupled cation transmembrane transporter activity)|go:"GO:0019901"(protein kinase binding)|go:"GO:0021766"(hippocampus development)|go:"GO:0030018"(Z disc)|go:"GO:0030165"(PDZ domain binding)|go:"GO:0030315"(T-tubule)|go:"GO:0030317"(flagellated sperm motility)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0030346"(protein phosphatase 2B binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033138"(positive regulation of peptidyl-serine phosphorylation)|go:"GO:0036126"(sperm flagellum)|go:"GO:0036487"(nitric-oxide synthase inhibitor activity)|go:"GO:0042383"(sarcolemma)|go:"GO:0043005"(neuron projection)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0043537"(negative regulation of blood vessel endothelial cell migration)|go:"GO:0045019"(negative regulation of nitric oxide biosynthetic process)|go:"GO:0046872"(metal ion binding)|go:"GO:0048306"(calcium-dependent protein binding)|go:"GO:0050998"(nitric-oxide synthase binding)|go:"GO:0051001"(negative regulation of nitric-oxide synthase activity)|go:"GO:0051480"(regulation of cytosolic calcium ion concentration)|go:"GO:0051599"(response to hydrostatic pressure)|go:"GO:0070588"(calcium ion transmembrane transport)|go:"GO:0070885"(negative regulation of calcineurin-NFAT signaling cascade)|go:"GO:0071872"(cellular response to epinephrine stimulus)|go:"GO:0097110"(scaffold protein binding)|go:"GO:0097228"(sperm principal piece)|go:"GO:0098736"(negative regulation of the force of heart contraction)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099059"(integral component of presynaptic active zone membrane)|go:"GO:0140199"(negative regulation of adenylate cyclase-activating adrenergic receptor signaling pathway involved in heart process)|go:"GO:1900082"(negative regulation of arginine catabolic process)|go:"GO:1901660"(calcium ion export)|go:"GO:1902548"(negative regulation of cellular response to vascular endothelial growth factor stimulus)|go:"GO:1902806"(regulation of cell cycle G1/S phase transition)|go:"GO:1903078"(positive regulation of protein localization to plasma membrane)|go:"GO:1903243"(negative regulation of cardiac muscle hypertrophy in response to stress)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:1903249"(negative regulation of citrulline biosynthetic process)|go:"GO:1905145"(cellular response to acetylcholine)|go:"GO:0006816"(calcium ion transport)|go:"GO:2000481"(positive regulation of cAMP-dependent protein kinase activity)|interpro:IPR001757(ATPase, P-type, K/Mg/Cd/Cu/Zn/Na/Ca/Na/H-transporter)|go:"GO:0006874"(cellular calcium ion homeostasis)|go:"GO:0007283"(spermatogenesis)|interpro:IPR004014(ATPase, P-type cation-transporter, N-terminal)|interpro:IPR006068(ATPase, P-type cation-transporter, C-terminal)|interpro:IPR006408(Calcium-translocating P-type ATPase, PMCA-type)|interpro:IPR008250(E1-E2 ATPase-associated region)|interpro:IPR018303|interpro:IPR022141|interpro:IPR023214|interpro:IPR023298|interpro:IPR023299|interpro:IPR036412|interpro:IPR044492|mint:Q64542|reactome:R-RNO-418359|reactome:R-RNO-5578775|reactome:R-RNO-936837|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0010751"(negative regulation of nitric oxide mediated signal transduction)|refseq:NP_001005871.1|rgd:621305	-	-	comment:mint|function:This magnesium-dependent enzyme catalyzes the hydrolysis of ATP coupled with the transport of calcium out of the cell	figure legend:st1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10116(rat-brain-cortex)|taxid:10116(Rattus norvegicus brain cortex)	-	2020/10/30	2020/10/30	rogid:DtE+ZXAZKdCMvUW5K+jXQ5bH07M10116	rogid:/HKft45YmH/TCae9h6Dpjihn74o10116	rigid:3wclwrjZRvafcOruQOYnegkn54c	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q5XIE8	uniprotkb:O35867	intact:EBI-15348306|ensembl:ENSRNOP00000023037	intact:EBI-7092421|ensembl:ENSRNOP00000011756|intact:MINT-107263	psi-mi:itm2b_rat(display_long)|uniprotkb:Itm2b(gene name)|psi-mi:Itm2b(display_short)|uniprotkb:Immature BRI2(gene name synonym)|uniprotkb:Transmembrane protein BRI(gene name synonym)	psi-mi:neb1_rat(display_long)|uniprotkb:Ppp1r9a(gene name)|psi-mi:Ppp1r9a(display_short)|uniprotkb:Neurabin-I(gene name synonym)|uniprotkb:p180(gene name synonym)|uniprotkb:PP1bp175(gene name synonym)|uniprotkb:Neural tissue-specific F-actin-binding protein I(gene name synonym)|uniprotkb:Protein phosphatase 1 regulatory subunit 9A(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Martins et al. (2018)	imex:IM-28469|pubmed:29476059	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26439741|imex:IM-28469-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSRNOG00000016271(gene)|ensembl:ENSRNOT00000023037(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001540"(amyloid-beta binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0010008"(endosome membrane)|go:"GO:0030660"(Golgi-associated vesicle membrane)|go:"GO:0031301"(integral component of organelle membrane)|go:"GO:0042985"(negative regulation of amyloid precursor protein biosynthetic process)|interpro:IPR007084(BRICHOS)|interpro:IPR040145|mint:Q5XIE8|refseq:NP_001006964.1|rgd:620727	go:"GO:1900454"(positive regulation of long-term synaptic depression)|go:"GO:1904049"(negative regulation of spontaneous neurotransmitter secretion)|go:"GO:1990761"(growth cone lamellipodium)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR001660(Sterile alpha motif SAM)|interpro:IPR013761(Sterile alpha motif-type)|interpro:IPR029994|interpro:IPR036034|interpro:IPR040645|interpro:IPR043446|mint:O35867|rcsb pdb:2FN5|rcsb pdb:2GLE|rcsb pdb:3HVQ|go:"GO:1900272"(negative regulation of long-term synaptic potentiation)|ensembl:ENSRNOG00000008869(gene)|ensembl:ENSRNOT00000011756(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0007015"(actin filament organization)|go:"GO:0007568"(aging)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008157"(protein phosphatase 1 binding)|go:"GO:0010976"(positive regulation of neuron projection development)|go:"GO:0014069"(postsynaptic density)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0019722"(calcium-mediated signaling)|go:"GO:0019901"(protein kinase binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030027"(lamellipodium)|go:"GO:0030175"(filopodium)|go:"GO:0030425"(dendrite)|go:"GO:0030426"(growth cone)|go:"GO:0030833"(regulation of actin filament polymerization)|go:"GO:0030864"(cortical actin cytoskeleton)|go:"GO:0031175"(neuron projection development)|go:"GO:0031594"(neuromuscular junction)|go:"GO:0042802"(identical protein binding)|go:"GO:0043005"(neuron projection)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043197"(dendritic spine)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0044326"(dendritic spine neck)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045202"(synapse)|go:"GO:0045860"(positive regulation of protein kinase activity)|go:"GO:0048666"(neuron development)|go:"GO:0050804"(modulation of chemical synaptic transmission)|go:"GO:0051015"(actin filament binding)|go:"GO:0051020"(GTPase binding)|go:"GO:0051489"(regulation of filopodium assembly)|go:"GO:0051497"(negative regulation of stress fiber assembly)|go:"GO:0051823"(regulation of synapse structural plasticity)|go:"GO:0051963"(regulation of synapse assembly)|go:"GO:0060079"(excitatory postsynaptic potential)|go:"GO:0060999"(positive regulation of dendritic spine development)|go:"GO:0061001"(regulation of dendritic spine morphogenesis)|go:"GO:0097237"(cellular response to toxic substance)|go:"GO:0098871"(postsynaptic actin cytoskeleton)|go:"GO:0098974"(postsynaptic actin cytoskeleton organization)|go:"GO:0098978"(glutamatergic synapse)|refseq:NP_445925.1|rgd:632280|dip:DIP-40850N	-	-	comment:mint|function:"Binds to actin filaments (F-actin) and shows cross-linking activity. Binds along the sides of the F-actin. May be involved in neurite formation. Inhibits protein phosphatase 1-alpha activity. May play an important role in linking the actin cytoskeleton to the plasma membrane at the synaptic junction"	figure legend:st1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10116(rat-brain-cortex)|taxid:10116(Rattus norvegicus brain cortex)	-	2020/10/30	2020/10/30	rogid:DtE+ZXAZKdCMvUW5K+jXQ5bH07M10116	rogid:rAffd872YQ4gBOE+4b71EkpnRMk10116	rigid:3wclwrjZRvafcOruQOYnegkn54c	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q5XIE8	uniprotkb:O88871	intact:EBI-15348306|ensembl:ENSRNOP00000023037	intact:EBI-7090239|intact:MINT-1889821|uniprotkb:Q9QWU2|uniprotkb:Q9JK36	psi-mi:itm2b_rat(display_long)|uniprotkb:Itm2b(gene name)|psi-mi:Itm2b(display_short)|uniprotkb:Immature BRI2(gene name synonym)|uniprotkb:Transmembrane protein BRI(gene name synonym)	psi-mi:gabr2_rat(display_long)|uniprotkb:Gabbr2(gene name)|psi-mi:Gabbr2(display_short)|uniprotkb:Gpr51(gene name synonym)|uniprotkb:G-protein coupled receptor 51(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Martins et al. (2018)	imex:IM-28469|pubmed:29476059	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26439741|imex:IM-28469-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSRNOG00000016271(gene)|ensembl:ENSRNOT00000023037(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001540"(amyloid-beta binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0010008"(endosome membrane)|go:"GO:0030660"(Golgi-associated vesicle membrane)|go:"GO:0031301"(integral component of organelle membrane)|go:"GO:0042985"(negative regulation of amyloid precursor protein biosynthetic process)|interpro:IPR007084(BRICHOS)|interpro:IPR040145|mint:Q5XIE8|refseq:NP_001006964.1|rgd:620727	mint:O88871|go:"GO:0004888"(transmembrane signaling receptor activity)|go:"GO:0004965"(G protein-coupled GABA receptor activity)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0007214"(gamma-aminobutyric acid signaling pathway)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030425"(dendrite)|go:"GO:0038039"(G protein-coupled receptor heterodimeric complex)|go:"GO:0043005"(neuron projection)|go:"GO:0043204"(perikaryon)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0098982"(GABA-ergic synapse)|go:"GO:0099055"(integral component of postsynaptic membrane)|go:"GO:0099056"(integral component of presynaptic membrane)|go:"GO:0150099"(neuron-glial cell signaling)|go:"GO:1902710"(GABA receptor complex)|reactome:R-RNO-1296041|reactome:R-RNO-418594|reactome:R-RNO-420499|reactome:R-RNO-977444|reactome:R-RNO-997272|go:"GO:0005737"(cytoplasm)|interpro:IPR017978|refseq:NP_113990.1|rgd:619864|interpro:IPR017979|interpro:IPR028082|interpro:IPR000337(GPCR, family 3)|interpro:IPR001828(Extracellular ligand-binding receptor)|interpro:IPR002455(GPCR, family 3, gamma-aminobutyric acid receptor, type B)|interpro:IPR002457(GPCR, family 3, gamma-aminobutyric acid receptor, type B2)|interpro:IPR041689	-	-	comment:mint|function:"Receptor for GABA. The activity of this receptor is mediated by G-proteins that inhibit adenylyl cyclase activity, stimulates phospholipase A2, activates potassium channels, inactivates voltage-dependent calcium-channels and modulates inositol phospholipids hydrolysis. Plays a critical role in the fine-tuning of inhibitory synaptic transmission. Pre-synaptic GABA-B-R inhibit neurotransmitter release by down-regulating high-voltage activated calcium channels, whereas postsynaptic GABA-B-R decrease neuronal excitability by activating a prominent inwardly rectifying potassium (Kir) conductance that underlies the late inhibitory postsynaptic potentials. Not only implicated in synaptic inhibition but also in hippocampal long-term potentiation, slow wave sleep, muscle relaxation and antinociception"|comment:homomint	figure legend:st1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10116(rat-brain-cortex)|taxid:10116(Rattus norvegicus brain cortex)	-	2020/10/30	2020/10/30	rogid:DtE+ZXAZKdCMvUW5K+jXQ5bH07M10116	rogid:2KtIPgSLdOYAmc34lA/U+dOtAow10116	rigid:3wclwrjZRvafcOruQOYnegkn54c	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q5XIE8	uniprotkb:O88339	intact:EBI-15348306|ensembl:ENSRNOP00000023037	intact:EBI-7066728|intact:MINT-101104	psi-mi:itm2b_rat(display_long)|uniprotkb:Itm2b(gene name)|psi-mi:Itm2b(display_short)|uniprotkb:Immature BRI2(gene name synonym)|uniprotkb:Transmembrane protein BRI(gene name synonym)	psi-mi:epn1_rat(display_long)|uniprotkb:Epn1(gene name)|psi-mi:Epn1(display_short)|uniprotkb:EPS-15-interacting protein 1(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Martins et al. (2018)	imex:IM-28469|pubmed:29476059	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26439741|imex:IM-28469-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSRNOG00000016271(gene)|ensembl:ENSRNOT00000023037(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001540"(amyloid-beta binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0010008"(endosome membrane)|go:"GO:0030660"(Golgi-associated vesicle membrane)|go:"GO:0031301"(integral component of organelle membrane)|go:"GO:0042985"(negative regulation of amyloid precursor protein biosynthetic process)|interpro:IPR007084(BRICHOS)|interpro:IPR040145|mint:Q5XIE8|refseq:NP_001006964.1|rgd:620727	mint:O88339|go:"GO:1905445"(positive regulation of clathrin coat assembly)|interpro:IPR003903(Ubiquitin interacting motif)|interpro:IPR008942(ENTH/VHS)|interpro:IPR013809(Epsin-like, N-terminal)|rcsb pdb:1EDU|rcsb pdb:1EYH|rcsb pdb:1H0A|rcsb pdb:1KY6|reactome:R-RNO-182971|reactome:R-RNO-8856825|reactome:R-RNO-8856828|go:"GO:1903671"(negative regulation of sprouting angiogenesis)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0005543"(phospholipid binding)|go:"GO:0005634"(nucleus)|go:"GO:0005768"(endosome)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005905"(clathrin-coated pit)|go:"GO:0006897"(endocytosis)|go:"GO:0007219"(Notch signaling pathway)|go:"GO:0007565"(female pregnancy)|go:"GO:0030125"(clathrin vesicle coat)|go:"GO:0030276"(clathrin binding)|go:"GO:0031234"(extrinsic component of cytoplasmic side of plasma membrane)|go:"GO:0035615"(clathrin adaptor activity)|go:"GO:0043195"(terminal bouton)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0048568"(embryonic organ development)|go:"GO:0090148"(membrane fission)|go:"GO:0098685"(Schaffer collateral - CA1 synapse)|go:"GO:0098793"(presynapse)|go:"GO:0098794"(postsynapse)|go:"GO:0098888"(extrinsic component of presynaptic membrane)|go:"GO:0098890"(extrinsic component of postsynaptic membrane)|rgd:619772|refseq:NP_476477.1|dip:DIP-40738N	-	-	comment:mint|function:"Binds to membranes enriched in phosphatidylinositol-4,5-biphosphate (PtdIns(4,5)P2). Modifies membrane curvature and facilitates the formation of clathrin-coated invaginations. Regulates receptor-mediated endocytosis"	figure legend:st1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10116(rat-brain-cortex)|taxid:10116(Rattus norvegicus brain cortex)	-	2020/10/30	2020/10/30	rogid:DtE+ZXAZKdCMvUW5K+jXQ5bH07M10116	rogid:HSxImXvS6/UJyI9kGWz36B0oxiM10116	rigid:3wclwrjZRvafcOruQOYnegkn54c	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q5XIE8	uniprotkb:Q6GMN2	intact:EBI-15348306|ensembl:ENSRNOP00000023037	intact:EBI-6997402|ensembl:ENSRNOP00000005687|intact:MINT-93063|uniprotkb:Q923H3	psi-mi:itm2b_rat(display_long)|uniprotkb:Itm2b(gene name)|psi-mi:Itm2b(display_short)|uniprotkb:Immature BRI2(gene name synonym)|uniprotkb:Transmembrane protein BRI(gene name synonym)	psi-mi:baip2_rat(display_long)|uniprotkb:Baiap2(gene name)|psi-mi:Baiap2(display_short)|uniprotkb:Insulin receptor tyrosine kinase substrate protein p53(gene name synonym)|uniprotkb:Insulin receptor substrate protein of 53 kDa(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Martins et al. (2018)	imex:IM-28469|pubmed:29476059	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26439741|imex:IM-28469-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSRNOG00000016271(gene)|ensembl:ENSRNOT00000023037(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001540"(amyloid-beta binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0010008"(endosome membrane)|go:"GO:0030660"(Golgi-associated vesicle membrane)|go:"GO:0031301"(integral component of organelle membrane)|go:"GO:0042985"(negative regulation of amyloid precursor protein biosynthetic process)|interpro:IPR007084(BRICHOS)|interpro:IPR040145|mint:Q5XIE8|refseq:NP_001006964.1|rgd:620727	refseq:XP_006247931.1|ensembl:ENSRNOG00000004049(gene)|ensembl:ENSRNOT00000005687(transcript)|go:"GO:0001221"(transcription coregulator binding)|go:"GO:0001726"(ruffle)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005791"(rough endoplasmic reticulum)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0005874"(microtubule)|go:"GO:0005886"(plasma membrane)|go:"GO:0007009"(plasma membrane organization)|go:"GO:0007420"(brain development)|go:"GO:0008093"(cytoskeletal anchor activity)|go:"GO:0008360"(regulation of cell shape)|go:"GO:0009617"(response to bacterium)|go:"GO:0010976"(positive regulation of neuron projection development)|go:"GO:0014069"(postsynaptic density)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0016358"(dendrite development)|go:"GO:0030027"(lamellipodium)|go:"GO:0030141"(secretory granule)|go:"GO:0030165"(PDZ domain binding)|go:"GO:0030175"(filopodium)|go:"GO:0030182"(neuron differentiation)|go:"GO:0030838"(positive regulation of actin filament polymerization)|go:"GO:0032956"(regulation of actin cytoskeleton organization)|go:"GO:0035418"(protein localization to synapse)|go:"GO:0042802"(identical protein binding)|go:"GO:0043005"(neuron projection)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043197"(dendritic spine)|go:"GO:0043198"(dendritic shaft)|go:"GO:0044306"(neuron projection terminus)|go:"GO:0048167"(regulation of synaptic plasticity)|go:"GO:0050804"(modulation of chemical synaptic transmission)|go:"GO:0051017"(actin filament bundle assembly)|go:"GO:0051764"(actin crosslink formation)|go:"GO:0060076"(excitatory synapse)|go:"GO:0061003"(positive regulation of dendritic spine morphogenesis)|go:"GO:0061845"(neuron projection branch point)|go:"GO:0061846"(dendritic spine cytoplasm)|go:"GO:0070064"(proline-rich region binding)|go:"GO:0071364"(cellular response to epidermal growth factor stimulus)|go:"GO:0097060"(synaptic membrane)|go:"GO:0097110"(scaffold protein binding)|go:"GO:0098685"(Schaffer collateral - CA1 synapse)|go:"GO:0098793"(presynapse)|go:"GO:0098794"(postsynapse)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099092"(postsynaptic density, intracellular component)|go:"GO:0099523"(presynaptic cytosol)|go:"GO:0099524"(postsynaptic cytosol)|go:"GO:0099564"(modification of synaptic structure, modulating synaptic transmission)|go:"GO:1905232"(cellular response to L-glutamate)|go:"GO:1905274"(regulation of modification of postsynaptic actin cytoskeleton)|go:"GO:2000251"(positive regulation of actin cytoskeleton reorganization)|go:"GO:2000463"(positive regulation of excitatory postsynaptic potential)|interpro:IPR001452(Src homology-3)|interpro:IPR013606("IRSp53/MIM homology domain (IMD)")|interpro:IPR027267|interpro:IPR027681|interpro:IPR030128|interpro:IPR035594|interpro:IPR036028|mint:Q6GMN2|reactome:R-RNO-2029482|reactome:R-RNO-4420097|reactome:R-RNO-5663213|reactome:R-RNO-9013148|reactome:R-RNO-9013149|reactome:R-RNO-9013423|rgd:619814|refseq:NP_476544.1	-	-	comment:mint|function:Adapter protein that links membrane-bound small G-proteins to cytoplasmic effector proteins. Necessary for CDC42-mediated reorganization of the actin cytoskeleton and for RAC1-mediated membrane ruffling. Involved in the regulation of the actin cytoskeleton by WASF family members and the Arp2/3 complex. Plays a role in neurite growth. Acts syngeristically with ENAH to promote filipodia formation|comment:homomint	figure legend:st1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10116(rat-brain-cortex)|taxid:10116(Rattus norvegicus brain cortex)	-	2020/10/30	2020/10/30	rogid:DtE+ZXAZKdCMvUW5K+jXQ5bH07M10116	rogid:0d4uTvCvzszf08CQgfD7BGdUvYA10116	rigid:3wclwrjZRvafcOruQOYnegkn54c	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q5XIE8	uniprotkb:Q9Z1T4	intact:EBI-15348306|ensembl:ENSRNOP00000023037	intact:EBI-8548356|intact:MINT-1784567|uniprotkb:Q9R093|ensembl:ENSRNOP00000009802	psi-mi:itm2b_rat(display_long)|uniprotkb:Itm2b(gene name)|psi-mi:Itm2b(display_short)|uniprotkb:Immature BRI2(gene name synonym)|uniprotkb:Transmembrane protein BRI(gene name synonym)	psi-mi:cnkr2_rat(display_long)|uniprotkb:Cnksr2(gene name)|psi-mi:Cnksr2(display_short)|uniprotkb:Membrane-associated guanylate kinase-interacting protein(gene name synonym)|uniprotkb:CNK homolog protein 2(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Martins et al. (2018)	imex:IM-28469|pubmed:29476059	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26439741|imex:IM-28469-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSRNOG00000016271(gene)|ensembl:ENSRNOT00000023037(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001540"(amyloid-beta binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0010008"(endosome membrane)|go:"GO:0030660"(Golgi-associated vesicle membrane)|go:"GO:0031301"(integral component of organelle membrane)|go:"GO:0042985"(negative regulation of amyloid precursor protein biosynthetic process)|interpro:IPR007084(BRICHOS)|interpro:IPR040145|mint:Q5XIE8|refseq:NP_001006964.1|rgd:620727	refseq:NP_001106837.1|rgd:708454|refseq:NP_067718.1|ensembl:ENSRNOG00000007014(gene)|ensembl:ENSRNOT00000009802(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0009966"(regulation of signal transduction)|go:"GO:0014069"(postsynaptic density)|go:"GO:0019901"(protein kinase binding)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0042802"(identical protein binding)|go:"GO:0043005"(neuron projection)|go:"GO:0043025"(neuronal cell body)|go:"GO:0045211"(postsynaptic membrane)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099147"(extrinsic component of postsynaptic density membrane)|go:"GO:0099173"(postsynapse organization)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR001660(Sterile alpha motif SAM)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR010599(Connector enhancer of kinase suppressor of ras 2)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR013761(Sterile alpha motif-type)|interpro:IPR017874|interpro:IPR036034|mint:Q9Z1T4|reactome:R-RNO-5674135	-	-	comment:mint|function:May function as an adapter protein or regulator of Ras signaling pathways, in synaptic junctions	figure legend:st1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10116(rat-brain-cortex)|taxid:10116(Rattus norvegicus brain cortex)	-	2020/10/30	2020/10/30	rogid:DtE+ZXAZKdCMvUW5K+jXQ5bH07M10116	rogid:4/s+PX8m0iFFkYYA7KN3JIUQIK410116	rigid:3wclwrjZRvafcOruQOYnegkn54c	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q5XIE8	uniprotkb:Q6QLM7	intact:EBI-15348306|ensembl:ENSRNOP00000023037	intact:EBI-8053424|intact:UNK-5485260	psi-mi:itm2b_rat(display_long)|uniprotkb:Itm2b(gene name)|psi-mi:Itm2b(display_short)|uniprotkb:Immature BRI2(gene name synonym)|uniprotkb:Transmembrane protein BRI(gene name synonym)	psi-mi:kif5a_rat(display_long)|uniprotkb:Kinesin heavy chain neuron-specific 1(gene name synonym)|uniprotkb:Neuronal kinesin heavy chain(gene name synonym)|uniprotkb:Kif5a(gene name)|psi-mi:Kif5a(display_short)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Martins et al. (2018)	imex:IM-28469|pubmed:29476059	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26439741|imex:IM-28469-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSRNOG00000016271(gene)|ensembl:ENSRNOT00000023037(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001540"(amyloid-beta binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0010008"(endosome membrane)|go:"GO:0030660"(Golgi-associated vesicle membrane)|go:"GO:0031301"(integral component of organelle membrane)|go:"GO:0042985"(negative regulation of amyloid precursor protein biosynthetic process)|interpro:IPR007084(BRICHOS)|interpro:IPR040145|mint:Q5XIE8|refseq:NP_001006964.1|rgd:620727	rgd:1303035|refseq:NP_997688.1|mint:Q6QLM7|dip:DIP-46364N|go:"GO:0008574"(plus-end-directed microtubule motor activity)|go:"GO:0016192"(vesicle-mediated transport)|go:"GO:0019894"(kinesin binding)|go:"GO:0021766"(hippocampus development)|go:"GO:0021794"(thalamus development)|go:"GO:0021987"(cerebral cortex development)|go:"GO:0030424"(axon)|go:"GO:0030425"(dendrite)|go:"GO:0030705"(cytoskeleton-dependent intracellular transport)|go:"GO:0032839"(dendrite cytoplasm)|go:"GO:0035253"(ciliary rootlet)|go:"GO:0043005"(neuron projection)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043204"(perikaryon)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0048489"(synaptic vesicle transport)|go:"GO:0048666"(neuron development)|go:"GO:0071361"(cellular response to ethanol)|go:"GO:0090724"(central region of growth cone)|go:"GO:0097110"(scaffold protein binding)|go:"GO:0097440"(apical dendrite)|go:"GO:0098971"(anterograde dendritic transport of neurotransmitter receptor complex)|go:"GO:0099641"(anterograde axonal protein transport)|go:"GO:1904115"(axon cytoplasm)|go:"GO:1904647"(response to rotenone)|go:"GO:1990049"(retrograde neuronal dense core vesicle transport)|go:"GO:1990090"(cellular response to nerve growth factor stimulus)|interpro:IPR001752(Kinesin, motor region)|interpro:IPR027640|interpro:IPR036961|rcsb pdb:2KIN|interpro:IPR027417|rcsb pdb:3KIN|reactome:R-RNO-2132295|reactome:R-RNO-5625970|reactome:R-RNO-6811434|reactome:R-RNO-983189|go:"GO:0000932"(P-body)|go:"GO:0003777"(microtubule motor activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005871"(kinesin complex)|go:"GO:0005874"(microtubule)|go:"GO:0007017"(microtubule-based process)|go:"GO:0007018"(microtubule-based movement)|go:"GO:0007411"(axon guidance)|go:"GO:0008017"(microtubule binding)	-	-	comment:mint|comment:homomint|function:"Microtubule-dependent motor required for slow axonal transport of neurofilament proteins (NFH, NFM and NFL)"	figure legend:st1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10116(rat-brain-cortex)|taxid:10116(Rattus norvegicus brain cortex)	-	2020/10/30	2020/10/30	rogid:DtE+ZXAZKdCMvUW5K+jXQ5bH07M10116	rogid:8Rs5XnQSfYtBkTw31UqIBAtb/wY10116	rigid:3wclwrjZRvafcOruQOYnegkn54c	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q5XIE8	uniprotkb:Q7TQ16	intact:EBI-15348306|ensembl:ENSRNOP00000023037	intact:EBI-7626900|intact:UNK-5495741|ensembl:ENSRNOP00000065074	psi-mi:itm2b_rat(display_long)|uniprotkb:Itm2b(gene name)|psi-mi:Itm2b(display_short)|uniprotkb:Immature BRI2(gene name synonym)|uniprotkb:Transmembrane protein BRI(gene name synonym)	psi-mi:qcr8_rat(display_long)|uniprotkb:Uqcrq(gene name)|psi-mi:Uqcrq(display_short)|uniprotkb:Complex III subunit 8(gene name synonym)|uniprotkb:Complex III subunit VIII(gene name synonym)|uniprotkb:Low molecular mass ubiquinone-binding protein(gene name synonym)|uniprotkb:Qpc(gene name synonym)|uniprotkb:Ubiquinol-cytochrome c reductase complex 9.5 kDa protein(gene name synonym)|uniprotkb:Ubiquinol-cytochrome c reductase complex ubiquinone-binding protein QP-C(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Martins et al. (2018)	imex:IM-28469|pubmed:29476059	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26439741|imex:IM-28469-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSRNOG00000016271(gene)|ensembl:ENSRNOT00000023037(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001540"(amyloid-beta binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0010008"(endosome membrane)|go:"GO:0030660"(Golgi-associated vesicle membrane)|go:"GO:0031301"(integral component of organelle membrane)|go:"GO:0042985"(negative regulation of amyloid precursor protein biosynthetic process)|interpro:IPR007084(BRICHOS)|interpro:IPR040145|mint:Q5XIE8|refseq:NP_001006964.1|rgd:620727	refseq:NP_001020305.1|rgd:1562350|ensembl:ENSRNOG00000048174(gene)|ensembl:ENSRNOT00000073964(transcript)|go:"GO:0005739"(mitochondrion)|go:"GO:0005750"(mitochondrial respiratory chain complex III)|go:"GO:0006122"(mitochondrial electron transport, ubiquinol to cytochrome c)|go:"GO:0021539"(subthalamus development)|go:"GO:0021548"(pons development)|go:"GO:0021680"(cerebellar Purkinje cell layer development)|go:"GO:0021766"(hippocampus development)|go:"GO:0021794"(thalamus development)|go:"GO:0021854"(hypothalamus development)|go:"GO:0021860"(pyramidal neuron development)|go:"GO:0030901"(midbrain development)|go:"GO:1902600"(proton transmembrane transport)|interpro:IPR036642|mint:Q7TQ16|reactome:R-RNO-611105|interpro:IPR004205(UcrQ)|refseq:XP_006246378.1	-	-	comment:mint	figure legend:st1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10116(rat-brain-cortex)|taxid:10116(Rattus norvegicus brain cortex)	-	2020/10/30	2020/10/30	rogid:DtE+ZXAZKdCMvUW5K+jXQ5bH07M10116	rogid:3bMevxh5qeqP+F+G2L+pD+rBK6s10116	rigid:3wclwrjZRvafcOruQOYnegkn54c	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q5XIE8	uniprotkb:P62744	intact:EBI-15348306|ensembl:ENSRNOP00000023037	intact:EBI-7617461|uniprotkb:P70626|uniprotkb:Q00380|uniprotkb:P97626|intact:MINT-2514729|ensembl:ENSRNOP00000021310	psi-mi:itm2b_rat(display_long)|uniprotkb:Itm2b(gene name)|psi-mi:Itm2b(display_short)|uniprotkb:Immature BRI2(gene name synonym)|uniprotkb:Transmembrane protein BRI(gene name synonym)	psi-mi:ap2s1_rat(display_long)|uniprotkb:Clathrin assembly protein 2 sigma small chain(gene name synonym)|uniprotkb:Ap2s1(gene name)|psi-mi:Ap2s1(display_short)|uniprotkb:Ap17(gene name synonym)|uniprotkb:Claps2(gene name synonym)|uniprotkb:Adaptor protein complex AP-2 subunit sigma(gene name synonym)|uniprotkb:Sigma2-adaptin(gene name synonym)|uniprotkb:Sigma-adaptin 3b(gene name synonym)|uniprotkb:Plasma membrane adaptor AP-2 17 kDa protein(gene name synonym)|uniprotkb:Clathrin coat assembly protein AP17(gene name synonym)|uniprotkb:Clathrin coat-associated protein AP17(gene name synonym)|uniprotkb:Adaptor-related protein complex 2 subunit sigma(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Martins et al. (2018)	imex:IM-28469|pubmed:29476059	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26439741|imex:IM-28469-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSRNOG00000016271(gene)|ensembl:ENSRNOT00000023037(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001540"(amyloid-beta binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0010008"(endosome membrane)|go:"GO:0030660"(Golgi-associated vesicle membrane)|go:"GO:0031301"(integral component of organelle membrane)|go:"GO:0042985"(negative regulation of amyloid precursor protein biosynthetic process)|interpro:IPR007084(BRICHOS)|interpro:IPR040145|mint:Q5XIE8|refseq:NP_001006964.1|rgd:620727	rgd:620188|refseq:NP_075241.2|ensembl:ENSRNOG00000015865(gene)|ensembl:ENSRNOT00000021310(transcript)|go:"GO:0005886"(plasma membrane)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0016192"(vesicle-mediated transport)|go:"GO:0030122"(AP-2 adaptor complex)|go:"GO:0035615"(clathrin adaptor activity)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0072583"(clathrin-dependent endocytosis)|interpro:IPR000804(Clathrin adaptor, sigma subunit/coatomer, zeta subunit)|interpro:IPR011012(Longin-like)|interpro:IPR016635(Adaptor protein complex, sigma subunit)|interpro:IPR022775|interpro:IPR027156|rcsb pdb:4NEE|rcsb pdb:6OWO|rcsb pdb:6OWT|rcsb pdb:6OXL|reactome:R-RNO-177504|reactome:R-RNO-2132295|reactome:R-RNO-416993|reactome:R-RNO-437239|reactome:R-RNO-5099900|reactome:R-RNO-5140745|reactome:R-RNO-8856825|reactome:R-RNO-8856828|reactome:R-RNO-8866427|reactome:R-RNO-8964038|mint:P62744	-	-	function:Component of the adaptor complexes which link clathrin to receptors in coated vesicles. Clathrin-associated protein complexes are believed to interact with the cytoplasmic tails of membrane proteins, leading to their selection and concentration. AP2S1/AP17 is a subunit of the plasma membrane adaptor. The complex binds polyphosphoinositides|comment:mint	figure legend:st1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10116(rat-brain-cortex)|taxid:10116(Rattus norvegicus brain cortex)	-	2020/10/30	2020/10/30	rogid:DtE+ZXAZKdCMvUW5K+jXQ5bH07M10116	rogid:AJxHeeoCpwPxjsRcAQkiAGaC9k010116	rigid:3wclwrjZRvafcOruQOYnegkn54c	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q5XIE8	uniprotkb:P62944	intact:EBI-15348306|ensembl:ENSRNOP00000023037	intact:EBI-7048246|ensembl:ENSRNOP00000072290|uniprotkb:P21851|intact:MINT-122517	psi-mi:itm2b_rat(display_long)|uniprotkb:Itm2b(gene name)|psi-mi:Itm2b(display_short)|uniprotkb:Immature BRI2(gene name synonym)|uniprotkb:Transmembrane protein BRI(gene name synonym)	psi-mi:ap2b1_rat(display_long)|uniprotkb:Ap2b1(gene name)|psi-mi:Ap2b1(display_short)|uniprotkb:Clapb1(gene name synonym)|uniprotkb:Beta-adaptin(gene name synonym)|uniprotkb:Plasma membrane adaptor HA2/AP2 adaptin beta subunit(gene name synonym)|uniprotkb:Clathrin assembly protein complex 2 beta large chain(gene name synonym)|uniprotkb:AP105B(gene name synonym)|uniprotkb:Adaptor protein complex AP-2 subunit beta(gene name synonym)|uniprotkb:Beta-2-adaptin(gene name synonym)|uniprotkb:Adaptor-related protein complex 2 subunit beta(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Martins et al. (2018)	imex:IM-28469|pubmed:29476059	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26439741|imex:IM-28469-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSRNOG00000016271(gene)|ensembl:ENSRNOT00000023037(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001540"(amyloid-beta binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0010008"(endosome membrane)|go:"GO:0030660"(Golgi-associated vesicle membrane)|go:"GO:0031301"(integral component of organelle membrane)|go:"GO:0042985"(negative regulation of amyloid precursor protein biosynthetic process)|interpro:IPR007084(BRICHOS)|interpro:IPR040145|mint:Q5XIE8|refseq:NP_001006964.1|rgd:620727	refseq:XP_008766157.1|refseq:XP_008766158.1|refseq:XP_008766159.1|refseq:XP_008766160.1|refseq:XP_008766161.1|ensembl:ENSRNOG00000061543(gene)|ensembl:ENSRNOT00000085799(transcript)|go:"GO:0001822"(kidney development)|go:"GO:0003279"(cardiac septum development)|go:"GO:0003281"(ventricular septum development)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0007507"(heart development)|go:"GO:0016192"(vesicle-mediated transport)|go:"GO:0030118"(clathrin coat)|go:"GO:0030119"(AP-type membrane coat adaptor complex)|go:"GO:0030122"(AP-2 adaptor complex)|go:"GO:0030131"(clathrin adaptor complex)|go:"GO:0030276"(clathrin binding)|go:"GO:0035904"(aorta development)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045807"(positive regulation of endocytosis)|go:"GO:0048268"(clathrin coat assembly)|go:"GO:0060976"(coronary vasculature development)|go:"GO:0098794"(postsynapse)|go:"GO:0098884"(postsynaptic neurotransmitter receptor internalization)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099590"(neurotransmitter receptor internalization)|go:"GO:1901215"(negative regulation of neuron death)|go:"GO:1905477"(positive regulation of protein localization to membrane)|interpro:IPR000225(Armadillo)|interpro:IPR002553(Clathrin/coatomer adaptor, adaptin-like, N-terminal)|interpro:IPR008152(Clathrin adaptor, alpha/beta/gamma-adaptin, appendage, Ig-like subdomain)|interpro:IPR009028(Clathrin/coatomer adaptor, adaptin-like, appendage, C-terminal subdomain)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR012295(Beta2-adaptin/TATA-box binding, C-terminal)|interpro:IPR013037(Clathrin adaptor, beta-adaptin, appendage, Ig-like subdomain)|interpro:IPR013041(Clathrin/coatomer adaptor, adaptin-like, appendage, Ig-like subdomain)|interpro:IPR015151(Clathrin adaptor, beta-adaptin, appendage, C-terminal subdomain)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR016342(Adaptor protein complex, beta subunit)|interpro:IPR026739|mint:P62944|rcsb pdb:3H1Z|rcsb pdb:3HS9|rcsb pdb:6OWT|reactome:R-RNO-177504|reactome:R-RNO-2132295|reactome:R-RNO-416993|reactome:R-RNO-437239|reactome:R-RNO-5099900|reactome:R-RNO-5140745|go:"GO:0072583"(clathrin-dependent endocytosis)|reactome:R-RNO-8856825|reactome:R-RNO-8856828|reactome:R-RNO-8866427|reactome:R-RNO-8964038|refseq:XP_017452462.1|refseq:NP_542150.1|rgd:71048|dip:DIP-40944N	-	-	function:Component of the adaptor complexes which link clathrin to receptors in coated vesicles. Clathrin-associated protein complexes are believed to interact with the cytoplasmic tails of membrane proteins, leading to their selection and concentration. AP2B1 is a subunit of the plasma membrane adaptor. The complex binds polyphosphoinositides|comment:mint	figure legend:st1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10116(rat-brain-cortex)|taxid:10116(Rattus norvegicus brain cortex)	-	2020/10/30	2020/10/30	rogid:DtE+ZXAZKdCMvUW5K+jXQ5bH07M10116	rogid:Q5oFhdE1hcmqu7xLG3MteCu0Zcg10116	rigid:3wclwrjZRvafcOruQOYnegkn54c	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q5XIE8	uniprotkb:O35458	intact:EBI-15348306|ensembl:ENSRNOP00000023037	intact:EBI-7281062|intact:UNK-5362087|ensembl:ENSRNOP00000020720	psi-mi:itm2b_rat(display_long)|uniprotkb:Itm2b(gene name)|psi-mi:Itm2b(display_short)|uniprotkb:Immature BRI2(gene name synonym)|uniprotkb:Transmembrane protein BRI(gene name synonym)	psi-mi:viaat_rat(display_long)|uniprotkb:Slc32a1(gene name)|psi-mi:Slc32a1(display_short)|uniprotkb:Vgat(gene name synonym)|uniprotkb:Viaat(gene name synonym)|uniprotkb:GABA and glycine transporter(gene name synonym)|uniprotkb:Vesicular GABA transporter(gene name synonym)|uniprotkb:Solute carrier family 32 member 1(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Martins et al. (2018)	imex:IM-28469|pubmed:29476059	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26439741|imex:IM-28469-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSRNOG00000016271(gene)|ensembl:ENSRNOT00000023037(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001540"(amyloid-beta binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0010008"(endosome membrane)|go:"GO:0030660"(Golgi-associated vesicle membrane)|go:"GO:0031301"(integral component of organelle membrane)|go:"GO:0042985"(negative regulation of amyloid precursor protein biosynthetic process)|interpro:IPR007084(BRICHOS)|interpro:IPR040145|mint:Q5XIE8|refseq:NP_001006964.1|rgd:620727	refseq:XP_006235503.1|refseq:NP_113970.1|rgd:621402|ensembl:ENSRNOG00000015393(gene)|ensembl:ENSRNOT00000020720(transcript)|go:"GO:0005886"(plasma membrane)|go:"GO:0006836"(neurotransmitter transport)|go:"GO:0007568"(aging)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0015187"(glycine transmembrane transporter activity)|go:"GO:0015495"("gamma-aminobutyric acid:proton symporter activity")|go:"GO:0015812"(gamma-aminobutyric acid transport)|go:"GO:0015816"(glycine transport)|go:"GO:0016021"(integral component of membrane)|go:"GO:0021766"(hippocampus development)|go:"GO:0030285"(integral component of synaptic vesicle membrane)|go:"GO:0030425"(dendrite)|go:"GO:0043005"(neuron projection)|go:"GO:0043229"(intracellular organelle)|go:"GO:0044292"(dendrite terminus)|go:"GO:0044306"(neuron projection terminus)|go:"GO:0044316"(cone cell pedicle)|go:"GO:0045202"(synapse)|go:"GO:0048786"(presynaptic active zone)|go:"GO:0051286"(cell tip)|go:"GO:0060077"(inhibitory synapse)|go:"GO:0098700"(neurotransmitter loading into synaptic vesicle)|go:"GO:0098982"(GABA-ergic synapse)|interpro:IPR013057(Amino acid transporter, transmembrane)|mint:O35458|reactome:R-RNO-425393|reactome:R-RNO-888590	-	-	function:Involved in the uptake of GABA and glycine into the synaptic vesicles|comment:mint	figure legend:st1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10116(rat-brain-cortex)|taxid:10116(Rattus norvegicus brain cortex)	-	2020/10/30	2020/10/30	rogid:DtE+ZXAZKdCMvUW5K+jXQ5bH07M10116	rogid:yejLVaYBDG3n2gt6XV8lN868NYk10116	rigid:3wclwrjZRvafcOruQOYnegkn54c	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q5XIE8	uniprotkb:Q62634	intact:EBI-15348306|ensembl:ENSRNOP00000023037	intact:EBI-7280977|intact:MINT-4784487|uniprotkb:A9LRT0|ensembl:ENSRNOP00000028064	psi-mi:itm2b_rat(display_long)|uniprotkb:Itm2b(gene name)|psi-mi:Itm2b(display_short)|uniprotkb:Immature BRI2(gene name synonym)|uniprotkb:Transmembrane protein BRI(gene name synonym)	psi-mi:vglu1_rat(display_long)|uniprotkb:Slc17a7(gene name)|psi-mi:Slc17a7(display_short)|uniprotkb:Bnpi(gene name synonym)|uniprotkb:Vglut1(gene name synonym)|uniprotkb:Solute carrier family 17 member 7(gene name synonym)|uniprotkb:"Brain-specific Na(+)-dependent inorganic phosphate cotransporter"(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Martins et al. (2018)	imex:IM-28469|pubmed:29476059	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26439741|imex:IM-28469-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSRNOG00000016271(gene)|ensembl:ENSRNOT00000023037(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001540"(amyloid-beta binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0010008"(endosome membrane)|go:"GO:0030660"(Golgi-associated vesicle membrane)|go:"GO:0031301"(integral component of organelle membrane)|go:"GO:0042985"(negative regulation of amyloid precursor protein biosynthetic process)|interpro:IPR007084(BRICHOS)|interpro:IPR040145|mint:Q5XIE8|refseq:NP_001006964.1|rgd:620727	rgd:620101|refseq:NP_446311.1|ensembl:ENSRNOG00000020650(gene)|ensembl:ENSRNOT00000028064(transcript)|go:"GO:0003407"(neural retina development)|go:"GO:0005313"(L-glutamate transmembrane transporter activity)|go:"GO:0005315"(inorganic phosphate transmembrane transporter activity)|go:"GO:0005326"(neurotransmitter transmembrane transporter activity)|go:"GO:0005436"("sodium:phosphate symporter activity")|go:"GO:0006817"(phosphate ion transport)|go:"GO:0007268"(chemical synaptic transmission)|go:"GO:0007420"(brain development)|go:"GO:0007616"(long-term memory)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0008068"(extracellularly glutamate-gated chloride channel activity)|go:"GO:0015319"("sodium:inorganic phosphate symporter activity")|go:"GO:0016021"(integral component of membrane)|go:"GO:0022857"(transmembrane transporter activity)|go:"GO:0030285"(integral component of synaptic vesicle membrane)|go:"GO:0030672"(synaptic vesicle membrane)|go:"GO:0035249"(synaptic transmission, glutamatergic)|go:"GO:0042137"(sequestering of neurotransmitter)|go:"GO:0043229"(intracellular organelle)|go:"GO:0044300"(cerebellar mossy fiber)|go:"GO:0045202"(synapse)|go:"GO:0048786"(presynaptic active zone)|go:"GO:0050803"(regulation of synapse structure or activity)|go:"GO:0051938"(L-glutamate import)|go:"GO:0060076"(excitatory synapse)|go:"GO:0060079"(excitatory postsynaptic potential)|go:"GO:0097401"(synaptic vesicle lumen acidification)|go:"GO:0098700"(neurotransmitter loading into synaptic vesicle)|go:"GO:0098794"(postsynapse)|go:"GO:1900242"(regulation of synaptic vesicle endocytosis)|interpro:IPR011701(Major facilitator superfamily MFS-1)|interpro:IPR020846|interpro:IPR036259|mint:Q62634|reactome:R-RNO-210500|reactome:R-RNO-428643|go:"GO:0006820"(anion transport)	-	-	comment:mint	figure legend:st1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10116(rat-brain-cortex)|taxid:10116(Rattus norvegicus brain cortex)	-	2020/10/30	2020/10/30	rogid:DtE+ZXAZKdCMvUW5K+jXQ5bH07M10116	rogid:UbaEJLA0CIT48OoJn8wT3wgvP1s10116	rigid:3wclwrjZRvafcOruQOYnegkn54c	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q5XIE8	uniprotkb:D4AB66	intact:EBI-15348306|ensembl:ENSRNOP00000023037	intact:EBI-8514708|intact:MINT-8092238|ensembl:ENSRNOP00000005881	psi-mi:itm2b_rat(display_long)|uniprotkb:Itm2b(gene name)|psi-mi:Itm2b(display_short)|uniprotkb:Immature BRI2(gene name synonym)|uniprotkb:Transmembrane protein BRI(gene name synonym)	psi-mi:ston2_rat(display_long)|uniprotkb:Ston2(gene name)|psi-mi:Ston2(display_short)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Martins et al. (2018)	imex:IM-28469|pubmed:29476059	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26439741|imex:IM-28469-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSRNOG00000016271(gene)|ensembl:ENSRNOT00000023037(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001540"(amyloid-beta binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0010008"(endosome membrane)|go:"GO:0030660"(Golgi-associated vesicle membrane)|go:"GO:0031301"(integral component of organelle membrane)|go:"GO:0042985"(negative regulation of amyloid precursor protein biosynthetic process)|interpro:IPR007084(BRICHOS)|interpro:IPR040145|mint:Q5XIE8|refseq:NP_001006964.1|rgd:620727	rgd:1311502|refseq:NP_001129346.1|refseq:XP_006240468.1|refseq:XP_006240469.1|ensembl:ENSRNOG00000004458(gene)|ensembl:ENSRNOT00000005881(transcript)|go:"GO:0002244"(hematopoietic progenitor cell differentiation)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0016020"(membrane)|go:"GO:0016192"(vesicle-mediated transport)|go:"GO:0030100"(regulation of endocytosis)|go:"GO:0030136"(clathrin-coated vesicle)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0035615"(clathrin adaptor activity)|go:"GO:0043005"(neuron projection)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0048488"(synaptic vesicle endocytosis)|go:"GO:0098793"(presynapse)|interpro:IPR012320(Stonin homology)|interpro:IPR017110(Stonin)|interpro:IPR022699|interpro:IPR028565|interpro:IPR031228|interpro:IPR036168|mint:D4AB66|reactome:R-RNO-8856825|reactome:R-RNO-8856828	-	-	comment:mint	figure legend:st1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10116(rat-brain-cortex)|taxid:10116(Rattus norvegicus brain cortex)	-	2020/10/30	2020/10/30	rogid:DtE+ZXAZKdCMvUW5K+jXQ5bH07M10116	rogid:Ly8uUc9VzPOWrOk4jRtwrhzOHvQ10116	rigid:3wclwrjZRvafcOruQOYnegkn54c	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q5XIE8	uniprotkb:P97874	intact:EBI-15348306|ensembl:ENSRNOP00000023037	intact:EBI-6947879|intact:MINT-3289568	psi-mi:itm2b_rat(display_long)|uniprotkb:Itm2b(gene name)|psi-mi:Itm2b(display_short)|uniprotkb:Immature BRI2(gene name synonym)|uniprotkb:Transmembrane protein BRI(gene name synonym)	psi-mi:gak_rat(display_long)|uniprotkb:Gak(gene name)|psi-mi:Gak(display_short)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Martins et al. (2018)	imex:IM-28469|pubmed:29476059	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26439741|imex:IM-28469-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSRNOG00000016271(gene)|ensembl:ENSRNOT00000023037(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001540"(amyloid-beta binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0010008"(endosome membrane)|go:"GO:0030660"(Golgi-associated vesicle membrane)|go:"GO:0031301"(integral component of organelle membrane)|go:"GO:0042985"(negative regulation of amyloid precursor protein biosynthetic process)|interpro:IPR007084(BRICHOS)|interpro:IPR040145|mint:Q5XIE8|refseq:NP_001006964.1|rgd:620727	go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0005925"(focal adhesion)|go:"GO:0006898"(receptor-mediated endocytosis)|go:"GO:0007029"(endoplasmic reticulum organization)|go:"GO:0007030"(Golgi organization)|go:"GO:0007049"(cell cycle)|go:"GO:0009913"(epidermal cell differentiation)|go:"GO:0010977"(negative regulation of neuron projection development)|go:"GO:0030276"(clathrin binding)|go:"GO:0030332"(cyclin binding)|go:"GO:0031982"(vesicle)|go:"GO:0034067"(protein localization to Golgi apparatus)|go:"GO:0035622"(intrahepatic bile duct development)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0048468"(cell development)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0048853"(forebrain morphogenesis)|go:"GO:0061436"(establishment of skin barrier)|go:"GO:0072318"(clathrin coat disassembly)|go:"GO:0072583"(clathrin-dependent endocytosis)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0090160"(Golgi to lysosome transport)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:1905224"(clathrin-coated pit assembly)|go:"GO:2000179"(positive regulation of neural precursor cell proliferation)|reactome:R-RNO-432722|reactome:R-RNO-8856828|interpro:IPR000719(Protein kinase, core)|interpro:IPR001623(Heat shock protein DnaJ, N-terminal)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR035892|refseq:NP_112292.1|interpro:IPR014020(C2 tensin-type)|rgd:621589|interpro:IPR011009(Protein kinase-like)|interpro:IPR029021|interpro:IPR029023|mint:P97874|interpro:IPR036869	-	-	comment:mint|function:Associates with cyclin G and CDK5. Seems to act as an auxilin homolog that is involved in the uncoating of clathrin-coated vesicles by Hsc70 in non-neuronal cells. Expression oscillates slightly during the cell cycle, peaking at G1	figure legend:st1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10116(rat-brain-cortex)|taxid:10116(Rattus norvegicus brain cortex)	-	2020/10/30	2020/10/30	rogid:DtE+ZXAZKdCMvUW5K+jXQ5bH07M10116	rogid:Y8JA/CKcFHMi5e0baHUVN0RNYVM10116	rigid:3wclwrjZRvafcOruQOYnegkn54c	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q5XIE8	uniprotkb:P61983	intact:EBI-15348306|ensembl:ENSRNOP00000023037	intact:EBI-359821|uniprotkb:A0JPM0|uniprotkb:O70457|uniprotkb:Q9UDP2|uniprotkb:P35214|uniprotkb:Q9UN99|ensembl:ENSRNOP00000001954|ensembl:ENSRNOP00000069671	psi-mi:itm2b_rat(display_long)|uniprotkb:Itm2b(gene name)|psi-mi:Itm2b(display_short)|uniprotkb:Immature BRI2(gene name synonym)|uniprotkb:Transmembrane protein BRI(gene name synonym)	psi-mi:1433g_rat(display_long)|uniprotkb:Ywhag(gene name)|psi-mi:Ywhag(display_short)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Martins et al. (2018)	imex:IM-28469|pubmed:29476059	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26439741|imex:IM-28469-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSRNOG00000016271(gene)|ensembl:ENSRNOT00000023037(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001540"(amyloid-beta binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0010008"(endosome membrane)|go:"GO:0030660"(Golgi-associated vesicle membrane)|go:"GO:0031301"(integral component of organelle membrane)|go:"GO:0042985"(negative regulation of amyloid precursor protein biosynthetic process)|interpro:IPR007084(BRICHOS)|interpro:IPR040145|mint:Q5XIE8|refseq:NP_001006964.1|rgd:620727	rgd:62002|refseq:NP_062249.1|ensembl:ENSRNOG00000001436(gene)|ensembl:ENSRNOT00000001954(transcript)|ensembl:ENSRNOT00000084730(transcript)|go:"GO:0003779"(actin binding)|go:"GO:0005080"(protein kinase C binding)|go:"GO:0005159"(insulin-like growth factor receptor binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0006605"(protein targeting)|go:"GO:0007165"(signal transduction)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030234"(enzyme regulator activity)|go:"GO:0030971"(receptor tyrosine kinase binding)|go:"GO:0031982"(vesicle)|go:"GO:0032869"(cellular response to insulin stimulus)|go:"GO:0042802"(identical protein binding)|go:"GO:0045202"(synapse)|go:"GO:0045664"(regulation of neuron differentiation)|go:"GO:0048167"(regulation of synaptic plasticity)|go:"GO:0098793"(presynapse)|interpro:IPR000308(14-3-3 protein)|interpro:IPR023409|interpro:IPR023410|interpro:IPR036815|mint:P61983|reactome:R-RNO-111447|reactome:R-RNO-2565942|reactome:R-RNO-380259|reactome:R-RNO-380270|reactome:R-RNO-380284|reactome:R-RNO-380320|reactome:R-RNO-5620912|reactome:R-RNO-5625740|reactome:R-RNO-5628897|reactome:R-RNO-75035|reactome:R-RNO-8854518|reactome:R-RNO-9614399|refseq:XP_006249246.2	-	-	-	figure legend:st1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10116(rat-brain-cortex)|taxid:10116(Rattus norvegicus brain cortex)	-	2020/10/30	2020/10/30	rogid:DtE+ZXAZKdCMvUW5K+jXQ5bH07M10116	rogid:u1cd71h0RPgTOEMrQVhOelsxWnM10116	rigid:3wclwrjZRvafcOruQOYnegkn54c	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q5XIE8	uniprotkb:P12075	intact:EBI-15348306|ensembl:ENSRNOP00000023037	intact:EBI-26439500|ensembl:ENSRNOP00000022487	psi-mi:itm2b_rat(display_long)|uniprotkb:Itm2b(gene name)|psi-mi:Itm2b(display_short)|uniprotkb:Immature BRI2(gene name synonym)|uniprotkb:Transmembrane protein BRI(gene name synonym)	psi-mi:cox5b_rat(display_long)|uniprotkb:Cox5b(gene name)|psi-mi:Cox5b(display_short)|uniprotkb:Cytochrome c oxidase polypeptide Vb(gene name synonym)|uniprotkb:Cytochrome c oxidase subunit VIA*(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Martins et al. (2018)	imex:IM-28469|pubmed:29476059	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26439741|imex:IM-28469-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSRNOG00000016271(gene)|ensembl:ENSRNOT00000023037(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001540"(amyloid-beta binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0010008"(endosome membrane)|go:"GO:0030660"(Golgi-associated vesicle membrane)|go:"GO:0031301"(integral component of organelle membrane)|go:"GO:0042985"(negative regulation of amyloid precursor protein biosynthetic process)|interpro:IPR007084(BRICHOS)|interpro:IPR040145|mint:Q5XIE8|refseq:NP_001006964.1|rgd:620727	ensembl:ENSRNOG00000016660(gene)|ensembl:ENSRNOT00000022487(transcript)|go:"GO:0004129"(cytochrome-c oxidase activity)|go:"GO:0005739"(mitochondrion)|go:"GO:0005751"(mitochondrial respiratory chain complex IV)|go:"GO:0006123"(mitochondrial electron transport, cytochrome c to oxygen)|go:"GO:0009725"(response to hormone)|go:"GO:0043434"(response to peptide hormone)|go:"GO:0046872"(metal ion binding)|interpro:IPR002124(Cytochrome c oxidase, subunit Vb)|interpro:IPR020893|interpro:IPR036972|mint:P12075|reactome:R-RNO-5628897|reactome:R-RNO-611105|reactome:R-RNO-9707564|refseq:NP_446038.1|rgd:620608	-	-	-	figure legend:st1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10116(rat-brain-cortex)|taxid:10116(Rattus norvegicus brain cortex)	-	2020/10/30	2020/10/30	rogid:DtE+ZXAZKdCMvUW5K+jXQ5bH07M10116	rogid:6sI637xqMkBCynZU8PXYj77PfKQ10116	rigid:3wclwrjZRvafcOruQOYnegkn54c	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q5XIE8	uniprotkb:P31000	intact:EBI-15348306|ensembl:ENSRNOP00000023037	intact:EBI-368510	psi-mi:itm2b_rat(display_long)|uniprotkb:Itm2b(gene name)|psi-mi:Itm2b(display_short)|uniprotkb:Immature BRI2(gene name synonym)|uniprotkb:Transmembrane protein BRI(gene name synonym)	psi-mi:vime_rat(display_long)|uniprotkb:Vim(gene name)|psi-mi:Vim(display_short)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Martins et al. (2018)	imex:IM-28469|pubmed:29476059	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26439741|imex:IM-28469-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSRNOG00000016271(gene)|ensembl:ENSRNOT00000023037(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001540"(amyloid-beta binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0010008"(endosome membrane)|go:"GO:0030660"(Golgi-associated vesicle membrane)|go:"GO:0031301"(integral component of organelle membrane)|go:"GO:0042985"(negative regulation of amyloid precursor protein biosynthetic process)|interpro:IPR007084(BRICHOS)|interpro:IPR040145|mint:Q5XIE8|refseq:NP_001006964.1|rgd:620727	go:"GO:0044344"(cellular response to fibroblast growth factor stimulus)|go:"GO:0045098"(type III intermediate filament)|go:"GO:0045103"(intermediate filament-based process)|go:"GO:0045109"(intermediate filament organization)|go:"GO:0045335"(phagocytic vesicle)|go:"GO:0045444"(fat cell differentiation)|go:"GO:0045727"(positive regulation of translation)|go:"GO:0046697"(decidualization)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0050770"(regulation of axonogenesis)|go:"GO:0051721"(protein phosphatase 2A binding)|go:"GO:0060020"(Bergmann glial cell differentiation)|go:"GO:0060252"(positive regulation of glial cell proliferation)|go:"GO:0060395"(SMAD protein signal transduction)|go:"GO:0070307"(lens fiber cell development)|go:"GO:0071222"(cellular response to lipopolysaccharide)|go:"GO:0071225"(cellular response to muramyl dipeptide)|rgd:621646|refseq:NP_112402.1|go:"GO:0097110"(scaffold protein binding)|go:"GO:1900147"(regulation of Schwann cell migration)|go:"GO:1990254"(keratin filament binding)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR006821(Intermediate filament, DNA-binding region)|interpro:IPR018039|interpro:IPR027699|interpro:IPR039008|reactome:R-RNO-264870|reactome:R-RNO-390522|reactome:R-RNO-9013422|reactome:R-RNO-9646399|go:"GO:0071346"(cellular response to interferon-gamma)|go:"GO:0003723"(RNA binding)|go:"GO:0003725"(double-stranded RNA binding)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005200"(structural constituent of cytoskeleton)|go:"GO:0005212"(structural constituent of eye lens)|go:"GO:0005737"(cytoplasm)|go:"GO:0005777"(peroxisome)|go:"GO:0005829"(cytosol)|go:"GO:0005844"(polysome)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005882"(intermediate filament)|go:"GO:0005886"(plasma membrane)|go:"GO:0007568"(aging)|go:"GO:0009314"(response to radiation)|go:"GO:0010269"(response to selenium ion)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010977"(negative regulation of neuron projection development)|go:"GO:0014002"(astrocyte development)|go:"GO:0016363"(nuclear matrix)|go:"GO:0019900"(kinase binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030424"(axon)|go:"GO:0031252"(cell leading edge)|go:"GO:0032355"(response to estradiol)|go:"GO:0032967"(positive regulation of collagen biosynthetic process)|go:"GO:0033280"(response to vitamin D)|go:"GO:0042802"(identical protein binding)|go:"GO:0042995"(cell projection)|go:"GO:0043005"(neuron projection)|go:"GO:0043403"(skeletal muscle tissue regeneration)|go:"GO:0043488"(regulation of mRNA stability)|go:"GO:0044297"(cell body)|go:"GO:0010043"(response to zinc ion)|mint:P31000|dip:DIP-31882N	-	-	-	figure legend:st1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10116(rat-brain-cortex)|taxid:10116(Rattus norvegicus brain cortex)	-	2020/10/30	2020/10/30	rogid:DtE+ZXAZKdCMvUW5K+jXQ5bH07M10116	rogid:gXqxWYjgPhNbQNfJNwdt/Q4D4u010116	rigid:3wclwrjZRvafcOruQOYnegkn54c	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q5XIE8	uniprotkb:P70566	intact:EBI-15348306|ensembl:ENSRNOP00000023037	intact:EBI-16221588|ensembl:ENSRNOP00000014124	psi-mi:itm2b_rat(display_long)|uniprotkb:Itm2b(gene name)|psi-mi:Itm2b(display_short)|uniprotkb:Immature BRI2(gene name synonym)|uniprotkb:Transmembrane protein BRI(gene name synonym)	psi-mi:tmod2_rat(display_long)|uniprotkb:Tmod2(gene name)|psi-mi:Tmod2(display_short)|uniprotkb:Ntmod(gene name synonym)|uniprotkb:Neuronal tropomodulin(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Martins et al. (2018)	imex:IM-28469|pubmed:29476059	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26439741|imex:IM-28469-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSRNOG00000016271(gene)|ensembl:ENSRNOT00000023037(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001540"(amyloid-beta binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0010008"(endosome membrane)|go:"GO:0030660"(Golgi-associated vesicle membrane)|go:"GO:0031301"(integral component of organelle membrane)|go:"GO:0042985"(negative regulation of amyloid precursor protein biosynthetic process)|interpro:IPR007084(BRICHOS)|interpro:IPR040145|mint:Q5XIE8|refseq:NP_001006964.1|rgd:620727	ensembl:ENSRNOG00000010447(gene)|ensembl:ENSRNOT00000014124(transcript)|go:"GO:0003779"(actin binding)|go:"GO:0005523"(tropomyosin binding)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005865"(striated muscle thin filament)|go:"GO:0006936"(muscle contraction)|go:"GO:0007015"(actin filament organization)|go:"GO:0007270"(neuron-neuron synaptic transmission)|go:"GO:0007611"(learning or memory)|go:"GO:0030016"(myofibril)|go:"GO:0030239"(myofibril assembly)|go:"GO:0030426"(growth cone)|go:"GO:0043005"(neuron projection)|go:"GO:0045202"(synapse)|go:"GO:0045745"(positive regulation of G protein-coupled receptor signaling pathway)|go:"GO:0051694"(pointed-end actin filament capping)|interpro:IPR004934(Tropomodulin)|interpro:IPR030130|interpro:IPR032675|mint:P70566|reactome:R-RNO-390522|rgd:61948|refseq:NP_113801.1|refseq:XP_006243469.1|refseq:XP_006243470.1|refseq:XP_008764553.1|refseq:XP_017451363.1	-	-	-	figure legend:st1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10116(rat-brain-cortex)|taxid:10116(Rattus norvegicus brain cortex)	-	2020/10/30	2020/10/30	rogid:DtE+ZXAZKdCMvUW5K+jXQ5bH07M10116	rogid:NZcqpDi6faan3J/6MGaDvpwkfX810116	rigid:3wclwrjZRvafcOruQOYnegkn54c	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q5XIE8	uniprotkb:P97610	intact:EBI-15348306|ensembl:ENSRNOP00000023037	intact:EBI-26437627|ensembl:ENSRNOP00000026153	psi-mi:itm2b_rat(display_long)|uniprotkb:Itm2b(gene name)|psi-mi:Itm2b(display_short)|uniprotkb:Immature BRI2(gene name synonym)|uniprotkb:Transmembrane protein BRI(gene name synonym)	psi-mi:syt12_rat(display_long)|uniprotkb:Syt12(gene name)|psi-mi:Syt12(display_short)|uniprotkb:Srg1(gene name synonym)|uniprotkb:Sytr1(gene name synonym)|uniprotkb:Synaptotagmin XII(gene name synonym)|uniprotkb:Synaptotagmin-related gene 1 protein(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Martins et al. (2018)	imex:IM-28469|pubmed:29476059	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26439741|imex:IM-28469-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSRNOG00000016271(gene)|ensembl:ENSRNOT00000023037(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001540"(amyloid-beta binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0010008"(endosome membrane)|go:"GO:0030660"(Golgi-associated vesicle membrane)|go:"GO:0031301"(integral component of organelle membrane)|go:"GO:0042985"(negative regulation of amyloid precursor protein biosynthetic process)|interpro:IPR007084(BRICHOS)|interpro:IPR040145|mint:Q5XIE8|refseq:NP_001006964.1|rgd:620727	ensembl:ENSRNOG00000019306(gene)|ensembl:ENSRNOT00000026152(transcript)|go:"GO:0000149"(SNARE binding)|go:"GO:0001786"(phosphatidylserine binding)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005544"(calcium-dependent phospholipid binding)|go:"GO:0005886"(plasma membrane)|go:"GO:0014059"(regulation of dopamine secretion)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016192"(vesicle-mediated transport)|go:"GO:0017156"(calcium-ion regulated exocytosis)|go:"GO:0017158"(regulation of calcium ion-dependent exocytosis)|go:"GO:0019905"(syntaxin binding)|go:"GO:0030276"(clathrin binding)|go:"GO:0030672"(synaptic vesicle membrane)|go:"GO:0046928"(regulation of neurotransmitter secretion)|go:"GO:0048792"(spontaneous exocytosis of neurotransmitter)|go:"GO:0060291"(long-term synaptic potentiation)|go:"GO:0070382"(exocytic vesicle)|go:"GO:0071277"(cellular response to calcium ion)|go:"GO:0098686"(hippocampal mossy fiber to CA3 synapse)|go:"GO:0098793"(presynapse)|interpro:IPR000008(C2 calcium-dependent membrane targeting)|interpro:IPR030537|interpro:IPR035892|mint:P97610|refseq:NP_620190.1|rgd:621876	-	-	-	figure legend:st1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10116(rat-brain-cortex)|taxid:10116(Rattus norvegicus brain cortex)	-	2020/10/30	2020/10/30	rogid:DtE+ZXAZKdCMvUW5K+jXQ5bH07M10116	rogid:J1OnAWaV8g9oWmhRGOxK8VddyJs10116	rigid:3wclwrjZRvafcOruQOYnegkn54c	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q5XIE8	uniprotkb:Q62876	intact:EBI-15348306|ensembl:ENSRNOP00000023037	intact:EBI-15349536|ensembl:ENSRNOP00000023066	psi-mi:itm2b_rat(display_long)|uniprotkb:Itm2b(gene name)|psi-mi:Itm2b(display_short)|uniprotkb:Immature BRI2(gene name synonym)|uniprotkb:Transmembrane protein BRI(gene name synonym)	psi-mi:sng1_rat(display_long)|uniprotkb:Syngr1(gene name)|psi-mi:Syngr1(display_short)|uniprotkb:p29(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Martins et al. (2018)	imex:IM-28469|pubmed:29476059	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26439741|imex:IM-28469-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSRNOG00000016271(gene)|ensembl:ENSRNOT00000023037(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001540"(amyloid-beta binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0010008"(endosome membrane)|go:"GO:0030660"(Golgi-associated vesicle membrane)|go:"GO:0031301"(integral component of organelle membrane)|go:"GO:0042985"(negative regulation of amyloid precursor protein biosynthetic process)|interpro:IPR007084(BRICHOS)|interpro:IPR040145|mint:Q5XIE8|refseq:NP_001006964.1|rgd:620727	ensembl:ENSRNOT00000023066(transcript)|go:"GO:0006605"(protein targeting)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0030285"(integral component of synaptic vesicle membrane)|go:"GO:0030672"(synaptic vesicle membrane)|go:"GO:0031594"(neuromuscular junction)|go:"GO:0042470"(melanosome)|go:"GO:0043195"(terminal bouton)|go:"GO:0045055"(regulated exocytosis)|go:"GO:0048169"(regulation of long-term neuronal synaptic plasticity)|ensembl:ENSRNOG00000017108(gene)|go:"GO:0048172"(regulation of short-term neuronal synaptic plasticity)|go:"GO:0048499"(synaptic vesicle membrane organization)|go:"GO:1990830"(cellular response to leukemia inhibitory factor)|interpro:IPR008253(Marvel)|interpro:IPR016579(Synaptogyrin)|mint:Q62876|reactome:R-RNO-6798695|rgd:3801|refseq:NP_062039.1	-	-	-	figure legend:st1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10116(rat-brain-cortex)|taxid:10116(Rattus norvegicus brain cortex)	-	2020/10/30	2020/10/30	rogid:DtE+ZXAZKdCMvUW5K+jXQ5bH07M10116	rogid:BLWDXZqURmVydl4j/e8DPDiiuK010116	rigid:3wclwrjZRvafcOruQOYnegkn54c	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q5XIE8	uniprotkb:Q9QWN8	intact:EBI-15348306|ensembl:ENSRNOP00000023037	intact:EBI-26373337|uniprotkb:O88197|uniprotkb:Q9ES68	psi-mi:itm2b_rat(display_long)|uniprotkb:Itm2b(gene name)|psi-mi:Itm2b(display_short)|uniprotkb:Immature BRI2(gene name synonym)|uniprotkb:Transmembrane protein BRI(gene name synonym)	psi-mi:sptn2_rat(display_long)|uniprotkb:Beta SpIII sigma 1(gene name synonym)|uniprotkb:Beta-III spectrin(gene name synonym)|uniprotkb:Glutamate transporter EAAT4-associated protein 41(gene name synonym)|uniprotkb:SPNB-3(gene name synonym)|uniprotkb:Spectrin-like protein GTRAP41(gene name synonym)|uniprotkb:Sptbn2(gene name)|psi-mi:Sptbn2(display_short)|uniprotkb:Spnb3(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Martins et al. (2018)	imex:IM-28469|pubmed:29476059	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26439741|imex:IM-28469-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSRNOG00000016271(gene)|ensembl:ENSRNOT00000023037(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001540"(amyloid-beta binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0010008"(endosome membrane)|go:"GO:0030660"(Golgi-associated vesicle membrane)|go:"GO:0031301"(integral component of organelle membrane)|go:"GO:0042985"(negative regulation of amyloid precursor protein biosynthetic process)|interpro:IPR007084(BRICHOS)|interpro:IPR040145|mint:Q5XIE8|refseq:NP_001006964.1|rgd:620727	go:"GO:0000139"(Golgi membrane)|go:"GO:0003779"(actin binding)|go:"GO:0005200"(structural constituent of cytoskeleton)|go:"GO:0005543"(phospholipid binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0007416"(synapse assembly)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0008091"(spectrin)|go:"GO:0016079"(synaptic vesicle exocytosis)|go:"GO:0016081"(synaptic vesicle docking)|go:"GO:0016192"(vesicle-mediated transport)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0016363"(nuclear matrix)|go:"GO:0017158"(regulation of calcium ion-dependent exocytosis)|go:"GO:0021692"(cerebellar Purkinje cell layer morphogenesis)|go:"GO:0030534"(adult behavior)|go:"GO:0035264"(multicellular organism growth)|go:"GO:0043025"(neuronal cell body)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051693"(actin filament capping)|go:"GO:0071361"(cellular response to ethanol)|go:"GO:0098688"(parallel fiber to Purkinje cell synapse)|go:"GO:0098793"(presynapse)|go:"GO:0098918"(structural constituent of synapse)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099173"(postsynapse organization)|go:"GO:0099189"(postsynaptic spectrin-associated cytoskeleton)|reactome:R-RNO-2132295|reactome:R-RNO-375165|reactome:R-RNO-445095|reactome:R-RNO-5673001|reactome:R-RNO-6807878|rgd:3751|mint:Q9QWN8|interpro:IPR001589(Actinin-type, actin-binding, conserved site)|interpro:IPR001715(Calponin-like actin-binding)|interpro:IPR036872|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR041681|interpro:IPR001605(Spectrin/pleckstrin-like)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR018159|interpro:IPR016343(Spectrin, beta subunit)|interpro:IPR002017(Spectrin repeat)	-	-	-	figure legend:st1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10116(rat-brain-cortex)|taxid:10116(Rattus norvegicus brain cortex)	-	2020/10/30	2020/10/30	rogid:DtE+ZXAZKdCMvUW5K+jXQ5bH07M10116	rogid:mYeNz7x0BsYG5aS/meqBSkzcX0M10116	rigid:3wclwrjZRvafcOruQOYnegkn54c	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q5XIE8	uniprotkb:Q9JHY2	intact:EBI-15348306|ensembl:ENSRNOP00000023037	intact:EBI-919945	psi-mi:itm2b_rat(display_long)|uniprotkb:Itm2b(gene name)|psi-mi:Itm2b(display_short)|uniprotkb:Immature BRI2(gene name synonym)|uniprotkb:Transmembrane protein BRI(gene name synonym)	psi-mi:sfxn3_rat(display_long)|uniprotkb:Sfxn3(gene name)|psi-mi:Sfxn3(display_short)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Martins et al. (2018)	imex:IM-28469|pubmed:29476059	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26439741|imex:IM-28469-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSRNOG00000016271(gene)|ensembl:ENSRNOT00000023037(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001540"(amyloid-beta binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0010008"(endosome membrane)|go:"GO:0030660"(Golgi-associated vesicle membrane)|go:"GO:0031301"(integral component of organelle membrane)|go:"GO:0042985"(negative regulation of amyloid precursor protein biosynthetic process)|interpro:IPR007084(BRICHOS)|interpro:IPR040145|mint:Q5XIE8|refseq:NP_001006964.1|rgd:620727	rgd:620716|refseq:NP_075237.1|interpro:IPR004686(Tricarboxylate/iron carrier)|mint:Q9JHY2|go:"GO:0005371"(tricarboxylate secondary active transmembrane transporter activity)|go:"GO:0005739"(mitochondrion)|go:"GO:0006730"(one-carbon metabolic process)|go:"GO:0022857"(transmembrane transporter activity)|go:"GO:0022889"(serine transmembrane transporter activity)|go:"GO:0031305"(integral component of mitochondrial inner membrane)|go:"GO:0031966"(mitochondrial membrane)|go:"GO:0140300"(serine import into mitochondrion)|go:"GO:1990542"(mitochondrial transmembrane transport)	-	-	-	figure legend:st1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10116(rat-brain-cortex)|taxid:10116(Rattus norvegicus brain cortex)	-	2020/10/30	2020/10/30	rogid:DtE+ZXAZKdCMvUW5K+jXQ5bH07M10116	rogid:KXWPONNXXrT71ucMJjKuHe6V+EE10116	rigid:3wclwrjZRvafcOruQOYnegkn54c	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q5XIE8	uniprotkb:B3GNI6	intact:EBI-15348306|ensembl:ENSRNOP00000023037	intact:EBI-2009404|uniprotkb:B3DMA8|uniprotkb:B3GNI4	psi-mi:itm2b_rat(display_long)|uniprotkb:Itm2b(gene name)|psi-mi:Itm2b(display_short)|uniprotkb:Immature BRI2(gene name synonym)|uniprotkb:Transmembrane protein BRI(gene name synonym)	psi-mi:sep11_rat(display_long)|uniprotkb:Septin11(gene name)|psi-mi:Septin11(display_short)|uniprotkb:Sept11(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Martins et al. (2018)	imex:IM-28469|pubmed:29476059	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26439741|imex:IM-28469-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSRNOG00000016271(gene)|ensembl:ENSRNOT00000023037(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001540"(amyloid-beta binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0010008"(endosome membrane)|go:"GO:0030660"(Golgi-associated vesicle membrane)|go:"GO:0031301"(integral component of organelle membrane)|go:"GO:0042985"(negative regulation of amyloid precursor protein biosynthetic process)|interpro:IPR007084(BRICHOS)|interpro:IPR040145|mint:Q5XIE8|refseq:NP_001006964.1|rgd:620727	interpro:IPR030379|rgd:1307405|refseq:NP_001100678.1|interpro:IPR016491(Septin)|mint:B3GNI6|interpro:IPR027417|go:"GO:0001725"(stress fiber)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005940"(septin ring)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0030424"(axon)|go:"GO:0031105"(septin complex)|go:"GO:0032153"(cell division site)|go:"GO:0034613"(cellular protein localization)|go:"GO:0043197"(dendritic spine)|go:"GO:0050807"(regulation of synapse organization)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0061640"(cytoskeleton-dependent cytokinesis)|go:"GO:0098794"(postsynapse)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0098982"(GABA-ergic synapse)|go:"GO:0099629"(postsynaptic specialization of symmetric synapse)	-	-	-	figure legend:st1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10116(rat-brain-cortex)|taxid:10116(Rattus norvegicus brain cortex)	-	2020/10/30	2020/10/30	rogid:DtE+ZXAZKdCMvUW5K+jXQ5bH07M10116	rogid:RfdukqyhC/1qeJHPQmrz7ryDmdY10116	rigid:3wclwrjZRvafcOruQOYnegkn54c	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q5XIE8	uniprotkb:D4AE41	intact:EBI-15348306|ensembl:ENSRNOP00000023037	intact:EBI-22237303	psi-mi:itm2b_rat(display_long)|uniprotkb:Itm2b(gene name)|psi-mi:Itm2b(display_short)|uniprotkb:Immature BRI2(gene name synonym)|uniprotkb:Transmembrane protein BRI(gene name synonym)	psi-mi:rmxl1_rat(display_long)|uniprotkb:Heterogeneous nuclear ribonucleoprotein G-like 1(gene name synonym)|uniprotkb:Rbmxl1(gene name)|psi-mi:Rbmxl1(display_short)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Martins et al. (2018)	imex:IM-28469|pubmed:29476059	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26439741|imex:IM-28469-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSRNOG00000016271(gene)|ensembl:ENSRNOT00000023037(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001540"(amyloid-beta binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0010008"(endosome membrane)|go:"GO:0030660"(Golgi-associated vesicle membrane)|go:"GO:0031301"(integral component of organelle membrane)|go:"GO:0042985"(negative regulation of amyloid precursor protein biosynthetic process)|interpro:IPR007084(BRICHOS)|interpro:IPR040145|mint:Q5XIE8|refseq:NP_001006964.1|rgd:620727	go:"GO:0003723"(RNA binding)|go:"GO:0005681"(spliceosomal complex)|go:"GO:0006397"(mRNA processing)|go:"GO:0008380"(RNA splicing)|go:"GO:0048026"(positive regulation of mRNA splicing, via spliceosome)|mint:D4AE41|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR035979|interpro:IPR012604(RBM1CTR)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR003954(RNA recognition, region 1)|rgd:1585845	-	-	-	figure legend:st1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10116(rat-brain-cortex)|taxid:10116(Rattus norvegicus brain cortex)	-	2020/10/30	2020/10/30	rogid:DtE+ZXAZKdCMvUW5K+jXQ5bH07M10116	rogid:ozGuiB8V5solV2Fy6BBUnRL0S6U10116	rigid:3wclwrjZRvafcOruQOYnegkn54c	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q5XIE8	uniprotkb:Q6NYB7	intact:EBI-15348306|ensembl:ENSRNOP00000023037	intact:EBI-918913|uniprotkb:P05711|ensembl:ENSRNOP00000073493	psi-mi:itm2b_rat(display_long)|uniprotkb:Itm2b(gene name)|psi-mi:Itm2b(display_short)|uniprotkb:Immature BRI2(gene name synonym)|uniprotkb:Transmembrane protein BRI(gene name synonym)	psi-mi:rab1a_rat(display_long)|uniprotkb:Rab1A(gene name)|psi-mi:Rab1A(display_short)|uniprotkb:Rab1(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Martins et al. (2018)	imex:IM-28469|pubmed:29476059	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26439741|imex:IM-28469-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSRNOG00000016271(gene)|ensembl:ENSRNOT00000023037(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001540"(amyloid-beta binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0010008"(endosome membrane)|go:"GO:0030660"(Golgi-associated vesicle membrane)|go:"GO:0031301"(integral component of organelle membrane)|go:"GO:0042985"(negative regulation of amyloid precursor protein biosynthetic process)|interpro:IPR007084(BRICHOS)|interpro:IPR040145|mint:Q5XIE8|refseq:NP_001006964.1|rgd:620727	rgd:619736|refseq:NP_112352.2|ensembl:ENSRNOG00000004992(gene)|ensembl:ENSRNOT00000084481(transcript)|go:"GO:0000045"(autophagosome assembly)|go:"GO:0000139"(Golgi membrane)|go:"GO:0003924"(GTPase activity)|go:"GO:0003925"(G protein activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005769"(early endosome)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0006897"(endocytosis)|go:"GO:0006914"(autophagy)|go:"GO:0007030"(Golgi organization)|go:"GO:0012505"(endomembrane system)|go:"GO:0016477"(cell migration)|go:"GO:0019068"(virion assembly)|go:"GO:0030252"(growth hormone secretion)|go:"GO:0032402"(melanosome transport)|go:"GO:0032482"(Rab protein signal transduction)|go:"GO:0032757"(positive regulation of interleukin-8 production)|go:"GO:0034446"(substrate adhesion-dependent cell spreading)|go:"GO:0042470"(melanosome)|go:"GO:0042742"(defense response to bacterium)|go:"GO:0043025"(neuronal cell body)|go:"GO:0047496"(vesicle transport along microtubule)|go:"GO:0090110"(COPII-coated vesicle cargo loading)|go:"GO:0098793"(presynapse)|go:"GO:1903020"(positive regulation of glycoprotein metabolic process)|interpro:IPR001806(Ras GTPase)|interpro:IPR005225(Small GTP-binding protein)|interpro:IPR027417|mint:Q6NYB7|reactome:R-RNO-162658|reactome:R-RNO-204005|reactome:R-RNO-6807878|reactome:R-RNO-6811434|reactome:R-RNO-8873719|reactome:R-RNO-8876198	-	-	-	figure legend:st1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10116(rat-brain-cortex)|taxid:10116(Rattus norvegicus brain cortex)	-	2020/10/30	2020/10/30	rogid:DtE+ZXAZKdCMvUW5K+jXQ5bH07M10116	rogid:Pa9NYKiCNXtxRwthh1r/pGbZyf010116	rigid:3wclwrjZRvafcOruQOYnegkn54c	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q5XIE8	uniprotkb:P61107	intact:EBI-15348306|ensembl:ENSRNOP00000023037	intact:EBI-917845|uniprotkb:P35287|uniprotkb:Q969L0|uniprotkb:Q9UI11	psi-mi:itm2b_rat(display_long)|uniprotkb:Itm2b(gene name)|psi-mi:Itm2b(display_short)|uniprotkb:Immature BRI2(gene name synonym)|uniprotkb:Transmembrane protein BRI(gene name synonym)	psi-mi:rab14_rat(display_long)|uniprotkb:Rab14(gene name)|psi-mi:Rab14(display_short)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Martins et al. (2018)	imex:IM-28469|pubmed:29476059	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26439741|imex:IM-28469-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSRNOG00000016271(gene)|ensembl:ENSRNOT00000023037(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001540"(amyloid-beta binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0010008"(endosome membrane)|go:"GO:0030660"(Golgi-associated vesicle membrane)|go:"GO:0031301"(integral component of organelle membrane)|go:"GO:0042985"(negative regulation of amyloid precursor protein biosynthetic process)|interpro:IPR007084(BRICHOS)|interpro:IPR040145|mint:Q5XIE8|refseq:NP_001006964.1|rgd:620727	rgd:620881|refseq:NP_446041.1|interpro:IPR005225(Small GTP-binding protein)|interpro:IPR001806(Ras GTPase)|interpro:IPR030702|interpro:IPR027417|mint:P61107|go:"GO:0000139"(Golgi membrane)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005764"(lysosome)|go:"GO:0005769"(early endosome)|go:"GO:0005770"(late endosome)|go:"GO:0005791"(rough endoplasmic reticulum)|go:"GO:0005795"(Golgi stack)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006895"(Golgi to endosome transport)|go:"GO:0007589"(body fluid secretion)|go:"GO:0008543"(fibroblast growth factor receptor signaling pathway)|go:"GO:0012505"(endomembrane system)|go:"GO:0016192"(vesicle-mediated transport)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0019003"(GDP binding)|go:"GO:0030133"(transport vesicle)|go:"GO:0030140"(trans-Golgi network transport vesicle)|go:"GO:0030659"(cytoplasmic vesicle membrane)|go:"GO:0031489"(myosin V binding)|go:"GO:0031901"(early endosome membrane)|go:"GO:0032456"(endocytic recycling)|go:"GO:0032880"(regulation of protein localization)|go:"GO:0042175"(nuclear outer membrane-endoplasmic reticulum membrane network)|go:"GO:0042742"(defense response to bacterium)|go:"GO:0045176"(apical protein localization)|go:"GO:0045335"(phagocytic vesicle)|go:"GO:0045995"(regulation of embryonic development)|go:"GO:0046907"(intracellular transport)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0055037"(recycling endosome)|go:"GO:0090387"(phagolysosome assembly involved in apoptotic cell clearance)|go:"GO:0097208"(alveolar lamellar body)|go:"GO:0098993"(anchored component of synaptic vesicle membrane)|reactome:R-RNO-1660499|reactome:R-RNO-6798695|reactome:R-RNO-8873719|reactome:R-RNO-8876198	-	-	-	figure legend:st1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10116(rat-brain-cortex)|taxid:10116(Rattus norvegicus brain cortex)	-	2020/10/30	2020/10/30	rogid:DtE+ZXAZKdCMvUW5K+jXQ5bH07M10116	rogid:KPCWiyc6plQCbqAnsREsHrR61LM10116	rigid:3wclwrjZRvafcOruQOYnegkn54c	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q5XIE8	uniprotkb:Q6RUV5	intact:EBI-15348306|ensembl:ENSRNOP00000023037	intact:EBI-919251|ensembl:ENSRNOP00000001417	psi-mi:itm2b_rat(display_long)|uniprotkb:Itm2b(gene name)|psi-mi:Itm2b(display_short)|uniprotkb:Immature BRI2(gene name synonym)|uniprotkb:Transmembrane protein BRI(gene name synonym)	psi-mi:rac1_rat(display_long)|uniprotkb:Rac1(gene name)|psi-mi:Rac1(display_short)|uniprotkb:p21-Rac1(gene name synonym)|uniprotkb:Rac(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Martins et al. (2018)	imex:IM-28469|pubmed:29476059	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26439741|imex:IM-28469-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSRNOG00000016271(gene)|ensembl:ENSRNOT00000023037(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001540"(amyloid-beta binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0010008"(endosome membrane)|go:"GO:0030660"(Golgi-associated vesicle membrane)|go:"GO:0031301"(integral component of organelle membrane)|go:"GO:0042985"(negative regulation of amyloid precursor protein biosynthetic process)|interpro:IPR007084(BRICHOS)|interpro:IPR040145|mint:Q5XIE8|refseq:NP_001006964.1|rgd:620727	rgd:619755|refseq:NP_599193.1|dip:DIP-37114N|ensembl:ENSRNOG00000001068(gene)|ensembl:ENSRNOT00000001417(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0000242"(pericentriolar material)|go:"GO:0001764"(neuron migration)|go:"GO:0001891"(phagocytic cup)|go:"GO:0001934"(positive regulation of protein phosphorylation)|go:"GO:0002093"(auditory receptor cell morphogenesis)|go:"GO:0002551"(mast cell chemotaxis)|go:"GO:0003376"(sphingosine-1-phosphate receptor signaling pathway)|go:"GO:0003382"(epithelial cell morphogenesis)|go:"GO:0003924"(GTPase activity)|go:"GO:0003925"(G protein activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005884"(actin filament)|go:"GO:0005886"(plasma membrane)|go:"GO:0005938"(cell cortex)|go:"GO:0006897"(endocytosis)|go:"GO:0006911"(phagocytosis, engulfment)|go:"GO:0006935"(chemotaxis)|go:"GO:0006972"(hyperosmotic response)|go:"GO:0007010"(cytoskeleton organization)|go:"GO:0007015"(actin filament organization)|go:"GO:0007155"(cell adhesion)|go:"GO:0007163"(establishment or maintenance of cell polarity)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0007264"(small GTPase mediated signal transduction)|go:"GO:0007411"(axon guidance)|go:"GO:0008045"(motor neuron axon guidance)|go:"GO:0008283"(cell population proliferation)|go:"GO:0008360"(regulation of cell shape)|go:"GO:0008361"(regulation of cell size)|go:"GO:0010591"(regulation of lamellipodium assembly)|go:"GO:0010592"(positive regulation of lamellipodium assembly)|go:"GO:0010595"(positive regulation of endothelial cell migration)|go:"GO:0010762"(regulation of fibroblast migration)|go:"GO:0010764"(negative regulation of fibroblast migration)|go:"GO:0010811"(positive regulation of cell-substrate adhesion)|go:"GO:0014041"(regulation of neuron maturation)|go:"GO:0016020"(membrane)|go:"GO:0016358"(dendrite development)|go:"GO:0016477"(cell migration)|go:"GO:0016601"(Rac protein signal transduction)|go:"GO:0019897"(extrinsic component of plasma membrane)|go:"GO:0019899"(enzyme binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0021799"(cerebral cortex radially oriented cell migration)|go:"GO:0021831"(embryonic olfactory bulb interneuron precursor migration)|go:"GO:0021894"(cerebral cortex GABAergic interneuron development)|go:"GO:0022604"(regulation of cell morphogenesis)|go:"GO:0030027"(lamellipodium)|go:"GO:0030031"(cell projection assembly)|go:"GO:0030032"(lamellipodium assembly)|go:"GO:0030036"(actin cytoskeleton organization)|go:"GO:0030041"(actin filament polymerization)|go:"GO:0030334"(regulation of cell migration)|go:"GO:0030742"(GTP-dependent protein binding)|go:"GO:0030838"(positive regulation of actin filament polymerization)|go:"GO:0030865"(cortical cytoskeleton organization)|go:"GO:0030900"(forebrain development)|go:"GO:0031116"(positive regulation of microtubule polymerization)|go:"GO:0031234"(extrinsic component of cytoplasmic side of plasma membrane)|go:"GO:0031267"(small GTPase binding)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0031529"(ruffle organization)|go:"GO:0031901"(early endosome membrane)|go:"GO:0031996"(thioesterase binding)|go:"GO:0032587"(ruffle membrane)|go:"GO:0032707"(negative regulation of interleukin-23 production)|go:"GO:0032956"(regulation of actin cytoskeleton organization)|go:"GO:0034446"(substrate adhesion-dependent cell spreading)|go:"GO:0035567"(non-canonical Wnt signaling pathway)|go:"GO:0035774"(positive regulation of insulin secretion involved in cellular response to glucose stimulus)|go:"GO:0036464"(cytoplasmic ribonucleoprotein granule)|go:"GO:0042470"(melanosome)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0042995"(cell projection)|go:"GO:0043197"(dendritic spine)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0043552"(positive regulation of phosphatidylinositol 3-kinase activity)|go:"GO:0043652"(engulfment of apoptotic cell)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045216"(cell-cell junction organization)|go:"GO:0045428"(regulation of nitric oxide biosynthetic process)|go:"GO:0045453"(bone resorption)|go:"GO:0045740"(positive regulation of DNA replication)|go:"GO:0046425"(regulation of receptor signaling pathway via JAK-STAT)|go:"GO:0048012"(hepatocyte growth factor receptor signaling pathway)|go:"GO:0048168"(regulation of neuronal synaptic plasticity)|go:"GO:0048532"(anatomical structure arrangement)|go:"GO:0048812"(neuron projection morphogenesis)|go:"GO:0048813"(dendrite morphogenesis)|go:"GO:0048870"(cell motility)|go:"GO:0048873"(homeostasis of number of cells within a tissue)|go:"GO:0051022"(Rho GDP-dissociation inhibitor binding)|go:"GO:0051117"(ATPase binding)|go:"GO:0051492"(regulation of stress fiber assembly)|go:"GO:0051496"(positive regulation of stress fiber assembly)|go:"GO:0051668"(localization within membrane)|go:"GO:0051894"(positive regulation of focal adhesion assembly)|go:"GO:0051932"(synaptic transmission, GABAergic)|go:"GO:0055038"(recycling endosome membrane)|go:"GO:0060071"(Wnt signaling pathway, planar cell polarity pathway)|go:"GO:0060091"(kinocilium)|go:"GO:0060263"(regulation of respiratory burst)|go:"GO:0060999"(positive regulation of dendritic spine development)|go:"GO:0061344"(regulation of cell adhesion involved in heart morphogenesis)|go:"GO:0071260"(cellular response to mechanical stimulus)|go:"GO:0071526"(semaphorin-plexin signaling pathway)|go:"GO:0071542"(dopaminergic neuron differentiation)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0090023"(positive regulation of neutrophil chemotaxis)|go:"GO:0090103"(cochlea morphogenesis)|go:"GO:0097178"(ruffle assembly)|go:"GO:0098794"(postsynapse)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:1900026"(positive regulation of substrate adhesion-dependent cell spreading)|go:"GO:1902622"(regulation of neutrophil migration)|go:"GO:1904948"(midbrain dopaminergic neuron differentiation)|go:"GO:2000386"(positive regulation of ovarian follicle development)|interpro:IPR001806(Ras GTPase)|interpro:IPR003578(Ras small GTPase, Rho type)|interpro:IPR005225(Small GTP-binding protein)|interpro:IPR027417|mint:Q6RUV5|reactome:R-RNO-114604|reactome:R-RNO-1257604|reactome:R-RNO-1433557|reactome:R-RNO-193648|reactome:R-RNO-2029482|reactome:R-RNO-2424491|reactome:R-RNO-2871796|reactome:R-RNO-376172|reactome:R-RNO-389359|reactome:R-RNO-3928662|reactome:R-RNO-3928664|reactome:R-RNO-3928665|reactome:R-RNO-399954|reactome:R-RNO-4086400|reactome:R-RNO-416550|reactome:R-RNO-418885|reactome:R-RNO-4420097|reactome:R-RNO-445144|reactome:R-RNO-5218920|reactome:R-RNO-5625740|reactome:R-RNO-5625900|reactome:R-RNO-5625970|reactome:R-RNO-5626467|reactome:R-RNO-5627123|reactome:R-RNO-5663213|reactome:R-RNO-5663220|reactome:R-RNO-5668599|reactome:R-RNO-5687128|reactome:R-RNO-6798695|reactome:R-RNO-6811558|reactome:R-RNO-8849471|reactome:R-RNO-8875555|reactome:R-RNO-9013149|reactome:R-RNO-9032759|reactome:R-RNO-983231	-	-	-	figure legend:st1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10116(rat-brain-cortex)|taxid:10116(Rattus norvegicus brain cortex)	-	2020/10/30	2020/10/30	rogid:DtE+ZXAZKdCMvUW5K+jXQ5bH07M10116	rogid:8rkYyZSFL5tIfbRNKZgP/UDxD+A10116	rigid:3wclwrjZRvafcOruQOYnegkn54c	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q5XIE8	uniprotkb:O88778	intact:EBI-15348306|ensembl:ENSRNOP00000023037	intact:EBI-2271660	psi-mi:itm2b_rat(display_long)|uniprotkb:Itm2b(gene name)|psi-mi:Itm2b(display_short)|uniprotkb:Immature BRI2(gene name synonym)|uniprotkb:Transmembrane protein BRI(gene name synonym)	psi-mi:bsn_rat(display_long)|uniprotkb:Bsn(gene name)|psi-mi:Bsn(display_short)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Martins et al. (2018)	imex:IM-28469|pubmed:29476059	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26439741|imex:IM-28469-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSRNOG00000016271(gene)|ensembl:ENSRNOT00000023037(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001540"(amyloid-beta binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0010008"(endosome membrane)|go:"GO:0030660"(Golgi-associated vesicle membrane)|go:"GO:0031301"(integral component of organelle membrane)|go:"GO:0042985"(negative regulation of amyloid precursor protein biosynthetic process)|interpro:IPR007084(BRICHOS)|interpro:IPR040145|mint:Q5XIE8|refseq:NP_001006964.1|rgd:620727	rgd:2223|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|interpro:IPR008899(Zinc finger, piccolo-type)|interpro:IPR030627|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|mint:O88778|go:"GO:0001222"(transcription corepressor binding)|go:"GO:0005798"(Golgi-associated vesicle)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0007010"(cytoskeleton organization)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0008088"(axo-dendritic transport)|go:"GO:0008090"(retrograde axonal transport)|go:"GO:0009986"(cell surface)|go:"GO:0014069"(postsynaptic density)|go:"GO:0019898"(extrinsic component of membrane)|go:"GO:0030424"(axon)|go:"GO:0030425"(dendrite)|go:"GO:0030672"(synaptic vesicle membrane)|go:"GO:0035418"(protein localization to synapse)|go:"GO:0043025"(neuronal cell body)|go:"GO:0044306"(neuron projection terminus)|go:"GO:0045202"(synapse)|go:"GO:0045503"(dynein light chain binding)|go:"GO:0046872"(metal ion binding)|go:"GO:0048786"(presynaptic active zone)|go:"GO:0048788"(cytoskeleton of presynaptic active zone)|go:"GO:0050808"(synapse organization)|go:"GO:0060076"(excitatory synapse)|go:"GO:0060077"(inhibitory synapse)|go:"GO:0097470"(ribbon synapse)|go:"GO:0098685"(Schaffer collateral - CA1 synapse)|go:"GO:0098686"(hippocampal mossy fiber to CA3 synapse)|go:"GO:0098693"(regulation of synaptic vesicle cycle)|go:"GO:0098793"(presynapse)|go:"GO:0098831"(presynaptic active zone cytoplasmic component)|go:"GO:0098882"(structural constituent of presynaptic active zone)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0098982"(GABA-ergic synapse)|go:"GO:0099526"(presynapse to nucleus signaling pathway)|go:"GO:1904071"(presynaptic active zone assembly)|go:"GO:1904115"(axon cytoplasm)|go:"GO:1904666"(regulation of ubiquitin protein ligase activity)|go:"GO:1990257"(piccolo-bassoon transport vesicle)	-	-	-	figure legend:st1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10116(rat-brain-cortex)|taxid:10116(Rattus norvegicus brain cortex)	-	2020/10/30	2020/10/30	rogid:DtE+ZXAZKdCMvUW5K+jXQ5bH07M10116	rogid:7wqEryp1iWbXnosW6KDHacbGxpc10116	rigid:3wclwrjZRvafcOruQOYnegkn54c	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q5XIE8	uniprotkb:P30427	intact:EBI-15348306|ensembl:ENSRNOP00000023037	intact:EBI-917155|uniprotkb:O08879|uniprotkb:O08880|uniprotkb:O08881	psi-mi:itm2b_rat(display_long)|uniprotkb:Itm2b(gene name)|psi-mi:Itm2b(display_short)|uniprotkb:Immature BRI2(gene name synonym)|uniprotkb:Transmembrane protein BRI(gene name synonym)	psi-mi:plec_rat(display_long)|uniprotkb:Plec(gene name)|psi-mi:Plec(display_short)|uniprotkb:Plec1(gene name synonym)|uniprotkb:Plectin-1(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Martins et al. (2018)	imex:IM-28469|pubmed:29476059	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26439741|imex:IM-28469-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSRNOG00000016271(gene)|ensembl:ENSRNOT00000023037(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001540"(amyloid-beta binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0010008"(endosome membrane)|go:"GO:0030660"(Golgi-associated vesicle membrane)|go:"GO:0031301"(integral component of organelle membrane)|go:"GO:0042985"(negative regulation of amyloid precursor protein biosynthetic process)|interpro:IPR007084(BRICHOS)|interpro:IPR040145|mint:Q5XIE8|refseq:NP_001006964.1|rgd:620727	interpro:IPR001452(Src homology-3)|interpro:IPR043197|mint:P30427|rgd:621649|interpro:IPR001589(Actinin-type, actin-binding, conserved site)|interpro:IPR001715(Calponin-like actin-binding)|interpro:IPR001101(Plectin repeat)|interpro:IPR005326(Plectin/S10, N-terminal)|interpro:IPR018159|interpro:IPR030269|interpro:IPR036388|interpro:IPR035915|interpro:IPR036872|interpro:IPR041573|interpro:IPR041615|go:"GO:0000902"(cell morphogenesis)|go:"GO:0002162"(dystroglycan binding)|go:"GO:0002522"(leukocyte migration involved in immune response)|go:"GO:0003334"(keratinocyte development)|go:"GO:0003779"(actin binding)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005200"(structural constituent of cytoskeleton)|go:"GO:0005737"(cytoplasm)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005903"(brush border)|go:"GO:0005925"(focal adhesion)|go:"GO:0006469"(negative regulation of protein kinase activity)|go:"GO:0007005"(mitochondrion organization)|go:"GO:0007519"(skeletal muscle tissue development)|go:"GO:0007565"(female pregnancy)|go:"GO:0007584"(response to nutrient)|go:"GO:0008092"(cytoskeletal protein binding)|go:"GO:0008307"(structural constituent of muscle)|go:"GO:0009925"(basal plasma membrane)|go:"GO:0010467"(gene expression)|go:"GO:0010761"(fibroblast migration)|go:"GO:0010818"(T cell chemotaxis)|go:"GO:0014866"(skeletal myofibril assembly)|go:"GO:0016020"(membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0016528"(sarcoplasm)|go:"GO:0019226"(transmission of nerve impulse)|go:"GO:0022011"(myelination in peripheral nervous system)|go:"GO:0030018"(Z disc)|go:"GO:0030036"(actin cytoskeleton organization)|go:"GO:0030056"(hemidesmosome)|go:"GO:0030424"(axon)|go:"GO:0030425"(dendrite)|go:"GO:0030506"(ankyrin binding)|go:"GO:0030855"(epithelial cell differentiation)|go:"GO:0031532"(actin cytoskeleton reorganization)|go:"GO:0031581"(hemidesmosome assembly)|go:"GO:0031668"(cellular response to extracellular stimulus)|go:"GO:0032094"(response to food)|go:"GO:0032287"(peripheral nervous system myelin maintenance)|go:"GO:0034613"(cellular protein localization)|go:"GO:0035264"(multicellular organism growth)|go:"GO:0042060"(wound healing)|go:"GO:0042383"(sarcolemma)|go:"GO:0043034"(costamere)|go:"GO:0043209"(myelin sheath)|go:"GO:0043292"(contractile fiber)|go:"GO:0043588"(skin development)|go:"GO:0043621"(protein self-association)|go:"GO:0043933"(protein-containing complex organization)|go:"GO:0045104"(intermediate filament cytoskeleton organization)|go:"GO:0045109"(intermediate filament organization)|go:"GO:0045214"(sarcomere organization)|go:"GO:0047485"(protein N-terminus binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0048741"(skeletal muscle fiber development)|go:"GO:0048870"(cell motility)|go:"GO:0051015"(actin filament binding)|go:"GO:0055013"(cardiac muscle cell development)|go:"GO:0061436"(establishment of skin barrier)|go:"GO:0070584"(mitochondrion morphogenesis)|go:"GO:0071498"(cellular response to fluid shear stress)|go:"GO:0071944"(cell periphery)|reactome:R-RNO-264870|reactome:R-RNO-446107	-	-	-	figure legend:st1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10116(rat-brain-cortex)|taxid:10116(Rattus norvegicus brain cortex)	-	2020/10/30	2020/10/30	rogid:DtE+ZXAZKdCMvUW5K+jXQ5bH07M10116	rogid:LQJzfjJNnr1XQnkT1Zv+NvCA71I10116	rigid:3wclwrjZRvafcOruQOYnegkn54c	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q5XIE8	uniprotkb:Q62718	intact:EBI-15348306|ensembl:ENSRNOP00000023037	intact:EBI-26437602	psi-mi:itm2b_rat(display_long)|uniprotkb:Itm2b(gene name)|psi-mi:Itm2b(display_short)|uniprotkb:Immature BRI2(gene name synonym)|uniprotkb:Transmembrane protein BRI(gene name synonym)	psi-mi:ntri_rat(display_long)|uniprotkb:Ntm(gene name)|psi-mi:Ntm(display_short)|uniprotkb:Hnt(gene name synonym)|uniprotkb:Nt(gene name synonym)|uniprotkb:GP65(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Martins et al. (2018)	imex:IM-28469|pubmed:29476059	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26439741|imex:IM-28469-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSRNOG00000016271(gene)|ensembl:ENSRNOT00000023037(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001540"(amyloid-beta binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0010008"(endosome membrane)|go:"GO:0030660"(Golgi-associated vesicle membrane)|go:"GO:0031301"(integral component of organelle membrane)|go:"GO:0042985"(negative regulation of amyloid precursor protein biosynthetic process)|interpro:IPR007084(BRICHOS)|interpro:IPR040145|mint:Q5XIE8|refseq:NP_001006964.1|rgd:620727	go:"GO:0005615"(extracellular space)|go:"GO:0005886"(plasma membrane)|go:"GO:0007155"(cell adhesion)|go:"GO:0009986"(cell surface)|go:"GO:0010977"(negative regulation of neuron projection development)|go:"GO:0021549"(cerebellum development)|go:"GO:0030424"(axon)|go:"GO:0031225"(anchored component of membrane)|go:"GO:0032355"(response to estradiol)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0060076"(excitatory synapse)|reactome:R-RNO-163125|mint:Q62718|refseq:NP_059050.1|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR036179|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR013098(Immunoglobulin I-set)|interpro:IPR003599(Immunoglobulin subtype)|interpro:IPR003598(Immunoglobulin subtype 2)|rgd:620958	-	-	-	figure legend:st1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10116(rat-brain-cortex)|taxid:10116(Rattus norvegicus brain cortex)	-	2020/10/30	2020/10/30	rogid:DtE+ZXAZKdCMvUW5K+jXQ5bH07M10116	rogid:i+PdnqMrxo1FUwJEdO4+27h8qMI10116	rigid:3wclwrjZRvafcOruQOYnegkn54c	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q5XIE8	uniprotkb:P12839	intact:EBI-15348306|ensembl:ENSRNOP00000023037	intact:EBI-26373136|uniprotkb:Q63370	psi-mi:itm2b_rat(display_long)|uniprotkb:Itm2b(gene name)|psi-mi:Itm2b(display_short)|uniprotkb:Immature BRI2(gene name synonym)|uniprotkb:Transmembrane protein BRI(gene name synonym)	psi-mi:nfm_rat(display_long)|uniprotkb:160 kDa neurofilament protein(gene name synonym)|uniprotkb:Neurofilament 3(gene name synonym)|uniprotkb:Neurofilament triplet M protein(gene name synonym)|uniprotkb:Nefm(gene name)|psi-mi:Nefm(display_short)|uniprotkb:Nef3(gene name synonym)|uniprotkb:Nfm(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Martins et al. (2018)	imex:IM-28469|pubmed:29476059	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26439741|imex:IM-28469-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSRNOG00000016271(gene)|ensembl:ENSRNOT00000023037(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001540"(amyloid-beta binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0010008"(endosome membrane)|go:"GO:0030660"(Golgi-associated vesicle membrane)|go:"GO:0031301"(integral component of organelle membrane)|go:"GO:0042985"(negative regulation of amyloid precursor protein biosynthetic process)|interpro:IPR007084(BRICHOS)|interpro:IPR040145|mint:Q5XIE8|refseq:NP_001006964.1|rgd:620727	go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005882"(intermediate filament)|go:"GO:0005883"(neurofilament)|go:"GO:0008088"(axo-dendritic transport)|go:"GO:0014069"(postsynaptic density)|go:"GO:0015643"(toxic substance binding)|go:"GO:0021510"(spinal cord development)|go:"GO:0021766"(hippocampus development)|go:"GO:0021987"(cerebral cortex development)|go:"GO:0030424"(axon)|go:"GO:0031133"(regulation of axon diameter)|go:"GO:0031594"(neuromuscular junction)|go:"GO:0033693"(neurofilament bundle assembly)|go:"GO:0034599"(cellular response to oxidative stress)|go:"GO:0043005"(neuron projection)|go:"GO:0043204"(perikaryon)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045104"(intermediate filament cytoskeleton organization)|go:"GO:0045105"(intermediate filament polymerization or depolymerization)|go:"GO:0045110"(intermediate filament bundle assembly)|go:"GO:0060052"(neurofilament cytoskeleton organization)|go:"GO:0071392"(cellular response to estradiol stimulus)|go:"GO:0097418"(neurofibrillary tangle)|go:"GO:0099160"(postsynaptic intermediate filament cytoskeleton)|go:"GO:0099182"(presynaptic intermediate filament cytoskeleton)|go:"GO:1903937"(response to acrylamide)|interpro:IPR002957(Keratin, type I)|interpro:IPR006821(Intermediate filament, DNA-binding region)|interpro:IPR018039|interpro:IPR027697|interpro:IPR039008|go:"GO:0031103"(axon regeneration)|dip:DIP-208N|rgd:3160|mint:P12839|refseq:NP_058725.1	-	-	-	figure legend:st1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10116(rat-brain-cortex)|taxid:10116(Rattus norvegicus brain cortex)	-	2020/10/30	2020/10/30	rogid:DtE+ZXAZKdCMvUW5K+jXQ5bH07M10116	rogid:WTqdAIK26RRBJSPTeEifkRwfgXM10116	rigid:3wclwrjZRvafcOruQOYnegkn54c	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q5XIE8	uniprotkb:Q5RJQ4	intact:EBI-15348306|ensembl:ENSRNOP00000023037	intact:EBI-2696664|ensembl:ENSRNOP00000059450	psi-mi:itm2b_rat(display_long)|uniprotkb:Itm2b(gene name)|psi-mi:Itm2b(display_short)|uniprotkb:Immature BRI2(gene name synonym)|uniprotkb:Transmembrane protein BRI(gene name synonym)	psi-mi:sir2_rat(display_long)|uniprotkb:Sirt2(gene name)|psi-mi:Sirt2(display_short)|uniprotkb:Sir2l2(gene name synonym)|uniprotkb:SIR2-like protein 2(gene name synonym)|uniprotkb:Regulatory protein SIR2 homolog 2(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Martins et al. (2018)	imex:IM-28469|pubmed:29476059	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26439741|imex:IM-28469-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSRNOG00000016271(gene)|ensembl:ENSRNOT00000023037(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001540"(amyloid-beta binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0010008"(endosome membrane)|go:"GO:0030660"(Golgi-associated vesicle membrane)|go:"GO:0031301"(integral component of organelle membrane)|go:"GO:0042985"(negative regulation of amyloid precursor protein biosynthetic process)|interpro:IPR007084(BRICHOS)|interpro:IPR040145|mint:Q5XIE8|refseq:NP_001006964.1|rgd:620727	rgd:621481|refseq:NP_001008369.1|ensembl:ENSRNOG00000020102(gene)|ensembl:ENSRNOT00000064153(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000792"(heterochromatin)|go:"GO:0003682"(chromatin binding)|go:"GO:0003950"(NAD+ ADP-ribosyltransferase activity)|go:"GO:0004407"(histone deacetylase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005694"(chromosome)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005813"(centrosome)|go:"GO:0005814"(centriole)|go:"GO:0005819"(spindle)|go:"GO:0005829"(cytosol)|go:"GO:0005874"(microtubule)|go:"GO:0005886"(plasma membrane)|go:"GO:0006471"(protein ADP-ribosylation)|go:"GO:0006476"(protein deacetylation)|go:"GO:0006914"(autophagy)|go:"GO:0007417"(central nervous system development)|go:"GO:0008270"(zinc ion binding)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0010507"(negative regulation of autophagy)|go:"GO:0010801"(negative regulation of peptidyl-threonine phosphorylation)|go:"GO:0014065"(phosphatidylinositol 3-kinase signaling)|go:"GO:0016575"(histone deacetylation)|go:"GO:0017136"(NAD-dependent histone deacetylase activity)|go:"GO:0022011"(myelination in peripheral nervous system)|go:"GO:0030426"(growth cone)|go:"GO:0030496"(midbody)|go:"GO:0031641"(regulation of myelination)|go:"GO:0032436"(positive regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0033010"(paranodal junction)|go:"GO:0033270"(paranode region of axon)|go:"GO:0033558"(protein deacetylase activity)|go:"GO:0034599"(cellular response to oxidative stress)|go:"GO:0034979"(NAD-dependent protein deacetylase activity)|go:"GO:0034983"(peptidyl-lysine deacetylation)|go:"GO:0035035"(histone acetyltransferase binding)|go:"GO:0035729"(cellular response to hepatocyte growth factor stimulus)|go:"GO:0035748"(myelin sheath abaxonal region)|go:"GO:0042177"(negative regulation of protein catabolic process)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0042903"(tubulin deacetylase activity)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043130"(ubiquitin binding)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0043204"(perikaryon)|go:"GO:0043209"(myelin sheath)|go:"GO:0043219"(lateral loop)|go:"GO:0043220"(Schmidt-Lanterman incisure)|go:"GO:0043388"(positive regulation of DNA binding)|go:"GO:0043491"(protein kinase B signaling)|go:"GO:0044224"(juxtaparanode region of axon)|go:"GO:0044242"(cellular lipid catabolic process)|go:"GO:0045598"(regulation of fat cell differentiation)|go:"GO:0045599"(negative regulation of fat cell differentiation)|go:"GO:0045836"(positive regulation of meiotic nuclear division)|go:"GO:0045843"(negative regulation of striated muscle tissue development)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046970"("NAD-dependent histone deacetylase activity (H4-K16 specific)")|go:"GO:0048012"(hepatocyte growth factor receptor signaling pathway)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0048487"(beta-tubulin binding)|go:"GO:0048715"(negative regulation of oligodendrocyte differentiation)|go:"GO:0051301"(cell division)|go:"GO:0051321"(meiotic cell cycle)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0051781"(positive regulation of cell division)|go:"GO:0051987"(positive regulation of attachment of spindle microtubules to kinetochore)|go:"GO:0061428"(negative regulation of transcription from RNA polymerase II promoter in response to hypoxia)|go:"GO:0061433"(cellular response to caloric restriction)|go:"GO:0070403"(NAD+ binding)|go:"GO:0070446"(negative regulation of oligodendrocyte progenitor proliferation)|go:"GO:0070932"(histone H3 deacetylation)|go:"GO:0070933"(histone H4 deacetylation)|go:"GO:0071219"(cellular response to molecule of bacterial origin)|go:"GO:0071456"(cellular response to hypoxia)|go:"GO:0071872"(cellular response to epinephrine stimulus)|go:"GO:0072686"(mitotic spindle)|go:"GO:0072687"(meiotic spindle)|go:"GO:0090042"(tubulin deacetylation)|go:"GO:0097386"(glial cell projection)|go:"GO:0097456"(terminal loop)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099149"(regulation of postsynaptic neurotransmitter receptor internalization)|go:"GO:1900119"(positive regulation of execution phase of apoptosis)|go:"GO:1900195"(positive regulation of oocyte maturation)|go:"GO:1900226"(negative regulation of NLRP3 inflammasome complex assembly)|go:"GO:1900425"(negative regulation of defense response to bacterium)|go:"GO:2000378"(negative regulation of reactive oxygen species metabolic process)|go:"GO:2000777"(positive regulation of proteasomal ubiquitin-dependent protein catabolic process involved in cellular response to hypoxia)|interpro:IPR003000(NAD-dependent histone deacetylase, silent information regulator Sir2)|interpro:IPR017328(NAD-dependent deacetylase sirtuin-2, eukaryota)|interpro:IPR026590|interpro:IPR026591|interpro:IPR029035|mint:Q5RJQ4|reactome:R-RNO-2995383	-	-	-	figure legend:st1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10116(rat-brain-cortex)|taxid:10116(Rattus norvegicus brain cortex)	-	2020/10/30	2020/10/30	rogid:DtE+ZXAZKdCMvUW5K+jXQ5bH07M10116	rogid:yxpJ/hJp1J7pE2ctnECN4j+HkoA10116	rigid:3wclwrjZRvafcOruQOYnegkn54c	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q5XIE8	uniprotkb:Q62812	intact:EBI-15348306|ensembl:ENSRNOP00000023037	intact:EBI-5747325	psi-mi:itm2b_rat(display_long)|uniprotkb:Itm2b(gene name)|psi-mi:Itm2b(display_short)|uniprotkb:Immature BRI2(gene name synonym)|uniprotkb:Transmembrane protein BRI(gene name synonym)	psi-mi:myh9_rat(display_long)|uniprotkb:Myh9(gene name)|psi-mi:Myh9(display_short)|uniprotkb:Cellular myosin heavy chain, type A(gene name synonym)|uniprotkb:Myosin heavy chain 9(gene name synonym)|uniprotkb:Myosin heavy chain, non-muscle IIa(gene name synonym)|uniprotkb:Non-muscle myosin heavy chain A(gene name synonym)|uniprotkb:Non-muscle myosin heavy chain IIa(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Martins et al. (2018)	imex:IM-28469|pubmed:29476059	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26439741|imex:IM-28469-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSRNOG00000016271(gene)|ensembl:ENSRNOT00000023037(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001540"(amyloid-beta binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0010008"(endosome membrane)|go:"GO:0030660"(Golgi-associated vesicle membrane)|go:"GO:0031301"(integral component of organelle membrane)|go:"GO:0042985"(negative regulation of amyloid precursor protein biosynthetic process)|interpro:IPR007084(BRICHOS)|interpro:IPR040145|mint:Q5XIE8|refseq:NP_001006964.1|rgd:620727	rgd:3140|interpro:IPR000048(IQ calmodulin-binding region)|interpro:IPR001609(Myosin head, motor region)|interpro:IPR004009(Myosin, N-terminal, SH3-like)|interpro:IPR002928(Myosin tail)|interpro:IPR008989(Myosin S1 fragment, N-terminal)|interpro:IPR036961|mint:Q62812|interpro:IPR027417|go:"GO:0000146"(microfilament motor activity)|go:"GO:0000212"(meiotic spindle organization)|go:"GO:0000904"(cell morphogenesis involved in differentiation)|go:"GO:0001525"(angiogenesis)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0001725"(stress fiber)|go:"GO:0001726"(ruffle)|go:"GO:0001768"(establishment of T cell polarity)|go:"GO:0001772"(immunological synapse)|go:"GO:0001778"(plasma membrane repair)|go:"GO:0001931"(uropod)|go:"GO:0001965"(G-protein alpha-subunit binding)|go:"GO:0003779"(actin binding)|go:"GO:0005178"(integrin binding)|go:"GO:0005391"("P-type sodium:potassium-exchanging transporter activity")|go:"GO:0005516"(calmodulin binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005819"(spindle)|go:"GO:0005826"(actomyosin contractile ring)|go:"GO:0005829"(cytosol)|go:"GO:0005884"(actin filament)|go:"GO:0005886"(plasma membrane)|go:"GO:0005903"(brush border)|go:"GO:0005912"(adherens junction)|go:"GO:0005938"(cell cortex)|go:"GO:0006509"(membrane protein ectodomain proteolysis)|go:"GO:0006911"(phagocytosis, engulfment)|go:"GO:0007155"(cell adhesion)|go:"GO:0007520"(myoblast fusion)|go:"GO:0008360"(regulation of cell shape)|go:"GO:0009898"(cytoplasmic side of plasma membrane)|go:"GO:0015031"(protein transport)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0016328"(lateral plasma membrane)|go:"GO:0016459"(myosin complex)|go:"GO:0016460"(myosin II complex)|go:"GO:0016887"(ATP hydrolysis activity)|go:"GO:0019901"(protein kinase binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030027"(lamellipodium)|go:"GO:0030048"(actin filament-based movement)|go:"GO:0030220"(platelet formation)|go:"GO:0030224"(monocyte differentiation)|go:"GO:0030863"(cortical cytoskeleton)|go:"GO:0031032"(actomyosin structure organization)|go:"GO:0031252"(cell leading edge)|go:"GO:0031532"(actin cytoskeleton reorganization)|go:"GO:0031594"(neuromuscular junction)|go:"GO:0031762"(follicle-stimulating hormone receptor binding)|go:"GO:0032154"(cleavage furrow)|go:"GO:0032418"(lysosome localization)|go:"GO:0032506"(cytokinetic process)|go:"GO:0032796"(uropod organization)|go:"GO:0032962"(positive regulation of inositol trisphosphate biosynthetic process)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035774"(positive regulation of insulin secretion involved in cellular response to glucose stimulus)|go:"GO:0036120"(cellular response to platelet-derived growth factor stimulus)|go:"GO:0042641"(actomyosin)|go:"GO:0042699"(follicle-stimulating hormone signaling pathway)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043495"(protein-membrane adaptor activity)|go:"GO:0043531"(ADP binding)|go:"GO:0043534"(blood vessel endothelial cell migration)|go:"GO:0045055"(regulated exocytosis)|go:"GO:0045745"(positive regulation of G protein-coupled receptor signaling pathway)|go:"GO:0045807"(positive regulation of endocytosis)|go:"GO:0050766"(positive regulation of phagocytosis)|go:"GO:0051015"(actin filament binding)|go:"GO:0051017"(actin filament bundle assembly)|go:"GO:0051295"(establishment of meiotic spindle localization)|go:"GO:0051482"(positive regulation of cytosolic calcium ion concentration involved in phospholipase C-activating G protein-coupled signaling pathway)|go:"GO:0051894"(positive regulation of focal adhesion assembly)|go:"GO:0060471"(cortical granule exocytosis)|go:"GO:0060473"(cortical granule)|go:"GO:0070374"(positive regulation of ERK1 and ERK2 cascade)|go:"GO:0070650"(actin filament bundle distribution)|go:"GO:0071260"(cellular response to mechanical stimulus)|go:"GO:0097110"(scaffold protein binding)|go:"GO:0097513"(myosin II filament)|go:"GO:0098609"(cell-cell adhesion)|go:"GO:1903919"(negative regulation of actin filament severing)|go:"GO:1903923"(positive regulation of protein processing in phagocytic vesicle)|go:"GO:1904753"(negative regulation of vascular associated smooth muscle cell migration)|go:"GO:1905684"(regulation of plasma membrane repair)|reactome:R-RNO-2029482|reactome:R-RNO-5627123	-	-	-	figure legend:st1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10116(rat-brain-cortex)|taxid:10116(Rattus norvegicus brain cortex)	-	2020/10/30	2020/10/30	rogid:DtE+ZXAZKdCMvUW5K+jXQ5bH07M10116	rogid:6JXGCXNFsQdsUBb5t+ubhweRA8Y10116	rigid:3wclwrjZRvafcOruQOYnegkn54c	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q5XIE8	uniprotkb:Q9JLT0	intact:EBI-15348306|ensembl:ENSRNOP00000023037	intact:EBI-26373055	psi-mi:itm2b_rat(display_long)|uniprotkb:Itm2b(gene name)|psi-mi:Itm2b(display_short)|uniprotkb:Immature BRI2(gene name synonym)|uniprotkb:Transmembrane protein BRI(gene name synonym)	psi-mi:myh10_rat(display_long)|uniprotkb:Cellular myosin heavy chain, type B(gene name synonym)|uniprotkb:Myosin heavy chain 10(gene name synonym)|uniprotkb:Myosin heavy chain, non-muscle IIb(gene name synonym)|uniprotkb:Non-muscle myosin heavy chain B(gene name synonym)|uniprotkb:Non-muscle myosin heavy chain IIb(gene name synonym)|uniprotkb:Myh10(gene name)|psi-mi:Myh10(display_short)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Martins et al. (2018)	imex:IM-28469|pubmed:29476059	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26439741|imex:IM-28469-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSRNOG00000016271(gene)|ensembl:ENSRNOT00000023037(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001540"(amyloid-beta binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0010008"(endosome membrane)|go:"GO:0030660"(Golgi-associated vesicle membrane)|go:"GO:0031301"(integral component of organelle membrane)|go:"GO:0042985"(negative regulation of amyloid precursor protein biosynthetic process)|interpro:IPR007084(BRICHOS)|interpro:IPR040145|mint:Q5XIE8|refseq:NP_001006964.1|rgd:620727	go:"GO:0007097"(nuclear migration)|go:"GO:0007155"(cell adhesion)|go:"GO:0007409"(axonogenesis)|go:"GO:0007411"(axon guidance)|go:"GO:0007420"(brain development)|go:"GO:0007507"(heart development)|go:"GO:0007512"(adult heart development)|go:"GO:0008283"(cell population proliferation)|go:"GO:0008360"(regulation of cell shape)|go:"GO:0009898"(cytoplasmic side of plasma membrane)|go:"GO:0016459"(myosin complex)|go:"GO:0016460"(myosin II complex)|go:"GO:0021592"(fourth ventricle development)|go:"GO:0021670"(lateral ventricle development)|go:"GO:0021678"(third ventricle development)|go:"GO:0021680"(cerebellar Purkinje cell layer development)|go:"GO:0006930"(substrate-dependent cell migration, cell extension)|go:"GO:0030036"(actin cytoskeleton organization)|go:"GO:0030048"(actin filament-based movement)|go:"GO:0030239"(myofibril assembly)|go:"GO:0030424"(axon)|go:"GO:0030426"(growth cone)|go:"GO:0030496"(midbody)|go:"GO:0031032"(actomyosin structure organization)|go:"GO:0031175"(neuron projection development)|go:"GO:0031594"(neuromuscular junction)|go:"GO:0032154"(cleavage furrow)|go:"GO:0035613"(RNA stem-loop binding)|go:"GO:0035904"(aorta development)|go:"GO:0042641"(actomyosin)|go:"GO:0042802"(identical protein binding)|go:"GO:0043005"(neuron projection)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043197"(dendritic spine)|go:"GO:0043531"(ADP binding)|go:"GO:0048027"(mRNA 5'-UTR binding)|go:"GO:0050714"(positive regulation of protein secretion)|go:"GO:0050885"(neuromuscular process controlling balance)|go:"GO:0051015"(actin filament binding)|go:"GO:0051017"(actin filament bundle assembly)|go:"GO:0055003"(cardiac myofibril assembly)|go:"GO:0055015"(ventricular cardiac muscle cell development)|go:"GO:0060041"(retina development in camera-type eye)|go:"GO:0060976"(coronary vasculature development)|go:"GO:0030027"(lamellipodium)|go:"GO:0070650"(actin filament bundle distribution)|go:"GO:0097513"(myosin II filament)|go:"GO:0098871"(postsynaptic actin cytoskeleton)|go:"GO:0098974"(postsynaptic actin cytoskeleton organization)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:1905274"(regulation of modification of postsynaptic actin cytoskeleton)|reactome:R-RNO-5627123|go:"GO:0000146"(microfilament motor activity)|go:"GO:0000281"(mitotic cytokinesis)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0001725"(stress fiber)|go:"GO:0001764"(neuron migration)|go:"GO:0001778"(plasma membrane repair)|go:"GO:0003279"(cardiac septum development)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005819"(spindle)|go:"GO:0005829"(cytosol)|go:"GO:0005844"(polysome)|go:"GO:0005903"(brush border)|go:"GO:0005938"(cell cortex)|go:"GO:0006887"(exocytosis)|rgd:71000|mint:Q9JLT0|interpro:IPR000048(IQ calmodulin-binding region)|interpro:IPR036961|interpro:IPR001609(Myosin head, motor region)|interpro:IPR004009(Myosin, N-terminal, SH3-like)|interpro:IPR008989(Myosin S1 fragment, N-terminal)|interpro:IPR002928(Myosin tail)|interpro:IPR027417|refseq:NP_113708.1	-	-	-	figure legend:st1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10116(rat-brain-cortex)|taxid:10116(Rattus norvegicus brain cortex)	-	2020/10/30	2020/10/30	rogid:DtE+ZXAZKdCMvUW5K+jXQ5bH07M10116	rogid:A2Z4b2T6i49aTpwnqohYbOIrw7M10116	rigid:3wclwrjZRvafcOruQOYnegkn54c	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q5XIE8	uniprotkb:P13832	intact:EBI-15348306|ensembl:ENSRNOP00000023037	intact:EBI-21297735|ensembl:ENSRNOP00000021048	psi-mi:itm2b_rat(display_long)|uniprotkb:Itm2b(gene name)|psi-mi:Itm2b(display_short)|uniprotkb:Immature BRI2(gene name synonym)|uniprotkb:Transmembrane protein BRI(gene name synonym)	psi-mi:mrlca_rat(display_long)|uniprotkb:Rlc-a(gene name)|psi-mi:Rlc-a(display_short)|uniprotkb:Myosin regulatory light chain 2-A, smooth muscle isoform(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Martins et al. (2018)	imex:IM-28469|pubmed:29476059	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26439741|imex:IM-28469-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSRNOG00000016271(gene)|ensembl:ENSRNOT00000023037(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001540"(amyloid-beta binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0010008"(endosome membrane)|go:"GO:0030660"(Golgi-associated vesicle membrane)|go:"GO:0031301"(integral component of organelle membrane)|go:"GO:0042985"(negative regulation of amyloid precursor protein biosynthetic process)|interpro:IPR007084(BRICHOS)|interpro:IPR040145|mint:Q5XIE8|refseq:NP_001006964.1|rgd:620727	ensembl:ENSRNOG00000015278(gene)|ensembl:ENSRNOT00000021048(transcript)|go:"GO:0001725"(stress fiber)|go:"GO:0005509"(calcium ion binding)|go:"GO:0008360"(regulation of cell shape)|go:"GO:0016460"(myosin II complex)|go:"GO:0030018"(Z disc)|go:"GO:0035254"(glutamate receptor binding)|go:"GO:0072659"(protein localization to plasma membrane)|interpro:IPR002048(Calcium-binding EF-hand)|interpro:IPR011992(EF-Hand type)|interpro:IPR018247|mint:P13832|reactome:R-RNO-3928664|reactome:R-RNO-445355|refseq:NP_001128489.1|refseq:XP_006245730.1	-	-	-	figure legend:st1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10116(rat-brain-cortex)|taxid:10116(Rattus norvegicus brain cortex)	-	2020/10/30	2020/10/30	rogid:DtE+ZXAZKdCMvUW5K+jXQ5bH07M10116	rogid:4E6Q/Ilwmfu3aaQ8ArPbEd6jCYs10116	rigid:3wclwrjZRvafcOruQOYnegkn54c	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q5XIE8	uniprotkb:Q63345	intact:EBI-15348306|ensembl:ENSRNOP00000023037	intact:EBI-26437576	psi-mi:itm2b_rat(display_long)|uniprotkb:Itm2b(gene name)|psi-mi:Itm2b(display_short)|uniprotkb:Immature BRI2(gene name synonym)|uniprotkb:Transmembrane protein BRI(gene name synonym)	psi-mi:mog_rat(display_long)|uniprotkb:Mog(gene name)|psi-mi:Mog(display_short)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Martins et al. (2018)	imex:IM-28469|pubmed:29476059	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26439741|imex:IM-28469-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSRNOG00000016271(gene)|ensembl:ENSRNOT00000023037(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001540"(amyloid-beta binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0010008"(endosome membrane)|go:"GO:0030660"(Golgi-associated vesicle membrane)|go:"GO:0031301"(integral component of organelle membrane)|go:"GO:0042985"(negative regulation of amyloid precursor protein biosynthetic process)|interpro:IPR007084(BRICHOS)|interpro:IPR040145|mint:Q5XIE8|refseq:NP_001006964.1|rgd:620727	go:"GO:0001817"(regulation of cytokine production)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0007155"(cell adhesion)|go:"GO:0007568"(aging)|go:"GO:0009897"(external side of plasma membrane)|go:"GO:0009986"(cell surface)|go:"GO:0016021"(integral component of membrane)|go:"GO:0033993"(response to lipid)|go:"GO:0043209"(myelin sheath)|go:"GO:0045121"(membrane raft)|go:"GO:0050852"(T cell receptor signaling pathway)|go:"GO:0051593"(response to folic acid)|rcsb pdb:1PKO|rcsb pdb:1PKQ|rcsb pdb:3CSP|mint:Q63345|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR036179|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR003599(Immunoglobulin subtype)|interpro:IPR013106(Immunoglobulin V-set)|interpro:IPR016663(Myelin-oligodendrocyte glycoprotein)|rgd:3102	-	-	-	figure legend:st1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10116(rat-brain-cortex)|taxid:10116(Rattus norvegicus brain cortex)	-	2020/10/30	2020/10/30	rogid:DtE+ZXAZKdCMvUW5K+jXQ5bH07M10116	rogid:Xwqfja7qnPwG/22GvWV7ODGhbGU10116	rigid:3wclwrjZRvafcOruQOYnegkn54c	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q5XIE8	uniprotkb:P07722	intact:EBI-15348306|ensembl:ENSRNOP00000023037	intact:EBI-26373743|ensembl:ENSRNOP00000028544|uniprotkb:P02685|uniprotkb:P07723	psi-mi:itm2b_rat(display_long)|uniprotkb:Itm2b(gene name)|psi-mi:Itm2b(display_short)|uniprotkb:Immature BRI2(gene name synonym)|uniprotkb:Transmembrane protein BRI(gene name synonym)	psi-mi:mag_rat(display_long)|uniprotkb:1B236(gene name synonym)|uniprotkb:Brain neuron cytoplasmic protein 3(gene name synonym)|uniprotkb:Sialic acid-binding Ig-like lectin 4a(gene name synonym)|uniprotkb:Mag(gene name)|psi-mi:Mag(display_short)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Martins et al. (2018)	imex:IM-28469|pubmed:29476059	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26439741|imex:IM-28469-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSRNOG00000016271(gene)|ensembl:ENSRNOT00000023037(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001540"(amyloid-beta binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0010008"(endosome membrane)|go:"GO:0030660"(Golgi-associated vesicle membrane)|go:"GO:0031301"(integral component of organelle membrane)|go:"GO:0042985"(negative regulation of amyloid precursor protein biosynthetic process)|interpro:IPR007084(BRICHOS)|interpro:IPR040145|mint:Q5XIE8|refseq:NP_001006964.1|rgd:620727	interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR036179|mint:P07722|reactome:R-RNO-193634|reactome:R-RNO-210991|ensembl:ENSRNOG00000021023(gene)|ensembl:ENSRNOT00000028544(transcript)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0007155"(cell adhesion)|go:"GO:0007399"(nervous system development)|go:"GO:0010977"(negative regulation of neuron projection development)|go:"GO:0019226"(transmission of nerve impulse)|go:"GO:0019901"(protein kinase binding)|go:"GO:0022010"(central nervous system myelination)|go:"GO:0030246"(carbohydrate binding)|go:"GO:0030517"(negative regulation of axon extension)|go:"GO:0031103"(axon regeneration)|go:"GO:0031643"(positive regulation of myelination)|go:"GO:0033691"(sialic acid binding)|go:"GO:0035749"(myelin sheath adaxonal region)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043209"(myelin sheath)|go:"GO:0043218"(compact myelin)|go:"GO:0043220"(Schmidt-Lanterman incisure)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0045121"(membrane raft)|go:"GO:0045665"(negative regulation of neuron differentiation)|go:"GO:0048711"(positive regulation of astrocyte differentiation)|go:"GO:0071260"(cellular response to mechanical stimulus)|go:"GO:0097453"(mesaxon)|go:"GO:0098742"(cell-cell adhesion via plasma-membrane adhesion molecules)|go:"GO:1905576"(ganglioside GT1b binding)|interpro:IPR003598(Immunoglobulin subtype 2)|interpro:IPR003599(Immunoglobulin subtype)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR013162(CD80-like, immunoglobulin C2-set)|go:"GO:0033270"(paranode region of axon)|rgd:3035|refseq:NP_058886.1|refseq:XP_006228886.1|refseq:XP_008757360.1|refseq:XP_017444540.1|refseq:XP_017444541.1|refseq:XP_017444542.1	-	-	-	figure legend:st1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10116(rat-brain-cortex)|taxid:10116(Rattus norvegicus brain cortex)	-	2020/10/30	2020/10/30	rogid:DtE+ZXAZKdCMvUW5K+jXQ5bH07M10116	rogid:WjoXy9hFKXqk5kuzguBEIx7yGIc10116	rigid:3wclwrjZRvafcOruQOYnegkn54c	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q5XIE8	uniprotkb:P60203	intact:EBI-15348306|ensembl:ENSRNOP00000023037	intact:EBI-8848294|uniprotkb:P04400|uniprotkb:P06905|uniprotkb:Q561K5|ensembl:ENSRNOP00000003283	psi-mi:itm2b_rat(display_long)|uniprotkb:Itm2b(gene name)|psi-mi:Itm2b(display_short)|uniprotkb:Immature BRI2(gene name synonym)|uniprotkb:Transmembrane protein BRI(gene name synonym)	psi-mi:mypr_rat(display_long)|uniprotkb:Plp1(gene name)|psi-mi:Plp1(display_short)|uniprotkb:Plp(gene name synonym)|uniprotkb:Lipophilin(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Martins et al. (2018)	imex:IM-28469|pubmed:29476059	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26439741|imex:IM-28469-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSRNOG00000016271(gene)|ensembl:ENSRNOT00000023037(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001540"(amyloid-beta binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0010008"(endosome membrane)|go:"GO:0030660"(Golgi-associated vesicle membrane)|go:"GO:0031301"(integral component of organelle membrane)|go:"GO:0042985"(negative regulation of amyloid precursor protein biosynthetic process)|interpro:IPR007084(BRICHOS)|interpro:IPR040145|mint:Q5XIE8|refseq:NP_001006964.1|rgd:620727	refseq:XP_017457402.1|refseq:NP_112252.1|rgd:3354|ensembl:ENSRNOG00000002419(gene)|ensembl:ENSRNOT00000003283(transcript)|go:"GO:0005886"(plasma membrane)|go:"GO:0006954"(inflammatory response)|go:"GO:0008366"(axon ensheathment)|go:"GO:0010001"(glial cell differentiation)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0014002"(astrocyte development)|go:"GO:0019911"(structural constituent of myelin sheath)|go:"GO:0022010"(central nervous system myelination)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0031175"(neuron projection development)|go:"GO:0034683"(integrin alphav-beta3 complex)|go:"GO:0042552"(myelination)|go:"GO:0042759"(long-chain fatty acid biosynthetic process)|go:"GO:0043209"(myelin sheath)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0061564"(axon development)|go:"GO:0098990"(AMPA selective glutamate receptor signaling pathway)|go:"GO:1904427"(positive regulation of calcium ion transmembrane transport)|interpro:IPR001614(Myelin proteolipid protein PLP)|interpro:IPR018237|mint:P60203	-	-	-	figure legend:st1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10116(rat-brain-cortex)|taxid:10116(Rattus norvegicus brain cortex)	-	2020/10/30	2020/10/30	rogid:DtE+ZXAZKdCMvUW5K+jXQ5bH07M10116	rogid:b7pt7FJVt10Iu1tTMeiVYEu5r/k10116	rigid:3wclwrjZRvafcOruQOYnegkn54c	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q5XIE8	uniprotkb:D3ZHV2	intact:EBI-15348306|ensembl:ENSRNOP00000023037	intact:EBI-26437518	psi-mi:itm2b_rat(display_long)|uniprotkb:Itm2b(gene name)|psi-mi:Itm2b(display_short)|uniprotkb:Immature BRI2(gene name synonym)|uniprotkb:Transmembrane protein BRI(gene name synonym)	psi-mi:macf1_rat(display_long)|uniprotkb:Macf1(gene name)|psi-mi:Macf1(display_short)|uniprotkb:Acf7(gene name synonym)|uniprotkb:Aclp7(gene name synonym)|uniprotkb:Macf(gene name synonym)|uniprotkb:Actin cross-linking family 7(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Martins et al. (2018)	imex:IM-28469|pubmed:29476059	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26439741|imex:IM-28469-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSRNOG00000016271(gene)|ensembl:ENSRNOT00000023037(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001540"(amyloid-beta binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0010008"(endosome membrane)|go:"GO:0030660"(Golgi-associated vesicle membrane)|go:"GO:0031301"(integral component of organelle membrane)|go:"GO:0042985"(negative regulation of amyloid precursor protein biosynthetic process)|interpro:IPR007084(BRICHOS)|interpro:IPR040145|mint:Q5XIE8|refseq:NP_001006964.1|rgd:620727	go:"GO:0150011"(regulation of neuron projection arborization)|go:"GO:0001707"(mesoderm formation)|go:"GO:0003779"(actin binding)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005874"(microtubule)|go:"GO:0005886"(plasma membrane)|go:"GO:0006620"(posttranslational protein targeting to endoplasmic reticulum membrane)|go:"GO:0007163"(establishment or maintenance of cell polarity)|go:"GO:0008017"(microtubule binding)|go:"GO:0010632"(regulation of epithelial cell migration)|go:"GO:0014069"(postsynaptic density)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0016020"(membrane)|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0030177"(positive regulation of Wnt signaling pathway)|go:"GO:0030334"(regulation of cell migration)|go:"GO:0032587"(ruffle membrane)|go:"GO:0032886"(regulation of microtubule-based process)|go:"GO:0042060"(wound healing)|go:"GO:0043001"(Golgi to plasma membrane protein transport)|go:"GO:0045104"(intermediate filament cytoskeleton organization)|go:"GO:0045773"(positive regulation of axon extension)|go:"GO:0051011"(microtubule minus-end binding)|go:"GO:0051015"(actin filament binding)|go:"GO:0051893"(regulation of focal adhesion assembly)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|mint:D3ZHV2|refseq:XP_017448990.1|interpro:IPR001589(Actinin-type, actin-binding, conserved site)|interpro:IPR001715(Calponin-like actin-binding)|interpro:IPR036872|interpro:IPR041615|interpro:IPR041573|interpro:IPR011992(EF-Hand type)|interpro:IPR018247|interpro:IPR002048(Calcium-binding EF-hand)|interpro:IPR003108(Growth-arrest-specific protein 2)|interpro:IPR036534|interpro:IPR043197|interpro:IPR001452(Src homology-3)|interpro:IPR018159|interpro:IPR002017(Spectrin repeat)|rgd:1306057	-	-	-	figure legend:st1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10116(rat-brain-cortex)|taxid:10116(Rattus norvegicus brain cortex)	-	2020/10/30	2020/10/30	rogid:DtE+ZXAZKdCMvUW5K+jXQ5bH07M10116	rogid:z44YaT5kXMwxgUqKagQIR8nZzug10116	rigid:3wclwrjZRvafcOruQOYnegkn54c	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q5XIE8	uniprotkb:D4A7N1	intact:EBI-15348306|ensembl:ENSRNOP00000023037	intact:EBI-26437502|ensembl:ENSRNOP00000073575	psi-mi:itm2b_rat(display_long)|uniprotkb:Itm2b(gene name)|psi-mi:Itm2b(display_short)|uniprotkb:Immature BRI2(gene name synonym)|uniprotkb:Transmembrane protein BRI(gene name synonym)	psi-mi:mic25_rat(display_long)|uniprotkb:Chchd6(gene name)|psi-mi:Chchd6(display_short)|uniprotkb:Mic25(gene name synonym)|uniprotkb:Coiled-coil-helix-coiled-coil-helix domain-containing protein 6(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Martins et al. (2018)	imex:IM-28469|pubmed:29476059	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26439741|imex:IM-28469-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSRNOG00000016271(gene)|ensembl:ENSRNOT00000023037(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001540"(amyloid-beta binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0010008"(endosome membrane)|go:"GO:0030660"(Golgi-associated vesicle membrane)|go:"GO:0031301"(integral component of organelle membrane)|go:"GO:0042985"(negative regulation of amyloid precursor protein biosynthetic process)|interpro:IPR007084(BRICHOS)|interpro:IPR040145|mint:Q5XIE8|refseq:NP_001006964.1|rgd:620727	ensembl:ENSRNOG00000060248(gene)|ensembl:ENSRNOT00000088753(transcript)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005829"(cytosol)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0042407"(cristae formation)|go:"GO:0061617"(MICOS complex)|interpro:IPR042860|mint:D4A7N1|refseq:NP_001100078.1|rgd:1304561	-	-	-	figure legend:st1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10116(rat-brain-cortex)|taxid:10116(Rattus norvegicus brain cortex)	-	2020/10/30	2020/10/30	rogid:DtE+ZXAZKdCMvUW5K+jXQ5bH07M10116	rogid:jjViah3UrbBOjNpCuJ9AICI4vmE10116	rigid:3wclwrjZRvafcOruQOYnegkn54c	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q5XIE8	uniprotkb:Q62813	intact:EBI-15348306|ensembl:ENSRNOP00000023037	intact:EBI-26437483|uniprotkb:Q6VUH9	psi-mi:itm2b_rat(display_long)|uniprotkb:Itm2b(gene name)|psi-mi:Itm2b(display_short)|uniprotkb:Immature BRI2(gene name synonym)|uniprotkb:Transmembrane protein BRI(gene name synonym)	psi-mi:lsamp_rat(display_long)|uniprotkb:Lsamp(gene name)|psi-mi:Lsamp(display_short)|uniprotkb:Lamp(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Martins et al. (2018)	imex:IM-28469|pubmed:29476059	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26439741|imex:IM-28469-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSRNOG00000016271(gene)|ensembl:ENSRNOT00000023037(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001540"(amyloid-beta binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0010008"(endosome membrane)|go:"GO:0030660"(Golgi-associated vesicle membrane)|go:"GO:0031301"(integral component of organelle membrane)|go:"GO:0042985"(negative regulation of amyloid precursor protein biosynthetic process)|interpro:IPR007084(BRICHOS)|interpro:IPR040145|mint:Q5XIE8|refseq:NP_001006964.1|rgd:620727	go:"GO:0005886"(plasma membrane)|go:"GO:0007155"(cell adhesion)|go:"GO:0031225"(anchored component of membrane)|go:"GO:0035641"(locomotory exploration behavior)|reactome:R-RNO-163125|mint:Q62813|refseq:NP_058938.1|refseq:XP_006248401.1|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR036179|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR013098(Immunoglobulin I-set)|interpro:IPR003599(Immunoglobulin subtype)|interpro:IPR003598(Immunoglobulin subtype 2)|rgd:71102	-	-	-	figure legend:st1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10116(rat-brain-cortex)|taxid:10116(Rattus norvegicus brain cortex)	-	2020/10/30	2020/10/30	rogid:DtE+ZXAZKdCMvUW5K+jXQ5bH07M10116	rogid:6BAFouzZzIUyYWrT4mMyKtsOojY10116	rigid:3wclwrjZRvafcOruQOYnegkn54c	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q5XIE8	uniprotkb:P56536	intact:EBI-15348306|ensembl:ENSRNOP00000023037	intact:EBI-994504	psi-mi:itm2b_rat(display_long)|uniprotkb:Itm2b(gene name)|psi-mi:Itm2b(display_short)|uniprotkb:Immature BRI2(gene name synonym)|uniprotkb:Transmembrane protein BRI(gene name synonym)	psi-mi:kif5c_rat(display_long)|uniprotkb:Kinesin heavy chain neuron-specific 2(gene name synonym)|uniprotkb:Kif5c(gene name)|psi-mi:Kif5c(display_short)|uniprotkb:Nkhc2(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Martins et al. (2018)	imex:IM-28469|pubmed:29476059	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26439741|imex:IM-28469-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSRNOG00000016271(gene)|ensembl:ENSRNOT00000023037(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001540"(amyloid-beta binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0010008"(endosome membrane)|go:"GO:0030660"(Golgi-associated vesicle membrane)|go:"GO:0031301"(integral component of organelle membrane)|go:"GO:0042985"(negative regulation of amyloid precursor protein biosynthetic process)|interpro:IPR007084(BRICHOS)|interpro:IPR040145|mint:Q5XIE8|refseq:NP_001006964.1|rgd:620727	go:"GO:0003777"(microtubule motor activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005871"(kinesin complex)|go:"GO:0005874"(microtubule)|go:"GO:0007018"(microtubule-based movement)|go:"GO:0007411"(axon guidance)|go:"GO:0008017"(microtubule binding)|go:"GO:0008045"(motor neuron axon guidance)|go:"GO:0008574"(plus-end-directed microtubule motor activity)|go:"GO:0030425"(dendrite)|go:"GO:0030705"(cytoskeleton-dependent intracellular transport)|go:"GO:0032839"(dendrite cytoplasm)|go:"GO:0034190"(apolipoprotein receptor binding)|go:"GO:0035253"(ciliary rootlet)|go:"GO:0043005"(neuron projection)|go:"GO:0043025"(neuronal cell body)|go:"GO:0044295"(axonal growth cone)|go:"GO:0046034"(ATP metabolic process)|go:"GO:0048489"(synaptic vesicle transport)|go:"GO:0051028"(mRNA transport)|go:"GO:0098963"(dendritic transport of messenger ribonucleoprotein complex)|go:"GO:0098964"(anterograde dendritic transport of messenger ribonucleoprotein complex)|go:"GO:0098971"(anterograde dendritic transport of neurotransmitter receptor complex)|go:"GO:0099641"(anterograde axonal protein transport)|go:"GO:0150034"(distal axon)|go:"GO:1904115"(axon cytoplasm)|rcsb pdb:2KIN|rcsb pdb:3KIN|rgd:1308539|interpro:IPR019821|interpro:IPR001752(Kinesin, motor region)|interpro:IPR027417|mint:P56536|interpro:IPR036961	-	-	-	figure legend:st1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10116(rat-brain-cortex)|taxid:10116(Rattus norvegicus brain cortex)	-	2020/10/30	2020/10/30	rogid:DtE+ZXAZKdCMvUW5K+jXQ5bH07M10116	rogid:XicHwXiTTxlnHBH1NkJ0SCgSGzY10116	rigid:3wclwrjZRvafcOruQOYnegkn54c	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q5XIE8	uniprotkb:Q9ESM2	intact:EBI-15348306|ensembl:ENSRNOP00000023037	intact:EBI-26437461	psi-mi:itm2b_rat(display_long)|uniprotkb:Itm2b(gene name)|psi-mi:Itm2b(display_short)|uniprotkb:Immature BRI2(gene name synonym)|uniprotkb:Transmembrane protein BRI(gene name synonym)	psi-mi:hpln2_rat(display_long)|uniprotkb:Hapln2(gene name)|psi-mi:Hapln2(display_short)|uniprotkb:Bral1(gene name synonym)|uniprotkb:Brain link protein 1(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Martins et al. (2018)	imex:IM-28469|pubmed:29476059	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26439741|imex:IM-28469-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSRNOG00000016271(gene)|ensembl:ENSRNOT00000023037(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001540"(amyloid-beta binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0010008"(endosome membrane)|go:"GO:0030660"(Golgi-associated vesicle membrane)|go:"GO:0031301"(integral component of organelle membrane)|go:"GO:0042985"(negative regulation of amyloid precursor protein biosynthetic process)|interpro:IPR007084(BRICHOS)|interpro:IPR040145|mint:Q5XIE8|refseq:NP_001006964.1|rgd:620727	go:"GO:0001501"(skeletal system development)|go:"GO:0005540"(hyaluronic acid binding)|go:"GO:0005576"(extracellular region)|go:"GO:0007155"(cell adhesion)|go:"GO:0007417"(central nervous system development)|go:"GO:0008065"(establishment of blood-nerve barrier)|go:"GO:0031012"(extracellular matrix)|go:"GO:0085029"(extracellular matrix assembly)|mint:Q9ESM2|refseq:NP_071621.1|interpro:IPR016186(C-type lectin-like)|interpro:IPR016187(C-type lectin fold)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR036179|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR003599(Immunoglobulin subtype)|interpro:IPR003598(Immunoglobulin subtype 2)|interpro:IPR013106(Immunoglobulin V-set)|interpro:IPR000538(Link)|rgd:621854	-	-	-	figure legend:st1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10116(rat-brain-cortex)|taxid:10116(Rattus norvegicus brain cortex)	-	2020/10/30	2020/10/30	rogid:DtE+ZXAZKdCMvUW5K+jXQ5bH07M10116	rogid:297Sn7Zp2xwT0u36s49tA1bzdUs10116	rigid:3wclwrjZRvafcOruQOYnegkn54c	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q5XIE8	uniprotkb:P02262	intact:EBI-15348306|ensembl:ENSRNOP00000023037	intact:EBI-5747219	psi-mi:itm2b_rat(display_long)|uniprotkb:Itm2b(gene name)|psi-mi:Itm2b(display_short)|uniprotkb:Immature BRI2(gene name synonym)|uniprotkb:Transmembrane protein BRI(gene name synonym)	psi-mi:h2a1_rat(display_long)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Martins et al. (2018)	imex:IM-28469|pubmed:29476059	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26439741|imex:IM-28469-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSRNOG00000016271(gene)|ensembl:ENSRNOT00000023037(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001540"(amyloid-beta binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0010008"(endosome membrane)|go:"GO:0030660"(Golgi-associated vesicle membrane)|go:"GO:0031301"(integral component of organelle membrane)|go:"GO:0042985"(negative regulation of amyloid precursor protein biosynthetic process)|interpro:IPR007084(BRICHOS)|interpro:IPR040145|mint:Q5XIE8|refseq:NP_001006964.1|rgd:620727	interpro:IPR009072(Histone-fold)|interpro:IPR007125(Histone core)|interpro:IPR002119(Histone H2A)|mint:P02262|interpro:IPR032454|interpro:IPR032458|go:"GO:0000786"(nucleosome)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0006342"|go:"GO:0046982"(protein heterodimerization activity)	-	-	-	figure legend:st1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10116(rat-brain-cortex)|taxid:10116(Rattus norvegicus brain cortex)	-	2020/10/30	2020/10/30	rogid:DtE+ZXAZKdCMvUW5K+jXQ5bH07M10116	rogid:yNvHACh66Sn9zW5OVCHxC5BdNKA10116	rigid:3wclwrjZRvafcOruQOYnegkn54c	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q5XIE8	uniprotkb:Q794E4	intact:EBI-15348306|ensembl:ENSRNOP00000023037	intact:EBI-919306|ensembl:ENSRNOP00000019529|ensembl:ENSRNOP00000068652|ensembl:ENSRNOP00000069655	psi-mi:itm2b_rat(display_long)|uniprotkb:Itm2b(gene name)|psi-mi:Itm2b(display_short)|uniprotkb:Immature BRI2(gene name synonym)|uniprotkb:Transmembrane protein BRI(gene name synonym)	psi-mi:hnrpf_rat(display_long)|uniprotkb:Hnrnpf(gene name)|psi-mi:Hnrnpf(display_short)|uniprotkb:Hnrpf(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Martins et al. (2018)	imex:IM-28469|pubmed:29476059	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26439741|imex:IM-28469-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSRNOG00000016271(gene)|ensembl:ENSRNOT00000023037(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001540"(amyloid-beta binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0010008"(endosome membrane)|go:"GO:0030660"(Golgi-associated vesicle membrane)|go:"GO:0031301"(integral component of organelle membrane)|go:"GO:0042985"(negative regulation of amyloid precursor protein biosynthetic process)|interpro:IPR007084(BRICHOS)|interpro:IPR040145|mint:Q5XIE8|refseq:NP_001006964.1|rgd:620727	rgd:620366|refseq:NP_001032362.1|refseq:NP_001032363.1|refseq:NP_001032364.1|refseq:NP_071792.1|refseq:XP_008761484.1|refseq:XP_017448358.1|refseq:XP_017448359.1|refseq:XP_017448360.1|refseq:XP_017448361.1|refseq:XP_017448362.1|refseq:XP_017448363.1|refseq:XP_017448364.1|ensembl:ENSRNOG00000014562(gene)|ensembl:ENSRNOT00000019529(transcript)|ensembl:ENSRNOT00000083843(transcript)|ensembl:ENSRNOT00000091765(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0003727"(single-stranded RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006397"(mRNA processing)|go:"GO:0008380"(RNA splicing)|go:"GO:0017025"(TBP-class protein binding)|go:"GO:0043484"(regulation of RNA splicing)|go:"GO:0071013"(catalytic step 2 spliceosome)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR012996(Zinc finger, CHHC-type)|interpro:IPR035979|mint:Q794E4|reactome:R-RNO-6803529|reactome:R-RNO-72163	-	-	-	figure legend:st1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10116(rat-brain-cortex)|taxid:10116(Rattus norvegicus brain cortex)	-	2020/10/30	2020/10/30	rogid:DtE+ZXAZKdCMvUW5K+jXQ5bH07M10116	rogid:Ntkz1kjm7RteL6dBzMmC0sipvCk10116	rigid:3wclwrjZRvafcOruQOYnegkn54c	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q5XIE8	uniprotkb:Q9JJ54	intact:EBI-15348306|ensembl:ENSRNOP00000023037	intact:EBI-2696704|uniprotkb:Q9JJ51|uniprotkb:Q9JJ52|uniprotkb:Q9JJ53|ensembl:ENSRNOP00000046491|uniprotkb:G3V9G2|uniprotkb:P17132	psi-mi:itm2b_rat(display_long)|uniprotkb:Itm2b(gene name)|psi-mi:Itm2b(display_short)|uniprotkb:Immature BRI2(gene name synonym)|uniprotkb:Transmembrane protein BRI(gene name synonym)	psi-mi:hnrpd_rat(display_long)|uniprotkb:Hnrnpd(gene name)|psi-mi:Hnrnpd(display_short)|uniprotkb:Auf1(gene name synonym)|uniprotkb:Hnrpd(gene name synonym)|uniprotkb:AU-rich element RNA-binding protein 1(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Martins et al. (2018)	imex:IM-28469|pubmed:29476059	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26439741|imex:IM-28469-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSRNOG00000016271(gene)|ensembl:ENSRNOT00000023037(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001540"(amyloid-beta binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0010008"(endosome membrane)|go:"GO:0030660"(Golgi-associated vesicle membrane)|go:"GO:0031301"(integral component of organelle membrane)|go:"GO:0042985"(negative regulation of amyloid precursor protein biosynthetic process)|interpro:IPR007084(BRICHOS)|interpro:IPR040145|mint:Q5XIE8|refseq:NP_001006964.1|rgd:620727	rgd:620365|refseq:NP_001076008.1|refseq:NP_001076009.1|refseq:NP_001076010.1|refseq:NP_077380.2|ensembl:ENSRNOG00000002292(gene)|ensembl:ENSRNOT00000047840(transcript)|go:"GO:0001889"(liver development)|go:"GO:0003680"(minor groove of adenine-thymine-rich DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006913"(nucleocytoplasmic transport)|go:"GO:0007420"(brain development)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0000291"(nuclear-transcribed mRNA catabolic process, exonucleolytic)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0021549"(cerebellum development)|go:"GO:0032204"(regulation of telomere maintenance)|go:"GO:0032355"(response to estradiol)|go:"GO:0035925"(mRNA 3'-UTR AU-rich region binding)|go:"GO:0042162"(telomeric DNA binding)|go:"GO:0042752"(regulation of circadian rhythm)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0043488"(regulation of mRNA stability)|go:"GO:0045202"(synapse)|go:"GO:0045727"(positive regulation of translation)|go:"GO:0048255"(mRNA stabilization)|go:"GO:0051592"(response to calcium ion)|go:"GO:0051602"(response to electrical stimulus)|go:"GO:0061158"(3'-UTR-mediated mRNA destabilization)|go:"GO:0071230"(cellular response to amino acid stimulus)|go:"GO:0071392"(cellular response to estradiol stimulus)|go:"GO:0071732"(cellular response to nitric oxide)|go:"GO:0097167"(circadian regulation of translation)|go:"GO:1901355"(response to rapamycin)|go:"GO:1904355"(positive regulation of telomere capping)|go:"GO:1904383"(response to sodium phosphate)|go:"GO:1904586"(cellular response to putrescine)|go:"GO:1905663"(positive regulation of telomerase RNA reverse transcriptase activity)|go:"GO:1990828"(hepatocyte dedifferentiation)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR012956(CBF, N-terminal)|interpro:IPR035979|mint:Q9JJ54|reactome:R-RNO-450408|reactome:R-RNO-72163	-	-	-	figure legend:st1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10116(rat-brain-cortex)|taxid:10116(Rattus norvegicus brain cortex)	-	2020/10/30	2020/10/30	rogid:DtE+ZXAZKdCMvUW5K+jXQ5bH07M10116	rogid:fV91RKUcQMG97Am2q0D9jmps1Uw10116	rigid:3wclwrjZRvafcOruQOYnegkn54c	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q5XIE8	uniprotkb:Q6URK4	intact:EBI-15348306|ensembl:ENSRNOP00000023037	intact:EBI-2696754|uniprotkb:Q6URK3|ensembl:ENSRNOP00000069876	psi-mi:itm2b_rat(display_long)|uniprotkb:Itm2b(gene name)|psi-mi:Itm2b(display_short)|uniprotkb:Immature BRI2(gene name synonym)|uniprotkb:Transmembrane protein BRI(gene name synonym)	psi-mi:roa3_rat(display_long)|uniprotkb:Hnrnpa3(gene name)|psi-mi:Hnrnpa3(display_short)|uniprotkb:Hnrpa3(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Martins et al. (2018)	imex:IM-28469|pubmed:29476059	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26439741|imex:IM-28469-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSRNOG00000016271(gene)|ensembl:ENSRNOT00000023037(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001540"(amyloid-beta binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0010008"(endosome membrane)|go:"GO:0030660"(Golgi-associated vesicle membrane)|go:"GO:0031301"(integral component of organelle membrane)|go:"GO:0042985"(negative regulation of amyloid precursor protein biosynthetic process)|interpro:IPR007084(BRICHOS)|interpro:IPR040145|mint:Q5XIE8|refseq:NP_001006964.1|rgd:620727	rgd:727807|refseq:NP_001104764.1|refseq:NP_001104765.1|refseq:NP_937765.1|refseq:XP_008760133.1|refseq:XP_008760134.1|ensembl:ENSRNOG00000052968(gene)|ensembl:ENSRNOT00000078872(transcript)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006397"(mRNA processing)|go:"GO:0008380"(RNA splicing)|go:"GO:0014069"(postsynaptic density)|go:"GO:0035770"(ribonucleoprotein granule)|go:"GO:0043005"(neuron projection)|go:"GO:0051028"(mRNA transport)|go:"GO:0051033"(RNA transmembrane transporter activity)|go:"GO:0071013"(catalytic step 2 spliceosome)|go:"GO:1990124"(messenger ribonucleoprotein complex)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR034513|interpro:IPR034516|interpro:IPR035979|mint:Q6URK4|reactome:R-RNO-72163	-	-	-	figure legend:st1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10116(rat-brain-cortex)|taxid:10116(Rattus norvegicus brain cortex)	-	2020/10/30	2020/10/30	rogid:DtE+ZXAZKdCMvUW5K+jXQ5bH07M10116	rogid:KcZjXvHON9QZSqHWi4nWSDz/HtE10116	rigid:3wclwrjZRvafcOruQOYnegkn54c	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q5XIE8	uniprotkb:Q68FP1	intact:EBI-15348306|ensembl:ENSRNOP00000023037	intact:EBI-6096401|ensembl:ENSRNOP00000025857	psi-mi:itm2b_rat(display_long)|uniprotkb:Itm2b(gene name)|psi-mi:Itm2b(display_short)|uniprotkb:Immature BRI2(gene name synonym)|uniprotkb:Transmembrane protein BRI(gene name synonym)	psi-mi:gels_rat(display_long)|uniprotkb:Gsn(gene name)|psi-mi:Gsn(display_short)|uniprotkb:Actin-depolymerizing factor(gene name synonym)|uniprotkb:Brevin(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Martins et al. (2018)	imex:IM-28469|pubmed:29476059	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26439741|imex:IM-28469-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSRNOG00000016271(gene)|ensembl:ENSRNOT00000023037(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001540"(amyloid-beta binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0010008"(endosome membrane)|go:"GO:0030660"(Golgi-associated vesicle membrane)|go:"GO:0031301"(integral component of organelle membrane)|go:"GO:0042985"(negative regulation of amyloid precursor protein biosynthetic process)|interpro:IPR007084(BRICHOS)|interpro:IPR040145|mint:Q5XIE8|refseq:NP_001006964.1|rgd:620727	rgd:1303089|refseq:NP_001004080.1|refseq:XP_006234102.1|ensembl:ENSRNOG00000018991(gene)|ensembl:ENSRNOT00000025857(transcript)|go:"GO:0001726"(ruffle)|go:"GO:0002102"(podosome)|go:"GO:0003779"(actin binding)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005546"(phosphatidylinositol-4,5-bisphosphate binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005925"(focal adhesion)|go:"GO:0006911"(phagocytosis, engulfment)|go:"GO:0006915"(apoptotic process)|go:"GO:0007417"(central nervous system development)|go:"GO:0007568"(aging)|go:"GO:0008154"(actin polymerization or depolymerization)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0014003"(oligodendrocyte development)|go:"GO:0014891"(striated muscle atrophy)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0016192"(vesicle-mediated transport)|go:"GO:0016528"(sarcoplasm)|go:"GO:0030027"(lamellipodium)|go:"GO:0030031"(cell projection assembly)|go:"GO:0030036"(actin cytoskeleton organization)|go:"GO:0030041"(actin filament polymerization)|go:"GO:0030042"(actin filament depolymerization)|go:"GO:0030155"(regulation of cell adhesion)|go:"GO:0030478"(actin cap)|go:"GO:0030864"(cortical actin cytoskeleton)|go:"GO:0031648"(protein destabilization)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035994"(response to muscle stretch)|go:"GO:0036313"(phosphatidylinositol 3-kinase catalytic subunit binding)|go:"GO:0042060"(wound healing)|go:"GO:0042246"(tissue regeneration)|go:"GO:0042989"(sequestering of actin monomers)|go:"GO:0043209"(myelin sheath)|go:"GO:0045010"(actin nucleation)|go:"GO:0045159"(myosin II binding)|go:"GO:0045335"(phagocytic vesicle)|go:"GO:0046597"(negative regulation of viral entry into host cell)|go:"GO:0048015"(phosphatidylinositol-mediated signaling)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051014"(actin filament severing)|go:"GO:0051015"(actin filament binding)|go:"GO:0051016"(barbed-end actin filament capping)|go:"GO:0051127"(positive regulation of actin nucleation)|go:"GO:0051593"(response to folic acid)|go:"GO:0051693"(actin filament capping)|go:"GO:0055119"(relaxation of cardiac muscle)|go:"GO:0060271"(cilium assembly)|go:"GO:0071276"(cellular response to cadmium ion)|go:"GO:0071346"(cellular response to interferon-gamma)|go:"GO:0071801"(regulation of podosome assembly)|go:"GO:0086003"(cardiac muscle cell contraction)|go:"GO:0090527"(actin filament reorganization)|go:"GO:0097017"(renal protein absorption)|go:"GO:0097284"(hepatocyte apoptotic process)|go:"GO:1902174"(positive regulation of keratinocyte apoptotic process)|go:"GO:1903903"(regulation of establishment of T cell polarity)|go:"GO:1903906"(regulation of plasma membrane raft polarization)|go:"GO:1903909"(regulation of receptor clustering)|go:"GO:1903923"(positive regulation of protein processing in phagocytic vesicle)|go:"GO:1990000"(amyloid fibril formation)|go:"GO:2001269"(positive regulation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway)|interpro:IPR007122(Gelsolin)|interpro:IPR007123(Gelsolin region)|interpro:IPR029006|interpro:IPR030004|mint:Q68FP1|reactome:R-RNO-264870|reactome:R-RNO-6798695|go:"GO:0045471"(response to ethanol)	-	-	-	figure legend:st1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10116(rat-brain-cortex)|taxid:10116(Rattus norvegicus brain cortex)	-	2020/10/30	2020/10/30	rogid:DtE+ZXAZKdCMvUW5K+jXQ5bH07M10116	rogid:VEJohA79kwmQ8WB+zZ5DO5Wjw1g10116	rigid:3wclwrjZRvafcOruQOYnegkn54c	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q5XIE8	uniprotkb:Q62696	intact:EBI-15348306|ensembl:ENSRNOP00000023037	intact:EBI-389325	psi-mi:itm2b_rat(display_long)|uniprotkb:Itm2b(gene name)|psi-mi:Itm2b(display_short)|uniprotkb:Immature BRI2(gene name synonym)|uniprotkb:Transmembrane protein BRI(gene name synonym)	psi-mi:dlg1_rat(display_long)|uniprotkb:Dlg1(gene name)|psi-mi:Dlg1(display_short)|uniprotkb:Synapse-associated protein 97(gene name synonym)|uniprotkb:Dlgh1(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Martins et al. (2018)	imex:IM-28469|pubmed:29476059	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26439741|imex:IM-28469-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSRNOG00000016271(gene)|ensembl:ENSRNOT00000023037(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001540"(amyloid-beta binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0010008"(endosome membrane)|go:"GO:0030660"(Golgi-associated vesicle membrane)|go:"GO:0031301"(integral component of organelle membrane)|go:"GO:0042985"(negative regulation of amyloid precursor protein biosynthetic process)|interpro:IPR007084(BRICHOS)|interpro:IPR040145|mint:Q5XIE8|refseq:NP_001006964.1|rgd:620727	rgd:2505|refseq:NP_036920.1|go:"GO:0043219"(lateral loop)|go:"GO:0043268"(positive regulation of potassium ion transport)|go:"GO:0043622"(cortical microtubule organization)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0045121"(membrane raft)|go:"GO:0045197"(establishment or maintenance of epithelial cell apical/basal polarity)|go:"GO:0045202"(synapse)|go:"GO:0045211"(postsynaptic membrane)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0048608"(reproductive structure development)|go:"GO:0048704"(embryonic skeletal system morphogenesis)|go:"GO:0048729"(tissue morphogenesis)|go:"GO:0048745"(smooth muscle tissue development)|go:"GO:0050680"(negative regulation of epithelial cell proliferation)|go:"GO:0051660"(establishment of centrosome localization)|go:"GO:0051898"(negative regulation of protein kinase B signaling)|go:"GO:0060022"(hard palate development)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0070373"(negative regulation of ERK1 and ERK2 cascade)|go:"GO:0070830"(bicellular tight junction assembly)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0097016"(L27 domain binding)|go:"GO:0097025"(MPP7-DLG1-LIN7 complex)|go:"GO:0097060"(synaptic membrane)|go:"GO:0097120"(receptor localization to synapse)|go:"GO:0098609"(cell-cell adhesion)|go:"GO:0098839"(postsynaptic density membrane)|go:"GO:0098911"(regulation of ventricular cardiac muscle cell action potential)|go:"GO:0098919"(structural constituent of postsynaptic density)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099092"(postsynaptic density, intracellular component)|go:"GO:0099645"(neurotransmitter receptor localization to postsynaptic specialization membrane)|go:"GO:1902473"(regulation of protein localization to synapse)|go:"GO:1903078"(positive regulation of protein localization to plasma membrane)|go:"GO:1903286"(regulation of potassium ion import)|go:"GO:1903753"(negative regulation of p38MAPK cascade)|go:"GO:1903760"(regulation of voltage-gated potassium channel activity involved in ventricular cardiac muscle cell action potential repolarization)|go:"GO:1903764"(regulation of potassium ion export across plasma membrane)|go:"GO:2000134"(negative regulation of G1/S transition of mitotic cell cycle)|interpro:IPR001452(Src homology-3)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR004172(L27)|interpro:IPR008144(Guanylate kinase)|interpro:IPR008145(Guanylate kinase/L-type calcium channel region)|interpro:IPR015143(L27-1)|interpro:IPR016313("Membrane-associated guanylate kinase (MAGUK) scaffold protein")|interpro:IPR019583|interpro:IPR019590|interpro:IPR020590|interpro:IPR027417|interpro:IPR036028|interpro:IPR036034|interpro:IPR036892|rcsb pdb:1RSO|rcsb pdb:1ZOK|rcsb pdb:2AWU|rcsb pdb:2AWW|rcsb pdb:2AWX|rcsb pdb:2G2L|rcsb pdb:2I0I|rcsb pdb:2I0L|rcsb pdb:3UAT|reactome:R-RNO-399719|reactome:R-RNO-438066|reactome:R-RNO-451308|reactome:R-RNO-5673001|reactome:R-RNO-8849932|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0005874"(microtubule)|go:"GO:0005886"(plasma membrane)|go:"GO:0005902"(microvillus)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005923"(bicellular tight junction)|go:"GO:0007015"(actin filament organization)|go:"GO:0007155"(cell adhesion)|go:"GO:0007268"(chemical synaptic transmission)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008104"(protein localization)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0008360"(regulation of cell shape)|go:"GO:0009898"(cytoplasmic side of plasma membrane)|go:"GO:0009925"(basal plasma membrane)|go:"GO:0014069"(postsynaptic density)|go:"GO:0015459"(potassium channel regulator activity)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0016328"(lateral plasma membrane)|go:"GO:0019894"(kinesin binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0019902"(phosphatase binding)|go:"GO:0030054"(cell junction)|go:"GO:0030165"(PDZ domain binding)|go:"GO:0030315"(T-tubule)|go:"GO:0030425"(dendrite)|go:"GO:0030432"(peristalsis)|go:"GO:0030672"(synaptic vesicle membrane)|go:"GO:0030838"(positive regulation of actin filament polymerization)|go:"GO:0030866"(cortical actin cytoskeleton organization)|go:"GO:0030953"(astral microtubule organization)|go:"GO:0031253"(cell projection membrane)|go:"GO:0031434"(mitogen-activated protein kinase kinase binding)|go:"GO:0031579"(membrane raft organization)|go:"GO:0031594"(neuromuscular junction)|go:"GO:0031641"(regulation of myelination)|go:"GO:0032147"(activation of protein kinase activity)|go:"GO:0032880"(regulation of protein localization)|go:"GO:0033268"(node of Ranvier)|go:"GO:0033270"(paranode region of axon)|go:"GO:0034629"|go:"GO:0035255"(ionotropic glutamate receptor binding)|go:"GO:0035748"(myelin sheath abaxonal region)|go:"GO:0042110"(T cell activation)|go:"GO:0042130"(negative regulation of T cell proliferation)|go:"GO:0042391"(regulation of membrane potential)|go:"GO:0042734"(presynaptic membrane)|go:"GO:0042982"(amyloid precursor protein metabolic process)|go:"GO:0043005"(neuron projection)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043113"(receptor clustering)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0001657"(ureteric bud development)|go:"GO:0001658"(branching involved in ureteric bud morphogenesis)|go:"GO:0001771"(immunological synapse formation)|go:"GO:0001772"(immunological synapse)|go:"GO:0001935"(endothelial cell proliferation)|go:"GO:0002088"(lens development in camera-type eye)|go:"GO:0005604"(basement membrane)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|mint:Q62696|dip:DIP-31527N	-	-	-	figure legend:st1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10116(rat-brain-cortex)|taxid:10116(Rattus norvegicus brain cortex)	-	2020/10/30	2020/10/30	rogid:DtE+ZXAZKdCMvUW5K+jXQ5bH07M10116	rogid:ThHAJAsBhWNjz4P6frniUm2xaJI10116	rigid:3wclwrjZRvafcOruQOYnegkn54c	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q5XIE8	uniprotkb:O08651	intact:EBI-15348306|ensembl:ENSRNOP00000023037	intact:EBI-915450|uniprotkb:Q546Q9|ensembl:ENSRNOP00000053019	psi-mi:itm2b_rat(display_long)|uniprotkb:Itm2b(gene name)|psi-mi:Itm2b(display_short)|uniprotkb:Immature BRI2(gene name synonym)|uniprotkb:Transmembrane protein BRI(gene name synonym)	psi-mi:sera_rat(display_long)|uniprotkb:Phgdh(gene name)|psi-mi:Phgdh(display_short)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Martins et al. (2018)	imex:IM-28469|pubmed:29476059	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26439741|imex:IM-28469-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSRNOG00000016271(gene)|ensembl:ENSRNOT00000023037(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001540"(amyloid-beta binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0010008"(endosome membrane)|go:"GO:0030660"(Golgi-associated vesicle membrane)|go:"GO:0031301"(integral component of organelle membrane)|go:"GO:0042985"(negative regulation of amyloid precursor protein biosynthetic process)|interpro:IPR007084(BRICHOS)|interpro:IPR040145|mint:Q5XIE8|refseq:NP_001006964.1|rgd:620727	rgd:61987|refseq:NP_113808.1|refseq:XP_006233072.1|ensembl:ENSRNOG00000019328(gene)|ensembl:ENSRNOT00000056173(transcript)|go:"GO:0004617"(phosphoglycerate dehydrogenase activity)|go:"GO:0006541"(glutamine metabolic process)|go:"GO:0006544"(glycine metabolic process)|go:"GO:0006563"(L-serine metabolic process)|go:"GO:0006564"(L-serine biosynthetic process)|go:"GO:0006566"(threonine metabolic process)|go:"GO:0009070"(serine family amino acid biosynthetic process)|go:"GO:0009448"(gamma-aminobutyric acid metabolic process)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0019530"(taurine metabolic process)|go:"GO:0021510"(spinal cord development)|go:"GO:0021782"(glial cell development)|go:"GO:0021915"(neural tube development)|go:"GO:0022008"(neurogenesis)|go:"GO:0031175"(neuron projection development)|go:"GO:0051287"(NAD binding)|go:"GO:0070314"(G1 to G0 transition)|interpro:IPR006139(D-isomer specific 2-hydroxyacid dehydrogenase, catalytic region)|interpro:IPR006140(D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding)|interpro:IPR006236(D-3-phosphoglycerate dehydrogenase)|interpro:IPR029009|interpro:IPR029752|interpro:IPR029753|interpro:IPR036291|mint:O08651|reactome:R-RNO-977347	-	-	-	figure legend:st1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10116(rat-brain-cortex)|taxid:10116(Rattus norvegicus brain cortex)	-	2020/10/30	2020/10/30	rogid:DtE+ZXAZKdCMvUW5K+jXQ5bH07M10116	rogid:HxRSndxyMrzoSms31Sg/CpNk5eU10116	rigid:3wclwrjZRvafcOruQOYnegkn54c	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q5XIE8	uniprotkb:P97846	intact:EBI-15348306|ensembl:ENSRNOP00000023037	intact:EBI-26437421|ensembl:ENSRNOP00000027505	psi-mi:itm2b_rat(display_long)|uniprotkb:Itm2b(gene name)|psi-mi:Itm2b(display_short)|uniprotkb:Immature BRI2(gene name synonym)|uniprotkb:Transmembrane protein BRI(gene name synonym)	psi-mi:cntp1_rat(display_long)|uniprotkb:Cntnap1(gene name)|psi-mi:Cntnap1(display_short)|uniprotkb:Caspr(gene name synonym)|uniprotkb:Nrxn4(gene name synonym)|uniprotkb:Neurexin IV(gene name synonym)|uniprotkb:Neurexin-4(gene name synonym)|uniprotkb:Paranodin(gene name synonym)|uniprotkb:p190(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Martins et al. (2018)	imex:IM-28469|pubmed:29476059	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26439741|imex:IM-28469-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSRNOG00000016271(gene)|ensembl:ENSRNOT00000023037(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001540"(amyloid-beta binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0010008"(endosome membrane)|go:"GO:0030660"(Golgi-associated vesicle membrane)|go:"GO:0031301"(integral component of organelle membrane)|go:"GO:0042985"(negative regulation of amyloid precursor protein biosynthetic process)|interpro:IPR007084(BRICHOS)|interpro:IPR040145|mint:Q5XIE8|refseq:NP_001006964.1|rgd:620727	ensembl:ENSRNOG00000020277(gene)|ensembl:ENSRNOT00000027505(transcript)|go:"GO:0002175"(protein localization to paranode region of axon)|go:"GO:0005918"(septate junction)|go:"GO:0007010"(cytoskeleton organization)|go:"GO:0007155"(cell adhesion)|go:"GO:0016021"(integral component of membrane)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0019227"(neuronal action potential propagation)|go:"GO:0022010"(central nervous system myelination)|go:"GO:0022011"(myelination in peripheral nervous system)|go:"GO:0030424"(axon)|go:"GO:0030913"(paranodal junction assembly)|go:"GO:0031175"(neuron projection development)|go:"GO:0033010"(paranodal junction)|go:"GO:0033270"(paranode region of axon)|go:"GO:0042552"(myelination)|go:"GO:0048787"(presynaptic active zone membrane)|go:"GO:0048812"(neuron projection morphogenesis)|go:"GO:0050884"(neuromuscular process controlling posture)|go:"GO:0050885"(neuromuscular process controlling balance)|go:"GO:0071205"(protein localization to juxtaparanode region of axon)|interpro:IPR000421(Coagulation factor 5/8 type, C-terminal)|interpro:IPR000742(EGF-like, type 3)|interpro:IPR001791(Laminin G)|interpro:IPR002181(Fibrinogen, alpha/beta/gamma chain, C-terminal globular)|interpro:IPR003585(Neurexin/syndecan/glycophorin C)|interpro:IPR008979(Galactose-binding like)|interpro:IPR013320(Concanavalin A-like lectin/glucanase, subgroup)|interpro:IPR028872|interpro:IPR036056|mint:P97846|refseq:NP_114450.1|rgd:70902	-	-	-	figure legend:st1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10116(rat-brain-cortex)|taxid:10116(Rattus norvegicus brain cortex)	-	2020/10/30	2020/10/30	rogid:DtE+ZXAZKdCMvUW5K+jXQ5bH07M10116	rogid:oJ+zmI5E4kZhbUEl3xmU8iqt8v410116	rigid:3wclwrjZRvafcOruQOYnegkn54c	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q5XIE8	uniprotkb:Q9WU82	intact:EBI-15348306|ensembl:ENSRNOP00000023037	intact:EBI-920177	psi-mi:itm2b_rat(display_long)|uniprotkb:Itm2b(gene name)|psi-mi:Itm2b(display_short)|uniprotkb:Immature BRI2(gene name synonym)|uniprotkb:Transmembrane protein BRI(gene name synonym)	psi-mi:ctnb1_rat(display_long)|uniprotkb:Ctnnb1(gene name)|psi-mi:Ctnnb1(display_short)|uniprotkb:Catnb(gene name synonym)|uniprotkb:Beta-catenin(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Martins et al. (2018)	imex:IM-28469|pubmed:29476059	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26439741|imex:IM-28469-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSRNOG00000016271(gene)|ensembl:ENSRNOT00000023037(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001540"(amyloid-beta binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0010008"(endosome membrane)|go:"GO:0030660"(Golgi-associated vesicle membrane)|go:"GO:0031301"(integral component of organelle membrane)|go:"GO:0042985"(negative regulation of amyloid precursor protein biosynthetic process)|interpro:IPR007084(BRICHOS)|interpro:IPR040145|mint:Q5XIE8|refseq:NP_001006964.1|rgd:620727	rgd:70487|refseq:NP_445809.2|refseq:XP_008764913.1|refseq:XP_017451425.1|refseq:XP_017451426.1|refseq:XP_017451428.1|refseq:XP_017451429.1|mint:Q9WU82|dip:DIP-37053N|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0000578"(embryonic axis specification)|go:"GO:0000791"(euchromatin)|go:"GO:0000904"(cell morphogenesis involved in differentiation)|go:"GO:0000922"(spindle pole)|go:"GO:0001221"(transcription coregulator binding)|go:"GO:0001501"(skeletal system development)|go:"GO:0001569"(branching involved in blood vessel morphogenesis)|go:"GO:0001570"(vasculogenesis)|go:"GO:0001658"(branching involved in ureteric bud morphogenesis)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0001702"(gastrulation with mouth forming second)|go:"GO:0001706"(endoderm formation)|go:"GO:0001708"(cell fate specification)|go:"GO:0001709"(cell fate determination)|go:"GO:0001711"(endodermal cell fate commitment)|go:"GO:0001764"(neuron migration)|go:"GO:0001822"(kidney development)|go:"GO:0001840"(neural plate development)|go:"GO:0001889"(liver development)|go:"GO:0001894"(tissue homeostasis)|go:"GO:0001944"(vasculature development)|go:"GO:0002052"(positive regulation of neuroblast proliferation)|go:"GO:0002053"(positive regulation of mesenchymal cell proliferation)|go:"GO:0002089"(lens morphogenesis in camera-type eye)|go:"GO:0003266"(regulation of secondary heart field cardioblast proliferation)|go:"GO:0003338"(metanephros morphogenesis)|go:"GO:0003340"(negative regulation of mesenchymal to epithelial transition involved in metanephros morphogenesis)|go:"GO:0003682"(chromatin binding)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005912"(adherens junction)|go:"GO:0005916"(fascia adherens)|go:"GO:0005923"(bicellular tight junction)|go:"GO:0005938"(cell cortex)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007155"(cell adhesion)|go:"GO:0007160"(cell-matrix adhesion)|go:"GO:0007268"(chemical synaptic transmission)|go:"GO:0007398"(ectoderm development)|go:"GO:0007403"(glial cell fate determination)|go:"GO:0007494"(midgut development)|go:"GO:0007507"(heart development)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008283"(cell population proliferation)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0009725"(response to hormone)|go:"GO:0009948"(anterior/posterior axis specification)|go:"GO:0009950"(dorsal/ventral axis specification)|go:"GO:0009953"(dorsal/ventral pattern formation)|go:"GO:0009954"(proximal/distal pattern formation)|go:"GO:0009987"(cellular process)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0010718"(positive regulation of epithelial to mesenchymal transition)|go:"GO:0010909"(positive regulation of heparan sulfate proteoglycan biosynthetic process)|go:"GO:0014010"(Schwann cell proliferation)|go:"GO:0014070"(response to organic cyclic compound)|go:"GO:0014704"(intercalated disc)|go:"GO:0014823"(response to activity)|go:"GO:0016020"(membrane)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016327"(apicolateral plasma membrane)|go:"GO:0016328"(lateral plasma membrane)|go:"GO:0016331"(morphogenesis of embryonic epithelium)|go:"GO:0016342"(catenin complex)|go:"GO:0016525"(negative regulation of angiogenesis)|go:"GO:0016600"(flotillin complex)|go:"GO:0016922"(nuclear receptor binding)|go:"GO:0019899"(enzyme binding)|go:"GO:0019900"(kinase binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0019903"(protein phosphatase binding)|go:"GO:0021819"(layer formation in cerebral cortex)|go:"GO:0022009"(central nervous system vasculogenesis)|go:"GO:0022405"(hair cycle process)|go:"GO:0030018"(Z disc)|go:"GO:0030027"(lamellipodium)|go:"GO:0030054"(cell junction)|go:"GO:0030097"(hemopoiesis)|go:"GO:0030154"(cell differentiation)|go:"GO:0030182"(neuron differentiation)|go:"GO:0030217"(T cell differentiation)|go:"GO:0030316"(osteoclast differentiation)|go:"GO:0030324"(lung development)|go:"GO:0030331"(estrogen receptor binding)|go:"GO:0030539"(male genitalia development)|go:"GO:0030856"(regulation of epithelial cell differentiation)|go:"GO:0030858"(positive regulation of epithelial cell differentiation)|go:"GO:0030877"(beta-catenin destruction complex)|go:"GO:0030900"(forebrain development)|go:"GO:0030901"(midbrain development)|go:"GO:0030902"(hindbrain development)|go:"GO:0030997"(regulation of centriole-centriole cohesion)|go:"GO:0031016"(pancreas development)|go:"GO:0031069"(hair follicle morphogenesis)|go:"GO:0031253"(cell projection membrane)|go:"GO:0031528"(microvillus membrane)|go:"GO:0031641"(regulation of myelination)|go:"GO:0031965"(nuclear membrane)|go:"GO:0032212"(positive regulation of telomere maintenance via telomerase)|go:"GO:0032331"(negative regulation of chondrocyte differentiation)|go:"GO:0032355"(response to estradiol)|go:"GO:0032968"(positive regulation of transcription elongation from RNA polymerase II promoter)|go:"GO:0032991"(protein-containing complex)|go:"GO:0032993"(protein-DNA complex)|go:"GO:0033077"(T cell differentiation in thymus)|go:"GO:0033234"(negative regulation of protein sumoylation)|go:"GO:0034097"(response to cytokine)|go:"GO:0034332"(adherens junction organization)|go:"GO:0034333"(adherens junction assembly)|go:"GO:0034394"(protein localization to cell surface)|go:"GO:0034613"(cellular protein localization)|go:"GO:0034750"(Scrib-APC-beta-catenin complex)|go:"GO:0035050"(embryonic heart tube development)|go:"GO:0035112"(genitalia morphogenesis)|go:"GO:0035115"(embryonic forelimb morphogenesis)|go:"GO:0035116"(embryonic hindlimb morphogenesis)|go:"GO:0035255"(ionotropic glutamate receptor binding)|go:"GO:0036023"(embryonic skeletal limb joint morphogenesis)|go:"GO:0036520"(astrocyte-dopaminergic neuron signaling)|go:"GO:0042127"(regulation of cell population proliferation)|go:"GO:0042129"(regulation of T cell proliferation)|go:"GO:0042475"(odontogenesis of dentin-containing tooth)|go:"GO:0042493"|go:"GO:0042733"(embryonic digit morphogenesis)|go:"GO:0042734"(presynaptic membrane)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0043198"(dendritic shaft)|go:"GO:0043296"(apical junction complex)|go:"GO:0043410"(positive regulation of MAPK cascade)|go:"GO:0043525"(positive regulation of neuron apoptotic process)|go:"GO:0043588"(skin development)|go:"GO:0043627"(response to estrogen)|go:"GO:0044093"(positive regulation of molecular function)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0044334"(canonical Wnt signaling pathway involved in positive regulation of epithelial to mesenchymal transition)|go:"GO:0044338"(canonical Wnt signaling pathway involved in mesenchymal stem cell differentiation)|go:"GO:0044344"(cellular response to fibroblast growth factor stimulus)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045177"(apical part of cell)|go:"GO:0045202"(synapse)|go:"GO:0045211"(postsynaptic membrane)|go:"GO:0045294"(alpha-catenin binding)|go:"GO:0045296"(cadherin binding)|go:"GO:0045445"(myoblast differentiation)|go:"GO:0045453"(bone resorption)|go:"GO:0045595"(regulation of cell differentiation)|go:"GO:0045596"(negative regulation of cell differentiation)|go:"GO:0045603"(positive regulation of endothelial cell differentiation)|go:"GO:0045667"(regulation of osteoblast differentiation)|go:"GO:0045669"(positive regulation of osteoblast differentiation)|go:"GO:0045670"(regulation of osteoclast differentiation)|go:"GO:0045671"(negative regulation of osteoclast differentiation)|go:"GO:0045743"(positive regulation of fibroblast growth factor receptor signaling pathway)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0045976"(negative regulation of mitotic cell cycle, embryonic)|go:"GO:0046332"(SMAD binding)|go:"GO:0046686"(response to cadmium ion)|go:"GO:0046849"(bone remodeling)|go:"GO:0048469"(cell maturation)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0048489"(synaptic vesicle transport)|go:"GO:0048513"(animal organ development)|go:"GO:0048538"(thymus development)|go:"GO:0048568"(embryonic organ development)|go:"GO:0048599"(oocyte development)|go:"GO:0048617"(embryonic foregut morphogenesis)|go:"GO:0048643"(positive regulation of skeletal muscle tissue development)|go:"GO:0048660"(regulation of smooth muscle cell proliferation)|go:"GO:0048715"(negative regulation of oligodendrocyte differentiation)|go:"GO:0050768"(negative regulation of neurogenesis)|go:"GO:0050808"(synapse organization)|go:"GO:0050998"(nitric-oxide synthase binding)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0051145"(smooth muscle cell differentiation)|go:"GO:0051571"(positive regulation of histone H3-K4 methylation)|go:"GO:0051884"(regulation of timing of anagen)|go:"GO:0051973"(positive regulation of telomerase activity)|go:"GO:0060066"(oviduct development)|go:"GO:0060070"(canonical Wnt signaling pathway)|go:"GO:0060173"(limb development)|go:"GO:0060439"(trachea morphogenesis)|go:"GO:0060440"(trachea formation)|go:"GO:0060441"(epithelial tube branching involved in lung morphogenesis)|go:"GO:0060479"(lung cell differentiation)|go:"GO:0060484"(lung-associated mesenchyme development)|go:"GO:0060492"(lung induction)|go:"GO:0060742"(epithelial cell differentiation involved in prostate gland development)|go:"GO:0060769"(positive regulation of epithelial cell proliferation involved in prostate gland development)|go:"GO:0060789"(hair follicle placode formation)|go:"GO:0060916"(mesenchymal cell proliferation involved in lung development)|go:"GO:0061047"(positive regulation of branching involved in lung morphogenesis)|go:"GO:0061154"(endothelial tube morphogenesis)|go:"GO:0061198"(fungiform papilla formation)|go:"GO:0061324"(canonical Wnt signaling pathway involved in positive regulation of cardiac outflow tract cell proliferation)|go:"GO:0061549"(sympathetic ganglion development)|go:"GO:0061550"(cranial ganglion development)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:0070369"(beta-catenin-TCF7L2 complex)|go:"GO:0070411"(I-SMAD binding)|go:"GO:0070602"(regulation of centromeric sister chromatid cohesion)|go:"GO:0071260"(cellular response to mechanical stimulus)|go:"GO:0071285"(cellular response to lithium ion)|go:"GO:0071363"(cellular response to growth factor stimulus)|go:"GO:0071681"(cellular response to indole-3-methanol)|go:"GO:0071944"(cell periphery)|go:"GO:0072033"(renal vesicle formation)|go:"GO:0072053"(renal inner medulla development)|go:"GO:0072054"(renal outer medulla development)|go:"GO:0072079"(nephron tubule formation)|go:"GO:0072182"(regulation of nephron tubule epithelial cell differentiation)|go:"GO:0090279"(regulation of calcium ion import)|go:"GO:0097091"(synaptic vesicle clustering)|go:"GO:0097718"(disordered domain specific binding)|go:"GO:0098609"(cell-cell adhesion)|go:"GO:0098685"(Schaffer collateral - CA1 synapse)|go:"GO:0098831"(presynaptic active zone cytoplasmic component)|go:"GO:0099092"(postsynaptic density, intracellular component)|go:"GO:0140297"(DNA-binding transcription factor binding)|go:"GO:1901215"(negative regulation of neuron death)|go:"GO:1903204"(negative regulation of oxidative stress-induced neuron death)|go:"GO:1904796"(regulation of core promoter binding)|go:"GO:1904798"(positive regulation of core promoter binding)|go:"GO:1904888"(cranial skeletal system development)|go:"GO:1904948"(midbrain dopaminergic neuron differentiation)|go:"GO:1990138"(neuron projection extension)|go:"GO:1990226"(histone methyltransferase binding)|go:"GO:1990314"(cellular response to insulin-like growth factor stimulus)|go:"GO:1990403"(embryonic brain development)|go:"GO:1990791"(dorsal root ganglion development)|go:"GO:1990907"(beta-catenin-TCF complex)|go:"GO:1990909"(Wnt signalosome)|go:"GO:2000008"(regulation of protein localization to cell surface)|go:"GO:2000017"(positive regulation of determination of dorsal identity)|go:"GO:2000179"(positive regulation of neural precursor cell proliferation)|go:"GO:2001234"(negative regulation of apoptotic signaling pathway)|interpro:IPR000225(Armadillo)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR013284(Beta-catenin)|interpro:IPR016024(Armadillo-type fold)|reactome:R-RNO-195253|reactome:R-RNO-196299|reactome:R-RNO-201681|reactome:R-RNO-201722|reactome:R-RNO-3134973|reactome:R-RNO-351906|reactome:R-RNO-3769402|reactome:R-RNO-4086398|reactome:R-RNO-418990|reactome:R-RNO-4641262|reactome:R-RNO-5218920|reactome:R-RNO-525793|reactome:R-RNO-5626467|reactome:R-RNO-8951430	-	-	-	figure legend:st1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10116(rat-brain-cortex)|taxid:10116(Rattus norvegicus brain cortex)	-	2020/10/30	2020/10/30	rogid:DtE+ZXAZKdCMvUW5K+jXQ5bH07M10116	rogid:EQ9j/nvYumuF5gT++5hCWaL8cyw10116	rigid:3wclwrjZRvafcOruQOYnegkn54c	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q5XIE8	uniprotkb:Q6KC51	intact:EBI-15348306|ensembl:ENSRNOP00000023037	intact:EBI-26437401|uniprotkb:Q6KC50	psi-mi:itm2b_rat(display_long)|uniprotkb:Itm2b(gene name)|psi-mi:Itm2b(display_short)|uniprotkb:Immature BRI2(gene name synonym)|uniprotkb:Transmembrane protein BRI(gene name synonym)	psi-mi:ablm2_rat(display_long)|uniprotkb:Ablim2(gene name)|psi-mi:Ablim2(display_short)|uniprotkb:Actin-binding LIM protein family member 2(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Martins et al. (2018)	imex:IM-28469|pubmed:29476059	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26439741|imex:IM-28469-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSRNOG00000016271(gene)|ensembl:ENSRNOT00000023037(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001540"(amyloid-beta binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0010008"(endosome membrane)|go:"GO:0030660"(Golgi-associated vesicle membrane)|go:"GO:0031301"(integral component of organelle membrane)|go:"GO:0042985"(negative regulation of amyloid precursor protein biosynthetic process)|interpro:IPR007084(BRICHOS)|interpro:IPR040145|mint:Q5XIE8|refseq:NP_001006964.1|rgd:620727	go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0030016"(myofibril)|go:"GO:0030032"(lamellipodium assembly)|go:"GO:0030036"(actin cytoskeleton organization)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|go:"GO:0051015"(actin filament binding)|mint:Q6KC51|refseq:NP_001001514.1|refseq:NP_001171166.1|interpro:IPR028450|interpro:IPR032402|interpro:IPR003128(Villin headpiece)|interpro:IPR036886|interpro:IPR001781(Zinc finger, LIM-type)|rgd:1303094	-	-	-	figure legend:st1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10116(rat-brain-cortex)|taxid:10116(Rattus norvegicus brain cortex)	-	2020/10/30	2020/10/30	rogid:DtE+ZXAZKdCMvUW5K+jXQ5bH07M10116	rogid:u7CD/CcAAKw3JVQkaKebuX8zOss10116	rigid:3wclwrjZRvafcOruQOYnegkn54c	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q5XIE8	uniprotkb:P49911	intact:EBI-15348306|ensembl:ENSRNOP00000023037	intact:EBI-1638376	psi-mi:itm2b_rat(display_long)|uniprotkb:Itm2b(gene name)|psi-mi:Itm2b(display_short)|uniprotkb:Immature BRI2(gene name synonym)|uniprotkb:Transmembrane protein BRI(gene name synonym)	psi-mi:an32a_rat(display_long)|uniprotkb:Anp32a(gene name)|psi-mi:Anp32a(display_short)|uniprotkb:Lanp(gene name synonym)|uniprotkb:Leucine-rich acidic nuclear protein(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Martins et al. (2018)	imex:IM-28469|pubmed:29476059	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26439741|imex:IM-28469-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSRNOG00000016271(gene)|ensembl:ENSRNOT00000023037(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001540"(amyloid-beta binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0010008"(endosome membrane)|go:"GO:0030660"(Golgi-associated vesicle membrane)|go:"GO:0031301"(integral component of organelle membrane)|go:"GO:0042985"(negative regulation of amyloid precursor protein biosynthetic process)|interpro:IPR007084(BRICHOS)|interpro:IPR040145|mint:Q5XIE8|refseq:NP_001006964.1|rgd:620727	mint:P49911|refseq:NP_037035.1|interpro:IPR001611(Leucine-rich repeat)|rgd:11508551|interpro:IPR032675|go:"GO:0005178"(integrin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005829"(cytosol)|go:"GO:0006913"(nucleocytoplasmic transport)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0010977"(negative regulation of neuron projection development)|go:"GO:0016363"(nuclear matrix)|go:"GO:0035067"(negative regulation of histone acetylation)|go:"GO:0042393"(histone binding)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0050839"(cell adhesion molecule binding)|reactome:R-RNO-450520	-	-	-	figure legend:st1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10116(rat-brain-cortex)|taxid:10116(Rattus norvegicus brain cortex)	-	2020/10/30	2020/10/30	rogid:DtE+ZXAZKdCMvUW5K+jXQ5bH07M10116	rogid:GifxAZWLIiSOf3Wau754tOYzrDY10116	rigid:3wclwrjZRvafcOruQOYnegkn54c	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q5XIE8	uniprotkb:P05426	intact:EBI-15348306|ensembl:ENSRNOP00000023037	intact:EBI-779677	psi-mi:itm2b_rat(display_long)|uniprotkb:Itm2b(gene name)|psi-mi:Itm2b(display_short)|uniprotkb:Immature BRI2(gene name synonym)|uniprotkb:Transmembrane protein BRI(gene name synonym)	psi-mi:rl7_rat(display_long)|uniprotkb:Rpl7(gene name)|psi-mi:Rpl7(display_short)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Martins et al. (2018)	imex:IM-28469|pubmed:29476059	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26439741|imex:IM-28469-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSRNOG00000016271(gene)|ensembl:ENSRNOT00000023037(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001540"(amyloid-beta binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0010008"(endosome membrane)|go:"GO:0030660"(Golgi-associated vesicle membrane)|go:"GO:0031301"(integral component of organelle membrane)|go:"GO:0042985"(negative regulation of amyloid precursor protein biosynthetic process)|interpro:IPR007084(BRICHOS)|interpro:IPR040145|mint:Q5XIE8|refseq:NP_001006964.1|rgd:620727	rgd:735169|interpro:IPR018038|interpro:IPR016082(Ribosomal protein L30, C-terminal)|interpro:IPR012988(Ribosomal protein L30, N-terminal)|interpro:IPR005998(Ribosomal protein L7, eukaryotic)|interpro:IPR039699|interpro:IPR035808|interpro:IPR036919|go:"GO:0000463"("maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)")|go:"GO:0003677"(DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005840"(ribosome)|go:"GO:0005844"(polysome)|go:"GO:0006364"(rRNA processing)|go:"GO:0008097"(5S rRNA binding)|go:"GO:0014069"(postsynaptic density)|go:"GO:0022625"(cytosolic large ribosomal subunit)|go:"GO:0022626"(cytosolic ribosome)|go:"GO:0031672"(A band)|go:"GO:0042273"(ribosomal large subunit biogenesis)|go:"GO:0042802"(identical protein binding)|go:"GO:0045202"(synapse)|go:"GO:0097421"(liver regeneration)|go:"GO:1990904"(ribonucleoprotein complex)|reactome:R-RNO-156827|reactome:R-RNO-1799339|reactome:R-RNO-6791226|reactome:R-RNO-72689|reactome:R-RNO-72706|reactome:R-RNO-975956|reactome:R-RNO-975957|mint:P05426	-	-	-	figure legend:st1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10116(rat-brain-cortex)|taxid:10116(Rattus norvegicus brain cortex)	-	2020/10/30	2020/10/30	rogid:DtE+ZXAZKdCMvUW5K+jXQ5bH07M10116	rogid:pIpF4885CEJGzSQVuRWK0nx1pgY10116	rigid:3wclwrjZRvafcOruQOYnegkn54c	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q5XIE8	uniprotkb:P61354	intact:EBI-15348306|ensembl:ENSRNOP00000023037	intact:EBI-352771|ensembl:ENSRNOP00000028060|uniprotkb:P08526|uniprotkb:Q5BJ97	psi-mi:itm2b_rat(display_long)|uniprotkb:Itm2b(gene name)|psi-mi:Itm2b(display_short)|uniprotkb:Immature BRI2(gene name synonym)|uniprotkb:Transmembrane protein BRI(gene name synonym)	psi-mi:rl27_rat(display_long)|uniprotkb:Rpl27(gene name)|psi-mi:Rpl27(display_short)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Martins et al. (2018)	imex:IM-28469|pubmed:29476059	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26439741|imex:IM-28469-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSRNOG00000016271(gene)|ensembl:ENSRNOT00000023037(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001540"(amyloid-beta binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0010008"(endosome membrane)|go:"GO:0030660"(Golgi-associated vesicle membrane)|go:"GO:0031301"(integral component of organelle membrane)|go:"GO:0042985"(negative regulation of amyloid precursor protein biosynthetic process)|interpro:IPR007084(BRICHOS)|interpro:IPR040145|mint:Q5XIE8|refseq:NP_001006964.1|rgd:620727	reactome:R-RNO-72706|reactome:R-RNO-975956|reactome:R-RNO-975957|reactome:R-RNO-72689|ensembl:ENSRNOG00000020674(gene)|ensembl:ENSRNOT00000028060(transcript)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005840"(ribosome)|go:"GO:0006364"(rRNA processing)|go:"GO:0006412"(translation)|go:"GO:0022625"(cytosolic large ribosomal subunit)|go:"GO:0022626"(cytosolic ribosome)|go:"GO:0098556"(cytoplasmic side of rough endoplasmic reticulum membrane)|go:"GO:1904044"(response to aldosterone)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR001141(Ribosomal protein L27e)|interpro:IPR005824(KOW)|interpro:IPR008991(Translation protein SH3-like)|interpro:IPR018262|interpro:IPR038655|interpro:IPR041991|mint:P61354|reactome:R-RNO-156827|reactome:R-RNO-1799339|reactome:R-RNO-6791226|rgd:621192|refseq:NP_071959.1	-	-	-	figure legend:st1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10116(rat-brain-cortex)|taxid:10116(Rattus norvegicus brain cortex)	-	2020/10/30	2020/10/30	rogid:DtE+ZXAZKdCMvUW5K+jXQ5bH07M10116	rogid:TLWbAcdRKUb2ijDYjSUa1sbixis10116	rigid:3wclwrjZRvafcOruQOYnegkn54c	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q5XIE8	uniprotkb:P38983	intact:EBI-15348306|ensembl:ENSRNOP00000023037	intact:EBI-917451|uniprotkb:B6ZB78|ensembl:ENSRNOP00000025224	psi-mi:itm2b_rat(display_long)|uniprotkb:Itm2b(gene name)|psi-mi:Itm2b(display_short)|uniprotkb:Immature BRI2(gene name synonym)|uniprotkb:Transmembrane protein BRI(gene name synonym)	psi-mi:rssa_rat(display_long)|uniprotkb:Laminin receptor 1(gene name synonym)|uniprotkb:37/67 kDa laminin receptor(gene name synonym)|uniprotkb:Laminin-binding protein precursor p40(gene name synonym)|uniprotkb:Rpsa(gene name)|psi-mi:Rpsa(display_short)|uniprotkb:Lamr1(gene name synonym)|uniprotkb:37 kDa laminin receptor precursor(gene name synonym)|uniprotkb:67 kDa laminin receptor(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Martins et al. (2018)	imex:IM-28469|pubmed:29476059	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26439741|imex:IM-28469-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSRNOG00000016271(gene)|ensembl:ENSRNOT00000023037(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001540"(amyloid-beta binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0010008"(endosome membrane)|go:"GO:0030660"(Golgi-associated vesicle membrane)|go:"GO:0031301"(integral component of organelle membrane)|go:"GO:0042985"(negative regulation of amyloid precursor protein biosynthetic process)|interpro:IPR007084(BRICHOS)|interpro:IPR040145|mint:Q5XIE8|refseq:NP_001006964.1|rgd:620727	rgd:71026|refseq:NP_058834.1|ensembl:ENSRNOG00000018645(gene)|ensembl:ENSRNOT00000025225(transcript)|go:"GO:0000028"(ribosomal small subunit assembly)|go:"GO:0002181"(cytoplasmic translation)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005055"(laminin receptor activity)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005604"(basement membrane)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006412"(translation)|go:"GO:0015935"(small ribosomal subunit)|go:"GO:0016020"(membrane)|go:"GO:0022626"(cytosolic ribosome)|go:"GO:0022627"(cytosolic small ribosomal subunit)|go:"GO:0030855"(epithelial cell differentiation)|go:"GO:0043022"(ribosome binding)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043236"(laminin binding)|go:"GO:0045202"(synapse)|go:"GO:0062023"(collagen-containing extracellular matrix)|go:"GO:0098609"(cell-cell adhesion)|go:"GO:0098978"(glutamatergic synapse)|interpro:IPR001865(Ribosomal protein S2)|interpro:IPR005707(Ribosomal protein S2, eukaryotic/archaeal)|interpro:IPR018130|interpro:IPR023591|interpro:IPR027498|interpro:IPR027504|interpro:IPR032281|mint:P38983|reactome:R-RNO-156827|reactome:R-RNO-1799339|reactome:R-RNO-6791226|reactome:R-RNO-72649|reactome:R-RNO-72689|reactome:R-RNO-72695|reactome:R-RNO-72702|reactome:R-RNO-72706|reactome:R-RNO-975956|reactome:R-RNO-975957	-	-	-	figure legend:st1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10116(rat-brain-cortex)|taxid:10116(Rattus norvegicus brain cortex)	-	2020/10/30	2020/10/30	rogid:DtE+ZXAZKdCMvUW5K+jXQ5bH07M10116	rogid:XVgtLKyvO/UwRSx+OqV7+lc98XI10116	rigid:3wclwrjZRvafcOruQOYnegkn54c	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q5XIE8	uniprotkb:P62703	intact:EBI-15348306|ensembl:ENSRNOP00000023037	intact:EBI-354282|uniprotkb:P12631|uniprotkb:P12750|uniprotkb:P27576|uniprotkb:Q14727|uniprotkb:P55831|ensembl:ENSRNOP00000067969	psi-mi:itm2b_rat(display_long)|uniprotkb:Itm2b(gene name)|psi-mi:Itm2b(display_short)|uniprotkb:Immature BRI2(gene name synonym)|uniprotkb:Transmembrane protein BRI(gene name synonym)	psi-mi:rs4x_rat(display_long)|uniprotkb:Rps4x(gene name)|psi-mi:Rps4x(display_short)|uniprotkb:Rps4(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Martins et al. (2018)	imex:IM-28469|pubmed:29476059	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26439741|imex:IM-28469-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSRNOG00000016271(gene)|ensembl:ENSRNOT00000023037(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001540"(amyloid-beta binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0010008"(endosome membrane)|go:"GO:0030660"(Golgi-associated vesicle membrane)|go:"GO:0031301"(integral component of organelle membrane)|go:"GO:0042985"(negative regulation of amyloid precursor protein biosynthetic process)|interpro:IPR007084(BRICHOS)|interpro:IPR040145|mint:Q5XIE8|refseq:NP_001006964.1|rgd:620727	refseq:NP_001007601.1|rgd:2324318|ensembl:ENSRNOG00000003201(gene)|go:"GO:0019843"(rRNA binding)|go:"GO:0022626"(cytosolic ribosome)|go:"GO:0022627"(cytosolic small ribosomal subunit)|go:"GO:0036464"(cytoplasmic ribonucleoprotein granule)|go:"GO:0045202"(synapse)|go:"GO:0045471"(response to ethanol)|ensembl:ENSRNOT00000076978(transcript)|go:"GO:0045727"(positive regulation of translation)|go:"GO:0003723"(RNA binding)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005840"(ribosome)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR000876(Ribosomal protein S4e)|interpro:IPR002942(RNA-binding S4)|interpro:IPR005824(KOW)|interpro:IPR013843(Ribosomal protein S4e, N-terminal)|interpro:IPR013845(Ribosomal protein S4e, central)|go:"GO:0005844"(polysome)|go:"GO:0006412"(translation)|interpro:IPR014722(Translation protein SH3-like, subgroup)|interpro:IPR018199|interpro:IPR032277|interpro:IPR036986|interpro:IPR038237|interpro:IPR041982|mint:P62703|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0015935"(small ribosomal subunit)|reactome:R-RNO-156827|reactome:R-RNO-1799339|reactome:R-RNO-6791226|reactome:R-RNO-72649|reactome:R-RNO-72689|reactome:R-RNO-72695|reactome:R-RNO-72702|reactome:R-RNO-72706|reactome:R-RNO-975956|reactome:R-RNO-975957	-	-	-	figure legend:st1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10116(rat-brain-cortex)|taxid:10116(Rattus norvegicus brain cortex)	-	2020/10/30	2020/10/30	rogid:DtE+ZXAZKdCMvUW5K+jXQ5bH07M10116	rogid:2ZuLXqBSDkK0CtN3mnIDoFAR8yI10116	rigid:3wclwrjZRvafcOruQOYnegkn54c	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q5XIE8	uniprotkb:P17074	intact:EBI-15348306|ensembl:ENSRNOP00000023037	intact:EBI-916692|ensembl:ENSRNOP00000027246	psi-mi:itm2b_rat(display_long)|uniprotkb:Itm2b(gene name)|psi-mi:Itm2b(display_short)|uniprotkb:Immature BRI2(gene name synonym)|uniprotkb:Transmembrane protein BRI(gene name synonym)	psi-mi:rs19_rat(display_long)|uniprotkb:Rps19(gene name)|psi-mi:Rps19(display_short)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Martins et al. (2018)	imex:IM-28469|pubmed:29476059	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26439741|imex:IM-28469-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSRNOG00000016271(gene)|ensembl:ENSRNOT00000023037(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001540"(amyloid-beta binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0010008"(endosome membrane)|go:"GO:0030660"(Golgi-associated vesicle membrane)|go:"GO:0031301"(integral component of organelle membrane)|go:"GO:0042985"(negative regulation of amyloid precursor protein biosynthetic process)|interpro:IPR007084(BRICHOS)|interpro:IPR040145|mint:Q5XIE8|refseq:NP_001006964.1|rgd:620727	rgd:68440|refseq:NP_001032423.1|refseq:XP_006228473.1|refseq:XP_017444775.1|refseq:XP_017444777.1|refseq:XP_017445502.1|ensembl:ENSRNOG00000037897(gene)|ensembl:ENSRNOT00000027246(transcript)|go:"GO:0000028"(ribosomal small subunit assembly)|go:"GO:0003723"(RNA binding)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005730"(nucleolus)|go:"GO:0006412"(translation)|go:"GO:0007219"(Notch signaling pathway)|go:"GO:0022627"(cytosolic small ribosomal subunit)|go:"GO:0030218"(erythrocyte differentiation)|go:"GO:0031369"(translation initiation factor binding)|go:"GO:0045202"(synapse)|interpro:IPR001266(Ribosomal protein S19e)|interpro:IPR018277|interpro:IPR036388|interpro:IPR036390|mint:P17074|reactome:R-RNO-156827|reactome:R-RNO-1799339|reactome:R-RNO-6791226|reactome:R-RNO-72649|reactome:R-RNO-72689|reactome:R-RNO-72695|reactome:R-RNO-72702|reactome:R-RNO-72706|reactome:R-RNO-975956|reactome:R-RNO-975957	-	-	-	figure legend:st1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10116(rat-brain-cortex)|taxid:10116(Rattus norvegicus brain cortex)	-	2020/10/30	2020/10/30	rogid:DtE+ZXAZKdCMvUW5K+jXQ5bH07M10116	rogid:D3A6ULv7RIjBdw3qPwrdoWZ+F4U10116	rigid:3wclwrjZRvafcOruQOYnegkn54c	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q5XIE8	uniprotkb:P62250	intact:EBI-15348306|ensembl:ENSRNOP00000023037	intact:EBI-352489|uniprotkb:P17008|ensembl:ENSRNOP00000026576	psi-mi:itm2b_rat(display_long)|uniprotkb:Itm2b(gene name)|psi-mi:Itm2b(display_short)|uniprotkb:Immature BRI2(gene name synonym)|uniprotkb:Transmembrane protein BRI(gene name synonym)	psi-mi:rs16_rat(display_long)|uniprotkb:Rps16(gene name)|psi-mi:Rps16(display_short)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Martins et al. (2018)	imex:IM-28469|pubmed:29476059	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26439741|imex:IM-28469-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSRNOG00000016271(gene)|ensembl:ENSRNOT00000023037(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001540"(amyloid-beta binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0010008"(endosome membrane)|go:"GO:0030660"(Golgi-associated vesicle membrane)|go:"GO:0031301"(integral component of organelle membrane)|go:"GO:0042985"(negative regulation of amyloid precursor protein biosynthetic process)|interpro:IPR007084(BRICHOS)|interpro:IPR040145|mint:Q5XIE8|refseq:NP_001006964.1|rgd:620727	rgd:621031|refseq:NP_001162617.1|ensembl:ENSRNOG00000019578(gene)|ensembl:ENSRNOT00000026576(transcript)|go:"GO:0000462"("maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)")|go:"GO:0003723"(RNA binding)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0006364"(rRNA processing)|go:"GO:0006412"(translation)|go:"GO:0015935"(small ribosomal subunit)|go:"GO:0022626"(cytosolic ribosome)|go:"GO:0022627"(cytosolic small ribosomal subunit)|go:"GO:0042274"(ribosomal small subunit biogenesis)|go:"GO:0097421"(liver regeneration)|go:"GO:1990830"(cellular response to leukemia inhibitory factor)|interpro:IPR000754(Ribosomal protein S9)|interpro:IPR014721(Ribosomal protein S5 domain 2-type fold)|interpro:IPR020568|interpro:IPR020574|mint:P62250|reactome:R-RNO-156827|reactome:R-RNO-1799339|reactome:R-RNO-6791226|reactome:R-RNO-72649|reactome:R-RNO-72689|reactome:R-RNO-72695|reactome:R-RNO-72702|reactome:R-RNO-72706|reactome:R-RNO-975956|reactome:R-RNO-975957	-	-	-	figure legend:st1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10116(rat-brain-cortex)|taxid:10116(Rattus norvegicus brain cortex)	-	2020/10/30	2020/10/30	rogid:DtE+ZXAZKdCMvUW5K+jXQ5bH07M10116	rogid:OrKriR6HsATLaO+drdUa2w3Gpd010116	rigid:3wclwrjZRvafcOruQOYnegkn54c	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q5XIE8	uniprotkb:P62278	intact:EBI-15348306|ensembl:ENSRNOP00000023037	intact:EBI-351861|uniprotkb:P19116|uniprotkb:Q02546|uniprotkb:Q29200|ensembl:ENSRNOP00000036690	psi-mi:itm2b_rat(display_long)|uniprotkb:Itm2b(gene name)|psi-mi:Itm2b(display_short)|uniprotkb:Immature BRI2(gene name synonym)|uniprotkb:Transmembrane protein BRI(gene name synonym)	psi-mi:rs13_rat(display_long)|uniprotkb:Rps13(gene name)|psi-mi:Rps13(display_short)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Martins et al. (2018)	imex:IM-28469|pubmed:29476059	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26439741|imex:IM-28469-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSRNOG00000016271(gene)|ensembl:ENSRNOT00000023037(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001540"(amyloid-beta binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0010008"(endosome membrane)|go:"GO:0030660"(Golgi-associated vesicle membrane)|go:"GO:0031301"(integral component of organelle membrane)|go:"GO:0042985"(negative regulation of amyloid precursor protein biosynthetic process)|interpro:IPR007084(BRICHOS)|interpro:IPR040145|mint:Q5XIE8|refseq:NP_001006964.1|rgd:620727	rgd:621027|refseq:NP_569116.1|refseq:XP_001053043.1|ensembl:ENSRNOG00000028021(gene)|ensembl:ENSRNOT00000034694(transcript)|go:"GO:0003729"(mRNA binding)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005634"(nucleus)|go:"GO:0005730"(nucleolus)|go:"GO:0006412"(translation)|go:"GO:0014069"(postsynaptic density)|go:"GO:0022626"(cytosolic ribosome)|go:"GO:0022627"(cytosolic small ribosomal subunit)|go:"GO:0033119"(negative regulation of RNA splicing)|go:"GO:0045202"(synapse)|go:"GO:0048027"(mRNA 5'-UTR binding)|go:"GO:0070181"(small ribosomal subunit rRNA binding)|go:"GO:1990932"(5.8S rRNA binding)|interpro:IPR000589(Ribosomal protein S15)|interpro:IPR009068(S15/NS1, RNA-binding)|interpro:IPR012606(Ribosomal protein S13/S15, N-terminal)|interpro:IPR023029|mint:P62278|reactome:R-RNO-156827|reactome:R-RNO-1799339|reactome:R-RNO-6791226|reactome:R-RNO-72649|reactome:R-RNO-72689|reactome:R-RNO-72695|reactome:R-RNO-72702|reactome:R-RNO-72706|reactome:R-RNO-975956|reactome:R-RNO-975957|refseq:XP_003753737.1	-	-	-	figure legend:st1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10116(rat-brain-cortex)|taxid:10116(Rattus norvegicus brain cortex)	-	2020/10/30	2020/10/30	rogid:DtE+ZXAZKdCMvUW5K+jXQ5bH07M10116	rogid:GmlWYkXKxX6YwpEtzNABb+ZcytI10116	rigid:3wclwrjZRvafcOruQOYnegkn54c	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q5XIE8	uniprotkb:Q4FZT9	intact:EBI-15348306|ensembl:ENSRNOP00000023037	intact:EBI-2640482|ensembl:ENSRNOP00000002358	psi-mi:itm2b_rat(display_long)|uniprotkb:Itm2b(gene name)|psi-mi:Itm2b(display_short)|uniprotkb:Immature BRI2(gene name synonym)|uniprotkb:Transmembrane protein BRI(gene name synonym)	psi-mi:psmd2_rat(display_long)|uniprotkb:Psmd2(gene name)|psi-mi:Psmd2(display_short)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Martins et al. (2018)	imex:IM-28469|pubmed:29476059	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26439741|imex:IM-28469-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSRNOG00000016271(gene)|ensembl:ENSRNOT00000023037(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001540"(amyloid-beta binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0010008"(endosome membrane)|go:"GO:0030660"(Golgi-associated vesicle membrane)|go:"GO:0031301"(integral component of organelle membrane)|go:"GO:0042985"(negative regulation of amyloid precursor protein biosynthetic process)|interpro:IPR007084(BRICHOS)|interpro:IPR040145|mint:Q5XIE8|refseq:NP_001006964.1|rgd:620727	rgd:1305752|refseq:NP_001026809.1|reactome:R-RNO-69601|reactome:R-RNO-75815|reactome:R-RNO-8852276|reactome:R-RNO-8951664|reactome:R-RNO-983168|reactome:R-RNO-8854050|reactome:R-RNO-8932339|reactome:R-RNO-8939236|reactome:R-RNO-8941858|reactome:R-RNO-8948751|ensembl:ENSRNOG00000001719(gene)|ensembl:ENSRNOT00000002358(transcript)|go:"GO:0000502"(proteasome complex)|go:"GO:0005634"(nucleus)|go:"GO:0005838"(proteasome regulatory particle)|go:"GO:0008540"(proteasome regulatory particle, base subcomplex)|go:"GO:0022624"(proteasome accessory complex)|go:"GO:0030234"(enzyme regulator activity)|go:"GO:0034515"(proteasome storage granule)|go:"GO:0042176"(regulation of protein catabolic process)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|interpro:IPR002015(Proteasome/cyclosome, regulatory subunit)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR016643(26S proteasome regulatory complex, non-ATPase subcomplex, Rpn1 subunit)|interpro:IPR040892|interpro:IPR041433|mint:Q4FZT9|rcsb pdb:6EPC|rcsb pdb:6EPD|rcsb pdb:6EPE|rcsb pdb:6EPF|reactome:R-RNO-1169091|reactome:R-RNO-1234176|reactome:R-RNO-1236978|reactome:R-RNO-174084|reactome:R-RNO-174154|reactome:R-RNO-174178|reactome:R-RNO-174184|reactome:R-RNO-187577|reactome:R-RNO-195253|reactome:R-RNO-2467813|reactome:R-RNO-349425|reactome:R-RNO-350562|reactome:R-RNO-382556|reactome:R-RNO-450408|reactome:R-RNO-4608870|reactome:R-RNO-4641257|reactome:R-RNO-4641258|reactome:R-RNO-5358346|reactome:R-RNO-5607761|reactome:R-RNO-5610780|reactome:R-RNO-5610785|reactome:R-RNO-5632684|reactome:R-RNO-5658442|reactome:R-RNO-5668541|reactome:R-RNO-5676590|reactome:R-RNO-5687128|reactome:R-RNO-5689603|reactome:R-RNO-5689880|reactome:R-RNO-6798695|reactome:R-RNO-68827|reactome:R-RNO-68949|reactome:R-RNO-69017|reactome:R-RNO-69481	-	-	-	figure legend:st1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10116(rat-brain-cortex)|taxid:10116(Rattus norvegicus brain cortex)	-	2020/10/30	2020/10/30	rogid:DtE+ZXAZKdCMvUW5K+jXQ5bH07M10116	rogid:RLdXL5kvmBPO1OIhqHL/NoXaeCo10116	rigid:3wclwrjZRvafcOruQOYnegkn54c	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q5XIE8	uniprotkb:P63081	intact:EBI-15348306|ensembl:ENSRNOP00000023037	intact:EBI-2025009|uniprotkb:P23967|ensembl:ENSRNOP00000008736	psi-mi:itm2b_rat(display_long)|uniprotkb:Itm2b(gene name)|psi-mi:Itm2b(display_short)|uniprotkb:Immature BRI2(gene name synonym)|uniprotkb:Transmembrane protein BRI(gene name synonym)	psi-mi:vatl_rat(display_long)|uniprotkb:Atp6v0c(gene name)|psi-mi:Atp6v0c(display_short)|uniprotkb:Atp6c(gene name synonym)|uniprotkb:Atp6l(gene name synonym)|uniprotkb:Atpl(gene name synonym)|uniprotkb:Vacuolar proton pump 16 kDa proteolipid subunit(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Martins et al. (2018)	imex:IM-28469|pubmed:29476059	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26439741|imex:IM-28469-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSRNOG00000016271(gene)|ensembl:ENSRNOT00000023037(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001540"(amyloid-beta binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0010008"(endosome membrane)|go:"GO:0030660"(Golgi-associated vesicle membrane)|go:"GO:0031301"(integral component of organelle membrane)|go:"GO:0042985"(negative regulation of amyloid precursor protein biosynthetic process)|interpro:IPR007084(BRICHOS)|interpro:IPR040145|mint:Q5XIE8|refseq:NP_001006964.1|rgd:620727	rgd:621394|refseq:NP_570836.1|refseq:XP_006245960.1|ensembl:ENSRNOG00000006542(gene)|ensembl:ENSRNOT00000008736(transcript)|go:"GO:0005764"(lysosome)|go:"GO:0005774"(vacuolar membrane)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030177"(positive regulation of Wnt signaling pathway)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0033179"(proton-transporting V-type ATPase, V0 domain)|go:"GO:0046961"(proton-transporting ATPase activity, rotational mechanism)|go:"GO:0070374"(positive regulation of ERK1 and ERK2 cascade)|go:"GO:1904093"(negative regulation of autophagic cell death)|interpro:IPR000245(ATPase, V0 complex, proteolipid subunit C,)|interpro:IPR002379(ATPase, F0/V0 complex, subunit C)|interpro:IPR011555(ATPase, V0 complex, proteolipid subunit C, eukaryotic)|interpro:IPR035921|mint:P63081|rcsb pdb:6VQ6|rcsb pdb:6VQ7|rcsb pdb:6VQ8|rcsb pdb:6VQC|rcsb pdb:6VQG|rcsb pdb:6VQH|reactome:R-RNO-1222556|reactome:R-RNO-6798695|reactome:R-RNO-77387|reactome:R-RNO-917977|reactome:R-RNO-9639288|reactome:R-RNO-983712	-	-	-	figure legend:st1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10116(rat-brain-cortex)|taxid:10116(Rattus norvegicus brain cortex)	-	2020/10/30	2020/10/30	rogid:DtE+ZXAZKdCMvUW5K+jXQ5bH07M10116	rogid:Qx4BtXXIXdTlTTWE3nBHM8kThHU10116	rigid:3wclwrjZRvafcOruQOYnegkn54c	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q5XIE8	uniprotkb:P25286	intact:EBI-15348306|ensembl:ENSRNOP00000023037	intact:EBI-2024887|intact:EBI-11702593	psi-mi:itm2b_rat(display_long)|uniprotkb:Itm2b(gene name)|psi-mi:Itm2b(display_short)|uniprotkb:Immature BRI2(gene name synonym)|uniprotkb:Transmembrane protein BRI(gene name synonym)	psi-mi:vpp1_rat(display_long)|uniprotkb:Atp6v0a1(gene name)|psi-mi:Atp6v0a1(display_short)|uniprotkb:Atp6n1(gene name synonym)|uniprotkb:Vpp1(gene name synonym)|uniprotkb:Vacuolar proton translocating ATPase 116 kDa subunit a isoform 1(gene name synonym)|uniprotkb:Clathrin-coated vesicle/synaptic vesicle proton pump 116 kDa subunit(gene name synonym)|uniprotkb:Vacuolar proton pump subunit 1(gene name synonym)|uniprotkb:Vacuolar adenosine triphosphatase subunit Ac116(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Martins et al. (2018)	imex:IM-28469|pubmed:29476059	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26439741|imex:IM-28469-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSRNOG00000016271(gene)|ensembl:ENSRNOT00000023037(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001540"(amyloid-beta binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0010008"(endosome membrane)|go:"GO:0030660"(Golgi-associated vesicle membrane)|go:"GO:0031301"(integral component of organelle membrane)|go:"GO:0042985"(negative regulation of amyloid precursor protein biosynthetic process)|interpro:IPR007084(BRICHOS)|interpro:IPR040145|mint:Q5XIE8|refseq:NP_001006964.1|rgd:620727	interpro:IPR026028|interpro:IPR002490(ATPase, V0/A0 complex, 116-kDa subunit)|rgd:68405|refseq:NP_113792.2|mint:P25286|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0007035"(vacuolar acidification)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0016241"(regulation of macroautophagy)|go:"GO:0016471"(vacuolar proton-transporting V-type ATPase complex)|go:"GO:0030285"(integral component of synaptic vesicle membrane)|go:"GO:0042470"(melanosome)|go:"GO:0043195"(terminal bouton)|go:"GO:0043229"(intracellular organelle)|go:"GO:0046961"(proton-transporting ATPase activity, rotational mechanism)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051117"(ATPase binding)|go:"GO:1901998"(toxin transport)|rcsb pdb:6VQ6|rcsb pdb:6VQ7|rcsb pdb:6VQ8|rcsb pdb:6VQC|rcsb pdb:6VQG|rcsb pdb:6VQH|rcsb pdb:6VQI|rcsb pdb:6VQJ|rcsb pdb:6VQK|reactome:R-RNO-1222556|reactome:R-RNO-6798695|reactome:R-RNO-77387|reactome:R-RNO-917977|reactome:R-RNO-983712|go:"GO:0000220"(vacuolar proton-transporting V-type ATPase, V0 domain)	-	-	-	figure legend:st1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10116(rat-brain-cortex)|taxid:10116(Rattus norvegicus brain cortex)	-	2020/10/30	2020/10/30	rogid:DtE+ZXAZKdCMvUW5K+jXQ5bH07M10116	rogid:M+mzcb5KThafTTcJpimDmH5I4fk10116	rigid:3wclwrjZRvafcOruQOYnegkn54c	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q5XIE8	uniprotkb:Q9R1Z0	intact:EBI-15348306|ensembl:ENSRNOP00000023037	intact:EBI-2255834|uniprotkb:Q6GSZ1|uniprotkb:Q9ESR2|uniprotkb:Q9JI31|uniprotkb:Q9WTU2	psi-mi:itm2b_rat(display_long)|uniprotkb:Itm2b(gene name)|psi-mi:Itm2b(display_short)|uniprotkb:Immature BRI2(gene name synonym)|uniprotkb:Transmembrane protein BRI(gene name synonym)	psi-mi:vdac3_rat(display_long)|uniprotkb:Vdac3(gene name)|psi-mi:Vdac3(display_short)|uniprotkb:Outer mitochondrial membrane protein porin 3(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Martins et al. (2018)	imex:IM-28469|pubmed:29476059	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26439741|imex:IM-28469-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSRNOG00000016271(gene)|ensembl:ENSRNOT00000023037(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001540"(amyloid-beta binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0010008"(endosome membrane)|go:"GO:0030660"(Golgi-associated vesicle membrane)|go:"GO:0031301"(integral component of organelle membrane)|go:"GO:0042985"(negative regulation of amyloid precursor protein biosynthetic process)|interpro:IPR007084(BRICHOS)|interpro:IPR040145|mint:Q5XIE8|refseq:NP_001006964.1|rgd:620727	rgd:621577|refseq:NP_112645.1|interpro:IPR001925(Porin, eukaryotic type)|interpro:IPR030271|interpro:IPR027246|mint:Q9R1Z0|interpro:IPR023614|go:"GO:0000166"(nucleotide binding)|go:"GO:0001662"(behavioral fear response)|go:"GO:0005739"(mitochondrion)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005791"(rough endoplasmic reticulum)|go:"GO:0007268"(chemical synaptic transmission)|go:"GO:0007270"(neuron-neuron synaptic transmission)|go:"GO:0007612"(learning)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0008308"(voltage-gated anion channel activity)|go:"GO:0015288"(porin activity)|go:"GO:0016020"(membrane)|go:"GO:0046930"(pore complex)|go:"GO:1902017"(regulation of cilium assembly)|reactome:R-RNO-5689880	-	-	-	figure legend:st1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10116(rat-brain-cortex)|taxid:10116(Rattus norvegicus brain cortex)	-	2020/10/30	2020/10/30	rogid:DtE+ZXAZKdCMvUW5K+jXQ5bH07M10116	rogid:32zwKuZVCTarCx4d4bMt6Apc6cE10116	rigid:3wclwrjZRvafcOruQOYnegkn54c	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q5XIE8	uniprotkb:Q9JJW3	intact:EBI-15348306|ensembl:ENSRNOP00000023037	intact:EBI-26437382|ensembl:ENSRNOP00000027496|ensembl:ENSRNOP00000061817	psi-mi:itm2b_rat(display_long)|uniprotkb:Itm2b(gene name)|psi-mi:Itm2b(display_short)|uniprotkb:Immature BRI2(gene name synonym)|uniprotkb:Transmembrane protein BRI(gene name synonym)	psi-mi:atpmk_rat(display_long)|uniprotkb:Atp5mk(gene name)|psi-mi:Atp5mk(display_short)|uniprotkb:ATP synthase membrane subunit DAPIT, mitochondrial(gene name synonym)|uniprotkb:Atp5md(gene name synonym)|uniprotkb:Dapit(gene name synonym)|uniprotkb:Diabetes-associated protein in insulin-sensitive tissues(gene name synonym)|uniprotkb:Up-regulated during skeletal muscle growth protein 5(gene name synonym)|uniprotkb:Usmg5(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Martins et al. (2018)	imex:IM-28469|pubmed:29476059	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26439741|imex:IM-28469-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSRNOG00000016271(gene)|ensembl:ENSRNOT00000023037(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001540"(amyloid-beta binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0010008"(endosome membrane)|go:"GO:0030660"(Golgi-associated vesicle membrane)|go:"GO:0031301"(integral component of organelle membrane)|go:"GO:0042985"(negative regulation of amyloid precursor protein biosynthetic process)|interpro:IPR007084(BRICHOS)|interpro:IPR040145|mint:Q5XIE8|refseq:NP_001006964.1|rgd:620727	ensembl:ENSRNOG00000020296(gene)|ensembl:ENSRNOG00000042869(gene)|ensembl:ENSRNOT00000027496(transcript)|ensembl:ENSRNOT00000064931(transcript)|go:"GO:0005739"(mitochondrion)|go:"GO:0005753"(mitochondrial proton-transporting ATP synthase complex)|go:"GO:0016021"(integral component of membrane)|interpro:IPR009125(DAPIT)|mint:Q9JJW3|refseq:NP_598228.1|refseq:XP_008766441.1|refseq:XP_008773622.1|rgd:631426	-	-	-	figure legend:st1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10116(rat-brain-cortex)|taxid:10116(Rattus norvegicus brain cortex)	-	2020/10/30	2020/10/30	rogid:DtE+ZXAZKdCMvUW5K+jXQ5bH07M10116	rogid:PeUvTdLYLEDd4wXYTYtUyyslllY10116	rigid:3wclwrjZRvafcOruQOYnegkn54c	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q5XIE8	uniprotkb:P11167	intact:EBI-15348306|ensembl:ENSRNOP00000023037	intact:EBI-960654|ensembl:ENSRNOP00000061340	psi-mi:itm2b_rat(display_long)|uniprotkb:Itm2b(gene name)|psi-mi:Itm2b(display_short)|uniprotkb:Immature BRI2(gene name synonym)|uniprotkb:Transmembrane protein BRI(gene name synonym)	psi-mi:gtr1_rat(display_long)|uniprotkb:Slc2a1(gene name)|psi-mi:Slc2a1(display_short)|uniprotkb:Glut1(gene name synonym)|uniprotkb:Glucose transporter type 1, erythrocyte/brain(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Martins et al. (2018)	imex:IM-28469|pubmed:29476059	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26439741|imex:IM-28469-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSRNOG00000016271(gene)|ensembl:ENSRNOT00000023037(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001540"(amyloid-beta binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0010008"(endosome membrane)|go:"GO:0030660"(Golgi-associated vesicle membrane)|go:"GO:0031301"(integral component of organelle membrane)|go:"GO:0042985"(negative regulation of amyloid precursor protein biosynthetic process)|interpro:IPR007084(BRICHOS)|interpro:IPR040145|mint:Q5XIE8|refseq:NP_001006964.1|rgd:620727	ensembl:ENSRNOG00000007284(gene)|ensembl:ENSRNOT00000064452(transcript)|go:"GO:0001666"(response to hypoxia)|go:"GO:0001917"(photoreceptor inner segment)|go:"GO:0001939"(female pronucleus)|go:"GO:0005324"(long-chain fatty acid transporter activity)|go:"GO:0005355"(glucose transmembrane transporter activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0005901"(caveola)|go:"GO:0005911"(cell-cell junction)|go:"GO:0006970"(response to osmotic stress)|go:"GO:0007417"(central nervous system development)|go:"GO:0007565"(female pregnancy)|go:"GO:0014704"(intercalated disc)|go:"GO:0015911"(long-chain fatty acid import across plasma membrane)|go:"GO:0016020"(membrane)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0019900"(kinase binding)|go:"GO:0021987"(cerebral cortex development)|go:"GO:0030018"(Z disc)|go:"GO:0030496"(midbody)|go:"GO:0030864"(cortical actin cytoskeleton)|go:"GO:0032868"(response to insulin)|go:"GO:0033300"(dehydroascorbic acid transmembrane transporter activity)|go:"GO:0042149"(cellular response to glucose starvation)|go:"GO:0042383"(sarcolemma)|go:"GO:0042802"(identical protein binding)|go:"GO:0042908"(xenobiotic transport)|go:"GO:0042910"(xenobiotic transmembrane transporter activity)|go:"GO:0043621"(protein self-association)|go:"GO:0045121"(membrane raft)|go:"GO:0031982"(vesicle)|go:"GO:0045202"(synapse)|go:"GO:0045494"(photoreceptor cell maintenance)|go:"GO:0055056"(D-glucose transmembrane transporter activity)|go:"GO:0065003"(protein-containing complex assembly)|go:"GO:0070837"(dehydroascorbic acid transport)|go:"GO:0071260"(cellular response to mechanical stimulus)|go:"GO:0071474"(cellular hyperosmotic response)|go:"GO:0098708"(glucose import across plasma membrane)|go:"GO:0098793"(presynapse)|go:"GO:0150104"(transport across blood-brain barrier)|go:"GO:1904016"(response to Thyroglobulin triiodothyronine)|go:"GO:1904659"(glucose transmembrane transport)|interpro:IPR002439("Glucose transporter, type 1 (GLUT1)")|interpro:IPR003663(Sugar transporter)|interpro:IPR005828(General substrate transporter)|interpro:IPR005829(Sugar transporter, conserved site)|interpro:IPR020846|interpro:IPR036259|mint:P11167|reactome:R-RNO-189200|reactome:R-RNO-422356|reactome:R-RNO-5653890|reactome:R-RNO-196836|rgd:3704|refseq:NP_620182.1	-	-	-	figure legend:st1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10116(rat-brain-cortex)|taxid:10116(Rattus norvegicus brain cortex)	-	2020/10/30	2020/10/30	rogid:DtE+ZXAZKdCMvUW5K+jXQ5bH07M10116	rogid:JriqkyQOrkEOA8WptfkF8G5sD2w10116	rigid:3wclwrjZRvafcOruQOYnegkn54c	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q5XIE8	uniprotkb:P13638	intact:EBI-15348306|ensembl:ENSRNOP00000023037	intact:EBI-26437335	psi-mi:itm2b_rat(display_long)|uniprotkb:Itm2b(gene name)|psi-mi:Itm2b(display_short)|uniprotkb:Immature BRI2(gene name synonym)|uniprotkb:Transmembrane protein BRI(gene name synonym)	psi-mi:at1b2_rat(display_long)|uniprotkb:Atp1b2(gene name)|psi-mi:Atp1b2(display_short)|uniprotkb:Sodium/potassium-dependent ATPase subunit beta-2(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Martins et al. (2018)	imex:IM-28469|pubmed:29476059	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26439741|imex:IM-28469-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSRNOG00000016271(gene)|ensembl:ENSRNOT00000023037(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001540"(amyloid-beta binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0010008"(endosome membrane)|go:"GO:0030660"(Golgi-associated vesicle membrane)|go:"GO:0031301"(integral component of organelle membrane)|go:"GO:0042985"(negative regulation of amyloid precursor protein biosynthetic process)|interpro:IPR007084(BRICHOS)|interpro:IPR040145|mint:Q5XIE8|refseq:NP_001006964.1|rgd:620727	go:"GO:0120036"(plasma membrane bounded cell projection organization)|go:"GO:1901018"(positive regulation of potassium ion transmembrane transporter activity)|go:"GO:1903278"(positive regulation of sodium ion export across plasma membrane)|go:"GO:1903288"(positive regulation of potassium ion import across plasma membrane)|go:"GO:1903976"(negative regulation of glial cell migration)|go:"GO:1990573"(potassium ion import across plasma membrane)|reactome:R-RNO-210991|reactome:R-RNO-5578775|reactome:R-RNO-936837|go:"GO:0098984"(neuron to neuron synapse)|go:"GO:0001671"(ATPase activator activity)|go:"GO:0001895"(retina homeostasis)|go:"GO:0001917"(photoreceptor inner segment)|go:"GO:0005391"("P-type sodium:potassium-exchanging transporter activity")|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0005890"("sodium:potassium-exchanging ATPase complex")|go:"GO:0006883"(cellular sodium ion homeostasis)|go:"GO:0009897"(external side of plasma membrane)|go:"GO:0010976"(positive regulation of neuron projection development)|go:"GO:0016020"(membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0016328"(lateral plasma membrane)|go:"GO:0021670"(lateral ventricle development)|go:"GO:0021678"(third ventricle development)|go:"GO:0021944"(neuronal-glial interaction involved in hindbrain glial-mediated radial cell migration)|go:"GO:0030007"(cellular potassium ion homeostasis)|go:"GO:0030674"(protein-macromolecule adaptor activity)|go:"GO:0031253"(cell projection membrane)|go:"GO:0031589"(cell-substrate adhesion)|go:"GO:0032781"(positive regulation of ATP-dependent activity)|go:"GO:0036376"(sodium ion export across plasma membrane)|go:"GO:0044298"(cell body membrane)|go:"GO:0045494"(photoreceptor cell maintenance)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0050821"(protein stabilization)|go:"GO:0051117"(ATPase binding)|go:"GO:0061744"(motor behavior)|go:"GO:0071944"(cell periphery)|go:"GO:0086009"(membrane repolarization)|go:"GO:0097449"(astrocyte projection)|go:"GO:0097450"(astrocyte end-foot)|mint:P13638|interpro:IPR000402(ATPase, P-type cation exchange, beta subunit)|interpro:IPR038702|rgd:2171	-	-	-	figure legend:st1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10116(rat-brain-cortex)|taxid:10116(Rattus norvegicus brain cortex)	-	2020/10/30	2020/10/30	rogid:DtE+ZXAZKdCMvUW5K+jXQ5bH07M10116	rogid:bl1sa8rfoB1To7Q5na/Mx5QU8Mw10116	rigid:3wclwrjZRvafcOruQOYnegkn54c	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q5XIE8	uniprotkb:P07340	intact:EBI-15348306|ensembl:ENSRNOP00000023037	intact:EBI-2640714|uniprotkb:Q63062|ensembl:ENSRNOP00000003932	psi-mi:itm2b_rat(display_long)|uniprotkb:Itm2b(gene name)|psi-mi:Itm2b(display_short)|uniprotkb:Immature BRI2(gene name synonym)|uniprotkb:Transmembrane protein BRI(gene name synonym)	psi-mi:at1b1_rat(display_long)|uniprotkb:Atp1b1(gene name)|psi-mi:Atp1b1(display_short)|uniprotkb:Sodium/potassium-dependent ATPase subunit beta-1(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Martins et al. (2018)	imex:IM-28469|pubmed:29476059	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26439741|imex:IM-28469-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSRNOG00000016271(gene)|ensembl:ENSRNOT00000023037(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001540"(amyloid-beta binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0010008"(endosome membrane)|go:"GO:0030660"(Golgi-associated vesicle membrane)|go:"GO:0031301"(integral component of organelle membrane)|go:"GO:0042985"(negative regulation of amyloid precursor protein biosynthetic process)|interpro:IPR007084(BRICHOS)|interpro:IPR040145|mint:Q5XIE8|refseq:NP_001006964.1|rgd:620727	rgd:2170|refseq:NP_037245.2|ensembl:ENSRNOG00000002934(gene)|ensembl:ENSRNOT00000003932(transcript)|go:"GO:0001666"(response to hypoxia)|go:"GO:0001671"(ATPase activator activity)|go:"GO:0001824"(blastocyst development)|go:"GO:0005391"("P-type sodium:potassium-exchanging transporter activity")|go:"GO:0005886"(plasma membrane)|go:"GO:0005890"("sodium:potassium-exchanging ATPase complex")|go:"GO:0005901"(caveola)|go:"GO:0006813"(potassium ion transport)|go:"GO:0006814"(sodium ion transport)|go:"GO:0006874"(cellular calcium ion homeostasis)|go:"GO:0006883"(cellular sodium ion homeostasis)|go:"GO:0007155"(cell adhesion)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0010882"(regulation of cardiac muscle contraction by calcium ion signaling)|go:"GO:0050821"(protein stabilization)|go:"GO:0051117"(ATPase binding)|go:"GO:0055119"(relaxation of cardiac muscle)|go:"GO:0060048"(cardiac muscle contraction)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0086009"(membrane repolarization)|go:"GO:0098655"(cation transmembrane transport)|go:"GO:1901018"(positive regulation of potassium ion transmembrane transporter activity)|go:"GO:1903169"(regulation of calcium ion transmembrane transport)|go:"GO:0014704"(intercalated disc)|go:"GO:0016020"(membrane)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0016328"(lateral plasma membrane)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030001"(metal ion transport)|go:"GO:1903278"(positive regulation of sodium ion export across plasma membrane)|go:"GO:0030007"(cellular potassium ion homeostasis)|go:"GO:1903281"("positive regulation of calcium:sodium antiporter activity")|go:"GO:1903288"(positive regulation of potassium ion import across plasma membrane)|go:"GO:0030315"(T-tubule)|go:"GO:1903408"("positive regulation of P-type sodium:potassium-exchanging transporter activity")|go:"GO:0030674"(protein-macromolecule adaptor activity)|go:"GO:0031090"(organelle membrane)|go:"GO:0032781"(positive regulation of ATP-dependent activity)|go:"GO:0035725"(sodium ion transmembrane transport)|go:"GO:0036126"(sperm flagellum)|go:"GO:0036376"(sodium ion export across plasma membrane)|go:"GO:0042383"(sarcolemma)|go:"GO:0046034"(ATP metabolic process)|go:"GO:0046982"(protein heterodimerization activity)|interpro:IPR000402(ATPase, P-type cation exchange, beta subunit)|interpro:IPR015565(Sodium/Potassium-Dependent ATPase Beta-1 Subunit)|interpro:IPR038702|mint:P07340|reactome:R-RNO-210991|reactome:R-RNO-5578775|reactome:R-RNO-936837|go:"GO:1990573"(potassium ion import across plasma membrane)	-	-	-	figure legend:st1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10116(rat-brain-cortex)|taxid:10116(Rattus norvegicus brain cortex)	-	2020/10/30	2020/10/30	rogid:DtE+ZXAZKdCMvUW5K+jXQ5bH07M10116	rogid:gJJ7PU6Tz3znT4wWy7GIPSV/x9w10116	rigid:3wclwrjZRvafcOruQOYnegkn54c	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q5XIE8	uniprotkb:P49432	intact:EBI-15348306|ensembl:ENSRNOP00000023037	intact:EBI-917663|uniprotkb:Q6AY95|ensembl:ENSRNOP00000010545	psi-mi:itm2b_rat(display_long)|uniprotkb:Itm2b(gene name)|psi-mi:Itm2b(display_short)|uniprotkb:Immature BRI2(gene name synonym)|uniprotkb:Transmembrane protein BRI(gene name synonym)	psi-mi:odpb_rat(display_long)|uniprotkb:Pdhb(gene name)|psi-mi:Pdhb(display_short)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Martins et al. (2018)	imex:IM-28469|pubmed:29476059	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26439741|imex:IM-28469-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSRNOG00000016271(gene)|ensembl:ENSRNOT00000023037(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001540"(amyloid-beta binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0010008"(endosome membrane)|go:"GO:0030660"(Golgi-associated vesicle membrane)|go:"GO:0031301"(integral component of organelle membrane)|go:"GO:0042985"(negative regulation of amyloid precursor protein biosynthetic process)|interpro:IPR007084(BRICHOS)|interpro:IPR040145|mint:Q5XIE8|refseq:NP_001006964.1|rgd:620727	rgd:1359146|refseq:NP_001007621.1|ensembl:ENSRNOG00000007895(gene)|ensembl:ENSRNOT00000010545(transcript)|go:"GO:0004739"("pyruvate dehydrogenase (acetyl-transferring) activity")|go:"GO:0005739"(mitochondrion)|go:"GO:0005967"(mitochondrial pyruvate dehydrogenase complex)|go:"GO:0006006"(glucose metabolic process)|go:"GO:0006086"(acetyl-CoA biosynthetic process from pyruvate)|go:"GO:0006099"(tricarboxylic acid cycle)|go:"GO:0045254"(pyruvate dehydrogenase complex)|interpro:IPR005475(Transketolase, central region)|interpro:IPR009014(Transketolase, C-terminal/Pyruvate-ferredoxin oxidoreductase, domain II)|interpro:IPR027110|interpro:IPR029061|interpro:IPR033248|mint:P49432|reactome:R-RNO-204174|reactome:R-RNO-389661|reactome:R-RNO-5362517|reactome:R-RNO-70268|refseq:XP_006251816.1	-	-	-	figure legend:st1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10116(rat-brain-cortex)|taxid:10116(Rattus norvegicus brain cortex)	-	2020/10/30	2020/10/30	rogid:DtE+ZXAZKdCMvUW5K+jXQ5bH07M10116	rogid:IauZD1wmQ+/x/0WJZxx7kyX8FT410116	rigid:3wclwrjZRvafcOruQOYnegkn54c	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q5XIE8	uniprotkb:Q66HF1	intact:EBI-15348306|ensembl:ENSRNOP00000023037	intact:EBI-21997221|ensembl:ENSRNOP00000015851	psi-mi:itm2b_rat(display_long)|uniprotkb:Itm2b(gene name)|psi-mi:Itm2b(display_short)|uniprotkb:Immature BRI2(gene name synonym)|uniprotkb:Transmembrane protein BRI(gene name synonym)	psi-mi:ndus1_rat(display_long)|uniprotkb:Ndufs1(gene name)|psi-mi:Ndufs1(display_short)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Martins et al. (2018)	imex:IM-28469|pubmed:29476059	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26439741|imex:IM-28469-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSRNOG00000016271(gene)|ensembl:ENSRNOT00000023037(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001540"(amyloid-beta binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0010008"(endosome membrane)|go:"GO:0030660"(Golgi-associated vesicle membrane)|go:"GO:0031301"(integral component of organelle membrane)|go:"GO:0042985"(negative regulation of amyloid precursor protein biosynthetic process)|interpro:IPR007084(BRICHOS)|interpro:IPR040145|mint:Q5XIE8|refseq:NP_001006964.1|rgd:620727	rgd:1359670|refseq:NP_001005550.1|ensembl:ENSRNOG00000011849(gene)|ensembl:ENSRNOT00000015852(transcript)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005747"(mitochondrial respiratory chain complex I)|go:"GO:0005758"(mitochondrial intermembrane space)|go:"GO:0006120"(mitochondrial electron transport, NADH to ubiquinone)|go:"GO:0008137"("NADH dehydrogenase (ubiquinone) activity")|go:"GO:0008637"(apoptotic mitochondrial changes)|go:"GO:0009055"(electron transfer activity)|go:"GO:0032981"(mitochondrial respiratory chain complex I assembly)|go:"GO:0045333"(cellular respiration)|go:"GO:0046034"(ATP metabolic process)|go:"GO:0046872"(metal ion binding)|go:"GO:0051537"(2 iron, 2 sulfur cluster binding)|go:"GO:0051539"(4 iron, 4 sulfur cluster binding)|go:"GO:0051881"(regulation of mitochondrial membrane potential)|go:"GO:0072593"(reactive oxygen species metabolic process)|interpro:IPR000283(NADH dehydrogenase 75 kDa subunit, conserved site)|interpro:IPR001041(Ferredoxin)|interpro:IPR006656(Molybdopterin oxidoreductase)|interpro:IPR006963(Molybdopterin oxidoreductase Fe4S4 region)|interpro:IPR010228(NADH-quinone oxidoreductase, chain G)|interpro:IPR015405(NADH-quinone oxidoreductase, chain G, C-terminal)|interpro:IPR019574|interpro:IPR036010|mint:Q66HF1|reactome:R-RNO-611105|reactome:R-RNO-6799198	-	-	-	figure legend:st1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10116(rat-brain-cortex)|taxid:10116(Rattus norvegicus brain cortex)	-	2020/10/30	2020/10/30	rogid:DtE+ZXAZKdCMvUW5K+jXQ5bH07M10116	rogid:rBq5pYwfc7co6OKLTc8OUF4jX1g10116	rigid:3wclwrjZRvafcOruQOYnegkn54c	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q5XIE8	uniprotkb:P97700	intact:EBI-15348306|ensembl:ENSRNOP00000023037	intact:EBI-918109	psi-mi:itm2b_rat(display_long)|uniprotkb:Itm2b(gene name)|psi-mi:Itm2b(display_short)|uniprotkb:Immature BRI2(gene name synonym)|uniprotkb:Transmembrane protein BRI(gene name synonym)	psi-mi:m2om_rat(display_long)|uniprotkb:Solute carrier family 25 member 11(gene name synonym)|uniprotkb:Slc25a11(gene name)|psi-mi:Slc25a11(display_short)|uniprotkb:Slc20a4(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Martins et al. (2018)	imex:IM-28469|pubmed:29476059	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26439741|imex:IM-28469-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSRNOG00000016271(gene)|ensembl:ENSRNOT00000023037(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001540"(amyloid-beta binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0010008"(endosome membrane)|go:"GO:0030660"(Golgi-associated vesicle membrane)|go:"GO:0031301"(integral component of organelle membrane)|go:"GO:0042985"(negative regulation of amyloid precursor protein biosynthetic process)|interpro:IPR007084(BRICHOS)|interpro:IPR040145|mint:Q5XIE8|refseq:NP_001006964.1|rgd:620727	rgd:708476|refseq:NP_071793.1|interpro:IPR018108|interpro:IPR023395|mint:P97700|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0008272"(sulfate transport)|go:"GO:0015116"(sulfate transmembrane transporter activity)|go:"GO:0015117"(thiosulfate transmembrane transporter activity)|go:"GO:0015131"(oxaloacetate transmembrane transporter activity)|go:"GO:0015139"(alpha-ketoglutarate transmembrane transporter activity)|go:"GO:0015140"(malate transmembrane transporter activity)|go:"GO:0015141"(succinate transmembrane transporter activity)|go:"GO:0015297"(antiporter activity)|go:"GO:0015709"(thiosulfate transport)|go:"GO:0015729"(oxaloacetate transport)|go:"GO:0016021"(integral component of membrane)|go:"GO:0035435"(phosphate ion transmembrane transport)|go:"GO:0071422"(succinate transmembrane transport)|go:"GO:0071423"(malate transmembrane transport)|reactome:R-RNO-70263	-	-	-	figure legend:st1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10116(rat-brain-cortex)|taxid:10116(Rattus norvegicus brain cortex)	-	2020/10/30	2020/10/30	rogid:DtE+ZXAZKdCMvUW5K+jXQ5bH07M10116	rogid:CwkgqsG6PQ93hzzwLedusjml4do10116	rigid:3wclwrjZRvafcOruQOYnegkn54c	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q5XIE8	uniprotkb:P04897	intact:EBI-15348306|ensembl:ENSRNOP00000023037	intact:EBI-915875|ensembl:ENSRNOP00000022550	psi-mi:itm2b_rat(display_long)|uniprotkb:Itm2b(gene name)|psi-mi:Itm2b(display_short)|uniprotkb:Immature BRI2(gene name synonym)|uniprotkb:Transmembrane protein BRI(gene name synonym)	psi-mi:gnai2_rat(display_long)|uniprotkb:Adenylate cyclase-inhibiting G alpha protein(gene name synonym)|uniprotkb:Gnai2(gene name)|psi-mi:Gnai2(display_short)|uniprotkb:Gnai-2(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Martins et al. (2018)	imex:IM-28469|pubmed:29476059	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26439741|imex:IM-28469-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSRNOG00000016271(gene)|ensembl:ENSRNOT00000023037(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001540"(amyloid-beta binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0010008"(endosome membrane)|go:"GO:0030660"(Golgi-associated vesicle membrane)|go:"GO:0031301"(integral component of organelle membrane)|go:"GO:0042985"(negative regulation of amyloid precursor protein biosynthetic process)|interpro:IPR007084(BRICHOS)|interpro:IPR040145|mint:Q5XIE8|refseq:NP_001006964.1|rgd:620727	rgd:620243|refseq:NP_112297.1|refseq:XP_006243920.1|dip:DIP-607N|ensembl:ENSRNOG00000016592(gene)|ensembl:ENSRNOT00000022550(transcript)|go:"GO:0001664"(G protein-coupled receptor binding)|go:"GO:0001973"(G protein-coupled adenosine receptor signaling pathway)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005834"(heterotrimeric G-protein complex)|go:"GO:0005886"(plasma membrane)|go:"GO:0007049"(cell cycle)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0007188"(adenylate cyclase-modulating G protein-coupled receptor signaling pathway)|go:"GO:0007189"(adenylate cyclase-activating G protein-coupled receptor signaling pathway)|go:"GO:0007193"(adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway)|go:"GO:0007213"(G protein-coupled acetylcholine receptor signaling pathway)|go:"GO:0007214"(gamma-aminobutyric acid signaling pathway)|go:"GO:0008283"(cell population proliferation)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0016020"(membrane)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0030425"(dendrite)|go:"GO:0030496"(midbody)|go:"GO:0031683"(G-protein beta/gamma-subunit complex binding)|go:"GO:0032930"(positive regulation of superoxide anion generation)|go:"GO:0033864"("positive regulation of NAD(P)H oxidase activity")|go:"GO:0035810"(positive regulation of urine volume)|go:"GO:0035815"(positive regulation of renal sodium excretion)|go:"GO:0044297"(cell body)|go:"GO:0045121"(membrane raft)|go:"GO:0045202"(synapse)|go:"GO:0045955"(negative regulation of calcium ion-dependent exocytosis)|go:"GO:0046628"(positive regulation of insulin receptor signaling pathway)|go:"GO:0046872"(metal ion binding)|go:"GO:0050805"(negative regulation of synaptic transmission)|go:"GO:0051301"(cell division)|go:"GO:0051924"(regulation of calcium ion transport)|go:"GO:0070374"(positive regulation of ERK1 and ERK2 cascade)|go:"GO:0140199"(negative regulation of adenylate cyclase-activating adrenergic receptor signaling pathway involved in heart process)|go:"GO:1903614"(negative regulation of protein tyrosine phosphatase activity)|go:"GO:1904707"(positive regulation of vascular associated smooth muscle cell proliferation)|go:"GO:2000179"(positive regulation of neural precursor cell proliferation)|go:"GO:2001234"(negative regulation of apoptotic signaling pathway)|interpro:IPR001019("Guanine nucleotide binding protein (G-protein), alpha subunit")|interpro:IPR001408(G-protein alpha subunit, group I)|interpro:IPR011025(G protein alpha subunit, helical insertion)|interpro:IPR027417|mint:P04897|reactome:R-RNO-170670|reactome:R-RNO-392170|reactome:R-RNO-400042|reactome:R-RNO-418594|reactome:R-RNO-9009391	-	-	-	figure legend:st1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10116(rat-brain-cortex)|taxid:10116(Rattus norvegicus brain cortex)	-	2020/10/30	2020/10/30	rogid:DtE+ZXAZKdCMvUW5K+jXQ5bH07M10116	rogid:TXAwhCxZGiWn/waR1XaK92nByh410116	rigid:3wclwrjZRvafcOruQOYnegkn54c	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q5XIE8	uniprotkb:Q68FX0	intact:EBI-15348306|ensembl:ENSRNOP00000023037	intact:EBI-1216909|ensembl:ENSRNOP00000009681	psi-mi:itm2b_rat(display_long)|uniprotkb:Itm2b(gene name)|psi-mi:Itm2b(display_short)|uniprotkb:Immature BRI2(gene name synonym)|uniprotkb:Transmembrane protein BRI(gene name synonym)	psi-mi:idh3b_rat(display_long)|uniprotkb:Idh3B(gene name)|psi-mi:Idh3B(display_short)|uniprotkb:Isocitric dehydrogenase subunit beta(gene name synonym)|uniprotkb:"NAD(+)-specific ICDH subunit beta"(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Martins et al. (2018)	imex:IM-28469|pubmed:29476059	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26439741|imex:IM-28469-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSRNOG00000016271(gene)|ensembl:ENSRNOT00000023037(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001540"(amyloid-beta binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0010008"(endosome membrane)|go:"GO:0030660"(Golgi-associated vesicle membrane)|go:"GO:0031301"(integral component of organelle membrane)|go:"GO:0042985"(negative regulation of amyloid precursor protein biosynthetic process)|interpro:IPR007084(BRICHOS)|interpro:IPR040145|mint:Q5XIE8|refseq:NP_001006964.1|rgd:620727	rgd:621881|refseq:NP_446033.1|go:"GO:0006099"(tricarboxylic acid cycle)|go:"GO:0006102"(isocitrate metabolic process)|go:"GO:0006103"(2-oxoglutarate metabolic process)|go:"GO:0006734"(NADH metabolic process)|go:"GO:0051287"(NAD binding)|interpro:IPR004434(Isocitrate dehydrogenase NAD-dependent, mitochondrial)|interpro:IPR019818|interpro:IPR024084|mint:Q68FX0|reactome:R-RNO-71403|ensembl:ENSRNOG00000007316(gene)|ensembl:ENSRNOT00000009681(transcript)|go:"GO:0000287"(magnesium ion binding)|go:"GO:0004449"("isocitrate dehydrogenase (NAD+) activity")|go:"GO:0005739"(mitochondrion)|go:"GO:0005962"("mitochondrial isocitrate dehydrogenase complex (NAD+)")	-	-	-	figure legend:st1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10116(rat-brain-cortex)|taxid:10116(Rattus norvegicus brain cortex)	-	2020/10/30	2020/10/30	rogid:DtE+ZXAZKdCMvUW5K+jXQ5bH07M10116	rogid:DAPnk1qn2Ksoy7kcoPBWiiBcwTQ10116	rigid:3wclwrjZRvafcOruQOYnegkn54c	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q5XIE8	uniprotkb:P81155	intact:EBI-15348306|ensembl:ENSRNOP00000023037	intact:EBI-918064|uniprotkb:Q9JI32|ensembl:ENSRNOP00000018462|ensembl:ENSRNOP00000074839	psi-mi:itm2b_rat(display_long)|uniprotkb:Itm2b(gene name)|psi-mi:Itm2b(display_short)|uniprotkb:Immature BRI2(gene name synonym)|uniprotkb:Transmembrane protein BRI(gene name synonym)	psi-mi:vdac2_rat(display_long)|uniprotkb:Outer mitochondrial membrane protein porin 2(gene name synonym)|uniprotkb:B36-VDAC(gene name synonym)|uniprotkb:Vdac2(gene name)|psi-mi:Vdac2(display_short)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Martins et al. (2018)	imex:IM-28469|pubmed:29476059	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26439741|imex:IM-28469-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSRNOG00000016271(gene)|ensembl:ENSRNOT00000023037(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001540"(amyloid-beta binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0010008"(endosome membrane)|go:"GO:0030660"(Golgi-associated vesicle membrane)|go:"GO:0031301"(integral component of organelle membrane)|go:"GO:0042985"(negative regulation of amyloid precursor protein biosynthetic process)|interpro:IPR007084(BRICHOS)|interpro:IPR040145|mint:Q5XIE8|refseq:NP_001006964.1|rgd:620727	rgd:621576|refseq:NP_112644.1|refseq:XP_006251723.1|ensembl:ENSRNOG00000013505(gene)|ensembl:ENSRNOT00000018462(transcript)|ensembl:ENSRNOT00000086864(transcript)|go:"GO:0000166"(nucleotide binding)|go:"GO:0001669"(acrosomal vesicle)|go:"GO:0005739"(mitochondrion)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0006820"(anion transport)|go:"GO:0007339"(binding of sperm to zona pellucida)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0008308"(voltage-gated anion channel activity)|go:"GO:0015288"(porin activity)|go:"GO:0015485"(cholesterol binding)|go:"GO:0016020"(membrane)|go:"GO:0031210"(phosphatidylcholine binding)|go:"GO:0031966"(mitochondrial membrane)|go:"GO:0032272"(negative regulation of protein polymerization)|go:"GO:0042645"(mitochondrial nucleoid)|go:"GO:0046930"(pore complex)|go:"GO:0097001"(ceramide binding)|go:"GO:0097345"(mitochondrial outer membrane permeabilization)|go:"GO:2001243"(negative regulation of intrinsic apoptotic signaling pathway)|interpro:IPR001925(Porin, eukaryotic type)|interpro:IPR023614|interpro:IPR027246|interpro:IPR030277|mint:P81155|reactome:R-RNO-5689880	-	-	-	figure legend:st1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10116(rat-brain-cortex)|taxid:10116(Rattus norvegicus brain cortex)	-	2020/10/30	2020/10/30	rogid:DtE+ZXAZKdCMvUW5K+jXQ5bH07M10116	rogid:4hSm4QQy24guxjuUCy/7W97UqL810116	rigid:3wclwrjZRvafcOruQOYnegkn54c	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q5XIE8	uniprotkb:Q9Z2L0	intact:EBI-15348306|ensembl:ENSRNOP00000023037	intact:EBI-920336|uniprotkb:A1L125|uniprotkb:Q3MHT8|uniprotkb:Q5M944|uniprotkb:Q5M972|uniprotkb:Q6IN28|uniprotkb:Q6P9W9|ensembl:ENSRNOP00000008477	psi-mi:itm2b_rat(display_long)|uniprotkb:Itm2b(gene name)|psi-mi:Itm2b(display_short)|uniprotkb:Immature BRI2(gene name synonym)|uniprotkb:Transmembrane protein BRI(gene name synonym)	psi-mi:vdac1_rat(display_long)|uniprotkb:Vdac1(gene name)|psi-mi:Vdac1(display_short)|uniprotkb:Outer mitochondrial membrane protein porin 1(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Martins et al. (2018)	imex:IM-28469|pubmed:29476059	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26439741|imex:IM-28469-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSRNOG00000016271(gene)|ensembl:ENSRNOT00000023037(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001540"(amyloid-beta binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0010008"(endosome membrane)|go:"GO:0030660"(Golgi-associated vesicle membrane)|go:"GO:0031301"(integral component of organelle membrane)|go:"GO:0042985"(negative regulation of amyloid precursor protein biosynthetic process)|interpro:IPR007084(BRICHOS)|interpro:IPR040145|mint:Q5XIE8|refseq:NP_001006964.1|rgd:620727	rgd:621575|refseq:NP_112643.1|ensembl:ENSRNOG00000006375(gene)|ensembl:ENSRNOT00000008477(transcript)|go:"GO:0000166"(nucleotide binding)|go:"GO:0001662"(behavioral fear response)|go:"GO:0032991"(protein-containing complex)|go:"GO:0042645"(mitochondrial nucleoid)|go:"GO:0042802"(identical protein binding)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045121"(membrane raft)|go:"GO:0097001"(ceramide binding)|go:"GO:0110099"(negative regulation of calcium import into the mitochondrion)|go:"GO:1901526"(positive regulation of mitophagy)|go:"GO:1903146"(regulation of autophagy of mitochondrion)|go:"GO:2000378"(negative regulation of reactive oxygen species metabolic process)|interpro:IPR001925(Porin, eukaryotic type)|interpro:IPR023614|interpro:IPR027246|interpro:IPR030270|mint:Q9Z2L0|reactome:R-RNO-5205685|reactome:R-RNO-5689880|reactome:R-RNO-70268|go:"GO:0031966"(mitochondrial membrane)|go:"GO:0005253"(anion channel activity)|go:"GO:0005262"(calcium channel activity)|go:"GO:0005739"(mitochondrion)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005757"(mitochondrial permeability transition pore complex)|go:"GO:0005886"(plasma membrane)|go:"GO:0006820"(anion transport)|go:"GO:0006851"(mitochondrial calcium ion transmembrane transport)|go:"GO:0006915"(apoptotic process)|go:"GO:0007268"(chemical synaptic transmission)|go:"GO:0007270"(neuron-neuron synaptic transmission)|go:"GO:0007612"(learning)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0008308"(voltage-gated anion channel activity)|go:"GO:0015288"(porin activity)|go:"GO:0015485"(cholesterol binding)|go:"GO:0016020"(membrane)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030855"(epithelial cell differentiation)|go:"GO:0031210"(phosphatidylcholine binding)|dip:DIP-37068N	-	-	-	figure legend:st1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10116(rat-brain-cortex)|taxid:10116(Rattus norvegicus brain cortex)	-	2020/10/30	2020/10/30	rogid:DtE+ZXAZKdCMvUW5K+jXQ5bH07M10116	rogid:9tTXatzG8BVX217+t0HLppj0oAY10116	rigid:3wclwrjZRvafcOruQOYnegkn54c	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q5XIE8	uniprotkb:P0DJJ3	intact:EBI-15348306|ensembl:ENSRNOP00000023037	intact:EBI-26439465	psi-mi:itm2b_rat(display_long)|uniprotkb:Itm2b(gene name)|psi-mi:Itm2b(display_short)|uniprotkb:Immature BRI2(gene name synonym)|uniprotkb:Transmembrane protein BRI(gene name synonym)	psi-mi:sgip1_rat(display_long)|uniprotkb:Sgip1(gene name)|psi-mi:Sgip1(display_short)|uniprotkb:Endophilin-3-interacting protein(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Martins et al. (2018)	imex:IM-28469|pubmed:29476059	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26439741|imex:IM-28469-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSRNOG00000016271(gene)|ensembl:ENSRNOT00000023037(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001540"(amyloid-beta binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0010008"(endosome membrane)|go:"GO:0030660"(Golgi-associated vesicle membrane)|go:"GO:0031301"(integral component of organelle membrane)|go:"GO:0042985"(negative regulation of amyloid precursor protein biosynthetic process)|interpro:IPR007084(BRICHOS)|interpro:IPR040145|mint:Q5XIE8|refseq:NP_001006964.1|rgd:620727	go:"GO:0002021"(response to dietary excess)|go:"GO:0005543"(phospholipid binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0005905"(clathrin-coated pit)|go:"GO:0008017"(microtubule binding)|go:"GO:0015631"(tubulin binding)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0030122"(AP-2 adaptor complex)|go:"GO:0030136"(clathrin-coated vesicle)|go:"GO:0040018"(positive regulation of multicellular organism growth)|go:"GO:0042594"(response to starvation)|go:"GO:0043195"(terminal bouton)|go:"GO:0048260"(positive regulation of receptor-mediated endocytosis)|go:"GO:0048268"(clathrin coat assembly)|go:"GO:0072583"(clathrin-dependent endocytosis)|go:"GO:0097009"(energy homeostasis)|go:"GO:0098793"(presynapse)|go:"GO:1904000"(positive regulation of eating behavior)|go:"GO:2000253"(positive regulation of feeding behavior)|reactome:R-RNO-8856825|reactome:R-RNO-8856828|mint:P0DJJ3|refseq:XP_017449253.1|refseq:XP_017458523.1|interpro:IPR036168|interpro:IPR028565|interpro:IPR018808|interpro:IPR037984|rgd:1564957	-	-	-	figure legend:st1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10116(rat-brain-cortex)|taxid:10116(Rattus norvegicus brain cortex)	-	2020/10/30	2020/10/30	rogid:DtE+ZXAZKdCMvUW5K+jXQ5bH07M10116	rogid:J+vwy1Z+IAnYPPGLWNgA3SnnDzE10116	rigid:3wclwrjZRvafcOruQOYnegkn54c	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q5XIE8	uniprotkb:Q99NA5	intact:EBI-15348306|ensembl:ENSRNOP00000023037	intact:EBI-919767	psi-mi:itm2b_rat(display_long)|uniprotkb:Itm2b(gene name)|psi-mi:Itm2b(display_short)|uniprotkb:Immature BRI2(gene name synonym)|uniprotkb:Transmembrane protein BRI(gene name synonym)	psi-mi:idh3a_rat(display_long)|uniprotkb:Idh3a(gene name)|psi-mi:Idh3a(display_short)|uniprotkb:Isocitric dehydrogenase subunit alpha(gene name synonym)|uniprotkb:"NAD(+)-specific ICDH subunit alpha"(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Martins et al. (2018)	imex:IM-28469|pubmed:29476059	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26439741|imex:IM-28469-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSRNOG00000016271(gene)|ensembl:ENSRNOT00000023037(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001540"(amyloid-beta binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0010008"(endosome membrane)|go:"GO:0030660"(Golgi-associated vesicle membrane)|go:"GO:0031301"(integral component of organelle membrane)|go:"GO:0042985"(negative regulation of amyloid precursor protein biosynthetic process)|interpro:IPR007084(BRICHOS)|interpro:IPR040145|mint:Q5XIE8|refseq:NP_001006964.1|rgd:620727	rgd:70889|refseq:NP_446090.1|interpro:IPR019818|interpro:IPR004434(Isocitrate dehydrogenase NAD-dependent, mitochondrial)|interpro:IPR024084|mint:Q99NA5|go:"GO:0000287"(magnesium ion binding)|go:"GO:0004449"("isocitrate dehydrogenase (NAD+) activity")|go:"GO:0005739"(mitochondrion)|go:"GO:0005962"("mitochondrial isocitrate dehydrogenase complex (NAD+)")|go:"GO:0006099"(tricarboxylic acid cycle)|go:"GO:0006102"(isocitrate metabolic process)|go:"GO:0006103"(2-oxoglutarate metabolic process)|go:"GO:0006734"(NADH metabolic process)|go:"GO:0051287"(NAD binding)|reactome:R-RNO-71403	-	-	-	figure legend:st1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10116(rat-brain-cortex)|taxid:10116(Rattus norvegicus brain cortex)	-	2020/10/30	2020/10/30	rogid:DtE+ZXAZKdCMvUW5K+jXQ5bH07M10116	rogid:hwr6FxZD9vcrVjwYX/Qoty2o6ME10116	rigid:3wclwrjZRvafcOruQOYnegkn54c	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q5XIE8	uniprotkb:P19627	intact:EBI-15348306|ensembl:ENSRNOP00000023037	intact:EBI-26439434|ensembl:ENSRNOP00000001779	psi-mi:itm2b_rat(display_long)|uniprotkb:Itm2b(gene name)|psi-mi:Itm2b(display_short)|uniprotkb:Immature BRI2(gene name synonym)|uniprotkb:Transmembrane protein BRI(gene name synonym)	psi-mi:gnaz_rat(display_long)|uniprotkb:Gnaz(gene name)|psi-mi:Gnaz(display_short)|uniprotkb:"G(x) alpha chain"(gene name synonym)|uniprotkb:Gz-alpha(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Martins et al. (2018)	imex:IM-28469|pubmed:29476059	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26439741|imex:IM-28469-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSRNOG00000016271(gene)|ensembl:ENSRNOT00000023037(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001540"(amyloid-beta binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0010008"(endosome membrane)|go:"GO:0030660"(Golgi-associated vesicle membrane)|go:"GO:0031301"(integral component of organelle membrane)|go:"GO:0042985"(negative regulation of amyloid precursor protein biosynthetic process)|interpro:IPR007084(BRICHOS)|interpro:IPR040145|mint:Q5XIE8|refseq:NP_001006964.1|rgd:620727	ensembl:ENSRNOG00000001313(gene)|ensembl:ENSRNOT00000001779(transcript)|go:"GO:0001664"(G protein-coupled receptor binding)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005829"(cytosol)|go:"GO:0005834"(heterotrimeric G-protein complex)|go:"GO:0005886"(plasma membrane)|go:"GO:0007188"(adenylate cyclase-modulating G protein-coupled receptor signaling pathway)|go:"GO:0007193"(adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway)|go:"GO:0030425"(dendrite)|go:"GO:0031683"(G-protein beta/gamma-subunit complex binding)|go:"GO:0031821"(G protein-coupled serotonin receptor binding)|go:"GO:0044297"(cell body)|go:"GO:0046872"(metal ion binding)|go:"GO:0098664"(G protein-coupled serotonin receptor signaling pathway)|interpro:IPR001019("Guanine nucleotide binding protein (G-protein), alpha subunit")|interpro:IPR001408(G-protein alpha subunit, group I)|interpro:IPR011025(G protein alpha subunit, helical insertion)|interpro:IPR027417|mint:P19627|reactome:R-RNO-418597|refseq:NP_037321.1|refseq:XP_008771088.1|refseq:XP_008771089.1|refseq:XP_017457054.1|rgd:2717	-	-	-	figure legend:st1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10116(rat-brain-cortex)|taxid:10116(Rattus norvegicus brain cortex)	-	2020/10/30	2020/10/30	rogid:DtE+ZXAZKdCMvUW5K+jXQ5bH07M10116	rogid:fvi2QLvjnF52AQ7u5rw43TKLcQU10116	rigid:3wclwrjZRvafcOruQOYnegkn54c	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q5XIE8	uniprotkb:P10824	intact:EBI-15348306|ensembl:ENSRNOP00000023037	intact:EBI-1026411|uniprotkb:Q45QN2|ensembl:ENSRNOP00000074036	psi-mi:itm2b_rat(display_long)|uniprotkb:Itm2b(gene name)|psi-mi:Itm2b(display_short)|uniprotkb:Immature BRI2(gene name synonym)|uniprotkb:Transmembrane protein BRI(gene name synonym)	psi-mi:gnai1_rat(display_long)|uniprotkb:Adenylate cyclase-inhibiting G alpha protein(gene name synonym)|uniprotkb:Gnai1(gene name)|psi-mi:Gnai1(display_short)|uniprotkb:Gnai-1(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Martins et al. (2018)	imex:IM-28469|pubmed:29476059	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26439741|imex:IM-28469-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSRNOG00000016271(gene)|ensembl:ENSRNOT00000023037(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001540"(amyloid-beta binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0010008"(endosome membrane)|go:"GO:0030660"(Golgi-associated vesicle membrane)|go:"GO:0031301"(integral component of organelle membrane)|go:"GO:0042985"(negative regulation of amyloid precursor protein biosynthetic process)|interpro:IPR007084(BRICHOS)|interpro:IPR040145|mint:Q5XIE8|refseq:NP_001006964.1|rgd:620727	rgd:2713|refseq:NP_037277.1|ensembl:ENSRNOG00000057096(gene)|ensembl:ENSRNOT00000091004(transcript)|go:"GO:0000287"(magnesium ion binding)|go:"GO:0001664"(G protein-coupled receptor binding)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005834"(heterotrimeric G-protein complex)|go:"GO:0005886"(plasma membrane)|go:"GO:0007049"(cell cycle)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0007188"(adenylate cyclase-modulating G protein-coupled receptor signaling pathway)|go:"GO:0016020"(membrane)|go:"GO:0019003"(GDP binding)|go:"GO:0030496"(midbody)|go:"GO:0031683"(G-protein beta/gamma-subunit complex binding)|go:"GO:0031821"(G protein-coupled serotonin receptor binding)|go:"GO:0032794"(GTPase activating protein binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0043949"(regulation of cAMP-mediated signaling)|go:"GO:0045121"(membrane raft)|go:"GO:0050805"(negative regulation of synaptic transmission)|go:"GO:0051301"(cell division)|go:"GO:0060236"(regulation of mitotic spindle organization)|go:"GO:0099738"(cell cortex region)|go:"GO:1904322"(cellular response to forskolin)|go:"GO:1904778"(positive regulation of protein localization to cell cortex)|interpro:IPR001019("Guanine nucleotide binding protein (G-protein), alpha subunit")|interpro:IPR001408(G-protein alpha subunit, group I)|interpro:IPR011025(G protein alpha subunit, helical insertion)|interpro:IPR027417|mint:P10824|rcsb pdb:1AGR|rcsb pdb:1AS0|go:"GO:0005634"(nucleus)|rcsb pdb:1AS2|rcsb pdb:1BH2|rcsb pdb:1BOF|rcsb pdb:1CIP|rcsb pdb:1FQJ|rcsb pdb:1FQK|rcsb pdb:1GDD|rcsb pdb:1GFI|rcsb pdb:1GG2|rcsb pdb:1GIA|rcsb pdb:1GIL|rcsb pdb:1GIT|rcsb pdb:1GP2|rcsb pdb:1SHZ|rcsb pdb:1SVK|rcsb pdb:1SVS|rcsb pdb:2BCJ|rcsb pdb:2ZJY|rcsb pdb:2ZJZ|rcsb pdb:3AH8|rcsb pdb:3D7M|rcsb pdb:3FFA|rcsb pdb:3FFB|rcsb pdb:3V00|rcsb pdb:4N0D|rcsb pdb:4N0E|rcsb pdb:4PAM|rcsb pdb:4PAN|rcsb pdb:4PAO|rcsb pdb:4PAQ|rcsb pdb:5KDL|rcsb pdb:5KDO|rcsb pdb:6M8H|rcsb pdb:6TYL|rcsb pdb:6UKT|rcsb pdb:6VMS|reactome:R-RNO-170670|reactome:R-RNO-392170|reactome:R-RNO-400042|reactome:R-RNO-418594|reactome:R-RNO-9009391|rcsb pdb:1AS3|dip:DIP-6073N	-	-	-	figure legend:st1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10116(rat-brain-cortex)|taxid:10116(Rattus norvegicus brain cortex)	-	2020/10/30	2020/10/30	rogid:DtE+ZXAZKdCMvUW5K+jXQ5bH07M10116	rogid:4L9LLDHqr9N7S/GgFjFkDvaUQuY10116	rigid:3wclwrjZRvafcOruQOYnegkn54c	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q5XIE8	uniprotkb:P54311	intact:EBI-15348306|ensembl:ENSRNOP00000023037	intact:EBI-917779|uniprotkb:Q6Q8B1|uniprotkb:Q9QWG8|ensembl:ENSRNOP00000044340	psi-mi:itm2b_rat(display_long)|uniprotkb:Itm2b(gene name)|psi-mi:Itm2b(display_short)|uniprotkb:Immature BRI2(gene name synonym)|uniprotkb:Transmembrane protein BRI(gene name synonym)	psi-mi:gbb1_rat(display_long)|uniprotkb:Transducin beta chain 1(gene name synonym)|uniprotkb:Gnb1(gene name)|psi-mi:Gnb1(display_short)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Martins et al. (2018)	imex:IM-28469|pubmed:29476059	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26439741|imex:IM-28469-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSRNOG00000016271(gene)|ensembl:ENSRNOT00000023037(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001540"(amyloid-beta binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0010008"(endosome membrane)|go:"GO:0030660"(Golgi-associated vesicle membrane)|go:"GO:0031301"(integral component of organelle membrane)|go:"GO:0042985"(negative regulation of amyloid precursor protein biosynthetic process)|interpro:IPR007084(BRICHOS)|interpro:IPR040145|mint:Q5XIE8|refseq:NP_001006964.1|rgd:620727	rgd:2718|refseq:NP_112249.2|go:"GO:0001750"(photoreceptor outer segment)|go:"GO:0001917"(photoreceptor inner segment)|go:"GO:0003924"(GTPase activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005834"(heterotrimeric G-protein complex)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0007200"(phospholipase C-activating G protein-coupled receptor signaling pathway)|go:"GO:0007204"(positive regulation of cytosolic calcium ion concentration)|go:"GO:0008283"(cell population proliferation)|go:"GO:0010659"(cardiac muscle cell apoptotic process)|go:"GO:0030425"(dendrite)|go:"GO:0030507"(spectrin binding)|go:"GO:0031682"(G-protein gamma-subunit binding)|go:"GO:0042622"(photoreceptor outer segment membrane)|go:"GO:0044297"(cell body)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0047391"(alkylglycerophosphoethanolamine phosphodiesterase activity)|go:"GO:0050909"(sensory perception of taste)|ensembl:ENSRNOT00000041789(transcript)|ensembl:ENSRNOG00000016638(gene)|refseq:XP_008762557.1|refseq:XP_006239579.1|refseq:XP_017448634.1|refseq:XP_017448635.1|refseq:XP_017448636.1|refseq:XP_017448637.1|refseq:XP_017448638.1|dip:DIP-37029N|go:"GO:0051020"(GTPase binding)|go:"GO:0060041"(retina development in camera-type eye)|go:"GO:0071456"(cellular response to hypoxia)|interpro:IPR001632(G-protein, beta subunit)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR016346(Guanine nucleotide-binding protein, beta subunit)|interpro:IPR019775|interpro:IPR020472|interpro:IPR036322|mint:P54311|rcsb pdb:3SN6|rcsb pdb:5TDH|rcsb pdb:5VAI|rcsb pdb:6CMO|rcsb pdb:6LPB|rcsb pdb:6NBF|rcsb pdb:6NBH|rcsb pdb:6NBI|rcsb pdb:6WWZ|rcsb pdb:7BW0|rcsb pdb:7CZ5|rcsb pdb:7D3S|rcsb pdb:7LJC|rcsb pdb:7LJD|rcsb pdb:7MBX|rcsb pdb:7MBY|reactome:R-RNO-1296041|reactome:R-RNO-202040|reactome:R-RNO-2485179|reactome:R-RNO-381676|reactome:R-RNO-381753|reactome:R-RNO-392170|reactome:R-RNO-392451|reactome:R-RNO-400042|reactome:R-RNO-4086398|reactome:R-RNO-416476|reactome:R-RNO-418594|reactome:R-RNO-418597|reactome:R-RNO-420092|reactome:R-RNO-428930|reactome:R-RNO-432040|reactome:R-RNO-456926|reactome:R-RNO-6814122|reactome:R-RNO-8964616|reactome:R-RNO-997272	-	-	-	figure legend:st1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10116(rat-brain-cortex)|taxid:10116(Rattus norvegicus brain cortex)	-	2020/10/30	2020/10/30	rogid:DtE+ZXAZKdCMvUW5K+jXQ5bH07M10116	rogid:zP/G70MXiSQpzbyyWFTWrJFQENk10116	rigid:3wclwrjZRvafcOruQOYnegkn54c	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q5XIE8	uniprotkb:P10888	intact:EBI-15348306|ensembl:ENSRNOP00000023037	intact:EBI-916287|ensembl:ENSRNOP00000024033	psi-mi:itm2b_rat(display_long)|uniprotkb:Itm2b(gene name)|psi-mi:Itm2b(display_short)|uniprotkb:Immature BRI2(gene name synonym)|uniprotkb:Transmembrane protein BRI(gene name synonym)	psi-mi:cox41_rat(display_long)|uniprotkb:Cox4i1(gene name)|psi-mi:Cox4i1(display_short)|uniprotkb:Cox4(gene name synonym)|uniprotkb:Cox4a(gene name synonym)|uniprotkb:Cytochrome c oxidase subunit IV isoform 1(gene name synonym)|uniprotkb:Cytochrome c oxidase polypeptide IV(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Martins et al. (2018)	imex:IM-28469|pubmed:29476059	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26439741|imex:IM-28469-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSRNOG00000016271(gene)|ensembl:ENSRNOT00000023037(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001540"(amyloid-beta binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0010008"(endosome membrane)|go:"GO:0030660"(Golgi-associated vesicle membrane)|go:"GO:0031301"(integral component of organelle membrane)|go:"GO:0042985"(negative regulation of amyloid precursor protein biosynthetic process)|interpro:IPR007084(BRICHOS)|interpro:IPR040145|mint:Q5XIE8|refseq:NP_001006964.1|rgd:620727	rgd:68374|refseq:NP_058898.1|ensembl:ENSRNOG00000017817(gene)|ensembl:ENSRNOT00000024033(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005751"(mitochondrial respiratory chain complex IV)|go:"GO:0005829"(cytosol)|go:"GO:0006123"(mitochondrial electron transport, cytochrome c to oxygen)|go:"GO:0007584"(response to nutrient)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016491"(oxidoreductase activity)|go:"GO:0031966"(mitochondrial membrane)|interpro:IPR004203(Cytochrome c oxidase subunit IV)|interpro:IPR013288(Cytochrome c oxidase subunit 4)|interpro:IPR036639|mint:P10888|reactome:R-RNO-5628897|reactome:R-RNO-611105|reactome:R-RNO-9707564	-	-	-	figure legend:st1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10116(rat-brain-cortex)|taxid:10116(Rattus norvegicus brain cortex)	-	2020/10/30	2020/10/30	rogid:DtE+ZXAZKdCMvUW5K+jXQ5bH07M10116	rogid:tNIBFX8yX4FTJHKAMI9P5dGA5hE10116	rigid:3wclwrjZRvafcOruQOYnegkn54c	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q5XIE8	uniprotkb:Q9WVK7	intact:EBI-15348306|ensembl:ENSRNOP00000023037	intact:EBI-920220|ensembl:ENSRNOP00000014658	psi-mi:itm2b_rat(display_long)|uniprotkb:Itm2b(gene name)|psi-mi:Itm2b(display_short)|uniprotkb:Immature BRI2(gene name synonym)|uniprotkb:Transmembrane protein BRI(gene name synonym)	psi-mi:hcdh_rat(display_long)|uniprotkb:Hadh(gene name)|psi-mi:Hadh(display_short)|uniprotkb:Had(gene name synonym)|uniprotkb:Schad(gene name synonym)|uniprotkb:Short-chain 3-hydroxyacyl-CoA dehydrogenase(gene name synonym)|uniprotkb:Medium and short-chain L-3-hydroxyacyl-coenzyme A dehydrogenase(gene name synonym)|uniprotkb:Hadhsc(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Martins et al. (2018)	imex:IM-28469|pubmed:29476059	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26439741|imex:IM-28469-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSRNOG00000016271(gene)|ensembl:ENSRNOT00000023037(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001540"(amyloid-beta binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0010008"(endosome membrane)|go:"GO:0030660"(Golgi-associated vesicle membrane)|go:"GO:0031301"(integral component of organelle membrane)|go:"GO:0042985"(negative regulation of amyloid precursor protein biosynthetic process)|interpro:IPR007084(BRICHOS)|interpro:IPR040145|mint:Q5XIE8|refseq:NP_001006964.1|rgd:620727	rgd:69321|refseq:NP_476534.1|ensembl:ENSRNOG00000010697(gene)|ensembl:ENSRNOT00000014658(transcript)|go:"GO:0003857"(3-hydroxyacyl-CoA dehydrogenase activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0006635"(fatty acid beta-oxidation)|go:"GO:0009725"(response to hormone)|go:"GO:0014823"(response to activity)|go:"GO:0032868"(response to insulin)|go:"GO:0042493"|go:"GO:0042802"(identical protein binding)|go:"GO:0046676"(negative regulation of insulin secretion)|go:"GO:0050796"(regulation of insulin secretion)|go:"GO:0070403"(NAD+ binding)|go:"GO:0120162"(positive regulation of cold-induced thermogenesis)|interpro:IPR006108(3-hydroxyacyl-CoA dehydrogenase, C-terminal)|interpro:IPR006176(3-hydroxyacyl-CoA dehydrogenase, NAD binding)|interpro:IPR006180(3-hydroxyacyl-CoA dehydrogenase, conserved site)|interpro:IPR008927(6-phosphogluconate dehydrogenase, C-terminal-like)|interpro:IPR013328(Dehydrogenase, multihelical)|interpro:IPR022694|interpro:IPR036291|mint:Q9WVK7|reactome:R-RNO-77310|reactome:R-RNO-77346|reactome:R-RNO-77348|reactome:R-RNO-77350|reactome:R-RNO-77352	-	-	-	figure legend:st1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10116(rat-brain-cortex)|taxid:10116(Rattus norvegicus brain cortex)	-	2020/10/30	2020/10/30	rogid:DtE+ZXAZKdCMvUW5K+jXQ5bH07M10116	rogid:dqTvCevVe76aVj0jADypt3XzWa810116	rigid:3wclwrjZRvafcOruQOYnegkn54c	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q5XIE8	uniprotkb:P29147	intact:EBI-15348306|ensembl:ENSRNOP00000023037	intact:EBI-21294686|uniprotkb:Q5U2Q2	psi-mi:itm2b_rat(display_long)|uniprotkb:Itm2b(gene name)|psi-mi:Itm2b(display_short)|uniprotkb:Immature BRI2(gene name synonym)|uniprotkb:Transmembrane protein BRI(gene name synonym)	psi-mi:bdh_rat(display_long)|uniprotkb:Bdh1(gene name)|psi-mi:Bdh1(display_short)|uniprotkb:Bdh(gene name synonym)|uniprotkb:3-hydroxybutyrate dehydrogenase(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Martins et al. (2018)	imex:IM-28469|pubmed:29476059	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26439741|imex:IM-28469-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSRNOG00000016271(gene)|ensembl:ENSRNOT00000023037(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001540"(amyloid-beta binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0010008"(endosome membrane)|go:"GO:0030660"(Golgi-associated vesicle membrane)|go:"GO:0031301"(integral component of organelle membrane)|go:"GO:0042985"(negative regulation of amyloid precursor protein biosynthetic process)|interpro:IPR007084(BRICHOS)|interpro:IPR040145|mint:Q5XIE8|refseq:NP_001006964.1|rgd:620727	mint:P29147|go:"GO:0001889"(liver development)|go:"GO:0003858"(3-hydroxybutyrate dehydrogenase activity)|go:"GO:0005543"(phospholipid binding)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0007420"(brain development)|go:"GO:0007584"(response to nutrient)|go:"GO:0008152"(metabolic process)|go:"GO:0009636"(response to toxic substance)|go:"GO:0009725"(response to hormone)|go:"GO:0032355"(response to estradiol)|go:"GO:0032868"(response to insulin)|go:"GO:0042493"|go:"GO:0042594"(response to starvation)|go:"GO:0045471"(response to ethanol)|go:"GO:0046686"(response to cadmium ion)|go:"GO:0051412"(response to corticosterone)|go:"GO:0060416"(response to growth hormone)|go:"GO:0060612"(adipose tissue development)|go:"GO:0099617"(matrix side of mitochondrial inner membrane)|reactome:R-RNO-77108|reactome:R-RNO-77111|refseq:NP_446447.2|refseq:XP_006248540.1|refseq:XP_008766913.1|interpro:IPR036291|interpro:IPR020904|interpro:IPR002347(Glucose/ribitol dehydrogenase)|rgd:620131	-	-	-	figure legend:st1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10116(rat-brain-cortex)|taxid:10116(Rattus norvegicus brain cortex)	-	2020/10/30	2020/10/30	rogid:DtE+ZXAZKdCMvUW5K+jXQ5bH07M10116	rogid:Vv9XLbzySx2nN+g5Joww7cyDgOM10116	rigid:3wclwrjZRvafcOruQOYnegkn54c	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q5XIE8	uniprotkb:P31647	intact:EBI-15348306|ensembl:ENSRNOP00000023037	intact:EBI-26437303|ensembl:ENSRNOP00000008342	psi-mi:itm2b_rat(display_long)|uniprotkb:Itm2b(gene name)|psi-mi:Itm2b(display_short)|uniprotkb:Immature BRI2(gene name synonym)|uniprotkb:Transmembrane protein BRI(gene name synonym)	psi-mi:s6a11_rat(display_long)|uniprotkb:Slc6a11(gene name)|psi-mi:Slc6a11(display_short)|uniprotkb:Gabt3(gene name synonym)|uniprotkb:Gat-3(gene name synonym)|uniprotkb:Gat-b(gene name synonym)|uniprotkb:Solute carrier family 6 member 11(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Martins et al. (2018)	imex:IM-28469|pubmed:29476059	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26439741|imex:IM-28469-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSRNOG00000016271(gene)|ensembl:ENSRNOT00000023037(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001540"(amyloid-beta binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0010008"(endosome membrane)|go:"GO:0030660"(Golgi-associated vesicle membrane)|go:"GO:0031301"(integral component of organelle membrane)|go:"GO:0042985"(negative regulation of amyloid precursor protein biosynthetic process)|interpro:IPR007084(BRICHOS)|interpro:IPR040145|mint:Q5XIE8|refseq:NP_001006964.1|rgd:620727	ensembl:ENSRNOG00000005697(gene)|ensembl:ENSRNOT00000008342(transcript)|go:"GO:0001504"(neurotransmitter uptake)|go:"GO:0005332"("gamma-aminobutyric acid:sodium symporter activity")|go:"GO:0005737"(cytoplasm)|go:"GO:0099055"(integral component of postsynaptic membrane)|go:"GO:0099056"(integral component of presynaptic membrane)|interpro:IPR000175("Sodium:neurotransmitter symporter")|interpro:IPR002982("Sodium:neurotransmitter symporter, GABA, GAT-3")|interpro:IPR037272|mint:P31647|reactome:R-RNO-442660|reactome:R-RNO-71288|reactome:R-RNO-888593|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006836"(neurotransmitter transport)|go:"GO:0007420"(brain development)|go:"GO:0008028"(monocarboxylic acid transmembrane transporter activity)|go:"GO:0015718"(monocarboxylic acid transport)|go:"GO:0016020"(membrane)|go:"GO:0035725"(sodium ion transmembrane transport)|go:"GO:0042165"(neurotransmitter binding)|go:"GO:0042493"|go:"GO:0042995"(cell projection)|go:"GO:0043005"(neuron projection)|go:"GO:0045202"(synapse)|go:"GO:0098810"(neurotransmitter reuptake)|go:"GO:0098982"(GABA-ergic synapse)|refseq:NP_077348.1|rgd:628737	-	-	-	figure legend:st1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10116(rat-brain-cortex)|taxid:10116(Rattus norvegicus brain cortex)	-	2020/10/30	2020/10/30	rogid:DtE+ZXAZKdCMvUW5K+jXQ5bH07M10116	rogid:9i3Xw3eX7laWYPUzbkNHsaO3kws10116	rigid:3wclwrjZRvafcOruQOYnegkn54c	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q5XIE8	uniprotkb:Q9QX74	intact:EBI-15348306|ensembl:ENSRNOP00000023037	intact:EBI-397902|ensembl:ENSRNOP00000067841|uniprotkb:Q9WUW0|uniprotkb:O70470|uniprotkb:Q6WB19|uniprotkb:Q9QX93|uniprotkb:Q9QZZ9|uniprotkb:Q9WUV9|uniprotkb:Q9WV46	psi-mi:itm2b_rat(display_long)|uniprotkb:Itm2b(gene name)|psi-mi:Itm2b(display_short)|uniprotkb:Immature BRI2(gene name synonym)|uniprotkb:Transmembrane protein BRI(gene name synonym)	psi-mi:shan2_rat(display_long)|uniprotkb:Cortactin-binding protein 1(gene name synonym)|uniprotkb:Proline-rich synapse-associated protein 1(gene name synonym)|uniprotkb:GKAP/SAPAP-interacting protein(gene name synonym)|uniprotkb:SPANK-3(gene name synonym)|uniprotkb:Shank2(gene name)|psi-mi:Shank2(display_short)|uniprotkb:Cortbp1(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Martins et al. (2018)	imex:IM-28469|pubmed:29476059	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26439741|imex:IM-28469-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSRNOG00000016271(gene)|ensembl:ENSRNOT00000023037(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001540"(amyloid-beta binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0010008"(endosome membrane)|go:"GO:0030660"(Golgi-associated vesicle membrane)|go:"GO:0031301"(integral component of organelle membrane)|go:"GO:0042985"(negative regulation of amyloid precursor protein biosynthetic process)|interpro:IPR007084(BRICHOS)|interpro:IPR040145|mint:Q5XIE8|refseq:NP_001006964.1|rgd:620727	rgd:628772|refseq:NP_001004133.1|refseq:NP_597684.1|refseq:NP_597685.1|refseq:NP_958738.1|ensembl:ENSRNOG00000050206(gene)|ensembl:ENSRNOT00000071741(transcript)|go:"GO:0001750"(photoreceptor outer segment)|go:"GO:0001917"(photoreceptor inner segment)|go:"GO:0005883"(neurofilament)|go:"GO:0005886"(plasma membrane)|go:"GO:0007416"(synapse assembly)|go:"GO:0007420"(brain development)|go:"GO:0007584"(response to nutrient)|go:"GO:0007612"(learning)|go:"GO:0007613"(memory)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0008328"(ionotropic glutamate receptor complex)|go:"GO:0014069"(postsynaptic density)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0030160"(synaptic receptor adaptor activity)|go:"GO:0030426"(growth cone)|go:"GO:0030534"(adult behavior)|go:"GO:0031526"(brush border membrane)|go:"GO:0032279"(asymmetric synapse)|go:"GO:0035176"(social behavior)|go:"GO:0035255"(ionotropic glutamate receptor binding)|go:"GO:0035331"(negative regulation of hippo signaling)|go:"GO:0035640"(exploration behavior)|go:"GO:0043005"(neuron projection)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043197"(dendritic spine)|go:"GO:0048786"(presynaptic active zone)|go:"GO:0050807"(regulation of synapse organization)|go:"GO:0051968"(positive regulation of synaptic transmission, glutamatergic)|go:"GO:0060170"(ciliary membrane)|go:"GO:0060291"(long-term synaptic potentiation)|go:"GO:0060292"(long-term synaptic depression)|go:"GO:0071625"(vocalization behavior)|go:"GO:0098686"(hippocampal mossy fiber to CA3 synapse)|go:"GO:0098919"(structural constituent of postsynaptic density)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099562"(maintenance of postsynaptic density structure)|interpro:IPR001452(Src homology-3)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR001660(Sterile alpha motif SAM)|interpro:IPR013761(Sterile alpha motif-type)|interpro:IPR036028|interpro:IPR036034|interpro:IPR041489|mint:Q9QX74|rcsb pdb:6CPJ|reactome:R-RNO-6794361|refseq:XP_017444213.1	-	-	-	figure legend:st1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10116(rat-brain-cortex)|taxid:10116(Rattus norvegicus brain cortex)	-	2020/10/30	2020/10/30	rogid:DtE+ZXAZKdCMvUW5K+jXQ5bH07M10116	rogid:rSjkRiT94GNUbX9ul/buccWjgcM10116	rigid:3wclwrjZRvafcOruQOYnegkn54c	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q5XIE8	uniprotkb:Q9WV48	intact:EBI-15348306|ensembl:ENSRNOP00000023037	intact:EBI-80909|uniprotkb:Q9QZZ8|uniprotkb:Q9WU13|uniprotkb:Q9WUE8|ensembl:ENSRNOP00000026100	psi-mi:itm2b_rat(display_long)|uniprotkb:Itm2b(gene name)|psi-mi:Itm2b(display_short)|uniprotkb:Immature BRI2(gene name synonym)|uniprotkb:Transmembrane protein BRI(gene name synonym)	psi-mi:shan1_rat(display_long)|uniprotkb:Shank1(gene name)|psi-mi:Shank1(display_short)|uniprotkb:GKAP/SAPAP-interacting protein(gene name synonym)|uniprotkb:Synamon(gene name synonym)|uniprotkb:Somatostatin receptor-interacting protein(gene name synonym)|uniprotkb:SPANK-1(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Martins et al. (2018)	imex:IM-28469|pubmed:29476059	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26439741|imex:IM-28469-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSRNOG00000016271(gene)|ensembl:ENSRNOT00000023037(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001540"(amyloid-beta binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0010008"(endosome membrane)|go:"GO:0030660"(Golgi-associated vesicle membrane)|go:"GO:0031301"(integral component of organelle membrane)|go:"GO:0042985"(negative regulation of amyloid precursor protein biosynthetic process)|interpro:IPR007084(BRICHOS)|interpro:IPR040145|mint:Q5XIE8|refseq:NP_001006964.1|rgd:620727	rgd:621011|refseq:NP_113939.2|ensembl:ENSRNOG00000019207(gene)|ensembl:ENSRNOT00000026100(transcript)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0007616"(long-term memory)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008306"(associative learning)|go:"GO:0008328"(ionotropic glutamate receptor complex)|go:"GO:0014069"(postsynaptic density)|go:"GO:0016020"(membrane)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0030159"(signaling receptor complex adaptor activity)|go:"GO:0030160"(synaptic receptor adaptor activity)|go:"GO:0030425"(dendrite)|go:"GO:0030534"(adult behavior)|go:"GO:0032232"(negative regulation of actin filament bundle assembly)|go:"GO:0035176"(social behavior)|go:"GO:0035255"(ionotropic glutamate receptor binding)|go:"GO:0035418"(protein localization to synapse)|go:"GO:0042048"(olfactory behavior)|go:"GO:0042802"(identical protein binding)|go:"GO:0043005"(neuron projection)|go:"GO:0031877"(somatostatin receptor binding)|go:"GO:0043197"(dendritic spine)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045202"(synapse)|go:"GO:0045211"(postsynaptic membrane)|go:"GO:0046959"(habituation)|go:"GO:0050885"(neuromuscular process controlling balance)|go:"GO:0050894"(determination of affect)|go:"GO:0060013"(righting reflex)|go:"GO:0060074"(synapse maturation)|go:"GO:0060076"(excitatory synapse)|go:"GO:0060997"(dendritic spine morphogenesis)|go:"GO:0060999"(positive regulation of dendritic spine development)|go:"GO:0065003"(protein-containing complex assembly)|go:"GO:0071532"(ankyrin repeat binding)|go:"GO:0071625"(vocalization behavior)|go:"GO:0097110"(scaffold protein binding)|go:"GO:0098685"(Schaffer collateral - CA1 synapse)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099173"(postsynapse organization)|go:"GO:2000311"(regulation of AMPA receptor activity)|go:"GO:2000463"(positive regulation of excitatory postsynaptic potential)|interpro:IPR001452(Src homology-3)|interpro:IPR020683|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR036028|interpro:IPR036034|interpro:IPR036770|interpro:IPR041489|mint:Q9WV48|rcsb pdb:1Q3O|rcsb pdb:1Q3P|rcsb pdb:3L4F|rcsb pdb:3QJM|interpro:IPR001660(Sterile alpha motif SAM)|rcsb pdb:3QJN|rcsb pdb:7A9B|interpro:IPR002110(Ankyrin)|reactome:R-RNO-6794361|interpro:IPR013761(Sterile alpha motif-type)|refseq:XP_017445247.1|refseq:XP_017445248.1|refseq:XP_017445249.1|refseq:XP_017445250.1	-	-	-	figure legend:st1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10116(rat-brain-cortex)|taxid:10116(Rattus norvegicus brain cortex)	-	2020/10/30	2020/10/30	rogid:DtE+ZXAZKdCMvUW5K+jXQ5bH07M10116	rogid:EHavC08yPAiG9wbnxLHyWaRZj4g10116	rigid:3wclwrjZRvafcOruQOYnegkn54c	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q5XIE8	uniprotkb:Q64578	intact:EBI-15348306|ensembl:ENSRNOP00000023037	intact:EBI-26437245	psi-mi:itm2b_rat(display_long)|uniprotkb:Itm2b(gene name)|psi-mi:Itm2b(display_short)|uniprotkb:Immature BRI2(gene name synonym)|uniprotkb:Transmembrane protein BRI(gene name synonym)	psi-mi:at2a1_rat(display_long)|uniprotkb:Atp2a1(gene name)|psi-mi:Atp2a1(display_short)|uniprotkb:Calcium pump 1(gene name synonym)|uniprotkb:Calcium-transporting ATPase sarcoplasmic reticulum type, fast twitch skeletal muscle isoform(gene name synonym)|uniprotkb:"Endoplasmic reticulum class 1/2 Ca(2+) ATPase"(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Martins et al. (2018)	imex:IM-28469|pubmed:29476059	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26439741|imex:IM-28469-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSRNOG00000016271(gene)|ensembl:ENSRNOT00000023037(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001540"(amyloid-beta binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0010008"(endosome membrane)|go:"GO:0030660"(Golgi-associated vesicle membrane)|go:"GO:0031301"(integral component of organelle membrane)|go:"GO:0042985"(negative regulation of amyloid precursor protein biosynthetic process)|interpro:IPR007084(BRICHOS)|interpro:IPR040145|mint:Q5XIE8|refseq:NP_001006964.1|rgd:620727	go:"GO:0005338"(nucleotide-sugar transmembrane transporter activity)|go:"GO:0005388"(P-type calcium transporter activity)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005739"(mitochondrion)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005793"(endoplasmic reticulum-Golgi intermediate compartment)|go:"GO:0006816"(calcium ion transport)|go:"GO:0006874"(cellular calcium ion homeostasis)|go:"GO:0006937"(regulation of muscle contraction)|go:"GO:0006942"(regulation of striated muscle contraction)|go:"GO:0008553"(P-type proton-exporting transporter activity)|go:"GO:0008637"(apoptotic mitochondrial changes)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016529"(sarcoplasmic reticulum)|go:"GO:0030899"(calcium-dependent ATPase activity)|go:"GO:0031448"(positive regulation of fast-twitch skeletal muscle fiber contraction)|go:"GO:0031673"(H zone)|go:"GO:0031674"(I band)|go:"GO:0032470"(positive regulation of endoplasmic reticulum calcium ion concentration)|go:"GO:0032471"(negative regulation of endoplasmic reticulum calcium ion concentration)|go:"GO:0034976"(response to endoplasmic reticulum stress)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0043434"(response to peptide hormone)|go:"GO:0045988"(negative regulation of striated muscle contraction)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051561"(positive regulation of mitochondrial calcium ion concentration)|go:"GO:0051659"(maintenance of mitochondrion location)|go:"GO:0070059"(intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress)|go:"GO:0070296"(sarcoplasmic reticulum calcium ion transport)|go:"GO:0070509"(calcium ion import)|go:"GO:0070588"(calcium ion transmembrane transport)|go:"GO:0090076"(relaxation of skeletal muscle)|go:"GO:0106134"(positive regulation of cardiac muscle cell contraction)|go:"GO:1901896"(positive regulation of ATPase-coupled calcium transmembrane transporter activity)|go:"GO:1902082"(positive regulation of calcium ion import into sarcoplasmic reticulum)|go:"GO:1990036"(calcium ion import into sarcoplasmic reticulum)|go:"GO:0033017"(sarcoplasmic reticulum membrane)|mint:Q64578|refseq:NP_478120.1|interpro:IPR006068(ATPase, P-type cation-transporter, C-terminal)|interpro:IPR004014(ATPase, P-type cation-transporter, N-terminal)|interpro:IPR023299|interpro:IPR018303|interpro:IPR023298|interpro:IPR008250(E1-E2 ATPase-associated region)|interpro:IPR036412|interpro:IPR023214|interpro:IPR005782(Calcium ATPase)|interpro:IPR001757(ATPase, P-type, K/Mg/Cd/Cu/Zn/Na/Ca/Na/H-transporter)|rgd:621293|interpro:IPR044492	-	-	-	figure legend:st1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10116(rat-brain-cortex)|taxid:10116(Rattus norvegicus brain cortex)	-	2020/10/30	2020/10/30	rogid:DtE+ZXAZKdCMvUW5K+jXQ5bH07M10116	rogid:QeoX1KkHMSA+GNGUBG0IGxUfDyM10116	rigid:3wclwrjZRvafcOruQOYnegkn54c	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q5XIE8	uniprotkb:P26284	intact:EBI-15348306|ensembl:ENSRNOP00000023037	intact:EBI-1163773	psi-mi:itm2b_rat(display_long)|uniprotkb:Itm2b(gene name)|psi-mi:Itm2b(display_short)|uniprotkb:Immature BRI2(gene name synonym)|uniprotkb:Transmembrane protein BRI(gene name synonym)	psi-mi:odpa_rat(display_long)|uniprotkb:PDHE1-A type I(gene name synonym)|uniprotkb:Pdha1(gene name)|psi-mi:Pdha1(display_short)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Martins et al. (2018)	imex:IM-28469|pubmed:29476059	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26439741|imex:IM-28469-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSRNOG00000016271(gene)|ensembl:ENSRNOT00000023037(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001540"(amyloid-beta binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0010008"(endosome membrane)|go:"GO:0030660"(Golgi-associated vesicle membrane)|go:"GO:0031301"(integral component of organelle membrane)|go:"GO:0042985"(negative regulation of amyloid precursor protein biosynthetic process)|interpro:IPR007084(BRICHOS)|interpro:IPR040145|mint:Q5XIE8|refseq:NP_001006964.1|rgd:620727	interpro:IPR001017(Dehydrogenase, E1 component)|interpro:IPR017597("Pyruvate dehydrogenase (acetyl-transferring) E1 component, alpha subunit, subgroup y")|rgd:3286|go:"GO:0006006"(glucose metabolic process)|go:"GO:0006086"(acetyl-CoA biosynthetic process from pyruvate)|go:"GO:0006099"(tricarboxylic acid cycle)|go:"GO:0034604"("pyruvate dehydrogenase (NAD+) activity")|go:"GO:0045254"(pyruvate dehydrogenase complex)|go:"GO:0061732"(mitochondrial acetyl-CoA biosynthetic process from pyruvate)|reactome:R-RNO-204174|reactome:R-RNO-389661|reactome:R-RNO-5362517|reactome:R-RNO-70268|go:"GO:0004738"(pyruvate dehydrogenase activity)|go:"GO:0004739"("pyruvate dehydrogenase (acetyl-transferring) activity")|go:"GO:0005739"(mitochondrion)|go:"GO:0005967"(mitochondrial pyruvate dehydrogenase complex)|interpro:IPR029061|mint:P26284	-	-	-	figure legend:st1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10116(rat-brain-cortex)|taxid:10116(Rattus norvegicus brain cortex)	-	2020/10/30	2020/10/30	rogid:DtE+ZXAZKdCMvUW5K+jXQ5bH07M10116	rogid:ZS2XIIvPJLzbaoUBw21HHJw6gcw10116	rigid:3wclwrjZRvafcOruQOYnegkn54c	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q5XIE8	uniprotkb:A7VJC2	intact:EBI-15348306|ensembl:ENSRNOP00000023037	intact:EBI-16220125|uniprotkb:A7VJC1|uniprotkb:A7VJC3|uniprotkb:A7VJC4	psi-mi:itm2b_rat(display_long)|uniprotkb:Itm2b(gene name)|psi-mi:Itm2b(display_short)|uniprotkb:Immature BRI2(gene name synonym)|uniprotkb:Transmembrane protein BRI(gene name synonym)	psi-mi:roa2_rat(display_long)|uniprotkb:Hnrnpa2b1(gene name)|psi-mi:Hnrnpa2b1(display_short)|uniprotkb:Hnrnp(gene name synonym)|uniprotkb:Hnrpa2b1(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Martins et al. (2018)	imex:IM-28469|pubmed:29476059	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26439741|imex:IM-28469-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSRNOG00000016271(gene)|ensembl:ENSRNOT00000023037(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001540"(amyloid-beta binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0010008"(endosome membrane)|go:"GO:0030660"(Golgi-associated vesicle membrane)|go:"GO:0031301"(integral component of organelle membrane)|go:"GO:0042985"(negative regulation of amyloid precursor protein biosynthetic process)|interpro:IPR007084(BRICHOS)|interpro:IPR040145|mint:Q5XIE8|refseq:NP_001006964.1|rgd:620727	go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0000785"(chromatin)|go:"GO:0001069"(regulatory region RNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0003730"(mRNA 3'-UTR binding)|go:"GO:0005634"(nucleus)|go:"GO:0005681"(spliceosomal complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0006397"(mRNA processing)|go:"GO:0006406"(mRNA export from nucleus)|go:"GO:0008584"(male gonad development)|go:"GO:0015030"(Cajal body)|go:"GO:0016233"(telomere capping)|go:"GO:0016363"(nuclear matrix)|go:"GO:0030324"(lung development)|go:"GO:0031053"(primary miRNA processing)|go:"GO:0035198"(miRNA binding)|go:"GO:0043005"(neuron projection)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043047"(single-stranded telomeric DNA binding)|go:"GO:0043204"(perikaryon)|go:"GO:0044806"(G-quadruplex DNA unwinding)|go:"GO:0048025"(negative regulation of mRNA splicing, via spliceosome)|go:"GO:0048709"(oligodendrocyte differentiation)|go:"GO:0050658"(RNA transport)|go:"GO:0051385"(response to mineralocorticoid)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070182"(DNA polymerase binding)|go:"GO:0071013"(catalytic step 2 spliceosome)|go:"GO:0071598"(neuronal ribonucleoprotein granule)|go:"GO:0097157"(pre-mRNA intronic binding)|go:"GO:0098505"(G-rich strand telomeric DNA binding)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099524"(postsynaptic cytosol)|go:"GO:1904358"(positive regulation of telomere maintenance via telomere lengthening)|go:"GO:1905663"(positive regulation of telomerase RNA reverse transcriptase activity)|go:"GO:1990247"(N6-methyladenosine-containing RNA binding)|go:"GO:1990428"(miRNA transport)|go:"GO:1990715"(mRNA CDS binding)|go:"GO:1990904"(ribonucleoprotein complex)|reactome:R-RNO-72163|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|mint:A7VJC2|rgd:1310403|refseq:NP_001098083.1|interpro:IPR034489|interpro:IPR034486|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR035979	-	-	-	figure legend:st1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10116(rat-brain-cortex)|taxid:10116(Rattus norvegicus brain cortex)	-	2020/10/30	2020/10/30	rogid:DtE+ZXAZKdCMvUW5K+jXQ5bH07M10116	rogid:RZtl5bMFuLp7kleC3+GUF5SQmEI10116	rigid:3wclwrjZRvafcOruQOYnegkn54c	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q5XIE8	uniprotkb:P54290	intact:EBI-15348306|ensembl:ENSRNOP00000023037	intact:EBI-2466294	psi-mi:itm2b_rat(display_long)|uniprotkb:Itm2b(gene name)|psi-mi:Itm2b(display_short)|uniprotkb:Immature BRI2(gene name synonym)|uniprotkb:Transmembrane protein BRI(gene name synonym)	psi-mi:ca2d1_rat(display_long)|uniprotkb:Cacna2d1(gene name)|psi-mi:Cacna2d1(display_short)|uniprotkb:Cacnl2a(gene name synonym)|uniprotkb:Cchl2a(gene name synonym)|uniprotkb:Voltage-gated calcium channel subunit alpha-2/delta-1(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Martins et al. (2018)	imex:IM-28469|pubmed:29476059	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26439741|imex:IM-28469-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSRNOG00000016271(gene)|ensembl:ENSRNOT00000023037(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001540"(amyloid-beta binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0010008"(endosome membrane)|go:"GO:0030660"(Golgi-associated vesicle membrane)|go:"GO:0031301"(integral component of organelle membrane)|go:"GO:0042985"(negative regulation of amyloid precursor protein biosynthetic process)|interpro:IPR007084(BRICHOS)|interpro:IPR040145|mint:Q5XIE8|refseq:NP_001006964.1|rgd:620727	go:"GO:0005245"(voltage-gated calcium channel activity)|go:"GO:0005891"(voltage-gated calcium channel complex)|go:"GO:0006816"(calcium ion transport)|go:"GO:0016529"(sarcoplasmic reticulum)|go:"GO:0030315"(T-tubule)|go:"GO:0046872"(metal ion binding)|go:"GO:0051924"(regulation of calcium ion transport)|go:"GO:0060307"(regulation of ventricular cardiac muscle cell membrane repolarization)|go:"GO:0060402"(calcium ion transport into cytosol)|go:"GO:0061577"(calcium ion transmembrane transport via high voltage-gated calcium channel)|go:"GO:0070588"(calcium ion transmembrane transport)|go:"GO:0086002"(cardiac muscle cell action potential involved in contraction)|go:"GO:0086048"(membrane depolarization during bundle of His cell action potential)|go:"GO:0086091"(regulation of heart rate by cardiac conduction)|go:"GO:0098903"(regulation of membrane repolarization during action potential)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099025"(anchored component of postsynaptic membrane)|go:"GO:0099029"(anchored component of presynaptic active zone membrane)|go:"GO:1901387"(positive regulation of voltage-gated calcium channel activity)|go:"GO:1901843"(positive regulation of high voltage-gated calcium channel activity)|go:"GO:1902514"(regulation of calcium ion transmembrane transport via high voltage-gated calcium channel)|go:"GO:1904646"(cellular response to amyloid-beta)|go:"GO:1990454"(L-type voltage-gated calcium channel complex)|interpro:IPR013680(Voltage-dependent calcium channel, alpha-2/delta subunit, conserved region)|interpro:IPR013608(VWA N-terminal)|interpro:IPR002035(von Willebrand factor, type A)|rgd:2247|interpro:IPR036465|mint:P54290	-	-	-	figure legend:st1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10116(rat-brain-cortex)|taxid:10116(Rattus norvegicus brain cortex)	-	2020/10/30	2020/10/30	rogid:DtE+ZXAZKdCMvUW5K+jXQ5bH07M10116	rogid:S7R5HLesr6V4Ugx1jVxYk2tE/8M10116	rigid:3wclwrjZRvafcOruQOYnegkn54c	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q5XIE8	uniprotkb:Q9JLU4	intact:EBI-15348306|ensembl:ENSRNOP00000023037	intact:EBI-6271152|uniprotkb:Q9WUY7|uniprotkb:Q9WV47	psi-mi:itm2b_rat(display_long)|uniprotkb:Itm2b(gene name)|psi-mi:Itm2b(display_short)|uniprotkb:Immature BRI2(gene name synonym)|uniprotkb:Transmembrane protein BRI(gene name synonym)	psi-mi:shan3_rat(display_long)|uniprotkb:Shank3(gene name)|psi-mi:Shank3(display_short)|uniprotkb:Proline-rich synapse-associated protein 2(gene name synonym)|uniprotkb:SPANK-2(gene name synonym)|uniprotkb:Prosap2(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Martins et al. (2018)	imex:IM-28469|pubmed:29476059	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26439741|imex:IM-28469-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSRNOG00000016271(gene)|ensembl:ENSRNOT00000023037(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001540"(amyloid-beta binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0010008"(endosome membrane)|go:"GO:0030660"(Golgi-associated vesicle membrane)|go:"GO:0031301"(integral component of organelle membrane)|go:"GO:0042985"(negative regulation of amyloid precursor protein biosynthetic process)|interpro:IPR007084(BRICHOS)|interpro:IPR040145|mint:Q5XIE8|refseq:NP_001006964.1|rgd:620727	go:"GO:0000165"(MAPK cascade)|go:"GO:0001838"(embryonic epithelial tube formation)|go:"GO:0003779"(actin binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0007416"(synapse assembly)|go:"GO:0007611"(learning or memory)|go:"GO:0007612"(learning)|go:"GO:0007613"(memory)|go:"GO:0007626"(locomotory behavior)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008270"(zinc ion binding)|go:"GO:0014069"(postsynaptic density)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0021773"(striatal medium spiny neuron differentiation)|go:"GO:0030160"(synaptic receptor adaptor activity)|go:"GO:0030534"(adult behavior)|go:"GO:0031234"(extrinsic component of cytoplasmic side of plasma membrane)|go:"GO:0032232"(negative regulation of actin filament bundle assembly)|go:"GO:0035176"(social behavior)|go:"GO:0035255"(ionotropic glutamate receptor binding)|go:"GO:0035640"(exploration behavior)|go:"GO:0035641"(locomotory exploration behavior)|go:"GO:0040011"(locomotion)|go:"GO:0042297"(vocal learning)|go:"GO:0042802"(identical protein binding)|go:"GO:0043005"(neuron projection)|go:"GO:0043197"(dendritic spine)|go:"GO:0043621"(protein self-association)|go:"GO:0044309"(neuron spine)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045202"(synapse)|go:"GO:0045794"(negative regulation of cell volume)|go:"GO:0048167"(regulation of synaptic plasticity)|go:"GO:0048170"(positive regulation of long-term neuronal synaptic plasticity)|go:"GO:0048854"(brain morphogenesis)|go:"GO:0050807"(regulation of synapse organization)|go:"GO:0050885"(neuromuscular process controlling balance)|go:"GO:0051835"(positive regulation of synapse structural plasticity)|go:"GO:0051968"(positive regulation of synaptic transmission, glutamatergic)|go:"GO:0060170"(ciliary membrane)|go:"GO:0060291"(long-term synaptic potentiation)|go:"GO:0060292"(long-term synaptic depression)|go:"GO:0060997"(dendritic spine morphogenesis)|go:"GO:0060999"(positive regulation of dendritic spine development)|go:"GO:0061001"(regulation of dendritic spine morphogenesis)|go:"GO:0071625"(vocalization behavior)|go:"GO:0097107"(postsynaptic density assembly)|go:"GO:0097110"(scaffold protein binding)|go:"GO:0097113"(AMPA glutamate receptor clustering)|go:"GO:0097114"(NMDA glutamate receptor clustering)|go:"GO:0097117"(guanylate kinase-associated protein clustering)|go:"GO:0098919"(structural constituent of postsynaptic density)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099092"(postsynaptic density, intracellular component)|go:"GO:0099562"(maintenance of postsynaptic density structure)|go:"GO:1900271"(regulation of long-term synaptic potentiation)|go:"GO:1900273"(positive regulation of long-term synaptic potentiation)|go:"GO:1900451"(positive regulation of glutamate receptor signaling pathway)|go:"GO:1900452"(regulation of long-term synaptic depression)|go:"GO:1904717"(regulation of AMPA glutamate receptor clustering)|go:"GO:2000463"(positive regulation of excitatory postsynaptic potential)|go:"GO:2000821"(regulation of grooming behavior)|go:"GO:2000822"(regulation of behavioral fear response)|go:"GO:2000969"(positive regulation of AMPA receptor activity)|rcsb pdb:2F3N|rcsb pdb:2F44|rcsb pdb:5G4X|rcsb pdb:5O99|rcsb pdb:5OVA|rcsb pdb:5OVC|rcsb pdb:5OVP|rcsb pdb:5OVV|rcsb pdb:6EXJ|reactome:R-RNO-6794361|reactome:R-RNO-8853659|mint:Q9JLU4|rgd:69264|refseq:NP_067708.1|interpro:IPR002110(Ankyrin)|interpro:IPR020683|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR001660(Sterile alpha motif SAM)|interpro:IPR013761(Sterile alpha motif-type)|interpro:IPR001452(Src homology-3)|interpro:IPR036028|interpro:IPR036034|interpro:IPR036770|interpro:IPR041489	-	-	-	figure legend:st1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10116(rat-brain-cortex)|taxid:10116(Rattus norvegicus brain cortex)	-	2020/10/30	2020/10/30	rogid:DtE+ZXAZKdCMvUW5K+jXQ5bH07M10116	rogid:5f5+bUHHbxnta5KzhCtIoW/+MWk10116	rigid:3wclwrjZRvafcOruQOYnegkn54c	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q5XIE8	uniprotkb:Q562B5	intact:EBI-15348306|ensembl:ENSRNOP00000023037	intact:EBI-26439416	psi-mi:itm2b_rat(display_long)|uniprotkb:Itm2b(gene name)|psi-mi:Itm2b(display_short)|uniprotkb:Immature BRI2(gene name synonym)|uniprotkb:Transmembrane protein BRI(gene name synonym)	psi-mi:pgam5_rat(display_long)|uniprotkb:Pgam5(gene name)|psi-mi:Pgam5(display_short)|uniprotkb:Phosphoglycerate mutase family member 5(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Martins et al. (2018)	imex:IM-28469|pubmed:29476059	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26439741|imex:IM-28469-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSRNOG00000016271(gene)|ensembl:ENSRNOT00000023037(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001540"(amyloid-beta binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0010008"(endosome membrane)|go:"GO:0030660"(Golgi-associated vesicle membrane)|go:"GO:0031301"(integral component of organelle membrane)|go:"GO:0042985"(negative regulation of amyloid precursor protein biosynthetic process)|interpro:IPR007084(BRICHOS)|interpro:IPR040145|mint:Q5XIE8|refseq:NP_001006964.1|rgd:620727	go:"GO:0070266"(necroptotic process)|go:"GO:0106306"|go:"GO:0106307"|go:"GO:0120163"(negative regulation of cold-induced thermogenesis)|reactome:R-RNO-8934903|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0004722"(protein serine/threonine phosphatase activity)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016311"(dephosphorylation)|go:"GO:0016791"(phosphatase activity)|mint:Q562B5|refseq:NP_001020443.1|interpro:IPR013078(Phosphoglycerate mutase)|interpro:IPR029033|rgd:1312028	-	-	-	figure legend:st1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10116(rat-brain-cortex)|taxid:10116(Rattus norvegicus brain cortex)	-	2020/10/30	2020/10/30	rogid:DtE+ZXAZKdCMvUW5K+jXQ5bH07M10116	rogid:aW9wPvmbtWxmg6uSJ1sh7CTkyA010116	rigid:3wclwrjZRvafcOruQOYnegkn54c	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q5XIE8	uniprotkb:Q64620	intact:EBI-15348306|ensembl:ENSRNOP00000023037	intact:EBI-1187315|uniprotkb:Q6AZ47|ensembl:ENSRNOP00000021176	psi-mi:itm2b_rat(display_long)|uniprotkb:Itm2b(gene name)|psi-mi:Itm2b(display_short)|uniprotkb:Immature BRI2(gene name synonym)|uniprotkb:Transmembrane protein BRI(gene name synonym)	psi-mi:ppp6_rat(display_long)|uniprotkb:Protein phosphatase V(gene name synonym)|uniprotkb:Ppp6c(gene name)|psi-mi:Ppp6c(display_short)|uniprotkb:Ppv(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Martins et al. (2018)	imex:IM-28469|pubmed:29476059	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26439741|imex:IM-28469-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSRNOG00000016271(gene)|ensembl:ENSRNOT00000023037(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001540"(amyloid-beta binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0010008"(endosome membrane)|go:"GO:0030660"(Golgi-associated vesicle membrane)|go:"GO:0031301"(integral component of organelle membrane)|go:"GO:0042985"(negative regulation of amyloid precursor protein biosynthetic process)|interpro:IPR007084(BRICHOS)|interpro:IPR040145|mint:Q5XIE8|refseq:NP_001006964.1|rgd:620727	rgd:708460|refseq:NP_598273.2|ensembl:ENSRNOG00000015145(gene)|ensembl:ENSRNOT00000021176(transcript)|go:"GO:0004722"(protein serine/threonine phosphatase activity)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0006470"(protein dephosphorylation)|go:"GO:0007049"(cell cycle)|go:"GO:0045087"(innate immune response)|go:"GO:0046872"(metal ion binding)|go:"GO:0106306"|go:"GO:0106307"|interpro:IPR004843(Metallophosphoesterase)|interpro:IPR006186("Serine/threonine-specific protein phosphatase and bis(5-nucleosyl)-tetraphosphatase")|interpro:IPR029052|mint:Q64620|reactome:R-RNO-171319|reactome:R-RNO-204005	-	-	-	figure legend:st1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10116(rat-brain-cortex)|taxid:10116(Rattus norvegicus brain cortex)	-	2020/10/30	2020/10/30	rogid:DtE+ZXAZKdCMvUW5K+jXQ5bH07M10116	rogid:R0jsZoqJLoRaSNMNCLRkQ40CC+o10116	rigid:3wclwrjZRvafcOruQOYnegkn54c	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q5XIE8	uniprotkb:Q9JKE3	intact:EBI-15348306|ensembl:ENSRNOP00000023037	intact:EBI-26439394	psi-mi:itm2b_rat(display_long)|uniprotkb:Itm2b(gene name)|psi-mi:Itm2b(display_short)|uniprotkb:Immature BRI2(gene name synonym)|uniprotkb:Transmembrane protein BRI(gene name synonym)	psi-mi:scam5_rat(display_long)|uniprotkb:Scamp5(gene name)|psi-mi:Scamp5(display_short)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Martins et al. (2018)	imex:IM-28469|pubmed:29476059	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26439741|imex:IM-28469-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSRNOG00000016271(gene)|ensembl:ENSRNOT00000023037(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001540"(amyloid-beta binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0010008"(endosome membrane)|go:"GO:0030660"(Golgi-associated vesicle membrane)|go:"GO:0031301"(integral component of organelle membrane)|go:"GO:0042985"(negative regulation of amyloid precursor protein biosynthetic process)|interpro:IPR007084(BRICHOS)|interpro:IPR040145|mint:Q5XIE8|refseq:NP_001006964.1|rgd:620727	go:"GO:0000139"(Golgi membrane)|go:"GO:0001819"(positive regulation of cytokine production)|go:"GO:0005886"(plasma membrane)|go:"GO:0006887"(exocytosis)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0015031"(protein transport)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030285"(integral component of synaptic vesicle membrane)|go:"GO:0032588"(trans-Golgi network membrane)|go:"GO:0034976"(response to endoplasmic reticulum stress)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045806"(negative regulation of endocytosis)|go:"GO:0045956"(positive regulation of calcium ion-dependent exocytosis)|go:"GO:0055038"(recycling endosome membrane)|go:"GO:1900242"(regulation of synaptic vesicle endocytosis)|mint:Q9JKE3|refseq:NP_113914.1|interpro:IPR007273(SCAMP)|rgd:68356	-	-	-	figure legend:st1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10116(rat-brain-cortex)|taxid:10116(Rattus norvegicus brain cortex)	-	2020/10/30	2020/10/30	rogid:DtE+ZXAZKdCMvUW5K+jXQ5bH07M10116	rogid:soL6q8WquSODQzA7PNvfMc5imXU10116	rigid:3wclwrjZRvafcOruQOYnegkn54c	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q5XIE8	uniprotkb:P56603	intact:EBI-15348306|ensembl:ENSRNOP00000023037	intact:EBI-21233831	psi-mi:itm2b_rat(display_long)|uniprotkb:Itm2b(gene name)|psi-mi:Itm2b(display_short)|uniprotkb:Immature BRI2(gene name synonym)|uniprotkb:Transmembrane protein BRI(gene name synonym)	psi-mi:scam1_rat(display_long)|uniprotkb:Scamp1(gene name)|psi-mi:Scamp1(display_short)|uniprotkb:Scamp(gene name synonym)|uniprotkb:SCAMP 37(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Martins et al. (2018)	imex:IM-28469|pubmed:29476059	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26439741|imex:IM-28469-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSRNOG00000016271(gene)|ensembl:ENSRNOT00000023037(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001540"(amyloid-beta binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0010008"(endosome membrane)|go:"GO:0030660"(Golgi-associated vesicle membrane)|go:"GO:0031301"(integral component of organelle membrane)|go:"GO:0042985"(negative regulation of amyloid precursor protein biosynthetic process)|interpro:IPR007084(BRICHOS)|interpro:IPR040145|mint:Q5XIE8|refseq:NP_001006964.1|rgd:620727	go:"GO:0005802"(trans-Golgi network)|go:"GO:0006887"(exocytosis)|go:"GO:0006897"(endocytosis)|go:"GO:0015031"(protein transport)|go:"GO:0016021"(integral component of membrane)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030136"(clathrin-coated vesicle)|go:"GO:0030285"(integral component of synaptic vesicle membrane)|go:"GO:0030659"(cytoplasmic vesicle membrane)|go:"GO:0030672"(synaptic vesicle membrane)|go:"GO:0032588"(trans-Golgi network membrane)|go:"GO:0042589"(zymogen granule membrane)|go:"GO:0043195"(terminal bouton)|go:"GO:0045202"(synapse)|go:"GO:0055038"(recycling endosome membrane)|reactome:R-RNO-6798695|rgd:3625|refseq:NP_001094106.1|interpro:IPR007273(SCAMP)|mint:P56603	-	-	-	figure legend:st1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10116(rat-brain-cortex)|taxid:10116(Rattus norvegicus brain cortex)	-	2020/10/30	2020/10/30	rogid:DtE+ZXAZKdCMvUW5K+jXQ5bH07M10116	rogid:Z/+el7KYf548bEanWLdw9YQENmY10116	rigid:3wclwrjZRvafcOruQOYnegkn54c	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q5XIE8	uniprotkb:P63245	intact:EBI-15348306|ensembl:ENSRNOP00000023037	intact:EBI-296759|ensembl:ENSRNOP00000068758|ensembl:ENSRNOP00000074147|uniprotkb:P25388|uniprotkb:P99049	psi-mi:itm2b_rat(display_long)|uniprotkb:Itm2b(gene name)|psi-mi:Itm2b(display_short)|uniprotkb:Immature BRI2(gene name synonym)|uniprotkb:Transmembrane protein BRI(gene name synonym)	psi-mi:rack1_rat(display_long)|uniprotkb:Guanine nucleotide-binding protein subunit beta-2-like 1(gene name synonym)|uniprotkb:Receptor for activated C kinase(gene name synonym)|uniprotkb:Receptor of activated protein kinase C 1(gene name synonym)|uniprotkb:Rack1(gene name)|psi-mi:Rack1(display_short)|uniprotkb:Gnb2l1(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Martins et al. (2018)	imex:IM-28469|pubmed:29476059	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26439741|imex:IM-28469-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSRNOG00000016271(gene)|ensembl:ENSRNOT00000023037(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001540"(amyloid-beta binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0010008"(endosome membrane)|go:"GO:0030660"(Golgi-associated vesicle membrane)|go:"GO:0031301"(integral component of organelle membrane)|go:"GO:0042985"(negative regulation of amyloid precursor protein biosynthetic process)|interpro:IPR007084(BRICHOS)|interpro:IPR040145|mint:Q5XIE8|refseq:NP_001006964.1|rgd:620727	go:"GO:0015935"(small ribosomal subunit)|go:"GO:0016020"(membrane)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0017148"(negative regulation of translation)|go:"GO:0019899"(enzyme binding)|go:"GO:0019903"(protein phosphatase binding)|go:"GO:0030178"(negative regulation of Wnt signaling pathway)|go:"GO:0030292"(protein tyrosine kinase inhibitor activity)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0030332"(cyclin binding)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0030425"(dendrite)|go:"GO:0030496"(midbody)|go:"GO:0030971"(receptor tyrosine kinase binding)|go:"GO:0031334"(positive regulation of protein-containing complex assembly)|go:"GO:0032091"(negative regulation of protein binding)|go:"GO:0032436"(positive regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0032880"(regulation of protein localization)|ensembl:ENSRNOG00000049070(gene)|ensembl:ENSRNOT00000072179(transcript)|ensembl:ENSRNOT00000084232(transcript)|go:"GO:0001649"(osteoblast differentiation)|go:"GO:0001891"(phagocytic cup)|go:"GO:0001934"(positive regulation of protein phosphorylation)|go:"GO:0005080"(protein kinase C binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0006412"(translation)|go:"GO:0006919"(activation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0007049"(cell cycle)|go:"GO:0007205"(protein kinase C-activating G protein-coupled receptor signaling pathway)|go:"GO:0007369"(gastrulation)|go:"GO:0008200"(ion channel inhibitor activity)|go:"GO:0008656"(cysteine-type endopeptidase activator activity involved in apoptotic process)|go:"GO:0010629"(negative regulation of gene expression)|ensembl:ENSRNOG00000052620(gene)|go:"GO:0035591"(signaling adaptor activity)|go:"GO:0042169"(SH2 domain binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0042998"(positive regulation of Golgi to plasma membrane protein transport)|go:"GO:0043005"(neuron projection)|go:"GO:0043022"(ribosome binding)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043204"(perikaryon)|go:"GO:0043473"(pigmentation)|go:"GO:0043547"(positive regulation of GTPase activity)|go:"GO:0044297"(cell body)|go:"GO:0045879"(negative regulation of smoothened signaling pathway)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0048511"(rhythmic process)|go:"GO:0050765"(negative regulation of phagocytosis)|go:"GO:0051302"(regulation of cell division)|go:"GO:0051343"(positive regulation of cyclic-nucleotide phosphodiesterase activity)|go:"GO:0033137"(negative regulation of peptidyl-serine phosphorylation)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0051898"(negative regulation of protein kinase B signaling)|go:"GO:0051901"(positive regulation of mitochondrial depolarization)|go:"GO:0071333"(cellular response to glucose stimulus)|go:"GO:0071363"(cellular response to growth factor stimulus)|go:"GO:0072344"(rescue of stalled ribosome)|go:"GO:1903076"(regulation of protein localization to plasma membrane)|go:"GO:1903208"(negative regulation of hydrogen peroxide-induced neuron death)|go:"GO:1990630"(IRE1-RACK1-PP2A complex)|go:"GO:2000114"(regulation of establishment of cell polarity)|go:"GO:2000543"(positive regulation of gastrulation)|go:"GO:2001244"(positive regulation of intrinsic apoptotic signaling pathway)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019775|interpro:IPR020472|interpro:IPR036322|go:"GO:0051434"(BH3 domain binding)|mint:P63245|reactome:R-RNO-5357905|reactome:R-RNO-5357956|reactome:R-RNO-5626978|rgd:69229|refseq:NP_570090.2	-	-	-	figure legend:st1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10116(rat-brain-cortex)|taxid:10116(Rattus norvegicus brain cortex)	-	2020/10/30	2020/10/30	rogid:DtE+ZXAZKdCMvUW5K+jXQ5bH07M10116	rogid:LXHlhPtxUzHJNncoPteGw2iXsFg10116	rigid:3wclwrjZRvafcOruQOYnegkn54c	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q5XIE8	uniprotkb:P10499	intact:EBI-15348306|ensembl:ENSRNOP00000023037	intact:EBI-631463|ensembl:ENSRNOP00000026731	psi-mi:itm2b_rat(display_long)|uniprotkb:Itm2b(gene name)|psi-mi:Itm2b(display_short)|uniprotkb:Immature BRI2(gene name synonym)|uniprotkb:Transmembrane protein BRI(gene name synonym)	psi-mi:kcna1_rat(display_long)|uniprotkb:Voltage-gated potassium channel subunit Kv1.1(gene name synonym)|uniprotkb:RBKI(gene name synonym)|uniprotkb:RCK1(gene name synonym)|uniprotkb:Kcna1(gene name)|psi-mi:Kcna1(display_short)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Martins et al. (2018)	imex:IM-28469|pubmed:29476059	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26439741|imex:IM-28469-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSRNOG00000016271(gene)|ensembl:ENSRNOT00000023037(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001540"(amyloid-beta binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0010008"(endosome membrane)|go:"GO:0030660"(Golgi-associated vesicle membrane)|go:"GO:0031301"(integral component of organelle membrane)|go:"GO:0042985"(negative regulation of amyloid precursor protein biosynthetic process)|interpro:IPR007084(BRICHOS)|interpro:IPR040145|mint:Q5XIE8|refseq:NP_001006964.1|rgd:620727	rgd:2949|refseq:NP_775118.1|go:"GO:0019228"(neuronal action potential)|go:"GO:0021766"(hippocampus development)|go:"GO:0023041"(neuronal signal transduction)|go:"GO:0030054"(cell junction)|go:"GO:0030424"(axon)|go:"GO:0030425"(dendrite)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0033270"(paranode region of axon)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0034613"(cellular protein localization)|go:"GO:0034705"(potassium channel complex)|go:"GO:0042391"(regulation of membrane potential)|go:"GO:0042734"(presynaptic membrane)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043204"(perikaryon)|go:"GO:0043679"(axon terminus)|go:"GO:0044224"(juxtaparanode region of axon)|go:"GO:0044305"(calyx of Held)|go:"GO:0045202"(synapse)|go:"GO:0050905"(neuromuscular process)|go:"GO:0050966"(detection of mechanical stimulus involved in sensory perception of pain)|go:"GO:0050976"(detection of mechanical stimulus involved in sensory perception of touch)|go:"GO:0051260"(protein homooligomerization)|go:"GO:0071286"(cellular response to magnesium ion)|go:"GO:0071805"(potassium ion transmembrane transport)|go:"GO:0097718"(disordered domain specific binding)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099055"(integral component of postsynaptic membrane)|go:"GO:0099056"(integral component of presynaptic membrane)|go:"GO:0099508"(voltage-gated ion channel activity involved in regulation of presynaptic membrane potential)|go:"GO:1903818"(positive regulation of voltage-gated potassium channel activity)|go:"GO:1905030"(voltage-gated ion channel activity involved in regulation of postsynaptic membrane potential)|interpro:IPR000210(BTB/POZ-like)|interpro:IPR003131(Potassium channel, voltage dependent, Kv,  tetramerisation)|interpro:IPR003968(Potassium channel, voltage dependent, Kv)|interpro:IPR003972(Potassium channel, voltage dependent, Kv1)|interpro:IPR004048(Potassium channel, voltage dependent, Kv1.1)|interpro:IPR005821(Ion transport)|interpro:IPR011333(BTB/POZ fold)|interpro:IPR027359|interpro:IPR028325|mint:P10499|rcsb pdb:1EXB|reactome:R-RNO-1296072|ensembl:ENSRNOG00000019750(gene)|ensembl:ENSRNOT00000026731(transcript)|go:"GO:0001964"(startle response)|go:"GO:0005249"(voltage-gated potassium channel activity)|go:"GO:0005251"(delayed rectifier potassium channel activity)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005829"(cytosol)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006937"(regulation of muscle contraction)|go:"GO:0007405"(neuroblast proliferation)|go:"GO:0007420"(brain development)|go:"GO:0008076"(voltage-gated potassium channel complex)|go:"GO:0009986"(cell surface)|go:"GO:0010644"(cell communication by electrical coupling)|go:"GO:0010960"(magnesium ion homeostasis)|go:"GO:0016021"(integral component of membrane)	-	-	-	figure legend:st1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10116(rat-brain-cortex)|taxid:10116(Rattus norvegicus brain cortex)	-	2020/10/30	2020/10/30	rogid:DtE+ZXAZKdCMvUW5K+jXQ5bH07M10116	rogid:tGnBP9au7V54T4OD+8yaV3c0jss10116	rigid:3wclwrjZRvafcOruQOYnegkn54c	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q5XIE8	uniprotkb:Q3SWU3	intact:EBI-15348306|ensembl:ENSRNOP00000023037	intact:EBI-6122303|ensembl:ENSRNOP00000003106	psi-mi:itm2b_rat(display_long)|uniprotkb:Itm2b(gene name)|psi-mi:Itm2b(display_short)|uniprotkb:Immature BRI2(gene name synonym)|uniprotkb:Transmembrane protein BRI(gene name synonym)	psi-mi:hnrdl_rat(display_long)|uniprotkb:Hnrnpdl(gene name)|psi-mi:Hnrnpdl(display_short)|uniprotkb:Hnrpdl(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Martins et al. (2018)	imex:IM-28469|pubmed:29476059	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26439741|imex:IM-28469-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSRNOG00000016271(gene)|ensembl:ENSRNOT00000023037(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001540"(amyloid-beta binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0010008"(endosome membrane)|go:"GO:0030660"(Golgi-associated vesicle membrane)|go:"GO:0031301"(integral component of organelle membrane)|go:"GO:0042985"(negative regulation of amyloid precursor protein biosynthetic process)|interpro:IPR007084(BRICHOS)|interpro:IPR040145|mint:Q5XIE8|refseq:NP_001006964.1|rgd:620727	rgd:1309950|refseq:NP_001028868.1|ensembl:ENSRNOG00000002270(gene)|ensembl:ENSRNOT00000003106(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0008143"("poly(A) binding")|go:"GO:0010468"(regulation of gene expression)|go:"GO:0034046"("poly(G) binding")|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR034847|interpro:IPR035979|mint:Q3SWU3	-	-	-	figure legend:st1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10116(rat-brain-cortex)|taxid:10116(Rattus norvegicus brain cortex)	-	2020/10/30	2020/10/30	rogid:DtE+ZXAZKdCMvUW5K+jXQ5bH07M10116	rogid:/J4JZsZ8MmPfE59aUGI4Itm32oA10116	rigid:3wclwrjZRvafcOruQOYnegkn54c	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q5XIE8	uniprotkb:P08461	intact:EBI-15348306|ensembl:ENSRNOP00000023037	intact:EBI-916164|uniprotkb:Q3B7V7|ensembl:ENSRNOP00000032890	psi-mi:itm2b_rat(display_long)|uniprotkb:Itm2b(gene name)|psi-mi:Itm2b(display_short)|uniprotkb:Immature BRI2(gene name synonym)|uniprotkb:Transmembrane protein BRI(gene name synonym)	psi-mi:odp2_rat(display_long)|uniprotkb:Dlat(gene name)|psi-mi:Dlat(display_short)|uniprotkb:Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex(gene name synonym)|uniprotkb:Pyruvate dehydrogenase complex component E2(gene name synonym)|uniprotkb:70 kDa mitochondrial autoantigen of primary biliary cirrhosis(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Martins et al. (2018)	imex:IM-28469|pubmed:29476059	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26439741|imex:IM-28469-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSRNOG00000016271(gene)|ensembl:ENSRNOT00000023037(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001540"(amyloid-beta binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0010008"(endosome membrane)|go:"GO:0030660"(Golgi-associated vesicle membrane)|go:"GO:0031301"(integral component of organelle membrane)|go:"GO:0042985"(negative regulation of amyloid precursor protein biosynthetic process)|interpro:IPR007084(BRICHOS)|interpro:IPR040145|mint:Q5XIE8|refseq:NP_001006964.1|rgd:620727	rgd:619859|refseq:NP_112287.1|reactome:R-RNO-204174|reactome:R-RNO-389661|reactome:R-RNO-5362517|reactome:R-RNO-70268|mint:P08461|ensembl:ENSRNOG00000009994(gene)|ensembl:ENSRNOT00000032152(transcript)|go:"GO:0000166"(nucleotide binding)|go:"GO:0004742"(dihydrolipoyllysine-residue acetyltransferase activity)|go:"GO:0005739"(mitochondrion)|go:"GO:0005967"(mitochondrial pyruvate dehydrogenase complex)|go:"GO:0006006"(glucose metabolic process)|go:"GO:0006086"(acetyl-CoA biosynthetic process from pyruvate)|go:"GO:0006099"(tricarboxylic acid cycle)|go:"GO:0030431"(sleep)|go:"GO:0034604"("pyruvate dehydrogenase (NAD+) activity")|go:"GO:0042802"(identical protein binding)|go:"GO:0045254"(pyruvate dehydrogenase complex)|interpro:IPR000089(Biotin/lipoyl attachment)|interpro:IPR001078(Catalytic domain of components of various dehydrogenase complexes)|interpro:IPR003016(2-oxo acid dehydrogenase, lipoyl-binding site)|interpro:IPR004167(E3 binding)|interpro:IPR006257(Dihydrolipoamide acetyltransferase, long form)|interpro:IPR011053(Single hybrid motif)|interpro:IPR023213|interpro:IPR036625	-	-	-	figure legend:st1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10116(rat-brain-cortex)|taxid:10116(Rattus norvegicus brain cortex)	-	2020/10/30	2020/10/30	rogid:DtE+ZXAZKdCMvUW5K+jXQ5bH07M10116	rogid:XRVK9EEakONyvrLsZOP+1XhAfHA10116	rigid:3wclwrjZRvafcOruQOYnegkn54c	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q5XIE8	uniprotkb:Q8CGU4	intact:EBI-15348306|ensembl:ENSRNOP00000023037	intact:EBI-4409108|uniprotkb:Q9JHW8|ensembl:ENSRNOP00000029533	psi-mi:itm2b_rat(display_long)|uniprotkb:Itm2b(gene name)|psi-mi:Itm2b(display_short)|uniprotkb:Immature BRI2(gene name synonym)|uniprotkb:Transmembrane protein BRI(gene name synonym)	psi-mi:agap2_rat(display_long)|uniprotkb:Agap2(gene name)|psi-mi:Agap2(display_short)|uniprotkb:Centg1(gene name synonym)|uniprotkb:Centaurin-gamma-1(gene name synonym)|uniprotkb:Phosphatidylinositol 3-kinase enhancer(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Martins et al. (2018)	imex:IM-28469|pubmed:29476059	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26439741|imex:IM-28469-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSRNOG00000016271(gene)|ensembl:ENSRNOT00000023037(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001540"(amyloid-beta binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0010008"(endosome membrane)|go:"GO:0030660"(Golgi-associated vesicle membrane)|go:"GO:0031301"(integral component of organelle membrane)|go:"GO:0042985"(negative regulation of amyloid precursor protein biosynthetic process)|interpro:IPR007084(BRICHOS)|interpro:IPR040145|mint:Q5XIE8|refseq:NP_001006964.1|rgd:620727	rgd:628844|refseq:NP_075415.2|ensembl:ENSRNOG00000025584(gene)|ensembl:ENSRNOT00000031230(transcript)|go:"GO:0003924"(GTPase activity)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005525"(GTP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005829"(cytosol)|go:"GO:0014068"(positive regulation of phosphatidylinositol 3-kinase signaling)|go:"GO:0016197"(endosomal transport)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030036"(actin cytoskeleton organization)|go:"GO:0030295"(protein kinase activator activity)|go:"GO:0035014"(phosphatidylinositol 3-kinase regulator activity)|go:"GO:0042177"(negative regulation of protein catabolic process)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0045860"(positive regulation of protein kinase activity)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046427"(positive regulation of receptor signaling pathway via JAK-STAT)|go:"GO:0046872"(metal ion binding)|go:"GO:0060749"(mammary gland alveolus development)|go:"GO:0090543"(Flemming body)|go:"GO:2001240"(negative regulation of extrinsic apoptotic signaling pathway in absence of ligand)|interpro:IPR001164(Arf GTPase activating protein)|interpro:IPR001806(Ras GTPase)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR002110(Ankyrin)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR020683|interpro:IPR027417|interpro:IPR036770|interpro:IPR037278|interpro:IPR038508|mint:Q8CGU4|go:"GO:0033601"(positive regulation of mammary gland epithelial cell proliferation)	-	-	-	figure legend:st1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10116(rat-brain-cortex)|taxid:10116(Rattus norvegicus brain cortex)	-	2020/10/30	2020/10/30	rogid:DtE+ZXAZKdCMvUW5K+jXQ5bH07M10116	rogid:ag94DMSnF60z/fvBWdT0sLtYZ8M10116	rigid:3wclwrjZRvafcOruQOYnegkn54c	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q5XIE8	uniprotkb:Q6QIX3	intact:EBI-15348306|ensembl:ENSRNOP00000023037	intact:EBI-26408587|uniprotkb:Q5RJT1|ensembl:ENSRNOP00000008126	psi-mi:itm2b_rat(display_long)|uniprotkb:Itm2b(gene name)|psi-mi:Itm2b(display_short)|uniprotkb:Immature BRI2(gene name synonym)|uniprotkb:Transmembrane protein BRI(gene name synonym)	psi-mi:znt3_rat(display_long)|uniprotkb:Slc30a3(gene name)|psi-mi:Slc30a3(display_short)|uniprotkb:Solute carrier family 30 member 3(gene name synonym)|uniprotkb:Znt3(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Martins et al. (2018)	imex:IM-28469|pubmed:29476059	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26439741|imex:IM-28469-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSRNOG00000016271(gene)|ensembl:ENSRNOT00000023037(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001540"(amyloid-beta binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0010008"(endosome membrane)|go:"GO:0030660"(Golgi-associated vesicle membrane)|go:"GO:0031301"(integral component of organelle membrane)|go:"GO:0042985"(negative regulation of amyloid precursor protein biosynthetic process)|interpro:IPR007084(BRICHOS)|interpro:IPR040145|mint:Q5XIE8|refseq:NP_001006964.1|rgd:620727	refseq:NP_001013261.1|refseq:XP_008762748.1|refseq:XP_008762749.1|refseq:XP_008762750.1|rgd:1359689|ensembl:ENSRNOG00000006204(gene)|ensembl:ENSRNOT00000008126(transcript)|go:"GO:0005385"(zinc ion transmembrane transporter activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005770"(late endosome)|go:"GO:0005886"(plasma membrane)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0010043"(response to zinc ion)|go:"GO:0030285"(integral component of synaptic vesicle membrane)|go:"GO:0030672"(synaptic vesicle membrane)|go:"GO:0031902"(late endosome membrane)|go:"GO:0043005"(neuron projection)|go:"GO:0051050"(positive regulation of transport)|go:"GO:0061088"(regulation of sequestering of zinc ion)|go:"GO:0071577"(zinc ion transmembrane transport)|go:"GO:0097457"(hippocampal mossy fiber)|go:"GO:0098686"(hippocampal mossy fiber to CA3 synapse)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099180"(zinc ion import into synaptic vesicle)|interpro:IPR002524(Cation efflux protein)|interpro:IPR027469|interpro:IPR036837|mint:Q6QIX3	-	-	-	figure legend:st1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10116(rat-brain-cortex)|taxid:10116(Rattus norvegicus brain cortex)	-	2020/10/30	2020/10/30	rogid:DtE+ZXAZKdCMvUW5K+jXQ5bH07M10116	rogid:BmR7g4f1l7Wk9xAtGGWzAwcacfg10116	rigid:3wclwrjZRvafcOruQOYnegkn54c	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q5XIE8	uniprotkb:Q9ERH3	intact:EBI-15348306|ensembl:ENSRNOP00000023037	intact:EBI-26373316|ensembl:ENSRNOP00000025325|uniprotkb:Q920I8	psi-mi:itm2b_rat(display_long)|uniprotkb:Itm2b(gene name)|psi-mi:Itm2b(display_short)|uniprotkb:Immature BRI2(gene name synonym)|uniprotkb:Transmembrane protein BRI(gene name synonym)	psi-mi:wdr7_rat(display_long)|uniprotkb:TGF-beta resistance-associated protein TRAG(gene name synonym)|uniprotkb:Wdr7(gene name)|psi-mi:Wdr7(display_short)|uniprotkb:Trag(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Martins et al. (2018)	imex:IM-28469|pubmed:29476059	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26439741|imex:IM-28469-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSRNOG00000016271(gene)|ensembl:ENSRNOT00000023037(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001540"(amyloid-beta binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0010008"(endosome membrane)|go:"GO:0030660"(Golgi-associated vesicle membrane)|go:"GO:0031301"(integral component of organelle membrane)|go:"GO:0042985"(negative regulation of amyloid precursor protein biosynthetic process)|interpro:IPR007084(BRICHOS)|interpro:IPR040145|mint:Q5XIE8|refseq:NP_001006964.1|rgd:620727	ensembl:ENSRNOG00000018387(gene)|ensembl:ENSRNOT00000025325(transcript)|go:"GO:0002244"(hematopoietic progenitor cell differentiation)|go:"GO:0008021"(synaptic vesicle)|interpro:IPR001680(WD40 repeat)|interpro:IPR011047(Quinonprotein alcohol dehydrogenase-like)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019775|interpro:IPR036322|mint:Q9ERH3|rgd:619836|refseq:NP_076465.1|refseq:XP_008770393.1|refseq:XP_017456520.1	-	-	-	figure legend:st1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10116(rat-brain-cortex)|taxid:10116(Rattus norvegicus brain cortex)	-	2020/10/30	2020/10/30	rogid:DtE+ZXAZKdCMvUW5K+jXQ5bH07M10116	rogid:SVXIZzejuLszlVTI9nr8R3NqB+Q10116	rigid:3wclwrjZRvafcOruQOYnegkn54c	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q5XIE8	uniprotkb:O54715	intact:EBI-15348306|ensembl:ENSRNOP00000023037	intact:EBI-915573	psi-mi:itm2b_rat(display_long)|uniprotkb:Itm2b(gene name)|psi-mi:Itm2b(display_short)|uniprotkb:Immature BRI2(gene name synonym)|uniprotkb:Transmembrane protein BRI(gene name synonym)	psi-mi:vas1_rat(display_long)|uniprotkb:V-ATPase S1 accessory protein(gene name synonym)|uniprotkb:V-ATPase Ac45 subunit(gene name synonym)|uniprotkb:C7-1 protein(gene name synonym)|uniprotkb:Atp6ap1(gene name)|psi-mi:Atp6ap1(display_short)|uniprotkb:Atp6ip1(gene name synonym)|uniprotkb:Atp6s1(gene name synonym)|uniprotkb:Vacuolar proton pump subunit S1(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Martins et al. (2018)	imex:IM-28469|pubmed:29476059	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26439741|imex:IM-28469-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSRNOG00000016271(gene)|ensembl:ENSRNOT00000023037(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001540"(amyloid-beta binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0010008"(endosome membrane)|go:"GO:0030660"(Golgi-associated vesicle membrane)|go:"GO:0031301"(integral component of organelle membrane)|go:"GO:0042985"(negative regulation of amyloid precursor protein biosynthetic process)|interpro:IPR007084(BRICHOS)|interpro:IPR040145|mint:Q5XIE8|refseq:NP_001006964.1|rgd:620727	interpro:IPR008388(ATPase, V1 complex, subunit S1)|rgd:620423|refseq:NP_113973.1|mint:O54715|go:"GO:0005524"(ATP binding)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006879"(cellular iron ion homeostasis)|go:"GO:0007568"(aging)|go:"GO:0008219"(cell death)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030641"(regulation of cellular pH)|go:"GO:0031267"(small GTPase binding)|go:"GO:0033116"(endoplasmic reticulum-Golgi intermediate compartment membrane)|go:"GO:0033180"(proton-transporting V-type ATPase, V1 domain)|go:"GO:0033181"(plasma membrane proton-transporting V-type ATPase complex)|go:"GO:0036295"(cellular response to increased oxygen levels)|go:"GO:0045669"(positive regulation of osteoblast differentiation)|go:"GO:0045780"(positive regulation of bone resorption)|go:"GO:0045851"(pH reduction)|go:"GO:0045921"(positive regulation of exocytosis)|go:"GO:0051656"(establishment of organelle localization)|go:"GO:0070374"(positive regulation of ERK1 and ERK2 cascade)|go:"GO:1902600"(proton transmembrane transport)|go:"GO:2001206"(positive regulation of osteoclast development)|rcsb pdb:6VQ6|rcsb pdb:6VQ7|rcsb pdb:6VQ8|rcsb pdb:6VQC|rcsb pdb:6VQG|rcsb pdb:6VQH|reactome:R-RNO-77387|reactome:R-RNO-8980692|reactome:R-RNO-917977|reactome:R-RNO-983712	-	-	-	figure legend:st1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10116(rat-brain-cortex)|taxid:10116(Rattus norvegicus brain cortex)	-	2020/10/30	2020/10/30	rogid:DtE+ZXAZKdCMvUW5K+jXQ5bH07M10116	rogid:SQbhwQxTt+SDeOiaf5IuR0kMVHU10116	rigid:3wclwrjZRvafcOruQOYnegkn54c	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q5XIE8	uniprotkb:P62815	intact:EBI-15348306|ensembl:ENSRNOP00000023037	intact:EBI-772667|uniprotkb:O09045|uniprotkb:P50517|ensembl:ENSRNOP00000015931	psi-mi:itm2b_rat(display_long)|uniprotkb:Itm2b(gene name)|psi-mi:Itm2b(display_short)|uniprotkb:Immature BRI2(gene name synonym)|uniprotkb:Transmembrane protein BRI(gene name synonym)	psi-mi:vatb2_rat(display_long)|uniprotkb:Vacuolar proton pump subunit B 2(gene name synonym)|uniprotkb:Endomembrane proton pump 58 kDa subunit(gene name synonym)|uniprotkb:Atp6v1b2(gene name)|psi-mi:Atp6v1b2(display_short)|uniprotkb:Atp6b2(gene name synonym)|uniprotkb:Vat2(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Martins et al. (2018)	imex:IM-28469|pubmed:29476059	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26439741|imex:IM-28469-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSRNOG00000016271(gene)|ensembl:ENSRNOT00000023037(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001540"(amyloid-beta binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0010008"(endosome membrane)|go:"GO:0030660"(Golgi-associated vesicle membrane)|go:"GO:0031301"(integral component of organelle membrane)|go:"GO:0042985"(negative regulation of amyloid precursor protein biosynthetic process)|interpro:IPR007084(BRICHOS)|interpro:IPR040145|mint:Q5XIE8|refseq:NP_001006964.1|rgd:620727	rgd:620284|refseq:NP_476561.1|ensembl:ENSRNOG00000011891(gene)|ensembl:ENSRNOT00000015931(transcript)|go:"GO:0000221"(vacuolar proton-transporting V-type ATPase, V1 domain)|go:"GO:0001726"(ruffle)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005902"(microvillus)|go:"GO:0007035"(vacuolar acidification)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0016787"(hydrolase activity)|go:"GO:0030641"(regulation of cellular pH)|go:"GO:0042470"(melanosome)|go:"GO:0046034"(ATP metabolic process)|go:"GO:1902600"(proton transmembrane transport)|interpro:IPR000194(ATPase, F1/V1/A1 complex, alpha/beta subunit, nucleotide-binding)|interpro:IPR004100(ATPase, F1/V1/A1 complex, alpha/beta subunit, N-terminal)|interpro:IPR005723(ATPase, V1 complex, subunit B)|interpro:IPR020003|interpro:IPR022879|interpro:IPR027417|mint:P62815|rcsb pdb:6VQ6|rcsb pdb:6VQ7|rcsb pdb:6VQ8|rcsb pdb:6VQ9|rcsb pdb:6VQA|rcsb pdb:6VQB|reactome:R-RNO-1222556|reactome:R-RNO-77387|reactome:R-RNO-917977|reactome:R-RNO-9639288|reactome:R-RNO-983712	-	-	-	figure legend:st1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10116(rat-brain-cortex)|taxid:10116(Rattus norvegicus brain cortex)	-	2020/10/30	2020/10/30	rogid:DtE+ZXAZKdCMvUW5K+jXQ5bH07M10116	rogid:cmFm/xe3iOTqmy849cfoi4XeG+A10116	rigid:3wclwrjZRvafcOruQOYnegkn54c	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q5XIE8	uniprotkb:Q5J3M4	intact:EBI-15348306|ensembl:ENSRNOP00000023037	intact:EBI-26439380|ensembl:ENSRNOP00000042308	psi-mi:itm2b_rat(display_long)|uniprotkb:Itm2b(gene name)|psi-mi:Itm2b(display_short)|uniprotkb:Immature BRI2(gene name synonym)|uniprotkb:Transmembrane protein BRI(gene name synonym)	psi-mi:v1r94_rat(display_long)|uniprotkb:Vom1r94(gene name)|psi-mi:Vom1r94(display_short)|uniprotkb:V1ra13(gene name synonym)|uniprotkb:Vomeronasal type-1 receptor A13(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Martins et al. (2018)	imex:IM-28469|pubmed:29476059	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26439741|imex:IM-28469-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSRNOG00000016271(gene)|ensembl:ENSRNOT00000023037(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001540"(amyloid-beta binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0010008"(endosome membrane)|go:"GO:0030660"(Golgi-associated vesicle membrane)|go:"GO:0031301"(integral component of organelle membrane)|go:"GO:0042985"(negative regulation of amyloid precursor protein biosynthetic process)|interpro:IPR007084(BRICHOS)|interpro:IPR040145|mint:Q5XIE8|refseq:NP_001006964.1|rgd:620727	ensembl:ENSRNOG00000031140(gene)|ensembl:ENSRNOT00000049591(transcript)|go:"GO:0005886"(plasma membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016503"(pheromone receptor activity)|go:"GO:0019236"(response to pheromone)|interpro:IPR004072(Vomeronasal receptor, type 1)|interpro:IPR017452(GPCR, rhodopsin-like superfamily)|mint:Q5J3M4|rgd:1359098	-	-	-	figure legend:st1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10116(rat-brain-cortex)|taxid:10116(Rattus norvegicus brain cortex)	-	2020/10/30	2020/10/30	rogid:DtE+ZXAZKdCMvUW5K+jXQ5bH07M10116	rogid:CVcJZCr22HrLl19UsEG39gHbYfc10116	rigid:3wclwrjZRvafcOruQOYnegkn54c	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q5XIE8	uniprotkb:Q9JI12	intact:EBI-15348306|ensembl:ENSRNOP00000023037	intact:EBI-26439346	psi-mi:itm2b_rat(display_long)|uniprotkb:Itm2b(gene name)|psi-mi:Itm2b(display_short)|uniprotkb:Immature BRI2(gene name synonym)|uniprotkb:Transmembrane protein BRI(gene name synonym)	psi-mi:vglu2_rat(display_long)|uniprotkb:Slc17a6(gene name)|psi-mi:Slc17a6(display_short)|uniprotkb:Dnpi(gene name synonym)|uniprotkb:Vglut2(gene name synonym)|uniprotkb:Differentiation-associated BNPI(gene name synonym)|uniprotkb:"Differentiation-associated Na(+)-dependent inorganic phosphate cotransporter"(gene name synonym)|uniprotkb:Solute carrier family 17 member 6(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Martins et al. (2018)	imex:IM-28469|pubmed:29476059	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26439741|imex:IM-28469-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSRNOG00000016271(gene)|ensembl:ENSRNOT00000023037(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001540"(amyloid-beta binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0010008"(endosome membrane)|go:"GO:0030660"(Golgi-associated vesicle membrane)|go:"GO:0031301"(integral component of organelle membrane)|go:"GO:0042985"(negative regulation of amyloid precursor protein biosynthetic process)|interpro:IPR007084(BRICHOS)|interpro:IPR040145|mint:Q5XIE8|refseq:NP_001006964.1|rgd:620727	go:"GO:0050803"(regulation of synapse structure or activity)|go:"GO:0060076"(excitatory synapse)|go:"GO:0098700"(neurotransmitter loading into synaptic vesicle)|go:"GO:0098793"(presynapse)|go:"GO:1990030"(pericellular basket)|go:"GO:1990384"(hyaloid vascular plexus regression)|rcsb pdb:6V4D|reactome:R-RNO-428643|go:"GO:0001504"(neurotransmitter uptake)|go:"GO:0003407"(neural retina development)|go:"GO:0005313"(L-glutamate transmembrane transporter activity)|go:"GO:0005326"(neurotransmitter transmembrane transporter activity)|go:"GO:0005769"(early endosome)|go:"GO:0006814"(sodium ion transport)|go:"GO:0006820"(anion transport)|go:"GO:0007420"(brain development)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0015293"(symporter activity)|go:"GO:0016021"(integral component of membrane)|go:"GO:0021766"(hippocampus development)|go:"GO:0022857"(transmembrane transporter activity)|go:"GO:0030285"(integral component of synaptic vesicle membrane)|go:"GO:0035249"(synaptic transmission, glutamatergic)|mint:Q9JI12|refseq:NP_445879.1|interpro:IPR011701(Major facilitator superfamily MFS-1)|interpro:IPR020846|interpro:IPR036259|rgd:620531	-	-	-	figure legend:st1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10116(rat-brain-cortex)|taxid:10116(Rattus norvegicus brain cortex)	-	2020/10/30	2020/10/30	rogid:DtE+ZXAZKdCMvUW5K+jXQ5bH07M10116	rogid:drAgt0j2dzYA87MTGNR4q9ecwQ810116	rigid:3wclwrjZRvafcOruQOYnegkn54c	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q5XIE8	uniprotkb:Q63357	intact:EBI-15348306|ensembl:ENSRNOP00000023037	intact:EBI-26439296|ensembl:ENSRNOP00000004609|uniprotkb:Q5PQU2	psi-mi:itm2b_rat(display_long)|uniprotkb:Itm2b(gene name)|psi-mi:Itm2b(display_short)|uniprotkb:Immature BRI2(gene name synonym)|uniprotkb:Transmembrane protein BRI(gene name synonym)	psi-mi:myo1d_rat(display_long)|uniprotkb:Myo1d(gene name)|psi-mi:Myo1d(display_short)|uniprotkb:Myr4(gene name synonym)|uniprotkb:Myosin heavy chain myr 4(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Martins et al. (2018)	imex:IM-28469|pubmed:29476059	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26439741|imex:IM-28469-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSRNOG00000016271(gene)|ensembl:ENSRNOT00000023037(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001540"(amyloid-beta binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0010008"(endosome membrane)|go:"GO:0030660"(Golgi-associated vesicle membrane)|go:"GO:0031301"(integral component of organelle membrane)|go:"GO:0042985"(negative regulation of amyloid precursor protein biosynthetic process)|interpro:IPR007084(BRICHOS)|interpro:IPR040145|mint:Q5XIE8|refseq:NP_001006964.1|rgd:620727	ensembl:ENSRNOG00000003276(gene)|ensembl:ENSRNOT00000004609(transcript)|go:"GO:0000146"(microfilament motor activity)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005769"(early endosome)|go:"GO:0005790"(smooth endoplasmic reticulum)|go:"GO:0005886"(plasma membrane)|go:"GO:0005902"(microvillus)|go:"GO:0005903"(brush border)|go:"GO:0005938"(cell cortex)|go:"GO:0007015"(actin filament organization)|go:"GO:0015031"(protein transport)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016459"(myosin complex)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030050"(vesicle transport along actin filament)|go:"GO:0030424"(axon)|go:"GO:0030673"(axolemma)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0031982"(vesicle)|go:"GO:0043005"(neuron projection)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043204"(perikaryon)|go:"GO:0043209"(myelin sheath)|go:"GO:0044853"(plasma membrane raft)|go:"GO:0048306"(calcium-dependent protein binding)|go:"GO:0051015"(actin filament binding)|go:"GO:0051641"(cellular localization)|go:"GO:0097440"(apical dendrite)|interpro:IPR000048(IQ calmodulin-binding region)|interpro:IPR001609(Myosin head, motor region)|interpro:IPR010926(Myosin tail 2)|interpro:IPR027417|interpro:IPR036072|interpro:IPR036961|mint:Q63357|go:"GO:0030900"(forebrain development)|refseq:NP_037115.2|rgd:621321	-	-	-	figure legend:st1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10116(rat-brain-cortex)|taxid:10116(Rattus norvegicus brain cortex)	-	2020/10/30	2020/10/30	rogid:DtE+ZXAZKdCMvUW5K+jXQ5bH07M10116	rogid:/4IPaKAvofUnW1PxXnsSq5kF78M10116	rigid:3wclwrjZRvafcOruQOYnegkn54c	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q5XIE8	uniprotkb:Q68FR8	intact:EBI-15348306|ensembl:ENSRNOP00000023037	intact:EBI-26439245|ensembl:ENSRNOP00000039152|ensembl:ENSRNOP00000049998	psi-mi:itm2b_rat(display_long)|uniprotkb:Itm2b(gene name)|psi-mi:Itm2b(display_short)|uniprotkb:Immature BRI2(gene name synonym)|uniprotkb:Transmembrane protein BRI(gene name synonym)	psi-mi:tba3_rat(display_long)|uniprotkb:Tuba3a(gene name)|psi-mi:Tuba3a(display_short)|uniprotkb:Tuba3b(gene name)|psi-mi:Tuba3b(display_short)|uniprotkb:Tuba3(gene name synonym)|uniprotkb:Alpha-tubulin 3(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Martins et al. (2018)	imex:IM-28469|pubmed:29476059	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26439741|imex:IM-28469-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSRNOG00000016271(gene)|ensembl:ENSRNOT00000023037(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001540"(amyloid-beta binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0010008"(endosome membrane)|go:"GO:0030660"(Golgi-associated vesicle membrane)|go:"GO:0031301"(integral component of organelle membrane)|go:"GO:0042985"(negative regulation of amyloid precursor protein biosynthetic process)|interpro:IPR007084(BRICHOS)|interpro:IPR040145|mint:Q5XIE8|refseq:NP_001006964.1|rgd:620727	go:"GO:0005525"(GTP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005874"(microtubule)|interpro:IPR000217(Tubulin)|interpro:IPR002452(Alpha tubulin)|interpro:IPR003008(Tubulin/FtsZ, GTPase)|interpro:IPR008280(Tubulin/FtsZ, C-terminal)|interpro:IPR017975|interpro:IPR018316|interpro:IPR023123|interpro:IPR036525|interpro:IPR037103|mint:Q68FR8|reactome:R-RNO-190840|reactome:R-RNO-2132295|reactome:R-RNO-2467813|reactome:R-RNO-2500257|reactome:R-RNO-3371497|reactome:R-RNO-380320|reactome:R-RNO-437239|reactome:R-RNO-5610787|reactome:R-RNO-5617833|reactome:R-RNO-5620924|reactome:R-RNO-5626467|go:"GO:0005200"(structural constituent of cytoskeleton)|reactome:R-RNO-5663220|reactome:R-RNO-6807878|reactome:R-RNO-6811434|reactome:R-RNO-6811436|reactome:R-RNO-68877|reactome:R-RNO-8852276|reactome:R-RNO-8955332|reactome:R-RNO-9646399|reactome:R-RNO-9648025|reactome:R-RNO-9668328|reactome:R-RNO-983189|ensembl:ENSRNOG00000031707(gene)|ensembl:ENSRNOG00000032967(gene)|ensembl:ENSRNOT00000044425(transcript)|ensembl:ENSRNOT00000052352(transcript)|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0000278"(mitotic cell cycle)|refseq:NP_001019507.1|refseq:NP_001035097.1|rgd:1565155|rgd:1565719	-	-	-	figure legend:st1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10116(rat-brain-cortex)|taxid:10116(Rattus norvegicus brain cortex)	-	2020/10/30	2020/10/30	rogid:DtE+ZXAZKdCMvUW5K+jXQ5bH07M10116	rogid:mE1Hcdc9AAMMxfxzKB6TfM6RrHE10116	rigid:3wclwrjZRvafcOruQOYnegkn54c	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q5XIE8	uniprotkb:Q63610	intact:EBI-15348306|ensembl:ENSRNOP00000023037	intact:EBI-1374845|uniprotkb:Q63599|uniprotkb:Q63600|uniprotkb:Q63601|ensembl:ENSRNOP00000023567	psi-mi:itm2b_rat(display_long)|uniprotkb:Itm2b(gene name)|psi-mi:Itm2b(display_short)|uniprotkb:Immature BRI2(gene name synonym)|uniprotkb:Transmembrane protein BRI(gene name synonym)	psi-mi:tpm3_rat(display_long)|uniprotkb:Tpm3(gene name)|psi-mi:Tpm3(display_short)|uniprotkb:Tpm5(gene name synonym)|uniprotkb:Tpm-5(gene name synonym)|uniprotkb:Tropomyosin-3(gene name synonym)|uniprotkb:Gamma-tropomyosin(gene name synonym)|uniprotkb:Tropomyosin-5(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Martins et al. (2018)	imex:IM-28469|pubmed:29476059	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26439741|imex:IM-28469-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSRNOG00000016271(gene)|ensembl:ENSRNOT00000023037(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001540"(amyloid-beta binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0010008"(endosome membrane)|go:"GO:0030660"(Golgi-associated vesicle membrane)|go:"GO:0031301"(integral component of organelle membrane)|go:"GO:0042985"(negative regulation of amyloid precursor protein biosynthetic process)|interpro:IPR007084(BRICHOS)|interpro:IPR040145|mint:Q5XIE8|refseq:NP_001006964.1|rgd:620727	refseq:NP_001288215.1|rgd:621546|refseq:NP_476556.2|refseq:NP_775134.1|ensembl:ENSRNOG00000017441(gene)|ensembl:ENSRNOT00000023567(transcript)|go:"GO:0001725"(stress fiber)|go:"GO:0002102"(podosome)|go:"GO:0005737"(cytoplasm)|go:"GO:0005884"(actin filament)|go:"GO:0005903"(brush border)|go:"GO:0006936"(muscle contraction)|go:"GO:0007015"(actin filament organization)|go:"GO:0007420"(brain development)|go:"GO:0030426"(growth cone)|go:"GO:0030863"(cortical cytoskeleton)|go:"GO:0032154"(cleavage furrow)|go:"GO:0043005"(neuron projection)|go:"GO:0051015"(actin filament binding)|interpro:IPR000533(Tropomyosin)|interpro:IPR014751(DNA double-strand break repair and VJ recombination XRCC4, C-terminal)|mint:Q63610	-	-	-	figure legend:st1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10116(rat-brain-cortex)|taxid:10116(Rattus norvegicus brain cortex)	-	2020/10/30	2020/10/30	rogid:DtE+ZXAZKdCMvUW5K+jXQ5bH07M10116	rogid:XHAZCusR15h8uFhXleR0wPakhZY10116	rigid:3wclwrjZRvafcOruQOYnegkn54c	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q5XIE8	uniprotkb:P48500	intact:EBI-15348306|ensembl:ENSRNOP00000023037	intact:EBI-917606|uniprotkb:A0JN18|uniprotkb:Q6P793|ensembl:ENSRNOP00000020647|ensembl:ENSRNOP00000067409	psi-mi:itm2b_rat(display_long)|uniprotkb:Itm2b(gene name)|psi-mi:Itm2b(display_short)|uniprotkb:Immature BRI2(gene name synonym)|uniprotkb:Transmembrane protein BRI(gene name synonym)	psi-mi:tpis_rat(display_long)|uniprotkb:Triose-phosphate isomerase(gene name synonym)|uniprotkb:Tpi1(gene name)|psi-mi:Tpi1(display_short)|uniprotkb:Methylglyoxal synthase(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Martins et al. (2018)	imex:IM-28469|pubmed:29476059	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26439741|imex:IM-28469-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSRNOG00000016271(gene)|ensembl:ENSRNOT00000023037(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001540"(amyloid-beta binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0010008"(endosome membrane)|go:"GO:0030660"(Golgi-associated vesicle membrane)|go:"GO:0031301"(integral component of organelle membrane)|go:"GO:0042985"(negative regulation of amyloid precursor protein biosynthetic process)|interpro:IPR007084(BRICHOS)|interpro:IPR040145|mint:Q5XIE8|refseq:NP_001006964.1|rgd:620727	rgd:3896|refseq:NP_075211.2|ensembl:ENSRNOG00000015290(gene)|ensembl:ENSRNOG00000050669(gene)|ensembl:ENSRNOT00000020647(transcript)|ensembl:ENSRNOT00000071439(transcript)|go:"GO:0004807"(triose-phosphate isomerase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0005975"(carbohydrate metabolic process)|go:"GO:0006006"(glucose metabolic process)|go:"GO:0006094"(gluconeogenesis)|go:"GO:0006096"(glycolytic process)|go:"GO:0008929"(methylglyoxal synthase activity)|go:"GO:0016853"(isomerase activity)|go:"GO:0019242"(methylglyoxal biosynthetic process)|go:"GO:0019563"(glycerol catabolic process)|go:"GO:0019682"(glyceraldehyde-3-phosphate metabolic process)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0046166"(glyceraldehyde-3-phosphate biosynthetic process)|interpro:IPR000652(Triosephosphate isomerase)|interpro:IPR013785(Aldolase-type TIM barrel)|interpro:IPR020861|interpro:IPR022896|interpro:IPR035990|mint:P48500|reactome:R-RNO-70171|reactome:R-RNO-70263	-	-	-	figure legend:st1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10116(rat-brain-cortex)|taxid:10116(Rattus norvegicus brain cortex)	-	2020/10/30	2020/10/30	rogid:DtE+ZXAZKdCMvUW5K+jXQ5bH07M10116	rogid:W10iJfxiYxwYl5C2aji6DCDhpBc10116	rigid:3wclwrjZRvafcOruQOYnegkn54c	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q5XIE8	uniprotkb:Q64428	intact:EBI-15348306|ensembl:ENSRNOP00000023037	intact:EBI-299533|ensembl:ENSRNOP00000038073|uniprotkb:Q5BIZ5	psi-mi:itm2b_rat(display_long)|uniprotkb:Itm2b(gene name)|psi-mi:Itm2b(display_short)|uniprotkb:Immature BRI2(gene name synonym)|uniprotkb:Transmembrane protein BRI(gene name synonym)	psi-mi:echa_rat(display_long)|uniprotkb:Hadha(gene name)|psi-mi:Hadha(display_short)|uniprotkb:TP-alpha(gene name synonym)|uniprotkb:Monolysocardiolipin acyltransferase(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Martins et al. (2018)	imex:IM-28469|pubmed:29476059	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26439741|imex:IM-28469-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSRNOG00000016271(gene)|ensembl:ENSRNOT00000023037(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001540"(amyloid-beta binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0010008"(endosome membrane)|go:"GO:0030660"(Golgi-associated vesicle membrane)|go:"GO:0031301"(integral component of organelle membrane)|go:"GO:0042985"(negative regulation of amyloid precursor protein biosynthetic process)|interpro:IPR007084(BRICHOS)|interpro:IPR040145|mint:Q5XIE8|refseq:NP_001006964.1|rgd:620727	ensembl:ENSRNOG00000024629(gene)|ensembl:ENSRNOT00000038649(transcript)|go:"GO:0000062"(fatty-acyl-CoA binding)|go:"GO:0003857"(3-hydroxyacyl-CoA dehydrogenase activity)|go:"GO:0003988"(acetyl-CoA C-acyltransferase activity)|go:"GO:0004300"(enoyl-CoA hydratase activity)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0016507"(mitochondrial fatty acid beta-oxidation multienzyme complex)|go:"GO:0016508"(long-chain-enoyl-CoA hydratase activity)|go:"GO:0016509"(long-chain-3-hydroxyacyl-CoA dehydrogenase activity)|go:"GO:0032868"(response to insulin)|go:"GO:0006635"(fatty acid beta-oxidation)|go:"GO:0035965"(cardiolipin acyl-chain remodeling)|go:"GO:0042493"|go:"GO:0042645"(mitochondrial nucleoid)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0051287"(NAD binding)|go:"GO:0070403"(NAD+ binding)|interpro:IPR001753(Crotonase, core)|interpro:IPR006108(3-hydroxyacyl-CoA dehydrogenase, C-terminal)|interpro:IPR006176(3-hydroxyacyl-CoA dehydrogenase, NAD binding)|interpro:IPR006180(3-hydroxyacyl-CoA dehydrogenase, conserved site)|interpro:IPR008927(6-phosphogluconate dehydrogenase, C-terminal-like)|interpro:IPR012803(Fatty acid oxidation complex, alpha subunit, mitochondrial)|interpro:IPR018376|interpro:IPR029045|interpro:IPR036291|mint:Q64428|reactome:R-RNO-1482798|reactome:R-RNO-77285|reactome:R-RNO-77305|reactome:R-RNO-77310|reactome:R-RNO-77346|reactome:R-RNO-77348|reactome:R-RNO-77350|rgd:620512|refseq:NP_570839.2	-	-	-	figure legend:st1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10116(rat-brain-cortex)|taxid:10116(Rattus norvegicus brain cortex)	-	2020/10/30	2020/10/30	rogid:DtE+ZXAZKdCMvUW5K+jXQ5bH07M10116	rogid:29/8oipQMyGrNmdN1GK1cIzyNFU10116	rigid:3wclwrjZRvafcOruQOYnegkn54c	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q5XIE8	uniprotkb:P32851	intact:EBI-15348306|ensembl:ENSRNOP00000023037	intact:EBI-539720|ensembl:ENSRNOP00000040699	psi-mi:itm2b_rat(display_long)|uniprotkb:Itm2b(gene name)|psi-mi:Itm2b(display_short)|uniprotkb:Immature BRI2(gene name synonym)|uniprotkb:Transmembrane protein BRI(gene name synonym)	psi-mi:stx1a_rat(display_long)|uniprotkb:Synaptotagmin-associated 35 kDa protein(gene name synonym)|uniprotkb:Neuron-specific antigen HPC-1(gene name synonym)|uniprotkb:Stx1a(gene name)|psi-mi:Stx1a(display_short)|uniprotkb:Sap(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Martins et al. (2018)	imex:IM-28469|pubmed:29476059	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26439741|imex:IM-28469-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSRNOG00000016271(gene)|ensembl:ENSRNOT00000023037(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001540"(amyloid-beta binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0010008"(endosome membrane)|go:"GO:0030660"(Golgi-associated vesicle membrane)|go:"GO:0031301"(integral component of organelle membrane)|go:"GO:0042985"(negative regulation of amyloid precursor protein biosynthetic process)|interpro:IPR007084(BRICHOS)|interpro:IPR040145|mint:Q5XIE8|refseq:NP_001006964.1|rgd:620727	rgd:69430|refseq:NP_446240.2|rcsb pdb:5W5C|rcsb pdb:5W5D|rcsb pdb:6IP1|rcsb pdb:6MDM|rcsb pdb:6MDN|rcsb pdb:6MTI|rcsb pdb:6WVW|reactome:R-RNO-181429|reactome:R-RNO-181430|reactome:R-RNO-210500|reactome:R-RNO-212676|reactome:R-RNO-264642|reactome:R-RNO-449836|reactome:R-RNO-5682910|reactome:R-RNO-888590|reactome:R-RNO-9609523|ensembl:ENSRNOG00000029165(gene)|go:"GO:0001669"(acrosomal vesicle)|go:"GO:0001956"(positive regulation of neurotransmitter secretion)|ensembl:ENSRNOT00000049601(transcript)|go:"GO:0005484"(SNAP receptor activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006836"(neurotransmitter transport)|go:"GO:0000149"(SNARE binding)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006887"(exocytosis)|go:"GO:0006906"(vesicle fusion)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0009629"(response to gravity)|go:"GO:0010701"(positive regulation of norepinephrine secretion)|go:"GO:0010807"(regulation of synaptic vesicle priming)|go:"GO:0012505"(endomembrane system)|go:"GO:0014069"(postsynaptic density)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016079"(synaptic vesicle exocytosis)|go:"GO:0016081"(synaptic vesicle docking)|go:"GO:0016925"(protein sumoylation)|go:"GO:0017022"(myosin binding)|go:"GO:0017156"(calcium-ion regulated exocytosis)|go:"GO:0017157"(regulation of exocytosis)|go:"GO:0019855"(calcium channel inhibitor activity)|go:"GO:0019869"(chloride channel inhibitor activity)|go:"GO:0019900"(kinase binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030073"(insulin secretion)|go:"GO:0030141"(secretory granule)|go:"GO:0030285"(integral component of synaptic vesicle membrane)|go:"GO:0030424"(axon)|go:"GO:0030672"(synaptic vesicle membrane)|go:"GO:0030674"(protein-macromolecule adaptor activity)|go:"GO:0031201"(SNARE complex)|go:"GO:0031629"(synaptic vesicle fusion to presynaptic active zone membrane)|go:"GO:0031965"(nuclear membrane)|go:"GO:0032028"(myosin head/neck binding)|go:"GO:0032940"(secretion by cell)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033605"(positive regulation of catecholamine secretion)|go:"GO:0035493"(SNARE complex assembly)|go:"GO:0042641"(actomyosin)|go:"GO:0042734"(presynaptic membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0043005"(neuron projection)|go:"GO:0043008"(ATP-dependent protein binding)|go:"GO:0043229"(intracellular organelle)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045055"(regulated exocytosis)|go:"GO:0045921"(positive regulation of exocytosis)|go:"GO:0045956"(positive regulation of calcium ion-dependent exocytosis)|go:"GO:0046879"(hormone secretion)|go:"GO:0047485"(protein N-terminus binding)|go:"GO:0048278"(vesicle docking)|go:"GO:0048306"(calcium-dependent protein binding)|go:"GO:0048488"(synaptic vesicle endocytosis)|go:"GO:0048787"(presynaptic active zone membrane)|go:"GO:0070032"(synaptobrevin 2-SNAP-25-syntaxin-1a-complexin I complex)|go:"GO:0070033"(synaptobrevin 2-SNAP-25-syntaxin-1a-complexin II complex)|go:"GO:0070044"(synaptobrevin 2-SNAP-25-syntaxin-1a complex)|go:"GO:0072657"(protein localization to membrane)|go:"GO:0098815"(modulation of excitatory postsynaptic potential)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099056"(integral component of presynaptic membrane)|go:"GO:2000463"(positive regulation of excitatory postsynaptic potential)|interpro:IPR000727(Target SNARE coiled-coil region)|interpro:IPR006011(Syntaxin, N-terminal)|interpro:IPR006012(Syntaxin/epimorphin, conserved site)|interpro:IPR010989(t-SNARE)|interpro:IPR028669|go:"GO:0044325"(transmembrane transporter binding)|rcsb pdb:1BR0|rcsb pdb:1EZ3|rcsb pdb:1HVV|rcsb pdb:1JTH|rcsb pdb:1KIL|rcsb pdb:1N7S|rcsb pdb:1SFC|rcsb pdb:1URQ|rcsb pdb:2BU0|rcsb pdb:2M8R|rcsb pdb:2N1T|rcsb pdb:3C98|rcsb pdb:3HD7|rcsb pdb:3IPD|rcsb pdb:3J96|rcsb pdb:3J97|rcsb pdb:3J98|rcsb pdb:3J99|rcsb pdb:3RK2|rcsb pdb:3RK3|rcsb pdb:3RL0|rcsb pdb:4JEH|rcsb pdb:4JEU|rcsb pdb:5CCG|rcsb pdb:5CCH|mint:P32851|rcsb pdb:5CCI|rcsb pdb:5KJ7|rcsb pdb:5KJ8|dip:DIP-108N	-	-	-	figure legend:st1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10116(rat-brain-cortex)|taxid:10116(Rattus norvegicus brain cortex)	-	2020/10/30	2020/10/30	rogid:DtE+ZXAZKdCMvUW5K+jXQ5bH07M10116	rogid:2YT66D4HEHmgdiM1iy3NvlTJpVo10116	rigid:3wclwrjZRvafcOruQOYnegkn54c	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q5XIE8	uniprotkb:Q9Z327	intact:EBI-15348306|ensembl:ENSRNOP00000023037	intact:EBI-16221517	psi-mi:itm2b_rat(display_long)|uniprotkb:Itm2b(gene name)|psi-mi:Itm2b(display_short)|uniprotkb:Immature BRI2(gene name synonym)|uniprotkb:Transmembrane protein BRI(gene name synonym)	psi-mi:synpo_rat(display_long)|uniprotkb:Synpo(gene name)|psi-mi:Synpo(display_short)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Martins et al. (2018)	imex:IM-28469|pubmed:29476059	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26439741|imex:IM-28469-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSRNOG00000016271(gene)|ensembl:ENSRNOT00000023037(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001540"(amyloid-beta binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0010008"(endosome membrane)|go:"GO:0030660"(Golgi-associated vesicle membrane)|go:"GO:0031301"(integral component of organelle membrane)|go:"GO:0042985"(negative regulation of amyloid precursor protein biosynthetic process)|interpro:IPR007084(BRICHOS)|interpro:IPR040145|mint:Q5XIE8|refseq:NP_001006964.1|rgd:620727	go:"GO:0001725"(stress fiber)|go:"GO:0003779"(actin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0005923"(bicellular tight junction)|go:"GO:0008542"(visual learning)|go:"GO:0014069"(postsynaptic density)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0030018"(Z disc)|go:"GO:0032233"(positive regulation of actin filament bundle assembly)|go:"GO:0043204"(perikaryon)|go:"GO:0048169"(regulation of long-term neuronal synaptic plasticity)|go:"GO:0051492"(regulation of stress fiber assembly)|go:"GO:0071944"(cell periphery)|go:"GO:0097444"(spine apparatus)|go:"GO:0098685"(Schaffer collateral - CA1 synapse)|go:"GO:0098886"(modification of dendritic spine)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099170"(postsynaptic modulation of chemical synaptic transmission)|go:"GO:0099588"(positive regulation of postsynaptic cytosolic calcium concentration)|go:"GO:1905355"(spine apparatus assembly)|mint:Q9Z327|refseq:NP_067727.2|refseq:XP_017456508.1|interpro:IPR028753|rgd:620668	-	-	-	figure legend:st1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10116(rat-brain-cortex)|taxid:10116(Rattus norvegicus brain cortex)	-	2020/10/30	2020/10/30	rogid:DtE+ZXAZKdCMvUW5K+jXQ5bH07M10116	rogid:NG1rkzQZs0ONDqTAgjvgYRuM84k10116	rigid:3wclwrjZRvafcOruQOYnegkn54c	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q5XIE8	uniprotkb:Q63537	intact:EBI-15348306|ensembl:ENSRNOP00000023037	intact:EBI-1638355|uniprotkb:Q9Z1H0	psi-mi:itm2b_rat(display_long)|uniprotkb:Itm2b(gene name)|psi-mi:Itm2b(display_short)|uniprotkb:Immature BRI2(gene name synonym)|uniprotkb:Transmembrane protein BRI(gene name synonym)	psi-mi:syn2_rat(display_long)|uniprotkb:Syn2(gene name)|psi-mi:Syn2(display_short)|uniprotkb:Synapsin II(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Martins et al. (2018)	imex:IM-28469|pubmed:29476059	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26439741|imex:IM-28469-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSRNOG00000016271(gene)|ensembl:ENSRNOT00000023037(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001540"(amyloid-beta binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0010008"(endosome membrane)|go:"GO:0030660"(Golgi-associated vesicle membrane)|go:"GO:0031301"(integral component of organelle membrane)|go:"GO:0042985"(negative regulation of amyloid precursor protein biosynthetic process)|interpro:IPR007084(BRICHOS)|interpro:IPR040145|mint:Q5XIE8|refseq:NP_001006964.1|rgd:620727	rgd:3798|refseq:NP_001029192.1|refseq:NP_062032.1|interpro:IPR013815(ATP-grasp fold, subdomain 1)|interpro:IPR016185(PreATP-grasp-like fold)|interpro:IPR001359(Synapsin)|interpro:IPR020898|interpro:IPR019735|interpro:IPR019736|interpro:IPR020897|mint:Q63537|interpro:IPR028712|go:"GO:0005524"(ATP binding)|go:"GO:0005886"(plasma membrane)|go:"GO:0007269"(neurotransmitter secretion)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0008092"(cytoskeletal protein binding)|go:"GO:0014069"(postsynaptic density)|go:"GO:0017156"(calcium-ion regulated exocytosis)|go:"GO:0030672"(synaptic vesicle membrane)|go:"GO:0031201"(SNARE complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0043195"(terminal bouton)|go:"GO:0045202"(synapse)|go:"GO:0046928"(regulation of neurotransmitter secretion)|go:"GO:0048306"(calcium-dependent protein binding)|go:"GO:0097091"(synaptic vesicle clustering)|go:"GO:0098685"(Schaffer collateral - CA1 synapse)|go:"GO:0098850"(extrinsic component of synaptic vesicle membrane)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099504"(synaptic vesicle cycle)|rcsb pdb:1I7L|rcsb pdb:1I7N|reactome:R-RNO-181429|reactome:R-RNO-212676	-	-	-	figure legend:st1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10116(rat-brain-cortex)|taxid:10116(Rattus norvegicus brain cortex)	-	2020/10/30	2020/10/30	rogid:DtE+ZXAZKdCMvUW5K+jXQ5bH07M10116	rogid:/uqCXVO2VdZfAgfc9c8dwJQcUOY10116	rigid:3wclwrjZRvafcOruQOYnegkn54c	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q5XIE8	uniprotkb:Q4FZT0	intact:EBI-15348306|ensembl:ENSRNOP00000023037	intact:EBI-920472|ensembl:ENSRNOP00000013151	psi-mi:itm2b_rat(display_long)|uniprotkb:Itm2b(gene name)|psi-mi:Itm2b(display_short)|uniprotkb:Immature BRI2(gene name synonym)|uniprotkb:Transmembrane protein BRI(gene name synonym)	psi-mi:stml2_rat(display_long)|uniprotkb:Stoml2(gene name)|psi-mi:Stoml2(display_short)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Martins et al. (2018)	imex:IM-28469|pubmed:29476059	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26439741|imex:IM-28469-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSRNOG00000016271(gene)|ensembl:ENSRNOT00000023037(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001540"(amyloid-beta binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0010008"(endosome membrane)|go:"GO:0030660"(Golgi-associated vesicle membrane)|go:"GO:0031301"(integral component of organelle membrane)|go:"GO:0042985"(negative regulation of amyloid precursor protein biosynthetic process)|interpro:IPR007084(BRICHOS)|interpro:IPR040145|mint:Q5XIE8|refseq:NP_001006964.1|rgd:620727	rgd:1308285|refseq:NP_001026816.1|ensembl:ENSRNOG00000009535(gene)|ensembl:ENSRNOT00000013151(transcript)|go:"GO:0001772"(immunological synapse)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005758"(mitochondrial intermembrane space)|go:"GO:0006851"(mitochondrial calcium ion transmembrane transport)|go:"GO:0006874"(cellular calcium ion homeostasis)|go:"GO:0007005"(mitochondrion organization)|go:"GO:0008180"(COP9 signalosome)|go:"GO:0010876"(lipid localization)|go:"GO:0010918"(positive regulation of mitochondrial membrane potential)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0019897"(extrinsic component of plasma membrane)|go:"GO:0032743"(positive regulation of interleukin-2 production)|go:"GO:0034982"(mitochondrial protein processing)|go:"GO:0035710"(CD4-positive, alpha-beta T cell activation)|go:"GO:0042101"(T cell receptor complex)|go:"GO:0042776"(mitochondrial ATP synthesis coupled proton transport)|go:"GO:0045121"(membrane raft)|go:"GO:0050852"(T cell receptor signaling pathway)|go:"GO:0051020"(GTPase binding)|go:"GO:0051259"(protein complex oligomerization)|go:"GO:0090297"(positive regulation of mitochondrial DNA replication)|go:"GO:1900210"(positive regulation of cardiolipin metabolic process)|go:"GO:1901612"(cardiolipin binding)|go:"GO:1990046"(stress-induced mitochondrial fusion)|interpro:IPR001107(Band 7 protein)|interpro:IPR001972(Stomatin)|interpro:IPR032435|interpro:IPR036013|mint:Q4FZT0|reactome:R-RNO-8949664	-	-	-	figure legend:st1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10116(rat-brain-cortex)|taxid:10116(Rattus norvegicus brain cortex)	-	2020/10/30	2020/10/30	rogid:DtE+ZXAZKdCMvUW5K+jXQ5bH07M10116	rogid:tDZvRMTK92HMAD3z043Eb3hAKlI10116	rigid:3wclwrjZRvafcOruQOYnegkn54c	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q5XIE8	uniprotkb:P06686	intact:EBI-15348306|ensembl:ENSRNOP00000023037	intact:EBI-2649928|ensembl:ENSRNOP00000054947	psi-mi:itm2b_rat(display_long)|uniprotkb:Itm2b(gene name)|psi-mi:Itm2b(display_short)|uniprotkb:Immature BRI2(gene name synonym)|uniprotkb:Transmembrane protein BRI(gene name synonym)	psi-mi:at1a2_rat(display_long)|uniprotkb:Atp1a2(gene name)|psi-mi:Atp1a2(display_short)|uniprotkb:Sodium pump subunit alpha-2(gene name synonym)|uniprotkb:"Na(+)/K(+) ATPase alpha(+) subunit"(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Martins et al. (2018)	imex:IM-28469|pubmed:29476059	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26439741|imex:IM-28469-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSRNOG00000016271(gene)|ensembl:ENSRNOT00000023037(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001540"(amyloid-beta binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0010008"(endosome membrane)|go:"GO:0030660"(Golgi-associated vesicle membrane)|go:"GO:0031301"(integral component of organelle membrane)|go:"GO:0042985"(negative regulation of amyloid precursor protein biosynthetic process)|interpro:IPR007084(BRICHOS)|interpro:IPR040145|mint:Q5XIE8|refseq:NP_001006964.1|rgd:620727	rgd:2168|refseq:NP_036637.1|go:"GO:0005391"("P-type sodium:potassium-exchanging transporter activity")|go:"GO:0005496"(steroid binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005886"(plasma membrane)|go:"GO:0005890"("sodium:potassium-exchanging ATPase complex")|go:"GO:0005901"(caveola)|go:"GO:0006813"(potassium ion transport)|go:"GO:0006814"(sodium ion transport)|go:"GO:0006883"(cellular sodium ion homeostasis)|go:"GO:0006937"(regulation of muscle contraction)|go:"GO:0006940"(regulation of smooth muscle contraction)|go:"GO:0006942"(regulation of striated muscle contraction)|go:"GO:0008217"(regulation of blood pressure)|go:"GO:0008344"(adult locomotory behavior)|go:"GO:0008542"(visual learning)|go:"GO:0010882"(regulation of cardiac muscle contraction by calcium ion signaling)|go:"GO:0010996"(response to auditory stimulus)|go:"GO:0014704"(intercalated disc)|go:"GO:0015988"(energy coupled proton transmembrane transport, against electrochemical gradient)|go:"GO:0016020"(membrane)|go:"GO:0019229"(regulation of vasoconstriction)|go:"GO:0019829"(ATPase-coupled cation transmembrane transporter activity)|go:"GO:0021764"(amygdala development)|go:"GO:0021989"(olfactory cortex development)|go:"GO:0030007"(cellular potassium ion homeostasis)|go:"GO:0030315"(T-tubule)|go:"GO:0030955"(potassium ion binding)|go:"GO:0031090"(organelle membrane)|go:"GO:0031402"(sodium ion binding)|go:"GO:0035094"(response to nicotine)|go:"GO:0035641"(locomotory exploration behavior)|go:"GO:0002087"(regulation of respiratory gaseous exchange by nervous system process)|go:"GO:0036376"(sodium ion export across plasma membrane)|go:"GO:0040011"(locomotion)|go:"GO:0042383"(sarcolemma)|go:"GO:0042995"(cell projection)|go:"GO:0043005"(neuron projection)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043197"(dendritic spine)|go:"GO:0045202"(synapse)|go:"GO:0045822"(negative regulation of heart contraction)|go:"GO:0045988"(negative regulation of striated muscle contraction)|go:"GO:0046034"(ATP metabolic process)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0051087"(chaperone binding)|go:"GO:0051481"(negative regulation of cytosolic calcium ion concentration)|go:"GO:0055119"(relaxation of cardiac muscle)|go:"GO:0060048"(cardiac muscle contraction)|go:"GO:0071260"(cellular response to mechanical stimulus)|go:"GO:0071383"(cellular response to steroid hormone stimulus)|go:"GO:0071805"(potassium ion transmembrane transport)|go:"GO:0086004"(regulation of cardiac muscle cell contraction)|go:"GO:0098655"(cation transmembrane transport)|go:"GO:1902600"(proton transmembrane transport)|go:"GO:1903170"(negative regulation of calcium ion transmembrane transport)|go:"GO:1903280"("negative regulation of calcium:sodium antiporter activity")|go:"GO:1903416"(response to glycoside)|go:"GO:1990239"(steroid hormone binding)|go:"GO:1990573"(potassium ion import across plasma membrane)|interpro:IPR001757(ATPase, P-type, K/Mg/Cd/Cu/Zn/Na/Ca/Na/H-transporter)|interpro:IPR004014(ATPase, P-type cation-transporter, N-terminal)|interpro:IPR005775(ATPase, P-type cation exchange, alpha subunit, eukaryotic)|interpro:IPR006068(ATPase, P-type cation-transporter, C-terminal)|interpro:IPR008250(E1-E2 ATPase-associated region)|interpro:IPR018303|interpro:IPR023214|interpro:IPR023298|interpro:IPR023299|interpro:IPR036412|interpro:IPR044492|mint:P06686|reactome:R-RNO-5578775|reactome:R-RNO-936837|go:"GO:0035725"(sodium ion transmembrane transport)|ensembl:ENSRNOG00000007290(gene)|ensembl:ENSRNOT00000058143(transcript)|go:"GO:0001504"(neurotransmitter uptake)|go:"GO:0001662"(behavioral fear response)|go:"GO:0002026"(regulation of the force of heart contraction)	-	-	-	figure legend:st1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10116(rat-brain-cortex)|taxid:10116(Rattus norvegicus brain cortex)	-	2020/10/30	2020/10/30	rogid:DtE+ZXAZKdCMvUW5K+jXQ5bH07M10116	rogid:yqGZ7/62LfbJw7393x9xzZI6+K010116	rigid:3wclwrjZRvafcOruQOYnegkn54c	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q5XIE8	uniprotkb:P06685	intact:EBI-15348306|ensembl:ENSRNOP00000023037	intact:EBI-915951|uniprotkb:Q64609|ensembl:ENSRNOP00000045650	psi-mi:itm2b_rat(display_long)|uniprotkb:Itm2b(gene name)|psi-mi:Itm2b(display_short)|uniprotkb:Immature BRI2(gene name synonym)|uniprotkb:Transmembrane protein BRI(gene name synonym)	psi-mi:at1a1_rat(display_long)|uniprotkb:Atp1a1(gene name)|psi-mi:Atp1a1(display_short)|uniprotkb:Sodium pump subunit alpha-1(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Martins et al. (2018)	imex:IM-28469|pubmed:29476059	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26439741|imex:IM-28469-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSRNOG00000016271(gene)|ensembl:ENSRNOT00000023037(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001540"(amyloid-beta binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0010008"(endosome membrane)|go:"GO:0030660"(Golgi-associated vesicle membrane)|go:"GO:0031301"(integral component of organelle membrane)|go:"GO:0042985"(negative regulation of amyloid precursor protein biosynthetic process)|interpro:IPR007084(BRICHOS)|interpro:IPR040145|mint:Q5XIE8|refseq:NP_001006964.1|rgd:620727	rgd:2167|refseq:NP_036636.1|ensembl:ENSRNOG00000030019(gene)|ensembl:ENSRNOT00000040430(transcript)|go:"GO:0002026"(regulation of the force of heart contraction)|go:"GO:0002028"(regulation of sodium ion transport)|go:"GO:0005391"("P-type sodium:potassium-exchanging transporter activity")|go:"GO:0005524"(ATP binding)|go:"GO:0005768"(endosome)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0005890"("sodium:potassium-exchanging ATPase complex")|go:"GO:0005901"(caveola)|go:"GO:0006813"(potassium ion transport)|go:"GO:0006814"(sodium ion transport)|go:"GO:0006883"(cellular sodium ion homeostasis)|go:"GO:0008217"(regulation of blood pressure)|go:"GO:0010248"(establishment or maintenance of transmembrane electrochemical gradient)|go:"GO:0014069"(postsynaptic density)|go:"GO:0014704"(intercalated disc)|go:"GO:0015988"(energy coupled proton transmembrane transport, against electrochemical gradient)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0016328"(lateral plasma membrane)|go:"GO:0016791"(phosphatase activity)|go:"GO:0019901"(protein kinase binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030007"(cellular potassium ion homeostasis)|go:"GO:0030315"(T-tubule)|go:"GO:0030424"(axon)|go:"GO:0030506"(ankyrin binding)|go:"GO:0030955"(potassium ion binding)|go:"GO:0031090"(organelle membrane)|go:"GO:0031402"(sodium ion binding)|go:"GO:0031947"(negative regulation of glucocorticoid biosynthetic process)|go:"GO:0032991"(protein-containing complex)|go:"GO:0036126"(sperm flagellum)|go:"GO:0036376"(sodium ion export across plasma membrane)|go:"GO:0042383"(sarcolemma)|go:"GO:0042470"(melanosome)|go:"GO:0042493"|go:"GO:0043531"(ADP binding)|go:"GO:0043548"(phosphatidylinositol 3-kinase binding)|go:"GO:0045121"(membrane raft)|go:"GO:0045822"(negative regulation of heart contraction)|go:"GO:0045823"(positive regulation of heart contraction)|go:"GO:0045989"(positive regulation of striated muscle contraction)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0051087"(chaperone binding)|go:"GO:0055085"(transmembrane transport)|go:"GO:0055119"(relaxation of cardiac muscle)|go:"GO:0060048"(cardiac muscle contraction)|go:"GO:0060081"(membrane hyperpolarization)|go:"GO:0071260"(cellular response to mechanical stimulus)|go:"GO:0071383"(cellular response to steroid hormone stimulus)|go:"GO:0086004"(regulation of cardiac muscle cell contraction)|go:"GO:0086009"(membrane repolarization)|go:"GO:1902600"(proton transmembrane transport)|go:"GO:1903416"(response to glycoside)|go:"GO:1990239"(steroid hormone binding)|go:"GO:1990573"(potassium ion import across plasma membrane)|interpro:IPR001757(ATPase, P-type, K/Mg/Cd/Cu/Zn/Na/Ca/Na/H-transporter)|interpro:IPR004014(ATPase, P-type cation-transporter, N-terminal)|interpro:IPR005775(ATPase, P-type cation exchange, alpha subunit, eukaryotic)|interpro:IPR006068(ATPase, P-type cation-transporter, C-terminal)|interpro:IPR008250(E1-E2 ATPase-associated region)|interpro:IPR018303|interpro:IPR023214|interpro:IPR023298|interpro:IPR023299|interpro:IPR036412|interpro:IPR044492|mint:P06685|rcsb pdb:1MO7|rcsb pdb:1MO8|reactome:R-RNO-5578775|reactome:R-RNO-936837	-	-	-	figure legend:st1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10116(rat-brain-cortex)|taxid:10116(Rattus norvegicus brain cortex)	-	2020/10/30	2020/10/30	rogid:DtE+ZXAZKdCMvUW5K+jXQ5bH07M10116	rogid:Chn3+kL+xhJd9yHk1JWVxqmhS4A10116	rigid:3wclwrjZRvafcOruQOYnegkn54c	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q5XIE8	uniprotkb:P62138	intact:EBI-15348306|ensembl:ENSRNOP00000023037	intact:EBI-357231|ensembl:ENSRNOP00000025282|uniprotkb:P08129|uniprotkb:P22802|uniprotkb:P20653	psi-mi:itm2b_rat(display_long)|uniprotkb:Itm2b(gene name)|psi-mi:Itm2b(display_short)|uniprotkb:Immature BRI2(gene name synonym)|uniprotkb:Transmembrane protein BRI(gene name synonym)	psi-mi:pp1a_rat(display_long)|uniprotkb:Ppp1ca(gene name)|psi-mi:Ppp1ca(display_short)|uniprotkb:Ppp1a(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Martins et al. (2018)	imex:IM-28469|pubmed:29476059	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26439741|imex:IM-28469-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSRNOG00000016271(gene)|ensembl:ENSRNOT00000023037(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001540"(amyloid-beta binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0010008"(endosome membrane)|go:"GO:0030660"(Golgi-associated vesicle membrane)|go:"GO:0031301"(integral component of organelle membrane)|go:"GO:0042985"(negative regulation of amyloid precursor protein biosynthetic process)|interpro:IPR007084(BRICHOS)|interpro:IPR040145|mint:Q5XIE8|refseq:NP_001006964.1|rgd:620727	ensembl:ENSRNOT00000025282(transcript)|go:"GO:0000164"(protein phosphatase type 1 complex)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0004721"(phosphoprotein phosphatase activity)|go:"GO:0004722"(protein serine/threonine phosphatase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005912"(adherens junction)|go:"GO:0005977"(glycogen metabolic process)|go:"GO:0005979"(regulation of glycogen biosynthetic process)|ensembl:ENSRNOG00000018708(gene)|go:"GO:0005981"(regulation of glycogen catabolic process)|go:"GO:0006470"(protein dephosphorylation)|go:"GO:0007049"(cell cycle)|go:"GO:0008157"(protein phosphatase 1 binding)|go:"GO:0010288"(response to lead ion)|go:"GO:0016311"(dephosphorylation)|go:"GO:0016791"(phosphatase activity)|go:"GO:0030324"(lung development)|go:"GO:0032922"(circadian regulation of gene expression)|go:"GO:0042587"(glycogen granule)|go:"GO:0042752"(regulation of circadian rhythm)|go:"GO:0043005"(neuron projection)|go:"GO:0043021"(ribonucleoprotein complex binding)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043153"(entrainment of circadian clock by photoperiod)|go:"GO:0043197"(dendritic spine)|go:"GO:0043204"(perikaryon)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0046872"(metal ion binding)|go:"GO:0048754"(branching morphogenesis of an epithelial tube)|go:"GO:0051301"(cell division)|go:"GO:0072357"(PTW/PP1 phosphatase complex)|go:"GO:0098641"(cadherin binding involved in cell-cell adhesion)|go:"GO:0098793"(presynapse)|go:"GO:0098794"(postsynapse)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0106306"|go:"GO:0106307"|go:"GO:2001241"(positive regulation of extrinsic apoptotic signaling pathway in absence of ligand)|interpro:IPR004843(Metallophosphoesterase)|interpro:IPR029052|interpro:IPR031675|interpro:IPR037979|mint:P62138|reactome:R-RNO-180024|interpro:IPR006186("Serine/threonine-specific protein phosphatase and bis(5-nucleosyl)-tetraphosphatase")|rgd:3375|refseq:NP_113715.1	-	-	-	figure legend:st1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10116(rat-brain-cortex)|taxid:10116(Rattus norvegicus brain cortex)	-	2020/10/30	2020/10/30	rogid:DtE+ZXAZKdCMvUW5K+jXQ5bH07M10116	rogid:IMypaKng+5AECbCd3N72pgzUlxQ10116	rigid:3wclwrjZRvafcOruQOYnegkn54c	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q5XIE8	uniprotkb:O08679	intact:EBI-15348306|ensembl:ENSRNOP00000023037	intact:EBI-15567525|ensembl:ENSRNOP00000028763	psi-mi:itm2b_rat(display_long)|uniprotkb:Itm2b(gene name)|psi-mi:Itm2b(display_short)|uniprotkb:Immature BRI2(gene name synonym)|uniprotkb:Transmembrane protein BRI(gene name synonym)	psi-mi:mark2_rat(display_long)|uniprotkb:Mark2(gene name)|psi-mi:Mark2(display_short)|uniprotkb:ELKL motif kinase 1(gene name synonym)|uniprotkb:MAP/microtubule affinity-regulating kinase 2(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Martins et al. (2018)	imex:IM-28469|pubmed:29476059	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26439741|imex:IM-28469-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSRNOG00000016271(gene)|ensembl:ENSRNOT00000023037(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001540"(amyloid-beta binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0010008"(endosome membrane)|go:"GO:0030660"(Golgi-associated vesicle membrane)|go:"GO:0031301"(integral component of organelle membrane)|go:"GO:0042985"(negative regulation of amyloid precursor protein biosynthetic process)|interpro:IPR007084(BRICHOS)|interpro:IPR040145|mint:Q5XIE8|refseq:NP_001006964.1|rgd:620727	ensembl:ENSRNOG00000021184(gene)|ensembl:ENSRNOT00000028763(transcript)|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0000287"(magnesium ion binding)|go:"GO:0001764"(neuron migration)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005884"(actin filament)|go:"GO:0005886"(plasma membrane)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0008289"(lipid binding)|go:"GO:0010976"(positive regulation of neuron projection development)|go:"GO:0016020"(membrane)|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0016328"(lateral plasma membrane)|go:"GO:0018105"(peptidyl-serine phosphorylation)|go:"GO:0030010"(establishment of cell polarity)|go:"GO:0030425"(dendrite)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0045180"(basal cortex)|go:"GO:0045197"(establishment or maintenance of epithelial cell apical/basal polarity)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0047485"(protein N-terminus binding)|go:"GO:0048156"(tau protein binding)|go:"GO:0050321"(tau-protein kinase activity)|go:"GO:0050770"(regulation of axonogenesis)|go:"GO:0051493"(regulation of cytoskeleton organization)|go:"GO:0061564"(axon development)|go:"GO:0070507"(regulation of microtubule cytoskeleton organization)|go:"GO:0071963"(establishment or maintenance of cell polarity regulating cell shape)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:1904526"(regulation of microtubule binding)|interpro:IPR000719(Protein kinase, core)|interpro:IPR001772(Kinase-associated KA1)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR015940(Ubiquitin-associated/translation elongation factor EF1B, N-terminal, eukaryote)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR028375|mint:O08679|go:"GO:0097427"(microtubule bundle)|rcsb pdb:1Y8G|rcsb pdb:1ZMU|rcsb pdb:1ZMV|rcsb pdb:1ZMW|rcsb pdb:2R0I|rcsb pdb:2WZJ|refseq:NP_067731.1|dip:DIP-29029N|rgd:708483	-	-	-	figure legend:st1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10116(rat-brain-cortex)|taxid:10116(Rattus norvegicus brain cortex)	-	2020/10/30	2020/10/30	rogid:DtE+ZXAZKdCMvUW5K+jXQ5bH07M10116	rogid:de9SgXVRPGVyoA3JKqItmnbhlPw10116	rigid:3wclwrjZRvafcOruQOYnegkn54c	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q5XIE8	uniprotkb:Q9JK11	intact:EBI-15348306|ensembl:ENSRNOP00000023037	intact:EBI-919972|uniprotkb:Q9JK10|uniprotkb:Q9R0D9|uniprotkb:Q9WUE9|uniprotkb:Q9WUF0	psi-mi:itm2b_rat(display_long)|uniprotkb:Itm2b(gene name)|psi-mi:Itm2b(display_short)|uniprotkb:Immature BRI2(gene name synonym)|uniprotkb:Transmembrane protein BRI(gene name synonym)	psi-mi:rtn4_rat(display_long)|uniprotkb:Rtn4(gene name)|psi-mi:Rtn4(display_short)|uniprotkb:Nogo(gene name synonym)|uniprotkb:Neurite outgrowth inhibitor(gene name synonym)|uniprotkb:Foocen(gene name synonym)|uniprotkb:Glut4 vesicle 20 kDa protein(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Martins et al. (2018)	imex:IM-28469|pubmed:29476059	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26439741|imex:IM-28469-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSRNOG00000016271(gene)|ensembl:ENSRNOT00000023037(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001540"(amyloid-beta binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0010008"(endosome membrane)|go:"GO:0030660"(Golgi-associated vesicle membrane)|go:"GO:0031301"(integral component of organelle membrane)|go:"GO:0042985"(negative regulation of amyloid precursor protein biosynthetic process)|interpro:IPR007084(BRICHOS)|interpro:IPR040145|mint:Q5XIE8|refseq:NP_001006964.1|rgd:620727	rgd:620989|refseq:NP_114019.1|refseq:XP_006251671.1|refseq:XP_006251670.2|mint:Q9JK11|refseq:XP_017454882.1|dip:DIP-37179N|go:"GO:0001825"(blastocyst formation)|go:"GO:0002523"(leukocyte migration involved in inflammatory response)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005886"(plasma membrane)|go:"GO:0007399"(nervous system development)|go:"GO:0007413"(axonal fasciculation)|go:"GO:0007568"(aging)|go:"GO:0010634"(positive regulation of epithelial cell migration)|go:"GO:0010977"(negative regulation of neuron projection development)|go:"GO:0014069"(postsynaptic density)|go:"GO:0014823"(response to activity)|go:"GO:0016021"(integral component of membrane)|go:"GO:0021553"(olfactory nerve development)|go:"GO:0021801"(cerebral cortex radial glia-guided migration)|go:"GO:0022009"(central nervous system vasculogenesis)|go:"GO:0030054"(cell junction)|go:"GO:0030176"(integral component of endoplasmic reticulum membrane)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0030517"(negative regulation of axon extension)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033601"(positive regulation of mammary gland epithelial cell proliferation)|go:"GO:0033603"(positive regulation of dopamine secretion)|go:"GO:0034165"(positive regulation of toll-like receptor 9 signaling pathway)|go:"GO:0035022"(positive regulation of Rac protein signal transduction)|go:"GO:0035441"(cell migration involved in vasculogenesis)|go:"GO:0042995"(cell projection)|go:"GO:0043005"(neuron projection)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043209"(myelin sheath)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045665"(negative regulation of neuron differentiation)|go:"GO:0045687"(positive regulation of glial cell differentiation)|go:"GO:0045766"(positive regulation of angiogenesis)|go:"GO:0048709"(oligodendrocyte differentiation)|go:"GO:0050771"(negative regulation of axonogenesis)|go:"GO:0050821"(protein stabilization)|go:"GO:0051292"(nuclear pore complex assembly)|go:"GO:0051897"(positive regulation of protein kinase B signaling)|go:"GO:0051930"(regulation of sensory perception of pain)|go:"GO:0051960"(regulation of nervous system development)|go:"GO:0060317"(cardiac epithelial to mesenchymal transition)|go:"GO:0060907"(positive regulation of macrophage cytokine production)|go:"GO:0061462"(protein localization to lysosome)|go:"GO:0070571"(negative regulation of neuron projection regeneration)|go:"GO:0071456"(cellular response to hypoxia)|go:"GO:0071782"(endoplasmic reticulum tubular network)|go:"GO:0071786"(endoplasmic reticulum tubular network organization)|go:"GO:0071787"(endoplasmic reticulum tubular network formation)|go:"GO:0090156"(cellular sphingolipid homeostasis)|go:"GO:0098826"(endoplasmic reticulum tubular network membrane)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099061"(integral component of postsynaptic density membrane)|go:"GO:0120078"(cell adhesion involved in sprouting angiogenesis)|go:"GO:1902430"(negative regulation of amyloid-beta formation)|go:"GO:1902624"(positive regulation of neutrophil migration)|go:"GO:1905523"(positive regulation of macrophage migration)|go:"GO:1905552"(positive regulation of protein localization to endoplasmic reticulum)|go:"GO:1905580"(positive regulation of ERBB3 signaling pathway)|go:"GO:1905653"(positive regulation of artery morphogenesis)|go:"GO:1990809"(endoplasmic reticulum tubular network membrane organization)|go:"GO:2000172"(regulation of branching morphogenesis of a nerve)|go:"GO:2000347"(positive regulation of hepatocyte proliferation)|go:"GO:2001213"(negative regulation of vasculogenesis)|interpro:IPR003388(Reticulon)|reactome:R-RNO-193634	-	-	-	figure legend:st1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10116(rat-brain-cortex)|taxid:10116(Rattus norvegicus brain cortex)	-	2020/10/30	2020/10/30	rogid:DtE+ZXAZKdCMvUW5K+jXQ5bH07M10116	rogid:CEWzvhKyKl/Cdz7MmociJDKwNPk10116	rigid:3wclwrjZRvafcOruQOYnegkn54c	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q5XIE8	uniprotkb:Q9JIR4	intact:EBI-15348306|ensembl:ENSRNOP00000023037	intact:EBI-3507436|uniprotkb:O35168	psi-mi:itm2b_rat(display_long)|uniprotkb:Itm2b(gene name)|psi-mi:Itm2b(display_short)|uniprotkb:Immature BRI2(gene name synonym)|uniprotkb:Transmembrane protein BRI(gene name synonym)	psi-mi:rims1_rat(display_long)|uniprotkb:Rims1(gene name)|psi-mi:Rims1(display_short)|uniprotkb:Rim1(gene name synonym)|uniprotkb:Rab-3-interacting molecule 1(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Martins et al. (2018)	imex:IM-28469|pubmed:29476059	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26439741|imex:IM-28469-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSRNOG00000016271(gene)|ensembl:ENSRNOT00000023037(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001540"(amyloid-beta binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0010008"(endosome membrane)|go:"GO:0030660"(Golgi-associated vesicle membrane)|go:"GO:0031301"(integral component of organelle membrane)|go:"GO:0042985"(negative regulation of amyloid precursor protein biosynthetic process)|interpro:IPR007084(BRICHOS)|interpro:IPR040145|mint:Q5XIE8|refseq:NP_001006964.1|rgd:620727	rgd:620000|refseq:NP_439894.1|go:"GO:0060291"(long-term synaptic potentiation)|go:"GO:0060478"(acrosomal vesicle exocytosis)|go:"GO:0061669"(spontaneous neurotransmitter secretion)|go:"GO:0065003"(protein-containing complex assembly)|go:"GO:0097151"(positive regulation of inhibitory postsynaptic potential)|go:"GO:0098831"(presynaptic active zone cytoplasmic component)|go:"GO:0098882"(structural constituent of presynaptic active zone)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0098982"(GABA-ergic synapse)|go:"GO:1903861"(positive regulation of dendrite extension)|go:"GO:2000300"(regulation of synaptic vesicle exocytosis)|go:"GO:2000463"(positive regulation of excitatory postsynaptic potential)|interpro:IPR000008(C2 calcium-dependent membrane targeting)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR010911(Rab-binding)|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|interpro:IPR017455(Zinc finger, FYVE-related)|interpro:IPR035892|interpro:IPR036034|interpro:IPR039032|interpro:IPR041282|rcsb pdb:1ZUB|rcsb pdb:2Q3X|reactome:R-RNO-181429|reactome:R-RNO-181430|reactome:R-RNO-210500|reactome:R-RNO-212676|reactome:R-RNO-264642|reactome:R-RNO-888590|go:"GO:0005886"(plasma membrane)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0007269"(neurotransmitter secretion)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010808"(positive regulation of synaptic vesicle priming)|go:"GO:0014069"(postsynaptic density)|go:"GO:0016081"(synaptic vesicle docking)|go:"GO:0016082"(synaptic vesicle priming)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030154"(cell differentiation)|go:"GO:0031267"(small GTPase binding)|go:"GO:0031632"(positive regulation of synaptic vesicle fusion to presynaptic active zone membrane)|go:"GO:0031982"(vesicle)|go:"GO:0042391"(regulation of membrane potential)|go:"GO:0042734"(presynaptic membrane)|go:"GO:0042995"(cell projection)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0045202"(synapse)|go:"GO:0046872"(metal ion binding)|go:"GO:0048167"(regulation of synaptic plasticity)|go:"GO:0048169"(regulation of long-term neuronal synaptic plasticity)|go:"GO:0048788"(cytoskeleton of presynaptic active zone)|go:"GO:0048791"(calcium ion-regulated exocytosis of neurotransmitter)|go:"GO:0050806"(positive regulation of synaptic transmission)|go:"GO:0060077"(inhibitory synapse)|mint:Q9JIR4|dip:DIP-41432N	-	-	-	figure legend:st1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10116(rat-brain-cortex)|taxid:10116(Rattus norvegicus brain cortex)	-	2020/10/30	2020/10/30	rogid:DtE+ZXAZKdCMvUW5K+jXQ5bH07M10116	rogid:Qk1J57peZ9ZCLtiLg1v5R4LAlF410116	rigid:3wclwrjZRvafcOruQOYnegkn54c	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q5XIE8	uniprotkb:Q63941	intact:EBI-15348306|ensembl:ENSRNOP00000023037	intact:EBI-26439206|ensembl:ENSRNOP00000010645	psi-mi:itm2b_rat(display_long)|uniprotkb:Itm2b(gene name)|psi-mi:Itm2b(display_short)|uniprotkb:Immature BRI2(gene name synonym)|uniprotkb:Transmembrane protein BRI(gene name synonym)	psi-mi:rab3b_rat(display_long)|uniprotkb:Rab3b(gene name)|psi-mi:Rab3b(display_short)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Martins et al. (2018)	imex:IM-28469|pubmed:29476059	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26439741|imex:IM-28469-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSRNOG00000016271(gene)|ensembl:ENSRNOT00000023037(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001540"(amyloid-beta binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0010008"(endosome membrane)|go:"GO:0030660"(Golgi-associated vesicle membrane)|go:"GO:0031301"(integral component of organelle membrane)|go:"GO:0042985"(negative regulation of amyloid precursor protein biosynthetic process)|interpro:IPR007084(BRICHOS)|interpro:IPR040145|mint:Q5XIE8|refseq:NP_001006964.1|rgd:620727	go:"GO:0018125"(peptidyl-cysteine methylation)|go:"GO:0019003"(GDP binding)|go:"GO:0019882"(antigen processing and presentation)|go:"GO:0030742"(GTP-dependent protein binding)|go:"GO:0031489"(myosin V binding)|go:"GO:0031982"(vesicle)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051586"(positive regulation of dopamine uptake involved in synaptic transmission)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0097494"(regulation of vesicle size)|go:"GO:0098691"(dopaminergic synapse)|go:"GO:0098693"(regulation of synaptic vesicle cycle)|go:"GO:0098993"(anchored component of synaptic vesicle membrane)|interpro:IPR001806(Ras GTPase)|interpro:IPR005225(Small GTP-binding protein)|interpro:IPR027417|go:"GO:0017157"(regulation of exocytosis)|interpro:IPR037872|mint:Q63941|reactome:R-RNO-8873719|ensembl:ENSRNOG00000008001(gene)|ensembl:ENSRNOT00000010645(transcript)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006904"(vesicle docking involved in exocytosis)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0009306"(protein secretion)|refseq:NP_112353.1|rgd:620922	-	-	-	figure legend:st1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10116(rat-brain-cortex)|taxid:10116(Rattus norvegicus brain cortex)	-	2020/10/30	2020/10/30	rogid:DtE+ZXAZKdCMvUW5K+jXQ5bH07M10116	rogid:EUhRe2V1G/DG6pExrhSibfBkLOo10116	rigid:3wclwrjZRvafcOruQOYnegkn54c	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q5XIE8	uniprotkb:P05712	intact:EBI-15348306|ensembl:ENSRNOP00000023037	intact:EBI-915929	psi-mi:itm2b_rat(display_long)|uniprotkb:Itm2b(gene name)|psi-mi:Itm2b(display_short)|uniprotkb:Immature BRI2(gene name synonym)|uniprotkb:Transmembrane protein BRI(gene name synonym)	psi-mi:rab2a_rat(display_long)|uniprotkb:Rab2a(gene name)|psi-mi:Rab2a(display_short)|uniprotkb:Rab2(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Martins et al. (2018)	imex:IM-28469|pubmed:29476059	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26439741|imex:IM-28469-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSRNOG00000016271(gene)|ensembl:ENSRNOT00000023037(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001540"(amyloid-beta binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0010008"(endosome membrane)|go:"GO:0030660"(Golgi-associated vesicle membrane)|go:"GO:0031301"(integral component of organelle membrane)|go:"GO:0042985"(negative regulation of amyloid precursor protein biosynthetic process)|interpro:IPR007084(BRICHOS)|interpro:IPR040145|mint:Q5XIE8|refseq:NP_001006964.1|rgd:620727	go:"GO:0000139"(Golgi membrane)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0007030"(Golgi organization)|go:"GO:0015031"(protein transport)|go:"GO:0016020"(membrane)|go:"GO:0016192"(vesicle-mediated transport)|go:"GO:0019003"(GDP binding)|go:"GO:0032482"(Rab protein signal transduction)|go:"GO:0033116"(endoplasmic reticulum-Golgi intermediate compartment membrane)|go:"GO:0042470"(melanosome)|go:"GO:0043025"(neuronal cell body)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0098993"(anchored component of synaptic vesicle membrane)|reactome:R-RNO-162658|reactome:R-RNO-8873719|rgd:68323|refseq:NP_113906.1|interpro:IPR005225(Small GTP-binding protein)|interpro:IPR001806(Ras GTPase)|interpro:IPR027417|mint:P05712	-	-	-	figure legend:st1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10116(rat-brain-cortex)|taxid:10116(Rattus norvegicus brain cortex)	-	2020/10/30	2020/10/30	rogid:DtE+ZXAZKdCMvUW5K+jXQ5bH07M10116	rogid:Tgp/mFQYzl3y51w6GcV+6dAeks010116	rigid:3wclwrjZRvafcOruQOYnegkn54c	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q5XIE8	uniprotkb:Q9QUH6	intact:EBI-15348306|ensembl:ENSRNOP00000023037	intact:EBI-2310349|uniprotkb:O88449|uniprotkb:Q9ESK6|uniprotkb:Q9ET81|uniprotkb:Q9QX02|uniprotkb:Q9QX06|uniprotkb:Q9QX12	psi-mi:itm2b_rat(display_long)|uniprotkb:Itm2b(gene name)|psi-mi:Itm2b(display_short)|uniprotkb:Immature BRI2(gene name synonym)|uniprotkb:Transmembrane protein BRI(gene name synonym)	psi-mi:sygp1_rat(display_long)|uniprotkb:Syngap1(gene name)|psi-mi:Syngap1(display_short)|uniprotkb:Synaptic Ras GTPase-activating protein 1(gene name synonym)|uniprotkb:p135 SynGAP(gene name synonym)|uniprotkb:Neuronal RasGAP(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Martins et al. (2018)	imex:IM-28469|pubmed:29476059	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26439741|imex:IM-28469-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSRNOG00000016271(gene)|ensembl:ENSRNOT00000023037(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001540"(amyloid-beta binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0010008"(endosome membrane)|go:"GO:0030660"(Golgi-associated vesicle membrane)|go:"GO:0031301"(integral component of organelle membrane)|go:"GO:0042985"(negative regulation of amyloid precursor protein biosynthetic process)|interpro:IPR007084(BRICHOS)|interpro:IPR040145|mint:Q5XIE8|refseq:NP_001006964.1|rgd:620727	rgd:621090|interpro:IPR000008(C2 calcium-dependent membrane targeting)|interpro:IPR021887|interpro:IPR001849(Pleckstrin-like)|interpro:IPR001936(Ras GTPase-activating protein)|interpro:IPR023152|interpro:IPR008936(Rho GTPase activation protein)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR037779|mint:Q9QUH6|interpro:IPR035892|interpro:IPR039360|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0007265"(Ras protein signal transduction)|go:"GO:0007389"(pattern specification process)|go:"GO:0008542"(visual learning)|go:"GO:0014069"(postsynaptic density)|go:"GO:0016020"(membrane)|go:"GO:0016358"(dendrite development)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0043087"(regulation of GTPase activity)|go:"GO:0043113"(receptor clustering)|go:"GO:0043198"(dendritic shaft)|go:"GO:0043408"(regulation of MAPK cascade)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0045202"(synapse)|go:"GO:0046580"(negative regulation of Ras protein signal transduction)|go:"GO:0048167"(regulation of synaptic plasticity)|go:"GO:0048169"(regulation of long-term neuronal synaptic plasticity)|go:"GO:0050771"(negative regulation of axonogenesis)|go:"GO:0050803"(regulation of synapse structure or activity)|go:"GO:0098880"(maintenance of postsynaptic specialization structure)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099092"(postsynaptic density, intracellular component)|rcsb pdb:3BXJ|reactome:R-RNO-5658442	-	-	-	figure legend:st1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10116(rat-brain-cortex)|taxid:10116(Rattus norvegicus brain cortex)	-	2020/10/30	2020/10/30	rogid:DtE+ZXAZKdCMvUW5K+jXQ5bH07M10116	rogid:GeVjX9zCfnB6li9EbUzVozittrw10116	rigid:3wclwrjZRvafcOruQOYnegkn54c	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q5XIE8	uniprotkb:F1M386	intact:EBI-15348306|ensembl:ENSRNOP00000023037	intact:EBI-26439125|ensembl:ENSRNOP00000037119|uniprotkb:D3ZD17	psi-mi:itm2b_rat(display_long)|uniprotkb:Itm2b(gene name)|psi-mi:Itm2b(display_short)|uniprotkb:Immature BRI2(gene name synonym)|uniprotkb:Transmembrane protein BRI(gene name synonym)	psi-mi:rpgf2_rat(display_long)|uniprotkb:Rapgef2(gene name)|psi-mi:Rapgef2(display_short)|uniprotkb:Pdzgef1(gene name synonym)|uniprotkb:Cyclic nucleotide ras GEF(gene name synonym)|uniprotkb:Neural RAP guanine nucleotide exchange protein(gene name synonym)|uniprotkb:PDZ domain-containing guanine nucleotide exchange factor 1(gene name synonym)|uniprotkb:RA-GEF-1(gene name synonym)|uniprotkb:Ras/Rap1-associating GEF-1(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Martins et al. (2018)	imex:IM-28469|pubmed:29476059	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26439741|imex:IM-28469-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSRNOG00000016271(gene)|ensembl:ENSRNOT00000023037(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001540"(amyloid-beta binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0010008"(endosome membrane)|go:"GO:0030660"(Golgi-associated vesicle membrane)|go:"GO:0031301"(integral component of organelle membrane)|go:"GO:0042985"(negative regulation of amyloid precursor protein biosynthetic process)|interpro:IPR007084(BRICHOS)|interpro:IPR040145|mint:Q5XIE8|refseq:NP_001006964.1|rgd:620727	ensembl:ENSRNOG00000021581(gene)|ensembl:ENSRNOT00000029340(transcript)|go:"GO:0001568"(blood vessel development)|go:"GO:0001764"(neuron migration)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005770"(late endosome)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005923"(bicellular tight junction)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0010976"(positive regulation of neuron projection development)|go:"GO:0016020"(membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0019901"(protein kinase binding)|go:"GO:0019933"(cAMP-mediated signaling)|go:"GO:0021591"(ventricular system development)|go:"GO:0021884"(forebrain neuron development)|go:"GO:0030033"(microvillus assembly)|go:"GO:0007218"(neuropeptide signaling pathway)|go:"GO:0030139"(endocytic vesicle)|go:"GO:0030165"(PDZ domain binding)|go:"GO:0030552"(cAMP binding)|go:"GO:0031175"(neuron projection development)|go:"GO:0031547"(brain-derived neurotrophic factor receptor signaling pathway)|go:"GO:0031697"(beta-1 adrenergic receptor binding)|go:"GO:0032092"(positive regulation of protein binding)|go:"GO:0032486"(Rap protein signal transduction)|go:"GO:0032991"(protein-containing complex)|go:"GO:0038180"(nerve growth factor signaling pathway)|go:"GO:0043005"(neuron projection)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043547"(positive regulation of GTPase activity)|go:"GO:0043950"(positive regulation of cAMP-mediated signaling)|go:"GO:0045202"(synapse)|go:"GO:0045860"(positive regulation of protein kinase activity)|go:"GO:0048022"(negative regulation of melanin biosynthetic process)|go:"GO:0048167"(regulation of synaptic plasticity)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0050699"(WW domain binding)|go:"GO:0050774"(negative regulation of dendrite morphogenesis)|go:"GO:0061028"(establishment of endothelial barrier)|go:"GO:0070300"(phosphatidic acid binding)|go:"GO:0070374"(positive regulation of ERK1 and ERK2 cascade)|go:"GO:0071320"(cellular response to cAMP)|go:"GO:0071321"(cellular response to cGMP)|go:"GO:0071880"(adenylate cyclase-activating adrenergic receptor signaling pathway)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0090557"(establishment of endothelial intestinal barrier)|go:"GO:1901888"(regulation of cell junction assembly)|go:"GO:1990090"(cellular response to nerve growth factor stimulus)|go:"GO:2000481"(positive regulation of cAMP-dependent protein kinase activity)|go:"GO:2000670"(positive regulation of dendritic cell apoptotic process)|go:"GO:2001214"(positive regulation of vasculogenesis)|go:"GO:2001224"(positive regulation of neuron migration)|interpro:IPR000159(Ras-association)|interpro:IPR000595(Cyclic nucleotide-binding)|interpro:IPR000651(Guanine nucleotide exchange factor for Ras-like GTPases, N-terminal)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR001895(Guanine-nucleotide dissociation stimulator CDC25)|interpro:IPR008937(Ras guanine nucleotide exchange factor)|interpro:IPR018490|interpro:IPR023578|interpro:IPR029071|interpro:IPR030739|interpro:IPR036034|mint:F1M386|reactome:R-RNO-5673001|interpro:IPR014710(RmlC-like jelly roll fold)|refseq:XP_006232574.1|rgd:1306434|refseq:NP_001101154.1	-	-	-	figure legend:st1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10116(rat-brain-cortex)|taxid:10116(Rattus norvegicus brain cortex)	-	2020/10/30	2020/10/30	rogid:DtE+ZXAZKdCMvUW5K+jXQ5bH07M10116	rogid:rbqdqDAICexG8tJryScoCC2ElwA10116	rigid:3wclwrjZRvafcOruQOYnegkn54c	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q5XIE8	uniprotkb:Q6MG48	intact:EBI-15348306|ensembl:ENSRNOP00000023037	intact:EBI-22255416|ensembl:ENSRNOP00000001133	psi-mi:itm2b_rat(display_long)|uniprotkb:Itm2b(gene name)|psi-mi:Itm2b(display_short)|uniprotkb:Immature BRI2(gene name synonym)|uniprotkb:Transmembrane protein BRI(gene name synonym)	psi-mi:prc2a_rat(display_long)|uniprotkb:HLA-B-associated transcript 2(gene name synonym)|uniprotkb:Proline-rich and coiled-coil-containing protein 2A(gene name synonym)|uniprotkb:Prrc2a(gene name)|psi-mi:Prrc2a(display_short)|uniprotkb:Bat2(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Martins et al. (2018)	imex:IM-28469|pubmed:29476059	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26439741|imex:IM-28469-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSRNOG00000016271(gene)|ensembl:ENSRNOT00000023037(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001540"(amyloid-beta binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0010008"(endosome membrane)|go:"GO:0030660"(Golgi-associated vesicle membrane)|go:"GO:0031301"(integral component of organelle membrane)|go:"GO:0042985"(negative regulation of amyloid precursor protein biosynthetic process)|interpro:IPR007084(BRICHOS)|interpro:IPR040145|mint:Q5XIE8|refseq:NP_001006964.1|rgd:620727	interpro:IPR033184|mint:Q6MG48|ensembl:ENSRNOG00000000852(gene)|ensembl:ENSRNOT00000001133(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0030154"(cell differentiation)|interpro:IPR009738(BAT2, N-terminal)|rgd:1303025|refseq:NP_997627.1|refseq:XP_006256114.1	-	-	-	figure legend:st1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10116(rat-brain-cortex)|taxid:10116(Rattus norvegicus brain cortex)	-	2020/10/30	2020/10/30	rogid:DtE+ZXAZKdCMvUW5K+jXQ5bH07M10116	rogid:L0nUv9Vo7Y/Saz9CLiO2h3CwNDc10116	rigid:3wclwrjZRvafcOruQOYnegkn54c	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q5XIE8	uniprotkb:Q9JKS6	intact:EBI-15348306|ensembl:ENSRNOP00000023037	intact:EBI-2271602|uniprotkb:Q9JLT1	psi-mi:itm2b_rat(display_long)|uniprotkb:Itm2b(gene name)|psi-mi:Itm2b(display_short)|uniprotkb:Immature BRI2(gene name synonym)|uniprotkb:Transmembrane protein BRI(gene name synonym)	psi-mi:pclo_rat(display_long)|uniprotkb:Pclo(gene name)|psi-mi:Pclo(display_short)|uniprotkb:Aczonin(gene name synonym)|uniprotkb:Multidomain presynaptic cytomatrix protein(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Martins et al. (2018)	imex:IM-28469|pubmed:29476059	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26439741|imex:IM-28469-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSRNOG00000016271(gene)|ensembl:ENSRNOT00000023037(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001540"(amyloid-beta binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0010008"(endosome membrane)|go:"GO:0030660"(Golgi-associated vesicle membrane)|go:"GO:0031301"(integral component of organelle membrane)|go:"GO:0042985"(negative regulation of amyloid precursor protein biosynthetic process)|interpro:IPR007084(BRICHOS)|interpro:IPR040145|mint:Q5XIE8|refseq:NP_001006964.1|rgd:620727	rgd:69406|refseq:NP_001104267.1|refseq:NP_064483.1|interpro:IPR000008(C2 calcium-dependent membrane targeting)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|interpro:IPR008899(Zinc finger, piccolo-type)|interpro:IPR042720|interpro:IPR030629|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|mint:Q9JKS6|interpro:IPR035892|interpro:IPR036034|go:"GO:0001222"(transcription corepressor binding)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005522"(profilin binding)|go:"GO:0005544"(calcium-dependent phospholipid binding)|go:"GO:0005798"(Golgi-associated vesicle)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0007010"(cytoskeleton organization)|go:"GO:0014069"(postsynaptic density)|go:"GO:0016080"(synaptic vesicle targeting)|go:"GO:0017157"(regulation of exocytosis)|go:"GO:0019933"(cAMP-mediated signaling)|go:"GO:0030073"(insulin secretion)|go:"GO:0030133"(transport vesicle)|go:"GO:0030424"(axon)|go:"GO:0030425"(dendrite)|go:"GO:0030426"(growth cone)|go:"GO:0031594"(neuromuscular junction)|go:"GO:0035418"(protein localization to synapse)|go:"GO:0043005"(neuron projection)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043195"(terminal bouton)|go:"GO:0044316"(cone cell pedicle)|go:"GO:0044317"(rod spherule)|go:"GO:0045202"(synapse)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0048786"(presynaptic active zone)|go:"GO:0048788"(cytoskeleton of presynaptic active zone)|go:"GO:0050808"(synapse organization)|go:"GO:0051036"(regulation of endosome size)|go:"GO:0060077"(inhibitory synapse)|go:"GO:0097091"(synaptic vesicle clustering)|go:"GO:0097470"(ribbon synapse)|go:"GO:0098688"(parallel fiber to Purkinje cell synapse)|go:"GO:0098815"(modulation of excitatory postsynaptic potential)|go:"GO:0098831"(presynaptic active zone cytoplasmic component)|go:"GO:0098882"(structural constituent of presynaptic active zone)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0098982"(GABA-ergic synapse)|go:"GO:0099526"(presynapse to nucleus signaling pathway)|go:"GO:1903423"(positive regulation of synaptic vesicle recycling)|go:"GO:1904071"(presynaptic active zone assembly)|go:"GO:1904666"(regulation of ubiquitin protein ligase activity)|rcsb pdb:1RH8	-	-	-	figure legend:st1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10116(rat-brain-cortex)|taxid:10116(Rattus norvegicus brain cortex)	-	2020/10/30	2020/10/30	rogid:DtE+ZXAZKdCMvUW5K+jXQ5bH07M10116	rogid:OnCRNzqU4rxi3dXGZHJ6mRcuLKs10116	rigid:3wclwrjZRvafcOruQOYnegkn54c	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q5XIE8	uniprotkb:O88767	intact:EBI-15348306|ensembl:ENSRNOP00000023037	intact:EBI-915704|ensembl:ENSRNOP00000024711|ensembl:ENSRNOP00000072068	psi-mi:itm2b_rat(display_long)|uniprotkb:Itm2b(gene name)|psi-mi:Itm2b(display_short)|uniprotkb:Immature BRI2(gene name synonym)|uniprotkb:Transmembrane protein BRI(gene name synonym)	psi-mi:park7_rat(display_long)|uniprotkb:Contraception-associated protein 1(gene name synonym)|uniprotkb:Fertility protein SP22(gene name synonym)|uniprotkb:Maillard deglycase(gene name synonym)|uniprotkb:Parkinsonism-associated deglycase(gene name synonym)|uniprotkb:Protein DJ-1(gene name synonym)|uniprotkb:Protein/nucleic acid deglycase DJ-1(gene name synonym)|uniprotkb:Park7(gene name)|psi-mi:Park7(display_short)|uniprotkb:Cap1(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Martins et al. (2018)	imex:IM-28469|pubmed:29476059	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26439741|imex:IM-28469-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSRNOG00000016271(gene)|ensembl:ENSRNOT00000023037(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001540"(amyloid-beta binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0010008"(endosome membrane)|go:"GO:0030660"(Golgi-associated vesicle membrane)|go:"GO:0031301"(integral component of organelle membrane)|go:"GO:0042985"(negative regulation of amyloid precursor protein biosynthetic process)|interpro:IPR007084(BRICHOS)|interpro:IPR040145|mint:Q5XIE8|refseq:NP_001006964.1|rgd:620727	rgd:621808|refseq:NP_476484.1|ensembl:ENSRNOG00000018289(gene)|ensembl:ENSRNOT00000024711(transcript)|ensembl:ENSRNOT00000087402(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0001933"(negative regulation of protein phosphorylation)|go:"GO:0001963"(synaptic transmission, dopaminergic)|go:"GO:0002866"(positive regulation of acute inflammatory response to antigenic stimulus)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0003729"(mRNA binding)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005507"(copper ion binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005758"(mitochondrial intermembrane space)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006281"(DNA repair)|go:"GO:0006469"(negative regulation of protein kinase activity)|go:"GO:0006517"(protein deglycosylation)|go:"GO:0006914"(autophagy)|go:"GO:0006954"(inflammatory response)|go:"GO:0006979"(response to oxidative stress)|go:"GO:0007005"(mitochondrion organization)|go:"GO:0007283"(spermatogenesis)|go:"GO:0007338"(single fertilization)|go:"GO:0007568"(aging)|go:"GO:0008134"(transcription factor binding)|go:"GO:0008233"(peptidase activity)|go:"GO:0008344"(adult locomotory behavior)|go:"GO:0009438"(methylglyoxal metabolic process)|go:"GO:0009566"(fertilization)|go:"GO:0010273"(detoxification of copper ion)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0016532"(superoxide dismutase copper chaperone activity)|go:"GO:0016570"(histone modification)|go:"GO:0016605"(PML body)|go:"GO:0016684"(oxidoreductase activity, acting on peroxide as acceptor)|go:"GO:0019249"(lactate biosynthetic process)|go:"GO:0019826"(oxygen sensor activity)|go:"GO:0019899"(enzyme binding)|go:"GO:0019900"(kinase binding)|go:"GO:0019955"(cytokine binding)|go:"GO:0030073"(insulin secretion)|refseq:NP_001264179.1|refseq:NP_001264180.1|refseq:NP_001264181.1|refseq:NP_001264182.1|go:"GO:0030424"(axon)|go:"GO:0031334"(positive regulation of protein-containing complex assembly)|go:"GO:0031397"(negative regulation of protein ubiquitination)|go:"GO:0032091"(negative regulation of protein binding)|go:"GO:0032435"(negative regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0032757"(positive regulation of interleukin-8 production)|go:"GO:0033138"(positive regulation of peptidyl-serine phosphorylation)|go:"GO:0033182"(regulation of histone ubiquitination)|go:"GO:0033234"(negative regulation of protein sumoylation)|go:"GO:0033864"("positive regulation of NAD(P)H oxidase activity")|go:"GO:0034599"(cellular response to oxidative stress)|go:"GO:0034614"(cellular response to reactive oxygen species)|go:"GO:0035065"(regulation of histone acetylation)|go:"GO:0036470"(tyrosine 3-monooxygenase activator activity)|go:"GO:0036471"(cellular response to glyoxal)|go:"GO:0036478"(L-dopa decarboxylase activator activity)|go:"GO:0036524"(protein deglycase activity)|go:"GO:0036526"(peptidyl-cysteine deglycation)|go:"GO:0036527"(peptidyl-arginine deglycation)|go:"GO:0036528"(peptidyl-lysine deglycation)|go:"GO:0036529"(protein deglycation, glyoxal removal)|go:"GO:0036530"(protein deglycation, methylglyoxal removal)|go:"GO:0036531"(glutathione deglycation)|go:"GO:0042177"(negative regulation of protein catabolic process)|go:"GO:0042493"|go:"GO:0042542"(response to hydrogen peroxide)|go:"GO:0042593"(glucose homeostasis)|go:"GO:0042743"(hydrogen peroxide metabolic process)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043005"(neuron projection)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043523"(regulation of neuron apoptotic process)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0044297"(cell body)|go:"GO:0044388"(small protein activating enzyme binding)|go:"GO:0044390"(ubiquitin-like protein conjugating enzyme binding)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045121"(membrane raft)|go:"GO:0045340"(mercury ion binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046295"(glycolate biosynthetic process)|go:"GO:0046826"(negative regulation of protein export from nucleus)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0050681"(androgen receptor binding)|go:"GO:0050727"(regulation of inflammatory response)|go:"GO:0050787"(detoxification of mercury ion)|go:"GO:0050821"(protein stabilization)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0051444"(negative regulation of ubiquitin-protein transferase activity)|go:"GO:0051583"(dopamine uptake involved in synaptic transmission)|go:"GO:0051881"(regulation of mitochondrial membrane potential)|go:"GO:0051899"(membrane depolarization)|go:"GO:0051920"(peroxiredoxin activity)|go:"GO:0060081"(membrane hyperpolarization)|go:"GO:0060135"(maternal process involved in female pregnancy)|go:"GO:0060548"(negative regulation of cell death)|go:"GO:0060765"(regulation of androgen receptor signaling pathway)|go:"GO:0061727"(methylglyoxal catabolic process to lactate)|go:"GO:0061827"(sperm head)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070301"(cellular response to hydrogen peroxide)|go:"GO:0070994"(detection of oxidative stress)|go:"GO:0071222"(cellular response to lipopolysaccharide)|go:"GO:0097110"(scaffold protein binding)|go:"GO:0098793"(presynapse)|go:"GO:0106044"(guanine deglycation)|go:"GO:0106045"(guanine deglycation, methylglyoxal removal)|go:"GO:0106046"(guanine deglycation, glyoxal removal)|go:"GO:0110095"(cellular detoxification of aldehyde)|go:"GO:0140041"(cellular detoxification of methylglyoxal)|go:"GO:0140297"(DNA-binding transcription factor binding)|go:"GO:1900182"(positive regulation of protein localization to nucleus)|go:"GO:1901215"(negative regulation of neuron death)|go:"GO:1901671"(positive regulation of superoxide dismutase activity)|go:"GO:1901984"(negative regulation of protein acetylation)|go:"GO:1902177"(positive regulation of oxidative stress-induced intrinsic apoptotic signaling pathway)|go:"GO:1902236"(negative regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway)|go:"GO:1902958"(positive regulation of mitochondrial electron transport, NADH to ubiquinone)|go:"GO:1903094"(negative regulation of protein K48-linked deubiquitination)|go:"GO:1903122"(negative regulation of TRAIL-activated apoptotic signaling pathway)|go:"GO:1903135"(cupric ion binding)|go:"GO:1903136"(cuprous ion binding)|go:"GO:1903168"(positive regulation of pyrroline-5-carboxylate reductase activity)|go:"GO:1903178"(positive regulation of tyrosine 3-monooxygenase activity)|go:"GO:1903181"(positive regulation of dopamine biosynthetic process)|go:"GO:1903189"(glyoxal metabolic process)|go:"GO:1903197"(positive regulation of L-dopa biosynthetic process)|go:"GO:1903200"(positive regulation of L-dopa decarboxylase activity)|go:"GO:1903202"(negative regulation of oxidative stress-induced cell death)|go:"GO:1903204"(negative regulation of oxidative stress-induced neuron death)|go:"GO:1903206"(negative regulation of hydrogen peroxide-induced cell death)|go:"GO:1903208"(negative regulation of hydrogen peroxide-induced neuron death)|go:"GO:1903377"(negative regulation of oxidative stress-induced neuron intrinsic apoptotic signaling pathway)|go:"GO:1903384"(negative regulation of hydrogen peroxide-induced neuron intrinsic apoptotic signaling pathway)|go:"GO:1903427"(negative regulation of reactive oxygen species biosynthetic process)|go:"GO:1903428"(positive regulation of reactive oxygen species biosynthetic process)|go:"GO:1904782"(negative regulation of NMDA glutamate receptor activity)|go:"GO:1905259"(negative regulation of nitrosative stress-induced intrinsic apoptotic signaling pathway)|go:"GO:1905516"(positive regulation of fertilization)|go:"GO:1990381"(ubiquitin-specific protease binding)|go:"GO:1990422"("glyoxalase (glycolic acid-forming) activity")|go:"GO:2000157"(negative regulation of ubiquitin-specific protease activity)|go:"GO:2000277"(positive regulation of oxidative phosphorylation uncoupler activity)|go:"GO:2000679"(positive regulation of transcription regulatory region DNA binding)|go:"GO:2000825"(positive regulation of androgen receptor activity)|go:"GO:2001237"(negative regulation of extrinsic apoptotic signaling pathway)|go:"GO:2001268"(negative regulation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway)|interpro:IPR002818(ThiJ/PfpI)|interpro:IPR006287(DJ-1)|interpro:IPR029062|mint:O88767|reactome:R-RNO-3899300|reactome:R-RNO-9646399	-	-	-	figure legend:st1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10116(rat-brain-cortex)|taxid:10116(Rattus norvegicus brain cortex)	-	2020/10/30	2020/10/30	rogid:DtE+ZXAZKdCMvUW5K+jXQ5bH07M10116	rogid:Mbujzu7VP6rVyCAUKu78xXo4nXM10116	rigid:3wclwrjZRvafcOruQOYnegkn54c	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q5XIE8	uniprotkb:Q6AYD3	intact:EBI-15348306|ensembl:ENSRNOP00000023037	intact:EBI-1638420|ensembl:ENSRNOP00000006578	psi-mi:itm2b_rat(display_long)|uniprotkb:Itm2b(gene name)|psi-mi:Itm2b(display_short)|uniprotkb:Immature BRI2(gene name synonym)|uniprotkb:Transmembrane protein BRI(gene name synonym)	psi-mi:pa2g4_rat(display_long)|uniprotkb:Pa2g4(gene name)|psi-mi:Pa2g4(display_short)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Martins et al. (2018)	imex:IM-28469|pubmed:29476059	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26439741|imex:IM-28469-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSRNOG00000016271(gene)|ensembl:ENSRNOT00000023037(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001540"(amyloid-beta binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0010008"(endosome membrane)|go:"GO:0030660"(Golgi-associated vesicle membrane)|go:"GO:0031301"(integral component of organelle membrane)|go:"GO:0042985"(negative regulation of amyloid precursor protein biosynthetic process)|interpro:IPR007084(BRICHOS)|interpro:IPR040145|mint:Q5XIE8|refseq:NP_001006964.1|rgd:620727	rgd:1302994|refseq:NP_001004206.1|ensembl:ENSRNOG00000004904(gene)|ensembl:ENSRNOT00000006578(transcript)|go:"GO:0003676"(nucleic acid binding)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006364"(rRNA processing)|go:"GO:0006417"(regulation of translation)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0045597"(positive regulation of cell differentiation)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|interpro:IPR000994(Peptidase M24, catalytic core)|interpro:IPR004545(Proliferation-associated protein 1)|interpro:IPR018349|interpro:IPR036005|interpro:IPR036388|interpro:IPR036390|mint:Q6AYD3|reactome:R-RNO-6798695	-	-	-	figure legend:st1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10116(rat-brain-cortex)|taxid:10116(Rattus norvegicus brain cortex)	-	2020/10/30	2020/10/30	rogid:DtE+ZXAZKdCMvUW5K+jXQ5bH07M10116	rogid:T1HDP9hIDcT9tebsZBZRFVHC6kk10116	rigid:3wclwrjZRvafcOruQOYnegkn54c	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q5XIE8	uniprotkb:P62963	intact:EBI-15348306|ensembl:ENSRNOP00000023037	intact:EBI-916295|uniprotkb:P10924|ensembl:ENSRNOP00000005370	psi-mi:itm2b_rat(display_long)|uniprotkb:Itm2b(gene name)|psi-mi:Itm2b(display_short)|uniprotkb:Immature BRI2(gene name synonym)|uniprotkb:Transmembrane protein BRI(gene name synonym)	psi-mi:prof1_rat(display_long)|uniprotkb:Pfn1(gene name)|psi-mi:Pfn1(display_short)|uniprotkb:Profilin I(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Martins et al. (2018)	imex:IM-28469|pubmed:29476059	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26439741|imex:IM-28469-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSRNOG00000016271(gene)|ensembl:ENSRNOT00000023037(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001540"(amyloid-beta binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0010008"(endosome membrane)|go:"GO:0030660"(Golgi-associated vesicle membrane)|go:"GO:0031301"(integral component of organelle membrane)|go:"GO:0042985"(negative regulation of amyloid precursor protein biosynthetic process)|interpro:IPR007084(BRICHOS)|interpro:IPR040145|mint:Q5XIE8|refseq:NP_001006964.1|rgd:620727	refseq:NP_071956.2|go:"GO:0032781"(positive regulation of ATP-dependent activity)|go:"GO:0043005"(neuron projection)|go:"GO:0045202"(synapse)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0050434"(positive regulation of viral transcription)|go:"GO:0050821"(protein stabilization)|go:"GO:0051054"(positive regulation of DNA metabolic process)|go:"GO:0051496"(positive regulation of stress fiber assembly)|go:"GO:0051497"(negative regulation of stress fiber assembly)|go:"GO:0060074"(synapse maturation)|go:"GO:0070064"(proline-rich region binding)|go:"GO:0071363"(cellular response to growth factor stimulus)|go:"GO:0098685"(Schaffer collateral - CA1 synapse)|go:"GO:0098688"(parallel fiber to Purkinje cell synapse)|go:"GO:0098793"(presynapse)|go:"GO:0098794"(postsynapse)|go:"GO:0098885"(modification of postsynaptic actin cytoskeleton)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:1900029"(positive regulation of ruffle assembly)|interpro:IPR005454(Profilin, Mammalian)|interpro:IPR005455(Profilin, plant)|interpro:IPR027310|interpro:IPR029892|interpro:IPR036140|ensembl:ENSRNOG00000003975(gene)|ensembl:ENSRNOT00000005370(transcript)|go:"GO:0000774"(adenyl-nucleotide exchange factor activity)|go:"GO:0001784"(phosphotyrosine residue binding)|go:"GO:0001843"(neural tube closure)|go:"GO:0003779"(actin binding)|go:"GO:0003785"(actin monomer binding)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005546"(phosphatidylinositol-4,5-bisphosphate binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005938"(cell cortex)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0008154"(actin polymerization or depolymerization)|go:"GO:0010033"(response to organic substance)|go:"GO:0010634"(positive regulation of epithelial cell migration)|go:"GO:0030833"(regulation of actin filament polymerization)|go:"GO:0030837"(negative regulation of actin filament polymerization)|go:"GO:0030838"(positive regulation of actin filament polymerization)|go:"GO:0031267"(small GTPase binding)|go:"GO:0032232"(negative regulation of actin filament bundle assembly)|go:"GO:0032233"(positive regulation of actin filament bundle assembly)|mint:P62963|reactome:R-RNO-4086400|reactome:R-RNO-5663220|rgd:621825	-	-	-	figure legend:st1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10116(rat-brain-cortex)|taxid:10116(Rattus norvegicus brain cortex)	-	2020/10/30	2020/10/30	rogid:DtE+ZXAZKdCMvUW5K+jXQ5bH07M10116	rogid:nzOTw5XdywGrh+fA9AInGIexyGk10116	rigid:3wclwrjZRvafcOruQOYnegkn54c	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q5XIE8	uniprotkb:P0CG51	intact:EBI-15348306|ensembl:ENSRNOP00000023037	intact:EBI-26438955|uniprotkb:P02248|uniprotkb:P02249|uniprotkb:P02250|uniprotkb:P62989|uniprotkb:Q29120|uniprotkb:Q63446|uniprotkb:Q91887|uniprotkb:Q91888	psi-mi:itm2b_rat(display_long)|uniprotkb:Itm2b(gene name)|psi-mi:Itm2b(display_short)|uniprotkb:Immature BRI2(gene name synonym)|uniprotkb:Transmembrane protein BRI(gene name synonym)	psi-mi:ubb_rat(display_long)|uniprotkb:Ubb(gene name)|psi-mi:Ubb(display_short)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Martins et al. (2018)	imex:IM-28469|pubmed:29476059	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26439741|imex:IM-28469-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSRNOG00000016271(gene)|ensembl:ENSRNOT00000023037(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001540"(amyloid-beta binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0010008"(endosome membrane)|go:"GO:0030660"(Golgi-associated vesicle membrane)|go:"GO:0031301"(integral component of organelle membrane)|go:"GO:0042985"(negative regulation of amyloid precursor protein biosynthetic process)|interpro:IPR007084(BRICHOS)|interpro:IPR040145|mint:Q5XIE8|refseq:NP_001006964.1|rgd:620727	reactome:R-RNO-8863795|reactome:R-RNO-8866652|reactome:R-RNO-8866654|reactome:R-RNO-8932339|reactome:R-RNO-8939236|reactome:R-RNO-8941858|reactome:R-RNO-8948747|reactome:R-RNO-8948751|reactome:R-RNO-8951664|reactome:R-RNO-901032|reactome:R-RNO-9013507|reactome:R-RNO-9020702|reactome:R-RNO-9033241|reactome:R-RNO-912631|reactome:R-RNO-917729|reactome:R-RNO-917937|reactome:R-RNO-937042|reactome:R-RNO-937072|reactome:R-RNO-9645460|reactome:R-RNO-9646399|reactome:R-RNO-9648002|reactome:R-RNO-9664873|reactome:R-RNO-9705462|reactome:R-RNO-9706369|reactome:R-RNO-975163|reactome:R-RNO-983168|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0007141"(male meiosis I)|go:"GO:0007144"(female meiosis I)|go:"GO:0008584"(male gonad development)|go:"GO:0008585"(female gonad development)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0019941"(modification-dependent protein catabolic process)|go:"GO:0021888"(hypothalamus gonadotrophin-releasing hormone neuron development)|go:"GO:0031386"(protein tag)|go:"GO:0031398"(positive regulation of protein ubiquitination)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0043005"(neuron projection)|go:"GO:0043025"(neuronal cell body)|go:"GO:0047497"(mitochondrion transport along microtubule)|go:"GO:0048812"(neuron projection morphogenesis)|go:"GO:0051881"(regulation of mitochondrial membrane potential)|go:"GO:0060612"(adipose tissue development)|go:"GO:0060613"(fat pad development)|go:"GO:0061136"(regulation of proteasomal protein catabolic process)|go:"GO:0072520"(seminiferous tubule development)|go:"GO:0097009"(energy homeostasis)|go:"GO:1901214"(regulation of neuron death)|go:"GO:1902255"(positive regulation of intrinsic apoptotic signaling pathway by p53 class mediator)|go:"GO:1902527"(positive regulation of protein monoubiquitination)|reactome:R-RNO-110312|reactome:R-RNO-110314|reactome:R-RNO-110320|reactome:R-RNO-1169091|reactome:R-RNO-1234176|reactome:R-RNO-1253288|reactome:R-RNO-1295596|reactome:R-RNO-1358803|reactome:R-RNO-168638|reactome:R-RNO-174048|reactome:R-RNO-174084|reactome:R-RNO-174154|reactome:R-RNO-174178|reactome:R-RNO-174184|reactome:R-RNO-179409|reactome:R-RNO-182971|reactome:R-RNO-187577|reactome:R-RNO-195253|reactome:R-RNO-201681|reactome:R-RNO-205043|reactome:R-RNO-209543|reactome:R-RNO-209560|reactome:R-RNO-2122948|reactome:R-RNO-2173788|reactome:R-RNO-2173791|reactome:R-RNO-2173795|reactome:R-RNO-2173796|reactome:R-RNO-2467813|reactome:R-RNO-2559580|reactome:R-RNO-2559582|reactome:R-RNO-2559585|reactome:R-RNO-2565942|reactome:R-RNO-2672351|reactome:R-RNO-3134975|reactome:R-RNO-349425|reactome:R-RNO-3769402|reactome:R-RNO-382556|reactome:R-RNO-445989|reactome:R-RNO-450302|reactome:R-RNO-450321|reactome:R-RNO-450408|reactome:R-RNO-4608870|reactome:R-RNO-4641257|reactome:R-RNO-4641258|reactome:R-RNO-4641263|reactome:R-RNO-532668|reactome:R-RNO-5357905|reactome:R-RNO-5357956|reactome:R-RNO-5358346|reactome:R-RNO-5607761|reactome:R-RNO-5610780|reactome:R-RNO-5610785|reactome:R-RNO-5632684|reactome:R-RNO-5654726|reactome:R-RNO-5654727|reactome:R-RNO-5654732|reactome:R-RNO-5654733|reactome:R-RNO-5655862|reactome:R-RNO-5656121|reactome:R-RNO-5656169|reactome:R-RNO-5658442|reactome:R-RNO-5668541|reactome:R-RNO-5675221|reactome:R-RNO-5675482|reactome:R-RNO-5676590|reactome:R-RNO-5685942|reactome:R-RNO-5687128|reactome:R-RNO-5689603|reactome:R-RNO-5689877|reactome:R-RNO-5689880|reactome:R-RNO-5689896|reactome:R-RNO-5689901|reactome:R-RNO-5693565|reactome:R-RNO-5696394|reactome:R-RNO-5696395|reactome:R-RNO-5696397|reactome:R-RNO-5696400|reactome:R-RNO-6781823|reactome:R-RNO-6782135|reactome:R-RNO-6782210|reactome:R-RNO-6783310|reactome:R-RNO-6804756|reactome:R-RNO-6804757|reactome:R-RNO-6804760|reactome:R-RNO-6807004|reactome:R-RNO-68827|reactome:R-RNO-68949|reactome:R-RNO-69017|reactome:R-RNO-69231|reactome:R-RNO-69481|reactome:R-RNO-69541|reactome:R-RNO-69601|reactome:R-RNO-75815|reactome:R-RNO-8849469|reactome:R-RNO-8852276|reactome:R-RNO-8854050|reactome:R-RNO-8856825|reactome:R-RNO-8856828|mint:P0CG51|interpro:IPR000626(Ubiquitin)|interpro:IPR029071|interpro:IPR019954|interpro:IPR019956|rgd:621562	-	-	-	figure legend:st1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10116(rat-brain-cortex)|taxid:10116(Rattus norvegicus brain cortex)	-	2020/10/30	2020/10/30	rogid:DtE+ZXAZKdCMvUW5K+jXQ5bH07M10116	rogid:Rx+/zmzxbnmSyVdMSIgp6JvjLzs10116	rigid:3wclwrjZRvafcOruQOYnegkn54c	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q5XIE8	uniprotkb:P11506	intact:EBI-15348306|ensembl:ENSRNOP00000023037	intact:EBI-1174554|uniprotkb:Q63443	psi-mi:itm2b_rat(display_long)|uniprotkb:Itm2b(gene name)|psi-mi:Itm2b(display_short)|uniprotkb:Immature BRI2(gene name synonym)|uniprotkb:Transmembrane protein BRI(gene name synonym)	psi-mi:at2b2_rat(display_long)|uniprotkb:Plasma membrane calcium ATPase isoform 2(gene name synonym)|uniprotkb:Plasma membrane calcium pump isoform 2(gene name synonym)|uniprotkb:Atp2b2(gene name)|psi-mi:Atp2b2(display_short)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Martins et al. (2018)	imex:IM-28469|pubmed:29476059	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26439741|imex:IM-28469-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSRNOG00000016271(gene)|ensembl:ENSRNOT00000023037(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001540"(amyloid-beta binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0010008"(endosome membrane)|go:"GO:0030660"(Golgi-associated vesicle membrane)|go:"GO:0031301"(integral component of organelle membrane)|go:"GO:0042985"(negative regulation of amyloid precursor protein biosynthetic process)|interpro:IPR007084(BRICHOS)|interpro:IPR040145|mint:Q5XIE8|refseq:NP_001006964.1|rgd:620727	rgd:2176|refseq:NP_036640.1|interpro:IPR022141|interpro:IPR008250(E1-E2 ATPase-associated region)|interpro:IPR006408(Calcium-translocating P-type ATPase, PMCA-type)|interpro:IPR006068(ATPase, P-type cation-transporter, C-terminal)|interpro:IPR004014(ATPase, P-type cation-transporter, N-terminal)|interpro:IPR023299|interpro:IPR001757(ATPase, P-type, K/Mg/Cd/Cu/Zn/Na/Ca/Na/H-transporter)|interpro:IPR018303|interpro:IPR023298|interpro:IPR044492|go:"GO:0000902"(cell morphogenesis)|go:"GO:0003407"(neural retina development)|go:"GO:0005388"(P-type calcium transporter activity)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0005929"(cilium)|go:"GO:0006816"(calcium ion transport)|go:"GO:0006874"(cellular calcium ion homeostasis)|go:"GO:0006996"(organelle organization)|go:"GO:0007420"(brain development)|go:"GO:0007595"(lactation)|go:"GO:0007605"(sensory perception of sound)|go:"GO:0007626"(locomotory behavior)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008361"(regulation of cell size)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0019829"(ATPase-coupled cation transmembrane transporter activity)|go:"GO:0021549"(cerebellum development)|go:"GO:0021692"(cerebellar Purkinje cell layer morphogenesis)|go:"GO:0021702"(cerebellar Purkinje cell differentiation)|go:"GO:0021707"(cerebellar granule cell differentiation)|go:"GO:0030165"(PDZ domain binding)|go:"GO:0030182"(neuron differentiation)|go:"GO:0030425"(dendrite)|go:"GO:0030899"(calcium-dependent ATPase activity)|go:"GO:0032591"(dendritic spine membrane)|go:"GO:0032809"(neuronal cell body membrane)|go:"GO:0035254"(glutamate receptor binding)|go:"GO:0040011"(locomotion)|go:"GO:0042428"(serotonin metabolic process)|go:"GO:0042472"(inner ear morphogenesis)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0045121"(membrane raft)|go:"GO:0045299"(otolith mineralization)|go:"GO:0046068"(cGMP metabolic process)|go:"GO:0046872"(metal ion binding)|go:"GO:0048167"(regulation of synaptic plasticity)|go:"GO:0048839"(inner ear development)|go:"GO:0050808"(synapse organization)|go:"GO:0050885"(neuromuscular process controlling balance)|go:"GO:0050910"(detection of mechanical stimulus involved in sensory perception of sound)|go:"GO:0051480"(regulation of cytosolic calcium ion concentration)|go:"GO:0051928"(positive regulation of calcium ion transport)|go:"GO:0060088"(auditory receptor cell stereocilium organization)|go:"GO:0060113"(inner ear receptor cell differentiation)|go:"GO:0090102"(cochlea development)|go:"GO:0098688"(parallel fiber to Purkinje cell synapse)|go:"GO:0098839"(postsynaptic density membrane)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0098982"(GABA-ergic synapse)|go:"GO:0099055"(integral component of postsynaptic membrane)|go:"GO:0099059"(integral component of presynaptic active zone membrane)|go:"GO:0099061"(integral component of postsynaptic density membrane)|go:"GO:1905056"(P-type calcium transporter activity involved in regulation of presynaptic cytosolic calcium ion concentration)|go:"GO:1905059"(P-type calcium transporter activity involved in regulation of postsynaptic cytosolic calcium ion concentration)|reactome:R-RNO-418359|reactome:R-RNO-5578775|reactome:R-RNO-936837|interpro:IPR023214|interpro:IPR030322|interpro:IPR036412|mint:P11506	-	-	-	figure legend:st1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10116(rat-brain-cortex)|taxid:10116(Rattus norvegicus brain cortex)	-	2020/10/30	2020/10/30	rogid:DtE+ZXAZKdCMvUW5K+jXQ5bH07M10116	rogid:k3C9xaSxSDoPYcT/KGFNtZiBOj810116	rigid:3wclwrjZRvafcOruQOYnegkn54c	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q5XIE8	uniprotkb:P11505	intact:EBI-15348306|ensembl:ENSRNOP00000023037	intact:EBI-11689586|uniprotkb:Q63442|uniprotkb:Q9R1L7	psi-mi:itm2b_rat(display_long)|uniprotkb:Itm2b(gene name)|psi-mi:Itm2b(display_short)|uniprotkb:Immature BRI2(gene name synonym)|uniprotkb:Transmembrane protein BRI(gene name synonym)	psi-mi:at2b1_rat(display_long)|uniprotkb:Plasma membrane calcium ATPase isoform 1(gene name synonym)|uniprotkb:Plasma membrane calcium pump isoform 1(gene name synonym)|uniprotkb:Atp2b1(gene name)|psi-mi:Atp2b1(display_short)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Martins et al. (2018)	imex:IM-28469|pubmed:29476059	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26439741|imex:IM-28469-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSRNOG00000016271(gene)|ensembl:ENSRNOT00000023037(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001540"(amyloid-beta binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0010008"(endosome membrane)|go:"GO:0030660"(Golgi-associated vesicle membrane)|go:"GO:0031301"(integral component of organelle membrane)|go:"GO:0042985"(negative regulation of amyloid precursor protein biosynthetic process)|interpro:IPR007084(BRICHOS)|interpro:IPR040145|mint:Q5XIE8|refseq:NP_001006964.1|rgd:620727	mint:P11505|refseq:NP_445763.1|interpro:IPR022141|interpro:IPR006068(ATPase, P-type cation-transporter, C-terminal)|interpro:IPR004014(ATPase, P-type cation-transporter, N-terminal)|interpro:IPR023299|interpro:IPR018303|interpro:IPR023298|interpro:IPR008250(E1-E2 ATPase-associated region)|interpro:IPR006408(Calcium-translocating P-type ATPase, PMCA-type)|interpro:IPR001757(ATPase, P-type, K/Mg/Cd/Cu/Zn/Na/Ca/Na/H-transporter)|rgd:621303|go:"GO:0001772"(immunological synapse)|go:"GO:0001818"(negative regulation of cytokine production)|go:"GO:0003056"(regulation of vascular associated smooth muscle contraction)|go:"GO:0003407"(neural retina development)|go:"GO:0005388"(P-type calcium transporter activity)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006874"(cellular calcium ion homeostasis)|go:"GO:0007420"(brain development)|go:"GO:0007568"(aging)|go:"GO:0008217"(regulation of blood pressure)|go:"GO:0009409"(response to cold)|go:"GO:0009898"(cytoplasmic side of plasma membrane)|go:"GO:0015085"(calcium ion transmembrane transporter activity)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0030165"(PDZ domain binding)|go:"GO:0030285"(integral component of synaptic vesicle membrane)|go:"GO:0030501"(positive regulation of bone mineralization)|go:"GO:0032590"(dendrite membrane)|go:"GO:0032591"(dendritic spine membrane)|go:"GO:0032809"(neuronal cell body membrane)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0045121"(membrane raft)|go:"GO:0045177"(apical part of cell)|go:"GO:0046872"(metal ion binding)|go:"GO:0051480"(regulation of cytosolic calcium ion concentration)|go:"GO:0051481"(negative regulation of cytosolic calcium ion concentration)|go:"GO:0051928"(positive regulation of calcium ion transport)|go:"GO:0071305"(cellular response to vitamin D)|go:"GO:0071386"(cellular response to corticosterone stimulus)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0098982"(GABA-ergic synapse)|go:"GO:0099056"(integral component of presynaptic membrane)|go:"GO:0099059"(integral component of presynaptic active zone membrane)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|go:"GO:1900076"(regulation of cellular response to insulin stimulus)|go:"GO:1901660"(calcium ion export)|go:"GO:1905056"(P-type calcium transporter activity involved in regulation of presynaptic cytosolic calcium ion concentration)|go:"GO:1990034"(calcium ion export across plasma membrane)|reactome:R-RNO-418359|reactome:R-RNO-5578775|reactome:R-RNO-936837|go:"GO:0019829"(ATPase-coupled cation transmembrane transporter activity)|interpro:IPR023214|interpro:IPR044492|interpro:IPR030320|interpro:IPR036412	-	-	-	figure legend:st1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10116(rat-brain-cortex)|taxid:10116(Rattus norvegicus brain cortex)	-	2020/10/30	2020/10/30	rogid:DtE+ZXAZKdCMvUW5K+jXQ5bH07M10116	rogid:qd0uJavojqO86ByVuj5YhI/lROE10116	rigid:3wclwrjZRvafcOruQOYnegkn54c	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q5XIE8	uniprotkb:O08662	intact:EBI-15348306|ensembl:ENSRNOP00000023037	intact:EBI-22259134|uniprotkb:A0A0G2K2J3	psi-mi:itm2b_rat(display_long)|uniprotkb:Itm2b(gene name)|psi-mi:Itm2b(display_short)|uniprotkb:Immature BRI2(gene name synonym)|uniprotkb:Transmembrane protein BRI(gene name synonym)	psi-mi:pi4ka_rat(display_long)|uniprotkb:Pi4ka(gene name)|psi-mi:Pi4ka(display_short)|uniprotkb:Pik4ca(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Martins et al. (2018)	imex:IM-28469|pubmed:29476059	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26439741|imex:IM-28469-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSRNOG00000016271(gene)|ensembl:ENSRNOT00000023037(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001540"(amyloid-beta binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0010008"(endosome membrane)|go:"GO:0030660"(Golgi-associated vesicle membrane)|go:"GO:0031301"(integral component of organelle membrane)|go:"GO:0042985"(negative regulation of amyloid precursor protein biosynthetic process)|interpro:IPR007084(BRICHOS)|interpro:IPR040145|mint:Q5XIE8|refseq:NP_001006964.1|rgd:620727	go:"GO:0030660"(Golgi-associated vesicle membrane)|go:"GO:0039694"(viral RNA genome replication)|go:"GO:0016310"(phosphorylation)|go:"GO:0044803"(multi-organism membrane organization)|go:"GO:0046786"(viral replication complex formation and maintenance)|go:"GO:0046854"(phosphatidylinositol phosphate biosynthetic process)|go:"GO:0048015"(phosphatidylinositol-mediated signaling)|go:"GO:0052742"(phosphatidylinositol kinase activity)|reactome:R-RNO-1483248|reactome:R-RNO-1660514|go:"GO:0004430"(1-phosphatidylinositol 4-kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0016020"(membrane)|go:"GO:0016301"(kinase activity)|mint:O08662|refseq:NP_071637.1|interpro:IPR016024(Armadillo-type fold)|interpro:IPR011009(Protein kinase-like)|interpro:IPR000403(Phosphatidylinositol 3- and 4-kinase, catalytic)|interpro:IPR036940|interpro:IPR018936|interpro:IPR001263(Phosphoinositide 3-kinase accessory region PIK)|interpro:IPR042236|interpro:IPR015433(Phosphatidylinositol Kinase)|rgd:621213	-	-	-	figure legend:st1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10116(rat-brain-cortex)|taxid:10116(Rattus norvegicus brain cortex)	-	2020/10/30	2020/10/30	rogid:DtE+ZXAZKdCMvUW5K+jXQ5bH07M10116	rogid:MBJniuzZ1HzFbuLZWp4srJdCLCY10116	rigid:3wclwrjZRvafcOruQOYnegkn54c	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q5XIE8	uniprotkb:Q642G4	intact:EBI-15348306|ensembl:ENSRNOP00000023037	intact:EBI-15749292|ensembl:ENSRNOP00000018167|uniprotkb:Q9Z2Z4	psi-mi:itm2b_rat(display_long)|uniprotkb:Itm2b(gene name)|psi-mi:Itm2b(display_short)|uniprotkb:Immature BRI2(gene name synonym)|uniprotkb:Transmembrane protein BRI(gene name synonym)	psi-mi:pex14_rat(display_long)|uniprotkb:Pex14(gene name)|psi-mi:Pex14(display_short)|uniprotkb:PTS1 receptor-docking protein(gene name synonym)|uniprotkb:Peroxin-14(gene name synonym)|uniprotkb:Peroxisomal membrane anchor protein PEX14(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Martins et al. (2018)	imex:IM-28469|pubmed:29476059	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26439741|imex:IM-28469-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSRNOG00000016271(gene)|ensembl:ENSRNOT00000023037(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001540"(amyloid-beta binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0010008"(endosome membrane)|go:"GO:0030660"(Golgi-associated vesicle membrane)|go:"GO:0031301"(integral component of organelle membrane)|go:"GO:0042985"(negative regulation of amyloid precursor protein biosynthetic process)|interpro:IPR007084(BRICHOS)|interpro:IPR040145|mint:Q5XIE8|refseq:NP_001006964.1|rgd:620727	ensembl:ENSRNOG00000013498(gene)|ensembl:ENSRNOT00000018167(transcript)|go:"GO:0001650"(fibrillar center)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005777"(peroxisome)|go:"GO:0005778"(peroxisomal membrane)|go:"GO:0007031"(peroxisome organization)|go:"GO:0008017"(microtubule binding)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016558"(protein import into peroxisome matrix)|go:"GO:0016560"(protein import into peroxisome matrix, docking)|go:"GO:0016561"(protein import into peroxisome matrix, translocation)|go:"GO:0032091"(negative regulation of protein binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034453"(microtubule anchoring)|go:"GO:0036250"(peroxisome transport along microtubule)|go:"GO:0042802"(identical protein binding)|go:"GO:0043433"(negative regulation of DNA-binding transcription factor activity)|go:"GO:0044721"(protein import into peroxisome matrix, substrate release)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0047485"(protein N-terminus binding)|go:"GO:0048487"(beta-tubulin binding)|go:"GO:0065003"(protein-containing complex assembly)|go:"GO:1990429"(peroxisomal importomer complex)|interpro:IPR006785(Peroxisome membrane anchor protein Pex14p, N-terminal)|interpro:IPR025655|interpro:IPR036388|mint:Q642G4|rcsb pdb:3FF5|reactome:R-RNO-8866654|reactome:R-RNO-9033241|reactome:R-RNO-9603798|dip:DIP-58546N|refseq:NP_742060.1|rgd:68336	-	-	caution:This sequence has been withdrawn from Uniprot.|crc64:C9DFFC0DD4DD45C8	figure legend:st1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10116(rat-brain-cortex)|taxid:10116(Rattus norvegicus brain cortex)	-	2020/10/30	2020/10/30	rogid:DtE+ZXAZKdCMvUW5K+jXQ5bH07M10116	rogid:IF2ZW63sZzMgFWFbGJgI+0+dcjs10116	rigid:3wclwrjZRvafcOruQOYnegkn54c	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q5XIE8	uniprotkb:P35704	intact:EBI-15348306|ensembl:ENSRNOP00000023037	intact:EBI-917371|uniprotkb:Q6PDV3	psi-mi:itm2b_rat(display_long)|uniprotkb:Itm2b(gene name)|psi-mi:Itm2b(display_short)|uniprotkb:Immature BRI2(gene name synonym)|uniprotkb:Transmembrane protein BRI(gene name synonym)	psi-mi:prdx2_rat(display_long)|uniprotkb:Thioredoxin peroxidase 1(gene name synonym)|uniprotkb:Thioredoxin-dependent peroxide reductase 1(gene name synonym)|uniprotkb:Thiol-specific antioxidant protein(gene name synonym)|uniprotkb:Prdx2(gene name)|psi-mi:Prdx2(display_short)|uniprotkb:Tdpx1(gene name synonym)|uniprotkb:Thioredoxin-dependent peroxiredoxin 2(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Martins et al. (2018)	imex:IM-28469|pubmed:29476059	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26439741|imex:IM-28469-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSRNOG00000016271(gene)|ensembl:ENSRNOT00000023037(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001540"(amyloid-beta binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0010008"(endosome membrane)|go:"GO:0030660"(Golgi-associated vesicle membrane)|go:"GO:0031301"(integral component of organelle membrane)|go:"GO:0042985"(negative regulation of amyloid precursor protein biosynthetic process)|interpro:IPR007084(BRICHOS)|interpro:IPR040145|mint:Q5XIE8|refseq:NP_001006964.1|rgd:620727	rgd:3838|refseq:NP_058865.1|interpro:IPR000866(Alkyl hydroperoxide reductase/ Thiol specific antioxidant/ Mal allergen)|interpro:IPR024706|interpro:IPR019479|mint:P35704|interpro:IPR013766(Thioredoxin domain)|refseq:XP_006255306.1|interpro:IPR036249|go:"GO:0000187"(obsolete activation of MAPK activity)|go:"GO:0002357"(defense response to tumor cell)|go:"GO:0002536"(respiratory burst involved in inflammatory response)|go:"GO:0005829"(cytosol)|go:"GO:0006979"(response to oxidative stress)|go:"GO:0008379"(thioredoxin peroxidase activity)|go:"GO:0010310"(regulation of hydrogen peroxide metabolic process)|go:"GO:0016209"(antioxidant activity)|go:"GO:0019430"(removal of superoxide radicals)|go:"GO:0030194"(positive regulation of blood coagulation)|go:"GO:0031665"(negative regulation of lipopolysaccharide-mediated signaling pathway)|go:"GO:0032088"(negative regulation of NF-kappaB transcription factor activity)|go:"GO:0032496"(response to lipopolysaccharide)|go:"GO:0034599"(cellular response to oxidative stress)|go:"GO:0042098"(T cell proliferation)|go:"GO:0042743"(hydrogen peroxide metabolic process)|go:"GO:0042744"(hydrogen peroxide catabolic process)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0045321"(leukocyte activation)|go:"GO:0045454"(cell redox homeostasis)|go:"GO:0045581"(negative regulation of T cell differentiation)|go:"GO:0048538"(thymus development)|go:"GO:0048872"(homeostasis of number of cells)|go:"GO:2001237"(negative regulation of extrinsic apoptotic signaling pathway)|go:"GO:2001240"(negative regulation of extrinsic apoptotic signaling pathway in absence of ligand)|reactome:R-RNO-3299685|reactome:R-RNO-5628897	-	-	-	figure legend:st1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10116(rat-brain-cortex)|taxid:10116(Rattus norvegicus brain cortex)	-	2020/10/30	2020/10/30	rogid:DtE+ZXAZKdCMvUW5K+jXQ5bH07M10116	rogid:pAorkTLST5+rViOjvDlhw2edzQE10116	rigid:3wclwrjZRvafcOruQOYnegkn54c	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q5XIE8	uniprotkb:P04218	intact:EBI-15348306|ensembl:ENSRNOP00000023037	intact:EBI-915817	psi-mi:itm2b_rat(display_long)|uniprotkb:Itm2b(gene name)|psi-mi:Itm2b(display_short)|uniprotkb:Immature BRI2(gene name synonym)|uniprotkb:Transmembrane protein BRI(gene name synonym)	psi-mi:ox2g_rat(display_long)|uniprotkb:MRC OX-2 antigen(gene name synonym)|uniprotkb:Cd200(gene name)|psi-mi:Cd200(display_short)|uniprotkb:Mox2(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Martins et al. (2018)	imex:IM-28469|pubmed:29476059	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26439741|imex:IM-28469-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSRNOG00000016271(gene)|ensembl:ENSRNOT00000023037(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001540"(amyloid-beta binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0010008"(endosome membrane)|go:"GO:0030660"(Golgi-associated vesicle membrane)|go:"GO:0031301"(integral component of organelle membrane)|go:"GO:0042985"(negative regulation of amyloid precursor protein biosynthetic process)|interpro:IPR007084(BRICHOS)|interpro:IPR040145|mint:Q5XIE8|refseq:NP_001006964.1|rgd:620727	go:"GO:2000405"(negative regulation of T cell migration)|reactome:R-RNO-198933|go:"GO:0005886"(plasma membrane)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0009986"(cell surface)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030424"(axon)|go:"GO:0032088"(negative regulation of NF-kappaB transcription factor activity)|go:"GO:0032715"(negative regulation of interleukin-6 production)|go:"GO:0032793"(positive regulation of CREB transcription factor activity)|go:"GO:0034113"(heterotypic cell-cell adhesion)|go:"GO:0043005"(neuron projection)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043031"(negative regulation of macrophage activation)|go:"GO:0044297"(cell body)|go:"GO:0050776"(regulation of immune response)|go:"GO:0071636"(positive regulation of transforming growth factor beta production)|go:"GO:0086080"(protein binding involved in heterotypic cell-cell adhesion)|go:"GO:0098609"(cell-cell adhesion)|go:"GO:0150072"(positive regulation of arginase activity)|go:"GO:0150074"(positive regulation of protein-glutamine gamma-glutamyltransferase activity)|go:"GO:0150077"(regulation of neuroinflammatory response)|go:"GO:0150079"(negative regulation of neuroinflammatory response)|go:"GO:1901215"(negative regulation of neuron death)|go:"GO:1904465"(negative regulation of matrix metallopeptidase secretion)|go:"GO:1905522"(negative regulation of macrophage migration)|mint:P04218|interpro:IPR003599(Immunoglobulin subtype)|interpro:IPR033321|rgd:3104|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR013151(Immunoglobulin)|interpro:IPR013106(Immunoglobulin V-set)|interpro:IPR036179	-	-	-	figure legend:st1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10116(rat-brain-cortex)|taxid:10116(Rattus norvegicus brain cortex)	-	2020/10/30	2020/10/30	rogid:DtE+ZXAZKdCMvUW5K+jXQ5bH07M10116	rogid:BHy/iOl1Toxvv9wigUj/l80cVsA10116	rigid:3wclwrjZRvafcOruQOYnegkn54c	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q5XIE8	uniprotkb:A1L1I3	intact:EBI-15348306|ensembl:ENSRNOP00000023037	intact:EBI-26438930|ensembl:ENSRNOP00000054039	psi-mi:itm2b_rat(display_long)|uniprotkb:Itm2b(gene name)|psi-mi:Itm2b(display_short)|uniprotkb:Immature BRI2(gene name synonym)|uniprotkb:Transmembrane protein BRI(gene name synonym)	psi-mi:numbl_rat(display_long)|uniprotkb:Numbl(gene name)|psi-mi:Numbl(display_short)|uniprotkb:Nbl(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Martins et al. (2018)	imex:IM-28469|pubmed:29476059	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26439741|imex:IM-28469-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSRNOG00000016271(gene)|ensembl:ENSRNOT00000023037(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001540"(amyloid-beta binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0010008"(endosome membrane)|go:"GO:0030660"(Golgi-associated vesicle membrane)|go:"GO:0031301"(integral component of organelle membrane)|go:"GO:0042985"(negative regulation of amyloid precursor protein biosynthetic process)|interpro:IPR007084(BRICHOS)|interpro:IPR040145|mint:Q5XIE8|refseq:NP_001006964.1|rgd:620727	ensembl:ENSRNOG00000020867(gene)|ensembl:ENSRNOT00000057213(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0007399"(nervous system development)|go:"GO:0007405"(neuroblast proliferation)|go:"GO:0007409"(axonogenesis)|go:"GO:0019221"(cytokine-mediated signaling pathway)|go:"GO:0019538"(protein metabolic process)|go:"GO:0021670"(lateral ventricle development)|go:"GO:0021849"(neuroblast division in subventricular zone)|go:"GO:0030900"(forebrain development)|go:"GO:0034332"(adherens junction organization)|go:"GO:0050769"(positive regulation of neurogenesis)|go:"GO:0050775"(positive regulation of dendrite morphogenesis)|interpro:IPR006020(Phosphotyrosine interaction region)|interpro:IPR010449(NUMB phenylalanine-rich)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR016698(Numb/numb-like)|mint:A1L1I3|refseq:XP_006228629.1|rgd:1307579	-	-	-	figure legend:st1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10116(rat-brain-cortex)|taxid:10116(Rattus norvegicus brain cortex)	-	2020/10/30	2020/10/30	rogid:DtE+ZXAZKdCMvUW5K+jXQ5bH07M10116	rogid:yau7n13K/gB2fnpZO/dI00Bcgh010116	rigid:3wclwrjZRvafcOruQOYnegkn54c	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q5XIE8	uniprotkb:Q9EPI6	intact:EBI-15348306|ensembl:ENSRNOP00000023037	intact:EBI-6899705|uniprotkb:Q5PPF6|uniprotkb:Q7TSC6|uniprotkb:Q7TSC8|uniprotkb:Q9EPI4|uniprotkb:Q9EPI5	psi-mi:itm2b_rat(display_long)|uniprotkb:Itm2b(gene name)|psi-mi:Itm2b(display_short)|uniprotkb:Immature BRI2(gene name synonym)|uniprotkb:Transmembrane protein BRI(gene name synonym)	psi-mi:nsmf_rat(display_long)|uniprotkb:Nsmf(gene name)|psi-mi:Nsmf(display_short)|uniprotkb:Jac(gene name synonym)|uniprotkb:Nelf(gene name synonym)|uniprotkb:Juxtasynaptic attractor of caldendrin on dendritic boutons protein(gene name synonym)|uniprotkb:Nasal embryonic luteinizing hormone-releasing hormone factor(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Martins et al. (2018)	imex:IM-28469|pubmed:29476059	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26439741|imex:IM-28469-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSRNOG00000016271(gene)|ensembl:ENSRNOT00000023037(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001540"(amyloid-beta binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0010008"(endosome membrane)|go:"GO:0030660"(Golgi-associated vesicle membrane)|go:"GO:0031301"(integral component of organelle membrane)|go:"GO:0042985"(negative regulation of amyloid precursor protein biosynthetic process)|interpro:IPR007084(BRICHOS)|interpro:IPR040145|mint:Q5XIE8|refseq:NP_001006964.1|rgd:620727	go:"GO:0014069"(postsynaptic density)|go:"GO:0016020"(membrane)|go:"GO:0016363"(nuclear matrix)|go:"GO:0030425"(dendrite)|go:"GO:0030863"(cortical cytoskeleton)|go:"GO:0031965"(nuclear membrane)|go:"GO:0035307"(positive regulation of protein dephosphorylation)|go:"GO:0043005"(neuron projection)|go:"GO:0043197"(dendritic spine)|go:"GO:0043204"(perikaryon)|go:"GO:0043523"(regulation of neuron apoptotic process)|go:"GO:0045202"(synapse)|go:"GO:0048168"(regulation of neuronal synaptic plasticity)|go:"GO:0048306"(calcium-dependent protein binding)|go:"GO:0048814"(regulation of dendrite morphogenesis)|go:"GO:0071230"(cellular response to amino acid stimulus)|go:"GO:0071257"(cellular response to electrical stimulus)|go:"GO:0005886"(plasma membrane)|go:"GO:0000791"(euchromatin)|go:"GO:0005634"(nucleus)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005737"(cytoplasm)|go:"GO:0071371"(cellular response to gonadotropin stimulus)|go:"GO:0098794"(postsynapse)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099527"(postsynapse to nucleus signaling pathway)|go:"GO:2001224"(positive regulation of neuron migration)|go:"GO:0097440"(apical dendrite)|mint:Q9EPI6|interpro:IPR033374|rgd:619819|refseq:NP_001257555.1|refseq:NP_001257556.1|refseq:NP_001257557.1|refseq:NP_476538.2	-	-	-	figure legend:st1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10116(rat-brain-cortex)|taxid:10116(Rattus norvegicus brain cortex)	-	2020/10/30	2020/10/30	rogid:DtE+ZXAZKdCMvUW5K+jXQ5bH07M10116	rogid:7roymdKtL+QSCC6O/qfhzsLvSaA10116	rigid:3wclwrjZRvafcOruQOYnegkn54c	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q5XIE8	uniprotkb:P97546	intact:EBI-15348306|ensembl:ENSRNOP00000023037	intact:EBI-26438868|ensembl:ENSRNOP00000012091|uniprotkb:P97547|uniprotkb:Q6IRE8	psi-mi:itm2b_rat(display_long)|uniprotkb:Itm2b(gene name)|psi-mi:Itm2b(display_short)|uniprotkb:Immature BRI2(gene name synonym)|uniprotkb:Transmembrane protein BRI(gene name synonym)	psi-mi:nptn_rat(display_long)|uniprotkb:Nptn(gene name)|psi-mi:Nptn(display_short)|uniprotkb:Sdfr1(gene name synonym)|uniprotkb:Sdr1(gene name synonym)|uniprotkb:Glycoprotein 55/65(gene name synonym)|uniprotkb:Stromal cell-derived receptor 1(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Martins et al. (2018)	imex:IM-28469|pubmed:29476059	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26439741|imex:IM-28469-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSRNOG00000016271(gene)|ensembl:ENSRNOT00000023037(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001540"(amyloid-beta binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0010008"(endosome membrane)|go:"GO:0030660"(Golgi-associated vesicle membrane)|go:"GO:0031301"(integral component of organelle membrane)|go:"GO:0042985"(negative regulation of amyloid precursor protein biosynthetic process)|interpro:IPR007084(BRICHOS)|interpro:IPR040145|mint:Q5XIE8|refseq:NP_001006964.1|rgd:620727	ensembl:ENSRNOG00000009029(gene)|ensembl:ENSRNOT00000012091(transcript)|go:"GO:0001772"(immunological synapse)|go:"GO:0001818"(negative regulation of cytokine production)|go:"GO:0001934"(positive regulation of protein phosphorylation)|go:"GO:0005105"(type 1 fibroblast growth factor receptor binding)|go:"GO:0005886"(plasma membrane)|go:"GO:0006874"(cellular calcium ion homeostasis)|go:"GO:0007156"(homophilic cell adhesion via plasma membrane adhesion molecules)|go:"GO:0007204"(positive regulation of cytosolic calcium ion concentration)|go:"GO:0007411"(axon guidance)|go:"GO:0008542"(visual learning)|go:"GO:0009986"(cell surface)|go:"GO:0010976"(positive regulation of neuron projection development)|go:"GO:0014069"(postsynaptic density)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030155"(regulation of cell adhesion)|go:"GO:0030424"(axon)|go:"GO:0030425"(dendrite)|go:"GO:0042734"(presynaptic membrane)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0045211"(postsynaptic membrane)|go:"GO:0045743"(positive regulation of fibroblast growth factor receptor signaling pathway)|go:"GO:0048170"(positive regulation of long-term neuronal synaptic plasticity)|go:"GO:0050804"(modulation of chemical synaptic transmission)|go:"GO:0050808"(synapse organization)|go:"GO:0050839"(cell adhesion molecule binding)|go:"GO:0060077"(inhibitory synapse)|go:"GO:0060291"(long-term synaptic potentiation)|go:"GO:0070374"(positive regulation of ERK1 and ERK2 cascade)|go:"GO:0070593"(dendrite self-avoidance)|go:"GO:0097060"(synaptic membrane)|go:"GO:0098632"(cell-cell adhesion mediator activity)|go:"GO:0098685"(Schaffer collateral - CA1 synapse)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0098982"(GABA-ergic synapse)|go:"GO:0099059"(integral component of presynaptic active zone membrane)|go:"GO:0099061"(integral component of postsynaptic density membrane)|go:"GO:0099557"(trans-synaptic signaling by trans-synaptic complex, modulating synaptic transmission)|go:"GO:1900273"(positive regulation of long-term synaptic potentiation)|go:"GO:1902683"(regulation of receptor localization to synapse)|go:"GO:1903829"(positive regulation of protein localization)|go:"GO:1904861"(excitatory synapse assembly)|interpro:IPR003598(Immunoglobulin subtype 2)|interpro:IPR003599(Immunoglobulin subtype)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR027112|interpro:IPR036179|interpro:IPR043204|mint:P97546|rcsb pdb:2WV3|refseq:NP_062253.1|refseq:XP_006243236.1|refseq:XP_008764552.1|rgd:620296	-	-	-	figure legend:st1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10116(rat-brain-cortex)|taxid:10116(Rattus norvegicus brain cortex)	-	2020/10/30	2020/10/30	rogid:DtE+ZXAZKdCMvUW5K+jXQ5bH07M10116	rogid:EKyW/CbXn0Efgu9ZnFK+L4S+8c410116	rigid:3wclwrjZRvafcOruQOYnegkn54c	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q5XIE8	uniprotkb:Q9ESI7	intact:EBI-15348306|ensembl:ENSRNOP00000023037	intact:EBI-26438834	psi-mi:itm2b_rat(display_long)|uniprotkb:Itm2b(gene name)|psi-mi:Itm2b(display_short)|uniprotkb:Immature BRI2(gene name synonym)|uniprotkb:Transmembrane protein BRI(gene name synonym)	psi-mi:dcx_rat(display_long)|uniprotkb:Dcx(gene name)|psi-mi:Dcx(display_short)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Martins et al. (2018)	imex:IM-28469|pubmed:29476059	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26439741|imex:IM-28469-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSRNOG00000016271(gene)|ensembl:ENSRNOT00000023037(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001540"(amyloid-beta binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0010008"(endosome membrane)|go:"GO:0030660"(Golgi-associated vesicle membrane)|go:"GO:0031301"(integral component of organelle membrane)|go:"GO:0042985"(negative regulation of amyloid precursor protein biosynthetic process)|interpro:IPR007084(BRICHOS)|interpro:IPR040145|mint:Q5XIE8|refseq:NP_001006964.1|rgd:620727	go:"GO:0030426"(growth cone)|go:"GO:0035082"(axoneme assembly)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0042461"(photoreceptor cell development)|go:"GO:0043005"(neuron projection)|go:"GO:0043025"(neuronal cell body)|go:"GO:0045807"(positive regulation of endocytosis)|go:"GO:0048672"(positive regulation of collateral sprouting)|go:"GO:0048675"(axon extension)|go:"GO:0048813"(dendrite morphogenesis)|go:"GO:0051602"(response to electrical stimulus)|go:"GO:0060041"(retina development in camera-type eye)|go:"GO:0030425"(dendrite)|go:"GO:0001764"(neuron migration)|go:"GO:0005737"(cytoplasm)|go:"GO:0005874"(microtubule)|go:"GO:0005930"(axoneme)|go:"GO:0007420"(brain development)|go:"GO:0008017"(microtubule binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0021510"(spinal cord development)|go:"GO:0021766"(hippocampus development)|go:"GO:0021819"(layer formation in cerebral cortex)|go:"GO:0021860"(pyramidal neuron development)|go:"GO:0021952"(central nervous system projection neuron axonogenesis)|go:"GO:0030424"(axon)|mint:Q9ESI7|interpro:IPR017302(Neuronal migration protein doublecortin)|interpro:IPR003533(Doublecortin)|interpro:IPR036572|interpro:IPR040163|rgd:620670	-	-	-	figure legend:st1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10116(rat-brain-cortex)|taxid:10116(Rattus norvegicus brain cortex)	-	2020/10/30	2020/10/30	rogid:DtE+ZXAZKdCMvUW5K+jXQ5bH07M10116	rogid:+Zp4BV29yDDqqREt2VeO7Ylxi4c10116	rigid:3wclwrjZRvafcOruQOYnegkn54c	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q5XIE8	uniprotkb:P07936	intact:EBI-15348306|ensembl:ENSRNOP00000023037	intact:EBI-26438795|ensembl:ENSRNOP00000002091|uniprotkb:A0JPM4	psi-mi:itm2b_rat(display_long)|uniprotkb:Itm2b(gene name)|psi-mi:Itm2b(display_short)|uniprotkb:Immature BRI2(gene name synonym)|uniprotkb:Transmembrane protein BRI(gene name synonym)	psi-mi:neum_rat(display_long)|uniprotkb:Gap43(gene name)|psi-mi:Gap43(display_short)|uniprotkb:Axonal membrane protein GAP-43(gene name synonym)|uniprotkb:Growth-associated protein 43(gene name synonym)|uniprotkb:Protein F1(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Martins et al. (2018)	imex:IM-28469|pubmed:29476059	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26439741|imex:IM-28469-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSRNOG00000016271(gene)|ensembl:ENSRNOT00000023037(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001540"(amyloid-beta binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0010008"(endosome membrane)|go:"GO:0030660"(Golgi-associated vesicle membrane)|go:"GO:0031301"(integral component of organelle membrane)|go:"GO:0042985"(negative regulation of amyloid precursor protein biosynthetic process)|interpro:IPR007084(BRICHOS)|interpro:IPR040145|mint:Q5XIE8|refseq:NP_001006964.1|rgd:620727	ensembl:ENSRNOG00000001528(gene)|ensembl:ENSRNOT00000002091(transcript)|go:"GO:0001786"(phosphatidylserine binding)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0007399"(nervous system development)|go:"GO:0007411"(axon guidance)|go:"GO:0010001"(glial cell differentiation)|go:"GO:0014069"(postsynaptic density)|go:"GO:0016198"(axon choice point recognition)|go:"GO:0030424"(axon)|go:"GO:0030425"(dendrite)|go:"GO:0030426"(growth cone)|go:"GO:0031103"(axon regeneration)|go:"GO:0031527"(filopodium membrane)|go:"GO:0032584"(growth cone membrane)|go:"GO:0035727"(lysophosphatidic acid binding)|go:"GO:0040008"(regulation of growth)|go:"GO:0042246"(tissue regeneration)|go:"GO:0043204"(perikaryon)|go:"GO:0045165"(cell fate commitment)|go:"GO:0051489"(regulation of filopodium assembly)|go:"GO:0071944"(cell periphery)|go:"GO:0098982"(GABA-ergic synapse)|go:"GO:0099150"(regulation of postsynaptic specialization assembly)|go:"GO:1901981"(phosphatidylinositol phosphate binding)|interpro:IPR000048(IQ calmodulin-binding region)|interpro:IPR001422("Neuromodulin (GAP-43)")|interpro:IPR017454("Neuromodulin (GAP-43), C-terminal")|interpro:IPR018243|interpro:IPR018947|interpro:IPR033137|mint:P07936|reactome:R-RNO-373760|refseq:NP_058891.1|rgd:62071	-	-	-	figure legend:st1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10116(rat-brain-cortex)|taxid:10116(Rattus norvegicus brain cortex)	-	2020/10/30	2020/10/30	rogid:DtE+ZXAZKdCMvUW5K+jXQ5bH07M10116	rogid:PI3nUZq+f76xlzN4ebj0gW06/XI10116	rigid:3wclwrjZRvafcOruQOYnegkn54c	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q5XIE8	uniprotkb:O35095	intact:EBI-15348306|ensembl:ENSRNOP00000023037	intact:EBI-8848768|uniprotkb:Q5PQW2|ensembl:ENSRNOP00000016229	psi-mi:itm2b_rat(display_long)|uniprotkb:Itm2b(gene name)|psi-mi:Itm2b(display_short)|uniprotkb:Immature BRI2(gene name synonym)|uniprotkb:Transmembrane protein BRI(gene name synonym)	psi-mi:ncdn_rat(display_long)|uniprotkb:Ncdn(gene name)|psi-mi:Ncdn(display_short)|uniprotkb:Neurite outgrowth-related protein from the rat brain(gene name synonym)|uniprotkb:Norbin(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Martins et al. (2018)	imex:IM-28469|pubmed:29476059	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26439741|imex:IM-28469-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSRNOG00000016271(gene)|ensembl:ENSRNOT00000023037(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001540"(amyloid-beta binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0010008"(endosome membrane)|go:"GO:0030660"(Golgi-associated vesicle membrane)|go:"GO:0031301"(integral component of organelle membrane)|go:"GO:0042985"(negative regulation of amyloid precursor protein biosynthetic process)|interpro:IPR007084(BRICHOS)|interpro:IPR040145|mint:Q5XIE8|refseq:NP_001006964.1|rgd:620727	refseq:XP_017449158.1|refseq:NP_445995.2|rgd:621734|ensembl:ENSRNOG00000011751(gene)|ensembl:ENSRNOT00000016230(transcript)|go:"GO:0005829"(cytosol)|go:"GO:0010008"(endosome membrane)|go:"GO:0016020"(membrane)|go:"GO:0030425"(dendrite)|go:"GO:0031175"(neuron projection development)|go:"GO:0043005"(neuron projection)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043204"(perikaryon)|go:"GO:0045453"(bone resorption)|go:"GO:0048168"(regulation of neuronal synaptic plasticity)|go:"GO:0098794"(postsynapse)|interpro:IPR008709(Neurochondrin)|interpro:IPR016024(Armadillo-type fold)|mint:O35095	-	-	-	figure legend:st1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10116(rat-brain-cortex)|taxid:10116(Rattus norvegicus brain cortex)	-	2020/10/30	2020/10/30	rogid:DtE+ZXAZKdCMvUW5K+jXQ5bH07M10116	rogid:c5PVnaZkTuwbQft0KK2SCy6pLM410116	rigid:3wclwrjZRvafcOruQOYnegkn54c	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q5XIE8	uniprotkb:Q64122	intact:EBI-15348306|ensembl:ENSRNOP00000023037	intact:EBI-22264413	psi-mi:itm2b_rat(display_long)|uniprotkb:Itm2b(gene name)|psi-mi:Itm2b(display_short)|uniprotkb:Immature BRI2(gene name synonym)|uniprotkb:Transmembrane protein BRI(gene name synonym)	psi-mi:myl9_rat(display_long)|uniprotkb:Myosin regulatory light chain 2, smooth muscle isoform(gene name synonym)|uniprotkb:Myosin regulatory light chain 9(gene name synonym)|uniprotkb:Myl9(gene name)|psi-mi:Myl9(display_short)|uniprotkb:Myrl2(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Martins et al. (2018)	imex:IM-28469|pubmed:29476059	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26439741|imex:IM-28469-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSRNOG00000016271(gene)|ensembl:ENSRNOT00000023037(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001540"(amyloid-beta binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0010008"(endosome membrane)|go:"GO:0030660"(Golgi-associated vesicle membrane)|go:"GO:0031301"(integral component of organelle membrane)|go:"GO:0042985"(negative regulation of amyloid precursor protein biosynthetic process)|interpro:IPR007084(BRICHOS)|interpro:IPR040145|mint:Q5XIE8|refseq:NP_001006964.1|rgd:620727	go:"GO:0001725"(stress fiber)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005938"(cell cortex)|go:"GO:0016460"(myosin II complex)|go:"GO:0030018"(Z disc)|go:"GO:0032036"(myosin heavy chain binding)|reactome:R-RNO-445355|reactome:R-RNO-5627123|mint:Q64122|rgd:1311235|refseq:NP_001094355.1|interpro:IPR011992(EF-Hand type)|interpro:IPR018247|interpro:IPR002048(Calcium-binding EF-hand)	-	-	-	figure legend:st1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10116(rat-brain-cortex)|taxid:10116(Rattus norvegicus brain cortex)	-	2020/10/30	2020/10/30	rogid:DtE+ZXAZKdCMvUW5K+jXQ5bH07M10116	rogid:B5PKy34lkLaGzjNoxpNkeVDAOU010116	rigid:3wclwrjZRvafcOruQOYnegkn54c	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q5XIE8	uniprotkb:Q6VBQ5	intact:EBI-15348306|ensembl:ENSRNOP00000023037	intact:EBI-11690880	psi-mi:itm2b_rat(display_long)|uniprotkb:Itm2b(gene name)|psi-mi:Itm2b(display_short)|uniprotkb:Immature BRI2(gene name synonym)|uniprotkb:Transmembrane protein BRI(gene name synonym)	psi-mi:myadm_rat(display_long)|uniprotkb:Myeloid up-regulated protein(gene name synonym)|uniprotkb:Myadm(gene name)|psi-mi:Myadm(display_short)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Martins et al. (2018)	imex:IM-28469|pubmed:29476059	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26439741|imex:IM-28469-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSRNOG00000016271(gene)|ensembl:ENSRNOT00000023037(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001540"(amyloid-beta binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0010008"(endosome membrane)|go:"GO:0030660"(Golgi-associated vesicle membrane)|go:"GO:0031301"(integral component of organelle membrane)|go:"GO:0042985"(negative regulation of amyloid precursor protein biosynthetic process)|interpro:IPR007084(BRICHOS)|interpro:IPR040145|mint:Q5XIE8|refseq:NP_001006964.1|rgd:620727	mint:Q6VBQ5|refseq:NP_899161.1|interpro:IPR008253(Marvel)|rgd:727835|go:"GO:0001726"(ruffle)|go:"GO:0001933"(negative regulation of protein phosphorylation)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0030837"(negative regulation of actin filament polymerization)|go:"GO:0030864"(cortical actin cytoskeleton)|go:"GO:0031579"(membrane raft organization)|go:"GO:0034115"(negative regulation of heterotypic cell-cell adhesion)|go:"GO:0045121"(membrane raft)|go:"GO:0061028"(establishment of endothelial barrier)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0090038"(negative regulation of protein kinase C signaling)|go:"GO:1900026"(positive regulation of substrate adhesion-dependent cell spreading)	-	-	-	figure legend:st1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10116(rat-brain-cortex)|taxid:10116(Rattus norvegicus brain cortex)	-	2020/10/30	2020/10/30	rogid:DtE+ZXAZKdCMvUW5K+jXQ5bH07M10116	rogid:7FqFwpFfKg0piOF+svNrOQ0OPiE10116	rigid:3wclwrjZRvafcOruQOYnegkn54c	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q5XIE8	uniprotkb:P02688	intact:EBI-15348306|ensembl:ENSRNOP00000023037	intact:EBI-1638296|uniprotkb:Q505J1|uniprotkb:Q8R4K6|uniprotkb:Q9Z1J4|uniprotkb:Q9Z1J5|uniprotkb:Q9Z1J6|ensembl:ENSRNOP00000022303	psi-mi:itm2b_rat(display_long)|uniprotkb:Itm2b(gene name)|psi-mi:Itm2b(display_short)|uniprotkb:Immature BRI2(gene name synonym)|uniprotkb:Transmembrane protein BRI(gene name synonym)	psi-mi:mbp_rat(display_long)|uniprotkb:Mbp(gene name)|psi-mi:Mbp(display_short)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Martins et al. (2018)	imex:IM-28469|pubmed:29476059	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26439741|imex:IM-28469-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSRNOG00000016271(gene)|ensembl:ENSRNOT00000023037(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001540"(amyloid-beta binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0010008"(endosome membrane)|go:"GO:0030660"(Golgi-associated vesicle membrane)|go:"GO:0031301"(integral component of organelle membrane)|go:"GO:0042985"(negative regulation of amyloid precursor protein biosynthetic process)|interpro:IPR007084(BRICHOS)|interpro:IPR040145|mint:Q5XIE8|refseq:NP_001006964.1|rgd:620727	rgd:3054|refseq:NP_001020462.1|refseq:NP_001020463.1|refseq:NP_001020464.1|refseq:NP_001020465.1|refseq:NP_058722.1|ensembl:ENSRNOG00000016516(gene)|ensembl:ENSRNOT00000022303(transcript)|go:"GO:0000165"(MAPK cascade)|go:"GO:0002020"(protease binding)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005886"(plasma membrane)|go:"GO:0007568"(aging)|go:"GO:0007605"(sensory perception of sound)|go:"GO:0009636"(response to toxic substance)|go:"GO:0009986"(cell surface)|go:"GO:0019911"(structural constituent of myelin sheath)|go:"GO:0032570"(response to progesterone)|go:"GO:0032755"(positive regulation of interleukin-6 production)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033269"(internode region of axon)|go:"GO:0034115"(negative regulation of heterotypic cell-cell adhesion)|go:"GO:0034612"(response to tumor necrosis factor)|go:"GO:0035633"(maintenance of blood-brain barrier)|go:"GO:0042552"(myelination)|go:"GO:0042995"(cell projection)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043209"(myelin sheath)|go:"GO:0043218"(compact myelin)|go:"GO:0046689"(response to mercury ion)|go:"GO:0050771"(negative regulation of axonogenesis)|go:"GO:0061024"(membrane organization)|go:"GO:0070542"(response to fatty acid)|go:"GO:0071944"(cell periphery)|go:"GO:1904685"(positive regulation of metalloendopeptidase activity)|go:"GO:2000343"("positive regulation of chemokine (C-X-C motif) ligand 2 production")|interpro:IPR000548(Myelin basic protein)|mint:P02688	-	-	-	figure legend:st1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10116(rat-brain-cortex)|taxid:10116(Rattus norvegicus brain cortex)	-	2020/10/30	2020/10/30	rogid:DtE+ZXAZKdCMvUW5K+jXQ5bH07M10116	rogid:FpS+fUURzQiiFgExomqEJYnGvNs10116	rigid:3wclwrjZRvafcOruQOYnegkn54c	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q5XIE8	uniprotkb:Q505J6	intact:EBI-15348306|ensembl:ENSRNOP00000023037	intact:EBI-26438774|ensembl:ENSRNOP00000015561	psi-mi:itm2b_rat(display_long)|uniprotkb:Itm2b(gene name)|psi-mi:Itm2b(display_short)|uniprotkb:Immature BRI2(gene name synonym)|uniprotkb:Transmembrane protein BRI(gene name synonym)	psi-mi:ghc2_rat(display_long)|uniprotkb:Slc25a18(gene name)|psi-mi:Slc25a18(display_short)|uniprotkb:"Glutamate/H(+) symporter 2"(gene name synonym)|uniprotkb:Solute carrier family 25 member 18(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Martins et al. (2018)	imex:IM-28469|pubmed:29476059	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26439741|imex:IM-28469-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSRNOG00000016271(gene)|ensembl:ENSRNOT00000023037(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001540"(amyloid-beta binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0010008"(endosome membrane)|go:"GO:0030660"(Golgi-associated vesicle membrane)|go:"GO:0031301"(integral component of organelle membrane)|go:"GO:0042985"(negative regulation of amyloid precursor protein biosynthetic process)|interpro:IPR007084(BRICHOS)|interpro:IPR040145|mint:Q5XIE8|refseq:NP_001006964.1|rgd:620727	ensembl:ENSRNOG00000042731(gene)|ensembl:ENSRNOT00000015560(transcript)|go:"GO:0005313"(L-glutamate transmembrane transporter activity)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0015183"(L-aspartate transmembrane transporter activity)|go:"GO:0015293"(symporter activity)|go:"GO:0015810"(aspartate transmembrane transport)|go:"GO:0015813"(L-glutamate transmembrane transport)|go:"GO:0016021"(integral component of membrane)|go:"GO:0022857"(transmembrane transporter activity)|go:"GO:0043490"(malate-aspartate shuttle)|interpro:IPR002067(Mitochondrial carrier protein)|interpro:IPR018108|interpro:IPR023395|mint:Q505J6|reactome:R-RNO-428643|refseq:NP_001037745.2|rgd:1590470	-	-	-	figure legend:st1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10116(rat-brain-cortex)|taxid:10116(Rattus norvegicus brain cortex)	-	2020/10/30	2020/10/30	rogid:DtE+ZXAZKdCMvUW5K+jXQ5bH07M10116	rogid:q/V+Yj/8pYnmEvmxNLaSV+6o3J010116	rigid:3wclwrjZRvafcOruQOYnegkn54c	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q5XIE8	uniprotkb:P15146	intact:EBI-15348306|ensembl:ENSRNOP00000023037	intact:EBI-6095638	psi-mi:itm2b_rat(display_long)|uniprotkb:Itm2b(gene name)|psi-mi:Itm2b(display_short)|uniprotkb:Immature BRI2(gene name synonym)|uniprotkb:Transmembrane protein BRI(gene name synonym)	psi-mi:mtap2_rat(display_long)|uniprotkb:Map2(gene name)|psi-mi:Map2(display_short)|uniprotkb:Mtap2(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Martins et al. (2018)	imex:IM-28469|pubmed:29476059	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26439741|imex:IM-28469-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSRNOG00000016271(gene)|ensembl:ENSRNOT00000023037(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001540"(amyloid-beta binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0010008"(endosome membrane)|go:"GO:0030660"(Golgi-associated vesicle membrane)|go:"GO:0031301"(integral component of organelle membrane)|go:"GO:0042985"(negative regulation of amyloid precursor protein biosynthetic process)|interpro:IPR007084(BRICHOS)|interpro:IPR040145|mint:Q5XIE8|refseq:NP_001006964.1|rgd:620727	interpro:IPR030797|refseq:XP_008765430.1|mint:P15146|rgd:3044|interpro:IPR013588(MAP2/Tau projection)|interpro:IPR001084(Tubulin-binding Tau protein)|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0001578"(microtubule bundle formation)|go:"GO:0002162"(dystroglycan binding)|go:"GO:0003779"(actin binding)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005790"(smooth endoplasmic reticulum)|go:"GO:0005791"(rough endoplasmic reticulum)|go:"GO:0005874"(microtubule)|go:"GO:0007026"(negative regulation of microtubule depolymerization)|go:"GO:0007409"(axonogenesis)|go:"GO:0008017"(microtubule binding)|go:"GO:0014069"(postsynaptic density)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0016358"(dendrite development)|go:"GO:0019901"(protein kinase binding)|go:"GO:0021954"(central nervous system neuron development)|go:"GO:0030010"(establishment of cell polarity)|go:"GO:0030424"(axon)|go:"GO:0030425"(dendrite)|go:"GO:0030517"(negative regulation of axon extension)|go:"GO:0031115"(negative regulation of microtubule polymerization)|go:"GO:0031175"(neuron projection development)|go:"GO:0032355"(response to estradiol)|go:"GO:0032570"(response to progesterone)|go:"GO:0032587"(ruffle membrane)|go:"GO:0032839"(dendrite cytoplasm)|go:"GO:0032991"(protein-containing complex)|go:"GO:0043005"(neuron projection)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043194"(axon initial segment)|go:"GO:0043198"(dendritic shaft)|go:"GO:0043203"(axon hillock)|go:"GO:0044294"(dendritic growth cone)|go:"GO:0044297"(cell body)|go:"GO:0044307"(dendritic branch)|go:"GO:0048813"(dendrite morphogenesis)|go:"GO:0071310"(cellular response to organic substance)|go:"GO:0097440"(apical dendrite)|go:"GO:0097441"(basal dendrite)|go:"GO:0097442"(CA3 pyramidal cell dendrite)|go:"GO:0150001"(primary dendrite)|go:"GO:0150002"(distal dendrite)|go:"GO:0150014"(apical distal dendrite)|go:"GO:1901953"(positive regulation of anterograde dense core granule transport)|go:"GO:1902513"(regulation of organelle transport along microtubule)|go:"GO:1902737"(dendritic filopodium)|go:"GO:1903744"(positive regulation of anterograde synaptic vesicle transport)|go:"GO:1903827"|go:"GO:1904527"(negative regulation of microtubule binding)|go:"GO:1990635"(proximal dendrite)|go:"GO:1990769"(proximal neuron projection)|go:"GO:2000575"(obsolete negative regulation of microtubule motor activity)|go:"GO:0034399"(nuclear periphery)	-	-	-	figure legend:st1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10116(rat-brain-cortex)|taxid:10116(Rattus norvegicus brain cortex)	-	2020/10/30	2020/10/30	rogid:DtE+ZXAZKdCMvUW5K+jXQ5bH07M10116	rogid:idoGPInRds+FBHZ23KyNC+c5gL810116	rigid:3wclwrjZRvafcOruQOYnegkn54c	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q5XIE8	uniprotkb:Q5XI51	intact:EBI-15348306|ensembl:ENSRNOP00000023037	intact:EBI-26438734|ensembl:ENSRNOP00000003421	psi-mi:itm2b_rat(display_long)|uniprotkb:Itm2b(gene name)|psi-mi:Itm2b(display_short)|uniprotkb:Immature BRI2(gene name synonym)|uniprotkb:Transmembrane protein BRI(gene name synonym)	psi-mi:kif2b_rat(display_long)|uniprotkb:Kif2b(gene name)|psi-mi:Kif2b(display_short)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Martins et al. (2018)	imex:IM-28469|pubmed:29476059	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26439741|imex:IM-28469-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSRNOG00000016271(gene)|ensembl:ENSRNOT00000023037(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001540"(amyloid-beta binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0010008"(endosome membrane)|go:"GO:0030660"(Golgi-associated vesicle membrane)|go:"GO:0031301"(integral component of organelle membrane)|go:"GO:0042985"(negative regulation of amyloid precursor protein biosynthetic process)|interpro:IPR007084(BRICHOS)|interpro:IPR040145|mint:Q5XIE8|refseq:NP_001006964.1|rgd:620727	go:"GO:0045171"(intercellular bridge)|go:"GO:0051301"(cell division)|go:"GO:0051310"(metaphase plate congression)|go:"GO:0051983"(regulation of chromosome segregation)|go:"GO:0072686"(mitotic spindle)|go:"GO:1990939"|interpro:IPR001752(Kinesin, motor region)|interpro:IPR019821|interpro:IPR027417|interpro:IPR027640|interpro:IPR036961|mint:Q5XI51|reactome:R-RNO-141444|reactome:R-RNO-2132295|reactome:R-RNO-2467813|reactome:R-RNO-2500257|reactome:R-RNO-5663220|reactome:R-RNO-6811434|reactome:R-RNO-68877|reactome:R-RNO-9648025|reactome:R-RNO-983189|go:"GO:0008017"(microtubule binding)|ensembl:ENSRNOG00000002535(gene)|ensembl:ENSRNOT00000003421(transcript)|go:"GO:0000776"(kinetochore)|go:"GO:0003777"(microtubule motor activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005819"(spindle)|go:"GO:0005871"(kinesin complex)|go:"GO:0005874"(microtubule)|go:"GO:0007018"(microtubule-based movement)|go:"GO:0007019"(microtubule depolymerization)|refseq:NP_001005874.2|rgd:1359248	-	-	-	figure legend:st1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10116(rat-brain-cortex)|taxid:10116(Rattus norvegicus brain cortex)	-	2020/10/30	2020/10/30	rogid:DtE+ZXAZKdCMvUW5K+jXQ5bH07M10116	rogid:9u++O43iiRXdO/DQUBybFFJmfMU10116	rigid:3wclwrjZRvafcOruQOYnegkn54c	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q5XIE8	uniprotkb:P56574	intact:EBI-15348306|ensembl:ENSRNOP00000023037	intact:EBI-920942|uniprotkb:Q6DGF1|ensembl:ENSRNOP00000019059	psi-mi:itm2b_rat(display_long)|uniprotkb:Itm2b(gene name)|psi-mi:Itm2b(display_short)|uniprotkb:Immature BRI2(gene name synonym)|uniprotkb:Transmembrane protein BRI(gene name synonym)	psi-mi:idhp_rat(display_long)|uniprotkb:Idh2(gene name)|psi-mi:Idh2(display_short)|uniprotkb:Oxalosuccinate decarboxylase(gene name synonym)|uniprotkb:"NADP(+)-specific ICDH"(gene name synonym)|uniprotkb:IDP(gene name synonym)|uniprotkb:ICD-M(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Martins et al. (2018)	imex:IM-28469|pubmed:29476059	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26439741|imex:IM-28469-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSRNOG00000016271(gene)|ensembl:ENSRNOT00000023037(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001540"(amyloid-beta binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0010008"(endosome membrane)|go:"GO:0030660"(Golgi-associated vesicle membrane)|go:"GO:0031301"(integral component of organelle membrane)|go:"GO:0042985"(negative regulation of amyloid precursor protein biosynthetic process)|interpro:IPR007084(BRICHOS)|interpro:IPR040145|mint:Q5XIE8|refseq:NP_001006964.1|rgd:620727	rgd:1597139|refseq:NP_001014183.1|ensembl:ENSRNOG00000013949(gene)|ensembl:ENSRNOT00000019059(transcript)|go:"GO:0000287"(magnesium ion binding)|go:"GO:0004448"(isocitrate dehydrogenase activity)|go:"GO:0004450"("isocitrate dehydrogenase (NADP+) activity")|go:"GO:0005739"(mitochondrion)|go:"GO:0005777"(peroxisome)|go:"GO:0005829"(cytosol)|go:"GO:0006097"(glyoxylate cycle)|go:"GO:0006099"(tricarboxylic acid cycle)|go:"GO:0006102"(isocitrate metabolic process)|go:"GO:0006103"(2-oxoglutarate metabolic process)|go:"GO:0006739"(NADP metabolic process)|go:"GO:0006741"(NADP biosynthetic process)|go:"GO:0051287"(NAD binding)|go:"GO:0060253"(negative regulation of glial cell proliferation)|go:"GO:1903976"(negative regulation of glial cell migration)|go:"GO:1904465"(negative regulation of matrix metallopeptidase secretion)|interpro:IPR004790(Isocitrate dehydrogenase NADP-dependent, eukaryotic)|interpro:IPR019818|interpro:IPR024084|mint:P56574|reactome:R-RNO-2151201|reactome:R-RNO-71403	-	-	-	figure legend:st1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10116(rat-brain-cortex)|taxid:10116(Rattus norvegicus brain cortex)	-	2020/10/30	2020/10/30	rogid:DtE+ZXAZKdCMvUW5K+jXQ5bH07M10116	rogid:CGI/bMOGAnNsRs5goqGEWMPqPp010116	rigid:3wclwrjZRvafcOruQOYnegkn54c	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q5XIE8	uniprotkb:Q9Z214	intact:EBI-15348306|ensembl:ENSRNOP00000023037	intact:EBI-2338940|uniprotkb:O08567|uniprotkb:O88800|uniprotkb:Q9QUJ8|uniprotkb:Q9QWN5	psi-mi:itm2b_rat(display_long)|uniprotkb:Itm2b(gene name)|psi-mi:Itm2b(display_short)|uniprotkb:Immature BRI2(gene name synonym)|uniprotkb:Transmembrane protein BRI(gene name synonym)	psi-mi:home1_rat(display_long)|uniprotkb:Homer1(gene name)|psi-mi:Homer1(display_short)|uniprotkb:Homer(gene name synonym)|uniprotkb:Vesl(gene name synonym)|uniprotkb:PSD-Zip45(gene name synonym)|uniprotkb:VASP/Ena-related gene up-regulated during seizure and LTP 1(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Martins et al. (2018)	imex:IM-28469|pubmed:29476059	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26439741|imex:IM-28469-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSRNOG00000016271(gene)|ensembl:ENSRNOT00000023037(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001540"(amyloid-beta binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0010008"(endosome membrane)|go:"GO:0030660"(Golgi-associated vesicle membrane)|go:"GO:0031301"(integral component of organelle membrane)|go:"GO:0042985"(negative regulation of amyloid precursor protein biosynthetic process)|interpro:IPR007084(BRICHOS)|interpro:IPR040145|mint:Q5XIE8|refseq:NP_001006964.1|rgd:620727	rgd:628725|refseq:NP_113895.1|interpro:IPR000697(EVH1)|interpro:IPR011993(Pleckstrin homology-type)|refseq:XP_006231837.1|mint:Q9Z214|interpro:IPR044100|go:"GO:0003009"(skeletal muscle contraction)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0007216"(G protein-coupled glutamate receptor signaling pathway)|go:"GO:0007623"(circadian rhythm)|go:"GO:0014069"(postsynaptic density)|go:"GO:0016020"(membrane)|go:"GO:0030018"(Z disc)|go:"GO:0030424"(axon)|go:"GO:0030425"(dendrite)|go:"GO:0031802"(type 5 metabotropic glutamate receptor binding)|go:"GO:0035094"(response to nicotine)|go:"GO:0035256"(G protein-coupled glutamate receptor binding)|go:"GO:0035418"(protein localization to synapse)|go:"GO:0042220"(response to cocaine)|go:"GO:0042802"(identical protein binding)|go:"GO:0043005"(neuron projection)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043034"(costamere)|go:"GO:0043197"(dendritic spine)|go:"GO:0043198"(dendritic shaft)|go:"GO:0044309"(neuron spine)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045177"(apical part of cell)|go:"GO:0045202"(synapse)|go:"GO:0048148"(behavioral response to cocaine)|go:"GO:0048741"(skeletal muscle fiber development)|go:"GO:0048875"(chemical homeostasis within a tissue)|go:"GO:0051262"(protein tetramerization)|go:"GO:0051592"(response to calcium ion)|go:"GO:0051928"(positive regulation of calcium ion transport)|go:"GO:0051966"(regulation of synaptic transmission, glutamatergic)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0090279"(regulation of calcium ion import)|go:"GO:0097110"(scaffold protein binding)|go:"GO:0098794"(postsynapse)|go:"GO:0098962"(regulation of postsynaptic neurotransmitter receptor activity)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099186"(structural constituent of postsynapse)|go:"GO:0099524"(postsynaptic cytosol)|go:"GO:1902950"(regulation of dendritic spine maintenance)|go:"GO:2001256"(regulation of store-operated calcium entry)|go:"GO:2001257"(regulation of cation channel activity)|rcsb pdb:1DDV|rcsb pdb:1DDW|rcsb pdb:1I2H|rcsb pdb:3CVE|reactome:R-RNO-6794361	-	-	-	figure legend:st1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10116(rat-brain-cortex)|taxid:10116(Rattus norvegicus brain cortex)	-	2020/10/30	2020/10/30	rogid:DtE+ZXAZKdCMvUW5K+jXQ5bH07M10116	rogid:7yzSvJnto6+5zXH000SPZOIYe3w10116	rigid:3wclwrjZRvafcOruQOYnegkn54c	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q5XIE8	uniprotkb:Q8VHV7	intact:EBI-15348306|ensembl:ENSRNOP00000023037	intact:EBI-919615|uniprotkb:A1L1J1	psi-mi:itm2b_rat(display_long)|uniprotkb:Itm2b(gene name)|psi-mi:Itm2b(display_short)|uniprotkb:Immature BRI2(gene name synonym)|uniprotkb:Transmembrane protein BRI(gene name synonym)	psi-mi:hnrh1_rat(display_long)|uniprotkb:Hnrnph1(gene name)|psi-mi:Hnrnph1(display_short)|uniprotkb:Ratsg1(gene name synonym)|uniprotkb:Hnrph1(gene name synonym)|uniprotkb:Hnrph(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Martins et al. (2018)	imex:IM-28469|pubmed:29476059	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26439741|imex:IM-28469-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSRNOG00000016271(gene)|ensembl:ENSRNOT00000023037(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001540"(amyloid-beta binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0010008"(endosome membrane)|go:"GO:0030660"(Golgi-associated vesicle membrane)|go:"GO:0031301"(integral component of organelle membrane)|go:"GO:0042985"(negative regulation of amyloid precursor protein biosynthetic process)|interpro:IPR007084(BRICHOS)|interpro:IPR040145|mint:Q5XIE8|refseq:NP_001006964.1|rgd:620727	rgd:620840|refseq:NP_543172.1|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR012996(Zinc finger, CHHC-type)|mint:Q8VHV7|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR035979|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006396"(RNA processing)|go:"GO:0006397"(mRNA processing)|go:"GO:0008380"(RNA splicing)|go:"GO:0014069"(postsynaptic density)|go:"GO:0019899"(enzyme binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0043484"(regulation of RNA splicing)|go:"GO:0071013"(catalytic step 2 spliceosome)|go:"GO:0098761"(cellular response to interleukin-7)|go:"GO:1901653"(cellular response to peptide)|go:"GO:1990904"(ribonucleoprotein complex)|reactome:R-RNO-6803529|reactome:R-RNO-72163	-	-	-	figure legend:st1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10116(rat-brain-cortex)|taxid:10116(Rattus norvegicus brain cortex)	-	2020/10/30	2020/10/30	rogid:DtE+ZXAZKdCMvUW5K+jXQ5bH07M10116	rogid:afNAvozo2+6P9UdVJw/giQXs4QA10116	rigid:3wclwrjZRvafcOruQOYnegkn54c	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q5XIE8	uniprotkb:P63018	intact:EBI-15348306|ensembl:ENSRNOP00000023037	intact:EBI-433431|uniprotkb:P08109|uniprotkb:P12225|uniprotkb:Q4FZY7|uniprotkb:Q62373|uniprotkb:Q62374|uniprotkb:Q62375	psi-mi:itm2b_rat(display_long)|uniprotkb:Itm2b(gene name)|psi-mi:Itm2b(display_short)|uniprotkb:Immature BRI2(gene name synonym)|uniprotkb:Transmembrane protein BRI(gene name synonym)	psi-mi:hsp7c_rat(display_long)|uniprotkb:Hspa8(gene name)|psi-mi:Hspa8(display_short)|uniprotkb:Hsc70(gene name synonym)|uniprotkb:Heat shock 70 kDa protein 8(gene name synonym)|uniprotkb:Hsc73(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Martins et al. (2018)	imex:IM-28469|pubmed:29476059	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26439741|imex:IM-28469-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSRNOG00000016271(gene)|ensembl:ENSRNOT00000023037(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001540"(amyloid-beta binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0010008"(endosome membrane)|go:"GO:0030660"(Golgi-associated vesicle membrane)|go:"GO:0031301"(integral component of organelle membrane)|go:"GO:0042985"(negative regulation of amyloid precursor protein biosynthetic process)|interpro:IPR007084(BRICHOS)|interpro:IPR040145|mint:Q5XIE8|refseq:NP_001006964.1|rgd:620727	rgd:621725|refseq:NP_077327.1|go:"GO:0000082"(G1/S transition of mitotic cell cycle)|go:"GO:0000974"(Prp19 complex)|go:"GO:0001664"(G protein-coupled receptor binding)|go:"GO:0001786"(phosphatidylserine binding)|go:"GO:0001822"(kidney development)|go:"GO:0001916"(positive regulation of T cell mediated cytotoxicity)|go:"GO:0001917"(photoreceptor inner segment)|go:"GO:0003723"(RNA binding)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005681"(spliceosomal complex)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005764"(lysosome)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005770"(late endosome)|go:"GO:0005776"(autophagosome)|go:"GO:0005829"(cytosol)|go:"GO:0005874"(microtubule)|go:"GO:0005882"(intermediate filament)|go:"GO:0005886"(plasma membrane)|go:"GO:0006397"(mRNA processing)|go:"GO:0006457"(protein folding)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0007519"(skeletal muscle tissue development)|go:"GO:0007568"(aging)|go:"GO:0007608"(sensory perception of smell)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0008088"(axo-dendritic transport)|go:"GO:0008380"(RNA splicing)|go:"GO:0009408"(response to heat)|go:"GO:0009986"(cell surface)|go:"GO:0010045"(response to nickel cation)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010667"(negative regulation of cardiac muscle cell apoptotic process)|go:"GO:0014069"(postsynaptic density)|go:"GO:0014823"(response to activity)|go:"GO:0016191"(synaptic vesicle uncoating)|go:"GO:0016192"(vesicle-mediated transport)|go:"GO:0019899"(enzyme binding)|go:"GO:0021549"(cerebellum development)|go:"GO:0030424"(axon)|go:"GO:0030425"(dendrite)|go:"GO:0030674"(protein-macromolecule adaptor activity)|go:"GO:0030900"(forebrain development)|go:"GO:0031072"(heat shock protein binding)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0031647"(regulation of protein stability)|go:"GO:0031686"(A1 adenosine receptor binding)|go:"GO:0032279"(asymmetric synapse)|go:"GO:0032355"(response to estradiol)|go:"GO:0032570"(response to progesterone)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034605"(cellular response to heat)|go:"GO:0034620"(cellular response to unfolded protein)|go:"GO:0042026"(protein refolding)|go:"GO:0042277"(peptide binding)|go:"GO:0042470"(melanosome)|go:"GO:0042493"|go:"GO:0042594"(response to starvation)|go:"GO:0043005"(neuron projection)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043085"(positive regulation of catalytic activity)|go:"GO:0043195"(terminal bouton)|go:"GO:0043197"(dendritic spine)|go:"GO:0043198"(dendritic shaft)|go:"GO:0043202"(lysosomal lumen)|go:"GO:0043204"(perikaryon)|go:"GO:0043531"(ADP binding)|go:"GO:0043624"|go:"GO:0044183"(protein folding chaperone)|go:"GO:0044309"(neuron spine)|go:"GO:0044743"(protein transmembrane import into intracellular organelle)|go:"GO:0044788"(modulation by host of viral process)|go:"GO:0044829"(positive regulation by host of viral genome replication)|go:"GO:0045121"(membrane raft)|go:"GO:0045471"(response to ethanol)|go:"GO:0045862"(positive regulation of proteolysis)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0046034"(ATP metabolic process)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0048026"(positive regulation of mRNA splicing, via spliceosome)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0050766"(positive regulation of phagocytosis)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0051085"(chaperone cofactor-dependent protein refolding)|go:"GO:0051087"(chaperone binding)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0051787"(misfolded protein binding)|go:"GO:0055131"(C3HC4-type RING finger domain binding)|go:"GO:0061077"(chaperone-mediated protein folding)|go:"GO:0061635"(regulation of protein complex stability)|go:"GO:0061684"(chaperone-mediated autophagy)|go:"GO:0061738"(late endosomal microautophagy)|go:"GO:0061740"(protein targeting to lysosome involved in chaperone-mediated autophagy)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071276"(cellular response to cadmium ion)|go:"GO:0072318"(clathrin coat disassembly)|go:"GO:0097214"(positive regulation of lysosomal membrane permeability)|go:"GO:0044849"(estrous cycle)|go:"GO:0098684"(photoreceptor ribbon synapse)|go:"GO:0098690"(glycinergic synapse)|go:"GO:0098793"(presynapse)|go:"GO:0098794"(postsynapse)|go:"GO:0098880"(maintenance of postsynaptic specialization structure)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099175"(regulation of postsynapse organization)|go:"GO:0099523"(presynaptic cytosol)|go:"GO:0099524"(postsynaptic cytosol)|go:"GO:0099634"(postsynaptic specialization membrane)|go:"GO:0101031"(chaperone complex)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|go:"GO:1902904"(negative regulation of supramolecular fiber organization)|go:"GO:1903206"(negative regulation of hydrogen peroxide-induced cell death)|go:"GO:1904592"(positive regulation of protein refolding)|go:"GO:1904593"(prostaglandin binding)|go:"GO:1904764"(chaperone-mediated autophagy translocation complex disassembly)|go:"GO:1990124"(messenger ribonucleoprotein complex)|go:"GO:1990832"(slow axonal transport)|go:"GO:1990833"(clathrin-uncoating ATPase activity)|go:"GO:1990834"(response to odorant)|go:"GO:1990836"(lysosomal matrix)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR013126(Heat shock protein 70)|interpro:IPR018181|interpro:IPR029047|interpro:IPR029048|interpro:IPR043129|rcsb pdb:1CKR|rcsb pdb:1Q2G|rcsb pdb:1UD0|rcsb pdb:2V7Z|rcsb pdb:7HSC|mint:P63018|dip:DIP-33262N	-	-	-	figure legend:st1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10116(rat-brain-cortex)|taxid:10116(Rattus norvegicus brain cortex)	-	2020/10/30	2020/10/30	rogid:DtE+ZXAZKdCMvUW5K+jXQ5bH07M10116	rogid:WDnUczLfoe3ODQbiEITN3DfQnFA10116	rigid:3wclwrjZRvafcOruQOYnegkn54c	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q5XIE8	uniprotkb:P55063	intact:EBI-15348306|ensembl:ENSRNOP00000023037	intact:EBI-918863|uniprotkb:Q32P36|uniprotkb:Q6MG67|ensembl:ENSRNOP00000063974	psi-mi:itm2b_rat(display_long)|uniprotkb:Itm2b(gene name)|psi-mi:Itm2b(display_short)|uniprotkb:Immature BRI2(gene name synonym)|uniprotkb:Transmembrane protein BRI(gene name synonym)	psi-mi:hs71l_rat(display_long)|uniprotkb:Heat shock 70 kDa protein 3(gene name synonym)|uniprotkb:Hspa1l(gene name)|psi-mi:Hspa1l(display_short)|uniprotkb:Hsp70-3(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Martins et al. (2018)	imex:IM-28469|pubmed:29476059	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26439741|imex:IM-28469-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSRNOG00000016271(gene)|ensembl:ENSRNOT00000023037(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001540"(amyloid-beta binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0010008"(endosome membrane)|go:"GO:0030660"(Golgi-associated vesicle membrane)|go:"GO:0031301"(integral component of organelle membrane)|go:"GO:0042985"(negative regulation of amyloid precursor protein biosynthetic process)|interpro:IPR007084(BRICHOS)|interpro:IPR040145|mint:Q5XIE8|refseq:NP_001006964.1|rgd:620727	rgd:1595925|refseq:NP_997711.1|refseq:XP_017457033.1|ensembl:ENSRNOG00000047966(gene)|ensembl:ENSRNOT00000074223(transcript)|go:"GO:0002199"(zona pellucida receptor complex)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0007339"(binding of sperm to zona pellucida)|go:"GO:0016192"(vesicle-mediated transport)|go:"GO:0031072"(heat shock protein binding)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0034620"(cellular response to unfolded protein)|go:"GO:0042026"(protein refolding)|go:"GO:0044183"(protein folding chaperone)|go:"GO:0044297"(cell body)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0051085"(chaperone cofactor-dependent protein refolding)|go:"GO:0051787"(misfolded protein binding)|go:"GO:1903955"(positive regulation of protein targeting to mitochondrion)|interpro:IPR013126(Heat shock protein 70)|interpro:IPR018181|interpro:IPR029047|interpro:IPR029048|interpro:IPR043129|mint:P55063|reactome:R-RNO-3371453|reactome:R-RNO-3371497|reactome:R-RNO-3371568|reactome:R-RNO-3371571	-	-	-	figure legend:st1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10116(rat-brain-cortex)|taxid:10116(Rattus norvegicus brain cortex)	-	2020/10/30	2020/10/30	rogid:DtE+ZXAZKdCMvUW5K+jXQ5bH07M10116	rogid:jBu6RUqH2VpyJdBAuEXR+R1oe1w10116	rigid:3wclwrjZRvafcOruQOYnegkn54c	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q5XIE8	uniprotkb:P52287	intact:EBI-15348306|ensembl:ENSRNOP00000023037	intact:EBI-26438681|ensembl:ENSRNOP00000069551|ensembl:ENSRNOP00000021480	psi-mi:itm2b_rat(display_long)|uniprotkb:Itm2b(gene name)|psi-mi:Itm2b(display_short)|uniprotkb:Immature BRI2(gene name synonym)|uniprotkb:Transmembrane protein BRI(gene name synonym)	psi-mi:gbb3_rat(display_long)|uniprotkb:Gnb3(gene name)|psi-mi:Gnb3(display_short)|uniprotkb:Transducin beta chain 3(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Martins et al. (2018)	imex:IM-28469|pubmed:29476059	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26439741|imex:IM-28469-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSRNOG00000016271(gene)|ensembl:ENSRNOT00000023037(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001540"(amyloid-beta binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0010008"(endosome membrane)|go:"GO:0030660"(Golgi-associated vesicle membrane)|go:"GO:0031301"(integral component of organelle membrane)|go:"GO:0042985"(negative regulation of amyloid precursor protein biosynthetic process)|interpro:IPR007084(BRICHOS)|interpro:IPR040145|mint:Q5XIE8|refseq:NP_001006964.1|rgd:620727	ensembl:ENSRNOG00000015541(gene)|ensembl:ENSRNOT00000021481(transcript)|ensembl:ENSRNOT00000090898(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0005834"(heterotrimeric G-protein complex)|go:"GO:0006884"(cell volume homeostasis)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0010906"(regulation of glucose metabolic process)|go:"GO:0030425"(dendrite)|go:"GO:0030507"(spectrin binding)|go:"GO:0031682"(G-protein gamma-subunit binding)|go:"GO:0032350"(regulation of hormone metabolic process)|go:"GO:0043005"(neuron projection)|go:"GO:0044297"(cell body)|go:"GO:0045598"(regulation of fat cell differentiation)|go:"GO:0051020"(GTPase binding)|go:"GO:0090181"(regulation of cholesterol metabolic process)|go:"GO:0090207"(regulation of triglyceride metabolic process)|go:"GO:1903725"(regulation of phospholipid metabolic process)|interpro:IPR001632(G-protein, beta subunit)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR016346(Guanine nucleotide-binding protein, beta subunit)|interpro:IPR019775|interpro:IPR020472|interpro:IPR036322|mint:P52287|reactome:R-RNO-1296041|reactome:R-RNO-202040|reactome:R-RNO-381676|reactome:R-RNO-381771|reactome:R-RNO-392170|reactome:R-RNO-392451|reactome:R-RNO-400042|reactome:R-RNO-4086398|reactome:R-RNO-416476|reactome:R-RNO-418594|reactome:R-RNO-418597|reactome:R-RNO-420092|reactome:R-RNO-428930|reactome:R-RNO-432040|reactome:R-RNO-456926|reactome:R-RNO-6814122|reactome:R-RNO-8964616|reactome:R-RNO-997272|refseq:NP_068630.1|rgd:708344	-	-	-	figure legend:st1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10116(rat-brain-cortex)|taxid:10116(Rattus norvegicus brain cortex)	-	2020/10/30	2020/10/30	rogid:DtE+ZXAZKdCMvUW5K+jXQ5bH07M10116	rogid:VcVBQpWvLdQlT9xuUU/SL2mMPaI10116	rigid:3wclwrjZRvafcOruQOYnegkn54c	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q5XIE8	uniprotkb:P63095	intact:EBI-15348306|ensembl:ENSRNOP00000023037	intact:EBI-444717|uniprotkb:P04894|uniprotkb:P08755|uniprotkb:Q05087|uniprotkb:Q45QM7|uniprotkb:Q9Z1R8	psi-mi:itm2b_rat(display_long)|uniprotkb:Itm2b(gene name)|psi-mi:Itm2b(display_short)|uniprotkb:Immature BRI2(gene name synonym)|uniprotkb:Transmembrane protein BRI(gene name synonym)	psi-mi:gnas2_rat(display_long)|uniprotkb:Adenylate cyclase-stimulating G alpha protein(gene name synonym)|uniprotkb:G-alpha-8(gene name synonym)|uniprotkb:Gnas(gene name)|psi-mi:Gnas(display_short)|uniprotkb:Gnas1(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Martins et al. (2018)	imex:IM-28469|pubmed:29476059	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26439741|imex:IM-28469-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSRNOG00000016271(gene)|ensembl:ENSRNOT00000023037(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001540"(amyloid-beta binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0010008"(endosome membrane)|go:"GO:0030660"(Golgi-associated vesicle membrane)|go:"GO:0031301"(integral component of organelle membrane)|go:"GO:0042985"(negative regulation of amyloid precursor protein biosynthetic process)|interpro:IPR007084(BRICHOS)|interpro:IPR040145|mint:Q5XIE8|refseq:NP_001006964.1|rgd:620727	rgd:2716|refseq:NP_062005.1|interpro:IPR000367(G-protein alpha subunit, group S)|interpro:IPR001019("Guanine nucleotide binding protein (G-protein), alpha subunit")|interpro:IPR011025(G protein alpha subunit, helical insertion)|go:"GO:0001501"(skeletal system development)|go:"GO:0001664"(G protein-coupled receptor binding)|go:"GO:0001726"(ruffle)|go:"GO:0001894"(tissue homeostasis)|go:"GO:0001934"(positive regulation of protein phosphorylation)|go:"GO:0001958"(endochondral ossification)|go:"GO:0001965"(G-protein alpha-subunit binding)|go:"GO:0003924"(GTPase activity)|go:"GO:0005159"(insulin-like growth factor receptor binding)|go:"GO:0005525"(GTP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005829"(cytosol)|go:"GO:0005834"(heterotrimeric G-protein complex)|go:"GO:0005886"(plasma membrane)|go:"GO:0006112"(energy reserve metabolic process)|go:"GO:0006306"(DNA methylation)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0071380"(cellular response to prostaglandin E stimulus)|go:"GO:0071514"(genomic imprinting)|go:"GO:0071870"(cellular response to catecholamine stimulus)|go:"GO:0071880"(adenylate cyclase-activating adrenergic receptor signaling pathway)|go:"GO:0120162"(positive regulation of cold-induced thermogenesis)|go:"GO:2000828"(regulation of parathyroid hormone secretion)|go:"GO:0007188"(adenylate cyclase-modulating G protein-coupled receptor signaling pathway)|go:"GO:0007189"(adenylate cyclase-activating G protein-coupled receptor signaling pathway)|go:"GO:0007191"(adenylate cyclase-activating dopamine receptor signaling pathway)|go:"GO:0007606"(sensory perception of chemical stimulus)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0009791"(post-embryonic development)|go:"GO:0010765"(positive regulation of sodium ion transport)|go:"GO:0010856"(adenylate cyclase activator activity)|go:"GO:0016020"(membrane)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030142"(COPI-coated Golgi to ER transport vesicle)|go:"GO:0030425"(dendrite)|go:"GO:0031681"(G-protein beta-subunit binding)|go:"GO:0031683"(G-protein beta/gamma-subunit complex binding)|go:"GO:0031698"(beta-2 adrenergic receptor binding)|go:"GO:0031748"(D1 dopamine receptor binding)|go:"GO:0031852"(mu-type opioid receptor binding)|go:"GO:0035116"(embryonic hindlimb morphogenesis)|go:"GO:0035255"(ionotropic glutamate receptor binding)|go:"GO:0035264"(multicellular organism growth)|go:"GO:0035814"(negative regulation of renal sodium excretion)|go:"GO:0040015"(negative regulation of multicellular organism growth)|go:"GO:0040032"(post-embryonic body morphogenesis)|go:"GO:0042493"|go:"GO:0043014"(alpha-tubulin binding)|go:"GO:0043025"(neuronal cell body)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0043547"(positive regulation of GTPase activity)|go:"GO:0043588"(skin development)|go:"GO:0043950"(positive regulation of cAMP-mediated signaling)|go:"GO:0045121"(membrane raft)|go:"GO:0045669"(positive regulation of osteoblast differentiation)|go:"GO:0045672"(positive regulation of osteoclast differentiation)|go:"GO:0045776"(negative regulation of blood pressure)|go:"GO:0046872"(metal ion binding)|go:"GO:0047391"(alkylglycerophosphoethanolamine phosphodiesterase activity)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0048589"(developmental growth)|go:"GO:0048701"(embryonic cranial skeleton morphogenesis)|go:"GO:0051216"(cartilage development)|go:"GO:0051430"(corticotropin-releasing hormone receptor 1 binding)|go:"GO:0055037"(recycling endosome)|go:"GO:0055074"(calcium ion homeostasis)|go:"GO:0060348"(bone development)|go:"GO:0070527"(platelet aggregation)|interpro:IPR027417|mint:P63095	-	-	-	figure legend:st1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10116(rat-brain-cortex)|taxid:10116(Rattus norvegicus brain cortex)	-	2020/10/30	2020/10/30	rogid:DtE+ZXAZKdCMvUW5K+jXQ5bH07M10116	rogid:1yRRwUpxAu++bhy6TZHaOWy3Tdw10116	rigid:3wclwrjZRvafcOruQOYnegkn54c	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q5XIE8	uniprotkb:P43425	intact:EBI-15348306|ensembl:ENSRNOP00000023037	intact:EBI-26438644|uniprotkb:Q45QK4	psi-mi:itm2b_rat(display_long)|uniprotkb:Itm2b(gene name)|psi-mi:Itm2b(display_short)|uniprotkb:Immature BRI2(gene name synonym)|uniprotkb:Transmembrane protein BRI(gene name synonym)	psi-mi:gbg7_rat(display_long)|uniprotkb:Gng7(gene name)|psi-mi:Gng7(display_short)|uniprotkb:Gngt7(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Martins et al. (2018)	imex:IM-28469|pubmed:29476059	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26439741|imex:IM-28469-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSRNOG00000016271(gene)|ensembl:ENSRNOT00000023037(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001540"(amyloid-beta binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0010008"(endosome membrane)|go:"GO:0030660"(Golgi-associated vesicle membrane)|go:"GO:0031301"(integral component of organelle membrane)|go:"GO:0042985"(negative regulation of amyloid precursor protein biosynthetic process)|interpro:IPR007084(BRICHOS)|interpro:IPR040145|mint:Q5XIE8|refseq:NP_001006964.1|rgd:620727	reactome:R-RNO-418594|reactome:R-RNO-418597|reactome:R-RNO-420092|reactome:R-RNO-428930|reactome:R-RNO-432040|reactome:R-RNO-456926|reactome:R-RNO-8964616|reactome:R-RNO-997272|go:"GO:0001662"(behavioral fear response)|go:"GO:0005834"(heterotrimeric G-protein complex)|go:"GO:0007168"(receptor guanylyl cyclase signaling pathway)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0007626"(locomotory behavior)|go:"GO:0031680"(G-protein beta/gamma-subunit complex)|go:"GO:0031681"(G-protein beta-subunit binding)|go:"GO:0045761"(regulation of adenylate cyclase activity)|reactome:R-RNO-1296041|reactome:R-RNO-202040|reactome:R-RNO-381676|reactome:R-RNO-392170|reactome:R-RNO-392451|reactome:R-RNO-400042|reactome:R-RNO-4086398|reactome:R-RNO-416476|mint:P43425|refseq:NP_077052.1|refseq:XP_017450559.1|refseq:XP_017450560.1|interpro:IPR015898(G-protein, gamma-like subunit)|interpro:IPR036284|interpro:IPR001770(G-protein, gamma subunit)|rgd:61860	-	-	-	figure legend:st1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10116(rat-brain-cortex)|taxid:10116(Rattus norvegicus brain cortex)	-	2020/10/30	2020/10/30	rogid:DtE+ZXAZKdCMvUW5K+jXQ5bH07M10116	rogid:emXrfwb8vVQD8eiFuTNcSGO/ba410116	rigid:3wclwrjZRvafcOruQOYnegkn54c	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q5XIE8	uniprotkb:Q9WTT6	intact:EBI-15348306|ensembl:ENSRNOP00000023037	intact:EBI-26438629	psi-mi:itm2b_rat(display_long)|uniprotkb:Itm2b(gene name)|psi-mi:Itm2b(display_short)|uniprotkb:Immature BRI2(gene name synonym)|uniprotkb:Transmembrane protein BRI(gene name synonym)	psi-mi:guad_rat(display_long)|uniprotkb:Gda(gene name)|psi-mi:Gda(display_short)|uniprotkb:Guanine aminohydrolase(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Martins et al. (2018)	imex:IM-28469|pubmed:29476059	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26439741|imex:IM-28469-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSRNOG00000016271(gene)|ensembl:ENSRNOT00000023037(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001540"(amyloid-beta binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0010008"(endosome membrane)|go:"GO:0030660"(Golgi-associated vesicle membrane)|go:"GO:0031301"(integral component of organelle membrane)|go:"GO:0042985"(negative regulation of amyloid precursor protein biosynthetic process)|interpro:IPR007084(BRICHOS)|interpro:IPR040145|mint:Q5XIE8|refseq:NP_001006964.1|rgd:620727	go:"GO:0005829"(cytosol)|go:"GO:0006147"(guanine catabolic process)|go:"GO:0006161"(deoxyguanosine catabolic process)|go:"GO:0008270"(zinc ion binding)|go:"GO:0008892"(guanine deaminase activity)|go:"GO:0019239"(deaminase activity)|go:"GO:0019428"(allantoin biosynthetic process)|go:"GO:0031116"(positive regulation of microtubule polymerization)|go:"GO:0046038"(GMP catabolic process)|go:"GO:0046055"(dGMP catabolic process)|go:"GO:0046098"(guanine metabolic process)|reactome:R-RNO-74259|mint:Q9WTT6|interpro:IPR006680(Amidohydrolase 1)|interpro:IPR014311(Guanine deaminase)|interpro:IPR011059(Metal-dependent hydrolase, composite)|interpro:IPR032466|rgd:621617	-	-	-	figure legend:st1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10116(rat-brain-cortex)|taxid:10116(Rattus norvegicus brain cortex)	-	2020/10/30	2020/10/30	rogid:DtE+ZXAZKdCMvUW5K+jXQ5bH07M10116	rogid:zR0aVjiumAbXWK0m7BKpRP2omzM10116	rigid:3wclwrjZRvafcOruQOYnegkn54c	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q5XIE8	uniprotkb:P08644	intact:EBI-15348306|ensembl:ENSRNOP00000023037	intact:EBI-26438533|ensembl:ENSRNOP00000012588|uniprotkb:P46203|uniprotkb:P97914	psi-mi:itm2b_rat(display_long)|uniprotkb:Itm2b(gene name)|psi-mi:Itm2b(display_short)|uniprotkb:Immature BRI2(gene name synonym)|uniprotkb:Transmembrane protein BRI(gene name synonym)	psi-mi:rask_rat(display_long)|uniprotkb:Kras(gene name)|psi-mi:Kras(display_short)|uniprotkb:Kras2(gene name synonym)|uniprotkb:K-Ras 2(gene name synonym)|uniprotkb:Ki-Ras(gene name synonym)|uniprotkb:c-K-ras(gene name synonym)|uniprotkb:c-Ki-ras(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Martins et al. (2018)	imex:IM-28469|pubmed:29476059	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26439741|imex:IM-28469-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSRNOG00000016271(gene)|ensembl:ENSRNOT00000023037(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001540"(amyloid-beta binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0010008"(endosome membrane)|go:"GO:0030660"(Golgi-associated vesicle membrane)|go:"GO:0031301"(integral component of organelle membrane)|go:"GO:0042985"(negative regulation of amyloid precursor protein biosynthetic process)|interpro:IPR007084(BRICHOS)|interpro:IPR040145|mint:Q5XIE8|refseq:NP_001006964.1|rgd:620727	reactome:R-RNO-5658442|reactome:R-RNO-5673000|reactome:R-RNO-5673001|reactome:R-RNO-5674135|reactome:R-RNO-5675221|reactome:R-RNO-8849471|reactome:R-RNO-8851805|reactome:R-RNO-9607240|reactome:R-RNO-9634635|reactome:R-RNO-9648002|reactome:R-RNO-9674555|ensembl:ENSRNOG00000009338(gene)|go:"GO:0005525"(GTP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0007265"(Ras protein signal transduction)|go:"GO:0007565"(female pregnancy)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0008542"(visual learning)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0016020"(membrane)|go:"GO:0019002"(GMP binding)|go:"GO:0019003"(GDP binding)|go:"GO:0019221"(cytokine-mediated signaling pathway)|go:"GO:0021897"(forebrain astrocyte development)|go:"GO:0030036"(actin cytoskeleton organization)|go:"GO:0030275"(LRR domain binding)|go:"GO:0031234"(extrinsic component of cytoplasmic side of plasma membrane)|go:"GO:0031647"(regulation of protein stability)|go:"GO:0032228"(regulation of synaptic transmission, GABAergic)|go:"GO:0035022"(positive regulation of Rac protein signal transduction)|go:"GO:0035900"(response to isolation stress)|ensembl:ENSRNOT00000012588(transcript)|go:"GO:0001889"(liver development)|go:"GO:0001934"(positive regulation of protein phosphorylation)|go:"GO:0003924"(GTPase activity)|go:"GO:0003925"(G protein activity)|go:"GO:0043406"(positive regulation of MAP kinase activity)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045121"(membrane raft)|go:"GO:0045596"(negative regulation of cell differentiation)|go:"GO:0048169"(regulation of long-term neuronal synaptic plasticity)|go:"GO:0048873"(homeostasis of number of cells within a tissue)|go:"GO:0051000"(positive regulation of nitric-oxide synthase activity)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|go:"GO:0051146"(striated muscle cell differentiation)|go:"GO:0051384"(response to glucocorticoid)|go:"GO:0051385"(response to mineralocorticoid)|go:"GO:0060441"(epithelial tube branching involved in lung morphogenesis)|go:"GO:2000774"(positive regulation of cellular senescence)|interpro:IPR001806(Ras GTPase)|interpro:IPR005225(Small GTP-binding protein)|go:"GO:0038002"(endocrine signaling)|interpro:IPR027417|mint:P08644|rcsb pdb:1N4S|reactome:R-RNO-1169092|reactome:R-RNO-1250347|reactome:R-RNO-1433557|reactome:R-RNO-171007|reactome:R-RNO-179812|reactome:R-RNO-180336|reactome:R-RNO-186763|reactome:R-RNO-1963640|reactome:R-RNO-210993|reactome:R-RNO-2179392|reactome:R-RNO-2424491|reactome:R-RNO-2871796|reactome:R-RNO-375165|reactome:R-RNO-4086398|reactome:R-RNO-5218921|reactome:R-RNO-5621575|reactome:R-RNO-5654688|reactome:R-RNO-5654693|reactome:R-RNO-5654699|reactome:R-RNO-5654700|reactome:R-RNO-5654704|reactome:R-RNO-5654706|reactome:R-RNO-5654712|interpro:IPR020849|reactome:R-RNO-5654719|refseq:NP_113703.1|refseq:XP_008761576.1|refseq:XP_017447931.1|refseq:XP_017447932.1|rgd:2981	-	-	-	figure legend:st1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10116(rat-brain-cortex)|taxid:10116(Rattus norvegicus brain cortex)	-	2020/10/30	2020/10/30	rogid:DtE+ZXAZKdCMvUW5K+jXQ5bH07M10116	rogid:wRpf3zq2kO/Q0QbC/wp+rJNrBlQ10116	rigid:3wclwrjZRvafcOruQOYnegkn54c	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q5XIE8	uniprotkb:P04797	intact:EBI-15348306|ensembl:ENSRNOP00000023037	intact:EBI-349219|uniprotkb:P09328|ensembl:ENSRNOP00000040878|uniprotkb:Q5M916|uniprotkb:Q9QWU4|intact:EBI-6096024	psi-mi:itm2b_rat(display_long)|uniprotkb:Itm2b(gene name)|psi-mi:Itm2b(display_short)|uniprotkb:Immature BRI2(gene name synonym)|uniprotkb:Transmembrane protein BRI(gene name synonym)	psi-mi:g3p_rat(display_long)|uniprotkb:Gapdh(gene name)|psi-mi:Gapdh(display_short)|uniprotkb:38 kDa BFA-dependent ADP-ribosylation substrate(gene name synonym)|uniprotkb:BARS-38(gene name synonym)|uniprotkb:Gapd(gene name synonym)|uniprotkb:Peptidyl-cysteine S-nitrosylase GAPDH(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Martins et al. (2018)	imex:IM-28469|pubmed:29476059	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26439741|imex:IM-28469-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSRNOG00000016271(gene)|ensembl:ENSRNOT00000023037(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001540"(amyloid-beta binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0010008"(endosome membrane)|go:"GO:0030660"(Golgi-associated vesicle membrane)|go:"GO:0031301"(integral component of organelle membrane)|go:"GO:0042985"(negative regulation of amyloid precursor protein biosynthetic process)|interpro:IPR007084(BRICHOS)|interpro:IPR040145|mint:Q5XIE8|refseq:NP_001006964.1|rgd:620727	rgd:2661|refseq:NP_058704.1|ensembl:ENSRNOG00000018630(gene)|ensembl:ENSRNOT00000050443(transcript)|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0001819"(positive regulation of cytokine production)|go:"GO:0004365"("glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity")|interpro:IPR020831|interpro:IPR036291|mint:P04797|reactome:R-RNO-70171|reactome:R-RNO-70263|go:"GO:0005737"(cytoplasm)|go:"GO:0005811"(lipid droplet)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005975"(carbohydrate metabolic process)|go:"GO:0006094"(gluconeogenesis)|go:"GO:0006096"(glycolytic process)|go:"GO:0006915"(apoptotic process)|go:"GO:0007565"(female pregnancy)|go:"GO:0008017"(microtubule binding)|go:"GO:0010951"(negative regulation of endopeptidase activity)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0017148"(negative regulation of translation)|go:"GO:0019828"(aspartic-type endopeptidase inhibitor activity)|go:"GO:0019899"(enzyme binding)|go:"GO:0019933"(cAMP-mediated signaling)|go:"GO:0031640"(killing of cells of another organism)|go:"GO:0005634"(nucleus)|go:"GO:0032481"(positive regulation of type I interferon production)|go:"GO:0050821"(protein stabilization)|go:"GO:0050832"(defense response to fungus)|go:"GO:0051287"(NAD binding)|go:"GO:0035605"(peptidyl-cysteine S-nitrosylase activity)|go:"GO:0051402"(neuron apoptotic process)|go:"GO:0051873"(killing by host of symbiont cells)|go:"GO:0035606"(peptidyl-cysteine S-trans-nitrosylation)|go:"GO:0060359"(response to ammonium ion)|go:"GO:0061844"(antimicrobial humoral immune response mediated by antimicrobial peptide)|go:"GO:0042802"(identical protein binding)|go:"GO:0071346"(cellular response to interferon-gamma)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0097452"(GAIT complex)|go:"GO:0097718"(disordered domain specific binding)|go:"GO:0050661"(NADP binding)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099092"(postsynaptic density, intracellular component)|go:"GO:1905460"(negative regulation of vascular associated smooth muscle cell apoptotic process)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR006424(Glyceraldehyde-3-phosphate dehydrogenase, type I)|interpro:IPR020828|interpro:IPR020829|interpro:IPR020830|refseq:XP_017447924.1|refseq:XP_017458425.1	-	-	-	figure legend:st1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10116(rat-brain-cortex)|taxid:10116(Rattus norvegicus brain cortex)	-	2020/10/30	2020/10/30	rogid:DtE+ZXAZKdCMvUW5K+jXQ5bH07M10116	rogid:4TDODEC0WVLzUSY2w1fVSmP9C5010116	rigid:3wclwrjZRvafcOruQOYnegkn54c	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q5XIE8	uniprotkb:Q00960	intact:EBI-15348306|ensembl:ENSRNOP00000023037	intact:EBI-396905|uniprotkb:Q62684	psi-mi:itm2b_rat(display_long)|uniprotkb:Itm2b(gene name)|psi-mi:Itm2b(display_short)|uniprotkb:Immature BRI2(gene name synonym)|uniprotkb:Transmembrane protein BRI(gene name synonym)	psi-mi:nmde2_rat(display_long)|uniprotkb:Grin2b(gene name)|psi-mi:Grin2b(display_short)|uniprotkb:Glutamate [NMDA] receptor subunit epsilon-2(gene name synonym)|uniprotkb:N-methyl D-aspartate receptor subtype 2B(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Martins et al. (2018)	imex:IM-28469|pubmed:29476059	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26439741|imex:IM-28469-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSRNOG00000016271(gene)|ensembl:ENSRNOT00000023037(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001540"(amyloid-beta binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0010008"(endosome membrane)|go:"GO:0030660"(Golgi-associated vesicle membrane)|go:"GO:0031301"(integral component of organelle membrane)|go:"GO:0042985"(negative regulation of amyloid precursor protein biosynthetic process)|interpro:IPR007084(BRICHOS)|interpro:IPR040145|mint:Q5XIE8|refseq:NP_001006964.1|rgd:620727	rgd:2738|refseq:NP_036706.1|go:"GO:0001508"(action potential)|go:"GO:0001662"(behavioral fear response)|go:"GO:0036094"(small molecule binding)|go:"GO:0038023"(signaling receptor activity)|go:"GO:0042165"(neurotransmitter binding)|go:"GO:0042220"(response to cocaine)|go:"GO:0042596"(fear response)|go:"GO:0042734"(presynaptic membrane)|go:"GO:0043005"(neuron projection)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043083"(synaptic cleft)|go:"GO:0043113"(receptor clustering)|go:"GO:0043195"(terminal bouton)|go:"GO:0043197"(dendritic spine)|go:"GO:0043408"(regulation of MAPK cascade)|go:"GO:0044307"(dendritic branch)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045202"(synapse)|go:"GO:0045211"(postsynaptic membrane)|go:"GO:0045471"(response to ethanol)|go:"GO:0046960"(sensitization)|go:"GO:0048167"(regulation of synaptic plasticity)|go:"GO:0048169"(regulation of long-term neuronal synaptic plasticity)|go:"GO:0048266"(behavioral response to pain)|go:"GO:0048511"(rhythmic process)|go:"GO:0050806"(positive regulation of synaptic transmission)|go:"GO:0050839"(cell adhesion molecule binding)|go:"GO:0050966"(detection of mechanical stimulus involved in sensory perception of pain)|go:"GO:0051290"(protein heterotetramerization)|go:"GO:0051592"(response to calcium ion)|go:"GO:0051597"(response to methylmercury)|go:"GO:0051602"(response to electrical stimulus)|go:"GO:0051707"(response to other organism)|go:"GO:0060078"(regulation of postsynaptic membrane potential)|go:"GO:0060079"(excitatory postsynaptic potential)|go:"GO:0060291"(long-term synaptic potentiation)|go:"GO:0060416"(response to growth hormone)|go:"GO:0060992"(response to fungicide)|go:"GO:0071230"(cellular response to amino acid stimulus)|go:"GO:0071287"(cellular response to manganese ion)|go:"GO:0071359"(cellular response to dsRNA)|go:"GO:0071363"(cellular response to growth factor stimulus)|go:"GO:0071386"(cellular response to corticosterone stimulus)|go:"GO:0071396"(cellular response to lipid)|go:"GO:0071407"(cellular response to organic cyclic compound)|go:"GO:0097060"(synaptic membrane)|go:"GO:0097110"(scaffold protein binding)|go:"GO:0097440"(apical dendrite)|go:"GO:0097553"(calcium ion transmembrane import into cytosol)|go:"GO:0098686"(hippocampal mossy fiber to CA3 synapse)|go:"GO:0098688"(parallel fiber to Purkinje cell synapse)|go:"GO:0098794"(postsynapse)|go:"GO:0098839"(postsynaptic density membrane)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0098989"(NMDA selective glutamate receptor signaling pathway)|go:"GO:0099056"(integral component of presynaptic membrane)|go:"GO:0099061"(integral component of postsynaptic density membrane)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006812"(cation transport)|go:"GO:0006816"(calcium ion transport)|go:"GO:0007268"(chemical synaptic transmission)|go:"GO:0007423"(sensory organ development)|go:"GO:0007611"(learning or memory)|go:"GO:0007612"(learning)|go:"GO:0007613"(memory)|go:"GO:0007616"(long-term memory)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0008270"(zinc ion binding)|go:"GO:0008306"(associative learning)|go:"GO:0009612"(response to mechanical stimulus)|go:"GO:0009636"(response to toxic substance)|go:"GO:0009743"(response to carbohydrate)|go:"GO:0009986"(cell surface)|go:"GO:0010042"(response to manganese ion)|go:"GO:0010243"(response to organonitrogen compound)|go:"GO:0010350"(cellular response to magnesium starvation)|go:"GO:0010738"(regulation of protein kinase A signaling)|go:"GO:0010942"(positive regulation of cell death)|go:"GO:0014049"(positive regulation of glutamate secretion)|go:"GO:0014069"(postsynaptic density)|go:"GO:0014070"(response to organic cyclic compound)|go:"GO:0014075"(response to amine)|go:"GO:0015276"(ligand-gated ion channel activity)|go:"GO:0016020"(membrane)|go:"GO:0016594"(glycine binding)|go:"GO:0016595"(glutamate binding)|go:"GO:0017146"(NMDA selective glutamate receptor complex)|go:"GO:0021766"(hippocampus development)|go:"GO:0021987"(cerebral cortex development)|go:"GO:0022849"(glutamate-gated calcium ion channel activity)|go:"GO:0030018"(Z disc)|go:"GO:0031749"(D2 dopamine receptor binding)|go:"GO:0005856"(cytoskeleton)|go:"GO:0032026"(response to magnesium ion)|go:"GO:0033555"(multicellular organismal response to stress)|go:"GO:0034097"(response to cytokine)|go:"GO:0035235"(ionotropic glutamate receptor signaling pathway)|go:"GO:0035255"(ionotropic glutamate receptor binding)|go:"GO:0099583"(neurotransmitter receptor activity involved in regulation of postsynaptic cytosolic calcium ion concentration)|go:"GO:0099566"(regulation of postsynaptic cytosolic calcium ion concentration)|go:"GO:1901216"(positive regulation of neuron death)|go:"GO:1902951"(negative regulation of dendritic spine maintenance)|go:"GO:1904315"(transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential)|go:"GO:1904322"(cellular response to forskolin)|go:"GO:1904644"(cellular response to curcumin)|go:"GO:2001056"(positive regulation of cysteine-type endopeptidase activity)|interpro:IPR001320(Ionotropic glutamate receptor)|interpro:IPR001508(NMDA receptor)|interpro:IPR001828(Extracellular ligand-binding receptor)|interpro:IPR018884|interpro:IPR019594|interpro:IPR028082|rcsb pdb:3JPW|rcsb pdb:3JPY|rcsb pdb:3QEL|rcsb pdb:3QEM|rcsb pdb:4PE5|rcsb pdb:5B3J|rcsb pdb:5FXG|rcsb pdb:5FXH|rcsb pdb:5FXI|rcsb pdb:5FXJ|rcsb pdb:5FXK|rcsb pdb:5TPZ|rcsb pdb:6CNA|rcsb pdb:6E7R|rcsb pdb:6E7S|rcsb pdb:6E7T|rcsb pdb:6E7U|rcsb pdb:6E7V|rcsb pdb:6E7W|rcsb pdb:6E7X|rcsb pdb:6WHR|rcsb pdb:6WHS|rcsb pdb:6WHT|rcsb pdb:6WHU|rcsb pdb:6WHV|rcsb pdb:6WHW|rcsb pdb:6WHX|rcsb pdb:6WHY|rcsb pdb:6WI0|rcsb pdb:6WI1|reactome:R-RNO-3928662|reactome:R-RNO-438066|reactome:R-RNO-5673001|reactome:R-RNO-8849932|reactome:R-RNO-9609736|go:"GO:0001666"(response to hypoxia)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0001964"(startle response)|go:"GO:0001967"(suckling behavior)|go:"GO:0001975"(response to amphetamine)|go:"GO:0004970"(ionotropic glutamate receptor activity)|go:"GO:0004972"(NMDA glutamate receptor activity)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005149"(interleukin-1 receptor binding)|go:"GO:0005234"(extracellularly glutamate-gated ion channel activity)|go:"GO:0005261"(cation channel activity)|go:"GO:0005262"(calcium channel activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005764"(lysosome)|go:"GO:0005770"(late endosome)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0099529"(neurotransmitter receptor activity involved in regulation of postsynaptic membrane potential)|mint:Q00960|dip:DIP-33702N	-	-	-	figure legend:st1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10116(rat-brain-cortex)|taxid:10116(Rattus norvegicus brain cortex)	-	2020/10/30	2020/10/30	rogid:DtE+ZXAZKdCMvUW5K+jXQ5bH07M10116	rogid:dbOLObdhW/ts7GuZ0k8UIII99m010116	rigid:3wclwrjZRvafcOruQOYnegkn54c	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q5XIE8	uniprotkb:P35439	intact:EBI-15348306|ensembl:ENSRNOP00000023037	intact:EBI-877897|ensembl:ENSRNOP00000049198|uniprotkb:Q62646	psi-mi:itm2b_rat(display_long)|uniprotkb:Itm2b(gene name)|psi-mi:Itm2b(display_short)|uniprotkb:Immature BRI2(gene name synonym)|uniprotkb:Transmembrane protein BRI(gene name synonym)	psi-mi:nmdz1_rat(display_long)|uniprotkb:N-methyl-D-aspartate receptor subunit NR1(gene name synonym)|uniprotkb:Grin1(gene name)|psi-mi:Grin1(display_short)|uniprotkb:Nmdar1(gene name synonym)|uniprotkb:Glutamate [NMDA] receptor subunit zeta-1(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Martins et al. (2018)	imex:IM-28469|pubmed:29476059	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26439741|imex:IM-28469-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSRNOG00000016271(gene)|ensembl:ENSRNOT00000023037(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001540"(amyloid-beta binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0010008"(endosome membrane)|go:"GO:0030660"(Golgi-associated vesicle membrane)|go:"GO:0031301"(integral component of organelle membrane)|go:"GO:0042985"(negative regulation of amyloid precursor protein biosynthetic process)|interpro:IPR007084(BRICHOS)|interpro:IPR040145|mint:Q5XIE8|refseq:NP_001006964.1|rgd:620727	go:"GO:0007612"(learning)|go:"GO:0007613"(memory)|go:"GO:0007616"(long-term memory)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0008306"(associative learning)|go:"GO:0008344"(adult locomotory behavior)|go:"GO:0008355"(olfactory learning)|go:"GO:0008542"(visual learning)|go:"GO:0009986"(cell surface)|go:"GO:0010524"(positive regulation of calcium ion transport into cytosol)|go:"GO:0010646"(regulation of cell communication)|go:"GO:0010942"(positive regulation of cell death)|go:"GO:0014069"(postsynaptic density)|go:"GO:0014070"(response to organic cyclic compound)|go:"GO:0014075"(response to amine)|go:"GO:0015276"(ligand-gated ion channel activity)|go:"GO:0016020"(membrane)|go:"GO:0016594"(glycine binding)|go:"GO:0016595"(glutamate binding)|go:"GO:0017146"(NMDA selective glutamate receptor complex)|go:"GO:0018964"(propylene metabolic process)|go:"GO:0019233"(sensory perception of pain)|go:"GO:0019899"(enzyme binding)|go:"GO:0019902"(phosphatase binding)|go:"GO:0021586"(pons maturation)|go:"GO:0021987"(cerebral cortex development)|go:"GO:0022843"(voltage-gated cation channel activity)|go:"GO:0022849"(glutamate-gated calcium ion channel activity)|go:"GO:0030425"(dendrite)|go:"GO:0030672"(synaptic vesicle membrane)|go:"GO:0032590"(dendrite membrane)|go:"GO:0035176"(social behavior)|go:"GO:0035235"(ionotropic glutamate receptor signaling pathway)|go:"GO:0035249"(synaptic transmission, glutamatergic)|go:"GO:0035254"(glutamate receptor binding)|go:"GO:0038023"(signaling receptor activity)|go:"GO:0042165"(neurotransmitter binding)|go:"GO:0042391"(regulation of membrane potential)|go:"GO:0043005"(neuron projection)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043083"(synaptic cleft)|go:"GO:0043195"(terminal bouton)|go:"GO:0043197"(dendritic spine)|go:"GO:0043278"(response to morphine)|go:"GO:0043523"(regulation of neuron apoptotic process)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0043576"(regulation of respiratory gaseous exchange)|go:"GO:0044307"(dendritic branch)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045202"(synapse)|go:"GO:0045211"(postsynaptic membrane)|ensembl:ENSRNOG00000011726(gene)|ensembl:ENSRNOT00000049297(transcript)|go:"GO:0001540"(amyloid-beta binding)|go:"GO:0001661"(conditioned taste aversion)|go:"GO:0001964"(startle response)|go:"GO:0001967"(suckling behavior)|go:"GO:0001975"(response to amphetamine)|go:"GO:0004970"(ionotropic glutamate receptor activity)|go:"GO:0004972"(NMDA glutamate receptor activity)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005261"(cation channel activity)|go:"GO:0005262"(calcium channel activity)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006812"(cation transport)|go:"GO:0006816"(calcium ion transport)|go:"GO:0006874"(cellular calcium ion homeostasis)|go:"GO:0007268"(chemical synaptic transmission)|go:"GO:0007611"(learning or memory)|rgd:2736|refseq:NP_058706.1|refseq:NP_001274352.1|refseq:NP_001257531.1|refseq:NP_001257532.1|refseq:NP_001257534.1|refseq:NP_001257537.1|refseq:NP_001257539.1|dip:DIP-674N|go:"GO:0045471"(response to ethanol)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048167"(regulation of synaptic plasticity)|go:"GO:0048168"(regulation of neuronal synaptic plasticity)|go:"GO:0048169"(regulation of long-term neuronal synaptic plasticity)|go:"GO:0048511"(rhythmic process)|go:"GO:0048814"(regulation of dendrite morphogenesis)|go:"GO:0050770"(regulation of axonogenesis)|go:"GO:0050905"(neuromuscular process)|go:"GO:0051290"(protein heterotetramerization)|go:"GO:0051592"(response to calcium ion)|go:"GO:0051963"(regulation of synapse assembly)|go:"GO:0055074"(calcium ion homeostasis)|go:"GO:0060076"(excitatory synapse)|go:"GO:0060079"(excitatory postsynaptic potential)|go:"GO:0060134"(prepulse inhibition)|go:"GO:0060179"(male mating behavior)|go:"GO:0060992"(response to fungicide)|go:"GO:0065003"(protein-containing complex assembly)|go:"GO:0071287"(cellular response to manganese ion)|go:"GO:0097060"(synaptic membrane)|go:"GO:0097553"(calcium ion transmembrane import into cytosol)|go:"GO:0098686"(hippocampal mossy fiber to CA3 synapse)|go:"GO:0098688"(parallel fiber to Purkinje cell synapse)|go:"GO:0098839"(postsynaptic density membrane)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099056"(integral component of presynaptic membrane)|go:"GO:0099061"(integral component of postsynaptic density membrane)|go:"GO:0099507"(ligand-gated ion channel activity involved in regulation of presynaptic membrane potential)|go:"GO:1900149"(positive regulation of Schwann cell migration)|go:"GO:1902952"(positive regulation of dendritic spine maintenance)|go:"GO:1903428"(positive regulation of reactive oxygen species biosynthetic process)|go:"GO:1903539"(protein localization to postsynaptic membrane)|go:"GO:1904315"(transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential)|go:"GO:1905429"(response to glycine)|go:"GO:2000463"(positive regulation of excitatory postsynaptic potential)|go:"GO:2001056"(positive regulation of cysteine-type endopeptidase activity)|interpro:IPR001320(Ionotropic glutamate receptor)|interpro:IPR001508(NMDA receptor)|interpro:IPR001828(Extracellular ligand-binding receptor)|interpro:IPR018882|interpro:IPR019594|interpro:IPR028082|mint:P35439|rcsb pdb:1PB7|rcsb pdb:1PB8|rcsb pdb:1PB9|rcsb pdb:1PBQ|rcsb pdb:1Y1M|rcsb pdb:1Y1Z|rcsb pdb:1Y20|rcsb pdb:2A5T|rcsb pdb:3Q41|rcsb pdb:4KCC|rcsb pdb:4KFQ|rcsb pdb:4NF4|rcsb pdb:4NF5|rcsb pdb:4NF6|rcsb pdb:4NF8|rcsb pdb:4PE5|rcsb pdb:5DEX|rcsb pdb:5FXG|rcsb pdb:5FXH|rcsb pdb:5FXI|rcsb pdb:5FXJ|rcsb pdb:5FXK|rcsb pdb:5I56|rcsb pdb:5I57|rcsb pdb:5I58|rcsb pdb:5I59|rcsb pdb:5JTY|rcsb pdb:5U8C|rcsb pdb:5VIH|rcsb pdb:5VII|rcsb pdb:5VIJ|rcsb pdb:6CNA|rcsb pdb:6MM9|rcsb pdb:6MMA|rcsb pdb:6MMB|rcsb pdb:6MMG|rcsb pdb:6MMH|rcsb pdb:6MMI|rcsb pdb:6MMJ|rcsb pdb:6MMK|rcsb pdb:6MML|rcsb pdb:6MMM|rcsb pdb:6MMN|rcsb pdb:6MMP|rcsb pdb:6MMR|rcsb pdb:6MMS|rcsb pdb:6MMT|rcsb pdb:6MMU|rcsb pdb:6MMV|rcsb pdb:6MMW|rcsb pdb:6MMX|rcsb pdb:6OVD|rcsb pdb:6OVE|rcsb pdb:6USU|rcsb pdb:6USV|rcsb pdb:6UZ6|rcsb pdb:6UZG|rcsb pdb:6UZR|rcsb pdb:6UZW|rcsb pdb:6UZX|rcsb pdb:6WHR|rcsb pdb:6WHS|rcsb pdb:6WHT|rcsb pdb:6WHU|rcsb pdb:6WHV|rcsb pdb:6WHW|rcsb pdb:6WHX|rcsb pdb:6WHY|rcsb pdb:6WI0|rcsb pdb:6WI1|reactome:R-RNO-3928662|reactome:R-RNO-438066|reactome:R-RNO-5673001|reactome:R-RNO-8849932|reactome:R-RNO-9609736	-	-	-	figure legend:st1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10116(rat-brain-cortex)|taxid:10116(Rattus norvegicus brain cortex)	-	2020/10/30	2020/10/30	rogid:DtE+ZXAZKdCMvUW5K+jXQ5bH07M10116	rogid:zp3bKY55ROKfZfbAfhNN53skUYY10116	rigid:3wclwrjZRvafcOruQOYnegkn54c	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q5XIE8	uniprotkb:P19490	intact:EBI-15348306|ensembl:ENSRNOP00000023037	intact:EBI-371642	psi-mi:itm2b_rat(display_long)|uniprotkb:Itm2b(gene name)|psi-mi:Itm2b(display_short)|uniprotkb:Immature BRI2(gene name synonym)|uniprotkb:Transmembrane protein BRI(gene name synonym)	psi-mi:gria1_rat(display_long)|uniprotkb:Gria1(gene name)|psi-mi:Gria1(display_short)|uniprotkb:GluR-A(gene name synonym)|uniprotkb:GluR-K1(gene name synonym)|uniprotkb:Glutamate receptor ionotropic, AMPA 1(gene name synonym)|uniprotkb:AMPA-selective glutamate receptor 1(gene name synonym)|uniprotkb:Glur1(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Martins et al. (2018)	imex:IM-28469|pubmed:29476059	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26439741|imex:IM-28469-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSRNOG00000016271(gene)|ensembl:ENSRNOT00000023037(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001540"(amyloid-beta binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0010008"(endosome membrane)|go:"GO:0030660"(Golgi-associated vesicle membrane)|go:"GO:0031301"(integral component of organelle membrane)|go:"GO:0042985"(negative regulation of amyloid precursor protein biosynthetic process)|interpro:IPR007084(BRICHOS)|interpro:IPR040145|mint:Q5XIE8|refseq:NP_001006964.1|rgd:620727	rgd:621531|refseq:NP_113796.1|go:"GO:0014069"(postsynaptic density)|go:"GO:0014070"(response to organic cyclic compound)|go:"GO:0015276"(ligand-gated ion channel activity)|go:"GO:0016020"(membrane)|go:"GO:0019228"(neuronal action potential)|go:"GO:0019865"(immunoglobulin binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0021510"(spinal cord development)|go:"GO:0030165"(PDZ domain binding)|go:"GO:0030425"(dendrite)|go:"GO:0030672"(synaptic vesicle membrane)|go:"GO:0031267"(small GTPase binding)|go:"GO:0031489"(myosin V binding)|go:"GO:0031594"(neuromuscular junction)|go:"GO:0031623"(receptor internalization)|go:"GO:0031681"(G-protein beta-subunit binding)|go:"GO:0031698"(beta-2 adrenergic receptor binding)|go:"GO:0031901"(early endosome membrane)|go:"GO:0032279"(asymmetric synapse)|go:"GO:0032281"(AMPA glutamate receptor complex)|go:"GO:0032355"(response to estradiol)|go:"GO:0032590"(dendrite membrane)|go:"GO:0032591"(dendritic spine membrane)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035249"(synaptic transmission, glutamatergic)|go:"GO:0035254"(glutamate receptor binding)|go:"GO:0036477"(somatodendritic compartment)|go:"GO:0038023"(signaling receptor activity)|go:"GO:0042220"(response to cocaine)|go:"GO:0042493"|go:"GO:0042802"(identical protein binding)|go:"GO:0043005"(neuron projection)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043197"(dendritic spine)|go:"GO:0043198"(dendritic shaft)|go:"GO:0043434"(response to peptide hormone)|go:"GO:0044297"(cell body)|go:"GO:0044308"(axonal spine)|go:"GO:0044309"(neuron spine)|go:"GO:0045202"(synapse)|go:"GO:0045211"(postsynaptic membrane)|go:"GO:0045838"(positive regulation of membrane potential)|go:"GO:0046685"(response to arsenic-containing substance)|go:"GO:0048167"(regulation of synaptic plasticity)|go:"GO:0050804"(modulation of chemical synaptic transmission)|go:"GO:0050806"(positive regulation of synaptic transmission)|go:"GO:0051018"(protein kinase A binding)|go:"GO:0051602"(response to electrical stimulus)|go:"GO:0055037"(recycling endosome)|go:"GO:0055038"(recycling endosome membrane)|go:"GO:0060076"(excitatory synapse)|go:"GO:0060078"(regulation of postsynaptic membrane potential)|go:"GO:0060292"(long-term synaptic depression)|go:"GO:0060992"(response to fungicide)|go:"GO:0071230"(cellular response to amino acid stimulus)|go:"GO:0071242"(cellular response to ammonium ion)|go:"GO:0071359"(cellular response to dsRNA)|go:"GO:0071363"(cellular response to growth factor stimulus)|go:"GO:0071375"(cellular response to peptide hormone stimulus)|go:"GO:0071407"(cellular response to organic cyclic compound)|go:"GO:0071418"(cellular response to amine stimulus)|go:"GO:0009636"(response to toxic substance)|go:"GO:0009986"(cell surface)|go:"GO:0010226"(response to lithium ion)|go:"GO:0097110"(scaffold protein binding)|go:"GO:0098794"(postsynapse)|go:"GO:0098839"(postsynaptic density membrane)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099055"(integral component of postsynaptic membrane)|go:"GO:0099056"(integral component of presynaptic membrane)|go:"GO:0099061"(integral component of postsynaptic density membrane)|go:"GO:0099544"(perisynaptic space)|go:"GO:0099583"(neurotransmitter receptor activity involved in regulation of postsynaptic cytosolic calcium ion concentration)|go:"GO:1904315"(transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential)|interpro:IPR001320(Ionotropic glutamate receptor)|interpro:IPR001508(NMDA receptor)|interpro:IPR001828(Extracellular ligand-binding receptor)|interpro:IPR019594|interpro:IPR028082|rcsb pdb:2AWW|rcsb pdb:2G2L|rcsb pdb:3SAJ|go:"GO:0097060"(synaptic membrane)|rcsb pdb:6NJL|rcsb pdb:6NJN|rcsb pdb:6QKC|rcsb pdb:6QKZ|rcsb pdb:7OCA|rcsb pdb:7OCC|rcsb pdb:7OCD|rcsb pdb:7OCE|rcsb pdb:7OCF|reactome:R-RNO-204005|reactome:R-RNO-399710|reactome:R-RNO-399719|go:"GO:0001540"(amyloid-beta binding)|go:"GO:0001919"(regulation of receptor recycling)|go:"GO:0001965"(G-protein alpha-subunit binding)|go:"GO:0004970"(ionotropic glutamate receptor activity)|go:"GO:0004971"(AMPA glutamate receptor activity)|go:"GO:0005769"(early endosome)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0007268"(chemical synaptic transmission)|go:"GO:0007616"(long-term memory)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008179"(adenylate cyclase binding)|go:"GO:0008328"(ionotropic glutamate receptor complex)|reactome:R-RNO-438066|reactome:R-RNO-5694530|reactome:R-RNO-8849932|reactome:R-RNO-416993|mint:P19490|dip:DIP-30929N	-	-	-	figure legend:st1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10116(rat-brain-cortex)|taxid:10116(Rattus norvegicus brain cortex)	-	2020/10/30	2020/10/30	rogid:DtE+ZXAZKdCMvUW5K+jXQ5bH07M10116	rogid:Bdkl7msqLXWZxd8172jZFghg6BI10116	rigid:3wclwrjZRvafcOruQOYnegkn54c	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q5XIE8	uniprotkb:Q63228	intact:EBI-15348306|ensembl:ENSRNOP00000023037	intact:EBI-26438518	psi-mi:itm2b_rat(display_long)|uniprotkb:Itm2b(gene name)|psi-mi:Itm2b(display_short)|uniprotkb:Immature BRI2(gene name synonym)|uniprotkb:Transmembrane protein BRI(gene name synonym)	psi-mi:gmfb_rat(display_long)|uniprotkb:Gmfb(gene name)|psi-mi:Gmfb(display_short)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Martins et al. (2018)	imex:IM-28469|pubmed:29476059	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26439741|imex:IM-28469-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSRNOG00000016271(gene)|ensembl:ENSRNOT00000023037(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001540"(amyloid-beta binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0010008"(endosome membrane)|go:"GO:0030660"(Golgi-associated vesicle membrane)|go:"GO:0031301"(integral component of organelle membrane)|go:"GO:0042985"(negative regulation of amyloid precursor protein biosynthetic process)|interpro:IPR007084(BRICHOS)|interpro:IPR040145|mint:Q5XIE8|refseq:NP_001006964.1|rgd:620727	go:"GO:0003779"(actin binding)|go:"GO:0007612"(learning)|go:"GO:0007626"(locomotory behavior)|go:"GO:0008083"(growth factor activity)|go:"GO:0034316"(negative regulation of Arp2/3 complex-mediated actin nucleation)|go:"GO:0071846"(actin filament debranching)|go:"GO:0071933"(Arp2/3 complex binding)|mint:Q63228|refseq:NP_112294.1|interpro:IPR002108(Actin-binding, cofilin/tropomyosin type)|interpro:IPR029006|interpro:IPR011171(Glia maturation factor beta)|rgd:70910	-	-	-	figure legend:st1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10116(rat-brain-cortex)|taxid:10116(Rattus norvegicus brain cortex)	-	2020/10/30	2020/10/30	rogid:DtE+ZXAZKdCMvUW5K+jXQ5bH07M10116	rogid:8uuXr7GJkmPweXQ+i9yGVTsK2HU10116	rigid:3wclwrjZRvafcOruQOYnegkn54c	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q5XIE8	uniprotkb:Q3T1K5	intact:EBI-15348306|ensembl:ENSRNOP00000023037	intact:EBI-931686|ensembl:ENSRNOP00000072041	psi-mi:itm2b_rat(display_long)|uniprotkb:Itm2b(gene name)|psi-mi:Itm2b(display_short)|uniprotkb:Immature BRI2(gene name synonym)|uniprotkb:Transmembrane protein BRI(gene name synonym)	psi-mi:caza2_rat(display_long)|uniprotkb:Capza2(gene name)|psi-mi:Capza2(display_short)|uniprotkb:CapZ alpha-2(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Martins et al. (2018)	imex:IM-28469|pubmed:29476059	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26439741|imex:IM-28469-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSRNOG00000016271(gene)|ensembl:ENSRNOT00000023037(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001540"(amyloid-beta binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0010008"(endosome membrane)|go:"GO:0030660"(Golgi-associated vesicle membrane)|go:"GO:0031301"(integral component of organelle membrane)|go:"GO:0042985"(negative regulation of amyloid precursor protein biosynthetic process)|interpro:IPR007084(BRICHOS)|interpro:IPR040145|mint:Q5XIE8|refseq:NP_001006964.1|rgd:620727	rgd:1549770|refseq:NP_001009180.1|ensembl:ENSRNOG00000056207(gene)|ensembl:ENSRNOT00000090451(transcript)|go:"GO:0005903"(brush border)|go:"GO:0008290"(F-actin capping protein complex)|go:"GO:0016020"(membrane)|go:"GO:0030036"(actin cytoskeleton organization)|go:"GO:0030863"(cortical cytoskeleton)|go:"GO:0051015"(actin filament binding)|go:"GO:0051016"(barbed-end actin filament capping)|interpro:IPR002189(F-actin capping protein, alpha subunit)|interpro:IPR017865|interpro:IPR037282|interpro:IPR042276|interpro:IPR042489|mint:Q3T1K5|rcsb pdb:2KBM|reactome:R-RNO-2132295|reactome:R-RNO-3371497|reactome:R-RNO-6807878|reactome:R-RNO-6811436|reactome:R-RNO-879415|reactome:R-RNO-983231	-	-	-	figure legend:st1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10116(rat-brain-cortex)|taxid:10116(Rattus norvegicus brain cortex)	-	2020/10/30	2020/10/30	rogid:DtE+ZXAZKdCMvUW5K+jXQ5bH07M10116	rogid:9nxfEbrpHlDtTYwSvHAJvZLLweo10116	rigid:3wclwrjZRvafcOruQOYnegkn54c	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q5XIE8	uniprotkb:Q8CH84	intact:EBI-15348306|ensembl:ENSRNOP00000023037	intact:EBI-26438500	psi-mi:itm2b_rat(display_long)|uniprotkb:Itm2b(gene name)|psi-mi:Itm2b(display_short)|uniprotkb:Immature BRI2(gene name synonym)|uniprotkb:Transmembrane protein BRI(gene name synonym)	psi-mi:elav2_rat(display_long)|uniprotkb:Elavl2(gene name)|psi-mi:Elavl2(display_short)|uniprotkb:Hub(gene name synonym)|uniprotkb:Hu-antigen B(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Martins et al. (2018)	imex:IM-28469|pubmed:29476059	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26439741|imex:IM-28469-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSRNOG00000016271(gene)|ensembl:ENSRNOT00000023037(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001540"(amyloid-beta binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0010008"(endosome membrane)|go:"GO:0030660"(Golgi-associated vesicle membrane)|go:"GO:0031301"(integral component of organelle membrane)|go:"GO:0042985"(negative regulation of amyloid precursor protein biosynthetic process)|interpro:IPR007084(BRICHOS)|interpro:IPR040145|mint:Q5XIE8|refseq:NP_001006964.1|rgd:620727	go:"GO:0003723"(RNA binding)|go:"GO:0045202"(synapse)|go:"GO:1990830"(cellular response to leukemia inhibitory factor)|go:"GO:1990904"(ribonucleoprotein complex)|reactome:R-RNO-72163|mint:Q8CH84|interpro:IPR006548(Splicing factor ELAV/HuD)|interpro:IPR034775|interpro:IPR034999|interpro:IPR034914|interpro:IPR002343(Paraneoplastic encephalomyelitis antigen)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR035979|interpro:IPR000504(RNA recognition motif, RNP-1)|rgd:628611	-	-	-	figure legend:st1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10116(rat-brain-cortex)|taxid:10116(Rattus norvegicus brain cortex)	-	2020/10/30	2020/10/30	rogid:DtE+ZXAZKdCMvUW5K+jXQ5bH07M10116	rogid:9KuexJUg11SJJKKN0kZlVAyMkug10116	rigid:3wclwrjZRvafcOruQOYnegkn54c	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q5XIE8	uniprotkb:Q2TA68	intact:EBI-15348306|ensembl:ENSRNOP00000023037	intact:EBI-919238|uniprotkb:O08681|uniprotkb:Q5MPP1|uniprotkb:Q5MPP2|uniprotkb:Q5QJE9|uniprotkb:Q6B435|uniprotkb:Q6R611|ensembl:ENSRNOP00000002338|ensembl:ENSRNOP00000002343	psi-mi:itm2b_rat(display_long)|uniprotkb:Itm2b(gene name)|psi-mi:Itm2b(display_short)|uniprotkb:Immature BRI2(gene name synonym)|uniprotkb:Transmembrane protein BRI(gene name synonym)	psi-mi:opa1_rat(display_long)|uniprotkb:Opa1(gene name)|psi-mi:Opa1(display_short)|uniprotkb:Optic atrophy protein 1 homolog(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Martins et al. (2018)	imex:IM-28469|pubmed:29476059	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26439741|imex:IM-28469-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSRNOG00000016271(gene)|ensembl:ENSRNOT00000023037(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001540"(amyloid-beta binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0010008"(endosome membrane)|go:"GO:0030660"(Golgi-associated vesicle membrane)|go:"GO:0031301"(integral component of organelle membrane)|go:"GO:0042985"(negative regulation of amyloid precursor protein biosynthetic process)|interpro:IPR007084(BRICHOS)|interpro:IPR040145|mint:Q5XIE8|refseq:NP_001006964.1|rgd:620727	rgd:708423|refseq:NP_598269.3|refseq:XP_006248560.1|ensembl:ENSRNOG00000001717(gene)|ensembl:ENSRNOT00000002338(transcript)|ensembl:ENSRNOT00000002343(transcript)|go:"GO:0000002"(mitochondrial genome maintenance)|go:"GO:0000266"(mitochondrial fission)|go:"GO:0001843"(neural tube closure)|go:"GO:0003374"(dynamin family protein polymerization involved in mitochondrial fission)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005758"(mitochondrial intermembrane space)|go:"GO:0005829"(cytosol)|go:"GO:0006915"(apoptotic process)|go:"GO:0007005"(mitochondrion organization)|go:"GO:0007007"(inner mitochondrial membrane organization)|go:"GO:0007568"(aging)|go:"GO:0007601"(visual perception)|go:"GO:0008017"(microtubule binding)|go:"GO:0008053"(mitochondrial fusion)|go:"GO:0010636"(positive regulation of mitochondrial fusion)|go:"GO:0014042"(positive regulation of neuron maturation)|go:"GO:0014850"(response to muscle activity)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0019900"(kinase binding)|go:"GO:0030061"(mitochondrial crista)|go:"GO:0030425"(dendrite)|go:"GO:0031314"(extrinsic component of mitochondrial inner membrane)|go:"GO:0031667"(response to nutrient levels)|go:"GO:0031966"(mitochondrial membrane)|go:"GO:0036444"(calcium import into the mitochondrion)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0046039"(GTP metabolic process)|go:"GO:0046628"(positive regulation of insulin receptor signaling pathway)|go:"GO:0048312"(intracellular distribution of mitochondria)|go:"GO:0051259"(protein complex oligomerization)|go:"GO:0051602"(response to electrical stimulus)|go:"GO:0060041"(retina development in camera-type eye)|go:"GO:0061003"(positive regulation of dendritic spine morphogenesis)|go:"GO:0061025"(membrane fusion)|go:"GO:0070300"(phosphatidic acid binding)|go:"GO:0070584"(mitochondrion morphogenesis)|go:"GO:0071333"(cellular response to glucose stimulus)|go:"GO:0071456"(cellular response to hypoxia)|go:"GO:0090102"(cochlea development)|go:"GO:0090201"(negative regulation of release of cytochrome c from mitochondria)|go:"GO:0090398"(cellular senescence)|go:"GO:0097749"(membrane tubulation)|go:"GO:1900006"(positive regulation of dendrite development)|go:"GO:1900078"(positive regulation of cellular response to insulin stimulus)|go:"GO:1901612"(cardiolipin binding)|go:"GO:1902236"(negative regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway)|go:"GO:1904643"(response to curcumin)|go:"GO:1905232"(cellular response to L-glutamate)|go:"GO:2001243"(negative regulation of intrinsic apoptotic signaling pathway)|interpro:IPR001401(Dynamin, GTPase region)|interpro:IPR022812|interpro:IPR027417|interpro:IPR030381|interpro:IPR033047|mint:Q2TA68|reactome:R-RNO-169911	-	-	-	figure legend:st1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10116(rat-brain-cortex)|taxid:10116(Rattus norvegicus brain cortex)	-	2020/10/30	2020/10/30	rogid:DtE+ZXAZKdCMvUW5K+jXQ5bH07M10116	rogid:VoIXzPJzVZpHSJC0e6S0JpkXnYQ10116	rigid:3wclwrjZRvafcOruQOYnegkn54c	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q5XIE8	uniprotkb:P97838	intact:EBI-15348306|ensembl:ENSRNOP00000023037	intact:EBI-375673|uniprotkb:Q6QQA8|uniprotkb:Q6QQA9	psi-mi:itm2b_rat(display_long)|uniprotkb:Itm2b(gene name)|psi-mi:Itm2b(display_short)|uniprotkb:Immature BRI2(gene name synonym)|uniprotkb:Transmembrane protein BRI(gene name synonym)	psi-mi:dlgp3_rat(display_long)|uniprotkb:Dlgap3(gene name)|psi-mi:Dlgap3(display_short)|uniprotkb:SAP90/PSD-95-associated protein 3(gene name synonym)|uniprotkb:PSD-95/SAP90-binding protein 3(gene name synonym)|uniprotkb:Dap3(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Martins et al. (2018)	imex:IM-28469|pubmed:29476059	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26439741|imex:IM-28469-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSRNOG00000016271(gene)|ensembl:ENSRNOT00000023037(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001540"(amyloid-beta binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0010008"(endosome membrane)|go:"GO:0030660"(Golgi-associated vesicle membrane)|go:"GO:0031301"(integral component of organelle membrane)|go:"GO:0042985"(negative regulation of amyloid precursor protein biosynthetic process)|interpro:IPR007084(BRICHOS)|interpro:IPR040145|mint:Q5XIE8|refseq:NP_001006964.1|rgd:620727	go:"GO:0001540"(amyloid-beta binding)|go:"GO:0005886"(plasma membrane)|go:"GO:0014069"(postsynaptic density)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0023052"(signaling)|go:"GO:0030165"(PDZ domain binding)|go:"GO:0031594"(neuromuscular junction)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043197"(dendritic spine)|go:"GO:0045202"(synapse)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0065003"(protein-containing complex assembly)|go:"GO:0097110"(scaffold protein binding)|go:"GO:0098962"(regulation of postsynaptic neurotransmitter receptor activity)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0098981"(cholinergic synapse)|go:"GO:0099563"(modification of synaptic structure)|go:"GO:0099572"(postsynaptic specialization)|reactome:R-RNO-6794361|rgd:708349|interpro:IPR005026(Guanylate-kinase-associated protein)|mint:P97838|interpro:IPR030526	-	-	-	figure legend:st1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10116(rat-brain-cortex)|taxid:10116(Rattus norvegicus brain cortex)	-	2020/10/30	2020/10/30	rogid:DtE+ZXAZKdCMvUW5K+jXQ5bH07M10116	rogid:jgW6bBCkUv5IztQEQQXrKapRb0w10116	rigid:3wclwrjZRvafcOruQOYnegkn54c	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q5XIE8	uniprotkb:P97837	intact:EBI-15348306|ensembl:ENSRNOP00000023037	intact:EBI-81025	psi-mi:itm2b_rat(display_long)|uniprotkb:Itm2b(gene name)|psi-mi:Itm2b(display_short)|uniprotkb:Immature BRI2(gene name synonym)|uniprotkb:Transmembrane protein BRI(gene name synonym)	psi-mi:dlgp2_rat(display_long)|uniprotkb:Dlgap2(gene name)|psi-mi:Dlgap2(display_short)|uniprotkb:Dap2(gene name synonym)|uniprotkb:SAP90/PSD-95-associated protein 2(gene name synonym)|uniprotkb:PSD-95/SAP90-binding protein 2(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Martins et al. (2018)	imex:IM-28469|pubmed:29476059	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26439741|imex:IM-28469-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSRNOG00000016271(gene)|ensembl:ENSRNOT00000023037(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001540"(amyloid-beta binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0010008"(endosome membrane)|go:"GO:0030660"(Golgi-associated vesicle membrane)|go:"GO:0031301"(integral component of organelle membrane)|go:"GO:0042985"(negative regulation of amyloid precursor protein biosynthetic process)|interpro:IPR007084(BRICHOS)|interpro:IPR040145|mint:Q5XIE8|refseq:NP_001006964.1|rgd:620727	rgd:620224|interpro:IPR005026(Guanylate-kinase-associated protein)|go:"GO:0004385"(guanylate kinase activity)|go:"GO:0005883"(neurofilament)|go:"GO:0007270"(neuron-neuron synaptic transmission)|go:"GO:0014069"(postsynaptic density)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030425"(dendrite)|go:"GO:0043197"(dendritic spine)|go:"GO:0045211"(postsynaptic membrane)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0098962"(regulation of postsynaptic neurotransmitter receptor activity)|go:"GO:0099572"(postsynaptic specialization)|reactome:R-RNO-6794361|go:"GO:0098978"(glutamatergic synapse)|interpro:IPR030525|refseq:NP_446353.2|mint:P97837	-	-	-	figure legend:st1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10116(rat-brain-cortex)|taxid:10116(Rattus norvegicus brain cortex)	-	2020/10/30	2020/10/30	rogid:DtE+ZXAZKdCMvUW5K+jXQ5bH07M10116	rogid:WFFaNSwGhTQ4B4JQBRSuHFFEKh010116	rigid:3wclwrjZRvafcOruQOYnegkn54c	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q5XIE8	uniprotkb:P97836	intact:EBI-15348306|ensembl:ENSRNOP00000023037	intact:EBI-80901|uniprotkb:O54773|uniprotkb:P97841	psi-mi:itm2b_rat(display_long)|uniprotkb:Itm2b(gene name)|psi-mi:Itm2b(display_short)|uniprotkb:Immature BRI2(gene name synonym)|uniprotkb:Transmembrane protein BRI(gene name synonym)	psi-mi:dlgp1_rat(display_long)|uniprotkb:Dlgap1(gene name)|psi-mi:Dlgap1(display_short)|uniprotkb:Gkap(gene name synonym)|uniprotkb:Guanylate kinase-associated protein(gene name synonym)|uniprotkb:SAP90/PSD-95-associated protein 1(gene name synonym)|uniprotkb:PSD-95/SAP90-binding protein 1(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Martins et al. (2018)	imex:IM-28469|pubmed:29476059	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26439741|imex:IM-28469-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSRNOG00000016271(gene)|ensembl:ENSRNOT00000023037(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001540"(amyloid-beta binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0010008"(endosome membrane)|go:"GO:0030660"(Golgi-associated vesicle membrane)|go:"GO:0031301"(integral component of organelle membrane)|go:"GO:0042985"(negative regulation of amyloid precursor protein biosynthetic process)|interpro:IPR007084(BRICHOS)|interpro:IPR040145|mint:Q5XIE8|refseq:NP_001006964.1|rgd:620727	go:"GO:0005886"(plasma membrane)|go:"GO:0007268"(chemical synaptic transmission)|go:"GO:0014069"(postsynaptic density)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0035418"(protein localization to synapse)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045202"(synapse)|go:"GO:0045211"(postsynaptic membrane)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0061136"(regulation of proteasomal protein catabolic process)|go:"GO:0070842"(aggresome assembly)|go:"GO:0098919"(structural constituent of postsynaptic density)|go:"GO:0098962"(regulation of postsynaptic neurotransmitter receptor activity)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099092"(postsynaptic density, intracellular component)|go:"GO:0099562"(maintenance of postsynaptic density structure)|go:"GO:0099572"(postsynaptic specialization)|rcsb pdb:4R0Y|rcsb pdb:5OVC|reactome:R-RNO-6794361|refseq:NP_001291216.1|rgd:620223|interpro:IPR005026(Guanylate-kinase-associated protein)|interpro:IPR030524|refseq:XP_008765652.1|refseq:XP_008765654.1|mint:P97836	-	-	-	figure legend:st1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10116(rat-brain-cortex)|taxid:10116(Rattus norvegicus brain cortex)	-	2020/10/30	2020/10/30	rogid:DtE+ZXAZKdCMvUW5K+jXQ5bH07M10116	rogid:SkbS3bVadWCgL9ZlUsJ3V2tP2GM10116	rigid:3wclwrjZRvafcOruQOYnegkn54c	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q5XIE8	uniprotkb:Q63622	intact:EBI-15348306|ensembl:ENSRNOP00000023037	intact:EBI-396947|uniprotkb:P70548|uniprotkb:Q62939	psi-mi:itm2b_rat(display_long)|uniprotkb:Itm2b(gene name)|psi-mi:Itm2b(display_short)|uniprotkb:Immature BRI2(gene name synonym)|uniprotkb:Transmembrane protein BRI(gene name synonym)	psi-mi:dlg2_rat(display_long)|uniprotkb:Dlg2(gene name)|psi-mi:Dlg2(display_short)|uniprotkb:Postsynaptic density protein PSD-93(gene name synonym)|uniprotkb:Channel-associated protein of synapse-110(gene name synonym)|uniprotkb:Dlgh2(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Martins et al. (2018)	imex:IM-28469|pubmed:29476059	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26439741|imex:IM-28469-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSRNOG00000016271(gene)|ensembl:ENSRNOT00000023037(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001540"(amyloid-beta binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0010008"(endosome membrane)|go:"GO:0030660"(Golgi-associated vesicle membrane)|go:"GO:0031301"(integral component of organelle membrane)|go:"GO:0042985"(negative regulation of amyloid precursor protein biosynthetic process)|interpro:IPR007084(BRICHOS)|interpro:IPR040145|mint:Q5XIE8|refseq:NP_001006964.1|rgd:620727	rgd:619895|refseq:NP_071618.1|interpro:IPR008144(Guanylate kinase)|interpro:IPR008145(Guanylate kinase/L-type calcium channel region)|interpro:IPR020590|interpro:IPR016313("Membrane-associated guanylate kinase (MAGUK) scaffold protein")|interpro:IPR019590|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR019583|interpro:IPR001452(Src homology-3)|interpro:IPR027417|go:"GO:0019233"(sensory perception of pain)|go:"GO:0019900"(kinase binding)|go:"GO:0019903"(protein phosphatase binding)|go:"GO:0030054"(cell junction)|go:"GO:0030165"(PDZ domain binding)|go:"GO:0030425"(dendrite)|go:"GO:0030672"(synaptic vesicle membrane)|go:"GO:0031594"(neuromuscular junction)|go:"GO:0035865"(cellular response to potassium ion)|go:"GO:0043005"(neuron projection)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043113"(receptor clustering)|go:"GO:0043204"(perikaryon)|go:"GO:0044224"(juxtaparanode region of axon)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045161"(neuronal ion channel clustering)|go:"GO:0045197"(establishment or maintenance of epithelial cell apical/basal polarity)|go:"GO:0045211"(postsynaptic membrane)|go:"GO:0097120"(receptor localization to synapse)|go:"GO:0098609"(cell-cell adhesion)|go:"GO:0098839"(postsynaptic density membrane)|go:"GO:0098919"(structural constituent of postsynaptic density)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099031"(anchored component of postsynaptic density membrane)|go:"GO:0099641"(anterograde axonal protein transport)|go:"GO:0099642"(retrograde axonal protein transport)|go:"GO:0099645"(neurotransmitter receptor localization to postsynaptic specialization membrane)|go:"GO:1904115"(axon cytoplasm)|rcsb pdb:4H11|reactome:R-RNO-438066|reactome:R-RNO-5673001|reactome:R-RNO-6794361|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0005737"(cytoplasm)|go:"GO:0007268"(chemical synaptic transmission)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0014069"(postsynaptic density)|go:"GO:0016020"(membrane)|mint:Q63622|interpro:IPR035759|interpro:IPR036028|interpro:IPR036034	-	-	-	figure legend:st1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10116(rat-brain-cortex)|taxid:10116(Rattus norvegicus brain cortex)	-	2020/10/30	2020/10/30	rogid:DtE+ZXAZKdCMvUW5K+jXQ5bH07M10116	rogid:Vy8yJ82tI5P41sQz9pRlgRK0ugI10116	rigid:3wclwrjZRvafcOruQOYnegkn54c	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q5XIE8	uniprotkb:Q63342	intact:EBI-15348306|ensembl:ENSRNOP00000023037	intact:EBI-26438474	psi-mi:itm2b_rat(display_long)|uniprotkb:Itm2b(gene name)|psi-mi:Itm2b(display_short)|uniprotkb:Immature BRI2(gene name synonym)|uniprotkb:Transmembrane protein BRI(gene name synonym)	psi-mi:m2gd_rat(display_long)|uniprotkb:Dmgdh(gene name)|psi-mi:Dmgdh(display_short)|uniprotkb:ME2GLYDH(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Martins et al. (2018)	imex:IM-28469|pubmed:29476059	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26439741|imex:IM-28469-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSRNOG00000016271(gene)|ensembl:ENSRNOT00000023037(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001540"(amyloid-beta binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0010008"(endosome membrane)|go:"GO:0030660"(Golgi-associated vesicle membrane)|go:"GO:0031301"(integral component of organelle membrane)|go:"GO:0042985"(negative regulation of amyloid precursor protein biosynthetic process)|interpro:IPR007084(BRICHOS)|interpro:IPR040145|mint:Q5XIE8|refseq:NP_001006964.1|rgd:620727	go:"GO:0005542"(folic acid binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0006579"(amino-acid betaine catabolic process)|go:"GO:0016491"(oxidoreductase activity)|go:"GO:0019695"(choline metabolic process)|go:"GO:0035999"(tetrahydrofolate interconversion)|go:"GO:0042426"(choline catabolic process)|go:"GO:0047865"(dimethylglycine dehydrogenase activity)|go:"GO:0050660"(flavin adenine dinucleotide binding)|rcsb pdb:4P9S|rcsb pdb:4PAA|rcsb pdb:4PAB|reactome:R-RNO-6798163|mint:Q63342|interpro:IPR006076(FAD dependent oxidoreductase)|interpro:IPR036188|interpro:IPR032503|interpro:IPR013977(Glycine cleavage T-protein, C-terminal barrel)|interpro:IPR006222(Glycine cleavage T-protein, N-terminal)|interpro:IPR029043|interpro:IPR027266|rgd:620453	-	-	-	figure legend:st1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10116(rat-brain-cortex)|taxid:10116(Rattus norvegicus brain cortex)	-	2020/10/30	2020/10/30	rogid:DtE+ZXAZKdCMvUW5K+jXQ5bH07M10116	rogid:VtSaGbt5uusDPTfkoGVH7MAgQkE10116	rigid:3wclwrjZRvafcOruQOYnegkn54c	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q5XIE8	uniprotkb:P32551	intact:EBI-15348306|ensembl:ENSRNOP00000023037	intact:EBI-917272|uniprotkb:Q5XIR3|ensembl:ENSRNOP00000021514	psi-mi:itm2b_rat(display_long)|uniprotkb:Itm2b(gene name)|psi-mi:Itm2b(display_short)|uniprotkb:Immature BRI2(gene name synonym)|uniprotkb:Transmembrane protein BRI(gene name synonym)	psi-mi:qcr2_rat(display_long)|uniprotkb:Ubiquinol-cytochrome-c reductase complex core protein 2(gene name synonym)|uniprotkb:Core protein II(gene name synonym)|uniprotkb:Complex III subunit 2(gene name synonym)|uniprotkb:Uqcrc2(gene name)|psi-mi:Uqcrc2(display_short)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Martins et al. (2018)	imex:IM-28469|pubmed:29476059	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26439741|imex:IM-28469-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSRNOG00000016271(gene)|ensembl:ENSRNOT00000023037(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001540"(amyloid-beta binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0010008"(endosome membrane)|go:"GO:0030660"(Golgi-associated vesicle membrane)|go:"GO:0031301"(integral component of organelle membrane)|go:"GO:0042985"(negative regulation of amyloid precursor protein biosynthetic process)|interpro:IPR007084(BRICHOS)|interpro:IPR040145|mint:Q5XIE8|refseq:NP_001006964.1|rgd:620727	rgd:1359150|refseq:NP_001006971.1|ensembl:ENSRNOG00000036742(gene)|ensembl:ENSRNOT00000021514(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005750"(mitochondrial respiratory chain complex III)|go:"GO:0005751"(mitochondrial respiratory chain complex IV)|go:"GO:0006508"(proteolysis)|go:"GO:0042493"|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0046872"(metal ion binding)|interpro:IPR001431(Peptidase M16, zinc-binding site)|interpro:IPR007863(Peptidase M16, C-terminal)|interpro:IPR011249(Metalloenzyme, LuxS/M16 peptidase-like, metal-binding)|interpro:IPR011765(Peptidase M16, N-terminal)|mint:P32551|reactome:R-RNO-611105	-	-	-	figure legend:st1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10116(rat-brain-cortex)|taxid:10116(Rattus norvegicus brain cortex)	-	2020/10/30	2020/10/30	rogid:DtE+ZXAZKdCMvUW5K+jXQ5bH07M10116	rogid:HvF0+1g/n1jgbf7314R6bHEWXa810116	rigid:3wclwrjZRvafcOruQOYnegkn54c	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q5XIE8	uniprotkb:Q03114	intact:EBI-15348306|ensembl:ENSRNOP00000023037	intact:EBI-2008531|ensembl:ENSRNOP00000011052	psi-mi:itm2b_rat(display_long)|uniprotkb:Itm2b(gene name)|psi-mi:Itm2b(display_short)|uniprotkb:Immature BRI2(gene name synonym)|uniprotkb:Transmembrane protein BRI(gene name synonym)	psi-mi:cdk5_rat(display_long)|uniprotkb:Cdk5(gene name)|psi-mi:Cdk5(display_short)|uniprotkb:Cell division protein kinase 5(gene name synonym)|uniprotkb:Tau protein kinase II catalytic subunit(gene name synonym)|uniprotkb:Serine/threonine-protein kinase PSSALRE(gene name synonym)|uniprotkb:Cdkn5(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Martins et al. (2018)	imex:IM-28469|pubmed:29476059	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26439741|imex:IM-28469-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSRNOG00000016271(gene)|ensembl:ENSRNOT00000023037(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001540"(amyloid-beta binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0010008"(endosome membrane)|go:"GO:0030660"(Golgi-associated vesicle membrane)|go:"GO:0031301"(integral component of organelle membrane)|go:"GO:0042985"(negative regulation of amyloid precursor protein biosynthetic process)|interpro:IPR007084(BRICHOS)|interpro:IPR040145|mint:Q5XIE8|refseq:NP_001006964.1|rgd:620727	rgd:70514|refseq:NP_543161.1|dip:DIP-29351N|ensembl:ENSRNOG00000008017(gene)|ensembl:ENSRNOT00000011052(transcript)|go:"GO:0000083"(regulation of transcription involved in G1/S transition of mitotic cell cycle)|go:"GO:0001764"(neuron migration)|go:"GO:0001934"(positive regulation of protein phosphorylation)|go:"GO:0001963"(synaptic transmission, dopaminergic)|go:"GO:0002039"(p53 binding)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0004693"(cyclin-dependent protein serine/threonine kinase activity)|go:"GO:0005176"(ErbB-2 class receptor binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005886"(plasma membrane)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006887"(exocytosis)|go:"GO:0006913"(nucleocytoplasmic transport)|go:"GO:0006915"(apoptotic process)|go:"GO:0007005"(mitochondrion organization)|go:"GO:0007160"(cell-matrix adhesion)|go:"GO:0007409"(axonogenesis)|go:"GO:0007416"(synapse assembly)|go:"GO:0007417"(central nervous system development)|go:"GO:0007519"(skeletal muscle tissue development)|go:"GO:0008045"(motor neuron axon guidance)|go:"GO:0008092"(cytoskeletal protein binding)|go:"GO:0008306"(associative learning)|go:"GO:0008542"(visual learning)|go:"GO:0009611"(response to wounding)|go:"GO:0014044"(Schwann cell development)|go:"GO:0014069"(postsynaptic density)|go:"GO:0016020"(membrane)|go:"GO:0016301"(kinase activity)|go:"GO:0016310"(phosphorylation)|go:"GO:0016477"(cell migration)|go:"GO:0016533"(protein kinase 5 complex)|go:"GO:0016572"(histone phosphorylation)|go:"GO:0018105"(peptidyl-serine phosphorylation)|go:"GO:0018107"(peptidyl-threonine phosphorylation)|go:"GO:0019233"(sensory perception of pain)|go:"GO:0019901"(protein kinase binding)|go:"GO:0021537"(telencephalon development)|go:"GO:0021549"(cerebellum development)|go:"GO:0021695"(cerebellar cortex development)|go:"GO:0021697"(cerebellar cortex formation)|go:"GO:0021766"(hippocampus development)|go:"GO:0021819"(layer formation in cerebral cortex)|go:"GO:0021954"(central nervous system neuron development)|go:"GO:0021987"(cerebral cortex development)|go:"GO:0022038"(corpus callosum development)|go:"GO:0030027"(lamellipodium)|go:"GO:0030054"(cell junction)|go:"GO:0030175"(filopodium)|go:"GO:0030182"(neuron differentiation)|go:"GO:0030334"(regulation of cell migration)|go:"GO:0030424"(axon)|go:"GO:0030425"(dendrite)|go:"GO:0030426"(growth cone)|go:"GO:0030517"(negative regulation of axon extension)|go:"GO:0030549"(acetylcholine receptor activator activity)|go:"GO:0030866"(cortical actin cytoskeleton organization)|go:"GO:0030900"(forebrain development)|go:"GO:0031175"(neuron projection development)|go:"GO:0031397"(negative regulation of protein ubiquitination)|go:"GO:0031594"(neuromuscular junction)|go:"GO:0031914"(negative regulation of synaptic plasticity)|go:"GO:0032092"(positive regulation of protein binding)|go:"GO:0032801"(receptor catabolic process)|go:"GO:0034352"(positive regulation of glial cell apoptotic process)|go:"GO:0035249"(synaptic transmission, glutamatergic)|go:"GO:0035418"(protein localization to synapse)|go:"GO:0042220"(response to cocaine)|go:"GO:0042501"(serine phosphorylation of STAT protein)|go:"GO:0043005"(neuron projection)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043113"(receptor clustering)|go:"GO:0043125"(ErbB-3 class receptor binding)|go:"GO:0043204"(perikaryon)|go:"GO:0043525"(positive regulation of neuron apoptotic process)|go:"GO:0045055"(regulated exocytosis)|go:"GO:0045786"(negative regulation of cell cycle)|go:"GO:0045860"(positive regulation of protein kinase activity)|go:"GO:0045861"(negative regulation of proteolysis)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045956"(positive regulation of calcium ion-dependent exocytosis)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0046826"(negative regulation of protein export from nucleus)|go:"GO:0046875"(ephrin receptor binding)|go:"GO:0048148"(behavioral response to cocaine)|go:"GO:0048167"(regulation of synaptic plasticity)|go:"GO:0048488"(synaptic vesicle endocytosis)|go:"GO:0048489"(synaptic vesicle transport)|go:"GO:0048511"(rhythmic process)|go:"GO:0048675"(axon extension)|go:"GO:0048709"(oligodendrocyte differentiation)|go:"GO:0048812"(neuron projection morphogenesis)|go:"GO:0048813"(dendrite morphogenesis)|go:"GO:0050321"(tau-protein kinase activity)|go:"GO:0051301"(cell division)|go:"GO:0051402"(neuron apoptotic process)|go:"GO:0051879"(Hsp90 protein binding)|go:"GO:0051966"(regulation of synaptic transmission, glutamatergic)|go:"GO:0060078"(regulation of postsynaptic membrane potential)|go:"GO:0060079"(excitatory postsynaptic potential)|go:"GO:0061001"(regulation of dendritic spine morphogenesis)|go:"GO:0070509"(calcium ion import)|go:"GO:0090314"(positive regulation of protein targeting to membrane)|go:"GO:0098685"(Schaffer collateral - CA1 synapse)|go:"GO:0098793"(presynapse)|go:"GO:0098794"(postsynapse)|go:"GO:0098883"(synapse pruning)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099533"(positive regulation of presynaptic cytosolic calcium concentration)|go:"GO:0099635"(voltage-gated calcium channel activity involved in positive regulation of presynaptic cytosolic calcium levels)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:1901215"(negative regulation of neuron death)|go:"GO:1901216"(positive regulation of neuron death)|go:"GO:1901387"(positive regulation of voltage-gated calcium channel activity)|go:"GO:1903076"(regulation of protein localization to plasma membrane)|go:"GO:1904646"(cellular response to amyloid-beta)|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|mint:Q03114|reactome:R-RNO-180024|reactome:R-RNO-399956|reactome:R-RNO-6804756	-	-	-	figure legend:st1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10116(rat-brain-cortex)|taxid:10116(Rattus norvegicus brain cortex)	-	2020/10/30	2020/10/30	rogid:DtE+ZXAZKdCMvUW5K+jXQ5bH07M10116	rogid:I/vFYZi6Vs4Y+Itk5sPLBj+QJxk10116	rigid:3wclwrjZRvafcOruQOYnegkn54c	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q5XIE8	uniprotkb:P31722	intact:EBI-15348306|ensembl:ENSRNOP00000023037	intact:EBI-15185680|uniprotkb:Q5RJZ8	psi-mi:itm2b_rat(display_long)|uniprotkb:Itm2b(gene name)|psi-mi:Itm2b(display_short)|uniprotkb:Immature BRI2(gene name synonym)|uniprotkb:Transmembrane protein BRI(gene name synonym)	psi-mi:c1qc_rat(display_long)|uniprotkb:C1qc(gene name)|psi-mi:C1qc(display_short)|uniprotkb:C1qg(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Martins et al. (2018)	imex:IM-28469|pubmed:29476059	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26439741|imex:IM-28469-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSRNOG00000016271(gene)|ensembl:ENSRNOT00000023037(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001540"(amyloid-beta binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0010008"(endosome membrane)|go:"GO:0030660"(Golgi-associated vesicle membrane)|go:"GO:0031301"(integral component of organelle membrane)|go:"GO:0042985"(negative regulation of amyloid precursor protein biosynthetic process)|interpro:IPR007084(BRICHOS)|interpro:IPR040145|mint:Q5XIE8|refseq:NP_001006964.1|rgd:620727	mint:P31722|go:"GO:0005576"(extracellular region)|go:"GO:0005581"(collagen trimer)|go:"GO:0006958"(complement activation, classical pathway)|go:"GO:0030853"(negative regulation of granulocyte differentiation)|go:"GO:0045087"(innate immune response)|go:"GO:0045202"(synapse)|go:"GO:0045650"(negative regulation of macrophage differentiation)|go:"GO:0098794"(postsynapse)|go:"GO:0098883"(synapse pruning)|reactome:R-RNO-173623|reactome:R-RNO-977606|reactome:R-RNO-166663|refseq:NP_001008524.1|interpro:IPR001073(Complement C1q protein)|interpro:IPR008160(Collagen triple helix repeat)|interpro:IPR008983(Tumour necrosis factor-like)|rgd:1306828	-	-	-	figure legend:st1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10116(rat-brain-cortex)|taxid:10116(Rattus norvegicus brain cortex)	-	2020/10/30	2020/10/30	rogid:DtE+ZXAZKdCMvUW5K+jXQ5bH07M10116	rogid:JEQN8sBWiMYg6oRSq6mKcKyiHa410116	rigid:3wclwrjZRvafcOruQOYnegkn54c	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q5XIE8	uniprotkb:Q99P82	intact:EBI-15348306|ensembl:ENSRNOP00000023037	intact:EBI-26438451	psi-mi:itm2b_rat(display_long)|uniprotkb:Itm2b(gene name)|psi-mi:Itm2b(display_short)|uniprotkb:Immature BRI2(gene name synonym)|uniprotkb:Transmembrane protein BRI(gene name synonym)	psi-mi:cld11_rat(display_long)|uniprotkb:Cldn11(gene name)|psi-mi:Cldn11(display_short)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Martins et al. (2018)	imex:IM-28469|pubmed:29476059	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26439741|imex:IM-28469-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSRNOG00000016271(gene)|ensembl:ENSRNOT00000023037(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001540"(amyloid-beta binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0010008"(endosome membrane)|go:"GO:0030660"(Golgi-associated vesicle membrane)|go:"GO:0031301"(integral component of organelle membrane)|go:"GO:0042985"(negative regulation of amyloid precursor protein biosynthetic process)|interpro:IPR007084(BRICHOS)|interpro:IPR040145|mint:Q5XIE8|refseq:NP_001006964.1|rgd:620727	go:"GO:0005198"(structural molecule activity)|go:"GO:0005883"(neurofilament)|go:"GO:0005886"(plasma membrane)|go:"GO:0005923"(bicellular tight junction)|go:"GO:0007155"(cell adhesion)|go:"GO:0007283"(spermatogenesis)|go:"GO:0008366"(axon ensheathment)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016338"(calcium-independent cell-cell adhesion via plasma membrane cell-adhesion molecules)|go:"GO:0030424"(axon)|go:"GO:0042802"(identical protein binding)|go:"GO:0045178"(basal part of cell)|go:"GO:0070160"(tight junction)|go:"GO:0070830"(bicellular tight junction assembly)|go:"GO:0120192"(tight junction assembly)|mint:Q99P82|interpro:IPR006187(Claudin)|interpro:IPR003555(Claudin-11)|interpro:IPR017974|interpro:IPR004031(PMP-22/EMP/MP20/Claudin)|rgd:71081	-	-	-	figure legend:st1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10116(rat-brain-cortex)|taxid:10116(Rattus norvegicus brain cortex)	-	2020/10/30	2020/10/30	rogid:DtE+ZXAZKdCMvUW5K+jXQ5bH07M10116	rogid:HHJQsheYpBnxwSzdTBj2Hpsxa+g10116	rigid:3wclwrjZRvafcOruQOYnegkn54c	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q5XIE8	uniprotkb:Q8VHF5	intact:EBI-15348306|ensembl:ENSRNOP00000023037	intact:EBI-349285	psi-mi:itm2b_rat(display_long)|uniprotkb:Itm2b(gene name)|psi-mi:Itm2b(display_short)|uniprotkb:Immature BRI2(gene name synonym)|uniprotkb:Transmembrane protein BRI(gene name synonym)	psi-mi:cisy_rat(display_long)|uniprotkb:Cs(gene name)|psi-mi:Cs(display_short)|uniprotkb:"Citrate (Si)-synthase"(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Martins et al. (2018)	imex:IM-28469|pubmed:29476059	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26439741|imex:IM-28469-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSRNOG00000016271(gene)|ensembl:ENSRNOT00000023037(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001540"(amyloid-beta binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0010008"(endosome membrane)|go:"GO:0030660"(Golgi-associated vesicle membrane)|go:"GO:0031301"(integral component of organelle membrane)|go:"GO:0042985"(negative regulation of amyloid precursor protein biosynthetic process)|interpro:IPR007084(BRICHOS)|interpro:IPR040145|mint:Q5XIE8|refseq:NP_001006964.1|rgd:620727	rgd:620330|refseq:NP_570111.1|interpro:IPR016142(Citrate synthase-like, large alpha subdomain)|interpro:IPR002020(Citrate synthase-like)|interpro:IPR019810|interpro:IPR010109(Citrate synthase, eukaryotic)|go:"GO:0004108"("citrate (Si)-synthase activity")|go:"GO:0005739"(mitochondrion)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0005975"(carbohydrate metabolic process)|go:"GO:0006084"(acetyl-CoA metabolic process)|go:"GO:0006099"(tricarboxylic acid cycle)|go:"GO:0006101"(citrate metabolic process)|go:"GO:0006107"(oxaloacetate metabolic process)|go:"GO:0046912"(acyltransferase, acyl groups converted into alkyl on transfer)|reactome:R-RNO-71403|interpro:IPR016143(Citrate synthase-like, small alpha subdomain)|mint:Q8VHF5|interpro:IPR036969	-	-	-	figure legend:st1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10116(rat-brain-cortex)|taxid:10116(Rattus norvegicus brain cortex)	-	2020/10/30	2020/10/30	rogid:DtE+ZXAZKdCMvUW5K+jXQ5bH07M10116	rogid:3c3FZwuqQofmxnE7JYrd/zmEHec10116	rigid:3wclwrjZRvafcOruQOYnegkn54c	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q5XIE8	uniprotkb:B2RYL1	intact:EBI-15348306|ensembl:ENSRNOP00000023037	intact:EBI-22249831	psi-mi:itm2b_rat(display_long)|uniprotkb:Itm2b(gene name)|psi-mi:Itm2b(display_short)|uniprotkb:Immature BRI2(gene name synonym)|uniprotkb:Transmembrane protein BRI(gene name synonym)	psi-mi:derpc_rat(display_long)|uniprotkb:Derpc(gene name)|psi-mi:Derpc(display_short)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Martins et al. (2018)	imex:IM-28469|pubmed:29476059	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26439741|imex:IM-28469-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSRNOG00000016271(gene)|ensembl:ENSRNOT00000023037(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001540"(amyloid-beta binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0010008"(endosome membrane)|go:"GO:0030660"(Golgi-associated vesicle membrane)|go:"GO:0031301"(integral component of organelle membrane)|go:"GO:0042985"(negative regulation of amyloid precursor protein biosynthetic process)|interpro:IPR007084(BRICHOS)|interpro:IPR040145|mint:Q5XIE8|refseq:NP_001006964.1|rgd:620727	go:"GO:0005634"(nucleus)|mint:B2RYL1	-	-	-	figure legend:st1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10116(rat-brain-cortex)|taxid:10116(Rattus norvegicus brain cortex)	-	2020/10/30	2020/10/30	rogid:DtE+ZXAZKdCMvUW5K+jXQ5bH07M10116	rogid:i4m7jOAxFwxFFfb/Bvlwyacopyw10116	rigid:3wclwrjZRvafcOruQOYnegkn54c	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q5XIE8	uniprotkb:B0K020	intact:EBI-15348306|ensembl:ENSRNOP00000023037	intact:EBI-26438432|ensembl:ENSRNOP00000000749	psi-mi:itm2b_rat(display_long)|uniprotkb:Itm2b(gene name)|psi-mi:Itm2b(display_short)|uniprotkb:Immature BRI2(gene name synonym)|uniprotkb:Transmembrane protein BRI(gene name synonym)	psi-mi:cisd1_rat(display_long)|uniprotkb:Cisd1(gene name)|psi-mi:Cisd1(display_short)|uniprotkb:MitoNEET(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Martins et al. (2018)	imex:IM-28469|pubmed:29476059	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26439741|imex:IM-28469-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSRNOG00000016271(gene)|ensembl:ENSRNOT00000023037(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001540"(amyloid-beta binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0010008"(endosome membrane)|go:"GO:0030660"(Golgi-associated vesicle membrane)|go:"GO:0031301"(integral component of organelle membrane)|go:"GO:0042985"(negative regulation of amyloid precursor protein biosynthetic process)|interpro:IPR007084(BRICHOS)|interpro:IPR040145|mint:Q5XIE8|refseq:NP_001006964.1|rgd:620727	ensembl:ENSRNOG00000000610(gene)|ensembl:ENSRNOT00000000749(transcript)|go:"GO:0005739"(mitochondrion)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0032473"(cytoplasmic side of mitochondrial outer membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0043457"(regulation of cellular respiration)|go:"GO:0046872"(metal ion binding)|go:"GO:0051537"(2 iron, 2 sulfur cluster binding)|interpro:IPR018967|interpro:IPR019610|interpro:IPR042216|mint:B0K020|refseq:NP_001099855.1|rgd:1309529	-	-	-	figure legend:st1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10116(rat-brain-cortex)|taxid:10116(Rattus norvegicus brain cortex)	-	2020/10/30	2020/10/30	rogid:DtE+ZXAZKdCMvUW5K+jXQ5bH07M10116	rogid:LkpYoubjReINX2CH1FLkvus2ntc10116	rigid:3wclwrjZRvafcOruQOYnegkn54c	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q5XIE8	uniprotkb:P67874	intact:EBI-15348306|ensembl:ENSRNOP00000023037	intact:EBI-348189|ensembl:ENSRNOP00000001123|ensembl:ENSRNOP00000068429|uniprotkb:P07312|uniprotkb:P13862	psi-mi:itm2b_rat(display_long)|uniprotkb:Itm2b(gene name)|psi-mi:Itm2b(display_short)|uniprotkb:Immature BRI2(gene name synonym)|uniprotkb:Transmembrane protein BRI(gene name synonym)	psi-mi:csk2b_rat(display_long)|uniprotkb:Phosvitin(gene name synonym)|uniprotkb:Csnk2b(gene name)|psi-mi:Csnk2b(display_short)|uniprotkb:Ck2n(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Martins et al. (2018)	imex:IM-28469|pubmed:29476059	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26439741|imex:IM-28469-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSRNOG00000016271(gene)|ensembl:ENSRNOT00000023037(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001540"(amyloid-beta binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0010008"(endosome membrane)|go:"GO:0030660"(Golgi-associated vesicle membrane)|go:"GO:0031301"(integral component of organelle membrane)|go:"GO:0042985"(negative regulation of amyloid precursor protein biosynthetic process)|interpro:IPR007084(BRICHOS)|interpro:IPR040145|mint:Q5XIE8|refseq:NP_001006964.1|rgd:620727	reactome:R-RNO-8939243|reactome:R-RNO-8948751|reactome:R-RNO-8934903|ensembl:ENSRNOG00000000847(gene)|ensembl:ENSRNOT00000001123(transcript)|ensembl:ENSRNOT00000076528(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0003682"(chromatin binding)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0005929"(cilium)|go:"GO:0005956"(protein kinase CK2 complex)|go:"GO:0010862"(positive regulation of pathway-restricted SMAD protein phosphorylation)|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0016363"(nuclear matrix)|go:"GO:0018107"(peptidyl-threonine phosphorylation)|go:"GO:0080163"(regulation of protein serine/threonine phosphatase activity)|go:"GO:0097421"(liver regeneration)|go:"GO:0098685"(Schaffer collateral - CA1 synapse)|go:"GO:0019887"(protein kinase regulator activity)|go:"GO:0098794"(postsynapse)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0099170"(postsynaptic modulation of chemical synaptic transmission)|interpro:IPR000704(Casein kinase II, regulatory subunit)|interpro:IPR016149(Casein kinase II, regulatory subunit, alpha-helical)|interpro:IPR035991|mint:P67874|rcsb pdb:2R6M|go:"GO:0031519"(PcG protein complex)|go:"GO:0032927"(positive regulation of activin receptor signaling pathway)|go:"GO:0033211"(adiponectin-activated signaling pathway)|go:"GO:0033574"(response to testosterone)|go:"GO:0042802"(identical protein binding)|go:"GO:0042995"(cell projection)|go:"GO:0043021"(ribonucleoprotein complex binding)|go:"GO:0043537"(negative regulation of blood vessel endothelial cell migration)|go:"GO:0046872"(metal ion binding)|go:"GO:0061154"(endothelial tube morphogenesis)|reactome:R-RNO-1483191|reactome:R-RNO-201688|reactome:R-RNO-2514853|reactome:R-RNO-445144|reactome:R-RNO-6798695|reactome:R-RNO-6804756|reactome:R-RNO-6814122|rgd:619978|refseq:NP_001030315.1|refseq:NP_112283.1	-	-	-	figure legend:st1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10116(rat-brain-cortex)|taxid:10116(Rattus norvegicus brain cortex)	-	2020/10/30	2020/10/30	rogid:DtE+ZXAZKdCMvUW5K+jXQ5bH07M10116	rogid:ZTHJjCqHg2dE7B+WoSU28VSMuPg10116	rigid:3wclwrjZRvafcOruQOYnegkn54c	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q5XIE8	uniprotkb:P27791	intact:EBI-15348306|ensembl:ENSRNOP00000023037	intact:EBI-917032|uniprotkb:Q6UA68	psi-mi:itm2b_rat(display_long)|uniprotkb:Itm2b(gene name)|psi-mi:Itm2b(display_short)|uniprotkb:Immature BRI2(gene name synonym)|uniprotkb:Transmembrane protein BRI(gene name synonym)	psi-mi:kapca_rat(display_long)|uniprotkb:Prkaca(gene name)|psi-mi:Prkaca(display_short)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Martins et al. (2018)	imex:IM-28469|pubmed:29476059	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26439741|imex:IM-28469-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSRNOG00000016271(gene)|ensembl:ENSRNOT00000023037(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001540"(amyloid-beta binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0010008"(endosome membrane)|go:"GO:0030660"(Golgi-associated vesicle membrane)|go:"GO:0031301"(integral component of organelle membrane)|go:"GO:0042985"(negative regulation of amyloid precursor protein biosynthetic process)|interpro:IPR007084(BRICHOS)|interpro:IPR040145|mint:Q5XIE8|refseq:NP_001006964.1|rgd:620727	rgd:3389|mint:P27791|dip:DIP-37312N|go:"GO:0000287"(magnesium ion binding)|go:"GO:0001669"(acrosomal vesicle)|go:"GO:0001707"(mesoderm formation)|go:"GO:0001843"(neural tube closure)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0004679"(AMP-activated protein kinase activity)|go:"GO:0004691"(cAMP-dependent protein kinase activity)|go:"GO:0004712"(protein serine/threonine/tyrosine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005952"(cAMP-dependent protein kinase complex)|go:"GO:0006397"(mRNA processing)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0010737"(protein kinase A signaling)|go:"GO:0016020"(membrane)|go:"GO:0016607"(nuclear speck)|go:"GO:0018105"(peptidyl-serine phosphorylation)|go:"GO:0018107"(peptidyl-threonine phosphorylation)|go:"GO:0019901"(protein kinase binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030145"(manganese ion binding)|go:"GO:0031267"(small GTPase binding)|go:"GO:0031594"(neuromuscular junction)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034237"(protein kinase A regulatory subunit binding)|go:"GO:0034605"(cellular response to heat)|go:"GO:0036126"(sperm flagellum)|go:"GO:0042747"(circadian sleep/wake cycle, REM sleep)|go:"GO:0043005"(neuron projection)|go:"GO:0043197"(dendritic spine)|go:"GO:0043457"(regulation of cellular respiration)|go:"GO:0044853"(plasma membrane raft)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045667"(regulation of osteoblast differentiation)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0046827"(positive regulation of protein export from nucleus)|go:"GO:0048240"(sperm capacitation)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0048792"(spontaneous exocytosis of neurotransmitter)|go:"GO:0050804"(modulation of chemical synaptic transmission)|go:"GO:0051447"(negative regulation of meiotic cell cycle)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0051966"(regulation of synaptic transmission, glutamatergic)|go:"GO:0061136"(regulation of proteasomal protein catabolic process)|go:"GO:0070613"(regulation of protein processing)|go:"GO:0071333"(cellular response to glucose stimulus)|go:"GO:0071374"(cellular response to parathyroid hormone stimulus)|go:"GO:0097225"(sperm midpiece)|go:"GO:0097546"(ciliary base)|go:"GO:0098793"(presynapse)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:1901621"(negative regulation of smoothened signaling pathway involved in dorsal/ventral neural tube patterning)|go:"GO:2000810"(regulation of bicellular tight junction assembly)|interpro:IPR000719(Protein kinase, core)|interpro:IPR000961(Protein kinase, C-terminal)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR044109|reactome:R-RNO-163615|reactome:R-RNO-164378|reactome:R-RNO-180024|reactome:R-RNO-2565942|reactome:R-RNO-380259|reactome:R-RNO-380270|reactome:R-RNO-380284|reactome:R-RNO-380320|reactome:R-RNO-381676|reactome:R-RNO-392517|reactome:R-RNO-422356|reactome:R-RNO-432040|reactome:R-RNO-4420097|reactome:R-RNO-442720|reactome:R-RNO-512988|reactome:R-RNO-5578775|reactome:R-RNO-5610785|reactome:R-RNO-5610787|reactome:R-RNO-5620912|reactome:R-RNO-5687128|reactome:R-RNO-8853659|reactome:R-RNO-8854518|reactome:R-RNO-8963896|reactome:R-RNO-983231	-	-	-	figure legend:st1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10116(rat-brain-cortex)|taxid:10116(Rattus norvegicus brain cortex)	-	2020/10/30	2020/10/30	rogid:DtE+ZXAZKdCMvUW5K+jXQ5bH07M10116	rogid:vfm7xEYQfzaRDobnpGQh57Kpd6Q10116	rigid:3wclwrjZRvafcOruQOYnegkn54c	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q5XIE8	uniprotkb:P29066	intact:EBI-15348306|ensembl:ENSRNOP00000023037	intact:EBI-4303019|ensembl:ENSRNOP00000046069	psi-mi:itm2b_rat(display_long)|uniprotkb:Itm2b(gene name)|psi-mi:Itm2b(display_short)|uniprotkb:Immature BRI2(gene name synonym)|uniprotkb:Transmembrane protein BRI(gene name synonym)	psi-mi:arrb1_rat(display_long)|uniprotkb:Arrb1(gene name)|psi-mi:Arrb1(display_short)|uniprotkb:Arrestin beta-1(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Martins et al. (2018)	imex:IM-28469|pubmed:29476059	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26439741|imex:IM-28469-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSRNOG00000016271(gene)|ensembl:ENSRNOT00000023037(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001540"(amyloid-beta binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0010008"(endosome membrane)|go:"GO:0030660"(Golgi-associated vesicle membrane)|go:"GO:0031301"(integral component of organelle membrane)|go:"GO:0042985"(negative regulation of amyloid precursor protein biosynthetic process)|interpro:IPR007084(BRICHOS)|interpro:IPR040145|mint:Q5XIE8|refseq:NP_001006964.1|rgd:620727	rgd:2156|refseq:NP_037042.1|interpro:IPR011022(Arrestin-like, C-terminal)|interpro:IPR014752(Arrestin, C-terminal)|interpro:IPR014753(Arrestin, N-terminal)|interpro:IPR014756(Immunoglobulin E-set)|interpro:IPR017864|mint:P29066|rcsb pdb:4JQI|rcsb pdb:6KL7|rcsb pdb:6U1N|reactome:R-RNO-418555|reactome:R-RNO-432720|reactome:R-RNO-432722|reactome:R-RNO-456926|reactome:R-RNO-5635838|reactome:R-RNO-5674135|reactome:R-RNO-5689880|reactome:R-RNO-8856825|reactome:R-RNO-8856828|interpro:IPR011021(Arrestin-like, N-terminal)|ensembl:ENSRNOG00000030404(gene)|ensembl:ENSRNOT00000043554(transcript)|go:"GO:0000187"(obsolete activation of MAPK activity)|go:"GO:0000785"(chromatin)|go:"GO:0001664"(G protein-coupled receptor binding)|go:"GO:0001933"(negative regulation of protein phosphorylation)|go:"GO:0001934"(positive regulation of protein phosphorylation)|go:"GO:0002031"(G protein-coupled receptor internalization)|go:"GO:0002092"(positive regulation of receptor internalization)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005159"(insulin-like growth factor receptor binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005905"(clathrin-coated pit)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0006897"(endocytosis)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0007188"(adenylate cyclase-modulating G protein-coupled receptor signaling pathway)|go:"GO:0007602"(phototransduction)|go:"GO:0008277"(regulation of G protein-coupled receptor signaling pathway)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0014069"(postsynaptic density)|go:"GO:0015031"(protein transport)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0016573"(histone acetylation)|go:"GO:0016604"(nuclear body)|go:"GO:0019233"(sensory perception of pain)|go:"GO:0019899"(enzyme binding)|go:"GO:0030276"(clathrin binding)|go:"GO:0030331"(estrogen receptor binding)|go:"GO:0031143"(pseudopodium)|go:"GO:0031397"(negative regulation of protein ubiquitination)|go:"GO:0031398"(positive regulation of protein ubiquitination)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0031434"(mitogen-activated protein kinase kinase binding)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0031691"(alpha-1A adrenergic receptor binding)|go:"GO:0031692"(alpha-1B adrenergic receptor binding)|go:"GO:0031701"(angiotensin receptor binding)|go:"GO:0031762"(follicle-stimulating hormone receptor binding)|go:"GO:0031896"(V2 vasopressin receptor binding)|go:"GO:0032088"(negative regulation of NF-kappaB transcription factor activity)|go:"GO:0032092"(positive regulation of protein binding)|go:"GO:0032715"(negative regulation of interleukin-6 production)|go:"GO:0032717"(negative regulation of interleukin-8 production)|go:"GO:0033138"(positive regulation of peptidyl-serine phosphorylation)|go:"GO:0034260"(negative regulation of GTPase activity)|go:"GO:0034393"(positive regulation of smooth muscle cell apoptotic process)|go:"GO:0035025"(positive regulation of Rho protein signal transduction)|go:"GO:0035066"(positive regulation of histone acetylation)|go:"GO:0035612"(AP-2 adaptor complex binding)|go:"GO:0035615"(clathrin adaptor activity)|go:"GO:0035774"(positive regulation of insulin secretion involved in cellular response to glucose stimulus)|go:"GO:0042493"|go:"GO:0042699"(follicle-stimulating hormone signaling pathway)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0043027"(cysteine-type endopeptidase inhibitor activity involved in apoptotic process)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043149"(stress fiber assembly)|go:"GO:0043154"(negative regulation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0043197"(dendritic spine)|go:"GO:0043280"(positive regulation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0045211"(postsynaptic membrane)|go:"GO:0045309"(protein phosphorylated amino acid binding)|go:"GO:0045746"(negative regulation of Notch signaling pathway)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0050975"(sensory perception of touch)|go:"GO:0051219"(phosphoprotein binding)|go:"GO:0070373"(negative regulation of ERK1 and ERK2 cascade)|go:"GO:0070374"(positive regulation of ERK1 and ERK2 cascade)|go:"GO:0090240"(positive regulation of histone H4 acetylation)|go:"GO:1990763"(arrestin family protein binding)|interpro:IPR000698(Arrestin)|dip:DIP-40808N	-	-	-	figure legend:st1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10116(rat-brain-cortex)|taxid:10116(Rattus norvegicus brain cortex)	-	2020/10/30	2020/10/30	rogid:DtE+ZXAZKdCMvUW5K+jXQ5bH07M10116	rogid:154Z++W8VsgmEd4rSCEVkw4xLgA10116	rigid:3wclwrjZRvafcOruQOYnegkn54c	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q5XIE8	uniprotkb:P29419	intact:EBI-15348306|ensembl:ENSRNOP00000023037	intact:EBI-917140|ensembl:ENSRNOP00000000072	psi-mi:itm2b_rat(display_long)|uniprotkb:Itm2b(gene name)|psi-mi:Itm2b(display_short)|uniprotkb:Immature BRI2(gene name synonym)|uniprotkb:Transmembrane protein BRI(gene name synonym)	psi-mi:atp5i_rat(display_long)|uniprotkb:Atp5me(gene name)|psi-mi:Atp5me(display_short)|uniprotkb:ATP synthase membrane subunit e(gene name synonym)|uniprotkb:Atp5i(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Martins et al. (2018)	imex:IM-28469|pubmed:29476059	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26439741|imex:IM-28469-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSRNOG00000016271(gene)|ensembl:ENSRNOT00000023037(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001540"(amyloid-beta binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0010008"(endosome membrane)|go:"GO:0030660"(Golgi-associated vesicle membrane)|go:"GO:0031301"(integral component of organelle membrane)|go:"GO:0042985"(negative regulation of amyloid precursor protein biosynthetic process)|interpro:IPR007084(BRICHOS)|interpro:IPR040145|mint:Q5XIE8|refseq:NP_001006964.1|rgd:620727	rgd:621377|refseq:NP_536729.1|ensembl:ENSRNOG00000000064(gene)|ensembl:ENSRNOT00000000072(transcript)|go:"GO:0000276"("mitochondrial proton-transporting ATP synthase complex, coupling factor F(o)")|go:"GO:0005739"(mitochondrion)|go:"GO:0005753"(mitochondrial proton-transporting ATP synthase complex)|go:"GO:0042776"(mitochondrial ATP synthesis coupled proton transport)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0046034"(ATP metabolic process)|go:"GO:0046933"(proton-transporting ATP synthase activity, rotational mechanism)|interpro:IPR008386(ATPase, F0 complex, subunit E, mitochondrial)|mint:P29419|reactome:R-RNO-163210|reactome:R-RNO-8949613	-	-	-	figure legend:st1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10116(rat-brain-cortex)|taxid:10116(Rattus norvegicus brain cortex)	-	2020/10/30	2020/10/30	rogid:DtE+ZXAZKdCMvUW5K+jXQ5bH07M10116	rogid:vDzdXol5QxGCYvcTMmV5MTUz/QQ10116	rigid:3wclwrjZRvafcOruQOYnegkn54c	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q5XIE8	uniprotkb:Q6PST4	intact:EBI-15348306|ensembl:ENSRNOP00000023037	intact:EBI-2410213|ensembl:ENSRNOP00000041993	psi-mi:itm2b_rat(display_long)|uniprotkb:Itm2b(gene name)|psi-mi:Itm2b(display_short)|uniprotkb:Immature BRI2(gene name synonym)|uniprotkb:Transmembrane protein BRI(gene name synonym)	psi-mi:atla1_rat(display_long)|uniprotkb:Atl1(gene name)|psi-mi:Atl1(display_short)|uniprotkb:Spg3a(gene name synonym)|uniprotkb:Spastic paraplegia 3A homolog(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Martins et al. (2018)	imex:IM-28469|pubmed:29476059	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26439741|imex:IM-28469-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSRNOG00000016271(gene)|ensembl:ENSRNOT00000023037(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001540"(amyloid-beta binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0010008"(endosome membrane)|go:"GO:0030660"(Golgi-associated vesicle membrane)|go:"GO:0031301"(integral component of organelle membrane)|go:"GO:0042985"(negative regulation of amyloid precursor protein biosynthetic process)|interpro:IPR007084(BRICHOS)|interpro:IPR040145|mint:Q5XIE8|refseq:NP_001006964.1|rgd:620727	rgd:1359232|refseq:NP_001009831.1|ensembl:ENSRNOG00000005063(gene)|ensembl:ENSRNOT00000046085(transcript)|go:"GO:0000137"(Golgi cis cisterna)|go:"GO:0000139"(Golgi membrane)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0007029"(endoplasmic reticulum organization)|go:"GO:0007409"(axonogenesis)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030424"(axon)|go:"GO:0042802"(identical protein binding)|go:"GO:0051260"(protein homooligomerization)|go:"GO:0071782"(endoplasmic reticulum tubular network)|go:"GO:0098826"(endoplasmic reticulum tubular network membrane)|go:"GO:1990809"(endoplasmic reticulum tubular network membrane organization)|interpro:IPR015894(Guanylate-binding protein, N-terminal)|interpro:IPR027417|interpro:IPR030386|interpro:IPR036543|mint:Q6PST4	-	-	-	figure legend:st1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10116(rat-brain-cortex)|taxid:10116(Rattus norvegicus brain cortex)	-	2020/10/30	2020/10/30	rogid:DtE+ZXAZKdCMvUW5K+jXQ5bH07M10116	rogid:c4KiGThCEFHWueHUapbU10huLVc10116	rigid:3wclwrjZRvafcOruQOYnegkn54c	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q5XIE8	uniprotkb:Q32Q06	intact:EBI-15348306|ensembl:ENSRNOP00000023037	intact:EBI-21233983|ensembl:ENSRNOP00000019350	psi-mi:itm2b_rat(display_long)|uniprotkb:Itm2b(gene name)|psi-mi:Itm2b(display_short)|uniprotkb:Immature BRI2(gene name synonym)|uniprotkb:Transmembrane protein BRI(gene name synonym)	psi-mi:ap1m1_rat(display_long)|uniprotkb:Ap1m1(gene name)|psi-mi:Ap1m1(display_short)|uniprotkb:AP-mu chain family member mu1A(gene name synonym)|uniprotkb:Adaptor protein complex AP-1 subunit mu-1(gene name synonym)|uniprotkb:Adaptor-related protein complex 1 subunit mu-1(gene name synonym)|uniprotkb:Clathrin assembly protein complex 1 mu-1 medium chain 1(gene name synonym)|uniprotkb:Golgi adaptor HA1/AP1 adaptin mu-1 subunit(gene name synonym)|uniprotkb:Mu-adaptin 1(gene name synonym)|uniprotkb:Mu1A-adaptin(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Martins et al. (2018)	imex:IM-28469|pubmed:29476059	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26439741|imex:IM-28469-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSRNOG00000016271(gene)|ensembl:ENSRNOT00000023037(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001540"(amyloid-beta binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0010008"(endosome membrane)|go:"GO:0030660"(Golgi-associated vesicle membrane)|go:"GO:0031301"(integral component of organelle membrane)|go:"GO:0042985"(negative regulation of amyloid precursor protein biosynthetic process)|interpro:IPR007084(BRICHOS)|interpro:IPR040145|mint:Q5XIE8|refseq:NP_001006964.1|rgd:620727	ensembl:ENSRNOG00000014454(gene)|ensembl:ENSRNOT00000019350(transcript)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0016192"(vesicle-mediated transport)|go:"GO:0030131"(clathrin adaptor complex)|go:"GO:0030136"(clathrin-coated vesicle)|go:"GO:0030665"(clathrin-coated vesicle membrane)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0032438"(melanosome organization)|go:"GO:0035615"(clathrin adaptor activity)|go:"GO:0035646"(endosome to melanosome transport)|go:"GO:0043231"(intracellular membrane-bounded organelle)|interpro:IPR001392(Clathrin adaptor, mu subunit)|interpro:IPR011012(Longin-like)|interpro:IPR018240|interpro:IPR028565|interpro:IPR036168|mint:Q32Q06|reactome:R-RNO-2132295|reactome:R-RNO-432720|reactome:R-RNO-432722|reactome:R-RNO-6798695|rgd:1307653|refseq:NP_001037704.1	-	-	-	figure legend:st1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10116(rat-brain-cortex)|taxid:10116(Rattus norvegicus brain cortex)	-	2020/10/30	2020/10/30	rogid:DtE+ZXAZKdCMvUW5K+jXQ5bH07M10116	rogid:tChVvvBEw/9Le1hO4SO4UsZhypo10116	rigid:3wclwrjZRvafcOruQOYnegkn54c	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q5XIE8	uniprotkb:P0C6S7	intact:EBI-15348306|ensembl:ENSRNOP00000023037	intact:EBI-26438403	psi-mi:itm2b_rat(display_long)|uniprotkb:Itm2b(gene name)|psi-mi:Itm2b(display_short)|uniprotkb:Immature BRI2(gene name synonym)|uniprotkb:Transmembrane protein BRI(gene name synonym)	psi-mi:ans1b_rat(display_long)|uniprotkb:Anks1b(gene name)|psi-mi:Anks1b(display_short)|uniprotkb:Amyloid-beta protein intracellular domain-associated protein 1(gene name synonym)|uniprotkb:E2A-PBX1-associated protein(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Martins et al. (2018)	imex:IM-28469|pubmed:29476059	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26439741|imex:IM-28469-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSRNOG00000016271(gene)|ensembl:ENSRNOT00000023037(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001540"(amyloid-beta binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0010008"(endosome membrane)|go:"GO:0030660"(Golgi-associated vesicle membrane)|go:"GO:0031301"(integral component of organelle membrane)|go:"GO:0042985"(negative regulation of amyloid precursor protein biosynthetic process)|interpro:IPR007084(BRICHOS)|interpro:IPR040145|mint:Q5XIE8|refseq:NP_001006964.1|rgd:620727	go:"GO:0005829"(cytosol)|go:"GO:0014069"(postsynaptic density)|go:"GO:0015030"(Cajal body)|go:"GO:0043197"(dendritic spine)|go:"GO:0046875"(ephrin receptor binding)|go:"GO:0048013"(ephrin receptor signaling pathway)|go:"GO:0097120"(receptor localization to synapse)|go:"GO:0098685"(Schaffer collateral - CA1 synapse)|go:"GO:0098686"(hippocampal mossy fiber to CA3 synapse)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099092"(postsynaptic density, intracellular component)|go:"GO:0099527"(postsynapse to nucleus signaling pathway)|go:"GO:1900383"(regulation of synaptic plasticity by receptor localization to synapse)|go:"GO:0099523"(presynaptic cytosol)|mint:P0C6S7|refseq:XP_006241311.1|interpro:IPR033636|interpro:IPR002110(Ankyrin)|interpro:IPR020683|interpro:IPR036770|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR006020(Phosphotyrosine interaction region)|interpro:IPR001660(Sterile alpha motif SAM)|interpro:IPR013761(Sterile alpha motif-type)|interpro:IPR041880|interpro:IPR041882|rgd:1565556	-	-	-	figure legend:st1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10116(rat-brain-cortex)|taxid:10116(Rattus norvegicus brain cortex)	-	2020/10/30	2020/10/30	rogid:DtE+ZXAZKdCMvUW5K+jXQ5bH07M10116	rogid:ZxrnxpC8K4UWTMjr3aKwguZq2qY10116	rigid:3wclwrjZRvafcOruQOYnegkn54c	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q5XIE8	uniprotkb:Q9Z1P2	intact:EBI-15348306|ensembl:ENSRNOP00000023037	intact:EBI-920286|ensembl:ENSRNOP00000069598	psi-mi:itm2b_rat(display_long)|uniprotkb:Itm2b(gene name)|psi-mi:Itm2b(display_short)|uniprotkb:Immature BRI2(gene name synonym)|uniprotkb:Transmembrane protein BRI(gene name synonym)	psi-mi:actn1_rat(display_long)|uniprotkb:Actn1(gene name)|psi-mi:Actn1(display_short)|uniprotkb:Alpha-actinin cytoskeletal isoform(gene name synonym)|uniprotkb:Non-muscle alpha-actinin-1(gene name synonym)|uniprotkb:F-actin cross-linking protein(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Martins et al. (2018)	imex:IM-28469|pubmed:29476059	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26439741|imex:IM-28469-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSRNOG00000016271(gene)|ensembl:ENSRNOT00000023037(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001540"(amyloid-beta binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0010008"(endosome membrane)|go:"GO:0030660"(Golgi-associated vesicle membrane)|go:"GO:0031301"(integral component of organelle membrane)|go:"GO:0042985"(negative regulation of amyloid precursor protein biosynthetic process)|interpro:IPR007084(BRICHOS)|interpro:IPR040145|mint:Q5XIE8|refseq:NP_001006964.1|rgd:620727	rgd:70907|refseq:NP_112267.1|ensembl:ENSRNOG00000056756(gene)|ensembl:ENSRNOT00000088795(transcript)|go:"GO:0001725"(stress fiber)|go:"GO:0001726"(ruffle)|go:"GO:0003725"(double-stranded RNA binding)|go:"GO:0005178"(integrin binding)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005519"(cytoskeletal regulatory protein binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005886"(plasma membrane)|go:"GO:0005903"(brush border)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005916"(fascia adherens)|go:"GO:0005925"(focal adhesion)|go:"GO:0007015"(actin filament organization)|go:"GO:0017166"(vinculin binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030017"(sarcomere)|go:"GO:0030018"(Z disc)|go:"GO:0030054"(cell junction)|go:"GO:0030220"(platelet formation)|go:"GO:0030374"(nuclear receptor coactivator activity)|go:"GO:0036344"(platelet morphogenesis)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0042995"(cell projection)|go:"GO:0043197"(dendritic spine)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0048041"(focal adhesion assembly)|go:"GO:0051015"(actin filament binding)|go:"GO:0051017"(actin filament bundle assembly)|go:"GO:0051271"(negative regulation of cellular component movement)|go:"GO:0051639"(actin filament network formation)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099186"(structural constituent of postsynapse)|interpro:IPR001589(Actinin-type, actin-binding, conserved site)|interpro:IPR001715(Calponin-like actin-binding)|interpro:IPR002017(Spectrin repeat)|interpro:IPR002048(Calcium-binding EF-hand)|interpro:IPR011992(EF-Hand type)|interpro:IPR014837(EF-hand, Ca insensitive)|interpro:IPR018159|interpro:IPR018247|interpro:IPR036872|mint:Q9Z1P2|reactome:R-RNO-114608|reactome:R-RNO-446388|reactome:R-RNO-9013405|reactome:R-RNO-9013418|reactome:R-RNO-9035034	-	-	-	figure legend:st1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10116(rat-brain-cortex)|taxid:10116(Rattus norvegicus brain cortex)	-	2020/10/30	2020/10/30	rogid:DtE+ZXAZKdCMvUW5K+jXQ5bH07M10116	rogid:e8zdF7HOx12sx9WE9oJe6tk9br810116	rigid:3wclwrjZRvafcOruQOYnegkn54c	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q5XIE8	uniprotkb:P68035	intact:EBI-15348306|ensembl:ENSRNOP00000023037	intact:EBI-26438357|ensembl:ENSRNOP00000011773|uniprotkb:A0JPJ4|uniprotkb:P04270	psi-mi:itm2b_rat(display_long)|uniprotkb:Itm2b(gene name)|psi-mi:Itm2b(display_short)|uniprotkb:Immature BRI2(gene name synonym)|uniprotkb:Transmembrane protein BRI(gene name synonym)	psi-mi:actc_rat(display_long)|uniprotkb:Actc1(gene name)|psi-mi:Actc1(display_short)|uniprotkb:Actc(gene name synonym)|uniprotkb:Alpha-cardiac actin(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Martins et al. (2018)	imex:IM-28469|pubmed:29476059	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26439741|imex:IM-28469-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSRNOG00000016271(gene)|ensembl:ENSRNOT00000023037(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001540"(amyloid-beta binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0010008"(endosome membrane)|go:"GO:0030660"(Golgi-associated vesicle membrane)|go:"GO:0031301"(integral component of organelle membrane)|go:"GO:0042985"(negative regulation of amyloid precursor protein biosynthetic process)|interpro:IPR007084(BRICHOS)|interpro:IPR040145|mint:Q5XIE8|refseq:NP_001006964.1|rgd:620727	go:"GO:0000146"(microfilament motor activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005869"(dynactin complex)|go:"GO:0005884"(actin filament)|go:"GO:0007015"(actin filament organization)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0017022"(myosin binding)|go:"GO:0030017"(sarcomere)|go:"GO:0030027"(lamellipodium)|go:"GO:0030048"(actin filament-based movement)|go:"GO:0030175"(filopodium)|go:"GO:0030240"(skeletal muscle thin filament assembly)|go:"GO:0031032"(actomyosin structure organization)|go:"GO:0031674"(I band)|go:"GO:0033275"(actin-myosin filament sliding)|go:"GO:0042493"|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0044297"(cell body)|go:"GO:0045202"(synapse)|go:"GO:0045471"(response to ethanol)|go:"GO:0055003"(cardiac myofibril assembly)|go:"GO:0055008"(cardiac muscle tissue morphogenesis)|go:"GO:0060047"(heart contraction)|go:"GO:0060048"(cardiac muscle contraction)|go:"GO:0070252"(actin-mediated cell contraction)|ensembl:ENSRNOT00000011773(transcript)|go:"GO:0090131"(mesenchyme migration)|go:"GO:0098978"(glutamatergic synapse)|interpro:IPR004000(Actin/actin-like)|interpro:IPR004001(Actin, conserved site)|interpro:IPR020902|interpro:IPR043129|mint:P68035|reactome:R-RNO-390522|reactome:R-RNO-8980692|reactome:R-RNO-9013026|ensembl:ENSRNOG00000008536(gene)|refseq:NP_062056.1|rgd:2026	-	-	-	figure legend:st1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10116(rat-brain-cortex)|taxid:10116(Rattus norvegicus brain cortex)	-	2020/10/30	2020/10/30	rogid:DtE+ZXAZKdCMvUW5K+jXQ5bH07M10116	rogid:U/lKYqWUWMSC3fBHFaAcgzfk+3w10116	rigid:3wclwrjZRvafcOruQOYnegkn54c	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q5XIE8	uniprotkb:P47198	intact:EBI-15348306|ensembl:ENSRNOP00000023037	intact:EBI-931434	psi-mi:itm2b_rat(display_long)|uniprotkb:Itm2b(gene name)|psi-mi:Itm2b(display_short)|uniprotkb:Immature BRI2(gene name synonym)|uniprotkb:Transmembrane protein BRI(gene name synonym)	psi-mi:rl22_rat(display_long)|uniprotkb:Rpl22(gene name)|psi-mi:Rpl22(display_short)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Martins et al. (2018)	imex:IM-28469|pubmed:29476059	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26439741|imex:IM-28469-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSRNOG00000016271(gene)|ensembl:ENSRNOT00000023037(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001540"(amyloid-beta binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0010008"(endosome membrane)|go:"GO:0030660"(Golgi-associated vesicle membrane)|go:"GO:0031301"(integral component of organelle membrane)|go:"GO:0042985"(negative regulation of amyloid precursor protein biosynthetic process)|interpro:IPR007084(BRICHOS)|interpro:IPR040145|mint:Q5XIE8|refseq:NP_001006964.1|rgd:620727	rgd:621189|refseq:NP_112366.1|interpro:IPR002671(Ribosomal protein L22e)|mint:P47198|interpro:IPR038526|go:"GO:0002181"(cytoplasmic translation)|go:"GO:0003723"(RNA binding)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005840"(ribosome)|go:"GO:0008201"(heparin binding)|go:"GO:0022625"(cytosolic large ribosomal subunit)|go:"GO:0022626"(cytosolic ribosome)|go:"GO:0042802"(identical protein binding)|go:"GO:0045182"(translation regulator activity)|go:"GO:0046632"(alpha-beta T cell differentiation)|go:"GO:0098793"(presynapse)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099577"(regulation of translation at presynapse, modulating synaptic transmission)|go:"GO:1990904"(ribonucleoprotein complex)|reactome:R-RNO-156827|reactome:R-RNO-1799339|reactome:R-RNO-6791226|reactome:R-RNO-72689|reactome:R-RNO-72706|reactome:R-RNO-975956|reactome:R-RNO-975957	-	-	-	figure legend:st1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10116(rat-brain-cortex)|taxid:10116(Rattus norvegicus brain cortex)	-	2020/10/30	2020/10/30	rogid:DtE+ZXAZKdCMvUW5K+jXQ5bH07M10116	rogid:XizbNAqzHo9UA8CTtALhxmMzqoc10116	rigid:3wclwrjZRvafcOruQOYnegkn54c	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q5XIE8	uniprotkb:P62282	intact:EBI-15348306|ensembl:ENSRNOP00000023037	intact:EBI-352498|uniprotkb:P04643|ensembl:ENSRNOP00000061250	psi-mi:itm2b_rat(display_long)|uniprotkb:Itm2b(gene name)|psi-mi:Itm2b(display_short)|uniprotkb:Immature BRI2(gene name synonym)|uniprotkb:Transmembrane protein BRI(gene name synonym)	psi-mi:rs11_rat(display_long)|uniprotkb:Rps11(gene name)|psi-mi:Rps11(display_short)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Martins et al. (2018)	imex:IM-28469|pubmed:29476059	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26439741|imex:IM-28469-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSRNOG00000016271(gene)|ensembl:ENSRNOT00000023037(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001540"(amyloid-beta binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0010008"(endosome membrane)|go:"GO:0030660"(Golgi-associated vesicle membrane)|go:"GO:0031301"(integral component of organelle membrane)|go:"GO:0042985"(negative regulation of amyloid precursor protein biosynthetic process)|interpro:IPR007084(BRICHOS)|interpro:IPR040145|mint:Q5XIE8|refseq:NP_001006964.1|rgd:620727	rgd:621026|refseq:NP_112372.1|ensembl:ENSRNOG00000020595(gene)|ensembl:ENSRNOT00000066328(transcript)|go:"GO:0001649"(osteoblast differentiation)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0006412"(translation)|go:"GO:0016020"(membrane)|go:"GO:0019843"(rRNA binding)|go:"GO:0022626"(cytosolic ribosome)|go:"GO:0022627"(cytosolic small ribosomal subunit)|interpro:IPR000266(Ribosomal protein S17)|interpro:IPR012340(Nucleic acid-binding, OB-fold)|interpro:IPR019979|interpro:IPR028333|interpro:IPR032440|mint:P62282|reactome:R-RNO-156827|reactome:R-RNO-1799339|reactome:R-RNO-6791226|reactome:R-RNO-72649|reactome:R-RNO-72689|reactome:R-RNO-72695|reactome:R-RNO-72702|reactome:R-RNO-72706|reactome:R-RNO-975956|reactome:R-RNO-975957	-	-	-	figure legend:st1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10116(rat-brain-cortex)|taxid:10116(Rattus norvegicus brain cortex)	-	2020/10/30	2020/10/30	rogid:DtE+ZXAZKdCMvUW5K+jXQ5bH07M10116	rogid:0fqJjtWAuz31VTKt2mbteRoi8vA10116	rigid:3wclwrjZRvafcOruQOYnegkn54c	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q5XIE8	uniprotkb:P11960	intact:EBI-15348306|ensembl:ENSRNOP00000023037	intact:EBI-916408	psi-mi:itm2b_rat(display_long)|uniprotkb:Itm2b(gene name)|psi-mi:Itm2b(display_short)|uniprotkb:Immature BRI2(gene name synonym)|uniprotkb:Transmembrane protein BRI(gene name synonym)	psi-mi:odba_rat(display_long)|uniprotkb:Branched-chain alpha-keto acid dehydrogenase E1 component alpha chain(gene name synonym)|uniprotkb:Bckdha(gene name)|psi-mi:Bckdha(display_short)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Martins et al. (2018)	imex:IM-28469|pubmed:29476059	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26439741|imex:IM-28469-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSRNOG00000016271(gene)|ensembl:ENSRNOT00000023037(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001540"(amyloid-beta binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0010008"(endosome membrane)|go:"GO:0030660"(Golgi-associated vesicle membrane)|go:"GO:0031301"(integral component of organelle membrane)|go:"GO:0042985"(negative regulation of amyloid precursor protein biosynthetic process)|interpro:IPR007084(BRICHOS)|interpro:IPR040145|mint:Q5XIE8|refseq:NP_001006964.1|rgd:620727	interpro:IPR034616|go:"GO:0009083"(branched-chain amino acid catabolic process)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0046872"(metal ion binding)|go:"GO:0047101"("2-oxoisovalerate dehydrogenase (acylating) activity")|go:"GO:0051384"(response to glucocorticoid)|go:"GO:0003863"("3-methyl-2-oxobutanoate dehydrogenase (2-methylpropanoyl-transferring) activity")|go:"GO:0005739"(mitochondrion)|go:"GO:0005947"(mitochondrial alpha-ketoglutarate dehydrogenase complex)|go:"GO:0007584"(response to nutrient)|go:"GO:0051591"(response to cAMP)|reactome:R-RNO-389661|reactome:R-RNO-70895|mint:P11960|rgd:2196|refseq:NP_036914.1|interpro:IPR001017(Dehydrogenase, E1 component)|interpro:IPR029061	-	-	-	figure legend:st1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10116(rat-brain-cortex)|taxid:10116(Rattus norvegicus brain cortex)	-	2020/10/30	2020/10/30	rogid:DtE+ZXAZKdCMvUW5K+jXQ5bH07M10116	rogid:XAi/0rSMFYOnlY8SZrOBbpSsI9Q10116	rigid:3wclwrjZRvafcOruQOYnegkn54c	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q5XIE8	uniprotkb:P68255	intact:EBI-15348306|ensembl:ENSRNOP00000023037	intact:EBI-400680|uniprotkb:P35216|ensembl:ENSRNOP00000072011	psi-mi:itm2b_rat(display_long)|uniprotkb:Itm2b(gene name)|psi-mi:Itm2b(display_short)|uniprotkb:Immature BRI2(gene name synonym)|uniprotkb:Transmembrane protein BRI(gene name synonym)	psi-mi:1433t_rat(display_long)|uniprotkb:Ywhaq(gene name)|psi-mi:Ywhaq(display_short)|uniprotkb:14-3-3 protein tau(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Martins et al. (2018)	imex:IM-28469|pubmed:29476059	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26439741|imex:IM-28469-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSRNOG00000016271(gene)|ensembl:ENSRNOT00000023037(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001540"(amyloid-beta binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0010008"(endosome membrane)|go:"GO:0030660"(Golgi-associated vesicle membrane)|go:"GO:0031301"(integral component of organelle membrane)|go:"GO:0042985"(negative regulation of amyloid precursor protein biosynthetic process)|interpro:IPR007084(BRICHOS)|interpro:IPR040145|mint:Q5XIE8|refseq:NP_001006964.1|rgd:620727	rgd:3979|refseq:NP_037185.1|ensembl:ENSRNOG00000051650(gene)|ensembl:ENSRNOT00000077786(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0006605"(protein targeting)|go:"GO:0007264"(small GTPase mediated signal transduction)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034766"(negative regulation of ion transmembrane transport)|go:"GO:0042802"(identical protein binding)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0045202"(synapse)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0047485"(protein N-terminus binding)|go:"GO:0071889"(14-3-3 protein binding)|interpro:IPR000308(14-3-3 protein)|interpro:IPR023409|interpro:IPR023410|interpro:IPR036815|interpro:IPR042584|mint:P68255|reactome:R-RNO-111447|reactome:R-RNO-5625740|reactome:R-RNO-5628897|reactome:R-RNO-75035|reactome:R-RNO-9614399|dip:DIP-947N	-	-	-	figure legend:st1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10116(rat-brain-cortex)|taxid:10116(Rattus norvegicus brain cortex)	-	2020/10/30	2020/10/30	rogid:DtE+ZXAZKdCMvUW5K+jXQ5bH07M10116	rogid:l8bki6QJJEH5S5NIwQdm/MAYcc010116	rigid:3wclwrjZRvafcOruQOYnegkn54c	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q5XIE8	uniprotkb:P13233	intact:EBI-15348306|ensembl:ENSRNOP00000023037	intact:EBI-2640672|uniprotkb:Q4V796|uniprotkb:Q64575|ensembl:ENSRNOP00000023875	psi-mi:itm2b_rat(display_long)|uniprotkb:Itm2b(gene name)|psi-mi:Itm2b(display_short)|uniprotkb:Immature BRI2(gene name synonym)|uniprotkb:Transmembrane protein BRI(gene name synonym)	psi-mi:cn37_rat(display_long)|uniprotkb:Cnp(gene name)|psi-mi:Cnp(display_short)|uniprotkb:Cnp1(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Martins et al. (2018)	imex:IM-28469|pubmed:29476059	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26439741|imex:IM-28469-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSRNOG00000016271(gene)|ensembl:ENSRNOT00000023037(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001540"(amyloid-beta binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0010008"(endosome membrane)|go:"GO:0030660"(Golgi-associated vesicle membrane)|go:"GO:0031301"(integral component of organelle membrane)|go:"GO:0042985"(negative regulation of amyloid precursor protein biosynthetic process)|interpro:IPR007084(BRICHOS)|interpro:IPR040145|mint:Q5XIE8|refseq:NP_001006964.1|rgd:620727	rgd:2368|refseq:NP_036941.1|ensembl:ENSRNOG00000017496(gene)|ensembl:ENSRNOT00000023872(transcript)|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0003723"(RNA binding)|go:"GO:0004113"(2',3'-cyclic-nucleotide 3'-phosphodiesterase activity)|go:"GO:0005615"(extracellular space)|go:"GO:0005737"(cytoplasm)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005886"(plasma membrane)|go:"GO:0005902"(microvillus)|go:"GO:0007409"(axonogenesis)|go:"GO:0007568"(aging)|go:"GO:0008344"(adult locomotory behavior)|go:"GO:0009214"(cyclic nucleotide catabolic process)|go:"GO:0009636"(response to toxic substance)|go:"GO:0016020"(membrane)|go:"GO:0030551"(cyclic nucleotide binding)|go:"GO:0030900"(forebrain development)|go:"GO:0031143"(pseudopodium)|go:"GO:0032496"(response to lipopolysaccharide)|go:"GO:0035748"(myelin sheath abaxonal region)|go:"GO:0035749"(myelin sheath adaxonal region)|go:"GO:0042470"(melanosome)|go:"GO:0042995"(cell projection)|go:"GO:0043209"(myelin sheath)|go:"GO:0046902"(regulation of mitochondrial membrane permeability)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0048709"(oligodendrocyte differentiation)|interpro:IPR008431(Cyclic nucleotide phosphodiesterase)|interpro:IPR009097(RNA ligase/cyclic nucleotide phosphodiesterase)|interpro:IPR027417|mint:P13233|rcsb pdb:2ILX	-	-	-	figure legend:st1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10116(rat-brain-cortex)|taxid:10116(Rattus norvegicus brain cortex)	-	2020/10/30	2020/10/30	rogid:DtE+ZXAZKdCMvUW5K+jXQ5bH07M10116	rogid:+0AAow8yyo0d6aKTghtTmcS2SZw10116	rigid:3wclwrjZRvafcOruQOYnegkn54c	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q5XIE8	uniprotkb:P08413	intact:EBI-15348306|ensembl:ENSRNOP00000023037	intact:EBI-916155	psi-mi:itm2b_rat(display_long)|uniprotkb:Itm2b(gene name)|psi-mi:Itm2b(display_short)|uniprotkb:Immature BRI2(gene name synonym)|uniprotkb:Transmembrane protein BRI(gene name synonym)	psi-mi:kcc2b_rat(display_long)|uniprotkb:Camk2b(gene name)|psi-mi:Camk2b(display_short)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Martins et al. (2018)	imex:IM-28469|pubmed:29476059	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26439741|imex:IM-28469-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSRNOG00000016271(gene)|ensembl:ENSRNOT00000023037(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001540"(amyloid-beta binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0010008"(endosome membrane)|go:"GO:0030660"(Golgi-associated vesicle membrane)|go:"GO:0031301"(integral component of organelle membrane)|go:"GO:0042985"(negative regulation of amyloid precursor protein biosynthetic process)|interpro:IPR007084(BRICHOS)|interpro:IPR040145|mint:Q5XIE8|refseq:NP_001006964.1|rgd:620727	rgd:2262|refseq:NP_001035815.1|refseq:NP_068507.2|go:"GO:0000082"(G1/S transition of mitotic cell cycle)|go:"GO:0002030"(inhibitory G protein-coupled receptor phosphorylation)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0004683"(calmodulin-dependent protein kinase activity)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005815"(microtubule organizing center)|go:"GO:0005829"(cytosol)|go:"GO:0005954"(calcium- and calmodulin-dependent protein kinase complex)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:0110088"(hippocampal neuron apoptotic process)|go:"GO:0006816"(calcium ion transport)|go:"GO:0010976"(positive regulation of neuron projection development)|go:"GO:0014069"(postsynaptic density)|go:"GO:0018105"(peptidyl-serine phosphorylation)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030425"(dendrite)|go:"GO:0032222"(regulation of synaptic transmission, cholinergic)|go:"GO:0032430"(positive regulation of phospholipase A2 activity)|go:"GO:0033017"(sarcoplasmic reticulum membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043005"(neuron projection)|go:"GO:0043204"(perikaryon)|go:"GO:0043274"(phospholipase binding)|go:"GO:0046686"(response to cadmium ion)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0048169"(regulation of long-term neuronal synaptic plasticity)|go:"GO:0048858"(cell projection morphogenesis)|go:"GO:0050885"(neuromuscular process controlling balance)|go:"GO:0051233"(spindle midzone)|go:"GO:0060291"(long-term synaptic potentiation)|go:"GO:0060466"(activation of meiosis involved in egg activation)|go:"GO:0061003"(positive regulation of dendritic spine morphogenesis)|go:"GO:0090129"(positive regulation of synapse maturation)|go:"GO:0098973"(structural constituent of postsynaptic actin cytoskeleton)|reactome:R-RNO-5578775|reactome:R-RNO-5673000|reactome:R-RNO-5673001|reactome:R-RNO-877300|reactome:R-RNO-936837|mint:P08413|go:"GO:1903076"(regulation of protein localization to plasma membrane)|go:"GO:1905375"(cellular response to homocysteine)|go:"GO:1990911"(response to psychosocial stress)|go:"GO:2001222"(regulation of neuron migration)|go:"GO:2001235"(positive regulation of apoptotic signaling pathway)|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR013543(Calcium/calmodulin dependent protein kinase II, association-domain)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR032710|rcsb pdb:6HCS|reactome:R-RNO-3371571|reactome:R-RNO-399719|reactome:R-RNO-438066|reactome:R-RNO-5576892|dip:DIP-36948N	-	-	-	figure legend:st1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10116(rat-brain-cortex)|taxid:10116(Rattus norvegicus brain cortex)	-	2020/10/30	2020/10/30	rogid:DtE+ZXAZKdCMvUW5K+jXQ5bH07M10116	rogid:RojSx9Ro3RlYG4LM8c8FroRaKzs10116	rigid:3wclwrjZRvafcOruQOYnegkn54c	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q5XIE8	uniprotkb:P11275	intact:EBI-15348306|ensembl:ENSRNOP00000023037	intact:EBI-2640645	psi-mi:itm2b_rat(display_long)|uniprotkb:Itm2b(gene name)|psi-mi:Itm2b(display_short)|uniprotkb:Immature BRI2(gene name synonym)|uniprotkb:Transmembrane protein BRI(gene name synonym)	psi-mi:kcc2a_rat(display_long)|uniprotkb:Camk2a(gene name)|psi-mi:Camk2a(display_short)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Martins et al. (2018)	imex:IM-28469|pubmed:29476059	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26439741|imex:IM-28469-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSRNOG00000016271(gene)|ensembl:ENSRNOT00000023037(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001540"(amyloid-beta binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0010008"(endosome membrane)|go:"GO:0030660"(Golgi-associated vesicle membrane)|go:"GO:0031301"(integral component of organelle membrane)|go:"GO:0042985"(negative regulation of amyloid precursor protein biosynthetic process)|interpro:IPR007084(BRICHOS)|interpro:IPR040145|mint:Q5XIE8|refseq:NP_001006964.1|rgd:620727	rgd:2261|refseq:NP_037052.1|go:"GO:0000082"(G1/S transition of mitotic cell cycle)|go:"GO:0002931"(response to ischemia)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0004683"(calmodulin-dependent protein kinase activity)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005954"(calcium- and calmodulin-dependent protein kinase complex)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0006816"(calcium ion transport)|go:"GO:0009931"(calcium-dependent protein serine/threonine kinase activity)|go:"GO:0010666"(positive regulation of cardiac muscle cell apoptotic process)|go:"GO:0014069"(postsynaptic density)|go:"GO:0016020"(membrane)|go:"GO:0016301"(kinase activity)|go:"GO:0018105"(peptidyl-serine phosphorylation)|go:"GO:0030424"(axon)|go:"GO:0005829"(cytosol)|go:"GO:0030425"(dendrite)|go:"GO:0032794"(GTPase activating protein binding)|go:"GO:0032839"(dendrite cytoplasm)|go:"GO:0035235"(ionotropic glutamate receptor signaling pathway)|go:"GO:0035254"(glutamate receptor binding)|go:"GO:0038166"(angiotensin-activated signaling pathway)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043005"(neuron projection)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043197"(dendritic spine)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0046872"(metal ion binding)|go:"GO:0046928"(regulation of neurotransmitter secretion)|go:"GO:0048168"(regulation of neuronal synaptic plasticity)|go:"GO:0048813"(dendrite morphogenesis)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|go:"GO:0051346"(negative regulation of hydrolase activity)|go:"GO:0051928"(positive regulation of calcium ion transport)|go:"GO:0060996"(dendritic spine development)|go:"GO:0098685"(Schaffer collateral - CA1 synapse)|go:"GO:0098696"(regulation of neurotransmitter receptor localization to postsynaptic specialization membrane)|go:"GO:0098970"(postsynaptic neurotransmitter receptor diffusion trapping)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0098989"(NMDA selective glutamate receptor signaling pathway)|go:"GO:0099004"(calmodulin dependent kinase signaling pathway)|go:"GO:0099148"(regulation of synaptic vesicle docking)|go:"GO:0099523"(presynaptic cytosol)|go:"GO:0099524"(postsynaptic cytosol)|go:"GO:0099573"(glutamatergic postsynaptic density)|go:"GO:0099634"(postsynaptic specialization membrane)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:1902108"(regulation of mitochondrial membrane permeability involved in apoptotic process)|go:"GO:1903076"(regulation of protein localization to plasma membrane)|go:"GO:1990443"(peptidyl-threonine autophosphorylation)|go:"GO:2000124"(regulation of endocannabinoid signaling pathway)|go:"GO:2001222"(regulation of neuron migration)|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR013543(Calcium/calmodulin dependent protein kinase II, association-domain)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR032710|rcsb pdb:1CDM|rcsb pdb:1CM1|rcsb pdb:1CM4|rcsb pdb:5U6Y|reactome:R-RNO-3371571|reactome:R-RNO-399719|reactome:R-RNO-4086398|reactome:R-RNO-438066|reactome:R-RNO-5576892|reactome:R-RNO-5578775|reactome:R-RNO-5673000|reactome:R-RNO-5673001|reactome:R-RNO-877300|reactome:R-RNO-936837|dip:DIP-29639N|mint:P11275	-	-	-	figure legend:st1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10116(rat-brain-cortex)|taxid:10116(Rattus norvegicus brain cortex)	-	2020/10/30	2020/10/30	rogid:DtE+ZXAZKdCMvUW5K+jXQ5bH07M10116	rogid:mHdSlhGhe3sMOyO+YGwROtGOGfY10116	rigid:3wclwrjZRvafcOruQOYnegkn54c	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q5XIE8	uniprotkb:Q5FVI4	intact:EBI-15348306|ensembl:ENSRNOP00000023037	intact:EBI-26439720|ensembl:ENSRNOP00000024867|ensembl:ENSRNOP00000066509	psi-mi:itm2b_rat(display_long)|uniprotkb:Itm2b(gene name)|psi-mi:Itm2b(display_short)|uniprotkb:Immature BRI2(gene name synonym)|uniprotkb:Transmembrane protein BRI(gene name synonym)	psi-mi:cend_rat(display_long)|uniprotkb:Cend1(gene name)|psi-mi:Cend1(display_short)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Martins et al. (2018)	imex:IM-28469|pubmed:29476059	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26439741|imex:IM-28469-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSRNOG00000016271(gene)|ensembl:ENSRNOT00000023037(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001540"(amyloid-beta binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0010008"(endosome membrane)|go:"GO:0030660"(Golgi-associated vesicle membrane)|go:"GO:0031301"(integral component of organelle membrane)|go:"GO:0042985"(negative regulation of amyloid precursor protein biosynthetic process)|interpro:IPR007084(BRICHOS)|interpro:IPR040145|mint:Q5XIE8|refseq:NP_001006964.1|rgd:620727	ensembl:ENSRNOG00000018448(gene)|ensembl:ENSRNOG00000045680(gene)|ensembl:ENSRNOT00000024867(transcript)|ensembl:ENSRNOT00000074016(transcript)|go:"GO:0007628"(adult walking behavior)|go:"GO:0016021"(integral component of membrane)|go:"GO:0021686"(cerebellar granular layer maturation)|go:"GO:0021702"(cerebellar Purkinje cell differentiation)|go:"GO:0021933"(radial glia guided migration of cerebellar granule cell)|go:"GO:0021941"(negative regulation of cerebellar granule cell precursor proliferation)|go:"GO:0030182"(neuron differentiation)|interpro:IPR020162|mint:Q5FVI4|refseq:NP_001014185.1|refseq:XP_003749055.1|refseq:XP_008772956.1|rgd:1309401	-	-	-	figure legend:st1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10116(rat-brain-cortex)|taxid:10116(Rattus norvegicus brain cortex)	-	2020/10/30	2020/10/30	rogid:DtE+ZXAZKdCMvUW5K+jXQ5bH07M10116	rogid:J40Tb1hzqxbyIVe+3MXRCNvbNOo10116	rigid:3wclwrjZRvafcOruQOYnegkn54c	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q5XIE8	uniprotkb:Q66HR5	intact:EBI-15348306|ensembl:ENSRNOP00000023037	intact:EBI-26437895|ensembl:ENSRNOP00000021522|ensembl:ENSRNOP00000064554|uniprotkb:Q8R443	psi-mi:itm2b_rat(display_long)|uniprotkb:Itm2b(gene name)|psi-mi:Itm2b(display_short)|uniprotkb:Immature BRI2(gene name synonym)|uniprotkb:Transmembrane protein BRI(gene name synonym)	psi-mi:caco1_rat(display_long)|uniprotkb:Calcoco1(gene name)|psi-mi:Calcoco1(display_short)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Martins et al. (2018)	imex:IM-28469|pubmed:29476059	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26439741|imex:IM-28469-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSRNOG00000016271(gene)|ensembl:ENSRNOT00000023037(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001540"(amyloid-beta binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0010008"(endosome membrane)|go:"GO:0030660"(Golgi-associated vesicle membrane)|go:"GO:0031301"(integral component of organelle membrane)|go:"GO:0042985"(negative regulation of amyloid precursor protein biosynthetic process)|interpro:IPR007084(BRICHOS)|interpro:IPR040145|mint:Q5XIE8|refseq:NP_001006964.1|rgd:620727	ensembl:ENSRNOG00000015447(gene)|ensembl:ENSRNOG00000048982(gene)|ensembl:ENSRNOT00000021523(transcript)|ensembl:ENSRNOT00000070855(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0007165"(signal transduction)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0030374"(nuclear receptor coactivator activity)|go:"GO:0030518"(intracellular steroid hormone receptor signaling pathway)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|go:"GO:0070016"(armadillo repeat domain binding)|interpro:IPR012852(Coiled-coil transcriptional coactivator-like)|interpro:IPR041611|interpro:IPR041641|mint:Q66HR5|go:"GO:0016055"(Wnt signaling pathway)|refseq:NP_631929.1|refseq:XP_003750466.1|refseq:XP_017459014.1|rgd:619812	-	-	-	figure legend:st1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10116(rat-brain-cortex)|taxid:10116(Rattus norvegicus brain cortex)	-	2020/10/30	2020/10/30	rogid:DtE+ZXAZKdCMvUW5K+jXQ5bH07M10116	rogid:LlzzRDYh96ak+uCTha2DsL0T8BM10116	rigid:3wclwrjZRvafcOruQOYnegkn54c	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q5XIE8	uniprotkb:P11730	intact:EBI-15348306|ensembl:ENSRNOP00000023037	intact:EBI-916359|uniprotkb:Q64003|uniprotkb:Q64004|ensembl:ENSRNOP00000062321	psi-mi:itm2b_rat(display_long)|uniprotkb:Itm2b(gene name)|psi-mi:Itm2b(display_short)|uniprotkb:Immature BRI2(gene name synonym)|uniprotkb:Transmembrane protein BRI(gene name synonym)	psi-mi:kcc2g_rat(display_long)|uniprotkb:Camk2g(gene name)|psi-mi:Camk2g(display_short)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Martins et al. (2018)	imex:IM-28469|pubmed:29476059	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26439741|imex:IM-28469-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSRNOG00000016271(gene)|ensembl:ENSRNOT00000023037(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001540"(amyloid-beta binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0010008"(endosome membrane)|go:"GO:0030660"(Golgi-associated vesicle membrane)|go:"GO:0031301"(integral component of organelle membrane)|go:"GO:0042985"(negative regulation of amyloid precursor protein biosynthetic process)|interpro:IPR007084(BRICHOS)|interpro:IPR040145|mint:Q5XIE8|refseq:NP_001006964.1|rgd:620727	rgd:621802|refseq:NP_598289.1|ensembl:ENSRNOG00000009783(gene)|ensembl:ENSRNOT00000066163(transcript)|go:"GO:0000082"(G1/S transition of mitotic cell cycle)|go:"GO:0001666"(response to hypoxia)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0004683"(calmodulin-dependent protein kinase activity)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005954"(calcium- and calmodulin-dependent protein kinase complex)|go:"GO:0006816"(calcium ion transport)|go:"GO:0006979"(response to oxidative stress)|go:"GO:0007399"(nervous system development)|go:"GO:0010975"(regulation of neuron projection development)|go:"GO:0014069"(postsynaptic density)|go:"GO:0030154"(cell differentiation)|go:"GO:0033017"(sarcoplasmic reticulum membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043005"(neuron projection)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0048169"(regulation of long-term neuronal synaptic plasticity)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:1901897"(regulation of relaxation of cardiac muscle)|go:"GO:1903076"(regulation of protein localization to plasma membrane)|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR013543(Calcium/calmodulin dependent protein kinase II, association-domain)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR032710|mint:P11730|reactome:R-RNO-3371571|reactome:R-RNO-399719|reactome:R-RNO-438066|reactome:R-RNO-5576892|reactome:R-RNO-5578775|reactome:R-RNO-5673000|reactome:R-RNO-5673001|reactome:R-RNO-877300|reactome:R-RNO-936837|refseq:XP_008768721.1	-	-	-	figure legend:st1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10116(rat-brain-cortex)|taxid:10116(Rattus norvegicus brain cortex)	-	2020/10/30	2020/10/30	rogid:DtE+ZXAZKdCMvUW5K+jXQ5bH07M10116	rogid:HFnqkrMFXXpL90nLx86YWIJ8z/810116	rigid:3wclwrjZRvafcOruQOYnegkn54c	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q5XIE8	uniprotkb:P15791	intact:EBI-15348306|ensembl:ENSRNOP00000023037	intact:EBI-916602|uniprotkb:P97915|uniprotkb:P97916|uniprotkb:Q3B7L0|uniprotkb:Q63904|uniprotkb:Q63905|uniprotkb:Q63906|uniprotkb:Q63907|uniprotkb:Q63908|ensembl:ENSRNOP00000016026|ensembl:ENSRNOP00000062625	psi-mi:itm2b_rat(display_long)|uniprotkb:Itm2b(gene name)|psi-mi:Itm2b(display_short)|uniprotkb:Immature BRI2(gene name synonym)|uniprotkb:Transmembrane protein BRI(gene name synonym)	psi-mi:kcc2d_rat(display_long)|uniprotkb:Camk2d(gene name)|psi-mi:Camk2d(display_short)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Martins et al. (2018)	imex:IM-28469|pubmed:29476059	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26439741|imex:IM-28469-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSRNOG00000016271(gene)|ensembl:ENSRNOT00000023037(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001540"(amyloid-beta binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0010008"(endosome membrane)|go:"GO:0030660"(Golgi-associated vesicle membrane)|go:"GO:0031301"(integral component of organelle membrane)|go:"GO:0042985"(negative regulation of amyloid precursor protein biosynthetic process)|interpro:IPR007084(BRICHOS)|interpro:IPR040145|mint:Q5XIE8|refseq:NP_001006964.1|rgd:620727	rgd:2263|refseq:NP_036651.1|ensembl:ENSRNOG00000011589(gene)|ensembl:ENSRNOT00000016026(transcript)|ensembl:ENSRNOT00000068198(transcript)|go:"GO:0000082"(G1/S transition of mitotic cell cycle)|go:"GO:0001666"(response to hypoxia)|go:"GO:0002028"(regulation of sodium ion transport)|go:"GO:0003254"(regulation of membrane depolarization)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0004683"(calmodulin-dependent protein kinase activity)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005954"(calcium- and calmodulin-dependent protein kinase complex)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0006816"(calcium ion transport)|go:"GO:0010613"(positive regulation of cardiac muscle hypertrophy)|go:"GO:0010649"(regulation of cell communication by electrical coupling)|go:"GO:0010666"(positive regulation of cardiac muscle cell apoptotic process)|go:"GO:0010880"(regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum)|go:"GO:0010881"(regulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion)|go:"GO:0010971"(positive regulation of G2/M transition of mitotic cell cycle)|go:"GO:2000573"(positive regulation of DNA biosynthetic process)|go:"GO:0014704"(intercalated disc)|go:"GO:0014911"(positive regulation of smooth muscle cell migration)|go:"GO:0018105"(peptidyl-serine phosphorylation)|go:"GO:0018107"(peptidyl-threonine phosphorylation)|go:"GO:0019871"(sodium channel inhibitor activity)|go:"GO:0030007"(cellular potassium ion homeostasis)|go:"GO:0030315"(T-tubule)|go:"GO:0031432"(titin binding)|go:"GO:0031594"(neuromuscular junction)|go:"GO:0032469"(endoplasmic reticulum calcium ion homeostasis)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033017"(sarcoplasmic reticulum membrane)|go:"GO:0035022"(positive regulation of Rac protein signal transduction)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043005"(neuron projection)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043194"(axon initial segment)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0050998"(nitric-oxide synthase binding)|go:"GO:0055119"(relaxation of cardiac muscle)|go:"GO:0060048"(cardiac muscle contraction)|go:"GO:0060341"(regulation of cellular localization)|go:"GO:0061049"(cell growth involved in cardiac muscle cell development)|go:"GO:0070374"(positive regulation of ERK1 and ERK2 cascade)|go:"GO:0086003"(cardiac muscle cell contraction)|go:"GO:0098901"(regulation of cardiac muscle cell action potential)|go:"GO:0098909"(regulation of cardiac muscle cell action potential involved in regulation of contraction)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:1901844"(regulation of cell communication by electrical coupling involved in cardiac conduction)|go:"GO:1901897"(regulation of relaxation of cardiac muscle)|go:"GO:1902306"(negative regulation of sodium ion transmembrane transport)|go:"GO:1902514"(regulation of calcium ion transmembrane transport via high voltage-gated calcium channel)|go:"GO:1903076"(regulation of protein localization to plasma membrane)|go:"GO:1904707"(positive regulation of vascular associated smooth muscle cell proliferation)|refseq:XP_017446093.1|refseq:XP_017446094.1|refseq:XP_017446095.1|refseq:XP_017446099.1|refseq:XP_017446100.1|refseq:XP_017446102.1|refseq:XP_017446106.1|reactome:R-RNO-5576892|reactome:R-RNO-5578775|reactome:R-RNO-5673000|reactome:R-RNO-5673001|reactome:R-RNO-877300|reactome:R-RNO-936837|go:"GO:2000650"(negative regulation of sodium ion transmembrane transporter activity)|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR013543(Calcium/calmodulin dependent protein kinase II, association-domain)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR032710|mint:P15791|reactome:R-RNO-3371571|reactome:R-RNO-399719|reactome:R-RNO-438066	-	-	-	figure legend:st1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10116(rat-brain-cortex)|taxid:10116(Rattus norvegicus brain cortex)	-	2020/10/30	2020/10/30	rogid:DtE+ZXAZKdCMvUW5K+jXQ5bH07M10116	rogid:DrskswXp/QJHvHXeG0tWWxxV2K810116	rigid:3wclwrjZRvafcOruQOYnegkn54c	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q5XIE8	uniprotkb:P23358	intact:EBI-15348306|ensembl:ENSRNOP00000023037	intact:EBI-916883|ensembl:ENSRNOP00000041462	psi-mi:itm2b_rat(display_long)|uniprotkb:Itm2b(gene name)|psi-mi:Itm2b(display_short)|uniprotkb:Immature BRI2(gene name synonym)|uniprotkb:Transmembrane protein BRI(gene name synonym)	psi-mi:rl12_rat(display_long)|uniprotkb:Rpl12(gene name)|psi-mi:Rpl12(display_short)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Martins et al. (2018)	imex:IM-28469|pubmed:29476059	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26439741|imex:IM-28469-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSRNOG00000016271(gene)|ensembl:ENSRNOT00000023037(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001540"(amyloid-beta binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0010008"(endosome membrane)|go:"GO:0030660"(Golgi-associated vesicle membrane)|go:"GO:0031301"(integral component of organelle membrane)|go:"GO:0042985"(negative regulation of amyloid precursor protein biosynthetic process)|interpro:IPR007084(BRICHOS)|interpro:IPR040145|mint:Q5XIE8|refseq:NP_001006964.1|rgd:620727	rgd:1565106|refseq:NP_001102668.1|refseq:XP_006227318.1|refseq:XP_006256697.1|ensembl:ENSRNOG00000028993(gene)|ensembl:ENSRNOT00000042736(transcript)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005634"(nucleus)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006412"(translation)|go:"GO:0014069"(postsynaptic density)|go:"GO:0015934"(large ribosomal subunit)|go:"GO:0022625"(cytosolic large ribosomal subunit)|go:"GO:0022626"(cytosolic ribosome)|go:"GO:0045901"(positive regulation of translational elongation)|go:"GO:0070180"(large ribosomal subunit rRNA binding)|interpro:IPR000911(Ribosomal protein L11)|interpro:IPR020783|interpro:IPR020784|interpro:IPR020785|interpro:IPR036769|interpro:IPR036796|mint:P23358|reactome:R-RNO-156827|reactome:R-RNO-1799339|reactome:R-RNO-6791226|reactome:R-RNO-72689|reactome:R-RNO-72706|reactome:R-RNO-975956|reactome:R-RNO-975957	-	-	-	figure legend:st1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10116(rat-brain-cortex)|taxid:10116(Rattus norvegicus brain cortex)	-	2020/10/30	2020/10/30	rogid:DtE+ZXAZKdCMvUW5K+jXQ5bH07M10116	rogid:HD3+OCF6/IffH5e5AZRD235vais10116	rigid:3wclwrjZRvafcOruQOYnegkn54c	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q5XIE8	uniprotkb:Q9QUL6	intact:EBI-15348306|ensembl:ENSRNOP00000023037	intact:EBI-925794	psi-mi:itm2b_rat(display_long)|uniprotkb:Itm2b(gene name)|psi-mi:Itm2b(display_short)|uniprotkb:Immature BRI2(gene name synonym)|uniprotkb:Transmembrane protein BRI(gene name synonym)	psi-mi:nsf_rat(display_long)|uniprotkb:Nsf(gene name)|psi-mi:Nsf(display_short)|uniprotkb:Erg1(gene name synonym)|uniprotkb:N-ethylmaleimide-sensitive fusion protein(gene name synonym)|uniprotkb:Vesicular-fusion protein NSF(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Martins et al. (2018)	imex:IM-28469|pubmed:29476059	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26439741|imex:IM-28469-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSRNOG00000016271(gene)|ensembl:ENSRNOT00000023037(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001540"(amyloid-beta binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0010008"(endosome membrane)|go:"GO:0030660"(Golgi-associated vesicle membrane)|go:"GO:0031301"(integral component of organelle membrane)|go:"GO:0042985"(negative regulation of amyloid precursor protein biosynthetic process)|interpro:IPR007084(BRICHOS)|interpro:IPR040145|mint:Q5XIE8|refseq:NP_001006964.1|rgd:620727	rgd:621594|refseq:NP_068516.1|interpro:IPR009010(Aspartate decarboxylase-like fold)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR003959(AAA ATPase, core)|interpro:IPR003960(AAA ATPase, conserved site)|interpro:IPR003338(AAA ATPase VAT, N-terminal)|interpro:IPR004201(Cell division protein 48, CDC48, domain 2)|interpro:IPR027417|interpro:IPR029067|mint:Q9QUL6|interpro:IPR039812|interpro:IPR041569|go:"GO:0000149"(SNARE binding)|go:"GO:0001921"(positive regulation of receptor recycling)|go:"GO:0002090"(regulation of receptor internalization)|go:"GO:0005524"(ATP binding)|go:"GO:0005795"(Golgi stack)|go:"GO:0005886"(plasma membrane)|go:"GO:0006813"(potassium ion transport)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006891"(intra-Golgi vesicle-mediated transport)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0014069"(postsynaptic density)|go:"GO:0015031"(protein transport)|go:"GO:0016192"(vesicle-mediated transport)|go:"GO:0017075"(syntaxin-1 binding)|go:"GO:0017157"(regulation of exocytosis)|go:"GO:0019901"(protein kinase binding)|go:"GO:0019905"(syntaxin binding)|go:"GO:0030165"(PDZ domain binding)|go:"GO:0031267"(small GTPase binding)|go:"GO:0031748"(D1 dopamine receptor binding)|go:"GO:0032984"(protein-containing complex disassembly)|go:"GO:0035255"(ionotropic glutamate receptor binding)|go:"GO:0035494"(SNARE complex disassembly)|go:"GO:0043001"(Golgi to plasma membrane protein transport)|go:"GO:0043008"(ATP-dependent protein binding)|go:"GO:0043198"(dendritic shaft)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045732"(positive regulation of protein catabolic process)|go:"GO:0046872"(metal ion binding)|go:"GO:0048211"(Golgi vesicle docking)|go:"GO:0140545"(protein disaggregase activity)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|reactome:R-RNO-204005|reactome:R-RNO-416993|reactome:R-RNO-6807878|reactome:R-RNO-6811434|reactome:R-RNO-6811438|reactome:R-RNO-6811440	-	-	-	figure legend:st1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10116(rat-brain-cortex)|taxid:10116(Rattus norvegicus brain cortex)	-	2020/10/30	2020/10/30	rogid:DtE+ZXAZKdCMvUW5K+jXQ5bH07M10116	rogid:auiPGWRTO2wORmMBlQZuzHooO+M10116	rigid:3wclwrjZRvafcOruQOYnegkn54c	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q5XIE8	uniprotkb:P69897	intact:EBI-15348306|ensembl:ENSRNOP00000023037	intact:EBI-350912|uniprotkb:P05218|uniprotkb:Q6P9X8|uniprotkb:Q9CY33|uniprotkb:Q8WUC1|ensembl:ENSRNOP00000075269	psi-mi:itm2b_rat(display_long)|uniprotkb:Itm2b(gene name)|psi-mi:Itm2b(display_short)|uniprotkb:Immature BRI2(gene name synonym)|uniprotkb:Transmembrane protein BRI(gene name synonym)	psi-mi:tbb5_rat(display_long)|uniprotkb:Tubb5(gene name)|psi-mi:Tubb5(display_short)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Martins et al. (2018)	imex:IM-28469|pubmed:29476059	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26439741|imex:IM-28469-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSRNOG00000016271(gene)|ensembl:ENSRNOT00000023037(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001540"(amyloid-beta binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0010008"(endosome membrane)|go:"GO:0030660"(Golgi-associated vesicle membrane)|go:"GO:0031301"(integral component of organelle membrane)|go:"GO:0042985"(negative regulation of amyloid precursor protein biosynthetic process)|interpro:IPR007084(BRICHOS)|interpro:IPR040145|mint:Q5XIE8|refseq:NP_001006964.1|rgd:620727	rgd:628596|refseq:NP_775125.1|go:"GO:0005634"(nucleus)|go:"GO:0005641"(nuclear envelope lumen)|go:"GO:0005737"(cytoplasm)|go:"GO:0005874"(microtubule)|go:"GO:0007017"(microtubule-based process)|go:"GO:0009987"(cellular process)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032794"(GTPase activating protein binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0036464"(cytoplasmic ribonucleoprotein granule)|go:"GO:0042288"(MHC class I protein binding)|go:"GO:0044297"(cell body)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045121"(membrane raft)|go:"GO:0050807"(regulation of synapse organization)|go:"GO:0051225"(spindle assembly)|interpro:IPR000217(Tubulin)|interpro:IPR002453(Beta tubulin)|go:"GO:0005525"(GTP binding)|interpro:IPR003008(Tubulin/FtsZ, GTPase)|interpro:IPR008280(Tubulin/FtsZ, C-terminal)|interpro:IPR013838(Beta tubulin, autoregulation binding site)|interpro:IPR017975|interpro:IPR018316|interpro:IPR023123|interpro:IPR036525|interpro:IPR037103|mint:P69897|reactome:R-RNO-2565942|reactome:R-RNO-380259|reactome:R-RNO-380270|reactome:R-RNO-380284|reactome:R-RNO-380320|reactome:R-RNO-5620912|reactome:R-RNO-6798695|reactome:R-RNO-8854518|ensembl:ENSRNOG00000061216(gene)|ensembl:ENSRNOT00000079854(transcript)|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0005200"(structural constituent of cytoskeleton)	-	-	-	figure legend:st1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10116(rat-brain-cortex)|taxid:10116(Rattus norvegicus brain cortex)	-	2020/10/30	2020/10/30	rogid:DtE+ZXAZKdCMvUW5K+jXQ5bH07M10116	rogid:B6pmb1dvCroZXGd/1Zazi+s72GA10116	rigid:3wclwrjZRvafcOruQOYnegkn54c	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q5XIE8	uniprotkb:Q6P9T8	intact:EBI-15348306|ensembl:ENSRNOP00000023037	intact:EBI-919099	psi-mi:itm2b_rat(display_long)|uniprotkb:Itm2b(gene name)|psi-mi:Itm2b(display_short)|uniprotkb:Immature BRI2(gene name synonym)|uniprotkb:Transmembrane protein BRI(gene name synonym)	psi-mi:tbb4b_rat(display_long)|uniprotkb:Tubb4b(gene name)|psi-mi:Tubb4b(display_short)|uniprotkb:Tubb2c(gene name synonym)|uniprotkb:Tubulin beta-2C chain(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Martins et al. (2018)	imex:IM-28469|pubmed:29476059	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26439741|imex:IM-28469-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSRNOG00000016271(gene)|ensembl:ENSRNOT00000023037(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001540"(amyloid-beta binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0010008"(endosome membrane)|go:"GO:0030660"(Golgi-associated vesicle membrane)|go:"GO:0031301"(integral component of organelle membrane)|go:"GO:0042985"(negative regulation of amyloid precursor protein biosynthetic process)|interpro:IPR007084(BRICHOS)|interpro:IPR040145|mint:Q5XIE8|refseq:NP_001006964.1|rgd:620727	interpro:IPR008280(Tubulin/FtsZ, C-terminal)|interpro:IPR000217(Tubulin)|interpro:IPR018316|interpro:IPR017975|interpro:IPR003008(Tubulin/FtsZ, GTPase)|rgd:735101|refseq:NP_954525.1|interpro:IPR013838(Beta tubulin, autoregulation binding site)|interpro:IPR002453(Beta tubulin)|interpro:IPR023123|mint:Q6P9T8|interpro:IPR036525|interpro:IPR037103|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0003725"(double-stranded RNA binding)|go:"GO:0005200"(structural constituent of cytoskeleton)|go:"GO:0005525"(GTP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005874"(microtubule)|reactome:R-RNO-190840|reactome:R-RNO-2132295|reactome:R-RNO-2467813|reactome:R-RNO-2500257|reactome:R-RNO-2565942|reactome:R-RNO-3371497|reactome:R-RNO-380259|reactome:R-RNO-380270|reactome:R-RNO-380284|reactome:R-RNO-380320|reactome:R-RNO-437239|reactome:R-RNO-5610787|reactome:R-RNO-5617833|reactome:R-RNO-5620912|reactome:R-RNO-5620924|reactome:R-RNO-5626467|reactome:R-RNO-5663220|reactome:R-RNO-6798695|reactome:R-RNO-6807878|reactome:R-RNO-6811434|reactome:R-RNO-6811436|reactome:R-RNO-68877|reactome:R-RNO-8852276|reactome:R-RNO-8854518|reactome:R-RNO-8955332|reactome:R-RNO-9646399|reactome:R-RNO-9648025|reactome:R-RNO-9668328|reactome:R-RNO-983189	-	-	-	figure legend:st1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10116(rat-brain-cortex)|taxid:10116(Rattus norvegicus brain cortex)	-	2020/10/30	2020/10/30	rogid:DtE+ZXAZKdCMvUW5K+jXQ5bH07M10116	rogid:1RJgLTml+eflSvmnOyLoI1pFFTc10116	rigid:3wclwrjZRvafcOruQOYnegkn54c	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q5XIE8	uniprotkb:Q4QRB4	intact:EBI-15348306|ensembl:ENSRNOP00000023037	intact:EBI-919537|uniprotkb:Q8K5B6|ensembl:ENSRNOP00000023452	psi-mi:itm2b_rat(display_long)|uniprotkb:Itm2b(gene name)|psi-mi:Itm2b(display_short)|uniprotkb:Immature BRI2(gene name synonym)|uniprotkb:Transmembrane protein BRI(gene name synonym)	psi-mi:tbb3_rat(display_long)|uniprotkb:Tubb3(gene name)|psi-mi:Tubb3(display_short)|uniprotkb:Neuron-specific class III beta-tubulin(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Martins et al. (2018)	imex:IM-28469|pubmed:29476059	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26439741|imex:IM-28469-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSRNOG00000016271(gene)|ensembl:ENSRNOT00000023037(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001540"(amyloid-beta binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0010008"(endosome membrane)|go:"GO:0030660"(Golgi-associated vesicle membrane)|go:"GO:0031301"(integral component of organelle membrane)|go:"GO:0042985"(negative regulation of amyloid precursor protein biosynthetic process)|interpro:IPR007084(BRICHOS)|interpro:IPR040145|mint:Q5XIE8|refseq:NP_001006964.1|rgd:620727	rgd:628595|refseq:NP_640347.2|ensembl:ENSRNOG00000017209(gene)|ensembl:ENSRNOT00000023452(transcript)|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0005200"(structural constituent of cytoskeleton)|go:"GO:0005525"(GTP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005874"(microtubule)|go:"GO:0007411"(axon guidance)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0030027"(lamellipodium)|go:"GO:0030175"(filopodium)|go:"GO:0030182"(neuron differentiation)|go:"GO:0030424"(axon)|go:"GO:0030425"(dendrite)|go:"GO:0030426"(growth cone)|go:"GO:0038007"(netrin-activated signaling pathway)|go:"GO:0042277"(peptide binding)|go:"GO:0043025"(neuronal cell body)|go:"GO:0071944"(cell periphery)|go:"GO:1990791"(dorsal root ganglion development)|go:"GO:1990890"(netrin receptor binding)|interpro:IPR000217(Tubulin)|interpro:IPR002453(Beta tubulin)|interpro:IPR003008(Tubulin/FtsZ, GTPase)|interpro:IPR008280(Tubulin/FtsZ, C-terminal)|interpro:IPR013838(Beta tubulin, autoregulation binding site)|interpro:IPR017975|interpro:IPR018316|interpro:IPR023123|interpro:IPR036525|interpro:IPR037103|mint:Q4QRB4|reactome:R-RNO-190840|reactome:R-RNO-2132295|reactome:R-RNO-2467813|reactome:R-RNO-2500257|reactome:R-RNO-3371497|reactome:R-RNO-380320|reactome:R-RNO-437239|reactome:R-RNO-5610787|reactome:R-RNO-5617833|reactome:R-RNO-5620924|reactome:R-RNO-5626467|reactome:R-RNO-5663220|reactome:R-RNO-6807878|reactome:R-RNO-6811434|reactome:R-RNO-6811436|reactome:R-RNO-68877|reactome:R-RNO-8852276|reactome:R-RNO-8955332|reactome:R-RNO-9646399|reactome:R-RNO-9648025|reactome:R-RNO-9668328|reactome:R-RNO-983189	-	-	-	figure legend:st1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10116(rat-brain-cortex)|taxid:10116(Rattus norvegicus brain cortex)	-	2020/10/30	2020/10/30	rogid:DtE+ZXAZKdCMvUW5K+jXQ5bH07M10116	rogid:KhUQ3YFdcJvjwoHGykl7dv90vX810116	rigid:3wclwrjZRvafcOruQOYnegkn54c	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q5XIE8	uniprotkb:P85108	intact:EBI-15348306|ensembl:ENSRNOP00000023037	intact:EBI-2696554|ensembl:ENSRNOP00000023611|ensembl:ENSRNOP00000071729	psi-mi:itm2b_rat(display_long)|uniprotkb:Itm2b(gene name)|psi-mi:Itm2b(display_short)|uniprotkb:Immature BRI2(gene name synonym)|uniprotkb:Transmembrane protein BRI(gene name synonym)	psi-mi:tbb2a_rat(display_long)|uniprotkb:Tubb2a(gene name)|psi-mi:Tubb2a(display_short)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Martins et al. (2018)	imex:IM-28469|pubmed:29476059	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26439741|imex:IM-28469-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSRNOG00000016271(gene)|ensembl:ENSRNOT00000023037(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001540"(amyloid-beta binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0010008"(endosome membrane)|go:"GO:0030660"(Golgi-associated vesicle membrane)|go:"GO:0031301"(integral component of organelle membrane)|go:"GO:0042985"(negative regulation of amyloid precursor protein biosynthetic process)|interpro:IPR007084(BRICHOS)|interpro:IPR040145|mint:Q5XIE8|refseq:NP_001006964.1|rgd:620727	rgd:1588452|refseq:NP_001102589.1|ensembl:ENSRNOG00000017558(gene)|ensembl:ENSRNOT00000023611(transcript)|ensembl:ENSRNOT00000086264(transcript)|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0001764"(neuron migration)|go:"GO:0005200"(structural constituent of cytoskeleton)|go:"GO:0005525"(GTP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005874"(microtubule)|interpro:IPR000217(Tubulin)|interpro:IPR002453(Beta tubulin)|interpro:IPR003008(Tubulin/FtsZ, GTPase)|interpro:IPR008280(Tubulin/FtsZ, C-terminal)|interpro:IPR013838(Beta tubulin, autoregulation binding site)|interpro:IPR017975|interpro:IPR018316|interpro:IPR023123|interpro:IPR036525|interpro:IPR037103|mint:P85108|reactome:R-RNO-190840|reactome:R-RNO-2132295|reactome:R-RNO-2467813|reactome:R-RNO-2500257|reactome:R-RNO-3371497|reactome:R-RNO-380320|reactome:R-RNO-437239|reactome:R-RNO-5610787|reactome:R-RNO-5617833|reactome:R-RNO-5620924|reactome:R-RNO-5626467|reactome:R-RNO-5663220|reactome:R-RNO-6807878|reactome:R-RNO-6811434|reactome:R-RNO-6811436|reactome:R-RNO-68877|reactome:R-RNO-8852276|reactome:R-RNO-8955332|reactome:R-RNO-9646399|reactome:R-RNO-9648025|reactome:R-RNO-9668328|reactome:R-RNO-983189	-	-	-	figure legend:st1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10116(rat-brain-cortex)|taxid:10116(Rattus norvegicus brain cortex)	-	2020/10/30	2020/10/30	rogid:DtE+ZXAZKdCMvUW5K+jXQ5bH07M10116	rogid:XN9uTGU0KxQjMod0AGnM+XJoHyk10116	rigid:3wclwrjZRvafcOruQOYnegkn54c	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q5XIE8	uniprotkb:Q5XIF6	intact:EBI-15348306|ensembl:ENSRNOP00000023037	intact:EBI-2255850|ensembl:ENSRNOP00000004797	psi-mi:itm2b_rat(display_long)|uniprotkb:Itm2b(gene name)|psi-mi:Itm2b(display_short)|uniprotkb:Immature BRI2(gene name synonym)|uniprotkb:Transmembrane protein BRI(gene name synonym)	psi-mi:tba4a_rat(display_long)|uniprotkb:Tuba4a(gene name)|psi-mi:Tuba4a(display_short)|uniprotkb:Tuba4(gene name synonym)|uniprotkb:Tubulin alpha-4 chain(gene name synonym)|uniprotkb:Alpha-tubulin 4(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Martins et al. (2018)	imex:IM-28469|pubmed:29476059	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26439741|imex:IM-28469-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSRNOG00000016271(gene)|ensembl:ENSRNOT00000023037(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001540"(amyloid-beta binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0010008"(endosome membrane)|go:"GO:0030660"(Golgi-associated vesicle membrane)|go:"GO:0031301"(integral component of organelle membrane)|go:"GO:0042985"(negative regulation of amyloid precursor protein biosynthetic process)|interpro:IPR007084(BRICHOS)|interpro:IPR040145|mint:Q5XIE8|refseq:NP_001006964.1|rgd:620727	rgd:1359623|refseq:NP_001007005.1|ensembl:ENSRNOG00000003597(gene)|ensembl:ENSRNOT00000004797(transcript)|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0005200"(structural constituent of cytoskeleton)|go:"GO:0005525"(GTP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005874"(microtubule)|go:"GO:0019899"(enzyme binding)|go:"GO:0019901"(protein kinase binding)|interpro:IPR000217(Tubulin)|interpro:IPR002452(Alpha tubulin)|interpro:IPR003008(Tubulin/FtsZ, GTPase)|interpro:IPR008280(Tubulin/FtsZ, C-terminal)|interpro:IPR017975|interpro:IPR018316|interpro:IPR023123|interpro:IPR036525|interpro:IPR037103|mint:Q5XIF6|reactome:R-RNO-114608|reactome:R-RNO-190840|reactome:R-RNO-2132295|reactome:R-RNO-2467813|reactome:R-RNO-2500257|reactome:R-RNO-2565942|reactome:R-RNO-3371497|reactome:R-RNO-380259|reactome:R-RNO-380270|reactome:R-RNO-380284|reactome:R-RNO-380320|reactome:R-RNO-437239|reactome:R-RNO-5610787|reactome:R-RNO-5617833|reactome:R-RNO-5620912|reactome:R-RNO-5620924|reactome:R-RNO-5626467|reactome:R-RNO-5663220|reactome:R-RNO-6807878|reactome:R-RNO-6811434|reactome:R-RNO-6811436|reactome:R-RNO-68877|reactome:R-RNO-8852276|reactome:R-RNO-8854518|reactome:R-RNO-8955332|reactome:R-RNO-9646399|reactome:R-RNO-9648025|reactome:R-RNO-9668328|reactome:R-RNO-983189	-	-	-	figure legend:st1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10116(rat-brain-cortex)|taxid:10116(Rattus norvegicus brain cortex)	-	2020/10/30	2020/10/30	rogid:DtE+ZXAZKdCMvUW5K+jXQ5bH07M10116	rogid:6Oj9O8u7E6cLUJ1eT6y5slbk7uQ10116	rigid:3wclwrjZRvafcOruQOYnegkn54c	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q5XIE8	uniprotkb:P68370	intact:EBI-15348306|ensembl:ENSRNOP00000023037	intact:EBI-349571|uniprotkb:P02551|uniprotkb:P05210|uniprotkb:P05212|uniprotkb:Q6P6G6|ensembl:ENSRNOP00000075232	psi-mi:itm2b_rat(display_long)|uniprotkb:Itm2b(gene name)|psi-mi:Itm2b(display_short)|uniprotkb:Immature BRI2(gene name synonym)|uniprotkb:Transmembrane protein BRI(gene name synonym)	psi-mi:tba1a_rat(display_long)|uniprotkb:Tuba1a(gene name)|psi-mi:Tuba1a(display_short)|uniprotkb:Tuba1(gene name synonym)|uniprotkb:Tubulin alpha-1 chain(gene name synonym)|uniprotkb:Alpha-tubulin 1(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Martins et al. (2018)	imex:IM-28469|pubmed:29476059	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26439741|imex:IM-28469-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSRNOG00000016271(gene)|ensembl:ENSRNOT00000023037(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001540"(amyloid-beta binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0010008"(endosome membrane)|go:"GO:0030660"(Golgi-associated vesicle membrane)|go:"GO:0031301"(integral component of organelle membrane)|go:"GO:0042985"(negative regulation of amyloid precursor protein biosynthetic process)|interpro:IPR007084(BRICHOS)|interpro:IPR040145|mint:Q5XIE8|refseq:NP_001006964.1|rgd:620727	rgd:619717|refseq:NP_071634.1|go:"GO:0005200"(structural constituent of cytoskeleton)|go:"GO:0005525"(GTP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005874"(microtubule)|go:"GO:0005881"(cytoplasmic microtubule)|go:"GO:0007017"(microtubule-based process)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0031594"(neuromuscular junction)|go:"GO:0036464"(cytoplasmic ribonucleoprotein granule)|go:"GO:0042802"(identical protein binding)|go:"GO:0043209"(myelin sheath)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045121"(membrane raft)|go:"GO:0050807"(regulation of synapse organization)|go:"GO:0055037"(recycling endosome)|interpro:IPR000217(Tubulin)|interpro:IPR002452(Alpha tubulin)|interpro:IPR003008(Tubulin/FtsZ, GTPase)|interpro:IPR008280(Tubulin/FtsZ, C-terminal)|interpro:IPR017975|interpro:IPR018316|ensembl:ENSRNOG00000060728(gene)|ensembl:ENSRNOT00000083156(transcript)|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0000278"(mitotic cell cycle)|interpro:IPR023123|interpro:IPR036525|interpro:IPR037103|mint:P68370|reactome:R-RNO-190840|reactome:R-RNO-2132295|reactome:R-RNO-2467813|reactome:R-RNO-2500257|reactome:R-RNO-2565942|reactome:R-RNO-3371497|reactome:R-RNO-380259|reactome:R-RNO-380270|reactome:R-RNO-380284|reactome:R-RNO-380320|reactome:R-RNO-437239|reactome:R-RNO-5610787|reactome:R-RNO-5617833|reactome:R-RNO-5620912|reactome:R-RNO-5620924|reactome:R-RNO-5626467|reactome:R-RNO-5663220|reactome:R-RNO-6807878|reactome:R-RNO-6811434|reactome:R-RNO-6811436|reactome:R-RNO-68877|reactome:R-RNO-8852276|reactome:R-RNO-8854518|reactome:R-RNO-8955332|reactome:R-RNO-9646399|reactome:R-RNO-9648025|reactome:R-RNO-9668328|reactome:R-RNO-983189	-	-	-	figure legend:st1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10116(rat-brain-cortex)|taxid:10116(Rattus norvegicus brain cortex)	-	2020/10/30	2020/10/30	rogid:DtE+ZXAZKdCMvUW5K+jXQ5bH07M10116	rogid:1CzEzrf5y8hrQRPKgWQS1Wm1aCY10116	rigid:3wclwrjZRvafcOruQOYnegkn54c	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q5XIE8	uniprotkb:Q68A21	intact:EBI-15348306|ensembl:ENSRNOP00000023037	intact:EBI-26437870	psi-mi:itm2b_rat(display_long)|uniprotkb:Itm2b(gene name)|psi-mi:Itm2b(display_short)|uniprotkb:Immature BRI2(gene name synonym)|uniprotkb:Transmembrane protein BRI(gene name synonym)	psi-mi:purb_rat(display_long)|uniprotkb:Purb(gene name)|psi-mi:Purb(display_short)|uniprotkb:Purine-rich element-binding protein B(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Martins et al. (2018)	imex:IM-28469|pubmed:29476059	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26439741|imex:IM-28469-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSRNOG00000016271(gene)|ensembl:ENSRNOT00000023037(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001540"(amyloid-beta binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0010008"(endosome membrane)|go:"GO:0030660"(Golgi-associated vesicle membrane)|go:"GO:0031301"(integral component of organelle membrane)|go:"GO:0042985"(negative regulation of amyloid precursor protein biosynthetic process)|interpro:IPR007084(BRICHOS)|interpro:IPR040145|mint:Q5XIE8|refseq:NP_001006964.1|rgd:620727	go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0046332"(SMAD binding)|go:"GO:0140297"(DNA-binding transcription factor binding)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000900"(translation repressor activity, mRNA regulatory element binding)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0008283"(cell population proliferation)|go:"GO:0030154"(cell differentiation)|go:"GO:0032422"(purine-rich negative regulatory element binding)|mint:Q68A21|refseq:NP_001017503.1|interpro:IPR006628(PUR-alpha/beta/gamma, DNA/RNA-binding)|interpro:IPR030499|rgd:1559465	-	-	-	figure legend:st1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10116(rat-brain-cortex)|taxid:10116(Rattus norvegicus brain cortex)	-	2020/10/30	2020/10/30	rogid:DtE+ZXAZKdCMvUW5K+jXQ5bH07M10116	rogid:C/1C29JkX6J5Sb4qhdTIrNfNsAQ10116	rigid:3wclwrjZRvafcOruQOYnegkn54c	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q5XIE8	uniprotkb:Q05546	intact:EBI-15348306|ensembl:ENSRNOP00000023037	intact:EBI-1039732	psi-mi:itm2b_rat(display_long)|uniprotkb:Itm2b(gene name)|psi-mi:Itm2b(display_short)|uniprotkb:Immature BRI2(gene name synonym)|uniprotkb:Transmembrane protein BRI(gene name synonym)	psi-mi:tenr_rat(display_long)|uniprotkb:Tnr(gene name)|psi-mi:Tnr(display_short)|uniprotkb:Restrictin(gene name synonym)|uniprotkb:Janusin(gene name synonym)|uniprotkb:Neural recognition molecule J1-160/180(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Martins et al. (2018)	imex:IM-28469|pubmed:29476059	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26439741|imex:IM-28469-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSRNOG00000016271(gene)|ensembl:ENSRNOT00000023037(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001540"(amyloid-beta binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0010008"(endosome membrane)|go:"GO:0030660"(Golgi-associated vesicle membrane)|go:"GO:0031301"(integral component of organelle membrane)|go:"GO:0042985"(negative regulation of amyloid precursor protein biosynthetic process)|interpro:IPR007084(BRICHOS)|interpro:IPR040145|mint:Q5XIE8|refseq:NP_001006964.1|rgd:620727	rgd:3886|refseq:NP_037177.1|interpro:IPR002181(Fibrinogen, alpha/beta/gamma chain, C-terminal globular)|interpro:IPR003961(Fibronectin, type III)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR033079|interpro:IPR014716(Fibrinogen, alpha/beta/gamma chain, C-terminal globular, subdomain 1)|mint:Q05546|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005178"(integrin binding)|go:"GO:0005615"(extracellular space)|go:"GO:0007155"(cell adhesion)|go:"GO:0007158"(neuron cell-cell adhesion)|go:"GO:0007162"(negative regulation of cell adhesion)|go:"GO:0007399"(nervous system development)|go:"GO:0008306"(associative learning)|go:"GO:0009986"(cell surface)|go:"GO:0010977"(negative regulation of neuron projection development)|go:"GO:0022029"(telencephalon cell migration)|go:"GO:0022408"(negative regulation of cell-cell adhesion)|go:"GO:0030198"(extracellular matrix organization)|go:"GO:0030517"(negative regulation of axon extension)|go:"GO:0031012"(extracellular matrix)|go:"GO:0035641"(locomotory exploration behavior)|go:"GO:0045121"(membrane raft)|go:"GO:0048692"(negative regulation of axon extension involved in regeneration)|go:"GO:0050804"(modulation of chemical synaptic transmission)|go:"GO:0050805"(negative regulation of synaptic transmission)|go:"GO:0050808"(synapse organization)|go:"GO:0050885"(neuromuscular process controlling balance)|go:"GO:0051968"(positive regulation of synaptic transmission, glutamatergic)|go:"GO:0051971"(positive regulation of transmission of nerve impulse)|go:"GO:0060291"(long-term synaptic potentiation)|go:"GO:0062023"(collagen-containing extracellular matrix)|go:"GO:0072534"(perineuronal net)|go:"GO:0098685"(Schaffer collateral - CA1 synapse)|go:"GO:0098686"(hippocampal mossy fiber to CA3 synapse)|go:"GO:0098966"(perisynaptic extracellular matrix)|go:"GO:0098978"(glutamatergic synapse)|rcsb pdb:1TDQ|reactome:R-RNO-3000178|interpro:IPR000742(EGF-like, type 3)|interpro:IPR036056|interpro:IPR036116|interpro:IPR041161	-	-	-	figure legend:st1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10116(rat-brain-cortex)|taxid:10116(Rattus norvegicus brain cortex)	-	2020/10/30	2020/10/30	rogid:DtE+ZXAZKdCMvUW5K+jXQ5bH07M10116	rogid:Z810KbeOItf8zwgtic+nWX8azEM10116	rigid:3wclwrjZRvafcOruQOYnegkn54c	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q5XIE8	uniprotkb:Q68FQ0	intact:EBI-15348306|ensembl:ENSRNOP00000023037	intact:EBI-931470|uniprotkb:Q6PCT4|ensembl:ENSRNOP00000015886	psi-mi:itm2b_rat(display_long)|uniprotkb:Itm2b(gene name)|psi-mi:Itm2b(display_short)|uniprotkb:Immature BRI2(gene name synonym)|uniprotkb:Transmembrane protein BRI(gene name synonym)	psi-mi:tcpe_rat(display_long)|uniprotkb:Cct5(gene name)|psi-mi:Cct5(display_short)|uniprotkb:CCT-epsilon(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Martins et al. (2018)	imex:IM-28469|pubmed:29476059	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26439741|imex:IM-28469-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSRNOG00000016271(gene)|ensembl:ENSRNOT00000023037(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001540"(amyloid-beta binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0010008"(endosome membrane)|go:"GO:0030660"(Golgi-associated vesicle membrane)|go:"GO:0031301"(integral component of organelle membrane)|go:"GO:0042985"(negative regulation of amyloid precursor protein biosynthetic process)|interpro:IPR007084(BRICHOS)|interpro:IPR040145|mint:Q5XIE8|refseq:NP_001006964.1|rgd:620727	rgd:735161|refseq:NP_001004078.1|ensembl:ENSRNOG00000011632(gene)|ensembl:ENSRNOT00000015886(transcript)|go:"GO:0003730"(mRNA 3'-UTR binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005813"(centrosome)|go:"GO:0005832"(chaperonin-containing T-complex)|go:"GO:0005874"(microtubule)|go:"GO:0006457"(protein folding)|go:"GO:0007339"(binding of sperm to zona pellucida)|go:"GO:0009615"(response to virus)|go:"GO:0031681"(G-protein beta-subunit binding)|go:"GO:0032212"(positive regulation of telomere maintenance via telomerase)|go:"GO:0044183"(protein folding chaperone)|go:"GO:0044297"(cell body)|go:"GO:0048027"(mRNA 5'-UTR binding)|go:"GO:0048487"(beta-tubulin binding)|go:"GO:0050821"(protein stabilization)|go:"GO:0051082"(unfolded protein binding)|go:"GO:1901998"(toxin transport)|go:"GO:1904851"(positive regulation of establishment of protein localization to telomere)|interpro:IPR002194(Chaperonin TCP-1, conserved site)|interpro:IPR002423(Chaperonin Cpn60/TCP-1)|interpro:IPR012718(T-complex protein 1, epsilon subunit)|interpro:IPR017998|interpro:IPR027409|interpro:IPR027410|interpro:IPR027413|mint:Q68FQ0|reactome:R-RNO-390471|reactome:R-RNO-5620922|reactome:R-RNO-6814122	-	-	-	figure legend:st1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10116(rat-brain-cortex)|taxid:10116(Rattus norvegicus brain cortex)	-	2020/10/30	2020/10/30	rogid:DtE+ZXAZKdCMvUW5K+jXQ5bH07M10116	rogid:ABW24Esuv9oCZYZr+++2wlVSTcI10116	rigid:3wclwrjZRvafcOruQOYnegkn54c	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q5XIE8	uniprotkb:P61265	intact:EBI-15348306|ensembl:ENSRNOP00000023037	intact:EBI-2255905|uniprotkb:P32853|ensembl:ENSRNOP00000026063	psi-mi:itm2b_rat(display_long)|uniprotkb:Itm2b(gene name)|psi-mi:Itm2b(display_short)|uniprotkb:Immature BRI2(gene name synonym)|uniprotkb:Transmembrane protein BRI(gene name synonym)	psi-mi:stx1b_rat(display_long)|uniprotkb:Stx1b(gene name)|psi-mi:Stx1b(display_short)|uniprotkb:Stx1b2(gene name synonym)|uniprotkb:Syntaxin-1B2(gene name synonym)|uniprotkb:P35B(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Martins et al. (2018)	imex:IM-28469|pubmed:29476059	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26439741|imex:IM-28469-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSRNOG00000016271(gene)|ensembl:ENSRNOT00000023037(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001540"(amyloid-beta binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0010008"(endosome membrane)|go:"GO:0030660"(Golgi-associated vesicle membrane)|go:"GO:0031301"(integral component of organelle membrane)|go:"GO:0042985"(negative regulation of amyloid precursor protein biosynthetic process)|interpro:IPR007084(BRICHOS)|interpro:IPR040145|mint:Q5XIE8|refseq:NP_001006964.1|rgd:620727	rgd:3784|refseq:NP_036832.1|go:"GO:0016079"(synaptic vesicle exocytosis)|go:"GO:0016081"(synaptic vesicle docking)|go:"GO:0016192"(vesicle-mediated transport)|go:"GO:0017157"(regulation of exocytosis)|go:"GO:0019901"(protein kinase binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030424"(axon)|go:"GO:0031201"(SNARE complex)|go:"GO:0031594"(neuromuscular junction)|go:"GO:0031629"(synaptic vesicle fusion to presynaptic active zone membrane)|go:"GO:0042734"(presynaptic membrane)|go:"GO:0048278"(vesicle docking)|go:"GO:0048787"(presynaptic active zone membrane)|go:"GO:0048791"(calcium ion-regulated exocytosis of neurotransmitter)|go:"GO:0060025"(regulation of synaptic activity)|go:"GO:0061669"(spontaneous neurotransmitter secretion)|go:"GO:0072657"(protein localization to membrane)|go:"GO:0098793"(presynapse)|go:"GO:0098967"(exocytic insertion of neurotransmitter receptor to postsynaptic membrane)|go:"GO:1903422"(negative regulation of synaptic vesicle recycling)|go:"GO:1904050"(positive regulation of spontaneous neurotransmitter secretion)|go:"GO:1905302"(negative regulation of macropinocytosis)|go:"GO:2000463"(positive regulation of excitatory postsynaptic potential)|interpro:IPR000727(Target SNARE coiled-coil region)|interpro:IPR006011(Syntaxin, N-terminal)|interpro:IPR006012(Syntaxin/epimorphin, conserved site)|interpro:IPR010989(t-SNARE)|interpro:IPR028669|mint:P61265|reactome:R-RNO-5682910|ensembl:ENSRNOG00000019193(gene)|ensembl:ENSRNOT00000026063(transcript)|go:"GO:0000149"(SNARE binding)|go:"GO:0001956"(positive regulation of neurotransmitter secretion)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005484"(SNAP receptor activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006887"(exocytosis)|go:"GO:0006904"(vesicle docking involved in exocytosis)|go:"GO:0006906"(vesicle fusion)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0010807"(regulation of synaptic vesicle priming)|go:"GO:0010977"(negative regulation of neuron projection development)|go:"GO:0012505"(endomembrane system)|go:"GO:0015031"(protein transport)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)	-	-	-	figure legend:st1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10116(rat-brain-cortex)|taxid:10116(Rattus norvegicus brain cortex)	-	2020/10/30	2020/10/30	rogid:DtE+ZXAZKdCMvUW5K+jXQ5bH07M10116	rogid:B3aWVxxX3lZ8hOYK4gxwZupY7g410116	rigid:3wclwrjZRvafcOruQOYnegkn54c	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q5XIE8	uniprotkb:P21707	intact:EBI-15348306|ensembl:ENSRNOP00000023037	intact:EBI-458098|uniprotkb:Q3S2E6|uniprotkb:Q707P5|ensembl:ENSRNOP00000049624|ensembl:ENSRNOP00000069194	psi-mi:itm2b_rat(display_long)|uniprotkb:Itm2b(gene name)|psi-mi:Itm2b(display_short)|uniprotkb:Immature BRI2(gene name synonym)|uniprotkb:Transmembrane protein BRI(gene name synonym)	psi-mi:syt1_rat(display_long)|uniprotkb:Syt1(gene name)|psi-mi:Syt1(display_short)|uniprotkb:Synaptotagmin I(gene name synonym)|uniprotkb:p65(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Martins et al. (2018)	imex:IM-28469|pubmed:29476059	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26439741|imex:IM-28469-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSRNOG00000016271(gene)|ensembl:ENSRNOT00000023037(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001540"(amyloid-beta binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0010008"(endosome membrane)|go:"GO:0030660"(Golgi-associated vesicle membrane)|go:"GO:0031301"(integral component of organelle membrane)|go:"GO:0042985"(negative regulation of amyloid precursor protein biosynthetic process)|interpro:IPR007084(BRICHOS)|interpro:IPR040145|mint:Q5XIE8|refseq:NP_001006964.1|rgd:620727	rgd:3803|refseq:NP_001028852.2|ensembl:ENSRNOG00000006426(gene)|ensembl:ENSRNOT00000048880(transcript)|ensembl:ENSRNOT00000088950(transcript)|go:"GO:0000149"(SNARE binding)|go:"GO:0001786"(phosphatidylserine binding)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005513"(detection of calcium ion)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005543"(phospholipid binding)|go:"GO:0005544"(calcium-dependent phospholipid binding)|go:"GO:0005546"(phosphatidylinositol-4,5-bisphosphate binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0007269"(neurotransmitter secretion)|go:"GO:0007420"(brain development)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0014059"(regulation of dopamine secretion)|go:"GO:0016079"(synaptic vesicle exocytosis)|go:"GO:0016192"(vesicle-mediated transport)|go:"GO:0017075"(syntaxin-1 binding)|go:"GO:0017156"(calcium-ion regulated exocytosis)|go:"GO:0017158"(regulation of calcium ion-dependent exocytosis)|go:"GO:0019905"(syntaxin binding)|go:"GO:0030141"(secretory granule)|go:"GO:0030154"(cell differentiation)|go:"GO:0030276"(clathrin binding)|go:"GO:0030285"(integral component of synaptic vesicle membrane)|go:"GO:0030348"(syntaxin-3 binding)|go:"GO:0030424"(axon)|go:"GO:0030672"(synaptic vesicle membrane)|go:"GO:0031045"(dense core granule)|go:"GO:0031340"(positive regulation of vesicle fusion)|go:"GO:0033603"(positive regulation of dopamine secretion)|go:"GO:0042584"(chromaffin granule membrane)|go:"GO:0042734"(presynaptic membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0043005"(neuron projection)|go:"GO:0043195"(terminal bouton)|go:"GO:0043229"(intracellular organelle)|go:"GO:0044306"(neuron projection terminus)|go:"GO:0045956"(positive regulation of calcium ion-dependent exocytosis)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0048278"(vesicle docking)|go:"GO:0048306"(calcium-dependent protein binding)|go:"GO:0048488"(synaptic vesicle endocytosis)|go:"GO:0048791"(calcium ion-regulated exocytosis of neurotransmitter)|go:"GO:0050750"(low-density lipoprotein particle receptor binding)|go:"GO:0050806"(positive regulation of synaptic transmission)|go:"GO:0051291"(protein heterooligomerization)|go:"GO:0051592"(response to calcium ion)|go:"GO:0051966"(regulation of synaptic transmission, glutamatergic)|go:"GO:0060076"(excitatory synapse)|go:"GO:0061669"(spontaneous neurotransmitter secretion)|go:"GO:0061891"(calcium ion sensor activity)|go:"GO:0070382"(exocytic vesicle)|go:"GO:0071277"(cellular response to calcium ion)|go:"GO:0071911"(synchronous neurotransmitter secretion)|go:"GO:0098686"(hippocampal mossy fiber to CA3 synapse)|go:"GO:0098746"(fast, calcium ion-dependent exocytosis of neurotransmitter)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099502"(calcium-dependent activation of synaptic vesicle fusion)|go:"GO:1903235"(positive regulation of calcium ion-dependent exocytosis of neurotransmitter)|go:"GO:1903305"(regulation of regulated secretory pathway)|go:"GO:1903861"(positive regulation of dendrite extension)|go:"GO:2000300"(regulation of synaptic vesicle exocytosis)|interpro:IPR000008(C2 calcium-dependent membrane targeting)|interpro:IPR001565(Synaptotagmin)|interpro:IPR015428(Synaptotagmin 1,2)|interpro:IPR035892|mint:P21707|rcsb pdb:1BYN|rcsb pdb:1K5W|rcsb pdb:1RSY|rcsb pdb:1TJM|rcsb pdb:1TJX|rcsb pdb:1UOV|rcsb pdb:1UOW|rcsb pdb:2YOA|rcsb pdb:4WEE|rcsb pdb:5CCG|rcsb pdb:5CCH|rcsb pdb:5CCI|rcsb pdb:5CCJ|rcsb pdb:5KJ7|rcsb pdb:5KJ8|rcsb pdb:5W5C|rcsb pdb:5W5D|rcsb pdb:6CXW|rcsb pdb:6MTI|reactome:R-RNO-181429|reactome:R-RNO-181430|reactome:R-RNO-210500|reactome:R-RNO-212676|reactome:R-RNO-264642|reactome:R-RNO-8856825|reactome:R-RNO-8856828|reactome:R-RNO-888590|refseq:XP_017450168.1|dip:DIP-29064N	-	-	-	figure legend:st1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10116(rat-brain-cortex)|taxid:10116(Rattus norvegicus brain cortex)	-	2020/10/30	2020/10/30	rogid:DtE+ZXAZKdCMvUW5K+jXQ5bH07M10116	rogid:fr7zfj22zAOY/bJ7psjrgnsb0g810116	rigid:3wclwrjZRvafcOruQOYnegkn54c	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q5XIE8	uniprotkb:Q02563	intact:EBI-15348306|ensembl:ENSRNOP00000023037	intact:EBI-466194|uniprotkb:Q58DZ8|ensembl:ENSRNOP00000028760	psi-mi:itm2b_rat(display_long)|uniprotkb:Itm2b(gene name)|psi-mi:Itm2b(display_short)|uniprotkb:Immature BRI2(gene name synonym)|uniprotkb:Transmembrane protein BRI(gene name synonym)	psi-mi:sv2a_rat(display_long)|uniprotkb:Sv2a(gene name)|psi-mi:Sv2a(display_short)|uniprotkb:Sv2(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Martins et al. (2018)	imex:IM-28469|pubmed:29476059	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26439741|imex:IM-28469-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSRNOG00000016271(gene)|ensembl:ENSRNOT00000023037(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001540"(amyloid-beta binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0010008"(endosome membrane)|go:"GO:0030660"(Golgi-associated vesicle membrane)|go:"GO:0031301"(integral component of organelle membrane)|go:"GO:0042985"(negative regulation of amyloid precursor protein biosynthetic process)|interpro:IPR007084(BRICHOS)|interpro:IPR040145|mint:Q5XIE8|refseq:NP_001006964.1|rgd:620727	rgd:619715|refseq:NP_476558.2|refseq:XP_006233014.1|ensembl:ENSRNOT00000028760(transcript)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005911"(cell-cell junction)|go:"GO:0006836"(neurotransmitter transport)|go:"GO:0006874"(cellular calcium ion homeostasis)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0014052"(regulation of gamma-aminobutyric acid secretion)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016082"(synaptic vesicle priming)|go:"GO:0019901"(protein kinase binding)|go:"GO:0022857"(transmembrane transporter activity)|go:"GO:0030285"(integral component of synaptic vesicle membrane)|go:"GO:0030425"(dendrite)|go:"GO:0030672"(synaptic vesicle membrane)|go:"GO:0031594"(neuromuscular junction)|go:"GO:0043005"(neuron projection)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043195"(terminal bouton)|go:"GO:0045202"(synapse)|go:"GO:0048786"(presynaptic active zone)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0098982"(GABA-ergic synapse)|interpro:IPR001646(Pentapeptide repeat)|interpro:IPR005828(General substrate transporter)|interpro:IPR005829(Sugar transporter, conserved site)|interpro:IPR011701(Major facilitator superfamily MFS-1)|interpro:IPR020846|interpro:IPR022308|interpro:IPR036259|mint:Q02563|ensembl:ENSRNOG00000021182(gene)	-	-	-	figure legend:st1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10116(rat-brain-cortex)|taxid:10116(Rattus norvegicus brain cortex)	-	2020/10/30	2020/10/30	rogid:DtE+ZXAZKdCMvUW5K+jXQ5bH07M10116	rogid:a7TA6gTNT5eWAIVLxjT1dgUQzn410116	rigid:3wclwrjZRvafcOruQOYnegkn54c	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q5XIE8	uniprotkb:P16086	intact:EBI-15348306|ensembl:ENSRNOP00000023037	intact:EBI-2255997|uniprotkb:O88663|uniprotkb:P70477|ensembl:ENSRNOP00000042382	psi-mi:itm2b_rat(display_long)|uniprotkb:Itm2b(gene name)|psi-mi:Itm2b(display_short)|uniprotkb:Immature BRI2(gene name synonym)|uniprotkb:Transmembrane protein BRI(gene name synonym)	psi-mi:sptn1_rat(display_long)|uniprotkb:Sptan1(gene name)|psi-mi:Sptan1(display_short)|uniprotkb:Spna2(gene name synonym)|uniprotkb:Spta2(gene name synonym)|uniprotkb:Alpha-II spectrin(gene name synonym)|uniprotkb:Fodrin alpha chain(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Martins et al. (2018)	imex:IM-28469|pubmed:29476059	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26439741|imex:IM-28469-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSRNOG00000016271(gene)|ensembl:ENSRNOT00000023037(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001540"(amyloid-beta binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0010008"(endosome membrane)|go:"GO:0030660"(Golgi-associated vesicle membrane)|go:"GO:0031301"(integral component of organelle membrane)|go:"GO:0042985"(negative regulation of amyloid precursor protein biosynthetic process)|interpro:IPR007084(BRICHOS)|interpro:IPR040145|mint:Q5XIE8|refseq:NP_001006964.1|rgd:620727	rgd:621714|refseq:NP_741984.2|ensembl:ENSRNOG00000015396(gene)|ensembl:ENSRNOT00000045827(transcript)|go:"GO:0003779"(actin binding)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005916"(fascia adherens)|go:"GO:0008091"(spectrin)|go:"GO:0016020"(membrane)|go:"GO:0016328"(lateral plasma membrane)|go:"GO:0019905"(syntaxin binding)|go:"GO:0030018"(Z disc)|go:"GO:0030507"(spectrin binding)|go:"GO:0030863"(cortical cytoskeleton)|go:"GO:0031532"(actin cytoskeleton reorganization)|go:"GO:0032437"(cuticular plate)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033270"(paranode region of axon)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0051693"(actin filament capping)|interpro:IPR001452(Src homology-3)|interpro:IPR002017(Spectrin repeat)|interpro:IPR002048(Calcium-binding EF-hand)|interpro:IPR011992(EF-Hand type)|interpro:IPR014837(EF-hand, Ca insensitive)|interpro:IPR018159|interpro:IPR018247|interpro:IPR035825|interpro:IPR036028|mint:P16086|rcsb pdb:3THK|reactome:R-RNO-264870|reactome:R-RNO-375165|reactome:R-RNO-445095|reactome:R-RNO-5673001|reactome:R-RNO-6798695|reactome:R-RNO-6807878|reactome:R-RNO-9013420|reactome:R-RNO-9013424	-	-	-	figure legend:st1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10116(rat-brain-cortex)|taxid:10116(Rattus norvegicus brain cortex)	-	2020/10/30	2020/10/30	rogid:DtE+ZXAZKdCMvUW5K+jXQ5bH07M10116	rogid:3Tj95Pgv62omEnsaMAG3bfLLXsM10116	rigid:3wclwrjZRvafcOruQOYnegkn54c	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q5XIE8	uniprotkb:P12346	intact:EBI-15348306|ensembl:ENSRNOP00000023037	intact:EBI-5748069|uniprotkb:Q63602|uniprotkb:Q64628|uniprotkb:Q64630|uniprotkb:Q7TNX0|ensembl:ENSRNOP00000045637	psi-mi:itm2b_rat(display_long)|uniprotkb:Itm2b(gene name)|psi-mi:Itm2b(display_short)|uniprotkb:Immature BRI2(gene name synonym)|uniprotkb:Transmembrane protein BRI(gene name synonym)	psi-mi:trfe_rat(display_long)|uniprotkb:Tf(gene name)|psi-mi:Tf(display_short)|uniprotkb:Beta-1 metal-binding globulin(gene name synonym)|uniprotkb:Liver regeneration-related protein LRRG03(gene name synonym)|uniprotkb:Siderophilin(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Martins et al. (2018)	imex:IM-28469|pubmed:29476059	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26439741|imex:IM-28469-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSRNOG00000016271(gene)|ensembl:ENSRNOT00000023037(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001540"(amyloid-beta binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0010008"(endosome membrane)|go:"GO:0030660"(Golgi-associated vesicle membrane)|go:"GO:0031301"(integral component of organelle membrane)|go:"GO:0042985"(negative regulation of amyloid precursor protein biosynthetic process)|interpro:IPR007084(BRICHOS)|interpro:IPR040145|mint:Q5XIE8|refseq:NP_001006964.1|rgd:620727	rgd:3845|refseq:NP_001013128.1|ensembl:ENSRNOG00000030625(gene)|ensembl:ENSRNOT00000045628(transcript)|go:"GO:0001666"(response to hypoxia)|go:"GO:0005576"(extracellular region)|go:"GO:0005604"(basement membrane)|go:"GO:0005615"(extracellular space)|go:"GO:0005768"(endosome)|go:"GO:0005769"(early endosome)|go:"GO:0005770"(late endosome)|go:"GO:0005886"(plasma membrane)|go:"GO:0005905"(clathrin-coated pit)|go:"GO:0006826"(iron ion transport)|go:"GO:0006879"(cellular iron ion homeostasis)|go:"GO:0006915"(apoptotic process)|go:"GO:0006953"(acute-phase response)|go:"GO:0007015"(actin filament organization)|go:"GO:0007257"(obsolete activation of JUN kinase activity)|go:"GO:0008198"(ferrous iron binding)|go:"GO:0008199"(ferric iron binding)|go:"GO:0009617"(response to bacterium)|go:"GO:0009925"(basal plasma membrane)|go:"GO:0009986"(cell surface)|go:"GO:0010288"(response to lead ion)|go:"GO:0014070"(response to organic cyclic compound)|go:"GO:0016020"(membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0019731"(antibacterial humoral response)|go:"GO:0030139"(endocytic vesicle)|go:"GO:0030316"(osteoclast differentiation)|go:"GO:0031232"(extrinsic component of external side of plasma membrane)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0031643"(positive regulation of myelination)|go:"GO:0031982"(vesicle)|go:"GO:0034756"(regulation of iron ion transport)|go:"GO:0034986"(iron chaperone activity)|go:"GO:0042327"(positive regulation of phosphorylation)|go:"GO:0045178"(basal part of cell)|go:"GO:0045780"(positive regulation of bone resorption)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0048260"(positive regulation of receptor-mediated endocytosis)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051286"(cell tip)|go:"GO:0055037"(recycling endosome)|go:"GO:0060395"(SMAD protein signal transduction)|go:"GO:0070371"(ERK1 and ERK2 cascade)|go:"GO:0070447"(positive regulation of oligodendrocyte progenitor proliferation)|go:"GO:0071281"(cellular response to iron ion)|go:"GO:0071320"(cellular response to cAMP)|go:"GO:0071372"(cellular response to follicle-stimulating hormone stimulus)|go:"GO:1990459"(transferrin receptor binding)|go:"GO:1990712"(HFE-transferrin receptor complex)|go:"GO:2000147"(positive regulation of cell motility)|interpro:IPR001156(Peptidase S60, transferrin lactoferrin)|interpro:IPR016357(Transferrin)|interpro:IPR018195|interpro:IPR030685|mint:P12346|reactome:R-RNO-114608|reactome:R-RNO-381426|reactome:R-RNO-8856825|reactome:R-RNO-8856828|reactome:R-RNO-8957275|reactome:R-RNO-917937|reactome:R-RNO-917977	-	-	-	figure legend:st1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10116(rat-brain-cortex)|taxid:10116(Rattus norvegicus brain cortex)	-	2020/10/30	2020/10/30	rogid:DtE+ZXAZKdCMvUW5K+jXQ5bH07M10116	rogid:9b+8HnYQbOkvBtuNUgHzhq2+cQ010116	rigid:3wclwrjZRvafcOruQOYnegkn54c	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q5XIE8	uniprotkb:Q6RJR6	intact:EBI-15348306|ensembl:ENSRNOP00000023037	intact:EBI-919246|uniprotkb:Q6P6R3|uniprotkb:Q8VBU0|ensembl:ENSRNOP00000028785	psi-mi:itm2b_rat(display_long)|uniprotkb:Itm2b(gene name)|psi-mi:Itm2b(display_short)|uniprotkb:Immature BRI2(gene name synonym)|uniprotkb:Transmembrane protein BRI(gene name synonym)	psi-mi:rtn3_rat(display_long)|uniprotkb:Rtn3(gene name)|psi-mi:Rtn3(display_short)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Martins et al. (2018)	imex:IM-28469|pubmed:29476059	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26439741|imex:IM-28469-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSRNOG00000016271(gene)|ensembl:ENSRNOT00000023037(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001540"(amyloid-beta binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0010008"(endosome membrane)|go:"GO:0030660"(Golgi-associated vesicle membrane)|go:"GO:0031301"(integral component of organelle membrane)|go:"GO:0042985"(negative regulation of amyloid precursor protein biosynthetic process)|interpro:IPR007084(BRICHOS)|interpro:IPR040145|mint:Q5XIE8|refseq:NP_001006964.1|rgd:620727	rgd:620988|refseq:NP_001009953.2|refseq:NP_543185.2|ensembl:ENSRNOG00000021202(gene)|ensembl:ENSRNOT00000028785(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0006915"(apoptotic process)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016192"(vesicle-mediated transport)|go:"GO:0045202"(synapse)|go:"GO:0071786"(endoplasmic reticulum tubular network organization)|go:"GO:0071787"(endoplasmic reticulum tubular network formation)|go:"GO:1902430"(negative regulation of amyloid-beta formation)|interpro:IPR003388(Reticulon)|mint:Q6RJR6|reactome:R-RNO-8849932	-	-	-	figure legend:st1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10116(rat-brain-cortex)|taxid:10116(Rattus norvegicus brain cortex)	-	2020/10/30	2020/10/30	rogid:DtE+ZXAZKdCMvUW5K+jXQ5bH07M10116	rogid:CehbzFUmpJjUrA42+RLJ+oKmx3A10116	rigid:3wclwrjZRvafcOruQOYnegkn54c	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q5XIE8	uniprotkb:Q64548	intact:EBI-15348306|ensembl:ENSRNOP00000023037	intact:EBI-26437852|uniprotkb:Q64547	psi-mi:itm2b_rat(display_long)|uniprotkb:Itm2b(gene name)|psi-mi:Itm2b(display_short)|uniprotkb:Immature BRI2(gene name synonym)|uniprotkb:Transmembrane protein BRI(gene name synonym)	psi-mi:rtn1_rat(display_long)|uniprotkb:Rtn1(gene name)|psi-mi:Rtn1(display_short)|uniprotkb:Nsp(gene name synonym)|uniprotkb:Neuroendocrine-specific protein(gene name synonym)|uniprotkb:S-rex(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Martins et al. (2018)	imex:IM-28469|pubmed:29476059	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26439741|imex:IM-28469-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSRNOG00000016271(gene)|ensembl:ENSRNOT00000023037(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001540"(amyloid-beta binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0010008"(endosome membrane)|go:"GO:0030660"(Golgi-associated vesicle membrane)|go:"GO:0031301"(integral component of organelle membrane)|go:"GO:0042985"(negative regulation of amyloid precursor protein biosynthetic process)|interpro:IPR007084(BRICHOS)|interpro:IPR040145|mint:Q5XIE8|refseq:NP_001006964.1|rgd:620727	go:"GO:0000139"(Golgi membrane)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005790"(smooth endoplasmic reticulum)|go:"GO:0016021"(integral component of membrane)|go:"GO:1902430"(negative regulation of amyloid-beta formation)|mint:Q64548|refseq:NP_446317.1|refseq:XP_008762912.1|interpro:IPR003388(Reticulon)|rgd:620986	-	-	-	figure legend:st1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10116(rat-brain-cortex)|taxid:10116(Rattus norvegicus brain cortex)	-	2020/10/30	2020/10/30	rogid:DtE+ZXAZKdCMvUW5K+jXQ5bH07M10116	rogid:GR15tCaopATHPIxGwl20b04sG4c10116	rigid:3wclwrjZRvafcOruQOYnegkn54c	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q5XIE8	uniprotkb:P63012	intact:EBI-15348306|ensembl:ENSRNOP00000023037	intact:EBI-440126|ensembl:ENSRNOP00000026392|uniprotkb:P05713	psi-mi:itm2b_rat(display_long)|uniprotkb:Itm2b(gene name)|psi-mi:Itm2b(display_short)|uniprotkb:Immature BRI2(gene name synonym)|uniprotkb:Transmembrane protein BRI(gene name synonym)	psi-mi:rab3a_rat(display_long)|uniprotkb:Rab3a(gene name)|psi-mi:Rab3a(display_short)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Martins et al. (2018)	imex:IM-28469|pubmed:29476059	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26439741|imex:IM-28469-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSRNOG00000016271(gene)|ensembl:ENSRNOT00000023037(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001540"(amyloid-beta binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0010008"(endosome membrane)|go:"GO:0030660"(Golgi-associated vesicle membrane)|go:"GO:0031301"(integral component of organelle membrane)|go:"GO:0042985"(negative regulation of amyloid precursor protein biosynthetic process)|interpro:IPR007084(BRICHOS)|interpro:IPR040145|mint:Q5XIE8|refseq:NP_001006964.1|rgd:620727	ensembl:ENSRNOT00000026391(transcript)|go:"GO:0001669"(acrosomal vesicle)|go:"GO:0001671"(ATPase activator activity)|go:"GO:0001778"(plasma membrane repair)|go:"GO:0003016"(respiratory system process)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005764"(lysosome)|go:"GO:0005768"(endosome)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006887"(exocytosis)|go:"GO:0006904"(vesicle docking involved in exocytosis)|go:"GO:0007005"(mitochondrion organization)|go:"GO:0007274"(neuromuscular synaptic transmission)|go:"GO:0007409"(axonogenesis)|ensembl:ENSRNOG00000019433(gene)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0009306"(protein secretion)|go:"GO:0009791"(post-embryonic development)|go:"GO:0010807"(regulation of synaptic vesicle priming)|go:"GO:0014059"(regulation of dopamine secretion)|go:"GO:0016020"(membrane)|go:"GO:0016079"(synaptic vesicle exocytosis)|go:"GO:0016188"(synaptic vesicle maturation)|go:"GO:0017156"(calcium-ion regulated exocytosis)|go:"GO:0017157"(regulation of exocytosis)|go:"GO:0030141"(secretory granule)|go:"GO:0030324"(lung development)|go:"GO:0030424"(axon)|go:"GO:0030742"(GTP-dependent protein binding)|go:"GO:0031489"(myosin V binding)|go:"GO:0031630"(regulation of synaptic vesicle fusion to presynaptic active zone membrane)|go:"GO:0032418"(lysosome localization)|go:"GO:0032482"(Rab protein signal transduction)|go:"GO:0032991"(protein-containing complex)|go:"GO:0036465"(synaptic vesicle recycling)|go:"GO:0043195"(terminal bouton)|go:"GO:0043229"(intracellular organelle)|go:"GO:0045055"(regulated exocytosis)|go:"GO:0048172"(regulation of short-term neuronal synaptic plasticity)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0048489"(synaptic vesicle transport)|go:"GO:0048786"(presynaptic active zone)|go:"GO:0048790"(maintenance of presynaptic active zone structure)|go:"GO:0050975"(sensory perception of touch)|go:"GO:0051021"(GDP-dissociation inhibitor binding)|go:"GO:0051117"(ATPase binding)|go:"GO:0060478"(acrosomal vesicle exocytosis)|go:"GO:0061670"(evoked neurotransmitter secretion)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0097091"(synaptic vesicle clustering)|go:"GO:0098993"(anchored component of synaptic vesicle membrane)|go:"GO:1903307"(positive regulation of regulated secretory pathway)|go:"GO:1905684"(regulation of plasma membrane repair)|go:"GO:2000300"(regulation of synaptic vesicle exocytosis)|interpro:IPR001806(Ras GTPase)|interpro:IPR005225(Small GTP-binding protein)|interpro:IPR027417|interpro:IPR037872|mint:P63012|rcsb pdb:1ZBD|rcsb pdb:3RAB|reactome:R-RNO-181429|reactome:R-RNO-181430|reactome:R-RNO-210500|reactome:R-RNO-212676|reactome:R-RNO-264642|reactome:R-RNO-6798695|reactome:R-RNO-8873719|reactome:R-RNO-8876198|reactome:R-RNO-888590|go:"GO:0051602"(response to electrical stimulus)|rgd:3528|refseq:NP_037150.2	-	-	-	figure legend:st1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10116(rat-brain-cortex)|taxid:10116(Rattus norvegicus brain cortex)	-	2020/10/30	2020/10/30	rogid:DtE+ZXAZKdCMvUW5K+jXQ5bH07M10116	rogid:Skrsn0x0LP/jAuOk1LQ4ataeiDA10116	rigid:3wclwrjZRvafcOruQOYnegkn54c	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q5XIE8	uniprotkb:P63319	intact:EBI-15348306|ensembl:ENSRNOP00000023037	intact:EBI-12598030|ensembl:ENSRNOP00000071203|uniprotkb:P05697|uniprotkb:Q5FWS3	psi-mi:itm2b_rat(display_long)|uniprotkb:Itm2b(gene name)|psi-mi:Itm2b(display_short)|uniprotkb:Immature BRI2(gene name synonym)|uniprotkb:Transmembrane protein BRI(gene name synonym)	psi-mi:kpcg_rat(display_long)|uniprotkb:Prkcg(gene name)|psi-mi:Prkcg(display_short)|uniprotkb:Pkcc(gene name synonym)|uniprotkb:Pkcg(gene name synonym)|uniprotkb:Prkcc(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Martins et al. (2018)	imex:IM-28469|pubmed:29476059	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26439741|imex:IM-28469-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSRNOG00000016271(gene)|ensembl:ENSRNOT00000023037(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001540"(amyloid-beta binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0010008"(endosome membrane)|go:"GO:0030660"(Golgi-associated vesicle membrane)|go:"GO:0031301"(integral component of organelle membrane)|go:"GO:0042985"(negative regulation of amyloid precursor protein biosynthetic process)|interpro:IPR007084(BRICHOS)|interpro:IPR040145|mint:Q5XIE8|refseq:NP_001006964.1|rgd:620727	ensembl:ENSRNOG00000054371(gene)|ensembl:ENSRNOT00000080032(transcript)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0004697"(protein kinase C activity)|go:"GO:0004698"(calcium-dependent protein kinase C activity)|go:"GO:0004712"(protein serine/threonine/tyrosine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0007268"(chemical synaptic transmission)|go:"GO:0007611"(learning or memory)|go:"GO:0007635"(chemosensory behavior)|go:"GO:0008270"(zinc ion binding)|go:"GO:0009636"(response to toxic substance)|go:"GO:0014069"(postsynaptic density)|go:"GO:0016020"(membrane)|go:"GO:0016310"(phosphorylation)|go:"GO:0018105"(peptidyl-serine phosphorylation)|go:"GO:0030425"(dendrite)|go:"GO:0031397"(negative regulation of protein ubiquitination)|go:"GO:0032095"(regulation of response to food)|go:"GO:0032425"(positive regulation of mismatch repair)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0042177"(negative regulation of protein catabolic process)|go:"GO:0042752"(regulation of circadian rhythm)|go:"GO:0043005"(neuron projection)|go:"GO:0043278"(response to morphine)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0044305"(calyx of Held)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0048265"(response to pain)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0048511"(rhythmic process)|go:"GO:0050764"(regulation of phagocytosis)|go:"GO:0060291"(long-term synaptic potentiation)|go:"GO:0060384"(innervation)|go:"GO:0097060"(synaptic membrane)|go:"GO:0099171"(presynaptic modulation of chemical synaptic transmission)|go:"GO:0099523"(presynaptic cytosol)|go:"GO:0099524"(postsynaptic cytosol)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:1901799"(negative regulation of proteasomal protein catabolic process)|go:"GO:1990911"(response to psychosocial stress)|go:"GO:2000300"(regulation of synaptic vesicle exocytosis)|interpro:IPR000008(C2 calcium-dependent membrane targeting)|interpro:IPR000719(Protein kinase, core)|interpro:IPR000961(Protein kinase, C-terminal)|interpro:IPR002219(Protein kinase C, phorbol ester/diacylglycerol binding)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR014375(Protein kinase C, alpha/beta/gamma types)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR017892|interpro:IPR020454|interpro:IPR035892|mint:P63319|rcsb pdb:1TBN|rcsb pdb:1TBO|reactome:R-RNO-111933|reactome:R-RNO-114516|reactome:R-RNO-416993|reactome:R-RNO-5099900|reactome:R-RNO-76005|rgd:3397|refseq:NP_036760.1	-	-	-	figure legend:st1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10116(rat-brain-cortex)|taxid:10116(Rattus norvegicus brain cortex)	-	2020/10/30	2020/10/30	rogid:DtE+ZXAZKdCMvUW5K+jXQ5bH07M10116	rogid:t4ukCPPAnYUtHCH1hnQE+uiyfEM10116	rigid:3wclwrjZRvafcOruQOYnegkn54c	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q5XIE8	uniprotkb:Q5XIH7	intact:EBI-15348306|ensembl:ENSRNOP00000023037	intact:EBI-918041|uniprotkb:P70629|uniprotkb:P70630|ensembl:ENSRNOP00000017472	psi-mi:itm2b_rat(display_long)|uniprotkb:Itm2b(gene name)|psi-mi:Itm2b(display_short)|uniprotkb:Immature BRI2(gene name synonym)|uniprotkb:Transmembrane protein BRI(gene name synonym)	psi-mi:phb2_rat(display_long)|uniprotkb:B-cell receptor-associated protein BAP37(gene name synonym)|uniprotkb:Phb2(gene name)|psi-mi:Phb2(display_short)|uniprotkb:Bcap37(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Martins et al. (2018)	imex:IM-28469|pubmed:29476059	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26439741|imex:IM-28469-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSRNOG00000016271(gene)|ensembl:ENSRNOT00000023037(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001540"(amyloid-beta binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0010008"(endosome membrane)|go:"GO:0030660"(Golgi-associated vesicle membrane)|go:"GO:0031301"(integral component of organelle membrane)|go:"GO:0042985"(negative regulation of amyloid precursor protein biosynthetic process)|interpro:IPR007084(BRICHOS)|interpro:IPR040145|mint:Q5XIE8|refseq:NP_001006964.1|rgd:620727	rgd:620203|refseq:NP_001013053.1|ensembl:ENSRNOG00000012999(gene)|ensembl:ENSRNOT00000017472(transcript)|go:"GO:0000423"(mitophagy)|go:"GO:0002639"(positive regulation of immunoglobulin production)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005886"(plasma membrane)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0007005"(mitochondrion organization)|go:"GO:0007062"(sister chromatid cohesion)|go:"GO:0007202"(activation of phospholipase C activity)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0009611"(response to wounding)|go:"GO:0009986"(cell surface)|go:"GO:0016363"(nuclear matrix)|go:"GO:0016477"(cell migration)|go:"GO:0023035"(CD40 signaling pathway)|go:"GO:0031536"(positive regulation of exit from mitosis)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033147"(negative regulation of intracellular estrogen receptor signaling pathway)|go:"GO:0033218"(amide binding)|go:"GO:0033600"(negative regulation of mammary gland epithelial cell proliferation)|go:"GO:0035632"(mitochondrial prohibitin complex)|go:"GO:0039520"(induction by virus of host autophagy)|go:"GO:0039529"(RIG-I signaling pathway)|go:"GO:0042113"(B cell activation)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043433"(negative regulation of DNA-binding transcription factor activity)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0046625"(sphingolipid binding)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0047485"(protein N-terminus binding)|go:"GO:0048786"(presynaptic active zone)|go:"GO:0050821"(protein stabilization)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0060744"(mammary gland branching involved in thelarche)|go:"GO:0060749"(mammary gland alveolus development)|go:"GO:0060762"(regulation of branching involved in mammary gland duct morphogenesis)|go:"GO:0070374"(positive regulation of ERK1 and ERK2 cascade)|go:"GO:0071300"(cellular response to retinoic acid)|go:"GO:0071456"(cellular response to hypoxia)|go:"GO:0071944"(cell periphery)|go:"GO:0098800"(inner mitochondrial membrane protein complex)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0098982"(GABA-ergic synapse)|go:"GO:0140374"(antiviral innate immune response)|go:"GO:1900208"(regulation of cardiolipin metabolic process)|go:"GO:1901224"(positive regulation of NIK/NF-kappaB signaling)|go:"GO:1902808"(positive regulation of cell cycle G1/S phase transition)|go:"GO:1904959"(regulation of cytochrome-c oxidase activity)|go:"GO:1990051"(activation of protein kinase C activity)|interpro:IPR000163(Prohibitin)|interpro:IPR001107(Band 7 protein)|interpro:IPR036013|mint:Q5XIH7|reactome:R-RNO-8949664|go:"GO:0014069"(postsynaptic density)	-	-	-	figure legend:st1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10116(rat-brain-cortex)|taxid:10116(Rattus norvegicus brain cortex)	-	2020/10/30	2020/10/30	rogid:DtE+ZXAZKdCMvUW5K+jXQ5bH07M10116	rogid:VjRorTWSSei7yX+hNlgLqK2S49810116	rigid:3wclwrjZRvafcOruQOYnegkn54c	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q5XIE8	uniprotkb:P67779	intact:EBI-15348306|ensembl:ENSRNOP00000023037	intact:EBI-298513|uniprotkb:P24142|uniprotkb:Q4V8M6|ensembl:ENSRNOP00000066502	psi-mi:itm2b_rat(display_long)|uniprotkb:Itm2b(gene name)|psi-mi:Itm2b(display_short)|uniprotkb:Immature BRI2(gene name synonym)|uniprotkb:Transmembrane protein BRI(gene name synonym)	psi-mi:phb_rat(display_long)|uniprotkb:Phb(gene name)|psi-mi:Phb(display_short)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Martins et al. (2018)	imex:IM-28469|pubmed:29476059	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26439741|imex:IM-28469-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSRNOG00000016271(gene)|ensembl:ENSRNOT00000023037(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001540"(amyloid-beta binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0010008"(endosome membrane)|go:"GO:0030660"(Golgi-associated vesicle membrane)|go:"GO:0031301"(integral component of organelle membrane)|go:"GO:0042985"(negative regulation of amyloid precursor protein biosynthetic process)|interpro:IPR007084(BRICHOS)|interpro:IPR040145|mint:Q5XIE8|refseq:NP_001006964.1|rgd:620727	go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005737"(cytoplasm)|go:"GO:0005769"(early endosome)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0007005"(mitochondrion organization)|go:"GO:0007202"(activation of phospholipase C activity)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0009986"(cell surface)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010942"(positive regulation of cell death)|go:"GO:0010944"(negative regulation of transcription by competitive promoter binding)|go:"GO:0014069"(postsynaptic density)|go:"GO:0016575"(histone deacetylation)|go:"GO:0019899"(enzyme binding)|go:"GO:0023035"(CD40 signaling pathway)|go:"GO:0030061"(mitochondrial crista)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0031100"(animal organ regeneration)|go:"GO:0031315"(extrinsic component of mitochondrial outer membrane)|go:"GO:0031871"(proteinase activated receptor binding)|go:"GO:0032740"(positive regulation of interleukin-17 production)|go:"GO:0034097"(response to cytokine)|go:"GO:0035632"(mitochondrial prohibitin complex)|go:"GO:0035902"(response to immobilization stress)|go:"GO:0039529"(RIG-I signaling pathway)|go:"GO:0042113"(B cell activation)|go:"GO:0042177"(negative regulation of protein catabolic process)|go:"GO:0042493"|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043434"(response to peptide hormone)|go:"GO:0044830"(modulation by host of viral RNA genome replication)|go:"GO:0045471"(response to ethanol)|go:"GO:0045745"(positive regulation of G protein-coupled receptor signaling pathway)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045917"(positive regulation of complement activation)|go:"GO:0046718"(viral entry into host cell)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0048661"(positive regulation of smooth muscle cell proliferation)|go:"GO:0050821"(protein stabilization)|go:"GO:0050847"(progesterone receptor signaling pathway)|go:"GO:0051897"(positive regulation of protein kinase B signaling)|go:"GO:0060766"(negative regulation of androgen receptor signaling pathway)|go:"GO:0070373"(negative regulation of ERK1 and ERK2 cascade)|go:"GO:0070374"(positive regulation of ERK1 and ERK2 cascade)|go:"GO:0071354"(cellular response to interleukin-6)|go:"GO:0071897"(DNA biosynthetic process)|go:"GO:0072538"(T-helper 17 type immune response)|go:"GO:0098891"(extrinsic component of presynaptic active zone membrane)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0042826"(histone deacetylase binding)|ensembl:ENSRNOG00000046799(gene)|ensembl:ENSRNOT00000075733(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0001541"(ovarian follicle development)|go:"GO:0001552"(ovarian follicle atresia)|go:"GO:0001850"(complement component C3a binding)|go:"GO:0001851"(complement component C3b binding)|go:"GO:0002639"(positive regulation of immunoglobulin production)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0140374"(antiviral innate immune response)|go:"GO:1901224"(positive regulation of NIK/NF-kappaB signaling)|go:"GO:1990051"(activation of protein kinase C activity)|go:"GO:2000323"(negative regulation of glucocorticoid receptor signaling pathway)|interpro:IPR000163(Prohibitin)|interpro:IPR001107(Band 7 protein)|go:"GO:0098982"(GABA-ergic synapse)|interpro:IPR036013|mint:P67779|reactome:R-RNO-5673000|reactome:R-RNO-8949664|rgd:3322|refseq:NP_114039.1	-	-	-	figure legend:st1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10116(rat-brain-cortex)|taxid:10116(Rattus norvegicus brain cortex)	-	2020/10/30	2020/10/30	rogid:DtE+ZXAZKdCMvUW5K+jXQ5bH07M10116	rogid:eUStcZ9Mu7+7MHr/GJXFwwJY/Fc10116	rigid:3wclwrjZRvafcOruQOYnegkn54c	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q5XIE8	uniprotkb:P19527	intact:EBI-15348306|ensembl:ENSRNOP00000023037	intact:EBI-446360|uniprotkb:Q63367|ensembl:ENSRNOP00000018599	psi-mi:itm2b_rat(display_long)|uniprotkb:Itm2b(gene name)|psi-mi:Itm2b(display_short)|uniprotkb:Immature BRI2(gene name synonym)|uniprotkb:Transmembrane protein BRI(gene name synonym)	psi-mi:nfl_rat(display_long)|uniprotkb:Neurofilament triplet L protein(gene name synonym)|uniprotkb:68 kDa neurofilament protein(gene name synonym)|uniprotkb:Nefl(gene name)|psi-mi:Nefl(display_short)|uniprotkb:Nf68(gene name synonym)|uniprotkb:Nfl(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Martins et al. (2018)	imex:IM-28469|pubmed:29476059	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26439741|imex:IM-28469-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSRNOG00000016271(gene)|ensembl:ENSRNOT00000023037(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001540"(amyloid-beta binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0010008"(endosome membrane)|go:"GO:0030660"(Golgi-associated vesicle membrane)|go:"GO:0031301"(integral component of organelle membrane)|go:"GO:0042985"(negative regulation of amyloid precursor protein biosynthetic process)|interpro:IPR007084(BRICHOS)|interpro:IPR040145|mint:Q5XIE8|refseq:NP_001006964.1|rgd:620727	rgd:621458|refseq:NP_113971.1|dip:DIP-1N|ensembl:ENSRNOG00000013658(gene)|ensembl:ENSRNOT00000018599(transcript)|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0005200"(structural constituent of cytoskeleton)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005882"(intermediate filament)|go:"GO:0005883"(neurofilament)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008089"(anterograde axonal transport)|go:"GO:0008090"(retrograde axonal transport)|go:"GO:0009636"(response to toxic substance)|go:"GO:0010033"(response to organic substance)|go:"GO:0014012"(peripheral nervous system axon regeneration)|go:"GO:0019896"(axonal transport of mitochondrion)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0021510"(spinal cord development)|go:"GO:0021766"(hippocampus development)|go:"GO:0021987"(cerebral cortex development)|go:"GO:0030424"(axon)|go:"GO:0030426"(growth cone)|go:"GO:0030674"(protein-macromolecule adaptor activity)|go:"GO:0031133"(regulation of axon diameter)|go:"GO:0031594"(neuromuscular junction)|go:"GO:0033693"(neurofilament bundle assembly)|go:"GO:0040011"(locomotion)|go:"GO:0042802"(identical protein binding)|go:"GO:0043005"(neuron projection)|go:"GO:0043274"(phospholipase binding)|go:"GO:0043434"(response to peptide hormone)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045105"(intermediate filament polymerization or depolymerization)|go:"GO:0045109"(intermediate filament organization)|go:"GO:0045110"(intermediate filament bundle assembly)|go:"GO:0048812"(neuron projection morphogenesis)|go:"GO:0050772"(positive regulation of axonogenesis)|go:"GO:0050885"(neuromuscular process controlling balance)|go:"GO:0051258"(protein polymerization)|go:"GO:0051412"(response to corticosterone)|go:"GO:0060052"(neurofilament cytoskeleton organization)|go:"GO:0060074"(synapse maturation)|go:"GO:0098685"(Schaffer collateral - CA1 synapse)|go:"GO:0098981"(cholinergic synapse)|go:"GO:0099182"(presynaptic intermediate filament cytoskeleton)|go:"GO:0099184"(structural constituent of postsynaptic intermediate filament cytoskeleton)|go:"GO:1903935"(response to sodium arsenite)|go:"GO:1903937"(response to acrylamide)|go:"GO:0099160"(postsynaptic intermediate filament cytoskeleton)|go:"GO:1904115"(axon cytoplasm)|interpro:IPR006821(Intermediate filament, DNA-binding region)|interpro:IPR018039|interpro:IPR027692|interpro:IPR039008|mint:P19527|reactome:R-RNO-438066|reactome:R-RNO-5673001	-	-	-	figure legend:st1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10116(rat-brain-cortex)|taxid:10116(Rattus norvegicus brain cortex)	-	2020/10/30	2020/10/30	rogid:DtE+ZXAZKdCMvUW5K+jXQ5bH07M10116	rogid:j/u8VG9hdvpMSY4/bU7l4hxX41Q10116	rigid:3wclwrjZRvafcOruQOYnegkn54c	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q5XIE8	uniprotkb:P16884	intact:EBI-15348306|ensembl:ENSRNOP00000023037	intact:EBI-446344|uniprotkb:O35482|uniprotkb:Q540Z7|uniprotkb:Q63368	psi-mi:itm2b_rat(display_long)|uniprotkb:Itm2b(gene name)|psi-mi:Itm2b(display_short)|uniprotkb:Immature BRI2(gene name synonym)|uniprotkb:Transmembrane protein BRI(gene name synonym)	psi-mi:nfh_rat(display_long)|uniprotkb:Neurofilament triplet H protein(gene name synonym)|uniprotkb:200 kDa neurofilament protein(gene name synonym)|uniprotkb:Nefh(gene name)|psi-mi:Nefh(display_short)|uniprotkb:Nfh(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Martins et al. (2018)	imex:IM-28469|pubmed:29476059	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26439741|imex:IM-28469-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSRNOG00000016271(gene)|ensembl:ENSRNOT00000023037(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001540"(amyloid-beta binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0010008"(endosome membrane)|go:"GO:0030660"(Golgi-associated vesicle membrane)|go:"GO:0031301"(integral component of organelle membrane)|go:"GO:0042985"(negative regulation of amyloid precursor protein biosynthetic process)|interpro:IPR007084(BRICHOS)|interpro:IPR040145|mint:Q5XIE8|refseq:NP_001006964.1|rgd:620727	rgd:3159|dip:DIP-105N|mint:P16884|go:"GO:0007420"(brain development)|go:"GO:0014069"(postsynaptic density)|go:"GO:0015643"(toxic substance binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0021510"(spinal cord development)|go:"GO:0021766"(hippocampus development)|go:"GO:0021987"(cerebral cortex development)|go:"GO:0030424"(axon)|go:"GO:0030674"(protein-macromolecule adaptor activity)|go:"GO:0031103"(axon regeneration)|go:"GO:0031175"(neuron projection development)|go:"GO:0033693"(neurofilament bundle assembly)|go:"GO:0034599"(cellular response to oxidative stress)|go:"GO:0042220"(response to cocaine)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043204"(perikaryon)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045104"(intermediate filament cytoskeleton organization)|go:"GO:0045110"(intermediate filament bundle assembly)|go:"GO:0048936"(peripheral nervous system neuron axonogenesis)|go:"GO:0060052"(neurofilament cytoskeleton organization)|go:"GO:0061564"(axon development)|go:"GO:0071392"(cellular response to estradiol stimulus)|go:"GO:0071447"(cellular response to hydroperoxide)|go:"GO:0097418"(neurofibrillary tangle)|go:"GO:0097440"(apical dendrite)|go:"GO:0098685"(Schaffer collateral - CA1 synapse)|go:"GO:0099160"(postsynaptic intermediate filament cytoskeleton)|go:"GO:0099184"(structural constituent of postsynaptic intermediate filament cytoskeleton)|go:"GO:0150017"(basal proximal dendrite)|go:"GO:1902513"(regulation of organelle transport along microtubule)|go:"GO:1903935"(response to sodium arsenite)|go:"GO:1903937"(response to acrylamide)|go:"GO:1990830"(cellular response to leukemia inhibitory factor)|interpro:IPR010790(Protein of unknown function DUF1388)|interpro:IPR018039|interpro:IPR033183|interpro:IPR039008|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0001552"(ovarian follicle atresia)|go:"GO:0005200"(structural constituent of cytoskeleton)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005882"(intermediate filament)|go:"GO:0005883"(neurofilament)	-	-	-	figure legend:st1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10116(rat-brain-cortex)|taxid:10116(Rattus norvegicus brain cortex)	-	2020/10/30	2020/10/30	rogid:DtE+ZXAZKdCMvUW5K+jXQ5bH07M10116	rogid:ouBvM47wkf3tA9ZWmjX5jObpZtE10116	rigid:3wclwrjZRvafcOruQOYnegkn54c	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q5XIE8	uniprotkb:P97685	intact:EBI-15348306|ensembl:ENSRNOP00000023037	intact:EBI-26437804|ensembl:ENSRNOP00000057594|uniprotkb:P97684|uniprotkb:Q91Z60	psi-mi:itm2b_rat(display_long)|uniprotkb:Itm2b(gene name)|psi-mi:Itm2b(display_short)|uniprotkb:Immature BRI2(gene name synonym)|uniprotkb:Transmembrane protein BRI(gene name synonym)	psi-mi:nfasc_rat(display_long)|uniprotkb:Nfasc(gene name)|psi-mi:Nfasc(display_short)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Martins et al. (2018)	imex:IM-28469|pubmed:29476059	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26439741|imex:IM-28469-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSRNOG00000016271(gene)|ensembl:ENSRNOT00000023037(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001540"(amyloid-beta binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0010008"(endosome membrane)|go:"GO:0030660"(Golgi-associated vesicle membrane)|go:"GO:0031301"(integral component of organelle membrane)|go:"GO:0042985"(negative regulation of amyloid precursor protein biosynthetic process)|interpro:IPR007084(BRICHOS)|interpro:IPR040145|mint:Q5XIE8|refseq:NP_001006964.1|rgd:620727	go:"GO:0019904"(protein domain specific binding)|ensembl:ENSRNOG00000030515(gene)|go:"GO:0030424"(axon)|ensembl:ENSRNOT00000060871(transcript)|go:"GO:0002175"(protein localization to paranode region of axon)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0005918"(septate junction)|go:"GO:0007411"(axon guidance)|go:"GO:0007422"(peripheral nervous system development)|go:"GO:0019226"(transmission of nerve impulse)|go:"GO:0030425"(dendrite)|go:"GO:0030913"(paranodal junction assembly)|go:"GO:0033010"(paranodal junction)|go:"GO:0033268"(node of Ranvier)|go:"GO:0033270"(paranode region of axon)|go:"GO:0042552"(myelination)|go:"GO:0043194"(axon initial segment)|go:"GO:0045162"(clustering of voltage-gated sodium channels)|go:"GO:0050808"(synapse organization)|go:"GO:0071205"(protein localization to juxtaparanode region of axon)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0086080"(protein binding involved in heterotypic cell-cell adhesion)|go:"GO:0097454"(Schwann cell microvillus)|interpro:IPR003598(Immunoglobulin subtype 2)|interpro:IPR003599(Immunoglobulin subtype)|interpro:IPR003961(Fibronectin, type III)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR013098(Immunoglobulin I-set)|interpro:IPR013151(Immunoglobulin)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR026965|interpro:IPR026966|interpro:IPR036116|interpro:IPR036179|interpro:IPR043204|mint:P97685|reactome:R-RNO-447043|reactome:R-RNO-6798695|refseq:NP_001153785.1|refseq:NP_001153786.1|refseq:NP_446361.1|rgd:620911	-	-	-	figure legend:st1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10116(rat-brain-cortex)|taxid:10116(Rattus norvegicus brain cortex)	-	2020/10/30	2020/10/30	rogid:DtE+ZXAZKdCMvUW5K+jXQ5bH07M10116	rogid:HzCYcx8+shkIPZAc7h3T3dYDxDc10116	rigid:3wclwrjZRvafcOruQOYnegkn54c	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q5XIE8	uniprotkb:P55067	intact:EBI-15348306|ensembl:ENSRNOP00000023037	intact:EBI-26437766	psi-mi:itm2b_rat(display_long)|uniprotkb:Itm2b(gene name)|psi-mi:Itm2b(display_short)|uniprotkb:Immature BRI2(gene name synonym)|uniprotkb:Transmembrane protein BRI(gene name synonym)	psi-mi:ncan_rat(display_long)|uniprotkb:Ncan(gene name)|psi-mi:Ncan(display_short)|uniprotkb:Cspg3(gene name synonym)|uniprotkb:245 kDa early postnatal core glycoprotein(gene name synonym)|uniprotkb:Chondroitin sulfate proteoglycan 3(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Martins et al. (2018)	imex:IM-28469|pubmed:29476059	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26439741|imex:IM-28469-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSRNOG00000016271(gene)|ensembl:ENSRNOT00000023037(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001540"(amyloid-beta binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0010008"(endosome membrane)|go:"GO:0030660"(Golgi-associated vesicle membrane)|go:"GO:0031301"(integral component of organelle membrane)|go:"GO:0042985"(negative regulation of amyloid precursor protein biosynthetic process)|interpro:IPR007084(BRICHOS)|interpro:IPR040145|mint:Q5XIE8|refseq:NP_001006964.1|rgd:620727	go:"GO:0001501"(skeletal system development)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005540"(hyaluronic acid binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005886"(plasma membrane)|go:"GO:0007155"(cell adhesion)|go:"GO:0007417"(central nervous system development)|go:"GO:0030246"(carbohydrate binding)|go:"GO:0031012"(extracellular matrix)|go:"GO:0045202"(synapse)|go:"GO:0051823"(regulation of synapse structural plasticity)|go:"GO:0072534"(perineuronal net)|reactome:R-RNO-1971475|reactome:R-RNO-2022870|reactome:R-RNO-2022923|reactome:R-RNO-2024101|reactome:R-RNO-3000178|mint:P55067|interpro:IPR001304(C-type lectin)|interpro:IPR016186(C-type lectin-like)|interpro:IPR018378|interpro:IPR016187(C-type lectin fold)|interpro:IPR001881(EGF-like calcium-binding)|interpro:IPR000742(EGF-like, type 3)|interpro:IPR000152(Aspartic acid and asparagine hydroxylation site)|interpro:IPR018097|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR036179|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR003599(Immunoglobulin subtype)|interpro:IPR013106(Immunoglobulin V-set)|interpro:IPR000538(Link)|interpro:IPR035976|interpro:IPR000436(Sushi/SCR/CCP)|rgd:619941	-	-	-	figure legend:st1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10116(rat-brain-cortex)|taxid:10116(Rattus norvegicus brain cortex)	-	2020/10/30	2020/10/30	rogid:DtE+ZXAZKdCMvUW5K+jXQ5bH07M10116	rogid:2/ICeFV747SqaUpp9GStWXPuhcc10116	rigid:3wclwrjZRvafcOruQOYnegkn54c	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q5XIE8	uniprotkb:Q64119	intact:EBI-15348306|ensembl:ENSRNOP00000023037	intact:EBI-26437750	psi-mi:itm2b_rat(display_long)|uniprotkb:Itm2b(gene name)|psi-mi:Itm2b(display_short)|uniprotkb:Immature BRI2(gene name synonym)|uniprotkb:Transmembrane protein BRI(gene name synonym)	psi-mi:myl6_rat(display_long)|uniprotkb:Myl6(gene name)|psi-mi:Myl6(display_short)|uniprotkb:17 kDa myosin light chain(gene name synonym)|uniprotkb:Myosin light chain 3(gene name synonym)|uniprotkb:Myosin light chain alkali 3(gene name synonym)|uniprotkb:Smooth muscle and nonmuscle myosin light chain alkali 6(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Martins et al. (2018)	imex:IM-28469|pubmed:29476059	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26439741|imex:IM-28469-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSRNOG00000016271(gene)|ensembl:ENSRNOT00000023037(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001540"(amyloid-beta binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0010008"(endosome membrane)|go:"GO:0030660"(Golgi-associated vesicle membrane)|go:"GO:0031301"(integral component of organelle membrane)|go:"GO:0042985"(negative regulation of amyloid precursor protein biosynthetic process)|interpro:IPR007084(BRICHOS)|interpro:IPR040145|mint:Q5XIE8|refseq:NP_001006964.1|rgd:620727	go:"GO:0000146"(microfilament motor activity)|go:"GO:0003774"(cytoskeletal motor activity)|go:"GO:0005509"(calcium ion binding)|go:"GO:0006936"(muscle contraction)|go:"GO:0007519"(skeletal muscle tissue development)|go:"GO:0008307"(structural constituent of muscle)|go:"GO:0016459"(myosin complex)|go:"GO:0016461"(unconventional myosin complex)|go:"GO:0030049"(muscle filament sliding)|mint:Q64119|refseq:NP_001094453.1|interpro:IPR011992(EF-Hand type)|interpro:IPR002048(Calcium-binding EF-hand)|rgd:1305620	-	-	-	figure legend:st1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10116(rat-brain-cortex)|taxid:10116(Rattus norvegicus brain cortex)	-	2020/10/30	2020/10/30	rogid:DtE+ZXAZKdCMvUW5K+jXQ5bH07M10116	rogid:7L1ZyEG5CDK89dn56Tvy1TZlSPc10116	rigid:3wclwrjZRvafcOruQOYnegkn54c	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q5XIE8	uniprotkb:Q63560	intact:EBI-15348306|ensembl:ENSRNOP00000023037	intact:EBI-1638469|uniprotkb:O88748|uniprotkb:Q6AYX8	psi-mi:itm2b_rat(display_long)|uniprotkb:Itm2b(gene name)|psi-mi:Itm2b(display_short)|uniprotkb:Immature BRI2(gene name synonym)|uniprotkb:Transmembrane protein BRI(gene name synonym)	psi-mi:map6_rat(display_long)|uniprotkb:Map6(gene name)|psi-mi:Map6(display_short)|uniprotkb:Mtap6(gene name synonym)|uniprotkb:Stable tubule-only polypeptide(gene name synonym)|uniprotkb:145-kDa STOP(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Martins et al. (2018)	imex:IM-28469|pubmed:29476059	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26439741|imex:IM-28469-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSRNOG00000016271(gene)|ensembl:ENSRNOT00000023037(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001540"(amyloid-beta binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0010008"(endosome membrane)|go:"GO:0030660"(Golgi-associated vesicle membrane)|go:"GO:0031301"(integral component of organelle membrane)|go:"GO:0042985"(negative regulation of amyloid precursor protein biosynthetic process)|interpro:IPR007084(BRICHOS)|interpro:IPR040145|mint:Q5XIE8|refseq:NP_001006964.1|rgd:620727	interpro:IPR007882(STOP)|rgd:61804|refseq:NP_058900.1|mint:Q63560|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005798"(Golgi-associated vesicle)|go:"GO:0005801"(cis-Golgi network)|go:"GO:0005874"(microtubule)|go:"GO:0008017"(microtubule binding)|go:"GO:0019896"(axonal transport of mitochondrion)|go:"GO:0030424"(axon)|go:"GO:0030425"(dendrite)|go:"GO:0030658"(transport vesicle membrane)|go:"GO:0030705"(cytoskeleton-dependent intracellular transport)|go:"GO:0032418"(lysosome localization)|go:"GO:0043005"(neuron projection)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0048813"(dendrite morphogenesis)|go:"GO:0050772"(positive regulation of axonogenesis)|go:"GO:0070507"(regulation of microtubule cytoskeleton organization)|go:"GO:0099503"(secretory vesicle)|go:"GO:1904115"(axon cytoplasm)	-	-	-	figure legend:st1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10116(rat-brain-cortex)|taxid:10116(Rattus norvegicus brain cortex)	-	2020/10/30	2020/10/30	rogid:DtE+ZXAZKdCMvUW5K+jXQ5bH07M10116	rogid:lWnLN3HrXruyxTIYdSN5wtDmea010116	rigid:3wclwrjZRvafcOruQOYnegkn54c	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q5XIE8	uniprotkb:P15205	intact:EBI-15348306|ensembl:ENSRNOP00000023037	intact:EBI-349666|uniprotkb:Q62958|uniprotkb:Q9ER21|uniprotkb:Q9QW92|ensembl:ENSRNOP00000023460|uniprotkb:B0BNK3|uniprotkb:F1LRL9	psi-mi:itm2b_rat(display_long)|uniprotkb:Itm2b(gene name)|psi-mi:Itm2b(display_short)|uniprotkb:Immature BRI2(gene name synonym)|uniprotkb:Transmembrane protein BRI(gene name synonym)	psi-mi:map1b_rat(display_long)|uniprotkb:Map1b(gene name)|psi-mi:Map1b(display_short)|uniprotkb:Neuraxin(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Martins et al. (2018)	imex:IM-28469|pubmed:29476059	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26439741|imex:IM-28469-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSRNOG00000016271(gene)|ensembl:ENSRNOT00000023037(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001540"(amyloid-beta binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0010008"(endosome membrane)|go:"GO:0030660"(Golgi-associated vesicle membrane)|go:"GO:0031301"(integral component of organelle membrane)|go:"GO:0042985"(negative regulation of amyloid precursor protein biosynthetic process)|interpro:IPR007084(BRICHOS)|interpro:IPR040145|mint:Q5XIE8|refseq:NP_001006964.1|rgd:620727	rgd:3043|refseq:NP_062090.1|ensembl:ENSRNOG00000017428(gene)|ensembl:ENSRNOT00000023460(transcript)|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0001578"(microtubule bundle formation)|go:"GO:0001750"(photoreceptor outer segment)|go:"GO:0003779"(actin binding)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005874"(microtubule)|go:"GO:0005875"(microtubule associated complex)|go:"GO:0005886"(plasma membrane)|go:"GO:0007026"(negative regulation of microtubule depolymerization)|go:"GO:0007399"(nervous system development)|go:"GO:0007409"(axonogenesis)|go:"GO:0007416"(synapse assembly)|go:"GO:0008017"(microtubule binding)|go:"GO:0009611"(response to wounding)|go:"GO:0009612"(response to mechanical stimulus)|go:"GO:0009743"(response to carbohydrate)|go:"GO:0009987"(cellular process)|go:"GO:0010035"(response to inorganic substance)|go:"GO:0014012"(peripheral nervous system axon regeneration)|go:"GO:0014069"(postsynaptic density)|go:"GO:0016358"(dendrite development)|go:"GO:0017085"(response to insecticide)|go:"GO:0005543"(phospholipid binding)|go:"GO:0048675"(axon extension)|go:"GO:0048678"(response to axon injury)|go:"GO:0051915"(induction of synaptic plasticity by chemical substance)|go:"GO:0061162"(establishment of monopolar cell polarity)|go:"GO:0071363"(cellular response to growth factor stimulus)|go:"GO:0071375"(cellular response to peptide hormone stimulus)|go:"GO:0097440"(apical dendrite)|go:"GO:0097441"(basal dendrite)|go:"GO:0097457"(hippocampal mossy fiber)|interpro:IPR000102(Neuraxin/MAP1B repeat)|interpro:IPR026074|interpro:IPR027321|mint:P15205|go:"GO:0030424"(axon)|go:"GO:0030425"(dendrite)|go:"GO:0030426"(growth cone)|go:"GO:0031114"(regulation of microtubule depolymerization)|go:"GO:0021700"(developmental maturation)|go:"GO:0031116"(positive regulation of microtubule polymerization)|go:"GO:0031667"(response to nutrient levels)|go:"GO:0032355"(response to estradiol)|go:"GO:0032387"(negative regulation of intracellular transport)|go:"GO:0033189"(response to vitamin A)|go:"GO:0036477"(somatodendritic compartment)|go:"GO:0042493"|go:"GO:0043025"(neuronal cell body)|go:"GO:0043196"(varicosity)|go:"GO:0043197"(dendritic spine)|go:"GO:0043204"(perikaryon)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045202"(synapse)|go:"GO:0045666"(positive regulation of neuron differentiation)|go:"GO:0045773"(positive regulation of axon extension)|go:"GO:0047497"(mitochondrion transport along microtubule)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0048666"(neuron development)	-	-	-	figure legend:st1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10116(rat-brain-cortex)|taxid:10116(Rattus norvegicus brain cortex)	-	2020/10/30	2020/10/30	rogid:DtE+ZXAZKdCMvUW5K+jXQ5bH07M10116	rogid:ymryqrEfxWtJQiPb6jgYe8bzDX410116	rigid:3wclwrjZRvafcOruQOYnegkn54c	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q5XIE8	uniprotkb:Q3KR86	intact:EBI-15348306|ensembl:ENSRNOP00000023037	intact:EBI-16220282	psi-mi:itm2b_rat(display_long)|uniprotkb:Itm2b(gene name)|psi-mi:Itm2b(display_short)|uniprotkb:Immature BRI2(gene name synonym)|uniprotkb:Transmembrane protein BRI(gene name synonym)	psi-mi:mic60_rat(display_long)|uniprotkb:Immt(gene name)|psi-mi:Immt(display_short)|uniprotkb:Mic60(gene name synonym)|uniprotkb:Mitochondrial inner membrane protein(gene name synonym)|uniprotkb:Mitofilin(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Martins et al. (2018)	imex:IM-28469|pubmed:29476059	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26439741|imex:IM-28469-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSRNOG00000016271(gene)|ensembl:ENSRNOT00000023037(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001540"(amyloid-beta binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0010008"(endosome membrane)|go:"GO:0030660"(Golgi-associated vesicle membrane)|go:"GO:0031301"(integral component of organelle membrane)|go:"GO:0042985"(negative regulation of amyloid precursor protein biosynthetic process)|interpro:IPR007084(BRICHOS)|interpro:IPR040145|mint:Q5XIE8|refseq:NP_001006964.1|rgd:620727	go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005758"(mitochondrial intermembrane space)|go:"GO:0009409"(response to cold)|go:"GO:0042407"(cristae formation)|go:"GO:0051560"(mitochondrial calcium ion homeostasis)|go:"GO:0061617"(MICOS complex)|mint:Q3KR86|rgd:1310684|refseq:NP_001030100.1|interpro:IPR019133	-	-	-	figure legend:st1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10116(rat-brain-cortex)|taxid:10116(Rattus norvegicus brain cortex)	-	2020/10/30	2020/10/30	rogid:DtE+ZXAZKdCMvUW5K+jXQ5bH07M10116	rogid:8w7k7GqkoWnY0fLU70i0ItueVVI10116	rigid:3wclwrjZRvafcOruQOYnegkn54c	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q5XIE8	uniprotkb:Q2PQA9	intact:EBI-15348306|ensembl:ENSRNOP00000023037	intact:EBI-920191|uniprotkb:Q9WV65|ensembl:ENSRNOP00000023860	psi-mi:itm2b_rat(display_long)|uniprotkb:Itm2b(gene name)|psi-mi:Itm2b(display_short)|uniprotkb:Immature BRI2(gene name synonym)|uniprotkb:Transmembrane protein BRI(gene name synonym)	psi-mi:kinh_rat(display_long)|uniprotkb:Kif5b(gene name)|psi-mi:Kif5b(display_short)|uniprotkb:Ubiquitous kinesin heavy chain(gene name synonym)|uniprotkb:Conventional kinesin heavy chain(gene name synonym)|uniprotkb:Khc(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Martins et al. (2018)	imex:IM-28469|pubmed:29476059	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26439741|imex:IM-28469-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSRNOG00000016271(gene)|ensembl:ENSRNOT00000023037(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001540"(amyloid-beta binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0010008"(endosome membrane)|go:"GO:0030660"(Golgi-associated vesicle membrane)|go:"GO:0031301"(integral component of organelle membrane)|go:"GO:0042985"(negative regulation of amyloid precursor protein biosynthetic process)|interpro:IPR007084(BRICHOS)|interpro:IPR040145|mint:Q5XIE8|refseq:NP_001006964.1|rgd:620727	rgd:621559|refseq:NP_476550.1|refseq:XP_006254067.1|ensembl:ENSRNOG00000017466(gene)|ensembl:ENSRNOT00000023861(transcript)|go:"GO:0003777"(microtubule motor activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005829"(cytosol)|go:"GO:0005871"(kinesin complex)|go:"GO:0005874"(microtubule)|go:"GO:0007018"(microtubule-based movement)|go:"GO:0007028"(cytoplasm organization)|go:"GO:0007411"(axon guidance)|go:"GO:0007420"(brain development)|go:"GO:0008017"(microtubule binding)|go:"GO:0008432"(JUN kinase binding)|go:"GO:0008574"(plus-end-directed microtubule motor activity)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0021766"(hippocampus development)|go:"GO:0030139"(endocytic vesicle)|go:"GO:0030705"(cytoskeleton-dependent intracellular transport)|go:"GO:0031340"(positive regulation of vesicle fusion)|go:"GO:0031982"(vesicle)|go:"GO:0032230"(positive regulation of synaptic transmission, GABAergic)|go:"GO:0032418"(lysosome localization)|go:"GO:0032839"(dendrite cytoplasm)|go:"GO:0034451"(centriolar satellite)|go:"GO:0035253"(ciliary rootlet)|go:"GO:0035617"(stress granule disassembly)|go:"GO:0035774"(positive regulation of insulin secretion involved in cellular response to glucose stimulus)|go:"GO:0042267"(natural killer cell mediated cytotoxicity)|go:"GO:0042391"(regulation of membrane potential)|go:"GO:0042802"(identical protein binding)|go:"GO:0043005"(neuron projection)|go:"GO:0043227"(membrane-bounded organelle)|go:"GO:0043268"(positive regulation of potassium ion transport)|go:"GO:0044295"(axonal growth cone)|go:"GO:0045335"(phagocytic vesicle)|go:"GO:0047496"(vesicle transport along microtubule)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0048489"(synaptic vesicle transport)|go:"GO:0051642"(centrosome localization)|go:"GO:0071346"(cellular response to interferon-gamma)|go:"GO:0072383"(plus-end-directed vesicle transport along microtubule)|go:"GO:0090316"(positive regulation of intracellular protein transport)|go:"GO:0098971"(anterograde dendritic transport of neurotransmitter receptor complex)|go:"GO:0099609"(microtubule lateral binding)|go:"GO:0099641"(anterograde axonal protein transport)|go:"GO:1903078"(positive regulation of protein localization to plasma membrane)|go:"GO:1904115"(axon cytoplasm)|go:"GO:1905152"(positive regulation of voltage-gated sodium channel activity)|go:"GO:1990049"(retrograde neuronal dense core vesicle transport)|interpro:IPR001752(Kinesin, motor region)|interpro:IPR019821|interpro:IPR027417|interpro:IPR027640|interpro:IPR036961|mint:Q2PQA9|rcsb pdb:4ATX|reactome:R-RNO-2132295|reactome:R-RNO-5625970|reactome:R-RNO-6811434|reactome:R-RNO-983189|dip:DIP-37054N	-	-	-	figure legend:st1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10116(rat-brain-cortex)|taxid:10116(Rattus norvegicus brain cortex)	-	2020/10/30	2020/10/30	rogid:DtE+ZXAZKdCMvUW5K+jXQ5bH07M10116	rogid:OjHE/OLj2diwiW5HI0HFHEDkbjY10116	rigid:3wclwrjZRvafcOruQOYnegkn54c	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q5XIE8	uniprotkb:P37285	intact:EBI-15348306|ensembl:ENSRNOP00000023037	intact:EBI-917396|ensembl:ENSRNOP00000075931	psi-mi:itm2b_rat(display_long)|uniprotkb:Itm2b(gene name)|psi-mi:Itm2b(display_short)|uniprotkb:Immature BRI2(gene name synonym)|uniprotkb:Transmembrane protein BRI(gene name synonym)	psi-mi:klc1_rat(display_long)|uniprotkb:Klc1(gene name)|psi-mi:Klc1(display_short)|uniprotkb:Klc(gene name synonym)|uniprotkb:Kns2(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Martins et al. (2018)	imex:IM-28469|pubmed:29476059	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26439741|imex:IM-28469-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSRNOG00000016271(gene)|ensembl:ENSRNOT00000023037(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001540"(amyloid-beta binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0010008"(endosome membrane)|go:"GO:0030660"(Golgi-associated vesicle membrane)|go:"GO:0031301"(integral component of organelle membrane)|go:"GO:0042985"(negative regulation of amyloid precursor protein biosynthetic process)|interpro:IPR007084(BRICHOS)|interpro:IPR040145|mint:Q5XIE8|refseq:NP_001006964.1|rgd:620727	rgd:621411|refseq:NP_001075442.1|refseq:NP_001075443.1|dip:DIP-36927N|ensembl:ENSRNOG00000011572(gene)|ensembl:ENSRNOT00000092774(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005871"(kinesin complex)|go:"GO:0005874"(microtubule)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0008088"(axo-dendritic transport)|go:"GO:0015631"(tubulin binding)|go:"GO:0016020"(membrane)|go:"GO:0030424"(axon)|go:"GO:0030426"(growth cone)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0031982"(vesicle)|go:"GO:0035253"(ciliary rootlet)|go:"GO:0035418"(protein localization to synapse)|go:"GO:0035617"(stress granule disassembly)|go:"GO:0043005"(neuron projection)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043227"(membrane-bounded organelle)|interpro:IPR002151(Kinesin light chain)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR015792(Kinesin light chain repeat)|interpro:IPR019734|mint:P37285|reactome:R-RNO-2132295|reactome:R-RNO-5625970|reactome:R-RNO-6811434|reactome:R-RNO-983189	-	-	-	figure legend:st1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10116(rat-brain-cortex)|taxid:10116(Rattus norvegicus brain cortex)	-	2020/10/30	2020/10/30	rogid:DtE+ZXAZKdCMvUW5K+jXQ5bH07M10116	rogid:4o3poOHtmPnoLq/XTguA0Z1P14o10116	rigid:3wclwrjZRvafcOruQOYnegkn54c	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q5XIE8	uniprotkb:Q63617	intact:EBI-15348306|ensembl:ENSRNOP00000023037	intact:EBI-8761989	psi-mi:itm2b_rat(display_long)|uniprotkb:Itm2b(gene name)|psi-mi:Itm2b(display_short)|uniprotkb:Immature BRI2(gene name synonym)|uniprotkb:Transmembrane protein BRI(gene name synonym)	psi-mi:hyou1_rat(display_long)|uniprotkb:Hyou1(gene name)|psi-mi:Hyou1(display_short)|uniprotkb:Orp150(gene name synonym)|uniprotkb:150 kDa oxygen-regulated protein(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Martins et al. (2018)	imex:IM-28469|pubmed:29476059	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26439741|imex:IM-28469-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSRNOG00000016271(gene)|ensembl:ENSRNOT00000023037(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001540"(amyloid-beta binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0010008"(endosome membrane)|go:"GO:0030660"(Golgi-associated vesicle membrane)|go:"GO:0031301"(integral component of organelle membrane)|go:"GO:0042985"(negative regulation of amyloid precursor protein biosynthetic process)|interpro:IPR007084(BRICHOS)|interpro:IPR040145|mint:Q5XIE8|refseq:NP_001006964.1|rgd:620727	mint:Q63617|interpro:IPR018181|interpro:IPR013126(Heat shock protein 70)|refseq:NP_620222.2|rgd:621146|interpro:IPR029047|interpro:IPR029048|go:"GO:0001666"(response to hypoxia)|go:"GO:0002931"(response to ischemia)|go:"GO:0005524"(ATP binding)|go:"GO:0005788"(endoplasmic reticulum lumen)|go:"GO:0005790"(smooth endoplasmic reticulum)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0034663"(endoplasmic reticulum chaperone complex)|go:"GO:0034976"(response to endoplasmic reticulum stress)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0071456"(cellular response to hypoxia)|go:"GO:1903298"(negative regulation of hypoxia-induced intrinsic apoptotic signaling pathway)|go:"GO:1903382"(negative regulation of endoplasmic reticulum stress-induced neuron intrinsic apoptotic signaling pathway)|interpro:IPR043129	-	-	-	figure legend:st1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10116(rat-brain-cortex)|taxid:10116(Rattus norvegicus brain cortex)	-	2020/10/30	2020/10/30	rogid:DtE+ZXAZKdCMvUW5K+jXQ5bH07M10116	rogid:a64+yExj4exM2hN2NiQHoMi/Y4A10116	rigid:3wclwrjZRvafcOruQOYnegkn54c	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q5XIE8	uniprotkb:P62804	intact:EBI-15348306|ensembl:ENSRNOP00000023037	intact:EBI-16220020|ensembl:ENSRNOP00000039602|ensembl:ENSRNOP00000066622|ensembl:ENSRNOP00000066653|ensembl:ENSRNOP00000066695|ensembl:ENSRNOP00000067176|ensembl:ENSRNOP00000067502|ensembl:ENSRNOP00000067813|ensembl:ENSRNOP00000069989|ensembl:ENSRNOP00000071163|ensembl:ENSRNOP00000074659|ensembl:ENSRNOP00000074796|ensembl:ENSRNOP00000065233|uniprotkb:P02304|uniprotkb:P02305|uniprotkb:Q5BM23|uniprotkb:Q7M0E8	psi-mi:itm2b_rat(display_long)|uniprotkb:Itm2b(gene name)|psi-mi:Itm2b(display_short)|uniprotkb:Immature BRI2(gene name synonym)|uniprotkb:Transmembrane protein BRI(gene name synonym)	psi-mi:h4_rat(display_long)|uniprotkb:H4c2(gene name)|psi-mi:H4c2(display_short)|uniprotkb:H4f16(gene name)|psi-mi:H4f16(display_short)|uniprotkb:Hist4h4(gene name synonym)|uniprotkb:Hist1h4b(gene name synonym)|uniprotkb:Hist4(gene name synonym)|uniprotkb:Hist1h4m(gene name)|psi-mi:Hist1h4m(display_short)|uniprotkb:H4ft(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Martins et al. (2018)	imex:IM-28469|pubmed:29476059	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26439741|imex:IM-28469-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSRNOG00000016271(gene)|ensembl:ENSRNOT00000023037(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001540"(amyloid-beta binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0010008"(endosome membrane)|go:"GO:0030660"(Golgi-associated vesicle membrane)|go:"GO:0031301"(integral component of organelle membrane)|go:"GO:0042985"(negative regulation of amyloid precursor protein biosynthetic process)|interpro:IPR007084(BRICHOS)|interpro:IPR040145|mint:Q5XIE8|refseq:NP_001006964.1|rgd:620727	ensembl:ENSRNOG00000032224(gene)|ensembl:ENSRNOG00000045840(gene)|ensembl:ENSRNOG00000045978(gene)|ensembl:ENSRNOG00000046636(gene)|ensembl:ENSRNOG00000048215(gene)|ensembl:ENSRNOG00000048642(gene)|ensembl:ENSRNOG00000048735(gene)|ensembl:ENSRNOG00000050933(gene)|ensembl:ENSRNOG00000051891(gene)|ensembl:ENSRNOG00000054017(gene)|ensembl:ENSRNOG00000057690(gene)|ensembl:ENSRNOG00000058444(gene)|ensembl:ENSRNOT00000040210(transcript)|ensembl:ENSRNOT00000071512(transcript)|ensembl:ENSRNOT00000072147(transcript)|ensembl:ENSRNOT00000072286(transcript)|ensembl:ENSRNOT00000074109(transcript)|ensembl:ENSRNOT00000074198(transcript)|ensembl:ENSRNOT00000074526(transcript)|ensembl:ENSRNOT00000075065(transcript)|ensembl:ENSRNOT00000080490(transcript)|ensembl:ENSRNOT00000085381(transcript)|ensembl:ENSRNOT00000088408(transcript)|ensembl:ENSRNOT00000091201(transcript)|go:"GO:0000228"(nuclear chromosome)|go:"GO:0000786"(nucleosome)|go:"GO:0001503"(ossification)|go:"GO:0003677"(DNA binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006334"(nucleosome assembly)|go:"GO:0006335"(DNA replication-dependent chromatin assembly)|go:"GO:0006336"(DNA replication-independent chromatin assembly)|go:"GO:0006352"(DNA-templated transcription, initiation)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030154"(cell differentiation)|go:"GO:0032991"(protein-containing complex)|go:"GO:0045653"(negative regulation of megakaryocyte differentiation)|go:"GO:0046982"(protein heterodimerization activity)|interpro:IPR001951(Histone H4)|interpro:IPR004823("TATA box binding protein associated factor (TAF)")|interpro:IPR009072(Histone-fold)|interpro:IPR019809|interpro:IPR035425|mint:P62804|reactome:R-RNO-110330|reactome:R-RNO-110331|reactome:R-RNO-171306|reactome:R-RNO-201722|reactome:R-RNO-212300|reactome:R-RNO-2299718|reactome:R-RNO-2559580|reactome:R-RNO-2559582|reactome:R-RNO-2559586|reactome:R-RNO-3214841|reactome:R-RNO-3214842|reactome:R-RNO-3214847|reactome:R-RNO-3214858|reactome:R-RNO-427359|reactome:R-RNO-427413|reactome:R-RNO-4551638|reactome:R-RNO-5250924|reactome:R-RNO-5578749|reactome:R-RNO-5625886|reactome:R-RNO-5693565|reactome:R-RNO-5693571|reactome:R-RNO-5693607|reactome:R-RNO-606279|reactome:R-RNO-69473|reactome:R-RNO-73728|reactome:R-RNO-73772|reactome:R-RNO-8936459|reactome:R-RNO-9018519|reactome:R-RNO-9670095|rgd:620814|refseq:NP_001116941.1|refseq:NP_001258150.1|refseq:NP_073177.1|refseq:XP_003749904.3|refseq:XP_008761668.1|refseq:XP_008761670.1|refseq:XP_008769992.1|refseq:XP_008772221.1|refseq:XP_578415.4	-	-	-	figure legend:st1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10116(rat-brain-cortex)|taxid:10116(Rattus norvegicus brain cortex)	-	2020/10/30	2020/10/30	rogid:DtE+ZXAZKdCMvUW5K+jXQ5bH07M10116	rogid:LZSfhrpw0PcDREEoJ1UMkBvnUfA10116	rigid:3wclwrjZRvafcOruQOYnegkn54c	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q5XIE8	uniprotkb:Q00715	intact:EBI-15348306|ensembl:ENSRNOP00000023037	intact:EBI-931728	psi-mi:itm2b_rat(display_long)|uniprotkb:Itm2b(gene name)|psi-mi:Itm2b(display_short)|uniprotkb:Immature BRI2(gene name synonym)|uniprotkb:Transmembrane protein BRI(gene name synonym)	psi-mi:h2b1_rat(display_long)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Martins et al. (2018)	imex:IM-28469|pubmed:29476059	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26439741|imex:IM-28469-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSRNOG00000016271(gene)|ensembl:ENSRNOT00000023037(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001540"(amyloid-beta binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0010008"(endosome membrane)|go:"GO:0030660"(Golgi-associated vesicle membrane)|go:"GO:0031301"(integral component of organelle membrane)|go:"GO:0042985"(negative regulation of amyloid precursor protein biosynthetic process)|interpro:IPR007084(BRICHOS)|interpro:IPR040145|mint:Q5XIE8|refseq:NP_001006964.1|rgd:620727	refseq:NP_072173.1|interpro:IPR009072(Histone-fold)|interpro:IPR007125(Histone core)|interpro:IPR000558(Histone H2B)|mint:Q00715|go:"GO:0000786"(nucleosome)|go:"GO:0003677"(DNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006334"(nucleosome assembly)|go:"GO:0042742"(defense response to bacterium)|go:"GO:0046982"(protein heterodimerization activity)	-	-	-	figure legend:st1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10116(rat-brain-cortex)|taxid:10116(Rattus norvegicus brain cortex)	-	2020/10/30	2020/10/30	rogid:DtE+ZXAZKdCMvUW5K+jXQ5bH07M10116	rogid:MmU330IlxzGgIpswI5joy179agY10116	rigid:3wclwrjZRvafcOruQOYnegkn54c	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q5XIE8	uniprotkb:P34058	intact:EBI-15348306|ensembl:ENSRNOP00000023037	intact:EBI-917279|uniprotkb:Q1PSW2|uniprotkb:Q66H55|uniprotkb:Q68GV5|uniprotkb:Q9QWC6|ensembl:ENSRNOP00000026920	psi-mi:itm2b_rat(display_long)|uniprotkb:Itm2b(gene name)|psi-mi:Itm2b(display_short)|uniprotkb:Immature BRI2(gene name synonym)|uniprotkb:Transmembrane protein BRI(gene name synonym)	psi-mi:hs90b_rat(display_long)|uniprotkb:Heat shock 84 kDa(gene name synonym)|uniprotkb:Hsp90ab1(gene name)|psi-mi:Hsp90ab1(display_short)|uniprotkb:Hsp84(gene name synonym)|uniprotkb:Hspcb(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Martins et al. (2018)	imex:IM-28469|pubmed:29476059	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26439741|imex:IM-28469-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSRNOG00000016271(gene)|ensembl:ENSRNOT00000023037(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001540"(amyloid-beta binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0010008"(endosome membrane)|go:"GO:0030660"(Golgi-associated vesicle membrane)|go:"GO:0031301"(integral component of organelle membrane)|go:"GO:0042985"(negative regulation of amyloid precursor protein biosynthetic process)|interpro:IPR007084(BRICHOS)|interpro:IPR040145|mint:Q5XIE8|refseq:NP_001006964.1|rgd:620727	rgd:1303075|refseq:NP_001004082.3|ensembl:ENSRNOG00000019834(gene)|ensembl:ENSRNOT00000026920(transcript)|go:"GO:0001890"(placenta development)|go:"GO:0002134"(UTP binding)|go:"GO:0002135"(CTP binding)|go:"GO:0003725"(double-stranded RNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005525"(GTP binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006457"(protein folding)|go:"GO:0006986"(response to unfolded protein)|go:"GO:0007004"(telomere maintenance via telomerase)|go:"GO:0008180"(COP9 signalosome)|go:"GO:0009651"(response to salt stress)|go:"GO:0009986"(cell surface)|go:"GO:0010033"(response to organic substance)|go:"GO:0016234"(inclusion body)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0017098"(sulfonylurea receptor binding)|go:"GO:0019062"(virion attachment to host cell)|go:"GO:0019887"(protein kinase regulator activity)|go:"GO:0019900"(kinase binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0021955"(central nervous system neuron axonogenesis)|go:"GO:0030010"(establishment of cell polarity)|go:"GO:0030511"(positive regulation of transforming growth factor beta receptor signaling pathway)|go:"GO:0031072"(heat shock protein binding)|go:"GO:0031396"(regulation of protein ubiquitination)|go:"GO:0031526"(brush border membrane)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032092"(positive regulation of protein binding)|go:"GO:0032435"(negative regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0032516"(positive regulation of phosphoprotein phosphatase activity)|go:"GO:0032564"(dATP binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033138"(positive regulation of peptidyl-serine phosphorylation)|go:"GO:0034605"(cellular response to heat)|go:"GO:0034751"(aryl hydrocarbon receptor complex)|go:"GO:0042220"(response to cocaine)|go:"GO:0042277"(peptide binding)|go:"GO:0042307"(positive regulation of protein import into nucleus)|go:"GO:0042470"(melanosome)|go:"GO:0042493"|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0043008"(ATP-dependent protein binding)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043202"(lysosomal lumen)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0044183"(protein folding chaperone)|go:"GO:0044294"(dendritic growth cone)|go:"GO:0044295"(axonal growth cone)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0045597"(positive regulation of cell differentiation)|go:"GO:0045793"(positive regulation of cell size)|go:"GO:0046983"(protein dimerization activity)|go:"GO:0048156"(tau protein binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0048675"(axon extension)|go:"GO:0050821"(protein stabilization)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0051131"(chaperone-mediated protein complex assembly)|go:"GO:0051248"(negative regulation of protein metabolic process)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0051897"(positive regulation of protein kinase B signaling)|go:"GO:0051973"(positive regulation of telomerase activity)|go:"GO:0060334"(regulation of interferon-gamma-mediated signaling pathway)|go:"GO:0060338"(regulation of type I interferon-mediated signaling pathway)|go:"GO:0061635"(regulation of protein complex stability)|go:"GO:0061684"(chaperone-mediated autophagy)|go:"GO:0070182"(DNA polymerase binding)|go:"GO:0071353"(cellular response to interleukin-4)|go:"GO:0071407"(cellular response to organic cyclic compound)|go:"GO:0071902"(positive regulation of protein serine/threonine kinase activity)|go:"GO:0097435"(supramolecular fiber organization)|go:"GO:0097718"(disordered domain specific binding)|go:"GO:0120293"(dynein axonemal particle)|go:"GO:0140597"(protein carrier chaperone)|go:"GO:1901389"(negative regulation of transforming growth factor beta activation)|go:"GO:1901799"(negative regulation of proteasomal protein catabolic process)|go:"GO:1903660"(negative regulation of complement-dependent cytotoxicity)|go:"GO:1903827"|go:"GO:1904031"(positive regulation of cyclin-dependent protein kinase activity)|go:"GO:1905323"(telomerase holoenzyme complex assembly)|go:"GO:1990226"(histone methyltransferase binding)|go:"GO:1990565"(HSP90-CDC37 chaperone complex)|go:"GO:1990913"(sperm head plasma membrane)|go:"GO:1990917"(ooplasm)|go:"GO:2000010"(positive regulation of protein localization to cell surface)|interpro:IPR001404(Heat shock protein Hsp90)|interpro:IPR003594(ATP-binding region, ATPase-like)|interpro:IPR019805|interpro:IPR020568|interpro:IPR020575|interpro:IPR036890|interpro:IPR037196|mint:P34058|reactome:R-RNO-168928|reactome:R-RNO-2029482|reactome:R-RNO-3371497|reactome:R-RNO-3371511|reactome:R-RNO-3371568|reactome:R-RNO-3371571|reactome:R-RNO-399954|reactome:R-RNO-6798695|reactome:R-RNO-844456|reactome:R-RNO-8852276|reactome:R-RNO-8937144|reactome:R-RNO-8939211|reactome:R-RNO-9013418|reactome:R-RNO-9018519	-	-	-	figure legend:st1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10116(rat-brain-cortex)|taxid:10116(Rattus norvegicus brain cortex)	-	2020/10/30	2020/10/30	rogid:DtE+ZXAZKdCMvUW5K+jXQ5bH07M10116	rogid:5/MXDESVXdwuWna0s87Ap19aLMA10116	rigid:3wclwrjZRvafcOruQOYnegkn54c	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q5XIE8	uniprotkb:P82995	intact:EBI-15348306|ensembl:ENSRNOP00000023037	intact:EBI-919629|uniprotkb:Q91XW0|ensembl:ENSRNOP00000009556|ensembl:ENSRNOP00000075715	psi-mi:itm2b_rat(display_long)|uniprotkb:Itm2b(gene name)|psi-mi:Itm2b(display_short)|uniprotkb:Immature BRI2(gene name synonym)|uniprotkb:Transmembrane protein BRI(gene name synonym)	psi-mi:hs90a_rat(display_long)|uniprotkb:Hsp90aa1(gene name)|psi-mi:Hsp90aa1(display_short)|uniprotkb:Hspca(gene name synonym)|uniprotkb:Heat shock 86 kDa(gene name synonym)|uniprotkb:Hsp86(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Martins et al. (2018)	imex:IM-28469|pubmed:29476059	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26439741|imex:IM-28469-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSRNOG00000016271(gene)|ensembl:ENSRNOT00000023037(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001540"(amyloid-beta binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0010008"(endosome membrane)|go:"GO:0030660"(Golgi-associated vesicle membrane)|go:"GO:0031301"(integral component of organelle membrane)|go:"GO:0042985"(negative regulation of amyloid precursor protein biosynthetic process)|interpro:IPR007084(BRICHOS)|interpro:IPR040145|mint:Q5XIE8|refseq:NP_001006964.1|rgd:620727	refseq:XP_008763191.1|rgd:631409|refseq:NP_786937.1|ensembl:ENSRNOG00000007219(gene)|ensembl:ENSRNOG00000059714(gene)|ensembl:ENSRNOT00000009556(transcript)|ensembl:ENSRNOT00000086310(transcript)|go:"GO:0001764"(neuron migration)|go:"GO:0001934"(positive regulation of protein phosphorylation)|go:"GO:0002134"(UTP binding)|go:"GO:0002135"(CTP binding)|go:"GO:0002218"(activation of innate immune response)|go:"GO:0002230"(positive regulation of defense response to virus by host)|go:"GO:0003009"(skeletal muscle contraction)|go:"GO:0003729"(mRNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005525"(GTP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006457"(protein folding)|go:"GO:0007004"(telomere maintenance via telomerase)|go:"GO:0009408"(response to heat)|go:"GO:0009409"(response to cold)|go:"GO:0009651"(response to salt stress)|go:"GO:0009986"(cell surface)|go:"GO:0010592"(positive regulation of lamellipodium assembly)|go:"GO:0010659"(cardiac muscle cell apoptotic process)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0017098"(sulfonylurea receptor binding)|go:"GO:0019903"(protein phosphatase binding)|go:"GO:0021955"(central nervous system neuron axonogenesis)|go:"GO:0030010"(establishment of cell polarity)|go:"GO:0030235"(nitric-oxide synthase regulator activity)|go:"GO:0030911"(TPR domain binding)|go:"GO:0031396"(regulation of protein ubiquitination)|go:"GO:0031526"(brush border membrane)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032273"(positive regulation of protein polymerization)|go:"GO:0032564"(dATP binding)|go:"GO:0032728"(positive regulation of interferon-beta production)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033138"(positive regulation of peptidyl-serine phosphorylation)|go:"GO:0034605"(cellular response to heat)|go:"GO:0036126"(sperm flagellum)|go:"GO:0042220"(response to cocaine)|go:"GO:0042307"(positive regulation of protein import into nucleus)|go:"GO:0042470"(melanosome)|go:"GO:0042493"|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0043005"(neuron projection)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043202"(lysosomal lumen)|go:"GO:0043209"(myelin sheath)|go:"GO:0043627"(response to estrogen)|go:"GO:0044183"(protein folding chaperone)|go:"GO:0044294"(dendritic growth cone)|go:"GO:0044295"(axonal growth cone)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0045040"(protein insertion into mitochondrial outer membrane)|go:"GO:0045429"(positive regulation of nitric oxide biosynthetic process)|go:"GO:0045793"(positive regulation of cell size)|go:"GO:0046677"(response to antibiotic)|go:"GO:0048156"(tau protein binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0048675"(axon extension)|go:"GO:0050821"(protein stabilization)|go:"GO:0051020"(GTPase binding)|go:"GO:0051022"(Rho GDP-dissociation inhibitor binding)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0051131"(chaperone-mediated protein complex assembly)|go:"GO:0051897"(positive regulation of protein kinase B signaling)|go:"GO:0051973"(positive regulation of telomerase activity)|go:"GO:0060452"(positive regulation of cardiac muscle contraction)|go:"GO:0061635"(regulation of protein complex stability)|go:"GO:0061684"(chaperone-mediated autophagy)|go:"GO:0062023"(collagen-containing extracellular matrix)|go:"GO:0070182"(DNA polymerase binding)|go:"GO:0097110"(scaffold protein binding)|go:"GO:0097226"(sperm mitochondrial sheath)|go:"GO:0097524"(sperm plasma membrane)|go:"GO:0097718"(disordered domain specific binding)|go:"GO:0098586"(cellular response to virus)|go:"GO:0140597"(protein carrier chaperone)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|go:"GO:1902949"(positive regulation of tau-protein kinase activity)|go:"GO:1903364"(positive regulation of cellular protein catabolic process)|go:"GO:1903827"|go:"GO:1905323"(telomerase holoenzyme complex assembly)|go:"GO:1990782"(protein tyrosine kinase binding)|interpro:IPR001404(Heat shock protein Hsp90)|interpro:IPR003594(ATP-binding region, ATPase-like)|interpro:IPR019805|interpro:IPR020568|interpro:IPR020575|interpro:IPR036890|interpro:IPR037196|mint:P82995|reactome:R-RNO-1227986|reactome:R-RNO-1474151|reactome:R-RNO-168928|reactome:R-RNO-2029482|reactome:R-RNO-203615|reactome:R-RNO-2565942|reactome:R-RNO-3371497|reactome:R-RNO-3371511|reactome:R-RNO-3371568|reactome:R-RNO-3371571|reactome:R-RNO-380259|reactome:R-RNO-380270|reactome:R-RNO-380284|reactome:R-RNO-380320|reactome:R-RNO-399954|reactome:R-RNO-4420097|reactome:R-RNO-5218920|reactome:R-RNO-5620912|reactome:R-RNO-5675482|reactome:R-RNO-6798695|reactome:R-RNO-8852276|reactome:R-RNO-8854518|reactome:R-RNO-8863795|reactome:R-RNO-8939211|reactome:R-RNO-9009391|reactome:R-RNO-9013418|reactome:R-RNO-9018519|reactome:R-RNO-9652282	-	-	-	figure legend:st1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10116(rat-brain-cortex)|taxid:10116(Rattus norvegicus brain cortex)	-	2020/10/30	2020/10/30	rogid:DtE+ZXAZKdCMvUW5K+jXQ5bH07M10116	rogid:tqpvMNNqRR42cL/lpXrgcqJh0NE10116	rigid:3wclwrjZRvafcOruQOYnegkn54c	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q5XIE8	uniprotkb:P09606	intact:EBI-15348306|ensembl:ENSRNOP00000023037	intact:EBI-349265|uniprotkb:Q6P7Q9|ensembl:ENSRNOP00000065890	psi-mi:itm2b_rat(display_long)|uniprotkb:Itm2b(gene name)|psi-mi:Itm2b(display_short)|uniprotkb:Immature BRI2(gene name synonym)|uniprotkb:Transmembrane protein BRI(gene name synonym)	psi-mi:glna_rat(display_long)|uniprotkb:Glns(gene name synonym)|uniprotkb:Glul(gene name)|psi-mi:Glul(display_short)|uniprotkb:Glutamate--ammonia ligase(gene name synonym)|uniprotkb:Palmitoyltransferase GLUL(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Martins et al. (2018)	imex:IM-28469|pubmed:29476059	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26439741|imex:IM-28469-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSRNOG00000016271(gene)|ensembl:ENSRNOT00000023037(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001540"(amyloid-beta binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0010008"(endosome membrane)|go:"GO:0030660"(Golgi-associated vesicle membrane)|go:"GO:0031301"(integral component of organelle membrane)|go:"GO:0042985"(negative regulation of amyloid precursor protein biosynthetic process)|interpro:IPR007084(BRICHOS)|interpro:IPR040145|mint:Q5XIE8|refseq:NP_001006964.1|rgd:620727	rgd:2710|refseq:NP_058769.4|ensembl:ENSRNOG00000049560(gene)|ensembl:ENSRNOT00000075480(transcript)|go:"GO:0000287"(magnesium ion binding)|go:"GO:0001525"(angiogenesis)|go:"GO:0004356"(glutamate-ammonia ligase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005791"(rough endoplasmic reticulum)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006536"(glutamate metabolic process)|go:"GO:0006542"(glutamine biosynthetic process)|go:"GO:0008283"(cell population proliferation)|go:"GO:0009267"(cellular response to starvation)|go:"GO:0009749"(response to glucose)|go:"GO:0010594"(regulation of endothelial cell migration)|go:"GO:0016595"(glutamate binding)|go:"GO:0018345"(protein palmitoylation)|go:"GO:0019676"(ammonia assimilation cycle)|go:"GO:0019706"(protein-cysteine S-palmitoyltransferase activity)|go:"GO:0030145"(manganese ion binding)|go:"GO:0032024"(positive regulation of insulin secretion)|go:"GO:0032991"(protein-containing complex)|go:"GO:0042133"(neurotransmitter metabolic process)|go:"GO:0042254"(ribosome biogenesis)|go:"GO:0042802"(identical protein binding)|go:"GO:0042995"(cell projection)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0043679"(axon terminus)|go:"GO:0044297"(cell body)|go:"GO:0045503"(dynein light chain binding)|go:"GO:0050679"(positive regulation of epithelial cell proliferation)|go:"GO:0051968"(positive regulation of synaptic transmission, glutamatergic)|go:"GO:0097386"(glial cell projection)|go:"GO:1903670"(regulation of sprouting angiogenesis)|go:"GO:1904749"(regulation of protein localization to nucleolus)|interpro:IPR008146(Glutamine synthetase, catalytic region)|interpro:IPR008147(Glutamine synthetase, beta-Grasp)|interpro:IPR014746(Glutamine synthetase/guanido kinase, catalytic region)|interpro:IPR027302|interpro:IPR027303|interpro:IPR036651|mint:P09606|go:"GO:0043005"(neuron projection)|reactome:R-RNO-210455|reactome:R-RNO-8964539|go:"GO:0043204"(perikaryon)|go:"GO:0043209"(myelin sheath)	-	-	-	figure legend:st1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10116(rat-brain-cortex)|taxid:10116(Rattus norvegicus brain cortex)	-	2020/10/30	2020/10/30	rogid:DtE+ZXAZKdCMvUW5K+jXQ5bH07M10116	rogid:VN1L4Kl9yF9dxmvXpA3f1prv0tw10116	rigid:3wclwrjZRvafcOruQOYnegkn54c	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q5XIE8	uniprotkb:P19491	intact:EBI-15348306|ensembl:ENSRNOP00000023037	intact:EBI-77718|uniprotkb:Q9R174	psi-mi:itm2b_rat(display_long)|uniprotkb:Itm2b(gene name)|psi-mi:Itm2b(display_short)|uniprotkb:Immature BRI2(gene name synonym)|uniprotkb:Transmembrane protein BRI(gene name synonym)	psi-mi:gria2_rat(display_long)|uniprotkb:Gria2(gene name)|psi-mi:Gria2(display_short)|uniprotkb:Glur2(gene name synonym)|uniprotkb:GluR-B(gene name synonym)|uniprotkb:GluR-K2(gene name synonym)|uniprotkb:Glutamate receptor ionotropic, AMPA 2(gene name synonym)|uniprotkb:AMPA-selective glutamate receptor 2(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Martins et al. (2018)	imex:IM-28469|pubmed:29476059	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26439741|imex:IM-28469-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSRNOG00000016271(gene)|ensembl:ENSRNOT00000023037(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001540"(amyloid-beta binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0010008"(endosome membrane)|go:"GO:0030660"(Golgi-associated vesicle membrane)|go:"GO:0031301"(integral component of organelle membrane)|go:"GO:0042985"(negative regulation of amyloid precursor protein biosynthetic process)|interpro:IPR007084(BRICHOS)|interpro:IPR040145|mint:Q5XIE8|refseq:NP_001006964.1|rgd:620727	go:"GO:0019901"(protein kinase binding)|go:"GO:0030165"(PDZ domain binding)|go:"GO:0030425"(dendrite)|go:"GO:0030426"(growth cone)|go:"GO:0030672"(synaptic vesicle membrane)|go:"GO:0031623"(receptor internalization)|go:"GO:0032279"(asymmetric synapse)|go:"GO:0032281"(AMPA glutamate receptor complex)|go:"GO:0032839"(dendrite cytoplasm)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035235"(ionotropic glutamate receptor signaling pathway)|go:"GO:0035254"(glutamate receptor binding)|go:"GO:0036477"(somatodendritic compartment)|go:"GO:0038023"(signaling receptor activity)|go:"GO:0042734"(presynaptic membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0043005"(neuron projection)|go:"GO:0043025"(neuronal cell body)|interpro:IPR028082|rcsb pdb:1FTJ|rcsb pdb:1FTK|rcsb pdb:1FTL|rcsb pdb:1FTM|rcsb pdb:1FTO|rcsb pdb:1FW0|rcsb pdb:1GR2|rcsb pdb:1LB8|rcsb pdb:1LB9|rcsb pdb:1LBB|rcsb pdb:1LBC|rcsb pdb:1M5B|rcsb pdb:1M5C|rcsb pdb:1M5D|rcsb pdb:1M5E|rcsb pdb:1M5F|rcsb pdb:1MM6|rcsb pdb:1MM7|rcsb pdb:1MQD|rcsb pdb:1MQG|rcsb pdb:1MQH|rcsb pdb:1MQI|rcsb pdb:1MQJ|rcsb pdb:1MS7|rcsb pdb:1MXU|rcsb pdb:1MXV|rcsb pdb:1MXW|rcsb pdb:1MXX|rcsb pdb:1MXY|rcsb pdb:1MXZ|rcsb pdb:1MY0|rcsb pdb:1MY1|rcsb pdb:1MY2|rcsb pdb:1MY3|go:"GO:0043195"(terminal bouton)|go:"GO:0043197"(dendritic spine)|go:"GO:0043198"(dendritic shaft)|go:"GO:0043204"(perikaryon)|go:"GO:0045184"(establishment of protein localization)|go:"GO:0045202"(synapse)|go:"GO:0045211"(postsynaptic membrane)|go:"GO:0050806"(positive regulation of synaptic transmission)|go:"GO:0051117"(ATPase binding)|go:"GO:0051262"(protein tetramerization)|go:"GO:0051966"(regulation of synaptic transmission, glutamatergic)|go:"GO:0060992"(response to fungicide)|go:"GO:0097060"(synaptic membrane)|go:"GO:0098685"(Schaffer collateral - CA1 synapse)|go:"GO:0098839"(postsynaptic density membrane)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099055"(integral component of postsynaptic membrane)|go:"GO:0099056"(integral component of presynaptic membrane)|go:"GO:0099061"(integral component of postsynaptic density membrane)|go:"GO:0099544"(perisynaptic space)|go:"GO:1904315"(transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential)|interpro:IPR001320(Ionotropic glutamate receptor)|interpro:IPR001508(NMDA receptor)|interpro:IPR001828(Extracellular ligand-binding receptor)|interpro:IPR019594|go:"GO:0001540"(amyloid-beta binding)|go:"GO:0001919"(regulation of receptor recycling)|go:"GO:0004970"(ionotropic glutamate receptor activity)|go:"GO:0004971"(AMPA glutamate receptor activity)|go:"GO:0000149"(SNARE binding)|go:"GO:0005234"(extracellularly glutamate-gated ion channel activity)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0007268"(chemical synaptic transmission)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0008092"(cytoskeletal protein binding)|go:"GO:0008328"(ionotropic glutamate receptor complex)|go:"GO:0009986"(cell surface)|go:"GO:0010226"(response to lithium ion)|go:"GO:0014069"(postsynaptic density)|go:"GO:0015276"(ligand-gated ion channel activity)|go:"GO:0015277"(kainate selective glutamate receptor activity)|go:"GO:0016020"(membrane)|go:"GO:0019865"(immunoglobulin binding)|rcsb pdb:1MY4|rcsb pdb:1N0T|rcsb pdb:1NNK|rcsb pdb:1NNP|rcsb pdb:1P1N|rcsb pdb:1P1O|rcsb pdb:1P1Q|rcsb pdb:1P1U|rcsb pdb:1P1W|rcsb pdb:1SYH|rcsb pdb:1SYI|rcsb pdb:1WVJ|rcsb pdb:1XHY|rcsb pdb:2AIX|rcsb pdb:2AL4|rcsb pdb:2AL5|rcsb pdb:2ANJ|rcsb pdb:2CMO|rcsb pdb:2GFE|rcsb pdb:2I3V|rcsb pdb:2I3W|rcsb pdb:2P2A|rcsb pdb:2UXA|rcsb pdb:2XX7|rcsb pdb:2XX8|rcsb pdb:2XX9|rcsb pdb:2XXH|rcsb pdb:2XXI|rcsb pdb:3B6Q|rcsb pdb:5NIH|rcsb pdb:5NS9|rcsb pdb:5O9A|rcsb pdb:5OEW|rcsb pdb:5VHW|rcsb pdb:5VHX|rcsb pdb:5VHY|rcsb pdb:5VHZ|rcsb pdb:5VOT|rcsb pdb:5VOU|rcsb pdb:5VOV|rcsb pdb:5WEK|rcsb pdb:5WEL|rcsb pdb:5WEM|rcsb pdb:5WEN|rcsb pdb:5WEO|rcsb pdb:6DLZ|rcsb pdb:6DM0|rcsb pdb:6DM1|rcsb pdb:6FAZ|rcsb pdb:6FQG|rcsb pdb:6FQH|rcsb pdb:6FQI|rcsb pdb:6FQJ|rcsb pdb:6FQK|rcsb pdb:6GIV|rcsb pdb:6GL4|rcsb pdb:6HC9|rcsb pdb:6HCA|rcsb pdb:6HCB|rcsb pdb:6HCC|rcsb pdb:6HCH|rcsb pdb:6NJL|rcsb pdb:6NJM|rcsb pdb:6NJN|rcsb pdb:6O9G|rcsb pdb:6PEQ|rcsb pdb:6Q54|rcsb pdb:6Q60|rcsb pdb:6QKC|rcsb pdb:6QKZ|rcsb pdb:3B6T|rcsb pdb:3B6W|rcsb pdb:3B7D|rcsb pdb:3BBR|rcsb pdb:3BFT|rcsb pdb:3BFU|rcsb pdb:3BKI|rcsb pdb:3DP6|rcsb pdb:3H03|rcsb pdb:3H06|rcsb pdb:3H5V|rcsb pdb:3H5W|rcsb pdb:3H6T|rcsb pdb:3H6U|rcsb pdb:3H6V|rcsb pdb:3H6W|rcsb pdb:3HSY|rcsb pdb:3IJO|rcsb pdb:3IJX|rcsb pdb:3IK6|rcsb pdb:3IL1|rcsb pdb:3ILT|rcsb pdb:3ILU|rcsb pdb:3KG2|rcsb pdb:3KGC|rcsb pdb:3LSF|rcsb pdb:3LSL|rcsb pdb:3M3L|rcsb pdb:3N6V|rcsb pdb:3O28|rcsb pdb:3O29|rcsb pdb:3O2A|rcsb pdb:3O2J|rcsb pdb:3O6G|rcsb pdb:3O6H|rcsb pdb:3O6I|rcsb pdb:3PD8|rcsb pdb:3PD9|rcsb pdb:3PMV|rcsb pdb:3PMW|rcsb pdb:3PMX|rcsb pdb:6RUQ|rcsb pdb:6U5S|rcsb pdb:6U6I|rcsb pdb:6UCB|rcsb pdb:6UD4|rcsb pdb:6UD8|rcsb pdb:6XSR|rcsb pdb:6YK2|rcsb pdb:6YK3|rcsb pdb:6YK4|rcsb pdb:6YK5|rcsb pdb:6YK6|rcsb pdb:7OCA|rcsb pdb:7OCC|rcsb pdb:7OCD|rcsb pdb:7OCE|rcsb pdb:7OCF|reactome:R-RNO-399710|reactome:R-RNO-416993|reactome:R-RNO-438066|rcsb pdb:3RTF|rcsb pdb:3RTW|rcsb pdb:3T93|rcsb pdb:3T96|rcsb pdb:3T9H|rcsb pdb:3T9U|rcsb pdb:3T9V|rcsb pdb:3T9X|rcsb pdb:3TDJ|rcsb pdb:3TKD|rcsb pdb:3TZA|rcsb pdb:4FAT|rcsb pdb:4G8M|rcsb pdb:4GXS|rcsb pdb:4H8J|rcsb pdb:4IGT|rcsb pdb:4ISU|rcsb pdb:4IY5|rcsb pdb:4IY6|rcsb pdb:4L17|rcsb pdb:4LZ5|rcsb pdb:4LZ7|rcsb pdb:4LZ8|rcsb pdb:4N07|rcsb pdb:4O3A|rcsb pdb:4O3B|rcsb pdb:4O3C|rcsb pdb:4Q30|rcsb pdb:4U1O|rcsb pdb:4U1W|rcsb pdb:4U1X|rcsb pdb:4U1Y|rcsb pdb:4U1Z|rcsb pdb:4U21|rcsb pdb:4U22|rcsb pdb:4U23|rcsb pdb:4U2P|rcsb pdb:4U2Q|rcsb pdb:4U2R|rcsb pdb:4U4F|rcsb pdb:4U4G|rcsb pdb:4U4S|rcsb pdb:4U4X|rcsb pdb:4U5B|rcsb pdb:4U5C|rcsb pdb:4U5D|rcsb pdb:4U5E|rcsb pdb:4U5F|rcsb pdb:4UQ6|rcsb pdb:4UQJ|rcsb pdb:4UQK|rcsb pdb:4X48|rcsb pdb:4YMA|rcsb pdb:4YU0|rcsb pdb:4Z0I|rcsb pdb:5BUU|rcsb pdb:5CBR|rcsb pdb:5CBS|rcsb pdb:5ELV|rcsb pdb:5FHM|rcsb pdb:5FHN|rcsb pdb:5FHO|rcsb pdb:5FTH|rcsb pdb:5FTI|rcsb pdb:5FWX|rcsb pdb:5FWY|rcsb pdb:5IDE|rcsb pdb:5IDF|rcsb pdb:5JEI|rcsb pdb:5KBS|rcsb pdb:5KBT|rcsb pdb:5KBU|rcsb pdb:5KBV|rcsb pdb:5KK2|rcsb pdb:5L1B|rcsb pdb:5L1E|rcsb pdb:5L1F|rcsb pdb:5L1G|rcsb pdb:5L1H|rcsb pdb:5N6P|rcsb pdb:5NG9|refseq:NP_001077280.1|refseq:NP_058957.1|rgd:61862|mint:P19491|dip:DIP-30952N	-	-	-	figure legend:st1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10116(rat-brain-cortex)|taxid:10116(Rattus norvegicus brain cortex)	-	2020/10/30	2020/10/30	rogid:DtE+ZXAZKdCMvUW5K+jXQ5bH07M10116	rogid:zeQRRvspsIuRyA9kKA7kyIr8HqE10116	rigid:3wclwrjZRvafcOruQOYnegkn54c	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q5XIE8	uniprotkb:P47819	intact:EBI-15348306|ensembl:ENSRNOP00000023037	intact:EBI-931216|uniprotkb:Q7TQ31|uniprotkb:Q9R1Q3|uniprotkb:Q9Z2S0|uniprotkb:A7REI0|ensembl:ENSRNOP00000032389	psi-mi:itm2b_rat(display_long)|uniprotkb:Itm2b(gene name)|psi-mi:Itm2b(display_short)|uniprotkb:Immature BRI2(gene name synonym)|uniprotkb:Transmembrane protein BRI(gene name synonym)	psi-mi:gfap_rat(display_long)|uniprotkb:Gfap(gene name)|psi-mi:Gfap(display_short)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Martins et al. (2018)	imex:IM-28469|pubmed:29476059	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26439741|imex:IM-28469-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSRNOG00000016271(gene)|ensembl:ENSRNOT00000023037(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001540"(amyloid-beta binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0010008"(endosome membrane)|go:"GO:0030660"(Golgi-associated vesicle membrane)|go:"GO:0031301"(integral component of organelle membrane)|go:"GO:0042985"(negative regulation of amyloid precursor protein biosynthetic process)|interpro:IPR007084(BRICHOS)|interpro:IPR040145|mint:Q5XIE8|refseq:NP_001006964.1|rgd:620727	rgd:2679|refseq:NP_058705.2|ensembl:ENSRNOG00000002919(gene)|ensembl:ENSRNOT00000034401(transcript)|go:"GO:0005178"(integrin binding)|go:"GO:0005200"(structural constituent of cytoskeleton)|go:"GO:0005737"(cytoplasm)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005882"(intermediate filament)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0009611"(response to wounding)|go:"GO:0010467"(gene expression)|go:"GO:0010625"(positive regulation of Schwann cell proliferation)|go:"GO:0010977"(negative regulation of neuron projection development)|go:"GO:0014002"(astrocyte development)|go:"GO:0016020"(membrane)|go:"GO:0019900"(kinase binding)|go:"GO:0030198"(extracellular matrix organization)|go:"GO:0031102"(neuron projection regeneration)|go:"GO:0042802"(identical protein binding)|go:"GO:0042995"(cell projection)|go:"GO:0044297"(cell body)|go:"GO:0045103"(intermediate filament-based process)|go:"GO:0045109"(intermediate filament organization)|go:"GO:0051580"(regulation of neurotransmitter uptake)|go:"GO:0060020"(Bergmann glial cell differentiation)|go:"GO:0060252"(positive regulation of glial cell proliferation)|go:"GO:0060291"(long-term synaptic potentiation)|go:"GO:0070779"(D-aspartate import across plasma membrane)|go:"GO:0097386"(glial cell projection)|go:"GO:0097449"(astrocyte projection)|go:"GO:0097450"(astrocyte end-foot)|go:"GO:0098574"(cytoplasmic side of lysosomal membrane)|go:"GO:1904714"(regulation of chaperone-mediated autophagy)|interpro:IPR006821(Intermediate filament, DNA-binding region)|interpro:IPR018039|interpro:IPR027701|interpro:IPR039008|mint:P47819	-	-	-	figure legend:st1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10116(rat-brain-cortex)|taxid:10116(Rattus norvegicus brain cortex)	-	2020/10/30	2020/10/30	rogid:DtE+ZXAZKdCMvUW5K+jXQ5bH07M10116	rogid:ougdJqiJZjrvDV1vfVnCwcx9cFU10116	rigid:3wclwrjZRvafcOruQOYnegkn54c	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q5XIE8	uniprotkb:P08050	intact:EBI-15348306|ensembl:ENSRNOP00000023037	intact:EBI-476947|uniprotkb:Q53ZE1|ensembl:ENSRNOP00000001054	psi-mi:itm2b_rat(display_long)|uniprotkb:Itm2b(gene name)|psi-mi:Itm2b(display_short)|uniprotkb:Immature BRI2(gene name synonym)|uniprotkb:Transmembrane protein BRI(gene name synonym)	psi-mi:cxa1_rat(display_long)|uniprotkb:Gja1(gene name)|psi-mi:Gja1(display_short)|uniprotkb:Cxn-43(gene name synonym)|uniprotkb:Connexin-43(gene name synonym)|uniprotkb:Gap junction 43 kDa heart protein(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Martins et al. (2018)	imex:IM-28469|pubmed:29476059	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26439741|imex:IM-28469-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSRNOG00000016271(gene)|ensembl:ENSRNOT00000023037(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001540"(amyloid-beta binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0010008"(endosome membrane)|go:"GO:0030660"(Golgi-associated vesicle membrane)|go:"GO:0031301"(integral component of organelle membrane)|go:"GO:0042985"(negative regulation of amyloid precursor protein biosynthetic process)|interpro:IPR007084(BRICHOS)|interpro:IPR040145|mint:Q5XIE8|refseq:NP_001006964.1|rgd:620727	go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0030500"(regulation of bone mineralization)|go:"GO:0030660"(Golgi-associated vesicle membrane)|go:"GO:0032024"(positive regulation of insulin secretion)|go:"GO:0032277"(negative regulation of gonadotropin secretion)|go:"GO:0032355"(response to estradiol)|go:"GO:0032496"(response to lipopolysaccharide)|go:"GO:0032526"(response to retinoic acid)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034220"(ion transmembrane transport)|go:"GO:0034405"(response to fluid shear stress)|go:"GO:0034613"(cellular protein localization)|go:"GO:0034634"(glutathione transmembrane transporter activity)|go:"GO:0035050"(embryonic heart tube development)|go:"GO:0035437"(maintenance of protein localization in endoplasmic reticulum)|go:"GO:0042098"(T cell proliferation)|go:"GO:0042110"(T cell activation)|go:"GO:0030165"(PDZ domain binding)|ensembl:ENSRNOT00000001054(transcript)|go:"GO:0000132"(establishment of mitotic spindle orientation)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001649"(osteoblast differentiation)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0001764"(neuron migration)|go:"GO:0001937"(negative regulation of endothelial cell proliferation)|go:"GO:0001947"(heart looping)|ensembl:ENSRNOG00000000805(gene)|go:"GO:0002070"(epithelial cell maturation)|go:"GO:0002088"(lens development in camera-type eye)|go:"GO:0002544"(chronic inflammatory response)|go:"GO:0002931"(response to ischemia)|go:"GO:0003104"(positive regulation of glomerular filtration)|go:"GO:0003158"(endothelium development)|go:"GO:0042311"(vasodilation)|go:"GO:0042733"(embryonic digit morphogenesis)|go:"GO:0042908"(xenobiotic transport)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0043292"(contractile fiber)|go:"GO:0043403"(skeletal muscle tissue regeneration)|go:"GO:0043434"(response to peptide hormone)|go:"GO:0044291"(cell-cell contact zone)|go:"GO:0045121"(membrane raft)|go:"GO:0045216"(cell-cell junction organization)|go:"GO:0045732"(positive regulation of protein catabolic process)|go:"GO:0045844"(positive regulation of striated muscle tissue development)|go:"GO:0045907"(positive regulation of vasoconstriction)|go:"GO:0046697"(decidualization)|go:"GO:0046849"(bone remodeling)|go:"GO:0046850"(regulation of bone remodeling)|go:"GO:0048487"(beta-tubulin binding)|go:"GO:0048514"(blood vessel morphogenesis)|go:"GO:0048812"(neuron projection morphogenesis)|go:"GO:0051924"(regulation of calcium ion transport)|go:"GO:0055077"(gap junction hemi-channel activity)|go:"GO:0055085"(transmembrane transport)|go:"GO:0060044"(negative regulation of cardiac muscle cell proliferation)|go:"GO:0060156"(milk ejection reflex)|go:"GO:0060307"(regulation of ventricular cardiac muscle cell membrane repolarization)|go:"GO:0060348"(bone development)|go:"GO:0060371"(regulation of atrial cardiac muscle cell membrane depolarization)|go:"GO:0060373"(regulation of ventricular cardiac muscle cell membrane depolarization)|go:"GO:0061045"(negative regulation of wound healing)|go:"GO:0061337"(cardiac conduction)|go:"GO:0070160"(tight junction)|go:"GO:0071253"(connexin binding)|go:"GO:0071260"(cellular response to mechanical stimulus)|go:"GO:0071374"(cellular response to parathyroid hormone stimulus)|go:"GO:0071467"(cellular response to pH)|go:"GO:0097110"(scaffold protein binding)|go:"GO:0003294"(atrial ventricular junction remodeling)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005243"(gap junction channel activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005764"(lysosome)|go:"GO:0005768"(endosome)|go:"GO:0005769"(early endosome)|go:"GO:0005770"(late endosome)|go:"GO:0005771"(multivesicular body)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0005882"(intermediate filament)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0097718"(disordered domain specific binding)|go:"GO:0099111"(microtubule-based transport)|go:"GO:1904646"(cellular response to amyloid-beta)|go:"GO:0120162"(positive regulation of cold-induced thermogenesis)|go:"GO:1904707"(positive regulation of vascular associated smooth muscle cell proliferation)|go:"GO:1905332"(positive regulation of morphogenesis of an epithelium)|go:"GO:1905772"(positive regulation of mesodermal cell differentiation)|go:"GO:0140115"(export across plasma membrane)|go:"GO:1905867"(epididymis development)|go:"GO:1901164"(negative regulation of trophoblast cell migration)|go:"GO:1990782"(protein tyrosine kinase binding)|go:"GO:2000279"(negative regulation of DNA biosynthetic process)|go:"GO:2000648"(positive regulation of stem cell proliferation)|go:"GO:2000810"(regulation of bicellular tight junction assembly)|go:"GO:2000987"(positive regulation of behavioral fear response)|interpro:IPR000500(Connexins)|go:"GO:1903763"(gap junction channel activity involved in cell communication by electrical coupling)|interpro:IPR002261("Gap junction alpha-1 protein (Cx43)")|interpro:IPR013092(Connexin, N-terminal)|interpro:IPR013124("Gap junction alpha-1 protein (Cx43), C-terminal")|interpro:IPR017990|interpro:IPR019570|interpro:IPR034634|interpro:IPR035091|interpro:IPR038359|mint:P08050|rcsb pdb:1R5S|rcsb pdb:2N8T|rcsb pdb:3CYY|reactome:R-RNO-190840|reactome:R-RNO-190861|reactome:R-RNO-190873|reactome:R-RNO-191650|reactome:R-RNO-196025|reactome:R-RNO-9013406|go:"GO:0005916"(fascia adherens)|go:"GO:0008584"(male gonad development)|go:"GO:0009268"(response to pH)|go:"GO:0005921"(gap junction)|go:"GO:0005922"(connexin complex)|go:"GO:0009749"(response to glucose)|go:"GO:0010232"(vascular transport)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0010643"(cell communication by chemical coupling)|go:"GO:0010644"(cell communication by electrical coupling)|go:"GO:0010649"(regulation of cell communication by electrical coupling)|go:"GO:0010652"(positive regulation of cell communication by chemical coupling)|go:"GO:0014047"(glutamate secretion)|go:"GO:0014704"(intercalated disc)|go:"GO:0015075"(ion transmembrane transporter activity)|go:"GO:0015562"(efflux transmembrane transporter activity)|go:"GO:0015631"(tubulin binding)|go:"GO:0015867"(ATP transport)|go:"GO:0016020"(membrane)|go:"GO:0016264"(gap junction assembly)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0016328"(lateral plasma membrane)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0006915"(apoptotic process)|go:"GO:0022898"(regulation of transmembrane transporter activity)|go:"GO:0007154"(cell communication)|go:"GO:0030054"(cell junction)|go:"GO:0007165"(signal transduction)|go:"GO:0007204"(positive regulation of cytosolic calcium ion concentration)|go:"GO:0007267"(cell-cell signaling)|go:"GO:0007283"(spermatogenesis)|go:"GO:0007507"(heart development)|go:"GO:0007512"(adult heart development)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0008016"(regulation of heart contraction)|go:"GO:0008285"(negative regulation of cell population proliferation)|rgd:2690|refseq:NP_036699.1|dip:DIP-34793N	-	-	-	figure legend:st1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10116(rat-brain-cortex)|taxid:10116(Rattus norvegicus brain cortex)	-	2020/10/30	2020/10/30	rogid:DtE+ZXAZKdCMvUW5K+jXQ5bH07M10116	rogid:qRGPHCApRj9/xiPxo1KW9D/xE5w10116	rigid:3wclwrjZRvafcOruQOYnegkn54c	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q5XIE8	uniprotkb:P31596	intact:EBI-15348306|ensembl:ENSRNOP00000023037	intact:EBI-2649895	psi-mi:itm2b_rat(display_long)|uniprotkb:Itm2b(gene name)|psi-mi:Itm2b(display_short)|uniprotkb:Immature BRI2(gene name synonym)|uniprotkb:Transmembrane protein BRI(gene name synonym)	psi-mi:eaa2_rat(display_long)|uniprotkb:Slc1a2(gene name)|psi-mi:Slc1a2(display_short)|uniprotkb:Eaat2(gene name synonym)|uniprotkb:Glt1(gene name synonym)|uniprotkb:Sodium-dependent glutamate/aspartate transporter 2(gene name synonym)|uniprotkb:GLT-1(gene name synonym)|uniprotkb:Solute carrier family 1 member 2(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Martins et al. (2018)	imex:IM-28469|pubmed:29476059	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26439741|imex:IM-28469-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSRNOG00000016271(gene)|ensembl:ENSRNOT00000023037(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001540"(amyloid-beta binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0010008"(endosome membrane)|go:"GO:0030660"(Golgi-associated vesicle membrane)|go:"GO:0031301"(integral component of organelle membrane)|go:"GO:0042985"(negative regulation of amyloid precursor protein biosynthetic process)|interpro:IPR007084(BRICHOS)|interpro:IPR040145|mint:Q5XIE8|refseq:NP_001006964.1|rgd:620727	mint:P31596|rgd:3697|refseq:NP_058911.2|interpro:IPR001991("Sodium:dicarboxylate symporter")|interpro:IPR018107|refseq:NP_001289018.1|go:"GO:0005313"(L-glutamate transmembrane transporter activity)|go:"GO:0005314"(high-affinity glutamate transmembrane transporter activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006750"(glutathione biosynthetic process)|go:"GO:0006836"(neurotransmitter transport)|go:"GO:0007399"(nervous system development)|go:"GO:0007632"(visual behavior)|go:"GO:0008509"(anion transmembrane transporter activity)|go:"GO:0009416"(response to light stimulus)|go:"GO:0009611"(response to wounding)|go:"GO:0009986"(cell surface)|go:"GO:0010259"(multicellular organism aging)|go:"GO:0015501"("glutamate:sodium symporter activity")|go:"GO:0015813"(L-glutamate transmembrane transport)|go:"GO:0016020"(membrane)|go:"GO:0021537"(telencephalon development)|go:"GO:0030424"(axon)|go:"GO:0030534"(adult behavior)|go:"GO:0030673"(axolemma)|go:"GO:0031668"(cellular response to extracellular stimulus)|go:"GO:0031982"(vesicle)|go:"GO:0033229"(cysteine transmembrane transporter activity)|go:"GO:0035264"(multicellular organism growth)|go:"GO:0042493"|go:"GO:0042734"(presynaptic membrane)|go:"GO:0043005"(neuron projection)|go:"GO:0043197"(dendritic spine)|go:"GO:0043198"(dendritic shaft)|go:"GO:0043200"(response to amino acid)|go:"GO:0044297"(cell body)|go:"GO:0044306"(neuron projection terminus)|go:"GO:0045121"(membrane raft)|go:"GO:0045202"(synapse)|go:"GO:0046326"(positive regulation of glucose import)|go:"GO:0046872"(metal ion binding)|go:"GO:0070207"(protein homotrimerization)|go:"GO:0070779"(D-aspartate import across plasma membrane)|go:"GO:0071314"(cellular response to cocaine)|go:"GO:0097449"(astrocyte projection)|go:"GO:0098656"(anion transmembrane transport)|go:"GO:0098712"(L-glutamate import across plasma membrane)|go:"GO:0098796"(membrane protein complex)|go:"GO:0098810"(neurotransmitter reuptake)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099056"(integral component of presynaptic membrane)|reactome:R-RNO-210455|reactome:R-RNO-210500|reactome:R-RNO-425393|interpro:IPR036458	-	-	-	figure legend:st1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10116(rat-brain-cortex)|taxid:10116(Rattus norvegicus brain cortex)	-	2020/10/30	2020/10/30	rogid:DtE+ZXAZKdCMvUW5K+jXQ5bH07M10116	rogid:JednhWybRDznXCugAtjbnX/1JmM10116	rigid:3wclwrjZRvafcOruQOYnegkn54c	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q5XIE8	uniprotkb:P24942	intact:EBI-15348306|ensembl:ENSRNOP00000023037	intact:EBI-26373259|uniprotkb:Q9JK43	psi-mi:itm2b_rat(display_long)|uniprotkb:Itm2b(gene name)|psi-mi:Itm2b(display_short)|uniprotkb:Immature BRI2(gene name synonym)|uniprotkb:Transmembrane protein BRI(gene name synonym)	psi-mi:eaa1_rat(display_long)|uniprotkb:Glial glutamate transporter(gene name synonym)|uniprotkb:Sodium-dependent glutamate/aspartate transporter 1(gene name synonym)|uniprotkb:Solute carrier family 1 member 3(gene name synonym)|uniprotkb:Slc1a3(gene name)|psi-mi:Slc1a3(display_short)|uniprotkb:Eaat1(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Martins et al. (2018)	imex:IM-28469|pubmed:29476059	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26439741|imex:IM-28469-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSRNOG00000016271(gene)|ensembl:ENSRNOT00000023037(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001540"(amyloid-beta binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0010008"(endosome membrane)|go:"GO:0030660"(Golgi-associated vesicle membrane)|go:"GO:0031301"(integral component of organelle membrane)|go:"GO:0042985"(negative regulation of amyloid precursor protein biosynthetic process)|interpro:IPR007084(BRICHOS)|interpro:IPR040145|mint:Q5XIE8|refseq:NP_001006964.1|rgd:620727	go:"GO:0015172"(acidic amino acid transmembrane transporter activity)|go:"GO:0015501"("glutamate:sodium symporter activity")|go:"GO:0015813"(L-glutamate transmembrane transport)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016595"(glutamate binding)|go:"GO:0016597"(amino acid binding)|go:"GO:0021545"(cranial nerve development)|go:"GO:0031223"(auditory behavior)|go:"GO:0042493"|go:"GO:0042995"(cell projection)|go:"GO:0043005"(neuron projection)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043197"(dendritic spine)|go:"GO:0043490"(malate-aspartate shuttle)|go:"GO:0045202"(synapse)|go:"GO:0046677"(response to antibiotic)|go:"GO:0046872"(metal ion binding)|go:"GO:0048667"(cell morphogenesis involved in neuron differentiation)|go:"GO:0050806"(positive regulation of synaptic transmission)|go:"GO:0050885"(neuromuscular process controlling balance)|go:"GO:0051938"(L-glutamate import)|go:"GO:0070779"(D-aspartate import across plasma membrane)|go:"GO:0071314"(cellular response to cocaine)|go:"GO:0071805"(potassium ion transmembrane transport)|go:"GO:0071944"(cell periphery)|go:"GO:0098712"(L-glutamate import across plasma membrane)|go:"GO:0005313"(L-glutamate transmembrane transporter activity)|go:"GO:0005314"(high-affinity glutamate transmembrane transporter activity)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006836"(neurotransmitter transport)|go:"GO:0006883"(cellular sodium ion homeostasis)|go:"GO:0007605"(sensory perception of sound)|go:"GO:0009416"(response to light stimulus)|go:"GO:0009449"(gamma-aminobutyric acid biosynthetic process)|go:"GO:0009611"(response to wounding)|go:"GO:0009925"(basal plasma membrane)|go:"GO:0009986"(cell surface)|go:"GO:0010035"(response to inorganic substance)|go:"GO:0098796"(membrane protein complex)|go:"GO:0140009"(L-aspartate import across plasma membrane)|go:"GO:1902476"(chloride transmembrane transport)|reactome:R-RNO-210455|reactome:R-RNO-210500|reactome:R-RNO-425393|rgd:3698|mint:P24942|refseq:NP_001276870.1|refseq:NP_001276871.1|refseq:NP_001276872.1|refseq:NP_062098.1|interpro:IPR001991("Sodium:dicarboxylate symporter")|interpro:IPR018107|interpro:IPR036458	-	-	-	figure legend:st1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10116(rat-brain-cortex)|taxid:10116(Rattus norvegicus brain cortex)	-	2020/10/30	2020/10/30	rogid:DtE+ZXAZKdCMvUW5K+jXQ5bH07M10116	rogid:c22nOB/elZ8k3t1KJiZ3jyW+aSs10116	rigid:3wclwrjZRvafcOruQOYnegkn54c	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q5XIE8	uniprotkb:Q66HD0	intact:EBI-15348306|ensembl:ENSRNOP00000023037	intact:EBI-6249734|uniprotkb:A6IFJ6	psi-mi:itm2b_rat(display_long)|uniprotkb:Itm2b(gene name)|psi-mi:Itm2b(display_short)|uniprotkb:Immature BRI2(gene name synonym)|uniprotkb:Transmembrane protein BRI(gene name synonym)	psi-mi:enpl_rat(display_long)|uniprotkb:Hsp90b1(gene name)|psi-mi:Hsp90b1(display_short)|uniprotkb:Grp94(gene name synonym)|uniprotkb:Tra1(gene name synonym)|uniprotkb:94 kDa glucose-regulated protein(gene name synonym)|uniprotkb:Heat shock protein 90 kDa beta member 1(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Martins et al. (2018)	imex:IM-28469|pubmed:29476059	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26439741|imex:IM-28469-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSRNOG00000016271(gene)|ensembl:ENSRNOT00000023037(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001540"(amyloid-beta binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0010008"(endosome membrane)|go:"GO:0030660"(Golgi-associated vesicle membrane)|go:"GO:0031301"(integral component of organelle membrane)|go:"GO:0042985"(negative regulation of amyloid precursor protein biosynthetic process)|interpro:IPR007084(BRICHOS)|interpro:IPR040145|mint:Q5XIE8|refseq:NP_001006964.1|rgd:620727	mint:Q66HD0|rgd:1310482|refseq:NP_001012197.2|interpro:IPR003594(ATP-binding region, ATPase-like)|interpro:IPR019805|interpro:IPR001404(Heat shock protein Hsp90)|interpro:IPR020575|interpro:IPR020568|go:"GO:0001666"(response to hypoxia)|go:"GO:0003723"(RNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005788"(endoplasmic reticulum lumen)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005790"(smooth endoplasmic reticulum)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006457"(protein folding)|go:"GO:0019903"(protein phosphatase binding)|go:"GO:0030433"(ubiquitin-dependent ERAD pathway)|go:"GO:0030496"(midbody)|go:"GO:0030970"(retrograde protein transport, ER to cytosol)|go:"GO:0031247"(actin rod assembly)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033018"(sarcoplasmic reticulum lumen)|go:"GO:0034663"(endoplasmic reticulum chaperone complex)|go:"GO:0042470"(melanosome)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043666"(regulation of phosphoprotein phosphatase activity)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0050750"(low-density lipoprotein particle receptor binding)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0071287"(cellular response to manganese ion)|go:"GO:0071318"(cellular response to ATP)|reactome:R-RNO-1679131|reactome:R-RNO-3000480|reactome:R-RNO-381426|reactome:R-RNO-6785807|reactome:R-RNO-8957275|interpro:IPR036890|interpro:IPR037196	-	-	-	figure legend:st1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10116(rat-brain-cortex)|taxid:10116(Rattus norvegicus brain cortex)	-	2020/10/30	2020/10/30	rogid:DtE+ZXAZKdCMvUW5K+jXQ5bH07M10116	rogid:KSJbfWJ3pXbaBW15MDZ6syUs/4U10116	rigid:3wclwrjZRvafcOruQOYnegkn54c	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q5XIE8	uniprotkb:Q5PPJ9	intact:EBI-15348306|ensembl:ENSRNOP00000023037	intact:EBI-8848640	psi-mi:itm2b_rat(display_long)|uniprotkb:Itm2b(gene name)|psi-mi:Itm2b(display_short)|uniprotkb:Immature BRI2(gene name synonym)|uniprotkb:Transmembrane protein BRI(gene name synonym)	psi-mi:shlb2_rat(display_long)|uniprotkb:Sh3glb2(gene name)|psi-mi:Sh3glb2(display_short)|uniprotkb:SH3 domain-containing GRB2-like protein B2(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Martins et al. (2018)	imex:IM-28469|pubmed:29476059	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26439741|imex:IM-28469-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSRNOG00000016271(gene)|ensembl:ENSRNOT00000023037(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001540"(amyloid-beta binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0010008"(endosome membrane)|go:"GO:0030660"(Golgi-associated vesicle membrane)|go:"GO:0031301"(integral component of organelle membrane)|go:"GO:0042985"(negative regulation of amyloid precursor protein biosynthetic process)|interpro:IPR007084(BRICHOS)|interpro:IPR040145|mint:Q5XIE8|refseq:NP_001006964.1|rgd:620727	mint:Q5PPJ9|interpro:IPR027267|interpro:IPR004148(BAR)|interpro:IPR001452(Src homology-3)|refseq:NP_001009692.1|rgd:1305886|refseq:XP_006233880.1|interpro:IPR035640|interpro:IPR036028|go:"GO:0005737"(cytoplasm)|go:"GO:0042802"(identical protein binding)	-	-	-	figure legend:st1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10116(rat-brain-cortex)|taxid:10116(Rattus norvegicus brain cortex)	-	2020/10/30	2020/10/30	rogid:DtE+ZXAZKdCMvUW5K+jXQ5bH07M10116	rogid:Zm8xh0SeU1baeRfRtOvo8uae/n810116	rigid:3wclwrjZRvafcOruQOYnegkn54c	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q5XIE8	uniprotkb:P85834	intact:EBI-15348306|ensembl:ENSRNOP00000023037	intact:EBI-2640608|ensembl:ENSRNOP00000025203	psi-mi:itm2b_rat(display_long)|uniprotkb:Itm2b(gene name)|psi-mi:Itm2b(display_short)|uniprotkb:Immature BRI2(gene name synonym)|uniprotkb:Transmembrane protein BRI(gene name synonym)	psi-mi:eftu_rat(display_long)|uniprotkb:Tufm(gene name)|psi-mi:Tufm(display_short)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Martins et al. (2018)	imex:IM-28469|pubmed:29476059	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26439741|imex:IM-28469-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSRNOG00000016271(gene)|ensembl:ENSRNOT00000023037(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001540"(amyloid-beta binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0010008"(endosome membrane)|go:"GO:0030660"(Golgi-associated vesicle membrane)|go:"GO:0031301"(integral component of organelle membrane)|go:"GO:0042985"(negative regulation of amyloid precursor protein biosynthetic process)|interpro:IPR007084(BRICHOS)|interpro:IPR040145|mint:Q5XIE8|refseq:NP_001006964.1|rgd:620727	rgd:1305501|refseq:NP_001099765.1|ensembl:ENSRNOG00000018604(gene)|ensembl:ENSRNOT00000025203(transcript)|go:"GO:0003746"(translation elongation factor activity)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005739"(mitochondrion)|go:"GO:0006414"(translational elongation)|go:"GO:0042645"(mitochondrial nucleoid)|go:"GO:0045202"(synapse)|go:"GO:0045471"(response to ethanol)|go:"GO:0070125"(mitochondrial translational elongation)|interpro:IPR000795(Protein synthesis factor, GTP-binding)|interpro:IPR004160(Translation elongation factor EFTu/EF1A, C-terminal)|interpro:IPR004161(Translation elongation factor EFTu/EF1A, domain 2)|interpro:IPR004541(Translation elongation factor EFTu/EF1A, bacterial and organelle)|interpro:IPR009000(Translation elongation and initiation factors/Ribosomal, beta-barrel)|interpro:IPR009001(Translation elongation factor EF1A/initiation factor IF2gamma, C-terminal)|interpro:IPR027417|interpro:IPR031157|interpro:IPR033720|interpro:IPR041709|mint:P85834	-	-	-	figure legend:st1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10116(rat-brain-cortex)|taxid:10116(Rattus norvegicus brain cortex)	-	2020/10/30	2020/10/30	rogid:DtE+ZXAZKdCMvUW5K+jXQ5bH07M10116	rogid:7ijVJSb0XSiqlNjp70i4FXEF2z810116	rigid:3wclwrjZRvafcOruQOYnegkn54c	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q5XIE8	uniprotkb:P05197	intact:EBI-15348306|ensembl:ENSRNOP00000023037	intact:EBI-915895|uniprotkb:P97619|ensembl:ENSRNOP00000041821	psi-mi:itm2b_rat(display_long)|uniprotkb:Itm2b(gene name)|psi-mi:Itm2b(display_short)|uniprotkb:Immature BRI2(gene name synonym)|uniprotkb:Transmembrane protein BRI(gene name synonym)	psi-mi:ef2_rat(display_long)|uniprotkb:Eef2(gene name)|psi-mi:Eef2(display_short)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Martins et al. (2018)	imex:IM-28469|pubmed:29476059	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26439741|imex:IM-28469-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSRNOG00000016271(gene)|ensembl:ENSRNOT00000023037(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001540"(amyloid-beta binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0010008"(endosome membrane)|go:"GO:0030660"(Golgi-associated vesicle membrane)|go:"GO:0031301"(integral component of organelle membrane)|go:"GO:0042985"(negative regulation of amyloid precursor protein biosynthetic process)|interpro:IPR007084(BRICHOS)|interpro:IPR040145|mint:Q5XIE8|refseq:NP_001006964.1|rgd:620727	rgd:61979|refseq:NP_058941.1|ensembl:ENSRNOG00000020266(gene)|ensembl:ENSRNOT00000047450(transcript)|go:"GO:0002039"(p53 binding)|go:"GO:0002244"(hematopoietic progenitor cell differentiation)|go:"GO:0002931"(response to ischemia)|go:"GO:0003009"(skeletal muscle contraction)|go:"GO:0003723"(RNA binding)|go:"GO:0003746"(translation elongation factor activity)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005844"(polysome)|go:"GO:0005886"(plasma membrane)|go:"GO:0006414"(translational elongation)|go:"GO:0007568"(aging)|go:"GO:0008097"(5S rRNA binding)|go:"GO:0014009"(glial cell proliferation)|go:"GO:0016235"(aggresome)|go:"GO:0019901"(protein kinase binding)|go:"GO:0032355"(response to estradiol)|go:"GO:0034976"(response to endoplasmic reticulum stress)|go:"GO:0035914"(skeletal muscle cell differentiation)|go:"GO:0042493"|go:"GO:0042542"(response to hydrogen peroxide)|go:"GO:0042788"(polysomal ribosome)|go:"GO:0043022"(ribosome binding)|go:"GO:0045121"(membrane raft)|go:"GO:0045202"(synapse)|go:"GO:0045471"(response to ethanol)|go:"GO:0045727"(positive regulation of translation)|go:"GO:0051015"(actin filament binding)|go:"GO:0051593"(response to folic acid)|go:"GO:1990416"(cellular response to brain-derived neurotrophic factor stimulus)|go:"GO:1990904"(ribonucleoprotein complex)|go:"GO:2000767"(positive regulation of cytoplasmic translation)|interpro:IPR000640(Translation elongation factor EFG/EF2, C-terminal)|interpro:IPR000795(Protein synthesis factor, GTP-binding)|interpro:IPR004161(Translation elongation factor EFTu/EF1A, domain 2)|interpro:IPR005225(Small GTP-binding protein)|interpro:IPR005517(Translation elongation factor EFG/EF2, domain IV)|interpro:IPR009000(Translation elongation and initiation factors/Ribosomal, beta-barrel)|interpro:IPR014721(Ribosomal protein S5 domain 2-type fold)|interpro:IPR020568|interpro:IPR027417|interpro:IPR031157|interpro:IPR035647|interpro:IPR041095|mint:P05197|reactome:R-RNO-156902|reactome:R-RNO-5358493|reactome:R-RNO-6798695	-	-	-	figure legend:st1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10116(rat-brain-cortex)|taxid:10116(Rattus norvegicus brain cortex)	-	2020/10/30	2020/10/30	rogid:DtE+ZXAZKdCMvUW5K+jXQ5bH07M10116	rogid:JpTfRnV5VR9V+mR+c5hxYJ0FsM410116	rigid:3wclwrjZRvafcOruQOYnegkn54c	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q5XIE8	uniprotkb:P31016	intact:EBI-15348306|ensembl:ENSRNOP00000023037	intact:EBI-375655|uniprotkb:P97631|ensembl:ENSRNOP00000059045	psi-mi:itm2b_rat(display_long)|uniprotkb:Itm2b(gene name)|psi-mi:Itm2b(display_short)|uniprotkb:Immature BRI2(gene name synonym)|uniprotkb:Transmembrane protein BRI(gene name synonym)	psi-mi:dlg4_rat(display_long)|uniprotkb:Dlg4(gene name)|psi-mi:Dlg4(display_short)|uniprotkb:Dlgh4(gene name synonym)|uniprotkb:Postsynaptic density protein 95(gene name synonym)|uniprotkb:Synapse-associated protein 90(gene name synonym)|uniprotkb:Psd95(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Martins et al. (2018)	imex:IM-28469|pubmed:29476059	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26439741|imex:IM-28469-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSRNOG00000016271(gene)|ensembl:ENSRNOT00000023037(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001540"(amyloid-beta binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0010008"(endosome membrane)|go:"GO:0030660"(Golgi-associated vesicle membrane)|go:"GO:0031301"(integral component of organelle membrane)|go:"GO:0042985"(negative regulation of amyloid precursor protein biosynthetic process)|interpro:IPR007084(BRICHOS)|interpro:IPR040145|mint:Q5XIE8|refseq:NP_001006964.1|rgd:620727	go:"GO:0030165"(PDZ domain binding)|go:"GO:0030425"(dendrite)|go:"GO:0030863"(cortical cytoskeleton)|go:"GO:0031234"(extrinsic component of cytoplasmic side of plasma membrane)|go:"GO:0031594"(neuromuscular junction)|go:"GO:0031697"(beta-1 adrenergic receptor binding)|go:"GO:0031698"(beta-2 adrenergic receptor binding)|go:"GO:0031748"(D1 dopamine receptor binding)|go:"GO:0031812"(P2Y1 nucleotide receptor binding)|go:"GO:0032281"(AMPA glutamate receptor complex)|go:"GO:0032839"(dendrite cytoplasm)|go:"GO:0033130"(acetylcholine receptor binding)|go:"GO:0035176"(social behavior)|go:"GO:0035254"(glutamate receptor binding)|go:"GO:0035255"(ionotropic glutamate receptor binding)|go:"GO:0035418"(protein localization to synapse)|go:"GO:0035641"(locomotory exploration behavior)|go:"GO:0035865"(cellular response to potassium ion)|go:"GO:0043005"(neuron projection)|go:"GO:0043113"(receptor clustering)|go:"GO:0043197"(dendritic spine)|go:"GO:0044224"(juxtaparanode region of axon)|go:"GO:0044300"(cerebellar mossy fiber)|go:"GO:0044306"(neuron projection terminus)|go:"GO:0044309"(neuron spine)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045161"(neuronal ion channel clustering)|go:"GO:0045184"(establishment of protein localization)|go:"GO:0045202"(synapse)|go:"GO:0045211"(postsynaptic membrane)|go:"GO:0048168"(regulation of neuronal synaptic plasticity)|go:"GO:0048169"(regulation of long-term neuronal synaptic plasticity)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0050806"(positive regulation of synaptic transmission)|go:"GO:0050885"(neuromuscular process controlling balance)|go:"GO:0060076"(excitatory synapse)|go:"GO:0060997"(dendritic spine morphogenesis)|go:"GO:0061098"(positive regulation of protein tyrosine kinase activity)|go:"GO:0099031"(anchored component of postsynaptic density membrane)|go:"GO:0065003"(protein-containing complex assembly)|go:"GO:0071625"(vocalization behavior)|go:"GO:0071944"(cell periphery)|go:"GO:0097060"(synaptic membrane)|go:"GO:0097061"(dendritic spine organization)|go:"GO:0097109"(neuroligin family protein binding)|go:"GO:0099645"(neurotransmitter receptor localization to postsynaptic specialization membrane)|go:"GO:0150012"(positive regulation of neuron projection arborization)|go:"GO:0097110"(scaffold protein binding)|go:"GO:1904719"(positive regulation of AMPA glutamate receptor clustering)|go:"GO:0097113"(AMPA glutamate receptor clustering)|go:"GO:0097120"(receptor localization to synapse)|go:"GO:0098609"(cell-cell adhesion)|go:"GO:0098794"(postsynapse)|go:"GO:0098839"(postsynaptic density membrane)|go:"GO:0098919"(structural constituent of postsynaptic density)|go:"GO:0098970"(postsynaptic neurotransmitter receptor diffusion trapping)|go:"GO:2000310"(regulation of NMDA receptor activity)|go:"GO:2000463"(positive regulation of excitatory postsynaptic potential)|go:"GO:2000821"(regulation of grooming behavior)|interpro:IPR001452(Src homology-3)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR008144(Guanylate kinase)|interpro:IPR008145(Guanylate kinase/L-type calcium channel region)|rcsb pdb:1TP3|interpro:IPR016313("Membrane-associated guanylate kinase (MAGUK) scaffold protein")|interpro:IPR019583|interpro:IPR019590|interpro:IPR020590|interpro:IPR027417|interpro:IPR036028|interpro:IPR036034|mint:P31016|rcsb pdb:1BE9|rcsb pdb:1BFE|rcsb pdb:1IU0|rcsb pdb:1IU2|rcsb pdb:1JXM|rcsb pdb:1JXO|rcsb pdb:1KJW|rcsb pdb:1QLC|rcsb pdb:1RGR|rcsb pdb:5MZ7|rcsb pdb:5W72|rcsb pdb:5YPO|rcsb pdb:5YPR|rcsb pdb:7CQF|reactome:R-RNO-399719|reactome:R-RNO-438066|reactome:R-RNO-451308|reactome:R-RNO-5625900|reactome:R-RNO-5673001|reactome:R-RNO-5682910|reactome:R-RNO-6794361|reactome:R-RNO-8849932|rcsb pdb:1TP5|rcsb pdb:1TQ3|rcsb pdb:2KA9|rcsb pdb:2MHO|rcsb pdb:2XKX|rcsb pdb:3GSL|rcsb pdb:3WP0|rcsb pdb:3WP1|rcsb pdb:5B64|rcsb pdb:5D13|rcsb pdb:5GNV|rcsb pdb:5HDY|rcsb pdb:5HEB|rcsb pdb:5HED|rcsb pdb:5HET|rcsb pdb:5HEY|rcsb pdb:5HF1|rcsb pdb:5HF4|rcsb pdb:5HFB|rcsb pdb:5HFC|rcsb pdb:5HFD|rcsb pdb:5HFE|rcsb pdb:5HFF|ensembl:ENSRNOG00000018526(gene)|ensembl:ENSRNOT00000068493(transcript)|go:"GO:0002091"(negative regulation of receptor internalization)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005109"(frizzled binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0007204"(positive regulation of cytosolic calcium ion concentration)|go:"GO:0007268"(chemical synaptic transmission)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008328"(ionotropic glutamate receptor complex)|go:"GO:0014069"(postsynaptic density)|go:"GO:0016020"(membrane)|go:"GO:0016188"(synaptic vesicle maturation)|go:"GO:0019865"(immunoglobulin binding)|go:"GO:0019894"(kinesin binding)|go:"GO:0019900"(kinase binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0019903"(protein phosphatase binding)|go:"GO:0030054"(cell junction)|rgd:68424|refseq:NP_062567.1|dip:DIP-29264N	-	-	-	figure legend:st1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10116(rat-brain-cortex)|taxid:10116(Rattus norvegicus brain cortex)	-	2020/10/30	2020/10/30	rogid:DtE+ZXAZKdCMvUW5K+jXQ5bH07M10116	rogid:4oWbxT/HVvWQqdbFqt3htRuQNpw10116	rigid:3wclwrjZRvafcOruQOYnegkn54c	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q5XIE8	uniprotkb:P25809	intact:EBI-15348306|ensembl:ENSRNOP00000023037	intact:EBI-2255977	psi-mi:itm2b_rat(display_long)|uniprotkb:Itm2b(gene name)|psi-mi:Itm2b(display_short)|uniprotkb:Immature BRI2(gene name synonym)|uniprotkb:Transmembrane protein BRI(gene name synonym)	psi-mi:kcru_rat(display_long)|uniprotkb:Ckmt1(gene name)|psi-mi:Ckmt1(display_short)|uniprotkb:Ckmt(gene name synonym)|uniprotkb:Ubiquitous mitochondrial creatine kinase(gene name synonym)|uniprotkb:Acidic-type mitochondrial creatine kinase(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Martins et al. (2018)	imex:IM-28469|pubmed:29476059	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26439741|imex:IM-28469-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSRNOG00000016271(gene)|ensembl:ENSRNOT00000023037(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001540"(amyloid-beta binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0010008"(endosome membrane)|go:"GO:0030660"(Golgi-associated vesicle membrane)|go:"GO:0031301"(integral component of organelle membrane)|go:"GO:0042985"(negative regulation of amyloid precursor protein biosynthetic process)|interpro:IPR007084(BRICHOS)|interpro:IPR040145|mint:Q5XIE8|refseq:NP_001006964.1|rgd:620727	rgd:61976|interpro:IPR022415|interpro:IPR022414|interpro:IPR022413|interpro:IPR014746(Glutamine synthetase/guanido kinase, catalytic region)|interpro:IPR000749("ATP:guanido phosphotransferase")|mint:P25809|interpro:IPR036802|go:"GO:0001822"(kidney development)|go:"GO:0004111"(creatine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0007420"(brain development)|go:"GO:0007519"(skeletal muscle tissue development)|go:"GO:0016301"(kinase activity)|go:"GO:0021549"(cerebellum development)|go:"GO:0032091"(negative regulation of protein binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043204"(perikaryon)|go:"GO:0044289"(mitochondrial inner-outer membrane contact site)|go:"GO:0046314"(phosphocreatine biosynthetic process)|go:"GO:0048565"(digestive tract development)|reactome:R-RNO-71288	-	-	-	figure legend:st1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10116(rat-brain-cortex)|taxid:10116(Rattus norvegicus brain cortex)	-	2020/10/30	2020/10/30	rogid:DtE+ZXAZKdCMvUW5K+jXQ5bH07M10116	rogid:P0XRQOCYb/CdvJW7dt9XOvxDJ4Y10116	rigid:3wclwrjZRvafcOruQOYnegkn54c	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q5XIE8	uniprotkb:P31721	intact:EBI-15348306|ensembl:ENSRNOP00000023037	intact:EBI-26437724	psi-mi:itm2b_rat(display_long)|uniprotkb:Itm2b(gene name)|psi-mi:Itm2b(display_short)|uniprotkb:Immature BRI2(gene name synonym)|uniprotkb:Transmembrane protein BRI(gene name synonym)	psi-mi:c1qb_rat(display_long)|uniprotkb:C1qb(gene name)|psi-mi:C1qb(display_short)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Martins et al. (2018)	imex:IM-28469|pubmed:29476059	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26439741|imex:IM-28469-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSRNOG00000016271(gene)|ensembl:ENSRNOT00000023037(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001540"(amyloid-beta binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0010008"(endosome membrane)|go:"GO:0030660"(Golgi-associated vesicle membrane)|go:"GO:0031301"(integral component of organelle membrane)|go:"GO:0042985"(negative regulation of amyloid precursor protein biosynthetic process)|interpro:IPR007084(BRICHOS)|interpro:IPR040145|mint:Q5XIE8|refseq:NP_001006964.1|rgd:620727	go:"GO:0005581"(collagen trimer)|go:"GO:0005602"(complement component C1 complex)|go:"GO:0006955"(immune response)|go:"GO:0006958"(complement activation, classical pathway)|go:"GO:0007420"(brain development)|go:"GO:0007568"(aging)|go:"GO:0010033"(response to organic substance)|go:"GO:0042802"(identical protein binding)|go:"GO:0045087"(innate immune response)|go:"GO:0045202"(synapse)|go:"GO:0048839"(inner ear development)|go:"GO:0051384"(response to glucocorticoid)|go:"GO:0098794"(postsynapse)|go:"GO:0098883"(synapse pruning)|reactome:R-RNO-166663|reactome:R-RNO-173623|reactome:R-RNO-977606|mint:P31721|refseq:NP_062135.1|interpro:IPR001073(Complement C1q protein)|interpro:IPR008160(Collagen triple helix repeat)|interpro:IPR037573|interpro:IPR008983(Tumour necrosis factor-like)|rgd:2229	-	-	-	figure legend:st1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10116(rat-brain-cortex)|taxid:10116(Rattus norvegicus brain cortex)	-	2020/10/30	2020/10/30	rogid:DtE+ZXAZKdCMvUW5K+jXQ5bH07M10116	rogid:2+DKSXCWFTd8r4uTtwJf8hdJqMQ10116	rigid:3wclwrjZRvafcOruQOYnegkn54c	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q5XIE8	uniprotkb:P45592	intact:EBI-15348306|ensembl:ENSRNOP00000023037	intact:EBI-917556|ensembl:ENSRNOP00000059624	psi-mi:itm2b_rat(display_long)|uniprotkb:Itm2b(gene name)|psi-mi:Itm2b(display_short)|uniprotkb:Immature BRI2(gene name synonym)|uniprotkb:Transmembrane protein BRI(gene name synonym)	psi-mi:cof1_rat(display_long)|uniprotkb:Cofilin, non-muscle isoform(gene name synonym)|uniprotkb:Cfl1(gene name)|psi-mi:Cfl1(display_short)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Martins et al. (2018)	imex:IM-28469|pubmed:29476059	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26439741|imex:IM-28469-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSRNOG00000016271(gene)|ensembl:ENSRNOT00000023037(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001540"(amyloid-beta binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0010008"(endosome membrane)|go:"GO:0030660"(Golgi-associated vesicle membrane)|go:"GO:0031301"(integral component of organelle membrane)|go:"GO:0042985"(negative regulation of amyloid precursor protein biosynthetic process)|interpro:IPR007084(BRICHOS)|interpro:IPR040145|mint:Q5XIE8|refseq:NP_001006964.1|rgd:620727	rgd:69285|refseq:NP_058843.1|ensembl:ENSRNOG00000020660(gene)|ensembl:ENSRNOT00000015962(transcript)|go:"GO:0000281"(mitotic cytokinesis)|go:"GO:0001755"(neural crest cell migration)|go:"GO:0001842"(neural fold formation)|go:"GO:0003779"(actin binding)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005925"(focal adhesion)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0007010"(cytoskeleton organization)|go:"GO:0007015"(actin filament organization)|go:"GO:0007162"(negative regulation of cell adhesion)|go:"GO:0009615"(response to virus)|go:"GO:0010592"(positive regulation of lamellipodium assembly)|go:"GO:0010593"(negative regulation of lamellipodium assembly)|go:"GO:0014070"(response to organic cyclic compound)|go:"GO:0014823"(response to activity)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0016363"(nuclear matrix)|go:"GO:0019903"(protein phosphatase binding)|go:"GO:0021766"(hippocampus development)|go:"GO:0022604"(regulation of cell morphogenesis)|go:"GO:0030010"(establishment of cell polarity)|go:"GO:0030027"(lamellipodium)|go:"GO:0030030"(cell projection organization)|go:"GO:0030042"(actin filament depolymerization)|go:"GO:0030043"(actin filament fragmentation)|go:"GO:0030175"(filopodium)|go:"GO:0030307"(positive regulation of cell growth)|go:"GO:0030426"(growth cone)|go:"GO:0030835"(negative regulation of actin filament depolymerization)|go:"GO:0030836"(positive regulation of actin filament depolymerization)|go:"GO:0030864"(cortical actin cytoskeleton)|go:"GO:0031252"(cell leading edge)|go:"GO:0031258"(lamellipodium membrane)|go:"GO:0031915"(positive regulation of synaptic plasticity)|go:"GO:0031966"(mitochondrial membrane)|go:"GO:0032232"(negative regulation of actin filament bundle assembly)|go:"GO:0032587"(ruffle membrane)|go:"GO:0040019"(positive regulation of embryonic development)|go:"GO:0043005"(neuron projection)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043197"(dendritic spine)|go:"GO:0043200"(response to amino acid)|go:"GO:0044794"(positive regulation by host of viral process)|go:"GO:0045792"(negative regulation of cell size)|go:"GO:0045862"(positive regulation of proteolysis)|go:"GO:0048870"(cell motility)|go:"GO:0051014"(actin filament severing)|go:"GO:0051015"(actin filament binding)|go:"GO:0051293"(establishment of spindle localization)|go:"GO:0051511"(negative regulation of unidimensional cell growth)|go:"GO:0051894"(positive regulation of focal adhesion assembly)|go:"GO:0060999"(positive regulation of dendritic spine development)|go:"GO:0061001"(regulation of dendritic spine morphogenesis)|go:"GO:0070301"(cellular response to hydrogen peroxide)|go:"GO:0071347"(cellular response to interleukin-1)|go:"GO:0071354"(cellular response to interleukin-6)|go:"GO:0071356"(cellular response to tumor necrosis factor)|go:"GO:0071362"(cellular response to ether)|go:"GO:0071364"(cellular response to epidermal growth factor stimulus)|go:"GO:0090732"(cofilin-actin rod)|go:"GO:0097060"(synaptic membrane)|go:"GO:0098885"(modification of postsynaptic actin cytoskeleton)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:1902936"(phosphatidylinositol bisphosphate binding)|go:"GO:1902951"(negative regulation of dendritic spine maintenance)|go:"GO:1904783"(positive regulation of NMDA glutamate receptor activity)|go:"GO:1905873"(positive regulation of protein localization to cell leading edge)|go:"GO:1905875"(negative regulation of postsynaptic density organization)|go:"GO:1990314"(cellular response to insulin-like growth factor stimulus)|go:"GO:2000146"(negative regulation of cell motility)|go:"GO:2000147"(positive regulation of cell motility)|go:"GO:2000784"(positive regulation of establishment of cell polarity regulating cell shape)|go:"GO:2000814"(positive regulation of barbed-end actin filament capping)|interpro:IPR002108(Actin-binding, cofilin/tropomyosin type)|interpro:IPR017904|interpro:IPR027234|interpro:IPR029006|mint:P45592	-	-	-	figure legend:st1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10116(rat-brain-cortex)|taxid:10116(Rattus norvegicus brain cortex)	-	2020/10/30	2020/10/30	rogid:DtE+ZXAZKdCMvUW5K+jXQ5bH07M10116	rogid:xwFEqVHm0stGEHpMoijBFH/LwPY10116	rigid:3wclwrjZRvafcOruQOYnegkn54c	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q5XIE8	uniprotkb:P40241	intact:EBI-15348306|ensembl:ENSRNOP00000023037	intact:EBI-26437684|ensembl:ENSRNOP00000026633	psi-mi:itm2b_rat(display_long)|uniprotkb:Itm2b(gene name)|psi-mi:Itm2b(display_short)|uniprotkb:Immature BRI2(gene name synonym)|uniprotkb:Transmembrane protein BRI(gene name synonym)	psi-mi:cd9_rat(display_long)|uniprotkb:Cd9(gene name)|psi-mi:Cd9(display_short)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Martins et al. (2018)	imex:IM-28469|pubmed:29476059	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26439741|imex:IM-28469-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSRNOG00000016271(gene)|ensembl:ENSRNOT00000023037(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001540"(amyloid-beta binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0010008"(endosome membrane)|go:"GO:0030660"(Golgi-associated vesicle membrane)|go:"GO:0031301"(integral component of organelle membrane)|go:"GO:0042985"(negative regulation of amyloid precursor protein biosynthetic process)|interpro:IPR007084(BRICHOS)|interpro:IPR040145|mint:Q5XIE8|refseq:NP_001006964.1|rgd:620727	reactome:R-RNO-1300645|ensembl:ENSRNOG00000019556(gene)|ensembl:ENSRNOT00000026633(transcript)|go:"GO:0005178"(integrin binding)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0007338"(single fertilization)|go:"GO:0007342"(fusion of sperm to egg plasma membrane involved in single fertilization)|go:"GO:0007420"(brain development)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0008347"(glial cell migration)|go:"GO:0009414"(response to water deprivation)|go:"GO:0009897"(external side of plasma membrane)|go:"GO:0009986"(cell surface)|go:"GO:0014003"(oligodendrocyte development)|go:"GO:0014905"(myoblast fusion involved in skeletal muscle regeneration)|go:"GO:0016020"(membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0030913"(paranodal junction assembly)|go:"GO:0031623"(receptor internalization)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035036"(sperm-egg recognition)|go:"GO:0051271"(negative regulation of cellular component movement)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071404"(cellular response to low-density lipoprotein particle stimulus)|go:"GO:0090331"(negative regulation of platelet aggregation)|go:"GO:1905521"(regulation of macrophage migration)|interpro:IPR000301(CD9/CD37/CD63 antigen)|interpro:IPR008952(Tetraspanin)|interpro:IPR018499|interpro:IPR018503|interpro:IPR042055|mint:P40241|reactome:R-RNO-114608|go:"GO:0007155"(cell adhesion)|refseq:NP_444177.1|rgd:2318	-	-	-	figure legend:st1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10116(rat-brain-cortex)|taxid:10116(Rattus norvegicus brain cortex)	-	2020/10/30	2020/10/30	rogid:DtE+ZXAZKdCMvUW5K+jXQ5bH07M10116	rogid:UagE7Mr3lqoy8A7VYuUSd+UezKc10116	rigid:3wclwrjZRvafcOruQOYnegkn54c	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q5XIE8	uniprotkb:P19139	intact:EBI-15348306|ensembl:ENSRNOP00000023037	intact:EBI-1373494|uniprotkb:Q5BKC1|ensembl:ENSRNOP00000007558	psi-mi:itm2b_rat(display_long)|uniprotkb:Itm2b(gene name)|psi-mi:Itm2b(display_short)|uniprotkb:Immature BRI2(gene name synonym)|uniprotkb:Transmembrane protein BRI(gene name synonym)	psi-mi:csk21_rat(display_long)|uniprotkb:Csnk2a1(gene name)|psi-mi:Csnk2a1(display_short)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Martins et al. (2018)	imex:IM-28469|pubmed:29476059	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26439741|imex:IM-28469-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSRNOG00000016271(gene)|ensembl:ENSRNOT00000023037(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001540"(amyloid-beta binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0010008"(endosome membrane)|go:"GO:0030660"(Golgi-associated vesicle membrane)|go:"GO:0031301"(integral component of organelle membrane)|go:"GO:0042985"(negative regulation of amyloid precursor protein biosynthetic process)|interpro:IPR007084(BRICHOS)|interpro:IPR040145|mint:Q5XIE8|refseq:NP_001006964.1|rgd:620727	rgd:621663|refseq:NP_446276.1|refseq:XP_006235282.1|refseq:XP_006235283.1|reactome:R-RNO-6804756|reactome:R-RNO-6814122|reactome:R-RNO-8934903|reactome:R-RNO-8939243|reactome:R-RNO-8948751|ensembl:ENSRNOG00000005276(gene)|ensembl:ENSRNOT00000007558(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005956"(protein kinase CK2 complex)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0006915"(apoptotic process)|go:"GO:0007049"(cell cycle)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0016301"(kinase activity)|go:"GO:0016580"(Sin3 complex)|go:"GO:0016581"(NuRD complex)|go:"GO:0018105"(peptidyl-serine phosphorylation)|go:"GO:0018107"(peptidyl-threonine phosphorylation)|go:"GO:0019888"(protein phosphatase regulator activity)|go:"GO:0021987"(cerebral cortex development)|go:"GO:0030177"(positive regulation of Wnt signaling pathway)|go:"GO:0030307"(positive regulation of cell growth)|go:"GO:0033574"(response to testosterone)|go:"GO:0042802"(identical protein binding)|go:"GO:0043021"(ribonucleoprotein complex binding)|go:"GO:0043154"(negative regulation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0045732"(positive regulation of protein catabolic process)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0047485"(protein N-terminus binding)|go:"GO:0048511"(rhythmic process)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0097421"(liver regeneration)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:1903076"(regulation of protein localization to plasma membrane)|go:"GO:1905818"(regulation of chromosome separation)|go:"GO:2000059"(negative regulation of ubiquitin-dependent protein catabolic process)|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|mint:P19139|rcsb pdb:2R7I|reactome:R-RNO-1483191|reactome:R-RNO-201688|reactome:R-RNO-2514853|reactome:R-RNO-445144	-	-	-	figure legend:st1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10116(rat-brain-cortex)|taxid:10116(Rattus norvegicus brain cortex)	-	2020/10/30	2020/10/30	rogid:DtE+ZXAZKdCMvUW5K+jXQ5bH07M10116	rogid:igJEbVxBh30nMZF6jfiISzpHEMQ10116	rigid:3wclwrjZRvafcOruQOYnegkn54c	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q5XIE8	uniprotkb:Q9ESS6	intact:EBI-15348306|ensembl:ENSRNOP00000023037	intact:EBI-26437661|ensembl:ENSRNOP00000047809	psi-mi:itm2b_rat(display_long)|uniprotkb:Itm2b(gene name)|psi-mi:Itm2b(display_short)|uniprotkb:Immature BRI2(gene name synonym)|uniprotkb:Transmembrane protein BRI(gene name synonym)	psi-mi:bcam_rat(display_long)|uniprotkb:Bcam(gene name)|psi-mi:Bcam(display_short)|uniprotkb:Lu(gene name synonym)|uniprotkb:B-CAM cell surface glycoprotein(gene name synonym)|uniprotkb:Lutheran antigen(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Martins et al. (2018)	imex:IM-28469|pubmed:29476059	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26439741|imex:IM-28469-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSRNOG00000016271(gene)|ensembl:ENSRNOT00000023037(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001540"(amyloid-beta binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0010008"(endosome membrane)|go:"GO:0030660"(Golgi-associated vesicle membrane)|go:"GO:0031301"(integral component of organelle membrane)|go:"GO:0042985"(negative regulation of amyloid precursor protein biosynthetic process)|interpro:IPR007084(BRICHOS)|interpro:IPR040145|mint:Q5XIE8|refseq:NP_001006964.1|rgd:620727	ensembl:ENSRNOG00000029399(gene)|ensembl:ENSRNOT00000045574(transcript)|go:"GO:0005055"(laminin receptor activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0007155"(cell adhesion)|go:"GO:0007160"(cell-matrix adhesion)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0009986"(cell surface)|go:"GO:0016021"(integral component of membrane)|go:"GO:0043236"(laminin binding)|interpro:IPR003598(Immunoglobulin subtype 2)|interpro:IPR003599(Immunoglobulin subtype)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR013162(CD80-like, immunoglobulin C2-set)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR036179|mint:Q9ESS6|refseq:NP_113940.1|rgd:68378	-	-	-	figure legend:st1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10116(rat-brain-cortex)|taxid:10116(Rattus norvegicus brain cortex)	-	2020/10/30	2020/10/30	rogid:DtE+ZXAZKdCMvUW5K+jXQ5bH07M10116	rogid:gXifukdZ+aemcGCwqz/Q8qlsqBo10116	rigid:3wclwrjZRvafcOruQOYnegkn54c	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q5XIE8	uniprotkb:Q9WTP0	intact:EBI-15348306|ensembl:ENSRNOP00000023037	intact:EBI-11169976|uniprotkb:Q9WTP1	psi-mi:itm2b_rat(display_long)|uniprotkb:Itm2b(gene name)|psi-mi:Itm2b(display_short)|uniprotkb:Immature BRI2(gene name synonym)|uniprotkb:Transmembrane protein BRI(gene name synonym)	psi-mi:e41l1_rat(display_long)|uniprotkb:Epb41l1(gene name)|psi-mi:Epb41l1(display_short)|uniprotkb:Epb4.1l1(gene name synonym)|uniprotkb:Neuronal protein 4.1(gene name synonym)|uniprotkb:Erythrocyte membrane protein band 4.1-like 1(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Martins et al. (2018)	imex:IM-28469|pubmed:29476059	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26439741|imex:IM-28469-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSRNOG00000016271(gene)|ensembl:ENSRNOT00000023037(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001540"(amyloid-beta binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0010008"(endosome membrane)|go:"GO:0030660"(Golgi-associated vesicle membrane)|go:"GO:0031301"(integral component of organelle membrane)|go:"GO:0042985"(negative regulation of amyloid precursor protein biosynthetic process)|interpro:IPR007084(BRICHOS)|interpro:IPR040145|mint:Q5XIE8|refseq:NP_001006964.1|rgd:620727	refseq:NP_742087.1|interpro:IPR008379(Band 4.1, C-terminal)|interpro:IPR019749|interpro:IPR000798(Ezrin/radixin/moesin ERM)|interpro:IPR014847("FERM adjacent (FA)")|interpro:IPR014352(FERM/acyl-CoA-binding protein, 3-helical bundle)|interpro:IPR019748|interpro:IPR019747|interpro:IPR000299(Band 4.1, N-terminal)|interpro:IPR018979|interpro:IPR018980|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR007477(SAB)|interpro:IPR029071|rgd:71087|go:"GO:0003779"(actin binding)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005886"(plasma membrane)|go:"GO:0014069"(postsynaptic density)|go:"GO:0030866"(cortical actin cytoskeleton organization)|go:"GO:0031032"(actomyosin structure organization)|go:"GO:0032991"(protein-containing complex)|go:"GO:0097060"(synaptic membrane)|reactome:R-RNO-399719|reactome:R-RNO-6794361|mint:Q9WTP0|interpro:IPR035963	-	-	-	figure legend:st1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10116(rat-brain-cortex)|taxid:10116(Rattus norvegicus brain cortex)	-	2020/10/30	2020/10/30	rogid:DtE+ZXAZKdCMvUW5K+jXQ5bH07M10116	rogid:UEt+cCxW/3aDNyIqQUHiCHjI4K410116	rigid:3wclwrjZRvafcOruQOYnegkn54c	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q5XIE8	uniprotkb:Q06647	intact:EBI-15348306|ensembl:ENSRNOP00000023037	intact:EBI-918179|ensembl:ENSRNOP00000002732	psi-mi:itm2b_rat(display_long)|uniprotkb:Itm2b(gene name)|psi-mi:Itm2b(display_short)|uniprotkb:Immature BRI2(gene name synonym)|uniprotkb:Transmembrane protein BRI(gene name synonym)	psi-mi:atpo_rat(display_long)|uniprotkb:Atp5po(gene name)|psi-mi:Atp5po(display_short)|uniprotkb:ATP synthase peripheral stalk subunit OSCP(gene name synonym)|uniprotkb:Atp5o(gene name synonym)|uniprotkb:Oligomycin sensitivity conferral protein(gene name synonym)|uniprotkb:Sperm flagella protein 4(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Martins et al. (2018)	imex:IM-28469|pubmed:29476059	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26439741|imex:IM-28469-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSRNOG00000016271(gene)|ensembl:ENSRNOT00000023037(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001540"(amyloid-beta binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0010008"(endosome membrane)|go:"GO:0030660"(Golgi-associated vesicle membrane)|go:"GO:0031301"(integral component of organelle membrane)|go:"GO:0042985"(negative regulation of amyloid precursor protein biosynthetic process)|interpro:IPR007084(BRICHOS)|interpro:IPR040145|mint:Q5XIE8|refseq:NP_001006964.1|rgd:620727	rgd:621379|refseq:NP_620238.1|ensembl:ENSRNOG00000001991(gene)|ensembl:ENSRNOT00000002732(transcript)|go:"GO:0000274"(mitochondrial proton-transporting ATP synthase, stator stalk)|go:"GO:0000276"("mitochondrial proton-transporting ATP synthase complex, coupling factor F(o)")|go:"GO:0005739"(mitochondrion)|go:"GO:0005753"(mitochondrial proton-transporting ATP synthase complex)|go:"GO:0005886"(plasma membrane)|go:"GO:0006754"(ATP biosynthetic process)|go:"GO:0009986"(cell surface)|go:"GO:0015986"(ATP synthesis coupled proton transport)|go:"GO:0042776"(mitochondrial ATP synthesis coupled proton transport)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045261"("proton-transporting ATP synthase complex, catalytic core F(1)")|go:"GO:0046034"(ATP metabolic process)|go:"GO:0046933"(proton-transporting ATP synthase activity, rotational mechanism)|go:"GO:0071320"(cellular response to cAMP)|go:"GO:0071345"(cellular response to cytokine stimulus)|go:"GO:1903924"(estradiol binding)|interpro:IPR000711(ATPase, F1 complex, OSCP/delta subunit)|interpro:IPR020781|interpro:IPR026015|mint:Q06647|reactome:R-RNO-163210|reactome:R-RNO-8949613	-	-	-	figure legend:st1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10116(rat-brain-cortex)|taxid:10116(Rattus norvegicus brain cortex)	-	2020/10/30	2020/10/30	rogid:DtE+ZXAZKdCMvUW5K+jXQ5bH07M10116	rogid:F/PihaxUf1uclL8LOwKpSse+dCA10116	rigid:3wclwrjZRvafcOruQOYnegkn54c	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q5XIE8	uniprotkb:P35435	intact:EBI-15348306|ensembl:ENSRNOP00000023037	intact:EBI-917355	psi-mi:itm2b_rat(display_long)|uniprotkb:Itm2b(gene name)|psi-mi:Itm2b(display_short)|uniprotkb:Immature BRI2(gene name synonym)|uniprotkb:Transmembrane protein BRI(gene name synonym)	psi-mi:atpg_rat(display_long)|uniprotkb:Atp5f1c(gene name)|psi-mi:Atp5f1c(display_short)|uniprotkb:ATP synthase F1 subunit gamma(gene name synonym)|uniprotkb:Atp5c(gene name synonym)|uniprotkb:Atp5c1(gene name synonym)|uniprotkb:F-ATPase gamma subunit(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Martins et al. (2018)	imex:IM-28469|pubmed:29476059	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26439741|imex:IM-28469-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSRNOG00000016271(gene)|ensembl:ENSRNOT00000023037(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001540"(amyloid-beta binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0010008"(endosome membrane)|go:"GO:0030660"(Golgi-associated vesicle membrane)|go:"GO:0031301"(integral component of organelle membrane)|go:"GO:0042985"(negative regulation of amyloid precursor protein biosynthetic process)|interpro:IPR007084(BRICHOS)|interpro:IPR040145|mint:Q5XIE8|refseq:NP_001006964.1|rgd:620727	rgd:620011|interpro:IPR000131(ATPase, F1 complex, gamma subunit)|interpro:IPR023632|mint:P35435|interpro:IPR035968|go:"GO:0000275"("mitochondrial proton-transporting ATP synthase complex, catalytic sector F(1)")|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005753"(mitochondrial proton-transporting ATP synthase complex)|go:"GO:0015986"(ATP synthesis coupled proton transport)|go:"GO:0042776"(mitochondrial ATP synthesis coupled proton transport)|go:"GO:0045261"("proton-transporting ATP synthase complex, catalytic core F(1)")|go:"GO:0046034"(ATP metabolic process)|go:"GO:0046933"(proton-transporting ATP synthase activity, rotational mechanism)|go:"GO:0071732"(cellular response to nitric oxide)|rcsb pdb:1MAB|rcsb pdb:2F43|reactome:R-RNO-163210|reactome:R-RNO-8949613	-	-	-	figure legend:st1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10116(rat-brain-cortex)|taxid:10116(Rattus norvegicus brain cortex)	-	2020/10/30	2020/10/30	rogid:DtE+ZXAZKdCMvUW5K+jXQ5bH07M10116	rogid:py9RCXV2/aoMy8UslZteKeJAdak10116	rigid:3wclwrjZRvafcOruQOYnegkn54c	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q5XIE8	uniprotkb:P18484	intact:EBI-15348306|ensembl:ENSRNOP00000023037	intact:EBI-539360	psi-mi:itm2b_rat(display_long)|uniprotkb:Itm2b(gene name)|psi-mi:Itm2b(display_short)|uniprotkb:Immature BRI2(gene name synonym)|uniprotkb:Transmembrane protein BRI(gene name synonym)	psi-mi:ap2a2_rat(display_long)|uniprotkb:Adaptor protein complex AP-2 subunit alpha-2(gene name synonym)|uniprotkb:Alpha2-adaptin(gene name synonym)|uniprotkb:Plasma membrane adaptor HA2/AP2 adaptin alpha C subunit(gene name synonym)|uniprotkb:Alpha-adaptin C(gene name synonym)|uniprotkb:Clathrin assembly protein complex 2 alpha-C large chain(gene name synonym)|uniprotkb:100 kDa coated vesicle protein C(gene name synonym)|uniprotkb:Ap2a2(gene name)|psi-mi:Ap2a2(display_short)|uniprotkb:Adtab(gene name synonym)|uniprotkb:Adaptor-related protein complex 2 subunit alpha-2(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Martins et al. (2018)	imex:IM-28469|pubmed:29476059	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26439741|imex:IM-28469-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSRNOG00000016271(gene)|ensembl:ENSRNOT00000023037(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001540"(amyloid-beta binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0010008"(endosome membrane)|go:"GO:0030660"(Golgi-associated vesicle membrane)|go:"GO:0031301"(integral component of organelle membrane)|go:"GO:0042985"(negative regulation of amyloid precursor protein biosynthetic process)|interpro:IPR007084(BRICHOS)|interpro:IPR040145|mint:Q5XIE8|refseq:NP_001006964.1|rgd:620727	rgd:71015|go:"GO:0005886"(plasma membrane)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006898"(receptor-mediated endocytosis)|interpro:IPR002553(Clathrin/coatomer adaptor, adaptin-like, N-terminal)|interpro:IPR003164(Clathrin adaptor, alpha-adaptin, appendage, C-terminal subdomain)|interpro:IPR008152(Clathrin adaptor, alpha/beta/gamma-adaptin, appendage, Ig-like subdomain)|interpro:IPR009028(Clathrin/coatomer adaptor, adaptin-like, appendage, C-terminal subdomain)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR012295(Beta2-adaptin/TATA-box binding, C-terminal)|interpro:IPR013041(Clathrin/coatomer adaptor, adaptin-like, appendage, Ig-like subdomain)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR017104(Adaptor protein complex AP-2, alpha subunit)|rcsb pdb:2VGL|rcsb pdb:2XA7|go:"GO:0008021"(synaptic vesicle)|rcsb pdb:4NEE|rcsb pdb:4UQI|rcsb pdb:6OWT|rcsb pdb:6QH5|rcsb pdb:6QH6|rcsb pdb:6QH7|go:"GO:0019900"(kinase binding)|rcsb pdb:6URI|rcsb pdb:6YAE|rcsb pdb:6YAF|rcsb pdb:6YAH|reactome:R-RNO-177504|reactome:R-RNO-2132295|reactome:R-RNO-416993|reactome:R-RNO-437239|reactome:R-RNO-5099900|reactome:R-RNO-5140745|reactome:R-RNO-6798695|reactome:R-RNO-8856825|go:"GO:0019901"(protein kinase binding)|reactome:R-RNO-8856828|go:"GO:0019904"(protein domain specific binding)|reactome:R-RNO-8866427|reactome:R-RNO-8964038|go:"GO:0030117"(membrane coat)|go:"GO:0030122"(AP-2 adaptor complex)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0035091"(phosphatidylinositol binding)|go:"GO:0035615"(clathrin adaptor activity)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0072583"(clathrin-dependent endocytosis)|go:"GO:0097718"(disordered domain specific binding)|go:"GO:0140312"(cargo adaptor activity)|mint:P18484|dip:DIP-29765N	-	-	-	figure legend:st1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10116(rat-brain-cortex)|taxid:10116(Rattus norvegicus brain cortex)	-	2020/10/30	2020/10/30	rogid:DtE+ZXAZKdCMvUW5K+jXQ5bH07M10116	rogid:/3UaX0n3j6Lo0w7GMn0uWzL5GI010116	rigid:3wclwrjZRvafcOruQOYnegkn54c	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q5XIE8	uniprotkb:O70511	intact:EBI-15348306|ensembl:ENSRNOP00000023037	intact:EBI-9663355|uniprotkb:Q574D7|uniprotkb:Q574D8|uniprotkb:Q574D9|uniprotkb:Q574E0|uniprotkb:Q574E2|uniprotkb:Q8VDA0	psi-mi:itm2b_rat(display_long)|uniprotkb:Itm2b(gene name)|psi-mi:Itm2b(display_short)|uniprotkb:Immature BRI2(gene name synonym)|uniprotkb:Transmembrane protein BRI(gene name synonym)	psi-mi:ank3_rat(display_long)|uniprotkb:Ank3(gene name)|psi-mi:Ank3(display_short)|uniprotkb:Ankyrin-G(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Martins et al. (2018)	imex:IM-28469|pubmed:29476059	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26439741|imex:IM-28469-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSRNOG00000016271(gene)|ensembl:ENSRNOT00000023037(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001540"(amyloid-beta binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0010008"(endosome membrane)|go:"GO:0030660"(Golgi-associated vesicle membrane)|go:"GO:0031301"(integral component of organelle membrane)|go:"GO:0042985"(negative regulation of amyloid precursor protein biosynthetic process)|interpro:IPR007084(BRICHOS)|interpro:IPR040145|mint:Q5XIE8|refseq:NP_001006964.1|rgd:620727	mint:O70511|rgd:620157|refseq:NP_001029156.1|refseq:NP_113993.1|dip:DIP-60342N|go:"GO:0000281"(mitotic cytokinesis)|go:"GO:0005200"(structural constituent of cytoskeleton)|go:"GO:0005764"(lysosome)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005886"(plasma membrane)|go:"GO:0007009"(plasma membrane organization)|go:"GO:0007165"(signal transduction)|go:"GO:0007409"(axonogenesis)|go:"GO:0007411"(axon guidance)|go:"GO:0007528"(neuromuscular junction development)|go:"GO:0008092"(cytoskeletal protein binding)|go:"GO:0009925"(basal plasma membrane)|go:"GO:0009986"(cell surface)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010650"(positive regulation of cell communication by electrical coupling)|go:"GO:0010765"(positive regulation of sodium ion transport)|go:"GO:0010960"(magnesium ion homeostasis)|go:"GO:0014704"(intercalated disc)|go:"GO:0014731"(spectrin-associated cytoskeleton)|go:"GO:0016020"(membrane)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016328"(lateral plasma membrane)|go:"GO:0016529"(sarcoplasmic reticulum)|go:"GO:0019228"(neuronal action potential)|go:"GO:0030018"(Z disc)|go:"GO:0030315"(T-tubule)|go:"GO:0030424"(axon)|go:"GO:0030425"(dendrite)|go:"GO:0030507"(spectrin binding)|go:"GO:0030674"(protein-macromolecule adaptor activity)|go:"GO:0031594"(neuromuscular junction)|go:"GO:0033268"(node of Ranvier)|go:"GO:0033270"(paranode region of axon)|go:"GO:0034112"(positive regulation of homotypic cell-cell adhesion)|go:"GO:0042383"(sarcolemma)|go:"GO:0043001"(Golgi to plasma membrane protein transport)|go:"GO:0043005"(neuron projection)|go:"GO:0043034"(costamere)|go:"GO:0043266"(regulation of potassium ion transport)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0045162"(clustering of voltage-gated sodium channels)|go:"GO:0045184"(establishment of protein localization)|go:"GO:0045202"(synapse)|go:"GO:0045211"(postsynaptic membrane)|go:"GO:0045296"(cadherin binding)|go:"GO:0045838"(positive regulation of membrane potential)|go:"GO:0050808"(synapse organization)|go:"GO:0071286"(cellular response to magnesium ion)|go:"GO:0071709"(membrane assembly)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0072660"(maintenance of protein location in plasma membrane)|go:"GO:0090314"(positive regulation of protein targeting to membrane)|go:"GO:0099612"(protein localization to axon)|go:"GO:0140031"(phosphorylation-dependent protein binding)|go:"GO:1900827"(positive regulation of membrane depolarization during cardiac muscle cell action potential)|go:"GO:1902260"(negative regulation of delayed rectifier potassium channel activity)|go:"GO:2000651"(positive regulation of sodium ion transmembrane transporter activity)|go:"GO:2001259"(positive regulation of cation channel activity)|interpro:IPR000488(Death)|interpro:IPR000906(ZU5)|interpro:IPR002110(Ankyrin)|interpro:IPR011029(DEATH-like)|interpro:IPR020683|interpro:IPR036770|interpro:IPR037971|interpro:IPR040745|rcsb pdb:5YIP|rcsb pdb:5YIQ|rcsb pdb:6A9X|rcsb pdb:6M3P|rcsb pdb:6M3R|go:"GO:0043194"(axon initial segment)	-	-	-	figure legend:st1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10116(rat-brain-cortex)|taxid:10116(Rattus norvegicus brain cortex)	-	2020/10/30	2020/10/30	rogid:DtE+ZXAZKdCMvUW5K+jXQ5bH07M10116	rogid:FloqiVqbDqo4HEvTwKuGl7Q0Cxw10116	rigid:3wclwrjZRvafcOruQOYnegkn54c	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q5XIE8	uniprotkb:O08838	intact:EBI-15348306|ensembl:ENSRNOP00000023037	intact:EBI-80080	psi-mi:itm2b_rat(display_long)|uniprotkb:Itm2b(gene name)|psi-mi:Itm2b(display_short)|uniprotkb:Immature BRI2(gene name synonym)|uniprotkb:Transmembrane protein BRI(gene name synonym)	psi-mi:amph_rat(display_long)|uniprotkb:Amph(gene name)|psi-mi:Amph(display_short)|uniprotkb:Amph1(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Martins et al. (2018)	imex:IM-28469|pubmed:29476059	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26439741|imex:IM-28469-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSRNOG00000016271(gene)|ensembl:ENSRNOT00000023037(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001540"(amyloid-beta binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0010008"(endosome membrane)|go:"GO:0030660"(Golgi-associated vesicle membrane)|go:"GO:0031301"(integral component of organelle membrane)|go:"GO:0042985"(negative regulation of amyloid precursor protein biosynthetic process)|interpro:IPR007084(BRICHOS)|interpro:IPR040145|mint:Q5XIE8|refseq:NP_001006964.1|rgd:620727	go:"GO:0045807"(positive regulation of endocytosis)|go:"GO:0048488"(synaptic vesicle endocytosis)|go:"GO:0005543"(phospholipid binding)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005886"(plasma membrane)|go:"GO:0007612"(learning)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0031256"(leading edge membrane)|go:"GO:0043195"(terminal bouton)|go:"GO:0043547"(positive regulation of GTPase activity)|go:"GO:0043679"(axon terminus)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0098684"(photoreceptor ribbon synapse)|go:"GO:0098793"(presynapse)|go:"GO:0098833"(presynaptic endocytic zone)|go:"GO:0098850"(extrinsic component of synaptic vesicle membrane)|go:"GO:0098978"(glutamatergic synapse)|interpro:IPR001452(Src homology-3)|interpro:IPR003005(Amphiphysin)|interpro:IPR003017(Amphiphysin, isoform 1)|interpro:IPR004148(BAR)|interpro:IPR027267|interpro:IPR035470|interpro:IPR036028|rcsb pdb:2VJ0|rcsb pdb:5M5T|reactome:R-RNO-8856828|rgd:620274|refseq:NP_071553.1|mint:O08838|dip:DIP-30977N	-	-	-	figure legend:st1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10116(rat-brain-cortex)|taxid:10116(Rattus norvegicus brain cortex)	-	2020/10/30	2020/10/30	rogid:DtE+ZXAZKdCMvUW5K+jXQ5bH07M10116	rogid:wTANhsy4BxCZYbSIhwlrr+m9Tt810116	rigid:3wclwrjZRvafcOruQOYnegkn54c	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q5XIE8	uniprotkb:P23565	intact:EBI-15348306|ensembl:ENSRNOP00000023037	intact:EBI-6899875	psi-mi:itm2b_rat(display_long)|uniprotkb:Itm2b(gene name)|psi-mi:Itm2b(display_short)|uniprotkb:Immature BRI2(gene name synonym)|uniprotkb:Transmembrane protein BRI(gene name synonym)	psi-mi:ainx_rat(display_long)|uniprotkb:Ina(gene name)|psi-mi:Ina(display_short)|uniprotkb:Inexa(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Martins et al. (2018)	imex:IM-28469|pubmed:29476059	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26439741|imex:IM-28469-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSRNOG00000016271(gene)|ensembl:ENSRNOT00000023037(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001540"(amyloid-beta binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0010008"(endosome membrane)|go:"GO:0030660"(Golgi-associated vesicle membrane)|go:"GO:0031301"(integral component of organelle membrane)|go:"GO:0042985"(negative regulation of amyloid precursor protein biosynthetic process)|interpro:IPR007084(BRICHOS)|interpro:IPR040145|mint:Q5XIE8|refseq:NP_001006964.1|rgd:620727	go:"GO:0099160"(postsynaptic intermediate filament cytoskeleton)|go:"GO:0099184"(structural constituent of postsynaptic intermediate filament cytoskeleton)|go:"GO:1990830"(cellular response to leukemia inhibitory factor)|go:"GO:0005883"(neurofilament)|go:"GO:0007399"(nervous system development)|go:"GO:0030154"(cell differentiation)|go:"GO:0036464"(cytoplasmic ribonucleoprotein granule)|go:"GO:0042246"(tissue regeneration)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045104"(intermediate filament cytoskeleton organization)|go:"GO:0060052"(neurofilament cytoskeleton organization)|go:"GO:0098685"(Schaffer collateral - CA1 synapse)|go:"GO:0098794"(postsynapse)|go:"GO:0098973"(structural constituent of postsynaptic actin cytoskeleton)|go:"GO:0098978"(glutamatergic synapse)|interpro:IPR006821(Intermediate filament, DNA-binding region)|interpro:IPR018039|rgd:2911|mint:P23565|interpro:IPR027703|interpro:IPR039008	-	-	-	figure legend:st1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10116(rat-brain-cortex)|taxid:10116(Rattus norvegicus brain cortex)	-	2020/10/30	2020/10/30	rogid:DtE+ZXAZKdCMvUW5K+jXQ5bH07M10116	rogid:4qBkIm9ifAEYegj00H2EUgBCn0w10116	rigid:3wclwrjZRvafcOruQOYnegkn54c	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q5XIE8	uniprotkb:P06238	intact:EBI-15348306|ensembl:ENSRNOP00000023037	intact:EBI-15184861|ensembl:ENSRNOP00000019346|ensembl:ENSRNOP00000066130|uniprotkb:Q4FZY3	psi-mi:itm2b_rat(display_long)|uniprotkb:Itm2b(gene name)|psi-mi:Itm2b(display_short)|uniprotkb:Immature BRI2(gene name synonym)|uniprotkb:Transmembrane protein BRI(gene name synonym)	psi-mi:a2mg_rat(display_long)|uniprotkb:A2m(gene name)|psi-mi:A2m(display_short)|uniprotkb:A2m1(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Martins et al. (2018)	imex:IM-28469|pubmed:29476059	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26439741|imex:IM-28469-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSRNOG00000016271(gene)|ensembl:ENSRNOT00000023037(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001540"(amyloid-beta binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0010008"(endosome membrane)|go:"GO:0030660"(Golgi-associated vesicle membrane)|go:"GO:0031301"(integral component of organelle membrane)|go:"GO:0042985"(negative regulation of amyloid precursor protein biosynthetic process)|interpro:IPR007084(BRICHOS)|interpro:IPR040145|mint:Q5XIE8|refseq:NP_001006964.1|rgd:620727	ensembl:ENSRNOG00000028896(gene)|ensembl:ENSRNOG00000045772(gene)|ensembl:ENSRNOT00000019346(transcript)|ensembl:ENSRNOT00000075799(transcript)|go:"GO:0001553"(luteinization)|go:"GO:0001869"(negative regulation of complement activation, lectin pathway)|go:"GO:0002020"(protease binding)|go:"GO:0002438"(acute inflammatory response to antigenic stimulus)|go:"GO:0004866"(endopeptidase inhibitor activity)|go:"GO:0004867"(serine-type endopeptidase inhibitor activity)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005615"(extracellular space)|go:"GO:0006953"(acute-phase response)|go:"GO:0007584"(response to nutrient)|interpro:IPR002890(Alpha-2-macroglobulin, N-terminal)|interpro:IPR008930(Terpenoid cylases/protein prenyltransferase alpha-alpha toroid)|interpro:IPR009048(Alpha-macroglobulin, receptor-binding)|interpro:IPR011625(Alpha-2-macroglobulin, N-terminal 2)|interpro:IPR011626(A-macroglobulin complement component)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR014756(Immunoglobulin E-set)|interpro:IPR019742|interpro:IPR036595|interpro:IPR040839|interpro:IPR041555|interpro:IPR041813|mint:P06238|reactome:R-RNO-114608|reactome:R-RNO-140837|reactome:R-RNO-1474228|reactome:R-RNO-8963896|interpro:IPR001599(Alpha-2-macroglobulin)|go:"GO:0010037"(response to carbon dioxide)|go:"GO:0010951"(negative regulation of endopeptidase activity)|go:"GO:0019838"(growth factor binding)|go:"GO:0019899"(enzyme binding)|go:"GO:0019959"(interleukin-8 binding)|go:"GO:0019966"(interleukin-1 binding)|go:"GO:0034695"(response to prostaglandin E)|go:"GO:0042802"(identical protein binding)|go:"GO:0043120"(tumor necrosis factor binding)|go:"GO:0048306"(calcium-dependent protein binding)|go:"GO:0048403"(brain-derived neurotrophic factor binding)|go:"GO:0048406"(nerve growth factor binding)|go:"GO:0048863"(stem cell differentiation)|go:"GO:0051384"(response to glucocorticoid)|go:"GO:1990402"(embryonic liver development)|go:"GO:0009611"(response to wounding)|refseq:NP_036620.2|refseq:XP_003749876.1|rgd:2004	-	-	-	figure legend:st1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10116(rat-brain-cortex)|taxid:10116(Rattus norvegicus brain cortex)	-	2020/10/30	2020/10/30	rogid:DtE+ZXAZKdCMvUW5K+jXQ5bH07M10116	rogid:MAZi2KkXU2jKuLSeqwT1dNJlrY010116	rigid:3wclwrjZRvafcOruQOYnegkn54c	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q5XIE8	uniprotkb:P63269	intact:EBI-15348306|ensembl:ENSRNOP00000023037	intact:EBI-297811|uniprotkb:P12718|ensembl:ENSRNOP00000050322	psi-mi:itm2b_rat(display_long)|uniprotkb:Itm2b(gene name)|psi-mi:Itm2b(display_short)|uniprotkb:Immature BRI2(gene name synonym)|uniprotkb:Transmembrane protein BRI(gene name synonym)	psi-mi:acth_rat(display_long)|uniprotkb:Actg2(gene name)|psi-mi:Actg2(display_short)|uniprotkb:Acta3(gene name synonym)|uniprotkb:Actsg(gene name synonym)|uniprotkb:Smooth muscle gamma-actin(gene name synonym)|uniprotkb:Gamma-2-actin(gene name synonym)|uniprotkb:Alpha-actin-3(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Martins et al. (2018)	imex:IM-28469|pubmed:29476059	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26439741|imex:IM-28469-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSRNOG00000016271(gene)|ensembl:ENSRNOT00000023037(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001540"(amyloid-beta binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0010008"(endosome membrane)|go:"GO:0030660"(Golgi-associated vesicle membrane)|go:"GO:0031301"(integral component of organelle membrane)|go:"GO:0042985"(negative regulation of amyloid precursor protein biosynthetic process)|interpro:IPR007084(BRICHOS)|interpro:IPR040145|mint:Q5XIE8|refseq:NP_001006964.1|rgd:620727	ensembl:ENSRNOG00000029401(gene)|ensembl:ENSRNOT00000042699(transcript)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005869"(dynactin complex)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0014829"(vascular associated smooth muscle contraction)|go:"GO:0030027"(lamellipodium)|go:"GO:0030175"(filopodium)|go:"GO:0032982"(myosin filament)|go:"GO:0044297"(cell body)|go:"GO:0071944"(cell periphery)|go:"GO:0090131"(mesenchyme migration)|interpro:IPR004000(Actin/actin-like)|interpro:IPR004001(Actin, conserved site)|interpro:IPR020902|interpro:IPR043129|mint:P63269|reactome:R-RNO-445355|rgd:2027|refseq:NP_037025.1|refseq:XP_006236790.1	-	-	-	figure legend:st1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10116(rat-brain-cortex)|taxid:10116(Rattus norvegicus brain cortex)	-	2020/10/30	2020/10/30	rogid:DtE+ZXAZKdCMvUW5K+jXQ5bH07M10116	rogid:tp0JsXhrGsRl5i4Wg2dyaPGUPxA10116	rigid:3wclwrjZRvafcOruQOYnegkn54c	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q5XIE8	uniprotkb:P60711	intact:EBI-15348306|ensembl:ENSRNOP00000023037	intact:EBI-349272|uniprotkb:Q64316|uniprotkb:P02570|uniprotkb:P70514|uniprotkb:P99021|uniprotkb:Q11211|ensembl:ENSRNOP00000044296	psi-mi:itm2b_rat(display_long)|uniprotkb:Itm2b(gene name)|psi-mi:Itm2b(display_short)|uniprotkb:Immature BRI2(gene name synonym)|uniprotkb:Transmembrane protein BRI(gene name synonym)	psi-mi:actb_rat(display_long)|uniprotkb:Actb(gene name)|psi-mi:Actb(display_short)|uniprotkb:Beta-actin(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Martins et al. (2018)	imex:IM-28469|pubmed:29476059	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26439741|imex:IM-28469-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSRNOG00000016271(gene)|ensembl:ENSRNOT00000023037(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001540"(amyloid-beta binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0010008"(endosome membrane)|go:"GO:0030660"(Golgi-associated vesicle membrane)|go:"GO:0031301"(integral component of organelle membrane)|go:"GO:0042985"(negative regulation of amyloid precursor protein biosynthetic process)|interpro:IPR007084(BRICHOS)|interpro:IPR040145|mint:Q5XIE8|refseq:NP_001006964.1|rgd:620727	rgd:628837|refseq:NP_112406.1|ensembl:ENSRNOG00000034254(gene)|ensembl:ENSRNOT00000042459(transcript)|go:"GO:0000079"(regulation of cyclin-dependent protein serine/threonine kinase activity)|go:"GO:0001725"(stress fiber)|go:"GO:0001738"(morphogenesis of a polarized epithelium)|go:"GO:0002102"(podosome)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005884"(actin filament)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005912"(adherens junction)|go:"GO:0005925"(focal adhesion)|go:"GO:0007163"(establishment or maintenance of cell polarity)|go:"GO:0007409"(axonogenesis)|go:"GO:0007623"(circadian rhythm)|go:"GO:0009612"(response to mechanical stimulus)|go:"GO:0014069"(postsynaptic density)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0016020"(membrane)|go:"GO:0019894"(kinesin binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0022898"(regulation of transmembrane transporter activity)|go:"GO:0030027"(lamellipodium)|go:"GO:0030424"(axon)|go:"GO:0030863"(cortical cytoskeleton)|go:"GO:0030957"(Tat protein binding)|go:"GO:0032091"(negative regulation of protein binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034333"(adherens junction assembly)|go:"GO:0035902"(response to immobilization stress)|go:"GO:0036464"(cytoplasmic ribonucleoprotein granule)|go:"GO:0042802"(identical protein binding)|go:"GO:0043296"(apical junction complex)|go:"GO:0044305"(calyx of Held)|go:"GO:0045121"(membrane raft)|go:"GO:0045176"(apical protein localization)|go:"GO:0045202"(synapse)|go:"GO:0048488"(synaptic vesicle endocytosis)|go:"GO:0048870"(cell motility)|go:"GO:0050998"(nitric-oxide synthase binding)|go:"GO:0051621"(regulation of norepinephrine uptake)|go:"GO:0060041"(retina development in camera-type eye)|go:"GO:0070160"(tight junction)|go:"GO:0071257"(cellular response to electrical stimulus)|go:"GO:0071896"(protein localization to adherens junction)|go:"GO:0072749"(cellular response to cytochalasin B)|go:"GO:0097433"(dense body)|go:"GO:0098685"(Schaffer collateral - CA1 synapse)|go:"GO:0098871"(postsynaptic actin cytoskeleton)|go:"GO:0035267"(NuA4 histone acetyltransferase complex)|go:"GO:0098973"(structural constituent of postsynaptic actin cytoskeleton)|reactome:R-RNO-190873|reactome:R-RNO-196025|go:"GO:0098974"(postsynaptic actin cytoskeleton organization)|reactome:R-RNO-2029482|reactome:R-RNO-3928662|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0150111"(regulation of transepithelial transport)|reactome:R-RNO-418990|reactome:R-RNO-437239|go:"GO:1903076"(regulation of protein localization to plasma membrane)|reactome:R-RNO-4420097|reactome:R-RNO-445095|reactome:R-RNO-446353|reactome:R-RNO-5250924|reactome:R-RNO-5626467|reactome:R-RNO-5663213|reactome:R-RNO-5663220|reactome:R-RNO-5674135|reactome:R-RNO-5689603|reactome:R-RNO-5696394|reactome:R-RNO-8856828|reactome:R-RNO-9035034|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR004000(Actin/actin-like)|interpro:IPR004001(Actin, conserved site)|interpro:IPR020902|interpro:IPR043129|mint:P60711	-	-	-	figure legend:st1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10116(rat-brain-cortex)|taxid:10116(Rattus norvegicus brain cortex)	-	2020/10/30	2020/10/30	rogid:DtE+ZXAZKdCMvUW5K+jXQ5bH07M10116	rogid:Hoge1B8Pn56kvbNTpkSLsQuHwRc10116	rigid:3wclwrjZRvafcOruQOYnegkn54c	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q5XIE8	uniprotkb:P06761	intact:EBI-15348306|ensembl:ENSRNOP00000023037	intact:EBI-916036|ensembl:ENSRNOP00000025064	psi-mi:itm2b_rat(display_long)|uniprotkb:Itm2b(gene name)|psi-mi:Itm2b(display_short)|uniprotkb:Immature BRI2(gene name synonym)|uniprotkb:Transmembrane protein BRI(gene name synonym)	psi-mi:bip_rat(display_long)|uniprotkb:Hspa5(gene name)|psi-mi:Hspa5(display_short)|uniprotkb:Grp78(gene name synonym)|uniprotkb:Immunoglobulin heavy chain-binding protein(gene name synonym)|uniprotkb:Steroidogenesis-activator polypeptide(gene name synonym)|uniprotkb:78 kDa glucose-regulated protein(gene name synonym)|uniprotkb:Binding-immunoglobulin protein(gene name synonym)|uniprotkb:Heat shock protein 70 family protein 5(gene name synonym)|uniprotkb:Heat shock protein family A member 5(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Martins et al. (2018)	imex:IM-28469|pubmed:29476059	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26439741|imex:IM-28469-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSRNOG00000016271(gene)|ensembl:ENSRNOT00000023037(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001540"(amyloid-beta binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0010008"(endosome membrane)|go:"GO:0030660"(Golgi-associated vesicle membrane)|go:"GO:0031301"(integral component of organelle membrane)|go:"GO:0042985"(negative regulation of amyloid precursor protein biosynthetic process)|interpro:IPR007084(BRICHOS)|interpro:IPR040145|mint:Q5XIE8|refseq:NP_001006964.1|rgd:620727	rgd:2843|refseq:NP_037215.1|ensembl:ENSRNOG00000018294(gene)|ensembl:ENSRNOT00000025067(transcript)|go:"GO:0001554"(luteolysis)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005788"(endoplasmic reticulum lumen)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005790"(smooth endoplasmic reticulum)|go:"GO:0005793"(endoplasmic reticulum-Golgi intermediate compartment)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006983"(ER overload response)|go:"GO:0008180"(COP9 signalosome)|go:"GO:0009314"(response to radiation)|go:"GO:0009986"(cell surface)|go:"GO:0010976"(positive regulation of neuron projection development)|go:"GO:0016020"(membrane)|go:"GO:0019899"(enzyme binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0021589"(cerebellum structural organization)|go:"GO:0021680"(cerebellar Purkinje cell layer development)|go:"GO:0030176"(integral component of endoplasmic reticulum membrane)|go:"GO:0030182"(neuron differentiation)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0030433"(ubiquitin-dependent ERAD pathway)|go:"GO:0030496"(midbody)|go:"GO:0030512"(negative regulation of transforming growth factor beta receptor signaling pathway)|go:"GO:0030968"(endoplasmic reticulum unfolded protein response)|go:"GO:0031072"(heat shock protein binding)|go:"GO:0031204"(posttranslational protein targeting to membrane, translocation)|go:"GO:0031333"(negative regulation of protein-containing complex assembly)|go:"GO:0031398"(positive regulation of protein ubiquitination)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034620"(cellular response to unfolded protein)|go:"GO:0034663"(endoplasmic reticulum chaperone complex)|go:"GO:0034976"(response to endoplasmic reticulum stress)|go:"GO:0035437"(maintenance of protein localization in endoplasmic reticulum)|go:"GO:0035690"|go:"GO:0036498"(IRE1-mediated unfolded protein response)|go:"GO:0042026"(protein refolding)|go:"GO:0042149"(cellular response to glucose starvation)|go:"GO:0042220"(response to cocaine)|go:"GO:0043022"(ribosome binding)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0044183"(protein folding chaperone)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0051085"(chaperone cofactor-dependent protein refolding)|go:"GO:0051402"(neuron apoptotic process)|go:"GO:0051603"(proteolysis involved in cellular protein catabolic process)|go:"GO:0051787"(misfolded protein binding)|go:"GO:0071236"(cellular response to antibiotic)|go:"GO:0071277"(cellular response to calcium ion)|go:"GO:0071287"(cellular response to manganese ion)|go:"GO:0071320"(cellular response to cAMP)|go:"GO:0071353"(cellular response to interleukin-4)|go:"GO:0071480"(cellular response to gamma radiation)|go:"GO:0097501"(stress response to metal ion)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|go:"GO:1901998"(toxin transport)|go:"GO:1903895"(negative regulation of IRE1-mediated unfolded protein response)|go:"GO:1904313"(response to methamphetamine hydrochloride)|go:"GO:1990090"(cellular response to nerve growth factor stimulus)|interpro:IPR013126(Heat shock protein 70)|interpro:IPR018181|interpro:IPR029047|interpro:IPR029048|interpro:IPR042050|interpro:IPR043129|mint:P06761|reactome:R-RNO-3371453|reactome:R-RNO-983170	-	-	-	figure legend:st1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10116(rat-brain-cortex)|taxid:10116(Rattus norvegicus brain cortex)	-	2020/10/30	2020/10/30	rogid:DtE+ZXAZKdCMvUW5K+jXQ5bH07M10116	rogid:5HRXkoNHYJvBA2iejRqltGRdJDw10116	rigid:3wclwrjZRvafcOruQOYnegkn54c	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q5XIE8	uniprotkb:P62909	intact:EBI-15348306|ensembl:ENSRNOP00000023037	intact:EBI-432553|uniprotkb:P17073|uniprotkb:P47933|ensembl:ENSRNOP00000023935	psi-mi:itm2b_rat(display_long)|uniprotkb:Itm2b(gene name)|psi-mi:Itm2b(display_short)|uniprotkb:Immature BRI2(gene name synonym)|uniprotkb:Transmembrane protein BRI(gene name synonym)	psi-mi:rs3_rat(display_long)|uniprotkb:Rps3(gene name)|psi-mi:Rps3(display_short)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Martins et al. (2018)	imex:IM-28469|pubmed:29476059	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26439741|imex:IM-28469-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSRNOG00000016271(gene)|ensembl:ENSRNOT00000023037(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001540"(amyloid-beta binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0010008"(endosome membrane)|go:"GO:0030660"(Golgi-associated vesicle membrane)|go:"GO:0031301"(integral component of organelle membrane)|go:"GO:0042985"(negative regulation of amyloid precursor protein biosynthetic process)|interpro:IPR007084(BRICHOS)|interpro:IPR040145|mint:Q5XIE8|refseq:NP_001006964.1|rgd:620727	rgd:619888|refseq:NP_001009239.1|ensembl:ENSRNOG00000017418(gene)|ensembl:ENSRNOT00000023935(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0003684"(damaged DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0003906"("DNA-(apurinic or apyrimidinic site) endonuclease activity")|go:"GO:0004520"(endodeoxyribonuclease activity)|go:"GO:0005634"(nucleus)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0005829"(cytosol)|go:"GO:0005840"(ribosome)|go:"GO:0005844"(polysome)|go:"GO:0005886"(plasma membrane)|go:"GO:0006281"(DNA repair)|go:"GO:0006412"(translation)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0006915"(apoptotic process)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0007059"(chromosome segregation)|go:"GO:0008017"(microtubule binding)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0012505"(endomembrane system)|go:"GO:0014069"(postsynaptic density)|go:"GO:0015631"(tubulin binding)|go:"GO:0017148"(negative regulation of translation)|go:"GO:0019899"(enzyme binding)|go:"GO:0019900"(kinase binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0022626"(cytosolic ribosome)|go:"GO:0022627"(cytosolic small ribosomal subunit)|go:"GO:0030425"(dendrite)|go:"GO:0030544"(Hsp70 protein binding)|go:"GO:0031116"(positive regulation of microtubule polymerization)|go:"GO:0031334"(positive regulation of protein-containing complex assembly)|go:"GO:0031397"(negative regulation of protein ubiquitination)|go:"GO:0032079"(positive regulation of endodeoxyribonuclease activity)|go:"GO:0032357"(oxidized purine DNA binding)|go:"GO:0032358"(oxidized pyrimidine DNA binding)|go:"GO:0032587"(ruffle membrane)|go:"GO:0032743"(positive regulation of interleukin-2 production)|go:"GO:0034614"(cellular response to reactive oxygen species)|go:"GO:0042104"(positive regulation of activated T cell proliferation)|go:"GO:0042769"(obsolete DNA damage response, detection of DNA damage)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0043507"(positive regulation of JUN kinase activity)|go:"GO:0044390"(ubiquitin-like protein conjugating enzyme binding)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045202"(synapse)|go:"GO:0045738"(negative regulation of DNA repair)|go:"GO:0045739"(positive regulation of DNA repair)|go:"GO:0050862"(positive regulation of T cell receptor signaling pathway)|go:"GO:0051018"(protein kinase A binding)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|go:"GO:0051225"(spindle assembly)|go:"GO:0051301"(cell division)|go:"GO:0051879"(Hsp90 protein binding)|go:"GO:0061481"(response to TNF agonist)|go:"GO:0070181"(small ribosomal subunit rRNA binding)|go:"GO:0070301"(cellular response to hydrogen peroxide)|go:"GO:0071159"(NF-kappaB complex)|go:"GO:0071356"(cellular response to tumor necrosis factor)|go:"GO:0072686"(mitotic spindle)|go:"GO:0097100"(supercoiled DNA binding)|go:"GO:0140078"("class I DNA-(apurinic or apyrimidinic site) endonuclease activity")|go:"GO:1901224"(positive regulation of NIK/NF-kappaB signaling)|go:"GO:1902231"(positive regulation of intrinsic apoptotic signaling pathway in response to DNA damage)|go:"GO:1902546"(positive regulation of DNA N-glycosylase activity)|go:"GO:2001235"(positive regulation of apoptotic signaling pathway)|go:"GO:2001272"(positive regulation of cysteine-type endopeptidase activity involved in execution phase of apoptosis)|interpro:IPR001351(Ribosomal protein S3, C-terminal)|interpro:IPR004044(K Homology, type 2)|interpro:IPR005703(Ribosomal protein S3, eukaryotic/archaeal)|interpro:IPR009019(K Homology, prokaryotic type)|interpro:IPR015946(K homology-like, alpha/beta)|go:"GO:1905053"(positive regulation of base-excision repair)|go:"GO:1990090"(cellular response to nerve growth factor stimulus)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR018280|interpro:IPR036419|mint:P62909|reactome:R-RNO-156827|reactome:R-RNO-1799339|reactome:R-RNO-6791226|reactome:R-RNO-72649|reactome:R-RNO-72689|reactome:R-RNO-72695|reactome:R-RNO-72702|reactome:R-RNO-72706|reactome:R-RNO-975956|reactome:R-RNO-975957	-	-	-	figure legend:st1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10116(rat-brain-cortex)|taxid:10116(Rattus norvegicus brain cortex)	-	2020/10/30	2020/10/30	rogid:DtE+ZXAZKdCMvUW5K+jXQ5bH07M10116	rogid:f4Vh6HESE+lKZinjkJ883IG3wiY10116	rigid:3wclwrjZRvafcOruQOYnegkn54c	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q5XIE8	uniprotkb:P86252	intact:EBI-15348306|ensembl:ENSRNOP00000023037	intact:EBI-1638520	psi-mi:itm2b_rat(display_long)|uniprotkb:Itm2b(gene name)|psi-mi:Itm2b(display_short)|uniprotkb:Immature BRI2(gene name synonym)|uniprotkb:Transmembrane protein BRI(gene name synonym)	psi-mi:pura_rat(display_long)|uniprotkb:Pura(gene name)|psi-mi:Pura(display_short)|uniprotkb:Purine-rich single-stranded DNA-binding protein alpha(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Martins et al. (2018)	imex:IM-28469|pubmed:29476059	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26439741|imex:IM-28469-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSRNOG00000016271(gene)|ensembl:ENSRNOT00000023037(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001540"(amyloid-beta binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0010008"(endosome membrane)|go:"GO:0030660"(Golgi-associated vesicle membrane)|go:"GO:0031301"(integral component of organelle membrane)|go:"GO:0042985"(negative regulation of amyloid precursor protein biosynthetic process)|interpro:IPR007084(BRICHOS)|interpro:IPR040145|mint:Q5XIE8|refseq:NP_001006964.1|rgd:620727	interpro:IPR006628(PUR-alpha/beta/gamma, DNA/RNA-binding)|rgd:1308543|mint:P86252|interpro:IPR030500|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000900"(translation repressor activity, mRNA regulatory element binding)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0003677"(DNA binding)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0003691"(double-stranded telomeric DNA binding)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006268"(DNA unwinding involved in DNA replication)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007399"(nervous system development)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0014069"(postsynaptic density)|go:"GO:0030154"(cell differentiation)|go:"GO:0030425"(dendrite)|go:"GO:0032422"(purine-rich negative regulatory element binding)|go:"GO:0032839"(dendrite cytoplasm)|go:"GO:0043025"(neuronal cell body)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0046332"(SMAD binding)|go:"GO:0046651"(lymphocyte proliferation)|go:"GO:0050673"(epithelial cell proliferation)|go:"GO:0098794"(postsynapse)|go:"GO:0098963"(dendritic transport of messenger ribonucleoprotein complex)|go:"GO:0098978"(glutamatergic synapse)	-	-	-	figure legend:st1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10116(rat-brain-cortex)|taxid:10116(Rattus norvegicus brain cortex)	-	2020/10/30	2020/10/30	rogid:DtE+ZXAZKdCMvUW5K+jXQ5bH07M10116	rogid:S+5CDoCwS0nqAB0KlkB+AzxN7Ks10116	rigid:3wclwrjZRvafcOruQOYnegkn54c	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q5XIE8	uniprotkb:P16036	intact:EBI-15348306|ensembl:ENSRNOP00000023037	intact:EBI-916656	psi-mi:itm2b_rat(display_long)|uniprotkb:Itm2b(gene name)|psi-mi:Itm2b(display_short)|uniprotkb:Immature BRI2(gene name synonym)|uniprotkb:Transmembrane protein BRI(gene name synonym)	psi-mi:mpcp_rat(display_long)|uniprotkb:Phosphate transport protein(gene name synonym)|uniprotkb:Solute carrier family 25 member 3(gene name synonym)|uniprotkb:Slc25a3(gene name)|psi-mi:Slc25a3(display_short)|uniprotkb:Phc(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Martins et al. (2018)	imex:IM-28469|pubmed:29476059	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26439741|imex:IM-28469-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSRNOG00000016271(gene)|ensembl:ENSRNOT00000023037(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001540"(amyloid-beta binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0010008"(endosome membrane)|go:"GO:0030660"(Golgi-associated vesicle membrane)|go:"GO:0031301"(integral component of organelle membrane)|go:"GO:0042985"(negative regulation of amyloid precursor protein biosynthetic process)|interpro:IPR007084(BRICHOS)|interpro:IPR040145|mint:Q5XIE8|refseq:NP_001006964.1|rgd:620727	rgd:70986|interpro:IPR018108|interpro:IPR023395|mint:P16036|interpro:IPR044677|go:"GO:0005315"(inorganic phosphate transmembrane transporter activity)|go:"GO:0005739"(mitochondrion)|go:"GO:0015317"("phosphate:proton symporter activity")|go:"GO:0031305"(integral component of mitochondrial inner membrane)|go:"GO:0035435"(phosphate ion transmembrane transport)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:1990547"(mitochondrial phosphate ion transmembrane transport)	-	-	-	figure legend:st1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10116(rat-brain-cortex)|taxid:10116(Rattus norvegicus brain cortex)	-	2020/10/30	2020/10/30	rogid:DtE+ZXAZKdCMvUW5K+jXQ5bH07M10116	rogid:BwRf4GKI4G+aBu3r29CqmCdOHyM10116	rigid:3wclwrjZRvafcOruQOYnegkn54c	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q5XIE8	uniprotkb:P61980	intact:EBI-15348306|ensembl:ENSRNOP00000023037	intact:EBI-299761|ensembl:ENSRNOP00000025915|uniprotkb:Q07244|uniprotkb:Q15671|uniprotkb:Q60577|uniprotkb:Q922Y7|uniprotkb:Q96J62	psi-mi:itm2b_rat(display_long)|uniprotkb:Itm2b(gene name)|psi-mi:Itm2b(display_short)|uniprotkb:Immature BRI2(gene name synonym)|uniprotkb:Transmembrane protein BRI(gene name synonym)	psi-mi:hnrpk_rat(display_long)|uniprotkb:Hnrnpk(gene name)|psi-mi:Hnrnpk(display_short)|uniprotkb:Hnrpk(gene name synonym)|uniprotkb:dC stretch-binding protein(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Martins et al. (2018)	imex:IM-28469|pubmed:29476059	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26439741|imex:IM-28469-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSRNOG00000016271(gene)|ensembl:ENSRNOT00000023037(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001540"(amyloid-beta binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0010008"(endosome membrane)|go:"GO:0030660"(Golgi-associated vesicle membrane)|go:"GO:0031301"(integral component of organelle membrane)|go:"GO:0042985"(negative regulation of amyloid precursor protein biosynthetic process)|interpro:IPR007084(BRICHOS)|interpro:IPR040145|mint:Q5XIE8|refseq:NP_001006964.1|rgd:620727	ensembl:ENSRNOG00000019113(gene)|ensembl:ENSRNOT00000025916(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000987"(cis-regulatory region sequence-specific DNA binding)|go:"GO:0001541"(ovarian follicle development)|go:"GO:0001822"(kidney development)|go:"GO:0001889"(liver development)|go:"GO:0002102"(podosome)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0003730"(mRNA 3'-UTR binding)|go:"GO:0005521"(lamin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0005938"(cell cortex)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006397"(mRNA processing)|go:"GO:0006953"(acute-phase response)|go:"GO:0007417"(central nervous system development)|go:"GO:0007422"(peripheral nervous system development)|go:"GO:0007568"(aging)|go:"GO:0008380"(RNA splicing)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0010494"(cytoplasmic stress granule)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0010976"(positive regulation of neuron projection development)|go:"GO:0010988"(regulation of low-density lipoprotein particle clearance)|go:"GO:0014069"(postsynaptic density)|go:"GO:0014823"(response to activity)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0021549"(cerebellum development)|go:"GO:0021766"(hippocampus development)|go:"GO:0021987"(cerebral cortex development)|go:"GO:0030324"(lung development)|go:"GO:0030628"(pre-mRNA 3'-splice site binding)|go:"GO:0031072"(heat shock protein binding)|go:"GO:0000785"(chromatin)|go:"GO:0032869"(cellular response to insulin stimulus)|go:"GO:0032993"(protein-DNA complex)|go:"GO:0033120"(positive regulation of RNA splicing)|go:"GO:0042802"(identical protein binding)|go:"GO:0042805"(actinin binding)|go:"GO:0043010"(camera-type eye development)|go:"GO:0043021"(ribonucleoprotein complex binding)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043197"(dendritic spine)|go:"GO:0043679"(axon terminus)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048024"(regulation of mRNA splicing, via spliceosome)|go:"GO:0048025"(negative regulation of mRNA splicing, via spliceosome)|go:"GO:0048260"(positive regulation of receptor-mediated endocytosis)|go:"GO:0048538"(thymus development)|go:"GO:0050804"(modulation of chemical synaptic transmission)|go:"GO:0050806"(positive regulation of synaptic transmission)|go:"GO:0051117"(ATPase binding)|go:"GO:0060999"(positive regulation of dendritic spine development)|go:"GO:0071013"(catalytic step 2 spliceosome)|go:"GO:0071230"(cellular response to amino acid stimulus)|go:"GO:0071333"(cellular response to glucose stimulus)|go:"GO:0032091"(negative regulation of protein binding)|go:"GO:0090129"(positive regulation of synapse maturation)|go:"GO:0098794"(postsynapse)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099175"(regulation of postsynapse organization)|go:"GO:1900273"(positive regulation of long-term synaptic potentiation)|go:"GO:1902074"(response to salt)|go:"GO:1902165"(regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator)|go:"GO:1903861"(positive regulation of dendrite extension)|go:"GO:1904322"(cellular response to forskolin)|go:"GO:1905599"(positive regulation of low-density lipoprotein receptor activity)|go:"GO:1990715"(mRNA CDS binding)|go:"GO:1990829"(C-rich single-stranded DNA binding)|go:"GO:2000010"(positive regulation of protein localization to cell surface)|go:"GO:2000173"(negative regulation of branching morphogenesis of a nerve)|interpro:IPR004087(K Homology)|interpro:IPR004088(K Homology, type 1)|interpro:IPR012987(ROK, N-terminal)|interpro:IPR033090|interpro:IPR036612|mint:P61980|reactome:R-RNO-4570464|reactome:R-RNO-72163|go:"GO:0072752"(cellular response to rapamycin)|rgd:71058|refseq:NP_476482.1|refseq:XP_006253616.1	-	-	-	figure legend:st1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10116(rat-brain-cortex)|taxid:10116(Rattus norvegicus brain cortex)	-	2020/10/30	2020/10/30	rogid:DtE+ZXAZKdCMvUW5K+jXQ5bH07M10116	rogid:YZQD5JJkHPUMtZ4XUA9fQkNfXzc10116	rigid:3wclwrjZRvafcOruQOYnegkn54c	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q5XIE8	uniprotkb:P03994	intact:EBI-15348306|ensembl:ENSRNOP00000023037	intact:EBI-5747169|ensembl:ENSRNOP00000040553|ensembl:ENSRNOP00000045959	psi-mi:itm2b_rat(display_long)|uniprotkb:Itm2b(gene name)|psi-mi:Itm2b(display_short)|uniprotkb:Immature BRI2(gene name synonym)|uniprotkb:Transmembrane protein BRI(gene name synonym)	psi-mi:hpln1_rat(display_long)|uniprotkb:Hapln1(gene name)|psi-mi:Hapln1(display_short)|uniprotkb:Crtl1(gene name synonym)|uniprotkb:Cartilage-linking protein 1(gene name synonym)|uniprotkb:Proteoglycan link protein(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Martins et al. (2018)	imex:IM-28469|pubmed:29476059	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26439741|imex:IM-28469-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSRNOG00000016271(gene)|ensembl:ENSRNOT00000023037(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001540"(amyloid-beta binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0010008"(endosome membrane)|go:"GO:0030660"(Golgi-associated vesicle membrane)|go:"GO:0031301"(integral component of organelle membrane)|go:"GO:0042985"(negative regulation of amyloid precursor protein biosynthetic process)|interpro:IPR007084(BRICHOS)|interpro:IPR040145|mint:Q5XIE8|refseq:NP_001006964.1|rgd:620727	rgd:2412|refseq:XP_006231810.1|ensembl:ENSRNOG00000032002(gene)|ensembl:ENSRNOT00000042958(transcript)|ensembl:ENSRNOT00000043196(transcript)|go:"GO:0001501"(skeletal system development)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005540"(hyaluronic acid binding)|go:"GO:0005576"(extracellular region)|go:"GO:0007155"(cell adhesion)|go:"GO:0007417"(central nervous system development)|go:"GO:0031012"(extracellular matrix)|go:"GO:0045202"(synapse)|interpro:IPR000538(Link)|interpro:IPR003599(Immunoglobulin subtype)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR013106(Immunoglobulin V-set)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR016186(C-type lectin-like)|interpro:IPR016187(C-type lectin fold)|interpro:IPR036179|mint:P03994|reactome:R-RNO-3000178	-	-	-	figure legend:st1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10116(rat-brain-cortex)|taxid:10116(Rattus norvegicus brain cortex)	-	2020/10/30	2020/10/30	rogid:DtE+ZXAZKdCMvUW5K+jXQ5bH07M10116	rogid:TQ7UE3ZsSgesM1DKbMig4A1kCYQ10116	rigid:3wclwrjZRvafcOruQOYnegkn54c	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q5XIE8	uniprotkb:Q6AY09	intact:EBI-15348306|ensembl:ENSRNOP00000023037	intact:EBI-1638443|ensembl:ENSRNOP00000015518	psi-mi:itm2b_rat(display_long)|uniprotkb:Itm2b(gene name)|psi-mi:Itm2b(display_short)|uniprotkb:Immature BRI2(gene name synonym)|uniprotkb:Transmembrane protein BRI(gene name synonym)	psi-mi:hnrh2_rat(display_long)|uniprotkb:Hnrnph2(gene name)|psi-mi:Hnrnph2(display_short)|uniprotkb:Hnrph2(gene name synonym)|uniprotkb:Heterogeneous nuclear ribonucleoprotein H'(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Martins et al. (2018)	imex:IM-28469|pubmed:29476059	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26439741|imex:IM-28469-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSRNOG00000016271(gene)|ensembl:ENSRNOT00000023037(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001540"(amyloid-beta binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0010008"(endosome membrane)|go:"GO:0030660"(Golgi-associated vesicle membrane)|go:"GO:0031301"(integral component of organelle membrane)|go:"GO:0042985"(negative regulation of amyloid precursor protein biosynthetic process)|interpro:IPR007084(BRICHOS)|interpro:IPR040145|mint:Q5XIE8|refseq:NP_001006964.1|rgd:620727	rgd:1549784|refseq:NP_001014041.1|refseq:XP_006257281.1|refseq:XP_006257282.1|refseq:XP_006257283.1|ensembl:ENSRNOG00000011661(gene)|ensembl:ENSRNOT00000015518(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0005829"(cytosol)|go:"GO:0014069"(postsynaptic density)|go:"GO:0043484"(regulation of RNA splicing)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR012996(Zinc finger, CHHC-type)|interpro:IPR035979|mint:Q6AY09|reactome:R-RNO-72163|go:"GO:0005654"(nucleoplasm)	-	-	-	figure legend:st1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10116(rat-brain-cortex)|taxid:10116(Rattus norvegicus brain cortex)	-	2020/10/30	2020/10/30	rogid:DtE+ZXAZKdCMvUW5K+jXQ5bH07M10116	rogid:iYxEIXbVEciSTaqi1m4uhyPppRE10116	rigid:3wclwrjZRvafcOruQOYnegkn54c	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q5XIE8	uniprotkb:P01026	intact:EBI-15348306|ensembl:ENSRNOP00000023037	intact:EBI-6096102|uniprotkb:Q9ET19|uniprotkb:Q9QV57|uniprotkb:Q9QV58	psi-mi:itm2b_rat(display_long)|uniprotkb:Itm2b(gene name)|psi-mi:Itm2b(display_short)|uniprotkb:Immature BRI2(gene name synonym)|uniprotkb:Transmembrane protein BRI(gene name synonym)	psi-mi:co3_rat(display_long)|uniprotkb:C3(gene name)|psi-mi:C3(display_short)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Martins et al. (2018)	imex:IM-28469|pubmed:29476059	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26439741|imex:IM-28469-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSRNOG00000016271(gene)|ensembl:ENSRNOT00000023037(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001540"(amyloid-beta binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0010008"(endosome membrane)|go:"GO:0030660"(Golgi-associated vesicle membrane)|go:"GO:0031301"(integral component of organelle membrane)|go:"GO:0042985"(negative regulation of amyloid precursor protein biosynthetic process)|interpro:IPR007084(BRICHOS)|interpro:IPR040145|mint:Q5XIE8|refseq:NP_001006964.1|rgd:620727	mint:P01026|interpro:IPR035711|interpro:IPR035815|interpro:IPR036595|interpro:IPR013783(Immunoglobulin-like fold)|rgd:2232|refseq:NP_058690.2|interpro:IPR009048(Alpha-macroglobulin, receptor-binding)|interpro:IPR011626(A-macroglobulin complement component)|interpro:IPR002890(Alpha-2-macroglobulin, N-terminal)|interpro:IPR011625(Alpha-2-macroglobulin, N-terminal 2)|interpro:IPR000020(Anaphylatoxin/fibulin)|interpro:IPR018081|interpro:IPR001840(Complement C3a/C4a/C5a anaphylatoxin)|interpro:IPR001599(Alpha-2-macroglobulin)|interpro:IPR019742|interpro:IPR001134(Netrin, C-terminal)|interpro:IPR018933|interpro:IPR008930(Terpenoid cylases/protein prenyltransferase alpha-alpha toroid)|interpro:IPR008993(TIMP-like, OB-fold)|interpro:IPR040839|interpro:IPR041425|interpro:IPR041555|go:"GO:0001798"(positive regulation of type IIa hypersensitivity)|go:"GO:0001934"(positive regulation of protein phosphorylation)|go:"GO:0001970"(positive regulation of activation of membrane attack complex)|go:"GO:0002507"(tolerance induction)|go:"GO:0004866"(endopeptidase inhibitor activity)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0006631"(fatty acid metabolic process)|go:"GO:0006935"(chemotaxis)|go:"GO:0006954"(inflammatory response)|go:"GO:0006956"(complement activation)|go:"GO:0006957"(complement activation, alternative pathway)|go:"GO:0006958"(complement activation, classical pathway)|go:"GO:0007596"(blood coagulation)|go:"GO:0008289"(lipid binding)|go:"GO:0009617"(response to bacterium)|go:"GO:0009986"(cell surface)|go:"GO:0010575"(positive regulation of vascular endothelial growth factor production)|go:"GO:0010828"(positive regulation of glucose transmembrane transport)|go:"GO:0010866"(regulation of triglyceride biosynthetic process)|go:"GO:0010884"(positive regulation of lipid storage)|go:"GO:0016322"(neuron remodeling)|go:"GO:0031715"(C5L2 anaphylatoxin chemotactic receptor binding)|go:"GO:0032026"(response to magnesium ion)|go:"GO:0032355"(response to estradiol)|go:"GO:0032570"(response to progesterone)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035846"(oviduct epithelium development)|go:"GO:0035886"(vascular associated smooth muscle cell differentiation)|go:"GO:0043627"(response to estrogen)|go:"GO:0045745"(positive regulation of G protein-coupled receptor signaling pathway)|go:"GO:0045766"(positive regulation of angiogenesis)|go:"GO:0048260"(positive regulation of receptor-mediated endocytosis)|go:"GO:0048639"(positive regulation of developmental growth)|go:"GO:0050766"(positive regulation of phagocytosis)|go:"GO:0051384"(response to glucocorticoid)|go:"GO:0060041"(retina development in camera-type eye)|go:"GO:0060100"(positive regulation of phagocytosis, engulfment)|go:"GO:0070374"(positive regulation of ERK1 and ERK2 cascade)|go:"GO:0097242"(amyloid-beta clearance)|go:"GO:0097278"(complement-dependent cytotoxicity)|go:"GO:0150062"(complement-mediated synapse pruning)|go:"GO:0150064"(vertebrate eye-specific patterning)|go:"GO:1901555"(response to paclitaxel)|go:"GO:1905114"(cell surface receptor signaling pathway involved in cell-cell signaling)|go:"GO:2000427"(positive regulation of apoptotic cell clearance)|rcsb pdb:1QQF|rcsb pdb:1QSJ|reactome:R-RNO-173736|reactome:R-RNO-174577|reactome:R-RNO-198933|reactome:R-RNO-375276|reactome:R-RNO-381426|reactome:R-RNO-418594|reactome:R-RNO-6798695|reactome:R-RNO-8957275|reactome:R-RNO-977606	-	-	-	figure legend:st1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10116(rat-brain-cortex)|taxid:10116(Rattus norvegicus brain cortex)	-	2020/10/30	2020/10/30	rogid:DtE+ZXAZKdCMvUW5K+jXQ5bH07M10116	rogid:7yW59Wpi5Yq8jY85OvBPgOqOMAc10116	rigid:3wclwrjZRvafcOruQOYnegkn54c	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q5XIE8	uniprotkb:Q3KRE8	intact:EBI-15348306|ensembl:ENSRNOP00000023037	intact:EBI-349199|ensembl:ENSRNOP00000023582|ensembl:ENSRNOP00000073323|uniprotkb:A3KMR7|uniprotkb:P04691	psi-mi:itm2b_rat(display_long)|uniprotkb:Itm2b(gene name)|psi-mi:Itm2b(display_short)|uniprotkb:Immature BRI2(gene name synonym)|uniprotkb:Transmembrane protein BRI(gene name synonym)	psi-mi:tbb2b_rat(display_long)|uniprotkb:T beta-15(gene name synonym)|uniprotkb:Tubb2b(gene name)|psi-mi:Tubb2b(display_short)|uniprotkb:Tubb2a(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Martins et al. (2018)	imex:IM-28469|pubmed:29476059	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26439741|imex:IM-28469-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSRNOG00000016271(gene)|ensembl:ENSRNOT00000023037(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001540"(amyloid-beta binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0010008"(endosome membrane)|go:"GO:0030660"(Golgi-associated vesicle membrane)|go:"GO:0031301"(integral component of organelle membrane)|go:"GO:0042985"(negative regulation of amyloid precursor protein biosynthetic process)|interpro:IPR007084(BRICHOS)|interpro:IPR040145|mint:Q5XIE8|refseq:NP_001006964.1|rgd:620727	rgd:1309427|refseq:NP_001013908.2|ensembl:ENSRNOG00000017445(gene)|ensembl:ENSRNOT00000023582(transcript)|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0001764"(neuron migration)|go:"GO:0005200"(structural constituent of cytoskeleton)|go:"GO:0005525"(GTP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005874"(microtubule)|go:"GO:0007017"(microtubule-based process)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0050804"(modulation of chemical synaptic transmission)|go:"GO:0098685"(Schaffer collateral - CA1 synapse)|go:"GO:1902669"(positive regulation of axon guidance)|go:"GO:1990403"(embryonic brain development)|interpro:IPR000217(Tubulin)|interpro:IPR002453(Beta tubulin)|interpro:IPR003008(Tubulin/FtsZ, GTPase)|interpro:IPR008280(Tubulin/FtsZ, C-terminal)|interpro:IPR013838(Beta tubulin, autoregulation binding site)|ensembl:ENSRNOT00000083705(transcript)|reactome:R-RNO-5626467|interpro:IPR017975|interpro:IPR018316|reactome:R-RNO-5663220|reactome:R-RNO-6807878|reactome:R-RNO-6811434|interpro:IPR023123|reactome:R-RNO-6811436|reactome:R-RNO-68877|reactome:R-RNO-8852276|reactome:R-RNO-8955332|interpro:IPR036525|interpro:IPR037103|mint:Q3KRE8|reactome:R-RNO-190840|reactome:R-RNO-9646399|reactome:R-RNO-9648025|reactome:R-RNO-9668328|reactome:R-RNO-2132295|reactome:R-RNO-2467813|reactome:R-RNO-2500257|reactome:R-RNO-3371497|reactome:R-RNO-380320|reactome:R-RNO-437239|reactome:R-RNO-5610787|reactome:R-RNO-5617833|reactome:R-RNO-5620924|reactome:R-RNO-983189	-	-	-	figure legend:st1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10116(rat-brain-cortex)|taxid:10116(Rattus norvegicus brain cortex)	-	2020/10/30	2020/10/30	rogid:DtE+ZXAZKdCMvUW5K+jXQ5bH07M10116	rogid:sluQMryNuOvp6xlV558+agiRwvE10116	rigid:3wclwrjZRvafcOruQOYnegkn54c	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q5XIE8	uniprotkb:Q6P7B0	intact:EBI-15348306|ensembl:ENSRNOP00000023037	intact:EBI-16221697|ensembl:ENSRNOP00000006128	psi-mi:itm2b_rat(display_long)|uniprotkb:Itm2b(gene name)|psi-mi:Itm2b(display_short)|uniprotkb:Immature BRI2(gene name synonym)|uniprotkb:Transmembrane protein BRI(gene name synonym)	psi-mi:sywc_rat(display_long)|uniprotkb:Wars1(gene name)|psi-mi:Wars1(display_short)|uniprotkb:Tryptophanyl-tRNA synthetase(gene name synonym)|uniprotkb:Wars(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Martins et al. (2018)	imex:IM-28469|pubmed:29476059	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26439741|imex:IM-28469-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSRNOG00000016271(gene)|ensembl:ENSRNOT00000023037(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001540"(amyloid-beta binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0010008"(endosome membrane)|go:"GO:0030660"(Golgi-associated vesicle membrane)|go:"GO:0031301"(integral component of organelle membrane)|go:"GO:0042985"(negative regulation of amyloid precursor protein biosynthetic process)|interpro:IPR007084(BRICHOS)|interpro:IPR040145|mint:Q5XIE8|refseq:NP_001006964.1|rgd:620727	ensembl:ENSRNOG00000004359(gene)|ensembl:ENSRNOT00000006128(transcript)|go:"GO:0001525"(angiogenesis)|go:"GO:0001933"(negative regulation of protein phosphorylation)|go:"GO:0004830"(tryptophan-tRNA ligase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006436"(tryptophanyl-tRNA aminoacylation)|go:"GO:0006469"(negative regulation of protein kinase activity)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010835"(regulation of protein ADP-ribosylation)|go:"GO:0019210"(kinase inhibitor activity)|go:"GO:0019901"(protein kinase binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0031334"(positive regulation of protein-containing complex assembly)|go:"GO:0032991"(protein-containing complex)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0045765"(regulation of angiogenesis)|interpro:IPR000738(WHEP-TRS)|interpro:IPR001412(Aminoacyl-tRNA synthetase, class I, conserved site)|interpro:IPR002305(Aminoacyl-tRNA synthetase, class Ib)|interpro:IPR002306(Tryptophanyl-tRNA synthetase, class Ib)|interpro:IPR009068(S15/NS1, RNA-binding)|interpro:IPR014729(Rossmann-like alpha/beta/alpha sandwich fold)|mint:Q6P7B0|refseq:XP_006240604.1|refseq:XP_008763034.1|rgd:1308278	-	-	-	figure legend:st1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10116(rat-brain-cortex)|taxid:10116(Rattus norvegicus brain cortex)	-	2020/10/30	2020/10/30	rogid:DtE+ZXAZKdCMvUW5K+jXQ5bH07M10116	rogid:wDEyHrQQZA/Jbz9CWIIcusLZXxE10116	rigid:3wclwrjZRvafcOruQOYnegkn54c	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q5XIE8	uniprotkb:P61765	intact:EBI-15348306|ensembl:ENSRNOP00000023037	intact:EBI-1029097|uniprotkb:Q28208|uniprotkb:Q62759|uniprotkb:Q64320|uniprotkb:Q96TG8|ensembl:ENSRNOP00000021178	psi-mi:itm2b_rat(display_long)|uniprotkb:Itm2b(gene name)|psi-mi:Itm2b(display_short)|uniprotkb:Immature BRI2(gene name synonym)|uniprotkb:Transmembrane protein BRI(gene name synonym)	psi-mi:stxb1_rat(display_long)|uniprotkb:Stxbp1(gene name)|psi-mi:Stxbp1(display_short)|uniprotkb:Unc18a(gene name synonym)|uniprotkb:Protein unc-18 homolog 1(gene name synonym)|uniprotkb:Protein unc-18 homolog A(gene name synonym)|uniprotkb:N-Sec1(gene name synonym)|uniprotkb:rbSec1(gene name synonym)|uniprotkb:p67(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Martins et al. (2018)	imex:IM-28469|pubmed:29476059	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26439741|imex:IM-28469-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSRNOG00000016271(gene)|ensembl:ENSRNOT00000023037(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001540"(amyloid-beta binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0010008"(endosome membrane)|go:"GO:0030660"(Golgi-associated vesicle membrane)|go:"GO:0031301"(integral component of organelle membrane)|go:"GO:0042985"(negative regulation of amyloid precursor protein biosynthetic process)|interpro:IPR007084(BRICHOS)|interpro:IPR040145|mint:Q5XIE8|refseq:NP_001006964.1|rgd:620727	rgd:3785|refseq:NP_037170.1|ensembl:ENSRNOG00000015420(gene)|ensembl:ENSRNOT00000021178(transcript)|go:"GO:0000149"(SNARE binding)|go:"GO:0002576"(platelet degranulation)|go:"GO:0003006"(developmental process involved in reproduction)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005886"(plasma membrane)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006887"(exocytosis)|go:"GO:0006904"(vesicle docking involved in exocytosis)|go:"GO:0007269"(neurotransmitter secretion)|go:"GO:0007274"(neuromuscular synaptic transmission)|go:"GO:0007412"(axon target recognition)|go:"GO:0010807"(regulation of synaptic vesicle priming)|go:"GO:0016082"(synaptic vesicle priming)|go:"GO:0016188"(synaptic vesicle maturation)|go:"GO:0016192"(vesicle-mediated transport)|go:"GO:0017075"(syntaxin-1 binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0019905"(syntaxin binding)|go:"GO:0030141"(secretory granule)|go:"GO:0030424"(axon)|go:"GO:0031091"(platelet alpha granule)|go:"GO:0031333"(negative regulation of protein-containing complex assembly)|go:"GO:0031338"(regulation of vesicle fusion)|go:"GO:0032355"(response to estradiol)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035493"(SNARE complex assembly)|go:"GO:0035544"(negative regulation of SNARE complex assembly)|go:"GO:0042802"(identical protein binding)|go:"GO:0043195"(terminal bouton)|go:"GO:0043274"(phospholipase binding)|go:"GO:0043306"(positive regulation of mast cell degranulation)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0045335"(phagocytic vesicle)|go:"GO:0045921"(positive regulation of exocytosis)|go:"GO:0045956"(positive regulation of calcium ion-dependent exocytosis)|go:"GO:0047485"(protein N-terminus binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0048787"(presynaptic active zone membrane)|go:"GO:0050821"(protein stabilization)|go:"GO:0060292"(long-term synaptic depression)|go:"GO:0070527"(platelet aggregation)|go:"GO:0071346"(cellular response to interferon-gamma)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0098793"(presynapse)|go:"GO:0098794"(postsynapse)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099525"(presynaptic dense core vesicle exocytosis)|go:"GO:0106022"(positive regulation of vesicle docking)|go:"GO:1903296"(positive regulation of glutamate secretion, neurotransmission)|go:"GO:2000367"(regulation of acrosomal vesicle exocytosis)|interpro:IPR001619(Sec1-like protein)|interpro:IPR027482|interpro:IPR036045|interpro:IPR043127|interpro:IPR043154|mint:P61765|rcsb pdb:3C98|rcsb pdb:3PUJ|rcsb pdb:4JEH|rcsb pdb:4JEU|rcsb pdb:6LPC|reactome:R-RNO-181429|reactome:R-RNO-181430|reactome:R-RNO-210500|reactome:R-RNO-212676|reactome:R-RNO-264642|reactome:R-RNO-888590|go:"GO:0032229"(negative regulation of synaptic transmission, GABAergic)|refseq:XP_006234001.1|dip:DIP-766N	-	-	-	figure legend:st1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10116(rat-brain-cortex)|taxid:10116(Rattus norvegicus brain cortex)	-	2020/10/30	2020/10/30	rogid:DtE+ZXAZKdCMvUW5K+jXQ5bH07M10116	rogid:yUYi89hDkfMdQ1BdH52swZQFCLk10116	rigid:3wclwrjZRvafcOruQOYnegkn54c	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q5XIE8	uniprotkb:P07825	intact:EBI-15348306|ensembl:ENSRNOP00000023037	intact:EBI-976085|uniprotkb:Q499R3	psi-mi:itm2b_rat(display_long)|uniprotkb:Itm2b(gene name)|psi-mi:Itm2b(display_short)|uniprotkb:Immature BRI2(gene name synonym)|uniprotkb:Transmembrane protein BRI(gene name synonym)	psi-mi:syph_rat(display_long)|uniprotkb:Major synaptic vesicle protein p38(gene name synonym)|uniprotkb:Syp(gene name)|psi-mi:Syp(display_short)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Martins et al. (2018)	imex:IM-28469|pubmed:29476059	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26439741|imex:IM-28469-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSRNOG00000016271(gene)|ensembl:ENSRNOT00000023037(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001540"(amyloid-beta binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0010008"(endosome membrane)|go:"GO:0030660"(Golgi-associated vesicle membrane)|go:"GO:0031301"(integral component of organelle membrane)|go:"GO:0042985"(negative regulation of amyloid precursor protein biosynthetic process)|interpro:IPR007084(BRICHOS)|interpro:IPR040145|mint:Q5XIE8|refseq:NP_001006964.1|rgd:620727	go:"GO:0030285"(integral component of synaptic vesicle membrane)|go:"GO:0048169"(regulation of long-term neuronal synaptic plasticity)|go:"GO:0030672"(synaptic vesicle membrane)|go:"GO:0048172"(regulation of short-term neuronal synaptic plasticity)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0031594"(neuromuscular junction)|go:"GO:0048488"(synaptic vesicle endocytosis)|go:"GO:0048786"(presynaptic active zone)|go:"GO:0060076"(excitatory synapse)|go:"GO:0032991"(protein-containing complex)|go:"GO:0071310"(cellular response to organic substance)|go:"GO:0042169"(SH2 domain binding)|go:"GO:0098685"(Schaffer collateral - CA1 synapse)|go:"GO:0042734"(presynaptic membrane)|go:"GO:1904645"(response to amyloid-beta)|go:"GO:2000300"(regulation of synaptic vesicle exocytosis)|go:"GO:0042802"(identical protein binding)|go:"GO:0043005"(neuron projection)|go:"GO:0043195"(terminal bouton)|go:"GO:2000474"(regulation of opioid receptor signaling pathway)|go:"GO:0043229"(intracellular organelle)|go:"GO:0044306"(neuron projection terminus)|go:"GO:0044309"(neuron spine)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045202"(synapse)|go:"GO:0048168"(regulation of neuronal synaptic plasticity)|go:"GO:0000149"(SNARE binding)|go:"GO:0006897"(endocytosis)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0014069"(postsynaptic density)|go:"GO:0015485"(cholesterol binding)|go:"GO:0016020"(membrane)|go:"GO:0017075"(syntaxin-1 binding)|go:"GO:0019904"(protein domain specific binding)|rgd:3802|refseq:NP_036796.1|interpro:IPR008253(Marvel)|interpro:IPR001285(Synaptophysin/synaptoporin)|interpro:IPR028714|mint:P07825	-	-	-	figure legend:st1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10116(rat-brain-cortex)|taxid:10116(Rattus norvegicus brain cortex)	-	2020/10/30	2020/10/30	rogid:DtE+ZXAZKdCMvUW5K+jXQ5bH07M10116	rogid:nG9lA5IrA7dLVQ2QlJ7VhtruLLg10116	rigid:3wclwrjZRvafcOruQOYnegkn54c	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q5XIE8	uniprotkb:Q63564	intact:EBI-15348306|ensembl:ENSRNOP00000023037	intact:EBI-9254006	psi-mi:itm2b_rat(display_long)|uniprotkb:Itm2b(gene name)|psi-mi:Itm2b(display_short)|uniprotkb:Immature BRI2(gene name synonym)|uniprotkb:Transmembrane protein BRI(gene name synonym)	psi-mi:sv2b_rat(display_long)|uniprotkb:Sv2b(gene name)|psi-mi:Sv2b(display_short)|uniprotkb:Sv2bb(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Martins et al. (2018)	imex:IM-28469|pubmed:29476059	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26439741|imex:IM-28469-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSRNOG00000016271(gene)|ensembl:ENSRNOT00000023037(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001540"(amyloid-beta binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0010008"(endosome membrane)|go:"GO:0030660"(Golgi-associated vesicle membrane)|go:"GO:0031301"(integral component of organelle membrane)|go:"GO:0042985"(negative regulation of amyloid precursor protein biosynthetic process)|interpro:IPR007084(BRICHOS)|interpro:IPR040145|mint:Q5XIE8|refseq:NP_001006964.1|rgd:620727	interpro:IPR011701(Major facilitator superfamily MFS-1)|interpro:IPR020846|interpro:IPR005828(General substrate transporter)|interpro:IPR005829(Sugar transporter, conserved site)|interpro:IPR022308|mint:Q63564|rgd:619716|refseq:NP_476555.1|interpro:IPR036259|go:"GO:0001504"(neurotransmitter uptake)|go:"GO:0001669"(acrosomal vesicle)|go:"GO:0007268"(chemical synaptic transmission)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0022857"(transmembrane transporter activity)|go:"GO:0030285"(integral component of synaptic vesicle membrane)|go:"GO:0030672"(synaptic vesicle membrane)|go:"GO:0043005"(neuron projection)|go:"GO:0043195"(terminal bouton)	-	-	-	figure legend:st1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10116(rat-brain-cortex)|taxid:10116(Rattus norvegicus brain cortex)	-	2020/10/30	2020/10/30	rogid:DtE+ZXAZKdCMvUW5K+jXQ5bH07M10116	rogid:PnkAiRP4l+Bkf3cK1gDGTPCsT/810116	rigid:3wclwrjZRvafcOruQOYnegkn54c	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q5XIE8	uniprotkb:P09951	intact:EBI-15348306|ensembl:ENSRNOP00000023037	intact:EBI-1638487|uniprotkb:Q9WUX7|ensembl:ENSRNOP00000014250	psi-mi:itm2b_rat(display_long)|uniprotkb:Itm2b(gene name)|psi-mi:Itm2b(display_short)|uniprotkb:Immature BRI2(gene name synonym)|uniprotkb:Transmembrane protein BRI(gene name synonym)	psi-mi:syn1_rat(display_long)|uniprotkb:Syn1(gene name)|psi-mi:Syn1(display_short)|uniprotkb:Synapsin I(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Martins et al. (2018)	imex:IM-28469|pubmed:29476059	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26439741|imex:IM-28469-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSRNOG00000016271(gene)|ensembl:ENSRNOT00000023037(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001540"(amyloid-beta binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0010008"(endosome membrane)|go:"GO:0030660"(Golgi-associated vesicle membrane)|go:"GO:0031301"(integral component of organelle membrane)|go:"GO:0042985"(negative regulation of amyloid precursor protein biosynthetic process)|interpro:IPR007084(BRICHOS)|interpro:IPR040145|mint:Q5XIE8|refseq:NP_001006964.1|rgd:620727	rgd:3797|refseq:NP_001104252.1|refseq:NP_062006.1|ensembl:ENSRNOG00000010365(gene)|ensembl:ENSRNOT00000014250(transcript)|go:"GO:0000795"(synaptonemal complex)|go:"GO:0003779"(actin binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0007269"(neurotransmitter secretion)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0014069"(postsynaptic density)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030424"(axon)|go:"GO:0030425"(dendrite)|go:"GO:0030672"(synaptic vesicle membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0043195"(terminal bouton)|go:"GO:0043229"(intracellular organelle)|go:"GO:0045202"(synapse)|go:"GO:0048306"(calcium-dependent protein binding)|go:"GO:0048666"(neuron development)|go:"GO:0048786"(presynaptic active zone)|go:"GO:0050808"(synapse organization)|go:"GO:0097091"(synaptic vesicle clustering)|go:"GO:0098685"(Schaffer collateral - CA1 synapse)|go:"GO:0098693"(regulation of synaptic vesicle cycle)|go:"GO:0098793"(presynapse)|go:"GO:0098850"(extrinsic component of synaptic vesicle membrane)|go:"GO:0098993"(anchored component of synaptic vesicle membrane)|go:"GO:0099504"(synaptic vesicle cycle)|interpro:IPR001359(Synapsin)|interpro:IPR013815(ATP-grasp fold, subdomain 1)|interpro:IPR016185(PreATP-grasp-like fold)|interpro:IPR019735|interpro:IPR019736|interpro:IPR020897|interpro:IPR020898|interpro:IPR028713|mint:P09951|rcsb pdb:1PK8|rcsb pdb:1PX2|reactome:R-RNO-181429|reactome:R-RNO-212676	-	-	-	figure legend:st1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10116(rat-brain-cortex)|taxid:10116(Rattus norvegicus brain cortex)	-	2020/10/30	2020/10/30	rogid:DtE+ZXAZKdCMvUW5K+jXQ5bH07M10116	rogid:2Kokx9XJDZPkBHu140QPqsDpSxw10116	rigid:3wclwrjZRvafcOruQOYnegkn54c	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q5XIE8	uniprotkb:Q63965	intact:EBI-15348306|ensembl:ENSRNOP00000023037	intact:EBI-918690	psi-mi:itm2b_rat(display_long)|uniprotkb:Itm2b(gene name)|psi-mi:Itm2b(display_short)|uniprotkb:Immature BRI2(gene name synonym)|uniprotkb:Transmembrane protein BRI(gene name synonym)	psi-mi:sfxn1_rat(display_long)|uniprotkb:Tricarboxylate carrier protein(gene name synonym)|uniprotkb:Sfxn1(gene name)|psi-mi:Sfxn1(display_short)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Martins et al. (2018)	imex:IM-28469|pubmed:29476059	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26439741|imex:IM-28469-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSRNOG00000016271(gene)|ensembl:ENSRNOT00000023037(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001540"(amyloid-beta binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0010008"(endosome membrane)|go:"GO:0030660"(Golgi-associated vesicle membrane)|go:"GO:0031301"(integral component of organelle membrane)|go:"GO:0042985"(negative regulation of amyloid precursor protein biosynthetic process)|interpro:IPR007084(BRICHOS)|interpro:IPR040145|mint:Q5XIE8|refseq:NP_001006964.1|rgd:620727	interpro:IPR004686(Tricarboxylate/iron carrier)|rgd:1308482|mint:Q63965|go:"GO:0005739"(mitochondrion)|go:"GO:0006730"(one-carbon metabolic process)|go:"GO:0006826"(iron ion transport)|go:"GO:0015194"(L-serine transmembrane transporter activity)|go:"GO:0015825"(L-serine transport)|go:"GO:0022857"(transmembrane transporter activity)|go:"GO:0022889"(serine transmembrane transporter activity)|go:"GO:0030218"(erythrocyte differentiation)|go:"GO:0031305"(integral component of mitochondrial inner membrane)|go:"GO:0042942"(D-serine transport)|go:"GO:0042945"(D-serine transmembrane transporter activity)|go:"GO:0140300"(serine import into mitochondrion)|go:"GO:1990542"(mitochondrial transmembrane transport)	-	-	-	figure legend:st1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10116(rat-brain-cortex)|taxid:10116(Rattus norvegicus brain cortex)	-	2020/10/30	2020/10/30	rogid:DtE+ZXAZKdCMvUW5K+jXQ5bH07M10116	rogid:oy+pnAKs08HtNyA+d5es2yVFgPY10116	rigid:3wclwrjZRvafcOruQOYnegkn54c	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q5XIE8	uniprotkb:O08875	intact:EBI-15348306|ensembl:ENSRNOP00000023037	intact:EBI-26439688|ensembl:ENSRNOP00000019748	psi-mi:itm2b_rat(display_long)|uniprotkb:Itm2b(gene name)|psi-mi:Itm2b(display_short)|uniprotkb:Immature BRI2(gene name synonym)|uniprotkb:Transmembrane protein BRI(gene name synonym)	psi-mi:dclk1_rat(display_long)|uniprotkb:Dclk1(gene name)|psi-mi:Dclk1(display_short)|uniprotkb:Cpg16(gene name synonym)|uniprotkb:Dcamkl1(gene name synonym)|uniprotkb:Calcium/calmodulin-dependent protein kinase type I-like CPG16(gene name synonym)|uniprotkb:Doublecortin-like and CAM kinase-like 1(gene name synonym)|uniprotkb:Doublecortin-like kinase 1(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Martins et al. (2018)	imex:IM-28469|pubmed:29476059	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26439741|imex:IM-28469-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSRNOG00000016271(gene)|ensembl:ENSRNOT00000023037(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001540"(amyloid-beta binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0010008"(endosome membrane)|go:"GO:0030660"(Golgi-associated vesicle membrane)|go:"GO:0031301"(integral component of organelle membrane)|go:"GO:0042985"(negative regulation of amyloid precursor protein biosynthetic process)|interpro:IPR007084(BRICHOS)|interpro:IPR040145|mint:Q5XIE8|refseq:NP_001006964.1|rgd:620727	ensembl:ENSRNOG00000032922(gene)|ensembl:ENSRNOT00000019748(transcript)|go:"GO:0001764"(neuron migration)|go:"GO:0004672"(protein kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0007409"(axonogenesis)|go:"GO:0007420"(brain development)|go:"GO:0009615"(response to virus)|go:"GO:0014069"(postsynaptic density)|go:"GO:0018105"(peptidyl-serine phosphorylation)|go:"GO:0021952"(central nervous system projection neuron axonogenesis)|go:"GO:0030424"(axon)|go:"GO:0030426"(growth cone)|go:"GO:0030900"(forebrain development)|go:"GO:0048675"(axon extension)|go:"GO:0048812"(neuron projection morphogenesis)|go:"GO:0048813"(dendrite morphogenesis)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:1900181"(negative regulation of protein localization to nucleus)|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|mint:O08875|refseq:NP_445795.1|rgd:68437	-	-	-	figure legend:st1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10116(rat-brain-cortex)|taxid:10116(Rattus norvegicus brain cortex)	-	2020/10/30	2020/10/30	rogid:DtE+ZXAZKdCMvUW5K+jXQ5bH07M10116	rogid:Al+f+qhV/hs3YZhZv7GEdSNfDQM10116	rigid:3wclwrjZRvafcOruQOYnegkn54c	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q5XIE8	uniprotkb:Q9JJM9	intact:EBI-15348306|ensembl:ENSRNOP00000023037	intact:EBI-539712|uniprotkb:Q8R2F7|uniprotkb:Q9JJM8	psi-mi:itm2b_rat(display_long)|uniprotkb:Itm2b(gene name)|psi-mi:Itm2b(display_short)|uniprotkb:Immature BRI2(gene name synonym)|uniprotkb:Transmembrane protein BRI(gene name synonym)	psi-mi:sept5_rat(display_long)|uniprotkb:Septin5(gene name)|psi-mi:Septin5(display_short)|uniprotkb:Cell division control-related protein 1(gene name synonym)|uniprotkb:Peanut-like protein 1(gene name synonym)|uniprotkb:Pnutl1(gene name synonym)|uniprotkb:Sept5(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Martins et al. (2018)	imex:IM-28469|pubmed:29476059	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26439741|imex:IM-28469-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSRNOG00000016271(gene)|ensembl:ENSRNOT00000023037(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001540"(amyloid-beta binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0010008"(endosome membrane)|go:"GO:0030660"(Golgi-associated vesicle membrane)|go:"GO:0031301"(integral component of organelle membrane)|go:"GO:0042985"(negative regulation of amyloid precursor protein biosynthetic process)|interpro:IPR007084(BRICHOS)|interpro:IPR040145|mint:Q5XIE8|refseq:NP_001006964.1|rgd:620727	interpro:IPR027417|interpro:IPR030647|interpro:IPR030379|rgd:621763|interpro:IPR016491(Septin)|mint:Q9JJM9|go:"GO:0005940"(septin ring)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0017157"(regulation of exocytosis)|go:"GO:0005938"(cell cortex)|go:"GO:0019003"(GDP binding)|go:"GO:0019905"(syntaxin binding)|go:"GO:0030534"(adult behavior)|go:"GO:0031105"(septin complex)|go:"GO:0032153"(cell division site)|go:"GO:0032154"(cleavage furrow)|go:"GO:0034613"(cellular protein localization)|go:"GO:0035091"(phosphatidylinositol binding)|go:"GO:0035176"(social behavior)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043195"(terminal bouton)|go:"GO:0043679"(axon terminus)|go:"GO:0044305"(calyx of Held)|go:"GO:0045202"(synapse)|go:"GO:0045921"(positive regulation of exocytosis)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0061640"(cytoskeleton-dependent cytokinesis)|go:"GO:0098793"(presynapse)|go:"GO:0099148"(regulation of synaptic vesicle docking)|go:"GO:0001725"(stress fiber)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005886"(plasma membrane)	-	-	-	figure legend:st1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10116(rat-brain-cortex)|taxid:10116(Rattus norvegicus brain cortex)	-	2020/10/30	2020/10/30	rogid:DtE+ZXAZKdCMvUW5K+jXQ5bH07M10116	rogid:bgzs8rx9e+Yn5zYxczLQYJ11i9g10116	rigid:3wclwrjZRvafcOruQOYnegkn54c	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q5XIE8	uniprotkb:Q3B7K9	intact:EBI-15348306|ensembl:ENSRNOP00000023037	intact:EBI-26439678|ensembl:ENSRNOP00000035622	psi-mi:itm2b_rat(display_long)|uniprotkb:Itm2b(gene name)|psi-mi:Itm2b(display_short)|uniprotkb:Immature BRI2(gene name synonym)|uniprotkb:Transmembrane protein BRI(gene name synonym)	psi-mi:run3b_rat(display_long)|uniprotkb:Rundc3b(gene name)|psi-mi:Rundc3b(display_short)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Martins et al. (2018)	imex:IM-28469|pubmed:29476059	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26439741|imex:IM-28469-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSRNOG00000016271(gene)|ensembl:ENSRNOT00000023037(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001540"(amyloid-beta binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0010008"(endosome membrane)|go:"GO:0030660"(Golgi-associated vesicle membrane)|go:"GO:0031301"(integral component of organelle membrane)|go:"GO:0042985"(negative regulation of amyloid precursor protein biosynthetic process)|interpro:IPR007084(BRICHOS)|interpro:IPR040145|mint:Q5XIE8|refseq:NP_001006964.1|rgd:620727	ensembl:ENSRNOG00000008463(gene)|ensembl:ENSRNOT00000030224(transcript)|interpro:IPR004012(RUN)|interpro:IPR037213|mint:Q3B7K9|refseq:NP_001040581.1|rgd:1587590	-	-	-	figure legend:st1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10116(rat-brain-cortex)|taxid:10116(Rattus norvegicus brain cortex)	-	2020/10/30	2020/10/30	rogid:DtE+ZXAZKdCMvUW5K+jXQ5bH07M10116	rogid:mRwxzxsso8OBQr9Y10RTN3nHF4Q10116	rigid:3wclwrjZRvafcOruQOYnegkn54c	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q5XIE8	uniprotkb:Q6AXX6	intact:EBI-15348306|ensembl:ENSRNOP00000023037	intact:EBI-15185964|ensembl:ENSRNOP00000014819|uniprotkb:P85300	psi-mi:itm2b_rat(display_long)|uniprotkb:Itm2b(gene name)|psi-mi:Itm2b(display_short)|uniprotkb:Immature BRI2(gene name synonym)|uniprotkb:Transmembrane protein BRI(gene name synonym)	psi-mi:pxl2a_rat(display_long)|uniprotkb:Prxl2a(gene name)|psi-mi:Prxl2a(display_short)|uniprotkb:Fam213a(gene name synonym)|uniprotkb:Pamm(gene name synonym)|uniprotkb:Peroxiredoxin-like 2 activated in M-CSF stimulated monocytes(gene name synonym)|uniprotkb:Shp1(gene name synonym)|uniprotkb:Sperm head protein 1(gene name synonym)|uniprotkb:Redox-regulatory protein FAM213A(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Martins et al. (2018)	imex:IM-28469|pubmed:29476059	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26439741|imex:IM-28469-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSRNOG00000016271(gene)|ensembl:ENSRNOT00000023037(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001540"(amyloid-beta binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0010008"(endosome membrane)|go:"GO:0030660"(Golgi-associated vesicle membrane)|go:"GO:0031301"(integral component of organelle membrane)|go:"GO:0042985"(negative regulation of amyloid precursor protein biosynthetic process)|interpro:IPR007084(BRICHOS)|interpro:IPR040145|mint:Q5XIE8|refseq:NP_001006964.1|rgd:620727	ensembl:ENSRNOG00000011140(gene)|ensembl:ENSRNOT00000014819(transcript)|go:"GO:0005576"(extracellular region)|go:"GO:0005737"(cytoplasm)|go:"GO:0016209"(antioxidant activity)|interpro:IPR032801|interpro:IPR032802|interpro:IPR036249|mint:Q6AXX6|go:"GO:0045670"(regulation of osteoclast differentiation)|refseq:NP_001014162.1|refseq:XP_006252853.1|rgd:1309676	-	-	-	figure legend:st1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10116(rat-brain-cortex)|taxid:10116(Rattus norvegicus brain cortex)	-	2020/10/30	2020/10/30	rogid:DtE+ZXAZKdCMvUW5K+jXQ5bH07M10116	rogid:Tnbl3GNIUDyvJ64sU2mgQxM/llc10116	rigid:3wclwrjZRvafcOruQOYnegkn54c	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q5XIE8	uniprotkb:P62824	intact:EBI-15348306|ensembl:ENSRNOP00000023037	intact:EBI-16220903|ensembl:ENSRNOP00000015871|ensembl:ENSRNOP00000073277|uniprotkb:Q62858|uniprotkb:Q62974|uniprotkb:Q63482|uniprotkb:Q9CXQ1	psi-mi:itm2b_rat(display_long)|uniprotkb:Itm2b(gene name)|psi-mi:Itm2b(display_short)|uniprotkb:Immature BRI2(gene name synonym)|uniprotkb:Transmembrane protein BRI(gene name synonym)	psi-mi:rab3c_rat(display_long)|uniprotkb:Rab3c(gene name)|psi-mi:Rab3c(display_short)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Martins et al. (2018)	imex:IM-28469|pubmed:29476059	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26439741|imex:IM-28469-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSRNOG00000016271(gene)|ensembl:ENSRNOT00000023037(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001540"(amyloid-beta binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0010008"(endosome membrane)|go:"GO:0030660"(Golgi-associated vesicle membrane)|go:"GO:0031301"(integral component of organelle membrane)|go:"GO:0042985"(negative regulation of amyloid precursor protein biosynthetic process)|interpro:IPR007084(BRICHOS)|interpro:IPR040145|mint:Q5XIE8|refseq:NP_001006964.1|rgd:620727	ensembl:ENSRNOG00000011623(gene)|ensembl:ENSRNOT00000015871(transcript)|ensembl:ENSRNOT00000086851(transcript)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005768"(endosome)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006904"(vesicle docking involved in exocytosis)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0009306"(protein secretion)|go:"GO:0017157"(regulation of exocytosis)|go:"GO:0019882"(antigen processing and presentation)|go:"GO:0030742"(GTP-dependent protein binding)|go:"GO:0031489"(myosin V binding)|go:"GO:0031982"(vesicle)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0098993"(anchored component of synaptic vesicle membrane)|interpro:IPR001806(Ras GTPase)|interpro:IPR005225(Small GTP-binding protein)|interpro:IPR027417|interpro:IPR037872|mint:P62824|reactome:R-RNO-8873719|refseq:NP_598220.1|rgd:620923	-	-	-	figure legend:st1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10116(rat-brain-cortex)|taxid:10116(Rattus norvegicus brain cortex)	-	2020/10/30	2020/10/30	rogid:DtE+ZXAZKdCMvUW5K+jXQ5bH07M10116	rogid:F0BXS2E7Unlk+uNhGFX8SXRN9hA10116	rigid:3wclwrjZRvafcOruQOYnegkn54c	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q5XIE8	uniprotkb:P35281	intact:EBI-15348306|ensembl:ENSRNOP00000023037	intact:EBI-917314	psi-mi:itm2b_rat(display_long)|uniprotkb:Itm2b(gene name)|psi-mi:Itm2b(display_short)|uniprotkb:Immature BRI2(gene name synonym)|uniprotkb:Transmembrane protein BRI(gene name synonym)	psi-mi:rab10_rat(display_long)|uniprotkb:Rab10(gene name)|psi-mi:Rab10(display_short)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Martins et al. (2018)	imex:IM-28469|pubmed:29476059	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26439741|imex:IM-28469-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSRNOG00000016271(gene)|ensembl:ENSRNOT00000023037(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001540"(amyloid-beta binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0010008"(endosome membrane)|go:"GO:0030660"(Golgi-associated vesicle membrane)|go:"GO:0031301"(integral component of organelle membrane)|go:"GO:0042985"(negative regulation of amyloid precursor protein biosynthetic process)|interpro:IPR007084(BRICHOS)|interpro:IPR040145|mint:Q5XIE8|refseq:NP_001006964.1|rgd:620727	interpro:IPR005225(Small GTP-binding protein)|interpro:IPR001806(Ras GTPase)|rgd:620879|interpro:IPR027417|mint:P35281|go:"GO:0003925"(G protein activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005768"(endosome)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0005886"(plasma membrane)|go:"GO:0005929"(cilium)|go:"GO:0006893"(Golgi to plasma membrane transport)|go:"GO:0006904"(vesicle docking involved in exocytosis)|go:"GO:0007409"(axonogenesis)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0009306"(protein secretion)|go:"GO:0016020"(membrane)|go:"GO:0016192"(vesicle-mediated transport)|go:"GO:0016197"(endosomal transport)|go:"GO:0017157"(regulation of exocytosis)|go:"GO:0019003"(GDP binding)|go:"GO:0019882"(antigen processing and presentation)|go:"GO:0030670"(phagocytic vesicle membrane)|go:"GO:0030859"(polarized epithelial cell differentiation)|go:"GO:0031489"(myosin V binding)|go:"GO:0032593"(insulin-responsive compartment)|go:"GO:0032869"(cellular response to insulin stimulus)|go:"GO:0043001"(Golgi to plasma membrane protein transport)|go:"GO:0045055"(regulated exocytosis)|go:"GO:0045200"(establishment of neuroblast polarity)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051021"(GDP-dissociation inhibitor binding)|go:"GO:0055037"(recycling endosome)|go:"GO:0055038"(recycling endosome membrane)|go:"GO:0070382"(exocytic vesicle)|go:"GO:0071236"(cellular response to antibiotic)|go:"GO:0071782"(endoplasmic reticulum tubular network)|go:"GO:0071786"(endoplasmic reticulum tubular network organization)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0090150"(establishment of protein localization to membrane)|go:"GO:0097051"(establishment of protein localization to endoplasmic reticulum membrane)|go:"GO:0098993"(anchored component of synaptic vesicle membrane)|go:"GO:1903361"(protein localization to basolateral plasma membrane)|reactome:R-RNO-6798695|reactome:R-RNO-8873719|reactome:R-RNO-8876198	-	-	-	figure legend:st1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10116(rat-brain-cortex)|taxid:10116(Rattus norvegicus brain cortex)	-	2020/10/30	2020/10/30	rogid:DtE+ZXAZKdCMvUW5K+jXQ5bH07M10116	rogid:QBab92qaS/E5P8CwghgaSofYfu410116	rigid:3wclwrjZRvafcOruQOYnegkn54c	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q5XIE8	uniprotkb:P47709	intact:EBI-15348306|ensembl:ENSRNOP00000023037	intact:EBI-1027524	psi-mi:itm2b_rat(display_long)|uniprotkb:Itm2b(gene name)|psi-mi:Itm2b(display_short)|uniprotkb:Immature BRI2(gene name synonym)|uniprotkb:Transmembrane protein BRI(gene name synonym)	psi-mi:rp3a_rat(display_long)|uniprotkb:Rph3a(gene name)|psi-mi:Rph3a(display_short)|uniprotkb:Exophilin-1(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Martins et al. (2018)	imex:IM-28469|pubmed:29476059	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26439741|imex:IM-28469-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSRNOG00000016271(gene)|ensembl:ENSRNOT00000023037(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001540"(amyloid-beta binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0010008"(endosome membrane)|go:"GO:0030660"(Golgi-associated vesicle membrane)|go:"GO:0031301"(integral component of organelle membrane)|go:"GO:0042985"(negative regulation of amyloid precursor protein biosynthetic process)|interpro:IPR007084(BRICHOS)|interpro:IPR040145|mint:Q5XIE8|refseq:NP_001006964.1|rgd:620727	go:"GO:0005509"(calcium ion binding)|go:"GO:0005543"(phospholipid binding)|go:"GO:0005544"(calcium-dependent phospholipid binding)|go:"GO:0005546"(phosphatidylinositol-4,5-bisphosphate binding)|go:"GO:0005829"(cytosol)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0007420"(brain development)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0008270"(zinc ion binding)|go:"GO:0008430"(selenium binding)|go:"GO:0019898"(extrinsic component of membrane)|go:"GO:0030141"(secretory granule)|go:"GO:0030672"(synaptic vesicle membrane)|go:"GO:0031267"(small GTPase binding)|go:"GO:0031594"(neuromuscular junction)|go:"GO:0032991"(protein-containing complex)|go:"GO:0042301"(phosphate ion binding)|go:"GO:0043005"(neuron projection)|go:"GO:0043197"(dendritic spine)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045202"(synapse)|go:"GO:0045211"(postsynaptic membrane)|go:"GO:0061669"(spontaneous neurotransmitter secretion)|go:"GO:0070679"(inositol 1,4,5 trisphosphate binding)|go:"GO:0097061"(dendritic spine organization)|go:"GO:0098850"(extrinsic component of synaptic vesicle membrane)|go:"GO:0098981"(cholinergic synapse)|go:"GO:2000310"(regulation of NMDA receptor activity)|rcsb pdb:1ZBD|rcsb pdb:2CHD|rcsb pdb:2CM5|rcsb pdb:2CM6|rcsb pdb:3RPB|rcsb pdb:4LT7|rcsb pdb:4NP9|rcsb pdb:4NS0|rcsb pdb:5LO8|rcsb pdb:5LOB|rcsb pdb:5LOW|rgd:620073|refseq:NP_598202.1|interpro:IPR000008(C2 calcium-dependent membrane targeting)|interpro:IPR010911(Rab-binding)|interpro:IPR001565(Synaptotagmin)|interpro:IPR017455(Zinc finger, FYVE-related)|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR028698|mint:P47709|interpro:IPR035892|interpro:IPR041282|interpro:IPR043566	-	-	-	figure legend:st1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10116(rat-brain-cortex)|taxid:10116(Rattus norvegicus brain cortex)	-	2020/10/30	2020/10/30	rogid:DtE+ZXAZKdCMvUW5K+jXQ5bH07M10116	rogid:riq0dOgXETaODPbUSvUER63L6jU10116	rigid:3wclwrjZRvafcOruQOYnegkn54c	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q5XIE8	uniprotkb:P11980	intact:EBI-15348306|ensembl:ENSRNOP00000023037	intact:EBI-916419|uniprotkb:P11981|ensembl:ENSRNOP00000015331	psi-mi:itm2b_rat(display_long)|uniprotkb:Itm2b(gene name)|psi-mi:Itm2b(display_short)|uniprotkb:Immature BRI2(gene name synonym)|uniprotkb:Transmembrane protein BRI(gene name synonym)	psi-mi:kpym_rat(display_long)|uniprotkb:Pkm(gene name)|psi-mi:Pkm(display_short)|uniprotkb:Pkm2(gene name synonym)|uniprotkb:Pykm(gene name synonym)|uniprotkb:Pyruvate kinase muscle isozyme(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Martins et al. (2018)	imex:IM-28469|pubmed:29476059	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26439741|imex:IM-28469-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSRNOG00000016271(gene)|ensembl:ENSRNOT00000023037(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001540"(amyloid-beta binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0010008"(endosome membrane)|go:"GO:0030660"(Golgi-associated vesicle membrane)|go:"GO:0031301"(integral component of organelle membrane)|go:"GO:0042985"(negative regulation of amyloid precursor protein biosynthetic process)|interpro:IPR007084(BRICHOS)|interpro:IPR040145|mint:Q5XIE8|refseq:NP_001006964.1|rgd:620727	ensembl:ENSRNOG00000011329(gene)|ensembl:ENSRNOT00000015332(transcript)|go:"GO:0000287"(magnesium ion binding)|go:"GO:0001666"(response to hypoxia)|go:"GO:0001889"(liver development)|go:"GO:0003729"(mRNA binding)|go:"GO:0004743"(pyruvate kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005791"(rough endoplasmic reticulum)|go:"GO:0005929"(cilium)|go:"GO:0006006"(glucose metabolic process)|go:"GO:0006096"(glycolytic process)|go:"GO:0006754"(ATP biosynthetic process)|go:"GO:0007584"(response to nutrient)|go:"GO:0009629"(response to gravity)|go:"GO:0010033"(response to organic substance)|go:"GO:0012501"(programmed cell death)|go:"GO:0014870"(response to muscle inactivity)|go:"GO:0016301"(kinase activity)|go:"GO:0030955"(potassium ion binding)|go:"GO:0031100"(animal organ regeneration)|go:"GO:0032868"(response to insulin)|go:"GO:0032869"(cellular response to insulin stimulus)|go:"GO:0042802"(identical protein binding)|go:"GO:0042866"(pyruvate biosynthetic process)|go:"GO:0043403"(skeletal muscle tissue regeneration)|go:"GO:0043531"(ADP binding)|go:"GO:0070324"(thyroid hormone binding)|go:"GO:1902912"(pyruvate kinase complex)|go:"GO:1903672"(positive regulation of sprouting angiogenesis)|go:"GO:2000767"(positive regulation of cytoplasmic translation)|interpro:IPR001697(Pyruvate kinase)|interpro:IPR011037(Pyruvate kinase, beta-barrel-like)|interpro:IPR015793(Pyruvate kinase, barrel)|interpro:IPR015795(Pyruvate kinase, C-terminal-like)|interpro:IPR015806(Pyruvate kinase, beta-barrel)|interpro:IPR015813(Pyruvate/Phosphoenolpyruvate kinase, catalytic core)|interpro:IPR018209|interpro:IPR036918|interpro:IPR040442|mint:P11980|refseq:XP_006243250.2|rgd:3337|refseq:NP_445749.1	-	-	-	figure legend:st1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10116(rat-brain-cortex)|taxid:10116(Rattus norvegicus brain cortex)	-	2020/10/30	2020/10/30	rogid:DtE+ZXAZKdCMvUW5K+jXQ5bH07M10116	rogid:GYxco5bbxaUXWMal0+5tWXFouDc10116	rigid:3wclwrjZRvafcOruQOYnegkn54c	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q5XIE8	uniprotkb:O35244	intact:EBI-15348306|ensembl:ENSRNOP00000023037	intact:EBI-915490|ensembl:ENSRNOP00000030323	psi-mi:itm2b_rat(display_long)|uniprotkb:Itm2b(gene name)|psi-mi:Itm2b(display_short)|uniprotkb:Immature BRI2(gene name synonym)|uniprotkb:Transmembrane protein BRI(gene name synonym)	psi-mi:prdx6_rat(display_long)|uniprotkb:Antioxidant protein 2(gene name synonym)|uniprotkb:1-Cys peroxiredoxin(gene name synonym)|uniprotkb:Acidic calcium-independent phospholipase A2(gene name synonym)|uniprotkb:Non-selenium glutathione peroxidase(gene name synonym)|uniprotkb:Thiol-specific antioxidant protein(gene name synonym)|uniprotkb:Prdx6(gene name)|psi-mi:Prdx6(display_short)|uniprotkb:Aipla2(gene name synonym)|uniprotkb:Aop2(gene name synonym)|uniprotkb:Tsa(gene name synonym)|uniprotkb:Glutathione-dependent peroxiredoxin(gene name synonym)|uniprotkb:Lysophosphatidylcholine acyltransferase 5(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Martins et al. (2018)	imex:IM-28469|pubmed:29476059	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26439741|imex:IM-28469-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSRNOG00000016271(gene)|ensembl:ENSRNOT00000023037(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001540"(amyloid-beta binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0010008"(endosome membrane)|go:"GO:0030660"(Golgi-associated vesicle membrane)|go:"GO:0031301"(integral component of organelle membrane)|go:"GO:0042985"(negative regulation of amyloid precursor protein biosynthetic process)|interpro:IPR007084(BRICHOS)|interpro:IPR040145|mint:Q5XIE8|refseq:NP_001006964.1|rgd:620727	rgd:71005|refseq:NP_446028.1|ensembl:ENSRNOG00000002896(gene)|ensembl:ENSRNOT00000034583(transcript)|go:"GO:0000302"(response to reactive oxygen species)|go:"GO:0004601"(peroxidase activity)|go:"GO:0004602"(glutathione peroxidase activity)|go:"GO:0004623"(phospholipase A2 activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005764"(lysosome)|go:"GO:0005829"(cytosol)|go:"GO:0006979"(response to oxidative stress)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032060"(bleb assembly)|go:"GO:0042744"(hydrogen peroxide catabolic process)|go:"GO:0042802"(identical protein binding)|go:"GO:0045454"(cell redox homeostasis)|go:"GO:0046475"(glycerophospholipid catabolic process)|go:"GO:0047184"(1-acylglycerophosphocholine O-acyltransferase activity)|go:"GO:0047499"(calcium-independent phospholipase A2 activity)|go:"GO:0048026"(positive regulation of mRNA splicing, via spliceosome)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051920"(peroxiredoxin activity)|go:"GO:0098869"(cellular oxidant detoxification)|go:"GO:0102567"|go:"GO:0102568"|interpro:IPR000866(Alkyl hydroperoxide reductase/ Thiol specific antioxidant/ Mal allergen)|interpro:IPR013766(Thioredoxin domain)|interpro:IPR019479|interpro:IPR024706|interpro:IPR036249|mint:O35244|reactome:R-RNO-3299685|reactome:R-RNO-6798695	-	-	-	figure legend:st1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10116(rat-brain-cortex)|taxid:10116(Rattus norvegicus brain cortex)	-	2020/10/30	2020/10/30	rogid:DtE+ZXAZKdCMvUW5K+jXQ5bH07M10116	rogid:HbGGY4bUEtG4UTtU/Py7eOaeNJg10116	rigid:3wclwrjZRvafcOruQOYnegkn54c	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q5XIE8	uniprotkb:Q63716	intact:EBI-15348306|ensembl:ENSRNOP00000023037	intact:EBI-918674|ensembl:ENSRNOP00000023132	psi-mi:itm2b_rat(display_long)|uniprotkb:Itm2b(gene name)|psi-mi:Itm2b(display_short)|uniprotkb:Immature BRI2(gene name synonym)|uniprotkb:Transmembrane protein BRI(gene name synonym)	psi-mi:prdx1_rat(display_long)|uniprotkb:Thioredoxin peroxidase 2(gene name synonym)|uniprotkb:Thioredoxin-dependent peroxide reductase 2(gene name synonym)|uniprotkb:Heme-binding 23 kDa protein(gene name synonym)|uniprotkb:HBP23(gene name synonym)|uniprotkb:Prdx1(gene name)|psi-mi:Prdx1(display_short)|uniprotkb:Tdpx2(gene name synonym)|uniprotkb:Thioredoxin-dependent peroxiredoxin 1(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Martins et al. (2018)	imex:IM-28469|pubmed:29476059	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26439741|imex:IM-28469-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSRNOG00000016271(gene)|ensembl:ENSRNOT00000023037(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001540"(amyloid-beta binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0010008"(endosome membrane)|go:"GO:0030660"(Golgi-associated vesicle membrane)|go:"GO:0031301"(integral component of organelle membrane)|go:"GO:0042985"(negative regulation of amyloid precursor protein biosynthetic process)|interpro:IPR007084(BRICHOS)|interpro:IPR040145|mint:Q5XIE8|refseq:NP_001006964.1|rgd:620727	rgd:620039|refseq:NP_476455.1|ensembl:ENSRNOG00000017194(gene)|ensembl:ENSRNOT00000023132(transcript)|go:"GO:0000302"(response to reactive oxygen species)|go:"GO:0000791"(euchromatin)|go:"GO:0004601"(peroxidase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0005782"(peroxisomal matrix)|go:"GO:0005829"(cytosol)|go:"GO:0006979"(response to oxidative stress)|go:"GO:0008283"(cell population proliferation)|go:"GO:0008379"(thioredoxin peroxidase activity)|go:"GO:0019430"(removal of superoxide radicals)|go:"GO:0020037"(heme binding)|go:"GO:0030101"(natural killer cell activation)|go:"GO:0032872"(regulation of stress-activated MAPK cascade)|go:"GO:0034101"(erythrocyte homeostasis)|go:"GO:0042267"(natural killer cell mediated cytotoxicity)|go:"GO:0042744"(hydrogen peroxide catabolic process)|go:"GO:0042802"(identical protein binding)|go:"GO:0045321"(leukocyte activation)|go:"GO:0045454"(cell redox homeostasis)|go:"GO:0051920"(peroxiredoxin activity)|go:"GO:1901222"(regulation of NIK/NF-kappaB signaling)|interpro:IPR000866(Alkyl hydroperoxide reductase/ Thiol specific antioxidant/ Mal allergen)|interpro:IPR013766(Thioredoxin domain)|interpro:IPR019479|interpro:IPR024706|interpro:IPR036249|mint:Q63716|rcsb pdb:1QQ2|rcsb pdb:2Z9S|reactome:R-RNO-3299685|reactome:R-RNO-5628897	-	-	-	figure legend:st1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10116(rat-brain-cortex)|taxid:10116(Rattus norvegicus brain cortex)	-	2020/10/30	2020/10/30	rogid:DtE+ZXAZKdCMvUW5K+jXQ5bH07M10116	rogid:6Yx5rIs6p9cg57ePcRAtiWUM7p010116	rigid:3wclwrjZRvafcOruQOYnegkn54c	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q5XIE8	uniprotkb:O08839	intact:EBI-15348306|ensembl:ENSRNOP00000023037	intact:EBI-80095	psi-mi:itm2b_rat(display_long)|uniprotkb:Itm2b(gene name)|psi-mi:Itm2b(display_short)|uniprotkb:Immature BRI2(gene name synonym)|uniprotkb:Transmembrane protein BRI(gene name synonym)	psi-mi:bin1_rat(display_long)|uniprotkb:Bin1(gene name)|psi-mi:Bin1(display_short)|uniprotkb:Amph2(gene name synonym)|uniprotkb:Amphl(gene name synonym)|uniprotkb:Bridging integrator 1(gene name synonym)|uniprotkb:Amphiphysin-like protein(gene name synonym)|uniprotkb:Amphiphysin II(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Martins et al. (2018)	imex:IM-28469|pubmed:29476059	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26439741|imex:IM-28469-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSRNOG00000016271(gene)|ensembl:ENSRNOT00000023037(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001540"(amyloid-beta binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0010008"(endosome membrane)|go:"GO:0030660"(Golgi-associated vesicle membrane)|go:"GO:0031301"(integral component of organelle membrane)|go:"GO:0042985"(negative regulation of amyloid precursor protein biosynthetic process)|interpro:IPR007084(BRICHOS)|interpro:IPR040145|mint:Q5XIE8|refseq:NP_001006964.1|rgd:620727	go:"GO:0002020"(protease binding)|go:"GO:0005543"(phospholipid binding)|go:"GO:0005634"(nucleus)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005768"(endosome)|go:"GO:0005874"(microtubule)|go:"GO:0005886"(plasma membrane)|go:"GO:0006997"(nucleus organization)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0008333"(endosome to lysosome transport)|go:"GO:0016020"(membrane)|go:"GO:0019828"(aspartic-type endopeptidase inhibitor activity)|go:"GO:0030018"(Z disc)|go:"GO:0030315"(T-tubule)|go:"GO:0030424"(axon)|go:"GO:0030425"(dendrite)|go:"GO:0030838"(positive regulation of actin filament polymerization)|go:"GO:0031674"(I band)|go:"GO:0031982"(vesicle)|go:"GO:0033268"(node of Ranvier)|go:"GO:0033292"(T-tubule organization)|go:"GO:0042692"(muscle cell differentiation)|go:"GO:0042802"(identical protein binding)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043194"(axon initial segment)|go:"GO:0043196"(varicosity)|go:"GO:0043547"(positive regulation of GTPase activity)|go:"GO:0043679"(axon terminus)|go:"GO:0044300"(cerebellar mossy fiber)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045202"(synapse)|go:"GO:0045664"(regulation of neuron differentiation)|go:"GO:0045807"(positive regulation of endocytosis)|go:"GO:0048156"(tau protein binding)|go:"GO:0048488"(synaptic vesicle endocytosis)|go:"GO:0048711"(positive regulation of astrocyte differentiation)|go:"GO:0051015"(actin filament binding)|go:"GO:0051020"(GTPase binding)|go:"GO:0051087"(chaperone binding)|go:"GO:0051647"(nucleus localization)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0060987"(lipid tube)|go:"GO:0060988"(lipid tube assembly)|go:"GO:0070063"(RNA polymerase binding)|go:"GO:0086091"(regulation of heart rate by cardiac conduction)|go:"GO:0098850"(extrinsic component of synaptic vesicle membrane)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:1901380"(negative regulation of potassium ion transmembrane transport)|go:"GO:1902430"(negative regulation of amyloid-beta formation)|go:"GO:1902960"(negative regulation of aspartic-type endopeptidase activity involved in amyloid precursor protein catabolic process)|go:"GO:1904878"(negative regulation of calcium ion transmembrane transport via high voltage-gated calcium channel)|interpro:IPR001452(Src homology-3)|interpro:IPR003005(Amphiphysin)|interpro:IPR003023(Amphiphysin, isoform 2)|interpro:IPR004148(BAR)|interpro:IPR027267|interpro:IPR035471|interpro:IPR036028|rcsb pdb:1BB9|reactome:R-RNO-8856828|go:"GO:1903946"(negative regulation of ventricular cardiac muscle cell action potential)|rgd:621786|refseq:NP_446411.1|mint:O08839|dip:DIP-30979N	-	-	-	figure legend:st1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10116(rat-brain-cortex)|taxid:10116(Rattus norvegicus brain cortex)	-	2020/10/30	2020/10/30	rogid:DtE+ZXAZKdCMvUW5K+jXQ5bH07M10116	rogid:xqcXQWo+FXHjCGGI0Q9agaz9LMk10116	rigid:3wclwrjZRvafcOruQOYnegkn54c	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q5XIE8	uniprotkb:F1LP90	intact:EBI-15348306|ensembl:ENSRNOP00000023037	intact:EBI-21999164	psi-mi:itm2b_rat(display_long)|uniprotkb:Itm2b(gene name)|psi-mi:Itm2b(display_short)|uniprotkb:Immature BRI2(gene name synonym)|uniprotkb:Transmembrane protein BRI(gene name synonym)	psi-mi:mink1_rat(display_long)|uniprotkb:GCK family kinase MiNK(gene name synonym)|uniprotkb:MAPK/ERK kinase kinase kinase 6(gene name synonym)|uniprotkb:Misshapen/NIK-related kinase(gene name synonym)|uniprotkb:Mitogen-activated protein kinase kinase kinase kinase 6(gene name synonym)|uniprotkb:Mink1(gene name)|psi-mi:Mink1(display_short)|uniprotkb:Map4k6(gene name synonym)|uniprotkb:Mink(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Martins et al. (2018)	imex:IM-28469|pubmed:29476059	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26439741|imex:IM-28469-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSRNOG00000016271(gene)|ensembl:ENSRNOT00000023037(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001540"(amyloid-beta binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0010008"(endosome membrane)|go:"GO:0030660"(Golgi-associated vesicle membrane)|go:"GO:0031301"(integral component of organelle membrane)|go:"GO:0042985"(negative regulation of amyloid precursor protein biosynthetic process)|interpro:IPR007084(BRICHOS)|interpro:IPR040145|mint:Q5XIE8|refseq:NP_001006964.1|rgd:620727	interpro:IPR001180(Citron-like)|interpro:IPR011009(Protein kinase-like)|interpro:IPR000719(Protein kinase, core)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR008271(Serine/threonine protein kinase, active site)|rgd:1359135|mint:F1LP90|go:"GO:0000165"(MAPK cascade)|go:"GO:0001952"(regulation of cell-matrix adhesion)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0007268"(chemical synaptic transmission)|go:"GO:0014069"(postsynaptic density)|go:"GO:0022407"(regulation of cell-cell adhesion)|go:"GO:0030334"(regulation of cell migration)|go:"GO:0030424"(axon)|go:"GO:0030425"(dendrite)|go:"GO:0031532"(actin cytoskeleton reorganization)|go:"GO:0032147"(activation of protein kinase activity)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0043408"(regulation of MAPK cascade)|go:"GO:0045060"(negative thymic T cell selection)|go:"GO:0046330"(positive regulation of JNK cascade)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0048812"(neuron projection morphogenesis)|go:"GO:0048813"(dendrite morphogenesis)|go:"GO:0070050"(neuron cellular homeostasis)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:1900745"(positive regulation of p38MAPK cascade)|go:"GO:2000311"(regulation of AMPA receptor activity)|reactome:R-RNO-2559580	-	-	-	figure legend:st1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10116(rat-brain-cortex)|taxid:10116(Rattus norvegicus brain cortex)	-	2020/10/30	2020/10/30	rogid:DtE+ZXAZKdCMvUW5K+jXQ5bH07M10116	rogid:fYUvFtktedoFxUnNJyLwGQu6DLQ10116	rigid:3wclwrjZRvafcOruQOYnegkn54c	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q5XIE8	uniprotkb:Q5M7W5	intact:EBI-15348306|ensembl:ENSRNOP00000023037	intact:EBI-26408505|uniprotkb:Q75NR5|uniprotkb:Q75NR6|ensembl:ENSRNOP00000053011	psi-mi:itm2b_rat(display_long)|uniprotkb:Itm2b(gene name)|psi-mi:Itm2b(display_short)|uniprotkb:Immature BRI2(gene name synonym)|uniprotkb:Transmembrane protein BRI(gene name synonym)	psi-mi:map4_rat(display_long)|uniprotkb:Map4(gene name)|psi-mi:Map4(display_short)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Martins et al. (2018)	imex:IM-28469|pubmed:29476059	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26439741|imex:IM-28469-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSRNOG00000016271(gene)|ensembl:ENSRNOT00000023037(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001540"(amyloid-beta binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0010008"(endosome membrane)|go:"GO:0030660"(Golgi-associated vesicle membrane)|go:"GO:0031301"(integral component of organelle membrane)|go:"GO:0042985"(negative regulation of amyloid precursor protein biosynthetic process)|interpro:IPR007084(BRICHOS)|interpro:IPR040145|mint:Q5XIE8|refseq:NP_001006964.1|rgd:620727	refseq:NP_001019449.1|rgd:1564359|ensembl:ENSRNOG00000020748(gene)|ensembl:ENSRNOT00000056166(transcript)|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0005874"(microtubule)|go:"GO:0005930"(axoneme)|go:"GO:0007052"(mitotic spindle organization)|go:"GO:0008017"(microtubule binding)|go:"GO:0030424"(axon)|go:"GO:0014069"(postsynaptic density)|go:"GO:0031175"(neuron projection development)|go:"GO:0043005"(neuron projection)|go:"GO:0051012"(microtubule sliding)|go:"GO:0051294"(establishment of spindle orientation)|go:"GO:0051301"(cell division)|go:"GO:0072686"(mitotic spindle)|go:"GO:1902856"(negative regulation of non-motile cilium assembly)|interpro:IPR001084(Tubulin-binding Tau protein)|interpro:IPR027323|mint:Q5M7W5	-	-	-	figure legend:st1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10116(rat-brain-cortex)|taxid:10116(Rattus norvegicus brain cortex)	-	2020/10/30	2020/10/30	rogid:DtE+ZXAZKdCMvUW5K+jXQ5bH07M10116	rogid:wJ/zwFbSbQkk3JEQjUQjVIHMtmk10116	rigid:3wclwrjZRvafcOruQOYnegkn54c	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q5XIE8	uniprotkb:P34926	intact:EBI-15348306|ensembl:ENSRNOP00000023037	intact:EBI-631571	psi-mi:itm2b_rat(display_long)|uniprotkb:Itm2b(gene name)|psi-mi:Itm2b(display_short)|uniprotkb:Immature BRI2(gene name synonym)|uniprotkb:Transmembrane protein BRI(gene name synonym)	psi-mi:map1a_rat(display_long)|uniprotkb:Map1a(gene name)|psi-mi:Map1a(display_short)|uniprotkb:Mtap1a(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Martins et al. (2018)	imex:IM-28469|pubmed:29476059	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26439741|imex:IM-28469-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSRNOG00000016271(gene)|ensembl:ENSRNOT00000023037(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001540"(amyloid-beta binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0010008"(endosome membrane)|go:"GO:0030660"(Golgi-associated vesicle membrane)|go:"GO:0031301"(integral component of organelle membrane)|go:"GO:0042985"(negative regulation of amyloid precursor protein biosynthetic process)|interpro:IPR007084(BRICHOS)|interpro:IPR040145|mint:Q5XIE8|refseq:NP_001006964.1|rgd:620727	rgd:3042|refseq:NP_112257.1|go:"GO:0007026"(negative regulation of microtubule depolymerization)|go:"GO:0007409"(axonogenesis)|go:"GO:0007605"(sensory perception of sound)|go:"GO:0007613"(memory)|go:"GO:0008017"(microtubule binding)|go:"GO:0008093"(cytoskeletal anchor activity)|go:"GO:0008306"(associative learning)|go:"GO:0014069"(postsynaptic density)|go:"GO:0015631"(tubulin binding)|go:"GO:0016358"(dendrite development)|go:"GO:0030424"(axon)|go:"GO:0030425"(dendrite)|go:"GO:0031114"(regulation of microtubule depolymerization)|go:"GO:0032435"(negative regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0035255"(ionotropic glutamate receptor binding)|go:"GO:0043005"(neuron projection)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043194"(axon initial segment)|go:"GO:0043198"(dendritic shaft)|go:"GO:0044307"(dendritic branch)|go:"GO:0045202"(synapse)|go:"GO:0045494"(photoreceptor cell maintenance)|go:"GO:0048167"(regulation of synaptic plasticity)|go:"GO:0050882"(voluntary musculoskeletal movement)|go:"GO:0070050"(neuron cellular homeostasis)|go:"GO:0099641"(anterograde axonal protein transport)|go:"GO:0099642"(retrograde axonal protein transport)|go:"GO:0150001"(primary dendrite)|go:"GO:1901588"(dendritic microtubule)|go:"GO:1902817"(negative regulation of protein localization to microtubule)|go:"GO:1903829"(positive regulation of protein localization)|go:"GO:1904115"(axon cytoplasm)|go:"GO:1990535"(neuron projection maintenance)|go:"GO:2000010"(positive regulation of protein localization to cell surface)|interpro:IPR015656(MAP1A)|interpro:IPR026074|interpro:IPR036866|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0001750"(photoreceptor outer segment)|go:"GO:0003779"(actin binding)|go:"GO:0005518"(collagen binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005874"(microtubule)|go:"GO:0005875"(microtubule associated complex)|mint:P34926|dip:DIP-29265N	-	-	-	figure legend:st1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10116(rat-brain-cortex)|taxid:10116(Rattus norvegicus brain cortex)	-	2020/10/30	2020/10/30	rogid:DtE+ZXAZKdCMvUW5K+jXQ5bH07M10116	rogid:KoMmjz9oNsuegJgHeF2bcf+Ybhs10116	rigid:3wclwrjZRvafcOruQOYnegkn54c	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q5XIE8	uniprotkb:P43244	intact:EBI-15348306|ensembl:ENSRNOP00000023037	intact:EBI-16220483|uniprotkb:O35833|uniprotkb:Q5DVW1	psi-mi:itm2b_rat(display_long)|uniprotkb:Itm2b(gene name)|psi-mi:Itm2b(display_short)|uniprotkb:Immature BRI2(gene name synonym)|uniprotkb:Transmembrane protein BRI(gene name synonym)	psi-mi:matr3_rat(display_long)|uniprotkb:Matr3(gene name)|psi-mi:Matr3(display_short)|uniprotkb:Nuclear scaffold protein p130/MAT3(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Martins et al. (2018)	imex:IM-28469|pubmed:29476059	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26439741|imex:IM-28469-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSRNOG00000016271(gene)|ensembl:ENSRNOT00000023037(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001540"(amyloid-beta binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0010008"(endosome membrane)|go:"GO:0030660"(Golgi-associated vesicle membrane)|go:"GO:0031301"(integral component of organelle membrane)|go:"GO:0042985"(negative regulation of amyloid precursor protein biosynthetic process)|interpro:IPR007084(BRICHOS)|interpro:IPR040145|mint:Q5XIE8|refseq:NP_001006964.1|rgd:620727	go:"GO:0001825"(blastocyst formation)|go:"GO:0002218"(activation of innate immune response)|go:"GO:0003170"(heart valve development)|go:"GO:0003281"(ventricular septum development)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0008270"(zinc ion binding)|go:"GO:0010608"(posttranscriptional regulation of gene expression)|go:"GO:0016363"(nuclear matrix)|go:"GO:0035198"(miRNA binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0045087"(innate immune response)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|mint:P43244|rgd:3052|refseq:NP_062022.2|refseq:XP_006254596.1|refseq:XP_017456375.1|refseq:XP_017456376.1|interpro:IPR034928|interpro:IPR034930|interpro:IPR000690(Zinc finger, C2H2-type matrin)|interpro:IPR003604(Zinc finger, U1-type)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR035979	-	-	-	figure legend:st1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10116(rat-brain-cortex)|taxid:10116(Rattus norvegicus brain cortex)	-	2020/10/30	2020/10/30	rogid:DtE+ZXAZKdCMvUW5K+jXQ5bH07M10116	rogid:cIeIMjPK3/Ejwo7M0bBIRomzo+810116	rigid:3wclwrjZRvafcOruQOYnegkn54c	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q5XIE8	uniprotkb:P97829	intact:EBI-15348306|ensembl:ENSRNOP00000023037	intact:EBI-15185922|ensembl:ENSRNOP00000050938|ensembl:ENSRNOP00000071430|uniprotkb:O35294	psi-mi:itm2b_rat(display_long)|uniprotkb:Itm2b(gene name)|psi-mi:Itm2b(display_short)|uniprotkb:Immature BRI2(gene name synonym)|uniprotkb:Transmembrane protein BRI(gene name synonym)	psi-mi:cd47_rat(display_long)|uniprotkb:Integrin-associated protein(gene name synonym)|uniprotkb:Cd47(gene name)|psi-mi:Cd47(display_short)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Martins et al. (2018)	imex:IM-28469|pubmed:29476059	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26439741|imex:IM-28469-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSRNOG00000016271(gene)|ensembl:ENSRNOT00000023037(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001540"(amyloid-beta binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0010008"(endosome membrane)|go:"GO:0030660"(Golgi-associated vesicle membrane)|go:"GO:0031301"(integral component of organelle membrane)|go:"GO:0042985"(negative regulation of amyloid precursor protein biosynthetic process)|interpro:IPR007084(BRICHOS)|interpro:IPR040145|mint:Q5XIE8|refseq:NP_001006964.1|rgd:620727	ensembl:ENSRNOG00000001964(gene)|ensembl:ENSRNOT00000050142(transcript)|ensembl:ENSRNOT00000078434(transcript)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006954"(inflammatory response)|go:"GO:0007229"(integrin-mediated signaling pathway)|go:"GO:0008228"(opsonization)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0009617"(response to bacterium)|go:"GO:0009986"(cell surface)|go:"GO:0016477"(cell migration)|go:"GO:0022409"(positive regulation of cell-cell adhesion)|go:"GO:0032649"(regulation of interferon-gamma production)|go:"GO:0032655"(regulation of interleukin-12 production)|go:"GO:0032675"(regulation of interleukin-6 production)|go:"GO:0032680"(regulation of tumor necrosis factor production)|go:"GO:0045428"(regulation of nitric oxide biosynthetic process)|go:"GO:0050729"(positive regulation of inflammatory response)|go:"GO:0050766"(positive regulation of phagocytosis)|go:"GO:0050870"(positive regulation of T cell activation)|go:"GO:0051496"(positive regulation of stress fiber assembly)|go:"GO:0070053"(thrombospondin receptor activity)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070487"(monocyte aggregation)|go:"GO:0071346"(cellular response to interferon-gamma)|go:"GO:0071347"(cellular response to interleukin-1)|go:"GO:0071349"(cellular response to interleukin-12)|go:"GO:0086080"(protein binding involved in heterotypic cell-cell adhesion)|go:"GO:0098632"(cell-cell adhesion mediator activity)|go:"GO:1904669"(ATP export)|go:"GO:1905450"(negative regulation of Fc-gamma receptor signaling pathway involved in phagocytosis)|go:"GO:2000439"(positive regulation of monocyte extravasation)|interpro:IPR006704(CD47 integrin associated protein)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR013147(CD47 transmembrane)|interpro:IPR013270(CD47 immunoglobulin-like)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR037805|mint:P97829|reactome:R-RNO-202733|reactome:R-RNO-216083|reactome:R-RNO-391160|reactome:R-RNO-6798695|go:"GO:0032653"(regulation of interleukin-10 production)|refseq:NP_062068.1|rgd:2308	-	-	-	figure legend:st1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10116(rat-brain-cortex)|taxid:10116(Rattus norvegicus brain cortex)	-	2020/10/30	2020/10/30	rogid:DtE+ZXAZKdCMvUW5K+jXQ5bH07M10116	rogid:NDbHpeXvgK2ywSf2y9vmcTC0flU10116	rigid:3wclwrjZRvafcOruQOYnegkn54c	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q5XIE8	uniprotkb:Q9WVE9	intact:EBI-15348306|ensembl:ENSRNOP00000023037	intact:EBI-6095170|uniprotkb:Q9WVE1|uniprotkb:F1M823|uniprotkb:D3ZV52|ensembl:ENSRNOP00000044773	psi-mi:itm2b_rat(display_long)|uniprotkb:Itm2b(gene name)|psi-mi:Itm2b(display_short)|uniprotkb:Immature BRI2(gene name synonym)|uniprotkb:Transmembrane protein BRI(gene name synonym)	psi-mi:itsn1_rat(display_long)|uniprotkb:Itsn1(gene name)|psi-mi:Itsn1(display_short)|uniprotkb:Ehsh1(gene name synonym)|uniprotkb:Itsn(gene name synonym)|uniprotkb:EH domain and SH3 domain regulator of endocytosis 1(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Martins et al. (2018)	imex:IM-28469|pubmed:29476059	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26439741|imex:IM-28469-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSRNOG00000016271(gene)|ensembl:ENSRNOT00000023037(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001540"(amyloid-beta binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0010008"(endosome membrane)|go:"GO:0030660"(Golgi-associated vesicle membrane)|go:"GO:0031301"(integral component of organelle membrane)|go:"GO:0042985"(negative regulation of amyloid precursor protein biosynthetic process)|interpro:IPR007084(BRICHOS)|interpro:IPR040145|mint:Q5XIE8|refseq:NP_001006964.1|rgd:620727	rgd:2935|refseq:NP_062100.1|refseq:NP_001129568.1|ensembl:ENSRNOG00000002001(gene)|ensembl:ENSRNOT00000042750(transcript)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0005905"(clathrin-coated pit)|go:"GO:0006887"(exocytosis)|go:"GO:0006897"(endocytosis)|go:"GO:0007264"(small GTPase mediated signal transduction)|go:"GO:0007420"(brain development)|go:"GO:0015031"(protein transport)|go:"GO:0016197"(endosomal transport)|go:"GO:0019209"(kinase activator activity)|go:"GO:0030027"(lamellipodium)|go:"GO:0030139"(endocytic vesicle)|go:"GO:0034613"(cellular protein localization)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043195"(terminal bouton)|go:"GO:0043197"(dendritic spine)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0044305"(calyx of Held)|go:"GO:0045202"(synapse)|go:"GO:0048488"(synaptic vesicle endocytosis)|go:"GO:0051897"(positive regulation of protein kinase B signaling)|go:"GO:0055037"(recycling endosome)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0060124"(positive regulation of growth hormone secretion)|go:"GO:0060999"(positive regulation of dendritic spine development)|go:"GO:0070064"(proline-rich region binding)|go:"GO:0097440"(apical dendrite)|go:"GO:0097708"(intracellular vesicle)|go:"GO:0098833"(presynaptic endocytic zone)|go:"GO:0098871"(postsynaptic actin cytoskeleton)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0150007"(clathrin-dependent synaptic vesicle endocytosis)|go:"GO:1905274"(regulation of modification of postsynaptic actin cytoskeleton)|go:"GO:2001288"(positive regulation of caveolin-mediated endocytosis)|interpro:IPR000008(C2 calcium-dependent membrane targeting)|interpro:IPR000219("Dbl homology (DH) domain")|interpro:IPR000261("EPS15 homology (EH)")|interpro:IPR001331(Guanine-nucleotide dissociation stimulator, CDC24, conserved site)|interpro:IPR001452(Src homology-3)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR002048(Calcium-binding EF-hand)|interpro:IPR011992(EF-Hand type)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR018247|interpro:IPR035892|interpro:IPR035899|interpro:IPR036028|mint:Q9WVE9|rcsb pdb:3HS9|reactome:R-RNO-193648|reactome:R-RNO-3928662|reactome:R-RNO-416482|reactome:R-RNO-8856825|reactome:R-RNO-8856828|reactome:R-RNO-9013148|reactome:R-RNO-9013406|reactome:R-RNO-9013408	-	-	-	figure legend:st1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10116(rat-brain-cortex)|taxid:10116(Rattus norvegicus brain cortex)	-	2020/10/30	2020/10/30	rogid:DtE+ZXAZKdCMvUW5K+jXQ5bH07M10116	rogid:JoCpbC+c8T4fn7jqgQEtPXiYaW810116	rigid:3wclwrjZRvafcOruQOYnegkn54c	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q5XIE8	uniprotkb:Q63416	intact:EBI-15348306|ensembl:ENSRNOP00000023037	intact:EBI-15348287|ensembl:ENSRNOP00000023984	psi-mi:itm2b_rat(display_long)|uniprotkb:Itm2b(gene name)|psi-mi:Itm2b(display_short)|uniprotkb:Immature BRI2(gene name synonym)|uniprotkb:Transmembrane protein BRI(gene name synonym)	psi-mi:itih3_rat(display_long)|uniprotkb:Itih3(gene name)|psi-mi:Itih3(display_short)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Martins et al. (2018)	imex:IM-28469|pubmed:29476059	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26439741|imex:IM-28469-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSRNOG00000016271(gene)|ensembl:ENSRNOT00000023037(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001540"(amyloid-beta binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0010008"(endosome membrane)|go:"GO:0030660"(Golgi-associated vesicle membrane)|go:"GO:0031301"(integral component of organelle membrane)|go:"GO:0042985"(negative regulation of amyloid precursor protein biosynthetic process)|interpro:IPR007084(BRICHOS)|interpro:IPR040145|mint:Q5XIE8|refseq:NP_001006964.1|rgd:620727	interpro:IPR002035(von Willebrand factor, type A)|interpro:IPR010600(Inter-alpha-trypsin inhibitor heavy chain, C-terminal)|ensembl:ENSRNOG00000017689(gene)|ensembl:ENSRNOT00000023984(transcript)|go:"GO:0004867"(serine-type endopeptidase inhibitor activity)|go:"GO:0005576"(extracellular region)|go:"GO:0030212"(hyaluronan metabolic process)|interpro:IPR036465|mint:Q63416|reactome:R-RNO-114608|interpro:IPR013694(Vault protein inter-alpha-trypsin)|refseq:NP_059047.1|rgd:620633	-	-	-	figure legend:st1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10116(rat-brain-cortex)|taxid:10116(Rattus norvegicus brain cortex)	-	2020/10/30	2020/10/30	rogid:DtE+ZXAZKdCMvUW5K+jXQ5bH07M10116	rogid:FYOFGuKPLOm1smHocQOD0RN7Qy810116	rigid:3wclwrjZRvafcOruQOYnegkn54c	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q5XIE8	uniprotkb:D3ZGS3	intact:EBI-15348306|ensembl:ENSRNOP00000023037	intact:EBI-26439631|ensembl:ENSRNOP00000072408	psi-mi:itm2b_rat(display_long)|uniprotkb:Itm2b(gene name)|psi-mi:Itm2b(display_short)|uniprotkb:Immature BRI2(gene name synonym)|uniprotkb:Transmembrane protein BRI(gene name synonym)	psi-mi:ocrl_rat(display_long)|uniprotkb:Ocrl(gene name)|psi-mi:Ocrl(display_short)|uniprotkb:Inositol polyphosphate 5-phosphatase OCRL-1(gene name synonym)|uniprotkb:Phosphatidylinositol 3,4,5-triphosphate 5-phosphatase(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Martins et al. (2018)	imex:IM-28469|pubmed:29476059	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26439741|imex:IM-28469-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSRNOG00000016271(gene)|ensembl:ENSRNOT00000023037(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001540"(amyloid-beta binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0010008"(endosome membrane)|go:"GO:0030660"(Golgi-associated vesicle membrane)|go:"GO:0031301"(integral component of organelle membrane)|go:"GO:0042985"(negative regulation of amyloid precursor protein biosynthetic process)|interpro:IPR007084(BRICHOS)|interpro:IPR040145|mint:Q5XIE8|refseq:NP_001006964.1|rgd:620727	reactome:R-RNO-9013423|reactome:R-RNO-9013409|ensembl:ENSRNOG00000003875(gene)|ensembl:ENSRNOT00000082363(transcript)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0001750"(photoreceptor outer segment)|go:"GO:0004439"(phosphatidylinositol-4,5-bisphosphate 5-phosphatase activity)|go:"GO:0004445"(inositol-polyphosphate 5-phosphatase activity)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005769"(early endosome)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0005886"(plasma membrane)|go:"GO:0005905"(clathrin-coated pit)|go:"GO:0007165"(signal transduction)|go:"GO:0016020"(membrane)|go:"GO:0030136"(clathrin-coated vesicle)|go:"GO:0030670"(phagocytic vesicle membrane)|go:"GO:0031267"(small GTPase binding)|go:"GO:0031901"(early endosome membrane)|go:"GO:0034485"(phosphatidylinositol-3,4,5-trisphosphate 5-phosphatase activity)|go:"GO:0043087"(regulation of GTPase activity)|go:"GO:0046855"(inositol phosphate dephosphorylation)|go:"GO:0046856"(phosphatidylinositol dephosphorylation)|go:"GO:0052658"(inositol-1,4,5-trisphosphate 5-phosphatase activity)|go:"GO:0052659"(inositol-1,3,4,5-tetrakisphosphate 5-phosphatase activity)|go:"GO:0052745"(inositol phosphate phosphatase activity)|go:"GO:0060271"(cilium assembly)|interpro:IPR000198(RhoGAP)|interpro:IPR000300(Inositol polyphosphate related phosphatase)|interpro:IPR005135(Endonuclease/exonuclease/phosphatase)|interpro:IPR008936(Rho GTPase activation protein)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR031995|interpro:IPR036691|interpro:IPR037787|interpro:IPR037793|mint:D3ZGS3|reactome:R-RNO-1660499|reactome:R-RNO-1660514|reactome:R-RNO-1855183|reactome:R-RNO-1855204|reactome:R-RNO-432722|reactome:R-RNO-8856828|rgd:1594526	-	-	-	figure legend:st1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10116(rat-brain-cortex)|taxid:10116(Rattus norvegicus brain cortex)	-	2020/10/30	2020/10/30	rogid:DtE+ZXAZKdCMvUW5K+jXQ5bH07M10116	rogid:Gg8sTYtHO1a00q+kPNFzx1/8Os410116	rigid:3wclwrjZRvafcOruQOYnegkn54c	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q5XIE8	uniprotkb:P20761	intact:EBI-15348306|ensembl:ENSRNOP00000023037	intact:EBI-5747204|ensembl:ENSRNOP00000044037	psi-mi:itm2b_rat(display_long)|uniprotkb:Itm2b(gene name)|psi-mi:Itm2b(display_short)|uniprotkb:Immature BRI2(gene name synonym)|uniprotkb:Transmembrane protein BRI(gene name synonym)	psi-mi:igg2b_rat(display_long)|uniprotkb:Igh-1a(gene name)|psi-mi:Igh-1a(display_short)|uniprotkb:Immunoglobulin heavy chain 1a(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Martins et al. (2018)	imex:IM-28469|pubmed:29476059	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26439741|imex:IM-28469-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSRNOG00000016271(gene)|ensembl:ENSRNOT00000023037(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001540"(amyloid-beta binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0010008"(endosome membrane)|go:"GO:0030660"(Golgi-associated vesicle membrane)|go:"GO:0031301"(integral component of organelle membrane)|go:"GO:0042985"(negative regulation of amyloid precursor protein biosynthetic process)|interpro:IPR007084(BRICHOS)|interpro:IPR040145|mint:Q5XIE8|refseq:NP_001006964.1|rgd:620727	rgd:1305720|ensembl:ENSRNOG00000048402(gene)|ensembl:ENSRNOT00000045874(transcript)|go:"GO:0003823"(antigen binding)|go:"GO:0006910"(phagocytosis, recognition)|go:"GO:0006911"(phagocytosis, engulfment)|go:"GO:0006958"(complement activation, classical pathway)|go:"GO:0009897"(external side of plasma membrane)|go:"GO:0034987"(immunoglobulin receptor binding)|go:"GO:0042571"(immunoglobulin complex, circulating)|go:"GO:0042742"(defense response to bacterium)|go:"GO:0045087"(innate immune response)|go:"GO:0050853"(B cell receptor signaling pathway)|go:"GO:0050871"(positive regulation of B cell activation)|interpro:IPR003006(Immunoglobulin/major histocompatibility complex, conserved site)|interpro:IPR003597(Immunoglobulin C1-set)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR036179|mint:P20761|rcsb pdb:1C5D|rcsb pdb:2ARJ|rcsb pdb:3B9K|rcsb pdb:1BFO	-	-	-	figure legend:st1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10116(rat-brain-cortex)|taxid:10116(Rattus norvegicus brain cortex)	-	2020/10/30	2020/10/30	rogid:DtE+ZXAZKdCMvUW5K+jXQ5bH07M10116	rogid:YP3+ZkBaG+Trma6Rnzpb8qwV8xg10116	rigid:3wclwrjZRvafcOruQOYnegkn54c	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q5XIE8	uniprotkb:P0C0S7	intact:EBI-15348306|ensembl:ENSRNOP00000023037	intact:EBI-26439581|uniprotkb:P17317|uniprotkb:Q5U5H6	psi-mi:itm2b_rat(display_long)|uniprotkb:Itm2b(gene name)|psi-mi:Itm2b(display_short)|uniprotkb:Immature BRI2(gene name synonym)|uniprotkb:Transmembrane protein BRI(gene name synonym)	psi-mi:h2az_rat(display_long)|uniprotkb:H2az1(gene name)|psi-mi:H2az1(display_short)|uniprotkb:H2afz(gene name synonym)|uniprotkb:H2az(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Martins et al. (2018)	imex:IM-28469|pubmed:29476059	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26439741|imex:IM-28469-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSRNOG00000016271(gene)|ensembl:ENSRNOT00000023037(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001540"(amyloid-beta binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0010008"(endosome membrane)|go:"GO:0030660"(Golgi-associated vesicle membrane)|go:"GO:0031301"(integral component of organelle membrane)|go:"GO:0042985"(negative regulation of amyloid precursor protein biosynthetic process)|interpro:IPR007084(BRICHOS)|interpro:IPR040145|mint:Q5XIE8|refseq:NP_001006964.1|rgd:620727	reactome:R-RNO-201722|reactome:R-RNO-212300|reactome:R-RNO-2299718|reactome:R-RNO-2559580|reactome:R-RNO-2559582|reactome:R-RNO-2559586|reactome:R-RNO-427359|reactome:R-RNO-427413|reactome:R-RNO-5250924|reactome:R-RNO-5578749|reactome:R-RNO-5625886|reactome:R-RNO-606279|reactome:R-RNO-73728|reactome:R-RNO-73772|reactome:R-RNO-8936459|reactome:R-RNO-9018519|reactome:R-RNO-9670095|reactome:R-RNO-171306|go:"GO:0000786"(nucleosome)|go:"GO:0000791"(euchromatin)|go:"GO:0000792"(heterochromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000979"(RNA polymerase II core promoter sequence-specific DNA binding)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0006342"|go:"GO:0031490"(chromatin DNA binding)|go:"GO:0031492"(nucleosomal DNA binding)|go:"GO:0032869"(cellular response to insulin stimulus)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0071392"(cellular response to estradiol stimulus)|reactome:R-RNO-110330|reactome:R-RNO-110331|mint:P0C0S7|refseq:NP_073165.1|interpro:IPR009072(Histone-fold)|interpro:IPR002119(Histone H2A)|interpro:IPR007125(Histone core)|interpro:IPR032454|interpro:IPR032458|rgd:621464	-	-	-	figure legend:st1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10116(rat-brain-cortex)|taxid:10116(Rattus norvegicus brain cortex)	-	2020/10/30	2020/10/30	rogid:DtE+ZXAZKdCMvUW5K+jXQ5bH07M10116	rogid:0FrzM1TXlduSQ0NNVl0C9uqCUGI10116	rigid:3wclwrjZRvafcOruQOYnegkn54c	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q5XIE8	uniprotkb:P05708	intact:EBI-15348306|ensembl:ENSRNOP00000023037	intact:EBI-2255913	psi-mi:itm2b_rat(display_long)|uniprotkb:Itm2b(gene name)|psi-mi:Itm2b(display_short)|uniprotkb:Immature BRI2(gene name synonym)|uniprotkb:Transmembrane protein BRI(gene name synonym)	psi-mi:hxk1_rat(display_long)|uniprotkb:Hk1(gene name)|psi-mi:Hk1(display_short)|uniprotkb:Hexokinase type I(gene name synonym)|uniprotkb:Brain form hexokinase(gene name synonym)|uniprotkb:Hexokinase-A(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Martins et al. (2018)	imex:IM-28469|pubmed:29476059	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26439741|imex:IM-28469-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSRNOG00000016271(gene)|ensembl:ENSRNOT00000023037(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001540"(amyloid-beta binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0010008"(endosome membrane)|go:"GO:0030660"(Golgi-associated vesicle membrane)|go:"GO:0031301"(integral component of organelle membrane)|go:"GO:0042985"(negative regulation of amyloid precursor protein biosynthetic process)|interpro:IPR007084(BRICHOS)|interpro:IPR040145|mint:Q5XIE8|refseq:NP_001006964.1|rgd:620727	rgd:2796|refseq:NP_036866.1|interpro:IPR001312(Hexokinase)|interpro:IPR022673|interpro:IPR019807|interpro:IPR022672|interpro:IPR043129|mint:P05708|go:"GO:0001666"(response to hypoxia)|go:"GO:0001678"(cellular glucose homeostasis)|go:"GO:0002720"(positive regulation of cytokine production involved in immune response)|go:"GO:0002931"(response to ischemia)|go:"GO:0004340"(glucokinase activity)|go:"GO:0004396"(hexokinase activity)|go:"GO:0004672"(protein kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005536"(glucose binding)|go:"GO:0005739"(mitochondrion)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005829"(cytosol)|go:"GO:0005901"(caveola)|go:"GO:0006002"(fructose 6-phosphate metabolic process)|go:"GO:0006013"(mannose metabolic process)|go:"GO:0006096"(glycolytic process)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0006954"(inflammatory response)|go:"GO:0008865"(fructokinase activity)|go:"GO:0009741"(response to brassinosteroid)|go:"GO:0010359"(regulation of anion channel activity)|go:"GO:0018105"(peptidyl-serine phosphorylation)|go:"GO:0018107"(peptidyl-threonine phosphorylation)|go:"GO:0018108"(peptidyl-tyrosine phosphorylation)|go:"GO:0019158"(mannokinase activity)|go:"GO:0032731"(positive regulation of interleukin-1 beta production)|go:"GO:0032991"(protein-containing complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0042834"(peptidoglycan binding)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045087"(innate immune response)|go:"GO:0045121"(membrane raft)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0046835"(carbohydrate phosphorylation)|go:"GO:0047931"(glucosamine kinase activity)|go:"GO:0051156"(glucose 6-phosphate metabolic process)|go:"GO:0072655"(establishment of protein localization to mitochondrion)|go:"GO:0072656"(maintenance of protein location in mitochondrion)|go:"GO:1901986"(response to ketamine)|rcsb pdb:1BG3|reactome:R-RNO-70171	-	-	-	figure legend:st1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10116(rat-brain-cortex)|taxid:10116(Rattus norvegicus brain cortex)	-	2020/10/30	2020/10/30	rogid:DtE+ZXAZKdCMvUW5K+jXQ5bH07M10116	rogid:Qr89EiLOcvIkO2EN+U+iWjMybSc10116	rigid:3wclwrjZRvafcOruQOYnegkn54c	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q5XIE8	uniprotkb:P53534	intact:EBI-15348306|ensembl:ENSRNOP00000023037	intact:EBI-2696349	psi-mi:itm2b_rat(display_long)|uniprotkb:Itm2b(gene name)|psi-mi:Itm2b(display_short)|uniprotkb:Immature BRI2(gene name synonym)|uniprotkb:Transmembrane protein BRI(gene name synonym)	psi-mi:pygb_rat(display_long)|uniprotkb:Pygb(gene name)|psi-mi:Pygb(display_short)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Martins et al. (2018)	imex:IM-28469|pubmed:29476059	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26439741|imex:IM-28469-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSRNOG00000016271(gene)|ensembl:ENSRNOT00000023037(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001540"(amyloid-beta binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0010008"(endosome membrane)|go:"GO:0030660"(Golgi-associated vesicle membrane)|go:"GO:0031301"(integral component of organelle membrane)|go:"GO:0042985"(negative regulation of amyloid precursor protein biosynthetic process)|interpro:IPR007084(BRICHOS)|interpro:IPR040145|mint:Q5XIE8|refseq:NP_001006964.1|rgd:620727	interpro:IPR035090|rgd:3460|refseq:NP_037320.1|interpro:IPR011833(Glycogen/starch/alpha-glucan phosphorylase)|interpro:IPR000811(Glycosyl transferase, family 35)|mint:P53534|go:"GO:0005737"(cytoplasm)|go:"GO:0005977"(glycogen metabolic process)|go:"GO:0005980"(glycogen catabolic process)|go:"GO:0008184"(glycogen phosphorylase activity)|go:"GO:0030170"(pyridoxal phosphate binding)|go:"GO:0030246"(carbohydrate binding)|go:"GO:0030424"(axon)|go:"GO:0042802"(identical protein binding)|go:"GO:0102250"(linear malto-oligosaccharide phosphorylase activity)|go:"GO:0102499"(SHG alpha-glucan phosphorylase activity)|reactome:R-RNO-6798695	-	-	-	figure legend:st1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10116(rat-brain-cortex)|taxid:10116(Rattus norvegicus brain cortex)	-	2020/10/30	2020/10/30	rogid:DtE+ZXAZKdCMvUW5K+jXQ5bH07M10116	rogid:WcV4oiXMS78KKpVSzVnziBt5uD810116	rigid:3wclwrjZRvafcOruQOYnegkn54c	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q5XIE8	uniprotkb:P05065	intact:EBI-15348306|ensembl:ENSRNOP00000023037	intact:EBI-522118|uniprotkb:Q63038|ensembl:ENSRNOP00000068764|ensembl:ENSRNOP00000069507|ensembl:ENSRNOP00000069540	psi-mi:itm2b_rat(display_long)|uniprotkb:Itm2b(gene name)|psi-mi:Itm2b(display_short)|uniprotkb:Immature BRI2(gene name synonym)|uniprotkb:Transmembrane protein BRI(gene name synonym)	psi-mi:aldoa_rat(display_long)|uniprotkb:Muscle-type aldolase(gene name synonym)|uniprotkb:Aldoa(gene name)|psi-mi:Aldoa(display_short)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Martins et al. (2018)	imex:IM-28469|pubmed:29476059	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26439741|imex:IM-28469-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSRNOG00000016271(gene)|ensembl:ENSRNOT00000023037(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001540"(amyloid-beta binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0010008"(endosome membrane)|go:"GO:0030660"(Golgi-associated vesicle membrane)|go:"GO:0031301"(integral component of organelle membrane)|go:"GO:0042985"(negative regulation of amyloid precursor protein biosynthetic process)|interpro:IPR007084(BRICHOS)|interpro:IPR040145|mint:Q5XIE8|refseq:NP_001006964.1|rgd:620727	rgd:2089|refseq:NP_001170776.1|refseq:NP_036627.1|ensembl:ENSRNOG00000052802(gene)|ensembl:ENSRNOT00000080988(transcript)|ensembl:ENSRNOT00000087928(transcript)|ensembl:ENSRNOT00000088473(transcript)|go:"GO:0000792"(heterochromatin)|go:"GO:0001666"(response to hypoxia)|go:"GO:0002020"(protease binding)|go:"GO:0004332"(fructose-bisphosphate aldolase activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006096"(glycolytic process)|go:"GO:0009408"(response to heat)|go:"GO:0016020"(membrane)|go:"GO:0019242"(methylglyoxal biosynthetic process)|go:"GO:0030018"(Z disc)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0030388"(fructose 1,6-bisphosphate metabolic process)|go:"GO:0031430"(M band)|go:"GO:0032496"(response to lipopolysaccharide)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035094"(response to nicotine)|go:"GO:0035686"(sperm fibrous sheath)|go:"GO:0043627"(response to estrogen)|go:"GO:0051289"(protein homotetramerization)|interpro:IPR000741(Fructose-bisphosphate aldolase, class-I)|interpro:IPR013785(Aldolase-type TIM barrel)|interpro:IPR029768|mint:P05065|reactome:R-RNO-114608|reactome:R-RNO-6798695|reactome:R-RNO-70171|reactome:R-RNO-70263|refseq:XP_006230273.1|refseq:NP_001258465.1	-	-	-	figure legend:st1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10116(rat-brain-cortex)|taxid:10116(Rattus norvegicus brain cortex)	-	2020/10/30	2020/10/30	rogid:DtE+ZXAZKdCMvUW5K+jXQ5bH07M10116	rogid:dUcYtyffbl8dC/1SD/ZtEtiFyB010116	rigid:3wclwrjZRvafcOruQOYnegkn54c	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q5XIE8	uniprotkb:P62630	intact:EBI-15348306|ensembl:ENSRNOP00000023037	intact:EBI-917951|uniprotkb:P20001|uniprotkb:Q5BJW8|uniprotkb:Q64718|uniprotkb:Q78ED4|ensembl:ENSRNOP00000013608	psi-mi:itm2b_rat(display_long)|uniprotkb:Itm2b(gene name)|psi-mi:Itm2b(display_short)|uniprotkb:Immature BRI2(gene name synonym)|uniprotkb:Transmembrane protein BRI(gene name synonym)	psi-mi:ef1a1_rat(display_long)|uniprotkb:Eukaryotic elongation factor 1 A-1(gene name synonym)|uniprotkb:Elongation factor Tu(gene name synonym)|uniprotkb:Eef1a1(gene name)|psi-mi:Eef1a1(display_short)|uniprotkb:Eef1a(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Martins et al. (2018)	imex:IM-28469|pubmed:29476059	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26439741|imex:IM-28469-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSRNOG00000016271(gene)|ensembl:ENSRNOT00000023037(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001540"(amyloid-beta binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0010008"(endosome membrane)|go:"GO:0030660"(Golgi-associated vesicle membrane)|go:"GO:0031301"(integral component of organelle membrane)|go:"GO:0042985"(negative regulation of amyloid precursor protein biosynthetic process)|interpro:IPR007084(BRICHOS)|interpro:IPR040145|mint:Q5XIE8|refseq:NP_001006964.1|rgd:620727	rgd:67387|refseq:NP_787032.1|ensembl:ENSRNOG00000009439(gene)|ensembl:ENSRNOT00000013608(transcript)|go:"GO:0000049"(tRNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0003746"(translation elongation factor activity)|go:"GO:0003924"(GTPase activity)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005525"(GTP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006412"(translation)|go:"GO:0006414"(translational elongation)|go:"GO:0007568"(aging)|go:"GO:0010942"(positive regulation of cell death)|go:"GO:0010976"(positive regulation of neuron projection development)|go:"GO:0019900"(kinase binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030864"(cortical actin cytoskeleton)|go:"GO:0032587"(ruffle membrane)|go:"GO:0035690"|go:"GO:0042802"(identical protein binding)|go:"GO:0071364"(cellular response to epidermal growth factor stimulus)|go:"GO:1900022"(regulation of D-erythro-sphingosine kinase activity)|go:"GO:1903427"(negative regulation of reactive oxygen species biosynthetic process)|go:"GO:1990090"(cellular response to nerve growth factor stimulus)|interpro:IPR000795(Protein synthesis factor, GTP-binding)|interpro:IPR004160(Translation elongation factor EFTu/EF1A, C-terminal)|interpro:IPR004161(Translation elongation factor EFTu/EF1A, domain 2)|interpro:IPR004539(Translation elongation factor EF1A, eukaryotic and archaeal)|interpro:IPR009000(Translation elongation and initiation factors/Ribosomal, beta-barrel)|interpro:IPR009001(Translation elongation factor EF1A/initiation factor IF2gamma, C-terminal)|interpro:IPR027417|interpro:IPR031157|mint:P62630|reactome:R-RNO-156842|reactome:R-RNO-3371511|reactome:R-RNO-6798695|reactome:R-RNO-8876725	-	-	-	figure legend:st1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10116(rat-brain-cortex)|taxid:10116(Rattus norvegicus brain cortex)	-	2020/10/30	2020/10/30	rogid:DtE+ZXAZKdCMvUW5K+jXQ5bH07M10116	rogid:85G9Uje743KzA02bB/rmKuq2HbU10116	rigid:3wclwrjZRvafcOruQOYnegkn54c	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q5XIE8	uniprotkb:O35303	intact:EBI-15348306|ensembl:ENSRNOP00000023037	intact:EBI-1767447|uniprotkb:O35318|uniprotkb:O35319|uniprotkb:O35320|uniprotkb:O35321|uniprotkb:O35322|uniprotkb:O35323|uniprotkb:Q5U2W1|uniprotkb:Q792T7|uniprotkb:Q9R234|uniprotkb:Q9R277|ensembl:ENSRNOP00000002478	psi-mi:itm2b_rat(display_long)|uniprotkb:Itm2b(gene name)|psi-mi:Itm2b(display_short)|uniprotkb:Immature BRI2(gene name synonym)|uniprotkb:Transmembrane protein BRI(gene name synonym)	psi-mi:dnm1l_rat(display_long)|uniprotkb:Dnm1l(gene name)|psi-mi:Dnm1l(display_short)|uniprotkb:Dlp1(gene name synonym)|uniprotkb:Drp1(gene name synonym)|uniprotkb:Dynamin-like protein(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Martins et al. (2018)	imex:IM-28469|pubmed:29476059	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26439741|imex:IM-28469-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSRNOG00000016271(gene)|ensembl:ENSRNOT00000023037(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001540"(amyloid-beta binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0010008"(endosome membrane)|go:"GO:0030660"(Golgi-associated vesicle membrane)|go:"GO:0031301"(integral component of organelle membrane)|go:"GO:0042985"(negative regulation of amyloid precursor protein biosynthetic process)|interpro:IPR007084(BRICHOS)|interpro:IPR040145|mint:Q5XIE8|refseq:NP_001006964.1|rgd:620727	rgd:620416|refseq:NP_446107.2|refseq:XP_008767063.1|refseq:XP_008767064.1|refseq:XP_008767065.1|refseq:XP_006248785.1|dip:DIP-29699N|ensembl:ENSRNOG00000001813(gene)|ensembl:ENSRNOT00000002478(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0000266"(mitochondrial fission)|go:"GO:0001836"(release of cytochrome c from mitochondria)|go:"GO:0003374"(dynamin family protein polymerization involved in mitochondrial fission)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005777"(peroxisome)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0005874"(microtubule)|go:"GO:0005903"(brush border)|go:"GO:0006816"(calcium ion transport)|go:"GO:0007005"(mitochondrion organization)|go:"GO:0008017"(microtubule binding)|go:"GO:0008289"(lipid binding)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0010637"(negative regulation of mitochondrial fusion)|go:"GO:0010821"(regulation of mitochondrion organization)|go:"GO:0016020"(membrane)|go:"GO:0016559"(peroxisome fission)|go:"GO:0030276"(clathrin binding)|go:"GO:0030672"(synaptic vesicle membrane)|go:"GO:0030742"(GTP-dependent protein binding)|go:"GO:0031267"(small GTPase binding)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0036466"(synaptic vesicle recycling via endosome)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0043653"(mitochondrial fragmentation involved in apoptotic process)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0048312"(intracellular distribution of mitochondria)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0048488"(synaptic vesicle endocytosis)|go:"GO:0048511"(rhythmic process)|go:"GO:0050714"(positive regulation of protein secretion)|go:"GO:0051259"(protein complex oligomerization)|go:"GO:0051433"(BH2 domain binding)|go:"GO:0060047"(heart contraction)|go:"GO:0061003"(positive regulation of dendritic spine morphogenesis)|go:"GO:0061025"(membrane fusion)|go:"GO:0065003"(protein-containing complex assembly)|go:"GO:0070266"(necroptotic process)|go:"GO:0070584"(mitochondrion morphogenesis)|go:"GO:0070585"(protein localization to mitochondrion)|go:"GO:0071396"(cellular response to lipid)|go:"GO:0090023"(positive regulation of neutrophil chemotaxis)|go:"GO:0090141"(positive regulation of mitochondrial fission)|go:"GO:0090149"(mitochondrial membrane fission)|go:"GO:0090200"(positive regulation of release of cytochrome c from mitochondria)|go:"GO:0090650"(cellular response to oxygen-glucose deprivation)|go:"GO:0098835"(presynaptic endocytic zone membrane)|go:"GO:0099073"(mitochondrion-derived vesicle)|go:"GO:0099503"(secretory vesicle)|go:"GO:1900063"(regulation of peroxisome organization)|go:"GO:1900244"(positive regulation of synaptic vesicle endocytosis)|go:"GO:1903146"(regulation of autophagy of mitochondrion)|go:"GO:1903578"(regulation of ATP metabolic process)|go:"GO:1904579"(cellular response to thapsigargin)|go:"GO:1904666"(regulation of ubiquitin protein ligase activity)|go:"GO:1905395"(response to flavonoid)|go:"GO:1990910"(response to hypobaric hypoxia)|go:"GO:2000302"(positive regulation of synaptic vesicle exocytosis)|go:"GO:2001244"(positive regulation of intrinsic apoptotic signaling pathway)|interpro:IPR000375(Dynamin central region)|interpro:IPR003130(Dynamin GTPase effector)|interpro:IPR019762|interpro:IPR020850|interpro:IPR022812|interpro:IPR027417|interpro:IPR030381|interpro:IPR030556|mint:O35303|reactome:R-RNO-75153|interpro:IPR001401(Dynamin, GTPase region)	-	-	-	figure legend:st1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10116(rat-brain-cortex)|taxid:10116(Rattus norvegicus brain cortex)	-	2020/10/30	2020/10/30	rogid:DtE+ZXAZKdCMvUW5K+jXQ5bH07M10116	rogid:HkPGbvyZ4Tb3hJw1EqAya+FIcWg10116	rigid:3wclwrjZRvafcOruQOYnegkn54c	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q5XIE8	uniprotkb:P21575	intact:EBI-15348306|ensembl:ENSRNOP00000023037	intact:EBI-80070|ensembl:ENSRNOP00000041582	psi-mi:itm2b_rat(display_long)|uniprotkb:Itm2b(gene name)|psi-mi:Itm2b(display_short)|uniprotkb:Immature BRI2(gene name synonym)|uniprotkb:Transmembrane protein BRI(gene name synonym)	psi-mi:dyn1_rat(display_long)|uniprotkb:Dnm1(gene name)|psi-mi:Dnm1(display_short)|uniprotkb:Dnm(gene name synonym)|uniprotkb:D100(gene name synonym)|uniprotkb:Dynamin, brain(gene name synonym)|uniprotkb:B-dynamin(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Martins et al. (2018)	imex:IM-28469|pubmed:29476059	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26439741|imex:IM-28469-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSRNOG00000016271(gene)|ensembl:ENSRNOT00000023037(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001540"(amyloid-beta binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0010008"(endosome membrane)|go:"GO:0030660"(Golgi-associated vesicle membrane)|go:"GO:0031301"(integral component of organelle membrane)|go:"GO:0042985"(negative regulation of amyloid precursor protein biosynthetic process)|interpro:IPR007084(BRICHOS)|interpro:IPR040145|mint:Q5XIE8|refseq:NP_001006964.1|rgd:620727	rgd:71096|refseq:NP_542420.1|ensembl:ENSRNOG00000033835(gene)|ensembl:ENSRNOT00000047921(transcript)|go:"GO:0000266"(mitochondrial fission)|go:"GO:0001917"(photoreceptor inner segment)|go:"GO:0002031"(G protein-coupled receptor internalization)|go:"GO:0003374"(dynamin family protein polymerization involved in mitochondrial fission)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005874"(microtubule)|go:"GO:0005886"(plasma membrane)|go:"GO:0006897"(endocytosis)|go:"GO:0006898"(receptor-mediated endocytosis)|go:"GO:0007032"(endosome organization)|go:"GO:0008017"(microtubule binding)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0014069"(postsynaptic density)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0016020"(membrane)|go:"GO:0016185"(synaptic vesicle budding from presynaptic endocytic zone membrane)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030117"(membrane coat)|go:"GO:0030424"(axon)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0031623"(receptor internalization)|go:"GO:0031749"(D2 dopamine receptor binding)|go:"GO:0031966"(mitochondrial membrane)|go:"GO:0032991"(protein-containing complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0043196"(varicosity)|go:"GO:0044327"(dendritic spine head)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045202"(synapse)|go:"GO:0048488"(synaptic vesicle endocytosis)|go:"GO:0050803"(regulation of synapse structure or activity)|go:"GO:0050804"(modulation of chemical synaptic transmission)|go:"GO:0050998"(nitric-oxide synthase binding)|go:"GO:0061025"(membrane fusion)|go:"GO:0098684"(photoreceptor ribbon synapse)|go:"GO:0098835"(presynaptic endocytic zone membrane)|go:"GO:0098844"(postsynaptic endocytic zone membrane)|go:"GO:0098884"(postsynaptic neurotransmitter receptor internalization)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:1900242"(regulation of synaptic vesicle endocytosis)|go:"GO:1900244"(positive regulation of synaptic vesicle endocytosis)|go:"GO:1901998"(toxin transport)|go:"GO:1903423"(positive regulation of synaptic vesicle recycling)|go:"GO:1904645"(response to amyloid-beta)|interpro:IPR000375(Dynamin central region)|interpro:IPR001401(Dynamin, GTPase region)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR003130(Dynamin GTPase effector)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR019762|interpro:IPR020850|interpro:IPR022812|interpro:IPR027417|interpro:IPR027741|interpro:IPR030381|mint:P21575|rcsb pdb:2AKA|rcsb pdb:3ZVR|reactome:R-RNO-190873|reactome:R-RNO-196025|reactome:R-RNO-2132295|reactome:R-RNO-437239|reactome:R-RNO-8856828|dip:DIP-30978N	-	-	-	figure legend:st1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10116(rat-brain-cortex)|taxid:10116(Rattus norvegicus brain cortex)	-	2020/10/30	2020/10/30	rogid:DtE+ZXAZKdCMvUW5K+jXQ5bH07M10116	rogid:x9J/VoMgoDFBHadzOhnN3yhTjfs10116	rigid:3wclwrjZRvafcOruQOYnegkn54c	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q5XIE8	uniprotkb:Q6AYH5	intact:EBI-15348306|ensembl:ENSRNOP00000023037	intact:EBI-920539|ensembl:ENSRNOP00000008120	psi-mi:itm2b_rat(display_long)|uniprotkb:Itm2b(gene name)|psi-mi:Itm2b(display_short)|uniprotkb:Immature BRI2(gene name synonym)|uniprotkb:Transmembrane protein BRI(gene name synonym)	psi-mi:dctn2_rat(display_long)|uniprotkb:Dctn2(gene name)|psi-mi:Dctn2(display_short)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Martins et al. (2018)	imex:IM-28469|pubmed:29476059	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26439741|imex:IM-28469-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSRNOG00000016271(gene)|ensembl:ENSRNOT00000023037(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001540"(amyloid-beta binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0010008"(endosome membrane)|go:"GO:0030660"(Golgi-associated vesicle membrane)|go:"GO:0031301"(integral component of organelle membrane)|go:"GO:0042985"(negative regulation of amyloid precursor protein biosynthetic process)|interpro:IPR007084(BRICHOS)|interpro:IPR040145|mint:Q5XIE8|refseq:NP_001006964.1|rgd:620727	rgd:1303182|refseq:NP_001004239.1|ensembl:ENSRNOG00000025481(gene)|ensembl:ENSRNOT00000008120(transcript)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0000776"(kinetochore)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005869"(dynactin complex)|go:"GO:0005874"(microtubule)|go:"GO:0007052"(mitotic spindle organization)|go:"GO:0007080"(mitotic metaphase plate congression)|go:"GO:0016020"(membrane)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030286"(dynein complex)|go:"GO:0030426"(growth cone)|go:"GO:0030507"(spectrin binding)|go:"GO:0031982"(vesicle)|go:"GO:0032402"(melanosome transport)|go:"GO:0042802"(identical protein binding)|go:"GO:0071539"(protein localization to centrosome)|interpro:IPR028133|mint:Q6AYH5|reactome:R-RNO-2132295|reactome:R-RNO-2565942|reactome:R-RNO-3371497|reactome:R-RNO-380259|reactome:R-RNO-380270|reactome:R-RNO-380284|reactome:R-RNO-380320|reactome:R-RNO-5620912|reactome:R-RNO-6807878|reactome:R-RNO-6811436|reactome:R-RNO-8854518	-	-	-	figure legend:st1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10116(rat-brain-cortex)|taxid:10116(Rattus norvegicus brain cortex)	-	2020/10/30	2020/10/30	rogid:DtE+ZXAZKdCMvUW5K+jXQ5bH07M10116	rogid:B7LyMXi8DNGgOm+GDSigf2eHuE810116	rigid:3wclwrjZRvafcOruQOYnegkn54c	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q5XIE8	uniprotkb:Q07266	intact:EBI-15348306|ensembl:ENSRNOP00000023037	intact:EBI-918187|uniprotkb:A5D6R1|uniprotkb:O70205	psi-mi:itm2b_rat(display_long)|uniprotkb:Itm2b(gene name)|psi-mi:Itm2b(display_short)|uniprotkb:Immature BRI2(gene name synonym)|uniprotkb:Transmembrane protein BRI(gene name synonym)	psi-mi:dreb_rat(display_long)|uniprotkb:Dbn1(gene name)|psi-mi:Dbn1(display_short)|uniprotkb:Developmentally-regulated brain protein(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Martins et al. (2018)	imex:IM-28469|pubmed:29476059	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26439741|imex:IM-28469-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSRNOG00000016271(gene)|ensembl:ENSRNOT00000023037(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001540"(amyloid-beta binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0010008"(endosome membrane)|go:"GO:0030660"(Golgi-associated vesicle membrane)|go:"GO:0031301"(integral component of organelle membrane)|go:"GO:0042985"(negative regulation of amyloid precursor protein biosynthetic process)|interpro:IPR007084(BRICHOS)|interpro:IPR040145|mint:Q5XIE8|refseq:NP_001006964.1|rgd:620727	rgd:70885|refseq:NP_112286.1|interpro:IPR002108(Actin-binding, cofilin/tropomyosin type)|interpro:IPR028438|mint:Q07266|interpro:IPR029006|refseq:XP_006253719.1|go:"GO:0001701"(in utero embryonic development)|go:"GO:0005522"(profilin binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005921"(gap junction)|go:"GO:0007015"(actin filament organization)|go:"GO:0007283"(spermatogenesis)|go:"GO:0007399"(nervous system development)|go:"GO:0007420"(brain development)|go:"GO:0007568"(aging)|go:"GO:0008092"(cytoskeletal protein binding)|go:"GO:0010643"(cell communication by chemical coupling)|go:"GO:0010644"(cell communication by electrical coupling)|go:"GO:0010811"(positive regulation of cell-substrate adhesion)|go:"GO:0010976"(positive regulation of neuron projection development)|go:"GO:0014069"(postsynaptic density)|go:"GO:0014823"(response to activity)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0016020"(membrane)|go:"GO:0030027"(lamellipodium)|go:"GO:0030175"(filopodium)|go:"GO:0030425"(dendrite)|go:"GO:0030426"(growth cone)|go:"GO:0030427"(site of polarized growth)|go:"GO:0030833"(regulation of actin filament polymerization)|go:"GO:0030864"(cortical actin cytoskeleton)|go:"GO:0031915"(positive regulation of synaptic plasticity)|go:"GO:0032232"(negative regulation of actin filament bundle assembly)|go:"GO:0032279"(asymmetric synapse)|go:"GO:0032507"(maintenance of protein location in cell)|go:"GO:0042493"|go:"GO:0043025"(neuronal cell body)|go:"GO:0043197"(dendritic spine)|go:"GO:0043198"(dendritic shaft)|go:"GO:0044295"(axonal growth cone)|go:"GO:0044308"(axonal spine)|go:"GO:0044309"(neuron spine)|go:"GO:0045211"(postsynaptic membrane)|go:"GO:0045773"(positive regulation of axon extension)|go:"GO:0048286"(lung alveolus development)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0048699"(generation of neurons)|go:"GO:0048812"(neuron projection morphogenesis)|go:"GO:0051015"(actin filament binding)|go:"GO:0051220"(cytoplasmic sequestering of protein)|go:"GO:0051489"(regulation of filopodium assembly)|go:"GO:0060076"(excitatory synapse)|go:"GO:0060134"(prepulse inhibition)|go:"GO:0061003"(positive regulation of dendritic spine morphogenesis)|go:"GO:0061351"(neural precursor cell proliferation)|go:"GO:0071356"(cellular response to tumor necrosis factor)|go:"GO:0071481"(cellular response to X-ray)|go:"GO:0071560"(cellular response to transforming growth factor beta stimulus)|go:"GO:0090327"(negative regulation of locomotion involved in locomotory behavior)|go:"GO:0098828"(modulation of inhibitory postsynaptic potential)|go:"GO:0098871"(postsynaptic actin cytoskeleton)|go:"GO:0098974"(postsynaptic actin cytoskeleton organization)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099524"(postsynaptic cytosol)|go:"GO:0120080"(obsolete negative regulation of microfilament motor activity)|go:"GO:1900026"(positive regulation of substrate adhesion-dependent cell spreading)|go:"GO:1902685"(positive regulation of receptor localization to synapse)|go:"GO:1902737"(dendritic filopodium)|go:"GO:1902897"(regulation of postsynaptic density protein 95 clustering)|go:"GO:1904113"(negative regulation of muscle filament sliding)|go:"GO:2000463"(positive regulation of excitatory postsynaptic potential)|reactome:R-RNO-9013405|reactome:R-RNO-9013407|reactome:R-RNO-9013418|reactome:R-RNO-9013422	-	-	-	figure legend:st1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10116(rat-brain-cortex)|taxid:10116(Rattus norvegicus brain cortex)	-	2020/10/30	2020/10/30	rogid:DtE+ZXAZKdCMvUW5K+jXQ5bH07M10116	rogid:ywce7jMZtfDwzFWvAURT5bUsmdY10116	rigid:3wclwrjZRvafcOruQOYnegkn54c	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q5XIE8	uniprotkb:P47942	intact:EBI-15348306|ensembl:ENSRNOP00000023037	intact:EBI-917570|intact:EBI-6096016|ensembl:ENSRNOP00000012996	psi-mi:itm2b_rat(display_long)|uniprotkb:Itm2b(gene name)|psi-mi:Itm2b(display_short)|uniprotkb:Immature BRI2(gene name synonym)|uniprotkb:Transmembrane protein BRI(gene name synonym)	psi-mi:dpyl2_rat(display_long)|uniprotkb:Turned on after division 64 kDa protein(gene name synonym)|uniprotkb:Collapsin response mediator protein 2(gene name synonym)|uniprotkb:Dpysl2(gene name)|psi-mi:Dpysl2(display_short)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Martins et al. (2018)	imex:IM-28469|pubmed:29476059	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26439741|imex:IM-28469-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSRNOG00000016271(gene)|ensembl:ENSRNOT00000023037(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001540"(amyloid-beta binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0010008"(endosome membrane)|go:"GO:0030660"(Golgi-associated vesicle membrane)|go:"GO:0031301"(integral component of organelle membrane)|go:"GO:0042985"(negative regulation of amyloid precursor protein biosynthetic process)|interpro:IPR007084(BRICHOS)|interpro:IPR040145|mint:Q5XIE8|refseq:NP_001006964.1|rgd:620727	rgd:2517|refseq:NP_001099187.1|ensembl:ENSRNOG00000009625(gene)|ensembl:ENSRNOT00000012996(transcript)|go:"GO:0001975"(response to amphetamine)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005886"(plasma membrane)|go:"GO:0006897"(endocytosis)|go:"GO:0007010"(cytoskeleton organization)|go:"GO:0007411"(axon guidance)|go:"GO:0007420"(brain development)|go:"GO:0008017"(microtubule binding)|go:"GO:0010975"(regulation of neuron projection development)|go:"GO:0014049"(positive regulation of glutamate secretion)|go:"GO:0016810"("hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds")|go:"GO:0019901"(protein kinase binding)|go:"GO:0021510"(spinal cord development)|go:"GO:0021772"(olfactory bulb development)|go:"GO:0030424"(axon)|go:"GO:0030425"(dendrite)|go:"GO:0030426"(growth cone)|go:"GO:0030516"(regulation of axon extension)|go:"GO:0032991"(protein-containing complex)|go:"GO:0042220"(response to cocaine)|go:"GO:0042493"|go:"GO:0042802"(identical protein binding)|go:"GO:0043005"(neuron projection)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043209"(myelin sheath)|go:"GO:0045664"(regulation of neuron differentiation)|go:"GO:0048489"(synaptic vesicle transport)|go:"GO:0098793"(presynapse)|interpro:IPR006680(Amidohydrolase 1)|interpro:IPR011059(Metal-dependent hydrolase, composite)|interpro:IPR011778(D-hydantoinase)|interpro:IPR030615|interpro:IPR032466|mint:P47942|reactome:R-RNO-399956|reactome:R-RNO-437239	-	-	-	figure legend:st1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10116(rat-brain-cortex)|taxid:10116(Rattus norvegicus brain cortex)	-	2020/10/30	2020/10/30	rogid:DtE+ZXAZKdCMvUW5K+jXQ5bH07M10116	rogid:97yc8TNEPMcGtGNRLvl+KV+DYr010116	rigid:3wclwrjZRvafcOruQOYnegkn54c	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q5XIE8	uniprotkb:P38650	intact:EBI-15348306|ensembl:ENSRNOP00000023037	intact:EBI-349489|uniprotkb:Q63178	psi-mi:itm2b_rat(display_long)|uniprotkb:Itm2b(gene name)|psi-mi:Itm2b(display_short)|uniprotkb:Immature BRI2(gene name synonym)|uniprotkb:Transmembrane protein BRI(gene name synonym)	psi-mi:dyhc1_rat(display_long)|uniprotkb:Dync1h1(gene name)|psi-mi:Dync1h1(display_short)|uniprotkb:Dnch1(gene name synonym)|uniprotkb:Dnec1(gene name synonym)|uniprotkb:Map1c(gene name synonym)|uniprotkb:Dhc1(gene name synonym)|uniprotkb:Dyhc(gene name synonym)|uniprotkb:Cytoplasmic dynein heavy chain 1(gene name synonym)|uniprotkb:Dynein heavy chain, cytosolic(gene name synonym)|uniprotkb:MAP 1C(gene name synonym)|uniprotkb:Dnchc1(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Martins et al. (2018)	imex:IM-28469|pubmed:29476059	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26439741|imex:IM-28469-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSRNOG00000016271(gene)|ensembl:ENSRNOT00000023037(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001540"(amyloid-beta binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0010008"(endosome membrane)|go:"GO:0030660"(Golgi-associated vesicle membrane)|go:"GO:0031301"(integral component of organelle membrane)|go:"GO:0042985"(negative regulation of amyloid precursor protein biosynthetic process)|interpro:IPR007084(BRICHOS)|interpro:IPR040145|mint:Q5XIE8|refseq:NP_001006964.1|rgd:620727	rgd:2511|refseq:NP_062099.3|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR004273(Dynein heavy chain)|interpro:IPR024317|interpro:IPR013594(Dynein heavy chain, N-terminal region 1)|interpro:IPR013602(Dynein heavy chain, N-terminal region 2)|interpro:IPR024743|go:"GO:0005737"(cytoplasm)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0002177"(manchette)|go:"GO:0005524"(ATP binding)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005813"(centrosome)|go:"GO:0005868"(cytoplasmic dynein complex)|go:"GO:0005874"(microtubule)|go:"GO:0005881"(cytoplasmic microtubule)|go:"GO:0005938"(cell cortex)|go:"GO:0007018"(microtubule-based movement)|go:"GO:0007097"(nuclear migration)|go:"GO:0007286"(spermatid development)|go:"GO:0008090"(retrograde axonal transport)|go:"GO:0008569"(minus-end-directed microtubule motor activity)|go:"GO:0030175"(filopodium)|go:"GO:0030286"(dynein complex)|go:"GO:0030424"(axon)|go:"GO:0031122"(cytoplasmic microtubule organization)|go:"GO:0032388"(positive regulation of intracellular transport)|go:"GO:0034063"(stress granule assembly)|go:"GO:0043025"(neuronal cell body)|go:"GO:0033962"(P-body assembly)|go:"GO:0045505"(dynein intermediate chain binding)|go:"GO:0051293"(establishment of spindle localization)|go:"GO:0051301"(cell division)|go:"GO:0051959"(dynein light intermediate chain binding)|go:"GO:0060236"(regulation of mitotic spindle organization)|go:"GO:0072382"(minus-end-directed vesicle transport along microtubule)|go:"GO:0090235"(regulation of metaphase plate congression)|go:"GO:0120162"(positive regulation of cold-induced thermogenesis)|go:"GO:1904115"(axon cytoplasm)|go:"GO:1905243"(cellular response to 3,3',5-triiodo-L-thyronine)|go:"GO:1905832"(positive regulation of spindle assembly)|go:"GO:1990090"(cellular response to nerve growth factor stimulus)|reactome:R-RNO-141444|reactome:R-RNO-2132295|reactome:R-RNO-2467813|reactome:R-RNO-2500257|reactome:R-RNO-2565942|reactome:R-RNO-3371497|reactome:R-RNO-380259|reactome:R-RNO-380270|reactome:R-RNO-380284|reactome:R-RNO-380320|reactome:R-RNO-5620912|reactome:R-RNO-5663220|reactome:R-RNO-6798695|reactome:R-RNO-6807878|reactome:R-RNO-6811436|reactome:R-RNO-68877|reactome:R-RNO-8854518|reactome:R-RNO-9646399|reactome:R-RNO-9648025|interpro:IPR042219|interpro:IPR042222|interpro:IPR042228|interpro:IPR027417|mint:P38650|interpro:IPR035699|interpro:IPR035706|interpro:IPR041228|interpro:IPR041466|interpro:IPR041658|interpro:IPR043157|interpro:IPR043160	-	-	-	figure legend:st1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10116(rat-brain-cortex)|taxid:10116(Rattus norvegicus brain cortex)	-	2020/10/30	2020/10/30	rogid:DtE+ZXAZKdCMvUW5K+jXQ5bH07M10116	rogid:RxE6eIUsLysOcDObdE+E7cBOC5w10116	rigid:3wclwrjZRvafcOruQOYnegkn54c	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q5XIE8	uniprotkb:Q63198	intact:EBI-15348306|ensembl:ENSRNOP00000023037	intact:EBI-2255922|ensembl:ENSRNOP00000006219|ensembl:ENSRNOP00000071355	psi-mi:itm2b_rat(display_long)|uniprotkb:Itm2b(gene name)|psi-mi:Itm2b(display_short)|uniprotkb:Immature BRI2(gene name synonym)|uniprotkb:Transmembrane protein BRI(gene name synonym)	psi-mi:cntn1_rat(display_long)|uniprotkb:Cntn1(gene name)|psi-mi:Cntn1(display_short)|uniprotkb:Neural cell surface protein F3(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Martins et al. (2018)	imex:IM-28469|pubmed:29476059	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26439741|imex:IM-28469-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSRNOG00000016271(gene)|ensembl:ENSRNOT00000023037(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001540"(amyloid-beta binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0010008"(endosome membrane)|go:"GO:0030660"(Golgi-associated vesicle membrane)|go:"GO:0031301"(integral component of organelle membrane)|go:"GO:0042985"(negative regulation of amyloid precursor protein biosynthetic process)|interpro:IPR007084(BRICHOS)|interpro:IPR040145|mint:Q5XIE8|refseq:NP_001006964.1|rgd:620727	refseq:XP_017450105.1|rgd:621300|refseq:NP_476459.1|refseq:XP_006242239.1|dip:DIP-53082N|ensembl:ENSRNOG00000004438(gene)|ensembl:ENSRNOT00000006219(transcript)|ensembl:ENSRNOT00000080621(transcript)|go:"GO:0005886"(plasma membrane)|go:"GO:0007155"(cell adhesion)|go:"GO:0007219"(Notch signaling pathway)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010765"(positive regulation of sodium ion transport)|go:"GO:0010976"(positive regulation of neuron projection development)|go:"GO:0021549"(cerebellum development)|go:"GO:0030246"(carbohydrate binding)|go:"GO:0031175"(neuron projection development)|go:"GO:0045121"(membrane raft)|go:"GO:0050731"(positive regulation of peptidyl-tyrosine phosphorylation)|go:"GO:0099025"(anchored component of postsynaptic membrane)|go:"GO:0099026"(anchored component of presynaptic membrane)|interpro:IPR003598(Immunoglobulin subtype 2)|interpro:IPR003599(Immunoglobulin subtype)|interpro:IPR003961(Fibronectin, type III)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR013098(Immunoglobulin I-set)|interpro:IPR013151(Immunoglobulin)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR036116|interpro:IPR036179|interpro:IPR036992|mint:Q63198	-	-	-	figure legend:st1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10116(rat-brain-cortex)|taxid:10116(Rattus norvegicus brain cortex)	-	2020/10/30	2020/10/30	rogid:DtE+ZXAZKdCMvUW5K+jXQ5bH07M10116	rogid:xwArPbuIT63LL9S/vyET64hKfUk10116	rigid:3wclwrjZRvafcOruQOYnegkn54c	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q5XIE8	uniprotkb:P08082	intact:EBI-15348306|ensembl:ENSRNOP00000023037	intact:EBI-10055575|ensembl:ENSRNOP00000023651	psi-mi:itm2b_rat(display_long)|uniprotkb:Itm2b(gene name)|psi-mi:Itm2b(display_short)|uniprotkb:Immature BRI2(gene name synonym)|uniprotkb:Transmembrane protein BRI(gene name synonym)	psi-mi:clcb_rat(display_long)|uniprotkb:Cltb(gene name)|psi-mi:Cltb(display_short)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Martins et al. (2018)	imex:IM-28469|pubmed:29476059	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26439741|imex:IM-28469-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSRNOG00000016271(gene)|ensembl:ENSRNOT00000023037(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001540"(amyloid-beta binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0010008"(endosome membrane)|go:"GO:0030660"(Golgi-associated vesicle membrane)|go:"GO:0031301"(integral component of organelle membrane)|go:"GO:0042985"(negative regulation of amyloid precursor protein biosynthetic process)|interpro:IPR007084(BRICHOS)|interpro:IPR040145|mint:Q5XIE8|refseq:NP_001006964.1|rgd:620727	rgd:621353|refseq:NP_446287.1|refseq:XP_006253657.1|ensembl:ENSRNOG00000017506(gene)|ensembl:ENSRNOT00000023651(transcript)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005326"(neurotransmitter transmembrane transporter activity)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006836"(neurotransmitter transport)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0007269"(neurotransmitter secretion)|go:"GO:0016183"(synaptic vesicle coating)|go:"GO:0030118"(clathrin coat)|go:"GO:0030125"(clathrin vesicle coat)|go:"GO:0030130"(clathrin coat of trans-Golgi network vesicle)|go:"GO:0030132"(clathrin coat of coated pit)|go:"GO:0030672"(synaptic vesicle membrane)|go:"GO:0032050"(clathrin heavy chain binding)|go:"GO:0042277"(peptide binding)|go:"GO:0048268"(clathrin coat assembly)|go:"GO:0060170"(ciliary membrane)|go:"GO:0072583"(clathrin-dependent endocytosis)|go:"GO:0098835"(presynaptic endocytic zone membrane)|go:"GO:0099631"(postsynaptic endocytic zone cytoplasmic component)|interpro:IPR000996(Clathrin light chain)|mint:P08082|reactome:R-RNO-190873|reactome:R-RNO-196025|reactome:R-RNO-432720|reactome:R-RNO-5099900|reactome:R-RNO-5140745|reactome:R-RNO-8856825|reactome:R-RNO-8856828	-	-	-	figure legend:st1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10116(rat-brain-cortex)|taxid:10116(Rattus norvegicus brain cortex)	-	2020/10/30	2020/10/30	rogid:DtE+ZXAZKdCMvUW5K+jXQ5bH07M10116	rogid:0DE/O9BdSzs0dUd4wVWHN8uVaGU10116	rigid:3wclwrjZRvafcOruQOYnegkn54c	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q5XIE8	uniprotkb:P08081	intact:EBI-15348306|ensembl:ENSRNOP00000023037	intact:EBI-916140|ensembl:ENSRNOP00000019737	psi-mi:itm2b_rat(display_long)|uniprotkb:Itm2b(gene name)|psi-mi:Itm2b(display_short)|uniprotkb:Immature BRI2(gene name synonym)|uniprotkb:Transmembrane protein BRI(gene name synonym)	psi-mi:clca_rat(display_long)|uniprotkb:Clta(gene name)|psi-mi:Clta(display_short)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Martins et al. (2018)	imex:IM-28469|pubmed:29476059	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26439741|imex:IM-28469-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSRNOG00000016271(gene)|ensembl:ENSRNOT00000023037(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001540"(amyloid-beta binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0010008"(endosome membrane)|go:"GO:0030660"(Golgi-associated vesicle membrane)|go:"GO:0031301"(integral component of organelle membrane)|go:"GO:0042985"(negative regulation of amyloid precursor protein biosynthetic process)|interpro:IPR007084(BRICHOS)|interpro:IPR040145|mint:Q5XIE8|refseq:NP_001006964.1|rgd:620727	ensembl:ENSRNOG00000014635(gene)|ensembl:ENSRNOT00000019737(transcript)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005819"(spindle)|go:"GO:0005886"(plasma membrane)|go:"GO:0005905"(clathrin-coated pit)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006897"(endocytosis)|go:"GO:0007049"(cell cycle)|go:"GO:0030118"(clathrin coat)|go:"GO:0030125"(clathrin vesicle coat)|go:"GO:0030130"(clathrin coat of trans-Golgi network vesicle)|go:"GO:0030132"(clathrin coat of coated pit)|go:"GO:0030136"(clathrin-coated vesicle)|go:"GO:0030669"(clathrin-coated endocytic vesicle membrane)|go:"GO:0030672"(synaptic vesicle membrane)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0032050"(clathrin heavy chain binding)|go:"GO:0042277"(peptide binding)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0048268"(clathrin coat assembly)|go:"GO:0051020"(GTPase binding)|go:"GO:0051301"(cell division)|go:"GO:0071439"(clathrin complex)|go:"GO:0072583"(clathrin-dependent endocytosis)|go:"GO:0098835"(presynaptic endocytic zone membrane)|go:"GO:0098843"(postsynaptic endocytic zone)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099631"(postsynaptic endocytic zone cytoplasmic component)|interpro:IPR000996(Clathrin light chain)|mint:P08081|reactome:R-RNO-177504|reactome:R-RNO-190873|reactome:R-RNO-196025|reactome:R-RNO-2132295|reactome:R-RNO-432720|reactome:R-RNO-432722|reactome:R-RNO-437239|reactome:R-RNO-5099900|reactome:R-RNO-5140745|reactome:R-RNO-8856825|reactome:R-RNO-8856828|reactome:R-RNO-8866427|reactome:R-RNO-8964038|rgd:70919|refseq:NP_114180.1|refseq:XP_006238166.1|refseq:XP_006238168.1|dip:DIP-36947N	-	-	-	figure legend:st1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10116(rat-brain-cortex)|taxid:10116(Rattus norvegicus brain cortex)	-	2020/10/30	2020/10/30	rogid:DtE+ZXAZKdCMvUW5K+jXQ5bH07M10116	rogid:josnOtPnIhM+WCMg+3/jsbSvdec10116	rigid:3wclwrjZRvafcOruQOYnegkn54c	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q5XIE8	uniprotkb:P11442	intact:EBI-15348306|ensembl:ENSRNOP00000023037	intact:EBI-397997	psi-mi:itm2b_rat(display_long)|uniprotkb:Itm2b(gene name)|psi-mi:Itm2b(display_short)|uniprotkb:Immature BRI2(gene name synonym)|uniprotkb:Transmembrane protein BRI(gene name synonym)	psi-mi:clh1_rat(display_long)|uniprotkb:Cltc(gene name)|psi-mi:Cltc(display_short)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Martins et al. (2018)	imex:IM-28469|pubmed:29476059	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26439741|imex:IM-28469-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSRNOG00000016271(gene)|ensembl:ENSRNOT00000023037(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001540"(amyloid-beta binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0010008"(endosome membrane)|go:"GO:0030660"(Golgi-associated vesicle membrane)|go:"GO:0031301"(integral component of organelle membrane)|go:"GO:0042985"(negative regulation of amyloid precursor protein biosynthetic process)|interpro:IPR007084(BRICHOS)|interpro:IPR040145|mint:Q5XIE8|refseq:NP_001006964.1|rgd:620727	rgd:2364|refseq:NP_062172.1|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0003725"(double-stranded RNA binding)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005819"(spindle)|go:"GO:0005829"(cytosol)|go:"GO:0005905"(clathrin-coated pit)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006898"(receptor-mediated endocytosis)|go:"GO:0006914"(autophagy)|go:"GO:0007030"(Golgi organization)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0016020"(membrane)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030117"(membrane coat)|go:"GO:0030118"(clathrin coat)|go:"GO:0030130"(clathrin coat of trans-Golgi network vesicle)|go:"GO:0030132"(clathrin coat of coated pit)|go:"GO:0030136"(clathrin-coated vesicle)|go:"GO:0030315"(T-tubule)|go:"GO:0030506"(ankyrin binding)|go:"GO:0030669"(clathrin-coated endocytic vesicle membrane)|go:"GO:0031072"(heat shock protein binding)|go:"GO:0031623"(receptor internalization)|go:"GO:0032051"(clathrin light chain binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033572"(transferrin transport)|go:"GO:0042147"(retrograde transport, endosome to Golgi)|go:"GO:0042277"(peptide binding)|go:"GO:0042383"(sarcolemma)|go:"GO:0042470"(melanosome)|go:"GO:0043195"(terminal bouton)|go:"GO:0045334"(clathrin-coated endocytic vesicle)|interpro:IPR015348(Clathrin, heavy chain, linker, core motif)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR016025(Clathrin, heavy chain, linker and propeller)|go:"GO:0048268"(clathrin coat assembly)|go:"GO:0048488"(synaptic vesicle endocytosis)|go:"GO:0050750"(low-density lipoprotein particle receptor binding)|go:"GO:0060236"(regulation of mitotic spindle organization)|go:"GO:0071439"(clathrin complex)|go:"GO:0072583"(clathrin-dependent endocytosis)|go:"GO:0097718"(disordered domain specific binding)|go:"GO:0098684"(photoreceptor ribbon synapse)|go:"GO:0098835"(presynaptic endocytic zone membrane)|go:"GO:0098850"(extrinsic component of synaptic vesicle membrane)|go:"GO:0150093"(amyloid-beta clearance by transcytosis)|go:"GO:1900126"(negative regulation of hyaluronan biosynthetic process)|go:"GO:1903077"(negative regulation of protein localization to plasma membrane)|go:"GO:1990381"(ubiquitin-specific protease binding)|go:"GO:1990498"(mitotic spindle microtubule)|interpro:IPR000547(Clathrin, heavy chain/VPS, 7-fold repeat)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR016341(Clathrin, heavy chain)|interpro:IPR022365|rcsb pdb:1BPO|rcsb pdb:1C9I|rcsb pdb:1C9L|reactome:R-RNO-177504|reactome:R-RNO-190873|reactome:R-RNO-196025|reactome:R-RNO-2132295|reactome:R-RNO-432720|reactome:R-RNO-432722|reactome:R-RNO-437239|reactome:R-RNO-5099900|reactome:R-RNO-5140745|reactome:R-RNO-8856825|reactome:R-RNO-8856828|reactome:R-RNO-8866427|reactome:R-RNO-8964038|reactome:R-RNO-9013420|reactome:R-RNO-9013424|mint:P11442|dip:DIP-36966N	-	-	-	figure legend:st1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10116(rat-brain-cortex)|taxid:10116(Rattus norvegicus brain cortex)	-	2020/10/30	2020/10/30	rogid:DtE+ZXAZKdCMvUW5K+jXQ5bH07M10116	rogid:IRKdzbAIpw7D7qHqyxStNyfI38g10116	rigid:3wclwrjZRvafcOruQOYnegkn54c	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q5XIE8	uniprotkb:Q05140	intact:EBI-15348306|ensembl:ENSRNOP00000023037	intact:EBI-1374805	psi-mi:itm2b_rat(display_long)|uniprotkb:Itm2b(gene name)|psi-mi:Itm2b(display_short)|uniprotkb:Immature BRI2(gene name synonym)|uniprotkb:Transmembrane protein BRI(gene name synonym)	psi-mi:ap180_rat(display_long)|uniprotkb:Snap91(gene name)|psi-mi:Snap91(display_short)|uniprotkb:Clathrin coat-associated protein AP180(gene name synonym)|uniprotkb:91 kDa synaptosomal-associated protein(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Martins et al. (2018)	imex:IM-28469|pubmed:29476059	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26439741|imex:IM-28469-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSRNOG00000016271(gene)|ensembl:ENSRNOT00000023037(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001540"(amyloid-beta binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0010008"(endosome membrane)|go:"GO:0030660"(Golgi-associated vesicle membrane)|go:"GO:0031301"(integral component of organelle membrane)|go:"GO:0042985"(negative regulation of amyloid precursor protein biosynthetic process)|interpro:IPR007084(BRICHOS)|interpro:IPR040145|mint:Q5XIE8|refseq:NP_001006964.1|rgd:620727	rgd:69276|refseq:NP_113916.1|interpro:IPR011417(ANTH)|interpro:IPR014712(Clathrin adaptor, phosphoinositide-binding, GAT-like)|interpro:IPR008942(ENTH/VHS)|interpro:IPR013809(Epsin-like, N-terminal)|mint:Q05140|go:"GO:0072583"(clathrin-dependent endocytosis)|go:"GO:0098685"(Schaffer collateral - CA1 synapse)|go:"GO:0098688"(parallel fiber to Purkinje cell synapse)|go:"GO:0098830"(presynaptic endosome)|go:"GO:0098833"(presynaptic endocytic zone)|go:"GO:0098894"(extrinsic component of presynaptic endocytic zone membrane)|go:"GO:1900242"(regulation of synaptic vesicle endocytosis)|go:"GO:1900244"(positive regulation of synaptic vesicle endocytosis)|go:"GO:1900275"(negative regulation of phospholipase C activity)|go:"GO:1904006"(negative regulation of phospholipase D activity)|go:"GO:1905445"(positive regulation of clathrin coat assembly)|go:"GO:2000331"(regulation of terminal button organization)|go:"GO:2000369"(regulation of clathrin-dependent endocytosis)|go:"GO:2000809"(positive regulation of synaptic vesicle clustering)|reactome:R-RNO-8856825|reactome:R-RNO-8856828|go:"GO:0000149"(SNARE binding)|go:"GO:0000822"(inositol hexakisphosphate binding)|go:"GO:0005545"(1-phosphatidylinositol binding)|go:"GO:0005546"(phosphatidylinositol-4,5-bisphosphate binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005905"(clathrin-coated pit)|go:"GO:0006900"(vesicle budding from membrane)|go:"GO:0007163"(establishment or maintenance of cell polarity)|go:"GO:0007268"(chemical synaptic transmission)|go:"GO:0007269"(neurotransmitter secretion)|go:"GO:0007409"(axonogenesis)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0014069"(postsynaptic density)|go:"GO:0015031"(protein transport)|go:"GO:0016185"(synaptic vesicle budding from presynaptic endocytic zone membrane)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030100"(regulation of endocytosis)|go:"GO:0030136"(clathrin-coated vesicle)|go:"GO:0031313"(extrinsic component of endosome membrane)|go:"GO:0032050"(clathrin heavy chain binding)|go:"GO:0035615"(clathrin adaptor activity)|go:"GO:0042169"(SH2 domain binding)|go:"GO:0042734"(presynaptic membrane)|go:"GO:0043005"(neuron projection)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043195"(terminal bouton)|go:"GO:0043274"(phospholipase binding)|go:"GO:0043679"(axon terminus)|go:"GO:0045211"(postsynaptic membrane)|go:"GO:0048268"(clathrin coat assembly)|go:"GO:0048488"(synaptic vesicle endocytosis)|go:"GO:0048666"(neuron development)|go:"GO:0048787"(presynaptic active zone membrane)|go:"GO:0050772"(positive regulation of axonogenesis)|go:"GO:0051223"(regulation of protein transport)|go:"GO:0051899"(membrane depolarization)|interpro:IPR030428	-	-	-	figure legend:st1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10116(rat-brain-cortex)|taxid:10116(Rattus norvegicus brain cortex)	-	2020/10/30	2020/10/30	rogid:DtE+ZXAZKdCMvUW5K+jXQ5bH07M10116	rogid:LXxIlR8jL+mLJ94McATz+sj4xF410116	rigid:3wclwrjZRvafcOruQOYnegkn54c	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q5XIE8	uniprotkb:B5D5N9	intact:EBI-15348306|ensembl:ENSRNOP00000023037	intact:EBI-15186164|ensembl:ENSRNOP00000015127|uniprotkb:B5D5P0	psi-mi:itm2b_rat(display_long)|uniprotkb:Itm2b(gene name)|psi-mi:Itm2b(display_short)|uniprotkb:Immature BRI2(gene name synonym)|uniprotkb:Transmembrane protein BRI(gene name synonym)	psi-mi:ctr2_rat(display_long)|uniprotkb:Low affinity cationic amino acid transporter 2(gene name synonym)|uniprotkb:Solute carrier family 7 member 2(gene name synonym)|uniprotkb:Slc7a2(gene name)|psi-mi:Slc7a2(display_short)|uniprotkb:Atrc2(gene name synonym)|uniprotkb:Cat2(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Martins et al. (2018)	imex:IM-28469|pubmed:29476059	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26439741|imex:IM-28469-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSRNOG00000016271(gene)|ensembl:ENSRNOT00000023037(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001540"(amyloid-beta binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0010008"(endosome membrane)|go:"GO:0030660"(Golgi-associated vesicle membrane)|go:"GO:0031301"(integral component of organelle membrane)|go:"GO:0042985"(negative regulation of amyloid precursor protein biosynthetic process)|interpro:IPR007084(BRICHOS)|interpro:IPR040145|mint:Q5XIE8|refseq:NP_001006964.1|rgd:620727	ensembl:ENSRNOT00000015127(transcript)|go:"GO:0000064"(L-ornithine transmembrane transporter activity)|go:"GO:0002537"(nitric oxide production involved in inflammatory response)|go:"GO:0005886"(plasma membrane)|go:"GO:0006809"(nitric oxide biosynthetic process)|go:"GO:0006865"(amino acid transport)|go:"GO:0015171"(amino acid transmembrane transporter activity)|ensembl:ENSRNOG00000011016(gene)|go:"GO:0015181"|go:"GO:0015189"(L-lysine transmembrane transporter activity)|go:"GO:0015809"|go:"GO:0016021"(integral component of membrane)|go:"GO:0030054"(cell junction)|go:"GO:0042116"(macrophage activation)|go:"GO:0043030"(regulation of macrophage activation)|go:"GO:0050727"(regulation of inflammatory response)|go:"GO:0061459"(L-arginine transmembrane transporter activity)|go:"GO:0097638"(L-arginine import across plasma membrane)|go:"GO:1902023"|go:"GO:1903352"(L-ornithine transmembrane transport)|interpro:IPR002293(Amino acid/polyamine transporter I)|interpro:IPR004755(Cationic amino acid transport permease)|interpro:IPR029485|mint:B5D5N9|reactome:R-RNO-352230|refseq:NP_001128158.1|refseq:NP_072141.2|rgd:68387	-	-	-	figure legend:st1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10116(rat-brain-cortex)|taxid:10116(Rattus norvegicus brain cortex)	-	2020/10/30	2020/10/30	rogid:DtE+ZXAZKdCMvUW5K+jXQ5bH07M10116	rogid:rhzF/yjx/SYNEDYtsLMV+3kXpEU10116	rigid:3wclwrjZRvafcOruQOYnegkn54c	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q5XIE8	uniprotkb:P15999	intact:EBI-15348306|ensembl:ENSRNOP00000023037	intact:EBI-916646|uniprotkb:Q6P753	psi-mi:itm2b_rat(display_long)|uniprotkb:Itm2b(gene name)|psi-mi:Itm2b(display_short)|uniprotkb:Immature BRI2(gene name synonym)|uniprotkb:Transmembrane protein BRI(gene name synonym)	psi-mi:atpa_rat(display_long)|uniprotkb:Atp5f1a(gene name)|psi-mi:Atp5f1a(display_short)|uniprotkb:ATP synthase F1 subunit alpha(gene name synonym)|uniprotkb:Atp5a1(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Martins et al. (2018)	imex:IM-28469|pubmed:29476059	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26439741|imex:IM-28469-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSRNOG00000016271(gene)|ensembl:ENSRNOT00000023037(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001540"(amyloid-beta binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0010008"(endosome membrane)|go:"GO:0030660"(Golgi-associated vesicle membrane)|go:"GO:0031301"(integral component of organelle membrane)|go:"GO:0042985"(negative regulation of amyloid precursor protein biosynthetic process)|interpro:IPR007084(BRICHOS)|interpro:IPR040145|mint:Q5XIE8|refseq:NP_001006964.1|rgd:620727	rgd:619993|refseq:NP_075581.1|interpro:IPR020003|interpro:IPR005294(ATPase, F1 complex, alpha subunit)|interpro:IPR023366|interpro:IPR000793(ATPase, F1/V1/A1 complex, alpha/beta subunit, C-terminal)|interpro:IPR004100(ATPase, F1/V1/A1 complex, alpha/beta subunit, N-terminal)|interpro:IPR000194(ATPase, F1/V1/A1 complex, alpha/beta subunit, nucleotide-binding)|interpro:IPR033732|interpro:IPR027417|mint:P15999|interpro:IPR038376|interpro:IPR036121|go:"GO:0000275"("mitochondrial proton-transporting ATP synthase complex, catalytic sector F(1)")|go:"GO:0001937"(negative regulation of endothelial cell proliferation)|go:"GO:0002020"(protease binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005753"(mitochondrial proton-transporting ATP synthase complex)|go:"GO:0005754"(mitochondrial proton-transporting ATP synthase, catalytic core)|go:"GO:0005886"(plasma membrane)|go:"GO:0006629"(lipid metabolic process)|go:"GO:0006754"(ATP biosynthetic process)|go:"GO:0006915"(apoptotic process)|go:"GO:0007568"(aging)|go:"GO:0009986"(cell surface)|go:"GO:0014850"(response to muscle activity)|go:"GO:0015986"(ATP synthesis coupled proton transport)|go:"GO:0016020"(membrane)|go:"GO:0042288"(MHC class I protein binding)|go:"GO:0042776"(mitochondrial ATP synthesis coupled proton transport)|go:"GO:0043531"(ADP binding)|go:"GO:0043532"(angiostatin binding)|go:"GO:0043536"(positive regulation of blood vessel endothelial cell migration)|go:"GO:0045121"(membrane raft)|go:"GO:0045259"(proton-transporting ATP synthase complex)|go:"GO:0045261"("proton-transporting ATP synthase complex, catalytic core F(1)")|go:"GO:0045471"(response to ethanol)|go:"GO:0046034"(ATP metabolic process)|go:"GO:0046933"(proton-transporting ATP synthase activity, rotational mechanism)|go:"GO:0071549"(cellular response to dexamethasone stimulus)|go:"GO:0071732"(cellular response to nitric oxide)|rcsb pdb:1MAB|rcsb pdb:2F43	-	-	-	figure legend:st1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10116(rat-brain-cortex)|taxid:10116(Rattus norvegicus brain cortex)	-	2020/10/30	2020/10/30	rogid:DtE+ZXAZKdCMvUW5K+jXQ5bH07M10116	rogid:Jkbhz0cHR3egHpKo/n1Ex4EbnUI10116	rigid:3wclwrjZRvafcOruQOYnegkn54c	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q5XIE8	uniprotkb:P19511	intact:EBI-15348306|ensembl:ENSRNOP00000023037	intact:EBI-2255901|ensembl:ENSRNOP00000021920|ensembl:ENSRNOP00000065147	psi-mi:itm2b_rat(display_long)|uniprotkb:Itm2b(gene name)|psi-mi:Itm2b(display_short)|uniprotkb:Immature BRI2(gene name synonym)|uniprotkb:Transmembrane protein BRI(gene name synonym)	psi-mi:at5f1_rat(display_long)|uniprotkb:Atp5pb(gene name)|psi-mi:Atp5pb(display_short)|uniprotkb:ATP synthase peripheral stalk-membrane subunit b(gene name synonym)|uniprotkb:ATP synthase subunit b(gene name synonym)|uniprotkb:Atp5f(gene name synonym)|uniprotkb:Atp5f1(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Martins et al. (2018)	imex:IM-28469|pubmed:29476059	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26439741|imex:IM-28469-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSRNOG00000016271(gene)|ensembl:ENSRNOT00000023037(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001540"(amyloid-beta binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0010008"(endosome membrane)|go:"GO:0030660"(Golgi-associated vesicle membrane)|go:"GO:0031301"(integral component of organelle membrane)|go:"GO:0042985"(negative regulation of amyloid precursor protein biosynthetic process)|interpro:IPR007084(BRICHOS)|interpro:IPR040145|mint:Q5XIE8|refseq:NP_001006964.1|rgd:620727	rgd:620041|refseq:NP_599192.1|refseq:XP_003749420.1|ensembl:ENSRNOG00000016000(gene)|ensembl:ENSRNOG00000046299(gene)|ensembl:ENSRNOT00000021920(transcript)|ensembl:ENSRNOT00000075083(transcript)|go:"GO:0000276"("mitochondrial proton-transporting ATP synthase complex, coupling factor F(o)")|go:"GO:0005753"(mitochondrial proton-transporting ATP synthase complex)|go:"GO:0015078"(proton transmembrane transporter activity)|go:"GO:0015986"(ATP synthesis coupled proton transport)|go:"GO:0042776"(mitochondrial ATP synthesis coupled proton transport)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0046034"(ATP metabolic process)|go:"GO:0071456"(cellular response to hypoxia)|interpro:IPR008688(ATPase, F0 complex, subunit B, mitochondrial)|interpro:IPR013837(ATPase, F0 complex subunit B, mitochondrial, metazoa)|mint:P19511|reactome:R-RNO-163210|reactome:R-RNO-8949613	-	-	-	figure legend:st1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10116(rat-brain-cortex)|taxid:10116(Rattus norvegicus brain cortex)	-	2020/10/30	2020/10/30	rogid:DtE+ZXAZKdCMvUW5K+jXQ5bH07M10116	rogid:QAiktmxMbugxEHz2O+zYw8oHMPk10116	rigid:3wclwrjZRvafcOruQOYnegkn54c	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q5XIE8	uniprotkb:P0C1X8	intact:EBI-15348306|ensembl:ENSRNOP00000023037	intact:EBI-26439554	psi-mi:itm2b_rat(display_long)|uniprotkb:Itm2b(gene name)|psi-mi:Itm2b(display_short)|uniprotkb:Immature BRI2(gene name synonym)|uniprotkb:Transmembrane protein BRI(gene name synonym)	psi-mi:aak1_rat(display_long)|uniprotkb:Aak1(gene name)|psi-mi:Aak1(display_short)|uniprotkb:Adaptor-associated kinase 1(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Martins et al. (2018)	imex:IM-28469|pubmed:29476059	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26439741|imex:IM-28469-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSRNOG00000016271(gene)|ensembl:ENSRNOT00000023037(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001540"(amyloid-beta binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0010008"(endosome membrane)|go:"GO:0030660"(Golgi-associated vesicle membrane)|go:"GO:0031301"(integral component of organelle membrane)|go:"GO:0042985"(negative regulation of amyloid precursor protein biosynthetic process)|interpro:IPR007084(BRICHOS)|interpro:IPR040145|mint:Q5XIE8|refseq:NP_001006964.1|rgd:620727	go:"GO:0005905"(clathrin-coated pit)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0006897"(endocytosis)|go:"GO:0019897"(extrinsic component of plasma membrane)|go:"GO:0031252"(cell leading edge)|go:"GO:0032880"(regulation of protein localization)|go:"GO:0035612"(AP-2 adaptor complex binding)|go:"GO:0043195"(terminal bouton)|go:"GO:0045747"(positive regulation of Notch signaling pathway)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0005112"(Notch binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0050821"(protein stabilization)|go:"GO:0071439"(clathrin complex)|go:"GO:0098793"(presynapse)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:2000369"(regulation of clathrin-dependent endocytosis)|reactome:R-RNO-8856825|reactome:R-RNO-8856828|mint:P0C1X8|interpro:IPR011009(Protein kinase-like)|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|rgd:1305520	-	-	-	figure legend:st1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10116(rat-brain-cortex)|taxid:10116(Rattus norvegicus brain cortex)	-	2020/10/30	2020/10/30	rogid:DtE+ZXAZKdCMvUW5K+jXQ5bH07M10116	rogid:C6WcpCL38oyfBD2aH90f1Y390so10116	rigid:3wclwrjZRvafcOruQOYnegkn54c	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q5XIE8	uniprotkb:P84092	intact:EBI-15348306|ensembl:ENSRNOP00000023037	intact:EBI-297693|uniprotkb:P53679|uniprotkb:P20172|ensembl:ENSRNOP00000070202	psi-mi:itm2b_rat(display_long)|uniprotkb:Itm2b(gene name)|psi-mi:Itm2b(display_short)|uniprotkb:Immature BRI2(gene name synonym)|uniprotkb:Transmembrane protein BRI(gene name synonym)	psi-mi:ap2m1_rat(display_long)|uniprotkb:Adaptor protein complex AP-2 subunit mu(gene name synonym)|uniprotkb:AP-2 mu chain(gene name synonym)|uniprotkb:Ap2m1(gene name)|psi-mi:Ap2m1(display_short)|uniprotkb:Mu2-adaptin(gene name synonym)|uniprotkb:Plasma membrane adaptor AP-2 50 kDa protein(gene name synonym)|uniprotkb:Clathrin coat assembly protein AP50(gene name synonym)|uniprotkb:Clathrin coat-associated protein AP50(gene name synonym)|uniprotkb:Clathrin assembly protein complex 2 mu medium chain(gene name synonym)|uniprotkb:Adaptor-related protein complex 2 subunit mu(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Martins et al. (2018)	imex:IM-28469|pubmed:29476059	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26439741|imex:IM-28469-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSRNOG00000016271(gene)|ensembl:ENSRNOT00000023037(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001540"(amyloid-beta binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0010008"(endosome membrane)|go:"GO:0030660"(Golgi-associated vesicle membrane)|go:"GO:0031301"(integral component of organelle membrane)|go:"GO:0042985"(negative regulation of amyloid precursor protein biosynthetic process)|interpro:IPR007084(BRICHOS)|interpro:IPR040145|mint:Q5XIE8|refseq:NP_001006964.1|rgd:620727	go:"GO:0098794"(postsynapse)|go:"GO:0098884"(postsynaptic neurotransmitter receptor internalization)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:1900244"(positive regulation of synaptic vesicle endocytosis)|go:"GO:1903077"(negative regulation of protein localization to plasma membrane)|interpro:IPR001392(Clathrin adaptor, mu subunit)|interpro:IPR011012(Longin-like)|interpro:IPR018240|interpro:IPR022775|interpro:IPR028565|interpro:IPR036168|interpro:IPR043512|interpro:IPR043532|mint:P84092|rcsb pdb:1BW8|rcsb pdb:1BXX|rcsb pdb:1HES|rcsb pdb:1I31|rcsb pdb:2BP5|rcsb pdb:2JKR|rcsb pdb:2JKT|rcsb pdb:2PR9|rcsb pdb:2VGL|rcsb pdb:2XA7|rcsb pdb:3H85|rcsb pdb:3ML6|rcsb pdb:4UQI|rcsb pdb:5C7Z|rcsb pdb:5FPI|rcsb pdb:5WRK|go:"GO:0097718"(disordered domain specific binding)|rcsb pdb:5WRL|rcsb pdb:5WRM|rcsb pdb:6QH5|rcsb pdb:6QH6|rcsb pdb:6RH6|rcsb pdb:6YAE|rcsb pdb:6YAF|rcsb pdb:6YAH|reactome:R-RNO-177504|reactome:R-RNO-190873|reactome:R-RNO-196025|reactome:R-RNO-2132295|reactome:R-RNO-416993|reactome:R-RNO-437239|reactome:R-RNO-5099900|reactome:R-RNO-5140745|reactome:R-RNO-8856825|reactome:R-RNO-8856828|reactome:R-RNO-8866427|reactome:R-RNO-8964038|ensembl:ENSRNOG00000001709(gene)|ensembl:ENSRNOT00000088821(transcript)|go:"GO:0002092"(positive regulation of receptor internalization)|go:"GO:0005048"(signal sequence binding)|go:"GO:0005886"(plasma membrane)|go:"GO:0005905"(clathrin-coated pit)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006897"(endocytosis)|go:"GO:0006900"(vesicle budding from membrane)|go:"GO:0008289"(lipid binding)|go:"GO:0016192"(vesicle-mediated transport)|go:"GO:0030122"(AP-2 adaptor complex)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0031623"(receptor internalization)|go:"GO:0035615"(clathrin adaptor activity)|go:"GO:0043195"(terminal bouton)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0048488"(synaptic vesicle endocytosis)|go:"GO:0050750"(low-density lipoprotein particle receptor binding)|go:"GO:0065003"(protein-containing complex assembly)|go:"GO:0072583"(clathrin-dependent endocytosis)|go:"GO:0097494"(regulation of vesicle size)|rgd:620135|refseq:NP_446289.1|dip:DIP-29761N	-	-	-	figure legend:st1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10116(rat-brain-cortex)|taxid:10116(Rattus norvegicus brain cortex)	-	2020/10/30	2020/10/30	rogid:DtE+ZXAZKdCMvUW5K+jXQ5bH07M10116	rogid:AyJEJTqzHtIRWEnMGBzLQP3H5lA10116	rigid:3wclwrjZRvafcOruQOYnegkn54c	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q5XIE8	uniprotkb:P52303	intact:EBI-15348306|ensembl:ENSRNOP00000023037	intact:EBI-1040277	psi-mi:itm2b_rat(display_long)|uniprotkb:Itm2b(gene name)|psi-mi:Itm2b(display_short)|uniprotkb:Immature BRI2(gene name synonym)|uniprotkb:Transmembrane protein BRI(gene name synonym)	psi-mi:ap1b1_rat(display_long)|uniprotkb:Ap1b1(gene name)|psi-mi:Ap1b1(display_short)|uniprotkb:Adtb1(gene name synonym)|uniprotkb:Adaptor protein complex AP-1 subunit beta-1(gene name synonym)|uniprotkb:Beta-adaptin 1(gene name synonym)|uniprotkb:Beta-1-adaptin(gene name synonym)|uniprotkb:Golgi adaptor HA1/AP1 adaptin beta subunit(gene name synonym)|uniprotkb:Clathrin assembly protein complex 1 beta large chain(gene name synonym)|uniprotkb:Adaptor-related protein complex 1 subunit beta-1(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Martins et al. (2018)	imex:IM-28469|pubmed:29476059	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26439741|imex:IM-28469-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSRNOG00000016271(gene)|ensembl:ENSRNOT00000023037(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001540"(amyloid-beta binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0010008"(endosome membrane)|go:"GO:0030660"(Golgi-associated vesicle membrane)|go:"GO:0031301"(integral component of organelle membrane)|go:"GO:0042985"(negative regulation of amyloid precursor protein biosynthetic process)|interpro:IPR007084(BRICHOS)|interpro:IPR040145|mint:Q5XIE8|refseq:NP_001006964.1|rgd:620727	interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR009028(Clathrin/coatomer adaptor, adaptin-like, appendage, C-terminal subdomain)|interpro:IPR002553(Clathrin/coatomer adaptor, adaptin-like, N-terminal)|interpro:IPR013041(Clathrin/coatomer adaptor, adaptin-like, appendage, Ig-like subdomain)|interpro:IPR008152(Clathrin adaptor, alpha/beta/gamma-adaptin, appendage, Ig-like subdomain)|interpro:IPR013037(Clathrin adaptor, beta-adaptin, appendage, Ig-like subdomain)|interpro:IPR015151(Clathrin adaptor, beta-adaptin, appendage, C-terminal subdomain)|rgd:2064|refseq:NP_058973.1|interpro:IPR016342(Adaptor protein complex, beta subunit)|go:"GO:0001822"(kidney development)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0007368"(determination of left/right symmetry)|go:"GO:0007507"(heart development)|go:"GO:0016192"(vesicle-mediated transport)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030118"(clathrin coat)|go:"GO:0030131"(clathrin adaptor complex)|go:"GO:0030276"(clathrin binding)|go:"GO:0030665"(clathrin-coated vesicle membrane)|go:"GO:0048268"(clathrin coat assembly)|rcsb pdb:1W63|reactome:R-RNO-2132295|reactome:R-RNO-432720|reactome:R-RNO-432722|interpro:IPR026739|interpro:IPR012295(Beta2-adaptin/TATA-box binding, C-terminal)|mint:P52303	-	-	-	figure legend:st1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10116(rat-brain-cortex)|taxid:10116(Rattus norvegicus brain cortex)	-	2020/10/30	2020/10/30	rogid:DtE+ZXAZKdCMvUW5K+jXQ5bH07M10116	rogid:oi419FYkBH5Us8n9O9r2j+OvHkM10116	rigid:3wclwrjZRvafcOruQOYnegkn54c	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q5XIE8	uniprotkb:P04764	intact:EBI-15348306|ensembl:ENSRNOP00000023037	intact:EBI-915852|uniprotkb:Q66HI3|uniprotkb:Q6AYV3|uniprotkb:Q6P504|ensembl:ENSRNOP00000024106|ensembl:ENSRNOP00000073191	psi-mi:itm2b_rat(display_long)|uniprotkb:Itm2b(gene name)|psi-mi:Itm2b(display_short)|uniprotkb:Immature BRI2(gene name synonym)|uniprotkb:Transmembrane protein BRI(gene name synonym)	psi-mi:enoa_rat(display_long)|uniprotkb:2-phospho-D-glycerate hydro-lyase(gene name synonym)|uniprotkb:Non-neural enolase(gene name synonym)|uniprotkb:Enolase 1(gene name synonym)|uniprotkb:Eno1(gene name)|psi-mi:Eno1(display_short)|uniprotkb:Eno-1(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Martins et al. (2018)	imex:IM-28469|pubmed:29476059	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26439741|imex:IM-28469-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSRNOG00000016271(gene)|ensembl:ENSRNOT00000023037(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001540"(amyloid-beta binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0010008"(endosome membrane)|go:"GO:0030660"(Golgi-associated vesicle membrane)|go:"GO:0031301"(integral component of organelle membrane)|go:"GO:0042985"(negative regulation of amyloid precursor protein biosynthetic process)|interpro:IPR007084(BRICHOS)|interpro:IPR040145|mint:Q5XIE8|refseq:NP_001006964.1|rgd:620727	rgd:2553|refseq:NP_001103378.1|refseq:NP_036686.2|ensembl:ENSRNOG00000017895(gene)|ensembl:ENSRNOT00000024106(transcript)|ensembl:ENSRNOT00000081579(transcript)|go:"GO:0000015"(phosphopyruvate hydratase complex)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000287"(magnesium ion binding)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0003723"(RNA binding)|go:"GO:0004634"(phosphopyruvate hydratase activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006096"(glycolytic process)|go:"GO:0009615"(response to virus)|go:"GO:0009986"(cell surface)|go:"GO:0010756"(positive regulation of plasminogen activation)|go:"GO:0016020"(membrane)|go:"GO:0019897"(extrinsic component of plasma membrane)|go:"GO:0019899"(enzyme binding)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0030426"(growth cone)|go:"GO:0031072"(heat shock protein binding)|go:"GO:0032889"(regulation of vacuole fusion, non-autophagic)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043005"(neuron projection)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045121"(membrane raft)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045933"(positive regulation of muscle contraction)|go:"GO:0051020"(GTPase binding)|go:"GO:0051099"(positive regulation of binding)|go:"GO:0061621"(canonical glycolysis)|go:"GO:0070371"(ERK1 and ERK2 cascade)|go:"GO:0071456"(cellular response to hypoxia)|go:"GO:0097060"(synaptic membrane)|go:"GO:0098761"(cellular response to interleukin-7)|go:"GO:0099738"(cell cortex region)|go:"GO:1903298"(negative regulation of hypoxia-induced intrinsic apoptotic signaling pathway)|go:"GO:2001171"(positive regulation of ATP biosynthetic process)|interpro:IPR000941(Enolase)|interpro:IPR020809|interpro:IPR020810|interpro:IPR020811|interpro:IPR029017|interpro:IPR036849|mint:P04764|reactome:R-RNO-70171|reactome:R-RNO-70263	-	-	-	figure legend:st1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10116(rat-brain-cortex)|taxid:10116(Rattus norvegicus brain cortex)	-	2020/10/30	2020/10/30	rogid:DtE+ZXAZKdCMvUW5K+jXQ5bH07M10116	rogid:JPjYBxy1gOmhfZso6+adhg5N8UM10116	rigid:3wclwrjZRvafcOruQOYnegkn54c	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q5XIE8	uniprotkb:P61751	intact:EBI-15348306|ensembl:ENSRNOP00000023037	intact:EBI-917907|uniprotkb:P36403|ensembl:ENSRNOP00000017692	psi-mi:itm2b_rat(display_long)|uniprotkb:Itm2b(gene name)|psi-mi:Itm2b(display_short)|uniprotkb:Immature BRI2(gene name synonym)|uniprotkb:Transmembrane protein BRI(gene name synonym)	psi-mi:arf4_rat(display_long)|uniprotkb:Arf4(gene name)|psi-mi:Arf4(display_short)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Martins et al. (2018)	imex:IM-28469|pubmed:29476059	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26439741|imex:IM-28469-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSRNOG00000016271(gene)|ensembl:ENSRNOT00000023037(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001540"(amyloid-beta binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0010008"(endosome membrane)|go:"GO:0030660"(Golgi-associated vesicle membrane)|go:"GO:0031301"(integral component of organelle membrane)|go:"GO:0042985"(negative regulation of amyloid precursor protein biosynthetic process)|interpro:IPR007084(BRICHOS)|interpro:IPR040145|mint:Q5XIE8|refseq:NP_001006964.1|rgd:620727	rgd:621275|refseq:NP_077065.1|ensembl:ENSRNOG00000012623(gene)|ensembl:ENSRNOT00000017692(transcript)|go:"GO:0003924"(GTPase activity)|go:"GO:0005154"(epidermal growth factor receptor binding)|go:"GO:0005525"(GTP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006471"(protein ADP-ribosylation)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006890"(retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum)|go:"GO:0007173"(epidermal growth factor receptor signaling pathway)|go:"GO:0007420"(brain development)|go:"GO:0007612"(learning)|go:"GO:0016192"(vesicle-mediated transport)|go:"GO:0016477"(cell migration)|go:"GO:0031584"(activation of phospholipase D activity)|go:"GO:0032587"(ruffle membrane)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043197"(dendritic spine)|go:"GO:0045176"(apical protein localization)|go:"GO:0045197"(establishment or maintenance of epithelial cell apical/basal polarity)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048678"(response to axon injury)|go:"GO:0050807"(regulation of synapse organization)|go:"GO:0060996"(dendritic spine development)|go:"GO:0061512"(protein localization to cilium)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099175"(regulation of postsynapse organization)|go:"GO:2000377"(regulation of reactive oxygen species metabolic process)|interpro:IPR005225(Small GTP-binding protein)|interpro:IPR006689(ARF/SAR superfamily)|interpro:IPR027417|mint:P61751|reactome:R-RNO-5620916|reactome:R-RNO-6807878|reactome:R-RNO-6811434	-	-	-	figure legend:st1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10116(rat-brain-cortex)|taxid:10116(Rattus norvegicus brain cortex)	-	2020/10/30	2020/10/30	rogid:DtE+ZXAZKdCMvUW5K+jXQ5bH07M10116	rogid:UQ8GuyD6go1ZCYpUU69uTevxoVo10116	rigid:3wclwrjZRvafcOruQOYnegkn54c	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q5XIE8	uniprotkb:Q09073	intact:EBI-15348306|ensembl:ENSRNOP00000023037	intact:EBI-918254|ensembl:ENSRNOP00000015913	psi-mi:itm2b_rat(display_long)|uniprotkb:Itm2b(gene name)|psi-mi:Itm2b(display_short)|uniprotkb:Immature BRI2(gene name synonym)|uniprotkb:Transmembrane protein BRI(gene name synonym)	psi-mi:adt2_rat(display_long)|uniprotkb:Slc25a5(gene name)|psi-mi:Slc25a5(display_short)|uniprotkb:Ant2(gene name synonym)|uniprotkb:Adenine nucleotide translocator 2(gene name synonym)|uniprotkb:ADP,ATP carrier protein 2(gene name synonym)|uniprotkb:Solute carrier family 25 member 5(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Martins et al. (2018)	imex:IM-28469|pubmed:29476059	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26439741|imex:IM-28469-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSRNOG00000016271(gene)|ensembl:ENSRNOT00000023037(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001540"(amyloid-beta binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0010008"(endosome membrane)|go:"GO:0030660"(Golgi-associated vesicle membrane)|go:"GO:0031301"(integral component of organelle membrane)|go:"GO:0042985"(negative regulation of amyloid precursor protein biosynthetic process)|interpro:IPR007084(BRICHOS)|interpro:IPR040145|mint:Q5XIE8|refseq:NP_001006964.1|rgd:620727	rgd:620353|refseq:NP_476443.1|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005757"(mitochondrial permeability transition pore complex)|go:"GO:0007059"(chromosome segregation)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0015078"(proton transmembrane transporter activity)|go:"GO:0016020"(membrane)|go:"GO:0017077"(oxidative phosphorylation uncoupler activity)|go:"GO:0030183"(B cell differentiation)|go:"GO:0030218"(erythrocyte differentiation)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0042645"(mitochondrial nucleoid)|go:"GO:0045121"(membrane raft)|go:"GO:0046902"(regulation of mitochondrial membrane permeability)|go:"GO:0051503"(adenine nucleotide transport)|go:"GO:0071817"(MMXD complex)|go:"GO:0140021"(mitochondrial ADP transmembrane transport)|go:"GO:1901029"(negative regulation of mitochondrial outer membrane permeabilization involved in apoptotic signaling pathway)|go:"GO:1901526"(positive regulation of mitophagy)|go:"GO:1990544"(mitochondrial ATP transmembrane transport)|go:"GO:1990830"(cellular response to leukemia inhibitory factor)|go:"GO:1990845"(adaptive thermogenesis)|interpro:IPR002067(Mitochondrial carrier protein)|interpro:IPR002113(Adenine nucleotide translocator 1)|interpro:IPR018108|interpro:IPR023395|mint:Q09073|reactome:R-RNO-83936|go:"GO:0005471"("ATP:ADP antiporter activity")|ensembl:ENSRNOG00000039980(gene)|ensembl:ENSRNOT00000015085(transcript)|go:"GO:0000295"(adenine nucleotide transmembrane transporter activity)	-	-	-	figure legend:st1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10116(rat-brain-cortex)|taxid:10116(Rattus norvegicus brain cortex)	-	2020/10/30	2020/10/30	rogid:DtE+ZXAZKdCMvUW5K+jXQ5bH07M10116	rogid:WdaA9kTxHaJrlP00OIJCP15jMpI10116	rigid:3wclwrjZRvafcOruQOYnegkn54c	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q5XIE8	uniprotkb:Q05962	intact:EBI-15348306|ensembl:ENSRNOP00000023037	intact:EBI-918169	psi-mi:itm2b_rat(display_long)|uniprotkb:Itm2b(gene name)|psi-mi:Itm2b(display_short)|uniprotkb:Immature BRI2(gene name synonym)|uniprotkb:Transmembrane protein BRI(gene name synonym)	psi-mi:adt1_rat(display_long)|uniprotkb:Adenine nucleotide translocator 1(gene name synonym)|uniprotkb:ADP,ATP carrier protein 1(gene name synonym)|uniprotkb:Solute carrier family 25 member 4(gene name synonym)|uniprotkb:Slc25a4(gene name)|psi-mi:Slc25a4(display_short)|uniprotkb:Ant1(gene name synonym)|uniprotkb:Aac1(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Martins et al. (2018)	imex:IM-28469|pubmed:29476059	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26439741|imex:IM-28469-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSRNOG00000016271(gene)|ensembl:ENSRNOT00000023037(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001540"(amyloid-beta binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0010008"(endosome membrane)|go:"GO:0030660"(Golgi-associated vesicle membrane)|go:"GO:0031301"(integral component of organelle membrane)|go:"GO:0042985"(negative regulation of amyloid precursor protein biosynthetic process)|interpro:IPR007084(BRICHOS)|interpro:IPR040145|mint:Q5XIE8|refseq:NP_001006964.1|rgd:620727	rgd:620352|refseq:NP_445967.1|interpro:IPR002113(Adenine nucleotide translocator 1)|interpro:IPR002067(Mitochondrial carrier protein)|interpro:IPR018108|interpro:IPR023395|mint:Q05962|go:"GO:0001889"(liver development)|go:"GO:0005471"("ATP:ADP antiporter activity")|go:"GO:0005739"(mitochondrion)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005757"(mitochondrial permeability transition pore complex)|go:"GO:0007507"(heart development)|go:"GO:0007568"(aging)|go:"GO:0008637"(apoptotic mitochondrial changes)|go:"GO:0010667"(negative regulation of cardiac muscle cell apoptotic process)|go:"GO:0015078"(proton transmembrane transporter activity)|go:"GO:0015866"(ADP transport)|go:"GO:0016020"(membrane)|go:"GO:0017077"(oxidative phosphorylation uncoupler activity)|go:"GO:0019899"(enzyme binding)|go:"GO:0032592"(integral component of mitochondrial membrane)|go:"GO:0045121"(membrane raft)|go:"GO:0046902"(regulation of mitochondrial membrane permeability)|go:"GO:0060546"(negative regulation of necroptotic process)|go:"GO:0061051"(positive regulation of cell growth involved in cardiac muscle cell development)|go:"GO:0070555"(response to interleukin-1)|go:"GO:0140021"(mitochondrial ADP transmembrane transport)|go:"GO:1901526"(positive regulation of mitophagy)|go:"GO:1902109"(negative regulation of mitochondrial membrane permeability involved in apoptotic process)|go:"GO:1990544"(mitochondrial ATP transmembrane transport)|go:"GO:1990845"(adaptive thermogenesis)|go:"GO:2000277"(positive regulation of oxidative phosphorylation uncoupler activity)|reactome:R-RNO-83936	-	-	-	figure legend:st1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10116(rat-brain-cortex)|taxid:10116(Rattus norvegicus brain cortex)	-	2020/10/30	2020/10/30	rogid:DtE+ZXAZKdCMvUW5K+jXQ5bH07M10116	rogid:NA6aO99oqoOE7rPf9y3s7zKx6HM10116	rigid:3wclwrjZRvafcOruQOYnegkn54c	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q5XIE8	uniprotkb:P52481	intact:EBI-15348306|ensembl:ENSRNOP00000023037	intact:EBI-26439519|ensembl:ENSRNOP00000062591|ensembl:ENSRNOP00000074020	psi-mi:itm2b_rat(display_long)|uniprotkb:Itm2b(gene name)|psi-mi:Itm2b(display_short)|uniprotkb:Immature BRI2(gene name synonym)|uniprotkb:Transmembrane protein BRI(gene name synonym)	psi-mi:cap2_rat(display_long)|uniprotkb:Cap2(gene name)|psi-mi:Cap2(display_short)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Martins et al. (2018)	imex:IM-28469|pubmed:29476059	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26439741|imex:IM-28469-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSRNOG00000016271(gene)|ensembl:ENSRNOT00000023037(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001540"(amyloid-beta binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0010008"(endosome membrane)|go:"GO:0030660"(Golgi-associated vesicle membrane)|go:"GO:0031301"(integral component of organelle membrane)|go:"GO:0042985"(negative regulation of amyloid precursor protein biosynthetic process)|interpro:IPR007084(BRICHOS)|interpro:IPR040145|mint:Q5XIE8|refseq:NP_001006964.1|rgd:620727	go:"GO:0045761"(regulation of adenylate cyclase activity)|interpro:IPR001837(Adenylate cyclase-associated CAP)|interpro:IPR006599(CARP motif)|interpro:IPR013912(Adenylate cyclase-associated CAP,  C-terminal)|interpro:IPR013992(Adenylate cyclase-associated CAP, N-terminal)|interpro:IPR016098(Cyclase-associated protein CAP/septum formation inhibitor MinC, C-terminal)|interpro:IPR017901|interpro:IPR018106|interpro:IPR028417|interpro:IPR028418|interpro:IPR036222|interpro:IPR036223|mint:P52481|ensembl:ENSRNOG00000043350(gene)|ensembl:ENSRNOT00000065742(transcript)|ensembl:ENSRNOT00000078992(transcript)|go:"GO:0000902"(cell morphogenesis)|go:"GO:0003779"(actin binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0007010"(cytoskeleton organization)|go:"GO:0008179"(adenylate cyclase binding)|go:"GO:0014069"(postsynaptic density)|go:"GO:0019933"(cAMP-mediated signaling)|go:"GO:0030036"(actin cytoskeleton organization)|go:"GO:0042802"(identical protein binding)|refseq:NP_446326.1|refseq:XP_006253815.1|refseq:XP_006253816.1|rgd:620310	-	-	-	figure legend:st1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10116(rat-brain-cortex)|taxid:10116(Rattus norvegicus brain cortex)	-	2020/10/30	2020/10/30	rogid:DtE+ZXAZKdCMvUW5K+jXQ5bH07M10116	rogid:V6JzOsegnaJ3Ijkh/+y2oE/9jcU10116	rigid:3wclwrjZRvafcOruQOYnegkn54c	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)
uniprotkb:Q5XIE8	uniprotkb:P63039	intact:EBI-15348306|ensembl:ENSRNOP00000023037	intact:EBI-432091|uniprotkb:P19226|uniprotkb:P19227|uniprotkb:P97602|ensembl:ENSRNOP00000063666	psi-mi:itm2b_rat(display_long)|uniprotkb:Itm2b(gene name)|psi-mi:Itm2b(display_short)|uniprotkb:Immature BRI2(gene name synonym)|uniprotkb:Transmembrane protein BRI(gene name synonym)	psi-mi:ch60_rat(display_long)|uniprotkb:Heat shock protein 60(gene name synonym)|uniprotkb:60 kDa chaperonin(gene name synonym)|uniprotkb:Chaperonin 60(gene name synonym)|uniprotkb:Mitochondrial matrix protein P1(gene name synonym)|uniprotkb:HSP-65(gene name synonym)|uniprotkb:Hspd1(gene name)|psi-mi:Hspd1(display_short)|uniprotkb:Hsp60(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Martins et al. (2018)	imex:IM-28469|pubmed:29476059	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	taxid:10116(rat)|taxid:10116("Rattus norvegicus (Rat)")	psi-mi:"MI:0914"(association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26439741|imex:IM-28469-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSRNOG00000016271(gene)|ensembl:ENSRNOT00000023037(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001540"(amyloid-beta binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0010008"(endosome membrane)|go:"GO:0030660"(Golgi-associated vesicle membrane)|go:"GO:0031301"(integral component of organelle membrane)|go:"GO:0042985"(negative regulation of amyloid precursor protein biosynthetic process)|interpro:IPR007084(BRICHOS)|interpro:IPR040145|mint:Q5XIE8|refseq:NP_001006964.1|rgd:620727	rgd:621314|refseq:NP_071565.2|refseq:XP_006244994.1|go:"GO:0034185"(apolipoprotein binding)|go:"GO:0034186"(apolipoprotein A-I binding)|go:"GO:0034514"(mitochondrial unfolded protein response)|go:"GO:0034605"(cellular response to heat)|go:"GO:0042026"(protein refolding)|go:"GO:0042100"(B cell proliferation)|go:"GO:0042110"(T cell activation)|go:"GO:0042113"(B cell activation)|go:"GO:0042220"(response to cocaine)|go:"GO:0042493"|go:"GO:0042542"(response to hydrogen peroxide)|go:"GO:0042588"(zymogen granule)|go:"GO:0043032"(positive regulation of macrophage activation)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0043627"(response to estrogen)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045041"(protein import into mitochondrial intermembrane space)|go:"GO:0045121"(membrane raft)|go:"GO:0046696"(lipopolysaccharide receptor complex)|go:"GO:0048291"(isotype switching to IgG isotypes)|go:"GO:0050729"(positive regulation of inflammatory response)|go:"GO:0050821"(protein stabilization)|go:"GO:0050870"(positive regulation of T cell activation)|go:"GO:0051087"(chaperone binding)|go:"GO:0051384"(response to glucocorticoid)|go:"GO:0051702"(biological process involved in interaction with symbiont)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071866"(negative regulation of apoptotic process in bone marrow cell)|go:"GO:0097225"(sperm midpiece)|go:"GO:0098761"(cellular response to interleukin-7)|go:"GO:0140030"(modification-dependent protein binding)|go:"GO:1903427"(negative regulation of reactive oxygen species biosynthetic process)|interpro:IPR001844(Chaperonin Cpn60)|interpro:IPR002423(Chaperonin Cpn60/TCP-1)|interpro:IPR018370|interpro:IPR027409|interpro:IPR027410|interpro:IPR027413|mint:P63039|reactome:R-RNO-1268020|ensembl:ENSRNOG00000014525(gene)|ensembl:ENSRNOT00000066589(transcript)|go:"GO:0001530"(lipopolysaccharide binding)|go:"GO:0001666"(response to hypoxia)|go:"GO:0002039"(p53 binding)|go:"GO:0002755"(MyD88-dependent toll-like receptor signaling pathway)|go:"GO:0002842"(positive regulation of T cell mediated immune response to tumor cell)|go:"GO:0002931"(response to ischemia)|go:"GO:0003725"(double-stranded RNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0005769"(early endosome)|go:"GO:0005782"(peroxisomal matrix)|go:"GO:0005791"(rough endoplasmic reticulum)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005905"(clathrin-coated pit)|go:"GO:0006457"(protein folding)|go:"GO:0006458"('de novo' protein folding)|go:"GO:0006919"(activation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0006986"(response to unfolded protein)|go:"GO:0008035"(high-density lipoprotein particle binding)|go:"GO:0008637"(apoptotic mitochondrial changes)|go:"GO:0009408"(response to heat)|go:"GO:0009409"(response to cold)|go:"GO:0009986"(cell surface)|go:"GO:0010033"(response to organic substance)|go:"GO:0014070"(response to organic cyclic compound)|go:"GO:0014823"(response to activity)|go:"GO:0016020"(membrane)|go:"GO:0016853"(isomerase activity)|go:"GO:0019899"(enzyme binding)|go:"GO:0030061"(mitochondrial crista)|go:"GO:0030135"(coated vesicle)|go:"GO:0030141"(secretory granule)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0031985"(Golgi cisterna)|go:"GO:0032496"(response to lipopolysaccharide)|go:"GO:0032727"(positive regulation of interferon-alpha production)|go:"GO:0032729"(positive regulation of interferon-gamma production)|go:"GO:0032733"(positive regulation of interleukin-10 production)|go:"GO:0032735"(positive regulation of interleukin-12 production)|go:"GO:0032755"(positive regulation of interleukin-6 production)|go:"GO:0032760"(positive regulation of tumor necrosis factor production)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033198"(response to ATP)	-	-	-	figure legend:st1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10116(rat-brain-cortex)|taxid:10116(Rattus norvegicus brain cortex)	-	2020/10/30	2020/10/30	rogid:DtE+ZXAZKdCMvUW5K+jXQ5bH07M10116	rogid:WD1fQLh4I0ovpakE8KtM1R0XpL410116	rigid:3wclwrjZRvafcOruQOYnegkn54c	false	-	-	-	-	psi-mi:"MI:0102"(sequence tag identification)	psi-mi:"MI:0102"(sequence tag identification)