#ID(s) interactor A	ID(s) interactor B	Alt. ID(s) interactor A	Alt. ID(s) interactor B	Alias(es) interactor A	Alias(es) interactor B	Interaction detection method(s)	Publication 1st author(s)	Publication Identifier(s)	Taxid interactor A	Taxid interactor B	Interaction type(s)	Source database(s)	Interaction identifier(s)	Confidence value(s)	Expansion method(s)	Biological role(s) interactor A	Biological role(s) interactor B	Experimental role(s) interactor A	Experimental role(s) interactor B	Type(s) interactor A	Type(s) interactor B	Xref(s) interactor A	Xref(s) interactor B	Interaction Xref(s)	Annotation(s) interactor A	Annotation(s) interactor B	Interaction annotation(s)	Host organism(s)	Interaction parameter(s)	Creation date	Update date	Checksum(s) interactor A	Checksum(s) interactor B	Interaction Checksum(s)	Negative	Feature(s) interactor A	Feature(s) interactor B	Stoichiometry(s) interactor A	Stoichiometry(s) interactor B	Identification method participant A	Identification method participant B
uniprotkb:Q494U1	uniprotkb:Q5ZXN6	intact:EBI-10241513|uniprotkb:Q5SV98|uniprotkb:Q9H0M7|uniprotkb:Q494U2|ensembl:ENSP00000368720	intact:EBI-26359852|ensemblbacteria:AAU26784	psi-mi:pkhn1_human(display_long)|uniprotkb:PLEKHN1(gene name)|psi-mi:PLEKHN1(display_short)|uniprotkb:CLPABP(gene name synonym)|uniprotkb:Cardiolipin and phosphatidic acid-binding protein(gene name synonym)	psi-mi:ankx_legph(display_long)|uniprotkb:ankX(gene name)|psi-mi:ankX(display_short)|uniprotkb:legA8(gene name synonym)|uniprotkb:lpg0695(locus name)|uniprotkb:Ankyrin repeat-containing protein X(gene name synonym)	psi-mi:"MI:0089"(protein array)	Yu et al. (2018)	imex:IM-28385|pubmed:29433439	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:272624(legph)|taxid:272624(Legionella pneumophila subsp. pneumophila)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26359874|imex:IM-28385-41	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001153656.1|refseq:NP_115505.2|ensembl:ENSG00000187583(gene)|ensembl:ENST00000379410(transcript)|go:"GO:0001666"(response to hypoxia)|go:"GO:0001786"(phosphatidylserine binding)|go:"GO:0005739"(mitochondrion)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005886"(plasma membrane)|go:"GO:0031966"(mitochondrial membrane)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0061158"(3'-UTR-mediated mRNA destabilization)|go:"GO:0070300"(phosphatidic acid binding)|go:"GO:1901612"(cardiolipin binding)|go:"GO:1901981"(phosphatidylinositol phosphate binding)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR037839|interpro:IPR042835|ensembl:ENST00000379407|ensembl:ENSP00000368717|ensembl:ENST00000379409|ensembl:ENSP00000368719|ensembl:ENSP00000368720	ensemblbacteria:AAU26784(transcript)|ensemblbacteria:lpg0695(gene)|go:"GO:0005576"(extracellular region)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0043087"(regulation of GTPase activity)|go:"GO:0044605"(phosphocholine transferase activity)|rcsb pdb:6SKU|refseq:YP_094731.1|rcsb pdb:4BEP|rcsb pdb:4BER|rcsb pdb:4BES|rcsb pdb:4BET|interpro:IPR002110(Ankyrin)|interpro:IPR020683|interpro:IPR036770|interpro:IPR003812(Filamentation induced by cAMP protein Fic)|interpro:IPR036597	-	-	-	figure legend:f1b f1c|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2020/09/28	2020/09/28	rogid:TB3sgI04Vl/d2WNLkD7OPwSjCqQ9606	rogid:97DncqzHYB0l66zqkQj9On5h/nU272624	rigid:1uxx4uEPyNwYJcw3/83CAxKXY/E	false	glutathione s tranferase tag:?-?	fluorescent protein tag:c-c	-	-	psi-mi:"MI:0867"(tag visualisation by fluorescence)	psi-mi:"MI:0867"(tag visualisation by fluorescence)
uniprotkb:Q86WP2	uniprotkb:Q5ZXN6	intact:EBI-2349758|uniprotkb:A6NKW3|uniprotkb:Q6NSH6|uniprotkb:Q9H785|uniprotkb:Q9H0D4|uniprotkb:Q9NSN4|intact:EBI-28972285|ensembl:ENSP00000421202	intact:EBI-26359852|ensemblbacteria:AAU26784	psi-mi:gpbp1_human(display_long)|uniprotkb:GPBP1(gene name)|psi-mi:GPBP1(display_short)|uniprotkb:GPBP(gene name synonym)|uniprotkb:SSH6(gene name synonym)|uniprotkb:GC-rich promoter-binding protein 1(gene name synonym)|uniprotkb:Vascular wall-linked protein(gene name synonym)	psi-mi:ankx_legph(display_long)|uniprotkb:ankX(gene name)|psi-mi:ankX(display_short)|uniprotkb:legA8(gene name synonym)|uniprotkb:lpg0695(locus name)|uniprotkb:Ankyrin repeat-containing protein X(gene name synonym)	psi-mi:"MI:0089"(protein array)	Yu et al. (2018)	imex:IM-28385|pubmed:29433439	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:272624(legph)|taxid:272624(Legionella pneumophila subsp. pneumophila)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26359945|imex:IM-28385-43	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENST00000264779|ensembl:ENSP00000264779|ensembl:ENSP00000421202|ensembl:ENST00000511209|ensembl:ENSP00000422337|ensembl:ENST00000514387|ensembl:ENSP00000421709|refseq:NP_001120707.2|refseq:NP_001120708.1|refseq:NP_001190175.1|refseq:NP_075064.1|refseq:XP_016865245.1|refseq:XP_016865246.1|refseq:XP_016865247.1|refseq:XP_016865248.1|ensembl:ENSG00000062194(gene)|ensembl:ENST00000506184(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|interpro:IPR028128|mint:Q86WP2	ensemblbacteria:AAU26784(transcript)|ensemblbacteria:lpg0695(gene)|go:"GO:0005576"(extracellular region)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0043087"(regulation of GTPase activity)|go:"GO:0044605"(phosphocholine transferase activity)|rcsb pdb:6SKU|refseq:YP_094731.1|rcsb pdb:4BEP|rcsb pdb:4BER|rcsb pdb:4BES|rcsb pdb:4BET|interpro:IPR002110(Ankyrin)|interpro:IPR020683|interpro:IPR036770|interpro:IPR003812(Filamentation induced by cAMP protein Fic)|interpro:IPR036597	-	-	-	figure legend:f1b f1c|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2020/09/28	2020/09/28	rogid:YpnFRXC1FDOxqNl2Dq67tJRNO6o9606	rogid:97DncqzHYB0l66zqkQj9On5h/nU272624	rigid:yoCB7W4qY4K+QGhpLysXJUQnOYo	false	glutathione s tranferase tag:?-?	fluorescent protein tag:c-c	-	-	psi-mi:"MI:0867"(tag visualisation by fluorescence)	psi-mi:"MI:0867"(tag visualisation by fluorescence)
uniprotkb:P98187	uniprotkb:Q5ZXN6	intact:EBI-1049983|ensembl:ENSP00000477567	intact:EBI-26359852|ensemblbacteria:AAU26784	psi-mi:cp4f8_human(display_long)|uniprotkb:CYPIVF8(gene name synonym)|uniprotkb:CYP4F8(gene name)|psi-mi:CYP4F8(display_short)	psi-mi:ankx_legph(display_long)|uniprotkb:ankX(gene name)|psi-mi:ankX(display_short)|uniprotkb:legA8(gene name synonym)|uniprotkb:lpg0695(locus name)|uniprotkb:Ankyrin repeat-containing protein X(gene name synonym)	psi-mi:"MI:0089"(protein array)	Yu et al. (2018)	imex:IM-28385|pubmed:29433439	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:272624(legph)|taxid:272624(Legionella pneumophila subsp. pneumophila)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26359954|imex:IM-28385-21	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_009184.1|ensembl:ENSG00000186526(gene)|ensembl:ENST00000612078(transcript)|go:"GO:0004497"(monooxygenase activity)|go:"GO:0005506"(iron ion binding)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006690"(icosanoid metabolic process)|go:"GO:0006693"(prostaglandin metabolic process)|go:"GO:0016021"(integral component of membrane)|go:"GO:0018685"(alkane 1-monooxygenase activity)|go:"GO:0020037"(heme binding)|go:"GO:0070330"(aromatase activity)|interpro:IPR001128(Cytochrome P450)|interpro:IPR002401(Cytochrome P450, E-class, group I)|interpro:IPR017972|interpro:IPR036396|reactome:R-HSA-211935|reactome:R-HSA-211979|reactome:R-HSA-2142691	ensemblbacteria:AAU26784(transcript)|ensemblbacteria:lpg0695(gene)|go:"GO:0005576"(extracellular region)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0043087"(regulation of GTPase activity)|go:"GO:0044605"(phosphocholine transferase activity)|rcsb pdb:6SKU|refseq:YP_094731.1|rcsb pdb:4BEP|rcsb pdb:4BER|rcsb pdb:4BES|rcsb pdb:4BET|interpro:IPR002110(Ankyrin)|interpro:IPR020683|interpro:IPR036770|interpro:IPR003812(Filamentation induced by cAMP protein Fic)|interpro:IPR036597	-	-	-	figure legend:f1b f1c|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2020/09/28	2020/09/28	rogid:Um8FlQYWmjdBW61eG5LNPDdBaW89606	rogid:97DncqzHYB0l66zqkQj9On5h/nU272624	rigid:JgQoImfijVJ7Z+lN2b3n6JkoKLc	false	glutathione s tranferase tag:?-?	fluorescent protein tag:c-c	-	-	psi-mi:"MI:0867"(tag visualisation by fluorescence)	psi-mi:"MI:0867"(tag visualisation by fluorescence)
uniprotkb:Q9H4M7	uniprotkb:Q5ZXN6	intact:EBI-716549|uniprotkb:Q8N4M8|uniprotkb:Q8N658|ensembl:ENSP00000263265	intact:EBI-26359852|ensemblbacteria:AAU26784	psi-mi:pkha4_human(display_long)|uniprotkb:Phosphoinositol 3-phosphate-binding protein 1(gene name synonym)|uniprotkb:PLEKHA4(gene name)|psi-mi:PLEKHA4(display_short)|uniprotkb:PEPP1(gene name synonym)	psi-mi:ankx_legph(display_long)|uniprotkb:ankX(gene name)|psi-mi:ankX(display_short)|uniprotkb:legA8(gene name synonym)|uniprotkb:lpg0695(locus name)|uniprotkb:Ankyrin repeat-containing protein X(gene name synonym)	psi-mi:"MI:0089"(protein array)	Yu et al. (2018)	imex:IM-28385|pubmed:29433439	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:272624(legph)|taxid:272624(Legionella pneumophila subsp. pneumophila)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26359964|imex:IM-28385-1	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001154826.1|refseq:NP_065955.2|ensembl:ENSG00000105559(gene)|ensembl:ENST00000263265(transcript)|go:"GO:0005546"(phosphatidylinositol-4,5-bisphosphate binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0031234"(extrinsic component of cytoplasmic side of plasma membrane)|go:"GO:0032266"(phosphatidylinositol-3-phosphate binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0043325"(phosphatidylinositol-3,4-bisphosphate binding)|go:"GO:0080025"(phosphatidylinositol-3,5-bisphosphate binding)|go:"GO:0090263"(positive regulation of canonical Wnt signaling pathway)|go:"GO:2000096"(positive regulation of Wnt signaling pathway, planar cell polarity pathway)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR040392|rcsb pdb:1UPQ|rcsb pdb:1UPR|reactome:R-HSA-1660499	ensemblbacteria:AAU26784(transcript)|ensemblbacteria:lpg0695(gene)|go:"GO:0005576"(extracellular region)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0043087"(regulation of GTPase activity)|go:"GO:0044605"(phosphocholine transferase activity)|rcsb pdb:6SKU|refseq:YP_094731.1|rcsb pdb:4BEP|rcsb pdb:4BER|rcsb pdb:4BES|rcsb pdb:4BET|interpro:IPR002110(Ankyrin)|interpro:IPR020683|interpro:IPR036770|interpro:IPR003812(Filamentation induced by cAMP protein Fic)|interpro:IPR036597	-	-	-	figure legend:f1b f1c|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2020/09/28	2020/09/28	rogid:gBeBdIcJIF2fJe6r+Ea2gmiKiTQ9606	rogid:97DncqzHYB0l66zqkQj9On5h/nU272624	rigid:4j4JG3yIkSI9dmUv8ce3lOioauU	false	glutathione s tranferase tag:?-?	fluorescent protein tag:c-c	-	-	psi-mi:"MI:0867"(tag visualisation by fluorescence)	psi-mi:"MI:0867"(tag visualisation by fluorescence)
uniprotkb:Q8N3F8	uniprotkb:Q5ZXN6	intact:EBI-1056885|uniprotkb:Q5TI16|uniprotkb:Q7RTP5|uniprotkb:Q8N3N8|uniprotkb:Q9BVL9|uniprotkb:Q9BY92|uniprotkb:Q9UH43|uniprotkb:Q9UH44|uniprotkb:Q9UH45|ensembl:ENSP00000215957	intact:EBI-26359852|ensemblbacteria:AAU26784	psi-mi:milk1_human(display_long)|uniprotkb:MICALL1(gene name)|psi-mi:MICALL1(display_short)|uniprotkb:KIAA1668(gene name synonym)|uniprotkb:MIRAB13(gene name synonym)|uniprotkb:Molecule interacting with Rab13(gene name synonym)	psi-mi:ankx_legph(display_long)|uniprotkb:ankX(gene name)|psi-mi:ankX(display_short)|uniprotkb:legA8(gene name synonym)|uniprotkb:lpg0695(locus name)|uniprotkb:Ankyrin repeat-containing protein X(gene name synonym)	psi-mi:"MI:0089"(protein array)	Yu et al. (2018)	imex:IM-28385|pubmed:29433439	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:272624(legph)|taxid:272624(Legionella pneumophila subsp. pneumophila)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26359973|imex:IM-28385-3	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_203744.1|ensembl:ENSP00000215957|ensembl:ENSG00000100139(gene)|ensembl:ENST00000215957(transcript)|go:"GO:0005770"(late endosome)|go:"GO:0006612"(protein targeting to membrane)|go:"GO:0006897"(endocytosis)|go:"GO:0006898"(receptor-mediated endocytosis)|go:"GO:0019898"(extrinsic component of membrane)|go:"GO:0031175"(neuron projection development)|go:"GO:0031267"(small GTPase binding)|go:"GO:0031902"(late endosome membrane)|go:"GO:0032456"(endocytic recycling)|go:"GO:0032458"(slow endocytic recycling)|go:"GO:0036010"(protein localization to endosome)|go:"GO:0042802"(identical protein binding)|go:"GO:0046872"(metal ion binding)|go:"GO:0055038"(recycling endosome membrane)|go:"GO:0070300"(phosphatidic acid binding)|go:"GO:0097320"(plasma membrane tubulation)|go:"GO:1990090"(cellular response to nerve growth factor stimulus)|interpro:IPR001715(Calponin-like actin-binding)|interpro:IPR001781(Zinc finger, LIM-type)|interpro:IPR022735|interpro:IPR028563|interpro:IPR036872|mint:Q8N3F8|rcsb pdb:2KSP|go:"GO:0045296"(cadherin binding)	ensemblbacteria:AAU26784(transcript)|ensemblbacteria:lpg0695(gene)|go:"GO:0005576"(extracellular region)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0043087"(regulation of GTPase activity)|go:"GO:0044605"(phosphocholine transferase activity)|rcsb pdb:6SKU|refseq:YP_094731.1|rcsb pdb:4BEP|rcsb pdb:4BER|rcsb pdb:4BES|rcsb pdb:4BET|interpro:IPR002110(Ankyrin)|interpro:IPR020683|interpro:IPR036770|interpro:IPR003812(Filamentation induced by cAMP protein Fic)|interpro:IPR036597	-	-	-	figure legend:f1b f1c|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2020/09/28	2020/09/28	rogid:G64P9EtjEfLIVLYkb+w3vCWaT0w9606	rogid:97DncqzHYB0l66zqkQj9On5h/nU272624	rigid:PdqN5Q9YlDA7F6QLubEzzeNF/0I	false	glutathione s tranferase tag:?-?	fluorescent protein tag:c-c	-	-	psi-mi:"MI:0867"(tag visualisation by fluorescence)	psi-mi:"MI:0867"(tag visualisation by fluorescence)
uniprotkb:P22694	uniprotkb:Q5ZXN6	intact:EBI-2679622|uniprotkb:Q14VH1|uniprotkb:Q5BNF3|uniprotkb:Q96B09|uniprotkb:Q59GC0|uniprotkb:Q5BNF2|uniprotkb:Q8IYR5|uniprotkb:Q8IZQ0|uniprotkb:Q5BNE9|uniprotkb:B4E2Q1|uniprotkb:Q7Z3M1|uniprotkb:Q5BNF1|uniprotkb:Q5CZ92|uniprotkb:Q5T1K3|uniprotkb:Q5BNF0|uniprotkb:B4DKB0|uniprotkb:B1APG4|ensembl:ENSP00000359723	intact:EBI-26359852|ensemblbacteria:AAU26784	psi-mi:kapcb_human(display_long)|uniprotkb:PRKACB(gene name)|psi-mi:PRKACB(display_short)	psi-mi:ankx_legph(display_long)|uniprotkb:ankX(gene name)|psi-mi:ankX(display_short)|uniprotkb:legA8(gene name synonym)|uniprotkb:lpg0695(locus name)|uniprotkb:Ankyrin repeat-containing protein X(gene name synonym)	psi-mi:"MI:0089"(protein array)	Yu et al. (2018)	imex:IM-28385|pubmed:29433439	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:272624(legph)|taxid:272624(Legionella pneumophila subsp. pneumophila)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26359983|imex:IM-28385-45	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001229786.1|refseq:NP_001229787.1|refseq:NP_001229788.1|refseq:NP_001229789.1|refseq:NP_001229790.1|refseq:NP_001229791.1|refseq:NP_002722.1|refseq:NP_891993.1|refseq:NP_997461.1|refseq:XP_005271076.1|refseq:XP_006710821.1|refseq:NP_001287844.1|refseq:NP_001287845.1|refseq:NP_001287846.1|ensembl:ENSG00000142875(gene)|ensembl:ENST00000370689(transcript)|go:"GO:0000287"(magnesium ion binding)|go:"GO:0001843"(neural tube closure)|go:"GO:0003091"(renal water homeostasis)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0004679"(AMP-activated protein kinase activity)|go:"GO:0004691"(cAMP-dependent protein kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005952"(cAMP-dependent protein kinase complex)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0007165"(signal transduction)|go:"GO:0007188"(adenylate cyclase-modulating G protein-coupled receptor signaling pathway)|go:"GO:0010737"(protein kinase A signaling)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0034380"(high-density lipoprotein particle assembly)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051447"(negative regulation of meiotic cell cycle)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070613"(regulation of protein processing)|go:"GO:0097338"(response to clozapine)|go:"GO:0097546"(ciliary base)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:1901621"(negative regulation of smoothened signaling pathway involved in dorsal/ventral neural tube patterning)|interpro:IPR000719(Protein kinase, core)|interpro:IPR000961(Protein kinase, C-terminal)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|mint:P22694|interpro:IPR044109|reactome:R-HSA-111931|reactome:R-HSA-163358|reactome:R-HSA-163560|reactome:R-HSA-163615|reactome:R-HSA-164378|reactome:R-HSA-180024|reactome:R-HSA-381676|reactome:R-HSA-392517|reactome:R-HSA-422356|reactome:R-HSA-432040|reactome:R-HSA-4420097|reactome:R-HSA-442720|reactome:R-HSA-5610780|reactome:R-HSA-5610783|reactome:R-HSA-5610785|reactome:R-HSA-5610787|reactome:R-HSA-5621575|reactome:R-HSA-5687128|reactome:R-HSA-8853659|reactome:R-HSA-8963896|reactome:R-HSA-9010642|reactome:R-HSA-9634600|reactome:R-HSA-9660821|reactome:R-HSA-9664323|reactome:R-HSA-983231	ensemblbacteria:AAU26784(transcript)|ensemblbacteria:lpg0695(gene)|go:"GO:0005576"(extracellular region)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0043087"(regulation of GTPase activity)|go:"GO:0044605"(phosphocholine transferase activity)|rcsb pdb:6SKU|refseq:YP_094731.1|rcsb pdb:4BEP|rcsb pdb:4BER|rcsb pdb:4BES|rcsb pdb:4BET|interpro:IPR002110(Ankyrin)|interpro:IPR020683|interpro:IPR036770|interpro:IPR003812(Filamentation induced by cAMP protein Fic)|interpro:IPR036597	-	-	-	figure legend:f1b f1c|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2020/09/28	2020/09/28	rogid:FEzsjRJZlkFu5+KK4abzu7oAY9E9606	rogid:97DncqzHYB0l66zqkQj9On5h/nU272624	rigid:Z46Kic97YEwgZpQB7Chbbt2DGCQ	false	glutathione s tranferase tag:?-?	fluorescent protein tag:c-c	-	-	psi-mi:"MI:0867"(tag visualisation by fluorescence)	psi-mi:"MI:0867"(tag visualisation by fluorescence)
uniprotkb:Q16643	uniprotkb:Q5ZXN6	intact:EBI-351394|uniprotkb:Q9UFZ5|uniprotkb:B2RBG0|ensembl:ENSP00000308532|intact:EBI-4404710|uniprotkb:A8MV58	intact:EBI-26359852|ensemblbacteria:AAU26784	psi-mi:dreb_human(display_long)|uniprotkb:DBN1(gene name)|psi-mi:DBN1(display_short)|uniprotkb:Developmentally-regulated brain protein(gene name synonym)|uniprotkb:D0S117E(gene name synonym)	psi-mi:ankx_legph(display_long)|uniprotkb:ankX(gene name)|psi-mi:ankX(display_short)|uniprotkb:legA8(gene name synonym)|uniprotkb:lpg0695(locus name)|uniprotkb:Ankyrin repeat-containing protein X(gene name synonym)	psi-mi:"MI:0089"(protein array)	Yu et al. (2018)	imex:IM-28385|pubmed:29433439	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:272624(legph)|taxid:272624(Legionella pneumophila subsp. pneumophila)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26359991|imex:IM-28385-23	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_004386.2|refseq:NP_543157.1|refseq:XP_005265884.1|ensembl:ENSG00000113758(gene)|ensembl:ENST00000309007(transcript)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0003779"(actin binding)|go:"GO:0005522"(profilin binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005886"(plasma membrane)|go:"GO:0005921"(gap junction)|go:"GO:0007015"(actin filament organization)|go:"GO:0010643"(cell communication by chemical coupling)|go:"GO:0010644"(cell communication by electrical coupling)|go:"GO:0014069"(postsynaptic density)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0030027"(lamellipodium)|go:"GO:0042641"(actomyosin)|go:"GO:0030425"(dendrite)|go:"GO:0045211"(postsynaptic membrane)|go:"GO:0045296"(cadherin binding)|go:"GO:0045773"(positive regulation of axon extension)|go:"GO:0048168"(regulation of neuronal synaptic plasticity)|go:"GO:0048812"(neuron projection morphogenesis)|go:"GO:0050773"(regulation of dendrite development)|go:"GO:0051015"(actin filament binding)|go:"GO:0051220"(cytoplasmic sequestering of protein)|go:"GO:0061003"(positive regulation of dendritic spine morphogenesis)|go:"GO:0061351"(neural precursor cell proliferation)|go:"GO:0098974"(postsynaptic actin cytoskeleton organization)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099524"(postsynaptic cytosol)|go:"GO:1902685"(positive regulation of receptor localization to synapse)|interpro:IPR002108(Actin-binding, cofilin/tropomyosin type)|interpro:IPR028438|interpro:IPR029006|mint:Q16643|go:"GO:0030426"(growth cone)|go:"GO:0030427"(site of polarized growth)|go:"GO:0030833"(regulation of actin filament polymerization)|go:"GO:0030863"(cortical cytoskeleton)|go:"GO:0030864"(cortical actin cytoskeleton)|go:"GO:0031915"(positive regulation of synaptic plasticity)|rcsb pdb:5Y1Z|rcsb pdb:5ZZ9|reactome:R-HSA-9013405|reactome:R-HSA-9013407|reactome:R-HSA-9013418|reactome:R-HSA-9013422|go:"GO:0032507"(maintenance of protein location in cell)|refseq:XP_016864629.1	ensemblbacteria:AAU26784(transcript)|ensemblbacteria:lpg0695(gene)|go:"GO:0005576"(extracellular region)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0043087"(regulation of GTPase activity)|go:"GO:0044605"(phosphocholine transferase activity)|rcsb pdb:6SKU|refseq:YP_094731.1|rcsb pdb:4BEP|rcsb pdb:4BER|rcsb pdb:4BES|rcsb pdb:4BET|interpro:IPR002110(Ankyrin)|interpro:IPR020683|interpro:IPR036770|interpro:IPR003812(Filamentation induced by cAMP protein Fic)|interpro:IPR036597	-	-	-	figure legend:f1b f1c|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2020/09/28	2020/09/28	rogid:0+VPJM5mTuG2jzmzGG3iLswmCUc9606	rogid:97DncqzHYB0l66zqkQj9On5h/nU272624	rigid:CGwPknqU4eHKHXnRabmn3CoiTzI	false	glutathione s tranferase tag:?-?	fluorescent protein tag:c-c	-	-	psi-mi:"MI:0867"(tag visualisation by fluorescence)	psi-mi:"MI:0867"(tag visualisation by fluorescence)
uniprotkb:Q8TBK6	uniprotkb:Q5ZXN6	intact:EBI-597063|uniprotkb:Q9NXR4|ensembl:ENSP00000423276	intact:EBI-26359852|ensemblbacteria:AAU26784	psi-mi:zch10_human(display_long)|uniprotkb:ZCCHC10(gene name)|psi-mi:ZCCHC10(display_short)	psi-mi:ankx_legph(display_long)|uniprotkb:ankX(gene name)|psi-mi:ankX(display_short)|uniprotkb:legA8(gene name synonym)|uniprotkb:lpg0695(locus name)|uniprotkb:Ankyrin repeat-containing protein X(gene name synonym)	psi-mi:"MI:0089"(protein array)	Yu et al. (2018)	imex:IM-28385|pubmed:29433439	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:272624(legph)|taxid:272624(Legionella pneumophila subsp. pneumophila)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26359999|imex:IM-28385-5	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_060135.1|refseq:NP_001287746.1|refseq:NP_001287747.1|refseq:NP_001287748.1|refseq:NP_001287751.1|refseq:NP_001295056.1|refseq:NP_001295057.1|refseq:NP_001295058.1|refseq:NP_001295059.1|refseq:NP_001287745.1|ensembl:ENSG00000155329(gene)|ensembl:ENST00000509437(transcript)|go:"GO:0003676"(nucleic acid binding)|go:"GO:0008270"(zinc ion binding)|interpro:IPR036875|interpro:IPR039715	ensemblbacteria:AAU26784(transcript)|ensemblbacteria:lpg0695(gene)|go:"GO:0005576"(extracellular region)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0043087"(regulation of GTPase activity)|go:"GO:0044605"(phosphocholine transferase activity)|rcsb pdb:6SKU|refseq:YP_094731.1|rcsb pdb:4BEP|rcsb pdb:4BER|rcsb pdb:4BES|rcsb pdb:4BET|interpro:IPR002110(Ankyrin)|interpro:IPR020683|interpro:IPR036770|interpro:IPR003812(Filamentation induced by cAMP protein Fic)|interpro:IPR036597	-	-	-	figure legend:f1b f1c|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2020/09/28	2020/09/28	rogid:WcCfa6tnoaA9NGta4vXKUY3VnxI9606	rogid:97DncqzHYB0l66zqkQj9On5h/nU272624	rigid:cs0Xb4fA7s1jnHDY4jttm7GTZsw	false	glutathione s tranferase tag:?-?	fluorescent protein tag:c-c	-	-	psi-mi:"MI:0867"(tag visualisation by fluorescence)	psi-mi:"MI:0867"(tag visualisation by fluorescence)
uniprotkb:P98170	uniprotkb:Q494U1	intact:EBI-517127|uniprotkb:Q9NQ14|uniprotkb:D3DTF2|ensembl:ENSP00000347858|ensembl:ENSP00000360242|ensembl:ENSP00000395230	intact:EBI-10241513|uniprotkb:Q5SV98|uniprotkb:Q9H0M7|uniprotkb:Q494U2|ensembl:ENSP00000368720	psi-mi:xiap_human(display_long)|uniprotkb:Inhibitor of apoptosis protein 3(gene name synonym)|uniprotkb:X-linked inhibitor of apoptosis protein(gene name synonym)|uniprotkb:IAP-like protein(gene name synonym)|uniprotkb:XIAP(gene name)|psi-mi:XIAP(display_short)|uniprotkb:API3(gene name synonym)|uniprotkb:IAP3(gene name synonym)|uniprotkb:BIRC4(gene name synonym)|uniprotkb:Baculoviral IAP repeat-containing protein 4(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase XIAP(gene name synonym)	psi-mi:pkhn1_human(display_long)|uniprotkb:PLEKHN1(gene name)|psi-mi:PLEKHN1(display_short)|uniprotkb:CLPABP(gene name synonym)|uniprotkb:Cardiolipin and phosphatidic acid-binding protein(gene name synonym)	psi-mi:"MI:0089"(protein array)	Yu et al. (2018)	imex:IM-28385|pubmed:29433439	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26361169|imex:IM-28385-49	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:XP_006724817.1|refseq:NP_001158.2|refseq:NP_001191330.1|refseq:XP_011529631.1|dip:DIP-27626N|ensembl:ENSG00000101966(gene)|ensembl:ENST00000355640(transcript)|ensembl:ENST00000371199(transcript)|ensembl:ENST00000434753(transcript)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005876"(spindle microtubule)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0030510"(regulation of BMP signaling pathway)|go:"GO:0031398"(positive regulation of protein ubiquitination)|go:"GO:0042127"(regulation of cell population proliferation)|go:"GO:0042802"(identical protein binding)|go:"GO:0043027"(cysteine-type endopeptidase inhibitor activity involved in apoptotic process)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043154"(negative regulation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0045088"(regulation of innate immune response)|go:"GO:0046872"(metal ion binding)|go:"GO:0050727"(regulation of inflammatory response)|go:"GO:0051402"(neuron apoptotic process)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0055070"(copper ion homeostasis)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0070424"(regulation of nucleotide-binding oligomerization domain containing signaling pathway)|go:"GO:0090263"(positive regulation of canonical Wnt signaling pathway)|go:"GO:1902530"(positive regulation of protein linear polyubiquitination)|go:"GO:1990001"(inhibition of cysteine-type endopeptidase activity involved in apoptotic process)|interpro:IPR001370(Proteinase inhibitor I32, inhibitor of apoptosis)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR011029(DEATH-like)|interpro:IPR042579|mint:P98170|rcsb pdb:1C9Q|rcsb pdb:1F9X|rcsb pdb:1G3F|rcsb pdb:1G73|rcsb pdb:1I3O|rcsb pdb:1I4O|rcsb pdb:1I51|rcsb pdb:1KMC|rcsb pdb:1NW9|rcsb pdb:1TFQ|rcsb pdb:1TFT|rcsb pdb:2ECG|rcsb pdb:2JK7|rcsb pdb:2KNA|rcsb pdb:2OPY|rcsb pdb:2OPZ|rcsb pdb:2POI|rcsb pdb:2POP|rcsb pdb:2QRA|rcsb pdb:2VSL|rcsb pdb:3CLX|rcsb pdb:3CM2|rcsb pdb:3CM7|rcsb pdb:3EYL|rcsb pdb:3G76|rcsb pdb:3HL5|rcsb pdb:3UW4|rcsb pdb:3UW5|rcsb pdb:4EC4|rcsb pdb:4HY0|rcsb pdb:4IC2|rcsb pdb:4IC3|rcsb pdb:4J3Y|rcsb pdb:4J44|rcsb pdb:4J45|rcsb pdb:4J46|rcsb pdb:4J47|rcsb pdb:4J48|rcsb pdb:4KJU|rcsb pdb:4KJV|rcsb pdb:4KMP|rcsb pdb:4MTZ|rcsb pdb:4OXC|rcsb pdb:4WVS|rcsb pdb:4WVT|rcsb pdb:4WVU|rcsb pdb:5C0K|rcsb pdb:5C0L|rcsb pdb:5C3H|rcsb pdb:5C3K|rcsb pdb:5C7A|rcsb pdb:5C7B|rcsb pdb:5C7C|rcsb pdb:5C7D|rcsb pdb:5C83|rcsb pdb:5C84|rcsb pdb:5M6E|rcsb pdb:5M6F|rcsb pdb:5M6H|rcsb pdb:5M6L|rcsb pdb:5M6M|rcsb pdb:5O6T|rcsb pdb:5OQW|rcsb pdb:6EY2|rcsb pdb:6GJW|rcsb pdb:6QCI|reactome:R-HSA-111459|reactome:R-HSA-111463|reactome:R-HSA-111464|reactome:R-HSA-111469|reactome:R-HSA-3769402|reactome:R-HSA-5213460|reactome:R-HSA-5357905|reactome:R-HSA-5357956|reactome:R-HSA-5675482|reactome:R-HSA-8948747|reactome:R-HSA-8948751|reactome:R-HSA-9627069	refseq:NP_001153656.1|refseq:NP_115505.2|ensembl:ENSG00000187583(gene)|ensembl:ENST00000379410(transcript)|go:"GO:0001666"(response to hypoxia)|go:"GO:0001786"(phosphatidylserine binding)|go:"GO:0005739"(mitochondrion)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005886"(plasma membrane)|go:"GO:0031966"(mitochondrial membrane)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0061158"(3'-UTR-mediated mRNA destabilization)|go:"GO:0070300"(phosphatidic acid binding)|go:"GO:1901612"(cardiolipin binding)|go:"GO:1901981"(phosphatidylinositol phosphate binding)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR037839|interpro:IPR042835|ensembl:ENST00000379407|ensembl:ENSP00000368717|ensembl:ENST00000379409|ensembl:ENSP00000368719|ensembl:ENSP00000368720	-	-	-	figure legend:SF7|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2020/09/28	2020/09/28	rogid:6eDcOay+c2ZmIAD/pwnCDROBwgM9606	rogid:TB3sgI04Vl/d2WNLkD7OPwSjCqQ9606	rigid:NcIXxSyI8mE2oDkWFFDZ/9KElqE	false	glutathione s tranferase tag:c-c	fluorescent protein tag:c-c	-	-	psi-mi:"MI:0867"(tag visualisation by fluorescence)	psi-mi:"MI:0867"(tag visualisation by fluorescence)
uniprotkb:Q9P286	uniprotkb:Q494U1	intact:EBI-741896|ensembl:ENSP00000322957|ensembl:ENSP00000367679|ensembl:ENSP00000367686|intact:EBI-1051061|uniprotkb:A8K5T6|uniprotkb:D3DW14|uniprotkb:Q5W115|uniprotkb:Q8TB93|uniprotkb:Q9BX09|uniprotkb:Q9ULF6	intact:EBI-10241513|uniprotkb:Q5SV98|uniprotkb:Q9H0M7|uniprotkb:Q494U2|ensembl:ENSP00000368720	psi-mi:pak5_human(display_long)|uniprotkb:PAK5(gene name)|psi-mi:PAK5(display_short)|uniprotkb:KIAA1264(gene name synonym)|uniprotkb:PAK7(gene name synonym)|uniprotkb:p21-activated kinase 5(gene name synonym)|uniprotkb:p21-activated kinase 7(gene name synonym)	psi-mi:pkhn1_human(display_long)|uniprotkb:PLEKHN1(gene name)|psi-mi:PLEKHN1(display_short)|uniprotkb:CLPABP(gene name synonym)|uniprotkb:Cardiolipin and phosphatidic acid-binding protein(gene name synonym)	psi-mi:"MI:0089"(protein array)	Yu et al. (2018)	imex:IM-28385|pubmed:29433439	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26361177|imex:IM-28385-15	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000101349(gene)|go:"GO:0045202"(synapse)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:2001237"(negative regulation of extrinsic apoptotic signaling pathway)|interpro:IPR000095(PAK-box/P21-Rho-binding)|interpro:IPR000719(Protein kinase, core)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR028754|interpro:IPR033923|interpro:IPR036936|rcsb pdb:2F57|reactome:R-HSA-428540|reactome:R-HSA-9013148|reactome:R-HSA-9013149|reactome:R-HSA-9013405|reactome:R-HSA-9013407|go:"GO:0043408"(regulation of MAPK cascade)|ensembl:ENST00000353224(transcript)|ensembl:ENST00000378423(transcript)|ensembl:ENST00000378429(transcript)|go:"GO:0001558"(regulation of cell growth)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0006915"(apoptotic process)|go:"GO:0007010"(cytoskeleton organization)|go:"GO:0007165"(signal transduction)|go:"GO:0007612"(learning)|go:"GO:0007613"(memory)|go:"GO:0007626"(locomotory behavior)|go:"GO:0008283"(cell population proliferation)|go:"GO:0016477"(cell migration)|go:"GO:0032147"(activation of protein kinase activity)|go:"GO:0035556"(intracellular signal transduction)|refseq:NP_065074.1|refseq:NP_817127.1|refseq:XP_016883449.1|refseq:XP_016883450.1|refseq:XP_016883451.1|refseq:XP_016883452.1|refseq:XP_016883453.1|refseq:XP_016883454.1	refseq:NP_001153656.1|refseq:NP_115505.2|ensembl:ENSG00000187583(gene)|ensembl:ENST00000379410(transcript)|go:"GO:0001666"(response to hypoxia)|go:"GO:0001786"(phosphatidylserine binding)|go:"GO:0005739"(mitochondrion)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005886"(plasma membrane)|go:"GO:0031966"(mitochondrial membrane)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0061158"(3'-UTR-mediated mRNA destabilization)|go:"GO:0070300"(phosphatidic acid binding)|go:"GO:1901612"(cardiolipin binding)|go:"GO:1901981"(phosphatidylinositol phosphate binding)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR037839|interpro:IPR042835|ensembl:ENST00000379407|ensembl:ENSP00000368717|ensembl:ENST00000379409|ensembl:ENSP00000368719|ensembl:ENSP00000368720	-	-	-	figure legend:SF7|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2020/09/28	2020/09/28	rogid:xxNDwmHn4jv8toBmviGjFwBU32E9606	rogid:TB3sgI04Vl/d2WNLkD7OPwSjCqQ9606	rigid:ba0jw8YQtZqOishDNTOVbJFYqE0	false	glutathione s tranferase tag:c-c	fluorescent protein tag:c-c	-	-	psi-mi:"MI:0867"(tag visualisation by fluorescence)	psi-mi:"MI:0867"(tag visualisation by fluorescence)
uniprotkb:Q9NWF9	uniprotkb:Q494U1	intact:EBI-723313|uniprotkb:Q6Y691|uniprotkb:Q75ML7|uniprotkb:Q7Z2H7|uniprotkb:Q7Z7C1|uniprotkb:Q8NHW7|uniprotkb:Q9NYT1|ensembl:ENSP00000404602	intact:EBI-10241513|uniprotkb:Q5SV98|uniprotkb:Q9H0M7|uniprotkb:Q494U2|ensembl:ENSP00000368720	psi-mi:rn216_human(display_long)|uniprotkb:TRIAD3(gene name synonym)|uniprotkb:UBCE7IP1(gene name synonym)|uniprotkb:RING finger protein 216(gene name synonym)|uniprotkb:Ubiquitin-conjugating enzyme 7-interacting protein 1(gene name synonym)|uniprotkb:Zinc finger protein inhibiting NF-kappa-B(gene name synonym)|uniprotkb:Triad domain-containing protein 3(gene name synonym)|uniprotkb:RNF216(gene name)|psi-mi:RNF216(display_short)|uniprotkb:ZIN(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase RNF216(gene name synonym)	psi-mi:pkhn1_human(display_long)|uniprotkb:PLEKHN1(gene name)|psi-mi:PLEKHN1(display_short)|uniprotkb:CLPABP(gene name synonym)|uniprotkb:Cardiolipin and phosphatidic acid-binding protein(gene name synonym)	psi-mi:"MI:0089"(protein array)	Yu et al. (2018)	imex:IM-28385|pubmed:29433439	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26361185|imex:IM-28385-35	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_996994.1|refseq:NP_996999.1|ensembl:ENSG00000011275(gene)|ensembl:ENST00000425013(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0032480"(negative regulation of type I interferon production)|go:"GO:0032648"(regulation of interferon-beta production)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0046872"(metal ion binding)|go:"GO:0006915"(apoptotic process)|go:"GO:0050691"(regulation of defense response to virus by host)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0070936"(protein K48-linked ubiquitination)|go:"GO:0098685"(Schaffer collateral - CA1 synapse)|go:"GO:0098843"(postsynaptic endocytic zone)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099546"(protein catabolic process, modulating synaptic transmission)|interpro:IPR002867(Zinc finger, C6HC-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR044066|reactome:R-HSA-936440|refseq:XP_011513738.1|refseq:XP_005249842.1|refseq:XP_016867852.1|refseq:XP_016867854.1	refseq:NP_001153656.1|refseq:NP_115505.2|ensembl:ENSG00000187583(gene)|ensembl:ENST00000379410(transcript)|go:"GO:0001666"(response to hypoxia)|go:"GO:0001786"(phosphatidylserine binding)|go:"GO:0005739"(mitochondrion)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005886"(plasma membrane)|go:"GO:0031966"(mitochondrial membrane)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0061158"(3'-UTR-mediated mRNA destabilization)|go:"GO:0070300"(phosphatidic acid binding)|go:"GO:1901612"(cardiolipin binding)|go:"GO:1901981"(phosphatidylinositol phosphate binding)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR037839|interpro:IPR042835|ensembl:ENST00000379407|ensembl:ENSP00000368717|ensembl:ENST00000379409|ensembl:ENSP00000368719|ensembl:ENSP00000368720	-	-	-	figure legend:SF7|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2020/09/28	2020/09/28	rogid:IrD/snISVEoKM7Mej6ufGnrokTc9606	rogid:TB3sgI04Vl/d2WNLkD7OPwSjCqQ9606	rigid:JSz36wcLyq73tR+G0EdSvGGvzlA	false	glutathione s tranferase tag:c-c	fluorescent protein tag:c-c	-	-	psi-mi:"MI:0867"(tag visualisation by fluorescence)	psi-mi:"MI:0867"(tag visualisation by fluorescence)
uniprotkb:Q9H7X0	uniprotkb:Q494U1	intact:EBI-12260336|ensembl:ENSP00000385903|ensembl:ENSP00000393224|ensembl:ENSP00000458667|ensembl:ENSP00000458928|ensembl:ENSP00000459057|ensembl:ENSP00000497411|ensembl:ENSP00000497988|uniprotkb:B3KRQ0|uniprotkb:B4DLZ0|uniprotkb:B4DPZ8|uniprotkb:B4DYC4|uniprotkb:D3DUC2|uniprotkb:E7EQ65|uniprotkb:Q6IA31|uniprotkb:Q6UX26	intact:EBI-10241513|uniprotkb:Q5SV98|uniprotkb:Q9H0M7|uniprotkb:Q494U2|ensembl:ENSP00000368720	psi-mi:naa60_human(display_long)|uniprotkb:NAA60(gene name)|psi-mi:NAA60(display_short)|uniprotkb:HAT4(gene name synonym)|uniprotkb:Histone acetyltransferase type B protein 4(gene name synonym)|uniprotkb:N-acetyltransferase 15(gene name synonym)|uniprotkb:NAT15(gene name synonym)|uniprotkb:UNQ2771/PRO7155(orf name)|uniprotkb:N-alpha-acetyltransferase F(gene name synonym)	psi-mi:pkhn1_human(display_long)|uniprotkb:PLEKHN1(gene name)|psi-mi:PLEKHN1(display_short)|uniprotkb:CLPABP(gene name synonym)|uniprotkb:Cardiolipin and phosphatidic acid-binding protein(gene name synonym)	psi-mi:"MI:0089"(protein array)	Yu et al. (2018)	imex:IM-28385|pubmed:29433439	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26361193|imex:IM-28385-17	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000122390(gene)|go:"GO:0006334"(nucleosome assembly)|go:"GO:0006474"(N-terminal protein amino acid acetylation)|go:"GO:0007059"(chromosome segregation)|go:"GO:0008283"(cell population proliferation)|go:"GO:0010485"(H4 histone acetyltransferase activity)|go:"GO:0017196"(N-terminal peptidyl-methionine acetylation)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043966"(histone H3 acetylation)|go:"GO:0043967"(histone H4 acetylation)|interpro:IPR000182(GCN5-related N-acetyltransferase)|interpro:IPR016181(Acyl-CoA N-acyltransferase)|rcsb pdb:5HGZ|rcsb pdb:5HH0|rcsb pdb:5HH1|rcsb pdb:5ICV|rcsb pdb:5ICW|ensembl:ENST00000407558(transcript)|ensembl:ENST00000414063(transcript)|ensembl:ENST00000572169(transcript)|ensembl:ENST00000572584(transcript)|ensembl:ENST00000575076(transcript)|ensembl:ENST00000649205(transcript)|ensembl:ENST00000649360(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0004402"(histone acetyltransferase activity)|go:"GO:0004596"(peptide alpha-N-acetyltransferase activity)|refseq:NP_001077069.1|refseq:NP_001077070.1|refseq:NP_001304022.1|refseq:NP_001304023.1|refseq:NP_001304024.1|refseq:NP_001304025.1|refseq:NP_001304026.1|refseq:NP_001304027.1|refseq:NP_079121.1|dip:DIP-62077N	refseq:NP_001153656.1|refseq:NP_115505.2|ensembl:ENSG00000187583(gene)|ensembl:ENST00000379410(transcript)|go:"GO:0001666"(response to hypoxia)|go:"GO:0001786"(phosphatidylserine binding)|go:"GO:0005739"(mitochondrion)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005886"(plasma membrane)|go:"GO:0031966"(mitochondrial membrane)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0061158"(3'-UTR-mediated mRNA destabilization)|go:"GO:0070300"(phosphatidic acid binding)|go:"GO:1901612"(cardiolipin binding)|go:"GO:1901981"(phosphatidylinositol phosphate binding)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR037839|interpro:IPR042835|ensembl:ENST00000379407|ensembl:ENSP00000368717|ensembl:ENST00000379409|ensembl:ENSP00000368719|ensembl:ENSP00000368720	-	-	-	figure legend:SF7|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2020/09/28	2020/09/28	rogid:h6UZBaiJehWPTJlM2hiMjxu1zxU9606	rogid:TB3sgI04Vl/d2WNLkD7OPwSjCqQ9606	rigid:KVB94kfdNp77VaHoLKKoCJXwk3w	false	glutathione s tranferase tag:c-c	fluorescent protein tag:c-c	-	-	psi-mi:"MI:0867"(tag visualisation by fluorescence)	psi-mi:"MI:0867"(tag visualisation by fluorescence)
uniprotkb:Q96P09	uniprotkb:Q494U1	intact:EBI-2341055|uniprotkb:Q96RW5|uniprotkb:Q6IPY1	intact:EBI-10241513|uniprotkb:Q5SV98|uniprotkb:Q9H0M7|uniprotkb:Q494U2|ensembl:ENSP00000368720	psi-mi:birc8_human(display_long)|uniprotkb:BIRC8(gene name)|psi-mi:BIRC8(display_short)|uniprotkb:ILP2(gene name synonym)|uniprotkb:Inhibitor of apoptosis-like protein 2(gene name synonym)|uniprotkb:Testis-specific inhibitor of apoptosis(gene name synonym)	psi-mi:pkhn1_human(display_long)|uniprotkb:PLEKHN1(gene name)|psi-mi:PLEKHN1(display_short)|uniprotkb:CLPABP(gene name synonym)|uniprotkb:Cardiolipin and phosphatidic acid-binding protein(gene name synonym)	psi-mi:"MI:0089"(protein array)	Yu et al. (2018)	imex:IM-28385|pubmed:29433439	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26361201|imex:IM-28385-19	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	interpro:IPR042579|refseq:NP_203127.3|interpro:IPR001370(Proteinase inhibitor I32, inhibitor of apoptosis)|interpro:IPR001841(Zinc finger, RING-type)|rcsb pdb:1XB0|rcsb pdb:1XB1|interpro:IPR011029(DEATH-like)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005876"(spindle microtubule)|go:"GO:0031398"(positive regulation of protein ubiquitination)|go:"GO:0043027"(cysteine-type endopeptidase inhibitor activity involved in apoptotic process)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0046872"(metal ion binding)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0090263"(positive regulation of canonical Wnt signaling pathway)	refseq:NP_001153656.1|refseq:NP_115505.2|ensembl:ENSG00000187583(gene)|ensembl:ENST00000379410(transcript)|go:"GO:0001666"(response to hypoxia)|go:"GO:0001786"(phosphatidylserine binding)|go:"GO:0005739"(mitochondrion)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005886"(plasma membrane)|go:"GO:0031966"(mitochondrial membrane)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0061158"(3'-UTR-mediated mRNA destabilization)|go:"GO:0070300"(phosphatidic acid binding)|go:"GO:1901612"(cardiolipin binding)|go:"GO:1901981"(phosphatidylinositol phosphate binding)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR037839|interpro:IPR042835|ensembl:ENST00000379407|ensembl:ENSP00000368717|ensembl:ENST00000379409|ensembl:ENSP00000368719|ensembl:ENSP00000368720	-	-	-	figure legend:SF7|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2020/09/28	2020/09/28	rogid:dNa54zbu4SMSRJ8FXGBLuqGJ0qo9606	rogid:TB3sgI04Vl/d2WNLkD7OPwSjCqQ9606	rigid:sfxPhT4a86nOQGGlm059FIuU//o	false	glutathione s tranferase tag:c-c	fluorescent protein tag:c-c	-	-	psi-mi:"MI:0867"(tag visualisation by fluorescence)	psi-mi:"MI:0867"(tag visualisation by fluorescence)
uniprotkb:Q13488	uniprotkb:Q494U1	intact:EBI-3914669|uniprotkb:Q8WVC5|uniprotkb:O75877|ensembl:ENSP00000265686	intact:EBI-10241513|uniprotkb:Q5SV98|uniprotkb:Q9H0M7|uniprotkb:Q494U2|ensembl:ENSP00000368720	psi-mi:vpp3_human(display_long)|uniprotkb:TCIRG1(gene name)|psi-mi:TCIRG1(display_short)|uniprotkb:ATP6N1C(gene name synonym)|uniprotkb:ATP6V0A3(gene name synonym)|uniprotkb:Osteoclastic proton pump 116 kDa subunit(gene name synonym)|uniprotkb:T-cell immune regulator 1(gene name synonym)|uniprotkb:T-cell immune response cDNA7 protein(gene name synonym)|uniprotkb:Vacuolar proton translocating ATPase 116 kDa subunit a isoform 3(gene name synonym)	psi-mi:pkhn1_human(display_long)|uniprotkb:PLEKHN1(gene name)|psi-mi:PLEKHN1(display_short)|uniprotkb:CLPABP(gene name synonym)|uniprotkb:Cardiolipin and phosphatidic acid-binding protein(gene name synonym)	psi-mi:"MI:0089"(protein array)	Yu et al. (2018)	imex:IM-28385|pubmed:29433439	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26361209|imex:IM-28385-51	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:XP_011543028.1|refseq:NP_006010.2|refseq:NP_006044.1|ensembl:ENSG00000110719(gene)|ensembl:ENST00000265686(transcript)|go:"GO:0000045"(autophagosome assembly)|go:"GO:0000220"(vacuolar proton-transporting V-type ATPase, V0 domain)|go:"GO:0001503"(ossification)|go:"GO:0002158"(osteoclast proliferation)|go:"GO:0005215"(transporter activity)|go:"GO:0005634"(nucleus)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005770"(late endosome)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006874"(cellular calcium ion homeostasis)|go:"GO:0006915"(apoptotic process)|go:"GO:0006954"(inflammatory response)|go:"GO:0006968"(cellular defense response)|go:"GO:0007035"(vacuolar acidification)|go:"GO:0007039"(protein catabolic process in the vacuole)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0010008"(endosome membrane)|go:"GO:0010155"(regulation of proton transport)|go:"GO:0010272"(response to silver ion)|go:"GO:0010467"(gene expression)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0016064"(immunoglobulin mediated immune response)|go:"GO:0016236"(macroautophagy)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0016471"(vacuolar proton-transporting V-type ATPase complex)|go:"GO:0021554"(optic nerve development)|go:"GO:0030010"(establishment of cell polarity)|go:"GO:0030183"(B cell differentiation)|go:"GO:0030217"(T cell differentiation)|go:"GO:0030316"(osteoclast differentiation)|go:"GO:0030670"(phagocytic vesicle membrane)|go:"GO:0031529"(ruffle organization)|go:"GO:0033365"(protein localization to organelle)|go:"GO:0035709"(memory T cell activation)|go:"GO:0035711"(T-helper 1 cell activation)|go:"GO:0043029"(T cell homeostasis)|go:"GO:0044691"(tooth eruption)|go:"GO:0045453"(bone resorption)|go:"GO:0045667"(regulation of osteoblast differentiation)|go:"GO:0046961"(proton-transporting ATPase activity, rotational mechanism)|go:"GO:0050796"(regulation of insulin secretion)|go:"GO:0051117"(ATPase binding)|go:"GO:0051650"(establishment of vesicle localization)|go:"GO:0060041"(retina development in camera-type eye)|go:"GO:0061484"(hematopoietic stem cell homeostasis)|go:"GO:0070166"(enamel mineralization)|go:"GO:0071345"(cellular response to cytokine stimulus)|go:"GO:0090383"(phagosome acidification)|go:"GO:0097188"(dentin mineralization)|go:"GO:0101003"(ficolin-1-rich granule membrane)|go:"GO:1902600"(proton transmembrane transport)|interpro:IPR002490(ATPase, V0/A0 complex, 116-kDa subunit)|interpro:IPR026028|reactome:R-HSA-1222556|reactome:R-HSA-6798695|reactome:R-HSA-77387|reactome:R-HSA-917977|reactome:R-HSA-9639288|reactome:R-HSA-983712|refseq:XP_005273766.1	refseq:NP_001153656.1|refseq:NP_115505.2|ensembl:ENSG00000187583(gene)|ensembl:ENST00000379410(transcript)|go:"GO:0001666"(response to hypoxia)|go:"GO:0001786"(phosphatidylserine binding)|go:"GO:0005739"(mitochondrion)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005886"(plasma membrane)|go:"GO:0031966"(mitochondrial membrane)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0061158"(3'-UTR-mediated mRNA destabilization)|go:"GO:0070300"(phosphatidic acid binding)|go:"GO:1901612"(cardiolipin binding)|go:"GO:1901981"(phosphatidylinositol phosphate binding)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR037839|interpro:IPR042835|ensembl:ENST00000379407|ensembl:ENSP00000368717|ensembl:ENST00000379409|ensembl:ENSP00000368719|ensembl:ENSP00000368720	-	-	-	figure legend:SF7|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2020/09/28	2020/09/28	rogid:WhJvt8AOkbC24bz4x4CxGyZcuow9606	rogid:TB3sgI04Vl/d2WNLkD7OPwSjCqQ9606	rigid:g381vZVWY3eZ+1d2vuj96Sqeqt4	false	glutathione s tranferase tag:c-c	fluorescent protein tag:c-c	-	-	psi-mi:"MI:0867"(tag visualisation by fluorescence)	psi-mi:"MI:0867"(tag visualisation by fluorescence)
uniprotkb:Q9Y6K9	uniprotkb:Q494U1	intact:EBI-81279|intact:EBI-356130|uniprotkb:Q7LBY6|uniprotkb:Q7Z7F1|ensembl:ENSP00000471166|ensembl:ENSP00000479662	intact:EBI-10241513|uniprotkb:Q5SV98|uniprotkb:Q9H0M7|uniprotkb:Q494U2|ensembl:ENSP00000368720	psi-mi:nemo_human(display_long)|uniprotkb:IKBKG(gene name)|psi-mi:IKBKG(display_short)|uniprotkb:FIP3(gene name synonym)|uniprotkb:NEMO(gene name synonym)|uniprotkb:NF-kappa-B essential modifier(gene name synonym)|uniprotkb:Inhibitor of nuclear factor kappa-B kinase subunit gamma(gene name synonym)|uniprotkb:IkB kinase-associated protein 1(gene name synonym)|uniprotkb:FIP-3(gene name synonym)	psi-mi:pkhn1_human(display_long)|uniprotkb:PLEKHN1(gene name)|psi-mi:PLEKHN1(display_short)|uniprotkb:CLPABP(gene name synonym)|uniprotkb:Cardiolipin and phosphatidic acid-binding protein(gene name synonym)	psi-mi:"MI:0089"(protein array)	Yu et al. (2018)	imex:IM-28385|pubmed:29433439	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26361217|imex:IM-28385-37	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001308325.1|refseq:NP_001308326.1|refseq:NP_001093326.2|refseq:NP_001093327.1|refseq:NP_001138727.1|refseq:NP_003630.1|dip:DIP-27528N|ensembl:ENSG00000269335(gene)|ensembl:ENST00000594239(transcript)|ensembl:ENST00000611071(transcript)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0000922"(spindle pole)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006915"(apoptotic process)|go:"GO:0006954"(inflammatory response)|go:"GO:0006955"(immune response)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0007249"(I-kappaB kinase/NF-kappaB signaling)|go:"GO:0008385"(IkappaB kinase complex)|go:"GO:0009615"(response to virus)|go:"GO:0016239"(positive regulation of macroautophagy)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0042975"(peroxisome proliferator activated receptor binding)|go:"GO:0043122"(regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043276"(anoikis)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045087"(innate immune response)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0050852"(T cell receptor signaling pathway)|go:"GO:0050862"(positive regulation of T cell receptor signaling pathway)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|go:"GO:0051650"(establishment of vesicle localization)|go:"GO:0065003"(protein-containing complex assembly)|go:"GO:0070530"(K63-linked polyubiquitin modification-dependent protein binding)|go:"GO:0072686"(mitotic spindle)|go:"GO:1901215"(negative regulation of neuron death)|go:"GO:1990450"(linear polyubiquitin binding)|go:"GO:1990459"(transferrin receptor binding)|interpro:IPR021063|interpro:IPR032419|interpro:IPR034735|mint:Q9Y6K9|rcsb pdb:2JVX|rcsb pdb:2JVY|rcsb pdb:3BRT|rcsb pdb:3BRV|rcsb pdb:3CL3|rcsb pdb:3FX0|rcsb pdb:4BWN|rcsb pdb:5AAY|rcsb pdb:5LDE|rcsb pdb:6MI3|rcsb pdb:6MI4|rcsb pdb:6YEK|reactome:R-HSA-1169091|reactome:R-HSA-1236974|reactome:R-HSA-168638|reactome:R-HSA-168927|reactome:R-HSA-1810476|reactome:R-HSA-202424|reactome:R-HSA-2871837|reactome:R-HSA-445989|reactome:R-HSA-450302|reactome:R-HSA-450321|reactome:R-HSA-4755510|reactome:R-HSA-5357905|reactome:R-HSA-5357956|reactome:R-HSA-5602636|reactome:R-HSA-5603027|reactome:R-HSA-5603029|reactome:R-HSA-5607764|reactome:R-HSA-5684264|reactome:R-HSA-5689880|reactome:R-HSA-5689896|reactome:R-HSA-9020702|reactome:R-HSA-933542|reactome:R-HSA-933543|reactome:R-HSA-937039|reactome:R-HSA-937041|reactome:R-HSA-975144	refseq:NP_001153656.1|refseq:NP_115505.2|ensembl:ENSG00000187583(gene)|ensembl:ENST00000379410(transcript)|go:"GO:0001666"(response to hypoxia)|go:"GO:0001786"(phosphatidylserine binding)|go:"GO:0005739"(mitochondrion)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005886"(plasma membrane)|go:"GO:0031966"(mitochondrial membrane)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0061158"(3'-UTR-mediated mRNA destabilization)|go:"GO:0070300"(phosphatidic acid binding)|go:"GO:1901612"(cardiolipin binding)|go:"GO:1901981"(phosphatidylinositol phosphate binding)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR037839|interpro:IPR042835|ensembl:ENST00000379407|ensembl:ENSP00000368717|ensembl:ENST00000379409|ensembl:ENSP00000368719|ensembl:ENSP00000368720	-	-	-	figure legend:SF7|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2020/09/28	2020/09/28	rogid:9OeZIMeJvNtDEMoiLaKwVEpxSSM9606	rogid:TB3sgI04Vl/d2WNLkD7OPwSjCqQ9606	rigid:gBRFcMow6RYJgvnUVfWuuaDhiq0	false	glutathione s tranferase tag:c-c	fluorescent protein tag:c-c	-	-	psi-mi:"MI:0867"(tag visualisation by fluorescence)	psi-mi:"MI:0867"(tag visualisation by fluorescence)
uniprotkb:P28074	uniprotkb:Q494U1	intact:EBI-357828|uniprotkb:Q16242|uniprotkb:Q6PEW2|intact:EBI-1237472|uniprotkb:Q7Z3B5|uniprotkb:Q9TNN9|uniprotkb:B2R4N9|uniprotkb:D3DS43|uniprotkb:B4DUM9|uniprotkb:Q86T01|uniprotkb:E9PAV2|ensembl:ENSP00000355325	intact:EBI-10241513|uniprotkb:Q5SV98|uniprotkb:Q9H0M7|uniprotkb:Q494U2|ensembl:ENSP00000368720	psi-mi:psb5_human(display_long)|uniprotkb:PSMB5(gene name)|psi-mi:PSMB5(display_short)|uniprotkb:LMPX(gene name synonym)|uniprotkb:Proteasome epsilon chain(gene name synonym)|uniprotkb:Macropain epsilon chain(gene name synonym)|uniprotkb:Multicatalytic endopeptidase complex epsilon chain(gene name synonym)|uniprotkb:Proteasome subunit X(gene name synonym)|uniprotkb:Proteasome chain 6(gene name synonym)|uniprotkb:Proteasome subunit MB1(gene name synonym)|uniprotkb:MB1(gene name synonym)|uniprotkb:X(gene name synonym)	psi-mi:pkhn1_human(display_long)|uniprotkb:PLEKHN1(gene name)|psi-mi:PLEKHN1(display_short)|uniprotkb:CLPABP(gene name synonym)|uniprotkb:Cardiolipin and phosphatidic acid-binding protein(gene name synonym)	psi-mi:"MI:0089"(protein array)	Yu et al. (2018)	imex:IM-28385|pubmed:29433439	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26361231|imex:IM-28385-39	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001124197.1|refseq:NP_001138404.1|refseq:NP_002788.1|dip:DIP-27540N|reactome:R-HSA-187577|reactome:R-HSA-195253|reactome:R-HSA-202424|reactome:R-HSA-211733|reactome:R-HSA-2467813|reactome:R-HSA-2871837|reactome:R-HSA-349425|reactome:R-HSA-350562|reactome:R-HSA-382556|reactome:R-HSA-450408|reactome:R-HSA-4608870|reactome:R-HSA-4641257|reactome:R-HSA-4641258|reactome:R-HSA-5358346|reactome:R-HSA-5362768|reactome:R-HSA-5607761|reactome:R-HSA-5607764|reactome:R-HSA-5610780|reactome:R-HSA-5610783|reactome:R-HSA-5632684|reactome:R-HSA-5658442|reactome:R-HSA-5668541|reactome:R-HSA-5676590|reactome:R-HSA-5678895|reactome:R-HSA-5687128|reactome:R-HSA-5689603|reactome:R-HSA-5689880|reactome:R-HSA-68827|reactome:R-HSA-68949|reactome:R-HSA-69017|reactome:R-HSA-69481|reactome:R-HSA-69601|reactome:R-HSA-75815|reactome:R-HSA-8852276|reactome:R-HSA-8854050|reactome:R-HSA-8932339|reactome:R-HSA-8939236|reactome:R-HSA-8939902|reactome:R-HSA-8941858|reactome:R-HSA-8948751|reactome:R-HSA-8951664|reactome:R-HSA-9010553|reactome:R-HSA-9020702|reactome:R-HSA-9604323|reactome:R-HSA-983168|reactome:R-HSA-5610785|rcsb pdb:6KWY|rcsb pdb:6MSB|rcsb pdb:6MSD|rcsb pdb:6MSE|rcsb pdb:6MSG|rcsb pdb:6MSH|rcsb pdb:6MSJ|rcsb pdb:6MSK|rcsb pdb:6R70|rcsb pdb:6REY|rcsb pdb:6RGQ|rcsb pdb:6WJD|rcsb pdb:6WJN|rcsb pdb:6XMJ|reactome:R-HSA-1169091|reactome:R-HSA-1234176|reactome:R-HSA-1236974|reactome:R-HSA-1236978|reactome:R-HSA-174084|reactome:R-HSA-174113|reactome:R-HSA-174154|reactome:R-HSA-174178|reactome:R-HSA-174184|reactome:R-HSA-180534|reactome:R-HSA-180585|ensembl:ENSG00000100804(gene)|ensembl:ENST00000361611(transcript)|go:"GO:0000502"(proteasome complex)|go:"GO:0004175"(endopeptidase activity)|go:"GO:0004298"(threonine-type endopeptidase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005839"(proteasome core complex)|go:"GO:0006508"(proteolysis)|go:"GO:0006979"(response to oxidative stress)|go:"GO:0008233"(peptidase activity)|go:"GO:0010499"(proteasomal ubiquitin-independent protein catabolic process)|go:"GO:0019774"(proteasome core complex, beta-subunit complex)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0070062"(extracellular exosome)|interpro:IPR000243(Peptidase T1A, proteasome beta-subunit)|interpro:IPR001353(20S proteasome, A and B subunits)|interpro:IPR016050(Proteasome, beta-type subunit, conserved site)|interpro:IPR023333|interpro:IPR029055|interpro:IPR037558|mint:P28074|rcsb pdb:4R3O|rcsb pdb:4R67|rcsb pdb:5A0Q|rcsb pdb:5GJQ|rcsb pdb:5GJR|rcsb pdb:5L4G|rcsb pdb:5L5W|rcsb pdb:5L5X|rcsb pdb:5L5Y|rcsb pdb:5L5Z|rcsb pdb:5L60|rcsb pdb:5L61|rcsb pdb:5L62|rcsb pdb:5L63|rcsb pdb:5L64|rcsb pdb:5LE5|rcsb pdb:5LEX|rcsb pdb:5LEY|rcsb pdb:5LEZ|rcsb pdb:5LF0|rcsb pdb:5LF1|rcsb pdb:5LF3|rcsb pdb:5LF4|rcsb pdb:5LF6|rcsb pdb:5LF7|rcsb pdb:5LN3|rcsb pdb:5M32|rcsb pdb:5T0C|rcsb pdb:5T0G|rcsb pdb:5T0H|rcsb pdb:5T0I|rcsb pdb:5T0J|rcsb pdb:5VFO|rcsb pdb:5VFP|rcsb pdb:5VFQ|rcsb pdb:5VFR|rcsb pdb:5VFS|rcsb pdb:5VFT|rcsb pdb:5VFU	refseq:NP_001153656.1|refseq:NP_115505.2|ensembl:ENSG00000187583(gene)|ensembl:ENST00000379410(transcript)|go:"GO:0001666"(response to hypoxia)|go:"GO:0001786"(phosphatidylserine binding)|go:"GO:0005739"(mitochondrion)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005886"(plasma membrane)|go:"GO:0031966"(mitochondrial membrane)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0061158"(3'-UTR-mediated mRNA destabilization)|go:"GO:0070300"(phosphatidic acid binding)|go:"GO:1901612"(cardiolipin binding)|go:"GO:1901981"(phosphatidylinositol phosphate binding)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR037839|interpro:IPR042835|ensembl:ENST00000379407|ensembl:ENSP00000368717|ensembl:ENST00000379409|ensembl:ENSP00000368719|ensembl:ENSP00000368720	-	-	-	figure legend:SF7|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2020/09/28	2020/09/28	rogid:73T59wniLri/465F3BhBvwL1/LM9606	rogid:TB3sgI04Vl/d2WNLkD7OPwSjCqQ9606	rigid:HT31i7J63Vn9yGu4n9Qptw8LKVM	false	glutathione s tranferase tag:c-c	fluorescent protein tag:c-c	-	-	psi-mi:"MI:0867"(tag visualisation by fluorescence)	psi-mi:"MI:0867"(tag visualisation by fluorescence)
uniprotkb:Q494U1	uniprotkb:Q5ZWZ3	intact:EBI-10241513|uniprotkb:Q5SV98|uniprotkb:Q9H0M7|uniprotkb:Q494U2|ensembl:ENSP00000368720	intact:EBI-6417967|ensemblbacteria:AAU27027	psi-mi:pkhn1_human(display_long)|uniprotkb:PLEKHN1(gene name)|psi-mi:PLEKHN1(display_short)|uniprotkb:CLPABP(gene name synonym)|uniprotkb:Cardiolipin and phosphatidic acid-binding protein(gene name synonym)	psi-mi:q5zwz3_legph(display_long)|uniprotkb:lpg0940(locus name)	psi-mi:"MI:0089"(protein array)	Yu et al. (2018)	imex:IM-28385|pubmed:29433439	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:272624(legph)|taxid:272624(Legionella pneumophila subsp. pneumophila)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26361239|imex:IM-28385-53	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001153656.1|refseq:NP_115505.2|ensembl:ENSG00000187583(gene)|ensembl:ENST00000379410(transcript)|go:"GO:0001666"(response to hypoxia)|go:"GO:0001786"(phosphatidylserine binding)|go:"GO:0005739"(mitochondrion)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005886"(plasma membrane)|go:"GO:0031966"(mitochondrial membrane)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0061158"(3'-UTR-mediated mRNA destabilization)|go:"GO:0070300"(phosphatidic acid binding)|go:"GO:1901612"(cardiolipin binding)|go:"GO:1901981"(phosphatidylinositol phosphate binding)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR037839|interpro:IPR042835|ensembl:ENST00000379407|ensembl:ENSP00000368717|ensembl:ENST00000379409|ensembl:ENSP00000368719|ensembl:ENSP00000368720	ensemblbacteria:AAU27027(transcript)|ensemblbacteria:lpg0940(gene)|interpro:IPR041463|rcsb pdb:3TNF|refseq:YP_094974.1|refseq:WP_010946675.1|dip:DIP-59799N	-	-	-	figure legend:SF7|comment:Positive control|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2020/09/28	2020/09/28	rogid:TB3sgI04Vl/d2WNLkD7OPwSjCqQ9606	rogid:AyBH7iPqbJYlEKGIubXHtBV/M+U272624	rigid:vBRez76pwvRXUdBfCMRqcGGFEao	false	fluorescent protein tag:c-c	glutathione s tranferase tag:c-c	-	-	psi-mi:"MI:0867"(tag visualisation by fluorescence)	psi-mi:"MI:0867"(tag visualisation by fluorescence)
uniprotkb:Q15286	uniprotkb:Q494U1	intact:EBI-722275|uniprotkb:B4E390|uniprotkb:B2R6E0|ensembl:ENSP00000229340	intact:EBI-10241513|uniprotkb:Q5SV98|uniprotkb:Q9H0M7|uniprotkb:Q494U2|ensembl:ENSP00000368720	psi-mi:rab35_human(display_long)|uniprotkb:Ras-related protein Rab-1C(gene name synonym)|uniprotkb:GTP-binding protein RAY(gene name synonym)|uniprotkb:RAB35(gene name)|psi-mi:RAB35(display_short)|uniprotkb:RAB1C(gene name synonym)|uniprotkb:RAY(gene name synonym)	psi-mi:pkhn1_human(display_long)|uniprotkb:PLEKHN1(gene name)|psi-mi:PLEKHN1(display_short)|uniprotkb:CLPABP(gene name synonym)|uniprotkb:Cardiolipin and phosphatidic acid-binding protein(gene name synonym)	psi-mi:"MI:0089"(protein array)	Yu et al. (2018)	imex:IM-28385|pubmed:29433439	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26361247|imex:IM-28385-55	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001161078.1|refseq:NP_006852.1|ensembl:ENSG00000111737(gene)|ensembl:ENST00000229340(transcript)|go:"GO:0000281"(mitotic cytokinesis)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005546"(phosphatidylinositol-4,5-bisphosphate binding)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005905"(clathrin-coated pit)|go:"GO:0008104"(protein localization)|go:"GO:0010008"(endosome membrane)|go:"GO:0015031"(protein transport)|go:"GO:0016197"(endosomal transport)|go:"GO:0019003"(GDP binding)|go:"GO:0019882"(antigen processing and presentation)|go:"GO:0030669"(clathrin-coated endocytic vesicle membrane)|go:"GO:0031175"(neuron projection development)|go:"GO:0031253"(cell projection membrane)|go:"GO:0032456"(endocytic recycling)|go:"GO:0032482"(Rab protein signal transduction)|go:"GO:0036010"(protein localization to endosome)|go:"GO:0042470"(melanosome)|go:"GO:0045171"(intercellular bridge)|go:"GO:0045334"(clathrin-coated endocytic vesicle)|go:"GO:0048227"(plasma membrane to endosome transport)|go:"GO:0055038"(recycling endosome membrane)|go:"GO:0070062"(extracellular exosome)|go:"GO:0098993"(anchored component of synaptic vesicle membrane)|go:"GO:1990090"(cellular response to nerve growth factor stimulus)|interpro:IPR001806(Ras GTPase)|interpro:IPR005225(Small GTP-binding protein)|interpro:IPR027417|interpro:IPR041815|mint:Q15286|rcsb pdb:3TW8|rcsb pdb:6EKK|rcsb pdb:6IF2|rcsb pdb:6IF3|reactome:R-HSA-8854214|reactome:R-HSA-8873719|reactome:R-HSA-8876198	refseq:NP_001153656.1|refseq:NP_115505.2|ensembl:ENSG00000187583(gene)|ensembl:ENST00000379410(transcript)|go:"GO:0001666"(response to hypoxia)|go:"GO:0001786"(phosphatidylserine binding)|go:"GO:0005739"(mitochondrion)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005886"(plasma membrane)|go:"GO:0031966"(mitochondrial membrane)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0061158"(3'-UTR-mediated mRNA destabilization)|go:"GO:0070300"(phosphatidic acid binding)|go:"GO:1901612"(cardiolipin binding)|go:"GO:1901981"(phosphatidylinositol phosphate binding)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR037839|interpro:IPR042835|ensembl:ENST00000379407|ensembl:ENSP00000368717|ensembl:ENST00000379409|ensembl:ENSP00000368719|ensembl:ENSP00000368720	-	-	-	figure legend:SF7|comment:Positive control|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2020/09/28	2020/09/28	rogid:95pH+DyDjv9FcxFeMmGYoJ0KyPo9606	rogid:TB3sgI04Vl/d2WNLkD7OPwSjCqQ9606	rigid:fYtTMiUdRor0TaoianvmzUpwmuY	false	glutathione s tranferase tag:c-c	fluorescent protein tag:c-c	-	-	psi-mi:"MI:0867"(tag visualisation by fluorescence)	psi-mi:"MI:0867"(tag visualisation by fluorescence)
uniprotkb:Q494U1	uniprotkb:Q5ZXN6	intact:EBI-10241513|uniprotkb:Q5SV98|uniprotkb:Q9H0M7|uniprotkb:Q494U2|ensembl:ENSP00000368720	intact:EBI-26359852|ensemblbacteria:AAU26784	psi-mi:pkhn1_human(display_long)|uniprotkb:PLEKHN1(gene name)|psi-mi:PLEKHN1(display_short)|uniprotkb:CLPABP(gene name synonym)|uniprotkb:Cardiolipin and phosphatidic acid-binding protein(gene name synonym)	psi-mi:ankx_legph(display_long)|uniprotkb:ankX(gene name)|psi-mi:ankX(display_short)|uniprotkb:legA8(gene name synonym)|uniprotkb:lpg0695(locus name)|uniprotkb:Ankyrin repeat-containing protein X(gene name synonym)	psi-mi:"MI:0096"(pull down)	Yu et al. (2018)	imex:IM-28385|pubmed:29433439	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:272624(legph)|taxid:272624(Legionella pneumophila subsp. pneumophila)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26360575|imex:IM-28385-7	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001153656.1|refseq:NP_115505.2|ensembl:ENSG00000187583(gene)|ensembl:ENST00000379410(transcript)|go:"GO:0001666"(response to hypoxia)|go:"GO:0001786"(phosphatidylserine binding)|go:"GO:0005739"(mitochondrion)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005886"(plasma membrane)|go:"GO:0031966"(mitochondrial membrane)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0061158"(3'-UTR-mediated mRNA destabilization)|go:"GO:0070300"(phosphatidic acid binding)|go:"GO:1901612"(cardiolipin binding)|go:"GO:1901981"(phosphatidylinositol phosphate binding)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR037839|interpro:IPR042835|ensembl:ENST00000379407|ensembl:ENSP00000368717|ensembl:ENST00000379409|ensembl:ENSP00000368719|ensembl:ENSP00000368720	ensemblbacteria:AAU26784(transcript)|ensemblbacteria:lpg0695(gene)|go:"GO:0005576"(extracellular region)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0043087"(regulation of GTPase activity)|go:"GO:0044605"(phosphocholine transferase activity)|rcsb pdb:6SKU|refseq:YP_094731.1|rcsb pdb:4BEP|rcsb pdb:4BER|rcsb pdb:4BES|rcsb pdb:4BET|interpro:IPR002110(Ankyrin)|interpro:IPR020683|interpro:IPR036770|interpro:IPR003812(Filamentation induced by cAMP protein Fic)|interpro:IPR036597	-	-	-	figure legend:f2a f2b|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2020/09/28	2020/09/28	rogid:TB3sgI04Vl/d2WNLkD7OPwSjCqQ9606	rogid:97DncqzHYB0l66zqkQj9On5h/nU272624	rigid:1uxx4uEPyNwYJcw3/83CAxKXY/E	false	glutathione s tranferase tag:n-n	fluorescent protein tag:c-c	-	-	psi-mi:"MI:0867"(tag visualisation by fluorescence)	psi-mi:"MI:0867"(tag visualisation by fluorescence)
uniprotkb:Q86WP2	uniprotkb:Q5ZXN6	intact:EBI-2349758|uniprotkb:A6NKW3|uniprotkb:Q6NSH6|uniprotkb:Q9H785|uniprotkb:Q9H0D4|uniprotkb:Q9NSN4|intact:EBI-28972285|ensembl:ENSP00000421202	intact:EBI-26359852|ensemblbacteria:AAU26784	psi-mi:gpbp1_human(display_long)|uniprotkb:GPBP1(gene name)|psi-mi:GPBP1(display_short)|uniprotkb:GPBP(gene name synonym)|uniprotkb:SSH6(gene name synonym)|uniprotkb:GC-rich promoter-binding protein 1(gene name synonym)|uniprotkb:Vascular wall-linked protein(gene name synonym)	psi-mi:ankx_legph(display_long)|uniprotkb:ankX(gene name)|psi-mi:ankX(display_short)|uniprotkb:legA8(gene name synonym)|uniprotkb:lpg0695(locus name)|uniprotkb:Ankyrin repeat-containing protein X(gene name synonym)	psi-mi:"MI:0096"(pull down)	Yu et al. (2018)	imex:IM-28385|pubmed:29433439	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:272624(legph)|taxid:272624(Legionella pneumophila subsp. pneumophila)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26360608|imex:IM-28385-9	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENST00000264779|ensembl:ENSP00000264779|ensembl:ENSP00000421202|ensembl:ENST00000511209|ensembl:ENSP00000422337|ensembl:ENST00000514387|ensembl:ENSP00000421709|refseq:NP_001120707.2|refseq:NP_001120708.1|refseq:NP_001190175.1|refseq:NP_075064.1|refseq:XP_016865245.1|refseq:XP_016865246.1|refseq:XP_016865247.1|refseq:XP_016865248.1|ensembl:ENSG00000062194(gene)|ensembl:ENST00000506184(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|interpro:IPR028128|mint:Q86WP2	ensemblbacteria:AAU26784(transcript)|ensemblbacteria:lpg0695(gene)|go:"GO:0005576"(extracellular region)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0043087"(regulation of GTPase activity)|go:"GO:0044605"(phosphocholine transferase activity)|rcsb pdb:6SKU|refseq:YP_094731.1|rcsb pdb:4BEP|rcsb pdb:4BER|rcsb pdb:4BES|rcsb pdb:4BET|interpro:IPR002110(Ankyrin)|interpro:IPR020683|interpro:IPR036770|interpro:IPR003812(Filamentation induced by cAMP protein Fic)|interpro:IPR036597	-	-	-	figure legend:f2a f2b|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2020/09/28	2020/09/28	rogid:YpnFRXC1FDOxqNl2Dq67tJRNO6o9606	rogid:97DncqzHYB0l66zqkQj9On5h/nU272624	rigid:yoCB7W4qY4K+QGhpLysXJUQnOYo	false	glutathione s tranferase tag:n-n	fluorescent protein tag:c-c	-	-	psi-mi:"MI:0867"(tag visualisation by fluorescence)	psi-mi:"MI:0867"(tag visualisation by fluorescence)
uniprotkb:Q8TBK6	uniprotkb:Q5ZXN6	intact:EBI-597063|uniprotkb:Q9NXR4|ensembl:ENSP00000423276	intact:EBI-26359852|ensemblbacteria:AAU26784	psi-mi:zch10_human(display_long)|uniprotkb:ZCCHC10(gene name)|psi-mi:ZCCHC10(display_short)	psi-mi:ankx_legph(display_long)|uniprotkb:ankX(gene name)|psi-mi:ankX(display_short)|uniprotkb:legA8(gene name synonym)|uniprotkb:lpg0695(locus name)|uniprotkb:Ankyrin repeat-containing protein X(gene name synonym)	psi-mi:"MI:0096"(pull down)	Yu et al. (2018)	imex:IM-28385|pubmed:29433439	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:272624(legph)|taxid:272624(Legionella pneumophila subsp. pneumophila)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26360616|imex:IM-28385-25	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_060135.1|refseq:NP_001287746.1|refseq:NP_001287747.1|refseq:NP_001287748.1|refseq:NP_001287751.1|refseq:NP_001295056.1|refseq:NP_001295057.1|refseq:NP_001295058.1|refseq:NP_001295059.1|refseq:NP_001287745.1|ensembl:ENSG00000155329(gene)|ensembl:ENST00000509437(transcript)|go:"GO:0003676"(nucleic acid binding)|go:"GO:0008270"(zinc ion binding)|interpro:IPR036875|interpro:IPR039715	ensemblbacteria:AAU26784(transcript)|ensemblbacteria:lpg0695(gene)|go:"GO:0005576"(extracellular region)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0043087"(regulation of GTPase activity)|go:"GO:0044605"(phosphocholine transferase activity)|rcsb pdb:6SKU|refseq:YP_094731.1|rcsb pdb:4BEP|rcsb pdb:4BER|rcsb pdb:4BES|rcsb pdb:4BET|interpro:IPR002110(Ankyrin)|interpro:IPR020683|interpro:IPR036770|interpro:IPR003812(Filamentation induced by cAMP protein Fic)|interpro:IPR036597	-	-	-	figure legend:f2a f2b|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2020/09/28	2020/09/28	rogid:WcCfa6tnoaA9NGta4vXKUY3VnxI9606	rogid:97DncqzHYB0l66zqkQj9On5h/nU272624	rigid:cs0Xb4fA7s1jnHDY4jttm7GTZsw	false	glutathione s tranferase tag:n-n	fluorescent protein tag:c-c	-	-	psi-mi:"MI:0867"(tag visualisation by fluorescence)	psi-mi:"MI:0867"(tag visualisation by fluorescence)
uniprotkb:Q8N3F8	uniprotkb:Q5ZXN6	intact:EBI-1056885|uniprotkb:Q5TI16|uniprotkb:Q7RTP5|uniprotkb:Q8N3N8|uniprotkb:Q9BVL9|uniprotkb:Q9BY92|uniprotkb:Q9UH43|uniprotkb:Q9UH44|uniprotkb:Q9UH45|ensembl:ENSP00000215957	intact:EBI-26359852|ensemblbacteria:AAU26784	psi-mi:milk1_human(display_long)|uniprotkb:MICALL1(gene name)|psi-mi:MICALL1(display_short)|uniprotkb:KIAA1668(gene name synonym)|uniprotkb:MIRAB13(gene name synonym)|uniprotkb:Molecule interacting with Rab13(gene name synonym)	psi-mi:ankx_legph(display_long)|uniprotkb:ankX(gene name)|psi-mi:ankX(display_short)|uniprotkb:legA8(gene name synonym)|uniprotkb:lpg0695(locus name)|uniprotkb:Ankyrin repeat-containing protein X(gene name synonym)	psi-mi:"MI:0096"(pull down)	Yu et al. (2018)	imex:IM-28385|pubmed:29433439	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:272624(legph)|taxid:272624(Legionella pneumophila subsp. pneumophila)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26360624|imex:IM-28385-27	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_203744.1|ensembl:ENSP00000215957|ensembl:ENSG00000100139(gene)|ensembl:ENST00000215957(transcript)|go:"GO:0005770"(late endosome)|go:"GO:0006612"(protein targeting to membrane)|go:"GO:0006897"(endocytosis)|go:"GO:0006898"(receptor-mediated endocytosis)|go:"GO:0019898"(extrinsic component of membrane)|go:"GO:0031175"(neuron projection development)|go:"GO:0031267"(small GTPase binding)|go:"GO:0031902"(late endosome membrane)|go:"GO:0032456"(endocytic recycling)|go:"GO:0032458"(slow endocytic recycling)|go:"GO:0036010"(protein localization to endosome)|go:"GO:0042802"(identical protein binding)|go:"GO:0046872"(metal ion binding)|go:"GO:0055038"(recycling endosome membrane)|go:"GO:0070300"(phosphatidic acid binding)|go:"GO:0097320"(plasma membrane tubulation)|go:"GO:1990090"(cellular response to nerve growth factor stimulus)|interpro:IPR001715(Calponin-like actin-binding)|interpro:IPR001781(Zinc finger, LIM-type)|interpro:IPR022735|interpro:IPR028563|interpro:IPR036872|mint:Q8N3F8|rcsb pdb:2KSP|go:"GO:0045296"(cadherin binding)	ensemblbacteria:AAU26784(transcript)|ensemblbacteria:lpg0695(gene)|go:"GO:0005576"(extracellular region)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0043087"(regulation of GTPase activity)|go:"GO:0044605"(phosphocholine transferase activity)|rcsb pdb:6SKU|refseq:YP_094731.1|rcsb pdb:4BEP|rcsb pdb:4BER|rcsb pdb:4BES|rcsb pdb:4BET|interpro:IPR002110(Ankyrin)|interpro:IPR020683|interpro:IPR036770|interpro:IPR003812(Filamentation induced by cAMP protein Fic)|interpro:IPR036597	-	-	-	figure legend:f2a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2020/09/28	2020/09/28	rogid:G64P9EtjEfLIVLYkb+w3vCWaT0w9606	rogid:97DncqzHYB0l66zqkQj9On5h/nU272624	rigid:PdqN5Q9YlDA7F6QLubEzzeNF/0I	false	glutathione s tranferase tag:n-n	fluorescent protein tag:c-c	-	-	psi-mi:"MI:0867"(tag visualisation by fluorescence)	psi-mi:"MI:0867"(tag visualisation by fluorescence)
uniprotkb:Q9H4M7	uniprotkb:Q5ZXN6	intact:EBI-716549|uniprotkb:Q8N4M8|uniprotkb:Q8N658|ensembl:ENSP00000263265	intact:EBI-26359852|ensemblbacteria:AAU26784	psi-mi:pkha4_human(display_long)|uniprotkb:Phosphoinositol 3-phosphate-binding protein 1(gene name synonym)|uniprotkb:PLEKHA4(gene name)|psi-mi:PLEKHA4(display_short)|uniprotkb:PEPP1(gene name synonym)	psi-mi:ankx_legph(display_long)|uniprotkb:ankX(gene name)|psi-mi:ankX(display_short)|uniprotkb:legA8(gene name synonym)|uniprotkb:lpg0695(locus name)|uniprotkb:Ankyrin repeat-containing protein X(gene name synonym)	psi-mi:"MI:0096"(pull down)	Yu et al. (2018)	imex:IM-28385|pubmed:29433439	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:272624(legph)|taxid:272624(Legionella pneumophila subsp. pneumophila)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26360632|imex:IM-28385-29	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001154826.1|refseq:NP_065955.2|ensembl:ENSG00000105559(gene)|ensembl:ENST00000263265(transcript)|go:"GO:0005546"(phosphatidylinositol-4,5-bisphosphate binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0031234"(extrinsic component of cytoplasmic side of plasma membrane)|go:"GO:0032266"(phosphatidylinositol-3-phosphate binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0043325"(phosphatidylinositol-3,4-bisphosphate binding)|go:"GO:0080025"(phosphatidylinositol-3,5-bisphosphate binding)|go:"GO:0090263"(positive regulation of canonical Wnt signaling pathway)|go:"GO:2000096"(positive regulation of Wnt signaling pathway, planar cell polarity pathway)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR040392|rcsb pdb:1UPQ|rcsb pdb:1UPR|reactome:R-HSA-1660499	ensemblbacteria:AAU26784(transcript)|ensemblbacteria:lpg0695(gene)|go:"GO:0005576"(extracellular region)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0043087"(regulation of GTPase activity)|go:"GO:0044605"(phosphocholine transferase activity)|rcsb pdb:6SKU|refseq:YP_094731.1|rcsb pdb:4BEP|rcsb pdb:4BER|rcsb pdb:4BES|rcsb pdb:4BET|interpro:IPR002110(Ankyrin)|interpro:IPR020683|interpro:IPR036770|interpro:IPR003812(Filamentation induced by cAMP protein Fic)|interpro:IPR036597	-	-	-	figure legend:f2a f2b|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2020/09/28	2020/09/28	rogid:gBeBdIcJIF2fJe6r+Ea2gmiKiTQ9606	rogid:97DncqzHYB0l66zqkQj9On5h/nU272624	rigid:4j4JG3yIkSI9dmUv8ce3lOioauU	false	glutathione s tranferase tag:n-n	fluorescent protein tag:c-c	-	-	psi-mi:"MI:0867"(tag visualisation by fluorescence)	psi-mi:"MI:0867"(tag visualisation by fluorescence)
uniprotkb:Q494U1	uniprotkb:Q5ZXN6	intact:EBI-10241513|uniprotkb:Q5SV98|uniprotkb:Q9H0M7|uniprotkb:Q494U2|ensembl:ENSP00000368720	intact:EBI-26359852|ensemblbacteria:AAU26784	psi-mi:pkhn1_human(display_long)|uniprotkb:PLEKHN1(gene name)|psi-mi:PLEKHN1(display_short)|uniprotkb:CLPABP(gene name synonym)|uniprotkb:Cardiolipin and phosphatidic acid-binding protein(gene name synonym)	psi-mi:ankx_legph(display_long)|uniprotkb:ankX(gene name)|psi-mi:ankX(display_short)|uniprotkb:legA8(gene name synonym)|uniprotkb:lpg0695(locus name)|uniprotkb:Ankyrin repeat-containing protein X(gene name synonym)	psi-mi:"MI:0096"(pull down)	Yu et al. (2018)	imex:IM-28385|pubmed:29433439	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:272624(legph)|taxid:272624(Legionella pneumophila subsp. pneumophila)	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0471"(MINT)	intact:EBI-26360640|imex:IM-28385-31	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001153656.1|refseq:NP_115505.2|ensembl:ENSG00000187583(gene)|ensembl:ENST00000379410(transcript)|go:"GO:0001666"(response to hypoxia)|go:"GO:0001786"(phosphatidylserine binding)|go:"GO:0005739"(mitochondrion)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005886"(plasma membrane)|go:"GO:0031966"(mitochondrial membrane)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0061158"(3'-UTR-mediated mRNA destabilization)|go:"GO:0070300"(phosphatidic acid binding)|go:"GO:1901612"(cardiolipin binding)|go:"GO:1901981"(phosphatidylinositol phosphate binding)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR037839|interpro:IPR042835|ensembl:ENST00000379407|ensembl:ENSP00000368717|ensembl:ENST00000379409|ensembl:ENSP00000368719|ensembl:ENSP00000368720	ensemblbacteria:AAU26784(transcript)|ensemblbacteria:lpg0695(gene)|go:"GO:0005576"(extracellular region)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0043087"(regulation of GTPase activity)|go:"GO:0044605"(phosphocholine transferase activity)|rcsb pdb:6SKU|refseq:YP_094731.1|rcsb pdb:4BEP|rcsb pdb:4BER|rcsb pdb:4BES|rcsb pdb:4BET|interpro:IPR002110(Ankyrin)|interpro:IPR020683|interpro:IPR036770|interpro:IPR003812(Filamentation induced by cAMP protein Fic)|interpro:IPR036597	-	-	-	figure legend:f3a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2020/09/28	2020/09/28	rogid:TB3sgI04Vl/d2WNLkD7OPwSjCqQ9606	rogid:97DncqzHYB0l66zqkQj9On5h/nU272624	rigid:1uxx4uEPyNwYJcw3/83CAxKXY/E	false	fluorescent protein tag:n-n	glutathione s tranferase tag:n-n	-	-	psi-mi:"MI:0867"(tag visualisation by fluorescence)	psi-mi:"MI:0867"(tag visualisation by fluorescence)
uniprotkb:Q494U1	uniprotkb:Q5ZXN6	intact:EBI-10241513|uniprotkb:Q5SV98|uniprotkb:Q9H0M7|uniprotkb:Q494U2|ensembl:ENSP00000368720	intact:EBI-26359852|ensemblbacteria:AAU26784	psi-mi:pkhn1_human(display_long)|uniprotkb:PLEKHN1(gene name)|psi-mi:PLEKHN1(display_short)|uniprotkb:CLPABP(gene name synonym)|uniprotkb:Cardiolipin and phosphatidic acid-binding protein(gene name synonym)	psi-mi:ankx_legph(display_long)|uniprotkb:ankX(gene name)|psi-mi:ankX(display_short)|uniprotkb:legA8(gene name synonym)|uniprotkb:lpg0695(locus name)|uniprotkb:Ankyrin repeat-containing protein X(gene name synonym)	psi-mi:"MI:0096"(pull down)	Yu et al. (2018)	imex:IM-28385|pubmed:29433439	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:272624(legph)|taxid:272624(Legionella pneumophila subsp. pneumophila)	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0471"(MINT)	intact:EBI-26360858|imex:IM-28385-33	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001153656.1|refseq:NP_115505.2|ensembl:ENSG00000187583(gene)|ensembl:ENST00000379410(transcript)|go:"GO:0001666"(response to hypoxia)|go:"GO:0001786"(phosphatidylserine binding)|go:"GO:0005739"(mitochondrion)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005886"(plasma membrane)|go:"GO:0031966"(mitochondrial membrane)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0061158"(3'-UTR-mediated mRNA destabilization)|go:"GO:0070300"(phosphatidic acid binding)|go:"GO:1901612"(cardiolipin binding)|go:"GO:1901981"(phosphatidylinositol phosphate binding)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR037839|interpro:IPR042835|ensembl:ENST00000379407|ensembl:ENSP00000368717|ensembl:ENST00000379409|ensembl:ENSP00000368719|ensembl:ENSP00000368720	ensemblbacteria:AAU26784(transcript)|ensemblbacteria:lpg0695(gene)|go:"GO:0005576"(extracellular region)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0043087"(regulation of GTPase activity)|go:"GO:0044605"(phosphocholine transferase activity)|rcsb pdb:6SKU|refseq:YP_094731.1|rcsb pdb:4BEP|rcsb pdb:4BER|rcsb pdb:4BES|rcsb pdb:4BET|interpro:IPR002110(Ankyrin)|interpro:IPR020683|interpro:IPR036770|interpro:IPR003812(Filamentation induced by cAMP protein Fic)|interpro:IPR036597	-	-	-	figure legend:f3b|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2020/09/28	2020/09/28	rogid:TB3sgI04Vl/d2WNLkD7OPwSjCqQ9606	rogid:97DncqzHYB0l66zqkQj9On5h/nU272624	rigid:1uxx4uEPyNwYJcw3/83CAxKXY/E	false	fluorescent protein tag:n-n	glutathione s tranferase tag:n-n	-	-	psi-mi:"MI:0705"(anti tag western blot)	psi-mi:"MI:0705"(anti tag western blot)
uniprotkb:Q494U1	uniprotkb:Q5ZXN6	intact:EBI-10241513|uniprotkb:Q5SV98|uniprotkb:Q9H0M7|uniprotkb:Q494U2|ensembl:ENSP00000368720	intact:EBI-26359852|ensemblbacteria:AAU26784	psi-mi:pkhn1_human(display_long)|uniprotkb:PLEKHN1(gene name)|psi-mi:PLEKHN1(display_short)|uniprotkb:CLPABP(gene name synonym)|uniprotkb:Cardiolipin and phosphatidic acid-binding protein(gene name synonym)	psi-mi:ankx_legph(display_long)|uniprotkb:ankX(gene name)|psi-mi:ankX(display_short)|uniprotkb:legA8(gene name synonym)|uniprotkb:lpg0695(locus name)|uniprotkb:Ankyrin repeat-containing protein X(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Yu et al. (2018)	imex:IM-28385|pubmed:29433439	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:272624(legph)|taxid:272624(Legionella pneumophila subsp. pneumophila)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0471"(MINT)	intact:EBI-26361077|imex:IM-28385-47	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001153656.1|refseq:NP_115505.2|ensembl:ENSG00000187583(gene)|ensembl:ENST00000379410(transcript)|go:"GO:0001666"(response to hypoxia)|go:"GO:0001786"(phosphatidylserine binding)|go:"GO:0005739"(mitochondrion)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005886"(plasma membrane)|go:"GO:0031966"(mitochondrial membrane)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0061158"(3'-UTR-mediated mRNA destabilization)|go:"GO:0070300"(phosphatidic acid binding)|go:"GO:1901612"(cardiolipin binding)|go:"GO:1901981"(phosphatidylinositol phosphate binding)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR037839|interpro:IPR042835|ensembl:ENST00000379407|ensembl:ENSP00000368717|ensembl:ENST00000379409|ensembl:ENSP00000368719|ensembl:ENSP00000368720	ensemblbacteria:AAU26784(transcript)|ensemblbacteria:lpg0695(gene)|go:"GO:0005576"(extracellular region)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0043087"(regulation of GTPase activity)|go:"GO:0044605"(phosphocholine transferase activity)|rcsb pdb:6SKU|refseq:YP_094731.1|rcsb pdb:4BEP|rcsb pdb:4BER|rcsb pdb:4BES|rcsb pdb:4BET|interpro:IPR002110(Ankyrin)|interpro:IPR020683|interpro:IPR036770|interpro:IPR003812(Filamentation induced by cAMP protein Fic)|interpro:IPR036597	-	-	-	figure legend:f3c|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2020/09/28	2021/01/27	rogid:TB3sgI04Vl/d2WNLkD7OPwSjCqQ9606	rogid:97DncqzHYB0l66zqkQj9On5h/nU272624	rigid:1uxx4uEPyNwYJcw3/83CAxKXY/E	false	green fluorescent protein tag:n-n	fluorescent protein tag:c-c	-	-	psi-mi:"MI:0705"(anti tag western blot)	psi-mi:"MI:0705"(anti tag western blot)
uniprotkb:Q494U1	uniprotkb:Q5ZXN6	intact:EBI-10241513|uniprotkb:Q5SV98|uniprotkb:Q9H0M7|uniprotkb:Q494U2|ensembl:ENSP00000368720	intact:EBI-26359852|ensemblbacteria:AAU26784	psi-mi:pkhn1_human(display_long)|uniprotkb:PLEKHN1(gene name)|psi-mi:PLEKHN1(display_short)|uniprotkb:CLPABP(gene name synonym)|uniprotkb:Cardiolipin and phosphatidic acid-binding protein(gene name synonym)	psi-mi:ankx_legph(display_long)|uniprotkb:ankX(gene name)|psi-mi:ankX(display_short)|uniprotkb:legA8(gene name synonym)|uniprotkb:lpg0695(locus name)|uniprotkb:Ankyrin repeat-containing protein X(gene name synonym)	psi-mi:"MI:0416"(fluorescence microscopy)	Yu et al. (2018)	imex:IM-28385|pubmed:29433439	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:272624(legph)|taxid:272624(Legionella pneumophila subsp. pneumophila)	psi-mi:"MI:0403"(colocalization)	psi-mi:"MI:0471"(MINT)	intact:EBI-26361104|imex:IM-28385-11	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001153656.1|refseq:NP_115505.2|ensembl:ENSG00000187583(gene)|ensembl:ENST00000379410(transcript)|go:"GO:0001666"(response to hypoxia)|go:"GO:0001786"(phosphatidylserine binding)|go:"GO:0005739"(mitochondrion)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005886"(plasma membrane)|go:"GO:0031966"(mitochondrial membrane)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0061158"(3'-UTR-mediated mRNA destabilization)|go:"GO:0070300"(phosphatidic acid binding)|go:"GO:1901612"(cardiolipin binding)|go:"GO:1901981"(phosphatidylinositol phosphate binding)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR037839|interpro:IPR042835|ensembl:ENST00000379407|ensembl:ENSP00000368717|ensembl:ENST00000379409|ensembl:ENSP00000368719|ensembl:ENSP00000368720	ensemblbacteria:AAU26784(transcript)|ensemblbacteria:lpg0695(gene)|go:"GO:0005576"(extracellular region)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0043087"(regulation of GTPase activity)|go:"GO:0044605"(phosphocholine transferase activity)|rcsb pdb:6SKU|refseq:YP_094731.1|rcsb pdb:4BEP|rcsb pdb:4BER|rcsb pdb:4BES|rcsb pdb:4BET|interpro:IPR002110(Ankyrin)|interpro:IPR020683|interpro:IPR036770|interpro:IPR003812(Filamentation induced by cAMP protein Fic)|interpro:IPR036597	go:"GO:0005886"(plasma membrane)	-	-	figure legend:f5|comment:HaloTag-AnkXH229A accumulated less on the plasma membrane|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2020/09/28	2020/09/28	rogid:TB3sgI04Vl/d2WNLkD7OPwSjCqQ9606	rogid:97DncqzHYB0l66zqkQj9On5h/nU272624	rigid:1uxx4uEPyNwYJcw3/83CAxKXY/E	false	-	fluorescent protein tag:c-c|mutation decreasing interaction:229-229	-	-	psi-mi:"MI:0422"(immunostaining)	psi-mi:"MI:0866"(tag visualisation)
uniprotkb:Q494U1	uniprotkb:Q5ZXN6	intact:EBI-10241513|uniprotkb:Q5SV98|uniprotkb:Q9H0M7|uniprotkb:Q494U2|ensembl:ENSP00000368720	intact:EBI-26359852|ensemblbacteria:AAU26784	psi-mi:pkhn1_human(display_long)|uniprotkb:PLEKHN1(gene name)|psi-mi:PLEKHN1(display_short)|uniprotkb:CLPABP(gene name synonym)|uniprotkb:Cardiolipin and phosphatidic acid-binding protein(gene name synonym)	psi-mi:ankx_legph(display_long)|uniprotkb:ankX(gene name)|psi-mi:ankX(display_short)|uniprotkb:legA8(gene name synonym)|uniprotkb:lpg0695(locus name)|uniprotkb:Ankyrin repeat-containing protein X(gene name synonym)	psi-mi:"MI:0416"(fluorescence microscopy)	Yu et al. (2018)	imex:IM-28385|pubmed:29433439	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:272624(legph)|taxid:272624(Legionella pneumophila subsp. pneumophila)	psi-mi:"MI:0403"(colocalization)	psi-mi:"MI:0471"(MINT)	intact:EBI-26361118|imex:IM-28385-13	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001153656.1|refseq:NP_115505.2|ensembl:ENSG00000187583(gene)|ensembl:ENST00000379410(transcript)|go:"GO:0001666"(response to hypoxia)|go:"GO:0001786"(phosphatidylserine binding)|go:"GO:0005739"(mitochondrion)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005886"(plasma membrane)|go:"GO:0031966"(mitochondrial membrane)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0061158"(3'-UTR-mediated mRNA destabilization)|go:"GO:0070300"(phosphatidic acid binding)|go:"GO:1901612"(cardiolipin binding)|go:"GO:1901981"(phosphatidylinositol phosphate binding)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR037839|interpro:IPR042835|ensembl:ENST00000379407|ensembl:ENSP00000368717|ensembl:ENST00000379409|ensembl:ENSP00000368719|ensembl:ENSP00000368720	ensemblbacteria:AAU26784(transcript)|ensemblbacteria:lpg0695(gene)|go:"GO:0005576"(extracellular region)|go:"GO:0030430"(host cell cytoplasm)|go:"GO:0043087"(regulation of GTPase activity)|go:"GO:0044605"(phosphocholine transferase activity)|rcsb pdb:6SKU|refseq:YP_094731.1|rcsb pdb:4BEP|rcsb pdb:4BER|rcsb pdb:4BES|rcsb pdb:4BET|interpro:IPR002110(Ankyrin)|interpro:IPR020683|interpro:IPR036770|interpro:IPR003812(Filamentation induced by cAMP protein Fic)|interpro:IPR036597	go:"GO:0005634"(nucleus)	-	-	figure legend:f6|comment:In turn, the mCherry-AnkX491-809 fragment showed a speckled distribution in the nucleus and extensively co-localized with PLEKHN1.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2020/09/28	2020/09/28	rogid:TB3sgI04Vl/d2WNLkD7OPwSjCqQ9606	rogid:97DncqzHYB0l66zqkQj9On5h/nU272624	rigid:1uxx4uEPyNwYJcw3/83CAxKXY/E	false	-	mcherry fluorescent protein tag:c-c|binding-associated region:491-809	-	-	psi-mi:"MI:0422"(immunostaining)	psi-mi:"MI:0866"(tag visualisation)