#ID(s) interactor A ID(s) interactor B Alt. ID(s) interactor A Alt. ID(s) interactor B Alias(es) interactor A Alias(es) interactor B Interaction detection method(s) Publication 1st author(s) Publication Identifier(s) Taxid interactor A Taxid interactor B Interaction type(s) Source database(s) Interaction identifier(s) Confidence value(s) Expansion method(s) Biological role(s) interactor A Biological role(s) interactor B Experimental role(s) interactor A Experimental role(s) interactor B Type(s) interactor A Type(s) interactor B Xref(s) interactor A Xref(s) interactor B Interaction Xref(s) Annotation(s) interactor A Annotation(s) interactor B Interaction annotation(s) Host organism(s) Interaction parameter(s) Creation date Update date Checksum(s) interactor A Checksum(s) interactor B Interaction Checksum(s) Negative Feature(s) interactor A Feature(s) interactor B Stoichiometry(s) interactor A Stoichiometry(s) interactor B Identification method participant A Identification method participant B uniprotkb:A2A935 uniprotkb:P06537 intact:EBI-6268248|ensembl:ENSMUSP00000030902|uniprotkb:Q69ZD6|uniprotkb:Q6PB79|uniprotkb:Q7TPF4 intact:EBI-492753|uniprotkb:Q61628|uniprotkb:Q61629|ensembl:ENSMUSP00000025300|ensembl:ENSMUSP00000095199|ensembl:ENSMUSP00000111229|ensembl:ENSMUSP00000111233|intact:EBI-26668912|uniprotkb:E9PUR6|uniprotkb:E0ZPU5|uniprotkb:Q06VW2|uniprotkb:Q3U126|uniprotkb:Q3U2M7|uniprotkb:E9PYV1 psi-mi:prd16_mouse(display_long)|uniprotkb:PR domain zinc finger protein 16(gene name synonym)|uniprotkb:Prdm16(gene name)|psi-mi:Prdm16(display_short)|uniprotkb:Kiaa1675(gene name synonym)|uniprotkb:Mel1(gene name synonym)|uniprotkb:PR domain-containing protein 16(gene name synonym)|uniprotkb:Transcription factor MEL1(gene name synonym) psi-mi:gcr_mouse(display_long)|uniprotkb:Nuclear receptor subfamily 3 group C member 1(gene name synonym)|uniprotkb:Nr3c1(gene name)|psi-mi:Nr3c1(display_short)|uniprotkb:Grl(gene name synonym)|uniprotkb:Grl1(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Hasegawa et al. (2018) imex:IM-28720|pubmed:29320702 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-26604818|imex:IM-28720-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000039410(gene)|ensembl:ENSMUST00000030902(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005829"(cytosol)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0016235"(aggresome)|go:"GO:0017053"(transcription repressor complex)|go:"GO:0019827"(stem cell population maintenance)|go:"GO:0022008"(neurogenesis)|go:"GO:0030512"(negative regulation of transforming growth factor beta receptor signaling pathway)|go:"GO:0030853"(negative regulation of granulocyte differentiation)|go:"GO:0035019"(somatic stem cell population maintenance)|go:"GO:0043457"(regulation of cellular respiration)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0043586"(tongue development)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0046332"(SMAD binding)|go:"GO:0046872"(metal ion binding)|go:"GO:0046974"("histone methyltransferase activity (H3-K9 specific)")|go:"GO:0048468"(cell development)|go:"GO:0050872"(white fat cell differentiation)|go:"GO:0050873"(brown fat cell differentiation)|go:"GO:0060021"(roof of mouth development)|go:"GO:0070828"(heterochromatin organization)|go:"GO:0090336"(positive regulation of brown fat cell differentiation)|go:"GO:0120162"(positive regulation of cold-induced thermogenesis)|go:"GO:0140297"(DNA-binding transcription factor binding)|interpro:IPR001214(SET)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR036236|interpro:IPR044410|mint:A2A935|reactome:R-MMU-3214841|refseq:NP_001277955.1|refseq:NP_001277958.1|refseq:XP_006539236.1|refseq:NP_081780.3|dip:DIP-60593N ensembl:ENSMUSG00000024431(gene)|ensembl:ENSMUST00000025300(transcript)|ensembl:ENSMUST00000097592(transcript)|ensembl:ENSMUST00000115567(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0004879"(nuclear receptor activity)|go:"GO:0004883"(glucocorticoid receptor activity)|go:"GO:0005496"(steroid binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005815"(microtubule organizing center)|go:"GO:0005819"(spindle)|ensembl:ENSMUST00000115571(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0001046"(core promoter sequence-specific DNA binding)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|reactome:R-MMU-3371497|reactome:R-MMU-383280|reactome:R-MMU-4090294|go:"GO:0005829"(cytosol)|go:"GO:0006111"(regulation of gluconeogenesis)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0008211"(glucocorticoid metabolic process)|go:"GO:0008270"(zinc ion binding)|go:"GO:0010906"(regulation of glucose metabolic process)|go:"GO:0014049"(positive regulation of glutamate secretion)|go:"GO:0014069"(postsynaptic density)|go:"GO:0016020"(membrane)|go:"GO:0016607"(nuclear speck)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030325"(adrenal gland development)|go:"GO:0030518"(intracellular steroid hormone receptor signaling pathway)|go:"GO:0030544"(Hsp70 protein binding)|go:"GO:0030971"(receptor tyrosine kinase binding)|go:"GO:0031072"(heat shock protein binding)|go:"GO:0031914"(negative regulation of synaptic plasticity)|go:"GO:0031946"(regulation of glucocorticoid biosynthetic process)|go:"GO:0032991"(protein-containing complex)|go:"GO:0042127"(regulation of cell population proliferation)|go:"GO:0042562"(hormone binding)|go:"GO:0042711"(maternal behavior)|go:"GO:0042802"(identical protein binding)|go:"GO:0042921"(glucocorticoid receptor signaling pathway)|go:"GO:0043005"(neuron projection)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043116"(negative regulation of vascular permeability)|go:"GO:0043197"(dendritic spine)|go:"GO:0043525"(positive regulation of neuron apoptotic process)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046685"(response to arsenic-containing substance)|go:"GO:0048096"|go:"GO:0051879"(Hsp90 protein binding)|go:"GO:0060603"(mammary gland duct morphogenesis)|go:"GO:0060999"(positive regulation of dendritic spine development)|go:"GO:0061051"(positive regulation of cell growth involved in cardiac muscle cell development)|go:"GO:0071383"(cellular response to steroid hormone stimulus)|go:"GO:0071385"(cellular response to glucocorticoid stimulus)|go:"GO:0071549"(cellular response to dexamethasone stimulus)|go:"GO:0071560"(cellular response to transforming growth factor beta stimulus)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099092"(postsynaptic density, intracellular component)|go:"GO:1902895"(positive regulation of miRNA transcription)|go:"GO:1990239"(steroid hormone binding)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|go:"GO:2000324"(positive regulation of glucocorticoid receptor signaling pathway)|interpro:IPR000536(Nuclear hormone receptor, ligand-binding, core)|interpro:IPR001409(Glucocorticoid receptor)|interpro:IPR001628(Zinc finger, nuclear hormone receptor-type)|interpro:IPR001723(Steroid hormone receptor)|interpro:IPR013088(Zinc finger, NHR/GATA-type)|interpro:IPR035500|mint:P06537|rcsb pdb:3MNE|rcsb pdb:3MNO|rcsb pdb:3MNP|refseq:NP_032199.3|refseq:XP_006525721.1|refseq:XP_006525722.1|refseq:XP_006525723.1|refseq:XP_006525724.1|refseq:XP_006525725.1|refseq:XP_006525726.1|refseq:XP_006525727.1|refseq:XP_006525728.1|refseq:XP_006525729.1|refseq:XP_017173324.1|refseq:XP_017173325.1|refseq:XP_017173326.1|refseq:XP_017173327.1|dip:DIP-11N go:"GO:0005634"(nucleus) - - figure legend:F2A ST1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-adipocytes)|taxid:10090(Mus musculus) - 2020/12/10 2021/11/30 rogid:IIoKgZ/wtPhFX+h3JHXbeH2HEpg10090 rogid:BGeJbz2zNEPZBn4cdswdbgRBif410090 rigid:R7kioghQ/VgGJ/w0NAh+OXuZX6U false flag tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:A2A935 uniprotkb:Q9R0G7 intact:EBI-6268248|ensembl:ENSMUSP00000030902|uniprotkb:Q69ZD6|uniprotkb:Q6PB79|uniprotkb:Q7TPF4 intact:EBI-8412607|uniprotkb:Q6P9M5|intact:MINT-99176|ensembl:ENSMUSP00000069685|ensembl:ENSMUSP00000134747|ensembl:ENSMUSP00000134849 psi-mi:prd16_mouse(display_long)|uniprotkb:PR domain zinc finger protein 16(gene name synonym)|uniprotkb:Prdm16(gene name)|psi-mi:Prdm16(display_short)|uniprotkb:Kiaa1675(gene name synonym)|uniprotkb:Mel1(gene name synonym)|uniprotkb:PR domain-containing protein 16(gene name synonym)|uniprotkb:Transcription factor MEL1(gene name synonym) psi-mi:zeb2_mouse(display_long)|uniprotkb:Sip1(gene name synonym)|uniprotkb:Zfx1b(gene name synonym)|uniprotkb:Zfhx1b(gene name synonym)|uniprotkb:Zeb2(gene name)|psi-mi:Zeb2(display_short)|uniprotkb:Smad-interacting protein 1(gene name synonym)|uniprotkb:Zinc finger homeobox protein 1b(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Hasegawa et al. (2018) imex:IM-28720|pubmed:29320702 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-26604818|imex:IM-28720-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000039410(gene)|ensembl:ENSMUST00000030902(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005829"(cytosol)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0016235"(aggresome)|go:"GO:0017053"(transcription repressor complex)|go:"GO:0019827"(stem cell population maintenance)|go:"GO:0022008"(neurogenesis)|go:"GO:0030512"(negative regulation of transforming growth factor beta receptor signaling pathway)|go:"GO:0030853"(negative regulation of granulocyte differentiation)|go:"GO:0035019"(somatic stem cell population maintenance)|go:"GO:0043457"(regulation of cellular respiration)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0043586"(tongue development)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0046332"(SMAD binding)|go:"GO:0046872"(metal ion binding)|go:"GO:0046974"("histone methyltransferase activity (H3-K9 specific)")|go:"GO:0048468"(cell development)|go:"GO:0050872"(white fat cell differentiation)|go:"GO:0050873"(brown fat cell differentiation)|go:"GO:0060021"(roof of mouth development)|go:"GO:0070828"(heterochromatin organization)|go:"GO:0090336"(positive regulation of brown fat cell differentiation)|go:"GO:0120162"(positive regulation of cold-induced thermogenesis)|go:"GO:0140297"(DNA-binding transcription factor binding)|interpro:IPR001214(SET)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR036236|interpro:IPR044410|mint:A2A935|reactome:R-MMU-3214841|refseq:NP_001277955.1|refseq:NP_001277958.1|refseq:XP_006539236.1|refseq:NP_081780.3|dip:DIP-60593N refseq:XP_011237404.1|refseq:NP_056568.2|refseq:NP_001276450.1|refseq:XP_017173550.1|refseq:XP_017173552.1|refseq:XP_017173554.1|ensembl:ENSMUSG00000026872(gene)|ensembl:ENSMUST00000068415(transcript)|ensembl:ENSMUST00000176438(transcript)|ensembl:ENSMUST00000177302(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001755"(neural crest cell migration)|go:"GO:0001756"(somitogenesis)|go:"GO:0001843"(neural tube closure)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007417"(central nervous system development)|go:"GO:0021540"(corpus callosum morphogenesis)|go:"GO:0021766"(hippocampus development)|go:"GO:0021846"(cell proliferation in forebrain)|go:"GO:0021957"(corticospinal tract morphogenesis)|go:"GO:0030177"(positive regulation of Wnt signaling pathway)|go:"GO:0030511"(positive regulation of transforming growth factor beta receptor signaling pathway)|go:"GO:0043507"(positive regulation of JUN kinase activity)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045636"(positive regulation of melanocyte differentiation)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|go:"GO:0048023"(positive regulation of melanin biosynthetic process)|go:"GO:0048066"(developmental pigmentation)|go:"GO:0048598"(embryonic morphogenesis)|go:"GO:0048668"(collateral sprouting)|go:"GO:0048856"(anatomical structure development)|go:"GO:0050772"(positive regulation of axonogenesis)|go:"GO:0061373"(mammillary axonal complex development)|go:"GO:0070412"(R-SMAD binding)|go:"GO:0090263"(positive regulation of canonical Wnt signaling pathway)|go:"GO:0097324"(melanocyte migration)|go:"GO:1902748"(positive regulation of lens fiber cell differentiation)|go:"GO:1903056"(regulation of melanosome organization)|interpro:IPR001356(Homeobox)|interpro:IPR008598(Drought induced 19)|interpro:IPR009057(Homeodomain-like)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR036236|mint:Q9R0G7 go:"GO:0005634"(nucleus) - comment:mint|function:Transcriptional inhibitor that binds to DNA sequence 5'-CACCT-3' in different promoters. Represses transcription of E-cadherin figure legend:F2A ST1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-adipocytes)|taxid:10090(Mus musculus) - 2020/12/10 2021/11/30 rogid:IIoKgZ/wtPhFX+h3JHXbeH2HEpg10090 rogid:5qzDeje4A1w1NfUsHC6/cWO8fiA10090 rigid:R7kioghQ/VgGJ/w0NAh+OXuZX6U false flag tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:A2A935 uniprotkb:Q64318 intact:EBI-6268248|ensembl:ENSMUSP00000030902|uniprotkb:Q69ZD6|uniprotkb:Q6PB79|uniprotkb:Q7TPF4 intact:EBI-8560245|uniprotkb:A4QPD2|intact:UNK-5466074|uniprotkb:Q62519|ensembl:ENSMUSP00000025081 psi-mi:prd16_mouse(display_long)|uniprotkb:PR domain zinc finger protein 16(gene name synonym)|uniprotkb:Prdm16(gene name)|psi-mi:Prdm16(display_short)|uniprotkb:Kiaa1675(gene name synonym)|uniprotkb:Mel1(gene name synonym)|uniprotkb:PR domain-containing protein 16(gene name synonym)|uniprotkb:Transcription factor MEL1(gene name synonym) psi-mi:zeb1_mouse(display_long)|uniprotkb:Zeb1(gene name)|psi-mi:Zeb1(display_short)|uniprotkb:Tcf8(gene name synonym)|uniprotkb:Zfhx1a(gene name synonym)|uniprotkb:Zfx1a(gene name synonym)|uniprotkb:Zfx1ha(gene name synonym)|uniprotkb:Transcription factor 8(gene name synonym)|uniprotkb:Zinc finger homeobox protein 1a(gene name synonym)|uniprotkb:Delta EF1(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Hasegawa et al. (2018) imex:IM-28720|pubmed:29320702 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-26604818|imex:IM-28720-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000039410(gene)|ensembl:ENSMUST00000030902(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005829"(cytosol)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0016235"(aggresome)|go:"GO:0017053"(transcription repressor complex)|go:"GO:0019827"(stem cell population maintenance)|go:"GO:0022008"(neurogenesis)|go:"GO:0030512"(negative regulation of transforming growth factor beta receptor signaling pathway)|go:"GO:0030853"(negative regulation of granulocyte differentiation)|go:"GO:0035019"(somatic stem cell population maintenance)|go:"GO:0043457"(regulation of cellular respiration)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0043586"(tongue development)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0046332"(SMAD binding)|go:"GO:0046872"(metal ion binding)|go:"GO:0046974"("histone methyltransferase activity (H3-K9 specific)")|go:"GO:0048468"(cell development)|go:"GO:0050872"(white fat cell differentiation)|go:"GO:0050873"(brown fat cell differentiation)|go:"GO:0060021"(roof of mouth development)|go:"GO:0070828"(heterochromatin organization)|go:"GO:0090336"(positive regulation of brown fat cell differentiation)|go:"GO:0120162"(positive regulation of cold-induced thermogenesis)|go:"GO:0140297"(DNA-binding transcription factor binding)|interpro:IPR001214(SET)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR036236|interpro:IPR044410|mint:A2A935|reactome:R-MMU-3214841|refseq:NP_001277955.1|refseq:NP_001277958.1|refseq:XP_006539236.1|refseq:NP_081780.3|dip:DIP-60593N refseq:NP_035676.1|dip:DIP-60280N|ensembl:ENSMUSG00000024238(gene)|ensembl:ENSMUST00000025081(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0003682"(chromatin binding)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007389"(pattern specification process)|go:"GO:0007417"(central nervous system development)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0010464"(regulation of mesenchymal cell proliferation)|go:"GO:0017015"(regulation of transforming growth factor beta receptor signaling pathway)|go:"GO:0030154"(cell differentiation)|go:"GO:0030857"(negative regulation of epithelial cell differentiation)|go:"GO:0033081"(regulation of T cell differentiation in thymus)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045602"(negative regulation of endothelial cell differentiation)|go:"GO:0045666"(positive regulation of neuron differentiation)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|go:"GO:0048513"(animal organ development)|go:"GO:0048596"(embryonic camera-type eye morphogenesis)|go:"GO:0048598"(embryonic morphogenesis)|go:"GO:0048704"(embryonic skeletal system morphogenesis)|go:"GO:0048752"(semicircular canal morphogenesis)|go:"GO:0048856"(anatomical structure development)|go:"GO:0051150"(regulation of smooth muscle cell differentiation)|go:"GO:0051216"(cartilage development)|go:"GO:0070888"(E-box binding)|go:"GO:0071230"(cellular response to amino acid stimulus)|go:"GO:0090103"(cochlea morphogenesis)|interpro:IPR001356(Homeobox)|interpro:IPR008598(Drought induced 19)|interpro:IPR009057(Homeodomain-like)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR036236|mint:Q64318 go:"GO:0005634"(nucleus) - comment:mint|function:Acts as a transcriptional repressor. Binds to E-box sequences in the immunoglobulin heavy chain enhancer as well as in the regulatory regions of many other tissue-specific genes figure legend:F2A ST1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-adipocytes)|taxid:10090(Mus musculus) - 2020/12/10 2021/11/30 rogid:IIoKgZ/wtPhFX+h3JHXbeH2HEpg10090 rogid:WZxQkmepgvyAByjcomRjaQ9RaBg10090 rigid:R7kioghQ/VgGJ/w0NAh+OXuZX6U false flag tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:A2A935 uniprotkb:Q8BMQ2 intact:EBI-6268248|ensembl:ENSMUSP00000030902|uniprotkb:Q69ZD6|uniprotkb:Q6PB79|uniprotkb:Q7TPF4 intact:EBI-8411864|intact:MINT-4137550|uniprotkb:Q8BKZ4|uniprotkb:Q148Y1|ensembl:ENSMUSP00000042265 psi-mi:prd16_mouse(display_long)|uniprotkb:PR domain zinc finger protein 16(gene name synonym)|uniprotkb:Prdm16(gene name)|psi-mi:Prdm16(display_short)|uniprotkb:Kiaa1675(gene name synonym)|uniprotkb:Mel1(gene name synonym)|uniprotkb:PR domain-containing protein 16(gene name synonym)|uniprotkb:Transcription factor MEL1(gene name synonym) psi-mi:tf3c4_mouse(display_long)|uniprotkb:Gtf3c4(gene name)|psi-mi:Gtf3c4(display_short)|uniprotkb:TF3C-delta(gene name synonym)|uniprotkb:Transcription factor IIIC 90 kDa subunit(gene name synonym)|uniprotkb:Transcription factor IIIC subunit delta(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Hasegawa et al. (2018) imex:IM-28720|pubmed:29320702 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-26604818|imex:IM-28720-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000039410(gene)|ensembl:ENSMUST00000030902(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005829"(cytosol)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0016235"(aggresome)|go:"GO:0017053"(transcription repressor complex)|go:"GO:0019827"(stem cell population maintenance)|go:"GO:0022008"(neurogenesis)|go:"GO:0030512"(negative regulation of transforming growth factor beta receptor signaling pathway)|go:"GO:0030853"(negative regulation of granulocyte differentiation)|go:"GO:0035019"(somatic stem cell population maintenance)|go:"GO:0043457"(regulation of cellular respiration)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0043586"(tongue development)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0046332"(SMAD binding)|go:"GO:0046872"(metal ion binding)|go:"GO:0046974"("histone methyltransferase activity (H3-K9 specific)")|go:"GO:0048468"(cell development)|go:"GO:0050872"(white fat cell differentiation)|go:"GO:0050873"(brown fat cell differentiation)|go:"GO:0060021"(roof of mouth development)|go:"GO:0070828"(heterochromatin organization)|go:"GO:0090336"(positive regulation of brown fat cell differentiation)|go:"GO:0120162"(positive regulation of cold-induced thermogenesis)|go:"GO:0140297"(DNA-binding transcription factor binding)|interpro:IPR001214(SET)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR036236|interpro:IPR044410|mint:A2A935|reactome:R-MMU-3214841|refseq:NP_001277955.1|refseq:NP_001277958.1|refseq:XP_006539236.1|refseq:NP_081780.3|dip:DIP-60593N refseq:NP_766565.2|refseq:NP_001159505.1|ensembl:ENSMUSG00000035666(gene)|ensembl:ENSMUST00000037117(transcript)|go:"GO:0000127"(transcription factor TFIIIC complex)|go:"GO:0003677"(DNA binding)|go:"GO:0004402"(histone acetyltransferase activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0006384"(transcription initiation from RNA polymerase III promoter)|interpro:IPR024761|interpro:IPR024764|interpro:IPR036322|interpro:IPR044230|mint:Q8BMQ2|reactome:R-MMU-76061|reactome:R-MMU-76066 go:"GO:0005634"(nucleus) - comment:mint|function:"Essential for RNA polymerase III to make a number of small nuclear and cytoplasmic RNAs, including 5S RNA, tRNA, and adenovirus-associated (VA) RNA of both cellular and viral origin. Has histone acetyltransferase activity (HAT) with unique specificity for free and nucleosomal H3. May cooperate with GTF3C5 in facilitating the recruitment of TFIIIB and RNA polymerase through direct interactions with BRF1, POLR3C and POLR3F. May be localized close to the A box" figure legend:F2A ST1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-adipocytes)|taxid:10090(Mus musculus) - 2020/12/10 2021/11/30 rogid:IIoKgZ/wtPhFX+h3JHXbeH2HEpg10090 rogid:q+DihI8GnlWq26wz+ReBu0fpcXQ10090 rigid:R7kioghQ/VgGJ/w0NAh+OXuZX6U false flag tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:A2A935 uniprotkb:Q8BL74 intact:EBI-6268248|ensembl:ENSMUSP00000030902|uniprotkb:Q69ZD6|uniprotkb:Q6PB79|uniprotkb:Q7TPF4 intact:EBI-8377212|uniprotkb:Q9CVE6|uniprotkb:Q8K1J1|uniprotkb:Q3U7Z9|uniprotkb:Q8BLP3|uniprotkb:Q8BJJ4|uniprotkb:Q80XQ7|uniprotkb:Q9DBK6|intact:MINT-4137509|uniprotkb:Q9CSS0|ensembl:ENSMUSP00000085325 psi-mi:prd16_mouse(display_long)|uniprotkb:PR domain zinc finger protein 16(gene name synonym)|uniprotkb:Prdm16(gene name)|psi-mi:Prdm16(display_short)|uniprotkb:Kiaa1675(gene name synonym)|uniprotkb:Mel1(gene name synonym)|uniprotkb:PR domain-containing protein 16(gene name synonym)|uniprotkb:Transcription factor MEL1(gene name synonym) psi-mi:tf3c2_mouse(display_long)|uniprotkb:Gtf3c2(gene name)|psi-mi:Gtf3c2(display_short)|uniprotkb:Kiaa0011(gene name synonym)|uniprotkb:TF3C-beta(gene name synonym)|uniprotkb:Transcription factor IIIC 110 kDa subunit(gene name synonym)|uniprotkb:Transcription factor IIIC subunit beta(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Hasegawa et al. (2018) imex:IM-28720|pubmed:29320702 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-26604818|imex:IM-28720-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000039410(gene)|ensembl:ENSMUST00000030902(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005829"(cytosol)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0016235"(aggresome)|go:"GO:0017053"(transcription repressor complex)|go:"GO:0019827"(stem cell population maintenance)|go:"GO:0022008"(neurogenesis)|go:"GO:0030512"(negative regulation of transforming growth factor beta receptor signaling pathway)|go:"GO:0030853"(negative regulation of granulocyte differentiation)|go:"GO:0035019"(somatic stem cell population maintenance)|go:"GO:0043457"(regulation of cellular respiration)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0043586"(tongue development)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0046332"(SMAD binding)|go:"GO:0046872"(metal ion binding)|go:"GO:0046974"("histone methyltransferase activity (H3-K9 specific)")|go:"GO:0048468"(cell development)|go:"GO:0050872"(white fat cell differentiation)|go:"GO:0050873"(brown fat cell differentiation)|go:"GO:0060021"(roof of mouth development)|go:"GO:0070828"(heterochromatin organization)|go:"GO:0090336"(positive regulation of brown fat cell differentiation)|go:"GO:0120162"(positive regulation of cold-induced thermogenesis)|go:"GO:0140297"(DNA-binding transcription factor binding)|interpro:IPR001214(SET)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR036236|interpro:IPR044410|mint:A2A935|reactome:R-MMU-3214841|refseq:NP_001277955.1|refseq:NP_001277958.1|refseq:XP_006539236.1|refseq:NP_081780.3|dip:DIP-60593N refseq:NP_082177.2|ensembl:ENSMUSG00000106864(gene)|ensembl:ENSMUST00000088010(transcript)|go:"GO:0000127"(transcription factor TFIIIC complex)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006383"(transcription by RNA polymerase III)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019775|interpro:IPR036322|mint:Q8BL74|reactome:R-MMU-76061|reactome:R-MMU-76066 go:"GO:0005634"(nucleus) - comment:mint|function:Required for RNA polymerase III-mediated transcription. Component of TFIIIC that initiates transcription complex assembly on tRNA and is required for transcription of 5S rRNA and other stable nuclear and cytoplasmic RNAs. May play a direct role in stabilizing interactions of TFIIIC2 with TFIIIC1 figure legend:F2A ST1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-adipocytes)|taxid:10090(Mus musculus) - 2020/12/10 2021/11/30 rogid:IIoKgZ/wtPhFX+h3JHXbeH2HEpg10090 rogid:0qVV826c+vZLKAwOeJXTiaQM+4010090 rigid:R7kioghQ/VgGJ/w0NAh+OXuZX6U false flag tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:A2A935 uniprotkb:Q8K284 intact:EBI-6268248|ensembl:ENSMUSP00000030902|uniprotkb:Q69ZD6|uniprotkb:Q6PB79|uniprotkb:Q7TPF4 intact:EBI-8412484|uniprotkb:Q8CAL9|intact:MINT-4137479|ensembl:ENSMUSP00000056719 psi-mi:prd16_mouse(display_long)|uniprotkb:PR domain zinc finger protein 16(gene name synonym)|uniprotkb:Prdm16(gene name)|psi-mi:Prdm16(display_short)|uniprotkb:Kiaa1675(gene name synonym)|uniprotkb:Mel1(gene name synonym)|uniprotkb:PR domain-containing protein 16(gene name synonym)|uniprotkb:Transcription factor MEL1(gene name synonym) psi-mi:tf3c1_mouse(display_long)|uniprotkb:Gtf3c1(gene name)|psi-mi:Gtf3c1(display_short)|uniprotkb:Transcription factor IIIC subunit alpha(gene name synonym)|uniprotkb:TF3C-alpha(gene name synonym)|uniprotkb:Transcription factor IIIC 220 kDa subunit(gene name synonym)|uniprotkb:TFIIIC box B-binding subunit(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Hasegawa et al. (2018) imex:IM-28720|pubmed:29320702 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-26604818|imex:IM-28720-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000039410(gene)|ensembl:ENSMUST00000030902(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005829"(cytosol)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0016235"(aggresome)|go:"GO:0017053"(transcription repressor complex)|go:"GO:0019827"(stem cell population maintenance)|go:"GO:0022008"(neurogenesis)|go:"GO:0030512"(negative regulation of transforming growth factor beta receptor signaling pathway)|go:"GO:0030853"(negative regulation of granulocyte differentiation)|go:"GO:0035019"(somatic stem cell population maintenance)|go:"GO:0043457"(regulation of cellular respiration)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0043586"(tongue development)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0046332"(SMAD binding)|go:"GO:0046872"(metal ion binding)|go:"GO:0046974"("histone methyltransferase activity (H3-K9 specific)")|go:"GO:0048468"(cell development)|go:"GO:0050872"(white fat cell differentiation)|go:"GO:0050873"(brown fat cell differentiation)|go:"GO:0060021"(roof of mouth development)|go:"GO:0070828"(heterochromatin organization)|go:"GO:0090336"(positive regulation of brown fat cell differentiation)|go:"GO:0120162"(positive regulation of cold-induced thermogenesis)|go:"GO:0140297"(DNA-binding transcription factor binding)|interpro:IPR001214(SET)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR036236|interpro:IPR044410|mint:A2A935|reactome:R-MMU-3214841|refseq:NP_001277955.1|refseq:NP_001277958.1|refseq:XP_006539236.1|refseq:NP_081780.3|dip:DIP-60593N refseq:NP_997122.1|ensembl:ENSMUSG00000032777(gene)|ensembl:ENSMUST00000055506(transcript)|go:"GO:0000127"(transcription factor TFIIIC complex)|go:"GO:0003677"(DNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0006384"(transcription initiation from RNA polymerase III promoter)|go:"GO:0042791"(5S class rRNA transcription by RNA polymerase III)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR007309(B-block binding subunit of TFIIIC)|interpro:IPR035625|interpro:IPR044210|mint:Q8K284|reactome:R-MMU-76061|reactome:R-MMU-76066 go:"GO:0005634"(nucleus) - comment:mint|function:Required for RNA polymerase III-mediated transcription. Component of TFIIIC that initiates transcription complex assembly on tRNA and is required for transcription of 5S rRNA and other stable nuclear and cytoplasmic RNAs. Binds to the box B promoter element figure legend:F2A ST1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-adipocytes)|taxid:10090(Mus musculus) - 2020/12/10 2021/11/30 rogid:IIoKgZ/wtPhFX+h3JHXbeH2HEpg10090 rogid:vL28aV6mHktcbaTvhC+U3jxtrAY10090 rigid:R7kioghQ/VgGJ/w0NAh+OXuZX6U false flag tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:A2A935 uniprotkb:Q9JJZ6 intact:EBI-6268248|ensembl:ENSMUSP00000030902|uniprotkb:Q69ZD6|uniprotkb:Q6PB79|uniprotkb:Q7TPF4 intact:EBI-8407880|intact:MINT-4099898|uniprotkb:Q9ESX3|uniprotkb:Q9JHF8|ensembl:ENSMUSP00000067680 psi-mi:prd16_mouse(display_long)|uniprotkb:PR domain zinc finger protein 16(gene name synonym)|uniprotkb:Prdm16(gene name)|psi-mi:Prdm16(display_short)|uniprotkb:Kiaa1675(gene name synonym)|uniprotkb:Mel1(gene name synonym)|uniprotkb:PR domain-containing protein 16(gene name synonym)|uniprotkb:Transcription factor MEL1(gene name synonym) psi-mi:klf13_mouse(display_long)|uniprotkb:Klf13(gene name)|psi-mi:Klf13(display_short)|uniprotkb:Bteb3(gene name synonym)|uniprotkb:Fklf2(gene name synonym)|uniprotkb:Transcription factor BTEB3(gene name synonym)|uniprotkb:Basic transcription element-binding protein 3(gene name synonym)|uniprotkb:RANTES factor of late activated T-lymphocytes 1(gene name synonym)|uniprotkb:Erythroid transcription factor FKLF-2(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Hasegawa et al. (2018) imex:IM-28720|pubmed:29320702 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-26604818|imex:IM-28720-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000039410(gene)|ensembl:ENSMUST00000030902(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005829"(cytosol)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0016235"(aggresome)|go:"GO:0017053"(transcription repressor complex)|go:"GO:0019827"(stem cell population maintenance)|go:"GO:0022008"(neurogenesis)|go:"GO:0030512"(negative regulation of transforming growth factor beta receptor signaling pathway)|go:"GO:0030853"(negative regulation of granulocyte differentiation)|go:"GO:0035019"(somatic stem cell population maintenance)|go:"GO:0043457"(regulation of cellular respiration)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0043586"(tongue development)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0046332"(SMAD binding)|go:"GO:0046872"(metal ion binding)|go:"GO:0046974"("histone methyltransferase activity (H3-K9 specific)")|go:"GO:0048468"(cell development)|go:"GO:0050872"(white fat cell differentiation)|go:"GO:0050873"(brown fat cell differentiation)|go:"GO:0060021"(roof of mouth development)|go:"GO:0070828"(heterochromatin organization)|go:"GO:0090336"(positive regulation of brown fat cell differentiation)|go:"GO:0120162"(positive regulation of cold-induced thermogenesis)|go:"GO:0140297"(DNA-binding transcription factor binding)|interpro:IPR001214(SET)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR036236|interpro:IPR044410|mint:A2A935|reactome:R-MMU-3214841|refseq:NP_001277955.1|refseq:NP_001277958.1|refseq:XP_006539236.1|refseq:NP_081780.3|dip:DIP-60593N refseq:NP_067341.2|ensembl:ENSMUSG00000052040(gene)|ensembl:ENSMUST00000063694(transcript)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0045647"(negative regulation of erythrocyte differentiation)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR036236|mint:Q9JJZ6 go:"GO:0005634"(nucleus) - comment:mint|function:Transcription factor that activates expression from GC-rich minimal promoter regions, including genes in the cells of the erythroid lineage figure legend:F2A ST1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-adipocytes)|taxid:10090(Mus musculus) - 2020/12/10 2021/11/30 rogid:IIoKgZ/wtPhFX+h3JHXbeH2HEpg10090 rogid:hcyf/EM6gCedWmpCdPyMgxwk2e810090 rigid:R7kioghQ/VgGJ/w0NAh+OXuZX6U false flag tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:A2A935 uniprotkb:Q61286 intact:EBI-6268248|ensembl:ENSMUSP00000030902|uniprotkb:Q69ZD6|uniprotkb:Q6PB79|uniprotkb:Q7TPF4 intact:EBI-8006499|intact:MINT-2567849|uniprotkb:E9QPN4|ensembl:ENSMUSP00000139364|ensembl:ENSMUSP00000139365 psi-mi:prd16_mouse(display_long)|uniprotkb:PR domain zinc finger protein 16(gene name synonym)|uniprotkb:Prdm16(gene name)|psi-mi:Prdm16(display_short)|uniprotkb:Kiaa1675(gene name synonym)|uniprotkb:Mel1(gene name synonym)|uniprotkb:PR domain-containing protein 16(gene name synonym)|uniprotkb:Transcription factor MEL1(gene name synonym) psi-mi:htf4_mouse(display_long)|uniprotkb:Tcf12(gene name)|psi-mi:Tcf12(display_short)|uniprotkb:Alf1(gene name synonym)|uniprotkb:Meb(gene name synonym)|uniprotkb:Transcription factor HTF-4(gene name synonym)|uniprotkb:E-box-binding protein(gene name synonym)|uniprotkb:DNA-binding protein HTF4(gene name synonym)|uniprotkb:Class A helix-loop-helix transcription factor ME1(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Hasegawa et al. (2018) imex:IM-28720|pubmed:29320702 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-26604818|imex:IM-28720-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000039410(gene)|ensembl:ENSMUST00000030902(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005829"(cytosol)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0016235"(aggresome)|go:"GO:0017053"(transcription repressor complex)|go:"GO:0019827"(stem cell population maintenance)|go:"GO:0022008"(neurogenesis)|go:"GO:0030512"(negative regulation of transforming growth factor beta receptor signaling pathway)|go:"GO:0030853"(negative regulation of granulocyte differentiation)|go:"GO:0035019"(somatic stem cell population maintenance)|go:"GO:0043457"(regulation of cellular respiration)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0043586"(tongue development)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0046332"(SMAD binding)|go:"GO:0046872"(metal ion binding)|go:"GO:0046974"("histone methyltransferase activity (H3-K9 specific)")|go:"GO:0048468"(cell development)|go:"GO:0050872"(white fat cell differentiation)|go:"GO:0050873"(brown fat cell differentiation)|go:"GO:0060021"(roof of mouth development)|go:"GO:0070828"(heterochromatin organization)|go:"GO:0090336"(positive regulation of brown fat cell differentiation)|go:"GO:0120162"(positive regulation of cold-induced thermogenesis)|go:"GO:0140297"(DNA-binding transcription factor binding)|interpro:IPR001214(SET)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR036236|interpro:IPR044410|mint:A2A935|reactome:R-MMU-3214841|refseq:NP_001277955.1|refseq:NP_001277958.1|refseq:XP_006539236.1|refseq:NP_081780.3|dip:DIP-60593N refseq:NP_035674.2|refseq:NP_001240794.1|refseq:XP_006511057.1|refseq:XP_006511060.1|dip:DIP-42840N|ensembl:ENSMUSG00000032228(gene)|ensembl:ENSMUST00000183404(transcript)|ensembl:ENSMUST00000184783(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007399"(nervous system development)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0016607"(nuclear speck)|go:"GO:0030154"(cell differentiation)|go:"GO:0035497"(cAMP response element binding)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0043425"(bHLH transcription factor binding)|go:"GO:0045666"(positive regulation of neuron differentiation)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046332"(SMAD binding)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0070888"(E-box binding)|go:"GO:0071837"(HMG box domain binding)|go:"GO:0090575"(RNA polymerase II transcription regulator complex)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR011598(Helix-loop-helix DNA-binding)|interpro:IPR036638|mint:Q61286|reactome:R-MMU-525793|reactome:R-MMU-8939236 go:"GO:0005634"(nucleus) - comment:mint|function:Binds specifically to oligomers of E-box motifs. May play important roles during development of the nervous system as well as in other organ systems figure legend:F2A ST1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-adipocytes)|taxid:10090(Mus musculus) - 2020/12/10 2021/11/30 rogid:IIoKgZ/wtPhFX+h3JHXbeH2HEpg10090 rogid:RaQpcfOvnDIORBP08og33dK901w10090 rigid:R7kioghQ/VgGJ/w0NAh+OXuZX6U false flag tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:A2A935 uniprotkb:Q69Z99 intact:EBI-6268248|ensembl:ENSMUSP00000030902|uniprotkb:Q69ZD6|uniprotkb:Q6PB79|uniprotkb:Q7TPF4 intact:EBI-8338783|uniprotkb:Q3UJQ0|uniprotkb:Q3U365|intact:MINT-4110900|uniprotkb:Q5FWY0|uniprotkb:Q3UDU3|uniprotkb:Q8BJF3|ensembl:ENSMUSP00000075613 psi-mi:prd16_mouse(display_long)|uniprotkb:PR domain zinc finger protein 16(gene name synonym)|uniprotkb:Prdm16(gene name)|psi-mi:Prdm16(display_short)|uniprotkb:Kiaa1675(gene name synonym)|uniprotkb:Mel1(gene name synonym)|uniprotkb:PR domain-containing protein 16(gene name synonym)|uniprotkb:Transcription factor MEL1(gene name synonym) psi-mi:zn512_mouse(display_long)|uniprotkb:Znf512(gene name)|psi-mi:Znf512(display_short)|uniprotkb:Kiaa1805(gene name synonym)|uniprotkb:Zfp512(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Hasegawa et al. (2018) imex:IM-28720|pubmed:29320702 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-26604818|imex:IM-28720-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000039410(gene)|ensembl:ENSMUST00000030902(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005829"(cytosol)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0016235"(aggresome)|go:"GO:0017053"(transcription repressor complex)|go:"GO:0019827"(stem cell population maintenance)|go:"GO:0022008"(neurogenesis)|go:"GO:0030512"(negative regulation of transforming growth factor beta receptor signaling pathway)|go:"GO:0030853"(negative regulation of granulocyte differentiation)|go:"GO:0035019"(somatic stem cell population maintenance)|go:"GO:0043457"(regulation of cellular respiration)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0043586"(tongue development)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0046332"(SMAD binding)|go:"GO:0046872"(metal ion binding)|go:"GO:0046974"("histone methyltransferase activity (H3-K9 specific)")|go:"GO:0048468"(cell development)|go:"GO:0050872"(white fat cell differentiation)|go:"GO:0050873"(brown fat cell differentiation)|go:"GO:0060021"(roof of mouth development)|go:"GO:0070828"(heterochromatin organization)|go:"GO:0090336"(positive regulation of brown fat cell differentiation)|go:"GO:0120162"(positive regulation of cold-induced thermogenesis)|go:"GO:0140297"(DNA-binding transcription factor binding)|interpro:IPR001214(SET)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR036236|interpro:IPR044410|mint:A2A935|reactome:R-MMU-3214841|refseq:NP_001277955.1|refseq:NP_001277958.1|refseq:XP_006539236.1|refseq:NP_081780.3|dip:DIP-60593N refseq:NP_766581.2|ensembl:ENSMUSG00000062761(gene)|ensembl:ENSMUST00000076264(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0046872"(metal ion binding)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR036236|mint:Q69Z99 go:"GO:0005634"(nucleus) - comment:mint figure legend:F2A ST1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-adipocytes)|taxid:10090(Mus musculus) - 2020/12/10 2021/11/30 rogid:IIoKgZ/wtPhFX+h3JHXbeH2HEpg10090 rogid:vVo4NxC/Xu//HLdwQaWynLjymAo10090 rigid:R7kioghQ/VgGJ/w0NAh+OXuZX6U false flag tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:A2A935 uniprotkb:Q61624 intact:EBI-6268248|ensembl:ENSMUSP00000030902|uniprotkb:Q69ZD6|uniprotkb:Q6PB79|uniprotkb:Q7TPF4 intact:EBI-8373074|uniprotkb:P97475|intact:MINT-4140637|ensembl:ENSMUSP00000087106|ensembl:ENSMUSP00000126338 psi-mi:prd16_mouse(display_long)|uniprotkb:PR domain zinc finger protein 16(gene name synonym)|uniprotkb:Prdm16(gene name)|psi-mi:Prdm16(display_short)|uniprotkb:Kiaa1675(gene name synonym)|uniprotkb:Mel1(gene name synonym)|uniprotkb:PR domain-containing protein 16(gene name synonym)|uniprotkb:Transcription factor MEL1(gene name synonym) psi-mi:zn148_mouse(display_long)|uniprotkb:Znf148(gene name)|psi-mi:Znf148(display_short)|uniprotkb:Zbp89(gene name synonym)|uniprotkb:Zfp148(gene name synonym)|uniprotkb:Zinc finger DNA-binding protein 89(gene name synonym)|uniprotkb:Transcription factor ZBP-89(gene name synonym)|uniprotkb:G-rich box-binding protein(gene name synonym)|uniprotkb:Beta enolase repressor factor 1(gene name synonym)|uniprotkb:Transcription factor BFCOL1(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Hasegawa et al. (2018) imex:IM-28720|pubmed:29320702 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-26604818|imex:IM-28720-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000039410(gene)|ensembl:ENSMUST00000030902(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005829"(cytosol)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0016235"(aggresome)|go:"GO:0017053"(transcription repressor complex)|go:"GO:0019827"(stem cell population maintenance)|go:"GO:0022008"(neurogenesis)|go:"GO:0030512"(negative regulation of transforming growth factor beta receptor signaling pathway)|go:"GO:0030853"(negative regulation of granulocyte differentiation)|go:"GO:0035019"(somatic stem cell population maintenance)|go:"GO:0043457"(regulation of cellular respiration)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0043586"(tongue development)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0046332"(SMAD binding)|go:"GO:0046872"(metal ion binding)|go:"GO:0046974"("histone methyltransferase activity (H3-K9 specific)")|go:"GO:0048468"(cell development)|go:"GO:0050872"(white fat cell differentiation)|go:"GO:0050873"(brown fat cell differentiation)|go:"GO:0060021"(roof of mouth development)|go:"GO:0070828"(heterochromatin organization)|go:"GO:0090336"(positive regulation of brown fat cell differentiation)|go:"GO:0120162"(positive regulation of cold-induced thermogenesis)|go:"GO:0140297"(DNA-binding transcription factor binding)|interpro:IPR001214(SET)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR036236|interpro:IPR044410|mint:A2A935|reactome:R-MMU-3214841|refseq:NP_001277955.1|refseq:NP_001277958.1|refseq:XP_006539236.1|refseq:NP_081780.3|dip:DIP-60593N refseq:NP_035879.1|refseq:XP_006522165.1|refseq:XP_017172469.1|ensembl:ENSMUSG00000022811(gene)|ensembl:ENSMUST00000089677(transcript)|ensembl:ENSMUST00000165418(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007276"(gamete generation)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|go:"GO:0065003"(protein-containing complex assembly)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR036236|mint:Q61624 go:"GO:0005634"(nucleus) - function:Involved in transcriptional regulation. Represses the transcription of a number of genes including gastrin, stromelysin and enolase. Binds to the G-rich box in the enhancer region of these genes|comment:mint figure legend:F2A ST1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-adipocytes)|taxid:10090(Mus musculus) - 2020/12/10 2021/11/30 rogid:IIoKgZ/wtPhFX+h3JHXbeH2HEpg10090 rogid:dKMlQftm4R1lfsJ/nY9CGkbeVr810090 rigid:R7kioghQ/VgGJ/w0NAh+OXuZX6U false flag tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:A2A935 uniprotkb:P70121 intact:EBI-6268248|ensembl:ENSMUSP00000030902|uniprotkb:Q69ZD6|uniprotkb:Q6PB79|uniprotkb:Q7TPF4 intact:EBI-26604727|ensembl:ENSMUSP00000066201|ensembl:ENSMUSP00000105797|ensembl:ENSMUSP00000134844|uniprotkb:Q8BQ68|uniprotkb:Q8C6T4|uniprotkb:Q8CJG3 psi-mi:prd16_mouse(display_long)|uniprotkb:PR domain zinc finger protein 16(gene name synonym)|uniprotkb:Prdm16(gene name)|psi-mi:Prdm16(display_short)|uniprotkb:Kiaa1675(gene name synonym)|uniprotkb:Mel1(gene name synonym)|uniprotkb:PR domain-containing protein 16(gene name synonym)|uniprotkb:Transcription factor MEL1(gene name synonym) psi-mi:zhx1_mouse(display_long)|uniprotkb:Zhx1(gene name)|psi-mi:Zhx1(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Hasegawa et al. (2018) imex:IM-28720|pubmed:29320702 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-26604818|imex:IM-28720-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000039410(gene)|ensembl:ENSMUST00000030902(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005829"(cytosol)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0016235"(aggresome)|go:"GO:0017053"(transcription repressor complex)|go:"GO:0019827"(stem cell population maintenance)|go:"GO:0022008"(neurogenesis)|go:"GO:0030512"(negative regulation of transforming growth factor beta receptor signaling pathway)|go:"GO:0030853"(negative regulation of granulocyte differentiation)|go:"GO:0035019"(somatic stem cell population maintenance)|go:"GO:0043457"(regulation of cellular respiration)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0043586"(tongue development)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0046332"(SMAD binding)|go:"GO:0046872"(metal ion binding)|go:"GO:0046974"("histone methyltransferase activity (H3-K9 specific)")|go:"GO:0048468"(cell development)|go:"GO:0050872"(white fat cell differentiation)|go:"GO:0050873"(brown fat cell differentiation)|go:"GO:0060021"(roof of mouth development)|go:"GO:0070828"(heterochromatin organization)|go:"GO:0090336"(positive regulation of brown fat cell differentiation)|go:"GO:0120162"(positive regulation of cold-induced thermogenesis)|go:"GO:0140297"(DNA-binding transcription factor binding)|interpro:IPR001214(SET)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR036236|interpro:IPR044410|mint:A2A935|reactome:R-MMU-3214841|refseq:NP_001277955.1|refseq:NP_001277958.1|refseq:XP_006539236.1|refseq:NP_081780.3|dip:DIP-60593N ensembl:ENSMUSG00000022361(gene)|ensembl:ENSMUST00000070143(transcript)|ensembl:ENSMUST00000110168(transcript)|ensembl:ENSMUST00000175805(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0046872"(metal ion binding)|go:"GO:0046982"(protein heterodimerization activity)|interpro:IPR001356(Homeobox)|interpro:IPR009057(Homeodomain-like)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR024578|interpro:IPR036236|interpro:IPR041057|mint:P70121|go:"GO:0005634"(nucleus)|refseq:NP_001035903.1|refseq:NP_033598.2 go:"GO:0005634"(nucleus) - - figure legend:F2A ST1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-adipocytes)|taxid:10090(Mus musculus) - 2020/12/10 2021/11/30 rogid:IIoKgZ/wtPhFX+h3JHXbeH2HEpg10090 rogid:0/6d+TdFYZ2IgO7LyXuerK/N2S410090 rigid:R7kioghQ/VgGJ/w0NAh+OXuZX6U false flag tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:A2A935 uniprotkb:Q9JJN2 intact:EBI-6268248|ensembl:ENSMUSP00000030902|uniprotkb:Q69ZD6|uniprotkb:Q6PB79|uniprotkb:Q7TPF4 intact:EBI-26604705 psi-mi:prd16_mouse(display_long)|uniprotkb:PR domain zinc finger protein 16(gene name synonym)|uniprotkb:Prdm16(gene name)|psi-mi:Prdm16(display_short)|uniprotkb:Kiaa1675(gene name synonym)|uniprotkb:Mel1(gene name synonym)|uniprotkb:PR domain-containing protein 16(gene name synonym)|uniprotkb:Transcription factor MEL1(gene name synonym) psi-mi:zfhx4_mouse(display_long)|uniprotkb:Zinc finger homeodomain protein 4(gene name synonym)|uniprotkb:Zfhx4(gene name)|psi-mi:Zfhx4(display_short)|uniprotkb:Zfh4(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Hasegawa et al. (2018) imex:IM-28720|pubmed:29320702 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-26604818|imex:IM-28720-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000039410(gene)|ensembl:ENSMUST00000030902(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005829"(cytosol)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0016235"(aggresome)|go:"GO:0017053"(transcription repressor complex)|go:"GO:0019827"(stem cell population maintenance)|go:"GO:0022008"(neurogenesis)|go:"GO:0030512"(negative regulation of transforming growth factor beta receptor signaling pathway)|go:"GO:0030853"(negative regulation of granulocyte differentiation)|go:"GO:0035019"(somatic stem cell population maintenance)|go:"GO:0043457"(regulation of cellular respiration)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0043586"(tongue development)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0046332"(SMAD binding)|go:"GO:0046872"(metal ion binding)|go:"GO:0046974"("histone methyltransferase activity (H3-K9 specific)")|go:"GO:0048468"(cell development)|go:"GO:0050872"(white fat cell differentiation)|go:"GO:0050873"(brown fat cell differentiation)|go:"GO:0060021"(roof of mouth development)|go:"GO:0070828"(heterochromatin organization)|go:"GO:0090336"(positive regulation of brown fat cell differentiation)|go:"GO:0120162"(positive regulation of cold-induced thermogenesis)|go:"GO:0140297"(DNA-binding transcription factor binding)|interpro:IPR001214(SET)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR036236|interpro:IPR044410|mint:A2A935|reactome:R-MMU-3214841|refseq:NP_001277955.1|refseq:NP_001277958.1|refseq:XP_006539236.1|refseq:NP_081780.3|dip:DIP-60593N go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0008270"(zinc ion binding)|rcsb pdb:2YRK|mint:Q9JJN2|interpro:IPR009057(Homeodomain-like)|interpro:IPR017970|interpro:IPR001356(Homeobox)|interpro:IPR003604(Zinc finger, U1-type)|interpro:IPR036236|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding) go:"GO:0005634"(nucleus) - - figure legend:F2A ST1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-adipocytes)|taxid:10090(Mus musculus) - 2020/12/10 2021/11/30 rogid:IIoKgZ/wtPhFX+h3JHXbeH2HEpg10090 rogid:0pi3vSglDsRzKYK3Ksqcvry6mpo10090 rigid:R7kioghQ/VgGJ/w0NAh+OXuZX6U false flag tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:A2A935 uniprotkb:Q61329 intact:EBI-6268248|ensembl:ENSMUSP00000030902|uniprotkb:Q69ZD6|uniprotkb:Q6PB79|uniprotkb:Q7TPF4 intact:EBI-3044000 psi-mi:prd16_mouse(display_long)|uniprotkb:PR domain zinc finger protein 16(gene name synonym)|uniprotkb:Prdm16(gene name)|psi-mi:Prdm16(display_short)|uniprotkb:Kiaa1675(gene name synonym)|uniprotkb:Mel1(gene name synonym)|uniprotkb:PR domain-containing protein 16(gene name synonym)|uniprotkb:Transcription factor MEL1(gene name synonym) psi-mi:zfhx3_mouse(display_long)|uniprotkb:Zfhx3(gene name)|psi-mi:Zfhx3(display_short)|uniprotkb:Atbf1(gene name synonym)|uniprotkb:AT-binding transcription factor 1(gene name synonym)|uniprotkb:Alpha-fetoprotein enhancer-binding protein(gene name synonym)|uniprotkb:Zinc finger homeodomain protein 3(gene name synonym)|uniprotkb:AT motif-binding factor 1(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Hasegawa et al. (2018) imex:IM-28720|pubmed:29320702 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-26604818|imex:IM-28720-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000039410(gene)|ensembl:ENSMUST00000030902(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005829"(cytosol)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0016235"(aggresome)|go:"GO:0017053"(transcription repressor complex)|go:"GO:0019827"(stem cell population maintenance)|go:"GO:0022008"(neurogenesis)|go:"GO:0030512"(negative regulation of transforming growth factor beta receptor signaling pathway)|go:"GO:0030853"(negative regulation of granulocyte differentiation)|go:"GO:0035019"(somatic stem cell population maintenance)|go:"GO:0043457"(regulation of cellular respiration)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0043586"(tongue development)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0046332"(SMAD binding)|go:"GO:0046872"(metal ion binding)|go:"GO:0046974"("histone methyltransferase activity (H3-K9 specific)")|go:"GO:0048468"(cell development)|go:"GO:0050872"(white fat cell differentiation)|go:"GO:0050873"(brown fat cell differentiation)|go:"GO:0060021"(roof of mouth development)|go:"GO:0070828"(heterochromatin organization)|go:"GO:0090336"(positive regulation of brown fat cell differentiation)|go:"GO:0120162"(positive regulation of cold-induced thermogenesis)|go:"GO:0140297"(DNA-binding transcription factor binding)|interpro:IPR001214(SET)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR036236|interpro:IPR044410|mint:A2A935|reactome:R-MMU-3214841|refseq:NP_001277955.1|refseq:NP_001277958.1|refseq:XP_006539236.1|refseq:NP_081780.3|dip:DIP-60593N go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007420"(brain development)|go:"GO:0007517"(muscle organ development)|go:"GO:0008270"(zinc ion binding)|go:"GO:0016604"(nuclear body)|go:"GO:0019899"(enzyme binding)|go:"GO:0032922"(circadian regulation of gene expression)|go:"GO:0045662"(negative regulation of myoblast differentiation)|go:"GO:0045663"(positive regulation of myoblast differentiation)|go:"GO:0045664"(regulation of neuron differentiation)|go:"GO:0045785"(positive regulation of cell adhesion)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0071559"(response to transforming growth factor beta)|go:"GO:1904059"(regulation of locomotor rhythm)|reactome:R-MMU-8941855|interpro:IPR001356(Homeobox)|interpro:IPR017970|interpro:IPR009057(Homeodomain-like)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR003604(Zinc finger, U1-type)|mint:Q61329|interpro:IPR036236 go:"GO:0005634"(nucleus) - - figure legend:F2A ST1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-adipocytes)|taxid:10090(Mus musculus) - 2020/12/10 2021/11/30 rogid:IIoKgZ/wtPhFX+h3JHXbeH2HEpg10090 rogid:6AtY2Ky7b/XXkctmkwsSoPvWWmw10090 rigid:R7kioghQ/VgGJ/w0NAh+OXuZX6U false flag tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:A2A935 uniprotkb:Q64321 intact:EBI-6268248|ensembl:ENSMUSP00000030902|uniprotkb:Q69ZD6|uniprotkb:Q6PB79|uniprotkb:Q7TPF4 intact:EBI-642868|uniprotkb:Q80VV5|ensembl:ENSMUSP00000103055|ensembl:ENSMUSP00000103056|ensembl:ENSMUSP00000103058|ensembl:ENSMUSP00000029677 psi-mi:prd16_mouse(display_long)|uniprotkb:PR domain zinc finger protein 16(gene name synonym)|uniprotkb:Prdm16(gene name)|psi-mi:Prdm16(display_short)|uniprotkb:Kiaa1675(gene name synonym)|uniprotkb:Mel1(gene name synonym)|uniprotkb:PR domain-containing protein 16(gene name synonym)|uniprotkb:Transcription factor MEL1(gene name synonym) psi-mi:zbt7b_mouse(display_long)|uniprotkb:Zinc finger protein 67(gene name synonym)|uniprotkb:Zinc finger protein Th-POK(gene name synonym)|uniprotkb:T-helper-inducing POZ/Krueppel-like factor(gene name synonym)|uniprotkb:Krueppel-related zinc finger protein cKrox(gene name synonym)|uniprotkb:Zbtb7b(gene name)|psi-mi:Zbtb7b(display_short)|uniprotkb:Thpok(gene name synonym)|uniprotkb:Zfp67(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Hasegawa et al. (2018) imex:IM-28720|pubmed:29320702 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-26604818|imex:IM-28720-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000039410(gene)|ensembl:ENSMUST00000030902(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005829"(cytosol)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0016235"(aggresome)|go:"GO:0017053"(transcription repressor complex)|go:"GO:0019827"(stem cell population maintenance)|go:"GO:0022008"(neurogenesis)|go:"GO:0030512"(negative regulation of transforming growth factor beta receptor signaling pathway)|go:"GO:0030853"(negative regulation of granulocyte differentiation)|go:"GO:0035019"(somatic stem cell population maintenance)|go:"GO:0043457"(regulation of cellular respiration)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0043586"(tongue development)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0046332"(SMAD binding)|go:"GO:0046872"(metal ion binding)|go:"GO:0046974"("histone methyltransferase activity (H3-K9 specific)")|go:"GO:0048468"(cell development)|go:"GO:0050872"(white fat cell differentiation)|go:"GO:0050873"(brown fat cell differentiation)|go:"GO:0060021"(roof of mouth development)|go:"GO:0070828"(heterochromatin organization)|go:"GO:0090336"(positive regulation of brown fat cell differentiation)|go:"GO:0120162"(positive regulation of cold-induced thermogenesis)|go:"GO:0140297"(DNA-binding transcription factor binding)|interpro:IPR001214(SET)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR036236|interpro:IPR044410|mint:A2A935|reactome:R-MMU-3214841|refseq:NP_001277955.1|refseq:NP_001277958.1|refseq:XP_006539236.1|refseq:NP_081780.3|dip:DIP-60593N refseq:NP_033591.2|refseq:XP_006501376.1|refseq:XP_006501377.1|refseq:XP_006501379.1|refseq:XP_006501380.1|refseq:XP_006501381.1|refseq:XP_006501382.1|ensembl:ENSMUSG00000028042(gene)|ensembl:ENSMUST00000029677(transcript)|ensembl:ENSMUST00000107432(transcript)|ensembl:ENSMUST00000107433(transcript)|ensembl:ENSMUST00000107435(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0000987"(cis-regulatory region sequence-specific DNA binding)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001865"(NK T cell differentiation)|go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007595"(lactation)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0031065"(positive regulation of histone deacetylation)|go:"GO:0032740"(positive regulation of interleukin-17 production)|go:"GO:0032868"(response to insulin)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:1990845"(adaptive thermogenesis)|go:"GO:0043370"(regulation of CD4-positive, alpha-beta T cell differentiation)|go:"GO:0043372"(positive regulation of CD4-positive, alpha-beta T cell differentiation)|go:"GO:0043376"(regulation of CD8-positive, alpha-beta T cell differentiation)|go:"GO:0043377"(negative regulation of CD8-positive, alpha-beta T cell differentiation)|go:"GO:2000320"(negative regulation of T-helper 17 cell differentiation)|go:"GO:2000640"(positive regulation of SREBP signaling pathway)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|interpro:IPR000210(BTB/POZ-like)|go:"GO:0046628"(positive regulation of insulin receptor signaling pathway)|go:"GO:0046872"(metal ion binding)|go:"GO:0051141"(negative regulation of NK T cell proliferation)|interpro:IPR011333(BTB/POZ fold)|go:"GO:0090336"(positive regulation of brown fat cell differentiation)|go:"GO:0120162"(positive regulation of cold-induced thermogenesis)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR036236|mint:Q64321 go:"GO:0005634"(nucleus) - - figure legend:F2A ST1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-adipocytes)|taxid:10090(Mus musculus) - 2020/12/10 2021/11/30 rogid:IIoKgZ/wtPhFX+h3JHXbeH2HEpg10090 rogid:sU1MIrKZnvkMEoOdVf75ZNnmwoQ10090 rigid:R7kioghQ/VgGJ/w0NAh+OXuZX6U false flag tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:A2A935 uniprotkb:Q925H1 intact:EBI-6268248|ensembl:ENSMUSP00000030902|uniprotkb:Q69ZD6|uniprotkb:Q6PB79|uniprotkb:Q7TPF4 intact:EBI-10953327 psi-mi:prd16_mouse(display_long)|uniprotkb:PR domain zinc finger protein 16(gene name synonym)|uniprotkb:Prdm16(gene name)|psi-mi:Prdm16(display_short)|uniprotkb:Kiaa1675(gene name synonym)|uniprotkb:Mel1(gene name synonym)|uniprotkb:PR domain-containing protein 16(gene name synonym)|uniprotkb:Transcription factor MEL1(gene name synonym) psi-mi:trps1_mouse(display_long)|uniprotkb:Trps1(gene name)|psi-mi:Trps1(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Hasegawa et al. (2018) imex:IM-28720|pubmed:29320702 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-26604818|imex:IM-28720-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000039410(gene)|ensembl:ENSMUST00000030902(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005829"(cytosol)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0016235"(aggresome)|go:"GO:0017053"(transcription repressor complex)|go:"GO:0019827"(stem cell population maintenance)|go:"GO:0022008"(neurogenesis)|go:"GO:0030512"(negative regulation of transforming growth factor beta receptor signaling pathway)|go:"GO:0030853"(negative regulation of granulocyte differentiation)|go:"GO:0035019"(somatic stem cell population maintenance)|go:"GO:0043457"(regulation of cellular respiration)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0043586"(tongue development)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0046332"(SMAD binding)|go:"GO:0046872"(metal ion binding)|go:"GO:0046974"("histone methyltransferase activity (H3-K9 specific)")|go:"GO:0048468"(cell development)|go:"GO:0050872"(white fat cell differentiation)|go:"GO:0050873"(brown fat cell differentiation)|go:"GO:0060021"(roof of mouth development)|go:"GO:0070828"(heterochromatin organization)|go:"GO:0090336"(positive regulation of brown fat cell differentiation)|go:"GO:0120162"(positive regulation of cold-induced thermogenesis)|go:"GO:0140297"(DNA-binding transcription factor binding)|interpro:IPR001214(SET)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR036236|interpro:IPR044410|mint:A2A935|reactome:R-MMU-3214841|refseq:NP_001277955.1|refseq:NP_001277958.1|refseq:XP_006539236.1|refseq:NP_081780.3|dip:DIP-60593N mint:Q925H1|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR028440|interpro:IPR000679(Zinc finger, GATA-type)|interpro:IPR013088(Zinc finger, NHR/GATA-type)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0001501"(skeletal system development)|go:"GO:0001942"(hair follicle development)|go:"GO:0002062"(chondrocyte differentiation)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007178"(transmembrane receptor protein serine/threonine kinase signaling pathway)|go:"GO:0008270"(zinc ion binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0032330"(regulation of chondrocyte differentiation)|go:"GO:0032991"(protein-containing complex)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:1902043"(positive regulation of extrinsic apoptotic signaling pathway via death domain receptors)|interpro:IPR036236 go:"GO:0005634"(nucleus) - - figure legend:F2A ST1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-adipocytes)|taxid:10090(Mus musculus) - 2020/12/10 2021/11/30 rogid:IIoKgZ/wtPhFX+h3JHXbeH2HEpg10090 rogid:quP2SG852Pp3qumt8K9m/FYGVBI10090 rigid:R7kioghQ/VgGJ/w0NAh+OXuZX6U false flag tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:A2A935 uniprotkb:Q8R2T8 intact:EBI-6268248|ensembl:ENSMUSP00000030902|uniprotkb:Q69ZD6|uniprotkb:Q6PB79|uniprotkb:Q7TPF4 intact:EBI-11516726|uniprotkb:Q8BLE3|uniprotkb:Q8R0D0|ensembl:ENSMUSP00000109521 psi-mi:prd16_mouse(display_long)|uniprotkb:PR domain zinc finger protein 16(gene name synonym)|uniprotkb:Prdm16(gene name)|psi-mi:Prdm16(display_short)|uniprotkb:Kiaa1675(gene name synonym)|uniprotkb:Mel1(gene name synonym)|uniprotkb:PR domain-containing protein 16(gene name synonym)|uniprotkb:Transcription factor MEL1(gene name synonym) psi-mi:tf3c5_mouse(display_long)|uniprotkb:TF3C-epsilon(gene name synonym)|uniprotkb:Transcription factor IIIC 63 kDa subunit(gene name synonym)|uniprotkb:Transcription factor IIIC subunit epsilon(gene name synonym)|uniprotkb:Gtf3c5(gene name)|psi-mi:Gtf3c5(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Hasegawa et al. (2018) imex:IM-28720|pubmed:29320702 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-26604818|imex:IM-28720-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000039410(gene)|ensembl:ENSMUST00000030902(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005829"(cytosol)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0016235"(aggresome)|go:"GO:0017053"(transcription repressor complex)|go:"GO:0019827"(stem cell population maintenance)|go:"GO:0022008"(neurogenesis)|go:"GO:0030512"(negative regulation of transforming growth factor beta receptor signaling pathway)|go:"GO:0030853"(negative regulation of granulocyte differentiation)|go:"GO:0035019"(somatic stem cell population maintenance)|go:"GO:0043457"(regulation of cellular respiration)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0043586"(tongue development)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0046332"(SMAD binding)|go:"GO:0046872"(metal ion binding)|go:"GO:0046974"("histone methyltransferase activity (H3-K9 specific)")|go:"GO:0048468"(cell development)|go:"GO:0050872"(white fat cell differentiation)|go:"GO:0050873"(brown fat cell differentiation)|go:"GO:0060021"(roof of mouth development)|go:"GO:0070828"(heterochromatin organization)|go:"GO:0090336"(positive regulation of brown fat cell differentiation)|go:"GO:0120162"(positive regulation of cold-induced thermogenesis)|go:"GO:0140297"(DNA-binding transcription factor binding)|interpro:IPR001214(SET)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR036236|interpro:IPR044410|mint:A2A935|reactome:R-MMU-3214841|refseq:NP_001277955.1|refseq:NP_001277958.1|refseq:XP_006539236.1|refseq:NP_081780.3|dip:DIP-60593N refseq:NP_001277413.1|refseq:NP_683730.1|ensembl:ENSMUSG00000026816(gene)|ensembl:ENSMUST00000113889(transcript)|go:"GO:0000127"(transcription factor TFIIIC complex)|go:"GO:0003677"(DNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006384"(transcription initiation from RNA polymerase III promoter)|go:"GO:0035914"(skeletal muscle cell differentiation)|interpro:IPR019136|interpro:IPR040454|interpro:IPR041499|interpro:IPR042536|mint:Q8R2T8|reactome:R-MMU-76061|reactome:R-MMU-76066 go:"GO:0005634"(nucleus) - - figure legend:F2A ST1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-adipocytes)|taxid:10090(Mus musculus) - 2020/12/10 2021/11/30 rogid:IIoKgZ/wtPhFX+h3JHXbeH2HEpg10090 rogid:d9jKi16JoEdZRlL74RmmQCfmT4I10090 rigid:R7kioghQ/VgGJ/w0NAh+OXuZX6U false flag tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:A2A935 uniprotkb:Q00417 intact:EBI-6268248|ensembl:ENSMUSP00000030902|uniprotkb:Q69ZD6|uniprotkb:Q6PB79|uniprotkb:Q7TPF4 intact:EBI-6394469 psi-mi:prd16_mouse(display_long)|uniprotkb:PR domain zinc finger protein 16(gene name synonym)|uniprotkb:Prdm16(gene name)|psi-mi:Prdm16(display_short)|uniprotkb:Kiaa1675(gene name synonym)|uniprotkb:Mel1(gene name synonym)|uniprotkb:PR domain-containing protein 16(gene name synonym)|uniprotkb:Transcription factor MEL1(gene name synonym) psi-mi:tcf7_mouse(display_long)|uniprotkb:Tcf7(gene name)|psi-mi:Tcf7(display_short)|uniprotkb:Tcf-1(gene name synonym)|uniprotkb:Tcf1(gene name synonym)|uniprotkb:T-cell-specific transcription factor 1(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Hasegawa et al. (2018) imex:IM-28720|pubmed:29320702 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-26604818|imex:IM-28720-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000039410(gene)|ensembl:ENSMUST00000030902(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005829"(cytosol)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0016235"(aggresome)|go:"GO:0017053"(transcription repressor complex)|go:"GO:0019827"(stem cell population maintenance)|go:"GO:0022008"(neurogenesis)|go:"GO:0030512"(negative regulation of transforming growth factor beta receptor signaling pathway)|go:"GO:0030853"(negative regulation of granulocyte differentiation)|go:"GO:0035019"(somatic stem cell population maintenance)|go:"GO:0043457"(regulation of cellular respiration)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0043586"(tongue development)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0046332"(SMAD binding)|go:"GO:0046872"(metal ion binding)|go:"GO:0046974"("histone methyltransferase activity (H3-K9 specific)")|go:"GO:0048468"(cell development)|go:"GO:0050872"(white fat cell differentiation)|go:"GO:0050873"(brown fat cell differentiation)|go:"GO:0060021"(roof of mouth development)|go:"GO:0070828"(heterochromatin organization)|go:"GO:0090336"(positive regulation of brown fat cell differentiation)|go:"GO:0120162"(positive regulation of cold-induced thermogenesis)|go:"GO:0140297"(DNA-binding transcription factor binding)|interpro:IPR001214(SET)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR036236|interpro:IPR044410|mint:A2A935|reactome:R-MMU-3214841|refseq:NP_001277955.1|refseq:NP_001277958.1|refseq:XP_006539236.1|refseq:NP_081780.3|dip:DIP-60593N refseq:NP_001300910.1|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000791"(euchromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001217"(DNA-binding transcription repressor activity)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0021915"(neural tube development)|go:"GO:0033153"("T cell receptor V(D)J recombination")|go:"GO:0042127"(regulation of cell population proliferation)|go:"GO:0042492"(gamma-delta T cell differentiation)|go:"GO:0044336"(canonical Wnt signaling pathway involved in negative regulation of apoptotic process)|go:"GO:0045586"(regulation of gamma-delta T cell differentiation)|go:"GO:0046632"(alpha-beta T cell differentiation)|go:"GO:0048557"(embryonic digestive tract morphogenesis)|go:"GO:0048619"(embryonic hindgut morphogenesis)|go:"GO:0060070"(canonical Wnt signaling pathway)|go:"GO:1990907"(beta-catenin-TCF complex)|reactome:R-MMU-201722|reactome:R-MMU-3769402|reactome:R-MMU-4086398|reactome:R-MMU-4641265|reactome:R-MMU-8853884|reactome:R-MMU-8951430|go:"GO:0030538"(embryonic genitalia morphogenesis)|mint:Q00417|interpro:IPR013558(CTNNB1 binding, N-teminal)|interpro:IPR009071(High mobility group box, HMG)|interpro:IPR024940|refseq:NP_033357.1|interpro:IPR028785|interpro:IPR027397|interpro:IPR036910 go:"GO:0005634"(nucleus) - - figure legend:F2A ST1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-adipocytes)|taxid:10090(Mus musculus) - 2020/12/10 2021/11/30 rogid:IIoKgZ/wtPhFX+h3JHXbeH2HEpg10090 rogid:UmgdAeS+PUiRX80iBI1VGuTOM+c10090 rigid:R7kioghQ/VgGJ/w0NAh+OXuZX6U false flag tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:A2A935 uniprotkb:P48381 intact:EBI-6268248|ensembl:ENSMUSP00000030902|uniprotkb:Q69ZD6|uniprotkb:Q6PB79|uniprotkb:Q7TPF4 intact:EBI-6123284|uniprotkb:Q8BLW2|uniprotkb:Q8C0R3|uniprotkb:Q8VBY6|ensembl:ENSMUSP00000126313|ensembl:ENSMUSP00000133461|ensembl:ENSMUSP00000134141 psi-mi:prd16_mouse(display_long)|uniprotkb:PR domain zinc finger protein 16(gene name synonym)|uniprotkb:Prdm16(gene name)|psi-mi:Prdm16(display_short)|uniprotkb:Kiaa1675(gene name synonym)|uniprotkb:Mel1(gene name synonym)|uniprotkb:PR domain-containing protein 16(gene name synonym)|uniprotkb:Transcription factor MEL1(gene name synonym) psi-mi:rfx3_mouse(display_long)|uniprotkb:Rfx3(gene name)|psi-mi:Rfx3(display_short)|uniprotkb:Regulatory factor X 3(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Hasegawa et al. (2018) imex:IM-28720|pubmed:29320702 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-26604818|imex:IM-28720-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000039410(gene)|ensembl:ENSMUST00000030902(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005829"(cytosol)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0016235"(aggresome)|go:"GO:0017053"(transcription repressor complex)|go:"GO:0019827"(stem cell population maintenance)|go:"GO:0022008"(neurogenesis)|go:"GO:0030512"(negative regulation of transforming growth factor beta receptor signaling pathway)|go:"GO:0030853"(negative regulation of granulocyte differentiation)|go:"GO:0035019"(somatic stem cell population maintenance)|go:"GO:0043457"(regulation of cellular respiration)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0043586"(tongue development)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0046332"(SMAD binding)|go:"GO:0046872"(metal ion binding)|go:"GO:0046974"("histone methyltransferase activity (H3-K9 specific)")|go:"GO:0048468"(cell development)|go:"GO:0050872"(white fat cell differentiation)|go:"GO:0050873"(brown fat cell differentiation)|go:"GO:0060021"(roof of mouth development)|go:"GO:0070828"(heterochromatin organization)|go:"GO:0090336"(positive regulation of brown fat cell differentiation)|go:"GO:0120162"(positive regulation of cold-induced thermogenesis)|go:"GO:0140297"(DNA-binding transcription factor binding)|interpro:IPR001214(SET)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR036236|interpro:IPR044410|mint:A2A935|reactome:R-MMU-3214841|refseq:NP_001277955.1|refseq:NP_001277958.1|refseq:XP_006539236.1|refseq:NP_081780.3|dip:DIP-60593N refseq:XP_011245471.1|refseq:NP_001159886.1|refseq:NP_035395.2|refseq:XP_006526845.1|ensembl:ENSMUSG00000040929(gene)|ensembl:ENSMUST00000165566(transcript)|ensembl:ENSMUST00000172907(transcript)|ensembl:ENSMUST00000174850(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005576"(extracellular region)|go:"GO:0005634"(nucleus)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007368"(determination of left/right symmetry)|go:"GO:0031018"(endocrine pancreas development)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048469"(cell maturation)|go:"GO:0050796"(regulation of insulin secretion)|go:"GO:0060271"(cilium assembly)|go:"GO:0060285"(cilium-dependent cell motility)|go:"GO:0060287"(epithelial cilium movement involved in determination of left/right asymmetry)|go:"GO:0072560"(type B pancreatic cell maturation)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|go:"GO:2000078"(positive regulation of type B pancreatic cell development)|interpro:IPR003150(DNA-binding RFX)|interpro:IPR007668(RFX1 transcription activation region)|interpro:IPR036388|interpro:IPR036390|interpro:IPR039779|mint:P48381 go:"GO:0005634"(nucleus) - - figure legend:F2A ST1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-adipocytes)|taxid:10090(Mus musculus) - 2020/12/10 2021/11/30 rogid:IIoKgZ/wtPhFX+h3JHXbeH2HEpg10090 rogid:n61SA45VD1vA0KpE7K2juAkIOIw10090 rigid:R7kioghQ/VgGJ/w0NAh+OXuZX6U false flag tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:A2A935 uniprotkb:Q8VIG1 intact:EBI-6268248|ensembl:ENSMUSP00000030902|uniprotkb:Q69ZD6|uniprotkb:Q6PB79|uniprotkb:Q7TPF4 intact:EBI-2312802|uniprotkb:A0JNY8|uniprotkb:Q155C6|uniprotkb:Q3U0W0|uniprotkb:Q4VAD6|uniprotkb:Q9CW43|ensembl:ENSMUSP00000079231|ensembl:ENSMUSP00000109076 psi-mi:prd16_mouse(display_long)|uniprotkb:PR domain zinc finger protein 16(gene name synonym)|uniprotkb:Prdm16(gene name)|psi-mi:Prdm16(display_short)|uniprotkb:Kiaa1675(gene name synonym)|uniprotkb:Mel1(gene name synonym)|uniprotkb:PR domain-containing protein 16(gene name synonym)|uniprotkb:Transcription factor MEL1(gene name synonym) psi-mi:rest_mouse(display_long)|uniprotkb:Rest(gene name)|psi-mi:Rest(display_short)|uniprotkb:Nrsf(gene name synonym)|uniprotkb:Neural-restrictive silencer factor(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Hasegawa et al. (2018) imex:IM-28720|pubmed:29320702 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-26604818|imex:IM-28720-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000039410(gene)|ensembl:ENSMUST00000030902(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005829"(cytosol)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0016235"(aggresome)|go:"GO:0017053"(transcription repressor complex)|go:"GO:0019827"(stem cell population maintenance)|go:"GO:0022008"(neurogenesis)|go:"GO:0030512"(negative regulation of transforming growth factor beta receptor signaling pathway)|go:"GO:0030853"(negative regulation of granulocyte differentiation)|go:"GO:0035019"(somatic stem cell population maintenance)|go:"GO:0043457"(regulation of cellular respiration)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0043586"(tongue development)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0046332"(SMAD binding)|go:"GO:0046872"(metal ion binding)|go:"GO:0046974"("histone methyltransferase activity (H3-K9 specific)")|go:"GO:0048468"(cell development)|go:"GO:0050872"(white fat cell differentiation)|go:"GO:0050873"(brown fat cell differentiation)|go:"GO:0060021"(roof of mouth development)|go:"GO:0070828"(heterochromatin organization)|go:"GO:0090336"(positive regulation of brown fat cell differentiation)|go:"GO:0120162"(positive regulation of cold-induced thermogenesis)|go:"GO:0140297"(DNA-binding transcription factor binding)|interpro:IPR001214(SET)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR036236|interpro:IPR044410|mint:A2A935|reactome:R-MMU-3214841|refseq:NP_001277955.1|refseq:NP_001277958.1|refseq:XP_006539236.1|refseq:NP_081780.3|dip:DIP-60593N refseq:XP_006534905.1|refseq:NP_035393.2|ensembl:ENSMUSG00000029249(gene)|ensembl:ENSMUST00000080359(transcript)|ensembl:ENSMUST00000113449(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000381"(regulation of alternative mRNA splicing, via spliceosome)|go:"GO:0000785"(chromatin)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000979"(RNA polymerase II core promoter sequence-specific DNA binding)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0001666"(response to hypoxia)|go:"GO:0002244"(hematopoietic progenitor cell differentiation)|go:"GO:0002931"(response to ischemia)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0017053"(transcription repressor complex)|go:"GO:0032348"(negative regulation of aldosterone biosynthetic process)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035019"(somatic stem cell population maintenance)|go:"GO:0035690"|go:"GO:0042802"(identical protein binding)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043280"(positive regulation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0043922"(negative regulation by host of viral transcription)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045665"(negative regulation of neuron differentiation)|go:"GO:0045666"(positive regulation of neuron differentiation)|go:"GO:0045667"(regulation of osteoblast differentiation)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0045955"(negative regulation of calcium ion-dependent exocytosis)|go:"GO:0046676"(negative regulation of insulin secretion)|go:"GO:0046872"(metal ion binding)|go:"GO:0050768"(negative regulation of neurogenesis)|go:"GO:0050885"(neuromuscular process controlling balance)|go:"GO:0050910"(detection of mechanical stimulus involved in sensory perception of sound)|go:"GO:0060088"(auditory receptor cell stereocilium organization)|go:"GO:0060379"(cardiac muscle cell myoblast differentiation)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:0070933"(histone H4 deacetylation)|go:"GO:0071257"(cellular response to electrical stimulus)|go:"GO:0071385"(cellular response to glucocorticoid stimulus)|go:"GO:0097150"(neuronal stem cell population maintenance)|go:"GO:0099563"(modification of synaptic structure)|go:"GO:1902459"(positive regulation of stem cell population maintenance)|go:"GO:1902894"(negative regulation of miRNA transcription)|go:"GO:1903203"(regulation of oxidative stress-induced neuron death)|go:"GO:1903204"(negative regulation of oxidative stress-induced neuron death)|go:"GO:1903223"(positive regulation of oxidative stress-induced neuron death)|go:"GO:2000065"(negative regulation of cortisol biosynthetic process)|go:"GO:2000678"(negative regulation of transcription regulatory region DNA binding)|go:"GO:2000706"(negative regulation of dense core granule biogenesis)|go:"GO:2000740"(negative regulation of mesenchymal stem cell differentiation)|go:"GO:2000798"(negative regulation of amniotic stem cell differentiation)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR027757|interpro:IPR036236|mint:Q8VIG1|reactome:R-MMU-3214815 go:"GO:0005634"(nucleus) - - figure legend:F2A ST1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-adipocytes)|taxid:10090(Mus musculus) - 2020/12/10 2021/11/30 rogid:IIoKgZ/wtPhFX+h3JHXbeH2HEpg10090 rogid:a2nJenbqqCXCUbKM//5DZQ/hz7I10090 rigid:R7kioghQ/VgGJ/w0NAh+OXuZX6U false flag tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:A2A935 uniprotkb:Q8VHR5 intact:EBI-6268248|ensembl:ENSMUSP00000030902|uniprotkb:Q69ZD6|uniprotkb:Q6PB79|uniprotkb:Q7TPF4 intact:EBI-3043880|ensembl:ENSMUSP00000041370|ensembl:ENSMUSP00000142514|ensembl:ENSMUSP00000142617|uniprotkb:Q8C9Q3 psi-mi:prd16_mouse(display_long)|uniprotkb:PR domain zinc finger protein 16(gene name synonym)|uniprotkb:Prdm16(gene name)|psi-mi:Prdm16(display_short)|uniprotkb:Kiaa1675(gene name synonym)|uniprotkb:Mel1(gene name synonym)|uniprotkb:PR domain-containing protein 16(gene name synonym)|uniprotkb:Transcription factor MEL1(gene name synonym) psi-mi:p66b_mouse(display_long)|uniprotkb:Gatad2b(gene name)|psi-mi:Gatad2b(display_short)|uniprotkb:GATA zinc finger domain-containing protein 2B(gene name synonym)|uniprotkb:p66/p68(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Hasegawa et al. (2018) imex:IM-28720|pubmed:29320702 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-26604818|imex:IM-28720-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000039410(gene)|ensembl:ENSMUST00000030902(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005829"(cytosol)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0016235"(aggresome)|go:"GO:0017053"(transcription repressor complex)|go:"GO:0019827"(stem cell population maintenance)|go:"GO:0022008"(neurogenesis)|go:"GO:0030512"(negative regulation of transforming growth factor beta receptor signaling pathway)|go:"GO:0030853"(negative regulation of granulocyte differentiation)|go:"GO:0035019"(somatic stem cell population maintenance)|go:"GO:0043457"(regulation of cellular respiration)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0043586"(tongue development)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0046332"(SMAD binding)|go:"GO:0046872"(metal ion binding)|go:"GO:0046974"("histone methyltransferase activity (H3-K9 specific)")|go:"GO:0048468"(cell development)|go:"GO:0050872"(white fat cell differentiation)|go:"GO:0050873"(brown fat cell differentiation)|go:"GO:0060021"(roof of mouth development)|go:"GO:0070828"(heterochromatin organization)|go:"GO:0090336"(positive regulation of brown fat cell differentiation)|go:"GO:0120162"(positive regulation of cold-induced thermogenesis)|go:"GO:0140297"(DNA-binding transcription factor binding)|interpro:IPR001214(SET)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR036236|interpro:IPR044410|mint:A2A935|reactome:R-MMU-3214841|refseq:NP_001277955.1|refseq:NP_001277958.1|refseq:XP_006539236.1|refseq:NP_081780.3|dip:DIP-60593N ensembl:ENSMUSG00000042390(gene)|ensembl:ENSMUST00000049382(transcript)|ensembl:ENSMUST00000199607(transcript)|ensembl:ENSMUST00000199754(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0005654"(nucleoplasm)|go:"GO:0008270"(zinc ion binding)|go:"GO:0016581"(NuRD complex)|go:"GO:0016607"(nuclear speck)|go:"GO:0043565"(sequence-specific DNA binding)|interpro:IPR000679(Zinc finger, GATA-type)|interpro:IPR013088(Zinc finger, NHR/GATA-type)|interpro:IPR032346|interpro:IPR040386|reactome:R-MMU-3214815|reactome:R-MMU-6804758|reactome:R-MMU-73762|reactome:R-MMU-8943724|mint:Q8VHR5|refseq:XP_006501422.2|refseq:NP_647465.1|refseq:XP_006501424.1|dip:DIP-62049N go:"GO:0005634"(nucleus) - - figure legend:F2A ST1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-adipocytes)|taxid:10090(Mus musculus) - 2020/12/10 2021/11/30 rogid:IIoKgZ/wtPhFX+h3JHXbeH2HEpg10090 rogid:u6tGN+nqNC/bn1hYG7e1f3XGgj010090 rigid:R7kioghQ/VgGJ/w0NAh+OXuZX6U false flag tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:A2A935 uniprotkb:P02340 intact:EBI-6268248|ensembl:ENSMUSP00000030902|uniprotkb:Q69ZD6|uniprotkb:Q6PB79|uniprotkb:Q7TPF4 intact:EBI-474016|uniprotkb:Q9QUP3|ensembl:ENSMUSP00000104298 psi-mi:prd16_mouse(display_long)|uniprotkb:PR domain zinc finger protein 16(gene name synonym)|uniprotkb:Prdm16(gene name)|psi-mi:Prdm16(display_short)|uniprotkb:Kiaa1675(gene name synonym)|uniprotkb:Mel1(gene name synonym)|uniprotkb:PR domain-containing protein 16(gene name synonym)|uniprotkb:Transcription factor MEL1(gene name synonym) psi-mi:p53_mouse(display_long)|uniprotkb:Tp53(gene name)|psi-mi:Tp53(display_short)|uniprotkb:P53(gene name synonym)|uniprotkb:Trp53(gene name synonym)|uniprotkb:Tumor suppressor p53(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Hasegawa et al. (2018) imex:IM-28720|pubmed:29320702 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-26604818|imex:IM-28720-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000039410(gene)|ensembl:ENSMUST00000030902(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005829"(cytosol)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0016235"(aggresome)|go:"GO:0017053"(transcription repressor complex)|go:"GO:0019827"(stem cell population maintenance)|go:"GO:0022008"(neurogenesis)|go:"GO:0030512"(negative regulation of transforming growth factor beta receptor signaling pathway)|go:"GO:0030853"(negative regulation of granulocyte differentiation)|go:"GO:0035019"(somatic stem cell population maintenance)|go:"GO:0043457"(regulation of cellular respiration)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0043586"(tongue development)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0046332"(SMAD binding)|go:"GO:0046872"(metal ion binding)|go:"GO:0046974"("histone methyltransferase activity (H3-K9 specific)")|go:"GO:0048468"(cell development)|go:"GO:0050872"(white fat cell differentiation)|go:"GO:0050873"(brown fat cell differentiation)|go:"GO:0060021"(roof of mouth development)|go:"GO:0070828"(heterochromatin organization)|go:"GO:0090336"(positive regulation of brown fat cell differentiation)|go:"GO:0120162"(positive regulation of cold-induced thermogenesis)|go:"GO:0140297"(DNA-binding transcription factor binding)|interpro:IPR001214(SET)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR036236|interpro:IPR044410|mint:A2A935|reactome:R-MMU-3214841|refseq:NP_001277955.1|refseq:NP_001277958.1|refseq:XP_006539236.1|refseq:NP_081780.3|dip:DIP-60593N ensembl:ENSMUSG00000059552(gene)|ensembl:ENSMUST00000108658(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0000987"(cis-regulatory region sequence-specific DNA binding)|go:"GO:0001046"(core promoter sequence-specific DNA binding)|go:"GO:0001094"(TFIID-class transcription factor complex binding)|go:"GO:0001216"(DNA-binding transcription activator activity)|go:"GO:0001221"(transcription coregulator binding)|go:"GO:0072331"(signal transduction by p53 class mediator)|go:"GO:0072332"(intrinsic apoptotic signaling pathway by p53 class mediator)|go:"GO:0072717"(cellular response to actinomycin D)|go:"GO:0090200"(positive regulation of release of cytochrome c from mitochondria)|go:"GO:0090343"(positive regulation of cell aging)|go:"GO:0090399"(replicative senescence)|go:"GO:0090403"(oxidative stress-induced premature senescence)|go:"GO:0090575"(RNA polymerase II transcription regulator complex)|go:"GO:0097252"(oligodendrocyte apoptotic process)|go:"GO:0097371"(MDM2/MDM4 family protein binding)|go:"GO:0097718"(disordered domain specific binding)|go:"GO:1900119"(positive regulation of execution phase of apoptosis)|go:"GO:1901525"(negative regulation of mitophagy)|go:"GO:1902108"(regulation of mitochondrial membrane permeability involved in apoptotic process)|go:"GO:1902253"(regulation of intrinsic apoptotic signaling pathway by p53 class mediator)|go:"GO:1902895"(positive regulation of miRNA transcription)|go:"GO:1903205"(regulation of hydrogen peroxide-induced cell death)|go:"GO:1903799"(negative regulation of production of miRNAs involved in gene silencing by miRNA)|go:"GO:1903800"(positive regulation of production of miRNAs involved in gene silencing by miRNA)|go:"GO:1904024"(negative regulation of glucose catabolic process to lactate via pyruvate)|go:"GO:1905856"(negative regulation of pentose-phosphate shunt)|go:"GO:1990144"(intrinsic apoptotic signaling pathway in response to hypoxia)|go:"GO:1990248"(regulation of transcription from RNA polymerase II promoter in response to DNA damage)|go:"GO:1990440"(positive regulation of transcription from RNA polymerase II promoter in response to endoplasmic reticulum stress)|go:"GO:1990841"(promoter-specific chromatin binding)|go:"GO:2000269"(regulation of fibroblast apoptotic process)|go:"GO:2000279"(negative regulation of DNA biosynthetic process)|go:"GO:2000378"(negative regulation of reactive oxygen species metabolic process)|go:"GO:0071494"(cellular response to UV-C)|go:"GO:2000379"(positive regulation of reactive oxygen species metabolic process)|go:"GO:2000772"(regulation of cellular senescence)|go:"GO:2001244"(positive regulation of intrinsic apoptotic signaling pathway)|interpro:IPR002117(p53 tumor antigen)|interpro:IPR008967(p53-like transcription factor, DNA-binding)|interpro:IPR010991(p53, tetramerisation)|interpro:IPR011615(p53, DNA-binding)|interpro:IPR012346(p53 and RUNT-type transcription factor, DNA-binding)|interpro:IPR013872("p53 transactivation domain (TAD)")|interpro:IPR036674|mint:P02340|rcsb pdb:1HU8|rcsb pdb:2GEQ|rcsb pdb:2IOI|rcsb pdb:2IOM|rcsb pdb:2IOO|rcsb pdb:2P52|rcsb pdb:3EXJ|rcsb pdb:3EXL|reactome:R-MMU-2559580|reactome:R-MMU-2559584|reactome:R-MMU-2559585|reactome:R-MMU-2559586|reactome:R-MMU-349425|reactome:R-MMU-5689880|reactome:R-MMU-5689896|reactome:R-MMU-5693565|reactome:R-MMU-6804754|reactome:R-MMU-6804756|reactome:R-MMU-6804757|reactome:R-MMU-6804758|reactome:R-MMU-6804759|reactome:R-MMU-6804760|reactome:R-MMU-6811555|reactome:R-MMU-69473|reactome:R-MMU-69481|reactome:R-MMU-69541|reactome:R-MMU-69895|reactome:R-MMU-8852276|reactome:R-MMU-8941855|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0001756"(somitogenesis)|go:"GO:0001836"(release of cytochrome c from mitochondria)|go:"GO:0002020"(protease binding)|go:"GO:0002039"(p53 binding)|go:"GO:0002244"(hematopoietic progenitor cell differentiation)|go:"GO:0002309"(T cell proliferation involved in immune response)|go:"GO:0002326"(B cell lineage commitment)|go:"GO:0002360"(T cell lineage commitment)|go:"GO:0002687"(positive regulation of leukocyte migration)|go:"GO:0002931"(response to ischemia)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0003730"(mRNA 3'-UTR binding)|go:"GO:0005507"(copper ion binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005657"(replication fork)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0006289"(nucleotide-excision repair)|go:"GO:0006302"(double-strand break repair)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006914"(autophagy)|go:"GO:0006915"(apoptotic process)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0006977"(DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest)|go:"GO:0006978"(DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator)|go:"GO:0006979"(response to oxidative stress)|go:"GO:0006983"(ER overload response)|go:"GO:0007179"(transforming growth factor beta receptor signaling pathway)|go:"GO:0007265"(Ras protein signal transduction)|go:"GO:0007346"(regulation of mitotic cell cycle)|go:"GO:0007369"(gastrulation)|go:"GO:0007406"(negative regulation of neuroblast proliferation)|go:"GO:0007417"(central nervous system development)|go:"GO:0007507"(heart development)|go:"GO:0007569"(cell aging)|go:"GO:0007623"(circadian rhythm)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008104"(protein localization)|go:"GO:0008156"(negative regulation of DNA replication)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0008340"(determination of adult lifespan)|go:"GO:0009299"(mRNA transcription)|go:"GO:0009303"(rRNA transcription)|go:"GO:0009411"(response to UV)|go:"GO:0009651"(response to salt stress)|go:"GO:0009792"(embryo development ending in birth or egg hatching)|go:"GO:0010038"(response to metal ion)|go:"GO:0010165"(response to X-ray)|go:"GO:0010224"(response to UV-B)|go:"GO:0010332"(response to gamma radiation)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0010666"(positive regulation of cardiac muscle cell apoptotic process)|go:"GO:0016032"(viral process)|go:"GO:0016363"(nuclear matrix)|go:"GO:0016605"(PML body)|go:"GO:0019899"(enzyme binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0019903"(protein phosphatase binding)|go:"GO:0021549"(cerebellum development)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0030330"(DNA damage response, signal transduction by p53 class mediator)|go:"GO:0030512"(negative regulation of transforming growth factor beta receptor signaling pathway)|go:"GO:0030971"(receptor tyrosine kinase binding)|go:"GO:0031000"(response to caffeine)|go:"GO:0031065"(positive regulation of histone deacetylation)|go:"GO:0031497"(chromatin assembly)|go:"GO:0031571"(mitotic G1 DNA damage checkpoint signaling)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032526"(response to retinoic acid)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033077"(T cell differentiation in thymus)|go:"GO:0033209"(tumor necrosis factor-mediated signaling pathway)|go:"GO:0033552"(response to vitamin B3)|go:"GO:0034103"(regulation of tissue remodeling)|go:"GO:0034605"(cellular response to heat)|go:"GO:0034613"(cellular protein localization)|go:"GO:0034614"(cellular response to reactive oxygen species)|go:"GO:0035033"(histone deacetylase regulator activity)|go:"GO:0035035"(histone acetyltransferase binding)|go:"GO:0035264"(multicellular organism growth)|go:"GO:0035690"|go:"GO:0035794"(positive regulation of mitochondrial membrane permeability)|go:"GO:0035861"(site of double-strand break)|go:"GO:0036003"(positive regulation of transcription from RNA polymerase II promoter in response to stress)|go:"GO:0036310"(ATP-dependent DNA/DNA annealing activity)|go:"GO:0042060"(wound healing)|go:"GO:0042127"(regulation of cell population proliferation)|go:"GO:0042149"(cellular response to glucose starvation)|go:"GO:0042493"|go:"GO:0042771"(intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator)|go:"GO:0042802"(identical protein binding)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043153"(entrainment of circadian clock by photoperiod)|go:"GO:0043200"(response to amino acid)|go:"GO:0043504"(mitochondrial DNA repair)|go:"GO:0043516"(regulation of DNA damage response, signal transduction by p53 class mediator)|go:"GO:0043523"(regulation of neuron apoptotic process)|go:"GO:0043525"(positive regulation of neuron apoptotic process)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0043621"(protein self-association)|go:"GO:0045471"(response to ethanol)|go:"GO:0045787"(positive regulation of cell cycle)|go:"GO:0045861"(negative regulation of proteolysis)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045899"(positive regulation of RNA polymerase II transcription preinitiation complex assembly)|go:"GO:0045930"(negative regulation of mitotic cell cycle)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0047485"(protein N-terminus binding)|go:"GO:0048147"(negative regulation of fibroblast proliferation)|go:"GO:0048512"(circadian behavior)|go:"GO:0048539"(bone marrow development)|go:"GO:0048568"(embryonic organ development)|go:"GO:0048662"(negative regulation of smooth muscle cell proliferation)|go:"GO:0050731"(positive regulation of peptidyl-tyrosine phosphorylation)|go:"GO:0050821"(protein stabilization)|go:"GO:0051087"(chaperone binding)|go:"GO:0051262"(protein tetramerization)|go:"GO:0051276"(chromosome organization)|go:"GO:0051402"(neuron apoptotic process)|go:"GO:0051453"(regulation of intracellular pH)|go:"GO:0051721"(protein phosphatase 2A binding)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0051974"(negative regulation of telomerase activity)|go:"GO:0055093"(response to hyperoxia)|go:"GO:0060218"(hematopoietic stem cell differentiation)|go:"GO:0060333"(interferon-gamma-mediated signaling pathway)|go:"GO:0060411"(cardiac septum morphogenesis)|go:"GO:0061419"(positive regulation of transcription from RNA polymerase II promoter in response to hypoxia)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:0062100"(positive regulation of programmed necrotic cell death)|go:"GO:0065003"(protein-containing complex assembly)|go:"GO:0070059"(intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress)|go:"GO:0070243"(regulation of thymocyte apoptotic process)|go:"GO:0070245"(positive regulation of thymocyte apoptotic process)|go:"GO:0070266"(necroptotic process)|go:"GO:0071479"(cellular response to ionizing radiation)|go:"GO:0071480"(cellular response to gamma radiation)|go:"GO:0034644"(cellular response to UV)|refseq:NP_001120705.1|refseq:NP_035770.2|refseq:XP_006533220.1|dip:DIP-369N go:"GO:0005634"(nucleus) - - figure legend:F2A ST1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-adipocytes)|taxid:10090(Mus musculus) - 2020/12/10 2021/11/30 rogid:IIoKgZ/wtPhFX+h3JHXbeH2HEpg10090 rogid:ZU1071LBVm95uqzi6RBNluw8wFo10090 rigid:R7kioghQ/VgGJ/w0NAh+OXuZX6U false flag tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:A2A935 uniprotkb:Q8CBD1 intact:EBI-6268248|ensembl:ENSMUSP00000030902|uniprotkb:Q69ZD6|uniprotkb:Q6PB79|uniprotkb:Q7TPF4 intact:EBI-1771626|uniprotkb:Q3U166|uniprotkb:Q8C3Y8|uniprotkb:Q9Z2K2|ensembl:ENSMUSP00000051726|ensembl:ENSMUSP00000112959 psi-mi:prd16_mouse(display_long)|uniprotkb:PR domain zinc finger protein 16(gene name synonym)|uniprotkb:Prdm16(gene name)|psi-mi:Prdm16(display_short)|uniprotkb:Kiaa1675(gene name synonym)|uniprotkb:Mel1(gene name synonym)|uniprotkb:PR domain-containing protein 16(gene name synonym)|uniprotkb:Transcription factor MEL1(gene name synonym) psi-mi:nrip1_mouse(display_long)|uniprotkb:Nrip1(gene name)|psi-mi:Nrip1(display_short)|uniprotkb:Nuclear factor RIP140(gene name synonym)|uniprotkb:Receptor-interacting protein 140(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Hasegawa et al. (2018) imex:IM-28720|pubmed:29320702 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-26604818|imex:IM-28720-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000039410(gene)|ensembl:ENSMUST00000030902(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005829"(cytosol)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0016235"(aggresome)|go:"GO:0017053"(transcription repressor complex)|go:"GO:0019827"(stem cell population maintenance)|go:"GO:0022008"(neurogenesis)|go:"GO:0030512"(negative regulation of transforming growth factor beta receptor signaling pathway)|go:"GO:0030853"(negative regulation of granulocyte differentiation)|go:"GO:0035019"(somatic stem cell population maintenance)|go:"GO:0043457"(regulation of cellular respiration)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0043586"(tongue development)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0046332"(SMAD binding)|go:"GO:0046872"(metal ion binding)|go:"GO:0046974"("histone methyltransferase activity (H3-K9 specific)")|go:"GO:0048468"(cell development)|go:"GO:0050872"(white fat cell differentiation)|go:"GO:0050873"(brown fat cell differentiation)|go:"GO:0060021"(roof of mouth development)|go:"GO:0070828"(heterochromatin organization)|go:"GO:0090336"(positive regulation of brown fat cell differentiation)|go:"GO:0120162"(positive regulation of cold-induced thermogenesis)|go:"GO:0140297"(DNA-binding transcription factor binding)|interpro:IPR001214(SET)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR036236|interpro:IPR044410|mint:A2A935|reactome:R-MMU-3214841|refseq:NP_001277955.1|refseq:NP_001277958.1|refseq:XP_006539236.1|refseq:NP_081780.3|dip:DIP-60593N refseq:NP_775616.1|refseq:XP_006523117.1|refseq:XP_006523113.1|refseq:XP_006523114.1|refseq:XP_017172509.1|dip:DIP-29280N|ensembl:ENSMUSG00000048490(gene)|ensembl:ENSMUST00000054178(transcript)|ensembl:ENSMUST00000121927(transcript)|go:"GO:0000118"(histone deacetylase complex)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0001543"(ovarian follicle rupture)|go:"GO:0001650"(fibrillar center)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0016607"(nuclear speck)|go:"GO:0016922"(nuclear receptor binding)|go:"GO:0019915"(lipid storage)|go:"GO:0030331"(estrogen receptor binding)|go:"GO:0030728"(ovulation)|go:"GO:0032922"(circadian regulation of gene expression)|go:"GO:0035259"(glucocorticoid receptor binding)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0042974"(retinoic acid receptor binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046965"(retinoid X receptor binding)|go:"GO:0071392"(cellular response to estradiol stimulus)|interpro:IPR026649|interpro:IPR031405|interpro:IPR031406|interpro:IPR031407|interpro:IPR031408|mint:Q8CBD1|reactome:R-MMU-3899300|reactome:R-MMU-9018519 go:"GO:0005634"(nucleus) - - figure legend:F2A ST1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-adipocytes)|taxid:10090(Mus musculus) - 2020/12/10 2021/11/30 rogid:IIoKgZ/wtPhFX+h3JHXbeH2HEpg10090 rogid:XdKG14YpCI6JqIQr5MQ0uoXvfss10090 rigid:R7kioghQ/VgGJ/w0NAh+OXuZX6U false flag tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:A2A935 uniprotkb:P70257 intact:EBI-6268248|ensembl:ENSMUSP00000030902|uniprotkb:Q69ZD6|uniprotkb:Q6PB79|uniprotkb:Q7TPF4 intact:EBI-2639047|uniprotkb:O08519|uniprotkb:P70258|uniprotkb:Q64192|uniprotkb:Q99L78|uniprotkb:Q9R1G2 psi-mi:prd16_mouse(display_long)|uniprotkb:PR domain zinc finger protein 16(gene name synonym)|uniprotkb:Prdm16(gene name)|psi-mi:Prdm16(display_short)|uniprotkb:Kiaa1675(gene name synonym)|uniprotkb:Mel1(gene name synonym)|uniprotkb:PR domain-containing protein 16(gene name synonym)|uniprotkb:Transcription factor MEL1(gene name synonym) psi-mi:nfix_mouse(display_long)|uniprotkb:Nfix(gene name)|psi-mi:Nfix(display_short)|uniprotkb:Nuclear factor I/X(gene name synonym)|uniprotkb:CCAAT-box-binding transcription factor(gene name synonym)|uniprotkb:TGGCA-binding protein(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Hasegawa et al. (2018) imex:IM-28720|pubmed:29320702 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-26604818|imex:IM-28720-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000039410(gene)|ensembl:ENSMUST00000030902(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005829"(cytosol)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0016235"(aggresome)|go:"GO:0017053"(transcription repressor complex)|go:"GO:0019827"(stem cell population maintenance)|go:"GO:0022008"(neurogenesis)|go:"GO:0030512"(negative regulation of transforming growth factor beta receptor signaling pathway)|go:"GO:0030853"(negative regulation of granulocyte differentiation)|go:"GO:0035019"(somatic stem cell population maintenance)|go:"GO:0043457"(regulation of cellular respiration)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0043586"(tongue development)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0046332"(SMAD binding)|go:"GO:0046872"(metal ion binding)|go:"GO:0046974"("histone methyltransferase activity (H3-K9 specific)")|go:"GO:0048468"(cell development)|go:"GO:0050872"(white fat cell differentiation)|go:"GO:0050873"(brown fat cell differentiation)|go:"GO:0060021"(roof of mouth development)|go:"GO:0070828"(heterochromatin organization)|go:"GO:0090336"(positive regulation of brown fat cell differentiation)|go:"GO:0120162"(positive regulation of cold-induced thermogenesis)|go:"GO:0140297"(DNA-binding transcription factor binding)|interpro:IPR001214(SET)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR036236|interpro:IPR044410|mint:A2A935|reactome:R-MMU-3214841|refseq:NP_001277955.1|refseq:NP_001277958.1|refseq:XP_006539236.1|refseq:NP_081780.3|dip:DIP-60593N refseq:NP_001075451.1|refseq:NP_035036.1|interpro:IPR000647(CTF/NF-I)|interpro:IPR020604|interpro:IPR019739|interpro:IPR019548|interpro:IPR003619(MAD homology 1, Dwarfin-type)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0005634"(nucleus)|go:"GO:0006260"(DNA replication)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0021549"(cerebellum development)|go:"GO:0021680"(cerebellar Purkinje cell layer development)|go:"GO:0021707"(cerebellar granule cell differentiation)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048708"(astrocyte differentiation)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|mint:P70257 go:"GO:0005634"(nucleus) - - figure legend:F2A ST1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-adipocytes)|taxid:10090(Mus musculus) - 2020/12/10 2021/11/30 rogid:IIoKgZ/wtPhFX+h3JHXbeH2HEpg10090 rogid:5TGzlF8pDJ85EBsxigizYV1O7U010090 rigid:R7kioghQ/VgGJ/w0NAh+OXuZX6U false flag tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:A2A935 uniprotkb:O08750 intact:EBI-6268248|ensembl:ENSMUSP00000030902|uniprotkb:Q69ZD6|uniprotkb:Q6PB79|uniprotkb:Q7TPF4 intact:EBI-11424699|uniprotkb:Q3ULK2|uniprotkb:Q497U0|ensembl:ENSMUSP00000065363 psi-mi:prd16_mouse(display_long)|uniprotkb:PR domain zinc finger protein 16(gene name synonym)|uniprotkb:Prdm16(gene name)|psi-mi:Prdm16(display_short)|uniprotkb:Kiaa1675(gene name synonym)|uniprotkb:Mel1(gene name synonym)|uniprotkb:PR domain-containing protein 16(gene name synonym)|uniprotkb:Transcription factor MEL1(gene name synonym) psi-mi:nfil3_mouse(display_long)|uniprotkb:Nfil3(gene name)|psi-mi:Nfil3(display_short)|uniprotkb:E4bp4(gene name synonym)|uniprotkb:E4 promoter-binding protein 4(gene name synonym)|uniprotkb:Embryo implantation-related NFIL3/E4BP4-like transcription factor(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Hasegawa et al. (2018) imex:IM-28720|pubmed:29320702 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-26604818|imex:IM-28720-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000039410(gene)|ensembl:ENSMUST00000030902(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005829"(cytosol)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0016235"(aggresome)|go:"GO:0017053"(transcription repressor complex)|go:"GO:0019827"(stem cell population maintenance)|go:"GO:0022008"(neurogenesis)|go:"GO:0030512"(negative regulation of transforming growth factor beta receptor signaling pathway)|go:"GO:0030853"(negative regulation of granulocyte differentiation)|go:"GO:0035019"(somatic stem cell population maintenance)|go:"GO:0043457"(regulation of cellular respiration)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0043586"(tongue development)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0046332"(SMAD binding)|go:"GO:0046872"(metal ion binding)|go:"GO:0046974"("histone methyltransferase activity (H3-K9 specific)")|go:"GO:0048468"(cell development)|go:"GO:0050872"(white fat cell differentiation)|go:"GO:0050873"(brown fat cell differentiation)|go:"GO:0060021"(roof of mouth development)|go:"GO:0070828"(heterochromatin organization)|go:"GO:0090336"(positive regulation of brown fat cell differentiation)|go:"GO:0120162"(positive regulation of cold-induced thermogenesis)|go:"GO:0140297"(DNA-binding transcription factor binding)|interpro:IPR001214(SET)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR036236|interpro:IPR044410|mint:A2A935|reactome:R-MMU-3214841|refseq:NP_001277955.1|refseq:NP_001277958.1|refseq:XP_006539236.1|refseq:NP_081780.3|dip:DIP-60593N refseq:NP_059069.1|refseq:XP_006516940.1|refseq:XP_011242681.1|ensembl:ENSMUSG00000056749(gene)|ensembl:ENSMUST00000071065(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0001779"(natural killer cell differentiation)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0006955"(immune response)|go:"GO:0007623"(circadian rhythm)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0042802"(identical protein binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0071353"(cellular response to interleukin-4)|interpro:IPR004827("Basic-leucine zipper (bZIP) transcription factor")|interpro:IPR010533(Vertebrate interleukin-3 regulated transcription factor)|interpro:IPR016743(Transcription factor, basic leucine zipper, E4BP4)|mint:O08750|refseq:XP_017170907.1 go:"GO:0005634"(nucleus) - - figure legend:F2A ST1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-adipocytes)|taxid:10090(Mus musculus) - 2020/12/10 2021/11/30 rogid:IIoKgZ/wtPhFX+h3JHXbeH2HEpg10090 rogid:0QQb7os33Vd+ZOrY/eQPqkES7cQ10090 rigid:R7kioghQ/VgGJ/w0NAh+OXuZX6U false flag tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:A2A935 uniprotkb:P97863 intact:EBI-6268248|ensembl:ENSMUSP00000030902|uniprotkb:Q69ZD6|uniprotkb:Q6PB79|uniprotkb:Q7TPF4 intact:EBI-6122967|uniprotkb:P70252|uniprotkb:P70253|uniprotkb:P70254|uniprotkb:Q9R1G4|ensembl:ENSMUSP00000052863 psi-mi:prd16_mouse(display_long)|uniprotkb:PR domain zinc finger protein 16(gene name synonym)|uniprotkb:Prdm16(gene name)|psi-mi:Prdm16(display_short)|uniprotkb:Kiaa1675(gene name synonym)|uniprotkb:Mel1(gene name synonym)|uniprotkb:PR domain-containing protein 16(gene name synonym)|uniprotkb:Transcription factor MEL1(gene name synonym) psi-mi:nfib_mouse(display_long)|uniprotkb:Nfib(gene name)|psi-mi:Nfib(display_short)|uniprotkb:CCAAT-box-binding transcription factor(gene name synonym)|uniprotkb:Nuclear factor I/B(gene name synonym)|uniprotkb:TGGCA-binding protein(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Hasegawa et al. (2018) imex:IM-28720|pubmed:29320702 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-26604818|imex:IM-28720-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000039410(gene)|ensembl:ENSMUST00000030902(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005829"(cytosol)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0016235"(aggresome)|go:"GO:0017053"(transcription repressor complex)|go:"GO:0019827"(stem cell population maintenance)|go:"GO:0022008"(neurogenesis)|go:"GO:0030512"(negative regulation of transforming growth factor beta receptor signaling pathway)|go:"GO:0030853"(negative regulation of granulocyte differentiation)|go:"GO:0035019"(somatic stem cell population maintenance)|go:"GO:0043457"(regulation of cellular respiration)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0043586"(tongue development)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0046332"(SMAD binding)|go:"GO:0046872"(metal ion binding)|go:"GO:0046974"("histone methyltransferase activity (H3-K9 specific)")|go:"GO:0048468"(cell development)|go:"GO:0050872"(white fat cell differentiation)|go:"GO:0050873"(brown fat cell differentiation)|go:"GO:0060021"(roof of mouth development)|go:"GO:0070828"(heterochromatin organization)|go:"GO:0090336"(positive regulation of brown fat cell differentiation)|go:"GO:0120162"(positive regulation of cold-induced thermogenesis)|go:"GO:0140297"(DNA-binding transcription factor binding)|interpro:IPR001214(SET)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR036236|interpro:IPR044410|mint:A2A935|reactome:R-MMU-3214841|refseq:NP_001277955.1|refseq:NP_001277958.1|refseq:XP_006539236.1|refseq:NP_081780.3|dip:DIP-60593N refseq:NP_001106680.1|refseq:NP_032713.3|ensembl:ENSMUSG00000008575(gene)|ensembl:ENSMUST00000050872(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0002062"(chondrocyte differentiation)|go:"GO:0003677"(DNA binding)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006260"(DNA replication)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007420"(brain development)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0009617"(response to bacterium)|go:"GO:0010001"(glial cell differentiation)|go:"GO:0021740"(principal sensory nucleus of trigeminal nerve development)|go:"GO:0021960"(anterior commissure morphogenesis)|go:"GO:0030324"(lung development)|go:"GO:0030900"(forebrain development)|go:"GO:0030902"(hindbrain development)|go:"GO:0043392"(negative regulation of DNA binding)|go:"GO:0044300"(cerebellar mossy fiber)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0060486"(club cell differentiation)|go:"GO:0060509"(type I pneumocyte differentiation)|go:"GO:0060510"(type II pneumocyte differentiation)|go:"GO:0060662"(salivary gland cavitation)|go:"GO:0060689"(cell differentiation involved in salivary gland development)|go:"GO:0061141"(lung ciliated cell differentiation)|go:"GO:0071679"(commissural neuron axon guidance)|go:"GO:0140416"(transcription regulator inhibitor activity)|go:"GO:1902894"(negative regulation of miRNA transcription)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|go:"GO:2000791"(negative regulation of mesenchymal cell proliferation involved in lung development)|go:"GO:2000795"(negative regulation of epithelial cell proliferation involved in lung morphogenesis)|interpro:IPR000647(CTF/NF-I)|interpro:IPR003619(MAD homology 1, Dwarfin-type)|interpro:IPR019548|interpro:IPR019739|interpro:IPR020604|mint:P97863|go:"GO:0001650"(fibrillar center) go:"GO:0005634"(nucleus) - - figure legend:F2A ST1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-adipocytes)|taxid:10090(Mus musculus) - 2020/12/10 2021/11/30 rogid:IIoKgZ/wtPhFX+h3JHXbeH2HEpg10090 rogid:q+27AZuN224n0dbYoogA7/JIZ7g10090 rigid:R7kioghQ/VgGJ/w0NAh+OXuZX6U false flag tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:A2A935 uniprotkb:Q9WV30 intact:EBI-6268248|ensembl:ENSMUSP00000030902|uniprotkb:Q69ZD6|uniprotkb:Q6PB79|uniprotkb:Q7TPF4 intact:EBI-26472334|ensembl:ENSMUSP00000116094|uniprotkb:E9Q0P3|uniprotkb:E9Q6U2|uniprotkb:G5E8N9|uniprotkb:Q91WY0|uniprotkb:Q9JLA1 psi-mi:prd16_mouse(display_long)|uniprotkb:PR domain zinc finger protein 16(gene name synonym)|uniprotkb:Prdm16(gene name)|psi-mi:Prdm16(display_short)|uniprotkb:Kiaa1675(gene name synonym)|uniprotkb:Mel1(gene name synonym)|uniprotkb:PR domain-containing protein 16(gene name synonym)|uniprotkb:Transcription factor MEL1(gene name synonym) psi-mi:nfat5_mouse(display_long)|uniprotkb:Nfat5(gene name)|psi-mi:Nfat5(display_short)|uniprotkb:Rel domain-containing transcription factor NFAT5(gene name synonym)|uniprotkb:T-cell transcription factor NFAT5(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Hasegawa et al. (2018) imex:IM-28720|pubmed:29320702 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-26604818|imex:IM-28720-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000039410(gene)|ensembl:ENSMUST00000030902(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005829"(cytosol)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0016235"(aggresome)|go:"GO:0017053"(transcription repressor complex)|go:"GO:0019827"(stem cell population maintenance)|go:"GO:0022008"(neurogenesis)|go:"GO:0030512"(negative regulation of transforming growth factor beta receptor signaling pathway)|go:"GO:0030853"(negative regulation of granulocyte differentiation)|go:"GO:0035019"(somatic stem cell population maintenance)|go:"GO:0043457"(regulation of cellular respiration)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0043586"(tongue development)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0046332"(SMAD binding)|go:"GO:0046872"(metal ion binding)|go:"GO:0046974"("histone methyltransferase activity (H3-K9 specific)")|go:"GO:0048468"(cell development)|go:"GO:0050872"(white fat cell differentiation)|go:"GO:0050873"(brown fat cell differentiation)|go:"GO:0060021"(roof of mouth development)|go:"GO:0070828"(heterochromatin organization)|go:"GO:0090336"(positive regulation of brown fat cell differentiation)|go:"GO:0120162"(positive regulation of cold-induced thermogenesis)|go:"GO:0140297"(DNA-binding transcription factor binding)|interpro:IPR001214(SET)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR036236|interpro:IPR044410|mint:A2A935|reactome:R-MMU-3214841|refseq:NP_001277955.1|refseq:NP_001277958.1|refseq:XP_006539236.1|refseq:NP_081780.3|dip:DIP-60593N ensembl:ENSMUSG00000003847(gene)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0006970"(response to osmotic stress)|go:"GO:0010628"(positive regulation of gene expression)|ensembl:ENSMUST00000125721(transcript)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0033173"(calcineurin-NFAT signaling cascade)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0070884"(regulation of calcineurin-NFAT signaling cascade)|go:"GO:0071345"(cellular response to cytokine stimulus)|go:"GO:1901224"(positive regulation of NIK/NF-kappaB signaling)|go:"GO:1904996"(positive regulation of leukocyte adhesion to vascular endothelial cell)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|interpro:IPR002909(Cell surface receptor IPT/TIG)|interpro:IPR008366("Nuclear factor of activated T cells (NFAT)")|interpro:IPR008967(p53-like transcription factor, DNA-binding)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|interpro:IPR011539(Rel homology)|go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|interpro:IPR013783(Immunoglobulin-like fold)|go:"GO:0005634"(nucleus)|interpro:IPR014756(Immunoglobulin E-set)|go:"GO:0005654"(nucleoplasm)|interpro:IPR015646(Nuclear factor of activated T-cells 5)|interpro:IPR032397|interpro:IPR037059|mint:Q9WV30|refseq:NP_001273189.1|refseq:NP_061293.2|refseq:NP_598718.2|refseq:XP_006531255.1|refseq:XP_017168393.1 go:"GO:0005634"(nucleus) - - figure legend:F2A ST1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-adipocytes)|taxid:10090(Mus musculus) - 2020/12/10 2021/11/30 rogid:IIoKgZ/wtPhFX+h3JHXbeH2HEpg10090 rogid:Yf1n8cmeTkVMCL5aw+LQZwrAIcM10090 rigid:R7kioghQ/VgGJ/w0NAh+OXuZX6U false flag tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:A2A935 uniprotkb:Q8BN78 intact:EBI-6268248|ensembl:ENSMUSP00000030902|uniprotkb:Q69ZD6|uniprotkb:Q6PB79|uniprotkb:Q7TPF4 intact:EBI-1216314|uniprotkb:Q8C226|uniprotkb:Q9WTZ7|ensembl:ENSMUSP00000049983|ensembl:ENSMUSP00000110795 psi-mi:prd16_mouse(display_long)|uniprotkb:PR domain zinc finger protein 16(gene name synonym)|uniprotkb:Prdm16(gene name)|psi-mi:Prdm16(display_short)|uniprotkb:Kiaa1675(gene name synonym)|uniprotkb:Mel1(gene name synonym)|uniprotkb:PR domain-containing protein 16(gene name synonym)|uniprotkb:Transcription factor MEL1(gene name synonym) psi-mi:kaiso_mouse(display_long)|uniprotkb:Zbtb33(gene name)|psi-mi:Zbtb33(display_short)|uniprotkb:Kaiso(gene name synonym)|uniprotkb:Zinc finger and BTB domain-containing protein 33(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Hasegawa et al. (2018) imex:IM-28720|pubmed:29320702 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-26604818|imex:IM-28720-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000039410(gene)|ensembl:ENSMUST00000030902(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005829"(cytosol)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0016235"(aggresome)|go:"GO:0017053"(transcription repressor complex)|go:"GO:0019827"(stem cell population maintenance)|go:"GO:0022008"(neurogenesis)|go:"GO:0030512"(negative regulation of transforming growth factor beta receptor signaling pathway)|go:"GO:0030853"(negative regulation of granulocyte differentiation)|go:"GO:0035019"(somatic stem cell population maintenance)|go:"GO:0043457"(regulation of cellular respiration)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0043586"(tongue development)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0046332"(SMAD binding)|go:"GO:0046872"(metal ion binding)|go:"GO:0046974"("histone methyltransferase activity (H3-K9 specific)")|go:"GO:0048468"(cell development)|go:"GO:0050872"(white fat cell differentiation)|go:"GO:0050873"(brown fat cell differentiation)|go:"GO:0060021"(roof of mouth development)|go:"GO:0070828"(heterochromatin organization)|go:"GO:0090336"(positive regulation of brown fat cell differentiation)|go:"GO:0120162"(positive regulation of cold-induced thermogenesis)|go:"GO:0140297"(DNA-binding transcription factor binding)|interpro:IPR001214(SET)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR036236|interpro:IPR044410|mint:A2A935|reactome:R-MMU-3214841|refseq:NP_001277955.1|refseq:NP_001277958.1|refseq:XP_006539236.1|refseq:NP_081780.3|dip:DIP-60593N refseq:NP_001072981.1|refseq:NP_064652.2|ensembl:ENSMUSG00000048047(gene)|ensembl:ENSMUST00000049740(transcript)|ensembl:ENSMUST00000115142(transcript)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0008327"(methyl-CpG binding)|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0046872"(metal ion binding)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR000210(BTB/POZ-like)|interpro:IPR011333(BTB/POZ fold)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR036236|mint:Q8BN78 go:"GO:0005634"(nucleus) - - figure legend:F2A ST1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-adipocytes)|taxid:10090(Mus musculus) - 2020/12/10 2021/11/30 rogid:IIoKgZ/wtPhFX+h3JHXbeH2HEpg10090 rogid:utdICzKnyrwjxmm96EyYNpiHwv010090 rigid:R7kioghQ/VgGJ/w0NAh+OXuZX6U false flag tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:A2A935 uniprotkb:Q9JI57 intact:EBI-6268248|ensembl:ENSMUSP00000030902|uniprotkb:Q69ZD6|uniprotkb:Q6PB79|uniprotkb:Q7TPF4 intact:EBI-9673183|uniprotkb:Q547E0|uniprotkb:Q80WJ8|uniprotkb:Q80WJ9|uniprotkb:Q80WK0|uniprotkb:Q80WK1|uniprotkb:Q8R4X5|uniprotkb:Q8R4X6|uniprotkb:Q8R4X7|uniprotkb:Q8R4X8|uniprotkb:Q8VHD5|uniprotkb:Q8VI58|uniprotkb:Q9EQE7|uniprotkb:Q9ESZ6|uniprotkb:Q9ESZ7|ensembl:ENSMUSP00000098217 psi-mi:prd16_mouse(display_long)|uniprotkb:PR domain zinc finger protein 16(gene name synonym)|uniprotkb:Prdm16(gene name)|psi-mi:Prdm16(display_short)|uniprotkb:Kiaa1675(gene name synonym)|uniprotkb:Mel1(gene name synonym)|uniprotkb:PR domain-containing protein 16(gene name synonym)|uniprotkb:Transcription factor MEL1(gene name synonym) psi-mi:gt2d1_mouse(display_long)|uniprotkb:Gtf2ird1(gene name)|psi-mi:Gtf2ird1(display_short)|uniprotkb:Ben(gene name synonym)|uniprotkb:Binding factor for early enhancer(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Hasegawa et al. (2018) imex:IM-28720|pubmed:29320702 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-26604818|imex:IM-28720-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000039410(gene)|ensembl:ENSMUST00000030902(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005829"(cytosol)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0016235"(aggresome)|go:"GO:0017053"(transcription repressor complex)|go:"GO:0019827"(stem cell population maintenance)|go:"GO:0022008"(neurogenesis)|go:"GO:0030512"(negative regulation of transforming growth factor beta receptor signaling pathway)|go:"GO:0030853"(negative regulation of granulocyte differentiation)|go:"GO:0035019"(somatic stem cell population maintenance)|go:"GO:0043457"(regulation of cellular respiration)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0043586"(tongue development)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0046332"(SMAD binding)|go:"GO:0046872"(metal ion binding)|go:"GO:0046974"("histone methyltransferase activity (H3-K9 specific)")|go:"GO:0048468"(cell development)|go:"GO:0050872"(white fat cell differentiation)|go:"GO:0050873"(brown fat cell differentiation)|go:"GO:0060021"(roof of mouth development)|go:"GO:0070828"(heterochromatin organization)|go:"GO:0090336"(positive regulation of brown fat cell differentiation)|go:"GO:0120162"(positive regulation of cold-induced thermogenesis)|go:"GO:0140297"(DNA-binding transcription factor binding)|interpro:IPR001214(SET)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR036236|interpro:IPR044410|mint:A2A935|reactome:R-MMU-3214841|refseq:NP_001277955.1|refseq:NP_001277958.1|refseq:XP_006539236.1|refseq:NP_081780.3|dip:DIP-60593N refseq:NP_001334417.1|refseq:XP_017176527.1|refseq:XP_017176528.1|refseq:NP_001074931.1|refseq:NP_001074932.1|refseq:NP_001074935.1|refseq:NP_001074936.1|refseq:NP_001074938.1|refseq:NP_001074939.1|refseq:NP_001231865.1|refseq:NP_065064.2|ensembl:ENSMUSG00000023079(gene)|ensembl:ENSMUST00000100652(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0014886"(transition between slow and fast fiber)|interpro:IPR004212(GTF2I-like repeat)|interpro:IPR016659(Transcription factor II-I)|interpro:IPR036647|mint:Q9JI57 go:"GO:0005634"(nucleus) - - figure legend:F2A ST1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-adipocytes)|taxid:10090(Mus musculus) - 2020/12/10 2021/11/30 rogid:IIoKgZ/wtPhFX+h3JHXbeH2HEpg10090 rogid:FuFR0UjN0B9NGFRRIIF56yYOHbw10090 rigid:R7kioghQ/VgGJ/w0NAh+OXuZX6U false flag tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:A2A935 uniprotkb:P42128 intact:EBI-6268248|ensembl:ENSMUSP00000030902|uniprotkb:Q69ZD6|uniprotkb:Q6PB79|uniprotkb:Q7TPF4 intact:EBI-878270|ensembl:ENSMUSP00000072616|uniprotkb:O35939|uniprotkb:Q3UHI6|uniprotkb:Q3UN67|intact:EBI-878281|intact:EBI-878285 psi-mi:prd16_mouse(display_long)|uniprotkb:PR domain zinc finger protein 16(gene name synonym)|uniprotkb:Prdm16(gene name)|psi-mi:Prdm16(display_short)|uniprotkb:Kiaa1675(gene name synonym)|uniprotkb:Mel1(gene name synonym)|uniprotkb:PR domain-containing protein 16(gene name synonym)|uniprotkb:Transcription factor MEL1(gene name synonym) psi-mi:foxk1_mouse(display_long)|uniprotkb:Myocyte nuclear factor(gene name synonym)|uniprotkb:Foxk1(gene name)|psi-mi:Foxk1(display_short)|uniprotkb:Mnf(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Hasegawa et al. (2018) imex:IM-28720|pubmed:29320702 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-26604818|imex:IM-28720-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000039410(gene)|ensembl:ENSMUST00000030902(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005829"(cytosol)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0016235"(aggresome)|go:"GO:0017053"(transcription repressor complex)|go:"GO:0019827"(stem cell population maintenance)|go:"GO:0022008"(neurogenesis)|go:"GO:0030512"(negative regulation of transforming growth factor beta receptor signaling pathway)|go:"GO:0030853"(negative regulation of granulocyte differentiation)|go:"GO:0035019"(somatic stem cell population maintenance)|go:"GO:0043457"(regulation of cellular respiration)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0043586"(tongue development)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0046332"(SMAD binding)|go:"GO:0046872"(metal ion binding)|go:"GO:0046974"("histone methyltransferase activity (H3-K9 specific)")|go:"GO:0048468"(cell development)|go:"GO:0050872"(white fat cell differentiation)|go:"GO:0050873"(brown fat cell differentiation)|go:"GO:0060021"(roof of mouth development)|go:"GO:0070828"(heterochromatin organization)|go:"GO:0090336"(positive regulation of brown fat cell differentiation)|go:"GO:0120162"(positive regulation of cold-induced thermogenesis)|go:"GO:0140297"(DNA-binding transcription factor binding)|interpro:IPR001214(SET)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR036236|interpro:IPR044410|mint:A2A935|reactome:R-MMU-3214841|refseq:NP_001277955.1|refseq:NP_001277958.1|refseq:XP_006539236.1|refseq:NP_081780.3|dip:DIP-60593N go:"GO:0071889"(14-3-3 protein binding)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR000253(Forkhead-associated)|interpro:IPR001766(Fork head transcription factor)|interpro:IPR008984(SMAD/FHA domain)|interpro:IPR018122|interpro:IPR030456|interpro:IPR036388|interpro:IPR036390|mint:P42128|rcsb pdb:2A3S|rcsb pdb:2D2W|reactome:R-MMU-5689603|ensembl:ENSMUSG00000056493(gene)|ensembl:ENSMUST00000072837(transcript)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0001678"(cellular glucose homeostasis)|go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007517"(muscle organ development)|go:"GO:0010507"(negative regulation of autophagy)|go:"GO:0010906"(regulation of glucose metabolic process)|go:"GO:0030154"(cell differentiation)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0042594"(response to starvation)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045786"(negative regulation of cell cycle)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0061621"(canonical glycolysis)|refseq:NP_951031.2 go:"GO:0005634"(nucleus) - - figure legend:F2A ST1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-adipocytes)|taxid:10090(Mus musculus) - 2020/12/10 2021/11/30 rogid:IIoKgZ/wtPhFX+h3JHXbeH2HEpg10090 rogid:Qg0U+L6F8S2YtysT17gwxkHdyJo10090 rigid:R7kioghQ/VgGJ/w0NAh+OXuZX6U false flag tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:A2A935 uniprotkb:Q61572 intact:EBI-6268248|ensembl:ENSMUSP00000030902|uniprotkb:Q69ZD6|uniprotkb:Q6PB79|uniprotkb:Q7TPF4 intact:EBI-1175174|uniprotkb:O88409|uniprotkb:Q61582|uniprotkb:Q9QWR9|ensembl:ENSMUSP00000052196 psi-mi:prd16_mouse(display_long)|uniprotkb:PR domain zinc finger protein 16(gene name synonym)|uniprotkb:Prdm16(gene name)|psi-mi:Prdm16(display_short)|uniprotkb:Kiaa1675(gene name synonym)|uniprotkb:Mel1(gene name synonym)|uniprotkb:PR domain-containing protein 16(gene name synonym)|uniprotkb:Transcription factor MEL1(gene name synonym) psi-mi:foxc1_mouse(display_long)|uniprotkb:Forkhead-related protein FKHL7(gene name synonym)|uniprotkb:Forkhead-related transcription factor 3(gene name synonym)|uniprotkb:Transcription factor FKH-1(gene name synonym)|uniprotkb:Mesoderm/mesenchyme forkhead 1(gene name synonym)|uniprotkb:Foxc1(gene name)|psi-mi:Foxc1(display_short)|uniprotkb:Fkh1(gene name synonym)|uniprotkb:Fkhl7(gene name synonym)|uniprotkb:Freac3(gene name synonym)|uniprotkb:Mf1(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Hasegawa et al. (2018) imex:IM-28720|pubmed:29320702 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-26604818|imex:IM-28720-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000039410(gene)|ensembl:ENSMUST00000030902(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005829"(cytosol)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0016235"(aggresome)|go:"GO:0017053"(transcription repressor complex)|go:"GO:0019827"(stem cell population maintenance)|go:"GO:0022008"(neurogenesis)|go:"GO:0030512"(negative regulation of transforming growth factor beta receptor signaling pathway)|go:"GO:0030853"(negative regulation of granulocyte differentiation)|go:"GO:0035019"(somatic stem cell population maintenance)|go:"GO:0043457"(regulation of cellular respiration)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0043586"(tongue development)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0046332"(SMAD binding)|go:"GO:0046872"(metal ion binding)|go:"GO:0046974"("histone methyltransferase activity (H3-K9 specific)")|go:"GO:0048468"(cell development)|go:"GO:0050872"(white fat cell differentiation)|go:"GO:0050873"(brown fat cell differentiation)|go:"GO:0060021"(roof of mouth development)|go:"GO:0070828"(heterochromatin organization)|go:"GO:0090336"(positive regulation of brown fat cell differentiation)|go:"GO:0120162"(positive regulation of cold-induced thermogenesis)|go:"GO:0140297"(DNA-binding transcription factor binding)|interpro:IPR001214(SET)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR036236|interpro:IPR044410|mint:A2A935|reactome:R-MMU-3214841|refseq:NP_001277955.1|refseq:NP_001277958.1|refseq:XP_006539236.1|refseq:NP_081780.3|dip:DIP-60593N refseq:NP_032618.2|ensembl:ENSMUSG00000050295(gene)|ensembl:ENSMUST00000062292(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000792"(heterochromatin)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001501"(skeletal system development)|go:"GO:0001503"(ossification)|go:"GO:0001525"(angiogenesis)|go:"GO:0001541"(ovarian follicle development)|go:"GO:0001568"(blood vessel development)|go:"GO:0001654"(eye development)|go:"GO:0001657"(ureteric bud development)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0001756"(somitogenesis)|go:"GO:0001822"(kidney development)|go:"GO:0001945"(lymph vessel development)|go:"GO:0001958"(endochondral ossification)|go:"GO:0001974"(blood vessel remodeling)|go:"GO:0003007"(heart morphogenesis)|go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007219"(Notch signaling pathway)|go:"GO:0007420"(brain development)|go:"GO:0007507"(heart development)|go:"GO:0008134"(transcription factor binding)|go:"GO:0008283"(cell population proliferation)|go:"GO:0008301"(DNA binding, bending)|go:"GO:0008354"(germ cell migration)|go:"GO:0009653"(anatomical structure morphogenesis)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010718"(positive regulation of epithelial to mesenchymal transition)|go:"GO:0014031"(mesenchymal cell development)|go:"GO:0014032"(neural crest cell development)|go:"GO:0016477"(cell migration)|go:"GO:0016525"(negative regulation of angiogenesis)|go:"GO:0021549"(cerebellum development)|go:"GO:0030154"(cell differentiation)|go:"GO:0030199"(collagen fibril organization)|go:"GO:0030203"(glycosaminoglycan metabolic process)|go:"GO:0032808"(lacrimal gland development)|go:"GO:0035050"(embryonic heart tube development)|go:"GO:0036438"(maintenance of lens transparency)|go:"GO:0038084"(vascular endothelial growth factor signaling pathway)|go:"GO:0042475"(odontogenesis of dentin-containing tooth)|go:"GO:0043010"(camera-type eye development)|go:"GO:0043388"(positive regulation of DNA binding)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045618"(positive regulation of keratinocyte differentiation)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045930"(negative regulation of mitotic cell cycle)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046620"(regulation of organ growth)|go:"GO:0048010"(vascular endothelial growth factor receptor signaling pathway)|go:"GO:0048341"(paraxial mesoderm formation)|go:"GO:0048762"(mesenchymal cell differentiation)|go:"GO:0048844"(artery morphogenesis)|go:"GO:0060038"(cardiac muscle cell proliferation)|go:"GO:0070098"(chemokine-mediated signaling pathway)|go:"GO:0071364"(cellular response to epidermal growth factor stimulus)|go:"GO:0072010"(glomerular epithelium development)|go:"GO:0097746"(blood vessel diameter maintenance)|go:"GO:1901491"(negative regulation of lymphangiogenesis)|go:"GO:1901534"(positive regulation of hematopoietic progenitor cell differentiation)|go:"GO:1902038"(positive regulation of hematopoietic stem cell differentiation)|go:"GO:1902257"(negative regulation of apoptotic process involved in outflow tract morphogenesis)|go:"GO:1904798"(positive regulation of core promoter binding)|go:"GO:1990841"(promoter-specific chromatin binding)|go:"GO:1990869"(cellular response to chemokine)|interpro:IPR001766(Fork head transcription factor)|interpro:IPR018122|interpro:IPR030456|interpro:IPR033067|interpro:IPR036388|interpro:IPR036390|mint:Q61572|go:"GO:0055010"(ventricular cardiac muscle tissue morphogenesis) go:"GO:0005634"(nucleus) - - figure legend:F2A ST1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-adipocytes)|taxid:10090(Mus musculus) - 2020/12/10 2021/11/30 rogid:IIoKgZ/wtPhFX+h3JHXbeH2HEpg10090 rogid:hal+IphzDPaYaslJf/KQo5Rgtnc10090 rigid:R7kioghQ/VgGJ/w0NAh+OXuZX6U false flag tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:A2A935 uniprotkb:P43135 intact:EBI-6268248|ensembl:ENSMUSP00000030902|uniprotkb:Q69ZD6|uniprotkb:Q6PB79|uniprotkb:Q7TPF4 intact:EBI-26604650|ensembl:ENSMUSP00000032768 psi-mi:prd16_mouse(display_long)|uniprotkb:PR domain zinc finger protein 16(gene name synonym)|uniprotkb:Prdm16(gene name)|psi-mi:Prdm16(display_short)|uniprotkb:Kiaa1675(gene name synonym)|uniprotkb:Mel1(gene name synonym)|uniprotkb:PR domain-containing protein 16(gene name synonym)|uniprotkb:Transcription factor MEL1(gene name synonym) psi-mi:cot2_mouse(display_long)|uniprotkb:Apolipoprotein AI regulatory protein 1(gene name synonym)|uniprotkb:COUP transcription factor II(gene name synonym)|uniprotkb:Nuclear receptor subfamily 2 group F member 2(gene name synonym)|uniprotkb:Nr2f2(gene name)|psi-mi:Nr2f2(display_short)|uniprotkb:Aporp1(gene name synonym)|uniprotkb:Arp-1(gene name synonym)|uniprotkb:Arp1(gene name synonym)|uniprotkb:Tfcoup2(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Hasegawa et al. (2018) imex:IM-28720|pubmed:29320702 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-26604818|imex:IM-28720-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000039410(gene)|ensembl:ENSMUST00000030902(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005829"(cytosol)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0016235"(aggresome)|go:"GO:0017053"(transcription repressor complex)|go:"GO:0019827"(stem cell population maintenance)|go:"GO:0022008"(neurogenesis)|go:"GO:0030512"(negative regulation of transforming growth factor beta receptor signaling pathway)|go:"GO:0030853"(negative regulation of granulocyte differentiation)|go:"GO:0035019"(somatic stem cell population maintenance)|go:"GO:0043457"(regulation of cellular respiration)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0043586"(tongue development)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0046332"(SMAD binding)|go:"GO:0046872"(metal ion binding)|go:"GO:0046974"("histone methyltransferase activity (H3-K9 specific)")|go:"GO:0048468"(cell development)|go:"GO:0050872"(white fat cell differentiation)|go:"GO:0050873"(brown fat cell differentiation)|go:"GO:0060021"(roof of mouth development)|go:"GO:0070828"(heterochromatin organization)|go:"GO:0090336"(positive regulation of brown fat cell differentiation)|go:"GO:0120162"(positive regulation of cold-induced thermogenesis)|go:"GO:0140297"(DNA-binding transcription factor binding)|interpro:IPR001214(SET)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR036236|interpro:IPR044410|mint:A2A935|reactome:R-MMU-3214841|refseq:NP_001277955.1|refseq:NP_001277958.1|refseq:XP_006539236.1|refseq:NP_081780.3|dip:DIP-60593N ensembl:ENSMUSG00000030551(gene)|ensembl:ENSMUST00000032768(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0001764"(neuron migration)|go:"GO:0001893"(maternal placenta development)|go:"GO:0001937"(negative regulation of endothelial cell proliferation)|go:"GO:0001945"(lymph vessel development)|go:"GO:0001972"(retinoic acid binding)|go:"GO:0003084"(positive regulation of systemic arterial blood pressure)|go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0004879"(nuclear receptor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007519"(skeletal muscle tissue development)|go:"GO:0008270"(zinc ion binding)|go:"GO:0008585"(female gonad development)|go:"GO:0009566"(fertilization)|go:"GO:0009952"(anterior/posterior pattern specification)|go:"GO:0009956"(radial pattern formation)|go:"GO:0010596"(negative regulation of endothelial cell migration)|go:"GO:0030154"(cell differentiation)|go:"GO:0030900"(forebrain development)|go:"GO:0032355"(response to estradiol)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045736"(negative regulation of cyclin-dependent protein serine/threonine kinase activity)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048514"(blood vessel morphogenesis)|go:"GO:0048856"(anatomical structure development)|go:"GO:0060173"(limb development)|go:"GO:0060674"(placenta blood vessel development)|go:"GO:0060707"(trophoblast giant cell differentiation)|go:"GO:0060838"(lymphatic endothelial cell fate commitment)|interpro:IPR000536(Nuclear hormone receptor, ligand-binding, core)|interpro:IPR001628(Zinc finger, nuclear hormone receptor-type)|interpro:IPR001723(Steroid hormone receptor)|interpro:IPR013088(Zinc finger, NHR/GATA-type)|interpro:IPR035500|mint:P43135|refseq:NP_033827.2 go:"GO:0005634"(nucleus) - - figure legend:F2A ST1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-adipocytes)|taxid:10090(Mus musculus) - 2020/12/10 2021/11/30 rogid:IIoKgZ/wtPhFX+h3JHXbeH2HEpg10090 rogid:XsZyqUr06sQQaD3oXAA3IEa6Dug10090 rigid:R7kioghQ/VgGJ/w0NAh+OXuZX6U false flag tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:A2A935 uniprotkb:O08791 intact:EBI-6268248|ensembl:ENSMUSP00000030902|uniprotkb:Q69ZD6|uniprotkb:Q6PB79|uniprotkb:Q7TPF4 intact:EBI-647994|uniprotkb:O08793|ensembl:ENSMUSP00000147829 psi-mi:prd16_mouse(display_long)|uniprotkb:PR domain zinc finger protein 16(gene name synonym)|uniprotkb:Prdm16(gene name)|psi-mi:Prdm16(display_short)|uniprotkb:Kiaa1675(gene name synonym)|uniprotkb:Mel1(gene name synonym)|uniprotkb:PR domain-containing protein 16(gene name synonym)|uniprotkb:Transcription factor MEL1(gene name synonym) psi-mi:coe3_mouse(display_long)|uniprotkb:Early B-cell factor 3(gene name synonym)|uniprotkb:Olf-1/EBF-like 2(gene name synonym)|uniprotkb:Ebf3(gene name)|psi-mi:Ebf3(display_short)|uniprotkb:Coe3(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Hasegawa et al. (2018) imex:IM-28720|pubmed:29320702 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-26604818|imex:IM-28720-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000039410(gene)|ensembl:ENSMUST00000030902(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005829"(cytosol)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0016235"(aggresome)|go:"GO:0017053"(transcription repressor complex)|go:"GO:0019827"(stem cell population maintenance)|go:"GO:0022008"(neurogenesis)|go:"GO:0030512"(negative regulation of transforming growth factor beta receptor signaling pathway)|go:"GO:0030853"(negative regulation of granulocyte differentiation)|go:"GO:0035019"(somatic stem cell population maintenance)|go:"GO:0043457"(regulation of cellular respiration)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0043586"(tongue development)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0046332"(SMAD binding)|go:"GO:0046872"(metal ion binding)|go:"GO:0046974"("histone methyltransferase activity (H3-K9 specific)")|go:"GO:0048468"(cell development)|go:"GO:0050872"(white fat cell differentiation)|go:"GO:0050873"(brown fat cell differentiation)|go:"GO:0060021"(roof of mouth development)|go:"GO:0070828"(heterochromatin organization)|go:"GO:0090336"(positive regulation of brown fat cell differentiation)|go:"GO:0120162"(positive regulation of cold-induced thermogenesis)|go:"GO:0140297"(DNA-binding transcription factor binding)|interpro:IPR001214(SET)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR036236|interpro:IPR044410|mint:A2A935|reactome:R-MMU-3214841|refseq:NP_001277955.1|refseq:NP_001277958.1|refseq:XP_006539236.1|refseq:NP_081780.3|dip:DIP-60593N refseq:NP_001106886.1|refseq:NP_034226.1|interpro:IPR038006|interpro:IPR038173|mint:O08791|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|interpro:IPR002909(Cell surface receptor IPT/TIG)|interpro:IPR003523(Transcription factor COE)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR014756(Immunoglobulin E-set)|interpro:IPR018350|interpro:IPR032200|interpro:IPR032201|ensembl:ENSMUSG00000010476(gene)|ensembl:ENSMUST00000210774(transcript) go:"GO:0005634"(nucleus) - - figure legend:F2A ST1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-adipocytes)|taxid:10090(Mus musculus) - 2020/12/10 2021/11/30 rogid:IIoKgZ/wtPhFX+h3JHXbeH2HEpg10090 rogid:EjmszlImd4hnDec7YLvR1OL3NLo10090 rigid:R7kioghQ/VgGJ/w0NAh+OXuZX6U false flag tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:A2A935 uniprotkb:O08792 intact:EBI-6268248|ensembl:ENSMUSP00000030902|uniprotkb:Q69ZD6|uniprotkb:Q6PB79|uniprotkb:Q7TPF4 intact:EBI-26604609|uniprotkb:Q543D5|ensembl:ENSMUSP00000022637|ensembl:ENSMUSP00000135500|ensembl:ENSMUSP00000135782 psi-mi:prd16_mouse(display_long)|uniprotkb:PR domain zinc finger protein 16(gene name synonym)|uniprotkb:Prdm16(gene name)|psi-mi:Prdm16(display_short)|uniprotkb:Kiaa1675(gene name synonym)|uniprotkb:Mel1(gene name synonym)|uniprotkb:PR domain-containing protein 16(gene name synonym)|uniprotkb:Transcription factor MEL1(gene name synonym) psi-mi:coe2_mouse(display_long)|uniprotkb:Early B-cell factor 2(gene name synonym)|uniprotkb:Metencephalon-mesencephalon-olfactory transcription factor 1(gene name synonym)|uniprotkb:Olf-1/EBF-like 3(gene name synonym)|uniprotkb:Ebf2(gene name)|psi-mi:Ebf2(display_short)|uniprotkb:Coe2(gene name synonym)|uniprotkb:Mmot1(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Hasegawa et al. (2018) imex:IM-28720|pubmed:29320702 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-26604818|imex:IM-28720-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000039410(gene)|ensembl:ENSMUST00000030902(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005829"(cytosol)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0016235"(aggresome)|go:"GO:0017053"(transcription repressor complex)|go:"GO:0019827"(stem cell population maintenance)|go:"GO:0022008"(neurogenesis)|go:"GO:0030512"(negative regulation of transforming growth factor beta receptor signaling pathway)|go:"GO:0030853"(negative regulation of granulocyte differentiation)|go:"GO:0035019"(somatic stem cell population maintenance)|go:"GO:0043457"(regulation of cellular respiration)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0043586"(tongue development)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0046332"(SMAD binding)|go:"GO:0046872"(metal ion binding)|go:"GO:0046974"("histone methyltransferase activity (H3-K9 specific)")|go:"GO:0048468"(cell development)|go:"GO:0050872"(white fat cell differentiation)|go:"GO:0050873"(brown fat cell differentiation)|go:"GO:0060021"(roof of mouth development)|go:"GO:0070828"(heterochromatin organization)|go:"GO:0090336"(positive regulation of brown fat cell differentiation)|go:"GO:0120162"(positive regulation of cold-induced thermogenesis)|go:"GO:0140297"(DNA-binding transcription factor binding)|interpro:IPR001214(SET)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR036236|interpro:IPR044410|mint:A2A935|reactome:R-MMU-3214841|refseq:NP_001277955.1|refseq:NP_001277958.1|refseq:XP_006539236.1|refseq:NP_081780.3|dip:DIP-60593N refseq:NP_001263316.1|refseq:NP_034225.1|refseq:XP_011243247.1|ensembl:ENSMUSG00000022053(gene)|ensembl:ENSMUST00000022637(transcript)|ensembl:ENSMUST00000176029(transcript)|ensembl:ENSMUST00000176161(transcript)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001709"(cell fate determination)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0035563"(positive regulation of chromatin binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|go:"GO:0050873"(brown fat cell differentiation)|go:"GO:0120162"(positive regulation of cold-induced thermogenesis)|interpro:IPR002909(Cell surface receptor IPT/TIG)|interpro:IPR003523(Transcription factor COE)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR014756(Immunoglobulin E-set)|interpro:IPR018350|interpro:IPR032200|interpro:IPR032201|interpro:IPR038006|interpro:IPR038173|mint:O08792|go:"GO:0060612"(adipose tissue development) go:"GO:0005634"(nucleus) - - figure legend:F2A ST1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-adipocytes)|taxid:10090(Mus musculus) - 2020/12/10 2021/11/30 rogid:IIoKgZ/wtPhFX+h3JHXbeH2HEpg10090 rogid:TphQ7NLlgOXT+nDEa56aRr8hkwI10090 rigid:R7kioghQ/VgGJ/w0NAh+OXuZX6U false flag tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:A2A935 uniprotkb:O08785 intact:EBI-6268248|ensembl:ENSMUSP00000030902|uniprotkb:Q69ZD6|uniprotkb:Q6PB79|uniprotkb:Q7TPF4 intact:EBI-79859|ensembl:ENSMUSP00000074656|ensembl:ENSMUSP00000143939 psi-mi:prd16_mouse(display_long)|uniprotkb:PR domain zinc finger protein 16(gene name synonym)|uniprotkb:Prdm16(gene name)|psi-mi:Prdm16(display_short)|uniprotkb:Kiaa1675(gene name synonym)|uniprotkb:Mel1(gene name synonym)|uniprotkb:PR domain-containing protein 16(gene name synonym)|uniprotkb:Transcription factor MEL1(gene name synonym) psi-mi:clock_mouse(display_long)|uniprotkb:Clock(gene name)|psi-mi:Clock(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Hasegawa et al. (2018) imex:IM-28720|pubmed:29320702 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-26604818|imex:IM-28720-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000039410(gene)|ensembl:ENSMUST00000030902(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005829"(cytosol)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0016235"(aggresome)|go:"GO:0017053"(transcription repressor complex)|go:"GO:0019827"(stem cell population maintenance)|go:"GO:0022008"(neurogenesis)|go:"GO:0030512"(negative regulation of transforming growth factor beta receptor signaling pathway)|go:"GO:0030853"(negative regulation of granulocyte differentiation)|go:"GO:0035019"(somatic stem cell population maintenance)|go:"GO:0043457"(regulation of cellular respiration)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0043586"(tongue development)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0046332"(SMAD binding)|go:"GO:0046872"(metal ion binding)|go:"GO:0046974"("histone methyltransferase activity (H3-K9 specific)")|go:"GO:0048468"(cell development)|go:"GO:0050872"(white fat cell differentiation)|go:"GO:0050873"(brown fat cell differentiation)|go:"GO:0060021"(roof of mouth development)|go:"GO:0070828"(heterochromatin organization)|go:"GO:0090336"(positive regulation of brown fat cell differentiation)|go:"GO:0120162"(positive regulation of cold-induced thermogenesis)|go:"GO:0140297"(DNA-binding transcription factor binding)|interpro:IPR001214(SET)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR036236|interpro:IPR044410|mint:A2A935|reactome:R-MMU-3214841|refseq:NP_001277955.1|refseq:NP_001277958.1|refseq:XP_006539236.1|refseq:NP_081780.3|dip:DIP-60593N ensembl:ENSMUSG00000029238(gene)|ensembl:ENSMUST00000075159(transcript)|ensembl:ENSMUST00000202651(transcript)|go:"GO:0000077"(DNA damage checkpoint signaling)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0004402"(histone acetyltransferase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005694"(chromosome)|go:"GO:0005726"(perichromatin fibrils)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005791"(rough endoplasmic reticulum)|go:"GO:0005829"(cytosol)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006473"(protein acetylation)|go:"GO:0007283"(spermatogenesis)|go:"GO:0007623"(circadian rhythm)|go:"GO:0031490"(chromatin DNA binding)|go:"GO:0032922"(circadian regulation of gene expression)|go:"GO:0033391"(chromatoid body)|go:"GO:0042634"(regulation of hair cycle)|go:"GO:0042752"(regulation of circadian rhythm)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0050729"(positive regulation of inflammatory response)|go:"GO:0050796"(regulation of insulin secretion)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|go:"GO:0051775"(response to redox state)|go:"GO:0070888"(E-box binding)|go:"GO:0071479"(cellular response to ionizing radiation)|go:"GO:1990513"(CLOCK-BMAL transcription complex)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046983"(protein dimerization activity)|go:"GO:2000074"(regulation of type B pancreatic cell development)|go:"GO:2000323"(negative regulation of glucocorticoid receptor signaling pathway)|interpro:IPR000014(PAS)|interpro:IPR001067(Nuclear translocator)|interpro:IPR001610(PAC motif)|interpro:IPR011598(Helix-loop-helix DNA-binding)|interpro:IPR013767(PAS fold)|interpro:IPR035965|interpro:IPR036638|mint:O08785|rcsb pdb:4F3L|rcsb pdb:5VJI|rcsb pdb:5VJX|refseq:NP_031741.1|dip:DIP-30958N|refseq:NP_001276755.1|refseq:XP_017176137.1|refseq:XP_017176139.1 go:"GO:0005634"(nucleus) - - figure legend:F2A ST1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-adipocytes)|taxid:10090(Mus musculus) - 2020/12/10 2021/11/30 rogid:IIoKgZ/wtPhFX+h3JHXbeH2HEpg10090 rogid:C2KpIAqSKH1V/v/6hnYPYF/FfPY10090 rigid:R7kioghQ/VgGJ/w0NAh+OXuZX6U false flag tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:A2A935 uniprotkb:Q8K019 intact:EBI-6268248|ensembl:ENSMUSP00000030902|uniprotkb:Q69ZD6|uniprotkb:Q6PB79|uniprotkb:Q7TPF4 intact:EBI-2536273|uniprotkb:Q8C2E9|uniprotkb:Q9CSW5|uniprotkb:Q8BNZ0|ensembl:ENSMUSP00000043583 psi-mi:prd16_mouse(display_long)|uniprotkb:PR domain zinc finger protein 16(gene name synonym)|uniprotkb:Prdm16(gene name)|psi-mi:Prdm16(display_short)|uniprotkb:Kiaa1675(gene name synonym)|uniprotkb:Mel1(gene name synonym)|uniprotkb:PR domain-containing protein 16(gene name synonym)|uniprotkb:Transcription factor MEL1(gene name synonym) psi-mi:bclf1_mouse(display_long)|uniprotkb:Bclaf1(gene name)|psi-mi:Bclaf1(display_short)|uniprotkb:Btf(gene name synonym)|uniprotkb:Kiaa0164(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Hasegawa et al. (2018) imex:IM-28720|pubmed:29320702 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-26604818|imex:IM-28720-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000039410(gene)|ensembl:ENSMUST00000030902(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005829"(cytosol)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0016235"(aggresome)|go:"GO:0017053"(transcription repressor complex)|go:"GO:0019827"(stem cell population maintenance)|go:"GO:0022008"(neurogenesis)|go:"GO:0030512"(negative regulation of transforming growth factor beta receptor signaling pathway)|go:"GO:0030853"(negative regulation of granulocyte differentiation)|go:"GO:0035019"(somatic stem cell population maintenance)|go:"GO:0043457"(regulation of cellular respiration)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0043586"(tongue development)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0046332"(SMAD binding)|go:"GO:0046872"(metal ion binding)|go:"GO:0046974"("histone methyltransferase activity (H3-K9 specific)")|go:"GO:0048468"(cell development)|go:"GO:0050872"(white fat cell differentiation)|go:"GO:0050873"(brown fat cell differentiation)|go:"GO:0060021"(roof of mouth development)|go:"GO:0070828"(heterochromatin organization)|go:"GO:0090336"(positive regulation of brown fat cell differentiation)|go:"GO:0120162"(positive regulation of cold-induced thermogenesis)|go:"GO:0140297"(DNA-binding transcription factor binding)|interpro:IPR001214(SET)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR036236|interpro:IPR044410|mint:A2A935|reactome:R-MMU-3214841|refseq:NP_001277955.1|refseq:NP_001277958.1|refseq:XP_006539236.1|refseq:NP_081780.3|dip:DIP-60593N ensembl:ENSMUSG00000037608(gene)|ensembl:ENSMUST00000043881(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006915"(apoptotic process)|go:"GO:0016592"(mediator complex)|go:"GO:0016607"(nuclear speck)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043620"(regulation of DNA-templated transcription in response to stress)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:1990830"(cellular response to leukemia inhibitory factor)|go:"GO:2000144"(positive regulation of DNA-templated transcription, initiation)|go:"GO:2001022"(positive regulation of response to DNA damage stimulus)|go:"GO:2001244"(positive regulation of intrinsic apoptotic signaling pathway)|interpro:IPR026668|interpro:IPR029199|mint:Q8K019|refseq:NP_001020563.1|refseq:NP_722482.1 go:"GO:0005634"(nucleus) - - figure legend:F2A ST1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-adipocytes)|taxid:10090(Mus musculus) - 2020/12/10 2021/11/30 rogid:IIoKgZ/wtPhFX+h3JHXbeH2HEpg10090 rogid:+9NQPsUgV77P3yH9iK0ZRDIOioM10090 rigid:R7kioghQ/VgGJ/w0NAh+OXuZX6U false flag tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:A2A935 uniprotkb:P28033 intact:EBI-6268248|ensembl:ENSMUSP00000030902|uniprotkb:Q69ZD6|uniprotkb:Q6PB79|uniprotkb:Q7TPF4 intact:EBI-1029979|ensembl:ENSMUSP00000069850 psi-mi:prd16_mouse(display_long)|uniprotkb:PR domain zinc finger protein 16(gene name synonym)|uniprotkb:Prdm16(gene name)|psi-mi:Prdm16(display_short)|uniprotkb:Kiaa1675(gene name synonym)|uniprotkb:Mel1(gene name synonym)|uniprotkb:PR domain-containing protein 16(gene name synonym)|uniprotkb:Transcription factor MEL1(gene name synonym) psi-mi:cebpb_mouse(display_long)|uniprotkb:Cebpb(gene name)|psi-mi:Cebpb(display_short)|uniprotkb:Interleukin-6-dependent-binding protein(gene name synonym)|uniprotkb:Liver-enriched transcriptional activator(gene name synonym)|uniprotkb:AGP/EBP(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Hasegawa et al. (2018) imex:IM-28720|pubmed:29320702 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-26604818|imex:IM-28720-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000039410(gene)|ensembl:ENSMUST00000030902(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005829"(cytosol)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0016235"(aggresome)|go:"GO:0017053"(transcription repressor complex)|go:"GO:0019827"(stem cell population maintenance)|go:"GO:0022008"(neurogenesis)|go:"GO:0030512"(negative regulation of transforming growth factor beta receptor signaling pathway)|go:"GO:0030853"(negative regulation of granulocyte differentiation)|go:"GO:0035019"(somatic stem cell population maintenance)|go:"GO:0043457"(regulation of cellular respiration)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0043586"(tongue development)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0046332"(SMAD binding)|go:"GO:0046872"(metal ion binding)|go:"GO:0046974"("histone methyltransferase activity (H3-K9 specific)")|go:"GO:0048468"(cell development)|go:"GO:0050872"(white fat cell differentiation)|go:"GO:0050873"(brown fat cell differentiation)|go:"GO:0060021"(roof of mouth development)|go:"GO:0070828"(heterochromatin organization)|go:"GO:0090336"(positive regulation of brown fat cell differentiation)|go:"GO:0120162"(positive regulation of cold-induced thermogenesis)|go:"GO:0140297"(DNA-binding transcription factor binding)|interpro:IPR001214(SET)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR036236|interpro:IPR044410|mint:A2A935|reactome:R-MMU-3214841|refseq:NP_001277955.1|refseq:NP_001277958.1|refseq:XP_006539236.1|refseq:NP_081780.3|dip:DIP-60593N refseq:NP_034013.1|ensembl:ENSMUST00000070642(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|ensembl:ENSMUSG00000056501(gene)|go:"GO:0000779"(condensed chromosome, centromeric region)|go:"GO:0000785"(chromatin)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000979"(RNA polymerase II core promoter sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001541"(ovarian follicle development)|go:"GO:0001892"(embryonic placenta development)|go:"GO:0002432"(granuloma formation)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007613"(memory)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0016363"(nuclear matrix)|go:"GO:0019900"(kinase binding)|go:"GO:0030182"(neuron differentiation)|go:"GO:0032496"(response to lipopolysaccharide)|go:"GO:0032675"(regulation of interleukin-6 production)|go:"GO:0032753"(positive regulation of interleukin-4 production)|go:"GO:0033598"(mammary gland epithelial cell proliferation)|go:"GO:0034976"(response to endoplasmic reticulum stress)|go:"GO:0035035"(histone acetyltransferase binding)|go:"GO:0035259"(glucocorticoid receptor binding)|go:"GO:0035711"(T-helper 1 cell activation)|go:"GO:0036488"(CHOP-C/EBP complex)|go:"GO:0042130"(negative regulation of T cell proliferation)|go:"GO:0042742"(defense response to bacterium)|go:"GO:0042802"(identical protein binding)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0044389"(ubiquitin-like protein ligase binding)|go:"GO:0045444"(fat cell differentiation)|go:"GO:0045595"(regulation of cell differentiation)|go:"GO:0045600"(positive regulation of fat cell differentiation)|go:"GO:0045669"(positive regulation of osteoblast differentiation)|go:"GO:0045670"(regulation of osteoclast differentiation)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0050729"(positive regulation of inflammatory response)|go:"GO:0050873"(brown fat cell differentiation)|go:"GO:0060644"(mammary gland epithelial cell differentiation)|go:"GO:0070059"(intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress)|go:"GO:0070169"(positive regulation of biomineral tissue development)|go:"GO:0071222"(cellular response to lipopolysaccharide)|go:"GO:0071230"(cellular response to amino acid stimulus)|go:"GO:0071347"(cellular response to interleukin-1)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0071407"(cellular response to organic cyclic compound)|go:"GO:0072574"(hepatocyte proliferation)|go:"GO:0090575"(RNA polymerase II transcription regulator complex)|go:"GO:0097421"(liver regeneration)|go:"GO:0120162"(positive regulation of cold-induced thermogenesis)|go:"GO:1901329"(regulation of odontoblast differentiation)|go:"GO:1990440"(positive regulation of transcription from RNA polymerase II promoter in response to endoplasmic reticulum stress)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|go:"GO:2000120"(positive regulation of sodium-dependent phosphate transport)|go:"GO:2001198"(regulation of dendritic cell differentiation)|interpro:IPR004827("Basic-leucine zipper (bZIP) transcription factor")|interpro:IPR016468(CCAAT/enhancer-binding)|mint:P28033|rcsb pdb:1CI6|reactome:R-MMU-2559582|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0005737"(cytoplasm)|refseq:NP_001274667.1|refseq:NP_001274668.1|dip:DIP-37539N go:"GO:0005634"(nucleus) - - figure legend:F2A ST1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-adipocytes)|taxid:10090(Mus musculus) - 2020/12/10 2021/11/30 rogid:IIoKgZ/wtPhFX+h3JHXbeH2HEpg10090 rogid:37Pvl6tyxSz6umUVOq0YJflQwEw10090 rigid:R7kioghQ/VgGJ/w0NAh+OXuZX6U false flag tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:A2A935 uniprotkb:P53566 intact:EBI-6268248|ensembl:ENSMUSP00000030902|uniprotkb:Q69ZD6|uniprotkb:Q6PB79|uniprotkb:Q7TPF4 intact:EBI-2644207|uniprotkb:Q91XB6|ensembl:ENSMUSP00000096129 psi-mi:prd16_mouse(display_long)|uniprotkb:PR domain zinc finger protein 16(gene name synonym)|uniprotkb:Prdm16(gene name)|psi-mi:Prdm16(display_short)|uniprotkb:Kiaa1675(gene name synonym)|uniprotkb:Mel1(gene name synonym)|uniprotkb:PR domain-containing protein 16(gene name synonym)|uniprotkb:Transcription factor MEL1(gene name synonym) psi-mi:cebpa_mouse(display_long)|uniprotkb:Cebpa(gene name)|psi-mi:Cebpa(display_short)|uniprotkb:Cebp(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Hasegawa et al. (2018) imex:IM-28720|pubmed:29320702 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-26604818|imex:IM-28720-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000039410(gene)|ensembl:ENSMUST00000030902(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005829"(cytosol)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0016235"(aggresome)|go:"GO:0017053"(transcription repressor complex)|go:"GO:0019827"(stem cell population maintenance)|go:"GO:0022008"(neurogenesis)|go:"GO:0030512"(negative regulation of transforming growth factor beta receptor signaling pathway)|go:"GO:0030853"(negative regulation of granulocyte differentiation)|go:"GO:0035019"(somatic stem cell population maintenance)|go:"GO:0043457"(regulation of cellular respiration)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0043586"(tongue development)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0046332"(SMAD binding)|go:"GO:0046872"(metal ion binding)|go:"GO:0046974"("histone methyltransferase activity (H3-K9 specific)")|go:"GO:0048468"(cell development)|go:"GO:0050872"(white fat cell differentiation)|go:"GO:0050873"(brown fat cell differentiation)|go:"GO:0060021"(roof of mouth development)|go:"GO:0070828"(heterochromatin organization)|go:"GO:0090336"(positive regulation of brown fat cell differentiation)|go:"GO:0120162"(positive regulation of cold-induced thermogenesis)|go:"GO:0140297"(DNA-binding transcription factor binding)|interpro:IPR001214(SET)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR036236|interpro:IPR044410|mint:A2A935|reactome:R-MMU-3214841|refseq:NP_001277955.1|refseq:NP_001277958.1|refseq:XP_006539236.1|refseq:NP_081780.3|dip:DIP-60593N refseq:NP_031704.2|refseq:NP_001274443.1|refseq:NP_001274444.1|refseq:NP_001274450.1|ensembl:ENSMUSG00000034957(gene)|ensembl:ENSMUST00000042985(transcript)|go:"GO:0000050"(urea cycle)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001163"(RNA polymerase I transcription regulatory region sequence-specific DNA binding)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001889"(liver development)|go:"GO:0001892"(embryonic placenta development)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005730"(nucleolus)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006360"(transcription by RNA polymerase I)|go:"GO:0007005"(mitochondrion organization)|go:"GO:0007219"(Notch signaling pathway)|go:"GO:0008134"(transcription factor binding)|go:"GO:0008203"(cholesterol metabolic process)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0016363"(nuclear matrix)|go:"GO:0019221"(cytokine-mediated signaling pathway)|go:"GO:0019900"(kinase binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030099"(myeloid cell differentiation)|go:"GO:0030225"(macrophage differentiation)|go:"GO:0030324"(lung development)|go:"GO:0030851"(granulocyte differentiation)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035189"(Rb-E2F complex)|go:"GO:0036488"(CHOP-C/EBP complex)|go:"GO:0042127"(regulation of cell population proliferation)|go:"GO:0042593"(glucose homeostasis)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0043032"(positive regulation of macrophage activation)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045444"(fat cell differentiation)|go:"GO:0045600"(positive regulation of fat cell differentiation)|go:"GO:0045669"(positive regulation of osteoblast differentiation)|go:"GO:0045786"(negative regulation of cell cycle)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0071356"(cellular response to tumor necrosis factor)|go:"GO:0071407"(cellular response to organic cyclic compound)|go:"GO:0071837"(HMG box domain binding)|go:"GO:0090575"(RNA polymerase II transcription regulator complex)|go:"GO:0097677"(STAT family protein binding)|go:"GO:0140297"(DNA-binding transcription factor binding)|go:"GO:2000144"(positive regulation of DNA-templated transcription, initiation)|interpro:IPR004827("Basic-leucine zipper (bZIP) transcription factor")|interpro:IPR016468(CCAAT/enhancer-binding)|mint:P53566|reactome:R-MMU-9616222|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0045945"(positive regulation of transcription by RNA polymerase III)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0048469"(cell maturation)|go:"GO:0048839"(inner ear development)|go:"GO:0050729"(positive regulation of inflammatory response)|go:"GO:0050872"(white fat cell differentiation)|go:"GO:0050873"(brown fat cell differentiation)|go:"GO:0055088"(lipid homeostasis)|go:"GO:0070102"(interleukin-6-mediated signaling pathway)|go:"GO:0071285"(cellular response to lithium ion)|dip:DIP-44054N go:"GO:0005634"(nucleus) - - figure legend:F2A ST1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-adipocytes)|taxid:10090(Mus musculus) - 2020/12/10 2021/11/30 rogid:IIoKgZ/wtPhFX+h3JHXbeH2HEpg10090 rogid:pGJ6XTpLySPEYPc9uYgeawD6WTk10090 rigid:R7kioghQ/VgGJ/w0NAh+OXuZX6U false flag tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:A2A935 uniprotkb:Q9D2D7 intact:EBI-6268248|ensembl:ENSMUSP00000030902|uniprotkb:Q69ZD6|uniprotkb:Q6PB79|uniprotkb:Q7TPF4 intact:EBI-26604794|ensembl:ENSMUSP00000019482|uniprotkb:Q6PAP3|uniprotkb:Q6ZPQ9 psi-mi:prd16_mouse(display_long)|uniprotkb:PR domain zinc finger protein 16(gene name synonym)|uniprotkb:Prdm16(gene name)|psi-mi:Prdm16(display_short)|uniprotkb:Kiaa1675(gene name synonym)|uniprotkb:Mel1(gene name synonym)|uniprotkb:PR domain-containing protein 16(gene name synonym)|uniprotkb:Transcription factor MEL1(gene name synonym) psi-mi:zn687_mouse(display_long)|uniprotkb:Znf687(gene name)|psi-mi:Znf687(display_short)|uniprotkb:Kiaa1441(gene name synonym)|uniprotkb:Zfp687(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Hasegawa et al. (2018) imex:IM-28720|pubmed:29320702 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-26604818|imex:IM-28720-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000039410(gene)|ensembl:ENSMUST00000030902(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005829"(cytosol)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0016235"(aggresome)|go:"GO:0017053"(transcription repressor complex)|go:"GO:0019827"(stem cell population maintenance)|go:"GO:0022008"(neurogenesis)|go:"GO:0030512"(negative regulation of transforming growth factor beta receptor signaling pathway)|go:"GO:0030853"(negative regulation of granulocyte differentiation)|go:"GO:0035019"(somatic stem cell population maintenance)|go:"GO:0043457"(regulation of cellular respiration)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0043586"(tongue development)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0046332"(SMAD binding)|go:"GO:0046872"(metal ion binding)|go:"GO:0046974"("histone methyltransferase activity (H3-K9 specific)")|go:"GO:0048468"(cell development)|go:"GO:0050872"(white fat cell differentiation)|go:"GO:0050873"(brown fat cell differentiation)|go:"GO:0060021"(roof of mouth development)|go:"GO:0070828"(heterochromatin organization)|go:"GO:0090336"(positive regulation of brown fat cell differentiation)|go:"GO:0120162"(positive regulation of cold-induced thermogenesis)|go:"GO:0140297"(DNA-binding transcription factor binding)|interpro:IPR001214(SET)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR036236|interpro:IPR044410|mint:A2A935|reactome:R-MMU-3214841|refseq:NP_001277955.1|refseq:NP_001277958.1|refseq:XP_006539236.1|refseq:NP_081780.3|dip:DIP-60593N ensembl:ENSMUSG00000019338(gene)|ensembl:ENSMUST00000019482(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0046872"(metal ion binding)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR036236|interpro:IPR041697|mint:Q9D2D7|refseq:NP_084350.1|refseq:XP_006502370.1|refseq:XP_006502371.1 go:"GO:0005634"(nucleus) - - figure legend:F2A ST1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-adipocytes)|taxid:10090(Mus musculus) - 2020/12/10 2021/11/30 rogid:IIoKgZ/wtPhFX+h3JHXbeH2HEpg10090 rogid:AU9kLDLg4V4eH6xPU4TayONQsTE10090 rigid:R7kioghQ/VgGJ/w0NAh+OXuZX6U false flag tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:A2A935 uniprotkb:Q7TSH3 intact:EBI-6268248|ensembl:ENSMUSP00000030902|uniprotkb:Q69ZD6|uniprotkb:Q6PB79|uniprotkb:Q7TPF4 intact:EBI-645074|ensembl:ENSMUSP00000071216|ensembl:ENSMUSP00000126629 psi-mi:prd16_mouse(display_long)|uniprotkb:PR domain zinc finger protein 16(gene name synonym)|uniprotkb:Prdm16(gene name)|psi-mi:Prdm16(display_short)|uniprotkb:Kiaa1675(gene name synonym)|uniprotkb:Mel1(gene name synonym)|uniprotkb:PR domain-containing protein 16(gene name synonym)|uniprotkb:Transcription factor MEL1(gene name synonym) psi-mi:zn516_mouse(display_long)|uniprotkb:Znf516(gene name)|psi-mi:Znf516(display_short)|uniprotkb:Kiaa0222(gene name synonym)|uniprotkb:Zfp516(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Hasegawa et al. (2018) imex:IM-28720|pubmed:29320702 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-26604818|imex:IM-28720-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000039410(gene)|ensembl:ENSMUST00000030902(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005829"(cytosol)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0016235"(aggresome)|go:"GO:0017053"(transcription repressor complex)|go:"GO:0019827"(stem cell population maintenance)|go:"GO:0022008"(neurogenesis)|go:"GO:0030512"(negative regulation of transforming growth factor beta receptor signaling pathway)|go:"GO:0030853"(negative regulation of granulocyte differentiation)|go:"GO:0035019"(somatic stem cell population maintenance)|go:"GO:0043457"(regulation of cellular respiration)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0043586"(tongue development)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0046332"(SMAD binding)|go:"GO:0046872"(metal ion binding)|go:"GO:0046974"("histone methyltransferase activity (H3-K9 specific)")|go:"GO:0048468"(cell development)|go:"GO:0050872"(white fat cell differentiation)|go:"GO:0050873"(brown fat cell differentiation)|go:"GO:0060021"(roof of mouth development)|go:"GO:0070828"(heterochromatin organization)|go:"GO:0090336"(positive regulation of brown fat cell differentiation)|go:"GO:0120162"(positive regulation of cold-induced thermogenesis)|go:"GO:0140297"(DNA-binding transcription factor binding)|interpro:IPR001214(SET)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR036236|interpro:IPR044410|mint:A2A935|reactome:R-MMU-3214841|refseq:NP_001277955.1|refseq:NP_001277958.1|refseq:XP_006539236.1|refseq:NP_081780.3|dip:DIP-60593N refseq:NP_001170935.1|refseq:NP_898854.1|refseq:XP_006526561.1|refseq:XP_006526562.1|refseq:XP_006526563.1|refseq:XP_006526564.1|refseq:XP_006526565.1|refseq:XP_006526566.1|refseq:XP_011245387.1|ensembl:ENSMUSG00000058881(gene)|ensembl:ENSMUST00000071233(transcript)|ensembl:ENSMUST00000171238(transcript)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0000987"(cis-regulatory region sequence-specific DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0009409"(response to cold)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0046872"(metal ion binding)|go:"GO:0050873"(brown fat cell differentiation)|go:"GO:0060612"(adipose tissue development)|go:"GO:0120162"(positive regulation of cold-induced thermogenesis)|go:"GO:0140297"(DNA-binding transcription factor binding)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR036236|mint:Q7TSH3 go:"GO:0005634"(nucleus) - - figure legend:F2A ST1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-adipocytes)|taxid:10090(Mus musculus) - 2020/12/10 2021/11/30 rogid:IIoKgZ/wtPhFX+h3JHXbeH2HEpg10090 rogid:ZHf1LTueAKPZvNSSHt1obLOPQ8010090 rigid:R7kioghQ/VgGJ/w0NAh+OXuZX6U false flag tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:A2A935 uniprotkb:Q99PP2 intact:EBI-6268248|ensembl:ENSMUSP00000030902|uniprotkb:Q69ZD6|uniprotkb:Q6PB79|uniprotkb:Q7TPF4 intact:EBI-16726499|ensembl:ENSMUSP00000109109|uniprotkb:Q3TZL5|uniprotkb:Q8BMX9|uniprotkb:Q9JJ01|uniprotkb:B0V2M3|uniprotkb:B9EK88 psi-mi:prd16_mouse(display_long)|uniprotkb:PR domain zinc finger protein 16(gene name synonym)|uniprotkb:Prdm16(gene name)|psi-mi:Prdm16(display_short)|uniprotkb:Kiaa1675(gene name synonym)|uniprotkb:Mel1(gene name synonym)|uniprotkb:PR domain-containing protein 16(gene name synonym)|uniprotkb:Transcription factor MEL1(gene name synonym) psi-mi:zn318_mouse(display_long)|uniprotkb:Testicular zinc finger protein(gene name synonym)|uniprotkb:Znf318(gene name)|psi-mi:Znf318(display_short)|uniprotkb:Tzf(gene name synonym)|uniprotkb:Zfp318(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Hasegawa et al. (2018) imex:IM-28720|pubmed:29320702 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-26604818|imex:IM-28720-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000039410(gene)|ensembl:ENSMUST00000030902(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005829"(cytosol)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0016235"(aggresome)|go:"GO:0017053"(transcription repressor complex)|go:"GO:0019827"(stem cell population maintenance)|go:"GO:0022008"(neurogenesis)|go:"GO:0030512"(negative regulation of transforming growth factor beta receptor signaling pathway)|go:"GO:0030853"(negative regulation of granulocyte differentiation)|go:"GO:0035019"(somatic stem cell population maintenance)|go:"GO:0043457"(regulation of cellular respiration)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0043586"(tongue development)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0046332"(SMAD binding)|go:"GO:0046872"(metal ion binding)|go:"GO:0046974"("histone methyltransferase activity (H3-K9 specific)")|go:"GO:0048468"(cell development)|go:"GO:0050872"(white fat cell differentiation)|go:"GO:0050873"(brown fat cell differentiation)|go:"GO:0060021"(roof of mouth development)|go:"GO:0070828"(heterochromatin organization)|go:"GO:0090336"(positive regulation of brown fat cell differentiation)|go:"GO:0120162"(positive regulation of cold-induced thermogenesis)|go:"GO:0140297"(DNA-binding transcription factor binding)|interpro:IPR001214(SET)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR036236|interpro:IPR044410|mint:A2A935|reactome:R-MMU-3214841|refseq:NP_001277955.1|refseq:NP_001277958.1|refseq:XP_006539236.1|refseq:NP_081780.3|dip:DIP-60593N ensembl:ENSMUSG00000015597(gene)|ensembl:ENSMUST00000113481(transcript)|go:"GO:0003676"(nucleic acid binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0051321"(meiotic cell cycle)|interpro:IPR003604(Zinc finger, U1-type)|mint:Q99PP2|go:"GO:0005829"(cytosol)|go:"GO:0008270"(zinc ion binding)|go:"GO:0042803"(protein homodimerization activity)|refseq:NP_997554.2|refseq:NP_067321.2 go:"GO:0005634"(nucleus) - - figure legend:F2A ST1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-adipocytes)|taxid:10090(Mus musculus) - 2020/12/10 2021/11/30 rogid:IIoKgZ/wtPhFX+h3JHXbeH2HEpg10090 rogid:YlyBt2UNh34DlqoslOr6yKf8tc410090 rigid:R7kioghQ/VgGJ/w0NAh+OXuZX6U false flag tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:A2A935 uniprotkb:Q9Z2U2 intact:EBI-6268248|ensembl:ENSMUSP00000030902|uniprotkb:Q69ZD6|uniprotkb:Q6PB79|uniprotkb:Q7TPF4 intact:EBI-26604767|ensembl:ENSMUSP00000037233|uniprotkb:B1B0E1|uniprotkb:B1B0E2|uniprotkb:Q8BQX3|uniprotkb:Q8BS87|uniprotkb:Q8CGI6|uniprotkb:Q922D3 psi-mi:prd16_mouse(display_long)|uniprotkb:PR domain zinc finger protein 16(gene name synonym)|uniprotkb:Prdm16(gene name)|psi-mi:Prdm16(display_short)|uniprotkb:Kiaa1675(gene name synonym)|uniprotkb:Mel1(gene name synonym)|uniprotkb:PR domain-containing protein 16(gene name synonym)|uniprotkb:Transcription factor MEL1(gene name synonym) psi-mi:zn292_mouse(display_long)|uniprotkb:Zinc finger protein 15(gene name synonym)|uniprotkb:Zfp292(gene name)|psi-mi:Zfp292(display_short)|uniprotkb:Zfp15(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Hasegawa et al. (2018) imex:IM-28720|pubmed:29320702 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-26604818|imex:IM-28720-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000039410(gene)|ensembl:ENSMUST00000030902(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005829"(cytosol)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0016235"(aggresome)|go:"GO:0017053"(transcription repressor complex)|go:"GO:0019827"(stem cell population maintenance)|go:"GO:0022008"(neurogenesis)|go:"GO:0030512"(negative regulation of transforming growth factor beta receptor signaling pathway)|go:"GO:0030853"(negative regulation of granulocyte differentiation)|go:"GO:0035019"(somatic stem cell population maintenance)|go:"GO:0043457"(regulation of cellular respiration)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0043586"(tongue development)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0046332"(SMAD binding)|go:"GO:0046872"(metal ion binding)|go:"GO:0046974"("histone methyltransferase activity (H3-K9 specific)")|go:"GO:0048468"(cell development)|go:"GO:0050872"(white fat cell differentiation)|go:"GO:0050873"(brown fat cell differentiation)|go:"GO:0060021"(roof of mouth development)|go:"GO:0070828"(heterochromatin organization)|go:"GO:0090336"(positive regulation of brown fat cell differentiation)|go:"GO:0120162"(positive regulation of cold-induced thermogenesis)|go:"GO:0140297"(DNA-binding transcription factor binding)|interpro:IPR001214(SET)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR036236|interpro:IPR044410|mint:A2A935|reactome:R-MMU-3214841|refseq:NP_001277955.1|refseq:NP_001277958.1|refseq:XP_006539236.1|refseq:NP_081780.3|dip:DIP-60593N ensembl:ENSMUSG00000039967(gene)|ensembl:ENSMUST00000047950(transcript)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR036236|mint:Q9Z2U2|refseq:NP_038917.2 go:"GO:0005634"(nucleus) - - figure legend:F2A ST1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-adipocytes)|taxid:10090(Mus musculus) - 2020/12/10 2021/11/30 rogid:IIoKgZ/wtPhFX+h3JHXbeH2HEpg10090 rogid:cJPZeUQy4Cy5O7SErbm4CbdbcLs10090 rigid:R7kioghQ/VgGJ/w0NAh+OXuZX6U false flag tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:A2A935 uniprotkb:O70230 intact:EBI-6268248|ensembl:ENSMUSP00000030902|uniprotkb:Q69ZD6|uniprotkb:Q6PB79|uniprotkb:Q7TPF4 intact:EBI-5691478|uniprotkb:Q8BGB0|uniprotkb:Q8CEI6|uniprotkb:Q8CI27|ensembl:ENSMUSP00000081778 psi-mi:prd16_mouse(display_long)|uniprotkb:PR domain zinc finger protein 16(gene name synonym)|uniprotkb:Prdm16(gene name)|psi-mi:Prdm16(display_short)|uniprotkb:Kiaa1675(gene name synonym)|uniprotkb:Mel1(gene name synonym)|uniprotkb:PR domain-containing protein 16(gene name synonym)|uniprotkb:Transcription factor MEL1(gene name synonym) psi-mi:zn143_mouse(display_long)|uniprotkb:Znf143(gene name)|psi-mi:Znf143(display_short)|uniprotkb:Staf(gene name synonym)|uniprotkb:Zfp143(gene name synonym)|uniprotkb:Selenocysteine tRNA gene transcription-activating factor(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Hasegawa et al. (2018) imex:IM-28720|pubmed:29320702 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-26604818|imex:IM-28720-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000039410(gene)|ensembl:ENSMUST00000030902(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005829"(cytosol)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0016235"(aggresome)|go:"GO:0017053"(transcription repressor complex)|go:"GO:0019827"(stem cell population maintenance)|go:"GO:0022008"(neurogenesis)|go:"GO:0030512"(negative regulation of transforming growth factor beta receptor signaling pathway)|go:"GO:0030853"(negative regulation of granulocyte differentiation)|go:"GO:0035019"(somatic stem cell population maintenance)|go:"GO:0043457"(regulation of cellular respiration)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0043586"(tongue development)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0046332"(SMAD binding)|go:"GO:0046872"(metal ion binding)|go:"GO:0046974"("histone methyltransferase activity (H3-K9 specific)")|go:"GO:0048468"(cell development)|go:"GO:0050872"(white fat cell differentiation)|go:"GO:0050873"(brown fat cell differentiation)|go:"GO:0060021"(roof of mouth development)|go:"GO:0070828"(heterochromatin organization)|go:"GO:0090336"(positive regulation of brown fat cell differentiation)|go:"GO:0120162"(positive regulation of cold-induced thermogenesis)|go:"GO:0140297"(DNA-binding transcription factor binding)|interpro:IPR001214(SET)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR036236|interpro:IPR044410|mint:A2A935|reactome:R-MMU-3214841|refseq:NP_001277955.1|refseq:NP_001277958.1|refseq:XP_006539236.1|refseq:NP_081780.3|dip:DIP-60593N refseq:NP_033307.2|refseq:XP_006507595.1|ensembl:ENSMUSG00000061079(gene)|ensembl:ENSMUST00000084727(transcript)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0031519"(PcG protein complex)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|go:"GO:0048661"(positive regulation of smooth muscle cell proliferation)|go:"GO:1905382"(positive regulation of snRNA transcription by RNA polymerase II)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR036236|mint:O70230 go:"GO:0005634"(nucleus) - - figure legend:F2A ST1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-adipocytes)|taxid:10090(Mus musculus) - 2020/12/10 2021/11/30 rogid:IIoKgZ/wtPhFX+h3JHXbeH2HEpg10090 rogid:+e1PvPJVtgCiOQ+9iG+Z1oANwcg10090 rigid:R7kioghQ/VgGJ/w0NAh+OXuZX6U false flag tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:A2A935 uniprotkb:Q8C0C0 intact:EBI-6268248|ensembl:ENSMUSP00000030902|uniprotkb:Q69ZD6|uniprotkb:Q6PB79|uniprotkb:Q7TPF4 intact:EBI-646042|ensembl:ENSMUSP00000094164 psi-mi:prd16_mouse(display_long)|uniprotkb:PR domain zinc finger protein 16(gene name synonym)|uniprotkb:Prdm16(gene name)|psi-mi:Prdm16(display_short)|uniprotkb:Kiaa1675(gene name synonym)|uniprotkb:Mel1(gene name synonym)|uniprotkb:PR domain-containing protein 16(gene name synonym)|uniprotkb:Transcription factor MEL1(gene name synonym) psi-mi:zhx2_mouse(display_long)|uniprotkb:Zinc finger and homeodomain protein 2(gene name synonym)|uniprotkb:Alpha-fetoprotein regulator 1(gene name synonym)|uniprotkb:Regulator of AFP(gene name synonym)|uniprotkb:Zhx2(gene name)|psi-mi:Zhx2(display_short)|uniprotkb:Afr1(gene name synonym)|uniprotkb:Raf(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Hasegawa et al. (2018) imex:IM-28720|pubmed:29320702 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-26604818|imex:IM-28720-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000039410(gene)|ensembl:ENSMUST00000030902(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005829"(cytosol)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0016235"(aggresome)|go:"GO:0017053"(transcription repressor complex)|go:"GO:0019827"(stem cell population maintenance)|go:"GO:0022008"(neurogenesis)|go:"GO:0030512"(negative regulation of transforming growth factor beta receptor signaling pathway)|go:"GO:0030853"(negative regulation of granulocyte differentiation)|go:"GO:0035019"(somatic stem cell population maintenance)|go:"GO:0043457"(regulation of cellular respiration)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0043586"(tongue development)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0046332"(SMAD binding)|go:"GO:0046872"(metal ion binding)|go:"GO:0046974"("histone methyltransferase activity (H3-K9 specific)")|go:"GO:0048468"(cell development)|go:"GO:0050872"(white fat cell differentiation)|go:"GO:0050873"(brown fat cell differentiation)|go:"GO:0060021"(roof of mouth development)|go:"GO:0070828"(heterochromatin organization)|go:"GO:0090336"(positive regulation of brown fat cell differentiation)|go:"GO:0120162"(positive regulation of cold-induced thermogenesis)|go:"GO:0140297"(DNA-binding transcription factor binding)|interpro:IPR001214(SET)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR036236|interpro:IPR044410|mint:A2A935|reactome:R-MMU-3214841|refseq:NP_001277955.1|refseq:NP_001277958.1|refseq:XP_006539236.1|refseq:NP_081780.3|dip:DIP-60593N refseq:NP_955520.1|refseq:XP_011243990.1|refseq:XP_011243991.1|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006402"(mRNA catabolic process)|go:"GO:0035019"(somatic stem cell population maintenance)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0045665"(negative regulation of neuron differentiation)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0046872"(metal ion binding)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0060040"(retinal bipolar neuron differentiation)|interpro:IPR001356(Homeobox)|interpro:IPR009057(Homeodomain-like)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR036236|interpro:IPR041057|mint:Q8C0C0|ensembl:ENSMUSG00000071757(gene)|ensembl:ENSMUST00000096430(transcript) go:"GO:0005634"(nucleus) - - figure legend:F2A ST1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-adipocytes)|taxid:10090(Mus musculus) - 2020/12/10 2021/11/30 rogid:IIoKgZ/wtPhFX+h3JHXbeH2HEpg10090 rogid:CfLzg3RnMJLrG5O8s42wXRyNhLk10090 rigid:R7kioghQ/VgGJ/w0NAh+OXuZX6U false flag tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification)