#ID(s) interactor A ID(s) interactor B Alt. ID(s) interactor A Alt. ID(s) interactor B Alias(es) interactor A Alias(es) interactor B Interaction detection method(s) Publication 1st author(s) Publication Identifier(s) Taxid interactor A Taxid interactor B Interaction type(s) Source database(s) Interaction identifier(s) Confidence value(s) Expansion method(s) Biological role(s) interactor A Biological role(s) interactor B Experimental role(s) interactor A Experimental role(s) interactor B Type(s) interactor A Type(s) interactor B Xref(s) interactor A Xref(s) interactor B Interaction Xref(s) Annotation(s) interactor A Annotation(s) interactor B Interaction annotation(s) Host organism(s) Interaction parameter(s) Creation date Update date Checksum(s) interactor A Checksum(s) interactor B Interaction Checksum(s) Negative Feature(s) interactor A Feature(s) interactor B Stoichiometry(s) interactor A Stoichiometry(s) interactor B Identification method participant A Identification method participant B uniprotkb:O76003 uniprotkb:Q96JA1 intact:EBI-374781|uniprotkb:Q96CE0|uniprotkb:Q9P1B0|uniprotkb:Q9P1B1|uniprotkb:B3KMP7|uniprotkb:B3KMQ5|uniprotkb:Q5JV01|ensembl:ENSP00000330836|ensembl:ENSP00000357633|ensembl:ENSP00000435445|uniprotkb:D3DRG2 intact:EBI-2865191|uniprotkb:Q9BYB8|uniprotkb:Q96CF9|uniprotkb:Q6IQ51|uniprotkb:Q9UFI4|ensembl:ENSP00000273261 psi-mi:glrx3_human(display_long)|uniprotkb:GLRX3(gene name)|psi-mi:GLRX3(display_short)|uniprotkb:Thioredoxin-like protein 2(gene name synonym)|uniprotkb:PKC-interacting cousin of thioredoxin(gene name synonym)|uniprotkb:PKC-theta-interacting protein(gene name synonym)|uniprotkb:PICOT(gene name synonym)|uniprotkb:HUSSY-22(orf name)|uniprotkb:TXNL2(gene name synonym) psi-mi:lrig1_human(display_long)|uniprotkb:LRIG1(gene name)|psi-mi:LRIG1(display_short)|uniprotkb:LIG1(gene name synonym) psi-mi:"MI:0018"(two hybrid) Faraz et al. (2018) imex:IM-27729|pubmed:29317492 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-25431502|imex:IM-27729-1 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000108010(gene)|ensembl:ENST00000331244(transcript)|ensembl:ENST00000368644(transcript)|ensembl:ENST00000481034(transcript)|go:"GO:0002026"(regulation of the force of heart contraction)|go:"GO:0003723"(RNA binding)|go:"GO:0005080"(protein kinase C binding)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0005938"(cell cortex)|go:"GO:0006879"(cellular iron ion homeostasis)|go:"GO:0010614"(negative regulation of cardiac muscle hypertrophy)|go:"GO:0030018"(Z disc)|go:"GO:0030425"(dendrite)|go:"GO:0042802"(identical protein binding)|go:"GO:0044571"([2Fe-2S] cluster assembly)|go:"GO:0046872"(metal ion binding)|go:"GO:0051536"(iron-sulfur cluster binding)|go:"GO:0097428"(protein maturation by iron-sulfur cluster transfer)|go:"GO:0097573"(glutathione oxidoreductase activity)|interpro:IPR002109(Glutaredoxin)|interpro:IPR004480(Glutaredoxin-related protein)|interpro:IPR013766(Thioredoxin domain)|interpro:IPR033658|interpro:IPR036249|mint:O76003|rcsb pdb:2DIY|rcsb pdb:2WZ9|rcsb pdb:2YAN|rcsb pdb:3ZYW|reactome:R-HSA-917937|refseq:NP_001186797.1|refseq:NP_006532.2|dip:DIP-31306N refseq:NP_056356.2|ensembl:ENSG00000144749(gene)|ensembl:ENST00000273261(transcript)|go:"GO:0005615"(extracellular space)|go:"GO:0005886"(plasma membrane)|go:"GO:0007605"(sensory perception of sound)|go:"GO:0016021"(integral component of membrane)|go:"GO:0022405"(hair cycle process)|go:"GO:0031012"(extracellular matrix)|go:"GO:0032474"(otolith morphogenesis)|go:"GO:0060384"(innervation)|interpro:IPR000372(Leucine-rich repeat, cysteine-rich flanking region, N-terminal)|interpro:IPR000483(Cysteine-rich flanking region, C-terminal)|interpro:IPR001611(Leucine-rich repeat)|interpro:IPR003591(Leucine-rich repeat, typical subtype)|interpro:IPR003598(Immunoglobulin subtype 2)|interpro:IPR003599(Immunoglobulin subtype)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR013098(Immunoglobulin I-set)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR032675|interpro:IPR036179|rcsb pdb:4U7L|rcsb pdb:4U7M|reactome:R-HSA-177929|reactome:R-HSA-6807004 - - - figure legend:Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2020/01/29 2020/02/19 rogid:iKUSt6zbNzzXSKvW+vXMq3hKsEM9606 rogid:bnp2t5D9UqLg2EqOUJg6P6BVaE09606 rigid:x0MQXQJnPm+npOq5570Wdcy5qrE false sufficient binding region:322-335 sufficient binding region:816-1093 - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q05516 uniprotkb:Q96JA1 intact:EBI-711925|ensembl:ENSP00000338157|ensembl:ENSP00000376721|ensembl:ENSP00000506794|ensembl:ENSP00000506894|ensembl:ENSP00000506924|ensembl:ENSP00000506953|ensembl:ENSP00000507788|ensembl:ENSP00000508351|uniprotkb:Q8TAL4 intact:EBI-2865191|uniprotkb:Q9BYB8|uniprotkb:Q96CF9|uniprotkb:Q6IQ51|uniprotkb:Q9UFI4|ensembl:ENSP00000273261 psi-mi:zbt16_human(display_long)|uniprotkb:Zinc finger protein PLZF(gene name synonym)|uniprotkb:Promyelocytic leukemia zinc finger protein(gene name synonym)|uniprotkb:Zinc finger protein 145(gene name synonym)|uniprotkb:ZBTB16(gene name)|psi-mi:ZBTB16(display_short)|uniprotkb:PLZF(gene name synonym)|uniprotkb:ZNF145(gene name synonym) psi-mi:lrig1_human(display_long)|uniprotkb:LRIG1(gene name)|psi-mi:LRIG1(display_short)|uniprotkb:LIG1(gene name synonym) psi-mi:"MI:0018"(two hybrid) Faraz et al. (2018) imex:IM-27729|pubmed:29317492 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-25431506|imex:IM-27729-3 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000109906(gene)|ensembl:ENST00000335953(transcript)|ensembl:ENST00000392996(transcript)|ensembl:ENST00000682278(transcript)|ensembl:ENST00000682697(transcript)|ensembl:ENST00000682971(transcript)|ensembl:ENST00000683318(transcript)|ensembl:ENST00000683554(transcript)|ensembl:ENST00000684295(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0001222"(transcription corepressor binding)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001823"(mesonephros development)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006915"(apoptotic process)|go:"GO:0007417"(central nervous system development)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0009880"(embryonic pattern specification)|go:"GO:0009952"(anterior/posterior pattern specification)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0016604"(nuclear body)|go:"GO:0016605"(PML body)|go:"GO:0016607"(nuclear speck)|go:"GO:0017053"(transcription repressor complex)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030097"(hemopoiesis)|go:"GO:0030099"(myeloid cell differentiation)|go:"GO:0032332"(positive regulation of chondrocyte differentiation)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034504"(protein localization to nucleus)|go:"GO:0035116"(embryonic hindlimb morphogenesis)|go:"GO:0035136"(forelimb morphogenesis)|go:"GO:0042733"(embryonic digit morphogenesis)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043931"(ossification involved in bone maturation)|go:"GO:0045600"(positive regulation of fat cell differentiation)|go:"GO:0045638"(negative regulation of myeloid cell differentiation)|go:"GO:0045778"(positive regulation of ossification)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0046872"(metal ion binding)|go:"GO:0048133"(male germ-line stem cell asymmetric division)|go:"GO:0051138"(positive regulation of NK T cell differentiation)|go:"GO:0051216"(cartilage development)|go:"GO:0061036"(positive regulation of cartilage development)|interpro:IPR000210(BTB/POZ-like)|interpro:IPR011333(BTB/POZ fold)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR036236|mint:Q05516|rcsb pdb:1BUO|rcsb pdb:1CS3|reactome:R-HSA-8951664|reactome:R-HSA-983168|refseq:NP_001018011.1|refseq:NP_005997.2|refseq:XP_016873746.1|refseq:XP_016873747.1|refseq:XP_016873748.1|dip:DIP-2654N refseq:NP_056356.2|ensembl:ENSG00000144749(gene)|ensembl:ENST00000273261(transcript)|go:"GO:0005615"(extracellular space)|go:"GO:0005886"(plasma membrane)|go:"GO:0007605"(sensory perception of sound)|go:"GO:0016021"(integral component of membrane)|go:"GO:0022405"(hair cycle process)|go:"GO:0031012"(extracellular matrix)|go:"GO:0032474"(otolith morphogenesis)|go:"GO:0060384"(innervation)|interpro:IPR000372(Leucine-rich repeat, cysteine-rich flanking region, N-terminal)|interpro:IPR000483(Cysteine-rich flanking region, C-terminal)|interpro:IPR001611(Leucine-rich repeat)|interpro:IPR003591(Leucine-rich repeat, typical subtype)|interpro:IPR003598(Immunoglobulin subtype 2)|interpro:IPR003599(Immunoglobulin subtype)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR013098(Immunoglobulin I-set)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR032675|interpro:IPR036179|rcsb pdb:4U7L|rcsb pdb:4U7M|reactome:R-HSA-177929|reactome:R-HSA-6807004 - - - figure legend:Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2020/01/29 2020/02/19 rogid:wJmkU9GC3S18VXyYd8asd+hN+yU9606 rogid:bnp2t5D9UqLg2EqOUJg6P6BVaE09606 rigid:GQkfnEJaqol47GXWL8BMFGwynww false sufficient binding region:374-673 sufficient binding region:816-1093 - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification)