#ID(s) interactor A	ID(s) interactor B	Alt. ID(s) interactor A	Alt. ID(s) interactor B	Alias(es) interactor A	Alias(es) interactor B	Interaction detection method(s)	Publication 1st author(s)	Publication Identifier(s)	Taxid interactor A	Taxid interactor B	Interaction type(s)	Source database(s)	Interaction identifier(s)	Confidence value(s)	Expansion method(s)	Biological role(s) interactor A	Biological role(s) interactor B	Experimental role(s) interactor A	Experimental role(s) interactor B	Type(s) interactor A	Type(s) interactor B	Xref(s) interactor A	Xref(s) interactor B	Interaction Xref(s)	Annotation(s) interactor A	Annotation(s) interactor B	Interaction annotation(s)	Host organism(s)	Interaction parameter(s)	Creation date	Update date	Checksum(s) interactor A	Checksum(s) interactor B	Interaction Checksum(s)	Negative	Feature(s) interactor A	Feature(s) interactor B	Stoichiometry(s) interactor A	Stoichiometry(s) interactor B	Identification method participant A	Identification method participant B
uniprotkb:P9WIT1	uniprotkb:Q8CDJ3	intact:EBI-25767539|uniprotkb:L0TBU2|uniprotkb:Q50685|uniprotkb:Q7D7C5	intact:EBI-3506699|uniprotkb:Q69ZY1|uniprotkb:Q6PFY6|uniprotkb:Q8C6N0|uniprotkb:Q8R3M3|ensembl:ENSMUSP00000039047|ensembl:ENSMUSP00000153718	psi-mi:y2280_myctu(display_long)|uniprotkb:Rv2280(locus name)	psi-mi:bakor_mouse(display_long)|uniprotkb:Atg14(gene name)|psi-mi:Atg14(display_short)|uniprotkb:D14Ertd436e(gene name synonym)|uniprotkb:Kiaa0831(gene name synonym)|uniprotkb:Autophagy-related protein 14-like protein(gene name synonym)|uniprotkb:Atg14L(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2018)	doi:10.1093/nar/gkx1173|imex:IM-28235|pubmed:29165646	taxid:83332(myctu)|taxid:83332("Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)")	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0471"(MINT)	intact:EBI-25767557|imex:IM-28235-221	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	go:"GO:0005618"(cell wall)|go:"GO:0005886"(plasma membrane)|go:"GO:0016491"(oxidoreductase activity)|go:"GO:0071949"(FAD binding)|interpro:IPR016169(CO dehydrogenase flavoprotein-like, FAD-binding, subdomain 2)|mint:P9WIT1|refseq:WP_003411690.1|interpro:IPR016166(FAD-binding, type 2)|interpro:IPR036318|interpro:IPR016164(FAD-linked oxidase-like, C-terminal)|interpro:IPR004113(FAD-linked oxidase, C-terminal)|interpro:IPR006094(FAD linked oxidase, N-terminal)|interpro:IPR016171(Vanillyl-alcohol oxidase, C-terminal subdomain 2)	refseq:NP_766187.1|ensembl:ENSMUSG00000037526(gene)|ensembl:ENSMUST00000042988(transcript)|ensembl:ENSMUST00000226299(transcript)|go:"GO:0000045"(autophagosome assembly)|go:"GO:0000421"(autophagosome membrane)|go:"GO:0000423"(mitophagy)|go:"GO:0001932"(regulation of protein phosphorylation)|go:"GO:0001933"(negative regulation of protein phosphorylation)|go:"GO:0001934"(positive regulation of protein phosphorylation)|go:"GO:0005776"(autophagosome)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005930"(axoneme)|go:"GO:0006914"(autophagy)|go:"GO:0008333"(endosome to lysosome transport)|go:"GO:0009267"(cellular response to starvation)|go:"GO:0010608"(posttranscriptional regulation of gene expression)|go:"GO:0016236"(macroautophagy)|go:"GO:0016240"(autophagosome membrane docking)|go:"GO:0034045"(phagophore assembly site membrane)|go:"GO:0035032"(phosphatidylinositol 3-kinase complex, class III)|go:"GO:0042149"(cellular response to glucose starvation)|go:"GO:0043552"(positive regulation of phosphatidylinositol 3-kinase activity)|go:"GO:0044233"(mitochondria-associated endoplasmic reticulum membrane)|go:"GO:0045335"(phagocytic vesicle)|go:"GO:0051020"(GTPase binding)|go:"GO:0090207"(regulation of triglyceride metabolic process)|go:"GO:0097629"(extrinsic component of omegasome membrane)|go:"GO:0097632"(extrinsic component of phagophore assembly site membrane)|go:"GO:0098780"(response to mitochondrial depolarisation)|interpro:IPR018791|mint:Q8CDJ3|reactome:R-MMU-1632852|dip:DIP-60849N	-	-	-	figure legend:ST5|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2020/07/08	2020/08/14	rogid:TvFI3uuw9zREl1q0DeWIsHmCSEk83332	rogid:Ha+zYY4aNPLZH0LQPz9s1SSK9R410090	rigid:KOw4+37CbI3mkVekY8LsgGFP0fM	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P71619	uniprotkb:Q6P4T0	intact:EBI-25767582|uniprotkb:F2GLA0|uniprotkb:I6YAD4	intact:EBI-11065106|uniprotkb:Q6PHN0|uniprotkb:Q6ZQC4|uniprotkb:Q3U9I1|uniprotkb:Q8R213|ensembl:ENSMUSP00000046412	psi-mi:p71619_myctu(display_long)|uniprotkb:ugpB(gene name)|psi-mi:ugpB(display_short)|uniprotkb:Rv2833c(locus name)	psi-mi:atg2a_mouse(display_long)|uniprotkb:Atg2a(gene name)|psi-mi:Atg2a(display_short)|uniprotkb:Kiaa0404(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2018)	doi:10.1093/nar/gkx1173|imex:IM-28235|pubmed:29165646	taxid:83332(myctu)|taxid:83332("Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)")	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0471"(MINT)	intact:EBI-25767595|imex:IM-28235-223	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	go:"GO:0005886"(plasma membrane)|rcsb pdb:6R1B|mint:P71619|refseq:NP_217349.1|refseq:WP_003414501.1|interpro:IPR006059(Bacterial extracellular solute-binding, family 1)|interpro:IPR006311(Twin-arginine translocation pathway signal)	refseq:NP_919329.2|ensembl:ENSMUSG00000024773(gene)|ensembl:ENSMUST00000045351(transcript)|go:"GO:0000045"(autophagosome assembly)|go:"GO:0000407"(phagophore assembly site)|go:"GO:0000422"(autophagy of mitochondrion)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005811"(lipid droplet)|go:"GO:0019898"(extrinsic component of membrane)|go:"GO:0032266"(phosphatidylinositol-3-phosphate binding)|go:"GO:0034045"(phagophore assembly site membrane)|go:"GO:0034727"(piecemeal microautophagy of the nucleus)|go:"GO:0044805"(late nucleophagy)|go:"GO:0061709"(reticulophagy)|interpro:IPR015412(ATG2, C-terminal)|interpro:IPR026849|interpro:IPR026854|mint:Q6P4T0	-	-	-	figure legend:ST5|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2020/07/08	2020/08/14	rogid:ldo4FA/3ddzSo1mfnNEPte27F1083332	rogid:OORsj2CMXtjK9qGZ9EqzVQgyYsk10090	rigid:W76Uk+AMGa6GSopRv8t7y4SJVJk	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P9WN37	uniprotkb:Q6P4T0	intact:EBI-25767601|uniprotkb:L0T968|uniprotkb:P64245|uniprotkb:Q10378	intact:EBI-11065106|uniprotkb:Q6PHN0|uniprotkb:Q6ZQC4|uniprotkb:Q3U9I1|uniprotkb:Q8R213|ensembl:ENSMUSP00000046412	psi-mi:gln1a_myctu(display_long)|uniprotkb:glnA2(gene name)|psi-mi:glnA2(display_short)|uniprotkb:Glutamate--ammonia ligase(gene name synonym)|uniprotkb:Glutamine synthetase I alpha(gene name synonym)|uniprotkb:MTCY190.33c(orf name)|uniprotkb:MTCY427.03c(orf name)|uniprotkb:Rv2222c(locus name)	psi-mi:atg2a_mouse(display_long)|uniprotkb:Atg2a(gene name)|psi-mi:Atg2a(display_short)|uniprotkb:Kiaa0404(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2018)	doi:10.1093/nar/gkx1173|imex:IM-28235|pubmed:29165646	taxid:83332(myctu)|taxid:83332("Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)")	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0471"(MINT)	intact:EBI-25767627|imex:IM-28235-3	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	go:"GO:0004356"(glutamate-ammonia ligase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0006542"(glutamine biosynthetic process)|go:"GO:0046872"(metal ion binding)|go:"GO:0050001"(D-glutaminase activity)|mint:P9WN37|refseq:NP_216738.1|refseq:WP_003411482.1|interpro:IPR008147(Glutamine synthetase, beta-Grasp)|interpro:IPR036651|interpro:IPR014746(Glutamine synthetase/guanido kinase, catalytic region)|interpro:IPR008146(Glutamine synthetase, catalytic region)|interpro:IPR027303	refseq:NP_919329.2|ensembl:ENSMUSG00000024773(gene)|ensembl:ENSMUST00000045351(transcript)|go:"GO:0000045"(autophagosome assembly)|go:"GO:0000407"(phagophore assembly site)|go:"GO:0000422"(autophagy of mitochondrion)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005811"(lipid droplet)|go:"GO:0019898"(extrinsic component of membrane)|go:"GO:0032266"(phosphatidylinositol-3-phosphate binding)|go:"GO:0034045"(phagophore assembly site membrane)|go:"GO:0034727"(piecemeal microautophagy of the nucleus)|go:"GO:0044805"(late nucleophagy)|go:"GO:0061709"(reticulophagy)|interpro:IPR015412(ATG2, C-terminal)|interpro:IPR026849|interpro:IPR026854|mint:Q6P4T0	-	-	-	figure legend:ST5|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2020/07/08	2020/08/14	rogid:LDIpolmw5yhv2iG5+8HKbWlwT8883332	rogid:OORsj2CMXtjK9qGZ9EqzVQgyYsk10090	rigid:OxdTTVdzXQMKoJthuQAq3HB4pFw	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:O07177	uniprotkb:Q6P4T0	intact:EBI-25767633|uniprotkb:L0T5L4	intact:EBI-11065106|uniprotkb:Q6PHN0|uniprotkb:Q6ZQC4|uniprotkb:Q3U9I1|uniprotkb:Q8R213|ensembl:ENSMUSP00000046412	psi-mi:mak1_myctu(display_long)|uniprotkb:mak(gene name)|psi-mi:mak(display_short)|uniprotkb:Maltose-1-phosphate synthase(gene name synonym)|uniprotkb:Rv0127(locus name)	psi-mi:atg2a_mouse(display_long)|uniprotkb:Atg2a(gene name)|psi-mi:Atg2a(display_short)|uniprotkb:Kiaa0404(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2018)	doi:10.1093/nar/gkx1173|imex:IM-28235|pubmed:29165646	taxid:83332(myctu)|taxid:83332("Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)")	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0471"(MINT)	intact:EBI-25767652|imex:IM-28235-5	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	go:"GO:0005978"(glycogen biosynthetic process)|go:"GO:0005992"(trehalose biosynthetic process)|go:"GO:0016301"(kinase activity)|go:"GO:0046835"(carbohydrate phosphorylation)|rcsb pdb:4O7O|rcsb pdb:4O7P|go:"GO:0005524"(ATP binding)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|mint:O07177|refseq:NP_214641.1|refseq:WP_003916610.1|interpro:IPR011009(Protein kinase-like)|interpro:IPR040999	refseq:NP_919329.2|ensembl:ENSMUSG00000024773(gene)|ensembl:ENSMUST00000045351(transcript)|go:"GO:0000045"(autophagosome assembly)|go:"GO:0000407"(phagophore assembly site)|go:"GO:0000422"(autophagy of mitochondrion)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005811"(lipid droplet)|go:"GO:0019898"(extrinsic component of membrane)|go:"GO:0032266"(phosphatidylinositol-3-phosphate binding)|go:"GO:0034045"(phagophore assembly site membrane)|go:"GO:0034727"(piecemeal microautophagy of the nucleus)|go:"GO:0044805"(late nucleophagy)|go:"GO:0061709"(reticulophagy)|interpro:IPR015412(ATG2, C-terminal)|interpro:IPR026849|interpro:IPR026854|mint:Q6P4T0	-	-	-	figure legend:ST5|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2020/07/08	2020/08/14	rogid:kpl6jZ4UbJUq/kfAlHBYpJAJV4E83332	rogid:OORsj2CMXtjK9qGZ9EqzVQgyYsk10090	rigid:CI2eJNk279MmWN/FV/7d4M+KXkw	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P9WIT1	uniprotkb:Q6P4T0	intact:EBI-25767539|uniprotkb:L0TBU2|uniprotkb:Q50685|uniprotkb:Q7D7C5	intact:EBI-11065106|uniprotkb:Q6PHN0|uniprotkb:Q6ZQC4|uniprotkb:Q3U9I1|uniprotkb:Q8R213|ensembl:ENSMUSP00000046412	psi-mi:y2280_myctu(display_long)|uniprotkb:Rv2280(locus name)	psi-mi:atg2a_mouse(display_long)|uniprotkb:Atg2a(gene name)|psi-mi:Atg2a(display_short)|uniprotkb:Kiaa0404(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2018)	doi:10.1093/nar/gkx1173|imex:IM-28235|pubmed:29165646	taxid:83332(myctu)|taxid:83332("Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)")	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0471"(MINT)	intact:EBI-25767658|imex:IM-28235-81	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	go:"GO:0005618"(cell wall)|go:"GO:0005886"(plasma membrane)|go:"GO:0016491"(oxidoreductase activity)|go:"GO:0071949"(FAD binding)|interpro:IPR016169(CO dehydrogenase flavoprotein-like, FAD-binding, subdomain 2)|mint:P9WIT1|refseq:WP_003411690.1|interpro:IPR016166(FAD-binding, type 2)|interpro:IPR036318|interpro:IPR016164(FAD-linked oxidase-like, C-terminal)|interpro:IPR004113(FAD-linked oxidase, C-terminal)|interpro:IPR006094(FAD linked oxidase, N-terminal)|interpro:IPR016171(Vanillyl-alcohol oxidase, C-terminal subdomain 2)	refseq:NP_919329.2|ensembl:ENSMUSG00000024773(gene)|ensembl:ENSMUST00000045351(transcript)|go:"GO:0000045"(autophagosome assembly)|go:"GO:0000407"(phagophore assembly site)|go:"GO:0000422"(autophagy of mitochondrion)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005811"(lipid droplet)|go:"GO:0019898"(extrinsic component of membrane)|go:"GO:0032266"(phosphatidylinositol-3-phosphate binding)|go:"GO:0034045"(phagophore assembly site membrane)|go:"GO:0034727"(piecemeal microautophagy of the nucleus)|go:"GO:0044805"(late nucleophagy)|go:"GO:0061709"(reticulophagy)|interpro:IPR015412(ATG2, C-terminal)|interpro:IPR026849|interpro:IPR026854|mint:Q6P4T0	-	-	-	figure legend:ST5|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2020/07/08	2020/08/14	rogid:TvFI3uuw9zREl1q0DeWIsHmCSEk83332	rogid:OORsj2CMXtjK9qGZ9EqzVQgyYsk10090	rigid:+NuleQ9TldQAK1nT5kq0Ef2X6NM	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q6P4T0	uniprotkb:P9WNI7	intact:EBI-11065106|uniprotkb:Q6PHN0|uniprotkb:Q6ZQC4|uniprotkb:Q3U9I1|uniprotkb:Q8R213|ensembl:ENSMUSP00000046412	intact:EBI-9027314|uniprotkb:P95242|uniprotkb:L0T9C9	psi-mi:atg2a_mouse(display_long)|uniprotkb:Atg2a(gene name)|psi-mi:Atg2a(display_short)|uniprotkb:Kiaa0404(gene name synonym)	psi-mi:esxo_myctu(display_long)|uniprotkb:esxO(gene name)|psi-mi:esxO(display_short)|uniprotkb:MTCY98.15c(orf name)|uniprotkb:Rv2346c(locus name)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2018)	doi:10.1093/nar/gkx1173|imex:IM-28235|pubmed:29165646	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:83332(myctu)|taxid:83332("Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)")	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0471"(MINT)	intact:EBI-25767664|imex:IM-28235-41	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_919329.2|ensembl:ENSMUSG00000024773(gene)|ensembl:ENSMUST00000045351(transcript)|go:"GO:0000045"(autophagosome assembly)|go:"GO:0000407"(phagophore assembly site)|go:"GO:0000422"(autophagy of mitochondrion)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005811"(lipid droplet)|go:"GO:0019898"(extrinsic component of membrane)|go:"GO:0032266"(phosphatidylinositol-3-phosphate binding)|go:"GO:0034045"(phagophore assembly site membrane)|go:"GO:0034727"(piecemeal microautophagy of the nucleus)|go:"GO:0044805"(late nucleophagy)|go:"GO:0061709"(reticulophagy)|interpro:IPR015412(ATG2, C-terminal)|interpro:IPR026849|interpro:IPR026854|mint:Q6P4T0	mint:P9WNI7|interpro:IPR036689|interpro:IPR009416(Protein of unknown function DUF1066)|interpro:IPR010310(Protein of unknown function DUF909)|refseq:NP_216862.1|refseq:WP_003899283.1|go:"GO:0005576"(extracellular region)|go:"GO:0005618"(cell wall)|go:"GO:0005886"(plasma membrane)|rcsb pdb:3OGI|rcsb pdb:4GZR	-	-	-	figure legend:ST5|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2020/07/08	2020/08/14	rogid:OORsj2CMXtjK9qGZ9EqzVQgyYsk10090	rogid:jYoNmHY+G6+S39CX1qRFCxjy0xw83332	rigid:i1sS5BTKMBjLrcXMoe/NnfPmR7U	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P9WJB9	uniprotkb:Q6P4T0	intact:EBI-25767670|uniprotkb:L0TE21|uniprotkb:O69744|uniprotkb:Q7D4P0	intact:EBI-11065106|uniprotkb:Q6PHN0|uniprotkb:Q6ZQC4|uniprotkb:Q3U9I1|uniprotkb:Q8R213|ensembl:ENSMUSP00000046412	psi-mi:espl_myctu(display_long)|uniprotkb:espL(gene name)|psi-mi:espL(display_short)|uniprotkb:Rv3880c(locus name)	psi-mi:atg2a_mouse(display_long)|uniprotkb:Atg2a(gene name)|psi-mi:Atg2a(display_short)|uniprotkb:Kiaa0404(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2018)	doi:10.1093/nar/gkx1173|imex:IM-28235|pubmed:29165646	taxid:83332(myctu)|taxid:83332("Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)")	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0471"(MINT)	intact:EBI-25767685|imex:IM-28235-181	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	go:"GO:0003677"(DNA binding)|go:"GO:0005618"(cell wall)|go:"GO:0005886"(plasma membrane)|go:"GO:0052170"(suppression by symbiont of host innate immune response)|mint:P9WJB9|refseq:NP_218397.1|refseq:WP_003399988.1|interpro:IPR036894|interpro:IPR004401(Conserved hypothetical protein CHP00103)	refseq:NP_919329.2|ensembl:ENSMUSG00000024773(gene)|ensembl:ENSMUST00000045351(transcript)|go:"GO:0000045"(autophagosome assembly)|go:"GO:0000407"(phagophore assembly site)|go:"GO:0000422"(autophagy of mitochondrion)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005811"(lipid droplet)|go:"GO:0019898"(extrinsic component of membrane)|go:"GO:0032266"(phosphatidylinositol-3-phosphate binding)|go:"GO:0034045"(phagophore assembly site membrane)|go:"GO:0034727"(piecemeal microautophagy of the nucleus)|go:"GO:0044805"(late nucleophagy)|go:"GO:0061709"(reticulophagy)|interpro:IPR015412(ATG2, C-terminal)|interpro:IPR026849|interpro:IPR026854|mint:Q6P4T0	-	-	-	figure legend:ST5|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2020/07/08	2020/08/14	rogid:BspTx2RZuhJaQ319NBDIyOreqfE83332	rogid:OORsj2CMXtjK9qGZ9EqzVQgyYsk10090	rigid:Z1GnLWnD63/OWYUxfPBjXr5ijDw	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P9WP17	uniprotkb:Q6P4T0	intact:EBI-25767691|uniprotkb:L0T3B0|uniprotkb:O07247	intact:EBI-11065106|uniprotkb:Q6PHN0|uniprotkb:Q6ZQC4|uniprotkb:Q3U9I1|uniprotkb:Q8R213|ensembl:ENSMUSP00000046412	psi-mi:dcdb_myctu(display_long)|uniprotkb:dcd(gene name)|psi-mi:dcd(display_short)|uniprotkb:"Bifunctional dCTP deaminase:dUTPase"(gene name synonym)|uniprotkb:DCD-DUT(gene name synonym)|uniprotkb:MTCY63.26(orf name)|uniprotkb:Rv0321(locus name)	psi-mi:atg2a_mouse(display_long)|uniprotkb:Atg2a(gene name)|psi-mi:Atg2a(display_short)|uniprotkb:Kiaa0404(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2018)	doi:10.1093/nar/gkx1173|imex:IM-28235|pubmed:29165646	taxid:83332(myctu)|taxid:83332("Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)")	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0471"(MINT)	intact:EBI-25767715|imex:IM-28235-83	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	go:"GO:0000166"(nucleotide binding)|go:"GO:0004170"(dUTP diphosphatase activity)|go:"GO:0006226"(dUMP biosynthetic process)|go:"GO:0006229"(dUTP biosynthetic process)|go:"GO:0008829"(dCTP deaminase activity)|go:"GO:0015949"(nucleobase-containing small molecule interconversion)|go:"GO:0033973"("dCTP deaminase (dUMP-forming) activity")|rcsb pdb:2QLP|rcsb pdb:2QXX|rcsb pdb:4A6A|mint:P9WP17|refseq:NP_214835.1|refseq:WP_003898399.1|interpro:IPR011962(Deoxycytidine triphosphate deaminase)|interpro:IPR029054|interpro:IPR036157|interpro:IPR033704	refseq:NP_919329.2|ensembl:ENSMUSG00000024773(gene)|ensembl:ENSMUST00000045351(transcript)|go:"GO:0000045"(autophagosome assembly)|go:"GO:0000407"(phagophore assembly site)|go:"GO:0000422"(autophagy of mitochondrion)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005811"(lipid droplet)|go:"GO:0019898"(extrinsic component of membrane)|go:"GO:0032266"(phosphatidylinositol-3-phosphate binding)|go:"GO:0034045"(phagophore assembly site membrane)|go:"GO:0034727"(piecemeal microautophagy of the nucleus)|go:"GO:0044805"(late nucleophagy)|go:"GO:0061709"(reticulophagy)|interpro:IPR015412(ATG2, C-terminal)|interpro:IPR026849|interpro:IPR026854|mint:Q6P4T0	-	-	-	figure legend:ST5|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2020/07/08	2020/08/14	rogid:7Llq0DbdMabIKeH06jyXlfJfD3083332	rogid:OORsj2CMXtjK9qGZ9EqzVQgyYsk10090	rigid:jnXP1z2o3QGSv8NNUte8imJjHk8	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:O07422	uniprotkb:Q6P4T0	intact:EBI-25767563|uniprotkb:F2GLX6|uniprotkb:I6Y302|uniprotkb:Q7DAB9	intact:EBI-11065106|uniprotkb:Q6PHN0|uniprotkb:Q6ZQC4|uniprotkb:Q3U9I1|uniprotkb:Q8R213|ensembl:ENSMUSP00000046412	psi-mi:o07422_myctu(display_long)|uniprotkb:Rv0178(locus name)	psi-mi:atg2a_mouse(display_long)|uniprotkb:Atg2a(gene name)|psi-mi:Atg2a(display_short)|uniprotkb:Kiaa0404(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2018)	doi:10.1093/nar/gkx1173|imex:IM-28235|pubmed:29165646	taxid:83332(myctu)|taxid:83332("Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)")	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0471"(MINT)	intact:EBI-25767721|imex:IM-28235-101	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	go:"GO:0005576"(extracellular region)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0051701"(biological process involved in interaction with host)|mint:O07422|refseq:NP_214692.1|refseq:WP_003899844.1	refseq:NP_919329.2|ensembl:ENSMUSG00000024773(gene)|ensembl:ENSMUST00000045351(transcript)|go:"GO:0000045"(autophagosome assembly)|go:"GO:0000407"(phagophore assembly site)|go:"GO:0000422"(autophagy of mitochondrion)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005811"(lipid droplet)|go:"GO:0019898"(extrinsic component of membrane)|go:"GO:0032266"(phosphatidylinositol-3-phosphate binding)|go:"GO:0034045"(phagophore assembly site membrane)|go:"GO:0034727"(piecemeal microautophagy of the nucleus)|go:"GO:0044805"(late nucleophagy)|go:"GO:0061709"(reticulophagy)|interpro:IPR015412(ATG2, C-terminal)|interpro:IPR026849|interpro:IPR026854|mint:Q6P4T0	-	-	-	figure legend:ST5|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2020/07/08	2020/08/14	rogid:lGOg72Osvz8819m674JzGUcHEj483332	rogid:OORsj2CMXtjK9qGZ9EqzVQgyYsk10090	rigid:5pKsXAo7msRkS/h29p4onEbbyn8	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:I6Y946	uniprotkb:Q6P4T0	intact:EBI-25767727	intact:EBI-11065106|uniprotkb:Q6PHN0|uniprotkb:Q6ZQC4|uniprotkb:Q3U9I1|uniprotkb:Q8R213|ensembl:ENSMUSP00000046412	psi-mi:i6y946_myctu(display_long)|uniprotkb:Rv0925c(locus name)	psi-mi:atg2a_mouse(display_long)|uniprotkb:Atg2a(gene name)|psi-mi:Atg2a(display_short)|uniprotkb:Kiaa0404(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2018)	doi:10.1093/nar/gkx1173|imex:IM-28235|pubmed:29165646	taxid:83332(myctu)|taxid:83332("Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)")	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0471"(MINT)	intact:EBI-25767736|imex:IM-28235-103	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	go:"GO:0016491"(oxidoreductase activity)|mint:I6Y946|refseq:NP_215440.1|refseq:WP_003404764.1|interpro:IPR029039|interpro:IPR005025(NADPH-dependent FMN reductase)	refseq:NP_919329.2|ensembl:ENSMUSG00000024773(gene)|ensembl:ENSMUST00000045351(transcript)|go:"GO:0000045"(autophagosome assembly)|go:"GO:0000407"(phagophore assembly site)|go:"GO:0000422"(autophagy of mitochondrion)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005811"(lipid droplet)|go:"GO:0019898"(extrinsic component of membrane)|go:"GO:0032266"(phosphatidylinositol-3-phosphate binding)|go:"GO:0034045"(phagophore assembly site membrane)|go:"GO:0034727"(piecemeal microautophagy of the nucleus)|go:"GO:0044805"(late nucleophagy)|go:"GO:0061709"(reticulophagy)|interpro:IPR015412(ATG2, C-terminal)|interpro:IPR026849|interpro:IPR026854|mint:Q6P4T0	-	-	-	figure legend:ST5|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2020/07/08	2020/08/14	rogid:JOW06LtizimdrjJdMmMnM9ru8n083332	rogid:OORsj2CMXtjK9qGZ9EqzVQgyYsk10090	rigid:122NPgZeqt67kfRMXtImTEcGkZ8	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:O50440	uniprotkb:Q6P4T0	intact:EBI-25767742|uniprotkb:I6XXB2|uniprotkb:L0T7J5	intact:EBI-11065106|uniprotkb:Q6PHN0|uniprotkb:Q6ZQC4|uniprotkb:Q3U9I1|uniprotkb:Q8R213|ensembl:ENSMUSP00000046412	psi-mi:chp2_myctu(display_long)|uniprotkb:chp2(gene name)|psi-mi:chp2(display_short)|uniprotkb:LH57_06500(orf name)|uniprotkb:P425_01234(orf name)|uniprotkb:Rv1184c(locus name)|uniprotkb:RVBD_1184c(locus name)	psi-mi:atg2a_mouse(display_long)|uniprotkb:Atg2a(gene name)|psi-mi:Atg2a(display_short)|uniprotkb:Kiaa0404(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2018)	doi:10.1093/nar/gkx1173|imex:IM-28235|pubmed:29165646	taxid:83332(myctu)|taxid:83332("Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)")	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0471"(MINT)	intact:EBI-25767760|imex:IM-28235-261	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	go:"GO:0005886"(plasma membrane)|go:"GO:0006629"(lipid metabolic process)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016746"(acyltransferase activity)|go:"GO:0005618"(cell wall)|mint:O50440|refseq:NP_215700.1|refseq:WP_003406195.1|interpro:IPR013228(PE-PPE, C-terminal)	refseq:NP_919329.2|ensembl:ENSMUSG00000024773(gene)|ensembl:ENSMUST00000045351(transcript)|go:"GO:0000045"(autophagosome assembly)|go:"GO:0000407"(phagophore assembly site)|go:"GO:0000422"(autophagy of mitochondrion)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005811"(lipid droplet)|go:"GO:0019898"(extrinsic component of membrane)|go:"GO:0032266"(phosphatidylinositol-3-phosphate binding)|go:"GO:0034045"(phagophore assembly site membrane)|go:"GO:0034727"(piecemeal microautophagy of the nucleus)|go:"GO:0044805"(late nucleophagy)|go:"GO:0061709"(reticulophagy)|interpro:IPR015412(ATG2, C-terminal)|interpro:IPR026849|interpro:IPR026854|mint:Q6P4T0	-	-	-	figure legend:ST5|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2020/07/08	2020/08/14	rogid:IXzYfb7UxFgqBXPZ6NZHLy3hdTc83332	rogid:OORsj2CMXtjK9qGZ9EqzVQgyYsk10090	rigid:0HD7PdRbicbg9paLtz2L8iL2TaI	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:O53319	uniprotkb:Q6P4T0	intact:EBI-25767766|uniprotkb:I6X6K2|uniprotkb:L0TEH7	intact:EBI-11065106|uniprotkb:Q6PHN0|uniprotkb:Q6ZQC4|uniprotkb:Q3U9I1|uniprotkb:Q8R213|ensembl:ENSMUSP00000046412	psi-mi:o53319_myctu(display_long)|uniprotkb:Rv3169(locus name)	psi-mi:atg2a_mouse(display_long)|uniprotkb:Atg2a(gene name)|psi-mi:Atg2a(display_short)|uniprotkb:Kiaa0404(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2018)	doi:10.1093/nar/gkx1173|imex:IM-28235|pubmed:29165646	taxid:83332(myctu)|taxid:83332("Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)")	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0471"(MINT)	intact:EBI-25767775|imex:IM-28235-43	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	go:"GO:0005886"(plasma membrane)|mint:O53319|refseq:NP_217685.1|refseq:WP_003416605.1	refseq:NP_919329.2|ensembl:ENSMUSG00000024773(gene)|ensembl:ENSMUST00000045351(transcript)|go:"GO:0000045"(autophagosome assembly)|go:"GO:0000407"(phagophore assembly site)|go:"GO:0000422"(autophagy of mitochondrion)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005811"(lipid droplet)|go:"GO:0019898"(extrinsic component of membrane)|go:"GO:0032266"(phosphatidylinositol-3-phosphate binding)|go:"GO:0034045"(phagophore assembly site membrane)|go:"GO:0034727"(piecemeal microautophagy of the nucleus)|go:"GO:0044805"(late nucleophagy)|go:"GO:0061709"(reticulophagy)|interpro:IPR015412(ATG2, C-terminal)|interpro:IPR026849|interpro:IPR026854|mint:Q6P4T0	-	-	-	figure legend:ST5|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2020/07/08	2020/08/14	rogid:Gd1O5B5qTAQflXzn9MR+6fgqvDs83332	rogid:OORsj2CMXtjK9qGZ9EqzVQgyYsk10090	rigid:3rdQVUrRlozFoZ/7h3JQlHn9HyU	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:O69689	uniprotkb:Q6P4T0	intact:EBI-25767781|uniprotkb:F2GFU4|uniprotkb:I6Y4D4|uniprotkb:Q7D501	intact:EBI-11065106|uniprotkb:Q6PHN0|uniprotkb:Q6ZQC4|uniprotkb:Q3U9I1|uniprotkb:Q8R213|ensembl:ENSMUSP00000046412	psi-mi:aspat_myctu(display_long)|uniprotkb:Rv3722c(locus name)	psi-mi:atg2a_mouse(display_long)|uniprotkb:Atg2a(gene name)|psi-mi:Atg2a(display_short)|uniprotkb:Kiaa0404(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2018)	doi:10.1093/nar/gkx1173|imex:IM-28235|pubmed:29165646	taxid:83332(myctu)|taxid:83332("Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)")	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0471"(MINT)	intact:EBI-25767797|imex:IM-28235-281	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	go:"GO:0004069"("L-aspartate:2-oxoglutarate aminotransferase activity")|go:"GO:0005576"(extracellular region)|rcsb pdb:5C6U|rcsb pdb:6U78|rcsb pdb:6U7A|mint:O69689|refseq:NP_218239.2|refseq:WP_003899653.1|interpro:IPR024551|interpro:IPR015424(Pyridoxal phosphate-dependent transferase, major region)|interpro:IPR015422(Pyridoxal phosphate-dependent transferase, major region, subdomain 2)|interpro:IPR015421(Pyridoxal phosphate-dependent transferase, major region, subdomain 1)	refseq:NP_919329.2|ensembl:ENSMUSG00000024773(gene)|ensembl:ENSMUST00000045351(transcript)|go:"GO:0000045"(autophagosome assembly)|go:"GO:0000407"(phagophore assembly site)|go:"GO:0000422"(autophagy of mitochondrion)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005811"(lipid droplet)|go:"GO:0019898"(extrinsic component of membrane)|go:"GO:0032266"(phosphatidylinositol-3-phosphate binding)|go:"GO:0034045"(phagophore assembly site membrane)|go:"GO:0034727"(piecemeal microautophagy of the nucleus)|go:"GO:0044805"(late nucleophagy)|go:"GO:0061709"(reticulophagy)|interpro:IPR015412(ATG2, C-terminal)|interpro:IPR026849|interpro:IPR026854|mint:Q6P4T0	-	-	-	figure legend:ST5|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2020/07/08	2020/08/14	rogid:TGWnUCrIwLrRrMnna5+/w33GpgA83332	rogid:OORsj2CMXtjK9qGZ9EqzVQgyYsk10090	rigid:uoa08HLz+BPfhlF3T4ZtCjKOXYk	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:O69689	uniprotkb:Q6P4T0	intact:EBI-25767781|uniprotkb:F2GFU4|uniprotkb:I6Y4D4|uniprotkb:Q7D501	intact:EBI-11065106|uniprotkb:Q6PHN0|uniprotkb:Q6ZQC4|uniprotkb:Q3U9I1|uniprotkb:Q8R213|ensembl:ENSMUSP00000046412	psi-mi:aspat_myctu(display_long)|uniprotkb:Rv3722c(locus name)	psi-mi:atg2a_mouse(display_long)|uniprotkb:Atg2a(gene name)|psi-mi:Atg2a(display_short)|uniprotkb:Kiaa0404(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2018)	doi:10.1093/nar/gkx1173|imex:IM-28235|pubmed:29165646	taxid:83332(myctu)|taxid:83332("Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)")	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0471"(MINT)	intact:EBI-25767803|imex:IM-28235-301	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	go:"GO:0004069"("L-aspartate:2-oxoglutarate aminotransferase activity")|go:"GO:0005576"(extracellular region)|rcsb pdb:5C6U|rcsb pdb:6U78|rcsb pdb:6U7A|mint:O69689|refseq:NP_218239.2|refseq:WP_003899653.1|interpro:IPR024551|interpro:IPR015424(Pyridoxal phosphate-dependent transferase, major region)|interpro:IPR015422(Pyridoxal phosphate-dependent transferase, major region, subdomain 2)|interpro:IPR015421(Pyridoxal phosphate-dependent transferase, major region, subdomain 1)	refseq:NP_919329.2|ensembl:ENSMUSG00000024773(gene)|ensembl:ENSMUST00000045351(transcript)|go:"GO:0000045"(autophagosome assembly)|go:"GO:0000407"(phagophore assembly site)|go:"GO:0000422"(autophagy of mitochondrion)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005811"(lipid droplet)|go:"GO:0019898"(extrinsic component of membrane)|go:"GO:0032266"(phosphatidylinositol-3-phosphate binding)|go:"GO:0034045"(phagophore assembly site membrane)|go:"GO:0034727"(piecemeal microautophagy of the nucleus)|go:"GO:0044805"(late nucleophagy)|go:"GO:0061709"(reticulophagy)|interpro:IPR015412(ATG2, C-terminal)|interpro:IPR026849|interpro:IPR026854|mint:Q6P4T0	-	-	-	figure legend:ST5|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2020/07/08	2020/08/14	rogid:TGWnUCrIwLrRrMnna5+/w33GpgA83332	rogid:OORsj2CMXtjK9qGZ9EqzVQgyYsk10090	rigid:uoa08HLz+BPfhlF3T4ZtCjKOXYk	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P71619	uniprotkb:Q6P4T0	intact:EBI-25767582|uniprotkb:F2GLA0|uniprotkb:I6YAD4	intact:EBI-11065106|uniprotkb:Q6PHN0|uniprotkb:Q6ZQC4|uniprotkb:Q3U9I1|uniprotkb:Q8R213|ensembl:ENSMUSP00000046412	psi-mi:p71619_myctu(display_long)|uniprotkb:ugpB(gene name)|psi-mi:ugpB(display_short)|uniprotkb:Rv2833c(locus name)	psi-mi:atg2a_mouse(display_long)|uniprotkb:Atg2a(gene name)|psi-mi:Atg2a(display_short)|uniprotkb:Kiaa0404(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2018)	doi:10.1093/nar/gkx1173|imex:IM-28235|pubmed:29165646	taxid:83332(myctu)|taxid:83332("Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)")	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0471"(MINT)	intact:EBI-25767809|imex:IM-28235-7	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	go:"GO:0005886"(plasma membrane)|rcsb pdb:6R1B|mint:P71619|refseq:NP_217349.1|refseq:WP_003414501.1|interpro:IPR006059(Bacterial extracellular solute-binding, family 1)|interpro:IPR006311(Twin-arginine translocation pathway signal)	refseq:NP_919329.2|ensembl:ENSMUSG00000024773(gene)|ensembl:ENSMUST00000045351(transcript)|go:"GO:0000045"(autophagosome assembly)|go:"GO:0000407"(phagophore assembly site)|go:"GO:0000422"(autophagy of mitochondrion)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005811"(lipid droplet)|go:"GO:0019898"(extrinsic component of membrane)|go:"GO:0032266"(phosphatidylinositol-3-phosphate binding)|go:"GO:0034045"(phagophore assembly site membrane)|go:"GO:0034727"(piecemeal microautophagy of the nucleus)|go:"GO:0044805"(late nucleophagy)|go:"GO:0061709"(reticulophagy)|interpro:IPR015412(ATG2, C-terminal)|interpro:IPR026849|interpro:IPR026854|mint:Q6P4T0	-	-	-	figure legend:ST5|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2020/07/08	2020/08/14	rogid:ldo4FA/3ddzSo1mfnNEPte27F1083332	rogid:OORsj2CMXtjK9qGZ9EqzVQgyYsk10090	rigid:W76Uk+AMGa6GSopRv8t7y4SJVJk	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P9WN37	uniprotkb:Q6P4T0	intact:EBI-25767601|uniprotkb:L0T968|uniprotkb:P64245|uniprotkb:Q10378	intact:EBI-11065106|uniprotkb:Q6PHN0|uniprotkb:Q6ZQC4|uniprotkb:Q3U9I1|uniprotkb:Q8R213|ensembl:ENSMUSP00000046412	psi-mi:gln1a_myctu(display_long)|uniprotkb:glnA2(gene name)|psi-mi:glnA2(display_short)|uniprotkb:Glutamate--ammonia ligase(gene name synonym)|uniprotkb:Glutamine synthetase I alpha(gene name synonym)|uniprotkb:MTCY190.33c(orf name)|uniprotkb:MTCY427.03c(orf name)|uniprotkb:Rv2222c(locus name)	psi-mi:atg2a_mouse(display_long)|uniprotkb:Atg2a(gene name)|psi-mi:Atg2a(display_short)|uniprotkb:Kiaa0404(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2018)	doi:10.1093/nar/gkx1173|imex:IM-28235|pubmed:29165646	taxid:83332(myctu)|taxid:83332("Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)")	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0471"(MINT)	intact:EBI-25767815|imex:IM-28235-303	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	go:"GO:0004356"(glutamate-ammonia ligase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0006542"(glutamine biosynthetic process)|go:"GO:0046872"(metal ion binding)|go:"GO:0050001"(D-glutaminase activity)|mint:P9WN37|refseq:NP_216738.1|refseq:WP_003411482.1|interpro:IPR008147(Glutamine synthetase, beta-Grasp)|interpro:IPR036651|interpro:IPR014746(Glutamine synthetase/guanido kinase, catalytic region)|interpro:IPR008146(Glutamine synthetase, catalytic region)|interpro:IPR027303	refseq:NP_919329.2|ensembl:ENSMUSG00000024773(gene)|ensembl:ENSMUST00000045351(transcript)|go:"GO:0000045"(autophagosome assembly)|go:"GO:0000407"(phagophore assembly site)|go:"GO:0000422"(autophagy of mitochondrion)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005811"(lipid droplet)|go:"GO:0019898"(extrinsic component of membrane)|go:"GO:0032266"(phosphatidylinositol-3-phosphate binding)|go:"GO:0034045"(phagophore assembly site membrane)|go:"GO:0034727"(piecemeal microautophagy of the nucleus)|go:"GO:0044805"(late nucleophagy)|go:"GO:0061709"(reticulophagy)|interpro:IPR015412(ATG2, C-terminal)|interpro:IPR026849|interpro:IPR026854|mint:Q6P4T0	-	-	-	figure legend:ST5|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2020/07/08	2020/08/14	rogid:LDIpolmw5yhv2iG5+8HKbWlwT8883332	rogid:OORsj2CMXtjK9qGZ9EqzVQgyYsk10090	rigid:OxdTTVdzXQMKoJthuQAq3HB4pFw	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P9WIT1	uniprotkb:Q6P4T0	intact:EBI-25767539|uniprotkb:L0TBU2|uniprotkb:Q50685|uniprotkb:Q7D7C5	intact:EBI-11065106|uniprotkb:Q6PHN0|uniprotkb:Q6ZQC4|uniprotkb:Q3U9I1|uniprotkb:Q8R213|ensembl:ENSMUSP00000046412	psi-mi:y2280_myctu(display_long)|uniprotkb:Rv2280(locus name)	psi-mi:atg2a_mouse(display_long)|uniprotkb:Atg2a(gene name)|psi-mi:Atg2a(display_short)|uniprotkb:Kiaa0404(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2018)	doi:10.1093/nar/gkx1173|imex:IM-28235|pubmed:29165646	taxid:83332(myctu)|taxid:83332("Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)")	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0471"(MINT)	intact:EBI-25767821|imex:IM-28235-263	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	go:"GO:0005618"(cell wall)|go:"GO:0005886"(plasma membrane)|go:"GO:0016491"(oxidoreductase activity)|go:"GO:0071949"(FAD binding)|interpro:IPR016169(CO dehydrogenase flavoprotein-like, FAD-binding, subdomain 2)|mint:P9WIT1|refseq:WP_003411690.1|interpro:IPR016166(FAD-binding, type 2)|interpro:IPR036318|interpro:IPR016164(FAD-linked oxidase-like, C-terminal)|interpro:IPR004113(FAD-linked oxidase, C-terminal)|interpro:IPR006094(FAD linked oxidase, N-terminal)|interpro:IPR016171(Vanillyl-alcohol oxidase, C-terminal subdomain 2)	refseq:NP_919329.2|ensembl:ENSMUSG00000024773(gene)|ensembl:ENSMUST00000045351(transcript)|go:"GO:0000045"(autophagosome assembly)|go:"GO:0000407"(phagophore assembly site)|go:"GO:0000422"(autophagy of mitochondrion)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005811"(lipid droplet)|go:"GO:0019898"(extrinsic component of membrane)|go:"GO:0032266"(phosphatidylinositol-3-phosphate binding)|go:"GO:0034045"(phagophore assembly site membrane)|go:"GO:0034727"(piecemeal microautophagy of the nucleus)|go:"GO:0044805"(late nucleophagy)|go:"GO:0061709"(reticulophagy)|interpro:IPR015412(ATG2, C-terminal)|interpro:IPR026849|interpro:IPR026854|mint:Q6P4T0	-	-	-	figure legend:ST5|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2020/07/08	2020/08/14	rogid:TvFI3uuw9zREl1q0DeWIsHmCSEk83332	rogid:OORsj2CMXtjK9qGZ9EqzVQgyYsk10090	rigid:+NuleQ9TldQAK1nT5kq0Ef2X6NM	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P9WJB9	uniprotkb:Q6P4T0	intact:EBI-25767670|uniprotkb:L0TE21|uniprotkb:O69744|uniprotkb:Q7D4P0	intact:EBI-11065106|uniprotkb:Q6PHN0|uniprotkb:Q6ZQC4|uniprotkb:Q3U9I1|uniprotkb:Q8R213|ensembl:ENSMUSP00000046412	psi-mi:espl_myctu(display_long)|uniprotkb:espL(gene name)|psi-mi:espL(display_short)|uniprotkb:Rv3880c(locus name)	psi-mi:atg2a_mouse(display_long)|uniprotkb:Atg2a(gene name)|psi-mi:Atg2a(display_short)|uniprotkb:Kiaa0404(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2018)	doi:10.1093/nar/gkx1173|imex:IM-28235|pubmed:29165646	taxid:83332(myctu)|taxid:83332("Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)")	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0471"(MINT)	intact:EBI-25767827|imex:IM-28235-265	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	go:"GO:0003677"(DNA binding)|go:"GO:0005618"(cell wall)|go:"GO:0005886"(plasma membrane)|go:"GO:0052170"(suppression by symbiont of host innate immune response)|mint:P9WJB9|refseq:NP_218397.1|refseq:WP_003399988.1|interpro:IPR036894|interpro:IPR004401(Conserved hypothetical protein CHP00103)	refseq:NP_919329.2|ensembl:ENSMUSG00000024773(gene)|ensembl:ENSMUST00000045351(transcript)|go:"GO:0000045"(autophagosome assembly)|go:"GO:0000407"(phagophore assembly site)|go:"GO:0000422"(autophagy of mitochondrion)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005811"(lipid droplet)|go:"GO:0019898"(extrinsic component of membrane)|go:"GO:0032266"(phosphatidylinositol-3-phosphate binding)|go:"GO:0034045"(phagophore assembly site membrane)|go:"GO:0034727"(piecemeal microautophagy of the nucleus)|go:"GO:0044805"(late nucleophagy)|go:"GO:0061709"(reticulophagy)|interpro:IPR015412(ATG2, C-terminal)|interpro:IPR026849|interpro:IPR026854|mint:Q6P4T0	-	-	-	figure legend:ST5|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2020/07/08	2020/08/14	rogid:BspTx2RZuhJaQ319NBDIyOreqfE83332	rogid:OORsj2CMXtjK9qGZ9EqzVQgyYsk10090	rigid:Z1GnLWnD63/OWYUxfPBjXr5ijDw	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P9WK51	uniprotkb:Q6P4T0	intact:EBI-25767833|uniprotkb:L0T6D1|uniprotkb:Q11013	intact:EBI-11065106|uniprotkb:Q6PHN0|uniprotkb:Q6ZQC4|uniprotkb:Q3U9I1|uniprotkb:Q8R213|ensembl:ENSMUSP00000046412	psi-mi:lprd_myctu(display_long)|uniprotkb:lprD(gene name)|psi-mi:lprD(display_short)|uniprotkb:MTCY02B10.07c(orf name)|uniprotkb:Rv1343c(locus name)	psi-mi:atg2a_mouse(display_long)|uniprotkb:Atg2a(gene name)|psi-mi:Atg2a(display_short)|uniprotkb:Kiaa0404(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2018)	doi:10.1093/nar/gkx1173|imex:IM-28235|pubmed:29165646	taxid:83332(myctu)|taxid:83332("Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)")	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0471"(MINT)	intact:EBI-25767845|imex:IM-28235-105	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	go:"GO:0005886"(plasma membrane)|go:"GO:0016021"(integral component of membrane)|mint:P9WK51|refseq:NP_215859.1|refseq:WP_003898833.1	refseq:NP_919329.2|ensembl:ENSMUSG00000024773(gene)|ensembl:ENSMUST00000045351(transcript)|go:"GO:0000045"(autophagosome assembly)|go:"GO:0000407"(phagophore assembly site)|go:"GO:0000422"(autophagy of mitochondrion)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005811"(lipid droplet)|go:"GO:0019898"(extrinsic component of membrane)|go:"GO:0032266"(phosphatidylinositol-3-phosphate binding)|go:"GO:0034045"(phagophore assembly site membrane)|go:"GO:0034727"(piecemeal microautophagy of the nucleus)|go:"GO:0044805"(late nucleophagy)|go:"GO:0061709"(reticulophagy)|interpro:IPR015412(ATG2, C-terminal)|interpro:IPR026849|interpro:IPR026854|mint:Q6P4T0	-	-	-	figure legend:ST5|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2020/07/08	2020/08/14	rogid:QGgZnt1zIKg1cEke5AZWZKM7Za483332	rogid:OORsj2CMXtjK9qGZ9EqzVQgyYsk10090	rigid:+U+pfBCVaJ4by8wvFDePlLNGQbE	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:I6Y946	uniprotkb:Q6P4T0	intact:EBI-25767727	intact:EBI-11065106|uniprotkb:Q6PHN0|uniprotkb:Q6ZQC4|uniprotkb:Q3U9I1|uniprotkb:Q8R213|ensembl:ENSMUSP00000046412	psi-mi:i6y946_myctu(display_long)|uniprotkb:Rv0925c(locus name)	psi-mi:atg2a_mouse(display_long)|uniprotkb:Atg2a(gene name)|psi-mi:Atg2a(display_short)|uniprotkb:Kiaa0404(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2018)	doi:10.1093/nar/gkx1173|imex:IM-28235|pubmed:29165646	taxid:83332(myctu)|taxid:83332("Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)")	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0471"(MINT)	intact:EBI-25767851|imex:IM-28235-267	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	go:"GO:0016491"(oxidoreductase activity)|mint:I6Y946|refseq:NP_215440.1|refseq:WP_003404764.1|interpro:IPR029039|interpro:IPR005025(NADPH-dependent FMN reductase)	refseq:NP_919329.2|ensembl:ENSMUSG00000024773(gene)|ensembl:ENSMUST00000045351(transcript)|go:"GO:0000045"(autophagosome assembly)|go:"GO:0000407"(phagophore assembly site)|go:"GO:0000422"(autophagy of mitochondrion)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005811"(lipid droplet)|go:"GO:0019898"(extrinsic component of membrane)|go:"GO:0032266"(phosphatidylinositol-3-phosphate binding)|go:"GO:0034045"(phagophore assembly site membrane)|go:"GO:0034727"(piecemeal microautophagy of the nucleus)|go:"GO:0044805"(late nucleophagy)|go:"GO:0061709"(reticulophagy)|interpro:IPR015412(ATG2, C-terminal)|interpro:IPR026849|interpro:IPR026854|mint:Q6P4T0	-	-	-	figure legend:ST5|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2020/07/08	2020/08/14	rogid:JOW06LtizimdrjJdMmMnM9ru8n083332	rogid:OORsj2CMXtjK9qGZ9EqzVQgyYsk10090	rigid:122NPgZeqt67kfRMXtImTEcGkZ8	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P9WHT9	uniprotkb:Q6P4T0	intact:EBI-7947958|uniprotkb:O33245|intact:MINT-7985947|uniprotkb:Q7D7I2|uniprotkb:L0T8V8	intact:EBI-11065106|uniprotkb:Q6PHN0|uniprotkb:Q6ZQC4|uniprotkb:Q3U9I1|uniprotkb:Q8R213|ensembl:ENSMUSP00000046412	psi-mi:psb_myctu(display_long)|uniprotkb:Proteasome core protein PrcB(gene name synonym)|uniprotkb:Rv2110c(locus name)|uniprotkb:prcB(gene name)|psi-mi:prcB(display_short)|uniprotkb:20S proteasome beta subunit(gene name synonym)	psi-mi:atg2a_mouse(display_long)|uniprotkb:Atg2a(gene name)|psi-mi:Atg2a(display_short)|uniprotkb:Kiaa0404(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2018)	doi:10.1093/nar/gkx1173|imex:IM-28235|pubmed:29165646	taxid:83332(myctu)|taxid:83332("Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)")	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0471"(MINT)	intact:EBI-25767857|imex:IM-28235-45	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	interpro:IPR029055|refseq:WP_003411023.1|interpro:IPR001353(20S proteasome, A and B subunits)|refseq:NP_216626.1|interpro:IPR023333|interpro:IPR022483|mint:P9WHT9|go:"GO:0004298"(threonine-type endopeptidase activity)|go:"GO:0005576"(extracellular region)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0010498"(proteasomal protein catabolic process)|go:"GO:0019773"(proteasome core complex, alpha-subunit complex)|go:"GO:0019774"(proteasome core complex, beta-subunit complex)|go:"GO:0019941"(modification-dependent protein catabolic process)|go:"GO:0030682"(mitigation of host defenses by symbiont)|go:"GO:0035375"(zymogen binding)|go:"GO:0051603"(proteolysis involved in cellular protein catabolic process)|rcsb pdb:2FHG|rcsb pdb:2FHH|rcsb pdb:2JAY|rcsb pdb:3H6F|rcsb pdb:3H6I|rcsb pdb:3HF9|rcsb pdb:3HFA|rcsb pdb:3KRD|rcsb pdb:3MFE|rcsb pdb:3MI0|rcsb pdb:3MKA|rcsb pdb:5LZP|rcsb pdb:5THO|rcsb pdb:5TRG|rcsb pdb:5TRR|rcsb pdb:5TRS|rcsb pdb:5TRY|rcsb pdb:5TS0|rcsb pdb:6BGL|rcsb pdb:6BGO|rcsb pdb:6OCW|rcsb pdb:6OCZ|rcsb pdb:6ODE	refseq:NP_919329.2|ensembl:ENSMUSG00000024773(gene)|ensembl:ENSMUST00000045351(transcript)|go:"GO:0000045"(autophagosome assembly)|go:"GO:0000407"(phagophore assembly site)|go:"GO:0000422"(autophagy of mitochondrion)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005811"(lipid droplet)|go:"GO:0019898"(extrinsic component of membrane)|go:"GO:0032266"(phosphatidylinositol-3-phosphate binding)|go:"GO:0034045"(phagophore assembly site membrane)|go:"GO:0034727"(piecemeal microautophagy of the nucleus)|go:"GO:0044805"(late nucleophagy)|go:"GO:0061709"(reticulophagy)|interpro:IPR015412(ATG2, C-terminal)|interpro:IPR026849|interpro:IPR026854|mint:Q6P4T0	-	crc64:3FC3FCD81231E129|comment:mint	-	figure legend:ST5|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2020/07/08	2020/08/14	rogid:hQ8Eci/BIL/quaWNhklTdFRPHDI83332	rogid:OORsj2CMXtjK9qGZ9EqzVQgyYsk10090	rigid:8kD+vqHFeizRTj8LWWeNEMdn4Zo	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:O50440	uniprotkb:Q6P4T0	intact:EBI-25767742|uniprotkb:I6XXB2|uniprotkb:L0T7J5	intact:EBI-11065106|uniprotkb:Q6PHN0|uniprotkb:Q6ZQC4|uniprotkb:Q3U9I1|uniprotkb:Q8R213|ensembl:ENSMUSP00000046412	psi-mi:chp2_myctu(display_long)|uniprotkb:chp2(gene name)|psi-mi:chp2(display_short)|uniprotkb:LH57_06500(orf name)|uniprotkb:P425_01234(orf name)|uniprotkb:Rv1184c(locus name)|uniprotkb:RVBD_1184c(locus name)	psi-mi:atg2a_mouse(display_long)|uniprotkb:Atg2a(gene name)|psi-mi:Atg2a(display_short)|uniprotkb:Kiaa0404(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2018)	doi:10.1093/nar/gkx1173|imex:IM-28235|pubmed:29165646	taxid:83332(myctu)|taxid:83332("Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)")	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0471"(MINT)	intact:EBI-25767863|imex:IM-28235-47	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	go:"GO:0005886"(plasma membrane)|go:"GO:0006629"(lipid metabolic process)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016746"(acyltransferase activity)|go:"GO:0005618"(cell wall)|mint:O50440|refseq:NP_215700.1|refseq:WP_003406195.1|interpro:IPR013228(PE-PPE, C-terminal)	refseq:NP_919329.2|ensembl:ENSMUSG00000024773(gene)|ensembl:ENSMUST00000045351(transcript)|go:"GO:0000045"(autophagosome assembly)|go:"GO:0000407"(phagophore assembly site)|go:"GO:0000422"(autophagy of mitochondrion)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005811"(lipid droplet)|go:"GO:0019898"(extrinsic component of membrane)|go:"GO:0032266"(phosphatidylinositol-3-phosphate binding)|go:"GO:0034045"(phagophore assembly site membrane)|go:"GO:0034727"(piecemeal microautophagy of the nucleus)|go:"GO:0044805"(late nucleophagy)|go:"GO:0061709"(reticulophagy)|interpro:IPR015412(ATG2, C-terminal)|interpro:IPR026849|interpro:IPR026854|mint:Q6P4T0	-	-	-	figure legend:ST5|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2020/07/08	2020/08/14	rogid:IXzYfb7UxFgqBXPZ6NZHLy3hdTc83332	rogid:OORsj2CMXtjK9qGZ9EqzVQgyYsk10090	rigid:0HD7PdRbicbg9paLtz2L8iL2TaI	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:O53319	uniprotkb:Q6P4T0	intact:EBI-25767766|uniprotkb:I6X6K2|uniprotkb:L0TEH7	intact:EBI-11065106|uniprotkb:Q6PHN0|uniprotkb:Q6ZQC4|uniprotkb:Q3U9I1|uniprotkb:Q8R213|ensembl:ENSMUSP00000046412	psi-mi:o53319_myctu(display_long)|uniprotkb:Rv3169(locus name)	psi-mi:atg2a_mouse(display_long)|uniprotkb:Atg2a(gene name)|psi-mi:Atg2a(display_short)|uniprotkb:Kiaa0404(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2018)	doi:10.1093/nar/gkx1173|imex:IM-28235|pubmed:29165646	taxid:83332(myctu)|taxid:83332("Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)")	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0471"(MINT)	intact:EBI-25767869|imex:IM-28235-49	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	go:"GO:0005886"(plasma membrane)|mint:O53319|refseq:NP_217685.1|refseq:WP_003416605.1	refseq:NP_919329.2|ensembl:ENSMUSG00000024773(gene)|ensembl:ENSMUST00000045351(transcript)|go:"GO:0000045"(autophagosome assembly)|go:"GO:0000407"(phagophore assembly site)|go:"GO:0000422"(autophagy of mitochondrion)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005811"(lipid droplet)|go:"GO:0019898"(extrinsic component of membrane)|go:"GO:0032266"(phosphatidylinositol-3-phosphate binding)|go:"GO:0034045"(phagophore assembly site membrane)|go:"GO:0034727"(piecemeal microautophagy of the nucleus)|go:"GO:0044805"(late nucleophagy)|go:"GO:0061709"(reticulophagy)|interpro:IPR015412(ATG2, C-terminal)|interpro:IPR026849|interpro:IPR026854|mint:Q6P4T0	-	-	-	figure legend:ST5|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2020/07/08	2020/08/14	rogid:Gd1O5B5qTAQflXzn9MR+6fgqvDs83332	rogid:OORsj2CMXtjK9qGZ9EqzVQgyYsk10090	rigid:3rdQVUrRlozFoZ/7h3JQlHn9HyU	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:O07422	uniprotkb:Q8CDJ3	intact:EBI-25767563|uniprotkb:F2GLX6|uniprotkb:I6Y302|uniprotkb:Q7DAB9	intact:EBI-3506699|uniprotkb:Q69ZY1|uniprotkb:Q6PFY6|uniprotkb:Q8C6N0|uniprotkb:Q8R3M3|ensembl:ENSMUSP00000039047|ensembl:ENSMUSP00000153718	psi-mi:o07422_myctu(display_long)|uniprotkb:Rv0178(locus name)	psi-mi:bakor_mouse(display_long)|uniprotkb:Atg14(gene name)|psi-mi:Atg14(display_short)|uniprotkb:D14Ertd436e(gene name synonym)|uniprotkb:Kiaa0831(gene name synonym)|uniprotkb:Autophagy-related protein 14-like protein(gene name synonym)|uniprotkb:Atg14L(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2018)	doi:10.1093/nar/gkx1173|imex:IM-28235|pubmed:29165646	taxid:83332(myctu)|taxid:83332("Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)")	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0471"(MINT)	intact:EBI-25767576|imex:IM-28235-1	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	go:"GO:0005576"(extracellular region)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0051701"(biological process involved in interaction with host)|mint:O07422|refseq:NP_214692.1|refseq:WP_003899844.1	refseq:NP_766187.1|ensembl:ENSMUSG00000037526(gene)|ensembl:ENSMUST00000042988(transcript)|ensembl:ENSMUST00000226299(transcript)|go:"GO:0000045"(autophagosome assembly)|go:"GO:0000421"(autophagosome membrane)|go:"GO:0000423"(mitophagy)|go:"GO:0001932"(regulation of protein phosphorylation)|go:"GO:0001933"(negative regulation of protein phosphorylation)|go:"GO:0001934"(positive regulation of protein phosphorylation)|go:"GO:0005776"(autophagosome)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005930"(axoneme)|go:"GO:0006914"(autophagy)|go:"GO:0008333"(endosome to lysosome transport)|go:"GO:0009267"(cellular response to starvation)|go:"GO:0010608"(posttranscriptional regulation of gene expression)|go:"GO:0016236"(macroautophagy)|go:"GO:0016240"(autophagosome membrane docking)|go:"GO:0034045"(phagophore assembly site membrane)|go:"GO:0035032"(phosphatidylinositol 3-kinase complex, class III)|go:"GO:0042149"(cellular response to glucose starvation)|go:"GO:0043552"(positive regulation of phosphatidylinositol 3-kinase activity)|go:"GO:0044233"(mitochondria-associated endoplasmic reticulum membrane)|go:"GO:0045335"(phagocytic vesicle)|go:"GO:0051020"(GTPase binding)|go:"GO:0090207"(regulation of triglyceride metabolic process)|go:"GO:0097629"(extrinsic component of omegasome membrane)|go:"GO:0097632"(extrinsic component of phagophore assembly site membrane)|go:"GO:0098780"(response to mitochondrial depolarisation)|interpro:IPR018791|mint:Q8CDJ3|reactome:R-MMU-1632852|dip:DIP-60849N	-	-	-	figure legend:ST5|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2020/07/08	2020/08/14	rogid:lGOg72Osvz8819m674JzGUcHEj483332	rogid:Ha+zYY4aNPLZH0LQPz9s1SSK9R410090	rigid:Hjd0C6uuGiTrq8JE9CEjBxiHGw0	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:O07422	uniprotkb:Q80XK6	intact:EBI-25767563|uniprotkb:F2GLX6|uniprotkb:I6Y302|uniprotkb:Q7DAB9	intact:EBI-11566520|uniprotkb:Q9CWK6|uniprotkb:Q8BIV0|uniprotkb:Q8BIQ4|uniprotkb:A0PJL7|uniprotkb:Q8R1H5|ensembl:ENSMUSP00000037441	psi-mi:o07422_myctu(display_long)|uniprotkb:Rv0178(locus name)	psi-mi:atg2b_mouse(display_long)|uniprotkb:Atg2b(gene name)|psi-mi:Atg2b(display_short)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2018)	doi:10.1093/nar/gkx1173|imex:IM-28235|pubmed:29165646	taxid:83332(myctu)|taxid:83332("Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)")	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0471"(MINT)	intact:EBI-25767959|imex:IM-28235-229	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	go:"GO:0005576"(extracellular region)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0051701"(biological process involved in interaction with host)|mint:O07422|refseq:NP_214692.1|refseq:WP_003899844.1	refseq:NP_083930.5|ensembl:ENSMUSG00000041341(gene)|ensembl:ENSMUST00000041055(transcript)|go:"GO:0000045"(autophagosome assembly)|go:"GO:0000407"(phagophore assembly site)|go:"GO:0000422"(autophagy of mitochondrion)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005811"(lipid droplet)|go:"GO:0019898"(extrinsic component of membrane)|go:"GO:0032266"(phosphatidylinositol-3-phosphate binding)|go:"GO:0034045"(phagophore assembly site membrane)|go:"GO:0034727"(piecemeal microautophagy of the nucleus)|go:"GO:0044805"(late nucleophagy)|go:"GO:0061709"(reticulophagy)|go:"GO:0120013"(lipid transfer activity)|interpro:IPR015412(ATG2, C-terminal)|interpro:IPR026849|interpro:IPR026854|mint:Q80XK6	-	-	-	figure legend:ST5|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2020/07/08	2020/08/14	rogid:lGOg72Osvz8819m674JzGUcHEj483332	rogid:jnUVUCip0mX6qajisFBvpNEqixE10090	rigid:drNRPNi9lLq0NICxWhv4zyI/gOc	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:O07177	uniprotkb:Q80XK6	intact:EBI-25767633|uniprotkb:L0T5L4	intact:EBI-11566520|uniprotkb:Q9CWK6|uniprotkb:Q8BIV0|uniprotkb:Q8BIQ4|uniprotkb:A0PJL7|uniprotkb:Q8R1H5|ensembl:ENSMUSP00000037441	psi-mi:mak1_myctu(display_long)|uniprotkb:mak(gene name)|psi-mi:mak(display_short)|uniprotkb:Maltose-1-phosphate synthase(gene name synonym)|uniprotkb:Rv0127(locus name)	psi-mi:atg2b_mouse(display_long)|uniprotkb:Atg2b(gene name)|psi-mi:Atg2b(display_short)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2018)	doi:10.1093/nar/gkx1173|imex:IM-28235|pubmed:29165646	taxid:83332(myctu)|taxid:83332("Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)")	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0471"(MINT)	intact:EBI-25767875|imex:IM-28235-183	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	go:"GO:0005978"(glycogen biosynthetic process)|go:"GO:0005992"(trehalose biosynthetic process)|go:"GO:0016301"(kinase activity)|go:"GO:0046835"(carbohydrate phosphorylation)|rcsb pdb:4O7O|rcsb pdb:4O7P|go:"GO:0005524"(ATP binding)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|mint:O07177|refseq:NP_214641.1|refseq:WP_003916610.1|interpro:IPR011009(Protein kinase-like)|interpro:IPR040999	refseq:NP_083930.5|ensembl:ENSMUSG00000041341(gene)|ensembl:ENSMUST00000041055(transcript)|go:"GO:0000045"(autophagosome assembly)|go:"GO:0000407"(phagophore assembly site)|go:"GO:0000422"(autophagy of mitochondrion)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005811"(lipid droplet)|go:"GO:0019898"(extrinsic component of membrane)|go:"GO:0032266"(phosphatidylinositol-3-phosphate binding)|go:"GO:0034045"(phagophore assembly site membrane)|go:"GO:0034727"(piecemeal microautophagy of the nucleus)|go:"GO:0044805"(late nucleophagy)|go:"GO:0061709"(reticulophagy)|go:"GO:0120013"(lipid transfer activity)|interpro:IPR015412(ATG2, C-terminal)|interpro:IPR026849|interpro:IPR026854|mint:Q80XK6	-	-	-	figure legend:ST5|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2020/07/08	2020/08/14	rogid:kpl6jZ4UbJUq/kfAlHBYpJAJV4E83332	rogid:jnUVUCip0mX6qajisFBvpNEqixE10090	rigid:GYvhKqYAI6lJcxTJMK6LF9AHP9c	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P9WIT1	uniprotkb:Q80XK6	intact:EBI-25767539|uniprotkb:L0TBU2|uniprotkb:Q50685|uniprotkb:Q7D7C5	intact:EBI-11566520|uniprotkb:Q9CWK6|uniprotkb:Q8BIV0|uniprotkb:Q8BIQ4|uniprotkb:A0PJL7|uniprotkb:Q8R1H5|ensembl:ENSMUSP00000037441	psi-mi:y2280_myctu(display_long)|uniprotkb:Rv2280(locus name)	psi-mi:atg2b_mouse(display_long)|uniprotkb:Atg2b(gene name)|psi-mi:Atg2b(display_short)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2018)	doi:10.1093/nar/gkx1173|imex:IM-28235|pubmed:29165646	taxid:83332(myctu)|taxid:83332("Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)")	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0471"(MINT)	intact:EBI-25767881|imex:IM-28235-225	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	go:"GO:0005618"(cell wall)|go:"GO:0005886"(plasma membrane)|go:"GO:0016491"(oxidoreductase activity)|go:"GO:0071949"(FAD binding)|interpro:IPR016169(CO dehydrogenase flavoprotein-like, FAD-binding, subdomain 2)|mint:P9WIT1|refseq:WP_003411690.1|interpro:IPR016166(FAD-binding, type 2)|interpro:IPR036318|interpro:IPR016164(FAD-linked oxidase-like, C-terminal)|interpro:IPR004113(FAD-linked oxidase, C-terminal)|interpro:IPR006094(FAD linked oxidase, N-terminal)|interpro:IPR016171(Vanillyl-alcohol oxidase, C-terminal subdomain 2)	refseq:NP_083930.5|ensembl:ENSMUSG00000041341(gene)|ensembl:ENSMUST00000041055(transcript)|go:"GO:0000045"(autophagosome assembly)|go:"GO:0000407"(phagophore assembly site)|go:"GO:0000422"(autophagy of mitochondrion)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005811"(lipid droplet)|go:"GO:0019898"(extrinsic component of membrane)|go:"GO:0032266"(phosphatidylinositol-3-phosphate binding)|go:"GO:0034045"(phagophore assembly site membrane)|go:"GO:0034727"(piecemeal microautophagy of the nucleus)|go:"GO:0044805"(late nucleophagy)|go:"GO:0061709"(reticulophagy)|go:"GO:0120013"(lipid transfer activity)|interpro:IPR015412(ATG2, C-terminal)|interpro:IPR026849|interpro:IPR026854|mint:Q80XK6	-	-	-	figure legend:ST5|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2020/07/08	2020/08/14	rogid:TvFI3uuw9zREl1q0DeWIsHmCSEk83332	rogid:jnUVUCip0mX6qajisFBvpNEqixE10090	rigid:6DxKMnlnJQdwnQVEOEG2P5j8Q5c	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q80XK6	uniprotkb:P9WNI7	intact:EBI-11566520|uniprotkb:Q9CWK6|uniprotkb:Q8BIV0|uniprotkb:Q8BIQ4|uniprotkb:A0PJL7|uniprotkb:Q8R1H5|ensembl:ENSMUSP00000037441	intact:EBI-9027314|uniprotkb:P95242|uniprotkb:L0T9C9	psi-mi:atg2b_mouse(display_long)|uniprotkb:Atg2b(gene name)|psi-mi:Atg2b(display_short)	psi-mi:esxo_myctu(display_long)|uniprotkb:esxO(gene name)|psi-mi:esxO(display_short)|uniprotkb:MTCY98.15c(orf name)|uniprotkb:Rv2346c(locus name)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2018)	doi:10.1093/nar/gkx1173|imex:IM-28235|pubmed:29165646	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:83332(myctu)|taxid:83332("Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)")	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0471"(MINT)	intact:EBI-25767887|imex:IM-28235-85	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_083930.5|ensembl:ENSMUSG00000041341(gene)|ensembl:ENSMUST00000041055(transcript)|go:"GO:0000045"(autophagosome assembly)|go:"GO:0000407"(phagophore assembly site)|go:"GO:0000422"(autophagy of mitochondrion)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005811"(lipid droplet)|go:"GO:0019898"(extrinsic component of membrane)|go:"GO:0032266"(phosphatidylinositol-3-phosphate binding)|go:"GO:0034045"(phagophore assembly site membrane)|go:"GO:0034727"(piecemeal microautophagy of the nucleus)|go:"GO:0044805"(late nucleophagy)|go:"GO:0061709"(reticulophagy)|go:"GO:0120013"(lipid transfer activity)|interpro:IPR015412(ATG2, C-terminal)|interpro:IPR026849|interpro:IPR026854|mint:Q80XK6	mint:P9WNI7|interpro:IPR036689|interpro:IPR009416(Protein of unknown function DUF1066)|interpro:IPR010310(Protein of unknown function DUF909)|refseq:NP_216862.1|refseq:WP_003899283.1|go:"GO:0005576"(extracellular region)|go:"GO:0005618"(cell wall)|go:"GO:0005886"(plasma membrane)|rcsb pdb:3OGI|rcsb pdb:4GZR	-	-	-	figure legend:ST5|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2020/07/08	2020/08/14	rogid:jnUVUCip0mX6qajisFBvpNEqixE10090	rogid:jYoNmHY+G6+S39CX1qRFCxjy0xw83332	rigid:vZfSWQeJD0B//sPkchswU4OPMS0	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P9WJB9	uniprotkb:Q80XK6	intact:EBI-25767670|uniprotkb:L0TE21|uniprotkb:O69744|uniprotkb:Q7D4P0	intact:EBI-11566520|uniprotkb:Q9CWK6|uniprotkb:Q8BIV0|uniprotkb:Q8BIQ4|uniprotkb:A0PJL7|uniprotkb:Q8R1H5|ensembl:ENSMUSP00000037441	psi-mi:espl_myctu(display_long)|uniprotkb:espL(gene name)|psi-mi:espL(display_short)|uniprotkb:Rv3880c(locus name)	psi-mi:atg2b_mouse(display_long)|uniprotkb:Atg2b(gene name)|psi-mi:Atg2b(display_short)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2018)	doi:10.1093/nar/gkx1173|imex:IM-28235|pubmed:29165646	taxid:83332(myctu)|taxid:83332("Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)")	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0471"(MINT)	intact:EBI-25767893|imex:IM-28235-305	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	go:"GO:0003677"(DNA binding)|go:"GO:0005618"(cell wall)|go:"GO:0005886"(plasma membrane)|go:"GO:0052170"(suppression by symbiont of host innate immune response)|mint:P9WJB9|refseq:NP_218397.1|refseq:WP_003399988.1|interpro:IPR036894|interpro:IPR004401(Conserved hypothetical protein CHP00103)	refseq:NP_083930.5|ensembl:ENSMUSG00000041341(gene)|ensembl:ENSMUST00000041055(transcript)|go:"GO:0000045"(autophagosome assembly)|go:"GO:0000407"(phagophore assembly site)|go:"GO:0000422"(autophagy of mitochondrion)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005811"(lipid droplet)|go:"GO:0019898"(extrinsic component of membrane)|go:"GO:0032266"(phosphatidylinositol-3-phosphate binding)|go:"GO:0034045"(phagophore assembly site membrane)|go:"GO:0034727"(piecemeal microautophagy of the nucleus)|go:"GO:0044805"(late nucleophagy)|go:"GO:0061709"(reticulophagy)|go:"GO:0120013"(lipid transfer activity)|interpro:IPR015412(ATG2, C-terminal)|interpro:IPR026849|interpro:IPR026854|mint:Q80XK6	-	-	-	figure legend:ST5|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2020/07/08	2020/08/14	rogid:BspTx2RZuhJaQ319NBDIyOreqfE83332	rogid:jnUVUCip0mX6qajisFBvpNEqixE10090	rigid:AuFmhD8/NpS5QCdF03/2whnwwjk	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:O07422	uniprotkb:Q80XK6	intact:EBI-25767563|uniprotkb:F2GLX6|uniprotkb:I6Y302|uniprotkb:Q7DAB9	intact:EBI-11566520|uniprotkb:Q9CWK6|uniprotkb:Q8BIV0|uniprotkb:Q8BIQ4|uniprotkb:A0PJL7|uniprotkb:Q8R1H5|ensembl:ENSMUSP00000037441	psi-mi:o07422_myctu(display_long)|uniprotkb:Rv0178(locus name)	psi-mi:atg2b_mouse(display_long)|uniprotkb:Atg2b(gene name)|psi-mi:Atg2b(display_short)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2018)	doi:10.1093/nar/gkx1173|imex:IM-28235|pubmed:29165646	taxid:83332(myctu)|taxid:83332("Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)")	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0471"(MINT)	intact:EBI-25767899|imex:IM-28235-269	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	go:"GO:0005576"(extracellular region)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0051701"(biological process involved in interaction with host)|mint:O07422|refseq:NP_214692.1|refseq:WP_003899844.1	refseq:NP_083930.5|ensembl:ENSMUSG00000041341(gene)|ensembl:ENSMUST00000041055(transcript)|go:"GO:0000045"(autophagosome assembly)|go:"GO:0000407"(phagophore assembly site)|go:"GO:0000422"(autophagy of mitochondrion)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005811"(lipid droplet)|go:"GO:0019898"(extrinsic component of membrane)|go:"GO:0032266"(phosphatidylinositol-3-phosphate binding)|go:"GO:0034045"(phagophore assembly site membrane)|go:"GO:0034727"(piecemeal microautophagy of the nucleus)|go:"GO:0044805"(late nucleophagy)|go:"GO:0061709"(reticulophagy)|go:"GO:0120013"(lipid transfer activity)|interpro:IPR015412(ATG2, C-terminal)|interpro:IPR026849|interpro:IPR026854|mint:Q80XK6	-	-	-	figure legend:ST5|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2020/07/08	2020/08/14	rogid:lGOg72Osvz8819m674JzGUcHEj483332	rogid:jnUVUCip0mX6qajisFBvpNEqixE10090	rigid:drNRPNi9lLq0NICxWhv4zyI/gOc	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:I6Y946	uniprotkb:Q80XK6	intact:EBI-25767727	intact:EBI-11566520|uniprotkb:Q9CWK6|uniprotkb:Q8BIV0|uniprotkb:Q8BIQ4|uniprotkb:A0PJL7|uniprotkb:Q8R1H5|ensembl:ENSMUSP00000037441	psi-mi:i6y946_myctu(display_long)|uniprotkb:Rv0925c(locus name)	psi-mi:atg2b_mouse(display_long)|uniprotkb:Atg2b(gene name)|psi-mi:Atg2b(display_short)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2018)	doi:10.1093/nar/gkx1173|imex:IM-28235|pubmed:29165646	taxid:83332(myctu)|taxid:83332("Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)")	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0471"(MINT)	intact:EBI-25767905|imex:IM-28235-307	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	go:"GO:0016491"(oxidoreductase activity)|mint:I6Y946|refseq:NP_215440.1|refseq:WP_003404764.1|interpro:IPR029039|interpro:IPR005025(NADPH-dependent FMN reductase)	refseq:NP_083930.5|ensembl:ENSMUSG00000041341(gene)|ensembl:ENSMUST00000041055(transcript)|go:"GO:0000045"(autophagosome assembly)|go:"GO:0000407"(phagophore assembly site)|go:"GO:0000422"(autophagy of mitochondrion)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005811"(lipid droplet)|go:"GO:0019898"(extrinsic component of membrane)|go:"GO:0032266"(phosphatidylinositol-3-phosphate binding)|go:"GO:0034045"(phagophore assembly site membrane)|go:"GO:0034727"(piecemeal microautophagy of the nucleus)|go:"GO:0044805"(late nucleophagy)|go:"GO:0061709"(reticulophagy)|go:"GO:0120013"(lipid transfer activity)|interpro:IPR015412(ATG2, C-terminal)|interpro:IPR026849|interpro:IPR026854|mint:Q80XK6	-	-	-	figure legend:ST5|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2020/07/08	2020/08/14	rogid:JOW06LtizimdrjJdMmMnM9ru8n083332	rogid:jnUVUCip0mX6qajisFBvpNEqixE10090	rigid:FljHBpawKUDeH/W4Ags3VGWjQn8	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P9WHT9	uniprotkb:Q80XK6	intact:EBI-7947958|uniprotkb:O33245|intact:MINT-7985947|uniprotkb:Q7D7I2|uniprotkb:L0T8V8	intact:EBI-11566520|uniprotkb:Q9CWK6|uniprotkb:Q8BIV0|uniprotkb:Q8BIQ4|uniprotkb:A0PJL7|uniprotkb:Q8R1H5|ensembl:ENSMUSP00000037441	psi-mi:psb_myctu(display_long)|uniprotkb:Proteasome core protein PrcB(gene name synonym)|uniprotkb:Rv2110c(locus name)|uniprotkb:prcB(gene name)|psi-mi:prcB(display_short)|uniprotkb:20S proteasome beta subunit(gene name synonym)	psi-mi:atg2b_mouse(display_long)|uniprotkb:Atg2b(gene name)|psi-mi:Atg2b(display_short)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2018)	doi:10.1093/nar/gkx1173|imex:IM-28235|pubmed:29165646	taxid:83332(myctu)|taxid:83332("Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)")	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0471"(MINT)	intact:EBI-25767911|imex:IM-28235-9	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	interpro:IPR029055|refseq:WP_003411023.1|interpro:IPR001353(20S proteasome, A and B subunits)|refseq:NP_216626.1|interpro:IPR023333|interpro:IPR022483|mint:P9WHT9|go:"GO:0004298"(threonine-type endopeptidase activity)|go:"GO:0005576"(extracellular region)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0010498"(proteasomal protein catabolic process)|go:"GO:0019773"(proteasome core complex, alpha-subunit complex)|go:"GO:0019774"(proteasome core complex, beta-subunit complex)|go:"GO:0019941"(modification-dependent protein catabolic process)|go:"GO:0030682"(mitigation of host defenses by symbiont)|go:"GO:0035375"(zymogen binding)|go:"GO:0051603"(proteolysis involved in cellular protein catabolic process)|rcsb pdb:2FHG|rcsb pdb:2FHH|rcsb pdb:2JAY|rcsb pdb:3H6F|rcsb pdb:3H6I|rcsb pdb:3HF9|rcsb pdb:3HFA|rcsb pdb:3KRD|rcsb pdb:3MFE|rcsb pdb:3MI0|rcsb pdb:3MKA|rcsb pdb:5LZP|rcsb pdb:5THO|rcsb pdb:5TRG|rcsb pdb:5TRR|rcsb pdb:5TRS|rcsb pdb:5TRY|rcsb pdb:5TS0|rcsb pdb:6BGL|rcsb pdb:6BGO|rcsb pdb:6OCW|rcsb pdb:6OCZ|rcsb pdb:6ODE	refseq:NP_083930.5|ensembl:ENSMUSG00000041341(gene)|ensembl:ENSMUST00000041055(transcript)|go:"GO:0000045"(autophagosome assembly)|go:"GO:0000407"(phagophore assembly site)|go:"GO:0000422"(autophagy of mitochondrion)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005811"(lipid droplet)|go:"GO:0019898"(extrinsic component of membrane)|go:"GO:0032266"(phosphatidylinositol-3-phosphate binding)|go:"GO:0034045"(phagophore assembly site membrane)|go:"GO:0034727"(piecemeal microautophagy of the nucleus)|go:"GO:0044805"(late nucleophagy)|go:"GO:0061709"(reticulophagy)|go:"GO:0120013"(lipid transfer activity)|interpro:IPR015412(ATG2, C-terminal)|interpro:IPR026849|interpro:IPR026854|mint:Q80XK6	-	crc64:3FC3FCD81231E129|comment:mint	-	figure legend:ST5|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2020/07/08	2020/08/14	rogid:hQ8Eci/BIL/quaWNhklTdFRPHDI83332	rogid:jnUVUCip0mX6qajisFBvpNEqixE10090	rigid:2rM0bGg/NqgFHNKzI4RJGxkVVFA	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:O07177	uniprotkb:Q80XK6	intact:EBI-25767633|uniprotkb:L0T5L4	intact:EBI-11566520|uniprotkb:Q9CWK6|uniprotkb:Q8BIV0|uniprotkb:Q8BIQ4|uniprotkb:A0PJL7|uniprotkb:Q8R1H5|ensembl:ENSMUSP00000037441	psi-mi:mak1_myctu(display_long)|uniprotkb:mak(gene name)|psi-mi:mak(display_short)|uniprotkb:Maltose-1-phosphate synthase(gene name synonym)|uniprotkb:Rv0127(locus name)	psi-mi:atg2b_mouse(display_long)|uniprotkb:Atg2b(gene name)|psi-mi:Atg2b(display_short)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2018)	doi:10.1093/nar/gkx1173|imex:IM-28235|pubmed:29165646	taxid:83332(myctu)|taxid:83332("Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)")	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0471"(MINT)	intact:EBI-25767917|imex:IM-28235-271	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	go:"GO:0005978"(glycogen biosynthetic process)|go:"GO:0005992"(trehalose biosynthetic process)|go:"GO:0016301"(kinase activity)|go:"GO:0046835"(carbohydrate phosphorylation)|rcsb pdb:4O7O|rcsb pdb:4O7P|go:"GO:0005524"(ATP binding)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|mint:O07177|refseq:NP_214641.1|refseq:WP_003916610.1|interpro:IPR011009(Protein kinase-like)|interpro:IPR040999	refseq:NP_083930.5|ensembl:ENSMUSG00000041341(gene)|ensembl:ENSMUST00000041055(transcript)|go:"GO:0000045"(autophagosome assembly)|go:"GO:0000407"(phagophore assembly site)|go:"GO:0000422"(autophagy of mitochondrion)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005811"(lipid droplet)|go:"GO:0019898"(extrinsic component of membrane)|go:"GO:0032266"(phosphatidylinositol-3-phosphate binding)|go:"GO:0034045"(phagophore assembly site membrane)|go:"GO:0034727"(piecemeal microautophagy of the nucleus)|go:"GO:0044805"(late nucleophagy)|go:"GO:0061709"(reticulophagy)|go:"GO:0120013"(lipid transfer activity)|interpro:IPR015412(ATG2, C-terminal)|interpro:IPR026849|interpro:IPR026854|mint:Q80XK6	-	-	-	figure legend:ST5|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2020/07/08	2020/08/14	rogid:kpl6jZ4UbJUq/kfAlHBYpJAJV4E83332	rogid:jnUVUCip0mX6qajisFBvpNEqixE10090	rigid:GYvhKqYAI6lJcxTJMK6LF9AHP9c	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P9WIT1	uniprotkb:Q80XK6	intact:EBI-25767539|uniprotkb:L0TBU2|uniprotkb:Q50685|uniprotkb:Q7D7C5	intact:EBI-11566520|uniprotkb:Q9CWK6|uniprotkb:Q8BIV0|uniprotkb:Q8BIQ4|uniprotkb:A0PJL7|uniprotkb:Q8R1H5|ensembl:ENSMUSP00000037441	psi-mi:y2280_myctu(display_long)|uniprotkb:Rv2280(locus name)	psi-mi:atg2b_mouse(display_long)|uniprotkb:Atg2b(gene name)|psi-mi:Atg2b(display_short)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2018)	doi:10.1093/nar/gkx1173|imex:IM-28235|pubmed:29165646	taxid:83332(myctu)|taxid:83332("Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)")	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0471"(MINT)	intact:EBI-25767923|imex:IM-28235-107	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	go:"GO:0005618"(cell wall)|go:"GO:0005886"(plasma membrane)|go:"GO:0016491"(oxidoreductase activity)|go:"GO:0071949"(FAD binding)|interpro:IPR016169(CO dehydrogenase flavoprotein-like, FAD-binding, subdomain 2)|mint:P9WIT1|refseq:WP_003411690.1|interpro:IPR016166(FAD-binding, type 2)|interpro:IPR036318|interpro:IPR016164(FAD-linked oxidase-like, C-terminal)|interpro:IPR004113(FAD-linked oxidase, C-terminal)|interpro:IPR006094(FAD linked oxidase, N-terminal)|interpro:IPR016171(Vanillyl-alcohol oxidase, C-terminal subdomain 2)	refseq:NP_083930.5|ensembl:ENSMUSG00000041341(gene)|ensembl:ENSMUST00000041055(transcript)|go:"GO:0000045"(autophagosome assembly)|go:"GO:0000407"(phagophore assembly site)|go:"GO:0000422"(autophagy of mitochondrion)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005811"(lipid droplet)|go:"GO:0019898"(extrinsic component of membrane)|go:"GO:0032266"(phosphatidylinositol-3-phosphate binding)|go:"GO:0034045"(phagophore assembly site membrane)|go:"GO:0034727"(piecemeal microautophagy of the nucleus)|go:"GO:0044805"(late nucleophagy)|go:"GO:0061709"(reticulophagy)|go:"GO:0120013"(lipid transfer activity)|interpro:IPR015412(ATG2, C-terminal)|interpro:IPR026849|interpro:IPR026854|mint:Q80XK6	-	-	-	figure legend:ST5|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2020/07/08	2020/08/14	rogid:TvFI3uuw9zREl1q0DeWIsHmCSEk83332	rogid:jnUVUCip0mX6qajisFBvpNEqixE10090	rigid:6DxKMnlnJQdwnQVEOEG2P5j8Q5c	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:O07422	uniprotkb:Q80XK6	intact:EBI-25767563|uniprotkb:F2GLX6|uniprotkb:I6Y302|uniprotkb:Q7DAB9	intact:EBI-11566520|uniprotkb:Q9CWK6|uniprotkb:Q8BIV0|uniprotkb:Q8BIQ4|uniprotkb:A0PJL7|uniprotkb:Q8R1H5|ensembl:ENSMUSP00000037441	psi-mi:o07422_myctu(display_long)|uniprotkb:Rv0178(locus name)	psi-mi:atg2b_mouse(display_long)|uniprotkb:Atg2b(gene name)|psi-mi:Atg2b(display_short)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2018)	doi:10.1093/nar/gkx1173|imex:IM-28235|pubmed:29165646	taxid:83332(myctu)|taxid:83332("Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)")	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0471"(MINT)	intact:EBI-25767929|imex:IM-28235-121	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	go:"GO:0005576"(extracellular region)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0051701"(biological process involved in interaction with host)|mint:O07422|refseq:NP_214692.1|refseq:WP_003899844.1	refseq:NP_083930.5|ensembl:ENSMUSG00000041341(gene)|ensembl:ENSMUST00000041055(transcript)|go:"GO:0000045"(autophagosome assembly)|go:"GO:0000407"(phagophore assembly site)|go:"GO:0000422"(autophagy of mitochondrion)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005811"(lipid droplet)|go:"GO:0019898"(extrinsic component of membrane)|go:"GO:0032266"(phosphatidylinositol-3-phosphate binding)|go:"GO:0034045"(phagophore assembly site membrane)|go:"GO:0034727"(piecemeal microautophagy of the nucleus)|go:"GO:0044805"(late nucleophagy)|go:"GO:0061709"(reticulophagy)|go:"GO:0120013"(lipid transfer activity)|interpro:IPR015412(ATG2, C-terminal)|interpro:IPR026849|interpro:IPR026854|mint:Q80XK6	-	-	-	figure legend:ST5|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2020/07/08	2020/08/14	rogid:lGOg72Osvz8819m674JzGUcHEj483332	rogid:jnUVUCip0mX6qajisFBvpNEqixE10090	rigid:drNRPNi9lLq0NICxWhv4zyI/gOc	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:I6Y946	uniprotkb:Q80XK6	intact:EBI-25767727	intact:EBI-11566520|uniprotkb:Q9CWK6|uniprotkb:Q8BIV0|uniprotkb:Q8BIQ4|uniprotkb:A0PJL7|uniprotkb:Q8R1H5|ensembl:ENSMUSP00000037441	psi-mi:i6y946_myctu(display_long)|uniprotkb:Rv0925c(locus name)	psi-mi:atg2b_mouse(display_long)|uniprotkb:Atg2b(gene name)|psi-mi:Atg2b(display_short)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2018)	doi:10.1093/nar/gkx1173|imex:IM-28235|pubmed:29165646	taxid:83332(myctu)|taxid:83332("Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)")	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0471"(MINT)	intact:EBI-25767935|imex:IM-28235-123	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	go:"GO:0016491"(oxidoreductase activity)|mint:I6Y946|refseq:NP_215440.1|refseq:WP_003404764.1|interpro:IPR029039|interpro:IPR005025(NADPH-dependent FMN reductase)	refseq:NP_083930.5|ensembl:ENSMUSG00000041341(gene)|ensembl:ENSMUST00000041055(transcript)|go:"GO:0000045"(autophagosome assembly)|go:"GO:0000407"(phagophore assembly site)|go:"GO:0000422"(autophagy of mitochondrion)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005811"(lipid droplet)|go:"GO:0019898"(extrinsic component of membrane)|go:"GO:0032266"(phosphatidylinositol-3-phosphate binding)|go:"GO:0034045"(phagophore assembly site membrane)|go:"GO:0034727"(piecemeal microautophagy of the nucleus)|go:"GO:0044805"(late nucleophagy)|go:"GO:0061709"(reticulophagy)|go:"GO:0120013"(lipid transfer activity)|interpro:IPR015412(ATG2, C-terminal)|interpro:IPR026849|interpro:IPR026854|mint:Q80XK6	-	-	-	figure legend:ST5|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2020/07/08	2020/08/14	rogid:JOW06LtizimdrjJdMmMnM9ru8n083332	rogid:jnUVUCip0mX6qajisFBvpNEqixE10090	rigid:FljHBpawKUDeH/W4Ags3VGWjQn8	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:O53319	uniprotkb:Q80XK6	intact:EBI-25767766|uniprotkb:I6X6K2|uniprotkb:L0TEH7	intact:EBI-11566520|uniprotkb:Q9CWK6|uniprotkb:Q8BIV0|uniprotkb:Q8BIQ4|uniprotkb:A0PJL7|uniprotkb:Q8R1H5|ensembl:ENSMUSP00000037441	psi-mi:o53319_myctu(display_long)|uniprotkb:Rv3169(locus name)	psi-mi:atg2b_mouse(display_long)|uniprotkb:Atg2b(gene name)|psi-mi:Atg2b(display_short)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2018)	doi:10.1093/nar/gkx1173|imex:IM-28235|pubmed:29165646	taxid:83332(myctu)|taxid:83332("Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)")	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0471"(MINT)	intact:EBI-25767941|imex:IM-28235-125	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	go:"GO:0005886"(plasma membrane)|mint:O53319|refseq:NP_217685.1|refseq:WP_003416605.1	refseq:NP_083930.5|ensembl:ENSMUSG00000041341(gene)|ensembl:ENSMUST00000041055(transcript)|go:"GO:0000045"(autophagosome assembly)|go:"GO:0000407"(phagophore assembly site)|go:"GO:0000422"(autophagy of mitochondrion)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005811"(lipid droplet)|go:"GO:0019898"(extrinsic component of membrane)|go:"GO:0032266"(phosphatidylinositol-3-phosphate binding)|go:"GO:0034045"(phagophore assembly site membrane)|go:"GO:0034727"(piecemeal microautophagy of the nucleus)|go:"GO:0044805"(late nucleophagy)|go:"GO:0061709"(reticulophagy)|go:"GO:0120013"(lipid transfer activity)|interpro:IPR015412(ATG2, C-terminal)|interpro:IPR026849|interpro:IPR026854|mint:Q80XK6	-	-	-	figure legend:ST5|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2020/07/08	2020/08/14	rogid:Gd1O5B5qTAQflXzn9MR+6fgqvDs83332	rogid:jnUVUCip0mX6qajisFBvpNEqixE10090	rigid:/3luyq07BpGyy0Jlra9p4wcBRzs	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:O07177	uniprotkb:Q80XK6	intact:EBI-25767633|uniprotkb:L0T5L4	intact:EBI-11566520|uniprotkb:Q9CWK6|uniprotkb:Q8BIV0|uniprotkb:Q8BIQ4|uniprotkb:A0PJL7|uniprotkb:Q8R1H5|ensembl:ENSMUSP00000037441	psi-mi:mak1_myctu(display_long)|uniprotkb:mak(gene name)|psi-mi:mak(display_short)|uniprotkb:Maltose-1-phosphate synthase(gene name synonym)|uniprotkb:Rv0127(locus name)	psi-mi:atg2b_mouse(display_long)|uniprotkb:Atg2b(gene name)|psi-mi:Atg2b(display_short)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2018)	doi:10.1093/nar/gkx1173|imex:IM-28235|pubmed:29165646	taxid:83332(myctu)|taxid:83332("Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)")	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0471"(MINT)	intact:EBI-25767947|imex:IM-28235-11	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	go:"GO:0005978"(glycogen biosynthetic process)|go:"GO:0005992"(trehalose biosynthetic process)|go:"GO:0016301"(kinase activity)|go:"GO:0046835"(carbohydrate phosphorylation)|rcsb pdb:4O7O|rcsb pdb:4O7P|go:"GO:0005524"(ATP binding)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|mint:O07177|refseq:NP_214641.1|refseq:WP_003916610.1|interpro:IPR011009(Protein kinase-like)|interpro:IPR040999	refseq:NP_083930.5|ensembl:ENSMUSG00000041341(gene)|ensembl:ENSMUST00000041055(transcript)|go:"GO:0000045"(autophagosome assembly)|go:"GO:0000407"(phagophore assembly site)|go:"GO:0000422"(autophagy of mitochondrion)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005811"(lipid droplet)|go:"GO:0019898"(extrinsic component of membrane)|go:"GO:0032266"(phosphatidylinositol-3-phosphate binding)|go:"GO:0034045"(phagophore assembly site membrane)|go:"GO:0034727"(piecemeal microautophagy of the nucleus)|go:"GO:0044805"(late nucleophagy)|go:"GO:0061709"(reticulophagy)|go:"GO:0120013"(lipid transfer activity)|interpro:IPR015412(ATG2, C-terminal)|interpro:IPR026849|interpro:IPR026854|mint:Q80XK6	-	-	-	figure legend:ST5|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2020/07/08	2020/08/14	rogid:kpl6jZ4UbJUq/kfAlHBYpJAJV4E83332	rogid:jnUVUCip0mX6qajisFBvpNEqixE10090	rigid:GYvhKqYAI6lJcxTJMK6LF9AHP9c	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P9WIT1	uniprotkb:Q80XK6	intact:EBI-25767539|uniprotkb:L0TBU2|uniprotkb:Q50685|uniprotkb:Q7D7C5	intact:EBI-11566520|uniprotkb:Q9CWK6|uniprotkb:Q8BIV0|uniprotkb:Q8BIQ4|uniprotkb:A0PJL7|uniprotkb:Q8R1H5|ensembl:ENSMUSP00000037441	psi-mi:y2280_myctu(display_long)|uniprotkb:Rv2280(locus name)	psi-mi:atg2b_mouse(display_long)|uniprotkb:Atg2b(gene name)|psi-mi:Atg2b(display_short)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2018)	doi:10.1093/nar/gkx1173|imex:IM-28235|pubmed:29165646	taxid:83332(myctu)|taxid:83332("Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)")	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0471"(MINT)	intact:EBI-25767953|imex:IM-28235-227	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	go:"GO:0005618"(cell wall)|go:"GO:0005886"(plasma membrane)|go:"GO:0016491"(oxidoreductase activity)|go:"GO:0071949"(FAD binding)|interpro:IPR016169(CO dehydrogenase flavoprotein-like, FAD-binding, subdomain 2)|mint:P9WIT1|refseq:WP_003411690.1|interpro:IPR016166(FAD-binding, type 2)|interpro:IPR036318|interpro:IPR016164(FAD-linked oxidase-like, C-terminal)|interpro:IPR004113(FAD-linked oxidase, C-terminal)|interpro:IPR006094(FAD linked oxidase, N-terminal)|interpro:IPR016171(Vanillyl-alcohol oxidase, C-terminal subdomain 2)	refseq:NP_083930.5|ensembl:ENSMUSG00000041341(gene)|ensembl:ENSMUST00000041055(transcript)|go:"GO:0000045"(autophagosome assembly)|go:"GO:0000407"(phagophore assembly site)|go:"GO:0000422"(autophagy of mitochondrion)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005811"(lipid droplet)|go:"GO:0019898"(extrinsic component of membrane)|go:"GO:0032266"(phosphatidylinositol-3-phosphate binding)|go:"GO:0034045"(phagophore assembly site membrane)|go:"GO:0034727"(piecemeal microautophagy of the nucleus)|go:"GO:0044805"(late nucleophagy)|go:"GO:0061709"(reticulophagy)|go:"GO:0120013"(lipid transfer activity)|interpro:IPR015412(ATG2, C-terminal)|interpro:IPR026849|interpro:IPR026854|mint:Q80XK6	-	-	-	figure legend:ST5|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2020/07/08	2020/08/14	rogid:TvFI3uuw9zREl1q0DeWIsHmCSEk83332	rogid:jnUVUCip0mX6qajisFBvpNEqixE10090	rigid:6DxKMnlnJQdwnQVEOEG2P5j8Q5c	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:I6Y946	uniprotkb:Q80XK6	intact:EBI-25767727	intact:EBI-11566520|uniprotkb:Q9CWK6|uniprotkb:Q8BIV0|uniprotkb:Q8BIQ4|uniprotkb:A0PJL7|uniprotkb:Q8R1H5|ensembl:ENSMUSP00000037441	psi-mi:i6y946_myctu(display_long)|uniprotkb:Rv0925c(locus name)	psi-mi:atg2b_mouse(display_long)|uniprotkb:Atg2b(gene name)|psi-mi:Atg2b(display_short)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2018)	doi:10.1093/nar/gkx1173|imex:IM-28235|pubmed:29165646	taxid:83332(myctu)|taxid:83332("Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)")	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0471"(MINT)	intact:EBI-25767965|imex:IM-28235-127	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	go:"GO:0016491"(oxidoreductase activity)|mint:I6Y946|refseq:NP_215440.1|refseq:WP_003404764.1|interpro:IPR029039|interpro:IPR005025(NADPH-dependent FMN reductase)	refseq:NP_083930.5|ensembl:ENSMUSG00000041341(gene)|ensembl:ENSMUST00000041055(transcript)|go:"GO:0000045"(autophagosome assembly)|go:"GO:0000407"(phagophore assembly site)|go:"GO:0000422"(autophagy of mitochondrion)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005811"(lipid droplet)|go:"GO:0019898"(extrinsic component of membrane)|go:"GO:0032266"(phosphatidylinositol-3-phosphate binding)|go:"GO:0034045"(phagophore assembly site membrane)|go:"GO:0034727"(piecemeal microautophagy of the nucleus)|go:"GO:0044805"(late nucleophagy)|go:"GO:0061709"(reticulophagy)|go:"GO:0120013"(lipid transfer activity)|interpro:IPR015412(ATG2, C-terminal)|interpro:IPR026849|interpro:IPR026854|mint:Q80XK6	-	-	-	figure legend:ST5|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2020/07/08	2020/08/14	rogid:JOW06LtizimdrjJdMmMnM9ru8n083332	rogid:jnUVUCip0mX6qajisFBvpNEqixE10090	rigid:FljHBpawKUDeH/W4Ags3VGWjQn8	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:O53319	uniprotkb:Q80XK6	intact:EBI-25767766|uniprotkb:I6X6K2|uniprotkb:L0TEH7	intact:EBI-11566520|uniprotkb:Q9CWK6|uniprotkb:Q8BIV0|uniprotkb:Q8BIQ4|uniprotkb:A0PJL7|uniprotkb:Q8R1H5|ensembl:ENSMUSP00000037441	psi-mi:o53319_myctu(display_long)|uniprotkb:Rv3169(locus name)	psi-mi:atg2b_mouse(display_long)|uniprotkb:Atg2b(gene name)|psi-mi:Atg2b(display_short)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2018)	doi:10.1093/nar/gkx1173|imex:IM-28235|pubmed:29165646	taxid:83332(myctu)|taxid:83332("Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)")	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0471"(MINT)	intact:EBI-25767971|imex:IM-28235-231	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	go:"GO:0005886"(plasma membrane)|mint:O53319|refseq:NP_217685.1|refseq:WP_003416605.1	refseq:NP_083930.5|ensembl:ENSMUSG00000041341(gene)|ensembl:ENSMUST00000041055(transcript)|go:"GO:0000045"(autophagosome assembly)|go:"GO:0000407"(phagophore assembly site)|go:"GO:0000422"(autophagy of mitochondrion)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005811"(lipid droplet)|go:"GO:0019898"(extrinsic component of membrane)|go:"GO:0032266"(phosphatidylinositol-3-phosphate binding)|go:"GO:0034045"(phagophore assembly site membrane)|go:"GO:0034727"(piecemeal microautophagy of the nucleus)|go:"GO:0044805"(late nucleophagy)|go:"GO:0061709"(reticulophagy)|go:"GO:0120013"(lipid transfer activity)|interpro:IPR015412(ATG2, C-terminal)|interpro:IPR026849|interpro:IPR026854|mint:Q80XK6	-	-	-	figure legend:ST5|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2020/07/08	2020/08/14	rogid:Gd1O5B5qTAQflXzn9MR+6fgqvDs83332	rogid:jnUVUCip0mX6qajisFBvpNEqixE10090	rigid:/3luyq07BpGyy0Jlra9p4wcBRzs	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q8R4K2	uniprotkb:P9WIT1	intact:EBI-3842721|uniprotkb:Q80WW1|ensembl:ENSMUSP00000074471	intact:EBI-25767539|uniprotkb:L0TBU2|uniprotkb:Q50685|uniprotkb:Q7D7C5	psi-mi:irak4_mouse(display_long)|uniprotkb:Irak4(gene name)|psi-mi:Irak4(display_short)	psi-mi:y2280_myctu(display_long)|uniprotkb:Rv2280(locus name)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2018)	doi:10.1093/nar/gkx1173|imex:IM-28235|pubmed:29165646	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:83332(myctu)|taxid:83332("Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)")	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0471"(MINT)	intact:EBI-25767977|imex:IM-28235-51	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_084202.2|dip:DIP-48996N|ensembl:ENSMUSG00000059883(gene)|ensembl:ENSMUST00000074936(transcript)|go:"GO:0000287"(magnesium ion binding)|go:"GO:0002446"(neutrophil mediated immunity)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0005149"(interleukin-1 receptor binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0007254"(JNK cascade)|go:"GO:0019221"(cytokine-mediated signaling pathway)|go:"GO:0019901"(protein kinase binding)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0045087"(innate immune response)|go:"GO:0048661"(positive regulation of smooth muscle cell proliferation)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:1990266"(neutrophil migration)|interpro:IPR000719(Protein kinase, core)|interpro:IPR011009(Protein kinase-like)|interpro:IPR011029(DEATH-like)|interpro:IPR017428(Interleukin-1 receptor-associated kinase 4)|interpro:IPR037970|mint:Q8R4K2|rcsb pdb:1WH4|rcsb pdb:2A9I|reactome:R-MMU-1257604|reactome:R-MMU-6811558|reactome:R-MMU-9020702	go:"GO:0005618"(cell wall)|go:"GO:0005886"(plasma membrane)|go:"GO:0016491"(oxidoreductase activity)|go:"GO:0071949"(FAD binding)|interpro:IPR016169(CO dehydrogenase flavoprotein-like, FAD-binding, subdomain 2)|mint:P9WIT1|refseq:WP_003411690.1|interpro:IPR016166(FAD-binding, type 2)|interpro:IPR036318|interpro:IPR016164(FAD-linked oxidase-like, C-terminal)|interpro:IPR004113(FAD-linked oxidase, C-terminal)|interpro:IPR006094(FAD linked oxidase, N-terminal)|interpro:IPR016171(Vanillyl-alcohol oxidase, C-terminal subdomain 2)	-	-	-	figure legend:ST5|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2020/07/08	2020/08/14	rogid:wreOQx/3vm3HfDiUt8mriWGR6Lc10090	rogid:TvFI3uuw9zREl1q0DeWIsHmCSEk83332	rigid:rOUx2FgXNvSjWBJtOcYCJ8o+Ub0	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q8R4K2	uniprotkb:I6Y946	intact:EBI-3842721|uniprotkb:Q80WW1|ensembl:ENSMUSP00000074471	intact:EBI-25767727	psi-mi:irak4_mouse(display_long)|uniprotkb:Irak4(gene name)|psi-mi:Irak4(display_short)	psi-mi:i6y946_myctu(display_long)|uniprotkb:Rv0925c(locus name)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2018)	doi:10.1093/nar/gkx1173|imex:IM-28235|pubmed:29165646	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:83332(myctu)|taxid:83332("Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)")	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0471"(MINT)	intact:EBI-25767983|imex:IM-28235-129	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_084202.2|dip:DIP-48996N|ensembl:ENSMUSG00000059883(gene)|ensembl:ENSMUST00000074936(transcript)|go:"GO:0000287"(magnesium ion binding)|go:"GO:0002446"(neutrophil mediated immunity)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0005149"(interleukin-1 receptor binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0007254"(JNK cascade)|go:"GO:0019221"(cytokine-mediated signaling pathway)|go:"GO:0019901"(protein kinase binding)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0045087"(innate immune response)|go:"GO:0048661"(positive regulation of smooth muscle cell proliferation)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:1990266"(neutrophil migration)|interpro:IPR000719(Protein kinase, core)|interpro:IPR011009(Protein kinase-like)|interpro:IPR011029(DEATH-like)|interpro:IPR017428(Interleukin-1 receptor-associated kinase 4)|interpro:IPR037970|mint:Q8R4K2|rcsb pdb:1WH4|rcsb pdb:2A9I|reactome:R-MMU-1257604|reactome:R-MMU-6811558|reactome:R-MMU-9020702	go:"GO:0016491"(oxidoreductase activity)|mint:I6Y946|refseq:NP_215440.1|refseq:WP_003404764.1|interpro:IPR029039|interpro:IPR005025(NADPH-dependent FMN reductase)	-	-	-	figure legend:ST5|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2020/07/08	2020/08/14	rogid:wreOQx/3vm3HfDiUt8mriWGR6Lc10090	rogid:JOW06LtizimdrjJdMmMnM9ru8n083332	rigid:g3lahA/1PiQCNnVlPTEPEtvOsI4	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:O69689	uniprotkb:Q8K4B2	intact:EBI-25767781|uniprotkb:F2GFU4|uniprotkb:I6Y4D4|uniprotkb:Q7D501	intact:EBI-646179|uniprotkb:Q8C7U8|uniprotkb:Q8CE40|uniprotkb:Q8K1S8|ensembl:ENSMUSP00000020448	psi-mi:aspat_myctu(display_long)|uniprotkb:Rv3722c(locus name)	psi-mi:irak3_mouse(display_long)|uniprotkb:IL-1 receptor-associated kinase M(gene name synonym)|uniprotkb:Irak3(gene name)|psi-mi:Irak3(display_short)|uniprotkb:Inactive IL-1 receptor-associated kinase 3(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2018)	doi:10.1093/nar/gkx1173|imex:IM-28235|pubmed:29165646	taxid:83332(myctu)|taxid:83332("Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)")	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0471"(MINT)	intact:EBI-25767989|imex:IM-28235-309	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	go:"GO:0004069"("L-aspartate:2-oxoglutarate aminotransferase activity")|go:"GO:0005576"(extracellular region)|rcsb pdb:5C6U|rcsb pdb:6U78|rcsb pdb:6U7A|mint:O69689|refseq:NP_218239.2|refseq:WP_003899653.1|interpro:IPR024551|interpro:IPR015424(Pyridoxal phosphate-dependent transferase, major region)|interpro:IPR015422(Pyridoxal phosphate-dependent transferase, major region, subdomain 2)|interpro:IPR015421(Pyridoxal phosphate-dependent transferase, major region, subdomain 1)	refseq:NP_082955.2|go:"GO:0001960"(negative regulation of cytokine-mediated signaling pathway)|go:"GO:0002755"(MyD88-dependent toll-like receptor signaling pathway)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0009615"(response to virus)|go:"GO:0010933"(positive regulation of macrophage tolerance induction)|go:"GO:0010936"(negative regulation of macrophage cytokine production)|go:"GO:0019221"(cytokine-mediated signaling pathway)|go:"GO:0019901"(protein kinase binding)|go:"GO:0032088"(negative regulation of NF-kappaB transcription factor activity)|go:"GO:0032494"(response to peptidoglycan)|go:"GO:0032496"(response to lipopolysaccharide)|go:"GO:0032695"(negative regulation of interleukin-12 production)|go:"GO:0032715"(negative regulation of interleukin-6 production)|go:"GO:0032720"(negative regulation of tumor necrosis factor production)|go:"GO:0034122"(negative regulation of toll-like receptor signaling pathway)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0042177"(negative regulation of protein catabolic process)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043242"(negative regulation of protein-containing complex disassembly)|go:"GO:0043244"(regulation of protein-containing complex disassembly)|go:"GO:0043330"(response to exogenous dsRNA)|go:"GO:0043407"(negative regulation of MAP kinase activity)|go:"GO:0045824"(negative regulation of innate immune response)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|go:"GO:0070498"(interleukin-1-mediated signaling pathway)|go:"GO:0070555"(response to interleukin-1)|interpro:IPR000488(Death)|interpro:IPR000719(Protein kinase, core)|interpro:IPR011009(Protein kinase-like)|interpro:IPR011029(DEATH-like)|interpro:IPR033610|interpro:IPR042698|interpro:IPR042747|mint:Q8K4B2|reactome:R-MMU-9020702|ensembl:ENSMUSG00000020227(gene)|ensembl:ENSMUST00000020448(transcript)|go:"GO:0000287"(magnesium ion binding)|go:"GO:0001819"(positive regulation of cytokine production)	-	-	-	figure legend:ST5|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2020/07/08	2020/08/14	rogid:TGWnUCrIwLrRrMnna5+/w33GpgA83332	rogid:oIjgqYFjr3oyFSGixSb2jrq03Cc10090	rigid:gCLcubx0RMdC7O//T59HiYMMsC8	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P71619	uniprotkb:Q8K4B2	intact:EBI-25767582|uniprotkb:F2GLA0|uniprotkb:I6YAD4	intact:EBI-646179|uniprotkb:Q8C7U8|uniprotkb:Q8CE40|uniprotkb:Q8K1S8|ensembl:ENSMUSP00000020448	psi-mi:p71619_myctu(display_long)|uniprotkb:ugpB(gene name)|psi-mi:ugpB(display_short)|uniprotkb:Rv2833c(locus name)	psi-mi:irak3_mouse(display_long)|uniprotkb:IL-1 receptor-associated kinase M(gene name synonym)|uniprotkb:Irak3(gene name)|psi-mi:Irak3(display_short)|uniprotkb:Inactive IL-1 receptor-associated kinase 3(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2018)	doi:10.1093/nar/gkx1173|imex:IM-28235|pubmed:29165646	taxid:83332(myctu)|taxid:83332("Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)")	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0471"(MINT)	intact:EBI-25767995|imex:IM-28235-233	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	go:"GO:0005886"(plasma membrane)|rcsb pdb:6R1B|mint:P71619|refseq:NP_217349.1|refseq:WP_003414501.1|interpro:IPR006059(Bacterial extracellular solute-binding, family 1)|interpro:IPR006311(Twin-arginine translocation pathway signal)	refseq:NP_082955.2|go:"GO:0001960"(negative regulation of cytokine-mediated signaling pathway)|go:"GO:0002755"(MyD88-dependent toll-like receptor signaling pathway)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0009615"(response to virus)|go:"GO:0010933"(positive regulation of macrophage tolerance induction)|go:"GO:0010936"(negative regulation of macrophage cytokine production)|go:"GO:0019221"(cytokine-mediated signaling pathway)|go:"GO:0019901"(protein kinase binding)|go:"GO:0032088"(negative regulation of NF-kappaB transcription factor activity)|go:"GO:0032494"(response to peptidoglycan)|go:"GO:0032496"(response to lipopolysaccharide)|go:"GO:0032695"(negative regulation of interleukin-12 production)|go:"GO:0032715"(negative regulation of interleukin-6 production)|go:"GO:0032720"(negative regulation of tumor necrosis factor production)|go:"GO:0034122"(negative regulation of toll-like receptor signaling pathway)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0042177"(negative regulation of protein catabolic process)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043242"(negative regulation of protein-containing complex disassembly)|go:"GO:0043244"(regulation of protein-containing complex disassembly)|go:"GO:0043330"(response to exogenous dsRNA)|go:"GO:0043407"(negative regulation of MAP kinase activity)|go:"GO:0045824"(negative regulation of innate immune response)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|go:"GO:0070498"(interleukin-1-mediated signaling pathway)|go:"GO:0070555"(response to interleukin-1)|interpro:IPR000488(Death)|interpro:IPR000719(Protein kinase, core)|interpro:IPR011009(Protein kinase-like)|interpro:IPR011029(DEATH-like)|interpro:IPR033610|interpro:IPR042698|interpro:IPR042747|mint:Q8K4B2|reactome:R-MMU-9020702|ensembl:ENSMUSG00000020227(gene)|ensembl:ENSMUST00000020448(transcript)|go:"GO:0000287"(magnesium ion binding)|go:"GO:0001819"(positive regulation of cytokine production)	-	-	-	figure legend:ST5|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2020/07/08	2020/08/14	rogid:ldo4FA/3ddzSo1mfnNEPte27F1083332	rogid:oIjgqYFjr3oyFSGixSb2jrq03Cc10090	rigid:wKloWGRySDk9njm1jlssZfMHEv4	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P9WN37	uniprotkb:Q8K4B2	intact:EBI-25767601|uniprotkb:L0T968|uniprotkb:P64245|uniprotkb:Q10378	intact:EBI-646179|uniprotkb:Q8C7U8|uniprotkb:Q8CE40|uniprotkb:Q8K1S8|ensembl:ENSMUSP00000020448	psi-mi:gln1a_myctu(display_long)|uniprotkb:glnA2(gene name)|psi-mi:glnA2(display_short)|uniprotkb:Glutamate--ammonia ligase(gene name synonym)|uniprotkb:Glutamine synthetase I alpha(gene name synonym)|uniprotkb:MTCY190.33c(orf name)|uniprotkb:MTCY427.03c(orf name)|uniprotkb:Rv2222c(locus name)	psi-mi:irak3_mouse(display_long)|uniprotkb:IL-1 receptor-associated kinase M(gene name synonym)|uniprotkb:Irak3(gene name)|psi-mi:Irak3(display_short)|uniprotkb:Inactive IL-1 receptor-associated kinase 3(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2018)	doi:10.1093/nar/gkx1173|imex:IM-28235|pubmed:29165646	taxid:83332(myctu)|taxid:83332("Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)")	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0471"(MINT)	intact:EBI-25768001|imex:IM-28235-311	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	go:"GO:0004356"(glutamate-ammonia ligase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0006542"(glutamine biosynthetic process)|go:"GO:0046872"(metal ion binding)|go:"GO:0050001"(D-glutaminase activity)|mint:P9WN37|refseq:NP_216738.1|refseq:WP_003411482.1|interpro:IPR008147(Glutamine synthetase, beta-Grasp)|interpro:IPR036651|interpro:IPR014746(Glutamine synthetase/guanido kinase, catalytic region)|interpro:IPR008146(Glutamine synthetase, catalytic region)|interpro:IPR027303	refseq:NP_082955.2|go:"GO:0001960"(negative regulation of cytokine-mediated signaling pathway)|go:"GO:0002755"(MyD88-dependent toll-like receptor signaling pathway)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0009615"(response to virus)|go:"GO:0010933"(positive regulation of macrophage tolerance induction)|go:"GO:0010936"(negative regulation of macrophage cytokine production)|go:"GO:0019221"(cytokine-mediated signaling pathway)|go:"GO:0019901"(protein kinase binding)|go:"GO:0032088"(negative regulation of NF-kappaB transcription factor activity)|go:"GO:0032494"(response to peptidoglycan)|go:"GO:0032496"(response to lipopolysaccharide)|go:"GO:0032695"(negative regulation of interleukin-12 production)|go:"GO:0032715"(negative regulation of interleukin-6 production)|go:"GO:0032720"(negative regulation of tumor necrosis factor production)|go:"GO:0034122"(negative regulation of toll-like receptor signaling pathway)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0042177"(negative regulation of protein catabolic process)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043242"(negative regulation of protein-containing complex disassembly)|go:"GO:0043244"(regulation of protein-containing complex disassembly)|go:"GO:0043330"(response to exogenous dsRNA)|go:"GO:0043407"(negative regulation of MAP kinase activity)|go:"GO:0045824"(negative regulation of innate immune response)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|go:"GO:0070498"(interleukin-1-mediated signaling pathway)|go:"GO:0070555"(response to interleukin-1)|interpro:IPR000488(Death)|interpro:IPR000719(Protein kinase, core)|interpro:IPR011009(Protein kinase-like)|interpro:IPR011029(DEATH-like)|interpro:IPR033610|interpro:IPR042698|interpro:IPR042747|mint:Q8K4B2|reactome:R-MMU-9020702|ensembl:ENSMUSG00000020227(gene)|ensembl:ENSMUST00000020448(transcript)|go:"GO:0000287"(magnesium ion binding)|go:"GO:0001819"(positive regulation of cytokine production)	-	-	-	figure legend:ST5|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2020/07/08	2020/08/14	rogid:LDIpolmw5yhv2iG5+8HKbWlwT8883332	rogid:oIjgqYFjr3oyFSGixSb2jrq03Cc10090	rigid:pYoK5SFWwkGKP+97FLgywd6HKcU	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:L7N684	uniprotkb:Q8K4B2	intact:EBI-25768007|uniprotkb:I6XZY1	intact:EBI-646179|uniprotkb:Q8C7U8|uniprotkb:Q8CE40|uniprotkb:Q8K1S8|ensembl:ENSMUSP00000020448	psi-mi:l7n684_myctu(display_long)|uniprotkb:Rv2141c(locus name)	psi-mi:irak3_mouse(display_long)|uniprotkb:IL-1 receptor-associated kinase M(gene name synonym)|uniprotkb:Irak3(gene name)|psi-mi:Irak3(display_short)|uniprotkb:Inactive IL-1 receptor-associated kinase 3(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2018)	doi:10.1093/nar/gkx1173|imex:IM-28235|pubmed:29165646	taxid:83332(myctu)|taxid:83332("Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)")	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0471"(MINT)	intact:EBI-25768022|imex:IM-28235-131	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	go:"GO:0006526"(arginine biosynthetic process)|go:"GO:0008777"(acetylornithine deacetylase activity)|mint:L7N684|refseq:WP_003411121.1|refseq:YP_177864.1|interpro:IPR001261(ArgE/DapE/ACY1/CPG2/YscS, conserved site)|interpro:IPR036264|interpro:IPR002933(Peptidase M20)|interpro:IPR011650(Peptidase M20, dimerisation)	refseq:NP_082955.2|go:"GO:0001960"(negative regulation of cytokine-mediated signaling pathway)|go:"GO:0002755"(MyD88-dependent toll-like receptor signaling pathway)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0009615"(response to virus)|go:"GO:0010933"(positive regulation of macrophage tolerance induction)|go:"GO:0010936"(negative regulation of macrophage cytokine production)|go:"GO:0019221"(cytokine-mediated signaling pathway)|go:"GO:0019901"(protein kinase binding)|go:"GO:0032088"(negative regulation of NF-kappaB transcription factor activity)|go:"GO:0032494"(response to peptidoglycan)|go:"GO:0032496"(response to lipopolysaccharide)|go:"GO:0032695"(negative regulation of interleukin-12 production)|go:"GO:0032715"(negative regulation of interleukin-6 production)|go:"GO:0032720"(negative regulation of tumor necrosis factor production)|go:"GO:0034122"(negative regulation of toll-like receptor signaling pathway)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0042177"(negative regulation of protein catabolic process)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043242"(negative regulation of protein-containing complex disassembly)|go:"GO:0043244"(regulation of protein-containing complex disassembly)|go:"GO:0043330"(response to exogenous dsRNA)|go:"GO:0043407"(negative regulation of MAP kinase activity)|go:"GO:0045824"(negative regulation of innate immune response)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|go:"GO:0070498"(interleukin-1-mediated signaling pathway)|go:"GO:0070555"(response to interleukin-1)|interpro:IPR000488(Death)|interpro:IPR000719(Protein kinase, core)|interpro:IPR011009(Protein kinase-like)|interpro:IPR011029(DEATH-like)|interpro:IPR033610|interpro:IPR042698|interpro:IPR042747|mint:Q8K4B2|reactome:R-MMU-9020702|ensembl:ENSMUSG00000020227(gene)|ensembl:ENSMUST00000020448(transcript)|go:"GO:0000287"(magnesium ion binding)|go:"GO:0001819"(positive regulation of cytokine production)	-	-	-	figure legend:ST5|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2020/07/08	2020/08/14	rogid:c/gr5TMeB+nx0CZHLBZI7YeVioo83332	rogid:oIjgqYFjr3oyFSGixSb2jrq03Cc10090	rigid:IlzvSrNgAy8/nuYgOPOANvlXUIw	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:O07177	uniprotkb:Q8K4B2	intact:EBI-25767633|uniprotkb:L0T5L4	intact:EBI-646179|uniprotkb:Q8C7U8|uniprotkb:Q8CE40|uniprotkb:Q8K1S8|ensembl:ENSMUSP00000020448	psi-mi:mak1_myctu(display_long)|uniprotkb:mak(gene name)|psi-mi:mak(display_short)|uniprotkb:Maltose-1-phosphate synthase(gene name synonym)|uniprotkb:Rv0127(locus name)	psi-mi:irak3_mouse(display_long)|uniprotkb:IL-1 receptor-associated kinase M(gene name synonym)|uniprotkb:Irak3(gene name)|psi-mi:Irak3(display_short)|uniprotkb:Inactive IL-1 receptor-associated kinase 3(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2018)	doi:10.1093/nar/gkx1173|imex:IM-28235|pubmed:29165646	taxid:83332(myctu)|taxid:83332("Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)")	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0471"(MINT)	intact:EBI-25768028|imex:IM-28235-13	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	go:"GO:0005978"(glycogen biosynthetic process)|go:"GO:0005992"(trehalose biosynthetic process)|go:"GO:0016301"(kinase activity)|go:"GO:0046835"(carbohydrate phosphorylation)|rcsb pdb:4O7O|rcsb pdb:4O7P|go:"GO:0005524"(ATP binding)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|mint:O07177|refseq:NP_214641.1|refseq:WP_003916610.1|interpro:IPR011009(Protein kinase-like)|interpro:IPR040999	refseq:NP_082955.2|go:"GO:0001960"(negative regulation of cytokine-mediated signaling pathway)|go:"GO:0002755"(MyD88-dependent toll-like receptor signaling pathway)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0009615"(response to virus)|go:"GO:0010933"(positive regulation of macrophage tolerance induction)|go:"GO:0010936"(negative regulation of macrophage cytokine production)|go:"GO:0019221"(cytokine-mediated signaling pathway)|go:"GO:0019901"(protein kinase binding)|go:"GO:0032088"(negative regulation of NF-kappaB transcription factor activity)|go:"GO:0032494"(response to peptidoglycan)|go:"GO:0032496"(response to lipopolysaccharide)|go:"GO:0032695"(negative regulation of interleukin-12 production)|go:"GO:0032715"(negative regulation of interleukin-6 production)|go:"GO:0032720"(negative regulation of tumor necrosis factor production)|go:"GO:0034122"(negative regulation of toll-like receptor signaling pathway)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0042177"(negative regulation of protein catabolic process)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043242"(negative regulation of protein-containing complex disassembly)|go:"GO:0043244"(regulation of protein-containing complex disassembly)|go:"GO:0043330"(response to exogenous dsRNA)|go:"GO:0043407"(negative regulation of MAP kinase activity)|go:"GO:0045824"(negative regulation of innate immune response)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|go:"GO:0070498"(interleukin-1-mediated signaling pathway)|go:"GO:0070555"(response to interleukin-1)|interpro:IPR000488(Death)|interpro:IPR000719(Protein kinase, core)|interpro:IPR011009(Protein kinase-like)|interpro:IPR011029(DEATH-like)|interpro:IPR033610|interpro:IPR042698|interpro:IPR042747|mint:Q8K4B2|reactome:R-MMU-9020702|ensembl:ENSMUSG00000020227(gene)|ensembl:ENSMUST00000020448(transcript)|go:"GO:0000287"(magnesium ion binding)|go:"GO:0001819"(positive regulation of cytokine production)	-	-	-	figure legend:ST5|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2020/07/08	2020/08/14	rogid:kpl6jZ4UbJUq/kfAlHBYpJAJV4E83332	rogid:oIjgqYFjr3oyFSGixSb2jrq03Cc10090	rigid:VTAaUjHts/nadRyR3ZvkKJQWw2Q	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q8K4B2	uniprotkb:P9WNI7	intact:EBI-646179|uniprotkb:Q8C7U8|uniprotkb:Q8CE40|uniprotkb:Q8K1S8|ensembl:ENSMUSP00000020448	intact:EBI-9027314|uniprotkb:P95242|uniprotkb:L0T9C9	psi-mi:irak3_mouse(display_long)|uniprotkb:IL-1 receptor-associated kinase M(gene name synonym)|uniprotkb:Irak3(gene name)|psi-mi:Irak3(display_short)|uniprotkb:Inactive IL-1 receptor-associated kinase 3(gene name synonym)	psi-mi:esxo_myctu(display_long)|uniprotkb:esxO(gene name)|psi-mi:esxO(display_short)|uniprotkb:MTCY98.15c(orf name)|uniprotkb:Rv2346c(locus name)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2018)	doi:10.1093/nar/gkx1173|imex:IM-28235|pubmed:29165646	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:83332(myctu)|taxid:83332("Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)")	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0471"(MINT)	intact:EBI-25768040|imex:IM-28235-133	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_082955.2|go:"GO:0001960"(negative regulation of cytokine-mediated signaling pathway)|go:"GO:0002755"(MyD88-dependent toll-like receptor signaling pathway)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0009615"(response to virus)|go:"GO:0010933"(positive regulation of macrophage tolerance induction)|go:"GO:0010936"(negative regulation of macrophage cytokine production)|go:"GO:0019221"(cytokine-mediated signaling pathway)|go:"GO:0019901"(protein kinase binding)|go:"GO:0032088"(negative regulation of NF-kappaB transcription factor activity)|go:"GO:0032494"(response to peptidoglycan)|go:"GO:0032496"(response to lipopolysaccharide)|go:"GO:0032695"(negative regulation of interleukin-12 production)|go:"GO:0032715"(negative regulation of interleukin-6 production)|go:"GO:0032720"(negative regulation of tumor necrosis factor production)|go:"GO:0034122"(negative regulation of toll-like receptor signaling pathway)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0042177"(negative regulation of protein catabolic process)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043242"(negative regulation of protein-containing complex disassembly)|go:"GO:0043244"(regulation of protein-containing complex disassembly)|go:"GO:0043330"(response to exogenous dsRNA)|go:"GO:0043407"(negative regulation of MAP kinase activity)|go:"GO:0045824"(negative regulation of innate immune response)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|go:"GO:0070498"(interleukin-1-mediated signaling pathway)|go:"GO:0070555"(response to interleukin-1)|interpro:IPR000488(Death)|interpro:IPR000719(Protein kinase, core)|interpro:IPR011009(Protein kinase-like)|interpro:IPR011029(DEATH-like)|interpro:IPR033610|interpro:IPR042698|interpro:IPR042747|mint:Q8K4B2|reactome:R-MMU-9020702|ensembl:ENSMUSG00000020227(gene)|ensembl:ENSMUST00000020448(transcript)|go:"GO:0000287"(magnesium ion binding)|go:"GO:0001819"(positive regulation of cytokine production)	mint:P9WNI7|interpro:IPR036689|interpro:IPR009416(Protein of unknown function DUF1066)|interpro:IPR010310(Protein of unknown function DUF909)|refseq:NP_216862.1|refseq:WP_003899283.1|go:"GO:0005576"(extracellular region)|go:"GO:0005618"(cell wall)|go:"GO:0005886"(plasma membrane)|rcsb pdb:3OGI|rcsb pdb:4GZR	-	-	-	figure legend:ST5|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2020/07/08	2020/08/14	rogid:oIjgqYFjr3oyFSGixSb2jrq03Cc10090	rogid:jYoNmHY+G6+S39CX1qRFCxjy0xw83332	rigid:84zk6w/rNbO2RafioKlP9PhUuVE	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P9WIT1	uniprotkb:Q8K4B2	intact:EBI-25767539|uniprotkb:L0TBU2|uniprotkb:Q50685|uniprotkb:Q7D7C5	intact:EBI-646179|uniprotkb:Q8C7U8|uniprotkb:Q8CE40|uniprotkb:Q8K1S8|ensembl:ENSMUSP00000020448	psi-mi:y2280_myctu(display_long)|uniprotkb:Rv2280(locus name)	psi-mi:irak3_mouse(display_long)|uniprotkb:IL-1 receptor-associated kinase M(gene name synonym)|uniprotkb:Irak3(gene name)|psi-mi:Irak3(display_short)|uniprotkb:Inactive IL-1 receptor-associated kinase 3(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2018)	doi:10.1093/nar/gkx1173|imex:IM-28235|pubmed:29165646	taxid:83332(myctu)|taxid:83332("Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)")	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0471"(MINT)	intact:EBI-25768034|imex:IM-28235-235	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	go:"GO:0005618"(cell wall)|go:"GO:0005886"(plasma membrane)|go:"GO:0016491"(oxidoreductase activity)|go:"GO:0071949"(FAD binding)|interpro:IPR016169(CO dehydrogenase flavoprotein-like, FAD-binding, subdomain 2)|mint:P9WIT1|refseq:WP_003411690.1|interpro:IPR016166(FAD-binding, type 2)|interpro:IPR036318|interpro:IPR016164(FAD-linked oxidase-like, C-terminal)|interpro:IPR004113(FAD-linked oxidase, C-terminal)|interpro:IPR006094(FAD linked oxidase, N-terminal)|interpro:IPR016171(Vanillyl-alcohol oxidase, C-terminal subdomain 2)	refseq:NP_082955.2|go:"GO:0001960"(negative regulation of cytokine-mediated signaling pathway)|go:"GO:0002755"(MyD88-dependent toll-like receptor signaling pathway)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0009615"(response to virus)|go:"GO:0010933"(positive regulation of macrophage tolerance induction)|go:"GO:0010936"(negative regulation of macrophage cytokine production)|go:"GO:0019221"(cytokine-mediated signaling pathway)|go:"GO:0019901"(protein kinase binding)|go:"GO:0032088"(negative regulation of NF-kappaB transcription factor activity)|go:"GO:0032494"(response to peptidoglycan)|go:"GO:0032496"(response to lipopolysaccharide)|go:"GO:0032695"(negative regulation of interleukin-12 production)|go:"GO:0032715"(negative regulation of interleukin-6 production)|go:"GO:0032720"(negative regulation of tumor necrosis factor production)|go:"GO:0034122"(negative regulation of toll-like receptor signaling pathway)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0042177"(negative regulation of protein catabolic process)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043242"(negative regulation of protein-containing complex disassembly)|go:"GO:0043244"(regulation of protein-containing complex disassembly)|go:"GO:0043330"(response to exogenous dsRNA)|go:"GO:0043407"(negative regulation of MAP kinase activity)|go:"GO:0045824"(negative regulation of innate immune response)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|go:"GO:0070498"(interleukin-1-mediated signaling pathway)|go:"GO:0070555"(response to interleukin-1)|interpro:IPR000488(Death)|interpro:IPR000719(Protein kinase, core)|interpro:IPR011009(Protein kinase-like)|interpro:IPR011029(DEATH-like)|interpro:IPR033610|interpro:IPR042698|interpro:IPR042747|mint:Q8K4B2|reactome:R-MMU-9020702|ensembl:ENSMUSG00000020227(gene)|ensembl:ENSMUST00000020448(transcript)|go:"GO:0000287"(magnesium ion binding)|go:"GO:0001819"(positive regulation of cytokine production)	-	-	-	figure legend:ST5|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2020/07/08	2020/08/14	rogid:TvFI3uuw9zREl1q0DeWIsHmCSEk83332	rogid:oIjgqYFjr3oyFSGixSb2jrq03Cc10090	rigid:keoALv1qCF9PlDUg64VP017x2wc	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P9WJB9	uniprotkb:Q80U62	intact:EBI-25767670|uniprotkb:L0TE21|uniprotkb:O69744|uniprotkb:Q7D4P0	intact:EBI-3506572|uniprotkb:Q3TAX3|uniprotkb:Q3TD96|uniprotkb:Q3TDF7|uniprotkb:Q3TDU2|uniprotkb:Q6NWW8|uniprotkb:Q6P9T7|uniprotkb:Q6PG18|uniprotkb:Q8BMP7|uniprotkb:Q8BY22|ensembl:ENSMUSP00000087114	psi-mi:espl_myctu(display_long)|uniprotkb:espL(gene name)|psi-mi:espL(display_short)|uniprotkb:Rv3880c(locus name)	psi-mi:rubic_mouse(display_long)|uniprotkb:Rubcn(gene name)|psi-mi:Rubcn(display_short)|uniprotkb:Kiaa0226(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2018)	doi:10.1093/nar/gkx1173|imex:IM-28235|pubmed:29165646	taxid:83332(myctu)|taxid:83332("Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)")	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0471"(MINT)	intact:EBI-25768382|imex:IM-28235-149	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	go:"GO:0003677"(DNA binding)|go:"GO:0005618"(cell wall)|go:"GO:0005886"(plasma membrane)|go:"GO:0052170"(suppression by symbiont of host innate immune response)|mint:P9WJB9|refseq:NP_218397.1|refseq:WP_003399988.1|interpro:IPR036894|interpro:IPR004401(Conserved hypothetical protein CHP00103)	refseq:NP_001186967.1|refseq:NP_766203.1|ensembl:ENSMUSG00000035629(gene)|ensembl:ENSMUST00000089684(transcript)|go:"GO:0002376"(immune system process)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005764"(lysosome)|go:"GO:0005769"(early endosome)|go:"GO:0005770"(late endosome)|go:"GO:0005829"(cytosol)|go:"GO:0006897"(endocytosis)|go:"GO:0006914"(autophagy)|go:"GO:0010507"(negative regulation of autophagy)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0043553"(negative regulation of phosphatidylinositol 3-kinase activity)|go:"GO:0045806"(negative regulation of endocytosis)|go:"GO:1901097"(negative regulation of autophagosome maturation)|go:"GO:1901981"(phosphatidylinositol phosphate binding)|interpro:IPR004012(RUN)|interpro:IPR025258|interpro:IPR037213|mint:Q80U62	-	-	-	figure legend:ST5|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2020/07/08	2020/08/14	rogid:BspTx2RZuhJaQ319NBDIyOreqfE83332	rogid:W9a7lLJWOl9czZuUTzBr+Nfyaqw10090	rigid:yJ/TD1qUaO9JUFby4AGqcC80ddU	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:O07422	uniprotkb:Q8K4B2	intact:EBI-25767563|uniprotkb:F2GLX6|uniprotkb:I6Y302|uniprotkb:Q7DAB9	intact:EBI-646179|uniprotkb:Q8C7U8|uniprotkb:Q8CE40|uniprotkb:Q8K1S8|ensembl:ENSMUSP00000020448	psi-mi:o07422_myctu(display_long)|uniprotkb:Rv0178(locus name)	psi-mi:irak3_mouse(display_long)|uniprotkb:IL-1 receptor-associated kinase M(gene name synonym)|uniprotkb:Irak3(gene name)|psi-mi:Irak3(display_short)|uniprotkb:Inactive IL-1 receptor-associated kinase 3(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2018)	doi:10.1093/nar/gkx1173|imex:IM-28235|pubmed:29165646	taxid:83332(myctu)|taxid:83332("Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)")	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0471"(MINT)	intact:EBI-25768056|imex:IM-28235-313	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	go:"GO:0005576"(extracellular region)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0051701"(biological process involved in interaction with host)|mint:O07422|refseq:NP_214692.1|refseq:WP_003899844.1	refseq:NP_082955.2|go:"GO:0001960"(negative regulation of cytokine-mediated signaling pathway)|go:"GO:0002755"(MyD88-dependent toll-like receptor signaling pathway)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0009615"(response to virus)|go:"GO:0010933"(positive regulation of macrophage tolerance induction)|go:"GO:0010936"(negative regulation of macrophage cytokine production)|go:"GO:0019221"(cytokine-mediated signaling pathway)|go:"GO:0019901"(protein kinase binding)|go:"GO:0032088"(negative regulation of NF-kappaB transcription factor activity)|go:"GO:0032494"(response to peptidoglycan)|go:"GO:0032496"(response to lipopolysaccharide)|go:"GO:0032695"(negative regulation of interleukin-12 production)|go:"GO:0032715"(negative regulation of interleukin-6 production)|go:"GO:0032720"(negative regulation of tumor necrosis factor production)|go:"GO:0034122"(negative regulation of toll-like receptor signaling pathway)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0042177"(negative regulation of protein catabolic process)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043242"(negative regulation of protein-containing complex disassembly)|go:"GO:0043244"(regulation of protein-containing complex disassembly)|go:"GO:0043330"(response to exogenous dsRNA)|go:"GO:0043407"(negative regulation of MAP kinase activity)|go:"GO:0045824"(negative regulation of innate immune response)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|go:"GO:0070498"(interleukin-1-mediated signaling pathway)|go:"GO:0070555"(response to interleukin-1)|interpro:IPR000488(Death)|interpro:IPR000719(Protein kinase, core)|interpro:IPR011009(Protein kinase-like)|interpro:IPR011029(DEATH-like)|interpro:IPR033610|interpro:IPR042698|interpro:IPR042747|mint:Q8K4B2|reactome:R-MMU-9020702|ensembl:ENSMUSG00000020227(gene)|ensembl:ENSMUST00000020448(transcript)|go:"GO:0000287"(magnesium ion binding)|go:"GO:0001819"(positive regulation of cytokine production)	-	-	-	figure legend:ST5|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2020/07/08	2020/08/14	rogid:lGOg72Osvz8819m674JzGUcHEj483332	rogid:oIjgqYFjr3oyFSGixSb2jrq03Cc10090	rigid:6GpocixLLSrNWcAbAEWyyzVLlyA	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P9WIT1	uniprotkb:Q80U62	intact:EBI-25767539|uniprotkb:L0TBU2|uniprotkb:Q50685|uniprotkb:Q7D7C5	intact:EBI-3506572|uniprotkb:Q3TAX3|uniprotkb:Q3TD96|uniprotkb:Q3TDF7|uniprotkb:Q3TDU2|uniprotkb:Q6NWW8|uniprotkb:Q6P9T7|uniprotkb:Q6PG18|uniprotkb:Q8BMP7|uniprotkb:Q8BY22|ensembl:ENSMUSP00000087114	psi-mi:y2280_myctu(display_long)|uniprotkb:Rv2280(locus name)	psi-mi:rubic_mouse(display_long)|uniprotkb:Rubcn(gene name)|psi-mi:Rubcn(display_short)|uniprotkb:Kiaa0226(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2018)	doi:10.1093/nar/gkx1173|imex:IM-28235|pubmed:29165646	taxid:83332(myctu)|taxid:83332("Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)")	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0471"(MINT)	intact:EBI-25768370|imex:IM-28235-243	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	go:"GO:0005618"(cell wall)|go:"GO:0005886"(plasma membrane)|go:"GO:0016491"(oxidoreductase activity)|go:"GO:0071949"(FAD binding)|interpro:IPR016169(CO dehydrogenase flavoprotein-like, FAD-binding, subdomain 2)|mint:P9WIT1|refseq:WP_003411690.1|interpro:IPR016166(FAD-binding, type 2)|interpro:IPR036318|interpro:IPR016164(FAD-linked oxidase-like, C-terminal)|interpro:IPR004113(FAD-linked oxidase, C-terminal)|interpro:IPR006094(FAD linked oxidase, N-terminal)|interpro:IPR016171(Vanillyl-alcohol oxidase, C-terminal subdomain 2)	refseq:NP_001186967.1|refseq:NP_766203.1|ensembl:ENSMUSG00000035629(gene)|ensembl:ENSMUST00000089684(transcript)|go:"GO:0002376"(immune system process)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005764"(lysosome)|go:"GO:0005769"(early endosome)|go:"GO:0005770"(late endosome)|go:"GO:0005829"(cytosol)|go:"GO:0006897"(endocytosis)|go:"GO:0006914"(autophagy)|go:"GO:0010507"(negative regulation of autophagy)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0043553"(negative regulation of phosphatidylinositol 3-kinase activity)|go:"GO:0045806"(negative regulation of endocytosis)|go:"GO:1901097"(negative regulation of autophagosome maturation)|go:"GO:1901981"(phosphatidylinositol phosphate binding)|interpro:IPR004012(RUN)|interpro:IPR025258|interpro:IPR037213|mint:Q80U62	-	-	-	figure legend:ST5|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2020/07/08	2020/08/14	rogid:TvFI3uuw9zREl1q0DeWIsHmCSEk83332	rogid:W9a7lLJWOl9czZuUTzBr+Nfyaqw10090	rigid:tXNm/W9icBxcMg8wSMoyt0pTRcg	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:O07177	uniprotkb:Q80U62	intact:EBI-25767633|uniprotkb:L0T5L4	intact:EBI-3506572|uniprotkb:Q3TAX3|uniprotkb:Q3TD96|uniprotkb:Q3TDF7|uniprotkb:Q3TDU2|uniprotkb:Q6NWW8|uniprotkb:Q6P9T7|uniprotkb:Q6PG18|uniprotkb:Q8BMP7|uniprotkb:Q8BY22|ensembl:ENSMUSP00000087114	psi-mi:mak1_myctu(display_long)|uniprotkb:mak(gene name)|psi-mi:mak(display_short)|uniprotkb:Maltose-1-phosphate synthase(gene name synonym)|uniprotkb:Rv0127(locus name)	psi-mi:rubic_mouse(display_long)|uniprotkb:Rubcn(gene name)|psi-mi:Rubcn(display_short)|uniprotkb:Kiaa0226(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2018)	doi:10.1093/nar/gkx1173|imex:IM-28235|pubmed:29165646	taxid:83332(myctu)|taxid:83332("Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)")	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0471"(MINT)	intact:EBI-25768364|imex:IM-28235-323	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	go:"GO:0005978"(glycogen biosynthetic process)|go:"GO:0005992"(trehalose biosynthetic process)|go:"GO:0016301"(kinase activity)|go:"GO:0046835"(carbohydrate phosphorylation)|rcsb pdb:4O7O|rcsb pdb:4O7P|go:"GO:0005524"(ATP binding)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|mint:O07177|refseq:NP_214641.1|refseq:WP_003916610.1|interpro:IPR011009(Protein kinase-like)|interpro:IPR040999	refseq:NP_001186967.1|refseq:NP_766203.1|ensembl:ENSMUSG00000035629(gene)|ensembl:ENSMUST00000089684(transcript)|go:"GO:0002376"(immune system process)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005764"(lysosome)|go:"GO:0005769"(early endosome)|go:"GO:0005770"(late endosome)|go:"GO:0005829"(cytosol)|go:"GO:0006897"(endocytosis)|go:"GO:0006914"(autophagy)|go:"GO:0010507"(negative regulation of autophagy)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0043553"(negative regulation of phosphatidylinositol 3-kinase activity)|go:"GO:0045806"(negative regulation of endocytosis)|go:"GO:1901097"(negative regulation of autophagosome maturation)|go:"GO:1901981"(phosphatidylinositol phosphate binding)|interpro:IPR004012(RUN)|interpro:IPR025258|interpro:IPR037213|mint:Q80U62	-	-	-	figure legend:ST5|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2020/07/08	2020/08/14	rogid:kpl6jZ4UbJUq/kfAlHBYpJAJV4E83332	rogid:W9a7lLJWOl9czZuUTzBr+Nfyaqw10090	rigid:ZGFqdVALjAULefM6GJAToCB5Mh0	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:L7N684	uniprotkb:Q80U62	intact:EBI-25768007|uniprotkb:I6XZY1	intact:EBI-3506572|uniprotkb:Q3TAX3|uniprotkb:Q3TD96|uniprotkb:Q3TDF7|uniprotkb:Q3TDU2|uniprotkb:Q6NWW8|uniprotkb:Q6P9T7|uniprotkb:Q6PG18|uniprotkb:Q8BMP7|uniprotkb:Q8BY22|ensembl:ENSMUSP00000087114	psi-mi:l7n684_myctu(display_long)|uniprotkb:Rv2141c(locus name)	psi-mi:rubic_mouse(display_long)|uniprotkb:Rubcn(gene name)|psi-mi:Rubcn(display_short)|uniprotkb:Kiaa0226(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2018)	doi:10.1093/nar/gkx1173|imex:IM-28235|pubmed:29165646	taxid:83332(myctu)|taxid:83332("Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)")	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0471"(MINT)	intact:EBI-25768358|imex:IM-28235-147	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	go:"GO:0006526"(arginine biosynthetic process)|go:"GO:0008777"(acetylornithine deacetylase activity)|mint:L7N684|refseq:WP_003411121.1|refseq:YP_177864.1|interpro:IPR001261(ArgE/DapE/ACY1/CPG2/YscS, conserved site)|interpro:IPR036264|interpro:IPR002933(Peptidase M20)|interpro:IPR011650(Peptidase M20, dimerisation)	refseq:NP_001186967.1|refseq:NP_766203.1|ensembl:ENSMUSG00000035629(gene)|ensembl:ENSMUST00000089684(transcript)|go:"GO:0002376"(immune system process)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005764"(lysosome)|go:"GO:0005769"(early endosome)|go:"GO:0005770"(late endosome)|go:"GO:0005829"(cytosol)|go:"GO:0006897"(endocytosis)|go:"GO:0006914"(autophagy)|go:"GO:0010507"(negative regulation of autophagy)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0043553"(negative regulation of phosphatidylinositol 3-kinase activity)|go:"GO:0045806"(negative regulation of endocytosis)|go:"GO:1901097"(negative regulation of autophagosome maturation)|go:"GO:1901981"(phosphatidylinositol phosphate binding)|interpro:IPR004012(RUN)|interpro:IPR025258|interpro:IPR037213|mint:Q80U62	-	-	-	figure legend:ST5|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2020/07/08	2020/08/14	rogid:c/gr5TMeB+nx0CZHLBZI7YeVioo83332	rogid:W9a7lLJWOl9czZuUTzBr+Nfyaqw10090	rigid:HjD/inbBFX5rLSeU3BlEwbBJdYI	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P9WN37	uniprotkb:Q80U62	intact:EBI-25767601|uniprotkb:L0T968|uniprotkb:P64245|uniprotkb:Q10378	intact:EBI-3506572|uniprotkb:Q3TAX3|uniprotkb:Q3TD96|uniprotkb:Q3TDF7|uniprotkb:Q3TDU2|uniprotkb:Q6NWW8|uniprotkb:Q6P9T7|uniprotkb:Q6PG18|uniprotkb:Q8BMP7|uniprotkb:Q8BY22|ensembl:ENSMUSP00000087114	psi-mi:gln1a_myctu(display_long)|uniprotkb:glnA2(gene name)|psi-mi:glnA2(display_short)|uniprotkb:Glutamate--ammonia ligase(gene name synonym)|uniprotkb:Glutamine synthetase I alpha(gene name synonym)|uniprotkb:MTCY190.33c(orf name)|uniprotkb:MTCY427.03c(orf name)|uniprotkb:Rv2222c(locus name)	psi-mi:rubic_mouse(display_long)|uniprotkb:Rubcn(gene name)|psi-mi:Rubcn(display_short)|uniprotkb:Kiaa0226(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2018)	doi:10.1093/nar/gkx1173|imex:IM-28235|pubmed:29165646	taxid:83332(myctu)|taxid:83332("Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)")	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0471"(MINT)	intact:EBI-25768352|imex:IM-28235-145	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	go:"GO:0004356"(glutamate-ammonia ligase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0006542"(glutamine biosynthetic process)|go:"GO:0046872"(metal ion binding)|go:"GO:0050001"(D-glutaminase activity)|mint:P9WN37|refseq:NP_216738.1|refseq:WP_003411482.1|interpro:IPR008147(Glutamine synthetase, beta-Grasp)|interpro:IPR036651|interpro:IPR014746(Glutamine synthetase/guanido kinase, catalytic region)|interpro:IPR008146(Glutamine synthetase, catalytic region)|interpro:IPR027303	refseq:NP_001186967.1|refseq:NP_766203.1|ensembl:ENSMUSG00000035629(gene)|ensembl:ENSMUST00000089684(transcript)|go:"GO:0002376"(immune system process)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005764"(lysosome)|go:"GO:0005769"(early endosome)|go:"GO:0005770"(late endosome)|go:"GO:0005829"(cytosol)|go:"GO:0006897"(endocytosis)|go:"GO:0006914"(autophagy)|go:"GO:0010507"(negative regulation of autophagy)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0043553"(negative regulation of phosphatidylinositol 3-kinase activity)|go:"GO:0045806"(negative regulation of endocytosis)|go:"GO:1901097"(negative regulation of autophagosome maturation)|go:"GO:1901981"(phosphatidylinositol phosphate binding)|interpro:IPR004012(RUN)|interpro:IPR025258|interpro:IPR037213|mint:Q80U62	-	-	-	figure legend:ST5|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2020/07/08	2020/08/14	rogid:LDIpolmw5yhv2iG5+8HKbWlwT8883332	rogid:W9a7lLJWOl9czZuUTzBr+Nfyaqw10090	rigid:KnLzBCOd5Ni4awqY4O0oJ2nsM4E	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P71619	uniprotkb:Q80U62	intact:EBI-25767582|uniprotkb:F2GLA0|uniprotkb:I6YAD4	intact:EBI-3506572|uniprotkb:Q3TAX3|uniprotkb:Q3TD96|uniprotkb:Q3TDF7|uniprotkb:Q3TDU2|uniprotkb:Q6NWW8|uniprotkb:Q6P9T7|uniprotkb:Q6PG18|uniprotkb:Q8BMP7|uniprotkb:Q8BY22|ensembl:ENSMUSP00000087114	psi-mi:p71619_myctu(display_long)|uniprotkb:ugpB(gene name)|psi-mi:ugpB(display_short)|uniprotkb:Rv2833c(locus name)	psi-mi:rubic_mouse(display_long)|uniprotkb:Rubcn(gene name)|psi-mi:Rubcn(display_short)|uniprotkb:Kiaa0226(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2018)	doi:10.1093/nar/gkx1173|imex:IM-28235|pubmed:29165646	taxid:83332(myctu)|taxid:83332("Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)")	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0471"(MINT)	intact:EBI-25768346|imex:IM-28235-193	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	go:"GO:0005886"(plasma membrane)|rcsb pdb:6R1B|mint:P71619|refseq:NP_217349.1|refseq:WP_003414501.1|interpro:IPR006059(Bacterial extracellular solute-binding, family 1)|interpro:IPR006311(Twin-arginine translocation pathway signal)	refseq:NP_001186967.1|refseq:NP_766203.1|ensembl:ENSMUSG00000035629(gene)|ensembl:ENSMUST00000089684(transcript)|go:"GO:0002376"(immune system process)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005764"(lysosome)|go:"GO:0005769"(early endosome)|go:"GO:0005770"(late endosome)|go:"GO:0005829"(cytosol)|go:"GO:0006897"(endocytosis)|go:"GO:0006914"(autophagy)|go:"GO:0010507"(negative regulation of autophagy)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0043553"(negative regulation of phosphatidylinositol 3-kinase activity)|go:"GO:0045806"(negative regulation of endocytosis)|go:"GO:1901097"(negative regulation of autophagosome maturation)|go:"GO:1901981"(phosphatidylinositol phosphate binding)|interpro:IPR004012(RUN)|interpro:IPR025258|interpro:IPR037213|mint:Q80U62	-	-	-	figure legend:ST5|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2020/07/08	2020/08/14	rogid:ldo4FA/3ddzSo1mfnNEPte27F1083332	rogid:W9a7lLJWOl9czZuUTzBr+Nfyaqw10090	rigid:LoN+7MXwTHj3pzkz5NZllnUSlgU	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:I6Y946	uniprotkb:Q04863	intact:EBI-25767727	intact:EBI-1209145|uniprotkb:Q8VE46|ensembl:ENSMUSP00000092355|ensembl:ENSMUSP00000096350	psi-mi:i6y946_myctu(display_long)|uniprotkb:Rv0925c(locus name)	psi-mi:relb_mouse(display_long)|uniprotkb:Relb(gene name)|psi-mi:Relb(display_short)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2018)	doi:10.1093/nar/gkx1173|imex:IM-28235|pubmed:29165646	taxid:83332(myctu)|taxid:83332("Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)")	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0471"(MINT)	intact:EBI-25768340|imex:IM-28235-191	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	go:"GO:0016491"(oxidoreductase activity)|mint:I6Y946|refseq:NP_215440.1|refseq:WP_003404764.1|interpro:IPR029039|interpro:IPR005025(NADPH-dependent FMN reductase)	refseq:NP_033072.2|refseq:NP_001277386.1|dip:DIP-39585N|interpro:IPR008967(p53-like transcription factor, DNA-binding)|interpro:IPR011539(Rel homology)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR014756(Immunoglobulin E-set)|interpro:IPR030492|interpro:IPR030496|interpro:IPR032397|interpro:IPR032399|interpro:IPR032400|interpro:IPR033926|interpro:IPR037059|mint:Q04863|rcsb pdb:1ZK9|rcsb pdb:1ZKA|rcsb pdb:2V2T|rcsb pdb:3DO7|rcsb pdb:3JSS|rcsb pdb:3JUZ|rcsb pdb:3JV0|go:"GO:0032922"(circadian regulation of gene expression)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034097"(response to cytokine)|rcsb pdb:3JV4|go:"GO:0038061"(NIK/NF-kappaB signaling)|go:"GO:0042088"(T-helper 1 type immune response)|go:"GO:0042802"(identical protein binding)|go:"GO:0043011"(myeloid dendritic cell differentiation)|rcsb pdb:3JV6|go:"GO:0045063"(T-helper 1 cell differentiation)|go:"GO:0045087"(innate immune response)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0071470"(cellular response to osmotic stress)|interpro:IPR000451(NF-kappa-B/Rel/dorsal)|interpro:IPR002909(Cell surface receptor IPT/TIG)|rcsb pdb:4JGM|rcsb pdb:4JHB|reactome:R-MMU-5607761|reactome:R-MMU-5621575|reactome:R-MMU-5676590|ensembl:ENSMUSG00000002983(gene)|ensembl:ENSMUST00000094762(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006954"(inflammatory response)|go:"GO:0007249"(I-kappaB kinase/NF-kappaB signaling)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0017053"(transcription repressor complex)|go:"GO:0019882"(antigen processing and presentation)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030098"(lymphocyte differentiation)|go:"GO:0032688"(negative regulation of interferon-beta production)|ensembl:ENSMUST00000098754(transcript)	-	-	-	figure legend:ST5|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2020/07/08	2020/08/14	rogid:JOW06LtizimdrjJdMmMnM9ru8n083332	rogid:yAyr1pDl4QbPqNTWkL+dlygSiFA10090	rigid:Jf2GcjHj9+/hKzWe2gx36/PS+mI	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P9WP17	uniprotkb:Q04863	intact:EBI-25767691|uniprotkb:L0T3B0|uniprotkb:O07247	intact:EBI-1209145|uniprotkb:Q8VE46|ensembl:ENSMUSP00000092355|ensembl:ENSMUSP00000096350	psi-mi:dcdb_myctu(display_long)|uniprotkb:dcd(gene name)|psi-mi:dcd(display_short)|uniprotkb:"Bifunctional dCTP deaminase:dUTPase"(gene name synonym)|uniprotkb:DCD-DUT(gene name synonym)|uniprotkb:MTCY63.26(orf name)|uniprotkb:Rv0321(locus name)	psi-mi:relb_mouse(display_long)|uniprotkb:Relb(gene name)|psi-mi:Relb(display_short)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2018)	doi:10.1093/nar/gkx1173|imex:IM-28235|pubmed:29165646	taxid:83332(myctu)|taxid:83332("Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)")	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0471"(MINT)	intact:EBI-25768334|imex:IM-28235-91	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	go:"GO:0000166"(nucleotide binding)|go:"GO:0004170"(dUTP diphosphatase activity)|go:"GO:0006226"(dUMP biosynthetic process)|go:"GO:0006229"(dUTP biosynthetic process)|go:"GO:0008829"(dCTP deaminase activity)|go:"GO:0015949"(nucleobase-containing small molecule interconversion)|go:"GO:0033973"("dCTP deaminase (dUMP-forming) activity")|rcsb pdb:2QLP|rcsb pdb:2QXX|rcsb pdb:4A6A|mint:P9WP17|refseq:NP_214835.1|refseq:WP_003898399.1|interpro:IPR011962(Deoxycytidine triphosphate deaminase)|interpro:IPR029054|interpro:IPR036157|interpro:IPR033704	refseq:NP_033072.2|refseq:NP_001277386.1|dip:DIP-39585N|interpro:IPR008967(p53-like transcription factor, DNA-binding)|interpro:IPR011539(Rel homology)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR014756(Immunoglobulin E-set)|interpro:IPR030492|interpro:IPR030496|interpro:IPR032397|interpro:IPR032399|interpro:IPR032400|interpro:IPR033926|interpro:IPR037059|mint:Q04863|rcsb pdb:1ZK9|rcsb pdb:1ZKA|rcsb pdb:2V2T|rcsb pdb:3DO7|rcsb pdb:3JSS|rcsb pdb:3JUZ|rcsb pdb:3JV0|go:"GO:0032922"(circadian regulation of gene expression)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034097"(response to cytokine)|rcsb pdb:3JV4|go:"GO:0038061"(NIK/NF-kappaB signaling)|go:"GO:0042088"(T-helper 1 type immune response)|go:"GO:0042802"(identical protein binding)|go:"GO:0043011"(myeloid dendritic cell differentiation)|rcsb pdb:3JV6|go:"GO:0045063"(T-helper 1 cell differentiation)|go:"GO:0045087"(innate immune response)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0071470"(cellular response to osmotic stress)|interpro:IPR000451(NF-kappa-B/Rel/dorsal)|interpro:IPR002909(Cell surface receptor IPT/TIG)|rcsb pdb:4JGM|rcsb pdb:4JHB|reactome:R-MMU-5607761|reactome:R-MMU-5621575|reactome:R-MMU-5676590|ensembl:ENSMUSG00000002983(gene)|ensembl:ENSMUST00000094762(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006954"(inflammatory response)|go:"GO:0007249"(I-kappaB kinase/NF-kappaB signaling)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0017053"(transcription repressor complex)|go:"GO:0019882"(antigen processing and presentation)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030098"(lymphocyte differentiation)|go:"GO:0032688"(negative regulation of interferon-beta production)|ensembl:ENSMUST00000098754(transcript)	-	-	-	figure legend:ST5|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2020/07/08	2020/08/14	rogid:7Llq0DbdMabIKeH06jyXlfJfD3083332	rogid:yAyr1pDl4QbPqNTWkL+dlygSiFA10090	rigid:RvCli/BIGhV1O+xT8xABhYtl3Dc	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P9WK51	uniprotkb:Q04863	intact:EBI-25767833|uniprotkb:L0T6D1|uniprotkb:Q11013	intact:EBI-1209145|uniprotkb:Q8VE46|ensembl:ENSMUSP00000092355|ensembl:ENSMUSP00000096350	psi-mi:lprd_myctu(display_long)|uniprotkb:lprD(gene name)|psi-mi:lprD(display_short)|uniprotkb:MTCY02B10.07c(orf name)|uniprotkb:Rv1343c(locus name)	psi-mi:relb_mouse(display_long)|uniprotkb:Relb(gene name)|psi-mi:Relb(display_short)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2018)	doi:10.1093/nar/gkx1173|imex:IM-28235|pubmed:29165646	taxid:83332(myctu)|taxid:83332("Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)")	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0471"(MINT)	intact:EBI-25768328|imex:IM-28235-143	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	go:"GO:0005886"(plasma membrane)|go:"GO:0016021"(integral component of membrane)|mint:P9WK51|refseq:NP_215859.1|refseq:WP_003898833.1	refseq:NP_033072.2|refseq:NP_001277386.1|dip:DIP-39585N|interpro:IPR008967(p53-like transcription factor, DNA-binding)|interpro:IPR011539(Rel homology)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR014756(Immunoglobulin E-set)|interpro:IPR030492|interpro:IPR030496|interpro:IPR032397|interpro:IPR032399|interpro:IPR032400|interpro:IPR033926|interpro:IPR037059|mint:Q04863|rcsb pdb:1ZK9|rcsb pdb:1ZKA|rcsb pdb:2V2T|rcsb pdb:3DO7|rcsb pdb:3JSS|rcsb pdb:3JUZ|rcsb pdb:3JV0|go:"GO:0032922"(circadian regulation of gene expression)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034097"(response to cytokine)|rcsb pdb:3JV4|go:"GO:0038061"(NIK/NF-kappaB signaling)|go:"GO:0042088"(T-helper 1 type immune response)|go:"GO:0042802"(identical protein binding)|go:"GO:0043011"(myeloid dendritic cell differentiation)|rcsb pdb:3JV6|go:"GO:0045063"(T-helper 1 cell differentiation)|go:"GO:0045087"(innate immune response)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0071470"(cellular response to osmotic stress)|interpro:IPR000451(NF-kappa-B/Rel/dorsal)|interpro:IPR002909(Cell surface receptor IPT/TIG)|rcsb pdb:4JGM|rcsb pdb:4JHB|reactome:R-MMU-5607761|reactome:R-MMU-5621575|reactome:R-MMU-5676590|ensembl:ENSMUSG00000002983(gene)|ensembl:ENSMUST00000094762(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006954"(inflammatory response)|go:"GO:0007249"(I-kappaB kinase/NF-kappaB signaling)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0017053"(transcription repressor complex)|go:"GO:0019882"(antigen processing and presentation)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030098"(lymphocyte differentiation)|go:"GO:0032688"(negative regulation of interferon-beta production)|ensembl:ENSMUST00000098754(transcript)	-	-	-	figure legend:ST5|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2020/07/08	2020/08/14	rogid:QGgZnt1zIKg1cEke5AZWZKM7Za483332	rogid:yAyr1pDl4QbPqNTWkL+dlygSiFA10090	rigid:XAq1R3ePqwHkfJFZY+pHMlzOcV8	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P9WJB9	uniprotkb:Q04863	intact:EBI-25767670|uniprotkb:L0TE21|uniprotkb:O69744|uniprotkb:Q7D4P0	intact:EBI-1209145|uniprotkb:Q8VE46|ensembl:ENSMUSP00000092355|ensembl:ENSMUSP00000096350	psi-mi:espl_myctu(display_long)|uniprotkb:espL(gene name)|psi-mi:espL(display_short)|uniprotkb:Rv3880c(locus name)	psi-mi:relb_mouse(display_long)|uniprotkb:Relb(gene name)|psi-mi:Relb(display_short)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2018)	doi:10.1093/nar/gkx1173|imex:IM-28235|pubmed:29165646	taxid:83332(myctu)|taxid:83332("Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)")	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0471"(MINT)	intact:EBI-25768322|imex:IM-28235-189	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	go:"GO:0003677"(DNA binding)|go:"GO:0005618"(cell wall)|go:"GO:0005886"(plasma membrane)|go:"GO:0052170"(suppression by symbiont of host innate immune response)|mint:P9WJB9|refseq:NP_218397.1|refseq:WP_003399988.1|interpro:IPR036894|interpro:IPR004401(Conserved hypothetical protein CHP00103)	refseq:NP_033072.2|refseq:NP_001277386.1|dip:DIP-39585N|interpro:IPR008967(p53-like transcription factor, DNA-binding)|interpro:IPR011539(Rel homology)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR014756(Immunoglobulin E-set)|interpro:IPR030492|interpro:IPR030496|interpro:IPR032397|interpro:IPR032399|interpro:IPR032400|interpro:IPR033926|interpro:IPR037059|mint:Q04863|rcsb pdb:1ZK9|rcsb pdb:1ZKA|rcsb pdb:2V2T|rcsb pdb:3DO7|rcsb pdb:3JSS|rcsb pdb:3JUZ|rcsb pdb:3JV0|go:"GO:0032922"(circadian regulation of gene expression)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034097"(response to cytokine)|rcsb pdb:3JV4|go:"GO:0038061"(NIK/NF-kappaB signaling)|go:"GO:0042088"(T-helper 1 type immune response)|go:"GO:0042802"(identical protein binding)|go:"GO:0043011"(myeloid dendritic cell differentiation)|rcsb pdb:3JV6|go:"GO:0045063"(T-helper 1 cell differentiation)|go:"GO:0045087"(innate immune response)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0071470"(cellular response to osmotic stress)|interpro:IPR000451(NF-kappa-B/Rel/dorsal)|interpro:IPR002909(Cell surface receptor IPT/TIG)|rcsb pdb:4JGM|rcsb pdb:4JHB|reactome:R-MMU-5607761|reactome:R-MMU-5621575|reactome:R-MMU-5676590|ensembl:ENSMUSG00000002983(gene)|ensembl:ENSMUST00000094762(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006954"(inflammatory response)|go:"GO:0007249"(I-kappaB kinase/NF-kappaB signaling)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0017053"(transcription repressor complex)|go:"GO:0019882"(antigen processing and presentation)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030098"(lymphocyte differentiation)|go:"GO:0032688"(negative regulation of interferon-beta production)|ensembl:ENSMUST00000098754(transcript)	-	-	-	figure legend:ST5|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2020/07/08	2020/08/14	rogid:BspTx2RZuhJaQ319NBDIyOreqfE83332	rogid:yAyr1pDl4QbPqNTWkL+dlygSiFA10090	rigid:J5DVxyzFGk4hjLfbCYe8gGQEOS4	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:O07177	uniprotkb:Q04863	intact:EBI-25767633|uniprotkb:L0T5L4	intact:EBI-1209145|uniprotkb:Q8VE46|ensembl:ENSMUSP00000092355|ensembl:ENSMUSP00000096350	psi-mi:mak1_myctu(display_long)|uniprotkb:mak(gene name)|psi-mi:mak(display_short)|uniprotkb:Maltose-1-phosphate synthase(gene name synonym)|uniprotkb:Rv0127(locus name)	psi-mi:relb_mouse(display_long)|uniprotkb:Relb(gene name)|psi-mi:Relb(display_short)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2018)	doi:10.1093/nar/gkx1173|imex:IM-28235|pubmed:29165646	taxid:83332(myctu)|taxid:83332("Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)")	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0471"(MINT)	intact:EBI-25768316|imex:IM-28235-321	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	go:"GO:0005978"(glycogen biosynthetic process)|go:"GO:0005992"(trehalose biosynthetic process)|go:"GO:0016301"(kinase activity)|go:"GO:0046835"(carbohydrate phosphorylation)|rcsb pdb:4O7O|rcsb pdb:4O7P|go:"GO:0005524"(ATP binding)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|mint:O07177|refseq:NP_214641.1|refseq:WP_003916610.1|interpro:IPR011009(Protein kinase-like)|interpro:IPR040999	refseq:NP_033072.2|refseq:NP_001277386.1|dip:DIP-39585N|interpro:IPR008967(p53-like transcription factor, DNA-binding)|interpro:IPR011539(Rel homology)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR014756(Immunoglobulin E-set)|interpro:IPR030492|interpro:IPR030496|interpro:IPR032397|interpro:IPR032399|interpro:IPR032400|interpro:IPR033926|interpro:IPR037059|mint:Q04863|rcsb pdb:1ZK9|rcsb pdb:1ZKA|rcsb pdb:2V2T|rcsb pdb:3DO7|rcsb pdb:3JSS|rcsb pdb:3JUZ|rcsb pdb:3JV0|go:"GO:0032922"(circadian regulation of gene expression)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034097"(response to cytokine)|rcsb pdb:3JV4|go:"GO:0038061"(NIK/NF-kappaB signaling)|go:"GO:0042088"(T-helper 1 type immune response)|go:"GO:0042802"(identical protein binding)|go:"GO:0043011"(myeloid dendritic cell differentiation)|rcsb pdb:3JV6|go:"GO:0045063"(T-helper 1 cell differentiation)|go:"GO:0045087"(innate immune response)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0071470"(cellular response to osmotic stress)|interpro:IPR000451(NF-kappa-B/Rel/dorsal)|interpro:IPR002909(Cell surface receptor IPT/TIG)|rcsb pdb:4JGM|rcsb pdb:4JHB|reactome:R-MMU-5607761|reactome:R-MMU-5621575|reactome:R-MMU-5676590|ensembl:ENSMUSG00000002983(gene)|ensembl:ENSMUST00000094762(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006954"(inflammatory response)|go:"GO:0007249"(I-kappaB kinase/NF-kappaB signaling)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0017053"(transcription repressor complex)|go:"GO:0019882"(antigen processing and presentation)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030098"(lymphocyte differentiation)|go:"GO:0032688"(negative regulation of interferon-beta production)|ensembl:ENSMUST00000098754(transcript)	-	-	-	figure legend:ST5|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2020/07/08	2020/08/14	rogid:kpl6jZ4UbJUq/kfAlHBYpJAJV4E83332	rogid:yAyr1pDl4QbPqNTWkL+dlygSiFA10090	rigid:3M6bm21WYo6Co/o5NPJda7xYbDg	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P71619	uniprotkb:Q04863	intact:EBI-25767582|uniprotkb:F2GLA0|uniprotkb:I6YAD4	intact:EBI-1209145|uniprotkb:Q8VE46|ensembl:ENSMUSP00000092355|ensembl:ENSMUSP00000096350	psi-mi:p71619_myctu(display_long)|uniprotkb:ugpB(gene name)|psi-mi:ugpB(display_short)|uniprotkb:Rv2833c(locus name)	psi-mi:relb_mouse(display_long)|uniprotkb:Relb(gene name)|psi-mi:Relb(display_short)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2018)	doi:10.1093/nar/gkx1173|imex:IM-28235|pubmed:29165646	taxid:83332(myctu)|taxid:83332("Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)")	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0471"(MINT)	intact:EBI-25768310|imex:IM-28235-65	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	go:"GO:0005886"(plasma membrane)|rcsb pdb:6R1B|mint:P71619|refseq:NP_217349.1|refseq:WP_003414501.1|interpro:IPR006059(Bacterial extracellular solute-binding, family 1)|interpro:IPR006311(Twin-arginine translocation pathway signal)	refseq:NP_033072.2|refseq:NP_001277386.1|dip:DIP-39585N|interpro:IPR008967(p53-like transcription factor, DNA-binding)|interpro:IPR011539(Rel homology)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR014756(Immunoglobulin E-set)|interpro:IPR030492|interpro:IPR030496|interpro:IPR032397|interpro:IPR032399|interpro:IPR032400|interpro:IPR033926|interpro:IPR037059|mint:Q04863|rcsb pdb:1ZK9|rcsb pdb:1ZKA|rcsb pdb:2V2T|rcsb pdb:3DO7|rcsb pdb:3JSS|rcsb pdb:3JUZ|rcsb pdb:3JV0|go:"GO:0032922"(circadian regulation of gene expression)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034097"(response to cytokine)|rcsb pdb:3JV4|go:"GO:0038061"(NIK/NF-kappaB signaling)|go:"GO:0042088"(T-helper 1 type immune response)|go:"GO:0042802"(identical protein binding)|go:"GO:0043011"(myeloid dendritic cell differentiation)|rcsb pdb:3JV6|go:"GO:0045063"(T-helper 1 cell differentiation)|go:"GO:0045087"(innate immune response)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0071470"(cellular response to osmotic stress)|interpro:IPR000451(NF-kappa-B/Rel/dorsal)|interpro:IPR002909(Cell surface receptor IPT/TIG)|rcsb pdb:4JGM|rcsb pdb:4JHB|reactome:R-MMU-5607761|reactome:R-MMU-5621575|reactome:R-MMU-5676590|ensembl:ENSMUSG00000002983(gene)|ensembl:ENSMUST00000094762(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006954"(inflammatory response)|go:"GO:0007249"(I-kappaB kinase/NF-kappaB signaling)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0017053"(transcription repressor complex)|go:"GO:0019882"(antigen processing and presentation)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030098"(lymphocyte differentiation)|go:"GO:0032688"(negative regulation of interferon-beta production)|ensembl:ENSMUST00000098754(transcript)	-	-	-	figure legend:ST5|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2020/07/08	2020/08/14	rogid:ldo4FA/3ddzSo1mfnNEPte27F1083332	rogid:yAyr1pDl4QbPqNTWkL+dlygSiFA10090	rigid:2kyxWcz60dJqZPmRbG4p0g3HIL8	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:I6Y946	uniprotkb:Q9Z1S3	intact:EBI-25767727	intact:EBI-25768217|ensembl:ENSMUSP00000099593|ensembl:ENSMUSP00000136423|uniprotkb:Q3V401|uniprotkb:Q8BQP6|uniprotkb:Q3URH0	psi-mi:i6y946_myctu(display_long)|uniprotkb:Rv0925c(locus name)	psi-mi:grp1_mouse(display_long)|uniprotkb:Rasgrp1(gene name)|psi-mi:Rasgrp1(display_short)|uniprotkb:Rasgrp(gene name synonym)|uniprotkb:Calcium and DAG-regulated guanine nucleotide exchange factor II(gene name synonym)|uniprotkb:Ras guanyl-releasing protein(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2018)	doi:10.1093/nar/gkx1173|imex:IM-28235|pubmed:29165646	taxid:83332(myctu)|taxid:83332("Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)")	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0471"(MINT)	intact:EBI-25768304|imex:IM-28235-241	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	go:"GO:0016491"(oxidoreductase activity)|mint:I6Y946|refseq:NP_215440.1|refseq:WP_003404764.1|interpro:IPR029039|interpro:IPR005025(NADPH-dependent FMN reductase)	ensembl:ENSMUSG00000027347(gene)|ensembl:ENSMUST00000102534(transcript)|ensembl:ENSMUST00000178884(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001934"(positive regulation of protein phosphorylation)|go:"GO:0002437"(inflammatory response to antigenic stimulus)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0007264"(small GTPase mediated signal transduction)|go:"GO:0008270"(zinc ion binding)|go:"GO:0014066"(regulation of phosphatidylinositol 3-kinase signaling)|go:"GO:0019992"(diacylglycerol binding)|go:"GO:0030101"(natural killer cell activation)|go:"GO:0030154"(cell differentiation)|go:"GO:0031210"(phosphatidylcholine binding)|go:"GO:0032252"(secretory granule localization)|go:"GO:0032725"(positive regulation of granulocyte macrophage colony-stimulating factor production)|go:"GO:0032729"(positive regulation of interferon-gamma production)|go:"GO:0032760"(positive regulation of tumor necrosis factor production)|go:"GO:0032816"(positive regulation of natural killer cell activation)|go:"GO:0033089"(positive regulation of T cell differentiation in thymus)|go:"GO:0042098"(T cell proliferation)|go:"GO:0042100"(B cell proliferation)|go:"GO:0042110"(T cell activation)|go:"GO:0042113"(B cell activation)|go:"GO:0042802"(identical protein binding)|go:"GO:0043303"(mast cell degranulation)|go:"GO:0043406"(positive regulation of MAP kinase activity)|go:"GO:0043547"(positive regulation of GTPase activity)|go:"GO:0045954"(positive regulation of natural killer cell mediated cytotoxicity)|go:"GO:0046330"(positive regulation of JNK cascade)|go:"GO:0046579"(positive regulation of Ras protein signal transduction)|go:"GO:0047496"(vesicle transport along microtubule)|go:"GO:0070372"(regulation of ERK1 and ERK2 cascade)|go:"GO:0070374"(positive regulation of ERK1 and ERK2 cascade)|go:"GO:0090630"(activation of GTPase activity)|interpro:IPR000651(Guanine nucleotide exchange factor for Ras-like GTPases, N-terminal)|interpro:IPR001895(Guanine-nucleotide dissociation stimulator CDC25)|interpro:IPR002048(Calcium-binding EF-hand)|interpro:IPR002219(Protein kinase C, phorbol ester/diacylglycerol binding)|interpro:IPR008937(Ras guanine nucleotide exchange factor)|interpro:IPR011992(EF-Hand type)|interpro:IPR018247|interpro:IPR020454|interpro:IPR023578|interpro:IPR036964|mint:Q9Z1S3|reactome:R-MMU-1169092|reactome:R-MMU-354192|reactome:R-MMU-392517|reactome:R-MMU-5673001|go:"GO:0032825"(positive regulation of natural killer cell differentiation)|refseq:NP_035376.1	-	-	-	figure legend:ST5|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2020/07/08	2020/08/14	rogid:JOW06LtizimdrjJdMmMnM9ru8n083332	rogid:cwPdbX3JNZhbDXCk8v0xWa/ixgY10090	rigid:JuunnL2EwXAve2OoMNr4dZzSH4M	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P9WJB9	uniprotkb:Q9Z1S3	intact:EBI-25767670|uniprotkb:L0TE21|uniprotkb:O69744|uniprotkb:Q7D4P0	intact:EBI-25768217|ensembl:ENSMUSP00000099593|ensembl:ENSMUSP00000136423|uniprotkb:Q3V401|uniprotkb:Q8BQP6|uniprotkb:Q3URH0	psi-mi:espl_myctu(display_long)|uniprotkb:espL(gene name)|psi-mi:espL(display_short)|uniprotkb:Rv3880c(locus name)	psi-mi:grp1_mouse(display_long)|uniprotkb:Rasgrp1(gene name)|psi-mi:Rasgrp1(display_short)|uniprotkb:Rasgrp(gene name synonym)|uniprotkb:Calcium and DAG-regulated guanine nucleotide exchange factor II(gene name synonym)|uniprotkb:Ras guanyl-releasing protein(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2018)	doi:10.1093/nar/gkx1173|imex:IM-28235|pubmed:29165646	taxid:83332(myctu)|taxid:83332("Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)")	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0471"(MINT)	intact:EBI-25768298|imex:IM-28235-275	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	go:"GO:0003677"(DNA binding)|go:"GO:0005618"(cell wall)|go:"GO:0005886"(plasma membrane)|go:"GO:0052170"(suppression by symbiont of host innate immune response)|mint:P9WJB9|refseq:NP_218397.1|refseq:WP_003399988.1|interpro:IPR036894|interpro:IPR004401(Conserved hypothetical protein CHP00103)	ensembl:ENSMUSG00000027347(gene)|ensembl:ENSMUST00000102534(transcript)|ensembl:ENSMUST00000178884(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001934"(positive regulation of protein phosphorylation)|go:"GO:0002437"(inflammatory response to antigenic stimulus)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0007264"(small GTPase mediated signal transduction)|go:"GO:0008270"(zinc ion binding)|go:"GO:0014066"(regulation of phosphatidylinositol 3-kinase signaling)|go:"GO:0019992"(diacylglycerol binding)|go:"GO:0030101"(natural killer cell activation)|go:"GO:0030154"(cell differentiation)|go:"GO:0031210"(phosphatidylcholine binding)|go:"GO:0032252"(secretory granule localization)|go:"GO:0032725"(positive regulation of granulocyte macrophage colony-stimulating factor production)|go:"GO:0032729"(positive regulation of interferon-gamma production)|go:"GO:0032760"(positive regulation of tumor necrosis factor production)|go:"GO:0032816"(positive regulation of natural killer cell activation)|go:"GO:0033089"(positive regulation of T cell differentiation in thymus)|go:"GO:0042098"(T cell proliferation)|go:"GO:0042100"(B cell proliferation)|go:"GO:0042110"(T cell activation)|go:"GO:0042113"(B cell activation)|go:"GO:0042802"(identical protein binding)|go:"GO:0043303"(mast cell degranulation)|go:"GO:0043406"(positive regulation of MAP kinase activity)|go:"GO:0043547"(positive regulation of GTPase activity)|go:"GO:0045954"(positive regulation of natural killer cell mediated cytotoxicity)|go:"GO:0046330"(positive regulation of JNK cascade)|go:"GO:0046579"(positive regulation of Ras protein signal transduction)|go:"GO:0047496"(vesicle transport along microtubule)|go:"GO:0070372"(regulation of ERK1 and ERK2 cascade)|go:"GO:0070374"(positive regulation of ERK1 and ERK2 cascade)|go:"GO:0090630"(activation of GTPase activity)|interpro:IPR000651(Guanine nucleotide exchange factor for Ras-like GTPases, N-terminal)|interpro:IPR001895(Guanine-nucleotide dissociation stimulator CDC25)|interpro:IPR002048(Calcium-binding EF-hand)|interpro:IPR002219(Protein kinase C, phorbol ester/diacylglycerol binding)|interpro:IPR008937(Ras guanine nucleotide exchange factor)|interpro:IPR011992(EF-Hand type)|interpro:IPR018247|interpro:IPR020454|interpro:IPR023578|interpro:IPR036964|mint:Q9Z1S3|reactome:R-MMU-1169092|reactome:R-MMU-354192|reactome:R-MMU-392517|reactome:R-MMU-5673001|go:"GO:0032825"(positive regulation of natural killer cell differentiation)|refseq:NP_035376.1	-	-	-	figure legend:ST5|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2020/07/08	2020/08/14	rogid:BspTx2RZuhJaQ319NBDIyOreqfE83332	rogid:cwPdbX3JNZhbDXCk8v0xWa/ixgY10090	rigid:NPL65ac4BiHvvGyZuJmfr9R22is	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P9WIT1	uniprotkb:Q9Z1S3	intact:EBI-25767539|uniprotkb:L0TBU2|uniprotkb:Q50685|uniprotkb:Q7D7C5	intact:EBI-25768217|ensembl:ENSMUSP00000099593|ensembl:ENSMUSP00000136423|uniprotkb:Q3V401|uniprotkb:Q8BQP6|uniprotkb:Q3URH0	psi-mi:y2280_myctu(display_long)|uniprotkb:Rv2280(locus name)	psi-mi:grp1_mouse(display_long)|uniprotkb:Rasgrp1(gene name)|psi-mi:Rasgrp1(display_short)|uniprotkb:Rasgrp(gene name synonym)|uniprotkb:Calcium and DAG-regulated guanine nucleotide exchange factor II(gene name synonym)|uniprotkb:Ras guanyl-releasing protein(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2018)	doi:10.1093/nar/gkx1173|imex:IM-28235|pubmed:29165646	taxid:83332(myctu)|taxid:83332("Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)")	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0471"(MINT)	intact:EBI-25768292|imex:IM-28235-15	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	go:"GO:0005618"(cell wall)|go:"GO:0005886"(plasma membrane)|go:"GO:0016491"(oxidoreductase activity)|go:"GO:0071949"(FAD binding)|interpro:IPR016169(CO dehydrogenase flavoprotein-like, FAD-binding, subdomain 2)|mint:P9WIT1|refseq:WP_003411690.1|interpro:IPR016166(FAD-binding, type 2)|interpro:IPR036318|interpro:IPR016164(FAD-linked oxidase-like, C-terminal)|interpro:IPR004113(FAD-linked oxidase, C-terminal)|interpro:IPR006094(FAD linked oxidase, N-terminal)|interpro:IPR016171(Vanillyl-alcohol oxidase, C-terminal subdomain 2)	ensembl:ENSMUSG00000027347(gene)|ensembl:ENSMUST00000102534(transcript)|ensembl:ENSMUST00000178884(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001934"(positive regulation of protein phosphorylation)|go:"GO:0002437"(inflammatory response to antigenic stimulus)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0007264"(small GTPase mediated signal transduction)|go:"GO:0008270"(zinc ion binding)|go:"GO:0014066"(regulation of phosphatidylinositol 3-kinase signaling)|go:"GO:0019992"(diacylglycerol binding)|go:"GO:0030101"(natural killer cell activation)|go:"GO:0030154"(cell differentiation)|go:"GO:0031210"(phosphatidylcholine binding)|go:"GO:0032252"(secretory granule localization)|go:"GO:0032725"(positive regulation of granulocyte macrophage colony-stimulating factor production)|go:"GO:0032729"(positive regulation of interferon-gamma production)|go:"GO:0032760"(positive regulation of tumor necrosis factor production)|go:"GO:0032816"(positive regulation of natural killer cell activation)|go:"GO:0033089"(positive regulation of T cell differentiation in thymus)|go:"GO:0042098"(T cell proliferation)|go:"GO:0042100"(B cell proliferation)|go:"GO:0042110"(T cell activation)|go:"GO:0042113"(B cell activation)|go:"GO:0042802"(identical protein binding)|go:"GO:0043303"(mast cell degranulation)|go:"GO:0043406"(positive regulation of MAP kinase activity)|go:"GO:0043547"(positive regulation of GTPase activity)|go:"GO:0045954"(positive regulation of natural killer cell mediated cytotoxicity)|go:"GO:0046330"(positive regulation of JNK cascade)|go:"GO:0046579"(positive regulation of Ras protein signal transduction)|go:"GO:0047496"(vesicle transport along microtubule)|go:"GO:0070372"(regulation of ERK1 and ERK2 cascade)|go:"GO:0070374"(positive regulation of ERK1 and ERK2 cascade)|go:"GO:0090630"(activation of GTPase activity)|interpro:IPR000651(Guanine nucleotide exchange factor for Ras-like GTPases, N-terminal)|interpro:IPR001895(Guanine-nucleotide dissociation stimulator CDC25)|interpro:IPR002048(Calcium-binding EF-hand)|interpro:IPR002219(Protein kinase C, phorbol ester/diacylglycerol binding)|interpro:IPR008937(Ras guanine nucleotide exchange factor)|interpro:IPR011992(EF-Hand type)|interpro:IPR018247|interpro:IPR020454|interpro:IPR023578|interpro:IPR036964|mint:Q9Z1S3|reactome:R-MMU-1169092|reactome:R-MMU-354192|reactome:R-MMU-392517|reactome:R-MMU-5673001|go:"GO:0032825"(positive regulation of natural killer cell differentiation)|refseq:NP_035376.1	-	-	-	figure legend:ST5|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2020/07/08	2020/08/14	rogid:TvFI3uuw9zREl1q0DeWIsHmCSEk83332	rogid:cwPdbX3JNZhbDXCk8v0xWa/ixgY10090	rigid:G3eOCRmkWC+Df2gZE6xcQItS6+A	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:O07177	uniprotkb:Q9Z1S3	intact:EBI-25767633|uniprotkb:L0T5L4	intact:EBI-25768217|ensembl:ENSMUSP00000099593|ensembl:ENSMUSP00000136423|uniprotkb:Q3V401|uniprotkb:Q8BQP6|uniprotkb:Q3URH0	psi-mi:mak1_myctu(display_long)|uniprotkb:mak(gene name)|psi-mi:mak(display_short)|uniprotkb:Maltose-1-phosphate synthase(gene name synonym)|uniprotkb:Rv0127(locus name)	psi-mi:grp1_mouse(display_long)|uniprotkb:Rasgrp1(gene name)|psi-mi:Rasgrp1(display_short)|uniprotkb:Rasgrp(gene name synonym)|uniprotkb:Calcium and DAG-regulated guanine nucleotide exchange factor II(gene name synonym)|uniprotkb:Ras guanyl-releasing protein(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2018)	doi:10.1093/nar/gkx1173|imex:IM-28235|pubmed:29165646	taxid:83332(myctu)|taxid:83332("Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)")	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0471"(MINT)	intact:EBI-25768286|imex:IM-28235-239	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	go:"GO:0005978"(glycogen biosynthetic process)|go:"GO:0005992"(trehalose biosynthetic process)|go:"GO:0016301"(kinase activity)|go:"GO:0046835"(carbohydrate phosphorylation)|rcsb pdb:4O7O|rcsb pdb:4O7P|go:"GO:0005524"(ATP binding)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|mint:O07177|refseq:NP_214641.1|refseq:WP_003916610.1|interpro:IPR011009(Protein kinase-like)|interpro:IPR040999	ensembl:ENSMUSG00000027347(gene)|ensembl:ENSMUST00000102534(transcript)|ensembl:ENSMUST00000178884(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001934"(positive regulation of protein phosphorylation)|go:"GO:0002437"(inflammatory response to antigenic stimulus)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0007264"(small GTPase mediated signal transduction)|go:"GO:0008270"(zinc ion binding)|go:"GO:0014066"(regulation of phosphatidylinositol 3-kinase signaling)|go:"GO:0019992"(diacylglycerol binding)|go:"GO:0030101"(natural killer cell activation)|go:"GO:0030154"(cell differentiation)|go:"GO:0031210"(phosphatidylcholine binding)|go:"GO:0032252"(secretory granule localization)|go:"GO:0032725"(positive regulation of granulocyte macrophage colony-stimulating factor production)|go:"GO:0032729"(positive regulation of interferon-gamma production)|go:"GO:0032760"(positive regulation of tumor necrosis factor production)|go:"GO:0032816"(positive regulation of natural killer cell activation)|go:"GO:0033089"(positive regulation of T cell differentiation in thymus)|go:"GO:0042098"(T cell proliferation)|go:"GO:0042100"(B cell proliferation)|go:"GO:0042110"(T cell activation)|go:"GO:0042113"(B cell activation)|go:"GO:0042802"(identical protein binding)|go:"GO:0043303"(mast cell degranulation)|go:"GO:0043406"(positive regulation of MAP kinase activity)|go:"GO:0043547"(positive regulation of GTPase activity)|go:"GO:0045954"(positive regulation of natural killer cell mediated cytotoxicity)|go:"GO:0046330"(positive regulation of JNK cascade)|go:"GO:0046579"(positive regulation of Ras protein signal transduction)|go:"GO:0047496"(vesicle transport along microtubule)|go:"GO:0070372"(regulation of ERK1 and ERK2 cascade)|go:"GO:0070374"(positive regulation of ERK1 and ERK2 cascade)|go:"GO:0090630"(activation of GTPase activity)|interpro:IPR000651(Guanine nucleotide exchange factor for Ras-like GTPases, N-terminal)|interpro:IPR001895(Guanine-nucleotide dissociation stimulator CDC25)|interpro:IPR002048(Calcium-binding EF-hand)|interpro:IPR002219(Protein kinase C, phorbol ester/diacylglycerol binding)|interpro:IPR008937(Ras guanine nucleotide exchange factor)|interpro:IPR011992(EF-Hand type)|interpro:IPR018247|interpro:IPR020454|interpro:IPR023578|interpro:IPR036964|mint:Q9Z1S3|reactome:R-MMU-1169092|reactome:R-MMU-354192|reactome:R-MMU-392517|reactome:R-MMU-5673001|go:"GO:0032825"(positive regulation of natural killer cell differentiation)|refseq:NP_035376.1	-	-	-	figure legend:ST5|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2020/07/08	2020/08/14	rogid:kpl6jZ4UbJUq/kfAlHBYpJAJV4E83332	rogid:cwPdbX3JNZhbDXCk8v0xWa/ixgY10090	rigid:iRjgwU9IsEOK8HWg5JOXGwlK0Rc	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:O69689	uniprotkb:Q9Z2B5	intact:EBI-25767781|uniprotkb:F2GFU4|uniprotkb:I6Y4D4|uniprotkb:Q7D501	intact:EBI-1226344|uniprotkb:Q9CTK8|uniprotkb:Q9CWT5	psi-mi:aspat_myctu(display_long)|uniprotkb:Rv3722c(locus name)	psi-mi:e2ak3_mouse(display_long)|uniprotkb:Eif2ak3(gene name)|psi-mi:Eif2ak3(display_short)|uniprotkb:Pek(gene name synonym)|uniprotkb:Perk(gene name synonym)|uniprotkb:PRKR-like endoplasmic reticulum kinase(gene name synonym)|uniprotkb:Pancreatic eIF2-alpha kinase(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2018)	doi:10.1093/nar/gkx1173|imex:IM-28235|pubmed:29165646	taxid:83332(myctu)|taxid:83332("Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)")	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0471"(MINT)	intact:EBI-25768211|imex:IM-28235-141	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	go:"GO:0004069"("L-aspartate:2-oxoglutarate aminotransferase activity")|go:"GO:0005576"(extracellular region)|rcsb pdb:5C6U|rcsb pdb:6U78|rcsb pdb:6U7A|mint:O69689|refseq:NP_218239.2|refseq:WP_003899653.1|interpro:IPR024551|interpro:IPR015424(Pyridoxal phosphate-dependent transferase, major region)|interpro:IPR015422(Pyridoxal phosphate-dependent transferase, major region, subdomain 2)|interpro:IPR015421(Pyridoxal phosphate-dependent transferase, major region, subdomain 1)	refseq:NP_001300847.1|mint:Q9Z2B5|dip:DIP-39494N|go:"GO:1902235"(regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway)|go:"GO:1902237"(positive regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway)|go:"GO:1903788"(positive regulation of glutathione biosynthetic process)|go:"GO:1990440"(positive regulation of transcription from RNA polymerase II promoter in response to endoplasmic reticulum stress)|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR011047(Quinonprotein alcohol dehydrogenase-like)|interpro:IPR015943(WD40/YVTN repeat-like)|rcsb pdb:3QD2|rcsb pdb:4YZY|reactome:R-MMU-381042|go:"GO:0001503"(ossification)|go:"GO:0001525"(angiogenesis)|go:"GO:0002063"(chondrocyte development)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0004694"(eukaryotic translation initiation factor 2alpha kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005829"(cytosol)|go:"GO:0006412"(translation)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0006919"(activation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0006983"(ER overload response)|go:"GO:0007029"(endoplasmic reticulum organization)|go:"GO:0007595"(lactation)|go:"GO:0009967"(positive regulation of signal transduction)|go:"GO:0010575"(positive regulation of vascular endothelial growth factor production)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0001501"(skeletal system development)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0010998"(regulation of translational initiation by eIF2 alpha phosphorylation)|go:"GO:0016021"(integral component of membrane)|go:"GO:0017148"(negative regulation of translation)|go:"GO:0018105"(peptidyl-serine phosphorylation)|go:"GO:0019217"(regulation of fatty acid metabolic process)|go:"GO:0019722"(calcium-mediated signaling)|go:"GO:0019899"(enzyme binding)|go:"GO:0019903"(protein phosphatase binding)|go:"GO:0030282"(bone mineralization)|go:"GO:0030433"(ubiquitin-dependent ERAD pathway)|go:"GO:0030968"(endoplasmic reticulum unfolded protein response)|go:"GO:0031016"(pancreas development)|go:"GO:0031018"(endocrine pancreas development)|go:"GO:0031642"(negative regulation of myelination)|go:"GO:0032055"(negative regulation of translation in response to stress)|go:"GO:0032092"(positive regulation of protein binding)|go:"GO:0032933"(SREBP signaling pathway)|go:"GO:0034198"(cellular response to amino acid starvation)|go:"GO:0034976"(response to endoplasmic reticulum stress)|go:"GO:0036492"(eiF2alpha phosphorylation in response to endoplasmic reticulum stress)|go:"GO:0036499"(PERK-mediated unfolded protein response)|go:"GO:0042149"(cellular response to glucose starvation)|go:"GO:0042802"(identical protein binding)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0044322"(endoplasmic reticulum quality control compartment)|go:"GO:0045444"(fat cell differentiation)|go:"GO:0045943"(positive regulation of transcription by RNA polymerase I)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0048009"(insulin-like growth factor receptor signaling pathway)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051879"(Hsp90 protein binding)|go:"GO:0060734"(regulation of endoplasmic reticulum stress-induced eIF2 alpha phosphorylation)|go:"GO:0070059"(intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress)|go:"GO:0070417"(cellular response to cold)|go:"GO:0071074"(eukaryotic initiation factor eIF2 binding)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:1900182"(positive regulation of protein localization to nucleus)|go:"GO:1902010"(negative regulation of translation in response to endoplasmic reticulum stress)	-	-	-	figure legend:ST5|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2020/07/08	2020/08/14	rogid:TGWnUCrIwLrRrMnna5+/w33GpgA83332	rogid:JA/YbWOU0ieAQ90kq+sS7Ul6iVI10090	rigid:S1S5eNc/yaiBxbUF8OAXUMKCbfk	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P9WHV1	uniprotkb:Q9Z2B5	intact:EBI-25768182|uniprotkb:L0TB68|uniprotkb:P65788|uniprotkb:P71921	intact:EBI-1226344|uniprotkb:Q9CTK8|uniprotkb:Q9CWT5	psi-mi:proa_myctu(display_long)|uniprotkb:proA(gene name)|psi-mi:proA(display_short)|uniprotkb:Glutamate-5-semialdehyde dehydrogenase(gene name synonym)|uniprotkb:Glutamyl-gamma-semialdehyde dehydrogenase(gene name synonym)|uniprotkb:MTCY428.20(orf name)|uniprotkb:Rv2427c(locus name)	psi-mi:e2ak3_mouse(display_long)|uniprotkb:Eif2ak3(gene name)|psi-mi:Eif2ak3(display_short)|uniprotkb:Pek(gene name synonym)|uniprotkb:Perk(gene name synonym)|uniprotkb:PRKR-like endoplasmic reticulum kinase(gene name synonym)|uniprotkb:Pancreatic eIF2-alpha kinase(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2018)	doi:10.1093/nar/gkx1173|imex:IM-28235|pubmed:29165646	taxid:83332(myctu)|taxid:83332("Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)")	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0471"(MINT)	intact:EBI-25768205|imex:IM-28235-237	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	go:"GO:0004350"(glutamate-5-semialdehyde dehydrogenase activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0050661"(NADP binding)|go:"GO:0055129"(L-proline biosynthetic process)|go:"GO:0005829"(cytosol)|mint:P9WHV1|refseq:NP_216943.1|refseq:WP_003412516.1|interpro:IPR016161(Aldehyde/histidinol dehydrogenase)|interpro:IPR016163(Aldehyde dehydrogenase, C-terminal)|interpro:IPR016162(Aldehyde dehydrogenase, N-terminal)|interpro:IPR015590(Aldehyde dehydrogenase)|interpro:IPR020593|interpro:IPR012134(Glutamate-5-semialdehyde dehydrogenase)|interpro:IPR000965(Gamma-glutamyl phosphate reductase GPR)	refseq:NP_001300847.1|mint:Q9Z2B5|dip:DIP-39494N|go:"GO:1902235"(regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway)|go:"GO:1902237"(positive regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway)|go:"GO:1903788"(positive regulation of glutathione biosynthetic process)|go:"GO:1990440"(positive regulation of transcription from RNA polymerase II promoter in response to endoplasmic reticulum stress)|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR011047(Quinonprotein alcohol dehydrogenase-like)|interpro:IPR015943(WD40/YVTN repeat-like)|rcsb pdb:3QD2|rcsb pdb:4YZY|reactome:R-MMU-381042|go:"GO:0001503"(ossification)|go:"GO:0001525"(angiogenesis)|go:"GO:0002063"(chondrocyte development)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0004694"(eukaryotic translation initiation factor 2alpha kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005829"(cytosol)|go:"GO:0006412"(translation)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0006919"(activation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0006983"(ER overload response)|go:"GO:0007029"(endoplasmic reticulum organization)|go:"GO:0007595"(lactation)|go:"GO:0009967"(positive regulation of signal transduction)|go:"GO:0010575"(positive regulation of vascular endothelial growth factor production)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0001501"(skeletal system development)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0010998"(regulation of translational initiation by eIF2 alpha phosphorylation)|go:"GO:0016021"(integral component of membrane)|go:"GO:0017148"(negative regulation of translation)|go:"GO:0018105"(peptidyl-serine phosphorylation)|go:"GO:0019217"(regulation of fatty acid metabolic process)|go:"GO:0019722"(calcium-mediated signaling)|go:"GO:0019899"(enzyme binding)|go:"GO:0019903"(protein phosphatase binding)|go:"GO:0030282"(bone mineralization)|go:"GO:0030433"(ubiquitin-dependent ERAD pathway)|go:"GO:0030968"(endoplasmic reticulum unfolded protein response)|go:"GO:0031016"(pancreas development)|go:"GO:0031018"(endocrine pancreas development)|go:"GO:0031642"(negative regulation of myelination)|go:"GO:0032055"(negative regulation of translation in response to stress)|go:"GO:0032092"(positive regulation of protein binding)|go:"GO:0032933"(SREBP signaling pathway)|go:"GO:0034198"(cellular response to amino acid starvation)|go:"GO:0034976"(response to endoplasmic reticulum stress)|go:"GO:0036492"(eiF2alpha phosphorylation in response to endoplasmic reticulum stress)|go:"GO:0036499"(PERK-mediated unfolded protein response)|go:"GO:0042149"(cellular response to glucose starvation)|go:"GO:0042802"(identical protein binding)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0044322"(endoplasmic reticulum quality control compartment)|go:"GO:0045444"(fat cell differentiation)|go:"GO:0045943"(positive regulation of transcription by RNA polymerase I)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0048009"(insulin-like growth factor receptor signaling pathway)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051879"(Hsp90 protein binding)|go:"GO:0060734"(regulation of endoplasmic reticulum stress-induced eIF2 alpha phosphorylation)|go:"GO:0070059"(intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress)|go:"GO:0070417"(cellular response to cold)|go:"GO:0071074"(eukaryotic initiation factor eIF2 binding)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:1900182"(positive regulation of protein localization to nucleus)|go:"GO:1902010"(negative regulation of translation in response to endoplasmic reticulum stress)	-	-	-	figure legend:ST5|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2020/07/08	2020/08/14	rogid:fzCkUX2wrGj0ZK0LOaeT+UNWpwI83332	rogid:JA/YbWOU0ieAQ90kq+sS7Ul6iVI10090	rigid:9R4F40gojYqQv2NHNSh4dQnAw7I	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:O53319	uniprotkb:Q9Z2B5	intact:EBI-25767766|uniprotkb:I6X6K2|uniprotkb:L0TEH7	intact:EBI-1226344|uniprotkb:Q9CTK8|uniprotkb:Q9CWT5	psi-mi:o53319_myctu(display_long)|uniprotkb:Rv3169(locus name)	psi-mi:e2ak3_mouse(display_long)|uniprotkb:Eif2ak3(gene name)|psi-mi:Eif2ak3(display_short)|uniprotkb:Pek(gene name synonym)|uniprotkb:Perk(gene name synonym)|uniprotkb:PRKR-like endoplasmic reticulum kinase(gene name synonym)|uniprotkb:Pancreatic eIF2-alpha kinase(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2018)	doi:10.1093/nar/gkx1173|imex:IM-28235|pubmed:29165646	taxid:83332(myctu)|taxid:83332("Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)")	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0471"(MINT)	intact:EBI-25768176|imex:IM-28235-273	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	go:"GO:0005886"(plasma membrane)|mint:O53319|refseq:NP_217685.1|refseq:WP_003416605.1	refseq:NP_001300847.1|mint:Q9Z2B5|dip:DIP-39494N|go:"GO:1902235"(regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway)|go:"GO:1902237"(positive regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway)|go:"GO:1903788"(positive regulation of glutathione biosynthetic process)|go:"GO:1990440"(positive regulation of transcription from RNA polymerase II promoter in response to endoplasmic reticulum stress)|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR011047(Quinonprotein alcohol dehydrogenase-like)|interpro:IPR015943(WD40/YVTN repeat-like)|rcsb pdb:3QD2|rcsb pdb:4YZY|reactome:R-MMU-381042|go:"GO:0001503"(ossification)|go:"GO:0001525"(angiogenesis)|go:"GO:0002063"(chondrocyte development)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0004694"(eukaryotic translation initiation factor 2alpha kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005829"(cytosol)|go:"GO:0006412"(translation)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0006919"(activation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0006983"(ER overload response)|go:"GO:0007029"(endoplasmic reticulum organization)|go:"GO:0007595"(lactation)|go:"GO:0009967"(positive regulation of signal transduction)|go:"GO:0010575"(positive regulation of vascular endothelial growth factor production)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0001501"(skeletal system development)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0010998"(regulation of translational initiation by eIF2 alpha phosphorylation)|go:"GO:0016021"(integral component of membrane)|go:"GO:0017148"(negative regulation of translation)|go:"GO:0018105"(peptidyl-serine phosphorylation)|go:"GO:0019217"(regulation of fatty acid metabolic process)|go:"GO:0019722"(calcium-mediated signaling)|go:"GO:0019899"(enzyme binding)|go:"GO:0019903"(protein phosphatase binding)|go:"GO:0030282"(bone mineralization)|go:"GO:0030433"(ubiquitin-dependent ERAD pathway)|go:"GO:0030968"(endoplasmic reticulum unfolded protein response)|go:"GO:0031016"(pancreas development)|go:"GO:0031018"(endocrine pancreas development)|go:"GO:0031642"(negative regulation of myelination)|go:"GO:0032055"(negative regulation of translation in response to stress)|go:"GO:0032092"(positive regulation of protein binding)|go:"GO:0032933"(SREBP signaling pathway)|go:"GO:0034198"(cellular response to amino acid starvation)|go:"GO:0034976"(response to endoplasmic reticulum stress)|go:"GO:0036492"(eiF2alpha phosphorylation in response to endoplasmic reticulum stress)|go:"GO:0036499"(PERK-mediated unfolded protein response)|go:"GO:0042149"(cellular response to glucose starvation)|go:"GO:0042802"(identical protein binding)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0044322"(endoplasmic reticulum quality control compartment)|go:"GO:0045444"(fat cell differentiation)|go:"GO:0045943"(positive regulation of transcription by RNA polymerase I)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0048009"(insulin-like growth factor receptor signaling pathway)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051879"(Hsp90 protein binding)|go:"GO:0060734"(regulation of endoplasmic reticulum stress-induced eIF2 alpha phosphorylation)|go:"GO:0070059"(intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress)|go:"GO:0070417"(cellular response to cold)|go:"GO:0071074"(eukaryotic initiation factor eIF2 binding)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:1900182"(positive regulation of protein localization to nucleus)|go:"GO:1902010"(negative regulation of translation in response to endoplasmic reticulum stress)	-	-	-	figure legend:ST5|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2020/07/08	2020/08/14	rogid:Gd1O5B5qTAQflXzn9MR+6fgqvDs83332	rogid:JA/YbWOU0ieAQ90kq+sS7Ul6iVI10090	rigid:c98DCDwoWYmh4uS94O60DfLeww4	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:O50440	uniprotkb:Q9Z2B5	intact:EBI-25767742|uniprotkb:I6XXB2|uniprotkb:L0T7J5	intact:EBI-1226344|uniprotkb:Q9CTK8|uniprotkb:Q9CWT5	psi-mi:chp2_myctu(display_long)|uniprotkb:chp2(gene name)|psi-mi:chp2(display_short)|uniprotkb:LH57_06500(orf name)|uniprotkb:P425_01234(orf name)|uniprotkb:Rv1184c(locus name)|uniprotkb:RVBD_1184c(locus name)	psi-mi:e2ak3_mouse(display_long)|uniprotkb:Eif2ak3(gene name)|psi-mi:Eif2ak3(display_short)|uniprotkb:Pek(gene name synonym)|uniprotkb:Perk(gene name synonym)|uniprotkb:PRKR-like endoplasmic reticulum kinase(gene name synonym)|uniprotkb:Pancreatic eIF2-alpha kinase(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2018)	doi:10.1093/nar/gkx1173|imex:IM-28235|pubmed:29165646	taxid:83332(myctu)|taxid:83332("Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)")	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0471"(MINT)	intact:EBI-25768170|imex:IM-28235-319	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	go:"GO:0005886"(plasma membrane)|go:"GO:0006629"(lipid metabolic process)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016746"(acyltransferase activity)|go:"GO:0005618"(cell wall)|mint:O50440|refseq:NP_215700.1|refseq:WP_003406195.1|interpro:IPR013228(PE-PPE, C-terminal)	refseq:NP_001300847.1|mint:Q9Z2B5|dip:DIP-39494N|go:"GO:1902235"(regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway)|go:"GO:1902237"(positive regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway)|go:"GO:1903788"(positive regulation of glutathione biosynthetic process)|go:"GO:1990440"(positive regulation of transcription from RNA polymerase II promoter in response to endoplasmic reticulum stress)|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR011047(Quinonprotein alcohol dehydrogenase-like)|interpro:IPR015943(WD40/YVTN repeat-like)|rcsb pdb:3QD2|rcsb pdb:4YZY|reactome:R-MMU-381042|go:"GO:0001503"(ossification)|go:"GO:0001525"(angiogenesis)|go:"GO:0002063"(chondrocyte development)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0004694"(eukaryotic translation initiation factor 2alpha kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005829"(cytosol)|go:"GO:0006412"(translation)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0006919"(activation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0006983"(ER overload response)|go:"GO:0007029"(endoplasmic reticulum organization)|go:"GO:0007595"(lactation)|go:"GO:0009967"(positive regulation of signal transduction)|go:"GO:0010575"(positive regulation of vascular endothelial growth factor production)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0001501"(skeletal system development)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0010998"(regulation of translational initiation by eIF2 alpha phosphorylation)|go:"GO:0016021"(integral component of membrane)|go:"GO:0017148"(negative regulation of translation)|go:"GO:0018105"(peptidyl-serine phosphorylation)|go:"GO:0019217"(regulation of fatty acid metabolic process)|go:"GO:0019722"(calcium-mediated signaling)|go:"GO:0019899"(enzyme binding)|go:"GO:0019903"(protein phosphatase binding)|go:"GO:0030282"(bone mineralization)|go:"GO:0030433"(ubiquitin-dependent ERAD pathway)|go:"GO:0030968"(endoplasmic reticulum unfolded protein response)|go:"GO:0031016"(pancreas development)|go:"GO:0031018"(endocrine pancreas development)|go:"GO:0031642"(negative regulation of myelination)|go:"GO:0032055"(negative regulation of translation in response to stress)|go:"GO:0032092"(positive regulation of protein binding)|go:"GO:0032933"(SREBP signaling pathway)|go:"GO:0034198"(cellular response to amino acid starvation)|go:"GO:0034976"(response to endoplasmic reticulum stress)|go:"GO:0036492"(eiF2alpha phosphorylation in response to endoplasmic reticulum stress)|go:"GO:0036499"(PERK-mediated unfolded protein response)|go:"GO:0042149"(cellular response to glucose starvation)|go:"GO:0042802"(identical protein binding)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0044322"(endoplasmic reticulum quality control compartment)|go:"GO:0045444"(fat cell differentiation)|go:"GO:0045943"(positive regulation of transcription by RNA polymerase I)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0048009"(insulin-like growth factor receptor signaling pathway)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051879"(Hsp90 protein binding)|go:"GO:0060734"(regulation of endoplasmic reticulum stress-induced eIF2 alpha phosphorylation)|go:"GO:0070059"(intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress)|go:"GO:0070417"(cellular response to cold)|go:"GO:0071074"(eukaryotic initiation factor eIF2 binding)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:1900182"(positive regulation of protein localization to nucleus)|go:"GO:1902010"(negative regulation of translation in response to endoplasmic reticulum stress)	-	-	-	figure legend:ST5|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2020/07/08	2020/08/14	rogid:IXzYfb7UxFgqBXPZ6NZHLy3hdTc83332	rogid:JA/YbWOU0ieAQ90kq+sS7Ul6iVI10090	rigid:29o24gL9p25arUN+pZmSF39sg24	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:O53850	uniprotkb:Q9Z2B5	intact:EBI-25768148|uniprotkb:F2GJ15|uniprotkb:I6XWE0	intact:EBI-1226344|uniprotkb:Q9CTK8|uniprotkb:Q9CWT5	psi-mi:o53850_myctu(display_long)|uniprotkb:lpqR(gene name)|psi-mi:lpqR(display_short)|uniprotkb:Rv0838(locus name)	psi-mi:e2ak3_mouse(display_long)|uniprotkb:Eif2ak3(gene name)|psi-mi:Eif2ak3(display_short)|uniprotkb:Pek(gene name synonym)|uniprotkb:Perk(gene name synonym)|uniprotkb:PRKR-like endoplasmic reticulum kinase(gene name synonym)|uniprotkb:Pancreatic eIF2-alpha kinase(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2018)	doi:10.1093/nar/gkx1173|imex:IM-28235|pubmed:29165646	taxid:83332(myctu)|taxid:83332("Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)")	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0471"(MINT)	intact:EBI-25768164|imex:IM-28235-187	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	go:"GO:0005576"(extracellular region)|go:"GO:0008237"(metallopeptidase activity)|go:"GO:0008270"(zinc ion binding)|go:"GO:0016805"(dipeptidase activity)|go:"GO:0071555"(cell wall organization)|mint:O53850|refseq:NP_215353.1|refseq:WP_003898609.1|interpro:IPR000755(Peptidase M15D, vanX D-ala-D-ala dipeptidase)|interpro:IPR009045(Hedgehog/DD-peptidase, zinc-binding motif)	refseq:NP_001300847.1|mint:Q9Z2B5|dip:DIP-39494N|go:"GO:1902235"(regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway)|go:"GO:1902237"(positive regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway)|go:"GO:1903788"(positive regulation of glutathione biosynthetic process)|go:"GO:1990440"(positive regulation of transcription from RNA polymerase II promoter in response to endoplasmic reticulum stress)|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR011047(Quinonprotein alcohol dehydrogenase-like)|interpro:IPR015943(WD40/YVTN repeat-like)|rcsb pdb:3QD2|rcsb pdb:4YZY|reactome:R-MMU-381042|go:"GO:0001503"(ossification)|go:"GO:0001525"(angiogenesis)|go:"GO:0002063"(chondrocyte development)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0004694"(eukaryotic translation initiation factor 2alpha kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005829"(cytosol)|go:"GO:0006412"(translation)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0006919"(activation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0006983"(ER overload response)|go:"GO:0007029"(endoplasmic reticulum organization)|go:"GO:0007595"(lactation)|go:"GO:0009967"(positive regulation of signal transduction)|go:"GO:0010575"(positive regulation of vascular endothelial growth factor production)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0001501"(skeletal system development)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0010998"(regulation of translational initiation by eIF2 alpha phosphorylation)|go:"GO:0016021"(integral component of membrane)|go:"GO:0017148"(negative regulation of translation)|go:"GO:0018105"(peptidyl-serine phosphorylation)|go:"GO:0019217"(regulation of fatty acid metabolic process)|go:"GO:0019722"(calcium-mediated signaling)|go:"GO:0019899"(enzyme binding)|go:"GO:0019903"(protein phosphatase binding)|go:"GO:0030282"(bone mineralization)|go:"GO:0030433"(ubiquitin-dependent ERAD pathway)|go:"GO:0030968"(endoplasmic reticulum unfolded protein response)|go:"GO:0031016"(pancreas development)|go:"GO:0031018"(endocrine pancreas development)|go:"GO:0031642"(negative regulation of myelination)|go:"GO:0032055"(negative regulation of translation in response to stress)|go:"GO:0032092"(positive regulation of protein binding)|go:"GO:0032933"(SREBP signaling pathway)|go:"GO:0034198"(cellular response to amino acid starvation)|go:"GO:0034976"(response to endoplasmic reticulum stress)|go:"GO:0036492"(eiF2alpha phosphorylation in response to endoplasmic reticulum stress)|go:"GO:0036499"(PERK-mediated unfolded protein response)|go:"GO:0042149"(cellular response to glucose starvation)|go:"GO:0042802"(identical protein binding)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0044322"(endoplasmic reticulum quality control compartment)|go:"GO:0045444"(fat cell differentiation)|go:"GO:0045943"(positive regulation of transcription by RNA polymerase I)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0048009"(insulin-like growth factor receptor signaling pathway)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051879"(Hsp90 protein binding)|go:"GO:0060734"(regulation of endoplasmic reticulum stress-induced eIF2 alpha phosphorylation)|go:"GO:0070059"(intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress)|go:"GO:0070417"(cellular response to cold)|go:"GO:0071074"(eukaryotic initiation factor eIF2 binding)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:1900182"(positive regulation of protein localization to nucleus)|go:"GO:1902010"(negative regulation of translation in response to endoplasmic reticulum stress)	-	-	-	figure legend:ST5|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2020/07/08	2020/08/14	rogid:40KIrYcfAW5IBFq1Hx5FLVOcLf483332	rogid:JA/YbWOU0ieAQ90kq+sS7Ul6iVI10090	rigid:7e3b3VWLnaPtvFC65s9xfAJuWgE	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:I6Y946	uniprotkb:Q9Z2B5	intact:EBI-25767727	intact:EBI-1226344|uniprotkb:Q9CTK8|uniprotkb:Q9CWT5	psi-mi:i6y946_myctu(display_long)|uniprotkb:Rv0925c(locus name)	psi-mi:e2ak3_mouse(display_long)|uniprotkb:Eif2ak3(gene name)|psi-mi:Eif2ak3(display_short)|uniprotkb:Pek(gene name synonym)|uniprotkb:Perk(gene name synonym)|uniprotkb:PRKR-like endoplasmic reticulum kinase(gene name synonym)|uniprotkb:Pancreatic eIF2-alpha kinase(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2018)	doi:10.1093/nar/gkx1173|imex:IM-28235|pubmed:29165646	taxid:83332(myctu)|taxid:83332("Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)")	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0471"(MINT)	intact:EBI-25768142|imex:IM-28235-63	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	go:"GO:0016491"(oxidoreductase activity)|mint:I6Y946|refseq:NP_215440.1|refseq:WP_003404764.1|interpro:IPR029039|interpro:IPR005025(NADPH-dependent FMN reductase)	refseq:NP_001300847.1|mint:Q9Z2B5|dip:DIP-39494N|go:"GO:1902235"(regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway)|go:"GO:1902237"(positive regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway)|go:"GO:1903788"(positive regulation of glutathione biosynthetic process)|go:"GO:1990440"(positive regulation of transcription from RNA polymerase II promoter in response to endoplasmic reticulum stress)|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR011047(Quinonprotein alcohol dehydrogenase-like)|interpro:IPR015943(WD40/YVTN repeat-like)|rcsb pdb:3QD2|rcsb pdb:4YZY|reactome:R-MMU-381042|go:"GO:0001503"(ossification)|go:"GO:0001525"(angiogenesis)|go:"GO:0002063"(chondrocyte development)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0004694"(eukaryotic translation initiation factor 2alpha kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005829"(cytosol)|go:"GO:0006412"(translation)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0006919"(activation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0006983"(ER overload response)|go:"GO:0007029"(endoplasmic reticulum organization)|go:"GO:0007595"(lactation)|go:"GO:0009967"(positive regulation of signal transduction)|go:"GO:0010575"(positive regulation of vascular endothelial growth factor production)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0001501"(skeletal system development)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0010998"(regulation of translational initiation by eIF2 alpha phosphorylation)|go:"GO:0016021"(integral component of membrane)|go:"GO:0017148"(negative regulation of translation)|go:"GO:0018105"(peptidyl-serine phosphorylation)|go:"GO:0019217"(regulation of fatty acid metabolic process)|go:"GO:0019722"(calcium-mediated signaling)|go:"GO:0019899"(enzyme binding)|go:"GO:0019903"(protein phosphatase binding)|go:"GO:0030282"(bone mineralization)|go:"GO:0030433"(ubiquitin-dependent ERAD pathway)|go:"GO:0030968"(endoplasmic reticulum unfolded protein response)|go:"GO:0031016"(pancreas development)|go:"GO:0031018"(endocrine pancreas development)|go:"GO:0031642"(negative regulation of myelination)|go:"GO:0032055"(negative regulation of translation in response to stress)|go:"GO:0032092"(positive regulation of protein binding)|go:"GO:0032933"(SREBP signaling pathway)|go:"GO:0034198"(cellular response to amino acid starvation)|go:"GO:0034976"(response to endoplasmic reticulum stress)|go:"GO:0036492"(eiF2alpha phosphorylation in response to endoplasmic reticulum stress)|go:"GO:0036499"(PERK-mediated unfolded protein response)|go:"GO:0042149"(cellular response to glucose starvation)|go:"GO:0042802"(identical protein binding)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0044322"(endoplasmic reticulum quality control compartment)|go:"GO:0045444"(fat cell differentiation)|go:"GO:0045943"(positive regulation of transcription by RNA polymerase I)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0048009"(insulin-like growth factor receptor signaling pathway)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051879"(Hsp90 protein binding)|go:"GO:0060734"(regulation of endoplasmic reticulum stress-induced eIF2 alpha phosphorylation)|go:"GO:0070059"(intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress)|go:"GO:0070417"(cellular response to cold)|go:"GO:0071074"(eukaryotic initiation factor eIF2 binding)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:1900182"(positive regulation of protein localization to nucleus)|go:"GO:1902010"(negative regulation of translation in response to endoplasmic reticulum stress)	-	-	-	figure legend:ST5|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2020/07/08	2020/08/14	rogid:JOW06LtizimdrjJdMmMnM9ru8n083332	rogid:JA/YbWOU0ieAQ90kq+sS7Ul6iVI10090	rigid:cse8GP7sKEiZhgLruTFyw7eU/7E	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:O07422	uniprotkb:Q9Z2B5	intact:EBI-25767563|uniprotkb:F2GLX6|uniprotkb:I6Y302|uniprotkb:Q7DAB9	intact:EBI-1226344|uniprotkb:Q9CTK8|uniprotkb:Q9CWT5	psi-mi:o07422_myctu(display_long)|uniprotkb:Rv0178(locus name)	psi-mi:e2ak3_mouse(display_long)|uniprotkb:Eif2ak3(gene name)|psi-mi:Eif2ak3(display_short)|uniprotkb:Pek(gene name synonym)|uniprotkb:Perk(gene name synonym)|uniprotkb:PRKR-like endoplasmic reticulum kinase(gene name synonym)|uniprotkb:Pancreatic eIF2-alpha kinase(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2018)	doi:10.1093/nar/gkx1173|imex:IM-28235|pubmed:29165646	taxid:83332(myctu)|taxid:83332("Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)")	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0471"(MINT)	intact:EBI-25768136|imex:IM-28235-61	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	go:"GO:0005576"(extracellular region)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0051701"(biological process involved in interaction with host)|mint:O07422|refseq:NP_214692.1|refseq:WP_003899844.1	refseq:NP_001300847.1|mint:Q9Z2B5|dip:DIP-39494N|go:"GO:1902235"(regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway)|go:"GO:1902237"(positive regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway)|go:"GO:1903788"(positive regulation of glutathione biosynthetic process)|go:"GO:1990440"(positive regulation of transcription from RNA polymerase II promoter in response to endoplasmic reticulum stress)|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR011047(Quinonprotein alcohol dehydrogenase-like)|interpro:IPR015943(WD40/YVTN repeat-like)|rcsb pdb:3QD2|rcsb pdb:4YZY|reactome:R-MMU-381042|go:"GO:0001503"(ossification)|go:"GO:0001525"(angiogenesis)|go:"GO:0002063"(chondrocyte development)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0004694"(eukaryotic translation initiation factor 2alpha kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005829"(cytosol)|go:"GO:0006412"(translation)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0006919"(activation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0006983"(ER overload response)|go:"GO:0007029"(endoplasmic reticulum organization)|go:"GO:0007595"(lactation)|go:"GO:0009967"(positive regulation of signal transduction)|go:"GO:0010575"(positive regulation of vascular endothelial growth factor production)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0001501"(skeletal system development)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0010998"(regulation of translational initiation by eIF2 alpha phosphorylation)|go:"GO:0016021"(integral component of membrane)|go:"GO:0017148"(negative regulation of translation)|go:"GO:0018105"(peptidyl-serine phosphorylation)|go:"GO:0019217"(regulation of fatty acid metabolic process)|go:"GO:0019722"(calcium-mediated signaling)|go:"GO:0019899"(enzyme binding)|go:"GO:0019903"(protein phosphatase binding)|go:"GO:0030282"(bone mineralization)|go:"GO:0030433"(ubiquitin-dependent ERAD pathway)|go:"GO:0030968"(endoplasmic reticulum unfolded protein response)|go:"GO:0031016"(pancreas development)|go:"GO:0031018"(endocrine pancreas development)|go:"GO:0031642"(negative regulation of myelination)|go:"GO:0032055"(negative regulation of translation in response to stress)|go:"GO:0032092"(positive regulation of protein binding)|go:"GO:0032933"(SREBP signaling pathway)|go:"GO:0034198"(cellular response to amino acid starvation)|go:"GO:0034976"(response to endoplasmic reticulum stress)|go:"GO:0036492"(eiF2alpha phosphorylation in response to endoplasmic reticulum stress)|go:"GO:0036499"(PERK-mediated unfolded protein response)|go:"GO:0042149"(cellular response to glucose starvation)|go:"GO:0042802"(identical protein binding)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0044322"(endoplasmic reticulum quality control compartment)|go:"GO:0045444"(fat cell differentiation)|go:"GO:0045943"(positive regulation of transcription by RNA polymerase I)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0048009"(insulin-like growth factor receptor signaling pathway)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051879"(Hsp90 protein binding)|go:"GO:0060734"(regulation of endoplasmic reticulum stress-induced eIF2 alpha phosphorylation)|go:"GO:0070059"(intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress)|go:"GO:0070417"(cellular response to cold)|go:"GO:0071074"(eukaryotic initiation factor eIF2 binding)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:1900182"(positive regulation of protein localization to nucleus)|go:"GO:1902010"(negative regulation of translation in response to endoplasmic reticulum stress)	-	-	-	figure legend:ST5|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2020/07/08	2020/08/14	rogid:lGOg72Osvz8819m674JzGUcHEj483332	rogid:JA/YbWOU0ieAQ90kq+sS7Ul6iVI10090	rigid:Z6eOkQC5ZeOCVCNqqzBPWugnVIo	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P9WJB9	uniprotkb:Q9Z2B5	intact:EBI-25767670|uniprotkb:L0TE21|uniprotkb:O69744|uniprotkb:Q7D4P0	intact:EBI-1226344|uniprotkb:Q9CTK8|uniprotkb:Q9CWT5	psi-mi:espl_myctu(display_long)|uniprotkb:espL(gene name)|psi-mi:espL(display_short)|uniprotkb:Rv3880c(locus name)	psi-mi:e2ak3_mouse(display_long)|uniprotkb:Eif2ak3(gene name)|psi-mi:Eif2ak3(display_short)|uniprotkb:Pek(gene name synonym)|uniprotkb:Perk(gene name synonym)|uniprotkb:PRKR-like endoplasmic reticulum kinase(gene name synonym)|uniprotkb:Pancreatic eIF2-alpha kinase(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2018)	doi:10.1093/nar/gkx1173|imex:IM-28235|pubmed:29165646	taxid:83332(myctu)|taxid:83332("Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)")	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0471"(MINT)	intact:EBI-25768130|imex:IM-28235-89	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	go:"GO:0003677"(DNA binding)|go:"GO:0005618"(cell wall)|go:"GO:0005886"(plasma membrane)|go:"GO:0052170"(suppression by symbiont of host innate immune response)|mint:P9WJB9|refseq:NP_218397.1|refseq:WP_003399988.1|interpro:IPR036894|interpro:IPR004401(Conserved hypothetical protein CHP00103)	refseq:NP_001300847.1|mint:Q9Z2B5|dip:DIP-39494N|go:"GO:1902235"(regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway)|go:"GO:1902237"(positive regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway)|go:"GO:1903788"(positive regulation of glutathione biosynthetic process)|go:"GO:1990440"(positive regulation of transcription from RNA polymerase II promoter in response to endoplasmic reticulum stress)|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR011047(Quinonprotein alcohol dehydrogenase-like)|interpro:IPR015943(WD40/YVTN repeat-like)|rcsb pdb:3QD2|rcsb pdb:4YZY|reactome:R-MMU-381042|go:"GO:0001503"(ossification)|go:"GO:0001525"(angiogenesis)|go:"GO:0002063"(chondrocyte development)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0004694"(eukaryotic translation initiation factor 2alpha kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005829"(cytosol)|go:"GO:0006412"(translation)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0006919"(activation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0006983"(ER overload response)|go:"GO:0007029"(endoplasmic reticulum organization)|go:"GO:0007595"(lactation)|go:"GO:0009967"(positive regulation of signal transduction)|go:"GO:0010575"(positive regulation of vascular endothelial growth factor production)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0001501"(skeletal system development)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0010998"(regulation of translational initiation by eIF2 alpha phosphorylation)|go:"GO:0016021"(integral component of membrane)|go:"GO:0017148"(negative regulation of translation)|go:"GO:0018105"(peptidyl-serine phosphorylation)|go:"GO:0019217"(regulation of fatty acid metabolic process)|go:"GO:0019722"(calcium-mediated signaling)|go:"GO:0019899"(enzyme binding)|go:"GO:0019903"(protein phosphatase binding)|go:"GO:0030282"(bone mineralization)|go:"GO:0030433"(ubiquitin-dependent ERAD pathway)|go:"GO:0030968"(endoplasmic reticulum unfolded protein response)|go:"GO:0031016"(pancreas development)|go:"GO:0031018"(endocrine pancreas development)|go:"GO:0031642"(negative regulation of myelination)|go:"GO:0032055"(negative regulation of translation in response to stress)|go:"GO:0032092"(positive regulation of protein binding)|go:"GO:0032933"(SREBP signaling pathway)|go:"GO:0034198"(cellular response to amino acid starvation)|go:"GO:0034976"(response to endoplasmic reticulum stress)|go:"GO:0036492"(eiF2alpha phosphorylation in response to endoplasmic reticulum stress)|go:"GO:0036499"(PERK-mediated unfolded protein response)|go:"GO:0042149"(cellular response to glucose starvation)|go:"GO:0042802"(identical protein binding)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0044322"(endoplasmic reticulum quality control compartment)|go:"GO:0045444"(fat cell differentiation)|go:"GO:0045943"(positive regulation of transcription by RNA polymerase I)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0048009"(insulin-like growth factor receptor signaling pathway)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051879"(Hsp90 protein binding)|go:"GO:0060734"(regulation of endoplasmic reticulum stress-induced eIF2 alpha phosphorylation)|go:"GO:0070059"(intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress)|go:"GO:0070417"(cellular response to cold)|go:"GO:0071074"(eukaryotic initiation factor eIF2 binding)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:1900182"(positive regulation of protein localization to nucleus)|go:"GO:1902010"(negative regulation of translation in response to endoplasmic reticulum stress)	-	-	-	figure legend:ST5|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2020/07/08	2020/08/14	rogid:BspTx2RZuhJaQ319NBDIyOreqfE83332	rogid:JA/YbWOU0ieAQ90kq+sS7Ul6iVI10090	rigid:rrrxnPOS/g8DWjA5IEpE8d0LVbo	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q9Z2B5	uniprotkb:P9WNI7	intact:EBI-1226344|uniprotkb:Q9CTK8|uniprotkb:Q9CWT5	intact:EBI-9027314|uniprotkb:P95242|uniprotkb:L0T9C9	psi-mi:e2ak3_mouse(display_long)|uniprotkb:Eif2ak3(gene name)|psi-mi:Eif2ak3(display_short)|uniprotkb:Pek(gene name synonym)|uniprotkb:Perk(gene name synonym)|uniprotkb:PRKR-like endoplasmic reticulum kinase(gene name synonym)|uniprotkb:Pancreatic eIF2-alpha kinase(gene name synonym)	psi-mi:esxo_myctu(display_long)|uniprotkb:esxO(gene name)|psi-mi:esxO(display_short)|uniprotkb:MTCY98.15c(orf name)|uniprotkb:Rv2346c(locus name)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2018)	doi:10.1093/nar/gkx1173|imex:IM-28235|pubmed:29165646	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:83332(myctu)|taxid:83332("Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)")	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0471"(MINT)	intact:EBI-25768124|imex:IM-28235-139	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001300847.1|mint:Q9Z2B5|dip:DIP-39494N|go:"GO:1902235"(regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway)|go:"GO:1902237"(positive regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway)|go:"GO:1903788"(positive regulation of glutathione biosynthetic process)|go:"GO:1990440"(positive regulation of transcription from RNA polymerase II promoter in response to endoplasmic reticulum stress)|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR011047(Quinonprotein alcohol dehydrogenase-like)|interpro:IPR015943(WD40/YVTN repeat-like)|rcsb pdb:3QD2|rcsb pdb:4YZY|reactome:R-MMU-381042|go:"GO:0001503"(ossification)|go:"GO:0001525"(angiogenesis)|go:"GO:0002063"(chondrocyte development)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0004694"(eukaryotic translation initiation factor 2alpha kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005829"(cytosol)|go:"GO:0006412"(translation)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0006919"(activation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0006983"(ER overload response)|go:"GO:0007029"(endoplasmic reticulum organization)|go:"GO:0007595"(lactation)|go:"GO:0009967"(positive regulation of signal transduction)|go:"GO:0010575"(positive regulation of vascular endothelial growth factor production)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0001501"(skeletal system development)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0010998"(regulation of translational initiation by eIF2 alpha phosphorylation)|go:"GO:0016021"(integral component of membrane)|go:"GO:0017148"(negative regulation of translation)|go:"GO:0018105"(peptidyl-serine phosphorylation)|go:"GO:0019217"(regulation of fatty acid metabolic process)|go:"GO:0019722"(calcium-mediated signaling)|go:"GO:0019899"(enzyme binding)|go:"GO:0019903"(protein phosphatase binding)|go:"GO:0030282"(bone mineralization)|go:"GO:0030433"(ubiquitin-dependent ERAD pathway)|go:"GO:0030968"(endoplasmic reticulum unfolded protein response)|go:"GO:0031016"(pancreas development)|go:"GO:0031018"(endocrine pancreas development)|go:"GO:0031642"(negative regulation of myelination)|go:"GO:0032055"(negative regulation of translation in response to stress)|go:"GO:0032092"(positive regulation of protein binding)|go:"GO:0032933"(SREBP signaling pathway)|go:"GO:0034198"(cellular response to amino acid starvation)|go:"GO:0034976"(response to endoplasmic reticulum stress)|go:"GO:0036492"(eiF2alpha phosphorylation in response to endoplasmic reticulum stress)|go:"GO:0036499"(PERK-mediated unfolded protein response)|go:"GO:0042149"(cellular response to glucose starvation)|go:"GO:0042802"(identical protein binding)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0044322"(endoplasmic reticulum quality control compartment)|go:"GO:0045444"(fat cell differentiation)|go:"GO:0045943"(positive regulation of transcription by RNA polymerase I)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0048009"(insulin-like growth factor receptor signaling pathway)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051879"(Hsp90 protein binding)|go:"GO:0060734"(regulation of endoplasmic reticulum stress-induced eIF2 alpha phosphorylation)|go:"GO:0070059"(intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress)|go:"GO:0070417"(cellular response to cold)|go:"GO:0071074"(eukaryotic initiation factor eIF2 binding)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:1900182"(positive regulation of protein localization to nucleus)|go:"GO:1902010"(negative regulation of translation in response to endoplasmic reticulum stress)	mint:P9WNI7|interpro:IPR036689|interpro:IPR009416(Protein of unknown function DUF1066)|interpro:IPR010310(Protein of unknown function DUF909)|refseq:NP_216862.1|refseq:WP_003899283.1|go:"GO:0005576"(extracellular region)|go:"GO:0005618"(cell wall)|go:"GO:0005886"(plasma membrane)|rcsb pdb:3OGI|rcsb pdb:4GZR	-	-	-	figure legend:ST5|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2020/07/08	2020/08/14	rogid:JA/YbWOU0ieAQ90kq+sS7Ul6iVI10090	rogid:jYoNmHY+G6+S39CX1qRFCxjy0xw83332	rigid:9p83gTI7QQ7MucuYnYJaJ4vUYOg	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P9WIT1	uniprotkb:Q9Z2B5	intact:EBI-25767539|uniprotkb:L0TBU2|uniprotkb:Q50685|uniprotkb:Q7D7C5	intact:EBI-1226344|uniprotkb:Q9CTK8|uniprotkb:Q9CWT5	psi-mi:y2280_myctu(display_long)|uniprotkb:Rv2280(locus name)	psi-mi:e2ak3_mouse(display_long)|uniprotkb:Eif2ak3(gene name)|psi-mi:Eif2ak3(display_short)|uniprotkb:Pek(gene name synonym)|uniprotkb:Perk(gene name synonym)|uniprotkb:PRKR-like endoplasmic reticulum kinase(gene name synonym)|uniprotkb:Pancreatic eIF2-alpha kinase(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2018)	doi:10.1093/nar/gkx1173|imex:IM-28235|pubmed:29165646	taxid:83332(myctu)|taxid:83332("Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)")	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0471"(MINT)	intact:EBI-25768118|imex:IM-28235-185	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	go:"GO:0005618"(cell wall)|go:"GO:0005886"(plasma membrane)|go:"GO:0016491"(oxidoreductase activity)|go:"GO:0071949"(FAD binding)|interpro:IPR016169(CO dehydrogenase flavoprotein-like, FAD-binding, subdomain 2)|mint:P9WIT1|refseq:WP_003411690.1|interpro:IPR016166(FAD-binding, type 2)|interpro:IPR036318|interpro:IPR016164(FAD-linked oxidase-like, C-terminal)|interpro:IPR004113(FAD-linked oxidase, C-terminal)|interpro:IPR006094(FAD linked oxidase, N-terminal)|interpro:IPR016171(Vanillyl-alcohol oxidase, C-terminal subdomain 2)	refseq:NP_001300847.1|mint:Q9Z2B5|dip:DIP-39494N|go:"GO:1902235"(regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway)|go:"GO:1902237"(positive regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway)|go:"GO:1903788"(positive regulation of glutathione biosynthetic process)|go:"GO:1990440"(positive regulation of transcription from RNA polymerase II promoter in response to endoplasmic reticulum stress)|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR011047(Quinonprotein alcohol dehydrogenase-like)|interpro:IPR015943(WD40/YVTN repeat-like)|rcsb pdb:3QD2|rcsb pdb:4YZY|reactome:R-MMU-381042|go:"GO:0001503"(ossification)|go:"GO:0001525"(angiogenesis)|go:"GO:0002063"(chondrocyte development)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0004694"(eukaryotic translation initiation factor 2alpha kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005829"(cytosol)|go:"GO:0006412"(translation)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0006919"(activation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0006983"(ER overload response)|go:"GO:0007029"(endoplasmic reticulum organization)|go:"GO:0007595"(lactation)|go:"GO:0009967"(positive regulation of signal transduction)|go:"GO:0010575"(positive regulation of vascular endothelial growth factor production)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0001501"(skeletal system development)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0010998"(regulation of translational initiation by eIF2 alpha phosphorylation)|go:"GO:0016021"(integral component of membrane)|go:"GO:0017148"(negative regulation of translation)|go:"GO:0018105"(peptidyl-serine phosphorylation)|go:"GO:0019217"(regulation of fatty acid metabolic process)|go:"GO:0019722"(calcium-mediated signaling)|go:"GO:0019899"(enzyme binding)|go:"GO:0019903"(protein phosphatase binding)|go:"GO:0030282"(bone mineralization)|go:"GO:0030433"(ubiquitin-dependent ERAD pathway)|go:"GO:0030968"(endoplasmic reticulum unfolded protein response)|go:"GO:0031016"(pancreas development)|go:"GO:0031018"(endocrine pancreas development)|go:"GO:0031642"(negative regulation of myelination)|go:"GO:0032055"(negative regulation of translation in response to stress)|go:"GO:0032092"(positive regulation of protein binding)|go:"GO:0032933"(SREBP signaling pathway)|go:"GO:0034198"(cellular response to amino acid starvation)|go:"GO:0034976"(response to endoplasmic reticulum stress)|go:"GO:0036492"(eiF2alpha phosphorylation in response to endoplasmic reticulum stress)|go:"GO:0036499"(PERK-mediated unfolded protein response)|go:"GO:0042149"(cellular response to glucose starvation)|go:"GO:0042802"(identical protein binding)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0044322"(endoplasmic reticulum quality control compartment)|go:"GO:0045444"(fat cell differentiation)|go:"GO:0045943"(positive regulation of transcription by RNA polymerase I)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0048009"(insulin-like growth factor receptor signaling pathway)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051879"(Hsp90 protein binding)|go:"GO:0060734"(regulation of endoplasmic reticulum stress-induced eIF2 alpha phosphorylation)|go:"GO:0070059"(intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress)|go:"GO:0070417"(cellular response to cold)|go:"GO:0071074"(eukaryotic initiation factor eIF2 binding)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:1900182"(positive regulation of protein localization to nucleus)|go:"GO:1902010"(negative regulation of translation in response to endoplasmic reticulum stress)	-	-	-	figure legend:ST5|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2020/07/08	2020/08/14	rogid:TvFI3uuw9zREl1q0DeWIsHmCSEk83332	rogid:JA/YbWOU0ieAQ90kq+sS7Ul6iVI10090	rigid:jrHYJVt9LFDowNOGlH4j7RzwKxQ	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:O07177	uniprotkb:Q9Z2B5	intact:EBI-25767633|uniprotkb:L0T5L4	intact:EBI-1226344|uniprotkb:Q9CTK8|uniprotkb:Q9CWT5	psi-mi:mak1_myctu(display_long)|uniprotkb:mak(gene name)|psi-mi:mak(display_short)|uniprotkb:Maltose-1-phosphate synthase(gene name synonym)|uniprotkb:Rv0127(locus name)	psi-mi:e2ak3_mouse(display_long)|uniprotkb:Eif2ak3(gene name)|psi-mi:Eif2ak3(display_short)|uniprotkb:Pek(gene name synonym)|uniprotkb:Perk(gene name synonym)|uniprotkb:PRKR-like endoplasmic reticulum kinase(gene name synonym)|uniprotkb:Pancreatic eIF2-alpha kinase(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2018)	doi:10.1093/nar/gkx1173|imex:IM-28235|pubmed:29165646	taxid:83332(myctu)|taxid:83332("Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)")	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0471"(MINT)	intact:EBI-25768112|imex:IM-28235-87	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	go:"GO:0005978"(glycogen biosynthetic process)|go:"GO:0005992"(trehalose biosynthetic process)|go:"GO:0016301"(kinase activity)|go:"GO:0046835"(carbohydrate phosphorylation)|rcsb pdb:4O7O|rcsb pdb:4O7P|go:"GO:0005524"(ATP binding)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|mint:O07177|refseq:NP_214641.1|refseq:WP_003916610.1|interpro:IPR011009(Protein kinase-like)|interpro:IPR040999	refseq:NP_001300847.1|mint:Q9Z2B5|dip:DIP-39494N|go:"GO:1902235"(regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway)|go:"GO:1902237"(positive regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway)|go:"GO:1903788"(positive regulation of glutathione biosynthetic process)|go:"GO:1990440"(positive regulation of transcription from RNA polymerase II promoter in response to endoplasmic reticulum stress)|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR011047(Quinonprotein alcohol dehydrogenase-like)|interpro:IPR015943(WD40/YVTN repeat-like)|rcsb pdb:3QD2|rcsb pdb:4YZY|reactome:R-MMU-381042|go:"GO:0001503"(ossification)|go:"GO:0001525"(angiogenesis)|go:"GO:0002063"(chondrocyte development)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0004694"(eukaryotic translation initiation factor 2alpha kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005829"(cytosol)|go:"GO:0006412"(translation)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0006919"(activation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0006983"(ER overload response)|go:"GO:0007029"(endoplasmic reticulum organization)|go:"GO:0007595"(lactation)|go:"GO:0009967"(positive regulation of signal transduction)|go:"GO:0010575"(positive regulation of vascular endothelial growth factor production)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0001501"(skeletal system development)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0010998"(regulation of translational initiation by eIF2 alpha phosphorylation)|go:"GO:0016021"(integral component of membrane)|go:"GO:0017148"(negative regulation of translation)|go:"GO:0018105"(peptidyl-serine phosphorylation)|go:"GO:0019217"(regulation of fatty acid metabolic process)|go:"GO:0019722"(calcium-mediated signaling)|go:"GO:0019899"(enzyme binding)|go:"GO:0019903"(protein phosphatase binding)|go:"GO:0030282"(bone mineralization)|go:"GO:0030433"(ubiquitin-dependent ERAD pathway)|go:"GO:0030968"(endoplasmic reticulum unfolded protein response)|go:"GO:0031016"(pancreas development)|go:"GO:0031018"(endocrine pancreas development)|go:"GO:0031642"(negative regulation of myelination)|go:"GO:0032055"(negative regulation of translation in response to stress)|go:"GO:0032092"(positive regulation of protein binding)|go:"GO:0032933"(SREBP signaling pathway)|go:"GO:0034198"(cellular response to amino acid starvation)|go:"GO:0034976"(response to endoplasmic reticulum stress)|go:"GO:0036492"(eiF2alpha phosphorylation in response to endoplasmic reticulum stress)|go:"GO:0036499"(PERK-mediated unfolded protein response)|go:"GO:0042149"(cellular response to glucose starvation)|go:"GO:0042802"(identical protein binding)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0044322"(endoplasmic reticulum quality control compartment)|go:"GO:0045444"(fat cell differentiation)|go:"GO:0045943"(positive regulation of transcription by RNA polymerase I)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0048009"(insulin-like growth factor receptor signaling pathway)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051879"(Hsp90 protein binding)|go:"GO:0060734"(regulation of endoplasmic reticulum stress-induced eIF2 alpha phosphorylation)|go:"GO:0070059"(intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress)|go:"GO:0070417"(cellular response to cold)|go:"GO:0071074"(eukaryotic initiation factor eIF2 binding)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:1900182"(positive regulation of protein localization to nucleus)|go:"GO:1902010"(negative regulation of translation in response to endoplasmic reticulum stress)	-	-	-	figure legend:ST5|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2020/07/08	2020/08/14	rogid:kpl6jZ4UbJUq/kfAlHBYpJAJV4E83332	rogid:JA/YbWOU0ieAQ90kq+sS7Ul6iVI10090	rigid:q6h9zlwEHtYubjqRK2AeAQSaOuk	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:L7N684	uniprotkb:Q9Z2B5	intact:EBI-25768007|uniprotkb:I6XZY1	intact:EBI-1226344|uniprotkb:Q9CTK8|uniprotkb:Q9CWT5	psi-mi:l7n684_myctu(display_long)|uniprotkb:Rv2141c(locus name)	psi-mi:e2ak3_mouse(display_long)|uniprotkb:Eif2ak3(gene name)|psi-mi:Eif2ak3(display_short)|uniprotkb:Pek(gene name synonym)|uniprotkb:Perk(gene name synonym)|uniprotkb:PRKR-like endoplasmic reticulum kinase(gene name synonym)|uniprotkb:Pancreatic eIF2-alpha kinase(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2018)	doi:10.1093/nar/gkx1173|imex:IM-28235|pubmed:29165646	taxid:83332(myctu)|taxid:83332("Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)")	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0471"(MINT)	intact:EBI-25768106|imex:IM-28235-57	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	go:"GO:0006526"(arginine biosynthetic process)|go:"GO:0008777"(acetylornithine deacetylase activity)|mint:L7N684|refseq:WP_003411121.1|refseq:YP_177864.1|interpro:IPR001261(ArgE/DapE/ACY1/CPG2/YscS, conserved site)|interpro:IPR036264|interpro:IPR002933(Peptidase M20)|interpro:IPR011650(Peptidase M20, dimerisation)	refseq:NP_001300847.1|mint:Q9Z2B5|dip:DIP-39494N|go:"GO:1902235"(regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway)|go:"GO:1902237"(positive regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway)|go:"GO:1903788"(positive regulation of glutathione biosynthetic process)|go:"GO:1990440"(positive regulation of transcription from RNA polymerase II promoter in response to endoplasmic reticulum stress)|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR011047(Quinonprotein alcohol dehydrogenase-like)|interpro:IPR015943(WD40/YVTN repeat-like)|rcsb pdb:3QD2|rcsb pdb:4YZY|reactome:R-MMU-381042|go:"GO:0001503"(ossification)|go:"GO:0001525"(angiogenesis)|go:"GO:0002063"(chondrocyte development)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0004694"(eukaryotic translation initiation factor 2alpha kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005829"(cytosol)|go:"GO:0006412"(translation)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0006919"(activation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0006983"(ER overload response)|go:"GO:0007029"(endoplasmic reticulum organization)|go:"GO:0007595"(lactation)|go:"GO:0009967"(positive regulation of signal transduction)|go:"GO:0010575"(positive regulation of vascular endothelial growth factor production)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0001501"(skeletal system development)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0010998"(regulation of translational initiation by eIF2 alpha phosphorylation)|go:"GO:0016021"(integral component of membrane)|go:"GO:0017148"(negative regulation of translation)|go:"GO:0018105"(peptidyl-serine phosphorylation)|go:"GO:0019217"(regulation of fatty acid metabolic process)|go:"GO:0019722"(calcium-mediated signaling)|go:"GO:0019899"(enzyme binding)|go:"GO:0019903"(protein phosphatase binding)|go:"GO:0030282"(bone mineralization)|go:"GO:0030433"(ubiquitin-dependent ERAD pathway)|go:"GO:0030968"(endoplasmic reticulum unfolded protein response)|go:"GO:0031016"(pancreas development)|go:"GO:0031018"(endocrine pancreas development)|go:"GO:0031642"(negative regulation of myelination)|go:"GO:0032055"(negative regulation of translation in response to stress)|go:"GO:0032092"(positive regulation of protein binding)|go:"GO:0032933"(SREBP signaling pathway)|go:"GO:0034198"(cellular response to amino acid starvation)|go:"GO:0034976"(response to endoplasmic reticulum stress)|go:"GO:0036492"(eiF2alpha phosphorylation in response to endoplasmic reticulum stress)|go:"GO:0036499"(PERK-mediated unfolded protein response)|go:"GO:0042149"(cellular response to glucose starvation)|go:"GO:0042802"(identical protein binding)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0044322"(endoplasmic reticulum quality control compartment)|go:"GO:0045444"(fat cell differentiation)|go:"GO:0045943"(positive regulation of transcription by RNA polymerase I)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0048009"(insulin-like growth factor receptor signaling pathway)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051879"(Hsp90 protein binding)|go:"GO:0060734"(regulation of endoplasmic reticulum stress-induced eIF2 alpha phosphorylation)|go:"GO:0070059"(intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress)|go:"GO:0070417"(cellular response to cold)|go:"GO:0071074"(eukaryotic initiation factor eIF2 binding)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:1900182"(positive regulation of protein localization to nucleus)|go:"GO:1902010"(negative regulation of translation in response to endoplasmic reticulum stress)	-	-	-	figure legend:ST5|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2020/07/08	2020/08/14	rogid:c/gr5TMeB+nx0CZHLBZI7YeVioo83332	rogid:JA/YbWOU0ieAQ90kq+sS7Ul6iVI10090	rigid:AyqcdngHiddwZC6pctbYz+NacgQ	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P9WN37	uniprotkb:Q9Z2B5	intact:EBI-25767601|uniprotkb:L0T968|uniprotkb:P64245|uniprotkb:Q10378	intact:EBI-1226344|uniprotkb:Q9CTK8|uniprotkb:Q9CWT5	psi-mi:gln1a_myctu(display_long)|uniprotkb:glnA2(gene name)|psi-mi:glnA2(display_short)|uniprotkb:Glutamate--ammonia ligase(gene name synonym)|uniprotkb:Glutamine synthetase I alpha(gene name synonym)|uniprotkb:MTCY190.33c(orf name)|uniprotkb:MTCY427.03c(orf name)|uniprotkb:Rv2222c(locus name)	psi-mi:e2ak3_mouse(display_long)|uniprotkb:Eif2ak3(gene name)|psi-mi:Eif2ak3(display_short)|uniprotkb:Pek(gene name synonym)|uniprotkb:Perk(gene name synonym)|uniprotkb:PRKR-like endoplasmic reticulum kinase(gene name synonym)|uniprotkb:Pancreatic eIF2-alpha kinase(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2018)	doi:10.1093/nar/gkx1173|imex:IM-28235|pubmed:29165646	taxid:83332(myctu)|taxid:83332("Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)")	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0471"(MINT)	intact:EBI-25768100|imex:IM-28235-317	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	go:"GO:0004356"(glutamate-ammonia ligase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0006542"(glutamine biosynthetic process)|go:"GO:0046872"(metal ion binding)|go:"GO:0050001"(D-glutaminase activity)|mint:P9WN37|refseq:NP_216738.1|refseq:WP_003411482.1|interpro:IPR008147(Glutamine synthetase, beta-Grasp)|interpro:IPR036651|interpro:IPR014746(Glutamine synthetase/guanido kinase, catalytic region)|interpro:IPR008146(Glutamine synthetase, catalytic region)|interpro:IPR027303	refseq:NP_001300847.1|mint:Q9Z2B5|dip:DIP-39494N|go:"GO:1902235"(regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway)|go:"GO:1902237"(positive regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway)|go:"GO:1903788"(positive regulation of glutathione biosynthetic process)|go:"GO:1990440"(positive regulation of transcription from RNA polymerase II promoter in response to endoplasmic reticulum stress)|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR011047(Quinonprotein alcohol dehydrogenase-like)|interpro:IPR015943(WD40/YVTN repeat-like)|rcsb pdb:3QD2|rcsb pdb:4YZY|reactome:R-MMU-381042|go:"GO:0001503"(ossification)|go:"GO:0001525"(angiogenesis)|go:"GO:0002063"(chondrocyte development)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0004694"(eukaryotic translation initiation factor 2alpha kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005829"(cytosol)|go:"GO:0006412"(translation)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0006919"(activation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0006983"(ER overload response)|go:"GO:0007029"(endoplasmic reticulum organization)|go:"GO:0007595"(lactation)|go:"GO:0009967"(positive regulation of signal transduction)|go:"GO:0010575"(positive regulation of vascular endothelial growth factor production)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0001501"(skeletal system development)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0010998"(regulation of translational initiation by eIF2 alpha phosphorylation)|go:"GO:0016021"(integral component of membrane)|go:"GO:0017148"(negative regulation of translation)|go:"GO:0018105"(peptidyl-serine phosphorylation)|go:"GO:0019217"(regulation of fatty acid metabolic process)|go:"GO:0019722"(calcium-mediated signaling)|go:"GO:0019899"(enzyme binding)|go:"GO:0019903"(protein phosphatase binding)|go:"GO:0030282"(bone mineralization)|go:"GO:0030433"(ubiquitin-dependent ERAD pathway)|go:"GO:0030968"(endoplasmic reticulum unfolded protein response)|go:"GO:0031016"(pancreas development)|go:"GO:0031018"(endocrine pancreas development)|go:"GO:0031642"(negative regulation of myelination)|go:"GO:0032055"(negative regulation of translation in response to stress)|go:"GO:0032092"(positive regulation of protein binding)|go:"GO:0032933"(SREBP signaling pathway)|go:"GO:0034198"(cellular response to amino acid starvation)|go:"GO:0034976"(response to endoplasmic reticulum stress)|go:"GO:0036492"(eiF2alpha phosphorylation in response to endoplasmic reticulum stress)|go:"GO:0036499"(PERK-mediated unfolded protein response)|go:"GO:0042149"(cellular response to glucose starvation)|go:"GO:0042802"(identical protein binding)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0044322"(endoplasmic reticulum quality control compartment)|go:"GO:0045444"(fat cell differentiation)|go:"GO:0045943"(positive regulation of transcription by RNA polymerase I)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0048009"(insulin-like growth factor receptor signaling pathway)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051879"(Hsp90 protein binding)|go:"GO:0060734"(regulation of endoplasmic reticulum stress-induced eIF2 alpha phosphorylation)|go:"GO:0070059"(intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress)|go:"GO:0070417"(cellular response to cold)|go:"GO:0071074"(eukaryotic initiation factor eIF2 binding)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:1900182"(positive regulation of protein localization to nucleus)|go:"GO:1902010"(negative regulation of translation in response to endoplasmic reticulum stress)	-	-	-	figure legend:ST5|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2020/07/08	2020/08/14	rogid:LDIpolmw5yhv2iG5+8HKbWlwT8883332	rogid:JA/YbWOU0ieAQ90kq+sS7Ul6iVI10090	rigid:3G22Qxkf3HO07+OVvuLgsKlhnPE	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:O50440	uniprotkb:Q8K4B2	intact:EBI-25767742|uniprotkb:I6XXB2|uniprotkb:L0T7J5	intact:EBI-646179|uniprotkb:Q8C7U8|uniprotkb:Q8CE40|uniprotkb:Q8K1S8|ensembl:ENSMUSP00000020448	psi-mi:chp2_myctu(display_long)|uniprotkb:chp2(gene name)|psi-mi:chp2(display_short)|uniprotkb:LH57_06500(orf name)|uniprotkb:P425_01234(orf name)|uniprotkb:Rv1184c(locus name)|uniprotkb:RVBD_1184c(locus name)	psi-mi:irak3_mouse(display_long)|uniprotkb:IL-1 receptor-associated kinase M(gene name synonym)|uniprotkb:Irak3(gene name)|psi-mi:Irak3(display_short)|uniprotkb:Inactive IL-1 receptor-associated kinase 3(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2018)	doi:10.1093/nar/gkx1173|imex:IM-28235|pubmed:29165646	taxid:83332(myctu)|taxid:83332("Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)")	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0471"(MINT)	intact:EBI-25768094|imex:IM-28235-137	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	go:"GO:0005886"(plasma membrane)|go:"GO:0006629"(lipid metabolic process)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016746"(acyltransferase activity)|go:"GO:0005618"(cell wall)|mint:O50440|refseq:NP_215700.1|refseq:WP_003406195.1|interpro:IPR013228(PE-PPE, C-terminal)	refseq:NP_082955.2|go:"GO:0001960"(negative regulation of cytokine-mediated signaling pathway)|go:"GO:0002755"(MyD88-dependent toll-like receptor signaling pathway)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0009615"(response to virus)|go:"GO:0010933"(positive regulation of macrophage tolerance induction)|go:"GO:0010936"(negative regulation of macrophage cytokine production)|go:"GO:0019221"(cytokine-mediated signaling pathway)|go:"GO:0019901"(protein kinase binding)|go:"GO:0032088"(negative regulation of NF-kappaB transcription factor activity)|go:"GO:0032494"(response to peptidoglycan)|go:"GO:0032496"(response to lipopolysaccharide)|go:"GO:0032695"(negative regulation of interleukin-12 production)|go:"GO:0032715"(negative regulation of interleukin-6 production)|go:"GO:0032720"(negative regulation of tumor necrosis factor production)|go:"GO:0034122"(negative regulation of toll-like receptor signaling pathway)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0042177"(negative regulation of protein catabolic process)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043242"(negative regulation of protein-containing complex disassembly)|go:"GO:0043244"(regulation of protein-containing complex disassembly)|go:"GO:0043330"(response to exogenous dsRNA)|go:"GO:0043407"(negative regulation of MAP kinase activity)|go:"GO:0045824"(negative regulation of innate immune response)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|go:"GO:0070498"(interleukin-1-mediated signaling pathway)|go:"GO:0070555"(response to interleukin-1)|interpro:IPR000488(Death)|interpro:IPR000719(Protein kinase, core)|interpro:IPR011009(Protein kinase-like)|interpro:IPR011029(DEATH-like)|interpro:IPR033610|interpro:IPR042698|interpro:IPR042747|mint:Q8K4B2|reactome:R-MMU-9020702|ensembl:ENSMUSG00000020227(gene)|ensembl:ENSMUST00000020448(transcript)|go:"GO:0000287"(magnesium ion binding)|go:"GO:0001819"(positive regulation of cytokine production)	-	-	-	figure legend:ST5|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2020/07/08	2020/08/14	rogid:IXzYfb7UxFgqBXPZ6NZHLy3hdTc83332	rogid:oIjgqYFjr3oyFSGixSb2jrq03Cc10090	rigid:u05eTT3DYaE48KAO8I4lrvvMQxc	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:I6YC03	uniprotkb:Q8K4B2	intact:EBI-25768074	intact:EBI-646179|uniprotkb:Q8C7U8|uniprotkb:Q8CE40|uniprotkb:Q8K1S8|ensembl:ENSMUSP00000020448	psi-mi:ephb_myctu(display_long)|uniprotkb:ephB(gene name)|psi-mi:ephB(display_short)|uniprotkb:Epoxide hydrolase EphB(gene name synonym)|uniprotkb:LH57_10545(orf name)|uniprotkb:Rv1938(locus name)	psi-mi:irak3_mouse(display_long)|uniprotkb:IL-1 receptor-associated kinase M(gene name synonym)|uniprotkb:Irak3(gene name)|psi-mi:Irak3(display_short)|uniprotkb:Inactive IL-1 receptor-associated kinase 3(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2018)	doi:10.1093/nar/gkx1173|imex:IM-28235|pubmed:29165646	taxid:83332(myctu)|taxid:83332("Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)")	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0471"(MINT)	intact:EBI-25768088|imex:IM-28235-135	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	go:"GO:0009636"(response to toxic substance)|go:"GO:0016787"(hydrolase activity)|go:"GO:0018742"(epoxide hydrolase B activity)|go:"GO:0042803"(protein homodimerization activity)|mint:I6YC03|refseq:NP_216454.1|refseq:WP_003899091.1|interpro:IPR029058|interpro:IPR000073(Alpha/beta hydrolase fold-1)|interpro:IPR000639(Epoxide hydrolase-like)	refseq:NP_082955.2|go:"GO:0001960"(negative regulation of cytokine-mediated signaling pathway)|go:"GO:0002755"(MyD88-dependent toll-like receptor signaling pathway)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0009615"(response to virus)|go:"GO:0010933"(positive regulation of macrophage tolerance induction)|go:"GO:0010936"(negative regulation of macrophage cytokine production)|go:"GO:0019221"(cytokine-mediated signaling pathway)|go:"GO:0019901"(protein kinase binding)|go:"GO:0032088"(negative regulation of NF-kappaB transcription factor activity)|go:"GO:0032494"(response to peptidoglycan)|go:"GO:0032496"(response to lipopolysaccharide)|go:"GO:0032695"(negative regulation of interleukin-12 production)|go:"GO:0032715"(negative regulation of interleukin-6 production)|go:"GO:0032720"(negative regulation of tumor necrosis factor production)|go:"GO:0034122"(negative regulation of toll-like receptor signaling pathway)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0042177"(negative regulation of protein catabolic process)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043242"(negative regulation of protein-containing complex disassembly)|go:"GO:0043244"(regulation of protein-containing complex disassembly)|go:"GO:0043330"(response to exogenous dsRNA)|go:"GO:0043407"(negative regulation of MAP kinase activity)|go:"GO:0045824"(negative regulation of innate immune response)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|go:"GO:0070498"(interleukin-1-mediated signaling pathway)|go:"GO:0070555"(response to interleukin-1)|interpro:IPR000488(Death)|interpro:IPR000719(Protein kinase, core)|interpro:IPR011009(Protein kinase-like)|interpro:IPR011029(DEATH-like)|interpro:IPR033610|interpro:IPR042698|interpro:IPR042747|mint:Q8K4B2|reactome:R-MMU-9020702|ensembl:ENSMUSG00000020227(gene)|ensembl:ENSMUST00000020448(transcript)|go:"GO:0000287"(magnesium ion binding)|go:"GO:0001819"(positive regulation of cytokine production)	-	-	-	figure legend:ST5|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2020/07/08	2020/08/14	rogid:sRxqN+k+jfx7zSE+ctNP+i+id0I83332	rogid:oIjgqYFjr3oyFSGixSb2jrq03Cc10090	rigid:Be0oZ7T4PfTDndPJIActdxhwG+g	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P9WHT9	uniprotkb:Q8K4B2	intact:EBI-7947958|uniprotkb:O33245|intact:MINT-7985947|uniprotkb:Q7D7I2|uniprotkb:L0T8V8	intact:EBI-646179|uniprotkb:Q8C7U8|uniprotkb:Q8CE40|uniprotkb:Q8K1S8|ensembl:ENSMUSP00000020448	psi-mi:psb_myctu(display_long)|uniprotkb:Proteasome core protein PrcB(gene name synonym)|uniprotkb:Rv2110c(locus name)|uniprotkb:prcB(gene name)|psi-mi:prcB(display_short)|uniprotkb:20S proteasome beta subunit(gene name synonym)	psi-mi:irak3_mouse(display_long)|uniprotkb:IL-1 receptor-associated kinase M(gene name synonym)|uniprotkb:Irak3(gene name)|psi-mi:Irak3(display_short)|uniprotkb:Inactive IL-1 receptor-associated kinase 3(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2018)	doi:10.1093/nar/gkx1173|imex:IM-28235|pubmed:29165646	taxid:83332(myctu)|taxid:83332("Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)")	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0471"(MINT)	intact:EBI-25768068|imex:IM-28235-55	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	interpro:IPR029055|refseq:WP_003411023.1|interpro:IPR001353(20S proteasome, A and B subunits)|refseq:NP_216626.1|interpro:IPR023333|interpro:IPR022483|mint:P9WHT9|go:"GO:0004298"(threonine-type endopeptidase activity)|go:"GO:0005576"(extracellular region)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0010498"(proteasomal protein catabolic process)|go:"GO:0019773"(proteasome core complex, alpha-subunit complex)|go:"GO:0019774"(proteasome core complex, beta-subunit complex)|go:"GO:0019941"(modification-dependent protein catabolic process)|go:"GO:0030682"(mitigation of host defenses by symbiont)|go:"GO:0035375"(zymogen binding)|go:"GO:0051603"(proteolysis involved in cellular protein catabolic process)|rcsb pdb:2FHG|rcsb pdb:2FHH|rcsb pdb:2JAY|rcsb pdb:3H6F|rcsb pdb:3H6I|rcsb pdb:3HF9|rcsb pdb:3HFA|rcsb pdb:3KRD|rcsb pdb:3MFE|rcsb pdb:3MI0|rcsb pdb:3MKA|rcsb pdb:5LZP|rcsb pdb:5THO|rcsb pdb:5TRG|rcsb pdb:5TRR|rcsb pdb:5TRS|rcsb pdb:5TRY|rcsb pdb:5TS0|rcsb pdb:6BGL|rcsb pdb:6BGO|rcsb pdb:6OCW|rcsb pdb:6OCZ|rcsb pdb:6ODE	refseq:NP_082955.2|go:"GO:0001960"(negative regulation of cytokine-mediated signaling pathway)|go:"GO:0002755"(MyD88-dependent toll-like receptor signaling pathway)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0009615"(response to virus)|go:"GO:0010933"(positive regulation of macrophage tolerance induction)|go:"GO:0010936"(negative regulation of macrophage cytokine production)|go:"GO:0019221"(cytokine-mediated signaling pathway)|go:"GO:0019901"(protein kinase binding)|go:"GO:0032088"(negative regulation of NF-kappaB transcription factor activity)|go:"GO:0032494"(response to peptidoglycan)|go:"GO:0032496"(response to lipopolysaccharide)|go:"GO:0032695"(negative regulation of interleukin-12 production)|go:"GO:0032715"(negative regulation of interleukin-6 production)|go:"GO:0032720"(negative regulation of tumor necrosis factor production)|go:"GO:0034122"(negative regulation of toll-like receptor signaling pathway)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0042177"(negative regulation of protein catabolic process)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043242"(negative regulation of protein-containing complex disassembly)|go:"GO:0043244"(regulation of protein-containing complex disassembly)|go:"GO:0043330"(response to exogenous dsRNA)|go:"GO:0043407"(negative regulation of MAP kinase activity)|go:"GO:0045824"(negative regulation of innate immune response)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|go:"GO:0070498"(interleukin-1-mediated signaling pathway)|go:"GO:0070555"(response to interleukin-1)|interpro:IPR000488(Death)|interpro:IPR000719(Protein kinase, core)|interpro:IPR011009(Protein kinase-like)|interpro:IPR011029(DEATH-like)|interpro:IPR033610|interpro:IPR042698|interpro:IPR042747|mint:Q8K4B2|reactome:R-MMU-9020702|ensembl:ENSMUSG00000020227(gene)|ensembl:ENSMUST00000020448(transcript)|go:"GO:0000287"(magnesium ion binding)|go:"GO:0001819"(positive regulation of cytokine production)	-	crc64:3FC3FCD81231E129|comment:mint	-	figure legend:ST5|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2020/07/08	2020/08/14	rogid:hQ8Eci/BIL/quaWNhklTdFRPHDI83332	rogid:oIjgqYFjr3oyFSGixSb2jrq03Cc10090	rigid:JML3Y1ZHdw0d4Xl4Fa8leX1GtJo	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:I6Y946	uniprotkb:Q8K4B2	intact:EBI-25767727	intact:EBI-646179|uniprotkb:Q8C7U8|uniprotkb:Q8CE40|uniprotkb:Q8K1S8|ensembl:ENSMUSP00000020448	psi-mi:i6y946_myctu(display_long)|uniprotkb:Rv0925c(locus name)	psi-mi:irak3_mouse(display_long)|uniprotkb:IL-1 receptor-associated kinase M(gene name synonym)|uniprotkb:Irak3(gene name)|psi-mi:Irak3(display_short)|uniprotkb:Inactive IL-1 receptor-associated kinase 3(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2018)	doi:10.1093/nar/gkx1173|imex:IM-28235|pubmed:29165646	taxid:83332(myctu)|taxid:83332("Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)")	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0471"(MINT)	intact:EBI-25768062|imex:IM-28235-315	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	go:"GO:0016491"(oxidoreductase activity)|mint:I6Y946|refseq:NP_215440.1|refseq:WP_003404764.1|interpro:IPR029039|interpro:IPR005025(NADPH-dependent FMN reductase)	refseq:NP_082955.2|go:"GO:0001960"(negative regulation of cytokine-mediated signaling pathway)|go:"GO:0002755"(MyD88-dependent toll-like receptor signaling pathway)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0009615"(response to virus)|go:"GO:0010933"(positive regulation of macrophage tolerance induction)|go:"GO:0010936"(negative regulation of macrophage cytokine production)|go:"GO:0019221"(cytokine-mediated signaling pathway)|go:"GO:0019901"(protein kinase binding)|go:"GO:0032088"(negative regulation of NF-kappaB transcription factor activity)|go:"GO:0032494"(response to peptidoglycan)|go:"GO:0032496"(response to lipopolysaccharide)|go:"GO:0032695"(negative regulation of interleukin-12 production)|go:"GO:0032715"(negative regulation of interleukin-6 production)|go:"GO:0032720"(negative regulation of tumor necrosis factor production)|go:"GO:0034122"(negative regulation of toll-like receptor signaling pathway)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0042177"(negative regulation of protein catabolic process)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043242"(negative regulation of protein-containing complex disassembly)|go:"GO:0043244"(regulation of protein-containing complex disassembly)|go:"GO:0043330"(response to exogenous dsRNA)|go:"GO:0043407"(negative regulation of MAP kinase activity)|go:"GO:0045824"(negative regulation of innate immune response)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|go:"GO:0070498"(interleukin-1-mediated signaling pathway)|go:"GO:0070555"(response to interleukin-1)|interpro:IPR000488(Death)|interpro:IPR000719(Protein kinase, core)|interpro:IPR011009(Protein kinase-like)|interpro:IPR011029(DEATH-like)|interpro:IPR033610|interpro:IPR042698|interpro:IPR042747|mint:Q8K4B2|reactome:R-MMU-9020702|ensembl:ENSMUSG00000020227(gene)|ensembl:ENSMUST00000020448(transcript)|go:"GO:0000287"(magnesium ion binding)|go:"GO:0001819"(positive regulation of cytokine production)	-	-	-	figure legend:ST5|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2020/07/08	2020/08/14	rogid:JOW06LtizimdrjJdMmMnM9ru8n083332	rogid:oIjgqYFjr3oyFSGixSb2jrq03Cc10090	rigid:rt9C/L/cOSlp4MRdZuEU6dk9g6g	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P9WJB9	uniprotkb:Q8K4B2	intact:EBI-25767670|uniprotkb:L0TE21|uniprotkb:O69744|uniprotkb:Q7D4P0	intact:EBI-646179|uniprotkb:Q8C7U8|uniprotkb:Q8CE40|uniprotkb:Q8K1S8|ensembl:ENSMUSP00000020448	psi-mi:espl_myctu(display_long)|uniprotkb:espL(gene name)|psi-mi:espL(display_short)|uniprotkb:Rv3880c(locus name)	psi-mi:irak3_mouse(display_long)|uniprotkb:IL-1 receptor-associated kinase M(gene name synonym)|uniprotkb:Irak3(gene name)|psi-mi:Irak3(display_short)|uniprotkb:Inactive IL-1 receptor-associated kinase 3(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2018)	doi:10.1093/nar/gkx1173|imex:IM-28235|pubmed:29165646	taxid:83332(myctu)|taxid:83332("Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)")	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0471"(MINT)	intact:EBI-25768050|imex:IM-28235-53	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	go:"GO:0003677"(DNA binding)|go:"GO:0005618"(cell wall)|go:"GO:0005886"(plasma membrane)|go:"GO:0052170"(suppression by symbiont of host innate immune response)|mint:P9WJB9|refseq:NP_218397.1|refseq:WP_003399988.1|interpro:IPR036894|interpro:IPR004401(Conserved hypothetical protein CHP00103)	refseq:NP_082955.2|go:"GO:0001960"(negative regulation of cytokine-mediated signaling pathway)|go:"GO:0002755"(MyD88-dependent toll-like receptor signaling pathway)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0009615"(response to virus)|go:"GO:0010933"(positive regulation of macrophage tolerance induction)|go:"GO:0010936"(negative regulation of macrophage cytokine production)|go:"GO:0019221"(cytokine-mediated signaling pathway)|go:"GO:0019901"(protein kinase binding)|go:"GO:0032088"(negative regulation of NF-kappaB transcription factor activity)|go:"GO:0032494"(response to peptidoglycan)|go:"GO:0032496"(response to lipopolysaccharide)|go:"GO:0032695"(negative regulation of interleukin-12 production)|go:"GO:0032715"(negative regulation of interleukin-6 production)|go:"GO:0032720"(negative regulation of tumor necrosis factor production)|go:"GO:0034122"(negative regulation of toll-like receptor signaling pathway)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0042177"(negative regulation of protein catabolic process)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043242"(negative regulation of protein-containing complex disassembly)|go:"GO:0043244"(regulation of protein-containing complex disassembly)|go:"GO:0043330"(response to exogenous dsRNA)|go:"GO:0043407"(negative regulation of MAP kinase activity)|go:"GO:0045824"(negative regulation of innate immune response)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|go:"GO:0070498"(interleukin-1-mediated signaling pathway)|go:"GO:0070555"(response to interleukin-1)|interpro:IPR000488(Death)|interpro:IPR000719(Protein kinase, core)|interpro:IPR011009(Protein kinase-like)|interpro:IPR011029(DEATH-like)|interpro:IPR033610|interpro:IPR042698|interpro:IPR042747|mint:Q8K4B2|reactome:R-MMU-9020702|ensembl:ENSMUSG00000020227(gene)|ensembl:ENSMUST00000020448(transcript)|go:"GO:0000287"(magnesium ion binding)|go:"GO:0001819"(positive regulation of cytokine production)	-	-	-	figure legend:ST5|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2020/07/08	2020/08/14	rogid:BspTx2RZuhJaQ319NBDIyOreqfE83332	rogid:oIjgqYFjr3oyFSGixSb2jrq03Cc10090	rigid:g77jeYw4d6FHLOgu3J2n8RpQAjQ	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q80U62	uniprotkb:P9WNI7	intact:EBI-3506572|uniprotkb:Q3TAX3|uniprotkb:Q3TD96|uniprotkb:Q3TDF7|uniprotkb:Q3TDU2|uniprotkb:Q6NWW8|uniprotkb:Q6P9T7|uniprotkb:Q6PG18|uniprotkb:Q8BMP7|uniprotkb:Q8BY22|ensembl:ENSMUSP00000087114	intact:EBI-9027314|uniprotkb:P95242|uniprotkb:L0T9C9	psi-mi:rubic_mouse(display_long)|uniprotkb:Rubcn(gene name)|psi-mi:Rubcn(display_short)|uniprotkb:Kiaa0226(gene name synonym)	psi-mi:esxo_myctu(display_long)|uniprotkb:esxO(gene name)|psi-mi:esxO(display_short)|uniprotkb:MTCY98.15c(orf name)|uniprotkb:Rv2346c(locus name)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2018)	doi:10.1093/nar/gkx1173|imex:IM-28235|pubmed:29165646	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:83332(myctu)|taxid:83332("Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)")	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0471"(MINT)	intact:EBI-25768376|imex:IM-28235-67	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001186967.1|refseq:NP_766203.1|ensembl:ENSMUSG00000035629(gene)|ensembl:ENSMUST00000089684(transcript)|go:"GO:0002376"(immune system process)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005764"(lysosome)|go:"GO:0005769"(early endosome)|go:"GO:0005770"(late endosome)|go:"GO:0005829"(cytosol)|go:"GO:0006897"(endocytosis)|go:"GO:0006914"(autophagy)|go:"GO:0010507"(negative regulation of autophagy)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0043553"(negative regulation of phosphatidylinositol 3-kinase activity)|go:"GO:0045806"(negative regulation of endocytosis)|go:"GO:1901097"(negative regulation of autophagosome maturation)|go:"GO:1901981"(phosphatidylinositol phosphate binding)|interpro:IPR004012(RUN)|interpro:IPR025258|interpro:IPR037213|mint:Q80U62	mint:P9WNI7|interpro:IPR036689|interpro:IPR009416(Protein of unknown function DUF1066)|interpro:IPR010310(Protein of unknown function DUF909)|refseq:NP_216862.1|refseq:WP_003899283.1|go:"GO:0005576"(extracellular region)|go:"GO:0005618"(cell wall)|go:"GO:0005886"(plasma membrane)|rcsb pdb:3OGI|rcsb pdb:4GZR	-	-	-	figure legend:ST5|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2020/07/08	2020/08/14	rogid:W9a7lLJWOl9czZuUTzBr+Nfyaqw10090	rogid:jYoNmHY+G6+S39CX1qRFCxjy0xw83332	rigid:y0+W9Zwr/CZmg6k8E+uN/PACNpE	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P9WIT1	uniprotkb:O35718	intact:EBI-25767539|uniprotkb:L0TBU2|uniprotkb:Q50685|uniprotkb:Q7D7C5	intact:EBI-2659360|uniprotkb:Q3U7X5|uniprotkb:P97803|ensembl:ENSMUSP00000059129	psi-mi:y2280_myctu(display_long)|uniprotkb:Rv2280(locus name)	psi-mi:socs3_mouse(display_long)|uniprotkb:Cytokine-inducible SH2 protein 3(gene name synonym)|uniprotkb:Protein EF-10(gene name synonym)|uniprotkb:Cis3(gene name synonym)|uniprotkb:Cish3(gene name synonym)|uniprotkb:Socs3(gene name)|psi-mi:Socs3(display_short)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2018)	doi:10.1093/nar/gkx1173|imex:IM-28235|pubmed:29165646	taxid:83332(myctu)|taxid:83332("Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)")	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0471"(MINT)	intact:EBI-25768466|imex:IM-28235-157	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	go:"GO:0005618"(cell wall)|go:"GO:0005886"(plasma membrane)|go:"GO:0016491"(oxidoreductase activity)|go:"GO:0071949"(FAD binding)|interpro:IPR016169(CO dehydrogenase flavoprotein-like, FAD-binding, subdomain 2)|mint:P9WIT1|refseq:WP_003411690.1|interpro:IPR016166(FAD-binding, type 2)|interpro:IPR036318|interpro:IPR016164(FAD-linked oxidase-like, C-terminal)|interpro:IPR004113(FAD-linked oxidase, C-terminal)|interpro:IPR006094(FAD linked oxidase, N-terminal)|interpro:IPR016171(Vanillyl-alcohol oxidase, C-terminal subdomain 2)	refseq:XP_011247009.1|refseq:NP_031733.1|ensembl:ENSMUSG00000053113(gene)|ensembl:ENSMUST00000054002(transcript)|go:"GO:0001784"(phosphotyrosine residue binding)|go:"GO:0001932"(regulation of protein phosphorylation)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005942"(phosphatidylinositol 3-kinase complex)|go:"GO:0007165"(signal transduction)|go:"GO:0007259"(receptor signaling pathway via JAK-STAT)|go:"GO:0009968"(negative regulation of signal transduction)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0040008"(regulation of growth)|go:"GO:0042532"(negative regulation of tyrosine phosphorylation of STAT protein)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0045595"(regulation of cell differentiation)|go:"GO:0045597"(positive regulation of cell differentiation)|go:"GO:0046426"(negative regulation of receptor signaling pathway via JAK-STAT)|go:"GO:0046627"(negative regulation of insulin receptor signaling pathway)|go:"GO:0046854"(phosphatidylinositol phosphate biosynthetic process)|go:"GO:0046935"(1-phosphatidylinositol-3-kinase regulator activity)|go:"GO:0050728"(negative regulation of inflammatory response)|go:"GO:0060670"(branching involved in labyrinthine layer morphogenesis)|go:"GO:0060674"(placenta blood vessel development)|go:"GO:0060707"(trophoblast giant cell differentiation)|go:"GO:0060708"(spongiotrophoblast differentiation)|go:"GO:1990830"(cellular response to leukemia inhibitory factor)|interpro:IPR000980(SH2 motif)|interpro:IPR001496(SOCS protein, C-terminal)|interpro:IPR028414|interpro:IPR035863|interpro:IPR036036|interpro:IPR036860|mint:O35718|rcsb pdb:2BBU|rcsb pdb:2HMH|rcsb pdb:2JZ3|rcsb pdb:4GL9|reactome:R-MMU-1059683|reactome:R-MMU-877300|reactome:R-MMU-877312|reactome:R-MMU-8849474|reactome:R-MMU-8951664|reactome:R-MMU-909733|reactome:R-MMU-9705462|reactome:R-MMU-983168|dip:DIP-29137N	-	-	-	figure legend:ST5|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2020/07/08	2020/08/14	rogid:TvFI3uuw9zREl1q0DeWIsHmCSEk83332	rogid:SFk8FM1xo7SkodsiFXZYzTbLrYg10090	rigid:oLCEil2qV+4xNZPWwRd3mayvO1Q	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:O07177	uniprotkb:O35718	intact:EBI-25767633|uniprotkb:L0T5L4	intact:EBI-2659360|uniprotkb:Q3U7X5|uniprotkb:P97803|ensembl:ENSMUSP00000059129	psi-mi:mak1_myctu(display_long)|uniprotkb:mak(gene name)|psi-mi:mak(display_short)|uniprotkb:Maltose-1-phosphate synthase(gene name synonym)|uniprotkb:Rv0127(locus name)	psi-mi:socs3_mouse(display_long)|uniprotkb:Cytokine-inducible SH2 protein 3(gene name synonym)|uniprotkb:Protein EF-10(gene name synonym)|uniprotkb:Cis3(gene name synonym)|uniprotkb:Cish3(gene name synonym)|uniprotkb:Socs3(gene name)|psi-mi:Socs3(display_short)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2018)	doi:10.1093/nar/gkx1173|imex:IM-28235|pubmed:29165646	taxid:83332(myctu)|taxid:83332("Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)")	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0471"(MINT)	intact:EBI-25768460|imex:IM-28235-75	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	go:"GO:0005978"(glycogen biosynthetic process)|go:"GO:0005992"(trehalose biosynthetic process)|go:"GO:0016301"(kinase activity)|go:"GO:0046835"(carbohydrate phosphorylation)|rcsb pdb:4O7O|rcsb pdb:4O7P|go:"GO:0005524"(ATP binding)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|mint:O07177|refseq:NP_214641.1|refseq:WP_003916610.1|interpro:IPR011009(Protein kinase-like)|interpro:IPR040999	refseq:XP_011247009.1|refseq:NP_031733.1|ensembl:ENSMUSG00000053113(gene)|ensembl:ENSMUST00000054002(transcript)|go:"GO:0001784"(phosphotyrosine residue binding)|go:"GO:0001932"(regulation of protein phosphorylation)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005942"(phosphatidylinositol 3-kinase complex)|go:"GO:0007165"(signal transduction)|go:"GO:0007259"(receptor signaling pathway via JAK-STAT)|go:"GO:0009968"(negative regulation of signal transduction)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0040008"(regulation of growth)|go:"GO:0042532"(negative regulation of tyrosine phosphorylation of STAT protein)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0045595"(regulation of cell differentiation)|go:"GO:0045597"(positive regulation of cell differentiation)|go:"GO:0046426"(negative regulation of receptor signaling pathway via JAK-STAT)|go:"GO:0046627"(negative regulation of insulin receptor signaling pathway)|go:"GO:0046854"(phosphatidylinositol phosphate biosynthetic process)|go:"GO:0046935"(1-phosphatidylinositol-3-kinase regulator activity)|go:"GO:0050728"(negative regulation of inflammatory response)|go:"GO:0060670"(branching involved in labyrinthine layer morphogenesis)|go:"GO:0060674"(placenta blood vessel development)|go:"GO:0060707"(trophoblast giant cell differentiation)|go:"GO:0060708"(spongiotrophoblast differentiation)|go:"GO:1990830"(cellular response to leukemia inhibitory factor)|interpro:IPR000980(SH2 motif)|interpro:IPR001496(SOCS protein, C-terminal)|interpro:IPR028414|interpro:IPR035863|interpro:IPR036036|interpro:IPR036860|mint:O35718|rcsb pdb:2BBU|rcsb pdb:2HMH|rcsb pdb:2JZ3|rcsb pdb:4GL9|reactome:R-MMU-1059683|reactome:R-MMU-877300|reactome:R-MMU-877312|reactome:R-MMU-8849474|reactome:R-MMU-8951664|reactome:R-MMU-909733|reactome:R-MMU-9705462|reactome:R-MMU-983168|dip:DIP-29137N	-	-	-	figure legend:ST5|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2020/07/08	2020/08/14	rogid:kpl6jZ4UbJUq/kfAlHBYpJAJV4E83332	rogid:SFk8FM1xo7SkodsiFXZYzTbLrYg10090	rigid:4a5BNJaIGQUrhyOKHScXwyogm/8	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P9WN37	uniprotkb:O35718	intact:EBI-25767601|uniprotkb:L0T968|uniprotkb:P64245|uniprotkb:Q10378	intact:EBI-2659360|uniprotkb:Q3U7X5|uniprotkb:P97803|ensembl:ENSMUSP00000059129	psi-mi:gln1a_myctu(display_long)|uniprotkb:glnA2(gene name)|psi-mi:glnA2(display_short)|uniprotkb:Glutamate--ammonia ligase(gene name synonym)|uniprotkb:Glutamine synthetase I alpha(gene name synonym)|uniprotkb:MTCY190.33c(orf name)|uniprotkb:MTCY427.03c(orf name)|uniprotkb:Rv2222c(locus name)	psi-mi:socs3_mouse(display_long)|uniprotkb:Cytokine-inducible SH2 protein 3(gene name synonym)|uniprotkb:Protein EF-10(gene name synonym)|uniprotkb:Cis3(gene name synonym)|uniprotkb:Cish3(gene name synonym)|uniprotkb:Socs3(gene name)|psi-mi:Socs3(display_short)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2018)	doi:10.1093/nar/gkx1173|imex:IM-28235|pubmed:29165646	taxid:83332(myctu)|taxid:83332("Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)")	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0471"(MINT)	intact:EBI-25768454|imex:IM-28235-21	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	go:"GO:0004356"(glutamate-ammonia ligase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0006542"(glutamine biosynthetic process)|go:"GO:0046872"(metal ion binding)|go:"GO:0050001"(D-glutaminase activity)|mint:P9WN37|refseq:NP_216738.1|refseq:WP_003411482.1|interpro:IPR008147(Glutamine synthetase, beta-Grasp)|interpro:IPR036651|interpro:IPR014746(Glutamine synthetase/guanido kinase, catalytic region)|interpro:IPR008146(Glutamine synthetase, catalytic region)|interpro:IPR027303	refseq:XP_011247009.1|refseq:NP_031733.1|ensembl:ENSMUSG00000053113(gene)|ensembl:ENSMUST00000054002(transcript)|go:"GO:0001784"(phosphotyrosine residue binding)|go:"GO:0001932"(regulation of protein phosphorylation)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005942"(phosphatidylinositol 3-kinase complex)|go:"GO:0007165"(signal transduction)|go:"GO:0007259"(receptor signaling pathway via JAK-STAT)|go:"GO:0009968"(negative regulation of signal transduction)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0040008"(regulation of growth)|go:"GO:0042532"(negative regulation of tyrosine phosphorylation of STAT protein)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0045595"(regulation of cell differentiation)|go:"GO:0045597"(positive regulation of cell differentiation)|go:"GO:0046426"(negative regulation of receptor signaling pathway via JAK-STAT)|go:"GO:0046627"(negative regulation of insulin receptor signaling pathway)|go:"GO:0046854"(phosphatidylinositol phosphate biosynthetic process)|go:"GO:0046935"(1-phosphatidylinositol-3-kinase regulator activity)|go:"GO:0050728"(negative regulation of inflammatory response)|go:"GO:0060670"(branching involved in labyrinthine layer morphogenesis)|go:"GO:0060674"(placenta blood vessel development)|go:"GO:0060707"(trophoblast giant cell differentiation)|go:"GO:0060708"(spongiotrophoblast differentiation)|go:"GO:1990830"(cellular response to leukemia inhibitory factor)|interpro:IPR000980(SH2 motif)|interpro:IPR001496(SOCS protein, C-terminal)|interpro:IPR028414|interpro:IPR035863|interpro:IPR036036|interpro:IPR036860|mint:O35718|rcsb pdb:2BBU|rcsb pdb:2HMH|rcsb pdb:2JZ3|rcsb pdb:4GL9|reactome:R-MMU-1059683|reactome:R-MMU-877300|reactome:R-MMU-877312|reactome:R-MMU-8849474|reactome:R-MMU-8951664|reactome:R-MMU-909733|reactome:R-MMU-9705462|reactome:R-MMU-983168|dip:DIP-29137N	-	-	-	figure legend:ST5|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2020/07/08	2020/08/14	rogid:LDIpolmw5yhv2iG5+8HKbWlwT8883332	rogid:SFk8FM1xo7SkodsiFXZYzTbLrYg10090	rigid:5IJ02D9k5+IlVvfmOxwUyLDFRlY	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P71619	uniprotkb:O35718	intact:EBI-25767582|uniprotkb:F2GLA0|uniprotkb:I6YAD4	intact:EBI-2659360|uniprotkb:Q3U7X5|uniprotkb:P97803|ensembl:ENSMUSP00000059129	psi-mi:p71619_myctu(display_long)|uniprotkb:ugpB(gene name)|psi-mi:ugpB(display_short)|uniprotkb:Rv2833c(locus name)	psi-mi:socs3_mouse(display_long)|uniprotkb:Cytokine-inducible SH2 protein 3(gene name synonym)|uniprotkb:Protein EF-10(gene name synonym)|uniprotkb:Cis3(gene name synonym)|uniprotkb:Cish3(gene name synonym)|uniprotkb:Socs3(gene name)|psi-mi:Socs3(display_short)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2018)	doi:10.1093/nar/gkx1173|imex:IM-28235|pubmed:29165646	taxid:83332(myctu)|taxid:83332("Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)")	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0471"(MINT)	intact:EBI-25768448|imex:IM-28235-73	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	go:"GO:0005886"(plasma membrane)|rcsb pdb:6R1B|mint:P71619|refseq:NP_217349.1|refseq:WP_003414501.1|interpro:IPR006059(Bacterial extracellular solute-binding, family 1)|interpro:IPR006311(Twin-arginine translocation pathway signal)	refseq:XP_011247009.1|refseq:NP_031733.1|ensembl:ENSMUSG00000053113(gene)|ensembl:ENSMUST00000054002(transcript)|go:"GO:0001784"(phosphotyrosine residue binding)|go:"GO:0001932"(regulation of protein phosphorylation)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005942"(phosphatidylinositol 3-kinase complex)|go:"GO:0007165"(signal transduction)|go:"GO:0007259"(receptor signaling pathway via JAK-STAT)|go:"GO:0009968"(negative regulation of signal transduction)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0040008"(regulation of growth)|go:"GO:0042532"(negative regulation of tyrosine phosphorylation of STAT protein)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0045595"(regulation of cell differentiation)|go:"GO:0045597"(positive regulation of cell differentiation)|go:"GO:0046426"(negative regulation of receptor signaling pathway via JAK-STAT)|go:"GO:0046627"(negative regulation of insulin receptor signaling pathway)|go:"GO:0046854"(phosphatidylinositol phosphate biosynthetic process)|go:"GO:0046935"(1-phosphatidylinositol-3-kinase regulator activity)|go:"GO:0050728"(negative regulation of inflammatory response)|go:"GO:0060670"(branching involved in labyrinthine layer morphogenesis)|go:"GO:0060674"(placenta blood vessel development)|go:"GO:0060707"(trophoblast giant cell differentiation)|go:"GO:0060708"(spongiotrophoblast differentiation)|go:"GO:1990830"(cellular response to leukemia inhibitory factor)|interpro:IPR000980(SH2 motif)|interpro:IPR001496(SOCS protein, C-terminal)|interpro:IPR028414|interpro:IPR035863|interpro:IPR036036|interpro:IPR036860|mint:O35718|rcsb pdb:2BBU|rcsb pdb:2HMH|rcsb pdb:2JZ3|rcsb pdb:4GL9|reactome:R-MMU-1059683|reactome:R-MMU-877300|reactome:R-MMU-877312|reactome:R-MMU-8849474|reactome:R-MMU-8951664|reactome:R-MMU-909733|reactome:R-MMU-9705462|reactome:R-MMU-983168|dip:DIP-29137N	-	-	-	figure legend:ST5|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2020/07/08	2020/08/14	rogid:ldo4FA/3ddzSo1mfnNEPte27F1083332	rogid:SFk8FM1xo7SkodsiFXZYzTbLrYg10090	rigid:Sf7gyc+V61bfjXnKm60OpD6yEjU	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:O69689	uniprotkb:O35718	intact:EBI-25767781|uniprotkb:F2GFU4|uniprotkb:I6Y4D4|uniprotkb:Q7D501	intact:EBI-2659360|uniprotkb:Q3U7X5|uniprotkb:P97803|ensembl:ENSMUSP00000059129	psi-mi:aspat_myctu(display_long)|uniprotkb:Rv3722c(locus name)	psi-mi:socs3_mouse(display_long)|uniprotkb:Cytokine-inducible SH2 protein 3(gene name synonym)|uniprotkb:Protein EF-10(gene name synonym)|uniprotkb:Cis3(gene name synonym)|uniprotkb:Cish3(gene name synonym)|uniprotkb:Socs3(gene name)|psi-mi:Socs3(display_short)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2018)	doi:10.1093/nar/gkx1173|imex:IM-28235|pubmed:29165646	taxid:83332(myctu)|taxid:83332("Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)")	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0471"(MINT)	intact:EBI-25768442|imex:IM-28235-283	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	go:"GO:0004069"("L-aspartate:2-oxoglutarate aminotransferase activity")|go:"GO:0005576"(extracellular region)|rcsb pdb:5C6U|rcsb pdb:6U78|rcsb pdb:6U7A|mint:O69689|refseq:NP_218239.2|refseq:WP_003899653.1|interpro:IPR024551|interpro:IPR015424(Pyridoxal phosphate-dependent transferase, major region)|interpro:IPR015422(Pyridoxal phosphate-dependent transferase, major region, subdomain 2)|interpro:IPR015421(Pyridoxal phosphate-dependent transferase, major region, subdomain 1)	refseq:XP_011247009.1|refseq:NP_031733.1|ensembl:ENSMUSG00000053113(gene)|ensembl:ENSMUST00000054002(transcript)|go:"GO:0001784"(phosphotyrosine residue binding)|go:"GO:0001932"(regulation of protein phosphorylation)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005942"(phosphatidylinositol 3-kinase complex)|go:"GO:0007165"(signal transduction)|go:"GO:0007259"(receptor signaling pathway via JAK-STAT)|go:"GO:0009968"(negative regulation of signal transduction)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0040008"(regulation of growth)|go:"GO:0042532"(negative regulation of tyrosine phosphorylation of STAT protein)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0045595"(regulation of cell differentiation)|go:"GO:0045597"(positive regulation of cell differentiation)|go:"GO:0046426"(negative regulation of receptor signaling pathway via JAK-STAT)|go:"GO:0046627"(negative regulation of insulin receptor signaling pathway)|go:"GO:0046854"(phosphatidylinositol phosphate biosynthetic process)|go:"GO:0046935"(1-phosphatidylinositol-3-kinase regulator activity)|go:"GO:0050728"(negative regulation of inflammatory response)|go:"GO:0060670"(branching involved in labyrinthine layer morphogenesis)|go:"GO:0060674"(placenta blood vessel development)|go:"GO:0060707"(trophoblast giant cell differentiation)|go:"GO:0060708"(spongiotrophoblast differentiation)|go:"GO:1990830"(cellular response to leukemia inhibitory factor)|interpro:IPR000980(SH2 motif)|interpro:IPR001496(SOCS protein, C-terminal)|interpro:IPR028414|interpro:IPR035863|interpro:IPR036036|interpro:IPR036860|mint:O35718|rcsb pdb:2BBU|rcsb pdb:2HMH|rcsb pdb:2JZ3|rcsb pdb:4GL9|reactome:R-MMU-1059683|reactome:R-MMU-877300|reactome:R-MMU-877312|reactome:R-MMU-8849474|reactome:R-MMU-8951664|reactome:R-MMU-909733|reactome:R-MMU-9705462|reactome:R-MMU-983168|dip:DIP-29137N	-	-	-	figure legend:ST5|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2020/07/08	2020/08/14	rogid:TGWnUCrIwLrRrMnna5+/w33GpgA83332	rogid:SFk8FM1xo7SkodsiFXZYzTbLrYg10090	rigid:x8miJga5f51mnlKC1DC2LieqTmI	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:O69689	uniprotkb:Q80U62	intact:EBI-25767781|uniprotkb:F2GFU4|uniprotkb:I6Y4D4|uniprotkb:Q7D501	intact:EBI-3506572|uniprotkb:Q3TAX3|uniprotkb:Q3TD96|uniprotkb:Q3TDF7|uniprotkb:Q3TDU2|uniprotkb:Q6NWW8|uniprotkb:Q6P9T7|uniprotkb:Q6PG18|uniprotkb:Q8BMP7|uniprotkb:Q8BY22|ensembl:ENSMUSP00000087114	psi-mi:aspat_myctu(display_long)|uniprotkb:Rv3722c(locus name)	psi-mi:rubic_mouse(display_long)|uniprotkb:Rubcn(gene name)|psi-mi:Rubcn(display_short)|uniprotkb:Kiaa0226(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2018)	doi:10.1093/nar/gkx1173|imex:IM-28235|pubmed:29165646	taxid:83332(myctu)|taxid:83332("Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)")	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0471"(MINT)	intact:EBI-25768436|imex:IM-28235-155	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	go:"GO:0004069"("L-aspartate:2-oxoglutarate aminotransferase activity")|go:"GO:0005576"(extracellular region)|rcsb pdb:5C6U|rcsb pdb:6U78|rcsb pdb:6U7A|mint:O69689|refseq:NP_218239.2|refseq:WP_003899653.1|interpro:IPR024551|interpro:IPR015424(Pyridoxal phosphate-dependent transferase, major region)|interpro:IPR015422(Pyridoxal phosphate-dependent transferase, major region, subdomain 2)|interpro:IPR015421(Pyridoxal phosphate-dependent transferase, major region, subdomain 1)	refseq:NP_001186967.1|refseq:NP_766203.1|ensembl:ENSMUSG00000035629(gene)|ensembl:ENSMUST00000089684(transcript)|go:"GO:0002376"(immune system process)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005764"(lysosome)|go:"GO:0005769"(early endosome)|go:"GO:0005770"(late endosome)|go:"GO:0005829"(cytosol)|go:"GO:0006897"(endocytosis)|go:"GO:0006914"(autophagy)|go:"GO:0010507"(negative regulation of autophagy)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0043553"(negative regulation of phosphatidylinositol 3-kinase activity)|go:"GO:0045806"(negative regulation of endocytosis)|go:"GO:1901097"(negative regulation of autophagosome maturation)|go:"GO:1901981"(phosphatidylinositol phosphate binding)|interpro:IPR004012(RUN)|interpro:IPR025258|interpro:IPR037213|mint:Q80U62	-	-	-	figure legend:ST5|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2020/07/08	2020/08/14	rogid:TGWnUCrIwLrRrMnna5+/w33GpgA83332	rogid:W9a7lLJWOl9czZuUTzBr+Nfyaqw10090	rigid:tRQFtplpbMyk/aMKwSfue6pHBvE	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P9WHV1	uniprotkb:Q80U62	intact:EBI-25768182|uniprotkb:L0TB68|uniprotkb:P65788|uniprotkb:P71921	intact:EBI-3506572|uniprotkb:Q3TAX3|uniprotkb:Q3TD96|uniprotkb:Q3TDF7|uniprotkb:Q3TDU2|uniprotkb:Q6NWW8|uniprotkb:Q6P9T7|uniprotkb:Q6PG18|uniprotkb:Q8BMP7|uniprotkb:Q8BY22|ensembl:ENSMUSP00000087114	psi-mi:proa_myctu(display_long)|uniprotkb:proA(gene name)|psi-mi:proA(display_short)|uniprotkb:Glutamate-5-semialdehyde dehydrogenase(gene name synonym)|uniprotkb:Glutamyl-gamma-semialdehyde dehydrogenase(gene name synonym)|uniprotkb:MTCY428.20(orf name)|uniprotkb:Rv2427c(locus name)	psi-mi:rubic_mouse(display_long)|uniprotkb:Rubcn(gene name)|psi-mi:Rubcn(display_short)|uniprotkb:Kiaa0226(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2018)	doi:10.1093/nar/gkx1173|imex:IM-28235|pubmed:29165646	taxid:83332(myctu)|taxid:83332("Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)")	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0471"(MINT)	intact:EBI-25768430|imex:IM-28235-71	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	go:"GO:0004350"(glutamate-5-semialdehyde dehydrogenase activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0050661"(NADP binding)|go:"GO:0055129"(L-proline biosynthetic process)|go:"GO:0005829"(cytosol)|mint:P9WHV1|refseq:NP_216943.1|refseq:WP_003412516.1|interpro:IPR016161(Aldehyde/histidinol dehydrogenase)|interpro:IPR016163(Aldehyde dehydrogenase, C-terminal)|interpro:IPR016162(Aldehyde dehydrogenase, N-terminal)|interpro:IPR015590(Aldehyde dehydrogenase)|interpro:IPR020593|interpro:IPR012134(Glutamate-5-semialdehyde dehydrogenase)|interpro:IPR000965(Gamma-glutamyl phosphate reductase GPR)	refseq:NP_001186967.1|refseq:NP_766203.1|ensembl:ENSMUSG00000035629(gene)|ensembl:ENSMUST00000089684(transcript)|go:"GO:0002376"(immune system process)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005764"(lysosome)|go:"GO:0005769"(early endosome)|go:"GO:0005770"(late endosome)|go:"GO:0005829"(cytosol)|go:"GO:0006897"(endocytosis)|go:"GO:0006914"(autophagy)|go:"GO:0010507"(negative regulation of autophagy)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0043553"(negative regulation of phosphatidylinositol 3-kinase activity)|go:"GO:0045806"(negative regulation of endocytosis)|go:"GO:1901097"(negative regulation of autophagosome maturation)|go:"GO:1901981"(phosphatidylinositol phosphate binding)|interpro:IPR004012(RUN)|interpro:IPR025258|interpro:IPR037213|mint:Q80U62	-	-	-	figure legend:ST5|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2020/07/08	2020/08/14	rogid:fzCkUX2wrGj0ZK0LOaeT+UNWpwI83332	rogid:W9a7lLJWOl9czZuUTzBr+Nfyaqw10090	rigid:q6AXIBLUt9qIeQC28VWWk/luhbI	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:O53319	uniprotkb:Q80U62	intact:EBI-25767766|uniprotkb:I6X6K2|uniprotkb:L0TEH7	intact:EBI-3506572|uniprotkb:Q3TAX3|uniprotkb:Q3TD96|uniprotkb:Q3TDF7|uniprotkb:Q3TDU2|uniprotkb:Q6NWW8|uniprotkb:Q6P9T7|uniprotkb:Q6PG18|uniprotkb:Q8BMP7|uniprotkb:Q8BY22|ensembl:ENSMUSP00000087114	psi-mi:o53319_myctu(display_long)|uniprotkb:Rv3169(locus name)	psi-mi:rubic_mouse(display_long)|uniprotkb:Rubcn(gene name)|psi-mi:Rubcn(display_short)|uniprotkb:Kiaa0226(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2018)	doi:10.1093/nar/gkx1173|imex:IM-28235|pubmed:29165646	taxid:83332(myctu)|taxid:83332("Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)")	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0471"(MINT)	intact:EBI-25768424|imex:IM-28235-153	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	go:"GO:0005886"(plasma membrane)|mint:O53319|refseq:NP_217685.1|refseq:WP_003416605.1	refseq:NP_001186967.1|refseq:NP_766203.1|ensembl:ENSMUSG00000035629(gene)|ensembl:ENSMUST00000089684(transcript)|go:"GO:0002376"(immune system process)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005764"(lysosome)|go:"GO:0005769"(early endosome)|go:"GO:0005770"(late endosome)|go:"GO:0005829"(cytosol)|go:"GO:0006897"(endocytosis)|go:"GO:0006914"(autophagy)|go:"GO:0010507"(negative regulation of autophagy)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0043553"(negative regulation of phosphatidylinositol 3-kinase activity)|go:"GO:0045806"(negative regulation of endocytosis)|go:"GO:1901097"(negative regulation of autophagosome maturation)|go:"GO:1901981"(phosphatidylinositol phosphate binding)|interpro:IPR004012(RUN)|interpro:IPR025258|interpro:IPR037213|mint:Q80U62	-	-	-	figure legend:ST5|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2020/07/08	2020/08/14	rogid:Gd1O5B5qTAQflXzn9MR+6fgqvDs83332	rogid:W9a7lLJWOl9czZuUTzBr+Nfyaqw10090	rigid:WkfhSWfVvxx1RP7AsFSS81IwLHY	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:O50440	uniprotkb:Q80U62	intact:EBI-25767742|uniprotkb:I6XXB2|uniprotkb:L0T7J5	intact:EBI-3506572|uniprotkb:Q3TAX3|uniprotkb:Q3TD96|uniprotkb:Q3TDF7|uniprotkb:Q3TDU2|uniprotkb:Q6NWW8|uniprotkb:Q6P9T7|uniprotkb:Q6PG18|uniprotkb:Q8BMP7|uniprotkb:Q8BY22|ensembl:ENSMUSP00000087114	psi-mi:chp2_myctu(display_long)|uniprotkb:chp2(gene name)|psi-mi:chp2(display_short)|uniprotkb:LH57_06500(orf name)|uniprotkb:P425_01234(orf name)|uniprotkb:Rv1184c(locus name)|uniprotkb:RVBD_1184c(locus name)	psi-mi:rubic_mouse(display_long)|uniprotkb:Rubcn(gene name)|psi-mi:Rubcn(display_short)|uniprotkb:Kiaa0226(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2018)	doi:10.1093/nar/gkx1173|imex:IM-28235|pubmed:29165646	taxid:83332(myctu)|taxid:83332("Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)")	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0471"(MINT)	intact:EBI-25768418|imex:IM-28235-151	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	go:"GO:0005886"(plasma membrane)|go:"GO:0006629"(lipid metabolic process)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016746"(acyltransferase activity)|go:"GO:0005618"(cell wall)|mint:O50440|refseq:NP_215700.1|refseq:WP_003406195.1|interpro:IPR013228(PE-PPE, C-terminal)	refseq:NP_001186967.1|refseq:NP_766203.1|ensembl:ENSMUSG00000035629(gene)|ensembl:ENSMUST00000089684(transcript)|go:"GO:0002376"(immune system process)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005764"(lysosome)|go:"GO:0005769"(early endosome)|go:"GO:0005770"(late endosome)|go:"GO:0005829"(cytosol)|go:"GO:0006897"(endocytosis)|go:"GO:0006914"(autophagy)|go:"GO:0010507"(negative regulation of autophagy)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0043553"(negative regulation of phosphatidylinositol 3-kinase activity)|go:"GO:0045806"(negative regulation of endocytosis)|go:"GO:1901097"(negative regulation of autophagosome maturation)|go:"GO:1901981"(phosphatidylinositol phosphate binding)|interpro:IPR004012(RUN)|interpro:IPR025258|interpro:IPR037213|mint:Q80U62	-	-	-	figure legend:ST5|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2020/07/08	2020/08/14	rogid:IXzYfb7UxFgqBXPZ6NZHLy3hdTc83332	rogid:W9a7lLJWOl9czZuUTzBr+Nfyaqw10090	rigid:FmAFX33F7JBMwOhEBKFj7SAkoUM	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:I6YC03	uniprotkb:Q80U62	intact:EBI-25768074	intact:EBI-3506572|uniprotkb:Q3TAX3|uniprotkb:Q3TD96|uniprotkb:Q3TDF7|uniprotkb:Q3TDU2|uniprotkb:Q6NWW8|uniprotkb:Q6P9T7|uniprotkb:Q6PG18|uniprotkb:Q8BMP7|uniprotkb:Q8BY22|ensembl:ENSMUSP00000087114	psi-mi:ephb_myctu(display_long)|uniprotkb:ephB(gene name)|psi-mi:ephB(display_short)|uniprotkb:Epoxide hydrolase EphB(gene name synonym)|uniprotkb:LH57_10545(orf name)|uniprotkb:Rv1938(locus name)	psi-mi:rubic_mouse(display_long)|uniprotkb:Rubcn(gene name)|psi-mi:Rubcn(display_short)|uniprotkb:Kiaa0226(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2018)	doi:10.1093/nar/gkx1173|imex:IM-28235|pubmed:29165646	taxid:83332(myctu)|taxid:83332("Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)")	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0471"(MINT)	intact:EBI-25768412|imex:IM-28235-69	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	go:"GO:0009636"(response to toxic substance)|go:"GO:0016787"(hydrolase activity)|go:"GO:0018742"(epoxide hydrolase B activity)|go:"GO:0042803"(protein homodimerization activity)|mint:I6YC03|refseq:NP_216454.1|refseq:WP_003899091.1|interpro:IPR029058|interpro:IPR000073(Alpha/beta hydrolase fold-1)|interpro:IPR000639(Epoxide hydrolase-like)	refseq:NP_001186967.1|refseq:NP_766203.1|ensembl:ENSMUSG00000035629(gene)|ensembl:ENSMUST00000089684(transcript)|go:"GO:0002376"(immune system process)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005764"(lysosome)|go:"GO:0005769"(early endosome)|go:"GO:0005770"(late endosome)|go:"GO:0005829"(cytosol)|go:"GO:0006897"(endocytosis)|go:"GO:0006914"(autophagy)|go:"GO:0010507"(negative regulation of autophagy)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0043553"(negative regulation of phosphatidylinositol 3-kinase activity)|go:"GO:0045806"(negative regulation of endocytosis)|go:"GO:1901097"(negative regulation of autophagosome maturation)|go:"GO:1901981"(phosphatidylinositol phosphate binding)|interpro:IPR004012(RUN)|interpro:IPR025258|interpro:IPR037213|mint:Q80U62	-	-	-	figure legend:ST5|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2020/07/08	2020/08/14	rogid:sRxqN+k+jfx7zSE+ctNP+i+id0I83332	rogid:W9a7lLJWOl9czZuUTzBr+Nfyaqw10090	rigid:OPu+xruMCquX95VgFeJBfLqN0IQ	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P9WHT9	uniprotkb:Q80U62	intact:EBI-7947958|uniprotkb:O33245|intact:MINT-7985947|uniprotkb:Q7D7I2|uniprotkb:L0T8V8	intact:EBI-3506572|uniprotkb:Q3TAX3|uniprotkb:Q3TD96|uniprotkb:Q3TDF7|uniprotkb:Q3TDU2|uniprotkb:Q6NWW8|uniprotkb:Q6P9T7|uniprotkb:Q6PG18|uniprotkb:Q8BMP7|uniprotkb:Q8BY22|ensembl:ENSMUSP00000087114	psi-mi:psb_myctu(display_long)|uniprotkb:Proteasome core protein PrcB(gene name synonym)|uniprotkb:Rv2110c(locus name)|uniprotkb:prcB(gene name)|psi-mi:prcB(display_short)|uniprotkb:20S proteasome beta subunit(gene name synonym)	psi-mi:rubic_mouse(display_long)|uniprotkb:Rubcn(gene name)|psi-mi:Rubcn(display_short)|uniprotkb:Kiaa0226(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2018)	doi:10.1093/nar/gkx1173|imex:IM-28235|pubmed:29165646	taxid:83332(myctu)|taxid:83332("Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)")	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0471"(MINT)	intact:EBI-25768406|imex:IM-28235-325	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	interpro:IPR029055|refseq:WP_003411023.1|interpro:IPR001353(20S proteasome, A and B subunits)|refseq:NP_216626.1|interpro:IPR023333|interpro:IPR022483|mint:P9WHT9|go:"GO:0004298"(threonine-type endopeptidase activity)|go:"GO:0005576"(extracellular region)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0010498"(proteasomal protein catabolic process)|go:"GO:0019773"(proteasome core complex, alpha-subunit complex)|go:"GO:0019774"(proteasome core complex, beta-subunit complex)|go:"GO:0019941"(modification-dependent protein catabolic process)|go:"GO:0030682"(mitigation of host defenses by symbiont)|go:"GO:0035375"(zymogen binding)|go:"GO:0051603"(proteolysis involved in cellular protein catabolic process)|rcsb pdb:2FHG|rcsb pdb:2FHH|rcsb pdb:2JAY|rcsb pdb:3H6F|rcsb pdb:3H6I|rcsb pdb:3HF9|rcsb pdb:3HFA|rcsb pdb:3KRD|rcsb pdb:3MFE|rcsb pdb:3MI0|rcsb pdb:3MKA|rcsb pdb:5LZP|rcsb pdb:5THO|rcsb pdb:5TRG|rcsb pdb:5TRR|rcsb pdb:5TRS|rcsb pdb:5TRY|rcsb pdb:5TS0|rcsb pdb:6BGL|rcsb pdb:6BGO|rcsb pdb:6OCW|rcsb pdb:6OCZ|rcsb pdb:6ODE	refseq:NP_001186967.1|refseq:NP_766203.1|ensembl:ENSMUSG00000035629(gene)|ensembl:ENSMUST00000089684(transcript)|go:"GO:0002376"(immune system process)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005764"(lysosome)|go:"GO:0005769"(early endosome)|go:"GO:0005770"(late endosome)|go:"GO:0005829"(cytosol)|go:"GO:0006897"(endocytosis)|go:"GO:0006914"(autophagy)|go:"GO:0010507"(negative regulation of autophagy)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0043553"(negative regulation of phosphatidylinositol 3-kinase activity)|go:"GO:0045806"(negative regulation of endocytosis)|go:"GO:1901097"(negative regulation of autophagosome maturation)|go:"GO:1901981"(phosphatidylinositol phosphate binding)|interpro:IPR004012(RUN)|interpro:IPR025258|interpro:IPR037213|mint:Q80U62	-	crc64:3FC3FCD81231E129|comment:mint	-	figure legend:ST5|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2020/07/08	2020/08/14	rogid:hQ8Eci/BIL/quaWNhklTdFRPHDI83332	rogid:W9a7lLJWOl9czZuUTzBr+Nfyaqw10090	rigid:IdT1BqMoiCxMr3V8X5Xw78tQx8Q	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:O53850	uniprotkb:Q80U62	intact:EBI-25768148|uniprotkb:F2GJ15|uniprotkb:I6XWE0	intact:EBI-3506572|uniprotkb:Q3TAX3|uniprotkb:Q3TD96|uniprotkb:Q3TDF7|uniprotkb:Q3TDU2|uniprotkb:Q6NWW8|uniprotkb:Q6P9T7|uniprotkb:Q6PG18|uniprotkb:Q8BMP7|uniprotkb:Q8BY22|ensembl:ENSMUSP00000087114	psi-mi:o53850_myctu(display_long)|uniprotkb:lpqR(gene name)|psi-mi:lpqR(display_short)|uniprotkb:Rv0838(locus name)	psi-mi:rubic_mouse(display_long)|uniprotkb:Rubcn(gene name)|psi-mi:Rubcn(display_short)|uniprotkb:Kiaa0226(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2018)	doi:10.1093/nar/gkx1173|imex:IM-28235|pubmed:29165646	taxid:83332(myctu)|taxid:83332("Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)")	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0471"(MINT)	intact:EBI-25768400|imex:IM-28235-19	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	go:"GO:0005576"(extracellular region)|go:"GO:0008237"(metallopeptidase activity)|go:"GO:0008270"(zinc ion binding)|go:"GO:0016805"(dipeptidase activity)|go:"GO:0071555"(cell wall organization)|mint:O53850|refseq:NP_215353.1|refseq:WP_003898609.1|interpro:IPR000755(Peptidase M15D, vanX D-ala-D-ala dipeptidase)|interpro:IPR009045(Hedgehog/DD-peptidase, zinc-binding motif)	refseq:NP_001186967.1|refseq:NP_766203.1|ensembl:ENSMUSG00000035629(gene)|ensembl:ENSMUST00000089684(transcript)|go:"GO:0002376"(immune system process)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005764"(lysosome)|go:"GO:0005769"(early endosome)|go:"GO:0005770"(late endosome)|go:"GO:0005829"(cytosol)|go:"GO:0006897"(endocytosis)|go:"GO:0006914"(autophagy)|go:"GO:0010507"(negative regulation of autophagy)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0043553"(negative regulation of phosphatidylinositol 3-kinase activity)|go:"GO:0045806"(negative regulation of endocytosis)|go:"GO:1901097"(negative regulation of autophagosome maturation)|go:"GO:1901981"(phosphatidylinositol phosphate binding)|interpro:IPR004012(RUN)|interpro:IPR025258|interpro:IPR037213|mint:Q80U62	-	-	-	figure legend:ST5|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2020/07/08	2020/08/14	rogid:40KIrYcfAW5IBFq1Hx5FLVOcLf483332	rogid:W9a7lLJWOl9czZuUTzBr+Nfyaqw10090	rigid:PNU2p2TsKVkh69iGU4Qo1FOFT+0	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:I6Y946	uniprotkb:Q80U62	intact:EBI-25767727	intact:EBI-3506572|uniprotkb:Q3TAX3|uniprotkb:Q3TD96|uniprotkb:Q3TDF7|uniprotkb:Q3TDU2|uniprotkb:Q6NWW8|uniprotkb:Q6P9T7|uniprotkb:Q6PG18|uniprotkb:Q8BMP7|uniprotkb:Q8BY22|ensembl:ENSMUSP00000087114	psi-mi:i6y946_myctu(display_long)|uniprotkb:Rv0925c(locus name)	psi-mi:rubic_mouse(display_long)|uniprotkb:Rubcn(gene name)|psi-mi:Rubcn(display_short)|uniprotkb:Kiaa0226(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2018)	doi:10.1093/nar/gkx1173|imex:IM-28235|pubmed:29165646	taxid:83332(myctu)|taxid:83332("Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)")	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0471"(MINT)	intact:EBI-25768394|imex:IM-28235-17	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	go:"GO:0016491"(oxidoreductase activity)|mint:I6Y946|refseq:NP_215440.1|refseq:WP_003404764.1|interpro:IPR029039|interpro:IPR005025(NADPH-dependent FMN reductase)	refseq:NP_001186967.1|refseq:NP_766203.1|ensembl:ENSMUSG00000035629(gene)|ensembl:ENSMUST00000089684(transcript)|go:"GO:0002376"(immune system process)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005764"(lysosome)|go:"GO:0005769"(early endosome)|go:"GO:0005770"(late endosome)|go:"GO:0005829"(cytosol)|go:"GO:0006897"(endocytosis)|go:"GO:0006914"(autophagy)|go:"GO:0010507"(negative regulation of autophagy)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0043553"(negative regulation of phosphatidylinositol 3-kinase activity)|go:"GO:0045806"(negative regulation of endocytosis)|go:"GO:1901097"(negative regulation of autophagosome maturation)|go:"GO:1901981"(phosphatidylinositol phosphate binding)|interpro:IPR004012(RUN)|interpro:IPR025258|interpro:IPR037213|mint:Q80U62	-	-	-	figure legend:ST5|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2020/07/08	2020/08/14	rogid:JOW06LtizimdrjJdMmMnM9ru8n083332	rogid:W9a7lLJWOl9czZuUTzBr+Nfyaqw10090	rigid:AHZgbYM4OWCfH27qL4AtU/M2n14	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P9WP17	uniprotkb:Q80U62	intact:EBI-25767691|uniprotkb:L0T3B0|uniprotkb:O07247	intact:EBI-3506572|uniprotkb:Q3TAX3|uniprotkb:Q3TD96|uniprotkb:Q3TDF7|uniprotkb:Q3TDU2|uniprotkb:Q6NWW8|uniprotkb:Q6P9T7|uniprotkb:Q6PG18|uniprotkb:Q8BMP7|uniprotkb:Q8BY22|ensembl:ENSMUSP00000087114	psi-mi:dcdb_myctu(display_long)|uniprotkb:dcd(gene name)|psi-mi:dcd(display_short)|uniprotkb:"Bifunctional dCTP deaminase:dUTPase"(gene name synonym)|uniprotkb:DCD-DUT(gene name synonym)|uniprotkb:MTCY63.26(orf name)|uniprotkb:Rv0321(locus name)	psi-mi:rubic_mouse(display_long)|uniprotkb:Rubcn(gene name)|psi-mi:Rubcn(display_short)|uniprotkb:Kiaa0226(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2018)	doi:10.1093/nar/gkx1173|imex:IM-28235|pubmed:29165646	taxid:83332(myctu)|taxid:83332("Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)")	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0471"(MINT)	intact:EBI-25768388|imex:IM-28235-245	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	go:"GO:0000166"(nucleotide binding)|go:"GO:0004170"(dUTP diphosphatase activity)|go:"GO:0006226"(dUMP biosynthetic process)|go:"GO:0006229"(dUTP biosynthetic process)|go:"GO:0008829"(dCTP deaminase activity)|go:"GO:0015949"(nucleobase-containing small molecule interconversion)|go:"GO:0033973"("dCTP deaminase (dUMP-forming) activity")|rcsb pdb:2QLP|rcsb pdb:2QXX|rcsb pdb:4A6A|mint:P9WP17|refseq:NP_214835.1|refseq:WP_003898399.1|interpro:IPR011962(Deoxycytidine triphosphate deaminase)|interpro:IPR029054|interpro:IPR036157|interpro:IPR033704	refseq:NP_001186967.1|refseq:NP_766203.1|ensembl:ENSMUSG00000035629(gene)|ensembl:ENSMUST00000089684(transcript)|go:"GO:0002376"(immune system process)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005764"(lysosome)|go:"GO:0005769"(early endosome)|go:"GO:0005770"(late endosome)|go:"GO:0005829"(cytosol)|go:"GO:0006897"(endocytosis)|go:"GO:0006914"(autophagy)|go:"GO:0010507"(negative regulation of autophagy)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0043553"(negative regulation of phosphatidylinositol 3-kinase activity)|go:"GO:0045806"(negative regulation of endocytosis)|go:"GO:1901097"(negative regulation of autophagosome maturation)|go:"GO:1901981"(phosphatidylinositol phosphate binding)|interpro:IPR004012(RUN)|interpro:IPR025258|interpro:IPR037213|mint:Q80U62	-	-	-	figure legend:ST5|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2020/07/08	2020/08/14	rogid:7Llq0DbdMabIKeH06jyXlfJfD3083332	rogid:W9a7lLJWOl9czZuUTzBr+Nfyaqw10090	rigid:3064P8apL+IQo51ydvyjK92cVZk	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:O53319	uniprotkb:Q60803	intact:EBI-25767766|uniprotkb:I6X6K2|uniprotkb:L0TEH7	intact:EBI-520135|uniprotkb:B2RPW3|uniprotkb:Q62380|ensembl:ENSMUSP00000021706	psi-mi:o53319_myctu(display_long)|uniprotkb:Rv3169(locus name)	psi-mi:traf3_mouse(display_long)|uniprotkb:CD40 receptor-associated factor 1(gene name synonym)|uniprotkb:TRAFAMN(gene name synonym)|uniprotkb:Traf3(gene name)|psi-mi:Traf3(display_short)|uniprotkb:Craf1(gene name synonym)|uniprotkb:Trafamn(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase TRAF3(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2018)	doi:10.1093/nar/gkx1173|imex:IM-28235|pubmed:29165646	taxid:83332(myctu)|taxid:83332("Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)")	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0471"(MINT)	intact:EBI-25768580|imex:IM-28235-329	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	go:"GO:0005886"(plasma membrane)|mint:O53319|refseq:NP_217685.1|refseq:WP_003416605.1	refseq:NP_035762.2|ensembl:ENSMUSG00000021277(gene)|ensembl:ENSMUST00000021706(transcript)|go:"GO:0001817"(regulation of cytokine production)|go:"GO:0002224"(toll-like receptor signaling pathway)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005164"(tumor necrosis factor receptor binding)|go:"GO:0005768"(endosome)|go:"GO:0006915"(apoptotic process)|go:"GO:0008063"(Toll signaling pathway)|go:"GO:0008270"(zinc ion binding)|go:"GO:0009898"(cytoplasmic side of plasma membrane)|go:"GO:0019901"(protein kinase binding)|go:"GO:0019903"(protein phosphatase binding)|go:"GO:0030162"(regulation of proteolysis)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0031996"(thioesterase binding)|go:"GO:0032088"(negative regulation of NF-kappaB transcription factor activity)|go:"GO:0032648"(regulation of interferon-beta production)|go:"GO:0033209"(tumor necrosis factor-mediated signaling pathway)|go:"GO:0035631"(CD40 receptor complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0043122"(regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0045087"(innate immune response)|go:"GO:0046330"(positive regulation of JNK cascade)|go:"GO:0050688"(regulation of defense response to virus)|go:"GO:0070534"(protein K63-linked ubiquitination)|interpro:IPR001293(Zinc finger, TRAF-type)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR002083(MATH)|interpro:IPR008974(TRAF-like)|interpro:IPR012227(TNF receptor-associated factor TRAF)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017907|interpro:IPR027128|interpro:IPR037304|interpro:IPR043211|mint:Q60803|rcsb pdb:4GHU|reactome:R-MMU-5668541|reactome:R-MMU-5676594|reactome:R-MMU-5689896|reactome:R-MMU-936964|refseq:XP_006515861.1|refseq:XP_006515862.1|refseq:XP_006515863.1|refseq:XP_006515864.1|dip:DIP-34050N	-	-	-	figure legend:ST5|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2020/07/08	2020/08/14	rogid:Gd1O5B5qTAQflXzn9MR+6fgqvDs83332	rogid:2MrUSSGdyGB3zrZ39xovGDK6ysE10090	rigid:5zQ1SlFDxX+F+RL1bmSBUy+wAUs	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:O50440	uniprotkb:Q60803	intact:EBI-25767742|uniprotkb:I6XXB2|uniprotkb:L0T7J5	intact:EBI-520135|uniprotkb:B2RPW3|uniprotkb:Q62380|ensembl:ENSMUSP00000021706	psi-mi:chp2_myctu(display_long)|uniprotkb:chp2(gene name)|psi-mi:chp2(display_short)|uniprotkb:LH57_06500(orf name)|uniprotkb:P425_01234(orf name)|uniprotkb:Rv1184c(locus name)|uniprotkb:RVBD_1184c(locus name)	psi-mi:traf3_mouse(display_long)|uniprotkb:CD40 receptor-associated factor 1(gene name synonym)|uniprotkb:TRAFAMN(gene name synonym)|uniprotkb:Traf3(gene name)|psi-mi:Traf3(display_short)|uniprotkb:Craf1(gene name synonym)|uniprotkb:Trafamn(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase TRAF3(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2018)	doi:10.1093/nar/gkx1173|imex:IM-28235|pubmed:29165646	taxid:83332(myctu)|taxid:83332("Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)")	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0471"(MINT)	intact:EBI-25768574|imex:IM-28235-79	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	go:"GO:0005886"(plasma membrane)|go:"GO:0006629"(lipid metabolic process)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016746"(acyltransferase activity)|go:"GO:0005618"(cell wall)|mint:O50440|refseq:NP_215700.1|refseq:WP_003406195.1|interpro:IPR013228(PE-PPE, C-terminal)	refseq:NP_035762.2|ensembl:ENSMUSG00000021277(gene)|ensembl:ENSMUST00000021706(transcript)|go:"GO:0001817"(regulation of cytokine production)|go:"GO:0002224"(toll-like receptor signaling pathway)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005164"(tumor necrosis factor receptor binding)|go:"GO:0005768"(endosome)|go:"GO:0006915"(apoptotic process)|go:"GO:0008063"(Toll signaling pathway)|go:"GO:0008270"(zinc ion binding)|go:"GO:0009898"(cytoplasmic side of plasma membrane)|go:"GO:0019901"(protein kinase binding)|go:"GO:0019903"(protein phosphatase binding)|go:"GO:0030162"(regulation of proteolysis)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0031996"(thioesterase binding)|go:"GO:0032088"(negative regulation of NF-kappaB transcription factor activity)|go:"GO:0032648"(regulation of interferon-beta production)|go:"GO:0033209"(tumor necrosis factor-mediated signaling pathway)|go:"GO:0035631"(CD40 receptor complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0043122"(regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0045087"(innate immune response)|go:"GO:0046330"(positive regulation of JNK cascade)|go:"GO:0050688"(regulation of defense response to virus)|go:"GO:0070534"(protein K63-linked ubiquitination)|interpro:IPR001293(Zinc finger, TRAF-type)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR002083(MATH)|interpro:IPR008974(TRAF-like)|interpro:IPR012227(TNF receptor-associated factor TRAF)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017907|interpro:IPR027128|interpro:IPR037304|interpro:IPR043211|mint:Q60803|rcsb pdb:4GHU|reactome:R-MMU-5668541|reactome:R-MMU-5676594|reactome:R-MMU-5689896|reactome:R-MMU-936964|refseq:XP_006515861.1|refseq:XP_006515862.1|refseq:XP_006515863.1|refseq:XP_006515864.1|dip:DIP-34050N	-	-	-	figure legend:ST5|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2020/07/08	2020/08/14	rogid:IXzYfb7UxFgqBXPZ6NZHLy3hdTc83332	rogid:2MrUSSGdyGB3zrZ39xovGDK6ysE10090	rigid:DJI4Ywqd3y6q741P8Ty3dluHMRI	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:O53850	uniprotkb:Q60803	intact:EBI-25768148|uniprotkb:F2GJ15|uniprotkb:I6XWE0	intact:EBI-520135|uniprotkb:B2RPW3|uniprotkb:Q62380|ensembl:ENSMUSP00000021706	psi-mi:o53850_myctu(display_long)|uniprotkb:lpqR(gene name)|psi-mi:lpqR(display_short)|uniprotkb:Rv0838(locus name)	psi-mi:traf3_mouse(display_long)|uniprotkb:CD40 receptor-associated factor 1(gene name synonym)|uniprotkb:TRAFAMN(gene name synonym)|uniprotkb:Traf3(gene name)|psi-mi:Traf3(display_short)|uniprotkb:Craf1(gene name synonym)|uniprotkb:Trafamn(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase TRAF3(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2018)	doi:10.1093/nar/gkx1173|imex:IM-28235|pubmed:29165646	taxid:83332(myctu)|taxid:83332("Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)")	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0471"(MINT)	intact:EBI-25768568|imex:IM-28235-207	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	go:"GO:0005576"(extracellular region)|go:"GO:0008237"(metallopeptidase activity)|go:"GO:0008270"(zinc ion binding)|go:"GO:0016805"(dipeptidase activity)|go:"GO:0071555"(cell wall organization)|mint:O53850|refseq:NP_215353.1|refseq:WP_003898609.1|interpro:IPR000755(Peptidase M15D, vanX D-ala-D-ala dipeptidase)|interpro:IPR009045(Hedgehog/DD-peptidase, zinc-binding motif)	refseq:NP_035762.2|ensembl:ENSMUSG00000021277(gene)|ensembl:ENSMUST00000021706(transcript)|go:"GO:0001817"(regulation of cytokine production)|go:"GO:0002224"(toll-like receptor signaling pathway)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005164"(tumor necrosis factor receptor binding)|go:"GO:0005768"(endosome)|go:"GO:0006915"(apoptotic process)|go:"GO:0008063"(Toll signaling pathway)|go:"GO:0008270"(zinc ion binding)|go:"GO:0009898"(cytoplasmic side of plasma membrane)|go:"GO:0019901"(protein kinase binding)|go:"GO:0019903"(protein phosphatase binding)|go:"GO:0030162"(regulation of proteolysis)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0031996"(thioesterase binding)|go:"GO:0032088"(negative regulation of NF-kappaB transcription factor activity)|go:"GO:0032648"(regulation of interferon-beta production)|go:"GO:0033209"(tumor necrosis factor-mediated signaling pathway)|go:"GO:0035631"(CD40 receptor complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0043122"(regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0045087"(innate immune response)|go:"GO:0046330"(positive regulation of JNK cascade)|go:"GO:0050688"(regulation of defense response to virus)|go:"GO:0070534"(protein K63-linked ubiquitination)|interpro:IPR001293(Zinc finger, TRAF-type)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR002083(MATH)|interpro:IPR008974(TRAF-like)|interpro:IPR012227(TNF receptor-associated factor TRAF)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017907|interpro:IPR027128|interpro:IPR037304|interpro:IPR043211|mint:Q60803|rcsb pdb:4GHU|reactome:R-MMU-5668541|reactome:R-MMU-5676594|reactome:R-MMU-5689896|reactome:R-MMU-936964|refseq:XP_006515861.1|refseq:XP_006515862.1|refseq:XP_006515863.1|refseq:XP_006515864.1|dip:DIP-34050N	-	-	-	figure legend:ST5|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2020/07/08	2020/08/14	rogid:40KIrYcfAW5IBFq1Hx5FLVOcLf483332	rogid:2MrUSSGdyGB3zrZ39xovGDK6ysE10090	rigid:A6OuIP5R1YTruYKflbUMjh7+ENw	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P9WP17	uniprotkb:Q60803	intact:EBI-25767691|uniprotkb:L0T3B0|uniprotkb:O07247	intact:EBI-520135|uniprotkb:B2RPW3|uniprotkb:Q62380|ensembl:ENSMUSP00000021706	psi-mi:dcdb_myctu(display_long)|uniprotkb:dcd(gene name)|psi-mi:dcd(display_short)|uniprotkb:"Bifunctional dCTP deaminase:dUTPase"(gene name synonym)|uniprotkb:DCD-DUT(gene name synonym)|uniprotkb:MTCY63.26(orf name)|uniprotkb:Rv0321(locus name)	psi-mi:traf3_mouse(display_long)|uniprotkb:CD40 receptor-associated factor 1(gene name synonym)|uniprotkb:TRAFAMN(gene name synonym)|uniprotkb:Traf3(gene name)|psi-mi:Traf3(display_short)|uniprotkb:Craf1(gene name synonym)|uniprotkb:Trafamn(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase TRAF3(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2018)	doi:10.1093/nar/gkx1173|imex:IM-28235|pubmed:29165646	taxid:83332(myctu)|taxid:83332("Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)")	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0471"(MINT)	intact:EBI-25768562|imex:IM-28235-247	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	go:"GO:0000166"(nucleotide binding)|go:"GO:0004170"(dUTP diphosphatase activity)|go:"GO:0006226"(dUMP biosynthetic process)|go:"GO:0006229"(dUTP biosynthetic process)|go:"GO:0008829"(dCTP deaminase activity)|go:"GO:0015949"(nucleobase-containing small molecule interconversion)|go:"GO:0033973"("dCTP deaminase (dUMP-forming) activity")|rcsb pdb:2QLP|rcsb pdb:2QXX|rcsb pdb:4A6A|mint:P9WP17|refseq:NP_214835.1|refseq:WP_003898399.1|interpro:IPR011962(Deoxycytidine triphosphate deaminase)|interpro:IPR029054|interpro:IPR036157|interpro:IPR033704	refseq:NP_035762.2|ensembl:ENSMUSG00000021277(gene)|ensembl:ENSMUST00000021706(transcript)|go:"GO:0001817"(regulation of cytokine production)|go:"GO:0002224"(toll-like receptor signaling pathway)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005164"(tumor necrosis factor receptor binding)|go:"GO:0005768"(endosome)|go:"GO:0006915"(apoptotic process)|go:"GO:0008063"(Toll signaling pathway)|go:"GO:0008270"(zinc ion binding)|go:"GO:0009898"(cytoplasmic side of plasma membrane)|go:"GO:0019901"(protein kinase binding)|go:"GO:0019903"(protein phosphatase binding)|go:"GO:0030162"(regulation of proteolysis)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0031996"(thioesterase binding)|go:"GO:0032088"(negative regulation of NF-kappaB transcription factor activity)|go:"GO:0032648"(regulation of interferon-beta production)|go:"GO:0033209"(tumor necrosis factor-mediated signaling pathway)|go:"GO:0035631"(CD40 receptor complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0043122"(regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0045087"(innate immune response)|go:"GO:0046330"(positive regulation of JNK cascade)|go:"GO:0050688"(regulation of defense response to virus)|go:"GO:0070534"(protein K63-linked ubiquitination)|interpro:IPR001293(Zinc finger, TRAF-type)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR002083(MATH)|interpro:IPR008974(TRAF-like)|interpro:IPR012227(TNF receptor-associated factor TRAF)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017907|interpro:IPR027128|interpro:IPR037304|interpro:IPR043211|mint:Q60803|rcsb pdb:4GHU|reactome:R-MMU-5668541|reactome:R-MMU-5676594|reactome:R-MMU-5689896|reactome:R-MMU-936964|refseq:XP_006515861.1|refseq:XP_006515862.1|refseq:XP_006515863.1|refseq:XP_006515864.1|dip:DIP-34050N	-	-	-	figure legend:ST5|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2020/07/08	2020/08/14	rogid:7Llq0DbdMabIKeH06jyXlfJfD3083332	rogid:2MrUSSGdyGB3zrZ39xovGDK6ysE10090	rigid:x8OWVGZSvEKYejwMwf7dHuskRk4	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P9WJB9	uniprotkb:Q60803	intact:EBI-25767670|uniprotkb:L0TE21|uniprotkb:O69744|uniprotkb:Q7D4P0	intact:EBI-520135|uniprotkb:B2RPW3|uniprotkb:Q62380|ensembl:ENSMUSP00000021706	psi-mi:espl_myctu(display_long)|uniprotkb:espL(gene name)|psi-mi:espL(display_short)|uniprotkb:Rv3880c(locus name)	psi-mi:traf3_mouse(display_long)|uniprotkb:CD40 receptor-associated factor 1(gene name synonym)|uniprotkb:TRAFAMN(gene name synonym)|uniprotkb:Traf3(gene name)|psi-mi:Traf3(display_short)|uniprotkb:Craf1(gene name synonym)|uniprotkb:Trafamn(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase TRAF3(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2018)	doi:10.1093/nar/gkx1173|imex:IM-28235|pubmed:29165646	taxid:83332(myctu)|taxid:83332("Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)")	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0471"(MINT)	intact:EBI-25768556|imex:IM-28235-109	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	go:"GO:0003677"(DNA binding)|go:"GO:0005618"(cell wall)|go:"GO:0005886"(plasma membrane)|go:"GO:0052170"(suppression by symbiont of host innate immune response)|mint:P9WJB9|refseq:NP_218397.1|refseq:WP_003399988.1|interpro:IPR036894|interpro:IPR004401(Conserved hypothetical protein CHP00103)	refseq:NP_035762.2|ensembl:ENSMUSG00000021277(gene)|ensembl:ENSMUST00000021706(transcript)|go:"GO:0001817"(regulation of cytokine production)|go:"GO:0002224"(toll-like receptor signaling pathway)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005164"(tumor necrosis factor receptor binding)|go:"GO:0005768"(endosome)|go:"GO:0006915"(apoptotic process)|go:"GO:0008063"(Toll signaling pathway)|go:"GO:0008270"(zinc ion binding)|go:"GO:0009898"(cytoplasmic side of plasma membrane)|go:"GO:0019901"(protein kinase binding)|go:"GO:0019903"(protein phosphatase binding)|go:"GO:0030162"(regulation of proteolysis)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0031996"(thioesterase binding)|go:"GO:0032088"(negative regulation of NF-kappaB transcription factor activity)|go:"GO:0032648"(regulation of interferon-beta production)|go:"GO:0033209"(tumor necrosis factor-mediated signaling pathway)|go:"GO:0035631"(CD40 receptor complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0043122"(regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0045087"(innate immune response)|go:"GO:0046330"(positive regulation of JNK cascade)|go:"GO:0050688"(regulation of defense response to virus)|go:"GO:0070534"(protein K63-linked ubiquitination)|interpro:IPR001293(Zinc finger, TRAF-type)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR002083(MATH)|interpro:IPR008974(TRAF-like)|interpro:IPR012227(TNF receptor-associated factor TRAF)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017907|interpro:IPR027128|interpro:IPR037304|interpro:IPR043211|mint:Q60803|rcsb pdb:4GHU|reactome:R-MMU-5668541|reactome:R-MMU-5676594|reactome:R-MMU-5689896|reactome:R-MMU-936964|refseq:XP_006515861.1|refseq:XP_006515862.1|refseq:XP_006515863.1|refseq:XP_006515864.1|dip:DIP-34050N	-	-	-	figure legend:ST5|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2020/07/08	2020/08/14	rogid:BspTx2RZuhJaQ319NBDIyOreqfE83332	rogid:2MrUSSGdyGB3zrZ39xovGDK6ysE10090	rigid:iOAYGa9Xcmc2fUoxKZLvuSQRtWY	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q60803	uniprotkb:P9WNI7	intact:EBI-520135|uniprotkb:B2RPW3|uniprotkb:Q62380|ensembl:ENSMUSP00000021706	intact:EBI-9027314|uniprotkb:P95242|uniprotkb:L0T9C9	psi-mi:traf3_mouse(display_long)|uniprotkb:CD40 receptor-associated factor 1(gene name synonym)|uniprotkb:TRAFAMN(gene name synonym)|uniprotkb:Traf3(gene name)|psi-mi:Traf3(display_short)|uniprotkb:Craf1(gene name synonym)|uniprotkb:Trafamn(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase TRAF3(gene name synonym)	psi-mi:esxo_myctu(display_long)|uniprotkb:esxO(gene name)|psi-mi:esxO(display_short)|uniprotkb:MTCY98.15c(orf name)|uniprotkb:Rv2346c(locus name)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2018)	doi:10.1093/nar/gkx1173|imex:IM-28235|pubmed:29165646	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:83332(myctu)|taxid:83332("Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)")	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0471"(MINT)	intact:EBI-25768550|imex:IM-28235-165	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_035762.2|ensembl:ENSMUSG00000021277(gene)|ensembl:ENSMUST00000021706(transcript)|go:"GO:0001817"(regulation of cytokine production)|go:"GO:0002224"(toll-like receptor signaling pathway)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005164"(tumor necrosis factor receptor binding)|go:"GO:0005768"(endosome)|go:"GO:0006915"(apoptotic process)|go:"GO:0008063"(Toll signaling pathway)|go:"GO:0008270"(zinc ion binding)|go:"GO:0009898"(cytoplasmic side of plasma membrane)|go:"GO:0019901"(protein kinase binding)|go:"GO:0019903"(protein phosphatase binding)|go:"GO:0030162"(regulation of proteolysis)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0031996"(thioesterase binding)|go:"GO:0032088"(negative regulation of NF-kappaB transcription factor activity)|go:"GO:0032648"(regulation of interferon-beta production)|go:"GO:0033209"(tumor necrosis factor-mediated signaling pathway)|go:"GO:0035631"(CD40 receptor complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0043122"(regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0045087"(innate immune response)|go:"GO:0046330"(positive regulation of JNK cascade)|go:"GO:0050688"(regulation of defense response to virus)|go:"GO:0070534"(protein K63-linked ubiquitination)|interpro:IPR001293(Zinc finger, TRAF-type)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR002083(MATH)|interpro:IPR008974(TRAF-like)|interpro:IPR012227(TNF receptor-associated factor TRAF)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017907|interpro:IPR027128|interpro:IPR037304|interpro:IPR043211|mint:Q60803|rcsb pdb:4GHU|reactome:R-MMU-5668541|reactome:R-MMU-5676594|reactome:R-MMU-5689896|reactome:R-MMU-936964|refseq:XP_006515861.1|refseq:XP_006515862.1|refseq:XP_006515863.1|refseq:XP_006515864.1|dip:DIP-34050N	mint:P9WNI7|interpro:IPR036689|interpro:IPR009416(Protein of unknown function DUF1066)|interpro:IPR010310(Protein of unknown function DUF909)|refseq:NP_216862.1|refseq:WP_003899283.1|go:"GO:0005576"(extracellular region)|go:"GO:0005618"(cell wall)|go:"GO:0005886"(plasma membrane)|rcsb pdb:3OGI|rcsb pdb:4GZR	-	-	-	figure legend:ST5|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2020/07/08	2020/08/14	rogid:2MrUSSGdyGB3zrZ39xovGDK6ysE10090	rogid:jYoNmHY+G6+S39CX1qRFCxjy0xw83332	rigid:OlZradVV3yXjgaoLN+BWgpp/lOU	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P9WIT1	uniprotkb:Q60803	intact:EBI-25767539|uniprotkb:L0TBU2|uniprotkb:Q50685|uniprotkb:Q7D7C5	intact:EBI-520135|uniprotkb:B2RPW3|uniprotkb:Q62380|ensembl:ENSMUSP00000021706	psi-mi:y2280_myctu(display_long)|uniprotkb:Rv2280(locus name)	psi-mi:traf3_mouse(display_long)|uniprotkb:CD40 receptor-associated factor 1(gene name synonym)|uniprotkb:TRAFAMN(gene name synonym)|uniprotkb:Traf3(gene name)|psi-mi:Traf3(display_short)|uniprotkb:Craf1(gene name synonym)|uniprotkb:Trafamn(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase TRAF3(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2018)	doi:10.1093/nar/gkx1173|imex:IM-28235|pubmed:29165646	taxid:83332(myctu)|taxid:83332("Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)")	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0471"(MINT)	intact:EBI-25768544|imex:IM-28235-95	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	go:"GO:0005618"(cell wall)|go:"GO:0005886"(plasma membrane)|go:"GO:0016491"(oxidoreductase activity)|go:"GO:0071949"(FAD binding)|interpro:IPR016169(CO dehydrogenase flavoprotein-like, FAD-binding, subdomain 2)|mint:P9WIT1|refseq:WP_003411690.1|interpro:IPR016166(FAD-binding, type 2)|interpro:IPR036318|interpro:IPR016164(FAD-linked oxidase-like, C-terminal)|interpro:IPR004113(FAD-linked oxidase, C-terminal)|interpro:IPR006094(FAD linked oxidase, N-terminal)|interpro:IPR016171(Vanillyl-alcohol oxidase, C-terminal subdomain 2)	refseq:NP_035762.2|ensembl:ENSMUSG00000021277(gene)|ensembl:ENSMUST00000021706(transcript)|go:"GO:0001817"(regulation of cytokine production)|go:"GO:0002224"(toll-like receptor signaling pathway)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005164"(tumor necrosis factor receptor binding)|go:"GO:0005768"(endosome)|go:"GO:0006915"(apoptotic process)|go:"GO:0008063"(Toll signaling pathway)|go:"GO:0008270"(zinc ion binding)|go:"GO:0009898"(cytoplasmic side of plasma membrane)|go:"GO:0019901"(protein kinase binding)|go:"GO:0019903"(protein phosphatase binding)|go:"GO:0030162"(regulation of proteolysis)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0031996"(thioesterase binding)|go:"GO:0032088"(negative regulation of NF-kappaB transcription factor activity)|go:"GO:0032648"(regulation of interferon-beta production)|go:"GO:0033209"(tumor necrosis factor-mediated signaling pathway)|go:"GO:0035631"(CD40 receptor complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0043122"(regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0045087"(innate immune response)|go:"GO:0046330"(positive regulation of JNK cascade)|go:"GO:0050688"(regulation of defense response to virus)|go:"GO:0070534"(protein K63-linked ubiquitination)|interpro:IPR001293(Zinc finger, TRAF-type)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR002083(MATH)|interpro:IPR008974(TRAF-like)|interpro:IPR012227(TNF receptor-associated factor TRAF)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017907|interpro:IPR027128|interpro:IPR037304|interpro:IPR043211|mint:Q60803|rcsb pdb:4GHU|reactome:R-MMU-5668541|reactome:R-MMU-5676594|reactome:R-MMU-5689896|reactome:R-MMU-936964|refseq:XP_006515861.1|refseq:XP_006515862.1|refseq:XP_006515863.1|refseq:XP_006515864.1|dip:DIP-34050N	-	-	-	figure legend:ST5|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2020/07/08	2020/08/14	rogid:TvFI3uuw9zREl1q0DeWIsHmCSEk83332	rogid:2MrUSSGdyGB3zrZ39xovGDK6ysE10090	rigid:AdxecmFLO7KZmA0lmYDICo7x3jw	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:O07177	uniprotkb:Q60803	intact:EBI-25767633|uniprotkb:L0T5L4	intact:EBI-520135|uniprotkb:B2RPW3|uniprotkb:Q62380|ensembl:ENSMUSP00000021706	psi-mi:mak1_myctu(display_long)|uniprotkb:mak(gene name)|psi-mi:mak(display_short)|uniprotkb:Maltose-1-phosphate synthase(gene name synonym)|uniprotkb:Rv0127(locus name)	psi-mi:traf3_mouse(display_long)|uniprotkb:CD40 receptor-associated factor 1(gene name synonym)|uniprotkb:TRAFAMN(gene name synonym)|uniprotkb:Traf3(gene name)|psi-mi:Traf3(display_short)|uniprotkb:Craf1(gene name synonym)|uniprotkb:Trafamn(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase TRAF3(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2018)	doi:10.1093/nar/gkx1173|imex:IM-28235|pubmed:29165646	taxid:83332(myctu)|taxid:83332("Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)")	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0471"(MINT)	intact:EBI-25768538|imex:IM-28235-77	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	go:"GO:0005978"(glycogen biosynthetic process)|go:"GO:0005992"(trehalose biosynthetic process)|go:"GO:0016301"(kinase activity)|go:"GO:0046835"(carbohydrate phosphorylation)|rcsb pdb:4O7O|rcsb pdb:4O7P|go:"GO:0005524"(ATP binding)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|mint:O07177|refseq:NP_214641.1|refseq:WP_003916610.1|interpro:IPR011009(Protein kinase-like)|interpro:IPR040999	refseq:NP_035762.2|ensembl:ENSMUSG00000021277(gene)|ensembl:ENSMUST00000021706(transcript)|go:"GO:0001817"(regulation of cytokine production)|go:"GO:0002224"(toll-like receptor signaling pathway)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005164"(tumor necrosis factor receptor binding)|go:"GO:0005768"(endosome)|go:"GO:0006915"(apoptotic process)|go:"GO:0008063"(Toll signaling pathway)|go:"GO:0008270"(zinc ion binding)|go:"GO:0009898"(cytoplasmic side of plasma membrane)|go:"GO:0019901"(protein kinase binding)|go:"GO:0019903"(protein phosphatase binding)|go:"GO:0030162"(regulation of proteolysis)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0031996"(thioesterase binding)|go:"GO:0032088"(negative regulation of NF-kappaB transcription factor activity)|go:"GO:0032648"(regulation of interferon-beta production)|go:"GO:0033209"(tumor necrosis factor-mediated signaling pathway)|go:"GO:0035631"(CD40 receptor complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0043122"(regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0045087"(innate immune response)|go:"GO:0046330"(positive regulation of JNK cascade)|go:"GO:0050688"(regulation of defense response to virus)|go:"GO:0070534"(protein K63-linked ubiquitination)|interpro:IPR001293(Zinc finger, TRAF-type)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR002083(MATH)|interpro:IPR008974(TRAF-like)|interpro:IPR012227(TNF receptor-associated factor TRAF)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017907|interpro:IPR027128|interpro:IPR037304|interpro:IPR043211|mint:Q60803|rcsb pdb:4GHU|reactome:R-MMU-5668541|reactome:R-MMU-5676594|reactome:R-MMU-5689896|reactome:R-MMU-936964|refseq:XP_006515861.1|refseq:XP_006515862.1|refseq:XP_006515863.1|refseq:XP_006515864.1|dip:DIP-34050N	-	-	-	figure legend:ST5|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2020/07/08	2020/08/14	rogid:kpl6jZ4UbJUq/kfAlHBYpJAJV4E83332	rogid:2MrUSSGdyGB3zrZ39xovGDK6ysE10090	rigid:DFLcQ5/YK6/crU/Ev8C+P/84ipI	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P9WN37	uniprotkb:Q60803	intact:EBI-25767601|uniprotkb:L0T968|uniprotkb:P64245|uniprotkb:Q10378	intact:EBI-520135|uniprotkb:B2RPW3|uniprotkb:Q62380|ensembl:ENSMUSP00000021706	psi-mi:gln1a_myctu(display_long)|uniprotkb:glnA2(gene name)|psi-mi:glnA2(display_short)|uniprotkb:Glutamate--ammonia ligase(gene name synonym)|uniprotkb:Glutamine synthetase I alpha(gene name synonym)|uniprotkb:MTCY190.33c(orf name)|uniprotkb:MTCY427.03c(orf name)|uniprotkb:Rv2222c(locus name)	psi-mi:traf3_mouse(display_long)|uniprotkb:CD40 receptor-associated factor 1(gene name synonym)|uniprotkb:TRAFAMN(gene name synonym)|uniprotkb:Traf3(gene name)|psi-mi:Traf3(display_short)|uniprotkb:Craf1(gene name synonym)|uniprotkb:Trafamn(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase TRAF3(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2018)	doi:10.1093/nar/gkx1173|imex:IM-28235|pubmed:29165646	taxid:83332(myctu)|taxid:83332("Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)")	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0471"(MINT)	intact:EBI-25768532|imex:IM-28235-23	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	go:"GO:0004356"(glutamate-ammonia ligase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0006542"(glutamine biosynthetic process)|go:"GO:0046872"(metal ion binding)|go:"GO:0050001"(D-glutaminase activity)|mint:P9WN37|refseq:NP_216738.1|refseq:WP_003411482.1|interpro:IPR008147(Glutamine synthetase, beta-Grasp)|interpro:IPR036651|interpro:IPR014746(Glutamine synthetase/guanido kinase, catalytic region)|interpro:IPR008146(Glutamine synthetase, catalytic region)|interpro:IPR027303	refseq:NP_035762.2|ensembl:ENSMUSG00000021277(gene)|ensembl:ENSMUST00000021706(transcript)|go:"GO:0001817"(regulation of cytokine production)|go:"GO:0002224"(toll-like receptor signaling pathway)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005164"(tumor necrosis factor receptor binding)|go:"GO:0005768"(endosome)|go:"GO:0006915"(apoptotic process)|go:"GO:0008063"(Toll signaling pathway)|go:"GO:0008270"(zinc ion binding)|go:"GO:0009898"(cytoplasmic side of plasma membrane)|go:"GO:0019901"(protein kinase binding)|go:"GO:0019903"(protein phosphatase binding)|go:"GO:0030162"(regulation of proteolysis)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0031996"(thioesterase binding)|go:"GO:0032088"(negative regulation of NF-kappaB transcription factor activity)|go:"GO:0032648"(regulation of interferon-beta production)|go:"GO:0033209"(tumor necrosis factor-mediated signaling pathway)|go:"GO:0035631"(CD40 receptor complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0043122"(regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0045087"(innate immune response)|go:"GO:0046330"(positive regulation of JNK cascade)|go:"GO:0050688"(regulation of defense response to virus)|go:"GO:0070534"(protein K63-linked ubiquitination)|interpro:IPR001293(Zinc finger, TRAF-type)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR002083(MATH)|interpro:IPR008974(TRAF-like)|interpro:IPR012227(TNF receptor-associated factor TRAF)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017907|interpro:IPR027128|interpro:IPR037304|interpro:IPR043211|mint:Q60803|rcsb pdb:4GHU|reactome:R-MMU-5668541|reactome:R-MMU-5676594|reactome:R-MMU-5689896|reactome:R-MMU-936964|refseq:XP_006515861.1|refseq:XP_006515862.1|refseq:XP_006515863.1|refseq:XP_006515864.1|dip:DIP-34050N	-	-	-	figure legend:ST5|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2020/07/08	2020/08/14	rogid:LDIpolmw5yhv2iG5+8HKbWlwT8883332	rogid:2MrUSSGdyGB3zrZ39xovGDK6ysE10090	rigid:o8ugLO+hCTeif+VhGDZBmyG4QmY	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:O69689	uniprotkb:Q60803	intact:EBI-25767781|uniprotkb:F2GFU4|uniprotkb:I6Y4D4|uniprotkb:Q7D501	intact:EBI-520135|uniprotkb:B2RPW3|uniprotkb:Q62380|ensembl:ENSMUSP00000021706	psi-mi:aspat_myctu(display_long)|uniprotkb:Rv3722c(locus name)	psi-mi:traf3_mouse(display_long)|uniprotkb:CD40 receptor-associated factor 1(gene name synonym)|uniprotkb:TRAFAMN(gene name synonym)|uniprotkb:Traf3(gene name)|psi-mi:Traf3(display_short)|uniprotkb:Craf1(gene name synonym)|uniprotkb:Trafamn(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase TRAF3(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2018)	doi:10.1093/nar/gkx1173|imex:IM-28235|pubmed:29165646	taxid:83332(myctu)|taxid:83332("Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)")	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0471"(MINT)	intact:EBI-25768526|imex:IM-28235-163	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	go:"GO:0004069"("L-aspartate:2-oxoglutarate aminotransferase activity")|go:"GO:0005576"(extracellular region)|rcsb pdb:5C6U|rcsb pdb:6U78|rcsb pdb:6U7A|mint:O69689|refseq:NP_218239.2|refseq:WP_003899653.1|interpro:IPR024551|interpro:IPR015424(Pyridoxal phosphate-dependent transferase, major region)|interpro:IPR015422(Pyridoxal phosphate-dependent transferase, major region, subdomain 2)|interpro:IPR015421(Pyridoxal phosphate-dependent transferase, major region, subdomain 1)	refseq:NP_035762.2|ensembl:ENSMUSG00000021277(gene)|ensembl:ENSMUST00000021706(transcript)|go:"GO:0001817"(regulation of cytokine production)|go:"GO:0002224"(toll-like receptor signaling pathway)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005164"(tumor necrosis factor receptor binding)|go:"GO:0005768"(endosome)|go:"GO:0006915"(apoptotic process)|go:"GO:0008063"(Toll signaling pathway)|go:"GO:0008270"(zinc ion binding)|go:"GO:0009898"(cytoplasmic side of plasma membrane)|go:"GO:0019901"(protein kinase binding)|go:"GO:0019903"(protein phosphatase binding)|go:"GO:0030162"(regulation of proteolysis)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0031996"(thioesterase binding)|go:"GO:0032088"(negative regulation of NF-kappaB transcription factor activity)|go:"GO:0032648"(regulation of interferon-beta production)|go:"GO:0033209"(tumor necrosis factor-mediated signaling pathway)|go:"GO:0035631"(CD40 receptor complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0043122"(regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0045087"(innate immune response)|go:"GO:0046330"(positive regulation of JNK cascade)|go:"GO:0050688"(regulation of defense response to virus)|go:"GO:0070534"(protein K63-linked ubiquitination)|interpro:IPR001293(Zinc finger, TRAF-type)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR002083(MATH)|interpro:IPR008974(TRAF-like)|interpro:IPR012227(TNF receptor-associated factor TRAF)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017907|interpro:IPR027128|interpro:IPR037304|interpro:IPR043211|mint:Q60803|rcsb pdb:4GHU|reactome:R-MMU-5668541|reactome:R-MMU-5676594|reactome:R-MMU-5689896|reactome:R-MMU-936964|refseq:XP_006515861.1|refseq:XP_006515862.1|refseq:XP_006515863.1|refseq:XP_006515864.1|dip:DIP-34050N	-	-	-	figure legend:ST5|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2020/07/08	2020/08/14	rogid:TGWnUCrIwLrRrMnna5+/w33GpgA83332	rogid:2MrUSSGdyGB3zrZ39xovGDK6ysE10090	rigid:lUH5cEASKJzG1UHH7zTSaovQ7VE	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P35242	uniprotkb:O53319	intact:EBI-8394157|intact:MINT-4134384	intact:EBI-25767766|uniprotkb:I6X6K2|uniprotkb:L0TEH7	psi-mi:sftpa_mouse(display_long)|uniprotkb:Sftpa1(gene name)|psi-mi:Sftpa1(display_short)|uniprotkb:Sftp1(gene name synonym)|uniprotkb:Sftp-1(gene name synonym)|uniprotkb:Sftpa(gene name synonym)	psi-mi:o53319_myctu(display_long)|uniprotkb:Rv3169(locus name)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2018)	doi:10.1093/nar/gkx1173|imex:IM-28235|pubmed:29165646	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:83332(myctu)|taxid:83332("Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)")	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0471"(MINT)	intact:EBI-25768520|imex:IM-28235-205	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	interpro:IPR016187(C-type lectin fold)|interpro:IPR016186(C-type lectin-like)|interpro:IPR018378|interpro:IPR033990|mint:P35242|go:"GO:0005581"(collagen trimer)|go:"GO:0005615"(extracellular space)|go:"GO:0005771"(multivesicular body)|go:"GO:0005791"(rough endoplasmic reticulum)|go:"GO:0007585"(respiratory gaseous exchange by respiratory system)|go:"GO:0008228"(opsonization)|go:"GO:0030246"(carbohydrate binding)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0046872"(metal ion binding)|go:"GO:0050766"(positive regulation of phagocytosis)|go:"GO:0062023"(collagen-containing extracellular matrix)|reactome:R-MMU-166016|reactome:R-MMU-391160|reactome:R-MMU-5683826|reactome:R-MMU-5686938|interpro:IPR001304(C-type lectin)	go:"GO:0005886"(plasma membrane)|mint:O53319|refseq:NP_217685.1|refseq:WP_003416605.1	-	function:In presence of calcium ions, it binds to surfactant phospholipids and contributes to lower the surface tension at the air-liquid interface in the alveoli of the mammalian lung and is essential for normal respiration|comment:mint	-	figure legend:ST5|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2020/07/08	2020/08/14	rogid:Xm0KET9Tv37T4jZJm2WSiFBi2F810090	rogid:Gd1O5B5qTAQflXzn9MR+6fgqvDs83332	rigid:oLRJcNjVsOygWRL9GgYOGoU3QNI	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P35242	uniprotkb:O50440	intact:EBI-8394157|intact:MINT-4134384	intact:EBI-25767742|uniprotkb:I6XXB2|uniprotkb:L0T7J5	psi-mi:sftpa_mouse(display_long)|uniprotkb:Sftpa1(gene name)|psi-mi:Sftpa1(display_short)|uniprotkb:Sftp1(gene name synonym)|uniprotkb:Sftp-1(gene name synonym)|uniprotkb:Sftpa(gene name synonym)	psi-mi:chp2_myctu(display_long)|uniprotkb:chp2(gene name)|psi-mi:chp2(display_short)|uniprotkb:LH57_06500(orf name)|uniprotkb:P425_01234(orf name)|uniprotkb:Rv1184c(locus name)|uniprotkb:RVBD_1184c(locus name)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2018)	doi:10.1093/nar/gkx1173|imex:IM-28235|pubmed:29165646	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:83332(myctu)|taxid:83332("Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)")	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0471"(MINT)	intact:EBI-25768514|imex:IM-28235-327	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	interpro:IPR016187(C-type lectin fold)|interpro:IPR016186(C-type lectin-like)|interpro:IPR018378|interpro:IPR033990|mint:P35242|go:"GO:0005581"(collagen trimer)|go:"GO:0005615"(extracellular space)|go:"GO:0005771"(multivesicular body)|go:"GO:0005791"(rough endoplasmic reticulum)|go:"GO:0007585"(respiratory gaseous exchange by respiratory system)|go:"GO:0008228"(opsonization)|go:"GO:0030246"(carbohydrate binding)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0046872"(metal ion binding)|go:"GO:0050766"(positive regulation of phagocytosis)|go:"GO:0062023"(collagen-containing extracellular matrix)|reactome:R-MMU-166016|reactome:R-MMU-391160|reactome:R-MMU-5683826|reactome:R-MMU-5686938|interpro:IPR001304(C-type lectin)	go:"GO:0005886"(plasma membrane)|go:"GO:0006629"(lipid metabolic process)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016746"(acyltransferase activity)|go:"GO:0005618"(cell wall)|mint:O50440|refseq:NP_215700.1|refseq:WP_003406195.1|interpro:IPR013228(PE-PPE, C-terminal)	-	function:In presence of calcium ions, it binds to surfactant phospholipids and contributes to lower the surface tension at the air-liquid interface in the alveoli of the mammalian lung and is essential for normal respiration|comment:mint	-	figure legend:ST5|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2020/07/08	2020/08/14	rogid:Xm0KET9Tv37T4jZJm2WSiFBi2F810090	rogid:IXzYfb7UxFgqBXPZ6NZHLy3hdTc83332	rigid:NAjfEYy3g9uZDcIK2dvdN+hTChQ	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P35242	uniprotkb:P9WJB9	intact:EBI-8394157|intact:MINT-4134384	intact:EBI-25767670|uniprotkb:L0TE21|uniprotkb:O69744|uniprotkb:Q7D4P0	psi-mi:sftpa_mouse(display_long)|uniprotkb:Sftpa1(gene name)|psi-mi:Sftpa1(display_short)|uniprotkb:Sftp1(gene name synonym)|uniprotkb:Sftp-1(gene name synonym)|uniprotkb:Sftpa(gene name synonym)	psi-mi:espl_myctu(display_long)|uniprotkb:espL(gene name)|psi-mi:espL(display_short)|uniprotkb:Rv3880c(locus name)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2018)	doi:10.1093/nar/gkx1173|imex:IM-28235|pubmed:29165646	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:83332(myctu)|taxid:83332("Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)")	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0471"(MINT)	intact:EBI-25768508|imex:IM-28235-161	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	interpro:IPR016187(C-type lectin fold)|interpro:IPR016186(C-type lectin-like)|interpro:IPR018378|interpro:IPR033990|mint:P35242|go:"GO:0005581"(collagen trimer)|go:"GO:0005615"(extracellular space)|go:"GO:0005771"(multivesicular body)|go:"GO:0005791"(rough endoplasmic reticulum)|go:"GO:0007585"(respiratory gaseous exchange by respiratory system)|go:"GO:0008228"(opsonization)|go:"GO:0030246"(carbohydrate binding)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0046872"(metal ion binding)|go:"GO:0050766"(positive regulation of phagocytosis)|go:"GO:0062023"(collagen-containing extracellular matrix)|reactome:R-MMU-166016|reactome:R-MMU-391160|reactome:R-MMU-5683826|reactome:R-MMU-5686938|interpro:IPR001304(C-type lectin)	go:"GO:0003677"(DNA binding)|go:"GO:0005618"(cell wall)|go:"GO:0005886"(plasma membrane)|go:"GO:0052170"(suppression by symbiont of host innate immune response)|mint:P9WJB9|refseq:NP_218397.1|refseq:WP_003399988.1|interpro:IPR036894|interpro:IPR004401(Conserved hypothetical protein CHP00103)	-	function:In presence of calcium ions, it binds to surfactant phospholipids and contributes to lower the surface tension at the air-liquid interface in the alveoli of the mammalian lung and is essential for normal respiration|comment:mint	-	figure legend:ST5|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2020/07/08	2020/08/14	rogid:Xm0KET9Tv37T4jZJm2WSiFBi2F810090	rogid:BspTx2RZuhJaQ319NBDIyOreqfE83332	rigid:soRnFQOenojF2CUMfff9E6GUQms	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P35242	uniprotkb:P9WIT1	intact:EBI-8394157|intact:MINT-4134384	intact:EBI-25767539|uniprotkb:L0TBU2|uniprotkb:Q50685|uniprotkb:Q7D7C5	psi-mi:sftpa_mouse(display_long)|uniprotkb:Sftpa1(gene name)|psi-mi:Sftpa1(display_short)|uniprotkb:Sftp1(gene name synonym)|uniprotkb:Sftp-1(gene name synonym)|uniprotkb:Sftpa(gene name synonym)	psi-mi:y2280_myctu(display_long)|uniprotkb:Rv2280(locus name)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2018)	doi:10.1093/nar/gkx1173|imex:IM-28235|pubmed:29165646	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:83332(myctu)|taxid:83332("Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)")	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0471"(MINT)	intact:EBI-25768502|imex:IM-28235-93	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	interpro:IPR016187(C-type lectin fold)|interpro:IPR016186(C-type lectin-like)|interpro:IPR018378|interpro:IPR033990|mint:P35242|go:"GO:0005581"(collagen trimer)|go:"GO:0005615"(extracellular space)|go:"GO:0005771"(multivesicular body)|go:"GO:0005791"(rough endoplasmic reticulum)|go:"GO:0007585"(respiratory gaseous exchange by respiratory system)|go:"GO:0008228"(opsonization)|go:"GO:0030246"(carbohydrate binding)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0046872"(metal ion binding)|go:"GO:0050766"(positive regulation of phagocytosis)|go:"GO:0062023"(collagen-containing extracellular matrix)|reactome:R-MMU-166016|reactome:R-MMU-391160|reactome:R-MMU-5683826|reactome:R-MMU-5686938|interpro:IPR001304(C-type lectin)	go:"GO:0005618"(cell wall)|go:"GO:0005886"(plasma membrane)|go:"GO:0016491"(oxidoreductase activity)|go:"GO:0071949"(FAD binding)|interpro:IPR016169(CO dehydrogenase flavoprotein-like, FAD-binding, subdomain 2)|mint:P9WIT1|refseq:WP_003411690.1|interpro:IPR016166(FAD-binding, type 2)|interpro:IPR036318|interpro:IPR016164(FAD-linked oxidase-like, C-terminal)|interpro:IPR004113(FAD-linked oxidase, C-terminal)|interpro:IPR006094(FAD linked oxidase, N-terminal)|interpro:IPR016171(Vanillyl-alcohol oxidase, C-terminal subdomain 2)	-	function:In presence of calcium ions, it binds to surfactant phospholipids and contributes to lower the surface tension at the air-liquid interface in the alveoli of the mammalian lung and is essential for normal respiration|comment:mint	-	figure legend:ST5|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2020/07/08	2020/08/14	rogid:Xm0KET9Tv37T4jZJm2WSiFBi2F810090	rogid:TvFI3uuw9zREl1q0DeWIsHmCSEk83332	rigid:c5xNHHXt+4/++d0EQrIcdT81BJw	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P35242	uniprotkb:O07177	intact:EBI-8394157|intact:MINT-4134384	intact:EBI-25767633|uniprotkb:L0T5L4	psi-mi:sftpa_mouse(display_long)|uniprotkb:Sftpa1(gene name)|psi-mi:Sftpa1(display_short)|uniprotkb:Sftp1(gene name synonym)|uniprotkb:Sftp-1(gene name synonym)|uniprotkb:Sftpa(gene name synonym)	psi-mi:mak1_myctu(display_long)|uniprotkb:mak(gene name)|psi-mi:mak(display_short)|uniprotkb:Maltose-1-phosphate synthase(gene name synonym)|uniprotkb:Rv0127(locus name)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2018)	doi:10.1093/nar/gkx1173|imex:IM-28235|pubmed:29165646	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:83332(myctu)|taxid:83332("Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)")	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0471"(MINT)	intact:EBI-25768496|imex:IM-28235-287	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	interpro:IPR016187(C-type lectin fold)|interpro:IPR016186(C-type lectin-like)|interpro:IPR018378|interpro:IPR033990|mint:P35242|go:"GO:0005581"(collagen trimer)|go:"GO:0005615"(extracellular space)|go:"GO:0005771"(multivesicular body)|go:"GO:0005791"(rough endoplasmic reticulum)|go:"GO:0007585"(respiratory gaseous exchange by respiratory system)|go:"GO:0008228"(opsonization)|go:"GO:0030246"(carbohydrate binding)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0046872"(metal ion binding)|go:"GO:0050766"(positive regulation of phagocytosis)|go:"GO:0062023"(collagen-containing extracellular matrix)|reactome:R-MMU-166016|reactome:R-MMU-391160|reactome:R-MMU-5683826|reactome:R-MMU-5686938|interpro:IPR001304(C-type lectin)	go:"GO:0005978"(glycogen biosynthetic process)|go:"GO:0005992"(trehalose biosynthetic process)|go:"GO:0016301"(kinase activity)|go:"GO:0046835"(carbohydrate phosphorylation)|rcsb pdb:4O7O|rcsb pdb:4O7P|go:"GO:0005524"(ATP binding)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|mint:O07177|refseq:NP_214641.1|refseq:WP_003916610.1|interpro:IPR011009(Protein kinase-like)|interpro:IPR040999	-	function:In presence of calcium ions, it binds to surfactant phospholipids and contributes to lower the surface tension at the air-liquid interface in the alveoli of the mammalian lung and is essential for normal respiration|comment:mint	-	figure legend:ST5|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2020/07/08	2020/08/14	rogid:Xm0KET9Tv37T4jZJm2WSiFBi2F810090	rogid:kpl6jZ4UbJUq/kfAlHBYpJAJV4E83332	rigid:etYJx6iiFTqAitYmJN8MYHO9II4	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P35242	uniprotkb:P71619	intact:EBI-8394157|intact:MINT-4134384	intact:EBI-25767582|uniprotkb:F2GLA0|uniprotkb:I6YAD4	psi-mi:sftpa_mouse(display_long)|uniprotkb:Sftpa1(gene name)|psi-mi:Sftpa1(display_short)|uniprotkb:Sftp1(gene name synonym)|uniprotkb:Sftp-1(gene name synonym)|uniprotkb:Sftpa(gene name synonym)	psi-mi:p71619_myctu(display_long)|uniprotkb:ugpB(gene name)|psi-mi:ugpB(display_short)|uniprotkb:Rv2833c(locus name)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2018)	doi:10.1093/nar/gkx1173|imex:IM-28235|pubmed:29165646	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:83332(myctu)|taxid:83332("Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)")	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0471"(MINT)	intact:EBI-25768490|imex:IM-28235-285	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	interpro:IPR016187(C-type lectin fold)|interpro:IPR016186(C-type lectin-like)|interpro:IPR018378|interpro:IPR033990|mint:P35242|go:"GO:0005581"(collagen trimer)|go:"GO:0005615"(extracellular space)|go:"GO:0005771"(multivesicular body)|go:"GO:0005791"(rough endoplasmic reticulum)|go:"GO:0007585"(respiratory gaseous exchange by respiratory system)|go:"GO:0008228"(opsonization)|go:"GO:0030246"(carbohydrate binding)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0046872"(metal ion binding)|go:"GO:0050766"(positive regulation of phagocytosis)|go:"GO:0062023"(collagen-containing extracellular matrix)|reactome:R-MMU-166016|reactome:R-MMU-391160|reactome:R-MMU-5683826|reactome:R-MMU-5686938|interpro:IPR001304(C-type lectin)	go:"GO:0005886"(plasma membrane)|rcsb pdb:6R1B|mint:P71619|refseq:NP_217349.1|refseq:WP_003414501.1|interpro:IPR006059(Bacterial extracellular solute-binding, family 1)|interpro:IPR006311(Twin-arginine translocation pathway signal)	-	function:In presence of calcium ions, it binds to surfactant phospholipids and contributes to lower the surface tension at the air-liquid interface in the alveoli of the mammalian lung and is essential for normal respiration|comment:mint	-	figure legend:ST5|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2020/07/08	2020/08/14	rogid:Xm0KET9Tv37T4jZJm2WSiFBi2F810090	rogid:ldo4FA/3ddzSo1mfnNEPte27F1083332	rigid:peqnizwA/mBW6YzpBZVFTD7Bycw	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P35242	uniprotkb:O69689	intact:EBI-8394157|intact:MINT-4134384	intact:EBI-25767781|uniprotkb:F2GFU4|uniprotkb:I6Y4D4|uniprotkb:Q7D501	psi-mi:sftpa_mouse(display_long)|uniprotkb:Sftpa1(gene name)|psi-mi:Sftpa1(display_short)|uniprotkb:Sftp1(gene name synonym)|uniprotkb:Sftp-1(gene name synonym)|uniprotkb:Sftpa(gene name synonym)	psi-mi:aspat_myctu(display_long)|uniprotkb:Rv3722c(locus name)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2018)	doi:10.1093/nar/gkx1173|imex:IM-28235|pubmed:29165646	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:83332(myctu)|taxid:83332("Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)")	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0471"(MINT)	intact:EBI-25768484|imex:IM-28235-159	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	interpro:IPR016187(C-type lectin fold)|interpro:IPR016186(C-type lectin-like)|interpro:IPR018378|interpro:IPR033990|mint:P35242|go:"GO:0005581"(collagen trimer)|go:"GO:0005615"(extracellular space)|go:"GO:0005771"(multivesicular body)|go:"GO:0005791"(rough endoplasmic reticulum)|go:"GO:0007585"(respiratory gaseous exchange by respiratory system)|go:"GO:0008228"(opsonization)|go:"GO:0030246"(carbohydrate binding)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0046872"(metal ion binding)|go:"GO:0050766"(positive regulation of phagocytosis)|go:"GO:0062023"(collagen-containing extracellular matrix)|reactome:R-MMU-166016|reactome:R-MMU-391160|reactome:R-MMU-5683826|reactome:R-MMU-5686938|interpro:IPR001304(C-type lectin)	go:"GO:0004069"("L-aspartate:2-oxoglutarate aminotransferase activity")|go:"GO:0005576"(extracellular region)|rcsb pdb:5C6U|rcsb pdb:6U78|rcsb pdb:6U7A|mint:O69689|refseq:NP_218239.2|refseq:WP_003899653.1|interpro:IPR024551|interpro:IPR015424(Pyridoxal phosphate-dependent transferase, major region)|interpro:IPR015422(Pyridoxal phosphate-dependent transferase, major region, subdomain 2)|interpro:IPR015421(Pyridoxal phosphate-dependent transferase, major region, subdomain 1)	-	function:In presence of calcium ions, it binds to surfactant phospholipids and contributes to lower the surface tension at the air-liquid interface in the alveoli of the mammalian lung and is essential for normal respiration|comment:mint	-	figure legend:ST5|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2020/07/08	2020/08/14	rogid:Xm0KET9Tv37T4jZJm2WSiFBi2F810090	rogid:TGWnUCrIwLrRrMnna5+/w33GpgA83332	rigid:e0pWovkPUbxgVkWpIa0/KzWpyj4	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:O50440	uniprotkb:O35718	intact:EBI-25767742|uniprotkb:I6XXB2|uniprotkb:L0T7J5	intact:EBI-2659360|uniprotkb:Q3U7X5|uniprotkb:P97803|ensembl:ENSMUSP00000059129	psi-mi:chp2_myctu(display_long)|uniprotkb:chp2(gene name)|psi-mi:chp2(display_short)|uniprotkb:LH57_06500(orf name)|uniprotkb:P425_01234(orf name)|uniprotkb:Rv1184c(locus name)|uniprotkb:RVBD_1184c(locus name)	psi-mi:socs3_mouse(display_long)|uniprotkb:Cytokine-inducible SH2 protein 3(gene name synonym)|uniprotkb:Protein EF-10(gene name synonym)|uniprotkb:Cis3(gene name synonym)|uniprotkb:Cish3(gene name synonym)|uniprotkb:Socs3(gene name)|psi-mi:Socs3(display_short)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2018)	doi:10.1093/nar/gkx1173|imex:IM-28235|pubmed:29165646	taxid:83332(myctu)|taxid:83332("Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)")	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0471"(MINT)	intact:EBI-25768478|imex:IM-28235-203	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	go:"GO:0005886"(plasma membrane)|go:"GO:0006629"(lipid metabolic process)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016746"(acyltransferase activity)|go:"GO:0005618"(cell wall)|mint:O50440|refseq:NP_215700.1|refseq:WP_003406195.1|interpro:IPR013228(PE-PPE, C-terminal)	refseq:XP_011247009.1|refseq:NP_031733.1|ensembl:ENSMUSG00000053113(gene)|ensembl:ENSMUST00000054002(transcript)|go:"GO:0001784"(phosphotyrosine residue binding)|go:"GO:0001932"(regulation of protein phosphorylation)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005942"(phosphatidylinositol 3-kinase complex)|go:"GO:0007165"(signal transduction)|go:"GO:0007259"(receptor signaling pathway via JAK-STAT)|go:"GO:0009968"(negative regulation of signal transduction)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0040008"(regulation of growth)|go:"GO:0042532"(negative regulation of tyrosine phosphorylation of STAT protein)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0045595"(regulation of cell differentiation)|go:"GO:0045597"(positive regulation of cell differentiation)|go:"GO:0046426"(negative regulation of receptor signaling pathway via JAK-STAT)|go:"GO:0046627"(negative regulation of insulin receptor signaling pathway)|go:"GO:0046854"(phosphatidylinositol phosphate biosynthetic process)|go:"GO:0046935"(1-phosphatidylinositol-3-kinase regulator activity)|go:"GO:0050728"(negative regulation of inflammatory response)|go:"GO:0060670"(branching involved in labyrinthine layer morphogenesis)|go:"GO:0060674"(placenta blood vessel development)|go:"GO:0060707"(trophoblast giant cell differentiation)|go:"GO:0060708"(spongiotrophoblast differentiation)|go:"GO:1990830"(cellular response to leukemia inhibitory factor)|interpro:IPR000980(SH2 motif)|interpro:IPR001496(SOCS protein, C-terminal)|interpro:IPR028414|interpro:IPR035863|interpro:IPR036036|interpro:IPR036860|mint:O35718|rcsb pdb:2BBU|rcsb pdb:2HMH|rcsb pdb:2JZ3|rcsb pdb:4GL9|reactome:R-MMU-1059683|reactome:R-MMU-877300|reactome:R-MMU-877312|reactome:R-MMU-8849474|reactome:R-MMU-8951664|reactome:R-MMU-909733|reactome:R-MMU-9705462|reactome:R-MMU-983168|dip:DIP-29137N	-	-	-	figure legend:ST5|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2020/07/08	2020/08/14	rogid:IXzYfb7UxFgqBXPZ6NZHLy3hdTc83332	rogid:SFk8FM1xo7SkodsiFXZYzTbLrYg10090	rigid:tn+5NX88wzS7FvMsXM/suS9+wso	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P9WJB9	uniprotkb:O35718	intact:EBI-25767670|uniprotkb:L0TE21|uniprotkb:O69744|uniprotkb:Q7D4P0	intact:EBI-2659360|uniprotkb:Q3U7X5|uniprotkb:P97803|ensembl:ENSMUSP00000059129	psi-mi:espl_myctu(display_long)|uniprotkb:espL(gene name)|psi-mi:espL(display_short)|uniprotkb:Rv3880c(locus name)	psi-mi:socs3_mouse(display_long)|uniprotkb:Cytokine-inducible SH2 protein 3(gene name synonym)|uniprotkb:Protein EF-10(gene name synonym)|uniprotkb:Cis3(gene name synonym)|uniprotkb:Cish3(gene name synonym)|uniprotkb:Socs3(gene name)|psi-mi:Socs3(display_short)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2018)	doi:10.1093/nar/gkx1173|imex:IM-28235|pubmed:29165646	taxid:83332(myctu)|taxid:83332("Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)")	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0471"(MINT)	intact:EBI-25768472|imex:IM-28235-201	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	go:"GO:0003677"(DNA binding)|go:"GO:0005618"(cell wall)|go:"GO:0005886"(plasma membrane)|go:"GO:0052170"(suppression by symbiont of host innate immune response)|mint:P9WJB9|refseq:NP_218397.1|refseq:WP_003399988.1|interpro:IPR036894|interpro:IPR004401(Conserved hypothetical protein CHP00103)	refseq:XP_011247009.1|refseq:NP_031733.1|ensembl:ENSMUSG00000053113(gene)|ensembl:ENSMUST00000054002(transcript)|go:"GO:0001784"(phosphotyrosine residue binding)|go:"GO:0001932"(regulation of protein phosphorylation)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005942"(phosphatidylinositol 3-kinase complex)|go:"GO:0007165"(signal transduction)|go:"GO:0007259"(receptor signaling pathway via JAK-STAT)|go:"GO:0009968"(negative regulation of signal transduction)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0040008"(regulation of growth)|go:"GO:0042532"(negative regulation of tyrosine phosphorylation of STAT protein)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0045595"(regulation of cell differentiation)|go:"GO:0045597"(positive regulation of cell differentiation)|go:"GO:0046426"(negative regulation of receptor signaling pathway via JAK-STAT)|go:"GO:0046627"(negative regulation of insulin receptor signaling pathway)|go:"GO:0046854"(phosphatidylinositol phosphate biosynthetic process)|go:"GO:0046935"(1-phosphatidylinositol-3-kinase regulator activity)|go:"GO:0050728"(negative regulation of inflammatory response)|go:"GO:0060670"(branching involved in labyrinthine layer morphogenesis)|go:"GO:0060674"(placenta blood vessel development)|go:"GO:0060707"(trophoblast giant cell differentiation)|go:"GO:0060708"(spongiotrophoblast differentiation)|go:"GO:1990830"(cellular response to leukemia inhibitory factor)|interpro:IPR000980(SH2 motif)|interpro:IPR001496(SOCS protein, C-terminal)|interpro:IPR028414|interpro:IPR035863|interpro:IPR036036|interpro:IPR036860|mint:O35718|rcsb pdb:2BBU|rcsb pdb:2HMH|rcsb pdb:2JZ3|rcsb pdb:4GL9|reactome:R-MMU-1059683|reactome:R-MMU-877300|reactome:R-MMU-877312|reactome:R-MMU-8849474|reactome:R-MMU-8951664|reactome:R-MMU-909733|reactome:R-MMU-9705462|reactome:R-MMU-983168|dip:DIP-29137N	-	-	-	figure legend:ST5|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2020/07/08	2020/08/14	rogid:BspTx2RZuhJaQ319NBDIyOreqfE83332	rogid:SFk8FM1xo7SkodsiFXZYzTbLrYg10090	rigid:UXuqcD71Fp2ugsMaXfoz6vt3pmc	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P71619	uniprotkb:Q8K245	intact:EBI-25767582|uniprotkb:F2GLA0|uniprotkb:I6YAD4	intact:EBI-6678333|ensembl:ENSMUSP00000045297|intact:EBI-10689401|uniprotkb:Q8BVI8|uniprotkb:Q8C0K8	psi-mi:p71619_myctu(display_long)|uniprotkb:ugpB(gene name)|psi-mi:ugpB(display_short)|uniprotkb:Rv2833c(locus name)	psi-mi:uvrag_mouse(display_long)|uniprotkb:Uvrag1(gene name synonym)|uniprotkb:Uvrag(gene name)|psi-mi:Uvrag(display_short)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2018)	doi:10.1093/nar/gkx1173|imex:IM-28235|pubmed:29165646	taxid:83332(myctu)|taxid:83332("Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)")	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0471"(MINT)	intact:EBI-25768766|imex:IM-28235-259	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	go:"GO:0005886"(plasma membrane)|rcsb pdb:6R1B|mint:P71619|refseq:NP_217349.1|refseq:WP_003414501.1|interpro:IPR006059(Bacterial extracellular solute-binding, family 1)|interpro:IPR006311(Twin-arginine translocation pathway signal)	ensembl:ENSMUSG00000035354(gene)|ensembl:ENSMUST00000037968(transcript)|go:"GO:0000149"(SNARE binding)|go:"GO:0000323"(lytic vacuole)|go:"GO:0000421"(autophagosome membrane)|go:"GO:0000775"(chromosome, centromeric region)|go:"GO:0005764"(lysosome)|go:"GO:0005768"(endosome)|go:"GO:0005769"(early endosome)|go:"GO:0005770"(late endosome)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005813"(centrosome)|go:"GO:0006281"(DNA repair)|go:"GO:0006890"(retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum)|go:"GO:0006914"(autophagy)|go:"GO:0007051"(spindle organization)|go:"GO:0007059"(chromosome segregation)|go:"GO:0007098"(centrosome cycle)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0030496"(midbody)|go:"GO:0032465"(regulation of cytokinesis)|go:"GO:0032801"(receptor catabolic process)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035493"(SNARE complex assembly)|go:"GO:0045335"(phagocytic vesicle)|go:"GO:0046718"(viral entry into host cell)|go:"GO:0051684"(maintenance of Golgi location)|go:"GO:0070418"(DNA-dependent protein kinase complex)|go:"GO:0071900"(regulation of protein serine/threonine kinase activity)|go:"GO:0097352"(autophagosome maturation)|go:"GO:0097680"(double-strand break repair via classical nonhomologous end joining)|interpro:IPR000008(C2 calcium-dependent membrane targeting)|interpro:IPR018791|interpro:IPR035892|mint:Q8K245|rcsb pdb:5YR0|reactome:R-MMU-1632852|refseq:NP_848750.3	-	-	-	figure legend:ST5|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2020/07/08	2020/08/14	rogid:ldo4FA/3ddzSo1mfnNEPte27F1083332	rogid:rzFzOhdqb0elqRBuF+JOh7I3AsI10090	rigid:AeFqgaPk11nzoxSKxptnzZqtCdQ	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:O69689	uniprotkb:Q9QY01	intact:EBI-25767781|uniprotkb:F2GFU4|uniprotkb:I6Y4D4|uniprotkb:Q7D501	intact:EBI-11658106|uniprotkb:Q80TV7|uniprotkb:Q9WTP4|ensembl:ENSMUSP00000004920	psi-mi:aspat_myctu(display_long)|uniprotkb:Rv3722c(locus name)	psi-mi:ulk2_mouse(display_long)|uniprotkb:Ulk2(gene name)|psi-mi:Ulk2(display_short)|uniprotkb:Kiaa0623(gene name synonym)|uniprotkb:Serine/threonine-protein kinase Unc51.2(gene name synonym)|uniprotkb:Unc-51-like kinase 2(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2018)	doi:10.1093/nar/gkx1173|imex:IM-28235|pubmed:29165646	taxid:83332(myctu)|taxid:83332("Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)")	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0471"(MINT)	intact:EBI-25768760|imex:IM-28235-31	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	go:"GO:0004069"("L-aspartate:2-oxoglutarate aminotransferase activity")|go:"GO:0005576"(extracellular region)|rcsb pdb:5C6U|rcsb pdb:6U78|rcsb pdb:6U7A|mint:O69689|refseq:NP_218239.2|refseq:WP_003899653.1|interpro:IPR024551|interpro:IPR015424(Pyridoxal phosphate-dependent transferase, major region)|interpro:IPR015422(Pyridoxal phosphate-dependent transferase, major region, subdomain 2)|interpro:IPR015421(Pyridoxal phosphate-dependent transferase, major region, subdomain 1)	refseq:NP_038909.3|ensembl:ENSMUSG00000004798(gene)|ensembl:ENSMUST00000004920(transcript)|go:"GO:0000045"(autophagosome assembly)|go:"GO:0000422"(autophagy of mitochondrion)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0006914"(autophagy)|go:"GO:0007165"(signal transduction)|go:"GO:0018105"(peptidyl-serine phosphorylation)|go:"GO:0030659"(cytoplasmic vesicle membrane)|go:"GO:0034045"(phagophore assembly site membrane)|go:"GO:0034727"(piecemeal microautophagy of the nucleus)|go:"GO:0042594"(response to starvation)|go:"GO:0044805"(late nucleophagy)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0048671"(negative regulation of collateral sprouting)|go:"GO:0048675"(axon extension)|go:"GO:0061709"(reticulophagy)|go:"GO:0075044"(positive regulation by symbiont of host autophagy)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR016237(Serine/threonine-protein kinase, Ulk1/Ulk2)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR022708|mint:Q9QY01|dip:DIP-60901N	-	-	-	figure legend:ST5|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2020/07/08	2020/08/14	rogid:TGWnUCrIwLrRrMnna5+/w33GpgA83332	rogid:FVxLbt6BcjnydbMtYKJKIDCc6So10090	rigid:K9gnBYFFkIxqx8vAx09tcSPd6ik	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:O50440	uniprotkb:Q9QY01	intact:EBI-25767742|uniprotkb:I6XXB2|uniprotkb:L0T7J5	intact:EBI-11658106|uniprotkb:Q80TV7|uniprotkb:Q9WTP4|ensembl:ENSMUSP00000004920	psi-mi:chp2_myctu(display_long)|uniprotkb:chp2(gene name)|psi-mi:chp2(display_short)|uniprotkb:LH57_06500(orf name)|uniprotkb:P425_01234(orf name)|uniprotkb:Rv1184c(locus name)|uniprotkb:RVBD_1184c(locus name)	psi-mi:ulk2_mouse(display_long)|uniprotkb:Ulk2(gene name)|psi-mi:Ulk2(display_short)|uniprotkb:Kiaa0623(gene name synonym)|uniprotkb:Serine/threonine-protein kinase Unc51.2(gene name synonym)|uniprotkb:Unc-51-like kinase 2(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2018)	doi:10.1093/nar/gkx1173|imex:IM-28235|pubmed:29165646	taxid:83332(myctu)|taxid:83332("Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)")	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0471"(MINT)	intact:EBI-25768754|imex:IM-28235-177	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	go:"GO:0005886"(plasma membrane)|go:"GO:0006629"(lipid metabolic process)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016746"(acyltransferase activity)|go:"GO:0005618"(cell wall)|mint:O50440|refseq:NP_215700.1|refseq:WP_003406195.1|interpro:IPR013228(PE-PPE, C-terminal)	refseq:NP_038909.3|ensembl:ENSMUSG00000004798(gene)|ensembl:ENSMUST00000004920(transcript)|go:"GO:0000045"(autophagosome assembly)|go:"GO:0000422"(autophagy of mitochondrion)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0006914"(autophagy)|go:"GO:0007165"(signal transduction)|go:"GO:0018105"(peptidyl-serine phosphorylation)|go:"GO:0030659"(cytoplasmic vesicle membrane)|go:"GO:0034045"(phagophore assembly site membrane)|go:"GO:0034727"(piecemeal microautophagy of the nucleus)|go:"GO:0042594"(response to starvation)|go:"GO:0044805"(late nucleophagy)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0048671"(negative regulation of collateral sprouting)|go:"GO:0048675"(axon extension)|go:"GO:0061709"(reticulophagy)|go:"GO:0075044"(positive regulation by symbiont of host autophagy)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR016237(Serine/threonine-protein kinase, Ulk1/Ulk2)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR022708|mint:Q9QY01|dip:DIP-60901N	-	-	-	figure legend:ST5|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2020/07/08	2020/08/14	rogid:IXzYfb7UxFgqBXPZ6NZHLy3hdTc83332	rogid:FVxLbt6BcjnydbMtYKJKIDCc6So10090	rigid:4gh4hXDuOPdpS11YlentTIcilIs	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:O07422	uniprotkb:Q9QY01	intact:EBI-25767563|uniprotkb:F2GLX6|uniprotkb:I6Y302|uniprotkb:Q7DAB9	intact:EBI-11658106|uniprotkb:Q80TV7|uniprotkb:Q9WTP4|ensembl:ENSMUSP00000004920	psi-mi:o07422_myctu(display_long)|uniprotkb:Rv0178(locus name)	psi-mi:ulk2_mouse(display_long)|uniprotkb:Ulk2(gene name)|psi-mi:Ulk2(display_short)|uniprotkb:Kiaa0623(gene name synonym)|uniprotkb:Serine/threonine-protein kinase Unc51.2(gene name synonym)|uniprotkb:Unc-51-like kinase 2(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2018)	doi:10.1093/nar/gkx1173|imex:IM-28235|pubmed:29165646	taxid:83332(myctu)|taxid:83332("Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)")	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0471"(MINT)	intact:EBI-25768748|imex:IM-28235-295	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	go:"GO:0005576"(extracellular region)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0051701"(biological process involved in interaction with host)|mint:O07422|refseq:NP_214692.1|refseq:WP_003899844.1	refseq:NP_038909.3|ensembl:ENSMUSG00000004798(gene)|ensembl:ENSMUST00000004920(transcript)|go:"GO:0000045"(autophagosome assembly)|go:"GO:0000422"(autophagy of mitochondrion)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0006914"(autophagy)|go:"GO:0007165"(signal transduction)|go:"GO:0018105"(peptidyl-serine phosphorylation)|go:"GO:0030659"(cytoplasmic vesicle membrane)|go:"GO:0034045"(phagophore assembly site membrane)|go:"GO:0034727"(piecemeal microautophagy of the nucleus)|go:"GO:0042594"(response to starvation)|go:"GO:0044805"(late nucleophagy)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0048671"(negative regulation of collateral sprouting)|go:"GO:0048675"(axon extension)|go:"GO:0061709"(reticulophagy)|go:"GO:0075044"(positive regulation by symbiont of host autophagy)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR016237(Serine/threonine-protein kinase, Ulk1/Ulk2)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR022708|mint:Q9QY01|dip:DIP-60901N	-	-	-	figure legend:ST5|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2020/07/08	2020/08/14	rogid:lGOg72Osvz8819m674JzGUcHEj483332	rogid:FVxLbt6BcjnydbMtYKJKIDCc6So10090	rigid:KNOtOOS8xGaUUk502KQAK6Fw4KI	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P9WJB9	uniprotkb:Q9QY01	intact:EBI-25767670|uniprotkb:L0TE21|uniprotkb:O69744|uniprotkb:Q7D4P0	intact:EBI-11658106|uniprotkb:Q80TV7|uniprotkb:Q9WTP4|ensembl:ENSMUSP00000004920	psi-mi:espl_myctu(display_long)|uniprotkb:espL(gene name)|psi-mi:espL(display_short)|uniprotkb:Rv3880c(locus name)	psi-mi:ulk2_mouse(display_long)|uniprotkb:Ulk2(gene name)|psi-mi:Ulk2(display_short)|uniprotkb:Kiaa0623(gene name synonym)|uniprotkb:Serine/threonine-protein kinase Unc51.2(gene name synonym)|uniprotkb:Unc-51-like kinase 2(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2018)	doi:10.1093/nar/gkx1173|imex:IM-28235|pubmed:29165646	taxid:83332(myctu)|taxid:83332("Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)")	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0471"(MINT)	intact:EBI-25768742|imex:IM-28235-29	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	go:"GO:0003677"(DNA binding)|go:"GO:0005618"(cell wall)|go:"GO:0005886"(plasma membrane)|go:"GO:0052170"(suppression by symbiont of host innate immune response)|mint:P9WJB9|refseq:NP_218397.1|refseq:WP_003399988.1|interpro:IPR036894|interpro:IPR004401(Conserved hypothetical protein CHP00103)	refseq:NP_038909.3|ensembl:ENSMUSG00000004798(gene)|ensembl:ENSMUST00000004920(transcript)|go:"GO:0000045"(autophagosome assembly)|go:"GO:0000422"(autophagy of mitochondrion)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0006914"(autophagy)|go:"GO:0007165"(signal transduction)|go:"GO:0018105"(peptidyl-serine phosphorylation)|go:"GO:0030659"(cytoplasmic vesicle membrane)|go:"GO:0034045"(phagophore assembly site membrane)|go:"GO:0034727"(piecemeal microautophagy of the nucleus)|go:"GO:0042594"(response to starvation)|go:"GO:0044805"(late nucleophagy)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0048671"(negative regulation of collateral sprouting)|go:"GO:0048675"(axon extension)|go:"GO:0061709"(reticulophagy)|go:"GO:0075044"(positive regulation by symbiont of host autophagy)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR016237(Serine/threonine-protein kinase, Ulk1/Ulk2)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR022708|mint:Q9QY01|dip:DIP-60901N	-	-	-	figure legend:ST5|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2020/07/08	2020/08/14	rogid:BspTx2RZuhJaQ319NBDIyOreqfE83332	rogid:FVxLbt6BcjnydbMtYKJKIDCc6So10090	rigid:Uo6IY4JcXT18Grw5tw21MUftLms	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P9WIT1	uniprotkb:Q9QY01	intact:EBI-25767539|uniprotkb:L0TBU2|uniprotkb:Q50685|uniprotkb:Q7D7C5	intact:EBI-11658106|uniprotkb:Q80TV7|uniprotkb:Q9WTP4|ensembl:ENSMUSP00000004920	psi-mi:y2280_myctu(display_long)|uniprotkb:Rv2280(locus name)	psi-mi:ulk2_mouse(display_long)|uniprotkb:Ulk2(gene name)|psi-mi:Ulk2(display_short)|uniprotkb:Kiaa0623(gene name synonym)|uniprotkb:Serine/threonine-protein kinase Unc51.2(gene name synonym)|uniprotkb:Unc-51-like kinase 2(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2018)	doi:10.1093/nar/gkx1173|imex:IM-28235|pubmed:29165646	taxid:83332(myctu)|taxid:83332("Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)")	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0471"(MINT)	intact:EBI-25768736|imex:IM-28235-293	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	go:"GO:0005618"(cell wall)|go:"GO:0005886"(plasma membrane)|go:"GO:0016491"(oxidoreductase activity)|go:"GO:0071949"(FAD binding)|interpro:IPR016169(CO dehydrogenase flavoprotein-like, FAD-binding, subdomain 2)|mint:P9WIT1|refseq:WP_003411690.1|interpro:IPR016166(FAD-binding, type 2)|interpro:IPR036318|interpro:IPR016164(FAD-linked oxidase-like, C-terminal)|interpro:IPR004113(FAD-linked oxidase, C-terminal)|interpro:IPR006094(FAD linked oxidase, N-terminal)|interpro:IPR016171(Vanillyl-alcohol oxidase, C-terminal subdomain 2)	refseq:NP_038909.3|ensembl:ENSMUSG00000004798(gene)|ensembl:ENSMUST00000004920(transcript)|go:"GO:0000045"(autophagosome assembly)|go:"GO:0000422"(autophagy of mitochondrion)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0006914"(autophagy)|go:"GO:0007165"(signal transduction)|go:"GO:0018105"(peptidyl-serine phosphorylation)|go:"GO:0030659"(cytoplasmic vesicle membrane)|go:"GO:0034045"(phagophore assembly site membrane)|go:"GO:0034727"(piecemeal microautophagy of the nucleus)|go:"GO:0042594"(response to starvation)|go:"GO:0044805"(late nucleophagy)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0048671"(negative regulation of collateral sprouting)|go:"GO:0048675"(axon extension)|go:"GO:0061709"(reticulophagy)|go:"GO:0075044"(positive regulation by symbiont of host autophagy)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR016237(Serine/threonine-protein kinase, Ulk1/Ulk2)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR022708|mint:Q9QY01|dip:DIP-60901N	-	-	-	figure legend:ST5|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2020/07/08	2020/08/14	rogid:TvFI3uuw9zREl1q0DeWIsHmCSEk83332	rogid:FVxLbt6BcjnydbMtYKJKIDCc6So10090	rigid:1p7QrY2IpqdlS3AlNl2ElaoiXI4	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:O07177	uniprotkb:Q9QY01	intact:EBI-25767633|uniprotkb:L0T5L4	intact:EBI-11658106|uniprotkb:Q80TV7|uniprotkb:Q9WTP4|ensembl:ENSMUSP00000004920	psi-mi:mak1_myctu(display_long)|uniprotkb:mak(gene name)|psi-mi:mak(display_short)|uniprotkb:Maltose-1-phosphate synthase(gene name synonym)|uniprotkb:Rv0127(locus name)	psi-mi:ulk2_mouse(display_long)|uniprotkb:Ulk2(gene name)|psi-mi:Ulk2(display_short)|uniprotkb:Kiaa0623(gene name synonym)|uniprotkb:Serine/threonine-protein kinase Unc51.2(gene name synonym)|uniprotkb:Unc-51-like kinase 2(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2018)	doi:10.1093/nar/gkx1173|imex:IM-28235|pubmed:29165646	taxid:83332(myctu)|taxid:83332("Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)")	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0471"(MINT)	intact:EBI-25768730|imex:IM-28235-291	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	go:"GO:0005978"(glycogen biosynthetic process)|go:"GO:0005992"(trehalose biosynthetic process)|go:"GO:0016301"(kinase activity)|go:"GO:0046835"(carbohydrate phosphorylation)|rcsb pdb:4O7O|rcsb pdb:4O7P|go:"GO:0005524"(ATP binding)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|mint:O07177|refseq:NP_214641.1|refseq:WP_003916610.1|interpro:IPR011009(Protein kinase-like)|interpro:IPR040999	refseq:NP_038909.3|ensembl:ENSMUSG00000004798(gene)|ensembl:ENSMUST00000004920(transcript)|go:"GO:0000045"(autophagosome assembly)|go:"GO:0000422"(autophagy of mitochondrion)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0006914"(autophagy)|go:"GO:0007165"(signal transduction)|go:"GO:0018105"(peptidyl-serine phosphorylation)|go:"GO:0030659"(cytoplasmic vesicle membrane)|go:"GO:0034045"(phagophore assembly site membrane)|go:"GO:0034727"(piecemeal microautophagy of the nucleus)|go:"GO:0042594"(response to starvation)|go:"GO:0044805"(late nucleophagy)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0048671"(negative regulation of collateral sprouting)|go:"GO:0048675"(axon extension)|go:"GO:0061709"(reticulophagy)|go:"GO:0075044"(positive regulation by symbiont of host autophagy)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR016237(Serine/threonine-protein kinase, Ulk1/Ulk2)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR022708|mint:Q9QY01|dip:DIP-60901N	-	-	-	figure legend:ST5|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2020/07/08	2020/08/14	rogid:kpl6jZ4UbJUq/kfAlHBYpJAJV4E83332	rogid:FVxLbt6BcjnydbMtYKJKIDCc6So10090	rigid:dvs4YecMM27LxZNmUGdG+jSFKWA	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P9WN37	uniprotkb:Q9QY01	intact:EBI-25767601|uniprotkb:L0T968|uniprotkb:P64245|uniprotkb:Q10378	intact:EBI-11658106|uniprotkb:Q80TV7|uniprotkb:Q9WTP4|ensembl:ENSMUSP00000004920	psi-mi:gln1a_myctu(display_long)|uniprotkb:glnA2(gene name)|psi-mi:glnA2(display_short)|uniprotkb:Glutamate--ammonia ligase(gene name synonym)|uniprotkb:Glutamine synthetase I alpha(gene name synonym)|uniprotkb:MTCY190.33c(orf name)|uniprotkb:MTCY427.03c(orf name)|uniprotkb:Rv2222c(locus name)	psi-mi:ulk2_mouse(display_long)|uniprotkb:Ulk2(gene name)|psi-mi:Ulk2(display_short)|uniprotkb:Kiaa0623(gene name synonym)|uniprotkb:Serine/threonine-protein kinase Unc51.2(gene name synonym)|uniprotkb:Unc-51-like kinase 2(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2018)	doi:10.1093/nar/gkx1173|imex:IM-28235|pubmed:29165646	taxid:83332(myctu)|taxid:83332("Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)")	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0471"(MINT)	intact:EBI-25768724|imex:IM-28235-175	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	go:"GO:0004356"(glutamate-ammonia ligase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0006542"(glutamine biosynthetic process)|go:"GO:0046872"(metal ion binding)|go:"GO:0050001"(D-glutaminase activity)|mint:P9WN37|refseq:NP_216738.1|refseq:WP_003411482.1|interpro:IPR008147(Glutamine synthetase, beta-Grasp)|interpro:IPR036651|interpro:IPR014746(Glutamine synthetase/guanido kinase, catalytic region)|interpro:IPR008146(Glutamine synthetase, catalytic region)|interpro:IPR027303	refseq:NP_038909.3|ensembl:ENSMUSG00000004798(gene)|ensembl:ENSMUST00000004920(transcript)|go:"GO:0000045"(autophagosome assembly)|go:"GO:0000422"(autophagy of mitochondrion)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0006914"(autophagy)|go:"GO:0007165"(signal transduction)|go:"GO:0018105"(peptidyl-serine phosphorylation)|go:"GO:0030659"(cytoplasmic vesicle membrane)|go:"GO:0034045"(phagophore assembly site membrane)|go:"GO:0034727"(piecemeal microautophagy of the nucleus)|go:"GO:0042594"(response to starvation)|go:"GO:0044805"(late nucleophagy)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0048671"(negative regulation of collateral sprouting)|go:"GO:0048675"(axon extension)|go:"GO:0061709"(reticulophagy)|go:"GO:0075044"(positive regulation by symbiont of host autophagy)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR016237(Serine/threonine-protein kinase, Ulk1/Ulk2)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR022708|mint:Q9QY01|dip:DIP-60901N	-	-	-	figure legend:ST5|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2020/07/08	2020/08/14	rogid:LDIpolmw5yhv2iG5+8HKbWlwT8883332	rogid:FVxLbt6BcjnydbMtYKJKIDCc6So10090	rigid:9RdPdcJaCvynqRhuzpOdsy531gU	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P71619	uniprotkb:Q9QY01	intact:EBI-25767582|uniprotkb:F2GLA0|uniprotkb:I6YAD4	intact:EBI-11658106|uniprotkb:Q80TV7|uniprotkb:Q9WTP4|ensembl:ENSMUSP00000004920	psi-mi:p71619_myctu(display_long)|uniprotkb:ugpB(gene name)|psi-mi:ugpB(display_short)|uniprotkb:Rv2833c(locus name)	psi-mi:ulk2_mouse(display_long)|uniprotkb:Ulk2(gene name)|psi-mi:Ulk2(display_short)|uniprotkb:Kiaa0623(gene name synonym)|uniprotkb:Serine/threonine-protein kinase Unc51.2(gene name synonym)|uniprotkb:Unc-51-like kinase 2(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2018)	doi:10.1093/nar/gkx1173|imex:IM-28235|pubmed:29165646	taxid:83332(myctu)|taxid:83332("Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)")	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0471"(MINT)	intact:EBI-25768718|imex:IM-28235-341	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	go:"GO:0005886"(plasma membrane)|rcsb pdb:6R1B|mint:P71619|refseq:NP_217349.1|refseq:WP_003414501.1|interpro:IPR006059(Bacterial extracellular solute-binding, family 1)|interpro:IPR006311(Twin-arginine translocation pathway signal)	refseq:NP_038909.3|ensembl:ENSMUSG00000004798(gene)|ensembl:ENSMUST00000004920(transcript)|go:"GO:0000045"(autophagosome assembly)|go:"GO:0000422"(autophagy of mitochondrion)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0006914"(autophagy)|go:"GO:0007165"(signal transduction)|go:"GO:0018105"(peptidyl-serine phosphorylation)|go:"GO:0030659"(cytoplasmic vesicle membrane)|go:"GO:0034045"(phagophore assembly site membrane)|go:"GO:0034727"(piecemeal microautophagy of the nucleus)|go:"GO:0042594"(response to starvation)|go:"GO:0044805"(late nucleophagy)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0048671"(negative regulation of collateral sprouting)|go:"GO:0048675"(axon extension)|go:"GO:0061709"(reticulophagy)|go:"GO:0075044"(positive regulation by symbiont of host autophagy)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR016237(Serine/threonine-protein kinase, Ulk1/Ulk2)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR022708|mint:Q9QY01|dip:DIP-60901N	-	-	-	figure legend:ST5|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2020/07/08	2020/08/14	rogid:ldo4FA/3ddzSo1mfnNEPte27F1083332	rogid:FVxLbt6BcjnydbMtYKJKIDCc6So10090	rigid:MRQvlsv7lTpnNONj51WARJBC02g	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:O70405	uniprotkb:O69689	intact:EBI-8390771|intact:UNK-5365168|uniprotkb:Q6PGB2	intact:EBI-25767781|uniprotkb:F2GFU4|uniprotkb:I6Y4D4|uniprotkb:Q7D501	psi-mi:ulk1_mouse(display_long)|uniprotkb:Ulk1(gene name)|psi-mi:Ulk1(display_short)|uniprotkb:Unc-51-like kinase 1(gene name synonym)|uniprotkb:Serine/threonine-protein kinase Unc51.1(gene name synonym)	psi-mi:aspat_myctu(display_long)|uniprotkb:Rv3722c(locus name)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2018)	doi:10.1093/nar/gkx1173|imex:IM-28235|pubmed:29165646	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:83332(myctu)|taxid:83332("Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)")	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0471"(MINT)	intact:EBI-25768712|imex:IM-28235-173	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_033495.2|dip:DIP-60541N|mint:O70405|go:"GO:0000045"(autophagosome assembly)|go:"GO:0000407"(phagophore assembly site)|go:"GO:0000422"(autophagy of mitochondrion)|go:"GO:0000423"(mitophagy)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005776"(autophagosome)|go:"GO:0005829"(cytosol)|go:"GO:0006914"(autophagy)|go:"GO:0007265"(Ras protein signal transduction)|go:"GO:0007409"(axonogenesis)|go:"GO:0008104"(protein localization)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0010508"(positive regulation of autophagy)|go:"GO:0010941"(regulation of cell death)|go:"GO:0016020"(membrane)|go:"GO:0016236"(macroautophagy)|go:"GO:0018105"(peptidyl-serine phosphorylation)|go:"GO:0018107"(peptidyl-threonine phosphorylation)|go:"GO:0019901"(protein kinase binding)|go:"GO:0021707"(cerebellar granule cell differentiation)|go:"GO:0021933"(radial glia guided migration of cerebellar granule cell)|go:"GO:0030424"(axon)|go:"GO:0030659"(cytoplasmic vesicle membrane)|go:"GO:0031102"(neuron projection regeneration)|go:"GO:0031175"(neuron projection development)|go:"GO:0031267"(small GTPase binding)|go:"GO:0031333"(negative regulation of protein-containing complex assembly)|go:"GO:0031623"(receptor internalization)|go:"GO:0031669"(cellular response to nutrient levels)|go:"GO:0034045"(phagophore assembly site membrane)|go:"GO:0034198"(cellular response to amino acid starvation)|go:"GO:0034727"(piecemeal microautophagy of the nucleus)|go:"GO:0042594"(response to starvation)|go:"GO:0042802"(identical protein binding)|go:"GO:0043005"(neuron projection)|go:"GO:0043025"(neuronal cell body)|go:"GO:0044805"(late nucleophagy)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0048671"(negative regulation of collateral sprouting)|go:"GO:0048675"(axon extension)|go:"GO:0051020"(GTPase binding)|go:"GO:0051386"(regulation of neurotrophin TRK receptor signaling pathway)|go:"GO:0051879"(Hsp90 protein binding)|go:"GO:0061709"(reticulophagy)|go:"GO:0075044"(positive regulation by symbiont of host autophagy)|go:"GO:0097629"(extrinsic component of omegasome membrane)|go:"GO:0097632"(extrinsic component of phagophore assembly site membrane)|go:"GO:0097635"(extrinsic component of autophagosome membrane)|go:"GO:0098780"(response to mitochondrial depolarisation)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:1990316"(Atg1/ULK1 kinase complex)|go:"GO:2000786"(positive regulation of autophagosome assembly)|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR016237(Serine/threonine-protein kinase, Ulk1/Ulk2)|interpro:IPR022708|reactome:R-MMU-1632852|reactome:R-MMU-8854214|reactome:R-MMU-8876198|reactome:R-MMU-8934903|interpro:IPR017441(Protein kinase ATP binding, conserved site)	go:"GO:0004069"("L-aspartate:2-oxoglutarate aminotransferase activity")|go:"GO:0005576"(extracellular region)|rcsb pdb:5C6U|rcsb pdb:6U78|rcsb pdb:6U7A|mint:O69689|refseq:NP_218239.2|refseq:WP_003899653.1|interpro:IPR024551|interpro:IPR015424(Pyridoxal phosphate-dependent transferase, major region)|interpro:IPR015422(Pyridoxal phosphate-dependent transferase, major region, subdomain 2)|interpro:IPR015421(Pyridoxal phosphate-dependent transferase, major region, subdomain 1)	-	comment:mint|comment:homomint|function:Involved in axon growth. Plays an essential role in neurite extension of cerebellar granule cells	-	figure legend:ST5|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2020/07/08	2020/08/14	rogid:mLPj6Pp1VXGMixWyd7MygI4VgPo10090	rogid:TGWnUCrIwLrRrMnna5+/w33GpgA83332	rigid:vo5E1iINgEjIrTzeDjdLfLgP9Dk	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:O70405	uniprotkb:O50440	intact:EBI-8390771|intact:UNK-5365168|uniprotkb:Q6PGB2	intact:EBI-25767742|uniprotkb:I6XXB2|uniprotkb:L0T7J5	psi-mi:ulk1_mouse(display_long)|uniprotkb:Ulk1(gene name)|psi-mi:Ulk1(display_short)|uniprotkb:Unc-51-like kinase 1(gene name synonym)|uniprotkb:Serine/threonine-protein kinase Unc51.1(gene name synonym)	psi-mi:chp2_myctu(display_long)|uniprotkb:chp2(gene name)|psi-mi:chp2(display_short)|uniprotkb:LH57_06500(orf name)|uniprotkb:P425_01234(orf name)|uniprotkb:Rv1184c(locus name)|uniprotkb:RVBD_1184c(locus name)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2018)	doi:10.1093/nar/gkx1173|imex:IM-28235|pubmed:29165646	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:83332(myctu)|taxid:83332("Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)")	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0471"(MINT)	intact:EBI-25768706|imex:IM-28235-171	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_033495.2|dip:DIP-60541N|mint:O70405|go:"GO:0000045"(autophagosome assembly)|go:"GO:0000407"(phagophore assembly site)|go:"GO:0000422"(autophagy of mitochondrion)|go:"GO:0000423"(mitophagy)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005776"(autophagosome)|go:"GO:0005829"(cytosol)|go:"GO:0006914"(autophagy)|go:"GO:0007265"(Ras protein signal transduction)|go:"GO:0007409"(axonogenesis)|go:"GO:0008104"(protein localization)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0010508"(positive regulation of autophagy)|go:"GO:0010941"(regulation of cell death)|go:"GO:0016020"(membrane)|go:"GO:0016236"(macroautophagy)|go:"GO:0018105"(peptidyl-serine phosphorylation)|go:"GO:0018107"(peptidyl-threonine phosphorylation)|go:"GO:0019901"(protein kinase binding)|go:"GO:0021707"(cerebellar granule cell differentiation)|go:"GO:0021933"(radial glia guided migration of cerebellar granule cell)|go:"GO:0030424"(axon)|go:"GO:0030659"(cytoplasmic vesicle membrane)|go:"GO:0031102"(neuron projection regeneration)|go:"GO:0031175"(neuron projection development)|go:"GO:0031267"(small GTPase binding)|go:"GO:0031333"(negative regulation of protein-containing complex assembly)|go:"GO:0031623"(receptor internalization)|go:"GO:0031669"(cellular response to nutrient levels)|go:"GO:0034045"(phagophore assembly site membrane)|go:"GO:0034198"(cellular response to amino acid starvation)|go:"GO:0034727"(piecemeal microautophagy of the nucleus)|go:"GO:0042594"(response to starvation)|go:"GO:0042802"(identical protein binding)|go:"GO:0043005"(neuron projection)|go:"GO:0043025"(neuronal cell body)|go:"GO:0044805"(late nucleophagy)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0048671"(negative regulation of collateral sprouting)|go:"GO:0048675"(axon extension)|go:"GO:0051020"(GTPase binding)|go:"GO:0051386"(regulation of neurotrophin TRK receptor signaling pathway)|go:"GO:0051879"(Hsp90 protein binding)|go:"GO:0061709"(reticulophagy)|go:"GO:0075044"(positive regulation by symbiont of host autophagy)|go:"GO:0097629"(extrinsic component of omegasome membrane)|go:"GO:0097632"(extrinsic component of phagophore assembly site membrane)|go:"GO:0097635"(extrinsic component of autophagosome membrane)|go:"GO:0098780"(response to mitochondrial depolarisation)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:1990316"(Atg1/ULK1 kinase complex)|go:"GO:2000786"(positive regulation of autophagosome assembly)|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR016237(Serine/threonine-protein kinase, Ulk1/Ulk2)|interpro:IPR022708|reactome:R-MMU-1632852|reactome:R-MMU-8854214|reactome:R-MMU-8876198|reactome:R-MMU-8934903|interpro:IPR017441(Protein kinase ATP binding, conserved site)	go:"GO:0005886"(plasma membrane)|go:"GO:0006629"(lipid metabolic process)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016746"(acyltransferase activity)|go:"GO:0005618"(cell wall)|mint:O50440|refseq:NP_215700.1|refseq:WP_003406195.1|interpro:IPR013228(PE-PPE, C-terminal)	-	comment:mint|comment:homomint|function:Involved in axon growth. Plays an essential role in neurite extension of cerebellar granule cells	-	figure legend:ST5|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2020/07/08	2020/08/14	rogid:mLPj6Pp1VXGMixWyd7MygI4VgPo10090	rogid:IXzYfb7UxFgqBXPZ6NZHLy3hdTc83332	rigid:6hXuMK37eQJrDY89u9rNPAXiWt4	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:O70405	uniprotkb:O07422	intact:EBI-8390771|intact:UNK-5365168|uniprotkb:Q6PGB2	intact:EBI-25767563|uniprotkb:F2GLX6|uniprotkb:I6Y302|uniprotkb:Q7DAB9	psi-mi:ulk1_mouse(display_long)|uniprotkb:Ulk1(gene name)|psi-mi:Ulk1(display_short)|uniprotkb:Unc-51-like kinase 1(gene name synonym)|uniprotkb:Serine/threonine-protein kinase Unc51.1(gene name synonym)	psi-mi:o07422_myctu(display_long)|uniprotkb:Rv0178(locus name)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2018)	doi:10.1093/nar/gkx1173|imex:IM-28235|pubmed:29165646	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:83332(myctu)|taxid:83332("Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)")	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0471"(MINT)	intact:EBI-25768700|imex:IM-28235-339	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_033495.2|dip:DIP-60541N|mint:O70405|go:"GO:0000045"(autophagosome assembly)|go:"GO:0000407"(phagophore assembly site)|go:"GO:0000422"(autophagy of mitochondrion)|go:"GO:0000423"(mitophagy)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005776"(autophagosome)|go:"GO:0005829"(cytosol)|go:"GO:0006914"(autophagy)|go:"GO:0007265"(Ras protein signal transduction)|go:"GO:0007409"(axonogenesis)|go:"GO:0008104"(protein localization)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0010508"(positive regulation of autophagy)|go:"GO:0010941"(regulation of cell death)|go:"GO:0016020"(membrane)|go:"GO:0016236"(macroautophagy)|go:"GO:0018105"(peptidyl-serine phosphorylation)|go:"GO:0018107"(peptidyl-threonine phosphorylation)|go:"GO:0019901"(protein kinase binding)|go:"GO:0021707"(cerebellar granule cell differentiation)|go:"GO:0021933"(radial glia guided migration of cerebellar granule cell)|go:"GO:0030424"(axon)|go:"GO:0030659"(cytoplasmic vesicle membrane)|go:"GO:0031102"(neuron projection regeneration)|go:"GO:0031175"(neuron projection development)|go:"GO:0031267"(small GTPase binding)|go:"GO:0031333"(negative regulation of protein-containing complex assembly)|go:"GO:0031623"(receptor internalization)|go:"GO:0031669"(cellular response to nutrient levels)|go:"GO:0034045"(phagophore assembly site membrane)|go:"GO:0034198"(cellular response to amino acid starvation)|go:"GO:0034727"(piecemeal microautophagy of the nucleus)|go:"GO:0042594"(response to starvation)|go:"GO:0042802"(identical protein binding)|go:"GO:0043005"(neuron projection)|go:"GO:0043025"(neuronal cell body)|go:"GO:0044805"(late nucleophagy)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0048671"(negative regulation of collateral sprouting)|go:"GO:0048675"(axon extension)|go:"GO:0051020"(GTPase binding)|go:"GO:0051386"(regulation of neurotrophin TRK receptor signaling pathway)|go:"GO:0051879"(Hsp90 protein binding)|go:"GO:0061709"(reticulophagy)|go:"GO:0075044"(positive regulation by symbiont of host autophagy)|go:"GO:0097629"(extrinsic component of omegasome membrane)|go:"GO:0097632"(extrinsic component of phagophore assembly site membrane)|go:"GO:0097635"(extrinsic component of autophagosome membrane)|go:"GO:0098780"(response to mitochondrial depolarisation)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:1990316"(Atg1/ULK1 kinase complex)|go:"GO:2000786"(positive regulation of autophagosome assembly)|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR016237(Serine/threonine-protein kinase, Ulk1/Ulk2)|interpro:IPR022708|reactome:R-MMU-1632852|reactome:R-MMU-8854214|reactome:R-MMU-8876198|reactome:R-MMU-8934903|interpro:IPR017441(Protein kinase ATP binding, conserved site)	go:"GO:0005576"(extracellular region)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0051701"(biological process involved in interaction with host)|mint:O07422|refseq:NP_214692.1|refseq:WP_003899844.1	-	comment:mint|comment:homomint|function:Involved in axon growth. Plays an essential role in neurite extension of cerebellar granule cells	-	figure legend:ST5|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2020/07/08	2020/08/14	rogid:mLPj6Pp1VXGMixWyd7MygI4VgPo10090	rogid:lGOg72Osvz8819m674JzGUcHEj483332	rigid:LMq0cExvP7E8d2AFEb2fNdQ7mb8	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:O70405	uniprotkb:P9WJB9	intact:EBI-8390771|intact:UNK-5365168|uniprotkb:Q6PGB2	intact:EBI-25767670|uniprotkb:L0TE21|uniprotkb:O69744|uniprotkb:Q7D4P0	psi-mi:ulk1_mouse(display_long)|uniprotkb:Ulk1(gene name)|psi-mi:Ulk1(display_short)|uniprotkb:Unc-51-like kinase 1(gene name synonym)|uniprotkb:Serine/threonine-protein kinase Unc51.1(gene name synonym)	psi-mi:espl_myctu(display_long)|uniprotkb:espL(gene name)|psi-mi:espL(display_short)|uniprotkb:Rv3880c(locus name)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2018)	doi:10.1093/nar/gkx1173|imex:IM-28235|pubmed:29165646	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:83332(myctu)|taxid:83332("Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)")	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0471"(MINT)	intact:EBI-25768694|imex:IM-28235-213	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_033495.2|dip:DIP-60541N|mint:O70405|go:"GO:0000045"(autophagosome assembly)|go:"GO:0000407"(phagophore assembly site)|go:"GO:0000422"(autophagy of mitochondrion)|go:"GO:0000423"(mitophagy)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005776"(autophagosome)|go:"GO:0005829"(cytosol)|go:"GO:0006914"(autophagy)|go:"GO:0007265"(Ras protein signal transduction)|go:"GO:0007409"(axonogenesis)|go:"GO:0008104"(protein localization)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0010508"(positive regulation of autophagy)|go:"GO:0010941"(regulation of cell death)|go:"GO:0016020"(membrane)|go:"GO:0016236"(macroautophagy)|go:"GO:0018105"(peptidyl-serine phosphorylation)|go:"GO:0018107"(peptidyl-threonine phosphorylation)|go:"GO:0019901"(protein kinase binding)|go:"GO:0021707"(cerebellar granule cell differentiation)|go:"GO:0021933"(radial glia guided migration of cerebellar granule cell)|go:"GO:0030424"(axon)|go:"GO:0030659"(cytoplasmic vesicle membrane)|go:"GO:0031102"(neuron projection regeneration)|go:"GO:0031175"(neuron projection development)|go:"GO:0031267"(small GTPase binding)|go:"GO:0031333"(negative regulation of protein-containing complex assembly)|go:"GO:0031623"(receptor internalization)|go:"GO:0031669"(cellular response to nutrient levels)|go:"GO:0034045"(phagophore assembly site membrane)|go:"GO:0034198"(cellular response to amino acid starvation)|go:"GO:0034727"(piecemeal microautophagy of the nucleus)|go:"GO:0042594"(response to starvation)|go:"GO:0042802"(identical protein binding)|go:"GO:0043005"(neuron projection)|go:"GO:0043025"(neuronal cell body)|go:"GO:0044805"(late nucleophagy)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0048671"(negative regulation of collateral sprouting)|go:"GO:0048675"(axon extension)|go:"GO:0051020"(GTPase binding)|go:"GO:0051386"(regulation of neurotrophin TRK receptor signaling pathway)|go:"GO:0051879"(Hsp90 protein binding)|go:"GO:0061709"(reticulophagy)|go:"GO:0075044"(positive regulation by symbiont of host autophagy)|go:"GO:0097629"(extrinsic component of omegasome membrane)|go:"GO:0097632"(extrinsic component of phagophore assembly site membrane)|go:"GO:0097635"(extrinsic component of autophagosome membrane)|go:"GO:0098780"(response to mitochondrial depolarisation)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:1990316"(Atg1/ULK1 kinase complex)|go:"GO:2000786"(positive regulation of autophagosome assembly)|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR016237(Serine/threonine-protein kinase, Ulk1/Ulk2)|interpro:IPR022708|reactome:R-MMU-1632852|reactome:R-MMU-8854214|reactome:R-MMU-8876198|reactome:R-MMU-8934903|interpro:IPR017441(Protein kinase ATP binding, conserved site)	go:"GO:0003677"(DNA binding)|go:"GO:0005618"(cell wall)|go:"GO:0005886"(plasma membrane)|go:"GO:0052170"(suppression by symbiont of host innate immune response)|mint:P9WJB9|refseq:NP_218397.1|refseq:WP_003399988.1|interpro:IPR036894|interpro:IPR004401(Conserved hypothetical protein CHP00103)	-	comment:mint|comment:homomint|function:Involved in axon growth. Plays an essential role in neurite extension of cerebellar granule cells	-	figure legend:ST5|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2020/07/08	2020/08/14	rogid:mLPj6Pp1VXGMixWyd7MygI4VgPo10090	rogid:BspTx2RZuhJaQ319NBDIyOreqfE83332	rigid:HEUQ43Vu9zrjGWXbFAZlaKb83k4	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:O70405	uniprotkb:P9WIT1	intact:EBI-8390771|intact:UNK-5365168|uniprotkb:Q6PGB2	intact:EBI-25767539|uniprotkb:L0TBU2|uniprotkb:Q50685|uniprotkb:Q7D7C5	psi-mi:ulk1_mouse(display_long)|uniprotkb:Ulk1(gene name)|psi-mi:Ulk1(display_short)|uniprotkb:Unc-51-like kinase 1(gene name synonym)|uniprotkb:Serine/threonine-protein kinase Unc51.1(gene name synonym)	psi-mi:y2280_myctu(display_long)|uniprotkb:Rv2280(locus name)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2018)	doi:10.1093/nar/gkx1173|imex:IM-28235|pubmed:29165646	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:83332(myctu)|taxid:83332("Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)")	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0471"(MINT)	intact:EBI-25768688|imex:IM-28235-169	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_033495.2|dip:DIP-60541N|mint:O70405|go:"GO:0000045"(autophagosome assembly)|go:"GO:0000407"(phagophore assembly site)|go:"GO:0000422"(autophagy of mitochondrion)|go:"GO:0000423"(mitophagy)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005776"(autophagosome)|go:"GO:0005829"(cytosol)|go:"GO:0006914"(autophagy)|go:"GO:0007265"(Ras protein signal transduction)|go:"GO:0007409"(axonogenesis)|go:"GO:0008104"(protein localization)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0010508"(positive regulation of autophagy)|go:"GO:0010941"(regulation of cell death)|go:"GO:0016020"(membrane)|go:"GO:0016236"(macroautophagy)|go:"GO:0018105"(peptidyl-serine phosphorylation)|go:"GO:0018107"(peptidyl-threonine phosphorylation)|go:"GO:0019901"(protein kinase binding)|go:"GO:0021707"(cerebellar granule cell differentiation)|go:"GO:0021933"(radial glia guided migration of cerebellar granule cell)|go:"GO:0030424"(axon)|go:"GO:0030659"(cytoplasmic vesicle membrane)|go:"GO:0031102"(neuron projection regeneration)|go:"GO:0031175"(neuron projection development)|go:"GO:0031267"(small GTPase binding)|go:"GO:0031333"(negative regulation of protein-containing complex assembly)|go:"GO:0031623"(receptor internalization)|go:"GO:0031669"(cellular response to nutrient levels)|go:"GO:0034045"(phagophore assembly site membrane)|go:"GO:0034198"(cellular response to amino acid starvation)|go:"GO:0034727"(piecemeal microautophagy of the nucleus)|go:"GO:0042594"(response to starvation)|go:"GO:0042802"(identical protein binding)|go:"GO:0043005"(neuron projection)|go:"GO:0043025"(neuronal cell body)|go:"GO:0044805"(late nucleophagy)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0048671"(negative regulation of collateral sprouting)|go:"GO:0048675"(axon extension)|go:"GO:0051020"(GTPase binding)|go:"GO:0051386"(regulation of neurotrophin TRK receptor signaling pathway)|go:"GO:0051879"(Hsp90 protein binding)|go:"GO:0061709"(reticulophagy)|go:"GO:0075044"(positive regulation by symbiont of host autophagy)|go:"GO:0097629"(extrinsic component of omegasome membrane)|go:"GO:0097632"(extrinsic component of phagophore assembly site membrane)|go:"GO:0097635"(extrinsic component of autophagosome membrane)|go:"GO:0098780"(response to mitochondrial depolarisation)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:1990316"(Atg1/ULK1 kinase complex)|go:"GO:2000786"(positive regulation of autophagosome assembly)|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR016237(Serine/threonine-protein kinase, Ulk1/Ulk2)|interpro:IPR022708|reactome:R-MMU-1632852|reactome:R-MMU-8854214|reactome:R-MMU-8876198|reactome:R-MMU-8934903|interpro:IPR017441(Protein kinase ATP binding, conserved site)	go:"GO:0005618"(cell wall)|go:"GO:0005886"(plasma membrane)|go:"GO:0016491"(oxidoreductase activity)|go:"GO:0071949"(FAD binding)|interpro:IPR016169(CO dehydrogenase flavoprotein-like, FAD-binding, subdomain 2)|mint:P9WIT1|refseq:WP_003411690.1|interpro:IPR016166(FAD-binding, type 2)|interpro:IPR036318|interpro:IPR016164(FAD-linked oxidase-like, C-terminal)|interpro:IPR004113(FAD-linked oxidase, C-terminal)|interpro:IPR006094(FAD linked oxidase, N-terminal)|interpro:IPR016171(Vanillyl-alcohol oxidase, C-terminal subdomain 2)	-	comment:mint|comment:homomint|function:Involved in axon growth. Plays an essential role in neurite extension of cerebellar granule cells	-	figure legend:ST5|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2020/07/08	2020/08/14	rogid:mLPj6Pp1VXGMixWyd7MygI4VgPo10090	rogid:TvFI3uuw9zREl1q0DeWIsHmCSEk83332	rigid:EHd0Sm3NfQCjDan75+Tgyrzv8Ko	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:O70405	uniprotkb:O07177	intact:EBI-8390771|intact:UNK-5365168|uniprotkb:Q6PGB2	intact:EBI-25767633|uniprotkb:L0T5L4	psi-mi:ulk1_mouse(display_long)|uniprotkb:Ulk1(gene name)|psi-mi:Ulk1(display_short)|uniprotkb:Unc-51-like kinase 1(gene name synonym)|uniprotkb:Serine/threonine-protein kinase Unc51.1(gene name synonym)	psi-mi:mak1_myctu(display_long)|uniprotkb:mak(gene name)|psi-mi:mak(display_short)|uniprotkb:Maltose-1-phosphate synthase(gene name synonym)|uniprotkb:Rv0127(locus name)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2018)	doi:10.1093/nar/gkx1173|imex:IM-28235|pubmed:29165646	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:83332(myctu)|taxid:83332("Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)")	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0471"(MINT)	intact:EBI-25768682|imex:IM-28235-167	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_033495.2|dip:DIP-60541N|mint:O70405|go:"GO:0000045"(autophagosome assembly)|go:"GO:0000407"(phagophore assembly site)|go:"GO:0000422"(autophagy of mitochondrion)|go:"GO:0000423"(mitophagy)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005776"(autophagosome)|go:"GO:0005829"(cytosol)|go:"GO:0006914"(autophagy)|go:"GO:0007265"(Ras protein signal transduction)|go:"GO:0007409"(axonogenesis)|go:"GO:0008104"(protein localization)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0010508"(positive regulation of autophagy)|go:"GO:0010941"(regulation of cell death)|go:"GO:0016020"(membrane)|go:"GO:0016236"(macroautophagy)|go:"GO:0018105"(peptidyl-serine phosphorylation)|go:"GO:0018107"(peptidyl-threonine phosphorylation)|go:"GO:0019901"(protein kinase binding)|go:"GO:0021707"(cerebellar granule cell differentiation)|go:"GO:0021933"(radial glia guided migration of cerebellar granule cell)|go:"GO:0030424"(axon)|go:"GO:0030659"(cytoplasmic vesicle membrane)|go:"GO:0031102"(neuron projection regeneration)|go:"GO:0031175"(neuron projection development)|go:"GO:0031267"(small GTPase binding)|go:"GO:0031333"(negative regulation of protein-containing complex assembly)|go:"GO:0031623"(receptor internalization)|go:"GO:0031669"(cellular response to nutrient levels)|go:"GO:0034045"(phagophore assembly site membrane)|go:"GO:0034198"(cellular response to amino acid starvation)|go:"GO:0034727"(piecemeal microautophagy of the nucleus)|go:"GO:0042594"(response to starvation)|go:"GO:0042802"(identical protein binding)|go:"GO:0043005"(neuron projection)|go:"GO:0043025"(neuronal cell body)|go:"GO:0044805"(late nucleophagy)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0048671"(negative regulation of collateral sprouting)|go:"GO:0048675"(axon extension)|go:"GO:0051020"(GTPase binding)|go:"GO:0051386"(regulation of neurotrophin TRK receptor signaling pathway)|go:"GO:0051879"(Hsp90 protein binding)|go:"GO:0061709"(reticulophagy)|go:"GO:0075044"(positive regulation by symbiont of host autophagy)|go:"GO:0097629"(extrinsic component of omegasome membrane)|go:"GO:0097632"(extrinsic component of phagophore assembly site membrane)|go:"GO:0097635"(extrinsic component of autophagosome membrane)|go:"GO:0098780"(response to mitochondrial depolarisation)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:1990316"(Atg1/ULK1 kinase complex)|go:"GO:2000786"(positive regulation of autophagosome assembly)|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR016237(Serine/threonine-protein kinase, Ulk1/Ulk2)|interpro:IPR022708|reactome:R-MMU-1632852|reactome:R-MMU-8854214|reactome:R-MMU-8876198|reactome:R-MMU-8934903|interpro:IPR017441(Protein kinase ATP binding, conserved site)	go:"GO:0005978"(glycogen biosynthetic process)|go:"GO:0005992"(trehalose biosynthetic process)|go:"GO:0016301"(kinase activity)|go:"GO:0046835"(carbohydrate phosphorylation)|rcsb pdb:4O7O|rcsb pdb:4O7P|go:"GO:0005524"(ATP binding)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|mint:O07177|refseq:NP_214641.1|refseq:WP_003916610.1|interpro:IPR011009(Protein kinase-like)|interpro:IPR040999	-	comment:mint|comment:homomint|function:Involved in axon growth. Plays an essential role in neurite extension of cerebellar granule cells	-	figure legend:ST5|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2020/07/08	2020/08/14	rogid:mLPj6Pp1VXGMixWyd7MygI4VgPo10090	rogid:kpl6jZ4UbJUq/kfAlHBYpJAJV4E83332	rigid:XcYASEcWNeLWwFXOLgraLKeG4Us	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:O70405	uniprotkb:P9WN37	intact:EBI-8390771|intact:UNK-5365168|uniprotkb:Q6PGB2	intact:EBI-25767601|uniprotkb:L0T968|uniprotkb:P64245|uniprotkb:Q10378	psi-mi:ulk1_mouse(display_long)|uniprotkb:Ulk1(gene name)|psi-mi:Ulk1(display_short)|uniprotkb:Unc-51-like kinase 1(gene name synonym)|uniprotkb:Serine/threonine-protein kinase Unc51.1(gene name synonym)	psi-mi:gln1a_myctu(display_long)|uniprotkb:glnA2(gene name)|psi-mi:glnA2(display_short)|uniprotkb:Glutamate--ammonia ligase(gene name synonym)|uniprotkb:Glutamine synthetase I alpha(gene name synonym)|uniprotkb:MTCY190.33c(orf name)|uniprotkb:MTCY427.03c(orf name)|uniprotkb:Rv2222c(locus name)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2018)	doi:10.1093/nar/gkx1173|imex:IM-28235|pubmed:29165646	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:83332(myctu)|taxid:83332("Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)")	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0471"(MINT)	intact:EBI-25768676|imex:IM-28235-211	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_033495.2|dip:DIP-60541N|mint:O70405|go:"GO:0000045"(autophagosome assembly)|go:"GO:0000407"(phagophore assembly site)|go:"GO:0000422"(autophagy of mitochondrion)|go:"GO:0000423"(mitophagy)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005776"(autophagosome)|go:"GO:0005829"(cytosol)|go:"GO:0006914"(autophagy)|go:"GO:0007265"(Ras protein signal transduction)|go:"GO:0007409"(axonogenesis)|go:"GO:0008104"(protein localization)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0010508"(positive regulation of autophagy)|go:"GO:0010941"(regulation of cell death)|go:"GO:0016020"(membrane)|go:"GO:0016236"(macroautophagy)|go:"GO:0018105"(peptidyl-serine phosphorylation)|go:"GO:0018107"(peptidyl-threonine phosphorylation)|go:"GO:0019901"(protein kinase binding)|go:"GO:0021707"(cerebellar granule cell differentiation)|go:"GO:0021933"(radial glia guided migration of cerebellar granule cell)|go:"GO:0030424"(axon)|go:"GO:0030659"(cytoplasmic vesicle membrane)|go:"GO:0031102"(neuron projection regeneration)|go:"GO:0031175"(neuron projection development)|go:"GO:0031267"(small GTPase binding)|go:"GO:0031333"(negative regulation of protein-containing complex assembly)|go:"GO:0031623"(receptor internalization)|go:"GO:0031669"(cellular response to nutrient levels)|go:"GO:0034045"(phagophore assembly site membrane)|go:"GO:0034198"(cellular response to amino acid starvation)|go:"GO:0034727"(piecemeal microautophagy of the nucleus)|go:"GO:0042594"(response to starvation)|go:"GO:0042802"(identical protein binding)|go:"GO:0043005"(neuron projection)|go:"GO:0043025"(neuronal cell body)|go:"GO:0044805"(late nucleophagy)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0048671"(negative regulation of collateral sprouting)|go:"GO:0048675"(axon extension)|go:"GO:0051020"(GTPase binding)|go:"GO:0051386"(regulation of neurotrophin TRK receptor signaling pathway)|go:"GO:0051879"(Hsp90 protein binding)|go:"GO:0061709"(reticulophagy)|go:"GO:0075044"(positive regulation by symbiont of host autophagy)|go:"GO:0097629"(extrinsic component of omegasome membrane)|go:"GO:0097632"(extrinsic component of phagophore assembly site membrane)|go:"GO:0097635"(extrinsic component of autophagosome membrane)|go:"GO:0098780"(response to mitochondrial depolarisation)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:1990316"(Atg1/ULK1 kinase complex)|go:"GO:2000786"(positive regulation of autophagosome assembly)|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR016237(Serine/threonine-protein kinase, Ulk1/Ulk2)|interpro:IPR022708|reactome:R-MMU-1632852|reactome:R-MMU-8854214|reactome:R-MMU-8876198|reactome:R-MMU-8934903|interpro:IPR017441(Protein kinase ATP binding, conserved site)	go:"GO:0004356"(glutamate-ammonia ligase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0006542"(glutamine biosynthetic process)|go:"GO:0046872"(metal ion binding)|go:"GO:0050001"(D-glutaminase activity)|mint:P9WN37|refseq:NP_216738.1|refseq:WP_003411482.1|interpro:IPR008147(Glutamine synthetase, beta-Grasp)|interpro:IPR036651|interpro:IPR014746(Glutamine synthetase/guanido kinase, catalytic region)|interpro:IPR008146(Glutamine synthetase, catalytic region)|interpro:IPR027303	-	comment:mint|comment:homomint|function:Involved in axon growth. Plays an essential role in neurite extension of cerebellar granule cells	-	figure legend:ST5|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2020/07/08	2020/08/14	rogid:mLPj6Pp1VXGMixWyd7MygI4VgPo10090	rogid:LDIpolmw5yhv2iG5+8HKbWlwT8883332	rigid:w1ucIgwl+fuwxef6/8AAcvnwnbw	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q61037	uniprotkb:O69689	intact:EBI-7924402|uniprotkb:Q61007|uniprotkb:Q61008|uniprotkb:P97724|uniprotkb:P97727|uniprotkb:P97725|intact:MINT-5068541|uniprotkb:Q9WUF6|uniprotkb:P97723	intact:EBI-25767781|uniprotkb:F2GFU4|uniprotkb:I6Y4D4|uniprotkb:Q7D501	psi-mi:tsc2_mouse(display_long)|uniprotkb:Tuberous sclerosis 2 protein homolog(gene name synonym)|uniprotkb:Tsc2(gene name)|psi-mi:Tsc2(display_short)	psi-mi:aspat_myctu(display_long)|uniprotkb:Rv3722c(locus name)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2018)	doi:10.1093/nar/gkx1173|imex:IM-28235|pubmed:29165646	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:83332(myctu)|taxid:83332("Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)")	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0471"(MINT)	intact:EBI-25768670|imex:IM-28235-27	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	interpro:IPR018515|interpro:IPR016024(Armadillo-type fold)|interpro:IPR024584|mint:Q61037|interpro:IPR000331(Rap/ran-GAP)|interpro:IPR003913(Tuberin)|go:"GO:0001666"(response to hypoxia)|go:"GO:0001843"(neural tube closure)|go:"GO:0001933"(negative regulation of protein phosphorylation)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005764"(lysosome)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005901"(caveola)|go:"GO:0006469"(negative regulation of protein kinase activity)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0007165"(signal transduction)|go:"GO:0007507"(heart development)|go:"GO:0007568"(aging)|go:"GO:0008104"(protein localization)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0010508"(positive regulation of autophagy)|go:"GO:0045792"(negative regulation of cell size)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046323"(glucose import)|go:"GO:0046626"(regulation of insulin receptor signaling pathway)|go:"GO:0046627"(negative regulation of insulin receptor signaling pathway)|go:"GO:0047485"(protein N-terminus binding)|go:"GO:0048009"(insulin-like growth factor receptor signaling pathway)|go:"GO:0048147"(negative regulation of fibroblast proliferation)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0048550"(negative regulation of pinocytosis)|go:"GO:0050680"(negative regulation of epithelial cell proliferation)|go:"GO:0050771"(negative regulation of axonogenesis)|go:"GO:0050918"(positive chemotaxis)|go:"GO:0051056"(regulation of small GTPase mediated signal transduction)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0051879"(Hsp90 protein binding)|go:"GO:0051898"(negative regulation of protein kinase B signaling)|go:"GO:0060999"(positive regulation of dendritic spine development)|go:"GO:0071889"(14-3-3 protein binding)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0045785"(positive regulation of cell adhesion)|go:"GO:1904262"(negative regulation of TORC1 signaling)|go:"GO:1905563"(negative regulation of vascular endothelial cell proliferation)|reactome:R-MMU-1632852|reactome:R-MMU-165181|reactome:R-MMU-198323|reactome:R-MMU-380972|reactome:R-MMU-5628897|reactome:R-MMU-8854214|go:"GO:0099175"(regulation of postsynapse organization)|go:"GO:0010763"(positive regulation of fibroblast migration)|go:"GO:0010976"(positive regulation of neuron projection development)|go:"GO:0014065"(phosphatidylinositol 3-kinase signaling)|go:"GO:0014067"(negative regulation of phosphatidylinositol 3-kinase signaling)|go:"GO:0014069"(postsynaptic density)|go:"GO:0016020"(membrane)|go:"GO:0016239"(positive regulation of macroautophagy)|go:"GO:0016242"(negative regulation of macroautophagy)|go:"GO:0019902"(phosphatase binding)|go:"GO:0030010"(establishment of cell polarity)|go:"GO:0030030"(cell projection organization)|go:"GO:0030100"(regulation of endocytosis)|go:"GO:0030178"(negative regulation of Wnt signaling pathway)|go:"GO:0030425"(dendrite)|go:"GO:0010719"(negative regulation of epithelial to mesenchymal transition)|go:"GO:0031267"(small GTPase binding)|go:"GO:0032007"(negative regulation of TOR signaling)|go:"GO:0032869"(cellular response to insulin stimulus)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033596"(TSC1-TSC2 complex)|go:"GO:0034394"(protein localization to cell surface)|go:"GO:0035176"(social behavior)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0042995"(cell projection)|go:"GO:0043005"(neuron projection)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0043276"(anoikis)|go:"GO:0043407"(negative regulation of MAP kinase activity)|go:"GO:0043491"(protein kinase B signaling)|go:"GO:0043547"(positive regulation of GTPase activity)|go:"GO:0044861"(protein transport into plasma membrane raft)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045121"(membrane raft)|go:"GO:0045184"(establishment of protein localization)|go:"GO:0045202"(synapse)|go:"GO:0030426"(growth cone)|interpro:IPR027107|interpro:IPR035974	go:"GO:0004069"("L-aspartate:2-oxoglutarate aminotransferase activity")|go:"GO:0005576"(extracellular region)|rcsb pdb:5C6U|rcsb pdb:6U78|rcsb pdb:6U7A|mint:O69689|refseq:NP_218239.2|refseq:WP_003899653.1|interpro:IPR024551|interpro:IPR015424(Pyridoxal phosphate-dependent transferase, major region)|interpro:IPR015422(Pyridoxal phosphate-dependent transferase, major region, subdomain 2)|interpro:IPR015421(Pyridoxal phosphate-dependent transferase, major region, subdomain 1)	-	function:Implicated as a tumor suppressor. May have a function in vesicular transport, but may also play a role in the regulation of cell growth arrest and in the regulation of transcription mediated by steroid receptors. Interaction between TSC1 and TSC2 may facilitate vesicular docking. Specifically stimulates the intrinsic GTPase activity of the ras-related protein RAP1A and RAB5. Suggesting a possible mechanism for its role in regulating cellular growth|comment:mint	-	figure legend:ST5|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2020/07/08	2020/08/14	rogid:Sw17BM+O0FRiPsuF0+h8V/MedTM10090	rogid:TGWnUCrIwLrRrMnna5+/w33GpgA83332	rigid:YUOgzyI/oLn+zcqaYgjm4NjvkGA	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q61037	uniprotkb:P9WHV1	intact:EBI-7924402|uniprotkb:Q61007|uniprotkb:Q61008|uniprotkb:P97724|uniprotkb:P97727|uniprotkb:P97725|intact:MINT-5068541|uniprotkb:Q9WUF6|uniprotkb:P97723	intact:EBI-25768182|uniprotkb:L0TB68|uniprotkb:P65788|uniprotkb:P71921	psi-mi:tsc2_mouse(display_long)|uniprotkb:Tuberous sclerosis 2 protein homolog(gene name synonym)|uniprotkb:Tsc2(gene name)|psi-mi:Tsc2(display_short)	psi-mi:proa_myctu(display_long)|uniprotkb:proA(gene name)|psi-mi:proA(display_short)|uniprotkb:Glutamate-5-semialdehyde dehydrogenase(gene name synonym)|uniprotkb:Glutamyl-gamma-semialdehyde dehydrogenase(gene name synonym)|uniprotkb:MTCY428.20(orf name)|uniprotkb:Rv2427c(locus name)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2018)	doi:10.1093/nar/gkx1173|imex:IM-28235|pubmed:29165646	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:83332(myctu)|taxid:83332("Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)")	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0471"(MINT)	intact:EBI-25768664|imex:IM-28235-337	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	interpro:IPR018515|interpro:IPR016024(Armadillo-type fold)|interpro:IPR024584|mint:Q61037|interpro:IPR000331(Rap/ran-GAP)|interpro:IPR003913(Tuberin)|go:"GO:0001666"(response to hypoxia)|go:"GO:0001843"(neural tube closure)|go:"GO:0001933"(negative regulation of protein phosphorylation)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005764"(lysosome)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005901"(caveola)|go:"GO:0006469"(negative regulation of protein kinase activity)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0007165"(signal transduction)|go:"GO:0007507"(heart development)|go:"GO:0007568"(aging)|go:"GO:0008104"(protein localization)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0010508"(positive regulation of autophagy)|go:"GO:0045792"(negative regulation of cell size)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046323"(glucose import)|go:"GO:0046626"(regulation of insulin receptor signaling pathway)|go:"GO:0046627"(negative regulation of insulin receptor signaling pathway)|go:"GO:0047485"(protein N-terminus binding)|go:"GO:0048009"(insulin-like growth factor receptor signaling pathway)|go:"GO:0048147"(negative regulation of fibroblast proliferation)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0048550"(negative regulation of pinocytosis)|go:"GO:0050680"(negative regulation of epithelial cell proliferation)|go:"GO:0050771"(negative regulation of axonogenesis)|go:"GO:0050918"(positive chemotaxis)|go:"GO:0051056"(regulation of small GTPase mediated signal transduction)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0051879"(Hsp90 protein binding)|go:"GO:0051898"(negative regulation of protein kinase B signaling)|go:"GO:0060999"(positive regulation of dendritic spine development)|go:"GO:0071889"(14-3-3 protein binding)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0045785"(positive regulation of cell adhesion)|go:"GO:1904262"(negative regulation of TORC1 signaling)|go:"GO:1905563"(negative regulation of vascular endothelial cell proliferation)|reactome:R-MMU-1632852|reactome:R-MMU-165181|reactome:R-MMU-198323|reactome:R-MMU-380972|reactome:R-MMU-5628897|reactome:R-MMU-8854214|go:"GO:0099175"(regulation of postsynapse organization)|go:"GO:0010763"(positive regulation of fibroblast migration)|go:"GO:0010976"(positive regulation of neuron projection development)|go:"GO:0014065"(phosphatidylinositol 3-kinase signaling)|go:"GO:0014067"(negative regulation of phosphatidylinositol 3-kinase signaling)|go:"GO:0014069"(postsynaptic density)|go:"GO:0016020"(membrane)|go:"GO:0016239"(positive regulation of macroautophagy)|go:"GO:0016242"(negative regulation of macroautophagy)|go:"GO:0019902"(phosphatase binding)|go:"GO:0030010"(establishment of cell polarity)|go:"GO:0030030"(cell projection organization)|go:"GO:0030100"(regulation of endocytosis)|go:"GO:0030178"(negative regulation of Wnt signaling pathway)|go:"GO:0030425"(dendrite)|go:"GO:0010719"(negative regulation of epithelial to mesenchymal transition)|go:"GO:0031267"(small GTPase binding)|go:"GO:0032007"(negative regulation of TOR signaling)|go:"GO:0032869"(cellular response to insulin stimulus)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033596"(TSC1-TSC2 complex)|go:"GO:0034394"(protein localization to cell surface)|go:"GO:0035176"(social behavior)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0042995"(cell projection)|go:"GO:0043005"(neuron projection)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0043276"(anoikis)|go:"GO:0043407"(negative regulation of MAP kinase activity)|go:"GO:0043491"(protein kinase B signaling)|go:"GO:0043547"(positive regulation of GTPase activity)|go:"GO:0044861"(protein transport into plasma membrane raft)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045121"(membrane raft)|go:"GO:0045184"(establishment of protein localization)|go:"GO:0045202"(synapse)|go:"GO:0030426"(growth cone)|interpro:IPR027107|interpro:IPR035974	go:"GO:0004350"(glutamate-5-semialdehyde dehydrogenase activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0050661"(NADP binding)|go:"GO:0055129"(L-proline biosynthetic process)|go:"GO:0005829"(cytosol)|mint:P9WHV1|refseq:NP_216943.1|refseq:WP_003412516.1|interpro:IPR016161(Aldehyde/histidinol dehydrogenase)|interpro:IPR016163(Aldehyde dehydrogenase, C-terminal)|interpro:IPR016162(Aldehyde dehydrogenase, N-terminal)|interpro:IPR015590(Aldehyde dehydrogenase)|interpro:IPR020593|interpro:IPR012134(Glutamate-5-semialdehyde dehydrogenase)|interpro:IPR000965(Gamma-glutamyl phosphate reductase GPR)	-	function:Implicated as a tumor suppressor. May have a function in vesicular transport, but may also play a role in the regulation of cell growth arrest and in the regulation of transcription mediated by steroid receptors. Interaction between TSC1 and TSC2 may facilitate vesicular docking. Specifically stimulates the intrinsic GTPase activity of the ras-related protein RAP1A and RAB5. Suggesting a possible mechanism for its role in regulating cellular growth|comment:mint	-	figure legend:ST5|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2020/07/08	2020/08/14	rogid:Sw17BM+O0FRiPsuF0+h8V/MedTM10090	rogid:fzCkUX2wrGj0ZK0LOaeT+UNWpwI83332	rigid:s2gzU0R5JsODai3l4yU9X+sFwP4	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q61037	uniprotkb:O53319	intact:EBI-7924402|uniprotkb:Q61007|uniprotkb:Q61008|uniprotkb:P97724|uniprotkb:P97727|uniprotkb:P97725|intact:MINT-5068541|uniprotkb:Q9WUF6|uniprotkb:P97723	intact:EBI-25767766|uniprotkb:I6X6K2|uniprotkb:L0TEH7	psi-mi:tsc2_mouse(display_long)|uniprotkb:Tuberous sclerosis 2 protein homolog(gene name synonym)|uniprotkb:Tsc2(gene name)|psi-mi:Tsc2(display_short)	psi-mi:o53319_myctu(display_long)|uniprotkb:Rv3169(locus name)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2018)	doi:10.1093/nar/gkx1173|imex:IM-28235|pubmed:29165646	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:83332(myctu)|taxid:83332("Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)")	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0471"(MINT)	intact:EBI-25768658|imex:IM-28235-111	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	interpro:IPR018515|interpro:IPR016024(Armadillo-type fold)|interpro:IPR024584|mint:Q61037|interpro:IPR000331(Rap/ran-GAP)|interpro:IPR003913(Tuberin)|go:"GO:0001666"(response to hypoxia)|go:"GO:0001843"(neural tube closure)|go:"GO:0001933"(negative regulation of protein phosphorylation)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005764"(lysosome)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005901"(caveola)|go:"GO:0006469"(negative regulation of protein kinase activity)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0007165"(signal transduction)|go:"GO:0007507"(heart development)|go:"GO:0007568"(aging)|go:"GO:0008104"(protein localization)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0010508"(positive regulation of autophagy)|go:"GO:0045792"(negative regulation of cell size)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046323"(glucose import)|go:"GO:0046626"(regulation of insulin receptor signaling pathway)|go:"GO:0046627"(negative regulation of insulin receptor signaling pathway)|go:"GO:0047485"(protein N-terminus binding)|go:"GO:0048009"(insulin-like growth factor receptor signaling pathway)|go:"GO:0048147"(negative regulation of fibroblast proliferation)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0048550"(negative regulation of pinocytosis)|go:"GO:0050680"(negative regulation of epithelial cell proliferation)|go:"GO:0050771"(negative regulation of axonogenesis)|go:"GO:0050918"(positive chemotaxis)|go:"GO:0051056"(regulation of small GTPase mediated signal transduction)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0051879"(Hsp90 protein binding)|go:"GO:0051898"(negative regulation of protein kinase B signaling)|go:"GO:0060999"(positive regulation of dendritic spine development)|go:"GO:0071889"(14-3-3 protein binding)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0045785"(positive regulation of cell adhesion)|go:"GO:1904262"(negative regulation of TORC1 signaling)|go:"GO:1905563"(negative regulation of vascular endothelial cell proliferation)|reactome:R-MMU-1632852|reactome:R-MMU-165181|reactome:R-MMU-198323|reactome:R-MMU-380972|reactome:R-MMU-5628897|reactome:R-MMU-8854214|go:"GO:0099175"(regulation of postsynapse organization)|go:"GO:0010763"(positive regulation of fibroblast migration)|go:"GO:0010976"(positive regulation of neuron projection development)|go:"GO:0014065"(phosphatidylinositol 3-kinase signaling)|go:"GO:0014067"(negative regulation of phosphatidylinositol 3-kinase signaling)|go:"GO:0014069"(postsynaptic density)|go:"GO:0016020"(membrane)|go:"GO:0016239"(positive regulation of macroautophagy)|go:"GO:0016242"(negative regulation of macroautophagy)|go:"GO:0019902"(phosphatase binding)|go:"GO:0030010"(establishment of cell polarity)|go:"GO:0030030"(cell projection organization)|go:"GO:0030100"(regulation of endocytosis)|go:"GO:0030178"(negative regulation of Wnt signaling pathway)|go:"GO:0030425"(dendrite)|go:"GO:0010719"(negative regulation of epithelial to mesenchymal transition)|go:"GO:0031267"(small GTPase binding)|go:"GO:0032007"(negative regulation of TOR signaling)|go:"GO:0032869"(cellular response to insulin stimulus)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033596"(TSC1-TSC2 complex)|go:"GO:0034394"(protein localization to cell surface)|go:"GO:0035176"(social behavior)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0042995"(cell projection)|go:"GO:0043005"(neuron projection)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0043276"(anoikis)|go:"GO:0043407"(negative regulation of MAP kinase activity)|go:"GO:0043491"(protein kinase B signaling)|go:"GO:0043547"(positive regulation of GTPase activity)|go:"GO:0044861"(protein transport into plasma membrane raft)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045121"(membrane raft)|go:"GO:0045184"(establishment of protein localization)|go:"GO:0045202"(synapse)|go:"GO:0030426"(growth cone)|interpro:IPR027107|interpro:IPR035974	go:"GO:0005886"(plasma membrane)|mint:O53319|refseq:NP_217685.1|refseq:WP_003416605.1	-	function:Implicated as a tumor suppressor. May have a function in vesicular transport, but may also play a role in the regulation of cell growth arrest and in the regulation of transcription mediated by steroid receptors. Interaction between TSC1 and TSC2 may facilitate vesicular docking. Specifically stimulates the intrinsic GTPase activity of the ras-related protein RAP1A and RAB5. Suggesting a possible mechanism for its role in regulating cellular growth|comment:mint	-	figure legend:ST5|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2020/07/08	2020/08/14	rogid:Sw17BM+O0FRiPsuF0+h8V/MedTM10090	rogid:Gd1O5B5qTAQflXzn9MR+6fgqvDs83332	rigid:hXkMPbWCVcq5ZqfUuxh0WlSo9j4	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q61037	uniprotkb:O50440	intact:EBI-7924402|uniprotkb:Q61007|uniprotkb:Q61008|uniprotkb:P97724|uniprotkb:P97727|uniprotkb:P97725|intact:MINT-5068541|uniprotkb:Q9WUF6|uniprotkb:P97723	intact:EBI-25767742|uniprotkb:I6XXB2|uniprotkb:L0T7J5	psi-mi:tsc2_mouse(display_long)|uniprotkb:Tuberous sclerosis 2 protein homolog(gene name synonym)|uniprotkb:Tsc2(gene name)|psi-mi:Tsc2(display_short)	psi-mi:chp2_myctu(display_long)|uniprotkb:chp2(gene name)|psi-mi:chp2(display_short)|uniprotkb:LH57_06500(orf name)|uniprotkb:P425_01234(orf name)|uniprotkb:Rv1184c(locus name)|uniprotkb:RVBD_1184c(locus name)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2018)	doi:10.1093/nar/gkx1173|imex:IM-28235|pubmed:29165646	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:83332(myctu)|taxid:83332("Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)")	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0471"(MINT)	intact:EBI-25768652|imex:IM-28235-257	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	interpro:IPR018515|interpro:IPR016024(Armadillo-type fold)|interpro:IPR024584|mint:Q61037|interpro:IPR000331(Rap/ran-GAP)|interpro:IPR003913(Tuberin)|go:"GO:0001666"(response to hypoxia)|go:"GO:0001843"(neural tube closure)|go:"GO:0001933"(negative regulation of protein phosphorylation)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005764"(lysosome)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005901"(caveola)|go:"GO:0006469"(negative regulation of protein kinase activity)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0007165"(signal transduction)|go:"GO:0007507"(heart development)|go:"GO:0007568"(aging)|go:"GO:0008104"(protein localization)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0010508"(positive regulation of autophagy)|go:"GO:0045792"(negative regulation of cell size)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046323"(glucose import)|go:"GO:0046626"(regulation of insulin receptor signaling pathway)|go:"GO:0046627"(negative regulation of insulin receptor signaling pathway)|go:"GO:0047485"(protein N-terminus binding)|go:"GO:0048009"(insulin-like growth factor receptor signaling pathway)|go:"GO:0048147"(negative regulation of fibroblast proliferation)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0048550"(negative regulation of pinocytosis)|go:"GO:0050680"(negative regulation of epithelial cell proliferation)|go:"GO:0050771"(negative regulation of axonogenesis)|go:"GO:0050918"(positive chemotaxis)|go:"GO:0051056"(regulation of small GTPase mediated signal transduction)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0051879"(Hsp90 protein binding)|go:"GO:0051898"(negative regulation of protein kinase B signaling)|go:"GO:0060999"(positive regulation of dendritic spine development)|go:"GO:0071889"(14-3-3 protein binding)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0045785"(positive regulation of cell adhesion)|go:"GO:1904262"(negative regulation of TORC1 signaling)|go:"GO:1905563"(negative regulation of vascular endothelial cell proliferation)|reactome:R-MMU-1632852|reactome:R-MMU-165181|reactome:R-MMU-198323|reactome:R-MMU-380972|reactome:R-MMU-5628897|reactome:R-MMU-8854214|go:"GO:0099175"(regulation of postsynapse organization)|go:"GO:0010763"(positive regulation of fibroblast migration)|go:"GO:0010976"(positive regulation of neuron projection development)|go:"GO:0014065"(phosphatidylinositol 3-kinase signaling)|go:"GO:0014067"(negative regulation of phosphatidylinositol 3-kinase signaling)|go:"GO:0014069"(postsynaptic density)|go:"GO:0016020"(membrane)|go:"GO:0016239"(positive regulation of macroautophagy)|go:"GO:0016242"(negative regulation of macroautophagy)|go:"GO:0019902"(phosphatase binding)|go:"GO:0030010"(establishment of cell polarity)|go:"GO:0030030"(cell projection organization)|go:"GO:0030100"(regulation of endocytosis)|go:"GO:0030178"(negative regulation of Wnt signaling pathway)|go:"GO:0030425"(dendrite)|go:"GO:0010719"(negative regulation of epithelial to mesenchymal transition)|go:"GO:0031267"(small GTPase binding)|go:"GO:0032007"(negative regulation of TOR signaling)|go:"GO:0032869"(cellular response to insulin stimulus)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033596"(TSC1-TSC2 complex)|go:"GO:0034394"(protein localization to cell surface)|go:"GO:0035176"(social behavior)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0042995"(cell projection)|go:"GO:0043005"(neuron projection)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0043276"(anoikis)|go:"GO:0043407"(negative regulation of MAP kinase activity)|go:"GO:0043491"(protein kinase B signaling)|go:"GO:0043547"(positive regulation of GTPase activity)|go:"GO:0044861"(protein transport into plasma membrane raft)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045121"(membrane raft)|go:"GO:0045184"(establishment of protein localization)|go:"GO:0045202"(synapse)|go:"GO:0030426"(growth cone)|interpro:IPR027107|interpro:IPR035974	go:"GO:0005886"(plasma membrane)|go:"GO:0006629"(lipid metabolic process)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016746"(acyltransferase activity)|go:"GO:0005618"(cell wall)|mint:O50440|refseq:NP_215700.1|refseq:WP_003406195.1|interpro:IPR013228(PE-PPE, C-terminal)	-	function:Implicated as a tumor suppressor. May have a function in vesicular transport, but may also play a role in the regulation of cell growth arrest and in the regulation of transcription mediated by steroid receptors. Interaction between TSC1 and TSC2 may facilitate vesicular docking. Specifically stimulates the intrinsic GTPase activity of the ras-related protein RAP1A and RAB5. Suggesting a possible mechanism for its role in regulating cellular growth|comment:mint	-	figure legend:ST5|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2020/07/08	2020/08/14	rogid:Sw17BM+O0FRiPsuF0+h8V/MedTM10090	rogid:IXzYfb7UxFgqBXPZ6NZHLy3hdTc83332	rigid:F+qxUwN5OwLcT3i62AF+p49f+tA	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q61037	uniprotkb:I6YC03	intact:EBI-7924402|uniprotkb:Q61007|uniprotkb:Q61008|uniprotkb:P97724|uniprotkb:P97727|uniprotkb:P97725|intact:MINT-5068541|uniprotkb:Q9WUF6|uniprotkb:P97723	intact:EBI-25768074	psi-mi:tsc2_mouse(display_long)|uniprotkb:Tuberous sclerosis 2 protein homolog(gene name synonym)|uniprotkb:Tsc2(gene name)|psi-mi:Tsc2(display_short)	psi-mi:ephb_myctu(display_long)|uniprotkb:ephB(gene name)|psi-mi:ephB(display_short)|uniprotkb:Epoxide hydrolase EphB(gene name synonym)|uniprotkb:LH57_10545(orf name)|uniprotkb:Rv1938(locus name)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2018)	doi:10.1093/nar/gkx1173|imex:IM-28235|pubmed:29165646	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:83332(myctu)|taxid:83332("Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)")	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0471"(MINT)	intact:EBI-25768646|imex:IM-28235-255	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	interpro:IPR018515|interpro:IPR016024(Armadillo-type fold)|interpro:IPR024584|mint:Q61037|interpro:IPR000331(Rap/ran-GAP)|interpro:IPR003913(Tuberin)|go:"GO:0001666"(response to hypoxia)|go:"GO:0001843"(neural tube closure)|go:"GO:0001933"(negative regulation of protein phosphorylation)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005764"(lysosome)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005901"(caveola)|go:"GO:0006469"(negative regulation of protein kinase activity)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0007165"(signal transduction)|go:"GO:0007507"(heart development)|go:"GO:0007568"(aging)|go:"GO:0008104"(protein localization)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0010508"(positive regulation of autophagy)|go:"GO:0045792"(negative regulation of cell size)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046323"(glucose import)|go:"GO:0046626"(regulation of insulin receptor signaling pathway)|go:"GO:0046627"(negative regulation of insulin receptor signaling pathway)|go:"GO:0047485"(protein N-terminus binding)|go:"GO:0048009"(insulin-like growth factor receptor signaling pathway)|go:"GO:0048147"(negative regulation of fibroblast proliferation)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0048550"(negative regulation of pinocytosis)|go:"GO:0050680"(negative regulation of epithelial cell proliferation)|go:"GO:0050771"(negative regulation of axonogenesis)|go:"GO:0050918"(positive chemotaxis)|go:"GO:0051056"(regulation of small GTPase mediated signal transduction)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0051879"(Hsp90 protein binding)|go:"GO:0051898"(negative regulation of protein kinase B signaling)|go:"GO:0060999"(positive regulation of dendritic spine development)|go:"GO:0071889"(14-3-3 protein binding)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0045785"(positive regulation of cell adhesion)|go:"GO:1904262"(negative regulation of TORC1 signaling)|go:"GO:1905563"(negative regulation of vascular endothelial cell proliferation)|reactome:R-MMU-1632852|reactome:R-MMU-165181|reactome:R-MMU-198323|reactome:R-MMU-380972|reactome:R-MMU-5628897|reactome:R-MMU-8854214|go:"GO:0099175"(regulation of postsynapse organization)|go:"GO:0010763"(positive regulation of fibroblast migration)|go:"GO:0010976"(positive regulation of neuron projection development)|go:"GO:0014065"(phosphatidylinositol 3-kinase signaling)|go:"GO:0014067"(negative regulation of phosphatidylinositol 3-kinase signaling)|go:"GO:0014069"(postsynaptic density)|go:"GO:0016020"(membrane)|go:"GO:0016239"(positive regulation of macroautophagy)|go:"GO:0016242"(negative regulation of macroautophagy)|go:"GO:0019902"(phosphatase binding)|go:"GO:0030010"(establishment of cell polarity)|go:"GO:0030030"(cell projection organization)|go:"GO:0030100"(regulation of endocytosis)|go:"GO:0030178"(negative regulation of Wnt signaling pathway)|go:"GO:0030425"(dendrite)|go:"GO:0010719"(negative regulation of epithelial to mesenchymal transition)|go:"GO:0031267"(small GTPase binding)|go:"GO:0032007"(negative regulation of TOR signaling)|go:"GO:0032869"(cellular response to insulin stimulus)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033596"(TSC1-TSC2 complex)|go:"GO:0034394"(protein localization to cell surface)|go:"GO:0035176"(social behavior)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0042995"(cell projection)|go:"GO:0043005"(neuron projection)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0043276"(anoikis)|go:"GO:0043407"(negative regulation of MAP kinase activity)|go:"GO:0043491"(protein kinase B signaling)|go:"GO:0043547"(positive regulation of GTPase activity)|go:"GO:0044861"(protein transport into plasma membrane raft)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045121"(membrane raft)|go:"GO:0045184"(establishment of protein localization)|go:"GO:0045202"(synapse)|go:"GO:0030426"(growth cone)|interpro:IPR027107|interpro:IPR035974	go:"GO:0009636"(response to toxic substance)|go:"GO:0016787"(hydrolase activity)|go:"GO:0018742"(epoxide hydrolase B activity)|go:"GO:0042803"(protein homodimerization activity)|mint:I6YC03|refseq:NP_216454.1|refseq:WP_003899091.1|interpro:IPR029058|interpro:IPR000073(Alpha/beta hydrolase fold-1)|interpro:IPR000639(Epoxide hydrolase-like)	-	function:Implicated as a tumor suppressor. May have a function in vesicular transport, but may also play a role in the regulation of cell growth arrest and in the regulation of transcription mediated by steroid receptors. Interaction between TSC1 and TSC2 may facilitate vesicular docking. Specifically stimulates the intrinsic GTPase activity of the ras-related protein RAP1A and RAB5. Suggesting a possible mechanism for its role in regulating cellular growth|comment:mint	-	figure legend:ST5|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2020/07/08	2020/08/14	rogid:Sw17BM+O0FRiPsuF0+h8V/MedTM10090	rogid:sRxqN+k+jfx7zSE+ctNP+i+id0I83332	rigid:9zVZZTrP+KP9keNDIVkIoDMcSGc	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P9WHT9	uniprotkb:Q61037	intact:EBI-7947958|uniprotkb:O33245|intact:MINT-7985947|uniprotkb:Q7D7I2|uniprotkb:L0T8V8	intact:EBI-7924402|uniprotkb:Q61007|uniprotkb:Q61008|uniprotkb:P97724|uniprotkb:P97727|uniprotkb:P97725|intact:MINT-5068541|uniprotkb:Q9WUF6|uniprotkb:P97723	psi-mi:psb_myctu(display_long)|uniprotkb:Proteasome core protein PrcB(gene name synonym)|uniprotkb:Rv2110c(locus name)|uniprotkb:prcB(gene name)|psi-mi:prcB(display_short)|uniprotkb:20S proteasome beta subunit(gene name synonym)	psi-mi:tsc2_mouse(display_long)|uniprotkb:Tuberous sclerosis 2 protein homolog(gene name synonym)|uniprotkb:Tsc2(gene name)|psi-mi:Tsc2(display_short)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2018)	doi:10.1093/nar/gkx1173|imex:IM-28235|pubmed:29165646	taxid:83332(myctu)|taxid:83332("Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)")	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0471"(MINT)	intact:EBI-25768640|imex:IM-28235-335	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	interpro:IPR029055|refseq:WP_003411023.1|interpro:IPR001353(20S proteasome, A and B subunits)|refseq:NP_216626.1|interpro:IPR023333|interpro:IPR022483|mint:P9WHT9|go:"GO:0004298"(threonine-type endopeptidase activity)|go:"GO:0005576"(extracellular region)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0010498"(proteasomal protein catabolic process)|go:"GO:0019773"(proteasome core complex, alpha-subunit complex)|go:"GO:0019774"(proteasome core complex, beta-subunit complex)|go:"GO:0019941"(modification-dependent protein catabolic process)|go:"GO:0030682"(mitigation of host defenses by symbiont)|go:"GO:0035375"(zymogen binding)|go:"GO:0051603"(proteolysis involved in cellular protein catabolic process)|rcsb pdb:2FHG|rcsb pdb:2FHH|rcsb pdb:2JAY|rcsb pdb:3H6F|rcsb pdb:3H6I|rcsb pdb:3HF9|rcsb pdb:3HFA|rcsb pdb:3KRD|rcsb pdb:3MFE|rcsb pdb:3MI0|rcsb pdb:3MKA|rcsb pdb:5LZP|rcsb pdb:5THO|rcsb pdb:5TRG|rcsb pdb:5TRR|rcsb pdb:5TRS|rcsb pdb:5TRY|rcsb pdb:5TS0|rcsb pdb:6BGL|rcsb pdb:6BGO|rcsb pdb:6OCW|rcsb pdb:6OCZ|rcsb pdb:6ODE	interpro:IPR018515|interpro:IPR016024(Armadillo-type fold)|interpro:IPR024584|mint:Q61037|interpro:IPR000331(Rap/ran-GAP)|interpro:IPR003913(Tuberin)|go:"GO:0001666"(response to hypoxia)|go:"GO:0001843"(neural tube closure)|go:"GO:0001933"(negative regulation of protein phosphorylation)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005764"(lysosome)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005901"(caveola)|go:"GO:0006469"(negative regulation of protein kinase activity)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0007165"(signal transduction)|go:"GO:0007507"(heart development)|go:"GO:0007568"(aging)|go:"GO:0008104"(protein localization)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0010508"(positive regulation of autophagy)|go:"GO:0045792"(negative regulation of cell size)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046323"(glucose import)|go:"GO:0046626"(regulation of insulin receptor signaling pathway)|go:"GO:0046627"(negative regulation of insulin receptor signaling pathway)|go:"GO:0047485"(protein N-terminus binding)|go:"GO:0048009"(insulin-like growth factor receptor signaling pathway)|go:"GO:0048147"(negative regulation of fibroblast proliferation)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0048550"(negative regulation of pinocytosis)|go:"GO:0050680"(negative regulation of epithelial cell proliferation)|go:"GO:0050771"(negative regulation of axonogenesis)|go:"GO:0050918"(positive chemotaxis)|go:"GO:0051056"(regulation of small GTPase mediated signal transduction)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0051879"(Hsp90 protein binding)|go:"GO:0051898"(negative regulation of protein kinase B signaling)|go:"GO:0060999"(positive regulation of dendritic spine development)|go:"GO:0071889"(14-3-3 protein binding)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0045785"(positive regulation of cell adhesion)|go:"GO:1904262"(negative regulation of TORC1 signaling)|go:"GO:1905563"(negative regulation of vascular endothelial cell proliferation)|reactome:R-MMU-1632852|reactome:R-MMU-165181|reactome:R-MMU-198323|reactome:R-MMU-380972|reactome:R-MMU-5628897|reactome:R-MMU-8854214|go:"GO:0099175"(regulation of postsynapse organization)|go:"GO:0010763"(positive regulation of fibroblast migration)|go:"GO:0010976"(positive regulation of neuron projection development)|go:"GO:0014065"(phosphatidylinositol 3-kinase signaling)|go:"GO:0014067"(negative regulation of phosphatidylinositol 3-kinase signaling)|go:"GO:0014069"(postsynaptic density)|go:"GO:0016020"(membrane)|go:"GO:0016239"(positive regulation of macroautophagy)|go:"GO:0016242"(negative regulation of macroautophagy)|go:"GO:0019902"(phosphatase binding)|go:"GO:0030010"(establishment of cell polarity)|go:"GO:0030030"(cell projection organization)|go:"GO:0030100"(regulation of endocytosis)|go:"GO:0030178"(negative regulation of Wnt signaling pathway)|go:"GO:0030425"(dendrite)|go:"GO:0010719"(negative regulation of epithelial to mesenchymal transition)|go:"GO:0031267"(small GTPase binding)|go:"GO:0032007"(negative regulation of TOR signaling)|go:"GO:0032869"(cellular response to insulin stimulus)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033596"(TSC1-TSC2 complex)|go:"GO:0034394"(protein localization to cell surface)|go:"GO:0035176"(social behavior)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0042995"(cell projection)|go:"GO:0043005"(neuron projection)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0043276"(anoikis)|go:"GO:0043407"(negative regulation of MAP kinase activity)|go:"GO:0043491"(protein kinase B signaling)|go:"GO:0043547"(positive regulation of GTPase activity)|go:"GO:0044861"(protein transport into plasma membrane raft)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045121"(membrane raft)|go:"GO:0045184"(establishment of protein localization)|go:"GO:0045202"(synapse)|go:"GO:0030426"(growth cone)|interpro:IPR027107|interpro:IPR035974	-	crc64:3FC3FCD81231E129|comment:mint	function:Implicated as a tumor suppressor. May have a function in vesicular transport, but may also play a role in the regulation of cell growth arrest and in the regulation of transcription mediated by steroid receptors. Interaction between TSC1 and TSC2 may facilitate vesicular docking. Specifically stimulates the intrinsic GTPase activity of the ras-related protein RAP1A and RAB5. Suggesting a possible mechanism for its role in regulating cellular growth|comment:mint	figure legend:ST5|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2020/07/08	2020/08/14	rogid:hQ8Eci/BIL/quaWNhklTdFRPHDI83332	rogid:Sw17BM+O0FRiPsuF0+h8V/MedTM10090	rigid:/UjIuowg0EcXt83UrtI8eSiI92k	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q61037	uniprotkb:I6Y946	intact:EBI-7924402|uniprotkb:Q61007|uniprotkb:Q61008|uniprotkb:P97724|uniprotkb:P97727|uniprotkb:P97725|intact:MINT-5068541|uniprotkb:Q9WUF6|uniprotkb:P97723	intact:EBI-25767727	psi-mi:tsc2_mouse(display_long)|uniprotkb:Tuberous sclerosis 2 protein homolog(gene name synonym)|uniprotkb:Tsc2(gene name)|psi-mi:Tsc2(display_short)	psi-mi:i6y946_myctu(display_long)|uniprotkb:Rv0925c(locus name)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2018)	doi:10.1093/nar/gkx1173|imex:IM-28235|pubmed:29165646	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:83332(myctu)|taxid:83332("Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)")	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0471"(MINT)	intact:EBI-25768634|imex:IM-28235-333	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	interpro:IPR018515|interpro:IPR016024(Armadillo-type fold)|interpro:IPR024584|mint:Q61037|interpro:IPR000331(Rap/ran-GAP)|interpro:IPR003913(Tuberin)|go:"GO:0001666"(response to hypoxia)|go:"GO:0001843"(neural tube closure)|go:"GO:0001933"(negative regulation of protein phosphorylation)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005764"(lysosome)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005901"(caveola)|go:"GO:0006469"(negative regulation of protein kinase activity)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0007165"(signal transduction)|go:"GO:0007507"(heart development)|go:"GO:0007568"(aging)|go:"GO:0008104"(protein localization)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0010508"(positive regulation of autophagy)|go:"GO:0045792"(negative regulation of cell size)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046323"(glucose import)|go:"GO:0046626"(regulation of insulin receptor signaling pathway)|go:"GO:0046627"(negative regulation of insulin receptor signaling pathway)|go:"GO:0047485"(protein N-terminus binding)|go:"GO:0048009"(insulin-like growth factor receptor signaling pathway)|go:"GO:0048147"(negative regulation of fibroblast proliferation)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0048550"(negative regulation of pinocytosis)|go:"GO:0050680"(negative regulation of epithelial cell proliferation)|go:"GO:0050771"(negative regulation of axonogenesis)|go:"GO:0050918"(positive chemotaxis)|go:"GO:0051056"(regulation of small GTPase mediated signal transduction)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0051879"(Hsp90 protein binding)|go:"GO:0051898"(negative regulation of protein kinase B signaling)|go:"GO:0060999"(positive regulation of dendritic spine development)|go:"GO:0071889"(14-3-3 protein binding)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0045785"(positive regulation of cell adhesion)|go:"GO:1904262"(negative regulation of TORC1 signaling)|go:"GO:1905563"(negative regulation of vascular endothelial cell proliferation)|reactome:R-MMU-1632852|reactome:R-MMU-165181|reactome:R-MMU-198323|reactome:R-MMU-380972|reactome:R-MMU-5628897|reactome:R-MMU-8854214|go:"GO:0099175"(regulation of postsynapse organization)|go:"GO:0010763"(positive regulation of fibroblast migration)|go:"GO:0010976"(positive regulation of neuron projection development)|go:"GO:0014065"(phosphatidylinositol 3-kinase signaling)|go:"GO:0014067"(negative regulation of phosphatidylinositol 3-kinase signaling)|go:"GO:0014069"(postsynaptic density)|go:"GO:0016020"(membrane)|go:"GO:0016239"(positive regulation of macroautophagy)|go:"GO:0016242"(negative regulation of macroautophagy)|go:"GO:0019902"(phosphatase binding)|go:"GO:0030010"(establishment of cell polarity)|go:"GO:0030030"(cell projection organization)|go:"GO:0030100"(regulation of endocytosis)|go:"GO:0030178"(negative regulation of Wnt signaling pathway)|go:"GO:0030425"(dendrite)|go:"GO:0010719"(negative regulation of epithelial to mesenchymal transition)|go:"GO:0031267"(small GTPase binding)|go:"GO:0032007"(negative regulation of TOR signaling)|go:"GO:0032869"(cellular response to insulin stimulus)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033596"(TSC1-TSC2 complex)|go:"GO:0034394"(protein localization to cell surface)|go:"GO:0035176"(social behavior)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0042995"(cell projection)|go:"GO:0043005"(neuron projection)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0043276"(anoikis)|go:"GO:0043407"(negative regulation of MAP kinase activity)|go:"GO:0043491"(protein kinase B signaling)|go:"GO:0043547"(positive regulation of GTPase activity)|go:"GO:0044861"(protein transport into plasma membrane raft)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045121"(membrane raft)|go:"GO:0045184"(establishment of protein localization)|go:"GO:0045202"(synapse)|go:"GO:0030426"(growth cone)|interpro:IPR027107|interpro:IPR035974	go:"GO:0016491"(oxidoreductase activity)|mint:I6Y946|refseq:NP_215440.1|refseq:WP_003404764.1|interpro:IPR029039|interpro:IPR005025(NADPH-dependent FMN reductase)	-	function:Implicated as a tumor suppressor. May have a function in vesicular transport, but may also play a role in the regulation of cell growth arrest and in the regulation of transcription mediated by steroid receptors. Interaction between TSC1 and TSC2 may facilitate vesicular docking. Specifically stimulates the intrinsic GTPase activity of the ras-related protein RAP1A and RAB5. Suggesting a possible mechanism for its role in regulating cellular growth|comment:mint	-	figure legend:ST5|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2020/07/08	2020/08/14	rogid:Sw17BM+O0FRiPsuF0+h8V/MedTM10090	rogid:JOW06LtizimdrjJdMmMnM9ru8n083332	rigid:gQQAtebScTMTFY9/j2BfTMTH4uQ	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q61037	uniprotkb:O07422	intact:EBI-7924402|uniprotkb:Q61007|uniprotkb:Q61008|uniprotkb:P97724|uniprotkb:P97727|uniprotkb:P97725|intact:MINT-5068541|uniprotkb:Q9WUF6|uniprotkb:P97723	intact:EBI-25767563|uniprotkb:F2GLX6|uniprotkb:I6Y302|uniprotkb:Q7DAB9	psi-mi:tsc2_mouse(display_long)|uniprotkb:Tuberous sclerosis 2 protein homolog(gene name synonym)|uniprotkb:Tsc2(gene name)|psi-mi:Tsc2(display_short)	psi-mi:o07422_myctu(display_long)|uniprotkb:Rv0178(locus name)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2018)	doi:10.1093/nar/gkx1173|imex:IM-28235|pubmed:29165646	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:83332(myctu)|taxid:83332("Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)")	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0471"(MINT)	intact:EBI-25768628|imex:IM-28235-253	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	interpro:IPR018515|interpro:IPR016024(Armadillo-type fold)|interpro:IPR024584|mint:Q61037|interpro:IPR000331(Rap/ran-GAP)|interpro:IPR003913(Tuberin)|go:"GO:0001666"(response to hypoxia)|go:"GO:0001843"(neural tube closure)|go:"GO:0001933"(negative regulation of protein phosphorylation)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005764"(lysosome)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005901"(caveola)|go:"GO:0006469"(negative regulation of protein kinase activity)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0007165"(signal transduction)|go:"GO:0007507"(heart development)|go:"GO:0007568"(aging)|go:"GO:0008104"(protein localization)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0010508"(positive regulation of autophagy)|go:"GO:0045792"(negative regulation of cell size)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046323"(glucose import)|go:"GO:0046626"(regulation of insulin receptor signaling pathway)|go:"GO:0046627"(negative regulation of insulin receptor signaling pathway)|go:"GO:0047485"(protein N-terminus binding)|go:"GO:0048009"(insulin-like growth factor receptor signaling pathway)|go:"GO:0048147"(negative regulation of fibroblast proliferation)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0048550"(negative regulation of pinocytosis)|go:"GO:0050680"(negative regulation of epithelial cell proliferation)|go:"GO:0050771"(negative regulation of axonogenesis)|go:"GO:0050918"(positive chemotaxis)|go:"GO:0051056"(regulation of small GTPase mediated signal transduction)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0051879"(Hsp90 protein binding)|go:"GO:0051898"(negative regulation of protein kinase B signaling)|go:"GO:0060999"(positive regulation of dendritic spine development)|go:"GO:0071889"(14-3-3 protein binding)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0045785"(positive regulation of cell adhesion)|go:"GO:1904262"(negative regulation of TORC1 signaling)|go:"GO:1905563"(negative regulation of vascular endothelial cell proliferation)|reactome:R-MMU-1632852|reactome:R-MMU-165181|reactome:R-MMU-198323|reactome:R-MMU-380972|reactome:R-MMU-5628897|reactome:R-MMU-8854214|go:"GO:0099175"(regulation of postsynapse organization)|go:"GO:0010763"(positive regulation of fibroblast migration)|go:"GO:0010976"(positive regulation of neuron projection development)|go:"GO:0014065"(phosphatidylinositol 3-kinase signaling)|go:"GO:0014067"(negative regulation of phosphatidylinositol 3-kinase signaling)|go:"GO:0014069"(postsynaptic density)|go:"GO:0016020"(membrane)|go:"GO:0016239"(positive regulation of macroautophagy)|go:"GO:0016242"(negative regulation of macroautophagy)|go:"GO:0019902"(phosphatase binding)|go:"GO:0030010"(establishment of cell polarity)|go:"GO:0030030"(cell projection organization)|go:"GO:0030100"(regulation of endocytosis)|go:"GO:0030178"(negative regulation of Wnt signaling pathway)|go:"GO:0030425"(dendrite)|go:"GO:0010719"(negative regulation of epithelial to mesenchymal transition)|go:"GO:0031267"(small GTPase binding)|go:"GO:0032007"(negative regulation of TOR signaling)|go:"GO:0032869"(cellular response to insulin stimulus)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033596"(TSC1-TSC2 complex)|go:"GO:0034394"(protein localization to cell surface)|go:"GO:0035176"(social behavior)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0042995"(cell projection)|go:"GO:0043005"(neuron projection)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0043276"(anoikis)|go:"GO:0043407"(negative regulation of MAP kinase activity)|go:"GO:0043491"(protein kinase B signaling)|go:"GO:0043547"(positive regulation of GTPase activity)|go:"GO:0044861"(protein transport into plasma membrane raft)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045121"(membrane raft)|go:"GO:0045184"(establishment of protein localization)|go:"GO:0045202"(synapse)|go:"GO:0030426"(growth cone)|interpro:IPR027107|interpro:IPR035974	go:"GO:0005576"(extracellular region)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0051701"(biological process involved in interaction with host)|mint:O07422|refseq:NP_214692.1|refseq:WP_003899844.1	-	function:Implicated as a tumor suppressor. May have a function in vesicular transport, but may also play a role in the regulation of cell growth arrest and in the regulation of transcription mediated by steroid receptors. Interaction between TSC1 and TSC2 may facilitate vesicular docking. Specifically stimulates the intrinsic GTPase activity of the ras-related protein RAP1A and RAB5. Suggesting a possible mechanism for its role in regulating cellular growth|comment:mint	-	figure legend:ST5|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2020/07/08	2020/08/14	rogid:Sw17BM+O0FRiPsuF0+h8V/MedTM10090	rogid:lGOg72Osvz8819m674JzGUcHEj483332	rigid:S4ve4Jdq9Ru1ghxcvD7MXffxGz0	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q61037	uniprotkb:P9WP17	intact:EBI-7924402|uniprotkb:Q61007|uniprotkb:Q61008|uniprotkb:P97724|uniprotkb:P97727|uniprotkb:P97725|intact:MINT-5068541|uniprotkb:Q9WUF6|uniprotkb:P97723	intact:EBI-25767691|uniprotkb:L0T3B0|uniprotkb:O07247	psi-mi:tsc2_mouse(display_long)|uniprotkb:Tuberous sclerosis 2 protein homolog(gene name synonym)|uniprotkb:Tsc2(gene name)|psi-mi:Tsc2(display_short)	psi-mi:dcdb_myctu(display_long)|uniprotkb:dcd(gene name)|psi-mi:dcd(display_short)|uniprotkb:"Bifunctional dCTP deaminase:dUTPase"(gene name synonym)|uniprotkb:DCD-DUT(gene name synonym)|uniprotkb:MTCY63.26(orf name)|uniprotkb:Rv0321(locus name)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2018)	doi:10.1093/nar/gkx1173|imex:IM-28235|pubmed:29165646	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:83332(myctu)|taxid:83332("Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)")	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0471"(MINT)	intact:EBI-25768622|imex:IM-28235-251	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	interpro:IPR018515|interpro:IPR016024(Armadillo-type fold)|interpro:IPR024584|mint:Q61037|interpro:IPR000331(Rap/ran-GAP)|interpro:IPR003913(Tuberin)|go:"GO:0001666"(response to hypoxia)|go:"GO:0001843"(neural tube closure)|go:"GO:0001933"(negative regulation of protein phosphorylation)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005764"(lysosome)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005901"(caveola)|go:"GO:0006469"(negative regulation of protein kinase activity)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0007165"(signal transduction)|go:"GO:0007507"(heart development)|go:"GO:0007568"(aging)|go:"GO:0008104"(protein localization)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0010508"(positive regulation of autophagy)|go:"GO:0045792"(negative regulation of cell size)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046323"(glucose import)|go:"GO:0046626"(regulation of insulin receptor signaling pathway)|go:"GO:0046627"(negative regulation of insulin receptor signaling pathway)|go:"GO:0047485"(protein N-terminus binding)|go:"GO:0048009"(insulin-like growth factor receptor signaling pathway)|go:"GO:0048147"(negative regulation of fibroblast proliferation)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0048550"(negative regulation of pinocytosis)|go:"GO:0050680"(negative regulation of epithelial cell proliferation)|go:"GO:0050771"(negative regulation of axonogenesis)|go:"GO:0050918"(positive chemotaxis)|go:"GO:0051056"(regulation of small GTPase mediated signal transduction)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0051879"(Hsp90 protein binding)|go:"GO:0051898"(negative regulation of protein kinase B signaling)|go:"GO:0060999"(positive regulation of dendritic spine development)|go:"GO:0071889"(14-3-3 protein binding)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0045785"(positive regulation of cell adhesion)|go:"GO:1904262"(negative regulation of TORC1 signaling)|go:"GO:1905563"(negative regulation of vascular endothelial cell proliferation)|reactome:R-MMU-1632852|reactome:R-MMU-165181|reactome:R-MMU-198323|reactome:R-MMU-380972|reactome:R-MMU-5628897|reactome:R-MMU-8854214|go:"GO:0099175"(regulation of postsynapse organization)|go:"GO:0010763"(positive regulation of fibroblast migration)|go:"GO:0010976"(positive regulation of neuron projection development)|go:"GO:0014065"(phosphatidylinositol 3-kinase signaling)|go:"GO:0014067"(negative regulation of phosphatidylinositol 3-kinase signaling)|go:"GO:0014069"(postsynaptic density)|go:"GO:0016020"(membrane)|go:"GO:0016239"(positive regulation of macroautophagy)|go:"GO:0016242"(negative regulation of macroautophagy)|go:"GO:0019902"(phosphatase binding)|go:"GO:0030010"(establishment of cell polarity)|go:"GO:0030030"(cell projection organization)|go:"GO:0030100"(regulation of endocytosis)|go:"GO:0030178"(negative regulation of Wnt signaling pathway)|go:"GO:0030425"(dendrite)|go:"GO:0010719"(negative regulation of epithelial to mesenchymal transition)|go:"GO:0031267"(small GTPase binding)|go:"GO:0032007"(negative regulation of TOR signaling)|go:"GO:0032869"(cellular response to insulin stimulus)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033596"(TSC1-TSC2 complex)|go:"GO:0034394"(protein localization to cell surface)|go:"GO:0035176"(social behavior)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0042995"(cell projection)|go:"GO:0043005"(neuron projection)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0043276"(anoikis)|go:"GO:0043407"(negative regulation of MAP kinase activity)|go:"GO:0043491"(protein kinase B signaling)|go:"GO:0043547"(positive regulation of GTPase activity)|go:"GO:0044861"(protein transport into plasma membrane raft)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045121"(membrane raft)|go:"GO:0045184"(establishment of protein localization)|go:"GO:0045202"(synapse)|go:"GO:0030426"(growth cone)|interpro:IPR027107|interpro:IPR035974	go:"GO:0000166"(nucleotide binding)|go:"GO:0004170"(dUTP diphosphatase activity)|go:"GO:0006226"(dUMP biosynthetic process)|go:"GO:0006229"(dUTP biosynthetic process)|go:"GO:0008829"(dCTP deaminase activity)|go:"GO:0015949"(nucleobase-containing small molecule interconversion)|go:"GO:0033973"("dCTP deaminase (dUMP-forming) activity")|rcsb pdb:2QLP|rcsb pdb:2QXX|rcsb pdb:4A6A|mint:P9WP17|refseq:NP_214835.1|refseq:WP_003898399.1|interpro:IPR011962(Deoxycytidine triphosphate deaminase)|interpro:IPR029054|interpro:IPR036157|interpro:IPR033704	-	function:Implicated as a tumor suppressor. May have a function in vesicular transport, but may also play a role in the regulation of cell growth arrest and in the regulation of transcription mediated by steroid receptors. Interaction between TSC1 and TSC2 may facilitate vesicular docking. Specifically stimulates the intrinsic GTPase activity of the ras-related protein RAP1A and RAB5. Suggesting a possible mechanism for its role in regulating cellular growth|comment:mint	-	figure legend:ST5|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2020/07/08	2020/08/14	rogid:Sw17BM+O0FRiPsuF0+h8V/MedTM10090	rogid:7Llq0DbdMabIKeH06jyXlfJfD3083332	rigid:HNE5djIp6YbuxmOSDW4IqT9TnI8	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q61037	uniprotkb:P9WJB9	intact:EBI-7924402|uniprotkb:Q61007|uniprotkb:Q61008|uniprotkb:P97724|uniprotkb:P97727|uniprotkb:P97725|intact:MINT-5068541|uniprotkb:Q9WUF6|uniprotkb:P97723	intact:EBI-25767670|uniprotkb:L0TE21|uniprotkb:O69744|uniprotkb:Q7D4P0	psi-mi:tsc2_mouse(display_long)|uniprotkb:Tuberous sclerosis 2 protein homolog(gene name synonym)|uniprotkb:Tsc2(gene name)|psi-mi:Tsc2(display_short)	psi-mi:espl_myctu(display_long)|uniprotkb:espL(gene name)|psi-mi:espL(display_short)|uniprotkb:Rv3880c(locus name)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2018)	doi:10.1093/nar/gkx1173|imex:IM-28235|pubmed:29165646	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:83332(myctu)|taxid:83332("Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)")	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0471"(MINT)	intact:EBI-25768616|imex:IM-28235-209	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	interpro:IPR018515|interpro:IPR016024(Armadillo-type fold)|interpro:IPR024584|mint:Q61037|interpro:IPR000331(Rap/ran-GAP)|interpro:IPR003913(Tuberin)|go:"GO:0001666"(response to hypoxia)|go:"GO:0001843"(neural tube closure)|go:"GO:0001933"(negative regulation of protein phosphorylation)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005764"(lysosome)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005901"(caveola)|go:"GO:0006469"(negative regulation of protein kinase activity)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0007165"(signal transduction)|go:"GO:0007507"(heart development)|go:"GO:0007568"(aging)|go:"GO:0008104"(protein localization)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0010508"(positive regulation of autophagy)|go:"GO:0045792"(negative regulation of cell size)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046323"(glucose import)|go:"GO:0046626"(regulation of insulin receptor signaling pathway)|go:"GO:0046627"(negative regulation of insulin receptor signaling pathway)|go:"GO:0047485"(protein N-terminus binding)|go:"GO:0048009"(insulin-like growth factor receptor signaling pathway)|go:"GO:0048147"(negative regulation of fibroblast proliferation)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0048550"(negative regulation of pinocytosis)|go:"GO:0050680"(negative regulation of epithelial cell proliferation)|go:"GO:0050771"(negative regulation of axonogenesis)|go:"GO:0050918"(positive chemotaxis)|go:"GO:0051056"(regulation of small GTPase mediated signal transduction)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0051879"(Hsp90 protein binding)|go:"GO:0051898"(negative regulation of protein kinase B signaling)|go:"GO:0060999"(positive regulation of dendritic spine development)|go:"GO:0071889"(14-3-3 protein binding)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0045785"(positive regulation of cell adhesion)|go:"GO:1904262"(negative regulation of TORC1 signaling)|go:"GO:1905563"(negative regulation of vascular endothelial cell proliferation)|reactome:R-MMU-1632852|reactome:R-MMU-165181|reactome:R-MMU-198323|reactome:R-MMU-380972|reactome:R-MMU-5628897|reactome:R-MMU-8854214|go:"GO:0099175"(regulation of postsynapse organization)|go:"GO:0010763"(positive regulation of fibroblast migration)|go:"GO:0010976"(positive regulation of neuron projection development)|go:"GO:0014065"(phosphatidylinositol 3-kinase signaling)|go:"GO:0014067"(negative regulation of phosphatidylinositol 3-kinase signaling)|go:"GO:0014069"(postsynaptic density)|go:"GO:0016020"(membrane)|go:"GO:0016239"(positive regulation of macroautophagy)|go:"GO:0016242"(negative regulation of macroautophagy)|go:"GO:0019902"(phosphatase binding)|go:"GO:0030010"(establishment of cell polarity)|go:"GO:0030030"(cell projection organization)|go:"GO:0030100"(regulation of endocytosis)|go:"GO:0030178"(negative regulation of Wnt signaling pathway)|go:"GO:0030425"(dendrite)|go:"GO:0010719"(negative regulation of epithelial to mesenchymal transition)|go:"GO:0031267"(small GTPase binding)|go:"GO:0032007"(negative regulation of TOR signaling)|go:"GO:0032869"(cellular response to insulin stimulus)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033596"(TSC1-TSC2 complex)|go:"GO:0034394"(protein localization to cell surface)|go:"GO:0035176"(social behavior)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0042995"(cell projection)|go:"GO:0043005"(neuron projection)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0043276"(anoikis)|go:"GO:0043407"(negative regulation of MAP kinase activity)|go:"GO:0043491"(protein kinase B signaling)|go:"GO:0043547"(positive regulation of GTPase activity)|go:"GO:0044861"(protein transport into plasma membrane raft)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045121"(membrane raft)|go:"GO:0045184"(establishment of protein localization)|go:"GO:0045202"(synapse)|go:"GO:0030426"(growth cone)|interpro:IPR027107|interpro:IPR035974	go:"GO:0003677"(DNA binding)|go:"GO:0005618"(cell wall)|go:"GO:0005886"(plasma membrane)|go:"GO:0052170"(suppression by symbiont of host innate immune response)|mint:P9WJB9|refseq:NP_218397.1|refseq:WP_003399988.1|interpro:IPR036894|interpro:IPR004401(Conserved hypothetical protein CHP00103)	-	function:Implicated as a tumor suppressor. May have a function in vesicular transport, but may also play a role in the regulation of cell growth arrest and in the regulation of transcription mediated by steroid receptors. Interaction between TSC1 and TSC2 may facilitate vesicular docking. Specifically stimulates the intrinsic GTPase activity of the ras-related protein RAP1A and RAB5. Suggesting a possible mechanism for its role in regulating cellular growth|comment:mint	-	figure legend:ST5|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2020/07/08	2020/08/14	rogid:Sw17BM+O0FRiPsuF0+h8V/MedTM10090	rogid:BspTx2RZuhJaQ319NBDIyOreqfE83332	rigid:ktgY9P/9E5JjKA9bUX/XOtGT6LU	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q61037	uniprotkb:P9WNI7	intact:EBI-7924402|uniprotkb:Q61007|uniprotkb:Q61008|uniprotkb:P97724|uniprotkb:P97727|uniprotkb:P97725|intact:MINT-5068541|uniprotkb:Q9WUF6|uniprotkb:P97723	intact:EBI-9027314|uniprotkb:P95242|uniprotkb:L0T9C9	psi-mi:tsc2_mouse(display_long)|uniprotkb:Tuberous sclerosis 2 protein homolog(gene name synonym)|uniprotkb:Tsc2(gene name)|psi-mi:Tsc2(display_short)	psi-mi:esxo_myctu(display_long)|uniprotkb:esxO(gene name)|psi-mi:esxO(display_short)|uniprotkb:MTCY98.15c(orf name)|uniprotkb:Rv2346c(locus name)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2018)	doi:10.1093/nar/gkx1173|imex:IM-28235|pubmed:29165646	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:83332(myctu)|taxid:83332("Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)")	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0471"(MINT)	intact:EBI-25768610|imex:IM-28235-249	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	interpro:IPR018515|interpro:IPR016024(Armadillo-type fold)|interpro:IPR024584|mint:Q61037|interpro:IPR000331(Rap/ran-GAP)|interpro:IPR003913(Tuberin)|go:"GO:0001666"(response to hypoxia)|go:"GO:0001843"(neural tube closure)|go:"GO:0001933"(negative regulation of protein phosphorylation)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005764"(lysosome)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005901"(caveola)|go:"GO:0006469"(negative regulation of protein kinase activity)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0007165"(signal transduction)|go:"GO:0007507"(heart development)|go:"GO:0007568"(aging)|go:"GO:0008104"(protein localization)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0010508"(positive regulation of autophagy)|go:"GO:0045792"(negative regulation of cell size)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046323"(glucose import)|go:"GO:0046626"(regulation of insulin receptor signaling pathway)|go:"GO:0046627"(negative regulation of insulin receptor signaling pathway)|go:"GO:0047485"(protein N-terminus binding)|go:"GO:0048009"(insulin-like growth factor receptor signaling pathway)|go:"GO:0048147"(negative regulation of fibroblast proliferation)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0048550"(negative regulation of pinocytosis)|go:"GO:0050680"(negative regulation of epithelial cell proliferation)|go:"GO:0050771"(negative regulation of axonogenesis)|go:"GO:0050918"(positive chemotaxis)|go:"GO:0051056"(regulation of small GTPase mediated signal transduction)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0051879"(Hsp90 protein binding)|go:"GO:0051898"(negative regulation of protein kinase B signaling)|go:"GO:0060999"(positive regulation of dendritic spine development)|go:"GO:0071889"(14-3-3 protein binding)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0045785"(positive regulation of cell adhesion)|go:"GO:1904262"(negative regulation of TORC1 signaling)|go:"GO:1905563"(negative regulation of vascular endothelial cell proliferation)|reactome:R-MMU-1632852|reactome:R-MMU-165181|reactome:R-MMU-198323|reactome:R-MMU-380972|reactome:R-MMU-5628897|reactome:R-MMU-8854214|go:"GO:0099175"(regulation of postsynapse organization)|go:"GO:0010763"(positive regulation of fibroblast migration)|go:"GO:0010976"(positive regulation of neuron projection development)|go:"GO:0014065"(phosphatidylinositol 3-kinase signaling)|go:"GO:0014067"(negative regulation of phosphatidylinositol 3-kinase signaling)|go:"GO:0014069"(postsynaptic density)|go:"GO:0016020"(membrane)|go:"GO:0016239"(positive regulation of macroautophagy)|go:"GO:0016242"(negative regulation of macroautophagy)|go:"GO:0019902"(phosphatase binding)|go:"GO:0030010"(establishment of cell polarity)|go:"GO:0030030"(cell projection organization)|go:"GO:0030100"(regulation of endocytosis)|go:"GO:0030178"(negative regulation of Wnt signaling pathway)|go:"GO:0030425"(dendrite)|go:"GO:0010719"(negative regulation of epithelial to mesenchymal transition)|go:"GO:0031267"(small GTPase binding)|go:"GO:0032007"(negative regulation of TOR signaling)|go:"GO:0032869"(cellular response to insulin stimulus)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033596"(TSC1-TSC2 complex)|go:"GO:0034394"(protein localization to cell surface)|go:"GO:0035176"(social behavior)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0042995"(cell projection)|go:"GO:0043005"(neuron projection)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0043276"(anoikis)|go:"GO:0043407"(negative regulation of MAP kinase activity)|go:"GO:0043491"(protein kinase B signaling)|go:"GO:0043547"(positive regulation of GTPase activity)|go:"GO:0044861"(protein transport into plasma membrane raft)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045121"(membrane raft)|go:"GO:0045184"(establishment of protein localization)|go:"GO:0045202"(synapse)|go:"GO:0030426"(growth cone)|interpro:IPR027107|interpro:IPR035974	mint:P9WNI7|interpro:IPR036689|interpro:IPR009416(Protein of unknown function DUF1066)|interpro:IPR010310(Protein of unknown function DUF909)|refseq:NP_216862.1|refseq:WP_003899283.1|go:"GO:0005576"(extracellular region)|go:"GO:0005618"(cell wall)|go:"GO:0005886"(plasma membrane)|rcsb pdb:3OGI|rcsb pdb:4GZR	-	function:Implicated as a tumor suppressor. May have a function in vesicular transport, but may also play a role in the regulation of cell growth arrest and in the regulation of transcription mediated by steroid receptors. Interaction between TSC1 and TSC2 may facilitate vesicular docking. Specifically stimulates the intrinsic GTPase activity of the ras-related protein RAP1A and RAB5. Suggesting a possible mechanism for its role in regulating cellular growth|comment:mint	-	figure legend:ST5|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2020/07/08	2020/08/14	rogid:Sw17BM+O0FRiPsuF0+h8V/MedTM10090	rogid:jYoNmHY+G6+S39CX1qRFCxjy0xw83332	rigid:P+zPXfmr/IqnI03UMG3xZEtSF4M	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q61037	uniprotkb:P9WIT1	intact:EBI-7924402|uniprotkb:Q61007|uniprotkb:Q61008|uniprotkb:P97724|uniprotkb:P97727|uniprotkb:P97725|intact:MINT-5068541|uniprotkb:Q9WUF6|uniprotkb:P97723	intact:EBI-25767539|uniprotkb:L0TBU2|uniprotkb:Q50685|uniprotkb:Q7D7C5	psi-mi:tsc2_mouse(display_long)|uniprotkb:Tuberous sclerosis 2 protein homolog(gene name synonym)|uniprotkb:Tsc2(gene name)|psi-mi:Tsc2(display_short)	psi-mi:y2280_myctu(display_long)|uniprotkb:Rv2280(locus name)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2018)	doi:10.1093/nar/gkx1173|imex:IM-28235|pubmed:29165646	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:83332(myctu)|taxid:83332("Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)")	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0471"(MINT)	intact:EBI-25768604|imex:IM-28235-25	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	interpro:IPR018515|interpro:IPR016024(Armadillo-type fold)|interpro:IPR024584|mint:Q61037|interpro:IPR000331(Rap/ran-GAP)|interpro:IPR003913(Tuberin)|go:"GO:0001666"(response to hypoxia)|go:"GO:0001843"(neural tube closure)|go:"GO:0001933"(negative regulation of protein phosphorylation)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005764"(lysosome)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005901"(caveola)|go:"GO:0006469"(negative regulation of protein kinase activity)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0007165"(signal transduction)|go:"GO:0007507"(heart development)|go:"GO:0007568"(aging)|go:"GO:0008104"(protein localization)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0010508"(positive regulation of autophagy)|go:"GO:0045792"(negative regulation of cell size)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046323"(glucose import)|go:"GO:0046626"(regulation of insulin receptor signaling pathway)|go:"GO:0046627"(negative regulation of insulin receptor signaling pathway)|go:"GO:0047485"(protein N-terminus binding)|go:"GO:0048009"(insulin-like growth factor receptor signaling pathway)|go:"GO:0048147"(negative regulation of fibroblast proliferation)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0048550"(negative regulation of pinocytosis)|go:"GO:0050680"(negative regulation of epithelial cell proliferation)|go:"GO:0050771"(negative regulation of axonogenesis)|go:"GO:0050918"(positive chemotaxis)|go:"GO:0051056"(regulation of small GTPase mediated signal transduction)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0051879"(Hsp90 protein binding)|go:"GO:0051898"(negative regulation of protein kinase B signaling)|go:"GO:0060999"(positive regulation of dendritic spine development)|go:"GO:0071889"(14-3-3 protein binding)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0045785"(positive regulation of cell adhesion)|go:"GO:1904262"(negative regulation of TORC1 signaling)|go:"GO:1905563"(negative regulation of vascular endothelial cell proliferation)|reactome:R-MMU-1632852|reactome:R-MMU-165181|reactome:R-MMU-198323|reactome:R-MMU-380972|reactome:R-MMU-5628897|reactome:R-MMU-8854214|go:"GO:0099175"(regulation of postsynapse organization)|go:"GO:0010763"(positive regulation of fibroblast migration)|go:"GO:0010976"(positive regulation of neuron projection development)|go:"GO:0014065"(phosphatidylinositol 3-kinase signaling)|go:"GO:0014067"(negative regulation of phosphatidylinositol 3-kinase signaling)|go:"GO:0014069"(postsynaptic density)|go:"GO:0016020"(membrane)|go:"GO:0016239"(positive regulation of macroautophagy)|go:"GO:0016242"(negative regulation of macroautophagy)|go:"GO:0019902"(phosphatase binding)|go:"GO:0030010"(establishment of cell polarity)|go:"GO:0030030"(cell projection organization)|go:"GO:0030100"(regulation of endocytosis)|go:"GO:0030178"(negative regulation of Wnt signaling pathway)|go:"GO:0030425"(dendrite)|go:"GO:0010719"(negative regulation of epithelial to mesenchymal transition)|go:"GO:0031267"(small GTPase binding)|go:"GO:0032007"(negative regulation of TOR signaling)|go:"GO:0032869"(cellular response to insulin stimulus)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033596"(TSC1-TSC2 complex)|go:"GO:0034394"(protein localization to cell surface)|go:"GO:0035176"(social behavior)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0042995"(cell projection)|go:"GO:0043005"(neuron projection)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0043276"(anoikis)|go:"GO:0043407"(negative regulation of MAP kinase activity)|go:"GO:0043491"(protein kinase B signaling)|go:"GO:0043547"(positive regulation of GTPase activity)|go:"GO:0044861"(protein transport into plasma membrane raft)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045121"(membrane raft)|go:"GO:0045184"(establishment of protein localization)|go:"GO:0045202"(synapse)|go:"GO:0030426"(growth cone)|interpro:IPR027107|interpro:IPR035974	go:"GO:0005618"(cell wall)|go:"GO:0005886"(plasma membrane)|go:"GO:0016491"(oxidoreductase activity)|go:"GO:0071949"(FAD binding)|interpro:IPR016169(CO dehydrogenase flavoprotein-like, FAD-binding, subdomain 2)|mint:P9WIT1|refseq:WP_003411690.1|interpro:IPR016166(FAD-binding, type 2)|interpro:IPR036318|interpro:IPR016164(FAD-linked oxidase-like, C-terminal)|interpro:IPR004113(FAD-linked oxidase, C-terminal)|interpro:IPR006094(FAD linked oxidase, N-terminal)|interpro:IPR016171(Vanillyl-alcohol oxidase, C-terminal subdomain 2)	-	function:Implicated as a tumor suppressor. May have a function in vesicular transport, but may also play a role in the regulation of cell growth arrest and in the regulation of transcription mediated by steroid receptors. Interaction between TSC1 and TSC2 may facilitate vesicular docking. Specifically stimulates the intrinsic GTPase activity of the ras-related protein RAP1A and RAB5. Suggesting a possible mechanism for its role in regulating cellular growth|comment:mint	-	figure legend:ST5|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2020/07/08	2020/08/14	rogid:Sw17BM+O0FRiPsuF0+h8V/MedTM10090	rogid:TvFI3uuw9zREl1q0DeWIsHmCSEk83332	rigid:gbZJ7qbLHtzRPBrb9ksnn27Sk74	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q61037	uniprotkb:L7N684	intact:EBI-7924402|uniprotkb:Q61007|uniprotkb:Q61008|uniprotkb:P97724|uniprotkb:P97727|uniprotkb:P97725|intact:MINT-5068541|uniprotkb:Q9WUF6|uniprotkb:P97723	intact:EBI-25768007|uniprotkb:I6XZY1	psi-mi:tsc2_mouse(display_long)|uniprotkb:Tuberous sclerosis 2 protein homolog(gene name synonym)|uniprotkb:Tsc2(gene name)|psi-mi:Tsc2(display_short)	psi-mi:l7n684_myctu(display_long)|uniprotkb:Rv2141c(locus name)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2018)	doi:10.1093/nar/gkx1173|imex:IM-28235|pubmed:29165646	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:83332(myctu)|taxid:83332("Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)")	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0471"(MINT)	intact:EBI-25768598|imex:IM-28235-331	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	interpro:IPR018515|interpro:IPR016024(Armadillo-type fold)|interpro:IPR024584|mint:Q61037|interpro:IPR000331(Rap/ran-GAP)|interpro:IPR003913(Tuberin)|go:"GO:0001666"(response to hypoxia)|go:"GO:0001843"(neural tube closure)|go:"GO:0001933"(negative regulation of protein phosphorylation)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005764"(lysosome)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005901"(caveola)|go:"GO:0006469"(negative regulation of protein kinase activity)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0007165"(signal transduction)|go:"GO:0007507"(heart development)|go:"GO:0007568"(aging)|go:"GO:0008104"(protein localization)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0010508"(positive regulation of autophagy)|go:"GO:0045792"(negative regulation of cell size)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046323"(glucose import)|go:"GO:0046626"(regulation of insulin receptor signaling pathway)|go:"GO:0046627"(negative regulation of insulin receptor signaling pathway)|go:"GO:0047485"(protein N-terminus binding)|go:"GO:0048009"(insulin-like growth factor receptor signaling pathway)|go:"GO:0048147"(negative regulation of fibroblast proliferation)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0048550"(negative regulation of pinocytosis)|go:"GO:0050680"(negative regulation of epithelial cell proliferation)|go:"GO:0050771"(negative regulation of axonogenesis)|go:"GO:0050918"(positive chemotaxis)|go:"GO:0051056"(regulation of small GTPase mediated signal transduction)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0051879"(Hsp90 protein binding)|go:"GO:0051898"(negative regulation of protein kinase B signaling)|go:"GO:0060999"(positive regulation of dendritic spine development)|go:"GO:0071889"(14-3-3 protein binding)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0045785"(positive regulation of cell adhesion)|go:"GO:1904262"(negative regulation of TORC1 signaling)|go:"GO:1905563"(negative regulation of vascular endothelial cell proliferation)|reactome:R-MMU-1632852|reactome:R-MMU-165181|reactome:R-MMU-198323|reactome:R-MMU-380972|reactome:R-MMU-5628897|reactome:R-MMU-8854214|go:"GO:0099175"(regulation of postsynapse organization)|go:"GO:0010763"(positive regulation of fibroblast migration)|go:"GO:0010976"(positive regulation of neuron projection development)|go:"GO:0014065"(phosphatidylinositol 3-kinase signaling)|go:"GO:0014067"(negative regulation of phosphatidylinositol 3-kinase signaling)|go:"GO:0014069"(postsynaptic density)|go:"GO:0016020"(membrane)|go:"GO:0016239"(positive regulation of macroautophagy)|go:"GO:0016242"(negative regulation of macroautophagy)|go:"GO:0019902"(phosphatase binding)|go:"GO:0030010"(establishment of cell polarity)|go:"GO:0030030"(cell projection organization)|go:"GO:0030100"(regulation of endocytosis)|go:"GO:0030178"(negative regulation of Wnt signaling pathway)|go:"GO:0030425"(dendrite)|go:"GO:0010719"(negative regulation of epithelial to mesenchymal transition)|go:"GO:0031267"(small GTPase binding)|go:"GO:0032007"(negative regulation of TOR signaling)|go:"GO:0032869"(cellular response to insulin stimulus)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033596"(TSC1-TSC2 complex)|go:"GO:0034394"(protein localization to cell surface)|go:"GO:0035176"(social behavior)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0042995"(cell projection)|go:"GO:0043005"(neuron projection)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0043276"(anoikis)|go:"GO:0043407"(negative regulation of MAP kinase activity)|go:"GO:0043491"(protein kinase B signaling)|go:"GO:0043547"(positive regulation of GTPase activity)|go:"GO:0044861"(protein transport into plasma membrane raft)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045121"(membrane raft)|go:"GO:0045184"(establishment of protein localization)|go:"GO:0045202"(synapse)|go:"GO:0030426"(growth cone)|interpro:IPR027107|interpro:IPR035974	go:"GO:0006526"(arginine biosynthetic process)|go:"GO:0008777"(acetylornithine deacetylase activity)|mint:L7N684|refseq:WP_003411121.1|refseq:YP_177864.1|interpro:IPR001261(ArgE/DapE/ACY1/CPG2/YscS, conserved site)|interpro:IPR036264|interpro:IPR002933(Peptidase M20)|interpro:IPR011650(Peptidase M20, dimerisation)	-	function:Implicated as a tumor suppressor. May have a function in vesicular transport, but may also play a role in the regulation of cell growth arrest and in the regulation of transcription mediated by steroid receptors. Interaction between TSC1 and TSC2 may facilitate vesicular docking. Specifically stimulates the intrinsic GTPase activity of the ras-related protein RAP1A and RAB5. Suggesting a possible mechanism for its role in regulating cellular growth|comment:mint	-	figure legend:ST5|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2020/07/08	2020/08/14	rogid:Sw17BM+O0FRiPsuF0+h8V/MedTM10090	rogid:c/gr5TMeB+nx0CZHLBZI7YeVioo83332	rigid:xVFovFdfVzrMgebOTH4bfV9Q5oU	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q61037	uniprotkb:P9WN37	intact:EBI-7924402|uniprotkb:Q61007|uniprotkb:Q61008|uniprotkb:P97724|uniprotkb:P97727|uniprotkb:P97725|intact:MINT-5068541|uniprotkb:Q9WUF6|uniprotkb:P97723	intact:EBI-25767601|uniprotkb:L0T968|uniprotkb:P64245|uniprotkb:Q10378	psi-mi:tsc2_mouse(display_long)|uniprotkb:Tuberous sclerosis 2 protein homolog(gene name synonym)|uniprotkb:Tsc2(gene name)|psi-mi:Tsc2(display_short)	psi-mi:gln1a_myctu(display_long)|uniprotkb:glnA2(gene name)|psi-mi:glnA2(display_short)|uniprotkb:Glutamate--ammonia ligase(gene name synonym)|uniprotkb:Glutamine synthetase I alpha(gene name synonym)|uniprotkb:MTCY190.33c(orf name)|uniprotkb:MTCY427.03c(orf name)|uniprotkb:Rv2222c(locus name)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2018)	doi:10.1093/nar/gkx1173|imex:IM-28235|pubmed:29165646	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:83332(myctu)|taxid:83332("Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)")	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0471"(MINT)	intact:EBI-25768592|imex:IM-28235-97	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	interpro:IPR018515|interpro:IPR016024(Armadillo-type fold)|interpro:IPR024584|mint:Q61037|interpro:IPR000331(Rap/ran-GAP)|interpro:IPR003913(Tuberin)|go:"GO:0001666"(response to hypoxia)|go:"GO:0001843"(neural tube closure)|go:"GO:0001933"(negative regulation of protein phosphorylation)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005764"(lysosome)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005901"(caveola)|go:"GO:0006469"(negative regulation of protein kinase activity)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0007165"(signal transduction)|go:"GO:0007507"(heart development)|go:"GO:0007568"(aging)|go:"GO:0008104"(protein localization)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0010508"(positive regulation of autophagy)|go:"GO:0045792"(negative regulation of cell size)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046323"(glucose import)|go:"GO:0046626"(regulation of insulin receptor signaling pathway)|go:"GO:0046627"(negative regulation of insulin receptor signaling pathway)|go:"GO:0047485"(protein N-terminus binding)|go:"GO:0048009"(insulin-like growth factor receptor signaling pathway)|go:"GO:0048147"(negative regulation of fibroblast proliferation)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0048550"(negative regulation of pinocytosis)|go:"GO:0050680"(negative regulation of epithelial cell proliferation)|go:"GO:0050771"(negative regulation of axonogenesis)|go:"GO:0050918"(positive chemotaxis)|go:"GO:0051056"(regulation of small GTPase mediated signal transduction)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0051879"(Hsp90 protein binding)|go:"GO:0051898"(negative regulation of protein kinase B signaling)|go:"GO:0060999"(positive regulation of dendritic spine development)|go:"GO:0071889"(14-3-3 protein binding)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0045785"(positive regulation of cell adhesion)|go:"GO:1904262"(negative regulation of TORC1 signaling)|go:"GO:1905563"(negative regulation of vascular endothelial cell proliferation)|reactome:R-MMU-1632852|reactome:R-MMU-165181|reactome:R-MMU-198323|reactome:R-MMU-380972|reactome:R-MMU-5628897|reactome:R-MMU-8854214|go:"GO:0099175"(regulation of postsynapse organization)|go:"GO:0010763"(positive regulation of fibroblast migration)|go:"GO:0010976"(positive regulation of neuron projection development)|go:"GO:0014065"(phosphatidylinositol 3-kinase signaling)|go:"GO:0014067"(negative regulation of phosphatidylinositol 3-kinase signaling)|go:"GO:0014069"(postsynaptic density)|go:"GO:0016020"(membrane)|go:"GO:0016239"(positive regulation of macroautophagy)|go:"GO:0016242"(negative regulation of macroautophagy)|go:"GO:0019902"(phosphatase binding)|go:"GO:0030010"(establishment of cell polarity)|go:"GO:0030030"(cell projection organization)|go:"GO:0030100"(regulation of endocytosis)|go:"GO:0030178"(negative regulation of Wnt signaling pathway)|go:"GO:0030425"(dendrite)|go:"GO:0010719"(negative regulation of epithelial to mesenchymal transition)|go:"GO:0031267"(small GTPase binding)|go:"GO:0032007"(negative regulation of TOR signaling)|go:"GO:0032869"(cellular response to insulin stimulus)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033596"(TSC1-TSC2 complex)|go:"GO:0034394"(protein localization to cell surface)|go:"GO:0035176"(social behavior)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0042995"(cell projection)|go:"GO:0043005"(neuron projection)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0043276"(anoikis)|go:"GO:0043407"(negative regulation of MAP kinase activity)|go:"GO:0043491"(protein kinase B signaling)|go:"GO:0043547"(positive regulation of GTPase activity)|go:"GO:0044861"(protein transport into plasma membrane raft)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045121"(membrane raft)|go:"GO:0045184"(establishment of protein localization)|go:"GO:0045202"(synapse)|go:"GO:0030426"(growth cone)|interpro:IPR027107|interpro:IPR035974	go:"GO:0004356"(glutamate-ammonia ligase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0006542"(glutamine biosynthetic process)|go:"GO:0046872"(metal ion binding)|go:"GO:0050001"(D-glutaminase activity)|mint:P9WN37|refseq:NP_216738.1|refseq:WP_003411482.1|interpro:IPR008147(Glutamine synthetase, beta-Grasp)|interpro:IPR036651|interpro:IPR014746(Glutamine synthetase/guanido kinase, catalytic region)|interpro:IPR008146(Glutamine synthetase, catalytic region)|interpro:IPR027303	-	function:Implicated as a tumor suppressor. May have a function in vesicular transport, but may also play a role in the regulation of cell growth arrest and in the regulation of transcription mediated by steroid receptors. Interaction between TSC1 and TSC2 may facilitate vesicular docking. Specifically stimulates the intrinsic GTPase activity of the ras-related protein RAP1A and RAB5. Suggesting a possible mechanism for its role in regulating cellular growth|comment:mint	-	figure legend:ST5|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2020/07/08	2020/08/14	rogid:Sw17BM+O0FRiPsuF0+h8V/MedTM10090	rogid:LDIpolmw5yhv2iG5+8HKbWlwT8883332	rigid:pj+Hi4aR/Ot/DpAXsbzj/LpMndw	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q61037	uniprotkb:P71619	intact:EBI-7924402|uniprotkb:Q61007|uniprotkb:Q61008|uniprotkb:P97724|uniprotkb:P97727|uniprotkb:P97725|intact:MINT-5068541|uniprotkb:Q9WUF6|uniprotkb:P97723	intact:EBI-25767582|uniprotkb:F2GLA0|uniprotkb:I6YAD4	psi-mi:tsc2_mouse(display_long)|uniprotkb:Tuberous sclerosis 2 protein homolog(gene name synonym)|uniprotkb:Tsc2(gene name)|psi-mi:Tsc2(display_short)	psi-mi:p71619_myctu(display_long)|uniprotkb:ugpB(gene name)|psi-mi:ugpB(display_short)|uniprotkb:Rv2833c(locus name)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2018)	doi:10.1093/nar/gkx1173|imex:IM-28235|pubmed:29165646	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:83332(myctu)|taxid:83332("Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)")	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0471"(MINT)	intact:EBI-25768586|imex:IM-28235-289	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	interpro:IPR018515|interpro:IPR016024(Armadillo-type fold)|interpro:IPR024584|mint:Q61037|interpro:IPR000331(Rap/ran-GAP)|interpro:IPR003913(Tuberin)|go:"GO:0001666"(response to hypoxia)|go:"GO:0001843"(neural tube closure)|go:"GO:0001933"(negative regulation of protein phosphorylation)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005764"(lysosome)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005901"(caveola)|go:"GO:0006469"(negative regulation of protein kinase activity)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0007165"(signal transduction)|go:"GO:0007507"(heart development)|go:"GO:0007568"(aging)|go:"GO:0008104"(protein localization)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0010508"(positive regulation of autophagy)|go:"GO:0045792"(negative regulation of cell size)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046323"(glucose import)|go:"GO:0046626"(regulation of insulin receptor signaling pathway)|go:"GO:0046627"(negative regulation of insulin receptor signaling pathway)|go:"GO:0047485"(protein N-terminus binding)|go:"GO:0048009"(insulin-like growth factor receptor signaling pathway)|go:"GO:0048147"(negative regulation of fibroblast proliferation)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0048550"(negative regulation of pinocytosis)|go:"GO:0050680"(negative regulation of epithelial cell proliferation)|go:"GO:0050771"(negative regulation of axonogenesis)|go:"GO:0050918"(positive chemotaxis)|go:"GO:0051056"(regulation of small GTPase mediated signal transduction)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0051879"(Hsp90 protein binding)|go:"GO:0051898"(negative regulation of protein kinase B signaling)|go:"GO:0060999"(positive regulation of dendritic spine development)|go:"GO:0071889"(14-3-3 protein binding)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0045785"(positive regulation of cell adhesion)|go:"GO:1904262"(negative regulation of TORC1 signaling)|go:"GO:1905563"(negative regulation of vascular endothelial cell proliferation)|reactome:R-MMU-1632852|reactome:R-MMU-165181|reactome:R-MMU-198323|reactome:R-MMU-380972|reactome:R-MMU-5628897|reactome:R-MMU-8854214|go:"GO:0099175"(regulation of postsynapse organization)|go:"GO:0010763"(positive regulation of fibroblast migration)|go:"GO:0010976"(positive regulation of neuron projection development)|go:"GO:0014065"(phosphatidylinositol 3-kinase signaling)|go:"GO:0014067"(negative regulation of phosphatidylinositol 3-kinase signaling)|go:"GO:0014069"(postsynaptic density)|go:"GO:0016020"(membrane)|go:"GO:0016239"(positive regulation of macroautophagy)|go:"GO:0016242"(negative regulation of macroautophagy)|go:"GO:0019902"(phosphatase binding)|go:"GO:0030010"(establishment of cell polarity)|go:"GO:0030030"(cell projection organization)|go:"GO:0030100"(regulation of endocytosis)|go:"GO:0030178"(negative regulation of Wnt signaling pathway)|go:"GO:0030425"(dendrite)|go:"GO:0010719"(negative regulation of epithelial to mesenchymal transition)|go:"GO:0031267"(small GTPase binding)|go:"GO:0032007"(negative regulation of TOR signaling)|go:"GO:0032869"(cellular response to insulin stimulus)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033596"(TSC1-TSC2 complex)|go:"GO:0034394"(protein localization to cell surface)|go:"GO:0035176"(social behavior)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0042995"(cell projection)|go:"GO:0043005"(neuron projection)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0043276"(anoikis)|go:"GO:0043407"(negative regulation of MAP kinase activity)|go:"GO:0043491"(protein kinase B signaling)|go:"GO:0043547"(positive regulation of GTPase activity)|go:"GO:0044861"(protein transport into plasma membrane raft)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045121"(membrane raft)|go:"GO:0045184"(establishment of protein localization)|go:"GO:0045202"(synapse)|go:"GO:0030426"(growth cone)|interpro:IPR027107|interpro:IPR035974	go:"GO:0005886"(plasma membrane)|rcsb pdb:6R1B|mint:P71619|refseq:NP_217349.1|refseq:WP_003414501.1|interpro:IPR006059(Bacterial extracellular solute-binding, family 1)|interpro:IPR006311(Twin-arginine translocation pathway signal)	-	function:Implicated as a tumor suppressor. May have a function in vesicular transport, but may also play a role in the regulation of cell growth arrest and in the regulation of transcription mediated by steroid receptors. Interaction between TSC1 and TSC2 may facilitate vesicular docking. Specifically stimulates the intrinsic GTPase activity of the ras-related protein RAP1A and RAB5. Suggesting a possible mechanism for its role in regulating cellular growth|comment:mint	-	figure legend:ST5|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2020/07/08	2020/08/14	rogid:Sw17BM+O0FRiPsuF0+h8V/MedTM10090	rogid:ldo4FA/3ddzSo1mfnNEPte27F1083332	rigid:No3q+xAbbWkqp2W4EIyRvlPyNU8	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P9WN37	uniprotkb:P70315	intact:EBI-25767601|uniprotkb:L0T968|uniprotkb:P64245|uniprotkb:Q10378	intact:EBI-644195|ensembl:ENSMUSP00000033505	psi-mi:gln1a_myctu(display_long)|uniprotkb:glnA2(gene name)|psi-mi:glnA2(display_short)|uniprotkb:Glutamate--ammonia ligase(gene name synonym)|uniprotkb:Glutamine synthetase I alpha(gene name synonym)|uniprotkb:MTCY190.33c(orf name)|uniprotkb:MTCY427.03c(orf name)|uniprotkb:Rv2222c(locus name)	psi-mi:wasp_mouse(display_long)|uniprotkb:Was(gene name)|psi-mi:Was(display_short)|uniprotkb:Wasp(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2018)	doi:10.1093/nar/gkx1173|imex:IM-28235|pubmed:29165646	taxid:83332(myctu)|taxid:83332("Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)")	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0471"(MINT)	intact:EBI-25768850|imex:IM-28235-217	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	go:"GO:0004356"(glutamate-ammonia ligase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0006542"(glutamine biosynthetic process)|go:"GO:0046872"(metal ion binding)|go:"GO:0050001"(D-glutaminase activity)|mint:P9WN37|refseq:NP_216738.1|refseq:WP_003411482.1|interpro:IPR008147(Glutamine synthetase, beta-Grasp)|interpro:IPR036651|interpro:IPR014746(Glutamine synthetase/guanido kinase, catalytic region)|interpro:IPR008146(Glutamine synthetase, catalytic region)|interpro:IPR027303	refseq:NP_033541.1|ensembl:ENSMUSG00000031165(gene)|ensembl:ENSMUST00000033505(transcript)|go:"GO:0002625"(regulation of T cell antigen processing and presentation)|go:"GO:0003779"(actin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0005884"(actin filament)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0006955"(immune response)|go:"GO:0008064"(regulation of actin polymerization or depolymerization)|go:"GO:0008154"(actin polymerization or depolymerization)|go:"GO:0010591"(regulation of lamellipodium assembly)|go:"GO:0012506"(vesicle membrane)|go:"GO:0016197"(endosomal transport)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030041"(actin filament polymerization)|go:"GO:0030048"(actin filament-based movement)|go:"GO:0031267"(small GTPase binding)|go:"GO:0032488"(Cdc42 protein signal transduction)|go:"GO:0035861"(site of double-strand break)|go:"GO:0042110"(T cell activation)|go:"GO:0042802"(identical protein binding)|go:"GO:0043274"(phospholipase binding)|go:"GO:0045335"(phagocytic vesicle)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0051492"(regulation of stress fiber assembly)|go:"GO:0051497"(negative regulation of stress fiber assembly)|go:"GO:0071346"(cellular response to interferon-gamma)|go:"GO:1905168"(positive regulation of double-strand break repair via homologous recombination)|go:"GO:2000146"(negative regulation of cell motility)|go:"GO:2000601"(positive regulation of Arp2/3 complex-mediated actin nucleation)|interpro:IPR000095(PAK-box/P21-Rho-binding)|interpro:IPR000697(EVH1)|interpro:IPR003124(Actin-binding WH2)|interpro:IPR011026(Wiscott-Aldrich syndrome, C-terminal)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR027641|interpro:IPR033927|interpro:IPR036936|mint:P70315|dip:DIP-36426N	-	-	-	figure legend:ST5|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2020/07/08	2020/08/14	rogid:LDIpolmw5yhv2iG5+8HKbWlwT8883332	rogid:HbZjGXPVByZsiabjyX43YwKnJeA10090	rigid:xeQowtWkr7t3wery5HsRhB0szLk	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P71619	uniprotkb:P70315	intact:EBI-25767582|uniprotkb:F2GLA0|uniprotkb:I6YAD4	intact:EBI-644195|ensembl:ENSMUSP00000033505	psi-mi:p71619_myctu(display_long)|uniprotkb:ugpB(gene name)|psi-mi:ugpB(display_short)|uniprotkb:Rv2833c(locus name)	psi-mi:wasp_mouse(display_long)|uniprotkb:Was(gene name)|psi-mi:Was(display_short)|uniprotkb:Wasp(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2018)	doi:10.1093/nar/gkx1173|imex:IM-28235|pubmed:29165646	taxid:83332(myctu)|taxid:83332("Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)")	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0471"(MINT)	intact:EBI-25768844|imex:IM-28235-299	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	go:"GO:0005886"(plasma membrane)|rcsb pdb:6R1B|mint:P71619|refseq:NP_217349.1|refseq:WP_003414501.1|interpro:IPR006059(Bacterial extracellular solute-binding, family 1)|interpro:IPR006311(Twin-arginine translocation pathway signal)	refseq:NP_033541.1|ensembl:ENSMUSG00000031165(gene)|ensembl:ENSMUST00000033505(transcript)|go:"GO:0002625"(regulation of T cell antigen processing and presentation)|go:"GO:0003779"(actin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0005884"(actin filament)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0006955"(immune response)|go:"GO:0008064"(regulation of actin polymerization or depolymerization)|go:"GO:0008154"(actin polymerization or depolymerization)|go:"GO:0010591"(regulation of lamellipodium assembly)|go:"GO:0012506"(vesicle membrane)|go:"GO:0016197"(endosomal transport)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030041"(actin filament polymerization)|go:"GO:0030048"(actin filament-based movement)|go:"GO:0031267"(small GTPase binding)|go:"GO:0032488"(Cdc42 protein signal transduction)|go:"GO:0035861"(site of double-strand break)|go:"GO:0042110"(T cell activation)|go:"GO:0042802"(identical protein binding)|go:"GO:0043274"(phospholipase binding)|go:"GO:0045335"(phagocytic vesicle)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0051492"(regulation of stress fiber assembly)|go:"GO:0051497"(negative regulation of stress fiber assembly)|go:"GO:0071346"(cellular response to interferon-gamma)|go:"GO:1905168"(positive regulation of double-strand break repair via homologous recombination)|go:"GO:2000146"(negative regulation of cell motility)|go:"GO:2000601"(positive regulation of Arp2/3 complex-mediated actin nucleation)|interpro:IPR000095(PAK-box/P21-Rho-binding)|interpro:IPR000697(EVH1)|interpro:IPR003124(Actin-binding WH2)|interpro:IPR011026(Wiscott-Aldrich syndrome, C-terminal)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR027641|interpro:IPR033927|interpro:IPR036936|mint:P70315|dip:DIP-36426N	-	-	-	figure legend:ST5|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2020/07/08	2020/08/14	rogid:ldo4FA/3ddzSo1mfnNEPte27F1083332	rogid:HbZjGXPVByZsiabjyX43YwKnJeA10090	rigid:HGYSffkpyp7LEXUjSXLjlJxKXdw	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:O69689	uniprotkb:P70315	intact:EBI-25767781|uniprotkb:F2GFU4|uniprotkb:I6Y4D4|uniprotkb:Q7D501	intact:EBI-644195|ensembl:ENSMUSP00000033505	psi-mi:aspat_myctu(display_long)|uniprotkb:Rv3722c(locus name)	psi-mi:wasp_mouse(display_long)|uniprotkb:Was(gene name)|psi-mi:Was(display_short)|uniprotkb:Wasp(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2018)	doi:10.1093/nar/gkx1173|imex:IM-28235|pubmed:29165646	taxid:83332(myctu)|taxid:83332("Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)")	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0471"(MINT)	intact:EBI-25768838|imex:IM-28235-277	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	go:"GO:0004069"("L-aspartate:2-oxoglutarate aminotransferase activity")|go:"GO:0005576"(extracellular region)|rcsb pdb:5C6U|rcsb pdb:6U78|rcsb pdb:6U7A|mint:O69689|refseq:NP_218239.2|refseq:WP_003899653.1|interpro:IPR024551|interpro:IPR015424(Pyridoxal phosphate-dependent transferase, major region)|interpro:IPR015422(Pyridoxal phosphate-dependent transferase, major region, subdomain 2)|interpro:IPR015421(Pyridoxal phosphate-dependent transferase, major region, subdomain 1)	refseq:NP_033541.1|ensembl:ENSMUSG00000031165(gene)|ensembl:ENSMUST00000033505(transcript)|go:"GO:0002625"(regulation of T cell antigen processing and presentation)|go:"GO:0003779"(actin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0005884"(actin filament)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0006955"(immune response)|go:"GO:0008064"(regulation of actin polymerization or depolymerization)|go:"GO:0008154"(actin polymerization or depolymerization)|go:"GO:0010591"(regulation of lamellipodium assembly)|go:"GO:0012506"(vesicle membrane)|go:"GO:0016197"(endosomal transport)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030041"(actin filament polymerization)|go:"GO:0030048"(actin filament-based movement)|go:"GO:0031267"(small GTPase binding)|go:"GO:0032488"(Cdc42 protein signal transduction)|go:"GO:0035861"(site of double-strand break)|go:"GO:0042110"(T cell activation)|go:"GO:0042802"(identical protein binding)|go:"GO:0043274"(phospholipase binding)|go:"GO:0045335"(phagocytic vesicle)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0051492"(regulation of stress fiber assembly)|go:"GO:0051497"(negative regulation of stress fiber assembly)|go:"GO:0071346"(cellular response to interferon-gamma)|go:"GO:1905168"(positive regulation of double-strand break repair via homologous recombination)|go:"GO:2000146"(negative regulation of cell motility)|go:"GO:2000601"(positive regulation of Arp2/3 complex-mediated actin nucleation)|interpro:IPR000095(PAK-box/P21-Rho-binding)|interpro:IPR000697(EVH1)|interpro:IPR003124(Actin-binding WH2)|interpro:IPR011026(Wiscott-Aldrich syndrome, C-terminal)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR027641|interpro:IPR033927|interpro:IPR036936|mint:P70315|dip:DIP-36426N	-	-	-	figure legend:ST5|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2020/07/08	2020/08/14	rogid:TGWnUCrIwLrRrMnna5+/w33GpgA83332	rogid:HbZjGXPVByZsiabjyX43YwKnJeA10090	rigid:80yTVZt5Oh5k6R1AqvRGvKAPpN8	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:O69689	uniprotkb:Q8K245	intact:EBI-25767781|uniprotkb:F2GFU4|uniprotkb:I6Y4D4|uniprotkb:Q7D501	intact:EBI-6678333|ensembl:ENSMUSP00000045297|intact:EBI-10689401|uniprotkb:Q8BVI8|uniprotkb:Q8C0K8	psi-mi:aspat_myctu(display_long)|uniprotkb:Rv3722c(locus name)	psi-mi:uvrag_mouse(display_long)|uniprotkb:Uvrag1(gene name synonym)|uniprotkb:Uvrag(gene name)|psi-mi:Uvrag(display_short)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2018)	doi:10.1093/nar/gkx1173|imex:IM-28235|pubmed:29165646	taxid:83332(myctu)|taxid:83332("Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)")	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0471"(MINT)	intact:EBI-25768832|imex:IM-28235-59	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	go:"GO:0004069"("L-aspartate:2-oxoglutarate aminotransferase activity")|go:"GO:0005576"(extracellular region)|rcsb pdb:5C6U|rcsb pdb:6U78|rcsb pdb:6U7A|mint:O69689|refseq:NP_218239.2|refseq:WP_003899653.1|interpro:IPR024551|interpro:IPR015424(Pyridoxal phosphate-dependent transferase, major region)|interpro:IPR015422(Pyridoxal phosphate-dependent transferase, major region, subdomain 2)|interpro:IPR015421(Pyridoxal phosphate-dependent transferase, major region, subdomain 1)	ensembl:ENSMUSG00000035354(gene)|ensembl:ENSMUST00000037968(transcript)|go:"GO:0000149"(SNARE binding)|go:"GO:0000323"(lytic vacuole)|go:"GO:0000421"(autophagosome membrane)|go:"GO:0000775"(chromosome, centromeric region)|go:"GO:0005764"(lysosome)|go:"GO:0005768"(endosome)|go:"GO:0005769"(early endosome)|go:"GO:0005770"(late endosome)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005813"(centrosome)|go:"GO:0006281"(DNA repair)|go:"GO:0006890"(retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum)|go:"GO:0006914"(autophagy)|go:"GO:0007051"(spindle organization)|go:"GO:0007059"(chromosome segregation)|go:"GO:0007098"(centrosome cycle)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0030496"(midbody)|go:"GO:0032465"(regulation of cytokinesis)|go:"GO:0032801"(receptor catabolic process)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035493"(SNARE complex assembly)|go:"GO:0045335"(phagocytic vesicle)|go:"GO:0046718"(viral entry into host cell)|go:"GO:0051684"(maintenance of Golgi location)|go:"GO:0070418"(DNA-dependent protein kinase complex)|go:"GO:0071900"(regulation of protein serine/threonine kinase activity)|go:"GO:0097352"(autophagosome maturation)|go:"GO:0097680"(double-strand break repair via classical nonhomologous end joining)|interpro:IPR000008(C2 calcium-dependent membrane targeting)|interpro:IPR018791|interpro:IPR035892|mint:Q8K245|rcsb pdb:5YR0|reactome:R-MMU-1632852|refseq:NP_848750.3	-	-	-	figure legend:ST5|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2020/07/08	2020/08/14	rogid:TGWnUCrIwLrRrMnna5+/w33GpgA83332	rogid:rzFzOhdqb0elqRBuF+JOh7I3AsI10090	rigid:NitvcMNNwRHzdsqYYIH4kJCeFTg	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:O53319	uniprotkb:Q8K245	intact:EBI-25767766|uniprotkb:I6X6K2|uniprotkb:L0TEH7	intact:EBI-6678333|ensembl:ENSMUSP00000045297|intact:EBI-10689401|uniprotkb:Q8BVI8|uniprotkb:Q8C0K8	psi-mi:o53319_myctu(display_long)|uniprotkb:Rv3169(locus name)	psi-mi:uvrag_mouse(display_long)|uniprotkb:Uvrag1(gene name synonym)|uniprotkb:Uvrag(gene name)|psi-mi:Uvrag(display_short)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2018)	doi:10.1093/nar/gkx1173|imex:IM-28235|pubmed:29165646	taxid:83332(myctu)|taxid:83332("Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)")	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0471"(MINT)	intact:EBI-25768826|imex:IM-28235-39	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	go:"GO:0005886"(plasma membrane)|mint:O53319|refseq:NP_217685.1|refseq:WP_003416605.1	ensembl:ENSMUSG00000035354(gene)|ensembl:ENSMUST00000037968(transcript)|go:"GO:0000149"(SNARE binding)|go:"GO:0000323"(lytic vacuole)|go:"GO:0000421"(autophagosome membrane)|go:"GO:0000775"(chromosome, centromeric region)|go:"GO:0005764"(lysosome)|go:"GO:0005768"(endosome)|go:"GO:0005769"(early endosome)|go:"GO:0005770"(late endosome)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005813"(centrosome)|go:"GO:0006281"(DNA repair)|go:"GO:0006890"(retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum)|go:"GO:0006914"(autophagy)|go:"GO:0007051"(spindle organization)|go:"GO:0007059"(chromosome segregation)|go:"GO:0007098"(centrosome cycle)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0030496"(midbody)|go:"GO:0032465"(regulation of cytokinesis)|go:"GO:0032801"(receptor catabolic process)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035493"(SNARE complex assembly)|go:"GO:0045335"(phagocytic vesicle)|go:"GO:0046718"(viral entry into host cell)|go:"GO:0051684"(maintenance of Golgi location)|go:"GO:0070418"(DNA-dependent protein kinase complex)|go:"GO:0071900"(regulation of protein serine/threonine kinase activity)|go:"GO:0097352"(autophagosome maturation)|go:"GO:0097680"(double-strand break repair via classical nonhomologous end joining)|interpro:IPR000008(C2 calcium-dependent membrane targeting)|interpro:IPR018791|interpro:IPR035892|mint:Q8K245|rcsb pdb:5YR0|reactome:R-MMU-1632852|refseq:NP_848750.3	-	-	-	figure legend:ST5|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2020/07/08	2020/08/14	rogid:Gd1O5B5qTAQflXzn9MR+6fgqvDs83332	rogid:rzFzOhdqb0elqRBuF+JOh7I3AsI10090	rigid:D5QL0kN5znbBKPrwf+1T38IbIzg	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:O50440	uniprotkb:Q8K245	intact:EBI-25767742|uniprotkb:I6XXB2|uniprotkb:L0T7J5	intact:EBI-6678333|ensembl:ENSMUSP00000045297|intact:EBI-10689401|uniprotkb:Q8BVI8|uniprotkb:Q8C0K8	psi-mi:chp2_myctu(display_long)|uniprotkb:chp2(gene name)|psi-mi:chp2(display_short)|uniprotkb:LH57_06500(orf name)|uniprotkb:P425_01234(orf name)|uniprotkb:Rv1184c(locus name)|uniprotkb:RVBD_1184c(locus name)	psi-mi:uvrag_mouse(display_long)|uniprotkb:Uvrag1(gene name synonym)|uniprotkb:Uvrag(gene name)|psi-mi:Uvrag(display_short)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2018)	doi:10.1093/nar/gkx1173|imex:IM-28235|pubmed:29165646	taxid:83332(myctu)|taxid:83332("Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)")	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0471"(MINT)	intact:EBI-25768820|imex:IM-28235-37	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	go:"GO:0005886"(plasma membrane)|go:"GO:0006629"(lipid metabolic process)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016746"(acyltransferase activity)|go:"GO:0005618"(cell wall)|mint:O50440|refseq:NP_215700.1|refseq:WP_003406195.1|interpro:IPR013228(PE-PPE, C-terminal)	ensembl:ENSMUSG00000035354(gene)|ensembl:ENSMUST00000037968(transcript)|go:"GO:0000149"(SNARE binding)|go:"GO:0000323"(lytic vacuole)|go:"GO:0000421"(autophagosome membrane)|go:"GO:0000775"(chromosome, centromeric region)|go:"GO:0005764"(lysosome)|go:"GO:0005768"(endosome)|go:"GO:0005769"(early endosome)|go:"GO:0005770"(late endosome)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005813"(centrosome)|go:"GO:0006281"(DNA repair)|go:"GO:0006890"(retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum)|go:"GO:0006914"(autophagy)|go:"GO:0007051"(spindle organization)|go:"GO:0007059"(chromosome segregation)|go:"GO:0007098"(centrosome cycle)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0030496"(midbody)|go:"GO:0032465"(regulation of cytokinesis)|go:"GO:0032801"(receptor catabolic process)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035493"(SNARE complex assembly)|go:"GO:0045335"(phagocytic vesicle)|go:"GO:0046718"(viral entry into host cell)|go:"GO:0051684"(maintenance of Golgi location)|go:"GO:0070418"(DNA-dependent protein kinase complex)|go:"GO:0071900"(regulation of protein serine/threonine kinase activity)|go:"GO:0097352"(autophagosome maturation)|go:"GO:0097680"(double-strand break repair via classical nonhomologous end joining)|interpro:IPR000008(C2 calcium-dependent membrane targeting)|interpro:IPR018791|interpro:IPR035892|mint:Q8K245|rcsb pdb:5YR0|reactome:R-MMU-1632852|refseq:NP_848750.3	-	-	-	figure legend:ST5|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2020/07/08	2020/08/14	rogid:IXzYfb7UxFgqBXPZ6NZHLy3hdTc83332	rogid:rzFzOhdqb0elqRBuF+JOh7I3AsI10090	rigid:+V6QiNfppyvvlAGJHewvSn+f/Hw	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:I6YC03	uniprotkb:Q8K245	intact:EBI-25768074	intact:EBI-6678333|ensembl:ENSMUSP00000045297|intact:EBI-10689401|uniprotkb:Q8BVI8|uniprotkb:Q8C0K8	psi-mi:ephb_myctu(display_long)|uniprotkb:ephB(gene name)|psi-mi:ephB(display_short)|uniprotkb:Epoxide hydrolase EphB(gene name synonym)|uniprotkb:LH57_10545(orf name)|uniprotkb:Rv1938(locus name)	psi-mi:uvrag_mouse(display_long)|uniprotkb:Uvrag1(gene name synonym)|uniprotkb:Uvrag(gene name)|psi-mi:Uvrag(display_short)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2018)	doi:10.1093/nar/gkx1173|imex:IM-28235|pubmed:29165646	taxid:83332(myctu)|taxid:83332("Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)")	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0471"(MINT)	intact:EBI-25768814|imex:IM-28235-99	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	go:"GO:0009636"(response to toxic substance)|go:"GO:0016787"(hydrolase activity)|go:"GO:0018742"(epoxide hydrolase B activity)|go:"GO:0042803"(protein homodimerization activity)|mint:I6YC03|refseq:NP_216454.1|refseq:WP_003899091.1|interpro:IPR029058|interpro:IPR000073(Alpha/beta hydrolase fold-1)|interpro:IPR000639(Epoxide hydrolase-like)	ensembl:ENSMUSG00000035354(gene)|ensembl:ENSMUST00000037968(transcript)|go:"GO:0000149"(SNARE binding)|go:"GO:0000323"(lytic vacuole)|go:"GO:0000421"(autophagosome membrane)|go:"GO:0000775"(chromosome, centromeric region)|go:"GO:0005764"(lysosome)|go:"GO:0005768"(endosome)|go:"GO:0005769"(early endosome)|go:"GO:0005770"(late endosome)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005813"(centrosome)|go:"GO:0006281"(DNA repair)|go:"GO:0006890"(retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum)|go:"GO:0006914"(autophagy)|go:"GO:0007051"(spindle organization)|go:"GO:0007059"(chromosome segregation)|go:"GO:0007098"(centrosome cycle)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0030496"(midbody)|go:"GO:0032465"(regulation of cytokinesis)|go:"GO:0032801"(receptor catabolic process)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035493"(SNARE complex assembly)|go:"GO:0045335"(phagocytic vesicle)|go:"GO:0046718"(viral entry into host cell)|go:"GO:0051684"(maintenance of Golgi location)|go:"GO:0070418"(DNA-dependent protein kinase complex)|go:"GO:0071900"(regulation of protein serine/threonine kinase activity)|go:"GO:0097352"(autophagosome maturation)|go:"GO:0097680"(double-strand break repair via classical nonhomologous end joining)|interpro:IPR000008(C2 calcium-dependent membrane targeting)|interpro:IPR018791|interpro:IPR035892|mint:Q8K245|rcsb pdb:5YR0|reactome:R-MMU-1632852|refseq:NP_848750.3	-	-	-	figure legend:ST5|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2020/07/08	2020/08/14	rogid:sRxqN+k+jfx7zSE+ctNP+i+id0I83332	rogid:rzFzOhdqb0elqRBuF+JOh7I3AsI10090	rigid:8KPG63Lzk3i4oI6lNlqovpTm+08	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P9WHT9	uniprotkb:Q8K245	intact:EBI-7947958|uniprotkb:O33245|intact:MINT-7985947|uniprotkb:Q7D7I2|uniprotkb:L0T8V8	intact:EBI-6678333|ensembl:ENSMUSP00000045297|intact:EBI-10689401|uniprotkb:Q8BVI8|uniprotkb:Q8C0K8	psi-mi:psb_myctu(display_long)|uniprotkb:Proteasome core protein PrcB(gene name synonym)|uniprotkb:Rv2110c(locus name)|uniprotkb:prcB(gene name)|psi-mi:prcB(display_short)|uniprotkb:20S proteasome beta subunit(gene name synonym)	psi-mi:uvrag_mouse(display_long)|uniprotkb:Uvrag1(gene name synonym)|uniprotkb:Uvrag(gene name)|psi-mi:Uvrag(display_short)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2018)	doi:10.1093/nar/gkx1173|imex:IM-28235|pubmed:29165646	taxid:83332(myctu)|taxid:83332("Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)")	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0471"(MINT)	intact:EBI-25768808|imex:IM-28235-35	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	interpro:IPR029055|refseq:WP_003411023.1|interpro:IPR001353(20S proteasome, A and B subunits)|refseq:NP_216626.1|interpro:IPR023333|interpro:IPR022483|mint:P9WHT9|go:"GO:0004298"(threonine-type endopeptidase activity)|go:"GO:0005576"(extracellular region)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0010498"(proteasomal protein catabolic process)|go:"GO:0019773"(proteasome core complex, alpha-subunit complex)|go:"GO:0019774"(proteasome core complex, beta-subunit complex)|go:"GO:0019941"(modification-dependent protein catabolic process)|go:"GO:0030682"(mitigation of host defenses by symbiont)|go:"GO:0035375"(zymogen binding)|go:"GO:0051603"(proteolysis involved in cellular protein catabolic process)|rcsb pdb:2FHG|rcsb pdb:2FHH|rcsb pdb:2JAY|rcsb pdb:3H6F|rcsb pdb:3H6I|rcsb pdb:3HF9|rcsb pdb:3HFA|rcsb pdb:3KRD|rcsb pdb:3MFE|rcsb pdb:3MI0|rcsb pdb:3MKA|rcsb pdb:5LZP|rcsb pdb:5THO|rcsb pdb:5TRG|rcsb pdb:5TRR|rcsb pdb:5TRS|rcsb pdb:5TRY|rcsb pdb:5TS0|rcsb pdb:6BGL|rcsb pdb:6BGO|rcsb pdb:6OCW|rcsb pdb:6OCZ|rcsb pdb:6ODE	ensembl:ENSMUSG00000035354(gene)|ensembl:ENSMUST00000037968(transcript)|go:"GO:0000149"(SNARE binding)|go:"GO:0000323"(lytic vacuole)|go:"GO:0000421"(autophagosome membrane)|go:"GO:0000775"(chromosome, centromeric region)|go:"GO:0005764"(lysosome)|go:"GO:0005768"(endosome)|go:"GO:0005769"(early endosome)|go:"GO:0005770"(late endosome)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005813"(centrosome)|go:"GO:0006281"(DNA repair)|go:"GO:0006890"(retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum)|go:"GO:0006914"(autophagy)|go:"GO:0007051"(spindle organization)|go:"GO:0007059"(chromosome segregation)|go:"GO:0007098"(centrosome cycle)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0030496"(midbody)|go:"GO:0032465"(regulation of cytokinesis)|go:"GO:0032801"(receptor catabolic process)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035493"(SNARE complex assembly)|go:"GO:0045335"(phagocytic vesicle)|go:"GO:0046718"(viral entry into host cell)|go:"GO:0051684"(maintenance of Golgi location)|go:"GO:0070418"(DNA-dependent protein kinase complex)|go:"GO:0071900"(regulation of protein serine/threonine kinase activity)|go:"GO:0097352"(autophagosome maturation)|go:"GO:0097680"(double-strand break repair via classical nonhomologous end joining)|interpro:IPR000008(C2 calcium-dependent membrane targeting)|interpro:IPR018791|interpro:IPR035892|mint:Q8K245|rcsb pdb:5YR0|reactome:R-MMU-1632852|refseq:NP_848750.3	-	crc64:3FC3FCD81231E129|comment:mint	-	figure legend:ST5|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2020/07/08	2020/08/14	rogid:hQ8Eci/BIL/quaWNhklTdFRPHDI83332	rogid:rzFzOhdqb0elqRBuF+JOh7I3AsI10090	rigid:HQ5NTJLjeYDMxXoBET0RPeW2HBI	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:I6Y946	uniprotkb:Q8K245	intact:EBI-25767727	intact:EBI-6678333|ensembl:ENSMUSP00000045297|intact:EBI-10689401|uniprotkb:Q8BVI8|uniprotkb:Q8C0K8	psi-mi:i6y946_myctu(display_long)|uniprotkb:Rv0925c(locus name)	psi-mi:uvrag_mouse(display_long)|uniprotkb:Uvrag1(gene name synonym)|uniprotkb:Uvrag(gene name)|psi-mi:Uvrag(display_short)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2018)	doi:10.1093/nar/gkx1173|imex:IM-28235|pubmed:29165646	taxid:83332(myctu)|taxid:83332("Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)")	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0471"(MINT)	intact:EBI-25768802|imex:IM-28235-197	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	go:"GO:0016491"(oxidoreductase activity)|mint:I6Y946|refseq:NP_215440.1|refseq:WP_003404764.1|interpro:IPR029039|interpro:IPR005025(NADPH-dependent FMN reductase)	ensembl:ENSMUSG00000035354(gene)|ensembl:ENSMUST00000037968(transcript)|go:"GO:0000149"(SNARE binding)|go:"GO:0000323"(lytic vacuole)|go:"GO:0000421"(autophagosome membrane)|go:"GO:0000775"(chromosome, centromeric region)|go:"GO:0005764"(lysosome)|go:"GO:0005768"(endosome)|go:"GO:0005769"(early endosome)|go:"GO:0005770"(late endosome)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005813"(centrosome)|go:"GO:0006281"(DNA repair)|go:"GO:0006890"(retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum)|go:"GO:0006914"(autophagy)|go:"GO:0007051"(spindle organization)|go:"GO:0007059"(chromosome segregation)|go:"GO:0007098"(centrosome cycle)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0030496"(midbody)|go:"GO:0032465"(regulation of cytokinesis)|go:"GO:0032801"(receptor catabolic process)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035493"(SNARE complex assembly)|go:"GO:0045335"(phagocytic vesicle)|go:"GO:0046718"(viral entry into host cell)|go:"GO:0051684"(maintenance of Golgi location)|go:"GO:0070418"(DNA-dependent protein kinase complex)|go:"GO:0071900"(regulation of protein serine/threonine kinase activity)|go:"GO:0097352"(autophagosome maturation)|go:"GO:0097680"(double-strand break repair via classical nonhomologous end joining)|interpro:IPR000008(C2 calcium-dependent membrane targeting)|interpro:IPR018791|interpro:IPR035892|mint:Q8K245|rcsb pdb:5YR0|reactome:R-MMU-1632852|refseq:NP_848750.3	-	-	-	figure legend:ST5|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2020/07/08	2020/08/14	rogid:JOW06LtizimdrjJdMmMnM9ru8n083332	rogid:rzFzOhdqb0elqRBuF+JOh7I3AsI10090	rigid:CoGGZQfgjIK113ra6X1G4/bzc/I	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:O07422	uniprotkb:Q8K245	intact:EBI-25767563|uniprotkb:F2GLX6|uniprotkb:I6Y302|uniprotkb:Q7DAB9	intact:EBI-6678333|ensembl:ENSMUSP00000045297|intact:EBI-10689401|uniprotkb:Q8BVI8|uniprotkb:Q8C0K8	psi-mi:o07422_myctu(display_long)|uniprotkb:Rv0178(locus name)	psi-mi:uvrag_mouse(display_long)|uniprotkb:Uvrag1(gene name synonym)|uniprotkb:Uvrag(gene name)|psi-mi:Uvrag(display_short)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2018)	doi:10.1093/nar/gkx1173|imex:IM-28235|pubmed:29165646	taxid:83332(myctu)|taxid:83332("Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)")	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0471"(MINT)	intact:EBI-25768796|imex:IM-28235-297	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	go:"GO:0005576"(extracellular region)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0051701"(biological process involved in interaction with host)|mint:O07422|refseq:NP_214692.1|refseq:WP_003899844.1	ensembl:ENSMUSG00000035354(gene)|ensembl:ENSMUST00000037968(transcript)|go:"GO:0000149"(SNARE binding)|go:"GO:0000323"(lytic vacuole)|go:"GO:0000421"(autophagosome membrane)|go:"GO:0000775"(chromosome, centromeric region)|go:"GO:0005764"(lysosome)|go:"GO:0005768"(endosome)|go:"GO:0005769"(early endosome)|go:"GO:0005770"(late endosome)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005813"(centrosome)|go:"GO:0006281"(DNA repair)|go:"GO:0006890"(retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum)|go:"GO:0006914"(autophagy)|go:"GO:0007051"(spindle organization)|go:"GO:0007059"(chromosome segregation)|go:"GO:0007098"(centrosome cycle)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0030496"(midbody)|go:"GO:0032465"(regulation of cytokinesis)|go:"GO:0032801"(receptor catabolic process)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035493"(SNARE complex assembly)|go:"GO:0045335"(phagocytic vesicle)|go:"GO:0046718"(viral entry into host cell)|go:"GO:0051684"(maintenance of Golgi location)|go:"GO:0070418"(DNA-dependent protein kinase complex)|go:"GO:0071900"(regulation of protein serine/threonine kinase activity)|go:"GO:0097352"(autophagosome maturation)|go:"GO:0097680"(double-strand break repair via classical nonhomologous end joining)|interpro:IPR000008(C2 calcium-dependent membrane targeting)|interpro:IPR018791|interpro:IPR035892|mint:Q8K245|rcsb pdb:5YR0|reactome:R-MMU-1632852|refseq:NP_848750.3	-	-	-	figure legend:ST5|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2020/07/08	2020/08/14	rogid:lGOg72Osvz8819m674JzGUcHEj483332	rogid:rzFzOhdqb0elqRBuF+JOh7I3AsI10090	rigid:Cri3NKIDNyxt2dq9x697ci1X87o	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P9WJB9	uniprotkb:Q8K245	intact:EBI-25767670|uniprotkb:L0TE21|uniprotkb:O69744|uniprotkb:Q7D4P0	intact:EBI-6678333|ensembl:ENSMUSP00000045297|intact:EBI-10689401|uniprotkb:Q8BVI8|uniprotkb:Q8C0K8	psi-mi:espl_myctu(display_long)|uniprotkb:espL(gene name)|psi-mi:espL(display_short)|uniprotkb:Rv3880c(locus name)	psi-mi:uvrag_mouse(display_long)|uniprotkb:Uvrag1(gene name synonym)|uniprotkb:Uvrag(gene name)|psi-mi:Uvrag(display_short)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2018)	doi:10.1093/nar/gkx1173|imex:IM-28235|pubmed:29165646	taxid:83332(myctu)|taxid:83332("Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)")	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0471"(MINT)	intact:EBI-25768790|imex:IM-28235-195	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	go:"GO:0003677"(DNA binding)|go:"GO:0005618"(cell wall)|go:"GO:0005886"(plasma membrane)|go:"GO:0052170"(suppression by symbiont of host innate immune response)|mint:P9WJB9|refseq:NP_218397.1|refseq:WP_003399988.1|interpro:IPR036894|interpro:IPR004401(Conserved hypothetical protein CHP00103)	ensembl:ENSMUSG00000035354(gene)|ensembl:ENSMUST00000037968(transcript)|go:"GO:0000149"(SNARE binding)|go:"GO:0000323"(lytic vacuole)|go:"GO:0000421"(autophagosome membrane)|go:"GO:0000775"(chromosome, centromeric region)|go:"GO:0005764"(lysosome)|go:"GO:0005768"(endosome)|go:"GO:0005769"(early endosome)|go:"GO:0005770"(late endosome)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005813"(centrosome)|go:"GO:0006281"(DNA repair)|go:"GO:0006890"(retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum)|go:"GO:0006914"(autophagy)|go:"GO:0007051"(spindle organization)|go:"GO:0007059"(chromosome segregation)|go:"GO:0007098"(centrosome cycle)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0030496"(midbody)|go:"GO:0032465"(regulation of cytokinesis)|go:"GO:0032801"(receptor catabolic process)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035493"(SNARE complex assembly)|go:"GO:0045335"(phagocytic vesicle)|go:"GO:0046718"(viral entry into host cell)|go:"GO:0051684"(maintenance of Golgi location)|go:"GO:0070418"(DNA-dependent protein kinase complex)|go:"GO:0071900"(regulation of protein serine/threonine kinase activity)|go:"GO:0097352"(autophagosome maturation)|go:"GO:0097680"(double-strand break repair via classical nonhomologous end joining)|interpro:IPR000008(C2 calcium-dependent membrane targeting)|interpro:IPR018791|interpro:IPR035892|mint:Q8K245|rcsb pdb:5YR0|reactome:R-MMU-1632852|refseq:NP_848750.3	-	-	-	figure legend:ST5|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2020/07/08	2020/08/14	rogid:BspTx2RZuhJaQ319NBDIyOreqfE83332	rogid:rzFzOhdqb0elqRBuF+JOh7I3AsI10090	rigid:CKBRyww/Jix9y56P8EsB3IXCzME	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q8K245	uniprotkb:P9WNI7	intact:EBI-6678333|ensembl:ENSMUSP00000045297|intact:EBI-10689401|uniprotkb:Q8BVI8|uniprotkb:Q8C0K8	intact:EBI-9027314|uniprotkb:P95242|uniprotkb:L0T9C9	psi-mi:uvrag_mouse(display_long)|uniprotkb:Uvrag1(gene name synonym)|uniprotkb:Uvrag(gene name)|psi-mi:Uvrag(display_short)	psi-mi:esxo_myctu(display_long)|uniprotkb:esxO(gene name)|psi-mi:esxO(display_short)|uniprotkb:MTCY98.15c(orf name)|uniprotkb:Rv2346c(locus name)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2018)	doi:10.1093/nar/gkx1173|imex:IM-28235|pubmed:29165646	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:83332(myctu)|taxid:83332("Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)")	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0471"(MINT)	intact:EBI-25768784|imex:IM-28235-33	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSMUSG00000035354(gene)|ensembl:ENSMUST00000037968(transcript)|go:"GO:0000149"(SNARE binding)|go:"GO:0000323"(lytic vacuole)|go:"GO:0000421"(autophagosome membrane)|go:"GO:0000775"(chromosome, centromeric region)|go:"GO:0005764"(lysosome)|go:"GO:0005768"(endosome)|go:"GO:0005769"(early endosome)|go:"GO:0005770"(late endosome)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005813"(centrosome)|go:"GO:0006281"(DNA repair)|go:"GO:0006890"(retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum)|go:"GO:0006914"(autophagy)|go:"GO:0007051"(spindle organization)|go:"GO:0007059"(chromosome segregation)|go:"GO:0007098"(centrosome cycle)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0030496"(midbody)|go:"GO:0032465"(regulation of cytokinesis)|go:"GO:0032801"(receptor catabolic process)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035493"(SNARE complex assembly)|go:"GO:0045335"(phagocytic vesicle)|go:"GO:0046718"(viral entry into host cell)|go:"GO:0051684"(maintenance of Golgi location)|go:"GO:0070418"(DNA-dependent protein kinase complex)|go:"GO:0071900"(regulation of protein serine/threonine kinase activity)|go:"GO:0097352"(autophagosome maturation)|go:"GO:0097680"(double-strand break repair via classical nonhomologous end joining)|interpro:IPR000008(C2 calcium-dependent membrane targeting)|interpro:IPR018791|interpro:IPR035892|mint:Q8K245|rcsb pdb:5YR0|reactome:R-MMU-1632852|refseq:NP_848750.3	mint:P9WNI7|interpro:IPR036689|interpro:IPR009416(Protein of unknown function DUF1066)|interpro:IPR010310(Protein of unknown function DUF909)|refseq:NP_216862.1|refseq:WP_003899283.1|go:"GO:0005576"(extracellular region)|go:"GO:0005618"(cell wall)|go:"GO:0005886"(plasma membrane)|rcsb pdb:3OGI|rcsb pdb:4GZR	-	-	-	figure legend:ST5|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2020/07/08	2020/08/14	rogid:rzFzOhdqb0elqRBuF+JOh7I3AsI10090	rogid:jYoNmHY+G6+S39CX1qRFCxjy0xw83332	rigid:A0zcbmKWkI0uq4XRO/z34ZU99r4	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P9WIT1	uniprotkb:Q8K245	intact:EBI-25767539|uniprotkb:L0TBU2|uniprotkb:Q50685|uniprotkb:Q7D7C5	intact:EBI-6678333|ensembl:ENSMUSP00000045297|intact:EBI-10689401|uniprotkb:Q8BVI8|uniprotkb:Q8C0K8	psi-mi:y2280_myctu(display_long)|uniprotkb:Rv2280(locus name)	psi-mi:uvrag_mouse(display_long)|uniprotkb:Uvrag1(gene name synonym)|uniprotkb:Uvrag(gene name)|psi-mi:Uvrag(display_short)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2018)	doi:10.1093/nar/gkx1173|imex:IM-28235|pubmed:29165646	taxid:83332(myctu)|taxid:83332("Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)")	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0471"(MINT)	intact:EBI-25768778|imex:IM-28235-215	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	go:"GO:0005618"(cell wall)|go:"GO:0005886"(plasma membrane)|go:"GO:0016491"(oxidoreductase activity)|go:"GO:0071949"(FAD binding)|interpro:IPR016169(CO dehydrogenase flavoprotein-like, FAD-binding, subdomain 2)|mint:P9WIT1|refseq:WP_003411690.1|interpro:IPR016166(FAD-binding, type 2)|interpro:IPR036318|interpro:IPR016164(FAD-linked oxidase-like, C-terminal)|interpro:IPR004113(FAD-linked oxidase, C-terminal)|interpro:IPR006094(FAD linked oxidase, N-terminal)|interpro:IPR016171(Vanillyl-alcohol oxidase, C-terminal subdomain 2)	ensembl:ENSMUSG00000035354(gene)|ensembl:ENSMUST00000037968(transcript)|go:"GO:0000149"(SNARE binding)|go:"GO:0000323"(lytic vacuole)|go:"GO:0000421"(autophagosome membrane)|go:"GO:0000775"(chromosome, centromeric region)|go:"GO:0005764"(lysosome)|go:"GO:0005768"(endosome)|go:"GO:0005769"(early endosome)|go:"GO:0005770"(late endosome)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005813"(centrosome)|go:"GO:0006281"(DNA repair)|go:"GO:0006890"(retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum)|go:"GO:0006914"(autophagy)|go:"GO:0007051"(spindle organization)|go:"GO:0007059"(chromosome segregation)|go:"GO:0007098"(centrosome cycle)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0030496"(midbody)|go:"GO:0032465"(regulation of cytokinesis)|go:"GO:0032801"(receptor catabolic process)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035493"(SNARE complex assembly)|go:"GO:0045335"(phagocytic vesicle)|go:"GO:0046718"(viral entry into host cell)|go:"GO:0051684"(maintenance of Golgi location)|go:"GO:0070418"(DNA-dependent protein kinase complex)|go:"GO:0071900"(regulation of protein serine/threonine kinase activity)|go:"GO:0097352"(autophagosome maturation)|go:"GO:0097680"(double-strand break repair via classical nonhomologous end joining)|interpro:IPR000008(C2 calcium-dependent membrane targeting)|interpro:IPR018791|interpro:IPR035892|mint:Q8K245|rcsb pdb:5YR0|reactome:R-MMU-1632852|refseq:NP_848750.3	-	-	-	figure legend:ST5|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2020/07/08	2020/08/14	rogid:TvFI3uuw9zREl1q0DeWIsHmCSEk83332	rogid:rzFzOhdqb0elqRBuF+JOh7I3AsI10090	rigid:LCXLnRRcYjZRSb1O3Bf9gWBOLig	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P9WN37	uniprotkb:Q8K245	intact:EBI-25767601|uniprotkb:L0T968|uniprotkb:P64245|uniprotkb:Q10378	intact:EBI-6678333|ensembl:ENSMUSP00000045297|intact:EBI-10689401|uniprotkb:Q8BVI8|uniprotkb:Q8C0K8	psi-mi:gln1a_myctu(display_long)|uniprotkb:glnA2(gene name)|psi-mi:glnA2(display_short)|uniprotkb:Glutamate--ammonia ligase(gene name synonym)|uniprotkb:Glutamine synthetase I alpha(gene name synonym)|uniprotkb:MTCY190.33c(orf name)|uniprotkb:MTCY427.03c(orf name)|uniprotkb:Rv2222c(locus name)	psi-mi:uvrag_mouse(display_long)|uniprotkb:Uvrag1(gene name synonym)|uniprotkb:Uvrag(gene name)|psi-mi:Uvrag(display_short)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2018)	doi:10.1093/nar/gkx1173|imex:IM-28235|pubmed:29165646	taxid:83332(myctu)|taxid:83332("Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)")	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0471"(MINT)	intact:EBI-25768772|imex:IM-28235-179	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	go:"GO:0004356"(glutamate-ammonia ligase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0006542"(glutamine biosynthetic process)|go:"GO:0046872"(metal ion binding)|go:"GO:0050001"(D-glutaminase activity)|mint:P9WN37|refseq:NP_216738.1|refseq:WP_003411482.1|interpro:IPR008147(Glutamine synthetase, beta-Grasp)|interpro:IPR036651|interpro:IPR014746(Glutamine synthetase/guanido kinase, catalytic region)|interpro:IPR008146(Glutamine synthetase, catalytic region)|interpro:IPR027303	ensembl:ENSMUSG00000035354(gene)|ensembl:ENSMUST00000037968(transcript)|go:"GO:0000149"(SNARE binding)|go:"GO:0000323"(lytic vacuole)|go:"GO:0000421"(autophagosome membrane)|go:"GO:0000775"(chromosome, centromeric region)|go:"GO:0005764"(lysosome)|go:"GO:0005768"(endosome)|go:"GO:0005769"(early endosome)|go:"GO:0005770"(late endosome)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005813"(centrosome)|go:"GO:0006281"(DNA repair)|go:"GO:0006890"(retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum)|go:"GO:0006914"(autophagy)|go:"GO:0007051"(spindle organization)|go:"GO:0007059"(chromosome segregation)|go:"GO:0007098"(centrosome cycle)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0030496"(midbody)|go:"GO:0032465"(regulation of cytokinesis)|go:"GO:0032801"(receptor catabolic process)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035493"(SNARE complex assembly)|go:"GO:0045335"(phagocytic vesicle)|go:"GO:0046718"(viral entry into host cell)|go:"GO:0051684"(maintenance of Golgi location)|go:"GO:0070418"(DNA-dependent protein kinase complex)|go:"GO:0071900"(regulation of protein serine/threonine kinase activity)|go:"GO:0097352"(autophagosome maturation)|go:"GO:0097680"(double-strand break repair via classical nonhomologous end joining)|interpro:IPR000008(C2 calcium-dependent membrane targeting)|interpro:IPR018791|interpro:IPR035892|mint:Q8K245|rcsb pdb:5YR0|reactome:R-MMU-1632852|refseq:NP_848750.3	-	-	-	figure legend:ST5|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2020/07/08	2020/08/14	rogid:LDIpolmw5yhv2iG5+8HKbWlwT8883332	rogid:rzFzOhdqb0elqRBuF+JOh7I3AsI10090	rigid:QNRGw/1Wx1plP1UgBopwMlEonng	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P9WHV1	uniprotkb:P70315	intact:EBI-25768182|uniprotkb:L0TB68|uniprotkb:P65788|uniprotkb:P71921	intact:EBI-644195|ensembl:ENSMUSP00000033505	psi-mi:proa_myctu(display_long)|uniprotkb:proA(gene name)|psi-mi:proA(display_short)|uniprotkb:Glutamate-5-semialdehyde dehydrogenase(gene name synonym)|uniprotkb:Glutamyl-gamma-semialdehyde dehydrogenase(gene name synonym)|uniprotkb:MTCY428.20(orf name)|uniprotkb:Rv2427c(locus name)	psi-mi:wasp_mouse(display_long)|uniprotkb:Was(gene name)|psi-mi:Was(display_short)|uniprotkb:Wasp(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2018)	doi:10.1093/nar/gkx1173|imex:IM-28235|pubmed:29165646	taxid:83332(myctu)|taxid:83332("Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)")	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0471"(MINT)	intact:EBI-25768910|imex:IM-28235-347	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	go:"GO:0004350"(glutamate-5-semialdehyde dehydrogenase activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0050661"(NADP binding)|go:"GO:0055129"(L-proline biosynthetic process)|go:"GO:0005829"(cytosol)|mint:P9WHV1|refseq:NP_216943.1|refseq:WP_003412516.1|interpro:IPR016161(Aldehyde/histidinol dehydrogenase)|interpro:IPR016163(Aldehyde dehydrogenase, C-terminal)|interpro:IPR016162(Aldehyde dehydrogenase, N-terminal)|interpro:IPR015590(Aldehyde dehydrogenase)|interpro:IPR020593|interpro:IPR012134(Glutamate-5-semialdehyde dehydrogenase)|interpro:IPR000965(Gamma-glutamyl phosphate reductase GPR)	refseq:NP_033541.1|ensembl:ENSMUSG00000031165(gene)|ensembl:ENSMUST00000033505(transcript)|go:"GO:0002625"(regulation of T cell antigen processing and presentation)|go:"GO:0003779"(actin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0005884"(actin filament)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0006955"(immune response)|go:"GO:0008064"(regulation of actin polymerization or depolymerization)|go:"GO:0008154"(actin polymerization or depolymerization)|go:"GO:0010591"(regulation of lamellipodium assembly)|go:"GO:0012506"(vesicle membrane)|go:"GO:0016197"(endosomal transport)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030041"(actin filament polymerization)|go:"GO:0030048"(actin filament-based movement)|go:"GO:0031267"(small GTPase binding)|go:"GO:0032488"(Cdc42 protein signal transduction)|go:"GO:0035861"(site of double-strand break)|go:"GO:0042110"(T cell activation)|go:"GO:0042802"(identical protein binding)|go:"GO:0043274"(phospholipase binding)|go:"GO:0045335"(phagocytic vesicle)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0051492"(regulation of stress fiber assembly)|go:"GO:0051497"(negative regulation of stress fiber assembly)|go:"GO:0071346"(cellular response to interferon-gamma)|go:"GO:1905168"(positive regulation of double-strand break repair via homologous recombination)|go:"GO:2000146"(negative regulation of cell motility)|go:"GO:2000601"(positive regulation of Arp2/3 complex-mediated actin nucleation)|interpro:IPR000095(PAK-box/P21-Rho-binding)|interpro:IPR000697(EVH1)|interpro:IPR003124(Actin-binding WH2)|interpro:IPR011026(Wiscott-Aldrich syndrome, C-terminal)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR027641|interpro:IPR033927|interpro:IPR036936|mint:P70315|dip:DIP-36426N	-	-	-	figure legend:ST5|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2020/07/08	2020/08/14	rogid:fzCkUX2wrGj0ZK0LOaeT+UNWpwI83332	rogid:HbZjGXPVByZsiabjyX43YwKnJeA10090	rigid:ag13eVPbZjFLnDH4XYO2qToSAr8	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:O53319	uniprotkb:P70315	intact:EBI-25767766|uniprotkb:I6X6K2|uniprotkb:L0TEH7	intact:EBI-644195|ensembl:ENSMUSP00000033505	psi-mi:o53319_myctu(display_long)|uniprotkb:Rv3169(locus name)	psi-mi:wasp_mouse(display_long)|uniprotkb:Was(gene name)|psi-mi:Was(display_short)|uniprotkb:Wasp(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2018)	doi:10.1093/nar/gkx1173|imex:IM-28235|pubmed:29165646	taxid:83332(myctu)|taxid:83332("Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)")	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0471"(MINT)	intact:EBI-25768904|imex:IM-28235-199	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	go:"GO:0005886"(plasma membrane)|mint:O53319|refseq:NP_217685.1|refseq:WP_003416605.1	refseq:NP_033541.1|ensembl:ENSMUSG00000031165(gene)|ensembl:ENSMUST00000033505(transcript)|go:"GO:0002625"(regulation of T cell antigen processing and presentation)|go:"GO:0003779"(actin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0005884"(actin filament)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0006955"(immune response)|go:"GO:0008064"(regulation of actin polymerization or depolymerization)|go:"GO:0008154"(actin polymerization or depolymerization)|go:"GO:0010591"(regulation of lamellipodium assembly)|go:"GO:0012506"(vesicle membrane)|go:"GO:0016197"(endosomal transport)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030041"(actin filament polymerization)|go:"GO:0030048"(actin filament-based movement)|go:"GO:0031267"(small GTPase binding)|go:"GO:0032488"(Cdc42 protein signal transduction)|go:"GO:0035861"(site of double-strand break)|go:"GO:0042110"(T cell activation)|go:"GO:0042802"(identical protein binding)|go:"GO:0043274"(phospholipase binding)|go:"GO:0045335"(phagocytic vesicle)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0051492"(regulation of stress fiber assembly)|go:"GO:0051497"(negative regulation of stress fiber assembly)|go:"GO:0071346"(cellular response to interferon-gamma)|go:"GO:1905168"(positive regulation of double-strand break repair via homologous recombination)|go:"GO:2000146"(negative regulation of cell motility)|go:"GO:2000601"(positive regulation of Arp2/3 complex-mediated actin nucleation)|interpro:IPR000095(PAK-box/P21-Rho-binding)|interpro:IPR000697(EVH1)|interpro:IPR003124(Actin-binding WH2)|interpro:IPR011026(Wiscott-Aldrich syndrome, C-terminal)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR027641|interpro:IPR033927|interpro:IPR036936|mint:P70315|dip:DIP-36426N	-	-	-	figure legend:ST5|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2020/07/08	2020/08/14	rogid:Gd1O5B5qTAQflXzn9MR+6fgqvDs83332	rogid:HbZjGXPVByZsiabjyX43YwKnJeA10090	rigid:upK21O7Z6pUIB/lNoLcbcfTFcVY	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:O50440	uniprotkb:P70315	intact:EBI-25767742|uniprotkb:I6XXB2|uniprotkb:L0T7J5	intact:EBI-644195|ensembl:ENSMUSP00000033505	psi-mi:chp2_myctu(display_long)|uniprotkb:chp2(gene name)|psi-mi:chp2(display_short)|uniprotkb:LH57_06500(orf name)|uniprotkb:P425_01234(orf name)|uniprotkb:Rv1184c(locus name)|uniprotkb:RVBD_1184c(locus name)	psi-mi:wasp_mouse(display_long)|uniprotkb:Was(gene name)|psi-mi:Was(display_short)|uniprotkb:Wasp(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2018)	doi:10.1093/nar/gkx1173|imex:IM-28235|pubmed:29165646	taxid:83332(myctu)|taxid:83332("Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)")	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0471"(MINT)	intact:EBI-25768898|imex:IM-28235-119	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	go:"GO:0005886"(plasma membrane)|go:"GO:0006629"(lipid metabolic process)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016746"(acyltransferase activity)|go:"GO:0005618"(cell wall)|mint:O50440|refseq:NP_215700.1|refseq:WP_003406195.1|interpro:IPR013228(PE-PPE, C-terminal)	refseq:NP_033541.1|ensembl:ENSMUSG00000031165(gene)|ensembl:ENSMUST00000033505(transcript)|go:"GO:0002625"(regulation of T cell antigen processing and presentation)|go:"GO:0003779"(actin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0005884"(actin filament)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0006955"(immune response)|go:"GO:0008064"(regulation of actin polymerization or depolymerization)|go:"GO:0008154"(actin polymerization or depolymerization)|go:"GO:0010591"(regulation of lamellipodium assembly)|go:"GO:0012506"(vesicle membrane)|go:"GO:0016197"(endosomal transport)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030041"(actin filament polymerization)|go:"GO:0030048"(actin filament-based movement)|go:"GO:0031267"(small GTPase binding)|go:"GO:0032488"(Cdc42 protein signal transduction)|go:"GO:0035861"(site of double-strand break)|go:"GO:0042110"(T cell activation)|go:"GO:0042802"(identical protein binding)|go:"GO:0043274"(phospholipase binding)|go:"GO:0045335"(phagocytic vesicle)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0051492"(regulation of stress fiber assembly)|go:"GO:0051497"(negative regulation of stress fiber assembly)|go:"GO:0071346"(cellular response to interferon-gamma)|go:"GO:1905168"(positive regulation of double-strand break repair via homologous recombination)|go:"GO:2000146"(negative regulation of cell motility)|go:"GO:2000601"(positive regulation of Arp2/3 complex-mediated actin nucleation)|interpro:IPR000095(PAK-box/P21-Rho-binding)|interpro:IPR000697(EVH1)|interpro:IPR003124(Actin-binding WH2)|interpro:IPR011026(Wiscott-Aldrich syndrome, C-terminal)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR027641|interpro:IPR033927|interpro:IPR036936|mint:P70315|dip:DIP-36426N	-	-	-	figure legend:ST5|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2020/07/08	2020/08/14	rogid:IXzYfb7UxFgqBXPZ6NZHLy3hdTc83332	rogid:HbZjGXPVByZsiabjyX43YwKnJeA10090	rigid:KUgOJ5+9buUH/cCYT5vtW2fujWk	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:I6YC03	uniprotkb:P70315	intact:EBI-25768074	intact:EBI-644195|ensembl:ENSMUSP00000033505	psi-mi:ephb_myctu(display_long)|uniprotkb:ephB(gene name)|psi-mi:ephB(display_short)|uniprotkb:Epoxide hydrolase EphB(gene name synonym)|uniprotkb:LH57_10545(orf name)|uniprotkb:Rv1938(locus name)	psi-mi:wasp_mouse(display_long)|uniprotkb:Was(gene name)|psi-mi:Was(display_short)|uniprotkb:Wasp(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2018)	doi:10.1093/nar/gkx1173|imex:IM-28235|pubmed:29165646	taxid:83332(myctu)|taxid:83332("Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)")	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0471"(MINT)	intact:EBI-25768892|imex:IM-28235-117	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	go:"GO:0009636"(response to toxic substance)|go:"GO:0016787"(hydrolase activity)|go:"GO:0018742"(epoxide hydrolase B activity)|go:"GO:0042803"(protein homodimerization activity)|mint:I6YC03|refseq:NP_216454.1|refseq:WP_003899091.1|interpro:IPR029058|interpro:IPR000073(Alpha/beta hydrolase fold-1)|interpro:IPR000639(Epoxide hydrolase-like)	refseq:NP_033541.1|ensembl:ENSMUSG00000031165(gene)|ensembl:ENSMUST00000033505(transcript)|go:"GO:0002625"(regulation of T cell antigen processing and presentation)|go:"GO:0003779"(actin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0005884"(actin filament)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0006955"(immune response)|go:"GO:0008064"(regulation of actin polymerization or depolymerization)|go:"GO:0008154"(actin polymerization or depolymerization)|go:"GO:0010591"(regulation of lamellipodium assembly)|go:"GO:0012506"(vesicle membrane)|go:"GO:0016197"(endosomal transport)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030041"(actin filament polymerization)|go:"GO:0030048"(actin filament-based movement)|go:"GO:0031267"(small GTPase binding)|go:"GO:0032488"(Cdc42 protein signal transduction)|go:"GO:0035861"(site of double-strand break)|go:"GO:0042110"(T cell activation)|go:"GO:0042802"(identical protein binding)|go:"GO:0043274"(phospholipase binding)|go:"GO:0045335"(phagocytic vesicle)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0051492"(regulation of stress fiber assembly)|go:"GO:0051497"(negative regulation of stress fiber assembly)|go:"GO:0071346"(cellular response to interferon-gamma)|go:"GO:1905168"(positive regulation of double-strand break repair via homologous recombination)|go:"GO:2000146"(negative regulation of cell motility)|go:"GO:2000601"(positive regulation of Arp2/3 complex-mediated actin nucleation)|interpro:IPR000095(PAK-box/P21-Rho-binding)|interpro:IPR000697(EVH1)|interpro:IPR003124(Actin-binding WH2)|interpro:IPR011026(Wiscott-Aldrich syndrome, C-terminal)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR027641|interpro:IPR033927|interpro:IPR036936|mint:P70315|dip:DIP-36426N	-	-	-	figure legend:ST5|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2020/07/08	2020/08/14	rogid:sRxqN+k+jfx7zSE+ctNP+i+id0I83332	rogid:HbZjGXPVByZsiabjyX43YwKnJeA10090	rigid:rVn7PhvSxgQxcsGtqo2TKJGZc74	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:O53850	uniprotkb:P70315	intact:EBI-25768148|uniprotkb:F2GJ15|uniprotkb:I6XWE0	intact:EBI-644195|ensembl:ENSMUSP00000033505	psi-mi:o53850_myctu(display_long)|uniprotkb:lpqR(gene name)|psi-mi:lpqR(display_short)|uniprotkb:Rv0838(locus name)	psi-mi:wasp_mouse(display_long)|uniprotkb:Was(gene name)|psi-mi:Was(display_short)|uniprotkb:Wasp(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2018)	doi:10.1093/nar/gkx1173|imex:IM-28235|pubmed:29165646	taxid:83332(myctu)|taxid:83332("Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)")	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0471"(MINT)	intact:EBI-25768886|imex:IM-28235-345	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	go:"GO:0005576"(extracellular region)|go:"GO:0008237"(metallopeptidase activity)|go:"GO:0008270"(zinc ion binding)|go:"GO:0016805"(dipeptidase activity)|go:"GO:0071555"(cell wall organization)|mint:O53850|refseq:NP_215353.1|refseq:WP_003898609.1|interpro:IPR000755(Peptidase M15D, vanX D-ala-D-ala dipeptidase)|interpro:IPR009045(Hedgehog/DD-peptidase, zinc-binding motif)	refseq:NP_033541.1|ensembl:ENSMUSG00000031165(gene)|ensembl:ENSMUST00000033505(transcript)|go:"GO:0002625"(regulation of T cell antigen processing and presentation)|go:"GO:0003779"(actin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0005884"(actin filament)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0006955"(immune response)|go:"GO:0008064"(regulation of actin polymerization or depolymerization)|go:"GO:0008154"(actin polymerization or depolymerization)|go:"GO:0010591"(regulation of lamellipodium assembly)|go:"GO:0012506"(vesicle membrane)|go:"GO:0016197"(endosomal transport)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030041"(actin filament polymerization)|go:"GO:0030048"(actin filament-based movement)|go:"GO:0031267"(small GTPase binding)|go:"GO:0032488"(Cdc42 protein signal transduction)|go:"GO:0035861"(site of double-strand break)|go:"GO:0042110"(T cell activation)|go:"GO:0042802"(identical protein binding)|go:"GO:0043274"(phospholipase binding)|go:"GO:0045335"(phagocytic vesicle)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0051492"(regulation of stress fiber assembly)|go:"GO:0051497"(negative regulation of stress fiber assembly)|go:"GO:0071346"(cellular response to interferon-gamma)|go:"GO:1905168"(positive regulation of double-strand break repair via homologous recombination)|go:"GO:2000146"(negative regulation of cell motility)|go:"GO:2000601"(positive regulation of Arp2/3 complex-mediated actin nucleation)|interpro:IPR000095(PAK-box/P21-Rho-binding)|interpro:IPR000697(EVH1)|interpro:IPR003124(Actin-binding WH2)|interpro:IPR011026(Wiscott-Aldrich syndrome, C-terminal)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR027641|interpro:IPR033927|interpro:IPR036936|mint:P70315|dip:DIP-36426N	-	-	-	figure legend:ST5|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2020/07/08	2020/08/14	rogid:40KIrYcfAW5IBFq1Hx5FLVOcLf483332	rogid:HbZjGXPVByZsiabjyX43YwKnJeA10090	rigid:+XHoUkqueneAu9GyyIWcQwUhlz8	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:I6Y946	uniprotkb:P70315	intact:EBI-25767727	intact:EBI-644195|ensembl:ENSMUSP00000033505	psi-mi:i6y946_myctu(display_long)|uniprotkb:Rv0925c(locus name)	psi-mi:wasp_mouse(display_long)|uniprotkb:Was(gene name)|psi-mi:Was(display_short)|uniprotkb:Wasp(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2018)	doi:10.1093/nar/gkx1173|imex:IM-28235|pubmed:29165646	taxid:83332(myctu)|taxid:83332("Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)")	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0471"(MINT)	intact:EBI-25768880|imex:IM-28235-279	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	go:"GO:0016491"(oxidoreductase activity)|mint:I6Y946|refseq:NP_215440.1|refseq:WP_003404764.1|interpro:IPR029039|interpro:IPR005025(NADPH-dependent FMN reductase)	refseq:NP_033541.1|ensembl:ENSMUSG00000031165(gene)|ensembl:ENSMUST00000033505(transcript)|go:"GO:0002625"(regulation of T cell antigen processing and presentation)|go:"GO:0003779"(actin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0005884"(actin filament)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0006955"(immune response)|go:"GO:0008064"(regulation of actin polymerization or depolymerization)|go:"GO:0008154"(actin polymerization or depolymerization)|go:"GO:0010591"(regulation of lamellipodium assembly)|go:"GO:0012506"(vesicle membrane)|go:"GO:0016197"(endosomal transport)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030041"(actin filament polymerization)|go:"GO:0030048"(actin filament-based movement)|go:"GO:0031267"(small GTPase binding)|go:"GO:0032488"(Cdc42 protein signal transduction)|go:"GO:0035861"(site of double-strand break)|go:"GO:0042110"(T cell activation)|go:"GO:0042802"(identical protein binding)|go:"GO:0043274"(phospholipase binding)|go:"GO:0045335"(phagocytic vesicle)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0051492"(regulation of stress fiber assembly)|go:"GO:0051497"(negative regulation of stress fiber assembly)|go:"GO:0071346"(cellular response to interferon-gamma)|go:"GO:1905168"(positive regulation of double-strand break repair via homologous recombination)|go:"GO:2000146"(negative regulation of cell motility)|go:"GO:2000601"(positive regulation of Arp2/3 complex-mediated actin nucleation)|interpro:IPR000095(PAK-box/P21-Rho-binding)|interpro:IPR000697(EVH1)|interpro:IPR003124(Actin-binding WH2)|interpro:IPR011026(Wiscott-Aldrich syndrome, C-terminal)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR027641|interpro:IPR033927|interpro:IPR036936|mint:P70315|dip:DIP-36426N	-	-	-	figure legend:ST5|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2020/07/08	2020/08/14	rogid:JOW06LtizimdrjJdMmMnM9ru8n083332	rogid:HbZjGXPVByZsiabjyX43YwKnJeA10090	rigid:6Yu4uSPndSUFgYH/utKhjtSQVEI	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:O07422	uniprotkb:P70315	intact:EBI-25767563|uniprotkb:F2GLX6|uniprotkb:I6Y302|uniprotkb:Q7DAB9	intact:EBI-644195|ensembl:ENSMUSP00000033505	psi-mi:o07422_myctu(display_long)|uniprotkb:Rv0178(locus name)	psi-mi:wasp_mouse(display_long)|uniprotkb:Was(gene name)|psi-mi:Was(display_short)|uniprotkb:Wasp(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2018)	doi:10.1093/nar/gkx1173|imex:IM-28235|pubmed:29165646	taxid:83332(myctu)|taxid:83332("Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)")	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0471"(MINT)	intact:EBI-25768874|imex:IM-28235-343	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	go:"GO:0005576"(extracellular region)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0051701"(biological process involved in interaction with host)|mint:O07422|refseq:NP_214692.1|refseq:WP_003899844.1	refseq:NP_033541.1|ensembl:ENSMUSG00000031165(gene)|ensembl:ENSMUST00000033505(transcript)|go:"GO:0002625"(regulation of T cell antigen processing and presentation)|go:"GO:0003779"(actin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0005884"(actin filament)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0006955"(immune response)|go:"GO:0008064"(regulation of actin polymerization or depolymerization)|go:"GO:0008154"(actin polymerization or depolymerization)|go:"GO:0010591"(regulation of lamellipodium assembly)|go:"GO:0012506"(vesicle membrane)|go:"GO:0016197"(endosomal transport)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030041"(actin filament polymerization)|go:"GO:0030048"(actin filament-based movement)|go:"GO:0031267"(small GTPase binding)|go:"GO:0032488"(Cdc42 protein signal transduction)|go:"GO:0035861"(site of double-strand break)|go:"GO:0042110"(T cell activation)|go:"GO:0042802"(identical protein binding)|go:"GO:0043274"(phospholipase binding)|go:"GO:0045335"(phagocytic vesicle)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0051492"(regulation of stress fiber assembly)|go:"GO:0051497"(negative regulation of stress fiber assembly)|go:"GO:0071346"(cellular response to interferon-gamma)|go:"GO:1905168"(positive regulation of double-strand break repair via homologous recombination)|go:"GO:2000146"(negative regulation of cell motility)|go:"GO:2000601"(positive regulation of Arp2/3 complex-mediated actin nucleation)|interpro:IPR000095(PAK-box/P21-Rho-binding)|interpro:IPR000697(EVH1)|interpro:IPR003124(Actin-binding WH2)|interpro:IPR011026(Wiscott-Aldrich syndrome, C-terminal)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR027641|interpro:IPR033927|interpro:IPR036936|mint:P70315|dip:DIP-36426N	-	-	-	figure legend:ST5|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2020/07/08	2020/08/14	rogid:lGOg72Osvz8819m674JzGUcHEj483332	rogid:HbZjGXPVByZsiabjyX43YwKnJeA10090	rigid:TI970OpDTQBsW8Jte5hEzoJp8zg	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P9WJB9	uniprotkb:P70315	intact:EBI-25767670|uniprotkb:L0TE21|uniprotkb:O69744|uniprotkb:Q7D4P0	intact:EBI-644195|ensembl:ENSMUSP00000033505	psi-mi:espl_myctu(display_long)|uniprotkb:espL(gene name)|psi-mi:espL(display_short)|uniprotkb:Rv3880c(locus name)	psi-mi:wasp_mouse(display_long)|uniprotkb:Was(gene name)|psi-mi:Was(display_short)|uniprotkb:Wasp(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2018)	doi:10.1093/nar/gkx1173|imex:IM-28235|pubmed:29165646	taxid:83332(myctu)|taxid:83332("Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)")	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0471"(MINT)	intact:EBI-25768868|imex:IM-28235-115	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	go:"GO:0003677"(DNA binding)|go:"GO:0005618"(cell wall)|go:"GO:0005886"(plasma membrane)|go:"GO:0052170"(suppression by symbiont of host innate immune response)|mint:P9WJB9|refseq:NP_218397.1|refseq:WP_003399988.1|interpro:IPR036894|interpro:IPR004401(Conserved hypothetical protein CHP00103)	refseq:NP_033541.1|ensembl:ENSMUSG00000031165(gene)|ensembl:ENSMUST00000033505(transcript)|go:"GO:0002625"(regulation of T cell antigen processing and presentation)|go:"GO:0003779"(actin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0005884"(actin filament)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0006955"(immune response)|go:"GO:0008064"(regulation of actin polymerization or depolymerization)|go:"GO:0008154"(actin polymerization or depolymerization)|go:"GO:0010591"(regulation of lamellipodium assembly)|go:"GO:0012506"(vesicle membrane)|go:"GO:0016197"(endosomal transport)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030041"(actin filament polymerization)|go:"GO:0030048"(actin filament-based movement)|go:"GO:0031267"(small GTPase binding)|go:"GO:0032488"(Cdc42 protein signal transduction)|go:"GO:0035861"(site of double-strand break)|go:"GO:0042110"(T cell activation)|go:"GO:0042802"(identical protein binding)|go:"GO:0043274"(phospholipase binding)|go:"GO:0045335"(phagocytic vesicle)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0051492"(regulation of stress fiber assembly)|go:"GO:0051497"(negative regulation of stress fiber assembly)|go:"GO:0071346"(cellular response to interferon-gamma)|go:"GO:1905168"(positive regulation of double-strand break repair via homologous recombination)|go:"GO:2000146"(negative regulation of cell motility)|go:"GO:2000601"(positive regulation of Arp2/3 complex-mediated actin nucleation)|interpro:IPR000095(PAK-box/P21-Rho-binding)|interpro:IPR000697(EVH1)|interpro:IPR003124(Actin-binding WH2)|interpro:IPR011026(Wiscott-Aldrich syndrome, C-terminal)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR027641|interpro:IPR033927|interpro:IPR036936|mint:P70315|dip:DIP-36426N	-	-	-	figure legend:ST5|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2020/07/08	2020/08/14	rogid:BspTx2RZuhJaQ319NBDIyOreqfE83332	rogid:HbZjGXPVByZsiabjyX43YwKnJeA10090	rigid:50xDHJSsF+7eBOHnq1j3zvqDIIY	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P9WIT1	uniprotkb:P70315	intact:EBI-25767539|uniprotkb:L0TBU2|uniprotkb:Q50685|uniprotkb:Q7D7C5	intact:EBI-644195|ensembl:ENSMUSP00000033505	psi-mi:y2280_myctu(display_long)|uniprotkb:Rv2280(locus name)	psi-mi:wasp_mouse(display_long)|uniprotkb:Was(gene name)|psi-mi:Was(display_short)|uniprotkb:Wasp(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2018)	doi:10.1093/nar/gkx1173|imex:IM-28235|pubmed:29165646	taxid:83332(myctu)|taxid:83332("Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)")	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0471"(MINT)	intact:EBI-25768862|imex:IM-28235-113	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	go:"GO:0005618"(cell wall)|go:"GO:0005886"(plasma membrane)|go:"GO:0016491"(oxidoreductase activity)|go:"GO:0071949"(FAD binding)|interpro:IPR016169(CO dehydrogenase flavoprotein-like, FAD-binding, subdomain 2)|mint:P9WIT1|refseq:WP_003411690.1|interpro:IPR016166(FAD-binding, type 2)|interpro:IPR036318|interpro:IPR016164(FAD-linked oxidase-like, C-terminal)|interpro:IPR004113(FAD-linked oxidase, C-terminal)|interpro:IPR006094(FAD linked oxidase, N-terminal)|interpro:IPR016171(Vanillyl-alcohol oxidase, C-terminal subdomain 2)	refseq:NP_033541.1|ensembl:ENSMUSG00000031165(gene)|ensembl:ENSMUST00000033505(transcript)|go:"GO:0002625"(regulation of T cell antigen processing and presentation)|go:"GO:0003779"(actin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0005884"(actin filament)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0006955"(immune response)|go:"GO:0008064"(regulation of actin polymerization or depolymerization)|go:"GO:0008154"(actin polymerization or depolymerization)|go:"GO:0010591"(regulation of lamellipodium assembly)|go:"GO:0012506"(vesicle membrane)|go:"GO:0016197"(endosomal transport)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030041"(actin filament polymerization)|go:"GO:0030048"(actin filament-based movement)|go:"GO:0031267"(small GTPase binding)|go:"GO:0032488"(Cdc42 protein signal transduction)|go:"GO:0035861"(site of double-strand break)|go:"GO:0042110"(T cell activation)|go:"GO:0042802"(identical protein binding)|go:"GO:0043274"(phospholipase binding)|go:"GO:0045335"(phagocytic vesicle)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0051492"(regulation of stress fiber assembly)|go:"GO:0051497"(negative regulation of stress fiber assembly)|go:"GO:0071346"(cellular response to interferon-gamma)|go:"GO:1905168"(positive regulation of double-strand break repair via homologous recombination)|go:"GO:2000146"(negative regulation of cell motility)|go:"GO:2000601"(positive regulation of Arp2/3 complex-mediated actin nucleation)|interpro:IPR000095(PAK-box/P21-Rho-binding)|interpro:IPR000697(EVH1)|interpro:IPR003124(Actin-binding WH2)|interpro:IPR011026(Wiscott-Aldrich syndrome, C-terminal)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR027641|interpro:IPR033927|interpro:IPR036936|mint:P70315|dip:DIP-36426N	-	-	-	figure legend:ST5|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2020/07/08	2020/08/14	rogid:TvFI3uuw9zREl1q0DeWIsHmCSEk83332	rogid:HbZjGXPVByZsiabjyX43YwKnJeA10090	rigid:7AIxmVtNwP6HXedZyf+mRoo3W7U	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:L7N684	uniprotkb:P70315	intact:EBI-25768007|uniprotkb:I6XZY1	intact:EBI-644195|ensembl:ENSMUSP00000033505	psi-mi:l7n684_myctu(display_long)|uniprotkb:Rv2141c(locus name)	psi-mi:wasp_mouse(display_long)|uniprotkb:Was(gene name)|psi-mi:Was(display_short)|uniprotkb:Wasp(gene name synonym)	psi-mi:"MI:0397"(two hybrid array)	Yang et al. (2018)	doi:10.1093/nar/gkx1173|imex:IM-28235|pubmed:29165646	taxid:83332(myctu)|taxid:83332("Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)")	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0471"(MINT)	intact:EBI-25768856|imex:IM-28235-219	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	go:"GO:0006526"(arginine biosynthetic process)|go:"GO:0008777"(acetylornithine deacetylase activity)|mint:L7N684|refseq:WP_003411121.1|refseq:YP_177864.1|interpro:IPR001261(ArgE/DapE/ACY1/CPG2/YscS, conserved site)|interpro:IPR036264|interpro:IPR002933(Peptidase M20)|interpro:IPR011650(Peptidase M20, dimerisation)	refseq:NP_033541.1|ensembl:ENSMUSG00000031165(gene)|ensembl:ENSMUST00000033505(transcript)|go:"GO:0002625"(regulation of T cell antigen processing and presentation)|go:"GO:0003779"(actin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0005884"(actin filament)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0006955"(immune response)|go:"GO:0008064"(regulation of actin polymerization or depolymerization)|go:"GO:0008154"(actin polymerization or depolymerization)|go:"GO:0010591"(regulation of lamellipodium assembly)|go:"GO:0012506"(vesicle membrane)|go:"GO:0016197"(endosomal transport)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030041"(actin filament polymerization)|go:"GO:0030048"(actin filament-based movement)|go:"GO:0031267"(small GTPase binding)|go:"GO:0032488"(Cdc42 protein signal transduction)|go:"GO:0035861"(site of double-strand break)|go:"GO:0042110"(T cell activation)|go:"GO:0042802"(identical protein binding)|go:"GO:0043274"(phospholipase binding)|go:"GO:0045335"(phagocytic vesicle)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0051492"(regulation of stress fiber assembly)|go:"GO:0051497"(negative regulation of stress fiber assembly)|go:"GO:0071346"(cellular response to interferon-gamma)|go:"GO:1905168"(positive regulation of double-strand break repair via homologous recombination)|go:"GO:2000146"(negative regulation of cell motility)|go:"GO:2000601"(positive regulation of Arp2/3 complex-mediated actin nucleation)|interpro:IPR000095(PAK-box/P21-Rho-binding)|interpro:IPR000697(EVH1)|interpro:IPR003124(Actin-binding WH2)|interpro:IPR011026(Wiscott-Aldrich syndrome, C-terminal)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR027641|interpro:IPR033927|interpro:IPR036936|mint:P70315|dip:DIP-36426N	-	-	-	figure legend:ST5|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2020/07/08	2020/08/14	rogid:c/gr5TMeB+nx0CZHLBZI7YeVioo83332	rogid:HbZjGXPVByZsiabjyX43YwKnJeA10090	rigid:mO/H+4f+mm/HpToLR6wHnJd/a/0	false	-	-	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:P70315	uniprotkb:P9WHV1	intact:EBI-644195|ensembl:ENSMUSP00000033505	intact:EBI-25768182|uniprotkb:L0TB68|uniprotkb:P65788|uniprotkb:P71921	psi-mi:wasp_mouse(display_long)|uniprotkb:Was(gene name)|psi-mi:Was(display_short)|uniprotkb:Wasp(gene name synonym)	psi-mi:proa_myctu(display_long)|uniprotkb:proA(gene name)|psi-mi:proA(display_short)|uniprotkb:Glutamate-5-semialdehyde dehydrogenase(gene name synonym)|uniprotkb:Glutamyl-gamma-semialdehyde dehydrogenase(gene name synonym)|uniprotkb:MTCY428.20(orf name)|uniprotkb:Rv2427c(locus name)	psi-mi:"MI:0809"(bimolecular fluorescence complementation)	Yang et al. (2018)	doi:10.1093/nar/gkx1173|imex:IM-28235|pubmed:29165646	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:83332(myctu)|taxid:83332("Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)")	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0471"(MINT)	intact:EBI-25772787|imex:IM-28235-348	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_033541.1|ensembl:ENSMUSG00000031165(gene)|ensembl:ENSMUST00000033505(transcript)|go:"GO:0002625"(regulation of T cell antigen processing and presentation)|go:"GO:0003779"(actin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0005884"(actin filament)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0006955"(immune response)|go:"GO:0008064"(regulation of actin polymerization or depolymerization)|go:"GO:0008154"(actin polymerization or depolymerization)|go:"GO:0010591"(regulation of lamellipodium assembly)|go:"GO:0012506"(vesicle membrane)|go:"GO:0016197"(endosomal transport)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030041"(actin filament polymerization)|go:"GO:0030048"(actin filament-based movement)|go:"GO:0031267"(small GTPase binding)|go:"GO:0032488"(Cdc42 protein signal transduction)|go:"GO:0035861"(site of double-strand break)|go:"GO:0042110"(T cell activation)|go:"GO:0042802"(identical protein binding)|go:"GO:0043274"(phospholipase binding)|go:"GO:0045335"(phagocytic vesicle)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0051492"(regulation of stress fiber assembly)|go:"GO:0051497"(negative regulation of stress fiber assembly)|go:"GO:0071346"(cellular response to interferon-gamma)|go:"GO:1905168"(positive regulation of double-strand break repair via homologous recombination)|go:"GO:2000146"(negative regulation of cell motility)|go:"GO:2000601"(positive regulation of Arp2/3 complex-mediated actin nucleation)|interpro:IPR000095(PAK-box/P21-Rho-binding)|interpro:IPR000697(EVH1)|interpro:IPR003124(Actin-binding WH2)|interpro:IPR011026(Wiscott-Aldrich syndrome, C-terminal)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR027641|interpro:IPR033927|interpro:IPR036936|mint:P70315|dip:DIP-36426N	go:"GO:0004350"(glutamate-5-semialdehyde dehydrogenase activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0050661"(NADP binding)|go:"GO:0055129"(L-proline biosynthetic process)|go:"GO:0005829"(cytosol)|mint:P9WHV1|refseq:NP_216943.1|refseq:WP_003412516.1|interpro:IPR016161(Aldehyde/histidinol dehydrogenase)|interpro:IPR016163(Aldehyde dehydrogenase, C-terminal)|interpro:IPR016162(Aldehyde dehydrogenase, N-terminal)|interpro:IPR015590(Aldehyde dehydrogenase)|interpro:IPR020593|interpro:IPR012134(Glutamate-5-semialdehyde dehydrogenase)|interpro:IPR000965(Gamma-glutamyl phosphate reductase GPR)	-	-	-	figure legend:f5e|comment:It is not explained in the paper the exact tags that have been used in the BiFC experiment.|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2020/07/08	2020/08/07	rogid:HbZjGXPVByZsiabjyX43YwKnJeA10090	rogid:fzCkUX2wrGj0ZK0LOaeT+UNWpwI83332	rigid:ag13eVPbZjFLnDH4XYO2qToSAr8	false	bifc tag:?-?	bifc tag:?-?	-	-	psi-mi:"MI:0867"(tag visualisation by fluorescence)	psi-mi:"MI:0867"(tag visualisation by fluorescence)