#ID(s) interactor A ID(s) interactor B Alt. ID(s) interactor A Alt. ID(s) interactor B Alias(es) interactor A Alias(es) interactor B Interaction detection method(s) Publication 1st author(s) Publication Identifier(s) Taxid interactor A Taxid interactor B Interaction type(s) Source database(s) Interaction identifier(s) Confidence value(s) Expansion method(s) Biological role(s) interactor A Biological role(s) interactor B Experimental role(s) interactor A Experimental role(s) interactor B Type(s) interactor A Type(s) interactor B Xref(s) interactor A Xref(s) interactor B Interaction Xref(s) Annotation(s) interactor A Annotation(s) interactor B Interaction annotation(s) Host organism(s) Interaction parameter(s) Creation date Update date Checksum(s) interactor A Checksum(s) interactor B Interaction Checksum(s) Negative Feature(s) interactor A Feature(s) interactor B Stoichiometry(s) interactor A Stoichiometry(s) interactor B Identification method participant A Identification method participant B uniprotkb:Q08708 uniprotkb:A8K4G0 intact:EBI-3915344|ensembl:ENSP00000329507 intact:EBI-26499879|ensembl:ENSP00000376397|uniprotkb:Q1EG73|uniprotkb:Q8IX40|uniprotkb:Q8N6D1 psi-mi:clm6_human(display_long)|uniprotkb:CD300C(gene name)|psi-mi:CD300C(display_short)|uniprotkb:CMRF35(gene name synonym)|uniprotkb:CMRF35A(gene name synonym)|uniprotkb:CMRF35A1(gene name synonym)|uniprotkb:IGSF16(gene name synonym)|uniprotkb:CD300 antigen-like family member C(gene name synonym)|uniprotkb:CMRF35-A1(gene name synonym)|uniprotkb:Immunoglobulin superfamily member 16(gene name synonym) psi-mi:clm7_human(display_long)|uniprotkb:CD300LB(gene name)|psi-mi:CD300LB(display_short)|uniprotkb:CD300B(gene name synonym)|uniprotkb:CLM7(gene name synonym)|uniprotkb:CMRF35A2(gene name synonym)|uniprotkb:IREM3(gene name synonym)|uniprotkb:LMIR5(gene name synonym)|uniprotkb:TREM5(gene name synonym)|uniprotkb:CD300 antigen-like family member B(gene name synonym)|uniprotkb:CMRF35-A2(gene name synonym)|uniprotkb:Immune receptor expressed on myeloid cells 3(gene name synonym)|uniprotkb:Leukocyte mono-Ig-like receptor 5(gene name synonym)|uniprotkb:Triggering receptor expressed on myeloid cells 5(gene name synonym)|uniprotkb:UNQ2530/PRO6029(orf name) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Martínez-Barriocanal et al. (2017) pubmed:29051512|imex:IM-28607 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0486"(UniProt) intact:EBI-26516799|imex:IM-28607-1 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_006669.1|ensembl:ENSG00000167850(gene)|ensembl:ENST00000330793(transcript)|go:"GO:0002376"(immune system process)|go:"GO:0004888"(transmembrane signaling receptor activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006968"(cellular defense response)|interpro:IPR003599(Immunoglobulin subtype)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR013106(Immunoglobulin V-set)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR036179|reactome:R-HSA-198933 ensembl:ENSG00000178789(gene)|ensembl:ENST00000392621(transcript)|go:"GO:0002376"(immune system process)|go:"GO:0004888"(transmembrane signaling receptor activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0042802"(identical protein binding)|interpro:IPR003599(Immunoglobulin subtype)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR013106(Immunoglobulin V-set)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR036179|reactome:R-HSA-198933|reactome:R-HSA-2172127|refseq:NP_777552.3 - - - figure legend:Fig. 2A|caution:"Regarding the CD300b R95G-Q97G mutant:there is no \"Q\" (Glutamine) at residue 97. There is a \"D\" (Aspartic acid) at this position. Details of mutations given in Table S1 refer to an N97A mutation, which cannot be found in the main text, and this table does not list either an Q97G or D97G mutant."|dataset:Rare diseases - Interactions investigated in the context of Rare genetic disease|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9534(chlae-cos_7)|taxid:9534(Cercopithecus aethiops simian cells transformed with SV40) - 2020/12/09 2020/12/09 rogid:HwcMCrpmh1FZLbDHCsrUlfZPcFU9606 rogid:CiZcMyJI10I18uugrUsh40aIEUU9606 rigid:2QdmFHBM9FejhTTL9w80Jwy45dY false ha tag:?-? flag tag:?-?|mutation with no effect:95-95,97-97|mutation decreasing interaction strength:28-29 - - psi-mi:"MI:0705"(anti tag western blot) psi-mi:"MI:0705"(anti tag western blot) uniprotkb:A8K4G0 uniprotkb:A8K4G0 intact:EBI-26499879|ensembl:ENSP00000376397|uniprotkb:Q1EG73|uniprotkb:Q8IX40|uniprotkb:Q8N6D1 intact:EBI-26499879|ensembl:ENSP00000376397|uniprotkb:Q1EG73|uniprotkb:Q8IX40|uniprotkb:Q8N6D1 psi-mi:clm7_human(display_long)|uniprotkb:CD300LB(gene name)|psi-mi:CD300LB(display_short)|uniprotkb:CD300B(gene name synonym)|uniprotkb:CLM7(gene name synonym)|uniprotkb:CMRF35A2(gene name synonym)|uniprotkb:IREM3(gene name synonym)|uniprotkb:LMIR5(gene name synonym)|uniprotkb:TREM5(gene name synonym)|uniprotkb:CD300 antigen-like family member B(gene name synonym)|uniprotkb:CMRF35-A2(gene name synonym)|uniprotkb:Immune receptor expressed on myeloid cells 3(gene name synonym)|uniprotkb:Leukocyte mono-Ig-like receptor 5(gene name synonym)|uniprotkb:Triggering receptor expressed on myeloid cells 5(gene name synonym)|uniprotkb:UNQ2530/PRO6029(orf name) psi-mi:clm7_human(display_long)|uniprotkb:CD300LB(gene name)|psi-mi:CD300LB(display_short)|uniprotkb:CD300B(gene name synonym)|uniprotkb:CLM7(gene name synonym)|uniprotkb:CMRF35A2(gene name synonym)|uniprotkb:IREM3(gene name synonym)|uniprotkb:LMIR5(gene name synonym)|uniprotkb:TREM5(gene name synonym)|uniprotkb:CD300 antigen-like family member B(gene name synonym)|uniprotkb:CMRF35-A2(gene name synonym)|uniprotkb:Immune receptor expressed on myeloid cells 3(gene name synonym)|uniprotkb:Leukocyte mono-Ig-like receptor 5(gene name synonym)|uniprotkb:Triggering receptor expressed on myeloid cells 5(gene name synonym)|uniprotkb:UNQ2530/PRO6029(orf name) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Martínez-Barriocanal et al. (2017) pubmed:29051512|imex:IM-28607 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0486"(UniProt) intact:EBI-26518393|imex:IM-28607-3 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000178789(gene)|ensembl:ENST00000392621(transcript)|go:"GO:0002376"(immune system process)|go:"GO:0004888"(transmembrane signaling receptor activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0042802"(identical protein binding)|interpro:IPR003599(Immunoglobulin subtype)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR013106(Immunoglobulin V-set)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR036179|reactome:R-HSA-198933|reactome:R-HSA-2172127|refseq:NP_777552.3 ensembl:ENSG00000178789(gene)|ensembl:ENST00000392621(transcript)|go:"GO:0002376"(immune system process)|go:"GO:0004888"(transmembrane signaling receptor activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0042802"(identical protein binding)|interpro:IPR003599(Immunoglobulin subtype)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR013106(Immunoglobulin V-set)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR036179|reactome:R-HSA-198933|reactome:R-HSA-2172127|refseq:NP_777552.3 - - - figure legend:Fig. 2B, Fig. 4|dataset:Rare diseases - Interactions investigated in the context of Rare genetic disease|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9534(chlae-cos_7)|taxid:9534(Cercopithecus aethiops simian cells transformed with SV40) - 2020/12/09 2020/12/09 rogid:CiZcMyJI10I18uugrUsh40aIEUU9606 rogid:CiZcMyJI10I18uugrUsh40aIEUU9606 rigid:8xYPpPjdGZRnS0Hf0MyoppTWslc false ha tag:?-? flag tag:?-?|mutation decreasing interaction strength:28-29 - - psi-mi:"MI:0705"(anti tag western blot) psi-mi:"MI:0705"(anti tag western blot) uniprotkb:A8K4G0 uniprotkb:A8K4G0 intact:EBI-26499879|ensembl:ENSP00000376397|uniprotkb:Q1EG73|uniprotkb:Q8IX40|uniprotkb:Q8N6D1 intact:EBI-26499879|ensembl:ENSP00000376397|uniprotkb:Q1EG73|uniprotkb:Q8IX40|uniprotkb:Q8N6D1 psi-mi:clm7_human(display_long)|uniprotkb:CD300LB(gene name)|psi-mi:CD300LB(display_short)|uniprotkb:CD300B(gene name synonym)|uniprotkb:CLM7(gene name synonym)|uniprotkb:CMRF35A2(gene name synonym)|uniprotkb:IREM3(gene name synonym)|uniprotkb:LMIR5(gene name synonym)|uniprotkb:TREM5(gene name synonym)|uniprotkb:CD300 antigen-like family member B(gene name synonym)|uniprotkb:CMRF35-A2(gene name synonym)|uniprotkb:Immune receptor expressed on myeloid cells 3(gene name synonym)|uniprotkb:Leukocyte mono-Ig-like receptor 5(gene name synonym)|uniprotkb:Triggering receptor expressed on myeloid cells 5(gene name synonym)|uniprotkb:UNQ2530/PRO6029(orf name) psi-mi:clm7_human(display_long)|uniprotkb:CD300LB(gene name)|psi-mi:CD300LB(display_short)|uniprotkb:CD300B(gene name synonym)|uniprotkb:CLM7(gene name synonym)|uniprotkb:CMRF35A2(gene name synonym)|uniprotkb:IREM3(gene name synonym)|uniprotkb:LMIR5(gene name synonym)|uniprotkb:TREM5(gene name synonym)|uniprotkb:CD300 antigen-like family member B(gene name synonym)|uniprotkb:CMRF35-A2(gene name synonym)|uniprotkb:Immune receptor expressed on myeloid cells 3(gene name synonym)|uniprotkb:Leukocyte mono-Ig-like receptor 5(gene name synonym)|uniprotkb:Triggering receptor expressed on myeloid cells 5(gene name synonym)|uniprotkb:UNQ2530/PRO6029(orf name) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Martínez-Barriocanal et al. (2017) pubmed:29051512|imex:IM-28607 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0486"(UniProt) intact:EBI-26518406|imex:IM-28607-5 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000178789(gene)|ensembl:ENST00000392621(transcript)|go:"GO:0002376"(immune system process)|go:"GO:0004888"(transmembrane signaling receptor activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0042802"(identical protein binding)|interpro:IPR003599(Immunoglobulin subtype)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR013106(Immunoglobulin V-set)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR036179|reactome:R-HSA-198933|reactome:R-HSA-2172127|refseq:NP_777552.3 ensembl:ENSG00000178789(gene)|ensembl:ENST00000392621(transcript)|go:"GO:0002376"(immune system process)|go:"GO:0004888"(transmembrane signaling receptor activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0042802"(identical protein binding)|interpro:IPR003599(Immunoglobulin subtype)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR013106(Immunoglobulin V-set)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR036179|reactome:R-HSA-198933|reactome:R-HSA-2172127|refseq:NP_777552.3 - - - figure legend:Fig. 2B|dataset:Rare diseases - Interactions investigated in the context of Rare genetic disease|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9534(chlae-cos_7)|taxid:9534(Cercopithecus aethiops simian cells transformed with SV40) - 2020/12/09 2020/12/09 rogid:CiZcMyJI10I18uugrUsh40aIEUU9606 rogid:CiZcMyJI10I18uugrUsh40aIEUU9606 rigid:8xYPpPjdGZRnS0Hf0MyoppTWslc false flag tag:?-? ha tag:?-?|mutation decreasing interaction strength:28-29 - - psi-mi:"MI:0705"(anti tag western blot) psi-mi:"MI:0705"(anti tag western blot) uniprotkb:A8K4G0 uniprotkb:A8K4G0 intact:EBI-26499879|ensembl:ENSP00000376397|uniprotkb:Q1EG73|uniprotkb:Q8IX40|uniprotkb:Q8N6D1 intact:EBI-26499879|ensembl:ENSP00000376397|uniprotkb:Q1EG73|uniprotkb:Q8IX40|uniprotkb:Q8N6D1 psi-mi:clm7_human(display_long)|uniprotkb:CD300LB(gene name)|psi-mi:CD300LB(display_short)|uniprotkb:CD300B(gene name synonym)|uniprotkb:CLM7(gene name synonym)|uniprotkb:CMRF35A2(gene name synonym)|uniprotkb:IREM3(gene name synonym)|uniprotkb:LMIR5(gene name synonym)|uniprotkb:TREM5(gene name synonym)|uniprotkb:CD300 antigen-like family member B(gene name synonym)|uniprotkb:CMRF35-A2(gene name synonym)|uniprotkb:Immune receptor expressed on myeloid cells 3(gene name synonym)|uniprotkb:Leukocyte mono-Ig-like receptor 5(gene name synonym)|uniprotkb:Triggering receptor expressed on myeloid cells 5(gene name synonym)|uniprotkb:UNQ2530/PRO6029(orf name) psi-mi:clm7_human(display_long)|uniprotkb:CD300LB(gene name)|psi-mi:CD300LB(display_short)|uniprotkb:CD300B(gene name synonym)|uniprotkb:CLM7(gene name synonym)|uniprotkb:CMRF35A2(gene name synonym)|uniprotkb:IREM3(gene name synonym)|uniprotkb:LMIR5(gene name synonym)|uniprotkb:TREM5(gene name synonym)|uniprotkb:CD300 antigen-like family member B(gene name synonym)|uniprotkb:CMRF35-A2(gene name synonym)|uniprotkb:Immune receptor expressed on myeloid cells 3(gene name synonym)|uniprotkb:Leukocyte mono-Ig-like receptor 5(gene name synonym)|uniprotkb:Triggering receptor expressed on myeloid cells 5(gene name synonym)|uniprotkb:UNQ2530/PRO6029(orf name) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Martínez-Barriocanal et al. (2017) pubmed:29051512|imex:IM-28607 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0486"(UniProt) intact:EBI-26518417|imex:IM-28607-21 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000178789(gene)|ensembl:ENST00000392621(transcript)|go:"GO:0002376"(immune system process)|go:"GO:0004888"(transmembrane signaling receptor activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0042802"(identical protein binding)|interpro:IPR003599(Immunoglobulin subtype)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR013106(Immunoglobulin V-set)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR036179|reactome:R-HSA-198933|reactome:R-HSA-2172127|refseq:NP_777552.3 ensembl:ENSG00000178789(gene)|ensembl:ENST00000392621(transcript)|go:"GO:0002376"(immune system process)|go:"GO:0004888"(transmembrane signaling receptor activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0042802"(identical protein binding)|interpro:IPR003599(Immunoglobulin subtype)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR013106(Immunoglobulin V-set)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR036179|reactome:R-HSA-198933|reactome:R-HSA-2172127|refseq:NP_777552.3 - - - figure legend:Fig. 2B|dataset:Rare diseases - Interactions investigated in the context of Rare genetic disease|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9534(chlae-cos_7)|taxid:9534(Cercopithecus aethiops simian cells transformed with SV40) - 2020/12/09 2020/12/09 rogid:CiZcMyJI10I18uugrUsh40aIEUU9606 rogid:CiZcMyJI10I18uugrUsh40aIEUU9606 rigid:8xYPpPjdGZRnS0Hf0MyoppTWslc false flag tag:?-?|mutation disrupting interaction strength:28-29 ha tag:?-?|mutation disrupting interaction strength:28-29 - - psi-mi:"MI:0705"(anti tag western blot) psi-mi:"MI:0705"(anti tag western blot) uniprotkb:Q6UXZ3 uniprotkb:A8K4G0 intact:EBI-4314468|ensembl:ENSP00000364501 intact:EBI-26499879|ensembl:ENSP00000376397|uniprotkb:Q1EG73|uniprotkb:Q8IX40|uniprotkb:Q8N6D1 psi-mi:clm5_human(display_long)|uniprotkb:CD300LD(gene name)|psi-mi:CD300LD(display_short)|uniprotkb:CD300D(gene name synonym)|uniprotkb:CMRF35A4(gene name synonym)|uniprotkb:CD300 antigen-like family member D(gene name synonym)|uniprotkb:CMRF35-A4(gene name synonym)|uniprotkb:UNQ9218/PRO28686(orf name) psi-mi:clm7_human(display_long)|uniprotkb:CD300LB(gene name)|psi-mi:CD300LB(display_short)|uniprotkb:CD300B(gene name synonym)|uniprotkb:CLM7(gene name synonym)|uniprotkb:CMRF35A2(gene name synonym)|uniprotkb:IREM3(gene name synonym)|uniprotkb:LMIR5(gene name synonym)|uniprotkb:TREM5(gene name synonym)|uniprotkb:CD300 antigen-like family member B(gene name synonym)|uniprotkb:CMRF35-A2(gene name synonym)|uniprotkb:Immune receptor expressed on myeloid cells 3(gene name synonym)|uniprotkb:Leukocyte mono-Ig-like receptor 5(gene name synonym)|uniprotkb:Triggering receptor expressed on myeloid cells 5(gene name synonym)|uniprotkb:UNQ2530/PRO6029(orf name) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Martínez-Barriocanal et al. (2017) pubmed:29051512|imex:IM-28607 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0486"(UniProt) intact:EBI-26518456|imex:IM-28607-7 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001108624.1|ensembl:ENSG00000204345(gene)|ensembl:ENST00000375352(transcript)|go:"GO:0002376"(immune system process)|go:"GO:0004888"(transmembrane signaling receptor activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0016021"(integral component of membrane)|interpro:IPR003599(Immunoglobulin subtype)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR013106(Immunoglobulin V-set)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR036179|reactome:R-HSA-198933 ensembl:ENSG00000178789(gene)|ensembl:ENST00000392621(transcript)|go:"GO:0002376"(immune system process)|go:"GO:0004888"(transmembrane signaling receptor activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0042802"(identical protein binding)|interpro:IPR003599(Immunoglobulin subtype)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR013106(Immunoglobulin V-set)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR036179|reactome:R-HSA-198933|reactome:R-HSA-2172127|refseq:NP_777552.3 - - - figure legend:Fig. 2C|dataset:Rare diseases - Interactions investigated in the context of Rare genetic disease|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9534(chlae-cos_7)|taxid:9534(Cercopithecus aethiops simian cells transformed with SV40) - 2020/12/09 2020/12/09 rogid:Z44M8MmLNTarCE2prDhXD6/kSPY9606 rogid:CiZcMyJI10I18uugrUsh40aIEUU9606 rigid:1PMB+qkF27htE3L6Hhk5LWwBepo false ha tag:?-? flag tag:?-?|mutation decreasing interaction strength:28-29 - - psi-mi:"MI:0705"(anti tag western blot) psi-mi:"MI:0705"(anti tag western blot) uniprotkb:Q496F6 uniprotkb:A8K4G0 intact:EBI-18010148|uniprotkb:B4DNS1|uniprotkb:Q7Z7I3|ensembl:ENSP00000376395 intact:EBI-26499879|ensembl:ENSP00000376397|uniprotkb:Q1EG73|uniprotkb:Q8IX40|uniprotkb:Q8N6D1 psi-mi:clm2_human(display_long)|uniprotkb:CD300 antigen-like family member E(gene name synonym)|uniprotkb:CMRF35-A5(gene name synonym)|uniprotkb:Immune receptor expressed on myeloid cells 2(gene name synonym)|uniprotkb:Polymeric immunoglobulin receptor 2(gene name synonym)|uniprotkb:CD300E(gene name)|psi-mi:CD300E(display_short)|uniprotkb:CD300LE(gene name synonym)|uniprotkb:CLM2(gene name synonym)|uniprotkb:CMRF35A5(gene name synonym)|uniprotkb:IREM2(gene name synonym) psi-mi:clm7_human(display_long)|uniprotkb:CD300LB(gene name)|psi-mi:CD300LB(display_short)|uniprotkb:CD300B(gene name synonym)|uniprotkb:CLM7(gene name synonym)|uniprotkb:CMRF35A2(gene name synonym)|uniprotkb:IREM3(gene name synonym)|uniprotkb:LMIR5(gene name synonym)|uniprotkb:TREM5(gene name synonym)|uniprotkb:CD300 antigen-like family member B(gene name synonym)|uniprotkb:CMRF35-A2(gene name synonym)|uniprotkb:Immune receptor expressed on myeloid cells 3(gene name synonym)|uniprotkb:Leukocyte mono-Ig-like receptor 5(gene name synonym)|uniprotkb:Triggering receptor expressed on myeloid cells 5(gene name synonym)|uniprotkb:UNQ2530/PRO6029(orf name) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Martínez-Barriocanal et al. (2017) pubmed:29051512|imex:IM-28607 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0486"(UniProt) intact:EBI-26518469|imex:IM-28607-9 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_852114.2|ensembl:ENSG00000186407(gene)|ensembl:ENST00000392619(transcript)|go:"GO:0002376"(immune system process)|go:"GO:0004888"(transmembrane signaling receptor activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0016021"(integral component of membrane)|interpro:IPR003599(Immunoglobulin subtype)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR013106(Immunoglobulin V-set)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR036179|reactome:R-HSA-198933|reactome:R-HSA-2172127 ensembl:ENSG00000178789(gene)|ensembl:ENST00000392621(transcript)|go:"GO:0002376"(immune system process)|go:"GO:0004888"(transmembrane signaling receptor activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0042802"(identical protein binding)|interpro:IPR003599(Immunoglobulin subtype)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR013106(Immunoglobulin V-set)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR036179|reactome:R-HSA-198933|reactome:R-HSA-2172127|refseq:NP_777552.3 - - - figure legend:Fig. 2C|dataset:Rare diseases - Interactions investigated in the context of Rare genetic disease|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9534(chlae-cos_7)|taxid:9534(Cercopithecus aethiops simian cells transformed with SV40) - 2020/12/09 2020/12/09 rogid:tmruU+BuI41lXctw0ZHhYSs7e209606 rogid:CiZcMyJI10I18uugrUsh40aIEUU9606 rigid:cGPQjyjftkRPF2vrdJrHn/9/e38 false ha tag:?-? mutation decreasing interaction strength:28-29|flag tag:?-? - - psi-mi:"MI:0705"(anti tag western blot) psi-mi:"MI:0705"(anti tag western blot) uniprotkb:Q9UGN4 uniprotkb:A8K4G0 intact:EBI-10320732|uniprotkb:Q9P0F3|uniprotkb:Q9HD97|uniprotkb:O95100|uniprotkb:Q9UBK4|uniprotkb:Q9UMT0|uniprotkb:A8MW96|uniprotkb:Q9UMS9|ensembl:ENSP00000353259 intact:EBI-26499879|ensembl:ENSP00000376397|uniprotkb:Q1EG73|uniprotkb:Q8IX40|uniprotkb:Q8N6D1 psi-mi:clm8_human(display_long)|uniprotkb:CD300A(gene name)|psi-mi:CD300A(display_short)|uniprotkb:CD300 antigen-like family member A(gene name synonym)|uniprotkb:CMRF-35-H9(gene name synonym)|uniprotkb:CMRF35-H(gene name synonym)|uniprotkb:CMRF35H(gene name synonym)|uniprotkb:IGSF12(gene name synonym)|uniprotkb:IRC1/IRC2(gene name synonym)|uniprotkb:Immunoglobulin superfamily member 12(gene name synonym)|uniprotkb:Inhibitory receptor protein 60(gene name synonym)|uniprotkb:NK inhibitory receptor(gene name synonym)|uniprotkb:HSPC083(orf name) psi-mi:clm7_human(display_long)|uniprotkb:CD300LB(gene name)|psi-mi:CD300LB(display_short)|uniprotkb:CD300B(gene name synonym)|uniprotkb:CLM7(gene name synonym)|uniprotkb:CMRF35A2(gene name synonym)|uniprotkb:IREM3(gene name synonym)|uniprotkb:LMIR5(gene name synonym)|uniprotkb:TREM5(gene name synonym)|uniprotkb:CD300 antigen-like family member B(gene name synonym)|uniprotkb:CMRF35-A2(gene name synonym)|uniprotkb:Immune receptor expressed on myeloid cells 3(gene name synonym)|uniprotkb:Leukocyte mono-Ig-like receptor 5(gene name synonym)|uniprotkb:Triggering receptor expressed on myeloid cells 5(gene name synonym)|uniprotkb:UNQ2530/PRO6029(orf name) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Martínez-Barriocanal et al. (2017) pubmed:29051512|imex:IM-28607 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0486"(UniProt) intact:EBI-26518479|imex:IM-28607-23 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001243770.1|refseq:NP_009192.2|ensembl:ENSG00000167851(gene)|ensembl:ENST00000360141(transcript)|go:"GO:0001786"(phosphatidylserine binding)|go:"GO:0002376"(immune system process)|go:"GO:0004888"(transmembrane signaling receptor activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0007155"(cell adhesion)|go:"GO:0008429"(phosphatidylethanolamine binding)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030889"(negative regulation of B cell proliferation)|go:"GO:0032516"(positive regulation of phosphoprotein phosphatase activity)|go:"GO:0033007"(negative regulation of mast cell activation involved in immune response)|go:"GO:0034125"(negative regulation of MyD88-dependent toll-like receptor signaling pathway)|go:"GO:0038023"(signaling receptor activity)|go:"GO:0043305"(negative regulation of mast cell degranulation)|go:"GO:0043407"(negative regulation of MAP kinase activity)|go:"GO:0048147"(negative regulation of fibroblast proliferation)|go:"GO:0050856"(regulation of T cell receptor signaling pathway)|go:"GO:0050859"(negative regulation of B cell receptor signaling pathway)|go:"GO:0051134"(negative regulation of NK T cell activation)|go:"GO:0060101"(negative regulation of phagocytosis, engulfment)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070821"(tertiary granule membrane)|go:"GO:0101003"(ficolin-1-rich granule membrane)|go:"GO:1902564"(negative regulation of neutrophil activation)|go:"GO:1902567"(negative regulation of eosinophil activation)|go:"GO:1902569"(negative regulation of activation of Janus kinase activity)|go:"GO:2000417"(negative regulation of eosinophil migration)|interpro:IPR003599(Immunoglobulin subtype)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR013106(Immunoglobulin V-set)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR036179|rcsb pdb:2Q87|reactome:R-HSA-198933|reactome:R-HSA-6798695|refseq:NP_001317386.1 ensembl:ENSG00000178789(gene)|ensembl:ENST00000392621(transcript)|go:"GO:0002376"(immune system process)|go:"GO:0004888"(transmembrane signaling receptor activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0042802"(identical protein binding)|interpro:IPR003599(Immunoglobulin subtype)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR013106(Immunoglobulin V-set)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR036179|reactome:R-HSA-198933|reactome:R-HSA-2172127|refseq:NP_777552.3 - - - figure legend:Fig. 2D|dataset:Rare diseases - Interactions investigated in the context of Rare genetic disease|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9534(chlae-cos_7)|taxid:9534(Cercopithecus aethiops simian cells transformed with SV40) - 2020/12/09 2020/12/09 rogid:SNAo4w52ox+ncDDKbu9Zv9EazQo9606 rogid:CiZcMyJI10I18uugrUsh40aIEUU9606 rigid:lxXlNm5vZxfx2u3LovtsqCQazzc false ha tag:?-? mutation decreasing interaction strength:28-29|flag tag:?-? - - psi-mi:"MI:0705"(anti tag western blot) psi-mi:"MI:0705"(anti tag western blot) uniprotkb:Q8TDQ1 uniprotkb:A8K4G0 intact:EBI-7381492|uniprotkb:Q6UX24|uniprotkb:B2RCL2|uniprotkb:Q7Z7I4|uniprotkb:Q7Z6A6|uniprotkb:C9JDN3|uniprotkb:Q7Z7I5|intact:MINT-8020158|uniprotkb:Q8N6D0|uniprotkb:Q3Y6P0|uniprotkb:Q8NAF5|ensembl:ENSP00000327075 intact:EBI-26499879|ensembl:ENSP00000376397|uniprotkb:Q1EG73|uniprotkb:Q8IX40|uniprotkb:Q8N6D1 psi-mi:clm1_human(display_long)|uniprotkb:CD300LF(gene name)|psi-mi:CD300LF(display_short)|uniprotkb:CD300 antigen-like family member F(gene name synonym)|uniprotkb:CD300F(gene name synonym)|uniprotkb:CLM1(gene name synonym)|uniprotkb:IGSF13(gene name synonym)|uniprotkb:IREM1(gene name synonym)|uniprotkb:Immune receptor expressed on myeloid cells 1(gene name synonym)|uniprotkb:Immunoglobulin superfamily member 13(gene name synonym)|uniprotkb:NK inhibitory receptor(gene name synonym)|uniprotkb:NKIR(gene name synonym)|uniprotkb:UNQ3105/PRO10111(orf name) psi-mi:clm7_human(display_long)|uniprotkb:CD300LB(gene name)|psi-mi:CD300LB(display_short)|uniprotkb:CD300B(gene name synonym)|uniprotkb:CLM7(gene name synonym)|uniprotkb:CMRF35A2(gene name synonym)|uniprotkb:IREM3(gene name synonym)|uniprotkb:LMIR5(gene name synonym)|uniprotkb:TREM5(gene name synonym)|uniprotkb:CD300 antigen-like family member B(gene name synonym)|uniprotkb:CMRF35-A2(gene name synonym)|uniprotkb:Immune receptor expressed on myeloid cells 3(gene name synonym)|uniprotkb:Leukocyte mono-Ig-like receptor 5(gene name synonym)|uniprotkb:Triggering receptor expressed on myeloid cells 5(gene name synonym)|uniprotkb:UNQ2530/PRO6029(orf name) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Martínez-Barriocanal et al. (2017) pubmed:29051512|imex:IM-28607 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0486"(UniProt) intact:EBI-26518489|imex:IM-28607-11 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_620587.2|refseq:NP_001276011.1|refseq:NP_001276012.1|refseq:NP_001276013.1|refseq:NP_001276014.1|refseq:NP_001276015.1|refseq:NP_001276016.1|ensembl:ENSG00000186074(gene)|ensembl:ENST00000326165(transcript)|go:"GO:0001786"(phosphatidylserine binding)|go:"GO:0002376"(immune system process)|go:"GO:0004888"(transmembrane signaling receptor activity)|go:"GO:0005136"(interleukin-4 receptor binding)|go:"GO:0005886"(plasma membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0033004"(negative regulation of mast cell activation)|go:"GO:0034125"(negative regulation of MyD88-dependent toll-like receptor signaling pathway)|go:"GO:0035666"(TRIF-dependent toll-like receptor signaling pathway)|go:"GO:0035772"(interleukin-13-mediated signaling pathway)|go:"GO:0042802"(identical protein binding)|go:"GO:0097001"(ceramide binding)|go:"GO:1902216"(positive regulation of interleukin-4-mediated signaling pathway)|go:"GO:2000426"(negative regulation of apoptotic cell clearance)|go:"GO:2000427"(positive regulation of apoptotic cell clearance)|interpro:IPR003599(Immunoglobulin subtype)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR013106(Immunoglobulin V-set)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR036179|rcsb pdb:2NMS|reactome:R-HSA-198933 ensembl:ENSG00000178789(gene)|ensembl:ENST00000392621(transcript)|go:"GO:0002376"(immune system process)|go:"GO:0004888"(transmembrane signaling receptor activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0042802"(identical protein binding)|interpro:IPR003599(Immunoglobulin subtype)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR013106(Immunoglobulin V-set)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR036179|reactome:R-HSA-198933|reactome:R-HSA-2172127|refseq:NP_777552.3 - comment:mint - figure legend:Fig. 2D|dataset:Rare diseases - Interactions investigated in the context of Rare genetic disease|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9534(chlae-cos_7)|taxid:9534(Cercopithecus aethiops simian cells transformed with SV40) - 2020/12/09 2020/12/09 rogid:cRoagmELrMitO+yvNY3O82t8vQY9606 rogid:CiZcMyJI10I18uugrUsh40aIEUU9606 rigid:RU8m5h9n3VtPU5Zxi7CFgh2gDkM false ha tag:?-? mutation decreasing interaction strength:28-29|flag tag:?-? - - psi-mi:"MI:0705"(anti tag western blot) psi-mi:"MI:0705"(anti tag western blot) uniprotkb:A8K4G0 uniprotkb:A8K4G0 intact:EBI-26499879|ensembl:ENSP00000376397|uniprotkb:Q1EG73|uniprotkb:Q8IX40|uniprotkb:Q8N6D1 intact:EBI-26499879|ensembl:ENSP00000376397|uniprotkb:Q1EG73|uniprotkb:Q8IX40|uniprotkb:Q8N6D1 psi-mi:clm7_human(display_long)|uniprotkb:CD300LB(gene name)|psi-mi:CD300LB(display_short)|uniprotkb:CD300B(gene name synonym)|uniprotkb:CLM7(gene name synonym)|uniprotkb:CMRF35A2(gene name synonym)|uniprotkb:IREM3(gene name synonym)|uniprotkb:LMIR5(gene name synonym)|uniprotkb:TREM5(gene name synonym)|uniprotkb:CD300 antigen-like family member B(gene name synonym)|uniprotkb:CMRF35-A2(gene name synonym)|uniprotkb:Immune receptor expressed on myeloid cells 3(gene name synonym)|uniprotkb:Leukocyte mono-Ig-like receptor 5(gene name synonym)|uniprotkb:Triggering receptor expressed on myeloid cells 5(gene name synonym)|uniprotkb:UNQ2530/PRO6029(orf name) psi-mi:clm7_human(display_long)|uniprotkb:CD300LB(gene name)|psi-mi:CD300LB(display_short)|uniprotkb:CD300B(gene name synonym)|uniprotkb:CLM7(gene name synonym)|uniprotkb:CMRF35A2(gene name synonym)|uniprotkb:IREM3(gene name synonym)|uniprotkb:LMIR5(gene name synonym)|uniprotkb:TREM5(gene name synonym)|uniprotkb:CD300 antigen-like family member B(gene name synonym)|uniprotkb:CMRF35-A2(gene name synonym)|uniprotkb:Immune receptor expressed on myeloid cells 3(gene name synonym)|uniprotkb:Leukocyte mono-Ig-like receptor 5(gene name synonym)|uniprotkb:Triggering receptor expressed on myeloid cells 5(gene name synonym)|uniprotkb:UNQ2530/PRO6029(orf name) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Martínez-Barriocanal et al. (2017) pubmed:29051512|imex:IM-28607 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0486"(UniProt) intact:EBI-26518499|imex:IM-28607-13 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000178789(gene)|ensembl:ENST00000392621(transcript)|go:"GO:0002376"(immune system process)|go:"GO:0004888"(transmembrane signaling receptor activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0042802"(identical protein binding)|interpro:IPR003599(Immunoglobulin subtype)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR013106(Immunoglobulin V-set)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR036179|reactome:R-HSA-198933|reactome:R-HSA-2172127|refseq:NP_777552.3 ensembl:ENSG00000178789(gene)|ensembl:ENST00000392621(transcript)|go:"GO:0002376"(immune system process)|go:"GO:0004888"(transmembrane signaling receptor activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0042802"(identical protein binding)|interpro:IPR003599(Immunoglobulin subtype)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR013106(Immunoglobulin V-set)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR036179|reactome:R-HSA-198933|reactome:R-HSA-2172127|refseq:NP_777552.3 - - - figure legend:Fig. 4|dataset:Rare diseases - Interactions investigated in the context of Rare genetic disease|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9534(chlae-cos_7)|taxid:9534(Cercopithecus aethiops simian cells transformed with SV40) - 2020/12/09 2020/12/09 rogid:CiZcMyJI10I18uugrUsh40aIEUU9606 rogid:CiZcMyJI10I18uugrUsh40aIEUU9606 rigid:8xYPpPjdGZRnS0Hf0MyoppTWslc false ha tag:?-?|mutation with no effect:28-29 flag tag:?-?|mutation with no effect:81-81,84-84,28-29 - - psi-mi:"MI:0705"(anti tag western blot) psi-mi:"MI:0705"(anti tag western blot) uniprotkb:A8K4G0 uniprotkb:A8K4G0 intact:EBI-26499879|ensembl:ENSP00000376397|uniprotkb:Q1EG73|uniprotkb:Q8IX40|uniprotkb:Q8N6D1 intact:EBI-26499879|ensembl:ENSP00000376397|uniprotkb:Q1EG73|uniprotkb:Q8IX40|uniprotkb:Q8N6D1 psi-mi:clm7_human(display_long)|uniprotkb:CD300LB(gene name)|psi-mi:CD300LB(display_short)|uniprotkb:CD300B(gene name synonym)|uniprotkb:CLM7(gene name synonym)|uniprotkb:CMRF35A2(gene name synonym)|uniprotkb:IREM3(gene name synonym)|uniprotkb:LMIR5(gene name synonym)|uniprotkb:TREM5(gene name synonym)|uniprotkb:CD300 antigen-like family member B(gene name synonym)|uniprotkb:CMRF35-A2(gene name synonym)|uniprotkb:Immune receptor expressed on myeloid cells 3(gene name synonym)|uniprotkb:Leukocyte mono-Ig-like receptor 5(gene name synonym)|uniprotkb:Triggering receptor expressed on myeloid cells 5(gene name synonym)|uniprotkb:UNQ2530/PRO6029(orf name) psi-mi:clm7_human(display_long)|uniprotkb:CD300LB(gene name)|psi-mi:CD300LB(display_short)|uniprotkb:CD300B(gene name synonym)|uniprotkb:CLM7(gene name synonym)|uniprotkb:CMRF35A2(gene name synonym)|uniprotkb:IREM3(gene name synonym)|uniprotkb:LMIR5(gene name synonym)|uniprotkb:TREM5(gene name synonym)|uniprotkb:CD300 antigen-like family member B(gene name synonym)|uniprotkb:CMRF35-A2(gene name synonym)|uniprotkb:Immune receptor expressed on myeloid cells 3(gene name synonym)|uniprotkb:Leukocyte mono-Ig-like receptor 5(gene name synonym)|uniprotkb:Triggering receptor expressed on myeloid cells 5(gene name synonym)|uniprotkb:UNQ2530/PRO6029(orf name) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Martínez-Barriocanal et al. (2017) pubmed:29051512|imex:IM-28607 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0486"(UniProt) intact:EBI-26564481|imex:IM-28607-15 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000178789(gene)|ensembl:ENST00000392621(transcript)|go:"GO:0002376"(immune system process)|go:"GO:0004888"(transmembrane signaling receptor activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0042802"(identical protein binding)|interpro:IPR003599(Immunoglobulin subtype)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR013106(Immunoglobulin V-set)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR036179|reactome:R-HSA-198933|reactome:R-HSA-2172127|refseq:NP_777552.3 ensembl:ENSG00000178789(gene)|ensembl:ENST00000392621(transcript)|go:"GO:0002376"(immune system process)|go:"GO:0004888"(transmembrane signaling receptor activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0042802"(identical protein binding)|interpro:IPR003599(Immunoglobulin subtype)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR013106(Immunoglobulin V-set)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR036179|reactome:R-HSA-198933|reactome:R-HSA-2172127|refseq:NP_777552.3 - - - figure legend:Fig. 4|dataset:Rare diseases - Interactions investigated in the context of Rare genetic disease|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9534(chlae-cos_7)|taxid:9534(Cercopithecus aethiops simian cells transformed with SV40) - 2020/12/09 2020/12/14 rogid:CiZcMyJI10I18uugrUsh40aIEUU9606 rogid:CiZcMyJI10I18uugrUsh40aIEUU9606 rigid:8xYPpPjdGZRnS0Hf0MyoppTWslc false ha tag:?-? mutation with no effect:81-81,84-84|flag tag:?-? - - psi-mi:"MI:0705"(anti tag western blot) psi-mi:"MI:0705"(anti tag western blot) uniprotkb:A8K4G0 uniprotkb:A8K4G0 intact:EBI-26499879|ensembl:ENSP00000376397|uniprotkb:Q1EG73|uniprotkb:Q8IX40|uniprotkb:Q8N6D1 intact:EBI-26499879|ensembl:ENSP00000376397|uniprotkb:Q1EG73|uniprotkb:Q8IX40|uniprotkb:Q8N6D1 psi-mi:clm7_human(display_long)|uniprotkb:CD300LB(gene name)|psi-mi:CD300LB(display_short)|uniprotkb:CD300B(gene name synonym)|uniprotkb:CLM7(gene name synonym)|uniprotkb:CMRF35A2(gene name synonym)|uniprotkb:IREM3(gene name synonym)|uniprotkb:LMIR5(gene name synonym)|uniprotkb:TREM5(gene name synonym)|uniprotkb:CD300 antigen-like family member B(gene name synonym)|uniprotkb:CMRF35-A2(gene name synonym)|uniprotkb:Immune receptor expressed on myeloid cells 3(gene name synonym)|uniprotkb:Leukocyte mono-Ig-like receptor 5(gene name synonym)|uniprotkb:Triggering receptor expressed on myeloid cells 5(gene name synonym)|uniprotkb:UNQ2530/PRO6029(orf name) psi-mi:clm7_human(display_long)|uniprotkb:CD300LB(gene name)|psi-mi:CD300LB(display_short)|uniprotkb:CD300B(gene name synonym)|uniprotkb:CLM7(gene name synonym)|uniprotkb:CMRF35A2(gene name synonym)|uniprotkb:IREM3(gene name synonym)|uniprotkb:LMIR5(gene name synonym)|uniprotkb:TREM5(gene name synonym)|uniprotkb:CD300 antigen-like family member B(gene name synonym)|uniprotkb:CMRF35-A2(gene name synonym)|uniprotkb:Immune receptor expressed on myeloid cells 3(gene name synonym)|uniprotkb:Leukocyte mono-Ig-like receptor 5(gene name synonym)|uniprotkb:Triggering receptor expressed on myeloid cells 5(gene name synonym)|uniprotkb:UNQ2530/PRO6029(orf name) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Martínez-Barriocanal et al. (2017) pubmed:29051512|imex:IM-28607 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0486"(UniProt) intact:EBI-26564496|imex:IM-28607-17 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000178789(gene)|ensembl:ENST00000392621(transcript)|go:"GO:0002376"(immune system process)|go:"GO:0004888"(transmembrane signaling receptor activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0042802"(identical protein binding)|interpro:IPR003599(Immunoglobulin subtype)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR013106(Immunoglobulin V-set)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR036179|reactome:R-HSA-198933|reactome:R-HSA-2172127|refseq:NP_777552.3 ensembl:ENSG00000178789(gene)|ensembl:ENST00000392621(transcript)|go:"GO:0002376"(immune system process)|go:"GO:0004888"(transmembrane signaling receptor activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0042802"(identical protein binding)|interpro:IPR003599(Immunoglobulin subtype)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR013106(Immunoglobulin V-set)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR036179|reactome:R-HSA-198933|reactome:R-HSA-2172127|refseq:NP_777552.3 - - - figure legend:Fig. 4|dataset:Rare diseases - Interactions investigated in the context of Rare genetic disease|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9534(chlae-cos_7)|taxid:9534(Cercopithecus aethiops simian cells transformed with SV40) - 2020/12/09 2020/12/14 rogid:CiZcMyJI10I18uugrUsh40aIEUU9606 rogid:CiZcMyJI10I18uugrUsh40aIEUU9606 rigid:8xYPpPjdGZRnS0Hf0MyoppTWslc false ha tag:?-?|mutation with no effect:28-29 flag tag:?-?|mutation decreasing interaction strength:84-84,81-81 - - psi-mi:"MI:0705"(anti tag western blot) psi-mi:"MI:0705"(anti tag western blot) uniprotkb:Q8TDQ1 uniprotkb:Q8TDQ1 intact:EBI-7381492|uniprotkb:Q6UX24|uniprotkb:B2RCL2|uniprotkb:Q7Z7I4|uniprotkb:Q7Z6A6|uniprotkb:C9JDN3|uniprotkb:Q7Z7I5|intact:MINT-8020158|uniprotkb:Q8N6D0|uniprotkb:Q3Y6P0|uniprotkb:Q8NAF5|ensembl:ENSP00000327075 intact:EBI-7381492|uniprotkb:Q6UX24|uniprotkb:B2RCL2|uniprotkb:Q7Z7I4|uniprotkb:Q7Z6A6|uniprotkb:C9JDN3|uniprotkb:Q7Z7I5|intact:MINT-8020158|uniprotkb:Q8N6D0|uniprotkb:Q3Y6P0|uniprotkb:Q8NAF5|ensembl:ENSP00000327075 psi-mi:clm1_human(display_long)|uniprotkb:CD300LF(gene name)|psi-mi:CD300LF(display_short)|uniprotkb:CD300 antigen-like family member F(gene name synonym)|uniprotkb:CD300F(gene name synonym)|uniprotkb:CLM1(gene name synonym)|uniprotkb:IGSF13(gene name synonym)|uniprotkb:IREM1(gene name synonym)|uniprotkb:Immune receptor expressed on myeloid cells 1(gene name synonym)|uniprotkb:Immunoglobulin superfamily member 13(gene name synonym)|uniprotkb:NK inhibitory receptor(gene name synonym)|uniprotkb:NKIR(gene name synonym)|uniprotkb:UNQ3105/PRO10111(orf name) psi-mi:clm1_human(display_long)|uniprotkb:CD300LF(gene name)|psi-mi:CD300LF(display_short)|uniprotkb:CD300 antigen-like family member F(gene name synonym)|uniprotkb:CD300F(gene name synonym)|uniprotkb:CLM1(gene name synonym)|uniprotkb:IGSF13(gene name synonym)|uniprotkb:IREM1(gene name synonym)|uniprotkb:Immune receptor expressed on myeloid cells 1(gene name synonym)|uniprotkb:Immunoglobulin superfamily member 13(gene name synonym)|uniprotkb:NK inhibitory receptor(gene name synonym)|uniprotkb:NKIR(gene name synonym)|uniprotkb:UNQ3105/PRO10111(orf name) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Martínez-Barriocanal et al. (2017) pubmed:29051512|imex:IM-28607 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0486"(UniProt) intact:EBI-26564510|imex:IM-28607-19 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_620587.2|refseq:NP_001276011.1|refseq:NP_001276012.1|refseq:NP_001276013.1|refseq:NP_001276014.1|refseq:NP_001276015.1|refseq:NP_001276016.1|ensembl:ENSG00000186074(gene)|ensembl:ENST00000326165(transcript)|go:"GO:0001786"(phosphatidylserine binding)|go:"GO:0002376"(immune system process)|go:"GO:0004888"(transmembrane signaling receptor activity)|go:"GO:0005136"(interleukin-4 receptor binding)|go:"GO:0005886"(plasma membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0033004"(negative regulation of mast cell activation)|go:"GO:0034125"(negative regulation of MyD88-dependent toll-like receptor signaling pathway)|go:"GO:0035666"(TRIF-dependent toll-like receptor signaling pathway)|go:"GO:0035772"(interleukin-13-mediated signaling pathway)|go:"GO:0042802"(identical protein binding)|go:"GO:0097001"(ceramide binding)|go:"GO:1902216"(positive regulation of interleukin-4-mediated signaling pathway)|go:"GO:2000426"(negative regulation of apoptotic cell clearance)|go:"GO:2000427"(positive regulation of apoptotic cell clearance)|interpro:IPR003599(Immunoglobulin subtype)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR013106(Immunoglobulin V-set)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR036179|rcsb pdb:2NMS|reactome:R-HSA-198933 refseq:NP_620587.2|refseq:NP_001276011.1|refseq:NP_001276012.1|refseq:NP_001276013.1|refseq:NP_001276014.1|refseq:NP_001276015.1|refseq:NP_001276016.1|ensembl:ENSG00000186074(gene)|ensembl:ENST00000326165(transcript)|go:"GO:0001786"(phosphatidylserine binding)|go:"GO:0002376"(immune system process)|go:"GO:0004888"(transmembrane signaling receptor activity)|go:"GO:0005136"(interleukin-4 receptor binding)|go:"GO:0005886"(plasma membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0033004"(negative regulation of mast cell activation)|go:"GO:0034125"(negative regulation of MyD88-dependent toll-like receptor signaling pathway)|go:"GO:0035666"(TRIF-dependent toll-like receptor signaling pathway)|go:"GO:0035772"(interleukin-13-mediated signaling pathway)|go:"GO:0042802"(identical protein binding)|go:"GO:0097001"(ceramide binding)|go:"GO:1902216"(positive regulation of interleukin-4-mediated signaling pathway)|go:"GO:2000426"(negative regulation of apoptotic cell clearance)|go:"GO:2000427"(positive regulation of apoptotic cell clearance)|interpro:IPR003599(Immunoglobulin subtype)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR013106(Immunoglobulin V-set)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR036179|rcsb pdb:2NMS|reactome:R-HSA-198933 - comment:mint comment:mint figure legend:Fig. 5C|dataset:Rare diseases - Interactions investigated in the context of Rare genetic disease|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9534(chlae-cos_7)|taxid:9534(Cercopithecus aethiops simian cells transformed with SV40) - 2020/12/09 2020/12/14 rogid:cRoagmELrMitO+yvNY3O82t8vQY9606 rogid:cRoagmELrMitO+yvNY3O82t8vQY9606 rigid:+v9b8SO7BWuU67FCfOHC/sxT8Rg false ha tag:?-? flag tag:?-?|mutation with no effect:33-33 - - psi-mi:"MI:0705"(anti tag western blot) psi-mi:"MI:0705"(anti tag western blot)