#ID(s) interactor A	ID(s) interactor B	Alt. ID(s) interactor A	Alt. ID(s) interactor B	Alias(es) interactor A	Alias(es) interactor B	Interaction detection method(s)	Publication 1st author(s)	Publication Identifier(s)	Taxid interactor A	Taxid interactor B	Interaction type(s)	Source database(s)	Interaction identifier(s)	Confidence value(s)	Expansion method(s)	Biological role(s) interactor A	Biological role(s) interactor B	Experimental role(s) interactor A	Experimental role(s) interactor B	Type(s) interactor A	Type(s) interactor B	Xref(s) interactor A	Xref(s) interactor B	Interaction Xref(s)	Annotation(s) interactor A	Annotation(s) interactor B	Interaction annotation(s)	Host organism(s)	Interaction parameter(s)	Creation date	Update date	Checksum(s) interactor A	Checksum(s) interactor B	Interaction Checksum(s)	Negative	Feature(s) interactor A	Feature(s) interactor B	Stoichiometry(s) interactor A	Stoichiometry(s) interactor B	Identification method participant A	Identification method participant B
uniprotkb:Q9GZU1	uniprotkb:Q9GZU1	intact:EBI-721209|uniprotkb:Q7Z4F7|uniprotkb:Q9H292|uniprotkb:Q9H4B3|uniprotkb:Q9H4B5|uniprotkb:D6W647|ensembl:ENSP00000264079	intact:EBI-721209|uniprotkb:Q7Z4F7|uniprotkb:Q9H292|uniprotkb:Q9H4B3|uniprotkb:Q9H4B5|uniprotkb:D6W647|ensembl:ENSP00000264079	psi-mi:mcln1_human(display_long)|uniprotkb:Mucolipidin(gene name synonym)|uniprotkb:MG-2(gene name synonym)|uniprotkb:MCOLN1(gene name)|psi-mi:MCOLN1(display_short)|uniprotkb:ML4(gene name synonym)|uniprotkb:Transient receptor potential channel mucolipin 1(gene name synonym)|uniprotkb:MSTP080(orf name)|uniprotkb:TRPML1(gene name synonym)	psi-mi:mcln1_human(display_long)|uniprotkb:Mucolipidin(gene name synonym)|uniprotkb:MG-2(gene name synonym)|uniprotkb:MCOLN1(gene name)|psi-mi:MCOLN1(display_short)|uniprotkb:ML4(gene name synonym)|uniprotkb:Transient receptor potential channel mucolipin 1(gene name synonym)|uniprotkb:MSTP080(orf name)|uniprotkb:TRPML1(gene name synonym)	psi-mi:"MI:0410"(3D electron microscopy)	Schmiege et al. (2017)	pubmed:29019983|imex:IM-28474	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0465"(DIP)	intact:EBI-26372392|wwpdb:5WJ5|emdb:EMD-8840|wwpdb:5WJ9|emdb:EMD-8841|imex:IM-28474-1	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_065394.1|dip:DIP-62090N|ensembl:ENSG00000090674(gene)|ensembl:ENST00000264079(transcript)|go:"GO:0001891"(phagocytic cup)|go:"GO:0002250"(adaptive immune response)|go:"GO:0005261"(cation channel activity)|go:"GO:0005262"(calcium channel activity)|go:"GO:0005381"(iron ion transmembrane transporter activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005764"(lysosome)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005770"(late endosome)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006812"(cation transport)|go:"GO:0008289"(lipid binding)|go:"GO:0010008"(endosome membrane)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030670"(phagocytic vesicle membrane)|go:"GO:0031902"(late endosome membrane)|go:"GO:0033572"(transferrin transport)|go:"GO:0042802"(identical protein binding)|go:"GO:0042995"(cell projection)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0043235"(receptor complex)|go:"GO:0051289"(protein homotetramerization)|go:"GO:0070588"(calcium ion transmembrane transport)|go:"GO:0071277"(cellular response to calcium ion)|go:"GO:0071467"(cellular response to pH)|go:"GO:0072345"(NAADP-sensitive calcium-release channel activity)|go:"GO:0090382"(phagosome maturation)|go:"GO:0097352"(autophagosome maturation)|go:"GO:0097682"(intracellular phosphatidylinositol-3,5-bisphosphate-sensitive cation channel activity)|go:"GO:0099604"(ligand-gated calcium channel activity)|interpro:IPR013122(Polycystin cation channel, PKD1/PKD2)|interpro:IPR039031|rcsb pdb:5TJA|rcsb pdb:5TJB|rcsb pdb:5TJC|rcsb pdb:5WJ5|rcsb pdb:5WJ9|rcsb pdb:6E7P|rcsb pdb:6E7Y|rcsb pdb:6E7Z|rcsb pdb:7MGL|reactome:R-HSA-3295583|reactome:R-HSA-917977	refseq:NP_065394.1|dip:DIP-62090N|ensembl:ENSG00000090674(gene)|ensembl:ENST00000264079(transcript)|go:"GO:0001891"(phagocytic cup)|go:"GO:0002250"(adaptive immune response)|go:"GO:0005261"(cation channel activity)|go:"GO:0005262"(calcium channel activity)|go:"GO:0005381"(iron ion transmembrane transporter activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005764"(lysosome)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005770"(late endosome)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006812"(cation transport)|go:"GO:0008289"(lipid binding)|go:"GO:0010008"(endosome membrane)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030670"(phagocytic vesicle membrane)|go:"GO:0031902"(late endosome membrane)|go:"GO:0033572"(transferrin transport)|go:"GO:0042802"(identical protein binding)|go:"GO:0042995"(cell projection)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0043235"(receptor complex)|go:"GO:0051289"(protein homotetramerization)|go:"GO:0070588"(calcium ion transmembrane transport)|go:"GO:0071277"(cellular response to calcium ion)|go:"GO:0071467"(cellular response to pH)|go:"GO:0072345"(NAADP-sensitive calcium-release channel activity)|go:"GO:0090382"(phagosome maturation)|go:"GO:0097352"(autophagosome maturation)|go:"GO:0097682"(intracellular phosphatidylinositol-3,5-bisphosphate-sensitive cation channel activity)|go:"GO:0099604"(ligand-gated calcium channel activity)|interpro:IPR013122(Polycystin cation channel, PKD1/PKD2)|interpro:IPR039031|rcsb pdb:5TJA|rcsb pdb:5TJB|rcsb pdb:5TJC|rcsb pdb:5WJ5|rcsb pdb:5WJ9|rcsb pdb:6E7P|rcsb pdb:6E7Y|rcsb pdb:6E7Z|rcsb pdb:7MGL|reactome:R-HSA-3295583|reactome:R-HSA-917977	-	-	-	figure legend:Fig 1, Extended Data Fig 3, Extended Data Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human)|taxid:9606(Homo sapiens)	-	2020/10/17	2020/10/17	rogid:ugaI0/RxbmT8qM9YPN4ZmZTdfCM9606	rogid:ugaI0/RxbmT8qM9YPN4ZmZTdfCM9606	rigid:DD2tqS6j6960tcQxNPCxgQ0Pryo	false	-	-	4	0	psi-mi:"MI:0396"(predetermined participant)|psi-mi:"MI:2287"(identification by structure determination)	psi-mi:"MI:0396"(predetermined participant)|psi-mi:"MI:2287"(identification by structure determination)
uniprotkb:Q9GZU1	uniprotkb:Q9GZU1	intact:EBI-721209|uniprotkb:Q7Z4F7|uniprotkb:Q9H292|uniprotkb:Q9H4B3|uniprotkb:Q9H4B5|uniprotkb:D6W647|ensembl:ENSP00000264079	intact:EBI-721209|uniprotkb:Q7Z4F7|uniprotkb:Q9H292|uniprotkb:Q9H4B3|uniprotkb:Q9H4B5|uniprotkb:D6W647|ensembl:ENSP00000264079	psi-mi:mcln1_human(display_long)|uniprotkb:Mucolipidin(gene name synonym)|uniprotkb:MG-2(gene name synonym)|uniprotkb:MCOLN1(gene name)|psi-mi:MCOLN1(display_short)|uniprotkb:ML4(gene name synonym)|uniprotkb:Transient receptor potential channel mucolipin 1(gene name synonym)|uniprotkb:MSTP080(orf name)|uniprotkb:TRPML1(gene name synonym)	psi-mi:mcln1_human(display_long)|uniprotkb:Mucolipidin(gene name synonym)|uniprotkb:MG-2(gene name synonym)|uniprotkb:MCOLN1(gene name)|psi-mi:MCOLN1(display_short)|uniprotkb:ML4(gene name synonym)|uniprotkb:Transient receptor potential channel mucolipin 1(gene name synonym)|uniprotkb:MSTP080(orf name)|uniprotkb:TRPML1(gene name synonym)	psi-mi:"MI:0071"(molecular sieving)	Schmiege et al. (2017)	pubmed:29019983|imex:IM-28474	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0465"(DIP)	intact:EBI-26372406|imex:IM-28474-3	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_065394.1|dip:DIP-62090N|ensembl:ENSG00000090674(gene)|ensembl:ENST00000264079(transcript)|go:"GO:0001891"(phagocytic cup)|go:"GO:0002250"(adaptive immune response)|go:"GO:0005261"(cation channel activity)|go:"GO:0005262"(calcium channel activity)|go:"GO:0005381"(iron ion transmembrane transporter activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005764"(lysosome)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005770"(late endosome)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006812"(cation transport)|go:"GO:0008289"(lipid binding)|go:"GO:0010008"(endosome membrane)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030670"(phagocytic vesicle membrane)|go:"GO:0031902"(late endosome membrane)|go:"GO:0033572"(transferrin transport)|go:"GO:0042802"(identical protein binding)|go:"GO:0042995"(cell projection)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0043235"(receptor complex)|go:"GO:0051289"(protein homotetramerization)|go:"GO:0070588"(calcium ion transmembrane transport)|go:"GO:0071277"(cellular response to calcium ion)|go:"GO:0071467"(cellular response to pH)|go:"GO:0072345"(NAADP-sensitive calcium-release channel activity)|go:"GO:0090382"(phagosome maturation)|go:"GO:0097352"(autophagosome maturation)|go:"GO:0097682"(intracellular phosphatidylinositol-3,5-bisphosphate-sensitive cation channel activity)|go:"GO:0099604"(ligand-gated calcium channel activity)|interpro:IPR013122(Polycystin cation channel, PKD1/PKD2)|interpro:IPR039031|rcsb pdb:5TJA|rcsb pdb:5TJB|rcsb pdb:5TJC|rcsb pdb:5WJ5|rcsb pdb:5WJ9|rcsb pdb:6E7P|rcsb pdb:6E7Y|rcsb pdb:6E7Z|rcsb pdb:7MGL|reactome:R-HSA-3295583|reactome:R-HSA-917977	refseq:NP_065394.1|dip:DIP-62090N|ensembl:ENSG00000090674(gene)|ensembl:ENST00000264079(transcript)|go:"GO:0001891"(phagocytic cup)|go:"GO:0002250"(adaptive immune response)|go:"GO:0005261"(cation channel activity)|go:"GO:0005262"(calcium channel activity)|go:"GO:0005381"(iron ion transmembrane transporter activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005764"(lysosome)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005770"(late endosome)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006812"(cation transport)|go:"GO:0008289"(lipid binding)|go:"GO:0010008"(endosome membrane)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030670"(phagocytic vesicle membrane)|go:"GO:0031902"(late endosome membrane)|go:"GO:0033572"(transferrin transport)|go:"GO:0042802"(identical protein binding)|go:"GO:0042995"(cell projection)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0043235"(receptor complex)|go:"GO:0051289"(protein homotetramerization)|go:"GO:0070588"(calcium ion transmembrane transport)|go:"GO:0071277"(cellular response to calcium ion)|go:"GO:0071467"(cellular response to pH)|go:"GO:0072345"(NAADP-sensitive calcium-release channel activity)|go:"GO:0090382"(phagosome maturation)|go:"GO:0097352"(autophagosome maturation)|go:"GO:0097682"(intracellular phosphatidylinositol-3,5-bisphosphate-sensitive cation channel activity)|go:"GO:0099604"(ligand-gated calcium channel activity)|interpro:IPR013122(Polycystin cation channel, PKD1/PKD2)|interpro:IPR039031|rcsb pdb:5TJA|rcsb pdb:5TJB|rcsb pdb:5TJC|rcsb pdb:5WJ5|rcsb pdb:5WJ9|rcsb pdb:6E7P|rcsb pdb:6E7Y|rcsb pdb:6E7Z|rcsb pdb:7MGL|reactome:R-HSA-3295583|reactome:R-HSA-917977	-	-	-	figure legend:Extended Data Fig 2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human)|taxid:9606(Homo sapiens)	-	2020/10/17	2020/10/17	rogid:ugaI0/RxbmT8qM9YPN4ZmZTdfCM9606	rogid:ugaI0/RxbmT8qM9YPN4ZmZTdfCM9606	rigid:DD2tqS6j6960tcQxNPCxgQ0Pryo	false	-	-	4	0	psi-mi:"MI:0396"(predetermined participant)|psi-mi:"MI:2287"(identification by structure determination)	psi-mi:"MI:0396"(predetermined participant)|psi-mi:"MI:2287"(identification by structure determination)