#ID(s) interactor A	ID(s) interactor B	Alt. ID(s) interactor A	Alt. ID(s) interactor B	Alias(es) interactor A	Alias(es) interactor B	Interaction detection method(s)	Publication 1st author(s)	Publication Identifier(s)	Taxid interactor A	Taxid interactor B	Interaction type(s)	Source database(s)	Interaction identifier(s)	Confidence value(s)	Expansion method(s)	Biological role(s) interactor A	Biological role(s) interactor B	Experimental role(s) interactor A	Experimental role(s) interactor B	Type(s) interactor A	Type(s) interactor B	Xref(s) interactor A	Xref(s) interactor B	Interaction Xref(s)	Annotation(s) interactor A	Annotation(s) interactor B	Interaction annotation(s)	Host organism(s)	Interaction parameter(s)	Creation date	Update date	Checksum(s) interactor A	Checksum(s) interactor B	Interaction Checksum(s)	Negative	Feature(s) interactor A	Feature(s) interactor B	Stoichiometry(s) interactor A	Stoichiometry(s) interactor B	Identification method participant A	Identification method participant B
uniprotkb:F6RG56	uniprotkb:F6RG56	intact:EBI-26372251|ensembl:ENSCJAP00000012762	intact:EBI-26372251|ensembl:ENSCJAP00000012762	psi-mi:mcln3_calja(display_long)|uniprotkb:MCOLN3(gene name)|psi-mi:MCOLN3(display_short)|uniprotkb:Transient receptor potential channel mucolipin 3(gene name synonym)	psi-mi:mcln3_calja(display_long)|uniprotkb:MCOLN3(gene name)|psi-mi:MCOLN3(display_short)|uniprotkb:Transient receptor potential channel mucolipin 3(gene name synonym)	psi-mi:"MI:0410"(3D electron microscopy)	Hirschi et al. (2017)	pubmed:29019979|imex:IM-28635	taxid:9483(calja)|taxid:9483("Callithrix jacchus (White-tufted-ear marmoset)")	taxid:9483(calja)|taxid:9483("Callithrix jacchus (White-tufted-ear marmoset)")	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0465"(DIP)	intact:EBI-26372248|wwpdb:5W3S|emdb:EMD-8764|imex:IM-28635-1	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSCJAG00000006859(gene)|ensembl:ENSCJAT00000013447(transcript)|go:"GO:0000421"(autophagosome membrane)|go:"GO:0007626"(locomotory behavior)|go:"GO:0016021"(integral component of membrane)|go:"GO:0031901"(early endosome membrane)|go:"GO:0031902"(late endosome membrane)|go:"GO:0042491"(inner ear auditory receptor cell differentiation)|go:"GO:0051289"(protein homotetramerization)|go:"GO:0060171"(stereocilium membrane)|go:"GO:0080025"(phosphatidylinositol-3,5-bisphosphate binding)|go:"GO:0097682"(intracellular phosphatidylinositol-3,5-bisphosphate-sensitive cation channel activity)|go:"GO:0098655"(cation transmembrane transport)|go:"GO:1905103"(integral component of lysosomal membrane)|interpro:IPR013122(Polycystin cation channel, PKD1/PKD2)|interpro:IPR039031|rcsb pdb:5W3S|go:"GO:0042802"(identical protein binding)|refseq:XP_002751067.1|refseq:XP_008999856.1	ensembl:ENSCJAG00000006859(gene)|ensembl:ENSCJAT00000013447(transcript)|go:"GO:0000421"(autophagosome membrane)|go:"GO:0007626"(locomotory behavior)|go:"GO:0016021"(integral component of membrane)|go:"GO:0031901"(early endosome membrane)|go:"GO:0031902"(late endosome membrane)|go:"GO:0042491"(inner ear auditory receptor cell differentiation)|go:"GO:0051289"(protein homotetramerization)|go:"GO:0060171"(stereocilium membrane)|go:"GO:0080025"(phosphatidylinositol-3,5-bisphosphate binding)|go:"GO:0097682"(intracellular phosphatidylinositol-3,5-bisphosphate-sensitive cation channel activity)|go:"GO:0098655"(cation transmembrane transport)|go:"GO:1905103"(integral component of lysosomal membrane)|interpro:IPR013122(Polycystin cation channel, PKD1/PKD2)|interpro:IPR039031|rcsb pdb:5W3S|go:"GO:0042802"(identical protein binding)|refseq:XP_002751067.1|refseq:XP_008999856.1	-	-	-	figure legend:Fig 1, Extended Data Fig 3, Extended Data Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:7108(spofr-sf_9)|taxid:7108(Spodoptera frugiperda insect cells)	-	2020/10/16	2020/10/16	rogid:W2z/IDdxYUNs680IkN6C/LSl+0E9483	rogid:W2z/IDdxYUNs680IkN6C/LSl+0E9483	rigid:+h5DExFTxBMbTABvaGz7Up++b5o	false	mutation:138-138|binding-associated region:1-553	mutation:138-138|binding-associated region:1-553	4	0	psi-mi:"MI:0396"(predetermined participant)|psi-mi:"MI:2287"(identification by structure determination)	psi-mi:"MI:0396"(predetermined participant)|psi-mi:"MI:2287"(identification by structure determination)
uniprotkb:F6RG56	uniprotkb:F6RG56	intact:EBI-26372251|ensembl:ENSCJAP00000012762	intact:EBI-26372251|ensembl:ENSCJAP00000012762	psi-mi:mcln3_calja(display_long)|uniprotkb:MCOLN3(gene name)|psi-mi:MCOLN3(display_short)|uniprotkb:Transient receptor potential channel mucolipin 3(gene name synonym)	psi-mi:mcln3_calja(display_long)|uniprotkb:MCOLN3(gene name)|psi-mi:MCOLN3(display_short)|uniprotkb:Transient receptor potential channel mucolipin 3(gene name synonym)	psi-mi:"MI:0065"(isothermal titration calorimetry)	Hirschi et al. (2017)	pubmed:29019979|imex:IM-28635	taxid:9483(calja)|taxid:9483("Callithrix jacchus (White-tufted-ear marmoset)")	taxid:9483(calja)|taxid:9483("Callithrix jacchus (White-tufted-ear marmoset)")	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0465"(DIP)	intact:EBI-26372289|imex:IM-28635-3	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSCJAG00000006859(gene)|ensembl:ENSCJAT00000013447(transcript)|go:"GO:0000421"(autophagosome membrane)|go:"GO:0007626"(locomotory behavior)|go:"GO:0016021"(integral component of membrane)|go:"GO:0031901"(early endosome membrane)|go:"GO:0031902"(late endosome membrane)|go:"GO:0042491"(inner ear auditory receptor cell differentiation)|go:"GO:0051289"(protein homotetramerization)|go:"GO:0060171"(stereocilium membrane)|go:"GO:0080025"(phosphatidylinositol-3,5-bisphosphate binding)|go:"GO:0097682"(intracellular phosphatidylinositol-3,5-bisphosphate-sensitive cation channel activity)|go:"GO:0098655"(cation transmembrane transport)|go:"GO:1905103"(integral component of lysosomal membrane)|interpro:IPR013122(Polycystin cation channel, PKD1/PKD2)|interpro:IPR039031|rcsb pdb:5W3S|go:"GO:0042802"(identical protein binding)|refseq:XP_002751067.1|refseq:XP_008999856.1	ensembl:ENSCJAG00000006859(gene)|ensembl:ENSCJAT00000013447(transcript)|go:"GO:0000421"(autophagosome membrane)|go:"GO:0007626"(locomotory behavior)|go:"GO:0016021"(integral component of membrane)|go:"GO:0031901"(early endosome membrane)|go:"GO:0031902"(late endosome membrane)|go:"GO:0042491"(inner ear auditory receptor cell differentiation)|go:"GO:0051289"(protein homotetramerization)|go:"GO:0060171"(stereocilium membrane)|go:"GO:0080025"(phosphatidylinositol-3,5-bisphosphate binding)|go:"GO:0097682"(intracellular phosphatidylinositol-3,5-bisphosphate-sensitive cation channel activity)|go:"GO:0098655"(cation transmembrane transport)|go:"GO:1905103"(integral component of lysosomal membrane)|interpro:IPR013122(Polycystin cation channel, PKD1/PKD2)|interpro:IPR039031|rcsb pdb:5W3S|go:"GO:0042802"(identical protein binding)|refseq:XP_002751067.1|refseq:XP_008999856.1	-	-	-	figure legend:Extended Data Fig 2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:7108(spofr-sf_9)|taxid:7108(Spodoptera frugiperda insect cells)	-	2020/10/16	2020/10/16	rogid:W2z/IDdxYUNs680IkN6C/LSl+0E9483	rogid:W2z/IDdxYUNs680IkN6C/LSl+0E9483	rigid:+h5DExFTxBMbTABvaGz7Up++b5o	false	mutation:138-138|binding-associated region:1-553	mutation:138-138|binding-associated region:1-553	4	0	psi-mi:"MI:0396"(predetermined participant)|psi-mi:"MI:2287"(identification by structure determination)	psi-mi:"MI:0396"(predetermined participant)|psi-mi:"MI:2287"(identification by structure determination)
uniprotkb:F6RG56	uniprotkb:F6RG56	intact:EBI-26372251|ensembl:ENSCJAP00000012762	intact:EBI-26372251|ensembl:ENSCJAP00000012762	psi-mi:mcln3_calja(display_long)|uniprotkb:MCOLN3(gene name)|psi-mi:MCOLN3(display_short)|uniprotkb:Transient receptor potential channel mucolipin 3(gene name synonym)	psi-mi:mcln3_calja(display_long)|uniprotkb:MCOLN3(gene name)|psi-mi:MCOLN3(display_short)|uniprotkb:Transient receptor potential channel mucolipin 3(gene name synonym)	psi-mi:"MI:0065"(isothermal titration calorimetry)	Hirschi et al. (2017)	pubmed:29019979|imex:IM-28635	taxid:9483(calja)|taxid:9483("Callithrix jacchus (White-tufted-ear marmoset)")	taxid:9483(calja)|taxid:9483("Callithrix jacchus (White-tufted-ear marmoset)")	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0465"(DIP)	intact:EBI-26568545|imex:IM-28635-5	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSCJAG00000006859(gene)|ensembl:ENSCJAT00000013447(transcript)|go:"GO:0000421"(autophagosome membrane)|go:"GO:0007626"(locomotory behavior)|go:"GO:0016021"(integral component of membrane)|go:"GO:0031901"(early endosome membrane)|go:"GO:0031902"(late endosome membrane)|go:"GO:0042491"(inner ear auditory receptor cell differentiation)|go:"GO:0051289"(protein homotetramerization)|go:"GO:0060171"(stereocilium membrane)|go:"GO:0080025"(phosphatidylinositol-3,5-bisphosphate binding)|go:"GO:0097682"(intracellular phosphatidylinositol-3,5-bisphosphate-sensitive cation channel activity)|go:"GO:0098655"(cation transmembrane transport)|go:"GO:1905103"(integral component of lysosomal membrane)|interpro:IPR013122(Polycystin cation channel, PKD1/PKD2)|interpro:IPR039031|rcsb pdb:5W3S|go:"GO:0042802"(identical protein binding)|refseq:XP_002751067.1|refseq:XP_008999856.1	ensembl:ENSCJAG00000006859(gene)|ensembl:ENSCJAT00000013447(transcript)|go:"GO:0000421"(autophagosome membrane)|go:"GO:0007626"(locomotory behavior)|go:"GO:0016021"(integral component of membrane)|go:"GO:0031901"(early endosome membrane)|go:"GO:0031902"(late endosome membrane)|go:"GO:0042491"(inner ear auditory receptor cell differentiation)|go:"GO:0051289"(protein homotetramerization)|go:"GO:0060171"(stereocilium membrane)|go:"GO:0080025"(phosphatidylinositol-3,5-bisphosphate binding)|go:"GO:0097682"(intracellular phosphatidylinositol-3,5-bisphosphate-sensitive cation channel activity)|go:"GO:0098655"(cation transmembrane transport)|go:"GO:1905103"(integral component of lysosomal membrane)|interpro:IPR013122(Polycystin cation channel, PKD1/PKD2)|interpro:IPR039031|rcsb pdb:5W3S|go:"GO:0042802"(identical protein binding)|refseq:XP_002751067.1|refseq:XP_008999856.1	-	-	-	figure legend:Extended Data Fig 2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:7108(spofr-sf_9)|taxid:7108(Spodoptera frugiperda insect cells)	-	2020/10/16	2020/12/23	rogid:W2z/IDdxYUNs680IkN6C/LSl+0E9483	rogid:W2z/IDdxYUNs680IkN6C/LSl+0E9483	rigid:+h5DExFTxBMbTABvaGz7Up++b5o	false	mutation:58-58|binding-associated region:1-553	mutation:58-58|binding-associated region:1-553	4	0	psi-mi:"MI:2287"(identification by structure determination)	psi-mi:"MI:2287"(identification by structure determination)
uniprotkb:F6RG56	uniprotkb:F6RG56	intact:EBI-26372251|ensembl:ENSCJAP00000012762	intact:EBI-26372251|ensembl:ENSCJAP00000012762	psi-mi:mcln3_calja(display_long)|uniprotkb:MCOLN3(gene name)|psi-mi:MCOLN3(display_short)|uniprotkb:Transient receptor potential channel mucolipin 3(gene name synonym)	psi-mi:mcln3_calja(display_long)|uniprotkb:MCOLN3(gene name)|psi-mi:MCOLN3(display_short)|uniprotkb:Transient receptor potential channel mucolipin 3(gene name synonym)	psi-mi:"MI:0065"(isothermal titration calorimetry)	Hirschi et al. (2017)	pubmed:29019979|imex:IM-28635	taxid:9483(calja)|taxid:9483("Callithrix jacchus (White-tufted-ear marmoset)")	taxid:9483(calja)|taxid:9483("Callithrix jacchus (White-tufted-ear marmoset)")	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0465"(DIP)	intact:EBI-26568553|imex:IM-28635-7	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSCJAG00000006859(gene)|ensembl:ENSCJAT00000013447(transcript)|go:"GO:0000421"(autophagosome membrane)|go:"GO:0007626"(locomotory behavior)|go:"GO:0016021"(integral component of membrane)|go:"GO:0031901"(early endosome membrane)|go:"GO:0031902"(late endosome membrane)|go:"GO:0042491"(inner ear auditory receptor cell differentiation)|go:"GO:0051289"(protein homotetramerization)|go:"GO:0060171"(stereocilium membrane)|go:"GO:0080025"(phosphatidylinositol-3,5-bisphosphate binding)|go:"GO:0097682"(intracellular phosphatidylinositol-3,5-bisphosphate-sensitive cation channel activity)|go:"GO:0098655"(cation transmembrane transport)|go:"GO:1905103"(integral component of lysosomal membrane)|interpro:IPR013122(Polycystin cation channel, PKD1/PKD2)|interpro:IPR039031|rcsb pdb:5W3S|go:"GO:0042802"(identical protein binding)|refseq:XP_002751067.1|refseq:XP_008999856.1	ensembl:ENSCJAG00000006859(gene)|ensembl:ENSCJAT00000013447(transcript)|go:"GO:0000421"(autophagosome membrane)|go:"GO:0007626"(locomotory behavior)|go:"GO:0016021"(integral component of membrane)|go:"GO:0031901"(early endosome membrane)|go:"GO:0031902"(late endosome membrane)|go:"GO:0042491"(inner ear auditory receptor cell differentiation)|go:"GO:0051289"(protein homotetramerization)|go:"GO:0060171"(stereocilium membrane)|go:"GO:0080025"(phosphatidylinositol-3,5-bisphosphate binding)|go:"GO:0097682"(intracellular phosphatidylinositol-3,5-bisphosphate-sensitive cation channel activity)|go:"GO:0098655"(cation transmembrane transport)|go:"GO:1905103"(integral component of lysosomal membrane)|interpro:IPR013122(Polycystin cation channel, PKD1/PKD2)|interpro:IPR039031|rcsb pdb:5W3S|go:"GO:0042802"(identical protein binding)|refseq:XP_002751067.1|refseq:XP_008999856.1	-	-	-	figure legend:Extended Data Fig 2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:7108(spofr-sf_9)|taxid:7108(Spodoptera frugiperda insect cells)	-	2020/10/16	2020/12/23	rogid:W2z/IDdxYUNs680IkN6C/LSl+0E9483	rogid:W2z/IDdxYUNs680IkN6C/LSl+0E9483	rigid:+h5DExFTxBMbTABvaGz7Up++b5o	false	mutation:62-62|binding-associated region:1-553	mutation:62-62|binding-associated region:1-553	4	0	psi-mi:"MI:2287"(identification by structure determination)	psi-mi:"MI:2287"(identification by structure determination)
uniprotkb:F6RG56	uniprotkb:F6RG56	intact:EBI-26372251|ensembl:ENSCJAP00000012762	intact:EBI-26372251|ensembl:ENSCJAP00000012762	psi-mi:mcln3_calja(display_long)|uniprotkb:MCOLN3(gene name)|psi-mi:MCOLN3(display_short)|uniprotkb:Transient receptor potential channel mucolipin 3(gene name synonym)	psi-mi:mcln3_calja(display_long)|uniprotkb:MCOLN3(gene name)|psi-mi:MCOLN3(display_short)|uniprotkb:Transient receptor potential channel mucolipin 3(gene name synonym)	psi-mi:"MI:0065"(isothermal titration calorimetry)	Hirschi et al. (2017)	pubmed:29019979|imex:IM-28635	taxid:9483(calja)|taxid:9483("Callithrix jacchus (White-tufted-ear marmoset)")	taxid:9483(calja)|taxid:9483("Callithrix jacchus (White-tufted-ear marmoset)")	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0465"(DIP)	intact:EBI-26568561|imex:IM-28635-9	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSCJAG00000006859(gene)|ensembl:ENSCJAT00000013447(transcript)|go:"GO:0000421"(autophagosome membrane)|go:"GO:0007626"(locomotory behavior)|go:"GO:0016021"(integral component of membrane)|go:"GO:0031901"(early endosome membrane)|go:"GO:0031902"(late endosome membrane)|go:"GO:0042491"(inner ear auditory receptor cell differentiation)|go:"GO:0051289"(protein homotetramerization)|go:"GO:0060171"(stereocilium membrane)|go:"GO:0080025"(phosphatidylinositol-3,5-bisphosphate binding)|go:"GO:0097682"(intracellular phosphatidylinositol-3,5-bisphosphate-sensitive cation channel activity)|go:"GO:0098655"(cation transmembrane transport)|go:"GO:1905103"(integral component of lysosomal membrane)|interpro:IPR013122(Polycystin cation channel, PKD1/PKD2)|interpro:IPR039031|rcsb pdb:5W3S|go:"GO:0042802"(identical protein binding)|refseq:XP_002751067.1|refseq:XP_008999856.1	ensembl:ENSCJAG00000006859(gene)|ensembl:ENSCJAT00000013447(transcript)|go:"GO:0000421"(autophagosome membrane)|go:"GO:0007626"(locomotory behavior)|go:"GO:0016021"(integral component of membrane)|go:"GO:0031901"(early endosome membrane)|go:"GO:0031902"(late endosome membrane)|go:"GO:0042491"(inner ear auditory receptor cell differentiation)|go:"GO:0051289"(protein homotetramerization)|go:"GO:0060171"(stereocilium membrane)|go:"GO:0080025"(phosphatidylinositol-3,5-bisphosphate binding)|go:"GO:0097682"(intracellular phosphatidylinositol-3,5-bisphosphate-sensitive cation channel activity)|go:"GO:0098655"(cation transmembrane transport)|go:"GO:1905103"(integral component of lysosomal membrane)|interpro:IPR013122(Polycystin cation channel, PKD1/PKD2)|interpro:IPR039031|rcsb pdb:5W3S|go:"GO:0042802"(identical protein binding)|refseq:XP_002751067.1|refseq:XP_008999856.1	-	-	-	figure legend:Extended Data Fig 2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:7108(spofr-sf_9)|taxid:7108(Spodoptera frugiperda insect cells)	-	2020/10/16	2020/12/23	rogid:W2z/IDdxYUNs680IkN6C/LSl+0E9483	rogid:W2z/IDdxYUNs680IkN6C/LSl+0E9483	rigid:+h5DExFTxBMbTABvaGz7Up++b5o	false	mutation:342-342|binding-associated region:1-553	mutation:342-342|binding-associated region:1-553	4	0	psi-mi:"MI:2287"(identification by structure determination)	psi-mi:"MI:2287"(identification by structure determination)
uniprotkb:F6RG56	uniprotkb:F6RG56	intact:EBI-26372251|ensembl:ENSCJAP00000012762	intact:EBI-26372251|ensembl:ENSCJAP00000012762	psi-mi:mcln3_calja(display_long)|uniprotkb:MCOLN3(gene name)|psi-mi:MCOLN3(display_short)|uniprotkb:Transient receptor potential channel mucolipin 3(gene name synonym)	psi-mi:mcln3_calja(display_long)|uniprotkb:MCOLN3(gene name)|psi-mi:MCOLN3(display_short)|uniprotkb:Transient receptor potential channel mucolipin 3(gene name synonym)	psi-mi:"MI:0065"(isothermal titration calorimetry)	Hirschi et al. (2017)	pubmed:29019979|imex:IM-28635	taxid:9483(calja)|taxid:9483("Callithrix jacchus (White-tufted-ear marmoset)")	taxid:9483(calja)|taxid:9483("Callithrix jacchus (White-tufted-ear marmoset)")	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0465"(DIP)	intact:EBI-26568569|imex:IM-28635-11	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSCJAG00000006859(gene)|ensembl:ENSCJAT00000013447(transcript)|go:"GO:0000421"(autophagosome membrane)|go:"GO:0007626"(locomotory behavior)|go:"GO:0016021"(integral component of membrane)|go:"GO:0031901"(early endosome membrane)|go:"GO:0031902"(late endosome membrane)|go:"GO:0042491"(inner ear auditory receptor cell differentiation)|go:"GO:0051289"(protein homotetramerization)|go:"GO:0060171"(stereocilium membrane)|go:"GO:0080025"(phosphatidylinositol-3,5-bisphosphate binding)|go:"GO:0097682"(intracellular phosphatidylinositol-3,5-bisphosphate-sensitive cation channel activity)|go:"GO:0098655"(cation transmembrane transport)|go:"GO:1905103"(integral component of lysosomal membrane)|interpro:IPR013122(Polycystin cation channel, PKD1/PKD2)|interpro:IPR039031|rcsb pdb:5W3S|go:"GO:0042802"(identical protein binding)|refseq:XP_002751067.1|refseq:XP_008999856.1	ensembl:ENSCJAG00000006859(gene)|ensembl:ENSCJAT00000013447(transcript)|go:"GO:0000421"(autophagosome membrane)|go:"GO:0007626"(locomotory behavior)|go:"GO:0016021"(integral component of membrane)|go:"GO:0031901"(early endosome membrane)|go:"GO:0031902"(late endosome membrane)|go:"GO:0042491"(inner ear auditory receptor cell differentiation)|go:"GO:0051289"(protein homotetramerization)|go:"GO:0060171"(stereocilium membrane)|go:"GO:0080025"(phosphatidylinositol-3,5-bisphosphate binding)|go:"GO:0097682"(intracellular phosphatidylinositol-3,5-bisphosphate-sensitive cation channel activity)|go:"GO:0098655"(cation transmembrane transport)|go:"GO:1905103"(integral component of lysosomal membrane)|interpro:IPR013122(Polycystin cation channel, PKD1/PKD2)|interpro:IPR039031|rcsb pdb:5W3S|go:"GO:0042802"(identical protein binding)|refseq:XP_002751067.1|refseq:XP_008999856.1	-	-	-	figure legend:Extended Data Fig 2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:7108(spofr-sf_9)|taxid:7108(Spodoptera frugiperda insect cells)	-	2020/10/16	2020/12/23	rogid:W2z/IDdxYUNs680IkN6C/LSl+0E9483	rogid:W2z/IDdxYUNs680IkN6C/LSl+0E9483	rigid:+h5DExFTxBMbTABvaGz7Up++b5o	false	mutation:305-305|binding-associated region:1-553	mutation:305-305|binding-associated region:1-553	4	0	psi-mi:"MI:2287"(identification by structure determination)	psi-mi:"MI:2287"(identification by structure determination)
uniprotkb:F6RG56	uniprotkb:F6RG56	intact:EBI-26372251|ensembl:ENSCJAP00000012762	intact:EBI-26372251|ensembl:ENSCJAP00000012762	psi-mi:mcln3_calja(display_long)|uniprotkb:MCOLN3(gene name)|psi-mi:MCOLN3(display_short)|uniprotkb:Transient receptor potential channel mucolipin 3(gene name synonym)	psi-mi:mcln3_calja(display_long)|uniprotkb:MCOLN3(gene name)|psi-mi:MCOLN3(display_short)|uniprotkb:Transient receptor potential channel mucolipin 3(gene name synonym)	psi-mi:"MI:0065"(isothermal titration calorimetry)	Hirschi et al. (2017)	pubmed:29019979|imex:IM-28635	taxid:9483(calja)|taxid:9483("Callithrix jacchus (White-tufted-ear marmoset)")	taxid:9483(calja)|taxid:9483("Callithrix jacchus (White-tufted-ear marmoset)")	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0465"(DIP)	intact:EBI-26568577|imex:IM-28635-13	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSCJAG00000006859(gene)|ensembl:ENSCJAT00000013447(transcript)|go:"GO:0000421"(autophagosome membrane)|go:"GO:0007626"(locomotory behavior)|go:"GO:0016021"(integral component of membrane)|go:"GO:0031901"(early endosome membrane)|go:"GO:0031902"(late endosome membrane)|go:"GO:0042491"(inner ear auditory receptor cell differentiation)|go:"GO:0051289"(protein homotetramerization)|go:"GO:0060171"(stereocilium membrane)|go:"GO:0080025"(phosphatidylinositol-3,5-bisphosphate binding)|go:"GO:0097682"(intracellular phosphatidylinositol-3,5-bisphosphate-sensitive cation channel activity)|go:"GO:0098655"(cation transmembrane transport)|go:"GO:1905103"(integral component of lysosomal membrane)|interpro:IPR013122(Polycystin cation channel, PKD1/PKD2)|interpro:IPR039031|rcsb pdb:5W3S|go:"GO:0042802"(identical protein binding)|refseq:XP_002751067.1|refseq:XP_008999856.1	ensembl:ENSCJAG00000006859(gene)|ensembl:ENSCJAT00000013447(transcript)|go:"GO:0000421"(autophagosome membrane)|go:"GO:0007626"(locomotory behavior)|go:"GO:0016021"(integral component of membrane)|go:"GO:0031901"(early endosome membrane)|go:"GO:0031902"(late endosome membrane)|go:"GO:0042491"(inner ear auditory receptor cell differentiation)|go:"GO:0051289"(protein homotetramerization)|go:"GO:0060171"(stereocilium membrane)|go:"GO:0080025"(phosphatidylinositol-3,5-bisphosphate binding)|go:"GO:0097682"(intracellular phosphatidylinositol-3,5-bisphosphate-sensitive cation channel activity)|go:"GO:0098655"(cation transmembrane transport)|go:"GO:1905103"(integral component of lysosomal membrane)|interpro:IPR013122(Polycystin cation channel, PKD1/PKD2)|interpro:IPR039031|rcsb pdb:5W3S|go:"GO:0042802"(identical protein binding)|refseq:XP_002751067.1|refseq:XP_008999856.1	-	-	-	figure legend:Extended Data Fig 2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:7108(spofr-sf_9)|taxid:7108(Spodoptera frugiperda insect cells)	-	2020/10/16	2020/12/23	rogid:W2z/IDdxYUNs680IkN6C/LSl+0E9483	rogid:W2z/IDdxYUNs680IkN6C/LSl+0E9483	rigid:+h5DExFTxBMbTABvaGz7Up++b5o	false	mutation:52-52,58-58,62-62|binding-associated region:1-553	mutation:52-52,58-58,62-62|binding-associated region:1-553	4	0	psi-mi:"MI:2287"(identification by structure determination)	psi-mi:"MI:2287"(identification by structure determination)
uniprotkb:F6RG56	uniprotkb:F6RG56	intact:EBI-26372251|ensembl:ENSCJAP00000012762	intact:EBI-26372251|ensembl:ENSCJAP00000012762	psi-mi:mcln3_calja(display_long)|uniprotkb:MCOLN3(gene name)|psi-mi:MCOLN3(display_short)|uniprotkb:Transient receptor potential channel mucolipin 3(gene name synonym)	psi-mi:mcln3_calja(display_long)|uniprotkb:MCOLN3(gene name)|psi-mi:MCOLN3(display_short)|uniprotkb:Transient receptor potential channel mucolipin 3(gene name synonym)	psi-mi:"MI:0065"(isothermal titration calorimetry)	Hirschi et al. (2017)	pubmed:29019979|imex:IM-28635	taxid:9483(calja)|taxid:9483("Callithrix jacchus (White-tufted-ear marmoset)")	taxid:9483(calja)|taxid:9483("Callithrix jacchus (White-tufted-ear marmoset)")	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0465"(DIP)	intact:EBI-26568587|imex:IM-28635-15	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSCJAG00000006859(gene)|ensembl:ENSCJAT00000013447(transcript)|go:"GO:0000421"(autophagosome membrane)|go:"GO:0007626"(locomotory behavior)|go:"GO:0016021"(integral component of membrane)|go:"GO:0031901"(early endosome membrane)|go:"GO:0031902"(late endosome membrane)|go:"GO:0042491"(inner ear auditory receptor cell differentiation)|go:"GO:0051289"(protein homotetramerization)|go:"GO:0060171"(stereocilium membrane)|go:"GO:0080025"(phosphatidylinositol-3,5-bisphosphate binding)|go:"GO:0097682"(intracellular phosphatidylinositol-3,5-bisphosphate-sensitive cation channel activity)|go:"GO:0098655"(cation transmembrane transport)|go:"GO:1905103"(integral component of lysosomal membrane)|interpro:IPR013122(Polycystin cation channel, PKD1/PKD2)|interpro:IPR039031|rcsb pdb:5W3S|go:"GO:0042802"(identical protein binding)|refseq:XP_002751067.1|refseq:XP_008999856.1	ensembl:ENSCJAG00000006859(gene)|ensembl:ENSCJAT00000013447(transcript)|go:"GO:0000421"(autophagosome membrane)|go:"GO:0007626"(locomotory behavior)|go:"GO:0016021"(integral component of membrane)|go:"GO:0031901"(early endosome membrane)|go:"GO:0031902"(late endosome membrane)|go:"GO:0042491"(inner ear auditory receptor cell differentiation)|go:"GO:0051289"(protein homotetramerization)|go:"GO:0060171"(stereocilium membrane)|go:"GO:0080025"(phosphatidylinositol-3,5-bisphosphate binding)|go:"GO:0097682"(intracellular phosphatidylinositol-3,5-bisphosphate-sensitive cation channel activity)|go:"GO:0098655"(cation transmembrane transport)|go:"GO:1905103"(integral component of lysosomal membrane)|interpro:IPR013122(Polycystin cation channel, PKD1/PKD2)|interpro:IPR039031|rcsb pdb:5W3S|go:"GO:0042802"(identical protein binding)|refseq:XP_002751067.1|refseq:XP_008999856.1	-	-	-	figure legend:Extended Data Fig 2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:7108(spofr-sf_9)|taxid:7108(Spodoptera frugiperda insect cells)	-	2020/10/16	2020/12/23	rogid:W2z/IDdxYUNs680IkN6C/LSl+0E9483	rogid:W2z/IDdxYUNs680IkN6C/LSl+0E9483	rigid:+h5DExFTxBMbTABvaGz7Up++b5o	false	mutation:52-52|binding-associated region:1-553	mutation:52-52|binding-associated region:1-553	4	0	psi-mi:"MI:2287"(identification by structure determination)	psi-mi:"MI:2287"(identification by structure determination)
uniprotkb:F6RG56	uniprotkb:F6RG56	intact:EBI-26372251|ensembl:ENSCJAP00000012762	intact:EBI-26372251|ensembl:ENSCJAP00000012762	psi-mi:mcln3_calja(display_long)|uniprotkb:MCOLN3(gene name)|psi-mi:MCOLN3(display_short)|uniprotkb:Transient receptor potential channel mucolipin 3(gene name synonym)	psi-mi:mcln3_calja(display_long)|uniprotkb:MCOLN3(gene name)|psi-mi:MCOLN3(display_short)|uniprotkb:Transient receptor potential channel mucolipin 3(gene name synonym)	psi-mi:"MI:0065"(isothermal titration calorimetry)	Hirschi et al. (2017)	pubmed:29019979|imex:IM-28635	taxid:9483(calja)|taxid:9483("Callithrix jacchus (White-tufted-ear marmoset)")	taxid:9483(calja)|taxid:9483("Callithrix jacchus (White-tufted-ear marmoset)")	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0465"(DIP)	intact:EBI-26568597|imex:IM-28635-17	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSCJAG00000006859(gene)|ensembl:ENSCJAT00000013447(transcript)|go:"GO:0000421"(autophagosome membrane)|go:"GO:0007626"(locomotory behavior)|go:"GO:0016021"(integral component of membrane)|go:"GO:0031901"(early endosome membrane)|go:"GO:0031902"(late endosome membrane)|go:"GO:0042491"(inner ear auditory receptor cell differentiation)|go:"GO:0051289"(protein homotetramerization)|go:"GO:0060171"(stereocilium membrane)|go:"GO:0080025"(phosphatidylinositol-3,5-bisphosphate binding)|go:"GO:0097682"(intracellular phosphatidylinositol-3,5-bisphosphate-sensitive cation channel activity)|go:"GO:0098655"(cation transmembrane transport)|go:"GO:1905103"(integral component of lysosomal membrane)|interpro:IPR013122(Polycystin cation channel, PKD1/PKD2)|interpro:IPR039031|rcsb pdb:5W3S|go:"GO:0042802"(identical protein binding)|refseq:XP_002751067.1|refseq:XP_008999856.1	ensembl:ENSCJAG00000006859(gene)|ensembl:ENSCJAT00000013447(transcript)|go:"GO:0000421"(autophagosome membrane)|go:"GO:0007626"(locomotory behavior)|go:"GO:0016021"(integral component of membrane)|go:"GO:0031901"(early endosome membrane)|go:"GO:0031902"(late endosome membrane)|go:"GO:0042491"(inner ear auditory receptor cell differentiation)|go:"GO:0051289"(protein homotetramerization)|go:"GO:0060171"(stereocilium membrane)|go:"GO:0080025"(phosphatidylinositol-3,5-bisphosphate binding)|go:"GO:0097682"(intracellular phosphatidylinositol-3,5-bisphosphate-sensitive cation channel activity)|go:"GO:0098655"(cation transmembrane transport)|go:"GO:1905103"(integral component of lysosomal membrane)|interpro:IPR013122(Polycystin cation channel, PKD1/PKD2)|interpro:IPR039031|rcsb pdb:5W3S|go:"GO:0042802"(identical protein binding)|refseq:XP_002751067.1|refseq:XP_008999856.1	-	-	-	figure legend:Extended Data Fig 2|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:7108(spofr-sf_9)|taxid:7108(Spodoptera frugiperda insect cells)	-	2020/10/16	2020/12/23	rogid:W2z/IDdxYUNs680IkN6C/LSl+0E9483	rogid:W2z/IDdxYUNs680IkN6C/LSl+0E9483	rigid:+h5DExFTxBMbTABvaGz7Up++b5o	false	mutation:326-326|binding-associated region:1-553	mutation:326-326|binding-associated region:1-553	4	0	psi-mi:"MI:2287"(identification by structure determination)	psi-mi:"MI:2287"(identification by structure determination)