#ID(s) interactor A	ID(s) interactor B	Alt. ID(s) interactor A	Alt. ID(s) interactor B	Alias(es) interactor A	Alias(es) interactor B	Interaction detection method(s)	Publication 1st author(s)	Publication Identifier(s)	Taxid interactor A	Taxid interactor B	Interaction type(s)	Source database(s)	Interaction identifier(s)	Confidence value(s)	Expansion method(s)	Biological role(s) interactor A	Biological role(s) interactor B	Experimental role(s) interactor A	Experimental role(s) interactor B	Type(s) interactor A	Type(s) interactor B	Xref(s) interactor A	Xref(s) interactor B	Interaction Xref(s)	Annotation(s) interactor A	Annotation(s) interactor B	Interaction annotation(s)	Host organism(s)	Interaction parameter(s)	Creation date	Update date	Checksum(s) interactor A	Checksum(s) interactor B	Interaction Checksum(s)	Negative	Feature(s) interactor A	Feature(s) interactor B	Stoichiometry(s) interactor A	Stoichiometry(s) interactor B	Identification method participant A	Identification method participant B
uniprotkb:Q9NZQ7	uniprotkb:Q9NX76	intact:EBI-4314282|uniprotkb:B4DU27|uniprotkb:Q6WEX4|uniprotkb:B2RBA2|uniprotkb:Q66RK1|uniprotkb:Q9NUZ5|uniprotkb:Q14CJ2|uniprotkb:Q2V8D5|ensembl:ENSP00000370989	intact:EBI-1054315|uniprotkb:Q6IAC4|ensembl:ENSP00000205636	psi-mi:pd1l1_human(display_long)|uniprotkb:CD274(gene name)|psi-mi:CD274(display_short)|uniprotkb:B7H1(gene name synonym)|uniprotkb:PDCD1L1(gene name synonym)|uniprotkb:PDCD1LG1(gene name synonym)|uniprotkb:PDL1(gene name synonym)|uniprotkb:B7 homolog 1(gene name synonym)	psi-mi:cklf6_human(display_long)|uniprotkb:Chemokine-like factor superfamily member 6(gene name synonym)|uniprotkb:CMTM6(gene name)|psi-mi:CMTM6(display_short)|uniprotkb:CKLFSF6(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Burr et al. (2017)	pubmed:28813417|imex:IM-27858	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-25497531|imex:IM-27858-1	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_054862.1|refseq:NP_001254635.1|ensembl:ENSG00000120217(gene)|ensembl:ENST00000381577(transcript)|go:"GO:0002250"(adaptive immune response)|go:"GO:0002845"(positive regulation of tolerance induction to tumor cell)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0006955"(immune response)|go:"GO:0007165"(signal transduction)|go:"GO:0007166"(cell surface receptor signaling pathway)|go:"GO:0009897"(external side of plasma membrane)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0031295"(T cell costimulation)|go:"GO:0031901"(early endosome membrane)|go:"GO:0032689"(negative regulation of interferon-gamma production)|go:"GO:0032693"(negative regulation of interleukin-10 production)|go:"GO:0032733"(positive regulation of interleukin-10 production)|go:"GO:0034097"(response to cytokine)|go:"GO:0042102"(positive regulation of T cell proliferation)|go:"GO:0042130"(negative regulation of T cell proliferation)|go:"GO:0046007"(negative regulation of activated T cell proliferation)|go:"GO:0055038"(recycling endosome membrane)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071222"(cellular response to lipopolysaccharide)|go:"GO:1901998"(toxin transport)|go:"GO:1903556"(negative regulation of tumor necrosis factor superfamily cytokine production)|go:"GO:1905404"(positive regulation of activated CD8-positive, alpha-beta T cell apoptotic process)|go:"GO:2000562"(negative regulation of CD4-positive, alpha-beta T cell proliferation)|go:"GO:2001186"(negative regulation of CD8-positive, alpha-beta T cell activation)|interpro:IPR003599(Immunoglobulin subtype)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR013106(Immunoglobulin V-set)|interpro:IPR013162(CD80-like, immunoglobulin C2-set)|interpro:IPR013783(Immunoglobulin-like fold)|rcsb pdb:3BIK|rcsb pdb:3BIS|rcsb pdb:3FN3|rcsb pdb:3SBW|rcsb pdb:4Z18|rcsb pdb:4ZQK|rcsb pdb:5C3T|rcsb pdb:5GGT|rcsb pdb:5GRJ|rcsb pdb:5IUS|rcsb pdb:5J89|rcsb pdb:5J8O|rcsb pdb:5JDR|rcsb pdb:5JDS|rcsb pdb:5N2D|rcsb pdb:5N2F|rcsb pdb:5NIU|rcsb pdb:5O45|rcsb pdb:5O4Y|rcsb pdb:5X8L|rcsb pdb:5X8M|rcsb pdb:5XJ4|rcsb pdb:5XXY|rcsb pdb:6L8R|rcsb pdb:6NM7|rcsb pdb:6NM8|rcsb pdb:6NNV|rcsb pdb:6NOJ|rcsb pdb:6NOS|rcsb pdb:6NP9|rcsb pdb:6PV9|rcsb pdb:6R3K|rcsb pdb:6RPG|rcsb pdb:6VQN|rcsb pdb:6YCR|rcsb pdb:7BEA|rcsb pdb:7C88|reactome:R-HSA-389948|interpro:IPR036179|dip:DIP-29731N	refseq:NP_060271.1|ensembl:ENSG00000091317(gene)|ensembl:ENST00000205636(transcript)|go:"GO:0005886"(plasma membrane)|go:"GO:0015031"(protein transport)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0031647"(regulation of protein stability)|go:"GO:0031901"(early endosome membrane)|go:"GO:0032456"(endocytic recycling)|go:"GO:0035577"(azurophil granule membrane)|go:"GO:0035579"(specific granule membrane)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0055038"(recycling endosome membrane)|interpro:IPR008253(Marvel)|reactome:R-HSA-6798695	-	-	-	figure legend:2a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-mda_mb_231)|taxid:9606(Homo sapiens Caucasian breast adenocarcinoma)	-	2020/04/01	2020/04/01	rogid:xgS8qLw0RrD1mMV3JswLYfX8NBQ9606	rogid:OrVBhhmdJZSWGfyJc/eYUYNtdYE9606	rigid:b99ilUflmon539j6LK7WReyslzo	false	-	-	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:Q9NZQ7	uniprotkb:Q9NX76	intact:EBI-4314282|uniprotkb:B4DU27|uniprotkb:Q6WEX4|uniprotkb:B2RBA2|uniprotkb:Q66RK1|uniprotkb:Q9NUZ5|uniprotkb:Q14CJ2|uniprotkb:Q2V8D5|ensembl:ENSP00000370989	intact:EBI-1054315|uniprotkb:Q6IAC4|ensembl:ENSP00000205636	psi-mi:pd1l1_human(display_long)|uniprotkb:CD274(gene name)|psi-mi:CD274(display_short)|uniprotkb:B7H1(gene name synonym)|uniprotkb:PDCD1L1(gene name synonym)|uniprotkb:PDCD1LG1(gene name synonym)|uniprotkb:PDL1(gene name synonym)|uniprotkb:B7 homolog 1(gene name synonym)	psi-mi:cklf6_human(display_long)|uniprotkb:Chemokine-like factor superfamily member 6(gene name synonym)|uniprotkb:CMTM6(gene name)|psi-mi:CMTM6(display_short)|uniprotkb:CKLFSF6(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Burr et al. (2017)	pubmed:28813417|imex:IM-27858	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-25497538|imex:IM-27858-3	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_054862.1|refseq:NP_001254635.1|ensembl:ENSG00000120217(gene)|ensembl:ENST00000381577(transcript)|go:"GO:0002250"(adaptive immune response)|go:"GO:0002845"(positive regulation of tolerance induction to tumor cell)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0006955"(immune response)|go:"GO:0007165"(signal transduction)|go:"GO:0007166"(cell surface receptor signaling pathway)|go:"GO:0009897"(external side of plasma membrane)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0031295"(T cell costimulation)|go:"GO:0031901"(early endosome membrane)|go:"GO:0032689"(negative regulation of interferon-gamma production)|go:"GO:0032693"(negative regulation of interleukin-10 production)|go:"GO:0032733"(positive regulation of interleukin-10 production)|go:"GO:0034097"(response to cytokine)|go:"GO:0042102"(positive regulation of T cell proliferation)|go:"GO:0042130"(negative regulation of T cell proliferation)|go:"GO:0046007"(negative regulation of activated T cell proliferation)|go:"GO:0055038"(recycling endosome membrane)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071222"(cellular response to lipopolysaccharide)|go:"GO:1901998"(toxin transport)|go:"GO:1903556"(negative regulation of tumor necrosis factor superfamily cytokine production)|go:"GO:1905404"(positive regulation of activated CD8-positive, alpha-beta T cell apoptotic process)|go:"GO:2000562"(negative regulation of CD4-positive, alpha-beta T cell proliferation)|go:"GO:2001186"(negative regulation of CD8-positive, alpha-beta T cell activation)|interpro:IPR003599(Immunoglobulin subtype)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR013106(Immunoglobulin V-set)|interpro:IPR013162(CD80-like, immunoglobulin C2-set)|interpro:IPR013783(Immunoglobulin-like fold)|rcsb pdb:3BIK|rcsb pdb:3BIS|rcsb pdb:3FN3|rcsb pdb:3SBW|rcsb pdb:4Z18|rcsb pdb:4ZQK|rcsb pdb:5C3T|rcsb pdb:5GGT|rcsb pdb:5GRJ|rcsb pdb:5IUS|rcsb pdb:5J89|rcsb pdb:5J8O|rcsb pdb:5JDR|rcsb pdb:5JDS|rcsb pdb:5N2D|rcsb pdb:5N2F|rcsb pdb:5NIU|rcsb pdb:5O45|rcsb pdb:5O4Y|rcsb pdb:5X8L|rcsb pdb:5X8M|rcsb pdb:5XJ4|rcsb pdb:5XXY|rcsb pdb:6L8R|rcsb pdb:6NM7|rcsb pdb:6NM8|rcsb pdb:6NNV|rcsb pdb:6NOJ|rcsb pdb:6NOS|rcsb pdb:6NP9|rcsb pdb:6PV9|rcsb pdb:6R3K|rcsb pdb:6RPG|rcsb pdb:6VQN|rcsb pdb:6YCR|rcsb pdb:7BEA|rcsb pdb:7C88|reactome:R-HSA-389948|interpro:IPR036179|dip:DIP-29731N	refseq:NP_060271.1|ensembl:ENSG00000091317(gene)|ensembl:ENST00000205636(transcript)|go:"GO:0005886"(plasma membrane)|go:"GO:0015031"(protein transport)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0031647"(regulation of protein stability)|go:"GO:0031901"(early endosome membrane)|go:"GO:0032456"(endocytic recycling)|go:"GO:0035577"(azurophil granule membrane)|go:"GO:0035579"(specific granule membrane)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0055038"(recycling endosome membrane)|interpro:IPR008253(Marvel)|reactome:R-HSA-6798695	-	-	-	figure legend:2a,b|antagonist:TX-100 detergent treatment|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-mda_mb_231)|taxid:9606(Homo sapiens Caucasian breast adenocarcinoma)	-	2020/04/01	2020/04/01	rogid:xgS8qLw0RrD1mMV3JswLYfX8NBQ9606	rogid:OrVBhhmdJZSWGfyJc/eYUYNtdYE9606	rigid:b99ilUflmon539j6LK7WReyslzo	false	-	-	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:Q9NZQ7	uniprotkb:Q9NX76	intact:EBI-4314282|uniprotkb:B4DU27|uniprotkb:Q6WEX4|uniprotkb:B2RBA2|uniprotkb:Q66RK1|uniprotkb:Q9NUZ5|uniprotkb:Q14CJ2|uniprotkb:Q2V8D5|ensembl:ENSP00000370989	intact:EBI-1054315|uniprotkb:Q6IAC4|ensembl:ENSP00000205636	psi-mi:pd1l1_human(display_long)|uniprotkb:CD274(gene name)|psi-mi:CD274(display_short)|uniprotkb:B7H1(gene name synonym)|uniprotkb:PDCD1L1(gene name synonym)|uniprotkb:PDCD1LG1(gene name synonym)|uniprotkb:PDL1(gene name synonym)|uniprotkb:B7 homolog 1(gene name synonym)	psi-mi:cklf6_human(display_long)|uniprotkb:Chemokine-like factor superfamily member 6(gene name synonym)|uniprotkb:CMTM6(gene name)|psi-mi:CMTM6(display_short)|uniprotkb:CKLFSF6(gene name synonym)	psi-mi:"MI:0663"(confocal microscopy)	Burr et al. (2017)	pubmed:28813417|imex:IM-27858	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0403"(colocalization)	psi-mi:"MI:0469"(IntAct)	intact:EBI-25497553|imex:IM-27858-5	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_054862.1|refseq:NP_001254635.1|ensembl:ENSG00000120217(gene)|ensembl:ENST00000381577(transcript)|go:"GO:0002250"(adaptive immune response)|go:"GO:0002845"(positive regulation of tolerance induction to tumor cell)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0006955"(immune response)|go:"GO:0007165"(signal transduction)|go:"GO:0007166"(cell surface receptor signaling pathway)|go:"GO:0009897"(external side of plasma membrane)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0031295"(T cell costimulation)|go:"GO:0031901"(early endosome membrane)|go:"GO:0032689"(negative regulation of interferon-gamma production)|go:"GO:0032693"(negative regulation of interleukin-10 production)|go:"GO:0032733"(positive regulation of interleukin-10 production)|go:"GO:0034097"(response to cytokine)|go:"GO:0042102"(positive regulation of T cell proliferation)|go:"GO:0042130"(negative regulation of T cell proliferation)|go:"GO:0046007"(negative regulation of activated T cell proliferation)|go:"GO:0055038"(recycling endosome membrane)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071222"(cellular response to lipopolysaccharide)|go:"GO:1901998"(toxin transport)|go:"GO:1903556"(negative regulation of tumor necrosis factor superfamily cytokine production)|go:"GO:1905404"(positive regulation of activated CD8-positive, alpha-beta T cell apoptotic process)|go:"GO:2000562"(negative regulation of CD4-positive, alpha-beta T cell proliferation)|go:"GO:2001186"(negative regulation of CD8-positive, alpha-beta T cell activation)|interpro:IPR003599(Immunoglobulin subtype)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR013106(Immunoglobulin V-set)|interpro:IPR013162(CD80-like, immunoglobulin C2-set)|interpro:IPR013783(Immunoglobulin-like fold)|rcsb pdb:3BIK|rcsb pdb:3BIS|rcsb pdb:3FN3|rcsb pdb:3SBW|rcsb pdb:4Z18|rcsb pdb:4ZQK|rcsb pdb:5C3T|rcsb pdb:5GGT|rcsb pdb:5GRJ|rcsb pdb:5IUS|rcsb pdb:5J89|rcsb pdb:5J8O|rcsb pdb:5JDR|rcsb pdb:5JDS|rcsb pdb:5N2D|rcsb pdb:5N2F|rcsb pdb:5NIU|rcsb pdb:5O45|rcsb pdb:5O4Y|rcsb pdb:5X8L|rcsb pdb:5X8M|rcsb pdb:5XJ4|rcsb pdb:5XXY|rcsb pdb:6L8R|rcsb pdb:6NM7|rcsb pdb:6NM8|rcsb pdb:6NNV|rcsb pdb:6NOJ|rcsb pdb:6NOS|rcsb pdb:6NP9|rcsb pdb:6PV9|rcsb pdb:6R3K|rcsb pdb:6RPG|rcsb pdb:6VQN|rcsb pdb:6YCR|rcsb pdb:7BEA|rcsb pdb:7C88|reactome:R-HSA-389948|interpro:IPR036179|dip:DIP-29731N	refseq:NP_060271.1|ensembl:ENSG00000091317(gene)|ensembl:ENST00000205636(transcript)|go:"GO:0005886"(plasma membrane)|go:"GO:0015031"(protein transport)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0031647"(regulation of protein stability)|go:"GO:0031901"(early endosome membrane)|go:"GO:0032456"(endocytic recycling)|go:"GO:0035577"(azurophil granule membrane)|go:"GO:0035579"(specific granule membrane)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0055038"(recycling endosome membrane)|interpro:IPR008253(Marvel)|reactome:R-HSA-6798695	go:"GO:0005886"(plasma membrane)	-	-	figure legend:2c|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-mda_mb_231)|taxid:9606(Homo sapiens Caucasian breast adenocarcinoma)	-	2020/04/01	2020/04/01	rogid:xgS8qLw0RrD1mMV3JswLYfX8NBQ9606	rogid:OrVBhhmdJZSWGfyJc/eYUYNtdYE9606	rigid:b99ilUflmon539j6LK7WReyslzo	false	-	-	-	-	psi-mi:"MI:0422"(immunostaining)	psi-mi:"MI:0422"(immunostaining)