#ID(s) interactor A ID(s) interactor B Alt. ID(s) interactor A Alt. ID(s) interactor B Alias(es) interactor A Alias(es) interactor B Interaction detection method(s) Publication 1st author(s) Publication Identifier(s) Taxid interactor A Taxid interactor B Interaction type(s) Source database(s) Interaction identifier(s) Confidence value(s) Expansion method(s) Biological role(s) interactor A Biological role(s) interactor B Experimental role(s) interactor A Experimental role(s) interactor B Type(s) interactor A Type(s) interactor B Xref(s) interactor A Xref(s) interactor B Interaction Xref(s) Annotation(s) interactor A Annotation(s) interactor B Interaction annotation(s) Host organism(s) Interaction parameter(s) Creation date Update date Checksum(s) interactor A Checksum(s) interactor B Interaction Checksum(s) Negative Feature(s) interactor A Feature(s) interactor B Stoichiometry(s) interactor A Stoichiometry(s) interactor B Identification method participant A Identification method participant B intact:EBI-25682775 intact:EBI-25772477 ensembl:ENST00000337514 rnacentral:URS000024A59E_9606 psi-mi:mrna_igf1(display_short)|psi-mi:EBI-25682775(display_long) psi-mi:hsa-mir-128-3p(display_short)|psi-mi:EBI-25772477(display_long) psi-mi:"MI:2285"(miRNA interference luciferase reporter assay) Chen et al. (2015) imex:IM-28322|pubmed:27893811 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-25772487|imex:IM-28322-1 - - psi-mi:"MI:2275"(regulator target) psi-mi:"MI:2274"(regulator) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0324"(messenger rna) psi-mi:"MI:2204"(micro rna) refseq:NM_000618.5(see-also)|ensembl:ENSG00000017427(see-also) - go:"GO:1903231"(mRNA binding involved in posttranscriptional gene silencing) - - figure legend:Fig 6 A, B|causality statement:down-regulates quantity by destabilization|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-u87)|taxid:9606(Human U-87 MG glioblastoma cell line) - 2020/08/06 2020/08/07 - - - false luciferase tag:0-0|mutation decreasing interaction:1874-1878 - - - psi-mi:"MI:1220"(tag visualisation by luciferase assay) psi-mi:"MI:1220"(tag visualisation by luciferase assay) intact:EBI-25773021 intact:EBI-25772477 ensembl:ENST00000521381 rnacentral:URS000024A59E_9606 psi-mi:mrna_pik3r1(display_short)|psi-mi:EBI-25773021(display_long) psi-mi:hsa-mir-128-3p(display_short)|psi-mi:EBI-25772477(display_long) psi-mi:"MI:2285"(miRNA interference luciferase reporter assay) Chen et al. (2015) imex:IM-28322|pubmed:27893811 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-25773001|imex:IM-28322-3 - - psi-mi:"MI:2275"(regulator target) psi-mi:"MI:2274"(regulator) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0324"(messenger rna) psi-mi:"MI:2204"(micro rna) ensembl:ENSG00000145675(see-also)|refseq:NM_181523.3(see-also) - go:"GO:1903231"(mRNA binding involved in posttranscriptional gene silencing) - - figure legend:Fig 6 A, B|causality statement:down-regulates quantity by destabilization|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-u87)|taxid:9606(Human U-87 MG glioblastoma cell line) - 2020/08/06 2020/08/07 - - - false mutation decreasing interaction:3242-3246|luciferase tag:0-0 - - - psi-mi:"MI:1220"(tag visualisation by luciferase assay) psi-mi:"MI:1220"(tag visualisation by luciferase assay) intact:EBI-25773402 intact:EBI-25772477 ensembl:ENST00000361445 rnacentral:URS000024A59E_9606 psi-mi:mrna_mtor(display_short)|psi-mi:EBI-25773402(display_long) psi-mi:hsa-mir-128-3p(display_short)|psi-mi:EBI-25772477(display_long) psi-mi:"MI:2285"(miRNA interference luciferase reporter assay) Chen et al. (2015) imex:IM-28322|pubmed:27893811 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-25773011|imex:IM-28322-5 - - psi-mi:"MI:2275"(regulator target) psi-mi:"MI:2274"(regulator) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0324"(messenger rna) psi-mi:"MI:2204"(micro rna) ensembl:ENSG00000198793(see-also)|refseq:NM_004958(see-also) - go:"GO:1903231"(mRNA binding involved in posttranscriptional gene silencing) - - figure legend:Fig 6 A, B|causality statement:down-regulates quantity by destabilization|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-u87)|taxid:9606(Human U-87 MG glioblastoma cell line) - 2020/08/06 2020/08/08 - - - false luciferase tag:0-0|mutation decreasing interaction:8451-8455 - - - psi-mi:"MI:1220"(tag visualisation by luciferase assay) psi-mi:"MI:1220"(tag visualisation by luciferase assay) intact:EBI-25773037 intact:EBI-25772477 ensembl:ENST00000357387 rnacentral:URS000024A59E_9606 psi-mi:mrna_rictor(display_short)|psi-mi:EBI-25773037(display_long) psi-mi:hsa-mir-128-3p(display_short)|psi-mi:EBI-25772477(display_long) psi-mi:"MI:2285"(miRNA interference luciferase reporter assay) Chen et al. (2015) imex:IM-28322|pubmed:27893811 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-25773016|imex:IM-28322-7 - - psi-mi:"MI:2275"(regulator target) psi-mi:"MI:2274"(regulator) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0324"(messenger rna) psi-mi:"MI:2204"(micro rna) ensembl:ENSG00000164327(see-also)|refseq:NM_152756.5(see-also) - go:"GO:1903231"(mRNA binding involved in posttranscriptional gene silencing) - - figure legend:Fig 6 A, B|causality statement:down-regulates quantity by destabilization|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-u87)|taxid:9606(Human U-87 MG glioblastoma cell line) - 2020/08/06 2020/08/08 - - - false luciferase tag:0-0|mutation decreasing interaction:6784-6788 - - - psi-mi:"MI:1220"(tag visualisation by luciferase assay) psi-mi:"MI:1220"(tag visualisation by luciferase assay) uniprotkb:P05412 ensembl:ENSG00000207654 intact:EBI-852823|uniprotkb:Q96G93|uniprotkb:Q6FHM7|ensembl:ENSP00000360266|ensembl:ENSP00000503132 intact:EBI-25773433 psi-mi:jun_human(display_long)|uniprotkb:JUN(gene name)|psi-mi:JUN(display_short)|uniprotkb:Activator protein 1(gene name synonym)|uniprotkb:Proto-oncogene c-Jun(gene name synonym)|uniprotkb:V-jun avian sarcoma virus 17 oncogene homolog(gene name synonym)|uniprotkb:p39(gene name synonym) psi-mi:mir128-1 gene(display_short)|psi-mi:ENSG00000207654(display_long) psi-mi:"MI:0402"(chromatin immunoprecipitation assay) Chen et al. (2015) imex:IM-28322|pubmed:27893811 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-25773435|imex:IM-28322-9 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0250"(gene) refseq:NP_002219.1|ensembl:ENSP00000360266|ensembl:ENSP00000503132|dip:DIP-5961N|ensembl:ENSG00000177606(gene)|ensembl:ENST00000371222(transcript)|ensembl:ENST00000678696(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000228"(nuclear chromosome)|go:"GO:0000785"(chromatin)|go:"GO:0000791"(euchromatin)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001525"(angiogenesis)|go:"GO:0001836"(release of cytochrome c from mitochondria)|go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0003723"(RNA binding)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0007179"(transforming growth factor beta receptor signaling pathway)|go:"GO:0007265"(Ras protein signal transduction)|go:"GO:0007568"(aging)|go:"GO:0007612"(learning)|go:"GO:0007623"(circadian rhythm)|go:"GO:0008134"(transcription factor binding)|go:"GO:0009314"(response to radiation)|go:"GO:0009612"(response to mechanical stimulus)|go:"GO:0019899"(enzyme binding)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032496"(response to lipopolysaccharide)|go:"GO:0034097"(response to cytokine)|go:"GO:0034614"(cellular response to reactive oxygen species)|go:"GO:0035497"(cAMP response element binding)|go:"GO:0035976"(transcription factor AP-1 complex)|go:"GO:0042127"(regulation of cell population proliferation)|go:"GO:0042493"|go:"GO:0042542"(response to hydrogen peroxide)|go:"GO:0042802"(identical protein binding)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043392"(negative regulation of DNA binding)|go:"GO:0043525"(positive regulation of neuron apoptotic process)|go:"GO:0043922"(negative regulation by host of viral transcription)|go:"GO:0043923"(positive regulation by host of viral transcription)|go:"GO:0044389"(ubiquitin-like protein ligase binding)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045657"(positive regulation of monocyte differentiation)|go:"GO:0045740"(positive regulation of DNA replication)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0051365"(cellular response to potassium ion starvation)|go:"GO:0051591"(response to cAMP)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0051899"(membrane depolarization)|go:"GO:0060395"(SMAD protein signal transduction)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:0070412"(R-SMAD binding)|go:"GO:0071276"(cellular response to cadmium ion)|go:"GO:0071837"(HMG box domain binding)|go:"GO:1902895"(positive regulation of miRNA transcription)|go:"GO:1904707"(positive regulation of vascular associated smooth muscle cell proliferation)|go:"GO:1990441"(negative regulation of transcription from RNA polymerase II promoter in response to endoplasmic reticulum stress)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|go:"GO:2000144"(positive regulation of DNA-templated transcription, initiation)|interpro:IPR002112(Transcription factor Jun)|interpro:IPR004827("Basic-leucine zipper (bZIP) transcription factor")|interpro:IPR005643(Jun-like transcription factor)|interpro:IPR008917(Eukaryotic transcription factor, Skn-1-like, DNA-binding)|interpro:IPR015558(c-Jun Transcription Factor)|mint:P05412|rcsb pdb:1A02|rcsb pdb:1FOS|rcsb pdb:1JNM|rcsb pdb:1JUN|rcsb pdb:1S9K|rcsb pdb:1T2K|rcsb pdb:5FV8|rcsb pdb:5T01|rcsb pdb:6Y3V|reactome:R-HSA-1912408|reactome:R-HSA-2559580|reactome:R-HSA-2559582|reactome:R-HSA-2871796|reactome:R-HSA-450341|reactome:R-HSA-5617472|reactome:R-HSA-5687128|reactome:R-HSA-6796648|reactome:R-HSA-8862803|reactome:R-HSA-8943724|reactome:R-HSA-9018519|reactome:R-HSA-9673324 - - - - figure legend:Fig 4 E|caution:Not possible to univocally identify the Immunoprecipitated region of miRNA 128 promoter|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-u87)|taxid:9606(Human U-87 MG glioblastoma cell line) - 2020/08/06 2020/08/08 rogid:zAVYwedHKKdvPPGttBP4XZkbCXA9606 - - false - - - - psi-mi:"MI:0421"(identification by antibody) psi-mi:"MI:0088"(primer specific pcr)