#ID(s) interactor A ID(s) interactor B Alt. ID(s) interactor A Alt. ID(s) interactor B Alias(es) interactor A Alias(es) interactor B Interaction detection method(s) Publication 1st author(s) Publication Identifier(s) Taxid interactor A Taxid interactor B Interaction type(s) Source database(s) Interaction identifier(s) Confidence value(s) Expansion method(s) Biological role(s) interactor A Biological role(s) interactor B Experimental role(s) interactor A Experimental role(s) interactor B Type(s) interactor A Type(s) interactor B Xref(s) interactor A Xref(s) interactor B Interaction Xref(s) Annotation(s) interactor A Annotation(s) interactor B Interaction annotation(s) Host organism(s) Interaction parameter(s) Creation date Update date Checksum(s) interactor A Checksum(s) interactor B Interaction Checksum(s) Negative Feature(s) interactor A Feature(s) interactor B Stoichiometry(s) interactor A Stoichiometry(s) interactor B Identification method participant A Identification method participant B uniprotkb:P03452 uniprotkb:O76036 intact:EBI-2548105|uniprotkb:A4GXH4|uniprotkb:Q20N38|uniprotkb:Q83964|uniprotkb:Q8JUU5 intact:EBI-13915737|uniprotkb:B0V3L2|uniprotkb:B0V3L3|uniprotkb:B0V3L4|uniprotkb:B0V3L5|uniprotkb:B8JL03|uniprotkb:O76016|uniprotkb:O76017|uniprotkb:O76018|ensembl:ENSP00000478507|ensembl:ENSP00000481971|ensembl:ENSP00000482423|ensembl:ENSP00000483452|ensembl:ENSP00000484221|ensembl:ENSP00000484520 psi-mi:hema_i34a1(display_long)|uniprotkb:HA(gene name)|psi-mi:HA(display_short) psi-mi:nctr1_human(display_long)|uniprotkb:NCR1(gene name)|psi-mi:NCR1(display_short)|uniprotkb:LY94(gene name synonym)|uniprotkb:Lymphocyte antigen 94 homolog(gene name synonym)|uniprotkb:NK cell-activating receptor(gene name synonym)|uniprotkb:Natural killer cell p46-related protein(gene name synonym) psi-mi:"MI:0892"(solid phase assay) Duev-Cohen et al. (2016) pubmed:26919106|imex:IM-28404 taxid:211044(i34a1)|taxid:211044("Influenza A virus (strain A/Puerto Rico/8/1934 H1N1)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0469"(IntAct) intact:EBI-26364975|imex:IM-28404-1 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0000139"(Golgi membrane)|go:"GO:0005576"(extracellular region)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005886"(plasma membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0019031"(viral envelope)|go:"GO:0019062"(virion attachment to host cell)|go:"GO:0019064"(fusion of virus membrane with host plasma membrane)|go:"GO:0020002"(host cell plasma membrane)|go:"GO:0030666"(endocytic vesicle membrane)|go:"GO:0031904"(endosome lumen)|go:"GO:0039654"(fusion of virus membrane with host endosome membrane)|go:"GO:0046789"(host cell surface receptor binding)|go:"GO:0055036"(virion membrane)|go:"GO:0075512"(clathrin-dependent endocytosis of virus by host cell)|rcsb pdb:1RU7|rcsb pdb:1RVX|rcsb pdb:1RVZ|reactome:R-HSA-168255|reactome:R-HSA-168275|reactome:R-HSA-168288|reactome:R-HSA-168298|reactome:R-HSA-168302|reactome:R-HSA-168303|reactome:R-HSA-168316|reactome:R-HSA-168336|reactome:R-HSA-168874|reactome:R-HSA-192823|reactome:R-HSA-198933|go:"GO:0046761"(viral budding from plasma membrane)|refseq:NP_040980.1|interpro:IPR008980(Viral capsid/haemagglutinin protein)|interpro:IPR013828(Haemagglutinin, HA1 chain, alpha/beta region)|interpro:IPR000149(Haemagglutinin, influenza A/B virus type, HA1 chain)|interpro:IPR001364(Haemagglutinin, influenza A/B virus type, HA1/HA2 chain)|mint:P03452 refseq:NP_001138929.2|refseq:NP_001138930.2|refseq:NP_001229285.1|refseq:NP_001229286.1|refseq:NP_004820.2|ensembl:ENSG00000273535(gene)|ensembl:ENSG00000275156(gene)|ensembl:ENSG00000278362(gene)|ensembl:ENST00000610621(transcript)|ensembl:ENST00000612896(transcript)|ensembl:ENST00000615622(transcript)|ensembl:ENST00000617154(transcript)|ensembl:ENST00000617784(transcript)|ensembl:ENST00000619077(transcript)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006968"(cellular defense response)|go:"GO:0007165"(signal transduction)|go:"GO:0016514"(SWI/SNF complex)|go:"GO:0030101"(natural killer cell activation)|go:"GO:0042269"(regulation of natural killer cell mediated cytotoxicity)|interpro:IPR003599(Immunoglobulin subtype)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR036179|rcsb pdb:1OLL|rcsb pdb:1P6F|rcsb pdb:6IAP|reactome:R-HSA-198933 - - - figure legend:3C|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2020/09/30 2020/10/06 rogid:gouXSFq22QLERoidFm6ju2SwoIE211044 rogid:FzfU+jTvlPUvjgqpbZjkL7NYZt09606 rigid:cK3SedOUTAkKVy9ENi8OJOZu8As false fc-igg tag:?-?|biotin tag:?-? fc-igg tag:?-? - - psi-mi:"MI:0866"(tag visualisation) psi-mi:"MI:0866"(tag visualisation) uniprotkb:P03452 uniprotkb:Q96DU3 intact:EBI-2548105|uniprotkb:A4GXH4|uniprotkb:Q20N38|uniprotkb:Q83964|uniprotkb:Q8JUU5 intact:EBI-14058448|uniprotkb:A6NMW2|uniprotkb:B2R8X8|uniprotkb:Q14CF0|uniprotkb:Q5TAS4|uniprotkb:Q5TAS6|uniprotkb:Q5TAT3|uniprotkb:Q96DV0|ensembl:ENSP00000357036 psi-mi:hema_i34a1(display_long)|uniprotkb:HA(gene name)|psi-mi:HA(display_short) psi-mi:slaf6_human(display_long)|uniprotkb:KALI(gene name synonym)|uniprotkb:SLAMF6(gene name)|psi-mi:SLAMF6(display_short)|uniprotkb:Activating NK receptor(gene name synonym)|uniprotkb:NK-T-B-antigen(gene name synonym)|uniprotkb:UNQ6123/PRO20080(orf name) psi-mi:"MI:0892"(solid phase assay) Duev-Cohen et al. (2016) pubmed:26919106|imex:IM-28404 taxid:211044(i34a1)|taxid:211044("Influenza A virus (strain A/Puerto Rico/8/1934 H1N1)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0469"(IntAct) intact:EBI-26364996|imex:IM-28404-3 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0000139"(Golgi membrane)|go:"GO:0005576"(extracellular region)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005886"(plasma membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0019031"(viral envelope)|go:"GO:0019062"(virion attachment to host cell)|go:"GO:0019064"(fusion of virus membrane with host plasma membrane)|go:"GO:0020002"(host cell plasma membrane)|go:"GO:0030666"(endocytic vesicle membrane)|go:"GO:0031904"(endosome lumen)|go:"GO:0039654"(fusion of virus membrane with host endosome membrane)|go:"GO:0046789"(host cell surface receptor binding)|go:"GO:0055036"(virion membrane)|go:"GO:0075512"(clathrin-dependent endocytosis of virus by host cell)|rcsb pdb:1RU7|rcsb pdb:1RVX|rcsb pdb:1RVZ|reactome:R-HSA-168255|reactome:R-HSA-168275|reactome:R-HSA-168288|reactome:R-HSA-168298|reactome:R-HSA-168302|reactome:R-HSA-168303|reactome:R-HSA-168316|reactome:R-HSA-168336|reactome:R-HSA-168874|reactome:R-HSA-192823|reactome:R-HSA-198933|go:"GO:0046761"(viral budding from plasma membrane)|refseq:NP_040980.1|interpro:IPR008980(Viral capsid/haemagglutinin protein)|interpro:IPR013828(Haemagglutinin, HA1 chain, alpha/beta region)|interpro:IPR000149(Haemagglutinin, influenza A/B virus type, HA1 chain)|interpro:IPR001364(Haemagglutinin, influenza A/B virus type, HA1/HA2 chain)|mint:P03452 refseq:NP_001171643.1|refseq:NP_001171644.1|refseq:NP_001171645.1|refseq:NP_443163.1|ensembl:ENSG00000162739(gene)|ensembl:ENST00000368057(transcript)|go:"GO:0005886"(plasma membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0032729"(positive regulation of interferon-gamma production)|go:"GO:0032740"(positive regulation of interleukin-17 production)|go:"GO:0045087"(innate immune response)|go:"GO:0045954"(positive regulation of natural killer cell mediated cytotoxicity)|go:"GO:0070062"(extracellular exosome)|go:"GO:0072540"(T-helper 17 cell lineage commitment)|interpro:IPR003599(Immunoglobulin subtype)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR013106(Immunoglobulin V-set)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR036179|rcsb pdb:2IF7|reactome:R-HSA-198933 - - - figure legend:3C|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2020/09/30 2020/10/06 rogid:gouXSFq22QLERoidFm6ju2SwoIE211044 rogid:rUujUH968ooEkRgUiIeCBZbsjCs9606 rigid:XpsE8n18JPMxWxKq8la1of/rDFg false fc-igg tag:?-?|biotin tag:?-? fc-igg tag:?-?|sufficient binding region:1-226 - - psi-mi:"MI:0866"(tag visualisation) psi-mi:"MI:0866"(tag visualisation) uniprotkb:P03452 uniprotkb:Q9BZW8 intact:EBI-2548105|uniprotkb:A4GXH4|uniprotkb:Q20N38|uniprotkb:Q83964|uniprotkb:Q8JUU5 intact:EBI-1580565|uniprotkb:Q96T47|uniprotkb:Q9NQD2|uniprotkb:Q9NQD3|uniprotkb:Q9Y288|uniprotkb:Q5VYI2|uniprotkb:Q5VYI6|uniprotkb:Q5VYI7|ensembl:ENSP00000357012 psi-mi:hema_i34a1(display_long)|uniprotkb:HA(gene name)|psi-mi:HA(display_short) psi-mi:cd244_human(display_long)|uniprotkb:NK cell type I receptor protein 2B4(gene name synonym)|uniprotkb:NK cell activation-inducing ligand(gene name synonym)|uniprotkb:CD244(gene name)|psi-mi:CD244(display_short)|uniprotkb:2B4(gene name synonym)|uniprotkb:SLAM family member 4(gene name synonym)|uniprotkb:Signaling lymphocytic activation molecule 4(gene name synonym) psi-mi:"MI:0892"(solid phase assay) Duev-Cohen et al. (2016) pubmed:26919106|imex:IM-28404 taxid:211044(i34a1)|taxid:211044("Influenza A virus (strain A/Puerto Rico/8/1934 H1N1)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0469"(IntAct) intact:EBI-26365016|imex:IM-28404-5 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0000139"(Golgi membrane)|go:"GO:0005576"(extracellular region)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005886"(plasma membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0019031"(viral envelope)|go:"GO:0019062"(virion attachment to host cell)|go:"GO:0019064"(fusion of virus membrane with host plasma membrane)|go:"GO:0020002"(host cell plasma membrane)|go:"GO:0030666"(endocytic vesicle membrane)|go:"GO:0031904"(endosome lumen)|go:"GO:0039654"(fusion of virus membrane with host endosome membrane)|go:"GO:0046789"(host cell surface receptor binding)|go:"GO:0055036"(virion membrane)|go:"GO:0075512"(clathrin-dependent endocytosis of virus by host cell)|rcsb pdb:1RU7|rcsb pdb:1RVX|rcsb pdb:1RVZ|reactome:R-HSA-168255|reactome:R-HSA-168275|reactome:R-HSA-168288|reactome:R-HSA-168298|reactome:R-HSA-168302|reactome:R-HSA-168303|reactome:R-HSA-168316|reactome:R-HSA-168336|reactome:R-HSA-168874|reactome:R-HSA-192823|reactome:R-HSA-198933|go:"GO:0046761"(viral budding from plasma membrane)|refseq:NP_040980.1|interpro:IPR008980(Viral capsid/haemagglutinin protein)|interpro:IPR013828(Haemagglutinin, HA1 chain, alpha/beta region)|interpro:IPR000149(Haemagglutinin, influenza A/B virus type, HA1 chain)|interpro:IPR001364(Haemagglutinin, influenza A/B virus type, HA1/HA2 chain)|mint:P03452 refseq:XP_011507924.1|refseq:NP_001160135.1|refseq:NP_001160136.1|refseq:NP_057466.1|dip:DIP-40331N|ensembl:ENSG00000122223(gene)|ensembl:ENST00000368033(transcript)|go:"GO:0002250"(adaptive immune response)|go:"GO:0002323"(natural killer cell activation involved in immune response)|go:"GO:0005886"(plasma membrane)|go:"GO:0007165"(signal transduction)|go:"GO:0009897"(external side of plasma membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0032729"(positive regulation of interferon-gamma production)|go:"GO:0032757"(positive regulation of interleukin-8 production)|go:"GO:0038023"(signaling receptor activity)|go:"GO:0042288"(MHC class I protein binding)|go:"GO:0045087"(innate immune response)|go:"GO:0060732"(positive regulation of inositol phosphate biosynthetic process)|go:"GO:0071663"(positive regulation of granzyme B production)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR024303|interpro:IPR024304|interpro:IPR036179|reactome:R-HSA-202733 - - - figure legend:3C|dataset:Virus - Publications including interactions involving viral proteins|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2020/09/30 2020/10/06 rogid:gouXSFq22QLERoidFm6ju2SwoIE211044 rogid:QORMx+ZJyNjvraEeZH1rBgcD2bU9606 rigid:mjWJ76Qg8jYg5HBUnppHx9728no false fc-igg tag:?-?|biotin tag:?-? fc-igg tag:?-?|sufficient binding region:1-? - - psi-mi:"MI:0866"(tag visualisation) psi-mi:"MI:0866"(tag visualisation)