#ID(s) interactor A ID(s) interactor B Alt. ID(s) interactor A Alt. ID(s) interactor B Alias(es) interactor A Alias(es) interactor B Interaction detection method(s) Publication 1st author(s) Publication Identifier(s) Taxid interactor A Taxid interactor B Interaction type(s) Source database(s) Interaction identifier(s) Confidence value(s) Expansion method(s) Biological role(s) interactor A Biological role(s) interactor B Experimental role(s) interactor A Experimental role(s) interactor B Type(s) interactor A Type(s) interactor B Xref(s) interactor A Xref(s) interactor B Interaction Xref(s) Annotation(s) interactor A Annotation(s) interactor B Interaction annotation(s) Host organism(s) Interaction parameter(s) Creation date Update date Checksum(s) interactor A Checksum(s) interactor B Interaction Checksum(s) Negative Feature(s) interactor A Feature(s) interactor B Stoichiometry(s) interactor A Stoichiometry(s) interactor B Identification method participant A Identification method participant B uniprotkb:Q1LZX8 uniprotkb:P59594 intact:EBI-25487316 intact:EBI-15582614|intact:EBI-16063777|uniprotkb:Q6QU82|uniprotkb:Q7T696|uniprotkb:Q7TA19|uniprotkb:Q7TFA2|uniprotkb:Q7TFB1|uniprotkb:Q80BV6 psi-mi:q1lzx8_chlae(display_long)|uniprotkb:ACE2(gene name)|psi-mi:ACE2(display_short) psi-mi:spike_sars(display_long)|uniprotkb:S(gene name)|psi-mi:S(display_short)|uniprotkb:E2(gene name synonym)|uniprotkb:Peplomer protein(gene name synonym)|uniprotkb:2(orf name) psi-mi:"MI:0030"(cross-linking study) Yu et al. (2016) pubmed:26801988|imex:IM-27825 taxid:9534(chlae)|taxid:9534(Chlorocebus aethiops) taxid:694009(sars-cov)|taxid:694009(Human SARS coronavirus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-25493436|imex:IM-27825-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0004180"(carboxypeptidase activity)|go:"GO:0005576"(extracellular region)|go:"GO:0005737"(cytoplasm)|go:"GO:0005929"(cilium)|go:"GO:0008237"(metallopeptidase activity)|go:"GO:0008241"(peptidyl-dipeptidase activity)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0046872"(metal ion binding)|interpro:IPR031588|interpro:IPR001548(Peptidase M2, peptidyl-dipeptidase A) go:"GO:0005788"(endoplasmic reticulum lumen)|go:"GO:0005793"(endoplasmic reticulum-Golgi intermediate compartment)|go:"GO:0016021"(integral component of membrane)|go:"GO:0019031"(viral envelope)|go:"GO:0019064"(fusion of virus membrane with host plasma membrane)|go:"GO:0020002"(host cell plasma membrane)|go:"GO:0030666"(endocytic vesicle membrane)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039587"(suppression by virus of host tetherin activity)|go:"GO:0039654"(fusion of virus membrane with host endosome membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0044173"(host cell endoplasmic reticulum-Golgi intermediate compartment membrane)|go:"GO:0046789"(host cell surface receptor binding)|go:"GO:0046813"(receptor-mediated virion attachment to host cell)|go:"GO:0055036"(virion membrane)|go:"GO:0075509"(endocytosis involved in viral entry into host cell)|interpro:IPR002552(Coronavirus S2 glycoprotein)|interpro:IPR018548|interpro:IPR032500|interpro:IPR036326|interpro:IPR042578|interpro:IPR043002|interpro:IPR043473|interpro:IPR043607|interpro:IPR044341|interpro:IPR044370|interpro:IPR044873|interpro:IPR044874|rcsb pdb:1Q4Z|rcsb pdb:1T7G|rcsb pdb:1U4K|rcsb pdb:1WNC|rcsb pdb:1WYY|rcsb pdb:1XJP|rcsb pdb:1ZV7|rcsb pdb:1ZV8|rcsb pdb:1ZVB|rcsb pdb:2AJF|rcsb pdb:2BEQ|rcsb pdb:2BEZ|rcsb pdb:2DD8|rcsb pdb:2FXP|rcsb pdb:2GHV|rcsb pdb:2GHW|rcsb pdb:2RUM|rcsb pdb:2RUN|rcsb pdb:2RUO|rcsb pdb:3BGF|rcsb pdb:3D0G|rcsb pdb:3D0H|rcsb pdb:3D0I|rcsb pdb:3SCI|rcsb pdb:3SCJ|rcsb pdb:3SCK|rcsb pdb:3SCL|rcsb pdb:5WRG|rcsb pdb:5X4S|rcsb pdb:5X58|rcsb pdb:5X5B|rcsb pdb:5XJK|rcsb pdb:5XLR|rcsb pdb:5ZVM|rcsb pdb:6ACC|rcsb pdb:6ACD|rcsb pdb:6ACG|rcsb pdb:6ACK|rcsb pdb:6CRV|rcsb pdb:6CRW|rcsb pdb:6CRX|rcsb pdb:6CRZ|rcsb pdb:6CS0|rcsb pdb:6CS1|rcsb pdb:6CS2|rcsb pdb:6M3W|rcsb pdb:6NB6|rcsb pdb:6NB7|rcsb pdb:6VW1|rcsb pdb:6WAQ|rcsb pdb:7JN5|rcsb pdb:6ACJ|dip:DIP-29105N|reactome:R-HSA-9679509|reactome:R-HSA-9683686|reactome:R-HSA-9683701|refseq:NP_828851.1|reactome:R-HSA-9678110 - - - figure legend:Fig. 1|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9534(chlae-vero_e6)|taxid:9534(chlae-vero_e6 cells) - 2020/03/25 2020/04/09 rogid:vh4QBtvXTzIcH1l7zPHi10xs2ng9534 rogid:H4uZUhfNNQNcF4O+7CmC50IoAi8694009 rigid:oWpL+3WneN90N/8IqdXONfjEBXg false - v5 tag:?-? - - psi-mi:"MI:0817"(molecular weight estimation by silver staining) psi-mi:"MI:0817"(molecular weight estimation by silver staining) uniprotkb:Q1LZX8 uniprotkb:P84198 intact:EBI-25487316 intact:EBI-457639|uniprotkb:Q3HWE4 psi-mi:q1lzx8_chlae(display_long)|uniprotkb:ACE2(gene name)|psi-mi:ACE2(display_short) psi-mi:vime_chlae(display_long)|uniprotkb:VIM(gene name)|psi-mi:VIM(display_short) psi-mi:"MI:0030"(cross-linking study) Yu et al. (2016) pubmed:26801988|imex:IM-27825 taxid:9534(chlae)|taxid:9534(Chlorocebus aethiops) taxid:9534(chlae)|taxid:9534(Chlorocebus aethiops) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-25493436|imex:IM-27825-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0004180"(carboxypeptidase activity)|go:"GO:0005576"(extracellular region)|go:"GO:0005737"(cytoplasm)|go:"GO:0005929"(cilium)|go:"GO:0008237"(metallopeptidase activity)|go:"GO:0008241"(peptidyl-dipeptidase activity)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0046872"(metal ion binding)|interpro:IPR031588|interpro:IPR001548(Peptidase M2, peptidyl-dipeptidase A) interpro:IPR006821(Intermediate filament, DNA-binding region)|interpro:IPR018039|interpro:IPR039008|interpro:IPR027699|go:"GO:0005200"(structural constituent of cytoskeleton)|go:"GO:0005737"(cytoplasm)|go:"GO:0005882"(intermediate filament)|go:"GO:0005886"(plasma membrane)|go:"GO:0016363"(nuclear matrix)|go:"GO:0045109"(intermediate filament organization)|go:"GO:0071222"(cellular response to lipopolysaccharide)|go:"GO:0071225"(cellular response to muramyl dipeptide) - - - figure legend:Fig. 1|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9534(chlae-vero_e6)|taxid:9534(chlae-vero_e6 cells) - 2020/03/25 2020/04/09 rogid:vh4QBtvXTzIcH1l7zPHi10xs2ng9534 rogid:amTsBgBtmuPybOkclGtOBF8W3to9534 rigid:oWpL+3WneN90N/8IqdXONfjEBXg false - - - - psi-mi:"MI:0817"(molecular weight estimation by silver staining) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q1LZX8 uniprotkb:P84198 intact:EBI-25487316 intact:EBI-457639|uniprotkb:Q3HWE4 psi-mi:q1lzx8_chlae(display_long)|uniprotkb:ACE2(gene name)|psi-mi:ACE2(display_short) psi-mi:vime_chlae(display_long)|uniprotkb:VIM(gene name)|psi-mi:VIM(display_short) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Yu et al. (2016) pubmed:26801988|imex:IM-27825 taxid:9534(chlae)|taxid:9534(Chlorocebus aethiops) taxid:9534(chlae)|taxid:9534(Chlorocebus aethiops) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-25493590|imex:IM-27825-3 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0004180"(carboxypeptidase activity)|go:"GO:0005576"(extracellular region)|go:"GO:0005737"(cytoplasm)|go:"GO:0005929"(cilium)|go:"GO:0008237"(metallopeptidase activity)|go:"GO:0008241"(peptidyl-dipeptidase activity)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0046872"(metal ion binding)|interpro:IPR031588|interpro:IPR001548(Peptidase M2, peptidyl-dipeptidase A) interpro:IPR006821(Intermediate filament, DNA-binding region)|interpro:IPR018039|interpro:IPR039008|interpro:IPR027699|go:"GO:0005200"(structural constituent of cytoskeleton)|go:"GO:0005737"(cytoplasm)|go:"GO:0005882"(intermediate filament)|go:"GO:0005886"(plasma membrane)|go:"GO:0016363"(nuclear matrix)|go:"GO:0045109"(intermediate filament organization)|go:"GO:0071222"(cellular response to lipopolysaccharide)|go:"GO:0071225"(cellular response to muramyl dipeptide) - - - figure legend:Fig. 2|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9534(chlae-vero_e6)|taxid:9534(chlae-vero_e6 cells) - 2020/03/25 2020/04/09 rogid:vh4QBtvXTzIcH1l7zPHi10xs2ng9534 rogid:amTsBgBtmuPybOkclGtOBF8W3to9534 rigid:oWpL+3WneN90N/8IqdXONfjEBXg false - - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:Q1LZX8 uniprotkb:P59594 intact:EBI-25487316 intact:EBI-15582614|intact:EBI-16063777|uniprotkb:Q6QU82|uniprotkb:Q7T696|uniprotkb:Q7TA19|uniprotkb:Q7TFA2|uniprotkb:Q7TFB1|uniprotkb:Q80BV6 psi-mi:q1lzx8_chlae(display_long)|uniprotkb:ACE2(gene name)|psi-mi:ACE2(display_short) psi-mi:spike_sars(display_long)|uniprotkb:S(gene name)|psi-mi:S(display_short)|uniprotkb:E2(gene name synonym)|uniprotkb:Peplomer protein(gene name synonym)|uniprotkb:2(orf name) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Yu et al. (2016) pubmed:26801988|imex:IM-27825 taxid:9534(chlae)|taxid:9534(Chlorocebus aethiops) taxid:694009(sars-cov)|taxid:694009(Human SARS coronavirus) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-25493590|imex:IM-27825-3 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0004180"(carboxypeptidase activity)|go:"GO:0005576"(extracellular region)|go:"GO:0005737"(cytoplasm)|go:"GO:0005929"(cilium)|go:"GO:0008237"(metallopeptidase activity)|go:"GO:0008241"(peptidyl-dipeptidase activity)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0046872"(metal ion binding)|interpro:IPR031588|interpro:IPR001548(Peptidase M2, peptidyl-dipeptidase A) go:"GO:0005788"(endoplasmic reticulum lumen)|go:"GO:0005793"(endoplasmic reticulum-Golgi intermediate compartment)|go:"GO:0016021"(integral component of membrane)|go:"GO:0019031"(viral envelope)|go:"GO:0019064"(fusion of virus membrane with host plasma membrane)|go:"GO:0020002"(host cell plasma membrane)|go:"GO:0030666"(endocytic vesicle membrane)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039587"(suppression by virus of host tetherin activity)|go:"GO:0039654"(fusion of virus membrane with host endosome membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0044173"(host cell endoplasmic reticulum-Golgi intermediate compartment membrane)|go:"GO:0046789"(host cell surface receptor binding)|go:"GO:0046813"(receptor-mediated virion attachment to host cell)|go:"GO:0055036"(virion membrane)|go:"GO:0075509"(endocytosis involved in viral entry into host cell)|interpro:IPR002552(Coronavirus S2 glycoprotein)|interpro:IPR018548|interpro:IPR032500|interpro:IPR036326|interpro:IPR042578|interpro:IPR043002|interpro:IPR043473|interpro:IPR043607|interpro:IPR044341|interpro:IPR044370|interpro:IPR044873|interpro:IPR044874|rcsb pdb:1Q4Z|rcsb pdb:1T7G|rcsb pdb:1U4K|rcsb pdb:1WNC|rcsb pdb:1WYY|rcsb pdb:1XJP|rcsb pdb:1ZV7|rcsb pdb:1ZV8|rcsb pdb:1ZVB|rcsb pdb:2AJF|rcsb pdb:2BEQ|rcsb pdb:2BEZ|rcsb pdb:2DD8|rcsb pdb:2FXP|rcsb pdb:2GHV|rcsb pdb:2GHW|rcsb pdb:2RUM|rcsb pdb:2RUN|rcsb pdb:2RUO|rcsb pdb:3BGF|rcsb pdb:3D0G|rcsb pdb:3D0H|rcsb pdb:3D0I|rcsb pdb:3SCI|rcsb pdb:3SCJ|rcsb pdb:3SCK|rcsb pdb:3SCL|rcsb pdb:5WRG|rcsb pdb:5X4S|rcsb pdb:5X58|rcsb pdb:5X5B|rcsb pdb:5XJK|rcsb pdb:5XLR|rcsb pdb:5ZVM|rcsb pdb:6ACC|rcsb pdb:6ACD|rcsb pdb:6ACG|rcsb pdb:6ACK|rcsb pdb:6CRV|rcsb pdb:6CRW|rcsb pdb:6CRX|rcsb pdb:6CRZ|rcsb pdb:6CS0|rcsb pdb:6CS1|rcsb pdb:6CS2|rcsb pdb:6M3W|rcsb pdb:6NB6|rcsb pdb:6NB7|rcsb pdb:6VW1|rcsb pdb:6WAQ|rcsb pdb:7JN5|rcsb pdb:6ACJ|dip:DIP-29105N|reactome:R-HSA-9679509|reactome:R-HSA-9683686|reactome:R-HSA-9683701|refseq:NP_828851.1|reactome:R-HSA-9678110 - - - figure legend:Fig. 2|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9534(chlae-vero_e6)|taxid:9534(chlae-vero_e6 cells) - 2020/03/25 2020/04/09 rogid:vh4QBtvXTzIcH1l7zPHi10xs2ng9534 rogid:H4uZUhfNNQNcF4O+7CmC50IoAi8694009 rigid:oWpL+3WneN90N/8IqdXONfjEBXg false - v5 tag:?-? - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:P84198 uniprotkb:P59594 intact:EBI-457639|uniprotkb:Q3HWE4 intact:EBI-15582614|intact:EBI-16063777|uniprotkb:Q6QU82|uniprotkb:Q7T696|uniprotkb:Q7TA19|uniprotkb:Q7TFA2|uniprotkb:Q7TFB1|uniprotkb:Q80BV6 psi-mi:vime_chlae(display_long)|uniprotkb:VIM(gene name)|psi-mi:VIM(display_short) psi-mi:spike_sars(display_long)|uniprotkb:S(gene name)|psi-mi:S(display_short)|uniprotkb:E2(gene name synonym)|uniprotkb:Peplomer protein(gene name synonym)|uniprotkb:2(orf name) psi-mi:"MI:0047"(far western blotting) Yu et al. (2016) pubmed:26801988|imex:IM-27825 taxid:9534(chlae)|taxid:9534(Chlorocebus aethiops) taxid:694009(sars-cov)|taxid:694009(Human SARS coronavirus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-25493619|imex:IM-27825-5 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR006821(Intermediate filament, DNA-binding region)|interpro:IPR018039|interpro:IPR039008|interpro:IPR027699|go:"GO:0005200"(structural constituent of cytoskeleton)|go:"GO:0005737"(cytoplasm)|go:"GO:0005882"(intermediate filament)|go:"GO:0005886"(plasma membrane)|go:"GO:0016363"(nuclear matrix)|go:"GO:0045109"(intermediate filament organization)|go:"GO:0071222"(cellular response to lipopolysaccharide)|go:"GO:0071225"(cellular response to muramyl dipeptide) go:"GO:0005788"(endoplasmic reticulum lumen)|go:"GO:0005793"(endoplasmic reticulum-Golgi intermediate compartment)|go:"GO:0016021"(integral component of membrane)|go:"GO:0019031"(viral envelope)|go:"GO:0019064"(fusion of virus membrane with host plasma membrane)|go:"GO:0020002"(host cell plasma membrane)|go:"GO:0030666"(endocytic vesicle membrane)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039587"(suppression by virus of host tetherin activity)|go:"GO:0039654"(fusion of virus membrane with host endosome membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0044173"(host cell endoplasmic reticulum-Golgi intermediate compartment membrane)|go:"GO:0046789"(host cell surface receptor binding)|go:"GO:0046813"(receptor-mediated virion attachment to host cell)|go:"GO:0055036"(virion membrane)|go:"GO:0075509"(endocytosis involved in viral entry into host cell)|interpro:IPR002552(Coronavirus S2 glycoprotein)|interpro:IPR018548|interpro:IPR032500|interpro:IPR036326|interpro:IPR042578|interpro:IPR043002|interpro:IPR043473|interpro:IPR043607|interpro:IPR044341|interpro:IPR044370|interpro:IPR044873|interpro:IPR044874|rcsb pdb:1Q4Z|rcsb pdb:1T7G|rcsb pdb:1U4K|rcsb pdb:1WNC|rcsb pdb:1WYY|rcsb pdb:1XJP|rcsb pdb:1ZV7|rcsb pdb:1ZV8|rcsb pdb:1ZVB|rcsb pdb:2AJF|rcsb pdb:2BEQ|rcsb pdb:2BEZ|rcsb pdb:2DD8|rcsb pdb:2FXP|rcsb pdb:2GHV|rcsb pdb:2GHW|rcsb pdb:2RUM|rcsb pdb:2RUN|rcsb pdb:2RUO|rcsb pdb:3BGF|rcsb pdb:3D0G|rcsb pdb:3D0H|rcsb pdb:3D0I|rcsb pdb:3SCI|rcsb pdb:3SCJ|rcsb pdb:3SCK|rcsb pdb:3SCL|rcsb pdb:5WRG|rcsb pdb:5X4S|rcsb pdb:5X58|rcsb pdb:5X5B|rcsb pdb:5XJK|rcsb pdb:5XLR|rcsb pdb:5ZVM|rcsb pdb:6ACC|rcsb pdb:6ACD|rcsb pdb:6ACG|rcsb pdb:6ACK|rcsb pdb:6CRV|rcsb pdb:6CRW|rcsb pdb:6CRX|rcsb pdb:6CRZ|rcsb pdb:6CS0|rcsb pdb:6CS1|rcsb pdb:6CS2|rcsb pdb:6M3W|rcsb pdb:6NB6|rcsb pdb:6NB7|rcsb pdb:6VW1|rcsb pdb:6WAQ|rcsb pdb:7JN5|rcsb pdb:6ACJ|dip:DIP-29105N|reactome:R-HSA-9679509|reactome:R-HSA-9683686|reactome:R-HSA-9683701|refseq:NP_828851.1|reactome:R-HSA-9678110 - - - figure legend:Fig. 5a|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2020/03/25 2020/04/09 rogid:amTsBgBtmuPybOkclGtOBF8W3to9534 rogid:H4uZUhfNNQNcF4O+7CmC50IoAi8694009 rigid:YtjPxhHI4fIzmyzfLC4634UQLqw false - v5 tag:c-c|his tag:c-c - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:P84198 uniprotkb:P59594 intact:EBI-457639|uniprotkb:Q3HWE4 intact:EBI-15582614|intact:EBI-16063777|uniprotkb:Q6QU82|uniprotkb:Q7T696|uniprotkb:Q7TA19|uniprotkb:Q7TFA2|uniprotkb:Q7TFB1|uniprotkb:Q80BV6 psi-mi:vime_chlae(display_long)|uniprotkb:VIM(gene name)|psi-mi:VIM(display_short) psi-mi:spike_sars(display_long)|uniprotkb:S(gene name)|psi-mi:S(display_short)|uniprotkb:E2(gene name synonym)|uniprotkb:Peplomer protein(gene name synonym)|uniprotkb:2(orf name) psi-mi:"MI:0663"(confocal microscopy) Yu et al. (2016) pubmed:26801988|imex:IM-27825 taxid:9534(chlae)|taxid:9534(Chlorocebus aethiops) taxid:694009(sars-cov)|taxid:694009(Human SARS coronavirus) psi-mi:"MI:0403"(colocalization) psi-mi:"MI:0469"(IntAct) intact:EBI-25493653|imex:IM-27825-7 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR006821(Intermediate filament, DNA-binding region)|interpro:IPR018039|interpro:IPR039008|interpro:IPR027699|go:"GO:0005200"(structural constituent of cytoskeleton)|go:"GO:0005737"(cytoplasm)|go:"GO:0005882"(intermediate filament)|go:"GO:0005886"(plasma membrane)|go:"GO:0016363"(nuclear matrix)|go:"GO:0045109"(intermediate filament organization)|go:"GO:0071222"(cellular response to lipopolysaccharide)|go:"GO:0071225"(cellular response to muramyl dipeptide) go:"GO:0005788"(endoplasmic reticulum lumen)|go:"GO:0005793"(endoplasmic reticulum-Golgi intermediate compartment)|go:"GO:0016021"(integral component of membrane)|go:"GO:0019031"(viral envelope)|go:"GO:0019064"(fusion of virus membrane with host plasma membrane)|go:"GO:0020002"(host cell plasma membrane)|go:"GO:0030666"(endocytic vesicle membrane)|go:"GO:0039502"(suppression by virus of host type I interferon-mediated signaling pathway)|go:"GO:0039587"(suppression by virus of host tetherin activity)|go:"GO:0039654"(fusion of virus membrane with host endosome membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0044173"(host cell endoplasmic reticulum-Golgi intermediate compartment membrane)|go:"GO:0046789"(host cell surface receptor binding)|go:"GO:0046813"(receptor-mediated virion attachment to host cell)|go:"GO:0055036"(virion membrane)|go:"GO:0075509"(endocytosis involved in viral entry into host cell)|interpro:IPR002552(Coronavirus S2 glycoprotein)|interpro:IPR018548|interpro:IPR032500|interpro:IPR036326|interpro:IPR042578|interpro:IPR043002|interpro:IPR043473|interpro:IPR043607|interpro:IPR044341|interpro:IPR044370|interpro:IPR044873|interpro:IPR044874|rcsb pdb:1Q4Z|rcsb pdb:1T7G|rcsb pdb:1U4K|rcsb pdb:1WNC|rcsb pdb:1WYY|rcsb pdb:1XJP|rcsb pdb:1ZV7|rcsb pdb:1ZV8|rcsb pdb:1ZVB|rcsb pdb:2AJF|rcsb pdb:2BEQ|rcsb pdb:2BEZ|rcsb pdb:2DD8|rcsb pdb:2FXP|rcsb pdb:2GHV|rcsb pdb:2GHW|rcsb pdb:2RUM|rcsb pdb:2RUN|rcsb pdb:2RUO|rcsb pdb:3BGF|rcsb pdb:3D0G|rcsb pdb:3D0H|rcsb pdb:3D0I|rcsb pdb:3SCI|rcsb pdb:3SCJ|rcsb pdb:3SCK|rcsb pdb:3SCL|rcsb pdb:5WRG|rcsb pdb:5X4S|rcsb pdb:5X58|rcsb pdb:5X5B|rcsb pdb:5XJK|rcsb pdb:5XLR|rcsb pdb:5ZVM|rcsb pdb:6ACC|rcsb pdb:6ACD|rcsb pdb:6ACG|rcsb pdb:6ACK|rcsb pdb:6CRV|rcsb pdb:6CRW|rcsb pdb:6CRX|rcsb pdb:6CRZ|rcsb pdb:6CS0|rcsb pdb:6CS1|rcsb pdb:6CS2|rcsb pdb:6M3W|rcsb pdb:6NB6|rcsb pdb:6NB7|rcsb pdb:6VW1|rcsb pdb:6WAQ|rcsb pdb:7JN5|rcsb pdb:6ACJ|dip:DIP-29105N|reactome:R-HSA-9679509|reactome:R-HSA-9683686|reactome:R-HSA-9683701|refseq:NP_828851.1|reactome:R-HSA-9678110 go:"GO:0009986"(cell surface) - - figure legend:Fig. 3|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9534(chlae-vero_e6)|taxid:9534(chlae-vero_e6 cells) - 2020/03/25 2020/04/09 rogid:amTsBgBtmuPybOkclGtOBF8W3to9534 rogid:H4uZUhfNNQNcF4O+7CmC50IoAi8694009 rigid:YtjPxhHI4fIzmyzfLC4634UQLqw false - v5 tag:?-? - - psi-mi:"MI:0422"(immunostaining) psi-mi:"MI:0422"(immunostaining)