#ID(s) interactor A ID(s) interactor B Alt. ID(s) interactor A Alt. ID(s) interactor B Alias(es) interactor A Alias(es) interactor B Interaction detection method(s) Publication 1st author(s) Publication Identifier(s) Taxid interactor A Taxid interactor B Interaction type(s) Source database(s) Interaction identifier(s) Confidence value(s) Expansion method(s) Biological role(s) interactor A Biological role(s) interactor B Experimental role(s) interactor A Experimental role(s) interactor B Type(s) interactor A Type(s) interactor B Xref(s) interactor A Xref(s) interactor B Interaction Xref(s) Annotation(s) interactor A Annotation(s) interactor B Interaction annotation(s) Host organism(s) Interaction parameter(s) Creation date Update date Checksum(s) interactor A Checksum(s) interactor B Interaction Checksum(s) Negative Feature(s) interactor A Feature(s) interactor B Stoichiometry(s) interactor A Stoichiometry(s) interactor B Identification method participant A Identification method participant B uniprotkb:P16298-4 uniprotkb:Q96SQ7-1 intact:EBI-26442038|ensembl:ENSP00000378306 intact:EBI-26429573|ensembl:ENSP00000304676 psi-mi:p16298-4(display_long)|uniprotkb:PPP3CB(gene name)|psi-mi:PPP3CB(display_short)|uniprotkb:CALNA2(gene name synonym)|uniprotkb:CALNB(gene name synonym)|uniprotkb:CNA2(gene name synonym)|uniprotkb:CAM-PRP catalytic subunit(gene name synonym)|uniprotkb:Calmodulin-dependent calcineurin A subunit beta isoform(gene name synonym) psi-mi:q96sq7-1(display_long)|uniprotkb:ATOH8(gene name)|psi-mi:ATOH8(display_short)|uniprotkb:ATH6(gene name synonym)|uniprotkb:BHLHA21(gene name synonym)|uniprotkb:Class A basic helix-loop-helix protein 21(gene name synonym)|uniprotkb:Helix-loop-helix protein hATH-6(gene name synonym) psi-mi:"MI:0055"(fluorescent resonance energy transfer) Chen et al. (2016) imex:IM-28461|pubmed:26496921 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:2364"(proximity) psi-mi:"MI:0486"(UniProt) intact:EBI-26429581|imex:IM-28461-1 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0584"(fluorescence acceptor) psi-mi:"MI:0583"(fluorescence donor) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-1759540(isoform-parent)|uniprotkb:P16298-4(isoform-parent)|ensembl:ENSG00000107758(gene)|ensembl:ENST00000394829(transcript) ensembl:ENSG00000168874(gene)|ensembl:ENST00000306279(transcript)|intact:EBI-3916470(isoform-parent) - - - figure legend:Fig. 3|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/10/27 2020/11/04 rogid:DW31UV3Jo673w3oSAX1K3u4KpUc9606 rogid:Zir7yvonqPNivKl57JF1k/RQPes9606 rigid:X9mnGEzVTXwpjYlRFh/IhGhoXcI false enhanced yellow fluorescent protein tag:n-n cyan fluorescent protein tag:c-c - - psi-mi:"MI:0867"(tag visualisation by fluorescence) psi-mi:"MI:0867"(tag visualisation by fluorescence) uniprotkb:P16298 uniprotkb:Q96SQ7 intact:EBI-1759540|uniprotkb:P16299|uniprotkb:Q8N3W4|uniprotkb:Q5F2F9|uniprotkb:Q8N1F0|ensembl:ENSP00000353881 intact:EBI-3916470|uniprotkb:Q504S2|uniprotkb:Q659B0|intact:EBI-28987858|ensembl:ENSP00000304676 psi-mi:pp2bb_human(display_long)|uniprotkb:PPP3CB(gene name)|psi-mi:PPP3CB(display_short)|uniprotkb:CALNA2(gene name synonym)|uniprotkb:CALNB(gene name synonym)|uniprotkb:CNA2(gene name synonym)|uniprotkb:Calmodulin-dependent calcineurin A subunit beta isoform(gene name synonym)|uniprotkb:CAM-PRP catalytic subunit(gene name synonym) psi-mi:atoh8_human(display_long)|uniprotkb:ATOH8(gene name)|psi-mi:ATOH8(display_short)|uniprotkb:ATH6(gene name synonym)|uniprotkb:BHLHA21(gene name synonym)|uniprotkb:Class A basic helix-loop-helix protein 21(gene name synonym)|uniprotkb:Helix-loop-helix protein hATH-6(gene name synonym) psi-mi:"MI:0416"(fluorescence microscopy) Chen et al. (2016) imex:IM-28461|pubmed:26496921 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0403"(colocalization) psi-mi:"MI:0486"(UniProt) intact:EBI-26429594|imex:IM-28461-3 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001135826.1|refseq:NP_066955.1|refseq:NP_001276897.1|refseq:NP_001276898.1|refseq:NP_001135825.1|dip:DIP-52337N|ensembl:ENSG00000107758(gene)|ensembl:ENST00000360663(transcript)|go:"GO:0001915"(negative regulation of T cell mediated cytotoxicity)|go:"GO:0001946"(lymphangiogenesis)|go:"GO:0004722"(protein serine/threonine phosphatase activity)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005955"(calcineurin complex)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0006470"(protein dephosphorylation)|go:"GO:0007165"(signal transduction)|go:"GO:0007507"(heart development)|go:"GO:0007612"(learning)|go:"GO:0007613"(memory)|go:"GO:0016311"(dephosphorylation)|go:"GO:0017156"(calcium-ion regulated exocytosis)|go:"GO:0019899"(enzyme binding)|go:"GO:0030018"(Z disc)|go:"GO:0030217"(T cell differentiation)|go:"GO:0030315"(T-tubule)|go:"GO:0030346"(protein phosphatase 2B binding)|go:"GO:0031987"(locomotion involved in locomotory behavior)|go:"GO:0033173"(calcineurin-NFAT signaling cascade)|go:"GO:0033192"(calmodulin-dependent protein phosphatase activity)|go:"GO:0034097"(response to cytokine)|go:"GO:0035774"(positive regulation of insulin secretion involved in cellular response to glucose stimulus)|go:"GO:0042098"(T cell proliferation)|go:"GO:0042110"(T cell activation)|go:"GO:0043029"(T cell homeostasis)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046983"(protein dimerization activity)|go:"GO:0048167"(regulation of synaptic plasticity)|go:"GO:0048675"(axon extension)|go:"GO:0050796"(regulation of insulin secretion)|go:"GO:0097720"(calcineurin-mediated signaling)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0106306"|go:"GO:0106307"|go:"GO:1900242"(regulation of synaptic vesicle endocytosis)|interpro:IPR004843(Metallophosphoesterase)|interpro:IPR006186("Serine/threonine-specific protein phosphatase and bis(5-nucleosyl)-tetraphosphatase")|interpro:IPR029052|interpro:IPR041751|interpro:IPR043360|mint:P16298|rcsb pdb:4OR9|rcsb pdb:4ORA|rcsb pdb:4ORC|reactome:R-HSA-180024|reactome:R-HSA-2025928|reactome:R-HSA-2871809|reactome:R-HSA-4086398|reactome:R-HSA-5607763|reactome:R-HSA-9010642 refseq:NP_116216.2|ensembl:ENSP00000304676|go:"GO:0030182"(neuron differentiation)|go:"GO:0035148"(tube formation)|go:"GO:0045603"(positive regulation of endothelial cell differentiation)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0046983"(protein dimerization activity)|go:"GO:0051450"(myoblast proliferation)|go:"GO:0060395"(SMAD protein signal transduction)|go:"GO:0070888"(E-box binding)|go:"GO:0140297"(DNA-binding transcription factor binding)|go:"GO:1902895"(positive regulation of miRNA transcription)|interpro:IPR011598(Helix-loop-helix DNA-binding)|interpro:IPR032660|interpro:IPR036638|go:"GO:0016607"(nuclear speck)|ensembl:ENSG00000168874(gene)|ensembl:ENST00000306279(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001704"(formation of primary germ layer)|go:"GO:0001937"(negative regulation of endothelial cell proliferation)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0010595"(positive regulation of endothelial cell migration)|go:"GO:0010629"(negative regulation of gene expression) go:"GO:0005737"(cytoplasm) - - figure legend:Fig. 2A-D|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/10/27 2020/10/27 rogid:Uy2qO3SYsZxr7CUwepgM6QCplgM9606 rogid:Zir7yvonqPNivKl57JF1k/RQPes9606 rigid:EfrsGAg/NqE/aBrprhCtKITpuV8 false - - - - psi-mi:"MI:1200"(immunocytochemistry) psi-mi:"MI:1200"(immunocytochemistry) uniprotkb:P16298-4 uniprotkb:Q96SQ7-1 intact:EBI-26442038|ensembl:ENSP00000378306 intact:EBI-26429573|ensembl:ENSP00000304676 psi-mi:p16298-4(display_long)|uniprotkb:PPP3CB(gene name)|psi-mi:PPP3CB(display_short)|uniprotkb:CALNA2(gene name synonym)|uniprotkb:CALNB(gene name synonym)|uniprotkb:CNA2(gene name synonym)|uniprotkb:CAM-PRP catalytic subunit(gene name synonym)|uniprotkb:Calmodulin-dependent calcineurin A subunit beta isoform(gene name synonym) psi-mi:q96sq7-1(display_long)|uniprotkb:ATOH8(gene name)|psi-mi:ATOH8(display_short)|uniprotkb:ATH6(gene name synonym)|uniprotkb:BHLHA21(gene name synonym)|uniprotkb:Class A basic helix-loop-helix protein 21(gene name synonym)|uniprotkb:Helix-loop-helix protein hATH-6(gene name synonym) psi-mi:"MI:0096"(pull down) Chen et al. (2016) imex:IM-28461|pubmed:26496921 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0486"(UniProt) intact:EBI-26429613|imex:IM-28461-5 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-1759540(isoform-parent)|uniprotkb:P16298-4(isoform-parent)|ensembl:ENSG00000107758(gene)|ensembl:ENST00000394829(transcript) ensembl:ENSG00000168874(gene)|ensembl:ENST00000306279(transcript)|intact:EBI-3916470(isoform-parent) - - - figure legend:Fig. 4A, 7,8,9,10|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2020/10/27 2020/11/04 rogid:DW31UV3Jo673w3oSAX1K3u4KpUc9606 rogid:Zir7yvonqPNivKl57JF1k/RQPes9606 rigid:X9mnGEzVTXwpjYlRFh/IhGhoXcI false glutathione s tranferase tag:n-n|sufficient binding region:81-401 cyan fluorescent protein tag:c-c|sufficient binding region:1-55|sufficient binding region:225-275(IPR011598) - - psi-mi:"MI:0705"(anti tag western blot) psi-mi:"MI:0705"(anti tag western blot) uniprotkb:P16298-4 uniprotkb:Q96SQ7-1 intact:EBI-26442038|ensembl:ENSP00000378306 intact:EBI-26429573|ensembl:ENSP00000304676 psi-mi:p16298-4(display_long)|uniprotkb:PPP3CB(gene name)|psi-mi:PPP3CB(display_short)|uniprotkb:CALNA2(gene name synonym)|uniprotkb:CALNB(gene name synonym)|uniprotkb:CNA2(gene name synonym)|uniprotkb:CAM-PRP catalytic subunit(gene name synonym)|uniprotkb:Calmodulin-dependent calcineurin A subunit beta isoform(gene name synonym) psi-mi:q96sq7-1(display_long)|uniprotkb:ATOH8(gene name)|psi-mi:ATOH8(display_short)|uniprotkb:ATH6(gene name synonym)|uniprotkb:BHLHA21(gene name synonym)|uniprotkb:Class A basic helix-loop-helix protein 21(gene name synonym)|uniprotkb:Helix-loop-helix protein hATH-6(gene name synonym) psi-mi:"MI:0096"(pull down) Chen et al. (2016) imex:IM-28461|pubmed:26496921 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0486"(UniProt) intact:EBI-26429622|imex:IM-28461-7 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-1759540(isoform-parent)|uniprotkb:P16298-4(isoform-parent)|ensembl:ENSG00000107758(gene)|ensembl:ENST00000394829(transcript) ensembl:ENSG00000168874(gene)|ensembl:ENST00000306279(transcript)|intact:EBI-3916470(isoform-parent) - - - figure legend:Fig. 4B, 6B|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2020/10/27 2020/11/04 rogid:DW31UV3Jo673w3oSAX1K3u4KpUc9606 rogid:Zir7yvonqPNivKl57JF1k/RQPes9606 rigid:X9mnGEzVTXwpjYlRFh/IhGhoXcI false enhanced yellow fluorescent protein tag:n-n glutathione s tranferase tag:n-n - - psi-mi:"MI:0705"(anti tag western blot) psi-mi:"MI:0705"(anti tag western blot) uniprotkb:P48454 uniprotkb:Q96SQ7-1 intact:EBI-2827192|uniprotkb:Q9H4M5|uniprotkb:Q9BSS6|uniprotkb:B4DRT5|ensembl:ENSP00000240139 intact:EBI-26429573|ensembl:ENSP00000304676 psi-mi:pp2bc_human(display_long)|uniprotkb:PPP3CC(gene name)|psi-mi:PPP3CC(display_short)|uniprotkb:CALNA3(gene name synonym)|uniprotkb:CNA3(gene name synonym)|uniprotkb:CAM-PRP catalytic subunit(gene name synonym)|uniprotkb:Calcineurin, testis-specific catalytic subunit(gene name synonym)|uniprotkb:Calmodulin-dependent calcineurin A subunit gamma isoform(gene name synonym) psi-mi:q96sq7-1(display_long)|uniprotkb:ATOH8(gene name)|psi-mi:ATOH8(display_short)|uniprotkb:ATH6(gene name synonym)|uniprotkb:BHLHA21(gene name synonym)|uniprotkb:Class A basic helix-loop-helix protein 21(gene name synonym)|uniprotkb:Helix-loop-helix protein hATH-6(gene name synonym) psi-mi:"MI:0096"(pull down) Chen et al. (2016) imex:IM-28461|pubmed:26496921 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0486"(UniProt) intact:EBI-26429650|imex:IM-28461-11 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_005596.2|refseq:NP_001230904.1|refseq:NP_001230903.1|ensembl:ENSG00000120910(gene)|ensembl:ENST00000240139(transcript)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005955"(calcineurin complex)|go:"GO:0006470"(protein dephosphorylation)|go:"GO:0007420"(brain development)|go:"GO:0033173"(calcineurin-NFAT signaling cascade)|go:"GO:0033192"(calmodulin-dependent protein phosphatase activity)|go:"GO:0046872"(metal ion binding)|go:"GO:0097720"(calcineurin-mediated signaling)|go:"GO:0098793"(presynapse)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0106306"|go:"GO:0106307"|go:"GO:1900244"(positive regulation of synaptic vesicle endocytosis)|interpro:IPR004843(Metallophosphoesterase)|interpro:IPR006186("Serine/threonine-specific protein phosphatase and bis(5-nucleosyl)-tetraphosphatase")|interpro:IPR029052|interpro:IPR041751|interpro:IPR043360|reactome:R-HSA-111447|reactome:R-HSA-180024 ensembl:ENSG00000168874(gene)|ensembl:ENST00000306279(transcript)|intact:EBI-3916470(isoform-parent) - - - figure legend:Fig. 6B|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2020/10/27 2020/10/27 rogid:kCGnmYnNPtbosNJTQdIZ9ye0JHk9606 rogid:Zir7yvonqPNivKl57JF1k/RQPes9606 rigid:ikNbelY3bLYl6Lu951OyKKBHdxg false enhanced yellow fluorescent protein tag:n-n|sufficient binding region:?-? glutathione s tranferase tag:n-n - - psi-mi:"MI:0705"(anti tag western blot) psi-mi:"MI:0705"(anti tag western blot) uniprotkb:P16298-4 uniprotkb:Q96SQ7-1 intact:EBI-26442038|ensembl:ENSP00000378306 intact:EBI-26429573|ensembl:ENSP00000304676 psi-mi:p16298-4(display_long)|uniprotkb:PPP3CB(gene name)|psi-mi:PPP3CB(display_short)|uniprotkb:CALNA2(gene name synonym)|uniprotkb:CALNB(gene name synonym)|uniprotkb:CNA2(gene name synonym)|uniprotkb:CAM-PRP catalytic subunit(gene name synonym)|uniprotkb:Calmodulin-dependent calcineurin A subunit beta isoform(gene name synonym) psi-mi:q96sq7-1(display_long)|uniprotkb:ATOH8(gene name)|psi-mi:ATOH8(display_short)|uniprotkb:ATH6(gene name synonym)|uniprotkb:BHLHA21(gene name synonym)|uniprotkb:Class A basic helix-loop-helix protein 21(gene name synonym)|uniprotkb:Helix-loop-helix protein hATH-6(gene name synonym) psi-mi:"MI:0096"(pull down) Chen et al. (2016) imex:IM-28461|pubmed:26496921 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0486"(UniProt) intact:EBI-26442047|imex:IM-28461-13 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-1759540(isoform-parent)|uniprotkb:P16298-4(isoform-parent)|ensembl:ENSG00000107758(gene)|ensembl:ENST00000394829(transcript) ensembl:ENSG00000168874(gene)|ensembl:ENST00000306279(transcript)|intact:EBI-3916470(isoform-parent) - - - figure legend:Fig. 6A|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2020/10/27 2020/11/04 rogid:DW31UV3Jo673w3oSAX1K3u4KpUc9606 rogid:Zir7yvonqPNivKl57JF1k/RQPes9606 rigid:X9mnGEzVTXwpjYlRFh/IhGhoXcI false enhanced yellow fluorescent protein tag:n-n glutathione s tranferase tag:n-n - - psi-mi:"MI:0705"(anti tag western blot) psi-mi:"MI:0705"(anti tag western blot) uniprotkb:P16298-4 uniprotkb:Q96SQ7-1 intact:EBI-26442038|ensembl:ENSP00000378306 intact:EBI-26429573|ensembl:ENSP00000304676 psi-mi:p16298-4(display_long)|uniprotkb:PPP3CB(gene name)|psi-mi:PPP3CB(display_short)|uniprotkb:CALNA2(gene name synonym)|uniprotkb:CALNB(gene name synonym)|uniprotkb:CNA2(gene name synonym)|uniprotkb:CAM-PRP catalytic subunit(gene name synonym)|uniprotkb:Calmodulin-dependent calcineurin A subunit beta isoform(gene name synonym) psi-mi:q96sq7-1(display_long)|uniprotkb:ATOH8(gene name)|psi-mi:ATOH8(display_short)|uniprotkb:ATH6(gene name synonym)|uniprotkb:BHLHA21(gene name synonym)|uniprotkb:Class A basic helix-loop-helix protein 21(gene name synonym)|uniprotkb:Helix-loop-helix protein hATH-6(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Chen et al. (2016) imex:IM-28461|pubmed:26496921 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0486"(UniProt) intact:EBI-26429642|imex:IM-28461-9 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-1759540(isoform-parent)|uniprotkb:P16298-4(isoform-parent)|ensembl:ENSG00000107758(gene)|ensembl:ENST00000394829(transcript) ensembl:ENSG00000168874(gene)|ensembl:ENST00000306279(transcript)|intact:EBI-3916470(isoform-parent) - - - figure legend:Fig. 5|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/10/27 2020/11/04 rogid:DW31UV3Jo673w3oSAX1K3u4KpUc9606 rogid:Zir7yvonqPNivKl57JF1k/RQPes9606 rigid:X9mnGEzVTXwpjYlRFh/IhGhoXcI false sufficient binding region:1-401 cyan fluorescent protein tag:c-c - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:Q99NA2 uniprotkb:P48453 intact:EBI-8333491|intact:MINT-4124565|uniprotkb:Q8C1I7|ensembl:ENSMUSP00000036981 intact:EBI-642618|uniprotkb:Q6NZR4|ensembl:ENSMUSP00000125722 psi-mi:atoh8_mouse(display_long)|uniprotkb:Atoh8(gene name)|psi-mi:Atoh8(display_short)|uniprotkb:Ath6(gene name synonym)|uniprotkb:Helix-loop-helix protein mATH-6(gene name synonym)|uniprotkb:Okadin(gene name synonym) psi-mi:pp2bb_mouse(display_long)|uniprotkb:Calmodulin-dependent calcineurin A subunit beta isoform(gene name synonym)|uniprotkb:CAM-PRP catalytic subunit(gene name synonym)|uniprotkb:Ppp3cb(gene name)|psi-mi:Ppp3cb(display_short)|uniprotkb:Calnb(gene name synonym) psi-mi:"MI:0416"(fluorescence microscopy) Chen et al. (2016) imex:IM-28461|pubmed:26496921 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0403"(colocalization) psi-mi:"MI:0486"(UniProt) intact:EBI-26441873|imex:IM-28461-12 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_722473.1|ensembl:ENSMUSG00000037621(gene)|ensembl:ENSMUST00000042646(transcript)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001704"(formation of primary germ layer)|go:"GO:0001937"(negative regulation of endothelial cell proliferation)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0008134"(transcription factor binding)|go:"GO:0010595"(positive regulation of endothelial cell migration)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0016607"(nuclear speck)|go:"GO:0030182"(neuron differentiation)|go:"GO:0035148"(tube formation)|go:"GO:0045603"(positive regulation of endothelial cell differentiation)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0046983"(protein dimerization activity)|go:"GO:0051450"(myoblast proliferation)|go:"GO:0060395"(SMAD protein signal transduction)|go:"GO:0070888"(E-box binding)|go:"GO:0140297"(DNA-binding transcription factor binding)|go:"GO:1902895"(positive regulation of miRNA transcription)|interpro:IPR011598(Helix-loop-helix DNA-binding)|interpro:IPR032660|interpro:IPR036638|mint:Q99NA2 refseq:NP_032940.1|refseq:NP_001297355.1|refseq:NP_001297356.1|ensembl:ENSMUSG00000021816(gene)|ensembl:ENSMUST00000159027(transcript)|go:"GO:0001915"(negative regulation of T cell mediated cytotoxicity)|go:"GO:0001946"(lymphangiogenesis)|go:"GO:0004722"(protein serine/threonine phosphatase activity)|go:"GO:0004723"(calcium-dependent protein serine/threonine phosphatase activity)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005955"(calcineurin complex)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0006470"(protein dephosphorylation)|go:"GO:0007507"(heart development)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0017156"(calcium-ion regulated exocytosis)|go:"GO:0019899"(enzyme binding)|go:"GO:0030018"(Z disc)|go:"GO:0030217"(T cell differentiation)|go:"GO:0030315"(T-tubule)|go:"GO:0030346"(protein phosphatase 2B binding)|go:"GO:0031987"(locomotion involved in locomotory behavior)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033173"(calcineurin-NFAT signaling cascade)|go:"GO:0033192"(calmodulin-dependent protein phosphatase activity)|go:"GO:0034097"(response to cytokine)|go:"GO:0035774"(positive regulation of insulin secretion involved in cellular response to glucose stimulus)|go:"GO:0043029"(T cell homeostasis)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045202"(synapse)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046983"(protein dimerization activity)|go:"GO:0050796"(regulation of insulin secretion)|go:"GO:0097720"(calcineurin-mediated signaling)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0106306"|go:"GO:0106307"|go:"GO:1900242"(regulation of synaptic vesicle endocytosis)|interpro:IPR004843(Metallophosphoesterase)|interpro:IPR006186("Serine/threonine-specific protein phosphatase and bis(5-nucleosyl)-tetraphosphatase")|interpro:IPR029052|interpro:IPR041751|interpro:IPR043360|mint:P48453|reactome:R-MMU-2025928|reactome:R-MMU-2871809|reactome:R-MMU-4086398|reactome:R-MMU-5607763|go:"GO:0005516"(calmodulin binding) go:"GO:0005737"(cytoplasm) comment:mint - figure legend:Fig. 2E-H|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:10090(mouse-c2c12)|taxid:10090(Mouse C3H muscle myoblast) - 2020/10/27 2020/11/03 rogid:uc3SIrcUmRN2R2iZ7TvgSXhkUXM10090 rogid:YD7q3dcL87htgwHRd5m5ReMlqd010090 rigid:oT6HB7sShQlVHB5E3/mVf6jMSqY false - - - - psi-mi:"MI:1200"(immunocytochemistry) psi-mi:"MI:1200"(immunocytochemistry)