#ID(s) interactor A	ID(s) interactor B	Alt. ID(s) interactor A	Alt. ID(s) interactor B	Alias(es) interactor A	Alias(es) interactor B	Interaction detection method(s)	Publication 1st author(s)	Publication Identifier(s)	Taxid interactor A	Taxid interactor B	Interaction type(s)	Source database(s)	Interaction identifier(s)	Confidence value(s)	Expansion method(s)	Biological role(s) interactor A	Biological role(s) interactor B	Experimental role(s) interactor A	Experimental role(s) interactor B	Type(s) interactor A	Type(s) interactor B	Xref(s) interactor A	Xref(s) interactor B	Interaction Xref(s)	Annotation(s) interactor A	Annotation(s) interactor B	Interaction annotation(s)	Host organism(s)	Interaction parameter(s)	Creation date	Update date	Checksum(s) interactor A	Checksum(s) interactor B	Interaction Checksum(s)	Negative	Feature(s) interactor A	Feature(s) interactor B	Stoichiometry(s) interactor A	Stoichiometry(s) interactor B	Identification method participant A	Identification method participant B
uniprotkb:Q61026	uniprotkb:P04150-1	intact:EBI-688662|uniprotkb:E9QMH9|uniprotkb:O09001|uniprotkb:P97759|ensembl:ENSMUSP00000006037	intact:EBI-15750116|ensembl:ENSP00000343205|ensembl:ENSP00000377977|ensembl:ENSP00000427672	psi-mi:ncoa2_mouse(display_long)|uniprotkb:Transcriptional intermediary factor 2(gene name synonym)|uniprotkb:Glucocorticoid receptor-interacting protein 1(gene name synonym)|uniprotkb:Ncoa2(gene name)|psi-mi:Ncoa2(display_short)|uniprotkb:Grip1(gene name synonym)|uniprotkb:Tif2(gene name synonym)|uniprotkb:Src2(gene name synonym)|uniprotkb:Steroid receptor coactivator 2(gene name synonym)	psi-mi:p04150-1(display_long)|uniprotkb:NR3C1(gene name)|psi-mi:NR3C1(display_short)|uniprotkb:GRL(gene name synonym)|uniprotkb:Nuclear receptor subfamily 3 group C member 1(gene name synonym)|uniprotkb:Alpha-A(isoform synonym)|uniprotkb:GR-alphaA(isoform synonym)	psi-mi:"MI:0096"(pull down)	Nicolaides et al. (2015)	pubmed:26031419|imex:IM-27730	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-25431806|imex:IM-27730-1	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_032704.2|refseq:XP_006495528.1|dip:DIP-5979N|ensembl:ENSMUSG00000005886(gene)|ensembl:ENSMUST00000006037(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0001162"(RNA polymerase II intronic transcription regulatory region sequence-specific DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005791"(rough endoplasmic reticulum)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005874"(microtubule)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0007623"(circadian rhythm)|go:"GO:0008134"(transcription factor binding)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0010906"(regulation of glucose metabolic process)|go:"GO:0014069"(postsynaptic density)|go:"GO:0016604"(nuclear body)|go:"GO:0016922"(nuclear receptor binding)|go:"GO:0017162"(aryl hydrocarbon receptor binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030165"(PDZ domain binding)|go:"GO:0030331"(estrogen receptor binding)|go:"GO:0030374"(nuclear receptor coactivator activity)|go:"GO:0030425"(dendrite)|go:"GO:0032570"(response to progesterone)|go:"GO:0032870"(cellular response to hormone stimulus)|go:"GO:0032922"(circadian regulation of gene expression)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033142"(progesterone receptor binding)|go:"GO:0035259"(glucocorticoid receptor binding)|go:"GO:0042974"(retinoic acid receptor binding)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043197"(dendritic spine)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045475"(locomotor rhythm)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045925"(positive regulation of female receptivity)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046965"(retinoid X receptor binding)|go:"GO:0046966"(thyroid hormone receptor binding)|go:"GO:0046983"(protein dimerization activity)|go:"GO:0048786"(presynaptic active zone)|go:"GO:0070182"(DNA polymerase binding)|go:"GO:1904017"(cellular response to Thyroglobulin triiodothyronine)|go:"GO:2000324"(positive regulation of glucocorticoid receptor signaling pathway)|interpro:IPR000014(PAS)|interpro:IPR009110(Nuclear receptor coactivator, interlocking)|interpro:IPR010011(Protein of unknown function DUF1518)|interpro:IPR011598(Helix-loop-helix DNA-binding)|interpro:IPR013767(PAS fold)|interpro:IPR014920(Nuclear receptor coactivator, Ncoa-type, interlocking)|interpro:IPR014935(Steroid receptor coactivator)|interpro:IPR017426(Nuclear receptor coactivator)|interpro:IPR028822|interpro:IPR032565|interpro:IPR035965|interpro:IPR036638|interpro:IPR037077|mint:Q61026|rcsb pdb:1L2I|rcsb pdb:1OSV|rcsb pdb:1WM0|rcsb pdb:2Q6J|rcsb pdb:2QA6|rcsb pdb:2QA8|rcsb pdb:2QAB|rcsb pdb:2QGT|rcsb pdb:2QGW|rcsb pdb:2QH6|rcsb pdb:2QPY|rcsb pdb:2QR9|rcsb pdb:2QSE|rcsb pdb:2QXM|rcsb pdb:2QZO|rcsb pdb:3MNE|rcsb pdb:3MNO|rcsb pdb:3MNP|reactome:R-MMU-159418|reactome:R-MMU-192105|reactome:R-MMU-193368|reactome:R-MMU-193807|reactome:R-MMU-211976|reactome:R-MMU-3214847|reactome:R-MMU-400206|reactome:R-MMU-5625886|reactome:R-MMU-9018519|reactome:R-MMU-9707564	ensembl:ENSG00000113580(gene)|ensembl:ENST00000343796(transcript)|ensembl:ENST00000394464(transcript)|ensembl:ENST00000503201(transcript)|intact:EBI-493507(isoform-parent)	-	-	isoform-comment:Predominant physiological form.	figure legend:Fig. 5|comment:"Presence of dexamethasone (CHEBI:41879) had no effect on mutant binding"|dataset:Rare diseases - Interactions investigated in the context of Rare genetic disease|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2020/02/20	2020/02/20	rogid:NiMKYc0EqYC+ubVPFVRai8H/cNk10090	rogid:4IOUe8VfG++O0M9uS6phAd8TBzw9606	rigid:BCruf5WB5ZbWoMkAOLqEjcDSrg8	false	glutathione s tranferase tag:n-n|sufficient binding region:740-1217	mutation with no effect:726-726	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:P04150-1	uniprotkb:Q61026	intact:EBI-15750116|ensembl:ENSP00000343205|ensembl:ENSP00000377977|ensembl:ENSP00000427672	intact:EBI-688662|uniprotkb:E9QMH9|uniprotkb:O09001|uniprotkb:P97759|ensembl:ENSMUSP00000006037	psi-mi:p04150-1(display_long)|uniprotkb:NR3C1(gene name)|psi-mi:NR3C1(display_short)|uniprotkb:GRL(gene name synonym)|uniprotkb:Nuclear receptor subfamily 3 group C member 1(gene name synonym)|uniprotkb:Alpha-A(isoform synonym)|uniprotkb:GR-alphaA(isoform synonym)	psi-mi:ncoa2_mouse(display_long)|uniprotkb:Transcriptional intermediary factor 2(gene name synonym)|uniprotkb:Glucocorticoid receptor-interacting protein 1(gene name synonym)|uniprotkb:Ncoa2(gene name)|psi-mi:Ncoa2(display_short)|uniprotkb:Grip1(gene name synonym)|uniprotkb:Tif2(gene name synonym)|uniprotkb:Src2(gene name synonym)|uniprotkb:Steroid receptor coactivator 2(gene name synonym)	psi-mi:"MI:0096"(pull down)	Nicolaides et al. (2015)	pubmed:26031419|imex:IM-27730	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-25440876|imex:IM-27730-2	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000113580(gene)|ensembl:ENST00000343796(transcript)|ensembl:ENST00000394464(transcript)|ensembl:ENST00000503201(transcript)|intact:EBI-493507(isoform-parent)	refseq:NP_032704.2|refseq:XP_006495528.1|dip:DIP-5979N|ensembl:ENSMUSG00000005886(gene)|ensembl:ENSMUST00000006037(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0001162"(RNA polymerase II intronic transcription regulatory region sequence-specific DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005791"(rough endoplasmic reticulum)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005874"(microtubule)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0007623"(circadian rhythm)|go:"GO:0008134"(transcription factor binding)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0010906"(regulation of glucose metabolic process)|go:"GO:0014069"(postsynaptic density)|go:"GO:0016604"(nuclear body)|go:"GO:0016922"(nuclear receptor binding)|go:"GO:0017162"(aryl hydrocarbon receptor binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030165"(PDZ domain binding)|go:"GO:0030331"(estrogen receptor binding)|go:"GO:0030374"(nuclear receptor coactivator activity)|go:"GO:0030425"(dendrite)|go:"GO:0032570"(response to progesterone)|go:"GO:0032870"(cellular response to hormone stimulus)|go:"GO:0032922"(circadian regulation of gene expression)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033142"(progesterone receptor binding)|go:"GO:0035259"(glucocorticoid receptor binding)|go:"GO:0042974"(retinoic acid receptor binding)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043197"(dendritic spine)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045475"(locomotor rhythm)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045925"(positive regulation of female receptivity)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046965"(retinoid X receptor binding)|go:"GO:0046966"(thyroid hormone receptor binding)|go:"GO:0046983"(protein dimerization activity)|go:"GO:0048786"(presynaptic active zone)|go:"GO:0070182"(DNA polymerase binding)|go:"GO:1904017"(cellular response to Thyroglobulin triiodothyronine)|go:"GO:2000324"(positive regulation of glucocorticoid receptor signaling pathway)|interpro:IPR000014(PAS)|interpro:IPR009110(Nuclear receptor coactivator, interlocking)|interpro:IPR010011(Protein of unknown function DUF1518)|interpro:IPR011598(Helix-loop-helix DNA-binding)|interpro:IPR013767(PAS fold)|interpro:IPR014920(Nuclear receptor coactivator, Ncoa-type, interlocking)|interpro:IPR014935(Steroid receptor coactivator)|interpro:IPR017426(Nuclear receptor coactivator)|interpro:IPR028822|interpro:IPR032565|interpro:IPR035965|interpro:IPR036638|interpro:IPR037077|mint:Q61026|rcsb pdb:1L2I|rcsb pdb:1OSV|rcsb pdb:1WM0|rcsb pdb:2Q6J|rcsb pdb:2QA6|rcsb pdb:2QA8|rcsb pdb:2QAB|rcsb pdb:2QGT|rcsb pdb:2QGW|rcsb pdb:2QH6|rcsb pdb:2QPY|rcsb pdb:2QR9|rcsb pdb:2QSE|rcsb pdb:2QXM|rcsb pdb:2QZO|rcsb pdb:3MNE|rcsb pdb:3MNO|rcsb pdb:3MNP|reactome:R-MMU-159418|reactome:R-MMU-192105|reactome:R-MMU-193368|reactome:R-MMU-193807|reactome:R-MMU-211976|reactome:R-MMU-3214847|reactome:R-MMU-400206|reactome:R-MMU-5625886|reactome:R-MMU-9018519|reactome:R-MMU-9707564	-	isoform-comment:Predominant physiological form.	-	figure legend:Fig. 5|dataset:Rare diseases - Interactions investigated in the context of Rare genetic disease|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2020/02/20	2020/03/02	rogid:4IOUe8VfG++O0M9uS6phAd8TBzw9606	rogid:NiMKYc0EqYC+ubVPFVRai8H/cNk10090	rigid:BCruf5WB5ZbWoMkAOLqEjcDSrg8	false	mutation decreasing interaction strength:726-726	glutathione s tranferase tag:n-n|sufficient binding region:559-774	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:Q61026	uniprotkb:P04150-1	intact:EBI-688662|uniprotkb:E9QMH9|uniprotkb:O09001|uniprotkb:P97759|ensembl:ENSMUSP00000006037	intact:EBI-15750116|ensembl:ENSP00000343205|ensembl:ENSP00000377977|ensembl:ENSP00000427672	psi-mi:ncoa2_mouse(display_long)|uniprotkb:Transcriptional intermediary factor 2(gene name synonym)|uniprotkb:Glucocorticoid receptor-interacting protein 1(gene name synonym)|uniprotkb:Ncoa2(gene name)|psi-mi:Ncoa2(display_short)|uniprotkb:Grip1(gene name synonym)|uniprotkb:Tif2(gene name synonym)|uniprotkb:Src2(gene name synonym)|uniprotkb:Steroid receptor coactivator 2(gene name synonym)	psi-mi:p04150-1(display_long)|uniprotkb:NR3C1(gene name)|psi-mi:NR3C1(display_short)|uniprotkb:GRL(gene name synonym)|uniprotkb:Nuclear receptor subfamily 3 group C member 1(gene name synonym)|uniprotkb:Alpha-A(isoform synonym)|uniprotkb:GR-alphaA(isoform synonym)	psi-mi:"MI:0096"(pull down)	Nicolaides et al. (2015)	pubmed:26031419|imex:IM-27730	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-25441289|imex:IM-27730-4	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_032704.2|refseq:XP_006495528.1|dip:DIP-5979N|ensembl:ENSMUSG00000005886(gene)|ensembl:ENSMUST00000006037(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0001162"(RNA polymerase II intronic transcription regulatory region sequence-specific DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005791"(rough endoplasmic reticulum)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005874"(microtubule)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0007623"(circadian rhythm)|go:"GO:0008134"(transcription factor binding)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0010906"(regulation of glucose metabolic process)|go:"GO:0014069"(postsynaptic density)|go:"GO:0016604"(nuclear body)|go:"GO:0016922"(nuclear receptor binding)|go:"GO:0017162"(aryl hydrocarbon receptor binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030165"(PDZ domain binding)|go:"GO:0030331"(estrogen receptor binding)|go:"GO:0030374"(nuclear receptor coactivator activity)|go:"GO:0030425"(dendrite)|go:"GO:0032570"(response to progesterone)|go:"GO:0032870"(cellular response to hormone stimulus)|go:"GO:0032922"(circadian regulation of gene expression)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033142"(progesterone receptor binding)|go:"GO:0035259"(glucocorticoid receptor binding)|go:"GO:0042974"(retinoic acid receptor binding)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043197"(dendritic spine)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045475"(locomotor rhythm)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045925"(positive regulation of female receptivity)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046965"(retinoid X receptor binding)|go:"GO:0046966"(thyroid hormone receptor binding)|go:"GO:0046983"(protein dimerization activity)|go:"GO:0048786"(presynaptic active zone)|go:"GO:0070182"(DNA polymerase binding)|go:"GO:1904017"(cellular response to Thyroglobulin triiodothyronine)|go:"GO:2000324"(positive regulation of glucocorticoid receptor signaling pathway)|interpro:IPR000014(PAS)|interpro:IPR009110(Nuclear receptor coactivator, interlocking)|interpro:IPR010011(Protein of unknown function DUF1518)|interpro:IPR011598(Helix-loop-helix DNA-binding)|interpro:IPR013767(PAS fold)|interpro:IPR014920(Nuclear receptor coactivator, Ncoa-type, interlocking)|interpro:IPR014935(Steroid receptor coactivator)|interpro:IPR017426(Nuclear receptor coactivator)|interpro:IPR028822|interpro:IPR032565|interpro:IPR035965|interpro:IPR036638|interpro:IPR037077|mint:Q61026|rcsb pdb:1L2I|rcsb pdb:1OSV|rcsb pdb:1WM0|rcsb pdb:2Q6J|rcsb pdb:2QA6|rcsb pdb:2QA8|rcsb pdb:2QAB|rcsb pdb:2QGT|rcsb pdb:2QGW|rcsb pdb:2QH6|rcsb pdb:2QPY|rcsb pdb:2QR9|rcsb pdb:2QSE|rcsb pdb:2QXM|rcsb pdb:2QZO|rcsb pdb:3MNE|rcsb pdb:3MNO|rcsb pdb:3MNP|reactome:R-MMU-159418|reactome:R-MMU-192105|reactome:R-MMU-193368|reactome:R-MMU-193807|reactome:R-MMU-211976|reactome:R-MMU-3214847|reactome:R-MMU-400206|reactome:R-MMU-5625886|reactome:R-MMU-9018519|reactome:R-MMU-9707564	ensembl:ENSG00000113580(gene)|ensembl:ENST00000343796(transcript)|ensembl:ENST00000394464(transcript)|ensembl:ENST00000503201(transcript)|intact:EBI-493507(isoform-parent)	-	-	isoform-comment:Predominant physiological form.	figure legend:Fig. 5|dataset:Rare diseases - Interactions investigated in the context of Rare genetic disease|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2020/02/20	2020/03/02	rogid:NiMKYc0EqYC+ubVPFVRai8H/cNk10090	rogid:4IOUe8VfG++O0M9uS6phAd8TBzw9606	rigid:BCruf5WB5ZbWoMkAOLqEjcDSrg8	false	glutathione s tranferase tag:n-n|sufficient binding region:559-774	mutation with no effect:726-726	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)