#ID(s) interactor A ID(s) interactor B Alt. ID(s) interactor A Alt. ID(s) interactor B Alias(es) interactor A Alias(es) interactor B Interaction detection method(s) Publication 1st author(s) Publication Identifier(s) Taxid interactor A Taxid interactor B Interaction type(s) Source database(s) Interaction identifier(s) Confidence value(s) Expansion method(s) Biological role(s) interactor A Biological role(s) interactor B Experimental role(s) interactor A Experimental role(s) interactor B Type(s) interactor A Type(s) interactor B Xref(s) interactor A Xref(s) interactor B Interaction Xref(s) Annotation(s) interactor A Annotation(s) interactor B Interaction annotation(s) Host organism(s) Interaction parameter(s) Creation date Update date Checksum(s) interactor A Checksum(s) interactor B Interaction Checksum(s) Negative Feature(s) interactor A Feature(s) interactor B Stoichiometry(s) interactor A Stoichiometry(s) interactor B Identification method participant A Identification method participant B uniprotkb:Q9JJC6 uniprotkb:P0C6X9-PRO_0000037352 intact:EBI-8320724|uniprotkb:Q80WV8|intact:MINT-4129976|ensembl:ENSMUSP00000050014 intact:EBI-25507607 psi-mi:ripl1_mouse(display_long)|uniprotkb:MNCb-2440(orf name)|uniprotkb:Rilpl1(gene name)|psi-mi:Rilpl1(display_short)|uniprotkb:Rab-interacting lysosomal-like protein 1(gene name synonym) psi-mi:p0c6x9-pro_0000037352(display_long)|uniprotkb:rep(gene name)|psi-mi:rep(display_short)|uniprotkb:ORF1ab polyprotein(gene name synonym)|uniprotkb:1a-1b(orf name) psi-mi:"MI:0398"(two hybrid pooling approach) Vidalain et al. (2014) imex:IM-27904|pubmed:25720483 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:11142(cvma5)|taxid:11142("Murine coronavirus (strain A59)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-25508183|imex:IM-27904-1 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_067405.1|ensembl:ENSMUSG00000029392(gene)|ensembl:ENSMUST00000062153(transcript)|go:"GO:0003382"(epithelial cell morphogenesis)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005814"(centriole)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005929"(cilium)|go:"GO:0036064"(ciliary basal body)|go:"GO:0046983"(protein dimerization activity)|go:"GO:0060271"(cilium assembly)|go:"GO:1901214"(regulation of neuron death)|go:"GO:1903445"(protein transport from ciliary membrane to plasma membrane)|interpro:IPR019143|interpro:IPR021563|interpro:IPR034743|interpro:IPR034744|mint:Q9JJC6 intact:EBI-25507525(chain-parent) - comment:mint|function:Does not regulate lysosomal morphology and distribution chain-seq-start:6878|chain-seq-end:7176 figure legend:T1|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) - 2020/04/09 2020/04/10 rogid:61WiGzawdgig/og5CxZhZImRvAs10090 rogid:pXQrOqyRniN68m+DFeXl32r3OPU11142 rigid:ACKiKHCBmGoNEVIskcBRlFzYkT4 false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q68EF0 uniprotkb:P0C6X9-PRO_0000037352 intact:EBI-16730154|ensembl:ENSMUSP00000020375 intact:EBI-25507607 psi-mi:rab3i_mouse(display_long)|uniprotkb:Rabin-3(gene name synonym)|uniprotkb:SSX2-interacting protein(gene name synonym)|uniprotkb:Rab3ip(gene name)|psi-mi:Rab3ip(display_short)|uniprotkb:Rabin8(gene name synonym) psi-mi:p0c6x9-pro_0000037352(display_long)|uniprotkb:rep(gene name)|psi-mi:rep(display_short)|uniprotkb:ORF1ab polyprotein(gene name synonym)|uniprotkb:1a-1b(orf name) psi-mi:"MI:0398"(two hybrid pooling approach) Vidalain et al. (2014) imex:IM-27904|pubmed:25720483 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:11142(cvma5)|taxid:11142("Murine coronavirus (strain A59)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-25508294|imex:IM-27904-61 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000064181(gene)|ensembl:ENSMUST00000020375(transcript)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0006612"(protein targeting to membrane)|go:"GO:0006887"(exocytosis)|go:"GO:0030027"(lamellipodium)|go:"GO:0033365"(protein localization to organelle)|go:"GO:0042802"(identical protein binding)|go:"GO:0051490"(negative regulation of filopodium assembly)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051020"(GTPase binding)|go:"GO:0060271"(cilium assembly)|go:"GO:1990635"(proximal dendrite)|interpro:IPR040351|mint:Q68EF0|reactome:R-MMU-5620912|reactome:R-MMU-5620916|reactome:R-MMU-5620922|reactome:R-MMU-8876198|go:"GO:0070319"(Golgi to plasma membrane transport vesicle)|refseq:NP_001003950.1 intact:EBI-25507525(chain-parent) - - chain-seq-start:6878|chain-seq-end:7176 figure legend:T1|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) - 2020/04/09 2020/04/11 rogid:vJqpNpn2gSYd/89uDKCBOO/KQDs10090 rogid:pXQrOqyRniN68m+DFeXl32r3OPU11142 rigid:Tm+VRNnG8SVaAS6SSAo+rG/E9XQ false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q8BHK0 uniprotkb:P0C6X9-PRO_0000037352 intact:EBI-25508298|ensembl:ENSMUSP00000086646|ensembl:ENSMUSP00000112629 intact:EBI-25507607 psi-mi:pnma2_mouse(display_long)|uniprotkb:Pnma2(gene name)|psi-mi:Pnma2(display_short) psi-mi:p0c6x9-pro_0000037352(display_long)|uniprotkb:rep(gene name)|psi-mi:rep(display_short)|uniprotkb:ORF1ab polyprotein(gene name synonym)|uniprotkb:1a-1b(orf name) psi-mi:"MI:0398"(two hybrid pooling approach) Vidalain et al. (2014) imex:IM-27904|pubmed:25720483 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:11142(cvma5)|taxid:11142("Murine coronavirus (strain A59)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-25508313|imex:IM-27904-63 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000046204(gene)|ensembl:ENSMUST00000089236(transcript)|ensembl:ENSMUST00000122431(transcript)|go:"GO:0005730"(nucleolus)|interpro:IPR026523|interpro:IPR026525|mint:Q8BHK0|refseq:NP_780707.1|refseq:XP_006519052.1|refseq:XP_006519053.1 intact:EBI-25507525(chain-parent) - - chain-seq-start:6878|chain-seq-end:7176 figure legend:T1|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) - 2020/04/09 2020/04/11 rogid:pyDhbVEiWxqo80VR0iHQLLpWm8A10090 rogid:pXQrOqyRniN68m+DFeXl32r3OPU11142 rigid:pbrl8jaOqVPmxKTuMkYuPeOLPwI false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:P97434 uniprotkb:P0C6X9-PRO_0000037352 intact:EBI-2365654|uniprotkb:Q3TBR5|uniprotkb:Q3TC85|uniprotkb:Q3TRS0|uniprotkb:Q3U1Y8|uniprotkb:Q3U3E4|uniprotkb:Q5SWZ3|uniprotkb:Q5SWZ4|uniprotkb:Q5SWZ7|uniprotkb:Q6P559|uniprotkb:Q80YC8|ensembl:ENSMUSP00000112072 intact:EBI-25507607 psi-mi:mprip_mouse(display_long)|uniprotkb:Mprip(gene name)|psi-mi:Mprip(display_short)|uniprotkb:Kiaa0864(gene name synonym)|uniprotkb:Mrip(gene name synonym)|uniprotkb:Rhoip3(gene name synonym)|uniprotkb:Rho-interacting protein 3(gene name synonym)|uniprotkb:p116Rip(gene name synonym) psi-mi:p0c6x9-pro_0000037352(display_long)|uniprotkb:rep(gene name)|psi-mi:rep(display_short)|uniprotkb:ORF1ab polyprotein(gene name synonym)|uniprotkb:1a-1b(orf name) psi-mi:"MI:0398"(two hybrid pooling approach) Vidalain et al. (2014) imex:IM-27904|pubmed:25720483 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:11142(cvma5)|taxid:11142("Murine coronavirus (strain A59)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-25508317|imex:IM-27904-65 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_036157.2|refseq:NP_957697.1|refseq:XP_006533503.1|ensembl:ENSMUSG00000005417(gene)|ensembl:ENSMUST00000116371(transcript)|go:"GO:0001725"(stress fiber)|go:"GO:0001934"(positive regulation of protein phosphorylation)|go:"GO:0005829"(cytosol)|go:"GO:0007015"(actin filament organization)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0032507"(maintenance of protein location in cell)|go:"GO:0035509"(negative regulation of myosin-light-chain-phosphatase activity)|go:"GO:0051015"(actin filament binding)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR039597|mint:P97434 intact:EBI-25507525(chain-parent) - - chain-seq-start:6878|chain-seq-end:7176 figure legend:T1|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) - 2020/04/09 2020/04/11 rogid:jwOKcVLEosfXdMVQ5LfEjkan/U410090 rogid:pXQrOqyRniN68m+DFeXl32r3OPU11142 rigid:t13FQCOAzth3LACOu504M2jtUgk false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:A2A870 uniprotkb:P0C6X9-PRO_0000037352 intact:EBI-11567461|uniprotkb:Q8BSP0|uniprotkb:A2A871|uniprotkb:Q99MZ9|uniprotkb:B2RQ77|ensembl:ENSMUSP00000099320|ensembl:ENSMUSP00000102043 intact:EBI-25507607 psi-mi:fbf1_mouse(display_long)|uniprotkb:Fbf1(gene name)|psi-mi:Fbf1(display_short) psi-mi:p0c6x9-pro_0000037352(display_long)|uniprotkb:rep(gene name)|psi-mi:rep(display_short)|uniprotkb:ORF1ab polyprotein(gene name synonym)|uniprotkb:1a-1b(orf name) psi-mi:"MI:0398"(two hybrid pooling approach) Vidalain et al. (2014) imex:IM-27904|pubmed:25720483 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:11142(cvma5)|taxid:11142("Murine coronavirus (strain A59)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-25508321|imex:IM-27904-3 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_766159.3|refseq:XP_006533155.1|refseq:XP_006533156.1|refseq:XP_006533157.1|refseq:XP_011247250.1|ensembl:ENSMUSG00000020776(gene)|ensembl:ENSMUST00000103031(transcript)|ensembl:ENSMUST00000106435(transcript)|go:"GO:0000922"(spindle pole)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005814"(centriole)|go:"GO:0036064"(ciliary basal body)|go:"GO:0043296"(apical junction complex)|go:"GO:0043297"(apical junction assembly)|go:"GO:0045095"(keratin filament)|go:"GO:0060271"(cilium assembly)|go:"GO:0097539"(ciliary transition fiber)|interpro:IPR033561|mint:A2A870|reactome:R-MMU-5620912|go:"GO:0090162"(establishment of epithelial cell polarity) intact:EBI-25507525(chain-parent) - - chain-seq-start:6878|chain-seq-end:7176 figure legend:T1|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) - 2020/04/09 2020/04/11 rogid:lBosfua1LlObIvQDPUumR+8UTvQ10090 rogid:pXQrOqyRniN68m+DFeXl32r3OPU11142 rigid:qnNw++K7th4dPh988xpIk5ghBcc false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q5I043 uniprotkb:P0C6X9-PRO_0000037352 intact:EBI-16728724|ensembl:ENSMUSP00000047467|uniprotkb:Q6NZP3|uniprotkb:Q6ZPP1|uniprotkb:Q8BWI1 intact:EBI-25507607 psi-mi:ubp28_mouse(display_long)|uniprotkb:Deubiquitinating enzyme 28(gene name synonym)|uniprotkb:Ubiquitin thioesterase 28(gene name synonym)|uniprotkb:Ubiquitin-specific-processing protease 28(gene name synonym)|uniprotkb:Usp28(gene name)|psi-mi:Usp28(display_short)|uniprotkb:Kiaa1515(gene name synonym) psi-mi:p0c6x9-pro_0000037352(display_long)|uniprotkb:rep(gene name)|psi-mi:rep(display_short)|uniprotkb:ORF1ab polyprotein(gene name synonym)|uniprotkb:1a-1b(orf name) psi-mi:"MI:0398"(two hybrid pooling approach) Vidalain et al. (2014) imex:IM-27904|pubmed:25720483 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:11142(cvma5)|taxid:11142("Murine coronavirus (strain A59)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-25508325|imex:IM-27904-21 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000032267(gene)|ensembl:ENSMUST00000047349(transcript)|go:"GO:0000077"(DNA damage checkpoint signaling)|go:"GO:0004197"(cysteine-type endopeptidase activity)|go:"GO:0004843"(thiol-dependent deubiquitinase)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006281"(DNA repair)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0007265"(Ras protein signal transduction)|go:"GO:0008283"(cell population proliferation)|go:"GO:0010212"(response to ionizing radiation)|go:"GO:0016579"(protein deubiquitination)|go:"GO:0016604"(nuclear body)|go:"GO:0031647"(regulation of protein stability)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034644"(cellular response to UV)|go:"GO:0042771"(intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator)|interpro:IPR001394(Peptidase C19, ubiquitin carboxyl-terminal hydrolase 2)|interpro:IPR009060(UBA-like)|interpro:IPR018200|interpro:IPR028889|interpro:IPR038765|mint:Q5I043|reactome:R-MMU-5689880|refseq:NP_780691.2 intact:EBI-25507525(chain-parent) - - chain-seq-start:6878|chain-seq-end:7176 figure legend:T1|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) - 2020/04/09 2020/04/11 rogid:BzdWmsJwWpIcQAPcUj9x+ZEYE0s10090 rogid:pXQrOqyRniN68m+DFeXl32r3OPU11142 rigid:4dhOAuJ4TOjw3ROOem1f7KZAL6w false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q8BHN3 uniprotkb:P0C6X9-PRO_0000037351 intact:EBI-2013099|uniprotkb:O08794|uniprotkb:Q80U81|uniprotkb:Q9CS53|uniprotkb:Q149A6|ensembl:ENSMUSP00000158122 intact:EBI-25508329 psi-mi:ganab_mouse(display_long)|uniprotkb:Ganab(gene name)|psi-mi:Ganab(display_short)|uniprotkb:G2an(gene name synonym)|uniprotkb:Kiaa0088(gene name synonym)|uniprotkb:Glucosidase II subunit alpha(gene name synonym)|uniprotkb:Alpha-glucosidase 2(gene name synonym) psi-mi:p0c6x9-pro_0000037351(display_long)|uniprotkb:rep(gene name)|psi-mi:rep(display_short)|uniprotkb:ORF1ab polyprotein(gene name synonym)|uniprotkb:1a-1b(orf name) psi-mi:"MI:0398"(two hybrid pooling approach) Vidalain et al. (2014) imex:IM-27904|pubmed:25720483 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:11142(cvma5)|taxid:11142("Murine coronavirus (strain A59)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-25508335|imex:IM-27904-5 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_032086.1|refseq:NP_001280550.1|ensembl:ENSMUSG00000071650(gene)|ensembl:ENSMUST00000235274(transcript)|go:"GO:0004553"(hydrolase activity, hydrolyzing O-glycosyl compounds)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005975"(carbohydrate metabolic process)|go:"GO:0006491"(N-glycan processing)|go:"GO:0015926"(glucosidase activity)|go:"GO:0017177"(glucosidase II complex)|go:"GO:0030246"(carbohydrate binding)|go:"GO:0033919"(glucan 1,3-alpha-glucosidase activity)|go:"GO:0042470"(melanosome)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0090599"(alpha-glucosidase activity)|interpro:IPR000322(Glycoside hydrolase, family 31)|interpro:IPR011013(Glycoside hydrolase-type carbohydrate-binding)|interpro:IPR013780(Glycosyl hydrolase, family 13, all-beta)|interpro:IPR017853(Glycoside hydrolase, catalytic core)|interpro:IPR025887|interpro:IPR030458|interpro:IPR030459|mint:Q8BHN3|rcsb pdb:5F0E|rcsb pdb:5H9O|rcsb pdb:5HJO|rcsb pdb:5HJR|rcsb pdb:5IED|rcsb pdb:5IEE|rcsb pdb:5IEF|rcsb pdb:5IEG intact:EBI-25507525(chain-parent) - - chain-seq-start:6504|chain-seq-end:6877 figure legend:T1|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) - 2020/04/09 2020/04/11 rogid:I4Pvx8YojD3dknu5o4krTM6vUH010090 rogid:NdD1xbWmlP5hWmr+MztL9FUqx1k11142 rigid:GkrOWdrpAjtHvUHgeg8uIIrPMTw false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:A2A870 uniprotkb:P0C6X9-PRO_0000037350 intact:EBI-11567461|uniprotkb:Q8BSP0|uniprotkb:A2A871|uniprotkb:Q99MZ9|uniprotkb:B2RQ77|ensembl:ENSMUSP00000099320|ensembl:ENSMUSP00000102043 intact:EBI-25508339 psi-mi:fbf1_mouse(display_long)|uniprotkb:Fbf1(gene name)|psi-mi:Fbf1(display_short) psi-mi:p0c6x9-pro_0000037350(display_long)|uniprotkb:rep(gene name)|psi-mi:rep(display_short)|uniprotkb:ORF1ab polyprotein(gene name synonym)|uniprotkb:1a-1b(orf name) psi-mi:"MI:0398"(two hybrid pooling approach) Vidalain et al. (2014) imex:IM-27904|pubmed:25720483 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:11142(cvma5)|taxid:11142("Murine coronavirus (strain A59)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-25508345|imex:IM-27904-67 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_766159.3|refseq:XP_006533155.1|refseq:XP_006533156.1|refseq:XP_006533157.1|refseq:XP_011247250.1|ensembl:ENSMUSG00000020776(gene)|ensembl:ENSMUST00000103031(transcript)|ensembl:ENSMUST00000106435(transcript)|go:"GO:0000922"(spindle pole)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005814"(centriole)|go:"GO:0036064"(ciliary basal body)|go:"GO:0043296"(apical junction complex)|go:"GO:0043297"(apical junction assembly)|go:"GO:0045095"(keratin filament)|go:"GO:0060271"(cilium assembly)|go:"GO:0097539"(ciliary transition fiber)|interpro:IPR033561|mint:A2A870|reactome:R-MMU-5620912|go:"GO:0090162"(establishment of epithelial cell polarity) intact:EBI-25507525(chain-parent) - - chain-seq-start:5983|chain-seq-end:6503 figure legend:T1|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) - 2020/04/09 2020/04/11 rogid:lBosfua1LlObIvQDPUumR+8UTvQ10090 rogid:3yTbgNOOBsNHRdvI81i3BU1eN3w11142 rigid:r5tynzA8oGQ8xkkuCUTsDrLhvic false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q99JP6 uniprotkb:P0C6X9-PRO_0000037350 intact:EBI-6272061|ensembl:ENSMUSP00000117033|uniprotkb:D3Z6N9|uniprotkb:Q9Z215 intact:EBI-25508339 psi-mi:home3_mouse(display_long)|uniprotkb:Homer3(gene name)|psi-mi:Homer3(display_short) psi-mi:p0c6x9-pro_0000037350(display_long)|uniprotkb:rep(gene name)|psi-mi:rep(display_short)|uniprotkb:ORF1ab polyprotein(gene name synonym)|uniprotkb:1a-1b(orf name) psi-mi:"MI:0398"(two hybrid pooling approach) Vidalain et al. (2014) imex:IM-27904|pubmed:25720483 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:11142(cvma5)|taxid:11142("Murine coronavirus (strain A59)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-25508349|imex:IM-27904-7 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000003573(gene)|ensembl:ENSMUST00000140212(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0007216"(G protein-coupled glutamate receptor signaling pathway)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0014069"(postsynaptic density)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030425"(dendrite)|go:"GO:0032703"(negative regulation of interleukin-2 production)|go:"GO:0035256"(G protein-coupled glutamate receptor binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0045178"(basal part of cell)|go:"GO:0070885"(negative regulation of calcineurin-NFAT signaling cascade)|go:"GO:0098962"(regulation of postsynaptic neurotransmitter receptor activity)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:2001256"(regulation of store-operated calcium entry)|interpro:IPR000697(EVH1)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR044100|mint:Q99JP6|reactome:R-MMU-6794361|refseq:NP_001139625.1|refseq:NP_036114.2 intact:EBI-25507525(chain-parent) - - chain-seq-start:5983|chain-seq-end:6503 figure legend:T1|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) - 2020/04/09 2020/04/11 rogid:7IOPI8VTi6aKK/I0tl4AiUUIXIU10090 rogid:3yTbgNOOBsNHRdvI81i3BU1eN3w11142 rigid:zUdz0xEa8TFbklSsK0xqd4eMcn8 false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:E9PW83 uniprotkb:P0C6X9-PRO_0000037350 intact:EBI-25508353|ensembl:ENSMUSP00000020003 intact:EBI-25508339 psi-mi:e9pw83_mouse(display_long)|uniprotkb:Fam184a(gene name)|psi-mi:Fam184a(display_short) psi-mi:p0c6x9-pro_0000037350(display_long)|uniprotkb:rep(gene name)|psi-mi:rep(display_short)|uniprotkb:ORF1ab polyprotein(gene name synonym)|uniprotkb:1a-1b(orf name) psi-mi:"MI:0398"(two hybrid pooling approach) Vidalain et al. (2014) imex:IM-27904|pubmed:25720483 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:11142(cvma5)|taxid:11142("Murine coronavirus (strain A59)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-25508365|imex:IM-27904-23 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000019856(gene)|ensembl:ENSMUST00000020003(transcript)|interpro:IPR029605|interpro:IPR029607|interpro:IPR039478|mint:E9PW83|refseq:NP_001074897.1 intact:EBI-25507525(chain-parent) - - chain-seq-start:5983|chain-seq-end:6503 figure legend:T1|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) - 2020/04/09 2020/04/11 rogid:kt1Ym3JhTqTi3VcYNgOJeO9S2fU10090 rogid:3yTbgNOOBsNHRdvI81i3BU1eN3w11142 rigid:jNAE2lWJTDnLYWYt6jPgdZ+uUXA false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q80YT7 uniprotkb:P0C6X9-PRO_0000037350 intact:EBI-16726361|uniprotkb:C4IXU1|uniprotkb:Q05CH5|uniprotkb:Q80U00|uniprotkb:Q8K240 intact:EBI-25508339 psi-mi:myome_mouse(display_long)|uniprotkb:Phosphodiesterase 4D-interacting protein(gene name synonym)|uniprotkb:Pde4dip(gene name)|psi-mi:Pde4dip(display_short)|uniprotkb:Kiaa0454(gene name synonym) psi-mi:p0c6x9-pro_0000037350(display_long)|uniprotkb:rep(gene name)|psi-mi:rep(display_short)|uniprotkb:ORF1ab polyprotein(gene name synonym)|uniprotkb:1a-1b(orf name) psi-mi:"MI:0398"(two hybrid pooling approach) Vidalain et al. (2014) imex:IM-27904|pubmed:25720483 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:11142(cvma5)|taxid:11142("Murine coronavirus (strain A59)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-25508369|imex:IM-27904-41 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005813"(centrosome)|go:"GO:0019899"(enzyme binding)|go:"GO:0030016"(myofibril)|go:"GO:0030953"(astral microtubule organization)|go:"GO:0034622"|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0090063"(positive regulation of microtubule nucleation)|go:"GO:1903358"(regulation of Golgi organization)|mint:Q80YT7|refseq:NP_001034465.2|refseq:NP_835181.2|interpro:IPR012943(Spindle associated)|interpro:IPR010630(Protein of unknown function DUF1220) intact:EBI-25507525(chain-parent) - - chain-seq-start:5983|chain-seq-end:6503 figure legend:T1|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) - 2020/04/09 2020/04/11 rogid:zVBkYyVR82H9Xm1vqn3lSkgZ//I10090 rogid:3yTbgNOOBsNHRdvI81i3BU1eN3w11142 rigid:ITek3GafH4zCn8oWT66EcNxbMYc false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q80TL7 uniprotkb:P0C6X9-PRO_0000037350 intact:EBI-25508373|ensembl:ENSMUSP00000073462|uniprotkb:Q3TRE3|uniprotkb:Q8BTA8|uniprotkb:Q8K4V3 intact:EBI-25508339 psi-mi:mon2_mouse(display_long)|uniprotkb:Mon2(gene name)|psi-mi:Mon2(display_short)|uniprotkb:Kiaa1040(gene name synonym)|uniprotkb:Sf21(gene name synonym)|uniprotkb:Protein SF21(gene name synonym) psi-mi:p0c6x9-pro_0000037350(display_long)|uniprotkb:rep(gene name)|psi-mi:rep(display_short)|uniprotkb:ORF1ab polyprotein(gene name synonym)|uniprotkb:1a-1b(orf name) psi-mi:"MI:0398"(two hybrid pooling approach) Vidalain et al. (2014) imex:IM-27904|pubmed:25720483 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:11142(cvma5)|taxid:11142("Murine coronavirus (strain A59)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-25508399|imex:IM-27904-43 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000034602(gene)|ensembl:ENSMUST00000073792(transcript)|go:"GO:0005829"(cytosol)|go:"GO:0006895"(Golgi to endosome transport)|go:"GO:0015031"(protein transport)|go:"GO:0031901"(early endosome membrane)|interpro:IPR015403(Protein of unknown function DUF1981, SEC7 associated)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR026829|interpro:IPR032629|interpro:IPR032691|interpro:IPR032817|mint:Q80TL7|refseq:NP_001156496.1|refseq:NP_700444.2 intact:EBI-25507525(chain-parent) - - chain-seq-start:5983|chain-seq-end:6503 figure legend:T1|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) - 2020/04/09 2020/04/11 rogid:TkAjsl4dNEWzHRzkPSzXfEf2K8M10090 rogid:3yTbgNOOBsNHRdvI81i3BU1eN3w11142 rigid:eCnuw5gBPvFpOKMuWdw4561mCPc false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q8BMD2 uniprotkb:P0C6X9-PRO_0000037350 intact:EBI-7089968|ensembl:ENSMUSP00000004055|ensembl:ENSMUSP00000039689|uniprotkb:Q9CRK5|intact:MINT-5190561|uniprotkb:Q4QQM0|uniprotkb:Q6ZQ10 intact:EBI-25508339 psi-mi:dzip1_mouse(display_long)|uniprotkb:DAZ-interacting protein 1 homolog(gene name synonym)|uniprotkb:Dzip1(gene name)|psi-mi:Dzip1(display_short)|uniprotkb:Kiaa0996(gene name synonym) psi-mi:p0c6x9-pro_0000037350(display_long)|uniprotkb:rep(gene name)|psi-mi:rep(display_short)|uniprotkb:ORF1ab polyprotein(gene name synonym)|uniprotkb:1a-1b(orf name) psi-mi:"MI:0398"(two hybrid pooling approach) Vidalain et al. (2014) imex:IM-27904|pubmed:25720483 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:11142(cvma5)|taxid:11142("Murine coronavirus (strain A59)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-25508403|imex:IM-27904-9 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:XP_011243448.1|refseq:XP_006519446.1|refseq:XP_006519447.1|refseq:XP_006519454.1|ensembl:ENSMUSG00000042156(gene)|ensembl:ENSMUST00000004055(transcript)|ensembl:ENSMUST00000047208(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005814"(centriole)|go:"GO:0005829"(cytosol)|go:"GO:0007224"(smoothened signaling pathway)|go:"GO:0007281"(germ cell development)|go:"GO:0007283"(spermatogenesis)|go:"GO:0033365"(protein localization to organelle)|go:"GO:0034451"(centriolar satellite)|go:"GO:0036064"(ciliary basal body)|go:"GO:0043393"(regulation of protein binding)|go:"GO:0044782"(cilium organization)|go:"GO:0045184"(establishment of protein localization)|go:"GO:0045724"(positive regulation of cilium assembly)|go:"GO:0046872"(metal ion binding)|go:"GO:0051220"(cytoplasmic sequestering of protein)|go:"GO:0060271"(cilium assembly)|go:"GO:0061512"(protein localization to cilium)|go:"GO:0097539"(ciliary transition fiber)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR032714|mint:Q8BMD2|reactome:R-MMU-5632684|refseq:XP_017171615.1|refseq:NP_080219.2|dip:DIP-61407N intact:EBI-25507525(chain-parent) - comment:mint|function:May participate in spermatogenesis via its interaction with DAZ chain-seq-start:5983|chain-seq-end:6503 figure legend:T1|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) - 2020/04/09 2020/04/11 rogid:NA269zIRdCLFDHI5h6MX8MUvZwM10090 rogid:3yTbgNOOBsNHRdvI81i3BU1eN3w11142 rigid:+39FmovQvRTCQ4fawFXTzxdd5Vo false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q7TNM2 uniprotkb:P0C6X9-PRO_0000037350 intact:EBI-912167|uniprotkb:Q60717|uniprotkb:Q6P1I9|ensembl:ENSMUSP00000036053 intact:EBI-25508339 psi-mi:tri46_mouse(display_long)|uniprotkb:Trim46(gene name)|psi-mi:Trim46(display_short)|uniprotkb:Trific(gene name synonym)|uniprotkb:Tripartite, fibronectin type-III and C-terminal SPRY motif protein(gene name synonym)|uniprotkb:Gene Y protein(gene name synonym) psi-mi:p0c6x9-pro_0000037350(display_long)|uniprotkb:rep(gene name)|psi-mi:rep(display_short)|uniprotkb:ORF1ab polyprotein(gene name synonym)|uniprotkb:1a-1b(orf name) psi-mi:"MI:0398"(two hybrid pooling approach) Vidalain et al. (2014) imex:IM-27904|pubmed:25720483 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:11142(cvma5)|taxid:11142("Murine coronavirus (strain A59)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-25508407|imex:IM-27904-69 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_898858.1|ensembl:ENSMUSG00000042766(gene)|ensembl:ENSMUST00000041022(transcript)|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0001578"(microtubule bundle formation)|go:"GO:0001764"(neuron migration)|go:"GO:0007409"(axonogenesis)|go:"GO:0008017"(microtubule binding)|go:"GO:0008270"(zinc ion binding)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0030517"(negative regulation of axon extension)|go:"GO:0043194"(axon initial segment)|go:"GO:0044304"(main axon)|go:"GO:0048490"(anterograde synaptic vesicle transport)|go:"GO:0099612"(protein localization to axon)|go:"GO:1901953"(positive regulation of anterograde dense core granule transport)|go:"GO:1903827"|go:"GO:1904115"(axon cytoplasm)|go:"GO:1990769"(proximal neuron projection)|interpro:IPR000315(Zinc finger, B-box)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR001870("B302 (SPRY)-like")|interpro:IPR003961(Fibronectin, type III)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR013320(Concanavalin A-like lectin/glucanase, subgroup)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR017903|interpro:IPR017907|interpro:IPR027370|interpro:IPR035731|interpro:IPR036116|interpro:IPR040859|interpro:IPR043136|mint:Q7TNM2 intact:EBI-25507525(chain-parent) - - chain-seq-start:5983|chain-seq-end:6503 figure legend:T1|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) - 2020/04/09 2020/04/11 rogid:W/Zpw91YDw+XPdzjyY9OvQECCfI10090 rogid:3yTbgNOOBsNHRdvI81i3BU1eN3w11142 rigid:+18wFbM/giXaIwzNTve4Ut/puQI false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:O08992 uniprotkb:P0C6X9-PRO_0000037347 intact:EBI-538265|uniprotkb:A2AKJ7|uniprotkb:Q544P5|ensembl:ENSMUSP00000029912 intact:EBI-25508415 psi-mi:sdcb1_mouse(display_long)|uniprotkb:Syndecan-binding protein 1(gene name synonym)|uniprotkb:Scaffold protein Pbp1(gene name synonym)|uniprotkb:Sdcbp(gene name)|psi-mi:Sdcbp(display_short) psi-mi:p0c6x9-pro_0000037347(display_long)|uniprotkb:rep(gene name)|psi-mi:rep(display_short)|uniprotkb:ORF1ab polyprotein(gene name synonym)|uniprotkb:1a-1b(orf name) psi-mi:"MI:0398"(two hybrid pooling approach) Vidalain et al. (2014) imex:IM-27904|pubmed:25720483 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:11142(cvma5)|taxid:11142("Murine coronavirus (strain A59)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-25508411|imex:IM-27904-25 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001091697.1|refseq:NP_058087.2|refseq:XP_006538147.1|reactome:R-MMU-5213460|reactome:R-MMU-5675482|reactome:R-MMU-6798695|reactome:R-MMU-447043|ensembl:ENSMUSG00000028249(gene)|ensembl:ENSMUST00000029912(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0002091"(negative regulation of receptor internalization)|go:"GO:0005109"(frizzled binding)|go:"GO:0005137"(interleukin-5 receptor binding)|go:"GO:0005546"(phosphatidylinositol-4,5-bisphosphate binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005886"(plasma membrane)|go:"GO:0005895"(interleukin-5 receptor complex)|go:"GO:0005912"(adherens junction)|go:"GO:0005925"(focal adhesion)|go:"GO:0007265"(Ras protein signal transduction)|go:"GO:0007268"(chemical synaptic transmission)|go:"GO:0007346"(regulation of mitotic cell cycle)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0010718"(positive regulation of epithelial to mesenchymal transition)|go:"GO:0010862"(positive regulation of pathway-restricted SMAD protein phosphorylation)|go:"GO:0019838"(growth factor binding)|go:"GO:0030036"(actin cytoskeleton organization)|go:"GO:0030307"(positive regulation of cell growth)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0030511"(positive regulation of transforming growth factor beta receptor signaling pathway)|go:"GO:0031965"(nuclear membrane)|go:"GO:0032435"(negative regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0042043"(neurexin family protein binding)|go:"GO:0042327"(positive regulation of phosphorylation)|go:"GO:0042470"(melanosome)|go:"GO:0042802"(identical protein binding)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045121"(membrane raft)|go:"GO:0045202"(synapse)|go:"GO:0045545"(syndecan binding)|go:"GO:0046875"(ephrin receptor binding)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0047485"(protein N-terminus binding)|go:"GO:0050839"(cell adhesion molecule binding)|go:"GO:0070062"(extracellular exosome)|go:"GO:0099054"(presynapse assembly)|go:"GO:1903543"(positive regulation of exosomal secretion)|go:"GO:1903553"(positive regulation of extracellular exosome assembly)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR030528|interpro:IPR036034|mint:O08992|reactome:R-MMU-3928664 intact:EBI-25507525(chain-parent) - - chain-seq-start:4318|chain-seq-end:4454 figure legend:T1|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) - 2020/04/09 2020/04/11 rogid:/hMRO9ZA+m3lU6+RgIvyEr/a1+w10090 rogid:hI0nsWGChYb5faUgimmzjZVJX+g11142 rigid:3L25OsdvQRu50lY9vWCaWAyV6Cw false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:P55264 uniprotkb:P0C6X9-PRO_0000037346 intact:EBI-7770144|ensembl:ENSMUSP00000047665|intact:MINT-1854964|uniprotkb:Q6JAM3|uniprotkb:Q91VJ3 intact:EBI-25508421 psi-mi:adk_mouse(display_long)|uniprotkb:Adk(gene name)|psi-mi:Adk(display_short)|uniprotkb:Adenosine 5'-phosphotransferase(gene name synonym) psi-mi:p0c6x9-pro_0000037346(display_long)|uniprotkb:rep(gene name)|psi-mi:rep(display_short)|uniprotkb:ORF1ab polyprotein(gene name synonym)|uniprotkb:1a-1b(orf name) psi-mi:"MI:0398"(two hybrid pooling approach) Vidalain et al. (2014) imex:IM-27904|pubmed:25720483 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:11142(cvma5)|taxid:11142("Murine coronavirus (strain A59)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-25508427|imex:IM-27904-27 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000039197(gene)|ensembl:ENSMUST00000045376(transcript)|go:"GO:0004001"(adenosine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006166"(purine ribonucleoside salvage)|go:"GO:0006175"(dATP biosynthetic process)|go:"GO:0010613"(positive regulation of cardiac muscle hypertrophy)|go:"GO:0042102"(positive regulation of T cell proliferation)|go:"GO:0044209"(AMP salvage)|go:"GO:0044342"(type B pancreatic cell proliferation)|go:"GO:0046085"(adenosine metabolic process)|go:"GO:0046872"(metal ion binding)|interpro:IPR001805(Adenosine kinase)|interpro:IPR002173(Carbohydrate/puine kinase, PfkB, conserved site)|interpro:IPR011611(Carbohydrate/purine kinase)|interpro:IPR029056|mint:P55264|rcsb pdb:5KB5|rcsb pdb:5KB6|reactome:R-MMU-74217|refseq:NP_598840.1|refseq:NP_001229970.1 intact:EBI-25507525(chain-parent) - comment:mint|function:ATP dependent phosphorylation of adenosine and other related nucleoside analogs to monophosphate derivatives. Serves as a potential regulator of concentrations of extracellular adenosine and intracellular adenine nucleotides chain-seq-start:4208|chain-seq-end:4317 figure legend:T1|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) - 2020/04/09 2020/04/11 rogid:1vQm3iESSi1E8ldip1P2DISmzaE10090 rogid:4GWtz0lKE0TpxTbOyiubqQdzZLI11142 rigid:pPDlit+s/xIcfV3fm4e8XQ1jFMI false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:P97434 uniprotkb:P0C6X9-PRO_0000037350 intact:EBI-2365654|uniprotkb:Q3TBR5|uniprotkb:Q3TC85|uniprotkb:Q3TRS0|uniprotkb:Q3U1Y8|uniprotkb:Q3U3E4|uniprotkb:Q5SWZ3|uniprotkb:Q5SWZ4|uniprotkb:Q5SWZ7|uniprotkb:Q6P559|uniprotkb:Q80YC8|ensembl:ENSMUSP00000112072 intact:EBI-25508339 psi-mi:mprip_mouse(display_long)|uniprotkb:Mprip(gene name)|psi-mi:Mprip(display_short)|uniprotkb:Kiaa0864(gene name synonym)|uniprotkb:Mrip(gene name synonym)|uniprotkb:Rhoip3(gene name synonym)|uniprotkb:Rho-interacting protein 3(gene name synonym)|uniprotkb:p116Rip(gene name synonym) psi-mi:p0c6x9-pro_0000037350(display_long)|uniprotkb:rep(gene name)|psi-mi:rep(display_short)|uniprotkb:ORF1ab polyprotein(gene name synonym)|uniprotkb:1a-1b(orf name) psi-mi:"MI:0398"(two hybrid pooling approach) Vidalain et al. (2014) imex:IM-27904|pubmed:25720483 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:11142(cvma5)|taxid:11142("Murine coronavirus (strain A59)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-25508431|imex:IM-27904-29 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_036157.2|refseq:NP_957697.1|refseq:XP_006533503.1|ensembl:ENSMUSG00000005417(gene)|ensembl:ENSMUST00000116371(transcript)|go:"GO:0001725"(stress fiber)|go:"GO:0001934"(positive regulation of protein phosphorylation)|go:"GO:0005829"(cytosol)|go:"GO:0007015"(actin filament organization)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0032507"(maintenance of protein location in cell)|go:"GO:0035509"(negative regulation of myosin-light-chain-phosphatase activity)|go:"GO:0051015"(actin filament binding)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR039597|mint:P97434 intact:EBI-25507525(chain-parent) - - chain-seq-start:5983|chain-seq-end:6503 figure legend:T1|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) - 2020/04/09 2020/04/11 rogid:jwOKcVLEosfXdMVQ5LfEjkan/U410090 rogid:3yTbgNOOBsNHRdvI81i3BU1eN3w11142 rigid:T5Gj47mtBdVc0W2FNVDs0z6iG5Y false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q8BIJ7 uniprotkb:P0C6X9-PRO_0000037346 intact:EBI-647341|uniprotkb:Q8BKQ4|uniprotkb:Q8BL21|uniprotkb:Q9EPM6|ensembl:ENSMUSP00000020643 intact:EBI-25508421 psi-mi:rufy1_mouse(display_long)|uniprotkb:Rab4-interacting protein(gene name synonym)|uniprotkb:Rufy1(gene name)|psi-mi:Rufy1(display_short)|uniprotkb:Rabip4(gene name synonym) psi-mi:p0c6x9-pro_0000037346(display_long)|uniprotkb:rep(gene name)|psi-mi:rep(display_short)|uniprotkb:ORF1ab polyprotein(gene name synonym)|uniprotkb:1a-1b(orf name) psi-mi:"MI:0398"(two hybrid pooling approach) Vidalain et al. (2014) imex:IM-27904|pubmed:25720483 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:11142(cvma5)|taxid:11142("Murine coronavirus (strain A59)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-25508435|imex:IM-27904-31 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_766145.1|go:"GO:0046872"(metal ion binding)|interpro:IPR000306(Zinc finger, FYVE-type)|interpro:IPR004012(RUN)|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017455(Zinc finger, FYVE-related)|interpro:IPR037213|mint:Q8BIJ7|reactome:R-MMU-1660499|go:"GO:0043231"(intracellular membrane-bounded organelle)|ensembl:ENSMUSG00000020375(gene)|ensembl:ENSMUST00000020643(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0005768"(endosome)|go:"GO:0006897"(endocytosis)|go:"GO:0007264"(small GTPase mediated signal transduction)|go:"GO:0008289"(lipid binding)|go:"GO:0015031"(protein transport)|go:"GO:0016607"(nuclear speck)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0030100"(regulation of endocytosis)|go:"GO:0031901"(early endosome membrane)|go:"GO:0042169"(SH2 domain binding)|go:"GO:0042802"(identical protein binding) intact:EBI-25507525(chain-parent) - - chain-seq-start:4208|chain-seq-end:4317 figure legend:T1|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) - 2020/04/09 2020/04/11 rogid:9ro2MkObt9rpc4AOzvM0Q9hK4Co10090 rogid:4GWtz0lKE0TpxTbOyiubqQdzZLI11142 rigid:xFu74tYZKpfymzfBPK+uZ3qTwyk false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q9JIY5 uniprotkb:P0C6X9-PRO_0000037346 intact:EBI-2365838|uniprotkb:Q9R108|ensembl:ENSMUSP00000087073 intact:EBI-25508421 psi-mi:htra2_mouse(display_long)|uniprotkb:Htra2(gene name)|psi-mi:Htra2(display_short)|uniprotkb:Omi(gene name synonym)|uniprotkb:Prss25(gene name synonym)|uniprotkb:High temperature requirement protein A2(gene name synonym)|uniprotkb:Omi stress-regulated endoprotease(gene name synonym)|uniprotkb:Serine proteinase OMI(gene name synonym)|uniprotkb:Serine protease 25(gene name synonym) psi-mi:p0c6x9-pro_0000037346(display_long)|uniprotkb:rep(gene name)|psi-mi:rep(display_short)|uniprotkb:ORF1ab polyprotein(gene name synonym)|uniprotkb:1a-1b(orf name) psi-mi:"MI:0398"(two hybrid pooling approach) Vidalain et al. (2014) imex:IM-27904|pubmed:25720483 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:11142(cvma5)|taxid:11142("Murine coronavirus (strain A59)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-25508439|imex:IM-27904-11 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_062726.3|dip:DIP-41272N|ensembl:ENSMUSG00000068329(gene)|ensembl:ENSMUST00000089645(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0004252"(serine-type endopeptidase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005739"(mitochondrion)|go:"GO:0005758"(mitochondrial intermembrane space)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0006508"(proteolysis)|go:"GO:0006672"(ceramide metabolic process)|go:"GO:0007005"(mitochondrion organization)|go:"GO:0007568"(aging)|go:"GO:0007628"(adult walking behavior)|go:"GO:0008233"(peptidase activity)|go:"GO:0008236"(serine-type peptidase activity)|go:"GO:0008344"(adult locomotory behavior)|go:"GO:0008630"(intrinsic apoptotic signaling pathway in response to DNA damage)|go:"GO:0009635"(response to herbicide)|go:"GO:0009898"(cytoplasmic side of plasma membrane)|go:"GO:0010822"(positive regulation of mitochondrion organization)|go:"GO:0012501"(programmed cell death)|go:"GO:0016020"(membrane)|go:"GO:0019742"(pentacyclic triterpenoid metabolic process)|go:"GO:0030900"(forebrain development)|go:"GO:0031966"(mitochondrial membrane)|go:"GO:0034599"(cellular response to oxidative stress)|go:"GO:0034605"(cellular response to heat)|go:"GO:0035458"(cellular response to interferon-beta)|go:"GO:0035631"(CD40 receptor complex)|go:"GO:0040014"(regulation of multicellular organism growth)|go:"GO:0042802"(identical protein binding)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043280"(positive regulation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0044257"(cellular protein catabolic process)|go:"GO:0048666"(neuron development)|go:"GO:0060548"(negative regulation of cell death)|go:"GO:0071300"(cellular response to retinoic acid)|go:"GO:0071363"(cellular response to growth factor stimulus)|go:"GO:0097193"(intrinsic apoptotic signaling pathway)|go:"GO:1904924"(negative regulation of mitophagy in response to mitochondrial depolarization)|go:"GO:1905370"(serine-type endopeptidase complex)|go:"GO:2001241"(positive regulation of extrinsic apoptotic signaling pathway in absence of ligand)|go:"GO:2001269"(positive regulation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR001940(Peptidase S1C, HrtA/DegP2/Q/S)|interpro:IPR009003(Peptidase, trypsin-like serine and cysteine)|interpro:IPR036034|interpro:IPR041489|mint:Q9JIY5 intact:EBI-25507525(chain-parent) - - chain-seq-start:4208|chain-seq-end:4317 figure legend:T1|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) - 2020/04/09 2020/04/11 rogid:hFFaMR4foetALMvFA0cg4KuxjuE10090 rogid:4GWtz0lKE0TpxTbOyiubqQdzZLI11142 rigid:akPrSiuk3YBeDTsmFP1Vw8QYWik false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:P12849 uniprotkb:P0C6X9-PRO_0000037345 intact:EBI-645585|ensembl:ENSMUSP00000026973|ensembl:ENSMUSP00000106515 intact:EBI-25508941 psi-mi:kap1_mouse(display_long)|uniprotkb:Prkar1b(gene name)|psi-mi:Prkar1b(display_short) psi-mi:p0c6x9-pro_0000037345(display_long)|uniprotkb:rep(gene name)|psi-mi:rep(display_short)|uniprotkb:ORF1ab polyprotein(gene name synonym)|uniprotkb:1a-1b(orf name) psi-mi:"MI:0398"(two hybrid pooling approach) Vidalain et al. (2014) imex:IM-27904|pubmed:25720483 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:11142(cvma5)|taxid:11142("Murine coronavirus (strain A59)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-25508937|imex:IM-27904-45 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_032949.3|refseq:XP_006504723.1|refseq:XP_006504724.1|refseq:XP_006504726.1|refseq:NP_001240819.1|refseq:XP_017176208.1|go:"GO:0010738"(regulation of protein kinase A signaling)|go:"GO:0030552"(cAMP binding)|go:"GO:0034236"(protein kinase A catalytic subunit binding)|go:"GO:0043949"(regulation of cAMP-mediated signaling)|go:"GO:0045202"(synapse)|go:"GO:0045859"(regulation of protein kinase activity)|go:"GO:0050804"(modulation of chemical synaptic transmission)|go:"GO:0098685"(Schaffer collateral - CA1 synapse)|go:"GO:0098686"(hippocampal mossy fiber to CA3 synapse)|go:"GO:0098693"(regulation of synaptic vesicle cycle)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:2000480"(negative regulation of cAMP-dependent protein kinase activity)|interpro:IPR000595(Cyclic nucleotide-binding)|interpro:IPR003117(cAMP-dependent protein kinase, regulatory subunit, type I/II alpha/beta)|interpro:IPR012198(cAMP-dependent protein kinase regulatory subunit)|interpro:IPR014710(RmlC-like jelly roll fold)|go:"GO:0009887"(animal organ morphogenesis)|interpro:IPR018488|interpro:IPR018490|interpro:IPR042818|mint:P12849|reactome:R-MMU-163615|reactome:R-MMU-164378|reactome:R-MMU-180024|reactome:R-MMU-432040|reactome:R-MMU-442720|reactome:R-MMU-5610787|reactome:R-MMU-983231|ensembl:ENSMUSG00000025855(gene)|ensembl:ENSMUST00000026973(transcript)|ensembl:ENSMUST00000110890(transcript)|go:"GO:0004862"(cAMP-dependent protein kinase inhibitor activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005771"(multivesicular body)|go:"GO:0005886"(plasma membrane)|go:"GO:0005952"(cAMP-dependent protein kinase complex)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0007611"(learning or memory)|go:"GO:0008603"(cAMP-dependent protein kinase regulator activity) intact:EBI-25507525(chain-parent) - - chain-seq-start:4014|chain-seq-end:4207 figure legend:T1|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) - 2020/04/09 2020/04/13 rogid:w65y6gB5uVAjfKjbAidQPpWtgAo10090 rogid:kDpfIuw/YEhnF47ZLFAbN6KCIOo11142 rigid:hjfRGeePYPHWdC83GEzccfPl3ZM false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q8BJU0 uniprotkb:P0C6X9-PRO_0000037344 intact:EBI-25508957|ensembl:ENSMUSP00000005067|uniprotkb:Q8BGA6|uniprotkb:Q99L52 intact:EBI-25508947 psi-mi:sgta_mouse(display_long)|uniprotkb:Sgta(gene name)|psi-mi:Sgta(display_short)|uniprotkb:Sgt(gene name synonym)|uniprotkb:Alpha-SGT(gene name synonym) psi-mi:p0c6x9-pro_0000037344(display_long)|uniprotkb:rep(gene name)|psi-mi:rep(display_short)|uniprotkb:ORF1ab polyprotein(gene name synonym)|uniprotkb:1a-1b(orf name) psi-mi:"MI:0398"(two hybrid pooling approach) Vidalain et al. (2014) imex:IM-27904|pubmed:25720483 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:11142(cvma5)|taxid:11142("Murine coronavirus (strain A59)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-25508953|imex:IM-27904-71 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000004937(gene)|ensembl:ENSMUST00000005067(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006620"(posttranslational protein targeting to endoplasmic reticulum membrane)|go:"GO:0016020"(membrane)|go:"GO:0030433"(ubiquitin-dependent ERAD pathway)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043621"(protein self-association)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0061077"(chaperone-mediated protein folding)|go:"GO:0071816"(tail-anchored membrane protein insertion into ER membrane)|go:"GO:0072380"(TRC complex)|go:"GO:0098793"(presynapse)|go:"GO:0098850"(extrinsic component of synaptic vesicle membrane)|go:"GO:1903070"(negative regulation of ER-associated ubiquitin-dependent protein catabolic process)|go:"GO:1903071"(positive regulation of ER-associated ubiquitin-dependent protein catabolic process)|go:"GO:1903646"(positive regulation of chaperone-mediated protein folding)|go:"GO:1904288"(BAT3 complex binding)|go:"GO:2000059"(negative regulation of ubiquitin-dependent protein catabolic process)|interpro:IPR001440(Tetratricopeptide TPR-1)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR019734|interpro:IPR032374|mint:Q8BJU0|reactome:R-MMU-9609523|refseq:NP_078775.1|refseq:XP_006513940.1|refseq:XP_017169518.1|refseq:XP_006513939.1 intact:EBI-25507525(chain-parent) - - chain-seq-start:3922|chain-seq-end:4013 figure legend:T1|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) - 2020/04/09 2020/04/13 rogid:6D04GHTvg0JkR7ngrj3xBXOoYeE10090 rogid:8yYIfFvCyyzoFln1A3JJa3X3brw11142 rigid:HAohsVJPRejmvjOHekFJUZzFJDg false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:P0C6X9-PRO_0000037344 uniprotkb:Q6P1G0 intact:EBI-25508947 intact:EBI-648075|uniprotkb:Q3UUN8|uniprotkb:Q99KZ5|uniprotkb:Q9CSQ4|ensembl:ENSMUSP00000001002 psi-mi:p0c6x9-pro_0000037344(display_long)|uniprotkb:rep(gene name)|psi-mi:rep(display_short)|uniprotkb:ORF1ab polyprotein(gene name synonym)|uniprotkb:1a-1b(orf name) psi-mi:heat6_mouse(display_long)|uniprotkb:Heatr6(gene name)|psi-mi:Heatr6(display_short) psi-mi:"MI:0398"(two hybrid pooling approach) Vidalain et al. (2014) imex:IM-27904|pubmed:25720483 taxid:11142(cvma5)|taxid:11142("Murine coronavirus (strain A59)") taxid:10090(mouse)|taxid:10090(Mus musculus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-25509000|imex:IM-27904-13 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) intact:EBI-25507525(chain-parent) refseq:NP_663407.2|ensembl:ENSMUSG00000000976(gene)|ensembl:ENSMUST00000001002(transcript)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR025283 - chain-seq-start:3922|chain-seq-end:4013 - figure legend:T1|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) - 2020/04/09 2020/04/13 rogid:8yYIfFvCyyzoFln1A3JJa3X3brw11142 rogid:MeIoA+j0crXcWqA2cYGHa7FcQhg10090 rigid:DVXBAcLty8j/eGAIPrl43Pb9FJY false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:O88907 uniprotkb:P0C6X9-PRO_0000037344 intact:EBI-3508327|uniprotkb:Q8C6H5|ensembl:ENSMUSP00000096248 intact:EBI-25508947 psi-mi:pias1_mouse(display_long)|uniprotkb:Pias1(gene name)|psi-mi:Pias1(display_short)|uniprotkb:Ddxbp1(gene name synonym)|uniprotkb:DEAD/H box-binding protein 1(gene name synonym)|uniprotkb:Protein inhibitor of activated STAT protein 1(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase PIAS1(gene name synonym) psi-mi:p0c6x9-pro_0000037344(display_long)|uniprotkb:rep(gene name)|psi-mi:rep(display_short)|uniprotkb:ORF1ab polyprotein(gene name synonym)|uniprotkb:1a-1b(orf name) psi-mi:"MI:0398"(two hybrid pooling approach) Vidalain et al. (2014) imex:IM-27904|pubmed:25720483 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:11142(cvma5)|taxid:11142("Murine coronavirus (strain A59)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-25509007|imex:IM-27904-47 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_062637.2|ensembl:ENSMUSG00000032405(gene)|ensembl:ENSMUST00000098651(transcript)|go:"GO:0000082"(G1/S transition of mitotic cell cycle)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0003677"(DNA binding)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007259"(receptor signaling pathway via JAK-STAT)|go:"GO:0007283"(spermatogenesis)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008134"(transcription factor binding)|go:"GO:0008270"(zinc ion binding)|go:"GO:0008542"(visual learning)|go:"GO:0016605"(PML body)|go:"GO:0016607"(nuclear speck)|go:"GO:0016925"(protein sumoylation)|go:"GO:0019789"(SUMO transferase activity)|go:"GO:0019899"(enzyme binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032436"(positive regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0033235"(positive regulation of protein sumoylation)|go:"GO:0042127"(regulation of cell population proliferation)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0045444"(fat cell differentiation)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0051152"(positive regulation of smooth muscle cell differentiation)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:0061665"(SUMO ligase activity)|go:"GO:0065004"(protein-DNA complex assembly)|interpro:IPR003034(DNA-binding SAP)|interpro:IPR004181(Zinc finger, MIZ-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR023321|interpro:IPR027226|interpro:IPR036361|interpro:IPR038654|mint:O88907|reactome:R-MMU-3108214|reactome:R-MMU-3232118|reactome:R-MMU-3232142|reactome:R-MMU-3899300|reactome:R-MMU-4090294|reactome:R-MMU-4551638|reactome:R-MMU-5696395|reactome:R-MMU-877312|dip:DIP-29277N intact:EBI-25507525(chain-parent) - - chain-seq-start:3922|chain-seq-end:4013 figure legend:T1|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) - 2020/04/09 2020/04/13 rogid:pQV24om+YlKv5s9bCIXobNpziRE10090 rogid:8yYIfFvCyyzoFln1A3JJa3X3brw11142 rigid:929Zkdp3YaKduLzgF1mx86lRcd0 false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q8C008 uniprotkb:P0C6X9-PRO_0000037342 intact:EBI-8317102|uniprotkb:Q8C060|intact:MINT-4113786|uniprotkb:A2AN93|ensembl:ENSMUSP00000080643 intact:EBI-25509011 psi-mi:dzan1_mouse(display_long)|uniprotkb:Dzank1(gene name)|psi-mi:Dzank1(display_short) psi-mi:p0c6x9-pro_0000037342(display_long)|uniprotkb:rep(gene name)|psi-mi:rep(display_short)|uniprotkb:ORF1ab polyprotein(gene name synonym)|uniprotkb:1a-1b(orf name) psi-mi:"MI:0398"(two hybrid pooling approach) Vidalain et al. (2014) imex:IM-27904|pubmed:25720483 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:11142(cvma5)|taxid:11142("Murine coronavirus (strain A59)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-25509017|imex:IM-27904-33 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_766447.2|ensembl:ENSMUSG00000037259(gene)|ensembl:ENSMUST00000081982(transcript)|go:"GO:0046872"(metal ion binding)|interpro:IPR025874|interpro:IPR026876|interpro:IPR036770|mint:Q8C008 intact:EBI-25507525(chain-parent) - comment:mint chain-seq-start:3334|chain-seq-end:3635 figure legend:T1|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) - 2020/04/09 2020/04/13 rogid:ozGQu95/TVKGDwRgLlTCq+bl3PM10090 rogid:sT1Vgm4rK1OfYX9i4src/cbLWsw11142 rigid:GJIdKG9I/RomEXzVwk6KIzRCxdw false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q8VHZ5 uniprotkb:P0C6X9-PRO_0000037342 intact:EBI-8538157|uniprotkb:Q8C0Z7|intact:UNK-5527033|uniprotkb:Q8VD49|uniprotkb:Q9CQV2|ensembl:ENSMUSP00000058896 intact:EBI-25509011 psi-mi:ddt4l_mouse(display_long)|uniprotkb:Ddit4l(gene name)|psi-mi:Ddit4l(display_short)|uniprotkb:Rtp801l(gene name synonym)|uniprotkb:Smhs1(gene name synonym)|uniprotkb:HIF-1 responsive protein RTP801-like(gene name synonym)|uniprotkb:Soleus muscle atrophied after hindlimb suspension protein 1(gene name synonym) psi-mi:p0c6x9-pro_0000037342(display_long)|uniprotkb:rep(gene name)|psi-mi:rep(display_short)|uniprotkb:ORF1ab polyprotein(gene name synonym)|uniprotkb:1a-1b(orf name) psi-mi:"MI:0398"(two hybrid pooling approach) Vidalain et al. (2014) imex:IM-27904|pubmed:25720483 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:11142(cvma5)|taxid:11142("Murine coronavirus (strain A59)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-25509023|imex:IM-27904-73 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_084419.2|ensembl:ENSMUSG00000046818(gene)|ensembl:ENSMUST00000053855(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0009968"(negative regulation of signal transduction)|interpro:IPR012918(RTP801, C-terminal)|interpro:IPR038281 intact:EBI-25507525(chain-parent) - comment:mint|function:Inhibits cell growth by regulating the FRAP1 pathway upstream of the TSC1-TSC2 complex and downstream of AKT1 chain-seq-start:3334|chain-seq-end:3635 figure legend:T1|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) - 2020/04/09 2020/04/13 rogid:oxhag8TWUrN6a0Q6Wg+LHsaU3i010090 rogid:sT1Vgm4rK1OfYX9i4src/cbLWsw11142 rigid:tm9yaLQf775/E2vfmvrkgWRsQik false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q9EQJ9 uniprotkb:P0C6X9-PRO_0000037342 intact:EBI-7455245|uniprotkb:Q8C0P8|intact:MINT-1894696|uniprotkb:B0V3N7|intact:UNK-5947369|uniprotkb:Q69ZE1|uniprotkb:B0V3N8 intact:EBI-25509011 psi-mi:magi3_mouse(display_long)|uniprotkb:Magi3(gene name)|psi-mi:Magi3(display_short)|uniprotkb:Membrane-associated guanylate kinase inverted 3(gene name synonym)|uniprotkb:Kiaa1634(gene name synonym) psi-mi:p0c6x9-pro_0000037342(display_long)|uniprotkb:rep(gene name)|psi-mi:rep(display_short)|uniprotkb:ORF1ab polyprotein(gene name synonym)|uniprotkb:1a-1b(orf name) psi-mi:"MI:0398"(two hybrid pooling approach) Vidalain et al. (2014) imex:IM-27904|pubmed:25720483 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:11142(cvma5)|taxid:11142("Murine coronavirus (strain A59)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-25509027|imex:IM-27904-75 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR030035|mint:Q9EQJ9|interpro:IPR036034|interpro:IPR036020|interpro:IPR020590|interpro:IPR027417|refseq:NP_598614.1|interpro:IPR001202(WW/Rsp5/WWP)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR008144(Guanylate kinase)|interpro:IPR008145(Guanylate kinase/L-type calcium channel region)|go:"GO:0005109"(frizzled binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005923"(bicellular tight junction)|go:"GO:0007165"(signal transduction)|go:"GO:0030054"(cell junction)|go:"GO:0043507"(positive regulation of JUN kinase activity)|go:"GO:0046328"(regulation of JNK cascade)|go:"GO:0060090"(molecular adaptor activity) intact:EBI-25507525(chain-parent) - comment:mint chain-seq-start:3334|chain-seq-end:3635 figure legend:T1|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) - 2020/04/09 2020/04/13 rogid:LbFYUmxao9TmprW22YUA3GS9nCs10090 rogid:sT1Vgm4rK1OfYX9i4src/cbLWsw11142 rigid:2ucmSAwZ5BBfu3cbT3buwULFQBE false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q8K296 uniprotkb:P0C6X9-PRO_0000037342 intact:EBI-25509031|uniprotkb:Q5NCA4 intact:EBI-25509011 psi-mi:mtmr3_mouse(display_long)|uniprotkb:Mtmr3(gene name)|psi-mi:Mtmr3(display_short)|uniprotkb:Phosphatidylinositol-3,5-bisphosphate 3-phosphatase(gene name synonym)|uniprotkb:Phosphatidylinositol-3-phosphate phosphatase(gene name synonym) psi-mi:p0c6x9-pro_0000037342(display_long)|uniprotkb:rep(gene name)|psi-mi:rep(display_short)|uniprotkb:ORF1ab polyprotein(gene name synonym)|uniprotkb:1a-1b(orf name) psi-mi:"MI:0398"(two hybrid pooling approach) Vidalain et al. (2014) imex:IM-27904|pubmed:25720483 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:11142(cvma5)|taxid:11142("Murine coronavirus (strain A59)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-25509065|imex:IM-27904-15 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0004438"(phosphatidylinositol-3-phosphatase activity)|go:"GO:0004722"(protein serine/threonine phosphatase activity)|go:"GO:0004725"(protein tyrosine phosphatase activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0006470"(protein dephosphorylation)|go:"GO:0008138"(protein tyrosine/serine/threonine phosphatase activity)|go:"GO:0010506"(regulation of autophagy)|go:"GO:0016020"(membrane)|go:"GO:0019898"(extrinsic component of membrane)|go:"GO:0019903"(protein phosphatase binding)|go:"GO:0042149"(cellular response to glucose starvation)|go:"GO:0046856"(phosphatidylinositol dephosphorylation)|go:"GO:0046872"(metal ion binding)|go:"GO:0052629"(phosphatidylinositol-3,5-bisphosphate 3-phosphatase activity)|go:"GO:0060304"(regulation of phosphatidylinositol dephosphorylation)|go:"GO:1904562"(phosphatidylinositol 5-phosphate metabolic process)|go:"GO:2000785"(regulation of autophagosome assembly)|refseq:XP_006514910.1|reactome:R-MMU-1632852|reactome:R-MMU-1660499|interpro:IPR035888|interpro:IPR010569(Myotubularin-related)|interpro:IPR030564|interpro:IPR029021|interpro:IPR016130(Protein-tyrosine phosphatase, active site)|interpro:IPR003595(Protein-tyrosine phosphatase, catalytic)|interpro:IPR000306(Zinc finger, FYVE-type)|interpro:IPR017455(Zinc finger, FYVE-related)|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type) intact:EBI-25507525(chain-parent) - - chain-seq-start:3334|chain-seq-end:3635 figure legend:T1|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) - 2020/04/09 2020/04/13 rogid:rWtR7duAM25UEakH4cNHrc0tKgI10090 rogid:sT1Vgm4rK1OfYX9i4src/cbLWsw11142 rigid:1kdV4Lwhq3tsZAGiCoSeFjMHJpI false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:O88888 uniprotkb:P0C6X9-PRO_0000037342 intact:EBI-25509069|ensembl:ENSMUSP00000050995|ensembl:ENSMUSP00000151985|uniprotkb:Q3TDI1|uniprotkb:Q8BR09 intact:EBI-25509011 psi-mi:apba3_mouse(display_long)|uniprotkb:Apba3(gene name)|psi-mi:Apba3(display_short)|uniprotkb:Mint3(gene name synonym)|uniprotkb:Adapter protein X11gamma(gene name synonym)|uniprotkb:Neuron-specific X11L2 protein(gene name synonym)|uniprotkb:Neuronal Munc18-1-interacting protein 3(gene name synonym) psi-mi:p0c6x9-pro_0000037342(display_long)|uniprotkb:rep(gene name)|psi-mi:rep(display_short)|uniprotkb:ORF1ab polyprotein(gene name synonym)|uniprotkb:1a-1b(orf name) psi-mi:"MI:0398"(two hybrid pooling approach) Vidalain et al. (2014) imex:IM-27904|pubmed:25720483 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:11142(cvma5)|taxid:11142("Murine coronavirus (strain A59)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-25509102|imex:IM-27904-49 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUST00000057798(transcript)|ensembl:ENSMUST00000220297(transcript)|go:"GO:0001540"(amyloid-beta binding)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0004857"(enzyme inhibitor activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0007268"(chemical synaptic transmission)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0015031"(protein transport)|go:"GO:0019899"(enzyme binding)|go:"GO:0043086"(negative regulation of catalytic activity)|go:"GO:0043197"(dendritic spine)|go:"GO:0048471"(perinuclear region of cytoplasm)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR006020(Phosphotyrosine interaction region)|ensembl:ENSMUSG00000004931(gene)|interpro:IPR030531|interpro:IPR036034|interpro:IPR011993(Pleckstrin homology-type)|refseq:NP_061228.1|refseq:XP_006513968.1|refseq:XP_006513969.1 intact:EBI-25507525(chain-parent) - - chain-seq-start:3334|chain-seq-end:3635 figure legend:T1|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) - 2020/04/09 2020/04/13 rogid:dUQ/jVIHPdseqztrKJWWpg87/ew10090 rogid:sT1Vgm4rK1OfYX9i4src/cbLWsw11142 rigid:a9zhANGjuasITYN7+5gZ2MiccZ0 false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q8BMJ7 uniprotkb:P0C6X9-PRO_0000037342 intact:EBI-25509106|ensembl:ENSMUSP00000070548|uniprotkb:Q3U3F1|uniprotkb:Q8CI24 intact:EBI-25509011 psi-mi:cgrf1_mouse(display_long)|uniprotkb:Cgrrf1(gene name)|psi-mi:Cgrrf1(display_short)|uniprotkb:Cgr19(gene name synonym)|uniprotkb:Cell growth regulatory gene 19 protein(gene name synonym) psi-mi:p0c6x9-pro_0000037342(display_long)|uniprotkb:rep(gene name)|psi-mi:rep(display_short)|uniprotkb:ORF1ab polyprotein(gene name synonym)|uniprotkb:1a-1b(orf name) psi-mi:"MI:0398"(two hybrid pooling approach) Vidalain et al. (2014) imex:IM-27904|pubmed:25720483 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:11142(cvma5)|taxid:11142("Murine coronavirus (strain A59)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-25509127|imex:IM-27904-17 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000055128(gene)|ensembl:ENSMUST00000068532(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0007049"(cell cycle)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0046872"(metal ion binding)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR042496|refseq:NP_081108.2|refseq:XP_006519548.1 intact:EBI-25507525(chain-parent) - - chain-seq-start:3334|chain-seq-end:3635 figure legend:T1|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) - 2020/04/09 2020/04/13 rogid:2twqPVBBwx8yUVkSoiFQccuo/ns10090 rogid:sT1Vgm4rK1OfYX9i4src/cbLWsw11142 rigid:gu/Om0wQz6nq4Y5daH1UvlQqro4 false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:P59280 uniprotkb:P0C6X9-PRO_0000037342 intact:EBI-25509131|ensembl:ENSMUSP00000031254|uniprotkb:Q8CD84 intact:EBI-25509011 psi-mi:klhl8_mouse(display_long)|uniprotkb:Klhl8(gene name)|psi-mi:Klhl8(display_short) psi-mi:p0c6x9-pro_0000037342(display_long)|uniprotkb:rep(gene name)|psi-mi:rep(display_short)|uniprotkb:ORF1ab polyprotein(gene name synonym)|uniprotkb:1a-1b(orf name) psi-mi:"MI:0398"(two hybrid pooling approach) Vidalain et al. (2014) imex:IM-27904|pubmed:25720483 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:11142(cvma5)|taxid:11142("Murine coronavirus (strain A59)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-25509153|imex:IM-27904-51 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000029312(gene)|ensembl:ENSMUST00000031254(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0031463"(Cul3-RING ubiquitin ligase complex)|interpro:IPR000210(BTB/POZ-like)|interpro:IPR006652(Kelch repeat type 1)|interpro:IPR011333(BTB/POZ fold)|interpro:IPR011705(BTB/Kelch-associated)|interpro:IPR015915(Kelch-type beta propeller)|interpro:IPR017096(Kelch-like protein, gigaxonin)|interpro:IPR030605|refseq:NP_848856.1|refseq:XP_006535005.1|refseq:XP_017176372.1 intact:EBI-25507525(chain-parent) - - chain-seq-start:3334|chain-seq-end:3635 figure legend:T1|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) - 2020/04/09 2020/04/13 rogid:U/AaQhbtOKDCkrVlnkUykexnowc10090 rogid:sT1Vgm4rK1OfYX9i4src/cbLWsw11142 rigid:y8NCxfW2OKO5J5ur7fhvvgkr8fE false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q05512 uniprotkb:P0C6X9-PRO_0000037339 intact:EBI-771728|uniprotkb:Q3T9L3|uniprotkb:Q6PDR4|uniprotkb:Q8BR95 intact:EBI-25509157 psi-mi:mark2_mouse(display_long)|uniprotkb:MAP/microtubule affinity-regulating kinase 2(gene name synonym)|uniprotkb:ELKL motif kinase 1(gene name synonym)|uniprotkb:Mark2(gene name)|psi-mi:Mark2(display_short)|uniprotkb:Emk(gene name synonym)|uniprotkb:PAR1 homolog(gene name synonym)|uniprotkb:PAR1 homolog b(gene name synonym) psi-mi:p0c6x9-pro_0000037339(display_long)|uniprotkb:rep(gene name)|psi-mi:rep(display_short)|uniprotkb:ORF1ab polyprotein(gene name synonym)|uniprotkb:1a-1b(orf name) psi-mi:"MI:0398"(two hybrid pooling approach) Vidalain et al. (2014) imex:IM-27904|pubmed:25720483 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:11142(cvma5)|taxid:11142("Murine coronavirus (strain A59)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-25509163|imex:IM-27904-35 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001073857.1|refseq:NP_001073858.1|refseq:NP_001073859.1|refseq:NP_031954.2|interpro:IPR001772(Kinase-associated KA1)|interpro:IPR011009(Protein kinase-like)|interpro:IPR000719(Protein kinase, core)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR015940(Ubiquitin-associated/translation elongation factor EF1B, N-terminal, eukaryote)|interpro:IPR028375|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0000287"(magnesium ion binding)|go:"GO:0001764"(neuron migration)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005884"(actin filament)|go:"GO:0005886"(plasma membrane)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0008289"(lipid binding)|go:"GO:0010976"(positive regulation of neuron projection development)|go:"GO:0016020"(membrane)|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0016328"(lateral plasma membrane)|go:"GO:0018105"(peptidyl-serine phosphorylation)|go:"GO:0030010"(establishment of cell polarity)|go:"GO:0030425"(dendrite)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0045180"(basal cortex)|go:"GO:0045197"(establishment or maintenance of epithelial cell apical/basal polarity)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0047485"(protein N-terminus binding)|go:"GO:0048156"(tau protein binding)|go:"GO:0050321"(tau-protein kinase activity)|go:"GO:0050770"(regulation of axonogenesis)|go:"GO:0051493"(regulation of cytoskeleton organization)|go:"GO:0061564"(axon development)|go:"GO:0070507"(regulation of microtubule cytoskeleton organization)|go:"GO:0071963"(establishment or maintenance of cell polarity regulating cell shape)|go:"GO:0097427"(microtubule bundle)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:1904526"(regulation of microtubule binding) intact:EBI-25507525(chain-parent) - - chain-seq-start:248|chain-seq-end:832 figure legend:T1|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) - 2020/04/09 2020/04/13 rogid:RiipGX3uA3cvQACWclxzpLcJQVU10090 rogid:cid4WByklSo+DS1gVUCDUYXYOB411142 rigid:uxVs7b5EpbmtCn83oVWAfG8KWCw false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q8VHJ5 uniprotkb:P0C6X9-PRO_0000037339 intact:EBI-2933584|uniprotkb:E9QL17|ensembl:ENSMUSP00000027929|uniprotkb:Q69ZI7 intact:EBI-25509157 psi-mi:mark1_mouse(display_long)|uniprotkb:Mark1(gene name)|psi-mi:Mark1(display_short)|uniprotkb:Emk3(gene name synonym)|uniprotkb:Kiaa1477(gene name synonym)|uniprotkb:ELKL motif serine/threonine-protein kinase 3(gene name synonym)|uniprotkb:MAP/microtubule affinity-regulating kinase 1(gene name synonym)|uniprotkb:PAR1 homolog c(gene name synonym) psi-mi:p0c6x9-pro_0000037339(display_long)|uniprotkb:rep(gene name)|psi-mi:rep(display_short)|uniprotkb:ORF1ab polyprotein(gene name synonym)|uniprotkb:1a-1b(orf name) psi-mi:"MI:0398"(two hybrid pooling approach) Vidalain et al. (2014) imex:IM-27904|pubmed:25720483 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:11142(cvma5)|taxid:11142("Murine coronavirus (strain A59)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-25509167|imex:IM-27904-53 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000026620(gene)|ensembl:ENSMUST00000027929(transcript)|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0000287"(magnesium ion binding)|go:"GO:0001764"(neuron migration)|go:"GO:0001786"(phosphatidylserine binding)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005546"(phosphatidylinositol-4,5-bisphosphate binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005886"(plasma membrane)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0007010"(cytoskeleton organization)|go:"GO:0010975"(regulation of neuron projection development)|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0030425"(dendrite)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0050321"(tau-protein kinase activity)|go:"GO:0050773"(regulation of dendrite development)|go:"GO:0051654"(establishment of mitochondrion localization)|go:"GO:0070300"(phosphatidic acid binding)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0004672"(protein kinase activity)|go:"GO:0106311"|interpro:IPR000719(Protein kinase, core)|interpro:IPR001772(Kinase-associated KA1)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR015940(Ubiquitin-associated/translation elongation factor EF1B, N-terminal, eukaryote)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR028375|interpro:IPR033627|mint:Q8VHJ5|refseq:NP_663490.2 intact:EBI-25507525(chain-parent) - - chain-seq-start:248|chain-seq-end:832 figure legend:T1|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) - 2020/04/09 2020/04/13 rogid:hEqQq7idcvJl3Vv/xr7k+EC61Jo10090 rogid:cid4WByklSo+DS1gVUCDUYXYOB411142 rigid:OwgZrPLwlZTZs/pinozJWsJ7b04 false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q03141 uniprotkb:P0C6X9-PRO_0000037339 intact:EBI-6271614|ensembl:ENSMUSP00000152483|uniprotkb:Q3TM40|uniprotkb:Q3V1U3|uniprotkb:Q8C6G9|uniprotkb:Q8R375|uniprotkb:Q9JKE4 intact:EBI-25509157 psi-mi:mark3_mouse(display_long)|uniprotkb:Mark3(gene name)|psi-mi:Mark3(display_short)|uniprotkb:Emk2(gene name synonym)|uniprotkb:Mpk10(gene name synonym)|uniprotkb:ELKL motif kinase 2(gene name synonym)|uniprotkb:MPK-10(gene name synonym) psi-mi:p0c6x9-pro_0000037339(display_long)|uniprotkb:rep(gene name)|psi-mi:rep(display_short)|uniprotkb:ORF1ab polyprotein(gene name synonym)|uniprotkb:1a-1b(orf name) psi-mi:"MI:0398"(two hybrid pooling approach) Vidalain et al. (2014) imex:IM-27904|pubmed:25720483 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:11142(cvma5)|taxid:11142("Murine coronavirus (strain A59)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-25509171|imex:IM-27904-37 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000007411(gene)|ensembl:ENSMUST00000221459(transcript)|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0018105"(peptidyl-serine phosphorylation)|go:"GO:0030425"(dendrite)|go:"GO:0032092"(positive regulation of protein binding)|go:"GO:0035331"(negative regulation of hippo signaling)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0036289"(peptidyl-serine autophosphorylation)|go:"GO:0050321"(tau-protein kinase activity)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000719(Protein kinase, core)|interpro:IPR001772(Kinase-associated KA1)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR015940(Ubiquitin-associated/translation elongation factor EF1B, N-terminal, eukaryote)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR028375|interpro:IPR033628|rcsb pdb:1UL7|rcsb pdb:1V5S|reactome:R-MMU-5673000|reactome:R-MMU-5674135|reactome:R-MMU-5675221|refseq:XP_006515578.1|refseq:NP_067491.2|refseq:NP_073712.2 intact:EBI-25507525(chain-parent) - - chain-seq-start:248|chain-seq-end:832 figure legend:T1|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) - 2020/04/09 2020/04/13 rogid:HW82JxS22iNaXpgoeug0FOrMRmM10090 rogid:cid4WByklSo+DS1gVUCDUYXYOB411142 rigid:yc3yLops2xSC0BVBOXXF10pRZU4 false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q8BMK0 uniprotkb:P0C6X9-PRO_0000037339 intact:EBI-11091136|uniprotkb:Q8BUF1|uniprotkb:Q8K0E6|ensembl:ENSMUSP00000039889 intact:EBI-25509157 psi-mi:cep85_mouse(display_long)|uniprotkb:Cep85(gene name)|psi-mi:Cep85(display_short)|uniprotkb:Ccdc21(gene name synonym)|uniprotkb:Coiled-coil domain-containing protein 21(gene name synonym) psi-mi:p0c6x9-pro_0000037339(display_long)|uniprotkb:rep(gene name)|psi-mi:rep(display_short)|uniprotkb:ORF1ab polyprotein(gene name synonym)|uniprotkb:1a-1b(orf name) psi-mi:"MI:0398"(two hybrid pooling approach) Vidalain et al. (2014) imex:IM-27904|pubmed:25720483 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:11142(cvma5)|taxid:11142("Murine coronavirus (strain A59)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-25509175|imex:IM-27904-55 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_653110.3|refseq:XP_011248632.1|ensembl:ENSMUSG00000037443(gene)|ensembl:ENSMUST00000040271(transcript)|go:"GO:0000242"(pericentriolar material)|go:"GO:0000922"(spindle pole)|go:"GO:0001764"(neuron migration)|go:"GO:0005730"(nucleolus)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0006469"(negative regulation of protein kinase activity)|go:"GO:0007059"(chromosome segregation)|go:"GO:0046602"(regulation of mitotic centrosome separation)|interpro:IPR029777|interpro:IPR040210 intact:EBI-25507525(chain-parent) - - chain-seq-start:248|chain-seq-end:832 figure legend:T1|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) - 2020/04/09 2020/04/13 rogid:eiAUTM3H109tpcoE+5LdSB7G2zE10090 rogid:cid4WByklSo+DS1gVUCDUYXYOB411142 rigid:Bxuzk8MQltkPjBqUk5hOueWlnBA false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:O35231 uniprotkb:P0C6X9-PRO_0000037340 intact:EBI-11097964|ensembl:ENSMUSP00000034240|uniprotkb:O35072|uniprotkb:Q99KP7|uniprotkb:Q91YQ2|uniprotkb:Q8R3Y4|uniprotkb:Q6NS71|uniprotkb:Q3V0U4|uniprotkb:Q1WNZ8|uniprotkb:Q3UX36 intact:EBI-25509188 psi-mi:kifc3_mouse(display_long)|uniprotkb:Kifc3(gene name)|psi-mi:Kifc3(display_short) psi-mi:p0c6x9-pro_0000037340(display_long)|uniprotkb:rep(gene name)|psi-mi:rep(display_short)|uniprotkb:ORF1ab polyprotein(gene name synonym)|uniprotkb:1a-1b(orf name) psi-mi:"MI:0398"(two hybrid pooling approach) Vidalain et al. (2014) imex:IM-27904|pubmed:25720483 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:11142(cvma5)|taxid:11142("Murine coronavirus (strain A59)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-25509183|imex:IM-27904-19 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000031788(gene)|ensembl:ENSMUST00000034240(transcript)|go:"GO:0005524"(ATP binding)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005813"(centrosome)|go:"GO:0005871"(kinesin complex)|go:"GO:0005874"(microtubule)|go:"GO:0005915"(zonula adherens)|go:"GO:0007017"(microtubule-based process)|go:"GO:0007018"(microtubule-based movement)|go:"GO:0007030"(Golgi organization)|go:"GO:0008017"(microtubule binding)|go:"GO:0008569"(minus-end-directed microtubule motor activity)|go:"GO:0030659"(cytoplasmic vesicle membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0045218"(zonula adherens maintenance)|go:"GO:0090136"(epithelial cell-cell adhesion)|interpro:IPR001752(Kinesin, motor region)|interpro:IPR019821|interpro:IPR027325|interpro:IPR027417|refseq:NP_001139303.1|refseq:NP_001139304.1|refseq:NP_034761.3|interpro:IPR036961 intact:EBI-25507525(chain-parent) - - chain-seq-start:833|chain-seq-end:2837 figure legend:T1|comment:"The very large nsp3 was divided into three parts of approximately similar size (nsp3a, 3b, and 3c). In total, 15 MHV full-length proteins or isolated domains (including nsp3a and 3b) were used as bait to screen a mouse brain cDNA library."|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) - 2020/04/09 2020/04/13 rogid:yITFB8eRxWjo4hJ4SZV4lOpn1RM10090 rogid:/X+hmk/7yCyCykKykcDQ4x7OBSs11142 rigid:6HhgNbB7mEMu4r5Z0/iCg4xyRWs false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q8VHH5 uniprotkb:P0C6X9-PRO_0000037340 intact:EBI-25509196|uniprotkb:Q812F7 intact:EBI-25509188 psi-mi:agap3_mouse(display_long)|uniprotkb:Agap3(gene name)|psi-mi:Agap3(display_short)|uniprotkb:Centg3(gene name synonym)|uniprotkb:CRAM-associated GTPase(gene name synonym)|uniprotkb:Centaurin-gamma-3(gene name synonym)|uniprotkb:MR1-interacting protein(gene name synonym) psi-mi:p0c6x9-pro_0000037340(display_long)|uniprotkb:rep(gene name)|psi-mi:rep(display_short)|uniprotkb:ORF1ab polyprotein(gene name synonym)|uniprotkb:1a-1b(orf name) psi-mi:"MI:0398"(two hybrid pooling approach) Vidalain et al. (2014) imex:IM-27904|pubmed:25720483 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:11142(cvma5)|taxid:11142("Murine coronavirus (strain A59)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-25509226|imex:IM-27904-57 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0003924"(GTPase activity)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0007165"(signal transduction)|go:"GO:0016020"(membrane)|go:"GO:0031593"(polyubiquitin modification-dependent protein binding)|go:"GO:0034614"(cellular response to reactive oxygen species)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0046872"(metal ion binding)|go:"GO:0071944"(cell periphery)|interpro:IPR002110(Ankyrin)|interpro:IPR020683|interpro:IPR036770|interpro:IPR037278|interpro:IPR001164(Arf GTPase activating protein)|interpro:IPR038508|interpro:IPR027417|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR001806(Ras GTPase) intact:EBI-25507525(chain-parent) - - chain-seq-start:833|chain-seq-end:2837 figure legend:T1|comment:"The very large nsp3 was divided into three parts of approximately similar size (nsp3a, 3b, and 3c). In total, 15 MHV full-length proteins or isolated domains (including nsp3a and 3b) were used as bait to screen a mouse brain cDNA library."|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) - 2020/04/09 2020/04/13 rogid:nTpbCz1pAg/zOrnZ7CYFLrgOyc010090 rogid:/X+hmk/7yCyCykKykcDQ4x7OBSs11142 rigid:rvkmubqB4EAy7lGoICvnUowY3UE false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:P00397 uniprotkb:P0C6X9-PRO_0000037340 intact:EBI-25509231|ensembl:ENSMUSP00000080993 intact:EBI-25509188 psi-mi:cox1_mouse(display_long)|uniprotkb:Mtco1(gene name)|psi-mi:Mtco1(display_short)|uniprotkb:COI(gene name synonym)|uniprotkb:mt-Co1(gene name synonym)|uniprotkb:Cytochrome c oxidase polypeptide I(gene name synonym) psi-mi:p0c6x9-pro_0000037340(display_long)|uniprotkb:rep(gene name)|psi-mi:rep(display_short)|uniprotkb:ORF1ab polyprotein(gene name synonym)|uniprotkb:1a-1b(orf name) psi-mi:"MI:0398"(two hybrid pooling approach) Vidalain et al. (2014) imex:IM-27904|pubmed:25720483 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:11142(cvma5)|taxid:11142("Murine coronavirus (strain A59)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-25509264|imex:IM-27904-39 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSMUSG00000064351(gene)|ensembl:ENSMUST00000082402(transcript)|go:"GO:0004129"(cytochrome-c oxidase activity)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005750"(mitochondrial respiratory chain complex III)|go:"GO:0005751"(mitochondrial respiratory chain complex IV)|go:"GO:0006123"(mitochondrial electron transport, cytochrome c to oxygen)|go:"GO:0006979"(response to oxidative stress)|go:"GO:0007568"(aging)|go:"GO:0009060"(aerobic respiration)|go:"GO:0015990"(electron transport coupled proton transport)|go:"GO:0020037"(heme binding)|go:"GO:0021549"(cerebellum development)|go:"GO:0022904"(respiratory electron transport chain)|go:"GO:0045277"(respiratory chain complex IV)|go:"GO:0046688"(response to copper ion)|go:"GO:0046872"(metal ion binding)|go:"GO:0051602"(response to electrical stimulus)|interpro:IPR000883(Cytochrome c oxidase, subunit I)|interpro:IPR023615|interpro:IPR023616|interpro:IPR033944|interpro:IPR036927|reactome:R-MMU-5628897|reactome:R-MMU-611105|reactome:R-MMU-9707564|dip:DIP-61656N|refseq:NP_904330.1 intact:EBI-25507525(chain-parent) - - chain-seq-start:833|chain-seq-end:2837 figure legend:T1|comment:"The very large nsp3 was divided into three parts of approximately similar size (nsp3a, 3b, and 3c). In total, 15 MHV full-length proteins or isolated domains (including nsp3a and 3b) were used as bait to screen a mouse brain cDNA library."|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) - 2020/04/09 2020/04/13 rogid:S9pH5d5DgdYmV842FpXlycwFqt810090 rogid:/X+hmk/7yCyCykKykcDQ4x7OBSs11142 rigid:eosLl6Dso+EaRMHcft3cww7op4c false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:P10639 uniprotkb:P0C6X9-PRO_0000037340 intact:EBI-2310471|uniprotkb:Q52KC4|uniprotkb:Q9D8R0|ensembl:ENSMUSP00000030051 intact:EBI-25509188 psi-mi:thio_mouse(display_long)|uniprotkb:Txn(gene name)|psi-mi:Txn(display_short)|uniprotkb:Txn1(gene name synonym)|uniprotkb:ATL-derived factor(gene name synonym) psi-mi:p0c6x9-pro_0000037340(display_long)|uniprotkb:rep(gene name)|psi-mi:rep(display_short)|uniprotkb:ORF1ab polyprotein(gene name synonym)|uniprotkb:1a-1b(orf name) psi-mi:"MI:0398"(two hybrid pooling approach) Vidalain et al. (2014) imex:IM-27904|pubmed:25720483 taxid:10090(mouse)|taxid:10090(Mus musculus) taxid:11142(cvma5)|taxid:11142("Murine coronavirus (strain A59)") psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-25509269|imex:IM-27904-59 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_035790.1|ensembl:ENSMUSG00000028367(gene)|ensembl:ENSMUST00000030051(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0005576"(extracellular region)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0006662"(glycerol ether metabolic process)|go:"GO:0009314"(response to radiation)|go:"GO:0015035"(protein-disulfide reductase activity)|go:"GO:0019899"(enzyme binding)|go:"GO:0030424"(axon)|go:"GO:0030425"(dendrite)|go:"GO:0033138"(positive regulation of peptidyl-serine phosphorylation)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043388"(positive regulation of DNA binding)|go:"GO:0045454"(cell redox homeostasis)|go:"GO:0046826"(negative regulation of protein export from nucleus)|go:"GO:0047134"("protein-disulfide reductase (NAD(P)) activity")|go:"GO:0071731"(response to nitric oxide)|go:"GO:1903206"(negative regulation of hydrogen peroxide-induced cell death)|go:"GO:2000170"(positive regulation of peptidyl-cysteine S-nitrosylation)|interpro:IPR005746(Thioredoxin)|interpro:IPR013766(Thioredoxin domain)|interpro:IPR017937|interpro:IPR036249|mint:P10639|reactome:R-MMU-2559580|reactome:R-MMU-3299685|reactome:R-MMU-499943|reactome:R-MMU-5628897|reactome:R-MMU-5676934|reactome:R-MMU-844456 intact:EBI-25507525(chain-parent) - - chain-seq-start:833|chain-seq-end:2837 figure legend:T1|comment:"The very large nsp3 was divided into three parts of approximately similar size (nsp3a, 3b, and 3c). In total, 15 MHV full-length proteins or isolated domains (including nsp3a and 3b) were used as bait to screen a mouse brain cDNA library."|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:559292(yeast)|taxid:559292(Saccharomyces cerevisiae) - 2020/04/09 2020/04/13 rogid:iVrmQ/JC80E6coR3HmdurmcEbXo10090 rogid:/X+hmk/7yCyCykKykcDQ4x7OBSs11142 rigid:A29KJN1mu4uZ8d5dceqGCk4vKh8 false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification)