#ID(s) interactor A ID(s) interactor B Alt. ID(s) interactor A Alt. ID(s) interactor B Alias(es) interactor A Alias(es) interactor B Interaction detection method(s) Publication 1st author(s) Publication Identifier(s) Taxid interactor A Taxid interactor B Interaction type(s) Source database(s) Interaction identifier(s) Confidence value(s) Expansion method(s) Biological role(s) interactor A Biological role(s) interactor B Experimental role(s) interactor A Experimental role(s) interactor B Type(s) interactor A Type(s) interactor B Xref(s) interactor A Xref(s) interactor B Interaction Xref(s) Annotation(s) interactor A Annotation(s) interactor B Interaction annotation(s) Host organism(s) Interaction parameter(s) Creation date Update date Checksum(s) interactor A Checksum(s) interactor B Interaction Checksum(s) Negative Feature(s) interactor A Feature(s) interactor B Stoichiometry(s) interactor A Stoichiometry(s) interactor B Identification method participant A Identification method participant B uniprotkb:Q92508 uniprotkb:P04155 intact:EBI-10986212|intact:EBI-28972558|ensembl:ENSP00000301015|uniprotkb:A6NHT9|uniprotkb:Q0KKZ9|uniprotkb:A7E2B7 intact:EBI-743871|ensembl:ENSP00000291527 psi-mi:piez1_human(display_long)|uniprotkb:PIEZO1(gene name)|psi-mi:PIEZO1(display_short)|uniprotkb:FAM38A(gene name synonym)|uniprotkb:KIAA0233(gene name synonym)|uniprotkb:Membrane protein induced by beta-amyloid treatment(gene name synonym)|uniprotkb:Protein FAM38A(gene name synonym) psi-mi:tff1_human(display_long)|uniprotkb:Protein pS2(gene name synonym)|uniprotkb:Polypeptide P1.A(gene name synonym)|uniprotkb:Breast cancer estrogen-inducible protein(gene name synonym)|uniprotkb:PNR-2(gene name synonym)|uniprotkb:TFF1(gene name)|psi-mi:TFF1(display_short)|uniprotkb:BCEI(gene name synonym)|uniprotkb:PS2(gene name synonym) psi-mi:"MI:0018"(two hybrid) Yang et al. (2014) pubmed:24798994|imex:IM-28057 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-25640234|imex:IM-28057-1 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSP00000301015|refseq:NP_001136336.2|ensembl:ENSG00000103335(gene)|ensembl:ENST00000301015(transcript)|go:"GO:0005261"(cation channel activity)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005886"(plasma membrane)|go:"GO:0006812"(cation transport)|go:"GO:0008381"(mechanosensitive ion channel activity)|go:"GO:0010831"(positive regulation of myotube differentiation)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0031258"(lamellipodium membrane)|go:"GO:0033116"(endoplasmic reticulum-Golgi intermediate compartment membrane)|go:"GO:0033625"(positive regulation of integrin activation)|go:"GO:0033634"(positive regulation of cell-cell adhesion mediated by integrin)|go:"GO:0042391"(regulation of membrane potential)|go:"GO:0050982"(detection of mechanical stimulus)|go:"GO:0071260"(cellular response to mechanical stimulus)|interpro:IPR027272|interpro:IPR031334|interpro:IPR031805 refseq:NP_003216.1|ensembl:ENSG00000160182(gene)|ensembl:ENST00000291527(transcript)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0005975"(carbohydrate metabolic process)|go:"GO:0008083"(growth factor activity)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0010039"(response to iron ion)|go:"GO:0030154"(cell differentiation)|go:"GO:0030277"(maintenance of gastrointestinal epithelium)|go:"GO:0035902"(response to immobilization stress)|go:"GO:0043434"(response to peptide hormone)|interpro:IPR000519(P-type trefoil)|interpro:IPR017957|interpro:IPR017994|rcsb pdb:1HI7|rcsb pdb:1PS2|rcsb pdb:6V1D|reactome:R-HSA-9018519 - - - figure legend:no figure|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2020/06/05 2020/06/08 rogid:UKOxkX5fbLHiKEBKVSfHZN1Eu3s9606 rogid:AsrVoDgxWupA7lG87+LMvc23BWM9606 rigid:8K5mlXDwULO/IVHcw2xvU7l3DD4 false - - - - psi-mi:"MI:0078"(nucleotide sequence identification) psi-mi:"MI:0078"(nucleotide sequence identification) uniprotkb:Q92508 uniprotkb:P04155 intact:EBI-10986212|intact:EBI-28972558|ensembl:ENSP00000301015|uniprotkb:A6NHT9|uniprotkb:Q0KKZ9|uniprotkb:A7E2B7 intact:EBI-743871|ensembl:ENSP00000291527 psi-mi:piez1_human(display_long)|uniprotkb:PIEZO1(gene name)|psi-mi:PIEZO1(display_short)|uniprotkb:FAM38A(gene name synonym)|uniprotkb:KIAA0233(gene name synonym)|uniprotkb:Membrane protein induced by beta-amyloid treatment(gene name synonym)|uniprotkb:Protein FAM38A(gene name synonym) psi-mi:tff1_human(display_long)|uniprotkb:Protein pS2(gene name synonym)|uniprotkb:Polypeptide P1.A(gene name synonym)|uniprotkb:Breast cancer estrogen-inducible protein(gene name synonym)|uniprotkb:PNR-2(gene name synonym)|uniprotkb:TFF1(gene name)|psi-mi:TFF1(display_short)|uniprotkb:BCEI(gene name synonym)|uniprotkb:PS2(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Yang et al. (2014) pubmed:24798994|imex:IM-28057 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-25640253|imex:IM-28057-3 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSP00000301015|refseq:NP_001136336.2|ensembl:ENSG00000103335(gene)|ensembl:ENST00000301015(transcript)|go:"GO:0005261"(cation channel activity)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005886"(plasma membrane)|go:"GO:0006812"(cation transport)|go:"GO:0008381"(mechanosensitive ion channel activity)|go:"GO:0010831"(positive regulation of myotube differentiation)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0031258"(lamellipodium membrane)|go:"GO:0033116"(endoplasmic reticulum-Golgi intermediate compartment membrane)|go:"GO:0033625"(positive regulation of integrin activation)|go:"GO:0033634"(positive regulation of cell-cell adhesion mediated by integrin)|go:"GO:0042391"(regulation of membrane potential)|go:"GO:0050982"(detection of mechanical stimulus)|go:"GO:0071260"(cellular response to mechanical stimulus)|interpro:IPR027272|interpro:IPR031334|interpro:IPR031805 refseq:NP_003216.1|ensembl:ENSG00000160182(gene)|ensembl:ENST00000291527(transcript)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0005975"(carbohydrate metabolic process)|go:"GO:0008083"(growth factor activity)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0010039"(response to iron ion)|go:"GO:0030154"(cell differentiation)|go:"GO:0030277"(maintenance of gastrointestinal epithelium)|go:"GO:0035902"(response to immobilization stress)|go:"GO:0043434"(response to peptide hormone)|interpro:IPR000519(P-type trefoil)|interpro:IPR017957|interpro:IPR017994|rcsb pdb:1HI7|rcsb pdb:1PS2|rcsb pdb:6V1D|reactome:R-HSA-9018519 - - - figure legend:1A|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-ges1)|taxid:9606(immortalized human gastric epithelial cell line) - 2020/06/05 2020/06/08 rogid:UKOxkX5fbLHiKEBKVSfHZN1Eu3s9606 rogid:AsrVoDgxWupA7lG87+LMvc23BWM9606 rigid:8K5mlXDwULO/IVHcw2xvU7l3DD4 false - - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:Q92508 uniprotkb:P04155 intact:EBI-10986212|intact:EBI-28972558|ensembl:ENSP00000301015|uniprotkb:A6NHT9|uniprotkb:Q0KKZ9|uniprotkb:A7E2B7 intact:EBI-743871|ensembl:ENSP00000291527 psi-mi:piez1_human(display_long)|uniprotkb:PIEZO1(gene name)|psi-mi:PIEZO1(display_short)|uniprotkb:FAM38A(gene name synonym)|uniprotkb:KIAA0233(gene name synonym)|uniprotkb:Membrane protein induced by beta-amyloid treatment(gene name synonym)|uniprotkb:Protein FAM38A(gene name synonym) psi-mi:tff1_human(display_long)|uniprotkb:Protein pS2(gene name synonym)|uniprotkb:Polypeptide P1.A(gene name synonym)|uniprotkb:Breast cancer estrogen-inducible protein(gene name synonym)|uniprotkb:PNR-2(gene name synonym)|uniprotkb:TFF1(gene name)|psi-mi:TFF1(display_short)|uniprotkb:BCEI(gene name synonym)|uniprotkb:PS2(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Yang et al. (2014) pubmed:24798994|imex:IM-28057 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-25640269|imex:IM-28057-5 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSP00000301015|refseq:NP_001136336.2|ensembl:ENSG00000103335(gene)|ensembl:ENST00000301015(transcript)|go:"GO:0005261"(cation channel activity)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005886"(plasma membrane)|go:"GO:0006812"(cation transport)|go:"GO:0008381"(mechanosensitive ion channel activity)|go:"GO:0010831"(positive regulation of myotube differentiation)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0031258"(lamellipodium membrane)|go:"GO:0033116"(endoplasmic reticulum-Golgi intermediate compartment membrane)|go:"GO:0033625"(positive regulation of integrin activation)|go:"GO:0033634"(positive regulation of cell-cell adhesion mediated by integrin)|go:"GO:0042391"(regulation of membrane potential)|go:"GO:0050982"(detection of mechanical stimulus)|go:"GO:0071260"(cellular response to mechanical stimulus)|interpro:IPR027272|interpro:IPR031334|interpro:IPR031805 refseq:NP_003216.1|ensembl:ENSG00000160182(gene)|ensembl:ENST00000291527(transcript)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0005975"(carbohydrate metabolic process)|go:"GO:0008083"(growth factor activity)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0010039"(response to iron ion)|go:"GO:0030154"(cell differentiation)|go:"GO:0030277"(maintenance of gastrointestinal epithelium)|go:"GO:0035902"(response to immobilization stress)|go:"GO:0043434"(response to peptide hormone)|interpro:IPR000519(P-type trefoil)|interpro:IPR017957|interpro:IPR017994|rcsb pdb:1HI7|rcsb pdb:1PS2|rcsb pdb:6V1D|reactome:R-HSA-9018519 - - - figure legend:1B|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-ges1)|taxid:9606(immortalized human gastric epithelial cell line) - 2020/06/05 2020/06/08 rogid:UKOxkX5fbLHiKEBKVSfHZN1Eu3s9606 rogid:AsrVoDgxWupA7lG87+LMvc23BWM9606 rigid:8K5mlXDwULO/IVHcw2xvU7l3DD4 false - ha tag:?-? - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:Q92508 uniprotkb:P04155 intact:EBI-10986212|intact:EBI-28972558|ensembl:ENSP00000301015|uniprotkb:A6NHT9|uniprotkb:Q0KKZ9|uniprotkb:A7E2B7 intact:EBI-743871|ensembl:ENSP00000291527 psi-mi:piez1_human(display_long)|uniprotkb:PIEZO1(gene name)|psi-mi:PIEZO1(display_short)|uniprotkb:FAM38A(gene name synonym)|uniprotkb:KIAA0233(gene name synonym)|uniprotkb:Membrane protein induced by beta-amyloid treatment(gene name synonym)|uniprotkb:Protein FAM38A(gene name synonym) psi-mi:tff1_human(display_long)|uniprotkb:Protein pS2(gene name synonym)|uniprotkb:Polypeptide P1.A(gene name synonym)|uniprotkb:Breast cancer estrogen-inducible protein(gene name synonym)|uniprotkb:PNR-2(gene name synonym)|uniprotkb:TFF1(gene name)|psi-mi:TFF1(display_short)|uniprotkb:BCEI(gene name synonym)|uniprotkb:PS2(gene name synonym) psi-mi:"MI:0663"(confocal microscopy) Yang et al. (2014) pubmed:24798994|imex:IM-28057 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0403"(colocalization) psi-mi:"MI:0469"(IntAct) intact:EBI-25640282|imex:IM-28057-7 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSP00000301015|refseq:NP_001136336.2|ensembl:ENSG00000103335(gene)|ensembl:ENST00000301015(transcript)|go:"GO:0005261"(cation channel activity)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005886"(plasma membrane)|go:"GO:0006812"(cation transport)|go:"GO:0008381"(mechanosensitive ion channel activity)|go:"GO:0010831"(positive regulation of myotube differentiation)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0031258"(lamellipodium membrane)|go:"GO:0033116"(endoplasmic reticulum-Golgi intermediate compartment membrane)|go:"GO:0033625"(positive regulation of integrin activation)|go:"GO:0033634"(positive regulation of cell-cell adhesion mediated by integrin)|go:"GO:0042391"(regulation of membrane potential)|go:"GO:0050982"(detection of mechanical stimulus)|go:"GO:0071260"(cellular response to mechanical stimulus)|interpro:IPR027272|interpro:IPR031334|interpro:IPR031805 refseq:NP_003216.1|ensembl:ENSG00000160182(gene)|ensembl:ENST00000291527(transcript)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0005975"(carbohydrate metabolic process)|go:"GO:0008083"(growth factor activity)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0010039"(response to iron ion)|go:"GO:0030154"(cell differentiation)|go:"GO:0030277"(maintenance of gastrointestinal epithelium)|go:"GO:0035902"(response to immobilization stress)|go:"GO:0043434"(response to peptide hormone)|interpro:IPR000519(P-type trefoil)|interpro:IPR017957|interpro:IPR017994|rcsb pdb:1HI7|rcsb pdb:1PS2|rcsb pdb:6V1D|reactome:R-HSA-9018519 go:"GO:0005737"(cytoplasm) - - figure legend:1C|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-ges1)|taxid:9606(immortalized human gastric epithelial cell line) - 2020/06/05 2020/06/08 rogid:UKOxkX5fbLHiKEBKVSfHZN1Eu3s9606 rogid:AsrVoDgxWupA7lG87+LMvc23BWM9606 rigid:8K5mlXDwULO/IVHcw2xvU7l3DD4 false - ha tag:?-? - - psi-mi:"MI:1200"(immunocytochemistry) psi-mi:"MI:1200"(immunocytochemistry) uniprotkb:Q92508 uniprotkb:P04155 intact:EBI-10986212|intact:EBI-28972558|ensembl:ENSP00000301015|uniprotkb:A6NHT9|uniprotkb:Q0KKZ9|uniprotkb:A7E2B7 intact:EBI-743871|ensembl:ENSP00000291527 psi-mi:piez1_human(display_long)|uniprotkb:PIEZO1(gene name)|psi-mi:PIEZO1(display_short)|uniprotkb:FAM38A(gene name synonym)|uniprotkb:KIAA0233(gene name synonym)|uniprotkb:Membrane protein induced by beta-amyloid treatment(gene name synonym)|uniprotkb:Protein FAM38A(gene name synonym) psi-mi:tff1_human(display_long)|uniprotkb:Protein pS2(gene name synonym)|uniprotkb:Polypeptide P1.A(gene name synonym)|uniprotkb:Breast cancer estrogen-inducible protein(gene name synonym)|uniprotkb:PNR-2(gene name synonym)|uniprotkb:TFF1(gene name)|psi-mi:TFF1(display_short)|uniprotkb:BCEI(gene name synonym)|uniprotkb:PS2(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Yang et al. (2014) pubmed:24798994|imex:IM-28057 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0469"(IntAct) intact:EBI-25640305|imex:IM-28057-9 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSP00000301015|refseq:NP_001136336.2|ensembl:ENSG00000103335(gene)|ensembl:ENST00000301015(transcript)|go:"GO:0005261"(cation channel activity)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005886"(plasma membrane)|go:"GO:0006812"(cation transport)|go:"GO:0008381"(mechanosensitive ion channel activity)|go:"GO:0010831"(positive regulation of myotube differentiation)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0031258"(lamellipodium membrane)|go:"GO:0033116"(endoplasmic reticulum-Golgi intermediate compartment membrane)|go:"GO:0033625"(positive regulation of integrin activation)|go:"GO:0033634"(positive regulation of cell-cell adhesion mediated by integrin)|go:"GO:0042391"(regulation of membrane potential)|go:"GO:0050982"(detection of mechanical stimulus)|go:"GO:0071260"(cellular response to mechanical stimulus)|interpro:IPR027272|interpro:IPR031334|interpro:IPR031805 refseq:NP_003216.1|ensembl:ENSG00000160182(gene)|ensembl:ENST00000291527(transcript)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0005975"(carbohydrate metabolic process)|go:"GO:0008083"(growth factor activity)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0010039"(response to iron ion)|go:"GO:0030154"(cell differentiation)|go:"GO:0030277"(maintenance of gastrointestinal epithelium)|go:"GO:0035902"(response to immobilization stress)|go:"GO:0043434"(response to peptide hormone)|interpro:IPR000519(P-type trefoil)|interpro:IPR017957|interpro:IPR017994|rcsb pdb:1HI7|rcsb pdb:1PS2|rcsb pdb:6V1D|reactome:R-HSA-9018519 - - - figure legend:2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/06/05 2020/06/08 rogid:UKOxkX5fbLHiKEBKVSfHZN1Eu3s9606 rogid:AsrVoDgxWupA7lG87+LMvc23BWM9606 rigid:8K5mlXDwULO/IVHcw2xvU7l3DD4 false sufficient binding region:1985..1985-2521..2521|myc tag:?-? ha tag:?-? - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot)