#ID(s) interactor A	ID(s) interactor B	Alt. ID(s) interactor A	Alt. ID(s) interactor B	Alias(es) interactor A	Alias(es) interactor B	Interaction detection method(s)	Publication 1st author(s)	Publication Identifier(s)	Taxid interactor A	Taxid interactor B	Interaction type(s)	Source database(s)	Interaction identifier(s)	Confidence value(s)	Expansion method(s)	Biological role(s) interactor A	Biological role(s) interactor B	Experimental role(s) interactor A	Experimental role(s) interactor B	Type(s) interactor A	Type(s) interactor B	Xref(s) interactor A	Xref(s) interactor B	Interaction Xref(s)	Annotation(s) interactor A	Annotation(s) interactor B	Interaction annotation(s)	Host organism(s)	Interaction parameter(s)	Creation date	Update date	Checksum(s) interactor A	Checksum(s) interactor B	Interaction Checksum(s)	Negative	Feature(s) interactor A	Feature(s) interactor B	Stoichiometry(s) interactor A	Stoichiometry(s) interactor B	Identification method participant A	Identification method participant B
uniprotkb:Q5T4F4	uniprotkb:Q6DD88	intact:EBI-3892947|uniprotkb:Q5T4F1|uniprotkb:Q5T4F2|uniprotkb:Q5T4F3|uniprotkb:Q8N1K0|uniprotkb:Q8N6D6|uniprotkb:Q8NCA0|uniprotkb:Q8NDE4|uniprotkb:Q96M08|uniprotkb:B7Z404|uniprotkb:G8JLC3|uniprotkb:B7Z3S0|uniprotkb:B7Z626|uniprotkb:G8JLF0|uniprotkb:J3KP98|ensembl:ENSP00000377282|ensembl:ENSP00000506975	intact:EBI-6165882|ensembl:ENSP00000381844|uniprotkb:Q8N7W5|uniprotkb:Q9H8Q5|uniprotkb:Q9UFL1	psi-mi:zfy27_human(display_long)|uniprotkb:Spastic paraplegia 33 protein(gene name synonym)|uniprotkb:SPG33(gene name synonym)|uniprotkb:Zinc finger FYVE domain-containing protein 27(gene name synonym)|uniprotkb:ZFYVE27(gene name)|psi-mi:ZFYVE27(display_short)	psi-mi:atla3_human(display_long)|uniprotkb:ATL3(gene name)|psi-mi:ATL3(display_short)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Chang et al. (2013)	pubmed:23969831|imex:IM-27887	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0486"(UniProt)	intact:EBI-25506308|imex:IM-27887-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001002261.1|refseq:NP_001002262.1|refseq:NP_001167590.1|refseq:NP_001167591.1|refseq:NP_001167593.1|refseq:NP_653189.3|dip:DIP-61530N|refseq:XP_005269559.1|refseq:XP_005269560.1|refseq:XP_005269561.1|refseq:XP_005269563.1|refseq:NP_001167592.1|go:"GO:0016192"(vesicle-mediated transport)|ensembl:ENSG00000155256(gene)|ensembl:ENST00000393677(transcript)|go:"GO:0030176"(integral component of endoplasmic reticulum membrane)|ensembl:ENST00000684270(transcript)|go:"GO:0030424"(axon)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0030425"(dendrite)|go:"GO:0031175"(neuron projection development)|go:"GO:0032584"(growth cone membrane)|go:"GO:0005829"(cytosol)|go:"GO:0042802"(identical protein binding)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0043621"(protein self-association)|go:"GO:0045773"(positive regulation of axon extension)|go:"GO:0046872"(metal ion binding)|go:"GO:0048011"(neurotrophin TRK receptor signaling pathway)|go:"GO:0055038"(recycling endosome membrane)|go:"GO:0071782"(endoplasmic reticulum tubular network)|go:"GO:0071787"(endoplasmic reticulum tubular network formation)|go:"GO:0072659"(protein localization to plasma membrane)|interpro:IPR000306(Zinc finger, FYVE-type)|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017455(Zinc finger, FYVE-related)|interpro:IPR042405|rcsb pdb:1X4U	go:"GO:0007029"(endoplasmic reticulum organization)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0051260"(protein homooligomerization)|go:"GO:0071782"(endoplasmic reticulum tubular network)|go:"GO:0098826"(endoplasmic reticulum tubular network membrane)|go:"GO:1903373"(positive regulation of endoplasmic reticulum tubular network organization)|interpro:IPR003191(Guanylate-binding protein, C-terminal)|interpro:IPR015894(Guanylate-binding protein, N-terminal)|interpro:IPR027417|interpro:IPR030386|interpro:IPR036543|mint:Q6DD88|rcsb pdb:5VGR|rcsb pdb:6XJO|go:"GO:0007030"(Golgi organization)|ensembl:ENSG00000184743(gene)|ensembl:ENST00000398868(transcript)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005783"(endoplasmic reticulum)|refseq:NP_001276977.1|refseq:NP_056274.3	-	-	-	figure legend:Fig. 2F|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2020/04/08	2020/04/08	rogid:4ZValZeuAPt2j1inKYjoMDdC+EI9606	rogid:9vgpZvUg5aFAZyNiZ2pdEPn/J7o9606	rigid:xsdwDeH+aFIGKcuYhq3y8CyGyJw	false	-	-	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:Q5T4F4	uniprotkb:Q00765	intact:EBI-3892947|uniprotkb:Q5T4F1|uniprotkb:Q5T4F2|uniprotkb:Q5T4F3|uniprotkb:Q8N1K0|uniprotkb:Q8N6D6|uniprotkb:Q8NCA0|uniprotkb:Q8NDE4|uniprotkb:Q96M08|uniprotkb:B7Z404|uniprotkb:G8JLC3|uniprotkb:B7Z3S0|uniprotkb:B7Z626|uniprotkb:G8JLF0|uniprotkb:J3KP98|ensembl:ENSP00000377282|ensembl:ENSP00000506975	intact:EBI-1549827|uniprotkb:Q04198|uniprotkb:Q5QGT0|uniprotkb:Q9BWH9|uniprotkb:D3DT04|uniprotkb:B7Z681|ensembl:ENSP00000368959	psi-mi:zfy27_human(display_long)|uniprotkb:Spastic paraplegia 33 protein(gene name synonym)|uniprotkb:SPG33(gene name synonym)|uniprotkb:Zinc finger FYVE domain-containing protein 27(gene name synonym)|uniprotkb:ZFYVE27(gene name)|psi-mi:ZFYVE27(display_short)	psi-mi:reep5_human(display_long)|uniprotkb:REEP5(gene name)|psi-mi:REEP5(display_short)|uniprotkb:C5orf18(gene name synonym)|uniprotkb:DP1(gene name synonym)|uniprotkb:TB2(gene name synonym)|uniprotkb:Polyposis locus protein 1(gene name synonym)|uniprotkb:Protein TB2(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Chang et al. (2013)	pubmed:23969831|imex:IM-27887	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0486"(UniProt)	intact:EBI-25506308|imex:IM-27887-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001002261.1|refseq:NP_001002262.1|refseq:NP_001167590.1|refseq:NP_001167591.1|refseq:NP_001167593.1|refseq:NP_653189.3|dip:DIP-61530N|refseq:XP_005269559.1|refseq:XP_005269560.1|refseq:XP_005269561.1|refseq:XP_005269563.1|refseq:NP_001167592.1|go:"GO:0016192"(vesicle-mediated transport)|ensembl:ENSG00000155256(gene)|ensembl:ENST00000393677(transcript)|go:"GO:0030176"(integral component of endoplasmic reticulum membrane)|ensembl:ENST00000684270(transcript)|go:"GO:0030424"(axon)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0030425"(dendrite)|go:"GO:0031175"(neuron projection development)|go:"GO:0032584"(growth cone membrane)|go:"GO:0005829"(cytosol)|go:"GO:0042802"(identical protein binding)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0043621"(protein self-association)|go:"GO:0045773"(positive regulation of axon extension)|go:"GO:0046872"(metal ion binding)|go:"GO:0048011"(neurotrophin TRK receptor signaling pathway)|go:"GO:0055038"(recycling endosome membrane)|go:"GO:0071782"(endoplasmic reticulum tubular network)|go:"GO:0071787"(endoplasmic reticulum tubular network formation)|go:"GO:0072659"(protein localization to plasma membrane)|interpro:IPR000306(Zinc finger, FYVE-type)|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017455(Zinc finger, FYVE-related)|interpro:IPR042405|rcsb pdb:1X4U	refseq:NP_005660.4|ensembl:ENSG00000129625(gene)|ensembl:ENST00000379638(transcript)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0007029"(endoplasmic reticulum organization)|go:"GO:0016021"(integral component of membrane)|go:"GO:0032386"(regulation of intracellular transport)|go:"GO:0071782"(endoplasmic reticulum tubular network)|interpro:IPR004345(TB2/DP1 and HVA22 related protein)|reactome:R-HSA-381753	-	-	-	figure legend:Fig. 2F|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2020/04/08	2020/04/08	rogid:4ZValZeuAPt2j1inKYjoMDdC+EI9606	rogid:Z6Lzi37F0AfHZBnHri7k4EUpSRQ9606	rigid:xsdwDeH+aFIGKcuYhq3y8CyGyJw	false	-	-	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:Q5T4F4	uniprotkb:Q8NHH9	intact:EBI-3892947|uniprotkb:Q5T4F1|uniprotkb:Q5T4F2|uniprotkb:Q5T4F3|uniprotkb:Q8N1K0|uniprotkb:Q8N6D6|uniprotkb:Q8NCA0|uniprotkb:Q8NDE4|uniprotkb:Q96M08|uniprotkb:B7Z404|uniprotkb:G8JLC3|uniprotkb:B7Z3S0|uniprotkb:B7Z626|uniprotkb:G8JLF0|uniprotkb:J3KP98|ensembl:ENSP00000377282|ensembl:ENSP00000506975	intact:EBI-2410430|uniprotkb:B7Z1X2|ensembl:ENSP00000368237|uniprotkb:Q4ZG30|uniprotkb:Q7Z630|uniprotkb:Q8NHH8|uniprotkb:Q9H5M7|intact:EBI-2559696|uniprotkb:B7Z7X8|intact:EBI-11081412	psi-mi:zfy27_human(display_long)|uniprotkb:Spastic paraplegia 33 protein(gene name synonym)|uniprotkb:SPG33(gene name synonym)|uniprotkb:Zinc finger FYVE domain-containing protein 27(gene name synonym)|uniprotkb:ZFYVE27(gene name)|psi-mi:ZFYVE27(display_short)	psi-mi:atla2_human(display_long)|uniprotkb:ATL2(gene name)|psi-mi:ATL2(display_short)|uniprotkb:ARL6IP2(gene name synonym)|uniprotkb:ADP-ribosylation factor-like protein 6-interacting protein 2(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Chang et al. (2013)	pubmed:23969831|imex:IM-27887	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0486"(UniProt)	intact:EBI-25506308|imex:IM-27887-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001002261.1|refseq:NP_001002262.1|refseq:NP_001167590.1|refseq:NP_001167591.1|refseq:NP_001167593.1|refseq:NP_653189.3|dip:DIP-61530N|refseq:XP_005269559.1|refseq:XP_005269560.1|refseq:XP_005269561.1|refseq:XP_005269563.1|refseq:NP_001167592.1|go:"GO:0016192"(vesicle-mediated transport)|ensembl:ENSG00000155256(gene)|ensembl:ENST00000393677(transcript)|go:"GO:0030176"(integral component of endoplasmic reticulum membrane)|ensembl:ENST00000684270(transcript)|go:"GO:0030424"(axon)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0030425"(dendrite)|go:"GO:0031175"(neuron projection development)|go:"GO:0032584"(growth cone membrane)|go:"GO:0005829"(cytosol)|go:"GO:0042802"(identical protein binding)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0043621"(protein self-association)|go:"GO:0045773"(positive regulation of axon extension)|go:"GO:0046872"(metal ion binding)|go:"GO:0048011"(neurotrophin TRK receptor signaling pathway)|go:"GO:0055038"(recycling endosome membrane)|go:"GO:0071782"(endoplasmic reticulum tubular network)|go:"GO:0071787"(endoplasmic reticulum tubular network formation)|go:"GO:0072659"(protein localization to plasma membrane)|interpro:IPR000306(Zinc finger, FYVE-type)|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017455(Zinc finger, FYVE-related)|interpro:IPR042405|rcsb pdb:1X4U	ensembl:ENSG00000119787(gene)|ensembl:ENST00000378954(transcript)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0007029"(endoplasmic reticulum organization)|go:"GO:0007030"(Golgi organization)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0051260"(protein homooligomerization)|go:"GO:0098826"(endoplasmic reticulum tubular network membrane)|go:"GO:1990809"(endoplasmic reticulum tubular network membrane organization)|interpro:IPR003191(Guanylate-binding protein, C-terminal)|interpro:IPR015894(Guanylate-binding protein, N-terminal)|interpro:IPR027417|interpro:IPR030386|interpro:IPR036543|mint:Q8NHH9|refseq:NP_001295005.1|refseq:NP_001129145.1|refseq:NP_071769.2|refseq:NP_001317387.1|refseq:NP_001317388.1|refseq:NP_001317389.1	-	-	-	figure legend:Fig. 2F|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2020/04/08	2020/04/08	rogid:4ZValZeuAPt2j1inKYjoMDdC+EI9606	rogid:MGye5g/TWQQv39oFMuhF+PUZcRM9606	rigid:xsdwDeH+aFIGKcuYhq3y8CyGyJw	false	-	-	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:Q5T4F4	uniprotkb:Q8WXF7	intact:EBI-3892947|uniprotkb:Q5T4F1|uniprotkb:Q5T4F2|uniprotkb:Q5T4F3|uniprotkb:Q8N1K0|uniprotkb:Q8N6D6|uniprotkb:Q8NCA0|uniprotkb:Q8NDE4|uniprotkb:Q96M08|uniprotkb:B7Z404|uniprotkb:G8JLC3|uniprotkb:B7Z3S0|uniprotkb:B7Z626|uniprotkb:G8JLF0|uniprotkb:J3KP98|ensembl:ENSP00000377282|ensembl:ENSP00000506975	intact:EBI-2410266|uniprotkb:A6NND5|uniprotkb:O95890|uniprotkb:Q96FK0|uniprotkb:A8K2C0|uniprotkb:G5E9T1|uniprotkb:Q69YH7|ensembl:ENSP00000351155	psi-mi:zfy27_human(display_long)|uniprotkb:Spastic paraplegia 33 protein(gene name synonym)|uniprotkb:SPG33(gene name synonym)|uniprotkb:Zinc finger FYVE domain-containing protein 27(gene name synonym)|uniprotkb:ZFYVE27(gene name)|psi-mi:ZFYVE27(display_short)	psi-mi:atla1_human(display_long)|uniprotkb:ATL1(gene name)|psi-mi:ATL1(display_short)|uniprotkb:GBP3(gene name synonym)|uniprotkb:SPG3A(gene name synonym)|uniprotkb:Spastic paraplegia 3 protein A(gene name synonym)|uniprotkb:Guanine nucleotide-binding protein 3(gene name synonym)|uniprotkb:GTP-binding protein 3(gene name synonym)|uniprotkb:Brain-specific GTP-binding protein(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Chang et al. (2013)	pubmed:23969831|imex:IM-27887	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0486"(UniProt)	intact:EBI-25506308|imex:IM-27887-1	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001002261.1|refseq:NP_001002262.1|refseq:NP_001167590.1|refseq:NP_001167591.1|refseq:NP_001167593.1|refseq:NP_653189.3|dip:DIP-61530N|refseq:XP_005269559.1|refseq:XP_005269560.1|refseq:XP_005269561.1|refseq:XP_005269563.1|refseq:NP_001167592.1|go:"GO:0016192"(vesicle-mediated transport)|ensembl:ENSG00000155256(gene)|ensembl:ENST00000393677(transcript)|go:"GO:0030176"(integral component of endoplasmic reticulum membrane)|ensembl:ENST00000684270(transcript)|go:"GO:0030424"(axon)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0030425"(dendrite)|go:"GO:0031175"(neuron projection development)|go:"GO:0032584"(growth cone membrane)|go:"GO:0005829"(cytosol)|go:"GO:0042802"(identical protein binding)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0043621"(protein self-association)|go:"GO:0045773"(positive regulation of axon extension)|go:"GO:0046872"(metal ion binding)|go:"GO:0048011"(neurotrophin TRK receptor signaling pathway)|go:"GO:0055038"(recycling endosome membrane)|go:"GO:0071782"(endoplasmic reticulum tubular network)|go:"GO:0071787"(endoplasmic reticulum tubular network formation)|go:"GO:0072659"(protein localization to plasma membrane)|interpro:IPR000306(Zinc finger, FYVE-type)|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017455(Zinc finger, FYVE-related)|interpro:IPR042405|rcsb pdb:1X4U	refseq:NP_001121185.1|refseq:NP_056999.2|refseq:NP_853629.2|dip:DIP-53502N|ensembl:ENSG00000198513(gene)|ensembl:ENST00000358385(transcript)|go:"GO:0000137"(Golgi cis cisterna)|go:"GO:0000139"(Golgi membrane)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0007029"(endoplasmic reticulum organization)|go:"GO:0007409"(axonogenesis)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030424"(axon)|go:"GO:0042802"(identical protein binding)|go:"GO:0051260"(protein homooligomerization)|go:"GO:0071782"(endoplasmic reticulum tubular network)|go:"GO:0098826"(endoplasmic reticulum tubular network membrane)|go:"GO:1990809"(endoplasmic reticulum tubular network membrane organization)|interpro:IPR015894(Guanylate-binding protein, N-terminal)|interpro:IPR027417|interpro:IPR030386|interpro:IPR036543|mint:Q8WXF7|rcsb pdb:3Q5D|rcsb pdb:3Q5E|rcsb pdb:3QNU|rcsb pdb:3QOF|rcsb pdb:4IDN|rcsb pdb:4IDO|rcsb pdb:4IDP|rcsb pdb:4IDQ|rcsb pdb:6B9D|rcsb pdb:6B9E|rcsb pdb:6B9F|rcsb pdb:6B9G|rcsb pdb:6XJN	-	-	-	figure legend:Fig. 2F|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2020/04/08	2020/04/08	rogid:4ZValZeuAPt2j1inKYjoMDdC+EI9606	rogid:xHgqrEBVA57vg40bCwdpIrhaWIw9606	rigid:xsdwDeH+aFIGKcuYhq3y8CyGyJw	false	-	-	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:Q5T4F4	uniprotkb:Q5T4F4	intact:EBI-3892947|uniprotkb:Q5T4F1|uniprotkb:Q5T4F2|uniprotkb:Q5T4F3|uniprotkb:Q8N1K0|uniprotkb:Q8N6D6|uniprotkb:Q8NCA0|uniprotkb:Q8NDE4|uniprotkb:Q96M08|uniprotkb:B7Z404|uniprotkb:G8JLC3|uniprotkb:B7Z3S0|uniprotkb:B7Z626|uniprotkb:G8JLF0|uniprotkb:J3KP98|ensembl:ENSP00000377282|ensembl:ENSP00000506975	intact:EBI-3892947|uniprotkb:Q5T4F1|uniprotkb:Q5T4F2|uniprotkb:Q5T4F3|uniprotkb:Q8N1K0|uniprotkb:Q8N6D6|uniprotkb:Q8NCA0|uniprotkb:Q8NDE4|uniprotkb:Q96M08|uniprotkb:B7Z404|uniprotkb:G8JLC3|uniprotkb:B7Z3S0|uniprotkb:B7Z626|uniprotkb:G8JLF0|uniprotkb:J3KP98|ensembl:ENSP00000377282|ensembl:ENSP00000506975	psi-mi:zfy27_human(display_long)|uniprotkb:Spastic paraplegia 33 protein(gene name synonym)|uniprotkb:SPG33(gene name synonym)|uniprotkb:Zinc finger FYVE domain-containing protein 27(gene name synonym)|uniprotkb:ZFYVE27(gene name)|psi-mi:ZFYVE27(display_short)	psi-mi:zfy27_human(display_long)|uniprotkb:Spastic paraplegia 33 protein(gene name synonym)|uniprotkb:SPG33(gene name synonym)|uniprotkb:Zinc finger FYVE domain-containing protein 27(gene name synonym)|uniprotkb:ZFYVE27(gene name)|psi-mi:ZFYVE27(display_short)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Chang et al. (2013)	pubmed:23969831|imex:IM-27887	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0486"(UniProt)	intact:EBI-25506327|imex:IM-27887-21	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001002261.1|refseq:NP_001002262.1|refseq:NP_001167590.1|refseq:NP_001167591.1|refseq:NP_001167593.1|refseq:NP_653189.3|dip:DIP-61530N|refseq:XP_005269559.1|refseq:XP_005269560.1|refseq:XP_005269561.1|refseq:XP_005269563.1|refseq:NP_001167592.1|go:"GO:0016192"(vesicle-mediated transport)|ensembl:ENSG00000155256(gene)|ensembl:ENST00000393677(transcript)|go:"GO:0030176"(integral component of endoplasmic reticulum membrane)|ensembl:ENST00000684270(transcript)|go:"GO:0030424"(axon)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0030425"(dendrite)|go:"GO:0031175"(neuron projection development)|go:"GO:0032584"(growth cone membrane)|go:"GO:0005829"(cytosol)|go:"GO:0042802"(identical protein binding)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0043621"(protein self-association)|go:"GO:0045773"(positive regulation of axon extension)|go:"GO:0046872"(metal ion binding)|go:"GO:0048011"(neurotrophin TRK receptor signaling pathway)|go:"GO:0055038"(recycling endosome membrane)|go:"GO:0071782"(endoplasmic reticulum tubular network)|go:"GO:0071787"(endoplasmic reticulum tubular network formation)|go:"GO:0072659"(protein localization to plasma membrane)|interpro:IPR000306(Zinc finger, FYVE-type)|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017455(Zinc finger, FYVE-related)|interpro:IPR042405|rcsb pdb:1X4U	refseq:NP_001002261.1|refseq:NP_001002262.1|refseq:NP_001167590.1|refseq:NP_001167591.1|refseq:NP_001167593.1|refseq:NP_653189.3|dip:DIP-61530N|refseq:XP_005269559.1|refseq:XP_005269560.1|refseq:XP_005269561.1|refseq:XP_005269563.1|refseq:NP_001167592.1|go:"GO:0016192"(vesicle-mediated transport)|ensembl:ENSG00000155256(gene)|ensembl:ENST00000393677(transcript)|go:"GO:0030176"(integral component of endoplasmic reticulum membrane)|ensembl:ENST00000684270(transcript)|go:"GO:0030424"(axon)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0030425"(dendrite)|go:"GO:0031175"(neuron projection development)|go:"GO:0032584"(growth cone membrane)|go:"GO:0005829"(cytosol)|go:"GO:0042802"(identical protein binding)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0043621"(protein self-association)|go:"GO:0045773"(positive regulation of axon extension)|go:"GO:0046872"(metal ion binding)|go:"GO:0048011"(neurotrophin TRK receptor signaling pathway)|go:"GO:0055038"(recycling endosome membrane)|go:"GO:0071782"(endoplasmic reticulum tubular network)|go:"GO:0071787"(endoplasmic reticulum tubular network formation)|go:"GO:0072659"(protein localization to plasma membrane)|interpro:IPR000306(Zinc finger, FYVE-type)|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017455(Zinc finger, FYVE-related)|interpro:IPR042405|rcsb pdb:1X4U	-	-	-	figure legend:Supp Fig. 1B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2020/04/08	2020/04/08	rogid:4ZValZeuAPt2j1inKYjoMDdC+EI9606	rogid:4ZValZeuAPt2j1inKYjoMDdC+EI9606	rigid:y90/CXdSnMt7p7yN7ook80rZx8g	false	myc tag:n-n	ha tag:n-n	-	-	psi-mi:"MI:0705"(anti tag western blot)	psi-mi:"MI:0705"(anti tag western blot)
uniprotkb:Q5T4F4	uniprotkb:Q5T4F4	intact:EBI-3892947|uniprotkb:Q5T4F1|uniprotkb:Q5T4F2|uniprotkb:Q5T4F3|uniprotkb:Q8N1K0|uniprotkb:Q8N6D6|uniprotkb:Q8NCA0|uniprotkb:Q8NDE4|uniprotkb:Q96M08|uniprotkb:B7Z404|uniprotkb:G8JLC3|uniprotkb:B7Z3S0|uniprotkb:B7Z626|uniprotkb:G8JLF0|uniprotkb:J3KP98|ensembl:ENSP00000377282|ensembl:ENSP00000506975	intact:EBI-3892947|uniprotkb:Q5T4F1|uniprotkb:Q5T4F2|uniprotkb:Q5T4F3|uniprotkb:Q8N1K0|uniprotkb:Q8N6D6|uniprotkb:Q8NCA0|uniprotkb:Q8NDE4|uniprotkb:Q96M08|uniprotkb:B7Z404|uniprotkb:G8JLC3|uniprotkb:B7Z3S0|uniprotkb:B7Z626|uniprotkb:G8JLF0|uniprotkb:J3KP98|ensembl:ENSP00000377282|ensembl:ENSP00000506975	psi-mi:zfy27_human(display_long)|uniprotkb:Spastic paraplegia 33 protein(gene name synonym)|uniprotkb:SPG33(gene name synonym)|uniprotkb:Zinc finger FYVE domain-containing protein 27(gene name synonym)|uniprotkb:ZFYVE27(gene name)|psi-mi:ZFYVE27(display_short)	psi-mi:zfy27_human(display_long)|uniprotkb:Spastic paraplegia 33 protein(gene name synonym)|uniprotkb:SPG33(gene name synonym)|uniprotkb:Zinc finger FYVE domain-containing protein 27(gene name synonym)|uniprotkb:ZFYVE27(gene name)|psi-mi:ZFYVE27(display_short)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Chang et al. (2013)	pubmed:23969831|imex:IM-27887	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0486"(UniProt)	intact:EBI-25506335|imex:IM-27887-3	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001002261.1|refseq:NP_001002262.1|refseq:NP_001167590.1|refseq:NP_001167591.1|refseq:NP_001167593.1|refseq:NP_653189.3|dip:DIP-61530N|refseq:XP_005269559.1|refseq:XP_005269560.1|refseq:XP_005269561.1|refseq:XP_005269563.1|refseq:NP_001167592.1|go:"GO:0016192"(vesicle-mediated transport)|ensembl:ENSG00000155256(gene)|ensembl:ENST00000393677(transcript)|go:"GO:0030176"(integral component of endoplasmic reticulum membrane)|ensembl:ENST00000684270(transcript)|go:"GO:0030424"(axon)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0030425"(dendrite)|go:"GO:0031175"(neuron projection development)|go:"GO:0032584"(growth cone membrane)|go:"GO:0005829"(cytosol)|go:"GO:0042802"(identical protein binding)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0043621"(protein self-association)|go:"GO:0045773"(positive regulation of axon extension)|go:"GO:0046872"(metal ion binding)|go:"GO:0048011"(neurotrophin TRK receptor signaling pathway)|go:"GO:0055038"(recycling endosome membrane)|go:"GO:0071782"(endoplasmic reticulum tubular network)|go:"GO:0071787"(endoplasmic reticulum tubular network formation)|go:"GO:0072659"(protein localization to plasma membrane)|interpro:IPR000306(Zinc finger, FYVE-type)|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017455(Zinc finger, FYVE-related)|interpro:IPR042405|rcsb pdb:1X4U	refseq:NP_001002261.1|refseq:NP_001002262.1|refseq:NP_001167590.1|refseq:NP_001167591.1|refseq:NP_001167593.1|refseq:NP_653189.3|dip:DIP-61530N|refseq:XP_005269559.1|refseq:XP_005269560.1|refseq:XP_005269561.1|refseq:XP_005269563.1|refseq:NP_001167592.1|go:"GO:0016192"(vesicle-mediated transport)|ensembl:ENSG00000155256(gene)|ensembl:ENST00000393677(transcript)|go:"GO:0030176"(integral component of endoplasmic reticulum membrane)|ensembl:ENST00000684270(transcript)|go:"GO:0030424"(axon)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0030425"(dendrite)|go:"GO:0031175"(neuron projection development)|go:"GO:0032584"(growth cone membrane)|go:"GO:0005829"(cytosol)|go:"GO:0042802"(identical protein binding)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0043621"(protein self-association)|go:"GO:0045773"(positive regulation of axon extension)|go:"GO:0046872"(metal ion binding)|go:"GO:0048011"(neurotrophin TRK receptor signaling pathway)|go:"GO:0055038"(recycling endosome membrane)|go:"GO:0071782"(endoplasmic reticulum tubular network)|go:"GO:0071787"(endoplasmic reticulum tubular network formation)|go:"GO:0072659"(protein localization to plasma membrane)|interpro:IPR000306(Zinc finger, FYVE-type)|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017455(Zinc finger, FYVE-related)|interpro:IPR042405|rcsb pdb:1X4U	-	-	-	figure legend:Supp Figs. 1B-D|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2020/04/08	2020/04/08	rogid:4ZValZeuAPt2j1inKYjoMDdC+EI9606	rogid:4ZValZeuAPt2j1inKYjoMDdC+EI9606	rigid:y90/CXdSnMt7p7yN7ook80rZx8g	false	myc tag:n-n|sufficient binding region:1-92	sufficient binding region:1-92|ha tag:n-n	-	-	psi-mi:"MI:0705"(anti tag western blot)	psi-mi:"MI:0705"(anti tag western blot)
uniprotkb:Q5T4F4	uniprotkb:Q9H902	intact:EBI-3892947|uniprotkb:Q5T4F1|uniprotkb:Q5T4F2|uniprotkb:Q5T4F3|uniprotkb:Q8N1K0|uniprotkb:Q8N6D6|uniprotkb:Q8NCA0|uniprotkb:Q8NDE4|uniprotkb:Q96M08|uniprotkb:B7Z404|uniprotkb:G8JLC3|uniprotkb:B7Z3S0|uniprotkb:B7Z626|uniprotkb:G8JLF0|uniprotkb:J3KP98|ensembl:ENSP00000377282|ensembl:ENSP00000506975	intact:EBI-1644241|uniprotkb:Q53TI0|uniprotkb:D6W5M2|uniprotkb:B7Z5R9|uniprotkb:B7Z4D7|uniprotkb:B7Z4F2|ensembl:ENSP00000165698	psi-mi:zfy27_human(display_long)|uniprotkb:Spastic paraplegia 33 protein(gene name synonym)|uniprotkb:SPG33(gene name synonym)|uniprotkb:Zinc finger FYVE domain-containing protein 27(gene name synonym)|uniprotkb:ZFYVE27(gene name)|psi-mi:ZFYVE27(display_short)	psi-mi:reep1_human(display_long)|uniprotkb:REEP1(gene name)|psi-mi:REEP1(display_short)|uniprotkb:C2orf23(gene name synonym)|uniprotkb:SPG31(gene name synonym)|uniprotkb:Spastic paraplegia 31 protein(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Chang et al. (2013)	pubmed:23969831|imex:IM-27887	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0486"(UniProt)	intact:EBI-25506463|imex:IM-27887-7	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001002261.1|refseq:NP_001002262.1|refseq:NP_001167590.1|refseq:NP_001167591.1|refseq:NP_001167593.1|refseq:NP_653189.3|dip:DIP-61530N|refseq:XP_005269559.1|refseq:XP_005269560.1|refseq:XP_005269561.1|refseq:XP_005269563.1|refseq:NP_001167592.1|go:"GO:0016192"(vesicle-mediated transport)|ensembl:ENSG00000155256(gene)|ensembl:ENST00000393677(transcript)|go:"GO:0030176"(integral component of endoplasmic reticulum membrane)|ensembl:ENST00000684270(transcript)|go:"GO:0030424"(axon)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0030425"(dendrite)|go:"GO:0031175"(neuron projection development)|go:"GO:0032584"(growth cone membrane)|go:"GO:0005829"(cytosol)|go:"GO:0042802"(identical protein binding)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0043621"(protein self-association)|go:"GO:0045773"(positive regulation of axon extension)|go:"GO:0046872"(metal ion binding)|go:"GO:0048011"(neurotrophin TRK receptor signaling pathway)|go:"GO:0055038"(recycling endosome membrane)|go:"GO:0071782"(endoplasmic reticulum tubular network)|go:"GO:0071787"(endoplasmic reticulum tubular network formation)|go:"GO:0072659"(protein localization to plasma membrane)|interpro:IPR000306(Zinc finger, FYVE-type)|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017455(Zinc finger, FYVE-related)|interpro:IPR042405|rcsb pdb:1X4U	refseq:NP_001158202.1|refseq:NP_001158203.1|refseq:NP_001158204.1|refseq:NP_075063.1|ensembl:ENSG00000068615(gene)|ensembl:ENST00000165698(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005881"(cytoplasmic microtubule)|go:"GO:0008017"(microtubule binding)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0031849"(olfactory receptor binding)|go:"GO:0031966"(mitochondrial membrane)|go:"GO:0051205"(protein insertion into membrane)|go:"GO:0071782"(endoplasmic reticulum tubular network)|go:"GO:0071786"(endoplasmic reticulum tubular network organization)|interpro:IPR004345(TB2/DP1 and HVA22 related protein)|reactome:R-HSA-381753	-	-	-	figure legend:Supp Fig. 3A|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2020/04/08	2020/04/08	rogid:4ZValZeuAPt2j1inKYjoMDdC+EI9606	rogid:um0CvKPQTL3ciOW3UqMhmrkUgaU9606	rigid:YHjRwLzVZqlTQvIUBv5dpGLpTJk	false	myc tag:n-n	ha tag:c-c	-	-	psi-mi:"MI:0705"(anti tag western blot)	psi-mi:"MI:0705"(anti tag western blot)
uniprotkb:Q5T4F4	uniprotkb:Q9H902	intact:EBI-3892947|uniprotkb:Q5T4F1|uniprotkb:Q5T4F2|uniprotkb:Q5T4F3|uniprotkb:Q8N1K0|uniprotkb:Q8N6D6|uniprotkb:Q8NCA0|uniprotkb:Q8NDE4|uniprotkb:Q96M08|uniprotkb:B7Z404|uniprotkb:G8JLC3|uniprotkb:B7Z3S0|uniprotkb:B7Z626|uniprotkb:G8JLF0|uniprotkb:J3KP98|ensembl:ENSP00000377282|ensembl:ENSP00000506975	intact:EBI-1644241|uniprotkb:Q53TI0|uniprotkb:D6W5M2|uniprotkb:B7Z5R9|uniprotkb:B7Z4D7|uniprotkb:B7Z4F2|ensembl:ENSP00000165698	psi-mi:zfy27_human(display_long)|uniprotkb:Spastic paraplegia 33 protein(gene name synonym)|uniprotkb:SPG33(gene name synonym)|uniprotkb:Zinc finger FYVE domain-containing protein 27(gene name synonym)|uniprotkb:ZFYVE27(gene name)|psi-mi:ZFYVE27(display_short)	psi-mi:reep1_human(display_long)|uniprotkb:REEP1(gene name)|psi-mi:REEP1(display_short)|uniprotkb:C2orf23(gene name synonym)|uniprotkb:SPG31(gene name synonym)|uniprotkb:Spastic paraplegia 31 protein(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Chang et al. (2013)	pubmed:23969831|imex:IM-27887	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0486"(UniProt)	intact:EBI-25506477|imex:IM-27887-9	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001002261.1|refseq:NP_001002262.1|refseq:NP_001167590.1|refseq:NP_001167591.1|refseq:NP_001167593.1|refseq:NP_653189.3|dip:DIP-61530N|refseq:XP_005269559.1|refseq:XP_005269560.1|refseq:XP_005269561.1|refseq:XP_005269563.1|refseq:NP_001167592.1|go:"GO:0016192"(vesicle-mediated transport)|ensembl:ENSG00000155256(gene)|ensembl:ENST00000393677(transcript)|go:"GO:0030176"(integral component of endoplasmic reticulum membrane)|ensembl:ENST00000684270(transcript)|go:"GO:0030424"(axon)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0030425"(dendrite)|go:"GO:0031175"(neuron projection development)|go:"GO:0032584"(growth cone membrane)|go:"GO:0005829"(cytosol)|go:"GO:0042802"(identical protein binding)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0043621"(protein self-association)|go:"GO:0045773"(positive regulation of axon extension)|go:"GO:0046872"(metal ion binding)|go:"GO:0048011"(neurotrophin TRK receptor signaling pathway)|go:"GO:0055038"(recycling endosome membrane)|go:"GO:0071782"(endoplasmic reticulum tubular network)|go:"GO:0071787"(endoplasmic reticulum tubular network formation)|go:"GO:0072659"(protein localization to plasma membrane)|interpro:IPR000306(Zinc finger, FYVE-type)|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017455(Zinc finger, FYVE-related)|interpro:IPR042405|rcsb pdb:1X4U	refseq:NP_001158202.1|refseq:NP_001158203.1|refseq:NP_001158204.1|refseq:NP_075063.1|ensembl:ENSG00000068615(gene)|ensembl:ENST00000165698(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005881"(cytoplasmic microtubule)|go:"GO:0008017"(microtubule binding)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0031849"(olfactory receptor binding)|go:"GO:0031966"(mitochondrial membrane)|go:"GO:0051205"(protein insertion into membrane)|go:"GO:0071782"(endoplasmic reticulum tubular network)|go:"GO:0071786"(endoplasmic reticulum tubular network organization)|interpro:IPR004345(TB2/DP1 and HVA22 related protein)|reactome:R-HSA-381753	-	-	-	figure legend:Supp Figs. 3A, 3D|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2020/04/08	2020/04/08	rogid:4ZValZeuAPt2j1inKYjoMDdC+EI9606	rogid:um0CvKPQTL3ciOW3UqMhmrkUgaU9606	rigid:YHjRwLzVZqlTQvIUBv5dpGLpTJk	false	sufficient binding region:1-205|myc tag:n-n	ha tag:c-c	-	-	psi-mi:"MI:0705"(anti tag western blot)	psi-mi:"MI:0705"(anti tag western blot)
uniprotkb:Q5T4F4	uniprotkb:Q00765	intact:EBI-3892947|uniprotkb:Q5T4F1|uniprotkb:Q5T4F2|uniprotkb:Q5T4F3|uniprotkb:Q8N1K0|uniprotkb:Q8N6D6|uniprotkb:Q8NCA0|uniprotkb:Q8NDE4|uniprotkb:Q96M08|uniprotkb:B7Z404|uniprotkb:G8JLC3|uniprotkb:B7Z3S0|uniprotkb:B7Z626|uniprotkb:G8JLF0|uniprotkb:J3KP98|ensembl:ENSP00000377282|ensembl:ENSP00000506975	intact:EBI-1549827|uniprotkb:Q04198|uniprotkb:Q5QGT0|uniprotkb:Q9BWH9|uniprotkb:D3DT04|uniprotkb:B7Z681|ensembl:ENSP00000368959	psi-mi:zfy27_human(display_long)|uniprotkb:Spastic paraplegia 33 protein(gene name synonym)|uniprotkb:SPG33(gene name synonym)|uniprotkb:Zinc finger FYVE domain-containing protein 27(gene name synonym)|uniprotkb:ZFYVE27(gene name)|psi-mi:ZFYVE27(display_short)	psi-mi:reep5_human(display_long)|uniprotkb:REEP5(gene name)|psi-mi:REEP5(display_short)|uniprotkb:C5orf18(gene name synonym)|uniprotkb:DP1(gene name synonym)|uniprotkb:TB2(gene name synonym)|uniprotkb:Polyposis locus protein 1(gene name synonym)|uniprotkb:Protein TB2(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Chang et al. (2013)	pubmed:23969831|imex:IM-27887	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0486"(UniProt)	intact:EBI-25506627|imex:IM-27887-25	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001002261.1|refseq:NP_001002262.1|refseq:NP_001167590.1|refseq:NP_001167591.1|refseq:NP_001167593.1|refseq:NP_653189.3|dip:DIP-61530N|refseq:XP_005269559.1|refseq:XP_005269560.1|refseq:XP_005269561.1|refseq:XP_005269563.1|refseq:NP_001167592.1|go:"GO:0016192"(vesicle-mediated transport)|ensembl:ENSG00000155256(gene)|ensembl:ENST00000393677(transcript)|go:"GO:0030176"(integral component of endoplasmic reticulum membrane)|ensembl:ENST00000684270(transcript)|go:"GO:0030424"(axon)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0030425"(dendrite)|go:"GO:0031175"(neuron projection development)|go:"GO:0032584"(growth cone membrane)|go:"GO:0005829"(cytosol)|go:"GO:0042802"(identical protein binding)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0043621"(protein self-association)|go:"GO:0045773"(positive regulation of axon extension)|go:"GO:0046872"(metal ion binding)|go:"GO:0048011"(neurotrophin TRK receptor signaling pathway)|go:"GO:0055038"(recycling endosome membrane)|go:"GO:0071782"(endoplasmic reticulum tubular network)|go:"GO:0071787"(endoplasmic reticulum tubular network formation)|go:"GO:0072659"(protein localization to plasma membrane)|interpro:IPR000306(Zinc finger, FYVE-type)|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017455(Zinc finger, FYVE-related)|interpro:IPR042405|rcsb pdb:1X4U	refseq:NP_005660.4|ensembl:ENSG00000129625(gene)|ensembl:ENST00000379638(transcript)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0007029"(endoplasmic reticulum organization)|go:"GO:0016021"(integral component of membrane)|go:"GO:0032386"(regulation of intracellular transport)|go:"GO:0071782"(endoplasmic reticulum tubular network)|interpro:IPR004345(TB2/DP1 and HVA22 related protein)|reactome:R-HSA-381753	-	-	-	figure legend:Supp Figs. 3B, 3E, 3F|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2020/04/08	2020/04/08	rogid:4ZValZeuAPt2j1inKYjoMDdC+EI9606	rogid:Z6Lzi37F0AfHZBnHri7k4EUpSRQ9606	rigid:HyEpT/SAX0c83tGBuehuLkWfDok	false	sufficient binding region:1-205|necessary binding region:67..67-205|myc tag:n-n	ha tag:c-c	-	-	psi-mi:"MI:0705"(anti tag western blot)	psi-mi:"MI:0705"(anti tag western blot)
uniprotkb:Q5T4F4	uniprotkb:Q00765	intact:EBI-3892947|uniprotkb:Q5T4F1|uniprotkb:Q5T4F2|uniprotkb:Q5T4F3|uniprotkb:Q8N1K0|uniprotkb:Q8N6D6|uniprotkb:Q8NCA0|uniprotkb:Q8NDE4|uniprotkb:Q96M08|uniprotkb:B7Z404|uniprotkb:G8JLC3|uniprotkb:B7Z3S0|uniprotkb:B7Z626|uniprotkb:G8JLF0|uniprotkb:J3KP98|ensembl:ENSP00000377282|ensembl:ENSP00000506975	intact:EBI-1549827|uniprotkb:Q04198|uniprotkb:Q5QGT0|uniprotkb:Q9BWH9|uniprotkb:D3DT04|uniprotkb:B7Z681|ensembl:ENSP00000368959	psi-mi:zfy27_human(display_long)|uniprotkb:Spastic paraplegia 33 protein(gene name synonym)|uniprotkb:SPG33(gene name synonym)|uniprotkb:Zinc finger FYVE domain-containing protein 27(gene name synonym)|uniprotkb:ZFYVE27(gene name)|psi-mi:ZFYVE27(display_short)	psi-mi:reep5_human(display_long)|uniprotkb:REEP5(gene name)|psi-mi:REEP5(display_short)|uniprotkb:C5orf18(gene name synonym)|uniprotkb:DP1(gene name synonym)|uniprotkb:TB2(gene name synonym)|uniprotkb:Polyposis locus protein 1(gene name synonym)|uniprotkb:Protein TB2(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Chang et al. (2013)	pubmed:23969831|imex:IM-27887	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0486"(UniProt)	intact:EBI-25506635|imex:IM-27887-11	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001002261.1|refseq:NP_001002262.1|refseq:NP_001167590.1|refseq:NP_001167591.1|refseq:NP_001167593.1|refseq:NP_653189.3|dip:DIP-61530N|refseq:XP_005269559.1|refseq:XP_005269560.1|refseq:XP_005269561.1|refseq:XP_005269563.1|refseq:NP_001167592.1|go:"GO:0016192"(vesicle-mediated transport)|ensembl:ENSG00000155256(gene)|ensembl:ENST00000393677(transcript)|go:"GO:0030176"(integral component of endoplasmic reticulum membrane)|ensembl:ENST00000684270(transcript)|go:"GO:0030424"(axon)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0030425"(dendrite)|go:"GO:0031175"(neuron projection development)|go:"GO:0032584"(growth cone membrane)|go:"GO:0005829"(cytosol)|go:"GO:0042802"(identical protein binding)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0043621"(protein self-association)|go:"GO:0045773"(positive regulation of axon extension)|go:"GO:0046872"(metal ion binding)|go:"GO:0048011"(neurotrophin TRK receptor signaling pathway)|go:"GO:0055038"(recycling endosome membrane)|go:"GO:0071782"(endoplasmic reticulum tubular network)|go:"GO:0071787"(endoplasmic reticulum tubular network formation)|go:"GO:0072659"(protein localization to plasma membrane)|interpro:IPR000306(Zinc finger, FYVE-type)|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017455(Zinc finger, FYVE-related)|interpro:IPR042405|rcsb pdb:1X4U	refseq:NP_005660.4|ensembl:ENSG00000129625(gene)|ensembl:ENST00000379638(transcript)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0007029"(endoplasmic reticulum organization)|go:"GO:0016021"(integral component of membrane)|go:"GO:0032386"(regulation of intracellular transport)|go:"GO:0071782"(endoplasmic reticulum tubular network)|interpro:IPR004345(TB2/DP1 and HVA22 related protein)|reactome:R-HSA-381753	-	-	-	figure legend:Supp Fig. 3B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2020/04/08	2020/04/08	rogid:4ZValZeuAPt2j1inKYjoMDdC+EI9606	rogid:Z6Lzi37F0AfHZBnHri7k4EUpSRQ9606	rigid:HyEpT/SAX0c83tGBuehuLkWfDok	false	myc tag:n-n	ha tag:c-c	-	-	psi-mi:"MI:0705"(anti tag western blot)	psi-mi:"MI:0705"(anti tag western blot)
uniprotkb:Q5T4F4	uniprotkb:Q9UBP0	intact:EBI-3892947|uniprotkb:Q5T4F1|uniprotkb:Q5T4F2|uniprotkb:Q5T4F3|uniprotkb:Q8N1K0|uniprotkb:Q8N6D6|uniprotkb:Q8NCA0|uniprotkb:Q8NDE4|uniprotkb:Q96M08|uniprotkb:B7Z404|uniprotkb:G8JLC3|uniprotkb:B7Z3S0|uniprotkb:B7Z626|uniprotkb:G8JLF0|uniprotkb:J3KP98|ensembl:ENSP00000377282|ensembl:ENSP00000506975	intact:EBI-1222832|uniprotkb:Q9UPR9|uniprotkb:A7E2A7|ensembl:ENSP00000320885	psi-mi:zfy27_human(display_long)|uniprotkb:Spastic paraplegia 33 protein(gene name synonym)|uniprotkb:SPG33(gene name synonym)|uniprotkb:Zinc finger FYVE domain-containing protein 27(gene name synonym)|uniprotkb:ZFYVE27(gene name)|psi-mi:ZFYVE27(display_short)	psi-mi:spast_human(display_long)|uniprotkb:SPAST(gene name)|psi-mi:SPAST(display_short)|uniprotkb:KIAA1083(gene name synonym)|uniprotkb:SPG4(gene name synonym)|uniprotkb:ADPSP(gene name synonym)|uniprotkb:FSP2(gene name synonym)|uniprotkb:Spastic paraplegia 4 protein(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Chang et al. (2013)	pubmed:23969831|imex:IM-27887	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0486"(UniProt)	intact:EBI-25506678|imex:IM-27887-27	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001002261.1|refseq:NP_001002262.1|refseq:NP_001167590.1|refseq:NP_001167591.1|refseq:NP_001167593.1|refseq:NP_653189.3|dip:DIP-61530N|refseq:XP_005269559.1|refseq:XP_005269560.1|refseq:XP_005269561.1|refseq:XP_005269563.1|refseq:NP_001167592.1|go:"GO:0016192"(vesicle-mediated transport)|ensembl:ENSG00000155256(gene)|ensembl:ENST00000393677(transcript)|go:"GO:0030176"(integral component of endoplasmic reticulum membrane)|ensembl:ENST00000684270(transcript)|go:"GO:0030424"(axon)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0030425"(dendrite)|go:"GO:0031175"(neuron projection development)|go:"GO:0032584"(growth cone membrane)|go:"GO:0005829"(cytosol)|go:"GO:0042802"(identical protein binding)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0043621"(protein self-association)|go:"GO:0045773"(positive regulation of axon extension)|go:"GO:0046872"(metal ion binding)|go:"GO:0048011"(neurotrophin TRK receptor signaling pathway)|go:"GO:0055038"(recycling endosome membrane)|go:"GO:0071782"(endoplasmic reticulum tubular network)|go:"GO:0071787"(endoplasmic reticulum tubular network formation)|go:"GO:0072659"(protein localization to plasma membrane)|interpro:IPR000306(Zinc finger, FYVE-type)|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017455(Zinc finger, FYVE-related)|interpro:IPR042405|rcsb pdb:1X4U	refseq:NP_055761.2|refseq:NP_955468.1|dip:DIP-38418N|ensembl:ENSG00000021574(gene)|ensembl:ENST00000315285(transcript)|go:"GO:0000281"(mitotic cytokinesis)|go:"GO:0001578"(microtubule bundle formation)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005811"(lipid droplet)|go:"GO:0005813"(centrosome)|go:"GO:0005819"(spindle)|go:"GO:0005829"(cytosol)|go:"GO:0005874"(microtubule)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0007084"(mitotic nuclear membrane reassembly)|go:"GO:0007409"(axonogenesis)|go:"GO:0008017"(microtubule binding)|go:"GO:0008089"(anterograde axonal transport)|go:"GO:0008152"(metabolic process)|go:"GO:0008568"(microtubule-severing ATPase activity)|go:"GO:0010458"(exit from mitosis)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016853"(isomerase activity)|go:"GO:0019896"(axonal transport of mitochondrion)|go:"GO:0030496"(midbody)|go:"GO:0031117"(positive regulation of microtubule depolymerization)|go:"GO:0031122"(cytoplasmic microtubule organization)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0031468"(nuclear membrane reassembly)|go:"GO:0031965"(nuclear membrane)|go:"GO:0032467"(positive regulation of cytokinesis)|go:"GO:0032506"(cytokinetic process)|go:"GO:0034214"(protein hexamerization)|go:"GO:0043014"(alpha-tubulin binding)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0048487"(beta-tubulin binding)|go:"GO:0051013"(microtubule severing)|go:"GO:0051228"(mitotic spindle disassembly)|go:"GO:0051260"(protein homooligomerization)|go:"GO:0061640"(cytoskeleton-dependent cytokinesis)|rcsb pdb:6PEN|go:"GO:0070062"(extracellular exosome)|reactome:R-HSA-9668328|go:"GO:0071782"(endoplasmic reticulum tubular network)|go:"GO:0090148"(membrane fission)|go:"GO:1904115"(axon cytoplasm)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR003959(AAA ATPase, core)|interpro:IPR003960(AAA ATPase, conserved site)|interpro:IPR007330(MIT)|interpro:IPR015415(Vps4 oligomerisation, C-terminal)|interpro:IPR017179(Spastin)|interpro:IPR027417|interpro:IPR035106|interpro:IPR041569|rcsb pdb:3EAB|rcsb pdb:3VFD|rcsb pdb:5Z6Q|rcsb pdb:5Z6R|rcsb pdb:6PEK	-	-	-	figure legend:Supp Figs. 4D|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2020/04/08	2020/04/08	rogid:4ZValZeuAPt2j1inKYjoMDdC+EI9606	rogid:E8b4FF6pWwyVd9teIInSCY4RzQE9606	rigid:AEWVysyGn/Vr9McmRq8X2W+pt1A	false	myc tag:n-n|sufficient binding region:1-205	ha tag:c-c	-	-	psi-mi:"MI:0705"(anti tag western blot)	psi-mi:"MI:0705"(anti tag western blot)
uniprotkb:Q5T4F4	uniprotkb:Q9UBP0	intact:EBI-3892947|uniprotkb:Q5T4F1|uniprotkb:Q5T4F2|uniprotkb:Q5T4F3|uniprotkb:Q8N1K0|uniprotkb:Q8N6D6|uniprotkb:Q8NCA0|uniprotkb:Q8NDE4|uniprotkb:Q96M08|uniprotkb:B7Z404|uniprotkb:G8JLC3|uniprotkb:B7Z3S0|uniprotkb:B7Z626|uniprotkb:G8JLF0|uniprotkb:J3KP98|ensembl:ENSP00000377282|ensembl:ENSP00000506975	intact:EBI-1222832|uniprotkb:Q9UPR9|uniprotkb:A7E2A7|ensembl:ENSP00000320885	psi-mi:zfy27_human(display_long)|uniprotkb:Spastic paraplegia 33 protein(gene name synonym)|uniprotkb:SPG33(gene name synonym)|uniprotkb:Zinc finger FYVE domain-containing protein 27(gene name synonym)|uniprotkb:ZFYVE27(gene name)|psi-mi:ZFYVE27(display_short)	psi-mi:spast_human(display_long)|uniprotkb:SPAST(gene name)|psi-mi:SPAST(display_short)|uniprotkb:KIAA1083(gene name synonym)|uniprotkb:SPG4(gene name synonym)|uniprotkb:ADPSP(gene name synonym)|uniprotkb:FSP2(gene name synonym)|uniprotkb:Spastic paraplegia 4 protein(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Chang et al. (2013)	pubmed:23969831|imex:IM-27887	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0486"(UniProt)	intact:EBI-25506689|imex:IM-27887-29	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001002261.1|refseq:NP_001002262.1|refseq:NP_001167590.1|refseq:NP_001167591.1|refseq:NP_001167593.1|refseq:NP_653189.3|dip:DIP-61530N|refseq:XP_005269559.1|refseq:XP_005269560.1|refseq:XP_005269561.1|refseq:XP_005269563.1|refseq:NP_001167592.1|go:"GO:0016192"(vesicle-mediated transport)|ensembl:ENSG00000155256(gene)|ensembl:ENST00000393677(transcript)|go:"GO:0030176"(integral component of endoplasmic reticulum membrane)|ensembl:ENST00000684270(transcript)|go:"GO:0030424"(axon)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0030425"(dendrite)|go:"GO:0031175"(neuron projection development)|go:"GO:0032584"(growth cone membrane)|go:"GO:0005829"(cytosol)|go:"GO:0042802"(identical protein binding)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0043621"(protein self-association)|go:"GO:0045773"(positive regulation of axon extension)|go:"GO:0046872"(metal ion binding)|go:"GO:0048011"(neurotrophin TRK receptor signaling pathway)|go:"GO:0055038"(recycling endosome membrane)|go:"GO:0071782"(endoplasmic reticulum tubular network)|go:"GO:0071787"(endoplasmic reticulum tubular network formation)|go:"GO:0072659"(protein localization to plasma membrane)|interpro:IPR000306(Zinc finger, FYVE-type)|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017455(Zinc finger, FYVE-related)|interpro:IPR042405|rcsb pdb:1X4U	refseq:NP_055761.2|refseq:NP_955468.1|dip:DIP-38418N|ensembl:ENSG00000021574(gene)|ensembl:ENST00000315285(transcript)|go:"GO:0000281"(mitotic cytokinesis)|go:"GO:0001578"(microtubule bundle formation)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005811"(lipid droplet)|go:"GO:0005813"(centrosome)|go:"GO:0005819"(spindle)|go:"GO:0005829"(cytosol)|go:"GO:0005874"(microtubule)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0007084"(mitotic nuclear membrane reassembly)|go:"GO:0007409"(axonogenesis)|go:"GO:0008017"(microtubule binding)|go:"GO:0008089"(anterograde axonal transport)|go:"GO:0008152"(metabolic process)|go:"GO:0008568"(microtubule-severing ATPase activity)|go:"GO:0010458"(exit from mitosis)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016853"(isomerase activity)|go:"GO:0019896"(axonal transport of mitochondrion)|go:"GO:0030496"(midbody)|go:"GO:0031117"(positive regulation of microtubule depolymerization)|go:"GO:0031122"(cytoplasmic microtubule organization)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0031468"(nuclear membrane reassembly)|go:"GO:0031965"(nuclear membrane)|go:"GO:0032467"(positive regulation of cytokinesis)|go:"GO:0032506"(cytokinetic process)|go:"GO:0034214"(protein hexamerization)|go:"GO:0043014"(alpha-tubulin binding)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0048487"(beta-tubulin binding)|go:"GO:0051013"(microtubule severing)|go:"GO:0051228"(mitotic spindle disassembly)|go:"GO:0051260"(protein homooligomerization)|go:"GO:0061640"(cytoskeleton-dependent cytokinesis)|rcsb pdb:6PEN|go:"GO:0070062"(extracellular exosome)|reactome:R-HSA-9668328|go:"GO:0071782"(endoplasmic reticulum tubular network)|go:"GO:0090148"(membrane fission)|go:"GO:1904115"(axon cytoplasm)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR003959(AAA ATPase, core)|interpro:IPR003960(AAA ATPase, conserved site)|interpro:IPR007330(MIT)|interpro:IPR015415(Vps4 oligomerisation, C-terminal)|interpro:IPR017179(Spastin)|interpro:IPR027417|interpro:IPR035106|interpro:IPR041569|rcsb pdb:3EAB|rcsb pdb:3VFD|rcsb pdb:5Z6Q|rcsb pdb:5Z6R|rcsb pdb:6PEK	-	-	-	figure legend:Supp Figs. 4C|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2020/04/08	2020/04/08	rogid:4ZValZeuAPt2j1inKYjoMDdC+EI9606	rogid:E8b4FF6pWwyVd9teIInSCY4RzQE9606	rigid:AEWVysyGn/Vr9McmRq8X2W+pt1A	false	myc tag:n-n	ha tag:c-c|necessary binding region:1-86	-	-	psi-mi:"MI:0705"(anti tag western blot)	psi-mi:"MI:0705"(anti tag western blot)
uniprotkb:Q5T4F4	uniprotkb:Q8WXF7	intact:EBI-3892947|uniprotkb:Q5T4F1|uniprotkb:Q5T4F2|uniprotkb:Q5T4F3|uniprotkb:Q8N1K0|uniprotkb:Q8N6D6|uniprotkb:Q8NCA0|uniprotkb:Q8NDE4|uniprotkb:Q96M08|uniprotkb:B7Z404|uniprotkb:G8JLC3|uniprotkb:B7Z3S0|uniprotkb:B7Z626|uniprotkb:G8JLF0|uniprotkb:J3KP98|ensembl:ENSP00000377282|ensembl:ENSP00000506975	intact:EBI-2410266|uniprotkb:A6NND5|uniprotkb:O95890|uniprotkb:Q96FK0|uniprotkb:A8K2C0|uniprotkb:G5E9T1|uniprotkb:Q69YH7|ensembl:ENSP00000351155	psi-mi:zfy27_human(display_long)|uniprotkb:Spastic paraplegia 33 protein(gene name synonym)|uniprotkb:SPG33(gene name synonym)|uniprotkb:Zinc finger FYVE domain-containing protein 27(gene name synonym)|uniprotkb:ZFYVE27(gene name)|psi-mi:ZFYVE27(display_short)	psi-mi:atla1_human(display_long)|uniprotkb:ATL1(gene name)|psi-mi:ATL1(display_short)|uniprotkb:GBP3(gene name synonym)|uniprotkb:SPG3A(gene name synonym)|uniprotkb:Spastic paraplegia 3 protein A(gene name synonym)|uniprotkb:Guanine nucleotide-binding protein 3(gene name synonym)|uniprotkb:GTP-binding protein 3(gene name synonym)|uniprotkb:Brain-specific GTP-binding protein(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Chang et al. (2013)	pubmed:23969831|imex:IM-27887	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0486"(UniProt)	intact:EBI-25506714|imex:IM-27887-31	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001002261.1|refseq:NP_001002262.1|refseq:NP_001167590.1|refseq:NP_001167591.1|refseq:NP_001167593.1|refseq:NP_653189.3|dip:DIP-61530N|refseq:XP_005269559.1|refseq:XP_005269560.1|refseq:XP_005269561.1|refseq:XP_005269563.1|refseq:NP_001167592.1|go:"GO:0016192"(vesicle-mediated transport)|ensembl:ENSG00000155256(gene)|ensembl:ENST00000393677(transcript)|go:"GO:0030176"(integral component of endoplasmic reticulum membrane)|ensembl:ENST00000684270(transcript)|go:"GO:0030424"(axon)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0030425"(dendrite)|go:"GO:0031175"(neuron projection development)|go:"GO:0032584"(growth cone membrane)|go:"GO:0005829"(cytosol)|go:"GO:0042802"(identical protein binding)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0043621"(protein self-association)|go:"GO:0045773"(positive regulation of axon extension)|go:"GO:0046872"(metal ion binding)|go:"GO:0048011"(neurotrophin TRK receptor signaling pathway)|go:"GO:0055038"(recycling endosome membrane)|go:"GO:0071782"(endoplasmic reticulum tubular network)|go:"GO:0071787"(endoplasmic reticulum tubular network formation)|go:"GO:0072659"(protein localization to plasma membrane)|interpro:IPR000306(Zinc finger, FYVE-type)|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017455(Zinc finger, FYVE-related)|interpro:IPR042405|rcsb pdb:1X4U	refseq:NP_001121185.1|refseq:NP_056999.2|refseq:NP_853629.2|dip:DIP-53502N|ensembl:ENSG00000198513(gene)|ensembl:ENST00000358385(transcript)|go:"GO:0000137"(Golgi cis cisterna)|go:"GO:0000139"(Golgi membrane)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0007029"(endoplasmic reticulum organization)|go:"GO:0007409"(axonogenesis)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030424"(axon)|go:"GO:0042802"(identical protein binding)|go:"GO:0051260"(protein homooligomerization)|go:"GO:0071782"(endoplasmic reticulum tubular network)|go:"GO:0098826"(endoplasmic reticulum tubular network membrane)|go:"GO:1990809"(endoplasmic reticulum tubular network membrane organization)|interpro:IPR015894(Guanylate-binding protein, N-terminal)|interpro:IPR027417|interpro:IPR030386|interpro:IPR036543|mint:Q8WXF7|rcsb pdb:3Q5D|rcsb pdb:3Q5E|rcsb pdb:3QNU|rcsb pdb:3QOF|rcsb pdb:4IDN|rcsb pdb:4IDO|rcsb pdb:4IDP|rcsb pdb:4IDQ|rcsb pdb:6B9D|rcsb pdb:6B9E|rcsb pdb:6B9F|rcsb pdb:6B9G|rcsb pdb:6XJN	-	-	-	figure legend:Supp Fig.5A|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2020/04/08	2020/04/08	rogid:4ZValZeuAPt2j1inKYjoMDdC+EI9606	rogid:xHgqrEBVA57vg40bCwdpIrhaWIw9606	rigid:V+wepSJLpYLrWGLPO3TcVyK+IyM	false	ha tag:n-n	myc tag:n-n	-	-	psi-mi:"MI:0705"(anti tag western blot)	psi-mi:"MI:0705"(anti tag western blot)
uniprotkb:Q5T4F4	uniprotkb:Q8WXF7	intact:EBI-3892947|uniprotkb:Q5T4F1|uniprotkb:Q5T4F2|uniprotkb:Q5T4F3|uniprotkb:Q8N1K0|uniprotkb:Q8N6D6|uniprotkb:Q8NCA0|uniprotkb:Q8NDE4|uniprotkb:Q96M08|uniprotkb:B7Z404|uniprotkb:G8JLC3|uniprotkb:B7Z3S0|uniprotkb:B7Z626|uniprotkb:G8JLF0|uniprotkb:J3KP98|ensembl:ENSP00000377282|ensembl:ENSP00000506975	intact:EBI-2410266|uniprotkb:A6NND5|uniprotkb:O95890|uniprotkb:Q96FK0|uniprotkb:A8K2C0|uniprotkb:G5E9T1|uniprotkb:Q69YH7|ensembl:ENSP00000351155	psi-mi:zfy27_human(display_long)|uniprotkb:Spastic paraplegia 33 protein(gene name synonym)|uniprotkb:SPG33(gene name synonym)|uniprotkb:Zinc finger FYVE domain-containing protein 27(gene name synonym)|uniprotkb:ZFYVE27(gene name)|psi-mi:ZFYVE27(display_short)	psi-mi:atla1_human(display_long)|uniprotkb:ATL1(gene name)|psi-mi:ATL1(display_short)|uniprotkb:GBP3(gene name synonym)|uniprotkb:SPG3A(gene name synonym)|uniprotkb:Spastic paraplegia 3 protein A(gene name synonym)|uniprotkb:Guanine nucleotide-binding protein 3(gene name synonym)|uniprotkb:GTP-binding protein 3(gene name synonym)|uniprotkb:Brain-specific GTP-binding protein(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Chang et al. (2013)	pubmed:23969831|imex:IM-27887	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0486"(UniProt)	intact:EBI-25506959|imex:IM-27887-15	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001002261.1|refseq:NP_001002262.1|refseq:NP_001167590.1|refseq:NP_001167591.1|refseq:NP_001167593.1|refseq:NP_653189.3|dip:DIP-61530N|refseq:XP_005269559.1|refseq:XP_005269560.1|refseq:XP_005269561.1|refseq:XP_005269563.1|refseq:NP_001167592.1|go:"GO:0016192"(vesicle-mediated transport)|ensembl:ENSG00000155256(gene)|ensembl:ENST00000393677(transcript)|go:"GO:0030176"(integral component of endoplasmic reticulum membrane)|ensembl:ENST00000684270(transcript)|go:"GO:0030424"(axon)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0030425"(dendrite)|go:"GO:0031175"(neuron projection development)|go:"GO:0032584"(growth cone membrane)|go:"GO:0005829"(cytosol)|go:"GO:0042802"(identical protein binding)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0043621"(protein self-association)|go:"GO:0045773"(positive regulation of axon extension)|go:"GO:0046872"(metal ion binding)|go:"GO:0048011"(neurotrophin TRK receptor signaling pathway)|go:"GO:0055038"(recycling endosome membrane)|go:"GO:0071782"(endoplasmic reticulum tubular network)|go:"GO:0071787"(endoplasmic reticulum tubular network formation)|go:"GO:0072659"(protein localization to plasma membrane)|interpro:IPR000306(Zinc finger, FYVE-type)|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017455(Zinc finger, FYVE-related)|interpro:IPR042405|rcsb pdb:1X4U	refseq:NP_001121185.1|refseq:NP_056999.2|refseq:NP_853629.2|dip:DIP-53502N|ensembl:ENSG00000198513(gene)|ensembl:ENST00000358385(transcript)|go:"GO:0000137"(Golgi cis cisterna)|go:"GO:0000139"(Golgi membrane)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0007029"(endoplasmic reticulum organization)|go:"GO:0007409"(axonogenesis)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030424"(axon)|go:"GO:0042802"(identical protein binding)|go:"GO:0051260"(protein homooligomerization)|go:"GO:0071782"(endoplasmic reticulum tubular network)|go:"GO:0098826"(endoplasmic reticulum tubular network membrane)|go:"GO:1990809"(endoplasmic reticulum tubular network membrane organization)|interpro:IPR015894(Guanylate-binding protein, N-terminal)|interpro:IPR027417|interpro:IPR030386|interpro:IPR036543|mint:Q8WXF7|rcsb pdb:3Q5D|rcsb pdb:3Q5E|rcsb pdb:3QNU|rcsb pdb:3QOF|rcsb pdb:4IDN|rcsb pdb:4IDO|rcsb pdb:4IDP|rcsb pdb:4IDQ|rcsb pdb:6B9D|rcsb pdb:6B9E|rcsb pdb:6B9F|rcsb pdb:6B9G|rcsb pdb:6XJN	-	-	-	figure legend:Supp Figs. 5B, 5D|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2020/04/08	2020/04/08	rogid:4ZValZeuAPt2j1inKYjoMDdC+EI9606	rogid:xHgqrEBVA57vg40bCwdpIrhaWIw9606	rigid:V+wepSJLpYLrWGLPO3TcVyK+IyM	false	sufficient binding region:1-205|ha tag:n-n	myc tag:n-n|mutation with no effect:469-469|mutation with no effect:495-495|mutation with no effect:80-80|mutation with no effect:519-519	-	-	psi-mi:"MI:0705"(anti tag western blot)	psi-mi:"MI:0705"(anti tag western blot)
uniprotkb:Q5T4F4	uniprotkb:Q8NHH9	intact:EBI-3892947|uniprotkb:Q5T4F1|uniprotkb:Q5T4F2|uniprotkb:Q5T4F3|uniprotkb:Q8N1K0|uniprotkb:Q8N6D6|uniprotkb:Q8NCA0|uniprotkb:Q8NDE4|uniprotkb:Q96M08|uniprotkb:B7Z404|uniprotkb:G8JLC3|uniprotkb:B7Z3S0|uniprotkb:B7Z626|uniprotkb:G8JLF0|uniprotkb:J3KP98|ensembl:ENSP00000377282|ensembl:ENSP00000506975	intact:EBI-2410430|uniprotkb:B7Z1X2|ensembl:ENSP00000368237|uniprotkb:Q4ZG30|uniprotkb:Q7Z630|uniprotkb:Q8NHH8|uniprotkb:Q9H5M7|intact:EBI-2559696|uniprotkb:B7Z7X8|intact:EBI-11081412	psi-mi:zfy27_human(display_long)|uniprotkb:Spastic paraplegia 33 protein(gene name synonym)|uniprotkb:SPG33(gene name synonym)|uniprotkb:Zinc finger FYVE domain-containing protein 27(gene name synonym)|uniprotkb:ZFYVE27(gene name)|psi-mi:ZFYVE27(display_short)	psi-mi:atla2_human(display_long)|uniprotkb:ATL2(gene name)|psi-mi:ATL2(display_short)|uniprotkb:ARL6IP2(gene name synonym)|uniprotkb:ADP-ribosylation factor-like protein 6-interacting protein 2(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Chang et al. (2013)	pubmed:23969831|imex:IM-27887	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0486"(UniProt)	intact:EBI-25506987|imex:IM-27887-17	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001002261.1|refseq:NP_001002262.1|refseq:NP_001167590.1|refseq:NP_001167591.1|refseq:NP_001167593.1|refseq:NP_653189.3|dip:DIP-61530N|refseq:XP_005269559.1|refseq:XP_005269560.1|refseq:XP_005269561.1|refseq:XP_005269563.1|refseq:NP_001167592.1|go:"GO:0016192"(vesicle-mediated transport)|ensembl:ENSG00000155256(gene)|ensembl:ENST00000393677(transcript)|go:"GO:0030176"(integral component of endoplasmic reticulum membrane)|ensembl:ENST00000684270(transcript)|go:"GO:0030424"(axon)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0030425"(dendrite)|go:"GO:0031175"(neuron projection development)|go:"GO:0032584"(growth cone membrane)|go:"GO:0005829"(cytosol)|go:"GO:0042802"(identical protein binding)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0043621"(protein self-association)|go:"GO:0045773"(positive regulation of axon extension)|go:"GO:0046872"(metal ion binding)|go:"GO:0048011"(neurotrophin TRK receptor signaling pathway)|go:"GO:0055038"(recycling endosome membrane)|go:"GO:0071782"(endoplasmic reticulum tubular network)|go:"GO:0071787"(endoplasmic reticulum tubular network formation)|go:"GO:0072659"(protein localization to plasma membrane)|interpro:IPR000306(Zinc finger, FYVE-type)|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017455(Zinc finger, FYVE-related)|interpro:IPR042405|rcsb pdb:1X4U	ensembl:ENSG00000119787(gene)|ensembl:ENST00000378954(transcript)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0007029"(endoplasmic reticulum organization)|go:"GO:0007030"(Golgi organization)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0051260"(protein homooligomerization)|go:"GO:0098826"(endoplasmic reticulum tubular network membrane)|go:"GO:1990809"(endoplasmic reticulum tubular network membrane organization)|interpro:IPR003191(Guanylate-binding protein, C-terminal)|interpro:IPR015894(Guanylate-binding protein, N-terminal)|interpro:IPR027417|interpro:IPR030386|interpro:IPR036543|mint:Q8NHH9|refseq:NP_001295005.1|refseq:NP_001129145.1|refseq:NP_071769.2|refseq:NP_001317387.1|refseq:NP_001317388.1|refseq:NP_001317389.1	-	-	-	figure legend:Supp Figs.5A|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2020/04/08	2020/04/08	rogid:4ZValZeuAPt2j1inKYjoMDdC+EI9606	rogid:MGye5g/TWQQv39oFMuhF+PUZcRM9606	rigid:rrX4CKwdZ7Py7JfL4S7MaOmKAWY	false	ha tag:n-n	myc tag:n-n	-	-	psi-mi:"MI:0705"(anti tag western blot)	psi-mi:"MI:0705"(anti tag western blot)
uniprotkb:Q5T4F4	uniprotkb:Q6DD88	intact:EBI-3892947|uniprotkb:Q5T4F1|uniprotkb:Q5T4F2|uniprotkb:Q5T4F3|uniprotkb:Q8N1K0|uniprotkb:Q8N6D6|uniprotkb:Q8NCA0|uniprotkb:Q8NDE4|uniprotkb:Q96M08|uniprotkb:B7Z404|uniprotkb:G8JLC3|uniprotkb:B7Z3S0|uniprotkb:B7Z626|uniprotkb:G8JLF0|uniprotkb:J3KP98|ensembl:ENSP00000377282|ensembl:ENSP00000506975	intact:EBI-6165882|ensembl:ENSP00000381844|uniprotkb:Q8N7W5|uniprotkb:Q9H8Q5|uniprotkb:Q9UFL1	psi-mi:zfy27_human(display_long)|uniprotkb:Spastic paraplegia 33 protein(gene name synonym)|uniprotkb:SPG33(gene name synonym)|uniprotkb:Zinc finger FYVE domain-containing protein 27(gene name synonym)|uniprotkb:ZFYVE27(gene name)|psi-mi:ZFYVE27(display_short)	psi-mi:atla3_human(display_long)|uniprotkb:ATL3(gene name)|psi-mi:ATL3(display_short)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Chang et al. (2013)	pubmed:23969831|imex:IM-27887	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0486"(UniProt)	intact:EBI-25507014|imex:IM-27887-19	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001002261.1|refseq:NP_001002262.1|refseq:NP_001167590.1|refseq:NP_001167591.1|refseq:NP_001167593.1|refseq:NP_653189.3|dip:DIP-61530N|refseq:XP_005269559.1|refseq:XP_005269560.1|refseq:XP_005269561.1|refseq:XP_005269563.1|refseq:NP_001167592.1|go:"GO:0016192"(vesicle-mediated transport)|ensembl:ENSG00000155256(gene)|ensembl:ENST00000393677(transcript)|go:"GO:0030176"(integral component of endoplasmic reticulum membrane)|ensembl:ENST00000684270(transcript)|go:"GO:0030424"(axon)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0030425"(dendrite)|go:"GO:0031175"(neuron projection development)|go:"GO:0032584"(growth cone membrane)|go:"GO:0005829"(cytosol)|go:"GO:0042802"(identical protein binding)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0043621"(protein self-association)|go:"GO:0045773"(positive regulation of axon extension)|go:"GO:0046872"(metal ion binding)|go:"GO:0048011"(neurotrophin TRK receptor signaling pathway)|go:"GO:0055038"(recycling endosome membrane)|go:"GO:0071782"(endoplasmic reticulum tubular network)|go:"GO:0071787"(endoplasmic reticulum tubular network formation)|go:"GO:0072659"(protein localization to plasma membrane)|interpro:IPR000306(Zinc finger, FYVE-type)|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017455(Zinc finger, FYVE-related)|interpro:IPR042405|rcsb pdb:1X4U	go:"GO:0007029"(endoplasmic reticulum organization)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0051260"(protein homooligomerization)|go:"GO:0071782"(endoplasmic reticulum tubular network)|go:"GO:0098826"(endoplasmic reticulum tubular network membrane)|go:"GO:1903373"(positive regulation of endoplasmic reticulum tubular network organization)|interpro:IPR003191(Guanylate-binding protein, C-terminal)|interpro:IPR015894(Guanylate-binding protein, N-terminal)|interpro:IPR027417|interpro:IPR030386|interpro:IPR036543|mint:Q6DD88|rcsb pdb:5VGR|rcsb pdb:6XJO|go:"GO:0007030"(Golgi organization)|ensembl:ENSG00000184743(gene)|ensembl:ENST00000398868(transcript)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005783"(endoplasmic reticulum)|refseq:NP_001276977.1|refseq:NP_056274.3	-	-	-	figure legend:Supp Figs.5A|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2020/04/08	2020/04/08	rogid:4ZValZeuAPt2j1inKYjoMDdC+EI9606	rogid:9vgpZvUg5aFAZyNiZ2pdEPn/J7o9606	rigid:4DNNlRu/C268xI1l+75MlKHGwu4	false	ha tag:n-n	myc tag:n-n	-	-	psi-mi:"MI:0705"(anti tag western blot)	psi-mi:"MI:0705"(anti tag western blot)
uniprotkb:Q5T4F4	uniprotkb:Q8WXF7	intact:EBI-3892947|uniprotkb:Q5T4F1|uniprotkb:Q5T4F2|uniprotkb:Q5T4F3|uniprotkb:Q8N1K0|uniprotkb:Q8N6D6|uniprotkb:Q8NCA0|uniprotkb:Q8NDE4|uniprotkb:Q96M08|uniprotkb:B7Z404|uniprotkb:G8JLC3|uniprotkb:B7Z3S0|uniprotkb:B7Z626|uniprotkb:G8JLF0|uniprotkb:J3KP98|ensembl:ENSP00000377282|ensembl:ENSP00000506975	intact:EBI-2410266|uniprotkb:A6NND5|uniprotkb:O95890|uniprotkb:Q96FK0|uniprotkb:A8K2C0|uniprotkb:G5E9T1|uniprotkb:Q69YH7|ensembl:ENSP00000351155	psi-mi:zfy27_human(display_long)|uniprotkb:Spastic paraplegia 33 protein(gene name synonym)|uniprotkb:SPG33(gene name synonym)|uniprotkb:Zinc finger FYVE domain-containing protein 27(gene name synonym)|uniprotkb:ZFYVE27(gene name)|psi-mi:ZFYVE27(display_short)	psi-mi:atla1_human(display_long)|uniprotkb:ATL1(gene name)|psi-mi:ATL1(display_short)|uniprotkb:GBP3(gene name synonym)|uniprotkb:SPG3A(gene name synonym)|uniprotkb:Spastic paraplegia 3 protein A(gene name synonym)|uniprotkb:Guanine nucleotide-binding protein 3(gene name synonym)|uniprotkb:GTP-binding protein 3(gene name synonym)|uniprotkb:Brain-specific GTP-binding protein(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Chang et al. (2013)	pubmed:23969831|imex:IM-27887	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0486"(UniProt)	intact:EBI-25684093|imex:IM-27887-35	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001002261.1|refseq:NP_001002262.1|refseq:NP_001167590.1|refseq:NP_001167591.1|refseq:NP_001167593.1|refseq:NP_653189.3|dip:DIP-61530N|refseq:XP_005269559.1|refseq:XP_005269560.1|refseq:XP_005269561.1|refseq:XP_005269563.1|refseq:NP_001167592.1|go:"GO:0016192"(vesicle-mediated transport)|ensembl:ENSG00000155256(gene)|ensembl:ENST00000393677(transcript)|go:"GO:0030176"(integral component of endoplasmic reticulum membrane)|ensembl:ENST00000684270(transcript)|go:"GO:0030424"(axon)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0030425"(dendrite)|go:"GO:0031175"(neuron projection development)|go:"GO:0032584"(growth cone membrane)|go:"GO:0005829"(cytosol)|go:"GO:0042802"(identical protein binding)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0043621"(protein self-association)|go:"GO:0045773"(positive regulation of axon extension)|go:"GO:0046872"(metal ion binding)|go:"GO:0048011"(neurotrophin TRK receptor signaling pathway)|go:"GO:0055038"(recycling endosome membrane)|go:"GO:0071782"(endoplasmic reticulum tubular network)|go:"GO:0071787"(endoplasmic reticulum tubular network formation)|go:"GO:0072659"(protein localization to plasma membrane)|interpro:IPR000306(Zinc finger, FYVE-type)|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017455(Zinc finger, FYVE-related)|interpro:IPR042405|rcsb pdb:1X4U	refseq:NP_001121185.1|refseq:NP_056999.2|refseq:NP_853629.2|dip:DIP-53502N|ensembl:ENSG00000198513(gene)|ensembl:ENST00000358385(transcript)|go:"GO:0000137"(Golgi cis cisterna)|go:"GO:0000139"(Golgi membrane)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0007029"(endoplasmic reticulum organization)|go:"GO:0007409"(axonogenesis)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030424"(axon)|go:"GO:0042802"(identical protein binding)|go:"GO:0051260"(protein homooligomerization)|go:"GO:0071782"(endoplasmic reticulum tubular network)|go:"GO:0098826"(endoplasmic reticulum tubular network membrane)|go:"GO:1990809"(endoplasmic reticulum tubular network membrane organization)|interpro:IPR015894(Guanylate-binding protein, N-terminal)|interpro:IPR027417|interpro:IPR030386|interpro:IPR036543|mint:Q8WXF7|rcsb pdb:3Q5D|rcsb pdb:3Q5E|rcsb pdb:3QNU|rcsb pdb:3QOF|rcsb pdb:4IDN|rcsb pdb:4IDO|rcsb pdb:4IDP|rcsb pdb:4IDQ|rcsb pdb:6B9D|rcsb pdb:6B9E|rcsb pdb:6B9F|rcsb pdb:6B9G|rcsb pdb:6XJN	-	-	-	figure legend:Supp Fig 5C|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2020/04/08	2020/06/24	rogid:4ZValZeuAPt2j1inKYjoMDdC+EI9606	rogid:xHgqrEBVA57vg40bCwdpIrhaWIw9606	rigid:V+wepSJLpYLrWGLPO3TcVyK+IyM	false	myc tag:n-n	sufficient binding region:448-558|ha tag:?-?	-	-	psi-mi:"MI:0705"(anti tag western blot)	psi-mi:"MI:0705"(anti tag western blot)
uniprotkb:Q5T4F4	uniprotkb:Q00765	intact:EBI-3892947|uniprotkb:Q5T4F1|uniprotkb:Q5T4F2|uniprotkb:Q5T4F3|uniprotkb:Q8N1K0|uniprotkb:Q8N6D6|uniprotkb:Q8NCA0|uniprotkb:Q8NDE4|uniprotkb:Q96M08|uniprotkb:B7Z404|uniprotkb:G8JLC3|uniprotkb:B7Z3S0|uniprotkb:B7Z626|uniprotkb:G8JLF0|uniprotkb:J3KP98|ensembl:ENSP00000377282|ensembl:ENSP00000506975	intact:EBI-1549827|uniprotkb:Q04198|uniprotkb:Q5QGT0|uniprotkb:Q9BWH9|uniprotkb:D3DT04|uniprotkb:B7Z681|ensembl:ENSP00000368959	psi-mi:zfy27_human(display_long)|uniprotkb:Spastic paraplegia 33 protein(gene name synonym)|uniprotkb:SPG33(gene name synonym)|uniprotkb:Zinc finger FYVE domain-containing protein 27(gene name synonym)|uniprotkb:ZFYVE27(gene name)|psi-mi:ZFYVE27(display_short)	psi-mi:reep5_human(display_long)|uniprotkb:REEP5(gene name)|psi-mi:REEP5(display_short)|uniprotkb:C5orf18(gene name synonym)|uniprotkb:DP1(gene name synonym)|uniprotkb:TB2(gene name synonym)|uniprotkb:Polyposis locus protein 1(gene name synonym)|uniprotkb:Protein TB2(gene name synonym)	psi-mi:"MI:0663"(confocal microscopy)	Chang et al. (2013)	pubmed:23969831|imex:IM-27887	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0403"(colocalization)	psi-mi:"MI:0486"(UniProt)	intact:EBI-25506376|imex:IM-27887-23	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001002261.1|refseq:NP_001002262.1|refseq:NP_001167590.1|refseq:NP_001167591.1|refseq:NP_001167593.1|refseq:NP_653189.3|dip:DIP-61530N|refseq:XP_005269559.1|refseq:XP_005269560.1|refseq:XP_005269561.1|refseq:XP_005269563.1|refseq:NP_001167592.1|go:"GO:0016192"(vesicle-mediated transport)|ensembl:ENSG00000155256(gene)|ensembl:ENST00000393677(transcript)|go:"GO:0030176"(integral component of endoplasmic reticulum membrane)|ensembl:ENST00000684270(transcript)|go:"GO:0030424"(axon)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0030425"(dendrite)|go:"GO:0031175"(neuron projection development)|go:"GO:0032584"(growth cone membrane)|go:"GO:0005829"(cytosol)|go:"GO:0042802"(identical protein binding)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0043621"(protein self-association)|go:"GO:0045773"(positive regulation of axon extension)|go:"GO:0046872"(metal ion binding)|go:"GO:0048011"(neurotrophin TRK receptor signaling pathway)|go:"GO:0055038"(recycling endosome membrane)|go:"GO:0071782"(endoplasmic reticulum tubular network)|go:"GO:0071787"(endoplasmic reticulum tubular network formation)|go:"GO:0072659"(protein localization to plasma membrane)|interpro:IPR000306(Zinc finger, FYVE-type)|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017455(Zinc finger, FYVE-related)|interpro:IPR042405|rcsb pdb:1X4U	refseq:NP_005660.4|ensembl:ENSG00000129625(gene)|ensembl:ENST00000379638(transcript)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0007029"(endoplasmic reticulum organization)|go:"GO:0016021"(integral component of membrane)|go:"GO:0032386"(regulation of intracellular transport)|go:"GO:0071782"(endoplasmic reticulum tubular network)|interpro:IPR004345(TB2/DP1 and HVA22 related protein)|reactome:R-HSA-381753	go:"GO:0005783"(endoplasmic reticulum)	-	-	figure legend:Fig 2A, Supp Figs. 2, 5F|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2020/04/08	2020/04/08	rogid:4ZValZeuAPt2j1inKYjoMDdC+EI9606	rogid:Z6Lzi37F0AfHZBnHri7k4EUpSRQ9606	rigid:HyEpT/SAX0c83tGBuehuLkWfDok	false	mutation with no effect:191-191|ha tag:n-n|mutation decreasing interaction strength:200-200	-	-	-	psi-mi:"MI:1200"(immunocytochemistry)	psi-mi:"MI:1200"(immunocytochemistry)
uniprotkb:Q5T4F4	uniprotkb:Q6DD88	intact:EBI-3892947|uniprotkb:Q5T4F1|uniprotkb:Q5T4F2|uniprotkb:Q5T4F3|uniprotkb:Q8N1K0|uniprotkb:Q8N6D6|uniprotkb:Q8NCA0|uniprotkb:Q8NDE4|uniprotkb:Q96M08|uniprotkb:B7Z404|uniprotkb:G8JLC3|uniprotkb:B7Z3S0|uniprotkb:B7Z626|uniprotkb:G8JLF0|uniprotkb:J3KP98|ensembl:ENSP00000377282|ensembl:ENSP00000506975	intact:EBI-6165882|ensembl:ENSP00000381844|uniprotkb:Q8N7W5|uniprotkb:Q9H8Q5|uniprotkb:Q9UFL1	psi-mi:zfy27_human(display_long)|uniprotkb:Spastic paraplegia 33 protein(gene name synonym)|uniprotkb:SPG33(gene name synonym)|uniprotkb:Zinc finger FYVE domain-containing protein 27(gene name synonym)|uniprotkb:ZFYVE27(gene name)|psi-mi:ZFYVE27(display_short)	psi-mi:atla3_human(display_long)|uniprotkb:ATL3(gene name)|psi-mi:ATL3(display_short)	psi-mi:"MI:0663"(confocal microscopy)	Chang et al. (2013)	pubmed:23969831|imex:IM-27887	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0403"(colocalization)	psi-mi:"MI:0486"(UniProt)	intact:EBI-25506396|imex:IM-27887-5	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001002261.1|refseq:NP_001002262.1|refseq:NP_001167590.1|refseq:NP_001167591.1|refseq:NP_001167593.1|refseq:NP_653189.3|dip:DIP-61530N|refseq:XP_005269559.1|refseq:XP_005269560.1|refseq:XP_005269561.1|refseq:XP_005269563.1|refseq:NP_001167592.1|go:"GO:0016192"(vesicle-mediated transport)|ensembl:ENSG00000155256(gene)|ensembl:ENST00000393677(transcript)|go:"GO:0030176"(integral component of endoplasmic reticulum membrane)|ensembl:ENST00000684270(transcript)|go:"GO:0030424"(axon)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0030425"(dendrite)|go:"GO:0031175"(neuron projection development)|go:"GO:0032584"(growth cone membrane)|go:"GO:0005829"(cytosol)|go:"GO:0042802"(identical protein binding)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0043621"(protein self-association)|go:"GO:0045773"(positive regulation of axon extension)|go:"GO:0046872"(metal ion binding)|go:"GO:0048011"(neurotrophin TRK receptor signaling pathway)|go:"GO:0055038"(recycling endosome membrane)|go:"GO:0071782"(endoplasmic reticulum tubular network)|go:"GO:0071787"(endoplasmic reticulum tubular network formation)|go:"GO:0072659"(protein localization to plasma membrane)|interpro:IPR000306(Zinc finger, FYVE-type)|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017455(Zinc finger, FYVE-related)|interpro:IPR042405|rcsb pdb:1X4U	go:"GO:0007029"(endoplasmic reticulum organization)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0051260"(protein homooligomerization)|go:"GO:0071782"(endoplasmic reticulum tubular network)|go:"GO:0098826"(endoplasmic reticulum tubular network membrane)|go:"GO:1903373"(positive regulation of endoplasmic reticulum tubular network organization)|interpro:IPR003191(Guanylate-binding protein, C-terminal)|interpro:IPR015894(Guanylate-binding protein, N-terminal)|interpro:IPR027417|interpro:IPR030386|interpro:IPR036543|mint:Q6DD88|rcsb pdb:5VGR|rcsb pdb:6XJO|go:"GO:0007030"(Golgi organization)|ensembl:ENSG00000184743(gene)|ensembl:ENST00000398868(transcript)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005783"(endoplasmic reticulum)|refseq:NP_001276977.1|refseq:NP_056274.3	-	-	-	figure legend:Fig 2A|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2020/04/08	2020/04/08	rogid:4ZValZeuAPt2j1inKYjoMDdC+EI9606	rogid:9vgpZvUg5aFAZyNiZ2pdEPn/J7o9606	rigid:4DNNlRu/C268xI1l+75MlKHGwu4	false	-	myc tag:n-n	-	-	psi-mi:"MI:1200"(immunocytochemistry)	psi-mi:"MI:1200"(immunocytochemistry)
uniprotkb:Q5T4F4	uniprotkb:Q9UBP0	intact:EBI-3892947|uniprotkb:Q5T4F1|uniprotkb:Q5T4F2|uniprotkb:Q5T4F3|uniprotkb:Q8N1K0|uniprotkb:Q8N6D6|uniprotkb:Q8NCA0|uniprotkb:Q8NDE4|uniprotkb:Q96M08|uniprotkb:B7Z404|uniprotkb:G8JLC3|uniprotkb:B7Z3S0|uniprotkb:B7Z626|uniprotkb:G8JLF0|uniprotkb:J3KP98|ensembl:ENSP00000377282|ensembl:ENSP00000506975	intact:EBI-1222832|uniprotkb:Q9UPR9|uniprotkb:A7E2A7|ensembl:ENSP00000320885	psi-mi:zfy27_human(display_long)|uniprotkb:Spastic paraplegia 33 protein(gene name synonym)|uniprotkb:SPG33(gene name synonym)|uniprotkb:Zinc finger FYVE domain-containing protein 27(gene name synonym)|uniprotkb:ZFYVE27(gene name)|psi-mi:ZFYVE27(display_short)	psi-mi:spast_human(display_long)|uniprotkb:SPAST(gene name)|psi-mi:SPAST(display_short)|uniprotkb:KIAA1083(gene name synonym)|uniprotkb:SPG4(gene name synonym)|uniprotkb:ADPSP(gene name synonym)|uniprotkb:FSP2(gene name synonym)|uniprotkb:Spastic paraplegia 4 protein(gene name synonym)	psi-mi:"MI:0663"(confocal microscopy)	Chang et al. (2013)	pubmed:23969831|imex:IM-27887	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0403"(colocalization)	psi-mi:"MI:0486"(UniProt)	intact:EBI-25506699|imex:IM-27887-13	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001002261.1|refseq:NP_001002262.1|refseq:NP_001167590.1|refseq:NP_001167591.1|refseq:NP_001167593.1|refseq:NP_653189.3|dip:DIP-61530N|refseq:XP_005269559.1|refseq:XP_005269560.1|refseq:XP_005269561.1|refseq:XP_005269563.1|refseq:NP_001167592.1|go:"GO:0016192"(vesicle-mediated transport)|ensembl:ENSG00000155256(gene)|ensembl:ENST00000393677(transcript)|go:"GO:0030176"(integral component of endoplasmic reticulum membrane)|ensembl:ENST00000684270(transcript)|go:"GO:0030424"(axon)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0030425"(dendrite)|go:"GO:0031175"(neuron projection development)|go:"GO:0032584"(growth cone membrane)|go:"GO:0005829"(cytosol)|go:"GO:0042802"(identical protein binding)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0043621"(protein self-association)|go:"GO:0045773"(positive regulation of axon extension)|go:"GO:0046872"(metal ion binding)|go:"GO:0048011"(neurotrophin TRK receptor signaling pathway)|go:"GO:0055038"(recycling endosome membrane)|go:"GO:0071782"(endoplasmic reticulum tubular network)|go:"GO:0071787"(endoplasmic reticulum tubular network formation)|go:"GO:0072659"(protein localization to plasma membrane)|interpro:IPR000306(Zinc finger, FYVE-type)|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017455(Zinc finger, FYVE-related)|interpro:IPR042405|rcsb pdb:1X4U	refseq:NP_055761.2|refseq:NP_955468.1|dip:DIP-38418N|ensembl:ENSG00000021574(gene)|ensembl:ENST00000315285(transcript)|go:"GO:0000281"(mitotic cytokinesis)|go:"GO:0001578"(microtubule bundle formation)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005811"(lipid droplet)|go:"GO:0005813"(centrosome)|go:"GO:0005819"(spindle)|go:"GO:0005829"(cytosol)|go:"GO:0005874"(microtubule)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0007084"(mitotic nuclear membrane reassembly)|go:"GO:0007409"(axonogenesis)|go:"GO:0008017"(microtubule binding)|go:"GO:0008089"(anterograde axonal transport)|go:"GO:0008152"(metabolic process)|go:"GO:0008568"(microtubule-severing ATPase activity)|go:"GO:0010458"(exit from mitosis)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016853"(isomerase activity)|go:"GO:0019896"(axonal transport of mitochondrion)|go:"GO:0030496"(midbody)|go:"GO:0031117"(positive regulation of microtubule depolymerization)|go:"GO:0031122"(cytoplasmic microtubule organization)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0031468"(nuclear membrane reassembly)|go:"GO:0031965"(nuclear membrane)|go:"GO:0032467"(positive regulation of cytokinesis)|go:"GO:0032506"(cytokinetic process)|go:"GO:0034214"(protein hexamerization)|go:"GO:0043014"(alpha-tubulin binding)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0048487"(beta-tubulin binding)|go:"GO:0051013"(microtubule severing)|go:"GO:0051228"(mitotic spindle disassembly)|go:"GO:0051260"(protein homooligomerization)|go:"GO:0061640"(cytoskeleton-dependent cytokinesis)|rcsb pdb:6PEN|go:"GO:0070062"(extracellular exosome)|reactome:R-HSA-9668328|go:"GO:0071782"(endoplasmic reticulum tubular network)|go:"GO:0090148"(membrane fission)|go:"GO:1904115"(axon cytoplasm)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR003959(AAA ATPase, core)|interpro:IPR003960(AAA ATPase, conserved site)|interpro:IPR007330(MIT)|interpro:IPR015415(Vps4 oligomerisation, C-terminal)|interpro:IPR017179(Spastin)|interpro:IPR027417|interpro:IPR035106|interpro:IPR041569|rcsb pdb:3EAB|rcsb pdb:3VFD|rcsb pdb:5Z6Q|rcsb pdb:5Z6R|rcsb pdb:6PEK	go:"GO:0005783"(endoplasmic reticulum)	-	-	figure legend:Supp Figs. 4B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2020/04/08	2020/04/08	rogid:4ZValZeuAPt2j1inKYjoMDdC+EI9606	rogid:E8b4FF6pWwyVd9teIInSCY4RzQE9606	rigid:AEWVysyGn/Vr9McmRq8X2W+pt1A	false	ha tag:n-n	myc tag:n-n|necessary binding region:1-86	-	-	psi-mi:"MI:1200"(immunocytochemistry)	psi-mi:"MI:1200"(immunocytochemistry)
uniprotkb:Q5T4F4	uniprotkb:Q8WXF7	intact:EBI-3892947|uniprotkb:Q5T4F1|uniprotkb:Q5T4F2|uniprotkb:Q5T4F3|uniprotkb:Q8N1K0|uniprotkb:Q8N6D6|uniprotkb:Q8NCA0|uniprotkb:Q8NDE4|uniprotkb:Q96M08|uniprotkb:B7Z404|uniprotkb:G8JLC3|uniprotkb:B7Z3S0|uniprotkb:B7Z626|uniprotkb:G8JLF0|uniprotkb:J3KP98|ensembl:ENSP00000377282|ensembl:ENSP00000506975	intact:EBI-2410266|uniprotkb:A6NND5|uniprotkb:O95890|uniprotkb:Q96FK0|uniprotkb:A8K2C0|uniprotkb:G5E9T1|uniprotkb:Q69YH7|ensembl:ENSP00000351155	psi-mi:zfy27_human(display_long)|uniprotkb:Spastic paraplegia 33 protein(gene name synonym)|uniprotkb:SPG33(gene name synonym)|uniprotkb:Zinc finger FYVE domain-containing protein 27(gene name synonym)|uniprotkb:ZFYVE27(gene name)|psi-mi:ZFYVE27(display_short)	psi-mi:atla1_human(display_long)|uniprotkb:ATL1(gene name)|psi-mi:ATL1(display_short)|uniprotkb:GBP3(gene name synonym)|uniprotkb:SPG3A(gene name synonym)|uniprotkb:Spastic paraplegia 3 protein A(gene name synonym)|uniprotkb:Guanine nucleotide-binding protein 3(gene name synonym)|uniprotkb:GTP-binding protein 3(gene name synonym)|uniprotkb:Brain-specific GTP-binding protein(gene name synonym)	psi-mi:"MI:0663"(confocal microscopy)	Chang et al. (2013)	pubmed:23969831|imex:IM-27887	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0403"(colocalization)	psi-mi:"MI:0486"(UniProt)	intact:EBI-25510681|imex:IM-27887-33	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001002261.1|refseq:NP_001002262.1|refseq:NP_001167590.1|refseq:NP_001167591.1|refseq:NP_001167593.1|refseq:NP_653189.3|dip:DIP-61530N|refseq:XP_005269559.1|refseq:XP_005269560.1|refseq:XP_005269561.1|refseq:XP_005269563.1|refseq:NP_001167592.1|go:"GO:0016192"(vesicle-mediated transport)|ensembl:ENSG00000155256(gene)|ensembl:ENST00000393677(transcript)|go:"GO:0030176"(integral component of endoplasmic reticulum membrane)|ensembl:ENST00000684270(transcript)|go:"GO:0030424"(axon)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0030425"(dendrite)|go:"GO:0031175"(neuron projection development)|go:"GO:0032584"(growth cone membrane)|go:"GO:0005829"(cytosol)|go:"GO:0042802"(identical protein binding)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0043621"(protein self-association)|go:"GO:0045773"(positive regulation of axon extension)|go:"GO:0046872"(metal ion binding)|go:"GO:0048011"(neurotrophin TRK receptor signaling pathway)|go:"GO:0055038"(recycling endosome membrane)|go:"GO:0071782"(endoplasmic reticulum tubular network)|go:"GO:0071787"(endoplasmic reticulum tubular network formation)|go:"GO:0072659"(protein localization to plasma membrane)|interpro:IPR000306(Zinc finger, FYVE-type)|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017455(Zinc finger, FYVE-related)|interpro:IPR042405|rcsb pdb:1X4U	refseq:NP_001121185.1|refseq:NP_056999.2|refseq:NP_853629.2|dip:DIP-53502N|ensembl:ENSG00000198513(gene)|ensembl:ENST00000358385(transcript)|go:"GO:0000137"(Golgi cis cisterna)|go:"GO:0000139"(Golgi membrane)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0007029"(endoplasmic reticulum organization)|go:"GO:0007409"(axonogenesis)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030424"(axon)|go:"GO:0042802"(identical protein binding)|go:"GO:0051260"(protein homooligomerization)|go:"GO:0071782"(endoplasmic reticulum tubular network)|go:"GO:0098826"(endoplasmic reticulum tubular network membrane)|go:"GO:1990809"(endoplasmic reticulum tubular network membrane organization)|interpro:IPR015894(Guanylate-binding protein, N-terminal)|interpro:IPR027417|interpro:IPR030386|interpro:IPR036543|mint:Q8WXF7|rcsb pdb:3Q5D|rcsb pdb:3Q5E|rcsb pdb:3QNU|rcsb pdb:3QOF|rcsb pdb:4IDN|rcsb pdb:4IDO|rcsb pdb:4IDP|rcsb pdb:4IDQ|rcsb pdb:6B9D|rcsb pdb:6B9E|rcsb pdb:6B9F|rcsb pdb:6B9G|rcsb pdb:6XJN	go:"GO:0005783"(endoplasmic reticulum)	-	-	figure legend:Supp Fig. 5G|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2020/04/08	2020/04/14	rogid:4ZValZeuAPt2j1inKYjoMDdC+EI9606	rogid:xHgqrEBVA57vg40bCwdpIrhaWIw9606	rigid:V+wepSJLpYLrWGLPO3TcVyK+IyM	false	ha tag:n-n|mutation with no effect:191-191	myc tag:n-n	-	-	psi-mi:"MI:1200"(immunocytochemistry)	psi-mi:"MI:1200"(immunocytochemistry)
uniprotkb:Q9UBP0	uniprotkb:Q00765	intact:EBI-1222832|uniprotkb:Q9UPR9|uniprotkb:A7E2A7|ensembl:ENSP00000320885	intact:EBI-1549827|uniprotkb:Q04198|uniprotkb:Q5QGT0|uniprotkb:Q9BWH9|uniprotkb:D3DT04|uniprotkb:B7Z681|ensembl:ENSP00000368959	psi-mi:spast_human(display_long)|uniprotkb:SPAST(gene name)|psi-mi:SPAST(display_short)|uniprotkb:KIAA1083(gene name synonym)|uniprotkb:SPG4(gene name synonym)|uniprotkb:ADPSP(gene name synonym)|uniprotkb:FSP2(gene name synonym)|uniprotkb:Spastic paraplegia 4 protein(gene name synonym)	psi-mi:reep5_human(display_long)|uniprotkb:REEP5(gene name)|psi-mi:REEP5(display_short)|uniprotkb:C5orf18(gene name synonym)|uniprotkb:DP1(gene name synonym)|uniprotkb:TB2(gene name synonym)|uniprotkb:Polyposis locus protein 1(gene name synonym)|uniprotkb:Protein TB2(gene name synonym)	psi-mi:"MI:0663"(confocal microscopy)	Chang et al. (2013)	pubmed:23969831|imex:IM-27887	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0403"(colocalization)	psi-mi:"MI:0486"(UniProt)	intact:EBI-25683908|imex:IM-27887-34	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_055761.2|refseq:NP_955468.1|dip:DIP-38418N|ensembl:ENSG00000021574(gene)|ensembl:ENST00000315285(transcript)|go:"GO:0000281"(mitotic cytokinesis)|go:"GO:0001578"(microtubule bundle formation)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005811"(lipid droplet)|go:"GO:0005813"(centrosome)|go:"GO:0005819"(spindle)|go:"GO:0005829"(cytosol)|go:"GO:0005874"(microtubule)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0007084"(mitotic nuclear membrane reassembly)|go:"GO:0007409"(axonogenesis)|go:"GO:0008017"(microtubule binding)|go:"GO:0008089"(anterograde axonal transport)|go:"GO:0008152"(metabolic process)|go:"GO:0008568"(microtubule-severing ATPase activity)|go:"GO:0010458"(exit from mitosis)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016853"(isomerase activity)|go:"GO:0019896"(axonal transport of mitochondrion)|go:"GO:0030496"(midbody)|go:"GO:0031117"(positive regulation of microtubule depolymerization)|go:"GO:0031122"(cytoplasmic microtubule organization)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0031468"(nuclear membrane reassembly)|go:"GO:0031965"(nuclear membrane)|go:"GO:0032467"(positive regulation of cytokinesis)|go:"GO:0032506"(cytokinetic process)|go:"GO:0034214"(protein hexamerization)|go:"GO:0043014"(alpha-tubulin binding)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0048487"(beta-tubulin binding)|go:"GO:0051013"(microtubule severing)|go:"GO:0051228"(mitotic spindle disassembly)|go:"GO:0051260"(protein homooligomerization)|go:"GO:0061640"(cytoskeleton-dependent cytokinesis)|rcsb pdb:6PEN|go:"GO:0070062"(extracellular exosome)|reactome:R-HSA-9668328|go:"GO:0071782"(endoplasmic reticulum tubular network)|go:"GO:0090148"(membrane fission)|go:"GO:1904115"(axon cytoplasm)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR003959(AAA ATPase, core)|interpro:IPR003960(AAA ATPase, conserved site)|interpro:IPR007330(MIT)|interpro:IPR015415(Vps4 oligomerisation, C-terminal)|interpro:IPR017179(Spastin)|interpro:IPR027417|interpro:IPR035106|interpro:IPR041569|rcsb pdb:3EAB|rcsb pdb:3VFD|rcsb pdb:5Z6Q|rcsb pdb:5Z6R|rcsb pdb:6PEK	refseq:NP_005660.4|ensembl:ENSG00000129625(gene)|ensembl:ENST00000379638(transcript)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0007029"(endoplasmic reticulum organization)|go:"GO:0016021"(integral component of membrane)|go:"GO:0032386"(regulation of intracellular transport)|go:"GO:0071782"(endoplasmic reticulum tubular network)|interpro:IPR004345(TB2/DP1 and HVA22 related protein)|reactome:R-HSA-381753	go:"GO:0005783"(endoplasmic reticulum)	-	-	figure legend:Supp Figs. 4B|comment:Recombinant M1 spastin was codistributed with endogenous REEP5 and recombinant HA-protrudin along ER tubules, whereas M87 spastin was dispersed throughout the cytoplasm.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2020/04/08	2020/06/23	rogid:E8b4FF6pWwyVd9teIInSCY4RzQE9606	rogid:Z6Lzi37F0AfHZBnHri7k4EUpSRQ9606	rigid:P/wDgaTRgEAms5JnFmQr6ptiuVw	false	myc tag:n-n	-	-	-	psi-mi:"MI:1200"(immunocytochemistry)	psi-mi:"MI:1200"(immunocytochemistry)
uniprotkb:Q5T4F4	uniprotkb:Q8WXF7	intact:EBI-3892947|uniprotkb:Q5T4F1|uniprotkb:Q5T4F2|uniprotkb:Q5T4F3|uniprotkb:Q8N1K0|uniprotkb:Q8N6D6|uniprotkb:Q8NCA0|uniprotkb:Q8NDE4|uniprotkb:Q96M08|uniprotkb:B7Z404|uniprotkb:G8JLC3|uniprotkb:B7Z3S0|uniprotkb:B7Z626|uniprotkb:G8JLF0|uniprotkb:J3KP98|ensembl:ENSP00000377282|ensembl:ENSP00000506975	intact:EBI-2410266|uniprotkb:A6NND5|uniprotkb:O95890|uniprotkb:Q96FK0|uniprotkb:A8K2C0|uniprotkb:G5E9T1|uniprotkb:Q69YH7|ensembl:ENSP00000351155	psi-mi:zfy27_human(display_long)|uniprotkb:Spastic paraplegia 33 protein(gene name synonym)|uniprotkb:SPG33(gene name synonym)|uniprotkb:Zinc finger FYVE domain-containing protein 27(gene name synonym)|uniprotkb:ZFYVE27(gene name)|psi-mi:ZFYVE27(display_short)	psi-mi:atla1_human(display_long)|uniprotkb:ATL1(gene name)|psi-mi:ATL1(display_short)|uniprotkb:GBP3(gene name synonym)|uniprotkb:SPG3A(gene name synonym)|uniprotkb:Spastic paraplegia 3 protein A(gene name synonym)|uniprotkb:Guanine nucleotide-binding protein 3(gene name synonym)|uniprotkb:GTP-binding protein 3(gene name synonym)|uniprotkb:Brain-specific GTP-binding protein(gene name synonym)	psi-mi:"MI:0663"(confocal microscopy)	Chang et al. (2013)	pubmed:23969831|imex:IM-27887	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0403"(colocalization)	psi-mi:"MI:0486"(UniProt)	intact:EBI-25684103|imex:IM-27887-37	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001002261.1|refseq:NP_001002262.1|refseq:NP_001167590.1|refseq:NP_001167591.1|refseq:NP_001167593.1|refseq:NP_653189.3|dip:DIP-61530N|refseq:XP_005269559.1|refseq:XP_005269560.1|refseq:XP_005269561.1|refseq:XP_005269563.1|refseq:NP_001167592.1|go:"GO:0016192"(vesicle-mediated transport)|ensembl:ENSG00000155256(gene)|ensembl:ENST00000393677(transcript)|go:"GO:0030176"(integral component of endoplasmic reticulum membrane)|ensembl:ENST00000684270(transcript)|go:"GO:0030424"(axon)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0030425"(dendrite)|go:"GO:0031175"(neuron projection development)|go:"GO:0032584"(growth cone membrane)|go:"GO:0005829"(cytosol)|go:"GO:0042802"(identical protein binding)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0043621"(protein self-association)|go:"GO:0045773"(positive regulation of axon extension)|go:"GO:0046872"(metal ion binding)|go:"GO:0048011"(neurotrophin TRK receptor signaling pathway)|go:"GO:0055038"(recycling endosome membrane)|go:"GO:0071782"(endoplasmic reticulum tubular network)|go:"GO:0071787"(endoplasmic reticulum tubular network formation)|go:"GO:0072659"(protein localization to plasma membrane)|interpro:IPR000306(Zinc finger, FYVE-type)|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017455(Zinc finger, FYVE-related)|interpro:IPR042405|rcsb pdb:1X4U	refseq:NP_001121185.1|refseq:NP_056999.2|refseq:NP_853629.2|dip:DIP-53502N|ensembl:ENSG00000198513(gene)|ensembl:ENST00000358385(transcript)|go:"GO:0000137"(Golgi cis cisterna)|go:"GO:0000139"(Golgi membrane)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0007029"(endoplasmic reticulum organization)|go:"GO:0007409"(axonogenesis)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030424"(axon)|go:"GO:0042802"(identical protein binding)|go:"GO:0051260"(protein homooligomerization)|go:"GO:0071782"(endoplasmic reticulum tubular network)|go:"GO:0098826"(endoplasmic reticulum tubular network membrane)|go:"GO:1990809"(endoplasmic reticulum tubular network membrane organization)|interpro:IPR015894(Guanylate-binding protein, N-terminal)|interpro:IPR027417|interpro:IPR030386|interpro:IPR036543|mint:Q8WXF7|rcsb pdb:3Q5D|rcsb pdb:3Q5E|rcsb pdb:3QNU|rcsb pdb:3QOF|rcsb pdb:4IDN|rcsb pdb:4IDO|rcsb pdb:4IDP|rcsb pdb:4IDQ|rcsb pdb:6B9D|rcsb pdb:6B9E|rcsb pdb:6B9F|rcsb pdb:6B9G|rcsb pdb:6XJN	go:"GO:0005783"(endoplasmic reticulum)	-	-	figure legend:Supp Fig. 5E|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2020/04/08	2020/06/24	rogid:4ZValZeuAPt2j1inKYjoMDdC+EI9606	rogid:xHgqrEBVA57vg40bCwdpIrhaWIw9606	rigid:V+wepSJLpYLrWGLPO3TcVyK+IyM	false	ha tag:n-n|mutation with no effect:191-191	myc tag:n-n	-	-	psi-mi:"MI:1200"(immunocytochemistry)	psi-mi:"MI:1200"(immunocytochemistry)