#ID(s) interactor A ID(s) interactor B Alt. ID(s) interactor A Alt. ID(s) interactor B Alias(es) interactor A Alias(es) interactor B Interaction detection method(s) Publication 1st author(s) Publication Identifier(s) Taxid interactor A Taxid interactor B Interaction type(s) Source database(s) Interaction identifier(s) Confidence value(s) Expansion method(s) Biological role(s) interactor A Biological role(s) interactor B Experimental role(s) interactor A Experimental role(s) interactor B Type(s) interactor A Type(s) interactor B Xref(s) interactor A Xref(s) interactor B Interaction Xref(s) Annotation(s) interactor A Annotation(s) interactor B Interaction annotation(s) Host organism(s) Interaction parameter(s) Creation date Update date Checksum(s) interactor A Checksum(s) interactor B Interaction Checksum(s) Negative Feature(s) interactor A Feature(s) interactor B Stoichiometry(s) interactor A Stoichiometry(s) interactor B Identification method participant A Identification method participant B uniprotkb:P59596 uniprotkb:P59596 intact:EBI-25487824|uniprotkb:Q6S8E5|uniprotkb:Q7T6Q8|uniprotkb:Q7T6R1|uniprotkb:Q7T6R5|uniprotkb:Q7T6S0|uniprotkb:Q7T6S3|uniprotkb:Q7T726|uniprotkb:Q7T7P6|uniprotkb:Q7T7S6|uniprotkb:Q7TA12 intact:EBI-25487824|uniprotkb:Q6S8E5|uniprotkb:Q7T6Q8|uniprotkb:Q7T6R1|uniprotkb:Q7T6R5|uniprotkb:Q7T6S0|uniprotkb:Q7T6S3|uniprotkb:Q7T726|uniprotkb:Q7T7P6|uniprotkb:Q7T7S6|uniprotkb:Q7TA12 psi-mi:vme1_sars(display_long)|uniprotkb:M(gene name)|psi-mi:M(display_short)|uniprotkb:E1 glycoprotein(gene name synonym)|uniprotkb:Matrix glycoprotein(gene name synonym)|uniprotkb:Membrane glycoprotein(gene name synonym)|uniprotkb:5(orf name) psi-mi:vme1_sars(display_long)|uniprotkb:M(gene name)|psi-mi:M(display_short)|uniprotkb:E1 glycoprotein(gene name synonym)|uniprotkb:Matrix glycoprotein(gene name synonym)|uniprotkb:Membrane glycoprotein(gene name synonym)|uniprotkb:5(orf name) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Tseng et al. (2012) pubmed:23700447|imex:IM-28052 taxid:694009(sars-cov)|taxid:694009(Human SARS coronavirus) taxid:694009(sars-cov)|taxid:694009(Human SARS coronavirus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0465"(DIP) intact:EBI-25639766|imex:IM-28052-1 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0005788"(endoplasmic reticulum lumen)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0019031"(viral envelope)|go:"GO:0030666"(endocytic vesicle membrane)|go:"GO:0030683"(mitigation of host immune response by virus)|go:"GO:0033116"(endoplasmic reticulum-Golgi intermediate compartment membrane)|go:"GO:0039660"(structural constituent of virion)|go:"GO:0042802"(identical protein binding)|go:"GO:0044178"(host cell Golgi membrane)|go:"GO:0055036"(virion membrane)|interpro:IPR044361|rcsb pdb:3I6G|interpro:IPR002574(Coronavirus M matrix/glycoprotein)|rcsb pdb:3I6K|rcsb pdb:3TO2|reactome:R-HSA-9678110|reactome:R-HSA-9679509|reactome:R-HSA-9683612|reactome:R-HSA-9683701|refseq:NP_828855.1 go:"GO:0005788"(endoplasmic reticulum lumen)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0019031"(viral envelope)|go:"GO:0030666"(endocytic vesicle membrane)|go:"GO:0030683"(mitigation of host immune response by virus)|go:"GO:0033116"(endoplasmic reticulum-Golgi intermediate compartment membrane)|go:"GO:0039660"(structural constituent of virion)|go:"GO:0042802"(identical protein binding)|go:"GO:0044178"(host cell Golgi membrane)|go:"GO:0055036"(virion membrane)|interpro:IPR044361|rcsb pdb:3I6G|interpro:IPR002574(Coronavirus M matrix/glycoprotein)|rcsb pdb:3I6K|rcsb pdb:3TO2|reactome:R-HSA-9678110|reactome:R-HSA-9679509|reactome:R-HSA-9683612|reactome:R-HSA-9683701|refseq:NP_828855.1 - - - figure legend:Fig 4b|dataset:Virus - Publications including interactions involving viral proteins|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/06/06 2020/06/06 rogid:OmfDgTLjYrCAvTbWQWd78WAlrEI694009 rogid:OmfDgTLjYrCAvTbWQWd78WAlrEI694009 rigid:2Zf2RS5pzrbUCbqerjo10RGNWcI false mutation with no effect:19-19|flag tag:c-c mutation with no effect:19-19 - - psi-mi:"MI:0396"(predetermined participant)|psi-mi:"MI:0705"(anti tag western blot) psi-mi:"MI:0396"(predetermined participant)|psi-mi:"MI:0113"(western blot) uniprotkb:P59596 uniprotkb:P59596 intact:EBI-25487824|uniprotkb:Q6S8E5|uniprotkb:Q7T6Q8|uniprotkb:Q7T6R1|uniprotkb:Q7T6R5|uniprotkb:Q7T6S0|uniprotkb:Q7T6S3|uniprotkb:Q7T726|uniprotkb:Q7T7P6|uniprotkb:Q7T7S6|uniprotkb:Q7TA12 intact:EBI-25487824|uniprotkb:Q6S8E5|uniprotkb:Q7T6Q8|uniprotkb:Q7T6R1|uniprotkb:Q7T6R5|uniprotkb:Q7T6S0|uniprotkb:Q7T6S3|uniprotkb:Q7T726|uniprotkb:Q7T7P6|uniprotkb:Q7T7S6|uniprotkb:Q7TA12 psi-mi:vme1_sars(display_long)|uniprotkb:M(gene name)|psi-mi:M(display_short)|uniprotkb:E1 glycoprotein(gene name synonym)|uniprotkb:Matrix glycoprotein(gene name synonym)|uniprotkb:Membrane glycoprotein(gene name synonym)|uniprotkb:5(orf name) psi-mi:vme1_sars(display_long)|uniprotkb:M(gene name)|psi-mi:M(display_short)|uniprotkb:E1 glycoprotein(gene name synonym)|uniprotkb:Matrix glycoprotein(gene name synonym)|uniprotkb:Membrane glycoprotein(gene name synonym)|uniprotkb:5(orf name) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Tseng et al. (2012) pubmed:23700447|imex:IM-28052 taxid:694009(sars-cov)|taxid:694009(Human SARS coronavirus) taxid:694009(sars-cov)|taxid:694009(Human SARS coronavirus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0465"(DIP) intact:EBI-25639775|imex:IM-28052-3 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0005788"(endoplasmic reticulum lumen)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0019031"(viral envelope)|go:"GO:0030666"(endocytic vesicle membrane)|go:"GO:0030683"(mitigation of host immune response by virus)|go:"GO:0033116"(endoplasmic reticulum-Golgi intermediate compartment membrane)|go:"GO:0039660"(structural constituent of virion)|go:"GO:0042802"(identical protein binding)|go:"GO:0044178"(host cell Golgi membrane)|go:"GO:0055036"(virion membrane)|interpro:IPR044361|rcsb pdb:3I6G|interpro:IPR002574(Coronavirus M matrix/glycoprotein)|rcsb pdb:3I6K|rcsb pdb:3TO2|reactome:R-HSA-9678110|reactome:R-HSA-9679509|reactome:R-HSA-9683612|reactome:R-HSA-9683701|refseq:NP_828855.1 go:"GO:0005788"(endoplasmic reticulum lumen)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0019031"(viral envelope)|go:"GO:0030666"(endocytic vesicle membrane)|go:"GO:0030683"(mitigation of host immune response by virus)|go:"GO:0033116"(endoplasmic reticulum-Golgi intermediate compartment membrane)|go:"GO:0039660"(structural constituent of virion)|go:"GO:0042802"(identical protein binding)|go:"GO:0044178"(host cell Golgi membrane)|go:"GO:0055036"(virion membrane)|interpro:IPR044361|rcsb pdb:3I6G|interpro:IPR002574(Coronavirus M matrix/glycoprotein)|rcsb pdb:3I6K|rcsb pdb:3TO2|reactome:R-HSA-9678110|reactome:R-HSA-9679509|reactome:R-HSA-9683612|reactome:R-HSA-9683701|refseq:NP_828855.1 - - - figure legend:Fig 4b|dataset:Virus - Publications including interactions involving viral proteins|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/06/06 2020/06/06 rogid:OmfDgTLjYrCAvTbWQWd78WAlrEI694009 rogid:OmfDgTLjYrCAvTbWQWd78WAlrEI694009 rigid:2Zf2RS5pzrbUCbqerjo10RGNWcI false mutation with no effect:91-91|flag tag:c-c mutation with no effect:91-91 - - psi-mi:"MI:0396"(predetermined participant)|psi-mi:"MI:0705"(anti tag western blot) psi-mi:"MI:0396"(predetermined participant)|psi-mi:"MI:0113"(western blot) uniprotkb:P59596 uniprotkb:P59596 intact:EBI-25487824|uniprotkb:Q6S8E5|uniprotkb:Q7T6Q8|uniprotkb:Q7T6R1|uniprotkb:Q7T6R5|uniprotkb:Q7T6S0|uniprotkb:Q7T6S3|uniprotkb:Q7T726|uniprotkb:Q7T7P6|uniprotkb:Q7T7S6|uniprotkb:Q7TA12 intact:EBI-25487824|uniprotkb:Q6S8E5|uniprotkb:Q7T6Q8|uniprotkb:Q7T6R1|uniprotkb:Q7T6R5|uniprotkb:Q7T6S0|uniprotkb:Q7T6S3|uniprotkb:Q7T726|uniprotkb:Q7T7P6|uniprotkb:Q7T7S6|uniprotkb:Q7TA12 psi-mi:vme1_sars(display_long)|uniprotkb:M(gene name)|psi-mi:M(display_short)|uniprotkb:E1 glycoprotein(gene name synonym)|uniprotkb:Matrix glycoprotein(gene name synonym)|uniprotkb:Membrane glycoprotein(gene name synonym)|uniprotkb:5(orf name) psi-mi:vme1_sars(display_long)|uniprotkb:M(gene name)|psi-mi:M(display_short)|uniprotkb:E1 glycoprotein(gene name synonym)|uniprotkb:Matrix glycoprotein(gene name synonym)|uniprotkb:Membrane glycoprotein(gene name synonym)|uniprotkb:5(orf name) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Tseng et al. (2012) pubmed:23700447|imex:IM-28052 taxid:694009(sars-cov)|taxid:694009(Human SARS coronavirus) taxid:694009(sars-cov)|taxid:694009(Human SARS coronavirus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0465"(DIP) intact:EBI-25639784|imex:IM-28052-21 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0005788"(endoplasmic reticulum lumen)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0019031"(viral envelope)|go:"GO:0030666"(endocytic vesicle membrane)|go:"GO:0030683"(mitigation of host immune response by virus)|go:"GO:0033116"(endoplasmic reticulum-Golgi intermediate compartment membrane)|go:"GO:0039660"(structural constituent of virion)|go:"GO:0042802"(identical protein binding)|go:"GO:0044178"(host cell Golgi membrane)|go:"GO:0055036"(virion membrane)|interpro:IPR044361|rcsb pdb:3I6G|interpro:IPR002574(Coronavirus M matrix/glycoprotein)|rcsb pdb:3I6K|rcsb pdb:3TO2|reactome:R-HSA-9678110|reactome:R-HSA-9679509|reactome:R-HSA-9683612|reactome:R-HSA-9683701|refseq:NP_828855.1 go:"GO:0005788"(endoplasmic reticulum lumen)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0019031"(viral envelope)|go:"GO:0030666"(endocytic vesicle membrane)|go:"GO:0030683"(mitigation of host immune response by virus)|go:"GO:0033116"(endoplasmic reticulum-Golgi intermediate compartment membrane)|go:"GO:0039660"(structural constituent of virion)|go:"GO:0042802"(identical protein binding)|go:"GO:0044178"(host cell Golgi membrane)|go:"GO:0055036"(virion membrane)|interpro:IPR044361|rcsb pdb:3I6G|interpro:IPR002574(Coronavirus M matrix/glycoprotein)|rcsb pdb:3I6K|rcsb pdb:3TO2|reactome:R-HSA-9678110|reactome:R-HSA-9679509|reactome:R-HSA-9683612|reactome:R-HSA-9683701|refseq:NP_828855.1 - - - figure legend:Fig 4b|dataset:Virus - Publications including interactions involving viral proteins|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/06/06 2020/06/06 rogid:OmfDgTLjYrCAvTbWQWd78WAlrEI694009 rogid:OmfDgTLjYrCAvTbWQWd78WAlrEI694009 rigid:2Zf2RS5pzrbUCbqerjo10RGNWcI false mutation with no effect:94-94|flag tag:c-c mutation with no effect:94-94 - - psi-mi:"MI:0396"(predetermined participant)|psi-mi:"MI:0705"(anti tag western blot) psi-mi:"MI:0396"(predetermined participant)|psi-mi:"MI:0113"(western blot) uniprotkb:P59596 uniprotkb:P59596 intact:EBI-25487824|uniprotkb:Q6S8E5|uniprotkb:Q7T6Q8|uniprotkb:Q7T6R1|uniprotkb:Q7T6R5|uniprotkb:Q7T6S0|uniprotkb:Q7T6S3|uniprotkb:Q7T726|uniprotkb:Q7T7P6|uniprotkb:Q7T7S6|uniprotkb:Q7TA12 intact:EBI-25487824|uniprotkb:Q6S8E5|uniprotkb:Q7T6Q8|uniprotkb:Q7T6R1|uniprotkb:Q7T6R5|uniprotkb:Q7T6S0|uniprotkb:Q7T6S3|uniprotkb:Q7T726|uniprotkb:Q7T7P6|uniprotkb:Q7T7S6|uniprotkb:Q7TA12 psi-mi:vme1_sars(display_long)|uniprotkb:M(gene name)|psi-mi:M(display_short)|uniprotkb:E1 glycoprotein(gene name synonym)|uniprotkb:Matrix glycoprotein(gene name synonym)|uniprotkb:Membrane glycoprotein(gene name synonym)|uniprotkb:5(orf name) psi-mi:vme1_sars(display_long)|uniprotkb:M(gene name)|psi-mi:M(display_short)|uniprotkb:E1 glycoprotein(gene name synonym)|uniprotkb:Matrix glycoprotein(gene name synonym)|uniprotkb:Membrane glycoprotein(gene name synonym)|uniprotkb:5(orf name) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Tseng et al. (2012) pubmed:23700447|imex:IM-28052 taxid:694009(sars-cov)|taxid:694009(Human SARS coronavirus) taxid:694009(sars-cov)|taxid:694009(Human SARS coronavirus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0465"(DIP) intact:EBI-25639792|imex:IM-28052-5 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0005788"(endoplasmic reticulum lumen)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0019031"(viral envelope)|go:"GO:0030666"(endocytic vesicle membrane)|go:"GO:0030683"(mitigation of host immune response by virus)|go:"GO:0033116"(endoplasmic reticulum-Golgi intermediate compartment membrane)|go:"GO:0039660"(structural constituent of virion)|go:"GO:0042802"(identical protein binding)|go:"GO:0044178"(host cell Golgi membrane)|go:"GO:0055036"(virion membrane)|interpro:IPR044361|rcsb pdb:3I6G|interpro:IPR002574(Coronavirus M matrix/glycoprotein)|rcsb pdb:3I6K|rcsb pdb:3TO2|reactome:R-HSA-9678110|reactome:R-HSA-9679509|reactome:R-HSA-9683612|reactome:R-HSA-9683701|refseq:NP_828855.1 go:"GO:0005788"(endoplasmic reticulum lumen)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0019031"(viral envelope)|go:"GO:0030666"(endocytic vesicle membrane)|go:"GO:0030683"(mitigation of host immune response by virus)|go:"GO:0033116"(endoplasmic reticulum-Golgi intermediate compartment membrane)|go:"GO:0039660"(structural constituent of virion)|go:"GO:0042802"(identical protein binding)|go:"GO:0044178"(host cell Golgi membrane)|go:"GO:0055036"(virion membrane)|interpro:IPR044361|rcsb pdb:3I6G|interpro:IPR002574(Coronavirus M matrix/glycoprotein)|rcsb pdb:3I6K|rcsb pdb:3TO2|reactome:R-HSA-9678110|reactome:R-HSA-9679509|reactome:R-HSA-9683612|reactome:R-HSA-9683701|refseq:NP_828855.1 - - - figure legend:Fig 4b|dataset:Virus - Publications including interactions involving viral proteins|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/06/06 2020/06/06 rogid:OmfDgTLjYrCAvTbWQWd78WAlrEI694009 rogid:OmfDgTLjYrCAvTbWQWd78WAlrEI694009 rigid:2Zf2RS5pzrbUCbqerjo10RGNWcI false mutation with no effect:95-95|flag tag:c-c mutation with no effect:95-95 - - psi-mi:"MI:0396"(predetermined participant)|psi-mi:"MI:0705"(anti tag western blot) psi-mi:"MI:0396"(predetermined participant)|psi-mi:"MI:0113"(western blot) uniprotkb:P59595 uniprotkb:P59596 intact:EBI-7602718|uniprotkb:Q80E50|uniprotkb:Q7T3Z4|uniprotkb:Q7TF99|uniprotkb:Q7TA14|intact:MINT-1346173 intact:EBI-25487824|uniprotkb:Q6S8E5|uniprotkb:Q7T6Q8|uniprotkb:Q7T6R1|uniprotkb:Q7T6R5|uniprotkb:Q7T6S0|uniprotkb:Q7T6S3|uniprotkb:Q7T726|uniprotkb:Q7T7P6|uniprotkb:Q7T7S6|uniprotkb:Q7TA12 psi-mi:ncap_sars(display_long)|uniprotkb:N(gene name)|psi-mi:N(display_short)|uniprotkb:9a(orf name)|uniprotkb:Nucleocapsid protein(gene name synonym) psi-mi:vme1_sars(display_long)|uniprotkb:M(gene name)|psi-mi:M(display_short)|uniprotkb:E1 glycoprotein(gene name synonym)|uniprotkb:Matrix glycoprotein(gene name synonym)|uniprotkb:Membrane glycoprotein(gene name synonym)|uniprotkb:5(orf name) psi-mi:"MI:0096"(pull down) Tseng et al. (2012) pubmed:23700447|imex:IM-28052 taxid:694009(sars-cov)|taxid:694009(Human SARS coronavirus) taxid:694009(sars-cov)|taxid:694009(Human SARS coronavirus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0465"(DIP) intact:EBI-25639815|imex:IM-28052-7 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR001218(Coronavirus nucleocapsid protein)|interpro:IPR044344|interpro:IPR044345|rcsb pdb:2OFZ|rcsb pdb:2OG3|rcsb pdb:2GIB|rcsb pdb:3I6L|rcsb pdb:1X7Q|rcsb pdb:2CJR|rcsb pdb:2JW8|rcsb pdb:1SSK|go:"GO:0003723"(RNA binding)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0019013"(viral nucleocapsid)|go:"GO:0019028"(viral capsid)|go:"GO:0033116"(endoplasmic reticulum-Golgi intermediate compartment membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0044172"(host cell endoplasmic reticulum-Golgi intermediate compartment)|go:"GO:0044177"(host cell Golgi apparatus)|go:"GO:0044220"(host cell perinuclear region of cytoplasm)|rcsb pdb:6IEX|interpro:IPR037179|interpro:IPR037195|interpro:IPR043505|reactome:R-HSA-9678110|reactome:R-HSA-9679509|reactome:R-HSA-9682706|reactome:R-HSA-9682708|reactome:R-HSA-9683610|reactome:R-HSA-9683701|refseq:NP_828858.1|rcsb pdb:7LG0 go:"GO:0005788"(endoplasmic reticulum lumen)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0019031"(viral envelope)|go:"GO:0030666"(endocytic vesicle membrane)|go:"GO:0030683"(mitigation of host immune response by virus)|go:"GO:0033116"(endoplasmic reticulum-Golgi intermediate compartment membrane)|go:"GO:0039660"(structural constituent of virion)|go:"GO:0042802"(identical protein binding)|go:"GO:0044178"(host cell Golgi membrane)|go:"GO:0055036"(virion membrane)|interpro:IPR044361|rcsb pdb:3I6G|interpro:IPR002574(Coronavirus M matrix/glycoprotein)|rcsb pdb:3I6K|rcsb pdb:3TO2|reactome:R-HSA-9678110|reactome:R-HSA-9679509|reactome:R-HSA-9683612|reactome:R-HSA-9683701|refseq:NP_828855.1 - comment:mint|function:Major structural component of virions that associates with genomic RNA to form a long, flexible, helical nucleocapsid - figure legend:Fig 6a, Fig 6b|dataset:Virus - Publications including interactions involving viral proteins|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/06/06 2020/06/06 rogid:WRVYCgOuKU7HjOnwEjqwCixyjOg694009 rogid:OmfDgTLjYrCAvTbWQWd78WAlrEI694009 rigid:/RnU6RYIvm2biNZJ24rdlnOyvE0 false glutathione s tranferase tag:n-n mutation with no effect:19-19|mutation with no effect:91-91|mutation with no effect:94-94|mutation with no effect:95-95|mutation with no effect:95-95|mutation with no effect:218-219 - - psi-mi:"MI:0396"(predetermined participant)|psi-mi:"MI:0705"(anti tag western blot) psi-mi:"MI:0396"(predetermined participant)|psi-mi:"MI:0113"(western blot) uniprotkb:P59595 uniprotkb:P59595 intact:EBI-7602718|uniprotkb:Q80E50|uniprotkb:Q7T3Z4|uniprotkb:Q7TF99|uniprotkb:Q7TA14|intact:MINT-1346173 intact:EBI-7602718|uniprotkb:Q80E50|uniprotkb:Q7T3Z4|uniprotkb:Q7TF99|uniprotkb:Q7TA14|intact:MINT-1346173 psi-mi:ncap_sars(display_long)|uniprotkb:N(gene name)|psi-mi:N(display_short)|uniprotkb:9a(orf name)|uniprotkb:Nucleocapsid protein(gene name synonym) psi-mi:ncap_sars(display_long)|uniprotkb:N(gene name)|psi-mi:N(display_short)|uniprotkb:9a(orf name)|uniprotkb:Nucleocapsid protein(gene name synonym) psi-mi:"MI:0096"(pull down) Tseng et al. (2012) pubmed:23700447|imex:IM-28052 taxid:694009(sars-cov)|taxid:694009(Human SARS coronavirus) taxid:694009(sars-cov)|taxid:694009(Human SARS coronavirus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0465"(DIP) intact:EBI-25639825|imex:IM-28052-9 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR001218(Coronavirus nucleocapsid protein)|interpro:IPR044344|interpro:IPR044345|rcsb pdb:2OFZ|rcsb pdb:2OG3|rcsb pdb:2GIB|rcsb pdb:3I6L|rcsb pdb:1X7Q|rcsb pdb:2CJR|rcsb pdb:2JW8|rcsb pdb:1SSK|go:"GO:0003723"(RNA binding)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0019013"(viral nucleocapsid)|go:"GO:0019028"(viral capsid)|go:"GO:0033116"(endoplasmic reticulum-Golgi intermediate compartment membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0044172"(host cell endoplasmic reticulum-Golgi intermediate compartment)|go:"GO:0044177"(host cell Golgi apparatus)|go:"GO:0044220"(host cell perinuclear region of cytoplasm)|rcsb pdb:6IEX|interpro:IPR037179|interpro:IPR037195|interpro:IPR043505|reactome:R-HSA-9678110|reactome:R-HSA-9679509|reactome:R-HSA-9682706|reactome:R-HSA-9682708|reactome:R-HSA-9683610|reactome:R-HSA-9683701|refseq:NP_828858.1|rcsb pdb:7LG0 interpro:IPR001218(Coronavirus nucleocapsid protein)|interpro:IPR044344|interpro:IPR044345|rcsb pdb:2OFZ|rcsb pdb:2OG3|rcsb pdb:2GIB|rcsb pdb:3I6L|rcsb pdb:1X7Q|rcsb pdb:2CJR|rcsb pdb:2JW8|rcsb pdb:1SSK|go:"GO:0003723"(RNA binding)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0019013"(viral nucleocapsid)|go:"GO:0019028"(viral capsid)|go:"GO:0033116"(endoplasmic reticulum-Golgi intermediate compartment membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0044172"(host cell endoplasmic reticulum-Golgi intermediate compartment)|go:"GO:0044177"(host cell Golgi apparatus)|go:"GO:0044220"(host cell perinuclear region of cytoplasm)|rcsb pdb:6IEX|interpro:IPR037179|interpro:IPR037195|interpro:IPR043505|reactome:R-HSA-9678110|reactome:R-HSA-9679509|reactome:R-HSA-9682706|reactome:R-HSA-9682708|reactome:R-HSA-9683610|reactome:R-HSA-9683701|refseq:NP_828858.1|rcsb pdb:7LG0 - comment:mint|function:Major structural component of virions that associates with genomic RNA to form a long, flexible, helical nucleocapsid comment:mint|function:Major structural component of virions that associates with genomic RNA to form a long, flexible, helical nucleocapsid figure legend:Fig 6a|dataset:Virus - Publications including interactions involving viral proteins|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/06/06 2020/06/06 rogid:WRVYCgOuKU7HjOnwEjqwCixyjOg694009 rogid:WRVYCgOuKU7HjOnwEjqwCixyjOg694009 rigid:nfUtR/Mag3BPyE3iFX33w2BEkZs false - glutathione s tranferase tag:n-n - - psi-mi:"MI:0396"(predetermined participant)|psi-mi:"MI:0113"(western blot) psi-mi:"MI:0396"(predetermined participant)|psi-mi:"MI:0705"(anti tag western blot) uniprotkb:P59595 uniprotkb:P59596 intact:EBI-7602718|uniprotkb:Q80E50|uniprotkb:Q7T3Z4|uniprotkb:Q7TF99|uniprotkb:Q7TA14|intact:MINT-1346173 intact:EBI-25487824|uniprotkb:Q6S8E5|uniprotkb:Q7T6Q8|uniprotkb:Q7T6R1|uniprotkb:Q7T6R5|uniprotkb:Q7T6S0|uniprotkb:Q7T6S3|uniprotkb:Q7T726|uniprotkb:Q7T7P6|uniprotkb:Q7T7S6|uniprotkb:Q7TA12 psi-mi:ncap_sars(display_long)|uniprotkb:N(gene name)|psi-mi:N(display_short)|uniprotkb:9a(orf name)|uniprotkb:Nucleocapsid protein(gene name synonym) psi-mi:vme1_sars(display_long)|uniprotkb:M(gene name)|psi-mi:M(display_short)|uniprotkb:E1 glycoprotein(gene name synonym)|uniprotkb:Matrix glycoprotein(gene name synonym)|uniprotkb:Membrane glycoprotein(gene name synonym)|uniprotkb:5(orf name) psi-mi:"MI:0096"(pull down) Tseng et al. (2012) pubmed:23700447|imex:IM-28052 taxid:694009(sars-cov)|taxid:694009(Human SARS coronavirus) taxid:694009(sars-cov)|taxid:694009(Human SARS coronavirus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0465"(DIP) intact:EBI-25639839|imex:IM-28052-11 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR001218(Coronavirus nucleocapsid protein)|interpro:IPR044344|interpro:IPR044345|rcsb pdb:2OFZ|rcsb pdb:2OG3|rcsb pdb:2GIB|rcsb pdb:3I6L|rcsb pdb:1X7Q|rcsb pdb:2CJR|rcsb pdb:2JW8|rcsb pdb:1SSK|go:"GO:0003723"(RNA binding)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0019013"(viral nucleocapsid)|go:"GO:0019028"(viral capsid)|go:"GO:0033116"(endoplasmic reticulum-Golgi intermediate compartment membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0044172"(host cell endoplasmic reticulum-Golgi intermediate compartment)|go:"GO:0044177"(host cell Golgi apparatus)|go:"GO:0044220"(host cell perinuclear region of cytoplasm)|rcsb pdb:6IEX|interpro:IPR037179|interpro:IPR037195|interpro:IPR043505|reactome:R-HSA-9678110|reactome:R-HSA-9679509|reactome:R-HSA-9682706|reactome:R-HSA-9682708|reactome:R-HSA-9683610|reactome:R-HSA-9683701|refseq:NP_828858.1|rcsb pdb:7LG0 go:"GO:0005788"(endoplasmic reticulum lumen)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0019031"(viral envelope)|go:"GO:0030666"(endocytic vesicle membrane)|go:"GO:0030683"(mitigation of host immune response by virus)|go:"GO:0033116"(endoplasmic reticulum-Golgi intermediate compartment membrane)|go:"GO:0039660"(structural constituent of virion)|go:"GO:0042802"(identical protein binding)|go:"GO:0044178"(host cell Golgi membrane)|go:"GO:0055036"(virion membrane)|interpro:IPR044361|rcsb pdb:3I6G|interpro:IPR002574(Coronavirus M matrix/glycoprotein)|rcsb pdb:3I6K|rcsb pdb:3TO2|reactome:R-HSA-9678110|reactome:R-HSA-9679509|reactome:R-HSA-9683612|reactome:R-HSA-9683701|refseq:NP_828855.1 - comment:mint|function:Major structural component of virions that associates with genomic RNA to form a long, flexible, helical nucleocapsid - figure legend:Fig 6c|dataset:Virus - Publications including interactions involving viral proteins|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/06/06 2020/06/06 rogid:WRVYCgOuKU7HjOnwEjqwCixyjOg694009 rogid:OmfDgTLjYrCAvTbWQWd78WAlrEI694009 rigid:/RnU6RYIvm2biNZJ24rdlnOyvE0 false glutathione s tranferase tag:n-n mutation disrupting interaction:158-158 - - psi-mi:"MI:0396"(predetermined participant)|psi-mi:"MI:0705"(anti tag western blot) psi-mi:"MI:0396"(predetermined participant)|psi-mi:"MI:0113"(western blot) uniprotkb:P59595 uniprotkb:P59596 intact:EBI-7602718|uniprotkb:Q80E50|uniprotkb:Q7T3Z4|uniprotkb:Q7TF99|uniprotkb:Q7TA14|intact:MINT-1346173 intact:EBI-25487824|uniprotkb:Q6S8E5|uniprotkb:Q7T6Q8|uniprotkb:Q7T6R1|uniprotkb:Q7T6R5|uniprotkb:Q7T6S0|uniprotkb:Q7T6S3|uniprotkb:Q7T726|uniprotkb:Q7T7P6|uniprotkb:Q7T7S6|uniprotkb:Q7TA12 psi-mi:ncap_sars(display_long)|uniprotkb:N(gene name)|psi-mi:N(display_short)|uniprotkb:9a(orf name)|uniprotkb:Nucleocapsid protein(gene name synonym) psi-mi:vme1_sars(display_long)|uniprotkb:M(gene name)|psi-mi:M(display_short)|uniprotkb:E1 glycoprotein(gene name synonym)|uniprotkb:Matrix glycoprotein(gene name synonym)|uniprotkb:Membrane glycoprotein(gene name synonym)|uniprotkb:5(orf name) psi-mi:"MI:0096"(pull down) Tseng et al. (2012) pubmed:23700447|imex:IM-28052 taxid:694009(sars-cov)|taxid:694009(Human SARS coronavirus) taxid:694009(sars-cov)|taxid:694009(Human SARS coronavirus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0465"(DIP) intact:EBI-25639857|imex:IM-28052-13 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR001218(Coronavirus nucleocapsid protein)|interpro:IPR044344|interpro:IPR044345|rcsb pdb:2OFZ|rcsb pdb:2OG3|rcsb pdb:2GIB|rcsb pdb:3I6L|rcsb pdb:1X7Q|rcsb pdb:2CJR|rcsb pdb:2JW8|rcsb pdb:1SSK|go:"GO:0003723"(RNA binding)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0019013"(viral nucleocapsid)|go:"GO:0019028"(viral capsid)|go:"GO:0033116"(endoplasmic reticulum-Golgi intermediate compartment membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0044172"(host cell endoplasmic reticulum-Golgi intermediate compartment)|go:"GO:0044177"(host cell Golgi apparatus)|go:"GO:0044220"(host cell perinuclear region of cytoplasm)|rcsb pdb:6IEX|interpro:IPR037179|interpro:IPR037195|interpro:IPR043505|reactome:R-HSA-9678110|reactome:R-HSA-9679509|reactome:R-HSA-9682706|reactome:R-HSA-9682708|reactome:R-HSA-9683610|reactome:R-HSA-9683701|refseq:NP_828858.1|rcsb pdb:7LG0 go:"GO:0005788"(endoplasmic reticulum lumen)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0019031"(viral envelope)|go:"GO:0030666"(endocytic vesicle membrane)|go:"GO:0030683"(mitigation of host immune response by virus)|go:"GO:0033116"(endoplasmic reticulum-Golgi intermediate compartment membrane)|go:"GO:0039660"(structural constituent of virion)|go:"GO:0042802"(identical protein binding)|go:"GO:0044178"(host cell Golgi membrane)|go:"GO:0055036"(virion membrane)|interpro:IPR044361|rcsb pdb:3I6G|interpro:IPR002574(Coronavirus M matrix/glycoprotein)|rcsb pdb:3I6K|rcsb pdb:3TO2|reactome:R-HSA-9678110|reactome:R-HSA-9679509|reactome:R-HSA-9683612|reactome:R-HSA-9683701|refseq:NP_828855.1 - comment:mint|function:Major structural component of virions that associates with genomic RNA to form a long, flexible, helical nucleocapsid - figure legend:Fig 6c|dataset:Virus - Publications including interactions involving viral proteins|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/06/06 2020/06/06 rogid:WRVYCgOuKU7HjOnwEjqwCixyjOg694009 rogid:OmfDgTLjYrCAvTbWQWd78WAlrEI694009 rigid:/RnU6RYIvm2biNZJ24rdlnOyvE0 false glutathione s tranferase tag:n-n flag tag:c-c - - psi-mi:"MI:0396"(predetermined participant)|psi-mi:"MI:0705"(anti tag western blot) psi-mi:"MI:0396"(predetermined participant)|psi-mi:"MI:0113"(western blot) uniprotkb:P59595 uniprotkb:P59596 intact:EBI-7602718|uniprotkb:Q80E50|uniprotkb:Q7T3Z4|uniprotkb:Q7TF99|uniprotkb:Q7TA14|intact:MINT-1346173 intact:EBI-25487824|uniprotkb:Q6S8E5|uniprotkb:Q7T6Q8|uniprotkb:Q7T6R1|uniprotkb:Q7T6R5|uniprotkb:Q7T6S0|uniprotkb:Q7T6S3|uniprotkb:Q7T726|uniprotkb:Q7T7P6|uniprotkb:Q7T7S6|uniprotkb:Q7TA12 psi-mi:ncap_sars(display_long)|uniprotkb:N(gene name)|psi-mi:N(display_short)|uniprotkb:9a(orf name)|uniprotkb:Nucleocapsid protein(gene name synonym) psi-mi:vme1_sars(display_long)|uniprotkb:M(gene name)|psi-mi:M(display_short)|uniprotkb:E1 glycoprotein(gene name synonym)|uniprotkb:Matrix glycoprotein(gene name synonym)|uniprotkb:Membrane glycoprotein(gene name synonym)|uniprotkb:5(orf name) psi-mi:"MI:0019"(coimmunoprecipitation) Tseng et al. (2012) pubmed:23700447|imex:IM-28052 taxid:694009(sars-cov)|taxid:694009(Human SARS coronavirus) taxid:694009(sars-cov)|taxid:694009(Human SARS coronavirus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0465"(DIP) intact:EBI-25639874|imex:IM-28052-15 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR001218(Coronavirus nucleocapsid protein)|interpro:IPR044344|interpro:IPR044345|rcsb pdb:2OFZ|rcsb pdb:2OG3|rcsb pdb:2GIB|rcsb pdb:3I6L|rcsb pdb:1X7Q|rcsb pdb:2CJR|rcsb pdb:2JW8|rcsb pdb:1SSK|go:"GO:0003723"(RNA binding)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0019013"(viral nucleocapsid)|go:"GO:0019028"(viral capsid)|go:"GO:0033116"(endoplasmic reticulum-Golgi intermediate compartment membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0044172"(host cell endoplasmic reticulum-Golgi intermediate compartment)|go:"GO:0044177"(host cell Golgi apparatus)|go:"GO:0044220"(host cell perinuclear region of cytoplasm)|rcsb pdb:6IEX|interpro:IPR037179|interpro:IPR037195|interpro:IPR043505|reactome:R-HSA-9678110|reactome:R-HSA-9679509|reactome:R-HSA-9682706|reactome:R-HSA-9682708|reactome:R-HSA-9683610|reactome:R-HSA-9683701|refseq:NP_828858.1|rcsb pdb:7LG0 go:"GO:0005788"(endoplasmic reticulum lumen)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0019031"(viral envelope)|go:"GO:0030666"(endocytic vesicle membrane)|go:"GO:0030683"(mitigation of host immune response by virus)|go:"GO:0033116"(endoplasmic reticulum-Golgi intermediate compartment membrane)|go:"GO:0039660"(structural constituent of virion)|go:"GO:0042802"(identical protein binding)|go:"GO:0044178"(host cell Golgi membrane)|go:"GO:0055036"(virion membrane)|interpro:IPR044361|rcsb pdb:3I6G|interpro:IPR002574(Coronavirus M matrix/glycoprotein)|rcsb pdb:3I6K|rcsb pdb:3TO2|reactome:R-HSA-9678110|reactome:R-HSA-9679509|reactome:R-HSA-9683612|reactome:R-HSA-9683701|refseq:NP_828855.1 - comment:mint|function:Major structural component of virions that associates with genomic RNA to form a long, flexible, helical nucleocapsid - figure legend:Fig 6d|dataset:Virus - Publications including interactions involving viral proteins|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/06/06 2020/06/06 rogid:WRVYCgOuKU7HjOnwEjqwCixyjOg694009 rogid:OmfDgTLjYrCAvTbWQWd78WAlrEI694009 rigid:/RnU6RYIvm2biNZJ24rdlnOyvE0 false - mutation with no effect:218-219 - - psi-mi:"MI:0396"(predetermined participant)|psi-mi:"MI:0113"(western blot) psi-mi:"MI:0396"(predetermined participant)|psi-mi:"MI:0113"(western blot) uniprotkb:P59595 uniprotkb:P59596 intact:EBI-7602718|uniprotkb:Q80E50|uniprotkb:Q7T3Z4|uniprotkb:Q7TF99|uniprotkb:Q7TA14|intact:MINT-1346173 intact:EBI-25487824|uniprotkb:Q6S8E5|uniprotkb:Q7T6Q8|uniprotkb:Q7T6R1|uniprotkb:Q7T6R5|uniprotkb:Q7T6S0|uniprotkb:Q7T6S3|uniprotkb:Q7T726|uniprotkb:Q7T7P6|uniprotkb:Q7T7S6|uniprotkb:Q7TA12 psi-mi:ncap_sars(display_long)|uniprotkb:N(gene name)|psi-mi:N(display_short)|uniprotkb:9a(orf name)|uniprotkb:Nucleocapsid protein(gene name synonym) psi-mi:vme1_sars(display_long)|uniprotkb:M(gene name)|psi-mi:M(display_short)|uniprotkb:E1 glycoprotein(gene name synonym)|uniprotkb:Matrix glycoprotein(gene name synonym)|uniprotkb:Membrane glycoprotein(gene name synonym)|uniprotkb:5(orf name) psi-mi:"MI:0019"(coimmunoprecipitation) Tseng et al. (2012) pubmed:23700447|imex:IM-28052 taxid:694009(sars-cov)|taxid:694009(Human SARS coronavirus) taxid:694009(sars-cov)|taxid:694009(Human SARS coronavirus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0465"(DIP) intact:EBI-25639880|imex:IM-28052-17 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR001218(Coronavirus nucleocapsid protein)|interpro:IPR044344|interpro:IPR044345|rcsb pdb:2OFZ|rcsb pdb:2OG3|rcsb pdb:2GIB|rcsb pdb:3I6L|rcsb pdb:1X7Q|rcsb pdb:2CJR|rcsb pdb:2JW8|rcsb pdb:1SSK|go:"GO:0003723"(RNA binding)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0019013"(viral nucleocapsid)|go:"GO:0019028"(viral capsid)|go:"GO:0033116"(endoplasmic reticulum-Golgi intermediate compartment membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0044172"(host cell endoplasmic reticulum-Golgi intermediate compartment)|go:"GO:0044177"(host cell Golgi apparatus)|go:"GO:0044220"(host cell perinuclear region of cytoplasm)|rcsb pdb:6IEX|interpro:IPR037179|interpro:IPR037195|interpro:IPR043505|reactome:R-HSA-9678110|reactome:R-HSA-9679509|reactome:R-HSA-9682706|reactome:R-HSA-9682708|reactome:R-HSA-9683610|reactome:R-HSA-9683701|refseq:NP_828858.1|rcsb pdb:7LG0 go:"GO:0005788"(endoplasmic reticulum lumen)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0019031"(viral envelope)|go:"GO:0030666"(endocytic vesicle membrane)|go:"GO:0030683"(mitigation of host immune response by virus)|go:"GO:0033116"(endoplasmic reticulum-Golgi intermediate compartment membrane)|go:"GO:0039660"(structural constituent of virion)|go:"GO:0042802"(identical protein binding)|go:"GO:0044178"(host cell Golgi membrane)|go:"GO:0055036"(virion membrane)|interpro:IPR044361|rcsb pdb:3I6G|interpro:IPR002574(Coronavirus M matrix/glycoprotein)|rcsb pdb:3I6K|rcsb pdb:3TO2|reactome:R-HSA-9678110|reactome:R-HSA-9679509|reactome:R-HSA-9683612|reactome:R-HSA-9683701|refseq:NP_828855.1 - comment:mint|function:Major structural component of virions that associates with genomic RNA to form a long, flexible, helical nucleocapsid - figure legend:Fig 6d|dataset:Virus - Publications including interactions involving viral proteins|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/06/06 2020/06/06 rogid:WRVYCgOuKU7HjOnwEjqwCixyjOg694009 rogid:OmfDgTLjYrCAvTbWQWd78WAlrEI694009 rigid:/RnU6RYIvm2biNZJ24rdlnOyvE0 false - mutation disrupting interaction:158-158 - - psi-mi:"MI:0396"(predetermined participant)|psi-mi:"MI:0113"(western blot) psi-mi:"MI:0396"(predetermined participant)|psi-mi:"MI:0113"(western blot) uniprotkb:P59595 uniprotkb:P59596 intact:EBI-7602718|uniprotkb:Q80E50|uniprotkb:Q7T3Z4|uniprotkb:Q7TF99|uniprotkb:Q7TA14|intact:MINT-1346173 intact:EBI-25487824|uniprotkb:Q6S8E5|uniprotkb:Q7T6Q8|uniprotkb:Q7T6R1|uniprotkb:Q7T6R5|uniprotkb:Q7T6S0|uniprotkb:Q7T6S3|uniprotkb:Q7T726|uniprotkb:Q7T7P6|uniprotkb:Q7T7S6|uniprotkb:Q7TA12 psi-mi:ncap_sars(display_long)|uniprotkb:N(gene name)|psi-mi:N(display_short)|uniprotkb:9a(orf name)|uniprotkb:Nucleocapsid protein(gene name synonym) psi-mi:vme1_sars(display_long)|uniprotkb:M(gene name)|psi-mi:M(display_short)|uniprotkb:E1 glycoprotein(gene name synonym)|uniprotkb:Matrix glycoprotein(gene name synonym)|uniprotkb:Membrane glycoprotein(gene name synonym)|uniprotkb:5(orf name) psi-mi:"MI:0019"(coimmunoprecipitation) Tseng et al. (2012) pubmed:23700447|imex:IM-28052 taxid:694009(sars-cov)|taxid:694009(Human SARS coronavirus) taxid:694009(sars-cov)|taxid:694009(Human SARS coronavirus) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0465"(DIP) intact:EBI-25639888|imex:IM-28052-19 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR001218(Coronavirus nucleocapsid protein)|interpro:IPR044344|interpro:IPR044345|rcsb pdb:2OFZ|rcsb pdb:2OG3|rcsb pdb:2GIB|rcsb pdb:3I6L|rcsb pdb:1X7Q|rcsb pdb:2CJR|rcsb pdb:2JW8|rcsb pdb:1SSK|go:"GO:0003723"(RNA binding)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0019013"(viral nucleocapsid)|go:"GO:0019028"(viral capsid)|go:"GO:0033116"(endoplasmic reticulum-Golgi intermediate compartment membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0044172"(host cell endoplasmic reticulum-Golgi intermediate compartment)|go:"GO:0044177"(host cell Golgi apparatus)|go:"GO:0044220"(host cell perinuclear region of cytoplasm)|rcsb pdb:6IEX|interpro:IPR037179|interpro:IPR037195|interpro:IPR043505|reactome:R-HSA-9678110|reactome:R-HSA-9679509|reactome:R-HSA-9682706|reactome:R-HSA-9682708|reactome:R-HSA-9683610|reactome:R-HSA-9683701|refseq:NP_828858.1|rcsb pdb:7LG0 go:"GO:0005788"(endoplasmic reticulum lumen)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0019031"(viral envelope)|go:"GO:0030666"(endocytic vesicle membrane)|go:"GO:0030683"(mitigation of host immune response by virus)|go:"GO:0033116"(endoplasmic reticulum-Golgi intermediate compartment membrane)|go:"GO:0039660"(structural constituent of virion)|go:"GO:0042802"(identical protein binding)|go:"GO:0044178"(host cell Golgi membrane)|go:"GO:0055036"(virion membrane)|interpro:IPR044361|rcsb pdb:3I6G|interpro:IPR002574(Coronavirus M matrix/glycoprotein)|rcsb pdb:3I6K|rcsb pdb:3TO2|reactome:R-HSA-9678110|reactome:R-HSA-9679509|reactome:R-HSA-9683612|reactome:R-HSA-9683701|refseq:NP_828855.1 - comment:mint|function:Major structural component of virions that associates with genomic RNA to form a long, flexible, helical nucleocapsid - figure legend:Fig 6d|dataset:Virus - Publications including interactions involving viral proteins|dataset:Coronavirus - Interactions investigated in the context of Coronavirus|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/06/06 2020/06/06 rogid:WRVYCgOuKU7HjOnwEjqwCixyjOg694009 rogid:OmfDgTLjYrCAvTbWQWd78WAlrEI694009 rigid:/RnU6RYIvm2biNZJ24rdlnOyvE0 false - flag tag:c-c - - psi-mi:"MI:0396"(predetermined participant)|psi-mi:"MI:0113"(western blot) psi-mi:"MI:0396"(predetermined participant)|psi-mi:"MI:0113"(western blot)