#ID(s) interactor A ID(s) interactor B Alt. ID(s) interactor A Alt. ID(s) interactor B Alias(es) interactor A Alias(es) interactor B Interaction detection method(s) Publication 1st author(s) Publication Identifier(s) Taxid interactor A Taxid interactor B Interaction type(s) Source database(s) Interaction identifier(s) Confidence value(s) Expansion method(s) Biological role(s) interactor A Biological role(s) interactor B Experimental role(s) interactor A Experimental role(s) interactor B Type(s) interactor A Type(s) interactor B Xref(s) interactor A Xref(s) interactor B Interaction Xref(s) Annotation(s) interactor A Annotation(s) interactor B Interaction annotation(s) Host organism(s) Interaction parameter(s) Creation date Update date Checksum(s) interactor A Checksum(s) interactor B Interaction Checksum(s) Negative Feature(s) interactor A Feature(s) interactor B Stoichiometry(s) interactor A Stoichiometry(s) interactor B Identification method participant A Identification method participant B uniprotkb:P48431 uniprotkb:P41212 intact:EBI-6124081|uniprotkb:Q14537|ensembl:ENSP00000323588 intact:EBI-1372759|uniprotkb:A3QVP6|uniprotkb:Q9UMF6|uniprotkb:Q9UMF7|uniprotkb:Q9UMG0|uniprotkb:A8K076|ensembl:ENSP00000379658 psi-mi:sox2_human(display_long)|uniprotkb:SOX2(gene name)|psi-mi:SOX2(display_short) psi-mi:etv6_human(display_long)|uniprotkb:ETS translocation variant 6(gene name synonym)|uniprotkb:ETS-related protein Tel1(gene name synonym)|uniprotkb:ETV6(gene name)|psi-mi:ETV6(display_short)|uniprotkb:TEL(gene name synonym)|uniprotkb:TEL1(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Cox et al. (2012) pubmed:23667531|imex:IM-28599 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-26574478|imex:IM-28599-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_003097.1|dip:DIP-59913N|ensembl:ENSG00000181449(gene)|ensembl:ENST00000325404(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001649"(osteoblast differentiation)|go:"GO:0001654"(eye development)|go:"GO:0001714"(endodermal cell fate specification)|go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006325"(chromatin organization)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0009611"(response to wounding)|go:"GO:0009653"(anatomical structure morphogenesis)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0021781"(glial cell fate commitment)|go:"GO:0021983"(pituitary gland development)|go:"GO:0021984"(adenohypophysis development)|go:"GO:0022409"(positive regulation of cell-cell adhesion)|go:"GO:0030154"(cell differentiation)|go:"GO:0030900"(forebrain development)|go:"GO:0035019"(somatic stem cell population maintenance)|go:"GO:0035198"(miRNA binding)|go:"GO:0042246"(tissue regeneration)|go:"GO:0043281"(regulation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0043410"(positive regulation of MAPK cascade)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045165"(cell fate commitment)|go:"GO:0045597"(positive regulation of cell differentiation)|go:"GO:0045665"(negative regulation of neuron differentiation)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048839"(inner ear development)|go:"GO:0050680"(negative regulation of epithelial cell proliferation)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0070848"(response to growth factor)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:0097150"(neuronal stem cell population maintenance)|interpro:IPR009071(High mobility group box, HMG)|interpro:IPR022097|interpro:IPR032643|interpro:IPR036910|mint:P48431|rcsb pdb:1O4X|rcsb pdb:2LE4|rcsb pdb:6T7B|rcsb pdb:6T90|rcsb pdb:6WX7|rcsb pdb:6WX8|rcsb pdb:6WX9|rcsb pdb:6YOV|reactome:R-HSA-2892245|reactome:R-HSA-2892247|reactome:R-HSA-3769402|reactome:R-HSA-452723|reactome:R-HSA-6785807|reactome:R-HSA-8986944 refseq:NP_001978.1|dip:DIP-17028N|ensembl:ENSG00000139083(gene)|ensembl:ENST00000396373(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007296"(vitellogenesis)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0022008"(neurogenesis)|go:"GO:0030154"(cell differentiation)|go:"GO:0071425"(hematopoietic stem cell proliferation)|go:"GO:0097152"(mesenchymal cell apoptotic process)|interpro:IPR000418(Ets)|rcsb pdb:5L0P|rcsb pdb:7JU2|rcsb pdb:7N1O|rcsb pdb:7N2B|reactome:R-HSA-9673768|reactome:R-HSA-9703465|interpro:IPR003118(Sterile alpha motif/pointed)|interpro:IPR013761(Sterile alpha motif-type)|interpro:IPR036388|interpro:IPR036390|mint:P41212|rcsb pdb:1JI7|rcsb pdb:1LKY|rcsb pdb:2DAO|rcsb pdb:2QAR|rcsb pdb:2QB0|rcsb pdb:2QB1 go:"GO:0005634"(nucleus) - - figure legend:ST3 F2C|comment:proteins that were enriched in the induced sample more than 6-fold|dataset:Brain Disease - Neurological Diseases & Disorders|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-daoy)|taxid:9606(Homo sapiens DAOY cerebellar medulloblastoma cell line) - 2020/12/29 2020/12/29 rogid:cn8gYfKDpQc8J2ygnqny32sIyyU9606 rogid:ekItHLbEk2Expb+mR7jHa6dPBo89606 rigid:Cnhili6Os5i+9KsmWx3iqclZGC0 false tandem tag:n-n - - - psi-mi:"MI:0658"(multidimensional protein identification technology) psi-mi:"MI:0658"(multidimensional protein identification technology) uniprotkb:P48431 uniprotkb:Q562F6 intact:EBI-6124081|uniprotkb:Q14537|ensembl:ENSP00000323588 intact:EBI-989213|ensembl:ENSP00000350447|uniprotkb:Q53RR9|uniprotkb:Q53T20|uniprotkb:Q86XY4|uniprotkb:Q8IWK2|uniprotkb:Q8IZK1|uniprotkb:Q8N1Q5|uniprotkb:Q96LQ3|intact:EBI-2559582 psi-mi:sox2_human(display_long)|uniprotkb:SOX2(gene name)|psi-mi:SOX2(display_short) psi-mi:sgo2_human(display_long)|uniprotkb:SGO2(gene name)|psi-mi:SGO2(display_short)|uniprotkb:Shugoshin-2(gene name synonym)|uniprotkb:Shugoshin-like 2(gene name synonym)|uniprotkb:Tripin(gene name synonym)|uniprotkb:SGOL2(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Cox et al. (2012) pubmed:23667531|imex:IM-28599 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-26574478|imex:IM-28599-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_003097.1|dip:DIP-59913N|ensembl:ENSG00000181449(gene)|ensembl:ENST00000325404(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001649"(osteoblast differentiation)|go:"GO:0001654"(eye development)|go:"GO:0001714"(endodermal cell fate specification)|go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006325"(chromatin organization)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0009611"(response to wounding)|go:"GO:0009653"(anatomical structure morphogenesis)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0021781"(glial cell fate commitment)|go:"GO:0021983"(pituitary gland development)|go:"GO:0021984"(adenohypophysis development)|go:"GO:0022409"(positive regulation of cell-cell adhesion)|go:"GO:0030154"(cell differentiation)|go:"GO:0030900"(forebrain development)|go:"GO:0035019"(somatic stem cell population maintenance)|go:"GO:0035198"(miRNA binding)|go:"GO:0042246"(tissue regeneration)|go:"GO:0043281"(regulation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0043410"(positive regulation of MAPK cascade)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045165"(cell fate commitment)|go:"GO:0045597"(positive regulation of cell differentiation)|go:"GO:0045665"(negative regulation of neuron differentiation)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048839"(inner ear development)|go:"GO:0050680"(negative regulation of epithelial cell proliferation)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0070848"(response to growth factor)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:0097150"(neuronal stem cell population maintenance)|interpro:IPR009071(High mobility group box, HMG)|interpro:IPR022097|interpro:IPR032643|interpro:IPR036910|mint:P48431|rcsb pdb:1O4X|rcsb pdb:2LE4|rcsb pdb:6T7B|rcsb pdb:6T90|rcsb pdb:6WX7|rcsb pdb:6WX8|rcsb pdb:6WX9|rcsb pdb:6YOV|reactome:R-HSA-2892245|reactome:R-HSA-2892247|reactome:R-HSA-3769402|reactome:R-HSA-452723|reactome:R-HSA-6785807|reactome:R-HSA-8986944 ensembl:ENSG00000163535(gene)|ensembl:ENST00000357799(transcript)|go:"GO:0000070"(mitotic sister chromatid segregation)|go:"GO:0000775"(chromosome, centromeric region)|go:"GO:0000776"(kinetochore)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0016604"(nuclear body)|go:"GO:0030892"(mitotic cohesin complex)|go:"GO:0045143"(homologous chromosome segregation)|go:"GO:0051177"(meiotic sister chromatid cohesion)|go:"GO:0051301"(cell division)|go:"GO:0051754"(meiotic sister chromatid cohesion, centromeric)|interpro:IPR026706|interpro:IPR038889|mint:Q562F6|reactome:R-HSA-141444|reactome:R-HSA-2467813|reactome:R-HSA-2500257|reactome:R-HSA-5663220|reactome:R-HSA-68877|reactome:R-HSA-9648025|refseq:XP_011509036.1|refseq:NP_001153518.1|refseq:NP_689737.4|refseq:XP_005246402.1|dip:DIP-36615N go:"GO:0005634"(nucleus) - - figure legend:ST3 F2C|comment:proteins that were enriched in the induced sample more than 6-fold|dataset:Brain Disease - Neurological Diseases & Disorders|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-daoy)|taxid:9606(Homo sapiens DAOY cerebellar medulloblastoma cell line) - 2020/12/29 2020/12/29 rogid:cn8gYfKDpQc8J2ygnqny32sIyyU9606 rogid:lj8jTnNLhIEEqgqjvOrIJIS57yc9606 rigid:Cnhili6Os5i+9KsmWx3iqclZGC0 false tandem tag:n-n - - - psi-mi:"MI:0658"(multidimensional protein identification technology) psi-mi:"MI:0658"(multidimensional protein identification technology) uniprotkb:P48431 uniprotkb:Q9P2D1 intact:EBI-6124081|uniprotkb:Q14537|ensembl:ENSP00000323588 intact:EBI-3951683|uniprotkb:D0VBA5|uniprotkb:E9PNZ2|uniprotkb:Q05DI5|uniprotkb:Q2TAN4|uniprotkb:Q66K35|uniprotkb:Q7Z6C0|uniprotkb:Q7Z7Q2|uniprotkb:Q9NXA0|uniprotkb:Q9NXA3|intact:EBI-28967545|ensembl:ENSP00000392028 psi-mi:sox2_human(display_long)|uniprotkb:SOX2(gene name)|psi-mi:SOX2(display_short) psi-mi:chd7_human(display_long)|uniprotkb:CHD7(gene name)|psi-mi:CHD7(display_short)|uniprotkb:KIAA1416(gene name synonym)|uniprotkb:ATP-dependent helicase CHD7(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Cox et al. (2012) pubmed:23667531|imex:IM-28599 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-26574478|imex:IM-28599-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_003097.1|dip:DIP-59913N|ensembl:ENSG00000181449(gene)|ensembl:ENST00000325404(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001649"(osteoblast differentiation)|go:"GO:0001654"(eye development)|go:"GO:0001714"(endodermal cell fate specification)|go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006325"(chromatin organization)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0009611"(response to wounding)|go:"GO:0009653"(anatomical structure morphogenesis)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0021781"(glial cell fate commitment)|go:"GO:0021983"(pituitary gland development)|go:"GO:0021984"(adenohypophysis development)|go:"GO:0022409"(positive regulation of cell-cell adhesion)|go:"GO:0030154"(cell differentiation)|go:"GO:0030900"(forebrain development)|go:"GO:0035019"(somatic stem cell population maintenance)|go:"GO:0035198"(miRNA binding)|go:"GO:0042246"(tissue regeneration)|go:"GO:0043281"(regulation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0043410"(positive regulation of MAPK cascade)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045165"(cell fate commitment)|go:"GO:0045597"(positive regulation of cell differentiation)|go:"GO:0045665"(negative regulation of neuron differentiation)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048839"(inner ear development)|go:"GO:0050680"(negative regulation of epithelial cell proliferation)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0070848"(response to growth factor)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:0097150"(neuronal stem cell population maintenance)|interpro:IPR009071(High mobility group box, HMG)|interpro:IPR022097|interpro:IPR032643|interpro:IPR036910|mint:P48431|rcsb pdb:1O4X|rcsb pdb:2LE4|rcsb pdb:6T7B|rcsb pdb:6T90|rcsb pdb:6WX7|rcsb pdb:6WX8|rcsb pdb:6WX9|rcsb pdb:6YOV|reactome:R-HSA-2892245|reactome:R-HSA-2892247|reactome:R-HSA-3769402|reactome:R-HSA-452723|reactome:R-HSA-6785807|reactome:R-HSA-8986944 ensembl:ENSP00000392028|ensembl:ENST00000524602|ensembl:ENSP00000437061|ensembl:ENST00000525508|ensembl:ENSP00000436027|refseq:NP_001303619.1|refseq:NP_060250.2|dip:DIP-48685N|ensembl:ENSG00000171316(gene)|ensembl:ENST00000423902(transcript)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0001501"(skeletal system development)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0001974"(blood vessel remodeling)|go:"GO:0003007"(heart morphogenesis)|go:"GO:0003222"(ventricular trabecula myocardium morphogenesis)|go:"GO:0003226"(right ventricular compact myocardium morphogenesis)|go:"GO:0003678"(DNA helicase activity)|go:"GO:0003682"(chromatin binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006364"(rRNA processing)|go:"GO:0007417"(central nervous system development)|go:"GO:0007512"(adult heart development)|go:"GO:0007605"(sensory perception of sound)|go:"GO:0007628"(adult walking behavior)|go:"GO:0008015"(blood circulation)|go:"GO:0009617"(response to bacterium)|go:"GO:0010880"(regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum)|go:"GO:0021545"(cranial nerve development)|go:"GO:0021553"(olfactory nerve development)|go:"GO:0021772"(olfactory bulb development)|go:"GO:0030217"(T cell differentiation)|go:"GO:0030540"(female genitalia development)|go:"GO:0035116"(embryonic hindlimb morphogenesis)|go:"GO:0035909"(aorta morphogenesis)|go:"GO:0036302"(atrioventricular canal development)|go:"GO:0040018"(positive regulation of multicellular organism growth)|go:"GO:0042048"(olfactory behavior)|go:"GO:0042472"(inner ear morphogenesis)|go:"GO:0043584"(nose development)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048752"(semicircular canal morphogenesis)|go:"GO:0048806"(genitalia development)|go:"GO:0050767"(regulation of neurogenesis)|go:"GO:0050890"(cognition)|go:"GO:0060041"(retina development in camera-type eye)|go:"GO:0060123"(regulation of growth hormone secretion)|go:"GO:0060324"(face development)|go:"GO:0060384"(innervation)|go:"GO:0060411"(cardiac septum morphogenesis)|go:"GO:0060429"(epithelium development)|go:"GO:0062009"(secondary palate development)|go:"GO:0070615"|go:"GO:0140603"(obsolete ATP hydrolysis activity)|go:"GO:1990841"(promoter-specific chromatin binding)|interpro:IPR000330(SNF2-related)|interpro:IPR000953(Chromo domain)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR006576(BRK)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR016197(Chromo domain-like)|interpro:IPR023780|interpro:IPR027417|interpro:IPR037259|go:"GO:0060173"(limb development)|interpro:IPR038718|mint:Q9P2D1|rcsb pdb:2CKC|rcsb pdb:2V0E|rcsb pdb:2V0F go:"GO:0005634"(nucleus) - - figure legend:ST3 F2C|comment:proteins that were enriched in the induced sample more than 6-fold|dataset:Brain Disease - Neurological Diseases & Disorders|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-daoy)|taxid:9606(Homo sapiens DAOY cerebellar medulloblastoma cell line) - 2020/12/29 2020/12/29 rogid:cn8gYfKDpQc8J2ygnqny32sIyyU9606 rogid:TwKt9rt8nB0sdxPgchCTyxEfq/k9606 rigid:Cnhili6Os5i+9KsmWx3iqclZGC0 false tandem tag:n-n - - - psi-mi:"MI:0658"(multidimensional protein identification technology) psi-mi:"MI:0658"(multidimensional protein identification technology) uniprotkb:P48431 uniprotkb:Q3L8U1 intact:EBI-6124081|uniprotkb:Q14537|ensembl:ENSP00000323588 intact:EBI-924707|uniprotkb:B9ZVQ0|uniprotkb:Q9UHM2|uniprotkb:O15025|uniprotkb:Q1WF12|uniprotkb:Q6DTK9|uniprotkb:Q9H9V7|uniprotkb:B2RTU2|ensembl:ENSP00000381522|ensembl:ENSP00000396345 psi-mi:sox2_human(display_long)|uniprotkb:SOX2(gene name)|psi-mi:SOX2(display_short) psi-mi:chd9_human(display_long)|uniprotkb:ATP-dependent helicase CHD9(gene name synonym)|uniprotkb:Chromatin-related mesenchymal modulator(gene name synonym)|uniprotkb:Chromatin-remodeling factor CHROM1(gene name synonym)|uniprotkb:Peroxisomal proliferator-activated receptor A-interacting complex 320 kDa protein(gene name synonym)|uniprotkb:PPAR-alpha-interacting complex protein 320 kDa(gene name synonym)|uniprotkb:Kismet homolog 2(gene name synonym)|uniprotkb:AD-013(orf name)|uniprotkb:x0008(orf name)|uniprotkb:CHD9(gene name)|psi-mi:CHD9(display_short)|uniprotkb:KIAA0308(gene name synonym)|uniprotkb:KISH2(gene name synonym)|uniprotkb:PRIC320(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Cox et al. (2012) pubmed:23667531|imex:IM-28599 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-26574478|imex:IM-28599-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_003097.1|dip:DIP-59913N|ensembl:ENSG00000181449(gene)|ensembl:ENST00000325404(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001649"(osteoblast differentiation)|go:"GO:0001654"(eye development)|go:"GO:0001714"(endodermal cell fate specification)|go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006325"(chromatin organization)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0009611"(response to wounding)|go:"GO:0009653"(anatomical structure morphogenesis)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0021781"(glial cell fate commitment)|go:"GO:0021983"(pituitary gland development)|go:"GO:0021984"(adenohypophysis development)|go:"GO:0022409"(positive regulation of cell-cell adhesion)|go:"GO:0030154"(cell differentiation)|go:"GO:0030900"(forebrain development)|go:"GO:0035019"(somatic stem cell population maintenance)|go:"GO:0035198"(miRNA binding)|go:"GO:0042246"(tissue regeneration)|go:"GO:0043281"(regulation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0043410"(positive regulation of MAPK cascade)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045165"(cell fate commitment)|go:"GO:0045597"(positive regulation of cell differentiation)|go:"GO:0045665"(negative regulation of neuron differentiation)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048839"(inner ear development)|go:"GO:0050680"(negative regulation of epithelial cell proliferation)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0070848"(response to growth factor)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:0097150"(neuronal stem cell population maintenance)|interpro:IPR009071(High mobility group box, HMG)|interpro:IPR022097|interpro:IPR032643|interpro:IPR036910|mint:P48431|rcsb pdb:1O4X|rcsb pdb:2LE4|rcsb pdb:6T7B|rcsb pdb:6T90|rcsb pdb:6WX7|rcsb pdb:6WX8|rcsb pdb:6WX9|rcsb pdb:6YOV|reactome:R-HSA-2892245|reactome:R-HSA-2892247|reactome:R-HSA-3769402|reactome:R-HSA-452723|reactome:R-HSA-6785807|reactome:R-HSA-8986944 refseq:NP_079410.4|refseq:XP_016879210.1|refseq:XP_016879211.1|refseq:XP_016879212.1|refseq:NP_001295248.1|refseq:XP_005256229.1|ensembl:ENSG00000177200(gene)|ensembl:ENST00000398510(transcript)|ensembl:ENST00000447540(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0003678"(DNA helicase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006325"(chromatin organization)|go:"GO:0070615"|go:"GO:0140603"(obsolete ATP hydrolysis activity)|interpro:IPR000330(SNF2-related)|interpro:IPR000953(Chromo domain)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR006576(BRK)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR016197(Chromo domain-like)|interpro:IPR023780|interpro:IPR027417|interpro:IPR037259|interpro:IPR038718|interpro:IPR042850|mint:Q3L8U1|reactome:R-HSA-1368082|reactome:R-HSA-1368108|reactome:R-HSA-1989781|reactome:R-HSA-2151201|reactome:R-HSA-2426168|reactome:R-HSA-381340|reactome:R-HSA-400206|reactome:R-HSA-400253|reactome:R-HSA-9707564|reactome:R-HSA-9707616 go:"GO:0005634"(nucleus) - - figure legend:ST3 F2C|comment:proteins that were enriched in the induced sample more than 6-fold|dataset:Brain Disease - Neurological Diseases & Disorders|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-daoy)|taxid:9606(Homo sapiens DAOY cerebellar medulloblastoma cell line) - 2020/12/29 2020/12/29 rogid:cn8gYfKDpQc8J2ygnqny32sIyyU9606 rogid:jfarZZP0D/KbcnSYbocCzkWHgsw9606 rigid:Cnhili6Os5i+9KsmWx3iqclZGC0 false tandem tag:n-n - - - psi-mi:"MI:0658"(multidimensional protein identification technology) psi-mi:"MI:0658"(multidimensional protein identification technology) uniprotkb:P48431 uniprotkb:Q9P2K5 intact:EBI-6124081|uniprotkb:Q14537|ensembl:ENSP00000323588 intact:EBI-9675857|uniprotkb:A7MCZ9|uniprotkb:C9K0J4|uniprotkb:Q9NUQ1|uniprotkb:Q7Z4B7|uniprotkb:C9J921|uniprotkb:Q6NUM5|uniprotkb:Q9H922|uniprotkb:Q7L388 psi-mi:sox2_human(display_long)|uniprotkb:SOX2(gene name)|psi-mi:SOX2(display_short) psi-mi:myef2_human(display_long)|uniprotkb:MYEF2(gene name)|psi-mi:MYEF2(display_short)|uniprotkb:KIAA1341(gene name synonym)|uniprotkb:MST156(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Cox et al. (2012) pubmed:23667531|imex:IM-28599 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-26574478|imex:IM-28599-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_003097.1|dip:DIP-59913N|ensembl:ENSG00000181449(gene)|ensembl:ENST00000325404(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001649"(osteoblast differentiation)|go:"GO:0001654"(eye development)|go:"GO:0001714"(endodermal cell fate specification)|go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006325"(chromatin organization)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0009611"(response to wounding)|go:"GO:0009653"(anatomical structure morphogenesis)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0021781"(glial cell fate commitment)|go:"GO:0021983"(pituitary gland development)|go:"GO:0021984"(adenohypophysis development)|go:"GO:0022409"(positive regulation of cell-cell adhesion)|go:"GO:0030154"(cell differentiation)|go:"GO:0030900"(forebrain development)|go:"GO:0035019"(somatic stem cell population maintenance)|go:"GO:0035198"(miRNA binding)|go:"GO:0042246"(tissue regeneration)|go:"GO:0043281"(regulation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0043410"(positive regulation of MAPK cascade)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045165"(cell fate commitment)|go:"GO:0045597"(positive regulation of cell differentiation)|go:"GO:0045665"(negative regulation of neuron differentiation)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048839"(inner ear development)|go:"GO:0050680"(negative regulation of epithelial cell proliferation)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0070848"(response to growth factor)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:0097150"(neuronal stem cell population maintenance)|interpro:IPR009071(High mobility group box, HMG)|interpro:IPR022097|interpro:IPR032643|interpro:IPR036910|mint:P48431|rcsb pdb:1O4X|rcsb pdb:2LE4|rcsb pdb:6T7B|rcsb pdb:6T90|rcsb pdb:6WX7|rcsb pdb:6WX8|rcsb pdb:6WX9|rcsb pdb:6YOV|reactome:R-HSA-2892245|reactome:R-HSA-2892247|reactome:R-HSA-3769402|reactome:R-HSA-452723|reactome:R-HSA-6785807|reactome:R-HSA-8986944 interpro:IPR000504(RNA recognition motif, RNP-1)|refseq:NP_057216.2|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|mint:Q9P2K5|refseq:NP_001288139.1|interpro:IPR034630|interpro:IPR034631|interpro:IPR034632|interpro:IPR035979|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0014902"(myotube differentiation)|go:"GO:0030182"(neuron differentiation)|go:"GO:0071014"(post-mRNA release spliceosomal complex)|go:"GO:1990904"(ribonucleoprotein complex)|go:"GO:2000815"(regulation of mRNA stability involved in response to oxidative stress) go:"GO:0005634"(nucleus) - - figure legend:ST3 F2C|comment:proteins that were enriched in the induced sample more than 6-fold|dataset:Brain Disease - Neurological Diseases & Disorders|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-daoy)|taxid:9606(Homo sapiens DAOY cerebellar medulloblastoma cell line) - 2020/12/29 2020/12/29 rogid:cn8gYfKDpQc8J2ygnqny32sIyyU9606 rogid:v/dNVOlL/ndJDraGpMrPedvq/FU9606 rigid:Cnhili6Os5i+9KsmWx3iqclZGC0 false tandem tag:n-n - - - psi-mi:"MI:0658"(multidimensional protein identification technology) psi-mi:"MI:0658"(multidimensional protein identification technology) uniprotkb:P48431 uniprotkb:Q9Y333 intact:EBI-6124081|uniprotkb:Q14537|ensembl:ENSP00000323588 intact:EBI-347416|uniprotkb:Q6FGG1|ensembl:ENSP00000414006|ensembl:ENSP00000414634|ensembl:ENSP00000406280|ensembl:ENSP00000364813|ensembl:ENSP00000372883|ensembl:ENSP00000403345 psi-mi:sox2_human(display_long)|uniprotkb:SOX2(gene name)|psi-mi:SOX2(display_short) psi-mi:lsm2_human(display_long)|uniprotkb:LSM2(gene name)|psi-mi:LSM2(display_short)|uniprotkb:C6orf28(gene name synonym)|uniprotkb:G7B(gene name synonym)|uniprotkb:snRNP core Sm-like protein Sm-x5(gene name synonym)|uniprotkb:Small nuclear ribonuclear protein D homolog(gene name synonym)|uniprotkb:Protein G7b(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Cox et al. (2012) pubmed:23667531|imex:IM-28599 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-26574478|imex:IM-28599-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_003097.1|dip:DIP-59913N|ensembl:ENSG00000181449(gene)|ensembl:ENST00000325404(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001649"(osteoblast differentiation)|go:"GO:0001654"(eye development)|go:"GO:0001714"(endodermal cell fate specification)|go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006325"(chromatin organization)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0009611"(response to wounding)|go:"GO:0009653"(anatomical structure morphogenesis)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0021781"(glial cell fate commitment)|go:"GO:0021983"(pituitary gland development)|go:"GO:0021984"(adenohypophysis development)|go:"GO:0022409"(positive regulation of cell-cell adhesion)|go:"GO:0030154"(cell differentiation)|go:"GO:0030900"(forebrain development)|go:"GO:0035019"(somatic stem cell population maintenance)|go:"GO:0035198"(miRNA binding)|go:"GO:0042246"(tissue regeneration)|go:"GO:0043281"(regulation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0043410"(positive regulation of MAPK cascade)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045165"(cell fate commitment)|go:"GO:0045597"(positive regulation of cell differentiation)|go:"GO:0045665"(negative regulation of neuron differentiation)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048839"(inner ear development)|go:"GO:0050680"(negative regulation of epithelial cell proliferation)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0070848"(response to growth factor)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:0097150"(neuronal stem cell population maintenance)|interpro:IPR009071(High mobility group box, HMG)|interpro:IPR022097|interpro:IPR032643|interpro:IPR036910|mint:P48431|rcsb pdb:1O4X|rcsb pdb:2LE4|rcsb pdb:6T7B|rcsb pdb:6T90|rcsb pdb:6WX7|rcsb pdb:6WX8|rcsb pdb:6WX9|rcsb pdb:6YOV|reactome:R-HSA-2892245|reactome:R-HSA-2892247|reactome:R-HSA-3769402|reactome:R-HSA-452723|reactome:R-HSA-6785807|reactome:R-HSA-8986944 refseq:NP_067000.1|ensembl:ENST00000375661(transcript)|ensembl:ENST00000383391(transcript)|ensembl:ENST00000424975(transcript)|ensembl:ENST00000432122(transcript)|ensembl:ENST00000434125(transcript)|ensembl:ENST00000455705(transcript)|go:"GO:0000244"(spliceosomal tri-snRNP complex assembly)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0000932"(P-body)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005688"(U6 snRNP)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006402"(mRNA catabolic process)|go:"GO:0017070"(U6 snRNA binding)|go:"GO:0031267"(small GTPase binding)|go:"GO:0046540"(U4/U6 x U5 tri-snRNP complex)|go:"GO:0071005"(U2-type precatalytic spliceosome)|go:"GO:0071011"(precatalytic spliceosome)|go:"GO:0071013"(catalytic step 2 spliceosome)|go:"GO:0120115"(Lsm2-8 complex)|go:"GO:1990726"(Lsm1-7-Pat1 complex)|interpro:IPR001163(Like-Sm ribonucleoprotein, core)|interpro:IPR010920(Like-Sm ribonucleoprotein-related, core)|interpro:IPR016654(U6 snRNA-associated Sm-like protein LSm2)|mint:Q9Y333|rcsb pdb:3JCR|rcsb pdb:5O9Z|rcsb pdb:6AH0|rcsb pdb:6AHD|rcsb pdb:6QW6|rcsb pdb:6QX9|rcsb pdb:7ABG|reactome:R-HSA-430039|reactome:R-HSA-72163|reactome:R-HSA-72165|ensembl:ENSG00000172850(gene)|ensembl:ENSG00000204392(gene)|ensembl:ENSG00000224979(gene)|ensembl:ENSG00000225998(gene)|ensembl:ENSG00000231502(gene)|ensembl:ENSG00000236826(gene)|dip:DIP-31139N go:"GO:0005634"(nucleus) - - figure legend:ST3 F2C|comment:proteins that were enriched in the induced sample more than 6-fold|dataset:Brain Disease - Neurological Diseases & Disorders|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-daoy)|taxid:9606(Homo sapiens DAOY cerebellar medulloblastoma cell line) - 2020/12/29 2020/12/29 rogid:cn8gYfKDpQc8J2ygnqny32sIyyU9606 rogid:lReyYTJxC/WlYg/ekKaqZiNNdVM9606 rigid:Cnhili6Os5i+9KsmWx3iqclZGC0 false tandem tag:n-n - - - psi-mi:"MI:0658"(multidimensional protein identification technology) psi-mi:"MI:0658"(multidimensional protein identification technology) uniprotkb:P48431 uniprotkb:P25705 intact:EBI-6124081|uniprotkb:Q14537|ensembl:ENSP00000323588 intact:EBI-351437|uniprotkb:Q53XX6|uniprotkb:Q8IXV2|uniprotkb:Q96FB4|uniprotkb:Q96HW2|uniprotkb:Q96IR6|uniprotkb:Q9BTV8|intact:EBI-11032691|uniprotkb:A8K092|uniprotkb:B4DY56|uniprotkb:K7ENP3|ensembl:ENSP00000282050|ensembl:ENSP00000381736 psi-mi:sox2_human(display_long)|uniprotkb:SOX2(gene name)|psi-mi:SOX2(display_short) psi-mi:atpa_human(display_long)|uniprotkb:ATP5F1A(gene name)|psi-mi:ATP5F1A(display_short)|uniprotkb:ATP synthase F1 subunit alpha(gene name synonym)|uniprotkb:ATP5A(gene name synonym)|uniprotkb:ATP5A1(gene name synonym)|uniprotkb:ATP5AL2(gene name synonym)|uniprotkb:ATPM(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Cox et al. (2012) pubmed:23667531|imex:IM-28599 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-26574478|imex:IM-28599-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_003097.1|dip:DIP-59913N|ensembl:ENSG00000181449(gene)|ensembl:ENST00000325404(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001649"(osteoblast differentiation)|go:"GO:0001654"(eye development)|go:"GO:0001714"(endodermal cell fate specification)|go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006325"(chromatin organization)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0009611"(response to wounding)|go:"GO:0009653"(anatomical structure morphogenesis)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0021781"(glial cell fate commitment)|go:"GO:0021983"(pituitary gland development)|go:"GO:0021984"(adenohypophysis development)|go:"GO:0022409"(positive regulation of cell-cell adhesion)|go:"GO:0030154"(cell differentiation)|go:"GO:0030900"(forebrain development)|go:"GO:0035019"(somatic stem cell population maintenance)|go:"GO:0035198"(miRNA binding)|go:"GO:0042246"(tissue regeneration)|go:"GO:0043281"(regulation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0043410"(positive regulation of MAPK cascade)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045165"(cell fate commitment)|go:"GO:0045597"(positive regulation of cell differentiation)|go:"GO:0045665"(negative regulation of neuron differentiation)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048839"(inner ear development)|go:"GO:0050680"(negative regulation of epithelial cell proliferation)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0070848"(response to growth factor)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:0097150"(neuronal stem cell population maintenance)|interpro:IPR009071(High mobility group box, HMG)|interpro:IPR022097|interpro:IPR032643|interpro:IPR036910|mint:P48431|rcsb pdb:1O4X|rcsb pdb:2LE4|rcsb pdb:6T7B|rcsb pdb:6T90|rcsb pdb:6WX7|rcsb pdb:6WX8|rcsb pdb:6WX9|rcsb pdb:6YOV|reactome:R-HSA-2892245|reactome:R-HSA-2892247|reactome:R-HSA-3769402|reactome:R-HSA-452723|reactome:R-HSA-6785807|reactome:R-HSA-8986944 refseq:NP_001244263.1|refseq:NP_001001937.1|refseq:NP_004037.1|refseq:NP_001001935.1|refseq:NP_001244264.1|dip:DIP-32871N|ensembl:ENSG00000152234(gene)|ensembl:ENST00000282050(transcript)|ensembl:ENST00000398752(transcript)|go:"GO:0001937"(negative regulation of endothelial cell proliferation)|go:"GO:0003723"(RNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005753"(mitochondrial proton-transporting ATP synthase complex)|go:"GO:0005754"(mitochondrial proton-transporting ATP synthase, catalytic core)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0005886"(plasma membrane)|go:"GO:0006629"(lipid metabolic process)|go:"GO:0006754"(ATP biosynthetic process)|go:"GO:0015986"(ATP synthesis coupled proton transport)|go:"GO:0016020"(membrane)|go:"GO:0042288"(MHC class I protein binding)|go:"GO:0042776"(mitochondrial ATP synthesis coupled proton transport)|go:"GO:0043531"(ADP binding)|go:"GO:0043532"(angiostatin binding)|go:"GO:0043536"(positive regulation of blood vessel endothelial cell migration)|go:"GO:0045259"(proton-transporting ATP synthase complex)|go:"GO:0045261"("proton-transporting ATP synthase complex, catalytic core F(1)")|go:"GO:0046933"(proton-transporting ATP synthase activity, rotational mechanism)|go:"GO:0070062"(extracellular exosome)|interpro:IPR000194(ATPase, F1/V1/A1 complex, alpha/beta subunit, nucleotide-binding)|interpro:IPR000793(ATPase, F1/V1/A1 complex, alpha/beta subunit, C-terminal)|interpro:IPR004100(ATPase, F1/V1/A1 complex, alpha/beta subunit, N-terminal)|interpro:IPR005294(ATPase, F1 complex, alpha subunit)|interpro:IPR020003|interpro:IPR023366|interpro:IPR027417|interpro:IPR033732|interpro:IPR036121|interpro:IPR038376|mint:P25705|reactome:R-HSA-1268020|reactome:R-HSA-163210|reactome:R-HSA-8949613 go:"GO:0005634"(nucleus) - - figure legend:ST3 F2C|comment:proteins that were enriched in the induced sample more than 6-fold|dataset:Brain Disease - Neurological Diseases & Disorders|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-daoy)|taxid:9606(Homo sapiens DAOY cerebellar medulloblastoma cell line) - 2020/12/29 2020/12/29 rogid:cn8gYfKDpQc8J2ygnqny32sIyyU9606 rogid:Sy/Ii5ea+ilCKGBnIEMn133Vogc9606 rigid:Cnhili6Os5i+9KsmWx3iqclZGC0 false tandem tag:n-n - - - psi-mi:"MI:0658"(multidimensional protein identification technology) psi-mi:"MI:0658"(multidimensional protein identification technology) uniprotkb:P48431 uniprotkb:Q12824 intact:EBI-6124081|uniprotkb:Q14537|ensembl:ENSP00000323588 intact:EBI-358419|uniprotkb:O75784|uniprotkb:O95474|uniprotkb:Q38GA1|uniprotkb:Q76N08|uniprotkb:Q9UBH2|ensembl:ENSP00000479330|ensembl:ENSP00000494049|uniprotkb:Q17S11 psi-mi:sox2_human(display_long)|uniprotkb:SOX2(gene name)|psi-mi:SOX2(display_short) psi-mi:snf5_human(display_long)|uniprotkb:SMARCB1(gene name)|psi-mi:SMARCB1(display_short)|uniprotkb:INI1(gene name synonym)|uniprotkb:SNF5L1(gene name synonym)|uniprotkb:Integrase interactor 1 protein(gene name synonym)|uniprotkb:BAF47(gene name synonym)|uniprotkb:SNF5 homolog(gene name synonym)|uniprotkb:BRG1-associated factor 47(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Cox et al. (2012) pubmed:23667531|imex:IM-28599 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-26574478|imex:IM-28599-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_003097.1|dip:DIP-59913N|ensembl:ENSG00000181449(gene)|ensembl:ENST00000325404(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001649"(osteoblast differentiation)|go:"GO:0001654"(eye development)|go:"GO:0001714"(endodermal cell fate specification)|go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006325"(chromatin organization)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0009611"(response to wounding)|go:"GO:0009653"(anatomical structure morphogenesis)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0021781"(glial cell fate commitment)|go:"GO:0021983"(pituitary gland development)|go:"GO:0021984"(adenohypophysis development)|go:"GO:0022409"(positive regulation of cell-cell adhesion)|go:"GO:0030154"(cell differentiation)|go:"GO:0030900"(forebrain development)|go:"GO:0035019"(somatic stem cell population maintenance)|go:"GO:0035198"(miRNA binding)|go:"GO:0042246"(tissue regeneration)|go:"GO:0043281"(regulation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0043410"(positive regulation of MAPK cascade)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045165"(cell fate commitment)|go:"GO:0045597"(positive regulation of cell differentiation)|go:"GO:0045665"(negative regulation of neuron differentiation)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048839"(inner ear development)|go:"GO:0050680"(negative regulation of epithelial cell proliferation)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0070848"(response to growth factor)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:0097150"(neuronal stem cell population maintenance)|interpro:IPR009071(High mobility group box, HMG)|interpro:IPR022097|interpro:IPR032643|interpro:IPR036910|mint:P48431|rcsb pdb:1O4X|rcsb pdb:2LE4|rcsb pdb:6T7B|rcsb pdb:6T90|rcsb pdb:6WX7|rcsb pdb:6WX8|rcsb pdb:6WX9|rcsb pdb:6YOV|reactome:R-HSA-2892245|reactome:R-HSA-2892247|reactome:R-HSA-3769402|reactome:R-HSA-452723|reactome:R-HSA-6785807|reactome:R-HSA-8986944 mint:Q12824|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|rcsb pdb:5AJ1|rcsb pdb:5GJK|rcsb pdb:5L7A|rcsb pdb:5L7B|go:"GO:0007049"(cell cycle)|rcsb pdb:6AX5|go:"GO:0007399"(nervous system development)|rcsb pdb:6KAG|rcsb pdb:6KZ7|rcsb pdb:6LTH|rcsb pdb:6LTJ|rcsb pdb:6UCH|reactome:R-HSA-3214858|go:"GO:0008285"(negative regulation of cell population proliferation)|reactome:R-HSA-8939243|go:"GO:0015074"(DNA integration)|go:"GO:0016514"(SWI/SNF complex)|go:"GO:0030154"(cell differentiation)|go:"GO:0030957"(Tat protein binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035060"(brahma complex)|go:"GO:0039692"(single stranded viral RNA replication via double stranded DNA intermediate)|go:"GO:0043044"|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0043923"(positive regulation by host of viral transcription)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0071564"(npBAF complex)|go:"GO:0071565"(nBAF complex)|go:"GO:0090240"(positive regulation of histone H4 acetylation)|go:"GO:1900110"(negative regulation of histone H3-K9 dimethylation)|go:"GO:1900113"(negative regulation of histone H3-K9 trimethylation)|go:"GO:1901838"(positive regulation of transcription of nucleolar large rRNA by RNA polymerase I)|go:"GO:1902661"(positive regulation of glucose mediated signaling pathway)|go:"GO:2000617"(positive regulation of histone H3-K9 acetylation)|interpro:IPR006939(SNF5/SMARCB1/INI1)|interpro:IPR017393(SWI/SNF chromatin-remodeling complex, component hSNF5/Ini1)|go:"GO:0005730"(nucleolus)|go:"GO:0006337"(nucleosome disassembly)|go:"GO:0006338"(chromatin remodeling)|refseq:NP_001007469.1|refseq:NP_003064.2|ensembl:ENSG00000099956(gene)|ensembl:ENSG00000275837(gene)|ensembl:ENST00000618915(transcript)|ensembl:ENST00000644036(transcript)|go:"GO:0000228"(nuclear chromosome)|go:"GO:0000785"(chromatin)|go:"GO:0001188"(RNA polymerase I preinitiation complex assembly)|go:"GO:0001650"(fibrillar center)|go:"GO:0001741"(XY body)|go:"GO:0001835"(blastocyst hatching)|go:"GO:0002039"(p53 binding)|go:"GO:0003677"(DNA binding)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|dip:DIP-27550N go:"GO:0005634"(nucleus) - - figure legend:ST3 F2C|comment:proteins that were enriched in the induced sample more than 6-fold|dataset:Brain Disease - Neurological Diseases & Disorders|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-daoy)|taxid:9606(Homo sapiens DAOY cerebellar medulloblastoma cell line) - 2020/12/29 2020/12/29 rogid:cn8gYfKDpQc8J2ygnqny32sIyyU9606 rogid:GjUm1RYfDvtNuSNGI6iCWpl8L+I9606 rigid:Cnhili6Os5i+9KsmWx3iqclZGC0 false tandem tag:n-n - - - psi-mi:"MI:0658"(multidimensional protein identification technology) psi-mi:"MI:0658"(multidimensional protein identification technology) uniprotkb:P48431 uniprotkb:Q9Y5L0 intact:EBI-6124081|uniprotkb:Q14537|ensembl:ENSP00000323588 intact:EBI-1042571|uniprotkb:A4D1K9|uniprotkb:Q6NUM1|uniprotkb:Q96G71|uniprotkb:Q96GU9|uniprotkb:Q9Y3R2|uniprotkb:C9IZM0|ensembl:ENSP00000265388 psi-mi:sox2_human(display_long)|uniprotkb:SOX2(gene name)|psi-mi:SOX2(display_short) psi-mi:tnpo3_human(display_long)|uniprotkb:TNPO3(gene name)|psi-mi:TNPO3(display_short)|uniprotkb:IPO12(gene name synonym)|uniprotkb:Transportin-SR(gene name synonym)|uniprotkb:Importin-12(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Cox et al. (2012) pubmed:23667531|imex:IM-28599 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-26574478|imex:IM-28599-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_003097.1|dip:DIP-59913N|ensembl:ENSG00000181449(gene)|ensembl:ENST00000325404(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001649"(osteoblast differentiation)|go:"GO:0001654"(eye development)|go:"GO:0001714"(endodermal cell fate specification)|go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006325"(chromatin organization)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0009611"(response to wounding)|go:"GO:0009653"(anatomical structure morphogenesis)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0021781"(glial cell fate commitment)|go:"GO:0021983"(pituitary gland development)|go:"GO:0021984"(adenohypophysis development)|go:"GO:0022409"(positive regulation of cell-cell adhesion)|go:"GO:0030154"(cell differentiation)|go:"GO:0030900"(forebrain development)|go:"GO:0035019"(somatic stem cell population maintenance)|go:"GO:0035198"(miRNA binding)|go:"GO:0042246"(tissue regeneration)|go:"GO:0043281"(regulation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0043410"(positive regulation of MAPK cascade)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045165"(cell fate commitment)|go:"GO:0045597"(positive regulation of cell differentiation)|go:"GO:0045665"(negative regulation of neuron differentiation)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048839"(inner ear development)|go:"GO:0050680"(negative regulation of epithelial cell proliferation)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0070848"(response to growth factor)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:0097150"(neuronal stem cell population maintenance)|interpro:IPR009071(High mobility group box, HMG)|interpro:IPR022097|interpro:IPR032643|interpro:IPR036910|mint:P48431|rcsb pdb:1O4X|rcsb pdb:2LE4|rcsb pdb:6T7B|rcsb pdb:6T90|rcsb pdb:6WX7|rcsb pdb:6WX8|rcsb pdb:6WX9|rcsb pdb:6YOV|reactome:R-HSA-2892245|reactome:R-HSA-2892247|reactome:R-HSA-3769402|reactome:R-HSA-452723|reactome:R-HSA-6785807|reactome:R-HSA-8986944 refseq:NP_001177957.2|refseq:NP_036602.1|ensembl:ENSG00000064419(gene)|ensembl:ENST00000265388(transcript)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005642"(annulate lamellae)|go:"GO:0005737"(cytoplasm)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0031267"(small GTPase binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0061608"(nuclear import signal receptor activity)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR013598(Exportin-1/Importin-beta-like)|interpro:IPR016024(Armadillo-type fold)|mint:Q9Y5L0|rcsb pdb:4C0O|rcsb pdb:4C0P|rcsb pdb:4C0Q|rcsb pdb:4OL0|rcsb pdb:6GX9 go:"GO:0005634"(nucleus) - - figure legend:ST3 F2C|comment:proteins that were enriched in the induced sample more than 6-fold|dataset:Brain Disease - Neurological Diseases & Disorders|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-daoy)|taxid:9606(Homo sapiens DAOY cerebellar medulloblastoma cell line) - 2020/12/29 2020/12/29 rogid:cn8gYfKDpQc8J2ygnqny32sIyyU9606 rogid:Xvd5fZ4wlMc6R6w2wL+JhIOOuIE9606 rigid:Cnhili6Os5i+9KsmWx3iqclZGC0 false tandem tag:n-n - - - psi-mi:"MI:0658"(multidimensional protein identification technology) psi-mi:"MI:0658"(multidimensional protein identification technology) uniprotkb:P48431 uniprotkb:Q9NXF1 intact:EBI-6124081|uniprotkb:Q14537|ensembl:ENSP00000323588 intact:EBI-2371062|uniprotkb:Q5T722|uniprotkb:Q5T723|uniprotkb:Q8NCN8|uniprotkb:Q8TDY0|uniprotkb:B4DYV2|ensembl:ENSP00000364037 psi-mi:sox2_human(display_long)|uniprotkb:SOX2(gene name)|psi-mi:SOX2(display_short) psi-mi:tex10_human(display_long)|uniprotkb:TEX10(gene name)|psi-mi:TEX10(display_short)|uniprotkb:L18(orf name)|uniprotkb:Nbla10363(orf name) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Cox et al. (2012) pubmed:23667531|imex:IM-28599 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-26574478|imex:IM-28599-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_003097.1|dip:DIP-59913N|ensembl:ENSG00000181449(gene)|ensembl:ENST00000325404(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001649"(osteoblast differentiation)|go:"GO:0001654"(eye development)|go:"GO:0001714"(endodermal cell fate specification)|go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006325"(chromatin organization)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0009611"(response to wounding)|go:"GO:0009653"(anatomical structure morphogenesis)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0021781"(glial cell fate commitment)|go:"GO:0021983"(pituitary gland development)|go:"GO:0021984"(adenohypophysis development)|go:"GO:0022409"(positive regulation of cell-cell adhesion)|go:"GO:0030154"(cell differentiation)|go:"GO:0030900"(forebrain development)|go:"GO:0035019"(somatic stem cell population maintenance)|go:"GO:0035198"(miRNA binding)|go:"GO:0042246"(tissue regeneration)|go:"GO:0043281"(regulation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0043410"(positive regulation of MAPK cascade)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045165"(cell fate commitment)|go:"GO:0045597"(positive regulation of cell differentiation)|go:"GO:0045665"(negative regulation of neuron differentiation)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048839"(inner ear development)|go:"GO:0050680"(negative regulation of epithelial cell proliferation)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0070848"(response to growth factor)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:0097150"(neuronal stem cell population maintenance)|interpro:IPR009071(High mobility group box, HMG)|interpro:IPR022097|interpro:IPR032643|interpro:IPR036910|mint:P48431|rcsb pdb:1O4X|rcsb pdb:2LE4|rcsb pdb:6T7B|rcsb pdb:6T90|rcsb pdb:6WX7|rcsb pdb:6WX8|rcsb pdb:6WX9|rcsb pdb:6YOV|reactome:R-HSA-2892245|reactome:R-HSA-2892247|reactome:R-HSA-3769402|reactome:R-HSA-452723|reactome:R-HSA-6785807|reactome:R-HSA-8986944 refseq:NP_060216.2|refseq:NP_001155056.1|ensembl:ENSG00000136891(gene)|ensembl:ENST00000374902(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005739"(mitochondrion)|go:"GO:0071339"(MLL1 complex)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR021133|interpro:IPR024679|interpro:IPR037947|mint:Q9NXF1|reactome:R-HSA-6791226 go:"GO:0005634"(nucleus) - - figure legend:ST3 F2C|comment:proteins that were enriched in the induced sample more than 6-fold|dataset:Brain Disease - Neurological Diseases & Disorders|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-daoy)|taxid:9606(Homo sapiens DAOY cerebellar medulloblastoma cell line) - 2020/12/29 2020/12/29 rogid:cn8gYfKDpQc8J2ygnqny32sIyyU9606 rogid:cQcRo1eExRkr/an7wvBN8Ttyatc9606 rigid:Cnhili6Os5i+9KsmWx3iqclZGC0 false tandem tag:n-n - - - psi-mi:"MI:0658"(multidimensional protein identification technology) psi-mi:"MI:0658"(multidimensional protein identification technology) uniprotkb:P48431 uniprotkb:Q8N3C0 intact:EBI-6124081|uniprotkb:Q14537|ensembl:ENSP00000323588 intact:EBI-1210710|uniprotkb:Q9NTR0|uniprotkb:O43738|uniprotkb:Q5VTN2|uniprotkb:Q9H1I9|uniprotkb:E7EW23|uniprotkb:Q4G1A0|uniprotkb:Q9H5A2|ensembl:ENSP00000358159 psi-mi:sox2_human(display_long)|uniprotkb:SOX2(gene name)|psi-mi:SOX2(display_short) psi-mi:ascc3_human(display_long)|uniprotkb:ASCC3(gene name)|psi-mi:ASCC3(display_short)|uniprotkb:HELIC1(gene name synonym)|uniprotkb:ASC-1 complex subunit p200(gene name synonym)|uniprotkb:Trip4 complex subunit p200(gene name synonym)|uniprotkb:Helicase, ATP binding 1(gene name synonym)|uniprotkb:RQT2(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Cox et al. (2012) pubmed:23667531|imex:IM-28599 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-26574478|imex:IM-28599-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_003097.1|dip:DIP-59913N|ensembl:ENSG00000181449(gene)|ensembl:ENST00000325404(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001649"(osteoblast differentiation)|go:"GO:0001654"(eye development)|go:"GO:0001714"(endodermal cell fate specification)|go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006325"(chromatin organization)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0009611"(response to wounding)|go:"GO:0009653"(anatomical structure morphogenesis)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0021781"(glial cell fate commitment)|go:"GO:0021983"(pituitary gland development)|go:"GO:0021984"(adenohypophysis development)|go:"GO:0022409"(positive regulation of cell-cell adhesion)|go:"GO:0030154"(cell differentiation)|go:"GO:0030900"(forebrain development)|go:"GO:0035019"(somatic stem cell population maintenance)|go:"GO:0035198"(miRNA binding)|go:"GO:0042246"(tissue regeneration)|go:"GO:0043281"(regulation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0043410"(positive regulation of MAPK cascade)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045165"(cell fate commitment)|go:"GO:0045597"(positive regulation of cell differentiation)|go:"GO:0045665"(negative regulation of neuron differentiation)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048839"(inner ear development)|go:"GO:0050680"(negative regulation of epithelial cell proliferation)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0070848"(response to growth factor)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:0097150"(neuronal stem cell population maintenance)|interpro:IPR009071(High mobility group box, HMG)|interpro:IPR022097|interpro:IPR032643|interpro:IPR036910|mint:P48431|rcsb pdb:1O4X|rcsb pdb:2LE4|rcsb pdb:6T7B|rcsb pdb:6T90|rcsb pdb:6WX7|rcsb pdb:6WX8|rcsb pdb:6WX9|rcsb pdb:6YOV|reactome:R-HSA-2892245|reactome:R-HSA-2892247|reactome:R-HSA-3769402|reactome:R-HSA-452723|reactome:R-HSA-6785807|reactome:R-HSA-8986944 refseq:NP_001271200.1|refseq:NP_006819.2|refseq:NP_071374.1|ensembl:ENSG00000112249(gene)|ensembl:ENST00000369162(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006307"(DNA dealkylation involved in DNA repair)|go:"GO:0008283"(cell population proliferation)|go:"GO:0016020"(membrane)|go:"GO:0016607"(nuclear speck)|go:"GO:0032508"(DNA duplex unwinding)|go:"GO:0043138"(3'-5' DNA helicase activity)|go:"GO:0099053"(activating signal cointegrator 1 complex)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR004179(Sec63)|interpro:IPR011545(DNA/RNA helicase, DEAD/DEAH box type, N-terminal)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR014756(Immunoglobulin E-set)|interpro:IPR027417|interpro:IPR035892|interpro:IPR036388|interpro:IPR036390|mint:Q8N3C0|rcsb pdb:6YXQ|reactome:R-HSA-112126|go:"GO:0005829"(cytosol) go:"GO:0005634"(nucleus) - - figure legend:ST3 F2C|comment:proteins that were enriched in the induced sample more than 6-fold|dataset:Brain Disease - Neurological Diseases & Disorders|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-daoy)|taxid:9606(Homo sapiens DAOY cerebellar medulloblastoma cell line) - 2020/12/29 2020/12/29 rogid:cn8gYfKDpQc8J2ygnqny32sIyyU9606 rogid:HAdhxBtWHxdw7k0GkyqBtloVyPY9606 rigid:Cnhili6Os5i+9KsmWx3iqclZGC0 false tandem tag:n-n - - - psi-mi:"MI:0658"(multidimensional protein identification technology) psi-mi:"MI:0658"(multidimensional protein identification technology) uniprotkb:P48431 uniprotkb:Q96T37 intact:EBI-6124081|uniprotkb:Q14537|ensembl:ENSP00000323588 intact:EBI-2514922|ensembl:ENSP00000358799|ensembl:ENSP00000483133|uniprotkb:Q96SC9|uniprotkb:Q5D058|uniprotkb:Q96SD0|uniprotkb:Q5T613|uniprotkb:Q96SC5|uniprotkb:Q96T38|uniprotkb:Q9BRA5|uniprotkb:Q96SC6|uniprotkb:Q9H9Y0|uniprotkb:Q96PE4|uniprotkb:Q9H6R8|uniprotkb:Q4V760|uniprotkb:A1A693|uniprotkb:Q3ZB86|uniprotkb:Q86VW9 psi-mi:sox2_human(display_long)|uniprotkb:SOX2(gene name)|psi-mi:SOX2(display_short) psi-mi:rbm15_human(display_long)|uniprotkb:RBM15(gene name)|psi-mi:RBM15(display_short)|uniprotkb:OTT(gene name synonym)|uniprotkb:OTT1(gene name synonym)|uniprotkb:RNA-binding motif protein 15(gene name synonym)|uniprotkb:One-twenty two protein 1(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Cox et al. (2012) pubmed:23667531|imex:IM-28599 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-26574478|imex:IM-28599-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_003097.1|dip:DIP-59913N|ensembl:ENSG00000181449(gene)|ensembl:ENST00000325404(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001649"(osteoblast differentiation)|go:"GO:0001654"(eye development)|go:"GO:0001714"(endodermal cell fate specification)|go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006325"(chromatin organization)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0009611"(response to wounding)|go:"GO:0009653"(anatomical structure morphogenesis)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0021781"(glial cell fate commitment)|go:"GO:0021983"(pituitary gland development)|go:"GO:0021984"(adenohypophysis development)|go:"GO:0022409"(positive regulation of cell-cell adhesion)|go:"GO:0030154"(cell differentiation)|go:"GO:0030900"(forebrain development)|go:"GO:0035019"(somatic stem cell population maintenance)|go:"GO:0035198"(miRNA binding)|go:"GO:0042246"(tissue regeneration)|go:"GO:0043281"(regulation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0043410"(positive regulation of MAPK cascade)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045165"(cell fate commitment)|go:"GO:0045597"(positive regulation of cell differentiation)|go:"GO:0045665"(negative regulation of neuron differentiation)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048839"(inner ear development)|go:"GO:0050680"(negative regulation of epithelial cell proliferation)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0070848"(response to growth factor)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:0097150"(neuronal stem cell population maintenance)|interpro:IPR009071(High mobility group box, HMG)|interpro:IPR022097|interpro:IPR032643|interpro:IPR036910|mint:P48431|rcsb pdb:1O4X|rcsb pdb:2LE4|rcsb pdb:6T7B|rcsb pdb:6T90|rcsb pdb:6WX7|rcsb pdb:6WX8|rcsb pdb:6WX9|rcsb pdb:6YOV|reactome:R-HSA-2892245|reactome:R-HSA-2892247|reactome:R-HSA-3769402|reactome:R-HSA-452723|reactome:R-HSA-6785807|reactome:R-HSA-8986944 ensembl:ENSG00000162775(gene)|ensembl:ENST00000369784(transcript)|ensembl:ENST00000618772(transcript)|go:"GO:0000381"(regulation of alternative mRNA splicing, via spliceosome)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0001510"(RNA methylation)|go:"GO:0001569"(branching involved in blood vessel morphogenesis)|go:"GO:0003676"(nucleic acid binding)|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0007221"(positive regulation of transcription of Notch receptor target)|go:"GO:0009048"(dosage compensation by inactivation of X chromosome)|go:"GO:0016607"(nuclear speck)|go:"GO:0031965"(nuclear membrane)|go:"GO:0036396"(RNA N6-methyladenosine methyltransferase complex)|go:"GO:0038163"(thrombopoietin-mediated signaling pathway)|go:"GO:0045638"(negative regulation of myeloid cell differentiation)|go:"GO:0045652"(regulation of megakaryocyte differentiation)|go:"GO:0048536"(spleen development)|go:"GO:0060674"(placenta blood vessel development)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR010912(Spen paralogue and orthologue C-terminal, metazoa)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR012921(Spen paralogue and orthologue C-terminal)|interpro:IPR016194(Spen Paralogue and Orthologue C-terminal-like)|interpro:IPR034470|interpro:IPR034472|interpro:IPR034473|interpro:IPR035979|mint:Q96T37|go:"GO:0060412"(ventricular septum morphogenesis)|refseq:NP_001188474.1|refseq:NP_073605.4|ensembl:ENSP00000358799|ensembl:ENST00000487146|ensembl:ENSP00000473552|ensembl:ENST00000602849|ensembl:ENSP00000473638|ensembl:ENSP00000483133|ensembl:ENST00000652342|ensembl:ENSP00000498328|ensembl:ENST00000652747|ensembl:ENSP00000498634 go:"GO:0005634"(nucleus) - - figure legend:ST3 F2C|comment:proteins that were enriched in the induced sample more than 6-fold|dataset:Brain Disease - Neurological Diseases & Disorders|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-daoy)|taxid:9606(Homo sapiens DAOY cerebellar medulloblastoma cell line) - 2020/12/29 2020/12/29 rogid:cn8gYfKDpQc8J2ygnqny32sIyyU9606 rogid:t7EkMQbmDxPl/X8yPkBi1zCywac9606 rigid:Cnhili6Os5i+9KsmWx3iqclZGC0 false tandem tag:n-n - - - psi-mi:"MI:0658"(multidimensional protein identification technology) psi-mi:"MI:0658"(multidimensional protein identification technology) uniprotkb:P48431 uniprotkb:O43172 intact:EBI-6124081|uniprotkb:Q14537|ensembl:ENSP00000323588 intact:EBI-718395|uniprotkb:O43445|uniprotkb:O43864|uniprotkb:Q96DG2|uniprotkb:Q96IK4|uniprotkb:Q5T1M8|ensembl:ENSP00000363315 psi-mi:sox2_human(display_long)|uniprotkb:SOX2(gene name)|psi-mi:SOX2(display_short) psi-mi:prp4_human(display_long)|uniprotkb:U4/U6 snRNP 60 kDa protein(gene name synonym)|uniprotkb:WD splicing factor Prp4(gene name synonym)|uniprotkb:PRP4 homolog(gene name synonym)|uniprotkb:PRPF4(gene name)|psi-mi:PRPF4(display_short)|uniprotkb:PRP4(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Cox et al. (2012) pubmed:23667531|imex:IM-28599 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-26574478|imex:IM-28599-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_003097.1|dip:DIP-59913N|ensembl:ENSG00000181449(gene)|ensembl:ENST00000325404(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001649"(osteoblast differentiation)|go:"GO:0001654"(eye development)|go:"GO:0001714"(endodermal cell fate specification)|go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006325"(chromatin organization)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0009611"(response to wounding)|go:"GO:0009653"(anatomical structure morphogenesis)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0021781"(glial cell fate commitment)|go:"GO:0021983"(pituitary gland development)|go:"GO:0021984"(adenohypophysis development)|go:"GO:0022409"(positive regulation of cell-cell adhesion)|go:"GO:0030154"(cell differentiation)|go:"GO:0030900"(forebrain development)|go:"GO:0035019"(somatic stem cell population maintenance)|go:"GO:0035198"(miRNA binding)|go:"GO:0042246"(tissue regeneration)|go:"GO:0043281"(regulation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0043410"(positive regulation of MAPK cascade)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045165"(cell fate commitment)|go:"GO:0045597"(positive regulation of cell differentiation)|go:"GO:0045665"(negative regulation of neuron differentiation)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048839"(inner ear development)|go:"GO:0050680"(negative regulation of epithelial cell proliferation)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0070848"(response to growth factor)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:0097150"(neuronal stem cell population maintenance)|interpro:IPR009071(High mobility group box, HMG)|interpro:IPR022097|interpro:IPR032643|interpro:IPR036910|mint:P48431|rcsb pdb:1O4X|rcsb pdb:2LE4|rcsb pdb:6T7B|rcsb pdb:6T90|rcsb pdb:6WX7|rcsb pdb:6WX8|rcsb pdb:6WX9|rcsb pdb:6YOV|reactome:R-HSA-2892245|reactome:R-HSA-2892247|reactome:R-HSA-3769402|reactome:R-HSA-452723|reactome:R-HSA-6785807|reactome:R-HSA-8986944 refseq:NP_004688.2|refseq:NP_001231855.1|ensembl:ENSG00000136875(gene)|ensembl:ENST00000374199(transcript)|go:"GO:0000375"(RNA splicing, via transesterification reactions)|go:"GO:0046540"(U4/U6 x U5 tri-snRNP complex)|go:"GO:0071001"(U4/U6 snRNP)|go:"GO:0071005"(U2-type precatalytic spliceosome)|go:"GO:0097525"(spliceosomal snRNP complex)|interpro:IPR001680(WD40 repeat)|interpro:IPR014906("Pre-mRNA processing factor 4 (PRP4) like")|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005681"(spliceosomal complex)|interpro:IPR015943(WD40/YVTN repeat-like)|go:"GO:0006396"(RNA processing)|go:"GO:0008380"(RNA splicing)|go:"GO:0015030"(Cajal body)|go:"GO:0016607"(nuclear speck)|go:"GO:0017070"(U6 snRNA binding)|interpro:IPR019775|interpro:IPR020472|interpro:IPR036285|interpro:IPR036322|mint:O43172|rcsb pdb:1MZW|rcsb pdb:3JCR|rcsb pdb:5O9Z|rcsb pdb:6AH0|rcsb pdb:6AHD|rcsb pdb:6QW6|rcsb pdb:6QX9|reactome:R-HSA-72163|go:"GO:0030621"(U4 snRNA binding) go:"GO:0005634"(nucleus) - - figure legend:ST3 F2C|comment:proteins that were enriched in the induced sample more than 6-fold|dataset:Brain Disease - Neurological Diseases & Disorders|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-daoy)|taxid:9606(Homo sapiens DAOY cerebellar medulloblastoma cell line) - 2020/12/29 2020/12/29 rogid:cn8gYfKDpQc8J2ygnqny32sIyyU9606 rogid:PPTNuhEFj4D+gTv/ctTTMzGmFA09606 rigid:Cnhili6Os5i+9KsmWx3iqclZGC0 false tandem tag:n-n - - - psi-mi:"MI:0658"(multidimensional protein identification technology) psi-mi:"MI:0658"(multidimensional protein identification technology) uniprotkb:P48431 uniprotkb:O60563 intact:EBI-6124081|uniprotkb:Q14537|ensembl:ENSP00000323588 intact:EBI-2479671|ensembl:ENSP00000261900|uniprotkb:O60581|uniprotkb:A9XU13|uniprotkb:E7EX76 psi-mi:sox2_human(display_long)|uniprotkb:SOX2(gene name)|psi-mi:SOX2(display_short) psi-mi:ccnt1_human(display_long)|uniprotkb:CCNT1(gene name)|psi-mi:CCNT1(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Cox et al. (2012) pubmed:23667531|imex:IM-28599 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-26574478|imex:IM-28599-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_003097.1|dip:DIP-59913N|ensembl:ENSG00000181449(gene)|ensembl:ENST00000325404(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001649"(osteoblast differentiation)|go:"GO:0001654"(eye development)|go:"GO:0001714"(endodermal cell fate specification)|go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006325"(chromatin organization)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0009611"(response to wounding)|go:"GO:0009653"(anatomical structure morphogenesis)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0021781"(glial cell fate commitment)|go:"GO:0021983"(pituitary gland development)|go:"GO:0021984"(adenohypophysis development)|go:"GO:0022409"(positive regulation of cell-cell adhesion)|go:"GO:0030154"(cell differentiation)|go:"GO:0030900"(forebrain development)|go:"GO:0035019"(somatic stem cell population maintenance)|go:"GO:0035198"(miRNA binding)|go:"GO:0042246"(tissue regeneration)|go:"GO:0043281"(regulation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0043410"(positive regulation of MAPK cascade)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045165"(cell fate commitment)|go:"GO:0045597"(positive regulation of cell differentiation)|go:"GO:0045665"(negative regulation of neuron differentiation)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048839"(inner ear development)|go:"GO:0050680"(negative regulation of epithelial cell proliferation)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0070848"(response to growth factor)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:0097150"(neuronal stem cell population maintenance)|interpro:IPR009071(High mobility group box, HMG)|interpro:IPR022097|interpro:IPR032643|interpro:IPR036910|mint:P48431|rcsb pdb:1O4X|rcsb pdb:2LE4|rcsb pdb:6T7B|rcsb pdb:6T90|rcsb pdb:6WX7|rcsb pdb:6WX8|rcsb pdb:6WX9|rcsb pdb:6YOV|reactome:R-HSA-2892245|reactome:R-HSA-2892247|reactome:R-HSA-3769402|reactome:R-HSA-452723|reactome:R-HSA-6785807|reactome:R-HSA-8986944 go:"GO:0097322"(7SK snRNA binding)|go:"GO:1900364"(negative regulation of mRNA polyadenylation)|interpro:IPR006671(Cyclin, N-terminal)|go:"GO:0070691"(P-TEFb complex)|interpro:IPR013763(Cyclin-related)|interpro:IPR028863|interpro:IPR036915|interpro:IPR043198|mint:O60563|rcsb pdb:2PK2|rcsb pdb:3BLH|rcsb pdb:3BLQ|rcsb pdb:3BLR|rcsb pdb:3LQ5|rcsb pdb:3MI9|rcsb pdb:3MIA|rcsb pdb:3MY1|rcsb pdb:3TN8|rcsb pdb:3TNH|rcsb pdb:3TNI|rcsb pdb:4BCF|rcsb pdb:4BCG|rcsb pdb:4BCH|rcsb pdb:4BCI|rcsb pdb:4BCJ|rcsb pdb:4EC8|rcsb pdb:4EC9|rcsb pdb:4IMY|rcsb pdb:4OGR|rcsb pdb:4OR5|rcsb pdb:5L1Z|rcsb pdb:6CYT|rcsb pdb:6GZH|rcsb pdb:6Z45|reactome:R-HSA-112382|reactome:R-HSA-167152|reactome:R-HSA-167200|reactome:R-HSA-167238|reactome:R-HSA-167243|reactome:R-HSA-167246|reactome:R-HSA-167287|reactome:R-HSA-167290|reactome:R-HSA-176034|reactome:R-HSA-2173796|reactome:R-HSA-674695|reactome:R-HSA-6796648|reactome:R-HSA-6807505|reactome:R-HSA-75955|reactome:R-HSA-9018519|ensembl:ENSG00000129315(gene)|ensembl:ENST00000261900(transcript)|go:"GO:0000079"(regulation of cyclin-dependent protein serine/threonine kinase activity)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0007049"(cell cycle)|go:"GO:0008024"(cyclin/CDK positive transcription elongation factor complex)|go:"GO:0008134"(transcription factor binding)|go:"GO:0016538"(cyclin-dependent protein serine/threonine kinase regulator activity)|go:"GO:0019901"(protein kinase binding)|go:"GO:0032786"(positive regulation of DNA-templated transcription, elongation)|go:"GO:0043923"(positive regulation by host of viral transcription)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0051301"(cell division)|go:"GO:0061575"(cyclin-dependent protein serine/threonine kinase activator activity)|go:"GO:0070063"(RNA polymerase binding)|refseq:NP_001231.2|refseq:NP_001264771.1|dip:DIP-29891N go:"GO:0005634"(nucleus) - - figure legend:ST3 F2C|comment:proteins that were enriched in the induced sample more than 6-fold|dataset:Brain Disease - Neurological Diseases & Disorders|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-daoy)|taxid:9606(Homo sapiens DAOY cerebellar medulloblastoma cell line) - 2020/12/29 2020/12/29 rogid:cn8gYfKDpQc8J2ygnqny32sIyyU9606 rogid:y80GILqwBbb5hMtl/4U1Y/vNx909606 rigid:Cnhili6Os5i+9KsmWx3iqclZGC0 false tandem tag:n-n - - - psi-mi:"MI:0658"(multidimensional protein identification technology) psi-mi:"MI:0658"(multidimensional protein identification technology) uniprotkb:P48431 uniprotkb:Q8TF68 intact:EBI-6124081|uniprotkb:Q14537|ensembl:ENSP00000323588 intact:EBI-6115971|uniprotkb:O15407|uniprotkb:Q7Z722|uniprotkb:Q8N938|ensembl:ENSP00000354592|ensembl:ENSP00000380019 psi-mi:sox2_human(display_long)|uniprotkb:SOX2(gene name)|psi-mi:SOX2(display_short) psi-mi:zn384_human(display_long)|uniprotkb:ZNF384(gene name)|psi-mi:ZNF384(display_short)|uniprotkb:CAGH1(gene name synonym)|uniprotkb:CIZ(gene name synonym)|uniprotkb:NMP4(gene name synonym)|uniprotkb:TNRC1(gene name synonym)|uniprotkb:CAG repeat protein 1(gene name synonym)|uniprotkb:CAS-interacting zinc finger protein(gene name synonym)|uniprotkb:Nuclear matrix transcription factor 4(gene name synonym)|uniprotkb:Trinucleotide repeat-containing gene 1 protein(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Cox et al. (2012) pubmed:23667531|imex:IM-28599 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-26574478|imex:IM-28599-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_003097.1|dip:DIP-59913N|ensembl:ENSG00000181449(gene)|ensembl:ENST00000325404(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001649"(osteoblast differentiation)|go:"GO:0001654"(eye development)|go:"GO:0001714"(endodermal cell fate specification)|go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006325"(chromatin organization)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0009611"(response to wounding)|go:"GO:0009653"(anatomical structure morphogenesis)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0021781"(glial cell fate commitment)|go:"GO:0021983"(pituitary gland development)|go:"GO:0021984"(adenohypophysis development)|go:"GO:0022409"(positive regulation of cell-cell adhesion)|go:"GO:0030154"(cell differentiation)|go:"GO:0030900"(forebrain development)|go:"GO:0035019"(somatic stem cell population maintenance)|go:"GO:0035198"(miRNA binding)|go:"GO:0042246"(tissue regeneration)|go:"GO:0043281"(regulation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0043410"(positive regulation of MAPK cascade)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045165"(cell fate commitment)|go:"GO:0045597"(positive regulation of cell differentiation)|go:"GO:0045665"(negative regulation of neuron differentiation)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048839"(inner ear development)|go:"GO:0050680"(negative regulation of epithelial cell proliferation)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0070848"(response to growth factor)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:0097150"(neuronal stem cell population maintenance)|interpro:IPR009071(High mobility group box, HMG)|interpro:IPR022097|interpro:IPR032643|interpro:IPR036910|mint:P48431|rcsb pdb:1O4X|rcsb pdb:2LE4|rcsb pdb:6T7B|rcsb pdb:6T90|rcsb pdb:6WX7|rcsb pdb:6WX8|rcsb pdb:6WX9|rcsb pdb:6YOV|reactome:R-HSA-2892245|reactome:R-HSA-2892247|reactome:R-HSA-3769402|reactome:R-HSA-452723|reactome:R-HSA-6785807|reactome:R-HSA-8986944 ensembl:ENST00000319770|ensembl:ENSP00000321650|ensembl:ENSP00000354592|ensembl:ENSP00000380019|ensembl:ENST00000355772|ensembl:ENSP00000348018|refseq:NP_001035009.1|refseq:NP_001129206.1|refseq:NP_597733.2|refseq:XP_016874430.1|refseq:XP_016874431.1|refseq:XP_016874432.1|refseq:XP_016874438.1|refseq:XP_016874439.1|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR036236|mint:Q8TF68|ensembl:ENSG00000126746(gene)|ensembl:ENST00000361959(transcript)|ensembl:ENST00000396801(transcript) go:"GO:0005634"(nucleus) - - figure legend:ST3 F2C|comment:proteins that were enriched in the induced sample more than 6-fold|dataset:Brain Disease - Neurological Diseases & Disorders|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-daoy)|taxid:9606(Homo sapiens DAOY cerebellar medulloblastoma cell line) - 2020/12/29 2020/12/29 rogid:cn8gYfKDpQc8J2ygnqny32sIyyU9606 rogid:6TO45205H9niXg8StUmIooVLC289606 rigid:Cnhili6Os5i+9KsmWx3iqclZGC0 false tandem tag:n-n - - - psi-mi:"MI:0658"(multidimensional protein identification technology) psi-mi:"MI:0658"(multidimensional protein identification technology) uniprotkb:P48431 uniprotkb:Q09028 intact:EBI-6124081|uniprotkb:Q14537|ensembl:ENSP00000323588 intact:EBI-620823|uniprotkb:B4DRH0|ensembl:ENSP00000362592|uniprotkb:P31149|uniprotkb:Q53H02|uniprotkb:Q96BV9|uniprotkb:D3DPQ3|uniprotkb:B2R6G9 psi-mi:sox2_human(display_long)|uniprotkb:SOX2(gene name)|psi-mi:SOX2(display_short) psi-mi:rbbp4_human(display_long)|uniprotkb:Retinoblastoma-binding protein 4(gene name synonym)|uniprotkb:Retinoblastoma-binding protein p48(gene name synonym)|uniprotkb:Chromatin assembly factor 1 subunit C(gene name synonym)|uniprotkb:Chromatin assembly factor I p48 subunit(gene name synonym)|uniprotkb:Nucleosome-remodeling factor subunit RBAP48(gene name synonym)|uniprotkb:RBBP4(gene name)|psi-mi:RBBP4(display_short)|uniprotkb:RBAP48(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Cox et al. (2012) pubmed:23667531|imex:IM-28599 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-26574478|imex:IM-28599-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_003097.1|dip:DIP-59913N|ensembl:ENSG00000181449(gene)|ensembl:ENST00000325404(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001649"(osteoblast differentiation)|go:"GO:0001654"(eye development)|go:"GO:0001714"(endodermal cell fate specification)|go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006325"(chromatin organization)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0009611"(response to wounding)|go:"GO:0009653"(anatomical structure morphogenesis)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0021781"(glial cell fate commitment)|go:"GO:0021983"(pituitary gland development)|go:"GO:0021984"(adenohypophysis development)|go:"GO:0022409"(positive regulation of cell-cell adhesion)|go:"GO:0030154"(cell differentiation)|go:"GO:0030900"(forebrain development)|go:"GO:0035019"(somatic stem cell population maintenance)|go:"GO:0035198"(miRNA binding)|go:"GO:0042246"(tissue regeneration)|go:"GO:0043281"(regulation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0043410"(positive regulation of MAPK cascade)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045165"(cell fate commitment)|go:"GO:0045597"(positive regulation of cell differentiation)|go:"GO:0045665"(negative regulation of neuron differentiation)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048839"(inner ear development)|go:"GO:0050680"(negative regulation of epithelial cell proliferation)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0070848"(response to growth factor)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:0097150"(neuronal stem cell population maintenance)|interpro:IPR009071(High mobility group box, HMG)|interpro:IPR022097|interpro:IPR032643|interpro:IPR036910|mint:P48431|rcsb pdb:1O4X|rcsb pdb:2LE4|rcsb pdb:6T7B|rcsb pdb:6T90|rcsb pdb:6WX7|rcsb pdb:6WX8|rcsb pdb:6WX9|rcsb pdb:6YOV|reactome:R-HSA-2892245|reactome:R-HSA-2892247|reactome:R-HSA-3769402|reactome:R-HSA-452723|reactome:R-HSA-6785807|reactome:R-HSA-8986944 ensembl:ENSG00000162521(gene)|ensembl:ENST00000373493(transcript)|go:"GO:0000118"(histone deacetylase complex)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006260"(DNA replication)|go:"GO:0006335"(DNA replication-dependent chromatin assembly)|go:"GO:0006336"(DNA replication-independent chromatin assembly)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0007049"(cell cycle)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0016580"(Sin3 complex)|go:"GO:0016581"(NuRD complex)|go:"GO:0016589"(NURF complex)|go:"GO:0031497"(chromatin assembly)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033186"(CAF-1 complex)|go:"GO:0035098"("ESC/E(Z) complex")|go:"GO:0042393"(histone binding)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0043044"|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019775|interpro:IPR020472|interpro:IPR022052|mint:Q09028|rcsb pdb:2XU7|rcsb pdb:3GFC|rcsb pdb:4PBY|rcsb pdb:4PBZ|rcsb pdb:4PC0|rcsb pdb:4R7A|rcsb pdb:5FXY|rcsb pdb:5VTB|rcsb pdb:5WAI|rcsb pdb:5WAK|rcsb pdb:5XWR|rcsb pdb:5XXQ|rcsb pdb:5Y1U|rcsb pdb:6BW3|rcsb pdb:6BW4|rcsb pdb:6C23|rcsb pdb:6C24|rcsb pdb:6G16|rcsb pdb:6NQ3|rcsb pdb:6WKR|rcsb pdb:6ZRC|rcsb pdb:6ZRD|rcsb pdb:7AOA|rcsb pdb:7KSO|rcsb pdb:7KSR|rcsb pdb:7KTP|rcsb pdb:7M40|reactome:R-HSA-1362277|reactome:R-HSA-1362300|reactome:R-HSA-1538133|reactome:R-HSA-156711|reactome:R-HSA-212300|reactome:R-HSA-2559580|reactome:R-HSA-3214815|reactome:R-HSA-3214841|reactome:R-HSA-427389|reactome:R-HSA-5617472|reactome:R-HSA-606279|reactome:R-HSA-6804758|reactome:R-HSA-69202|reactome:R-HSA-69205|reactome:R-HSA-69656|reactome:R-HSA-73762|reactome:R-HSA-8943724|reactome:R-HSA-8953750|reactome:R-HSA-9609690|reactome:R-HSA-9679191|reactome:R-HSA-9710421|interpro:IPR036322|refseq:NP_001128727.1|refseq:NP_001128728.1|refseq:NP_005601.1|dip:DIP-33495N go:"GO:0005634"(nucleus) - - figure legend:ST3 F2C|comment:proteins that were enriched in the induced sample more than 6-fold|dataset:Brain Disease - Neurological Diseases & Disorders|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-daoy)|taxid:9606(Homo sapiens DAOY cerebellar medulloblastoma cell line) - 2020/12/29 2020/12/29 rogid:cn8gYfKDpQc8J2ygnqny32sIyyU9606 rogid:CbyJMIjpW1A4sZijP0IGRYc8o4I9606 rigid:Cnhili6Os5i+9KsmWx3iqclZGC0 false tandem tag:n-n - - - psi-mi:"MI:0658"(multidimensional protein identification technology) psi-mi:"MI:0658"(multidimensional protein identification technology) uniprotkb:P48431 uniprotkb:Q9BYD3 intact:EBI-6124081|uniprotkb:Q14537|ensembl:ENSP00000323588 intact:EBI-721368|uniprotkb:A6NNV7|uniprotkb:Q9BW07|uniprotkb:Q9H4N2|uniprotkb:Q9Y317|ensembl:ENSP00000253099|ensembl:ENSP00000306902 psi-mi:sox2_human(display_long)|uniprotkb:SOX2(gene name)|psi-mi:SOX2(display_short) psi-mi:rm04_human(display_long)|uniprotkb:MRPL4(gene name)|psi-mi:MRPL4(display_short)|uniprotkb:Mitochondrial large ribosomal subunit protein uL4m(gene name synonym)|uniprotkb:CDABP0091(orf name)|uniprotkb:CGI-28(orf name) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Cox et al. (2012) pubmed:23667531|imex:IM-28599 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-26574478|imex:IM-28599-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_003097.1|dip:DIP-59913N|ensembl:ENSG00000181449(gene)|ensembl:ENST00000325404(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001649"(osteoblast differentiation)|go:"GO:0001654"(eye development)|go:"GO:0001714"(endodermal cell fate specification)|go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006325"(chromatin organization)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0009611"(response to wounding)|go:"GO:0009653"(anatomical structure morphogenesis)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0021781"(glial cell fate commitment)|go:"GO:0021983"(pituitary gland development)|go:"GO:0021984"(adenohypophysis development)|go:"GO:0022409"(positive regulation of cell-cell adhesion)|go:"GO:0030154"(cell differentiation)|go:"GO:0030900"(forebrain development)|go:"GO:0035019"(somatic stem cell population maintenance)|go:"GO:0035198"(miRNA binding)|go:"GO:0042246"(tissue regeneration)|go:"GO:0043281"(regulation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0043410"(positive regulation of MAPK cascade)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045165"(cell fate commitment)|go:"GO:0045597"(positive regulation of cell differentiation)|go:"GO:0045665"(negative regulation of neuron differentiation)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048839"(inner ear development)|go:"GO:0050680"(negative regulation of epithelial cell proliferation)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0070848"(response to growth factor)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:0097150"(neuronal stem cell population maintenance)|interpro:IPR009071(High mobility group box, HMG)|interpro:IPR022097|interpro:IPR032643|interpro:IPR036910|mint:P48431|rcsb pdb:1O4X|rcsb pdb:2LE4|rcsb pdb:6T7B|rcsb pdb:6T90|rcsb pdb:6WX7|rcsb pdb:6WX8|rcsb pdb:6WX9|rcsb pdb:6YOV|reactome:R-HSA-2892245|reactome:R-HSA-2892247|reactome:R-HSA-3769402|reactome:R-HSA-452723|reactome:R-HSA-6785807|reactome:R-HSA-8986944 refseq:NP_057040.2|refseq:NP_666499.1|refseq:NP_666500.1|ensembl:ENSG00000105364(gene)|ensembl:ENST00000253099(transcript)|ensembl:ENST00000307422(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005762"(mitochondrial large ribosomal subunit)|go:"GO:0006412"(translation)|interpro:IPR002136(Ribosomal protein L4/L1e)|interpro:IPR013005(Ribosomal protein L4/L1e, bacterial-type)|interpro:IPR023574|mint:Q9BYD3|rcsb pdb:3J7Y|rcsb pdb:3J9M|rcsb pdb:5OOL|rcsb pdb:7O9K|rcsb pdb:7O9M|rcsb pdb:7ODR|rcsb pdb:7ODS|rcsb pdb:7ODT|rcsb pdb:7OF0|rcsb pdb:7OF2|rcsb pdb:7OF3|rcsb pdb:7OF4|rcsb pdb:7OF5|rcsb pdb:7OF6|rcsb pdb:7OF7|rcsb pdb:7OG4|reactome:R-HSA-5368286|reactome:R-HSA-5389840|reactome:R-HSA-5419276|rcsb pdb:5OOM|rcsb pdb:6I9R|rcsb pdb:6NU2|rcsb pdb:6NU3|rcsb pdb:6VLZ|rcsb pdb:6VMI|rcsb pdb:6ZM5|rcsb pdb:6ZM6|rcsb pdb:6ZS9|rcsb pdb:6ZSA|rcsb pdb:6ZSB|rcsb pdb:6ZSC|rcsb pdb:6ZSD|rcsb pdb:6ZSE|rcsb pdb:6ZSG|rcsb pdb:7A5F|rcsb pdb:7A5G|rcsb pdb:7A5H|rcsb pdb:7A5I|rcsb pdb:7A5J|rcsb pdb:7A5K|rcsb pdb:7L08|rcsb pdb:7L20 go:"GO:0005634"(nucleus) - - figure legend:ST3 F2C|comment:proteins that were enriched in the induced sample more than 6-fold|dataset:Brain Disease - Neurological Diseases & Disorders|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-daoy)|taxid:9606(Homo sapiens DAOY cerebellar medulloblastoma cell line) - 2020/12/29 2020/12/29 rogid:cn8gYfKDpQc8J2ygnqny32sIyyU9606 rogid:v1MODeAQQcG4MKCE/hvEg2NBwmk9606 rigid:Cnhili6Os5i+9KsmWx3iqclZGC0 false tandem tag:n-n - - - psi-mi:"MI:0658"(multidimensional protein identification technology) psi-mi:"MI:0658"(multidimensional protein identification technology) uniprotkb:P48431 uniprotkb:Q71U36 intact:EBI-6124081|uniprotkb:Q14537|ensembl:ENSP00000323588 intact:EBI-302552|uniprotkb:P04687|uniprotkb:P05209|uniprotkb:A8K0B8|uniprotkb:G3V1U9|intact:EBI-10989786|ensembl:ENSP00000301071|ensembl:ENSP00000439020 psi-mi:sox2_human(display_long)|uniprotkb:SOX2(gene name)|psi-mi:SOX2(display_short) psi-mi:tba1a_human(display_long)|uniprotkb:TUBA1A(gene name)|psi-mi:TUBA1A(display_short)|uniprotkb:Tubulin B-alpha-1(gene name synonym)|uniprotkb:Tubulin alpha-3 chain(gene name synonym)|uniprotkb:Alpha-tubulin 3(gene name synonym)|uniprotkb:TUBA3(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Cox et al. (2012) pubmed:23667531|imex:IM-28599 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-26574478|imex:IM-28599-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_003097.1|dip:DIP-59913N|ensembl:ENSG00000181449(gene)|ensembl:ENST00000325404(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001649"(osteoblast differentiation)|go:"GO:0001654"(eye development)|go:"GO:0001714"(endodermal cell fate specification)|go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006325"(chromatin organization)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0009611"(response to wounding)|go:"GO:0009653"(anatomical structure morphogenesis)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0021781"(glial cell fate commitment)|go:"GO:0021983"(pituitary gland development)|go:"GO:0021984"(adenohypophysis development)|go:"GO:0022409"(positive regulation of cell-cell adhesion)|go:"GO:0030154"(cell differentiation)|go:"GO:0030900"(forebrain development)|go:"GO:0035019"(somatic stem cell population maintenance)|go:"GO:0035198"(miRNA binding)|go:"GO:0042246"(tissue regeneration)|go:"GO:0043281"(regulation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0043410"(positive regulation of MAPK cascade)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045165"(cell fate commitment)|go:"GO:0045597"(positive regulation of cell differentiation)|go:"GO:0045665"(negative regulation of neuron differentiation)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048839"(inner ear development)|go:"GO:0050680"(negative regulation of epithelial cell proliferation)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0070848"(response to growth factor)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:0097150"(neuronal stem cell population maintenance)|interpro:IPR009071(High mobility group box, HMG)|interpro:IPR022097|interpro:IPR032643|interpro:IPR036910|mint:P48431|rcsb pdb:1O4X|rcsb pdb:2LE4|rcsb pdb:6T7B|rcsb pdb:6T90|rcsb pdb:6WX7|rcsb pdb:6WX8|rcsb pdb:6WX9|rcsb pdb:6YOV|reactome:R-HSA-2892245|reactome:R-HSA-2892247|reactome:R-HSA-3769402|reactome:R-HSA-452723|reactome:R-HSA-6785807|reactome:R-HSA-8986944 refseq:NP_006000.2|refseq:NP_001257328.1|refseq:NP_001257329.1|dip:DIP-32773N|ensembl:ENSG00000167552(gene)|ensembl:ENST00000295766(transcript)|ensembl:ENST00000301071(transcript)|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005200"(structural constituent of cytoskeleton)|go:"GO:0005525"(GTP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005874"(microtubule)|go:"GO:0005881"(cytoplasmic microtubule)|go:"GO:0007017"(microtubule-based process)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030705"(cytoskeleton-dependent intracellular transport)|go:"GO:0031594"(neuromuscular junction)|go:"GO:0036464"(cytoplasmic ribonucleoprotein granule)|go:"GO:0042802"(identical protein binding)|go:"GO:0043209"(myelin sheath)|go:"GO:0045121"(membrane raft)|go:"GO:0050807"(regulation of synapse organization)|go:"GO:0051301"(cell division)|go:"GO:0055037"(recycling endosome)|go:"GO:0070062"(extracellular exosome)|interpro:IPR000217(Tubulin)|interpro:IPR002452(Alpha tubulin)|interpro:IPR003008(Tubulin/FtsZ, GTPase)|interpro:IPR008280(Tubulin/FtsZ, C-terminal)|interpro:IPR017975|interpro:IPR018316|interpro:IPR023123|interpro:IPR036525|interpro:IPR037103|mint:Q71U36|rcsb pdb:5JCO|rcsb pdb:6J8F|rcsb pdb:6WSL|rcsb pdb:7C1M|reactome:R-HSA-1445148|reactome:R-HSA-9646399|reactome:R-HSA-9648025|reactome:R-HSA-9668328|reactome:R-HSA-983189|reactome:R-HSA-190840|reactome:R-HSA-190861|reactome:R-HSA-2132295|reactome:R-HSA-2467813|reactome:R-HSA-2500257|reactome:R-HSA-2565942|reactome:R-HSA-3371497|reactome:R-HSA-380259|reactome:R-HSA-380270|reactome:R-HSA-380284|reactome:R-HSA-380320|reactome:R-HSA-389957|reactome:R-HSA-389960|reactome:R-HSA-389977|reactome:R-HSA-437239|reactome:R-HSA-5610787|reactome:R-HSA-5617833|reactome:R-HSA-5620912|reactome:R-HSA-5620924|reactome:R-HSA-5626467|reactome:R-HSA-5663220|reactome:R-HSA-6807878|reactome:R-HSA-6811434|reactome:R-HSA-6811436|reactome:R-HSA-68877|reactome:R-HSA-8852276|reactome:R-HSA-8854518|reactome:R-HSA-8955332|reactome:R-HSA-9609690|reactome:R-HSA-9609736|reactome:R-HSA-9619483 go:"GO:0005634"(nucleus) - - figure legend:ST3 F2C|comment:proteins that were enriched in the induced sample more than 6-fold|dataset:Brain Disease - Neurological Diseases & Disorders|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-daoy)|taxid:9606(Homo sapiens DAOY cerebellar medulloblastoma cell line) - 2020/12/29 2020/12/29 rogid:cn8gYfKDpQc8J2ygnqny32sIyyU9606 rogid:1CzEzrf5y8hrQRPKgWQS1Wm1aCY9606 rigid:Cnhili6Os5i+9KsmWx3iqclZGC0 false tandem tag:n-n - - - psi-mi:"MI:0658"(multidimensional protein identification technology) psi-mi:"MI:0658"(multidimensional protein identification technology) uniprotkb:P48431 uniprotkb:Q6PKG0 intact:EBI-6124081|uniprotkb:Q14537|ensembl:ENSP00000323588 intact:EBI-1052114|uniprotkb:O94836|uniprotkb:Q8N4M2|uniprotkb:Q8NB73|uniprotkb:Q9UFD7|ensembl:ENSP00000428589 psi-mi:sox2_human(display_long)|uniprotkb:SOX2(gene name)|psi-mi:SOX2(display_short) psi-mi:larp1_human(display_long)|uniprotkb:La ribonucleoprotein domain family member 1(gene name synonym)|uniprotkb:LARP1(gene name)|psi-mi:LARP1(display_short)|uniprotkb:KIAA0731(gene name synonym)|uniprotkb:LARP(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Cox et al. (2012) pubmed:23667531|imex:IM-28599 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-26574478|imex:IM-28599-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_003097.1|dip:DIP-59913N|ensembl:ENSG00000181449(gene)|ensembl:ENST00000325404(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001649"(osteoblast differentiation)|go:"GO:0001654"(eye development)|go:"GO:0001714"(endodermal cell fate specification)|go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006325"(chromatin organization)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0009611"(response to wounding)|go:"GO:0009653"(anatomical structure morphogenesis)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0021781"(glial cell fate commitment)|go:"GO:0021983"(pituitary gland development)|go:"GO:0021984"(adenohypophysis development)|go:"GO:0022409"(positive regulation of cell-cell adhesion)|go:"GO:0030154"(cell differentiation)|go:"GO:0030900"(forebrain development)|go:"GO:0035019"(somatic stem cell population maintenance)|go:"GO:0035198"(miRNA binding)|go:"GO:0042246"(tissue regeneration)|go:"GO:0043281"(regulation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0043410"(positive regulation of MAPK cascade)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045165"(cell fate commitment)|go:"GO:0045597"(positive regulation of cell differentiation)|go:"GO:0045665"(negative regulation of neuron differentiation)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048839"(inner ear development)|go:"GO:0050680"(negative regulation of epithelial cell proliferation)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0070848"(response to growth factor)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:0097150"(neuronal stem cell population maintenance)|interpro:IPR009071(High mobility group box, HMG)|interpro:IPR022097|interpro:IPR032643|interpro:IPR036910|mint:P48431|rcsb pdb:1O4X|rcsb pdb:2LE4|rcsb pdb:6T7B|rcsb pdb:6T90|rcsb pdb:6WX7|rcsb pdb:6WX8|rcsb pdb:6WX9|rcsb pdb:6YOV|reactome:R-HSA-2892245|reactome:R-HSA-2892247|reactome:R-HSA-3769402|reactome:R-HSA-452723|reactome:R-HSA-6785807|reactome:R-HSA-8986944 refseq:NP_056130.2|ensembl:ENST00000336314|ensembl:ENSP00000336721|ensembl:ENSP00000428589|refseq:XP_005268461.1|ensembl:ENSG00000155506(gene)|ensembl:ENST00000518297(transcript)|go:"GO:0000339"(RNA cap binding)|go:"GO:0000340"(RNA 7-methylguanosine cap binding)|go:"GO:0003723"(RNA binding)|go:"GO:0003730"(mRNA 3'-UTR binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0006413"(translational initiation)|go:"GO:0008190"(eukaryotic initiation factor 4E binding)|go:"GO:0008283"(cell population proliferation)|go:"GO:0008494"(translation activator activity)|go:"GO:0010494"(cytoplasmic stress granule)|go:"GO:0010608"(posttranscriptional regulation of gene expression)|go:"GO:0016020"(membrane)|go:"GO:0016239"(positive regulation of macroautophagy)|go:"GO:0017148"(negative regulation of translation)|go:"GO:0031369"(translation initiation factor binding)|go:"GO:0031929"(TOR signaling)|go:"GO:0038202"(TORC1 signaling)|go:"GO:0043024"(ribosomal small subunit binding)|go:"GO:0045070"(positive regulation of viral genome replication)|go:"GO:0045296"(cadherin binding)|go:"GO:0045947"(negative regulation of translational initiation)|go:"GO:0045948"(positive regulation of translational initiation)|go:"GO:0048027"(mRNA 5'-UTR binding)|go:"GO:0048255"(mRNA stabilization)|go:"GO:0072752"(cellular response to rapamycin)|go:"GO:1990928"(response to amino acid starvation)|interpro:IPR006607(Protein of unknown function DM15)|interpro:IPR006630(RNA-binding protein Lupus La)|interpro:IPR036388|interpro:IPR036390|mint:Q6PKG0|rcsb pdb:4ZC4|rcsb pdb:5C0V|rcsb pdb:5V4R|rcsb pdb:5V7C|rcsb pdb:5V87|rcsb pdb:6PW3 go:"GO:0005634"(nucleus) - - figure legend:ST3 F2C|comment:proteins that were enriched in the induced sample more than 6-fold|dataset:Brain Disease - Neurological Diseases & Disorders|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-daoy)|taxid:9606(Homo sapiens DAOY cerebellar medulloblastoma cell line) - 2020/12/29 2020/12/29 rogid:cn8gYfKDpQc8J2ygnqny32sIyyU9606 rogid:TjQrZVRN3opAdFIWZtaEopFZf8I9606 rigid:Cnhili6Os5i+9KsmWx3iqclZGC0 false tandem tag:n-n - - - psi-mi:"MI:0658"(multidimensional protein identification technology) psi-mi:"MI:0658"(multidimensional protein identification technology) uniprotkb:P48431 uniprotkb:Q99714 intact:EBI-6124081|uniprotkb:Q14537|ensembl:ENSP00000323588 intact:EBI-79964|ensembl:ENSP00000168216|uniprotkb:Q8TCV9|uniprotkb:Q96HD5|uniprotkb:Q5H927|uniprotkb:Q6IBS9 psi-mi:sox2_human(display_long)|uniprotkb:SOX2(gene name)|psi-mi:SOX2(display_short) psi-mi:hcd2_human(display_long)|uniprotkb:HSD17B10(gene name)|psi-mi:HSD17B10(display_short)|uniprotkb:SCHAD(gene name synonym)|uniprotkb:XH98G2(gene name synonym)|uniprotkb:HADH2(gene name synonym)|uniprotkb:3-hydroxyacyl-CoA dehydrogenase type II(gene name synonym)|uniprotkb:Type II HADH(gene name synonym)|uniprotkb:3-hydroxy-2-methylbutyryl-CoA dehydrogenase(gene name synonym)|uniprotkb:Endoplasmic reticulum-associated amyloid beta-peptide-binding protein(gene name synonym)|uniprotkb:Short-chain type dehydrogenase/reductase XH98G2(gene name synonym)|uniprotkb:Mitochondrial ribonuclease P protein 2(gene name synonym)|uniprotkb:2-methyl-3-hydroxybutyryl-CoA dehydrogenase(gene name synonym)|uniprotkb:ERAB(gene name synonym)|uniprotkb:MRPP2(gene name synonym)|uniprotkb:SDR5C1(gene name synonym)|uniprotkb:Short chain dehydrogenase/reductase family 5C member 1(gene name synonym)|uniprotkb:17-beta-estradiol 17-dehydrogenase(gene name synonym)|uniprotkb:"3-alpha-(17-beta)-hydroxysteroid dehydrogenase (NAD(+))"(gene name synonym)|uniprotkb:"3alpha(or 20beta)-hydroxysteroid dehydrogenase"(gene name synonym)|uniprotkb:7-alpha-hydroxysteroid dehydrogenase(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Cox et al. (2012) pubmed:23667531|imex:IM-28599 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-26574478|imex:IM-28599-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_003097.1|dip:DIP-59913N|ensembl:ENSG00000181449(gene)|ensembl:ENST00000325404(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001649"(osteoblast differentiation)|go:"GO:0001654"(eye development)|go:"GO:0001714"(endodermal cell fate specification)|go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006325"(chromatin organization)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0009611"(response to wounding)|go:"GO:0009653"(anatomical structure morphogenesis)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0021781"(glial cell fate commitment)|go:"GO:0021983"(pituitary gland development)|go:"GO:0021984"(adenohypophysis development)|go:"GO:0022409"(positive regulation of cell-cell adhesion)|go:"GO:0030154"(cell differentiation)|go:"GO:0030900"(forebrain development)|go:"GO:0035019"(somatic stem cell population maintenance)|go:"GO:0035198"(miRNA binding)|go:"GO:0042246"(tissue regeneration)|go:"GO:0043281"(regulation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0043410"(positive regulation of MAPK cascade)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045165"(cell fate commitment)|go:"GO:0045597"(positive regulation of cell differentiation)|go:"GO:0045665"(negative regulation of neuron differentiation)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048839"(inner ear development)|go:"GO:0050680"(negative regulation of epithelial cell proliferation)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0070848"(response to growth factor)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:0097150"(neuronal stem cell population maintenance)|interpro:IPR009071(High mobility group box, HMG)|interpro:IPR022097|interpro:IPR032643|interpro:IPR036910|mint:P48431|rcsb pdb:1O4X|rcsb pdb:2LE4|rcsb pdb:6T7B|rcsb pdb:6T90|rcsb pdb:6WX7|rcsb pdb:6WX8|rcsb pdb:6WX9|rcsb pdb:6YOV|reactome:R-HSA-2892245|reactome:R-HSA-2892247|reactome:R-HSA-3769402|reactome:R-HSA-452723|reactome:R-HSA-6785807|reactome:R-HSA-8986944 rcsb pdb:2O23|reactome:R-HSA-6785470|reactome:R-HSA-6787450|reactome:R-HSA-70895|reactome:R-HSA-8868766|ensembl:ENSG00000072506(gene)|ensembl:ENST00000168216(transcript)|go:"GO:0000049"(tRNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0003857"(3-hydroxyacyl-CoA dehydrogenase activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0005886"(plasma membrane)|go:"GO:0006550"(isoleucine catabolic process)|go:"GO:0006629"(lipid metabolic process)|go:"GO:0006635"(fatty acid beta-oxidation)|go:"GO:0006699"(bile acid biosynthetic process)|go:"GO:0007005"(mitochondrion organization)|go:"GO:0008207"(C21-steroid hormone metabolic process)|go:"GO:0008209"(androgen metabolic process)|go:"GO:0008210"(estrogen metabolic process)|go:"GO:0008709"(cholate 7-alpha-dehydrogenase activity)|go:"GO:0030283"("testosterone dehydrogenase [NAD(P)] activity")|go:"GO:0030678"(mitochondrial ribonuclease P complex)|go:"GO:0042645"(mitochondrial nucleoid)|go:"GO:0044594"("17-beta-hydroxysteroid dehydrogenase (NAD+) activity")|go:"GO:0047015"(3-hydroxy-2-methylbutyryl-CoA dehydrogenase activity)|go:"GO:0047035"("testosterone dehydrogenase (NAD+) activity")|go:"GO:0047044"(androstan-3-alpha,17-beta-diol dehydrogenase activity)|go:"GO:0051289"(protein homotetramerization)|go:"GO:0062173"(brexanolone metabolic process)|go:"GO:0070901"(mitochondrial tRNA methylation)|go:"GO:0097745"(mitochondrial tRNA 5'-end processing)|go:"GO:0106281"("chenodeoxycholate 7-alpha-dehydrogenase (NAD+) activity")|go:"GO:0106282"("isoursodeoxycholate 7-beta-dehydrogenase (NAD+) activity")|go:"GO:0106283"("ursodeoxycholate 7-beta-dehydrogenase (NAD+) activity")|go:"GO:1990180"(mitochondrial tRNA 3'-end processing)|interpro:IPR002347(Glucose/ribitol dehydrogenase)|interpro:IPR020904|interpro:IPR036291|mint:Q99714|rcsb pdb:1F67|rcsb pdb:1SO8|rcsb pdb:1U7T|refseq:NP_001032900.1|refseq:NP_004484.1 go:"GO:0005634"(nucleus) - - figure legend:ST3 F2C|comment:proteins that were enriched in the induced sample more than 6-fold|dataset:Brain Disease - Neurological Diseases & Disorders|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-daoy)|taxid:9606(Homo sapiens DAOY cerebellar medulloblastoma cell line) - 2020/12/29 2020/12/29 rogid:cn8gYfKDpQc8J2ygnqny32sIyyU9606 rogid:q6/pRFyay7gQ6bb2rzvKYgfkeaE9606 rigid:Cnhili6Os5i+9KsmWx3iqclZGC0 false tandem tag:n-n - - - psi-mi:"MI:0658"(multidimensional protein identification technology) psi-mi:"MI:0658"(multidimensional protein identification technology) uniprotkb:P48431 uniprotkb:Q3ZCM7 intact:EBI-6124081|uniprotkb:Q14537|ensembl:ENSP00000323588 intact:EBI-302558|ensembl:ENSP00000456206|intact:EBI-1390656|uniprotkb:Q5SQX9|uniprotkb:Q8WZ78 psi-mi:sox2_human(display_long)|uniprotkb:SOX2(gene name)|psi-mi:SOX2(display_short) psi-mi:tbb8_human(display_long)|uniprotkb:TUBB8(gene name)|psi-mi:TUBB8(display_short)|uniprotkb:Tubulin beta 8 class VIII(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Cox et al. (2012) pubmed:23667531|imex:IM-28599 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-26574478|imex:IM-28599-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_003097.1|dip:DIP-59913N|ensembl:ENSG00000181449(gene)|ensembl:ENST00000325404(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001649"(osteoblast differentiation)|go:"GO:0001654"(eye development)|go:"GO:0001714"(endodermal cell fate specification)|go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006325"(chromatin organization)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0009611"(response to wounding)|go:"GO:0009653"(anatomical structure morphogenesis)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0021781"(glial cell fate commitment)|go:"GO:0021983"(pituitary gland development)|go:"GO:0021984"(adenohypophysis development)|go:"GO:0022409"(positive regulation of cell-cell adhesion)|go:"GO:0030154"(cell differentiation)|go:"GO:0030900"(forebrain development)|go:"GO:0035019"(somatic stem cell population maintenance)|go:"GO:0035198"(miRNA binding)|go:"GO:0042246"(tissue regeneration)|go:"GO:0043281"(regulation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0043410"(positive regulation of MAPK cascade)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045165"(cell fate commitment)|go:"GO:0045597"(positive regulation of cell differentiation)|go:"GO:0045665"(negative regulation of neuron differentiation)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048839"(inner ear development)|go:"GO:0050680"(negative regulation of epithelial cell proliferation)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0070848"(response to growth factor)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:0097150"(neuronal stem cell population maintenance)|interpro:IPR009071(High mobility group box, HMG)|interpro:IPR022097|interpro:IPR032643|interpro:IPR036910|mint:P48431|rcsb pdb:1O4X|rcsb pdb:2LE4|rcsb pdb:6T7B|rcsb pdb:6T90|rcsb pdb:6WX7|rcsb pdb:6WX8|rcsb pdb:6WX9|rcsb pdb:6YOV|reactome:R-HSA-2892245|reactome:R-HSA-2892247|reactome:R-HSA-3769402|reactome:R-HSA-452723|reactome:R-HSA-6785807|reactome:R-HSA-8986944 reactome:R-HSA-9646399|reactome:R-HSA-9648025|reactome:R-HSA-9668328|reactome:R-HSA-983189|reactome:R-HSA-9619483|ensembl:ENSG00000261456(gene)|ensembl:ENST00000568584(transcript)|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0001556"(oocyte maturation)|go:"GO:0005200"(structural constituent of cytoskeleton)|go:"GO:0005525"(GTP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005874"(microtubule)|go:"GO:0007056"(spindle assembly involved in female meiosis)|go:"GO:0070062"(extracellular exosome)|go:"GO:0072687"(meiotic spindle)|interpro:IPR000217(Tubulin)|interpro:IPR002453(Beta tubulin)|interpro:IPR003008(Tubulin/FtsZ, GTPase)|interpro:IPR008280(Tubulin/FtsZ, C-terminal)|interpro:IPR013838(Beta tubulin, autoregulation binding site)|interpro:IPR017975|interpro:IPR018316|interpro:IPR023123|interpro:IPR036525|interpro:IPR037103|mint:Q3ZCM7|reactome:R-HSA-1445148|reactome:R-HSA-190840|reactome:R-HSA-190861|reactome:R-HSA-2132295|reactome:R-HSA-2467813|reactome:R-HSA-2500257|reactome:R-HSA-3371497|reactome:R-HSA-380320|reactome:R-HSA-437239|reactome:R-HSA-5617833|reactome:R-HSA-5626467|reactome:R-HSA-5663220|reactome:R-HSA-6807878|reactome:R-HSA-6811434|reactome:R-HSA-6811436|reactome:R-HSA-68877|reactome:R-HSA-8852276|reactome:R-HSA-8955332|reactome:R-HSA-9609690|reactome:R-HSA-9609736|refseq:NP_817124.1 go:"GO:0005634"(nucleus) - - figure legend:ST3 F2C|comment:proteins that were enriched in the induced sample more than 6-fold|dataset:Brain Disease - Neurological Diseases & Disorders|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-daoy)|taxid:9606(Homo sapiens DAOY cerebellar medulloblastoma cell line) - 2020/12/29 2020/12/29 rogid:cn8gYfKDpQc8J2ygnqny32sIyyU9606 rogid:bTJnhl0qEm2ACoHQ7IOcn5Rx7xM9606 rigid:Cnhili6Os5i+9KsmWx3iqclZGC0 false tandem tag:n-n - - - psi-mi:"MI:0658"(multidimensional protein identification technology) psi-mi:"MI:0658"(multidimensional protein identification technology) uniprotkb:P48431 uniprotkb:Q8N1G0 intact:EBI-6124081|uniprotkb:Q14537|ensembl:ENSP00000323588 intact:EBI-1210558|uniprotkb:Q68DQ8|uniprotkb:Q9H937|uniprotkb:Q9P2A7|uniprotkb:D3DV17|ensembl:ENSP00000319829|ensembl:ENSP00000336620 psi-mi:sox2_human(display_long)|uniprotkb:SOX2(gene name)|psi-mi:SOX2(display_short) psi-mi:zn687_human(display_long)|uniprotkb:ZNF687(gene name)|psi-mi:ZNF687(display_short)|uniprotkb:KIAA1441(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Cox et al. (2012) pubmed:23667531|imex:IM-28599 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-26574478|imex:IM-28599-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_003097.1|dip:DIP-59913N|ensembl:ENSG00000181449(gene)|ensembl:ENST00000325404(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001649"(osteoblast differentiation)|go:"GO:0001654"(eye development)|go:"GO:0001714"(endodermal cell fate specification)|go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006325"(chromatin organization)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0009611"(response to wounding)|go:"GO:0009653"(anatomical structure morphogenesis)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0021781"(glial cell fate commitment)|go:"GO:0021983"(pituitary gland development)|go:"GO:0021984"(adenohypophysis development)|go:"GO:0022409"(positive regulation of cell-cell adhesion)|go:"GO:0030154"(cell differentiation)|go:"GO:0030900"(forebrain development)|go:"GO:0035019"(somatic stem cell population maintenance)|go:"GO:0035198"(miRNA binding)|go:"GO:0042246"(tissue regeneration)|go:"GO:0043281"(regulation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0043410"(positive regulation of MAPK cascade)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045165"(cell fate commitment)|go:"GO:0045597"(positive regulation of cell differentiation)|go:"GO:0045665"(negative regulation of neuron differentiation)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048839"(inner ear development)|go:"GO:0050680"(negative regulation of epithelial cell proliferation)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0070848"(response to growth factor)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:0097150"(neuronal stem cell population maintenance)|interpro:IPR009071(High mobility group box, HMG)|interpro:IPR022097|interpro:IPR032643|interpro:IPR036910|mint:P48431|rcsb pdb:1O4X|rcsb pdb:2LE4|rcsb pdb:6T7B|rcsb pdb:6T90|rcsb pdb:6WX7|rcsb pdb:6WX8|rcsb pdb:6WX9|rcsb pdb:6YOV|reactome:R-HSA-2892245|reactome:R-HSA-2892247|reactome:R-HSA-3769402|reactome:R-HSA-452723|reactome:R-HSA-6785807|reactome:R-HSA-8986944 refseq:NP_001291692.1|refseq:NP_065883.1|refseq:NP_001291693.1|refseq:XP_011508114.1|refseq:XP_011508115.1|ensembl:ENSG00000143373(gene)|ensembl:ENST00000324048(transcript)|ensembl:ENST00000336715(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0046872"(metal ion binding)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR036236|interpro:IPR041697|mint:Q8N1G0 go:"GO:0005634"(nucleus) - - figure legend:ST3 F2C|comment:proteins that were enriched in the induced sample more than 6-fold|dataset:Brain Disease - Neurological Diseases & Disorders|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-daoy)|taxid:9606(Homo sapiens DAOY cerebellar medulloblastoma cell line) - 2020/12/29 2020/12/29 rogid:cn8gYfKDpQc8J2ygnqny32sIyyU9606 rogid:NR6q/E7oFHWVxeOkmRTyG6HKTvQ9606 rigid:Cnhili6Os5i+9KsmWx3iqclZGC0 false tandem tag:n-n - - - psi-mi:"MI:0658"(multidimensional protein identification technology) psi-mi:"MI:0658"(multidimensional protein identification technology) uniprotkb:P48431 uniprotkb:P42285 intact:EBI-6124081|uniprotkb:Q14537|ensembl:ENSP00000323588 intact:EBI-347612|uniprotkb:Q2M386|uniprotkb:Q6MZZ8|uniprotkb:Q6P170|uniprotkb:Q8N5R0|uniprotkb:Q8TAG2|ensembl:ENSP00000230640 psi-mi:sox2_human(display_long)|uniprotkb:SOX2(gene name)|psi-mi:SOX2(display_short) psi-mi:mtrex_human(display_long)|uniprotkb:MTREX(gene name)|psi-mi:MTREX(display_short)|uniprotkb:DOB1(gene name synonym)|uniprotkb:KIAA0052(gene name synonym)|uniprotkb:MTR4(gene name synonym)|uniprotkb:SKIV2L2(gene name synonym)|uniprotkb:Superkiller viralicidic activity 2-like 2(gene name synonym)|uniprotkb:TRAMP-like complex helicase(gene name synonym)|uniprotkb:ATP-dependent RNA helicase DOB1(gene name synonym)|uniprotkb:ATP-dependent RNA helicase SKIV2L2(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Cox et al. (2012) pubmed:23667531|imex:IM-28599 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-26574478|imex:IM-28599-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_003097.1|dip:DIP-59913N|ensembl:ENSG00000181449(gene)|ensembl:ENST00000325404(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001649"(osteoblast differentiation)|go:"GO:0001654"(eye development)|go:"GO:0001714"(endodermal cell fate specification)|go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006325"(chromatin organization)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0009611"(response to wounding)|go:"GO:0009653"(anatomical structure morphogenesis)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0021781"(glial cell fate commitment)|go:"GO:0021983"(pituitary gland development)|go:"GO:0021984"(adenohypophysis development)|go:"GO:0022409"(positive regulation of cell-cell adhesion)|go:"GO:0030154"(cell differentiation)|go:"GO:0030900"(forebrain development)|go:"GO:0035019"(somatic stem cell population maintenance)|go:"GO:0035198"(miRNA binding)|go:"GO:0042246"(tissue regeneration)|go:"GO:0043281"(regulation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0043410"(positive regulation of MAPK cascade)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045165"(cell fate commitment)|go:"GO:0045597"(positive regulation of cell differentiation)|go:"GO:0045665"(negative regulation of neuron differentiation)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048839"(inner ear development)|go:"GO:0050680"(negative regulation of epithelial cell proliferation)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0070848"(response to growth factor)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:0097150"(neuronal stem cell population maintenance)|interpro:IPR009071(High mobility group box, HMG)|interpro:IPR022097|interpro:IPR032643|interpro:IPR036910|mint:P48431|rcsb pdb:1O4X|rcsb pdb:2LE4|rcsb pdb:6T7B|rcsb pdb:6T90|rcsb pdb:6WX7|rcsb pdb:6WX8|rcsb pdb:6WX9|rcsb pdb:6YOV|reactome:R-HSA-2892245|reactome:R-HSA-2892247|reactome:R-HSA-3769402|reactome:R-HSA-452723|reactome:R-HSA-6785807|reactome:R-HSA-8986944 refseq:NP_056175.3|ensembl:ENSG00000039123(gene)|ensembl:ENST00000230640(transcript)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0000460"(maturation of 5.8S rRNA)|go:"GO:0003723"(RNA binding)|go:"GO:0003724"(RNA helicase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0006364"(rRNA processing)|go:"GO:0006401"(RNA catabolic process)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0016076"(snRNA catabolic process)|go:"GO:0016607"(nuclear speck)|go:"GO:0031499"(TRAMP complex)|go:"GO:0071013"(catalytic step 2 spliceosome)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR011545(DNA/RNA helicase, DEAD/DEAH box type, N-terminal)|interpro:IPR012961(DSH, C-terminal)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR016438(RNA helicase, ATP-dependent, SK12/DOB1)|interpro:IPR025696|interpro:IPR027417|mint:P42285|rcsb pdb:6C90|rcsb pdb:6D6Q|rcsb pdb:6D6R|rcsb pdb:6IEG|rcsb pdb:6IEH|rcsb pdb:6RO1|reactome:R-HSA-6791226|reactome:R-HSA-72163 go:"GO:0005634"(nucleus) - - figure legend:ST3 F2C|comment:proteins that were enriched in the induced sample more than 6-fold|dataset:Brain Disease - Neurological Diseases & Disorders|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-daoy)|taxid:9606(Homo sapiens DAOY cerebellar medulloblastoma cell line) - 2020/12/29 2020/12/29 rogid:cn8gYfKDpQc8J2ygnqny32sIyyU9606 rogid:bQdFDddFhetSp+CJ1S7Q5cm+g0k9606 rigid:Cnhili6Os5i+9KsmWx3iqclZGC0 false tandem tag:n-n - - - psi-mi:"MI:0658"(multidimensional protein identification technology) psi-mi:"MI:0658"(multidimensional protein identification technology) uniprotkb:P48431 uniprotkb:P13010 intact:EBI-6124081|uniprotkb:Q14537|ensembl:ENSP00000323588 intact:EBI-357997|uniprotkb:A8K3X5|uniprotkb:Q0Z7V0|uniprotkb:Q53HH7|uniprotkb:Q7M4N0|uniprotkb:Q4VBQ5|uniprotkb:Q9UCQ0|uniprotkb:Q9UCQ1|ensembl:ENSP00000375977|ensembl:ENSP00000375978 psi-mi:sox2_human(display_long)|uniprotkb:SOX2(gene name)|psi-mi:SOX2(display_short) psi-mi:xrcc5_human(display_long)|uniprotkb:XRCC5(gene name)|psi-mi:XRCC5(display_short)|uniprotkb:G22P2(gene name synonym)|uniprotkb:ATP-dependent DNA helicase II 80 kDa subunit(gene name synonym)|uniprotkb:Lupus Ku autoantigen protein p86(gene name synonym)|uniprotkb:86 kDa subunit of Ku antigen(gene name synonym)|uniprotkb:Ku86(gene name synonym)|uniprotkb:Ku80(gene name synonym)|uniprotkb:Thyroid-lupus autoantigen(gene name synonym)|uniprotkb:CTC box-binding factor 85 kDa subunit(gene name synonym)|uniprotkb:Nuclear factor IV(gene name synonym)|uniprotkb:DNA repair protein XRCC5(gene name synonym)|uniprotkb:"X-ray repair complementing defective repair in Chinese hamster cells 5 (double-strand-break rejoining)"(gene name synonym)|uniprotkb:ATP-dependent DNA helicase 2 subunit 2(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Cox et al. (2012) pubmed:23667531|imex:IM-28599 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-26574478|imex:IM-28599-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_003097.1|dip:DIP-59913N|ensembl:ENSG00000181449(gene)|ensembl:ENST00000325404(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001649"(osteoblast differentiation)|go:"GO:0001654"(eye development)|go:"GO:0001714"(endodermal cell fate specification)|go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006325"(chromatin organization)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0009611"(response to wounding)|go:"GO:0009653"(anatomical structure morphogenesis)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0021781"(glial cell fate commitment)|go:"GO:0021983"(pituitary gland development)|go:"GO:0021984"(adenohypophysis development)|go:"GO:0022409"(positive regulation of cell-cell adhesion)|go:"GO:0030154"(cell differentiation)|go:"GO:0030900"(forebrain development)|go:"GO:0035019"(somatic stem cell population maintenance)|go:"GO:0035198"(miRNA binding)|go:"GO:0042246"(tissue regeneration)|go:"GO:0043281"(regulation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0043410"(positive regulation of MAPK cascade)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045165"(cell fate commitment)|go:"GO:0045597"(positive regulation of cell differentiation)|go:"GO:0045665"(negative regulation of neuron differentiation)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048839"(inner ear development)|go:"GO:0050680"(negative regulation of epithelial cell proliferation)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0070848"(response to growth factor)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:0097150"(neuronal stem cell population maintenance)|interpro:IPR009071(High mobility group box, HMG)|interpro:IPR022097|interpro:IPR032643|interpro:IPR036910|mint:P48431|rcsb pdb:1O4X|rcsb pdb:2LE4|rcsb pdb:6T7B|rcsb pdb:6T90|rcsb pdb:6WX7|rcsb pdb:6WX8|rcsb pdb:6WX9|rcsb pdb:6YOV|reactome:R-HSA-2892245|reactome:R-HSA-2892247|reactome:R-HSA-3769402|reactome:R-HSA-452723|reactome:R-HSA-6785807|reactome:R-HSA-8986944 refseq:NP_066964.1|ensembl:ENST00000392132(transcript)|ensembl:ENSG00000079246(gene)|dip:DIP-31379N|go:"GO:0043085"(positive regulation of catalytic activity)|go:"GO:0043564"("Ku70:Ku80 complex")|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045027"(DNA end binding)|go:"GO:0045087"(innate immune response)|go:"GO:0045860"(positive regulation of protein kinase activity)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0048660"(regulation of smooth muscle cell proliferation)|go:"GO:0050769"(positive regulation of neurogenesis)|go:"GO:0051973"(positive regulation of telomerase activity)|go:"GO:0060218"(hematopoietic stem cell differentiation)|go:"GO:0070198"(protein localization to chromosome, telomeric region)|go:"GO:0070419"(nonhomologous end joining complex)|go:"GO:0071398"(cellular response to fatty acid)|go:"GO:0071475"(cellular hyperosmotic salinity response)|go:"GO:0071480"(cellular response to gamma radiation)|go:"GO:0071481"(cellular response to X-ray)|go:"GO:0090734"(site of DNA damage)|go:"GO:0008094"(ATP-dependent activity, acting on DNA)|go:"GO:0008283"(cell population proliferation)|go:"GO:0016020"(membrane)|go:"GO:0016787"(hydrolase activity)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032040"(small-subunit processome)|go:"GO:0032204"(regulation of telomere maintenance)|go:"GO:0032212"(positive regulation of telomere maintenance via telomerase)|go:"GO:0032991"(protein-containing complex)|go:"GO:0032993"(protein-DNA complex)|go:"GO:0034462"(small-subunit processome assembly)|go:"GO:0034511"(U3 snoRNA binding)|go:"GO:0034774"(secretory granule lumen)|go:"GO:0042162"(telomeric DNA binding)|go:"GO:0042493"|ensembl:ENST00000392133(transcript)|go:"GO:0000723"(telomere maintenance)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0000783"(nuclear telomere cap complex)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0002218"(activation of innate immune response)|go:"GO:0003677"(DNA binding)|go:"GO:0003678"(DNA helicase activity)|go:"GO:0003684"(damaged DNA binding)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006302"(double-strand break repair)|go:"GO:0006303"(double-strand break repair via nonhomologous end joining)|go:"GO:0006310"(DNA recombination)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0007420"(brain development)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008047"(enzyme activator activity)|go:"GO:1904430"(negative regulation of t-circle formation)|go:"GO:1990830"(cellular response to leukemia inhibitory factor)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR002035(von Willebrand factor, type A)|interpro:IPR005160(Ku70/Ku80 C-terminal arm)|interpro:IPR005161(Ku70/Ku80, N-terminal alpha/beta)|interpro:IPR006164(DNA helicase, ATP-dependent, Ku type)|interpro:IPR014893(Ku, C-terminal)|interpro:IPR016194(Spen Paralogue and Orthologue C-terminal-like)|interpro:IPR024193|interpro:IPR036465|interpro:IPR036494|mint:P13010|rcsb pdb:1JEQ|rcsb pdb:1JEY|rcsb pdb:1Q2Z|rcsb pdb:1RW2|rcsb pdb:3RZ9|rcsb pdb:5Y3R|rcsb pdb:6ERF|rcsb pdb:6ERG|rcsb pdb:6ERH|rcsb pdb:6ZH6|rcsb pdb:6ZHA|rcsb pdb:6ZHE|rcsb pdb:7AXZ|rcsb pdb:7K0Y|rcsb pdb:7K17|rcsb pdb:7K1J|rcsb pdb:7K1K|rcsb pdb:7K1N|rcsb pdb:7LSY|rcsb pdb:7LT3|reactome:R-HSA-164843|reactome:R-HSA-1834949|reactome:R-HSA-3270619|reactome:R-HSA-5693571|reactome:R-HSA-6798695 go:"GO:0005634"(nucleus) - - figure legend:ST3 F2C|comment:proteins that were enriched in the induced sample more than 6-fold|dataset:Brain Disease - Neurological Diseases & Disorders|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-daoy)|taxid:9606(Homo sapiens DAOY cerebellar medulloblastoma cell line) - 2020/12/29 2020/12/29 rogid:cn8gYfKDpQc8J2ygnqny32sIyyU9606 rogid:ZPJCWdA2YqOqXgfSRfDQCoEsyoA9606 rigid:Cnhili6Os5i+9KsmWx3iqclZGC0 false tandem tag:n-n - - - psi-mi:"MI:0658"(multidimensional protein identification technology) psi-mi:"MI:0658"(multidimensional protein identification technology) uniprotkb:P48431 uniprotkb:P04792 intact:EBI-6124081|uniprotkb:Q14537|ensembl:ENSP00000323588 intact:EBI-352682|uniprotkb:Q6FI47|uniprotkb:Q96C20|uniprotkb:Q96EI7|uniprotkb:Q9UC34|uniprotkb:Q9UC35|uniprotkb:Q9UC36|uniprotkb:Q9UC31|ensembl:ENSP00000248553|uniprotkb:B2R4N8 psi-mi:sox2_human(display_long)|uniprotkb:SOX2(gene name)|psi-mi:SOX2(display_short) psi-mi:hspb1_human(display_long)|uniprotkb:HSPB1(gene name)|psi-mi:HSPB1(display_short)|uniprotkb:HSP27(gene name synonym)|uniprotkb:HSP28(gene name synonym)|uniprotkb:Heat shock 27 kDa protein(gene name synonym)|uniprotkb:Stress-responsive protein 27(gene name synonym)|uniprotkb:Estrogen-regulated 24 kDa protein(gene name synonym)|uniprotkb:28 kDa heat shock protein(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Cox et al. (2012) pubmed:23667531|imex:IM-28599 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-26574478|imex:IM-28599-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_003097.1|dip:DIP-59913N|ensembl:ENSG00000181449(gene)|ensembl:ENST00000325404(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001649"(osteoblast differentiation)|go:"GO:0001654"(eye development)|go:"GO:0001714"(endodermal cell fate specification)|go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006325"(chromatin organization)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0009611"(response to wounding)|go:"GO:0009653"(anatomical structure morphogenesis)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0021781"(glial cell fate commitment)|go:"GO:0021983"(pituitary gland development)|go:"GO:0021984"(adenohypophysis development)|go:"GO:0022409"(positive regulation of cell-cell adhesion)|go:"GO:0030154"(cell differentiation)|go:"GO:0030900"(forebrain development)|go:"GO:0035019"(somatic stem cell population maintenance)|go:"GO:0035198"(miRNA binding)|go:"GO:0042246"(tissue regeneration)|go:"GO:0043281"(regulation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0043410"(positive regulation of MAPK cascade)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045165"(cell fate commitment)|go:"GO:0045597"(positive regulation of cell differentiation)|go:"GO:0045665"(negative regulation of neuron differentiation)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048839"(inner ear development)|go:"GO:0050680"(negative regulation of epithelial cell proliferation)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0070848"(response to growth factor)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:0097150"(neuronal stem cell population maintenance)|interpro:IPR009071(High mobility group box, HMG)|interpro:IPR022097|interpro:IPR032643|interpro:IPR036910|mint:P48431|rcsb pdb:1O4X|rcsb pdb:2LE4|rcsb pdb:6T7B|rcsb pdb:6T90|rcsb pdb:6WX7|rcsb pdb:6WX8|rcsb pdb:6WX9|rcsb pdb:6YOV|reactome:R-HSA-2892245|reactome:R-HSA-2892247|reactome:R-HSA-3769402|reactome:R-HSA-452723|reactome:R-HSA-6785807|reactome:R-HSA-8986944 refseq:NP_001531.1|ensembl:ENSG00000106211(gene)|ensembl:ENST00000248553(transcript)|go:"GO:0000502"(proteasome complex)|go:"GO:0001895"(retina homeostasis)|go:"GO:0001932"(regulation of protein phosphorylation)|go:"GO:0003723"(RNA binding)|go:"GO:0005080"(protein kinase C binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005819"(spindle)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005886"(plasma membrane)|go:"GO:0005925"(focal adhesion)|go:"GO:0006446"(regulation of translational initiation)|go:"GO:0006469"(negative regulation of protein kinase activity)|go:"GO:0006986"(response to unfolded protein)|go:"GO:0008426"(protein kinase C inhibitor activity)|go:"GO:0009615"(response to virus)|go:"GO:0010506"(regulation of autophagy)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030018"(Z disc)|go:"GO:0032731"(positive regulation of interleukin-1 beta production)|go:"GO:0032760"(positive regulation of tumor necrosis factor production)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0035924"(cellular response to vascular endothelial growth factor stimulus)|go:"GO:0038033"(positive regulation of endothelial cell chemotaxis by VEGF-activated vascular endothelial growth factor receptor signaling pathway)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043122"(regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043130"(ubiquitin binding)|go:"GO:0043536"(positive regulation of blood vessel endothelial cell migration)|go:"GO:0044183"(protein folding chaperone)|go:"GO:0045766"(positive regulation of angiogenesis)|go:"GO:0061077"(chaperone-mediated protein folding)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070527"(platelet aggregation)|go:"GO:0099641"(anterograde axonal protein transport)|go:"GO:1902176"(negative regulation of oxidative stress-induced intrinsic apoptotic signaling pathway)|go:"GO:1904115"(axon cytoplasm)|go:"GO:2001028"(positive regulation of endothelial cell chemotaxis)|interpro:IPR001436(Alpha crystallin/Heat shock protein)|interpro:IPR002068(Heat shock protein Hsp20)|interpro:IPR008978(HSP20-like chaperone)|interpro:IPR037876|mint:P04792|rcsb pdb:2N3J|rcsb pdb:3Q9P|rcsb pdb:3Q9Q|rcsb pdb:4MJH|rcsb pdb:6DV5|rcsb pdb:6GJH|reactome:R-HSA-4420097|reactome:R-HSA-450408|reactome:R-HSA-5687128|reactome:R-HSA-9009391|dip:DIP-412N go:"GO:0005634"(nucleus) - crc64:1B4DC44A6F6606D5 figure legend:ST3 F2C|comment:proteins that were enriched in the induced sample more than 6-fold|dataset:Brain Disease - Neurological Diseases & Disorders|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-daoy)|taxid:9606(Homo sapiens DAOY cerebellar medulloblastoma cell line) - 2020/12/29 2020/12/29 rogid:cn8gYfKDpQc8J2ygnqny32sIyyU9606 rogid:vrDXIdzP30aHSDLHOh2D4x54eJY9606 rigid:Cnhili6Os5i+9KsmWx3iqclZGC0 false tandem tag:n-n - - - psi-mi:"MI:0658"(multidimensional protein identification technology) psi-mi:"MI:0658"(multidimensional protein identification technology) uniprotkb:P48431 uniprotkb:Q8N7H5 intact:EBI-6124081|uniprotkb:Q14537|ensembl:ENSP00000323588 intact:EBI-2607770|uniprotkb:O75239|uniprotkb:Q9H166|uniprotkb:Q9NUU9|ensembl:ENSP00000221265|uniprotkb:M0QX35 psi-mi:sox2_human(display_long)|uniprotkb:SOX2(gene name)|psi-mi:SOX2(display_short) psi-mi:paf1_human(display_long)|uniprotkb:PAF1(gene name)|psi-mi:PAF1(display_short)|uniprotkb:PD2(gene name synonym)|uniprotkb:Pancreatic differentiation protein 2(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Cox et al. (2012) pubmed:23667531|imex:IM-28599 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-26574478|imex:IM-28599-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_003097.1|dip:DIP-59913N|ensembl:ENSG00000181449(gene)|ensembl:ENST00000325404(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001649"(osteoblast differentiation)|go:"GO:0001654"(eye development)|go:"GO:0001714"(endodermal cell fate specification)|go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006325"(chromatin organization)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0009611"(response to wounding)|go:"GO:0009653"(anatomical structure morphogenesis)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0021781"(glial cell fate commitment)|go:"GO:0021983"(pituitary gland development)|go:"GO:0021984"(adenohypophysis development)|go:"GO:0022409"(positive regulation of cell-cell adhesion)|go:"GO:0030154"(cell differentiation)|go:"GO:0030900"(forebrain development)|go:"GO:0035019"(somatic stem cell population maintenance)|go:"GO:0035198"(miRNA binding)|go:"GO:0042246"(tissue regeneration)|go:"GO:0043281"(regulation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0043410"(positive regulation of MAPK cascade)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045165"(cell fate commitment)|go:"GO:0045597"(positive regulation of cell differentiation)|go:"GO:0045665"(negative regulation of neuron differentiation)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048839"(inner ear development)|go:"GO:0050680"(negative regulation of epithelial cell proliferation)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0070848"(response to growth factor)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:0097150"(neuronal stem cell population maintenance)|interpro:IPR009071(High mobility group box, HMG)|interpro:IPR022097|interpro:IPR032643|interpro:IPR036910|mint:P48431|rcsb pdb:1O4X|rcsb pdb:2LE4|rcsb pdb:6T7B|rcsb pdb:6T90|rcsb pdb:6WX7|rcsb pdb:6WX8|rcsb pdb:6WX9|rcsb pdb:6YOV|reactome:R-HSA-2892245|reactome:R-HSA-2892247|reactome:R-HSA-3769402|reactome:R-HSA-452723|reactome:R-HSA-6785807|reactome:R-HSA-8986944 refseq:NP_061961.2|ensembl:ENSG00000006712(gene)|ensembl:ENST00000221265(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000993"(RNA polymerase II complex binding)|go:"GO:0001711"(endodermal cell fate commitment)|go:"GO:0003682"(chromatin binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006368"(transcription elongation from RNA polymerase II promoter)|go:"GO:0006378"(mRNA polyadenylation)|go:"GO:0010390"(histone monoubiquitination)|go:"GO:0016020"(membrane)|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0016584"(nucleosome positioning)|go:"GO:0016593"(Cdc73/Paf1 complex)|go:"GO:0019827"(stem cell population maintenance)|go:"GO:0030054"(cell junction)|go:"GO:0031062"(positive regulation of histone methylation)|go:"GO:0031442"(positive regulation of mRNA 3'-end processing)|go:"GO:0033523"(histone H2B ubiquitination)|go:"GO:0034504"(protein localization to nucleus)|go:"GO:0035327"|go:"GO:0045638"(negative regulation of myeloid cell differentiation)|go:"GO:0071222"(cellular response to lipopolysaccharide)|go:"GO:1902808"(positive regulation of cell cycle G1/S phase transition)|interpro:IPR007133(RNA polymerase II-associated, Paf1)|mint:Q8N7H5|rcsb pdb:4M6T|rcsb pdb:5ZYQ|rcsb pdb:6GMH|rcsb pdb:6TED|reactome:R-HSA-112382|reactome:R-HSA-674695|reactome:R-HSA-75955|reactome:R-HSA-8866654|refseq:NP_001243755.1|dip:DIP-48673N go:"GO:0005634"(nucleus) - - figure legend:ST3 F2C|comment:proteins that were enriched in the induced sample more than 6-fold|dataset:Brain Disease - Neurological Diseases & Disorders|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-daoy)|taxid:9606(Homo sapiens DAOY cerebellar medulloblastoma cell line) - 2020/12/29 2020/12/29 rogid:cn8gYfKDpQc8J2ygnqny32sIyyU9606 rogid:5Bf9gSdxgaufI30DVL8QAyVLqNk9606 rigid:Cnhili6Os5i+9KsmWx3iqclZGC0 false tandem tag:n-n - - - psi-mi:"MI:0658"(multidimensional protein identification technology) psi-mi:"MI:0658"(multidimensional protein identification technology) uniprotkb:P48431 uniprotkb:Q5C9Z4 intact:EBI-6124081|uniprotkb:Q14537|ensembl:ENSP00000323588 intact:EBI-2685618|uniprotkb:Q96I08|ensembl:ENSP00000275820 psi-mi:sox2_human(display_long)|uniprotkb:SOX2(gene name)|psi-mi:SOX2(display_short) psi-mi:nom1_human(display_long)|uniprotkb:C7orf3(gene name synonym)|uniprotkb:SGD1 homolog(gene name synonym)|uniprotkb:NOM1(gene name)|psi-mi:NOM1(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Cox et al. (2012) pubmed:23667531|imex:IM-28599 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-26574478|imex:IM-28599-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_003097.1|dip:DIP-59913N|ensembl:ENSG00000181449(gene)|ensembl:ENST00000325404(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001649"(osteoblast differentiation)|go:"GO:0001654"(eye development)|go:"GO:0001714"(endodermal cell fate specification)|go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006325"(chromatin organization)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0009611"(response to wounding)|go:"GO:0009653"(anatomical structure morphogenesis)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0021781"(glial cell fate commitment)|go:"GO:0021983"(pituitary gland development)|go:"GO:0021984"(adenohypophysis development)|go:"GO:0022409"(positive regulation of cell-cell adhesion)|go:"GO:0030154"(cell differentiation)|go:"GO:0030900"(forebrain development)|go:"GO:0035019"(somatic stem cell population maintenance)|go:"GO:0035198"(miRNA binding)|go:"GO:0042246"(tissue regeneration)|go:"GO:0043281"(regulation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0043410"(positive regulation of MAPK cascade)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045165"(cell fate commitment)|go:"GO:0045597"(positive regulation of cell differentiation)|go:"GO:0045665"(negative regulation of neuron differentiation)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048839"(inner ear development)|go:"GO:0050680"(negative regulation of epithelial cell proliferation)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0070848"(response to growth factor)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:0097150"(neuronal stem cell population maintenance)|interpro:IPR009071(High mobility group box, HMG)|interpro:IPR022097|interpro:IPR032643|interpro:IPR036910|mint:P48431|rcsb pdb:1O4X|rcsb pdb:2LE4|rcsb pdb:6T7B|rcsb pdb:6T90|rcsb pdb:6WX7|rcsb pdb:6WX8|rcsb pdb:6WX9|rcsb pdb:6YOV|reactome:R-HSA-2892245|reactome:R-HSA-2892247|reactome:R-HSA-3769402|reactome:R-HSA-452723|reactome:R-HSA-6785807|reactome:R-HSA-8986944 refseq:NP_612409.1|ensembl:ENSG00000146909(gene)|ensembl:ENST00000275820(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0005730"(nucleolus)|go:"GO:0042274"(ribosomal small subunit biogenesis)|go:"GO:0048820"(hair follicle maturation)|interpro:IPR003890(MIF4G-like, type 3)|interpro:IPR003891(Initiation factor eIF-4 gamma, MA3)|interpro:IPR016021(MIF4-like, type 1/2/3)|interpro:IPR016024(Armadillo-type fold)|mint:Q5C9Z4 go:"GO:0005634"(nucleus) - - figure legend:ST3 F2C|comment:proteins that were enriched in the induced sample more than 6-fold|dataset:Brain Disease - Neurological Diseases & Disorders|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-daoy)|taxid:9606(Homo sapiens DAOY cerebellar medulloblastoma cell line) - 2020/12/29 2020/12/29 rogid:cn8gYfKDpQc8J2ygnqny32sIyyU9606 rogid:1LScd95yytIZJ1/UFg9WTUiCmqg9606 rigid:Cnhili6Os5i+9KsmWx3iqclZGC0 false tandem tag:n-n - - - psi-mi:"MI:0658"(multidimensional protein identification technology) psi-mi:"MI:0658"(multidimensional protein identification technology) uniprotkb:P48431 uniprotkb:P39880 intact:EBI-6124081|uniprotkb:Q14537|ensembl:ENSP00000323588 intact:EBI-719064|uniprotkb:Q75LE5|uniprotkb:Q75MT2|uniprotkb:Q75MT3|uniprotkb:Q86UJ7|uniprotkb:Q6NYH4|uniprotkb:Q9UEV5|uniprotkb:B3KV79|uniprotkb:J3KQV9|intact:EBI-28989061|ensembl:ENSP00000292535|ensembl:ENSP00000450125 psi-mi:sox2_human(display_long)|uniprotkb:SOX2(gene name)|psi-mi:SOX2(display_short) psi-mi:cux1_human(display_long)|uniprotkb:CUTL1(gene name synonym)|uniprotkb:CCAAT displacement protein(gene name synonym)|uniprotkb:CUX1(gene name)|psi-mi:CUX1(display_short)|uniprotkb:Homeobox protein cux-1(gene name synonym)|uniprotkb:CDP/Cux p200(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Cox et al. (2012) pubmed:23667531|imex:IM-28599 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-26574478|imex:IM-28599-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_003097.1|dip:DIP-59913N|ensembl:ENSG00000181449(gene)|ensembl:ENST00000325404(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001649"(osteoblast differentiation)|go:"GO:0001654"(eye development)|go:"GO:0001714"(endodermal cell fate specification)|go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006325"(chromatin organization)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0009611"(response to wounding)|go:"GO:0009653"(anatomical structure morphogenesis)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0021781"(glial cell fate commitment)|go:"GO:0021983"(pituitary gland development)|go:"GO:0021984"(adenohypophysis development)|go:"GO:0022409"(positive regulation of cell-cell adhesion)|go:"GO:0030154"(cell differentiation)|go:"GO:0030900"(forebrain development)|go:"GO:0035019"(somatic stem cell population maintenance)|go:"GO:0035198"(miRNA binding)|go:"GO:0042246"(tissue regeneration)|go:"GO:0043281"(regulation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0043410"(positive regulation of MAPK cascade)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045165"(cell fate commitment)|go:"GO:0045597"(positive regulation of cell differentiation)|go:"GO:0045665"(negative regulation of neuron differentiation)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048839"(inner ear development)|go:"GO:0050680"(negative regulation of epithelial cell proliferation)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0070848"(response to growth factor)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:0097150"(neuronal stem cell population maintenance)|interpro:IPR009071(High mobility group box, HMG)|interpro:IPR022097|interpro:IPR032643|interpro:IPR036910|mint:P48431|rcsb pdb:1O4X|rcsb pdb:2LE4|rcsb pdb:6T7B|rcsb pdb:6T90|rcsb pdb:6WX7|rcsb pdb:6WX8|rcsb pdb:6WX9|rcsb pdb:6YOV|reactome:R-HSA-2892245|reactome:R-HSA-2892247|reactome:R-HSA-3769402|reactome:R-HSA-452723|reactome:R-HSA-6785807|reactome:R-HSA-8986944 refseq:NP_001189472.1|refseq:NP_853530.2|refseq:NP_001189474.1|ensembl:ENSP00000292535|ensembl:ENST00000360264|ensembl:ENSP00000353401|ensembl:ENST00000425244|ensembl:ENSP00000409745|ensembl:ENSP00000450125|ensembl:ENST00000549414|ensembl:ENSP00000446630|ensembl:ENST00000550008|ensembl:ENSP00000447373|ensembl:ENST00000556210|ensembl:ENSP00000451558|refseq:NP_001189473.1|refseq:NP_852477.1|ensembl:ENSG00000257923(gene)|ensembl:ENST00000292535(transcript)|ensembl:ENST00000546411(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000139"(Golgi membrane)|go:"GO:0000301"(retrograde transport, vesicle recycling within Golgi)|go:"GO:0000785"(chromatin)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007275"(multicellular organism development)|go:"GO:0030674"(protein-macromolecule adaptor activity)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0050775"(positive regulation of dendrite morphogenesis)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR001356(Homeobox)|interpro:IPR003350(Homeodomain protein CUT)|interpro:IPR009057(Homeodomain-like)|interpro:IPR010982(Lambda repressor-like, DNA-binding)|interpro:IPR017970|mint:P39880|reactome:R-HSA-1839117|reactome:R-HSA-5655302|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific) go:"GO:0005634"(nucleus) - - figure legend:ST3 F2C|comment:proteins that were enriched in the induced sample more than 6-fold|dataset:Brain Disease - Neurological Diseases & Disorders|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-daoy)|taxid:9606(Homo sapiens DAOY cerebellar medulloblastoma cell line) - 2020/12/29 2020/12/29 rogid:cn8gYfKDpQc8J2ygnqny32sIyyU9606 rogid:nzlzLWJ1xI4b6kEPnLVBKwbtwLs9606 rigid:Cnhili6Os5i+9KsmWx3iqclZGC0 false tandem tag:n-n - - - psi-mi:"MI:0658"(multidimensional protein identification technology) psi-mi:"MI:0658"(multidimensional protein identification technology) uniprotkb:P48431 uniprotkb:P61011 intact:EBI-6124081|uniprotkb:Q14537|ensembl:ENSP00000323588 intact:EBI-2854176|uniprotkb:B2R759|uniprotkb:P13624|uniprotkb:B4DUW6|ensembl:ENSP00000216774|ensembl:ENSP00000451818|ensembl:ENSP00000504518|ensembl:ENSP00000504673 psi-mi:sox2_human(display_long)|uniprotkb:SOX2(gene name)|psi-mi:SOX2(display_short) psi-mi:srp54_human(display_long)|uniprotkb:SRP54(gene name)|psi-mi:SRP54(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Cox et al. (2012) pubmed:23667531|imex:IM-28599 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-26574478|imex:IM-28599-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_003097.1|dip:DIP-59913N|ensembl:ENSG00000181449(gene)|ensembl:ENST00000325404(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001649"(osteoblast differentiation)|go:"GO:0001654"(eye development)|go:"GO:0001714"(endodermal cell fate specification)|go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006325"(chromatin organization)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0009611"(response to wounding)|go:"GO:0009653"(anatomical structure morphogenesis)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0021781"(glial cell fate commitment)|go:"GO:0021983"(pituitary gland development)|go:"GO:0021984"(adenohypophysis development)|go:"GO:0022409"(positive regulation of cell-cell adhesion)|go:"GO:0030154"(cell differentiation)|go:"GO:0030900"(forebrain development)|go:"GO:0035019"(somatic stem cell population maintenance)|go:"GO:0035198"(miRNA binding)|go:"GO:0042246"(tissue regeneration)|go:"GO:0043281"(regulation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0043410"(positive regulation of MAPK cascade)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045165"(cell fate commitment)|go:"GO:0045597"(positive regulation of cell differentiation)|go:"GO:0045665"(negative regulation of neuron differentiation)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048839"(inner ear development)|go:"GO:0050680"(negative regulation of epithelial cell proliferation)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0070848"(response to growth factor)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:0097150"(neuronal stem cell population maintenance)|interpro:IPR009071(High mobility group box, HMG)|interpro:IPR022097|interpro:IPR032643|interpro:IPR036910|mint:P48431|rcsb pdb:1O4X|rcsb pdb:2LE4|rcsb pdb:6T7B|rcsb pdb:6T90|rcsb pdb:6WX7|rcsb pdb:6WX8|rcsb pdb:6WX9|rcsb pdb:6YOV|reactome:R-HSA-2892245|reactome:R-HSA-2892247|reactome:R-HSA-3769402|reactome:R-HSA-452723|reactome:R-HSA-6785807|reactome:R-HSA-8986944 refseq:XP_011535408.1|refseq:NP_001139754.1|refseq:NP_003127.1|ensembl:ENSG00000100883(gene)|ensembl:ENST00000678963(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005786"(signal recognition particle, endoplasmic reticulum targeting)|go:"GO:0005829"(cytosol)|go:"GO:0006614"(SRP-dependent cotranslational protein targeting to membrane)|go:"GO:0006616"(SRP-dependent cotranslational protein targeting to membrane, translocation)|go:"GO:0006617"(SRP-dependent cotranslational protein targeting to membrane, signal sequence recognition)|go:"GO:0008312"(7S RNA binding)|go:"GO:0016607"(nuclear speck)|go:"GO:0019003"(GDP binding)|go:"GO:0030593"(neutrophil chemotaxis)|go:"GO:0030851"(granulocyte differentiation)|go:"GO:0030942"(endoplasmic reticulum signal peptide binding)|go:"GO:0031017"(exocrine pancreas development)|go:"GO:0043021"(ribonucleoprotein complex binding)|go:"GO:0045047"(protein targeting to ER)|interpro:IPR000897(Signal recognition particle, SRP54 subunit, GTPase)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR004125(Signal recognition particle, SRP54 subunit, M-domain)|interpro:IPR006325(Signal recognition particle, SRP54 subunit)|interpro:IPR013822(Signal recognition particle, SRP54 subunit, helical bundle)|interpro:IPR022941|interpro:IPR027417|interpro:IPR036225|interpro:IPR036891|interpro:IPR042101|mint:P61011|rcsb pdb:1MFQ|rcsb pdb:1QB2|rcsb pdb:5L3Q|rcsb pdb:6Y2Z|rcsb pdb:6Y30|rcsb pdb:6Y31|rcsb pdb:6Y32|rcsb pdb:7NFX|ensembl:ENST00000216774(transcript)|reactome:R-HSA-1799339|ensembl:ENST00000556994(transcript)|ensembl:ENST00000677647(transcript) go:"GO:0005634"(nucleus) - - figure legend:ST3 F2C|comment:proteins that were enriched in the induced sample more than 6-fold|dataset:Brain Disease - Neurological Diseases & Disorders|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-daoy)|taxid:9606(Homo sapiens DAOY cerebellar medulloblastoma cell line) - 2020/12/29 2020/12/29 rogid:cn8gYfKDpQc8J2ygnqny32sIyyU9606 rogid:8iRlU+NvhLEJNv7B90TAZyRqwiY9606 rigid:Cnhili6Os5i+9KsmWx3iqclZGC0 false tandem tag:n-n - - - psi-mi:"MI:0658"(multidimensional protein identification technology) psi-mi:"MI:0658"(multidimensional protein identification technology) uniprotkb:P48431 uniprotkb:Q9BWF3 intact:EBI-6124081|uniprotkb:Q14537|ensembl:ENSP00000323588 intact:EBI-2856454|uniprotkb:B3KUN0|uniprotkb:Q8WU85|uniprotkb:Q6P1P2|uniprotkb:O02916|uniprotkb:Q4VC48|uniprotkb:B4E1U0|uniprotkb:E7EQS3|ensembl:ENSP00000309166|ensembl:ENSP00000386561|ensembl:ENSP00000386894 psi-mi:sox2_human(display_long)|uniprotkb:SOX2(gene name)|psi-mi:SOX2(display_short) psi-mi:rbm4_human(display_long)|uniprotkb:RBM4(gene name)|psi-mi:RBM4(display_short)|uniprotkb:RBM4A(gene name synonym)|uniprotkb:Lark homolog(gene name synonym)|uniprotkb:RNA-binding motif protein 4(gene name synonym)|uniprotkb:RNA-binding motif protein 4a(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Cox et al. (2012) pubmed:23667531|imex:IM-28599 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-26574478|imex:IM-28599-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_003097.1|dip:DIP-59913N|ensembl:ENSG00000181449(gene)|ensembl:ENST00000325404(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001649"(osteoblast differentiation)|go:"GO:0001654"(eye development)|go:"GO:0001714"(endodermal cell fate specification)|go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006325"(chromatin organization)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0009611"(response to wounding)|go:"GO:0009653"(anatomical structure morphogenesis)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0021781"(glial cell fate commitment)|go:"GO:0021983"(pituitary gland development)|go:"GO:0021984"(adenohypophysis development)|go:"GO:0022409"(positive regulation of cell-cell adhesion)|go:"GO:0030154"(cell differentiation)|go:"GO:0030900"(forebrain development)|go:"GO:0035019"(somatic stem cell population maintenance)|go:"GO:0035198"(miRNA binding)|go:"GO:0042246"(tissue regeneration)|go:"GO:0043281"(regulation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0043410"(positive regulation of MAPK cascade)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045165"(cell fate commitment)|go:"GO:0045597"(positive regulation of cell differentiation)|go:"GO:0045665"(negative regulation of neuron differentiation)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048839"(inner ear development)|go:"GO:0050680"(negative regulation of epithelial cell proliferation)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0070848"(response to growth factor)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:0097150"(neuronal stem cell population maintenance)|interpro:IPR009071(High mobility group box, HMG)|interpro:IPR022097|interpro:IPR032643|interpro:IPR036910|mint:P48431|rcsb pdb:1O4X|rcsb pdb:2LE4|rcsb pdb:6T7B|rcsb pdb:6T90|rcsb pdb:6WX7|rcsb pdb:6WX8|rcsb pdb:6WX9|rcsb pdb:6YOV|reactome:R-HSA-2892245|reactome:R-HSA-2892247|reactome:R-HSA-3769402|reactome:R-HSA-452723|reactome:R-HSA-6785807|reactome:R-HSA-8986944 refseq:NP_001185772.1|refseq:NP_002887.2|refseq:NP_001185773.1|dip:DIP-44199N|ensembl:ENSG00000173933(gene)|ensembl:ENST00000310092(transcript)|ensembl:ENST00000408993(transcript)|ensembl:ENST00000409406(transcript)|go:"GO:0000381"(regulation of alternative mRNA splicing, via spliceosome)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0002190"(cap-independent translational initiation)|go:"GO:0002192"(IRES-dependent translational initiation of linear mRNA)|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0003730"(mRNA 3'-UTR binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006396"(RNA processing)|go:"GO:0008270"(zinc ion binding)|go:"GO:0010494"(cytoplasmic stress granule)|go:"GO:0016607"(nuclear speck)|go:"GO:0017148"(negative regulation of translation)|go:"GO:0030154"(cell differentiation)|go:"GO:0030332"(cyclin binding)|go:"GO:0032055"(negative regulation of translation in response to stress)|go:"GO:0035198"(miRNA binding)|go:"GO:0035278"(miRNA-mediated gene silencing by inhibition of translation)|go:"GO:0043153"(entrainment of circadian clock by photoperiod)|go:"GO:0045947"(negative regulation of translational initiation)|go:"GO:0046685"(response to arsenic-containing substance)|go:"GO:0046822"(regulation of nucleocytoplasmic transport)|go:"GO:0051149"(positive regulation of muscle cell differentiation)|go:"GO:0097157"(pre-mRNA intronic binding)|go:"GO:0097158"(pre-mRNA intronic pyrimidine-rich binding)|go:"GO:0097167"(circadian regulation of translation)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR001878(Zinc finger, CCHC-type)|interpro:IPR034897|interpro:IPR034898|interpro:IPR035979|mint:Q9BWF3|rcsb pdb:2DNQ|reactome:R-HSA-400253|interpro:IPR012677(Nucleotide-binding, alpha-beta plait) go:"GO:0005634"(nucleus) - - figure legend:ST3 F2C|comment:proteins that were enriched in the induced sample more than 6-fold|dataset:Brain Disease - Neurological Diseases & Disorders|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-daoy)|taxid:9606(Homo sapiens DAOY cerebellar medulloblastoma cell line) - 2020/12/29 2020/12/29 rogid:cn8gYfKDpQc8J2ygnqny32sIyyU9606 rogid:hbW6dv/AEWQz3mWvA2/9n8h/bbA9606 rigid:Cnhili6Os5i+9KsmWx3iqclZGC0 false tandem tag:n-n - - - psi-mi:"MI:0658"(multidimensional protein identification technology) psi-mi:"MI:0658"(multidimensional protein identification technology) uniprotkb:P48431 uniprotkb:Q13509 intact:EBI-6124081|uniprotkb:Q14537|ensembl:ENSP00000323588 intact:EBI-350989|uniprotkb:Q9BTZ0|uniprotkb:Q9BW10|ensembl:ENSP00000320295|uniprotkb:A8K854 psi-mi:sox2_human(display_long)|uniprotkb:SOX2(gene name)|psi-mi:SOX2(display_short) psi-mi:tbb3_human(display_long)|uniprotkb:TUBB3(gene name)|psi-mi:TUBB3(display_short)|uniprotkb:TUBB4(gene name synonym)|uniprotkb:Tubulin beta-III(gene name synonym)|uniprotkb:Tubulin beta-4 chain(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Cox et al. (2012) pubmed:23667531|imex:IM-28599 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-26574478|imex:IM-28599-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_003097.1|dip:DIP-59913N|ensembl:ENSG00000181449(gene)|ensembl:ENST00000325404(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001649"(osteoblast differentiation)|go:"GO:0001654"(eye development)|go:"GO:0001714"(endodermal cell fate specification)|go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006325"(chromatin organization)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0009611"(response to wounding)|go:"GO:0009653"(anatomical structure morphogenesis)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0021781"(glial cell fate commitment)|go:"GO:0021983"(pituitary gland development)|go:"GO:0021984"(adenohypophysis development)|go:"GO:0022409"(positive regulation of cell-cell adhesion)|go:"GO:0030154"(cell differentiation)|go:"GO:0030900"(forebrain development)|go:"GO:0035019"(somatic stem cell population maintenance)|go:"GO:0035198"(miRNA binding)|go:"GO:0042246"(tissue regeneration)|go:"GO:0043281"(regulation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0043410"(positive regulation of MAPK cascade)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045165"(cell fate commitment)|go:"GO:0045597"(positive regulation of cell differentiation)|go:"GO:0045665"(negative regulation of neuron differentiation)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048839"(inner ear development)|go:"GO:0050680"(negative regulation of epithelial cell proliferation)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0070848"(response to growth factor)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:0097150"(neuronal stem cell population maintenance)|interpro:IPR009071(High mobility group box, HMG)|interpro:IPR022097|interpro:IPR032643|interpro:IPR036910|mint:P48431|rcsb pdb:1O4X|rcsb pdb:2LE4|rcsb pdb:6T7B|rcsb pdb:6T90|rcsb pdb:6WX7|rcsb pdb:6WX8|rcsb pdb:6WX9|rcsb pdb:6YOV|reactome:R-HSA-2892245|reactome:R-HSA-2892247|reactome:R-HSA-3769402|reactome:R-HSA-452723|reactome:R-HSA-6785807|reactome:R-HSA-8986944 refseq:NP_001184110.1|refseq:NP_006077.2|reactome:R-HSA-6811434|reactome:R-HSA-6811436|reactome:R-HSA-68877|reactome:R-HSA-8852276|reactome:R-HSA-8955332|reactome:R-HSA-9609690|reactome:R-HSA-9609736|reactome:R-HSA-9619483|reactome:R-HSA-9646399|reactome:R-HSA-9648025|reactome:R-HSA-9668328|reactome:R-HSA-983189|reactome:R-HSA-6807878|ensembl:ENSG00000258947(gene)|ensembl:ENST00000315491(transcript)|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0005200"(structural constituent of cytoskeleton)|go:"GO:0005525"(GTP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005874"(microtubule)|go:"GO:0007411"(axon guidance)|go:"GO:0030027"(lamellipodium)|go:"GO:0030175"(filopodium)|go:"GO:0030424"(axon)|go:"GO:0030425"(dendrite)|go:"GO:0030426"(growth cone)|go:"GO:0042277"(peptide binding)|go:"GO:0043025"(neuronal cell body)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071944"(cell periphery)|go:"GO:1990791"(dorsal root ganglion development)|go:"GO:1990890"(netrin receptor binding)|interpro:IPR000217(Tubulin)|interpro:IPR002453(Beta tubulin)|interpro:IPR003008(Tubulin/FtsZ, GTPase)|interpro:IPR008280(Tubulin/FtsZ, C-terminal)|interpro:IPR013838(Beta tubulin, autoregulation binding site)|interpro:IPR017975|interpro:IPR018316|interpro:IPR023123|interpro:IPR036525|interpro:IPR037103|mint:Q13509|rcsb pdb:5IJ9|rcsb pdb:5JCO|rcsb pdb:6E7B|rcsb pdb:6S8L|rcsb pdb:6WSL|reactome:R-HSA-1445148|reactome:R-HSA-190840|reactome:R-HSA-190861|reactome:R-HSA-2132295|reactome:R-HSA-2467813|reactome:R-HSA-2500257|reactome:R-HSA-3371497|reactome:R-HSA-380320|reactome:R-HSA-389957|reactome:R-HSA-389960|reactome:R-HSA-389977|reactome:R-HSA-437239|reactome:R-HSA-5610787|reactome:R-HSA-5617833|reactome:R-HSA-5620924|reactome:R-HSA-5626467|reactome:R-HSA-5663220|rcsb pdb:5IJ0|dip:DIP-31505N go:"GO:0005634"(nucleus) - - figure legend:ST3 F2C|comment:proteins that were enriched in the induced sample more than 6-fold|dataset:Brain Disease - Neurological Diseases & Disorders|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-daoy)|taxid:9606(Homo sapiens DAOY cerebellar medulloblastoma cell line) - 2020/12/29 2020/12/29 rogid:cn8gYfKDpQc8J2ygnqny32sIyyU9606 rogid:A69G+idFQmuzkmCsGyBtGVqglSo9606 rigid:Cnhili6Os5i+9KsmWx3iqclZGC0 false tandem tag:n-n - - - psi-mi:"MI:0658"(multidimensional protein identification technology) psi-mi:"MI:0658"(multidimensional protein identification technology) uniprotkb:P48431 uniprotkb:Q9ULU4 intact:EBI-6124081|uniprotkb:Q14537|ensembl:ENSP00000323588 intact:EBI-765834|uniprotkb:Q13517|uniprotkb:Q4JJ94|uniprotkb:Q4JJ95|uniprotkb:Q5TH09|uniprotkb:Q6MZM1|uniprotkb:Q8WXC5|uniprotkb:Q9H1F3|uniprotkb:Q9H1F4|uniprotkb:Q9H1F5|uniprotkb:Q9H1L8|uniprotkb:Q9H1L9|uniprotkb:Q9H2G5|uniprotkb:Q9NYN3|uniprotkb:Q9UIX6|uniprotkb:Q2HXV7|uniprotkb:E1P5U5|uniprotkb:B7Z680|uniprotkb:Q2HXV2|uniprotkb:Q2HXV8|uniprotkb:Q2HXW0|uniprotkb:Q2HXW1|uniprotkb:Q2HXW2|uniprotkb:Q2HXV4|uniprotkb:Q2HXV9|uniprotkb:B3KVL2|uniprotkb:B7Z2A8|uniprotkb:B7Z3E0|uniprotkb:B7ZM62|uniprotkb:F5H0X3|uniprotkb:H7C0U2|uniprotkb:J3KPU3|uniprotkb:Q2HXV1|uniprotkb:Q2HXV3|uniprotkb:Q5TH11|ensembl:ENSP00000312237 psi-mi:sox2_human(display_long)|uniprotkb:SOX2(gene name)|psi-mi:SOX2(display_short) psi-mi:pkcb1_human(display_long)|uniprotkb:Rack7(gene name synonym)|uniprotkb:Cutaneous T-cell lymphoma-associated antigen se14-3(gene name synonym)|uniprotkb:Zinc finger MYND domain-containing protein 8(gene name synonym)|uniprotkb:ZMYND8(gene name)|psi-mi:ZMYND8(display_short)|uniprotkb:KIAA1125(gene name synonym)|uniprotkb:RACK7(gene name synonym)|uniprotkb:PRKCBP1(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Cox et al. (2012) pubmed:23667531|imex:IM-28599 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-26574478|imex:IM-28599-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_003097.1|dip:DIP-59913N|ensembl:ENSG00000181449(gene)|ensembl:ENST00000325404(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001649"(osteoblast differentiation)|go:"GO:0001654"(eye development)|go:"GO:0001714"(endodermal cell fate specification)|go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006325"(chromatin organization)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0009611"(response to wounding)|go:"GO:0009653"(anatomical structure morphogenesis)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0021781"(glial cell fate commitment)|go:"GO:0021983"(pituitary gland development)|go:"GO:0021984"(adenohypophysis development)|go:"GO:0022409"(positive regulation of cell-cell adhesion)|go:"GO:0030154"(cell differentiation)|go:"GO:0030900"(forebrain development)|go:"GO:0035019"(somatic stem cell population maintenance)|go:"GO:0035198"(miRNA binding)|go:"GO:0042246"(tissue regeneration)|go:"GO:0043281"(regulation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0043410"(positive regulation of MAPK cascade)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045165"(cell fate commitment)|go:"GO:0045597"(positive regulation of cell differentiation)|go:"GO:0045665"(negative regulation of neuron differentiation)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048839"(inner ear development)|go:"GO:0050680"(negative regulation of epithelial cell proliferation)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0070848"(response to growth factor)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:0097150"(neuronal stem cell population maintenance)|interpro:IPR009071(High mobility group box, HMG)|interpro:IPR022097|interpro:IPR032643|interpro:IPR036910|mint:P48431|rcsb pdb:1O4X|rcsb pdb:2LE4|rcsb pdb:6T7B|rcsb pdb:6T90|rcsb pdb:6WX7|rcsb pdb:6WX8|rcsb pdb:6WX9|rcsb pdb:6YOV|reactome:R-HSA-2892245|reactome:R-HSA-2892247|reactome:R-HSA-3769402|reactome:R-HSA-452723|reactome:R-HSA-6785807|reactome:R-HSA-8986944 refseq:NP_036540.3|refseq:NP_898868.1|refseq:NP_898869.1|refseq:XP_011527053.1|refseq:NP_001268711.1|refseq:NP_001268706.1|refseq:NP_001268710.1|ensembl:ENST00000262975|ensembl:ENSP00000262975|ensembl:ENSP00000312237|ensembl:ENST00000352431|ensembl:ENSP00000335537|ensembl:ENST00000355972|ensembl:ENSP00000348246|ensembl:ENST00000360911|ensembl:ENSP00000354166|ensembl:ENST00000372023|ensembl:ENSP00000361093|ensembl:ENST00000396281|ensembl:ENSP00000379577|refseq:NP_001268702.1|refseq:NP_001268703.1|refseq:NP_001268704.1|refseq:NP_001268705.1|refseq:NP_001268707.1|refseq:NP_001268712.1|refseq:XP_005260417.1|refseq:XP_005260423.1|ensembl:ENST00000446994|ensembl:ENSP00000396725|ensembl:ENST00000458360|ensembl:ENSP00000392964|ensembl:ENST00000461685|ensembl:ENSP00000418210|ensembl:ENST00000471951|ensembl:ENSP00000420095|ensembl:ENST00000536340|ensembl:ENSP00000439800|ensembl:ENST00000540497|ensembl:ENSP00000443086|refseq:NP_001268713.1|refseq:XP_005260413.1|refseq:NP_001268700.1|refseq:NP_001268701.1|refseq:XP_006723825.1|refseq:XP_016883250.1|refseq:XP_016883256.1|refseq:XP_016883257.1|go:"GO:0005737"(cytoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0008270"(zinc ion binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030336"(negative regulation of cell migration)|go:"GO:0035064"(methylated histone binding)|go:"GO:0043197"(dendritic spine)|go:"GO:0043198"(dendritic shaft)|go:"GO:0047485"(protein N-terminus binding)|go:"GO:0051491"(positive regulation of filopodium assembly)|go:"GO:0060999"(positive regulation of dendritic spine development)|go:"GO:0070577"(lysine-acetylated histone binding)|go:"GO:0098815"(modulation of excitatory postsynaptic potential)|go:"GO:0140297"(DNA-binding transcription factor binding)|go:"GO:1902897"(regulation of postsynaptic density protein 95 clustering)|go:"GO:1902952"(positive regulation of dendritic spine maintenance)|interpro:IPR000313(PWWP)|interpro:IPR001487(Bromodomain)|interpro:IPR001965(Zinc finger, PHD-type)|interpro:IPR002893(Zinc finger, MYND-type)|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR019786|interpro:IPR019787|interpro:IPR021931|interpro:IPR035505|interpro:IPR036427|interpro:IPR037967|interpro:IPR044075|mint:Q9ULU4|rcsb pdb:4COS|rcsb pdb:5B73|rcsb pdb:5MQ4|go:"GO:0005654"(nucleoplasm)|rcsb pdb:5Y1Z|ensembl:ENSG00000101040(gene)|ensembl:ENST00000311275(transcript)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005634"(nucleus) go:"GO:0005634"(nucleus) - - figure legend:ST3 F2C|comment:proteins that were enriched in the induced sample more than 6-fold|dataset:Brain Disease - Neurological Diseases & Disorders|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-daoy)|taxid:9606(Homo sapiens DAOY cerebellar medulloblastoma cell line) - 2020/12/29 2020/12/29 rogid:cn8gYfKDpQc8J2ygnqny32sIyyU9606 rogid:z46jFcDnmKauE75GMeApPZmfdDM9606 rigid:Cnhili6Os5i+9KsmWx3iqclZGC0 false tandem tag:n-n - - - psi-mi:"MI:0658"(multidimensional protein identification technology) psi-mi:"MI:0658"(multidimensional protein identification technology) uniprotkb:P48431 uniprotkb:O00267 intact:EBI-6124081|uniprotkb:Q14537|ensembl:ENSP00000323588 intact:EBI-710464|ensembl:ENSP00000404029|ensembl:ENSP00000469090|ensembl:ENSP00000470252|uniprotkb:O43279|uniprotkb:Q59G52|uniprotkb:Q99639 psi-mi:sox2_human(display_long)|uniprotkb:SOX2(gene name)|psi-mi:SOX2(display_short) psi-mi:spt5h_human(display_long)|uniprotkb:DRB sensitivity-inducing factor large subunit(gene name synonym)|uniprotkb:DRB sensitivity-inducing factor 160 kDa subunit(gene name synonym)|uniprotkb:Tat-cotransactivator 1 protein(gene name synonym)|uniprotkb:SUPT5H(gene name)|psi-mi:SUPT5H(display_short)|uniprotkb:SPT5(gene name synonym)|uniprotkb:SPT5H(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Cox et al. (2012) pubmed:23667531|imex:IM-28599 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-26574478|imex:IM-28599-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_003097.1|dip:DIP-59913N|ensembl:ENSG00000181449(gene)|ensembl:ENST00000325404(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001649"(osteoblast differentiation)|go:"GO:0001654"(eye development)|go:"GO:0001714"(endodermal cell fate specification)|go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006325"(chromatin organization)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0009611"(response to wounding)|go:"GO:0009653"(anatomical structure morphogenesis)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0021781"(glial cell fate commitment)|go:"GO:0021983"(pituitary gland development)|go:"GO:0021984"(adenohypophysis development)|go:"GO:0022409"(positive regulation of cell-cell adhesion)|go:"GO:0030154"(cell differentiation)|go:"GO:0030900"(forebrain development)|go:"GO:0035019"(somatic stem cell population maintenance)|go:"GO:0035198"(miRNA binding)|go:"GO:0042246"(tissue regeneration)|go:"GO:0043281"(regulation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0043410"(positive regulation of MAPK cascade)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045165"(cell fate commitment)|go:"GO:0045597"(positive regulation of cell differentiation)|go:"GO:0045665"(negative regulation of neuron differentiation)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048839"(inner ear development)|go:"GO:0050680"(negative regulation of epithelial cell proliferation)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0070848"(response to growth factor)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:0097150"(neuronal stem cell population maintenance)|interpro:IPR009071(High mobility group box, HMG)|interpro:IPR022097|interpro:IPR032643|interpro:IPR036910|mint:P48431|rcsb pdb:1O4X|rcsb pdb:2LE4|rcsb pdb:6T7B|rcsb pdb:6T90|rcsb pdb:6WX7|rcsb pdb:6WX8|rcsb pdb:6WX9|rcsb pdb:6YOV|reactome:R-HSA-2892245|reactome:R-HSA-2892247|reactome:R-HSA-3769402|reactome:R-HSA-452723|reactome:R-HSA-6785807|reactome:R-HSA-8986944 refseq:NP_001124296.1|refseq:NP_001124297.1|refseq:NP_003160.2|refseq:NP_001104490.1|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006368"(transcription elongation from RNA polymerase II promoter)|go:"GO:0016239"(positive regulation of macroautophagy)|go:"GO:0019899"(enzyme binding)|go:"GO:0032044"(DSIF complex)|go:"GO:0032785"(negative regulation of DNA-templated transcription, elongation)|go:"GO:0032786"(positive regulation of DNA-templated transcription, elongation)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046982"(protein heterodimerization activity)|ensembl:ENSG00000196235(gene)|ensembl:ENST00000432763(transcript)|ensembl:ENST00000598725(transcript)|ensembl:ENST00000599117(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0003682"(chromatin binding)|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:1900364"(negative regulation of mRNA polyadenylation)|interpro:IPR005100(Supt5 repeat)|interpro:IPR005824(KOW)|interpro:IPR006645(Transcription antitermination protein, NusG, N-terminal)|interpro:IPR008991(Translation protein SH3-like)|interpro:IPR014722(Translation protein SH3-like, subgroup)|interpro:IPR017071(Transcription elongation factor Spt5)|interpro:IPR022581|interpro:IPR024945|interpro:IPR036735|interpro:IPR039385|interpro:IPR039659|interpro:IPR041973|interpro:IPR041975|interpro:IPR041976|interpro:IPR041977|interpro:IPR041978|interpro:IPR041980|mint:O00267|rcsb pdb:2DO3|rcsb pdb:2E6Z|rcsb pdb:2E70|rcsb pdb:3H7H|rcsb pdb:4L1U|rcsb pdb:5OHO|rcsb pdb:5OHQ|rcsb pdb:5OIK|rcsb pdb:5U98|rcsb pdb:6EQY|rcsb pdb:6ER0|rcsb pdb:6GMH|rcsb pdb:6GML|rcsb pdb:6TED|reactome:R-HSA-112382|reactome:R-HSA-113418|reactome:R-HSA-167152|reactome:R-HSA-167158|reactome:R-HSA-167160|reactome:R-HSA-167200|reactome:R-HSA-167238|reactome:R-HSA-167242|reactome:R-HSA-167243|reactome:R-HSA-167246|reactome:R-HSA-167287|reactome:R-HSA-167290|reactome:R-HSA-674695|reactome:R-HSA-6796648|reactome:R-HSA-6807505|reactome:R-HSA-72086|reactome:R-HSA-75955|reactome:R-HSA-77075|refseq:NP_001306920.1|refseq:NP_001306919.1|dip:DIP-29014N go:"GO:0005634"(nucleus) - - figure legend:ST3 F2C|comment:proteins that were enriched in the induced sample more than 6-fold|dataset:Brain Disease - Neurological Diseases & Disorders|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-daoy)|taxid:9606(Homo sapiens DAOY cerebellar medulloblastoma cell line) - 2020/12/29 2020/12/29 rogid:cn8gYfKDpQc8J2ygnqny32sIyyU9606 rogid:8VodOhZyrmNy3xxDTTsB8KugN849606 rigid:Cnhili6Os5i+9KsmWx3iqclZGC0 false tandem tag:n-n - - - psi-mi:"MI:0658"(multidimensional protein identification technology) psi-mi:"MI:0658"(multidimensional protein identification technology) uniprotkb:P48431 uniprotkb:P31689 intact:EBI-6124081|uniprotkb:Q14537|ensembl:ENSP00000323588 intact:EBI-347834|ensembl:ENSP00000369127|uniprotkb:Q5T7Q0|uniprotkb:Q86TL9 psi-mi:sox2_human(display_long)|uniprotkb:SOX2(gene name)|psi-mi:SOX2(display_short) psi-mi:dnja1_human(display_long)|uniprotkb:DNAJA1(gene name)|psi-mi:DNAJA1(display_short)|uniprotkb:DNAJ2(gene name synonym)|uniprotkb:HDJ2(gene name synonym)|uniprotkb:HSJ2(gene name synonym)|uniprotkb:HSPF4(gene name synonym)|uniprotkb:Heat shock 40 kDa protein 4(gene name synonym)|uniprotkb:DnaJ protein homolog 2(gene name synonym)|uniprotkb:Human DnaJ protein 2(gene name synonym)|uniprotkb:Heat shock protein J2(gene name synonym)|uniprotkb:HSDJ(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Cox et al. (2012) pubmed:23667531|imex:IM-28599 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-26574478|imex:IM-28599-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_003097.1|dip:DIP-59913N|ensembl:ENSG00000181449(gene)|ensembl:ENST00000325404(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001649"(osteoblast differentiation)|go:"GO:0001654"(eye development)|go:"GO:0001714"(endodermal cell fate specification)|go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006325"(chromatin organization)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0009611"(response to wounding)|go:"GO:0009653"(anatomical structure morphogenesis)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0021781"(glial cell fate commitment)|go:"GO:0021983"(pituitary gland development)|go:"GO:0021984"(adenohypophysis development)|go:"GO:0022409"(positive regulation of cell-cell adhesion)|go:"GO:0030154"(cell differentiation)|go:"GO:0030900"(forebrain development)|go:"GO:0035019"(somatic stem cell population maintenance)|go:"GO:0035198"(miRNA binding)|go:"GO:0042246"(tissue regeneration)|go:"GO:0043281"(regulation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0043410"(positive regulation of MAPK cascade)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045165"(cell fate commitment)|go:"GO:0045597"(positive regulation of cell differentiation)|go:"GO:0045665"(negative regulation of neuron differentiation)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048839"(inner ear development)|go:"GO:0050680"(negative regulation of epithelial cell proliferation)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0070848"(response to growth factor)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:0097150"(neuronal stem cell population maintenance)|interpro:IPR009071(High mobility group box, HMG)|interpro:IPR022097|interpro:IPR032643|interpro:IPR036910|mint:P48431|rcsb pdb:1O4X|rcsb pdb:2LE4|rcsb pdb:6T7B|rcsb pdb:6T90|rcsb pdb:6WX7|rcsb pdb:6WX8|rcsb pdb:6WX9|rcsb pdb:6YOV|reactome:R-HSA-2892245|reactome:R-HSA-2892247|reactome:R-HSA-3769402|reactome:R-HSA-452723|reactome:R-HSA-6785807|reactome:R-HSA-8986944 ensembl:ENSG00000086061(gene)|ensembl:ENST00000330899(transcript)|go:"GO:0001664"(G protein-coupled receptor binding)|go:"GO:0001671"(ATPase activator activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0006457"(protein folding)|go:"GO:0006986"(response to unfolded protein)|go:"GO:0007283"(spermatogenesis)|go:"GO:0009408"(response to heat)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0016020"(membrane)|go:"GO:0030317"(flagellated sperm motility)|go:"GO:0030544"(Hsp70 protein binding)|go:"GO:0030521"(androgen receptor signaling pathway)|go:"GO:0030957"(Tat protein binding)|go:"GO:0031397"(negative regulation of protein ubiquitination)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0042769"(obsolete DNA damage response, detection of DNA damage)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043508"(negative regulation of JUN kinase activity)|go:"GO:0046872"(metal ion binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0050750"(low-density lipoprotein particle receptor binding)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0051087"(chaperone binding)|go:"GO:0051223"(regulation of protein transport)|go:"GO:0055131"(C3HC4-type RING finger domain binding)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070585"(protein localization to mitochondrion)|go:"GO:0098554"(cytoplasmic side of endoplasmic reticulum membrane)|go:"GO:1901998"(toxin transport)|go:"GO:1903748"(negative regulation of establishment of protein localization to mitochondrion)|go:"GO:1905259"(negative regulation of nitrosative stress-induced intrinsic apoptotic signaling pathway)|interpro:IPR001305(Heat shock protein DnaJ, cysteine-rich region)|interpro:IPR001623(Heat shock protein DnaJ, N-terminal)|interpro:IPR002939(Chaperone DnaJ, C-terminal)|interpro:IPR008971(HSP40/DnaJ peptide-binding)|interpro:IPR012724(Chaperone DnaJ)|interpro:IPR018253|interpro:IPR036410|interpro:IPR036869|interpro:IPR044713|mint:P31689|rcsb pdb:2LO1|rcsb pdb:2M6Y|reactome:R-HSA-3371497|rcsb pdb:6E8M|refseq:NP_001530.1 go:"GO:0005634"(nucleus) - - figure legend:ST3 F2C|comment:proteins that were enriched in the induced sample more than 6-fold|dataset:Brain Disease - Neurological Diseases & Disorders|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-daoy)|taxid:9606(Homo sapiens DAOY cerebellar medulloblastoma cell line) - 2020/12/29 2020/12/29 rogid:cn8gYfKDpQc8J2ygnqny32sIyyU9606 rogid:YEHeLHYaG2ON2gwuFfqt9Le1Drg9606 rigid:Cnhili6Os5i+9KsmWx3iqclZGC0 false tandem tag:n-n - - - psi-mi:"MI:0658"(multidimensional protein identification technology) psi-mi:"MI:0658"(multidimensional protein identification technology) uniprotkb:P48431 uniprotkb:Q6P1J9 intact:EBI-6124081|uniprotkb:Q14537|ensembl:ENSP00000323588 intact:EBI-930143|uniprotkb:A6NLZ8|uniprotkb:Q6PK51|uniprotkb:Q96A07|uniprotkb:Q9H245|uniprotkb:Q9H5L7|uniprotkb:B2RBR2|ensembl:ENSP00000356405 psi-mi:sox2_human(display_long)|uniprotkb:SOX2(gene name)|psi-mi:SOX2(display_short) psi-mi:cdc73_human(display_long)|uniprotkb:CDC73(gene name)|psi-mi:CDC73(display_short)|uniprotkb:C1orf28(gene name synonym)|uniprotkb:HRPT2(gene name synonym)|uniprotkb:Cell division cycle protein 73 homolog(gene name synonym)|uniprotkb:Hyperparathyroidism 2 protein(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Cox et al. (2012) pubmed:23667531|imex:IM-28599 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-26574478|imex:IM-28599-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_003097.1|dip:DIP-59913N|ensembl:ENSG00000181449(gene)|ensembl:ENST00000325404(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001649"(osteoblast differentiation)|go:"GO:0001654"(eye development)|go:"GO:0001714"(endodermal cell fate specification)|go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006325"(chromatin organization)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0009611"(response to wounding)|go:"GO:0009653"(anatomical structure morphogenesis)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0021781"(glial cell fate commitment)|go:"GO:0021983"(pituitary gland development)|go:"GO:0021984"(adenohypophysis development)|go:"GO:0022409"(positive regulation of cell-cell adhesion)|go:"GO:0030154"(cell differentiation)|go:"GO:0030900"(forebrain development)|go:"GO:0035019"(somatic stem cell population maintenance)|go:"GO:0035198"(miRNA binding)|go:"GO:0042246"(tissue regeneration)|go:"GO:0043281"(regulation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0043410"(positive regulation of MAPK cascade)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045165"(cell fate commitment)|go:"GO:0045597"(positive regulation of cell differentiation)|go:"GO:0045665"(negative regulation of neuron differentiation)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048839"(inner ear development)|go:"GO:0050680"(negative regulation of epithelial cell proliferation)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0070848"(response to growth factor)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:0097150"(neuronal stem cell population maintenance)|interpro:IPR009071(High mobility group box, HMG)|interpro:IPR022097|interpro:IPR032643|interpro:IPR036910|mint:P48431|rcsb pdb:1O4X|rcsb pdb:2LE4|rcsb pdb:6T7B|rcsb pdb:6T90|rcsb pdb:6WX7|rcsb pdb:6WX8|rcsb pdb:6WX9|rcsb pdb:6YOV|reactome:R-HSA-2892245|reactome:R-HSA-2892247|reactome:R-HSA-3769402|reactome:R-HSA-452723|reactome:R-HSA-6785807|reactome:R-HSA-8986944 refseq:NP_078805.3|dip:DIP-37884N|ensembl:ENSG00000134371(gene)|ensembl:ENST00000367435(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0000993"(RNA polymerase II complex binding)|go:"GO:0001558"(regulation of cell growth)|go:"GO:0001711"(endodermal cell fate commitment)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006368"(transcription elongation from RNA polymerase II promoter)|go:"GO:0006378"(mRNA polyadenylation)|go:"GO:0007049"(cell cycle)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0010390"(histone monoubiquitination)|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0016593"(Cdc73/Paf1 complex)|go:"GO:0019827"(stem cell population maintenance)|go:"GO:0030177"(positive regulation of Wnt signaling pathway)|go:"GO:0031442"(positive regulation of mRNA 3'-end processing)|go:"GO:0031648"(protein destabilization)|go:"GO:0032968"(positive regulation of transcription elongation from RNA polymerase II promoter)|go:"GO:0033523"(histone H2B ubiquitination)|go:"GO:0034402"(recruitment of 3'-end processing factors to RNA polymerase II holoenzyme complex)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0045638"(negative regulation of myeloid cell differentiation)|go:"GO:0048147"(negative regulation of fibroblast proliferation)|go:"GO:0050680"(negative regulation of epithelial cell proliferation)|go:"GO:0071222"(cellular response to lipopolysaccharide)|go:"GO:1902808"(positive regulation of cell cycle G1/S phase transition)|go:"GO:2000134"(negative regulation of G1/S transition of mitotic cell cycle)|interpro:IPR007852(RNA polymerase II accessory factor, Cdc73)|interpro:IPR031336|interpro:IPR032041|interpro:IPR038103|mint:Q6P1J9|rcsb pdb:5YDE|rcsb pdb:5YDF|rcsb pdb:6TED|reactome:R-HSA-112382|reactome:R-HSA-201722|reactome:R-HSA-5632684|reactome:R-HSA-674695|reactome:R-HSA-75955|reactome:R-HSA-8866654 go:"GO:0005634"(nucleus) - - figure legend:ST3 F2C|comment:proteins that were enriched in the induced sample more than 6-fold|dataset:Brain Disease - Neurological Diseases & Disorders|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-daoy)|taxid:9606(Homo sapiens DAOY cerebellar medulloblastoma cell line) - 2020/12/29 2020/12/29 rogid:cn8gYfKDpQc8J2ygnqny32sIyyU9606 rogid:nuJ2kK0petj8iBr17I2BQzxcVmE9606 rigid:Cnhili6Os5i+9KsmWx3iqclZGC0 false tandem tag:n-n - - - psi-mi:"MI:0658"(multidimensional protein identification technology) psi-mi:"MI:0658"(multidimensional protein identification technology) uniprotkb:P48431 uniprotkb:O95816 intact:EBI-6124081|uniprotkb:Q14537|ensembl:ENSP00000323588 intact:EBI-355275|uniprotkb:Q08AS9|uniprotkb:Q6FID0|uniprotkb:B4DXE2|ensembl:ENSP00000359727|intact:EBI-11068407 psi-mi:sox2_human(display_long)|uniprotkb:SOX2(gene name)|psi-mi:SOX2(display_short) psi-mi:bag2_human(display_long)|uniprotkb:BAG2(gene name)|psi-mi:BAG2(display_short)|uniprotkb:Bcl-2-associated athanogene 2(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Cox et al. (2012) pubmed:23667531|imex:IM-28599 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-26574478|imex:IM-28599-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_003097.1|dip:DIP-59913N|ensembl:ENSG00000181449(gene)|ensembl:ENST00000325404(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001649"(osteoblast differentiation)|go:"GO:0001654"(eye development)|go:"GO:0001714"(endodermal cell fate specification)|go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006325"(chromatin organization)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0009611"(response to wounding)|go:"GO:0009653"(anatomical structure morphogenesis)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0021781"(glial cell fate commitment)|go:"GO:0021983"(pituitary gland development)|go:"GO:0021984"(adenohypophysis development)|go:"GO:0022409"(positive regulation of cell-cell adhesion)|go:"GO:0030154"(cell differentiation)|go:"GO:0030900"(forebrain development)|go:"GO:0035019"(somatic stem cell population maintenance)|go:"GO:0035198"(miRNA binding)|go:"GO:0042246"(tissue regeneration)|go:"GO:0043281"(regulation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0043410"(positive regulation of MAPK cascade)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045165"(cell fate commitment)|go:"GO:0045597"(positive regulation of cell differentiation)|go:"GO:0045665"(negative regulation of neuron differentiation)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048839"(inner ear development)|go:"GO:0050680"(negative regulation of epithelial cell proliferation)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0070848"(response to growth factor)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:0097150"(neuronal stem cell population maintenance)|interpro:IPR009071(High mobility group box, HMG)|interpro:IPR022097|interpro:IPR032643|interpro:IPR036910|mint:P48431|rcsb pdb:1O4X|rcsb pdb:2LE4|rcsb pdb:6T7B|rcsb pdb:6T90|rcsb pdb:6WX7|rcsb pdb:6WX8|rcsb pdb:6WX9|rcsb pdb:6YOV|reactome:R-HSA-2892245|reactome:R-HSA-2892247|reactome:R-HSA-3769402|reactome:R-HSA-452723|reactome:R-HSA-6785807|reactome:R-HSA-8986944 refseq:NP_004273.1|refseq:XP_011513301.1|refseq:XP_005249547.1|ensembl:ENSG00000112208(gene)|ensembl:ENST00000370693(transcript)|go:"GO:0030424"(axon)|go:"GO:0030425"(dendrite)|go:"GO:0031072"(heat shock protein binding)|go:"GO:0031397"(negative regulation of protein ubiquitination)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032091"(negative regulation of protein binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0048156"(tau protein binding)|go:"GO:0050821"(protein stabilization)|go:"GO:0000774"(adenyl-nucleotide exchange factor activity)|go:"GO:0005829"(cytosol)|go:"GO:0006457"(protein folding)|go:"GO:0010954"(positive regulation of protein processing)|go:"GO:0019538"(protein metabolic process)|go:"GO:0051087"(chaperone binding)|go:"GO:0101031"(chaperone complex)|go:"GO:1901588"(dendritic microtubule)|go:"GO:1901800"(positive regulation of proteasomal protein catabolic process)|go:"GO:1904667"(negative regulation of ubiquitin protein ligase activity)|interpro:IPR003103(Apoptosis regulator Bcl-2 protein, BAG)|interpro:IPR037689|mint:O95816|reactome:R-HSA-3371453|refseq:XP_011513300.1 go:"GO:0005634"(nucleus) - - figure legend:ST3 F2C|comment:proteins that were enriched in the induced sample more than 6-fold|dataset:Brain Disease - Neurological Diseases & Disorders|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-daoy)|taxid:9606(Homo sapiens DAOY cerebellar medulloblastoma cell line) - 2020/12/29 2020/12/29 rogid:cn8gYfKDpQc8J2ygnqny32sIyyU9606 rogid:nBGGBIQc/3P0mwp7N/XuTGLOrg89606 rigid:Cnhili6Os5i+9KsmWx3iqclZGC0 false tandem tag:n-n - - - psi-mi:"MI:0658"(multidimensional protein identification technology) psi-mi:"MI:0658"(multidimensional protein identification technology) uniprotkb:P48431 uniprotkb:O95347 intact:EBI-6124081|uniprotkb:Q14537|ensembl:ENSP00000323588 intact:EBI-355822|intact:EBI-1058371|uniprotkb:Q9P1P2|uniprotkb:Q6IEE0|ensembl:ENSP00000286398|ensembl:ENSP00000363919|ensembl:ENSP00000363925 psi-mi:sox2_human(display_long)|uniprotkb:SOX2(gene name)|psi-mi:SOX2(display_short) psi-mi:smc2_human(display_long)|uniprotkb:PRO0324(orf name)|uniprotkb:SMC2(gene name)|psi-mi:SMC2(display_short)|uniprotkb:CAPE(gene name synonym)|uniprotkb:SMC2L1(gene name synonym)|uniprotkb:Chromosome-associated protein E(gene name synonym)|uniprotkb:XCAP-E homolog(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Cox et al. (2012) pubmed:23667531|imex:IM-28599 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-26574478|imex:IM-28599-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_003097.1|dip:DIP-59913N|ensembl:ENSG00000181449(gene)|ensembl:ENST00000325404(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001649"(osteoblast differentiation)|go:"GO:0001654"(eye development)|go:"GO:0001714"(endodermal cell fate specification)|go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006325"(chromatin organization)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0009611"(response to wounding)|go:"GO:0009653"(anatomical structure morphogenesis)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0021781"(glial cell fate commitment)|go:"GO:0021983"(pituitary gland development)|go:"GO:0021984"(adenohypophysis development)|go:"GO:0022409"(positive regulation of cell-cell adhesion)|go:"GO:0030154"(cell differentiation)|go:"GO:0030900"(forebrain development)|go:"GO:0035019"(somatic stem cell population maintenance)|go:"GO:0035198"(miRNA binding)|go:"GO:0042246"(tissue regeneration)|go:"GO:0043281"(regulation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0043410"(positive regulation of MAPK cascade)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045165"(cell fate commitment)|go:"GO:0045597"(positive regulation of cell differentiation)|go:"GO:0045665"(negative regulation of neuron differentiation)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048839"(inner ear development)|go:"GO:0050680"(negative regulation of epithelial cell proliferation)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0070848"(response to growth factor)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:0097150"(neuronal stem cell population maintenance)|interpro:IPR009071(High mobility group box, HMG)|interpro:IPR022097|interpro:IPR032643|interpro:IPR036910|mint:P48431|rcsb pdb:1O4X|rcsb pdb:2LE4|rcsb pdb:6T7B|rcsb pdb:6T90|rcsb pdb:6WX7|rcsb pdb:6WX8|rcsb pdb:6WX9|rcsb pdb:6YOV|reactome:R-HSA-2892245|reactome:R-HSA-2892247|reactome:R-HSA-3769402|reactome:R-HSA-452723|reactome:R-HSA-6785807|reactome:R-HSA-8986944 refseq:NP_001036015.1|refseq:NP_001036016.1|refseq:NP_006435.2|refseq:XP_011516451.1|refseq:XP_011516455.1|refseq:XP_011516450.1|refseq:NP_001252531.1|refseq:XP_006716996.1|refseq:XP_016869695.1|refseq:XP_016869696.1|refseq:XP_016869697.1|dip:DIP-35422N|ensembl:ENSG00000136824(gene)|ensembl:ENST00000286398(transcript)|ensembl:ENST00000374787(transcript)|ensembl:ENST00000374793(transcript)|go:"GO:0000228"(nuclear chromosome)|go:"GO:0000793"(condensed chromosome)|go:"GO:0000796"(condensin complex)|go:"GO:0003682"(chromatin binding)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0007076"(mitotic chromosome condensation)|go:"GO:0010032"(meiotic chromosome condensation)|go:"GO:0045132"(meiotic chromosome segregation)|go:"GO:0051301"(cell division)|go:"GO:0051383"(kinetochore organization)|go:"GO:0070062"(extracellular exosome)|interpro:IPR003395(RecF/RecN/SMC protein, N-terminal)|interpro:IPR010935(SMCs flexible hinge)|interpro:IPR024704|interpro:IPR027120|interpro:IPR027417|interpro:IPR036277|mint:O95347|rcsb pdb:4U4P|reactome:R-HSA-2299718|reactome:R-HSA-2514853 go:"GO:0005634"(nucleus) - - figure legend:ST3 F2C|comment:proteins that were enriched in the induced sample more than 6-fold|dataset:Brain Disease - Neurological Diseases & Disorders|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-daoy)|taxid:9606(Homo sapiens DAOY cerebellar medulloblastoma cell line) - 2020/12/29 2020/12/29 rogid:cn8gYfKDpQc8J2ygnqny32sIyyU9606 rogid:k7RHRDmgiucuAOIfh8vjbqnlv3E9606 rigid:Cnhili6Os5i+9KsmWx3iqclZGC0 false tandem tag:n-n - - - psi-mi:"MI:0658"(multidimensional protein identification technology) psi-mi:"MI:0658"(multidimensional protein identification technology) uniprotkb:P48431 uniprotkb:P09543 intact:EBI-6124081|uniprotkb:Q14537|ensembl:ENSP00000323588 intact:EBI-1059219|intact:EBI-1188262|ensembl:ENSP00000377470 psi-mi:sox2_human(display_long)|uniprotkb:SOX2(gene name)|psi-mi:SOX2(display_short) psi-mi:cn37_human(display_long)|uniprotkb:CNP(gene name)|psi-mi:CNP(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Cox et al. (2012) pubmed:23667531|imex:IM-28599 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-26574478|imex:IM-28599-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_003097.1|dip:DIP-59913N|ensembl:ENSG00000181449(gene)|ensembl:ENST00000325404(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001649"(osteoblast differentiation)|go:"GO:0001654"(eye development)|go:"GO:0001714"(endodermal cell fate specification)|go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006325"(chromatin organization)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0009611"(response to wounding)|go:"GO:0009653"(anatomical structure morphogenesis)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0021781"(glial cell fate commitment)|go:"GO:0021983"(pituitary gland development)|go:"GO:0021984"(adenohypophysis development)|go:"GO:0022409"(positive regulation of cell-cell adhesion)|go:"GO:0030154"(cell differentiation)|go:"GO:0030900"(forebrain development)|go:"GO:0035019"(somatic stem cell population maintenance)|go:"GO:0035198"(miRNA binding)|go:"GO:0042246"(tissue regeneration)|go:"GO:0043281"(regulation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0043410"(positive regulation of MAPK cascade)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045165"(cell fate commitment)|go:"GO:0045597"(positive regulation of cell differentiation)|go:"GO:0045665"(negative regulation of neuron differentiation)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048839"(inner ear development)|go:"GO:0050680"(negative regulation of epithelial cell proliferation)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0070848"(response to growth factor)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:0097150"(neuronal stem cell population maintenance)|interpro:IPR009071(High mobility group box, HMG)|interpro:IPR022097|interpro:IPR032643|interpro:IPR036910|mint:P48431|rcsb pdb:1O4X|rcsb pdb:2LE4|rcsb pdb:6T7B|rcsb pdb:6T90|rcsb pdb:6WX7|rcsb pdb:6WX8|rcsb pdb:6WX9|rcsb pdb:6YOV|reactome:R-HSA-2892245|reactome:R-HSA-2892247|reactome:R-HSA-3769402|reactome:R-HSA-452723|reactome:R-HSA-6785807|reactome:R-HSA-8986944 refseq:NP_149124.3|refseq:XP_011522642.1|ensembl:ENSG00000173786(gene)|ensembl:ENST00000393892(transcript)|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0004113"(2',3'-cyclic-nucleotide 3'-phosphodiesterase activity)|go:"GO:0005615"(extracellular space)|go:"GO:0005737"(cytoplasm)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005874"(microtubule)|go:"GO:0005886"(plasma membrane)|go:"GO:0005902"(microvillus)|go:"GO:0007268"(chemical synaptic transmission)|go:"GO:0007409"(axonogenesis)|go:"GO:0007568"(aging)|go:"GO:0008344"(adult locomotory behavior)|go:"GO:0009214"(cyclic nucleotide catabolic process)|go:"GO:0009636"(response to toxic substance)|go:"GO:0016020"(membrane)|go:"GO:0021762"(substantia nigra development)|go:"GO:0030551"(cyclic nucleotide binding)|go:"GO:0030900"(forebrain development)|go:"GO:0031143"(pseudopodium)|go:"GO:0032496"(response to lipopolysaccharide)|go:"GO:0035748"(myelin sheath abaxonal region)|go:"GO:0035749"(myelin sheath adaxonal region)|go:"GO:0042470"(melanosome)|go:"GO:0045202"(synapse)|go:"GO:0046902"(regulation of mitochondrial membrane permeability)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0048709"(oligodendrocyte differentiation)|go:"GO:0070062"(extracellular exosome)|interpro:IPR008431(Cyclic nucleotide phosphodiesterase)|interpro:IPR009097(RNA ligase/cyclic nucleotide phosphodiesterase)|interpro:IPR027417|mint:P09543|rcsb pdb:1WOJ|go:"GO:0003723"(RNA binding)|refseq:NP_001317145.1 go:"GO:0005634"(nucleus) - - figure legend:ST3 F2C|comment:proteins that were enriched in the induced sample more than 6-fold|dataset:Brain Disease - Neurological Diseases & Disorders|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-daoy)|taxid:9606(Homo sapiens DAOY cerebellar medulloblastoma cell line) - 2020/12/29 2020/12/29 rogid:cn8gYfKDpQc8J2ygnqny32sIyyU9606 rogid:TpzVM789s3qQKK7B00Vo92s31bY9606 rigid:Cnhili6Os5i+9KsmWx3iqclZGC0 false tandem tag:n-n - - - psi-mi:"MI:0658"(multidimensional protein identification technology) psi-mi:"MI:0658"(multidimensional protein identification technology) uniprotkb:P48431 uniprotkb:O75925 intact:EBI-6124081|uniprotkb:Q14537|ensembl:ENSP00000323588 intact:EBI-629434|uniprotkb:Q147X4|uniprotkb:Q99751|uniprotkb:Q9UN02|uniprotkb:B2RB67|uniprotkb:B3KSY9|ensembl:ENSP00000249636|intact:EBI-28970067|uniprotkb:C5J4B4 psi-mi:sox2_human(display_long)|uniprotkb:SOX2(gene name)|psi-mi:SOX2(display_short) psi-mi:pias1_human(display_long)|uniprotkb:Protein inhibitor of activated STAT protein 1(gene name synonym)|uniprotkb:Gu-binding protein(gene name synonym)|uniprotkb:RNA helicase II-binding protein(gene name synonym)|uniprotkb:DEAD/H box-binding protein 1(gene name synonym)|uniprotkb:PIAS1(gene name)|psi-mi:PIAS1(display_short)|uniprotkb:DDXBP1(gene name synonym)|uniprotkb:E3 SUMO-protein transferase PIAS1(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Cox et al. (2012) pubmed:23667531|imex:IM-28599 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-26574478|imex:IM-28599-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_003097.1|dip:DIP-59913N|ensembl:ENSG00000181449(gene)|ensembl:ENST00000325404(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001649"(osteoblast differentiation)|go:"GO:0001654"(eye development)|go:"GO:0001714"(endodermal cell fate specification)|go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006325"(chromatin organization)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0009611"(response to wounding)|go:"GO:0009653"(anatomical structure morphogenesis)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0021781"(glial cell fate commitment)|go:"GO:0021983"(pituitary gland development)|go:"GO:0021984"(adenohypophysis development)|go:"GO:0022409"(positive regulation of cell-cell adhesion)|go:"GO:0030154"(cell differentiation)|go:"GO:0030900"(forebrain development)|go:"GO:0035019"(somatic stem cell population maintenance)|go:"GO:0035198"(miRNA binding)|go:"GO:0042246"(tissue regeneration)|go:"GO:0043281"(regulation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0043410"(positive regulation of MAPK cascade)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045165"(cell fate commitment)|go:"GO:0045597"(positive regulation of cell differentiation)|go:"GO:0045665"(negative regulation of neuron differentiation)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048839"(inner ear development)|go:"GO:0050680"(negative regulation of epithelial cell proliferation)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0070848"(response to growth factor)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:0097150"(neuronal stem cell population maintenance)|interpro:IPR009071(High mobility group box, HMG)|interpro:IPR022097|interpro:IPR032643|interpro:IPR036910|mint:P48431|rcsb pdb:1O4X|rcsb pdb:2LE4|rcsb pdb:6T7B|rcsb pdb:6T90|rcsb pdb:6WX7|rcsb pdb:6WX8|rcsb pdb:6WX9|rcsb pdb:6YOV|reactome:R-HSA-2892245|reactome:R-HSA-2892247|reactome:R-HSA-3769402|reactome:R-HSA-452723|reactome:R-HSA-6785807|reactome:R-HSA-8986944 refseq:NP_001307616.1|refseq:NP_057250.1|ensembl:ENSP00000249636|ensembl:ENST00000545237|ensembl:ENSP00000438574|ensembl:ENSG00000033800(gene)|ensembl:ENST00000249636(transcript)|go:"GO:0000082"(G1/S transition of mitotic cell cycle)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0003677"(DNA binding)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007259"(receptor signaling pathway via JAK-STAT)|go:"GO:0007283"(spermatogenesis)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008270"(zinc ion binding)|go:"GO:0008542"(visual learning)|go:"GO:0016605"(PML body)|go:"GO:0016607"(nuclear speck)|go:"GO:0016925"(protein sumoylation)|go:"GO:0019789"(SUMO transferase activity)|go:"GO:0019899"(enzyme binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032436"(positive regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0033235"(positive regulation of protein sumoylation)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0045444"(fat cell differentiation)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0051152"(positive regulation of smooth muscle cell differentiation)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:0061665"(SUMO ligase activity)|go:"GO:0065004"(protein-DNA complex assembly)|interpro:IPR003034(DNA-binding SAP)|interpro:IPR004181(Zinc finger, MIZ-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR023321|interpro:IPR027226|interpro:IPR036361|interpro:IPR038654|mint:O75925|go:"GO:0042127"(regulation of cell population proliferation)|rcsb pdb:1V66|reactome:R-HSA-3108214|reactome:R-HSA-3232118|reactome:R-HSA-3232142|reactome:R-HSA-3899300|reactome:R-HSA-4090294|reactome:R-HSA-4551638|reactome:R-HSA-5696395|reactome:R-HSA-877312|refseq:XP_016878177.1|dip:DIP-5970N go:"GO:0005634"(nucleus) - - figure legend:ST3 F2C|comment:proteins that were enriched in the induced sample more than 6-fold|dataset:Brain Disease - Neurological Diseases & Disorders|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-daoy)|taxid:9606(Homo sapiens DAOY cerebellar medulloblastoma cell line) - 2020/12/29 2020/12/29 rogid:cn8gYfKDpQc8J2ygnqny32sIyyU9606 rogid:SJB9TG4K6p8GSZwh0MNanj6cGt49606 rigid:Cnhili6Os5i+9KsmWx3iqclZGC0 false tandem tag:n-n - - - psi-mi:"MI:0658"(multidimensional protein identification technology) psi-mi:"MI:0658"(multidimensional protein identification technology) uniprotkb:P48431 uniprotkb:P62310 intact:EBI-6124081|uniprotkb:Q14537|ensembl:ENSP00000323588 intact:EBI-348239|ensembl:ENSP00000302160|uniprotkb:Q9Y4Z1|uniprotkb:Q6IAH0 psi-mi:sox2_human(display_long)|uniprotkb:SOX2(gene name)|psi-mi:SOX2(display_short) psi-mi:lsm3_human(display_long)|uniprotkb:MDS017(orf name)|uniprotkb:LSM3(gene name)|psi-mi:LSM3(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Cox et al. (2012) pubmed:23667531|imex:IM-28599 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-26574478|imex:IM-28599-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_003097.1|dip:DIP-59913N|ensembl:ENSG00000181449(gene)|ensembl:ENST00000325404(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001649"(osteoblast differentiation)|go:"GO:0001654"(eye development)|go:"GO:0001714"(endodermal cell fate specification)|go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006325"(chromatin organization)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0009611"(response to wounding)|go:"GO:0009653"(anatomical structure morphogenesis)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0021781"(glial cell fate commitment)|go:"GO:0021983"(pituitary gland development)|go:"GO:0021984"(adenohypophysis development)|go:"GO:0022409"(positive regulation of cell-cell adhesion)|go:"GO:0030154"(cell differentiation)|go:"GO:0030900"(forebrain development)|go:"GO:0035019"(somatic stem cell population maintenance)|go:"GO:0035198"(miRNA binding)|go:"GO:0042246"(tissue regeneration)|go:"GO:0043281"(regulation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0043410"(positive regulation of MAPK cascade)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045165"(cell fate commitment)|go:"GO:0045597"(positive regulation of cell differentiation)|go:"GO:0045665"(negative regulation of neuron differentiation)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048839"(inner ear development)|go:"GO:0050680"(negative regulation of epithelial cell proliferation)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0070848"(response to growth factor)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:0097150"(neuronal stem cell population maintenance)|interpro:IPR009071(High mobility group box, HMG)|interpro:IPR022097|interpro:IPR032643|interpro:IPR036910|mint:P48431|rcsb pdb:1O4X|rcsb pdb:2LE4|rcsb pdb:6T7B|rcsb pdb:6T90|rcsb pdb:6WX7|rcsb pdb:6WX8|rcsb pdb:6WX9|rcsb pdb:6YOV|reactome:R-HSA-2892245|reactome:R-HSA-2892247|reactome:R-HSA-3769402|reactome:R-HSA-452723|reactome:R-HSA-6785807|reactome:R-HSA-8986944 ensembl:ENSG00000170860(gene)|ensembl:ENST00000306024(transcript)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0000932"(P-body)|go:"GO:0000956"(nuclear-transcribed mRNA catabolic process)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005688"(U6 snRNP)|go:"GO:0005829"(cytosol)|go:"GO:0006397"(mRNA processing)|go:"GO:0030629"(U6 snRNA 3'-end binding)|go:"GO:0033962"(P-body assembly)|go:"GO:0046540"(U4/U6 x U5 tri-snRNP complex)|go:"GO:0071011"(precatalytic spliceosome)|go:"GO:0071013"(catalytic step 2 spliceosome)|go:"GO:0120115"(Lsm2-8 complex)|go:"GO:0071005"(U2-type precatalytic spliceosome)|go:"GO:1990726"(Lsm1-7-Pat1 complex)|interpro:IPR001163(Like-Sm ribonucleoprotein, core)|interpro:IPR010920(Like-Sm ribonucleoprotein-related, core)|interpro:IPR034105|interpro:IPR040002|mint:P62310|rcsb pdb:3JCR|rcsb pdb:5O9Z|rcsb pdb:6AH0|rcsb pdb:6AHD|rcsb pdb:6QW6|rcsb pdb:6QX9|rcsb pdb:7ABG|reactome:R-HSA-430039|reactome:R-HSA-72163|refseq:NP_055278.1|dip:DIP-31218N go:"GO:0005634"(nucleus) - - figure legend:ST3 F2C|comment:proteins that were enriched in the induced sample more than 6-fold|dataset:Brain Disease - Neurological Diseases & Disorders|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-daoy)|taxid:9606(Homo sapiens DAOY cerebellar medulloblastoma cell line) - 2020/12/29 2020/12/29 rogid:cn8gYfKDpQc8J2ygnqny32sIyyU9606 rogid:+OnRI9eJcsd1xJe+cUCP7Y/9tt09606 rigid:Cnhili6Os5i+9KsmWx3iqclZGC0 false tandem tag:n-n - - - psi-mi:"MI:0658"(multidimensional protein identification technology) psi-mi:"MI:0658"(multidimensional protein identification technology) uniprotkb:P48431 uniprotkb:O75190 intact:EBI-6124081|uniprotkb:Q14537|ensembl:ENSP00000323588 intact:EBI-1053164|uniprotkb:A4D232|uniprotkb:O95806|uniprotkb:A8KAG0|uniprotkb:B4DN73|uniprotkb:E9PCZ2|uniprotkb:Q53EN8|uniprotkb:Q59EF2|uniprotkb:Q6FIC8|uniprotkb:Q75MA2|uniprotkb:Q9UIK6|uniprotkb:A8K7D8|ensembl:ENSP00000262177 psi-mi:sox2_human(display_long)|uniprotkb:SOX2(gene name)|psi-mi:SOX2(display_short) psi-mi:dnjb6_human(display_long)|uniprotkb:Heat shock protein J2(gene name synonym)|uniprotkb:MSJ-1(gene name synonym)|uniprotkb:HHDJ1(gene name synonym)|uniprotkb:DNAJB6(gene name)|psi-mi:DNAJB6(display_short)|uniprotkb:HSJ2(gene name synonym)|uniprotkb:MSJ1(gene name synonym)|uniprotkb:MRJ(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Cox et al. (2012) pubmed:23667531|imex:IM-28599 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-26574478|imex:IM-28599-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_003097.1|dip:DIP-59913N|ensembl:ENSG00000181449(gene)|ensembl:ENST00000325404(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001649"(osteoblast differentiation)|go:"GO:0001654"(eye development)|go:"GO:0001714"(endodermal cell fate specification)|go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006325"(chromatin organization)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0009611"(response to wounding)|go:"GO:0009653"(anatomical structure morphogenesis)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0021781"(glial cell fate commitment)|go:"GO:0021983"(pituitary gland development)|go:"GO:0021984"(adenohypophysis development)|go:"GO:0022409"(positive regulation of cell-cell adhesion)|go:"GO:0030154"(cell differentiation)|go:"GO:0030900"(forebrain development)|go:"GO:0035019"(somatic stem cell population maintenance)|go:"GO:0035198"(miRNA binding)|go:"GO:0042246"(tissue regeneration)|go:"GO:0043281"(regulation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0043410"(positive regulation of MAPK cascade)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045165"(cell fate commitment)|go:"GO:0045597"(positive regulation of cell differentiation)|go:"GO:0045665"(negative regulation of neuron differentiation)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048839"(inner ear development)|go:"GO:0050680"(negative regulation of epithelial cell proliferation)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0070848"(response to growth factor)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:0097150"(neuronal stem cell population maintenance)|interpro:IPR009071(High mobility group box, HMG)|interpro:IPR022097|interpro:IPR032643|interpro:IPR036910|mint:P48431|rcsb pdb:1O4X|rcsb pdb:2LE4|rcsb pdb:6T7B|rcsb pdb:6T90|rcsb pdb:6WX7|rcsb pdb:6WX8|rcsb pdb:6WX9|rcsb pdb:6YOV|reactome:R-HSA-2892245|reactome:R-HSA-2892247|reactome:R-HSA-3769402|reactome:R-HSA-452723|reactome:R-HSA-6785807|reactome:R-HSA-8986944 refseq:NP_005485.1|refseq:NP_490647.1|ensembl:ENSG00000105993(gene)|ensembl:ENST00000262177(transcript)|go:"GO:0001671"(ATPase activator activity)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006457"(protein folding)|go:"GO:0045109"(intermediate filament organization)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0051087"(chaperone binding)|go:"GO:0060710"(chorio-allantoic fusion)|go:"GO:0060715"(syncytiotrophoblast cell differentiation involved in labyrinthine layer development)|go:"GO:0060717"(chorion development)|go:"GO:0090084"(negative regulation of inclusion body assembly)|go:"GO:1900034"(regulation of cellular response to heat)|interpro:IPR001623(Heat shock protein DnaJ, N-terminal)|interpro:IPR018253|interpro:IPR036869|mint:O75190|rcsb pdb:6U3R|rcsb pdb:6U3S|rcsb pdb:7JSQ|reactome:R-HSA-3371453|go:"GO:0016020"(membrane)|go:"GO:0030018"(Z disc)|go:"GO:0030036"(actin cytoskeleton organization)|go:"GO:0030198"(extracellular matrix organization)|go:"GO:0031072"(heat shock protein binding)|go:"GO:0032880"(regulation of protein localization)|go:"GO:0034504"(protein localization to nucleus)|go:"GO:0042802"(identical protein binding)|go:"GO:0043154"(negative regulation of cysteine-type endopeptidase activity involved in apoptotic process) go:"GO:0005634"(nucleus) - - figure legend:ST3 F2C|comment:proteins that were enriched in the induced sample more than 6-fold|dataset:Brain Disease - Neurological Diseases & Disorders|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-daoy)|taxid:9606(Homo sapiens DAOY cerebellar medulloblastoma cell line) - 2020/12/29 2020/12/29 rogid:cn8gYfKDpQc8J2ygnqny32sIyyU9606 rogid:6X99Uu2SBlHsGCv61ZbwSz4LRp89606 rigid:Cnhili6Os5i+9KsmWx3iqclZGC0 false tandem tag:n-n - - - psi-mi:"MI:0658"(multidimensional protein identification technology) psi-mi:"MI:0658"(multidimensional protein identification technology) uniprotkb:P48431 uniprotkb:Q8N201 intact:EBI-6124081|uniprotkb:Q14537|ensembl:ENSP00000323588 intact:EBI-724549|uniprotkb:A6NJ44|uniprotkb:Q6NT70|uniprotkb:Q6UX74|uniprotkb:Q8WV40|uniprotkb:Q96D36|uniprotkb:Q9NTD1|uniprotkb:Q9P2A8|uniprotkb:Q9Y3W8|ensembl:ENSP00000385722 psi-mi:sox2_human(display_long)|uniprotkb:SOX2(gene name)|psi-mi:SOX2(display_short) psi-mi:int1_human(display_long)|uniprotkb:INTS1(gene name)|psi-mi:INTS1(display_short)|uniprotkb:KIAA1440(gene name synonym)|uniprotkb:UNQ1821/PRO3434(orf name) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Cox et al. (2012) pubmed:23667531|imex:IM-28599 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-26574478|imex:IM-28599-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_003097.1|dip:DIP-59913N|ensembl:ENSG00000181449(gene)|ensembl:ENST00000325404(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001649"(osteoblast differentiation)|go:"GO:0001654"(eye development)|go:"GO:0001714"(endodermal cell fate specification)|go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006325"(chromatin organization)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0009611"(response to wounding)|go:"GO:0009653"(anatomical structure morphogenesis)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0021781"(glial cell fate commitment)|go:"GO:0021983"(pituitary gland development)|go:"GO:0021984"(adenohypophysis development)|go:"GO:0022409"(positive regulation of cell-cell adhesion)|go:"GO:0030154"(cell differentiation)|go:"GO:0030900"(forebrain development)|go:"GO:0035019"(somatic stem cell population maintenance)|go:"GO:0035198"(miRNA binding)|go:"GO:0042246"(tissue regeneration)|go:"GO:0043281"(regulation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0043410"(positive regulation of MAPK cascade)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045165"(cell fate commitment)|go:"GO:0045597"(positive regulation of cell differentiation)|go:"GO:0045665"(negative regulation of neuron differentiation)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048839"(inner ear development)|go:"GO:0050680"(negative regulation of epithelial cell proliferation)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0070848"(response to growth factor)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:0097150"(neuronal stem cell population maintenance)|interpro:IPR009071(High mobility group box, HMG)|interpro:IPR022097|interpro:IPR032643|interpro:IPR036910|mint:P48431|rcsb pdb:1O4X|rcsb pdb:2LE4|rcsb pdb:6T7B|rcsb pdb:6T90|rcsb pdb:6WX7|rcsb pdb:6WX8|rcsb pdb:6WX9|rcsb pdb:6YOV|reactome:R-HSA-2892245|reactome:R-HSA-2892247|reactome:R-HSA-3769402|reactome:R-HSA-452723|reactome:R-HSA-6785807|reactome:R-HSA-8986944 refseq:NP_001073922.2|ensembl:ENSG00000164880(gene)|ensembl:ENST00000404767(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016180"(snRNA processing)|go:"GO:0031965"(nuclear membrane)|go:"GO:0032039"(integrator complex)|go:"GO:0034474"(U2 snRNA 3'-end processing)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR022145|interpro:IPR038902|mint:Q8N201|rcsb pdb:7CUN|reactome:R-HSA-6807505|dip:DIP-48476N go:"GO:0005634"(nucleus) - - figure legend:ST3 F2C|comment:proteins that were enriched in the induced sample more than 6-fold|dataset:Brain Disease - Neurological Diseases & Disorders|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-daoy)|taxid:9606(Homo sapiens DAOY cerebellar medulloblastoma cell line) - 2020/12/29 2020/12/29 rogid:cn8gYfKDpQc8J2ygnqny32sIyyU9606 rogid:kjJ0Sb3GOWfMXGcrxanGTX+f0VU9606 rigid:Cnhili6Os5i+9KsmWx3iqclZGC0 false tandem tag:n-n - - - psi-mi:"MI:0658"(multidimensional protein identification technology) psi-mi:"MI:0658"(multidimensional protein identification technology) uniprotkb:P48431 uniprotkb:Q96KQ7 intact:EBI-6124081|uniprotkb:Q14537|ensembl:ENSP00000323588 intact:EBI-744366|uniprotkb:B0UZY2|uniprotkb:Q14349|uniprotkb:Q6PK06|uniprotkb:Q96MH5|uniprotkb:Q96QD0|uniprotkb:Q9UQL8|uniprotkb:Q9Y331|uniprotkb:Q5JQ92|uniprotkb:Q5JP83|uniprotkb:Q5JQA1|uniprotkb:Q5JQG3|ensembl:ENSP00000364687|ensembl:ENSP00000372864|ensembl:ENSP00000392305|ensembl:ENSP00000396119|ensembl:ENSP00000406110|ensembl:ENSP00000416957 psi-mi:sox2_human(display_long)|uniprotkb:SOX2(gene name)|psi-mi:SOX2(display_short) psi-mi:ehmt2_human(display_long)|uniprotkb:KMT1C(gene name synonym)|uniprotkb:Histone H3-K9 methyltransferase 3(gene name synonym)|uniprotkb:Euchromatic histone-lysine N-methyltransferase 2(gene name synonym)|uniprotkb:HLA-B-associated transcript 8(gene name synonym)|uniprotkb:Protein G9a(gene name synonym)|uniprotkb:Lysine N-methyltransferase 1C(gene name synonym)|uniprotkb:EHMT2(gene name)|psi-mi:EHMT2(display_short)|uniprotkb:BAT8(gene name synonym)|uniprotkb:G9A(gene name synonym)|uniprotkb:NG36(gene name synonym)|uniprotkb:C6orf30(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Cox et al. (2012) pubmed:23667531|imex:IM-28599 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-26574478|imex:IM-28599-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_003097.1|dip:DIP-59913N|ensembl:ENSG00000181449(gene)|ensembl:ENST00000325404(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001649"(osteoblast differentiation)|go:"GO:0001654"(eye development)|go:"GO:0001714"(endodermal cell fate specification)|go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006325"(chromatin organization)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0009611"(response to wounding)|go:"GO:0009653"(anatomical structure morphogenesis)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0021781"(glial cell fate commitment)|go:"GO:0021983"(pituitary gland development)|go:"GO:0021984"(adenohypophysis development)|go:"GO:0022409"(positive regulation of cell-cell adhesion)|go:"GO:0030154"(cell differentiation)|go:"GO:0030900"(forebrain development)|go:"GO:0035019"(somatic stem cell population maintenance)|go:"GO:0035198"(miRNA binding)|go:"GO:0042246"(tissue regeneration)|go:"GO:0043281"(regulation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0043410"(positive regulation of MAPK cascade)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045165"(cell fate commitment)|go:"GO:0045597"(positive regulation of cell differentiation)|go:"GO:0045665"(negative regulation of neuron differentiation)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048839"(inner ear development)|go:"GO:0050680"(negative regulation of epithelial cell proliferation)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0070848"(response to growth factor)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:0097150"(neuronal stem cell population maintenance)|interpro:IPR009071(High mobility group box, HMG)|interpro:IPR022097|interpro:IPR032643|interpro:IPR036910|mint:P48431|rcsb pdb:1O4X|rcsb pdb:2LE4|rcsb pdb:6T7B|rcsb pdb:6T90|rcsb pdb:6WX7|rcsb pdb:6WX8|rcsb pdb:6WX9|rcsb pdb:6YOV|reactome:R-HSA-2892245|reactome:R-HSA-2892247|reactome:R-HSA-3769402|reactome:R-HSA-452723|reactome:R-HSA-6785807|reactome:R-HSA-8986944 refseq:NP_006700.3|refseq:NP_079532.5|interpro:IPR043550|mint:Q96KQ7|rcsb pdb:2O8J|rcsb pdb:3DM1|rcsb pdb:3K5K|rcsb pdb:3RJW|rcsb pdb:4NVQ|rcsb pdb:5JHN|rcsb pdb:5JIN|rcsb pdb:5JIY|rcsb pdb:5JJ0|rcsb pdb:5T0K|rcsb pdb:5T0M|rcsb pdb:5TTF|rcsb pdb:5TUY|rcsb pdb:5V9I|rcsb pdb:5VSC|rcsb pdb:5VSE|rcsb pdb:6MM1|rcsb pdb:7BTV|rcsb pdb:7BUC|rcsb pdb:7DCF|reactome:R-HSA-2559582|reactome:R-HSA-3214841|reactome:R-HSA-427389|reactome:R-HSA-6804760|reactome:R-HSA-73762|reactome:R-HSA-8853884|reactome:R-HSA-8953750|ensembl:ENSG00000204371(gene)|ensembl:ENSG00000206376(gene)|ensembl:ENSG00000227333(gene)|ensembl:ENSG00000232045(gene)|go:"GO:0010424"(DNA methylation on cytosine within a CG sequence)|go:"GO:0016279"(protein-lysine N-methyltransferase activity)|go:"GO:0016571"(histone methylation)|go:"GO:0016607"(nuclear speck)|go:"GO:0018024"(histone-lysine N-methyltransferase activity)|go:"GO:0018027"(peptidyl-lysine dimethylation)|go:"GO:0034968"(histone lysine methylation)|go:"GO:0035265"(organ growth)|go:"GO:0035690"|go:"GO:0036166"(phenotypic switching)|go:"GO:0044030"(regulation of DNA methylation)|go:"GO:0045471"(response to ethanol)|ensembl:ENSG00000236759(gene)|ensembl:ENSG00000238134(gene)|ensembl:ENST00000375537(transcript)|ensembl:ENST00000383373(transcript)|ensembl:ENST00000420336(transcript)|ensembl:ENST00000421926(transcript)|ensembl:ENST00000429506(transcript)|ensembl:ENST00000450075(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0001222"(transcription corepressor binding)|go:"GO:0002039"(p53 binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006275"(regulation of DNA replication)|go:"GO:0006306"(DNA methylation)|go:"GO:0007130"(synaptonemal complex assembly)|go:"GO:0007286"(spermatid development)|go:"GO:0007616"(long-term memory)|go:"GO:0008270"(zinc ion binding)|go:"GO:0009267"(cellular response to starvation)|go:"GO:0009566"(fertilization)|go:"GO:0046974"("histone methyltransferase activity (H3-K9 specific)")|go:"GO:0046976"("histone methyltransferase activity (H3-K27 specific)")|go:"GO:0048148"(behavioral response to cocaine)|go:"GO:0048665"(neuron fate specification)|go:"GO:0051569"(regulation of histone H3-K4 methylation)|go:"GO:0051570"(regulation of histone H3-K9 methylation)|go:"GO:0060992"(response to fungicide)|go:"GO:0070742"(C2H2 zinc finger domain binding)|go:"GO:0071314"(cellular response to cocaine)|go:"GO:1902902"(negative regulation of autophagosome assembly)|go:"GO:1990841"(promoter-specific chromatin binding)|interpro:IPR001214(SET)|interpro:IPR002110(Ankyrin)|interpro:IPR007728(Pre-SET zinc-binding region)|interpro:IPR020683|interpro:IPR036770|interpro:IPR038034|refseq:NP_001305762.1|refseq:NP_001276342.1|dip:DIP-34461N go:"GO:0005634"(nucleus) - - figure legend:ST3 F2C|comment:proteins that were enriched in the induced sample more than 6-fold|dataset:Brain Disease - Neurological Diseases & Disorders|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-daoy)|taxid:9606(Homo sapiens DAOY cerebellar medulloblastoma cell line) - 2020/12/29 2020/12/29 rogid:cn8gYfKDpQc8J2ygnqny32sIyyU9606 rogid:dblr0h0KBVa6kvaDHhnynRuHE6E9606 rigid:Cnhili6Os5i+9KsmWx3iqclZGC0 false tandem tag:n-n - - - psi-mi:"MI:0658"(multidimensional protein identification technology) psi-mi:"MI:0658"(multidimensional protein identification technology) uniprotkb:P48431 uniprotkb:O76094 intact:EBI-6124081|uniprotkb:Q14537|ensembl:ENSP00000323588 intact:EBI-1058850|ensembl:ENSP00000495128|intact:EBI-2654733|uniprotkb:G5E9Z8|uniprotkb:Q7Z3C0 psi-mi:sox2_human(display_long)|uniprotkb:SOX2(gene name)|psi-mi:SOX2(display_short) psi-mi:srp72_human(display_long)|uniprotkb:SRP72(gene name)|psi-mi:SRP72(display_short)|uniprotkb:Signal recognition particle 72 kDa protein(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Cox et al. (2012) pubmed:23667531|imex:IM-28599 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-26574478|imex:IM-28599-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_003097.1|dip:DIP-59913N|ensembl:ENSG00000181449(gene)|ensembl:ENST00000325404(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001649"(osteoblast differentiation)|go:"GO:0001654"(eye development)|go:"GO:0001714"(endodermal cell fate specification)|go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006325"(chromatin organization)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0009611"(response to wounding)|go:"GO:0009653"(anatomical structure morphogenesis)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0021781"(glial cell fate commitment)|go:"GO:0021983"(pituitary gland development)|go:"GO:0021984"(adenohypophysis development)|go:"GO:0022409"(positive regulation of cell-cell adhesion)|go:"GO:0030154"(cell differentiation)|go:"GO:0030900"(forebrain development)|go:"GO:0035019"(somatic stem cell population maintenance)|go:"GO:0035198"(miRNA binding)|go:"GO:0042246"(tissue regeneration)|go:"GO:0043281"(regulation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0043410"(positive regulation of MAPK cascade)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045165"(cell fate commitment)|go:"GO:0045597"(positive regulation of cell differentiation)|go:"GO:0045665"(negative regulation of neuron differentiation)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048839"(inner ear development)|go:"GO:0050680"(negative regulation of epithelial cell proliferation)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0070848"(response to growth factor)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:0097150"(neuronal stem cell population maintenance)|interpro:IPR009071(High mobility group box, HMG)|interpro:IPR022097|interpro:IPR032643|interpro:IPR036910|mint:P48431|rcsb pdb:1O4X|rcsb pdb:2LE4|rcsb pdb:6T7B|rcsb pdb:6T90|rcsb pdb:6WX7|rcsb pdb:6WX8|rcsb pdb:6WX9|rcsb pdb:6YOV|reactome:R-HSA-2892245|reactome:R-HSA-2892247|reactome:R-HSA-3769402|reactome:R-HSA-452723|reactome:R-HSA-6785807|reactome:R-HSA-8986944 refseq:NP_008878.3|refseq:NP_001254651.1|ensembl:ENSG00000174780(gene)|ensembl:ENST00000642900(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0005047"(signal recognition particle binding)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005786"(signal recognition particle, endoplasmic reticulum targeting)|go:"GO:0005829"(cytosol)|go:"GO:0006614"(SRP-dependent cotranslational protein targeting to membrane)|go:"GO:0008312"(7S RNA binding)|go:"GO:0030911"(TPR domain binding)|go:"GO:0048500"(signal recognition particle)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR013699(Signal recognition particle, SRP72 subunit, RNA-binding)|interpro:IPR019734|interpro:IPR026270|interpro:IPR031545|mint:O76094|rcsb pdb:5M72|rcsb pdb:5M73|rcsb pdb:5WRV|rcsb pdb:5WRW|rcsb pdb:7NFX|reactome:R-HSA-1799339 go:"GO:0005634"(nucleus) - - figure legend:ST3 F2C|comment:proteins that were enriched in the induced sample more than 6-fold|dataset:Brain Disease - Neurological Diseases & Disorders|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-daoy)|taxid:9606(Homo sapiens DAOY cerebellar medulloblastoma cell line) - 2020/12/29 2020/12/29 rogid:cn8gYfKDpQc8J2ygnqny32sIyyU9606 rogid:NJfyOcmKiBWszQsH0EQotsdwhU09606 rigid:Cnhili6Os5i+9KsmWx3iqclZGC0 false tandem tag:n-n - - - psi-mi:"MI:0658"(multidimensional protein identification technology) psi-mi:"MI:0658"(multidimensional protein identification technology) uniprotkb:P48431 uniprotkb:Q9H4L4 intact:EBI-6124081|uniprotkb:Q14537|ensembl:ENSP00000323588 intact:EBI-2880236|ensembl:ENSP00000314029|ensembl:ENSP00000403712|uniprotkb:Q96PS4|uniprotkb:Q66K15|uniprotkb:Q86VS7|uniprotkb:Q9Y3W9 psi-mi:sox2_human(display_long)|uniprotkb:SOX2(gene name)|psi-mi:SOX2(display_short) psi-mi:senp3_human(display_long)|uniprotkb:SENP3(gene name)|psi-mi:SENP3(display_short)|uniprotkb:SSP3(gene name synonym)|uniprotkb:SUSP3(gene name synonym)|uniprotkb:SUMO-1-specific protease 3(gene name synonym)|uniprotkb:Sentrin/SUMO-specific protease SENP3(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Cox et al. (2012) pubmed:23667531|imex:IM-28599 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-26574478|imex:IM-28599-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_003097.1|dip:DIP-59913N|ensembl:ENSG00000181449(gene)|ensembl:ENST00000325404(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001649"(osteoblast differentiation)|go:"GO:0001654"(eye development)|go:"GO:0001714"(endodermal cell fate specification)|go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006325"(chromatin organization)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0009611"(response to wounding)|go:"GO:0009653"(anatomical structure morphogenesis)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0021781"(glial cell fate commitment)|go:"GO:0021983"(pituitary gland development)|go:"GO:0021984"(adenohypophysis development)|go:"GO:0022409"(positive regulation of cell-cell adhesion)|go:"GO:0030154"(cell differentiation)|go:"GO:0030900"(forebrain development)|go:"GO:0035019"(somatic stem cell population maintenance)|go:"GO:0035198"(miRNA binding)|go:"GO:0042246"(tissue regeneration)|go:"GO:0043281"(regulation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0043410"(positive regulation of MAPK cascade)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045165"(cell fate commitment)|go:"GO:0045597"(positive regulation of cell differentiation)|go:"GO:0045665"(negative regulation of neuron differentiation)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048839"(inner ear development)|go:"GO:0050680"(negative regulation of epithelial cell proliferation)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0070848"(response to growth factor)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:0097150"(neuronal stem cell population maintenance)|interpro:IPR009071(High mobility group box, HMG)|interpro:IPR022097|interpro:IPR032643|interpro:IPR036910|mint:P48431|rcsb pdb:1O4X|rcsb pdb:2LE4|rcsb pdb:6T7B|rcsb pdb:6T90|rcsb pdb:6WX7|rcsb pdb:6WX8|rcsb pdb:6WX9|rcsb pdb:6YOV|reactome:R-HSA-2892245|reactome:R-HSA-2892247|reactome:R-HSA-3769402|reactome:R-HSA-452723|reactome:R-HSA-6785807|reactome:R-HSA-8986944 ensembl:ENSG00000161956(gene)|ensembl:ENST00000321337(transcript)|ensembl:ENST00000429205(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0008234"(cysteine-type peptidase activity)|go:"GO:0016926"(protein desumoylation)|go:"GO:0071339"(MLL1 complex)|interpro:IPR003653(Peptidase C48, SUMO/Sentrin/Ubl1)|interpro:IPR037945|interpro:IPR038765|mint:Q9H4L4|reactome:R-HSA-6791226|refseq:NP_056485.2|dip:DIP-47511N go:"GO:0005634"(nucleus) - - figure legend:ST3 F2C|comment:proteins that were enriched in the induced sample more than 6-fold|dataset:Brain Disease - Neurological Diseases & Disorders|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-daoy)|taxid:9606(Homo sapiens DAOY cerebellar medulloblastoma cell line) - 2020/12/29 2020/12/29 rogid:cn8gYfKDpQc8J2ygnqny32sIyyU9606 rogid:sE4k87ORoxSjBkbccPsXLYzuqII9606 rigid:Cnhili6Os5i+9KsmWx3iqclZGC0 false tandem tag:n-n - - - psi-mi:"MI:0658"(multidimensional protein identification technology) psi-mi:"MI:0658"(multidimensional protein identification technology) uniprotkb:P48431 uniprotkb:O00148 intact:EBI-6124081|uniprotkb:Q14537|ensembl:ENSP00000323588 intact:EBI-348253|ensembl:ENSP00000242776|uniprotkb:Q9BVP6|uniprotkb:Q9H5W0|intact:EBI-2514455|uniprotkb:Q8N5M0|uniprotkb:B1Q2N1 psi-mi:sox2_human(display_long)|uniprotkb:SOX2(gene name)|psi-mi:SOX2(display_short) psi-mi:dx39a_human(display_long)|uniprotkb:DEAD box protein 39(gene name synonym)|uniprotkb:Nuclear RNA helicase URH49(gene name synonym)|uniprotkb:DDX39A(gene name)|psi-mi:DDX39A(display_short)|uniprotkb:DDX39(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Cox et al. (2012) pubmed:23667531|imex:IM-28599 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-26574478|imex:IM-28599-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_003097.1|dip:DIP-59913N|ensembl:ENSG00000181449(gene)|ensembl:ENST00000325404(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001649"(osteoblast differentiation)|go:"GO:0001654"(eye development)|go:"GO:0001714"(endodermal cell fate specification)|go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006325"(chromatin organization)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0009611"(response to wounding)|go:"GO:0009653"(anatomical structure morphogenesis)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0021781"(glial cell fate commitment)|go:"GO:0021983"(pituitary gland development)|go:"GO:0021984"(adenohypophysis development)|go:"GO:0022409"(positive regulation of cell-cell adhesion)|go:"GO:0030154"(cell differentiation)|go:"GO:0030900"(forebrain development)|go:"GO:0035019"(somatic stem cell population maintenance)|go:"GO:0035198"(miRNA binding)|go:"GO:0042246"(tissue regeneration)|go:"GO:0043281"(regulation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0043410"(positive regulation of MAPK cascade)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045165"(cell fate commitment)|go:"GO:0045597"(positive regulation of cell differentiation)|go:"GO:0045665"(negative regulation of neuron differentiation)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048839"(inner ear development)|go:"GO:0050680"(negative regulation of epithelial cell proliferation)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0070848"(response to growth factor)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:0097150"(neuronal stem cell population maintenance)|interpro:IPR009071(High mobility group box, HMG)|interpro:IPR022097|interpro:IPR032643|interpro:IPR036910|mint:P48431|rcsb pdb:1O4X|rcsb pdb:2LE4|rcsb pdb:6T7B|rcsb pdb:6T90|rcsb pdb:6WX7|rcsb pdb:6WX8|rcsb pdb:6WX9|rcsb pdb:6YOV|reactome:R-HSA-2892245|reactome:R-HSA-2892247|reactome:R-HSA-3769402|reactome:R-HSA-452723|reactome:R-HSA-6785807|reactome:R-HSA-8986944 ensembl:ENSG00000123136(gene)|ensembl:ENST00000242776(transcript)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0003723"(RNA binding)|go:"GO:0003724"(RNA helicase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006405"(RNA export from nucleus)|go:"GO:0006406"(mRNA export from nucleus)|go:"GO:0016020"(membrane)|go:"GO:0016607"(nuclear speck)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR011545(DNA/RNA helicase, DEAD/DEAH box type, N-terminal)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR014014(RNA helicase, DEAD-box type, Q motif)|interpro:IPR027417|mint:O00148|reactome:R-HSA-159236|reactome:R-HSA-72187|reactome:R-HSA-73856|go:"GO:0042802"(identical protein binding)|refseq:NP_005795.2|refseq:XP_011525922.1 go:"GO:0005634"(nucleus) - - figure legend:ST3 F2C|comment:proteins that were enriched in the induced sample more than 6-fold|dataset:Brain Disease - Neurological Diseases & Disorders|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-daoy)|taxid:9606(Homo sapiens DAOY cerebellar medulloblastoma cell line) - 2020/12/29 2020/12/29 rogid:cn8gYfKDpQc8J2ygnqny32sIyyU9606 rogid:EOc5EPfkNVMrdfd9Xx/snoOfhas9606 rigid:Cnhili6Os5i+9KsmWx3iqclZGC0 false tandem tag:n-n - - - psi-mi:"MI:0658"(multidimensional protein identification technology) psi-mi:"MI:0658"(multidimensional protein identification technology) uniprotkb:P48431 uniprotkb:O60716 intact:EBI-6124081|uniprotkb:Q14537|ensembl:ENSP00000323588 intact:EBI-701927|uniprotkb:A8K939|uniprotkb:Q6DHZ7|uniprotkb:O15088|uniprotkb:O60713|uniprotkb:O60714|uniprotkb:O60715|uniprotkb:O60935|uniprotkb:Q6RBX8|uniprotkb:Q9UP71|uniprotkb:Q9UP72|uniprotkb:Q9UP73|ensembl:ENSP00000382004 psi-mi:sox2_human(display_long)|uniprotkb:SOX2(gene name)|psi-mi:SOX2(display_short) psi-mi:ctnd1_human(display_long)|uniprotkb:p120 catenin(gene name synonym)|uniprotkb:Cadherin-associated Src substrate(gene name synonym)|uniprotkb:"p120(cas)"(gene name synonym)|uniprotkb:CTNND1(gene name)|psi-mi:CTNND1(display_short)|uniprotkb:KIAA0384(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Cox et al. (2012) pubmed:23667531|imex:IM-28599 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-26574478|imex:IM-28599-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_003097.1|dip:DIP-59913N|ensembl:ENSG00000181449(gene)|ensembl:ENST00000325404(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001649"(osteoblast differentiation)|go:"GO:0001654"(eye development)|go:"GO:0001714"(endodermal cell fate specification)|go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006325"(chromatin organization)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0009611"(response to wounding)|go:"GO:0009653"(anatomical structure morphogenesis)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0021781"(glial cell fate commitment)|go:"GO:0021983"(pituitary gland development)|go:"GO:0021984"(adenohypophysis development)|go:"GO:0022409"(positive regulation of cell-cell adhesion)|go:"GO:0030154"(cell differentiation)|go:"GO:0030900"(forebrain development)|go:"GO:0035019"(somatic stem cell population maintenance)|go:"GO:0035198"(miRNA binding)|go:"GO:0042246"(tissue regeneration)|go:"GO:0043281"(regulation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0043410"(positive regulation of MAPK cascade)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045165"(cell fate commitment)|go:"GO:0045597"(positive regulation of cell differentiation)|go:"GO:0045665"(negative regulation of neuron differentiation)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048839"(inner ear development)|go:"GO:0050680"(negative regulation of epithelial cell proliferation)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0070848"(response to growth factor)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:0097150"(neuronal stem cell population maintenance)|interpro:IPR009071(High mobility group box, HMG)|interpro:IPR022097|interpro:IPR032643|interpro:IPR036910|mint:P48431|rcsb pdb:1O4X|rcsb pdb:2LE4|rcsb pdb:6T7B|rcsb pdb:6T90|rcsb pdb:6WX7|rcsb pdb:6WX8|rcsb pdb:6WX9|rcsb pdb:6YOV|reactome:R-HSA-2892245|reactome:R-HSA-2892247|reactome:R-HSA-3769402|reactome:R-HSA-452723|reactome:R-HSA-6785807|reactome:R-HSA-8986944 refseq:NP_001078927.1|refseq:NP_001078928.1|refseq:NP_001078929.1|refseq:NP_001078930.1|refseq:NP_001078931.1|refseq:NP_001078932.1|refseq:NP_001078933.1|refseq:NP_001078934.1|refseq:NP_001078935.1|refseq:NP_001078936.1|refseq:NP_001078937.1|refseq:NP_001078938.1|refseq:NP_001193812.1|refseq:NP_001193813.1|refseq:NP_001193814.1|refseq:NP_001193815.1|refseq:NP_001193816.1|refseq:NP_001193817.1|refseq:NP_001193818.1|refseq:NP_001193819.1|refseq:NP_001193820.1|refseq:NP_001322.1|dip:DIP-33850N|ensembl:ENSG00000198561(gene)|ensembl:ENST00000399050(transcript)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005912"(adherens junction)|go:"GO:0005915"(zonula adherens)|go:"GO:0007043"(cell-cell junction assembly)|go:"GO:0007420"(brain development)|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0016342"(catenin complex)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030027"(lamellipodium)|go:"GO:0030426"(growth cone)|go:"GO:0030496"(midbody)|go:"GO:0043197"(dendritic spine)|go:"GO:0044331"(cell-cell adhesion mediated by cadherin)|go:"GO:0045296"(cadherin binding)|go:"GO:0050821"(protein stabilization)|go:"GO:0070062"(extracellular exosome)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:0098609"(cell-cell adhesion)|go:"GO:0098685"(Schaffer collateral - CA1 synapse)|go:"GO:0098686"(hippocampal mossy fiber to CA3 synapse)|go:"GO:0098831"(presynaptic active zone cytoplasmic component)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099072"(regulation of postsynaptic membrane neurotransmitter receptor levels)|go:"GO:0099092"(postsynaptic density, intracellular component)|interpro:IPR000225(Armadillo)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR028435|interpro:IPR028439|mint:O60716|rcsb pdb:3L6X|rcsb pdb:3L6Y|reactome:R-HSA-418990|reactome:R-HSA-5218920|reactome:R-HSA-8876493 go:"GO:0005634"(nucleus) - - figure legend:ST3 F2C|comment:proteins that were enriched in the induced sample more than 6-fold|dataset:Brain Disease - Neurological Diseases & Disorders|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-daoy)|taxid:9606(Homo sapiens DAOY cerebellar medulloblastoma cell line) - 2020/12/29 2020/12/29 rogid:cn8gYfKDpQc8J2ygnqny32sIyyU9606 rogid:HgMvbcDKedE291TIvIOqLFT3srw9606 rigid:Cnhili6Os5i+9KsmWx3iqclZGC0 false tandem tag:n-n - - - psi-mi:"MI:0658"(multidimensional protein identification technology) psi-mi:"MI:0658"(multidimensional protein identification technology) uniprotkb:P48431 uniprotkb:Q8IX01 intact:EBI-6124081|uniprotkb:Q14537|ensembl:ENSP00000323588 intact:EBI-949116|ensembl:ENSP00000337926|ensembl:ENSP00000389380|ensembl:ENSP00000472286|uniprotkb:O15071|uniprotkb:O60369|uniprotkb:Q5JPH7|uniprotkb:Q8WUF7|uniprotkb:C9JI71 psi-mi:sox2_human(display_long)|uniprotkb:SOX2(gene name)|psi-mi:SOX2(display_short) psi-mi:sugp2_human(display_long)|uniprotkb:Arginine/serine-rich-splicing factor 14(gene name synonym)|uniprotkb:SUGP2(gene name)|psi-mi:SUGP2(display_short)|uniprotkb:KIAA0365(gene name synonym)|uniprotkb:SFRS14(gene name synonym)|uniprotkb:Splicing factor, arginine/serine-rich 14(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Cox et al. (2012) pubmed:23667531|imex:IM-28599 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-26574478|imex:IM-28599-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_003097.1|dip:DIP-59913N|ensembl:ENSG00000181449(gene)|ensembl:ENST00000325404(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001649"(osteoblast differentiation)|go:"GO:0001654"(eye development)|go:"GO:0001714"(endodermal cell fate specification)|go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006325"(chromatin organization)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0009611"(response to wounding)|go:"GO:0009653"(anatomical structure morphogenesis)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0021781"(glial cell fate commitment)|go:"GO:0021983"(pituitary gland development)|go:"GO:0021984"(adenohypophysis development)|go:"GO:0022409"(positive regulation of cell-cell adhesion)|go:"GO:0030154"(cell differentiation)|go:"GO:0030900"(forebrain development)|go:"GO:0035019"(somatic stem cell population maintenance)|go:"GO:0035198"(miRNA binding)|go:"GO:0042246"(tissue regeneration)|go:"GO:0043281"(regulation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0043410"(positive regulation of MAPK cascade)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045165"(cell fate commitment)|go:"GO:0045597"(positive regulation of cell differentiation)|go:"GO:0045665"(negative regulation of neuron differentiation)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048839"(inner ear development)|go:"GO:0050680"(negative regulation of epithelial cell proliferation)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0070848"(response to growth factor)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:0097150"(neuronal stem cell population maintenance)|interpro:IPR009071(High mobility group box, HMG)|interpro:IPR022097|interpro:IPR032643|interpro:IPR036910|mint:P48431|rcsb pdb:1O4X|rcsb pdb:2LE4|rcsb pdb:6T7B|rcsb pdb:6T90|rcsb pdb:6WX7|rcsb pdb:6WX8|rcsb pdb:6WX9|rcsb pdb:6YOV|reactome:R-HSA-2892245|reactome:R-HSA-2892247|reactome:R-HSA-3769402|reactome:R-HSA-452723|reactome:R-HSA-6785807|reactome:R-HSA-8986944 ensembl:ENSG00000064607(gene)|ensembl:ENST00000337018(transcript)|ensembl:ENST00000452918(transcript)|ensembl:ENST00000601879(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006397"(mRNA processing)|go:"GO:0008380"(RNA splicing)|go:"GO:0016604"(nuclear body)|interpro:IPR000061(SWAP/Surp)|interpro:IPR000467(D111/G-patch)|interpro:IPR035967|interpro:IPR040169|mint:Q8IX01|rcsb pdb:1X4P|refseq:NP_001017392.2|refseq:NP_055699.2|refseq:XP_016881626.1|refseq:NP_001308626.1 go:"GO:0005634"(nucleus) - - figure legend:ST3 F2C|comment:proteins that were enriched in the induced sample more than 6-fold|dataset:Brain Disease - Neurological Diseases & Disorders|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-daoy)|taxid:9606(Homo sapiens DAOY cerebellar medulloblastoma cell line) - 2020/12/29 2020/12/29 rogid:cn8gYfKDpQc8J2ygnqny32sIyyU9606 rogid:hN1zWaoMMufKCQNO9VQ8NPiN0hI9606 rigid:Cnhili6Os5i+9KsmWx3iqclZGC0 false tandem tag:n-n - - - psi-mi:"MI:0658"(multidimensional protein identification technology) psi-mi:"MI:0658"(multidimensional protein identification technology) uniprotkb:P48431 uniprotkb:O00410 intact:EBI-6124081|uniprotkb:Q14537|ensembl:ENSP00000323588 intact:EBI-356424|uniprotkb:O15257|intact:EBI-1105173|uniprotkb:B4DZA0|uniprotkb:Q5T578|uniprotkb:Q86XC7|ensembl:ENSP00000350219|ensembl:ENSP00000418393|ensembl:ENSP00000499125 psi-mi:sox2_human(display_long)|uniprotkb:SOX2(gene name)|psi-mi:SOX2(display_short) psi-mi:ipo5_human(display_long)|uniprotkb:IPO5(gene name)|psi-mi:IPO5(display_short)|uniprotkb:KPNB3(gene name synonym)|uniprotkb:RANBP5(gene name synonym)|uniprotkb:Importin subunit beta-3(gene name synonym)|uniprotkb:Karyopherin beta-3(gene name synonym)|uniprotkb:Ran-binding protein 5(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Cox et al. (2012) pubmed:23667531|imex:IM-28599 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-26574478|imex:IM-28599-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_003097.1|dip:DIP-59913N|ensembl:ENSG00000181449(gene)|ensembl:ENST00000325404(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001649"(osteoblast differentiation)|go:"GO:0001654"(eye development)|go:"GO:0001714"(endodermal cell fate specification)|go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006325"(chromatin organization)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0009611"(response to wounding)|go:"GO:0009653"(anatomical structure morphogenesis)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0021781"(glial cell fate commitment)|go:"GO:0021983"(pituitary gland development)|go:"GO:0021984"(adenohypophysis development)|go:"GO:0022409"(positive regulation of cell-cell adhesion)|go:"GO:0030154"(cell differentiation)|go:"GO:0030900"(forebrain development)|go:"GO:0035019"(somatic stem cell population maintenance)|go:"GO:0035198"(miRNA binding)|go:"GO:0042246"(tissue regeneration)|go:"GO:0043281"(regulation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0043410"(positive regulation of MAPK cascade)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045165"(cell fate commitment)|go:"GO:0045597"(positive regulation of cell differentiation)|go:"GO:0045665"(negative regulation of neuron differentiation)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048839"(inner ear development)|go:"GO:0050680"(negative regulation of epithelial cell proliferation)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0070848"(response to growth factor)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:0097150"(neuronal stem cell population maintenance)|interpro:IPR009071(High mobility group box, HMG)|interpro:IPR022097|interpro:IPR032643|interpro:IPR036910|mint:P48431|rcsb pdb:1O4X|rcsb pdb:2LE4|rcsb pdb:6T7B|rcsb pdb:6T90|rcsb pdb:6WX7|rcsb pdb:6WX8|rcsb pdb:6WX9|rcsb pdb:6YOV|reactome:R-HSA-2892245|reactome:R-HSA-2892247|reactome:R-HSA-3769402|reactome:R-HSA-452723|reactome:R-HSA-6785807|reactome:R-HSA-8986944 refseq:NP_002262.3|refseq:XP_011519389.1|refseq:XP_011519390.1|refseq:XP_011519391.1|refseq:XP_011519392.1|ensembl:ENSG00000065150(gene)|ensembl:ENST00000357602(transcript)|ensembl:ENST00000490680(transcript)|ensembl:ENST00000651721(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0005095"(GTPase inhibitor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005643"(nuclear pore)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0006607"(NLS-bearing protein import into nucleus)|go:"GO:0006610"(ribosomal protein import into nucleus)|go:"GO:0008139"(nuclear localization sequence binding)|refseq:XP_005254109.1|refseq:XP_005254110.1|go:"GO:0016020"(membrane)|go:"GO:0031267"(small GTPase binding)|go:"GO:0042307"(positive regulation of protein import into nucleus)|go:"GO:0045736"(negative regulation of cyclin-dependent protein serine/threonine kinase activity)|go:"GO:0061608"(nuclear import signal receptor activity)|go:"GO:0071230"(cellular response to amino acid stimulus)|interpro:IPR000357(HEAT)|interpro:IPR001494(Importin-beta, N-terminal)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR034085|interpro:IPR040122|interpro:IPR040928|interpro:IPR041389|interpro:IPR041653|mint:O00410|rcsb pdb:6XTE|rcsb pdb:6XU2|reactome:R-HSA-192905|refseq:XP_016876051.1|dip:DIP-41042N go:"GO:0005634"(nucleus) - - figure legend:ST3 F2C|comment:proteins that were enriched in the induced sample more than 6-fold|dataset:Brain Disease - Neurological Diseases & Disorders|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-daoy)|taxid:9606(Homo sapiens DAOY cerebellar medulloblastoma cell line) - 2020/12/29 2020/12/29 rogid:cn8gYfKDpQc8J2ygnqny32sIyyU9606 rogid:jBYLvkqyYyWAu1TdCVyCMh9ZHKY9606 rigid:Cnhili6Os5i+9KsmWx3iqclZGC0 false tandem tag:n-n - - - psi-mi:"MI:0658"(multidimensional protein identification technology) psi-mi:"MI:0658"(multidimensional protein identification technology) uniprotkb:P48431 uniprotkb:O00629 intact:EBI-6124081|uniprotkb:Q14537|ensembl:ENSP00000323588 intact:EBI-396343|uniprotkb:O00190|intact:EBI-28976443|ensembl:ENSP00000334373|uniprotkb:A8K4S6|uniprotkb:D3DNM2 psi-mi:sox2_human(display_long)|uniprotkb:SOX2(gene name)|psi-mi:SOX2(display_short) psi-mi:ima3_human(display_long)|uniprotkb:KPNA4(gene name)|psi-mi:KPNA4(display_short)|uniprotkb:QIP1(gene name synonym)|uniprotkb:Karyopherin subunit alpha-4(gene name synonym)|uniprotkb:Importin alpha Q1(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Cox et al. (2012) pubmed:23667531|imex:IM-28599 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-26574478|imex:IM-28599-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_003097.1|dip:DIP-59913N|ensembl:ENSG00000181449(gene)|ensembl:ENST00000325404(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001649"(osteoblast differentiation)|go:"GO:0001654"(eye development)|go:"GO:0001714"(endodermal cell fate specification)|go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006325"(chromatin organization)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0009611"(response to wounding)|go:"GO:0009653"(anatomical structure morphogenesis)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0021781"(glial cell fate commitment)|go:"GO:0021983"(pituitary gland development)|go:"GO:0021984"(adenohypophysis development)|go:"GO:0022409"(positive regulation of cell-cell adhesion)|go:"GO:0030154"(cell differentiation)|go:"GO:0030900"(forebrain development)|go:"GO:0035019"(somatic stem cell population maintenance)|go:"GO:0035198"(miRNA binding)|go:"GO:0042246"(tissue regeneration)|go:"GO:0043281"(regulation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0043410"(positive regulation of MAPK cascade)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045165"(cell fate commitment)|go:"GO:0045597"(positive regulation of cell differentiation)|go:"GO:0045665"(negative regulation of neuron differentiation)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048839"(inner ear development)|go:"GO:0050680"(negative regulation of epithelial cell proliferation)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0070848"(response to growth factor)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:0097150"(neuronal stem cell population maintenance)|interpro:IPR009071(High mobility group box, HMG)|interpro:IPR022097|interpro:IPR032643|interpro:IPR036910|mint:P48431|rcsb pdb:1O4X|rcsb pdb:2LE4|rcsb pdb:6T7B|rcsb pdb:6T90|rcsb pdb:6WX7|rcsb pdb:6WX8|rcsb pdb:6WX9|rcsb pdb:6YOV|reactome:R-HSA-2892245|reactome:R-HSA-2892247|reactome:R-HSA-3769402|reactome:R-HSA-452723|reactome:R-HSA-6785807|reactome:R-HSA-8986944 refseq:NP_002259.1|ensembl:ENSG00000186432(gene)|ensembl:ENST00000334256(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006607"(NLS-bearing protein import into nucleus)|go:"GO:0008139"(nuclear localization sequence binding)|go:"GO:0031965"(nuclear membrane)|go:"GO:0061608"(nuclear import signal receptor activity)|interpro:IPR000225(Armadillo)|interpro:IPR002652(Importin-alpha-like, importin-beta-binding region)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR024931|interpro:IPR032413|interpro:IPR036975|mint:O00629|rcsb pdb:4UAE|rcsb pdb:5TBK|rcsb pdb:5XZX|rcsb pdb:6BVV|rcsb pdb:6BVZ|rcsb pdb:6BW9|rcsb pdb:6BWA|rcsb pdb:6BWB|rcsb pdb:6WX8|rcsb pdb:7JJL|reactome:R-HSA-1169408|reactome:R-HSA-168276|ensembl:ENSP00000334373|dip:DIP-32982N go:"GO:0005634"(nucleus) - - figure legend:ST3 F2C|comment:proteins that were enriched in the induced sample more than 6-fold|dataset:Brain Disease - Neurological Diseases & Disorders|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-daoy)|taxid:9606(Homo sapiens DAOY cerebellar medulloblastoma cell line) - 2020/12/29 2020/12/29 rogid:cn8gYfKDpQc8J2ygnqny32sIyyU9606 rogid:/cng/xZ42E2juzHNOpuQTP+amx89606 rigid:Cnhili6Os5i+9KsmWx3iqclZGC0 false tandem tag:n-n - - - psi-mi:"MI:0658"(multidimensional protein identification technology) psi-mi:"MI:0658"(multidimensional protein identification technology) uniprotkb:P48431 uniprotkb:Q8TEX9 intact:EBI-6124081|uniprotkb:Q14537|ensembl:ENSP00000323588 intact:EBI-395967|uniprotkb:Q2NL96|uniprotkb:Q86TZ9|uniprotkb:Q8NCG8|uniprotkb:Q96SJ3|uniprotkb:Q9BTI4|uniprotkb:Q9H5L0|uniprotkb:B2RN95|ensembl:ENSP00000346453|ensembl:ENSP00000494795 psi-mi:sox2_human(display_long)|uniprotkb:SOX2(gene name)|psi-mi:SOX2(display_short) psi-mi:ipo4_human(display_long)|uniprotkb:IPO4(gene name)|psi-mi:IPO4(display_short)|uniprotkb:IMP4B(gene name synonym)|uniprotkb:RANBP4(gene name synonym)|uniprotkb:Importin-4b(gene name synonym)|uniprotkb:Ran-binding protein 4(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Cox et al. (2012) pubmed:23667531|imex:IM-28599 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-26574478|imex:IM-28599-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_003097.1|dip:DIP-59913N|ensembl:ENSG00000181449(gene)|ensembl:ENST00000325404(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001649"(osteoblast differentiation)|go:"GO:0001654"(eye development)|go:"GO:0001714"(endodermal cell fate specification)|go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006325"(chromatin organization)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0009611"(response to wounding)|go:"GO:0009653"(anatomical structure morphogenesis)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0021781"(glial cell fate commitment)|go:"GO:0021983"(pituitary gland development)|go:"GO:0021984"(adenohypophysis development)|go:"GO:0022409"(positive regulation of cell-cell adhesion)|go:"GO:0030154"(cell differentiation)|go:"GO:0030900"(forebrain development)|go:"GO:0035019"(somatic stem cell population maintenance)|go:"GO:0035198"(miRNA binding)|go:"GO:0042246"(tissue regeneration)|go:"GO:0043281"(regulation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0043410"(positive regulation of MAPK cascade)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045165"(cell fate commitment)|go:"GO:0045597"(positive regulation of cell differentiation)|go:"GO:0045665"(negative regulation of neuron differentiation)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048839"(inner ear development)|go:"GO:0050680"(negative regulation of epithelial cell proliferation)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0070848"(response to growth factor)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:0097150"(neuronal stem cell population maintenance)|interpro:IPR009071(High mobility group box, HMG)|interpro:IPR022097|interpro:IPR032643|interpro:IPR036910|mint:P48431|rcsb pdb:1O4X|rcsb pdb:2LE4|rcsb pdb:6T7B|rcsb pdb:6T90|rcsb pdb:6WX7|rcsb pdb:6WX8|rcsb pdb:6WX9|rcsb pdb:6YOV|reactome:R-HSA-2892245|reactome:R-HSA-2892247|reactome:R-HSA-3769402|reactome:R-HSA-452723|reactome:R-HSA-6785807|reactome:R-HSA-8986944 refseq:NP_078934.3|dip:DIP-32944N|ensembl:ENSG00000196497(gene)|ensembl:ENSG00000285248(gene)|ensembl:ENST00000354464(transcript)|ensembl:ENST00000644546(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006335"(DNA replication-dependent chromatin assembly)|go:"GO:0006336"(DNA replication-independent chromatin assembly)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0008139"(nuclear localization sequence binding)|go:"GO:0016020"(membrane)|go:"GO:0031267"(small GTPase binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0061608"(nuclear import signal receptor activity)|interpro:IPR000357(HEAT)|interpro:IPR001494(Importin-beta, N-terminal)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR021133|interpro:IPR034085|interpro:IPR040122|mint:Q8TEX9|rcsb pdb:5XAH|rcsb pdb:5XBK go:"GO:0005634"(nucleus) - - figure legend:ST3 F2C|comment:proteins that were enriched in the induced sample more than 6-fold|dataset:Brain Disease - Neurological Diseases & Disorders|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-daoy)|taxid:9606(Homo sapiens DAOY cerebellar medulloblastoma cell line) - 2020/12/29 2020/12/29 rogid:cn8gYfKDpQc8J2ygnqny32sIyyU9606 rogid:PVIcGG3WTf0QmYbS0vvy049EjlQ9606 rigid:Cnhili6Os5i+9KsmWx3iqclZGC0 false tandem tag:n-n - - - psi-mi:"MI:0658"(multidimensional protein identification technology) psi-mi:"MI:0658"(multidimensional protein identification technology) uniprotkb:P48431 uniprotkb:P68366 intact:EBI-6124081|uniprotkb:Q14537|ensembl:ENSP00000323588 intact:EBI-351772|uniprotkb:A8MUB1|uniprotkb:P05215|ensembl:ENSP00000248437|uniprotkb:B3KNQ6|intact:EBI-11134566 psi-mi:sox2_human(display_long)|uniprotkb:SOX2(gene name)|psi-mi:SOX2(display_short) psi-mi:tba4a_human(display_long)|uniprotkb:TUBA4A(gene name)|psi-mi:TUBA4A(display_short)|uniprotkb:Tubulin alpha-1 chain(gene name synonym)|uniprotkb:Alpha-tubulin 1(gene name synonym)|uniprotkb:Testis-specific alpha-tubulin(gene name synonym)|uniprotkb:Tubulin H2-alpha(gene name synonym)|uniprotkb:TUBA1(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Cox et al. (2012) pubmed:23667531|imex:IM-28599 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-26574478|imex:IM-28599-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_003097.1|dip:DIP-59913N|ensembl:ENSG00000181449(gene)|ensembl:ENST00000325404(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001649"(osteoblast differentiation)|go:"GO:0001654"(eye development)|go:"GO:0001714"(endodermal cell fate specification)|go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006325"(chromatin organization)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0009611"(response to wounding)|go:"GO:0009653"(anatomical structure morphogenesis)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0021781"(glial cell fate commitment)|go:"GO:0021983"(pituitary gland development)|go:"GO:0021984"(adenohypophysis development)|go:"GO:0022409"(positive regulation of cell-cell adhesion)|go:"GO:0030154"(cell differentiation)|go:"GO:0030900"(forebrain development)|go:"GO:0035019"(somatic stem cell population maintenance)|go:"GO:0035198"(miRNA binding)|go:"GO:0042246"(tissue regeneration)|go:"GO:0043281"(regulation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0043410"(positive regulation of MAPK cascade)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045165"(cell fate commitment)|go:"GO:0045597"(positive regulation of cell differentiation)|go:"GO:0045665"(negative regulation of neuron differentiation)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048839"(inner ear development)|go:"GO:0050680"(negative regulation of epithelial cell proliferation)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0070848"(response to growth factor)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:0097150"(neuronal stem cell population maintenance)|interpro:IPR009071(High mobility group box, HMG)|interpro:IPR022097|interpro:IPR032643|interpro:IPR036910|mint:P48431|rcsb pdb:1O4X|rcsb pdb:2LE4|rcsb pdb:6T7B|rcsb pdb:6T90|rcsb pdb:6WX7|rcsb pdb:6WX8|rcsb pdb:6WX9|rcsb pdb:6YOV|reactome:R-HSA-2892245|reactome:R-HSA-2892247|reactome:R-HSA-3769402|reactome:R-HSA-452723|reactome:R-HSA-6785807|reactome:R-HSA-8986944 refseq:NP_005991.1|ensembl:ENSG00000127824(gene)|ensembl:ENST00000248437(transcript)|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0005200"(structural constituent of cytoskeleton)|go:"GO:0005525"(GTP binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005874"(microtubule)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0019901"(protein kinase binding)|go:"GO:0070062"(extracellular exosome)|interpro:IPR000217(Tubulin)|interpro:IPR002452(Alpha tubulin)|interpro:IPR003008(Tubulin/FtsZ, GTPase)|interpro:IPR008280(Tubulin/FtsZ, C-terminal)|interpro:IPR017975|interpro:IPR018316|interpro:IPR023123|interpro:IPR036525|interpro:IPR037103|mint:P68366|reactome:R-HSA-114608|reactome:R-HSA-1445148|reactome:R-HSA-190840|reactome:R-HSA-190861|reactome:R-HSA-2132295|reactome:R-HSA-2467813|reactome:R-HSA-2500257|reactome:R-HSA-2565942|reactome:R-HSA-3371497|reactome:R-HSA-380259|reactome:R-HSA-380270|reactome:R-HSA-380284|reactome:R-HSA-380320|reactome:R-HSA-389957|reactome:R-HSA-389960|reactome:R-HSA-389977|reactome:R-HSA-437239|reactome:R-HSA-5610787|reactome:R-HSA-5617833|reactome:R-HSA-5620912|reactome:R-HSA-5620924|reactome:R-HSA-5626467|reactome:R-HSA-5663220|reactome:R-HSA-6807878|reactome:R-HSA-6811434|reactome:R-HSA-6811436|reactome:R-HSA-68877|reactome:R-HSA-8852276|reactome:R-HSA-8854518|reactome:R-HSA-8955332|reactome:R-HSA-9609690|reactome:R-HSA-9609736|reactome:R-HSA-9619483|reactome:R-HSA-9646399|reactome:R-HSA-9648025|reactome:R-HSA-9668328|reactome:R-HSA-983189|refseq:NP_001265481.1 go:"GO:0005634"(nucleus) - - figure legend:ST3 F2C|comment:proteins that were enriched in the induced sample more than 6-fold|dataset:Brain Disease - Neurological Diseases & Disorders|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-daoy)|taxid:9606(Homo sapiens DAOY cerebellar medulloblastoma cell line) - 2020/12/29 2020/12/29 rogid:cn8gYfKDpQc8J2ygnqny32sIyyU9606 rogid:6Oj9O8u7E6cLUJ1eT6y5slbk7uQ9606 rigid:Cnhili6Os5i+9KsmWx3iqclZGC0 false tandem tag:n-n - - - psi-mi:"MI:0658"(multidimensional protein identification technology) psi-mi:"MI:0658"(multidimensional protein identification technology) uniprotkb:P48431 uniprotkb:Q8N163 intact:EBI-6124081|uniprotkb:Q14537|ensembl:ENSP00000323588 intact:EBI-355410|uniprotkb:A6NL03|uniprotkb:Q6P0Q9|uniprotkb:Q8N3G7|uniprotkb:Q8N8M1|uniprotkb:Q8TF34|uniprotkb:Q9H9Q9|uniprotkb:Q9HD12|uniprotkb:Q9NT55|ensembl:ENSP00000310670|ensembl:ENSP00000373930|uniprotkb:B2RB79|uniprotkb:D3DSR6 psi-mi:sox2_human(display_long)|uniprotkb:SOX2(gene name)|psi-mi:SOX2(display_short) psi-mi:ccar2_human(display_long)|uniprotkb:CCAR2(gene name)|psi-mi:CCAR2(display_short)|uniprotkb:Cell division cycle and apoptosis regulator protein 2(gene name synonym)|uniprotkb:DBC1(gene name synonym)|uniprotkb:DBIRD complex subunit KIAA1967(gene name synonym)|uniprotkb:Deleted in breast cancer gene 1 protein(gene name synonym)|uniprotkb:KIAA1967(gene name synonym)|uniprotkb:p30 DBC(gene name synonym)|uniprotkb:NET35(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Cox et al. (2012) pubmed:23667531|imex:IM-28599 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-26574478|imex:IM-28599-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_003097.1|dip:DIP-59913N|ensembl:ENSG00000181449(gene)|ensembl:ENST00000325404(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001649"(osteoblast differentiation)|go:"GO:0001654"(eye development)|go:"GO:0001714"(endodermal cell fate specification)|go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006325"(chromatin organization)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0009611"(response to wounding)|go:"GO:0009653"(anatomical structure morphogenesis)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0021781"(glial cell fate commitment)|go:"GO:0021983"(pituitary gland development)|go:"GO:0021984"(adenohypophysis development)|go:"GO:0022409"(positive regulation of cell-cell adhesion)|go:"GO:0030154"(cell differentiation)|go:"GO:0030900"(forebrain development)|go:"GO:0035019"(somatic stem cell population maintenance)|go:"GO:0035198"(miRNA binding)|go:"GO:0042246"(tissue regeneration)|go:"GO:0043281"(regulation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0043410"(positive regulation of MAPK cascade)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045165"(cell fate commitment)|go:"GO:0045597"(positive regulation of cell differentiation)|go:"GO:0045665"(negative regulation of neuron differentiation)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048839"(inner ear development)|go:"GO:0050680"(negative regulation of epithelial cell proliferation)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0070848"(response to growth factor)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:0097150"(neuronal stem cell population maintenance)|interpro:IPR009071(High mobility group box, HMG)|interpro:IPR022097|interpro:IPR032643|interpro:IPR036910|mint:P48431|rcsb pdb:1O4X|rcsb pdb:2LE4|rcsb pdb:6T7B|rcsb pdb:6T90|rcsb pdb:6WX7|rcsb pdb:6WX8|rcsb pdb:6WX9|rcsb pdb:6YOV|reactome:R-HSA-2892245|reactome:R-HSA-2892247|reactome:R-HSA-3769402|reactome:R-HSA-452723|reactome:R-HSA-6785807|reactome:R-HSA-8986944 refseq:NP_066997.3|ensembl:ENSG00000158941(gene)|ensembl:ENST00000308511(transcript)|ensembl:ENST00000389279(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000993"(RNA polymerase II complex binding)|go:"GO:0003723"(RNA binding)|go:"GO:0004857"(enzyme inhibitor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0005819"(spindle)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006397"(mRNA processing)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0007049"(cell cycle)|go:"GO:0008380"(RNA splicing)|go:"GO:0009411"(response to UV)|go:"GO:0016055"(Wnt signaling pathway)|interpro:IPR028811|mint:Q8N163|reactome:R-HSA-3371453|go:"GO:0019899"(enzyme binding)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0030374"(nuclear receptor coactivator activity)|go:"GO:0031647"(regulation of protein stability)|go:"GO:0032435"(negative regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0032784"(regulation of DNA-templated transcription, elongation)|go:"GO:0042752"(regulation of circadian rhythm)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043086"(negative regulation of catalytic activity)|go:"GO:0043653"(mitochondrial fragmentation involved in apoptotic process)|go:"GO:0044609"(DBIRD complex)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0048511"(rhythmic process)|go:"GO:0090263"(positive regulation of canonical Wnt signaling pathway)|go:"GO:0090311"(regulation of protein deacetylation)|go:"GO:1902230"(negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage)|go:"GO:2000003"(positive regulation of DNA damage checkpoint)|interpro:IPR011992(EF-Hand type)|interpro:IPR025223|interpro:IPR025224|interpro:IPR025954|dip:DIP-38122N go:"GO:0005634"(nucleus) - - figure legend:ST3 F2C|comment:proteins that were enriched in the induced sample more than 6-fold|dataset:Brain Disease - Neurological Diseases & Disorders|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-daoy)|taxid:9606(Homo sapiens DAOY cerebellar medulloblastoma cell line) - 2020/12/29 2020/12/29 rogid:cn8gYfKDpQc8J2ygnqny32sIyyU9606 rogid:GL+fD8W0kadrYrBkuMqoKgbbITU9606 rigid:Cnhili6Os5i+9KsmWx3iqclZGC0 false tandem tag:n-n - - - psi-mi:"MI:0658"(multidimensional protein identification technology) psi-mi:"MI:0658"(multidimensional protein identification technology) uniprotkb:P48431 uniprotkb:Q8IUR7 intact:EBI-6124081|uniprotkb:Q14537|ensembl:ENSP00000323588 intact:EBI-1049469|uniprotkb:Q6PIL2|uniprotkb:Q96D19|uniprotkb:Q96HZ5|uniprotkb:Q9NV02|uniprotkb:Q9NV94|uniprotkb:Q9Y4R9|uniprotkb:A8K0L2|uniprotkb:D3DNE6|uniprotkb:B7Z441|uniprotkb:B7Z453|uniprotkb:F5GWK4|ensembl:ENSP00000419413 psi-mi:sox2_human(display_long)|uniprotkb:SOX2(gene name)|psi-mi:SOX2(display_short) psi-mi:armc8_human(display_long)|uniprotkb:ARMC8(gene name)|psi-mi:ARMC8(display_short)|uniprotkb:S863-2(orf name) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Cox et al. (2012) pubmed:23667531|imex:IM-28599 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-26574478|imex:IM-28599-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_003097.1|dip:DIP-59913N|ensembl:ENSG00000181449(gene)|ensembl:ENST00000325404(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001649"(osteoblast differentiation)|go:"GO:0001654"(eye development)|go:"GO:0001714"(endodermal cell fate specification)|go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006325"(chromatin organization)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0009611"(response to wounding)|go:"GO:0009653"(anatomical structure morphogenesis)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0021781"(glial cell fate commitment)|go:"GO:0021983"(pituitary gland development)|go:"GO:0021984"(adenohypophysis development)|go:"GO:0022409"(positive regulation of cell-cell adhesion)|go:"GO:0030154"(cell differentiation)|go:"GO:0030900"(forebrain development)|go:"GO:0035019"(somatic stem cell population maintenance)|go:"GO:0035198"(miRNA binding)|go:"GO:0042246"(tissue regeneration)|go:"GO:0043281"(regulation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0043410"(positive regulation of MAPK cascade)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045165"(cell fate commitment)|go:"GO:0045597"(positive regulation of cell differentiation)|go:"GO:0045665"(negative regulation of neuron differentiation)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048839"(inner ear development)|go:"GO:0050680"(negative regulation of epithelial cell proliferation)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0070848"(response to growth factor)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:0097150"(neuronal stem cell population maintenance)|interpro:IPR009071(High mobility group box, HMG)|interpro:IPR022097|interpro:IPR032643|interpro:IPR036910|mint:P48431|rcsb pdb:1O4X|rcsb pdb:2LE4|rcsb pdb:6T7B|rcsb pdb:6T90|rcsb pdb:6WX7|rcsb pdb:6WX8|rcsb pdb:6WX9|rcsb pdb:6YOV|reactome:R-HSA-2892245|reactome:R-HSA-2892247|reactome:R-HSA-3769402|reactome:R-HSA-452723|reactome:R-HSA-6785807|reactome:R-HSA-8986944 refseq:NP_054873.2|refseq:NP_056211.2|refseq:NP_998819.1|refseq:XP_011510934.1|refseq:XP_011510935.1|refseq:NP_001253970.1|refseq:NP_001253971.1|refseq:NP_001269271.1|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0034657"(GID complex)|go:"GO:0035580"(specific granule lumen)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:1904724"(tertiary granule lumen)|interpro:IPR000225(Armadillo)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR038739|mint:Q8IUR7|rcsb pdb:7NSC|reactome:R-HSA-6798695|ensembl:ENSG00000114098(gene)|ensembl:ENST00000469044(transcript)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0005576"(extracellular region)|refseq:XP_006713627.1|refseq:XP_006713628.1|refseq:XP_006713629.1 go:"GO:0005634"(nucleus) - - figure legend:ST3 F2C|comment:proteins that were enriched in the induced sample more than 6-fold|dataset:Brain Disease - Neurological Diseases & Disorders|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-daoy)|taxid:9606(Homo sapiens DAOY cerebellar medulloblastoma cell line) - 2020/12/29 2020/12/29 rogid:cn8gYfKDpQc8J2ygnqny32sIyyU9606 rogid:9QXdCIwU8zeZ94oQ7JJNDVD2NDk9606 rigid:Cnhili6Os5i+9KsmWx3iqclZGC0 false tandem tag:n-n - - - psi-mi:"MI:0658"(multidimensional protein identification technology) psi-mi:"MI:0658"(multidimensional protein identification technology) uniprotkb:P48431 uniprotkb:Q99575 intact:EBI-6124081|uniprotkb:Q14537|ensembl:ENSP00000323588 intact:EBI-366741|uniprotkb:Q15037|uniprotkb:A8K5W9|intact:EBI-2560204|ensembl:ENSP00000339529|ensembl:ENSP00000385787 psi-mi:sox2_human(display_long)|uniprotkb:SOX2(gene name)|psi-mi:SOX2(display_short) psi-mi:pop1_human(display_long)|uniprotkb:POP1(gene name)|psi-mi:POP1(display_short)|uniprotkb:KIAA0061(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Cox et al. (2012) pubmed:23667531|imex:IM-28599 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-26574478|imex:IM-28599-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_003097.1|dip:DIP-59913N|ensembl:ENSG00000181449(gene)|ensembl:ENST00000325404(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001649"(osteoblast differentiation)|go:"GO:0001654"(eye development)|go:"GO:0001714"(endodermal cell fate specification)|go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006325"(chromatin organization)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0009611"(response to wounding)|go:"GO:0009653"(anatomical structure morphogenesis)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0021781"(glial cell fate commitment)|go:"GO:0021983"(pituitary gland development)|go:"GO:0021984"(adenohypophysis development)|go:"GO:0022409"(positive regulation of cell-cell adhesion)|go:"GO:0030154"(cell differentiation)|go:"GO:0030900"(forebrain development)|go:"GO:0035019"(somatic stem cell population maintenance)|go:"GO:0035198"(miRNA binding)|go:"GO:0042246"(tissue regeneration)|go:"GO:0043281"(regulation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0043410"(positive regulation of MAPK cascade)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045165"(cell fate commitment)|go:"GO:0045597"(positive regulation of cell differentiation)|go:"GO:0045665"(negative regulation of neuron differentiation)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048839"(inner ear development)|go:"GO:0050680"(negative regulation of epithelial cell proliferation)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0070848"(response to growth factor)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:0097150"(neuronal stem cell population maintenance)|interpro:IPR009071(High mobility group box, HMG)|interpro:IPR022097|interpro:IPR032643|interpro:IPR036910|mint:P48431|rcsb pdb:1O4X|rcsb pdb:2LE4|rcsb pdb:6T7B|rcsb pdb:6T90|rcsb pdb:6WX7|rcsb pdb:6WX8|rcsb pdb:6WX9|rcsb pdb:6YOV|reactome:R-HSA-2892245|reactome:R-HSA-2892247|reactome:R-HSA-3769402|reactome:R-HSA-452723|reactome:R-HSA-6785807|reactome:R-HSA-8986944 refseq:NP_001139332.1|refseq:NP_001139333.1|refseq:NP_055844.2|ensembl:ENSG00000104356(gene)|ensembl:ENST00000349693(transcript)|ensembl:ENST00000401707(transcript)|go:"GO:0000172"(ribonuclease MRP complex)|go:"GO:0001682"(tRNA 5'-leader removal)|go:"GO:0003723"(RNA binding)|go:"GO:0004526"(ribonuclease P activity)|go:"GO:0005615"(extracellular space)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005655"(nucleolar ribonuclease P complex)|go:"GO:0005730"(nucleolus)|go:"GO:0008033"(tRNA processing)|go:"GO:0016078"(tRNA catabolic process)|go:"GO:0030681"(multimeric ribonuclease P complex)|go:"GO:0033204"(ribonuclease P RNA binding)|go:"GO:0090502"(RNA phosphodiester bond hydrolysis, endonucleolytic)|interpro:IPR009723(Ribonuclease P/MRP, POP1)|interpro:IPR012590(POPLD)|interpro:IPR039182|mint:Q99575|rcsb pdb:6AHR|rcsb pdb:6AHU|reactome:R-HSA-6784531 go:"GO:0005634"(nucleus) - - figure legend:ST3 F2C|comment:proteins that were enriched in the induced sample more than 6-fold|dataset:Brain Disease - Neurological Diseases & Disorders|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-daoy)|taxid:9606(Homo sapiens DAOY cerebellar medulloblastoma cell line) - 2020/12/29 2020/12/29 rogid:cn8gYfKDpQc8J2ygnqny32sIyyU9606 rogid:XJxSr17TfVuetXKgpQPjs2QKMV49606 rigid:Cnhili6Os5i+9KsmWx3iqclZGC0 false tandem tag:n-n - - - psi-mi:"MI:0658"(multidimensional protein identification technology) psi-mi:"MI:0658"(multidimensional protein identification technology) uniprotkb:P48431 uniprotkb:Q8IZL8 intact:EBI-6124081|uniprotkb:Q14537|ensembl:ENSP00000323588 intact:EBI-716449|intact:EBI-28969510|ensembl:ENSP00000460300|ensembl:ENSP00000461625|uniprotkb:O15450|uniprotkb:Q5EGN3|uniprotkb:Q6NTE6|uniprotkb:Q96FT1|uniprotkb:Q9BU60 psi-mi:sox2_human(display_long)|uniprotkb:SOX2(gene name)|psi-mi:SOX2(display_short) psi-mi:pelp1_human(display_long)|uniprotkb:Modulator of non-genomic activity of estrogen receptor(gene name synonym)|uniprotkb:Transcription factor HMX3(gene name synonym)|uniprotkb:PELP1(gene name)|psi-mi:PELP1(display_short)|uniprotkb:HMX3(gene name synonym)|uniprotkb:MNAR(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Cox et al. (2012) pubmed:23667531|imex:IM-28599 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-26574478|imex:IM-28599-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_003097.1|dip:DIP-59913N|ensembl:ENSG00000181449(gene)|ensembl:ENST00000325404(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001649"(osteoblast differentiation)|go:"GO:0001654"(eye development)|go:"GO:0001714"(endodermal cell fate specification)|go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006325"(chromatin organization)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0009611"(response to wounding)|go:"GO:0009653"(anatomical structure morphogenesis)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0021781"(glial cell fate commitment)|go:"GO:0021983"(pituitary gland development)|go:"GO:0021984"(adenohypophysis development)|go:"GO:0022409"(positive regulation of cell-cell adhesion)|go:"GO:0030154"(cell differentiation)|go:"GO:0030900"(forebrain development)|go:"GO:0035019"(somatic stem cell population maintenance)|go:"GO:0035198"(miRNA binding)|go:"GO:0042246"(tissue regeneration)|go:"GO:0043281"(regulation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0043410"(positive regulation of MAPK cascade)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045165"(cell fate commitment)|go:"GO:0045597"(positive regulation of cell differentiation)|go:"GO:0045665"(negative regulation of neuron differentiation)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048839"(inner ear development)|go:"GO:0050680"(negative regulation of epithelial cell proliferation)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0070848"(response to growth factor)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:0097150"(neuronal stem cell population maintenance)|interpro:IPR009071(High mobility group box, HMG)|interpro:IPR022097|interpro:IPR032643|interpro:IPR036910|mint:P48431|rcsb pdb:1O4X|rcsb pdb:2LE4|rcsb pdb:6T7B|rcsb pdb:6T90|rcsb pdb:6WX7|rcsb pdb:6WX8|rcsb pdb:6WX9|rcsb pdb:6YOV|reactome:R-HSA-2892245|reactome:R-HSA-2892247|reactome:R-HSA-3769402|reactome:R-HSA-452723|reactome:R-HSA-6785807|reactome:R-HSA-8986944 ensembl:ENSG00000141456(gene)|ensembl:ENST00000572293(transcript)|ensembl:ENST00000574876(transcript)|go:"GO:0003682"(chromatin binding)|go:"GO:0003723"(RNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0008134"(transcription factor binding)|go:"GO:0016020"(membrane)|go:"GO:0035327"|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0071339"(MLL1 complex)|go:"GO:0071391"(cellular response to estrogen stimulus)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR012583(NUC201)|interpro:IPR016024(Armadillo-type fold)|mint:Q8IZL8|reactome:R-HSA-6791226|reactome:R-HSA-8849473|interpro:IPR012980(Protein of unknown function NUC202)|ensembl:ENSP00000460300|ensembl:ENSP00000461625|refseq:NP_055204.3|refseq:NP_001265170.1 go:"GO:0005634"(nucleus) - - figure legend:ST3 F2C|comment:proteins that were enriched in the induced sample more than 6-fold|dataset:Brain Disease - Neurological Diseases & Disorders|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-daoy)|taxid:9606(Homo sapiens DAOY cerebellar medulloblastoma cell line) - 2020/12/29 2020/12/29 rogid:cn8gYfKDpQc8J2ygnqny32sIyyU9606 rogid:iu03DsintVoo3gWzZX14SlHE0ao9606 rigid:Cnhili6Os5i+9KsmWx3iqclZGC0 false tandem tag:n-n - - - psi-mi:"MI:0658"(multidimensional protein identification technology) psi-mi:"MI:0658"(multidimensional protein identification technology) uniprotkb:P48431 uniprotkb:O60884 intact:EBI-6124081|uniprotkb:Q14537|ensembl:ENSP00000323588 intact:EBI-352957|ensembl:ENSP00000314030|uniprotkb:O14711|uniprotkb:B2R7L7 psi-mi:sox2_human(display_long)|uniprotkb:SOX2(gene name)|psi-mi:SOX2(display_short) psi-mi:dnja2_human(display_long)|uniprotkb:DNAJA2(gene name)|psi-mi:DNAJA2(display_short)|uniprotkb:HIRIP4(gene name synonym)|uniprotkb:CPR3(gene name synonym)|uniprotkb:HIRA-interacting protein 4(gene name synonym)|uniprotkb:Cell cycle progression restoration gene 3 protein(gene name synonym)|uniprotkb:Dnj3(gene name synonym)|uniprotkb:Renal carcinoma antigen NY-REN-14(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Cox et al. (2012) pubmed:23667531|imex:IM-28599 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-26574478|imex:IM-28599-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_003097.1|dip:DIP-59913N|ensembl:ENSG00000181449(gene)|ensembl:ENST00000325404(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001649"(osteoblast differentiation)|go:"GO:0001654"(eye development)|go:"GO:0001714"(endodermal cell fate specification)|go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006325"(chromatin organization)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0009611"(response to wounding)|go:"GO:0009653"(anatomical structure morphogenesis)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0021781"(glial cell fate commitment)|go:"GO:0021983"(pituitary gland development)|go:"GO:0021984"(adenohypophysis development)|go:"GO:0022409"(positive regulation of cell-cell adhesion)|go:"GO:0030154"(cell differentiation)|go:"GO:0030900"(forebrain development)|go:"GO:0035019"(somatic stem cell population maintenance)|go:"GO:0035198"(miRNA binding)|go:"GO:0042246"(tissue regeneration)|go:"GO:0043281"(regulation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0043410"(positive regulation of MAPK cascade)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045165"(cell fate commitment)|go:"GO:0045597"(positive regulation of cell differentiation)|go:"GO:0045665"(negative regulation of neuron differentiation)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048839"(inner ear development)|go:"GO:0050680"(negative regulation of epithelial cell proliferation)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0070848"(response to growth factor)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:0097150"(neuronal stem cell population maintenance)|interpro:IPR009071(High mobility group box, HMG)|interpro:IPR022097|interpro:IPR032643|interpro:IPR036910|mint:P48431|rcsb pdb:1O4X|rcsb pdb:2LE4|rcsb pdb:6T7B|rcsb pdb:6T90|rcsb pdb:6WX7|rcsb pdb:6WX8|rcsb pdb:6WX9|rcsb pdb:6YOV|reactome:R-HSA-2892245|reactome:R-HSA-2892247|reactome:R-HSA-3769402|reactome:R-HSA-452723|reactome:R-HSA-6785807|reactome:R-HSA-8986944 ensembl:ENSG00000069345(gene)|ensembl:ENST00000317089(transcript)|go:"GO:0001671"(ATPase activator activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005829"(cytosol)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0009408"(response to heat)|go:"GO:0016020"(membrane)|go:"GO:0030544"(Hsp70 protein binding)|go:"GO:0042026"(protein refolding)|go:"GO:0046872"(metal ion binding)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0051087"(chaperone binding)|go:"GO:0070062"(extracellular exosome)|interpro:IPR001305(Heat shock protein DnaJ, cysteine-rich region)|interpro:IPR001623(Heat shock protein DnaJ, N-terminal)|interpro:IPR002939(Chaperone DnaJ, C-terminal)|interpro:IPR008971(HSP40/DnaJ peptide-binding)|interpro:IPR012724(Chaperone DnaJ)|interpro:IPR036410|interpro:IPR036869|interpro:IPR044713|mint:O60884|reactome:R-HSA-3371497|interpro:IPR018253|refseq:NP_005871.1|dip:DIP-33143N go:"GO:0005634"(nucleus) - - figure legend:ST3 F2C|comment:proteins that were enriched in the induced sample more than 6-fold|dataset:Brain Disease - Neurological Diseases & Disorders|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-daoy)|taxid:9606(Homo sapiens DAOY cerebellar medulloblastoma cell line) - 2020/12/29 2020/12/29 rogid:cn8gYfKDpQc8J2ygnqny32sIyyU9606 rogid:c+JdHn0cKVKqRZCvK6DRYWs+zkQ9606 rigid:Cnhili6Os5i+9KsmWx3iqclZGC0 false tandem tag:n-n - - - psi-mi:"MI:0658"(multidimensional protein identification technology) psi-mi:"MI:0658"(multidimensional protein identification technology) uniprotkb:P48431 uniprotkb:Q9Y4W2 intact:EBI-6124081|uniprotkb:Q14537|ensembl:ENSP00000323588 intact:EBI-1051591|uniprotkb:Q5JXQ0|uniprotkb:Q8TEN5|uniprotkb:Q9H9V5|uniprotkb:A9X410|ensembl:ENSP00000363944 psi-mi:sox2_human(display_long)|uniprotkb:SOX2(gene name)|psi-mi:SOX2(display_short) psi-mi:las1l_human(display_long)|uniprotkb:LAS1L(gene name)|psi-mi:LAS1L(display_short)|uniprotkb:Protein LAS1 homolog(gene name synonym)|uniprotkb:MSTP060(orf name) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Cox et al. (2012) pubmed:23667531|imex:IM-28599 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-26574478|imex:IM-28599-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_003097.1|dip:DIP-59913N|ensembl:ENSG00000181449(gene)|ensembl:ENST00000325404(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001649"(osteoblast differentiation)|go:"GO:0001654"(eye development)|go:"GO:0001714"(endodermal cell fate specification)|go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006325"(chromatin organization)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0009611"(response to wounding)|go:"GO:0009653"(anatomical structure morphogenesis)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0021781"(glial cell fate commitment)|go:"GO:0021983"(pituitary gland development)|go:"GO:0021984"(adenohypophysis development)|go:"GO:0022409"(positive regulation of cell-cell adhesion)|go:"GO:0030154"(cell differentiation)|go:"GO:0030900"(forebrain development)|go:"GO:0035019"(somatic stem cell population maintenance)|go:"GO:0035198"(miRNA binding)|go:"GO:0042246"(tissue regeneration)|go:"GO:0043281"(regulation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0043410"(positive regulation of MAPK cascade)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045165"(cell fate commitment)|go:"GO:0045597"(positive regulation of cell differentiation)|go:"GO:0045665"(negative regulation of neuron differentiation)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048839"(inner ear development)|go:"GO:0050680"(negative regulation of epithelial cell proliferation)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0070848"(response to growth factor)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:0097150"(neuronal stem cell population maintenance)|interpro:IPR009071(High mobility group box, HMG)|interpro:IPR022097|interpro:IPR032643|interpro:IPR036910|mint:P48431|rcsb pdb:1O4X|rcsb pdb:2LE4|rcsb pdb:6T7B|rcsb pdb:6T90|rcsb pdb:6WX7|rcsb pdb:6WX8|rcsb pdb:6WX9|rcsb pdb:6YOV|reactome:R-HSA-2892245|reactome:R-HSA-2892247|reactome:R-HSA-3769402|reactome:R-HSA-452723|reactome:R-HSA-6785807|reactome:R-HSA-8986944 refseq:NP_001164120.1|refseq:NP_001164121.1|refseq:NP_112483.1|ensembl:ENSG00000001497(gene)|ensembl:ENST00000374811(transcript)|go:"GO:0000460"(maturation of 5.8S rRNA)|go:"GO:0000470"(maturation of LSU-rRNA)|go:"GO:0003723"(RNA binding)|go:"GO:0004519"(endonuclease activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0016020"(membrane)|go:"GO:0030687"(preribosome, large subunit precursor)|go:"GO:0071339"(MLL1 complex)|go:"GO:0090730"(Las1 complex)|interpro:IPR007174(Las1-like)|mint:Q9Y4W2|reactome:R-HSA-6791226 go:"GO:0005634"(nucleus) - - figure legend:ST3 F2C|comment:proteins that were enriched in the induced sample more than 6-fold|dataset:Brain Disease - Neurological Diseases & Disorders|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-daoy)|taxid:9606(Homo sapiens DAOY cerebellar medulloblastoma cell line) - 2020/12/29 2020/12/29 rogid:cn8gYfKDpQc8J2ygnqny32sIyyU9606 rogid:1TTE2TCMIwczNaT2SSMLioLkALA9606 rigid:Cnhili6Os5i+9KsmWx3iqclZGC0 false tandem tag:n-n - - - psi-mi:"MI:0658"(multidimensional protein identification technology) psi-mi:"MI:0658"(multidimensional protein identification technology) uniprotkb:P48431 uniprotkb:P19784 intact:EBI-6124081|uniprotkb:Q14537|ensembl:ENSP00000323588 intact:EBI-347451|ensembl:ENSP00000262506 psi-mi:sox2_human(display_long)|uniprotkb:SOX2(gene name)|psi-mi:SOX2(display_short) psi-mi:csk22_human(display_long)|uniprotkb:CSNK2A2(gene name)|psi-mi:CSNK2A2(display_short)|uniprotkb:CK2A2(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Cox et al. (2012) pubmed:23667531|imex:IM-28599 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-26574478|imex:IM-28599-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_003097.1|dip:DIP-59913N|ensembl:ENSG00000181449(gene)|ensembl:ENST00000325404(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001649"(osteoblast differentiation)|go:"GO:0001654"(eye development)|go:"GO:0001714"(endodermal cell fate specification)|go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006325"(chromatin organization)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0009611"(response to wounding)|go:"GO:0009653"(anatomical structure morphogenesis)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0021781"(glial cell fate commitment)|go:"GO:0021983"(pituitary gland development)|go:"GO:0021984"(adenohypophysis development)|go:"GO:0022409"(positive regulation of cell-cell adhesion)|go:"GO:0030154"(cell differentiation)|go:"GO:0030900"(forebrain development)|go:"GO:0035019"(somatic stem cell population maintenance)|go:"GO:0035198"(miRNA binding)|go:"GO:0042246"(tissue regeneration)|go:"GO:0043281"(regulation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0043410"(positive regulation of MAPK cascade)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045165"(cell fate commitment)|go:"GO:0045597"(positive regulation of cell differentiation)|go:"GO:0045665"(negative regulation of neuron differentiation)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048839"(inner ear development)|go:"GO:0050680"(negative regulation of epithelial cell proliferation)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0070848"(response to growth factor)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:0097150"(neuronal stem cell population maintenance)|interpro:IPR009071(High mobility group box, HMG)|interpro:IPR022097|interpro:IPR032643|interpro:IPR036910|mint:P48431|rcsb pdb:1O4X|rcsb pdb:2LE4|rcsb pdb:6T7B|rcsb pdb:6T90|rcsb pdb:6WX7|rcsb pdb:6WX8|rcsb pdb:6WX9|rcsb pdb:6YOV|reactome:R-HSA-2892245|reactome:R-HSA-2892247|reactome:R-HSA-3769402|reactome:R-HSA-452723|reactome:R-HSA-6785807|reactome:R-HSA-8986944 refseq:NP_001887.1|dip:DIP-318N|ensembl:ENSG00000070770(gene)|ensembl:ENST00000262506(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0001669"(acrosomal vesicle)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005956"(protein kinase CK2 complex)|go:"GO:0006915"(apoptotic process)|go:"GO:0007049"(cell cycle)|go:"GO:0007283"(spermatogenesis)|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0018105"(peptidyl-serine phosphorylation)|go:"GO:0018107"(peptidyl-threonine phosphorylation)|go:"GO:0021987"(cerebral cortex development)|go:"GO:0047485"(protein N-terminus binding)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0097421"(liver regeneration)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:1903146"(regulation of autophagy of mitochondrion)|go:"GO:1903955"(positive regulation of protein targeting to mitochondrion)|go:"GO:1905818"(regulation of chromosome separation)|go:"GO:2000059"(negative regulation of ubiquitin-dependent protein catabolic process)|go:"GO:2001234"(negative regulation of apoptotic signaling pathway)|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|mint:P19784|rcsb pdb:3E3B|rcsb pdb:3OFM|rcsb pdb:3U87|rcsb pdb:5M4U|rcsb pdb:5M56|rcsb pdb:5OOI|rcsb pdb:5Y9M|rcsb pdb:5YF9|rcsb pdb:5YWM|rcsb pdb:6HMB|rcsb pdb:6HMC|rcsb pdb:6HMD|rcsb pdb:6HMQ|rcsb pdb:6L20|rcsb pdb:6QY8|rcsb pdb:6QY9|rcsb pdb:6TE2|rcsb pdb:6TEW|rcsb pdb:6TGU|rcsb pdb:7A1B|rcsb pdb:7A1Z|rcsb pdb:7A22|rcsb pdb:7A2H|reactome:R-HSA-1483191|reactome:R-HSA-201688|reactome:R-HSA-2514853|reactome:R-HSA-445144|reactome:R-HSA-6804756|reactome:R-HSA-6814122|reactome:R-HSA-8932339|reactome:R-HSA-8934903|reactome:R-HSA-8939243|reactome:R-HSA-8948751 go:"GO:0005634"(nucleus) - - figure legend:ST3 F2C|comment:proteins that were enriched in the induced sample more than 6-fold|dataset:Brain Disease - Neurological Diseases & Disorders|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-daoy)|taxid:9606(Homo sapiens DAOY cerebellar medulloblastoma cell line) - 2020/12/29 2020/12/29 rogid:cn8gYfKDpQc8J2ygnqny32sIyyU9606 rogid:SIekW2yzNePP9hLKW7OHNFBwNck9606 rigid:Cnhili6Os5i+9KsmWx3iqclZGC0 false tandem tag:n-n - - - psi-mi:"MI:0658"(multidimensional protein identification technology) psi-mi:"MI:0658"(multidimensional protein identification technology) uniprotkb:P48431 uniprotkb:Q9NV88 intact:EBI-6124081|uniprotkb:Q14537|ensembl:ENSP00000323588 intact:EBI-2866634|uniprotkb:O00224|uniprotkb:Q8TB16|uniprotkb:B7Z6M5|uniprotkb:B7Z560|ensembl:ENSP00000429065 psi-mi:sox2_human(display_long)|uniprotkb:SOX2(gene name)|psi-mi:SOX2(display_short) psi-mi:int9_human(display_long)|uniprotkb:INTS9(gene name)|psi-mi:INTS9(display_short)|uniprotkb:RC74(gene name synonym)|uniprotkb:Protein related to CPSF subunits of 74 kDa(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Cox et al. (2012) pubmed:23667531|imex:IM-28599 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-26574478|imex:IM-28599-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_003097.1|dip:DIP-59913N|ensembl:ENSG00000181449(gene)|ensembl:ENST00000325404(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001649"(osteoblast differentiation)|go:"GO:0001654"(eye development)|go:"GO:0001714"(endodermal cell fate specification)|go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006325"(chromatin organization)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0009611"(response to wounding)|go:"GO:0009653"(anatomical structure morphogenesis)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0021781"(glial cell fate commitment)|go:"GO:0021983"(pituitary gland development)|go:"GO:0021984"(adenohypophysis development)|go:"GO:0022409"(positive regulation of cell-cell adhesion)|go:"GO:0030154"(cell differentiation)|go:"GO:0030900"(forebrain development)|go:"GO:0035019"(somatic stem cell population maintenance)|go:"GO:0035198"(miRNA binding)|go:"GO:0042246"(tissue regeneration)|go:"GO:0043281"(regulation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0043410"(positive regulation of MAPK cascade)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045165"(cell fate commitment)|go:"GO:0045597"(positive regulation of cell differentiation)|go:"GO:0045665"(negative regulation of neuron differentiation)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048839"(inner ear development)|go:"GO:0050680"(negative regulation of epithelial cell proliferation)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0070848"(response to growth factor)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:0097150"(neuronal stem cell population maintenance)|interpro:IPR009071(High mobility group box, HMG)|interpro:IPR022097|interpro:IPR032643|interpro:IPR036910|mint:P48431|rcsb pdb:1O4X|rcsb pdb:2LE4|rcsb pdb:6T7B|rcsb pdb:6T90|rcsb pdb:6WX7|rcsb pdb:6WX8|rcsb pdb:6WX9|rcsb pdb:6YOV|reactome:R-HSA-2892245|reactome:R-HSA-2892247|reactome:R-HSA-3769402|reactome:R-HSA-452723|reactome:R-HSA-6785807|reactome:R-HSA-8986944 refseq:NP_001138631.1|refseq:NP_060720.2|refseq:NP_001166033.1|ensembl:ENSG00000104299(gene)|ensembl:ENST00000521022(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0016180"(snRNA processing)|go:"GO:0032039"(integrator complex)|interpro:IPR001279(Beta-lactamase-like)|interpro:IPR022712|interpro:IPR027074|interpro:IPR036866|mint:Q9NV88|rcsb pdb:5V8W|rcsb pdb:7BFP|rcsb pdb:7BFQ|rcsb pdb:7CUN|reactome:R-HSA-6807505 go:"GO:0005634"(nucleus) - - figure legend:ST3 F2C|comment:proteins that were enriched in the induced sample more than 6-fold|dataset:Brain Disease - Neurological Diseases & Disorders|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-daoy)|taxid:9606(Homo sapiens DAOY cerebellar medulloblastoma cell line) - 2020/12/29 2020/12/29 rogid:cn8gYfKDpQc8J2ygnqny32sIyyU9606 rogid:ShAqPc3dCrs+ixK2yO7PqGVSI/U9606 rigid:Cnhili6Os5i+9KsmWx3iqclZGC0 false tandem tag:n-n - - - psi-mi:"MI:0658"(multidimensional protein identification technology) psi-mi:"MI:0658"(multidimensional protein identification technology) uniprotkb:P48431 uniprotkb:Q15021 intact:EBI-6124081|uniprotkb:Q14537|ensembl:ENSP00000323588 intact:EBI-1044041|uniprotkb:Q8N6U3|ensembl:ENSP00000325017|uniprotkb:D3DUR4 psi-mi:sox2_human(display_long)|uniprotkb:SOX2(gene name)|psi-mi:SOX2(display_short) psi-mi:cnd1_human(display_long)|uniprotkb:NCAPD2(gene name)|psi-mi:NCAPD2(display_short)|uniprotkb:CAPD2(gene name synonym)|uniprotkb:KIAA0159(gene name synonym)|uniprotkb:Non-SMC condensin I complex subunit D2(gene name synonym)|uniprotkb:Chromosome condensation-related SMC-associated protein 1(gene name synonym)|uniprotkb:Chromosome-associated protein D2(gene name synonym)|uniprotkb:XCAP-D2 homolog(gene name synonym)|uniprotkb:CNAP1(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Cox et al. (2012) pubmed:23667531|imex:IM-28599 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-26574478|imex:IM-28599-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_003097.1|dip:DIP-59913N|ensembl:ENSG00000181449(gene)|ensembl:ENST00000325404(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001649"(osteoblast differentiation)|go:"GO:0001654"(eye development)|go:"GO:0001714"(endodermal cell fate specification)|go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006325"(chromatin organization)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0009611"(response to wounding)|go:"GO:0009653"(anatomical structure morphogenesis)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0021781"(glial cell fate commitment)|go:"GO:0021983"(pituitary gland development)|go:"GO:0021984"(adenohypophysis development)|go:"GO:0022409"(positive regulation of cell-cell adhesion)|go:"GO:0030154"(cell differentiation)|go:"GO:0030900"(forebrain development)|go:"GO:0035019"(somatic stem cell population maintenance)|go:"GO:0035198"(miRNA binding)|go:"GO:0042246"(tissue regeneration)|go:"GO:0043281"(regulation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0043410"(positive regulation of MAPK cascade)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045165"(cell fate commitment)|go:"GO:0045597"(positive regulation of cell differentiation)|go:"GO:0045665"(negative regulation of neuron differentiation)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048839"(inner ear development)|go:"GO:0050680"(negative regulation of epithelial cell proliferation)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0070848"(response to growth factor)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:0097150"(neuronal stem cell population maintenance)|interpro:IPR009071(High mobility group box, HMG)|interpro:IPR022097|interpro:IPR032643|interpro:IPR036910|mint:P48431|rcsb pdb:1O4X|rcsb pdb:2LE4|rcsb pdb:6T7B|rcsb pdb:6T90|rcsb pdb:6WX7|rcsb pdb:6WX8|rcsb pdb:6WX9|rcsb pdb:6YOV|reactome:R-HSA-2892245|reactome:R-HSA-2892247|reactome:R-HSA-3769402|reactome:R-HSA-452723|reactome:R-HSA-6785807|reactome:R-HSA-8986944 refseq:NP_055680.3|ensembl:ENSG00000010292(gene)|ensembl:ENST00000315579(transcript)|go:"GO:0000779"(condensed chromosome, centromeric region)|go:"GO:0000793"(condensed chromosome)|go:"GO:0000796"(condensin complex)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0007076"(mitotic chromosome condensation)|go:"GO:0010032"(meiotic chromosome condensation)|go:"GO:0016020"(membrane)|go:"GO:0042393"(histone binding)|go:"GO:0051301"(cell division)|interpro:IPR007673(Non-SMC condensin subunit, XCAP-D2/Cnd1)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR024324|interpro:IPR026971|interpro:IPR032682|mint:Q15021|reactome:R-HSA-2514853 go:"GO:0005634"(nucleus) - - figure legend:ST3 F2C|comment:proteins that were enriched in the induced sample more than 6-fold|dataset:Brain Disease - Neurological Diseases & Disorders|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-daoy)|taxid:9606(Homo sapiens DAOY cerebellar medulloblastoma cell line) - 2020/12/29 2020/12/29 rogid:cn8gYfKDpQc8J2ygnqny32sIyyU9606 rogid:lFz1E3CjOD76OsuGtokfR7Ujvnw9606 rigid:Cnhili6Os5i+9KsmWx3iqclZGC0 false tandem tag:n-n - - - psi-mi:"MI:0658"(multidimensional protein identification technology) psi-mi:"MI:0658"(multidimensional protein identification technology) uniprotkb:P48431 uniprotkb:Q93009 intact:EBI-6124081|uniprotkb:Q14537|ensembl:ENSP00000323588 intact:EBI-302474|uniprotkb:A6NMY8|intact:EBI-28988230|ensembl:ENSP00000343535|uniprotkb:B7Z815|uniprotkb:H0Y3G8 psi-mi:sox2_human(display_long)|uniprotkb:SOX2(gene name)|psi-mi:SOX2(display_short) psi-mi:ubp7_human(display_long)|uniprotkb:USP7(gene name)|psi-mi:USP7(display_short)|uniprotkb:HAUSP(gene name synonym)|uniprotkb:Ubiquitin thioesterase 7(gene name synonym)|uniprotkb:Ubiquitin-specific-processing protease 7(gene name synonym)|uniprotkb:Deubiquitinating enzyme 7(gene name synonym)|uniprotkb:Herpesvirus-associated ubiquitin-specific protease(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Cox et al. (2012) pubmed:23667531|imex:IM-28599 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-26574478|imex:IM-28599-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_003097.1|dip:DIP-59913N|ensembl:ENSG00000181449(gene)|ensembl:ENST00000325404(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001649"(osteoblast differentiation)|go:"GO:0001654"(eye development)|go:"GO:0001714"(endodermal cell fate specification)|go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006325"(chromatin organization)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0009611"(response to wounding)|go:"GO:0009653"(anatomical structure morphogenesis)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0021781"(glial cell fate commitment)|go:"GO:0021983"(pituitary gland development)|go:"GO:0021984"(adenohypophysis development)|go:"GO:0022409"(positive regulation of cell-cell adhesion)|go:"GO:0030154"(cell differentiation)|go:"GO:0030900"(forebrain development)|go:"GO:0035019"(somatic stem cell population maintenance)|go:"GO:0035198"(miRNA binding)|go:"GO:0042246"(tissue regeneration)|go:"GO:0043281"(regulation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0043410"(positive regulation of MAPK cascade)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045165"(cell fate commitment)|go:"GO:0045597"(positive regulation of cell differentiation)|go:"GO:0045665"(negative regulation of neuron differentiation)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048839"(inner ear development)|go:"GO:0050680"(negative regulation of epithelial cell proliferation)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0070848"(response to growth factor)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:0097150"(neuronal stem cell population maintenance)|interpro:IPR009071(High mobility group box, HMG)|interpro:IPR022097|interpro:IPR032643|interpro:IPR036910|mint:P48431|rcsb pdb:1O4X|rcsb pdb:2LE4|rcsb pdb:6T7B|rcsb pdb:6T90|rcsb pdb:6WX7|rcsb pdb:6WX8|rcsb pdb:6WX9|rcsb pdb:6YOV|reactome:R-HSA-2892245|reactome:R-HSA-2892247|reactome:R-HSA-3769402|reactome:R-HSA-452723|reactome:R-HSA-6785807|reactome:R-HSA-8986944 rcsb pdb:4PYZ|rcsb pdb:4WPH|rcsb pdb:4WPI|rcsb pdb:4YOC|rcsb pdb:4YSI|rcsb pdb:4Z96|rcsb pdb:4Z97|rcsb pdb:5C56|rcsb pdb:5C6D|rcsb pdb:5FWI|rcsb pdb:5GG4|rcsb pdb:5J7T|rcsb pdb:5JTJ|rcsb pdb:5JTV|rcsb pdb:5KYB|rcsb pdb:4M5X|rcsb pdb:5KYC|rcsb pdb:5KYD|rcsb pdb:5KYE|rcsb pdb:5KYF|interpro:IPR029346|interpro:IPR038765|mint:Q93009|rcsb pdb:1NB8|rcsb pdb:1NBF|rcsb pdb:1YY6|rcsb pdb:1YZE|rcsb pdb:2F1W|rcsb pdb:2F1X|rcsb pdb:2F1Y|rcsb pdb:2F1Z|rcsb pdb:2FOJ|rcsb pdb:2FOO|rcsb pdb:2FOP|rcsb pdb:2KVR|rcsb pdb:2XXN|rcsb pdb:2YLM|rcsb pdb:3MQR|rcsb pdb:3MQS|rcsb pdb:4JJQ|rcsb pdb:4KG9|rcsb pdb:4M5W|go:"GO:0006283"(transcription-coupled nucleotide-excision repair)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008134"(transcription factor binding)|go:"GO:0010216"(maintenance of DNA methylation)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0016579"(protein deubiquitination)|go:"GO:0016604"(nuclear body)|go:"GO:0016605"(PML body)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0031647"(regulation of protein stability)|go:"GO:0032088"(negative regulation of NF-kappaB transcription factor activity)|go:"GO:0032435"(negative regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035520"(monoubiquitinated protein deubiquitination)|go:"GO:0035616"(histone H2B conserved C-terminal lysine deubiquitination)|go:"GO:0042752"(regulation of circadian rhythm)|go:"GO:0048511"(rhythmic process)|go:"GO:0050821"(protein stabilization)|go:"GO:0051090"(regulation of DNA-binding transcription factor activity)|go:"GO:0070536"(protein K63-linked deubiquitination)|go:"GO:0101005"(deubiquitinase activity)|go:"GO:1901537"(positive regulation of DNA demethylation)|go:"GO:1901796"(regulation of signal transduction by p53 class mediator)|go:"GO:1904353"(regulation of telomere capping)|go:"GO:1905279"(regulation of retrograde transport, endosome to Golgi)|go:"GO:1990380"(Lys48-specific deubiquitinase activity)|interpro:IPR001394(Peptidase C19, ubiquitin carboxyl-terminal hydrolase 2)|interpro:IPR002083(MATH)|interpro:IPR008974(TRAF-like)|interpro:IPR018200|interpro:IPR024729|interpro:IPR028889|ensembl:ENSG00000187555(gene)|ensembl:ENST00000344836(transcript)|go:"GO:0002039"(p53 binding)|go:"GO:0004197"(cysteine-type endopeptidase activity)|go:"GO:0004843"(thiol-dependent deubiquitinase)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005694"(chromosome)|go:"GO:0005829"(cytosol)|go:"GO:0006111"(regulation of gluconeogenesis)|rcsb pdb:5N9R|rcsb pdb:5N9T|rcsb pdb:5NGE|rcsb pdb:5NGF|rcsb pdb:5UQV|rcsb pdb:5UQX|rcsb pdb:5VS6|rcsb pdb:5VSB|rcsb pdb:5VSK|rcsb pdb:5WHC|rcsb pdb:6F5H|rcsb pdb:6M1K|rcsb pdb:6P5L|rcsb pdb:6VN2|rcsb pdb:6VN3|rcsb pdb:6VN4|rcsb pdb:6VN5|rcsb pdb:6VN6|rcsb pdb:7CM2|reactome:R-HSA-5689880|reactome:R-HSA-6781823|reactome:R-HSA-6781827|reactome:R-HSA-6782135|reactome:R-HSA-6782210|reactome:R-HSA-6804757|reactome:R-HSA-8866652|reactome:R-HSA-8948747|refseq:NP_001273386.1|refseq:NP_003461.2|refseq:NP_001308787.1|ensembl:ENSP00000343535|ensembl:ENST00000381886|ensembl:ENSP00000371310|dip:DIP-29053N go:"GO:0005634"(nucleus) - - figure legend:ST3 F2C|comment:proteins that were enriched in the induced sample more than 6-fold|dataset:Brain Disease - Neurological Diseases & Disorders|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-daoy)|taxid:9606(Homo sapiens DAOY cerebellar medulloblastoma cell line) - 2020/12/29 2020/12/29 rogid:cn8gYfKDpQc8J2ygnqny32sIyyU9606 rogid:V+PXXBRM2zwlGQaeFiyjaQ9yf+A9606 rigid:Cnhili6Os5i+9KsmWx3iqclZGC0 false tandem tag:n-n - - - psi-mi:"MI:0658"(multidimensional protein identification technology) psi-mi:"MI:0658"(multidimensional protein identification technology) uniprotkb:P48431 uniprotkb:Q9HBE1 intact:EBI-6124081|uniprotkb:Q14537|ensembl:ENSP00000323588 intact:EBI-5459863|uniprotkb:Q9HBE2|uniprotkb:Q9HBE3|uniprotkb:Q9P1A9|uniprotkb:Q9UDU0|uniprotkb:Q9Y529|ensembl:ENSP00000266269 psi-mi:sox2_human(display_long)|uniprotkb:SOX2(gene name)|psi-mi:SOX2(display_short) psi-mi:patz1_human(display_long)|uniprotkb:PATZ1(gene name)|psi-mi:PATZ1(display_short)|uniprotkb:PATZ(gene name synonym)|uniprotkb:RIAZ(gene name synonym)|uniprotkb:ZBTB19(gene name synonym)|uniprotkb:ZNF278(gene name synonym)|uniprotkb:ZSG(gene name synonym)|uniprotkb:BTB/POZ domain zinc finger transcription factor(gene name synonym)|uniprotkb:Protein kinase A RI subunit alpha-associated protein(gene name synonym)|uniprotkb:Zinc finger and BTB domain-containing protein 19(gene name synonym)|uniprotkb:Zinc finger protein 278(gene name synonym)|uniprotkb:Zinc finger sarcoma gene protein(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Cox et al. (2012) pubmed:23667531|imex:IM-28599 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-26574478|imex:IM-28599-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_003097.1|dip:DIP-59913N|ensembl:ENSG00000181449(gene)|ensembl:ENST00000325404(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001649"(osteoblast differentiation)|go:"GO:0001654"(eye development)|go:"GO:0001714"(endodermal cell fate specification)|go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006325"(chromatin organization)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0009611"(response to wounding)|go:"GO:0009653"(anatomical structure morphogenesis)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0021781"(glial cell fate commitment)|go:"GO:0021983"(pituitary gland development)|go:"GO:0021984"(adenohypophysis development)|go:"GO:0022409"(positive regulation of cell-cell adhesion)|go:"GO:0030154"(cell differentiation)|go:"GO:0030900"(forebrain development)|go:"GO:0035019"(somatic stem cell population maintenance)|go:"GO:0035198"(miRNA binding)|go:"GO:0042246"(tissue regeneration)|go:"GO:0043281"(regulation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0043410"(positive regulation of MAPK cascade)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045165"(cell fate commitment)|go:"GO:0045597"(positive regulation of cell differentiation)|go:"GO:0045665"(negative regulation of neuron differentiation)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048839"(inner ear development)|go:"GO:0050680"(negative regulation of epithelial cell proliferation)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0070848"(response to growth factor)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:0097150"(neuronal stem cell population maintenance)|interpro:IPR009071(High mobility group box, HMG)|interpro:IPR022097|interpro:IPR032643|interpro:IPR036910|mint:P48431|rcsb pdb:1O4X|rcsb pdb:2LE4|rcsb pdb:6T7B|rcsb pdb:6T90|rcsb pdb:6WX7|rcsb pdb:6WX8|rcsb pdb:6WX9|rcsb pdb:6YOV|reactome:R-HSA-2892245|reactome:R-HSA-2892247|reactome:R-HSA-3769402|reactome:R-HSA-452723|reactome:R-HSA-6785807|reactome:R-HSA-8986944 refseq:NP_055138.2|refseq:NP_114439.1|refseq:NP_114440.1|refseq:NP_114441.1|ensembl:ENSG00000100105(gene)|ensembl:ENST00000266269(transcript)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007283"(spermatogenesis)|go:"GO:0008584"(male gonad development)|go:"GO:0010596"(negative regulation of endothelial cell migration)|go:"GO:0030217"(T cell differentiation)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0046872"(metal ion binding)|interpro:IPR000210(BTB/POZ-like)|interpro:IPR000637(HMG-I and HMG-Y, DNA-binding)|interpro:IPR011333(BTB/POZ fold)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR036236|mint:Q9HBE1|rcsb pdb:2EPP|rcsb pdb:2EPQ|rcsb pdb:2EPR|rcsb pdb:2EPS|rcsb pdb:2YT9 go:"GO:0005634"(nucleus) - - figure legend:ST3 F2C|comment:proteins that were enriched in the induced sample more than 6-fold|dataset:Brain Disease - Neurological Diseases & Disorders|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-daoy)|taxid:9606(Homo sapiens DAOY cerebellar medulloblastoma cell line) - 2020/12/29 2020/12/29 rogid:cn8gYfKDpQc8J2ygnqny32sIyyU9606 rogid:qj+3R6ELdhAtYeXe2YqGu+uOmqY9606 rigid:Cnhili6Os5i+9KsmWx3iqclZGC0 false tandem tag:n-n - - - psi-mi:"MI:0658"(multidimensional protein identification technology) psi-mi:"MI:0658"(multidimensional protein identification technology) uniprotkb:P48431 uniprotkb:P12268 intact:EBI-6124081|uniprotkb:Q14537|ensembl:ENSP00000323588 intact:EBI-353389|uniprotkb:Q6LEF3|ensembl:ENSP00000321584 psi-mi:sox2_human(display_long)|uniprotkb:SOX2(gene name)|psi-mi:SOX2(display_short) psi-mi:imdh2_human(display_long)|uniprotkb:IMPDH2(gene name)|psi-mi:IMPDH2(display_short)|uniprotkb:IMPD2(gene name synonym)|uniprotkb:Inosine-5'-monophosphate dehydrogenase type II(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Cox et al. (2012) pubmed:23667531|imex:IM-28599 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-26574478|imex:IM-28599-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_003097.1|dip:DIP-59913N|ensembl:ENSG00000181449(gene)|ensembl:ENST00000325404(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001649"(osteoblast differentiation)|go:"GO:0001654"(eye development)|go:"GO:0001714"(endodermal cell fate specification)|go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006325"(chromatin organization)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0009611"(response to wounding)|go:"GO:0009653"(anatomical structure morphogenesis)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0021781"(glial cell fate commitment)|go:"GO:0021983"(pituitary gland development)|go:"GO:0021984"(adenohypophysis development)|go:"GO:0022409"(positive regulation of cell-cell adhesion)|go:"GO:0030154"(cell differentiation)|go:"GO:0030900"(forebrain development)|go:"GO:0035019"(somatic stem cell population maintenance)|go:"GO:0035198"(miRNA binding)|go:"GO:0042246"(tissue regeneration)|go:"GO:0043281"(regulation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0043410"(positive regulation of MAPK cascade)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045165"(cell fate commitment)|go:"GO:0045597"(positive regulation of cell differentiation)|go:"GO:0045665"(negative regulation of neuron differentiation)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048839"(inner ear development)|go:"GO:0050680"(negative regulation of epithelial cell proliferation)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0070848"(response to growth factor)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:0097150"(neuronal stem cell population maintenance)|interpro:IPR009071(High mobility group box, HMG)|interpro:IPR022097|interpro:IPR032643|interpro:IPR036910|mint:P48431|rcsb pdb:1O4X|rcsb pdb:2LE4|rcsb pdb:6T7B|rcsb pdb:6T90|rcsb pdb:6WX7|rcsb pdb:6WX8|rcsb pdb:6WX9|rcsb pdb:6YOV|reactome:R-HSA-2892245|reactome:R-HSA-2892247|reactome:R-HSA-3769402|reactome:R-HSA-452723|reactome:R-HSA-6785807|reactome:R-HSA-8986944 refseq:NP_000875.2|ensembl:ENSG00000178035(gene)|ensembl:ENST00000326739(transcript)|go:"GO:0000166"(nucleotide binding)|go:"GO:0003677"(DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0003938"(IMP dehydrogenase activity)|go:"GO:0005576"(extracellular region)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005778"(peroxisomal membrane)|go:"GO:0005829"(cytosol)|go:"GO:0006177"(GMP biosynthetic process)|go:"GO:0006183"(GTP biosynthetic process)|go:"GO:0007623"(circadian rhythm)|go:"GO:0016020"(membrane)|go:"GO:0034774"(secretory granule lumen)|go:"GO:0042802"(identical protein binding)|go:"GO:0046651"(lymphocyte proliferation)|go:"GO:0046872"(metal ion binding)|go:"GO:0060041"(retina development in camera-type eye)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071353"(cellular response to interleukin-4)|go:"GO:1904813"(ficolin-1-rich granule lumen)|interpro:IPR000644(Cystathionine beta-synthase, core)|interpro:IPR001093(IMP dehydrogenase/GMP reductase)|interpro:IPR005990(IMP dehydrogenase)|interpro:IPR013785(Aldolase-type TIM barrel)|interpro:IPR015875(IMP dehydrogenase / GMP reductase, conserved site)|mint:P12268|rcsb pdb:1B3O|rcsb pdb:1NF7|rcsb pdb:1NFB|rcsb pdb:6I0M|rcsb pdb:6I0O|rcsb pdb:6U8E|rcsb pdb:6U8N|rcsb pdb:6U8R|rcsb pdb:6U8S|rcsb pdb:6U9O|rcsb pdb:6UA2|rcsb pdb:6UA4|rcsb pdb:6UA5|rcsb pdb:6UAJ|rcsb pdb:6UC2|rcsb pdb:6UDO|rcsb pdb:6UDP|rcsb pdb:6UDQ|reactome:R-HSA-6798695|reactome:R-HSA-73817|reactome:R-HSA-9679191 go:"GO:0005634"(nucleus) - - figure legend:ST3 F2C|comment:proteins that were enriched in the induced sample more than 6-fold|dataset:Brain Disease - Neurological Diseases & Disorders|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-daoy)|taxid:9606(Homo sapiens DAOY cerebellar medulloblastoma cell line) - 2020/12/29 2020/12/29 rogid:cn8gYfKDpQc8J2ygnqny32sIyyU9606 rogid:qGPwBxhEgtYik3OetHZbpyktoLE9606 rigid:Cnhili6Os5i+9KsmWx3iqclZGC0 false tandem tag:n-n - - - psi-mi:"MI:0658"(multidimensional protein identification technology) psi-mi:"MI:0658"(multidimensional protein identification technology) uniprotkb:P48431 uniprotkb:O43447 intact:EBI-6124081|uniprotkb:Q14537|ensembl:ENSP00000323588 intact:EBI-1055615|intact:EBI-6190037|uniprotkb:A6NNE7|ensembl:ENSP00000503384|ensembl:ENSP00000503489|ensembl:ENSP00000503922|ensembl:ENSP00000504108|ensembl:ENSP00000504595|ensembl:ENSP00000361630|ensembl:ENSP00000306614 psi-mi:sox2_human(display_long)|uniprotkb:SOX2(gene name)|psi-mi:SOX2(display_short) psi-mi:ppih_human(display_long)|uniprotkb:U-snRNP-associated cyclophilin SnuCyp-20(gene name synonym)|uniprotkb:Small nuclear ribonucleoprotein particle-specific cyclophilin H(gene name synonym)|uniprotkb:PPIH(gene name)|psi-mi:PPIH(display_short)|uniprotkb:CYP20(gene name synonym)|uniprotkb:CYPH(gene name synonym)|uniprotkb:Rotamase H(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Cox et al. (2012) pubmed:23667531|imex:IM-28599 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-26574478|imex:IM-28599-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_003097.1|dip:DIP-59913N|ensembl:ENSG00000181449(gene)|ensembl:ENST00000325404(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001649"(osteoblast differentiation)|go:"GO:0001654"(eye development)|go:"GO:0001714"(endodermal cell fate specification)|go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006325"(chromatin organization)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0009611"(response to wounding)|go:"GO:0009653"(anatomical structure morphogenesis)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0021781"(glial cell fate commitment)|go:"GO:0021983"(pituitary gland development)|go:"GO:0021984"(adenohypophysis development)|go:"GO:0022409"(positive regulation of cell-cell adhesion)|go:"GO:0030154"(cell differentiation)|go:"GO:0030900"(forebrain development)|go:"GO:0035019"(somatic stem cell population maintenance)|go:"GO:0035198"(miRNA binding)|go:"GO:0042246"(tissue regeneration)|go:"GO:0043281"(regulation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0043410"(positive regulation of MAPK cascade)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045165"(cell fate commitment)|go:"GO:0045597"(positive regulation of cell differentiation)|go:"GO:0045665"(negative regulation of neuron differentiation)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048839"(inner ear development)|go:"GO:0050680"(negative regulation of epithelial cell proliferation)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0070848"(response to growth factor)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:0097150"(neuronal stem cell population maintenance)|interpro:IPR009071(High mobility group box, HMG)|interpro:IPR022097|interpro:IPR032643|interpro:IPR036910|mint:P48431|rcsb pdb:1O4X|rcsb pdb:2LE4|rcsb pdb:6T7B|rcsb pdb:6T90|rcsb pdb:6WX7|rcsb pdb:6WX8|rcsb pdb:6WX9|rcsb pdb:6YOV|reactome:R-HSA-2892245|reactome:R-HSA-2892247|reactome:R-HSA-3769402|reactome:R-HSA-452723|reactome:R-HSA-6785807|reactome:R-HSA-8986944 refseq:NP_006338.1|refseq:XP_005270419.1|ensembl:ENST00000304979(transcript)|ensembl:ENST00000372550(transcript)|ensembl:ENST00000676675(transcript)|ensembl:ENST00000677900(transcript)|ensembl:ENST00000678038(transcript)|ensembl:ENST00000678333(transcript)|ensembl:ENST00000678803(transcript)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0000413"(protein peptidyl-prolyl isomerization)|go:"GO:0003755"(peptidyl-prolyl cis-trans isomerase activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005681"(spliceosomal complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0006457"(protein folding)|go:"GO:0016018"(cyclosporin A binding)|go:"GO:0016607"(nuclear speck)|go:"GO:0043021"(ribonucleoprotein complex binding)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0045070"(positive regulation of viral genome replication)|go:"GO:0046540"(U4/U6 x U5 tri-snRNP complex)|go:"GO:0065003"(protein-containing complex assembly)|go:"GO:0071001"(U4/U6 snRNP)|interpro:IPR002130(Peptidyl-prolyl cis-trans isomerase, cyclophilin-type)|interpro:IPR020892|interpro:IPR024936|interpro:IPR029000|mint:O43447|rcsb pdb:1MZW|rcsb pdb:1QOI|rcsb pdb:5O9Z|rcsb pdb:6AHD|reactome:R-HSA-72163|ensembl:ENSG00000171960(gene)|refseq:NP_001317439.1|refseq:XP_016855546.1|refseq:XP_016855547.1|refseq:XP_016855548.1 go:"GO:0005634"(nucleus) - - figure legend:ST3 F2C|comment:proteins that were enriched in the induced sample more than 6-fold|dataset:Brain Disease - Neurological Diseases & Disorders|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-daoy)|taxid:9606(Homo sapiens DAOY cerebellar medulloblastoma cell line) - 2020/12/29 2020/12/29 rogid:cn8gYfKDpQc8J2ygnqny32sIyyU9606 rogid:6gE98w/LLmT7FlCBnaBDk+GWvQU9606 rigid:Cnhili6Os5i+9KsmWx3iqclZGC0 false tandem tag:n-n - - - psi-mi:"MI:0658"(multidimensional protein identification technology) psi-mi:"MI:0658"(multidimensional protein identification technology) uniprotkb:P48431 uniprotkb:O00622 intact:EBI-6124081|uniprotkb:Q14537|ensembl:ENSP00000323588 intact:EBI-1237454|uniprotkb:O14934|uniprotkb:O43775|uniprotkb:Q9BZL7|ensembl:ENSP00000398736 psi-mi:sox2_human(display_long)|uniprotkb:SOX2(gene name)|psi-mi:SOX2(display_short) psi-mi:ccn1_human(display_long)|uniprotkb:CCN1(gene name)|psi-mi:CCN1(display_short)|uniprotkb:CYR61(gene name synonym)|uniprotkb:Cellular communication network factor 1(gene name synonym)|uniprotkb:Cysteine-rich angiogenic inducer 61(gene name synonym)|uniprotkb:GIG1(gene name synonym)|uniprotkb:IGFBP10(gene name synonym)|uniprotkb:Insulin-like growth factor-binding protein 10(gene name synonym)|uniprotkb:Protein CYR61(gene name synonym)|uniprotkb:Protein GIG1(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Cox et al. (2012) pubmed:23667531|imex:IM-28599 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-26574478|imex:IM-28599-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_003097.1|dip:DIP-59913N|ensembl:ENSG00000181449(gene)|ensembl:ENST00000325404(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001649"(osteoblast differentiation)|go:"GO:0001654"(eye development)|go:"GO:0001714"(endodermal cell fate specification)|go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006325"(chromatin organization)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0009611"(response to wounding)|go:"GO:0009653"(anatomical structure morphogenesis)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0021781"(glial cell fate commitment)|go:"GO:0021983"(pituitary gland development)|go:"GO:0021984"(adenohypophysis development)|go:"GO:0022409"(positive regulation of cell-cell adhesion)|go:"GO:0030154"(cell differentiation)|go:"GO:0030900"(forebrain development)|go:"GO:0035019"(somatic stem cell population maintenance)|go:"GO:0035198"(miRNA binding)|go:"GO:0042246"(tissue regeneration)|go:"GO:0043281"(regulation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0043410"(positive regulation of MAPK cascade)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045165"(cell fate commitment)|go:"GO:0045597"(positive regulation of cell differentiation)|go:"GO:0045665"(negative regulation of neuron differentiation)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048839"(inner ear development)|go:"GO:0050680"(negative regulation of epithelial cell proliferation)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0070848"(response to growth factor)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:0097150"(neuronal stem cell population maintenance)|interpro:IPR009071(High mobility group box, HMG)|interpro:IPR022097|interpro:IPR032643|interpro:IPR036910|mint:P48431|rcsb pdb:1O4X|rcsb pdb:2LE4|rcsb pdb:6T7B|rcsb pdb:6T90|rcsb pdb:6WX7|rcsb pdb:6WX8|rcsb pdb:6WX9|rcsb pdb:6YOV|reactome:R-HSA-2892245|reactome:R-HSA-2892247|reactome:R-HSA-3769402|reactome:R-HSA-452723|reactome:R-HSA-6785807|reactome:R-HSA-8986944 refseq:NP_001545.2|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0030501"(positive regulation of bone mineralization)|go:"GO:0030513"(positive regulation of BMP signaling pathway)|go:"GO:0031012"(extracellular matrix)|go:"GO:0033690"(positive regulation of osteoblast proliferation)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043280"(positive regulation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0044319"(wound healing, spreading of cells)|go:"GO:0045669"(positive regulation of osteoblast differentiation)|go:"GO:0045860"(positive regulation of protein kinase activity)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0050840"(extracellular matrix binding)|go:"GO:0060413"(atrial septum morphogenesis)|go:"GO:0060548"(negative regulation of cell death)|go:"GO:0060591"(chondroblast differentiation)|go:"GO:0060710"(chorio-allantoic fusion)|go:"GO:0060716"(labyrinthine layer blood vessel development)|go:"GO:0061036"(positive regulation of cartilage development)|go:"GO:0062023"(collagen-containing extracellular matrix)|go:"GO:0070372"(regulation of ERK1 and ERK2 cascade)|go:"GO:0072593"(reactive oxygen species metabolic process)|go:"GO:2000304"(positive regulation of ceramide biosynthetic process)|interpro:IPR000867(Insulin-like growth factor-binding protein, IGFBP)|interpro:IPR000884(Thrombospondin, type I)|interpro:IPR001007(von Willebrand factor, type C)|interpro:IPR006207(Cystine knot, C-terminal)|interpro:IPR006208(Cystine knot)|interpro:IPR009030(Growth factor, receptor)|interpro:IPR012395(IGFBP-related, CNN)|interpro:IPR017891|interpro:IPR036383|interpro:IPR043973|mint:O00622|rcsb pdb:4D0Z|rcsb pdb:4D11|reactome:R-HSA-381426|reactome:R-HSA-8957275|go:"GO:0030198"(extracellular matrix organization)|ensembl:ENSG00000142871(gene)|ensembl:ENST00000451137(transcript)|go:"GO:0001649"(osteoblast differentiation)|go:"GO:0001934"(positive regulation of protein phosphorylation)|go:"GO:0002041"(intussusceptive angiogenesis)|go:"GO:0003181"(atrioventricular valve morphogenesis)|go:"GO:0003278"(apoptotic process involved in heart morphogenesis)|go:"GO:0003281"(ventricular septum development)|go:"GO:0005178"(integrin binding)|go:"GO:0005520"(insulin-like growth factor binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005788"(endoplasmic reticulum lumen)|go:"GO:0006935"(chemotaxis)|go:"GO:0007155"(cell adhesion)|go:"GO:0007165"(signal transduction)|go:"GO:0008201"(heparin binding)|go:"GO:0010518"(positive regulation of phospholipase activity)|go:"GO:0010811"(positive regulation of cell-substrate adhesion) go:"GO:0005634"(nucleus) - - figure legend:ST3 F2C|comment:proteins that were enriched in the induced sample more than 6-fold|dataset:Brain Disease - Neurological Diseases & Disorders|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-daoy)|taxid:9606(Homo sapiens DAOY cerebellar medulloblastoma cell line) - 2020/12/29 2020/12/29 rogid:cn8gYfKDpQc8J2ygnqny32sIyyU9606 rogid:zjqBcViT2Kyh+41SJeOu/rcJqSk9606 rigid:Cnhili6Os5i+9KsmWx3iqclZGC0 false tandem tag:n-n - - - psi-mi:"MI:0658"(multidimensional protein identification technology) psi-mi:"MI:0658"(multidimensional protein identification technology) uniprotkb:P48431 uniprotkb:Q8IXK0 intact:EBI-6124081|uniprotkb:Q14537|ensembl:ENSP00000323588 intact:EBI-713786|uniprotkb:Q8N306|uniprotkb:Q8TAG8|uniprotkb:A1L4Q1|uniprotkb:Q2TAL3|uniprotkb:Q5T0C1|uniprotkb:Q6NUJ6|uniprotkb:Q6ZQR1|uniprotkb:Q96BL4|uniprotkb:Q9Y4Y7|ensembl:ENSP00000257118|uniprotkb:D3DPR2|uniprotkb:A8KA40 psi-mi:sox2_human(display_long)|uniprotkb:SOX2(gene name)|psi-mi:SOX2(display_short) psi-mi:phc2_human(display_long)|uniprotkb:Early development regulatory protein 2(gene name synonym)|uniprotkb:PHC2(gene name)|psi-mi:PHC2(display_short)|uniprotkb:EDR2(gene name synonym)|uniprotkb:PH2(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Cox et al. (2012) pubmed:23667531|imex:IM-28599 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-26574478|imex:IM-28599-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_003097.1|dip:DIP-59913N|ensembl:ENSG00000181449(gene)|ensembl:ENST00000325404(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001649"(osteoblast differentiation)|go:"GO:0001654"(eye development)|go:"GO:0001714"(endodermal cell fate specification)|go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006325"(chromatin organization)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0009611"(response to wounding)|go:"GO:0009653"(anatomical structure morphogenesis)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0021781"(glial cell fate commitment)|go:"GO:0021983"(pituitary gland development)|go:"GO:0021984"(adenohypophysis development)|go:"GO:0022409"(positive regulation of cell-cell adhesion)|go:"GO:0030154"(cell differentiation)|go:"GO:0030900"(forebrain development)|go:"GO:0035019"(somatic stem cell population maintenance)|go:"GO:0035198"(miRNA binding)|go:"GO:0042246"(tissue regeneration)|go:"GO:0043281"(regulation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0043410"(positive regulation of MAPK cascade)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045165"(cell fate commitment)|go:"GO:0045597"(positive regulation of cell differentiation)|go:"GO:0045665"(negative regulation of neuron differentiation)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048839"(inner ear development)|go:"GO:0050680"(negative regulation of epithelial cell proliferation)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0070848"(response to growth factor)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:0097150"(neuronal stem cell population maintenance)|interpro:IPR009071(High mobility group box, HMG)|interpro:IPR022097|interpro:IPR032643|interpro:IPR036910|mint:P48431|rcsb pdb:1O4X|rcsb pdb:2LE4|rcsb pdb:6T7B|rcsb pdb:6T90|rcsb pdb:6WX7|rcsb pdb:6WX8|rcsb pdb:6WX9|rcsb pdb:6YOV|reactome:R-HSA-2892245|reactome:R-HSA-2892247|reactome:R-HSA-3769402|reactome:R-HSA-452723|reactome:R-HSA-6785807|reactome:R-HSA-8986944 interpro:IPR038603|mint:Q8IXK0|reactome:R-HSA-2559580|reactome:R-HSA-3108214|reactome:R-HSA-3899300|reactome:R-HSA-4551638|reactome:R-HSA-4570464|reactome:R-HSA-4655427|reactome:R-HSA-8939243|reactome:R-HSA-8943724|interpro:IPR013761(Sterile alpha motif-type)|ensembl:ENSG00000134686(gene)|ensembl:ENST00000257118(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0008270"(zinc ion binding)|go:"GO:0031519"(PcG protein complex)|go:"GO:0035102"(PRC1 complex)|go:"GO:0042393"(histone binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|interpro:IPR001660(Sterile alpha motif SAM)|interpro:IPR012313(Zinc finger, FCS-type)|refseq:NP_004418.2|refseq:NP_932157.1|refseq:XP_016856005.1|refseq:XP_016856006.1|refseq:XP_016856007.1|refseq:XP_005270627.1|dip:DIP-34464N go:"GO:0005634"(nucleus) - - figure legend:ST3 F2C|comment:proteins that were enriched in the induced sample more than 6-fold|dataset:Brain Disease - Neurological Diseases & Disorders|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-daoy)|taxid:9606(Homo sapiens DAOY cerebellar medulloblastoma cell line) - 2020/12/29 2020/12/29 rogid:cn8gYfKDpQc8J2ygnqny32sIyyU9606 rogid:7si/KU2tHoxviuCr70ncQERDWmY9606 rigid:Cnhili6Os5i+9KsmWx3iqclZGC0 false tandem tag:n-n - - - psi-mi:"MI:0658"(multidimensional protein identification technology) psi-mi:"MI:0658"(multidimensional protein identification technology) uniprotkb:P48431 uniprotkb:P46060 intact:EBI-6124081|uniprotkb:Q14537|ensembl:ENSP00000323588 intact:EBI-396091|uniprotkb:Q96JJ2|ensembl:ENSP00000401470|ensembl:ENSP00000348577|ensembl:ENSP00000385866 psi-mi:sox2_human(display_long)|uniprotkb:SOX2(gene name)|psi-mi:SOX2(display_short) psi-mi:ragp1_human(display_long)|uniprotkb:RANGAP1(gene name)|psi-mi:RANGAP1(display_short)|uniprotkb:KIAA1835(gene name synonym)|uniprotkb:SD(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Cox et al. (2012) pubmed:23667531|imex:IM-28599 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-26574478|imex:IM-28599-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_003097.1|dip:DIP-59913N|ensembl:ENSG00000181449(gene)|ensembl:ENST00000325404(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001649"(osteoblast differentiation)|go:"GO:0001654"(eye development)|go:"GO:0001714"(endodermal cell fate specification)|go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006325"(chromatin organization)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0009611"(response to wounding)|go:"GO:0009653"(anatomical structure morphogenesis)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0021781"(glial cell fate commitment)|go:"GO:0021983"(pituitary gland development)|go:"GO:0021984"(adenohypophysis development)|go:"GO:0022409"(positive regulation of cell-cell adhesion)|go:"GO:0030154"(cell differentiation)|go:"GO:0030900"(forebrain development)|go:"GO:0035019"(somatic stem cell population maintenance)|go:"GO:0035198"(miRNA binding)|go:"GO:0042246"(tissue regeneration)|go:"GO:0043281"(regulation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0043410"(positive regulation of MAPK cascade)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045165"(cell fate commitment)|go:"GO:0045597"(positive regulation of cell differentiation)|go:"GO:0045665"(negative regulation of neuron differentiation)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048839"(inner ear development)|go:"GO:0050680"(negative regulation of epithelial cell proliferation)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0070848"(response to growth factor)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:0097150"(neuronal stem cell population maintenance)|interpro:IPR009071(High mobility group box, HMG)|interpro:IPR022097|interpro:IPR032643|interpro:IPR036910|mint:P48431|rcsb pdb:1O4X|rcsb pdb:2LE4|rcsb pdb:6T7B|rcsb pdb:6T90|rcsb pdb:6WX7|rcsb pdb:6WX8|rcsb pdb:6WX9|rcsb pdb:6YOV|reactome:R-HSA-2892245|reactome:R-HSA-2892247|reactome:R-HSA-3769402|reactome:R-HSA-452723|reactome:R-HSA-6785807|reactome:R-HSA-8986944 refseq:NP_002874.1|ensembl:ENST00000356244(transcript)|ensembl:ENST00000405486(transcript)|ensembl:ENST00000455915(transcript)|go:"GO:0000776"(kinetochore)|go:"GO:0003723"(RNA binding)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005643"(nuclear pore)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0007165"(signal transduction)|go:"GO:0016235"(aggresome)|go:"GO:0030425"(dendrite)|go:"GO:0031267"(small GTPase binding)|go:"GO:0031625"(ubiquitin protein ligase binding)|refseq:XP_011528596.1|refseq:XP_011528597.1|refseq:NP_001304859.1|go:"GO:0031965"(nuclear membrane)|interpro:IPR009109(Ran-GTPase activating protein 1, C-terminal)|interpro:IPR032675|interpro:IPR036720|mint:P46060|rcsb pdb:1Z5S|rcsb pdb:2GRN|rcsb pdb:2GRO|rcsb pdb:2GRP|rcsb pdb:2GRQ|rcsb pdb:2GRR|rcsb pdb:2IO2|rcsb pdb:2IO3|rcsb pdb:2IY0|rcsb pdb:3UIN|rcsb pdb:3UIO|rcsb pdb:3UIP|rcsb pdb:5D2M|reactome:R-HSA-141444|reactome:R-HSA-165054|reactome:R-HSA-2467813|interpro:IPR001611(Leucine-rich repeat)|reactome:R-HSA-2500257|reactome:R-HSA-3108232|go:"GO:0044614"(nuclear pore cytoplasmic filaments)|go:"GO:0045296"(cadherin binding)|go:"GO:0046826"(negative regulation of protein export from nucleus)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0048678"(response to axon injury)|go:"GO:0072686"(mitotic spindle)|go:"GO:0090630"(activation of GTPase activity)|go:"GO:1904115"(axon cytoplasm)|go:"GO:1904117"(cellular response to vasopressin)|go:"GO:1990723"(cytoplasmic periphery of the nuclear pore complex)|go:"GO:0043231"(intracellular membrane-bounded organelle)|ensembl:ENSG00000100401(gene)|refseq:XP_006724352.1|reactome:R-HSA-4615885|refseq:NP_001265580.1|reactome:R-HSA-68877|reactome:R-HSA-9615933|reactome:R-HSA-9648025|reactome:R-HSA-5663220|refseq:XP_016884382.1|refseq:XP_016884383.1|refseq:XP_016884384.1|refseq:XP_016884385.1|refseq:XP_016884386.1|dip:DIP-29079N go:"GO:0005634"(nucleus) - - figure legend:ST3 F2C|comment:proteins that were enriched in the induced sample more than 6-fold|dataset:Brain Disease - Neurological Diseases & Disorders|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-daoy)|taxid:9606(Homo sapiens DAOY cerebellar medulloblastoma cell line) - 2020/12/29 2020/12/29 rogid:cn8gYfKDpQc8J2ygnqny32sIyyU9606 rogid:pUpd+7p5CeAKaRGLo/bXTeiwjiM9606 rigid:Cnhili6Os5i+9KsmWx3iqclZGC0 false tandem tag:n-n - - - psi-mi:"MI:0658"(multidimensional protein identification technology) psi-mi:"MI:0658"(multidimensional protein identification technology) uniprotkb:P48431 uniprotkb:Q9BRA0 intact:EBI-6124081|uniprotkb:Q14537|ensembl:ENSP00000323588 intact:EBI-9106509|uniprotkb:Q8N4M0|ensembl:ENSP00000460172 psi-mi:sox2_human(display_long)|uniprotkb:SOX2(gene name)|psi-mi:SOX2(display_short) psi-mi:lsmd1_human(display_long)|uniprotkb:NAA38(gene name)|psi-mi:NAA38(display_short)|uniprotkb:LSM domain-containing protein 1(gene name synonym)|uniprotkb:LSMD1(gene name synonym)|uniprotkb:MAK31(gene name synonym)|uniprotkb:PFAAP2(gene name synonym)|uniprotkb:Phosphonoformate immuno-associated protein 2(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Cox et al. (2012) pubmed:23667531|imex:IM-28599 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-26574478|imex:IM-28599-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_003097.1|dip:DIP-59913N|ensembl:ENSG00000181449(gene)|ensembl:ENST00000325404(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001649"(osteoblast differentiation)|go:"GO:0001654"(eye development)|go:"GO:0001714"(endodermal cell fate specification)|go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006325"(chromatin organization)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0009611"(response to wounding)|go:"GO:0009653"(anatomical structure morphogenesis)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0021781"(glial cell fate commitment)|go:"GO:0021983"(pituitary gland development)|go:"GO:0021984"(adenohypophysis development)|go:"GO:0022409"(positive regulation of cell-cell adhesion)|go:"GO:0030154"(cell differentiation)|go:"GO:0030900"(forebrain development)|go:"GO:0035019"(somatic stem cell population maintenance)|go:"GO:0035198"(miRNA binding)|go:"GO:0042246"(tissue regeneration)|go:"GO:0043281"(regulation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0043410"(positive regulation of MAPK cascade)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045165"(cell fate commitment)|go:"GO:0045597"(positive regulation of cell differentiation)|go:"GO:0045665"(negative regulation of neuron differentiation)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048839"(inner ear development)|go:"GO:0050680"(negative regulation of epithelial cell proliferation)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0070848"(response to growth factor)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:0097150"(neuronal stem cell population maintenance)|interpro:IPR009071(High mobility group box, HMG)|interpro:IPR022097|interpro:IPR032643|interpro:IPR036910|mint:P48431|rcsb pdb:1O4X|rcsb pdb:2LE4|rcsb pdb:6T7B|rcsb pdb:6T90|rcsb pdb:6WX7|rcsb pdb:6WX8|rcsb pdb:6WX9|rcsb pdb:6YOV|reactome:R-HSA-2892245|reactome:R-HSA-2892247|reactome:R-HSA-3769402|reactome:R-HSA-452723|reactome:R-HSA-6785807|reactome:R-HSA-8986944 refseq:NP_001307854.1|refseq:NP_115732.2|ensembl:ENSG00000183011(gene)|ensembl:ENST00000575771(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0031417"(NatC complex)|go:"GO:0043066"(negative regulation of apoptotic process)|interpro:IPR001163(Like-Sm ribonucleoprotein, core)|interpro:IPR010920(Like-Sm ribonucleoprotein-related, core)|interpro:IPR034110|mint:Q9BRA0|reactome:R-HSA-6811440 go:"GO:0005634"(nucleus) - - figure legend:ST3 F2C|comment:proteins that were enriched in the induced sample more than 6-fold|dataset:Brain Disease - Neurological Diseases & Disorders|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-daoy)|taxid:9606(Homo sapiens DAOY cerebellar medulloblastoma cell line) - 2020/12/29 2020/12/29 rogid:cn8gYfKDpQc8J2ygnqny32sIyyU9606 rogid:DOp1Vv0k0UnbIc6e6O5KGDLVjLM9606 rigid:Cnhili6Os5i+9KsmWx3iqclZGC0 false tandem tag:n-n - - - psi-mi:"MI:0658"(multidimensional protein identification technology) psi-mi:"MI:0658"(multidimensional protein identification technology) uniprotkb:P48431 uniprotkb:Q9UHB9 intact:EBI-6124081|uniprotkb:Q14537|ensembl:ENSP00000323588 intact:EBI-1048560|uniprotkb:Q8NCJ4|uniprotkb:Q8WUK2|uniprotkb:B3KUU5|uniprotkb:B3KWY7|uniprotkb:G3V1U4|ensembl:ENSP00000312066 psi-mi:sox2_human(display_long)|uniprotkb:SOX2(gene name)|psi-mi:SOX2(display_short) psi-mi:srp68_human(display_long)|uniprotkb:SRP68(gene name)|psi-mi:SRP68(display_short)|uniprotkb:Signal recognition particle 68 kDa protein(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Cox et al. (2012) pubmed:23667531|imex:IM-28599 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-26574478|imex:IM-28599-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_003097.1|dip:DIP-59913N|ensembl:ENSG00000181449(gene)|ensembl:ENST00000325404(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001649"(osteoblast differentiation)|go:"GO:0001654"(eye development)|go:"GO:0001714"(endodermal cell fate specification)|go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006325"(chromatin organization)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0009611"(response to wounding)|go:"GO:0009653"(anatomical structure morphogenesis)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0021781"(glial cell fate commitment)|go:"GO:0021983"(pituitary gland development)|go:"GO:0021984"(adenohypophysis development)|go:"GO:0022409"(positive regulation of cell-cell adhesion)|go:"GO:0030154"(cell differentiation)|go:"GO:0030900"(forebrain development)|go:"GO:0035019"(somatic stem cell population maintenance)|go:"GO:0035198"(miRNA binding)|go:"GO:0042246"(tissue regeneration)|go:"GO:0043281"(regulation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0043410"(positive regulation of MAPK cascade)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045165"(cell fate commitment)|go:"GO:0045597"(positive regulation of cell differentiation)|go:"GO:0045665"(negative regulation of neuron differentiation)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048839"(inner ear development)|go:"GO:0050680"(negative regulation of epithelial cell proliferation)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0070848"(response to growth factor)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:0097150"(neuronal stem cell population maintenance)|interpro:IPR009071(High mobility group box, HMG)|interpro:IPR022097|interpro:IPR032643|interpro:IPR036910|mint:P48431|rcsb pdb:1O4X|rcsb pdb:2LE4|rcsb pdb:6T7B|rcsb pdb:6T90|rcsb pdb:6WX7|rcsb pdb:6WX8|rcsb pdb:6WX9|rcsb pdb:6YOV|reactome:R-HSA-2892245|reactome:R-HSA-2892247|reactome:R-HSA-3769402|reactome:R-HSA-452723|reactome:R-HSA-6785807|reactome:R-HSA-8986944 refseq:NP_001247431.1|refseq:NP_001247432.1|refseq:NP_055045.2|interpro:IPR026258|interpro:IPR034652|interpro:IPR038253|mint:Q9UHB9|rcsb pdb:4P3E|rcsb pdb:4P3F|rcsb pdb:5M72|rcsb pdb:5M73|rcsb pdb:5WRV|rcsb pdb:7NFX|reactome:R-HSA-1799339|ensembl:ENSG00000167881(gene)|ensembl:ENST00000307877(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0005047"(signal recognition particle binding)|go:"GO:0005730"(nucleolus)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005786"(signal recognition particle, endoplasmic reticulum targeting)|go:"GO:0005829"(cytosol)|go:"GO:0005840"(ribosome)|go:"GO:0005925"(focal adhesion)|go:"GO:0006614"(SRP-dependent cotranslational protein targeting to membrane)|go:"GO:0008312"(7S RNA binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030942"(endoplasmic reticulum signal peptide binding)|go:"GO:0042493"|go:"GO:0048500"(signal recognition particle)|dip:DIP-50905N go:"GO:0005634"(nucleus) - - figure legend:ST3 F2C|comment:proteins that were enriched in the induced sample more than 6-fold|dataset:Brain Disease - Neurological Diseases & Disorders|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-daoy)|taxid:9606(Homo sapiens DAOY cerebellar medulloblastoma cell line) - 2020/12/29 2020/12/29 rogid:cn8gYfKDpQc8J2ygnqny32sIyyU9606 rogid:8WwEMUV+QzJGJ6G7xufvSibYTSY9606 rigid:Cnhili6Os5i+9KsmWx3iqclZGC0 false tandem tag:n-n - - - psi-mi:"MI:0658"(multidimensional protein identification technology) psi-mi:"MI:0658"(multidimensional protein identification technology) uniprotkb:P48431 uniprotkb:Q9UJX3 intact:EBI-6124081|uniprotkb:Q14537|ensembl:ENSP00000323588 intact:EBI-1384164|uniprotkb:Q96AC4|uniprotkb:Q96GF4|uniprotkb:Q9BU24|uniprotkb:Q9NT16|ensembl:ENSP00000394394|ensembl:ENSP00000402314 psi-mi:sox2_human(display_long)|uniprotkb:SOX2(gene name)|psi-mi:SOX2(display_short) psi-mi:apc7_human(display_long)|uniprotkb:ANAPC7(gene name)|psi-mi:ANAPC7(display_short)|uniprotkb:APC7(gene name synonym)|uniprotkb:Cyclosome subunit 7(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Cox et al. (2012) pubmed:23667531|imex:IM-28599 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-26574478|imex:IM-28599-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_003097.1|dip:DIP-59913N|ensembl:ENSG00000181449(gene)|ensembl:ENST00000325404(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001649"(osteoblast differentiation)|go:"GO:0001654"(eye development)|go:"GO:0001714"(endodermal cell fate specification)|go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006325"(chromatin organization)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0009611"(response to wounding)|go:"GO:0009653"(anatomical structure morphogenesis)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0021781"(glial cell fate commitment)|go:"GO:0021983"(pituitary gland development)|go:"GO:0021984"(adenohypophysis development)|go:"GO:0022409"(positive regulation of cell-cell adhesion)|go:"GO:0030154"(cell differentiation)|go:"GO:0030900"(forebrain development)|go:"GO:0035019"(somatic stem cell population maintenance)|go:"GO:0035198"(miRNA binding)|go:"GO:0042246"(tissue regeneration)|go:"GO:0043281"(regulation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0043410"(positive regulation of MAPK cascade)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045165"(cell fate commitment)|go:"GO:0045597"(positive regulation of cell differentiation)|go:"GO:0045665"(negative regulation of neuron differentiation)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048839"(inner ear development)|go:"GO:0050680"(negative regulation of epithelial cell proliferation)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0070848"(response to growth factor)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:0097150"(neuronal stem cell population maintenance)|interpro:IPR009071(High mobility group box, HMG)|interpro:IPR022097|interpro:IPR032643|interpro:IPR036910|mint:P48431|rcsb pdb:1O4X|rcsb pdb:2LE4|rcsb pdb:6T7B|rcsb pdb:6T90|rcsb pdb:6WX7|rcsb pdb:6WX8|rcsb pdb:6WX9|rcsb pdb:6YOV|reactome:R-HSA-2892245|reactome:R-HSA-2892247|reactome:R-HSA-3769402|reactome:R-HSA-452723|reactome:R-HSA-6785807|reactome:R-HSA-8986944 refseq:NP_001131136.1|refseq:NP_057322.2|dip:DIP-39765N|ensembl:ENSG00000196510(gene)|ensembl:ENST00000450008(transcript)|ensembl:ENST00000455511(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005680"(anaphase-promoting complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0005819"(spindle)|go:"GO:0005829"(cytosol)|go:"GO:0007091"(metaphase/anaphase transition of mitotic cell cycle)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0019903"(protein phosphatase binding)|go:"GO:0031145"(anaphase-promoting complex-dependent catabolic process)|go:"GO:0045842"(positive regulation of mitotic metaphase/anaphase transition)|go:"GO:0051301"(cell division)|go:"GO:0070979"(protein K11-linked ubiquitination)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR019734|mint:Q9UJX3|rcsb pdb:3FFL|rcsb pdb:4UI9|rcsb pdb:5A31|rcsb pdb:5G04|rcsb pdb:5G05|rcsb pdb:5KHR|rcsb pdb:5KHU|rcsb pdb:5L9T|rcsb pdb:5L9U|rcsb pdb:5LCW|rcsb pdb:6Q6G|rcsb pdb:6Q6H|rcsb pdb:6TLJ|rcsb pdb:6TM5|rcsb pdb:6TNT|reactome:R-HSA-141430|reactome:R-HSA-174048|reactome:R-HSA-174084|reactome:R-HSA-174154|reactome:R-HSA-174178|reactome:R-HSA-174184|reactome:R-HSA-176407|reactome:R-HSA-176408|reactome:R-HSA-176409|reactome:R-HSA-176412|reactome:R-HSA-179409|reactome:R-HSA-2467813|reactome:R-HSA-2559582|reactome:R-HSA-69017|reactome:R-HSA-8853884|reactome:R-HSA-9687136|reactome:R-HSA-983168 go:"GO:0005634"(nucleus) - - figure legend:ST3 F2C|comment:proteins that were enriched in the induced sample more than 6-fold|dataset:Brain Disease - Neurological Diseases & Disorders|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-daoy)|taxid:9606(Homo sapiens DAOY cerebellar medulloblastoma cell line) - 2020/12/29 2020/12/29 rogid:cn8gYfKDpQc8J2ygnqny32sIyyU9606 rogid:2q+llvuIzK2MOWjPuOUxmyN782E9606 rigid:Cnhili6Os5i+9KsmWx3iqclZGC0 false tandem tag:n-n - - - psi-mi:"MI:0658"(multidimensional protein identification technology) psi-mi:"MI:0658"(multidimensional protein identification technology) uniprotkb:P48431 uniprotkb:Q92616 intact:EBI-6124081|uniprotkb:Q14537|ensembl:ENSP00000323588 intact:EBI-356221|ensembl:ENSP00000300648|uniprotkb:O95001|uniprotkb:O95651|uniprotkb:Q6P2S3|uniprotkb:Q86X65|uniprotkb:Q8N5I5|uniprotkb:Q8WU80|uniprotkb:Q99736|uniprotkb:Q9UE60|uniprotkb:A8KAY1|intact:EBI-1058692 psi-mi:sox2_human(display_long)|uniprotkb:SOX2(gene name)|psi-mi:SOX2(display_short) psi-mi:gcn1_human(display_long)|uniprotkb:GCN1(gene name)|psi-mi:GCN1(display_short)|uniprotkb:GCN1 eIF-2-alpha kinase activator homolog(gene name synonym)|uniprotkb:GCN1-like protein 1(gene name synonym)|uniprotkb:GCN1L1(gene name synonym)|uniprotkb:General control of amino-acid synthesis 1-like protein 1(gene name synonym)|uniprotkb:KIAA0219(gene name synonym)|uniprotkb:Translational activator GCN1(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Cox et al. (2012) pubmed:23667531|imex:IM-28599 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-26574478|imex:IM-28599-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_003097.1|dip:DIP-59913N|ensembl:ENSG00000181449(gene)|ensembl:ENST00000325404(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001649"(osteoblast differentiation)|go:"GO:0001654"(eye development)|go:"GO:0001714"(endodermal cell fate specification)|go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006325"(chromatin organization)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0009611"(response to wounding)|go:"GO:0009653"(anatomical structure morphogenesis)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0021781"(glial cell fate commitment)|go:"GO:0021983"(pituitary gland development)|go:"GO:0021984"(adenohypophysis development)|go:"GO:0022409"(positive regulation of cell-cell adhesion)|go:"GO:0030154"(cell differentiation)|go:"GO:0030900"(forebrain development)|go:"GO:0035019"(somatic stem cell population maintenance)|go:"GO:0035198"(miRNA binding)|go:"GO:0042246"(tissue regeneration)|go:"GO:0043281"(regulation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0043410"(positive regulation of MAPK cascade)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045165"(cell fate commitment)|go:"GO:0045597"(positive regulation of cell differentiation)|go:"GO:0045665"(negative regulation of neuron differentiation)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048839"(inner ear development)|go:"GO:0050680"(negative regulation of epithelial cell proliferation)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0070848"(response to growth factor)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:0097150"(neuronal stem cell population maintenance)|interpro:IPR009071(High mobility group box, HMG)|interpro:IPR022097|interpro:IPR032643|interpro:IPR036910|mint:P48431|rcsb pdb:1O4X|rcsb pdb:2LE4|rcsb pdb:6T7B|rcsb pdb:6T90|rcsb pdb:6WX7|rcsb pdb:6WX8|rcsb pdb:6WX9|rcsb pdb:6YOV|reactome:R-HSA-2892245|reactome:R-HSA-2892247|reactome:R-HSA-3769402|reactome:R-HSA-452723|reactome:R-HSA-6785807|reactome:R-HSA-8986944 ensembl:ENSG00000089154(gene)|ensembl:ENST00000300648(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005840"(ribosome)|go:"GO:0008135"(translation factor activity, RNA binding)|go:"GO:0016020"(membrane)|go:"GO:0019887"(protein kinase regulator activity)|go:"GO:0019901"(protein kinase binding)|go:"GO:0033674"(positive regulation of kinase activity)|go:"GO:0034198"(cellular response to amino acid starvation)|go:"GO:0036003"(positive regulation of transcription from RNA polymerase II promoter in response to stress)|go:"GO:0043022"(ribosome binding)|go:"GO:0045296"(cadherin binding)|go:"GO:1990253"(cellular response to leucine starvation)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR021133|interpro:IPR033173|interpro:IPR034085|mint:Q92616|reactome:R-HSA-9633012|go:"GO:0005844"(polysome)|refseq:NP_006827.1 go:"GO:0005634"(nucleus) - - figure legend:ST3 F2C|comment:proteins that were enriched in the induced sample more than 6-fold|dataset:Brain Disease - Neurological Diseases & Disorders|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-daoy)|taxid:9606(Homo sapiens DAOY cerebellar medulloblastoma cell line) - 2020/12/29 2020/12/29 rogid:cn8gYfKDpQc8J2ygnqny32sIyyU9606 rogid:NtSEW6xjvCkUyb40cnk0JdL5PcA9606 rigid:Cnhili6Os5i+9KsmWx3iqclZGC0 false tandem tag:n-n - - - psi-mi:"MI:0658"(multidimensional protein identification technology) psi-mi:"MI:0658"(multidimensional protein identification technology) uniprotkb:P48431 uniprotkb:O95373 intact:EBI-6124081|uniprotkb:Q14537|ensembl:ENSP00000323588 intact:EBI-286735|uniprotkb:A6NNM5|uniprotkb:Q1RMF7|uniprotkb:Q9H177|uniprotkb:Q9NTE3|uniprotkb:B2R786|intact:EBI-28976968|ensembl:ENSP00000369042 psi-mi:sox2_human(display_long)|uniprotkb:SOX2(gene name)|psi-mi:SOX2(display_short) psi-mi:ipo7_human(display_long)|uniprotkb:Ran-binding protein 7(gene name synonym)|uniprotkb:IPO7(gene name)|psi-mi:IPO7(display_short)|uniprotkb:RANBP7(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Cox et al. (2012) pubmed:23667531|imex:IM-28599 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-26574478|imex:IM-28599-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_003097.1|dip:DIP-59913N|ensembl:ENSG00000181449(gene)|ensembl:ENST00000325404(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001649"(osteoblast differentiation)|go:"GO:0001654"(eye development)|go:"GO:0001714"(endodermal cell fate specification)|go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006325"(chromatin organization)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0009611"(response to wounding)|go:"GO:0009653"(anatomical structure morphogenesis)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0021781"(glial cell fate commitment)|go:"GO:0021983"(pituitary gland development)|go:"GO:0021984"(adenohypophysis development)|go:"GO:0022409"(positive regulation of cell-cell adhesion)|go:"GO:0030154"(cell differentiation)|go:"GO:0030900"(forebrain development)|go:"GO:0035019"(somatic stem cell population maintenance)|go:"GO:0035198"(miRNA binding)|go:"GO:0042246"(tissue regeneration)|go:"GO:0043281"(regulation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0043410"(positive regulation of MAPK cascade)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045165"(cell fate commitment)|go:"GO:0045597"(positive regulation of cell differentiation)|go:"GO:0045665"(negative regulation of neuron differentiation)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048839"(inner ear development)|go:"GO:0050680"(negative regulation of epithelial cell proliferation)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0070848"(response to growth factor)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:0097150"(neuronal stem cell population maintenance)|interpro:IPR009071(High mobility group box, HMG)|interpro:IPR022097|interpro:IPR032643|interpro:IPR036910|mint:P48431|rcsb pdb:1O4X|rcsb pdb:2LE4|rcsb pdb:6T7B|rcsb pdb:6T90|rcsb pdb:6WX7|rcsb pdb:6WX8|rcsb pdb:6WX9|rcsb pdb:6YOV|reactome:R-HSA-2892245|reactome:R-HSA-2892247|reactome:R-HSA-3769402|reactome:R-HSA-452723|reactome:R-HSA-6785807|reactome:R-HSA-8986944 ensembl:ENSP00000369042|refseq:NP_006382.1|dip:DIP-32574N|ensembl:ENSG00000205339(gene)|ensembl:ENST00000379719(transcript)|go:"GO:0005215"(transporter activity)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005643"(nuclear pore)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0007165"(signal transduction)|go:"GO:0016020"(membrane)|go:"GO:0030695"(GTPase regulator activity)|go:"GO:0031267"(small GTPase binding)|go:"GO:0042393"(histone binding)|go:"GO:0045087"(innate immune response)|go:"GO:0045736"(negative regulation of cyclin-dependent protein serine/threonine kinase activity)|go:"GO:0046332"(SMAD binding)|interpro:IPR001494(Importin-beta, N-terminal)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR013713(Exportin, Cse1-like)|interpro:IPR016024(Armadillo-type fold)|mint:O95373 go:"GO:0005634"(nucleus) - - figure legend:ST3 F2C|comment:proteins that were enriched in the induced sample more than 6-fold|dataset:Brain Disease - Neurological Diseases & Disorders|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-daoy)|taxid:9606(Homo sapiens DAOY cerebellar medulloblastoma cell line) - 2020/12/29 2020/12/29 rogid:cn8gYfKDpQc8J2ygnqny32sIyyU9606 rogid:aaTn9E3/dTUETnNBYr38fk4ZtDo9606 rigid:Cnhili6Os5i+9KsmWx3iqclZGC0 false tandem tag:n-n - - - psi-mi:"MI:0658"(multidimensional protein identification technology) psi-mi:"MI:0658"(multidimensional protein identification technology) uniprotkb:P48431 uniprotkb:O60732 intact:EBI-6124081|uniprotkb:Q14537|ensembl:ENSP00000323588 intact:EBI-1188463|uniprotkb:O75451|uniprotkb:Q8TCV4|uniprotkb:A0PK03|ensembl:ENSP00000285879 psi-mi:sox2_human(display_long)|uniprotkb:SOX2(gene name)|psi-mi:SOX2(display_short) psi-mi:magc1_human(display_long)|uniprotkb:MAGE-C1 antigen(gene name synonym)|uniprotkb:Cancer/testis antigen 7.1(gene name synonym)|uniprotkb:MAGEC1(gene name)|psi-mi:MAGEC1(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Cox et al. (2012) pubmed:23667531|imex:IM-28599 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-26574478|imex:IM-28599-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_003097.1|dip:DIP-59913N|ensembl:ENSG00000181449(gene)|ensembl:ENST00000325404(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001649"(osteoblast differentiation)|go:"GO:0001654"(eye development)|go:"GO:0001714"(endodermal cell fate specification)|go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006325"(chromatin organization)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0009611"(response to wounding)|go:"GO:0009653"(anatomical structure morphogenesis)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0021781"(glial cell fate commitment)|go:"GO:0021983"(pituitary gland development)|go:"GO:0021984"(adenohypophysis development)|go:"GO:0022409"(positive regulation of cell-cell adhesion)|go:"GO:0030154"(cell differentiation)|go:"GO:0030900"(forebrain development)|go:"GO:0035019"(somatic stem cell population maintenance)|go:"GO:0035198"(miRNA binding)|go:"GO:0042246"(tissue regeneration)|go:"GO:0043281"(regulation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0043410"(positive regulation of MAPK cascade)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045165"(cell fate commitment)|go:"GO:0045597"(positive regulation of cell differentiation)|go:"GO:0045665"(negative regulation of neuron differentiation)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048839"(inner ear development)|go:"GO:0050680"(negative regulation of epithelial cell proliferation)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0070848"(response to growth factor)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:0097150"(neuronal stem cell population maintenance)|interpro:IPR009071(High mobility group box, HMG)|interpro:IPR022097|interpro:IPR032643|interpro:IPR036910|mint:P48431|rcsb pdb:1O4X|rcsb pdb:2LE4|rcsb pdb:6T7B|rcsb pdb:6T90|rcsb pdb:6WX7|rcsb pdb:6WX8|rcsb pdb:6WX9|rcsb pdb:6YOV|reactome:R-HSA-2892245|reactome:R-HSA-2892247|reactome:R-HSA-3769402|reactome:R-HSA-452723|reactome:R-HSA-6785807|reactome:R-HSA-8986944 refseq:NP_005453.2|refseq:XP_011529720.1|ensembl:ENSG00000155495(gene)|ensembl:ENST00000285879(transcript)|interpro:IPR002190(MAGE protein)|interpro:IPR037445|interpro:IPR041898|interpro:IPR041899|mint:O60732 go:"GO:0005634"(nucleus) - - figure legend:ST3 F2C|comment:proteins that were enriched in the induced sample more than 6-fold|dataset:Brain Disease - Neurological Diseases & Disorders|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-daoy)|taxid:9606(Homo sapiens DAOY cerebellar medulloblastoma cell line) - 2020/12/29 2020/12/29 rogid:cn8gYfKDpQc8J2ygnqny32sIyyU9606 rogid:AG0XGE9+dmavlRnHBTuP3RkfTgg9606 rigid:Cnhili6Os5i+9KsmWx3iqclZGC0 false tandem tag:n-n - - - psi-mi:"MI:0658"(multidimensional protein identification technology) psi-mi:"MI:0658"(multidimensional protein identification technology) uniprotkb:P48431 uniprotkb:P62699 intact:EBI-6124081|uniprotkb:Q14537|ensembl:ENSP00000323588 intact:EBI-11721624|uniprotkb:D6W568|uniprotkb:Q65Z97|uniprotkb:Q8R174|uniprotkb:Q9D6M1|uniprotkb:Q9UMX7|uniprotkb:Q9Y3C9|ensembl:ENSP00000261353|ensembl:ENSP00000368834|ensembl:ENSP00000368835|ensembl:ENSP00000383974|ensembl:ENSP00000385278 psi-mi:sox2_human(display_long)|uniprotkb:SOX2(gene name)|psi-mi:SOX2(display_short) psi-mi:ypel5_human(display_long)|uniprotkb:YPEL5(gene name)|psi-mi:YPEL5(display_short)|uniprotkb:CGI-127(orf name) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Cox et al. (2012) pubmed:23667531|imex:IM-28599 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-26574478|imex:IM-28599-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_003097.1|dip:DIP-59913N|ensembl:ENSG00000181449(gene)|ensembl:ENST00000325404(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001649"(osteoblast differentiation)|go:"GO:0001654"(eye development)|go:"GO:0001714"(endodermal cell fate specification)|go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006325"(chromatin organization)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0009611"(response to wounding)|go:"GO:0009653"(anatomical structure morphogenesis)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0021781"(glial cell fate commitment)|go:"GO:0021983"(pituitary gland development)|go:"GO:0021984"(adenohypophysis development)|go:"GO:0022409"(positive regulation of cell-cell adhesion)|go:"GO:0030154"(cell differentiation)|go:"GO:0030900"(forebrain development)|go:"GO:0035019"(somatic stem cell population maintenance)|go:"GO:0035198"(miRNA binding)|go:"GO:0042246"(tissue regeneration)|go:"GO:0043281"(regulation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0043410"(positive regulation of MAPK cascade)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045165"(cell fate commitment)|go:"GO:0045597"(positive regulation of cell differentiation)|go:"GO:0045665"(negative regulation of neuron differentiation)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048839"(inner ear development)|go:"GO:0050680"(negative regulation of epithelial cell proliferation)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0070848"(response to growth factor)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:0097150"(neuronal stem cell population maintenance)|interpro:IPR009071(High mobility group box, HMG)|interpro:IPR022097|interpro:IPR032643|interpro:IPR036910|mint:P48431|rcsb pdb:1O4X|rcsb pdb:2LE4|rcsb pdb:6T7B|rcsb pdb:6T90|rcsb pdb:6WX7|rcsb pdb:6WX8|rcsb pdb:6WX9|rcsb pdb:6YOV|reactome:R-HSA-2892245|reactome:R-HSA-2892247|reactome:R-HSA-3769402|reactome:R-HSA-452723|reactome:R-HSA-6785807|reactome:R-HSA-8986944 refseq:NP_001120871.1|refseq:NP_001120872.1|refseq:NP_001120873.1|refseq:NP_057145.1|ensembl:ENSG00000119801(gene)|ensembl:ENST00000261353(transcript)|ensembl:ENST00000379519(transcript)|ensembl:ENST00000379520(transcript)|ensembl:ENST00000402003(transcript)|ensembl:ENST00000402708(transcript)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0005576"(extracellular region)|go:"GO:0005634"(nucleus)|go:"GO:0005815"(microtubule organizing center)|go:"GO:0008283"(cell population proliferation)|go:"GO:0030496"(midbody)|go:"GO:0046872"(metal ion binding)|go:"GO:0097431"(mitotic spindle pole)|go:"GO:1904724"(tertiary granule lumen)|go:"GO:1904813"(ficolin-1-rich granule lumen)|interpro:IPR004910(Yippee-like protein)|interpro:IPR034751|interpro:IPR039058|mint:P62699|reactome:R-HSA-6798695|refseq:XP_016859807.1|refseq:XP_016859808.1|refseq:XP_016859809.1|refseq:XP_016859810.1|refseq:XP_016859811.1 go:"GO:0005634"(nucleus) - - figure legend:ST3 F2C|comment:proteins that were enriched in the induced sample more than 6-fold|dataset:Brain Disease - Neurological Diseases & Disorders|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-daoy)|taxid:9606(Homo sapiens DAOY cerebellar medulloblastoma cell line) - 2020/12/29 2020/12/29 rogid:cn8gYfKDpQc8J2ygnqny32sIyyU9606 rogid:ZpDZwTkWSDPONRLnApZ8fKl/NHk9606 rigid:Cnhili6Os5i+9KsmWx3iqclZGC0 false tandem tag:n-n - - - psi-mi:"MI:0658"(multidimensional protein identification technology) psi-mi:"MI:0658"(multidimensional protein identification technology) uniprotkb:P48431 uniprotkb:Q5SY16 intact:EBI-6124081|uniprotkb:Q14537|ensembl:ENSP00000323588 intact:EBI-1055462|uniprotkb:Q4VBY3|uniprotkb:Q6P472|uniprotkb:Q7L4D6|uniprotkb:Q96EE0|uniprotkb:Q9H5L4|uniprotkb:Q2NL84|ensembl:ENSP00000366934 psi-mi:sox2_human(display_long)|uniprotkb:SOX2(gene name)|psi-mi:SOX2(display_short) psi-mi:nol9_human(display_long)|uniprotkb:NOL9(gene name)|psi-mi:NOL9(display_short)|uniprotkb:Nucleolar protein 9(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Cox et al. (2012) pubmed:23667531|imex:IM-28599 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-26574478|imex:IM-28599-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_003097.1|dip:DIP-59913N|ensembl:ENSG00000181449(gene)|ensembl:ENST00000325404(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001649"(osteoblast differentiation)|go:"GO:0001654"(eye development)|go:"GO:0001714"(endodermal cell fate specification)|go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006325"(chromatin organization)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0009611"(response to wounding)|go:"GO:0009653"(anatomical structure morphogenesis)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0021781"(glial cell fate commitment)|go:"GO:0021983"(pituitary gland development)|go:"GO:0021984"(adenohypophysis development)|go:"GO:0022409"(positive regulation of cell-cell adhesion)|go:"GO:0030154"(cell differentiation)|go:"GO:0030900"(forebrain development)|go:"GO:0035019"(somatic stem cell population maintenance)|go:"GO:0035198"(miRNA binding)|go:"GO:0042246"(tissue regeneration)|go:"GO:0043281"(regulation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0043410"(positive regulation of MAPK cascade)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045165"(cell fate commitment)|go:"GO:0045597"(positive regulation of cell differentiation)|go:"GO:0045665"(negative regulation of neuron differentiation)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048839"(inner ear development)|go:"GO:0050680"(negative regulation of epithelial cell proliferation)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0070848"(response to growth factor)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:0097150"(neuronal stem cell population maintenance)|interpro:IPR009071(High mobility group box, HMG)|interpro:IPR022097|interpro:IPR032643|interpro:IPR036910|mint:P48431|rcsb pdb:1O4X|rcsb pdb:2LE4|rcsb pdb:6T7B|rcsb pdb:6T90|rcsb pdb:6WX7|rcsb pdb:6WX8|rcsb pdb:6WX9|rcsb pdb:6YOV|reactome:R-HSA-2892245|reactome:R-HSA-2892247|reactome:R-HSA-3769402|reactome:R-HSA-452723|reactome:R-HSA-6785807|reactome:R-HSA-8986944 refseq:NP_078930.3|refseq:XP_011540449.1|ensembl:ENST00000377705(transcript)|go:"GO:0000448"("cleavage in ITS2 between 5.8S rRNA and LSU-rRNA of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)")|go:"GO:0000460"(maturation of 5.8S rRNA)|go:"GO:0003723"(RNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0006396"(RNA processing)|go:"GO:0016020"(membrane)|go:"GO:0045111"(intermediate filament cytoskeleton)|go:"GO:0051731"(polynucleotide 5'-hydroxyl-kinase activity)|interpro:IPR027417|interpro:IPR032319|mint:Q5SY16|reactome:R-HSA-6791226|ensembl:ENSG00000162408(gene)|refseq:XP_016857827.1|refseq:XP_016857828.1 go:"GO:0005634"(nucleus) - - figure legend:ST3 F2C|comment:proteins that were enriched in the induced sample more than 6-fold|dataset:Brain Disease - Neurological Diseases & Disorders|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-daoy)|taxid:9606(Homo sapiens DAOY cerebellar medulloblastoma cell line) - 2020/12/29 2020/12/29 rogid:cn8gYfKDpQc8J2ygnqny32sIyyU9606 rogid:IWGhuh/G+MlTxlSXEcIml8tvK7Y9606 rigid:Cnhili6Os5i+9KsmWx3iqclZGC0 false tandem tag:n-n - - - psi-mi:"MI:0658"(multidimensional protein identification technology) psi-mi:"MI:0658"(multidimensional protein identification technology) uniprotkb:P48431 uniprotkb:Q8NDX5 intact:EBI-6124081|uniprotkb:Q14537|ensembl:ENSP00000323588 intact:EBI-1223801|uniprotkb:Q5HYF0|uniprotkb:Q6NSG2|uniprotkb:Q8NFT7|uniprotkb:Q8NFZ1|uniprotkb:Q8TBM2|uniprotkb:Q9H971|uniprotkb:Q9H9I4|uniprotkb:A2RRP9|ensembl:ENSP00000420271 psi-mi:sox2_human(display_long)|uniprotkb:SOX2(gene name)|psi-mi:SOX2(display_short) psi-mi:phc3_human(display_long)|uniprotkb:PHC3(gene name)|psi-mi:PHC3(display_short)|uniprotkb:EDR3(gene name synonym)|uniprotkb:PH3(gene name synonym)|uniprotkb:Homolog of polyhomeotic 3(gene name synonym)|uniprotkb:Early development regulatory protein 3(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Cox et al. (2012) pubmed:23667531|imex:IM-28599 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-26574478|imex:IM-28599-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_003097.1|dip:DIP-59913N|ensembl:ENSG00000181449(gene)|ensembl:ENST00000325404(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001649"(osteoblast differentiation)|go:"GO:0001654"(eye development)|go:"GO:0001714"(endodermal cell fate specification)|go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006325"(chromatin organization)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0009611"(response to wounding)|go:"GO:0009653"(anatomical structure morphogenesis)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0021781"(glial cell fate commitment)|go:"GO:0021983"(pituitary gland development)|go:"GO:0021984"(adenohypophysis development)|go:"GO:0022409"(positive regulation of cell-cell adhesion)|go:"GO:0030154"(cell differentiation)|go:"GO:0030900"(forebrain development)|go:"GO:0035019"(somatic stem cell population maintenance)|go:"GO:0035198"(miRNA binding)|go:"GO:0042246"(tissue regeneration)|go:"GO:0043281"(regulation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0043410"(positive regulation of MAPK cascade)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045165"(cell fate commitment)|go:"GO:0045597"(positive regulation of cell differentiation)|go:"GO:0045665"(negative regulation of neuron differentiation)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048839"(inner ear development)|go:"GO:0050680"(negative regulation of epithelial cell proliferation)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0070848"(response to growth factor)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:0097150"(neuronal stem cell population maintenance)|interpro:IPR009071(High mobility group box, HMG)|interpro:IPR022097|interpro:IPR032643|interpro:IPR036910|mint:P48431|rcsb pdb:1O4X|rcsb pdb:2LE4|rcsb pdb:6T7B|rcsb pdb:6T90|rcsb pdb:6WX7|rcsb pdb:6WX8|rcsb pdb:6WX9|rcsb pdb:6YOV|reactome:R-HSA-2892245|reactome:R-HSA-2892247|reactome:R-HSA-3769402|reactome:R-HSA-452723|reactome:R-HSA-6785807|reactome:R-HSA-8986944 refseq:NP_079223.3|refseq:NP_001295045.1|ensembl:ENSP00000420271|ensembl:ENST00000495893|ensembl:ENSP00000420294|ensembl:ENST00000497658|ensembl:ENSP00000420454|ensembl:ENSG00000173889(gene)|ensembl:ENST00000494943(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0008270"(zinc ion binding)|go:"GO:0031519"(PcG protein complex)|go:"GO:0035102"(PRC1 complex)|go:"GO:0042393"(histone binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|interpro:IPR001660(Sterile alpha motif SAM)|interpro:IPR012313(Zinc finger, FCS-type)|interpro:IPR013761(Sterile alpha motif-type)|interpro:IPR038603|mint:Q8NDX5|rcsb pdb:4PZN|rcsb pdb:4PZO|reactome:R-HSA-2559580|reactome:R-HSA-3108214|reactome:R-HSA-3899300|reactome:R-HSA-4551638|reactome:R-HSA-4570464|reactome:R-HSA-4655427|reactome:R-HSA-8939243|reactome:R-HSA-8943724|reactome:R-HSA-8953750 go:"GO:0005634"(nucleus) - - figure legend:ST3 F2C|comment:proteins that were enriched in the induced sample more than 6-fold|dataset:Brain Disease - Neurological Diseases & Disorders|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-daoy)|taxid:9606(Homo sapiens DAOY cerebellar medulloblastoma cell line) - 2020/12/29 2020/12/29 rogid:cn8gYfKDpQc8J2ygnqny32sIyyU9606 rogid:hB1EMs+lCv19uuJ1O7+QiVCUoo89606 rigid:Cnhili6Os5i+9KsmWx3iqclZGC0 false tandem tag:n-n - - - psi-mi:"MI:0658"(multidimensional protein identification technology) psi-mi:"MI:0658"(multidimensional protein identification technology) uniprotkb:P48431 uniprotkb:Q2KHR3 intact:EBI-6124081|uniprotkb:Q14537|ensembl:ENSP00000323588 intact:EBI-11048246|uniprotkb:Q6ZUR5|uniprotkb:Q6ZU30|ensembl:ENSP00000382241 psi-mi:sox2_human(display_long)|uniprotkb:SOX2(gene name)|psi-mi:SOX2(display_short) psi-mi:qser1_human(display_long)|uniprotkb:QSER1(gene name)|psi-mi:QSER1(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Cox et al. (2012) pubmed:23667531|imex:IM-28599 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-26574478|imex:IM-28599-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_003097.1|dip:DIP-59913N|ensembl:ENSG00000181449(gene)|ensembl:ENST00000325404(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001649"(osteoblast differentiation)|go:"GO:0001654"(eye development)|go:"GO:0001714"(endodermal cell fate specification)|go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006325"(chromatin organization)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0009611"(response to wounding)|go:"GO:0009653"(anatomical structure morphogenesis)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0021781"(glial cell fate commitment)|go:"GO:0021983"(pituitary gland development)|go:"GO:0021984"(adenohypophysis development)|go:"GO:0022409"(positive regulation of cell-cell adhesion)|go:"GO:0030154"(cell differentiation)|go:"GO:0030900"(forebrain development)|go:"GO:0035019"(somatic stem cell population maintenance)|go:"GO:0035198"(miRNA binding)|go:"GO:0042246"(tissue regeneration)|go:"GO:0043281"(regulation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0043410"(positive regulation of MAPK cascade)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045165"(cell fate commitment)|go:"GO:0045597"(positive regulation of cell differentiation)|go:"GO:0045665"(negative regulation of neuron differentiation)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048839"(inner ear development)|go:"GO:0050680"(negative regulation of epithelial cell proliferation)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0070848"(response to growth factor)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:0097150"(neuronal stem cell population maintenance)|interpro:IPR009071(High mobility group box, HMG)|interpro:IPR022097|interpro:IPR032643|interpro:IPR036910|mint:P48431|rcsb pdb:1O4X|rcsb pdb:2LE4|rcsb pdb:6T7B|rcsb pdb:6T90|rcsb pdb:6WX7|rcsb pdb:6WX8|rcsb pdb:6WX9|rcsb pdb:6YOV|reactome:R-HSA-2892245|reactome:R-HSA-2892247|reactome:R-HSA-3769402|reactome:R-HSA-452723|reactome:R-HSA-6785807|reactome:R-HSA-8986944 refseq:NP_001070254.1|ensembl:ENSG00000060749(gene)|ensembl:ENST00000399302(transcript)|interpro:IPR025451|mint:Q2KHR3 go:"GO:0005634"(nucleus) - - figure legend:ST3 F2C|comment:proteins that were enriched in the induced sample more than 6-fold|dataset:Brain Disease - Neurological Diseases & Disorders|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-daoy)|taxid:9606(Homo sapiens DAOY cerebellar medulloblastoma cell line) - 2020/12/29 2020/12/29 rogid:cn8gYfKDpQc8J2ygnqny32sIyyU9606 rogid:vDgZ99Lo5fIvl2ef739OtWP/QLQ9606 rigid:Cnhili6Os5i+9KsmWx3iqclZGC0 false tandem tag:n-n - - - psi-mi:"MI:0658"(multidimensional protein identification technology) psi-mi:"MI:0658"(multidimensional protein identification technology) uniprotkb:P48431 uniprotkb:P48431 intact:EBI-6124081|uniprotkb:Q14537|ensembl:ENSP00000323588 intact:EBI-6124081|uniprotkb:Q14537|ensembl:ENSP00000323588 psi-mi:sox2_human(display_long)|uniprotkb:SOX2(gene name)|psi-mi:SOX2(display_short) psi-mi:sox2_human(display_long)|uniprotkb:SOX2(gene name)|psi-mi:SOX2(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Cox et al. (2012) pubmed:23667531|imex:IM-28599 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-26574478|imex:IM-28599-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_003097.1|dip:DIP-59913N|ensembl:ENSG00000181449(gene)|ensembl:ENST00000325404(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001649"(osteoblast differentiation)|go:"GO:0001654"(eye development)|go:"GO:0001714"(endodermal cell fate specification)|go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006325"(chromatin organization)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0009611"(response to wounding)|go:"GO:0009653"(anatomical structure morphogenesis)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0021781"(glial cell fate commitment)|go:"GO:0021983"(pituitary gland development)|go:"GO:0021984"(adenohypophysis development)|go:"GO:0022409"(positive regulation of cell-cell adhesion)|go:"GO:0030154"(cell differentiation)|go:"GO:0030900"(forebrain development)|go:"GO:0035019"(somatic stem cell population maintenance)|go:"GO:0035198"(miRNA binding)|go:"GO:0042246"(tissue regeneration)|go:"GO:0043281"(regulation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0043410"(positive regulation of MAPK cascade)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045165"(cell fate commitment)|go:"GO:0045597"(positive regulation of cell differentiation)|go:"GO:0045665"(negative regulation of neuron differentiation)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048839"(inner ear development)|go:"GO:0050680"(negative regulation of epithelial cell proliferation)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0070848"(response to growth factor)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:0097150"(neuronal stem cell population maintenance)|interpro:IPR009071(High mobility group box, HMG)|interpro:IPR022097|interpro:IPR032643|interpro:IPR036910|mint:P48431|rcsb pdb:1O4X|rcsb pdb:2LE4|rcsb pdb:6T7B|rcsb pdb:6T90|rcsb pdb:6WX7|rcsb pdb:6WX8|rcsb pdb:6WX9|rcsb pdb:6YOV|reactome:R-HSA-2892245|reactome:R-HSA-2892247|reactome:R-HSA-3769402|reactome:R-HSA-452723|reactome:R-HSA-6785807|reactome:R-HSA-8986944 refseq:NP_003097.1|dip:DIP-59913N|ensembl:ENSG00000181449(gene)|ensembl:ENST00000325404(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001649"(osteoblast differentiation)|go:"GO:0001654"(eye development)|go:"GO:0001714"(endodermal cell fate specification)|go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006325"(chromatin organization)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0009611"(response to wounding)|go:"GO:0009653"(anatomical structure morphogenesis)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0021781"(glial cell fate commitment)|go:"GO:0021983"(pituitary gland development)|go:"GO:0021984"(adenohypophysis development)|go:"GO:0022409"(positive regulation of cell-cell adhesion)|go:"GO:0030154"(cell differentiation)|go:"GO:0030900"(forebrain development)|go:"GO:0035019"(somatic stem cell population maintenance)|go:"GO:0035198"(miRNA binding)|go:"GO:0042246"(tissue regeneration)|go:"GO:0043281"(regulation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0043410"(positive regulation of MAPK cascade)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045165"(cell fate commitment)|go:"GO:0045597"(positive regulation of cell differentiation)|go:"GO:0045665"(negative regulation of neuron differentiation)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048839"(inner ear development)|go:"GO:0050680"(negative regulation of epithelial cell proliferation)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0070848"(response to growth factor)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:0097150"(neuronal stem cell population maintenance)|interpro:IPR009071(High mobility group box, HMG)|interpro:IPR022097|interpro:IPR032643|interpro:IPR036910|mint:P48431|rcsb pdb:1O4X|rcsb pdb:2LE4|rcsb pdb:6T7B|rcsb pdb:6T90|rcsb pdb:6WX7|rcsb pdb:6WX8|rcsb pdb:6WX9|rcsb pdb:6YOV|reactome:R-HSA-2892245|reactome:R-HSA-2892247|reactome:R-HSA-3769402|reactome:R-HSA-452723|reactome:R-HSA-6785807|reactome:R-HSA-8986944 go:"GO:0005634"(nucleus) - - figure legend:ST3 F2C|comment:proteins that were enriched in the induced sample more than 6-fold|dataset:Brain Disease - Neurological Diseases & Disorders|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-daoy)|taxid:9606(Homo sapiens DAOY cerebellar medulloblastoma cell line) - 2020/12/29 2020/12/29 rogid:cn8gYfKDpQc8J2ygnqny32sIyyU9606 rogid:cn8gYfKDpQc8J2ygnqny32sIyyU9606 rigid:Cnhili6Os5i+9KsmWx3iqclZGC0 false tandem tag:n-n - - - psi-mi:"MI:0658"(multidimensional protein identification technology) psi-mi:"MI:0658"(multidimensional protein identification technology) uniprotkb:P48431 uniprotkb:Q7Z7L1 intact:EBI-6124081|uniprotkb:Q14537|ensembl:ENSP00000323588 intact:EBI-1052253|uniprotkb:Q8N3S8|uniprotkb:Q8N762|uniprotkb:Q8TEE0|uniprotkb:E1P643|ensembl:ENSP00000312402|ensembl:ENSP00000378067 psi-mi:sox2_human(display_long)|uniprotkb:SOX2(gene name)|psi-mi:SOX2(display_short) psi-mi:sln11_human(display_long)|uniprotkb:SLFN11(gene name)|psi-mi:SLFN11(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Cox et al. (2012) pubmed:23667531|imex:IM-28599 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-26574478|imex:IM-28599-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_003097.1|dip:DIP-59913N|ensembl:ENSG00000181449(gene)|ensembl:ENST00000325404(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001649"(osteoblast differentiation)|go:"GO:0001654"(eye development)|go:"GO:0001714"(endodermal cell fate specification)|go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006325"(chromatin organization)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0009611"(response to wounding)|go:"GO:0009653"(anatomical structure morphogenesis)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0021781"(glial cell fate commitment)|go:"GO:0021983"(pituitary gland development)|go:"GO:0021984"(adenohypophysis development)|go:"GO:0022409"(positive regulation of cell-cell adhesion)|go:"GO:0030154"(cell differentiation)|go:"GO:0030900"(forebrain development)|go:"GO:0035019"(somatic stem cell population maintenance)|go:"GO:0035198"(miRNA binding)|go:"GO:0042246"(tissue regeneration)|go:"GO:0043281"(regulation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0043410"(positive regulation of MAPK cascade)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045165"(cell fate commitment)|go:"GO:0045597"(positive regulation of cell differentiation)|go:"GO:0045665"(negative regulation of neuron differentiation)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048839"(inner ear development)|go:"GO:0050680"(negative regulation of epithelial cell proliferation)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0070848"(response to growth factor)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:0097150"(neuronal stem cell population maintenance)|interpro:IPR009071(High mobility group box, HMG)|interpro:IPR022097|interpro:IPR032643|interpro:IPR036910|mint:P48431|rcsb pdb:1O4X|rcsb pdb:2LE4|rcsb pdb:6T7B|rcsb pdb:6T90|rcsb pdb:6WX7|rcsb pdb:6WX8|rcsb pdb:6WX9|rcsb pdb:6YOV|reactome:R-HSA-2892245|reactome:R-HSA-2892247|reactome:R-HSA-3769402|reactome:R-HSA-452723|reactome:R-HSA-6785807|reactome:R-HSA-8986944 refseq:NP_001098057.1|refseq:NP_001098058.1|refseq:NP_001098059.1|refseq:NP_001098060.1|refseq:NP_689483.3|refseq:XP_011523767.1|refseq:XP_005258125.1|go:"GO:0005829"(cytosol)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0008156"(negative regulation of DNA replication)|go:"GO:0010942"(positive regulation of cell death)|ensembl:ENSG00000172716(gene)|go:"GO:0043111"(replication fork arrest)|ensembl:ENST00000308377(transcript)|ensembl:ENST00000394566(transcript)|go:"GO:0000049"(tRNA binding)|go:"GO:0051607"(defense response to virus)|go:"GO:0004386"(helicase activity)|go:"GO:0090734"(site of DNA damage)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|go:"GO:0005524"(ATP binding)|go:"GO:2000134"(negative regulation of G1/S transition of mitotic cell cycle)|interpro:IPR007421(ATPase associated with various cellular activities, AAA-4)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|interpro:IPR018647|interpro:IPR027417|interpro:IPR029684|interpro:IPR038461|mint:Q7Z7L1|refseq:XP_006722234.1|refseq:XP_016880788.1 go:"GO:0005634"(nucleus) - - figure legend:ST3 F2C|comment:proteins that were enriched in the induced sample more than 6-fold|dataset:Brain Disease - Neurological Diseases & Disorders|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-daoy)|taxid:9606(Homo sapiens DAOY cerebellar medulloblastoma cell line) - 2020/12/29 2020/12/29 rogid:cn8gYfKDpQc8J2ygnqny32sIyyU9606 rogid:52pyX1VK+Z/vzzmgci5rF+EbQTA9606 rigid:Cnhili6Os5i+9KsmWx3iqclZGC0 false tandem tag:n-n - - - psi-mi:"MI:0658"(multidimensional protein identification technology) psi-mi:"MI:0658"(multidimensional protein identification technology) uniprotkb:P48431 uniprotkb:Q92688 intact:EBI-6124081|uniprotkb:Q14537|ensembl:ENSP00000323588 intact:EBI-762428|uniprotkb:O00655|uniprotkb:P78458|uniprotkb:P78459|uniprotkb:B2R9C7|ensembl:ENSP00000345848 psi-mi:sox2_human(display_long)|uniprotkb:SOX2(gene name)|psi-mi:SOX2(display_short) psi-mi:an32b_human(display_long)|uniprotkb:Acidic protein rich in leucines(gene name synonym)|uniprotkb:Silver-stainable protein SSP29(gene name synonym)|uniprotkb:ANP32B(gene name)|psi-mi:ANP32B(display_short)|uniprotkb:APRIL(gene name synonym)|uniprotkb:PHAPI2(gene name synonym)|uniprotkb:Putative HLA-DR-associated protein I-2(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Cox et al. (2012) pubmed:23667531|imex:IM-28599 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-26574478|imex:IM-28599-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_003097.1|dip:DIP-59913N|ensembl:ENSG00000181449(gene)|ensembl:ENST00000325404(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001649"(osteoblast differentiation)|go:"GO:0001654"(eye development)|go:"GO:0001714"(endodermal cell fate specification)|go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006325"(chromatin organization)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0009611"(response to wounding)|go:"GO:0009653"(anatomical structure morphogenesis)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0021781"(glial cell fate commitment)|go:"GO:0021983"(pituitary gland development)|go:"GO:0021984"(adenohypophysis development)|go:"GO:0022409"(positive regulation of cell-cell adhesion)|go:"GO:0030154"(cell differentiation)|go:"GO:0030900"(forebrain development)|go:"GO:0035019"(somatic stem cell population maintenance)|go:"GO:0035198"(miRNA binding)|go:"GO:0042246"(tissue regeneration)|go:"GO:0043281"(regulation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0043410"(positive regulation of MAPK cascade)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045165"(cell fate commitment)|go:"GO:0045597"(positive regulation of cell differentiation)|go:"GO:0045665"(negative regulation of neuron differentiation)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048839"(inner ear development)|go:"GO:0050680"(negative regulation of epithelial cell proliferation)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0070848"(response to growth factor)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:0097150"(neuronal stem cell population maintenance)|interpro:IPR009071(High mobility group box, HMG)|interpro:IPR022097|interpro:IPR032643|interpro:IPR036910|mint:P48431|rcsb pdb:1O4X|rcsb pdb:2LE4|rcsb pdb:6T7B|rcsb pdb:6T90|rcsb pdb:6WX7|rcsb pdb:6WX8|rcsb pdb:6WX9|rcsb pdb:6YOV|reactome:R-HSA-2892245|reactome:R-HSA-2892247|reactome:R-HSA-3769402|reactome:R-HSA-452723|reactome:R-HSA-6785807|reactome:R-HSA-8986944 refseq:NP_006392.1|ensembl:ENSG00000136938(gene)|ensembl:ENST00000339399(transcript)|go:"GO:0001944"(vasculature development)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006334"(nucleosome assembly)|go:"GO:0006919"(activation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0021591"(ventricular system development)|go:"GO:0042393"(histone binding)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0045596"(negative regulation of cell differentiation)|go:"GO:0046827"(positive regulation of protein export from nucleus)|go:"GO:0048839"(inner ear development)|go:"GO:0060021"(roof of mouth development)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070063"(RNA polymerase binding)|interpro:IPR001611(Leucine-rich repeat)|interpro:IPR032675|mint:Q92688|rcsb pdb:2ELL|rcsb pdb:2RR6|interpro:IPR003603(U2A'/phosphoprotein 32 family A, C-terminal) go:"GO:0005634"(nucleus) - - figure legend:ST3 F2C|comment:proteins that were enriched in the induced sample more than 6-fold|dataset:Brain Disease - Neurological Diseases & Disorders|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-daoy)|taxid:9606(Homo sapiens DAOY cerebellar medulloblastoma cell line) - 2020/12/29 2020/12/29 rogid:cn8gYfKDpQc8J2ygnqny32sIyyU9606 rogid:8eu0C8oHWUrZ28F2fIup9o5MDYk9606 rigid:Cnhili6Os5i+9KsmWx3iqclZGC0 false tandem tag:n-n - - - psi-mi:"MI:0658"(multidimensional protein identification technology) psi-mi:"MI:0658"(multidimensional protein identification technology) uniprotkb:P48431 uniprotkb:Q13885 intact:EBI-6124081|uniprotkb:Q14537|ensembl:ENSP00000323588 intact:EBI-711595|ensembl:ENSP00000369703|uniprotkb:Q6FGZ8|uniprotkb:Q8IWR2 psi-mi:sox2_human(display_long)|uniprotkb:SOX2(gene name)|psi-mi:SOX2(display_short) psi-mi:tbb2a_human(display_long)|uniprotkb:TUBB2A(gene name)|psi-mi:TUBB2A(display_short)|uniprotkb:TUBB2(gene name synonym)|uniprotkb:Tubulin beta class IIa(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Cox et al. (2012) pubmed:23667531|imex:IM-28599 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-26574478|imex:IM-28599-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_003097.1|dip:DIP-59913N|ensembl:ENSG00000181449(gene)|ensembl:ENST00000325404(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001649"(osteoblast differentiation)|go:"GO:0001654"(eye development)|go:"GO:0001714"(endodermal cell fate specification)|go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006325"(chromatin organization)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0009611"(response to wounding)|go:"GO:0009653"(anatomical structure morphogenesis)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0021781"(glial cell fate commitment)|go:"GO:0021983"(pituitary gland development)|go:"GO:0021984"(adenohypophysis development)|go:"GO:0022409"(positive regulation of cell-cell adhesion)|go:"GO:0030154"(cell differentiation)|go:"GO:0030900"(forebrain development)|go:"GO:0035019"(somatic stem cell population maintenance)|go:"GO:0035198"(miRNA binding)|go:"GO:0042246"(tissue regeneration)|go:"GO:0043281"(regulation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0043410"(positive regulation of MAPK cascade)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045165"(cell fate commitment)|go:"GO:0045597"(positive regulation of cell differentiation)|go:"GO:0045665"(negative regulation of neuron differentiation)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048839"(inner ear development)|go:"GO:0050680"(negative regulation of epithelial cell proliferation)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0070848"(response to growth factor)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:0097150"(neuronal stem cell population maintenance)|interpro:IPR009071(High mobility group box, HMG)|interpro:IPR022097|interpro:IPR032643|interpro:IPR036910|mint:P48431|rcsb pdb:1O4X|rcsb pdb:2LE4|rcsb pdb:6T7B|rcsb pdb:6T90|rcsb pdb:6WX7|rcsb pdb:6WX8|rcsb pdb:6WX9|rcsb pdb:6YOV|reactome:R-HSA-2892245|reactome:R-HSA-2892247|reactome:R-HSA-3769402|reactome:R-HSA-452723|reactome:R-HSA-6785807|reactome:R-HSA-8986944 reactome:R-HSA-389960|reactome:R-HSA-389977|reactome:R-HSA-437239|reactome:R-HSA-5610787|reactome:R-HSA-5617833|reactome:R-HSA-5620924|reactome:R-HSA-5626467|reactome:R-HSA-5663220|reactome:R-HSA-6807878|reactome:R-HSA-6811434|reactome:R-HSA-6811436|reactome:R-HSA-68877|reactome:R-HSA-8852276|reactome:R-HSA-8955332|reactome:R-HSA-9609690|reactome:R-HSA-9609736|reactome:R-HSA-9619483|reactome:R-HSA-9646399|reactome:R-HSA-9648025|reactome:R-HSA-389957|reactome:R-HSA-983189|reactome:R-HSA-9668328|ensembl:ENSG00000137267(gene)|ensembl:ENST00000333628(transcript)|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0001764"(neuron migration)|go:"GO:0005200"(structural constituent of cytoskeleton)|go:"GO:0005525"(GTP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005874"(microtubule)|go:"GO:0070062"(extracellular exosome)|go:"GO:1903561"(extracellular vesicle)|interpro:IPR000217(Tubulin)|interpro:IPR002453(Beta tubulin)|interpro:IPR003008(Tubulin/FtsZ, GTPase)|interpro:IPR008280(Tubulin/FtsZ, C-terminal)|interpro:IPR013838(Beta tubulin, autoregulation binding site)|interpro:IPR017975|interpro:IPR018316|interpro:IPR023123|interpro:IPR036525|interpro:IPR037103|mint:Q13885|reactome:R-HSA-1445148|reactome:R-HSA-190840|reactome:R-HSA-190861|reactome:R-HSA-2132295|reactome:R-HSA-2467813|reactome:R-HSA-2500257|reactome:R-HSA-3371497|reactome:R-HSA-380320|refseq:NP_001060.1|refseq:NP_001297244.1 go:"GO:0005634"(nucleus) - - figure legend:ST3 F2C|comment:proteins that were enriched in the induced sample more than 6-fold|dataset:Brain Disease - Neurological Diseases & Disorders|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-daoy)|taxid:9606(Homo sapiens DAOY cerebellar medulloblastoma cell line) - 2020/12/29 2020/12/29 rogid:cn8gYfKDpQc8J2ygnqny32sIyyU9606 rogid:XN9uTGU0KxQjMod0AGnM+XJoHyk9606 rigid:Cnhili6Os5i+9KsmWx3iqclZGC0 false tandem tag:n-n - - - psi-mi:"MI:0658"(multidimensional protein identification technology) psi-mi:"MI:0658"(multidimensional protein identification technology) uniprotkb:P48431 uniprotkb:Q86VI3 intact:EBI-6124081|uniprotkb:Q14537|ensembl:ENSP00000323588 intact:EBI-1237354|uniprotkb:Q5T3H8|ensembl:ENSP00000354451 psi-mi:sox2_human(display_long)|uniprotkb:SOX2(gene name)|psi-mi:SOX2(display_short) psi-mi:iqga3_human(display_long)|uniprotkb:IQGAP3(gene name)|psi-mi:IQGAP3(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Cox et al. (2012) pubmed:23667531|imex:IM-28599 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-26574478|imex:IM-28599-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_003097.1|dip:DIP-59913N|ensembl:ENSG00000181449(gene)|ensembl:ENST00000325404(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001649"(osteoblast differentiation)|go:"GO:0001654"(eye development)|go:"GO:0001714"(endodermal cell fate specification)|go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006325"(chromatin organization)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0009611"(response to wounding)|go:"GO:0009653"(anatomical structure morphogenesis)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0021781"(glial cell fate commitment)|go:"GO:0021983"(pituitary gland development)|go:"GO:0021984"(adenohypophysis development)|go:"GO:0022409"(positive regulation of cell-cell adhesion)|go:"GO:0030154"(cell differentiation)|go:"GO:0030900"(forebrain development)|go:"GO:0035019"(somatic stem cell population maintenance)|go:"GO:0035198"(miRNA binding)|go:"GO:0042246"(tissue regeneration)|go:"GO:0043281"(regulation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0043410"(positive regulation of MAPK cascade)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045165"(cell fate commitment)|go:"GO:0045597"(positive regulation of cell differentiation)|go:"GO:0045665"(negative regulation of neuron differentiation)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048839"(inner ear development)|go:"GO:0050680"(negative regulation of epithelial cell proliferation)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0070848"(response to growth factor)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:0097150"(neuronal stem cell population maintenance)|interpro:IPR009071(High mobility group box, HMG)|interpro:IPR022097|interpro:IPR032643|interpro:IPR036910|mint:P48431|rcsb pdb:1O4X|rcsb pdb:2LE4|rcsb pdb:6T7B|rcsb pdb:6T90|rcsb pdb:6WX7|rcsb pdb:6WX8|rcsb pdb:6WX9|rcsb pdb:6YOV|reactome:R-HSA-2892245|reactome:R-HSA-2892247|reactome:R-HSA-3769402|reactome:R-HSA-452723|reactome:R-HSA-6785807|reactome:R-HSA-8986944 refseq:NP_839943.2|ensembl:ENSP00000354451|ensembl:ENSG00000183856(gene)|ensembl:ENST00000361170(transcript)|go:"GO:0000082"(G1/S transition of mitotic cell cycle)|go:"GO:0001934"(positive regulation of protein phosphorylation)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005911"(cell-cell junction)|go:"GO:0007265"(Ras protein signal transduction)|go:"GO:0008361"(regulation of cell size)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0016328"(lateral plasma membrane)|go:"GO:0031267"(small GTPase binding)|go:"GO:0032956"(regulation of actin cytoskeleton organization)|go:"GO:0033601"(positive regulation of mammary gland epithelial cell proliferation)|go:"GO:0043087"(regulation of GTPase activity)|go:"GO:0043410"(positive regulation of MAPK cascade)|go:"GO:0051015"(actin filament binding)|go:"GO:0070371"(ERK1 and ERK2 cascade)|go:"GO:0070856"(myosin VI light chain binding)|go:"GO:0071310"(cellular response to organic substance)|interpro:IPR000048(IQ calmodulin-binding region)|interpro:IPR000593(RasGAP protein, C-terminal)|interpro:IPR001715(Calponin-like actin-binding)|interpro:IPR001936(Ras GTPase-activating protein)|interpro:IPR008936(Rho GTPase activation protein)|interpro:IPR023152|mint:Q86VI3|rcsb pdb:3ISU|reactome:R-HSA-5626467|reactome:R-HSA-8980692|reactome:R-HSA-9013026|reactome:R-HSA-9013106|reactome:R-HSA-9013148|reactome:R-HSA-9013149|reactome:R-HSA-9013406|reactome:R-HSA-9013409|interpro:IPR036872 go:"GO:0005634"(nucleus) - - figure legend:ST3 F2C|comment:proteins that were enriched in the induced sample more than 6-fold|dataset:Brain Disease - Neurological Diseases & Disorders|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-daoy)|taxid:9606(Homo sapiens DAOY cerebellar medulloblastoma cell line) - 2020/12/29 2020/12/29 rogid:cn8gYfKDpQc8J2ygnqny32sIyyU9606 rogid:5lIYEC2lJihenWFio0Q+1W9EINI9606 rigid:Cnhili6Os5i+9KsmWx3iqclZGC0 false tandem tag:n-n - - - psi-mi:"MI:0658"(multidimensional protein identification technology) psi-mi:"MI:0658"(multidimensional protein identification technology) uniprotkb:P48431 uniprotkb:P27797 intact:EBI-6124081|uniprotkb:Q14537|ensembl:ENSP00000323588 intact:EBI-1049597|uniprotkb:Q6IAT4|uniprotkb:Q9UDG2|ensembl:ENSP00000320866|ensembl:ENSP00000466037 psi-mi:sox2_human(display_long)|uniprotkb:SOX2(gene name)|psi-mi:SOX2(display_short) psi-mi:calr_human(display_long)|uniprotkb:CRP55(gene name synonym)|uniprotkb:Calregulin(gene name synonym)|uniprotkb:HACBP(gene name synonym)|uniprotkb:Endoplasmic reticulum resident protein 60(gene name synonym)|uniprotkb:grp60(gene name synonym)|uniprotkb:CALR(gene name)|psi-mi:CALR(display_short)|uniprotkb:CRTC(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Cox et al. (2012) pubmed:23667531|imex:IM-28599 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-26574478|imex:IM-28599-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_003097.1|dip:DIP-59913N|ensembl:ENSG00000181449(gene)|ensembl:ENST00000325404(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001649"(osteoblast differentiation)|go:"GO:0001654"(eye development)|go:"GO:0001714"(endodermal cell fate specification)|go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006325"(chromatin organization)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0009611"(response to wounding)|go:"GO:0009653"(anatomical structure morphogenesis)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0021781"(glial cell fate commitment)|go:"GO:0021983"(pituitary gland development)|go:"GO:0021984"(adenohypophysis development)|go:"GO:0022409"(positive regulation of cell-cell adhesion)|go:"GO:0030154"(cell differentiation)|go:"GO:0030900"(forebrain development)|go:"GO:0035019"(somatic stem cell population maintenance)|go:"GO:0035198"(miRNA binding)|go:"GO:0042246"(tissue regeneration)|go:"GO:0043281"(regulation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0043410"(positive regulation of MAPK cascade)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045165"(cell fate commitment)|go:"GO:0045597"(positive regulation of cell differentiation)|go:"GO:0045665"(negative regulation of neuron differentiation)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048839"(inner ear development)|go:"GO:0050680"(negative regulation of epithelial cell proliferation)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0070848"(response to growth factor)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:0097150"(neuronal stem cell population maintenance)|interpro:IPR009071(High mobility group box, HMG)|interpro:IPR022097|interpro:IPR032643|interpro:IPR036910|mint:P48431|rcsb pdb:1O4X|rcsb pdb:2LE4|rcsb pdb:6T7B|rcsb pdb:6T90|rcsb pdb:6WX7|rcsb pdb:6WX8|rcsb pdb:6WX9|rcsb pdb:6YOV|reactome:R-HSA-2892245|reactome:R-HSA-2892247|reactome:R-HSA-3769402|reactome:R-HSA-452723|reactome:R-HSA-6785807|reactome:R-HSA-8986944 refseq:NP_004334.1|ensembl:ENSG00000179218(gene)|ensembl:ENST00000316448(transcript)|ensembl:ENST00000586967(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0001669"(acrosomal vesicle)|go:"GO:0001849"(complement component C1q complex binding)|go:"GO:0002502"(peptide antigen assembly with MHC class I protein complex)|go:"GO:0003677"(DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0005178"(integrin binding)|go:"GO:0005506"(iron ion binding)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0005634"(nucleus)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005737"(cytoplasm)|go:"GO:0005764"(lysosome)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005788"(endoplasmic reticulum lumen)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005790"(smooth endoplasmic reticulum)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0005844"(polysome)|go:"GO:0005925"(focal adhesion)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006457"(protein folding)|go:"GO:0006611"(protein export from nucleus)|go:"GO:0007283"(spermatogenesis)|go:"GO:0008270"(zinc ion binding)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0009897"(external side of plasma membrane)|go:"GO:0009986"(cell surface)|go:"GO:0010595"(positive regulation of endothelial cell migration)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0016020"(membrane)|go:"GO:0017148"(negative regulation of translation)|go:"GO:0022417"(protein maturation by protein folding)|go:"GO:0030246"(carbohydrate binding)|go:"GO:0030670"(phagocytic vesicle membrane)|go:"GO:0030866"(cortical actin cytoskeleton organization)|go:"GO:0030968"(endoplasmic reticulum unfolded protein response)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032355"(response to estradiol)|go:"GO:0033018"(sarcoplasmic reticulum lumen)|go:"GO:0033116"(endoplasmic reticulum-Golgi intermediate compartment membrane)|go:"GO:0033144"(negative regulation of intracellular steroid hormone receptor signaling pathway)|go:"GO:0033574"(response to testosterone)|go:"GO:0034504"(protein localization to nucleus)|go:"GO:0034975"(protein folding in endoplasmic reticulum)|go:"GO:0040020"(regulation of meiotic nuclear division)|go:"GO:0042277"(peptide binding)|go:"GO:0042493"|go:"GO:0042562"(hormone binding)|go:"GO:0042824"(MHC class I peptide loading complex)|go:"GO:0042921"(glucocorticoid receptor signaling pathway)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0044183"(protein folding chaperone)|go:"GO:0044322"(endoplasmic reticulum quality control compartment)|go:"GO:0045665"(negative regulation of neuron differentiation)|go:"GO:0045787"(positive regulation of cell cycle)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0048387"(negative regulation of retinoic acid receptor signaling pathway)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0050681"(androgen receptor binding)|go:"GO:0050766"(positive regulation of phagocytosis)|go:"GO:0050821"(protein stabilization)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0051087"(chaperone binding)|go:"GO:0051208"(sequestering of calcium ion)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0006874"(cellular calcium ion homeostasis)|go:"GO:0055007"(cardiac muscle cell differentiation)|go:"GO:0060473"(cortical granule)|go:"GO:0062023"(collagen-containing extracellular matrix)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071285"(cellular response to lithium ion)|go:"GO:0071556"(integral component of lumenal side of endoplasmic reticulum membrane)|go:"GO:0071682"(endocytic vesicle lumen)|go:"GO:0090398"(cellular senescence)|go:"GO:1900026"(positive regulation of substrate adhesion-dependent cell spreading)|go:"GO:1901164"(negative regulation of trophoblast cell migration)|go:"GO:1901224"(positive regulation of NIK/NF-kappaB signaling)|go:"GO:2000510"(positive regulation of dendritic cell chemotaxis)|interpro:IPR001580(Calreticulin/calnexin)|interpro:IPR009033(Calreticulin/calnexin, P)|interpro:IPR009169(Calreticulin)|interpro:IPR013320(Concanavalin A-like lectin/glucanase, subgroup)|interpro:IPR018124|mint:P27797|rcsb pdb:2CLR|rcsb pdb:3DOW|rcsb pdb:3POS|rcsb pdb:3POW|rcsb pdb:5LK5|rcsb pdb:5V90|rcsb pdb:6ENY|reactome:R-HSA-1236974|reactome:R-HSA-168316|reactome:R-HSA-3000480|reactome:R-HSA-3000484|reactome:R-HSA-381183|reactome:R-HSA-901042|reactome:R-HSA-983170|dip:DIP-104N go:"GO:0005634"(nucleus) - - figure legend:ST3 F2C|comment:proteins that were enriched in the induced sample more than 6-fold|dataset:Brain Disease - Neurological Diseases & Disorders|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-daoy)|taxid:9606(Homo sapiens DAOY cerebellar medulloblastoma cell line) - 2020/12/29 2020/12/29 rogid:cn8gYfKDpQc8J2ygnqny32sIyyU9606 rogid:FSPSiiN6YTaETDyAWwAP3wV6zRI9606 rigid:Cnhili6Os5i+9KsmWx3iqclZGC0 false tandem tag:n-n - - - psi-mi:"MI:0658"(multidimensional protein identification technology) psi-mi:"MI:0658"(multidimensional protein identification technology) uniprotkb:P48431 uniprotkb:P39687 intact:EBI-6124081|uniprotkb:Q14537|ensembl:ENSP00000323588 intact:EBI-359234|uniprotkb:Q53FK4|uniprotkb:Q5J8L8|uniprotkb:Q7M4N6|uniprotkb:B2R6T4|ensembl:ENSP00000417864 psi-mi:sox2_human(display_long)|uniprotkb:SOX2(gene name)|psi-mi:SOX2(display_short) psi-mi:an32a_human(display_long)|uniprotkb:ANP32A(gene name)|psi-mi:ANP32A(display_short)|uniprotkb:LANP(gene name synonym)|uniprotkb:PHAP1(gene name synonym)|uniprotkb:C15orf1(gene name synonym)|uniprotkb:MAPM(gene name synonym)|uniprotkb:Potent heat-stable protein phosphatase 2A inhibitor I1PP2A(gene name synonym)|uniprotkb:Acidic nuclear phosphoprotein pp32(gene name synonym)|uniprotkb:Leucine-rich acidic nuclear protein(gene name synonym)|uniprotkb:Putative HLA-DR-associated protein I(gene name synonym)|uniprotkb:Mapmodulin(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Cox et al. (2012) pubmed:23667531|imex:IM-28599 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-26574478|imex:IM-28599-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_003097.1|dip:DIP-59913N|ensembl:ENSG00000181449(gene)|ensembl:ENST00000325404(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001649"(osteoblast differentiation)|go:"GO:0001654"(eye development)|go:"GO:0001714"(endodermal cell fate specification)|go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006325"(chromatin organization)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0009611"(response to wounding)|go:"GO:0009653"(anatomical structure morphogenesis)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0021781"(glial cell fate commitment)|go:"GO:0021983"(pituitary gland development)|go:"GO:0021984"(adenohypophysis development)|go:"GO:0022409"(positive regulation of cell-cell adhesion)|go:"GO:0030154"(cell differentiation)|go:"GO:0030900"(forebrain development)|go:"GO:0035019"(somatic stem cell population maintenance)|go:"GO:0035198"(miRNA binding)|go:"GO:0042246"(tissue regeneration)|go:"GO:0043281"(regulation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0043410"(positive regulation of MAPK cascade)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045165"(cell fate commitment)|go:"GO:0045597"(positive regulation of cell differentiation)|go:"GO:0045665"(negative regulation of neuron differentiation)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048839"(inner ear development)|go:"GO:0050680"(negative regulation of epithelial cell proliferation)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0070848"(response to growth factor)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:0097150"(neuronal stem cell population maintenance)|interpro:IPR009071(High mobility group box, HMG)|interpro:IPR022097|interpro:IPR032643|interpro:IPR036910|mint:P48431|rcsb pdb:1O4X|rcsb pdb:2LE4|rcsb pdb:6T7B|rcsb pdb:6T90|rcsb pdb:6WX7|rcsb pdb:6WX8|rcsb pdb:6WX9|rcsb pdb:6YOV|reactome:R-HSA-2892245|reactome:R-HSA-2892247|reactome:R-HSA-3769402|reactome:R-HSA-452723|reactome:R-HSA-6785807|reactome:R-HSA-8986944 refseq:NP_006296.1|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0006913"(nucleocytoplasmic transport)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0042393"(histone binding)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0048471"(perinuclear region of cytoplasm)|interpro:IPR001611(Leucine-rich repeat)|interpro:IPR003603(U2A'/phosphoprotein 32 family A, C-terminal)|interpro:IPR032675|mint:P39687|rcsb pdb:2JE0|rcsb pdb:2JE1|rcsb pdb:4XOS|rcsb pdb:6XZQ|reactome:R-HSA-450520|ensembl:ENSG00000140350(gene)|ensembl:ENST00000465139(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm) go:"GO:0005634"(nucleus) - - figure legend:ST3 F2C|comment:proteins that were enriched in the induced sample more than 6-fold|dataset:Brain Disease - Neurological Diseases & Disorders|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-daoy)|taxid:9606(Homo sapiens DAOY cerebellar medulloblastoma cell line) - 2020/12/29 2020/12/29 rogid:cn8gYfKDpQc8J2ygnqny32sIyyU9606 rogid:uyR/0ZiQuJsE2V1LbRJQiLs+IH49606 rigid:Cnhili6Os5i+9KsmWx3iqclZGC0 false tandem tag:n-n - - - psi-mi:"MI:0658"(multidimensional protein identification technology) psi-mi:"MI:0658"(multidimensional protein identification technology) uniprotkb:P48431 uniprotkb:Q9NWU2 intact:EBI-6124081|uniprotkb:Q14537|ensembl:ENSP00000323588 intact:EBI-1051077|uniprotkb:Q8N5M5|uniprotkb:E1P5I3|ensembl:ENSP00000266069 psi-mi:sox2_human(display_long)|uniprotkb:SOX2(gene name)|psi-mi:SOX2(display_short) psi-mi:gid8_human(display_long)|uniprotkb:GID8(gene name)|psi-mi:GID8(display_short)|uniprotkb:C20orf11(gene name synonym)|uniprotkb:Two hybrid-associated protein 1 with RanBPM(gene name synonym)|uniprotkb:TWA1(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Cox et al. (2012) pubmed:23667531|imex:IM-28599 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-26574478|imex:IM-28599-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_003097.1|dip:DIP-59913N|ensembl:ENSG00000181449(gene)|ensembl:ENST00000325404(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001649"(osteoblast differentiation)|go:"GO:0001654"(eye development)|go:"GO:0001714"(endodermal cell fate specification)|go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006325"(chromatin organization)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0009611"(response to wounding)|go:"GO:0009653"(anatomical structure morphogenesis)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0021781"(glial cell fate commitment)|go:"GO:0021983"(pituitary gland development)|go:"GO:0021984"(adenohypophysis development)|go:"GO:0022409"(positive regulation of cell-cell adhesion)|go:"GO:0030154"(cell differentiation)|go:"GO:0030900"(forebrain development)|go:"GO:0035019"(somatic stem cell population maintenance)|go:"GO:0035198"(miRNA binding)|go:"GO:0042246"(tissue regeneration)|go:"GO:0043281"(regulation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0043410"(positive regulation of MAPK cascade)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045165"(cell fate commitment)|go:"GO:0045597"(positive regulation of cell differentiation)|go:"GO:0045665"(negative regulation of neuron differentiation)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048839"(inner ear development)|go:"GO:0050680"(negative regulation of epithelial cell proliferation)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0070848"(response to growth factor)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:0097150"(neuronal stem cell population maintenance)|interpro:IPR009071(High mobility group box, HMG)|interpro:IPR022097|interpro:IPR032643|interpro:IPR036910|mint:P48431|rcsb pdb:1O4X|rcsb pdb:2LE4|rcsb pdb:6T7B|rcsb pdb:6T90|rcsb pdb:6WX7|rcsb pdb:6WX8|rcsb pdb:6WX9|rcsb pdb:6YOV|reactome:R-HSA-2892245|reactome:R-HSA-2892247|reactome:R-HSA-3769402|reactome:R-HSA-452723|reactome:R-HSA-6785807|reactome:R-HSA-8986944 refseq:NP_060366.1|ensembl:ENSG00000101193(gene)|ensembl:ENST00000266069(transcript)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0030054"(cell junction)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0090263"(positive regulation of canonical Wnt signaling pathway)|interpro:IPR006594(LisH dimerisation motif)|interpro:IPR006595(CTLH, C-terminal to LisH motif)|interpro:IPR013144(CT11-RanBPM)|interpro:IPR024964|mint:Q9NWU2|rcsb pdb:7NSC go:"GO:0005634"(nucleus) - - figure legend:ST3 F2C|comment:proteins that were enriched in the induced sample more than 6-fold|dataset:Brain Disease - Neurological Diseases & Disorders|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-daoy)|taxid:9606(Homo sapiens DAOY cerebellar medulloblastoma cell line) - 2020/12/29 2020/12/29 rogid:cn8gYfKDpQc8J2ygnqny32sIyyU9606 rogid:P0HsK72KT6OPKKw7lVSJ/FiY4CU9606 rigid:Cnhili6Os5i+9KsmWx3iqclZGC0 false tandem tag:n-n - - - psi-mi:"MI:0658"(multidimensional protein identification technology) psi-mi:"MI:0658"(multidimensional protein identification technology) uniprotkb:P48431 uniprotkb:Q15020 intact:EBI-6124081|uniprotkb:Q14537|ensembl:ENSP00000323588 intact:EBI-308619|uniprotkb:Q2M2H0|uniprotkb:Q58F06|uniprotkb:Q8IUS1|uniprotkb:Q96J95|uniprotkb:A8K2E4|uniprotkb:B7ZKM0|ensembl:ENSP00000449386|intact:EBI-11138149 psi-mi:sox2_human(display_long)|uniprotkb:SOX2(gene name)|psi-mi:SOX2(display_short) psi-mi:sart3_human(display_long)|uniprotkb:KIAA0156(gene name synonym)|uniprotkb:SART3(gene name)|psi-mi:SART3(display_short)|uniprotkb:TIP110(gene name synonym)|uniprotkb:Tat-interacting protein of 110 kDa(gene name synonym)|uniprotkb:p110 nuclear RNA-binding protein(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Cox et al. (2012) pubmed:23667531|imex:IM-28599 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-26574478|imex:IM-28599-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_003097.1|dip:DIP-59913N|ensembl:ENSG00000181449(gene)|ensembl:ENST00000325404(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001649"(osteoblast differentiation)|go:"GO:0001654"(eye development)|go:"GO:0001714"(endodermal cell fate specification)|go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006325"(chromatin organization)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0009611"(response to wounding)|go:"GO:0009653"(anatomical structure morphogenesis)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0021781"(glial cell fate commitment)|go:"GO:0021983"(pituitary gland development)|go:"GO:0021984"(adenohypophysis development)|go:"GO:0022409"(positive regulation of cell-cell adhesion)|go:"GO:0030154"(cell differentiation)|go:"GO:0030900"(forebrain development)|go:"GO:0035019"(somatic stem cell population maintenance)|go:"GO:0035198"(miRNA binding)|go:"GO:0042246"(tissue regeneration)|go:"GO:0043281"(regulation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0043410"(positive regulation of MAPK cascade)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045165"(cell fate commitment)|go:"GO:0045597"(positive regulation of cell differentiation)|go:"GO:0045665"(negative regulation of neuron differentiation)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048839"(inner ear development)|go:"GO:0050680"(negative regulation of epithelial cell proliferation)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0070848"(response to growth factor)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:0097150"(neuronal stem cell population maintenance)|interpro:IPR009071(High mobility group box, HMG)|interpro:IPR022097|interpro:IPR032643|interpro:IPR036910|mint:P48431|rcsb pdb:1O4X|rcsb pdb:2LE4|rcsb pdb:6T7B|rcsb pdb:6T90|rcsb pdb:6WX7|rcsb pdb:6WX8|rcsb pdb:6WX9|rcsb pdb:6YOV|reactome:R-HSA-2892245|reactome:R-HSA-2892247|reactome:R-HSA-3769402|reactome:R-HSA-452723|reactome:R-HSA-6785807|reactome:R-HSA-8986944 ensembl:ENSG00000075856(gene)|ensembl:ENST00000546815(transcript)|go:"GO:0000244"(spliceosomal tri-snRNP complex assembly)|go:"GO:0000387"(spliceosomal snRNP assembly)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0000902"(cell morphogenesis)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006334"(nucleosome assembly)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0015030"(Cajal body)|go:"GO:0016607"(nuclear speck)|go:"GO:0017070"(U6 snRNA binding)|go:"GO:0030621"(U4 snRNA binding)|go:"GO:0030624"(U6atac snRNA binding)|go:"GO:0042393"(histone binding)|go:"GO:0048872"(homeostasis of number of cells)|go:"GO:0061574"(ASAP complex)|go:"GO:0071425"(hematopoietic stem cell proliferation)|go:"GO:1903586"(positive regulation of histone deubiquitination)|go:"GO:1990381"(ubiquitin-specific protease binding)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR003107(RNA-processing protein, HAT helix)|interpro:IPR008669(Lsm interaction)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR034217|interpro:IPR034218|interpro:IPR035979|mint:Q15020|rcsb pdb:2DO4|rcsb pdb:5CTQ|rcsb pdb:5CTR|rcsb pdb:5CTT|rcsb pdb:5JJW|rcsb pdb:5JJX|rcsb pdb:5JPZ|refseq:NP_055521.1 go:"GO:0005634"(nucleus) - - figure legend:ST3 F2C|comment:proteins that were enriched in the induced sample more than 6-fold|dataset:Brain Disease - Neurological Diseases & Disorders|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-daoy)|taxid:9606(Homo sapiens DAOY cerebellar medulloblastoma cell line) - 2020/12/29 2020/12/29 rogid:cn8gYfKDpQc8J2ygnqny32sIyyU9606 rogid:/71mWOMJti/LCvNo2WjCAmIYUCk9606 rigid:Cnhili6Os5i+9KsmWx3iqclZGC0 false tandem tag:n-n - - - psi-mi:"MI:0658"(multidimensional protein identification technology) psi-mi:"MI:0658"(multidimensional protein identification technology) uniprotkb:P48431 uniprotkb:Q01105 intact:EBI-6124081|uniprotkb:Q14537|ensembl:ENSP00000323588 intact:EBI-1053182|uniprotkb:A5A5H4|uniprotkb:Q15541|uniprotkb:Q5VXV1|uniprotkb:Q6FHZ5|intact:EBI-2559610|uniprotkb:A6NGV1|uniprotkb:B4DUE2|intact:EBI-4290953|uniprotkb:Q5VXV2|ensembl:ENSP00000361777 psi-mi:sox2_human(display_long)|uniprotkb:SOX2(gene name)|psi-mi:SOX2(display_short) psi-mi:set_human(display_long)|uniprotkb:Phosphatase 2A inhibitor I2PP2A(gene name synonym)|uniprotkb:Template-activating factor I(gene name synonym)|uniprotkb:HLA-DR-associated protein II(gene name synonym)|uniprotkb:PHAPII(gene name synonym)|uniprotkb:Inhibitor of granzyme A-activated DNase(gene name synonym)|uniprotkb:SET(gene name)|psi-mi:SET(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Cox et al. (2012) pubmed:23667531|imex:IM-28599 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-26574478|imex:IM-28599-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_003097.1|dip:DIP-59913N|ensembl:ENSG00000181449(gene)|ensembl:ENST00000325404(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001649"(osteoblast differentiation)|go:"GO:0001654"(eye development)|go:"GO:0001714"(endodermal cell fate specification)|go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006325"(chromatin organization)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0009611"(response to wounding)|go:"GO:0009653"(anatomical structure morphogenesis)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0021781"(glial cell fate commitment)|go:"GO:0021983"(pituitary gland development)|go:"GO:0021984"(adenohypophysis development)|go:"GO:0022409"(positive regulation of cell-cell adhesion)|go:"GO:0030154"(cell differentiation)|go:"GO:0030900"(forebrain development)|go:"GO:0035019"(somatic stem cell population maintenance)|go:"GO:0035198"(miRNA binding)|go:"GO:0042246"(tissue regeneration)|go:"GO:0043281"(regulation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0043410"(positive regulation of MAPK cascade)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045165"(cell fate commitment)|go:"GO:0045597"(positive regulation of cell differentiation)|go:"GO:0045665"(negative regulation of neuron differentiation)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048839"(inner ear development)|go:"GO:0050680"(negative regulation of epithelial cell proliferation)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0070848"(response to growth factor)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:0097150"(neuronal stem cell population maintenance)|interpro:IPR009071(High mobility group box, HMG)|interpro:IPR022097|interpro:IPR032643|interpro:IPR036910|mint:P48431|rcsb pdb:1O4X|rcsb pdb:2LE4|rcsb pdb:6T7B|rcsb pdb:6T90|rcsb pdb:6WX7|rcsb pdb:6WX8|rcsb pdb:6WX9|rcsb pdb:6YOV|reactome:R-HSA-2892245|reactome:R-HSA-2892247|reactome:R-HSA-3769402|reactome:R-HSA-452723|reactome:R-HSA-6785807|reactome:R-HSA-8986944 refseq:NP_001116293.1|refseq:NP_003002.2|dip:DIP-33561N|refseq:NP_001234930.1|refseq:NP_001234929.1|ensembl:ENSG00000119335(gene)|ensembl:ENST00000372692(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0004864"(protein phosphatase inhibitor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005811"(lipid droplet)|go:"GO:0005829"(cytosol)|go:"GO:0006260"(DNA replication)|go:"GO:0006334"(nucleosome assembly)|go:"GO:0006337"(nucleosome disassembly)|go:"GO:0019888"(protein phosphatase regulator activity)|go:"GO:0032991"(protein-containing complex)|go:"GO:0042393"(histone binding)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0048471"(perinuclear region of cytoplasm)|interpro:IPR002164("Nucleosome assembly protein (NAP)")|interpro:IPR037231|mint:Q01105|rcsb pdb:2E50|rcsb pdb:7MTO|reactome:R-HSA-2299718|reactome:R-HSA-450520|go:"GO:0035067"(negative regulation of histone acetylation) go:"GO:0005634"(nucleus) - - figure legend:ST3 F2C|comment:proteins that were enriched in the induced sample more than 6-fold|dataset:Brain Disease - Neurological Diseases & Disorders|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-daoy)|taxid:9606(Homo sapiens DAOY cerebellar medulloblastoma cell line) - 2020/12/29 2020/12/29 rogid:cn8gYfKDpQc8J2ygnqny32sIyyU9606 rogid:CBwf28rN/LSY/vhw7jxRHKP8q0k9606 rigid:Cnhili6Os5i+9KsmWx3iqclZGC0 false tandem tag:n-n - - - psi-mi:"MI:0658"(multidimensional protein identification technology) psi-mi:"MI:0658"(multidimensional protein identification technology) uniprotkb:P48431 uniprotkb:Q86UP3 intact:EBI-6124081|uniprotkb:Q14537|ensembl:ENSP00000323588 intact:EBI-11317394|uniprotkb:Q6ZN20|uniprotkb:G3V138|uniprotkb:Q18PS0|intact:EBI-28984267 psi-mi:sox2_human(display_long)|uniprotkb:SOX2(gene name)|psi-mi:SOX2(display_short) psi-mi:zfhx4_human(display_long)|uniprotkb:Zinc finger homeodomain protein 4(gene name synonym)|uniprotkb:ZFHX4(gene name)|psi-mi:ZFHX4(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Cox et al. (2012) pubmed:23667531|imex:IM-28599 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-26574571|imex:IM-28599-3 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_003097.1|dip:DIP-59913N|ensembl:ENSG00000181449(gene)|ensembl:ENST00000325404(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001649"(osteoblast differentiation)|go:"GO:0001654"(eye development)|go:"GO:0001714"(endodermal cell fate specification)|go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006325"(chromatin organization)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0009611"(response to wounding)|go:"GO:0009653"(anatomical structure morphogenesis)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0021781"(glial cell fate commitment)|go:"GO:0021983"(pituitary gland development)|go:"GO:0021984"(adenohypophysis development)|go:"GO:0022409"(positive regulation of cell-cell adhesion)|go:"GO:0030154"(cell differentiation)|go:"GO:0030900"(forebrain development)|go:"GO:0035019"(somatic stem cell population maintenance)|go:"GO:0035198"(miRNA binding)|go:"GO:0042246"(tissue regeneration)|go:"GO:0043281"(regulation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0043410"(positive regulation of MAPK cascade)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045165"(cell fate commitment)|go:"GO:0045597"(positive regulation of cell differentiation)|go:"GO:0045665"(negative regulation of neuron differentiation)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048839"(inner ear development)|go:"GO:0050680"(negative regulation of epithelial cell proliferation)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0070848"(response to growth factor)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:0097150"(neuronal stem cell population maintenance)|interpro:IPR009071(High mobility group box, HMG)|interpro:IPR022097|interpro:IPR032643|interpro:IPR036910|mint:P48431|rcsb pdb:1O4X|rcsb pdb:2LE4|rcsb pdb:6T7B|rcsb pdb:6T90|rcsb pdb:6WX7|rcsb pdb:6WX8|rcsb pdb:6WX9|rcsb pdb:6YOV|reactome:R-HSA-2892245|reactome:R-HSA-2892247|reactome:R-HSA-3769402|reactome:R-HSA-452723|reactome:R-HSA-6785807|reactome:R-HSA-8986944 interpro:IPR001356(Homeobox)|interpro:IPR003604(Zinc finger, U1-type)|interpro:IPR009057(Homeodomain-like)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR017970|refseq:NP_078997.4|refseq:XP_011515894.1|refseq:XP_011515895.1|refseq:XP_011515896.1|refseq:XP_011515897.1|mint:Q86UP3|ensembl:ENST00000651372|ensembl:ENSP00000498627|ensembl:ENSG00000091656|interpro:IPR036236|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0008270"(zinc ion binding) go:"GO:0005634"(nucleus) - - figure legend:ST2 F2B|comment:"proteins identified only in induced samples in three MudPIT analyses without BY-adjusted significance (p>0.05), but with t-test significance (p<0.05)"|dataset:Brain Disease - Neurological Diseases & Disorders|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-daoy)|taxid:9606(Homo sapiens DAOY cerebellar medulloblastoma cell line) - 2020/12/29 2020/12/29 rogid:cn8gYfKDpQc8J2ygnqny32sIyyU9606 rogid:YYkSWRGEeD3+KILwMi6LXOWXinA9606 rigid:rcB/+PMkt3xctqX8BtjneHUykZI false tandem tag:n-n - - - psi-mi:"MI:0658"(multidimensional protein identification technology) psi-mi:"MI:0658"(multidimensional protein identification technology) uniprotkb:P48431 uniprotkb:Q9UPU5 intact:EBI-6124081|uniprotkb:Q14537|ensembl:ENSP00000323588 intact:EBI-1642365|uniprotkb:Q6ZSY2|uniprotkb:Q8N2Y4|uniprotkb:Q9NXD1|ensembl:ENSP00000294383 psi-mi:sox2_human(display_long)|uniprotkb:SOX2(gene name)|psi-mi:SOX2(display_short) psi-mi:ubp24_human(display_long)|uniprotkb:USP24(gene name)|psi-mi:USP24(display_short)|uniprotkb:KIAA1057(gene name synonym)|uniprotkb:Ubiquitin-specific-processing protease 24(gene name synonym)|uniprotkb:Deubiquitinating enzyme 24(gene name synonym)|uniprotkb:Ubiquitin thioesterase 24(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Cox et al. (2012) pubmed:23667531|imex:IM-28599 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-26574571|imex:IM-28599-3 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_003097.1|dip:DIP-59913N|ensembl:ENSG00000181449(gene)|ensembl:ENST00000325404(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001649"(osteoblast differentiation)|go:"GO:0001654"(eye development)|go:"GO:0001714"(endodermal cell fate specification)|go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006325"(chromatin organization)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0009611"(response to wounding)|go:"GO:0009653"(anatomical structure morphogenesis)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0021781"(glial cell fate commitment)|go:"GO:0021983"(pituitary gland development)|go:"GO:0021984"(adenohypophysis development)|go:"GO:0022409"(positive regulation of cell-cell adhesion)|go:"GO:0030154"(cell differentiation)|go:"GO:0030900"(forebrain development)|go:"GO:0035019"(somatic stem cell population maintenance)|go:"GO:0035198"(miRNA binding)|go:"GO:0042246"(tissue regeneration)|go:"GO:0043281"(regulation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0043410"(positive regulation of MAPK cascade)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045165"(cell fate commitment)|go:"GO:0045597"(positive regulation of cell differentiation)|go:"GO:0045665"(negative regulation of neuron differentiation)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048839"(inner ear development)|go:"GO:0050680"(negative regulation of epithelial cell proliferation)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0070848"(response to growth factor)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:0097150"(neuronal stem cell population maintenance)|interpro:IPR009071(High mobility group box, HMG)|interpro:IPR022097|interpro:IPR032643|interpro:IPR036910|mint:P48431|rcsb pdb:1O4X|rcsb pdb:2LE4|rcsb pdb:6T7B|rcsb pdb:6T90|rcsb pdb:6WX7|rcsb pdb:6WX8|rcsb pdb:6WX9|rcsb pdb:6YOV|reactome:R-HSA-2892245|reactome:R-HSA-2892247|reactome:R-HSA-3769402|reactome:R-HSA-452723|reactome:R-HSA-6785807|reactome:R-HSA-8986944 ensembl:ENSG00000162402(gene)|ensembl:ENST00000294383(transcript)|go:"GO:0004197"(cysteine-type endopeptidase activity)|go:"GO:0004843"(thiol-dependent deubiquitinase)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0016579"(protein deubiquitination)|interpro:IPR001394(Peptidase C19, ubiquitin carboxyl-terminal hydrolase 2)|interpro:IPR009060(UBA-like)|interpro:IPR015940(Ubiquitin-associated/translation elongation factor EF1B, N-terminal, eukaryote)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR018200|interpro:IPR021905|interpro:IPR028889|refseq:NP_056121.2|interpro:IPR029071|interpro:IPR033382|mint:Q9UPU5|reactome:R-HSA-5689880|interpro:IPR038765 go:"GO:0005634"(nucleus) - - figure legend:ST2 F2B|comment:"proteins identified only in induced samples in three MudPIT analyses without BY-adjusted significance (p>0.05), but with t-test significance (p<0.05)"|dataset:Brain Disease - Neurological Diseases & Disorders|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-daoy)|taxid:9606(Homo sapiens DAOY cerebellar medulloblastoma cell line) - 2020/12/29 2020/12/29 rogid:cn8gYfKDpQc8J2ygnqny32sIyyU9606 rogid:JJq+mHZKczkuP54nocU+Y9HXaQ49606 rigid:rcB/+PMkt3xctqX8BtjneHUykZI false tandem tag:n-n - - - psi-mi:"MI:0658"(multidimensional protein identification technology) psi-mi:"MI:0658"(multidimensional protein identification technology) uniprotkb:P48431 uniprotkb:Q96T58 intact:EBI-6124081|uniprotkb:Q14537|ensembl:ENSP00000323588 intact:EBI-765739|uniprotkb:Q9UQ01|uniprotkb:Q9Y556|uniprotkb:Q9H9A8|uniprotkb:Q9NWH5|intact:EBI-28975565|ensembl:ENSP00000364912 psi-mi:sox2_human(display_long)|uniprotkb:SOX2(gene name)|psi-mi:SOX2(display_short) psi-mi:mint_human(display_long)|uniprotkb:SPEN homolog(gene name synonym)|uniprotkb:SMART/HDAC1-associated repressor protein(gene name synonym)|uniprotkb:KIAA0929(gene name synonym)|uniprotkb:MINT(gene name synonym)|uniprotkb:SHARP(gene name synonym)|uniprotkb:SPEN(gene name)|psi-mi:SPEN(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Cox et al. (2012) pubmed:23667531|imex:IM-28599 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-26574571|imex:IM-28599-3 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_003097.1|dip:DIP-59913N|ensembl:ENSG00000181449(gene)|ensembl:ENST00000325404(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001649"(osteoblast differentiation)|go:"GO:0001654"(eye development)|go:"GO:0001714"(endodermal cell fate specification)|go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006325"(chromatin organization)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0009611"(response to wounding)|go:"GO:0009653"(anatomical structure morphogenesis)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0021781"(glial cell fate commitment)|go:"GO:0021983"(pituitary gland development)|go:"GO:0021984"(adenohypophysis development)|go:"GO:0022409"(positive regulation of cell-cell adhesion)|go:"GO:0030154"(cell differentiation)|go:"GO:0030900"(forebrain development)|go:"GO:0035019"(somatic stem cell population maintenance)|go:"GO:0035198"(miRNA binding)|go:"GO:0042246"(tissue regeneration)|go:"GO:0043281"(regulation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0043410"(positive regulation of MAPK cascade)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045165"(cell fate commitment)|go:"GO:0045597"(positive regulation of cell differentiation)|go:"GO:0045665"(negative regulation of neuron differentiation)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048839"(inner ear development)|go:"GO:0050680"(negative regulation of epithelial cell proliferation)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0070848"(response to growth factor)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:0097150"(neuronal stem cell population maintenance)|interpro:IPR009071(High mobility group box, HMG)|interpro:IPR022097|interpro:IPR032643|interpro:IPR036910|mint:P48431|rcsb pdb:1O4X|rcsb pdb:2LE4|rcsb pdb:6T7B|rcsb pdb:6T90|rcsb pdb:6WX7|rcsb pdb:6WX8|rcsb pdb:6WX9|rcsb pdb:6YOV|reactome:R-HSA-2892245|reactome:R-HSA-2892247|reactome:R-HSA-3769402|reactome:R-HSA-452723|reactome:R-HSA-6785807|reactome:R-HSA-8986944 refseq:NP_055816.2|ensembl:ENSP00000364912|dip:DIP-34569N|ensembl:ENSG00000065526(gene)|ensembl:ENST00000375759(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0003676"(nucleic acid binding)|go:"GO:0003677"(DNA binding)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0050769"(positive regulation of neurogenesis)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:0070062"(extracellular exosome)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR010912(Spen paralogue and orthologue C-terminal, metazoa)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR012921(Spen paralogue and orthologue C-terminal)|interpro:IPR016194(Spen Paralogue and Orthologue C-terminal-like)|interpro:IPR034172|interpro:IPR034173|interpro:IPR034174|interpro:IPR034175|interpro:IPR035979|mint:Q96T58|rcsb pdb:1OW1|rcsb pdb:2RT5|rcsb pdb:4P6Q|reactome:R-HSA-9013422|go:"GO:0005654"(nucleoplasm)|go:"GO:0007219"(Notch signaling pathway)|go:"GO:0017053"(transcription repressor complex)|go:"GO:0045892"(negative regulation of transcription, DNA-templated) go:"GO:0005634"(nucleus) - - figure legend:ST2 F2B|comment:"proteins identified only in induced samples in three MudPIT analyses without BY-adjusted significance (p>0.05), but with t-test significance (p<0.05)"|dataset:Brain Disease - Neurological Diseases & Disorders|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-daoy)|taxid:9606(Homo sapiens DAOY cerebellar medulloblastoma cell line) - 2020/12/29 2020/12/29 rogid:cn8gYfKDpQc8J2ygnqny32sIyyU9606 rogid:m7bdkKVATaG4dkFG/BYXRn4jOIk9606 rigid:rcB/+PMkt3xctqX8BtjneHUykZI false tandem tag:n-n - - - psi-mi:"MI:0658"(multidimensional protein identification technology) psi-mi:"MI:0658"(multidimensional protein identification technology) uniprotkb:P48431 uniprotkb:O15417 intact:EBI-6124081|uniprotkb:Q14537|ensembl:ENSP00000323588 intact:EBI-2824620|uniprotkb:Q96JH1|uniprotkb:A8MX41|uniprotkb:Q96K91|ensembl:ENSP00000395538 psi-mi:sox2_human(display_long)|uniprotkb:SOX2(gene name)|psi-mi:SOX2(display_short) psi-mi:tnc18_human(display_long)|uniprotkb:TNRC18(gene name)|psi-mi:TNRC18(display_short)|uniprotkb:CAGL79(gene name synonym)|uniprotkb:KIAA1856(gene name synonym)|uniprotkb:Long CAG trinucleotide repeat-containing gene 79 protein(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Cox et al. (2012) pubmed:23667531|imex:IM-28599 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-26574571|imex:IM-28599-3 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_003097.1|dip:DIP-59913N|ensembl:ENSG00000181449(gene)|ensembl:ENST00000325404(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001649"(osteoblast differentiation)|go:"GO:0001654"(eye development)|go:"GO:0001714"(endodermal cell fate specification)|go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006325"(chromatin organization)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0009611"(response to wounding)|go:"GO:0009653"(anatomical structure morphogenesis)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0021781"(glial cell fate commitment)|go:"GO:0021983"(pituitary gland development)|go:"GO:0021984"(adenohypophysis development)|go:"GO:0022409"(positive regulation of cell-cell adhesion)|go:"GO:0030154"(cell differentiation)|go:"GO:0030900"(forebrain development)|go:"GO:0035019"(somatic stem cell population maintenance)|go:"GO:0035198"(miRNA binding)|go:"GO:0042246"(tissue regeneration)|go:"GO:0043281"(regulation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0043410"(positive regulation of MAPK cascade)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045165"(cell fate commitment)|go:"GO:0045597"(positive regulation of cell differentiation)|go:"GO:0045665"(negative regulation of neuron differentiation)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048839"(inner ear development)|go:"GO:0050680"(negative regulation of epithelial cell proliferation)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0070848"(response to growth factor)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:0097150"(neuronal stem cell population maintenance)|interpro:IPR009071(High mobility group box, HMG)|interpro:IPR022097|interpro:IPR032643|interpro:IPR036910|mint:P48431|rcsb pdb:1O4X|rcsb pdb:2LE4|rcsb pdb:6T7B|rcsb pdb:6T90|rcsb pdb:6WX7|rcsb pdb:6WX8|rcsb pdb:6WX9|rcsb pdb:6YOV|reactome:R-HSA-2892245|reactome:R-HSA-2892247|reactome:R-HSA-3769402|reactome:R-HSA-452723|reactome:R-HSA-6785807|reactome:R-HSA-8986944 ensembl:ENSP00000395538|ensembl:ENSG00000182095(gene)|ensembl:ENST00000430969(transcript)|go:"GO:0003682"(chromatin binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0031965"(nuclear membrane)|interpro:IPR001025(Bromo adjacent region)|interpro:IPR043151|mint:O15417|refseq:NP_001073964.2 go:"GO:0005634"(nucleus) - - figure legend:ST2 F2B|comment:"proteins identified only in induced samples in three MudPIT analyses without BY-adjusted significance (p>0.05), but with t-test significance (p<0.05)"|dataset:Brain Disease - Neurological Diseases & Disorders|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-daoy)|taxid:9606(Homo sapiens DAOY cerebellar medulloblastoma cell line) - 2020/12/29 2020/12/29 rogid:cn8gYfKDpQc8J2ygnqny32sIyyU9606 rogid:fz8Icir2kPLN94mzdd5YLz22I4c9606 rigid:rcB/+PMkt3xctqX8BtjneHUykZI false tandem tag:n-n - - - psi-mi:"MI:0658"(multidimensional protein identification technology) psi-mi:"MI:0658"(multidimensional protein identification technology) uniprotkb:P48431 uniprotkb:Q9UQE7 intact:EBI-6124081|uniprotkb:Q14537|ensembl:ENSP00000323588 intact:EBI-80718|ensembl:ENSP00000354720|uniprotkb:O60464|uniprotkb:Q5T482|uniprotkb:A8K156 psi-mi:sox2_human(display_long)|uniprotkb:SOX2(gene name)|psi-mi:SOX2(display_short) psi-mi:smc3_human(display_long)|uniprotkb:SMC3(gene name)|psi-mi:SMC3(display_short)|uniprotkb:BAM(gene name synonym)|uniprotkb:SMC3L1(gene name synonym)|uniprotkb:Chondroitin sulfate proteoglycan 6(gene name synonym)|uniprotkb:Chromosome-associated polypeptide(gene name synonym)|uniprotkb:Basement membrane-associated chondroitin proteoglycan(gene name synonym)|uniprotkb:BMH(gene name synonym)|uniprotkb:CSPG6(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Cox et al. (2012) pubmed:23667531|imex:IM-28599 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-26574571|imex:IM-28599-3 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_003097.1|dip:DIP-59913N|ensembl:ENSG00000181449(gene)|ensembl:ENST00000325404(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001649"(osteoblast differentiation)|go:"GO:0001654"(eye development)|go:"GO:0001714"(endodermal cell fate specification)|go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006325"(chromatin organization)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0009611"(response to wounding)|go:"GO:0009653"(anatomical structure morphogenesis)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0021781"(glial cell fate commitment)|go:"GO:0021983"(pituitary gland development)|go:"GO:0021984"(adenohypophysis development)|go:"GO:0022409"(positive regulation of cell-cell adhesion)|go:"GO:0030154"(cell differentiation)|go:"GO:0030900"(forebrain development)|go:"GO:0035019"(somatic stem cell population maintenance)|go:"GO:0035198"(miRNA binding)|go:"GO:0042246"(tissue regeneration)|go:"GO:0043281"(regulation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0043410"(positive regulation of MAPK cascade)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045165"(cell fate commitment)|go:"GO:0045597"(positive regulation of cell differentiation)|go:"GO:0045665"(negative regulation of neuron differentiation)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048839"(inner ear development)|go:"GO:0050680"(negative regulation of epithelial cell proliferation)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0070848"(response to growth factor)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:0097150"(neuronal stem cell population maintenance)|interpro:IPR009071(High mobility group box, HMG)|interpro:IPR022097|interpro:IPR032643|interpro:IPR036910|mint:P48431|rcsb pdb:1O4X|rcsb pdb:2LE4|rcsb pdb:6T7B|rcsb pdb:6T90|rcsb pdb:6WX7|rcsb pdb:6WX8|rcsb pdb:6WX9|rcsb pdb:6YOV|reactome:R-HSA-2892245|reactome:R-HSA-2892247|reactome:R-HSA-3769402|reactome:R-HSA-452723|reactome:R-HSA-6785807|reactome:R-HSA-8986944 go:"GO:0090307"(mitotic spindle assembly)|go:"GO:0097431"(mitotic spindle pole)|interpro:IPR003395(RecF/RecN/SMC protein, N-terminal)|interpro:IPR010935(SMCs flexible hinge)|interpro:IPR024704|interpro:IPR027417|interpro:IPR036277|interpro:IPR041741|mint:Q9UQE7|rcsb pdb:6WG3|rcsb pdb:6WG4|rcsb pdb:6WG6|rcsb pdb:6WGE|reactome:R-HSA-1221632|reactome:R-HSA-2467813|reactome:R-HSA-2468052|reactome:R-HSA-2470946|reactome:R-HSA-2500257|reactome:R-HSA-3108214|reactome:R-HSA-9018519|go:"GO:0070840"(dynein complex binding)|ensembl:ENSG00000108055(gene)|ensembl:ENST00000361804(transcript)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0000775"(chromosome, centromeric region)|go:"GO:0000785"(chromatin)|go:"GO:0000800"(lateral element)|go:"GO:0003682"(chromatin binding)|go:"GO:0003777"(microtubule motor activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005694"(chromosome)|go:"GO:0005829"(cytosol)|go:"GO:0006275"(regulation of DNA replication)|go:"GO:0006281"(DNA repair)|go:"GO:0007062"(sister chromatid cohesion)|go:"GO:0008278"(cohesin complex)|go:"GO:0016363"(nuclear matrix)|go:"GO:0019827"(stem cell population maintenance)|go:"GO:0030893"(meiotic cohesin complex)|go:"GO:0034991"(nuclear meiotic cohesin complex)|go:"GO:0036033"(mediator complex binding)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0048487"(beta-tubulin binding)|go:"GO:0051301"(cell division)|go:"GO:0051321"(meiotic cell cycle)|refseq:NP_005436.1|dip:DIP-29200N go:"GO:0005634"(nucleus) - - figure legend:ST2 F2B|comment:"proteins identified only in induced samples in three MudPIT analyses without BY-adjusted significance (p>0.05), but with t-test significance (p<0.05)"|dataset:Brain Disease - Neurological Diseases & Disorders|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-daoy)|taxid:9606(Homo sapiens DAOY cerebellar medulloblastoma cell line) - 2020/12/29 2020/12/29 rogid:cn8gYfKDpQc8J2ygnqny32sIyyU9606 rogid:pUxr+sTtttRzGlqCRz/25woNtrg9606 rigid:rcB/+PMkt3xctqX8BtjneHUykZI false tandem tag:n-n - - - psi-mi:"MI:0658"(multidimensional protein identification technology) psi-mi:"MI:0658"(multidimensional protein identification technology) uniprotkb:P48431 uniprotkb:Q96L91 intact:EBI-6124081|uniprotkb:Q14537|ensembl:ENSP00000323588 intact:EBI-399163|uniprotkb:O15411|uniprotkb:Q6P2F5|uniprotkb:Q8N8Q7|uniprotkb:Q8NE05|uniprotkb:Q96JK7|uniprotkb:Q9P230 psi-mi:sox2_human(display_long)|uniprotkb:SOX2(gene name)|psi-mi:SOX2(display_short) psi-mi:ep400_human(display_long)|uniprotkb:p400 kDa SWI2/SNF2-related protein(gene name synonym)|uniprotkb:Domino homolog(gene name synonym)|uniprotkb:CAG repeat protein 32(gene name synonym)|uniprotkb:Trinucleotide repeat-containing gene 12 protein(gene name synonym)|uniprotkb:CAGH32(gene name synonym)|uniprotkb:KIAA1498(gene name synonym)|uniprotkb:KIAA1818(gene name synonym)|uniprotkb:TNRC12(gene name synonym)|uniprotkb:EP400(gene name)|psi-mi:EP400(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Cox et al. (2012) pubmed:23667531|imex:IM-28599 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-26574571|imex:IM-28599-3 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_003097.1|dip:DIP-59913N|ensembl:ENSG00000181449(gene)|ensembl:ENST00000325404(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001649"(osteoblast differentiation)|go:"GO:0001654"(eye development)|go:"GO:0001714"(endodermal cell fate specification)|go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006325"(chromatin organization)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0009611"(response to wounding)|go:"GO:0009653"(anatomical structure morphogenesis)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0021781"(glial cell fate commitment)|go:"GO:0021983"(pituitary gland development)|go:"GO:0021984"(adenohypophysis development)|go:"GO:0022409"(positive regulation of cell-cell adhesion)|go:"GO:0030154"(cell differentiation)|go:"GO:0030900"(forebrain development)|go:"GO:0035019"(somatic stem cell population maintenance)|go:"GO:0035198"(miRNA binding)|go:"GO:0042246"(tissue regeneration)|go:"GO:0043281"(regulation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0043410"(positive regulation of MAPK cascade)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045165"(cell fate commitment)|go:"GO:0045597"(positive regulation of cell differentiation)|go:"GO:0045665"(negative regulation of neuron differentiation)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048839"(inner ear development)|go:"GO:0050680"(negative regulation of epithelial cell proliferation)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0070848"(response to growth factor)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:0097150"(neuronal stem cell population maintenance)|interpro:IPR009071(High mobility group box, HMG)|interpro:IPR022097|interpro:IPR032643|interpro:IPR036910|mint:P48431|rcsb pdb:1O4X|rcsb pdb:2LE4|rcsb pdb:6T7B|rcsb pdb:6T90|rcsb pdb:6WX7|rcsb pdb:6WX8|rcsb pdb:6WX9|rcsb pdb:6YOV|reactome:R-HSA-2892245|reactome:R-HSA-2892247|reactome:R-HSA-3769402|reactome:R-HSA-452723|reactome:R-HSA-6785807|reactome:R-HSA-8986944 refseq:NP_056224.3|ensembl:ENST00000389561|ensembl:ENSP00000374212|ensembl:ENSG00000183495|go:"GO:0000812"(Swr1 complex)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0004386"(helicase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0016607"(nuclear speck)|go:"GO:0016787"(hydrolase activity)|go:"GO:0035267"(NuA4 histone acetyltransferase complex)|go:"GO:0043967"(histone H4 acetylation)|go:"GO:0043968"(histone H2A acetylation)|go:"GO:0070615"|go:"GO:1990405"(protein antigen binding)|interpro:IPR000330(SNF2-related)|interpro:IPR001005(SANT, DNA-binding)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR014012(Helicase/SANT-associated, DNA binding)|interpro:IPR027417|interpro:IPR031575|interpro:IPR038718|reactome:R-HSA-2559584|reactome:R-HSA-2559586|reactome:R-HSA-3214847|mint:Q96L91|dip:DIP-29915N go:"GO:0005634"(nucleus) - - figure legend:ST2 F2B|comment:"proteins identified only in induced samples in three MudPIT analyses without BY-adjusted significance (p>0.05), but with t-test significance (p<0.05)"|dataset:Brain Disease - Neurological Diseases & Disorders|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-daoy)|taxid:9606(Homo sapiens DAOY cerebellar medulloblastoma cell line) - 2020/12/29 2020/12/29 rogid:cn8gYfKDpQc8J2ygnqny32sIyyU9606 rogid:DrQFsyaSlUxjJBloZPFrjXooDpU9606 rigid:rcB/+PMkt3xctqX8BtjneHUykZI false tandem tag:n-n - - - psi-mi:"MI:0658"(multidimensional protein identification technology) psi-mi:"MI:0658"(multidimensional protein identification technology) uniprotkb:P48431 uniprotkb:O75376 intact:EBI-6124081|uniprotkb:Q14537|ensembl:ENSP00000323588 intact:EBI-347233|uniprotkb:E9PGV6|uniprotkb:Q86YY0|uniprotkb:Q9UPV5|uniprotkb:Q9UQ18|intact:EBI-28976482|ensembl:ENSP00000268712|uniprotkb:B3DLF8 psi-mi:sox2_human(display_long)|uniprotkb:SOX2(gene name)|psi-mi:SOX2(display_short) psi-mi:ncor1_human(display_long)|uniprotkb:NCOR1(gene name)|psi-mi:NCOR1(display_short)|uniprotkb:KIAA1047(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Cox et al. (2012) pubmed:23667531|imex:IM-28599 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-26574571|imex:IM-28599-3 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_003097.1|dip:DIP-59913N|ensembl:ENSG00000181449(gene)|ensembl:ENST00000325404(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001649"(osteoblast differentiation)|go:"GO:0001654"(eye development)|go:"GO:0001714"(endodermal cell fate specification)|go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006325"(chromatin organization)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0009611"(response to wounding)|go:"GO:0009653"(anatomical structure morphogenesis)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0021781"(glial cell fate commitment)|go:"GO:0021983"(pituitary gland development)|go:"GO:0021984"(adenohypophysis development)|go:"GO:0022409"(positive regulation of cell-cell adhesion)|go:"GO:0030154"(cell differentiation)|go:"GO:0030900"(forebrain development)|go:"GO:0035019"(somatic stem cell population maintenance)|go:"GO:0035198"(miRNA binding)|go:"GO:0042246"(tissue regeneration)|go:"GO:0043281"(regulation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0043410"(positive regulation of MAPK cascade)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045165"(cell fate commitment)|go:"GO:0045597"(positive regulation of cell differentiation)|go:"GO:0045665"(negative regulation of neuron differentiation)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048839"(inner ear development)|go:"GO:0050680"(negative regulation of epithelial cell proliferation)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0070848"(response to growth factor)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:0097150"(neuronal stem cell population maintenance)|interpro:IPR009071(High mobility group box, HMG)|interpro:IPR022097|interpro:IPR032643|interpro:IPR036910|mint:P48431|rcsb pdb:1O4X|rcsb pdb:2LE4|rcsb pdb:6T7B|rcsb pdb:6T90|rcsb pdb:6WX7|rcsb pdb:6WX8|rcsb pdb:6WX9|rcsb pdb:6YOV|reactome:R-HSA-2892245|reactome:R-HSA-2892247|reactome:R-HSA-3769402|reactome:R-HSA-452723|reactome:R-HSA-6785807|reactome:R-HSA-8986944 dip:DIP-29402N|ensembl:ENSP00000268712|ensembl:ENST00000395848|ensembl:ENSP00000379189|ensembl:ENST00000395851|ensembl:ENSP00000379192|ensembl:ENSG00000141027(gene)|ensembl:ENST00000268712(transcript)|go:"GO:0000118"(histone deacetylase complex)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006325"(chromatin organization)|go:"GO:0016020"(membrane)|go:"GO:0016922"(nuclear receptor binding)|go:"GO:0017053"(transcription repressor complex)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0045475"(locomotor rhythm)|go:"GO:0045820"(negative regulation of glycolytic process)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045922"(negative regulation of fatty acid metabolic process)|go:"GO:0046329"(negative regulation of JNK cascade)|go:"GO:0046966"(thyroid hormone receptor binding)|go:"GO:0051225"(spindle assembly)|go:"GO:0060766"(negative regulation of androgen receptor signaling pathway)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:0072686"(mitotic spindle)|go:"GO:1903799"(negative regulation of production of miRNAs involved in gene silencing by miRNA)|interpro:IPR001005(SANT, DNA-binding)|interpro:IPR009057(Homeodomain-like)|interpro:IPR017884|interpro:IPR017930|interpro:IPR031557|mint:O75376|rcsb pdb:2EQR|rcsb pdb:3KMZ|rcsb pdb:3N00|rcsb pdb:4MDD|rcsb pdb:4WVD|rcsb pdb:6ONI|rcsb pdb:6WMQ|rcsb pdb:6XXS|rcsb pdb:6XYX|rcsb pdb:6XZZ|rcsb pdb:6Y17|rcsb pdb:6ZBU|reactome:R-HSA-1251985|reactome:R-HSA-1368071|reactome:R-HSA-1989781|reactome:R-HSA-2122947|reactome:R-HSA-2151201|reactome:R-HSA-2173795|reactome:R-HSA-2644606|rcsb pdb:3H52|reactome:R-HSA-2894862|reactome:R-HSA-3214815|reactome:R-HSA-350054|reactome:R-HSA-381340|reactome:R-HSA-383280|reactome:R-HSA-400206|reactome:R-HSA-400253|reactome:R-HSA-5617472|reactome:R-HSA-9022537|reactome:R-HSA-9022692|reactome:R-HSA-9029569|reactome:R-HSA-9609690|reactome:R-HSA-9623433|reactome:R-HSA-9707564|reactome:R-HSA-9707616|refseq:XP_011522388.1|refseq:NP_001177369.1|refseq:NP_006302.2|refseq:NP_001177367.1 go:"GO:0005634"(nucleus) - - figure legend:ST2 F2B|comment:"proteins identified only in induced samples in three MudPIT analyses without BY-adjusted significance (p>0.05), but with t-test significance (p<0.05)"|dataset:Brain Disease - Neurological Diseases & Disorders|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-daoy)|taxid:9606(Homo sapiens DAOY cerebellar medulloblastoma cell line) - 2020/12/29 2020/12/29 rogid:cn8gYfKDpQc8J2ygnqny32sIyyU9606 rogid:8W82xLRBbuJwVpXSvxoGQBu0v7Y9606 rigid:rcB/+PMkt3xctqX8BtjneHUykZI false tandem tag:n-n - - - psi-mi:"MI:0658"(multidimensional protein identification technology) psi-mi:"MI:0658"(multidimensional protein identification technology) uniprotkb:P48431 uniprotkb:Q12873 intact:EBI-6124081|uniprotkb:Q14537|ensembl:ENSP00000323588 intact:EBI-523590|uniprotkb:Q9Y4I0|intact:EBI-28978117|ensembl:ENSP00000332628|uniprotkb:D3DTQ9|uniprotkb:E9PG89 psi-mi:sox2_human(display_long)|uniprotkb:SOX2(gene name)|psi-mi:SOX2(display_short) psi-mi:chd3_human(display_long)|uniprotkb:ATP-dependent helicase CHD3(gene name synonym)|uniprotkb:Mi-2 autoantigen 240 kDa protein(gene name synonym)|uniprotkb:Mi2-alpha(gene name synonym)|uniprotkb:Zinc finger helicase(gene name synonym)|uniprotkb:CHD3(gene name)|psi-mi:CHD3(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Cox et al. (2012) pubmed:23667531|imex:IM-28599 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-26574571|imex:IM-28599-3 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_003097.1|dip:DIP-59913N|ensembl:ENSG00000181449(gene)|ensembl:ENST00000325404(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001649"(osteoblast differentiation)|go:"GO:0001654"(eye development)|go:"GO:0001714"(endodermal cell fate specification)|go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006325"(chromatin organization)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0009611"(response to wounding)|go:"GO:0009653"(anatomical structure morphogenesis)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0021781"(glial cell fate commitment)|go:"GO:0021983"(pituitary gland development)|go:"GO:0021984"(adenohypophysis development)|go:"GO:0022409"(positive regulation of cell-cell adhesion)|go:"GO:0030154"(cell differentiation)|go:"GO:0030900"(forebrain development)|go:"GO:0035019"(somatic stem cell population maintenance)|go:"GO:0035198"(miRNA binding)|go:"GO:0042246"(tissue regeneration)|go:"GO:0043281"(regulation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0043410"(positive regulation of MAPK cascade)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045165"(cell fate commitment)|go:"GO:0045597"(positive regulation of cell differentiation)|go:"GO:0045665"(negative regulation of neuron differentiation)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048839"(inner ear development)|go:"GO:0050680"(negative regulation of epithelial cell proliferation)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0070848"(response to growth factor)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:0097150"(neuronal stem cell population maintenance)|interpro:IPR009071(High mobility group box, HMG)|interpro:IPR022097|interpro:IPR032643|interpro:IPR036910|mint:P48431|rcsb pdb:1O4X|rcsb pdb:2LE4|rcsb pdb:6T7B|rcsb pdb:6T90|rcsb pdb:6WX7|rcsb pdb:6WX8|rcsb pdb:6WX9|rcsb pdb:6YOV|reactome:R-HSA-2892245|reactome:R-HSA-2892247|reactome:R-HSA-3769402|reactome:R-HSA-452723|reactome:R-HSA-6785807|reactome:R-HSA-8986944 interpro:IPR023780|interpro:IPR027417|interpro:IPR036910|interpro:IPR038718|mint:Q12873|reactome:R-HSA-3214815|reactome:R-HSA-427389|reactome:R-HSA-4551638|reactome:R-HSA-6804758|reactome:R-HSA-73762|reactome:R-HSA-8943724|reactome:R-HSA-9679191|ensembl:ENSG00000170004(gene)|ensembl:ENST00000330494(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0003677"(DNA binding)|go:"GO:0003678"(DNA helicase activity)|go:"GO:0003723"(RNA binding)|go:"GO:0004386"(helicase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0006333"(chromatin assembly or disassembly)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007051"(spindle organization)|go:"GO:0007098"(centrosome cycle)|go:"GO:0008270"(zinc ion binding)|go:"GO:0016581"(NuRD complex)|go:"GO:0016605"(PML body)|go:"GO:0034451"(centriolar satellite)|go:"GO:0036121"(double-stranded DNA helicase activity)|go:"GO:0043044"|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|interpro:IPR012957(CHD, C-terminal 2)|interpro:IPR012958(CHD, N-terminal)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR016197(Chromo domain-like)|interpro:IPR019786|go:"GO:0070615"|interpro:IPR019787|interpro:IPR023779|go:"GO:0140603"(obsolete ATP hydrolysis activity)|interpro:IPR000330(SNF2-related)|interpro:IPR000953(Chromo domain)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR001965(Zinc finger, PHD-type)|interpro:IPR002464(DNA/RNA helicase, ATP-dependent, DEAH-box type, conserved site)|interpro:IPR009462(Protein of unknown function DUF1086)|interpro:IPR009463(Protein of unknown function DUF1087)|ensembl:ENSP00000332628|ensembl:ENST00000358181|ensembl:ENSP00000350907|ensembl:ENST00000380358|ensembl:ENSP00000369716|refseq:NP_001005271.2|refseq:NP_001005273.1|refseq:NP_005843.2|dip:DIP-32496N go:"GO:0005634"(nucleus) - - figure legend:ST2 F2B|comment:"proteins identified only in induced samples in three MudPIT analyses without BY-adjusted significance (p>0.05), but with t-test significance (p<0.05)"|dataset:Brain Disease - Neurological Diseases & Disorders|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-daoy)|taxid:9606(Homo sapiens DAOY cerebellar medulloblastoma cell line) - 2020/12/29 2020/12/29 rogid:cn8gYfKDpQc8J2ygnqny32sIyyU9606 rogid:UjefFUXiV28qhOP9BoIUansxl+k9606 rigid:rcB/+PMkt3xctqX8BtjneHUykZI false tandem tag:n-n - - - psi-mi:"MI:0658"(multidimensional protein identification technology) psi-mi:"MI:0658"(multidimensional protein identification technology) uniprotkb:P48431 uniprotkb:Q9BYW2 intact:EBI-6124081|uniprotkb:Q14537|ensembl:ENSP00000323588 intact:EBI-945869|uniprotkb:O75397|uniprotkb:O75405|uniprotkb:Q17RW8|uniprotkb:Q5BKS9|uniprotkb:Q5QGN2|uniprotkb:Q69YI5|uniprotkb:Q6IN64|uniprotkb:Q6ZN53|uniprotkb:Q6ZS25|uniprotkb:Q8N3R0|uniprotkb:Q8TCN0|uniprotkb:Q9C0D1|uniprotkb:Q9H696|uniprotkb:Q9NZW9|ensembl:ENSP00000386759 psi-mi:sox2_human(display_long)|uniprotkb:SOX2(gene name)|psi-mi:SOX2(display_short) psi-mi:setd2_human(display_long)|uniprotkb:Protein-lysine N-methyltransferase SETD2(gene name synonym)|uniprotkb:KMT3A(gene name synonym)|uniprotkb:SET domain-containing protein 2(gene name synonym)|uniprotkb:Huntingtin-interacting protein B(gene name synonym)|uniprotkb:Huntingtin yeast partner B(gene name synonym)|uniprotkb:Huntingtin-interacting protein 1(gene name synonym)|uniprotkb:HIF-1(gene name synonym)|uniprotkb:p231HBP(gene name synonym)|uniprotkb:Lysine N-methyltransferase 3A(gene name synonym)|uniprotkb:SETD2(gene name)|psi-mi:SETD2(display_short)|uniprotkb:HIF1(gene name synonym)|uniprotkb:HYPB(gene name synonym)|uniprotkb:KIAA1732(gene name synonym)|uniprotkb:SET2(gene name synonym)|uniprotkb:HSPC069(orf name) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Cox et al. (2012) pubmed:23667531|imex:IM-28599 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-26574571|imex:IM-28599-3 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_003097.1|dip:DIP-59913N|ensembl:ENSG00000181449(gene)|ensembl:ENST00000325404(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001649"(osteoblast differentiation)|go:"GO:0001654"(eye development)|go:"GO:0001714"(endodermal cell fate specification)|go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006325"(chromatin organization)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0009611"(response to wounding)|go:"GO:0009653"(anatomical structure morphogenesis)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0021781"(glial cell fate commitment)|go:"GO:0021983"(pituitary gland development)|go:"GO:0021984"(adenohypophysis development)|go:"GO:0022409"(positive regulation of cell-cell adhesion)|go:"GO:0030154"(cell differentiation)|go:"GO:0030900"(forebrain development)|go:"GO:0035019"(somatic stem cell population maintenance)|go:"GO:0035198"(miRNA binding)|go:"GO:0042246"(tissue regeneration)|go:"GO:0043281"(regulation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0043410"(positive regulation of MAPK cascade)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045165"(cell fate commitment)|go:"GO:0045597"(positive regulation of cell differentiation)|go:"GO:0045665"(negative regulation of neuron differentiation)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048839"(inner ear development)|go:"GO:0050680"(negative regulation of epithelial cell proliferation)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0070848"(response to growth factor)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:0097150"(neuronal stem cell population maintenance)|interpro:IPR009071(High mobility group box, HMG)|interpro:IPR022097|interpro:IPR032643|interpro:IPR036910|mint:P48431|rcsb pdb:1O4X|rcsb pdb:2LE4|rcsb pdb:6T7B|rcsb pdb:6T90|rcsb pdb:6WX7|rcsb pdb:6WX8|rcsb pdb:6WX9|rcsb pdb:6YOV|reactome:R-HSA-2892245|reactome:R-HSA-2892247|reactome:R-HSA-3769402|reactome:R-HSA-452723|reactome:R-HSA-6785807|reactome:R-HSA-8986944 refseq:NP_054878.5|ensembl:ENSG00000181555(gene)|ensembl:ENST00000409792(transcript)|go:"GO:0001525"(angiogenesis)|go:"GO:0001763"(morphogenesis of a branching structure)|go:"GO:0001843"(neural tube closure)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005694"(chromosome)|go:"GO:0006298"(mismatch repair)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006368"(transcription elongation from RNA polymerase II promoter)|go:"GO:0010569"(regulation of double-strand break repair via homologous recombination)|go:"GO:0010793"(regulation of mRNA export from nucleus)|go:"GO:0016279"(protein-lysine N-methyltransferase activity)|go:"GO:0018023"(peptidyl-lysine trimethylation)|go:"GO:0018024"(histone-lysine N-methyltransferase activity)|go:"GO:0018026"(peptidyl-lysine monomethylation)|go:"GO:0030900"(forebrain development)|go:"GO:0032465"(regulation of cytokinesis)|go:"GO:0032727"(positive regulation of interferon-alpha production)|go:"GO:0034340"(response to type I interferon)|go:"GO:0034728"(nucleosome organization)|go:"GO:0035441"(cell migration involved in vasculogenesis)|go:"GO:0035987"(endodermal cell differentiation)|go:"GO:0043014"(alpha-tubulin binding)|go:"GO:0046872"(metal ion binding)|go:"GO:0046975"("histone methyltransferase activity (H3-K36 specific)")|go:"GO:0048332"(mesoderm morphogenesis)|go:"GO:0048701"(embryonic cranial skeleton morphogenesis)|go:"GO:0048863"(stem cell differentiation)|go:"GO:0048864"(stem cell development)|go:"GO:0051607"(defense response to virus)|go:"GO:0060039"(pericardium development)|go:"GO:0060669"(embryonic placenta morphogenesis)|go:"GO:0060977"(coronary vasculature morphogenesis)|go:"GO:0097198"(histone H3-K36 trimethylation)|go:"GO:0097676"(histone H3-K36 dimethylation)|go:"GO:1902850"(microtubule cytoskeleton organization involved in mitosis)|go:"GO:1905634"(regulation of protein localization to chromatin)|interpro:IPR001202(WW/Rsp5/WWP)|interpro:IPR001214(SET)|interpro:IPR003616(Post-SET zinc-binding region)|interpro:IPR006560(AWS)|interpro:IPR013257(SRI, Set2 Rpb1 interacting)|interpro:IPR035441|interpro:IPR036020|interpro:IPR038190|interpro:IPR042294|interpro:IPR044437|mint:Q9BYW2|rcsb pdb:2A7O|rcsb pdb:2MDC|rcsb pdb:2MDI|rcsb pdb:2MDJ|rcsb pdb:4FMU|rcsb pdb:4H12|rcsb pdb:5JJY|rcsb pdb:5JLB|rcsb pdb:5JLE|rcsb pdb:5LSS|rcsb pdb:5LSX|rcsb pdb:5LSY|rcsb pdb:5LSZ|rcsb pdb:5LT6|rcsb pdb:5LT7|rcsb pdb:5LT8|rcsb pdb:5V21|rcsb pdb:5V22|rcsb pdb:6J9J|rcsb pdb:6VDB|reactome:R-HSA-3214841 go:"GO:0005634"(nucleus) - - figure legend:ST2 F2B|comment:"proteins identified only in induced samples in three MudPIT analyses without BY-adjusted significance (p>0.05), but with t-test significance (p<0.05)"|dataset:Brain Disease - Neurological Diseases & Disorders|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-daoy)|taxid:9606(Homo sapiens DAOY cerebellar medulloblastoma cell line) - 2020/12/29 2020/12/29 rogid:cn8gYfKDpQc8J2ygnqny32sIyyU9606 rogid:9f0NjyLj+lCSDh5yRP9lVMMepuw9606 rigid:rcB/+PMkt3xctqX8BtjneHUykZI false tandem tag:n-n - - - psi-mi:"MI:0658"(multidimensional protein identification technology) psi-mi:"MI:0658"(multidimensional protein identification technology) uniprotkb:P48431 uniprotkb:Q9H582 intact:EBI-6124081|uniprotkb:Q14537|ensembl:ENSP00000323588 intact:EBI-2560435|uniprotkb:Q7LG67|uniprotkb:Q5TCC0|uniprotkb:Q6PI06|uniprotkb:Q9ULJ9|uniprotkb:A2RU71|uniprotkb:Q2TAM0|uniprotkb:Q6P446|uniprotkb:Q6BEP7|ensembl:ENSP00000337008|ensembl:ENSP00000359469 psi-mi:sox2_human(display_long)|uniprotkb:SOX2(gene name)|psi-mi:SOX2(display_short) psi-mi:zn644_human(display_long)|uniprotkb:ZNF644(gene name)|psi-mi:ZNF644(display_short)|uniprotkb:KIAA1221(gene name synonym)|uniprotkb:ZEP2(gene name synonym)|uniprotkb:Zinc finger motif enhancer-binding protein 2(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Cox et al. (2012) pubmed:23667531|imex:IM-28599 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-26574571|imex:IM-28599-3 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_003097.1|dip:DIP-59913N|ensembl:ENSG00000181449(gene)|ensembl:ENST00000325404(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001649"(osteoblast differentiation)|go:"GO:0001654"(eye development)|go:"GO:0001714"(endodermal cell fate specification)|go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006325"(chromatin organization)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0009611"(response to wounding)|go:"GO:0009653"(anatomical structure morphogenesis)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0021781"(glial cell fate commitment)|go:"GO:0021983"(pituitary gland development)|go:"GO:0021984"(adenohypophysis development)|go:"GO:0022409"(positive regulation of cell-cell adhesion)|go:"GO:0030154"(cell differentiation)|go:"GO:0030900"(forebrain development)|go:"GO:0035019"(somatic stem cell population maintenance)|go:"GO:0035198"(miRNA binding)|go:"GO:0042246"(tissue regeneration)|go:"GO:0043281"(regulation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0043410"(positive regulation of MAPK cascade)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045165"(cell fate commitment)|go:"GO:0045597"(positive regulation of cell differentiation)|go:"GO:0045665"(negative regulation of neuron differentiation)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048839"(inner ear development)|go:"GO:0050680"(negative regulation of epithelial cell proliferation)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0070848"(response to growth factor)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:0097150"(neuronal stem cell population maintenance)|interpro:IPR009071(High mobility group box, HMG)|interpro:IPR022097|interpro:IPR032643|interpro:IPR036910|mint:P48431|rcsb pdb:1O4X|rcsb pdb:2LE4|rcsb pdb:6T7B|rcsb pdb:6T90|rcsb pdb:6WX7|rcsb pdb:6WX8|rcsb pdb:6WX9|rcsb pdb:6YOV|reactome:R-HSA-2892245|reactome:R-HSA-2892247|reactome:R-HSA-3769402|reactome:R-HSA-452723|reactome:R-HSA-6785807|reactome:R-HSA-8986944 refseq:NP_057704.2|refseq:NP_115562.3|refseq:NP_958357.1|refseq:XP_016857977.1|refseq:XP_016857978.1|refseq:XP_016857979.1|refseq:XP_016857980.1|refseq:XP_016857981.1|refseq:XP_016857982.1|refseq:XP_016857983.1|ensembl:ENSG00000122482(gene)|ensembl:ENST00000337393(transcript)|ensembl:ENST00000370440(transcript)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001222"(transcription corepressor binding)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR036236|mint:Q9H582 go:"GO:0005634"(nucleus) - - figure legend:ST2 F2B|comment:"proteins identified only in induced samples in three MudPIT analyses without BY-adjusted significance (p>0.05), but with t-test significance (p<0.05)"|dataset:Brain Disease - Neurological Diseases & Disorders|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-daoy)|taxid:9606(Homo sapiens DAOY cerebellar medulloblastoma cell line) - 2020/12/29 2020/12/29 rogid:cn8gYfKDpQc8J2ygnqny32sIyyU9606 rogid:16MjfkV6aoDArzVV5Qi0K2HI2lg9606 rigid:rcB/+PMkt3xctqX8BtjneHUykZI false tandem tag:n-n - - - psi-mi:"MI:0658"(multidimensional protein identification technology) psi-mi:"MI:0658"(multidimensional protein identification technology) uniprotkb:P48431 uniprotkb:Q12948 intact:EBI-6124081|uniprotkb:Q14537|ensembl:ENSP00000323588 intact:EBI-1175253|uniprotkb:Q86UP7|uniprotkb:Q9BYM1|uniprotkb:Q9NUE5|uniprotkb:Q9UDD0|uniprotkb:Q9UP06|ensembl:ENSP00000493906 psi-mi:sox2_human(display_long)|uniprotkb:SOX2(gene name)|psi-mi:SOX2(display_short) psi-mi:foxc1_human(display_long)|uniprotkb:Forkhead-related protein FKHL7(gene name synonym)|uniprotkb:Forkhead-related transcription factor 3(gene name synonym)|uniprotkb:FOXC1(gene name)|psi-mi:FOXC1(display_short)|uniprotkb:FKHL7(gene name synonym)|uniprotkb:FREAC3(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Cox et al. (2012) pubmed:23667531|imex:IM-28599 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-26574571|imex:IM-28599-3 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_003097.1|dip:DIP-59913N|ensembl:ENSG00000181449(gene)|ensembl:ENST00000325404(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001649"(osteoblast differentiation)|go:"GO:0001654"(eye development)|go:"GO:0001714"(endodermal cell fate specification)|go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006325"(chromatin organization)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0009611"(response to wounding)|go:"GO:0009653"(anatomical structure morphogenesis)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0021781"(glial cell fate commitment)|go:"GO:0021983"(pituitary gland development)|go:"GO:0021984"(adenohypophysis development)|go:"GO:0022409"(positive regulation of cell-cell adhesion)|go:"GO:0030154"(cell differentiation)|go:"GO:0030900"(forebrain development)|go:"GO:0035019"(somatic stem cell population maintenance)|go:"GO:0035198"(miRNA binding)|go:"GO:0042246"(tissue regeneration)|go:"GO:0043281"(regulation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0043410"(positive regulation of MAPK cascade)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045165"(cell fate commitment)|go:"GO:0045597"(positive regulation of cell differentiation)|go:"GO:0045665"(negative regulation of neuron differentiation)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048839"(inner ear development)|go:"GO:0050680"(negative regulation of epithelial cell proliferation)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0070848"(response to growth factor)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:0097150"(neuronal stem cell population maintenance)|interpro:IPR009071(High mobility group box, HMG)|interpro:IPR022097|interpro:IPR032643|interpro:IPR036910|mint:P48431|rcsb pdb:1O4X|rcsb pdb:2LE4|rcsb pdb:6T7B|rcsb pdb:6T90|rcsb pdb:6WX7|rcsb pdb:6WX8|rcsb pdb:6WX9|rcsb pdb:6YOV|reactome:R-HSA-2892245|reactome:R-HSA-2892247|reactome:R-HSA-3769402|reactome:R-HSA-452723|reactome:R-HSA-6785807|reactome:R-HSA-8986944 ensembl:ENST00000645831(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000792"(heterochromatin)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001525"(angiogenesis)|go:"GO:0001541"(ovarian follicle development)|go:"GO:0001654"(eye development)|go:"GO:0001657"(ureteric bud development)|go:"GO:0001701"(in utero embryonic development)|ensembl:ENSG00000054598(gene)|go:"GO:0001822"(kidney development)|go:"GO:0001945"(lymph vessel development)|go:"GO:0001958"(endochondral ossification)|go:"GO:0001974"(blood vessel remodeling)|go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0001756"(somitogenesis)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007219"(Notch signaling pathway)|go:"GO:0007507"(heart development)|go:"GO:0008134"(transcription factor binding)|go:"GO:0008283"(cell population proliferation)|go:"GO:0008354"(germ cell migration)|go:"GO:0009653"(anatomical structure morphogenesis)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010718"(positive regulation of epithelial to mesenchymal transition)|go:"GO:0014031"(mesenchymal cell development)|go:"GO:0014032"(neural crest cell development)|go:"GO:0016477"(cell migration)|go:"GO:0016525"(negative regulation of angiogenesis)|go:"GO:0021549"(cerebellum development)|go:"GO:0030154"(cell differentiation)|go:"GO:0030199"(collagen fibril organization)|go:"GO:0030203"(glycosaminoglycan metabolic process)|go:"GO:0032808"(lacrimal gland development)|go:"GO:0035050"(embryonic heart tube development)|go:"GO:0036438"(maintenance of lens transparency)|go:"GO:0038084"(vascular endothelial growth factor signaling pathway)|go:"GO:0042475"(odontogenesis of dentin-containing tooth)|go:"GO:0043010"(camera-type eye development)|go:"GO:0043388"(positive regulation of DNA binding)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045618"(positive regulation of keratinocyte differentiation)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045930"(negative regulation of mitotic cell cycle)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046620"(regulation of organ growth)|go:"GO:0048010"(vascular endothelial growth factor receptor signaling pathway)|go:"GO:0048341"(paraxial mesoderm formation)|go:"GO:0048844"(artery morphogenesis)|go:"GO:0055010"(ventricular cardiac muscle tissue morphogenesis)|go:"GO:0008301"(DNA binding, bending)|go:"GO:1990841"(promoter-specific chromatin binding)|go:"GO:1990869"(cellular response to chemokine)|go:"GO:0060038"(cardiac muscle cell proliferation)|interpro:IPR001766(Fork head transcription factor)|interpro:IPR018122|interpro:IPR030456|interpro:IPR033067|go:"GO:0070098"(chemokine-mediated signaling pathway)|interpro:IPR036388|interpro:IPR036390|mint:Q12948|go:"GO:0071364"(cellular response to epidermal growth factor stimulus)|go:"GO:0072010"(glomerular epithelium development)|go:"GO:0097746"(blood vessel diameter maintenance)|go:"GO:1901491"(negative regulation of lymphangiogenesis)|go:"GO:1901534"(positive regulation of hematopoietic progenitor cell differentiation)|go:"GO:1902038"(positive regulation of hematopoietic stem cell differentiation)|go:"GO:1902257"(negative regulation of apoptotic process involved in outflow tract morphogenesis)|go:"GO:1904798"(positive regulation of core promoter binding)|ensembl:ENSP00000493906|refseq:NP_001444.2 go:"GO:0005634"(nucleus) - - figure legend:ST2 F2B|comment:"proteins identified only in induced samples in three MudPIT analyses without BY-adjusted significance (p>0.05), but with t-test significance (p<0.05)"|dataset:Brain Disease - Neurological Diseases & Disorders|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-daoy)|taxid:9606(Homo sapiens DAOY cerebellar medulloblastoma cell line) - 2020/12/29 2020/12/29 rogid:cn8gYfKDpQc8J2ygnqny32sIyyU9606 rogid:+HuKwX8xMx86iCQW/a+vy/rWP389606 rigid:rcB/+PMkt3xctqX8BtjneHUykZI false tandem tag:n-n - - - psi-mi:"MI:0658"(multidimensional protein identification technology) psi-mi:"MI:0658"(multidimensional protein identification technology) uniprotkb:P48431 uniprotkb:O95365 intact:EBI-6124081|uniprotkb:Q14537|ensembl:ENSP00000323588 intact:EBI-2795384|uniprotkb:O00456|uniprotkb:Q14D41|uniprotkb:Q5XG86|uniprotkb:D6W619|ensembl:ENSP00000323670|ensembl:ENSP00000471865 psi-mi:sox2_human(display_long)|uniprotkb:SOX2(gene name)|psi-mi:SOX2(display_short) psi-mi:zbt7a_human(display_long)|uniprotkb:ZNF857A(gene name synonym)|uniprotkb:Zinc finger protein 857A(gene name synonym)|uniprotkb:ZBTB7A(gene name)|psi-mi:ZBTB7A(display_short)|uniprotkb:FBI1(gene name synonym)|uniprotkb:LRF(gene name synonym)|uniprotkb:ZBTB7(gene name synonym)|uniprotkb:Leukemia/lymphoma-related factor(gene name synonym)|uniprotkb:Factor that binds to inducer of short transcripts protein 1(gene name synonym)|uniprotkb:Factor binding IST protein 1(gene name synonym)|uniprotkb:HIV-1 1st-binding protein 1(gene name synonym)|uniprotkb:TTF-I-interacting peptide 21(gene name synonym)|uniprotkb:POZ and Krueppel erythroid myeloid ontogenic factor(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Cox et al. (2012) pubmed:23667531|imex:IM-28599 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-26574571|imex:IM-28599-3 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_003097.1|dip:DIP-59913N|ensembl:ENSG00000181449(gene)|ensembl:ENST00000325404(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001649"(osteoblast differentiation)|go:"GO:0001654"(eye development)|go:"GO:0001714"(endodermal cell fate specification)|go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006325"(chromatin organization)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0009611"(response to wounding)|go:"GO:0009653"(anatomical structure morphogenesis)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0021781"(glial cell fate commitment)|go:"GO:0021983"(pituitary gland development)|go:"GO:0021984"(adenohypophysis development)|go:"GO:0022409"(positive regulation of cell-cell adhesion)|go:"GO:0030154"(cell differentiation)|go:"GO:0030900"(forebrain development)|go:"GO:0035019"(somatic stem cell population maintenance)|go:"GO:0035198"(miRNA binding)|go:"GO:0042246"(tissue regeneration)|go:"GO:0043281"(regulation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0043410"(positive regulation of MAPK cascade)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045165"(cell fate commitment)|go:"GO:0045597"(positive regulation of cell differentiation)|go:"GO:0045665"(negative regulation of neuron differentiation)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048839"(inner ear development)|go:"GO:0050680"(negative regulation of epithelial cell proliferation)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0070848"(response to growth factor)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:0097150"(neuronal stem cell population maintenance)|interpro:IPR009071(High mobility group box, HMG)|interpro:IPR022097|interpro:IPR032643|interpro:IPR036910|mint:P48431|rcsb pdb:1O4X|rcsb pdb:2LE4|rcsb pdb:6T7B|rcsb pdb:6T90|rcsb pdb:6WX7|rcsb pdb:6WX8|rcsb pdb:6WX9|rcsb pdb:6YOV|reactome:R-HSA-2892245|reactome:R-HSA-2892247|reactome:R-HSA-3769402|reactome:R-HSA-452723|reactome:R-HSA-6785807|reactome:R-HSA-8986944 refseq:NP_056982.1|refseq:NP_001304919.1|refseq:XP_005259628.1|go:"GO:0097680"(double-strand break repair via classical nonhomologous end joining)|go:"GO:0140297"(DNA-binding transcription factor binding)|go:"GO:0050681"(androgen receptor binding)|go:"GO:0051090"(regulation of DNA-binding transcription factor activity)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|go:"GO:0060766"(negative regulation of androgen receptor signaling pathway)|go:"GO:2000677"(regulation of transcription regulatory region DNA binding)|interpro:IPR000210(BTB/POZ-like)|go:"GO:0070418"(DNA-dependent protein kinase complex)|interpro:IPR011333(BTB/POZ fold)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR036236|mint:O95365|rcsb pdb:2IF5|rcsb pdb:2NN2|ensembl:ENSG00000178951(gene)|ensembl:ENST00000322357(transcript)|ensembl:ENST00000601588(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000381"(regulation of alternative mRNA splicing, via spliceosome)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001222"(transcription corepressor binding)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006325"(chromatin organization)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0030183"(B cell differentiation)|go:"GO:0030512"(negative regulation of transforming growth factor beta receptor signaling pathway)|go:"GO:0034504"(protein localization to nucleus)|go:"GO:0035035"(histone acetyltransferase binding)|go:"GO:0035861"(site of double-strand break)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0043249"(erythrocyte maturation)|go:"GO:0045444"(fat cell differentiation)|go:"GO:0045746"(negative regulation of Notch signaling pathway)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0046332"(SMAD binding)|go:"GO:0046872"(metal ion binding)|go:"GO:0006110"(regulation of glycolytic process)|dip:DIP-56307N go:"GO:0005634"(nucleus) - - figure legend:ST2 F2B|comment:"proteins identified only in induced samples in three MudPIT analyses without BY-adjusted significance (p>0.05), but with t-test significance (p<0.05)"|dataset:Brain Disease - Neurological Diseases & Disorders|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-daoy)|taxid:9606(Homo sapiens DAOY cerebellar medulloblastoma cell line) - 2020/12/29 2020/12/29 rogid:cn8gYfKDpQc8J2ygnqny32sIyyU9606 rogid:2GA3qEU1lhU9iSlCbJ5ier7PYo89606 rigid:rcB/+PMkt3xctqX8BtjneHUykZI false tandem tag:n-n - - - psi-mi:"MI:0658"(multidimensional protein identification technology) psi-mi:"MI:0658"(multidimensional protein identification technology) uniprotkb:P48431 uniprotkb:Q9UIF8 intact:EBI-6124081|uniprotkb:Q14537|ensembl:ENSP00000323588 intact:EBI-741542|ensembl:ENSP00000376534|uniprotkb:Q96EA1|uniprotkb:Q96SQ8|uniprotkb:Q9P252|uniprotkb:Q9Y4N8|uniprotkb:D3DPA8 psi-mi:sox2_human(display_long)|uniprotkb:SOX2(gene name)|psi-mi:SOX2(display_short) psi-mi:baz2b_human(display_long)|uniprotkb:BAZ2B(gene name)|psi-mi:BAZ2B(display_short)|uniprotkb:KIAA1476(gene name synonym)|uniprotkb:hWALp4(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Cox et al. (2012) pubmed:23667531|imex:IM-28599 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-26574571|imex:IM-28599-3 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_003097.1|dip:DIP-59913N|ensembl:ENSG00000181449(gene)|ensembl:ENST00000325404(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001649"(osteoblast differentiation)|go:"GO:0001654"(eye development)|go:"GO:0001714"(endodermal cell fate specification)|go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006325"(chromatin organization)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0009611"(response to wounding)|go:"GO:0009653"(anatomical structure morphogenesis)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0021781"(glial cell fate commitment)|go:"GO:0021983"(pituitary gland development)|go:"GO:0021984"(adenohypophysis development)|go:"GO:0022409"(positive regulation of cell-cell adhesion)|go:"GO:0030154"(cell differentiation)|go:"GO:0030900"(forebrain development)|go:"GO:0035019"(somatic stem cell population maintenance)|go:"GO:0035198"(miRNA binding)|go:"GO:0042246"(tissue regeneration)|go:"GO:0043281"(regulation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0043410"(positive regulation of MAPK cascade)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045165"(cell fate commitment)|go:"GO:0045597"(positive regulation of cell differentiation)|go:"GO:0045665"(negative regulation of neuron differentiation)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048839"(inner ear development)|go:"GO:0050680"(negative regulation of epithelial cell proliferation)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0070848"(response to growth factor)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:0097150"(neuronal stem cell population maintenance)|interpro:IPR009071(High mobility group box, HMG)|interpro:IPR022097|interpro:IPR032643|interpro:IPR036910|mint:P48431|rcsb pdb:1O4X|rcsb pdb:2LE4|rcsb pdb:6T7B|rcsb pdb:6T90|rcsb pdb:6WX7|rcsb pdb:6WX8|rcsb pdb:6WX9|rcsb pdb:6YOV|reactome:R-HSA-2892245|reactome:R-HSA-2892247|reactome:R-HSA-3769402|reactome:R-HSA-452723|reactome:R-HSA-6785807|reactome:R-HSA-8986944 ensembl:ENSG00000123636(gene)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|go:"GO:0090647"(modulation of age-related behavioral decline)|interpro:IPR001487(Bromodomain)|interpro:IPR001739(Methyl-CpG DNA binding)|interpro:IPR001965(Zinc finger, PHD-type)|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR016177(DNA-binding, integrase-type)|interpro:IPR018359|interpro:IPR018501|interpro:IPR019787|interpro:IPR028941|interpro:IPR036427|interpro:IPR037374|mint:Q9UIF8|rcsb pdb:2E7O|rcsb pdb:3G0L|rcsb pdb:3Q2F|rcsb pdb:4CUP|rcsb pdb:4CUQ|ensembl:ENST00000392783(transcript)|rcsb pdb:4CUR|rcsb pdb:4CUS|rcsb pdb:4CUT|rcsb pdb:4CUU|rcsb pdb:4IR3|rcsb pdb:4IR4|rcsb pdb:4IR5|rcsb pdb:4IR6|rcsb pdb:4NR9|rcsb pdb:4NRA|rcsb pdb:4NRB|rcsb pdb:4NRC|rcsb pdb:4QC1|rcsb pdb:4QC3|rcsb pdb:4QF3|rcsb pdb:4RVR|rcsb pdb:4XUA|refseq:NP_038478.2|rcsb pdb:4XUB|rcsb pdb:5CQ3|rcsb pdb:5CQ4|rcsb pdb:5CQ5|rcsb pdb:5CQ6|rcsb pdb:5CQ7|rcsb pdb:5CQ8|rcsb pdb:5CQA|rcsb pdb:5CU8|rcsb pdb:5CUA|rcsb pdb:5CUB|rcsb pdb:5CUC|rcsb pdb:5CUD|rcsb pdb:5CUE|rcsb pdb:5CUG|rcsb pdb:5DYU|rcsb pdb:5DYX|rcsb pdb:5E73|rcsb pdb:5E74|rcsb pdb:5E9I|rcsb pdb:5E9K|rcsb pdb:5E9L|rcsb pdb:5E9M|rcsb pdb:5PCH|rcsb pdb:5PCI|rcsb pdb:5PCJ|rcsb pdb:5PCK|rcsb pdb:5PCL|rcsb pdb:5PCM|rcsb pdb:5PCN|rcsb pdb:5PCO|rcsb pdb:5PCP|rcsb pdb:5PCQ|rcsb pdb:5PCR|rcsb pdb:5PCS|rcsb pdb:5PCT|rcsb pdb:5PCG|rcsb pdb:5PCU|rcsb pdb:5PCV|rcsb pdb:5PCW|rcsb pdb:5PCX|rcsb pdb:5PCZ|rcsb pdb:5PD0|rcsb pdb:5PD1|rcsb pdb:5L8T|rcsb pdb:5L8U|rcsb pdb:5L96|rcsb pdb:5L97|rcsb pdb:5L98|rcsb pdb:5L99|rcsb pdb:5MGE|rcsb pdb:5MGF|rcsb pdb:5MGG|rcsb pdb:5OR9|rcsb pdb:5ORB|rcsb pdb:5PB7|rcsb pdb:5PB8|rcsb pdb:5PB9|rcsb pdb:5PBA|rcsb pdb:5PBB|rcsb pdb:5PBC|rcsb pdb:5PBD|rcsb pdb:5PBE|rcsb pdb:5PBF|rcsb pdb:5PBG|rcsb pdb:5PBH|rcsb pdb:5PBI|rcsb pdb:5PBJ|rcsb pdb:5PBK|rcsb pdb:5E9Y|rcsb pdb:5PBL|rcsb pdb:5PBM|rcsb pdb:5PBO|rcsb pdb:5PBP|rcsb pdb:5PBQ|rcsb pdb:5PBR|rcsb pdb:5PBS|rcsb pdb:5PBT|rcsb pdb:5PBU|rcsb pdb:5PBV|rcsb pdb:5PBW|rcsb pdb:5PBX|rcsb pdb:5PBY|rcsb pdb:5PBZ|rcsb pdb:5PC0|rcsb pdb:5PC1|rcsb pdb:5PC2|rcsb pdb:5PC3|rcsb pdb:5PC4|rcsb pdb:5PC5|rcsb pdb:5PC6|rcsb pdb:5PC7|rcsb pdb:5PC8|rcsb pdb:5PC9|rcsb pdb:5PCA|rcsb pdb:5PCB|rcsb pdb:5PCC|rcsb pdb:5PBN|rcsb pdb:5PCD|rcsb pdb:5PCE|rcsb pdb:5PCF|rcsb pdb:5PDY|rcsb pdb:5PDZ|rcsb pdb:5PE0|rcsb pdb:5PE1|rcsb pdb:5PE2|rcsb pdb:5PE3|rcsb pdb:5PE4|rcsb pdb:5PE5|rcsb pdb:5PE6|rcsb pdb:5PE7|rcsb pdb:5PE8|rcsb pdb:5PE9|rcsb pdb:5PEA|rcsb pdb:5PEB|rcsb pdb:5PEC|rcsb pdb:5PED|rcsb pdb:5PEE|rcsb pdb:5PEF|rcsb pdb:5PDX|rcsb pdb:5PEG|rcsb pdb:5PEH|rcsb pdb:5PEI|rcsb pdb:5PEJ|rcsb pdb:5PEK|rcsb pdb:5PEL|rcsb pdb:5PEM|rcsb pdb:5PEN|rcsb pdb:5PEO|rcsb pdb:5PD2|rcsb pdb:5PD4|rcsb pdb:5PD5|rcsb pdb:5PD6|rcsb pdb:5PD7|rcsb pdb:5PD8|rcsb pdb:5PD9|rcsb pdb:5PDA|rcsb pdb:5PDB|rcsb pdb:5PDC|rcsb pdb:5PDD|rcsb pdb:5PDE|rcsb pdb:5PDF|rcsb pdb:5PDG|rcsb pdb:5PDH|rcsb pdb:5PDI|rcsb pdb:5PDJ|rcsb pdb:5PD3|rcsb pdb:5PDK|rcsb pdb:5PDL|rcsb pdb:5PDM|rcsb pdb:5PDN|rcsb pdb:5PDO|rcsb pdb:5PDP|rcsb pdb:5PDQ|rcsb pdb:5PDR|rcsb pdb:5PDS|rcsb pdb:5PDT|rcsb pdb:5PDU|rcsb pdb:5PDV|rcsb pdb:5PDW|rcsb pdb:5PFN|rcsb pdb:5PFO|rcsb pdb:5PFP|rcsb pdb:5PFQ|rcsb pdb:5PFR|rcsb pdb:5PFS|rcsb pdb:5PFT|rcsb pdb:5PFU|rcsb pdb:5PFV|rcsb pdb:5PFW|rcsb pdb:5PFX|rcsb pdb:5PFY|rcsb pdb:5PFZ|rcsb pdb:5PG0|rcsb pdb:5PG1|rcsb pdb:5PG2|rcsb pdb:5PG3|rcsb pdb:5PG4|rcsb pdb:5PG5|rcsb pdb:5PG6|rcsb pdb:5PFM|rcsb pdb:5PG7|rcsb pdb:5PG8|rcsb pdb:5PEQ|rcsb pdb:5PES|rcsb pdb:5PET|rcsb pdb:5PEU|rcsb pdb:5PEV|rcsb pdb:5PEW|rcsb pdb:5PEX|rcsb pdb:5PEY|rcsb pdb:5PEZ|rcsb pdb:5PF0|rcsb pdb:5PF1|rcsb pdb:5PF2|rcsb pdb:5PF3|rcsb pdb:5PF4|rcsb pdb:5PF5|rcsb pdb:5PF6|rcsb pdb:5PF7|rcsb pdb:5PF8|rcsb pdb:5PF9|rcsb pdb:5PFA|rcsb pdb:5PFB|rcsb pdb:5PFC|rcsb pdb:5PFD|rcsb pdb:5PER|rcsb pdb:5PFE|rcsb pdb:5PFF|rcsb pdb:5PFG|rcsb pdb:5PFH|rcsb pdb:5PFI|rcsb pdb:5PFJ|rcsb pdb:5PFL|rcsb pdb:5PG9|rcsb pdb:5PGA|rcsb pdb:5PGB|rcsb pdb:5PGC|rcsb pdb:5PGD|rcsb pdb:5PGE|rcsb pdb:5PGF|rcsb pdb:5PGG|rcsb pdb:5PGH|rcsb pdb:5PGI|rcsb pdb:5PGJ|rcsb pdb:5PGK|rcsb pdb:5PGL|rcsb pdb:5PGN|rcsb pdb:5PGO|rcsb pdb:5PGP|rcsb pdb:5PGQ|rcsb pdb:5PGR|rcsb pdb:5PGS|rcsb pdb:5PGT|rcsb pdb:6FGT|rcsb pdb:6FGU|rcsb pdb:6FH6|rcsb pdb:6FH7|rcsb pdb:6FHQ|rcsb pdb:6FI1|ensembl:ENST00000392782|ensembl:ENSP00000376533|ensembl:ENSP00000376534|refseq:NP_001276904.1 go:"GO:0005634"(nucleus) - - figure legend:ST2 F2B|comment:"proteins identified only in induced samples in three MudPIT analyses without BY-adjusted significance (p>0.05), but with t-test significance (p<0.05)"|dataset:Brain Disease - Neurological Diseases & Disorders|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-daoy)|taxid:9606(Homo sapiens DAOY cerebellar medulloblastoma cell line) - 2020/12/29 2020/12/29 rogid:cn8gYfKDpQc8J2ygnqny32sIyyU9606 rogid:KpbxkrPxL1uFuikn8vLISOc4wog9606 rigid:rcB/+PMkt3xctqX8BtjneHUykZI false tandem tag:n-n - - - psi-mi:"MI:0658"(multidimensional protein identification technology) psi-mi:"MI:0658"(multidimensional protein identification technology) uniprotkb:P48431 uniprotkb:P36776 intact:EBI-6124081|uniprotkb:Q14537|ensembl:ENSP00000323588 intact:EBI-357448|ensembl:ENSP00000353826|intact:EBI-1054513|uniprotkb:D6W635|uniprotkb:E5KMH8|uniprotkb:P36777|uniprotkb:Q8N8K8|uniprotkb:Q9UQ95|uniprotkb:B3KPH8|uniprotkb:F5GZ27|intact:EBI-10964236 psi-mi:sox2_human(display_long)|uniprotkb:SOX2(gene name)|psi-mi:SOX2(display_short) psi-mi:lonm_human(display_long)|uniprotkb:LONHs(gene name synonym)|uniprotkb:PRSS15(gene name synonym)|uniprotkb:LONP1(gene name)|psi-mi:LONP1(display_short)|uniprotkb:Lon protease-like protein(gene name synonym)|uniprotkb:Mitochondrial ATP-dependent protease Lon(gene name synonym)|uniprotkb:Serine protease 15(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Cox et al. (2012) pubmed:23667531|imex:IM-28599 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-26574571|imex:IM-28599-3 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_003097.1|dip:DIP-59913N|ensembl:ENSG00000181449(gene)|ensembl:ENST00000325404(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001649"(osteoblast differentiation)|go:"GO:0001654"(eye development)|go:"GO:0001714"(endodermal cell fate specification)|go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006325"(chromatin organization)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0009611"(response to wounding)|go:"GO:0009653"(anatomical structure morphogenesis)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0021781"(glial cell fate commitment)|go:"GO:0021983"(pituitary gland development)|go:"GO:0021984"(adenohypophysis development)|go:"GO:0022409"(positive regulation of cell-cell adhesion)|go:"GO:0030154"(cell differentiation)|go:"GO:0030900"(forebrain development)|go:"GO:0035019"(somatic stem cell population maintenance)|go:"GO:0035198"(miRNA binding)|go:"GO:0042246"(tissue regeneration)|go:"GO:0043281"(regulation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0043410"(positive regulation of MAPK cascade)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045165"(cell fate commitment)|go:"GO:0045597"(positive regulation of cell differentiation)|go:"GO:0045665"(negative regulation of neuron differentiation)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048839"(inner ear development)|go:"GO:0050680"(negative regulation of epithelial cell proliferation)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0070848"(response to growth factor)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:0097150"(neuronal stem cell population maintenance)|interpro:IPR009071(High mobility group box, HMG)|interpro:IPR022097|interpro:IPR032643|interpro:IPR036910|mint:P48431|rcsb pdb:1O4X|rcsb pdb:2LE4|rcsb pdb:6T7B|rcsb pdb:6T90|rcsb pdb:6WX7|rcsb pdb:6WX8|rcsb pdb:6WX9|rcsb pdb:6YOV|reactome:R-HSA-2892245|reactome:R-HSA-2892247|reactome:R-HSA-3769402|reactome:R-HSA-452723|reactome:R-HSA-6785807|reactome:R-HSA-8986944 refseq:NP_001263408.1|go:"GO:0070407"(oxidation-dependent protein catabolic process)|interpro:IPR003111(Peptidase S16, lon N-terminal)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR003959(AAA ATPase, core)|go:"GO:0051603"(proteolysis involved in cellular protein catabolic process)|interpro:IPR004815(Peptidase S16, ATP-dependent protease La)|interpro:IPR008268(Peptidase S16, active site)|interpro:IPR008269(Peptidase S16, lon C-terminal)|interpro:IPR014721(Ribosomal protein S5 domain 2-type fold)|interpro:IPR015947(PUA-like)|interpro:IPR020568|interpro:IPR027065|interpro:IPR027417|interpro:IPR027503|mint:P36776|rcsb pdb:2X36|go:"GO:0051880"(G-quadruplex DNA binding)|go:"GO:0070182"(DNA polymerase binding)|rcsb pdb:6WYS|rcsb pdb:6WZV|rcsb pdb:6X1M|rcsb pdb:6X27|rcsb pdb:7KRZ|rcsb pdb:7KSL|rcsb pdb:7KSM|rcsb pdb:7NFY|rcsb pdb:7NG4|rcsb pdb:7NG5|rcsb pdb:7NGC|rcsb pdb:7NGF|rcsb pdb:7NGL|rcsb pdb:7NGP|rcsb pdb:7NGQ|ensembl:ENSG00000196365(gene)|ensembl:ENST00000360614(transcript)|go:"GO:0000002"(mitochondrial genome maintenance)|go:"GO:0001018"(mitochondrial promoter sequence-specific DNA binding)|go:"GO:0001666"(response to hypoxia)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0003727"(single-stranded RNA binding)|go:"GO:0004176"(ATP-dependent peptidase activity)|go:"GO:0004252"(serine-type endopeptidase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0005829"(cytosol)|go:"GO:0006515"(protein quality control for misfolded or incompletely synthesized proteins)|go:"GO:0007005"(mitochondrion organization)|go:"GO:0007568"(aging)|go:"GO:0009725"(response to hormone)|go:"GO:0010044"(response to aluminum ion)|go:"GO:0016020"(membrane)|go:"GO:0016887"(ATP hydrolysis activity)|go:"GO:0032042"(mitochondrial DNA metabolic process)|go:"GO:0034599"(cellular response to oxidative stress)|go:"GO:0042645"(mitochondrial nucleoid)|go:"GO:0042802"(identical protein binding)|go:"GO:0043531"(ADP binding)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0051131"(chaperone-mediated protein complex assembly)|refseq:NP_001263409.1|refseq:NP_004784.2 go:"GO:0005634"(nucleus) - - figure legend:ST2 F2B|comment:"proteins identified only in induced samples in three MudPIT analyses without BY-adjusted significance (p>0.05), but with t-test significance (p<0.05)"|dataset:Brain Disease - Neurological Diseases & Disorders|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-daoy)|taxid:9606(Homo sapiens DAOY cerebellar medulloblastoma cell line) - 2020/12/29 2020/12/29 rogid:cn8gYfKDpQc8J2ygnqny32sIyyU9606 rogid:quAPz1dZK2XdoE6WMjQJwFtx53o9606 rigid:rcB/+PMkt3xctqX8BtjneHUykZI false tandem tag:n-n - - - psi-mi:"MI:0658"(multidimensional protein identification technology) psi-mi:"MI:0658"(multidimensional protein identification technology) uniprotkb:P48431 uniprotkb:Q96T76 intact:EBI-6124081|uniprotkb:Q14537|ensembl:ENSP00000323588 intact:EBI-1044169|uniprotkb:Q9BYS9|uniprotkb:Q17RZ8|uniprotkb:Q5T455|uniprotkb:Q66K82|uniprotkb:Q7L4W8|uniprotkb:Q969Z1|uniprotkb:Q96DF1|uniprotkb:Q96MR1|uniprotkb:Q96RK5|uniprotkb:Q96SK1|uniprotkb:Q9BUE2|ensembl:ENSP00000359818|ensembl:ENSP00000412698|uniprotkb:D3DR55|uniprotkb:B0QZ75|uniprotkb:B3KPE5|uniprotkb:B4DQX2|uniprotkb:B4E2I3|uniprotkb:F8W9Y2 psi-mi:sox2_human(display_long)|uniprotkb:SOX2(gene name)|psi-mi:SOX2(display_short) psi-mi:mms19_human(display_long)|uniprotkb:MMS19(gene name)|psi-mi:MMS19(display_short)|uniprotkb:MMS19L(gene name synonym)|uniprotkb:MMS19-like protein(gene name synonym)|uniprotkb:MET18 homolog(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Cox et al. (2012) pubmed:23667531|imex:IM-28599 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-26574571|imex:IM-28599-3 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_003097.1|dip:DIP-59913N|ensembl:ENSG00000181449(gene)|ensembl:ENST00000325404(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001649"(osteoblast differentiation)|go:"GO:0001654"(eye development)|go:"GO:0001714"(endodermal cell fate specification)|go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006325"(chromatin organization)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0009611"(response to wounding)|go:"GO:0009653"(anatomical structure morphogenesis)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0021781"(glial cell fate commitment)|go:"GO:0021983"(pituitary gland development)|go:"GO:0021984"(adenohypophysis development)|go:"GO:0022409"(positive regulation of cell-cell adhesion)|go:"GO:0030154"(cell differentiation)|go:"GO:0030900"(forebrain development)|go:"GO:0035019"(somatic stem cell population maintenance)|go:"GO:0035198"(miRNA binding)|go:"GO:0042246"(tissue regeneration)|go:"GO:0043281"(regulation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0043410"(positive regulation of MAPK cascade)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045165"(cell fate commitment)|go:"GO:0045597"(positive regulation of cell differentiation)|go:"GO:0045665"(negative regulation of neuron differentiation)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048839"(inner ear development)|go:"GO:0050680"(negative regulation of epithelial cell proliferation)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0070848"(response to growth factor)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:0097150"(neuronal stem cell population maintenance)|interpro:IPR009071(High mobility group box, HMG)|interpro:IPR022097|interpro:IPR032643|interpro:IPR036910|mint:P48431|rcsb pdb:1O4X|rcsb pdb:2LE4|rcsb pdb:6T7B|rcsb pdb:6T90|rcsb pdb:6WX7|rcsb pdb:6WX8|rcsb pdb:6WX9|rcsb pdb:6YOV|reactome:R-HSA-2892245|reactome:R-HSA-2892247|reactome:R-HSA-3769402|reactome:R-HSA-452723|reactome:R-HSA-6785807|reactome:R-HSA-8986944 ensembl:ENSG00000155229(gene)|ensembl:ENST00000370782(transcript)|ensembl:ENST00000438925(transcript)|go:"GO:0000160"(phosphorelay signal transduction system)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005634"(nucleus)|go:"GO:0030331"(estrogen receptor binding)|go:"GO:0030674"(protein-macromolecule adaptor activity)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0071817"(MMXD complex)|go:"GO:0097361"(CIA complex)|go:"GO:0097428"(protein maturation by iron-sulfur cluster transfer)|go:"GO:1905168"(positive regulation of double-strand break repair via homologous recombination)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR024687|interpro:IPR029240|interpro:IPR039920|mint:Q96T76|reactome:R-HSA-2564830|go:"GO:0030159"(signaling receptor complex adaptor activity)|go:"GO:0005675"(transcription factor TFIIH holo complex)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005815"(microtubule organizing center)|go:"GO:0005819"(spindle)|go:"GO:0005829"(cytosol)|go:"GO:0006259"(DNA metabolic process)|go:"GO:0006281"(DNA repair)|go:"GO:0006289"(nucleotide-excision repair)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0007059"(chromosome segregation)|go:"GO:0009725"(response to hormone)|go:"GO:0016020"(membrane)|go:"GO:0016226"(iron-sulfur cluster assembly)|go:"GO:0019899"(enzyme binding)|refseq:NP_071757.4|refseq:NP_001276332.1|refseq:NP_001276333.1|refseq:NP_001276334.1|refseq:NP_001317057.1|refseq:XP_016872013.1 go:"GO:0005634"(nucleus) - - figure legend:ST2 F2B|comment:"proteins identified only in induced samples in three MudPIT analyses without BY-adjusted significance (p>0.05), but with t-test significance (p<0.05)"|dataset:Brain Disease - Neurological Diseases & Disorders|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-daoy)|taxid:9606(Homo sapiens DAOY cerebellar medulloblastoma cell line) - 2020/12/29 2020/12/29 rogid:cn8gYfKDpQc8J2ygnqny32sIyyU9606 rogid:sujw9MQiwau6A0dumVM7gXVMGjE9606 rigid:rcB/+PMkt3xctqX8BtjneHUykZI false tandem tag:n-n - - - psi-mi:"MI:0658"(multidimensional protein identification technology) psi-mi:"MI:0658"(multidimensional protein identification technology) uniprotkb:P48431 uniprotkb:Q9UPN9 intact:EBI-6124081|uniprotkb:Q14537|ensembl:ENSP00000323588 intact:EBI-2214398|uniprotkb:O95855|uniprotkb:Q5TG72|uniprotkb:Q5TG73|uniprotkb:Q5TG74|uniprotkb:Q9C017|uniprotkb:Q9UJ79|ensembl:ENSP00000351250 psi-mi:sox2_human(display_long)|uniprotkb:SOX2(gene name)|psi-mi:SOX2(display_short) psi-mi:tri33_human(display_long)|uniprotkb:RING-type E3 ubiquitin transferase TRIM33(gene name synonym)|uniprotkb:TRIM33(gene name)|psi-mi:TRIM33(display_short)|uniprotkb:KIAA1113(gene name synonym)|uniprotkb:RFG7(gene name synonym)|uniprotkb:TIF1G(gene name synonym)|uniprotkb:Tripartite motif-containing protein 33(gene name synonym)|uniprotkb:Transcription intermediary factor 1-gamma(gene name synonym)|uniprotkb:Ectodermin homolog(gene name synonym)|uniprotkb:RET-fused gene 7 protein(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Cox et al. (2012) pubmed:23667531|imex:IM-28599 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-26574571|imex:IM-28599-3 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_003097.1|dip:DIP-59913N|ensembl:ENSG00000181449(gene)|ensembl:ENST00000325404(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001649"(osteoblast differentiation)|go:"GO:0001654"(eye development)|go:"GO:0001714"(endodermal cell fate specification)|go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006325"(chromatin organization)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0009611"(response to wounding)|go:"GO:0009653"(anatomical structure morphogenesis)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0021781"(glial cell fate commitment)|go:"GO:0021983"(pituitary gland development)|go:"GO:0021984"(adenohypophysis development)|go:"GO:0022409"(positive regulation of cell-cell adhesion)|go:"GO:0030154"(cell differentiation)|go:"GO:0030900"(forebrain development)|go:"GO:0035019"(somatic stem cell population maintenance)|go:"GO:0035198"(miRNA binding)|go:"GO:0042246"(tissue regeneration)|go:"GO:0043281"(regulation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0043410"(positive regulation of MAPK cascade)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045165"(cell fate commitment)|go:"GO:0045597"(positive regulation of cell differentiation)|go:"GO:0045665"(negative regulation of neuron differentiation)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048839"(inner ear development)|go:"GO:0050680"(negative regulation of epithelial cell proliferation)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0070848"(response to growth factor)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:0097150"(neuronal stem cell population maintenance)|interpro:IPR009071(High mobility group box, HMG)|interpro:IPR022097|interpro:IPR032643|interpro:IPR036910|mint:P48431|rcsb pdb:1O4X|rcsb pdb:2LE4|rcsb pdb:6T7B|rcsb pdb:6T90|rcsb pdb:6WX7|rcsb pdb:6WX8|rcsb pdb:6WX9|rcsb pdb:6YOV|reactome:R-HSA-2892245|reactome:R-HSA-2892247|reactome:R-HSA-3769402|reactome:R-HSA-452723|reactome:R-HSA-6785807|reactome:R-HSA-8986944 refseq:NP_056990.3|refseq:NP_148980.2|ensembl:ENSG00000197323(gene)|ensembl:ENST00000358465(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0003677"(DNA binding)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0008270"(zinc ion binding)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0017015"(regulation of transforming growth factor beta receptor signaling pathway)|go:"GO:0030514"(negative regulation of BMP signaling pathway)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0070410"(co-SMAD binding)|go:"GO:0070412"(R-SMAD binding)|interpro:IPR000315(Zinc finger, B-box)|interpro:IPR001487(Bromodomain)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR001965(Zinc finger, PHD-type)|interpro:IPR003649(B-box, C-terminal)|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017907|interpro:IPR019786|interpro:IPR019787|interpro:IPR027370|interpro:IPR036427|mint:Q9UPN9|rcsb pdb:3U5M|rcsb pdb:3U5N|rcsb pdb:3U5O|rcsb pdb:3U5P|rcsb pdb:5MR8|reactome:R-HSA-2173795|dip:DIP-54262N go:"GO:0005634"(nucleus) - - figure legend:ST2 F2B|comment:"proteins identified only in induced samples in three MudPIT analyses without BY-adjusted significance (p>0.05), but with t-test significance (p<0.05)"|dataset:Brain Disease - Neurological Diseases & Disorders|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-daoy)|taxid:9606(Homo sapiens DAOY cerebellar medulloblastoma cell line) - 2020/12/29 2020/12/29 rogid:cn8gYfKDpQc8J2ygnqny32sIyyU9606 rogid:DB02UIWcpeneONPdG17AS08/9/A9606 rigid:rcB/+PMkt3xctqX8BtjneHUykZI false tandem tag:n-n - - - psi-mi:"MI:0658"(multidimensional protein identification technology) psi-mi:"MI:0658"(multidimensional protein identification technology) uniprotkb:P48431 uniprotkb:Q9UKA4 intact:EBI-6124081|uniprotkb:Q14537|ensembl:ENSP00000323588 intact:EBI-1049491|uniprotkb:O75124|uniprotkb:Q9NUK7|ensembl:ENSP00000025301 psi-mi:sox2_human(display_long)|uniprotkb:SOX2(gene name)|psi-mi:SOX2(display_short) psi-mi:aka11_human(display_long)|uniprotkb:Protein kinase A-anchoring protein 11(gene name synonym)|uniprotkb:A-kinase anchor protein 220 kDa(gene name synonym)|uniprotkb:AKAP11(gene name)|psi-mi:AKAP11(display_short)|uniprotkb:AKAP220(gene name synonym)|uniprotkb:KIAA0629(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Cox et al. (2012) pubmed:23667531|imex:IM-28599 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-26574571|imex:IM-28599-3 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_003097.1|dip:DIP-59913N|ensembl:ENSG00000181449(gene)|ensembl:ENST00000325404(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001649"(osteoblast differentiation)|go:"GO:0001654"(eye development)|go:"GO:0001714"(endodermal cell fate specification)|go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006325"(chromatin organization)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0009611"(response to wounding)|go:"GO:0009653"(anatomical structure morphogenesis)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0021781"(glial cell fate commitment)|go:"GO:0021983"(pituitary gland development)|go:"GO:0021984"(adenohypophysis development)|go:"GO:0022409"(positive regulation of cell-cell adhesion)|go:"GO:0030154"(cell differentiation)|go:"GO:0030900"(forebrain development)|go:"GO:0035019"(somatic stem cell population maintenance)|go:"GO:0035198"(miRNA binding)|go:"GO:0042246"(tissue regeneration)|go:"GO:0043281"(regulation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0043410"(positive regulation of MAPK cascade)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045165"(cell fate commitment)|go:"GO:0045597"(positive regulation of cell differentiation)|go:"GO:0045665"(negative regulation of neuron differentiation)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048839"(inner ear development)|go:"GO:0050680"(negative regulation of epithelial cell proliferation)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0070848"(response to growth factor)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:0097150"(neuronal stem cell population maintenance)|interpro:IPR009071(High mobility group box, HMG)|interpro:IPR022097|interpro:IPR032643|interpro:IPR036910|mint:P48431|rcsb pdb:1O4X|rcsb pdb:2LE4|rcsb pdb:6T7B|rcsb pdb:6T90|rcsb pdb:6WX7|rcsb pdb:6WX8|rcsb pdb:6WX9|rcsb pdb:6YOV|reactome:R-HSA-2892245|reactome:R-HSA-2892247|reactome:R-HSA-3769402|reactome:R-HSA-452723|reactome:R-HSA-6785807|reactome:R-HSA-8986944 refseq:XP_011533205.1|refseq:XP_011533206.1|refseq:XP_011533207.1|refseq:XP_011533208.1|refseq:NP_057332.1|refseq:XP_016875870.1|ensembl:ENSG00000023516(gene)|ensembl:ENST00000025301(transcript)|go:"GO:0003091"(renal water homeostasis)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005777"(peroxisome)|go:"GO:0005815"(microtubule organizing center)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0008104"(protein localization)|go:"GO:0008157"(protein phosphatase 1 binding)|go:"GO:0019207"(kinase regulator activity)|go:"GO:0030866"(cortical actin cytoskeleton organization)|go:"GO:0034237"(protein kinase A regulatory subunit binding)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0036010"(protein localization to endosome)|go:"GO:0051018"(protein kinase A binding)|interpro:IPR008382(A-kinase anchor 110 kDa)|mint:Q9UKA4 go:"GO:0005634"(nucleus) - - figure legend:ST2 F2B|comment:"proteins identified only in induced samples in three MudPIT analyses without BY-adjusted significance (p>0.05), but with t-test significance (p<0.05)"|dataset:Brain Disease - Neurological Diseases & Disorders|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-daoy)|taxid:9606(Homo sapiens DAOY cerebellar medulloblastoma cell line) - 2020/12/29 2020/12/29 rogid:cn8gYfKDpQc8J2ygnqny32sIyyU9606 rogid:EoQOZuPirXCY2k5migb2Fr6utZ09606 rigid:rcB/+PMkt3xctqX8BtjneHUykZI false tandem tag:n-n - - - psi-mi:"MI:0658"(multidimensional protein identification technology) psi-mi:"MI:0658"(multidimensional protein identification technology) uniprotkb:P48431 uniprotkb:O15027 intact:EBI-6124081|uniprotkb:Q14537|ensembl:ENSP00000323588 intact:EBI-357515|intact:EBI-1384174|uniprotkb:A1YCA4|uniprotkb:Q5SXP0|uniprotkb:Q5SXP1|uniprotkb:Q8N347|uniprotkb:Q96HP1|uniprotkb:J3KNL6|uniprotkb:Q4G0D7|intact:EBI-28968206|ensembl:ENSP00000325827|intact:EBI-10967582|intact:EBI-21024388 psi-mi:sox2_human(display_long)|uniprotkb:SOX2(gene name)|psi-mi:SOX2(display_short) psi-mi:sc16a_human(display_long)|uniprotkb:KIAA0310(gene name synonym)|uniprotkb:SEC16(gene name synonym)|uniprotkb:SEC16L(gene name synonym)|uniprotkb:SEC16 homolog A(gene name synonym)|uniprotkb:SEC16A(gene name)|psi-mi:SEC16A(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Cox et al. (2012) pubmed:23667531|imex:IM-28599 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-26574571|imex:IM-28599-3 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_003097.1|dip:DIP-59913N|ensembl:ENSG00000181449(gene)|ensembl:ENST00000325404(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001649"(osteoblast differentiation)|go:"GO:0001654"(eye development)|go:"GO:0001714"(endodermal cell fate specification)|go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006325"(chromatin organization)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0009611"(response to wounding)|go:"GO:0009653"(anatomical structure morphogenesis)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0021781"(glial cell fate commitment)|go:"GO:0021983"(pituitary gland development)|go:"GO:0021984"(adenohypophysis development)|go:"GO:0022409"(positive regulation of cell-cell adhesion)|go:"GO:0030154"(cell differentiation)|go:"GO:0030900"(forebrain development)|go:"GO:0035019"(somatic stem cell population maintenance)|go:"GO:0035198"(miRNA binding)|go:"GO:0042246"(tissue regeneration)|go:"GO:0043281"(regulation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0043410"(positive regulation of MAPK cascade)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045165"(cell fate commitment)|go:"GO:0045597"(positive regulation of cell differentiation)|go:"GO:0045665"(negative regulation of neuron differentiation)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048839"(inner ear development)|go:"GO:0050680"(negative regulation of epithelial cell proliferation)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0070848"(response to growth factor)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:0097150"(neuronal stem cell population maintenance)|interpro:IPR009071(High mobility group box, HMG)|interpro:IPR022097|interpro:IPR032643|interpro:IPR036910|mint:P48431|rcsb pdb:1O4X|rcsb pdb:2LE4|rcsb pdb:6T7B|rcsb pdb:6T90|rcsb pdb:6WX7|rcsb pdb:6WX8|rcsb pdb:6WX9|rcsb pdb:6YOV|reactome:R-HSA-2892245|reactome:R-HSA-2892247|reactome:R-HSA-3769402|reactome:R-HSA-452723|reactome:R-HSA-6785807|reactome:R-HSA-8986944 refseq:XP_011517562.1|refseq:XP_005266191.1|refseq:XP_011517548.1|refseq:XP_011517549.1|refseq:XP_011517550.1|refseq:XP_011517557.1|refseq:XP_011517559.1|refseq:XP_011517561.1|go:"GO:0070973"(protein localization to endoplasmic reticulum exit site)|go:"GO:0072659"(protein localization to plasma membrane)|interpro:IPR024298|interpro:IPR024340|interpro:IPR024880|mint:O15027|reactome:R-HSA-204005|ensembl:ENSG00000148396(gene)|ensembl:ENST00000313050(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0006914"(autophagy)|go:"GO:0007029"(endoplasmic reticulum organization)|go:"GO:0007030"(Golgi organization)|go:"GO:0012507"(ER to Golgi transport vesicle membrane)|go:"GO:0021762"(substantia nigra development)|go:"GO:0031090"(organelle membrane)|go:"GO:0032527"(protein exit from endoplasmic reticulum)|go:"GO:0034976"(response to endoplasmic reticulum stress)|go:"GO:0043000"(Golgi to plasma membrane CFTR protein transport)|go:"GO:0048208"(COPII vesicle coating)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0050821"(protein stabilization)|go:"GO:0070863"(positive regulation of protein exit from endoplasmic reticulum)|go:"GO:0070971"(endoplasmic reticulum exit site)|ensembl:ENSP00000325827|refseq:NP_055681.1|refseq:XP_011517554.1|refseq:NP_001263347.1|dip:DIP-27588N go:"GO:0005634"(nucleus) - - figure legend:ST2 F2B|comment:"proteins identified only in induced samples in three MudPIT analyses without BY-adjusted significance (p>0.05), but with t-test significance (p<0.05)"|dataset:Brain Disease - Neurological Diseases & Disorders|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-daoy)|taxid:9606(Homo sapiens DAOY cerebellar medulloblastoma cell line) - 2020/12/29 2020/12/29 rogid:cn8gYfKDpQc8J2ygnqny32sIyyU9606 rogid:yB65QJbL+WBjtWO5UXAx2DCRbwI9606 rigid:rcB/+PMkt3xctqX8BtjneHUykZI false tandem tag:n-n - - - psi-mi:"MI:0658"(multidimensional protein identification technology) psi-mi:"MI:0658"(multidimensional protein identification technology) uniprotkb:P48431 uniprotkb:Q8IU81 intact:EBI-6124081|uniprotkb:Q14537|ensembl:ENSP00000323588 intact:EBI-6115514|uniprotkb:Q53EL7|uniprotkb:Q6DC95|uniprotkb:Q9BRZ9|uniprotkb:Q9Y4P4|ensembl:ENSP00000307265 psi-mi:sox2_human(display_long)|uniprotkb:SOX2(gene name)|psi-mi:SOX2(display_short) psi-mi:i2bp1_human(display_long)|uniprotkb:IRF2BP1(gene name)|psi-mi:IRF2BP1(display_short)|uniprotkb:Probable E3 ubiquitin-protein ligase IRF2BP1(gene name synonym)|uniprotkb:Probable RING-type E3 ubiquitin transferase IRF2BP1(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Cox et al. (2012) pubmed:23667531|imex:IM-28599 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-26574571|imex:IM-28599-3 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_003097.1|dip:DIP-59913N|ensembl:ENSG00000181449(gene)|ensembl:ENST00000325404(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001649"(osteoblast differentiation)|go:"GO:0001654"(eye development)|go:"GO:0001714"(endodermal cell fate specification)|go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006325"(chromatin organization)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0009611"(response to wounding)|go:"GO:0009653"(anatomical structure morphogenesis)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0021781"(glial cell fate commitment)|go:"GO:0021983"(pituitary gland development)|go:"GO:0021984"(adenohypophysis development)|go:"GO:0022409"(positive regulation of cell-cell adhesion)|go:"GO:0030154"(cell differentiation)|go:"GO:0030900"(forebrain development)|go:"GO:0035019"(somatic stem cell population maintenance)|go:"GO:0035198"(miRNA binding)|go:"GO:0042246"(tissue regeneration)|go:"GO:0043281"(regulation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0043410"(positive regulation of MAPK cascade)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045165"(cell fate commitment)|go:"GO:0045597"(positive regulation of cell differentiation)|go:"GO:0045665"(negative regulation of neuron differentiation)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048839"(inner ear development)|go:"GO:0050680"(negative regulation of epithelial cell proliferation)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0070848"(response to growth factor)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:0097150"(neuronal stem cell population maintenance)|interpro:IPR009071(High mobility group box, HMG)|interpro:IPR022097|interpro:IPR032643|interpro:IPR036910|mint:P48431|rcsb pdb:1O4X|rcsb pdb:2LE4|rcsb pdb:6T7B|rcsb pdb:6T90|rcsb pdb:6WX7|rcsb pdb:6WX8|rcsb pdb:6WX9|rcsb pdb:6YOV|reactome:R-HSA-2892245|reactome:R-HSA-2892247|reactome:R-HSA-3769402|reactome:R-HSA-452723|reactome:R-HSA-6785807|reactome:R-HSA-8986944 refseq:NP_056464.1|ensembl:ENSG00000170604(gene)|ensembl:ENST00000302165(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|go:"GO:0061630"(ubiquitin protein ligase activity)|interpro:IPR018957|interpro:IPR022750|interpro:IPR044882|mint:Q8IU81 go:"GO:0005634"(nucleus) - - figure legend:ST2 F2B|comment:"proteins identified only in induced samples in three MudPIT analyses without BY-adjusted significance (p>0.05), but with t-test significance (p<0.05)"|dataset:Brain Disease - Neurological Diseases & Disorders|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-daoy)|taxid:9606(Homo sapiens DAOY cerebellar medulloblastoma cell line) - 2020/12/29 2020/12/29 rogid:cn8gYfKDpQc8J2ygnqny32sIyyU9606 rogid:0ooWsKsxvLQtWbTA3FsVfO+6TBA9606 rigid:rcB/+PMkt3xctqX8BtjneHUykZI false tandem tag:n-n - - - psi-mi:"MI:0658"(multidimensional protein identification technology) psi-mi:"MI:0658"(multidimensional protein identification technology) uniprotkb:P48431 uniprotkb:Q5T4S7 intact:EBI-6124081|uniprotkb:Q14537|ensembl:ENSP00000323588 intact:EBI-1995940|intact:EBI-1059327|uniprotkb:A8MPT2|uniprotkb:A8MQ33|uniprotkb:A8MQB1|uniprotkb:O60646|uniprotkb:O75050|uniprotkb:Q4QRK5|uniprotkb:Q5T4S8|uniprotkb:Q5T4S9|uniprotkb:Q5TBN8|uniprotkb:Q5TBP2|uniprotkb:Q6DKH8|uniprotkb:Q6P4A4|uniprotkb:Q7L8P7|uniprotkb:Q8IXJ4|uniprotkb:Q8TDN5|uniprotkb:Q8WV67|uniprotkb:Q9HA46|uniprotkb:Q9P2N9|uniprotkb:Q9UG82|ensembl:ENSP00000364403 psi-mi:sox2_human(display_long)|uniprotkb:SOX2(gene name)|psi-mi:SOX2(display_short) psi-mi:ubr4_human(display_long)|uniprotkb:UBR4(gene name)|psi-mi:UBR4(display_short)|uniprotkb:KIAA0462(gene name synonym)|uniprotkb:KIAA1307(gene name synonym)|uniprotkb:RBAF600(gene name synonym)|uniprotkb:ZUBR1(gene name synonym)|uniprotkb:N-recognin-4(gene name synonym)|uniprotkb:Zinc finger UBR1-type protein 1(gene name synonym)|uniprotkb:Retinoblastoma-associated factor of 600 kDa(gene name synonym)|uniprotkb:600 kDa retinoblastoma protein-associated factor(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase UBR4(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Cox et al. (2012) pubmed:23667531|imex:IM-28599 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-26574571|imex:IM-28599-3 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_003097.1|dip:DIP-59913N|ensembl:ENSG00000181449(gene)|ensembl:ENST00000325404(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001649"(osteoblast differentiation)|go:"GO:0001654"(eye development)|go:"GO:0001714"(endodermal cell fate specification)|go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006325"(chromatin organization)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0009611"(response to wounding)|go:"GO:0009653"(anatomical structure morphogenesis)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0021781"(glial cell fate commitment)|go:"GO:0021983"(pituitary gland development)|go:"GO:0021984"(adenohypophysis development)|go:"GO:0022409"(positive regulation of cell-cell adhesion)|go:"GO:0030154"(cell differentiation)|go:"GO:0030900"(forebrain development)|go:"GO:0035019"(somatic stem cell population maintenance)|go:"GO:0035198"(miRNA binding)|go:"GO:0042246"(tissue regeneration)|go:"GO:0043281"(regulation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0043410"(positive regulation of MAPK cascade)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045165"(cell fate commitment)|go:"GO:0045597"(positive regulation of cell differentiation)|go:"GO:0045665"(negative regulation of neuron differentiation)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048839"(inner ear development)|go:"GO:0050680"(negative regulation of epithelial cell proliferation)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0070848"(response to growth factor)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:0097150"(neuronal stem cell population maintenance)|interpro:IPR009071(High mobility group box, HMG)|interpro:IPR022097|interpro:IPR032643|interpro:IPR036910|mint:P48431|rcsb pdb:1O4X|rcsb pdb:2LE4|rcsb pdb:6T7B|rcsb pdb:6T90|rcsb pdb:6WX7|rcsb pdb:6WX8|rcsb pdb:6WX9|rcsb pdb:6YOV|reactome:R-HSA-2892245|reactome:R-HSA-2892247|reactome:R-HSA-3769402|reactome:R-HSA-452723|reactome:R-HSA-6785807|reactome:R-HSA-8986944 refseq:NP_065816.2|ensembl:ENST00000375218|ensembl:ENSP00000364403|ensembl:ENSP00000364366|ensembl:ENSG00000127481(gene)|ensembl:ENST00000375254(transcript)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0008270"(zinc ion binding)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0035579"(specific granule membrane)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0070821"(tertiary granule membrane)|go:"GO:0101003"(ficolin-1-rich granule membrane)|interpro:IPR003126(Zinc finger, N-recognin)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR025704|interpro:IPR036322|mint:Q5T4S7|reactome:R-HSA-6798695|reactome:R-HSA-983168 go:"GO:0005634"(nucleus) - - figure legend:ST2 F2B|comment:"proteins identified only in induced samples in three MudPIT analyses without BY-adjusted significance (p>0.05), but with t-test significance (p<0.05)"|dataset:Brain Disease - Neurological Diseases & Disorders|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-daoy)|taxid:9606(Homo sapiens DAOY cerebellar medulloblastoma cell line) - 2020/12/29 2020/12/29 rogid:cn8gYfKDpQc8J2ygnqny32sIyyU9606 rogid:8Iown8oj965YAir+95+3om5+1YM9606 rigid:rcB/+PMkt3xctqX8BtjneHUykZI false tandem tag:n-n - - - psi-mi:"MI:0658"(multidimensional protein identification technology) psi-mi:"MI:0658"(multidimensional protein identification technology) uniprotkb:P48431 uniprotkb:Q99856 intact:EBI-6124081|uniprotkb:Q14537|ensembl:ENSP00000323588 intact:EBI-5458244|uniprotkb:Q5I858|uniprotkb:Q6P9C6|uniprotkb:Q8IZA7|uniprotkb:Q8N4Z3|ensembl:ENSP00000263620 psi-mi:sox2_human(display_long)|uniprotkb:SOX2(gene name)|psi-mi:SOX2(display_short) psi-mi:ari3a_human(display_long)|uniprotkb:ARID3A(gene name)|psi-mi:ARID3A(display_short)|uniprotkb:DRIL1(gene name synonym)|uniprotkb:DRIL3(gene name synonym)|uniprotkb:DRX(gene name synonym)|uniprotkb:E2FBP1(gene name synonym)|uniprotkb:B-cell regulator of IgH transcription(gene name synonym)|uniprotkb:Dead ringer-like protein 1(gene name synonym)|uniprotkb:E2F-binding protein 1(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Cox et al. (2012) pubmed:23667531|imex:IM-28599 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-26574571|imex:IM-28599-3 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_003097.1|dip:DIP-59913N|ensembl:ENSG00000181449(gene)|ensembl:ENST00000325404(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001649"(osteoblast differentiation)|go:"GO:0001654"(eye development)|go:"GO:0001714"(endodermal cell fate specification)|go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006325"(chromatin organization)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0009611"(response to wounding)|go:"GO:0009653"(anatomical structure morphogenesis)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0021781"(glial cell fate commitment)|go:"GO:0021983"(pituitary gland development)|go:"GO:0021984"(adenohypophysis development)|go:"GO:0022409"(positive regulation of cell-cell adhesion)|go:"GO:0030154"(cell differentiation)|go:"GO:0030900"(forebrain development)|go:"GO:0035019"(somatic stem cell population maintenance)|go:"GO:0035198"(miRNA binding)|go:"GO:0042246"(tissue regeneration)|go:"GO:0043281"(regulation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0043410"(positive regulation of MAPK cascade)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045165"(cell fate commitment)|go:"GO:0045597"(positive regulation of cell differentiation)|go:"GO:0045665"(negative regulation of neuron differentiation)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048839"(inner ear development)|go:"GO:0050680"(negative regulation of epithelial cell proliferation)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0070848"(response to growth factor)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:0097150"(neuronal stem cell population maintenance)|interpro:IPR009071(High mobility group box, HMG)|interpro:IPR022097|interpro:IPR032643|interpro:IPR036910|mint:P48431|rcsb pdb:1O4X|rcsb pdb:2LE4|rcsb pdb:6T7B|rcsb pdb:6T90|rcsb pdb:6WX7|rcsb pdb:6WX8|rcsb pdb:6WX9|rcsb pdb:6YOV|reactome:R-HSA-2892245|reactome:R-HSA-2892247|reactome:R-HSA-3769402|reactome:R-HSA-452723|reactome:R-HSA-6785807|reactome:R-HSA-8986944 refseq:NP_005215.1|refseq:XP_005259570.1|refseq:XP_005259571.1|refseq:XP_016881934.1|ensembl:ENSG00000116017(gene)|ensembl:ENST00000263620(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0042802"(identical protein binding)|go:"GO:0045121"(membrane raft)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|interpro:IPR001606(AT-rich interaction region)|interpro:IPR023334|interpro:IPR036431|mint:Q99856|rcsb pdb:2KK0|rcsb pdb:4LJX|reactome:R-HSA-6804116 go:"GO:0005634"(nucleus) - - figure legend:ST2 F2B|comment:"proteins identified only in induced samples in three MudPIT analyses without BY-adjusted significance (p>0.05), but with t-test significance (p<0.05)"|dataset:Brain Disease - Neurological Diseases & Disorders|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-daoy)|taxid:9606(Homo sapiens DAOY cerebellar medulloblastoma cell line) - 2020/12/29 2020/12/29 rogid:cn8gYfKDpQc8J2ygnqny32sIyyU9606 rogid:OovnBk28KzvFoKdJICElQQRBKH49606 rigid:rcB/+PMkt3xctqX8BtjneHUykZI false tandem tag:n-n - - - psi-mi:"MI:0658"(multidimensional protein identification technology) psi-mi:"MI:0658"(multidimensional protein identification technology) uniprotkb:P48431 uniprotkb:Q93008 intact:EBI-6124081|uniprotkb:Q14537|ensembl:ENSP00000323588 intact:EBI-302524|intact:EBI-1058656|intact:EBI-28978998|ensembl:ENSP00000367558|uniprotkb:O75550|uniprotkb:Q8WWT3|uniprotkb:Q8WX12 psi-mi:sox2_human(display_long)|uniprotkb:SOX2(gene name)|psi-mi:SOX2(display_short) psi-mi:usp9x_human(display_long)|uniprotkb:USP9X(gene name)|psi-mi:USP9X(display_short)|uniprotkb:DFFRX(gene name synonym)|uniprotkb:USP9(gene name synonym)|uniprotkb:Ubiquitin-specific-processing protease FAF-X(gene name synonym)|uniprotkb:Deubiquitinating enzyme FAF-X(gene name synonym)|uniprotkb:Fat facets protein-related, X-linked(gene name synonym)|uniprotkb:Ubiquitin-specific protease 9, X chromosome(gene name synonym)|uniprotkb:FAM(gene name synonym)|uniprotkb:Fat facets in mammals(gene name synonym)|uniprotkb:Ubiquitin thioesterase FAF-X(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Cox et al. (2012) pubmed:23667531|imex:IM-28599 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-26574571|imex:IM-28599-3 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_003097.1|dip:DIP-59913N|ensembl:ENSG00000181449(gene)|ensembl:ENST00000325404(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001649"(osteoblast differentiation)|go:"GO:0001654"(eye development)|go:"GO:0001714"(endodermal cell fate specification)|go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006325"(chromatin organization)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0009611"(response to wounding)|go:"GO:0009653"(anatomical structure morphogenesis)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0021781"(glial cell fate commitment)|go:"GO:0021983"(pituitary gland development)|go:"GO:0021984"(adenohypophysis development)|go:"GO:0022409"(positive regulation of cell-cell adhesion)|go:"GO:0030154"(cell differentiation)|go:"GO:0030900"(forebrain development)|go:"GO:0035019"(somatic stem cell population maintenance)|go:"GO:0035198"(miRNA binding)|go:"GO:0042246"(tissue regeneration)|go:"GO:0043281"(regulation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0043410"(positive regulation of MAPK cascade)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045165"(cell fate commitment)|go:"GO:0045597"(positive regulation of cell differentiation)|go:"GO:0045665"(negative regulation of neuron differentiation)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048839"(inner ear development)|go:"GO:0050680"(negative regulation of epithelial cell proliferation)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0070848"(response to growth factor)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:0097150"(neuronal stem cell population maintenance)|interpro:IPR009071(High mobility group box, HMG)|interpro:IPR022097|interpro:IPR032643|interpro:IPR036910|mint:P48431|rcsb pdb:1O4X|rcsb pdb:2LE4|rcsb pdb:6T7B|rcsb pdb:6T90|rcsb pdb:6WX7|rcsb pdb:6WX8|rcsb pdb:6WX9|rcsb pdb:6YOV|reactome:R-HSA-2892245|reactome:R-HSA-2892247|reactome:R-HSA-3769402|reactome:R-HSA-452723|reactome:R-HSA-6785807|reactome:R-HSA-8986944 ensembl:ENSG00000124486(gene)|ensembl:ENST00000378308(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0001764"(neuron migration)|go:"GO:0004197"(cysteine-type endopeptidase activity)|go:"GO:0004843"(thiol-dependent deubiquitinase)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0007049"(cell cycle)|go:"GO:0007059"(chromosome segregation)|go:"GO:0007179"(transforming growth factor beta receptor signaling pathway)|go:"GO:0007292"(female gamete generation)|go:"GO:0008104"(protein localization)|go:"GO:0008234"(cysteine-type peptidase activity)|go:"GO:0016020"(membrane)|go:"GO:0016477"(cell migration)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0016579"(protein deubiquitination)|go:"GO:0030426"(growth cone)|go:"GO:0030509"(BMP signaling pathway)|go:"GO:0042752"(regulation of circadian rhythm)|go:"GO:0048511"(rhythmic process)|reactome:R-HSA-2173795|reactome:R-HSA-5689880|reactome:R-HSA-8866652|reactome:R-HSA-9013420|reactome:R-HSA-9013424|reactome:R-HSA-9033241|reactome:R-HSA-977225|go:"GO:0048675"(axon extension)|refseq:NP_001034679.2|refseq:NP_001034680.2|go:"GO:0050821"(protein stabilization)|go:"GO:0051301"(cell division)|go:"GO:0070410"(co-SMAD binding)|go:"GO:0071947"(protein deubiquitination involved in ubiquitin-dependent protein catabolic process)|go:"GO:0101005"(deubiquitinase activity)|go:"GO:1901537"(positive regulation of DNA demethylation)|go:"GO:1990000"(amyloid fibril formation)|go:"GO:1990380"(Lys48-specific deubiquitinase activity)|interpro:IPR001394(Peptidase C19, ubiquitin carboxyl-terminal hydrolase 2)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR018200|interpro:IPR021905|interpro:IPR028889|interpro:IPR031226|interpro:IPR038765|mint:Q93008|rcsb pdb:5VBD|rcsb pdb:5WCH|ensembl:ENST00000324545|ensembl:ENSP00000316357|ensembl:ENSP00000367558|dip:DIP-27562N go:"GO:0005634"(nucleus) - - figure legend:ST2 F2B|comment:"proteins identified only in induced samples in three MudPIT analyses without BY-adjusted significance (p>0.05), but with t-test significance (p<0.05)"|dataset:Brain Disease - Neurological Diseases & Disorders|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-daoy)|taxid:9606(Homo sapiens DAOY cerebellar medulloblastoma cell line) - 2020/12/29 2020/12/29 rogid:cn8gYfKDpQc8J2ygnqny32sIyyU9606 rogid:f9AWz8rAV8rMTqcQ46VrYYLTHq89606 rigid:rcB/+PMkt3xctqX8BtjneHUykZI false tandem tag:n-n - - - psi-mi:"MI:0658"(multidimensional protein identification technology) psi-mi:"MI:0658"(multidimensional protein identification technology) uniprotkb:P48431 uniprotkb:Q9H6E5 intact:EBI-6124081|uniprotkb:Q14537|ensembl:ENSP00000323588 intact:EBI-2511680|ensembl:ENSP00000419607|uniprotkb:Q9H6H7|uniprotkb:Q7L583|uniprotkb:Q2NL65|uniprotkb:A1A527|intact:EBI-2809257|uniprotkb:A8K995 psi-mi:sox2_human(display_long)|uniprotkb:SOX2(gene name)|psi-mi:SOX2(display_short) psi-mi:stpap_human(display_long)|uniprotkb:TUT1(gene name)|psi-mi:TUT1(display_short)|uniprotkb:RBM21(gene name synonym)|uniprotkb:RNA-binding motif protein 21(gene name synonym)|uniprotkb:U6 snRNA-specific terminal uridylyltransferase 1(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Cox et al. (2012) pubmed:23667531|imex:IM-28599 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-26574571|imex:IM-28599-3 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_003097.1|dip:DIP-59913N|ensembl:ENSG00000181449(gene)|ensembl:ENST00000325404(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001649"(osteoblast differentiation)|go:"GO:0001654"(eye development)|go:"GO:0001714"(endodermal cell fate specification)|go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006325"(chromatin organization)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0009611"(response to wounding)|go:"GO:0009653"(anatomical structure morphogenesis)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0021781"(glial cell fate commitment)|go:"GO:0021983"(pituitary gland development)|go:"GO:0021984"(adenohypophysis development)|go:"GO:0022409"(positive regulation of cell-cell adhesion)|go:"GO:0030154"(cell differentiation)|go:"GO:0030900"(forebrain development)|go:"GO:0035019"(somatic stem cell population maintenance)|go:"GO:0035198"(miRNA binding)|go:"GO:0042246"(tissue regeneration)|go:"GO:0043281"(regulation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0043410"(positive regulation of MAPK cascade)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045165"(cell fate commitment)|go:"GO:0045597"(positive regulation of cell differentiation)|go:"GO:0045665"(negative regulation of neuron differentiation)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048839"(inner ear development)|go:"GO:0050680"(negative regulation of epithelial cell proliferation)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0070848"(response to growth factor)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:0097150"(neuronal stem cell population maintenance)|interpro:IPR009071(High mobility group box, HMG)|interpro:IPR022097|interpro:IPR032643|interpro:IPR036910|mint:P48431|rcsb pdb:1O4X|rcsb pdb:2LE4|rcsb pdb:6T7B|rcsb pdb:6T90|rcsb pdb:6WX7|rcsb pdb:6WX8|rcsb pdb:6WX9|rcsb pdb:6YOV|reactome:R-HSA-2892245|reactome:R-HSA-2892247|reactome:R-HSA-3769402|reactome:R-HSA-452723|reactome:R-HSA-6785807|reactome:R-HSA-8986944 rcsb pdb:5WU6|rcsb pdb:5WU5|ensembl:ENSG00000149016(gene)|ensembl:ENST00000476907(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0003730"(mRNA 3'-UTR binding)|go:"GO:0004652"(polynucleotide adenylyltransferase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006378"(mRNA polyadenylation)|go:"GO:0016180"(snRNA processing)|go:"GO:0016607"(nuclear speck)|go:"GO:0016779"(nucleotidyltransferase activity)|go:"GO:0017070"(U6 snRNA binding)|go:"GO:0019899"(enzyme binding)|go:"GO:0031123"(RNA 3'-end processing)|go:"GO:0034477"(U6 snRNA 3'-end processing)|go:"GO:0046872"(metal ion binding)|go:"GO:0050265"(RNA uridylyltransferase activity)|go:"GO:0098789"(pre-mRNA cleavage required for polyadenylation)|go:"GO:1990817"(RNA adenylyltransferase activity)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR002058(PAP/25A-associated)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR034388|interpro:IPR035979|interpro:IPR036236|interpro:IPR043519|mint:Q9H6E5|rcsb pdb:2E5G|rcsb pdb:5WU1|rcsb pdb:5WU2|rcsb pdb:5WU3|rcsb pdb:5WU4|go:"GO:0005730"(nucleolus)|refseq:NP_073741.2|dip:DIP-53651N go:"GO:0005634"(nucleus) - - figure legend:ST2 F2B|comment:"proteins identified only in induced samples in three MudPIT analyses without BY-adjusted significance (p>0.05), but with t-test significance (p<0.05)"|dataset:Brain Disease - Neurological Diseases & Disorders|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-daoy)|taxid:9606(Homo sapiens DAOY cerebellar medulloblastoma cell line) - 2020/12/29 2020/12/29 rogid:cn8gYfKDpQc8J2ygnqny32sIyyU9606 rogid:7Df5H4dyiKBTRo4xiRZGbzGvzbk9606 rigid:rcB/+PMkt3xctqX8BtjneHUykZI false tandem tag:n-n - - - psi-mi:"MI:0658"(multidimensional protein identification technology) psi-mi:"MI:0658"(multidimensional protein identification technology) uniprotkb:P48431 uniprotkb:Q70CQ2 intact:EBI-6124081|uniprotkb:Q14537|ensembl:ENSP00000323588 intact:EBI-6256020|uniprotkb:A8MWD0|uniprotkb:B3KWU9|uniprotkb:O60316|uniprotkb:O94834|uniprotkb:Q3B777|uniprotkb:Q6P6C9|uniprotkb:Q7L8P6|uniprotkb:Q8N3T9|uniprotkb:Q8TBW2|uniprotkb:Q9UGA1|ensembl:ENSP00000381577 psi-mi:sox2_human(display_long)|uniprotkb:SOX2(gene name)|psi-mi:SOX2(display_short) psi-mi:ubp34_human(display_long)|uniprotkb:USP34(gene name)|psi-mi:USP34(display_short)|uniprotkb:KIAA0570(gene name synonym)|uniprotkb:KIAA0729(gene name synonym)|uniprotkb:Deubiquitinating enzyme 34(gene name synonym)|uniprotkb:Ubiquitin thioesterase 34(gene name synonym)|uniprotkb:Ubiquitin-specific-processing protease 34(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Cox et al. (2012) pubmed:23667531|imex:IM-28599 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-26574571|imex:IM-28599-3 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_003097.1|dip:DIP-59913N|ensembl:ENSG00000181449(gene)|ensembl:ENST00000325404(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001649"(osteoblast differentiation)|go:"GO:0001654"(eye development)|go:"GO:0001714"(endodermal cell fate specification)|go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006325"(chromatin organization)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0009611"(response to wounding)|go:"GO:0009653"(anatomical structure morphogenesis)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0021781"(glial cell fate commitment)|go:"GO:0021983"(pituitary gland development)|go:"GO:0021984"(adenohypophysis development)|go:"GO:0022409"(positive regulation of cell-cell adhesion)|go:"GO:0030154"(cell differentiation)|go:"GO:0030900"(forebrain development)|go:"GO:0035019"(somatic stem cell population maintenance)|go:"GO:0035198"(miRNA binding)|go:"GO:0042246"(tissue regeneration)|go:"GO:0043281"(regulation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0043410"(positive regulation of MAPK cascade)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045165"(cell fate commitment)|go:"GO:0045597"(positive regulation of cell differentiation)|go:"GO:0045665"(negative regulation of neuron differentiation)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048839"(inner ear development)|go:"GO:0050680"(negative regulation of epithelial cell proliferation)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0070848"(response to growth factor)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:0097150"(neuronal stem cell population maintenance)|interpro:IPR009071(High mobility group box, HMG)|interpro:IPR022097|interpro:IPR032643|interpro:IPR036910|mint:P48431|rcsb pdb:1O4X|rcsb pdb:2LE4|rcsb pdb:6T7B|rcsb pdb:6T90|rcsb pdb:6WX7|rcsb pdb:6WX8|rcsb pdb:6WX9|rcsb pdb:6YOV|reactome:R-HSA-2892245|reactome:R-HSA-2892247|reactome:R-HSA-3769402|reactome:R-HSA-452723|reactome:R-HSA-6785807|reactome:R-HSA-8986944 refseq:NP_055524.3|ensembl:ENSG00000115464(gene)|ensembl:ENST00000398571(transcript)|go:"GO:0004197"(cysteine-type endopeptidase activity)|go:"GO:0004843"(thiol-dependent deubiquitinase)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0016579"(protein deubiquitination)|go:"GO:0071108"(protein K48-linked deubiquitination)|go:"GO:0090263"(positive regulation of canonical Wnt signaling pathway)|interpro:IPR001394(Peptidase C19, ubiquitin carboxyl-terminal hydrolase 2)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR018200|interpro:IPR021905|interpro:IPR028889|interpro:IPR038765|mint:Q70CQ2|reactome:R-HSA-201681|reactome:R-HSA-5689880 go:"GO:0005634"(nucleus) - - figure legend:ST2 F2B|comment:"proteins identified only in induced samples in three MudPIT analyses without BY-adjusted significance (p>0.05), but with t-test significance (p<0.05)"|dataset:Brain Disease - Neurological Diseases & Disorders|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-daoy)|taxid:9606(Homo sapiens DAOY cerebellar medulloblastoma cell line) - 2020/12/29 2020/12/29 rogid:cn8gYfKDpQc8J2ygnqny32sIyyU9606 rogid:ouPBRH6ndkATju67iwZYOl1wYWM9606 rigid:rcB/+PMkt3xctqX8BtjneHUykZI false tandem tag:n-n - - - psi-mi:"MI:0658"(multidimensional protein identification technology) psi-mi:"MI:0658"(multidimensional protein identification technology) uniprotkb:P48431 uniprotkb:Q8IWT3 intact:EBI-6124081|uniprotkb:Q14537|ensembl:ENSP00000323588 intact:EBI-311123|uniprotkb:O75188|uniprotkb:Q68CP2|uniprotkb:Q68D92|uniprotkb:Q8N3W9|uniprotkb:Q9BU56|intact:EBI-2845754|uniprotkb:Q5TCY3|ensembl:ENSP00000252050 psi-mi:sox2_human(display_long)|uniprotkb:SOX2(gene name)|psi-mi:SOX2(display_short) psi-mi:cul9_human(display_long)|uniprotkb:CUL9(gene name)|psi-mi:CUL9(display_short)|uniprotkb:H7AP1(gene name synonym)|uniprotkb:KIAA0708(gene name synonym)|uniprotkb:UbcH7-associated protein 1(gene name synonym)|uniprotkb:PARC(gene name synonym)|uniprotkb:p53-associated parkin-like cytoplasmic protein(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Cox et al. (2012) pubmed:23667531|imex:IM-28599 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-26574571|imex:IM-28599-3 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_003097.1|dip:DIP-59913N|ensembl:ENSG00000181449(gene)|ensembl:ENST00000325404(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001649"(osteoblast differentiation)|go:"GO:0001654"(eye development)|go:"GO:0001714"(endodermal cell fate specification)|go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006325"(chromatin organization)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0009611"(response to wounding)|go:"GO:0009653"(anatomical structure morphogenesis)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0021781"(glial cell fate commitment)|go:"GO:0021983"(pituitary gland development)|go:"GO:0021984"(adenohypophysis development)|go:"GO:0022409"(positive regulation of cell-cell adhesion)|go:"GO:0030154"(cell differentiation)|go:"GO:0030900"(forebrain development)|go:"GO:0035019"(somatic stem cell population maintenance)|go:"GO:0035198"(miRNA binding)|go:"GO:0042246"(tissue regeneration)|go:"GO:0043281"(regulation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0043410"(positive regulation of MAPK cascade)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045165"(cell fate commitment)|go:"GO:0045597"(positive regulation of cell differentiation)|go:"GO:0045665"(negative regulation of neuron differentiation)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048839"(inner ear development)|go:"GO:0050680"(negative regulation of epithelial cell proliferation)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0070848"(response to growth factor)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:0097150"(neuronal stem cell population maintenance)|interpro:IPR009071(High mobility group box, HMG)|interpro:IPR022097|interpro:IPR032643|interpro:IPR036910|mint:P48431|rcsb pdb:1O4X|rcsb pdb:2LE4|rcsb pdb:6T7B|rcsb pdb:6T90|rcsb pdb:6WX7|rcsb pdb:6WX8|rcsb pdb:6WX9|rcsb pdb:6YOV|reactome:R-HSA-2892245|reactome:R-HSA-2892247|reactome:R-HSA-3769402|reactome:R-HSA-452723|reactome:R-HSA-6785807|reactome:R-HSA-8986944 refseq:NP_055904.1|ensembl:ENSG00000112659(gene)|ensembl:ENST00000252050(transcript)|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0005524"(ATP binding)|go:"GO:0005829"(cytosol)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0007088"(regulation of mitotic nuclear division)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0016740"(transferase activity)|go:"GO:0031461"(cullin-RING ubiquitin ligase complex)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0046872"(metal ion binding)|interpro:IPR001373(Cullin, N-terminal region)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR002867(Zinc finger, C6HC-type)|interpro:IPR004939(Anaphase-promoting complex, subunit 10)|interpro:IPR008979(Galactose-binding like)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR014722(Translation protein SH3-like, subgroup)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR016157(Cullin, conserved site)|interpro:IPR016158(Cullin homology)|interpro:IPR017907|interpro:IPR019559|interpro:IPR021097|interpro:IPR031222|interpro:IPR036317|interpro:IPR036388|interpro:IPR044066|mint:Q8IWT3|rcsb pdb:2JUF|reactome:R-HSA-8951664 go:"GO:0005634"(nucleus) - - figure legend:ST2 F2B|comment:"proteins identified only in induced samples in three MudPIT analyses without BY-adjusted significance (p>0.05), but with t-test significance (p<0.05)"|dataset:Brain Disease - Neurological Diseases & Disorders|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-daoy)|taxid:9606(Homo sapiens DAOY cerebellar medulloblastoma cell line) - 2020/12/29 2020/12/29 rogid:cn8gYfKDpQc8J2ygnqny32sIyyU9606 rogid:l3eOdyfEVm0PkkDykJXN270o1Kc9606 rigid:rcB/+PMkt3xctqX8BtjneHUykZI false tandem tag:n-n - - - psi-mi:"MI:0658"(multidimensional protein identification technology) psi-mi:"MI:0658"(multidimensional protein identification technology) uniprotkb:P48431 uniprotkb:Q9NTK5 intact:EBI-6124081|uniprotkb:Q14537|ensembl:ENSP00000323588 intact:EBI-766468|uniprotkb:Q5BJD7|uniprotkb:Q8NCI8|uniprotkb:Q96CU1|uniprotkb:Q96SV2|uniprotkb:Q9P1D3|uniprotkb:Q9UNY9|uniprotkb:Q9Y6G4|uniprotkb:D7EHM2|ensembl:ENSP00000284719 psi-mi:sox2_human(display_long)|uniprotkb:SOX2(gene name)|psi-mi:SOX2(display_short) psi-mi:ola1_human(display_long)|uniprotkb:GTPBP9(gene name synonym)|uniprotkb:GTP-binding protein 9(gene name synonym)|uniprotkb:OLA1(gene name)|psi-mi:OLA1(display_short)|uniprotkb:PTD004(orf name)|uniprotkb:PRO2455(orf name)|uniprotkb:DNA damage-regulated overexpressed in cancer 45(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Cox et al. (2012) pubmed:23667531|imex:IM-28599 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-26574571|imex:IM-28599-3 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_003097.1|dip:DIP-59913N|ensembl:ENSG00000181449(gene)|ensembl:ENST00000325404(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001649"(osteoblast differentiation)|go:"GO:0001654"(eye development)|go:"GO:0001714"(endodermal cell fate specification)|go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006325"(chromatin organization)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0009611"(response to wounding)|go:"GO:0009653"(anatomical structure morphogenesis)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0021781"(glial cell fate commitment)|go:"GO:0021983"(pituitary gland development)|go:"GO:0021984"(adenohypophysis development)|go:"GO:0022409"(positive regulation of cell-cell adhesion)|go:"GO:0030154"(cell differentiation)|go:"GO:0030900"(forebrain development)|go:"GO:0035019"(somatic stem cell population maintenance)|go:"GO:0035198"(miRNA binding)|go:"GO:0042246"(tissue regeneration)|go:"GO:0043281"(regulation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0043410"(positive regulation of MAPK cascade)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045165"(cell fate commitment)|go:"GO:0045597"(positive regulation of cell differentiation)|go:"GO:0045665"(negative regulation of neuron differentiation)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048839"(inner ear development)|go:"GO:0050680"(negative regulation of epithelial cell proliferation)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0070848"(response to growth factor)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:0097150"(neuronal stem cell population maintenance)|interpro:IPR009071(High mobility group box, HMG)|interpro:IPR022097|interpro:IPR032643|interpro:IPR036910|mint:P48431|rcsb pdb:1O4X|rcsb pdb:2LE4|rcsb pdb:6T7B|rcsb pdb:6T90|rcsb pdb:6WX7|rcsb pdb:6WX8|rcsb pdb:6WX9|rcsb pdb:6YOV|reactome:R-HSA-2892245|reactome:R-HSA-2892247|reactome:R-HSA-3769402|reactome:R-HSA-452723|reactome:R-HSA-6785807|reactome:R-HSA-8986944 refseq:NP_001011708.1|refseq:NP_037473.3|dip:DIP-34591N|ensembl:ENST00000284719(transcript)|go:"GO:0005524"(ATP binding)|go:"GO:0005525"(GTP binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0016020"(membrane)|go:"GO:0016787"(hydrolase activity)|go:"GO:0016887"(ATP hydrolysis activity)|go:"GO:0031093"(platelet alpha granule lumen)|go:"GO:0043022"(ribosome binding)|go:"GO:0043023"(ribosomal large subunit binding)|go:"GO:0045296"(cadherin binding)|go:"GO:0046034"(ATP metabolic process)|go:"GO:0046872"(metal ion binding)|go:"GO:0070062"(extracellular exosome)|interpro:IPR004095(TGS)|interpro:IPR004396(Conserved hypothetical protein CHP00092)|interpro:IPR006073(GTP1/OBG)|interpro:IPR012675(Beta-grasp fold, ferredoxin-type)|interpro:IPR012676(TGS-like)|interpro:IPR013029(Protein of unknown function DUF933)|interpro:IPR023192|interpro:IPR027417|interpro:IPR031167|interpro:IPR041706|mint:Q9NTK5|rcsb pdb:2OHF|reactome:R-HSA-114608|ensembl:ENSG00000138430(gene) go:"GO:0005634"(nucleus) - - figure legend:ST2 F2B|comment:"proteins identified only in induced samples in three MudPIT analyses without BY-adjusted significance (p>0.05), but with t-test significance (p<0.05)"|dataset:Brain Disease - Neurological Diseases & Disorders|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-daoy)|taxid:9606(Homo sapiens DAOY cerebellar medulloblastoma cell line) - 2020/12/29 2020/12/29 rogid:cn8gYfKDpQc8J2ygnqny32sIyyU9606 rogid:aQk5XBcKpx1YSW4mHtyRsTpimvk9606 rigid:rcB/+PMkt3xctqX8BtjneHUykZI false tandem tag:n-n - - - psi-mi:"MI:0658"(multidimensional protein identification technology) psi-mi:"MI:0658"(multidimensional protein identification technology) uniprotkb:P48431 uniprotkb:Q08170 intact:EBI-6124081|uniprotkb:Q14537|ensembl:ENSP00000323588 intact:EBI-722621|uniprotkb:Q5VXP1|uniprotkb:Q9BUA4|ensembl:ENSP00000362900|uniprotkb:Q9UEB5 psi-mi:sox2_human(display_long)|uniprotkb:SOX2(gene name)|psi-mi:SOX2(display_short) psi-mi:srsf4_human(display_long)|uniprotkb:Pre-mRNA-splicing factor SRP75(gene name synonym)|uniprotkb:SRP001LB(gene name synonym)|uniprotkb:SFRS4(gene name synonym)|uniprotkb:Splicing factor, arginine/serine-rich 4(gene name synonym)|uniprotkb:SRSF4(gene name)|psi-mi:SRSF4(display_short)|uniprotkb:SRP75(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Cox et al. (2012) pubmed:23667531|imex:IM-28599 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-26574571|imex:IM-28599-3 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_003097.1|dip:DIP-59913N|ensembl:ENSG00000181449(gene)|ensembl:ENST00000325404(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001649"(osteoblast differentiation)|go:"GO:0001654"(eye development)|go:"GO:0001714"(endodermal cell fate specification)|go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006325"(chromatin organization)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0009611"(response to wounding)|go:"GO:0009653"(anatomical structure morphogenesis)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0021781"(glial cell fate commitment)|go:"GO:0021983"(pituitary gland development)|go:"GO:0021984"(adenohypophysis development)|go:"GO:0022409"(positive regulation of cell-cell adhesion)|go:"GO:0030154"(cell differentiation)|go:"GO:0030900"(forebrain development)|go:"GO:0035019"(somatic stem cell population maintenance)|go:"GO:0035198"(miRNA binding)|go:"GO:0042246"(tissue regeneration)|go:"GO:0043281"(regulation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0043410"(positive regulation of MAPK cascade)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045165"(cell fate commitment)|go:"GO:0045597"(positive regulation of cell differentiation)|go:"GO:0045665"(negative regulation of neuron differentiation)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048839"(inner ear development)|go:"GO:0050680"(negative regulation of epithelial cell proliferation)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0070848"(response to growth factor)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:0097150"(neuronal stem cell population maintenance)|interpro:IPR009071(High mobility group box, HMG)|interpro:IPR022097|interpro:IPR032643|interpro:IPR036910|mint:P48431|rcsb pdb:1O4X|rcsb pdb:2LE4|rcsb pdb:6T7B|rcsb pdb:6T90|rcsb pdb:6WX7|rcsb pdb:6WX8|rcsb pdb:6WX9|rcsb pdb:6YOV|reactome:R-HSA-2892245|reactome:R-HSA-2892247|reactome:R-HSA-3769402|reactome:R-HSA-452723|reactome:R-HSA-6785807|reactome:R-HSA-8986944 refseq:NP_005617.2|ensembl:ENSG00000116350(gene)|ensembl:ENST00000373795(transcript)|go:"GO:0000375"(RNA splicing, via transesterification reactions)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006397"(mRNA processing)|go:"GO:0008380"(RNA splicing)|go:"GO:0016607"(nuclear speck)|go:"GO:0032868"(response to insulin)|go:"GO:0048025"(negative regulation of mRNA splicing, via spliceosome)|go:"GO:1990825"(sequence-specific mRNA binding)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR035585|interpro:IPR035979|mint:Q08170|reactome:R-HSA-159236|reactome:R-HSA-72163|reactome:R-HSA-72187|reactome:R-HSA-73856 go:"GO:0005634"(nucleus) - - figure legend:ST2 F2B|comment:"proteins identified only in induced samples in three MudPIT analyses without BY-adjusted significance (p>0.05), but with t-test significance (p<0.05)"|dataset:Brain Disease - Neurological Diseases & Disorders|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-daoy)|taxid:9606(Homo sapiens DAOY cerebellar medulloblastoma cell line) - 2020/12/29 2020/12/29 rogid:cn8gYfKDpQc8J2ygnqny32sIyyU9606 rogid:LVIhOlsJ8rUYB68fWFDsovUGTeU9606 rigid:rcB/+PMkt3xctqX8BtjneHUykZI false tandem tag:n-n - - - psi-mi:"MI:0658"(multidimensional protein identification technology) psi-mi:"MI:0658"(multidimensional protein identification technology) uniprotkb:P48431 uniprotkb:Q15773 intact:EBI-6124081|uniprotkb:Q14537|ensembl:ENSP00000323588 intact:EBI-1051875|intact:EBI-9357094|ensembl:ENSP00000203630|ensembl:ENSP00000403941|ensembl:ENSP00000446317 psi-mi:sox2_human(display_long)|uniprotkb:SOX2(gene name)|psi-mi:SOX2(display_short) psi-mi:mlf2_human(display_long)|uniprotkb:Myelodysplasia-myeloid leukemia factor 2(gene name synonym)|uniprotkb:MLF2(gene name)|psi-mi:MLF2(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Cox et al. (2012) pubmed:23667531|imex:IM-28599 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-26574571|imex:IM-28599-3 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_003097.1|dip:DIP-59913N|ensembl:ENSG00000181449(gene)|ensembl:ENST00000325404(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001649"(osteoblast differentiation)|go:"GO:0001654"(eye development)|go:"GO:0001714"(endodermal cell fate specification)|go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006325"(chromatin organization)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0009611"(response to wounding)|go:"GO:0009653"(anatomical structure morphogenesis)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0021781"(glial cell fate commitment)|go:"GO:0021983"(pituitary gland development)|go:"GO:0021984"(adenohypophysis development)|go:"GO:0022409"(positive regulation of cell-cell adhesion)|go:"GO:0030154"(cell differentiation)|go:"GO:0030900"(forebrain development)|go:"GO:0035019"(somatic stem cell population maintenance)|go:"GO:0035198"(miRNA binding)|go:"GO:0042246"(tissue regeneration)|go:"GO:0043281"(regulation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0043410"(positive regulation of MAPK cascade)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045165"(cell fate commitment)|go:"GO:0045597"(positive regulation of cell differentiation)|go:"GO:0045665"(negative regulation of neuron differentiation)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048839"(inner ear development)|go:"GO:0050680"(negative regulation of epithelial cell proliferation)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0070848"(response to growth factor)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:0097150"(neuronal stem cell population maintenance)|interpro:IPR009071(High mobility group box, HMG)|interpro:IPR022097|interpro:IPR032643|interpro:IPR036910|mint:P48431|rcsb pdb:1O4X|rcsb pdb:2LE4|rcsb pdb:6T7B|rcsb pdb:6T90|rcsb pdb:6WX7|rcsb pdb:6WX8|rcsb pdb:6WX9|rcsb pdb:6YOV|reactome:R-HSA-2892245|reactome:R-HSA-2892247|reactome:R-HSA-3769402|reactome:R-HSA-452723|reactome:R-HSA-6785807|reactome:R-HSA-8986944 refseq:NP_005430.1|ensembl:ENSG00000089693(gene)|ensembl:ENST00000203630(transcript)|ensembl:ENST00000435120(transcript)|ensembl:ENST00000539187(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0016020"(membrane)|interpro:IPR019376|mint:Q15773 go:"GO:0005634"(nucleus) - - figure legend:ST2 F2B|comment:"proteins identified only in induced samples in three MudPIT analyses without BY-adjusted significance (p>0.05), but with t-test significance (p<0.05)"|dataset:Brain Disease - Neurological Diseases & Disorders|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-daoy)|taxid:9606(Homo sapiens DAOY cerebellar medulloblastoma cell line) - 2020/12/29 2020/12/29 rogid:cn8gYfKDpQc8J2ygnqny32sIyyU9606 rogid:Ix7bMALTVwBVty3IAuUn+PP/0BU9606 rigid:rcB/+PMkt3xctqX8BtjneHUykZI false tandem tag:n-n - - - psi-mi:"MI:0658"(multidimensional protein identification technology) psi-mi:"MI:0658"(multidimensional protein identification technology) uniprotkb:P48431 uniprotkb:Q8NEM2 intact:EBI-6124081|uniprotkb:Q14537|ensembl:ENSP00000323588 intact:EBI-744700|uniprotkb:Q96N60|uniprotkb:Q9BVS0|uniprotkb:Q9H6P6|ensembl:ENSP00000306473 psi-mi:sox2_human(display_long)|uniprotkb:SOX2(gene name)|psi-mi:SOX2(display_short) psi-mi:shcbp_human(display_long)|uniprotkb:SHCBP1(gene name)|psi-mi:SHCBP1(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Cox et al. (2012) pubmed:23667531|imex:IM-28599 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-26574571|imex:IM-28599-3 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_003097.1|dip:DIP-59913N|ensembl:ENSG00000181449(gene)|ensembl:ENST00000325404(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001649"(osteoblast differentiation)|go:"GO:0001654"(eye development)|go:"GO:0001714"(endodermal cell fate specification)|go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006325"(chromatin organization)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0009611"(response to wounding)|go:"GO:0009653"(anatomical structure morphogenesis)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0021781"(glial cell fate commitment)|go:"GO:0021983"(pituitary gland development)|go:"GO:0021984"(adenohypophysis development)|go:"GO:0022409"(positive regulation of cell-cell adhesion)|go:"GO:0030154"(cell differentiation)|go:"GO:0030900"(forebrain development)|go:"GO:0035019"(somatic stem cell population maintenance)|go:"GO:0035198"(miRNA binding)|go:"GO:0042246"(tissue regeneration)|go:"GO:0043281"(regulation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0043410"(positive regulation of MAPK cascade)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045165"(cell fate commitment)|go:"GO:0045597"(positive regulation of cell differentiation)|go:"GO:0045665"(negative regulation of neuron differentiation)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048839"(inner ear development)|go:"GO:0050680"(negative regulation of epithelial cell proliferation)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0070848"(response to growth factor)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:0097150"(neuronal stem cell population maintenance)|interpro:IPR009071(High mobility group box, HMG)|interpro:IPR022097|interpro:IPR032643|interpro:IPR036910|mint:P48431|rcsb pdb:1O4X|rcsb pdb:2LE4|rcsb pdb:6T7B|rcsb pdb:6T90|rcsb pdb:6WX7|rcsb pdb:6WX8|rcsb pdb:6WX9|rcsb pdb:6YOV|reactome:R-HSA-2892245|reactome:R-HSA-2892247|reactome:R-HSA-3769402|reactome:R-HSA-452723|reactome:R-HSA-6785807|reactome:R-HSA-8986944 refseq:NP_079021.3|ensembl:ENSG00000171241(gene)|ensembl:ENST00000303383(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0005819"(spindle)|go:"GO:0008543"(fibroblast growth factor receptor signaling pathway)|go:"GO:0030496"(midbody)|go:"GO:2000177"(regulation of neural precursor cell proliferation)|interpro:IPR006626(Parallel beta-helix repeat)|interpro:IPR011050(Pectin lyase fold/virulence factor)|interpro:IPR012334(Pectin lyase fold)|interpro:IPR039448|mint:Q8NEM2 go:"GO:0005634"(nucleus) - - figure legend:ST2 F2B|comment:"proteins identified only in induced samples in three MudPIT analyses without BY-adjusted significance (p>0.05), but with t-test significance (p<0.05)"|dataset:Brain Disease - Neurological Diseases & Disorders|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-daoy)|taxid:9606(Homo sapiens DAOY cerebellar medulloblastoma cell line) - 2020/12/29 2020/12/29 rogid:cn8gYfKDpQc8J2ygnqny32sIyyU9606 rogid:VkqhT9kcant5+JwTeubTotVcLfo9606 rigid:rcB/+PMkt3xctqX8BtjneHUykZI false tandem tag:n-n - - - psi-mi:"MI:0658"(multidimensional protein identification technology) psi-mi:"MI:0658"(multidimensional protein identification technology) uniprotkb:P48431 uniprotkb:Q96G75 intact:EBI-6124081|uniprotkb:Q14537|ensembl:ENSP00000323588 intact:EBI-745055|uniprotkb:Q6UVY7|uniprotkb:Q9H6F6|uniprotkb:Q1HE27|ensembl:ENSP00000320623|ensembl:ENSP00000420875 psi-mi:sox2_human(display_long)|uniprotkb:SOX2(gene name)|psi-mi:SOX2(display_short) psi-mi:rmd5b_human(display_long)|uniprotkb:RMND5B(gene name)|psi-mi:RMND5B(display_short)|uniprotkb:Protein RMD5 homolog B(gene name synonym)|uniprotkb:UNQ2508/PRO5996(orf name) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Cox et al. (2012) pubmed:23667531|imex:IM-28599 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-26574571|imex:IM-28599-3 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_003097.1|dip:DIP-59913N|ensembl:ENSG00000181449(gene)|ensembl:ENST00000325404(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001649"(osteoblast differentiation)|go:"GO:0001654"(eye development)|go:"GO:0001714"(endodermal cell fate specification)|go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006325"(chromatin organization)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0009611"(response to wounding)|go:"GO:0009653"(anatomical structure morphogenesis)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0021781"(glial cell fate commitment)|go:"GO:0021983"(pituitary gland development)|go:"GO:0021984"(adenohypophysis development)|go:"GO:0022409"(positive regulation of cell-cell adhesion)|go:"GO:0030154"(cell differentiation)|go:"GO:0030900"(forebrain development)|go:"GO:0035019"(somatic stem cell population maintenance)|go:"GO:0035198"(miRNA binding)|go:"GO:0042246"(tissue regeneration)|go:"GO:0043281"(regulation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0043410"(positive regulation of MAPK cascade)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045165"(cell fate commitment)|go:"GO:0045597"(positive regulation of cell differentiation)|go:"GO:0045665"(negative regulation of neuron differentiation)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048839"(inner ear development)|go:"GO:0050680"(negative regulation of epithelial cell proliferation)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0070848"(response to growth factor)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:0097150"(neuronal stem cell population maintenance)|interpro:IPR009071(High mobility group box, HMG)|interpro:IPR022097|interpro:IPR032643|interpro:IPR036910|mint:P48431|rcsb pdb:1O4X|rcsb pdb:2LE4|rcsb pdb:6T7B|rcsb pdb:6T90|rcsb pdb:6WX7|rcsb pdb:6WX8|rcsb pdb:6WX9|rcsb pdb:6YOV|reactome:R-HSA-2892245|reactome:R-HSA-2892247|reactome:R-HSA-3769402|reactome:R-HSA-452723|reactome:R-HSA-6785807|reactome:R-HSA-8986944 refseq:NP_073599.2|refseq:NP_001275723.1|refseq:NP_001275724.1|ensembl:ENSG00000145916(gene)|ensembl:ENST00000313386(transcript)|ensembl:ENST00000515098(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0034657"(GID complex)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0046872"(metal ion binding)|go:"GO:0061630"(ubiquitin protein ligase activity)|interpro:IPR006594(LisH dimerisation motif)|interpro:IPR006595(CTLH, C-terminal to LisH motif)|interpro:IPR013144(CT11-RanBPM)|interpro:IPR037681|interpro:IPR044063|mint:Q96G75|interpro:IPR024964|refseq:XP_005266026.1|refseq:XP_005266028.1|refseq:XP_005266029.1|refseq:XP_016865216.1|refseq:XP_016865217.1 go:"GO:0005634"(nucleus) - - figure legend:ST2 F2B|comment:"proteins identified only in induced samples in three MudPIT analyses without BY-adjusted significance (p>0.05), but with t-test significance (p<0.05)"|dataset:Brain Disease - Neurological Diseases & Disorders|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-daoy)|taxid:9606(Homo sapiens DAOY cerebellar medulloblastoma cell line) - 2020/12/29 2020/12/29 rogid:cn8gYfKDpQc8J2ygnqny32sIyyU9606 rogid:Nh7+IbLuA5+PC4Z2E2Nk5j6Kvvw9606 rigid:rcB/+PMkt3xctqX8BtjneHUykZI false tandem tag:n-n - - - psi-mi:"MI:0658"(multidimensional protein identification technology) psi-mi:"MI:0658"(multidimensional protein identification technology) uniprotkb:P48431 uniprotkb:Q8WVC0 intact:EBI-6124081|uniprotkb:Q14537|ensembl:ENSP00000323588 intact:EBI-932432|uniprotkb:Q96N99|ensembl:ENSP00000299601 psi-mi:sox2_human(display_long)|uniprotkb:SOX2(gene name)|psi-mi:SOX2(display_short) psi-mi:leo1_human(display_long)|uniprotkb:LEO1(gene name)|psi-mi:LEO1(display_short)|uniprotkb:RDL(gene name synonym)|uniprotkb:Replicative senescence down-regulated leo1-like protein(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Cox et al. (2012) pubmed:23667531|imex:IM-28599 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-26574571|imex:IM-28599-3 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_003097.1|dip:DIP-59913N|ensembl:ENSG00000181449(gene)|ensembl:ENST00000325404(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001649"(osteoblast differentiation)|go:"GO:0001654"(eye development)|go:"GO:0001714"(endodermal cell fate specification)|go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006325"(chromatin organization)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0009611"(response to wounding)|go:"GO:0009653"(anatomical structure morphogenesis)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0021781"(glial cell fate commitment)|go:"GO:0021983"(pituitary gland development)|go:"GO:0021984"(adenohypophysis development)|go:"GO:0022409"(positive regulation of cell-cell adhesion)|go:"GO:0030154"(cell differentiation)|go:"GO:0030900"(forebrain development)|go:"GO:0035019"(somatic stem cell population maintenance)|go:"GO:0035198"(miRNA binding)|go:"GO:0042246"(tissue regeneration)|go:"GO:0043281"(regulation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0043410"(positive regulation of MAPK cascade)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045165"(cell fate commitment)|go:"GO:0045597"(positive regulation of cell differentiation)|go:"GO:0045665"(negative regulation of neuron differentiation)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048839"(inner ear development)|go:"GO:0050680"(negative regulation of epithelial cell proliferation)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0070848"(response to growth factor)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:0097150"(neuronal stem cell population maintenance)|interpro:IPR009071(High mobility group box, HMG)|interpro:IPR022097|interpro:IPR032643|interpro:IPR036910|mint:P48431|rcsb pdb:1O4X|rcsb pdb:2LE4|rcsb pdb:6T7B|rcsb pdb:6T90|rcsb pdb:6WX7|rcsb pdb:6WX8|rcsb pdb:6WX9|rcsb pdb:6YOV|reactome:R-HSA-2892245|reactome:R-HSA-2892247|reactome:R-HSA-3769402|reactome:R-HSA-452723|reactome:R-HSA-6785807|reactome:R-HSA-8986944 refseq:NP_001273359.1|refseq:NP_620147.1|dip:DIP-37885N|ensembl:ENSG00000166477(gene)|ensembl:ENST00000299601(transcript)|go:"GO:0001650"(fibrillar center)|go:"GO:0001711"(endodermal cell fate commitment)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0006368"(transcription elongation from RNA polymerase II promoter)|go:"GO:0006378"(mRNA polyadenylation)|go:"GO:0010390"(histone monoubiquitination)|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0016593"(Cdc73/Paf1 complex)|go:"GO:0019827"(stem cell population maintenance)|go:"GO:0031442"(positive regulation of mRNA 3'-end processing)|go:"GO:0032968"(positive regulation of transcription elongation from RNA polymerase II promoter)|go:"GO:0033523"(histone H2B ubiquitination)|go:"GO:0045638"(negative regulation of myeloid cell differentiation)|go:"GO:1990269"(RNA polymerase II C-terminal domain phosphoserine binding)|interpro:IPR007149(Leo1-like protein)|mint:Q8WVC0|rcsb pdb:4M6T|rcsb pdb:6GMH|rcsb pdb:6TED|reactome:R-HSA-112382|reactome:R-HSA-201722|reactome:R-HSA-674695|reactome:R-HSA-75955|reactome:R-HSA-8866654 go:"GO:0005634"(nucleus) - - figure legend:ST2 F2B|comment:"proteins identified only in induced samples in three MudPIT analyses without BY-adjusted significance (p>0.05), but with t-test significance (p<0.05)"|dataset:Brain Disease - Neurological Diseases & Disorders|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-daoy)|taxid:9606(Homo sapiens DAOY cerebellar medulloblastoma cell line) - 2020/12/29 2020/12/29 rogid:cn8gYfKDpQc8J2ygnqny32sIyyU9606 rogid:o0aaW4nxzWuPZ8/pMZpa9Qz9oEA9606 rigid:rcB/+PMkt3xctqX8BtjneHUykZI false tandem tag:n-n - - - psi-mi:"MI:0658"(multidimensional protein identification technology) psi-mi:"MI:0658"(multidimensional protein identification technology) uniprotkb:P48431 uniprotkb:Q9P0J7 intact:EBI-6124081|uniprotkb:Q14537|ensembl:ENSP00000323588 intact:EBI-6870925|ensembl:ENSP00000386738|uniprotkb:Q9UFE8|uniprotkb:Q9H8P5|uniprotkb:Q4ZG04|uniprotkb:Q9BWK2|uniprotkb:Q53SC7 psi-mi:sox2_human(display_long)|uniprotkb:SOX2(gene name)|psi-mi:SOX2(display_short) psi-mi:kcmf1_human(display_long)|uniprotkb:FGF-induced in gastric cancer(gene name synonym)|uniprotkb:FIGC(gene name synonym)|uniprotkb:Potassium channel modulatory factor(gene name synonym)|uniprotkb:ZZ-type zinc finger-containing protein 1(gene name synonym)|uniprotkb:ZZZ1(gene name synonym)|uniprotkb:KCMF1(gene name)|psi-mi:KCMF1(display_short)|uniprotkb:RING-type E3 ubiquitin transferase KCMF1(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Cox et al. (2012) pubmed:23667531|imex:IM-28599 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-26574571|imex:IM-28599-3 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_003097.1|dip:DIP-59913N|ensembl:ENSG00000181449(gene)|ensembl:ENST00000325404(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001649"(osteoblast differentiation)|go:"GO:0001654"(eye development)|go:"GO:0001714"(endodermal cell fate specification)|go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006325"(chromatin organization)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0009611"(response to wounding)|go:"GO:0009653"(anatomical structure morphogenesis)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0021781"(glial cell fate commitment)|go:"GO:0021983"(pituitary gland development)|go:"GO:0021984"(adenohypophysis development)|go:"GO:0022409"(positive regulation of cell-cell adhesion)|go:"GO:0030154"(cell differentiation)|go:"GO:0030900"(forebrain development)|go:"GO:0035019"(somatic stem cell population maintenance)|go:"GO:0035198"(miRNA binding)|go:"GO:0042246"(tissue regeneration)|go:"GO:0043281"(regulation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0043410"(positive regulation of MAPK cascade)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045165"(cell fate commitment)|go:"GO:0045597"(positive regulation of cell differentiation)|go:"GO:0045665"(negative regulation of neuron differentiation)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048839"(inner ear development)|go:"GO:0050680"(negative regulation of epithelial cell proliferation)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0070848"(response to growth factor)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:0097150"(neuronal stem cell population maintenance)|interpro:IPR009071(High mobility group box, HMG)|interpro:IPR022097|interpro:IPR032643|interpro:IPR036910|mint:P48431|rcsb pdb:1O4X|rcsb pdb:2LE4|rcsb pdb:6T7B|rcsb pdb:6T90|rcsb pdb:6WX7|rcsb pdb:6WX8|rcsb pdb:6WX9|rcsb pdb:6YOV|reactome:R-HSA-2892245|reactome:R-HSA-2892247|reactome:R-HSA-3769402|reactome:R-HSA-452723|reactome:R-HSA-6785807|reactome:R-HSA-8986944 ensembl:ENSG00000176407(gene)|ensembl:ENST00000409785(transcript)|go:"GO:0005576"(extracellular region)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0008270"(zinc ion binding)|go:"GO:0045202"(synapse)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0099536"(synaptic signaling)|go:"GO:1904813"(ficolin-1-rich granule lumen)|interpro:IPR000433(Zinc finger, ZZ-type)|interpro:IPR008598(Drought induced 19)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR039858|interpro:IPR043145|mint:Q9P0J7|reactome:R-HSA-6798695|refseq:NP_064507.3|dip:DIP-47300N go:"GO:0005634"(nucleus) - - figure legend:ST2 F2B|comment:"proteins identified only in induced samples in three MudPIT analyses without BY-adjusted significance (p>0.05), but with t-test significance (p<0.05)"|dataset:Brain Disease - Neurological Diseases & Disorders|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-daoy)|taxid:9606(Homo sapiens DAOY cerebellar medulloblastoma cell line) - 2020/12/29 2020/12/29 rogid:cn8gYfKDpQc8J2ygnqny32sIyyU9606 rogid:g6qsAzE28YlXOJVmsfX8cXe2XUU9606 rigid:rcB/+PMkt3xctqX8BtjneHUykZI false tandem tag:n-n - - - psi-mi:"MI:0658"(multidimensional protein identification technology) psi-mi:"MI:0658"(multidimensional protein identification technology) uniprotkb:P48431 uniprotkb:Q9H0U9 intact:EBI-6124081|uniprotkb:Q14537|ensembl:ENSP00000323588 intact:EBI-2371049|uniprotkb:O75885|uniprotkb:Q5TFE6|ensembl:ENSP00000357597|ensembl:ENSP00000498597 psi-mi:sox2_human(display_long)|uniprotkb:SOX2(gene name)|psi-mi:SOX2(display_short) psi-mi:tsyl1_human(display_long)|uniprotkb:TSPYL1(gene name)|psi-mi:TSPYL1(display_short)|uniprotkb:TSPYL(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Cox et al. (2012) pubmed:23667531|imex:IM-28599 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-26574571|imex:IM-28599-3 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_003097.1|dip:DIP-59913N|ensembl:ENSG00000181449(gene)|ensembl:ENST00000325404(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001649"(osteoblast differentiation)|go:"GO:0001654"(eye development)|go:"GO:0001714"(endodermal cell fate specification)|go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006325"(chromatin organization)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0009611"(response to wounding)|go:"GO:0009653"(anatomical structure morphogenesis)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0021781"(glial cell fate commitment)|go:"GO:0021983"(pituitary gland development)|go:"GO:0021984"(adenohypophysis development)|go:"GO:0022409"(positive regulation of cell-cell adhesion)|go:"GO:0030154"(cell differentiation)|go:"GO:0030900"(forebrain development)|go:"GO:0035019"(somatic stem cell population maintenance)|go:"GO:0035198"(miRNA binding)|go:"GO:0042246"(tissue regeneration)|go:"GO:0043281"(regulation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0043410"(positive regulation of MAPK cascade)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045165"(cell fate commitment)|go:"GO:0045597"(positive regulation of cell differentiation)|go:"GO:0045665"(negative regulation of neuron differentiation)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048839"(inner ear development)|go:"GO:0050680"(negative regulation of epithelial cell proliferation)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0070848"(response to growth factor)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:0097150"(neuronal stem cell population maintenance)|interpro:IPR009071(High mobility group box, HMG)|interpro:IPR022097|interpro:IPR032643|interpro:IPR036910|mint:P48431|rcsb pdb:1O4X|rcsb pdb:2LE4|rcsb pdb:6T7B|rcsb pdb:6T90|rcsb pdb:6WX7|rcsb pdb:6WX8|rcsb pdb:6WX9|rcsb pdb:6YOV|reactome:R-HSA-2892245|reactome:R-HSA-2892247|reactome:R-HSA-3769402|reactome:R-HSA-452723|reactome:R-HSA-6785807|reactome:R-HSA-8986944 refseq:NP_003300.1|ensembl:ENSG00000189241(gene)|ensembl:ENST00000368608(transcript)|ensembl:ENST00000652202(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0006334"(nucleosome assembly)|go:"GO:0019899"(enzyme binding)|go:"GO:0042393"(histone binding)|interpro:IPR002164("Nucleosome assembly protein (NAP)")|interpro:IPR037231|mint:Q9H0U9 go:"GO:0005634"(nucleus) - - figure legend:ST2 F2B|comment:"proteins identified only in induced samples in three MudPIT analyses without BY-adjusted significance (p>0.05), but with t-test significance (p<0.05)"|dataset:Brain Disease - Neurological Diseases & Disorders|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-daoy)|taxid:9606(Homo sapiens DAOY cerebellar medulloblastoma cell line) - 2020/12/29 2020/12/29 rogid:cn8gYfKDpQc8J2ygnqny32sIyyU9606 rogid:wo2DsKIGA3gDmomoBajtGRpQpTQ9606 rigid:rcB/+PMkt3xctqX8BtjneHUykZI false tandem tag:n-n - - - psi-mi:"MI:0658"(multidimensional protein identification technology) psi-mi:"MI:0658"(multidimensional protein identification technology) uniprotkb:P48431 uniprotkb:Q07021 intact:EBI-6124081|uniprotkb:Q14537|ensembl:ENSP00000323588 intact:EBI-347528|uniprotkb:Q2HXR8|uniprotkb:Q9NNY8|intact:EBI-15990352|ensembl:ENSP00000225698 psi-mi:sox2_human(display_long)|uniprotkb:SOX2(gene name)|psi-mi:SOX2(display_short) psi-mi:c1qbp_human(display_long)|uniprotkb:C1QBP(gene name)|psi-mi:C1QBP(display_short)|uniprotkb:GC1QBP(gene name synonym)|uniprotkb:HABP1(gene name synonym)|uniprotkb:SF2P32(gene name synonym)|uniprotkb:Glycoprotein gC1qBP(gene name synonym)|uniprotkb:Hyaluronan-binding protein 1(gene name synonym)|uniprotkb:Mitochondrial matrix protein p32(gene name synonym)|uniprotkb:p33(gene name synonym)|uniprotkb:ASF/SF2-associated protein p32(gene name synonym)|uniprotkb:gC1q-R protein(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Cox et al. (2012) pubmed:23667531|imex:IM-28599 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-26574571|imex:IM-28599-3 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_003097.1|dip:DIP-59913N|ensembl:ENSG00000181449(gene)|ensembl:ENST00000325404(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001649"(osteoblast differentiation)|go:"GO:0001654"(eye development)|go:"GO:0001714"(endodermal cell fate specification)|go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006325"(chromatin organization)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0009611"(response to wounding)|go:"GO:0009653"(anatomical structure morphogenesis)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0021781"(glial cell fate commitment)|go:"GO:0021983"(pituitary gland development)|go:"GO:0021984"(adenohypophysis development)|go:"GO:0022409"(positive regulation of cell-cell adhesion)|go:"GO:0030154"(cell differentiation)|go:"GO:0030900"(forebrain development)|go:"GO:0035019"(somatic stem cell population maintenance)|go:"GO:0035198"(miRNA binding)|go:"GO:0042246"(tissue regeneration)|go:"GO:0043281"(regulation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0043410"(positive regulation of MAPK cascade)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045165"(cell fate commitment)|go:"GO:0045597"(positive regulation of cell differentiation)|go:"GO:0045665"(negative regulation of neuron differentiation)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048839"(inner ear development)|go:"GO:0050680"(negative regulation of epithelial cell proliferation)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0070848"(response to growth factor)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:0097150"(neuronal stem cell population maintenance)|interpro:IPR009071(High mobility group box, HMG)|interpro:IPR022097|interpro:IPR032643|interpro:IPR036910|mint:P48431|rcsb pdb:1O4X|rcsb pdb:2LE4|rcsb pdb:6T7B|rcsb pdb:6T90|rcsb pdb:6WX7|rcsb pdb:6WX8|rcsb pdb:6WX9|rcsb pdb:6YOV|reactome:R-HSA-2892245|reactome:R-HSA-2892247|reactome:R-HSA-3769402|reactome:R-HSA-452723|reactome:R-HSA-6785807|reactome:R-HSA-8986944 refseq:NP_001203.1|dip:DIP-31164N|ensembl:ENSG00000108561(gene)|ensembl:ENST00000225698(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0001849"(complement component C1q complex binding)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0003729"(mRNA binding)|go:"GO:0005080"(protein kinase C binding)|go:"GO:0005540"(hyaluronic acid binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005634"(nucleus)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0006397"(mRNA processing)|go:"GO:0006915"(apoptotic process)|go:"GO:0006955"(immune response)|go:"GO:0006958"(complement activation, classical pathway)|go:"GO:0008134"(transcription factor binding)|go:"GO:0008380"(RNA splicing)|go:"GO:0008494"(translation activator activity)|go:"GO:0009986"(cell surface)|go:"GO:0014065"(phosphatidylinositol 3-kinase signaling)|go:"GO:0016020"(membrane)|go:"GO:0030449"(regulation of complement activation)|go:"GO:0030984"(kininogen binding)|go:"GO:0031690"(adrenergic receptor binding)|go:"GO:0032689"(negative regulation of interferon-gamma production)|go:"GO:0032695"(negative regulation of interleukin-12 production)|go:"GO:0039534"(negative regulation of MDA-5 signaling pathway)|go:"GO:0039536"(negative regulation of RIG-I signaling pathway)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0005829"(cytosol)|go:"GO:0042256"(mature ribosome assembly)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0045087"(innate immune response)|go:"GO:0045785"(positive regulation of cell adhesion)|go:"GO:0048025"(negative regulation of mRNA splicing, via spliceosome)|go:"GO:0048786"(presynaptic active zone)|go:"GO:0050687"(negative regulation of defense response to virus)|go:"GO:0051897"(positive regulation of protein kinase B signaling)|go:"GO:0070131"(positive regulation of mitochondrial translation)|go:"GO:0090023"(positive regulation of neutrophil chemotaxis)|go:"GO:0097177"(mitochondrial ribosome binding)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0098982"(GABA-ergic synapse)|go:"GO:1900026"(positive regulation of substrate adhesion-dependent cell spreading)|go:"GO:1901165"(positive regulation of trophoblast cell migration)|go:"GO:2000510"(positive regulation of dendritic cell chemotaxis)|interpro:IPR003428(Mitochondrial glycoprotein)|interpro:IPR036561|mint:Q07021|rcsb pdb:1P32|rcsb pdb:3RPX|rcsb pdb:6SZW|reactome:R-HSA-111471|go:"GO:0005886"(plasma membrane)|reactome:R-HSA-8980692|reactome:R-HSA-9013106|reactome:R-HSA-9645722|reactome:R-HSA-140837 go:"GO:0005634"(nucleus) - - figure legend:ST2 F2B|comment:"proteins identified only in induced samples in three MudPIT analyses without BY-adjusted significance (p>0.05), but with t-test significance (p<0.05)"|dataset:Brain Disease - Neurological Diseases & Disorders|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-daoy)|taxid:9606(Homo sapiens DAOY cerebellar medulloblastoma cell line) - 2020/12/29 2020/12/29 rogid:cn8gYfKDpQc8J2ygnqny32sIyyU9606 rogid:NfZ31HjbYZxd8UQKRXczhpc306E9606 rigid:rcB/+PMkt3xctqX8BtjneHUykZI false tandem tag:n-n - - - psi-mi:"MI:0658"(multidimensional protein identification technology) psi-mi:"MI:0658"(multidimensional protein identification technology) uniprotkb:P48431 uniprotkb:P78346 intact:EBI-6124081|uniprotkb:Q14537|ensembl:ENSP00000323588 intact:EBI-366553|uniprotkb:B2R799|uniprotkb:E9PB02|ensembl:ENSP00000360768 psi-mi:sox2_human(display_long)|uniprotkb:SOX2(gene name)|psi-mi:SOX2(display_short) psi-mi:rpp30_human(display_long)|uniprotkb:RPP30(gene name)|psi-mi:RPP30(display_short)|uniprotkb:RNASEP2(gene name synonym)|uniprotkb:RNase P subunit 2(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Cox et al. (2012) pubmed:23667531|imex:IM-28599 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-26574571|imex:IM-28599-3 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_003097.1|dip:DIP-59913N|ensembl:ENSG00000181449(gene)|ensembl:ENST00000325404(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001649"(osteoblast differentiation)|go:"GO:0001654"(eye development)|go:"GO:0001714"(endodermal cell fate specification)|go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006325"(chromatin organization)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0009611"(response to wounding)|go:"GO:0009653"(anatomical structure morphogenesis)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0021781"(glial cell fate commitment)|go:"GO:0021983"(pituitary gland development)|go:"GO:0021984"(adenohypophysis development)|go:"GO:0022409"(positive regulation of cell-cell adhesion)|go:"GO:0030154"(cell differentiation)|go:"GO:0030900"(forebrain development)|go:"GO:0035019"(somatic stem cell population maintenance)|go:"GO:0035198"(miRNA binding)|go:"GO:0042246"(tissue regeneration)|go:"GO:0043281"(regulation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0043410"(positive regulation of MAPK cascade)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045165"(cell fate commitment)|go:"GO:0045597"(positive regulation of cell differentiation)|go:"GO:0045665"(negative regulation of neuron differentiation)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048839"(inner ear development)|go:"GO:0050680"(negative regulation of epithelial cell proliferation)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0070848"(response to growth factor)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:0097150"(neuronal stem cell population maintenance)|interpro:IPR009071(High mobility group box, HMG)|interpro:IPR022097|interpro:IPR032643|interpro:IPR036910|mint:P48431|rcsb pdb:1O4X|rcsb pdb:2LE4|rcsb pdb:6T7B|rcsb pdb:6T90|rcsb pdb:6WX7|rcsb pdb:6WX8|rcsb pdb:6WX9|rcsb pdb:6YOV|reactome:R-HSA-2892245|reactome:R-HSA-2892247|reactome:R-HSA-3769402|reactome:R-HSA-452723|reactome:R-HSA-6785807|reactome:R-HSA-8986944 refseq:NP_001098016.1|refseq:NP_006404.1|refseq:XP_011537422.1|refseq:XP_011537423.1|ensembl:ENSG00000148688(gene)|ensembl:ENST00000371703(transcript)|go:"GO:0000172"(ribonuclease MRP complex)|go:"GO:0001682"(tRNA 5'-leader removal)|go:"GO:0003723"(RNA binding)|go:"GO:0004526"(ribonuclease P activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005655"(nucleolar ribonuclease P complex)|go:"GO:0006364"(rRNA processing)|go:"GO:0008033"(tRNA processing)|go:"GO:0030681"(multimeric ribonuclease P complex)|go:"GO:0033204"(ribonuclease P RNA binding)|go:"GO:0090502"(RNA phosphodiester bond hydrolysis, endonucleolytic)|interpro:IPR002738(RNase P subunit p30)|interpro:IPR016195(Polymerase and histidinol phosphatase-like)|mint:P78346|rcsb pdb:6AHR|rcsb pdb:6AHU|reactome:R-HSA-6784531|reactome:R-HSA-6791226|refseq:XP_016870964.1|refseq:XP_016870966.1 go:"GO:0005634"(nucleus) - - figure legend:ST2 F2B|comment:"proteins identified only in induced samples in three MudPIT analyses without BY-adjusted significance (p>0.05), but with t-test significance (p<0.05)"|dataset:Brain Disease - Neurological Diseases & Disorders|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-daoy)|taxid:9606(Homo sapiens DAOY cerebellar medulloblastoma cell line) - 2020/12/29 2020/12/29 rogid:cn8gYfKDpQc8J2ygnqny32sIyyU9606 rogid:pRHvUnpzpNHGzYbS+kRiSa0m71E9606 rigid:rcB/+PMkt3xctqX8BtjneHUykZI false tandem tag:n-n - - - psi-mi:"MI:0658"(multidimensional protein identification technology) psi-mi:"MI:0658"(multidimensional protein identification technology) uniprotkb:P48431 uniprotkb:Q9UKM9 intact:EBI-6124081|uniprotkb:Q14537|ensembl:ENSP00000323588 intact:EBI-714796|uniprotkb:Q14621|uniprotkb:Q2M365|uniprotkb:Q5QPL8|uniprotkb:Q9BQX6|uniprotkb:Q9UJE3|ensembl:ENSP00000246194 psi-mi:sox2_human(display_long)|uniprotkb:SOX2(gene name)|psi-mi:SOX2(display_short) psi-mi:raly_human(display_long)|uniprotkb:hnRNP associated with lethal yellow protein homolog(gene name synonym)|uniprotkb:Autoantigen p542(gene name synonym)|uniprotkb:Heterogeneous nuclear ribonucleoprotein C-like 2(gene name synonym)|uniprotkb:RALY(gene name)|psi-mi:RALY(display_short)|uniprotkb:P542(gene name synonym)|uniprotkb:HNRPCL2(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Cox et al. (2012) pubmed:23667531|imex:IM-28599 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-26574571|imex:IM-28599-3 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_003097.1|dip:DIP-59913N|ensembl:ENSG00000181449(gene)|ensembl:ENST00000325404(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001649"(osteoblast differentiation)|go:"GO:0001654"(eye development)|go:"GO:0001714"(endodermal cell fate specification)|go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006325"(chromatin organization)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0009611"(response to wounding)|go:"GO:0009653"(anatomical structure morphogenesis)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0021781"(glial cell fate commitment)|go:"GO:0021983"(pituitary gland development)|go:"GO:0021984"(adenohypophysis development)|go:"GO:0022409"(positive regulation of cell-cell adhesion)|go:"GO:0030154"(cell differentiation)|go:"GO:0030900"(forebrain development)|go:"GO:0035019"(somatic stem cell population maintenance)|go:"GO:0035198"(miRNA binding)|go:"GO:0042246"(tissue regeneration)|go:"GO:0043281"(regulation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0043410"(positive regulation of MAPK cascade)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045165"(cell fate commitment)|go:"GO:0045597"(positive regulation of cell differentiation)|go:"GO:0045665"(negative regulation of neuron differentiation)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048839"(inner ear development)|go:"GO:0050680"(negative regulation of epithelial cell proliferation)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0070848"(response to growth factor)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:0097150"(neuronal stem cell population maintenance)|interpro:IPR009071(High mobility group box, HMG)|interpro:IPR022097|interpro:IPR032643|interpro:IPR036910|mint:P48431|rcsb pdb:1O4X|rcsb pdb:2LE4|rcsb pdb:6T7B|rcsb pdb:6T90|rcsb pdb:6WX7|rcsb pdb:6WX8|rcsb pdb:6WX9|rcsb pdb:6YOV|reactome:R-HSA-2892245|reactome:R-HSA-2892247|reactome:R-HSA-3769402|reactome:R-HSA-452723|reactome:R-HSA-6785807|reactome:R-HSA-8986944 refseq:XP_011526996.1|refseq:XP_011526997.1|ensembl:ENSG00000125970(gene)|ensembl:ENST00000246194(transcript)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0042632"(cholesterol homeostasis)|go:"GO:0071013"(catalytic step 2 spliceosome)|go:"GO:1903506"(regulation of nucleic acid-templated transcription)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR017347(Heterogeneous nuclear ribonucleoprotein C, Raly)|interpro:IPR034502|interpro:IPR035979|mint:Q9UKM9|rcsb pdb:1WF1|refseq:NP_031393.2|refseq:NP_057951.1|refseq:XP_005260391.1|refseq:XP_005260393.1|refseq:XP_016883220.1 go:"GO:0005634"(nucleus) - - figure legend:ST2 F2B|comment:"proteins identified only in induced samples in three MudPIT analyses without BY-adjusted significance (p>0.05), but with t-test significance (p<0.05)"|dataset:Brain Disease - Neurological Diseases & Disorders|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-daoy)|taxid:9606(Homo sapiens DAOY cerebellar medulloblastoma cell line) - 2020/12/29 2020/12/29 rogid:cn8gYfKDpQc8J2ygnqny32sIyyU9606 rogid:3hd0n2UW0FSRNvSJa2mqflVeorc9606 rigid:rcB/+PMkt3xctqX8BtjneHUykZI false tandem tag:n-n - - - psi-mi:"MI:0658"(multidimensional protein identification technology) psi-mi:"MI:0658"(multidimensional protein identification technology) uniprotkb:P48431 uniprotkb:O43865 intact:EBI-6124081|uniprotkb:Q14537|ensembl:ENSP00000323588 intact:EBI-2371423|uniprotkb:Q2TAJ6|uniprotkb:Q502W8|uniprotkb:Q5VSM0|uniprotkb:Q6P171|uniprotkb:Q96PK4|uniprotkb:Q9UG84|uniprotkb:B4E168|ensembl:ENSP00000358814 psi-mi:sox2_human(display_long)|uniprotkb:SOX2(gene name)|psi-mi:SOX2(display_short) psi-mi:sahh2_human(display_long)|uniprotkb:AHCYL1(gene name)|psi-mi:AHCYL1(display_short)|uniprotkb:DCAL(gene name synonym)|uniprotkb:XPVKONA(gene name synonym)|uniprotkb:S-adenosyl-L-homocysteine hydrolase 2(gene name synonym)|uniprotkb:DC-expressed AHCY-like molecule(gene name synonym)|uniprotkb:Putative adenosylhomocysteinase 2(gene name synonym)|uniprotkb:"IP(3)Rs binding protein released with IP(3)"(gene name synonym)|uniprotkb:IRBIT(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Cox et al. (2012) pubmed:23667531|imex:IM-28599 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-26574571|imex:IM-28599-3 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_003097.1|dip:DIP-59913N|ensembl:ENSG00000181449(gene)|ensembl:ENST00000325404(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001649"(osteoblast differentiation)|go:"GO:0001654"(eye development)|go:"GO:0001714"(endodermal cell fate specification)|go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006325"(chromatin organization)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0009611"(response to wounding)|go:"GO:0009653"(anatomical structure morphogenesis)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0021781"(glial cell fate commitment)|go:"GO:0021983"(pituitary gland development)|go:"GO:0021984"(adenohypophysis development)|go:"GO:0022409"(positive regulation of cell-cell adhesion)|go:"GO:0030154"(cell differentiation)|go:"GO:0030900"(forebrain development)|go:"GO:0035019"(somatic stem cell population maintenance)|go:"GO:0035198"(miRNA binding)|go:"GO:0042246"(tissue regeneration)|go:"GO:0043281"(regulation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0043410"(positive regulation of MAPK cascade)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045165"(cell fate commitment)|go:"GO:0045597"(positive regulation of cell differentiation)|go:"GO:0045665"(negative regulation of neuron differentiation)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048839"(inner ear development)|go:"GO:0050680"(negative regulation of epithelial cell proliferation)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0070848"(response to growth factor)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:0097150"(neuronal stem cell population maintenance)|interpro:IPR009071(High mobility group box, HMG)|interpro:IPR022097|interpro:IPR032643|interpro:IPR036910|mint:P48431|rcsb pdb:1O4X|rcsb pdb:2LE4|rcsb pdb:6T7B|rcsb pdb:6T90|rcsb pdb:6WX7|rcsb pdb:6WX8|rcsb pdb:6WX9|rcsb pdb:6YOV|reactome:R-HSA-2892245|reactome:R-HSA-2892247|reactome:R-HSA-3769402|reactome:R-HSA-452723|reactome:R-HSA-6785807|reactome:R-HSA-8986944 refseq:NP_001229602.1|refseq:NP_001229603.1|refseq:NP_001229604.1|refseq:NP_001229605.1|refseq:NP_006612.2|ensembl:ENSG00000168710(gene)|ensembl:ENST00000369799(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005829"(cytosol)|go:"GO:0006378"(mRNA polyadenylation)|go:"GO:0006611"(protein export from nucleus)|go:"GO:0006730"(one-carbon metabolic process)|go:"GO:0006915"(apoptotic process)|go:"GO:0010765"(positive regulation of sodium ion transport)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0031440"(regulation of mRNA 3'-end processing)|go:"GO:0032412"(regulation of ion transmembrane transporter activity)|go:"GO:0033353"(S-adenosylmethionine cycle)|go:"GO:0038166"(angiotensin-activated signaling pathway)|go:"GO:0042045"(epithelial fluid transport)|go:"GO:0042802"(identical protein binding)|go:"GO:0044070"(regulation of anion transport)|go:"GO:0044233"(mitochondria-associated endoplasmic reticulum membrane)|go:"GO:0051592"(response to calcium ion)|go:"GO:0070062"(extracellular exosome)|go:"GO:1990456"(mitochondrion-endoplasmic reticulum membrane tethering)|interpro:IPR000043(S-adenosyl-L-homocysteine hydrolase)|interpro:IPR015878(S-adenosyl-L-homocysteine hydrolase, NAD binding)|interpro:IPR020082|interpro:IPR036291|interpro:IPR042172|mint:O43865|rcsb pdb:3MTG|reactome:R-HSA-112043|reactome:R-HSA-1489509|reactome:R-HSA-2029485|reactome:R-HSA-2871809|reactome:R-HSA-422356|reactome:R-HSA-5218921|reactome:R-HSA-5578775|reactome:R-HSA-5607763|reactome:R-HSA-9664323|reactome:R-HSA-983695 go:"GO:0005634"(nucleus) - - figure legend:ST2 F2B|comment:"proteins identified only in induced samples in three MudPIT analyses without BY-adjusted significance (p>0.05), but with t-test significance (p<0.05)"|dataset:Brain Disease - Neurological Diseases & Disorders|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-daoy)|taxid:9606(Homo sapiens DAOY cerebellar medulloblastoma cell line) - 2020/12/29 2020/12/29 rogid:cn8gYfKDpQc8J2ygnqny32sIyyU9606 rogid:uwZ+P9SdKadoVn01p/b8qHp6egk9606 rigid:rcB/+PMkt3xctqX8BtjneHUykZI false tandem tag:n-n - - - psi-mi:"MI:0658"(multidimensional protein identification technology) psi-mi:"MI:0658"(multidimensional protein identification technology) uniprotkb:P48431 uniprotkb:Q9UL63 intact:EBI-6124081|uniprotkb:Q14537|ensembl:ENSP00000323588 intact:EBI-1048053|uniprotkb:A4D1M8|uniprotkb:A6NG43|uniprotkb:Q9NSK4|uniprotkb:Q9NUS8|ensembl:ENSP00000323527 psi-mi:sox2_human(display_long)|uniprotkb:SOX2(gene name)|psi-mi:SOX2(display_short) psi-mi:mkln1_human(display_long)|uniprotkb:MKLN1(gene name)|psi-mi:MKLN1(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Cox et al. (2012) pubmed:23667531|imex:IM-28599 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-26574571|imex:IM-28599-3 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_003097.1|dip:DIP-59913N|ensembl:ENSG00000181449(gene)|ensembl:ENST00000325404(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001649"(osteoblast differentiation)|go:"GO:0001654"(eye development)|go:"GO:0001714"(endodermal cell fate specification)|go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006325"(chromatin organization)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0009611"(response to wounding)|go:"GO:0009653"(anatomical structure morphogenesis)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0021781"(glial cell fate commitment)|go:"GO:0021983"(pituitary gland development)|go:"GO:0021984"(adenohypophysis development)|go:"GO:0022409"(positive regulation of cell-cell adhesion)|go:"GO:0030154"(cell differentiation)|go:"GO:0030900"(forebrain development)|go:"GO:0035019"(somatic stem cell population maintenance)|go:"GO:0035198"(miRNA binding)|go:"GO:0042246"(tissue regeneration)|go:"GO:0043281"(regulation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0043410"(positive regulation of MAPK cascade)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045165"(cell fate commitment)|go:"GO:0045597"(positive regulation of cell differentiation)|go:"GO:0045665"(negative regulation of neuron differentiation)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048839"(inner ear development)|go:"GO:0050680"(negative regulation of epithelial cell proliferation)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0070848"(response to growth factor)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:0097150"(neuronal stem cell population maintenance)|interpro:IPR009071(High mobility group box, HMG)|interpro:IPR022097|interpro:IPR032643|interpro:IPR036910|mint:P48431|rcsb pdb:1O4X|rcsb pdb:2LE4|rcsb pdb:6T7B|rcsb pdb:6T90|rcsb pdb:6WX7|rcsb pdb:6WX8|rcsb pdb:6WX9|rcsb pdb:6YOV|reactome:R-HSA-2892245|reactome:R-HSA-2892247|reactome:R-HSA-3769402|reactome:R-HSA-452723|reactome:R-HSA-6785807|reactome:R-HSA-8986944 refseq:NP_001138826.1|refseq:NP_037387.2|ensembl:ENSG00000128585(gene)|ensembl:ENST00000352689(transcript)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0001726"(ruffle)|go:"GO:0002090"(regulation of receptor internalization)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005938"(cell cortex)|go:"GO:0007160"(cell-matrix adhesion)|go:"GO:0007165"(signal transduction)|go:"GO:0008360"(regulation of cell shape)|go:"GO:0031532"(actin cytoskeleton reorganization)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0098794"(postsynapse)|interpro:IPR006594(LisH dimerisation motif)|interpro:IPR006595(CTLH, C-terminal to LisH motif)|interpro:IPR006652(Kelch repeat type 1)|interpro:IPR008979(Galactose-binding like)|interpro:IPR010565(Muskelin, N-terminal)|interpro:IPR011043(Galactose oxidase/kelch, beta-propeller)|interpro:IPR015915(Kelch-type beta propeller)|mint:Q9UL63|refseq:NP_001308245.1 go:"GO:0005634"(nucleus) - - figure legend:ST2 F2B|comment:"proteins identified only in induced samples in three MudPIT analyses without BY-adjusted significance (p>0.05), but with t-test significance (p<0.05)"|dataset:Brain Disease - Neurological Diseases & Disorders|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-daoy)|taxid:9606(Homo sapiens DAOY cerebellar medulloblastoma cell line) - 2020/12/29 2020/12/29 rogid:cn8gYfKDpQc8J2ygnqny32sIyyU9606 rogid:7yT0576+rLpdpgT/cqXPEuf80/g9606 rigid:rcB/+PMkt3xctqX8BtjneHUykZI false tandem tag:n-n - - - psi-mi:"MI:0658"(multidimensional protein identification technology) psi-mi:"MI:0658"(multidimensional protein identification technology) uniprotkb:P48431 uniprotkb:Q99733 intact:EBI-6124081|uniprotkb:Q14537|ensembl:ENSP00000323588 intact:EBI-2255116|uniprotkb:B2R6J4|uniprotkb:F5HFY4|ensembl:ENSP00000369915|ensembl:ENSP00000483728 psi-mi:sox2_human(display_long)|uniprotkb:SOX2(gene name)|psi-mi:SOX2(display_short) psi-mi:np1l4_human(display_long)|uniprotkb:NAP1L4(gene name)|psi-mi:NAP1L4(display_short)|uniprotkb:NAP2(gene name synonym)|uniprotkb:Nucleosome assembly protein 2(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Cox et al. (2012) pubmed:23667531|imex:IM-28599 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-26574571|imex:IM-28599-3 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_003097.1|dip:DIP-59913N|ensembl:ENSG00000181449(gene)|ensembl:ENST00000325404(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001649"(osteoblast differentiation)|go:"GO:0001654"(eye development)|go:"GO:0001714"(endodermal cell fate specification)|go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006325"(chromatin organization)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0009611"(response to wounding)|go:"GO:0009653"(anatomical structure morphogenesis)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0021781"(glial cell fate commitment)|go:"GO:0021983"(pituitary gland development)|go:"GO:0021984"(adenohypophysis development)|go:"GO:0022409"(positive regulation of cell-cell adhesion)|go:"GO:0030154"(cell differentiation)|go:"GO:0030900"(forebrain development)|go:"GO:0035019"(somatic stem cell population maintenance)|go:"GO:0035198"(miRNA binding)|go:"GO:0042246"(tissue regeneration)|go:"GO:0043281"(regulation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0043410"(positive regulation of MAPK cascade)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045165"(cell fate commitment)|go:"GO:0045597"(positive regulation of cell differentiation)|go:"GO:0045665"(negative regulation of neuron differentiation)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048839"(inner ear development)|go:"GO:0050680"(negative regulation of epithelial cell proliferation)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0070848"(response to growth factor)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:0097150"(neuronal stem cell population maintenance)|interpro:IPR009071(High mobility group box, HMG)|interpro:IPR022097|interpro:IPR032643|interpro:IPR036910|mint:P48431|rcsb pdb:1O4X|rcsb pdb:2LE4|rcsb pdb:6T7B|rcsb pdb:6T90|rcsb pdb:6WX7|rcsb pdb:6WX8|rcsb pdb:6WX9|rcsb pdb:6YOV|reactome:R-HSA-2892245|reactome:R-HSA-2892247|reactome:R-HSA-3769402|reactome:R-HSA-452723|reactome:R-HSA-6785807|reactome:R-HSA-8986944 refseq:NP_005960.1|ensembl:ENSG00000205531(gene)|ensembl:ENSG00000273562(gene)|ensembl:ENST00000380542(transcript)|ensembl:ENST00000619695(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0003682"(chromatin binding)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006334"(nucleosome assembly)|go:"GO:0031491"(nucleosome binding)|go:"GO:0042393"(histone binding)|go:"GO:0051082"(unfolded protein binding)|interpro:IPR002164("Nucleosome assembly protein (NAP)")|interpro:IPR037231|mint:Q99733 go:"GO:0005634"(nucleus) - - figure legend:ST2 F2B|comment:"proteins identified only in induced samples in three MudPIT analyses without BY-adjusted significance (p>0.05), but with t-test significance (p<0.05)"|dataset:Brain Disease - Neurological Diseases & Disorders|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-daoy)|taxid:9606(Homo sapiens DAOY cerebellar medulloblastoma cell line) - 2020/12/29 2020/12/29 rogid:cn8gYfKDpQc8J2ygnqny32sIyyU9606 rogid:tES8IJDlW4JONR/pdC8dq49I/7Y9606 rigid:rcB/+PMkt3xctqX8BtjneHUykZI false tandem tag:n-n - - - psi-mi:"MI:0658"(multidimensional protein identification technology) psi-mi:"MI:0658"(multidimensional protein identification technology) uniprotkb:P48431 uniprotkb:O14497 intact:EBI-6124081|uniprotkb:Q14537|ensembl:ENSP00000323588 intact:EBI-637887|intact:EBI-28988406|ensembl:ENSP00000320485|uniprotkb:D3DPL1|uniprotkb:Q53FK9|uniprotkb:Q5T0W1|uniprotkb:Q5T0W2|uniprotkb:Q5T0W3|uniprotkb:Q8NFD6|uniprotkb:Q96T89|uniprotkb:Q9BY33|uniprotkb:Q9HBJ5|uniprotkb:Q9UPZ1 psi-mi:sox2_human(display_long)|uniprotkb:SOX2(gene name)|psi-mi:SOX2(display_short) psi-mi:ari1a_human(display_long)|uniprotkb:hELD(gene name synonym)|uniprotkb:SWI/SNF-related, matrix-associated, actin-dependent regulator of chromatin subfamily F member 1(gene name synonym)|uniprotkb:SWI/SNF complex protein p270(gene name synonym)|uniprotkb:B120(gene name synonym)|uniprotkb:SWI-like protein(gene name synonym)|uniprotkb:Osa homolog 1(gene name synonym)|uniprotkb:BRG1-associated factor 250(gene name synonym)|uniprotkb:BRG1-associated factor 250a(gene name synonym)|uniprotkb:ARID1A(gene name)|psi-mi:ARID1A(display_short)|uniprotkb:C1orf4(gene name synonym)|uniprotkb:SMARCF1(gene name synonym)|uniprotkb:OSA1(gene name synonym)|uniprotkb:BAF250(gene name synonym)|uniprotkb:BAF250A(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Cox et al. (2012) pubmed:23667531|imex:IM-28599 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-26574619|imex:IM-28599-5 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_003097.1|dip:DIP-59913N|ensembl:ENSG00000181449(gene)|ensembl:ENST00000325404(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001649"(osteoblast differentiation)|go:"GO:0001654"(eye development)|go:"GO:0001714"(endodermal cell fate specification)|go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006325"(chromatin organization)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0009611"(response to wounding)|go:"GO:0009653"(anatomical structure morphogenesis)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0021781"(glial cell fate commitment)|go:"GO:0021983"(pituitary gland development)|go:"GO:0021984"(adenohypophysis development)|go:"GO:0022409"(positive regulation of cell-cell adhesion)|go:"GO:0030154"(cell differentiation)|go:"GO:0030900"(forebrain development)|go:"GO:0035019"(somatic stem cell population maintenance)|go:"GO:0035198"(miRNA binding)|go:"GO:0042246"(tissue regeneration)|go:"GO:0043281"(regulation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0043410"(positive regulation of MAPK cascade)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045165"(cell fate commitment)|go:"GO:0045597"(positive regulation of cell differentiation)|go:"GO:0045665"(negative regulation of neuron differentiation)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048839"(inner ear development)|go:"GO:0050680"(negative regulation of epithelial cell proliferation)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0070848"(response to growth factor)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:0097150"(neuronal stem cell population maintenance)|interpro:IPR009071(High mobility group box, HMG)|interpro:IPR022097|interpro:IPR032643|interpro:IPR036910|mint:P48431|rcsb pdb:1O4X|rcsb pdb:2LE4|rcsb pdb:6T7B|rcsb pdb:6T90|rcsb pdb:6WX7|rcsb pdb:6WX8|rcsb pdb:6WX9|rcsb pdb:6YOV|reactome:R-HSA-2892245|reactome:R-HSA-2892247|reactome:R-HSA-3769402|reactome:R-HSA-452723|reactome:R-HSA-6785807|reactome:R-HSA-8986944 reactome:R-HSA-3214858|reactome:R-HSA-8939243|go:"GO:0005634"(nucleus)|ensembl:ENSG00000117713(gene)|go:"GO:0005654"(nucleoplasm)|ensembl:ENST00000324856(transcript)|go:"GO:0006337"(nucleosome disassembly)|go:"GO:0000785"(chromatin)|go:"GO:0003677"(DNA binding)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007399"(nervous system development)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0016514"(SWI/SNF complex)|go:"GO:0016922"(nuclear receptor binding)|go:"GO:0030520"(intracellular estrogen receptor signaling pathway)|go:"GO:0030521"(androgen receptor signaling pathway)|go:"GO:0035060"(brahma complex)|go:"GO:0042766"(nucleosome mobilization)|go:"GO:0042921"(glucocorticoid receptor signaling pathway)|go:"GO:0043044"|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0048096"|go:"GO:0071564"(npBAF complex)|go:"GO:0071565"(nBAF complex)|interpro:IPR001606(AT-rich interaction region)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR021906|interpro:IPR030094|interpro:IPR033388|interpro:IPR036431|mint:O14497|rcsb pdb:1RYU|rcsb pdb:6LTH|rcsb pdb:6LTJ|refseq:NP_006006.3|refseq:NP_624361.1|dip:DIP-33016N|ensembl:ENSP00000320485|ensembl:ENST00000374152|ensembl:ENSP00000363267|ensembl:ENST00000457599|ensembl:ENSP00000387636 go:"GO:0005634"(nucleus) - - figure legend:ST2 F2A|comment:proteins identified only in our induced samples in three MudPIT analyses with the more stringent BY-adjusted significance p<0.05|dataset:Brain Disease - Neurological Diseases & Disorders|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-daoy)|taxid:9606(Homo sapiens DAOY cerebellar medulloblastoma cell line) - 2020/12/29 2020/12/29 rogid:cn8gYfKDpQc8J2ygnqny32sIyyU9606 rogid:C3ZRlsnBUZV6SBEbISRImamhzoQ9606 rigid:6EMs5+B89Q89RCR/2S2BG6PhH9E false tandem tag:n-n - - - psi-mi:"MI:0658"(multidimensional protein identification technology) psi-mi:"MI:0658"(multidimensional protein identification technology) uniprotkb:P48431 uniprotkb:P51531 intact:EBI-6124081|uniprotkb:Q14537|ensembl:ENSP00000323588 intact:EBI-679562|uniprotkb:B1ALG3|uniprotkb:B1ALG4|uniprotkb:D3DRH4|uniprotkb:D3DRH5|ensembl:ENSP00000265773|ensembl:ENSP00000371638 psi-mi:sox2_human(display_long)|uniprotkb:SOX2(gene name)|psi-mi:SOX2(display_short) psi-mi:smca2_human(display_long)|uniprotkb:ATP-dependent helicase SMARCA2(gene name synonym)|uniprotkb:SNF2-alpha(gene name synonym)|uniprotkb:SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 2(gene name synonym)|uniprotkb:SMARCA2(gene name)|psi-mi:SMARCA2(display_short)|uniprotkb:BRM(gene name synonym)|uniprotkb:SNF2A(gene name synonym)|uniprotkb:SNF2L2(gene name synonym)|uniprotkb:BAF190B(gene name synonym)|uniprotkb:Protein brahma homolog(gene name synonym)|uniprotkb:BRG1-associated factor 190B(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Cox et al. (2012) pubmed:23667531|imex:IM-28599 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-26574619|imex:IM-28599-5 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_003097.1|dip:DIP-59913N|ensembl:ENSG00000181449(gene)|ensembl:ENST00000325404(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001649"(osteoblast differentiation)|go:"GO:0001654"(eye development)|go:"GO:0001714"(endodermal cell fate specification)|go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006325"(chromatin organization)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0009611"(response to wounding)|go:"GO:0009653"(anatomical structure morphogenesis)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0021781"(glial cell fate commitment)|go:"GO:0021983"(pituitary gland development)|go:"GO:0021984"(adenohypophysis development)|go:"GO:0022409"(positive regulation of cell-cell adhesion)|go:"GO:0030154"(cell differentiation)|go:"GO:0030900"(forebrain development)|go:"GO:0035019"(somatic stem cell population maintenance)|go:"GO:0035198"(miRNA binding)|go:"GO:0042246"(tissue regeneration)|go:"GO:0043281"(regulation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0043410"(positive regulation of MAPK cascade)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045165"(cell fate commitment)|go:"GO:0045597"(positive regulation of cell differentiation)|go:"GO:0045665"(negative regulation of neuron differentiation)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048839"(inner ear development)|go:"GO:0050680"(negative regulation of epithelial cell proliferation)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0070848"(response to growth factor)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:0097150"(neuronal stem cell population maintenance)|interpro:IPR009071(High mobility group box, HMG)|interpro:IPR022097|interpro:IPR032643|interpro:IPR036910|mint:P48431|rcsb pdb:1O4X|rcsb pdb:2LE4|rcsb pdb:6T7B|rcsb pdb:6T90|rcsb pdb:6WX7|rcsb pdb:6WX8|rcsb pdb:6WX9|rcsb pdb:6YOV|reactome:R-HSA-2892245|reactome:R-HSA-2892247|reactome:R-HSA-3769402|reactome:R-HSA-452723|reactome:R-HSA-6785807|reactome:R-HSA-8986944 refseq:NP_003061.3|refseq:NP_620614.2|refseq:NP_001276325.1|refseq:NP_001276326.1|dip:DIP-29005N|ensembl:ENSG00000080503(gene)|ensembl:ENST00000349721(transcript)|ensembl:ENST00000382203(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0004386"(helicase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007286"(spermatid development)|go:"GO:0007399"(nervous system development)|go:"GO:0008094"(ATP-dependent activity, acting on DNA)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0016514"(SWI/SNF complex)|go:"GO:0016787"(hydrolase activity)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0042393"(histone binding)|go:"GO:0043044"|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0045111"(intermediate filament cytoskeleton)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0070615"|go:"GO:0071564"(npBAF complex)|go:"GO:0071565"(nBAF complex)|interpro:IPR000330(SNF2-related)|interpro:IPR001487(Bromodomain)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR006576(BRK)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR014012(Helicase/SANT-associated, DNA binding)|interpro:IPR014978(QLQ)|interpro:IPR018359|interpro:IPR027417|interpro:IPR029295|interpro:IPR030088|interpro:IPR036427|interpro:IPR037259|interpro:IPR038718|mint:P51531|rcsb pdb:2DAT|rcsb pdb:4QY4|rcsb pdb:5DKC|rcsb pdb:5DKH|rcsb pdb:6EG2|rcsb pdb:6EG3|rcsb pdb:6HAX|rcsb pdb:6HAY|rcsb pdb:6HAZ|reactome:R-HSA-3214858|reactome:R-HSA-8939243 go:"GO:0005634"(nucleus) - - figure legend:ST2 F2A|comment:proteins identified only in our induced samples in three MudPIT analyses with the more stringent BY-adjusted significance p<0.05|dataset:Brain Disease - Neurological Diseases & Disorders|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-daoy)|taxid:9606(Homo sapiens DAOY cerebellar medulloblastoma cell line) - 2020/12/29 2020/12/29 rogid:cn8gYfKDpQc8J2ygnqny32sIyyU9606 rogid:DmQot4h4SmtqmUGBgF5ictTah289606 rigid:6EMs5+B89Q89RCR/2S2BG6PhH9E false tandem tag:n-n - - - psi-mi:"MI:0658"(multidimensional protein identification technology) psi-mi:"MI:0658"(multidimensional protein identification technology) uniprotkb:P48431 uniprotkb:P10644 intact:EBI-6124081|uniprotkb:Q14537|ensembl:ENSP00000323588 intact:EBI-476431|uniprotkb:Q567S7|uniprotkb:K7ER48|ensembl:ENSP00000351410|ensembl:ENSP00000376475|ensembl:ENSP00000445625|ensembl:ENSP00000464977|ensembl:ENSP00000466459 psi-mi:sox2_human(display_long)|uniprotkb:SOX2(gene name)|psi-mi:SOX2(display_short) psi-mi:kap0_human(display_long)|uniprotkb:Tissue-specific extinguisher 1(gene name synonym)|uniprotkb:PRKAR1A(gene name)|psi-mi:PRKAR1A(display_short)|uniprotkb:PKR1(gene name synonym)|uniprotkb:PRKAR1(gene name synonym)|uniprotkb:TSE1(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Cox et al. (2012) pubmed:23667531|imex:IM-28599 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-26574619|imex:IM-28599-5 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_003097.1|dip:DIP-59913N|ensembl:ENSG00000181449(gene)|ensembl:ENST00000325404(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001649"(osteoblast differentiation)|go:"GO:0001654"(eye development)|go:"GO:0001714"(endodermal cell fate specification)|go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006325"(chromatin organization)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0009611"(response to wounding)|go:"GO:0009653"(anatomical structure morphogenesis)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0021781"(glial cell fate commitment)|go:"GO:0021983"(pituitary gland development)|go:"GO:0021984"(adenohypophysis development)|go:"GO:0022409"(positive regulation of cell-cell adhesion)|go:"GO:0030154"(cell differentiation)|go:"GO:0030900"(forebrain development)|go:"GO:0035019"(somatic stem cell population maintenance)|go:"GO:0035198"(miRNA binding)|go:"GO:0042246"(tissue regeneration)|go:"GO:0043281"(regulation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0043410"(positive regulation of MAPK cascade)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045165"(cell fate commitment)|go:"GO:0045597"(positive regulation of cell differentiation)|go:"GO:0045665"(negative regulation of neuron differentiation)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048839"(inner ear development)|go:"GO:0050680"(negative regulation of epithelial cell proliferation)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0070848"(response to growth factor)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:0097150"(neuronal stem cell population maintenance)|interpro:IPR009071(High mobility group box, HMG)|interpro:IPR022097|interpro:IPR032643|interpro:IPR036910|mint:P48431|rcsb pdb:1O4X|rcsb pdb:2LE4|rcsb pdb:6T7B|rcsb pdb:6T90|rcsb pdb:6WX7|rcsb pdb:6WX8|rcsb pdb:6WX9|rcsb pdb:6YOV|reactome:R-HSA-2892245|reactome:R-HSA-2892247|reactome:R-HSA-3769402|reactome:R-HSA-452723|reactome:R-HSA-6785807|reactome:R-HSA-8986944 refseq:NP_002725.1|refseq:NP_997636.1|refseq:NP_997637.1|refseq:XP_011523285.1|refseq:XP_011523286.1|refseq:XP_011523287.1|refseq:NP_001263218.1|refseq:NP_001263219.1|refseq:NP_001265362.1|dip:DIP-34368N|ensembl:ENSG00000108946(gene)|ensembl:ENST00000358598(transcript)|ensembl:ENST00000392711(transcript)|ensembl:ENST00000536854(transcript)|ensembl:ENST00000586397(transcript)|ensembl:ENST00000589228(transcript)|go:"GO:0001707"(mesoderm formation)|go:"GO:0004862"(cAMP-dependent protein kinase inhibitor activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005771"(multivesicular body)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005952"(cAMP-dependent protein kinase complex)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007143"(female meiotic nuclear division)|go:"GO:0008603"(cAMP-dependent protein kinase regulator activity)|go:"GO:0010738"(regulation of protein kinase A signaling)|go:"GO:0016020"(membrane)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030552"(cAMP binding)|go:"GO:0031588"(nucleotide-activated protein kinase complex)|go:"GO:0031594"(neuromuscular junction)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034236"(protein kinase A catalytic subunit binding)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0043949"(regulation of cAMP-mediated signaling)|go:"GO:0044853"(plasma membrane raft)|go:"GO:0045214"(sarcomere organization)|go:"GO:0045835"(negative regulation of meiotic nuclear division)|go:"GO:0046007"(negative regulation of activated T cell proliferation)|go:"GO:0060038"(cardiac muscle cell proliferation)|go:"GO:0097224"(sperm connecting piece)|go:"GO:0097546"(ciliary base)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:2000480"(negative regulation of cAMP-dependent protein kinase activity)|interpro:IPR000595(Cyclic nucleotide-binding)|interpro:IPR003117(cAMP-dependent protein kinase, regulatory subunit, type I/II alpha/beta)|interpro:IPR012198(cAMP-dependent protein kinase regulatory subunit)|interpro:IPR014710(RmlC-like jelly roll fold)|interpro:IPR018488|rcsb pdb:5KJZ|reactome:R-HSA-163615|reactome:R-HSA-164378|reactome:R-HSA-180024|reactome:R-HSA-381676|reactome:R-HSA-432040|reactome:R-HSA-442720|reactome:R-HSA-5610787|reactome:R-HSA-9660821|reactome:R-HSA-9664323|reactome:R-HSA-983231|interpro:IPR018490|mint:P10644|rcsb pdb:5KJX|rcsb pdb:5KJY go:"GO:0005634"(nucleus) - - figure legend:ST2 F2A|comment:proteins identified only in our induced samples in three MudPIT analyses with the more stringent BY-adjusted significance p<0.05|dataset:Brain Disease - Neurological Diseases & Disorders|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-daoy)|taxid:9606(Homo sapiens DAOY cerebellar medulloblastoma cell line) - 2020/12/29 2020/12/29 rogid:cn8gYfKDpQc8J2ygnqny32sIyyU9606 rogid:dUZaCJQnC0KZEG4pccIqoT066VY9606 rigid:6EMs5+B89Q89RCR/2S2BG6PhH9E false tandem tag:n-n - - - psi-mi:"MI:0658"(multidimensional protein identification technology) psi-mi:"MI:0658"(multidimensional protein identification technology) uniprotkb:P48431 uniprotkb:Q8NG31 intact:EBI-6124081|uniprotkb:Q14537|ensembl:ENSP00000323588 intact:EBI-1001161|intact:EBI-2555927|uniprotkb:Q8NHE1|uniprotkb:Q8WXA6|uniprotkb:Q9HCK2|uniprotkb:Q9NR92|ensembl:ENSP00000335463 psi-mi:sox2_human(display_long)|uniprotkb:SOX2(gene name)|psi-mi:SOX2(display_short) psi-mi:knl1_human(display_long)|uniprotkb:KNL1(gene name)|psi-mi:KNL1(display_short)|uniprotkb:ALL1-fused gene from chromosome 15q14 protein(gene name synonym)|uniprotkb:Bub-linking kinetochore protein(gene name synonym)|uniprotkb:CASC5(gene name synonym)|uniprotkb:Cancer susceptibility candidate gene 5 protein(gene name synonym)|uniprotkb:Cancer/testis antigen 29(gene name synonym)|uniprotkb:KIAA1570(gene name synonym)|uniprotkb:Kinetochore-null protein 1(gene name synonym)|uniprotkb:Protein CASC5(gene name synonym)|uniprotkb:Protein D40/AF15q14(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Cox et al. (2012) pubmed:23667531|imex:IM-28599 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-26574619|imex:IM-28599-5 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_003097.1|dip:DIP-59913N|ensembl:ENSG00000181449(gene)|ensembl:ENST00000325404(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001649"(osteoblast differentiation)|go:"GO:0001654"(eye development)|go:"GO:0001714"(endodermal cell fate specification)|go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006325"(chromatin organization)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0009611"(response to wounding)|go:"GO:0009653"(anatomical structure morphogenesis)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0021781"(glial cell fate commitment)|go:"GO:0021983"(pituitary gland development)|go:"GO:0021984"(adenohypophysis development)|go:"GO:0022409"(positive regulation of cell-cell adhesion)|go:"GO:0030154"(cell differentiation)|go:"GO:0030900"(forebrain development)|go:"GO:0035019"(somatic stem cell population maintenance)|go:"GO:0035198"(miRNA binding)|go:"GO:0042246"(tissue regeneration)|go:"GO:0043281"(regulation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0043410"(positive regulation of MAPK cascade)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045165"(cell fate commitment)|go:"GO:0045597"(positive regulation of cell differentiation)|go:"GO:0045665"(negative regulation of neuron differentiation)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048839"(inner ear development)|go:"GO:0050680"(negative regulation of epithelial cell proliferation)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0070848"(response to growth factor)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:0097150"(neuronal stem cell population maintenance)|interpro:IPR009071(High mobility group box, HMG)|interpro:IPR022097|interpro:IPR032643|interpro:IPR036910|mint:P48431|rcsb pdb:1O4X|rcsb pdb:2LE4|rcsb pdb:6T7B|rcsb pdb:6T90|rcsb pdb:6WX7|rcsb pdb:6WX8|rcsb pdb:6WX9|rcsb pdb:6YOV|reactome:R-HSA-2892245|reactome:R-HSA-2892247|reactome:R-HSA-3769402|reactome:R-HSA-452723|reactome:R-HSA-6785807|reactome:R-HSA-8986944 ensembl:ENSG00000137812(gene)|ensembl:ENST00000346991(transcript)|go:"GO:0000776"(kinetochore)|go:"GO:0001669"(acrosomal vesicle)|go:"GO:0001675"(acrosome assembly)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0008608"(attachment of spindle microtubules to kinetochore)|go:"GO:0016604"(nuclear body)|go:"GO:0034501"(protein localization to kinetochore)|go:"GO:0051301"(cell division)|interpro:IPR037388|interpro:IPR040850|interpro:IPR043651|mint:Q8NG31|rcsb pdb:3SI5|rcsb pdb:4A1G|rcsb pdb:4NF9|rcsb pdb:4NFA|reactome:R-HSA-141444|reactome:R-HSA-2467813|reactome:R-HSA-2500257|reactome:R-HSA-5663220|reactome:R-HSA-606279|reactome:R-HSA-68877|reactome:R-HSA-9648025|refseq:NP_653091.3|refseq:NP_733468.3|ensembl:ENSP00000335463|ensembl:ENST00000399668|ensembl:ENSP00000382576|dip:DIP-36474N go:"GO:0005634"(nucleus) - - figure legend:ST2 F2A|comment:proteins identified only in our induced samples in three MudPIT analyses with the more stringent BY-adjusted significance p<0.05|dataset:Brain Disease - Neurological Diseases & Disorders|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-daoy)|taxid:9606(Homo sapiens DAOY cerebellar medulloblastoma cell line) - 2020/12/29 2020/12/29 rogid:cn8gYfKDpQc8J2ygnqny32sIyyU9606 rogid:VrKgxXm7DGkpFhJjZ98oQhkr5Eo9606 rigid:6EMs5+B89Q89RCR/2S2BG6PhH9E false tandem tag:n-n - - - psi-mi:"MI:0658"(multidimensional protein identification technology) psi-mi:"MI:0658"(multidimensional protein identification technology) uniprotkb:P48431 uniprotkb:Q02086 intact:EBI-6124081|uniprotkb:Q14537|ensembl:ENSP00000323588 intact:EBI-8651703|intact:MINT-8163914|uniprotkb:A6NK74|ensembl:ENSP00000365931 psi-mi:sox2_human(display_long)|uniprotkb:SOX2(gene name)|psi-mi:SOX2(display_short) psi-mi:sp2_human(display_long)|uniprotkb:SP2(gene name)|psi-mi:SP2(display_short)|uniprotkb:KIAA0048(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Cox et al. (2012) pubmed:23667531|imex:IM-28599 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-26574619|imex:IM-28599-5 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_003097.1|dip:DIP-59913N|ensembl:ENSG00000181449(gene)|ensembl:ENST00000325404(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001649"(osteoblast differentiation)|go:"GO:0001654"(eye development)|go:"GO:0001714"(endodermal cell fate specification)|go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006325"(chromatin organization)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0009611"(response to wounding)|go:"GO:0009653"(anatomical structure morphogenesis)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0021781"(glial cell fate commitment)|go:"GO:0021983"(pituitary gland development)|go:"GO:0021984"(adenohypophysis development)|go:"GO:0022409"(positive regulation of cell-cell adhesion)|go:"GO:0030154"(cell differentiation)|go:"GO:0030900"(forebrain development)|go:"GO:0035019"(somatic stem cell population maintenance)|go:"GO:0035198"(miRNA binding)|go:"GO:0042246"(tissue regeneration)|go:"GO:0043281"(regulation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0043410"(positive regulation of MAPK cascade)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045165"(cell fate commitment)|go:"GO:0045597"(positive regulation of cell differentiation)|go:"GO:0045665"(negative regulation of neuron differentiation)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048839"(inner ear development)|go:"GO:0050680"(negative regulation of epithelial cell proliferation)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0070848"(response to growth factor)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:0097150"(neuronal stem cell population maintenance)|interpro:IPR009071(High mobility group box, HMG)|interpro:IPR022097|interpro:IPR032643|interpro:IPR036910|mint:P48431|rcsb pdb:1O4X|rcsb pdb:2LE4|rcsb pdb:6T7B|rcsb pdb:6T90|rcsb pdb:6WX7|rcsb pdb:6WX8|rcsb pdb:6WX9|rcsb pdb:6YOV|reactome:R-HSA-2892245|reactome:R-HSA-2892247|reactome:R-HSA-3769402|reactome:R-HSA-452723|reactome:R-HSA-6785807|reactome:R-HSA-8986944 refseq:NP_003101.3|ensembl:ENSG00000167182(gene)|ensembl:ENST00000376741(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006955"(immune response)|go:"GO:0035264"(multicellular organism growth)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0046872"(metal ion binding)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR030451|interpro:IPR036236|mint:Q02086|go:"GO:0006357"(regulation of transcription by RNA polymerase II) go:"GO:0005634"(nucleus) - comment:mint figure legend:ST2 F2A|comment:proteins identified only in our induced samples in three MudPIT analyses with the more stringent BY-adjusted significance p<0.05|dataset:Brain Disease - Neurological Diseases & Disorders|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-daoy)|taxid:9606(Homo sapiens DAOY cerebellar medulloblastoma cell line) - 2020/12/29 2020/12/29 rogid:cn8gYfKDpQc8J2ygnqny32sIyyU9606 rogid:qPArAxIAAhmVWRehLwGsX8w/FKA9606 rigid:6EMs5+B89Q89RCR/2S2BG6PhH9E false tandem tag:n-n - - - psi-mi:"MI:0658"(multidimensional protein identification technology) psi-mi:"MI:0658"(multidimensional protein identification technology) uniprotkb:P48431 uniprotkb:O15090 intact:EBI-6124081|uniprotkb:Q14537|ensembl:ENSP00000323588 intact:EBI-11317710|uniprotkb:A2RU18|ensembl:ENSP00000347730 psi-mi:sox2_human(display_long)|uniprotkb:SOX2(gene name)|psi-mi:SOX2(display_short) psi-mi:zn536_human(display_long)|uniprotkb:KIAA0390(gene name synonym)|uniprotkb:ZNF536(gene name)|psi-mi:ZNF536(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Cox et al. (2012) pubmed:23667531|imex:IM-28599 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-26574619|imex:IM-28599-5 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_003097.1|dip:DIP-59913N|ensembl:ENSG00000181449(gene)|ensembl:ENST00000325404(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001649"(osteoblast differentiation)|go:"GO:0001654"(eye development)|go:"GO:0001714"(endodermal cell fate specification)|go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006325"(chromatin organization)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0009611"(response to wounding)|go:"GO:0009653"(anatomical structure morphogenesis)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0021781"(glial cell fate commitment)|go:"GO:0021983"(pituitary gland development)|go:"GO:0021984"(adenohypophysis development)|go:"GO:0022409"(positive regulation of cell-cell adhesion)|go:"GO:0030154"(cell differentiation)|go:"GO:0030900"(forebrain development)|go:"GO:0035019"(somatic stem cell population maintenance)|go:"GO:0035198"(miRNA binding)|go:"GO:0042246"(tissue regeneration)|go:"GO:0043281"(regulation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0043410"(positive regulation of MAPK cascade)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045165"(cell fate commitment)|go:"GO:0045597"(positive regulation of cell differentiation)|go:"GO:0045665"(negative regulation of neuron differentiation)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048839"(inner ear development)|go:"GO:0050680"(negative regulation of epithelial cell proliferation)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0070848"(response to growth factor)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:0097150"(neuronal stem cell population maintenance)|interpro:IPR009071(High mobility group box, HMG)|interpro:IPR022097|interpro:IPR032643|interpro:IPR036910|mint:P48431|rcsb pdb:1O4X|rcsb pdb:2LE4|rcsb pdb:6T7B|rcsb pdb:6T90|rcsb pdb:6WX7|rcsb pdb:6WX8|rcsb pdb:6WX9|rcsb pdb:6YOV|reactome:R-HSA-2892245|reactome:R-HSA-2892247|reactome:R-HSA-3769402|reactome:R-HSA-452723|reactome:R-HSA-6785807|reactome:R-HSA-8986944 refseq:NP_055532.1|ensembl:ENSG00000198597(gene)|ensembl:ENST00000355537(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0005634"(nucleus)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0044323"(retinoic acid-responsive element binding)|go:"GO:0045665"(negative regulation of neuron differentiation)|go:"GO:0046872"(metal ion binding)|go:"GO:0048387"(negative regulation of retinoic acid receptor signaling pathway)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR036236|mint:O15090|refseq:XP_016883031.1 go:"GO:0005634"(nucleus) - - figure legend:ST2 F2A|comment:proteins identified only in our induced samples in three MudPIT analyses with the more stringent BY-adjusted significance p<0.05|dataset:Brain Disease - Neurological Diseases & Disorders|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-daoy)|taxid:9606(Homo sapiens DAOY cerebellar medulloblastoma cell line) - 2020/12/29 2020/12/29 rogid:cn8gYfKDpQc8J2ygnqny32sIyyU9606 rogid:kubnGIrin8zpGyKC2EDGeBI/yT89606 rigid:6EMs5+B89Q89RCR/2S2BG6PhH9E false tandem tag:n-n - - - psi-mi:"MI:0658"(multidimensional protein identification technology) psi-mi:"MI:0658"(multidimensional protein identification technology) uniprotkb:P48431 uniprotkb:Q9HD40 intact:EBI-6124081|uniprotkb:Q14537|ensembl:ENSP00000323588 intact:EBI-6163446|uniprotkb:A8K8W1|uniprotkb:Q0D2P3|uniprotkb:Q17RT1|uniprotkb:Q9NXZ5|uniprotkb:Q9UGM9|uniprotkb:Q9Y353|ensembl:ENSP00000371535 psi-mi:sox2_human(display_long)|uniprotkb:SOX2(gene name)|psi-mi:SOX2(display_short) psi-mi:spcs_human(display_long)|uniprotkb:SEPSECS(gene name)|psi-mi:SEPSECS(display_short)|uniprotkb:Liver-pancreas antigen(gene name synonym)|uniprotkb:SLA-p35(gene name synonym)|uniprotkb:SLA/LP autoantigen(gene name synonym)|uniprotkb:Selenocysteine synthase(gene name synonym)|uniprotkb:"Selenocysteinyl-tRNA(Sec) synthase"(gene name synonym)|uniprotkb:"Sep-tRNA:Sec-tRNA synthase"(gene name synonym)|uniprotkb:Soluble liver antigen(gene name synonym)|uniprotkb:TRNP48(gene name synonym)|uniprotkb:UGA suppressor tRNA-associated protein(gene name synonym)|uniprotkb:"tRNA(Ser/Sec)-associated antigenic protein"(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Cox et al. (2012) pubmed:23667531|imex:IM-28599 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-26574619|imex:IM-28599-5 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_003097.1|dip:DIP-59913N|ensembl:ENSG00000181449(gene)|ensembl:ENST00000325404(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001649"(osteoblast differentiation)|go:"GO:0001654"(eye development)|go:"GO:0001714"(endodermal cell fate specification)|go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006325"(chromatin organization)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0009611"(response to wounding)|go:"GO:0009653"(anatomical structure morphogenesis)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0021781"(glial cell fate commitment)|go:"GO:0021983"(pituitary gland development)|go:"GO:0021984"(adenohypophysis development)|go:"GO:0022409"(positive regulation of cell-cell adhesion)|go:"GO:0030154"(cell differentiation)|go:"GO:0030900"(forebrain development)|go:"GO:0035019"(somatic stem cell population maintenance)|go:"GO:0035198"(miRNA binding)|go:"GO:0042246"(tissue regeneration)|go:"GO:0043281"(regulation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0043410"(positive regulation of MAPK cascade)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045165"(cell fate commitment)|go:"GO:0045597"(positive regulation of cell differentiation)|go:"GO:0045665"(negative regulation of neuron differentiation)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048839"(inner ear development)|go:"GO:0050680"(negative regulation of epithelial cell proliferation)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0070848"(response to growth factor)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:0097150"(neuronal stem cell population maintenance)|interpro:IPR009071(High mobility group box, HMG)|interpro:IPR022097|interpro:IPR032643|interpro:IPR036910|mint:P48431|rcsb pdb:1O4X|rcsb pdb:2LE4|rcsb pdb:6T7B|rcsb pdb:6T90|rcsb pdb:6WX7|rcsb pdb:6WX8|rcsb pdb:6WX9|rcsb pdb:6YOV|reactome:R-HSA-2892245|reactome:R-HSA-2892247|reactome:R-HSA-3769402|reactome:R-HSA-452723|reactome:R-HSA-6785807|reactome:R-HSA-8986944 refseq:XP_011512148.1|refseq:XP_011512150.1|refseq:NP_058651.3|ensembl:ENSG00000109618(gene)|ensembl:ENST00000382103(transcript)|go:"GO:0000049"(tRNA binding)|go:"GO:0001514"(selenocysteine incorporation)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0097056"("selenocysteinyl-tRNA(Sec) biosynthetic process")|go:"GO:0098621"(phosphoseryl-selenocysteinyl-tRNA selenium transferase activity)|interpro:IPR008829(Soluble liver antigen/liver pancreas antigen)|interpro:IPR015421(Pyridoxal phosphate-dependent transferase, major region, subdomain 1)|interpro:IPR015424(Pyridoxal phosphate-dependent transferase, major region)|interpro:IPR019793|interpro:IPR019872|mint:Q9HD40|rcsb pdb:3HL2|rcsb pdb:4ZDL|rcsb pdb:4ZDO|rcsb pdb:4ZDP|reactome:R-HSA-2408557 go:"GO:0005634"(nucleus) - - figure legend:ST2 F2A|comment:proteins identified only in our induced samples in three MudPIT analyses with the more stringent BY-adjusted significance p<0.05|dataset:Brain Disease - Neurological Diseases & Disorders|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-daoy)|taxid:9606(Homo sapiens DAOY cerebellar medulloblastoma cell line) - 2020/12/29 2020/12/29 rogid:cn8gYfKDpQc8J2ygnqny32sIyyU9606 rogid:1xxyUK7bIUrg8CrosJ+/gdX8nXw9606 rigid:6EMs5+B89Q89RCR/2S2BG6PhH9E false tandem tag:n-n - - - psi-mi:"MI:0658"(multidimensional protein identification technology) psi-mi:"MI:0658"(multidimensional protein identification technology) uniprotkb:P48431 uniprotkb:Q9H0H0 intact:EBI-6124081|uniprotkb:Q14537|ensembl:ENSP00000323588 intact:EBI-8471507|uniprotkb:Q9ULD3|intact:MINT-4712719|ensembl:ENSP00000414237|ensembl:ENSP00000482710 psi-mi:sox2_human(display_long)|uniprotkb:SOX2(gene name)|psi-mi:SOX2(display_short) psi-mi:int2_human(display_long)|uniprotkb:INTS2(gene name)|psi-mi:INTS2(display_short)|uniprotkb:KIAA1287(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Cox et al. (2012) pubmed:23667531|imex:IM-28599 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-26574619|imex:IM-28599-5 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_003097.1|dip:DIP-59913N|ensembl:ENSG00000181449(gene)|ensembl:ENST00000325404(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001649"(osteoblast differentiation)|go:"GO:0001654"(eye development)|go:"GO:0001714"(endodermal cell fate specification)|go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006325"(chromatin organization)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0009611"(response to wounding)|go:"GO:0009653"(anatomical structure morphogenesis)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0021781"(glial cell fate commitment)|go:"GO:0021983"(pituitary gland development)|go:"GO:0021984"(adenohypophysis development)|go:"GO:0022409"(positive regulation of cell-cell adhesion)|go:"GO:0030154"(cell differentiation)|go:"GO:0030900"(forebrain development)|go:"GO:0035019"(somatic stem cell population maintenance)|go:"GO:0035198"(miRNA binding)|go:"GO:0042246"(tissue regeneration)|go:"GO:0043281"(regulation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0043410"(positive regulation of MAPK cascade)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045165"(cell fate commitment)|go:"GO:0045597"(positive regulation of cell differentiation)|go:"GO:0045665"(negative regulation of neuron differentiation)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048839"(inner ear development)|go:"GO:0050680"(negative regulation of epithelial cell proliferation)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0070848"(response to growth factor)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:0097150"(neuronal stem cell population maintenance)|interpro:IPR009071(High mobility group box, HMG)|interpro:IPR022097|interpro:IPR032643|interpro:IPR036910|mint:P48431|rcsb pdb:1O4X|rcsb pdb:2LE4|rcsb pdb:6T7B|rcsb pdb:6T90|rcsb pdb:6WX7|rcsb pdb:6WX8|rcsb pdb:6WX9|rcsb pdb:6YOV|reactome:R-HSA-2892245|reactome:R-HSA-2892247|reactome:R-HSA-3769402|reactome:R-HSA-452723|reactome:R-HSA-6785807|reactome:R-HSA-8986944 refseq:NP_001317346.1|dip:DIP-48477N|refseq:NP_065799.1|ensembl:ENSG00000108506(gene)|ensembl:ENST00000444766(transcript)|ensembl:ENST00000617492(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0031965"(nuclear membrane)|go:"GO:0032039"(integrator complex)|go:"GO:0034472"(snRNA 3'-end processing)|interpro:IPR026236|interpro:IPR029321|mint:Q9H0H0|rcsb pdb:7CUN|reactome:R-HSA-6807505|go:"GO:0016180"(snRNA processing) go:"GO:0005634"(nucleus) - function:"Component of the Integrator complex, a complex involved in the small nuclear RNAs (snRNA) U1 and U2 transcription and in their 3'-box-dependent processing. The Integrator complex is associated with the C-terminal domain (CTD) of RNA polymerase II largest subunit (POLR2A) and is recruited to the U1 and U2 snRNAs genes"|comment:mint|comment:homomint figure legend:ST2 F2A|comment:proteins identified only in our induced samples in three MudPIT analyses with the more stringent BY-adjusted significance p<0.05|dataset:Brain Disease - Neurological Diseases & Disorders|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-daoy)|taxid:9606(Homo sapiens DAOY cerebellar medulloblastoma cell line) - 2020/12/29 2020/12/29 rogid:cn8gYfKDpQc8J2ygnqny32sIyyU9606 rogid:kbczUMPyLBZtWLKxKPd5DHI35zc9606 rigid:6EMs5+B89Q89RCR/2S2BG6PhH9E false tandem tag:n-n - - - psi-mi:"MI:0658"(multidimensional protein identification technology) psi-mi:"MI:0658"(multidimensional protein identification technology) uniprotkb:P48431 uniprotkb:P55081 intact:EBI-6124081|uniprotkb:Q14537|ensembl:ENSP00000323588 intact:EBI-1048159|uniprotkb:Q86TG6|ensembl:ENSP00000267812 psi-mi:sox2_human(display_long)|uniprotkb:SOX2(gene name)|psi-mi:SOX2(display_short) psi-mi:mfap1_human(display_long)|uniprotkb:Spliceosome B complex protein MFAP1(gene name synonym)|uniprotkb:MFAP1(gene name)|psi-mi:MFAP1(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Cox et al. (2012) pubmed:23667531|imex:IM-28599 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-26574619|imex:IM-28599-5 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_003097.1|dip:DIP-59913N|ensembl:ENSG00000181449(gene)|ensembl:ENST00000325404(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001649"(osteoblast differentiation)|go:"GO:0001654"(eye development)|go:"GO:0001714"(endodermal cell fate specification)|go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006325"(chromatin organization)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0009611"(response to wounding)|go:"GO:0009653"(anatomical structure morphogenesis)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0021781"(glial cell fate commitment)|go:"GO:0021983"(pituitary gland development)|go:"GO:0021984"(adenohypophysis development)|go:"GO:0022409"(positive regulation of cell-cell adhesion)|go:"GO:0030154"(cell differentiation)|go:"GO:0030900"(forebrain development)|go:"GO:0035019"(somatic stem cell population maintenance)|go:"GO:0035198"(miRNA binding)|go:"GO:0042246"(tissue regeneration)|go:"GO:0043281"(regulation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0043410"(positive regulation of MAPK cascade)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045165"(cell fate commitment)|go:"GO:0045597"(positive regulation of cell differentiation)|go:"GO:0045665"(negative regulation of neuron differentiation)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048839"(inner ear development)|go:"GO:0050680"(negative regulation of epithelial cell proliferation)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0070848"(response to growth factor)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:0097150"(neuronal stem cell population maintenance)|interpro:IPR009071(High mobility group box, HMG)|interpro:IPR022097|interpro:IPR032643|interpro:IPR036910|mint:P48431|rcsb pdb:1O4X|rcsb pdb:2LE4|rcsb pdb:6T7B|rcsb pdb:6T90|rcsb pdb:6WX7|rcsb pdb:6WX8|rcsb pdb:6WX9|rcsb pdb:6YOV|reactome:R-HSA-2892245|reactome:R-HSA-2892247|reactome:R-HSA-3769402|reactome:R-HSA-452723|reactome:R-HSA-6785807|reactome:R-HSA-8986944 refseq:NP_005917.2|ensembl:ENSG00000140259(gene)|ensembl:ENST00000267812(transcript)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0001527"(microfibril)|go:"GO:0003723"(RNA binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005684"(U2-type spliceosomal complex)|go:"GO:0005813"(centrosome)|go:"GO:0071005"(U2-type precatalytic spliceosome)|interpro:IPR009730(Micro-fibrillar-associated 1, C-terminal)|interpro:IPR033194|mint:P55081|rcsb pdb:5F5S|rcsb pdb:5O9Z|rcsb pdb:6AHD|rcsb pdb:7AAV|rcsb pdb:7ABF|rcsb pdb:7ABG|rcsb pdb:7ABI|reactome:R-HSA-2129379 go:"GO:0005634"(nucleus) - - figure legend:ST2 F2A|comment:proteins identified only in our induced samples in three MudPIT analyses with the more stringent BY-adjusted significance p<0.05|dataset:Brain Disease - Neurological Diseases & Disorders|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-daoy)|taxid:9606(Homo sapiens DAOY cerebellar medulloblastoma cell line) - 2020/12/29 2020/12/29 rogid:cn8gYfKDpQc8J2ygnqny32sIyyU9606 rogid:38SGUW2hc2ZwbmyTO52uGQRw79U9606 rigid:6EMs5+B89Q89RCR/2S2BG6PhH9E false tandem tag:n-n - - - psi-mi:"MI:0658"(multidimensional protein identification technology) psi-mi:"MI:0658"(multidimensional protein identification technology) uniprotkb:P48431 uniprotkb:Q8WVM8 intact:EBI-6124081|uniprotkb:Q14537|ensembl:ENSP00000323588 intact:EBI-722569|uniprotkb:O60754|uniprotkb:O94990|uniprotkb:Q7Z529|uniprotkb:Q9BZI3|uniprotkb:Q9UNL3|uniprotkb:Q9Y6A8|uniprotkb:A8K2Z5|uniprotkb:B7Z4U7|uniprotkb:B7Z594|ensembl:ENSP00000390783 psi-mi:sox2_human(display_long)|uniprotkb:SOX2(gene name)|psi-mi:SOX2(display_short) psi-mi:scfd1_human(display_long)|uniprotkb:Syntaxin-binding protein 1-like 2(gene name synonym)|uniprotkb:SLY1 homolog(gene name synonym)|uniprotkb:FKSG23(orf name)|uniprotkb:SCFD1(gene name)|psi-mi:SCFD1(display_short)|uniprotkb:KIAA0917(gene name synonym)|uniprotkb:STXBP1L2(gene name synonym)|uniprotkb:C14orf163(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Cox et al. (2012) pubmed:23667531|imex:IM-28599 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-26574619|imex:IM-28599-5 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_003097.1|dip:DIP-59913N|ensembl:ENSG00000181449(gene)|ensembl:ENST00000325404(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001649"(osteoblast differentiation)|go:"GO:0001654"(eye development)|go:"GO:0001714"(endodermal cell fate specification)|go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006325"(chromatin organization)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0009611"(response to wounding)|go:"GO:0009653"(anatomical structure morphogenesis)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0021781"(glial cell fate commitment)|go:"GO:0021983"(pituitary gland development)|go:"GO:0021984"(adenohypophysis development)|go:"GO:0022409"(positive regulation of cell-cell adhesion)|go:"GO:0030154"(cell differentiation)|go:"GO:0030900"(forebrain development)|go:"GO:0035019"(somatic stem cell population maintenance)|go:"GO:0035198"(miRNA binding)|go:"GO:0042246"(tissue regeneration)|go:"GO:0043281"(regulation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0043410"(positive regulation of MAPK cascade)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045165"(cell fate commitment)|go:"GO:0045597"(positive regulation of cell differentiation)|go:"GO:0045665"(negative regulation of neuron differentiation)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048839"(inner ear development)|go:"GO:0050680"(negative regulation of epithelial cell proliferation)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0070848"(response to growth factor)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:0097150"(neuronal stem cell population maintenance)|interpro:IPR009071(High mobility group box, HMG)|interpro:IPR022097|interpro:IPR032643|interpro:IPR036910|mint:P48431|rcsb pdb:1O4X|rcsb pdb:2LE4|rcsb pdb:6T7B|rcsb pdb:6T90|rcsb pdb:6WX7|rcsb pdb:6WX8|rcsb pdb:6WX9|rcsb pdb:6YOV|reactome:R-HSA-2892245|reactome:R-HSA-2892247|reactome:R-HSA-3769402|reactome:R-HSA-452723|reactome:R-HSA-6785807|reactome:R-HSA-8986944 refseq:NP_001269961.1|refseq:NP_057190.2|refseq:NP_001244305.1|refseq:NP_878255.1|mint:Q8WVM8|reactome:R-HSA-204005|reactome:R-HSA-8980692|ensembl:ENSG00000092108(gene)|ensembl:ENST00000458591(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0000902"(cell morphogenesis)|go:"GO:0001666"(response to hypoxia)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005798"(Golgi-associated vesicle)|go:"GO:0005801"(cis-Golgi network)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0006890"(retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum)|go:"GO:0006892"(post-Golgi vesicle-mediated transport)|go:"GO:0009636"(response to toxic substance)|go:"GO:0016192"(vesicle-mediated transport)|go:"GO:0019905"(syntaxin binding)|go:"GO:0032580"(Golgi cisterna membrane)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0047485"(protein N-terminus binding)|go:"GO:0051223"(regulation of protein transport)|go:"GO:0060628"(regulation of ER to Golgi vesicle-mediated transport)|go:"GO:1901998"(toxin transport)|go:"GO:1902902"(negative regulation of autophagosome assembly)|interpro:IPR001619(Sec1-like protein)|interpro:IPR027482|interpro:IPR036045|interpro:IPR043127|interpro:IPR043154 go:"GO:0005634"(nucleus) - - figure legend:ST2 F2A|comment:proteins identified only in our induced samples in three MudPIT analyses with the more stringent BY-adjusted significance p<0.05|dataset:Brain Disease - Neurological Diseases & Disorders|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-daoy)|taxid:9606(Homo sapiens DAOY cerebellar medulloblastoma cell line) - 2020/12/29 2020/12/29 rogid:cn8gYfKDpQc8J2ygnqny32sIyyU9606 rogid:7cD2Z6zhuKLCd3ERB+pVNRdVexY9606 rigid:6EMs5+B89Q89RCR/2S2BG6PhH9E false tandem tag:n-n - - - psi-mi:"MI:0658"(multidimensional protein identification technology) psi-mi:"MI:0658"(multidimensional protein identification technology) uniprotkb:P48431 uniprotkb:O75175 intact:EBI-6124081|uniprotkb:Q14537|ensembl:ENSP00000323588 intact:EBI-743073|ensembl:ENSP00000221232|ensembl:ENSP00000351159|ensembl:ENSP00000478280|ensembl:ENSP00000478956|ensembl:ENSP00000479987|ensembl:ENSP00000480258|ensembl:ENSP00000480585|ensembl:ENSP00000480697|ensembl:ENSP00000480876|ensembl:ENSP00000480988|ensembl:ENSP00000481681|ensembl:ENSP00000481924|ensembl:ENSP00000483036|ensembl:ENSP00000483431|ensembl:ENSP00000483604|ensembl:ENSP00000483692|ensembl:ENSP00000483882|ensembl:ENSP00000483968|ensembl:ENSP00000484040|ensembl:ENSP00000484794|uniprotkb:Q9NZN7|uniprotkb:Q9UF76|intact:EBI-6504867 psi-mi:sox2_human(display_long)|uniprotkb:SOX2(gene name)|psi-mi:SOX2(display_short) psi-mi:cnot3_human(display_long)|uniprotkb:CCR4-associated factor 3(gene name synonym)|uniprotkb:Leukocyte receptor cluster member 2(gene name synonym)|uniprotkb:CNOT3(gene name)|psi-mi:CNOT3(display_short)|uniprotkb:KIAA0691(gene name synonym)|uniprotkb:NOT3(gene name synonym)|uniprotkb:LENG2(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Cox et al. (2012) pubmed:23667531|imex:IM-28599 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-26574619|imex:IM-28599-5 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_003097.1|dip:DIP-59913N|ensembl:ENSG00000181449(gene)|ensembl:ENST00000325404(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001649"(osteoblast differentiation)|go:"GO:0001654"(eye development)|go:"GO:0001714"(endodermal cell fate specification)|go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006325"(chromatin organization)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0009611"(response to wounding)|go:"GO:0009653"(anatomical structure morphogenesis)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0021781"(glial cell fate commitment)|go:"GO:0021983"(pituitary gland development)|go:"GO:0021984"(adenohypophysis development)|go:"GO:0022409"(positive regulation of cell-cell adhesion)|go:"GO:0030154"(cell differentiation)|go:"GO:0030900"(forebrain development)|go:"GO:0035019"(somatic stem cell population maintenance)|go:"GO:0035198"(miRNA binding)|go:"GO:0042246"(tissue regeneration)|go:"GO:0043281"(regulation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0043410"(positive regulation of MAPK cascade)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045165"(cell fate commitment)|go:"GO:0045597"(positive regulation of cell differentiation)|go:"GO:0045665"(negative regulation of neuron differentiation)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048839"(inner ear development)|go:"GO:0050680"(negative regulation of epithelial cell proliferation)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0070848"(response to growth factor)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:0097150"(neuronal stem cell population maintenance)|interpro:IPR009071(High mobility group box, HMG)|interpro:IPR022097|interpro:IPR032643|interpro:IPR036910|mint:P48431|rcsb pdb:1O4X|rcsb pdb:2LE4|rcsb pdb:6T7B|rcsb pdb:6T90|rcsb pdb:6WX7|rcsb pdb:6WX8|rcsb pdb:6WX9|rcsb pdb:6YOV|reactome:R-HSA-2892245|reactome:R-HSA-2892247|reactome:R-HSA-3769402|reactome:R-HSA-452723|reactome:R-HSA-6785807|reactome:R-HSA-8986944 ensembl:ENSG00000088038(gene)|ensembl:ENSG00000273943(gene)|ensembl:ENSG00000274176(gene)|ensembl:ENSG00000274616(gene)|ensembl:ENSG00000274941(gene)|ensembl:ENSG00000275979(gene)|ensembl:ENSG00000276082(gene)|ensembl:ENSG00000277114(gene)|ensembl:ENSG00000277600(gene)|ensembl:ENSG00000277615(gene)|ensembl:ENST00000221232(transcript)|ensembl:ENST00000358389(transcript)|ensembl:ENST00000610883(transcript)|ensembl:ENST00000611252(transcript)|ensembl:ENST00000612924(transcript)|ensembl:ENST00000613528(transcript)|ensembl:ENST00000613752(transcript)|ensembl:ENST00000614649(transcript)|ensembl:ENST00000615030(transcript)|ensembl:ENST00000616359(transcript)|ensembl:ENST00000616910(transcript)|ensembl:ENST00000617982(transcript)|ensembl:ENST00000618405(transcript)|ensembl:ENST00000619567(transcript)|ensembl:ENST00000619854(transcript)|ensembl:ENST00000620060(transcript)|ensembl:ENST00000620419(transcript)|ensembl:ENST00000620573(transcript)|ensembl:ENST00000620970(transcript)|ensembl:ENST00000622131(transcript)|go:"GO:0000289"("nuclear-transcribed mRNA poly(A) tail shortening")|go:"GO:0000932"(P-body)|go:"GO:0001829"(trophectodermal cell differentiation)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0030014"(CCR4-NOT complex)|go:"GO:0030015"(CCR4-NOT core complex)|go:"GO:0031047"(gene silencing by RNA)|go:"GO:0120162"(positive regulation of cold-induced thermogenesis)|go:"GO:2000036"(regulation of stem cell population maintenance)|interpro:IPR007207(Not CCR4-Not complex component, N-terminal)|interpro:IPR007282(NOT2/NOT3/NOT5)|interpro:IPR012270(CCR4-NOT complex, subunits 3 and 5)|interpro:IPR038635|interpro:IPR040168|mint:O75175|rcsb pdb:4C0D|rcsb pdb:4C0G|rcsb pdb:5FU6|rcsb pdb:5FU7|reactome:R-HSA-429947|reactome:R-HSA-6804115|refseq:NP_055331.1|dip:DIP-40297N go:"GO:0005634"(nucleus) - - figure legend:ST2 F2A|comment:proteins identified only in our induced samples in three MudPIT analyses with the more stringent BY-adjusted significance p<0.05|dataset:Brain Disease - Neurological Diseases & Disorders|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-daoy)|taxid:9606(Homo sapiens DAOY cerebellar medulloblastoma cell line) - 2020/12/29 2020/12/29 rogid:cn8gYfKDpQc8J2ygnqny32sIyyU9606 rogid:Qm4YvclCLIfpgmygrSHtkxn/H9E9606 rigid:6EMs5+B89Q89RCR/2S2BG6PhH9E false tandem tag:n-n - - - psi-mi:"MI:0658"(multidimensional protein identification technology) psi-mi:"MI:0658"(multidimensional protein identification technology) uniprotkb:P48431 uniprotkb:Q12929 intact:EBI-6124081|uniprotkb:Q14537|ensembl:ENSP00000323588 intact:EBI-375576|uniprotkb:A6NMC3|ensembl:ENSP00000281172|ensembl:ENSP00000441867|ensembl:ENSP00000442388|ensembl:ENSP00000494689|ensembl:ENSP00000494842|ensembl:ENSP00000495722|ensembl:ENSP00000495824|ensembl:ENSP00000495956|ensembl:ENSP00000496406|ensembl:ENSP00000496516|uniprotkb:Q8N6J0|uniprotkb:B4DX66|uniprotkb:A8K6W2|uniprotkb:A8KA66 psi-mi:sox2_human(display_long)|uniprotkb:SOX2(gene name)|psi-mi:SOX2(display_short) psi-mi:eps8_human(display_long)|uniprotkb:EPS8(gene name)|psi-mi:EPS8(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Cox et al. (2012) pubmed:23667531|imex:IM-28599 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-26574619|imex:IM-28599-5 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_003097.1|dip:DIP-59913N|ensembl:ENSG00000181449(gene)|ensembl:ENST00000325404(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001649"(osteoblast differentiation)|go:"GO:0001654"(eye development)|go:"GO:0001714"(endodermal cell fate specification)|go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006325"(chromatin organization)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0009611"(response to wounding)|go:"GO:0009653"(anatomical structure morphogenesis)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0021781"(glial cell fate commitment)|go:"GO:0021983"(pituitary gland development)|go:"GO:0021984"(adenohypophysis development)|go:"GO:0022409"(positive regulation of cell-cell adhesion)|go:"GO:0030154"(cell differentiation)|go:"GO:0030900"(forebrain development)|go:"GO:0035019"(somatic stem cell population maintenance)|go:"GO:0035198"(miRNA binding)|go:"GO:0042246"(tissue regeneration)|go:"GO:0043281"(regulation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0043410"(positive regulation of MAPK cascade)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045165"(cell fate commitment)|go:"GO:0045597"(positive regulation of cell differentiation)|go:"GO:0045665"(negative regulation of neuron differentiation)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048839"(inner ear development)|go:"GO:0050680"(negative regulation of epithelial cell proliferation)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0070848"(response to growth factor)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:0097150"(neuronal stem cell population maintenance)|interpro:IPR009071(High mobility group box, HMG)|interpro:IPR022097|interpro:IPR032643|interpro:IPR036910|mint:P48431|rcsb pdb:1O4X|rcsb pdb:2LE4|rcsb pdb:6T7B|rcsb pdb:6T90|rcsb pdb:6WX7|rcsb pdb:6WX8|rcsb pdb:6WX9|rcsb pdb:6YOV|reactome:R-HSA-2892245|reactome:R-HSA-2892247|reactome:R-HSA-3769402|reactome:R-HSA-452723|reactome:R-HSA-6785807|reactome:R-HSA-8986944 ensembl:ENST00000645775(transcript)|ensembl:ENST00000646828(transcript)|ensembl:ENSG00000151491(gene)|ensembl:ENST00000646918(transcript)|ensembl:ENST00000647087(transcript)|ensembl:ENST00000647224(transcript)|go:"GO:0003779"(actin binding)|go:"GO:0005886"(plasma membrane)|go:"GO:0005903"(brush border)|go:"GO:0005938"(cell cortex)|go:"GO:0007266"(Rho protein signal transduction)|go:"GO:0008344"(adult locomotory behavior)|go:"GO:0008360"(regulation of cell shape)|go:"GO:0010458"(exit from mitosis)|go:"GO:0014069"(postsynaptic density)|go:"GO:0016601"(Rac protein signal transduction)|go:"GO:0017146"(NMDA selective glutamate receptor complex)|go:"GO:0030426"(growth cone)|go:"GO:0030832"(regulation of actin filament length)|go:"GO:0031267"(small GTPase binding)|ensembl:ENST00000281172(transcript)|ensembl:ENST00000543523(transcript)|go:"GO:0031532"(actin cytoskeleton reorganization)|go:"GO:0031982"(vesicle)|go:"GO:0032420"(stereocilium)|go:"GO:0032426"(stereocilium tip)|ensembl:ENST00000543612(transcript)|ensembl:ENST00000642278(transcript)|ensembl:ENST00000644374(transcript)|go:"GO:0032587"(ruffle membrane)|go:"GO:0035023"(regulation of Rho protein signal transduction)|go:"GO:0035591"(signaling adaptor activity)|go:"GO:0036336"(dendritic cell migration)|go:"GO:0048149"(behavioral response to ethanol)|go:"GO:0051016"(barbed-end actin filament capping)|go:"GO:0051017"(actin filament bundle assembly)|go:"GO:0051764"(actin crosslink formation)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070358"(actin polymerization-dependent cell motility)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099072"(regulation of postsynaptic membrane neurotransmitter receptor levels)|go:"GO:1900029"(positive regulation of ruffle assembly)|go:"GO:1990830"(cellular response to leukemia inhibitory factor)|interpro:IPR001452(Src homology-3)|interpro:IPR006020(Phosphotyrosine interaction region)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR013625(Tensin phosphotyrosine-binding domain)|interpro:IPR013761(Sterile alpha motif-type)|interpro:IPR030222|interpro:IPR033928|interpro:IPR035462|interpro:IPR036028|interpro:IPR039801|interpro:IPR041418|mint:Q12929|rcsb pdb:2E8M|reactome:R-HSA-9662360|reactome:R-HSA-9662361|refseq:NP_004438.3|dip:DIP-32859N go:"GO:0005634"(nucleus) - - figure legend:ST2 F2A|comment:proteins identified only in our induced samples in three MudPIT analyses with the more stringent BY-adjusted significance p<0.05|dataset:Brain Disease - Neurological Diseases & Disorders|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-daoy)|taxid:9606(Homo sapiens DAOY cerebellar medulloblastoma cell line) - 2020/12/29 2020/12/29 rogid:cn8gYfKDpQc8J2ygnqny32sIyyU9606 rogid:ulBgb+4uZ7XrN4bLogRtd9I5AbY9606 rigid:6EMs5+B89Q89RCR/2S2BG6PhH9E false tandem tag:n-n - - - psi-mi:"MI:0658"(multidimensional protein identification technology) psi-mi:"MI:0658"(multidimensional protein identification technology) uniprotkb:P48431 uniprotkb:Q9BYD2 intact:EBI-6124081|uniprotkb:Q14537|ensembl:ENSP00000323588 intact:EBI-726059|uniprotkb:Q9BSW8|uniprotkb:Q5SZR2|uniprotkb:B2RD99|ensembl:ENSP00000357823 psi-mi:sox2_human(display_long)|uniprotkb:SOX2(gene name)|psi-mi:SOX2(display_short) psi-mi:rm09_human(display_long)|uniprotkb:MRPL9(gene name)|psi-mi:MRPL9(display_short)|uniprotkb:Mitochondrial large ribosomal subunit protein bL9m(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Cox et al. (2012) pubmed:23667531|imex:IM-28599 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-26574619|imex:IM-28599-5 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_003097.1|dip:DIP-59913N|ensembl:ENSG00000181449(gene)|ensembl:ENST00000325404(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001649"(osteoblast differentiation)|go:"GO:0001654"(eye development)|go:"GO:0001714"(endodermal cell fate specification)|go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006325"(chromatin organization)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0009611"(response to wounding)|go:"GO:0009653"(anatomical structure morphogenesis)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0021781"(glial cell fate commitment)|go:"GO:0021983"(pituitary gland development)|go:"GO:0021984"(adenohypophysis development)|go:"GO:0022409"(positive regulation of cell-cell adhesion)|go:"GO:0030154"(cell differentiation)|go:"GO:0030900"(forebrain development)|go:"GO:0035019"(somatic stem cell population maintenance)|go:"GO:0035198"(miRNA binding)|go:"GO:0042246"(tissue regeneration)|go:"GO:0043281"(regulation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0043410"(positive regulation of MAPK cascade)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045165"(cell fate commitment)|go:"GO:0045597"(positive regulation of cell differentiation)|go:"GO:0045665"(negative regulation of neuron differentiation)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048839"(inner ear development)|go:"GO:0050680"(negative regulation of epithelial cell proliferation)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0070848"(response to growth factor)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:0097150"(neuronal stem cell population maintenance)|interpro:IPR009071(High mobility group box, HMG)|interpro:IPR022097|interpro:IPR032643|interpro:IPR036910|mint:P48431|rcsb pdb:1O4X|rcsb pdb:2LE4|rcsb pdb:6T7B|rcsb pdb:6T90|rcsb pdb:6WX7|rcsb pdb:6WX8|rcsb pdb:6WX9|rcsb pdb:6YOV|reactome:R-HSA-2892245|reactome:R-HSA-2892247|reactome:R-HSA-3769402|reactome:R-HSA-452723|reactome:R-HSA-6785807|reactome:R-HSA-8986944 refseq:NP_113608.1|refseq:NP_001287662.1|ensembl:ENSG00000143436(gene)|ensembl:ENST00000368830(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005761"(mitochondrial ribosome)|go:"GO:0005762"(mitochondrial large ribosomal subunit)|go:"GO:0006412"(translation)|interpro:IPR000244(Ribosomal protein L9)|interpro:IPR009027(Ribosomal protein L9 N-terminal-like)|interpro:IPR020070|interpro:IPR036935|mint:Q9BYD2|rcsb pdb:3J7Y|rcsb pdb:3J9M|rcsb pdb:5OOL|rcsb pdb:5OOM|rcsb pdb:6I9R|rcsb pdb:6NU2|rcsb pdb:6NU3|rcsb pdb:6VLZ|rcsb pdb:6VMI|rcsb pdb:6ZM5|rcsb pdb:6ZM6|rcsb pdb:6ZS9|rcsb pdb:6ZSA|rcsb pdb:6ZSB|rcsb pdb:6ZSC|rcsb pdb:6ZSD|rcsb pdb:6ZSE|rcsb pdb:6ZSG|rcsb pdb:7A5F|rcsb pdb:7A5G|rcsb pdb:7A5H|rcsb pdb:7A5I|rcsb pdb:7A5J|rcsb pdb:7A5K|rcsb pdb:7L08|rcsb pdb:7L20|rcsb pdb:7O9K|rcsb pdb:7O9M|rcsb pdb:7ODR|rcsb pdb:7ODS|rcsb pdb:7ODT|rcsb pdb:7OF0|rcsb pdb:7OF2|rcsb pdb:7OF3|rcsb pdb:7OF4|rcsb pdb:7OF5|rcsb pdb:7OF6|rcsb pdb:7OF7|rcsb pdb:7OG4|reactome:R-HSA-5368286|reactome:R-HSA-5389840|reactome:R-HSA-5419276 go:"GO:0005634"(nucleus) - - figure legend:ST2 F2A|comment:proteins identified only in our induced samples in three MudPIT analyses with the more stringent BY-adjusted significance p<0.05|dataset:Brain Disease - Neurological Diseases & Disorders|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-daoy)|taxid:9606(Homo sapiens DAOY cerebellar medulloblastoma cell line) - 2020/12/29 2020/12/29 rogid:cn8gYfKDpQc8J2ygnqny32sIyyU9606 rogid:JeHxoAdUc13d+0EnTCGBAa9rlVc9606 rigid:6EMs5+B89Q89RCR/2S2BG6PhH9E false tandem tag:n-n - - - psi-mi:"MI:0658"(multidimensional protein identification technology) psi-mi:"MI:0658"(multidimensional protein identification technology) uniprotkb:P48431 uniprotkb:Q9UNS2 intact:EBI-6124081|uniprotkb:Q14537|ensembl:ENSP00000323588 intact:EBI-350590|uniprotkb:O43191|uniprotkb:Q7LDR6|uniprotkb:B2R683|ensembl:ENSP00000268717|uniprotkb:B4DY81 psi-mi:sox2_human(display_long)|uniprotkb:SOX2(gene name)|psi-mi:SOX2(display_short) psi-mi:csn3_human(display_long)|uniprotkb:COPS3(gene name)|psi-mi:COPS3(display_short)|uniprotkb:CSN3(gene name synonym)|uniprotkb:JAB1-containing signalosome subunit 3(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Cox et al. (2012) pubmed:23667531|imex:IM-28599 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-26574619|imex:IM-28599-5 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_003097.1|dip:DIP-59913N|ensembl:ENSG00000181449(gene)|ensembl:ENST00000325404(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001649"(osteoblast differentiation)|go:"GO:0001654"(eye development)|go:"GO:0001714"(endodermal cell fate specification)|go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006325"(chromatin organization)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0009611"(response to wounding)|go:"GO:0009653"(anatomical structure morphogenesis)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0021781"(glial cell fate commitment)|go:"GO:0021983"(pituitary gland development)|go:"GO:0021984"(adenohypophysis development)|go:"GO:0022409"(positive regulation of cell-cell adhesion)|go:"GO:0030154"(cell differentiation)|go:"GO:0030900"(forebrain development)|go:"GO:0035019"(somatic stem cell population maintenance)|go:"GO:0035198"(miRNA binding)|go:"GO:0042246"(tissue regeneration)|go:"GO:0043281"(regulation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0043410"(positive regulation of MAPK cascade)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045165"(cell fate commitment)|go:"GO:0045597"(positive regulation of cell differentiation)|go:"GO:0045665"(negative regulation of neuron differentiation)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048839"(inner ear development)|go:"GO:0050680"(negative regulation of epithelial cell proliferation)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0070848"(response to growth factor)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:0097150"(neuronal stem cell population maintenance)|interpro:IPR009071(High mobility group box, HMG)|interpro:IPR022097|interpro:IPR032643|interpro:IPR036910|mint:P48431|rcsb pdb:1O4X|rcsb pdb:2LE4|rcsb pdb:6T7B|rcsb pdb:6T90|rcsb pdb:6WX7|rcsb pdb:6WX8|rcsb pdb:6WX9|rcsb pdb:6YOV|reactome:R-HSA-2892245|reactome:R-HSA-2892247|reactome:R-HSA-3769402|reactome:R-HSA-452723|reactome:R-HSA-6785807|reactome:R-HSA-8986944 refseq:NP_001186054.1|refseq:NP_003644.2|ensembl:ENSG00000141030(gene)|ensembl:ENST00000268717(transcript)|go:"GO:0000338"(protein deneddylation)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0007165"(signal transduction)|go:"GO:0008180"(COP9 signalosome)|go:"GO:0009416"(response to light stimulus)|interpro:IPR000717(Proteasome component region PCI)|interpro:IPR036390|interpro:IPR037753|mint:Q9UNS2|rcsb pdb:4D10|rcsb pdb:4D18|rcsb pdb:4WSN|rcsb pdb:6R7F|rcsb pdb:6R7H|rcsb pdb:6R7I|rcsb pdb:6R7N|reactome:R-HSA-5696394|reactome:R-HSA-6781823|reactome:R-HSA-8856825|reactome:R-HSA-8951664|rcsb pdb:6R6H|refseq:NP_001303283.1|refseq:NP_001303284.1|refseq:NP_001303285.1|refseq:NP_001303286.1|refseq:NP_001303287.1|refseq:XP_005256894.1|dip:DIP-32478N go:"GO:0005634"(nucleus) - - figure legend:ST2 F2A|comment:proteins identified only in our induced samples in three MudPIT analyses with the more stringent BY-adjusted significance p<0.05|dataset:Brain Disease - Neurological Diseases & Disorders|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-daoy)|taxid:9606(Homo sapiens DAOY cerebellar medulloblastoma cell line) - 2020/12/29 2020/12/29 rogid:cn8gYfKDpQc8J2ygnqny32sIyyU9606 rogid:z6E/tPEo/ksVxD5Yyfo89t+ww989606 rigid:6EMs5+B89Q89RCR/2S2BG6PhH9E false tandem tag:n-n - - - psi-mi:"MI:0658"(multidimensional protein identification technology) psi-mi:"MI:0658"(multidimensional protein identification technology) uniprotkb:P48431 uniprotkb:Q01196 intact:EBI-6124081|uniprotkb:Q14537|ensembl:ENSP00000323588 intact:EBI-925904|uniprotkb:O60472|uniprotkb:O60473|uniprotkb:O76047|uniprotkb:O76089|uniprotkb:Q13081|uniprotkb:Q13755|uniprotkb:Q13756|uniprotkb:Q13757|uniprotkb:Q13758|uniprotkb:Q13759|uniprotkb:Q15341|uniprotkb:Q15343|uniprotkb:Q16122|uniprotkb:Q16284|uniprotkb:Q16285|uniprotkb:Q16286|uniprotkb:Q16346|uniprotkb:Q16347|uniprotkb:Q92479|uniprotkb:A8MV94|uniprotkb:B2RMS4|uniprotkb:D3DSG1|ensembl:ENSP00000340690 psi-mi:sox2_human(display_long)|uniprotkb:SOX2(gene name)|psi-mi:SOX2(display_short) psi-mi:runx1_human(display_long)|uniprotkb:RUNX1(gene name)|psi-mi:RUNX1(display_short)|uniprotkb:AML1(gene name synonym)|uniprotkb:CBFA2(gene name synonym)|uniprotkb:Core-binding factor subunit alpha-2(gene name synonym)|uniprotkb:Acute myeloid leukemia 1 protein(gene name synonym)|uniprotkb:Oncogene AML-1(gene name synonym)|uniprotkb:Polyomavirus enhancer-binding protein 2 alpha B subunit(gene name synonym)|uniprotkb:SL3-3 enhancer factor 1 alpha B subunit(gene name synonym)|uniprotkb:SL3/AKV core-binding factor alpha B subunit(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Cox et al. (2012) pubmed:23667531|imex:IM-28599 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-26574619|imex:IM-28599-5 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_003097.1|dip:DIP-59913N|ensembl:ENSG00000181449(gene)|ensembl:ENST00000325404(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001649"(osteoblast differentiation)|go:"GO:0001654"(eye development)|go:"GO:0001714"(endodermal cell fate specification)|go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006325"(chromatin organization)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0009611"(response to wounding)|go:"GO:0009653"(anatomical structure morphogenesis)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0021781"(glial cell fate commitment)|go:"GO:0021983"(pituitary gland development)|go:"GO:0021984"(adenohypophysis development)|go:"GO:0022409"(positive regulation of cell-cell adhesion)|go:"GO:0030154"(cell differentiation)|go:"GO:0030900"(forebrain development)|go:"GO:0035019"(somatic stem cell population maintenance)|go:"GO:0035198"(miRNA binding)|go:"GO:0042246"(tissue regeneration)|go:"GO:0043281"(regulation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0043410"(positive regulation of MAPK cascade)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045165"(cell fate commitment)|go:"GO:0045597"(positive regulation of cell differentiation)|go:"GO:0045665"(negative regulation of neuron differentiation)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048839"(inner ear development)|go:"GO:0050680"(negative regulation of epithelial cell proliferation)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0070848"(response to growth factor)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:0097150"(neuronal stem cell population maintenance)|interpro:IPR009071(High mobility group box, HMG)|interpro:IPR022097|interpro:IPR032643|interpro:IPR036910|mint:P48431|rcsb pdb:1O4X|rcsb pdb:2LE4|rcsb pdb:6T7B|rcsb pdb:6T90|rcsb pdb:6WX7|rcsb pdb:6WX8|rcsb pdb:6WX9|rcsb pdb:6YOV|reactome:R-HSA-2892245|reactome:R-HSA-2892247|reactome:R-HSA-3769402|reactome:R-HSA-452723|reactome:R-HSA-6785807|reactome:R-HSA-8986944 refseq:XP_011528068.1|refseq:NP_001001890.1|refseq:NP_001116079.1|refseq:NP_001745.2|refseq:XP_005261125.1|dip:DIP-36773N|ensembl:ENSG00000159216(gene)|ensembl:ENST00000344691(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001503"(ossification)|go:"GO:0002062"(chondrocyte differentiation)|go:"GO:0002573"(myeloid leukocyte differentiation)|go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0008134"(transcription factor binding)|go:"GO:0010755"(regulation of plasminogen activation)|go:"GO:0016513"(core-binding factor complex)|go:"GO:0030097"(hemopoiesis)|go:"GO:0030099"(myeloid cell differentiation)|go:"GO:0030182"(neuron differentiation)|go:"GO:0030853"(negative regulation of granulocyte differentiation)|go:"GO:0030854"(positive regulation of granulocyte differentiation)|go:"GO:0032743"(positive regulation of interleukin-2 production)|go:"GO:0032967"(positive regulation of collagen biosynthetic process)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0043371"(negative regulation of CD4-positive, alpha-beta T cell differentiation)|go:"GO:0043378"(positive regulation of CD8-positive, alpha-beta T cell differentiation)|go:"GO:0045595"(regulation of cell differentiation)|go:"GO:0045766"(positive regulation of angiogenesis)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0048935"(peripheral nervous system neuron development)|go:"GO:0060043"(regulation of cardiac muscle cell proliferation)|go:"GO:0061026"(cardiac muscle tissue regeneration)|go:"GO:0071425"(hematopoietic stem cell proliferation)|go:"GO:1903055"(positive regulation of extracellular matrix organization)|go:"GO:1905203"(regulation of connective tissue replacement)|interpro:IPR000040("Acute myeloid leukemia 1 protein (AML 1)/Runt")|interpro:IPR008967(p53-like transcription factor, DNA-binding)|interpro:IPR012346(p53 and RUNT-type transcription factor, DNA-binding)|interpro:IPR013524("Acute myeloid leukemia 1 (AML 1)/Runt")|interpro:IPR013711(Runx inhibition)|interpro:IPR016554(Transcription factor, Runt-related, RUNX)|interpro:IPR027384|mint:Q01196|rcsb pdb:1CMO|rcsb pdb:1CO1|rcsb pdb:1E50|rcsb pdb:1H9D|rcsb pdb:1LJM|reactome:R-HSA-1912408|reactome:R-HSA-549127|reactome:R-HSA-8877330|reactome:R-HSA-8931987|reactome:R-HSA-8934593|reactome:R-HSA-8935964|reactome:R-HSA-8936459|reactome:R-HSA-8939236|reactome:R-HSA-8939242|reactome:R-HSA-8939243|reactome:R-HSA-8939245|reactome:R-HSA-8939246|reactome:R-HSA-8939247|reactome:R-HSA-8939256|reactome:R-HSA-8941333|reactome:R-HSA-8951936|reactome:R-HSA-9018519|reactome:R-HSA-9616222 go:"GO:0005634"(nucleus) - - figure legend:ST2 F2A|comment:proteins identified only in our induced samples in three MudPIT analyses with the more stringent BY-adjusted significance p<0.05|dataset:Brain Disease - Neurological Diseases & Disorders|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-daoy)|taxid:9606(Homo sapiens DAOY cerebellar medulloblastoma cell line) - 2020/12/29 2020/12/29 rogid:cn8gYfKDpQc8J2ygnqny32sIyyU9606 rogid:8RknoK1Z7L/Ck94Nd1b9/k03C8k9606 rigid:6EMs5+B89Q89RCR/2S2BG6PhH9E false tandem tag:n-n - - - psi-mi:"MI:0658"(multidimensional protein identification technology) psi-mi:"MI:0658"(multidimensional protein identification technology) uniprotkb:P48431 uniprotkb:P10071 intact:EBI-6124081|uniprotkb:Q14537|ensembl:ENSP00000323588 intact:EBI-308055|uniprotkb:A4D1W1|uniprotkb:O75219|uniprotkb:Q17RW4|uniprotkb:Q75MT0|uniprotkb:Q75MU9|uniprotkb:Q9UDT5|uniprotkb:Q9UJ39|ensembl:ENSP00000379258|ensembl:ENSP00000502957|ensembl:ENSP00000503743 psi-mi:sox2_human(display_long)|uniprotkb:SOX2(gene name)|psi-mi:SOX2(display_short) psi-mi:gli3_human(display_long)|uniprotkb:GLI3(gene name)|psi-mi:GLI3(display_short)|uniprotkb:GLI3 full-length protein(gene name synonym)|uniprotkb:GLI3 form of 190 kDa(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Cox et al. (2012) pubmed:23667531|imex:IM-28599 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-26574619|imex:IM-28599-5 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_003097.1|dip:DIP-59913N|ensembl:ENSG00000181449(gene)|ensembl:ENST00000325404(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001649"(osteoblast differentiation)|go:"GO:0001654"(eye development)|go:"GO:0001714"(endodermal cell fate specification)|go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006325"(chromatin organization)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0009611"(response to wounding)|go:"GO:0009653"(anatomical structure morphogenesis)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0021781"(glial cell fate commitment)|go:"GO:0021983"(pituitary gland development)|go:"GO:0021984"(adenohypophysis development)|go:"GO:0022409"(positive regulation of cell-cell adhesion)|go:"GO:0030154"(cell differentiation)|go:"GO:0030900"(forebrain development)|go:"GO:0035019"(somatic stem cell population maintenance)|go:"GO:0035198"(miRNA binding)|go:"GO:0042246"(tissue regeneration)|go:"GO:0043281"(regulation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0043410"(positive regulation of MAPK cascade)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045165"(cell fate commitment)|go:"GO:0045597"(positive regulation of cell differentiation)|go:"GO:0045665"(negative regulation of neuron differentiation)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048839"(inner ear development)|go:"GO:0050680"(negative regulation of epithelial cell proliferation)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0070848"(response to growth factor)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:0097150"(neuronal stem cell population maintenance)|interpro:IPR009071(High mobility group box, HMG)|interpro:IPR022097|interpro:IPR032643|interpro:IPR036910|mint:P48431|rcsb pdb:1O4X|rcsb pdb:2LE4|rcsb pdb:6T7B|rcsb pdb:6T90|rcsb pdb:6WX7|rcsb pdb:6WX8|rcsb pdb:6WX9|rcsb pdb:6YOV|reactome:R-HSA-2892245|reactome:R-HSA-2892247|reactome:R-HSA-3769402|reactome:R-HSA-452723|reactome:R-HSA-6785807|reactome:R-HSA-8986944 refseq:NP_000159.3|ensembl:ENSG00000106571(gene)|ensembl:ENST00000395925(transcript)|ensembl:ENST00000677605(transcript)|ensembl:ENST00000678429(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001656"(metanephros development)|go:"GO:0001658"(branching involved in ureteric bud morphogenesis)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0002052"(positive regulation of neuroblast proliferation)|go:"GO:0003682"(chromatin binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005929"(cilium)|go:"GO:0005930"(axoneme)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007224"(smoothened signaling pathway)|go:"GO:0007411"(axon guidance)|go:"GO:0007442"(hindgut morphogenesis)|go:"GO:0007507"(heart development)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0009952"(anterior/posterior pattern specification)|go:"GO:0009954"(proximal/distal pattern formation)|go:"GO:0016485"(protein processing)|go:"GO:0016607"(nuclear speck)|go:"GO:0017053"(transcription repressor complex)|go:"GO:0021631"(optic nerve morphogenesis)|go:"GO:0021766"(hippocampus development)|go:"GO:0021775"(smoothened signaling pathway involved in ventral spinal cord interneuron specification)|go:"GO:0021776"(smoothened signaling pathway involved in spinal cord motor neuron cell fate specification)|go:"GO:0021798"(forebrain dorsal/ventral pattern formation)|go:"GO:0021819"(layer formation in cerebral cortex)|go:"GO:0021861"(forebrain radial glial cell differentiation)|go:"GO:0022018"(lateral ganglionic eminence cell proliferation)|go:"GO:0030318"(melanocyte differentiation)|go:"GO:0030324"(lung development)|go:"GO:0030850"(prostate gland development)|go:"GO:0032332"(positive regulation of chondrocyte differentiation)|go:"GO:0033077"(T cell differentiation in thymus)|go:"GO:0035035"(histone acetyltransferase binding)|go:"GO:0035108"(limb morphogenesis)|go:"GO:0036033"(mediator complex binding)|go:"GO:0042060"(wound healing)|go:"GO:0042307"(positive regulation of protein import into nucleus)|go:"GO:0042475"(odontogenesis of dentin-containing tooth)|go:"GO:0042733"(embryonic digit morphogenesis)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0060594"(mammary gland specification)|go:"GO:0060831"(smoothened signaling pathway involved in dorsal/ventral neural tube patterning)|go:"GO:0060840"(artery development)|go:"GO:0060873"(anterior semicircular canal development)|go:"GO:0060875"(lateral semicircular canal development)|go:"GO:0061005"(cell differentiation involved in kidney development)|go:"GO:0070242"(thymocyte apoptotic process)|go:"GO:0071625"(vocalization behavior)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:0097421"(liver regeneration)|go:"GO:0097542"(ciliary tip)|go:"GO:0097546"(ciliary base)|go:"GO:0120223"(larynx morphogenesis)|go:"GO:1901620"(regulation of smoothened signaling pathway involved in dorsal/ventral neural tube patterning)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:1903010"(regulation of bone development)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0043585"(nose morphogenesis)|go:"GO:0043586"(tongue development)|go:"GO:0043627"(response to estrogen)|go:"GO:0045060"(negative thymic T cell selection)|go:"GO:0045665"(negative regulation of neuron differentiation)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR032851|interpro:IPR036236|interpro:IPR043359|go:"GO:0045669"(positive regulation of osteoblast differentiation)|go:"GO:0045879"(negative regulation of smoothened signaling pathway)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|mint:P10071|rcsb pdb:4BLD|reactome:R-HSA-5610785|reactome:R-HSA-5610787|reactome:R-HSA-5632684|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|reactome:R-HSA-5635851|reactome:R-HSA-8940973|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046638"(positive regulation of alpha-beta T cell differentiation)|go:"GO:0046639"(negative regulation of alpha-beta T cell differentiation)|go:"GO:0046872"(metal ion binding)|go:"GO:0048557"(embryonic digestive tract morphogenesis)|go:"GO:0048566"(embryonic digestive tract development)|go:"GO:0048589"(developmental growth)|go:"GO:0048593"(camera-type eye morphogenesis)|go:"GO:0048702"(embryonic neurocranium morphogenesis)|go:"GO:0048709"(oligodendrocyte differentiation)|go:"GO:0060021"(roof of mouth development)|go:"GO:0060364"(frontal suture morphogenesis)|go:"GO:0060366"(lambdoid suture morphogenesis)|go:"GO:0060367"(sagittal suture morphogenesis)|dip:DIP-32538N go:"GO:0005634"(nucleus) - - figure legend:ST2 F2A|comment:proteins identified only in our induced samples in three MudPIT analyses with the more stringent BY-adjusted significance p<0.05|dataset:Brain Disease - Neurological Diseases & Disorders|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-daoy)|taxid:9606(Homo sapiens DAOY cerebellar medulloblastoma cell line) - 2020/12/29 2020/12/29 rogid:cn8gYfKDpQc8J2ygnqny32sIyyU9606 rogid:BOHGgIuKgq0gUSahFeRaKnRmoMs9606 rigid:6EMs5+B89Q89RCR/2S2BG6PhH9E false tandem tag:n-n - - - psi-mi:"MI:0658"(multidimensional protein identification technology) psi-mi:"MI:0658"(multidimensional protein identification technology) uniprotkb:P48431 uniprotkb:O60930 intact:EBI-6124081|uniprotkb:Q14537|ensembl:ENSP00000323588 intact:EBI-2372399|uniprotkb:O60523|uniprotkb:O60857|uniprotkb:Q57Z93|uniprotkb:Q5U0C1|uniprotkb:Q6FHD4|uniprotkb:B3KQU4|ensembl:ENSP00000313350 psi-mi:sox2_human(display_long)|uniprotkb:SOX2(gene name)|psi-mi:SOX2(display_short) psi-mi:rnh1_human(display_long)|uniprotkb:RNASEH1(gene name)|psi-mi:RNASEH1(display_short)|uniprotkb:RNH1(gene name synonym)|uniprotkb:Ribonuclease H type II(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Cox et al. (2012) pubmed:23667531|imex:IM-28599 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-26574619|imex:IM-28599-5 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_003097.1|dip:DIP-59913N|ensembl:ENSG00000181449(gene)|ensembl:ENST00000325404(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001649"(osteoblast differentiation)|go:"GO:0001654"(eye development)|go:"GO:0001714"(endodermal cell fate specification)|go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006325"(chromatin organization)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0009611"(response to wounding)|go:"GO:0009653"(anatomical structure morphogenesis)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0021781"(glial cell fate commitment)|go:"GO:0021983"(pituitary gland development)|go:"GO:0021984"(adenohypophysis development)|go:"GO:0022409"(positive regulation of cell-cell adhesion)|go:"GO:0030154"(cell differentiation)|go:"GO:0030900"(forebrain development)|go:"GO:0035019"(somatic stem cell population maintenance)|go:"GO:0035198"(miRNA binding)|go:"GO:0042246"(tissue regeneration)|go:"GO:0043281"(regulation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0043410"(positive regulation of MAPK cascade)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045165"(cell fate commitment)|go:"GO:0045597"(positive regulation of cell differentiation)|go:"GO:0045665"(negative regulation of neuron differentiation)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048839"(inner ear development)|go:"GO:0050680"(negative regulation of epithelial cell proliferation)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0070848"(response to growth factor)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:0097150"(neuronal stem cell population maintenance)|interpro:IPR009071(High mobility group box, HMG)|interpro:IPR022097|interpro:IPR032643|interpro:IPR036910|mint:P48431|rcsb pdb:1O4X|rcsb pdb:2LE4|rcsb pdb:6T7B|rcsb pdb:6T90|rcsb pdb:6WX7|rcsb pdb:6WX8|rcsb pdb:6WX9|rcsb pdb:6YOV|reactome:R-HSA-2892245|reactome:R-HSA-2892247|reactome:R-HSA-3769402|reactome:R-HSA-452723|reactome:R-HSA-6785807|reactome:R-HSA-8986944 refseq:NP_002927.2|ensembl:ENSG00000171865(gene)|ensembl:ENST00000315212(transcript)|go:"GO:0000287"(magnesium ion binding)|go:"GO:0003676"(nucleic acid binding)|go:"GO:0003723"(RNA binding)|go:"GO:0004523"(RNA-DNA hybrid ribonuclease activity)|go:"GO:0004540"(ribonuclease activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0006401"(RNA catabolic process)|go:"GO:0043137"(DNA replication, removal of RNA primer)|go:"GO:0090502"(RNA phosphodiester bond hydrolysis, endonucleolytic)|interpro:IPR002156(Ribonuclease H)|interpro:IPR009027(Ribosomal protein L9 N-terminal-like)|interpro:IPR011320(Ribonuclease HI, N-terminal)|interpro:IPR012337(Polynucleotidyl transferase, Ribonuclease H fold)|interpro:IPR017067(Ribonuclease H1, eukaryote)|interpro:IPR036397|interpro:IPR037056|mint:O60930|rcsb pdb:2QK9|rcsb pdb:2QKB|rcsb pdb:2QKK|rcsb pdb:3BSU|rcsb pdb:6VRD go:"GO:0005634"(nucleus) - - figure legend:ST2 F2A|comment:proteins identified only in our induced samples in three MudPIT analyses with the more stringent BY-adjusted significance p<0.05|dataset:Brain Disease - Neurological Diseases & Disorders|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-daoy)|taxid:9606(Homo sapiens DAOY cerebellar medulloblastoma cell line) - 2020/12/29 2020/12/29 rogid:cn8gYfKDpQc8J2ygnqny32sIyyU9606 rogid:5ewRaIy98nsi0xPoW4OxG0dTHYU9606 rigid:6EMs5+B89Q89RCR/2S2BG6PhH9E false tandem tag:n-n - - - psi-mi:"MI:0658"(multidimensional protein identification technology) psi-mi:"MI:0658"(multidimensional protein identification technology) uniprotkb:P48431 uniprotkb:Q9HCN4 intact:EBI-6124081|uniprotkb:Q14537|ensembl:ENSP00000323588 intact:EBI-745137|uniprotkb:O76004|uniprotkb:B4DQJ5|uniprotkb:B4DXU4|uniprotkb:B4DQM4|ensembl:ENSP00000476446|uniprotkb:B5MBZ5 psi-mi:sox2_human(display_long)|uniprotkb:SOX2(gene name)|psi-mi:SOX2(display_short) psi-mi:gpn1_human(display_long)|uniprotkb:XAB1(gene name synonym)|uniprotkb:XPA-binding protein 1(gene name synonym)|uniprotkb:MBD2-interacting protein(gene name synonym)|uniprotkb:GPN1(gene name)|psi-mi:GPN1(display_short)|uniprotkb:MBDIN(gene name synonym)|uniprotkb:HUSSY-23(orf name)|uniprotkb:RNAPII-associated protein 4(gene name synonym)|uniprotkb:RPAP4(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Cox et al. (2012) pubmed:23667531|imex:IM-28599 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-26574619|imex:IM-28599-5 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_003097.1|dip:DIP-59913N|ensembl:ENSG00000181449(gene)|ensembl:ENST00000325404(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001649"(osteoblast differentiation)|go:"GO:0001654"(eye development)|go:"GO:0001714"(endodermal cell fate specification)|go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006325"(chromatin organization)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0009611"(response to wounding)|go:"GO:0009653"(anatomical structure morphogenesis)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0021781"(glial cell fate commitment)|go:"GO:0021983"(pituitary gland development)|go:"GO:0021984"(adenohypophysis development)|go:"GO:0022409"(positive regulation of cell-cell adhesion)|go:"GO:0030154"(cell differentiation)|go:"GO:0030900"(forebrain development)|go:"GO:0035019"(somatic stem cell population maintenance)|go:"GO:0035198"(miRNA binding)|go:"GO:0042246"(tissue regeneration)|go:"GO:0043281"(regulation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0043410"(positive regulation of MAPK cascade)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045165"(cell fate commitment)|go:"GO:0045597"(positive regulation of cell differentiation)|go:"GO:0045665"(negative regulation of neuron differentiation)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048839"(inner ear development)|go:"GO:0050680"(negative regulation of epithelial cell proliferation)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0070848"(response to growth factor)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:0097150"(neuronal stem cell population maintenance)|interpro:IPR009071(High mobility group box, HMG)|interpro:IPR022097|interpro:IPR032643|interpro:IPR036910|mint:P48431|rcsb pdb:1O4X|rcsb pdb:2LE4|rcsb pdb:6T7B|rcsb pdb:6T90|rcsb pdb:6WX7|rcsb pdb:6WX8|rcsb pdb:6WX9|rcsb pdb:6YOV|reactome:R-HSA-2892245|reactome:R-HSA-2892247|reactome:R-HSA-3769402|reactome:R-HSA-452723|reactome:R-HSA-6785807|reactome:R-HSA-8986944 refseq:NP_001138519.1|refseq:NP_001138520.1|refseq:NP_001138521.1|refseq:NP_009197.2|ensembl:ENSG00000198522(gene)|ensembl:ENST00000610189(transcript)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR004130(Protein of unknown function, ATP binding)|interpro:IPR027417|interpro:IPR030230|mint:Q9HCN4 go:"GO:0005634"(nucleus) - - figure legend:ST2 F2A|comment:proteins identified only in our induced samples in three MudPIT analyses with the more stringent BY-adjusted significance p<0.05|dataset:Brain Disease - Neurological Diseases & Disorders|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-daoy)|taxid:9606(Homo sapiens DAOY cerebellar medulloblastoma cell line) - 2020/12/29 2020/12/29 rogid:cn8gYfKDpQc8J2ygnqny32sIyyU9606 rogid:QZOTFh9d1hOcoG1DxAueYEwbOpc9606 rigid:6EMs5+B89Q89RCR/2S2BG6PhH9E false tandem tag:n-n - - - psi-mi:"MI:0658"(multidimensional protein identification technology) psi-mi:"MI:0658"(multidimensional protein identification technology) uniprotkb:P48431 uniprotkb:Q07960 intact:EBI-6124081|uniprotkb:Q14537|ensembl:ENSP00000323588 intact:EBI-602762|uniprotkb:D3DQQ6|ensembl:ENSP00000310491 psi-mi:sox2_human(display_long)|uniprotkb:SOX2(gene name)|psi-mi:SOX2(display_short) psi-mi:rhg01_human(display_long)|uniprotkb:Rho-type GTPase-activating protein 1(gene name synonym)|uniprotkb:Rho-related small GTPase protein activator(gene name synonym)|uniprotkb:p50-RhoGAP(gene name synonym)|uniprotkb:CDC42 GTPase-activating protein(gene name synonym)|uniprotkb:ARHGAP1(gene name)|psi-mi:ARHGAP1(display_short)|uniprotkb:CDC42GAP(gene name synonym)|uniprotkb:RHOGAP1(gene name synonym)|uniprotkb:GTPase-activating protein rhoGAP(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Cox et al. (2012) pubmed:23667531|imex:IM-28599 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-26574619|imex:IM-28599-5 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_003097.1|dip:DIP-59913N|ensembl:ENSG00000181449(gene)|ensembl:ENST00000325404(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001649"(osteoblast differentiation)|go:"GO:0001654"(eye development)|go:"GO:0001714"(endodermal cell fate specification)|go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006325"(chromatin organization)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0009611"(response to wounding)|go:"GO:0009653"(anatomical structure morphogenesis)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0021781"(glial cell fate commitment)|go:"GO:0021983"(pituitary gland development)|go:"GO:0021984"(adenohypophysis development)|go:"GO:0022409"(positive regulation of cell-cell adhesion)|go:"GO:0030154"(cell differentiation)|go:"GO:0030900"(forebrain development)|go:"GO:0035019"(somatic stem cell population maintenance)|go:"GO:0035198"(miRNA binding)|go:"GO:0042246"(tissue regeneration)|go:"GO:0043281"(regulation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0043410"(positive regulation of MAPK cascade)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045165"(cell fate commitment)|go:"GO:0045597"(positive regulation of cell differentiation)|go:"GO:0045665"(negative regulation of neuron differentiation)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048839"(inner ear development)|go:"GO:0050680"(negative regulation of epithelial cell proliferation)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0070848"(response to growth factor)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:0097150"(neuronal stem cell population maintenance)|interpro:IPR009071(High mobility group box, HMG)|interpro:IPR022097|interpro:IPR032643|interpro:IPR036910|mint:P48431|rcsb pdb:1O4X|rcsb pdb:2LE4|rcsb pdb:6T7B|rcsb pdb:6T90|rcsb pdb:6WX7|rcsb pdb:6WX8|rcsb pdb:6WX9|rcsb pdb:6YOV|reactome:R-HSA-2892245|reactome:R-HSA-2892247|reactome:R-HSA-3769402|reactome:R-HSA-452723|reactome:R-HSA-6785807|reactome:R-HSA-8986944 refseq:NP_004299.1|refseq:XP_011518397.1|dip:DIP-6081N|ensembl:ENSG00000175220(gene)|ensembl:ENST00000311956(transcript)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0007264"(small GTPase mediated signal transduction)|go:"GO:0007266"(Rho protein signal transduction)|go:"GO:0010008"(endosome membrane)|go:"GO:0016197"(endosomal transport)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0031267"(small GTPase binding)|go:"GO:0033572"(transferrin transport)|go:"GO:0045296"(cadherin binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051056"(regulation of small GTPase mediated signal transduction)|go:"GO:0070062"(extracellular exosome)|go:"GO:2001136"(negative regulation of endocytic recycling)|interpro:IPR000198(RhoGAP)|interpro:IPR001251(Cellular retinaldehyde-binding/triple function, C-terminal)|interpro:IPR008936(Rho GTPase activation protein)|interpro:IPR036865|mint:Q07960|rcsb pdb:1AM4|rcsb pdb:1GRN|rcsb pdb:1OW3|rcsb pdb:1RGP|rcsb pdb:1TX4|rcsb pdb:2NGR|rcsb pdb:5M6X|rcsb pdb:5M70|rcsb pdb:6R3V|reactome:R-HSA-8980692|reactome:R-HSA-9013026|reactome:R-HSA-9013106|reactome:R-HSA-9013148|reactome:R-HSA-9013149|reactome:R-HSA-9013404|reactome:R-HSA-9013405|reactome:R-HSA-9013406|reactome:R-HSA-9013408|reactome:R-HSA-9013409|reactome:R-HSA-9013423|reactome:R-HSA-9035034|reactome:R-HSA-9696270 go:"GO:0005634"(nucleus) - - figure legend:ST2 F2A|comment:proteins identified only in our induced samples in three MudPIT analyses with the more stringent BY-adjusted significance p<0.05|dataset:Brain Disease - Neurological Diseases & Disorders|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-daoy)|taxid:9606(Homo sapiens DAOY cerebellar medulloblastoma cell line) - 2020/12/29 2020/12/29 rogid:cn8gYfKDpQc8J2ygnqny32sIyyU9606 rogid:ceA3oLsnddhLiSbylS89P64mYBo9606 rigid:6EMs5+B89Q89RCR/2S2BG6PhH9E false tandem tag:n-n - - - psi-mi:"MI:0658"(multidimensional protein identification technology) psi-mi:"MI:0658"(multidimensional protein identification technology) uniprotkb:P48431 uniprotkb:P35712 intact:EBI-6124081|uniprotkb:Q14537|ensembl:ENSP00000323588 intact:EBI-3505706|uniprotkb:Q86VX7|uniprotkb:Q9BXQ3|uniprotkb:Q9BXQ4|uniprotkb:Q9BXQ5|uniprotkb:Q9H0I8|ensembl:ENSP00000433233|ensembl:ENSP00000507545 psi-mi:sox2_human(display_long)|uniprotkb:SOX2(gene name)|psi-mi:SOX2(display_short) psi-mi:sox6_human(display_long)|uniprotkb:SOX6(gene name)|psi-mi:SOX6(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Cox et al. (2012) pubmed:23667531|imex:IM-28599 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-26574619|imex:IM-28599-5 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_003097.1|dip:DIP-59913N|ensembl:ENSG00000181449(gene)|ensembl:ENST00000325404(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001649"(osteoblast differentiation)|go:"GO:0001654"(eye development)|go:"GO:0001714"(endodermal cell fate specification)|go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006325"(chromatin organization)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0009611"(response to wounding)|go:"GO:0009653"(anatomical structure morphogenesis)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0021781"(glial cell fate commitment)|go:"GO:0021983"(pituitary gland development)|go:"GO:0021984"(adenohypophysis development)|go:"GO:0022409"(positive regulation of cell-cell adhesion)|go:"GO:0030154"(cell differentiation)|go:"GO:0030900"(forebrain development)|go:"GO:0035019"(somatic stem cell population maintenance)|go:"GO:0035198"(miRNA binding)|go:"GO:0042246"(tissue regeneration)|go:"GO:0043281"(regulation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0043410"(positive regulation of MAPK cascade)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045165"(cell fate commitment)|go:"GO:0045597"(positive regulation of cell differentiation)|go:"GO:0045665"(negative regulation of neuron differentiation)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048839"(inner ear development)|go:"GO:0050680"(negative regulation of epithelial cell proliferation)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0070848"(response to growth factor)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:0097150"(neuronal stem cell population maintenance)|interpro:IPR009071(High mobility group box, HMG)|interpro:IPR022097|interpro:IPR032643|interpro:IPR036910|mint:P48431|rcsb pdb:1O4X|rcsb pdb:2LE4|rcsb pdb:6T7B|rcsb pdb:6T90|rcsb pdb:6WX7|rcsb pdb:6WX8|rcsb pdb:6WX9|rcsb pdb:6YOV|reactome:R-HSA-2892245|reactome:R-HSA-2892247|reactome:R-HSA-3769402|reactome:R-HSA-452723|reactome:R-HSA-6785807|reactome:R-HSA-8986944 refseq:NP_001139283.1|refseq:NP_001139291.1|refseq:NP_059978.1|refseq:NP_201583.2|ensembl:ENSG00000110693(gene)|ensembl:ENST00000528429(transcript)|ensembl:ENST00000683767(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001217"(DNA-binding transcription repressor activity)|go:"GO:0001502"(cartilage condensation)|go:"GO:0002062"(chondrocyte differentiation)|go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007417"(central nervous system development)|go:"GO:0007420"(brain development)|go:"GO:0007517"(muscle organ development)|go:"GO:0021529"(spinal cord oligodendrocyte cell differentiation)|go:"GO:0032332"(positive regulation of chondrocyte differentiation)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0045165"(cell fate commitment)|go:"GO:0051216"(cartilage development)|go:"GO:0061036"(positive regulation of cartilage development)|go:"GO:0071560"(cellular response to transforming growth factor beta stimulus)|go:"GO:2000726"(negative regulation of cardiac muscle cell differentiation)|go:"GO:2000741"(positive regulation of mesenchymal stem cell differentiation)|interpro:IPR009071(High mobility group box, HMG)|interpro:IPR027153|interpro:IPR036910|mint:P35712|reactome:R-HSA-3769402 go:"GO:0005634"(nucleus) - - figure legend:ST2 F2A|comment:proteins identified only in our induced samples in three MudPIT analyses with the more stringent BY-adjusted significance p<0.05|dataset:Brain Disease - Neurological Diseases & Disorders|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-daoy)|taxid:9606(Homo sapiens DAOY cerebellar medulloblastoma cell line) - 2020/12/29 2020/12/29 rogid:cn8gYfKDpQc8J2ygnqny32sIyyU9606 rogid:UV6EBIPo7xAUw/24j8y9bwJpOg49606 rigid:6EMs5+B89Q89RCR/2S2BG6PhH9E false tandem tag:n-n - - - psi-mi:"MI:0658"(multidimensional protein identification technology) psi-mi:"MI:0658"(multidimensional protein identification technology) uniprotkb:P48431 uniprotkb:Q5PRF9 intact:EBI-6124081|uniprotkb:Q14537|ensembl:ENSP00000323588 intact:EBI-1047489|uniprotkb:Q6P194|intact:EBI-1058937|ensembl:ENSP00000317224|ensembl:ENSP00000484229|uniprotkb:A5Z0M6 psi-mi:sox2_human(display_long)|uniprotkb:SOX2(gene name)|psi-mi:SOX2(display_short) psi-mi:smag2_human(display_long)|uniprotkb:SAMD4B(gene name)|psi-mi:SAMD4B(display_short)|uniprotkb:SMAUG2(gene name synonym)|uniprotkb:Sterile alpha motif domain-containing protein 4B(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Cox et al. (2012) pubmed:23667531|imex:IM-28599 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-26574619|imex:IM-28599-5 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_003097.1|dip:DIP-59913N|ensembl:ENSG00000181449(gene)|ensembl:ENST00000325404(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001649"(osteoblast differentiation)|go:"GO:0001654"(eye development)|go:"GO:0001714"(endodermal cell fate specification)|go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006325"(chromatin organization)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0009611"(response to wounding)|go:"GO:0009653"(anatomical structure morphogenesis)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0021781"(glial cell fate commitment)|go:"GO:0021983"(pituitary gland development)|go:"GO:0021984"(adenohypophysis development)|go:"GO:0022409"(positive regulation of cell-cell adhesion)|go:"GO:0030154"(cell differentiation)|go:"GO:0030900"(forebrain development)|go:"GO:0035019"(somatic stem cell population maintenance)|go:"GO:0035198"(miRNA binding)|go:"GO:0042246"(tissue regeneration)|go:"GO:0043281"(regulation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0043410"(positive regulation of MAPK cascade)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045165"(cell fate commitment)|go:"GO:0045597"(positive regulation of cell differentiation)|go:"GO:0045665"(negative regulation of neuron differentiation)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048839"(inner ear development)|go:"GO:0050680"(negative regulation of epithelial cell proliferation)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0070848"(response to growth factor)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:0097150"(neuronal stem cell population maintenance)|interpro:IPR009071(High mobility group box, HMG)|interpro:IPR022097|interpro:IPR032643|interpro:IPR036910|mint:P48431|rcsb pdb:1O4X|rcsb pdb:2LE4|rcsb pdb:6T7B|rcsb pdb:6T90|rcsb pdb:6WX7|rcsb pdb:6WX8|rcsb pdb:6WX9|rcsb pdb:6YOV|reactome:R-HSA-2892245|reactome:R-HSA-2892247|reactome:R-HSA-3769402|reactome:R-HSA-452723|reactome:R-HSA-6785807|reactome:R-HSA-8986944 refseq:NP_060498.2|ensembl:ENSG00000179134(gene)|ensembl:ENST00000314471(transcript)|ensembl:ENST00000610417(transcript)|go:"GO:0000289"("nuclear-transcribed mRNA poly(A) tail shortening")|go:"GO:0000932"(P-body)|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0017148"(negative regulation of translation)|go:"GO:0030371"(translation repressor activity)|go:"GO:0043488"(regulation of mRNA stability)|interpro:IPR001660(Sterile alpha motif SAM)|interpro:IPR013761(Sterile alpha motif-type)|interpro:IPR037093|refseq:NP_001290543.1|refseq:XP_011525365.1|refseq:XP_016882409.1|refseq:XP_016882410.1|interpro:IPR037634|mint:Q5PRF9 go:"GO:0005634"(nucleus) - - figure legend:ST2 F2A|comment:proteins identified only in our induced samples in three MudPIT analyses with the more stringent BY-adjusted significance p<0.05|dataset:Brain Disease - Neurological Diseases & Disorders|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-daoy)|taxid:9606(Homo sapiens DAOY cerebellar medulloblastoma cell line) - 2020/12/29 2020/12/29 rogid:cn8gYfKDpQc8J2ygnqny32sIyyU9606 rogid:ySsXY/QTS58Li20O66/ICk4wwOg9606 rigid:6EMs5+B89Q89RCR/2S2BG6PhH9E false tandem tag:n-n - - - psi-mi:"MI:0658"(multidimensional protein identification technology) psi-mi:"MI:0658"(multidimensional protein identification technology) uniprotkb:P48431 uniprotkb:Q5TA45 intact:EBI-6124081|uniprotkb:Q14537|ensembl:ENSP00000323588 intact:EBI-748258|uniprotkb:Q5TA46|uniprotkb:Q5TA48|uniprotkb:Q5TA52|uniprotkb:Q5TA53|uniprotkb:Q5TA54|uniprotkb:Q7L3D7|uniprotkb:Q96HY1|uniprotkb:Q9BW36|uniprotkb:Q9H0F9|uniprotkb:Q9H8R5|uniprotkb:Q9HAA6|uniprotkb:Q9NWX9|uniprotkb:B4DM87|uniprotkb:A8K5S2|uniprotkb:B3KPR3|uniprotkb:G3V1S5|ensembl:ENSP00000413493 psi-mi:sox2_human(display_long)|uniprotkb:SOX2(gene name)|psi-mi:SOX2(display_short) psi-mi:int11_human(display_long)|uniprotkb:INTS11(gene name)|psi-mi:INTS11(display_short)|uniprotkb:CPSF3L(gene name synonym)|uniprotkb:Cleavage and polyadenylation-specific factor 3-like protein(gene name synonym)|uniprotkb:Protein related to CPSF subunits of 68 kDa(gene name synonym)|uniprotkb:RC68(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Cox et al. (2012) pubmed:23667531|imex:IM-28599 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-26574619|imex:IM-28599-5 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_003097.1|dip:DIP-59913N|ensembl:ENSG00000181449(gene)|ensembl:ENST00000325404(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001649"(osteoblast differentiation)|go:"GO:0001654"(eye development)|go:"GO:0001714"(endodermal cell fate specification)|go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006325"(chromatin organization)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0009611"(response to wounding)|go:"GO:0009653"(anatomical structure morphogenesis)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0021781"(glial cell fate commitment)|go:"GO:0021983"(pituitary gland development)|go:"GO:0021984"(adenohypophysis development)|go:"GO:0022409"(positive regulation of cell-cell adhesion)|go:"GO:0030154"(cell differentiation)|go:"GO:0030900"(forebrain development)|go:"GO:0035019"(somatic stem cell population maintenance)|go:"GO:0035198"(miRNA binding)|go:"GO:0042246"(tissue regeneration)|go:"GO:0043281"(regulation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0043410"(positive regulation of MAPK cascade)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045165"(cell fate commitment)|go:"GO:0045597"(positive regulation of cell differentiation)|go:"GO:0045665"(negative regulation of neuron differentiation)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048839"(inner ear development)|go:"GO:0050680"(negative regulation of epithelial cell proliferation)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0070848"(response to growth factor)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:0097150"(neuronal stem cell population maintenance)|interpro:IPR009071(High mobility group box, HMG)|interpro:IPR022097|interpro:IPR032643|interpro:IPR036910|mint:P48431|rcsb pdb:1O4X|rcsb pdb:2LE4|rcsb pdb:6T7B|rcsb pdb:6T90|rcsb pdb:6WX7|rcsb pdb:6WX8|rcsb pdb:6WX9|rcsb pdb:6YOV|reactome:R-HSA-2892245|reactome:R-HSA-2892247|reactome:R-HSA-3769402|reactome:R-HSA-452723|reactome:R-HSA-6785807|reactome:R-HSA-8986944 refseq:NP_060341.2|refseq:NP_001243392.1|refseq:NP_001243385.1|refseq:NP_001243389.1|refseq:NP_001243391.1|ensembl:ENSG00000127054(gene)|ensembl:ENST00000435064(transcript)|go:"GO:0004521"(endoribonuclease activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0016180"(snRNA processing)|go:"GO:0032039"(integrator complex)|go:"GO:0072562"(blood microparticle)|interpro:IPR001279(Beta-lactamase-like)|interpro:IPR011108(RNA-metabolising metallo-beta-lactamase)|interpro:IPR022712|interpro:IPR036866|interpro:IPR041897|mint:Q5TA45|rcsb pdb:5V8W|rcsb pdb:7BFP|rcsb pdb:7BFQ|rcsb pdb:7CUN|reactome:R-HSA-6807505 go:"GO:0005634"(nucleus) - - figure legend:ST2 F2A|comment:proteins identified only in our induced samples in three MudPIT analyses with the more stringent BY-adjusted significance p<0.05|dataset:Brain Disease - Neurological Diseases & Disorders|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-daoy)|taxid:9606(Homo sapiens DAOY cerebellar medulloblastoma cell line) - 2020/12/29 2020/12/29 rogid:cn8gYfKDpQc8J2ygnqny32sIyyU9606 rogid:fKmUHJl/uR84eTlB28zhADznkXQ9606 rigid:6EMs5+B89Q89RCR/2S2BG6PhH9E false tandem tag:n-n - - - psi-mi:"MI:0658"(multidimensional protein identification technology) psi-mi:"MI:0658"(multidimensional protein identification technology) uniprotkb:P48431 uniprotkb:Q9NVH2 intact:EBI-6124081|uniprotkb:Q14537|ensembl:ENSP00000323588 intact:EBI-11276282|uniprotkb:B4DLZ6|uniprotkb:B7WNP6|uniprotkb:B7WPB6|uniprotkb:Q8N4K7|uniprotkb:Q8WUH5|uniprotkb:Q9H9V3|uniprotkb:Q9NVU5|uniprotkb:Q9UFC6|uniprotkb:Q9UFM3|ensembl:ENSP00000355961 psi-mi:sox2_human(display_long)|uniprotkb:SOX2(gene name)|psi-mi:SOX2(display_short) psi-mi:int7_human(display_long)|uniprotkb:INTS7(gene name)|psi-mi:INTS7(display_short)|uniprotkb:C1orf73(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Cox et al. (2012) pubmed:23667531|imex:IM-28599 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-26574619|imex:IM-28599-5 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_003097.1|dip:DIP-59913N|ensembl:ENSG00000181449(gene)|ensembl:ENST00000325404(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001649"(osteoblast differentiation)|go:"GO:0001654"(eye development)|go:"GO:0001714"(endodermal cell fate specification)|go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006325"(chromatin organization)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0009611"(response to wounding)|go:"GO:0009653"(anatomical structure morphogenesis)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0021781"(glial cell fate commitment)|go:"GO:0021983"(pituitary gland development)|go:"GO:0021984"(adenohypophysis development)|go:"GO:0022409"(positive regulation of cell-cell adhesion)|go:"GO:0030154"(cell differentiation)|go:"GO:0030900"(forebrain development)|go:"GO:0035019"(somatic stem cell population maintenance)|go:"GO:0035198"(miRNA binding)|go:"GO:0042246"(tissue regeneration)|go:"GO:0043281"(regulation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0043410"(positive regulation of MAPK cascade)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045165"(cell fate commitment)|go:"GO:0045597"(positive regulation of cell differentiation)|go:"GO:0045665"(negative regulation of neuron differentiation)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048839"(inner ear development)|go:"GO:0050680"(negative regulation of epithelial cell proliferation)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0070848"(response to growth factor)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:0097150"(neuronal stem cell population maintenance)|interpro:IPR009071(High mobility group box, HMG)|interpro:IPR022097|interpro:IPR032643|interpro:IPR036910|mint:P48431|rcsb pdb:1O4X|rcsb pdb:2LE4|rcsb pdb:6T7B|rcsb pdb:6T90|rcsb pdb:6WX7|rcsb pdb:6WX8|rcsb pdb:6WX9|rcsb pdb:6YOV|reactome:R-HSA-2892245|reactome:R-HSA-2892247|reactome:R-HSA-3769402|reactome:R-HSA-452723|reactome:R-HSA-6785807|reactome:R-HSA-8986944 refseq:NP_001186738.1|refseq:NP_001186740.1|refseq:NP_001186741.1|refseq:NP_056249.1|ensembl:ENSG00000143493(gene)|ensembl:ENST00000366994(transcript)|go:"GO:0000077"(DNA damage checkpoint signaling)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005694"(chromosome)|go:"GO:0005737"(cytoplasm)|go:"GO:0016180"(snRNA processing)|go:"GO:0016604"(nuclear body)|go:"GO:0032039"(integrator complex)|go:"GO:0034472"(snRNA 3'-end processing)|go:"GO:0071479"(cellular response to ionizing radiation)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR033060|mint:Q9NVH2|rcsb pdb:7CUN|reactome:R-HSA-6807505 go:"GO:0005634"(nucleus) - - figure legend:ST2 F2A|comment:proteins identified only in our induced samples in three MudPIT analyses with the more stringent BY-adjusted significance p<0.05|dataset:Brain Disease - Neurological Diseases & Disorders|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-daoy)|taxid:9606(Homo sapiens DAOY cerebellar medulloblastoma cell line) - 2020/12/29 2020/12/29 rogid:cn8gYfKDpQc8J2ygnqny32sIyyU9606 rogid:PqhjJZUeAkdQHmckoWrwfsPUUeI9606 rigid:6EMs5+B89Q89RCR/2S2BG6PhH9E false tandem tag:n-n - - - psi-mi:"MI:0658"(multidimensional protein identification technology) psi-mi:"MI:0658"(multidimensional protein identification technology) uniprotkb:P48431 uniprotkb:P22670 intact:EBI-6124081|uniprotkb:Q14537|ensembl:ENSP00000323588 intact:EBI-716037|ensembl:ENSP00000254325|ensembl:ENSP00000500760 psi-mi:sox2_human(display_long)|uniprotkb:SOX2(gene name)|psi-mi:SOX2(display_short) psi-mi:rfx1_human(display_long)|uniprotkb:Transcription factor RFX1(gene name synonym)|uniprotkb:Regulatory factor X 1(gene name synonym)|uniprotkb:Enhancer factor C(gene name synonym)|uniprotkb:RFX1(gene name)|psi-mi:RFX1(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Cox et al. (2012) pubmed:23667531|imex:IM-28599 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-26574619|imex:IM-28599-5 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_003097.1|dip:DIP-59913N|ensembl:ENSG00000181449(gene)|ensembl:ENST00000325404(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001649"(osteoblast differentiation)|go:"GO:0001654"(eye development)|go:"GO:0001714"(endodermal cell fate specification)|go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006325"(chromatin organization)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0009611"(response to wounding)|go:"GO:0009653"(anatomical structure morphogenesis)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0021781"(glial cell fate commitment)|go:"GO:0021983"(pituitary gland development)|go:"GO:0021984"(adenohypophysis development)|go:"GO:0022409"(positive regulation of cell-cell adhesion)|go:"GO:0030154"(cell differentiation)|go:"GO:0030900"(forebrain development)|go:"GO:0035019"(somatic stem cell population maintenance)|go:"GO:0035198"(miRNA binding)|go:"GO:0042246"(tissue regeneration)|go:"GO:0043281"(regulation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0043410"(positive regulation of MAPK cascade)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045165"(cell fate commitment)|go:"GO:0045597"(positive regulation of cell differentiation)|go:"GO:0045665"(negative regulation of neuron differentiation)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048839"(inner ear development)|go:"GO:0050680"(negative regulation of epithelial cell proliferation)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0070848"(response to growth factor)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:0097150"(neuronal stem cell population maintenance)|interpro:IPR009071(High mobility group box, HMG)|interpro:IPR022097|interpro:IPR032643|interpro:IPR036910|mint:P48431|rcsb pdb:1O4X|rcsb pdb:2LE4|rcsb pdb:6T7B|rcsb pdb:6T90|rcsb pdb:6WX7|rcsb pdb:6WX8|rcsb pdb:6WX9|rcsb pdb:6YOV|reactome:R-HSA-2892245|reactome:R-HSA-2892247|reactome:R-HSA-3769402|reactome:R-HSA-452723|reactome:R-HSA-6785807|reactome:R-HSA-8986944 refseq:NP_002909.4|ensembl:ENSG00000288283(gene)|ensembl:ENST00000254325(transcript)|ensembl:ENST00000672295(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006955"(immune response)|go:"GO:0043231"(intracellular membrane-bounded organelle)|ensembl:ENSG00000132005(gene)|interpro:IPR003150(DNA-binding RFX)|interpro:IPR007668(RFX1 transcription activation region)|interpro:IPR036388|interpro:IPR036390|interpro:IPR039779|mint:P22670|rcsb pdb:1DP7|go:"GO:1990837"(sequence-specific double-stranded DNA binding) go:"GO:0005634"(nucleus) - - figure legend:ST2 F2A|comment:proteins identified only in our induced samples in three MudPIT analyses with the more stringent BY-adjusted significance p<0.05|dataset:Brain Disease - Neurological Diseases & Disorders|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-daoy)|taxid:9606(Homo sapiens DAOY cerebellar medulloblastoma cell line) - 2020/12/29 2020/12/29 rogid:cn8gYfKDpQc8J2ygnqny32sIyyU9606 rogid:wuth5iU8m39Wo6gmcElDKuF2pLs9606 rigid:6EMs5+B89Q89RCR/2S2BG6PhH9E false tandem tag:n-n - - - psi-mi:"MI:0658"(multidimensional protein identification technology) psi-mi:"MI:0658"(multidimensional protein identification technology) uniprotkb:P48431 uniprotkb:O15014 intact:EBI-6124081|uniprotkb:Q14537|ensembl:ENSP00000323588 intact:EBI-948874|intact:EBI-28988504|ensembl:ENSP00000316527|uniprotkb:Q0D2I2 psi-mi:sox2_human(display_long)|uniprotkb:SOX2(gene name)|psi-mi:SOX2(display_short) psi-mi:zn609_human(display_long)|uniprotkb:ZNF609(gene name)|psi-mi:ZNF609(display_short)|uniprotkb:KIAA0295(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Cox et al. (2012) pubmed:23667531|imex:IM-28599 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-26574619|imex:IM-28599-5 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_003097.1|dip:DIP-59913N|ensembl:ENSG00000181449(gene)|ensembl:ENST00000325404(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001649"(osteoblast differentiation)|go:"GO:0001654"(eye development)|go:"GO:0001714"(endodermal cell fate specification)|go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006325"(chromatin organization)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0009611"(response to wounding)|go:"GO:0009653"(anatomical structure morphogenesis)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0021781"(glial cell fate commitment)|go:"GO:0021983"(pituitary gland development)|go:"GO:0021984"(adenohypophysis development)|go:"GO:0022409"(positive regulation of cell-cell adhesion)|go:"GO:0030154"(cell differentiation)|go:"GO:0030900"(forebrain development)|go:"GO:0035019"(somatic stem cell population maintenance)|go:"GO:0035198"(miRNA binding)|go:"GO:0042246"(tissue regeneration)|go:"GO:0043281"(regulation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0043410"(positive regulation of MAPK cascade)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045165"(cell fate commitment)|go:"GO:0045597"(positive regulation of cell differentiation)|go:"GO:0045665"(negative regulation of neuron differentiation)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048839"(inner ear development)|go:"GO:0050680"(negative regulation of epithelial cell proliferation)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0070848"(response to growth factor)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:0097150"(neuronal stem cell population maintenance)|interpro:IPR009071(High mobility group box, HMG)|interpro:IPR022097|interpro:IPR032643|interpro:IPR036910|mint:P48431|rcsb pdb:1O4X|rcsb pdb:2LE4|rcsb pdb:6T7B|rcsb pdb:6T90|rcsb pdb:6WX7|rcsb pdb:6WX8|rcsb pdb:6WX9|rcsb pdb:6YOV|reactome:R-HSA-2892245|reactome:R-HSA-2892247|reactome:R-HSA-3769402|reactome:R-HSA-452723|reactome:R-HSA-6785807|reactome:R-HSA-8986944 dip:DIP-50012N|ensembl:ENSG00000180357(gene)|ensembl:ENST00000326648(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007517"(muscle organ development)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|go:"GO:1990841"(promoter-specific chromatin binding)|go:"GO:2000291"(regulation of myoblast proliferation)|go:"GO:2001224"(positive regulation of neuron migration)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR040010|mint:O15014|refseq:NP_055857.1|refseq:XP_011519688.1|ensembl:ENSP00000316527|refseq:XP_016877510.1 go:"GO:0005634"(nucleus) - - figure legend:ST2 F2A|comment:proteins identified only in our induced samples in three MudPIT analyses with the more stringent BY-adjusted significance p<0.05|dataset:Brain Disease - Neurological Diseases & Disorders|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-daoy)|taxid:9606(Homo sapiens DAOY cerebellar medulloblastoma cell line) - 2020/12/29 2020/12/29 rogid:cn8gYfKDpQc8J2ygnqny32sIyyU9606 rogid:lg9CqF10xeIzDGib19G9feQpBIY9606 rigid:6EMs5+B89Q89RCR/2S2BG6PhH9E false tandem tag:n-n - - - psi-mi:"MI:0658"(multidimensional protein identification technology) psi-mi:"MI:0658"(multidimensional protein identification technology) uniprotkb:P48431 uniprotkb:O00257 intact:EBI-6124081|uniprotkb:Q14537|ensembl:ENSP00000323588 intact:EBI-722425|uniprotkb:Q96C04|uniprotkb:Q6TPI8|uniprotkb:B1PJR7|ensembl:ENSP00000269397 psi-mi:sox2_human(display_long)|uniprotkb:SOX2(gene name)|psi-mi:SOX2(display_short) psi-mi:cbx4_human(display_long)|uniprotkb:Chromobox protein homolog 4(gene name synonym)|uniprotkb:Polycomb 2 homolog(gene name synonym)|uniprotkb:CBX4(gene name)|psi-mi:CBX4(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Cox et al. (2012) pubmed:23667531|imex:IM-28599 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-26574619|imex:IM-28599-5 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_003097.1|dip:DIP-59913N|ensembl:ENSG00000181449(gene)|ensembl:ENST00000325404(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001649"(osteoblast differentiation)|go:"GO:0001654"(eye development)|go:"GO:0001714"(endodermal cell fate specification)|go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006325"(chromatin organization)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0009611"(response to wounding)|go:"GO:0009653"(anatomical structure morphogenesis)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0021781"(glial cell fate commitment)|go:"GO:0021983"(pituitary gland development)|go:"GO:0021984"(adenohypophysis development)|go:"GO:0022409"(positive regulation of cell-cell adhesion)|go:"GO:0030154"(cell differentiation)|go:"GO:0030900"(forebrain development)|go:"GO:0035019"(somatic stem cell population maintenance)|go:"GO:0035198"(miRNA binding)|go:"GO:0042246"(tissue regeneration)|go:"GO:0043281"(regulation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0043410"(positive regulation of MAPK cascade)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045165"(cell fate commitment)|go:"GO:0045597"(positive regulation of cell differentiation)|go:"GO:0045665"(negative regulation of neuron differentiation)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048839"(inner ear development)|go:"GO:0050680"(negative regulation of epithelial cell proliferation)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0070848"(response to growth factor)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:0097150"(neuronal stem cell population maintenance)|interpro:IPR009071(High mobility group box, HMG)|interpro:IPR022097|interpro:IPR032643|interpro:IPR036910|mint:P48431|rcsb pdb:1O4X|rcsb pdb:2LE4|rcsb pdb:6T7B|rcsb pdb:6T90|rcsb pdb:6WX7|rcsb pdb:6WX8|rcsb pdb:6WX9|rcsb pdb:6YOV|reactome:R-HSA-2892245|reactome:R-HSA-2892247|reactome:R-HSA-3769402|reactome:R-HSA-452723|reactome:R-HSA-6785807|reactome:R-HSA-8986944 refseq:NP_003646.2|dip:DIP-42042N|ensembl:ENSG00000141582(gene)|ensembl:ENST00000269397(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0003727"(single-stranded RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006325"(chromatin organization)|go:"GO:0016604"(nuclear body)|go:"GO:0016607"(nuclear speck)|go:"GO:0019789"(SUMO transferase activity)|go:"GO:0019899"(enzyme binding)|go:"GO:0031519"(PcG protein complex)|go:"GO:0032183"(SUMO binding)|go:"GO:0035064"(methylated histone binding)|go:"GO:0035102"(PRC1 complex)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0051219"(phosphoprotein binding)|go:"GO:0061665"(SUMO ligase activity)|interpro:IPR000953(Chromo domain)|interpro:IPR016197(Chromo domain-like)|interpro:IPR017984|interpro:IPR023779|interpro:IPR023780|interpro:IPR033773|interpro:IPR043531|mint:O00257|rcsb pdb:2K28|rcsb pdb:3I8Z|rcsb pdb:5EPL|reactome:R-HSA-2559580|reactome:R-HSA-3108214|reactome:R-HSA-3899300|reactome:R-HSA-4551638|reactome:R-HSA-4570464|reactome:R-HSA-4655427|reactome:R-HSA-8939243|reactome:R-HSA-8943724 go:"GO:0005634"(nucleus) - - figure legend:ST2 F2A|comment:proteins identified only in our induced samples in three MudPIT analyses with the more stringent BY-adjusted significance p<0.05|dataset:Brain Disease - Neurological Diseases & Disorders|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-daoy)|taxid:9606(Homo sapiens DAOY cerebellar medulloblastoma cell line) - 2020/12/29 2020/12/29 rogid:cn8gYfKDpQc8J2ygnqny32sIyyU9606 rogid:uHX633+6nZPTNHOPmUKK+zW/b4Q9606 rigid:6EMs5+B89Q89RCR/2S2BG6PhH9E false tandem tag:n-n - - - psi-mi:"MI:0658"(multidimensional protein identification technology) psi-mi:"MI:0658"(multidimensional protein identification technology) uniprotkb:P48431 uniprotkb:Q6DD87 intact:EBI-6124081|uniprotkb:Q14537|ensembl:ENSP00000323588 intact:EBI-5457592|uniprotkb:A0A087WUD1|uniprotkb:O00455|ensembl:ENSP00000478557 psi-mi:sox2_human(display_long)|uniprotkb:SOX2(gene name)|psi-mi:SOX2(display_short) psi-mi:zn787_human(display_long)|uniprotkb:ZNF787(gene name)|psi-mi:ZNF787(display_short)|uniprotkb:TTF-I-interacting peptide 20(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Cox et al. (2012) pubmed:23667531|imex:IM-28599 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-26574619|imex:IM-28599-5 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_003097.1|dip:DIP-59913N|ensembl:ENSG00000181449(gene)|ensembl:ENST00000325404(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001649"(osteoblast differentiation)|go:"GO:0001654"(eye development)|go:"GO:0001714"(endodermal cell fate specification)|go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006325"(chromatin organization)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0009611"(response to wounding)|go:"GO:0009653"(anatomical structure morphogenesis)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0021781"(glial cell fate commitment)|go:"GO:0021983"(pituitary gland development)|go:"GO:0021984"(adenohypophysis development)|go:"GO:0022409"(positive regulation of cell-cell adhesion)|go:"GO:0030154"(cell differentiation)|go:"GO:0030900"(forebrain development)|go:"GO:0035019"(somatic stem cell population maintenance)|go:"GO:0035198"(miRNA binding)|go:"GO:0042246"(tissue regeneration)|go:"GO:0043281"(regulation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0043410"(positive regulation of MAPK cascade)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045165"(cell fate commitment)|go:"GO:0045597"(positive regulation of cell differentiation)|go:"GO:0045665"(negative regulation of neuron differentiation)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048839"(inner ear development)|go:"GO:0050680"(negative regulation of epithelial cell proliferation)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0070848"(response to growth factor)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:0097150"(neuronal stem cell population maintenance)|interpro:IPR009071(High mobility group box, HMG)|interpro:IPR022097|interpro:IPR032643|interpro:IPR036910|mint:P48431|rcsb pdb:1O4X|rcsb pdb:2LE4|rcsb pdb:6T7B|rcsb pdb:6T90|rcsb pdb:6WX7|rcsb pdb:6WX8|rcsb pdb:6WX9|rcsb pdb:6YOV|reactome:R-HSA-2892245|reactome:R-HSA-2892247|reactome:R-HSA-3769402|reactome:R-HSA-452723|reactome:R-HSA-6785807|reactome:R-HSA-8986944 refseq:NP_001002836.2|refseq:XP_011524747.1|ensembl:ENSG00000142409(gene)|ensembl:ENST00000610935(transcript)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0046872"(metal ion binding)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR036236|mint:Q6DD87 go:"GO:0005634"(nucleus) - - figure legend:ST2 F2A|comment:proteins identified only in our induced samples in three MudPIT analyses with the more stringent BY-adjusted significance p<0.05|dataset:Brain Disease - Neurological Diseases & Disorders|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-daoy)|taxid:9606(Homo sapiens DAOY cerebellar medulloblastoma cell line) - 2020/12/29 2020/12/29 rogid:cn8gYfKDpQc8J2ygnqny32sIyyU9606 rogid:B25i4bTxTWsGThUtdlCr4DnweoE9606 rigid:6EMs5+B89Q89RCR/2S2BG6PhH9E false tandem tag:n-n - - - psi-mi:"MI:0658"(multidimensional protein identification technology) psi-mi:"MI:0658"(multidimensional protein identification technology) uniprotkb:P48431 uniprotkb:Q6PIY7 intact:EBI-6124081|uniprotkb:Q14537|ensembl:ENSP00000323588 intact:EBI-2802204|uniprotkb:Q86WZ2|uniprotkb:Q8N927|ensembl:ENSP00000296783|ensembl:ENSP00000396861|ensembl:ENSP00000397563 psi-mi:sox2_human(display_long)|uniprotkb:SOX2(gene name)|psi-mi:SOX2(display_short) psi-mi:gld2_human(display_long)|uniprotkb:TENT2(gene name)|psi-mi:TENT2(display_short)|uniprotkb:GLD2(gene name synonym)|uniprotkb:PAP-associated domain-containing protein 4(gene name synonym)|uniprotkb:PAPD4(gene name synonym)|uniprotkb:Terminal nucleotidyltransferase 2(gene name synonym)|uniprotkb:Terminal uridylyltransferase 2(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Cox et al. (2012) pubmed:23667531|imex:IM-28599 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-26574619|imex:IM-28599-5 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_003097.1|dip:DIP-59913N|ensembl:ENSG00000181449(gene)|ensembl:ENST00000325404(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001649"(osteoblast differentiation)|go:"GO:0001654"(eye development)|go:"GO:0001714"(endodermal cell fate specification)|go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006325"(chromatin organization)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0009611"(response to wounding)|go:"GO:0009653"(anatomical structure morphogenesis)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0021781"(glial cell fate commitment)|go:"GO:0021983"(pituitary gland development)|go:"GO:0021984"(adenohypophysis development)|go:"GO:0022409"(positive regulation of cell-cell adhesion)|go:"GO:0030154"(cell differentiation)|go:"GO:0030900"(forebrain development)|go:"GO:0035019"(somatic stem cell population maintenance)|go:"GO:0035198"(miRNA binding)|go:"GO:0042246"(tissue regeneration)|go:"GO:0043281"(regulation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0043410"(positive regulation of MAPK cascade)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045165"(cell fate commitment)|go:"GO:0045597"(positive regulation of cell differentiation)|go:"GO:0045665"(negative regulation of neuron differentiation)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048839"(inner ear development)|go:"GO:0050680"(negative regulation of epithelial cell proliferation)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0070848"(response to growth factor)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:0097150"(neuronal stem cell population maintenance)|interpro:IPR009071(High mobility group box, HMG)|interpro:IPR022097|interpro:IPR032643|interpro:IPR036910|mint:P48431|rcsb pdb:1O4X|rcsb pdb:2LE4|rcsb pdb:6T7B|rcsb pdb:6T90|rcsb pdb:6WX7|rcsb pdb:6WX8|rcsb pdb:6WX9|rcsb pdb:6YOV|reactome:R-HSA-2892245|reactome:R-HSA-2892247|reactome:R-HSA-3769402|reactome:R-HSA-452723|reactome:R-HSA-6785807|reactome:R-HSA-8986944 refseq:NP_001284673.1|refseq:NP_001107865.1|refseq:NP_001107866.1|refseq:NP_776158.2|refseq:XP_016864642.1|refseq:XP_016864643.1|refseq:XP_016864644.1|refseq:XP_016864645.1|refseq:XP_016864646.1|refseq:XP_016864647.1|refseq:XP_016864648.1|refseq:XP_016864649.1|ensembl:ENSG00000164329(gene)|ensembl:ENST00000296783(transcript)|ensembl:ENST00000428308(transcript)|ensembl:ENST00000453514(transcript)|go:"GO:0002244"(hematopoietic progenitor cell differentiation)|go:"GO:0004652"(polynucleotide adenylyltransferase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005829"(cytosol)|go:"GO:0006378"(mRNA polyadenylation)|go:"GO:0016779"(nucleotidyltransferase activity)|go:"GO:0021766"(hippocampus development)|go:"GO:0030182"(neuron differentiation)|go:"GO:0031123"(RNA 3'-end processing)|go:"GO:0031380"(nuclear RNA-directed RNA polymerase complex)|go:"GO:0034062"(5'-3' RNA polymerase activity)|go:"GO:0043489"(RNA stabilization)|go:"GO:0043631"(RNA polyadenylation)|go:"GO:0046872"(metal ion binding)|go:"GO:0060041"(retina development in camera-type eye)|go:"GO:0070566"(adenylyltransferase activity)|go:"GO:0071044"(histone mRNA catabolic process)|go:"GO:1990603"(dark adaptation)|go:"GO:2000626"(negative regulation of miRNA catabolic process)|interpro:IPR002058(PAP/25A-associated)|interpro:IPR043519|mint:Q6PIY7 go:"GO:0005634"(nucleus) - - figure legend:ST2 F2A|comment:proteins identified only in our induced samples in three MudPIT analyses with the more stringent BY-adjusted significance p<0.05|dataset:Brain Disease - Neurological Diseases & Disorders|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-daoy)|taxid:9606(Homo sapiens DAOY cerebellar medulloblastoma cell line) - 2020/12/29 2020/12/29 rogid:cn8gYfKDpQc8J2ygnqny32sIyyU9606 rogid:QSN7ZKgdCNKeKfYdAou4NXxqNv89606 rigid:6EMs5+B89Q89RCR/2S2BG6PhH9E false tandem tag:n-n - - - psi-mi:"MI:0658"(multidimensional protein identification technology) psi-mi:"MI:0658"(multidimensional protein identification technology) uniprotkb:P48431 uniprotkb:P17535 intact:EBI-6124081|uniprotkb:Q14537|ensembl:ENSP00000323588 intact:EBI-2682803|uniprotkb:Q53EK9|ensembl:ENSP00000252818 psi-mi:sox2_human(display_long)|uniprotkb:SOX2(gene name)|psi-mi:SOX2(display_short) psi-mi:jund_human(display_long)|uniprotkb:JUND(gene name)|psi-mi:JUND(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Cox et al. (2012) pubmed:23667531|imex:IM-28599 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-26574619|imex:IM-28599-5 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_003097.1|dip:DIP-59913N|ensembl:ENSG00000181449(gene)|ensembl:ENST00000325404(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001649"(osteoblast differentiation)|go:"GO:0001654"(eye development)|go:"GO:0001714"(endodermal cell fate specification)|go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006325"(chromatin organization)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0009611"(response to wounding)|go:"GO:0009653"(anatomical structure morphogenesis)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0021781"(glial cell fate commitment)|go:"GO:0021983"(pituitary gland development)|go:"GO:0021984"(adenohypophysis development)|go:"GO:0022409"(positive regulation of cell-cell adhesion)|go:"GO:0030154"(cell differentiation)|go:"GO:0030900"(forebrain development)|go:"GO:0035019"(somatic stem cell population maintenance)|go:"GO:0035198"(miRNA binding)|go:"GO:0042246"(tissue regeneration)|go:"GO:0043281"(regulation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0043410"(positive regulation of MAPK cascade)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045165"(cell fate commitment)|go:"GO:0045597"(positive regulation of cell differentiation)|go:"GO:0045665"(negative regulation of neuron differentiation)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048839"(inner ear development)|go:"GO:0050680"(negative regulation of epithelial cell proliferation)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0070848"(response to growth factor)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:0097150"(neuronal stem cell population maintenance)|interpro:IPR009071(High mobility group box, HMG)|interpro:IPR022097|interpro:IPR032643|interpro:IPR036910|mint:P48431|rcsb pdb:1O4X|rcsb pdb:2LE4|rcsb pdb:6T7B|rcsb pdb:6T90|rcsb pdb:6WX7|rcsb pdb:6WX8|rcsb pdb:6WX9|rcsb pdb:6YOV|reactome:R-HSA-2892245|reactome:R-HSA-2892247|reactome:R-HSA-3769402|reactome:R-HSA-452723|reactome:R-HSA-6785807|reactome:R-HSA-8986944 refseq:NP_001273897.1|refseq:NP_005345.3|ensembl:ENSG00000130522(gene)|go:"GO:0007623"(circadian rhythm)|go:"GO:0009416"(response to light stimulus)|go:"GO:0009612"(response to mechanical stimulus)|go:"GO:0014070"(response to organic cyclic compound)|go:"GO:0016922"(nuclear receptor binding)|go:"GO:0019899"(enzyme binding)|go:"GO:0032496"(response to lipopolysaccharide)|go:"GO:0032993"(protein-DNA complex)|go:"GO:0035976"(transcription factor AP-1 complex)|go:"GO:0042127"(regulation of cell population proliferation)|go:"GO:0043032"(positive regulation of macrophage activation)|ensembl:ENST00000252818(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0043434"(response to peptide hormone)|go:"GO:0045669"(positive regulation of osteoblast differentiation)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0071277"(cellular response to calcium ion)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR002112(Transcription factor Jun)|interpro:IPR004827("Basic-leucine zipper (bZIP) transcription factor")|interpro:IPR005643(Jun-like transcription factor)|interpro:IPR008917(Eukaryotic transcription factor, Skn-1-like, DNA-binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|interpro:IPR029823|mint:P17535|rcsb pdb:3U86|rcsb pdb:5VPA|rcsb pdb:5VPB|rcsb pdb:5VPC|rcsb pdb:5VPD|rcsb pdb:5VPE|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|rcsb pdb:5VPF|reactome:R-HSA-9018519|reactome:R-HSA-9031628|go:"GO:0002076"(osteoblast development)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0007568"(aging)|dip:DIP-1053N go:"GO:0005634"(nucleus) - - figure legend:ST2 F2A|comment:proteins identified only in our induced samples in three MudPIT analyses with the more stringent BY-adjusted significance p<0.05|dataset:Brain Disease - Neurological Diseases & Disorders|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-daoy)|taxid:9606(Homo sapiens DAOY cerebellar medulloblastoma cell line) - 2020/12/29 2020/12/29 rogid:cn8gYfKDpQc8J2ygnqny32sIyyU9606 rogid:npmTGULvlKr4hC8HfmK19GUopf49606 rigid:6EMs5+B89Q89RCR/2S2BG6PhH9E false tandem tag:n-n - - - psi-mi:"MI:0658"(multidimensional protein identification technology) psi-mi:"MI:0658"(multidimensional protein identification technology) uniprotkb:P48431 uniprotkb:Q13418 intact:EBI-6124081|uniprotkb:Q14537|ensembl:ENSP00000323588 intact:EBI-747644|uniprotkb:P57043|uniprotkb:Q68DZ3|uniprotkb:B7Z1I0|uniprotkb:D3DQU0|uniprotkb:B7Z418|ensembl:ENSP00000299421|ensembl:ENSP00000379975|ensembl:ENSP00000403487 psi-mi:sox2_human(display_long)|uniprotkb:SOX2(gene name)|psi-mi:SOX2(display_short) psi-mi:ilk_human(display_long)|uniprotkb:ILK-1(gene name synonym)|uniprotkb:ILK-2(gene name synonym)|uniprotkb:59 kDa serine/threonine-protein kinase(gene name synonym)|uniprotkb:p59ILK(gene name synonym)|uniprotkb:ILK(gene name)|psi-mi:ILK(display_short)|uniprotkb:ILK1(gene name synonym)|uniprotkb:ILK2(gene name synonym)|uniprotkb:Beta-integrin-linked kinase(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Cox et al. (2012) pubmed:23667531|imex:IM-28599 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-26574619|imex:IM-28599-5 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_003097.1|dip:DIP-59913N|ensembl:ENSG00000181449(gene)|ensembl:ENST00000325404(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001649"(osteoblast differentiation)|go:"GO:0001654"(eye development)|go:"GO:0001714"(endodermal cell fate specification)|go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006325"(chromatin organization)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0009611"(response to wounding)|go:"GO:0009653"(anatomical structure morphogenesis)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0021781"(glial cell fate commitment)|go:"GO:0021983"(pituitary gland development)|go:"GO:0021984"(adenohypophysis development)|go:"GO:0022409"(positive regulation of cell-cell adhesion)|go:"GO:0030154"(cell differentiation)|go:"GO:0030900"(forebrain development)|go:"GO:0035019"(somatic stem cell population maintenance)|go:"GO:0035198"(miRNA binding)|go:"GO:0042246"(tissue regeneration)|go:"GO:0043281"(regulation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0043410"(positive regulation of MAPK cascade)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045165"(cell fate commitment)|go:"GO:0045597"(positive regulation of cell differentiation)|go:"GO:0045665"(negative regulation of neuron differentiation)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048839"(inner ear development)|go:"GO:0050680"(negative regulation of epithelial cell proliferation)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0070848"(response to growth factor)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:0097150"(neuronal stem cell population maintenance)|interpro:IPR009071(High mobility group box, HMG)|interpro:IPR022097|interpro:IPR032643|interpro:IPR036910|mint:P48431|rcsb pdb:1O4X|rcsb pdb:2LE4|rcsb pdb:6T7B|rcsb pdb:6T90|rcsb pdb:6WX7|rcsb pdb:6WX8|rcsb pdb:6WX9|rcsb pdb:6YOV|reactome:R-HSA-2892245|reactome:R-HSA-2892247|reactome:R-HSA-3769402|reactome:R-HSA-452723|reactome:R-HSA-6785807|reactome:R-HSA-8986944 refseq:NP_001265370.1|refseq:NP_001014794.1|refseq:NP_001014795.1|refseq:NP_004508.1|refseq:XP_005252961.1|refseq:NP_001265371.1|refseq:XP_005252962.1|refseq:XP_011518367.1|dip:DIP-38657N|rcsb pdb:3IXE|rcsb pdb:3KMU|rcsb pdb:3KMW|rcsb pdb:3REP|rcsb pdb:4HI8|rcsb pdb:4HI9|rcsb pdb:6MIB|reactome:R-HSA-446343|reactome:R-HSA-446353|ensembl:ENSG00000166333(gene)|ensembl:ENST00000299421(transcript)|ensembl:ENST00000396751(transcript)|ensembl:ENST00000420936(transcript)|go:"GO:0000902"(cell morphogenesis)|go:"GO:0001658"(branching involved in ureteric bud morphogenesis)|go:"GO:0001725"(stress fiber)|go:"GO:0001934"(positive regulation of protein phosphorylation)|go:"GO:0003151"(outflow tract morphogenesis)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0001954"(positive regulation of cell-matrix adhesion)|go:"GO:0005178"(integrin binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005925"(focal adhesion)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0006469"(negative regulation of protein kinase activity)|go:"GO:0007160"(cell-matrix adhesion)|go:"GO:0007229"(integrin-mediated signaling pathway)|go:"GO:0007569"(cell aging)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0009967"(positive regulation of signal transduction)|go:"GO:0010667"(negative regulation of cardiac muscle cell apoptotic process)|go:"GO:0010761"(fibroblast migration)|go:"GO:0014912"(negative regulation of smooth muscle cell migration)|go:"GO:0016020"(membrane)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0018105"(peptidyl-serine phosphorylation)|go:"GO:0019901"(protein kinase binding)|go:"GO:0021675"(nerve development)|go:"GO:0022011"(myelination in peripheral nervous system)|go:"GO:0030017"(sarcomere)|go:"GO:0030027"(lamellipodium)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0030513"(positive regulation of BMP signaling pathway)|go:"GO:0032288"(myelin assembly)|go:"GO:0032956"(regulation of actin cytoskeleton organization)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033209"(tumor necrosis factor-mediated signaling pathway)|go:"GO:0034446"(substrate adhesion-dependent cell spreading)|go:"GO:0042327"(positive regulation of phosphorylation)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043034"(costamere)|go:"GO:0043195"(terminal bouton)|go:"GO:0043198"(dendritic shaft)|go:"GO:0043406"(positive regulation of MAP kinase activity)|go:"GO:0043491"(protein kinase B signaling)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0045197"(establishment or maintenance of epithelial cell apical/basal polarity)|go:"GO:0045669"(positive regulation of osteoblast differentiation)|go:"GO:0045773"(positive regulation of axon extension)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0048662"(negative regulation of smooth muscle cell proliferation)|go:"GO:0048812"(neuron projection morphogenesis)|go:"GO:0050775"(positive regulation of dendrite morphogenesis)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0051897"(positive regulation of protein kinase B signaling)|go:"GO:0070527"(platelet aggregation)|go:"GO:0090263"(positive regulation of canonical Wnt signaling pathway)|go:"GO:0097435"(supramolecular fiber organization)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:1900026"(positive regulation of substrate adhesion-dependent cell spreading)|go:"GO:1901224"(positive regulation of NIK/NF-kappaB signaling)|go:"GO:2000178"(negative regulation of neural precursor cell proliferation)|interpro:IPR000719(Protein kinase, core)|interpro:IPR001245(Tyrosine protein kinase)|interpro:IPR002110(Ankyrin)|interpro:IPR011009(Protein kinase-like)|interpro:IPR020683|interpro:IPR035692|interpro:IPR036770|mint:Q13418|rcsb pdb:2KBX|rcsb pdb:3F6Q|go:"GO:0045663"(positive regulation of myoblast differentiation) go:"GO:0005634"(nucleus) - - figure legend:ST2 F2A|comment:proteins identified only in our induced samples in three MudPIT analyses with the more stringent BY-adjusted significance p<0.05|dataset:Brain Disease - Neurological Diseases & Disorders|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-daoy)|taxid:9606(Homo sapiens DAOY cerebellar medulloblastoma cell line) - 2020/12/29 2020/12/29 rogid:cn8gYfKDpQc8J2ygnqny32sIyyU9606 rogid:FrK/MsW7IcVWT9VbkHAIVHEh1P89606 rigid:6EMs5+B89Q89RCR/2S2BG6PhH9E false tandem tag:n-n - - - psi-mi:"MI:0658"(multidimensional protein identification technology) psi-mi:"MI:0658"(multidimensional protein identification technology) uniprotkb:P48431 uniprotkb:Q63HK5 intact:EBI-6124081|uniprotkb:Q14537|ensembl:ENSP00000323588 intact:EBI-9053916|uniprotkb:Q9H0G6|uniprotkb:Q9P254|intact:EBI-10171826|uniprotkb:A1L0U7|ensembl:ENSP00000240587 psi-mi:sox2_human(display_long)|uniprotkb:SOX2(gene name)|psi-mi:SOX2(display_short) psi-mi:tsh3_human(display_long)|uniprotkb:KIAA1474(gene name synonym)|uniprotkb:TSH3(gene name synonym)|uniprotkb:ZNF537(gene name synonym)|uniprotkb:Zinc finger protein 537(gene name synonym)|uniprotkb:TSHZ3(gene name)|psi-mi:TSHZ3(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Cox et al. (2012) pubmed:23667531|imex:IM-28599 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-26574619|imex:IM-28599-5 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_003097.1|dip:DIP-59913N|ensembl:ENSG00000181449(gene)|ensembl:ENST00000325404(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001649"(osteoblast differentiation)|go:"GO:0001654"(eye development)|go:"GO:0001714"(endodermal cell fate specification)|go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006325"(chromatin organization)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0009611"(response to wounding)|go:"GO:0009653"(anatomical structure morphogenesis)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0021781"(glial cell fate commitment)|go:"GO:0021983"(pituitary gland development)|go:"GO:0021984"(adenohypophysis development)|go:"GO:0022409"(positive regulation of cell-cell adhesion)|go:"GO:0030154"(cell differentiation)|go:"GO:0030900"(forebrain development)|go:"GO:0035019"(somatic stem cell population maintenance)|go:"GO:0035198"(miRNA binding)|go:"GO:0042246"(tissue regeneration)|go:"GO:0043281"(regulation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0043410"(positive regulation of MAPK cascade)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045165"(cell fate commitment)|go:"GO:0045597"(positive regulation of cell differentiation)|go:"GO:0045665"(negative regulation of neuron differentiation)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048839"(inner ear development)|go:"GO:0050680"(negative regulation of epithelial cell proliferation)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0070848"(response to growth factor)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:0097150"(neuronal stem cell population maintenance)|interpro:IPR009071(High mobility group box, HMG)|interpro:IPR022097|interpro:IPR032643|interpro:IPR036910|mint:P48431|rcsb pdb:1O4X|rcsb pdb:2LE4|rcsb pdb:6T7B|rcsb pdb:6T90|rcsb pdb:6WX7|rcsb pdb:6WX8|rcsb pdb:6WX9|rcsb pdb:6YOV|reactome:R-HSA-2892245|reactome:R-HSA-2892247|reactome:R-HSA-3769402|reactome:R-HSA-452723|reactome:R-HSA-6785807|reactome:R-HSA-8986944 refseq:NP_065907.2|ensembl:ENSP00000240587|ensembl:ENSG00000121297(gene)|ensembl:ENST00000240587(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0002087"(regulation of respiratory gaseous exchange by nervous system process)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0030426"(growth cone)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0046872"(metal ion binding)|go:"GO:0051968"(positive regulation of synaptic transmission, glutamatergic)|go:"GO:0060291"(long-term synaptic potentiation)|interpro:IPR001356(Homeobox)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR026810|interpro:IPR027008|mint:Q63HK5|rcsb pdb:2DMI go:"GO:0005634"(nucleus) - - figure legend:ST2 F2A|comment:proteins identified only in our induced samples in three MudPIT analyses with the more stringent BY-adjusted significance p<0.05|dataset:Brain Disease - Neurological Diseases & Disorders|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-daoy)|taxid:9606(Homo sapiens DAOY cerebellar medulloblastoma cell line) - 2020/12/29 2020/12/29 rogid:cn8gYfKDpQc8J2ygnqny32sIyyU9606 rogid:LnljEqngBiFz+krUpZZO/N24VkE9606 rigid:6EMs5+B89Q89RCR/2S2BG6PhH9E false tandem tag:n-n - - - psi-mi:"MI:0658"(multidimensional protein identification technology) psi-mi:"MI:0658"(multidimensional protein identification technology) uniprotkb:P48431 uniprotkb:Q9UQ88 intact:EBI-6124081|uniprotkb:Q14537|ensembl:ENSP00000323588 intact:EBI-373024|uniprotkb:O95227|uniprotkb:O95228|uniprotkb:O96012|uniprotkb:Q12821|uniprotkb:Q12853|uniprotkb:Q12854|uniprotkb:Q5QPR0|uniprotkb:Q5QPR1|uniprotkb:Q5QPR2|uniprotkb:Q9UBC4|uniprotkb:Q9UBI3|uniprotkb:Q9UEI1|uniprotkb:Q9UEI2|uniprotkb:Q9UP53|uniprotkb:Q9UP54|uniprotkb:Q9UP55|uniprotkb:Q9UP56|uniprotkb:Q9UQ86|uniprotkb:Q9UQ87|uniprotkb:Q9UQ89|uniprotkb:Q2TAJ0|ensembl:ENSP00000367900 psi-mi:sox2_human(display_long)|uniprotkb:SOX2(gene name)|psi-mi:SOX2(display_short) psi-mi:cd11a_human(display_long)|uniprotkb:CDK11A(gene name)|psi-mi:CDK11A(display_short)|uniprotkb:PITSLREB(gene name synonym)|uniprotkb:Cell division cycle 2-like protein kinase 2(gene name synonym)|uniprotkb:Galactosyltransferase-associated protein kinase p58/GTA(gene name synonym)|uniprotkb:CDC2L2(gene name synonym)|uniprotkb:CDC2L3(gene name synonym)|uniprotkb:PITSLRE serine/threonine-protein kinase CDC2L2(gene name synonym)|uniprotkb:Cell division protein kinase 11A(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Cox et al. (2012) pubmed:23667531|imex:IM-28599 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-26574619|imex:IM-28599-5 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_003097.1|dip:DIP-59913N|ensembl:ENSG00000181449(gene)|ensembl:ENST00000325404(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001649"(osteoblast differentiation)|go:"GO:0001654"(eye development)|go:"GO:0001714"(endodermal cell fate specification)|go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006325"(chromatin organization)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0009611"(response to wounding)|go:"GO:0009653"(anatomical structure morphogenesis)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0021781"(glial cell fate commitment)|go:"GO:0021983"(pituitary gland development)|go:"GO:0021984"(adenohypophysis development)|go:"GO:0022409"(positive regulation of cell-cell adhesion)|go:"GO:0030154"(cell differentiation)|go:"GO:0030900"(forebrain development)|go:"GO:0035019"(somatic stem cell population maintenance)|go:"GO:0035198"(miRNA binding)|go:"GO:0042246"(tissue regeneration)|go:"GO:0043281"(regulation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0043410"(positive regulation of MAPK cascade)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045165"(cell fate commitment)|go:"GO:0045597"(positive regulation of cell differentiation)|go:"GO:0045665"(negative regulation of neuron differentiation)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048839"(inner ear development)|go:"GO:0050680"(negative regulation of epithelial cell proliferation)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0070848"(response to growth factor)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:0097150"(neuronal stem cell population maintenance)|interpro:IPR009071(High mobility group box, HMG)|interpro:IPR022097|interpro:IPR032643|interpro:IPR036910|mint:P48431|rcsb pdb:1O4X|rcsb pdb:2LE4|rcsb pdb:6T7B|rcsb pdb:6T90|rcsb pdb:6WX7|rcsb pdb:6WX8|rcsb pdb:6WX9|rcsb pdb:6YOV|reactome:R-HSA-2892245|reactome:R-HSA-2892247|reactome:R-HSA-3769402|reactome:R-HSA-452723|reactome:R-HSA-6785807|reactome:R-HSA-8986944 refseq:NP_076916.2|refseq:NP_277071.2|refseq:NP_001300825.1|refseq:NP_001300911.1|ensembl:ENSG00000008128(gene)|ensembl:ENST00000378633(transcript)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0001558"(regulation of cell growth)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0004693"(cyclin-dependent protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0006915"(apoptotic process)|go:"GO:0007346"(regulation of mitotic cell cycle)|go:"GO:0050684"(regulation of mRNA processing)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|mint:Q9UQ88|reactome:R-HSA-380270 go:"GO:0005634"(nucleus) - - figure legend:ST2 F2A|comment:proteins identified only in our induced samples in three MudPIT analyses with the more stringent BY-adjusted significance p<0.05|dataset:Brain Disease - Neurological Diseases & Disorders|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-daoy)|taxid:9606(Homo sapiens DAOY cerebellar medulloblastoma cell line) - 2020/12/29 2020/12/29 rogid:cn8gYfKDpQc8J2ygnqny32sIyyU9606 rogid:h30ee1oqCuzFkWhpX9dsmJFl9Y09606 rigid:6EMs5+B89Q89RCR/2S2BG6PhH9E false tandem tag:n-n - - - psi-mi:"MI:0658"(multidimensional protein identification technology) psi-mi:"MI:0658"(multidimensional protein identification technology) uniprotkb:P48431 uniprotkb:Q68E01 intact:EBI-6124081|uniprotkb:Q14537|ensembl:ENSP00000323588 intact:EBI-2680854|uniprotkb:Q8TB23|uniprotkb:Q6MZQ4|uniprotkb:Q9H6S9|uniprotkb:Q6AI57|uniprotkb:Q5VUQ6|uniprotkb:Q4G0E5|uniprotkb:B4DQC8|uniprotkb:B4E3U9|uniprotkb:A8K1W0|uniprotkb:Q8NC46|uniprotkb:Q68DJ1|uniprotkb:Q6DKG7|uniprotkb:Q5VUR1|uniprotkb:Q6MZZ9|uniprotkb:Q5VUQ5|uniprotkb:Q69YR5|uniprotkb:Q5VUR0|uniprotkb:D3DV57 psi-mi:sox2_human(display_long)|uniprotkb:SOX2(gene name)|psi-mi:SOX2(display_short) psi-mi:int3_human(display_long)|uniprotkb:INTS3(gene name)|psi-mi:INTS3(display_short)|uniprotkb:C1orf193(gene name synonym)|uniprotkb:C1orf60(gene name synonym)|uniprotkb:SOSS complex subunit A(gene name synonym)|uniprotkb:Sensor of single-strand DNA complex subunit A(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Cox et al. (2012) pubmed:23667531|imex:IM-28599 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-26574619|imex:IM-28599-5 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_003097.1|dip:DIP-59913N|ensembl:ENSG00000181449(gene)|ensembl:ENST00000325404(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001649"(osteoblast differentiation)|go:"GO:0001654"(eye development)|go:"GO:0001714"(endodermal cell fate specification)|go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006325"(chromatin organization)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0009611"(response to wounding)|go:"GO:0009653"(anatomical structure morphogenesis)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0021781"(glial cell fate commitment)|go:"GO:0021983"(pituitary gland development)|go:"GO:0021984"(adenohypophysis development)|go:"GO:0022409"(positive regulation of cell-cell adhesion)|go:"GO:0030154"(cell differentiation)|go:"GO:0030900"(forebrain development)|go:"GO:0035019"(somatic stem cell population maintenance)|go:"GO:0035198"(miRNA binding)|go:"GO:0042246"(tissue regeneration)|go:"GO:0043281"(regulation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0043410"(positive regulation of MAPK cascade)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045165"(cell fate commitment)|go:"GO:0045597"(positive regulation of cell differentiation)|go:"GO:0045665"(negative regulation of neuron differentiation)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048839"(inner ear development)|go:"GO:0050680"(negative regulation of epithelial cell proliferation)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0070848"(response to growth factor)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:0097150"(neuronal stem cell population maintenance)|interpro:IPR009071(High mobility group box, HMG)|interpro:IPR022097|interpro:IPR032643|interpro:IPR036910|mint:P48431|rcsb pdb:1O4X|rcsb pdb:2LE4|rcsb pdb:6T7B|rcsb pdb:6T90|rcsb pdb:6WX7|rcsb pdb:6WX8|rcsb pdb:6WX9|rcsb pdb:6YOV|reactome:R-HSA-2892245|reactome:R-HSA-2892247|reactome:R-HSA-3769402|reactome:R-HSA-452723|reactome:R-HSA-6785807|reactome:R-HSA-8986944 refseq:NP_075391.3|interpro:IPR019333|refseq:XP_005245518.1|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006281"(DNA repair)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0010212"(response to ionizing radiation)|go:"GO:0016180"(snRNA processing)|go:"GO:0032039"(integrator complex)|go:"GO:0035861"(site of double-strand break)|go:"GO:0044818"(mitotic G2/M transition checkpoint)|go:"GO:0070876"(SOSS complex)|rcsb pdb:4OWT|rcsb pdb:4OWW|rcsb pdb:4OWX|rcsb pdb:6WLG|reactome:R-HSA-6807505|refseq:NP_001311404.1|mint:Q68E01 go:"GO:0005634"(nucleus) - - figure legend:ST2 F2A|comment:proteins identified only in our induced samples in three MudPIT analyses with the more stringent BY-adjusted significance p<0.05|dataset:Brain Disease - Neurological Diseases & Disorders|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-daoy)|taxid:9606(Homo sapiens DAOY cerebellar medulloblastoma cell line) - 2020/12/29 2020/12/29 rogid:cn8gYfKDpQc8J2ygnqny32sIyyU9606 rogid:GxQTTVSOwBdWifr7ZdM8Zbqxy5M9606 rigid:6EMs5+B89Q89RCR/2S2BG6PhH9E false tandem tag:n-n - - - psi-mi:"MI:0658"(multidimensional protein identification technology) psi-mi:"MI:0658"(multidimensional protein identification technology) uniprotkb:P48431 uniprotkb:Q14781 intact:EBI-6124081|uniprotkb:Q14537|ensembl:ENSP00000323588 intact:EBI-745934|uniprotkb:Q9BTB1|uniprotkb:Q0VDA5|ensembl:ENSP00000308750 psi-mi:sox2_human(display_long)|uniprotkb:SOX2(gene name)|psi-mi:SOX2(display_short) psi-mi:cbx2_human(display_long)|uniprotkb:CBX2(gene name)|psi-mi:CBX2(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Cox et al. (2012) pubmed:23667531|imex:IM-28599 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-26574619|imex:IM-28599-5 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_003097.1|dip:DIP-59913N|ensembl:ENSG00000181449(gene)|ensembl:ENST00000325404(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001649"(osteoblast differentiation)|go:"GO:0001654"(eye development)|go:"GO:0001714"(endodermal cell fate specification)|go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006325"(chromatin organization)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0009611"(response to wounding)|go:"GO:0009653"(anatomical structure morphogenesis)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0021781"(glial cell fate commitment)|go:"GO:0021983"(pituitary gland development)|go:"GO:0021984"(adenohypophysis development)|go:"GO:0022409"(positive regulation of cell-cell adhesion)|go:"GO:0030154"(cell differentiation)|go:"GO:0030900"(forebrain development)|go:"GO:0035019"(somatic stem cell population maintenance)|go:"GO:0035198"(miRNA binding)|go:"GO:0042246"(tissue regeneration)|go:"GO:0043281"(regulation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0043410"(positive regulation of MAPK cascade)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045165"(cell fate commitment)|go:"GO:0045597"(positive regulation of cell differentiation)|go:"GO:0045665"(negative regulation of neuron differentiation)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048839"(inner ear development)|go:"GO:0050680"(negative regulation of epithelial cell proliferation)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0070848"(response to growth factor)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:0097150"(neuronal stem cell population maintenance)|interpro:IPR009071(High mobility group box, HMG)|interpro:IPR022097|interpro:IPR032643|interpro:IPR036910|mint:P48431|rcsb pdb:1O4X|rcsb pdb:2LE4|rcsb pdb:6T7B|rcsb pdb:6T90|rcsb pdb:6WX7|rcsb pdb:6WX8|rcsb pdb:6WX9|rcsb pdb:6YOV|reactome:R-HSA-2892245|reactome:R-HSA-2892247|reactome:R-HSA-3769402|reactome:R-HSA-452723|reactome:R-HSA-6785807|reactome:R-HSA-8986944 refseq:NP_005180.1|refseq:NP_116036.1|interpro:IPR000953(Chromo domain)|interpro:IPR016197(Chromo domain-like)|interpro:IPR023779|interpro:IPR023780|interpro:IPR033773|go:"GO:0045137"(development of primary sexual characteristics)|interpro:IPR042796|mint:Q14781|rcsb pdb:2D9U|rcsb pdb:3H91|rcsb pdb:5EPK|reactome:R-HSA-2559580|reactome:R-HSA-3108214|reactome:R-HSA-3899300|reactome:R-HSA-4551638|reactome:R-HSA-4570464|reactome:R-HSA-4655427|reactome:R-HSA-8939243|reactome:R-HSA-8943724|ensembl:ENSG00000173894(gene)|ensembl:ENST00000310942(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000791"(euchromatin)|go:"GO:0000792"(heterochromatin)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006325"(chromatin organization)|go:"GO:0030154"(cell differentiation)|go:"GO:0031519"(PcG protein complex)|go:"GO:0035064"(methylated histone binding)|go:"GO:0035102"(PRC1 complex)|dip:DIP-48604N go:"GO:0005634"(nucleus) - - figure legend:ST2 F2A|comment:proteins identified only in our induced samples in three MudPIT analyses with the more stringent BY-adjusted significance p<0.05|dataset:Brain Disease - Neurological Diseases & Disorders|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-daoy)|taxid:9606(Homo sapiens DAOY cerebellar medulloblastoma cell line) - 2020/12/29 2020/12/29 rogid:cn8gYfKDpQc8J2ygnqny32sIyyU9606 rogid:220eC8UGlmAHHP2WAhZdAveHC3s9606 rigid:6EMs5+B89Q89RCR/2S2BG6PhH9E false tandem tag:n-n - - - psi-mi:"MI:0658"(multidimensional protein identification technology) psi-mi:"MI:0658"(multidimensional protein identification technology) uniprotkb:P48431 uniprotkb:Q9BR76 intact:EBI-6124081|uniprotkb:Q14537|ensembl:ENSP00000323588 intact:EBI-351152|uniprotkb:B2RD45|ensembl:ENSP00000340211|ensembl:ENSP00000377471 psi-mi:sox2_human(display_long)|uniprotkb:SOX2(gene name)|psi-mi:SOX2(display_short) psi-mi:cor1b_human(display_long)|uniprotkb:CORO1B(gene name)|psi-mi:CORO1B(display_short)|uniprotkb:Coronin-2(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Cox et al. (2012) pubmed:23667531|imex:IM-28599 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-26574619|imex:IM-28599-5 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_003097.1|dip:DIP-59913N|ensembl:ENSG00000181449(gene)|ensembl:ENST00000325404(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001649"(osteoblast differentiation)|go:"GO:0001654"(eye development)|go:"GO:0001714"(endodermal cell fate specification)|go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006325"(chromatin organization)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0009611"(response to wounding)|go:"GO:0009653"(anatomical structure morphogenesis)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0021781"(glial cell fate commitment)|go:"GO:0021983"(pituitary gland development)|go:"GO:0021984"(adenohypophysis development)|go:"GO:0022409"(positive regulation of cell-cell adhesion)|go:"GO:0030154"(cell differentiation)|go:"GO:0030900"(forebrain development)|go:"GO:0035019"(somatic stem cell population maintenance)|go:"GO:0035198"(miRNA binding)|go:"GO:0042246"(tissue regeneration)|go:"GO:0043281"(regulation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0043410"(positive regulation of MAPK cascade)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045165"(cell fate commitment)|go:"GO:0045597"(positive regulation of cell differentiation)|go:"GO:0045665"(negative regulation of neuron differentiation)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048839"(inner ear development)|go:"GO:0050680"(negative regulation of epithelial cell proliferation)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0070848"(response to growth factor)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:0097150"(neuronal stem cell population maintenance)|interpro:IPR009071(High mobility group box, HMG)|interpro:IPR022097|interpro:IPR032643|interpro:IPR036910|mint:P48431|rcsb pdb:1O4X|rcsb pdb:2LE4|rcsb pdb:6T7B|rcsb pdb:6T90|rcsb pdb:6WX7|rcsb pdb:6WX8|rcsb pdb:6WX9|rcsb pdb:6YOV|reactome:R-HSA-2892245|reactome:R-HSA-2892247|reactome:R-HSA-3769402|reactome:R-HSA-452723|reactome:R-HSA-6785807|reactome:R-HSA-8986944 refseq:NP_001018080.1|refseq:NP_065174.1|ensembl:ENSG00000172725(gene)|ensembl:ENST00000341356(transcript)|ensembl:ENST00000393893(transcript)|go:"GO:0001725"(stress fiber)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005884"(actin filament)|go:"GO:0005886"(plasma membrane)|go:"GO:0005925"(focal adhesion)|go:"GO:0007015"(actin filament organization)|go:"GO:0016477"(cell migration)|go:"GO:0030027"(lamellipodium)|go:"GO:0030036"(actin cytoskeleton organization)|go:"GO:0031252"(cell leading edge)|go:"GO:0031529"(ruffle organization)|go:"GO:0034315"(regulation of Arp2/3 complex-mediated actin nucleation)|go:"GO:0034316"(negative regulation of Arp2/3 complex-mediated actin nucleation)|go:"GO:0036120"(cellular response to platelet-derived growth factor stimulus)|go:"GO:0042060"(wound healing)|go:"GO:0042802"(identical protein binding)|go:"GO:0045296"(cadherin binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051015"(actin filament binding)|go:"GO:0051017"(actin filament bundle assembly)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071672"(negative regulation of smooth muscle cell chemotaxis)|go:"GO:0071933"(Arp2/3 complex binding)|go:"GO:0071944"(cell periphery)|go:"GO:0090135"(actin filament branching)|go:"GO:1902463"(protein localization to cell leading edge)|go:"GO:2000394"(positive regulation of lamellipodium morphogenesis)|interpro:IPR001680(WD40 repeat)|interpro:IPR015048(Region of unknown function DUF1899)|interpro:IPR015505(Coronin)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019775|interpro:IPR027340|interpro:IPR036322|mint:Q9BR76|go:"GO:0035767"(endothelial cell chemotaxis)|dip:DIP-33176N go:"GO:0005634"(nucleus) - - figure legend:ST2 F2A|comment:proteins identified only in our induced samples in three MudPIT analyses with the more stringent BY-adjusted significance p<0.05|dataset:Brain Disease - Neurological Diseases & Disorders|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-daoy)|taxid:9606(Homo sapiens DAOY cerebellar medulloblastoma cell line) - 2020/12/29 2020/12/29 rogid:cn8gYfKDpQc8J2ygnqny32sIyyU9606 rogid:80hrtgIbLoisOZLGgfaa1TLBFMg9606 rigid:6EMs5+B89Q89RCR/2S2BG6PhH9E false tandem tag:n-n - - - psi-mi:"MI:0658"(multidimensional protein identification technology) psi-mi:"MI:0658"(multidimensional protein identification technology) uniprotkb:P48431 uniprotkb:Q68DK7 intact:EBI-6124081|uniprotkb:Q14537|ensembl:ENSP00000323588 intact:EBI-2560816|ensembl:ENSP00000381543|uniprotkb:Q69Z03|uniprotkb:Q0VF46|intact:EBI-2654071 psi-mi:sox2_human(display_long)|uniprotkb:SOX2(gene name)|psi-mi:SOX2(display_short) psi-mi:msl1_human(display_long)|uniprotkb:MSL1(gene name)|psi-mi:MSL1(display_short)|uniprotkb:MSL1L1(gene name synonym)|uniprotkb:Male-specific lethal 1-like 1(gene name synonym)|uniprotkb:Male-specific lethal-1 homolog 1(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Cox et al. (2012) pubmed:23667531|imex:IM-28599 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-26574619|imex:IM-28599-5 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_003097.1|dip:DIP-59913N|ensembl:ENSG00000181449(gene)|ensembl:ENST00000325404(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001649"(osteoblast differentiation)|go:"GO:0001654"(eye development)|go:"GO:0001714"(endodermal cell fate specification)|go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006325"(chromatin organization)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0009611"(response to wounding)|go:"GO:0009653"(anatomical structure morphogenesis)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0021781"(glial cell fate commitment)|go:"GO:0021983"(pituitary gland development)|go:"GO:0021984"(adenohypophysis development)|go:"GO:0022409"(positive regulation of cell-cell adhesion)|go:"GO:0030154"(cell differentiation)|go:"GO:0030900"(forebrain development)|go:"GO:0035019"(somatic stem cell population maintenance)|go:"GO:0035198"(miRNA binding)|go:"GO:0042246"(tissue regeneration)|go:"GO:0043281"(regulation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0043410"(positive regulation of MAPK cascade)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045165"(cell fate commitment)|go:"GO:0045597"(positive regulation of cell differentiation)|go:"GO:0045665"(negative regulation of neuron differentiation)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048839"(inner ear development)|go:"GO:0050680"(negative regulation of epithelial cell proliferation)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0070848"(response to growth factor)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:0097150"(neuronal stem cell population maintenance)|interpro:IPR009071(High mobility group box, HMG)|interpro:IPR022097|interpro:IPR032643|interpro:IPR036910|mint:P48431|rcsb pdb:1O4X|rcsb pdb:2LE4|rcsb pdb:6T7B|rcsb pdb:6T90|rcsb pdb:6WX7|rcsb pdb:6WX8|rcsb pdb:6WX9|rcsb pdb:6YOV|reactome:R-HSA-2892245|reactome:R-HSA-2892247|reactome:R-HSA-3769402|reactome:R-HSA-452723|reactome:R-HSA-6785807|reactome:R-HSA-8986944 ensembl:ENSG00000188895(gene)|ensembl:ENST00000398532(transcript)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0016607"(nuclear speck)|go:"GO:0043984"(histone H4-K16 acetylation)|go:"GO:0072487"(MSL complex)|interpro:IPR026711|interpro:IPR029332|interpro:IPR031840|mint:Q68DK7|rcsb pdb:4B7Y|rcsb pdb:4B86|rcsb pdb:4DNC|reactome:R-HSA-3214847|refseq:NP_001012241.1|refseq:XP_005257355.1|dip:DIP-56862N go:"GO:0005634"(nucleus) - - figure legend:ST2 F2A|comment:proteins identified only in our induced samples in three MudPIT analyses with the more stringent BY-adjusted significance p<0.05|dataset:Brain Disease - Neurological Diseases & Disorders|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-daoy)|taxid:9606(Homo sapiens DAOY cerebellar medulloblastoma cell line) - 2020/12/29 2020/12/29 rogid:cn8gYfKDpQc8J2ygnqny32sIyyU9606 rogid:sFenPEZNoGtpn1bDFoUzSJBPUBY9606 rigid:6EMs5+B89Q89RCR/2S2BG6PhH9E false tandem tag:n-n - - - psi-mi:"MI:0658"(multidimensional protein identification technology) psi-mi:"MI:0658"(multidimensional protein identification technology) uniprotkb:P48431 uniprotkb:Q08AF3 intact:EBI-6124081|uniprotkb:Q14537|ensembl:ENSP00000323588 intact:EBI-2822593|uniprotkb:Q8WU54|uniprotkb:Q08AF2|uniprotkb:Q96A82|ensembl:ENSP00000299977 psi-mi:sox2_human(display_long)|uniprotkb:SOX2(gene name)|psi-mi:SOX2(display_short) psi-mi:slfn5_human(display_long)|uniprotkb:SLFN5(gene name)|psi-mi:SLFN5(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Cox et al. (2012) pubmed:23667531|imex:IM-28599 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-26574619|imex:IM-28599-5 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_003097.1|dip:DIP-59913N|ensembl:ENSG00000181449(gene)|ensembl:ENST00000325404(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001649"(osteoblast differentiation)|go:"GO:0001654"(eye development)|go:"GO:0001714"(endodermal cell fate specification)|go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006325"(chromatin organization)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0009611"(response to wounding)|go:"GO:0009653"(anatomical structure morphogenesis)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0021781"(glial cell fate commitment)|go:"GO:0021983"(pituitary gland development)|go:"GO:0021984"(adenohypophysis development)|go:"GO:0022409"(positive regulation of cell-cell adhesion)|go:"GO:0030154"(cell differentiation)|go:"GO:0030900"(forebrain development)|go:"GO:0035019"(somatic stem cell population maintenance)|go:"GO:0035198"(miRNA binding)|go:"GO:0042246"(tissue regeneration)|go:"GO:0043281"(regulation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0043410"(positive regulation of MAPK cascade)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045165"(cell fate commitment)|go:"GO:0045597"(positive regulation of cell differentiation)|go:"GO:0045665"(negative regulation of neuron differentiation)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048839"(inner ear development)|go:"GO:0050680"(negative regulation of epithelial cell proliferation)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0070848"(response to growth factor)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:0097150"(neuronal stem cell population maintenance)|interpro:IPR009071(High mobility group box, HMG)|interpro:IPR022097|interpro:IPR032643|interpro:IPR036910|mint:P48431|rcsb pdb:1O4X|rcsb pdb:2LE4|rcsb pdb:6T7B|rcsb pdb:6T90|rcsb pdb:6WX7|rcsb pdb:6WX8|rcsb pdb:6WX9|rcsb pdb:6YOV|reactome:R-HSA-2892245|reactome:R-HSA-2892247|reactome:R-HSA-3769402|reactome:R-HSA-452723|reactome:R-HSA-6785807|reactome:R-HSA-8986944 refseq:NP_659412.3|ensembl:ENSG00000166750(gene)|ensembl:ENST00000299977(transcript)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0030154"(cell differentiation)|interpro:IPR007421(ATPase associated with various cellular activities, AAA-4)|interpro:IPR018647|interpro:IPR027417|interpro:IPR029671|interpro:IPR029684|interpro:IPR038461|rcsb pdb:6RR9|mint:Q08AF3 go:"GO:0005634"(nucleus) - - figure legend:ST2 F2A|comment:proteins identified only in our induced samples in three MudPIT analyses with the more stringent BY-adjusted significance p<0.05|dataset:Brain Disease - Neurological Diseases & Disorders|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-daoy)|taxid:9606(Homo sapiens DAOY cerebellar medulloblastoma cell line) - 2020/12/29 2020/12/29 rogid:cn8gYfKDpQc8J2ygnqny32sIyyU9606 rogid:+BZzuyp+fqb1tLg86wpHu/5RPMI9606 rigid:6EMs5+B89Q89RCR/2S2BG6PhH9E false tandem tag:n-n - - - psi-mi:"MI:0658"(multidimensional protein identification technology) psi-mi:"MI:0658"(multidimensional protein identification technology) uniprotkb:P48431 uniprotkb:Q15528 intact:EBI-6124081|uniprotkb:Q14537|ensembl:ENSP00000323588 intact:EBI-394687|uniprotkb:Q5T8U0|uniprotkb:O76072|uniprotkb:B3KW83|uniprotkb:B3KWX4|ensembl:ENSP00000342343|ensembl:ENSP00000482438|ensembl:ENSP00000485880|ensembl:ENSP00000487580 psi-mi:sox2_human(display_long)|uniprotkb:SOX2(gene name)|psi-mi:SOX2(display_short) psi-mi:med22_human(display_long)|uniprotkb:Mediator complex subunit 22(gene name synonym)|uniprotkb:MED22(gene name)|psi-mi:MED22(display_short)|uniprotkb:Surfeit locus protein 5(gene name synonym)|uniprotkb:SURF5(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Cox et al. (2012) pubmed:23667531|imex:IM-28599 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-26574619|imex:IM-28599-5 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_003097.1|dip:DIP-59913N|ensembl:ENSG00000181449(gene)|ensembl:ENST00000325404(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001649"(osteoblast differentiation)|go:"GO:0001654"(eye development)|go:"GO:0001714"(endodermal cell fate specification)|go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006325"(chromatin organization)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0009611"(response to wounding)|go:"GO:0009653"(anatomical structure morphogenesis)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0021781"(glial cell fate commitment)|go:"GO:0021983"(pituitary gland development)|go:"GO:0021984"(adenohypophysis development)|go:"GO:0022409"(positive regulation of cell-cell adhesion)|go:"GO:0030154"(cell differentiation)|go:"GO:0030900"(forebrain development)|go:"GO:0035019"(somatic stem cell population maintenance)|go:"GO:0035198"(miRNA binding)|go:"GO:0042246"(tissue regeneration)|go:"GO:0043281"(regulation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0043410"(positive regulation of MAPK cascade)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045165"(cell fate commitment)|go:"GO:0045597"(positive regulation of cell differentiation)|go:"GO:0045665"(negative regulation of neuron differentiation)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048839"(inner ear development)|go:"GO:0050680"(negative regulation of epithelial cell proliferation)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0070848"(response to growth factor)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:0097150"(neuronal stem cell population maintenance)|interpro:IPR009071(High mobility group box, HMG)|interpro:IPR022097|interpro:IPR032643|interpro:IPR036910|mint:P48431|rcsb pdb:1O4X|rcsb pdb:2LE4|rcsb pdb:6T7B|rcsb pdb:6T90|rcsb pdb:6WX7|rcsb pdb:6WX8|rcsb pdb:6WX9|rcsb pdb:6YOV|reactome:R-HSA-2892245|reactome:R-HSA-2892247|reactome:R-HSA-3769402|reactome:R-HSA-452723|reactome:R-HSA-6785807|reactome:R-HSA-8986944 refseq:NP_598395.1|refseq:NP_852468.1|ensembl:ENSG00000148297(gene)|ensembl:ENSG00000281022(gene)|ensembl:ENST00000343730(transcript)|ensembl:ENST00000610672(transcript)|ensembl:ENST00000629522(transcript)|ensembl:ENST00000631196(transcript)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0016592"(mediator complex)|interpro:IPR009332(Surfeit locus 5)|mint:Q15528|rcsb pdb:7EMF|rcsb pdb:7ENA|rcsb pdb:7ENC|rcsb pdb:7ENJ|rcsb pdb:7LBM|rcsb pdb:7NVR|reactome:R-HSA-1989781|reactome:R-HSA-381340 go:"GO:0005634"(nucleus) - - figure legend:ST2 F2A|comment:proteins identified only in our induced samples in three MudPIT analyses with the more stringent BY-adjusted significance p<0.05|dataset:Brain Disease - Neurological Diseases & Disorders|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-daoy)|taxid:9606(Homo sapiens DAOY cerebellar medulloblastoma cell line) - 2020/12/29 2020/12/29 rogid:cn8gYfKDpQc8J2ygnqny32sIyyU9606 rogid:bAtK0Srk81ujvVt2Gj0+py7RCZY9606 rigid:6EMs5+B89Q89RCR/2S2BG6PhH9E false tandem tag:n-n - - - psi-mi:"MI:0658"(multidimensional protein identification technology) psi-mi:"MI:0658"(multidimensional protein identification technology) uniprotkb:P48431 uniprotkb:Q9NU22 intact:EBI-6124081|uniprotkb:Q14537|ensembl:ENSP00000323588 intact:EBI-1050480|uniprotkb:O15019|uniprotkb:Q5T794|ensembl:ENSP00000358400|ensembl:ENSP00000486270|ensembl:ENSP00000499843|ensembl:ENSP00000499895 psi-mi:sox2_human(display_long)|uniprotkb:SOX2(gene name)|psi-mi:SOX2(display_short) psi-mi:mdn1_human(display_long)|uniprotkb:MIDAS-containing protein(gene name synonym)|uniprotkb:Dynein-related AAA-ATPase MDN1(gene name synonym)|uniprotkb:MDN1(gene name)|psi-mi:MDN1(display_short)|uniprotkb:KIAA0301(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Cox et al. (2012) pubmed:23667531|imex:IM-28599 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-26574619|imex:IM-28599-5 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_003097.1|dip:DIP-59913N|ensembl:ENSG00000181449(gene)|ensembl:ENST00000325404(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001649"(osteoblast differentiation)|go:"GO:0001654"(eye development)|go:"GO:0001714"(endodermal cell fate specification)|go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006325"(chromatin organization)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0009611"(response to wounding)|go:"GO:0009653"(anatomical structure morphogenesis)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0021781"(glial cell fate commitment)|go:"GO:0021983"(pituitary gland development)|go:"GO:0021984"(adenohypophysis development)|go:"GO:0022409"(positive regulation of cell-cell adhesion)|go:"GO:0030154"(cell differentiation)|go:"GO:0030900"(forebrain development)|go:"GO:0035019"(somatic stem cell population maintenance)|go:"GO:0035198"(miRNA binding)|go:"GO:0042246"(tissue regeneration)|go:"GO:0043281"(regulation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0043410"(positive regulation of MAPK cascade)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045165"(cell fate commitment)|go:"GO:0045597"(positive regulation of cell differentiation)|go:"GO:0045665"(negative regulation of neuron differentiation)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048839"(inner ear development)|go:"GO:0050680"(negative regulation of epithelial cell proliferation)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0070848"(response to growth factor)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:0097150"(neuronal stem cell population maintenance)|interpro:IPR009071(High mobility group box, HMG)|interpro:IPR022097|interpro:IPR032643|interpro:IPR036910|mint:P48431|rcsb pdb:1O4X|rcsb pdb:2LE4|rcsb pdb:6T7B|rcsb pdb:6T90|rcsb pdb:6WX7|rcsb pdb:6WX8|rcsb pdb:6WX9|rcsb pdb:6YOV|reactome:R-HSA-2892245|reactome:R-HSA-2892247|reactome:R-HSA-3769402|reactome:R-HSA-452723|reactome:R-HSA-6785807|reactome:R-HSA-8986944 refseq:NP_055426.1|ensembl:ENSG00000112159(gene)|ensembl:ENSG00000288121(gene)|ensembl:ENST00000369393(transcript)|ensembl:ENST00000629399(transcript)|ensembl:ENST00000672983(transcript)|ensembl:ENST00000673332(transcript)|go:"GO:0000027"(ribosomal large subunit assembly)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0006364"(rRNA processing)|go:"GO:0016020"(membrane)|go:"GO:0016887"(ATP hydrolysis activity)|go:"GO:0030687"(preribosome, large subunit precursor)|go:"GO:0045111"(intermediate filament cytoskeleton)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0065003"(protein-containing complex assembly)|interpro:IPR002035(von Willebrand factor, type A)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR011704(ATPase associated with various cellular activities, AAA-5)|interpro:IPR012099(Midasin)|interpro:IPR027417|interpro:IPR036465|interpro:IPR040848|interpro:IPR041190|mint:Q9NU22|go:"GO:0005829"(cytosol) go:"GO:0005634"(nucleus) - - figure legend:ST2 F2A|comment:proteins identified only in our induced samples in three MudPIT analyses with the more stringent BY-adjusted significance p<0.05|dataset:Brain Disease - Neurological Diseases & Disorders|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-daoy)|taxid:9606(Homo sapiens DAOY cerebellar medulloblastoma cell line) - 2020/12/29 2020/12/29 rogid:cn8gYfKDpQc8J2ygnqny32sIyyU9606 rogid:/LVYhffZVpP0pYVM6hLNltoc6pY9606 rigid:6EMs5+B89Q89RCR/2S2BG6PhH9E false tandem tag:n-n - - - psi-mi:"MI:0658"(multidimensional protein identification technology) psi-mi:"MI:0658"(multidimensional protein identification technology) uniprotkb:P48431 uniprotkb:Q96SY0 intact:EBI-6124081|uniprotkb:Q14537|ensembl:ENSP00000323588 intact:EBI-4409724|uniprotkb:Q49AH8|uniprotkb:Q96HX5|uniprotkb:Q9H0S5|uniprotkb:B4DDI6|uniprotkb:B4DVD5|ensembl:ENSP00000326379 psi-mi:sox2_human(display_long)|uniprotkb:SOX2(gene name)|psi-mi:SOX2(display_short) psi-mi:int14_human(display_long)|uniprotkb:VWA9(gene name synonym)|uniprotkb:INTS14(gene name)|psi-mi:INTS14(display_short)|uniprotkb:C15orf44(gene name synonym)|uniprotkb:von Willebrand factor A domain-containing protein 9(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Cox et al. (2012) pubmed:23667531|imex:IM-28599 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-26574619|imex:IM-28599-5 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_003097.1|dip:DIP-59913N|ensembl:ENSG00000181449(gene)|ensembl:ENST00000325404(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001649"(osteoblast differentiation)|go:"GO:0001654"(eye development)|go:"GO:0001714"(endodermal cell fate specification)|go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006325"(chromatin organization)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0009611"(response to wounding)|go:"GO:0009653"(anatomical structure morphogenesis)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0021781"(glial cell fate commitment)|go:"GO:0021983"(pituitary gland development)|go:"GO:0021984"(adenohypophysis development)|go:"GO:0022409"(positive regulation of cell-cell adhesion)|go:"GO:0030154"(cell differentiation)|go:"GO:0030900"(forebrain development)|go:"GO:0035019"(somatic stem cell population maintenance)|go:"GO:0035198"(miRNA binding)|go:"GO:0042246"(tissue regeneration)|go:"GO:0043281"(regulation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0043410"(positive regulation of MAPK cascade)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045165"(cell fate commitment)|go:"GO:0045597"(positive regulation of cell differentiation)|go:"GO:0045665"(negative regulation of neuron differentiation)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048839"(inner ear development)|go:"GO:0050680"(negative regulation of epithelial cell proliferation)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0070848"(response to growth factor)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:0097150"(neuronal stem cell population maintenance)|interpro:IPR009071(High mobility group box, HMG)|interpro:IPR022097|interpro:IPR032643|interpro:IPR036910|mint:P48431|rcsb pdb:1O4X|rcsb pdb:2LE4|rcsb pdb:6T7B|rcsb pdb:6T90|rcsb pdb:6WX7|rcsb pdb:6WX8|rcsb pdb:6WX9|rcsb pdb:6YOV|reactome:R-HSA-2892245|reactome:R-HSA-2892247|reactome:R-HSA-3769402|reactome:R-HSA-452723|reactome:R-HSA-6785807|reactome:R-HSA-8986944 refseq:NP_001129515.1|refseq:XP_011520403.1|refseq:NP_001193987.1|refseq:NP_001193988.1|refseq:XP_006720772.1|refseq:XP_006720774.1|refseq:XP_016878133.1|ensembl:ENSG00000138614(gene)|ensembl:ENST00000313182(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0032039"(integrator complex)|go:"GO:0034472"(snRNA 3'-end processing)|interpro:IPR002035(von Willebrand factor, type A)|interpro:IPR036465|interpro:IPR039841|mint:Q96SY0|rcsb pdb:6SN1|reactome:R-HSA-6807505 go:"GO:0005634"(nucleus) - - figure legend:ST2 F2A|comment:proteins identified only in our induced samples in three MudPIT analyses with the more stringent BY-adjusted significance p<0.05|dataset:Brain Disease - Neurological Diseases & Disorders|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-daoy)|taxid:9606(Homo sapiens DAOY cerebellar medulloblastoma cell line) - 2020/12/29 2020/12/29 rogid:cn8gYfKDpQc8J2ygnqny32sIyyU9606 rogid:a1H+KgPggyxgI/jQfUR68x6X8iI9606 rigid:6EMs5+B89Q89RCR/2S2BG6PhH9E false tandem tag:n-n - - - psi-mi:"MI:0658"(multidimensional protein identification technology) psi-mi:"MI:0658"(multidimensional protein identification technology) uniprotkb:P48431 uniprotkb:Q9Y2Q9 intact:EBI-6124081|uniprotkb:Q14537|ensembl:ENSP00000323588 intact:EBI-5325249|ensembl:ENSP00000276585|uniprotkb:B2RDZ7|uniprotkb:Q96Q21 psi-mi:sox2_human(display_long)|uniprotkb:SOX2(gene name)|psi-mi:SOX2(display_short) psi-mi:rt28_human(display_long)|uniprotkb:Mitochondrial small ribosomal subunit protein bS1m(gene name synonym)|uniprotkb:HSPC007(orf name)|uniprotkb:MRPS28(gene name)|psi-mi:MRPS28(display_short)|uniprotkb:MRPS35(gene name synonym)|uniprotkb:28S ribosomal protein S35, mitochondrial(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Cox et al. (2012) pubmed:23667531|imex:IM-28599 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-26574619|imex:IM-28599-5 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_003097.1|dip:DIP-59913N|ensembl:ENSG00000181449(gene)|ensembl:ENST00000325404(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001649"(osteoblast differentiation)|go:"GO:0001654"(eye development)|go:"GO:0001714"(endodermal cell fate specification)|go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006325"(chromatin organization)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0009611"(response to wounding)|go:"GO:0009653"(anatomical structure morphogenesis)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0021781"(glial cell fate commitment)|go:"GO:0021983"(pituitary gland development)|go:"GO:0021984"(adenohypophysis development)|go:"GO:0022409"(positive regulation of cell-cell adhesion)|go:"GO:0030154"(cell differentiation)|go:"GO:0030900"(forebrain development)|go:"GO:0035019"(somatic stem cell population maintenance)|go:"GO:0035198"(miRNA binding)|go:"GO:0042246"(tissue regeneration)|go:"GO:0043281"(regulation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0043410"(positive regulation of MAPK cascade)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045165"(cell fate commitment)|go:"GO:0045597"(positive regulation of cell differentiation)|go:"GO:0045665"(negative regulation of neuron differentiation)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048839"(inner ear development)|go:"GO:0050680"(negative regulation of epithelial cell proliferation)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0070848"(response to growth factor)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:0097150"(neuronal stem cell population maintenance)|interpro:IPR009071(High mobility group box, HMG)|interpro:IPR022097|interpro:IPR032643|interpro:IPR036910|mint:P48431|rcsb pdb:1O4X|rcsb pdb:2LE4|rcsb pdb:6T7B|rcsb pdb:6T90|rcsb pdb:6WX7|rcsb pdb:6WX8|rcsb pdb:6WX9|rcsb pdb:6YOV|reactome:R-HSA-2892245|reactome:R-HSA-2892247|reactome:R-HSA-3769402|reactome:R-HSA-452723|reactome:R-HSA-6785807|reactome:R-HSA-8986944 ensembl:ENST00000276585(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005763"(mitochondrial small ribosomal subunit)|go:"GO:0032543"(mitochondrial translation)|interpro:IPR019375|mint:Q9Y2Q9|rcsb pdb:3J9M|rcsb pdb:6NU2|rcsb pdb:6NU3|rcsb pdb:6RW4|rcsb pdb:6RW5|rcsb pdb:6VLZ|rcsb pdb:6VMI|rcsb pdb:6ZM5|rcsb pdb:6ZM6|rcsb pdb:6ZS9|rcsb pdb:6ZSA|rcsb pdb:6ZSB|rcsb pdb:6ZSC|rcsb pdb:6ZSD|rcsb pdb:6ZSE|rcsb pdb:6ZSG|rcsb pdb:7A5F|rcsb pdb:7A5G|rcsb pdb:7A5I|ensembl:ENSG00000147586(gene)|rcsb pdb:7A5K|rcsb pdb:7L08|rcsb pdb:7OG4|reactome:R-HSA-5368286|reactome:R-HSA-5389840|reactome:R-HSA-5419276|refseq:NP_054737.1 go:"GO:0005634"(nucleus) - - figure legend:ST2 F2A|comment:proteins identified only in our induced samples in three MudPIT analyses with the more stringent BY-adjusted significance p<0.05|dataset:Brain Disease - Neurological Diseases & Disorders|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-daoy)|taxid:9606(Homo sapiens DAOY cerebellar medulloblastoma cell line) - 2020/12/29 2020/12/29 rogid:cn8gYfKDpQc8J2ygnqny32sIyyU9606 rogid:E78l52n5CxYuz9U1JoMSG5jJjMA9606 rigid:6EMs5+B89Q89RCR/2S2BG6PhH9E false tandem tag:n-n - - - psi-mi:"MI:0658"(multidimensional protein identification technology) psi-mi:"MI:0658"(multidimensional protein identification technology) uniprotkb:P48431 uniprotkb:P27708 intact:EBI-6124081|uniprotkb:Q14537|ensembl:ENSP00000323588 intact:EBI-355504|uniprotkb:Q6P0Q0|uniprotkb:D6W552|ensembl:ENSP00000264705|uniprotkb:Q96CK3 psi-mi:sox2_human(display_long)|uniprotkb:SOX2(gene name)|psi-mi:SOX2(display_short) psi-mi:pyr1_human(display_long)|uniprotkb:CAD(gene name)|psi-mi:CAD(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Cox et al. (2012) pubmed:23667531|imex:IM-28599 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-26574619|imex:IM-28599-5 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_003097.1|dip:DIP-59913N|ensembl:ENSG00000181449(gene)|ensembl:ENST00000325404(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001649"(osteoblast differentiation)|go:"GO:0001654"(eye development)|go:"GO:0001714"(endodermal cell fate specification)|go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006325"(chromatin organization)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0009611"(response to wounding)|go:"GO:0009653"(anatomical structure morphogenesis)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0021781"(glial cell fate commitment)|go:"GO:0021983"(pituitary gland development)|go:"GO:0021984"(adenohypophysis development)|go:"GO:0022409"(positive regulation of cell-cell adhesion)|go:"GO:0030154"(cell differentiation)|go:"GO:0030900"(forebrain development)|go:"GO:0035019"(somatic stem cell population maintenance)|go:"GO:0035198"(miRNA binding)|go:"GO:0042246"(tissue regeneration)|go:"GO:0043281"(regulation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0043410"(positive regulation of MAPK cascade)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045165"(cell fate commitment)|go:"GO:0045597"(positive regulation of cell differentiation)|go:"GO:0045665"(negative regulation of neuron differentiation)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048839"(inner ear development)|go:"GO:0050680"(negative regulation of epithelial cell proliferation)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0070848"(response to growth factor)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:0097150"(neuronal stem cell population maintenance)|interpro:IPR009071(High mobility group box, HMG)|interpro:IPR022097|interpro:IPR032643|interpro:IPR036910|mint:P48431|rcsb pdb:1O4X|rcsb pdb:2LE4|rcsb pdb:6T7B|rcsb pdb:6T90|rcsb pdb:6WX7|rcsb pdb:6WX8|rcsb pdb:6WX9|rcsb pdb:6YOV|reactome:R-HSA-2892245|reactome:R-HSA-2892247|reactome:R-HSA-3769402|reactome:R-HSA-452723|reactome:R-HSA-6785807|reactome:R-HSA-8986944 refseq:NP_004332.2|ensembl:ENSG00000084774(gene)|ensembl:ENST00000264705(transcript)|go:"GO:0001889"(liver development)|go:"GO:0004070"(aspartate carbamoyltransferase activity)|go:"GO:0004088"("carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity")|go:"GO:0004151"(dihydroorotase activity)|go:"GO:0004672"(protein kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006207"('de novo' pyrimidine nucleobase biosynthetic process)|go:"GO:0006228"(UTP biosynthetic process)|go:"GO:0006541"(glutamine metabolic process)|go:"GO:0006807"(nitrogen compound metabolic process)|go:"GO:0007507"(heart development)|go:"GO:0007565"(female pregnancy)|go:"GO:0007595"(lactation)|go:"GO:0008270"(zinc ion binding)|go:"GO:0014075"(response to amine)|go:"GO:0016363"(nuclear matrix)|go:"GO:0017144"|go:"GO:0018107"(peptidyl-threonine phosphorylation)|go:"GO:0019240"(citrulline biosynthetic process)|go:"GO:0019899"(enzyme binding)|go:"GO:0031000"(response to caffeine)|go:"GO:0031100"(animal organ regeneration)|go:"GO:0032868"(response to insulin)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033574"(response to testosterone)|go:"GO:0035690"|go:"GO:0042594"(response to starvation)|go:"GO:0042802"(identical protein binding)|go:"GO:0042995"(cell projection)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043195"(terminal bouton)|go:"GO:0044205"('de novo' UMP biosynthetic process)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0051414"(response to cortisol)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070335"(aspartate binding)|go:"GO:0071364"(cellular response to epidermal growth factor stimulus)|interpro:IPR002082(Aspartate carbamoyltransferase, eukaryotic)|interpro:IPR002195(Dihydroorotase, conserved site)|interpro:IPR002474(Carbamoyl phosphate synthase, small subunit, N-terminal)|interpro:IPR005479(Carbamoyl phosphate synthetase, large subunit, ATP-binding)|interpro:IPR005480(Carbamoyl phosphate synthetase, large subunit, oligomerisation)|interpro:IPR005483(Carbamoyl phosphate synthase, large subunit)|interpro:IPR006130(Aspartate/ornithine carbamoyltransferase)|interpro:IPR006131(Aspartate/ornithine carbamoyltransferase, Asp/Orn-binding region)|interpro:IPR006132(Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding)|interpro:IPR006274(Carbamoyl phosphate synthase, small subunit)|interpro:IPR006275(Carbamoyl phosphate synthase, large subunit, glutamine-dependent)|interpro:IPR006680(Amidohydrolase 1)|interpro:IPR011059(Metal-dependent hydrolase, composite)|interpro:IPR011607(MGS-like)|interpro:IPR011761(ATP-grasp fold)|interpro:IPR013815(ATP-grasp fold, subdomain 1)|interpro:IPR016185(PreATP-grasp-like fold)|interpro:IPR017926|interpro:IPR029062|interpro:IPR032466|interpro:IPR035686|interpro:IPR036480|interpro:IPR036897|interpro:IPR036901|interpro:IPR036914|mint:P27708|go:"GO:0016020"(membrane)|rcsb pdb:4BY3|rcsb pdb:4C6B|rcsb pdb:4C6C|rcsb pdb:4C6D|rcsb pdb:4C6E|rcsb pdb:4C6F|rcsb pdb:4C6I|rcsb pdb:4C6J|rcsb pdb:4C6K|rcsb pdb:4C6L|rcsb pdb:4C6M|rcsb pdb:4C6N|rcsb pdb:4C6O|rcsb pdb:4C6P|rcsb pdb:4C6Q|rcsb pdb:5G1N|rcsb pdb:5G1O|rcsb pdb:5G1P|rcsb pdb:5YNZ|rcsb pdb:6HFD|rcsb pdb:6HFE|rcsb pdb:6HFF|rcsb pdb:6HFH|rcsb pdb:6HFI|rcsb pdb:6HFJ|rcsb pdb:6HFK|rcsb pdb:6HFL|rcsb pdb:6HFP|rcsb pdb:6HFQ|rcsb pdb:6HFR|rcsb pdb:6HFS|rcsb pdb:6HFU|rcsb pdb:6HG1|reactome:R-HSA-500753|rcsb pdb:6HFN|refseq:NP_001293008.1|dip:DIP-39484N go:"GO:0005634"(nucleus) - - figure legend:ST2 F2A|comment:proteins identified only in our induced samples in three MudPIT analyses with the more stringent BY-adjusted significance p<0.05|dataset:Brain Disease - Neurological Diseases & Disorders|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-daoy)|taxid:9606(Homo sapiens DAOY cerebellar medulloblastoma cell line) - 2020/12/29 2020/12/29 rogid:cn8gYfKDpQc8J2ygnqny32sIyyU9606 rogid:m5iR4BQz6t2dbQxtP1MARVW0LAw9606 rigid:6EMs5+B89Q89RCR/2S2BG6PhH9E false tandem tag:n-n - - - psi-mi:"MI:0658"(multidimensional protein identification technology) psi-mi:"MI:0658"(multidimensional protein identification technology) uniprotkb:P48431 uniprotkb:Q9BYD6 intact:EBI-6124081|uniprotkb:Q14537|ensembl:ENSP00000323588 intact:EBI-5325394|ensembl:ENSP00000315017|uniprotkb:A6NG03|uniprotkb:Q4W5B8|uniprotkb:Q6IAG4|uniprotkb:Q96BW3|uniprotkb:Q9H793|uniprotkb:Q9NRL5 psi-mi:sox2_human(display_long)|uniprotkb:SOX2(gene name)|psi-mi:SOX2(display_short) psi-mi:rm01_human(display_long)|uniprotkb:Mitochondrial large ribosomal subunit protein uL1m(gene name synonym)|uniprotkb:BM-022(orf name)|uniprotkb:MRPL1(gene name)|psi-mi:MRPL1(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Cox et al. (2012) pubmed:23667531|imex:IM-28599 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-26574619|imex:IM-28599-5 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_003097.1|dip:DIP-59913N|ensembl:ENSG00000181449(gene)|ensembl:ENST00000325404(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001649"(osteoblast differentiation)|go:"GO:0001654"(eye development)|go:"GO:0001714"(endodermal cell fate specification)|go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006325"(chromatin organization)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0009611"(response to wounding)|go:"GO:0009653"(anatomical structure morphogenesis)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0021781"(glial cell fate commitment)|go:"GO:0021983"(pituitary gland development)|go:"GO:0021984"(adenohypophysis development)|go:"GO:0022409"(positive regulation of cell-cell adhesion)|go:"GO:0030154"(cell differentiation)|go:"GO:0030900"(forebrain development)|go:"GO:0035019"(somatic stem cell population maintenance)|go:"GO:0035198"(miRNA binding)|go:"GO:0042246"(tissue regeneration)|go:"GO:0043281"(regulation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0043410"(positive regulation of MAPK cascade)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045165"(cell fate commitment)|go:"GO:0045597"(positive regulation of cell differentiation)|go:"GO:0045665"(negative regulation of neuron differentiation)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048839"(inner ear development)|go:"GO:0050680"(negative regulation of epithelial cell proliferation)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0070848"(response to growth factor)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:0097150"(neuronal stem cell population maintenance)|interpro:IPR009071(High mobility group box, HMG)|interpro:IPR022097|interpro:IPR032643|interpro:IPR036910|mint:P48431|rcsb pdb:1O4X|rcsb pdb:2LE4|rcsb pdb:6T7B|rcsb pdb:6T90|rcsb pdb:6WX7|rcsb pdb:6WX8|rcsb pdb:6WX9|rcsb pdb:6YOV|reactome:R-HSA-2892245|reactome:R-HSA-2892247|reactome:R-HSA-3769402|reactome:R-HSA-452723|reactome:R-HSA-6785807|reactome:R-HSA-8986944 ensembl:ENSG00000169288(gene)|ensembl:ENST00000315567(transcript)|go:"GO:0000470"(maturation of LSU-rRNA)|go:"GO:0003723"(RNA binding)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0006412"(translation)|go:"GO:0022625"(cytosolic large ribosomal subunit)|interpro:IPR005879(Ribosomal protein L1, mitochondrial)|interpro:IPR016095(Ribosomal protein L1, 3-layer alpha/beta-sandwich)|interpro:IPR023674|interpro:IPR028364|mint:Q9BYD6|rcsb pdb:7A5K|reactome:R-HSA-5368286|reactome:R-HSA-5389840|reactome:R-HSA-5419276|refseq:XP_011530500.1|refseq:XP_011530501.1|refseq:NP_064621.3 go:"GO:0005634"(nucleus) - - figure legend:ST2 F2A|comment:proteins identified only in our induced samples in three MudPIT analyses with the more stringent BY-adjusted significance p<0.05|dataset:Brain Disease - Neurological Diseases & Disorders|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-daoy)|taxid:9606(Homo sapiens DAOY cerebellar medulloblastoma cell line) - 2020/12/29 2020/12/29 rogid:cn8gYfKDpQc8J2ygnqny32sIyyU9606 rogid:S5t4UAM2nDToXMl6lV3gh6Ecef09606 rigid:6EMs5+B89Q89RCR/2S2BG6PhH9E false tandem tag:n-n - - - psi-mi:"MI:0658"(multidimensional protein identification technology) psi-mi:"MI:0658"(multidimensional protein identification technology) uniprotkb:P48431 uniprotkb:Q9UNF1 intact:EBI-6124081|uniprotkb:Q14537|ensembl:ENSP00000323588 intact:EBI-725832|uniprotkb:O76058|uniprotkb:Q5BJF3|uniprotkb:Q8NAL6|uniprotkb:Q9H218|uniprotkb:Q9P0U9|uniprotkb:A6NMX0|uniprotkb:Q9UM52|ensembl:ENSP00000218439|ensembl:ENSP00000364193|ensembl:ENSP00000364198|ensembl:ENSP00000364209|ensembl:ENSP00000379526 psi-mi:sox2_human(display_long)|uniprotkb:SOX2(gene name)|psi-mi:SOX2(display_short) psi-mi:magd2_human(display_long)|uniprotkb:MAGE-D2 antigen(gene name synonym)|uniprotkb:Breast cancer-associated gene 1 protein(gene name synonym)|uniprotkb:11B6(gene name synonym)|uniprotkb:Hepatocellular carcinoma-associated protein JCL-1(gene name synonym)|uniprotkb:MAGED2(gene name)|psi-mi:MAGED2(display_short)|uniprotkb:BCG1(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Cox et al. (2012) pubmed:23667531|imex:IM-28599 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-26574619|imex:IM-28599-5 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_003097.1|dip:DIP-59913N|ensembl:ENSG00000181449(gene)|ensembl:ENST00000325404(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001649"(osteoblast differentiation)|go:"GO:0001654"(eye development)|go:"GO:0001714"(endodermal cell fate specification)|go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006325"(chromatin organization)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0009611"(response to wounding)|go:"GO:0009653"(anatomical structure morphogenesis)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0021781"(glial cell fate commitment)|go:"GO:0021983"(pituitary gland development)|go:"GO:0021984"(adenohypophysis development)|go:"GO:0022409"(positive regulation of cell-cell adhesion)|go:"GO:0030154"(cell differentiation)|go:"GO:0030900"(forebrain development)|go:"GO:0035019"(somatic stem cell population maintenance)|go:"GO:0035198"(miRNA binding)|go:"GO:0042246"(tissue regeneration)|go:"GO:0043281"(regulation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0043410"(positive regulation of MAPK cascade)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045165"(cell fate commitment)|go:"GO:0045597"(positive regulation of cell differentiation)|go:"GO:0045665"(negative regulation of neuron differentiation)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048839"(inner ear development)|go:"GO:0050680"(negative regulation of epithelial cell proliferation)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0070848"(response to growth factor)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:0097150"(neuronal stem cell population maintenance)|interpro:IPR009071(High mobility group box, HMG)|interpro:IPR022097|interpro:IPR032643|interpro:IPR036910|mint:P48431|rcsb pdb:1O4X|rcsb pdb:2LE4|rcsb pdb:6T7B|rcsb pdb:6T90|rcsb pdb:6WX7|rcsb pdb:6WX8|rcsb pdb:6WX9|rcsb pdb:6YOV|reactome:R-HSA-2892245|reactome:R-HSA-2892247|reactome:R-HSA-3769402|reactome:R-HSA-452723|reactome:R-HSA-6785807|reactome:R-HSA-8986944 refseq:NP_055414.2|refseq:NP_803182.1|refseq:NP_957516.1|ensembl:ENSG00000102316(gene)|ensembl:ENST00000218439(transcript)|ensembl:ENST00000375053(transcript)|ensembl:ENST00000375058(transcript)|ensembl:ENST00000375068(transcript)|ensembl:ENST00000396224(transcript)|go:"GO:0005576"(extracellular region)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0007565"(female pregnancy)|go:"GO:0016020"(membrane)|go:"GO:0031093"(platelet alpha granule lumen)|go:"GO:0070294"(renal sodium ion absorption)|interpro:IPR002190(MAGE protein)|interpro:IPR028810|interpro:IPR037445|interpro:IPR041898|interpro:IPR041899|mint:Q9UNF1|reactome:R-HSA-114608|dip:DIP-50722N go:"GO:0005634"(nucleus) - - figure legend:ST2 F2A|comment:proteins identified only in our induced samples in three MudPIT analyses with the more stringent BY-adjusted significance p<0.05|dataset:Brain Disease - Neurological Diseases & Disorders|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-daoy)|taxid:9606(Homo sapiens DAOY cerebellar medulloblastoma cell line) - 2020/12/29 2020/12/29 rogid:cn8gYfKDpQc8J2ygnqny32sIyyU9606 rogid:fXavezmKy58aGuVgzvDYjwNw3B89606 rigid:6EMs5+B89Q89RCR/2S2BG6PhH9E false tandem tag:n-n - - - psi-mi:"MI:0658"(multidimensional protein identification technology) psi-mi:"MI:0658"(multidimensional protein identification technology) uniprotkb:P48431 uniprotkb:Q96AX1 intact:EBI-6124081|uniprotkb:Q14537|ensembl:ENSP00000323588 intact:EBI-2527283|uniprotkb:Q547V4|uniprotkb:Q9H5Q0|ensembl:ENSP00000267199 psi-mi:sox2_human(display_long)|uniprotkb:SOX2(gene name)|psi-mi:SOX2(display_short) psi-mi:vp33a_human(display_long)|uniprotkb:VPS33A(gene name)|psi-mi:VPS33A(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Cox et al. (2012) pubmed:23667531|imex:IM-28599 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-26574619|imex:IM-28599-5 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_003097.1|dip:DIP-59913N|ensembl:ENSG00000181449(gene)|ensembl:ENST00000325404(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001649"(osteoblast differentiation)|go:"GO:0001654"(eye development)|go:"GO:0001714"(endodermal cell fate specification)|go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006325"(chromatin organization)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0009611"(response to wounding)|go:"GO:0009653"(anatomical structure morphogenesis)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0021781"(glial cell fate commitment)|go:"GO:0021983"(pituitary gland development)|go:"GO:0021984"(adenohypophysis development)|go:"GO:0022409"(positive regulation of cell-cell adhesion)|go:"GO:0030154"(cell differentiation)|go:"GO:0030900"(forebrain development)|go:"GO:0035019"(somatic stem cell population maintenance)|go:"GO:0035198"(miRNA binding)|go:"GO:0042246"(tissue regeneration)|go:"GO:0043281"(regulation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0043410"(positive regulation of MAPK cascade)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045165"(cell fate commitment)|go:"GO:0045597"(positive regulation of cell differentiation)|go:"GO:0045665"(negative regulation of neuron differentiation)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048839"(inner ear development)|go:"GO:0050680"(negative regulation of epithelial cell proliferation)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0070848"(response to growth factor)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:0097150"(neuronal stem cell population maintenance)|interpro:IPR009071(High mobility group box, HMG)|interpro:IPR022097|interpro:IPR032643|interpro:IPR036910|mint:P48431|rcsb pdb:1O4X|rcsb pdb:2LE4|rcsb pdb:6T7B|rcsb pdb:6T90|rcsb pdb:6WX7|rcsb pdb:6WX8|rcsb pdb:6WX9|rcsb pdb:6YOV|reactome:R-HSA-2892245|reactome:R-HSA-2892247|reactome:R-HSA-3769402|reactome:R-HSA-452723|reactome:R-HSA-6785807|reactome:R-HSA-8986944 ensembl:ENSG00000139719(gene)|ensembl:ENST00000267199(transcript)|go:"GO:0005764"(lysosome)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005769"(early endosome)|go:"GO:0005770"(late endosome)|go:"GO:0005773"(vacuole)|go:"GO:0005776"(autophagosome)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0008333"(endosome to lysosome transport)|go:"GO:0016192"(vesicle-mediated transport)|go:"GO:0030136"(clathrin-coated vesicle)|go:"GO:0030220"(platelet formation)|go:"GO:0030897"(HOPS complex)|go:"GO:0032400"(melanosome localization)|go:"GO:0032418"(lysosome localization)|go:"GO:0033263"(CORVET complex)|go:"GO:0035751"(regulation of lysosomal lumen pH)|go:"GO:0048070"(regulation of developmental pigmentation)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0097352"(autophagosome maturation)|interpro:IPR001619(Sec1-like protein)|interpro:IPR027121|interpro:IPR027482|interpro:IPR036045|interpro:IPR043127|interpro:IPR043154|interpro:IPR043155|mint:Q96AX1|rcsb pdb:4BX8|rcsb pdb:4BX9|go:"GO:0031902"(late endosome membrane)|refseq:NP_075067.2 go:"GO:0005634"(nucleus) - - figure legend:ST2 F2A|comment:proteins identified only in our induced samples in three MudPIT analyses with the more stringent BY-adjusted significance p<0.05|dataset:Brain Disease - Neurological Diseases & Disorders|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-daoy)|taxid:9606(Homo sapiens DAOY cerebellar medulloblastoma cell line) - 2020/12/29 2020/12/29 rogid:cn8gYfKDpQc8J2ygnqny32sIyyU9606 rogid:dtPjiiMZ60tlBdhBPrYBHkXAUpE9606 rigid:6EMs5+B89Q89RCR/2S2BG6PhH9E false tandem tag:n-n - - - psi-mi:"MI:0658"(multidimensional protein identification technology) psi-mi:"MI:0658"(multidimensional protein identification technology) uniprotkb:P48431 uniprotkb:O60942 intact:EBI-6124081|uniprotkb:Q14537|ensembl:ENSP00000323588 intact:EBI-1237132|uniprotkb:O43483|uniprotkb:O60257|uniprotkb:O60351|uniprotkb:Q5TCW8|uniprotkb:Q8WUM8|uniprotkb:E1P513|uniprotkb:E1P514|ensembl:ENSP00000358497 psi-mi:sox2_human(display_long)|uniprotkb:SOX2(gene name)|psi-mi:SOX2(display_short) psi-mi:mce1_human(display_long)|uniprotkb:RNGTT(gene name)|psi-mi:RNGTT(display_short)|uniprotkb:CAP1A(gene name synonym)|uniprotkb:HCE(gene name synonym)|uniprotkb:HCAP1(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Cox et al. (2012) pubmed:23667531|imex:IM-28599 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-26574619|imex:IM-28599-5 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_003097.1|dip:DIP-59913N|ensembl:ENSG00000181449(gene)|ensembl:ENST00000325404(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001649"(osteoblast differentiation)|go:"GO:0001654"(eye development)|go:"GO:0001714"(endodermal cell fate specification)|go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006325"(chromatin organization)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0009611"(response to wounding)|go:"GO:0009653"(anatomical structure morphogenesis)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0021781"(glial cell fate commitment)|go:"GO:0021983"(pituitary gland development)|go:"GO:0021984"(adenohypophysis development)|go:"GO:0022409"(positive regulation of cell-cell adhesion)|go:"GO:0030154"(cell differentiation)|go:"GO:0030900"(forebrain development)|go:"GO:0035019"(somatic stem cell population maintenance)|go:"GO:0035198"(miRNA binding)|go:"GO:0042246"(tissue regeneration)|go:"GO:0043281"(regulation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0043410"(positive regulation of MAPK cascade)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045165"(cell fate commitment)|go:"GO:0045597"(positive regulation of cell differentiation)|go:"GO:0045665"(negative regulation of neuron differentiation)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048839"(inner ear development)|go:"GO:0050680"(negative regulation of epithelial cell proliferation)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0070848"(response to growth factor)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:0097150"(neuronal stem cell population maintenance)|interpro:IPR009071(High mobility group box, HMG)|interpro:IPR022097|interpro:IPR032643|interpro:IPR036910|mint:P48431|rcsb pdb:1O4X|rcsb pdb:2LE4|rcsb pdb:6T7B|rcsb pdb:6T90|rcsb pdb:6WX7|rcsb pdb:6WX8|rcsb pdb:6WX9|rcsb pdb:6YOV|reactome:R-HSA-2892245|reactome:R-HSA-2892247|reactome:R-HSA-3769402|reactome:R-HSA-452723|reactome:R-HSA-6785807|reactome:R-HSA-8986944 refseq:NP_001273355.1|refseq:NP_001273357.1|refseq:NP_003791.3|dip:DIP-61014N|ensembl:ENSG00000111880(gene)|ensembl:ENST00000369485(transcript)|go:"GO:0004484"(mRNA guanylyltransferase activity)|go:"GO:0004651"(polynucleotide 5'-phosphatase activity)|go:"GO:0004725"(protein tyrosine phosphatase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006370"(7-methylguanosine mRNA capping)|go:"GO:0006396"(RNA processing)|go:"GO:0008192"(RNA guanylyltransferase activity)|go:"GO:0050355"(triphosphatase activity)|interpro:IPR000340(Protein-tyrosine phosphatase, dual specificity)|interpro:IPR000387(Protein-tyrosine phosphatase)|interpro:IPR001339(mRNA capping enzyme)|interpro:IPR012340(Nucleic acid-binding, OB-fold)|interpro:IPR013846(mRNA capping enzyme, C-terminal)|interpro:IPR016130(Protein-tyrosine phosphatase, active site)|interpro:IPR017074(mRNA capping enzyme, bifunctional)|interpro:IPR020422|interpro:IPR029021|mint:O60942|rcsb pdb:2C46|rcsb pdb:3S24|reactome:R-HSA-167160|reactome:R-HSA-72086|reactome:R-HSA-77075 go:"GO:0005634"(nucleus) - - figure legend:ST2 F2A|comment:proteins identified only in our induced samples in three MudPIT analyses with the more stringent BY-adjusted significance p<0.05|dataset:Brain Disease - Neurological Diseases & Disorders|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-daoy)|taxid:9606(Homo sapiens DAOY cerebellar medulloblastoma cell line) - 2020/12/29 2020/12/29 rogid:cn8gYfKDpQc8J2ygnqny32sIyyU9606 rogid:xiqdXQd75dIqosHNWDCIs1ORyJQ9606 rigid:6EMs5+B89Q89RCR/2S2BG6PhH9E false tandem tag:n-n - - - psi-mi:"MI:0658"(multidimensional protein identification technology) psi-mi:"MI:0658"(multidimensional protein identification technology) uniprotkb:P48431 uniprotkb:P41162 intact:EBI-6124081|uniprotkb:Q14537|ensembl:ENSP00000323588 intact:EBI-3893166|uniprotkb:Q8TAC8|uniprotkb:Q9BX30|uniprotkb:B4E3M7|ensembl:ENSP00000357175 psi-mi:sox2_human(display_long)|uniprotkb:SOX2(gene name)|psi-mi:SOX2(display_short) psi-mi:etv3_human(display_long)|uniprotkb:ETV3(gene name)|psi-mi:ETV3(display_short)|uniprotkb:METS(gene name synonym)|uniprotkb:PE1(gene name synonym)|uniprotkb:ETS domain transcriptional repressor PE1(gene name synonym)|uniprotkb:Mitogenic Ets transcriptional suppressor(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Cox et al. (2012) pubmed:23667531|imex:IM-28599 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-26574619|imex:IM-28599-5 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_003097.1|dip:DIP-59913N|ensembl:ENSG00000181449(gene)|ensembl:ENST00000325404(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001649"(osteoblast differentiation)|go:"GO:0001654"(eye development)|go:"GO:0001714"(endodermal cell fate specification)|go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006325"(chromatin organization)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0009611"(response to wounding)|go:"GO:0009653"(anatomical structure morphogenesis)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0021781"(glial cell fate commitment)|go:"GO:0021983"(pituitary gland development)|go:"GO:0021984"(adenohypophysis development)|go:"GO:0022409"(positive regulation of cell-cell adhesion)|go:"GO:0030154"(cell differentiation)|go:"GO:0030900"(forebrain development)|go:"GO:0035019"(somatic stem cell population maintenance)|go:"GO:0035198"(miRNA binding)|go:"GO:0042246"(tissue regeneration)|go:"GO:0043281"(regulation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0043410"(positive regulation of MAPK cascade)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045165"(cell fate commitment)|go:"GO:0045597"(positive regulation of cell differentiation)|go:"GO:0045665"(negative regulation of neuron differentiation)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048839"(inner ear development)|go:"GO:0050680"(negative regulation of epithelial cell proliferation)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0070848"(response to growth factor)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:0097150"(neuronal stem cell population maintenance)|interpro:IPR009071(High mobility group box, HMG)|interpro:IPR022097|interpro:IPR032643|interpro:IPR036910|mint:P48431|rcsb pdb:1O4X|rcsb pdb:2LE4|rcsb pdb:6T7B|rcsb pdb:6T90|rcsb pdb:6WX7|rcsb pdb:6WX8|rcsb pdb:6WX9|rcsb pdb:6YOV|reactome:R-HSA-2892245|reactome:R-HSA-2892247|reactome:R-HSA-3769402|reactome:R-HSA-452723|reactome:R-HSA-6785807|reactome:R-HSA-8986944 refseq:XP_006711273.1|refseq:NP_001138784.1|refseq:NP_005231.1|ensembl:ENSG00000117036(gene)|ensembl:ENST00000368192(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0017151"(DEAD/H-box RNA helicase binding)|go:"GO:0030154"(cell differentiation)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0090571"(RNA polymerase II transcription repressor complex)|go:"GO:0097011"(cellular response to granulocyte macrophage colony-stimulating factor stimulus)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR032929|interpro:IPR036388|interpro:IPR036390|mint:P41162|interpro:IPR000418(Ets) go:"GO:0005634"(nucleus) - - figure legend:ST2 F2A|comment:proteins identified only in our induced samples in three MudPIT analyses with the more stringent BY-adjusted significance p<0.05|dataset:Brain Disease - Neurological Diseases & Disorders|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-daoy)|taxid:9606(Homo sapiens DAOY cerebellar medulloblastoma cell line) - 2020/12/29 2020/12/29 rogid:cn8gYfKDpQc8J2ygnqny32sIyyU9606 rogid:0SQGr0/nixNUCUOzAEe9bDT+hLM9606 rigid:6EMs5+B89Q89RCR/2S2BG6PhH9E false tandem tag:n-n - - - psi-mi:"MI:0658"(multidimensional protein identification technology) psi-mi:"MI:0658"(multidimensional protein identification technology) uniprotkb:P48431 uniprotkb:Q8N5Y2 intact:EBI-6124081|uniprotkb:Q14537|ensembl:ENSP00000323588 intact:EBI-2560796|ensembl:ENSP00000312244|uniprotkb:Q9Y5Z8|uniprotkb:Q9UG70|uniprotkb:B7Z227|uniprotkb:B4DUV8|uniprotkb:A6NCU2|uniprotkb:A6NHW8|uniprotkb:A8K165 psi-mi:sox2_human(display_long)|uniprotkb:SOX2(gene name)|psi-mi:SOX2(display_short) psi-mi:ms3l1_human(display_long)|uniprotkb:MSL3(gene name)|psi-mi:MSL3(display_short)|uniprotkb:MSL3L1(gene name synonym)|uniprotkb:Male-specific lethal-3 protein-like 1(gene name synonym)|uniprotkb:Male-specific lethal-3 homolog 1(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Cox et al. (2012) pubmed:23667531|imex:IM-28599 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-26574619|imex:IM-28599-5 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_003097.1|dip:DIP-59913N|ensembl:ENSG00000181449(gene)|ensembl:ENST00000325404(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001649"(osteoblast differentiation)|go:"GO:0001654"(eye development)|go:"GO:0001714"(endodermal cell fate specification)|go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006325"(chromatin organization)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0009611"(response to wounding)|go:"GO:0009653"(anatomical structure morphogenesis)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0021781"(glial cell fate commitment)|go:"GO:0021983"(pituitary gland development)|go:"GO:0021984"(adenohypophysis development)|go:"GO:0022409"(positive regulation of cell-cell adhesion)|go:"GO:0030154"(cell differentiation)|go:"GO:0030900"(forebrain development)|go:"GO:0035019"(somatic stem cell population maintenance)|go:"GO:0035198"(miRNA binding)|go:"GO:0042246"(tissue regeneration)|go:"GO:0043281"(regulation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0043410"(positive regulation of MAPK cascade)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045165"(cell fate commitment)|go:"GO:0045597"(positive regulation of cell differentiation)|go:"GO:0045665"(negative regulation of neuron differentiation)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048839"(inner ear development)|go:"GO:0050680"(negative regulation of epithelial cell proliferation)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0070848"(response to growth factor)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:0097150"(neuronal stem cell population maintenance)|interpro:IPR009071(High mobility group box, HMG)|interpro:IPR022097|interpro:IPR032643|interpro:IPR036910|mint:P48431|rcsb pdb:1O4X|rcsb pdb:2LE4|rcsb pdb:6T7B|rcsb pdb:6T90|rcsb pdb:6WX7|rcsb pdb:6WX8|rcsb pdb:6WX9|rcsb pdb:6YOV|reactome:R-HSA-2892245|reactome:R-HSA-2892247|reactome:R-HSA-3769402|reactome:R-HSA-452723|reactome:R-HSA-6785807|reactome:R-HSA-8986944 ensembl:ENSG00000005302(gene)|ensembl:ENST00000312196(transcript)|go:"GO:0000123"(histone acetyltransferase complex)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006342"|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0016573"(histone acetylation)|go:"GO:0016575"(histone deacetylation)|go:"GO:0035064"(methylated histone binding)|go:"GO:0035267"(NuA4 histone acetyltransferase complex)|go:"GO:0043967"(histone H4 acetylation)|go:"GO:0043968"(histone H2A acetylation)|go:"GO:0043984"(histone H4-K16 acetylation)|go:"GO:0046972"("histone acetyltransferase activity (H4-K16 specific)")|go:"GO:0072487"(MSL complex)|interpro:IPR000953(Chromo domain)|interpro:IPR008676(MRG)|interpro:IPR016197(Chromo domain-like)|interpro:IPR025995|interpro:IPR026541|interpro:IPR037921|interpro:IPR038217|mint:Q8N5Y2|rcsb pdb:2Y0N|rcsb pdb:3OA6|rcsb pdb:3OB9|reactome:R-HSA-3214847|refseq:NP_001180199.1|refseq:NP_523352.1|refseq:NP_523353.2|refseq:NP_006791.2|refseq:NP_001269103.1|refseq:XP_005274497.1|dip:DIP-56857N go:"GO:0005634"(nucleus) - - figure legend:ST2 F2A|comment:proteins identified only in our induced samples in three MudPIT analyses with the more stringent BY-adjusted significance p<0.05|dataset:Brain Disease - Neurological Diseases & Disorders|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-daoy)|taxid:9606(Homo sapiens DAOY cerebellar medulloblastoma cell line) - 2020/12/29 2020/12/29 rogid:cn8gYfKDpQc8J2ygnqny32sIyyU9606 rogid:uZsUcEHPwWI+o+d7aGwhfnxVltA9606 rigid:6EMs5+B89Q89RCR/2S2BG6PhH9E false tandem tag:n-n - - - psi-mi:"MI:0658"(multidimensional protein identification technology) psi-mi:"MI:0658"(multidimensional protein identification technology) uniprotkb:P48431 uniprotkb:Q9HCK8 intact:EBI-6124081|uniprotkb:Q14537|ensembl:ENSP00000323588 intact:EBI-1169146|uniprotkb:Q68DQ0|uniprotkb:Q8N3Z9|uniprotkb:Q8NCY4|uniprotkb:Q8TBR9|uniprotkb:Q96F26|uniprotkb:Q4G0D8|uniprotkb:Q6DKH9|uniprotkb:Q6P440|uniprotkb:Q6ZNL7|ensembl:ENSP00000451601|ensembl:ENSP00000495070|ensembl:ENSP00000495240 psi-mi:sox2_human(display_long)|uniprotkb:SOX2(gene name)|psi-mi:SOX2(display_short) psi-mi:chd8_human(display_long)|uniprotkb:ATP-dependent helicase CHD8(gene name synonym)|uniprotkb:Helicase with SNF2 domain 1(gene name synonym)|uniprotkb:CHD8(gene name)|psi-mi:CHD8(display_short)|uniprotkb:HELSNF1(gene name synonym)|uniprotkb:KIAA1564(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Cox et al. (2012) pubmed:23667531|imex:IM-28599 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-26574619|imex:IM-28599-5 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_003097.1|dip:DIP-59913N|ensembl:ENSG00000181449(gene)|ensembl:ENST00000325404(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001649"(osteoblast differentiation)|go:"GO:0001654"(eye development)|go:"GO:0001714"(endodermal cell fate specification)|go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006325"(chromatin organization)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0009611"(response to wounding)|go:"GO:0009653"(anatomical structure morphogenesis)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0021781"(glial cell fate commitment)|go:"GO:0021983"(pituitary gland development)|go:"GO:0021984"(adenohypophysis development)|go:"GO:0022409"(positive regulation of cell-cell adhesion)|go:"GO:0030154"(cell differentiation)|go:"GO:0030900"(forebrain development)|go:"GO:0035019"(somatic stem cell population maintenance)|go:"GO:0035198"(miRNA binding)|go:"GO:0042246"(tissue regeneration)|go:"GO:0043281"(regulation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0043410"(positive regulation of MAPK cascade)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045165"(cell fate commitment)|go:"GO:0045597"(positive regulation of cell differentiation)|go:"GO:0045665"(negative regulation of neuron differentiation)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048839"(inner ear development)|go:"GO:0050680"(negative regulation of epithelial cell proliferation)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0070848"(response to growth factor)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:0097150"(neuronal stem cell population maintenance)|interpro:IPR009071(High mobility group box, HMG)|interpro:IPR022097|interpro:IPR032643|interpro:IPR036910|mint:P48431|rcsb pdb:1O4X|rcsb pdb:2LE4|rcsb pdb:6T7B|rcsb pdb:6T90|rcsb pdb:6WX7|rcsb pdb:6WX8|rcsb pdb:6WX9|rcsb pdb:6YOV|reactome:R-HSA-2892245|reactome:R-HSA-2892247|reactome:R-HSA-3769402|reactome:R-HSA-452723|reactome:R-HSA-6785807|reactome:R-HSA-8986944 ensembl:ENST00000430710|ensembl:ENSP00000406288|ensembl:ENSP00000451601|ensembl:ENSP00000495070|ensembl:ENST00000645929|ensembl:ENSP00000494402|ensembl:ENSP00000495240|refseq:NP_001164100.1|refseq:NP_065971.2|go:"GO:0035064"(methylated histone binding)|go:"GO:0035176"(social behavior)|go:"GO:0042393"(histone binding)|go:"GO:0043044"|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0045945"(positive regulation of transcription by RNA polymerase III)|go:"GO:0048565"(digestive tract development)|go:"GO:0060134"(prepulse inhibition)|go:"GO:0070016"(armadillo repeat domain binding)|go:"GO:0070615"|ensembl:ENSG00000100888(gene)|ensembl:ENST00000557364(transcript)|ensembl:ENST00000643469(transcript)|ensembl:ENST00000646647(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0002039"(p53 binding)|go:"GO:0003677"(DNA binding)|go:"GO:0003678"(DNA helicase activity)|go:"GO:0003682"(chromatin binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0007420"(brain development)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0008094"(ATP-dependent activity, acting on DNA)|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0032991"(protein-containing complex)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|go:"GO:2000270"(negative regulation of fibroblast apoptotic process)|interpro:IPR000330(SNF2-related)|interpro:IPR000953(Chromo domain)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR006576(BRK)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR016197(Chromo domain-like)|interpro:IPR023780|interpro:IPR027417|interpro:IPR034724|interpro:IPR037259|interpro:IPR038718|mint:Q9HCK8|rcsb pdb:2CKA|rcsb pdb:2DL6|reactome:R-HSA-3769402|go:"GO:0071339"(MLL1 complex)|dip:DIP-38021N go:"GO:0005634"(nucleus) - - figure legend:ST2 F2A|comment:proteins identified only in our induced samples in three MudPIT analyses with the more stringent BY-adjusted significance p<0.05|dataset:Brain Disease - Neurological Diseases & Disorders|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-daoy)|taxid:9606(Homo sapiens DAOY cerebellar medulloblastoma cell line) - 2020/12/29 2020/12/29 rogid:cn8gYfKDpQc8J2ygnqny32sIyyU9606 rogid:QwADLvHNwK00OAboBtAkqaICd489606 rigid:6EMs5+B89Q89RCR/2S2BG6PhH9E false tandem tag:n-n - - - psi-mi:"MI:0658"(multidimensional protein identification technology) psi-mi:"MI:0658"(multidimensional protein identification technology) uniprotkb:P48431 uniprotkb:Q9Y4E8 intact:EBI-6124081|uniprotkb:Q14537|ensembl:ENSP00000323588 intact:EBI-1043104|uniprotkb:Q9HCA6|uniprotkb:Q9UNP0|uniprotkb:Q9Y5B5|ensembl:ENSP00000280377|uniprotkb:Q9H8G9|uniprotkb:Q08AL5 psi-mi:sox2_human(display_long)|uniprotkb:SOX2(gene name)|psi-mi:SOX2(display_short) psi-mi:ubp15_human(display_long)|uniprotkb:Unph4(gene name synonym)|uniprotkb:USP15(gene name)|psi-mi:USP15(display_short)|uniprotkb:KIAA0529(gene name synonym)|uniprotkb:Ubiquitin-specific-processing protease 15(gene name synonym)|uniprotkb:Deubiquitinating enzyme 15(gene name synonym)|uniprotkb:Unph-2(gene name synonym)|uniprotkb:Ubiquitin thioesterase 15(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Cox et al. (2012) pubmed:23667531|imex:IM-28599 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-26574619|imex:IM-28599-5 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_003097.1|dip:DIP-59913N|ensembl:ENSG00000181449(gene)|ensembl:ENST00000325404(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001649"(osteoblast differentiation)|go:"GO:0001654"(eye development)|go:"GO:0001714"(endodermal cell fate specification)|go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006325"(chromatin organization)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0009611"(response to wounding)|go:"GO:0009653"(anatomical structure morphogenesis)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0021781"(glial cell fate commitment)|go:"GO:0021983"(pituitary gland development)|go:"GO:0021984"(adenohypophysis development)|go:"GO:0022409"(positive regulation of cell-cell adhesion)|go:"GO:0030154"(cell differentiation)|go:"GO:0030900"(forebrain development)|go:"GO:0035019"(somatic stem cell population maintenance)|go:"GO:0035198"(miRNA binding)|go:"GO:0042246"(tissue regeneration)|go:"GO:0043281"(regulation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0043410"(positive regulation of MAPK cascade)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045165"(cell fate commitment)|go:"GO:0045597"(positive regulation of cell differentiation)|go:"GO:0045665"(negative regulation of neuron differentiation)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048839"(inner ear development)|go:"GO:0050680"(negative regulation of epithelial cell proliferation)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0070848"(response to growth factor)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:0097150"(neuronal stem cell population maintenance)|interpro:IPR009071(High mobility group box, HMG)|interpro:IPR022097|interpro:IPR032643|interpro:IPR036910|mint:P48431|rcsb pdb:1O4X|rcsb pdb:2LE4|rcsb pdb:6T7B|rcsb pdb:6T90|rcsb pdb:6WX7|rcsb pdb:6WX8|rcsb pdb:6WX9|rcsb pdb:6YOV|reactome:R-HSA-2892245|reactome:R-HSA-2892247|reactome:R-HSA-3769402|reactome:R-HSA-452723|reactome:R-HSA-6785807|reactome:R-HSA-8986944 ensembl:ENSG00000135655(gene)|ensembl:ENST00000280377(transcript)|go:"GO:0004197"(cysteine-type endopeptidase activity)|go:"GO:0004843"(thiol-dependent deubiquitinase)|go:"GO:0005160"(transforming growth factor beta receptor binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0007179"(transforming growth factor beta receptor signaling pathway)|go:"GO:0016579"(protein deubiquitination)|go:"GO:0030509"(BMP signaling pathway)|go:"GO:0035520"(monoubiquitinated protein deubiquitination)|go:"GO:0035616"(histone H2B conserved C-terminal lysine deubiquitination)|go:"GO:0042802"(identical protein binding)|go:"GO:0046332"(SMAD binding)|go:"GO:0060389"(pathway-restricted SMAD protein phosphorylation)|go:"GO:0061649"(ubiquitin modification-dependent histone binding)|go:"GO:1900246"(positive regulation of RIG-I signaling pathway)|go:"GO:1905035"(negative regulation of antifungal innate immune response)|go:"GO:1990167"(protein K27-linked deubiquitination)|go:"GO:1990380"(Lys48-specific deubiquitinase activity)|interpro:IPR001394(Peptidase C19, ubiquitin carboxyl-terminal hydrolase 2)|interpro:IPR006615(Ubiquitin carboxyl-terminal hydrolase, N-terminal region 1)|interpro:IPR013792(RNA 3'-terminal phosphate cyclase/enolpyruvate transferase, alpha/beta)|interpro:IPR018200|interpro:IPR028135|interpro:IPR028889|interpro:IPR029071|interpro:IPR029346|interpro:IPR035927|interpro:IPR038765|mint:Q9Y4E8|rcsb pdb:1W6V|rcsb pdb:3LMN|rcsb pdb:3PPA|rcsb pdb:3PV1|rcsb pdb:3T9L|rcsb pdb:4A3O|rcsb pdb:4A3P|rcsb pdb:5JJW|rcsb pdb:6CPM|rcsb pdb:6CRN|rcsb pdb:6DJ9|rcsb pdb:6GH9|rcsb pdb:6GHA|rcsb pdb:6ML1|reactome:R-HSA-2173788|reactome:R-HSA-5689603|reactome:R-HSA-5689880|refseq:NP_006304.1|refseq:NP_001239008.1|refseq:NP_001239007.1|dip:DIP-50239N go:"GO:0005634"(nucleus) - - figure legend:ST2 F2A|comment:proteins identified only in our induced samples in three MudPIT analyses with the more stringent BY-adjusted significance p<0.05|dataset:Brain Disease - Neurological Diseases & Disorders|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-daoy)|taxid:9606(Homo sapiens DAOY cerebellar medulloblastoma cell line) - 2020/12/29 2020/12/29 rogid:cn8gYfKDpQc8J2ygnqny32sIyyU9606 rogid:Hjx7D3Eq+fTpjE3D3fUujJN9gW89606 rigid:6EMs5+B89Q89RCR/2S2BG6PhH9E false tandem tag:n-n - - - psi-mi:"MI:0658"(multidimensional protein identification technology) psi-mi:"MI:0658"(multidimensional protein identification technology) uniprotkb:P48431 uniprotkb:Q8IVH2 intact:EBI-6124081|uniprotkb:Q14537|ensembl:ENSP00000323588 intact:EBI-1054619|ensembl:ENSP00000309823|uniprotkb:Q5W098|uniprotkb:Q7Z7F8|uniprotkb:Q8IW55|uniprotkb:Q96E19 psi-mi:sox2_human(display_long)|uniprotkb:SOX2(gene name)|psi-mi:SOX2(display_short) psi-mi:foxp4_human(display_long)|uniprotkb:FOXP4(gene name)|psi-mi:FOXP4(display_short)|uniprotkb:FKHLA(gene name synonym)|uniprotkb:Fork head-related protein-like A(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Cox et al. (2012) pubmed:23667531|imex:IM-28599 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-26574619|imex:IM-28599-5 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_003097.1|dip:DIP-59913N|ensembl:ENSG00000181449(gene)|ensembl:ENST00000325404(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001649"(osteoblast differentiation)|go:"GO:0001654"(eye development)|go:"GO:0001714"(endodermal cell fate specification)|go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006325"(chromatin organization)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0009611"(response to wounding)|go:"GO:0009653"(anatomical structure morphogenesis)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0021781"(glial cell fate commitment)|go:"GO:0021983"(pituitary gland development)|go:"GO:0021984"(adenohypophysis development)|go:"GO:0022409"(positive regulation of cell-cell adhesion)|go:"GO:0030154"(cell differentiation)|go:"GO:0030900"(forebrain development)|go:"GO:0035019"(somatic stem cell population maintenance)|go:"GO:0035198"(miRNA binding)|go:"GO:0042246"(tissue regeneration)|go:"GO:0043281"(regulation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0043410"(positive regulation of MAPK cascade)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045165"(cell fate commitment)|go:"GO:0045597"(positive regulation of cell differentiation)|go:"GO:0045665"(negative regulation of neuron differentiation)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048839"(inner ear development)|go:"GO:0050680"(negative regulation of epithelial cell proliferation)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0070848"(response to growth factor)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:0097150"(neuronal stem cell population maintenance)|interpro:IPR009071(High mobility group box, HMG)|interpro:IPR022097|interpro:IPR032643|interpro:IPR036910|mint:P48431|rcsb pdb:1O4X|rcsb pdb:2LE4|rcsb pdb:6T7B|rcsb pdb:6T90|rcsb pdb:6WX7|rcsb pdb:6WX8|rcsb pdb:6WX9|rcsb pdb:6YOV|reactome:R-HSA-2892245|reactome:R-HSA-2892247|reactome:R-HSA-3769402|reactome:R-HSA-452723|reactome:R-HSA-6785807|reactome:R-HSA-8986944 refseq:NP_001012426.1|refseq:NP_001012427.1|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|interpro:IPR001766(Fork head transcription factor)|interpro:IPR030456|interpro:IPR032354|interpro:IPR036388|interpro:IPR036390|mint:Q8IVH2|ensembl:ENSG00000137166(gene)|ensembl:ENST00000307972(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0005634"(nucleus)|refseq:NP_612466.1|ensembl:ENSP00000362154|ensembl:ENSP00000309823|ensembl:ENST00000373057|ensembl:ENSP00000362148|ensembl:ENST00000373063|dip:DIP-59301N go:"GO:0005634"(nucleus) - - figure legend:ST2 F2A|comment:proteins identified only in our induced samples in three MudPIT analyses with the more stringent BY-adjusted significance p<0.05|dataset:Brain Disease - Neurological Diseases & Disorders|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-daoy)|taxid:9606(Homo sapiens DAOY cerebellar medulloblastoma cell line) - 2020/12/29 2020/12/29 rogid:cn8gYfKDpQc8J2ygnqny32sIyyU9606 rogid:8DDWFXo3USEol96m7tKQPHrEc5I9606 rigid:6EMs5+B89Q89RCR/2S2BG6PhH9E false tandem tag:n-n - - - psi-mi:"MI:0658"(multidimensional protein identification technology) psi-mi:"MI:0658"(multidimensional protein identification technology) uniprotkb:P48431 uniprotkb:P31323 intact:EBI-6124081|uniprotkb:Q14537|ensembl:ENSP00000323588 intact:EBI-2930670|ensembl:ENSP00000265717|ensembl:ENSP00000491687|uniprotkb:A4D0R9 psi-mi:sox2_human(display_long)|uniprotkb:SOX2(gene name)|psi-mi:SOX2(display_short) psi-mi:kap3_human(display_long)|uniprotkb:PRKAR2B(gene name)|psi-mi:PRKAR2B(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Cox et al. (2012) pubmed:23667531|imex:IM-28599 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-26574619|imex:IM-28599-5 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_003097.1|dip:DIP-59913N|ensembl:ENSG00000181449(gene)|ensembl:ENST00000325404(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001649"(osteoblast differentiation)|go:"GO:0001654"(eye development)|go:"GO:0001714"(endodermal cell fate specification)|go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006325"(chromatin organization)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0009611"(response to wounding)|go:"GO:0009653"(anatomical structure morphogenesis)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0021781"(glial cell fate commitment)|go:"GO:0021983"(pituitary gland development)|go:"GO:0021984"(adenohypophysis development)|go:"GO:0022409"(positive regulation of cell-cell adhesion)|go:"GO:0030154"(cell differentiation)|go:"GO:0030900"(forebrain development)|go:"GO:0035019"(somatic stem cell population maintenance)|go:"GO:0035198"(miRNA binding)|go:"GO:0042246"(tissue regeneration)|go:"GO:0043281"(regulation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0043410"(positive regulation of MAPK cascade)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045165"(cell fate commitment)|go:"GO:0045597"(positive regulation of cell differentiation)|go:"GO:0045665"(negative regulation of neuron differentiation)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048839"(inner ear development)|go:"GO:0050680"(negative regulation of epithelial cell proliferation)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0070848"(response to growth factor)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:0097150"(neuronal stem cell population maintenance)|interpro:IPR009071(High mobility group box, HMG)|interpro:IPR022097|interpro:IPR032643|interpro:IPR036910|mint:P48431|rcsb pdb:1O4X|rcsb pdb:2LE4|rcsb pdb:6T7B|rcsb pdb:6T90|rcsb pdb:6WX7|rcsb pdb:6WX8|rcsb pdb:6WX9|rcsb pdb:6YOV|reactome:R-HSA-2892245|reactome:R-HSA-2892247|reactome:R-HSA-3769402|reactome:R-HSA-452723|reactome:R-HSA-6785807|reactome:R-HSA-8986944 ensembl:ENSG00000005249(gene)|ensembl:ENSG00000284096(gene)|ensembl:ENST00000265717(transcript)|ensembl:ENST00000639737(transcript)|go:"GO:0004862"(cAMP-dependent protein kinase inhibitor activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006631"(fatty acid metabolic process)|go:"GO:0005952"(cAMP-dependent protein kinase complex)|go:"GO:0007612"(learning)|go:"GO:0008603"(cAMP-dependent protein kinase regulator activity)|go:"GO:0010738"(regulation of protein kinase A signaling)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030552"(cAMP binding)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0034236"(protein kinase A catalytic subunit binding)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043197"(dendritic spine)|go:"GO:0043198"(dendritic shaft)|go:"GO:0043949"(regulation of cAMP-mediated signaling)|go:"GO:0045121"(membrane raft)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0050804"(modulation of chemical synaptic transmission)|go:"GO:0070062"(extracellular exosome)|go:"GO:0097332"(response to antipsychotic drug)|go:"GO:0097338"(response to clozapine)|go:"GO:0097546"(ciliary base)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:2000480"(negative regulation of cAMP-dependent protein kinase activity)|interpro:IPR000595(Cyclic nucleotide-binding)|interpro:IPR003117(cAMP-dependent protein kinase, regulatory subunit, type I/II alpha/beta)|interpro:IPR012198(cAMP-dependent protein kinase regulatory subunit)|interpro:IPR014710(RmlC-like jelly roll fold)|interpro:IPR018488|interpro:IPR018490|mint:P31323|reactome:R-HSA-163615|reactome:R-HSA-164378|reactome:R-HSA-180024|reactome:R-HSA-2565942|reactome:R-HSA-380259|reactome:R-HSA-380270|reactome:R-HSA-380284|reactome:R-HSA-380320|reactome:R-HSA-381676|reactome:R-HSA-432040|reactome:R-HSA-442720|reactome:R-HSA-5610787|reactome:R-HSA-5620912|reactome:R-HSA-8854518|reactome:R-HSA-9660821|reactome:R-HSA-9664323|reactome:R-HSA-983231|refseq:NP_002727.2|dip:DIP-554N go:"GO:0005634"(nucleus) - - figure legend:ST2 F2A|comment:proteins identified only in our induced samples in three MudPIT analyses with the more stringent BY-adjusted significance p<0.05|dataset:Brain Disease - Neurological Diseases & Disorders|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-daoy)|taxid:9606(Homo sapiens DAOY cerebellar medulloblastoma cell line) - 2020/12/29 2020/12/29 rogid:cn8gYfKDpQc8J2ygnqny32sIyyU9606 rogid:P643dCCYtpt/EkR7tmZrbo97FLE9606 rigid:6EMs5+B89Q89RCR/2S2BG6PhH9E false tandem tag:n-n - - - psi-mi:"MI:0658"(multidimensional protein identification technology) psi-mi:"MI:0658"(multidimensional protein identification technology) uniprotkb:P48431 uniprotkb:P31483 intact:EBI-6124081|uniprotkb:Q14537|ensembl:ENSP00000323588 intact:EBI-1387216|uniprotkb:Q53SS9|uniprotkb:Q96B58|ensembl:ENSP00000401371 psi-mi:sox2_human(display_long)|uniprotkb:SOX2(gene name)|psi-mi:SOX2(display_short) psi-mi:tia1_human(display_long)|uniprotkb:TIA1(gene name)|psi-mi:TIA1(display_short)|uniprotkb:p40-TIA-1(gene name synonym)|uniprotkb:RNA-binding protein TIA-1(gene name synonym)|uniprotkb:T-cell-restricted intracellular antigen-1(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Cox et al. (2012) pubmed:23667531|imex:IM-28599 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-26574619|imex:IM-28599-5 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_003097.1|dip:DIP-59913N|ensembl:ENSG00000181449(gene)|ensembl:ENST00000325404(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001649"(osteoblast differentiation)|go:"GO:0001654"(eye development)|go:"GO:0001714"(endodermal cell fate specification)|go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006325"(chromatin organization)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0009611"(response to wounding)|go:"GO:0009653"(anatomical structure morphogenesis)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0021781"(glial cell fate commitment)|go:"GO:0021983"(pituitary gland development)|go:"GO:0021984"(adenohypophysis development)|go:"GO:0022409"(positive regulation of cell-cell adhesion)|go:"GO:0030154"(cell differentiation)|go:"GO:0030900"(forebrain development)|go:"GO:0035019"(somatic stem cell population maintenance)|go:"GO:0035198"(miRNA binding)|go:"GO:0042246"(tissue regeneration)|go:"GO:0043281"(regulation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0043410"(positive regulation of MAPK cascade)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045165"(cell fate commitment)|go:"GO:0045597"(positive regulation of cell differentiation)|go:"GO:0045665"(negative regulation of neuron differentiation)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048839"(inner ear development)|go:"GO:0050680"(negative regulation of epithelial cell proliferation)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0070848"(response to growth factor)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:0097150"(neuronal stem cell population maintenance)|interpro:IPR009071(High mobility group box, HMG)|interpro:IPR022097|interpro:IPR032643|interpro:IPR036910|mint:P48431|rcsb pdb:1O4X|rcsb pdb:2LE4|rcsb pdb:6T7B|rcsb pdb:6T90|rcsb pdb:6WX7|rcsb pdb:6WX8|rcsb pdb:6WX9|rcsb pdb:6YOV|reactome:R-HSA-2892245|reactome:R-HSA-2892247|reactome:R-HSA-3769402|reactome:R-HSA-452723|reactome:R-HSA-6785807|reactome:R-HSA-8986944 refseq:NP_071320.2|refseq:NP_071505.2|ensembl:ENSG00000116001(gene)|ensembl:ENST00000433529(transcript)|go:"GO:0001818"(negative regulation of cytokine production)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006915"(apoptotic process)|go:"GO:0008143"("poly(A) binding")|go:"GO:0010494"(cytoplasmic stress granule)|go:"GO:0017148"(negative regulation of translation)|go:"GO:0035925"(mRNA 3'-UTR AU-rich region binding)|go:"GO:0048024"(regulation of mRNA splicing, via spliceosome)|go:"GO:0097165"(nuclear stress granule)|go:"GO:1903608"(protein localization to cytoplasmic stress granule)|go:"GO:1904037"(positive regulation of epithelial cell apoptotic process)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR003954(RNA recognition, region 1)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR034830|interpro:IPR034832|interpro:IPR035979|rcsb pdb:2MJN|rcsb pdb:3BS9|rcsb pdb:5ITH|rcsb pdb:5O2V|rcsb pdb:5O3J|rcsb pdb:6ELD|reactome:R-HSA-6803529|mint:P31483 go:"GO:0005634"(nucleus) - - figure legend:ST2 F2A|comment:proteins identified only in our induced samples in three MudPIT analyses with the more stringent BY-adjusted significance p<0.05|dataset:Brain Disease - Neurological Diseases & Disorders|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-daoy)|taxid:9606(Homo sapiens DAOY cerebellar medulloblastoma cell line) - 2020/12/29 2020/12/29 rogid:cn8gYfKDpQc8J2ygnqny32sIyyU9606 rogid:d2ecwJo5sjSY6a/By3GM3B5A6PE9606 rigid:6EMs5+B89Q89RCR/2S2BG6PhH9E false tandem tag:n-n - - - psi-mi:"MI:0658"(multidimensional protein identification technology) psi-mi:"MI:0658"(multidimensional protein identification technology) uniprotkb:P48431 uniprotkb:O95071 intact:EBI-6124081|uniprotkb:Q14537|ensembl:ENSP00000323588 intact:EBI-358329|uniprotkb:O94970|uniprotkb:Q9NPL3|ensembl:ENSP00000429084|uniprotkb:B2RP24|intact:EBI-10967451|uniprotkb:J3KMW7 psi-mi:sox2_human(display_long)|uniprotkb:SOX2(gene name)|psi-mi:SOX2(display_short) psi-mi:ubr5_human(display_long)|uniprotkb:UBR5(gene name)|psi-mi:UBR5(display_short)|uniprotkb:HYD(gene name synonym)|uniprotkb:KIAA0896(gene name synonym)|uniprotkb:EDD(gene name synonym)|uniprotkb:EDD1(gene name synonym)|uniprotkb:E3 ubiquitin-protein ligase, HECT domain-containing 1(gene name synonym)|uniprotkb:Hyperplastic discs protein homolog(gene name synonym)|uniprotkb:Progestin-induced protein(gene name synonym)|uniprotkb:HECT-type E3 ubiquitin transferase UBR5(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Cox et al. (2012) pubmed:23667531|imex:IM-28599 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-26574619|imex:IM-28599-5 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_003097.1|dip:DIP-59913N|ensembl:ENSG00000181449(gene)|ensembl:ENST00000325404(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001649"(osteoblast differentiation)|go:"GO:0001654"(eye development)|go:"GO:0001714"(endodermal cell fate specification)|go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006325"(chromatin organization)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0009611"(response to wounding)|go:"GO:0009653"(anatomical structure morphogenesis)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0021781"(glial cell fate commitment)|go:"GO:0021983"(pituitary gland development)|go:"GO:0021984"(adenohypophysis development)|go:"GO:0022409"(positive regulation of cell-cell adhesion)|go:"GO:0030154"(cell differentiation)|go:"GO:0030900"(forebrain development)|go:"GO:0035019"(somatic stem cell population maintenance)|go:"GO:0035198"(miRNA binding)|go:"GO:0042246"(tissue regeneration)|go:"GO:0043281"(regulation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0043410"(positive regulation of MAPK cascade)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045165"(cell fate commitment)|go:"GO:0045597"(positive regulation of cell differentiation)|go:"GO:0045665"(negative regulation of neuron differentiation)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048839"(inner ear development)|go:"GO:0050680"(negative regulation of epithelial cell proliferation)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0070848"(response to growth factor)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:0097150"(neuronal stem cell population maintenance)|interpro:IPR009071(High mobility group box, HMG)|interpro:IPR022097|interpro:IPR032643|interpro:IPR036910|mint:P48431|rcsb pdb:1O4X|rcsb pdb:2LE4|rcsb pdb:6T7B|rcsb pdb:6T90|rcsb pdb:6WX7|rcsb pdb:6WX8|rcsb pdb:6WX9|rcsb pdb:6YOV|reactome:R-HSA-2892245|reactome:R-HSA-2892247|reactome:R-HSA-3769402|reactome:R-HSA-452723|reactome:R-HSA-6785807|reactome:R-HSA-8986944 refseq:NP_001269802.1|ensembl:ENST00000520539(transcript)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006281"(DNA repair)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0008270"(zinc ion binding)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0016020"(membrane)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034450"(ubiquitin-ubiquitin ligase activity)|go:"GO:0042307"(positive regulation of protein import into nucleus)|go:"GO:0043130"(ubiquitin binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0050847"(progesterone receptor signaling pathway)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0070936"(protein K48-linked ubiquitination)|go:"GO:0090263"(positive regulation of canonical Wnt signaling pathway)|go:"GO:1901315"(negative regulation of histone H2A K63-linked ubiquitination)|ensembl:ENSG00000104517(gene)|go:"GO:2000779"(regulation of double-strand break repair)|go:"GO:2000780"(negative regulation of double-strand break repair)|interpro:IPR000569(HECT)|interpro:IPR002004(Polyadenylate-binding protein/Hyperplastic disc protein)|interpro:IPR003126(Zinc finger, N-recognin)|interpro:IPR009091(Regulator of chromosome condensation/beta-lactamase-inhibitor protein II)|interpro:IPR024725|interpro:IPR035983|interpro:IPR036053|mint:O95071|rcsb pdb:1I2T|rcsb pdb:2QHO|refseq:NP_056986.2|rcsb pdb:3PT3|dip:DIP-32930N go:"GO:0005634"(nucleus) - - figure legend:ST2 F2A|comment:proteins identified only in our induced samples in three MudPIT analyses with the more stringent BY-adjusted significance p<0.05|dataset:Brain Disease - Neurological Diseases & Disorders|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-daoy)|taxid:9606(Homo sapiens DAOY cerebellar medulloblastoma cell line) - 2020/12/29 2020/12/29 rogid:cn8gYfKDpQc8J2ygnqny32sIyyU9606 rogid:5yiXAYJbV4iA8d3btwaVfL7vaik9606 rigid:6EMs5+B89Q89RCR/2S2BG6PhH9E false tandem tag:n-n - - - psi-mi:"MI:0658"(multidimensional protein identification technology) psi-mi:"MI:0658"(multidimensional protein identification technology) uniprotkb:P48431 uniprotkb:Q9BXB4 intact:EBI-6124081|uniprotkb:Q14537|ensembl:ENSP00000323588 intact:EBI-2514786|intact:EBI-28979243|ensembl:ENSP00000296220|uniprotkb:A8K9I7 psi-mi:sox2_human(display_long)|uniprotkb:SOX2(gene name)|psi-mi:SOX2(display_short) psi-mi:osb11_human(display_long)|uniprotkb:OSBPL11(gene name)|psi-mi:OSBPL11(display_short)|uniprotkb:ORP11(gene name synonym)|uniprotkb:OSBP12(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Cox et al. (2012) pubmed:23667531|imex:IM-28599 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-26574619|imex:IM-28599-5 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_003097.1|dip:DIP-59913N|ensembl:ENSG00000181449(gene)|ensembl:ENST00000325404(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001649"(osteoblast differentiation)|go:"GO:0001654"(eye development)|go:"GO:0001714"(endodermal cell fate specification)|go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006325"(chromatin organization)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0009611"(response to wounding)|go:"GO:0009653"(anatomical structure morphogenesis)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0021781"(glial cell fate commitment)|go:"GO:0021983"(pituitary gland development)|go:"GO:0021984"(adenohypophysis development)|go:"GO:0022409"(positive regulation of cell-cell adhesion)|go:"GO:0030154"(cell differentiation)|go:"GO:0030900"(forebrain development)|go:"GO:0035019"(somatic stem cell population maintenance)|go:"GO:0035198"(miRNA binding)|go:"GO:0042246"(tissue regeneration)|go:"GO:0043281"(regulation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0043410"(positive regulation of MAPK cascade)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045165"(cell fate commitment)|go:"GO:0045597"(positive regulation of cell differentiation)|go:"GO:0045665"(negative regulation of neuron differentiation)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048839"(inner ear development)|go:"GO:0050680"(negative regulation of epithelial cell proliferation)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0070848"(response to growth factor)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:0097150"(neuronal stem cell population maintenance)|interpro:IPR009071(High mobility group box, HMG)|interpro:IPR022097|interpro:IPR032643|interpro:IPR036910|mint:P48431|rcsb pdb:1O4X|rcsb pdb:2LE4|rcsb pdb:6T7B|rcsb pdb:6T90|rcsb pdb:6WX7|rcsb pdb:6WX8|rcsb pdb:6WX9|rcsb pdb:6YOV|reactome:R-HSA-2892245|reactome:R-HSA-2892247|reactome:R-HSA-3769402|reactome:R-HSA-452723|reactome:R-HSA-6785807|reactome:R-HSA-8986944 ensembl:ENSG00000144909(gene)|ensembl:ENST00000296220(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0010890"(positive regulation of sequestering of triglyceride)|go:"GO:0015248"(sterol transporter activity)|go:"GO:0016020"(membrane)|go:"GO:0031902"(late endosome membrane)|go:"GO:0032934"(sterol binding)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0045444"(fat cell differentiation)|interpro:IPR000648(Oxysterol-binding protein)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR018494|interpro:IPR037239|mint:Q9BXB4|rcsb pdb:2D9X|reactome:R-HSA-9013407|ensembl:ENSP00000296220|refseq:NP_073613.2 go:"GO:0005634"(nucleus) - - figure legend:ST2 F2A|comment:proteins identified only in our induced samples in three MudPIT analyses with the more stringent BY-adjusted significance p<0.05|dataset:Brain Disease - Neurological Diseases & Disorders|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-daoy)|taxid:9606(Homo sapiens DAOY cerebellar medulloblastoma cell line) - 2020/12/29 2020/12/29 rogid:cn8gYfKDpQc8J2ygnqny32sIyyU9606 rogid:KkLAr8dp83zeiK8iQg61QPEm2fs9606 rigid:6EMs5+B89Q89RCR/2S2BG6PhH9E false tandem tag:n-n - - - psi-mi:"MI:0658"(multidimensional protein identification technology) psi-mi:"MI:0658"(multidimensional protein identification technology) uniprotkb:P48431 uniprotkb:Q9Y4B6 intact:EBI-6124081|uniprotkb:Q14537|ensembl:ENSP00000323588 intact:EBI-1996353|uniprotkb:Q2YD74|uniprotkb:Q8TBD9|uniprotkb:Q9HCA1|uniprotkb:Q9UG37|intact:EBI-2559078|intact:EBI-28988191|ensembl:ENSP00000393183|ensembl:ENSP00000506880 psi-mi:sox2_human(display_long)|uniprotkb:SOX2(gene name)|psi-mi:SOX2(display_short) psi-mi:dcaf1_human(display_long)|uniprotkb:DCAF1(gene name)|psi-mi:DCAF1(display_short)|uniprotkb:HIV-1 Vpr-binding protein(gene name synonym)|uniprotkb:KIAA0800(gene name synonym)|uniprotkb:RIP(gene name synonym)|uniprotkb:Serine/threonine-protein kinase VPRBP(gene name synonym)|uniprotkb:VPRBP(gene name synonym)|uniprotkb:Vpr-interacting protein(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Cox et al. (2012) pubmed:23667531|imex:IM-28599 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-26574619|imex:IM-28599-5 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_003097.1|dip:DIP-59913N|ensembl:ENSG00000181449(gene)|ensembl:ENST00000325404(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001649"(osteoblast differentiation)|go:"GO:0001654"(eye development)|go:"GO:0001714"(endodermal cell fate specification)|go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006325"(chromatin organization)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0009611"(response to wounding)|go:"GO:0009653"(anatomical structure morphogenesis)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0021781"(glial cell fate commitment)|go:"GO:0021983"(pituitary gland development)|go:"GO:0021984"(adenohypophysis development)|go:"GO:0022409"(positive regulation of cell-cell adhesion)|go:"GO:0030154"(cell differentiation)|go:"GO:0030900"(forebrain development)|go:"GO:0035019"(somatic stem cell population maintenance)|go:"GO:0035198"(miRNA binding)|go:"GO:0042246"(tissue regeneration)|go:"GO:0043281"(regulation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0043410"(positive regulation of MAPK cascade)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045165"(cell fate commitment)|go:"GO:0045597"(positive regulation of cell differentiation)|go:"GO:0045665"(negative regulation of neuron differentiation)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048839"(inner ear development)|go:"GO:0050680"(negative regulation of epithelial cell proliferation)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0070848"(response to growth factor)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:0097150"(neuronal stem cell population maintenance)|interpro:IPR009071(High mobility group box, HMG)|interpro:IPR022097|interpro:IPR032643|interpro:IPR036910|mint:P48431|rcsb pdb:1O4X|rcsb pdb:2LE4|rcsb pdb:6T7B|rcsb pdb:6T90|rcsb pdb:6WX7|rcsb pdb:6WX8|rcsb pdb:6WX9|rcsb pdb:6YOV|reactome:R-HSA-2892245|reactome:R-HSA-2892247|reactome:R-HSA-3769402|reactome:R-HSA-452723|reactome:R-HSA-6785807|reactome:R-HSA-8986944 refseq:NP_001165375.1|refseq:NP_055518.1|refseq:XP_011532575.1|refseq:XP_011532576.1|refseq:XP_011532577.1|refseq:XP_011532578.1|refseq:XP_011532579.1|refseq:XP_016863035.1|refseq:XP_016863036.1|refseq:XP_016863037.1|refseq:XP_016863038.1|refseq:XP_016863039.1|ensembl:ENST00000335891|ensembl:ENSP00000338857|ensembl:ENSP00000393183|ensembl:ENST00000504652|ensembl:ENSP00000421724|ensembl:ENSP00000506880|ensembl:ENSG00000145041(gene)|ensembl:ENST00000423656(transcript)|ensembl:ENST00000684031(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0001650"(fibrillar center)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0030183"(B cell differentiation)|go:"GO:0030331"(estrogen receptor binding)|go:"GO:0033151"("V(D)J recombination")|go:"GO:0035212"(cell competition in a multicellular organism)|go:"GO:0080008"(Cul4-RING E3 ubiquitin ligase complex)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:1990244"("histone kinase activity (H2A-T120 specific)")|go:"GO:1990245"(histone H2A-T120 phosphorylation)|interpro:IPR006594(LisH dimerisation motif)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR033270|interpro:IPR036322|mint:Q9Y4B6|rcsb pdb:3WA0|rcsb pdb:4CC9|rcsb pdb:4P7I|rcsb pdb:4PXW|rcsb pdb:4Z8L|rcsb pdb:5AJA|rcsb pdb:5JK7|rcsb pdb:6N45|reactome:R-HSA-983168|refseq:XP_005276810.1|refseq:XP_005276812.1|dip:DIP-47048N go:"GO:0005634"(nucleus) - - figure legend:ST2 F2A|comment:proteins identified only in our induced samples in three MudPIT analyses with the more stringent BY-adjusted significance p<0.05|dataset:Brain Disease - Neurological Diseases & Disorders|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-daoy)|taxid:9606(Homo sapiens DAOY cerebellar medulloblastoma cell line) - 2020/12/29 2020/12/29 rogid:cn8gYfKDpQc8J2ygnqny32sIyyU9606 rogid:qs3qG0MM135EE/DjC1S/gCLRFhc9606 rigid:6EMs5+B89Q89RCR/2S2BG6PhH9E false tandem tag:n-n - - - psi-mi:"MI:0658"(multidimensional protein identification technology) psi-mi:"MI:0658"(multidimensional protein identification technology) uniprotkb:P48431 uniprotkb:Q9NYK5 intact:EBI-6124081|uniprotkb:Q14537|ensembl:ENSP00000323588 intact:EBI-2513042|ensembl:ENSP00000284967|uniprotkb:Q9BZV6|uniprotkb:Q32Q74|uniprotkb:Q9BSQ7|uniprotkb:Q5QTR3|uniprotkb:Q96Q65|uniprotkb:Q9NX44|uniprotkb:C9JYA5 psi-mi:sox2_human(display_long)|uniprotkb:SOX2(gene name)|psi-mi:SOX2(display_short) psi-mi:rm39_human(display_long)|uniprotkb:MRPL39(gene name)|psi-mi:MRPL39(display_short)|uniprotkb:C21orf92(gene name synonym)|uniprotkb:MRPL5(gene name synonym)|uniprotkb:RPML5(gene name synonym)|uniprotkb:39S ribosomal protein L5, mitochondrial(gene name synonym)|uniprotkb:MSTP003(orf name)|uniprotkb:PRED22(orf name)|uniprotkb:Mitochondrial large ribosomal subunit protein mL39(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Cox et al. (2012) pubmed:23667531|imex:IM-28599 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-26574619|imex:IM-28599-5 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_003097.1|dip:DIP-59913N|ensembl:ENSG00000181449(gene)|ensembl:ENST00000325404(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001649"(osteoblast differentiation)|go:"GO:0001654"(eye development)|go:"GO:0001714"(endodermal cell fate specification)|go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006325"(chromatin organization)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0009611"(response to wounding)|go:"GO:0009653"(anatomical structure morphogenesis)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0021781"(glial cell fate commitment)|go:"GO:0021983"(pituitary gland development)|go:"GO:0021984"(adenohypophysis development)|go:"GO:0022409"(positive regulation of cell-cell adhesion)|go:"GO:0030154"(cell differentiation)|go:"GO:0030900"(forebrain development)|go:"GO:0035019"(somatic stem cell population maintenance)|go:"GO:0035198"(miRNA binding)|go:"GO:0042246"(tissue regeneration)|go:"GO:0043281"(regulation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0043410"(positive regulation of MAPK cascade)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045165"(cell fate commitment)|go:"GO:0045597"(positive regulation of cell differentiation)|go:"GO:0045665"(negative regulation of neuron differentiation)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048839"(inner ear development)|go:"GO:0050680"(negative regulation of epithelial cell proliferation)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0070848"(response to growth factor)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:0097150"(neuronal stem cell population maintenance)|interpro:IPR009071(High mobility group box, HMG)|interpro:IPR022097|interpro:IPR032643|interpro:IPR036910|mint:P48431|rcsb pdb:1O4X|rcsb pdb:2LE4|rcsb pdb:6T7B|rcsb pdb:6T90|rcsb pdb:6WX7|rcsb pdb:6WX8|rcsb pdb:6WX9|rcsb pdb:6YOV|reactome:R-HSA-2892245|reactome:R-HSA-2892247|reactome:R-HSA-3769402|reactome:R-HSA-452723|reactome:R-HSA-6785807|reactome:R-HSA-8986944 ensembl:ENSG00000154719(gene)|ensembl:ENST00000352957(transcript)|go:"GO:0000166"(nucleotide binding)|go:"GO:0003723"(RNA binding)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005761"(mitochondrial ribosome)|go:"GO:0005762"(mitochondrial large ribosomal subunit)|interpro:IPR004095(TGS)|interpro:IPR012675(Beta-grasp fold, ferredoxin-type)|interpro:IPR012676(TGS-like)|interpro:IPR018163|mint:Q9NYK5|rcsb pdb:3J7Y|rcsb pdb:3J9M|rcsb pdb:5OOL|rcsb pdb:5OOM|rcsb pdb:6I9R|rcsb pdb:6NU2|rcsb pdb:6VLZ|rcsb pdb:6VMI|rcsb pdb:6ZM5|rcsb pdb:6ZM6|rcsb pdb:6ZS9|rcsb pdb:6ZSA|rcsb pdb:6ZSB|rcsb pdb:6ZSC|rcsb pdb:6ZSD|rcsb pdb:6ZSE|rcsb pdb:6ZSG|rcsb pdb:7A5F|rcsb pdb:7A5G|rcsb pdb:7A5H|rcsb pdb:7A5I|rcsb pdb:7A5J|rcsb pdb:7A5K|rcsb pdb:7L08|rcsb pdb:7L20|rcsb pdb:7O9K|rcsb pdb:7O9M|rcsb pdb:7ODR|rcsb pdb:7ODS|rcsb pdb:7ODT|rcsb pdb:7OF0|rcsb pdb:7OF2|rcsb pdb:7OF3|rcsb pdb:7OF4|rcsb pdb:7OF5|rcsb pdb:7OF6|rcsb pdb:7OF7|rcsb pdb:7OG4|reactome:R-HSA-5368286|reactome:R-HSA-5389840|reactome:R-HSA-5419276|rcsb pdb:6NU3|refseq:NP_059142.2|refseq:NP_542984.2|refseq:XP_006724089.1 go:"GO:0005634"(nucleus) - - figure legend:ST2 F2A|comment:proteins identified only in our induced samples in three MudPIT analyses with the more stringent BY-adjusted significance p<0.05|dataset:Brain Disease - Neurological Diseases & Disorders|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-daoy)|taxid:9606(Homo sapiens DAOY cerebellar medulloblastoma cell line) - 2020/12/29 2020/12/29 rogid:cn8gYfKDpQc8J2ygnqny32sIyyU9606 rogid:yolHEKnYRC1KwprZYyWZXZmjgr89606 rigid:6EMs5+B89Q89RCR/2S2BG6PhH9E false tandem tag:n-n - - - psi-mi:"MI:0658"(multidimensional protein identification technology) psi-mi:"MI:0658"(multidimensional protein identification technology) uniprotkb:P48431 uniprotkb:P06493 intact:EBI-6124081|uniprotkb:Q14537|ensembl:ENSP00000323588 intact:EBI-444308|ensembl:ENSP00000378699|uniprotkb:O60764|uniprotkb:C9J497|uniprotkb:A8K7C4 psi-mi:sox2_human(display_long)|uniprotkb:SOX2(gene name)|psi-mi:SOX2(display_short) psi-mi:cdk1_human(display_long)|uniprotkb:p34 protein kinase(gene name synonym)|uniprotkb:Cell division protein kinase 1(gene name synonym)|uniprotkb:CDK1(gene name)|psi-mi:CDK1(display_short)|uniprotkb:CDC2(gene name synonym)|uniprotkb:Cell division control protein 2 homolog(gene name synonym)|uniprotkb:CDC28A(gene name synonym)|uniprotkb:CDKN1(gene name synonym)|uniprotkb:P34CDC2(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Cox et al. (2012) pubmed:23667531|imex:IM-28599 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-26574619|imex:IM-28599-5 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_003097.1|dip:DIP-59913N|ensembl:ENSG00000181449(gene)|ensembl:ENST00000325404(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001649"(osteoblast differentiation)|go:"GO:0001654"(eye development)|go:"GO:0001714"(endodermal cell fate specification)|go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006325"(chromatin organization)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0009611"(response to wounding)|go:"GO:0009653"(anatomical structure morphogenesis)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0021781"(glial cell fate commitment)|go:"GO:0021983"(pituitary gland development)|go:"GO:0021984"(adenohypophysis development)|go:"GO:0022409"(positive regulation of cell-cell adhesion)|go:"GO:0030154"(cell differentiation)|go:"GO:0030900"(forebrain development)|go:"GO:0035019"(somatic stem cell population maintenance)|go:"GO:0035198"(miRNA binding)|go:"GO:0042246"(tissue regeneration)|go:"GO:0043281"(regulation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0043410"(positive regulation of MAPK cascade)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045165"(cell fate commitment)|go:"GO:0045597"(positive regulation of cell differentiation)|go:"GO:0045665"(negative regulation of neuron differentiation)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048839"(inner ear development)|go:"GO:0050680"(negative regulation of epithelial cell proliferation)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0070848"(response to growth factor)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:0097150"(neuronal stem cell population maintenance)|interpro:IPR009071(High mobility group box, HMG)|interpro:IPR022097|interpro:IPR032643|interpro:IPR036910|mint:P48431|rcsb pdb:1O4X|rcsb pdb:2LE4|rcsb pdb:6T7B|rcsb pdb:6T90|rcsb pdb:6WX7|rcsb pdb:6WX8|rcsb pdb:6WX9|rcsb pdb:6YOV|reactome:R-HSA-2892245|reactome:R-HSA-2892247|reactome:R-HSA-3769402|reactome:R-HSA-452723|reactome:R-HSA-6785807|reactome:R-HSA-8986944 go:"GO:0006281"(DNA repair)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0006915"(apoptotic process)|go:"GO:0007095"(mitotic G2 DNA damage checkpoint signaling)|go:"GO:0007098"(centrosome cycle)|go:"GO:0007344"(pronuclear fusion)|go:"GO:0007569"(cell aging)|go:"GO:0008353"(RNA polymerase II CTD heptapeptide repeat kinase activity)|go:"GO:0009636"(response to toxic substance)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0010971"(positive regulation of G2/M transition of mitotic cell cycle)|go:"GO:0014038"(regulation of Schwann cell differentiation)|go:"GO:0014070"(response to organic cyclic compound)|go:"GO:0014075"(response to amine)|go:"GO:0014823"(response to activity)|go:"GO:0016020"(membrane)|go:"GO:0016477"(cell migration)|go:"GO:0016579"(protein deubiquitination)|go:"GO:0018105"(peptidyl-serine phosphorylation)|go:"GO:0018107"(peptidyl-threonine phosphorylation)|go:"GO:0030261"(chromosome condensation)|go:"GO:0030332"(cyclin binding)|go:"GO:0030496"(midbody)|go:"GO:0030855"(epithelial cell differentiation)|go:"GO:0031100"(animal organ regeneration)|go:"GO:0034501"(protein localization to kinetochore)|go:"GO:0035173"(histone kinase activity)|go:"GO:0006260"(DNA replication)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0045471"(response to ethanol)|go:"GO:0045740"(positive regulation of DNA replication)|go:"GO:0045995"(regulation of embryonic development)|go:"GO:0046686"(response to cadmium ion)|go:"GO:0046688"(response to copper ion)|go:"GO:0048511"(rhythmic process)|go:"GO:0048678"(response to axon injury)|go:"GO:0051301"(cell division)|go:"GO:0055015"(ventricular cardiac muscle cell development)|go:"GO:0060045"(positive regulation of cardiac muscle cell proliferation)|go:"GO:0042307"(positive regulation of protein import into nucleus)|go:"GO:0065003"(protein-containing complex assembly)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070301"(cellular response to hydrogen peroxide)|go:"GO:0070371"(ERK1 and ERK2 cascade)|go:"GO:0042493"|go:"GO:0072686"(mitotic spindle)|go:"GO:0090166"(Golgi disassembly)|go:"GO:0097125"(cyclin B1-CDK1 complex)|go:"GO:0097472"(cyclin-dependent protein kinase activity)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:1900182"(positive regulation of protein localization to nucleus)|go:"GO:1905448"(positive regulation of mitochondrial ATP synthesis coupled electron transport)|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|mint:P06493|rcsb pdb:1LC9|rcsb pdb:4Y72|rcsb pdb:4YC3|rcsb pdb:4YC6|rcsb pdb:5HQ0|rcsb pdb:5LQF|rcsb pdb:6GU2|rcsb pdb:6GU3|rcsb pdb:6GU4|rcsb pdb:6GU6|go:"GO:0042752"(regulation of circadian rhythm)|rcsb pdb:6GU7|rcsb pdb:6TWN|reactome:R-HSA-110056|reactome:R-HSA-113507|reactome:R-HSA-1362300|reactome:R-HSA-162658|reactome:R-HSA-170145|reactome:R-HSA-174048|reactome:R-HSA-174184|reactome:R-HSA-176408|reactome:R-HSA-176412|reactome:R-HSA-176417|reactome:R-HSA-2299718|reactome:R-HSA-2465910|reactome:R-HSA-2500257|reactome:R-HSA-2514853|reactome:R-HSA-2565942|reactome:R-HSA-2980767|reactome:R-HSA-2995383|reactome:R-HSA-3301854|reactome:R-HSA-380259|reactome:R-HSA-380270|reactome:R-HSA-380284|reactome:R-HSA-380320|reactome:R-HSA-4419969|reactome:R-HSA-5620912|reactome:R-HSA-5687128|reactome:R-HSA-5689896|reactome:R-HSA-6804114|reactome:R-HSA-6804757|reactome:R-HSA-68875|reactome:R-HSA-69205|reactome:R-HSA-69273|reactome:R-HSA-69478|reactome:R-HSA-75035|reactome:R-HSA-8852276|reactome:R-HSA-8854518|reactome:R-HSA-8878166|ensembl:ENSG00000170312(gene)|ensembl:ENST00000395284(transcript)|go:"GO:0000086"(G2/M transition of mitotic cell cycle)|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0000307"(cyclin-dependent protein kinase holoenzyme complex)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0001618"(virus receptor activity)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0004693"(cyclin-dependent protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005876"(spindle microtubule)|refseq:NP_001777.1|refseq:NP_203698.1|refseq:XP_005270360.1|refseq:NP_001307847.1|dip:DIP-35N go:"GO:0005634"(nucleus) - - figure legend:ST2 F2A|comment:proteins identified only in our induced samples in three MudPIT analyses with the more stringent BY-adjusted significance p<0.05|dataset:Brain Disease - Neurological Diseases & Disorders|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-daoy)|taxid:9606(Homo sapiens DAOY cerebellar medulloblastoma cell line) - 2020/12/29 2020/12/29 rogid:cn8gYfKDpQc8J2ygnqny32sIyyU9606 rogid:8geyXVp0Rpm8sG8I76/XgWsZ4JA9606 rigid:6EMs5+B89Q89RCR/2S2BG6PhH9E false tandem tag:n-n - - - psi-mi:"MI:0658"(multidimensional protein identification technology) psi-mi:"MI:0658"(multidimensional protein identification technology) uniprotkb:P48431 uniprotkb:Q9BTC8 intact:EBI-6124081|uniprotkb:Q14537|ensembl:ENSP00000323588 intact:EBI-2461787|uniprotkb:Q9NSP2|uniprotkb:Q9ULF4|ensembl:ENSP00000385823 psi-mi:sox2_human(display_long)|uniprotkb:SOX2(gene name)|psi-mi:SOX2(display_short) psi-mi:mta3_human(display_long)|uniprotkb:MTA3(gene name)|psi-mi:MTA3(display_short)|uniprotkb:KIAA1266(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Cox et al. (2012) pubmed:23667531|imex:IM-28599 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-26574619|imex:IM-28599-5 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_003097.1|dip:DIP-59913N|ensembl:ENSG00000181449(gene)|ensembl:ENST00000325404(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001649"(osteoblast differentiation)|go:"GO:0001654"(eye development)|go:"GO:0001714"(endodermal cell fate specification)|go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006325"(chromatin organization)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0009611"(response to wounding)|go:"GO:0009653"(anatomical structure morphogenesis)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0021781"(glial cell fate commitment)|go:"GO:0021983"(pituitary gland development)|go:"GO:0021984"(adenohypophysis development)|go:"GO:0022409"(positive regulation of cell-cell adhesion)|go:"GO:0030154"(cell differentiation)|go:"GO:0030900"(forebrain development)|go:"GO:0035019"(somatic stem cell population maintenance)|go:"GO:0035198"(miRNA binding)|go:"GO:0042246"(tissue regeneration)|go:"GO:0043281"(regulation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0043410"(positive regulation of MAPK cascade)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045165"(cell fate commitment)|go:"GO:0045597"(positive regulation of cell differentiation)|go:"GO:0045665"(negative regulation of neuron differentiation)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048839"(inner ear development)|go:"GO:0050680"(negative regulation of epithelial cell proliferation)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0070848"(response to growth factor)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:0097150"(neuronal stem cell population maintenance)|interpro:IPR009071(High mobility group box, HMG)|interpro:IPR022097|interpro:IPR032643|interpro:IPR036910|mint:P48431|rcsb pdb:1O4X|rcsb pdb:2LE4|rcsb pdb:6T7B|rcsb pdb:6T90|rcsb pdb:6WX7|rcsb pdb:6WX8|rcsb pdb:6WX9|rcsb pdb:6YOV|reactome:R-HSA-2892245|reactome:R-HSA-2892247|reactome:R-HSA-3769402|reactome:R-HSA-452723|reactome:R-HSA-6785807|reactome:R-HSA-8986944 refseq:NP_001269684.1|refseq:NP_001269685.1|refseq:NP_065795.1|refseq:NP_001317371.1|dip:DIP-47460N|ensembl:ENST00000405094(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0003682"(chromatin binding)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0008270"(zinc ion binding)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0010971"(positive regulation of G2/M transition of mitotic cell cycle)|go:"GO:0016575"(histone deacetylation)|go:"GO:0016581"(NuRD complex)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|interpro:IPR000679(Zinc finger, GATA-type)|interpro:IPR000949(ELM2)|interpro:IPR001005(SANT, DNA-binding)|interpro:IPR001025(Bromo adjacent region)|interpro:IPR009057(Homeodomain-like)|interpro:IPR017884|interpro:IPR017930|interpro:IPR035170|interpro:IPR040138|interpro:IPR043151|mint:Q9BTC8|reactome:R-HSA-3214815|reactome:R-HSA-427389|reactome:R-HSA-73762|reactome:R-HSA-8943724|reactome:R-HSA-9679191|ensembl:ENSG00000057935(gene) go:"GO:0005634"(nucleus) - - figure legend:ST2 F2A|comment:proteins identified only in our induced samples in three MudPIT analyses with the more stringent BY-adjusted significance p<0.05|dataset:Brain Disease - Neurological Diseases & Disorders|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-daoy)|taxid:9606(Homo sapiens DAOY cerebellar medulloblastoma cell line) - 2020/12/29 2020/12/29 rogid:cn8gYfKDpQc8J2ygnqny32sIyyU9606 rogid:wxPsfH6FguY8n4PFwaj1iJNTWPc9606 rigid:6EMs5+B89Q89RCR/2S2BG6PhH9E false tandem tag:n-n - - - psi-mi:"MI:0658"(multidimensional protein identification technology) psi-mi:"MI:0658"(multidimensional protein identification technology) uniprotkb:P48431 uniprotkb:Q8IVW6 intact:EBI-6124081|uniprotkb:Q14537|ensembl:ENSP00000323588 intact:EBI-5458329|uniprotkb:O95443|uniprotkb:Q59HC9|uniprotkb:Q6P9C9|ensembl:ENSP00000477878 psi-mi:sox2_human(display_long)|uniprotkb:SOX2(gene name)|psi-mi:SOX2(display_short) psi-mi:ari3b_human(display_long)|uniprotkb:ARID3B(gene name)|psi-mi:ARID3B(display_short)|uniprotkb:BDP(gene name synonym)|uniprotkb:DRIL2(gene name synonym)|uniprotkb:Bright and dead ringer protein(gene name synonym)|uniprotkb:Bright-like protein(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Cox et al. (2012) pubmed:23667531|imex:IM-28599 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-26574619|imex:IM-28599-5 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_003097.1|dip:DIP-59913N|ensembl:ENSG00000181449(gene)|ensembl:ENST00000325404(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001649"(osteoblast differentiation)|go:"GO:0001654"(eye development)|go:"GO:0001714"(endodermal cell fate specification)|go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006325"(chromatin organization)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0009611"(response to wounding)|go:"GO:0009653"(anatomical structure morphogenesis)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0021781"(glial cell fate commitment)|go:"GO:0021983"(pituitary gland development)|go:"GO:0021984"(adenohypophysis development)|go:"GO:0022409"(positive regulation of cell-cell adhesion)|go:"GO:0030154"(cell differentiation)|go:"GO:0030900"(forebrain development)|go:"GO:0035019"(somatic stem cell population maintenance)|go:"GO:0035198"(miRNA binding)|go:"GO:0042246"(tissue regeneration)|go:"GO:0043281"(regulation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0043410"(positive regulation of MAPK cascade)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045165"(cell fate commitment)|go:"GO:0045597"(positive regulation of cell differentiation)|go:"GO:0045665"(negative regulation of neuron differentiation)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048839"(inner ear development)|go:"GO:0050680"(negative regulation of epithelial cell proliferation)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0070848"(response to growth factor)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:0097150"(neuronal stem cell population maintenance)|interpro:IPR009071(High mobility group box, HMG)|interpro:IPR022097|interpro:IPR032643|interpro:IPR036910|mint:P48431|rcsb pdb:1O4X|rcsb pdb:2LE4|rcsb pdb:6T7B|rcsb pdb:6T90|rcsb pdb:6WX7|rcsb pdb:6WX8|rcsb pdb:6WX9|rcsb pdb:6YOV|reactome:R-HSA-2892245|reactome:R-HSA-2892247|reactome:R-HSA-3769402|reactome:R-HSA-452723|reactome:R-HSA-6785807|reactome:R-HSA-8986944 refseq:NP_001294868.1|refseq:NP_006456.1|ensembl:ENSG00000179361(gene)|ensembl:ENST00000622429(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|interpro:IPR001606(AT-rich interaction region)|interpro:IPR023334|mint:Q8IVW6|interpro:IPR036431 go:"GO:0005634"(nucleus) - - figure legend:ST2 F2A|comment:proteins identified only in our induced samples in three MudPIT analyses with the more stringent BY-adjusted significance p<0.05|dataset:Brain Disease - Neurological Diseases & Disorders|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-daoy)|taxid:9606(Homo sapiens DAOY cerebellar medulloblastoma cell line) - 2020/12/29 2020/12/29 rogid:cn8gYfKDpQc8J2ygnqny32sIyyU9606 rogid:wlZYnH9qjM7VzFUtrNLlqJhRXx49606 rigid:6EMs5+B89Q89RCR/2S2BG6PhH9E false tandem tag:n-n - - - psi-mi:"MI:0658"(multidimensional protein identification technology) psi-mi:"MI:0658"(multidimensional protein identification technology) uniprotkb:P48431 uniprotkb:Q9UL15 intact:EBI-6124081|uniprotkb:Q14537|ensembl:ENSP00000323588 intact:EBI-356517|uniprotkb:O94950|uniprotkb:Q86W59|ensembl:ENSP00000299204|ensembl:ENSP00000391713 psi-mi:sox2_human(display_long)|uniprotkb:SOX2(gene name)|psi-mi:SOX2(display_short) psi-mi:bag5_human(display_long)|uniprotkb:BAG5(gene name)|psi-mi:BAG5(display_short)|uniprotkb:KIAA0873(gene name synonym)|uniprotkb:Bcl-2-associated athanogene 5(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Cox et al. (2012) pubmed:23667531|imex:IM-28599 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-26574619|imex:IM-28599-5 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_003097.1|dip:DIP-59913N|ensembl:ENSG00000181449(gene)|ensembl:ENST00000325404(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001649"(osteoblast differentiation)|go:"GO:0001654"(eye development)|go:"GO:0001714"(endodermal cell fate specification)|go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006325"(chromatin organization)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0009611"(response to wounding)|go:"GO:0009653"(anatomical structure morphogenesis)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0021781"(glial cell fate commitment)|go:"GO:0021983"(pituitary gland development)|go:"GO:0021984"(adenohypophysis development)|go:"GO:0022409"(positive regulation of cell-cell adhesion)|go:"GO:0030154"(cell differentiation)|go:"GO:0030900"(forebrain development)|go:"GO:0035019"(somatic stem cell population maintenance)|go:"GO:0035198"(miRNA binding)|go:"GO:0042246"(tissue regeneration)|go:"GO:0043281"(regulation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0043410"(positive regulation of MAPK cascade)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045165"(cell fate commitment)|go:"GO:0045597"(positive regulation of cell differentiation)|go:"GO:0045665"(negative regulation of neuron differentiation)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048839"(inner ear development)|go:"GO:0050680"(negative regulation of epithelial cell proliferation)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0070848"(response to growth factor)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:0097150"(neuronal stem cell population maintenance)|interpro:IPR009071(High mobility group box, HMG)|interpro:IPR022097|interpro:IPR032643|interpro:IPR036910|mint:P48431|rcsb pdb:1O4X|rcsb pdb:2LE4|rcsb pdb:6T7B|rcsb pdb:6T90|rcsb pdb:6WX7|rcsb pdb:6WX8|rcsb pdb:6WX9|rcsb pdb:6YOV|reactome:R-HSA-2892245|reactome:R-HSA-2892247|reactome:R-HSA-3769402|reactome:R-HSA-452723|reactome:R-HSA-6785807|reactome:R-HSA-8986944 refseq:NP_001015048.1|refseq:NP_001015049.1|refseq:NP_004864.1|go:"GO:0051444"(negative regulation of ubiquitin-protein transferase activity)|go:"GO:0061084"(negative regulation of protein refolding)|go:"GO:0070997"(neuron death)|go:"GO:0090083"(regulation of inclusion body assembly)|go:"GO:1902176"(negative regulation of oxidative stress-induced intrinsic apoptotic signaling pathway)|interpro:IPR003103(Apoptosis regulator Bcl-2 protein, BAG)|interpro:IPR036533|interpro:IPR039773|mint:Q9UL15|rcsb pdb:2D9D|rcsb pdb:3A8Y|reactome:R-HSA-3371453|go:"GO:0051438"(regulation of ubiquitin-protein transferase activity)|ensembl:ENSG00000166170(gene)|ensembl:ENST00000299204(transcript)|ensembl:ENST00000445922(transcript)|go:"GO:0000774"(adenyl-nucleotide exchange factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0006457"(protein folding)|go:"GO:0007030"(Golgi organization)|go:"GO:0010977"(negative regulation of neuron projection development)|go:"GO:0016020"(membrane)|go:"GO:0016234"(inclusion body)|go:"GO:0019901"(protein kinase binding)|go:"GO:0031072"(heat shock protein binding)|go:"GO:0031397"(negative regulation of protein ubiquitination)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032435"(negative regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0050821"(protein stabilization)|go:"GO:0051087"(chaperone binding)|dip:DIP-53428N go:"GO:0005634"(nucleus) - - figure legend:ST2 F2A|comment:proteins identified only in our induced samples in three MudPIT analyses with the more stringent BY-adjusted significance p<0.05|dataset:Brain Disease - Neurological Diseases & Disorders|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-daoy)|taxid:9606(Homo sapiens DAOY cerebellar medulloblastoma cell line) - 2020/12/29 2020/12/29 rogid:cn8gYfKDpQc8J2ygnqny32sIyyU9606 rogid:I5E45kk4QcYF/BEa5qh7IBeBzF09606 rigid:6EMs5+B89Q89RCR/2S2BG6PhH9E false tandem tag:n-n - - - psi-mi:"MI:0658"(multidimensional protein identification technology) psi-mi:"MI:0658"(multidimensional protein identification technology) uniprotkb:P48431 uniprotkb:P49406 intact:EBI-6124081|uniprotkb:Q14537|ensembl:ENSP00000323588 intact:EBI-1188518|uniprotkb:Q96Q52|uniprotkb:Q53TX9|ensembl:ENSP00000377486|ensembl:ENSP00000387284 psi-mi:sox2_human(display_long)|uniprotkb:SOX2(gene name)|psi-mi:SOX2(display_short) psi-mi:rm19_human(display_long)|uniprotkb:MRPL15(gene name synonym)|uniprotkb:39S ribosomal protein L15, mitochondrial(gene name synonym)|uniprotkb:MRPL19(gene name)|psi-mi:MRPL19(display_short)|uniprotkb:KIAA0104(gene name synonym)|uniprotkb:Mitochondrial large ribosomal subunit protein bL19m(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Cox et al. (2012) pubmed:23667531|imex:IM-28599 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-26574619|imex:IM-28599-5 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_003097.1|dip:DIP-59913N|ensembl:ENSG00000181449(gene)|ensembl:ENST00000325404(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001649"(osteoblast differentiation)|go:"GO:0001654"(eye development)|go:"GO:0001714"(endodermal cell fate specification)|go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006325"(chromatin organization)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0009611"(response to wounding)|go:"GO:0009653"(anatomical structure morphogenesis)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0021781"(glial cell fate commitment)|go:"GO:0021983"(pituitary gland development)|go:"GO:0021984"(adenohypophysis development)|go:"GO:0022409"(positive regulation of cell-cell adhesion)|go:"GO:0030154"(cell differentiation)|go:"GO:0030900"(forebrain development)|go:"GO:0035019"(somatic stem cell population maintenance)|go:"GO:0035198"(miRNA binding)|go:"GO:0042246"(tissue regeneration)|go:"GO:0043281"(regulation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0043410"(positive regulation of MAPK cascade)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045165"(cell fate commitment)|go:"GO:0045597"(positive regulation of cell differentiation)|go:"GO:0045665"(negative regulation of neuron differentiation)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048839"(inner ear development)|go:"GO:0050680"(negative regulation of epithelial cell proliferation)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0070848"(response to growth factor)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:0097150"(neuronal stem cell population maintenance)|interpro:IPR009071(High mobility group box, HMG)|interpro:IPR022097|interpro:IPR032643|interpro:IPR036910|mint:P48431|rcsb pdb:1O4X|rcsb pdb:2LE4|rcsb pdb:6T7B|rcsb pdb:6T90|rcsb pdb:6WX7|rcsb pdb:6WX8|rcsb pdb:6WX9|rcsb pdb:6YOV|reactome:R-HSA-2892245|reactome:R-HSA-2892247|reactome:R-HSA-3769402|reactome:R-HSA-452723|reactome:R-HSA-6785807|reactome:R-HSA-8986944 refseq:NP_055578.2|rcsb pdb:7ODR|rcsb pdb:7ODS|rcsb pdb:7ODT|rcsb pdb:7OF0|rcsb pdb:7OF2|rcsb pdb:7OF3|rcsb pdb:7OF4|rcsb pdb:7OF5|rcsb pdb:7OF6|rcsb pdb:7OF7|rcsb pdb:7OG4|reactome:R-HSA-5368286|reactome:R-HSA-5389840|reactome:R-HSA-5419276|rcsb pdb:7O9M|ensembl:ENSG00000115364(gene)|ensembl:ENST00000393909(transcript)|ensembl:ENST00000409374(transcript)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005634"(nucleus)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005762"(mitochondrial large ribosomal subunit)|go:"GO:0006412"(translation)|interpro:IPR001857(Ribosomal protein L19)|interpro:IPR008991(Translation protein SH3-like)|interpro:IPR038657|mint:P49406|rcsb pdb:3J7Y|rcsb pdb:3J9M|rcsb pdb:5OOL|rcsb pdb:5OOM|rcsb pdb:6I9R|rcsb pdb:6NU2|rcsb pdb:6NU3|rcsb pdb:6VLZ|rcsb pdb:6VMI|rcsb pdb:6ZM5|rcsb pdb:6ZM6|rcsb pdb:6ZS9|rcsb pdb:6ZSA|rcsb pdb:6ZSB|rcsb pdb:6ZSC|rcsb pdb:6ZSD|rcsb pdb:6ZSE|rcsb pdb:6ZSG|rcsb pdb:7A5F|rcsb pdb:7A5G|rcsb pdb:7A5H|rcsb pdb:7A5I|rcsb pdb:7A5J|rcsb pdb:7A5K|rcsb pdb:7L08|rcsb pdb:7L20|rcsb pdb:7O9K go:"GO:0005634"(nucleus) - - figure legend:ST2 F2A|comment:proteins identified only in our induced samples in three MudPIT analyses with the more stringent BY-adjusted significance p<0.05|dataset:Brain Disease - Neurological Diseases & Disorders|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-daoy)|taxid:9606(Homo sapiens DAOY cerebellar medulloblastoma cell line) - 2020/12/29 2020/12/29 rogid:cn8gYfKDpQc8J2ygnqny32sIyyU9606 rogid:4ZCZpq3u9wkdpuNVFpk+bhceaW09606 rigid:6EMs5+B89Q89RCR/2S2BG6PhH9E false tandem tag:n-n - - - psi-mi:"MI:0658"(multidimensional protein identification technology) psi-mi:"MI:0658"(multidimensional protein identification technology) uniprotkb:P48431 uniprotkb:Q96DH6 intact:EBI-6124081|uniprotkb:Q14537|ensembl:ENSP00000323588 intact:EBI-2462339|uniprotkb:Q7Z6M7|uniprotkb:Q8N9T4|ensembl:ENSP00000284073|ensembl:ENSP00000502137 psi-mi:sox2_human(display_long)|uniprotkb:SOX2(gene name)|psi-mi:SOX2(display_short) psi-mi:msi2h_human(display_long)|uniprotkb:MSI2(gene name)|psi-mi:MSI2(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Cox et al. (2012) pubmed:23667531|imex:IM-28599 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-26574619|imex:IM-28599-5 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_003097.1|dip:DIP-59913N|ensembl:ENSG00000181449(gene)|ensembl:ENST00000325404(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001649"(osteoblast differentiation)|go:"GO:0001654"(eye development)|go:"GO:0001714"(endodermal cell fate specification)|go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006325"(chromatin organization)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0009611"(response to wounding)|go:"GO:0009653"(anatomical structure morphogenesis)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0021781"(glial cell fate commitment)|go:"GO:0021983"(pituitary gland development)|go:"GO:0021984"(adenohypophysis development)|go:"GO:0022409"(positive regulation of cell-cell adhesion)|go:"GO:0030154"(cell differentiation)|go:"GO:0030900"(forebrain development)|go:"GO:0035019"(somatic stem cell population maintenance)|go:"GO:0035198"(miRNA binding)|go:"GO:0042246"(tissue regeneration)|go:"GO:0043281"(regulation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0043410"(positive regulation of MAPK cascade)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045165"(cell fate commitment)|go:"GO:0045597"(positive regulation of cell differentiation)|go:"GO:0045665"(negative regulation of neuron differentiation)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048839"(inner ear development)|go:"GO:0050680"(negative regulation of epithelial cell proliferation)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0070848"(response to growth factor)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:0097150"(neuronal stem cell population maintenance)|interpro:IPR009071(High mobility group box, HMG)|interpro:IPR022097|interpro:IPR032643|interpro:IPR036910|mint:P48431|rcsb pdb:1O4X|rcsb pdb:2LE4|rcsb pdb:6T7B|rcsb pdb:6T90|rcsb pdb:6WX7|rcsb pdb:6WX8|rcsb pdb:6WX9|rcsb pdb:6YOV|reactome:R-HSA-2892245|reactome:R-HSA-2892247|reactome:R-HSA-3769402|reactome:R-HSA-452723|reactome:R-HSA-6785807|reactome:R-HSA-8986944 refseq:NP_620412.1|refseq:NP_733839.1|ensembl:ENSG00000153944(gene)|ensembl:ENST00000284073(transcript)|ensembl:ENST00000674964(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005844"(polysome)|go:"GO:0008266"("poly(U) RNA binding")|go:"GO:0042802"(identical protein binding)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0048864"(stem cell development)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR034126|interpro:IPR034130|interpro:IPR035979|mint:Q96DH6|rcsb pdb:6C8U|rcsb pdb:6DBP|rcsb pdb:6NTY|reactome:R-HSA-9013418 go:"GO:0005634"(nucleus) - - figure legend:ST2 F2A|comment:proteins identified only in our induced samples in three MudPIT analyses with the more stringent BY-adjusted significance p<0.05|dataset:Brain Disease - Neurological Diseases & Disorders|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-daoy)|taxid:9606(Homo sapiens DAOY cerebellar medulloblastoma cell line) - 2020/12/29 2020/12/29 rogid:cn8gYfKDpQc8J2ygnqny32sIyyU9606 rogid:/tSHeNbYwUTw4kGlF3LQw+5OVjs9606 rigid:6EMs5+B89Q89RCR/2S2BG6PhH9E false tandem tag:n-n - - - psi-mi:"MI:0658"(multidimensional protein identification technology) psi-mi:"MI:0658"(multidimensional protein identification technology) uniprotkb:P48431 uniprotkb:P40425 intact:EBI-6124081|uniprotkb:Q14537|ensembl:ENSP00000323588 intact:EBI-348489|ensembl:ENSP00000372757|ensembl:ENSP00000390009|ensembl:ENSP00000391745|ensembl:ENSP00000397177|ensembl:ENSP00000403948|ensembl:ENSP00000410710|ensembl:ENSP00000364190|uniprotkb:A2BFJ2 psi-mi:sox2_human(display_long)|uniprotkb:SOX2(gene name)|psi-mi:SOX2(display_short) psi-mi:pbx2_human(display_long)|uniprotkb:PBX2(gene name)|psi-mi:PBX2(display_short)|uniprotkb:G17(gene name synonym)|uniprotkb:Homeobox protein PBX2(gene name synonym)|uniprotkb:Protein G17(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Cox et al. (2012) pubmed:23667531|imex:IM-28599 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-26574619|imex:IM-28599-5 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_003097.1|dip:DIP-59913N|ensembl:ENSG00000181449(gene)|ensembl:ENST00000325404(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001649"(osteoblast differentiation)|go:"GO:0001654"(eye development)|go:"GO:0001714"(endodermal cell fate specification)|go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006325"(chromatin organization)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0009611"(response to wounding)|go:"GO:0009653"(anatomical structure morphogenesis)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0021781"(glial cell fate commitment)|go:"GO:0021983"(pituitary gland development)|go:"GO:0021984"(adenohypophysis development)|go:"GO:0022409"(positive regulation of cell-cell adhesion)|go:"GO:0030154"(cell differentiation)|go:"GO:0030900"(forebrain development)|go:"GO:0035019"(somatic stem cell population maintenance)|go:"GO:0035198"(miRNA binding)|go:"GO:0042246"(tissue regeneration)|go:"GO:0043281"(regulation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0043410"(positive regulation of MAPK cascade)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045165"(cell fate commitment)|go:"GO:0045597"(positive regulation of cell differentiation)|go:"GO:0045665"(negative regulation of neuron differentiation)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048839"(inner ear development)|go:"GO:0050680"(negative regulation of epithelial cell proliferation)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0070848"(response to growth factor)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:0097150"(neuronal stem cell population maintenance)|interpro:IPR009071(High mobility group box, HMG)|interpro:IPR022097|interpro:IPR032643|interpro:IPR036910|mint:P48431|rcsb pdb:1O4X|rcsb pdb:2LE4|rcsb pdb:6T7B|rcsb pdb:6T90|rcsb pdb:6WX7|rcsb pdb:6WX8|rcsb pdb:6WX9|rcsb pdb:6YOV|reactome:R-HSA-2892245|reactome:R-HSA-2892247|reactome:R-HSA-3769402|reactome:R-HSA-452723|reactome:R-HSA-6785807|reactome:R-HSA-8986944 refseq:NP_002577.2|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001654"(eye development)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|ensembl:ENST00000375050(transcript)|ensembl:ENST00000383270(transcript)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007420"(brain development)|go:"GO:0008134"(transcription factor binding)|go:"GO:0009887"(animal organ morphogenesis)|go:"GO:0009954"(proximal/distal pattern formation)|go:"GO:0030326"(embryonic limb morphogenesis)|ensembl:ENST00000420432(transcript)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048568"(embryonic organ development)|ensembl:ENST00000431537(transcript)|ensembl:ENST00000433552(transcript)|ensembl:ENST00000453487(transcript)|ensembl:ENST00000453961(transcript)|go:"GO:0000785"(chromatin)|interpro:IPR001356(Homeobox)|interpro:IPR005542(PBX)|interpro:IPR009057(Homeodomain-like)|interpro:IPR017970|mint:P40425|go:"GO:0048666"(neuron development)|ensembl:ENSG00000204304(gene)|ensembl:ENSG00000206315(gene)|ensembl:ENSG00000224952(gene)|ensembl:ENSG00000225987(gene)|ensembl:ENSG00000232005(gene)|ensembl:ENSG00000236353(gene)|ensembl:ENSG00000237344(gene) go:"GO:0005634"(nucleus) - - figure legend:ST2 F2A|comment:proteins identified only in our induced samples in three MudPIT analyses with the more stringent BY-adjusted significance p<0.05|dataset:Brain Disease - Neurological Diseases & Disorders|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-daoy)|taxid:9606(Homo sapiens DAOY cerebellar medulloblastoma cell line) - 2020/12/29 2020/12/29 rogid:cn8gYfKDpQc8J2ygnqny32sIyyU9606 rogid:HvGKE7Hqw9Ed2yFQkYoIutQdBpE9606 rigid:6EMs5+B89Q89RCR/2S2BG6PhH9E false tandem tag:n-n - - - psi-mi:"MI:0658"(multidimensional protein identification technology) psi-mi:"MI:0658"(multidimensional protein identification technology) uniprotkb:P48431 uniprotkb:O15350 intact:EBI-6124081|uniprotkb:Q14537|ensembl:ENSP00000323588 intact:EBI-389606|uniprotkb:O15351|uniprotkb:Q17RN8|uniprotkb:Q5TBV5|uniprotkb:Q5TBV6|uniprotkb:Q8NHW9|uniprotkb:Q8TDY5|uniprotkb:Q8TDY6|uniprotkb:Q9NTK8|uniprotkb:B7Z9C1|uniprotkb:B7Z8Z1|uniprotkb:C9J521|uniprotkb:B7Z7J4|ensembl:ENSP00000367545 psi-mi:sox2_human(display_long)|uniprotkb:SOX2(gene name)|psi-mi:SOX2(display_short) psi-mi:p73_human(display_long)|uniprotkb:TP73(gene name)|psi-mi:TP73(display_short)|uniprotkb:P73(gene name synonym)|uniprotkb:p53-like transcription factor(gene name synonym)|uniprotkb:p53-related protein(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Cox et al. (2012) pubmed:23667531|imex:IM-28599 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-26574619|imex:IM-28599-5 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_003097.1|dip:DIP-59913N|ensembl:ENSG00000181449(gene)|ensembl:ENST00000325404(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001649"(osteoblast differentiation)|go:"GO:0001654"(eye development)|go:"GO:0001714"(endodermal cell fate specification)|go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006325"(chromatin organization)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0009611"(response to wounding)|go:"GO:0009653"(anatomical structure morphogenesis)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0021781"(glial cell fate commitment)|go:"GO:0021983"(pituitary gland development)|go:"GO:0021984"(adenohypophysis development)|go:"GO:0022409"(positive regulation of cell-cell adhesion)|go:"GO:0030154"(cell differentiation)|go:"GO:0030900"(forebrain development)|go:"GO:0035019"(somatic stem cell population maintenance)|go:"GO:0035198"(miRNA binding)|go:"GO:0042246"(tissue regeneration)|go:"GO:0043281"(regulation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0043410"(positive regulation of MAPK cascade)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045165"(cell fate commitment)|go:"GO:0045597"(positive regulation of cell differentiation)|go:"GO:0045665"(negative regulation of neuron differentiation)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048839"(inner ear development)|go:"GO:0050680"(negative regulation of epithelial cell proliferation)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0070848"(response to growth factor)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:0097150"(neuronal stem cell population maintenance)|interpro:IPR009071(High mobility group box, HMG)|interpro:IPR022097|interpro:IPR032643|interpro:IPR036910|mint:P48431|rcsb pdb:1O4X|rcsb pdb:2LE4|rcsb pdb:6T7B|rcsb pdb:6T90|rcsb pdb:6WX7|rcsb pdb:6WX8|rcsb pdb:6WX9|rcsb pdb:6YOV|reactome:R-HSA-2892245|reactome:R-HSA-2892247|reactome:R-HSA-3769402|reactome:R-HSA-452723|reactome:R-HSA-6785807|reactome:R-HSA-8986944 ensembl:ENST00000346387|ensembl:ENSP00000340740|ensembl:ENST00000354437|ensembl:ENSP00000346423|ensembl:ENST00000357733|ensembl:ENSP00000350366|ensembl:ENST00000378285|ensembl:ENSP00000367534|ensembl:ENST00000378288|ensembl:ENSP00000367537|ensembl:ENST00000378290|ensembl:ENSP00000367539|ensembl:ENSP00000367545|ensembl:ENST00000603362|ensembl:ENSP00000474626|ensembl:ENST00000604074|ensembl:ENSP00000475143|ensembl:ENST00000604479|ensembl:ENSP00000474322|refseq:NP_001119712.1|refseq:NP_001119713.1|refseq:NP_001119714.1|refseq:NP_001191113.1|refseq:NP_001191114.1|refseq:NP_001191115.1|refseq:NP_001191117.1|refseq:NP_001191118.1|refseq:NP_001191119.1|refseq:NP_001191120.1|refseq:NP_005418.1|refseq:NP_001191121.1|refseq:NP_001191116.1|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0007049"(cell cycle)|go:"GO:0007346"(regulation of mitotic cell cycle)|go:"GO:0008134"(transcription factor binding)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0008630"(intrinsic apoptotic signaling pathway in response to DNA damage)|go:"GO:0010243"(response to organonitrogen compound)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030054"(cell junction)|go:"GO:0042493"|go:"GO:0042771"(intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator)|go:"GO:0042802"(identical protein binding)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0045665"(negative regulation of neuron differentiation)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|go:"GO:0048714"(positive regulation of oligodendrocyte differentiation)|ensembl:ENSG00000078900(gene)|ensembl:ENST00000378295(transcript)|go:"GO:0000187"(obsolete activation of MAPK activity)|go:"GO:0000785"(chromatin)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001822"(kidney development)|go:"GO:0002039"(p53 binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0006298"(mismatch repair)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0051262"(protein tetramerization)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0060044"(negative regulation of cardiac muscle cell proliferation)|go:"GO:0097371"(MDM2/MDM4 family protein binding)|go:"GO:0140297"(DNA-binding transcription factor binding)|interpro:IPR001660(Sterile alpha motif SAM)|interpro:IPR002117(p53 tumor antigen)|interpro:IPR008967(p53-like transcription factor, DNA-binding)|interpro:IPR010991(p53, tetramerisation)|interpro:IPR011615(p53, DNA-binding)|interpro:IPR012346(p53 and RUNT-type transcription factor, DNA-binding)|interpro:IPR013761(Sterile alpha motif-type)|interpro:IPR032646|interpro:IPR036674|interpro:IPR037612|mint:O15350|rcsb pdb:1COK|rcsb pdb:1DXS|rcsb pdb:2KBY|rcsb pdb:2MPS|rcsb pdb:2NB1|rcsb pdb:2WQI|rcsb pdb:2WQJ|rcsb pdb:2WTT|rcsb pdb:2XWC|rcsb pdb:3VD0|rcsb pdb:3VD1|rcsb pdb:3VD2|rcsb pdb:4A63|rcsb pdb:4G82|rcsb pdb:4G83|rcsb pdb:4GUO|rcsb pdb:4GUQ|rcsb pdb:5HOB|rcsb pdb:5HOC|rcsb pdb:5KBD|rcsb pdb:6FGS|rcsb pdb:6IJQ|reactome:R-HSA-139915|reactome:R-HSA-6803204|reactome:R-HSA-6803205|reactome:R-HSA-6803207|reactome:R-HSA-6803211|reactome:R-HSA-6804759|reactome:R-HSA-8939236|dip:DIP-24202N go:"GO:0005634"(nucleus) - - figure legend:ST2 F2A|comment:proteins identified only in our induced samples in three MudPIT analyses with the more stringent BY-adjusted significance p<0.05|dataset:Brain Disease - Neurological Diseases & Disorders|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-daoy)|taxid:9606(Homo sapiens DAOY cerebellar medulloblastoma cell line) - 2020/12/29 2020/12/29 rogid:cn8gYfKDpQc8J2ygnqny32sIyyU9606 rogid:KwI8l1a8t8GHsZwMDi4v2bqwe0c9606 rigid:6EMs5+B89Q89RCR/2S2BG6PhH9E false tandem tag:n-n - - - psi-mi:"MI:0658"(multidimensional protein identification technology) psi-mi:"MI:0658"(multidimensional protein identification technology) uniprotkb:P48431 uniprotkb:P35226 intact:EBI-6124081|uniprotkb:Q14537|ensembl:ENSP00000323588 intact:EBI-2341576|uniprotkb:Q5T8Z3|uniprotkb:Q96F37|uniprotkb:Q16030|intact:EBI-28989037|ensembl:ENSP00000365851 psi-mi:sox2_human(display_long)|uniprotkb:SOX2(gene name)|psi-mi:SOX2(display_short) psi-mi:bmi1_human(display_long)|uniprotkb:BMI1(gene name)|psi-mi:BMI1(display_short)|uniprotkb:PCGF4(gene name synonym)|uniprotkb:RNF51(gene name synonym)|uniprotkb:Polycomb group RING finger protein 4(gene name synonym)|uniprotkb:RING finger protein 51(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Cox et al. (2012) pubmed:23667531|imex:IM-28599 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-26574619|imex:IM-28599-5 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_003097.1|dip:DIP-59913N|ensembl:ENSG00000181449(gene)|ensembl:ENST00000325404(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001649"(osteoblast differentiation)|go:"GO:0001654"(eye development)|go:"GO:0001714"(endodermal cell fate specification)|go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006325"(chromatin organization)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0009611"(response to wounding)|go:"GO:0009653"(anatomical structure morphogenesis)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0021781"(glial cell fate commitment)|go:"GO:0021983"(pituitary gland development)|go:"GO:0021984"(adenohypophysis development)|go:"GO:0022409"(positive regulation of cell-cell adhesion)|go:"GO:0030154"(cell differentiation)|go:"GO:0030900"(forebrain development)|go:"GO:0035019"(somatic stem cell population maintenance)|go:"GO:0035198"(miRNA binding)|go:"GO:0042246"(tissue regeneration)|go:"GO:0043281"(regulation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0043410"(positive regulation of MAPK cascade)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045165"(cell fate commitment)|go:"GO:0045597"(positive regulation of cell differentiation)|go:"GO:0045665"(negative regulation of neuron differentiation)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048839"(inner ear development)|go:"GO:0050680"(negative regulation of epithelial cell proliferation)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0070848"(response to growth factor)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:0097150"(neuronal stem cell population maintenance)|interpro:IPR009071(High mobility group box, HMG)|interpro:IPR022097|interpro:IPR032643|interpro:IPR036910|mint:P48431|rcsb pdb:1O4X|rcsb pdb:2LE4|rcsb pdb:6T7B|rcsb pdb:6T90|rcsb pdb:6WX7|rcsb pdb:6WX8|rcsb pdb:6WX9|rcsb pdb:6YOV|reactome:R-HSA-2892245|reactome:R-HSA-2892247|reactome:R-HSA-3769402|reactome:R-HSA-452723|reactome:R-HSA-6785807|reactome:R-HSA-8986944 refseq:NP_001190991.1|refseq:NP_005171.4|ensembl:ENSP00000365851|dip:DIP-41879N|ensembl:ENSG00000168283(gene)|ensembl:ENST00000376663(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0000792"(heterochromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006306"(DNA methylation)|go:"GO:0006342"|go:"GO:0006959"(humoral immune response)|go:"GO:0007379"(segment specification)|go:"GO:0007420"(brain development)|go:"GO:0008270"(zinc ion binding)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0016573"(histone acetylation)|go:"GO:0016604"(nuclear body)|go:"GO:0021903"(rostrocaudal neural tube patterning)|go:"GO:0030097"(hemopoiesis)|go:"GO:0030890"(positive regulation of B cell proliferation)|go:"GO:0031519"(PcG protein complex)|go:"GO:0033092"(positive regulation of immature T cell proliferation in thymus)|go:"GO:0035102"(PRC1 complex)|go:"GO:0036353"(histone H2A-K119 monoubiquitination)|go:"GO:0045814"(negative regulation of gene expression, epigenetic)|go:"GO:0048103"(somatic stem cell division)|go:"GO:0048146"(positive regulation of fibroblast proliferation)|go:"GO:0048704"(embryonic skeletal system morphogenesis)|go:"GO:0051443"(positive regulation of ubiquitin-protein transferase activity)|go:"GO:0071347"(cellular response to interleukin-1)|go:"GO:0071535"(RING-like zinc finger domain binding)|go:"GO:0071549"(cellular response to dexamethasone stimulus)|go:"GO:0097027"(ubiquitin-protein transferase activator activity)|go:"GO:1990841"(promoter-specific chromatin binding)|go:"GO:2000011"(regulation of adaxial/abaxial pattern formation)|go:"GO:2001234"(negative regulation of apoptotic signaling pathway)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017907|interpro:IPR032443|mint:P35226|rcsb pdb:2H0D|rcsb pdb:2NA1|rcsb pdb:3RPG|rcsb pdb:4R8P|rcsb pdb:5FR6|rcsb pdb:6WI7|rcsb pdb:6WI8|rcsb pdb:7ND1|reactome:R-HSA-2559580|reactome:R-HSA-3108214|reactome:R-HSA-3899300|reactome:R-HSA-4551638|reactome:R-HSA-4570464|reactome:R-HSA-4655427|reactome:R-HSA-8939243|reactome:R-HSA-8943724|reactome:R-HSA-8953750 go:"GO:0005634"(nucleus) - - figure legend:ST2 F2A|comment:proteins identified only in our induced samples in three MudPIT analyses with the more stringent BY-adjusted significance p<0.05|dataset:Brain Disease - Neurological Diseases & Disorders|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-daoy)|taxid:9606(Homo sapiens DAOY cerebellar medulloblastoma cell line) - 2020/12/29 2020/12/29 rogid:cn8gYfKDpQc8J2ygnqny32sIyyU9606 rogid:ruyez2gHfd/si8gxYUDZzZ1L4689606 rigid:6EMs5+B89Q89RCR/2S2BG6PhH9E false tandem tag:n-n - - - psi-mi:"MI:0658"(multidimensional protein identification technology) psi-mi:"MI:0658"(multidimensional protein identification technology) uniprotkb:P48431 uniprotkb:Q8N108 intact:EBI-6124081|uniprotkb:Q14537|ensembl:ENSP00000323588 intact:EBI-3504940|uniprotkb:Q5T104|uniprotkb:Q6AHY8|uniprotkb:Q86TB4|uniprotkb:Q8N156|uniprotkb:Q8N161|uniprotkb:Q8NC37|uniprotkb:Q8NES4|uniprotkb:Q8NES5|uniprotkb:Q8NES6|uniprotkb:Q8WWG2|uniprotkb:Q9HCG2|uniprotkb:Q08AE0|uniprotkb:Q5TAD5|uniprotkb:C9JFD4|uniprotkb:Q32NC4|uniprotkb:Q5TAD2|uniprotkb:Q5TAD4|ensembl:ENSP00000347514|uniprotkb:Q5TAD1 psi-mi:sox2_human(display_long)|uniprotkb:SOX2(gene name)|psi-mi:SOX2(display_short) psi-mi:mier1_human(display_long)|uniprotkb:MIER1(gene name)|psi-mi:MIER1(display_short)|uniprotkb:KIAA1610(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Cox et al. (2012) pubmed:23667531|imex:IM-28599 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-26574619|imex:IM-28599-5 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_003097.1|dip:DIP-59913N|ensembl:ENSG00000181449(gene)|ensembl:ENST00000325404(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001649"(osteoblast differentiation)|go:"GO:0001654"(eye development)|go:"GO:0001714"(endodermal cell fate specification)|go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006325"(chromatin organization)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0009611"(response to wounding)|go:"GO:0009653"(anatomical structure morphogenesis)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0021781"(glial cell fate commitment)|go:"GO:0021983"(pituitary gland development)|go:"GO:0021984"(adenohypophysis development)|go:"GO:0022409"(positive regulation of cell-cell adhesion)|go:"GO:0030154"(cell differentiation)|go:"GO:0030900"(forebrain development)|go:"GO:0035019"(somatic stem cell population maintenance)|go:"GO:0035198"(miRNA binding)|go:"GO:0042246"(tissue regeneration)|go:"GO:0043281"(regulation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0043410"(positive regulation of MAPK cascade)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045165"(cell fate commitment)|go:"GO:0045597"(positive regulation of cell differentiation)|go:"GO:0045665"(negative regulation of neuron differentiation)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048839"(inner ear development)|go:"GO:0050680"(negative regulation of epithelial cell proliferation)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0070848"(response to growth factor)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:0097150"(neuronal stem cell population maintenance)|interpro:IPR009071(High mobility group box, HMG)|interpro:IPR022097|interpro:IPR032643|interpro:IPR036910|mint:P48431|rcsb pdb:1O4X|rcsb pdb:2LE4|rcsb pdb:6T7B|rcsb pdb:6T90|rcsb pdb:6WX7|rcsb pdb:6WX8|rcsb pdb:6WX9|rcsb pdb:6YOV|reactome:R-HSA-2892245|reactome:R-HSA-2892247|reactome:R-HSA-3769402|reactome:R-HSA-452723|reactome:R-HSA-6785807|reactome:R-HSA-8986944 refseq:NP_001071169.1|refseq:NP_001071170.2|refseq:NP_001071171.2|refseq:NP_001071172.1|refseq:NP_001139582.1|refseq:NP_001139584.1|refseq:NP_065999.2|refseq:NP_001265144.1|refseq:NP_001071168.2|refseq:NP_001139583.1|refseq:NP_001139585.1|ensembl:ENSG00000198160(gene)|ensembl:ENST00000355356(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0016575"(histone deacetylation)|go:"GO:0017053"(transcription repressor complex)|go:"GO:0031937"(obsolete positive regulation of chromatin silencing)|go:"GO:0032991"(protein-containing complex)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|interpro:IPR000949(ELM2)|interpro:IPR001005(SANT, DNA-binding)|interpro:IPR009057(Homeodomain-like)|interpro:IPR017884|interpro:IPR017930|interpro:IPR031169|interpro:IPR040138|mint:Q8N108|refseq:XP_005271133.1|refseq:XP_016857413.1|refseq:XP_016857414.1|refseq:XP_016857415.1|refseq:XP_016857416.1|refseq:XP_016857417.1|refseq:XP_016857420.1 go:"GO:0005634"(nucleus) - - figure legend:ST2 F2A|comment:proteins identified only in our induced samples in three MudPIT analyses with the more stringent BY-adjusted significance p<0.05|dataset:Brain Disease - Neurological Diseases & Disorders|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-daoy)|taxid:9606(Homo sapiens DAOY cerebellar medulloblastoma cell line) - 2020/12/29 2020/12/29 rogid:cn8gYfKDpQc8J2ygnqny32sIyyU9606 rogid:5WJANc4uv5fXG+0evX3ApSunJJE9606 rigid:6EMs5+B89Q89RCR/2S2BG6PhH9E false tandem tag:n-n - - - psi-mi:"MI:0658"(multidimensional protein identification technology) psi-mi:"MI:0658"(multidimensional protein identification technology) uniprotkb:P48431 uniprotkb:Q8NEA6 intact:EBI-6124081|uniprotkb:Q14537|ensembl:ENSP00000323588 intact:EBI-744456|uniprotkb:B1AL19|uniprotkb:Q1PHK5|ensembl:ENSP00000325494|ensembl:ENSP00000507306 psi-mi:sox2_human(display_long)|uniprotkb:SOX2(gene name)|psi-mi:SOX2(display_short) psi-mi:glis3_human(display_long)|uniprotkb:GLI-similar 3(gene name synonym)|uniprotkb:Zinc finger protein 515(gene name synonym)|uniprotkb:GLIS3(gene name)|psi-mi:GLIS3(display_short)|uniprotkb:ZNF515(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Cox et al. (2012) pubmed:23667531|imex:IM-28599 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-26574619|imex:IM-28599-5 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_003097.1|dip:DIP-59913N|ensembl:ENSG00000181449(gene)|ensembl:ENST00000325404(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001649"(osteoblast differentiation)|go:"GO:0001654"(eye development)|go:"GO:0001714"(endodermal cell fate specification)|go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006325"(chromatin organization)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0009611"(response to wounding)|go:"GO:0009653"(anatomical structure morphogenesis)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0021781"(glial cell fate commitment)|go:"GO:0021983"(pituitary gland development)|go:"GO:0021984"(adenohypophysis development)|go:"GO:0022409"(positive regulation of cell-cell adhesion)|go:"GO:0030154"(cell differentiation)|go:"GO:0030900"(forebrain development)|go:"GO:0035019"(somatic stem cell population maintenance)|go:"GO:0035198"(miRNA binding)|go:"GO:0042246"(tissue regeneration)|go:"GO:0043281"(regulation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0043410"(positive regulation of MAPK cascade)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045165"(cell fate commitment)|go:"GO:0045597"(positive regulation of cell differentiation)|go:"GO:0045665"(negative regulation of neuron differentiation)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048839"(inner ear development)|go:"GO:0050680"(negative regulation of epithelial cell proliferation)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0070848"(response to growth factor)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:0097150"(neuronal stem cell population maintenance)|interpro:IPR009071(High mobility group box, HMG)|interpro:IPR022097|interpro:IPR032643|interpro:IPR036910|mint:P48431|rcsb pdb:1O4X|rcsb pdb:2LE4|rcsb pdb:6T7B|rcsb pdb:6T90|rcsb pdb:6WX7|rcsb pdb:6WX8|rcsb pdb:6WX9|rcsb pdb:6YOV|reactome:R-HSA-2892245|reactome:R-HSA-2892247|reactome:R-HSA-3769402|reactome:R-HSA-452723|reactome:R-HSA-6785807|reactome:R-HSA-8986944 refseq:NP_001035878.1|refseq:NP_689842.3|refseq:XP_011516065.1|refseq:XP_011516066.1|refseq:XP_011516068.1|ensembl:ENSP00000325494|ensembl:ENST00000381971|ensembl:ENSP00000371398|ensembl:ENSP00000507306|refseq:XP_005251443.1|ensembl:ENSG00000107249(gene)|ensembl:ENST00000324333(transcript)|ensembl:ENST00000682749(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR030405|interpro:IPR036236|interpro:IPR043359|mint:Q8NEA6|refseq:XP_016869850.1 go:"GO:0005634"(nucleus) - - figure legend:ST2 F2A|comment:proteins identified only in our induced samples in three MudPIT analyses with the more stringent BY-adjusted significance p<0.05|dataset:Brain Disease - Neurological Diseases & Disorders|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-daoy)|taxid:9606(Homo sapiens DAOY cerebellar medulloblastoma cell line) - 2020/12/29 2020/12/29 rogid:cn8gYfKDpQc8J2ygnqny32sIyyU9606 rogid:Lw/ndmcKfz+wO+0eEheRj4Y0fXM9606 rigid:6EMs5+B89Q89RCR/2S2BG6PhH9E false tandem tag:n-n - - - psi-mi:"MI:0658"(multidimensional protein identification technology) psi-mi:"MI:0658"(multidimensional protein identification technology) uniprotkb:P48431 uniprotkb:O15119 intact:EBI-6124081|uniprotkb:Q14537|ensembl:ENSP00000323588 intact:EBI-3452216|uniprotkb:Q9UKF8|uniprotkb:Q8TB20|ensembl:ENSP00000257566 psi-mi:sox2_human(display_long)|uniprotkb:SOX2(gene name)|psi-mi:SOX2(display_short) psi-mi:tbx3_human(display_long)|uniprotkb:TBX3(gene name)|psi-mi:TBX3(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Cox et al. (2012) pubmed:23667531|imex:IM-28599 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-26574619|imex:IM-28599-5 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_003097.1|dip:DIP-59913N|ensembl:ENSG00000181449(gene)|ensembl:ENST00000325404(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001649"(osteoblast differentiation)|go:"GO:0001654"(eye development)|go:"GO:0001714"(endodermal cell fate specification)|go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006325"(chromatin organization)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0009611"(response to wounding)|go:"GO:0009653"(anatomical structure morphogenesis)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0021781"(glial cell fate commitment)|go:"GO:0021983"(pituitary gland development)|go:"GO:0021984"(adenohypophysis development)|go:"GO:0022409"(positive regulation of cell-cell adhesion)|go:"GO:0030154"(cell differentiation)|go:"GO:0030900"(forebrain development)|go:"GO:0035019"(somatic stem cell population maintenance)|go:"GO:0035198"(miRNA binding)|go:"GO:0042246"(tissue regeneration)|go:"GO:0043281"(regulation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0043410"(positive regulation of MAPK cascade)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045165"(cell fate commitment)|go:"GO:0045597"(positive regulation of cell differentiation)|go:"GO:0045665"(negative regulation of neuron differentiation)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048839"(inner ear development)|go:"GO:0050680"(negative regulation of epithelial cell proliferation)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0070848"(response to growth factor)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:0097150"(neuronal stem cell population maintenance)|interpro:IPR009071(High mobility group box, HMG)|interpro:IPR022097|interpro:IPR032643|interpro:IPR036910|mint:P48431|rcsb pdb:1O4X|rcsb pdb:2LE4|rcsb pdb:6T7B|rcsb pdb:6T90|rcsb pdb:6WX7|rcsb pdb:6WX8|rcsb pdb:6WX9|rcsb pdb:6YOV|reactome:R-HSA-2892245|reactome:R-HSA-2892247|reactome:R-HSA-3769402|reactome:R-HSA-452723|reactome:R-HSA-6785807|reactome:R-HSA-8986944 refseq:NP_005987.3|refseq:NP_057653.3|go:"GO:0051145"(smooth muscle cell differentiation)|go:"GO:0060021"(roof of mouth development)|go:"GO:0035115"(embryonic forelimb morphogenesis)|go:"GO:0035116"(embryonic hindlimb morphogenesis)|go:"GO:0060317"(cardiac epithelial to mesenchymal transition)|go:"GO:0060412"(ventricular septum morphogenesis)|go:"GO:0035136"(forelimb morphogenesis)|go:"GO:0060444"(branching involved in mammary gland duct morphogenesis)|go:"GO:0060596"(mammary placode formation)|go:"GO:0060923"(cardiac muscle cell fate commitment)|go:"GO:0036302"(atrioventricular canal development)|go:"GO:0060931"(sinoatrial node cell development)|go:"GO:0042733"(embryonic digit morphogenesis)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:0072105"(ureteric peristalsis)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0090398"(cellular senescence)|go:"GO:0045662"(negative regulation of myoblast differentiation)|go:"GO:1905072"(cardiac jelly development)|go:"GO:1905222"(atrioventricular canal morphogenesis)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|go:"GO:0045787"(positive regulation of cell cycle)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:2000137"(negative regulation of cell proliferation involved in heart morphogenesis)|go:"GO:2000648"(positive regulation of stem cell proliferation)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|interpro:IPR001699(Transcription factor, T-box)|interpro:IPR008967(p53-like transcription factor, DNA-binding)|interpro:IPR018186|interpro:IPR022582|go:"GO:0046884"(follicle-stimulating hormone secretion)|interpro:IPR036960|mint:O15119|rcsb pdb:1H6F|go:"GO:0048332"(mesoderm morphogenesis)|ensembl:ENSG00000135111(gene)|ensembl:ENST00000257566(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001501"(skeletal system development)|go:"GO:0001568"(blood vessel development)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0001708"(cell fate specification)|go:"GO:0001947"(heart looping)|go:"GO:0003151"(outflow tract morphogenesis)|go:"GO:0003167"(atrioventricular bundle cell differentiation)|go:"GO:0003205"(cardiac chamber development)|go:"GO:0003272"(endocardial cushion formation)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007417"(central nervous system development)|go:"GO:0007569"(cell aging)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0008595"(anterior/posterior axis specification, embryo)|go:"GO:0009887"(animal organ morphogenesis)|go:"GO:0010159"(specification of animal organ position)|go:"GO:0019827"(stem cell population maintenance)|go:"GO:0021761"(limbic system development)|go:"GO:0030539"(male genitalia development)|go:"GO:0030540"(female genitalia development)|go:"GO:0030857"(negative regulation of epithelial cell differentiation)|go:"GO:0030879"(mammary gland development)|go:"GO:0032275"(luteinizing hormone secretion) go:"GO:0005634"(nucleus) - - figure legend:ST2 F2A|comment:proteins identified only in our induced samples in three MudPIT analyses with the more stringent BY-adjusted significance p<0.05|dataset:Brain Disease - Neurological Diseases & Disorders|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-daoy)|taxid:9606(Homo sapiens DAOY cerebellar medulloblastoma cell line) - 2020/12/29 2020/12/29 rogid:cn8gYfKDpQc8J2ygnqny32sIyyU9606 rogid:XFc+uKzh/fepV1LnuCMXgShOuj49606 rigid:6EMs5+B89Q89RCR/2S2BG6PhH9E false tandem tag:n-n - - - psi-mi:"MI:0658"(multidimensional protein identification technology) psi-mi:"MI:0658"(multidimensional protein identification technology) uniprotkb:P48431 uniprotkb:Q08380 intact:EBI-6124081|uniprotkb:Q14537|ensembl:ENSP00000323588 intact:EBI-354956|ensembl:ENSP00000262776|uniprotkb:Q7M4S0|uniprotkb:Q9UCH8|uniprotkb:Q9UCH9|uniprotkb:Q9UCI0 psi-mi:sox2_human(display_long)|uniprotkb:SOX2(gene name)|psi-mi:SOX2(display_short) psi-mi:lg3bp_human(display_long)|uniprotkb:LGALS3BP(gene name)|psi-mi:LGALS3BP(display_short)|uniprotkb:M2BP(gene name synonym)|uniprotkb:Lectin galactoside-binding soluble 3-binding protein(gene name synonym)|uniprotkb:Mac-2-binding protein(gene name synonym)|uniprotkb:Tumor-associated antigen 90K(gene name synonym)|uniprotkb:Basement membrane autoantigen p105(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Cox et al. (2012) pubmed:23667531|imex:IM-28599 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-26574619|imex:IM-28599-5 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_003097.1|dip:DIP-59913N|ensembl:ENSG00000181449(gene)|ensembl:ENST00000325404(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001649"(osteoblast differentiation)|go:"GO:0001654"(eye development)|go:"GO:0001714"(endodermal cell fate specification)|go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006325"(chromatin organization)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0009611"(response to wounding)|go:"GO:0009653"(anatomical structure morphogenesis)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0021781"(glial cell fate commitment)|go:"GO:0021983"(pituitary gland development)|go:"GO:0021984"(adenohypophysis development)|go:"GO:0022409"(positive regulation of cell-cell adhesion)|go:"GO:0030154"(cell differentiation)|go:"GO:0030900"(forebrain development)|go:"GO:0035019"(somatic stem cell population maintenance)|go:"GO:0035198"(miRNA binding)|go:"GO:0042246"(tissue regeneration)|go:"GO:0043281"(regulation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0043410"(positive regulation of MAPK cascade)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045165"(cell fate commitment)|go:"GO:0045597"(positive regulation of cell differentiation)|go:"GO:0045665"(negative regulation of neuron differentiation)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048839"(inner ear development)|go:"GO:0050680"(negative regulation of epithelial cell proliferation)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0070848"(response to growth factor)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:0097150"(neuronal stem cell population maintenance)|interpro:IPR009071(High mobility group box, HMG)|interpro:IPR022097|interpro:IPR032643|interpro:IPR036910|mint:P48431|rcsb pdb:1O4X|rcsb pdb:2LE4|rcsb pdb:6T7B|rcsb pdb:6T90|rcsb pdb:6WX7|rcsb pdb:6WX8|rcsb pdb:6WX9|rcsb pdb:6YOV|reactome:R-HSA-2892245|reactome:R-HSA-2892247|reactome:R-HSA-3769402|reactome:R-HSA-452723|reactome:R-HSA-6785807|reactome:R-HSA-8986944 ensembl:ENSG00000108679(gene)|ensembl:ENST00000262776(transcript)|go:"GO:0005044"(scavenger receptor activity)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0006968"(cellular defense response)|go:"GO:0007165"(signal transduction)|go:"GO:0016020"(membrane)|go:"GO:0031089"(platelet dense granule lumen)|go:"GO:0062023"(collagen-containing extracellular matrix)|go:"GO:0070062"(extracellular exosome)|go:"GO:0072562"(blood microparticle)|interpro:IPR000210(BTB/POZ-like)|interpro:IPR001190(Speract/scavenger receptor)|interpro:IPR011333(BTB/POZ fold)|interpro:IPR011705(BTB/Kelch-associated)|interpro:IPR017448(Speract/scavenger receptor related)|go:"GO:0007155"(cell adhesion)|interpro:IPR036772|mint:Q08380|rcsb pdb:1BY2|rcsb pdb:6GFB|reactome:R-HSA-114608|refseq:NP_005558.1 go:"GO:0005634"(nucleus) - - figure legend:ST2 F2A|comment:proteins identified only in our induced samples in three MudPIT analyses with the more stringent BY-adjusted significance p<0.05|dataset:Brain Disease - Neurological Diseases & Disorders|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-daoy)|taxid:9606(Homo sapiens DAOY cerebellar medulloblastoma cell line) - 2020/12/29 2020/12/29 rogid:cn8gYfKDpQc8J2ygnqny32sIyyU9606 rogid:1LIu+jrlwe2RGkR31frIXz8Ixec9606 rigid:6EMs5+B89Q89RCR/2S2BG6PhH9E false tandem tag:n-n - - - psi-mi:"MI:0658"(multidimensional protein identification technology) psi-mi:"MI:0658"(multidimensional protein identification technology) uniprotkb:P48431 uniprotkb:Q9NVD7 intact:EBI-6124081|uniprotkb:Q14537|ensembl:ENSP00000323588 intact:EBI-747655|uniprotkb:Q96C85|uniprotkb:Q9HA48|ensembl:ENSP00000334008 psi-mi:sox2_human(display_long)|uniprotkb:SOX2(gene name)|psi-mi:SOX2(display_short) psi-mi:parva_human(display_long)|uniprotkb:Calponin-like integrin-linked kinase-binding protein(gene name synonym)|uniprotkb:CH-ILKBP(gene name synonym)|uniprotkb:Matrix-remodeling-associated protein 2(gene name synonym)|uniprotkb:Actopaxin(gene name synonym)|uniprotkb:PARVA(gene name)|psi-mi:PARVA(display_short)|uniprotkb:MXRA2(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Cox et al. (2012) pubmed:23667531|imex:IM-28599 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-26574619|imex:IM-28599-5 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_003097.1|dip:DIP-59913N|ensembl:ENSG00000181449(gene)|ensembl:ENST00000325404(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001649"(osteoblast differentiation)|go:"GO:0001654"(eye development)|go:"GO:0001714"(endodermal cell fate specification)|go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006325"(chromatin organization)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0009611"(response to wounding)|go:"GO:0009653"(anatomical structure morphogenesis)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0021781"(glial cell fate commitment)|go:"GO:0021983"(pituitary gland development)|go:"GO:0021984"(adenohypophysis development)|go:"GO:0022409"(positive regulation of cell-cell adhesion)|go:"GO:0030154"(cell differentiation)|go:"GO:0030900"(forebrain development)|go:"GO:0035019"(somatic stem cell population maintenance)|go:"GO:0035198"(miRNA binding)|go:"GO:0042246"(tissue regeneration)|go:"GO:0043281"(regulation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0043410"(positive regulation of MAPK cascade)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045165"(cell fate commitment)|go:"GO:0045597"(positive regulation of cell differentiation)|go:"GO:0045665"(negative regulation of neuron differentiation)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048839"(inner ear development)|go:"GO:0050680"(negative regulation of epithelial cell proliferation)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0070848"(response to growth factor)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:0097150"(neuronal stem cell population maintenance)|interpro:IPR009071(High mobility group box, HMG)|interpro:IPR022097|interpro:IPR032643|interpro:IPR036910|mint:P48431|rcsb pdb:1O4X|rcsb pdb:2LE4|rcsb pdb:6T7B|rcsb pdb:6T90|rcsb pdb:6WX7|rcsb pdb:6WX8|rcsb pdb:6WX9|rcsb pdb:6YOV|reactome:R-HSA-2892245|reactome:R-HSA-2892247|reactome:R-HSA-3769402|reactome:R-HSA-452723|reactome:R-HSA-6785807|reactome:R-HSA-8986944 refseq:NP_060692.2|ensembl:ENSG00000197702(gene)|ensembl:ENST00000334956(transcript)|go:"GO:0002040"(sprouting angiogenesis)|go:"GO:0003148"(outflow tract septum morphogenesis)|go:"GO:0003779"(actin binding)|go:"GO:0004860"(protein kinase inhibitor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0005925"(focal adhesion)|go:"GO:0007163"(establishment or maintenance of cell polarity)|go:"GO:0008360"(regulation of cell shape)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0030018"(Z disc)|go:"GO:0030027"(lamellipodium)|go:"GO:0030031"(cell projection assembly)|go:"GO:0031532"(actin cytoskeleton reorganization)|go:"GO:0034113"(heterotypic cell-cell adhesion)|go:"GO:0034446"(substrate adhesion-dependent cell spreading)|go:"GO:0045296"(cadherin binding)|go:"GO:0050821"(protein stabilization)|go:"GO:0060271"(cilium assembly)|go:"GO:0070252"(actin-mediated cell contraction)|go:"GO:0071670"(smooth muscle cell chemotaxis)|interpro:IPR001715(Calponin-like actin-binding)|interpro:IPR028433|interpro:IPR036872|mint:Q9NVD7|rcsb pdb:2K2R|rcsb pdb:2VZC|rcsb pdb:2VZD|rcsb pdb:2VZG|rcsb pdb:2VZI|rcsb pdb:3KMU|rcsb pdb:3KMW|rcsb pdb:3REP|reactome:R-HSA-446343|reactome:R-HSA-446353|reactome:R-HSA-446388|go:"GO:0005829"(cytosol)|rcsb pdb:6MIB go:"GO:0005634"(nucleus) - - figure legend:ST2 F2A|comment:proteins identified only in our induced samples in three MudPIT analyses with the more stringent BY-adjusted significance p<0.05|dataset:Brain Disease - Neurological Diseases & Disorders|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-daoy)|taxid:9606(Homo sapiens DAOY cerebellar medulloblastoma cell line) - 2020/12/29 2020/12/29 rogid:cn8gYfKDpQc8J2ygnqny32sIyyU9606 rogid:KjiRqYX7cAl33+lH1FnFGfkaZsM9606 rigid:6EMs5+B89Q89RCR/2S2BG6PhH9E false tandem tag:n-n - - - psi-mi:"MI:0658"(multidimensional protein identification technology) psi-mi:"MI:0658"(multidimensional protein identification technology) uniprotkb:P48431 uniprotkb:Q01813 intact:EBI-6124081|uniprotkb:Q14537|ensembl:ENSP00000323588 intact:EBI-359022|uniprotkb:B3KS15|uniprotkb:Q5VSR7|uniprotkb:Q5VSR8|ensembl:ENSP00000370517 psi-mi:sox2_human(display_long)|uniprotkb:SOX2(gene name)|psi-mi:SOX2(display_short) psi-mi:pfkap_human(display_long)|uniprotkb:PFKP(gene name)|psi-mi:PFKP(display_short)|uniprotkb:PFKF(gene name synonym)|uniprotkb:Phosphohexokinase(gene name synonym)|uniprotkb:Phosphofructo-1-kinase isozyme C(gene name synonym)|uniprotkb:6-phosphofructokinase type C(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Cox et al. (2012) pubmed:23667531|imex:IM-28599 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-26574619|imex:IM-28599-5 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_003097.1|dip:DIP-59913N|ensembl:ENSG00000181449(gene)|ensembl:ENST00000325404(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001649"(osteoblast differentiation)|go:"GO:0001654"(eye development)|go:"GO:0001714"(endodermal cell fate specification)|go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006325"(chromatin organization)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0009611"(response to wounding)|go:"GO:0009653"(anatomical structure morphogenesis)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0021781"(glial cell fate commitment)|go:"GO:0021983"(pituitary gland development)|go:"GO:0021984"(adenohypophysis development)|go:"GO:0022409"(positive regulation of cell-cell adhesion)|go:"GO:0030154"(cell differentiation)|go:"GO:0030900"(forebrain development)|go:"GO:0035019"(somatic stem cell population maintenance)|go:"GO:0035198"(miRNA binding)|go:"GO:0042246"(tissue regeneration)|go:"GO:0043281"(regulation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0043410"(positive regulation of MAPK cascade)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045165"(cell fate commitment)|go:"GO:0045597"(positive regulation of cell differentiation)|go:"GO:0045665"(negative regulation of neuron differentiation)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048839"(inner ear development)|go:"GO:0050680"(negative regulation of epithelial cell proliferation)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0070848"(response to growth factor)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:0097150"(neuronal stem cell population maintenance)|interpro:IPR009071(High mobility group box, HMG)|interpro:IPR022097|interpro:IPR032643|interpro:IPR036910|mint:P48431|rcsb pdb:1O4X|rcsb pdb:2LE4|rcsb pdb:6T7B|rcsb pdb:6T90|rcsb pdb:6WX7|rcsb pdb:6WX8|rcsb pdb:6WX9|rcsb pdb:6YOV|reactome:R-HSA-2892245|reactome:R-HSA-2892247|reactome:R-HSA-3769402|reactome:R-HSA-452723|reactome:R-HSA-6785807|reactome:R-HSA-8986944 refseq:NP_002618.1|ensembl:ENSG00000067057(gene)|ensembl:ENST00000381125(transcript)|go:"GO:0003872"(6-phosphofructokinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005945"(6-phosphofructokinase complex)|go:"GO:0006002"(fructose 6-phosphate metabolic process)|go:"GO:0016020"(membrane)|go:"GO:0016208"(AMP binding)|go:"GO:0030388"(fructose 1,6-bisphosphate metabolic process)|go:"GO:0042802"(identical protein binding)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045296"(cadherin binding)|go:"GO:0046872"(metal ion binding)|go:"GO:0048029"(monosaccharide binding)|go:"GO:0061621"(canonical glycolysis)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070095"(fructose-6-phosphate binding)|go:"GO:1990830"(cellular response to leukemia inhibitory factor)|interpro:IPR000023(Phosphofructokinase)|interpro:IPR009161(6-phosphofructokinase, eukaryotic type)|interpro:IPR015912(Phosphofructokinase, conserved site)|interpro:IPR022953|interpro:IPR035966|interpro:IPR041914|mint:Q01813|rcsb pdb:4RH3|rcsb pdb:4U1R|rcsb pdb:4WL0|rcsb pdb:4XYJ|rcsb pdb:4XYK|rcsb pdb:4XZ2|reactome:R-HSA-70171|refseq:NP_001229268.1|dip:DIP-45850N go:"GO:0005634"(nucleus) - - figure legend:ST2 F2A|comment:proteins identified only in our induced samples in three MudPIT analyses with the more stringent BY-adjusted significance p<0.05|dataset:Brain Disease - Neurological Diseases & Disorders|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-daoy)|taxid:9606(Homo sapiens DAOY cerebellar medulloblastoma cell line) - 2020/12/29 2020/12/29 rogid:cn8gYfKDpQc8J2ygnqny32sIyyU9606 rogid:GNmWbFrQsTMRdVphWG+3DK3wxaA9606 rigid:6EMs5+B89Q89RCR/2S2BG6PhH9E false tandem tag:n-n - - - psi-mi:"MI:0658"(multidimensional protein identification technology) psi-mi:"MI:0658"(multidimensional protein identification technology) uniprotkb:P48431 uniprotkb:P82933 intact:EBI-6124081|uniprotkb:Q14537|ensembl:ENSP00000323588 intact:EBI-721385|intact:EBI-1049991|uniprotkb:Q6PG40|ensembl:ENSP00000258455 psi-mi:sox2_human(display_long)|uniprotkb:SOX2(gene name)|psi-mi:SOX2(display_short) psi-mi:rt09_human(display_long)|uniprotkb:MRPS9(gene name)|psi-mi:MRPS9(display_short)|uniprotkb:RPMS9(gene name synonym)|uniprotkb:Mitochondrial small ribosomal subunit protein uS9m(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Cox et al. (2012) pubmed:23667531|imex:IM-28599 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-26574619|imex:IM-28599-5 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_003097.1|dip:DIP-59913N|ensembl:ENSG00000181449(gene)|ensembl:ENST00000325404(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001649"(osteoblast differentiation)|go:"GO:0001654"(eye development)|go:"GO:0001714"(endodermal cell fate specification)|go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006325"(chromatin organization)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0009611"(response to wounding)|go:"GO:0009653"(anatomical structure morphogenesis)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0021781"(glial cell fate commitment)|go:"GO:0021983"(pituitary gland development)|go:"GO:0021984"(adenohypophysis development)|go:"GO:0022409"(positive regulation of cell-cell adhesion)|go:"GO:0030154"(cell differentiation)|go:"GO:0030900"(forebrain development)|go:"GO:0035019"(somatic stem cell population maintenance)|go:"GO:0035198"(miRNA binding)|go:"GO:0042246"(tissue regeneration)|go:"GO:0043281"(regulation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0043410"(positive regulation of MAPK cascade)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045165"(cell fate commitment)|go:"GO:0045597"(positive regulation of cell differentiation)|go:"GO:0045665"(negative regulation of neuron differentiation)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048839"(inner ear development)|go:"GO:0050680"(negative regulation of epithelial cell proliferation)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0070848"(response to growth factor)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:0097150"(neuronal stem cell population maintenance)|interpro:IPR009071(High mobility group box, HMG)|interpro:IPR022097|interpro:IPR032643|interpro:IPR036910|mint:P48431|rcsb pdb:1O4X|rcsb pdb:2LE4|rcsb pdb:6T7B|rcsb pdb:6T90|rcsb pdb:6WX7|rcsb pdb:6WX8|rcsb pdb:6WX9|rcsb pdb:6YOV|reactome:R-HSA-2892245|reactome:R-HSA-2892247|reactome:R-HSA-3769402|reactome:R-HSA-452723|reactome:R-HSA-6785807|reactome:R-HSA-8986944 refseq:NP_872578.1|ensembl:ENSG00000135972(gene)|ensembl:ENST00000258455(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005730"(nucleolus)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005763"(mitochondrial small ribosomal subunit)|go:"GO:0006412"(translation)|go:"GO:0015935"(small ribosomal subunit)|go:"GO:0042769"(obsolete DNA damage response, detection of DNA damage)|interpro:IPR000754(Ribosomal protein S9)|interpro:IPR014721(Ribosomal protein S5 domain 2-type fold)|interpro:IPR020568|interpro:IPR020574|mint:P82933|rcsb pdb:3J9M|rcsb pdb:6NU2|rcsb pdb:6NU3|rcsb pdb:6RW4|rcsb pdb:6RW5|rcsb pdb:6VLZ|rcsb pdb:6VMI|rcsb pdb:6ZM5|rcsb pdb:6ZM6|rcsb pdb:6ZS9|rcsb pdb:6ZSA|rcsb pdb:6ZSB|rcsb pdb:6ZSC|rcsb pdb:6ZSD|rcsb pdb:6ZSG|rcsb pdb:7A5F|rcsb pdb:7A5G|rcsb pdb:7A5I|rcsb pdb:7A5K|rcsb pdb:7L08|rcsb pdb:7OG4|reactome:R-HSA-5368286|reactome:R-HSA-5389840|reactome:R-HSA-5419276|rcsb pdb:6ZSE go:"GO:0005634"(nucleus) - - figure legend:ST2 F2A|comment:proteins identified only in our induced samples in three MudPIT analyses with the more stringent BY-adjusted significance p<0.05|dataset:Brain Disease - Neurological Diseases & Disorders|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-daoy)|taxid:9606(Homo sapiens DAOY cerebellar medulloblastoma cell line) - 2020/12/29 2020/12/29 rogid:cn8gYfKDpQc8J2ygnqny32sIyyU9606 rogid:XNB4GL84eYgYFEB3WxOtoD3Ub989606 rigid:6EMs5+B89Q89RCR/2S2BG6PhH9E false tandem tag:n-n - - - psi-mi:"MI:0658"(multidimensional protein identification technology) psi-mi:"MI:0658"(multidimensional protein identification technology) uniprotkb:P48431 uniprotkb:Q9UBB5 intact:EBI-6124081|uniprotkb:Q14537|ensembl:ENSP00000323588 intact:EBI-923391|uniprotkb:Q9UIS8|uniprotkb:O95242|ensembl:ENSP00000256429 psi-mi:sox2_human(display_long)|uniprotkb:SOX2(gene name)|psi-mi:SOX2(display_short) psi-mi:mbd2_human(display_long)|uniprotkb:MBD2(gene name)|psi-mi:MBD2(display_short)|uniprotkb:Methyl-CpG-binding protein MBD2(gene name synonym)|uniprotkb:Demethylase(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Cox et al. (2012) pubmed:23667531|imex:IM-28599 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-26574619|imex:IM-28599-5 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_003097.1|dip:DIP-59913N|ensembl:ENSG00000181449(gene)|ensembl:ENST00000325404(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001649"(osteoblast differentiation)|go:"GO:0001654"(eye development)|go:"GO:0001714"(endodermal cell fate specification)|go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006325"(chromatin organization)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0009611"(response to wounding)|go:"GO:0009653"(anatomical structure morphogenesis)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0021781"(glial cell fate commitment)|go:"GO:0021983"(pituitary gland development)|go:"GO:0021984"(adenohypophysis development)|go:"GO:0022409"(positive regulation of cell-cell adhesion)|go:"GO:0030154"(cell differentiation)|go:"GO:0030900"(forebrain development)|go:"GO:0035019"(somatic stem cell population maintenance)|go:"GO:0035198"(miRNA binding)|go:"GO:0042246"(tissue regeneration)|go:"GO:0043281"(regulation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0043410"(positive regulation of MAPK cascade)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045165"(cell fate commitment)|go:"GO:0045597"(positive regulation of cell differentiation)|go:"GO:0045665"(negative regulation of neuron differentiation)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048839"(inner ear development)|go:"GO:0050680"(negative regulation of epithelial cell proliferation)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0070848"(response to growth factor)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:0097150"(neuronal stem cell population maintenance)|interpro:IPR009071(High mobility group box, HMG)|interpro:IPR022097|interpro:IPR032643|interpro:IPR036910|mint:P48431|rcsb pdb:1O4X|rcsb pdb:2LE4|rcsb pdb:6T7B|rcsb pdb:6T90|rcsb pdb:6WX7|rcsb pdb:6WX8|rcsb pdb:6WX9|rcsb pdb:6YOV|reactome:R-HSA-2892245|reactome:R-HSA-2892247|reactome:R-HSA-3769402|reactome:R-HSA-452723|reactome:R-HSA-6785807|reactome:R-HSA-8986944 refseq:NP_003918.1|refseq:NP_056647.1|ensembl:ENSG00000134046(gene)|ensembl:ENST00000256429(transcript)|go:"GO:0000118"(histone deacetylase complex)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000792"(heterochromatin)|go:"GO:0003682"(chromatin binding)|go:"GO:0003696"(satellite DNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006346"(DNA methylation-dependent heterochromatin assembly)|go:"GO:0007507"(heart development)|go:"GO:0007568"(aging)|go:"GO:0008327"(methyl-CpG binding)|go:"GO:0009612"(response to mechanical stimulus)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030177"(positive regulation of Wnt signaling pathway)|go:"GO:0031667"(response to nutrient levels)|go:"GO:0032355"(response to estradiol)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034622"|go:"GO:0035197"(siRNA binding)|go:"GO:0035563"(positive regulation of chromatin binding)|go:"GO:0042127"(regulation of cell population proliferation)|go:"GO:0042711"(maternal behavior)|go:"GO:0043044"|go:"GO:0044030"(regulation of DNA methylation)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0048568"(embryonic organ development)|go:"GO:0070742"(C2H2 zinc finger domain binding)|go:"GO:0071407"(cellular response to organic cyclic compound)|interpro:IPR001739(Methyl-CpG DNA binding)|interpro:IPR016177(DNA-binding, integrase-type)|interpro:IPR025884|interpro:IPR032343|mint:Q9UBB5|rcsb pdb:2L2L|rcsb pdb:6C1A|rcsb pdb:6C1T|rcsb pdb:6C1U|rcsb pdb:6C1V|rcsb pdb:6C2F|rcsb pdb:6CNP|rcsb pdb:6CNQ|rcsb pdb:7AO8|rcsb pdb:7AO9|rcsb pdb:7AOA|reactome:R-HSA-427413|reactome:R-HSA-73728 go:"GO:0005634"(nucleus) - - figure legend:ST2 F2A|comment:proteins identified only in our induced samples in three MudPIT analyses with the more stringent BY-adjusted significance p<0.05|dataset:Brain Disease - Neurological Diseases & Disorders|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-daoy)|taxid:9606(Homo sapiens DAOY cerebellar medulloblastoma cell line) - 2020/12/29 2020/12/29 rogid:cn8gYfKDpQc8J2ygnqny32sIyyU9606 rogid:8DO+M6oIpbSfTFPVLADdXaaqzEU9606 rigid:6EMs5+B89Q89RCR/2S2BG6PhH9E false tandem tag:n-n - - - psi-mi:"MI:0658"(multidimensional protein identification technology) psi-mi:"MI:0658"(multidimensional protein identification technology) uniprotkb:P48431 uniprotkb:O00429 intact:EBI-6124081|uniprotkb:Q14537|ensembl:ENSP00000323588 intact:EBI-724571|uniprotkb:O14541|uniprotkb:O60709|uniprotkb:Q7L6B3|uniprotkb:Q8TBT7|uniprotkb:Q9BWM1|uniprotkb:Q9Y5J2|uniprotkb:B4DSU8|uniprotkb:A8K4X9|ensembl:ENSP00000450399|uniprotkb:B4DGC9|uniprotkb:J3KPI2|uniprotkb:Q59GN9|uniprotkb:G8JLD5 psi-mi:sox2_human(display_long)|uniprotkb:SOX2(gene name)|psi-mi:SOX2(display_short) psi-mi:dnm1l_human(display_long)|uniprotkb:Dynamin-like protein(gene name synonym)|uniprotkb:Dnm1p/Vps1p-like protein(gene name synonym)|uniprotkb:Dynamin family member proline-rich carboxyl-terminal domain less(gene name synonym)|uniprotkb:Dynamin-related protein 1(gene name synonym)|uniprotkb:Dynamin-like protein 4(gene name synonym)|uniprotkb:Dynamin-like protein IV(gene name synonym)|uniprotkb:DNM1L(gene name)|psi-mi:DNM1L(display_short)|uniprotkb:DLP1(gene name synonym)|uniprotkb:DRP1(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Cox et al. (2012) pubmed:23667531|imex:IM-28599 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-26574619|imex:IM-28599-5 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_003097.1|dip:DIP-59913N|ensembl:ENSG00000181449(gene)|ensembl:ENST00000325404(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001649"(osteoblast differentiation)|go:"GO:0001654"(eye development)|go:"GO:0001714"(endodermal cell fate specification)|go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006325"(chromatin organization)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0009611"(response to wounding)|go:"GO:0009653"(anatomical structure morphogenesis)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0021781"(glial cell fate commitment)|go:"GO:0021983"(pituitary gland development)|go:"GO:0021984"(adenohypophysis development)|go:"GO:0022409"(positive regulation of cell-cell adhesion)|go:"GO:0030154"(cell differentiation)|go:"GO:0030900"(forebrain development)|go:"GO:0035019"(somatic stem cell population maintenance)|go:"GO:0035198"(miRNA binding)|go:"GO:0042246"(tissue regeneration)|go:"GO:0043281"(regulation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0043410"(positive regulation of MAPK cascade)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045165"(cell fate commitment)|go:"GO:0045597"(positive regulation of cell differentiation)|go:"GO:0045665"(negative regulation of neuron differentiation)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048839"(inner ear development)|go:"GO:0050680"(negative regulation of epithelial cell proliferation)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0070848"(response to growth factor)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:0097150"(neuronal stem cell population maintenance)|interpro:IPR009071(High mobility group box, HMG)|interpro:IPR022097|interpro:IPR032643|interpro:IPR036910|mint:P48431|rcsb pdb:1O4X|rcsb pdb:2LE4|rcsb pdb:6T7B|rcsb pdb:6T90|rcsb pdb:6WX7|rcsb pdb:6WX8|rcsb pdb:6WX9|rcsb pdb:6YOV|reactome:R-HSA-2892245|reactome:R-HSA-2892247|reactome:R-HSA-3769402|reactome:R-HSA-452723|reactome:R-HSA-6785807|reactome:R-HSA-8986944 refseq:NP_005681.2|refseq:NP_036192.2|refseq:NP_036193.2|ensembl:ENSG00000087470(gene)|ensembl:ENST00000549701(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0000266"(mitochondrial fission)|go:"GO:0001836"(release of cytochrome c from mitochondria)|go:"GO:0003374"(dynamin family protein polymerization involved in mitochondrial fission)|go:"GO:0003924"(GTPase activity)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005777"(peroxisome)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0005874"(microtubule)|go:"GO:0005903"(brush border)|go:"GO:0005905"(clathrin-coated pit)|go:"GO:0006816"(calcium ion transport)|go:"GO:0007005"(mitochondrion organization)|go:"GO:0008017"(microtubule binding)|go:"GO:0008289"(lipid binding)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0010637"(negative regulation of mitochondrial fusion)|go:"GO:0010821"(regulation of mitochondrion organization)|go:"GO:0016020"(membrane)|go:"GO:0016559"(peroxisome fission)|go:"GO:0030276"(clathrin binding)|go:"GO:0030672"(synaptic vesicle membrane)|go:"GO:0030742"(GTP-dependent protein binding)|go:"GO:0031267"(small GTPase binding)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0031966"(mitochondrial membrane)|go:"GO:0032991"(protein-containing complex)|go:"GO:0036466"(synaptic vesicle recycling via endosome)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0043653"(mitochondrial fragmentation involved in apoptotic process)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0048312"(intracellular distribution of mitochondria)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0048488"(synaptic vesicle endocytosis)|go:"GO:0048511"(rhythmic process)|go:"GO:0050714"(positive regulation of protein secretion)|go:"GO:0051259"(protein complex oligomerization)|go:"GO:0051433"(BH2 domain binding)|go:"GO:0060047"(heart contraction)|go:"GO:0061003"(positive regulation of dendritic spine morphogenesis)|go:"GO:0061025"(membrane fusion)|go:"GO:0065003"(protein-containing complex assembly)|go:"GO:0070266"(necroptotic process)|go:"GO:0070584"(mitochondrion morphogenesis)|go:"GO:0070585"(protein localization to mitochondrion)|go:"GO:0090023"(positive regulation of neutrophil chemotaxis)|go:"GO:0090141"(positive regulation of mitochondrial fission)|go:"GO:0090149"(mitochondrial membrane fission)|go:"GO:0090200"(positive regulation of release of cytochrome c from mitochondria)|go:"GO:0090650"(cellular response to oxygen-glucose deprivation)|go:"GO:1900244"(positive regulation of synaptic vesicle endocytosis)|go:"GO:1903146"(regulation of autophagy of mitochondrion)|go:"GO:1903578"(regulation of ATP metabolic process)|go:"GO:1904579"(cellular response to thapsigargin)|go:"GO:1904666"(regulation of ubiquitin protein ligase activity)|go:"GO:1905395"(response to flavonoid)|go:"GO:1990910"(response to hypobaric hypoxia)|go:"GO:2000302"(positive regulation of synaptic vesicle exocytosis)|go:"GO:2001244"(positive regulation of intrinsic apoptotic signaling pathway)|interpro:IPR000375(Dynamin central region)|interpro:IPR001401(Dynamin, GTPase region)|interpro:IPR003130(Dynamin GTPase effector)|interpro:IPR019762|interpro:IPR020850|interpro:IPR022812|interpro:IPR027417|interpro:IPR030381|interpro:IPR030556|mint:O00429|rcsb pdb:3W6N|rcsb pdb:3W6O|rcsb pdb:3W6P|rcsb pdb:4BEJ|rcsb pdb:4H1U|rcsb pdb:4H1V|rcsb pdb:5WP9|go:"GO:0098835"(presynaptic endocytic zone membrane)|go:"GO:1900063"(regulation of peroxisome organization)|reactome:R-HSA-75153|refseq:NP_001265392.1|refseq:NP_001265393.1|refseq:NP_001265394.1|refseq:NP_001265395.1|refseq:NP_001317309.1|dip:DIP-42704N go:"GO:0005634"(nucleus) - crc64:F9521A376B785B71 figure legend:ST2 F2A|comment:proteins identified only in our induced samples in three MudPIT analyses with the more stringent BY-adjusted significance p<0.05|dataset:Brain Disease - Neurological Diseases & Disorders|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-daoy)|taxid:9606(Homo sapiens DAOY cerebellar medulloblastoma cell line) - 2020/12/29 2020/12/29 rogid:cn8gYfKDpQc8J2ygnqny32sIyyU9606 rogid:hmh7m80FPMdx6/3eUY6l0IK/AqY9606 rigid:6EMs5+B89Q89RCR/2S2BG6PhH9E false tandem tag:n-n - - - psi-mi:"MI:0658"(multidimensional protein identification technology) psi-mi:"MI:0658"(multidimensional protein identification technology) uniprotkb:P48431 uniprotkb:P82650 intact:EBI-6124081|uniprotkb:Q14537|ensembl:ENSP00000323588 intact:EBI-1050752|ensembl:ENSP00000418008|ensembl:ENSP00000505414|uniprotkb:Q9H3I1 psi-mi:sox2_human(display_long)|uniprotkb:SOX2(gene name)|psi-mi:SOX2(display_short) psi-mi:rt22_human(display_long)|uniprotkb:MRPS22(gene name)|psi-mi:MRPS22(display_short)|uniprotkb:C3orf5(gene name synonym)|uniprotkb:RPMS22(gene name synonym)|uniprotkb:GK002(orf name)|uniprotkb:Mitochondrial small ribosomal subunit protein mS22(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Cox et al. (2012) pubmed:23667531|imex:IM-28599 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-26574619|imex:IM-28599-5 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_003097.1|dip:DIP-59913N|ensembl:ENSG00000181449(gene)|ensembl:ENST00000325404(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001649"(osteoblast differentiation)|go:"GO:0001654"(eye development)|go:"GO:0001714"(endodermal cell fate specification)|go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006325"(chromatin organization)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0009611"(response to wounding)|go:"GO:0009653"(anatomical structure morphogenesis)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0021781"(glial cell fate commitment)|go:"GO:0021983"(pituitary gland development)|go:"GO:0021984"(adenohypophysis development)|go:"GO:0022409"(positive regulation of cell-cell adhesion)|go:"GO:0030154"(cell differentiation)|go:"GO:0030900"(forebrain development)|go:"GO:0035019"(somatic stem cell population maintenance)|go:"GO:0035198"(miRNA binding)|go:"GO:0042246"(tissue regeneration)|go:"GO:0043281"(regulation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0043410"(positive regulation of MAPK cascade)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045165"(cell fate commitment)|go:"GO:0045597"(positive regulation of cell differentiation)|go:"GO:0045665"(negative regulation of neuron differentiation)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048839"(inner ear development)|go:"GO:0050680"(negative regulation of epithelial cell proliferation)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0070848"(response to growth factor)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:0097150"(neuronal stem cell population maintenance)|interpro:IPR009071(High mobility group box, HMG)|interpro:IPR022097|interpro:IPR032643|interpro:IPR036910|mint:P48431|rcsb pdb:1O4X|rcsb pdb:2LE4|rcsb pdb:6T7B|rcsb pdb:6T90|rcsb pdb:6WX7|rcsb pdb:6WX8|rcsb pdb:6WX9|rcsb pdb:6YOV|reactome:R-HSA-2892245|reactome:R-HSA-2892247|reactome:R-HSA-3769402|reactome:R-HSA-452723|reactome:R-HSA-6785807|reactome:R-HSA-8986944 refseq:NP_064576.1|ensembl:ENSG00000175110(gene)|ensembl:ENST00000495075(transcript)|ensembl:ENST00000680020(transcript)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005761"(mitochondrial ribosome)|go:"GO:0005763"(mitochondrial small ribosomal subunit)|interpro:IPR019374|mint:P82650|rcsb pdb:3J9M|rcsb pdb:6NU2|rcsb pdb:6NU3|rcsb pdb:6RW4|rcsb pdb:6RW5|rcsb pdb:6VLZ|rcsb pdb:6VMI|rcsb pdb:6ZM5|rcsb pdb:6ZM6|rcsb pdb:6ZS9|rcsb pdb:6ZSA|rcsb pdb:6ZSB|rcsb pdb:6ZSC|rcsb pdb:6ZSD|rcsb pdb:6ZSE|rcsb pdb:6ZSG|rcsb pdb:7A5F|rcsb pdb:7A5G|rcsb pdb:7A5I|rcsb pdb:7A5K|rcsb pdb:7L08|rcsb pdb:7OG4|reactome:R-HSA-5368286|reactome:R-HSA-5389840|reactome:R-HSA-5419276 go:"GO:0005634"(nucleus) - - figure legend:ST2 F2A|comment:proteins identified only in our induced samples in three MudPIT analyses with the more stringent BY-adjusted significance p<0.05|dataset:Brain Disease - Neurological Diseases & Disorders|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-daoy)|taxid:9606(Homo sapiens DAOY cerebellar medulloblastoma cell line) - 2020/12/29 2020/12/29 rogid:cn8gYfKDpQc8J2ygnqny32sIyyU9606 rogid:T0htF4/rvOZUZ3RcuCjWvEg9iTE9606 rigid:6EMs5+B89Q89RCR/2S2BG6PhH9E false tandem tag:n-n - - - psi-mi:"MI:0658"(multidimensional protein identification technology) psi-mi:"MI:0658"(multidimensional protein identification technology) uniprotkb:P48431 uniprotkb:O15379 intact:EBI-6124081|uniprotkb:Q14537|ensembl:ENSP00000323588 intact:EBI-607682|uniprotkb:O43268|uniprotkb:Q9UEI5|uniprotkb:Q9UEV0|uniprotkb:D3DQE1|ensembl:ENSP00000302967 psi-mi:sox2_human(display_long)|uniprotkb:SOX2(gene name)|psi-mi:SOX2(display_short) psi-mi:hdac3_human(display_long)|uniprotkb:HDAC3(gene name)|psi-mi:HDAC3(display_short)|uniprotkb:RPD3-2(gene name synonym)|uniprotkb:SMAP45(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Cox et al. (2012) pubmed:23667531|imex:IM-28599 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-26574619|imex:IM-28599-5 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_003097.1|dip:DIP-59913N|ensembl:ENSG00000181449(gene)|ensembl:ENST00000325404(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001649"(osteoblast differentiation)|go:"GO:0001654"(eye development)|go:"GO:0001714"(endodermal cell fate specification)|go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006325"(chromatin organization)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0009611"(response to wounding)|go:"GO:0009653"(anatomical structure morphogenesis)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0021781"(glial cell fate commitment)|go:"GO:0021983"(pituitary gland development)|go:"GO:0021984"(adenohypophysis development)|go:"GO:0022409"(positive regulation of cell-cell adhesion)|go:"GO:0030154"(cell differentiation)|go:"GO:0030900"(forebrain development)|go:"GO:0035019"(somatic stem cell population maintenance)|go:"GO:0035198"(miRNA binding)|go:"GO:0042246"(tissue regeneration)|go:"GO:0043281"(regulation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0043410"(positive regulation of MAPK cascade)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045165"(cell fate commitment)|go:"GO:0045597"(positive regulation of cell differentiation)|go:"GO:0045665"(negative regulation of neuron differentiation)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048839"(inner ear development)|go:"GO:0050680"(negative regulation of epithelial cell proliferation)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0070848"(response to growth factor)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:0097150"(neuronal stem cell population maintenance)|interpro:IPR009071(High mobility group box, HMG)|interpro:IPR022097|interpro:IPR032643|interpro:IPR036910|mint:P48431|rcsb pdb:1O4X|rcsb pdb:2LE4|rcsb pdb:6T7B|rcsb pdb:6T90|rcsb pdb:6WX7|rcsb pdb:6WX8|rcsb pdb:6WX9|rcsb pdb:6YOV|reactome:R-HSA-2892245|reactome:R-HSA-2892247|reactome:R-HSA-3769402|reactome:R-HSA-452723|reactome:R-HSA-6785807|reactome:R-HSA-8986944 refseq:NP_003874.2|dip:DIP-24253N|ensembl:ENSG00000171720(gene)|ensembl:ENST00000305264(transcript)|go:"GO:0000118"(histone deacetylase complex)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0001222"(transcription corepressor binding)|go:"GO:0001934"(positive regulation of protein phosphorylation)|go:"GO:0003682"(chromatin binding)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0004407"(histone deacetylase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006325"(chromatin organization)|go:"GO:0006476"(protein deacetylation)|go:"GO:0008134"(transcription factor binding)|go:"GO:0017053"(transcription repressor complex)|go:"GO:0019899"(enzyme binding)|go:"GO:0030332"(cyclin binding)|go:"GO:0031398"(positive regulation of protein ubiquitination)|go:"GO:0031647"(regulation of protein stability)|go:"GO:0032008"(positive regulation of TOR signaling)|go:"GO:0032041"("NAD-dependent histone deacetylase activity (H3-K14 specific)")|go:"GO:0032922"(circadian regulation of gene expression)|go:"GO:0033558"(protein deacetylase activity)|go:"GO:0042307"(positive regulation of protein import into nucleus)|go:"GO:0042752"(regulation of circadian rhythm)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046329"(negative regulation of JNK cascade)|go:"GO:0051059"(NF-kappaB binding)|go:"GO:0051225"(spindle assembly)|go:"GO:0070932"(histone H3 deacetylation)|go:"GO:0070933"(histone H4 deacetylation)|go:"GO:0071498"(cellular response to fluid shear stress)|go:"GO:0072686"(mitotic spindle)|go:"GO:0120162"(positive regulation of cold-induced thermogenesis)|go:"GO:0140297"(DNA-binding transcription factor binding)|interpro:IPR000286(Histone deacetylase superfamily)|interpro:IPR003084(Histone deacetylase)|interpro:IPR023696|interpro:IPR023801|interpro:IPR037138|mint:O15379|rcsb pdb:4A69|reactome:R-HSA-1368071|reactome:R-HSA-193670|reactome:R-HSA-1989781|reactome:R-HSA-2122947|reactome:R-HSA-2151201|reactome:R-HSA-2644606|reactome:R-HSA-2894862|reactome:R-HSA-3214815|reactome:R-HSA-350054|reactome:R-HSA-381340|reactome:R-HSA-390471|reactome:R-HSA-400206|reactome:R-HSA-5617472|reactome:R-HSA-8940973|reactome:R-HSA-8943724|reactome:R-HSA-9022537|reactome:R-HSA-9022692|reactome:R-HSA-9029569|reactome:R-HSA-9609690|reactome:R-HSA-9707564|reactome:R-HSA-9707616|reactome:R-HSA-400253 go:"GO:0005634"(nucleus) - - figure legend:ST2 F2A|comment:proteins identified only in our induced samples in three MudPIT analyses with the more stringent BY-adjusted significance p<0.05|dataset:Brain Disease - Neurological Diseases & Disorders|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-daoy)|taxid:9606(Homo sapiens DAOY cerebellar medulloblastoma cell line) - 2020/12/29 2020/12/29 rogid:cn8gYfKDpQc8J2ygnqny32sIyyU9606 rogid:X5pnE98s15eXKev3nauN7ri5kqg9606 rigid:6EMs5+B89Q89RCR/2S2BG6PhH9E false tandem tag:n-n - - - psi-mi:"MI:0658"(multidimensional protein identification technology) psi-mi:"MI:0658"(multidimensional protein identification technology) uniprotkb:P48431 uniprotkb:P23258 intact:EBI-6124081|uniprotkb:Q14537|ensembl:ENSP00000323588 intact:EBI-302589|ensembl:ENSP00000251413|uniprotkb:Q9BW59|uniprotkb:Q53X79 psi-mi:sox2_human(display_long)|uniprotkb:SOX2(gene name)|psi-mi:SOX2(display_short) psi-mi:tbg1_human(display_long)|uniprotkb:TUBG1(gene name)|psi-mi:TUBG1(display_short)|uniprotkb:TUBG(gene name synonym)|uniprotkb:Gamma-1-tubulin(gene name synonym)|uniprotkb:Gamma-tubulin complex component 1(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Cox et al. (2012) pubmed:23667531|imex:IM-28599 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-26574619|imex:IM-28599-5 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_003097.1|dip:DIP-59913N|ensembl:ENSG00000181449(gene)|ensembl:ENST00000325404(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001649"(osteoblast differentiation)|go:"GO:0001654"(eye development)|go:"GO:0001714"(endodermal cell fate specification)|go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006325"(chromatin organization)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0009611"(response to wounding)|go:"GO:0009653"(anatomical structure morphogenesis)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0021781"(glial cell fate commitment)|go:"GO:0021983"(pituitary gland development)|go:"GO:0021984"(adenohypophysis development)|go:"GO:0022409"(positive regulation of cell-cell adhesion)|go:"GO:0030154"(cell differentiation)|go:"GO:0030900"(forebrain development)|go:"GO:0035019"(somatic stem cell population maintenance)|go:"GO:0035198"(miRNA binding)|go:"GO:0042246"(tissue regeneration)|go:"GO:0043281"(regulation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0043410"(positive regulation of MAPK cascade)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045165"(cell fate commitment)|go:"GO:0045597"(positive regulation of cell differentiation)|go:"GO:0045665"(negative regulation of neuron differentiation)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048839"(inner ear development)|go:"GO:0050680"(negative regulation of epithelial cell proliferation)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0070848"(response to growth factor)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:0097150"(neuronal stem cell population maintenance)|interpro:IPR009071(High mobility group box, HMG)|interpro:IPR022097|interpro:IPR032643|interpro:IPR036910|mint:P48431|rcsb pdb:1O4X|rcsb pdb:2LE4|rcsb pdb:6T7B|rcsb pdb:6T90|rcsb pdb:6WX7|rcsb pdb:6WX8|rcsb pdb:6WX9|rcsb pdb:6YOV|reactome:R-HSA-2892245|reactome:R-HSA-2892247|reactome:R-HSA-3769402|reactome:R-HSA-452723|reactome:R-HSA-6785807|reactome:R-HSA-8986944 interpro:IPR018316|interpro:IPR023123|interpro:IPR036525|interpro:IPR037103|mint:P23258|rcsb pdb:1Z5V|rcsb pdb:1Z5W|rcsb pdb:3CB2|rcsb pdb:6V5V|rcsb pdb:6V6S|rcsb pdb:7AS4|reactome:R-HSA-2565942|reactome:R-HSA-380259|reactome:R-HSA-380270|reactome:R-HSA-380284|reactome:R-HSA-380320|interpro:IPR017975|reactome:R-HSA-5620912|reactome:R-HSA-8854518|ensembl:ENSG00000131462(gene)|ensembl:ENST00000251413(transcript)|go:"GO:0000070"(mitotic sister chromatid segregation)|go:"GO:0000212"(meiotic spindle organization)|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0000242"(pericentriolar material)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0000794"(condensed nuclear chromosome)|go:"GO:0000930"(gamma-tubulin complex)|go:"GO:0005200"(structural constituent of cytoskeleton)|go:"GO:0005525"(GTP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005819"(spindle)|go:"GO:0005827"(polar microtubule)|go:"GO:0005829"(cytosol)|go:"GO:0005874"(microtubule)|go:"GO:0005881"(cytoplasmic microtubule)|go:"GO:0007020"(microtubule nucleation)|go:"GO:0007052"(mitotic spindle organization)|go:"GO:0031122"(cytoplasmic microtubule organization)|go:"GO:0031252"(cell leading edge)|go:"GO:0036064"(ciliary basal body)|go:"GO:0042802"(identical protein binding)|go:"GO:0045177"(apical part of cell)|go:"GO:0055037"(recycling endosome)|go:"GO:0097730"(non-motile cilium)|go:"GO:1990498"(mitotic spindle microtubule)|interpro:IPR000217(Tubulin)|interpro:IPR002454(Gamma tubulin)|go:"GO:0005814"(centriole)|interpro:IPR003008(Tubulin/FtsZ, GTPase)|interpro:IPR008280(Tubulin/FtsZ, C-terminal)|refseq:NP_001061.2|dip:DIP-29890N go:"GO:0005634"(nucleus) - - figure legend:ST2 F2A|comment:proteins identified only in our induced samples in three MudPIT analyses with the more stringent BY-adjusted significance p<0.05|dataset:Brain Disease - Neurological Diseases & Disorders|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-daoy)|taxid:9606(Homo sapiens DAOY cerebellar medulloblastoma cell line) - 2020/12/29 2020/12/29 rogid:cn8gYfKDpQc8J2ygnqny32sIyyU9606 rogid:Y5WLH1ZKlS7FOa9ePmH3dpdE8Xk9606 rigid:6EMs5+B89Q89RCR/2S2BG6PhH9E false tandem tag:n-n - - - psi-mi:"MI:0658"(multidimensional protein identification technology) psi-mi:"MI:0658"(multidimensional protein identification technology) uniprotkb:P48431 uniprotkb:Q99081 intact:EBI-6124081|uniprotkb:Q14537|ensembl:ENSP00000323588 intact:EBI-722877|uniprotkb:Q86VM2|ensembl:ENSP00000267811|ensembl:ENSP00000453737|uniprotkb:Q7Z3D9|uniprotkb:Q86TC1|uniprotkb:B4E1W1 psi-mi:sox2_human(display_long)|uniprotkb:SOX2(gene name)|psi-mi:SOX2(display_short) psi-mi:htf4_human(display_long)|uniprotkb:Transcription factor HTF-4(gene name synonym)|uniprotkb:E-box-binding protein(gene name synonym)|uniprotkb:DNA-binding protein HTF4(gene name synonym)|uniprotkb:TCF12(gene name)|psi-mi:TCF12(display_short)|uniprotkb:HEB(gene name synonym)|uniprotkb:HTF4(gene name synonym)|uniprotkb:BHLHB20(gene name synonym)|uniprotkb:Class B basic helix-loop-helix protein 20(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Cox et al. (2012) pubmed:23667531|imex:IM-28599 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-26574619|imex:IM-28599-5 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_003097.1|dip:DIP-59913N|ensembl:ENSG00000181449(gene)|ensembl:ENST00000325404(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001649"(osteoblast differentiation)|go:"GO:0001654"(eye development)|go:"GO:0001714"(endodermal cell fate specification)|go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006325"(chromatin organization)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0009611"(response to wounding)|go:"GO:0009653"(anatomical structure morphogenesis)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0021781"(glial cell fate commitment)|go:"GO:0021983"(pituitary gland development)|go:"GO:0021984"(adenohypophysis development)|go:"GO:0022409"(positive regulation of cell-cell adhesion)|go:"GO:0030154"(cell differentiation)|go:"GO:0030900"(forebrain development)|go:"GO:0035019"(somatic stem cell population maintenance)|go:"GO:0035198"(miRNA binding)|go:"GO:0042246"(tissue regeneration)|go:"GO:0043281"(regulation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0043410"(positive regulation of MAPK cascade)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045165"(cell fate commitment)|go:"GO:0045597"(positive regulation of cell differentiation)|go:"GO:0045665"(negative regulation of neuron differentiation)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048839"(inner ear development)|go:"GO:0050680"(negative regulation of epithelial cell proliferation)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0070848"(response to growth factor)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:0097150"(neuronal stem cell population maintenance)|interpro:IPR009071(High mobility group box, HMG)|interpro:IPR022097|interpro:IPR032643|interpro:IPR036910|mint:P48431|rcsb pdb:1O4X|rcsb pdb:2LE4|rcsb pdb:6T7B|rcsb pdb:6T90|rcsb pdb:6WX7|rcsb pdb:6WX8|rcsb pdb:6WX9|rcsb pdb:6YOV|reactome:R-HSA-2892245|reactome:R-HSA-2892247|reactome:R-HSA-3769402|reactome:R-HSA-452723|reactome:R-HSA-6785807|reactome:R-HSA-8986944 refseq:NP_001309086.1|refseq:NP_003196.1|refseq:NP_996919.1|refseq:NP_996920.1|refseq:NP_996921.1|refseq:NP_996923.1|ensembl:ENSG00000140262(gene)|ensembl:ENST00000267811(transcript)|ensembl:ENST00000557843(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0000987"(cis-regulatory region sequence-specific DNA binding)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006955"(immune response)|go:"GO:0007399"(nervous system development)|go:"GO:0007517"(muscle organ development)|go:"GO:0008134"(transcription factor binding)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0016607"(nuclear speck)|go:"GO:0030154"(cell differentiation)|go:"GO:0035497"(cAMP response element binding)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0043425"(bHLH transcription factor binding)|go:"GO:0045666"(positive regulation of neuron differentiation)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046332"(SMAD binding)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0070888"(E-box binding)|go:"GO:0071837"(HMG box domain binding)|go:"GO:0090575"(RNA polymerase II transcription regulator complex)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR011598(Helix-loop-helix DNA-binding)|interpro:IPR036638|refseq:NP_001309080.1|refseq:NP_001293149.1|refseq:NP_001309088.1|refseq:NP_001309091.1|refseq:NP_001309094.1|dip:DIP-29403N|mint:Q99081|rcsb pdb:2KNH|rcsb pdb:4JOL|reactome:R-HSA-525793|reactome:R-HSA-8939236|reactome:R-HSA-9031628 go:"GO:0005634"(nucleus) - - figure legend:ST2 F2A|comment:proteins identified only in our induced samples in three MudPIT analyses with the more stringent BY-adjusted significance p<0.05|dataset:Brain Disease - Neurological Diseases & Disorders|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-daoy)|taxid:9606(Homo sapiens DAOY cerebellar medulloblastoma cell line) - 2020/12/29 2020/12/29 rogid:cn8gYfKDpQc8J2ygnqny32sIyyU9606 rogid:XnBrmDaoz2JZQ66PCjfJsmaQ6209606 rigid:6EMs5+B89Q89RCR/2S2BG6PhH9E false tandem tag:n-n - - - psi-mi:"MI:0658"(multidimensional protein identification technology) psi-mi:"MI:0658"(multidimensional protein identification technology) uniprotkb:P48431 uniprotkb:Q9NXV2 intact:EBI-6124081|uniprotkb:Q14537|ensembl:ENSP00000323588 intact:EBI-1056857|uniprotkb:D3DU96|ensembl:ENSP00000301738 psi-mi:sox2_human(display_long)|uniprotkb:SOX2(gene name)|psi-mi:SOX2(display_short) psi-mi:kctd5_human(display_long)|uniprotkb:KCTD5(gene name)|psi-mi:KCTD5(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Cox et al. (2012) pubmed:23667531|imex:IM-28599 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-26574619|imex:IM-28599-5 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_003097.1|dip:DIP-59913N|ensembl:ENSG00000181449(gene)|ensembl:ENST00000325404(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001649"(osteoblast differentiation)|go:"GO:0001654"(eye development)|go:"GO:0001714"(endodermal cell fate specification)|go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006325"(chromatin organization)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0009611"(response to wounding)|go:"GO:0009653"(anatomical structure morphogenesis)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0021781"(glial cell fate commitment)|go:"GO:0021983"(pituitary gland development)|go:"GO:0021984"(adenohypophysis development)|go:"GO:0022409"(positive regulation of cell-cell adhesion)|go:"GO:0030154"(cell differentiation)|go:"GO:0030900"(forebrain development)|go:"GO:0035019"(somatic stem cell population maintenance)|go:"GO:0035198"(miRNA binding)|go:"GO:0042246"(tissue regeneration)|go:"GO:0043281"(regulation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0043410"(positive regulation of MAPK cascade)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045165"(cell fate commitment)|go:"GO:0045597"(positive regulation of cell differentiation)|go:"GO:0045665"(negative regulation of neuron differentiation)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048839"(inner ear development)|go:"GO:0050680"(negative regulation of epithelial cell proliferation)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0070848"(response to growth factor)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:0097150"(neuronal stem cell population maintenance)|interpro:IPR009071(High mobility group box, HMG)|interpro:IPR022097|interpro:IPR032643|interpro:IPR036910|mint:P48431|rcsb pdb:1O4X|rcsb pdb:2LE4|rcsb pdb:6T7B|rcsb pdb:6T90|rcsb pdb:6WX7|rcsb pdb:6WX8|rcsb pdb:6WX9|rcsb pdb:6YOV|reactome:R-HSA-2892245|reactome:R-HSA-2892247|reactome:R-HSA-3769402|reactome:R-HSA-452723|reactome:R-HSA-6785807|reactome:R-HSA-8986944 refseq:NP_061865.1|interpro:IPR011333(BTB/POZ fold)|mint:Q9NXV2|rcsb pdb:3DRX|rcsb pdb:3DRY|rcsb pdb:3DRZ|ensembl:ENSG00000167977(gene)|ensembl:ENST00000301738(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0031463"(Cul3-RING ubiquitin ligase complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0051260"(protein homooligomerization)|go:"GO:0097602"(cullin family protein binding)|interpro:IPR000210(BTB/POZ-like)|interpro:IPR003131(Potassium channel, voltage dependent, Kv, tetramerisation) go:"GO:0005634"(nucleus) - - figure legend:ST2 F2A|comment:proteins identified only in our induced samples in three MudPIT analyses with the more stringent BY-adjusted significance p<0.05|dataset:Brain Disease - Neurological Diseases & Disorders|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-daoy)|taxid:9606(Homo sapiens DAOY cerebellar medulloblastoma cell line) - 2020/12/29 2020/12/29 rogid:cn8gYfKDpQc8J2ygnqny32sIyyU9606 rogid:KzXA4jgTKUY/EE1ORX+nMLCPfro9606 rigid:6EMs5+B89Q89RCR/2S2BG6PhH9E false tandem tag:n-n - - - psi-mi:"MI:0658"(multidimensional protein identification technology) psi-mi:"MI:0658"(multidimensional protein identification technology) uniprotkb:P48431 uniprotkb:O14770 intact:EBI-6124081|uniprotkb:Q14537|ensembl:ENSP00000323588 intact:EBI-2804934|uniprotkb:Q96KI5|uniprotkb:Q9NRS3|uniprotkb:Q9NRS1|uniprotkb:Q9NRS2|uniprotkb:Q96KI4|ensembl:ENSP00000453793|uniprotkb:A6NJI5|uniprotkb:A8MWD5|uniprotkb:B3KP98|uniprotkb:B3KPQ6|uniprotkb:Q96DI2 psi-mi:sox2_human(display_long)|uniprotkb:SOX2(gene name)|psi-mi:SOX2(display_short) psi-mi:meis2_human(display_long)|uniprotkb:MRG1(gene name synonym)|uniprotkb:Meis1-related protein 1(gene name synonym)|uniprotkb:MEIS2(gene name)|psi-mi:MEIS2(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Cox et al. (2012) pubmed:23667531|imex:IM-28599 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-26574619|imex:IM-28599-5 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_003097.1|dip:DIP-59913N|ensembl:ENSG00000181449(gene)|ensembl:ENST00000325404(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001649"(osteoblast differentiation)|go:"GO:0001654"(eye development)|go:"GO:0001714"(endodermal cell fate specification)|go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006325"(chromatin organization)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0009611"(response to wounding)|go:"GO:0009653"(anatomical structure morphogenesis)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0021781"(glial cell fate commitment)|go:"GO:0021983"(pituitary gland development)|go:"GO:0021984"(adenohypophysis development)|go:"GO:0022409"(positive regulation of cell-cell adhesion)|go:"GO:0030154"(cell differentiation)|go:"GO:0030900"(forebrain development)|go:"GO:0035019"(somatic stem cell population maintenance)|go:"GO:0035198"(miRNA binding)|go:"GO:0042246"(tissue regeneration)|go:"GO:0043281"(regulation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0043410"(positive regulation of MAPK cascade)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045165"(cell fate commitment)|go:"GO:0045597"(positive regulation of cell differentiation)|go:"GO:0045665"(negative regulation of neuron differentiation)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048839"(inner ear development)|go:"GO:0050680"(negative regulation of epithelial cell proliferation)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0070848"(response to growth factor)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:0097150"(neuronal stem cell population maintenance)|interpro:IPR009071(High mobility group box, HMG)|interpro:IPR022097|interpro:IPR032643|interpro:IPR036910|mint:P48431|rcsb pdb:1O4X|rcsb pdb:2LE4|rcsb pdb:6T7B|rcsb pdb:6T90|rcsb pdb:6WX7|rcsb pdb:6WX8|rcsb pdb:6WX9|rcsb pdb:6YOV|reactome:R-HSA-2892245|reactome:R-HSA-2892247|reactome:R-HSA-3769402|reactome:R-HSA-452723|reactome:R-HSA-6785807|reactome:R-HSA-8986944 ensembl:ENSG00000134138(gene)|ensembl:ENST00000561208(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001654"(eye development)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007420"(brain development)|go:"GO:0008134"(transcription factor binding)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0008542"(visual learning)|go:"GO:0009612"(response to mechanical stimulus)|go:"GO:0009880"(embryonic pattern specification)|go:"GO:0009887"(animal organ morphogenesis)|go:"GO:0031016"(pancreas development)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045638"(negative regulation of myeloid cell differentiation)|go:"GO:0045931"(positive regulation of mitotic cell cycle)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0070848"(response to growth factor)|go:"GO:0110024"(positive regulation of cardiac muscle myoblast proliferation)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR001356(Homeobox)|interpro:IPR008422(Coprinus cinereus mating-type protein)|interpro:IPR009057(Homeodomain-like)|interpro:IPR032453|mint:O14770|rcsb pdb:3K2A|rcsb pdb:4XRM|rcsb pdb:5BNG|rcsb pdb:5EG0|refseq:NP_001207411.1|refseq:NP_733774.1|refseq:NP_733775.1|refseq:NP_733776.1|refseq:NP_733777.1|refseq:NP_002390.1|refseq:NP_758526.1|refseq:NP_758527.1|ensembl:ENST00000314177|ensembl:ENSP00000326296|ensembl:ENST00000338564|ensembl:ENSP00000341400|ensembl:ENST00000340545|ensembl:ENSP00000339549|ensembl:ENST00000397620|ensembl:ENSP00000380745|ensembl:ENST00000397624|ensembl:ENSP00000380749|ensembl:ENST00000424352|ensembl:ENSP00000404185|ensembl:ENST00000557796|ensembl:ENSP00000452693|ensembl:ENST00000559085|ensembl:ENSP00000453390|ensembl:ENST00000559561|ensembl:ENSP00000453497|ensembl:ENSP00000453793|refseq:XP_016877694.1|dip:DIP-61027N go:"GO:0005634"(nucleus) - - figure legend:ST2 F2A|comment:proteins identified only in our induced samples in three MudPIT analyses with the more stringent BY-adjusted significance p<0.05|dataset:Brain Disease - Neurological Diseases & Disorders|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-daoy)|taxid:9606(Homo sapiens DAOY cerebellar medulloblastoma cell line) - 2020/12/29 2020/12/29 rogid:cn8gYfKDpQc8J2ygnqny32sIyyU9606 rogid:dzZaH/NCkNWqc4N6ZVa+i5Knqrg9606 rigid:6EMs5+B89Q89RCR/2S2BG6PhH9E false tandem tag:n-n - - - psi-mi:"MI:0658"(multidimensional protein identification technology) psi-mi:"MI:0658"(multidimensional protein identification technology) uniprotkb:P48431 uniprotkb:Q01085 intact:EBI-6124081|uniprotkb:Q14537|ensembl:ENSP00000323588 intact:EBI-2820828|uniprotkb:A8K3T0|uniprotkb:A8K4L9|ensembl:ENSP00000394902 psi-mi:sox2_human(display_long)|uniprotkb:SOX2(gene name)|psi-mi:SOX2(display_short) psi-mi:tiar_human(display_long)|uniprotkb:TIAL1(gene name)|psi-mi:TIAL1(display_short)|uniprotkb:TIA-1-related protein(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Cox et al. (2012) pubmed:23667531|imex:IM-28599 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-26574619|imex:IM-28599-5 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_003097.1|dip:DIP-59913N|ensembl:ENSG00000181449(gene)|ensembl:ENST00000325404(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001649"(osteoblast differentiation)|go:"GO:0001654"(eye development)|go:"GO:0001714"(endodermal cell fate specification)|go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006325"(chromatin organization)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0009611"(response to wounding)|go:"GO:0009653"(anatomical structure morphogenesis)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0021781"(glial cell fate commitment)|go:"GO:0021983"(pituitary gland development)|go:"GO:0021984"(adenohypophysis development)|go:"GO:0022409"(positive regulation of cell-cell adhesion)|go:"GO:0030154"(cell differentiation)|go:"GO:0030900"(forebrain development)|go:"GO:0035019"(somatic stem cell population maintenance)|go:"GO:0035198"(miRNA binding)|go:"GO:0042246"(tissue regeneration)|go:"GO:0043281"(regulation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0043410"(positive regulation of MAPK cascade)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045165"(cell fate commitment)|go:"GO:0045597"(positive regulation of cell differentiation)|go:"GO:0045665"(negative regulation of neuron differentiation)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048839"(inner ear development)|go:"GO:0050680"(negative regulation of epithelial cell proliferation)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0070848"(response to growth factor)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:0097150"(neuronal stem cell population maintenance)|interpro:IPR009071(High mobility group box, HMG)|interpro:IPR022097|interpro:IPR032643|interpro:IPR036910|mint:P48431|rcsb pdb:1O4X|rcsb pdb:2LE4|rcsb pdb:6T7B|rcsb pdb:6T90|rcsb pdb:6WX7|rcsb pdb:6WX8|rcsb pdb:6WX9|rcsb pdb:6YOV|reactome:R-HSA-2892245|reactome:R-HSA-2892247|reactome:R-HSA-3769402|reactome:R-HSA-452723|reactome:R-HSA-6785807|reactome:R-HSA-8986944 refseq:NP_001029097.1|refseq:NP_003243.1|ensembl:ENSG00000151923(gene)|ensembl:ENST00000436547(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0003730"(mRNA 3'-UTR binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005764"(lysosome)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006915"(apoptotic process)|go:"GO:0006952"(defense response)|go:"GO:0007281"(germ cell development)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0010494"(cytoplasmic stress granule)|go:"GO:0017145"(stem cell division)|go:"GO:0035332"(positive regulation of hippo signaling)|go:"GO:0035925"(mRNA 3'-UTR AU-rich region binding)|go:"GO:1903231"(mRNA binding involved in posttranscriptional gene silencing)|go:"GO:1990904"(ribonucleoprotein complex)|go:"GO:2000637"(positive regulation of gene silencing by miRNA)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR003954(RNA recognition, region 1)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR034492|interpro:IPR034494|interpro:IPR034496|interpro:IPR035979|mint:Q01085|rcsb pdb:1X4G|rcsb pdb:2CQI|rcsb pdb:2DH7|reactome:R-HSA-6803529|dip:DIP-42425N go:"GO:0005634"(nucleus) - - figure legend:ST2 F2A|comment:proteins identified only in our induced samples in three MudPIT analyses with the more stringent BY-adjusted significance p<0.05|dataset:Brain Disease - Neurological Diseases & Disorders|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-daoy)|taxid:9606(Homo sapiens DAOY cerebellar medulloblastoma cell line) - 2020/12/29 2020/12/29 rogid:cn8gYfKDpQc8J2ygnqny32sIyyU9606 rogid:dKWzIWmR/JaCJwsOLUPG2Z1uhH89606 rigid:6EMs5+B89Q89RCR/2S2BG6PhH9E false tandem tag:n-n - - - psi-mi:"MI:0658"(multidimensional protein identification technology) psi-mi:"MI:0658"(multidimensional protein identification technology) uniprotkb:P48431 uniprotkb:O95817 intact:EBI-6124081|uniprotkb:Q14537|ensembl:ENSP00000323588 intact:EBI-747185|uniprotkb:Q3B763|uniprotkb:Q9NT20|uniprotkb:Q9P120|uniprotkb:A8K5L8|ensembl:ENSP00000358081 psi-mi:sox2_human(display_long)|uniprotkb:SOX2(gene name)|psi-mi:SOX2(display_short) psi-mi:bag3_human(display_long)|uniprotkb:Bcl-2-associated athanogene 3(gene name synonym)|uniprotkb:Bcl-2-binding protein Bis(gene name synonym)|uniprotkb:Docking protein CAIR-1(gene name synonym)|uniprotkb:BAG3(gene name)|psi-mi:BAG3(display_short)|uniprotkb:BIS(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Cox et al. (2012) pubmed:23667531|imex:IM-28599 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-26574619|imex:IM-28599-5 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_003097.1|dip:DIP-59913N|ensembl:ENSG00000181449(gene)|ensembl:ENST00000325404(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001649"(osteoblast differentiation)|go:"GO:0001654"(eye development)|go:"GO:0001714"(endodermal cell fate specification)|go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006325"(chromatin organization)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0009611"(response to wounding)|go:"GO:0009653"(anatomical structure morphogenesis)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0021781"(glial cell fate commitment)|go:"GO:0021983"(pituitary gland development)|go:"GO:0021984"(adenohypophysis development)|go:"GO:0022409"(positive regulation of cell-cell adhesion)|go:"GO:0030154"(cell differentiation)|go:"GO:0030900"(forebrain development)|go:"GO:0035019"(somatic stem cell population maintenance)|go:"GO:0035198"(miRNA binding)|go:"GO:0042246"(tissue regeneration)|go:"GO:0043281"(regulation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0043410"(positive regulation of MAPK cascade)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045165"(cell fate commitment)|go:"GO:0045597"(positive regulation of cell differentiation)|go:"GO:0045665"(negative regulation of neuron differentiation)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048839"(inner ear development)|go:"GO:0050680"(negative regulation of epithelial cell proliferation)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0070848"(response to growth factor)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:0097150"(neuronal stem cell population maintenance)|interpro:IPR009071(High mobility group box, HMG)|interpro:IPR022097|interpro:IPR032643|interpro:IPR036910|mint:P48431|rcsb pdb:1O4X|rcsb pdb:2LE4|rcsb pdb:6T7B|rcsb pdb:6T90|rcsb pdb:6WX7|rcsb pdb:6WX8|rcsb pdb:6WX9|rcsb pdb:6YOV|reactome:R-HSA-2892245|reactome:R-HSA-2892247|reactome:R-HSA-3769402|reactome:R-HSA-452723|reactome:R-HSA-6785807|reactome:R-HSA-8986944 refseq:NP_004272.2|ensembl:ENSG00000151929(gene)|ensembl:ENST00000369085(transcript)|go:"GO:0000045"(autophagosome assembly)|go:"GO:0000774"(adenyl-nucleotide exchange factor activity)|go:"GO:0001725"(stress fiber)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006457"(protein folding)|go:"GO:0007420"(brain development)|go:"GO:0008625"(extrinsic apoptotic signaling pathway via death domain receptors)|go:"GO:0010664"(negative regulation of striated muscle cell apoptotic process)|go:"GO:0016020"(membrane)|go:"GO:0016235"(aggresome)|go:"GO:0021510"(spinal cord development)|go:"GO:0030018"(Z disc)|go:"GO:0031072"(heat shock protein binding)|go:"GO:0034605"(cellular response to heat)|go:"GO:0034620"(cellular response to unfolded protein)|go:"GO:0042307"(positive regulation of protein import into nucleus)|go:"GO:0043005"(neuron projection)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045296"(cadherin binding)|go:"GO:0045505"(dynein intermediate chain binding)|go:"GO:0046716"(muscle cell cellular homeostasis)|go:"GO:0046827"(positive regulation of protein export from nucleus)|go:"GO:0050821"(protein stabilization)|go:"GO:0051087"(chaperone binding)|go:"GO:0061684"(chaperone-mediated autophagy)|go:"GO:0070842"(aggresome assembly)|go:"GO:0071260"(cellular response to mechanical stimulus)|go:"GO:0097192"(extrinsic apoptotic signaling pathway in absence of ligand)|go:"GO:0097201"(negative regulation of transcription from RNA polymerase II promoter in response to stress)|go:"GO:0098840"(protein transport along microtubule)|go:"GO:0140597"(protein carrier chaperone)|go:"GO:1903215"(negative regulation of protein targeting to mitochondrion)|go:"GO:1905337"(positive regulation of aggrephagy)|interpro:IPR001202(WW/Rsp5/WWP)|interpro:IPR003103(Apoptosis regulator Bcl-2 protein, BAG)|interpro:IPR036020|interpro:IPR036533|interpro:IPR039773|mint:O95817|reactome:R-HSA-3371453|go:"GO:0101031"(chaperone complex)|dip:DIP-41273N go:"GO:0005634"(nucleus) - - figure legend:ST2 F2A|comment:proteins identified only in our induced samples in three MudPIT analyses with the more stringent BY-adjusted significance p<0.05|dataset:Brain Disease - Neurological Diseases & Disorders|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-daoy)|taxid:9606(Homo sapiens DAOY cerebellar medulloblastoma cell line) - 2020/12/29 2020/12/29 rogid:cn8gYfKDpQc8J2ygnqny32sIyyU9606 rogid:Ld26VRSMJghXG/U98A76RijSDBc9606 rigid:6EMs5+B89Q89RCR/2S2BG6PhH9E false tandem tag:n-n - - - psi-mi:"MI:0658"(multidimensional protein identification technology) psi-mi:"MI:0658"(multidimensional protein identification technology) uniprotkb:P48431 uniprotkb:Q13610 intact:EBI-6124081|uniprotkb:Q14537|ensembl:ENSP00000323588 intact:EBI-1050630|uniprotkb:A8K3R6|ensembl:ENSP00000387365|uniprotkb:Q7Z3X9 psi-mi:sox2_human(display_long)|uniprotkb:SOX2(gene name)|psi-mi:SOX2(display_short) psi-mi:pwp1_human(display_long)|uniprotkb:Keratinocyte protein IEF SSP 9502(gene name synonym)|uniprotkb:PWP1(gene name)|psi-mi:PWP1(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Cox et al. (2012) pubmed:23667531|imex:IM-28599 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-26574619|imex:IM-28599-5 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_003097.1|dip:DIP-59913N|ensembl:ENSG00000181449(gene)|ensembl:ENST00000325404(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001649"(osteoblast differentiation)|go:"GO:0001654"(eye development)|go:"GO:0001714"(endodermal cell fate specification)|go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006325"(chromatin organization)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0009611"(response to wounding)|go:"GO:0009653"(anatomical structure morphogenesis)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0021781"(glial cell fate commitment)|go:"GO:0021983"(pituitary gland development)|go:"GO:0021984"(adenohypophysis development)|go:"GO:0022409"(positive regulation of cell-cell adhesion)|go:"GO:0030154"(cell differentiation)|go:"GO:0030900"(forebrain development)|go:"GO:0035019"(somatic stem cell population maintenance)|go:"GO:0035198"(miRNA binding)|go:"GO:0042246"(tissue regeneration)|go:"GO:0043281"(regulation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0043410"(positive regulation of MAPK cascade)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045165"(cell fate commitment)|go:"GO:0045597"(positive regulation of cell differentiation)|go:"GO:0045665"(negative regulation of neuron differentiation)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048839"(inner ear development)|go:"GO:0050680"(negative regulation of epithelial cell proliferation)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0070848"(response to growth factor)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:0097150"(neuronal stem cell population maintenance)|interpro:IPR009071(High mobility group box, HMG)|interpro:IPR022097|interpro:IPR032643|interpro:IPR036910|mint:P48431|rcsb pdb:1O4X|rcsb pdb:2LE4|rcsb pdb:6T7B|rcsb pdb:6T90|rcsb pdb:6WX7|rcsb pdb:6WX8|rcsb pdb:6WX9|rcsb pdb:6YOV|reactome:R-HSA-2892245|reactome:R-HSA-2892247|reactome:R-HSA-3769402|reactome:R-HSA-452723|reactome:R-HSA-6785807|reactome:R-HSA-8986944 refseq:NP_008993.1|refseq:NP_001304892.1|ensembl:ENSG00000136045(gene)|ensembl:ENST00000412830(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005694"(chromosome)|go:"GO:0005730"(nucleolus)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0006364"(rRNA processing)|go:"GO:0033140"(negative regulation of peptidyl-serine phosphorylation of STAT protein)|go:"GO:0034773"(histone H4-K20 trimethylation)|go:"GO:1901838"(positive regulation of transcription of nucleolar large rRNA by RNA polymerase I)|go:"GO:1990889"(H4K20me3 modified histone binding)|go:"GO:2000738"(positive regulation of stem cell differentiation)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019775|interpro:IPR020472|interpro:IPR036322|interpro:IPR044285|mint:Q13610 go:"GO:0005634"(nucleus) - - figure legend:ST2 F2A|comment:proteins identified only in our induced samples in three MudPIT analyses with the more stringent BY-adjusted significance p<0.05|dataset:Brain Disease - Neurological Diseases & Disorders|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-daoy)|taxid:9606(Homo sapiens DAOY cerebellar medulloblastoma cell line) - 2020/12/29 2020/12/29 rogid:cn8gYfKDpQc8J2ygnqny32sIyyU9606 rogid:3LMa4f6IxjpvEoh2Hyu0hHKkY789606 rigid:6EMs5+B89Q89RCR/2S2BG6PhH9E false tandem tag:n-n - - - psi-mi:"MI:0658"(multidimensional protein identification technology) psi-mi:"MI:0658"(multidimensional protein identification technology) uniprotkb:P48431 uniprotkb:P51398 intact:EBI-6124081|uniprotkb:Q14537|ensembl:ENSP00000323588 intact:EBI-355912|uniprotkb:Q13044|uniprotkb:Q96Q20|uniprotkb:Q68CT7|uniprotkb:B4DP59|uniprotkb:E7EM60|uniprotkb:B4DY62|ensembl:ENSP00000341692|ensembl:ENSP00000357320 psi-mi:sox2_human(display_long)|uniprotkb:SOX2(gene name)|psi-mi:SOX2(display_short) psi-mi:rt29_human(display_long)|uniprotkb:DAP3(gene name)|psi-mi:DAP3(display_short)|uniprotkb:MRPS29(gene name synonym)|uniprotkb:Death-associated protein 3(gene name synonym)|uniprotkb:Ionizing radiation resistance conferring protein(gene name synonym)|uniprotkb:Mitochondrial small ribosomal subunit protein mS29(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Cox et al. (2012) pubmed:23667531|imex:IM-28599 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-26574619|imex:IM-28599-5 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_003097.1|dip:DIP-59913N|ensembl:ENSG00000181449(gene)|ensembl:ENST00000325404(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001649"(osteoblast differentiation)|go:"GO:0001654"(eye development)|go:"GO:0001714"(endodermal cell fate specification)|go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006325"(chromatin organization)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0009611"(response to wounding)|go:"GO:0009653"(anatomical structure morphogenesis)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0021781"(glial cell fate commitment)|go:"GO:0021983"(pituitary gland development)|go:"GO:0021984"(adenohypophysis development)|go:"GO:0022409"(positive regulation of cell-cell adhesion)|go:"GO:0030154"(cell differentiation)|go:"GO:0030900"(forebrain development)|go:"GO:0035019"(somatic stem cell population maintenance)|go:"GO:0035198"(miRNA binding)|go:"GO:0042246"(tissue regeneration)|go:"GO:0043281"(regulation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0043410"(positive regulation of MAPK cascade)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045165"(cell fate commitment)|go:"GO:0045597"(positive regulation of cell differentiation)|go:"GO:0045665"(negative regulation of neuron differentiation)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048839"(inner ear development)|go:"GO:0050680"(negative regulation of epithelial cell proliferation)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0070848"(response to growth factor)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:0097150"(neuronal stem cell population maintenance)|interpro:IPR009071(High mobility group box, HMG)|interpro:IPR022097|interpro:IPR032643|interpro:IPR036910|mint:P48431|rcsb pdb:1O4X|rcsb pdb:2LE4|rcsb pdb:6T7B|rcsb pdb:6T90|rcsb pdb:6WX7|rcsb pdb:6WX8|rcsb pdb:6WX9|rcsb pdb:6YOV|reactome:R-HSA-2892245|reactome:R-HSA-2892247|reactome:R-HSA-3769402|reactome:R-HSA-452723|reactome:R-HSA-6785807|reactome:R-HSA-8986944 refseq:NP_001186778.1|refseq:NP_004623.1|refseq:NP_387506.1|refseq:NP_001186779.1|refseq:NP_001186780.1|refseq:XP_005245537.1|refseq:XP_005245538.1|ensembl:ENSG00000132676(gene)|ensembl:ENST00000343043(transcript)|ensembl:ENST00000368336(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005525"(GTP binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005763"(mitochondrial small ribosomal subunit)|go:"GO:0097190"(apoptotic signaling pathway)|interpro:IPR008092(Death associated protein 3)|interpro:IPR019368|interpro:IPR027417|mint:P51398|rcsb pdb:3J9M|rcsb pdb:6NU2|rcsb pdb:6NU3|rcsb pdb:6RW4|rcsb pdb:6RW5|rcsb pdb:6VLZ|rcsb pdb:6VMI|rcsb pdb:6ZM5|rcsb pdb:6ZM6|rcsb pdb:6ZS9|rcsb pdb:6ZSA|rcsb pdb:6ZSB|rcsb pdb:6ZSC|rcsb pdb:6ZSD|rcsb pdb:6ZSE|rcsb pdb:6ZSG|rcsb pdb:7A5F|rcsb pdb:7A5G|rcsb pdb:7A5I|rcsb pdb:7A5K|rcsb pdb:7L08|rcsb pdb:7OG4|reactome:R-HSA-5368286|reactome:R-HSA-5389840|reactome:R-HSA-5419276|refseq:XP_016857780.1|refseq:XP_016857781.1|refseq:XP_016857782.1 go:"GO:0005634"(nucleus) - - figure legend:ST2 F2A|comment:proteins identified only in our induced samples in three MudPIT analyses with the more stringent BY-adjusted significance p<0.05|dataset:Brain Disease - Neurological Diseases & Disorders|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-daoy)|taxid:9606(Homo sapiens DAOY cerebellar medulloblastoma cell line) - 2020/12/29 2020/12/29 rogid:cn8gYfKDpQc8J2ygnqny32sIyyU9606 rogid:xSIyqKH4F49Iu+AVuVThJWsi9EA9606 rigid:6EMs5+B89Q89RCR/2S2BG6PhH9E false tandem tag:n-n - - - psi-mi:"MI:0658"(multidimensional protein identification technology) psi-mi:"MI:0658"(multidimensional protein identification technology) uniprotkb:P48431 uniprotkb:Q86YP4 intact:EBI-6124081|uniprotkb:Q14537|ensembl:ENSP00000323588 intact:EBI-726224|uniprotkb:Q7L3J2|uniprotkb:Q96F28|uniprotkb:Q9NPU2|uniprotkb:Q9NXS1|uniprotkb:B5MC40|ensembl:ENSP00000351552|ensembl:ENSP00000353463 psi-mi:sox2_human(display_long)|uniprotkb:SOX2(gene name)|psi-mi:SOX2(display_short) psi-mi:p66a_human(display_long)|uniprotkb:GATA zinc finger domain-containing protein 2A(gene name synonym)|uniprotkb:GATAD2A(gene name)|psi-mi:GATAD2A(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Cox et al. (2012) pubmed:23667531|imex:IM-28599 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-26574619|imex:IM-28599-5 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_003097.1|dip:DIP-59913N|ensembl:ENSG00000181449(gene)|ensembl:ENST00000325404(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001649"(osteoblast differentiation)|go:"GO:0001654"(eye development)|go:"GO:0001714"(endodermal cell fate specification)|go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006325"(chromatin organization)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0009611"(response to wounding)|go:"GO:0009653"(anatomical structure morphogenesis)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0021781"(glial cell fate commitment)|go:"GO:0021983"(pituitary gland development)|go:"GO:0021984"(adenohypophysis development)|go:"GO:0022409"(positive regulation of cell-cell adhesion)|go:"GO:0030154"(cell differentiation)|go:"GO:0030900"(forebrain development)|go:"GO:0035019"(somatic stem cell population maintenance)|go:"GO:0035198"(miRNA binding)|go:"GO:0042246"(tissue regeneration)|go:"GO:0043281"(regulation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0043410"(positive regulation of MAPK cascade)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045165"(cell fate commitment)|go:"GO:0045597"(positive regulation of cell differentiation)|go:"GO:0045665"(negative regulation of neuron differentiation)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048839"(inner ear development)|go:"GO:0050680"(negative regulation of epithelial cell proliferation)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0070848"(response to growth factor)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:0097150"(neuronal stem cell population maintenance)|interpro:IPR009071(High mobility group box, HMG)|interpro:IPR022097|interpro:IPR032643|interpro:IPR036910|mint:P48431|rcsb pdb:1O4X|rcsb pdb:2LE4|rcsb pdb:6T7B|rcsb pdb:6T90|rcsb pdb:6WX7|rcsb pdb:6WX8|rcsb pdb:6WX9|rcsb pdb:6YOV|reactome:R-HSA-2892245|reactome:R-HSA-2892247|reactome:R-HSA-3769402|reactome:R-HSA-452723|reactome:R-HSA-6785807|reactome:R-HSA-8986944 refseq:NP_060130.3|refseq:NP_001287875.1|refseq:XP_011526407.1|ensembl:ENSG00000167491(gene)|ensembl:ENST00000358713(transcript)|ensembl:ENST00000360315(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006306"(DNA methylation)|go:"GO:0008270"(zinc ion binding)|go:"GO:0016581"(NuRD complex)|go:"GO:0016607"(nuclear speck)|go:"GO:0030674"(protein-macromolecule adaptor activity)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|interpro:IPR000679(Zinc finger, GATA-type)|interpro:IPR032346|interpro:IPR040386|mint:Q86YP4|rcsb pdb:2L2L|reactome:R-HSA-3214815|reactome:R-HSA-427389|reactome:R-HSA-6804758|reactome:R-HSA-73762|reactome:R-HSA-8943724|reactome:R-HSA-9679191|dip:DIP-36053N go:"GO:0005634"(nucleus) - - figure legend:ST2 F2A|comment:proteins identified only in our induced samples in three MudPIT analyses with the more stringent BY-adjusted significance p<0.05|dataset:Brain Disease - Neurological Diseases & Disorders|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-daoy)|taxid:9606(Homo sapiens DAOY cerebellar medulloblastoma cell line) - 2020/12/29 2020/12/29 rogid:cn8gYfKDpQc8J2ygnqny32sIyyU9606 rogid:s2G27yMihH9d7ny/v1GZ7aeTpDQ9606 rigid:6EMs5+B89Q89RCR/2S2BG6PhH9E false tandem tag:n-n - - - psi-mi:"MI:0658"(multidimensional protein identification technology) psi-mi:"MI:0658"(multidimensional protein identification technology) uniprotkb:P48431 uniprotkb:P19387 intact:EBI-6124081|uniprotkb:Q14537|ensembl:ENSP00000323588 intact:EBI-394729|uniprotkb:O15161|ensembl:ENSP00000219252 psi-mi:sox2_human(display_long)|uniprotkb:SOX2(gene name)|psi-mi:SOX2(display_short) psi-mi:rpb3_human(display_long)|uniprotkb:POLR2C(gene name)|psi-mi:POLR2C(display_short)|uniprotkb:A-152E5.7(orf name)|uniprotkb:DNA-directed RNA polymerase II subunit C(gene name synonym)|uniprotkb:DNA-directed RNA polymerase II 33 kDa polypeptide(gene name synonym)|uniprotkb:RPB31(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Cox et al. (2012) pubmed:23667531|imex:IM-28599 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-26574619|imex:IM-28599-5 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_003097.1|dip:DIP-59913N|ensembl:ENSG00000181449(gene)|ensembl:ENST00000325404(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001649"(osteoblast differentiation)|go:"GO:0001654"(eye development)|go:"GO:0001714"(endodermal cell fate specification)|go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006325"(chromatin organization)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0009611"(response to wounding)|go:"GO:0009653"(anatomical structure morphogenesis)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0021781"(glial cell fate commitment)|go:"GO:0021983"(pituitary gland development)|go:"GO:0021984"(adenohypophysis development)|go:"GO:0022409"(positive regulation of cell-cell adhesion)|go:"GO:0030154"(cell differentiation)|go:"GO:0030900"(forebrain development)|go:"GO:0035019"(somatic stem cell population maintenance)|go:"GO:0035198"(miRNA binding)|go:"GO:0042246"(tissue regeneration)|go:"GO:0043281"(regulation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0043410"(positive regulation of MAPK cascade)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045165"(cell fate commitment)|go:"GO:0045597"(positive regulation of cell differentiation)|go:"GO:0045665"(negative regulation of neuron differentiation)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048839"(inner ear development)|go:"GO:0050680"(negative regulation of epithelial cell proliferation)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0070848"(response to growth factor)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:0097150"(neuronal stem cell population maintenance)|interpro:IPR009071(High mobility group box, HMG)|interpro:IPR022097|interpro:IPR032643|interpro:IPR036910|mint:P48431|rcsb pdb:1O4X|rcsb pdb:2LE4|rcsb pdb:6T7B|rcsb pdb:6T90|rcsb pdb:6WX7|rcsb pdb:6WX8|rcsb pdb:6WX9|rcsb pdb:6YOV|reactome:R-HSA-2892245|reactome:R-HSA-2892247|reactome:R-HSA-3769402|reactome:R-HSA-452723|reactome:R-HSA-6785807|reactome:R-HSA-8986944 refseq:NP_116558.1|ensembl:ENSG00000102978(gene)|ensembl:ENST00000219252(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0003899"(DNA-directed 5'-3' RNA polymerase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005665"(RNA polymerase II, core complex)|go:"GO:0005829"(cytosol)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0046983"(protein dimerization activity)|interpro:IPR001514(DNA-directed RNA polymerase, 30-40 kDa subunit, conserved site)|interpro:IPR011262(DNA-directed RNA polymerase, insert)|interpro:IPR011263(DNA-directed RNA polymerase, RpoA/D/Rpb3-type)|interpro:IPR036603|interpro:IPR036643|mint:P19387|rcsb pdb:5IY6|rcsb pdb:5IY7|rcsb pdb:5IY8|rcsb pdb:5IY9|rcsb pdb:5IYA|rcsb pdb:5IYB|rcsb pdb:5IYC|rcsb pdb:5IYD|rcsb pdb:6DRD|rcsb pdb:6O9L|rcsb pdb:6XRE|rcsb pdb:7LBM|reactome:R-HSA-112382|reactome:R-HSA-113418|reactome:R-HSA-167152|reactome:R-HSA-167158|reactome:R-HSA-167160|reactome:R-HSA-167161|reactome:R-HSA-167162|reactome:R-HSA-167172|reactome:R-HSA-167200|reactome:R-HSA-167238|reactome:R-HSA-167242|reactome:R-HSA-167243|reactome:R-HSA-167246|reactome:R-HSA-167287|reactome:R-HSA-167290|reactome:R-HSA-168325|reactome:R-HSA-203927|reactome:R-HSA-5578749|reactome:R-HSA-5601884|reactome:R-HSA-5617472|reactome:R-HSA-674695|reactome:R-HSA-6781823|reactome:R-HSA-6781827|reactome:R-HSA-6782135|reactome:R-HSA-6782210|reactome:R-HSA-6796648|reactome:R-HSA-6803529|reactome:R-HSA-6807505|reactome:R-HSA-72086|reactome:R-HSA-72163|reactome:R-HSA-72165|reactome:R-HSA-72203|reactome:R-HSA-73776|reactome:R-HSA-73779|reactome:R-HSA-75953|reactome:R-HSA-75955|reactome:R-HSA-76042|reactome:R-HSA-77075|reactome:R-HSA-8851708|reactome:R-HSA-9018519|reactome:R-HSA-9670095|dip:DIP-32911N go:"GO:0005634"(nucleus) - - figure legend:ST2 F2A|comment:proteins identified only in our induced samples in three MudPIT analyses with the more stringent BY-adjusted significance p<0.05|dataset:Brain Disease - Neurological Diseases & Disorders|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-daoy)|taxid:9606(Homo sapiens DAOY cerebellar medulloblastoma cell line) - 2020/12/29 2020/12/29 rogid:cn8gYfKDpQc8J2ygnqny32sIyyU9606 rogid:UXFC+i+QqB2WRgL9OiYSQ66L36c9606 rigid:6EMs5+B89Q89RCR/2S2BG6PhH9E false tandem tag:n-n - - - psi-mi:"MI:0658"(multidimensional protein identification technology) psi-mi:"MI:0658"(multidimensional protein identification technology) uniprotkb:P48431 uniprotkb:Q9UJX6 intact:EBI-6124081|uniprotkb:Q14537|ensembl:ENSP00000323588 intact:EBI-396211|uniprotkb:Q5VSG1|uniprotkb:Q96DG5|uniprotkb:Q96GG4|uniprotkb:Q9P2E1|intact:EBI-28984882|ensembl:ENSP00000314004 psi-mi:sox2_human(display_long)|uniprotkb:SOX2(gene name)|psi-mi:SOX2(display_short) psi-mi:anc2_human(display_long)|uniprotkb:ANAPC2(gene name)|psi-mi:ANAPC2(display_short)|uniprotkb:APC2(gene name synonym)|uniprotkb:KIAA1406(gene name synonym)|uniprotkb:Cyclosome subunit 2(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Cox et al. (2012) pubmed:23667531|imex:IM-28599 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-26574619|imex:IM-28599-5 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_003097.1|dip:DIP-59913N|ensembl:ENSG00000181449(gene)|ensembl:ENST00000325404(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001649"(osteoblast differentiation)|go:"GO:0001654"(eye development)|go:"GO:0001714"(endodermal cell fate specification)|go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006325"(chromatin organization)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0009611"(response to wounding)|go:"GO:0009653"(anatomical structure morphogenesis)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0021781"(glial cell fate commitment)|go:"GO:0021983"(pituitary gland development)|go:"GO:0021984"(adenohypophysis development)|go:"GO:0022409"(positive regulation of cell-cell adhesion)|go:"GO:0030154"(cell differentiation)|go:"GO:0030900"(forebrain development)|go:"GO:0035019"(somatic stem cell population maintenance)|go:"GO:0035198"(miRNA binding)|go:"GO:0042246"(tissue regeneration)|go:"GO:0043281"(regulation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0043410"(positive regulation of MAPK cascade)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045165"(cell fate commitment)|go:"GO:0045597"(positive regulation of cell differentiation)|go:"GO:0045665"(negative regulation of neuron differentiation)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048839"(inner ear development)|go:"GO:0050680"(negative regulation of epithelial cell proliferation)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0070848"(response to growth factor)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:0097150"(neuronal stem cell population maintenance)|interpro:IPR009071(High mobility group box, HMG)|interpro:IPR022097|interpro:IPR032643|interpro:IPR036910|mint:P48431|rcsb pdb:1O4X|rcsb pdb:2LE4|rcsb pdb:6T7B|rcsb pdb:6T90|rcsb pdb:6WX7|rcsb pdb:6WX8|rcsb pdb:6WX9|rcsb pdb:6YOV|reactome:R-HSA-2892245|reactome:R-HSA-2892247|reactome:R-HSA-3769402|reactome:R-HSA-452723|reactome:R-HSA-6785807|reactome:R-HSA-8986944 refseq:NP_037498.1|ensembl:ENSP00000314004|dip:DIP-32957N|ensembl:ENSG00000176248(gene)|ensembl:ENST00000323927(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005680"(anaphase-promoting complex)|go:"GO:0005829"(cytosol)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0007049"(cell cycle)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0031915"(positive regulation of synaptic plasticity)|go:"GO:0045773"(positive regulation of axon extension)|go:"GO:0050775"(positive regulation of dendrite morphogenesis)|go:"GO:0051301"(cell division)|go:"GO:0070979"(protein K11-linked ubiquitination)|go:"GO:0090129"(positive regulation of synapse maturation)|interpro:IPR001373(Cullin, N-terminal region)|interpro:IPR014786(Anaphase promoting complex subunit 2)|interpro:IPR016158(Cullin homology)|interpro:IPR036317|interpro:IPR036388|interpro:IPR036390|interpro:IPR044554|mint:Q9UJX6|rcsb pdb:4UI9|rcsb pdb:4YII|rcsb pdb:5A31|rcsb pdb:5G04|rcsb pdb:5G05|rcsb pdb:5KHR|rcsb pdb:5KHU|rcsb pdb:5L9T|rcsb pdb:5L9U|rcsb pdb:5LCW|rcsb pdb:6NXK|rcsb pdb:6OB1|rcsb pdb:6Q6G|rcsb pdb:6Q6H|rcsb pdb:6TLJ|rcsb pdb:6TM5|rcsb pdb:6TNT|reactome:R-HSA-141430|reactome:R-HSA-174048|reactome:R-HSA-174084|reactome:R-HSA-174154|reactome:R-HSA-174178|reactome:R-HSA-174184|reactome:R-HSA-176407|reactome:R-HSA-176408|reactome:R-HSA-176409|reactome:R-HSA-176412|reactome:R-HSA-179409|reactome:R-HSA-2467813|reactome:R-HSA-2559582|reactome:R-HSA-69017|reactome:R-HSA-8853884|reactome:R-HSA-9687136|reactome:R-HSA-983168 go:"GO:0005634"(nucleus) - - figure legend:ST2 F2A|comment:proteins identified only in our induced samples in three MudPIT analyses with the more stringent BY-adjusted significance p<0.05|dataset:Brain Disease - Neurological Diseases & Disorders|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-daoy)|taxid:9606(Homo sapiens DAOY cerebellar medulloblastoma cell line) - 2020/12/29 2020/12/29 rogid:cn8gYfKDpQc8J2ygnqny32sIyyU9606 rogid:PVV9qYjevihqygZjLzBflQ0Ob409606 rigid:6EMs5+B89Q89RCR/2S2BG6PhH9E false tandem tag:n-n - - - psi-mi:"MI:0658"(multidimensional protein identification technology) psi-mi:"MI:0658"(multidimensional protein identification technology) uniprotkb:P48431 uniprotkb:Q14865 intact:EBI-6124081|uniprotkb:Q14537|ensembl:ENSP00000323588 intact:EBI-1210388|uniprotkb:B4DLB3|uniprotkb:Q05DG6|uniprotkb:Q32Q59|uniprotkb:Q6NZ42|uniprotkb:Q5VST4|uniprotkb:Q7Z3M4|uniprotkb:Q8N421|uniprotkb:Q9H786|ensembl:ENSP00000279873 psi-mi:sox2_human(display_long)|uniprotkb:SOX2(gene name)|psi-mi:SOX2(display_short) psi-mi:ari5b_human(display_long)|uniprotkb:ARID5B(gene name)|psi-mi:ARID5B(display_short)|uniprotkb:DESRT(gene name synonym)|uniprotkb:MRF2(gene name synonym)|uniprotkb:MRF1-like protein(gene name synonym)|uniprotkb:Modulator recognition factor 2(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Cox et al. (2012) pubmed:23667531|imex:IM-28599 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-26574619|imex:IM-28599-5 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_003097.1|dip:DIP-59913N|ensembl:ENSG00000181449(gene)|ensembl:ENST00000325404(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001649"(osteoblast differentiation)|go:"GO:0001654"(eye development)|go:"GO:0001714"(endodermal cell fate specification)|go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006325"(chromatin organization)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0009611"(response to wounding)|go:"GO:0009653"(anatomical structure morphogenesis)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0021781"(glial cell fate commitment)|go:"GO:0021983"(pituitary gland development)|go:"GO:0021984"(adenohypophysis development)|go:"GO:0022409"(positive regulation of cell-cell adhesion)|go:"GO:0030154"(cell differentiation)|go:"GO:0030900"(forebrain development)|go:"GO:0035019"(somatic stem cell population maintenance)|go:"GO:0035198"(miRNA binding)|go:"GO:0042246"(tissue regeneration)|go:"GO:0043281"(regulation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0043410"(positive regulation of MAPK cascade)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045165"(cell fate commitment)|go:"GO:0045597"(positive regulation of cell differentiation)|go:"GO:0045665"(negative regulation of neuron differentiation)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048839"(inner ear development)|go:"GO:0050680"(negative regulation of epithelial cell proliferation)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0070848"(response to growth factor)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:0097150"(neuronal stem cell population maintenance)|interpro:IPR009071(High mobility group box, HMG)|interpro:IPR022097|interpro:IPR032643|interpro:IPR036910|mint:P48431|rcsb pdb:1O4X|rcsb pdb:2LE4|rcsb pdb:6T7B|rcsb pdb:6T90|rcsb pdb:6WX7|rcsb pdb:6WX8|rcsb pdb:6WX9|rcsb pdb:6YOV|reactome:R-HSA-2892245|reactome:R-HSA-2892247|reactome:R-HSA-3769402|reactome:R-HSA-452723|reactome:R-HSA-6785807|reactome:R-HSA-8986944 refseq:NP_115575.1|refseq:NP_001231567.1|ensembl:ENSG00000150347(gene)|ensembl:ENST00000279873(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0001822"(kidney development)|go:"GO:0001889"(liver development)|go:"GO:0003677"(DNA binding)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006807"(nitrogen compound metabolic process)|go:"GO:0008584"(male gonad development)|go:"GO:0008585"(female gonad development)|go:"GO:0009791"(post-embryonic development)|go:"GO:0010761"(fibroblast migration)|go:"GO:0030325"(adrenal gland development)|go:"GO:0035264"(multicellular organism growth)|go:"GO:0045444"(fat cell differentiation)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0048008"(platelet-derived growth factor receptor signaling pathway)|go:"GO:0048468"(cell development)|go:"GO:0048644"(muscle organ morphogenesis)|go:"GO:0048705"(skeletal system morphogenesis)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0060021"(roof of mouth development)|go:"GO:0060325"(face morphogenesis)|go:"GO:0060612"(adipose tissue development)|go:"GO:0060613"(fat pad development)|go:"GO:1990830"(cellular response to leukemia inhibitory factor)|interpro:IPR001606(AT-rich interaction region)|interpro:IPR030408|interpro:IPR036431|mint:Q14865|rcsb pdb:1IG6|rcsb pdb:2OEH|reactome:R-HSA-3214842|go:"GO:0005654"(nucleoplasm) go:"GO:0005634"(nucleus) - - figure legend:ST2 F2A|comment:proteins identified only in our induced samples in three MudPIT analyses with the more stringent BY-adjusted significance p<0.05|dataset:Brain Disease - Neurological Diseases & Disorders|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-daoy)|taxid:9606(Homo sapiens DAOY cerebellar medulloblastoma cell line) - 2020/12/29 2020/12/29 rogid:cn8gYfKDpQc8J2ygnqny32sIyyU9606 rogid:B6FNUWNl796yE+jX/0cAknrAkuo9606 rigid:6EMs5+B89Q89RCR/2S2BG6PhH9E false tandem tag:n-n - - - psi-mi:"MI:0658"(multidimensional protein identification technology) psi-mi:"MI:0658"(multidimensional protein identification technology) uniprotkb:P48431 uniprotkb:Q92973 intact:EBI-6124081|uniprotkb:Q14537|ensembl:ENSP00000323588 intact:EBI-286693|intact:EBI-1760498|uniprotkb:Q92957|uniprotkb:Q92975|intact:EBI-1965561|uniprotkb:B4DVC6|ensembl:ENSP00000336712 psi-mi:sox2_human(display_long)|uniprotkb:SOX2(gene name)|psi-mi:SOX2(display_short) psi-mi:tnpo1_human(display_long)|uniprotkb:TRN(gene name synonym)|uniprotkb:TNPO1(gene name)|psi-mi:TNPO1(display_short)|uniprotkb:KPNB2(gene name synonym)|uniprotkb:MIP1(gene name synonym)|uniprotkb:Importin beta-2(gene name synonym)|uniprotkb:Karyopherin beta-2(gene name synonym)|uniprotkb:M9 region interaction protein(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Cox et al. (2012) pubmed:23667531|imex:IM-28599 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-26574619|imex:IM-28599-5 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_003097.1|dip:DIP-59913N|ensembl:ENSG00000181449(gene)|ensembl:ENST00000325404(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001649"(osteoblast differentiation)|go:"GO:0001654"(eye development)|go:"GO:0001714"(endodermal cell fate specification)|go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006325"(chromatin organization)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0009611"(response to wounding)|go:"GO:0009653"(anatomical structure morphogenesis)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0021781"(glial cell fate commitment)|go:"GO:0021983"(pituitary gland development)|go:"GO:0021984"(adenohypophysis development)|go:"GO:0022409"(positive regulation of cell-cell adhesion)|go:"GO:0030154"(cell differentiation)|go:"GO:0030900"(forebrain development)|go:"GO:0035019"(somatic stem cell population maintenance)|go:"GO:0035198"(miRNA binding)|go:"GO:0042246"(tissue regeneration)|go:"GO:0043281"(regulation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0043410"(positive regulation of MAPK cascade)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045165"(cell fate commitment)|go:"GO:0045597"(positive regulation of cell differentiation)|go:"GO:0045665"(negative regulation of neuron differentiation)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048839"(inner ear development)|go:"GO:0050680"(negative regulation of epithelial cell proliferation)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0070848"(response to growth factor)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:0097150"(neuronal stem cell population maintenance)|interpro:IPR009071(High mobility group box, HMG)|interpro:IPR022097|interpro:IPR032643|interpro:IPR036910|mint:P48431|rcsb pdb:1O4X|rcsb pdb:2LE4|rcsb pdb:6T7B|rcsb pdb:6T90|rcsb pdb:6WX7|rcsb pdb:6WX8|rcsb pdb:6WX9|rcsb pdb:6YOV|reactome:R-HSA-2892245|reactome:R-HSA-2892247|reactome:R-HSA-3769402|reactome:R-HSA-452723|reactome:R-HSA-6785807|reactome:R-HSA-8986944 refseq:NP_002261.3|refseq:NP_694858.1|refseq:XP_005248557.1|dip:DIP-29335N|ensembl:ENSG00000083312(gene)|ensembl:ENST00000337273(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005929"(cilium)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0008139"(nuclear localization sequence binding)|go:"GO:0031267"(small GTPase binding)|go:"GO:0061608"(nuclear import signal receptor activity)|go:"GO:0070062"(extracellular exosome)|interpro:IPR001494(Importin-beta, N-terminal)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR040122|mint:Q92973|rcsb pdb:1QBK|rcsb pdb:2H4M|rcsb pdb:2OT8|rcsb pdb:2QMR|rcsb pdb:2Z5J|rcsb pdb:2Z5K|rcsb pdb:2Z5M|rcsb pdb:2Z5N|rcsb pdb:2Z5O|rcsb pdb:4FDD|rcsb pdb:4FQ3|rcsb pdb:4JLQ|rcsb pdb:4OO6|rcsb pdb:5J3V|rcsb pdb:5TQC|rcsb pdb:5YVG|rcsb pdb:5YVH|rcsb pdb:5YVI|rcsb pdb:7CYL|reactome:R-HSA-450513|reactome:R-HSA-5620924|reactome:R-HSA-9615933 go:"GO:0005634"(nucleus) - - figure legend:ST2 F2A|comment:proteins identified only in our induced samples in three MudPIT analyses with the more stringent BY-adjusted significance p<0.05|dataset:Brain Disease - Neurological Diseases & Disorders|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-daoy)|taxid:9606(Homo sapiens DAOY cerebellar medulloblastoma cell line) - 2020/12/29 2020/12/29 rogid:cn8gYfKDpQc8J2ygnqny32sIyyU9606 rogid:n8Q3n1rmTiJAp6f8DBcBV6j6lac9606 rigid:6EMs5+B89Q89RCR/2S2BG6PhH9E false tandem tag:n-n - - - psi-mi:"MI:0658"(multidimensional protein identification technology) psi-mi:"MI:0658"(multidimensional protein identification technology) uniprotkb:P48431 uniprotkb:Q9Y221 intact:EBI-6124081|uniprotkb:Q14537|ensembl:ENSP00000323588 intact:EBI-749003|uniprotkb:Q9NZZ0|uniprotkb:B2RD04|ensembl:ENSP00000254940 psi-mi:sox2_human(display_long)|uniprotkb:SOX2(gene name)|psi-mi:SOX2(display_short) psi-mi:nip7_human(display_long)|uniprotkb:KD93(gene name synonym)|uniprotkb:NIP7(gene name)|psi-mi:NIP7(display_short)|uniprotkb:Nucleolar pre-rRNA processing protein NIP7(gene name synonym)|uniprotkb:CGI-37(orf name)|uniprotkb:HSPC031(orf name)|uniprotkb:HSPC180(orf name)|uniprotkb:OK/SW-cl.76(orf name)|uniprotkb:OK/SW-cl.78(orf name) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Cox et al. (2012) pubmed:23667531|imex:IM-28599 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-26574619|imex:IM-28599-5 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_003097.1|dip:DIP-59913N|ensembl:ENSG00000181449(gene)|ensembl:ENST00000325404(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001649"(osteoblast differentiation)|go:"GO:0001654"(eye development)|go:"GO:0001714"(endodermal cell fate specification)|go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006325"(chromatin organization)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0009611"(response to wounding)|go:"GO:0009653"(anatomical structure morphogenesis)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0021781"(glial cell fate commitment)|go:"GO:0021983"(pituitary gland development)|go:"GO:0021984"(adenohypophysis development)|go:"GO:0022409"(positive regulation of cell-cell adhesion)|go:"GO:0030154"(cell differentiation)|go:"GO:0030900"(forebrain development)|go:"GO:0035019"(somatic stem cell population maintenance)|go:"GO:0035198"(miRNA binding)|go:"GO:0042246"(tissue regeneration)|go:"GO:0043281"(regulation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0043410"(positive regulation of MAPK cascade)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045165"(cell fate commitment)|go:"GO:0045597"(positive regulation of cell differentiation)|go:"GO:0045665"(negative regulation of neuron differentiation)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048839"(inner ear development)|go:"GO:0050680"(negative regulation of epithelial cell proliferation)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0070848"(response to growth factor)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:0097150"(neuronal stem cell population maintenance)|interpro:IPR009071(High mobility group box, HMG)|interpro:IPR022097|interpro:IPR032643|interpro:IPR036910|mint:P48431|rcsb pdb:1O4X|rcsb pdb:2LE4|rcsb pdb:6T7B|rcsb pdb:6T90|rcsb pdb:6WX7|rcsb pdb:6WX8|rcsb pdb:6WX9|rcsb pdb:6YOV|reactome:R-HSA-2892245|reactome:R-HSA-2892247|reactome:R-HSA-3769402|reactome:R-HSA-452723|reactome:R-HSA-6785807|reactome:R-HSA-8986944 refseq:NP_001186363.1|refseq:NP_057185.1|ensembl:ENSG00000132603(gene)|ensembl:ENST00000254940(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0030687"(preribosome, large subunit precursor)|go:"GO:0042255"(ribosome assembly)|go:"GO:0042273"(ribosomal large subunit biogenesis)|interpro:IPR002478(PUA)|interpro:IPR005155(Ribosome biogenesis factor NIP7-like)|interpro:IPR015947(PUA-like)|interpro:IPR016686(Ribosome biogenesis factor, NIP7)|interpro:IPR036974|interpro:IPR040598|mint:Q9Y221|rcsb pdb:1SQW|rcsb pdb:1T5Y|reactome:R-HSA-6791226 go:"GO:0005634"(nucleus) - - figure legend:ST2 F2A|comment:proteins identified only in our induced samples in three MudPIT analyses with the more stringent BY-adjusted significance p<0.05|dataset:Brain Disease - Neurological Diseases & Disorders|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-daoy)|taxid:9606(Homo sapiens DAOY cerebellar medulloblastoma cell line) - 2020/12/29 2020/12/29 rogid:cn8gYfKDpQc8J2ygnqny32sIyyU9606 rogid:912ZyupB0CxH5w23chPh3IIICmY9606 rigid:6EMs5+B89Q89RCR/2S2BG6PhH9E false tandem tag:n-n - - - psi-mi:"MI:0658"(multidimensional protein identification technology) psi-mi:"MI:0658"(multidimensional protein identification technology) uniprotkb:P48431 uniprotkb:Q16206 intact:EBI-6124081|uniprotkb:Q14537|ensembl:ENSP00000323588 intact:EBI-744159|uniprotkb:Q5VTJ1|uniprotkb:Q5VTJ2|uniprotkb:Q8WUX0|uniprotkb:Q9NTP6|uniprotkb:Q9UH82|intact:EBI-2623308|uniprotkb:A8K197|uniprotkb:A8K1C2|ensembl:ENSP00000337146|ensembl:ENSP00000359965 psi-mi:sox2_human(display_long)|uniprotkb:SOX2(gene name)|psi-mi:SOX2(display_short) psi-mi:enox2_human(display_long)|uniprotkb:Tumor-associated hydroquinone oxidase(gene name synonym)|uniprotkb:Cytosolic ovarian carcinoma antigen 1(gene name synonym)|uniprotkb:APK1 antigen(gene name synonym)|uniprotkb:ENOX2(gene name)|psi-mi:ENOX2(display_short)|uniprotkb:COVA1(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Cox et al. (2012) pubmed:23667531|imex:IM-28599 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-26574619|imex:IM-28599-5 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_003097.1|dip:DIP-59913N|ensembl:ENSG00000181449(gene)|ensembl:ENST00000325404(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001649"(osteoblast differentiation)|go:"GO:0001654"(eye development)|go:"GO:0001714"(endodermal cell fate specification)|go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006325"(chromatin organization)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0009611"(response to wounding)|go:"GO:0009653"(anatomical structure morphogenesis)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0021781"(glial cell fate commitment)|go:"GO:0021983"(pituitary gland development)|go:"GO:0021984"(adenohypophysis development)|go:"GO:0022409"(positive regulation of cell-cell adhesion)|go:"GO:0030154"(cell differentiation)|go:"GO:0030900"(forebrain development)|go:"GO:0035019"(somatic stem cell population maintenance)|go:"GO:0035198"(miRNA binding)|go:"GO:0042246"(tissue regeneration)|go:"GO:0043281"(regulation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0043410"(positive regulation of MAPK cascade)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045165"(cell fate commitment)|go:"GO:0045597"(positive regulation of cell differentiation)|go:"GO:0045665"(negative regulation of neuron differentiation)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048839"(inner ear development)|go:"GO:0050680"(negative regulation of epithelial cell proliferation)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0070848"(response to growth factor)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:0097150"(neuronal stem cell population maintenance)|interpro:IPR009071(High mobility group box, HMG)|interpro:IPR022097|interpro:IPR032643|interpro:IPR036910|mint:P48431|rcsb pdb:1O4X|rcsb pdb:2LE4|rcsb pdb:6T7B|rcsb pdb:6T90|rcsb pdb:6WX7|rcsb pdb:6WX8|rcsb pdb:6WX9|rcsb pdb:6YOV|reactome:R-HSA-2892245|reactome:R-HSA-2892247|reactome:R-HSA-3769402|reactome:R-HSA-452723|reactome:R-HSA-6785807|reactome:R-HSA-8986944 refseq:NP_006366.2|refseq:NP_872114.1|refseq:XP_011529549.1|refseq:XP_011529551.1|refseq:XP_011529553.1|refseq:NP_001268665.1|refseq:XP_005262411.1|mint:Q16206|interpro:IPR038876|ensembl:ENST00000338144(transcript)|ensembl:ENST00000370927(transcript)|go:"GO:0003676"(nucleic acid binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005829"(cytosol)|go:"GO:0007624"(ultradian rhythm)|go:"GO:0009897"(external side of plasma membrane)|go:"GO:0015035"(protein-disulfide reductase activity)|go:"GO:0022900"(electron transport chain)|go:"GO:0040008"(regulation of growth)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR034140|interpro:IPR035979|ensembl:ENSG00000165675(gene)|refseq:XP_016884715.1|refseq:XP_016884716.1|refseq:XP_016884717.1 go:"GO:0005634"(nucleus) - - figure legend:ST2 F2A|comment:proteins identified only in our induced samples in three MudPIT analyses with the more stringent BY-adjusted significance p<0.05|dataset:Brain Disease - Neurological Diseases & Disorders|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-daoy)|taxid:9606(Homo sapiens DAOY cerebellar medulloblastoma cell line) - 2020/12/29 2020/12/29 rogid:cn8gYfKDpQc8J2ygnqny32sIyyU9606 rogid:nqvZJv5GYe49nv+r4Bda6aRZ/mU9606 rigid:6EMs5+B89Q89RCR/2S2BG6PhH9E false tandem tag:n-n - - - psi-mi:"MI:0658"(multidimensional protein identification technology) psi-mi:"MI:0658"(multidimensional protein identification technology) uniprotkb:P48431 uniprotkb:Q9BYN8 intact:EBI-6124081|uniprotkb:Q14537|ensembl:ENSP00000323588 intact:EBI-721378|uniprotkb:Q96Q58|ensembl:ENSP00000369682 psi-mi:sox2_human(display_long)|uniprotkb:SOX2(gene name)|psi-mi:SOX2(display_short) psi-mi:rt26_human(display_long)|uniprotkb:28S ribosomal protein S13, mitochondrial(gene name synonym)|uniprotkb:MRPS26(gene name)|psi-mi:MRPS26(display_short)|uniprotkb:RPMS13(gene name synonym)|uniprotkb:C20orf193(gene name synonym)|uniprotkb:Mitochondrial small ribosomal subunit protein mS26(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Cox et al. (2012) pubmed:23667531|imex:IM-28599 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-26574619|imex:IM-28599-5 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_003097.1|dip:DIP-59913N|ensembl:ENSG00000181449(gene)|ensembl:ENST00000325404(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001649"(osteoblast differentiation)|go:"GO:0001654"(eye development)|go:"GO:0001714"(endodermal cell fate specification)|go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006325"(chromatin organization)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0009611"(response to wounding)|go:"GO:0009653"(anatomical structure morphogenesis)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0021781"(glial cell fate commitment)|go:"GO:0021983"(pituitary gland development)|go:"GO:0021984"(adenohypophysis development)|go:"GO:0022409"(positive regulation of cell-cell adhesion)|go:"GO:0030154"(cell differentiation)|go:"GO:0030900"(forebrain development)|go:"GO:0035019"(somatic stem cell population maintenance)|go:"GO:0035198"(miRNA binding)|go:"GO:0042246"(tissue regeneration)|go:"GO:0043281"(regulation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0043410"(positive regulation of MAPK cascade)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045165"(cell fate commitment)|go:"GO:0045597"(positive regulation of cell differentiation)|go:"GO:0045665"(negative regulation of neuron differentiation)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048839"(inner ear development)|go:"GO:0050680"(negative regulation of epithelial cell proliferation)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0070848"(response to growth factor)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:0097150"(neuronal stem cell population maintenance)|interpro:IPR009071(High mobility group box, HMG)|interpro:IPR022097|interpro:IPR032643|interpro:IPR036910|mint:P48431|rcsb pdb:1O4X|rcsb pdb:2LE4|rcsb pdb:6T7B|rcsb pdb:6T90|rcsb pdb:6WX7|rcsb pdb:6WX8|rcsb pdb:6WX9|rcsb pdb:6YOV|reactome:R-HSA-2892245|reactome:R-HSA-2892247|reactome:R-HSA-3769402|reactome:R-HSA-452723|reactome:R-HSA-6785807|reactome:R-HSA-8986944 refseq:NP_110438.1|rcsb pdb:3J9M|rcsb pdb:6NU2|rcsb pdb:6NU3|rcsb pdb:6RW4|rcsb pdb:6RW5|rcsb pdb:6VLZ|rcsb pdb:6VMI|rcsb pdb:6ZM5|rcsb pdb:6ZM6|rcsb pdb:6ZS9|rcsb pdb:6ZSA|rcsb pdb:6ZSB|rcsb pdb:6ZSC|rcsb pdb:6ZSD|rcsb pdb:6ZSE|rcsb pdb:6ZSG|rcsb pdb:7A5F|rcsb pdb:7A5G|rcsb pdb:7A5I|rcsb pdb:7A5K|rcsb pdb:7L08|rcsb pdb:7OG4|reactome:R-HSA-5368286|reactome:R-HSA-5389840|reactome:R-HSA-5419276|ensembl:ENSG00000125901(gene)|ensembl:ENST00000380325(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005763"(mitochondrial small ribosomal subunit)|go:"GO:0042769"(obsolete DNA damage response, detection of DNA damage)|interpro:IPR026140|mint:Q9BYN8 go:"GO:0005634"(nucleus) - - figure legend:ST2 F2A|comment:proteins identified only in our induced samples in three MudPIT analyses with the more stringent BY-adjusted significance p<0.05|dataset:Brain Disease - Neurological Diseases & Disorders|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-daoy)|taxid:9606(Homo sapiens DAOY cerebellar medulloblastoma cell line) - 2020/12/29 2020/12/29 rogid:cn8gYfKDpQc8J2ygnqny32sIyyU9606 rogid:ZygMazfhjHbx+aFhRkeG87c4L6E9606 rigid:6EMs5+B89Q89RCR/2S2BG6PhH9E false tandem tag:n-n - - - psi-mi:"MI:0658"(multidimensional protein identification technology) psi-mi:"MI:0658"(multidimensional protein identification technology) uniprotkb:P48431 uniprotkb:Q13330 intact:EBI-6124081|uniprotkb:Q14537|ensembl:ENSP00000323588 intact:EBI-714236|uniprotkb:Q8NFI8|uniprotkb:Q96GI8|uniprotkb:A5PLK4|intact:EBI-28976623|ensembl:ENSP00000333633|uniprotkb:Q86SW2 psi-mi:sox2_human(display_long)|uniprotkb:SOX2(gene name)|psi-mi:SOX2(display_short) psi-mi:mta1_human(display_long)|uniprotkb:MTA1(gene name)|psi-mi:MTA1(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Cox et al. (2012) pubmed:23667531|imex:IM-28599 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-26574619|imex:IM-28599-5 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_003097.1|dip:DIP-59913N|ensembl:ENSG00000181449(gene)|ensembl:ENST00000325404(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001649"(osteoblast differentiation)|go:"GO:0001654"(eye development)|go:"GO:0001714"(endodermal cell fate specification)|go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006325"(chromatin organization)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0009611"(response to wounding)|go:"GO:0009653"(anatomical structure morphogenesis)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0021781"(glial cell fate commitment)|go:"GO:0021983"(pituitary gland development)|go:"GO:0021984"(adenohypophysis development)|go:"GO:0022409"(positive regulation of cell-cell adhesion)|go:"GO:0030154"(cell differentiation)|go:"GO:0030900"(forebrain development)|go:"GO:0035019"(somatic stem cell population maintenance)|go:"GO:0035198"(miRNA binding)|go:"GO:0042246"(tissue regeneration)|go:"GO:0043281"(regulation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0043410"(positive regulation of MAPK cascade)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045165"(cell fate commitment)|go:"GO:0045597"(positive regulation of cell differentiation)|go:"GO:0045665"(negative regulation of neuron differentiation)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048839"(inner ear development)|go:"GO:0050680"(negative regulation of epithelial cell proliferation)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0070848"(response to growth factor)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:0097150"(neuronal stem cell population maintenance)|interpro:IPR009071(High mobility group box, HMG)|interpro:IPR022097|interpro:IPR032643|interpro:IPR036910|mint:P48431|rcsb pdb:1O4X|rcsb pdb:2LE4|rcsb pdb:6T7B|rcsb pdb:6T90|rcsb pdb:6WX7|rcsb pdb:6WX8|rcsb pdb:6WX9|rcsb pdb:6YOV|reactome:R-HSA-2892245|reactome:R-HSA-2892247|reactome:R-HSA-3769402|reactome:R-HSA-452723|reactome:R-HSA-6785807|reactome:R-HSA-8986944 refseq:NP_001190187.1|refseq:NP_004680.2|ensembl:ENSP00000333633|ensembl:ENST00000405646|ensembl:ENSP00000384180|ensembl:ENST00000438610|ensembl:ENSP00000393438|ensembl:ENSG00000182979(gene)|ensembl:ENST00000331320(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0003714"(transcription corepressor activity)|reactome:R-HSA-427389|reactome:R-HSA-73762|reactome:R-HSA-8943724|reactome:R-HSA-9679191|reactome:R-HSA-3232118|go:"GO:0005635"(nuclear envelope)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005874"(microtubule)|go:"GO:0006302"(double-strand break repair)|go:"GO:0007165"(signal transduction)|go:"GO:0008270"(zinc ion binding)|go:"GO:0010212"(response to ionizing radiation)|go:"GO:0016575"(histone deacetylation)|go:"GO:0016581"(NuRD complex)|go:"GO:0032922"(circadian regulation of gene expression)|go:"GO:0040029"(regulation of gene expression, epigenetic)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0043153"(entrainment of circadian clock by photoperiod)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0005634"(nucleus)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:1902499"(positive regulation of protein autoubiquitination)|interpro:IPR000679(Zinc finger, GATA-type)|interpro:IPR000949(ELM2)|interpro:IPR001005(SANT, DNA-binding)|interpro:IPR001025(Bromo adjacent region)|interpro:IPR009057(Homeodomain-like)|interpro:IPR017884|interpro:IPR017930|interpro:IPR035170|interpro:IPR040138|mint:Q13330|rcsb pdb:4BKX|rcsb pdb:4PBY|rcsb pdb:4PBZ|rcsb pdb:4PC0|rcsb pdb:5FXY|rcsb pdb:5ICN|rcsb pdb:6G16|rcsb pdb:6ZRC|rcsb pdb:6ZRD|rcsb pdb:7AO8|go:"GO:0045475"(locomotor rhythm)|rcsb pdb:7AO9|rcsb pdb:7AOA|reactome:R-HSA-3214815|dip:DIP-41751N go:"GO:0005634"(nucleus) - - figure legend:ST2 F2A|comment:proteins identified only in our induced samples in three MudPIT analyses with the more stringent BY-adjusted significance p<0.05|dataset:Brain Disease - Neurological Diseases & Disorders|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-daoy)|taxid:9606(Homo sapiens DAOY cerebellar medulloblastoma cell line) - 2020/12/29 2020/12/29 rogid:cn8gYfKDpQc8J2ygnqny32sIyyU9606 rogid:nDDSb5B6YCbq5/6qvgtnUWtP23M9606 rigid:6EMs5+B89Q89RCR/2S2BG6PhH9E false tandem tag:n-n - - - psi-mi:"MI:0658"(multidimensional protein identification technology) psi-mi:"MI:0658"(multidimensional protein identification technology) uniprotkb:P48431 uniprotkb:P52815 intact:EBI-6124081|uniprotkb:Q14537|ensembl:ENSP00000323588 intact:EBI-358272|uniprotkb:Q969U0|uniprotkb:Q9HCA2|uniprotkb:Q9UQJ3|ensembl:ENSP00000333837 psi-mi:sox2_human(display_long)|uniprotkb:SOX2(gene name)|psi-mi:SOX2(display_short) psi-mi:rm12_human(display_long)|uniprotkb:MRPL12(gene name)|psi-mi:MRPL12(display_short)|uniprotkb:RPML12(gene name synonym)|uniprotkb:5c5-2(gene name synonym)|uniprotkb:MRPL7(gene name synonym)|uniprotkb:Mitochondrial large ribosomal subunit protein bL12m(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Cox et al. (2012) pubmed:23667531|imex:IM-28599 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-26574619|imex:IM-28599-5 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_003097.1|dip:DIP-59913N|ensembl:ENSG00000181449(gene)|ensembl:ENST00000325404(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001649"(osteoblast differentiation)|go:"GO:0001654"(eye development)|go:"GO:0001714"(endodermal cell fate specification)|go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006325"(chromatin organization)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0009611"(response to wounding)|go:"GO:0009653"(anatomical structure morphogenesis)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0021781"(glial cell fate commitment)|go:"GO:0021983"(pituitary gland development)|go:"GO:0021984"(adenohypophysis development)|go:"GO:0022409"(positive regulation of cell-cell adhesion)|go:"GO:0030154"(cell differentiation)|go:"GO:0030900"(forebrain development)|go:"GO:0035019"(somatic stem cell population maintenance)|go:"GO:0035198"(miRNA binding)|go:"GO:0042246"(tissue regeneration)|go:"GO:0043281"(regulation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0043410"(positive regulation of MAPK cascade)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045165"(cell fate commitment)|go:"GO:0045597"(positive regulation of cell differentiation)|go:"GO:0045665"(negative regulation of neuron differentiation)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048839"(inner ear development)|go:"GO:0050680"(negative regulation of epithelial cell proliferation)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0070848"(response to growth factor)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:0097150"(neuronal stem cell population maintenance)|interpro:IPR009071(High mobility group box, HMG)|interpro:IPR022097|interpro:IPR032643|interpro:IPR036910|mint:P48431|rcsb pdb:1O4X|rcsb pdb:2LE4|rcsb pdb:6T7B|rcsb pdb:6T90|rcsb pdb:6WX7|rcsb pdb:6WX8|rcsb pdb:6WX9|rcsb pdb:6YOV|reactome:R-HSA-2892245|reactome:R-HSA-2892247|reactome:R-HSA-3769402|reactome:R-HSA-452723|reactome:R-HSA-6785807|reactome:R-HSA-8986944 refseq:NP_002940.2|ensembl:ENSG00000262814(gene)|ensembl:ENST00000333676(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005762"(mitochondrial large ribosomal subunit)|go:"GO:0006390"(mitochondrial transcription)|go:"GO:0006412"(translation)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|interpro:IPR000206(Ribosomal protein L7/L12)|interpro:IPR008932(Ribosomal protein L7/L12, oligomerisation)|interpro:IPR013823(Ribosomal protein L7/L12, C-terminal)|interpro:IPR014719(Ribosomal protein L7/L12, C-terminal/adaptor protein ClpS-like)|interpro:IPR036235|mint:P52815|rcsb pdb:6VLZ|rcsb pdb:6VMI|rcsb pdb:6ZM5|rcsb pdb:6ZM6|rcsb pdb:6ZS9|rcsb pdb:6ZSA|rcsb pdb:6ZSB|rcsb pdb:6ZSC|rcsb pdb:6ZSD|rcsb pdb:6ZSE|dip:DIP-50865N|rcsb pdb:6ZSG|rcsb pdb:7L08|rcsb pdb:7L20|rcsb pdb:7O9K|rcsb pdb:7O9M|rcsb pdb:7OG4|reactome:R-HSA-5368286|reactome:R-HSA-5389840|reactome:R-HSA-5419276 go:"GO:0005634"(nucleus) - - figure legend:ST2 F2A|comment:proteins identified only in our induced samples in three MudPIT analyses with the more stringent BY-adjusted significance p<0.05|dataset:Brain Disease - Neurological Diseases & Disorders|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-daoy)|taxid:9606(Homo sapiens DAOY cerebellar medulloblastoma cell line) - 2020/12/29 2020/12/29 rogid:cn8gYfKDpQc8J2ygnqny32sIyyU9606 rogid:rs6bdQ5j/8fLRbXZqqS6GgR7AzI9606 rigid:6EMs5+B89Q89RCR/2S2BG6PhH9E false tandem tag:n-n - - - psi-mi:"MI:0658"(multidimensional protein identification technology) psi-mi:"MI:0658"(multidimensional protein identification technology) uniprotkb:P48431 uniprotkb:Q03112 intact:EBI-6124081|uniprotkb:Q14537|ensembl:ENSP00000323588 intact:EBI-1384862|uniprotkb:Q16122|uniprotkb:Q99917|uniprotkb:C9JAK0|uniprotkb:Q5HYI1|uniprotkb:Q6MZS6|uniprotkb:Q8NEI5|uniprotkb:A1L4F3|uniprotkb:A8KA00|uniprotkb:B7Z8W7|uniprotkb:B7ZLQ3|uniprotkb:B7ZLQ4|uniprotkb:D3DNP7|ensembl:ENSP00000417899|intact:EBI-8475192|intact:MINT-8417693|uniprotkb:E7EQ57|uniprotkb:Q13465|uniprotkb:Q13466|uniprotkb:Q6FH90 psi-mi:sox2_human(display_long)|uniprotkb:SOX2(gene name)|psi-mi:SOX2(display_short) psi-mi:mecom_human(display_long)|uniprotkb:MECOM(gene name)|psi-mi:MECOM(display_short)|uniprotkb:EVI1(gene name synonym)|uniprotkb:Ecotropic virus integration site 1 protein homolog(gene name synonym)|uniprotkb:MDS1(gene name synonym)|uniprotkb:Myelodysplasia syndrome 1 protein(gene name synonym)|uniprotkb:Myelodysplasia syndrome-associated protein 1(gene name synonym)|uniprotkb:MDS1 and EVI1 complex locus protein(gene name synonym)|uniprotkb:PRDM3(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Cox et al. (2012) pubmed:23667531|imex:IM-28599 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-26574619|imex:IM-28599-5 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_003097.1|dip:DIP-59913N|ensembl:ENSG00000181449(gene)|ensembl:ENST00000325404(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001649"(osteoblast differentiation)|go:"GO:0001654"(eye development)|go:"GO:0001714"(endodermal cell fate specification)|go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006325"(chromatin organization)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0009611"(response to wounding)|go:"GO:0009653"(anatomical structure morphogenesis)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0021781"(glial cell fate commitment)|go:"GO:0021983"(pituitary gland development)|go:"GO:0021984"(adenohypophysis development)|go:"GO:0022409"(positive regulation of cell-cell adhesion)|go:"GO:0030154"(cell differentiation)|go:"GO:0030900"(forebrain development)|go:"GO:0035019"(somatic stem cell population maintenance)|go:"GO:0035198"(miRNA binding)|go:"GO:0042246"(tissue regeneration)|go:"GO:0043281"(regulation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0043410"(positive regulation of MAPK cascade)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045165"(cell fate commitment)|go:"GO:0045597"(positive regulation of cell differentiation)|go:"GO:0045665"(negative regulation of neuron differentiation)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048839"(inner ear development)|go:"GO:0050680"(negative regulation of epithelial cell proliferation)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0070848"(response to growth factor)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:0097150"(neuronal stem cell population maintenance)|interpro:IPR009071(High mobility group box, HMG)|interpro:IPR022097|interpro:IPR032643|interpro:IPR036910|mint:P48431|rcsb pdb:1O4X|rcsb pdb:2LE4|rcsb pdb:6T7B|rcsb pdb:6T90|rcsb pdb:6WX7|rcsb pdb:6WX8|rcsb pdb:6WX9|rcsb pdb:6YOV|reactome:R-HSA-2892245|reactome:R-HSA-2892247|reactome:R-HSA-3769402|reactome:R-HSA-452723|reactome:R-HSA-6785807|reactome:R-HSA-8986944 refseq:NP_001098547.3|refseq:NP_001098548.2|refseq:NP_001157471.1|refseq:NP_001157472.1|refseq:NP_001192123.1|refseq:NP_004982.2|refseq:NP_005232.2|ensembl:ENSG00000085276(gene)|ensembl:ENST00000494292(transcript)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006915"(apoptotic process)|go:"GO:0016607"(nuclear speck)|go:"GO:0018024"(histone-lysine N-methyltransferase activity)|go:"GO:0030154"(cell differentiation)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043069"(negative regulation of programmed cell death)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0046329"(negative regulation of JNK cascade)|go:"GO:0046872"(metal ion binding)|go:"GO:0046974"("histone methyltransferase activity (H3-K9 specific)")|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0070828"(heterochromatin organization)|go:"GO:0071425"(hematopoietic stem cell proliferation)|interpro:IPR001214(SET)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR044411|mint:Q03112|rcsb pdb:6BW3|reactome:R-HSA-3214841|reactome:R-HSA-8943724|interpro:IPR036236|refseq:XP_016861363.1|refseq:XP_016861364.1|refseq:XP_016861365.1|refseq:XP_005247278.1|refseq:XP_005247280.1|refseq:XP_005247272.1|dip:DIP-38639N|refseq:XP_005247276.1|refseq:XP_005247277.1 go:"GO:0005634"(nucleus) - - figure legend:ST2 F2A|comment:proteins identified only in our induced samples in three MudPIT analyses with the more stringent BY-adjusted significance p<0.05|dataset:Brain Disease - Neurological Diseases & Disorders|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-daoy)|taxid:9606(Homo sapiens DAOY cerebellar medulloblastoma cell line) - 2020/12/29 2020/12/29 rogid:cn8gYfKDpQc8J2ygnqny32sIyyU9606 rogid:MAlEIuVZS4+BNoy50jejv2O30WA9606 rigid:6EMs5+B89Q89RCR/2S2BG6PhH9E false tandem tag:n-n - - - psi-mi:"MI:0658"(multidimensional protein identification technology) psi-mi:"MI:0658"(multidimensional protein identification technology) uniprotkb:P48431 uniprotkb:Q9UBF1 intact:EBI-6124081|uniprotkb:Q14537|ensembl:ENSP00000323588 intact:EBI-5651487|ensembl:ENSP00000354660|uniprotkb:Q5JZ00|uniprotkb:Q96D45|uniprotkb:Q9P1M6|uniprotkb:Q9P1M7 psi-mi:sox2_human(display_long)|uniprotkb:SOX2(gene name)|psi-mi:SOX2(display_short) psi-mi:magc2_human(display_long)|uniprotkb:MAGEC2(gene name)|psi-mi:MAGEC2(display_short)|uniprotkb:HCA587(gene name synonym)|uniprotkb:MAGEE1(gene name synonym)|uniprotkb:Cancer/testis antigen 10(gene name synonym)|uniprotkb:Hepatocellular carcinoma-associated antigen 587(gene name synonym)|uniprotkb:MAGE-C2 antigen(gene name synonym)|uniprotkb:MAGE-E1 antigen(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Cox et al. (2012) pubmed:23667531|imex:IM-28599 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-26574619|imex:IM-28599-5 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_003097.1|dip:DIP-59913N|ensembl:ENSG00000181449(gene)|ensembl:ENST00000325404(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001649"(osteoblast differentiation)|go:"GO:0001654"(eye development)|go:"GO:0001714"(endodermal cell fate specification)|go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006325"(chromatin organization)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0009611"(response to wounding)|go:"GO:0009653"(anatomical structure morphogenesis)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0021781"(glial cell fate commitment)|go:"GO:0021983"(pituitary gland development)|go:"GO:0021984"(adenohypophysis development)|go:"GO:0022409"(positive regulation of cell-cell adhesion)|go:"GO:0030154"(cell differentiation)|go:"GO:0030900"(forebrain development)|go:"GO:0035019"(somatic stem cell population maintenance)|go:"GO:0035198"(miRNA binding)|go:"GO:0042246"(tissue regeneration)|go:"GO:0043281"(regulation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0043410"(positive regulation of MAPK cascade)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045165"(cell fate commitment)|go:"GO:0045597"(positive regulation of cell differentiation)|go:"GO:0045665"(negative regulation of neuron differentiation)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048839"(inner ear development)|go:"GO:0050680"(negative regulation of epithelial cell proliferation)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0070848"(response to growth factor)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:0097150"(neuronal stem cell population maintenance)|interpro:IPR009071(High mobility group box, HMG)|interpro:IPR022097|interpro:IPR032643|interpro:IPR036910|mint:P48431|rcsb pdb:1O4X|rcsb pdb:2LE4|rcsb pdb:6T7B|rcsb pdb:6T90|rcsb pdb:6WX7|rcsb pdb:6WX8|rcsb pdb:6WX9|rcsb pdb:6YOV|reactome:R-HSA-2892245|reactome:R-HSA-2892247|reactome:R-HSA-3769402|reactome:R-HSA-452723|reactome:R-HSA-6785807|reactome:R-HSA-8986944 ensembl:ENSG00000046774(gene)|ensembl:ENST00000247452(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0044257"(cellular protein catabolic process)|go:"GO:0051443"(positive regulation of ubiquitin-protein transferase activity)|interpro:IPR002190(MAGE protein)|interpro:IPR037445|interpro:IPR041898|interpro:IPR041899|mint:Q9UBF1|refseq:NP_057333.1 go:"GO:0005634"(nucleus) - - figure legend:ST2 F2A|comment:proteins identified only in our induced samples in three MudPIT analyses with the more stringent BY-adjusted significance p<0.05|dataset:Brain Disease - Neurological Diseases & Disorders|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-daoy)|taxid:9606(Homo sapiens DAOY cerebellar medulloblastoma cell line) - 2020/12/29 2020/12/29 rogid:cn8gYfKDpQc8J2ygnqny32sIyyU9606 rogid:lGcxRZfLWWLMYlSxCxYL6XtoSAs9606 rigid:6EMs5+B89Q89RCR/2S2BG6PhH9E false tandem tag:n-n - - - psi-mi:"MI:0658"(multidimensional protein identification technology) psi-mi:"MI:0658"(multidimensional protein identification technology) uniprotkb:P48431 uniprotkb:Q6PD62 intact:EBI-6124081|uniprotkb:Q14537|ensembl:ENSP00000323588 intact:EBI-1019583|uniprotkb:Q15015|uniprotkb:D3DQV8|ensembl:ENSP00000355013 psi-mi:sox2_human(display_long)|uniprotkb:SOX2(gene name)|psi-mi:SOX2(display_short) psi-mi:ctr9_human(display_long)|uniprotkb:CTR9(gene name)|psi-mi:CTR9(display_short)|uniprotkb:KIAA0155(gene name synonym)|uniprotkb:SH2BP1(gene name synonym)|uniprotkb:SH2 domain-binding protein 1(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Cox et al. (2012) pubmed:23667531|imex:IM-28599 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-26574619|imex:IM-28599-5 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_003097.1|dip:DIP-59913N|ensembl:ENSG00000181449(gene)|ensembl:ENST00000325404(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001649"(osteoblast differentiation)|go:"GO:0001654"(eye development)|go:"GO:0001714"(endodermal cell fate specification)|go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006325"(chromatin organization)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0009611"(response to wounding)|go:"GO:0009653"(anatomical structure morphogenesis)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0021781"(glial cell fate commitment)|go:"GO:0021983"(pituitary gland development)|go:"GO:0021984"(adenohypophysis development)|go:"GO:0022409"(positive regulation of cell-cell adhesion)|go:"GO:0030154"(cell differentiation)|go:"GO:0030900"(forebrain development)|go:"GO:0035019"(somatic stem cell population maintenance)|go:"GO:0035198"(miRNA binding)|go:"GO:0042246"(tissue regeneration)|go:"GO:0043281"(regulation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0043410"(positive regulation of MAPK cascade)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045165"(cell fate commitment)|go:"GO:0045597"(positive regulation of cell differentiation)|go:"GO:0045665"(negative regulation of neuron differentiation)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048839"(inner ear development)|go:"GO:0050680"(negative regulation of epithelial cell proliferation)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0070848"(response to growth factor)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:0097150"(neuronal stem cell population maintenance)|interpro:IPR009071(High mobility group box, HMG)|interpro:IPR022097|interpro:IPR032643|interpro:IPR036910|mint:P48431|rcsb pdb:1O4X|rcsb pdb:2LE4|rcsb pdb:6T7B|rcsb pdb:6T90|rcsb pdb:6WX7|rcsb pdb:6WX8|rcsb pdb:6WX9|rcsb pdb:6YOV|reactome:R-HSA-2892245|reactome:R-HSA-2892247|reactome:R-HSA-3769402|reactome:R-HSA-452723|reactome:R-HSA-6785807|reactome:R-HSA-8986944 refseq:NP_055448.1|ensembl:ENSG00000198730(gene)|ensembl:ENST00000361367(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000993"(RNA polymerase II complex binding)|go:"GO:0001711"(endodermal cell fate commitment)|go:"GO:0001826"(inner cell mass cell differentiation)|go:"GO:0001829"(trophectodermal cell differentiation)|go:"GO:0001832"(blastocyst growth)|go:"GO:0001835"(blastocyst hatching)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006368"(transcription elongation from RNA polymerase II promoter)|go:"GO:0007259"(receptor signaling pathway via JAK-STAT)|go:"GO:0010390"(histone monoubiquitination)|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0016593"(Cdc73/Paf1 complex)|go:"GO:0016607"(nuclear speck)|go:"GO:0019827"(stem cell population maintenance)|go:"GO:0033523"(histone H2B ubiquitination)|go:"GO:0035327"|go:"GO:0042169"(SH2 domain binding)|go:"GO:0045638"(negative regulation of myeloid cell differentiation)|go:"GO:0051569"(regulation of histone H3-K4 methylation)|go:"GO:0051571"(positive regulation of histone H3-K4 methylation)|go:"GO:0070102"(interleukin-6-mediated signaling pathway)|go:"GO:0071222"(cellular response to lipopolysaccharide)|go:"GO:0080182"(histone H3-K4 trimethylation)|go:"GO:1900364"(negative regulation of mRNA polyadenylation)|go:"GO:2000653"(regulation of genetic imprinting)|go:"GO:2001162"(positive regulation of histone H3-K79 methylation)|go:"GO:2001168"(positive regulation of histone H2B ubiquitination)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR019734|interpro:IPR031101|mint:Q6PD62|rcsb pdb:5ZYQ|rcsb pdb:6GMH|rcsb pdb:6TED|reactome:R-HSA-112382|reactome:R-HSA-674695|reactome:R-HSA-75955|reactome:R-HSA-8866654|dip:DIP-31693N go:"GO:0005634"(nucleus) - - figure legend:ST2 F2A|comment:proteins identified only in our induced samples in three MudPIT analyses with the more stringent BY-adjusted significance p<0.05|dataset:Brain Disease - Neurological Diseases & Disorders|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-daoy)|taxid:9606(Homo sapiens DAOY cerebellar medulloblastoma cell line) - 2020/12/29 2020/12/29 rogid:cn8gYfKDpQc8J2ygnqny32sIyyU9606 rogid:zEFAxq/VxkK8za6qsK0gcU+EU8o9606 rigid:6EMs5+B89Q89RCR/2S2BG6PhH9E false tandem tag:n-n - - - psi-mi:"MI:0658"(multidimensional protein identification technology) psi-mi:"MI:0658"(multidimensional protein identification technology) uniprotkb:P48431 uniprotkb:Q8TDN6 intact:EBI-6124081|uniprotkb:Q14537|ensembl:ENSP00000323588 intact:EBI-1052326|uniprotkb:Q3ZTT4|uniprotkb:Q8N453|uniprotkb:Q96DH1|uniprotkb:A8K0P5|ensembl:ENSP00000338862 psi-mi:sox2_human(display_long)|uniprotkb:SOX2(gene name)|psi-mi:SOX2(display_short) psi-mi:brx1_human(display_long)|uniprotkb:BRIX1(gene name)|psi-mi:BRIX1(display_short)|uniprotkb:BXDC2(gene name synonym)|uniprotkb:BRIX(gene name synonym)|uniprotkb:Brix domain-containing protein 2(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Cox et al. (2012) pubmed:23667531|imex:IM-28599 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-26574619|imex:IM-28599-5 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_003097.1|dip:DIP-59913N|ensembl:ENSG00000181449(gene)|ensembl:ENST00000325404(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001649"(osteoblast differentiation)|go:"GO:0001654"(eye development)|go:"GO:0001714"(endodermal cell fate specification)|go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006325"(chromatin organization)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0009611"(response to wounding)|go:"GO:0009653"(anatomical structure morphogenesis)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0021781"(glial cell fate commitment)|go:"GO:0021983"(pituitary gland development)|go:"GO:0021984"(adenohypophysis development)|go:"GO:0022409"(positive regulation of cell-cell adhesion)|go:"GO:0030154"(cell differentiation)|go:"GO:0030900"(forebrain development)|go:"GO:0035019"(somatic stem cell population maintenance)|go:"GO:0035198"(miRNA binding)|go:"GO:0042246"(tissue regeneration)|go:"GO:0043281"(regulation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0043410"(positive regulation of MAPK cascade)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045165"(cell fate commitment)|go:"GO:0045597"(positive regulation of cell differentiation)|go:"GO:0045665"(negative regulation of neuron differentiation)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048839"(inner ear development)|go:"GO:0050680"(negative regulation of epithelial cell proliferation)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0070848"(response to growth factor)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:0097150"(neuronal stem cell population maintenance)|interpro:IPR009071(High mobility group box, HMG)|interpro:IPR022097|interpro:IPR032643|interpro:IPR036910|mint:P48431|rcsb pdb:1O4X|rcsb pdb:2LE4|rcsb pdb:6T7B|rcsb pdb:6T90|rcsb pdb:6WX7|rcsb pdb:6WX8|rcsb pdb:6WX9|rcsb pdb:6YOV|reactome:R-HSA-2892245|reactome:R-HSA-2892247|reactome:R-HSA-3769402|reactome:R-HSA-452723|reactome:R-HSA-6785807|reactome:R-HSA-8986944 refseq:NP_060791.3|ensembl:ENSG00000113460(gene)|ensembl:ENST00000336767(transcript)|go:"GO:0000027"(ribosomal large subunit assembly)|go:"GO:0003723"(RNA binding)|go:"GO:0005694"(chromosome)|go:"GO:0005730"(nucleolus)|go:"GO:0006364"(rRNA processing)|go:"GO:0019843"(rRNA binding)|interpro:IPR007109(Brix)|interpro:IPR026532|mint:Q8TDN6 go:"GO:0005634"(nucleus) - - figure legend:ST2 F2A|comment:proteins identified only in our induced samples in three MudPIT analyses with the more stringent BY-adjusted significance p<0.05|dataset:Brain Disease - Neurological Diseases & Disorders|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-daoy)|taxid:9606(Homo sapiens DAOY cerebellar medulloblastoma cell line) - 2020/12/29 2020/12/29 rogid:cn8gYfKDpQc8J2ygnqny32sIyyU9606 rogid:Xa2UDOXgdmWyJ7qBZsdInDt9Vaw9606 rigid:6EMs5+B89Q89RCR/2S2BG6PhH9E false tandem tag:n-n - - - psi-mi:"MI:0658"(multidimensional protein identification technology) psi-mi:"MI:0658"(multidimensional protein identification technology) uniprotkb:P48431 uniprotkb:Q12899 intact:EBI-6124081|uniprotkb:Q14537|ensembl:ENSP00000323588 intact:EBI-2341136|intact:EBI-2802887|uniprotkb:A6NG96|uniprotkb:Q5SRL2|ensembl:ENSP00000331131|ensembl:ENSP00000373102|ensembl:ENSP00000379806|ensembl:ENSP00000389203|ensembl:ENSP00000390258|ensembl:ENSP00000391879|ensembl:ENSP00000392805|ensembl:ENSP00000393011|ensembl:ENSP00000394371|ensembl:ENSP00000394421|ensembl:ENSP00000395491|ensembl:ENSP00000396188|ensembl:ENSP00000398545|ensembl:ENSP00000402395|ensembl:ENSP00000406707|ensembl:ENSP00000407294|ensembl:ENSP00000407876|ensembl:ENSP00000408233|ensembl:ENSP00000409182|ensembl:ENSP00000410446|ensembl:ENSP00000414248|ensembl:ENSP00000415328|ensembl:ENSP00000415755|ensembl:ENSP00000416737 psi-mi:sox2_human(display_long)|uniprotkb:SOX2(gene name)|psi-mi:SOX2(display_short) psi-mi:tri26_human(display_long)|uniprotkb:TRIM26(gene name)|psi-mi:TRIM26(display_short)|uniprotkb:RNF95(gene name synonym)|uniprotkb:ZNF173(gene name synonym)|uniprotkb:Zinc finger protein 173(gene name synonym)|uniprotkb:Acid finger protein(gene name synonym)|uniprotkb:RING finger protein 95(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Cox et al. (2012) pubmed:23667531|imex:IM-28599 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-26574619|imex:IM-28599-5 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_003097.1|dip:DIP-59913N|ensembl:ENSG00000181449(gene)|ensembl:ENST00000325404(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001649"(osteoblast differentiation)|go:"GO:0001654"(eye development)|go:"GO:0001714"(endodermal cell fate specification)|go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006325"(chromatin organization)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0009611"(response to wounding)|go:"GO:0009653"(anatomical structure morphogenesis)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0021781"(glial cell fate commitment)|go:"GO:0021983"(pituitary gland development)|go:"GO:0021984"(adenohypophysis development)|go:"GO:0022409"(positive regulation of cell-cell adhesion)|go:"GO:0030154"(cell differentiation)|go:"GO:0030900"(forebrain development)|go:"GO:0035019"(somatic stem cell population maintenance)|go:"GO:0035198"(miRNA binding)|go:"GO:0042246"(tissue regeneration)|go:"GO:0043281"(regulation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0043410"(positive regulation of MAPK cascade)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045165"(cell fate commitment)|go:"GO:0045597"(positive regulation of cell differentiation)|go:"GO:0045665"(negative regulation of neuron differentiation)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048839"(inner ear development)|go:"GO:0050680"(negative regulation of epithelial cell proliferation)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0070848"(response to growth factor)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:0097150"(neuronal stem cell population maintenance)|interpro:IPR009071(High mobility group box, HMG)|interpro:IPR022097|interpro:IPR032643|interpro:IPR036910|mint:P48431|rcsb pdb:1O4X|rcsb pdb:2LE4|rcsb pdb:6T7B|rcsb pdb:6T90|rcsb pdb:6WX7|rcsb pdb:6WX8|rcsb pdb:6WX9|rcsb pdb:6YOV|reactome:R-HSA-2892245|reactome:R-HSA-2892247|reactome:R-HSA-3769402|reactome:R-HSA-452723|reactome:R-HSA-6785807|reactome:R-HSA-8986944 refseq:XP_006715243.1|refseq:NP_001229712.1|refseq:NP_003440.1|refseq:XP_005249431.1|refseq:XP_005249432.1|refseq:XP_005249433.1|refseq:XP_005249434.1|refseq:XP_005249435.1|dip:DIP-52853N|ensembl:ENSG00000137313(gene)|ensembl:ENSG00000226060(gene)|ensembl:ENSG00000228881(gene)|ensembl:ENSG00000230230(gene)|ensembl:ENSG00000231002(gene)|ensembl:ENSG00000231641(gene)|ensembl:ENSG00000234046(gene)|ensembl:ENSG00000234127(gene)|ensembl:ENST00000327357(transcript)|ensembl:ENST00000383607(transcript)|ensembl:ENST00000396558(transcript)|ensembl:ENST00000415923(transcript)|ensembl:ENST00000422349(transcript)|ensembl:ENST00000425523(transcript)|ensembl:ENST00000425831(transcript)|ensembl:ENST00000427535(transcript)|ensembl:ENST00000428486(transcript)|ensembl:ENST00000432326(transcript)|ensembl:ENST00000433314(transcript)|ensembl:ENST00000436219(transcript)|ensembl:ENST00000437089(transcript)|ensembl:ENST00000438384(transcript)|ensembl:ENST00000438908(transcript)|ensembl:ENST00000439094(transcript)|ensembl:ENST00000445259(transcript)|ensembl:ENST00000447711(transcript)|ensembl:ENST00000450392(transcript)|ensembl:ENST00000453195(transcript)|ensembl:ENST00000454678(transcript)|ensembl:ENST00000455000(transcript)|ensembl:ENST00000456093(transcript)|ensembl:ENST00000456770(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0008270"(zinc ion binding)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0045087"(innate immune response)|go:"GO:0046597"(negative regulation of viral entry into host cell)|go:"GO:0046872"(metal ion binding)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:1902187"|interpro:IPR000315(Zinc finger, B-box)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR001870("B302 (SPRY)-like")|interpro:IPR003877(SPla/RYanodine receptor SPRY)|interpro:IPR003879(Butyrophylin-like)|interpro:IPR006574(SPRY-associated)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR013320(Concanavalin A-like lectin/glucanase, subgroup)|interpro:IPR043136|mint:Q12899|reactome:R-HSA-877300 go:"GO:0005634"(nucleus) - - figure legend:ST2 F2A|comment:proteins identified only in our induced samples in three MudPIT analyses with the more stringent BY-adjusted significance p<0.05|dataset:Brain Disease - Neurological Diseases & Disorders|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-daoy)|taxid:9606(Homo sapiens DAOY cerebellar medulloblastoma cell line) - 2020/12/29 2020/12/29 rogid:cn8gYfKDpQc8J2ygnqny32sIyyU9606 rogid:GPu3YgJ3xR1pN/MM9IKU3unCj1A9606 rigid:6EMs5+B89Q89RCR/2S2BG6PhH9E false tandem tag:n-n - - - psi-mi:"MI:0658"(multidimensional protein identification technology) psi-mi:"MI:0658"(multidimensional protein identification technology) uniprotkb:P48431 uniprotkb:Q9UJX5 intact:EBI-6124081|uniprotkb:Q14537|ensembl:ENSP00000323588 intact:EBI-2554854|uniprotkb:E9PCR4|uniprotkb:Q6PCC6|uniprotkb:A8K8H1|uniprotkb:Q9NSH6|intact:EBI-28973066|ensembl:ENSP00000318775 psi-mi:sox2_human(display_long)|uniprotkb:SOX2(gene name)|psi-mi:SOX2(display_short) psi-mi:apc4_human(display_long)|uniprotkb:APC4(gene name synonym)|uniprotkb:Cyclosome subunit 4(gene name synonym)|uniprotkb:ANAPC4(gene name)|psi-mi:ANAPC4(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Cox et al. (2012) pubmed:23667531|imex:IM-28599 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-26574619|imex:IM-28599-5 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_003097.1|dip:DIP-59913N|ensembl:ENSG00000181449(gene)|ensembl:ENST00000325404(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001649"(osteoblast differentiation)|go:"GO:0001654"(eye development)|go:"GO:0001714"(endodermal cell fate specification)|go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006325"(chromatin organization)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0009611"(response to wounding)|go:"GO:0009653"(anatomical structure morphogenesis)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0021781"(glial cell fate commitment)|go:"GO:0021983"(pituitary gland development)|go:"GO:0021984"(adenohypophysis development)|go:"GO:0022409"(positive regulation of cell-cell adhesion)|go:"GO:0030154"(cell differentiation)|go:"GO:0030900"(forebrain development)|go:"GO:0035019"(somatic stem cell population maintenance)|go:"GO:0035198"(miRNA binding)|go:"GO:0042246"(tissue regeneration)|go:"GO:0043281"(regulation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0043410"(positive regulation of MAPK cascade)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045165"(cell fate commitment)|go:"GO:0045597"(positive regulation of cell differentiation)|go:"GO:0045665"(negative regulation of neuron differentiation)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048839"(inner ear development)|go:"GO:0050680"(negative regulation of epithelial cell proliferation)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0070848"(response to growth factor)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:0097150"(neuronal stem cell population maintenance)|interpro:IPR009071(High mobility group box, HMG)|interpro:IPR022097|interpro:IPR032643|interpro:IPR036910|mint:P48431|rcsb pdb:1O4X|rcsb pdb:2LE4|rcsb pdb:6T7B|rcsb pdb:6T90|rcsb pdb:6WX7|rcsb pdb:6WX8|rcsb pdb:6WX9|rcsb pdb:6YOV|reactome:R-HSA-2892245|reactome:R-HSA-2892247|reactome:R-HSA-3769402|reactome:R-HSA-452723|reactome:R-HSA-6785807|reactome:R-HSA-8986944 ensembl:ENSP00000318775|ensembl:ENST00000510092|ensembl:ENSP00000426654|refseq:NP_037499.2|refseq:NP_001273685.1|dip:DIP-56450N|ensembl:ENSG00000053900(gene)|ensembl:ENST00000315368(transcript)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005680"(anaphase-promoting complex)|go:"GO:0005829"(cytosol)|go:"GO:0007049"(cell cycle)|go:"GO:0019903"(protein phosphatase binding)|go:"GO:0031145"(anaphase-promoting complex-dependent catabolic process)|go:"GO:0034399"(nuclear periphery)|go:"GO:0045842"(positive regulation of mitotic metaphase/anaphase transition)|go:"GO:0051301"(cell division)|go:"GO:0070979"(protein K11-linked ubiquitination)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR017169(Anaphase-promoting complex, subunit 4)|interpro:IPR024789|interpro:IPR024790|interpro:IPR024977|interpro:IPR036322|mint:Q9UJX5|rcsb pdb:4UI9|rcsb pdb:5A31|rcsb pdb:5BPW|rcsb pdb:5G04|rcsb pdb:5G05|rcsb pdb:5KHR|rcsb pdb:5KHU|rcsb pdb:5L9T|rcsb pdb:5L9U|rcsb pdb:5LCW|rcsb pdb:6Q6G|rcsb pdb:6Q6H|rcsb pdb:6TLJ|rcsb pdb:6TM5|rcsb pdb:6TNT|reactome:R-HSA-141430|reactome:R-HSA-174048|reactome:R-HSA-174084|reactome:R-HSA-174154|reactome:R-HSA-174178|reactome:R-HSA-174184|reactome:R-HSA-176407|reactome:R-HSA-176408|reactome:R-HSA-176409|reactome:R-HSA-176412|reactome:R-HSA-179409|reactome:R-HSA-2467813|reactome:R-HSA-2559582|reactome:R-HSA-69017|reactome:R-HSA-8853884|reactome:R-HSA-9687136|reactome:R-HSA-983168 go:"GO:0005634"(nucleus) - - figure legend:ST2 F2A|comment:proteins identified only in our induced samples in three MudPIT analyses with the more stringent BY-adjusted significance p<0.05|dataset:Brain Disease - Neurological Diseases & Disorders|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-daoy)|taxid:9606(Homo sapiens DAOY cerebellar medulloblastoma cell line) - 2020/12/29 2020/12/29 rogid:cn8gYfKDpQc8J2ygnqny32sIyyU9606 rogid:c3Z2ioMzMExZK39sLFZCSaAFW9M9606 rigid:6EMs5+B89Q89RCR/2S2BG6PhH9E false tandem tag:n-n - - - psi-mi:"MI:0658"(multidimensional protein identification technology) psi-mi:"MI:0658"(multidimensional protein identification technology) uniprotkb:P48431 uniprotkb:Q6VN20 intact:EBI-6124081|uniprotkb:Q14537|ensembl:ENSP00000323588 intact:EBI-310569|intact:EBI-1056526|uniprotkb:A4FTY2|uniprotkb:Q9P264|intact:EBI-10984753|ensembl:ENSP00000316589|uniprotkb:B4DID0|uniprotkb:B4DQH9|uniprotkb:E7EW27 psi-mi:sox2_human(display_long)|uniprotkb:SOX2(gene name)|psi-mi:SOX2(display_short) psi-mi:rbp10_human(display_long)|uniprotkb:RANBP10(gene name)|psi-mi:RANBP10(display_short)|uniprotkb:KIAA1464(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Cox et al. (2012) pubmed:23667531|imex:IM-28599 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-26574619|imex:IM-28599-5 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_003097.1|dip:DIP-59913N|ensembl:ENSG00000181449(gene)|ensembl:ENST00000325404(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001649"(osteoblast differentiation)|go:"GO:0001654"(eye development)|go:"GO:0001714"(endodermal cell fate specification)|go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006325"(chromatin organization)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0009611"(response to wounding)|go:"GO:0009653"(anatomical structure morphogenesis)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0021781"(glial cell fate commitment)|go:"GO:0021983"(pituitary gland development)|go:"GO:0021984"(adenohypophysis development)|go:"GO:0022409"(positive regulation of cell-cell adhesion)|go:"GO:0030154"(cell differentiation)|go:"GO:0030900"(forebrain development)|go:"GO:0035019"(somatic stem cell population maintenance)|go:"GO:0035198"(miRNA binding)|go:"GO:0042246"(tissue regeneration)|go:"GO:0043281"(regulation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0043410"(positive regulation of MAPK cascade)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045165"(cell fate commitment)|go:"GO:0045597"(positive regulation of cell differentiation)|go:"GO:0045665"(negative regulation of neuron differentiation)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048839"(inner ear development)|go:"GO:0050680"(negative regulation of epithelial cell proliferation)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0070848"(response to growth factor)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:0097150"(neuronal stem cell population maintenance)|interpro:IPR009071(High mobility group box, HMG)|interpro:IPR022097|interpro:IPR032643|interpro:IPR036910|mint:P48431|rcsb pdb:1O4X|rcsb pdb:2LE4|rcsb pdb:6T7B|rcsb pdb:6T90|rcsb pdb:6WX7|rcsb pdb:6WX8|rcsb pdb:6WX9|rcsb pdb:6YOV|reactome:R-HSA-2892245|reactome:R-HSA-2892247|reactome:R-HSA-3769402|reactome:R-HSA-452723|reactome:R-HSA-6785807|reactome:R-HSA-8986944 refseq:NP_065901.1|refseq:NP_001307167.1|refseq:NP_001307168.1|refseq:NP_001307169.1|ensembl:ENSG00000141084(gene)|ensembl:ENST00000317506(transcript)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0007010"(cytoskeleton organization)|go:"GO:0007166"(cell surface receptor signaling pathway)|interpro:IPR001870("B302 (SPRY)-like")|interpro:IPR003877(SPla/RYanodine receptor SPRY)|interpro:IPR006594(LisH dimerisation motif)|interpro:IPR006595(CTLH, C-terminal to LisH motif)|interpro:IPR013144(CT11-RanBPM)|interpro:IPR013320(Concanavalin A-like lectin/glucanase, subgroup)|interpro:IPR024964|interpro:IPR035782|interpro:IPR043136|mint:Q6VN20|reactome:R-HSA-8851805 go:"GO:0005634"(nucleus) - - figure legend:ST2 F2A|comment:proteins identified only in our induced samples in three MudPIT analyses with the more stringent BY-adjusted significance p<0.05|dataset:Brain Disease - Neurological Diseases & Disorders|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-daoy)|taxid:9606(Homo sapiens DAOY cerebellar medulloblastoma cell line) - 2020/12/29 2020/12/29 rogid:cn8gYfKDpQc8J2ygnqny32sIyyU9606 rogid:DaNPLQf0T/+lsKrL+uhGtWXG0pI9606 rigid:6EMs5+B89Q89RCR/2S2BG6PhH9E false tandem tag:n-n - - - psi-mi:"MI:0658"(multidimensional protein identification technology) psi-mi:"MI:0658"(multidimensional protein identification technology) uniprotkb:P48431 uniprotkb:P28300 intact:EBI-6124081|uniprotkb:Q14537|ensembl:ENSP00000323588 intact:EBI-3893481|uniprotkb:B2R5Q3|uniprotkb:Q5FWF0|ensembl:ENSP00000231004 psi-mi:sox2_human(display_long)|uniprotkb:SOX2(gene name)|psi-mi:SOX2(display_short) psi-mi:lyox_human(display_long)|uniprotkb:LOX(gene name)|psi-mi:LOX(display_short)|uniprotkb:Lysyl oxidase(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Cox et al. (2012) pubmed:23667531|imex:IM-28599 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-26574619|imex:IM-28599-5 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_003097.1|dip:DIP-59913N|ensembl:ENSG00000181449(gene)|ensembl:ENST00000325404(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001649"(osteoblast differentiation)|go:"GO:0001654"(eye development)|go:"GO:0001714"(endodermal cell fate specification)|go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006325"(chromatin organization)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0009611"(response to wounding)|go:"GO:0009653"(anatomical structure morphogenesis)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0021781"(glial cell fate commitment)|go:"GO:0021983"(pituitary gland development)|go:"GO:0021984"(adenohypophysis development)|go:"GO:0022409"(positive regulation of cell-cell adhesion)|go:"GO:0030154"(cell differentiation)|go:"GO:0030900"(forebrain development)|go:"GO:0035019"(somatic stem cell population maintenance)|go:"GO:0035198"(miRNA binding)|go:"GO:0042246"(tissue regeneration)|go:"GO:0043281"(regulation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0043410"(positive regulation of MAPK cascade)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045165"(cell fate commitment)|go:"GO:0045597"(positive regulation of cell differentiation)|go:"GO:0045665"(negative regulation of neuron differentiation)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048839"(inner ear development)|go:"GO:0050680"(negative regulation of epithelial cell proliferation)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0070848"(response to growth factor)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:0097150"(neuronal stem cell population maintenance)|interpro:IPR009071(High mobility group box, HMG)|interpro:IPR022097|interpro:IPR032643|interpro:IPR036910|mint:P48431|rcsb pdb:1O4X|rcsb pdb:2LE4|rcsb pdb:6T7B|rcsb pdb:6T90|rcsb pdb:6WX7|rcsb pdb:6WX8|rcsb pdb:6WX9|rcsb pdb:6YOV|reactome:R-HSA-2892245|reactome:R-HSA-2892247|reactome:R-HSA-3769402|reactome:R-HSA-452723|reactome:R-HSA-6785807|reactome:R-HSA-8986944 refseq:NP_002308.2|dip:DIP-49007N|ensembl:ENSG00000113083(gene)|ensembl:ENST00000231004(transcript)|go:"GO:0001649"(osteoblast differentiation)|go:"GO:0001932"(regulation of protein phosphorylation)|go:"GO:0004720"(protein-lysine 6-oxidase activity)|go:"GO:0005507"(copper ion binding)|go:"GO:0005518"(collagen binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005581"(collagen trimer)|go:"GO:0005615"(extracellular space)|go:"GO:0005634"(nucleus)|go:"GO:0007507"(heart development)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0016202"(regulation of striated muscle tissue development)|go:"GO:0017015"(regulation of transforming growth factor beta receptor signaling pathway)|go:"GO:0018057"(peptidyl-lysine oxidation)|go:"GO:0030199"(collagen fibril organization)|go:"GO:0030282"(bone mineralization)|go:"GO:0030324"(lung development)|go:"GO:0031012"(extracellular matrix)|go:"GO:0035791"(platelet-derived growth factor receptor-beta signaling pathway)|go:"GO:0035905"(ascending aorta development)|go:"GO:0035906"(descending aorta development)|go:"GO:0042060"(wound healing)|go:"GO:0042493"|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0043491"(protein kinase B signaling)|go:"GO:0045652"(regulation of megakaryocyte differentiation)|go:"GO:0006464"(cellular protein modification process)|go:"GO:0048251"(elastic fiber assembly)|go:"GO:0048514"(blood vessel morphogenesis)|go:"GO:0048545"(response to steroid hormone)|go:"GO:0055001"(muscle cell development)|go:"GO:0060326"(cell chemotaxis)|go:"GO:0061448"(connective tissue development)|go:"GO:0071897"(DNA biosynthetic process)|go:"GO:1900120"(regulation of receptor binding)|go:"GO:1903010"(regulation of bone development)|go:"GO:1990869"(cellular response to chemokine)|go:"GO:2000586"(regulation of platelet-derived growth factor receptor-beta signaling pathway)|interpro:IPR001695(Lysyl oxidase)|interpro:IPR019828|mint:P28300|reactome:R-HSA-1566948|reactome:R-HSA-2243919|go:"GO:0046716"(muscle cell cellular homeostasis) go:"GO:0005634"(nucleus) - - figure legend:ST2 F2A|comment:proteins identified only in our induced samples in three MudPIT analyses with the more stringent BY-adjusted significance p<0.05|dataset:Brain Disease - Neurological Diseases & Disorders|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-daoy)|taxid:9606(Homo sapiens DAOY cerebellar medulloblastoma cell line) - 2020/12/29 2020/12/29 rogid:cn8gYfKDpQc8J2ygnqny32sIyyU9606 rogid:bDUlKQ5akDOhya4GydJ+PaLs7Fo9606 rigid:6EMs5+B89Q89RCR/2S2BG6PhH9E false tandem tag:n-n - - - psi-mi:"MI:0658"(multidimensional protein identification technology) psi-mi:"MI:0658"(multidimensional protein identification technology) uniprotkb:P48431 uniprotkb:Q9UJX4 intact:EBI-6124081|uniprotkb:Q14537|ensembl:ENSP00000323588 intact:EBI-395994|uniprotkb:Q8N4H7|uniprotkb:Q9BQD4|uniprotkb:E9PFB2|ensembl:ENSP00000261819 psi-mi:sox2_human(display_long)|uniprotkb:SOX2(gene name)|psi-mi:SOX2(display_short) psi-mi:apc5_human(display_long)|uniprotkb:ANAPC5(gene name)|psi-mi:ANAPC5(display_short)|uniprotkb:APC5(gene name synonym)|uniprotkb:Cyclosome subunit 5(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Cox et al. (2012) pubmed:23667531|imex:IM-28599 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-26574619|imex:IM-28599-5 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_003097.1|dip:DIP-59913N|ensembl:ENSG00000181449(gene)|ensembl:ENST00000325404(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001649"(osteoblast differentiation)|go:"GO:0001654"(eye development)|go:"GO:0001714"(endodermal cell fate specification)|go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006325"(chromatin organization)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0009611"(response to wounding)|go:"GO:0009653"(anatomical structure morphogenesis)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0021781"(glial cell fate commitment)|go:"GO:0021983"(pituitary gland development)|go:"GO:0021984"(adenohypophysis development)|go:"GO:0022409"(positive regulation of cell-cell adhesion)|go:"GO:0030154"(cell differentiation)|go:"GO:0030900"(forebrain development)|go:"GO:0035019"(somatic stem cell population maintenance)|go:"GO:0035198"(miRNA binding)|go:"GO:0042246"(tissue regeneration)|go:"GO:0043281"(regulation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0043410"(positive regulation of MAPK cascade)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045165"(cell fate commitment)|go:"GO:0045597"(positive regulation of cell differentiation)|go:"GO:0045665"(negative regulation of neuron differentiation)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048839"(inner ear development)|go:"GO:0050680"(negative regulation of epithelial cell proliferation)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0070848"(response to growth factor)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:0097150"(neuronal stem cell population maintenance)|interpro:IPR009071(High mobility group box, HMG)|interpro:IPR022097|interpro:IPR032643|interpro:IPR036910|mint:P48431|rcsb pdb:1O4X|rcsb pdb:2LE4|rcsb pdb:6T7B|rcsb pdb:6T90|rcsb pdb:6WX7|rcsb pdb:6WX8|rcsb pdb:6WX9|rcsb pdb:6YOV|reactome:R-HSA-2892245|reactome:R-HSA-2892247|reactome:R-HSA-3769402|reactome:R-HSA-452723|reactome:R-HSA-6785807|reactome:R-HSA-8986944 refseq:NP_057321.2|refseq:NP_001131031.1|refseq:NP_001317418.1|dip:DIP-32945N|rcsb pdb:5G04|rcsb pdb:5G05|rcsb pdb:5KHR|rcsb pdb:5KHU|rcsb pdb:5L9T|rcsb pdb:5L9U|rcsb pdb:5LCW|rcsb pdb:6Q6G|rcsb pdb:6Q6H|rcsb pdb:6TLJ|rcsb pdb:6TM5|rcsb pdb:6TNT|reactome:R-HSA-141430|reactome:R-HSA-174048|reactome:R-HSA-174084|reactome:R-HSA-174154|reactome:R-HSA-174178|reactome:R-HSA-174184|reactome:R-HSA-176407|reactome:R-HSA-176408|reactome:R-HSA-176409|reactome:R-HSA-176412|reactome:R-HSA-179409|reactome:R-HSA-2467813|reactome:R-HSA-2559582|reactome:R-HSA-69017|reactome:R-HSA-8853884|reactome:R-HSA-9687136|reactome:R-HSA-983168|ensembl:ENSG00000089053(gene)|ensembl:ENST00000261819(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005680"(anaphase-promoting complex)|go:"GO:0005819"(spindle)|go:"GO:0005829"(cytosol)|go:"GO:0007049"(cell cycle)|go:"GO:0019903"(protein phosphatase binding)|go:"GO:0031145"(anaphase-promoting complex-dependent catabolic process)|go:"GO:0045842"(positive regulation of mitotic metaphase/anaphase transition)|go:"GO:0051301"(cell division)|go:"GO:0070979"(protein K11-linked ubiquitination)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR019734|interpro:IPR026000|interpro:IPR037679|mint:Q9UJX4|rcsb pdb:4UI9|rcsb pdb:5A31 go:"GO:0005634"(nucleus) - - figure legend:ST2 F2A|comment:proteins identified only in our induced samples in three MudPIT analyses with the more stringent BY-adjusted significance p<0.05|dataset:Brain Disease - Neurological Diseases & Disorders|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-daoy)|taxid:9606(Homo sapiens DAOY cerebellar medulloblastoma cell line) - 2020/12/29 2020/12/29 rogid:cn8gYfKDpQc8J2ygnqny32sIyyU9606 rogid:Bg/ZL1IEXYdO6XblNQvxjhVX9tI9606 rigid:6EMs5+B89Q89RCR/2S2BG6PhH9E false tandem tag:n-n - - - psi-mi:"MI:0658"(multidimensional protein identification technology) psi-mi:"MI:0658"(multidimensional protein identification technology) uniprotkb:P48431 uniprotkb:P63104 intact:EBI-6124081|uniprotkb:Q14537|ensembl:ENSP00000323588 intact:EBI-347088|ensembl:ENSP00000309503|ensembl:ENSP00000379281|ensembl:ENSP00000379283|ensembl:ENSP00000379286|ensembl:ENSP00000379287|ensembl:ENSP00000379288|ensembl:ENSP00000395114|ensembl:ENSP00000398599|uniprotkb:P29213|uniprotkb:P29312|uniprotkb:Q32P43|uniprotkb:Q5XJ08|uniprotkb:Q6GPI2|uniprotkb:Q6IN74|uniprotkb:Q6NUR9|uniprotkb:Q6P3U9|uniprotkb:Q86V33|uniprotkb:A8K1N0|uniprotkb:B7Z465 psi-mi:sox2_human(display_long)|uniprotkb:SOX2(gene name)|psi-mi:SOX2(display_short) psi-mi:1433z_human(display_long)|uniprotkb:YWHAZ(gene name)|psi-mi:YWHAZ(display_short)|uniprotkb:Protein kinase C inhibitor protein 1(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Cox et al. (2012) pubmed:23667531|imex:IM-28599 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-26574619|imex:IM-28599-5 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_003097.1|dip:DIP-59913N|ensembl:ENSG00000181449(gene)|ensembl:ENST00000325404(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001649"(osteoblast differentiation)|go:"GO:0001654"(eye development)|go:"GO:0001714"(endodermal cell fate specification)|go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006325"(chromatin organization)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0009611"(response to wounding)|go:"GO:0009653"(anatomical structure morphogenesis)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0021781"(glial cell fate commitment)|go:"GO:0021983"(pituitary gland development)|go:"GO:0021984"(adenohypophysis development)|go:"GO:0022409"(positive regulation of cell-cell adhesion)|go:"GO:0030154"(cell differentiation)|go:"GO:0030900"(forebrain development)|go:"GO:0035019"(somatic stem cell population maintenance)|go:"GO:0035198"(miRNA binding)|go:"GO:0042246"(tissue regeneration)|go:"GO:0043281"(regulation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0043410"(positive regulation of MAPK cascade)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045165"(cell fate commitment)|go:"GO:0045597"(positive regulation of cell differentiation)|go:"GO:0045665"(negative regulation of neuron differentiation)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048839"(inner ear development)|go:"GO:0050680"(negative regulation of epithelial cell proliferation)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0070848"(response to growth factor)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:0097150"(neuronal stem cell population maintenance)|interpro:IPR009071(High mobility group box, HMG)|interpro:IPR022097|interpro:IPR032643|interpro:IPR036910|mint:P48431|rcsb pdb:1O4X|rcsb pdb:2LE4|rcsb pdb:6T7B|rcsb pdb:6T90|rcsb pdb:6WX7|rcsb pdb:6WX8|rcsb pdb:6WX9|rcsb pdb:6YOV|reactome:R-HSA-2892245|reactome:R-HSA-2892247|reactome:R-HSA-3769402|reactome:R-HSA-452723|reactome:R-HSA-6785807|reactome:R-HSA-8986944 ensembl:ENSG00000164924(gene)|ensembl:ENST00000353245(transcript)|ensembl:ENST00000395951(transcript)|ensembl:ENST00000395953(transcript)|ensembl:ENST00000395956(transcript)|ensembl:ENST00000395957(transcript)|ensembl:ENST00000395958(transcript)|ensembl:ENST00000419477(transcript)|ensembl:ENST00000457309(transcript)|go:"GO:0001525"(angiogenesis)|go:"GO:0003016"(respiratory system process)|go:"GO:0003723"(RNA binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005925"(focal adhesion)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0006605"(protein targeting)|go:"GO:0007165"(signal transduction)|go:"GO:0008039"(synaptic target recognition)|go:"GO:0019901"(protein kinase binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030324"(lung development)|go:"GO:0031982"(vesicle)|go:"GO:0035148"(tube formation)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0042470"(melanosome)|go:"GO:0042802"(identical protein binding)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0045296"(cadherin binding)|go:"GO:0051683"(establishment of Golgi localization)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070371"(ERK1 and ERK2 cascade)|go:"GO:0070372"(regulation of ERK1 and ERK2 cascade)|go:"GO:0072562"(blood microparticle)|go:"GO:0090128"(regulation of synapse maturation)|go:"GO:0090168"(Golgi reassembly)|go:"GO:0098686"(hippocampal mossy fiber to CA3 synapse)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0140297"(DNA-binding transcription factor binding)|interpro:IPR000308(14-3-3 protein)|interpro:IPR023409|interpro:IPR023410|interpro:IPR036815|rcsb pdb:1IB1|rcsb pdb:1QJA|rcsb pdb:1QJB|rcsb pdb:2C1J|rcsb pdb:2C1N|rcsb pdb:2O02|rcsb pdb:2WH0|rcsb pdb:3CU8|mint:P63104|rcsb pdb:3NKX|rcsb pdb:3RDH|rcsb pdb:4BG6|rcsb pdb:4FJ3|rcsb pdb:4HKC|rcsb pdb:4IHL|rcsb pdb:4N7G|rcsb pdb:4N7Y|rcsb pdb:4N84|rcsb pdb:4WRQ|rcsb pdb:4ZDR|rcsb pdb:5D2D|rcsb pdb:5D3F|rcsb pdb:5EWZ|rcsb pdb:5EXA|rcsb pdb:5JM4|rcsb pdb:5M35|rcsb pdb:5M36|rcsb pdb:5M37|rcsb pdb:5NAS|rcsb pdb:5ULO|rcsb pdb:5WXN|rcsb pdb:5XY9|rcsb pdb:6EF5|rcsb pdb:6EJL|rcsb pdb:6EWW|rcsb pdb:6F08|rcsb pdb:6F09|rcsb pdb:6FN9|rcsb pdb:5J31|rcsb pdb:6FNA|rcsb pdb:6FNB|rcsb pdb:6FNC|rcsb pdb:6Q0K|rcsb pdb:6RLZ|rcsb pdb:6U2H|rcsb pdb:6XAG|rcsb pdb:6YMO|rcsb pdb:6YO8|rcsb pdb:6ZFD|rcsb pdb:6ZFG|rcsb pdb:7D8H|rcsb pdb:7D8P|rcsb pdb:7D9V|reactome:R-HSA-111447|reactome:R-HSA-1445148|reactome:R-HSA-3769402|reactome:R-HSA-392517|reactome:R-HSA-430116|reactome:R-HSA-450604|reactome:R-HSA-512988|reactome:R-HSA-5625740|rcsb pdb:6YOS|reactome:R-HSA-5628897|reactome:R-HSA-75035|reactome:R-HSA-9013700|reactome:R-HSA-9604323|reactome:R-HSA-9614399|refseq:NP_001129171.1|refseq:NP_001129172.1|refseq:NP_001129173.1|refseq:NP_001129174.1|refseq:NP_003397.1|refseq:NP_663723.1|refseq:XP_005251118.1|refseq:XP_005251120.1|refseq:XP_016869299.1|refseq:XP_016869300.1|dip:DIP-563N go:"GO:0005634"(nucleus) - - figure legend:ST2 F2A|comment:proteins identified only in our induced samples in three MudPIT analyses with the more stringent BY-adjusted significance p<0.05|dataset:Brain Disease - Neurological Diseases & Disorders|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-daoy)|taxid:9606(Homo sapiens DAOY cerebellar medulloblastoma cell line) - 2020/12/29 2020/12/29 rogid:cn8gYfKDpQc8J2ygnqny32sIyyU9606 rogid:70ZqFn0J1A7ykybulqWg4Ll21+U9606 rigid:6EMs5+B89Q89RCR/2S2BG6PhH9E false tandem tag:n-n - - - psi-mi:"MI:0658"(multidimensional protein identification technology) psi-mi:"MI:0658"(multidimensional protein identification technology) uniprotkb:P48431 uniprotkb:Q8NHZ8 intact:EBI-6124081|uniprotkb:Q14537|ensembl:ENSP00000323588 intact:EBI-2555941|ensembl:ENSP00000363322 psi-mi:sox2_human(display_long)|uniprotkb:SOX2(gene name)|psi-mi:SOX2(display_short) psi-mi:cdc26_human(display_long)|uniprotkb:ANAPC12(gene name synonym)|uniprotkb:Anaphase-promoting complex subunit 12(gene name synonym)|uniprotkb:C9orf17(gene name synonym)|uniprotkb:Cell division cycle protein 26 homolog(gene name synonym)|uniprotkb:CDC26(gene name)|psi-mi:CDC26(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Cox et al. (2012) pubmed:23667531|imex:IM-28599 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-26574619|imex:IM-28599-5 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_003097.1|dip:DIP-59913N|ensembl:ENSG00000181449(gene)|ensembl:ENST00000325404(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001649"(osteoblast differentiation)|go:"GO:0001654"(eye development)|go:"GO:0001714"(endodermal cell fate specification)|go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006325"(chromatin organization)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0009611"(response to wounding)|go:"GO:0009653"(anatomical structure morphogenesis)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0021781"(glial cell fate commitment)|go:"GO:0021983"(pituitary gland development)|go:"GO:0021984"(adenohypophysis development)|go:"GO:0022409"(positive regulation of cell-cell adhesion)|go:"GO:0030154"(cell differentiation)|go:"GO:0030900"(forebrain development)|go:"GO:0035019"(somatic stem cell population maintenance)|go:"GO:0035198"(miRNA binding)|go:"GO:0042246"(tissue regeneration)|go:"GO:0043281"(regulation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0043410"(positive regulation of MAPK cascade)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045165"(cell fate commitment)|go:"GO:0045597"(positive regulation of cell differentiation)|go:"GO:0045665"(negative regulation of neuron differentiation)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048839"(inner ear development)|go:"GO:0050680"(negative regulation of epithelial cell proliferation)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0070848"(response to growth factor)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:0097150"(neuronal stem cell population maintenance)|interpro:IPR009071(High mobility group box, HMG)|interpro:IPR022097|interpro:IPR032643|interpro:IPR036910|mint:P48431|rcsb pdb:1O4X|rcsb pdb:2LE4|rcsb pdb:6T7B|rcsb pdb:6T90|rcsb pdb:6WX7|rcsb pdb:6WX8|rcsb pdb:6WX9|rcsb pdb:6YOV|reactome:R-HSA-2892245|reactome:R-HSA-2892247|reactome:R-HSA-3769402|reactome:R-HSA-452723|reactome:R-HSA-6785807|reactome:R-HSA-8986944 dip:DIP-48551N|refseq:NP_644815.1|ensembl:ENSG00000176386(gene)|ensembl:ENST00000374206(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005680"(anaphase-promoting complex)|go:"GO:0005829"(cytosol)|go:"GO:0007049"(cell cycle)|go:"GO:0007346"(regulation of mitotic cell cycle)|go:"GO:0030071"(regulation of mitotic metaphase/anaphase transition)|go:"GO:0031145"(anaphase-promoting complex-dependent catabolic process)|go:"GO:0051301"(cell division)|go:"GO:0070979"(protein K11-linked ubiquitination)|interpro:IPR018860|mint:Q8NHZ8|rcsb pdb:3HYM|rcsb pdb:4UI9|rcsb pdb:5A31|rcsb pdb:5G04|rcsb pdb:5G05|rcsb pdb:5KHR|rcsb pdb:5KHU|rcsb pdb:5L9T|rcsb pdb:5L9U|rcsb pdb:5LCW|rcsb pdb:6Q6G|rcsb pdb:6Q6H|rcsb pdb:6TLJ|rcsb pdb:6TM5|rcsb pdb:6TNT|reactome:R-HSA-141430|reactome:R-HSA-176407|reactome:R-HSA-176408|reactome:R-HSA-176409|reactome:R-HSA-176412|reactome:R-HSA-179409|reactome:R-HSA-2467813|reactome:R-HSA-2559582|reactome:R-HSA-174048|reactome:R-HSA-69017|reactome:R-HSA-174084|reactome:R-HSA-8853884|reactome:R-HSA-9687136|reactome:R-HSA-983168|reactome:R-HSA-174154|reactome:R-HSA-174178|reactome:R-HSA-174184|refseq:XP_016870062.1|refseq:XP_016870063.1|refseq:XP_016870064.1 go:"GO:0005634"(nucleus) - - figure legend:ST2 F2A|comment:proteins identified only in our induced samples in three MudPIT analyses with the more stringent BY-adjusted significance p<0.05|dataset:Brain Disease - Neurological Diseases & Disorders|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-daoy)|taxid:9606(Homo sapiens DAOY cerebellar medulloblastoma cell line) - 2020/12/29 2020/12/29 rogid:cn8gYfKDpQc8J2ygnqny32sIyyU9606 rogid:cEo8S5g8dgb5r54+8FFc8ZFcCB09606 rigid:6EMs5+B89Q89RCR/2S2BG6PhH9E false tandem tag:n-n - - - psi-mi:"MI:0658"(multidimensional protein identification technology) psi-mi:"MI:0658"(multidimensional protein identification technology) uniprotkb:P48431 uniprotkb:Q9H1A4 intact:EBI-6124081|uniprotkb:Q14537|ensembl:ENSP00000323588 intact:EBI-395918|uniprotkb:Q2M3H8|uniprotkb:Q9BSE6|uniprotkb:Q9H8D0|ensembl:ENSP00000339109 psi-mi:sox2_human(display_long)|uniprotkb:SOX2(gene name)|psi-mi:SOX2(display_short) psi-mi:apc1_human(display_long)|uniprotkb:ANAPC1(gene name)|psi-mi:ANAPC1(display_short)|uniprotkb:TSG24(gene name synonym)|uniprotkb:Cyclosome subunit 1(gene name synonym)|uniprotkb:Testis-specific gene 24 protein(gene name synonym)|uniprotkb:Mitotic checkpoint regulator(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Cox et al. (2012) pubmed:23667531|imex:IM-28599 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-26574619|imex:IM-28599-5 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_003097.1|dip:DIP-59913N|ensembl:ENSG00000181449(gene)|ensembl:ENST00000325404(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001649"(osteoblast differentiation)|go:"GO:0001654"(eye development)|go:"GO:0001714"(endodermal cell fate specification)|go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006325"(chromatin organization)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0009611"(response to wounding)|go:"GO:0009653"(anatomical structure morphogenesis)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0021781"(glial cell fate commitment)|go:"GO:0021983"(pituitary gland development)|go:"GO:0021984"(adenohypophysis development)|go:"GO:0022409"(positive regulation of cell-cell adhesion)|go:"GO:0030154"(cell differentiation)|go:"GO:0030900"(forebrain development)|go:"GO:0035019"(somatic stem cell population maintenance)|go:"GO:0035198"(miRNA binding)|go:"GO:0042246"(tissue regeneration)|go:"GO:0043281"(regulation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0043410"(positive regulation of MAPK cascade)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045165"(cell fate commitment)|go:"GO:0045597"(positive regulation of cell differentiation)|go:"GO:0045665"(negative regulation of neuron differentiation)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048839"(inner ear development)|go:"GO:0050680"(negative regulation of epithelial cell proliferation)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0070848"(response to growth factor)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:0097150"(neuronal stem cell population maintenance)|interpro:IPR009071(High mobility group box, HMG)|interpro:IPR022097|interpro:IPR032643|interpro:IPR036910|mint:P48431|rcsb pdb:1O4X|rcsb pdb:2LE4|rcsb pdb:6T7B|rcsb pdb:6T90|rcsb pdb:6WX7|rcsb pdb:6WX8|rcsb pdb:6WX9|rcsb pdb:6YOV|reactome:R-HSA-2892245|reactome:R-HSA-2892247|reactome:R-HSA-3769402|reactome:R-HSA-452723|reactome:R-HSA-6785807|reactome:R-HSA-8986944 refseq:NP_073153.1|reactome:R-HSA-174048|reactome:R-HSA-174084|reactome:R-HSA-174154|reactome:R-HSA-174178|reactome:R-HSA-174184|reactome:R-HSA-176407|reactome:R-HSA-176408|reactome:R-HSA-176409|reactome:R-HSA-176412|reactome:R-HSA-179409|reactome:R-HSA-2467813|reactome:R-HSA-2559582|reactome:R-HSA-69017|reactome:R-HSA-8853884|reactome:R-HSA-9687136|reactome:R-HSA-983168|ensembl:ENSG00000153107(gene)|rcsb pdb:4UI9|rcsb pdb:5A31|rcsb pdb:5G04|rcsb pdb:5G05|rcsb pdb:5KHR|rcsb pdb:5KHU|rcsb pdb:5L9T|ensembl:ENST00000341068(transcript)|go:"GO:0005654"(nucleoplasm)|rcsb pdb:5L9U|go:"GO:0005680"(anaphase-promoting complex)|rcsb pdb:5LCW|go:"GO:0005829"(cytosol)|go:"GO:0007091"(metaphase/anaphase transition of mitotic cell cycle)|go:"GO:0031145"(anaphase-promoting complex-dependent catabolic process)|go:"GO:0051301"(cell division)|rcsb pdb:5LGG|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0070979"(protein K11-linked ubiquitination)|rcsb pdb:6Q6G|rcsb pdb:6Q6H|rcsb pdb:6TLJ|rcsb pdb:6TM5|rcsb pdb:6TNT|reactome:R-HSA-141430|interpro:IPR011989(Armadillo-like helical)|interpro:IPR024990|interpro:IPR041221|mint:Q9H1A4|dip:DIP-32940N go:"GO:0005634"(nucleus) - - figure legend:ST2 F2A|comment:proteins identified only in our induced samples in three MudPIT analyses with the more stringent BY-adjusted significance p<0.05|dataset:Brain Disease - Neurological Diseases & Disorders|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-daoy)|taxid:9606(Homo sapiens DAOY cerebellar medulloblastoma cell line) - 2020/12/29 2020/12/29 rogid:cn8gYfKDpQc8J2ygnqny32sIyyU9606 rogid:GCcoaN+24WplwiaqcHwHsjyWn789606 rigid:6EMs5+B89Q89RCR/2S2BG6PhH9E false tandem tag:n-n - - - psi-mi:"MI:0658"(multidimensional protein identification technology) psi-mi:"MI:0658"(multidimensional protein identification technology) uniprotkb:P48431 uniprotkb:Q7L2J0 intact:EBI-6124081|uniprotkb:Q14537|ensembl:ENSP00000323588 intact:EBI-2371983|uniprotkb:Q9NPD4|uniprotkb:B3KP86|uniprotkb:D6W5V7|ensembl:ENSP00000308546 psi-mi:sox2_human(display_long)|uniprotkb:SOX2(gene name)|psi-mi:SOX2(display_short) psi-mi:mepce_human(display_long)|uniprotkb:MEPCE(gene name)|psi-mi:MEPCE(display_short)|uniprotkb:BCDIN3(gene name synonym)|uniprotkb:Bicoid-interacting protein 3 homolog(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Cox et al. (2012) pubmed:23667531|imex:IM-28599 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-26574619|imex:IM-28599-5 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_003097.1|dip:DIP-59913N|ensembl:ENSG00000181449(gene)|ensembl:ENST00000325404(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001649"(osteoblast differentiation)|go:"GO:0001654"(eye development)|go:"GO:0001714"(endodermal cell fate specification)|go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006325"(chromatin organization)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0009611"(response to wounding)|go:"GO:0009653"(anatomical structure morphogenesis)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0021781"(glial cell fate commitment)|go:"GO:0021983"(pituitary gland development)|go:"GO:0021984"(adenohypophysis development)|go:"GO:0022409"(positive regulation of cell-cell adhesion)|go:"GO:0030154"(cell differentiation)|go:"GO:0030900"(forebrain development)|go:"GO:0035019"(somatic stem cell population maintenance)|go:"GO:0035198"(miRNA binding)|go:"GO:0042246"(tissue regeneration)|go:"GO:0043281"(regulation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0043410"(positive regulation of MAPK cascade)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045165"(cell fate commitment)|go:"GO:0045597"(positive regulation of cell differentiation)|go:"GO:0045665"(negative regulation of neuron differentiation)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048839"(inner ear development)|go:"GO:0050680"(negative regulation of epithelial cell proliferation)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0070848"(response to growth factor)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:0097150"(neuronal stem cell population maintenance)|interpro:IPR009071(High mobility group box, HMG)|interpro:IPR022097|interpro:IPR032643|interpro:IPR036910|mint:P48431|rcsb pdb:1O4X|rcsb pdb:2LE4|rcsb pdb:6T7B|rcsb pdb:6T90|rcsb pdb:6WX7|rcsb pdb:6WX8|rcsb pdb:6WX9|rcsb pdb:6YOV|reactome:R-HSA-2892245|reactome:R-HSA-2892247|reactome:R-HSA-3769402|reactome:R-HSA-452723|reactome:R-HSA-6785807|reactome:R-HSA-8986944 refseq:XP_011514712.1|refseq:NP_001181919.1|refseq:NP_001181920.1|refseq:NP_001181921.1|refseq:NP_062552.2|ensembl:ENSG00000146834(gene)|ensembl:ENST00000310512(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0001510"(RNA methylation)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0008171"(O-methyltransferase activity)|go:"GO:0008173"(RNA methyltransferase activity)|go:"GO:0008757"(S-adenosylmethionine-dependent methyltransferase activity)|go:"GO:0016073"(snRNA metabolic process)|go:"GO:0017069"(snRNA binding)|go:"GO:0035562"(negative regulation of chromatin binding)|go:"GO:0040031"(snRNA modification)|go:"GO:0097322"(7SK snRNA binding)|go:"GO:0120259"(7SK snRNP)|go:"GO:1900087"(positive regulation of G1/S transition of mitotic cell cycle)|go:"GO:1904871"(positive regulation of protein localization to Cajal body)|go:"GO:1905382"(positive regulation of snRNA transcription by RNA polymerase II)|go:"GO:1990276"(RNA 5'-methyltransferase activity)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR010675(Bicoid-interacting 3)|interpro:IPR024160|interpro:IPR025714|interpro:IPR029063|interpro:IPR039772|mint:Q7L2J0|rcsb pdb:5UNA|rcsb pdb:6DCB|rcsb pdb:6DCC go:"GO:0005634"(nucleus) - - figure legend:ST2 F2A|comment:proteins identified only in our induced samples in three MudPIT analyses with the more stringent BY-adjusted significance p<0.05|dataset:Brain Disease - Neurological Diseases & Disorders|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-daoy)|taxid:9606(Homo sapiens DAOY cerebellar medulloblastoma cell line) - 2020/12/29 2020/12/29 rogid:cn8gYfKDpQc8J2ygnqny32sIyyU9606 rogid:VGhJoO3FD7nsJPVSBsKuKsPJzEM9606 rigid:6EMs5+B89Q89RCR/2S2BG6PhH9E false tandem tag:n-n - - - psi-mi:"MI:0658"(multidimensional protein identification technology) psi-mi:"MI:0658"(multidimensional protein identification technology) uniprotkb:P48431 uniprotkb:Q9H871 intact:EBI-6124081|uniprotkb:Q14537|ensembl:ENSP00000323588 intact:EBI-2797992|uniprotkb:Q6NTF0|uniprotkb:Q9H9H2|uniprotkb:Q9H6W5|uniprotkb:D6W5M6|ensembl:ENSP00000283632 psi-mi:sox2_human(display_long)|uniprotkb:SOX2(gene name)|psi-mi:SOX2(display_short) psi-mi:rmd5a_human(display_long)|uniprotkb:RMND5A(gene name)|psi-mi:RMND5A(display_short)|uniprotkb:P44CTLH(gene name synonym)|uniprotkb:Protein RMD5 homolog A(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Cox et al. (2012) pubmed:23667531|imex:IM-28599 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-26574619|imex:IM-28599-5 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_003097.1|dip:DIP-59913N|ensembl:ENSG00000181449(gene)|ensembl:ENST00000325404(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001649"(osteoblast differentiation)|go:"GO:0001654"(eye development)|go:"GO:0001714"(endodermal cell fate specification)|go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006325"(chromatin organization)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0009611"(response to wounding)|go:"GO:0009653"(anatomical structure morphogenesis)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0021781"(glial cell fate commitment)|go:"GO:0021983"(pituitary gland development)|go:"GO:0021984"(adenohypophysis development)|go:"GO:0022409"(positive regulation of cell-cell adhesion)|go:"GO:0030154"(cell differentiation)|go:"GO:0030900"(forebrain development)|go:"GO:0035019"(somatic stem cell population maintenance)|go:"GO:0035198"(miRNA binding)|go:"GO:0042246"(tissue regeneration)|go:"GO:0043281"(regulation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0043410"(positive regulation of MAPK cascade)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045165"(cell fate commitment)|go:"GO:0045597"(positive regulation of cell differentiation)|go:"GO:0045665"(negative regulation of neuron differentiation)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048839"(inner ear development)|go:"GO:0050680"(negative regulation of epithelial cell proliferation)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0070848"(response to growth factor)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:0097150"(neuronal stem cell population maintenance)|interpro:IPR009071(High mobility group box, HMG)|interpro:IPR022097|interpro:IPR032643|interpro:IPR036910|mint:P48431|rcsb pdb:1O4X|rcsb pdb:2LE4|rcsb pdb:6T7B|rcsb pdb:6T90|rcsb pdb:6WX7|rcsb pdb:6WX8|rcsb pdb:6WX9|rcsb pdb:6YOV|reactome:R-HSA-2892245|reactome:R-HSA-2892247|reactome:R-HSA-3769402|reactome:R-HSA-452723|reactome:R-HSA-6785807|reactome:R-HSA-8986944 refseq:NP_073617.1|ensembl:ENSG00000153561(gene)|ensembl:ENST00000283632(transcript)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0034657"(GID complex)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0046872"(metal ion binding)|go:"GO:0061630"(ubiquitin protein ligase activity)|interpro:IPR006594(LisH dimerisation motif)|interpro:IPR006595(CTLH, C-terminal to LisH motif)|interpro:IPR013144(CT11-RanBPM)|interpro:IPR024964|interpro:IPR037680|interpro:IPR044063|mint:Q9H871 go:"GO:0005634"(nucleus) - - figure legend:ST2 F2A|comment:proteins identified only in our induced samples in three MudPIT analyses with the more stringent BY-adjusted significance p<0.05|dataset:Brain Disease - Neurological Diseases & Disorders|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-daoy)|taxid:9606(Homo sapiens DAOY cerebellar medulloblastoma cell line) - 2020/12/29 2020/12/29 rogid:cn8gYfKDpQc8J2ygnqny32sIyyU9606 rogid:+wLGFpC1YJ1y6PVi15799YxByKI9606 rigid:6EMs5+B89Q89RCR/2S2BG6PhH9E false tandem tag:n-n - - - psi-mi:"MI:0658"(multidimensional protein identification technology) psi-mi:"MI:0658"(multidimensional protein identification technology) uniprotkb:P48431 uniprotkb:Q8IXM3 intact:EBI-6124081|uniprotkb:Q14537|ensembl:ENSP00000323588 intact:EBI-912501|uniprotkb:Q96Q49|ensembl:ENSP00000360498 psi-mi:sox2_human(display_long)|uniprotkb:SOX2(gene name)|psi-mi:SOX2(display_short) psi-mi:rm41_human(display_long)|uniprotkb:MRPL27(gene name synonym)|uniprotkb:39S ribosomal protein L27 homolog(gene name synonym)|uniprotkb:MRP-L27 homolog(gene name synonym)|uniprotkb:Bcl-2-interacting mitochondrial ribosomal protein L41(gene name synonym)|uniprotkb:Cell proliferation-inducing gene 3 protein(gene name synonym)|uniprotkb:MRPL41(gene name)|psi-mi:MRPL41(display_short)|uniprotkb:BMRP(gene name synonym)|uniprotkb:RPML27(gene name synonym)|uniprotkb:PIG3(orf name)|uniprotkb:Mitochondrial large ribosomal subunit protein mL41(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Cox et al. (2012) pubmed:23667531|imex:IM-28599 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-26574619|imex:IM-28599-5 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_003097.1|dip:DIP-59913N|ensembl:ENSG00000181449(gene)|ensembl:ENST00000325404(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001649"(osteoblast differentiation)|go:"GO:0001654"(eye development)|go:"GO:0001714"(endodermal cell fate specification)|go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006325"(chromatin organization)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0009611"(response to wounding)|go:"GO:0009653"(anatomical structure morphogenesis)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0021781"(glial cell fate commitment)|go:"GO:0021983"(pituitary gland development)|go:"GO:0021984"(adenohypophysis development)|go:"GO:0022409"(positive regulation of cell-cell adhesion)|go:"GO:0030154"(cell differentiation)|go:"GO:0030900"(forebrain development)|go:"GO:0035019"(somatic stem cell population maintenance)|go:"GO:0035198"(miRNA binding)|go:"GO:0042246"(tissue regeneration)|go:"GO:0043281"(regulation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0043410"(positive regulation of MAPK cascade)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045165"(cell fate commitment)|go:"GO:0045597"(positive regulation of cell differentiation)|go:"GO:0045665"(negative regulation of neuron differentiation)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048839"(inner ear development)|go:"GO:0050680"(negative regulation of epithelial cell proliferation)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0070848"(response to growth factor)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:0097150"(neuronal stem cell population maintenance)|interpro:IPR009071(High mobility group box, HMG)|interpro:IPR022097|interpro:IPR032643|interpro:IPR036910|mint:P48431|rcsb pdb:1O4X|rcsb pdb:2LE4|rcsb pdb:6T7B|rcsb pdb:6T90|rcsb pdb:6WX7|rcsb pdb:6WX8|rcsb pdb:6WX9|rcsb pdb:6YOV|reactome:R-HSA-2892245|reactome:R-HSA-2892247|reactome:R-HSA-3769402|reactome:R-HSA-452723|reactome:R-HSA-6785807|reactome:R-HSA-8986944 refseq:NP_115866.1|ensembl:ENSG00000182154(gene)|ensembl:ENST00000371443(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005762"(mitochondrial large ribosomal subunit)|go:"GO:0006412"(translation)|go:"GO:0006915"(apoptotic process)|go:"GO:0007049"(cell cycle)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR019189|mint:Q8IXM3|rcsb pdb:3J7Y|rcsb pdb:3J9M|rcsb pdb:5OOL|rcsb pdb:5OOM|rcsb pdb:6I9R|rcsb pdb:6NU2|rcsb pdb:6NU3|rcsb pdb:6VLZ|rcsb pdb:6VMI|rcsb pdb:6ZM5|rcsb pdb:6ZM6|rcsb pdb:6ZS9|rcsb pdb:6ZSA|rcsb pdb:6ZSB|rcsb pdb:6ZSC|rcsb pdb:6ZSD|rcsb pdb:6ZSE|rcsb pdb:6ZSG|rcsb pdb:7A5F|rcsb pdb:7A5G|rcsb pdb:7A5H|rcsb pdb:7A5I|rcsb pdb:7A5J|rcsb pdb:7A5K|rcsb pdb:7L08|rcsb pdb:7L20|rcsb pdb:7O9K|rcsb pdb:7O9M|rcsb pdb:7ODR|rcsb pdb:7ODS|rcsb pdb:7ODT|rcsb pdb:7OF0|rcsb pdb:7OF2|rcsb pdb:7OF3|rcsb pdb:7OF4|rcsb pdb:7OF5|rcsb pdb:7OF6|rcsb pdb:7OF7|rcsb pdb:7OG4|reactome:R-HSA-5368286|reactome:R-HSA-5389840|reactome:R-HSA-5419276 go:"GO:0005634"(nucleus) - - figure legend:ST2 F2A|comment:proteins identified only in our induced samples in three MudPIT analyses with the more stringent BY-adjusted significance p<0.05|dataset:Brain Disease - Neurological Diseases & Disorders|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-daoy)|taxid:9606(Homo sapiens DAOY cerebellar medulloblastoma cell line) - 2020/12/29 2020/12/29 rogid:cn8gYfKDpQc8J2ygnqny32sIyyU9606 rogid:1qftd9Vr6Rsymp6hgM29FeOvChA9606 rigid:6EMs5+B89Q89RCR/2S2BG6PhH9E false tandem tag:n-n - - - psi-mi:"MI:0658"(multidimensional protein identification technology) psi-mi:"MI:0658"(multidimensional protein identification technology) uniprotkb:P48431 uniprotkb:P05455 intact:EBI-6124081|uniprotkb:Q14537|ensembl:ENSP00000323588 intact:EBI-358037|ensembl:ENSP00000260956|ensembl:ENSP00000386636|uniprotkb:Q15367|uniprotkb:Q53XJ4 psi-mi:sox2_human(display_long)|uniprotkb:SOX2(gene name)|psi-mi:SOX2(display_short) psi-mi:la_human(display_long)|uniprotkb:SSB(gene name)|psi-mi:SSB(display_short)|uniprotkb:Sjoegren syndrome type B antigen(gene name synonym)|uniprotkb:La ribonucleoprotein(gene name synonym)|uniprotkb:La autoantigen(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Cox et al. (2012) pubmed:23667531|imex:IM-28599 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-26574619|imex:IM-28599-5 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_003097.1|dip:DIP-59913N|ensembl:ENSG00000181449(gene)|ensembl:ENST00000325404(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001649"(osteoblast differentiation)|go:"GO:0001654"(eye development)|go:"GO:0001714"(endodermal cell fate specification)|go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006325"(chromatin organization)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0009611"(response to wounding)|go:"GO:0009653"(anatomical structure morphogenesis)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0021781"(glial cell fate commitment)|go:"GO:0021983"(pituitary gland development)|go:"GO:0021984"(adenohypophysis development)|go:"GO:0022409"(positive regulation of cell-cell adhesion)|go:"GO:0030154"(cell differentiation)|go:"GO:0030900"(forebrain development)|go:"GO:0035019"(somatic stem cell population maintenance)|go:"GO:0035198"(miRNA binding)|go:"GO:0042246"(tissue regeneration)|go:"GO:0043281"(regulation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0043410"(positive regulation of MAPK cascade)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045165"(cell fate commitment)|go:"GO:0045597"(positive regulation of cell differentiation)|go:"GO:0045665"(negative regulation of neuron differentiation)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048839"(inner ear development)|go:"GO:0050680"(negative regulation of epithelial cell proliferation)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0070848"(response to growth factor)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:0097150"(neuronal stem cell population maintenance)|interpro:IPR009071(High mobility group box, HMG)|interpro:IPR022097|interpro:IPR032643|interpro:IPR036910|mint:P48431|rcsb pdb:1O4X|rcsb pdb:2LE4|rcsb pdb:6T7B|rcsb pdb:6T90|rcsb pdb:6WX7|rcsb pdb:6WX8|rcsb pdb:6WX9|rcsb pdb:6YOV|reactome:R-HSA-2892245|reactome:R-HSA-2892247|reactome:R-HSA-3769402|reactome:R-HSA-452723|reactome:R-HSA-6785807|reactome:R-HSA-8986944 refseq:NP_003133.1|ensembl:ENSG00000138385(gene)|ensembl:ENST00000260956(transcript)|ensembl:ENST00000409333(transcript)|go:"GO:0000049"(tRNA binding)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0001682"(tRNA 5'-leader removal)|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006400"(tRNA modification)|go:"GO:0006409"(tRNA export from nucleus)|go:"GO:0008033"(tRNA processing)|go:"GO:0008266"("poly(U) RNA binding")|go:"GO:0008334"(histone mRNA metabolic process)|go:"GO:0042780"(tRNA 3'-end processing)|go:"GO:0071045"(nuclear histone mRNA catabolic process)|refseq:NP_001281074.1|dip:DIP-29750N|go:"GO:0075522"(IRES-dependent viral translational initiation)|go:"GO:1903608"(protein localization to cytoplasmic stress granule)|go:"GO:1990825"(sequence-specific mRNA binding)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR002344(Lupus La protein)|interpro:IPR006630(RNA-binding protein Lupus La)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR014886(RNA binding motif)|interpro:IPR035979|interpro:IPR036388|interpro:IPR036390|mint:P05455|rcsb pdb:1OWX|rcsb pdb:1S79|rcsb pdb:1S7A|rcsb pdb:1YTY|rcsb pdb:1ZH5|rcsb pdb:2VOD|rcsb pdb:2VON|rcsb pdb:2VOO|rcsb pdb:2VOP|reactome:R-HSA-73980|reactome:R-HSA-749476 go:"GO:0005634"(nucleus) - - figure legend:ST2 F2A|comment:proteins identified only in our induced samples in three MudPIT analyses with the more stringent BY-adjusted significance p<0.05|dataset:Brain Disease - Neurological Diseases & Disorders|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-daoy)|taxid:9606(Homo sapiens DAOY cerebellar medulloblastoma cell line) - 2020/12/29 2020/12/29 rogid:cn8gYfKDpQc8J2ygnqny32sIyyU9606 rogid:Lgpr3jgLWGk3AZzPwjB1swJRsoQ9606 rigid:6EMs5+B89Q89RCR/2S2BG6PhH9E false tandem tag:n-n - - - psi-mi:"MI:0658"(multidimensional protein identification technology) psi-mi:"MI:0658"(multidimensional protein identification technology) uniprotkb:P48431 uniprotkb:O75487 intact:EBI-6124081|uniprotkb:Q14537|ensembl:ENSP00000323588 intact:EBI-3050469|uniprotkb:B4E2C0|ensembl:ENSP00000359864|uniprotkb:B2R6J7|uniprotkb:Q9UPD9|uniprotkb:Q96L43|uniprotkb:Q9NU08|uniprotkb:Q6ZMA6|uniprotkb:Q9UJN1 psi-mi:sox2_human(display_long)|uniprotkb:SOX2(gene name)|psi-mi:SOX2(display_short) psi-mi:gpc4_human(display_long)|uniprotkb:GPC4(gene name)|psi-mi:GPC4(display_short)|uniprotkb:K-glypican(gene name synonym)|uniprotkb:UNQ474/PRO937(orf name) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Cox et al. (2012) pubmed:23667531|imex:IM-28599 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-26574619|imex:IM-28599-5 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_003097.1|dip:DIP-59913N|ensembl:ENSG00000181449(gene)|ensembl:ENST00000325404(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001649"(osteoblast differentiation)|go:"GO:0001654"(eye development)|go:"GO:0001714"(endodermal cell fate specification)|go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006325"(chromatin organization)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0009611"(response to wounding)|go:"GO:0009653"(anatomical structure morphogenesis)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0021781"(glial cell fate commitment)|go:"GO:0021983"(pituitary gland development)|go:"GO:0021984"(adenohypophysis development)|go:"GO:0022409"(positive regulation of cell-cell adhesion)|go:"GO:0030154"(cell differentiation)|go:"GO:0030900"(forebrain development)|go:"GO:0035019"(somatic stem cell population maintenance)|go:"GO:0035198"(miRNA binding)|go:"GO:0042246"(tissue regeneration)|go:"GO:0043281"(regulation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0043410"(positive regulation of MAPK cascade)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045165"(cell fate commitment)|go:"GO:0045597"(positive regulation of cell differentiation)|go:"GO:0045665"(negative regulation of neuron differentiation)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048839"(inner ear development)|go:"GO:0050680"(negative regulation of epithelial cell proliferation)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0070848"(response to growth factor)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:0097150"(neuronal stem cell population maintenance)|interpro:IPR009071(High mobility group box, HMG)|interpro:IPR022097|interpro:IPR032643|interpro:IPR036910|mint:P48431|rcsb pdb:1O4X|rcsb pdb:2LE4|rcsb pdb:6T7B|rcsb pdb:6T90|rcsb pdb:6WX7|rcsb pdb:6WX8|rcsb pdb:6WX9|rcsb pdb:6YOV|reactome:R-HSA-2892245|reactome:R-HSA-2892247|reactome:R-HSA-3769402|reactome:R-HSA-452723|reactome:R-HSA-6785807|reactome:R-HSA-8986944 ensembl:ENSG00000076716(gene)|ensembl:ENST00000370828(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005796"(Golgi lumen)|go:"GO:0005886"(plasma membrane)|go:"GO:0009897"(external side of plasma membrane)|go:"GO:0009966"(regulation of signal transduction)|reactome:R-HSA-1971475|reactome:R-HSA-2022928|reactome:R-HSA-2024096|reactome:R-HSA-3560783|reactome:R-HSA-3560801|reactome:R-HSA-3656237|reactome:R-HSA-3656253|reactome:R-HSA-4420332|reactome:R-HSA-975634|mint:O75487|go:"GO:0009986"(cell surface)|go:"GO:0016477"(cell migration)|go:"GO:0043202"(lysosomal lumen)|go:"GO:0045202"(synapse)|go:"GO:0062023"(collagen-containing extracellular matrix)|go:"GO:0070062"(extracellular exosome)|go:"GO:0098696"(regulation of neurotransmitter receptor localization to postsynaptic specialization membrane)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099026"(anchored component of presynaptic membrane)|go:"GO:0099560"(synaptic membrane adhesion)|go:"GO:1904929"(coreceptor activity involved in Wnt signaling pathway, planar cell polarity pathway)|go:"GO:1905475"(regulation of protein localization to membrane)|go:"GO:1905606"(regulation of presynapse assembly)|interpro:IPR001863(Glypican)|interpro:IPR019803|interpro:IPR031180|go:"GO:0016055"(Wnt signaling pathway)|refseq:NP_001439.2 go:"GO:0005634"(nucleus) - - figure legend:ST2 F2A|comment:proteins identified only in our induced samples in three MudPIT analyses with the more stringent BY-adjusted significance p<0.05|dataset:Brain Disease - Neurological Diseases & Disorders|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-daoy)|taxid:9606(Homo sapiens DAOY cerebellar medulloblastoma cell line) - 2020/12/29 2020/12/29 rogid:cn8gYfKDpQc8J2ygnqny32sIyyU9606 rogid:6IC3ItqIRoNTmnS+hi/U34DlXN09606 rigid:6EMs5+B89Q89RCR/2S2BG6PhH9E false tandem tag:n-n - - - psi-mi:"MI:0658"(multidimensional protein identification technology) psi-mi:"MI:0658"(multidimensional protein identification technology) uniprotkb:P48431 uniprotkb:Q7L5Y9 intact:EBI-6124081|uniprotkb:Q14537|ensembl:ENSP00000323588 intact:EBI-10984762|ensembl:ENSP00000302830|uniprotkb:O95285|uniprotkb:Q5JB54|uniprotkb:Q6ZRD6|uniprotkb:Q9NW84|uniprotkb:Q9H9Z4|uniprotkb:Q9BQ11|uniprotkb:Q9H9V6 psi-mi:sox2_human(display_long)|uniprotkb:SOX2(gene name)|psi-mi:SOX2(display_short) psi-mi:maea_human(display_long)|uniprotkb:MAEA(gene name)|psi-mi:MAEA(display_short)|uniprotkb:Cell proliferation-inducing gene 5 protein(gene name synonym)|uniprotkb:EMP(gene name synonym)|uniprotkb:Erythroblast macrophage protein(gene name synonym)|uniprotkb:Human lung cancer oncogene 10 protein(gene name synonym)|uniprotkb:Macrophage erythroblast attacher(gene name synonym)|uniprotkb:P44EMLP(gene name synonym)|uniprotkb:HLC10(orf name)|uniprotkb:PIG5(orf name) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Cox et al. (2012) pubmed:23667531|imex:IM-28599 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-26574619|imex:IM-28599-5 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_003097.1|dip:DIP-59913N|ensembl:ENSG00000181449(gene)|ensembl:ENST00000325404(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001649"(osteoblast differentiation)|go:"GO:0001654"(eye development)|go:"GO:0001714"(endodermal cell fate specification)|go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006325"(chromatin organization)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0009611"(response to wounding)|go:"GO:0009653"(anatomical structure morphogenesis)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0021781"(glial cell fate commitment)|go:"GO:0021983"(pituitary gland development)|go:"GO:0021984"(adenohypophysis development)|go:"GO:0022409"(positive regulation of cell-cell adhesion)|go:"GO:0030154"(cell differentiation)|go:"GO:0030900"(forebrain development)|go:"GO:0035019"(somatic stem cell population maintenance)|go:"GO:0035198"(miRNA binding)|go:"GO:0042246"(tissue regeneration)|go:"GO:0043281"(regulation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0043410"(positive regulation of MAPK cascade)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045165"(cell fate commitment)|go:"GO:0045597"(positive regulation of cell differentiation)|go:"GO:0045665"(negative regulation of neuron differentiation)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048839"(inner ear development)|go:"GO:0050680"(negative regulation of epithelial cell proliferation)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0070848"(response to growth factor)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:0097150"(neuronal stem cell population maintenance)|interpro:IPR009071(High mobility group box, HMG)|interpro:IPR022097|interpro:IPR032643|interpro:IPR036910|mint:P48431|rcsb pdb:1O4X|rcsb pdb:2LE4|rcsb pdb:6T7B|rcsb pdb:6T90|rcsb pdb:6WX7|rcsb pdb:6WX8|rcsb pdb:6WX9|rcsb pdb:6YOV|reactome:R-HSA-2892245|reactome:R-HSA-2892247|reactome:R-HSA-3769402|reactome:R-HSA-452723|reactome:R-HSA-6785807|reactome:R-HSA-8986944 refseq:NP_001017405.1|refseq:NP_001284360.1|refseq:NP_005873.2|ensembl:ENSG00000090316(gene)|ensembl:ENST00000303400(transcript)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0003779"(actin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005819"(spindle)|go:"GO:0005826"(actomyosin contractile ring)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0007010"(cytoskeleton organization)|go:"GO:0007049"(cell cycle)|go:"GO:0007155"(cell adhesion)|go:"GO:0007346"(regulation of mitotic cell cycle)|go:"GO:0016363"(nuclear matrix)|go:"GO:0033033"(negative regulation of myeloid cell apoptotic process)|go:"GO:0034657"(GID complex)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0043249"(erythrocyte maturation)|go:"GO:0045721"(negative regulation of gluconeogenesis)|go:"GO:0046872"(metal ion binding)|go:"GO:0048822"(enucleate erythrocyte development)|go:"GO:0051301"(cell division)|go:"GO:0061630"(ubiquitin protein ligase activity)|interpro:IPR006594(LisH dimerisation motif)|interpro:IPR006595(CTLH, C-terminal to LisH motif)|interpro:IPR013144(CT11-RanBPM)|interpro:IPR024964|interpro:IPR027714|interpro:IPR044063|mint:Q7L5Y9 go:"GO:0005634"(nucleus) - - figure legend:ST2 F2A|comment:proteins identified only in our induced samples in three MudPIT analyses with the more stringent BY-adjusted significance p<0.05|dataset:Brain Disease - Neurological Diseases & Disorders|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-daoy)|taxid:9606(Homo sapiens DAOY cerebellar medulloblastoma cell line) - 2020/12/29 2020/12/29 rogid:cn8gYfKDpQc8J2ygnqny32sIyyU9606 rogid:8eoZgqL1bgRlGgQ3YiJDejdFWtk9606 rigid:6EMs5+B89Q89RCR/2S2BG6PhH9E false tandem tag:n-n - - - psi-mi:"MI:0658"(multidimensional protein identification technology) psi-mi:"MI:0658"(multidimensional protein identification technology) uniprotkb:P48431 uniprotkb:Q9UJX2 intact:EBI-6124081|uniprotkb:Q14537|ensembl:ENSP00000323588 intact:EBI-396137|uniprotkb:O75433|uniprotkb:Q9BS73|uniprotkb:B4E3A2|uniprotkb:B7WP05|uniprotkb:Q53FN2|uniprotkb:A8K6E5|uniprotkb:D3DQB7|ensembl:ENSP00000378350 psi-mi:sox2_human(display_long)|uniprotkb:SOX2(gene name)|psi-mi:SOX2(display_short) psi-mi:cdc23_human(display_long)|uniprotkb:CDC23(gene name)|psi-mi:CDC23(display_short)|uniprotkb:ANAPC8(gene name synonym)|uniprotkb:Anaphase-promoting complex subunit 8(gene name synonym)|uniprotkb:Cyclosome subunit 8(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Cox et al. (2012) pubmed:23667531|imex:IM-28599 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-26574619|imex:IM-28599-5 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_003097.1|dip:DIP-59913N|ensembl:ENSG00000181449(gene)|ensembl:ENST00000325404(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001649"(osteoblast differentiation)|go:"GO:0001654"(eye development)|go:"GO:0001714"(endodermal cell fate specification)|go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006325"(chromatin organization)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0009611"(response to wounding)|go:"GO:0009653"(anatomical structure morphogenesis)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0021781"(glial cell fate commitment)|go:"GO:0021983"(pituitary gland development)|go:"GO:0021984"(adenohypophysis development)|go:"GO:0022409"(positive regulation of cell-cell adhesion)|go:"GO:0030154"(cell differentiation)|go:"GO:0030900"(forebrain development)|go:"GO:0035019"(somatic stem cell population maintenance)|go:"GO:0035198"(miRNA binding)|go:"GO:0042246"(tissue regeneration)|go:"GO:0043281"(regulation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0043410"(positive regulation of MAPK cascade)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045165"(cell fate commitment)|go:"GO:0045597"(positive regulation of cell differentiation)|go:"GO:0045665"(negative regulation of neuron differentiation)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048839"(inner ear development)|go:"GO:0050680"(negative regulation of epithelial cell proliferation)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0070848"(response to growth factor)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:0097150"(neuronal stem cell population maintenance)|interpro:IPR009071(High mobility group box, HMG)|interpro:IPR022097|interpro:IPR032643|interpro:IPR036910|mint:P48431|rcsb pdb:1O4X|rcsb pdb:2LE4|rcsb pdb:6T7B|rcsb pdb:6T90|rcsb pdb:6WX7|rcsb pdb:6WX8|rcsb pdb:6WX9|rcsb pdb:6YOV|reactome:R-HSA-2892245|reactome:R-HSA-2892247|reactome:R-HSA-3769402|reactome:R-HSA-452723|reactome:R-HSA-6785807|reactome:R-HSA-8986944 refseq:NP_004652.2|dip:DIP-32959N|ensembl:ENSG00000094880(gene)|ensembl:ENST00000394886(transcript)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005680"(anaphase-promoting complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0007080"(mitotic metaphase plate congression)|go:"GO:0007091"(metaphase/anaphase transition of mitotic cell cycle)|go:"GO:0007096"(regulation of exit from mitosis)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0030071"(regulation of mitotic metaphase/anaphase transition)|go:"GO:0031145"(anaphase-promoting complex-dependent catabolic process)|go:"GO:0045842"(positive regulation of mitotic metaphase/anaphase transition)|go:"GO:0051301"(cell division)|go:"GO:0070979"(protein K11-linked ubiquitination)|interpro:IPR007192(Cdc23)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR019734|mint:Q9UJX2|rcsb pdb:4UI9|rcsb pdb:5A31|rcsb pdb:5G04|rcsb pdb:5G05|rcsb pdb:5KHR|rcsb pdb:5KHU|rcsb pdb:5L9T|rcsb pdb:5L9U|rcsb pdb:5LCW|rcsb pdb:6Q6G|rcsb pdb:6Q6H|rcsb pdb:6TLJ|rcsb pdb:6TM5|rcsb pdb:6TNT|reactome:R-HSA-141430|reactome:R-HSA-174048|reactome:R-HSA-174084|reactome:R-HSA-174154|reactome:R-HSA-174178|reactome:R-HSA-174184|reactome:R-HSA-176407|reactome:R-HSA-176408|reactome:R-HSA-176409|reactome:R-HSA-176412|reactome:R-HSA-179409|reactome:R-HSA-2467813|reactome:R-HSA-2559582|reactome:R-HSA-69017|reactome:R-HSA-8853884|reactome:R-HSA-9687136|reactome:R-HSA-983168 go:"GO:0005634"(nucleus) - - figure legend:ST2 F2A|comment:proteins identified only in our induced samples in three MudPIT analyses with the more stringent BY-adjusted significance p<0.05|dataset:Brain Disease - Neurological Diseases & Disorders|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-daoy)|taxid:9606(Homo sapiens DAOY cerebellar medulloblastoma cell line) - 2020/12/29 2020/12/29 rogid:cn8gYfKDpQc8J2ygnqny32sIyyU9606 rogid:uTZL2UHzZHLoKnio/1LcuSzZpW09606 rigid:6EMs5+B89Q89RCR/2S2BG6PhH9E false tandem tag:n-n - - - psi-mi:"MI:0658"(multidimensional protein identification technology) psi-mi:"MI:0658"(multidimensional protein identification technology) uniprotkb:P48431 uniprotkb:Q9H7D7 intact:EBI-6124081|uniprotkb:Q14537|ensembl:ENSP00000323588 intact:EBI-1046864|uniprotkb:A0MNN3|uniprotkb:Q4G100|uniprotkb:Q59EC4|uniprotkb:Q5GLZ9|uniprotkb:Q86UY4|uniprotkb:Q9H3C2|ensembl:ENSP00000504428|intact:EBI-1642504 psi-mi:sox2_human(display_long)|uniprotkb:SOX2(gene name)|psi-mi:SOX2(display_short) psi-mi:wdr26_human(display_long)|uniprotkb:CUL4- and DDB1-associated WDR protein 2(gene name synonym)|uniprotkb:Myocardial ischemic preconditioning up-regulated protein 2(gene name synonym)|uniprotkb:WDR26(gene name)|psi-mi:WDR26(display_short)|uniprotkb:CDW2(gene name synonym)|uniprotkb:MIP2(gene name synonym)|uniprotkb:PRO0852(orf name) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Cox et al. (2012) pubmed:23667531|imex:IM-28599 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-26574619|imex:IM-28599-5 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_003097.1|dip:DIP-59913N|ensembl:ENSG00000181449(gene)|ensembl:ENST00000325404(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001649"(osteoblast differentiation)|go:"GO:0001654"(eye development)|go:"GO:0001714"(endodermal cell fate specification)|go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006325"(chromatin organization)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0009611"(response to wounding)|go:"GO:0009653"(anatomical structure morphogenesis)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0021781"(glial cell fate commitment)|go:"GO:0021983"(pituitary gland development)|go:"GO:0021984"(adenohypophysis development)|go:"GO:0022409"(positive regulation of cell-cell adhesion)|go:"GO:0030154"(cell differentiation)|go:"GO:0030900"(forebrain development)|go:"GO:0035019"(somatic stem cell population maintenance)|go:"GO:0035198"(miRNA binding)|go:"GO:0042246"(tissue regeneration)|go:"GO:0043281"(regulation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0043410"(positive regulation of MAPK cascade)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045165"(cell fate commitment)|go:"GO:0045597"(positive regulation of cell differentiation)|go:"GO:0045665"(negative regulation of neuron differentiation)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048839"(inner ear development)|go:"GO:0050680"(negative regulation of epithelial cell proliferation)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0070848"(response to growth factor)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:0097150"(neuronal stem cell population maintenance)|interpro:IPR009071(High mobility group box, HMG)|interpro:IPR022097|interpro:IPR032643|interpro:IPR036910|mint:P48431|rcsb pdb:1O4X|rcsb pdb:2LE4|rcsb pdb:6T7B|rcsb pdb:6T90|rcsb pdb:6WX7|rcsb pdb:6WX8|rcsb pdb:6WX9|rcsb pdb:6YOV|reactome:R-HSA-2892245|reactome:R-HSA-2892247|reactome:R-HSA-3769402|reactome:R-HSA-452723|reactome:R-HSA-6785807|reactome:R-HSA-8986944 go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|interpro:IPR001680(WD40 repeat)|interpro:IPR006594(LisH dimerisation motif)|interpro:IPR006595(CTLH, C-terminal to LisH motif)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR036322|mint:Q9H7D7|ensembl:ENSG00000162923(gene)|ensembl:ENST00000678917(transcript)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0005634"(nucleus)|refseq:NP_001108585.2|refseq:NP_079436.4 go:"GO:0005634"(nucleus) - - figure legend:ST2 F2A|comment:proteins identified only in our induced samples in three MudPIT analyses with the more stringent BY-adjusted significance p<0.05|dataset:Brain Disease - Neurological Diseases & Disorders|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-daoy)|taxid:9606(Homo sapiens DAOY cerebellar medulloblastoma cell line) - 2020/12/29 2020/12/29 rogid:cn8gYfKDpQc8J2ygnqny32sIyyU9606 rogid:HRA6f68aldUqB1rVa7uM9srSyR49606 rigid:6EMs5+B89Q89RCR/2S2BG6PhH9E false tandem tag:n-n - - - psi-mi:"MI:0658"(multidimensional protein identification technology) psi-mi:"MI:0658"(multidimensional protein identification technology) uniprotkb:P48431 uniprotkb:Q96S59 intact:EBI-6124081|uniprotkb:Q14537|ensembl:ENSP00000323588 intact:EBI-636085|uniprotkb:A0PJA2|uniprotkb:O94764|uniprotkb:Q6P3T7|uniprotkb:Q7LBR2|uniprotkb:Q7Z7F9|ensembl:ENSP00000011619|uniprotkb:B2R8E1 psi-mi:sox2_human(display_long)|uniprotkb:SOX2(gene name)|psi-mi:SOX2(display_short) psi-mi:ranb9_human(display_long)|uniprotkb:RanBP7(gene name synonym)|uniprotkb:Ran-binding protein M(gene name synonym)|uniprotkb:BPM90(gene name synonym)|uniprotkb:BPM-L(gene name synonym)|uniprotkb:RANBP9(gene name)|psi-mi:RANBP9(display_short)|uniprotkb:RANBPM(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Cox et al. (2012) pubmed:23667531|imex:IM-28599 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-26574619|imex:IM-28599-5 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_003097.1|dip:DIP-59913N|ensembl:ENSG00000181449(gene)|ensembl:ENST00000325404(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001649"(osteoblast differentiation)|go:"GO:0001654"(eye development)|go:"GO:0001714"(endodermal cell fate specification)|go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006325"(chromatin organization)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0009611"(response to wounding)|go:"GO:0009653"(anatomical structure morphogenesis)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0021781"(glial cell fate commitment)|go:"GO:0021983"(pituitary gland development)|go:"GO:0021984"(adenohypophysis development)|go:"GO:0022409"(positive regulation of cell-cell adhesion)|go:"GO:0030154"(cell differentiation)|go:"GO:0030900"(forebrain development)|go:"GO:0035019"(somatic stem cell population maintenance)|go:"GO:0035198"(miRNA binding)|go:"GO:0042246"(tissue regeneration)|go:"GO:0043281"(regulation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0043410"(positive regulation of MAPK cascade)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045165"(cell fate commitment)|go:"GO:0045597"(positive regulation of cell differentiation)|go:"GO:0045665"(negative regulation of neuron differentiation)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048839"(inner ear development)|go:"GO:0050680"(negative regulation of epithelial cell proliferation)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0070848"(response to growth factor)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:0097150"(neuronal stem cell population maintenance)|interpro:IPR009071(High mobility group box, HMG)|interpro:IPR022097|interpro:IPR032643|interpro:IPR036910|mint:P48431|rcsb pdb:1O4X|rcsb pdb:2LE4|rcsb pdb:6T7B|rcsb pdb:6T90|rcsb pdb:6WX7|rcsb pdb:6WX8|rcsb pdb:6WX9|rcsb pdb:6YOV|reactome:R-HSA-2892245|reactome:R-HSA-2892247|reactome:R-HSA-3769402|reactome:R-HSA-452723|reactome:R-HSA-6785807|reactome:R-HSA-8986944 refseq:NP_005484.2|ensembl:ENSG00000010017(gene)|ensembl:ENST00000011619(transcript)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005875"(microtubule associated complex)|go:"GO:0005886"(plasma membrane)|go:"GO:0007010"(cytoskeleton organization)|go:"GO:0007020"(microtubule nucleation)|go:"GO:0007166"(cell surface receptor signaling pathway)|go:"GO:0016604"(nuclear body)|go:"GO:0019899"(enzyme binding)|go:"GO:0031267"(small GTPase binding)|go:"GO:0065003"(protein-containing complex assembly)|go:"GO:0070373"(negative regulation of ERK1 and ERK2 cascade)|interpro:IPR001870("B302 (SPRY)-like")|interpro:IPR003877(SPla/RYanodine receptor SPRY)|interpro:IPR006594(LisH dimerisation motif)|interpro:IPR006595(CTLH, C-terminal to LisH motif)|interpro:IPR013144(CT11-RanBPM)|interpro:IPR013320(Concanavalin A-like lectin/glucanase, subgroup)|interpro:IPR024964|interpro:IPR035782|interpro:IPR043136|mint:Q96S59|rcsb pdb:5JI7|rcsb pdb:5JI9|rcsb pdb:5JIU|rcsb pdb:7NSC|reactome:R-HSA-373760|reactome:R-HSA-5673001|go:"GO:1902993"(positive regulation of amyloid precursor protein catabolic process)|reactome:R-HSA-8851805|refseq:XP_006715008.1 go:"GO:0005634"(nucleus) - - figure legend:ST2 F2A|comment:proteins identified only in our induced samples in three MudPIT analyses with the more stringent BY-adjusted significance p<0.05|dataset:Brain Disease - Neurological Diseases & Disorders|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-daoy)|taxid:9606(Homo sapiens DAOY cerebellar medulloblastoma cell line) - 2020/12/29 2020/12/29 rogid:cn8gYfKDpQc8J2ygnqny32sIyyU9606 rogid:7jybZidQAgnkobKmGJhZ9xsEeH09606 rigid:6EMs5+B89Q89RCR/2S2BG6PhH9E false tandem tag:n-n - - - psi-mi:"MI:0658"(multidimensional protein identification technology) psi-mi:"MI:0658"(multidimensional protein identification technology) uniprotkb:P48431 uniprotkb:P62312 intact:EBI-6124081|uniprotkb:Q14537|ensembl:ENSP00000323588 intact:EBI-373310|uniprotkb:Q9Y4Y8|uniprotkb:Q4W5J5|ensembl:ENSP00000296581|ensembl:ENSP00000420929|ensembl:ENSP00000422392|ensembl:ENSP00000427036|ensembl:ENSP00000497311 psi-mi:sox2_human(display_long)|uniprotkb:SOX2(gene name)|psi-mi:SOX2(display_short) psi-mi:lsm6_human(display_long)|uniprotkb:LSM6(gene name)|psi-mi:LSM6(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Cox et al. (2012) pubmed:23667531|imex:IM-28599 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-26574619|imex:IM-28599-5 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_003097.1|dip:DIP-59913N|ensembl:ENSG00000181449(gene)|ensembl:ENST00000325404(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001649"(osteoblast differentiation)|go:"GO:0001654"(eye development)|go:"GO:0001714"(endodermal cell fate specification)|go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006325"(chromatin organization)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0009611"(response to wounding)|go:"GO:0009653"(anatomical structure morphogenesis)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0021781"(glial cell fate commitment)|go:"GO:0021983"(pituitary gland development)|go:"GO:0021984"(adenohypophysis development)|go:"GO:0022409"(positive regulation of cell-cell adhesion)|go:"GO:0030154"(cell differentiation)|go:"GO:0030900"(forebrain development)|go:"GO:0035019"(somatic stem cell population maintenance)|go:"GO:0035198"(miRNA binding)|go:"GO:0042246"(tissue regeneration)|go:"GO:0043281"(regulation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0043410"(positive regulation of MAPK cascade)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045165"(cell fate commitment)|go:"GO:0045597"(positive regulation of cell differentiation)|go:"GO:0045665"(negative regulation of neuron differentiation)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048839"(inner ear development)|go:"GO:0050680"(negative regulation of epithelial cell proliferation)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0070848"(response to growth factor)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:0097150"(neuronal stem cell population maintenance)|interpro:IPR009071(High mobility group box, HMG)|interpro:IPR022097|interpro:IPR032643|interpro:IPR036910|mint:P48431|rcsb pdb:1O4X|rcsb pdb:2LE4|rcsb pdb:6T7B|rcsb pdb:6T90|rcsb pdb:6WX7|rcsb pdb:6WX8|rcsb pdb:6WX9|rcsb pdb:6YOV|reactome:R-HSA-2892245|reactome:R-HSA-2892247|reactome:R-HSA-3769402|reactome:R-HSA-452723|reactome:R-HSA-6785807|reactome:R-HSA-8986944 refseq:NP_009011.1|ensembl:ENSG00000164167(gene)|ensembl:ENST00000296581(transcript)|ensembl:ENST00000502781(transcript)|ensembl:ENST00000504181(transcript)|ensembl:ENST00000515311(transcript)|ensembl:ENST00000649747(transcript)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0000932"(P-body)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005688"(U6 snRNP)|go:"GO:0005730"(nucleolus)|go:"GO:0005732"("sno(s)RNA-containing ribonucleoprotein complex")|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006402"(mRNA catabolic process)|go:"GO:0008033"(tRNA processing)|go:"GO:0008380"(RNA splicing)|go:"GO:0030490"(maturation of SSU-rRNA)|go:"GO:0030532"(small nuclear ribonucleoprotein complex)|go:"GO:0046540"(U4/U6 x U5 tri-snRNP complex)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0071005"(U2-type precatalytic spliceosome)|go:"GO:0120115"(Lsm2-8 complex)|interpro:IPR001163(Like-Sm ribonucleoprotein, core)|interpro:IPR010920(Like-Sm ribonucleoprotein-related, core)|interpro:IPR016487(Small nuclear ribonucleoprotein SmF)|mint:P62312|rcsb pdb:3JCR|rcsb pdb:5O9Z|rcsb pdb:6AH0|rcsb pdb:6AHD|rcsb pdb:6QW6|rcsb pdb:6QX9|rcsb pdb:7ABG|reactome:R-HSA-430039|reactome:R-HSA-72163|refseq:XP_016863161.1|refseq:XP_016863162.1|dip:DIP-31128N go:"GO:0005634"(nucleus) - - figure legend:ST2 F2A|comment:proteins identified only in our induced samples in three MudPIT analyses with the more stringent BY-adjusted significance p<0.05|dataset:Brain Disease - Neurological Diseases & Disorders|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-daoy)|taxid:9606(Homo sapiens DAOY cerebellar medulloblastoma cell line) - 2020/12/29 2020/12/29 rogid:cn8gYfKDpQc8J2ygnqny32sIyyU9606 rogid:knWeW+soIyeLSg0Xbe79er748hE9606 rigid:6EMs5+B89Q89RCR/2S2BG6PhH9E false tandem tag:n-n - - - psi-mi:"MI:0658"(multidimensional protein identification technology) psi-mi:"MI:0658"(multidimensional protein identification technology) uniprotkb:P48431 uniprotkb:Q9Y580 intact:EBI-6124081|uniprotkb:Q14537|ensembl:ENSP00000323588 intact:EBI-746903|uniprotkb:Q9NUT4|uniprotkb:B2R6K8|ensembl:ENSP00000439918 psi-mi:sox2_human(display_long)|uniprotkb:SOX2(gene name)|psi-mi:SOX2(display_short) psi-mi:rbm7_human(display_long)|uniprotkb:RNA-binding motif protein 7(gene name synonym)|uniprotkb:RBM7(gene name)|psi-mi:RBM7(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Cox et al. (2012) pubmed:23667531|imex:IM-28599 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-26574619|imex:IM-28599-5 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_003097.1|dip:DIP-59913N|ensembl:ENSG00000181449(gene)|ensembl:ENST00000325404(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001649"(osteoblast differentiation)|go:"GO:0001654"(eye development)|go:"GO:0001714"(endodermal cell fate specification)|go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006325"(chromatin organization)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0009611"(response to wounding)|go:"GO:0009653"(anatomical structure morphogenesis)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0021781"(glial cell fate commitment)|go:"GO:0021983"(pituitary gland development)|go:"GO:0021984"(adenohypophysis development)|go:"GO:0022409"(positive regulation of cell-cell adhesion)|go:"GO:0030154"(cell differentiation)|go:"GO:0030900"(forebrain development)|go:"GO:0035019"(somatic stem cell population maintenance)|go:"GO:0035198"(miRNA binding)|go:"GO:0042246"(tissue regeneration)|go:"GO:0043281"(regulation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0043410"(positive regulation of MAPK cascade)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045165"(cell fate commitment)|go:"GO:0045597"(positive regulation of cell differentiation)|go:"GO:0045665"(negative regulation of neuron differentiation)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048839"(inner ear development)|go:"GO:0050680"(negative regulation of epithelial cell proliferation)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0070848"(response to growth factor)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:0097150"(neuronal stem cell population maintenance)|interpro:IPR009071(High mobility group box, HMG)|interpro:IPR022097|interpro:IPR032643|interpro:IPR036910|mint:P48431|rcsb pdb:1O4X|rcsb pdb:2LE4|rcsb pdb:6T7B|rcsb pdb:6T90|rcsb pdb:6WX7|rcsb pdb:6WX8|rcsb pdb:6WX9|rcsb pdb:6YOV|reactome:R-HSA-2892245|reactome:R-HSA-2892247|reactome:R-HSA-3769402|reactome:R-HSA-452723|reactome:R-HSA-6785807|reactome:R-HSA-8986944 refseq:NP_001272974.1|refseq:NP_001272975.1|refseq:NP_001272976.1|refseq:NP_001272977.1|refseq:NP_057174.1|ensembl:ENSG00000076053(gene)|ensembl:ENST00000540163(transcript)|go:"GO:0000381"(regulation of alternative mRNA splicing, via spliceosome)|go:"GO:0003723"(RNA binding)|go:"GO:0003727"(single-stranded RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0016076"(snRNA catabolic process)|go:"GO:0017069"(snRNA binding)|go:"GO:0051321"(meiotic cell cycle)|go:"GO:0071889"(14-3-3 protein binding)|go:"GO:0097157"(pre-mRNA intronic binding)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR034500|interpro:IPR035979|mint:Q9Y580|rcsb pdb:2M8H|rcsb pdb:5IQQ|rcsb pdb:5LXR|rcsb pdb:5LXY|dip:DIP-48833N go:"GO:0005634"(nucleus) - - figure legend:ST2 F2A|comment:proteins identified only in our induced samples in three MudPIT analyses with the more stringent BY-adjusted significance p<0.05|dataset:Brain Disease - Neurological Diseases & Disorders|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-daoy)|taxid:9606(Homo sapiens DAOY cerebellar medulloblastoma cell line) - 2020/12/29 2020/12/29 rogid:cn8gYfKDpQc8J2ygnqny32sIyyU9606 rogid:d39RjBQTHAVQlOsmrxMX0NCR8CU9606 rigid:6EMs5+B89Q89RCR/2S2BG6PhH9E false tandem tag:n-n - - - psi-mi:"MI:0658"(multidimensional protein identification technology) psi-mi:"MI:0658"(multidimensional protein identification technology) uniprotkb:P48431 uniprotkb:Q6NZY4 intact:EBI-6124081|uniprotkb:Q14537|ensembl:ENSP00000323588 intact:EBI-1263058|uniprotkb:Q7L2P6|uniprotkb:Q8N2K5|uniprotkb:Q96SK7|uniprotkb:Q9NSS2|uniprotkb:Q9NSS3|ensembl:ENSP00000488055|ensembl:ENSP00000500728 psi-mi:sox2_human(display_long)|uniprotkb:SOX2(gene name)|psi-mi:SOX2(display_short) psi-mi:zchc8_human(display_long)|uniprotkb:ZCCHC8(gene name)|psi-mi:ZCCHC8(display_short)|uniprotkb:TRAMP-like complex RNA-binding factor ZCCHC8(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Cox et al. (2012) pubmed:23667531|imex:IM-28599 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-26574619|imex:IM-28599-5 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_003097.1|dip:DIP-59913N|ensembl:ENSG00000181449(gene)|ensembl:ENST00000325404(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001649"(osteoblast differentiation)|go:"GO:0001654"(eye development)|go:"GO:0001714"(endodermal cell fate specification)|go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006325"(chromatin organization)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0009611"(response to wounding)|go:"GO:0009653"(anatomical structure morphogenesis)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0021781"(glial cell fate commitment)|go:"GO:0021983"(pituitary gland development)|go:"GO:0021984"(adenohypophysis development)|go:"GO:0022409"(positive regulation of cell-cell adhesion)|go:"GO:0030154"(cell differentiation)|go:"GO:0030900"(forebrain development)|go:"GO:0035019"(somatic stem cell population maintenance)|go:"GO:0035198"(miRNA binding)|go:"GO:0042246"(tissue regeneration)|go:"GO:0043281"(regulation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0043410"(positive regulation of MAPK cascade)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045165"(cell fate commitment)|go:"GO:0045597"(positive regulation of cell differentiation)|go:"GO:0045665"(negative regulation of neuron differentiation)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048839"(inner ear development)|go:"GO:0050680"(negative regulation of epithelial cell proliferation)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0070848"(response to growth factor)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:0097150"(neuronal stem cell population maintenance)|interpro:IPR009071(High mobility group box, HMG)|interpro:IPR022097|interpro:IPR032643|interpro:IPR036910|mint:P48431|rcsb pdb:1O4X|rcsb pdb:2LE4|rcsb pdb:6T7B|rcsb pdb:6T90|rcsb pdb:6WX7|rcsb pdb:6WX8|rcsb pdb:6WX9|rcsb pdb:6YOV|reactome:R-HSA-2892245|reactome:R-HSA-2892247|reactome:R-HSA-3769402|reactome:R-HSA-452723|reactome:R-HSA-6785807|reactome:R-HSA-8986944 refseq:NP_060082.2|ensembl:ENSG00000033030(gene)|ensembl:ENST00000633063(transcript)|ensembl:ENST00000672018(transcript)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0008270"(zinc ion binding)|go:"GO:0016076"(snRNA catabolic process)|go:"GO:0016604"(nuclear body)|go:"GO:0031499"(TRAMP complex)|go:"GO:0034470"(ncRNA processing)|go:"GO:0071013"(catalytic step 2 spliceosome)|interpro:IPR001878(Zinc finger, CCHC-type)|interpro:IPR006568(PSP, proline-rich)|mint:Q6NZY4|rcsb pdb:5LXR|rcsb pdb:5LXY|rcsb pdb:6C90 go:"GO:0005634"(nucleus) - - figure legend:ST2 F2A|comment:proteins identified only in our induced samples in three MudPIT analyses with the more stringent BY-adjusted significance p<0.05|dataset:Brain Disease - Neurological Diseases & Disorders|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-daoy)|taxid:9606(Homo sapiens DAOY cerebellar medulloblastoma cell line) - 2020/12/29 2020/12/29 rogid:cn8gYfKDpQc8J2ygnqny32sIyyU9606 rogid:dtjoaLAUgEGavPmqaJLPnLPHLP49606 rigid:6EMs5+B89Q89RCR/2S2BG6PhH9E false tandem tag:n-n - - - psi-mi:"MI:0658"(multidimensional protein identification technology) psi-mi:"MI:0658"(multidimensional protein identification technology) uniprotkb:P48431 uniprotkb:Q9BTT0 intact:EBI-6124081|uniprotkb:Q14537|ensembl:ENSP00000323588 intact:EBI-2685059|uniprotkb:Q5TB18|uniprotkb:Q8N1S4|uniprotkb:Q8WWW9|uniprotkb:B4E0I6|uniprotkb:E9PEA6|uniprotkb:Q5TB20|ensembl:ENSP00000463154 psi-mi:sox2_human(display_long)|uniprotkb:SOX2(gene name)|psi-mi:SOX2(display_short) psi-mi:an32e_human(display_long)|uniprotkb:LANP-like protein(gene name synonym)|uniprotkb:ANP32E(gene name)|psi-mi:ANP32E(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Cox et al. (2012) pubmed:23667531|imex:IM-28599 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-26574619|imex:IM-28599-5 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_003097.1|dip:DIP-59913N|ensembl:ENSG00000181449(gene)|ensembl:ENST00000325404(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001649"(osteoblast differentiation)|go:"GO:0001654"(eye development)|go:"GO:0001714"(endodermal cell fate specification)|go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006325"(chromatin organization)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0009611"(response to wounding)|go:"GO:0009653"(anatomical structure morphogenesis)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0021781"(glial cell fate commitment)|go:"GO:0021983"(pituitary gland development)|go:"GO:0021984"(adenohypophysis development)|go:"GO:0022409"(positive regulation of cell-cell adhesion)|go:"GO:0030154"(cell differentiation)|go:"GO:0030900"(forebrain development)|go:"GO:0035019"(somatic stem cell population maintenance)|go:"GO:0035198"(miRNA binding)|go:"GO:0042246"(tissue regeneration)|go:"GO:0043281"(regulation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0043410"(positive regulation of MAPK cascade)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045165"(cell fate commitment)|go:"GO:0045597"(positive regulation of cell differentiation)|go:"GO:0045665"(negative regulation of neuron differentiation)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048839"(inner ear development)|go:"GO:0050680"(negative regulation of epithelial cell proliferation)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0070848"(response to growth factor)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:0097150"(neuronal stem cell population maintenance)|interpro:IPR009071(High mobility group box, HMG)|interpro:IPR022097|interpro:IPR032643|interpro:IPR036910|mint:P48431|rcsb pdb:1O4X|rcsb pdb:2LE4|rcsb pdb:6T7B|rcsb pdb:6T90|rcsb pdb:6WX7|rcsb pdb:6WX8|rcsb pdb:6WX9|rcsb pdb:6YOV|reactome:R-HSA-2892245|reactome:R-HSA-2892247|reactome:R-HSA-3769402|reactome:R-HSA-452723|reactome:R-HSA-6785807|reactome:R-HSA-8986944 refseq:NP_001129950.1|refseq:NP_001129951.1|refseq:NP_112182.1|refseq:NP_001267488.1|refseq:NP_001267489.1|ensembl:ENSG00000143401(gene)|ensembl:ENST00000583931(transcript)|go:"GO:0000812"(Swr1 complex)|go:"GO:0005634"(nucleus)|go:"GO:0019212"(phosphatase inhibitor activity)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0042393"(histone binding)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0043486"(histone exchange)|interpro:IPR001611(Leucine-rich repeat)|interpro:IPR032675|mint:Q9BTT0|rcsb pdb:4CAY|rcsb pdb:4NFT go:"GO:0005634"(nucleus) - - figure legend:ST2 F2A|comment:proteins identified only in our induced samples in three MudPIT analyses with the more stringent BY-adjusted significance p<0.05|dataset:Brain Disease - Neurological Diseases & Disorders|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-daoy)|taxid:9606(Homo sapiens DAOY cerebellar medulloblastoma cell line) - 2020/12/29 2020/12/29 rogid:cn8gYfKDpQc8J2ygnqny32sIyyU9606 rogid:byeFwwxqINXwewx0Gx/QXSyes8g9606 rigid:6EMs5+B89Q89RCR/2S2BG6PhH9E false tandem tag:n-n - - - psi-mi:"MI:0658"(multidimensional protein identification technology) psi-mi:"MI:0658"(multidimensional protein identification technology) uniprotkb:P48431 uniprotkb:Q8NFC6 intact:EBI-6124081|uniprotkb:Q14537|ensembl:ENSP00000323588 intact:EBI-2654318|uniprotkb:Q9NTD6|uniprotkb:Q96AL1|uniprotkb:Q9H6G0|uniprotkb:Q6P0M8|uniprotkb:Q9P2L9|ensembl:ENSP00000040738 psi-mi:sox2_human(display_long)|uniprotkb:SOX2(gene name)|psi-mi:SOX2(display_short) psi-mi:bd1l1_human(display_long)|uniprotkb:BOD1L1(gene name)|psi-mi:BOD1L1(display_short)|uniprotkb:BOD1L(gene name synonym)|uniprotkb:FAM44A(gene name synonym)|uniprotkb:KIAA1327(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Cox et al. (2012) pubmed:23667531|imex:IM-28599 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-26574619|imex:IM-28599-5 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_003097.1|dip:DIP-59913N|ensembl:ENSG00000181449(gene)|ensembl:ENST00000325404(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001649"(osteoblast differentiation)|go:"GO:0001654"(eye development)|go:"GO:0001714"(endodermal cell fate specification)|go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006325"(chromatin organization)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0009611"(response to wounding)|go:"GO:0009653"(anatomical structure morphogenesis)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0021781"(glial cell fate commitment)|go:"GO:0021983"(pituitary gland development)|go:"GO:0021984"(adenohypophysis development)|go:"GO:0022409"(positive regulation of cell-cell adhesion)|go:"GO:0030154"(cell differentiation)|go:"GO:0030900"(forebrain development)|go:"GO:0035019"(somatic stem cell population maintenance)|go:"GO:0035198"(miRNA binding)|go:"GO:0042246"(tissue regeneration)|go:"GO:0043281"(regulation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0043410"(positive regulation of MAPK cascade)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045165"(cell fate commitment)|go:"GO:0045597"(positive regulation of cell differentiation)|go:"GO:0045665"(negative regulation of neuron differentiation)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048839"(inner ear development)|go:"GO:0050680"(negative regulation of epithelial cell proliferation)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0070848"(response to growth factor)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:0097150"(neuronal stem cell population maintenance)|interpro:IPR009071(High mobility group box, HMG)|interpro:IPR022097|interpro:IPR032643|interpro:IPR036910|mint:P48431|rcsb pdb:1O4X|rcsb pdb:2LE4|rcsb pdb:6T7B|rcsb pdb:6T90|rcsb pdb:6WX7|rcsb pdb:6WX8|rcsb pdb:6WX9|rcsb pdb:6YOV|reactome:R-HSA-2892245|reactome:R-HSA-2892247|reactome:R-HSA-3769402|reactome:R-HSA-452723|reactome:R-HSA-6785807|reactome:R-HSA-8986944 refseq:NP_683692.2|ensembl:ENSG00000038219(gene)|ensembl:ENST00000040738(transcript)|go:"GO:0000922"(spindle pole)|go:"GO:0000940"(outer kinetochore)|go:"GO:0004864"(protein phosphatase inhibitor activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005876"(spindle microtubule)|go:"GO:0006281"(DNA repair)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0031297"(replication fork processing)|go:"GO:0032515"(negative regulation of phosphoprotein phosphatase activity)|go:"GO:0051721"(protein phosphatase 2A binding)|interpro:IPR043244|mint:Q8NFC6 go:"GO:0005634"(nucleus) - - figure legend:ST2 F2A|comment:proteins identified only in our induced samples in three MudPIT analyses with the more stringent BY-adjusted significance p<0.05|dataset:Brain Disease - Neurological Diseases & Disorders|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-daoy)|taxid:9606(Homo sapiens DAOY cerebellar medulloblastoma cell line) - 2020/12/29 2020/12/29 rogid:cn8gYfKDpQc8J2ygnqny32sIyyU9606 rogid:/sFfw7CP8rOZG3hZNsT0npwIZIQ9606 rigid:6EMs5+B89Q89RCR/2S2BG6PhH9E false tandem tag:n-n - - - psi-mi:"MI:0658"(multidimensional protein identification technology) psi-mi:"MI:0658"(multidimensional protein identification technology) uniprotkb:P48431 uniprotkb:Q96PN7 intact:EBI-6124081|uniprotkb:Q14537|ensembl:ENSP00000323588 intact:EBI-3505166|uniprotkb:Q05GC6|uniprotkb:Q7Z6T2|uniprotkb:Q7Z6T3|uniprotkb:Q9NQ72|uniprotkb:Q9NQ73|uniprotkb:Q9NUN9|ensembl:ENSP00000362013 psi-mi:sox2_human(display_long)|uniprotkb:SOX2(gene name)|psi-mi:SOX2(display_short) psi-mi:tref1_human(display_long)|uniprotkb:TRERF1(gene name)|psi-mi:TRERF1(display_short)|uniprotkb:BCAR2(gene name synonym)|uniprotkb:RAPA(gene name synonym)|uniprotkb:TREP132(gene name synonym)|uniprotkb:Breast cancer anti-estrogen resistance 2(gene name synonym)|uniprotkb:Transcriptional-regulating protein 132(gene name synonym)|uniprotkb:Zinc finger protein rapa(gene name synonym)|uniprotkb:Zinc finger transcription factor TReP-132(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Cox et al. (2012) pubmed:23667531|imex:IM-28599 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-26574619|imex:IM-28599-5 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_003097.1|dip:DIP-59913N|ensembl:ENSG00000181449(gene)|ensembl:ENST00000325404(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001649"(osteoblast differentiation)|go:"GO:0001654"(eye development)|go:"GO:0001714"(endodermal cell fate specification)|go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006325"(chromatin organization)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0009611"(response to wounding)|go:"GO:0009653"(anatomical structure morphogenesis)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0021781"(glial cell fate commitment)|go:"GO:0021983"(pituitary gland development)|go:"GO:0021984"(adenohypophysis development)|go:"GO:0022409"(positive regulation of cell-cell adhesion)|go:"GO:0030154"(cell differentiation)|go:"GO:0030900"(forebrain development)|go:"GO:0035019"(somatic stem cell population maintenance)|go:"GO:0035198"(miRNA binding)|go:"GO:0042246"(tissue regeneration)|go:"GO:0043281"(regulation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0043410"(positive regulation of MAPK cascade)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045165"(cell fate commitment)|go:"GO:0045597"(positive regulation of cell differentiation)|go:"GO:0045665"(negative regulation of neuron differentiation)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048839"(inner ear development)|go:"GO:0050680"(negative regulation of epithelial cell proliferation)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0070848"(response to growth factor)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:0097150"(neuronal stem cell population maintenance)|interpro:IPR009071(High mobility group box, HMG)|interpro:IPR022097|interpro:IPR032643|interpro:IPR036910|mint:P48431|rcsb pdb:1O4X|rcsb pdb:2LE4|rcsb pdb:6T7B|rcsb pdb:6T90|rcsb pdb:6WX7|rcsb pdb:6WX8|rcsb pdb:6WX9|rcsb pdb:6YOV|reactome:R-HSA-2892245|reactome:R-HSA-2892247|reactome:R-HSA-3769402|reactome:R-HSA-452723|reactome:R-HSA-6785807|reactome:R-HSA-8986944 refseq:NP_277037.1|ensembl:ENST00000340840|ensembl:ENSP00000339438|ensembl:ENST00000354325|ensembl:ENSP00000346285|ensembl:ENST00000372917|ensembl:ENSP00000362008|ensembl:ENSP00000362013|go:"GO:0016575"(histone deacetylation)|go:"GO:0030374"(nuclear receptor coactivator activity)|go:"GO:0033142"(progesterone receptor binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|go:"GO:0050847"(progesterone receptor signaling pathway)|go:"GO:0071393"(cellular response to progesterone stimulus)|interpro:IPR000949(ELM2)|interpro:IPR001005(SANT, DNA-binding)|interpro:IPR009057(Homeodomain-like)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR017884|interpro:IPR036236|mint:Q96PN7|ensembl:ENSG00000124496(gene)|ensembl:ENST00000372922(transcript)|go:"GO:0000118"(histone deacetylase complex)|go:"GO:0001223"(transcription coactivator binding)|go:"GO:0001650"(fibrillar center)|go:"GO:0003677"(DNA binding)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005829"(cytosol)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|refseq:NP_001284502.1|refseq:XP_016866538.1|refseq:XP_016866541.1|refseq:XP_016866542.1|refseq:XP_016866543.1 go:"GO:0005634"(nucleus) - - figure legend:ST2 F2A|comment:proteins identified only in our induced samples in three MudPIT analyses with the more stringent BY-adjusted significance p<0.05|dataset:Brain Disease - Neurological Diseases & Disorders|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-daoy)|taxid:9606(Homo sapiens DAOY cerebellar medulloblastoma cell line) - 2020/12/29 2020/12/29 rogid:cn8gYfKDpQc8J2ygnqny32sIyyU9606 rogid:n4wARYaY9Lkkw7VEm9qMmF2Zw4A9606 rigid:6EMs5+B89Q89RCR/2S2BG6PhH9E false tandem tag:n-n - - - psi-mi:"MI:0658"(multidimensional protein identification technology) psi-mi:"MI:0658"(multidimensional protein identification technology) uniprotkb:P48431 uniprotkb:P07996 intact:EBI-6124081|uniprotkb:Q14537|ensembl:ENSP00000323588 intact:EBI-2530274|uniprotkb:A8K6H4|uniprotkb:B9EGH6|uniprotkb:Q15667|ensembl:ENSP00000260356|uniprotkb:B4E3J7|uniprotkb:Q59E99 psi-mi:sox2_human(display_long)|uniprotkb:SOX2(gene name)|psi-mi:SOX2(display_short) psi-mi:tsp1_human(display_long)|uniprotkb:THBS1(gene name)|psi-mi:THBS1(display_short)|uniprotkb:TSP(gene name synonym)|uniprotkb:TSP1(gene name synonym)|uniprotkb:Glycoprotein G(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Cox et al. (2012) pubmed:23667531|imex:IM-28599 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-26574619|imex:IM-28599-5 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_003097.1|dip:DIP-59913N|ensembl:ENSG00000181449(gene)|ensembl:ENST00000325404(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001649"(osteoblast differentiation)|go:"GO:0001654"(eye development)|go:"GO:0001714"(endodermal cell fate specification)|go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006325"(chromatin organization)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0009611"(response to wounding)|go:"GO:0009653"(anatomical structure morphogenesis)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0021781"(glial cell fate commitment)|go:"GO:0021983"(pituitary gland development)|go:"GO:0021984"(adenohypophysis development)|go:"GO:0022409"(positive regulation of cell-cell adhesion)|go:"GO:0030154"(cell differentiation)|go:"GO:0030900"(forebrain development)|go:"GO:0035019"(somatic stem cell population maintenance)|go:"GO:0035198"(miRNA binding)|go:"GO:0042246"(tissue regeneration)|go:"GO:0043281"(regulation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0043410"(positive regulation of MAPK cascade)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045165"(cell fate commitment)|go:"GO:0045597"(positive regulation of cell differentiation)|go:"GO:0045665"(negative regulation of neuron differentiation)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048839"(inner ear development)|go:"GO:0050680"(negative regulation of epithelial cell proliferation)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0070848"(response to growth factor)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:0097150"(neuronal stem cell population maintenance)|interpro:IPR009071(High mobility group box, HMG)|interpro:IPR022097|interpro:IPR032643|interpro:IPR036910|mint:P48431|rcsb pdb:1O4X|rcsb pdb:2LE4|rcsb pdb:6T7B|rcsb pdb:6T90|rcsb pdb:6WX7|rcsb pdb:6WX8|rcsb pdb:6WX9|rcsb pdb:6YOV|reactome:R-HSA-2892245|reactome:R-HSA-2892247|reactome:R-HSA-3769402|reactome:R-HSA-452723|reactome:R-HSA-6785807|reactome:R-HSA-8986944 ensembl:ENSG00000137801(gene)|ensembl:ENST00000260356(transcript)|go:"GO:0001666"(response to hypoxia)|go:"GO:0001786"(phosphatidylserine binding)|go:"GO:0001937"(negative regulation of endothelial cell proliferation)|go:"GO:0001953"(negative regulation of cell-matrix adhesion)|go:"GO:0001968"(fibronectin binding)|go:"GO:0002040"(sprouting angiogenesis)|go:"GO:0002544"(chronic inflammatory response)|go:"GO:0002581"(negative regulation of antigen processing and presentation of peptide or polysaccharide antigen via MHC class II)|go:"GO:0002605"(negative regulation of dendritic cell antigen processing and presentation)|go:"GO:0005178"(integrin binding)|go:"GO:0005201"(extracellular matrix structural constituent)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005577"(fibrinogen complex)|go:"GO:0005615"(extracellular space)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005788"(endoplasmic reticulum lumen)|go:"GO:0006954"(inflammatory response)|go:"GO:0006955"(immune response)|go:"GO:0006986"(response to unfolded protein)|go:"GO:0007155"(cell adhesion)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0009612"(response to mechanical stimulus)|go:"GO:0009749"(response to glucose)|go:"GO:0009897"(external side of plasma membrane)|go:"GO:0009986"(cell surface)|go:"GO:0010595"(positive regulation of endothelial cell migration)|go:"GO:0010596"(negative regulation of endothelial cell migration)|go:"GO:0010748"(negative regulation of long-chain fatty acid import across plasma membrane)|go:"GO:0010751"(negative regulation of nitric oxide mediated signal transduction)|go:"GO:0010754"(negative regulation of cGMP-mediated signaling)|go:"GO:0010757"(negative regulation of plasminogen activation)|go:"GO:0010759"(positive regulation of macrophage chemotaxis)|go:"GO:0010763"(positive regulation of fibroblast migration)|go:"GO:0016477"(cell migration)|go:"GO:0016525"(negative regulation of angiogenesis)|go:"GO:0016529"(sarcoplasmic reticulum)|go:"GO:0017134"(fibroblast growth factor binding)|go:"GO:0018149"(peptide cross-linking)|go:"GO:0030141"(secretory granule)|go:"GO:0030169"(low-density lipoprotein particle binding)|go:"GO:0030194"(positive regulation of blood coagulation)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0030511"(positive regulation of transforming growth factor beta receptor signaling pathway)|go:"GO:0031012"(extracellular matrix)|go:"GO:0031091"(platelet alpha granule)|go:"GO:0031093"(platelet alpha granule lumen)|go:"GO:0032026"(response to magnesium ion)|go:"GO:0032570"(response to progesterone)|go:"GO:0032695"(negative regulation of interleukin-12 production)|go:"GO:0008201"(heparin binding)|go:"GO:0032760"(positive regulation of tumor necrosis factor production)|go:"GO:0043154"(negative regulation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0043236"(laminin binding)|go:"GO:0043394"(proteoglycan binding)|go:"GO:0043406"(positive regulation of MAP kinase activity)|go:"GO:0043536"(positive regulation of blood vessel endothelial cell migration)|go:"GO:0043537"(negative regulation of blood vessel endothelial cell migration)|go:"GO:0043652"(engulfment of apoptotic cell)|go:"GO:0045727"(positive regulation of translation)|go:"GO:0045766"(positive regulation of angiogenesis)|go:"GO:0048266"(behavioral response to pain)|go:"GO:0048661"(positive regulation of smooth muscle cell proliferation)|go:"GO:0050431"(transforming growth factor beta binding)|go:"GO:0050921"(positive regulation of chemotaxis)|go:"GO:0032914"(positive regulation of transforming growth factor beta1 production)|go:"GO:0033574"(response to testosterone)|go:"GO:0034605"(cellular response to heat)|go:"GO:0034976"(response to endoplasmic reticulum stress)|go:"GO:0040037"(negative regulation of fibroblast growth factor receptor signaling pathway)|go:"GO:0042327"(positive regulation of phosphorylation)|go:"GO:0042493"|go:"GO:0042802"(identical protein binding)|go:"GO:0043032"(positive regulation of macrophage activation)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0051592"(response to calcium ion)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0051895"(negative regulation of focal adhesion assembly)|go:"GO:0051897"(positive regulation of protein kinase B signaling)|go:"GO:0051918"(negative regulation of fibrinolysis)|go:"GO:0062023"(collagen-containing extracellular matrix)|go:"GO:0070051"(fibrinogen binding)|go:"GO:0070052"(collagen V binding)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071356"(cellular response to tumor necrosis factor)|go:"GO:0071363"(cellular response to growth factor stimulus)|go:"GO:0090051"(negative regulation of cell migration involved in sprouting angiogenesis)|go:"GO:1902043"(positive regulation of extrinsic apoptotic signaling pathway via death domain receptors)|go:"GO:1903671"(negative regulation of sprouting angiogenesis)|go:"GO:2000353"(positive regulation of endothelial cell apoptotic process)|go:"GO:2000379"(positive regulation of reactive oxygen species metabolic process)|go:"GO:2001027"(negative regulation of endothelial cell chemotaxis)|go:"GO:2001237"(negative regulation of extrinsic apoptotic signaling pathway)|interpro:IPR000742(EGF-like, type 3)|interpro:IPR000884(Thrombospondin, type I)|interpro:IPR001007(von Willebrand factor, type C)|interpro:IPR001791(Laminin G)|interpro:IPR001881(EGF-like calcium-binding)|interpro:IPR003367(Thrombospondin type 3 repeat)|interpro:IPR008859(Thrombospondin, C-terminal)|interpro:IPR013320(Concanavalin A-like lectin/glucanase, subgroup)|interpro:IPR017897|interpro:IPR028499|interpro:IPR028974|interpro:IPR036383|mint:P07996|rcsb pdb:1LSL|rcsb pdb:1UX6|rcsb pdb:1Z78|rcsb pdb:1ZA4|rcsb pdb:2ERF|rcsb pdb:2ES3|rcsb pdb:2OUH|rcsb pdb:2OUJ|rcsb pdb:3R6B|rcsb pdb:5FOE|reactome:R-HSA-114608|reactome:R-HSA-186797|go:"GO:1903588"(negative regulation of blood vessel endothelial cell proliferation involved in sprouting angiogenesis)|reactome:R-HSA-216083|reactome:R-HSA-3000170|reactome:R-HSA-5083635|reactome:R-HSA-5173214|reactome:R-HSA-8936459|refseq:NP_003237.2|dip:DIP-1037N go:"GO:0005634"(nucleus) - - figure legend:ST2 F2A|comment:proteins identified only in our induced samples in three MudPIT analyses with the more stringent BY-adjusted significance p<0.05|dataset:Brain Disease - Neurological Diseases & Disorders|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-daoy)|taxid:9606(Homo sapiens DAOY cerebellar medulloblastoma cell line) - 2020/12/29 2020/12/29 rogid:cn8gYfKDpQc8J2ygnqny32sIyyU9606 rogid:wqgWk4yWvhfEjrD+H6BdJrJgVgg9606 rigid:6EMs5+B89Q89RCR/2S2BG6PhH9E false tandem tag:n-n - - - psi-mi:"MI:0658"(multidimensional protein identification technology) psi-mi:"MI:0658"(multidimensional protein identification technology) uniprotkb:P48431 uniprotkb:Q86US8 intact:EBI-6124081|uniprotkb:Q14537|ensembl:ENSP00000323588 intact:EBI-3232100|ensembl:ENSP00000263073|uniprotkb:O94837|uniprotkb:Q9UF60|uniprotkb:Q86VH6|uniprotkb:B7Z874 psi-mi:sox2_human(display_long)|uniprotkb:SOX2(gene name)|psi-mi:SOX2(display_short) psi-mi:est1a_human(display_long)|uniprotkb:SMG6(gene name)|psi-mi:SMG6(display_short)|uniprotkb:C17orf31(gene name synonym)|uniprotkb:EST1A(gene name synonym)|uniprotkb:KIAA0732(gene name synonym)|uniprotkb:EST1-like protein A(gene name synonym)|uniprotkb:Ever shorter telomeres 1A(gene name synonym)|uniprotkb:Smg-6 homolog(gene name synonym)|uniprotkb:Telomerase subunit EST1A(gene name synonym)|uniprotkb:hSmg5/7a(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Cox et al. (2012) pubmed:23667531|imex:IM-28599 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-26574619|imex:IM-28599-5 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_003097.1|dip:DIP-59913N|ensembl:ENSG00000181449(gene)|ensembl:ENST00000325404(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001649"(osteoblast differentiation)|go:"GO:0001654"(eye development)|go:"GO:0001714"(endodermal cell fate specification)|go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006325"(chromatin organization)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0009611"(response to wounding)|go:"GO:0009653"(anatomical structure morphogenesis)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0021781"(glial cell fate commitment)|go:"GO:0021983"(pituitary gland development)|go:"GO:0021984"(adenohypophysis development)|go:"GO:0022409"(positive regulation of cell-cell adhesion)|go:"GO:0030154"(cell differentiation)|go:"GO:0030900"(forebrain development)|go:"GO:0035019"(somatic stem cell population maintenance)|go:"GO:0035198"(miRNA binding)|go:"GO:0042246"(tissue regeneration)|go:"GO:0043281"(regulation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0043410"(positive regulation of MAPK cascade)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045165"(cell fate commitment)|go:"GO:0045597"(positive regulation of cell differentiation)|go:"GO:0045665"(negative regulation of neuron differentiation)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048839"(inner ear development)|go:"GO:0050680"(negative regulation of epithelial cell proliferation)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0070848"(response to growth factor)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:0097150"(neuronal stem cell population maintenance)|interpro:IPR009071(High mobility group box, HMG)|interpro:IPR022097|interpro:IPR032643|interpro:IPR036910|mint:P48431|rcsb pdb:1O4X|rcsb pdb:2LE4|rcsb pdb:6T7B|rcsb pdb:6T90|rcsb pdb:6WX7|rcsb pdb:6WX8|rcsb pdb:6WX9|rcsb pdb:6YOV|reactome:R-HSA-2892245|reactome:R-HSA-2892247|reactome:R-HSA-3769402|reactome:R-HSA-452723|reactome:R-HSA-6785807|reactome:R-HSA-8986944 ensembl:ENST00000263073(transcript)|go:"GO:0000184"(nuclear-transcribed mRNA catabolic process, nonsense-mediated decay)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0003723"(RNA binding)|go:"GO:0004521"(endoribonuclease activity)|go:"GO:0005634"(nucleus)|go:"GO:0005697"(telomerase holoenzyme complex)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006406"(mRNA export from nucleus)|go:"GO:0032204"(regulation of telomere maintenance)|go:"GO:0032210"(regulation of telomere maintenance via telomerase)|go:"GO:0035303"(regulation of dephosphorylation)|go:"GO:0042162"(telomeric DNA binding)|go:"GO:0043021"(ribonucleoprotein complex binding)|go:"GO:0046872"(metal ion binding)|go:"GO:0051972"(regulation of telomerase activity)|go:"GO:0070034"(telomerase RNA binding)|go:"GO:0070182"(DNA polymerase binding)|go:"GO:1904354"(negative regulation of telomere capping)|interpro:IPR002716(PilT protein, N-terminal)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR018834|interpro:IPR019458|interpro:IPR029060|mint:Q86US8|rcsb pdb:2DOK|rcsb pdb:2HWW|rcsb pdb:2HWX|rcsb pdb:4UM2|reactome:R-HSA-975957|ensembl:ENSG00000070366(gene)|refseq:XP_011522071.1|refseq:XP_011522077.1|refseq:NP_060045.4|refseq:NP_001243756.1|refseq:NP_001243757.1|refseq:NP_001269255.1|refseq:XP_005256626.1|refseq:XP_005256628.1|refseq:XP_016879888.1 go:"GO:0005634"(nucleus) - - figure legend:ST2 F2A|comment:proteins identified only in our induced samples in three MudPIT analyses with the more stringent BY-adjusted significance p<0.05|dataset:Brain Disease - Neurological Diseases & Disorders|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-daoy)|taxid:9606(Homo sapiens DAOY cerebellar medulloblastoma cell line) - 2020/12/29 2020/12/29 rogid:cn8gYfKDpQc8J2ygnqny32sIyyU9606 rogid:UoAA9ikMFv3EHZZozUAOkWWPrRM9606 rigid:6EMs5+B89Q89RCR/2S2BG6PhH9E false tandem tag:n-n - - - psi-mi:"MI:0658"(multidimensional protein identification technology) psi-mi:"MI:0658"(multidimensional protein identification technology) uniprotkb:P48431 uniprotkb:Q9HCK1 intact:EBI-6124081|uniprotkb:Q14537|ensembl:ENSP00000323588 intact:EBI-11339924|uniprotkb:Q6ZNP7|uniprotkb:Q6ZSN8|ensembl:ENSP00000363545|ensembl:ENSP00000490610|ensembl:ENSP00000497308|ensembl:ENSP00000498089 psi-mi:sox2_human(display_long)|uniprotkb:SOX2(gene name)|psi-mi:SOX2(display_short) psi-mi:zdbf2_human(display_long)|uniprotkb:ZDBF2(gene name)|psi-mi:ZDBF2(display_short)|uniprotkb:KIAA1571(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Cox et al. (2012) pubmed:23667531|imex:IM-28599 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-26574619|imex:IM-28599-5 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_003097.1|dip:DIP-59913N|ensembl:ENSG00000181449(gene)|ensembl:ENST00000325404(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001649"(osteoblast differentiation)|go:"GO:0001654"(eye development)|go:"GO:0001714"(endodermal cell fate specification)|go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006325"(chromatin organization)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0009611"(response to wounding)|go:"GO:0009653"(anatomical structure morphogenesis)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0021781"(glial cell fate commitment)|go:"GO:0021983"(pituitary gland development)|go:"GO:0021984"(adenohypophysis development)|go:"GO:0022409"(positive regulation of cell-cell adhesion)|go:"GO:0030154"(cell differentiation)|go:"GO:0030900"(forebrain development)|go:"GO:0035019"(somatic stem cell population maintenance)|go:"GO:0035198"(miRNA binding)|go:"GO:0042246"(tissue regeneration)|go:"GO:0043281"(regulation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0043410"(positive regulation of MAPK cascade)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045165"(cell fate commitment)|go:"GO:0045597"(positive regulation of cell differentiation)|go:"GO:0045665"(negative regulation of neuron differentiation)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048839"(inner ear development)|go:"GO:0050680"(negative regulation of epithelial cell proliferation)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0070848"(response to growth factor)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:0097150"(neuronal stem cell population maintenance)|interpro:IPR009071(High mobility group box, HMG)|interpro:IPR022097|interpro:IPR032643|interpro:IPR036910|mint:P48431|rcsb pdb:1O4X|rcsb pdb:2LE4|rcsb pdb:6T7B|rcsb pdb:6T90|rcsb pdb:6WX7|rcsb pdb:6WX8|rcsb pdb:6WX9|rcsb pdb:6YOV|reactome:R-HSA-2892245|reactome:R-HSA-2892247|reactome:R-HSA-3769402|reactome:R-HSA-452723|reactome:R-HSA-6785807|reactome:R-HSA-8986944 refseq:NP_065974.1|refseq:XP_005246768.1|refseq:XP_005246769.1|refseq:XP_005246770.1|refseq:XP_006712719.1|refseq:XP_011509834.1|refseq:XP_011509835.1|refseq:XP_011509836.1|refseq:XP_011509837.1|ensembl:ENSP00000363545|ensembl:ENSP00000490610|ensembl:ENSP00000497308|ensembl:ENSP00000498089|ensembl:ENSG00000204186(gene)|ensembl:ENSG00000283649(gene)|ensembl:ENST00000374423(transcript)|ensembl:ENST00000636761(transcript)|ensembl:ENST00000649650(transcript)|ensembl:ENST00000649768(transcript)|go:"GO:0003676"(nucleic acid binding)|go:"GO:0008270"(zinc ion binding)|interpro:IPR006572(Zinc finger, DBF-type)|interpro:IPR038545|interpro:IPR038890|mint:Q9HCK1 go:"GO:0005634"(nucleus) - - figure legend:ST2 F2A|comment:proteins identified only in our induced samples in three MudPIT analyses with the more stringent BY-adjusted significance p<0.05|dataset:Brain Disease - Neurological Diseases & Disorders|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-daoy)|taxid:9606(Homo sapiens DAOY cerebellar medulloblastoma cell line) - 2020/12/29 2020/12/29 rogid:cn8gYfKDpQc8J2ygnqny32sIyyU9606 rogid:ShO2N3gLMpaq/+fKBkxAK083g5w9606 rigid:6EMs5+B89Q89RCR/2S2BG6PhH9E false tandem tag:n-n - - - psi-mi:"MI:0658"(multidimensional protein identification technology) psi-mi:"MI:0658"(multidimensional protein identification technology) uniprotkb:P48431 uniprotkb:Q6P1X5 intact:EBI-6124081|uniprotkb:Q14537|ensembl:ENSP00000323588 intact:EBI-1560063|uniprotkb:O43487|uniprotkb:O43604|uniprotkb:O60668|uniprotkb:Q86WW7|uniprotkb:Q8IWK4|uniprotkb:B2RE82|ensembl:ENSP00000367406 psi-mi:sox2_human(display_long)|uniprotkb:SOX2(gene name)|psi-mi:SOX2(display_short) psi-mi:taf2_human(display_long)|uniprotkb:Transcription initiation factor TFIID 150 kDa subunit(gene name synonym)|uniprotkb:TBP-associated factor 150 kDa(gene name synonym)|uniprotkb:150 kDa cofactor of initiator function(gene name synonym)|uniprotkb:RNA polymerase II TBP-associated factor subunit B(gene name synonym)|uniprotkb:TAF2(gene name)|psi-mi:TAF2(display_short)|uniprotkb:CIF150(gene name synonym)|uniprotkb:TAF2B(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Cox et al. (2012) pubmed:23667531|imex:IM-28599 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-26574619|imex:IM-28599-5 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_003097.1|dip:DIP-59913N|ensembl:ENSG00000181449(gene)|ensembl:ENST00000325404(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001649"(osteoblast differentiation)|go:"GO:0001654"(eye development)|go:"GO:0001714"(endodermal cell fate specification)|go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006325"(chromatin organization)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0009611"(response to wounding)|go:"GO:0009653"(anatomical structure morphogenesis)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0021781"(glial cell fate commitment)|go:"GO:0021983"(pituitary gland development)|go:"GO:0021984"(adenohypophysis development)|go:"GO:0022409"(positive regulation of cell-cell adhesion)|go:"GO:0030154"(cell differentiation)|go:"GO:0030900"(forebrain development)|go:"GO:0035019"(somatic stem cell population maintenance)|go:"GO:0035198"(miRNA binding)|go:"GO:0042246"(tissue regeneration)|go:"GO:0043281"(regulation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0043410"(positive regulation of MAPK cascade)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045165"(cell fate commitment)|go:"GO:0045597"(positive regulation of cell differentiation)|go:"GO:0045665"(negative regulation of neuron differentiation)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048839"(inner ear development)|go:"GO:0050680"(negative regulation of epithelial cell proliferation)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0070848"(response to growth factor)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:0097150"(neuronal stem cell population maintenance)|interpro:IPR009071(High mobility group box, HMG)|interpro:IPR022097|interpro:IPR032643|interpro:IPR036910|mint:P48431|rcsb pdb:1O4X|rcsb pdb:2LE4|rcsb pdb:6T7B|rcsb pdb:6T90|rcsb pdb:6WX7|rcsb pdb:6WX8|rcsb pdb:6WX9|rcsb pdb:6YOV|reactome:R-HSA-2892245|reactome:R-HSA-2892247|reactome:R-HSA-3769402|reactome:R-HSA-452723|reactome:R-HSA-6785807|reactome:R-HSA-8986944 refseq:NP_003175.1|dip:DIP-38921N|ensembl:ENSG00000064313(gene)|ensembl:ENST00000378164(transcript)|go:"GO:0000086"(G2/M transition of mitotic cell cycle)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005669"(transcription factor TFIID complex)|go:"GO:0006367"(transcription initiation from RNA polymerase II promoter)|go:"GO:0014070"(response to organic cyclic compound)|go:"GO:0016251"(RNA polymerase II general transcription initiation factor activity)|go:"GO:0033276"(transcription factor TFTC complex)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR027268|interpro:IPR037813|interpro:IPR042097|mint:Q6P1X5|rcsb pdb:5FUR|rcsb pdb:6MZC|rcsb pdb:6MZL|rcsb pdb:6MZM|rcsb pdb:7EDX|rcsb pdb:7EG7|rcsb pdb:7EG8|rcsb pdb:7EG9|rcsb pdb:7EGA|rcsb pdb:7EGB|rcsb pdb:7EGC|rcsb pdb:7EGD|rcsb pdb:7EGE|rcsb pdb:7EGH|rcsb pdb:7EGI|rcsb pdb:7EGJ|rcsb pdb:7ENA|rcsb pdb:7ENC|reactome:R-HSA-167161|reactome:R-HSA-167162|reactome:R-HSA-167172|reactome:R-HSA-674695|reactome:R-HSA-6804756|reactome:R-HSA-73776|reactome:R-HSA-73779|reactome:R-HSA-75953|reactome:R-HSA-76042 go:"GO:0005634"(nucleus) - - figure legend:ST2 F2A|comment:proteins identified only in our induced samples in three MudPIT analyses with the more stringent BY-adjusted significance p<0.05|dataset:Brain Disease - Neurological Diseases & Disorders|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-daoy)|taxid:9606(Homo sapiens DAOY cerebellar medulloblastoma cell line) - 2020/12/29 2020/12/29 rogid:cn8gYfKDpQc8J2ygnqny32sIyyU9606 rogid:3MPkpqVRwuY2SiUxjQkcRFlq1RM9606 rigid:6EMs5+B89Q89RCR/2S2BG6PhH9E false tandem tag:n-n - - - psi-mi:"MI:0658"(multidimensional protein identification technology) psi-mi:"MI:0658"(multidimensional protein identification technology) uniprotkb:P48431 uniprotkb:Q8N1F7 intact:EBI-6124081|uniprotkb:Q14537|ensembl:ENSP00000323588 intact:EBI-1042703|uniprotkb:Q14705|uniprotkb:B3KPQ8|ensembl:ENSP00000310668 psi-mi:sox2_human(display_long)|uniprotkb:SOX2(gene name)|psi-mi:SOX2(display_short) psi-mi:nup93_human(display_long)|uniprotkb:NUP93(gene name)|psi-mi:NUP93(display_short)|uniprotkb:KIAA0095(gene name synonym)|uniprotkb:Nucleoporin Nup93(gene name synonym)|uniprotkb:93 kDa nucleoporin(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Cox et al. (2012) pubmed:23667531|imex:IM-28599 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-26574619|imex:IM-28599-5 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_003097.1|dip:DIP-59913N|ensembl:ENSG00000181449(gene)|ensembl:ENST00000325404(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001649"(osteoblast differentiation)|go:"GO:0001654"(eye development)|go:"GO:0001714"(endodermal cell fate specification)|go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006325"(chromatin organization)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0009611"(response to wounding)|go:"GO:0009653"(anatomical structure morphogenesis)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0021781"(glial cell fate commitment)|go:"GO:0021983"(pituitary gland development)|go:"GO:0021984"(adenohypophysis development)|go:"GO:0022409"(positive regulation of cell-cell adhesion)|go:"GO:0030154"(cell differentiation)|go:"GO:0030900"(forebrain development)|go:"GO:0035019"(somatic stem cell population maintenance)|go:"GO:0035198"(miRNA binding)|go:"GO:0042246"(tissue regeneration)|go:"GO:0043281"(regulation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0043410"(positive regulation of MAPK cascade)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045165"(cell fate commitment)|go:"GO:0045597"(positive regulation of cell differentiation)|go:"GO:0045665"(negative regulation of neuron differentiation)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048839"(inner ear development)|go:"GO:0050680"(negative regulation of epithelial cell proliferation)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0070848"(response to growth factor)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:0097150"(neuronal stem cell population maintenance)|interpro:IPR009071(High mobility group box, HMG)|interpro:IPR022097|interpro:IPR032643|interpro:IPR036910|mint:P48431|rcsb pdb:1O4X|rcsb pdb:2LE4|rcsb pdb:6T7B|rcsb pdb:6T90|rcsb pdb:6WX7|rcsb pdb:6WX8|rcsb pdb:6WX9|rcsb pdb:6YOV|reactome:R-HSA-2892245|reactome:R-HSA-2892247|reactome:R-HSA-3769402|reactome:R-HSA-452723|reactome:R-HSA-6785807|reactome:R-HSA-8986944 refseq:NP_055484.3|refseq:NP_001229724.1|refseq:NP_001229725.1|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0006998"(nuclear envelope organization)|go:"GO:0016020"(membrane)|go:"GO:0016973"("poly(A)+ mRNA export from nucleus")|go:"GO:0017056"(structural constituent of nuclear pore)|go:"GO:0031965"(nuclear membrane)|go:"GO:0034399"(nuclear periphery)|go:"GO:0051292"(nuclear pore complex assembly)|go:"GO:0060391"(positive regulation of SMAD protein signal transduction)|go:"GO:0060395"(SMAD protein signal transduction)|interpro:IPR007231(Nucleoporin interacting component)|mint:Q8N1F7|rcsb pdb:5IJN|rcsb pdb:5IJO|reactome:R-HSA-1169408|reactome:R-HSA-159227|reactome:R-HSA-159230|reactome:R-HSA-159231|reactome:R-HSA-159236|reactome:R-HSA-165054|ensembl:ENSG00000102900(gene)|reactome:R-HSA-168271|ensembl:ENST00000308159(transcript)|go:"GO:0005635"(nuclear envelope)|reactome:R-HSA-168276|go:"GO:0005643"(nuclear pore)|reactome:R-HSA-168325|reactome:R-HSA-168333|reactome:R-HSA-170822|reactome:R-HSA-180746|reactome:R-HSA-180910|reactome:R-HSA-3108214|reactome:R-HSA-3232142|reactome:R-HSA-3301854|reactome:R-HSA-3371453|reactome:R-HSA-191859|reactome:R-HSA-4085377|reactome:R-HSA-4551638|reactome:R-HSA-4570464|reactome:R-HSA-4615885|reactome:R-HSA-5578749|reactome:R-HSA-5619107|reactome:R-HSA-6784531|reactome:R-HSA-9609690|reactome:R-HSA-9610379|reactome:R-HSA-9615933|refseq:XP_005256320.1|dip:DIP-44020N go:"GO:0005634"(nucleus) - - figure legend:ST2 F2A|comment:proteins identified only in our induced samples in three MudPIT analyses with the more stringent BY-adjusted significance p<0.05|dataset:Brain Disease - Neurological Diseases & Disorders|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-daoy)|taxid:9606(Homo sapiens DAOY cerebellar medulloblastoma cell line) - 2020/12/29 2020/12/29 rogid:cn8gYfKDpQc8J2ygnqny32sIyyU9606 rogid:pkk5pooUC4yQShpqjiwNLddfy149606 rigid:6EMs5+B89Q89RCR/2S2BG6PhH9E false tandem tag:n-n - - - psi-mi:"MI:0658"(multidimensional protein identification technology) psi-mi:"MI:0658"(multidimensional protein identification technology) uniprotkb:P48431 uniprotkb:Q9H0E3 intact:EBI-6124081|uniprotkb:Q14537|ensembl:ENSP00000323588 intact:EBI-922886|uniprotkb:C9K0X9|uniprotkb:Q4ZFV4|uniprotkb:Q53T46|uniprotkb:Q8WVW4|uniprotkb:Q9H9G8|uniprotkb:B7ZLM3|ensembl:ENSP00000259235 psi-mi:sox2_human(display_long)|uniprotkb:SOX2(gene name)|psi-mi:SOX2(display_short) psi-mi:sp130_human(display_long)|uniprotkb:SAP130(gene name)|psi-mi:SAP130(display_short)|uniprotkb:130 kDa Sin3-associated polypeptide(gene name synonym)|uniprotkb:Sin3-associated polypeptide p130(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Cox et al. (2012) pubmed:23667531|imex:IM-28599 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-26574619|imex:IM-28599-5 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_003097.1|dip:DIP-59913N|ensembl:ENSG00000181449(gene)|ensembl:ENST00000325404(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001649"(osteoblast differentiation)|go:"GO:0001654"(eye development)|go:"GO:0001714"(endodermal cell fate specification)|go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006325"(chromatin organization)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0009611"(response to wounding)|go:"GO:0009653"(anatomical structure morphogenesis)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0021781"(glial cell fate commitment)|go:"GO:0021983"(pituitary gland development)|go:"GO:0021984"(adenohypophysis development)|go:"GO:0022409"(positive regulation of cell-cell adhesion)|go:"GO:0030154"(cell differentiation)|go:"GO:0030900"(forebrain development)|go:"GO:0035019"(somatic stem cell population maintenance)|go:"GO:0035198"(miRNA binding)|go:"GO:0042246"(tissue regeneration)|go:"GO:0043281"(regulation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0043410"(positive regulation of MAPK cascade)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045165"(cell fate commitment)|go:"GO:0045597"(positive regulation of cell differentiation)|go:"GO:0045665"(negative regulation of neuron differentiation)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048839"(inner ear development)|go:"GO:0050680"(negative regulation of epithelial cell proliferation)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0070848"(response to growth factor)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:0097150"(neuronal stem cell population maintenance)|interpro:IPR009071(High mobility group box, HMG)|interpro:IPR022097|interpro:IPR032643|interpro:IPR036910|mint:P48431|rcsb pdb:1O4X|rcsb pdb:2LE4|rcsb pdb:6T7B|rcsb pdb:6T90|rcsb pdb:6WX7|rcsb pdb:6WX8|rcsb pdb:6WX9|rcsb pdb:6YOV|reactome:R-HSA-2892245|reactome:R-HSA-2892247|reactome:R-HSA-3769402|reactome:R-HSA-452723|reactome:R-HSA-6785807|reactome:R-HSA-8986944 refseq:NP_001139400.1|refseq:NP_078821.2|ensembl:ENSP00000259235|ensembl:ENST00000357702|ensembl:ENSP00000350333|refseq:NP_001317228.1|ensembl:ENSG00000136715(gene)|ensembl:ENST00000259235(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0016607"(nuclear speck)|go:"GO:0070822"(Sin3-type complex)|interpro:IPR024137|interpro:IPR031963|mint:Q9H0E3|reactome:R-HSA-3214847|reactome:R-HSA-427413 go:"GO:0005634"(nucleus) - - figure legend:ST2 F2A|comment:proteins identified only in our induced samples in three MudPIT analyses with the more stringent BY-adjusted significance p<0.05|dataset:Brain Disease - Neurological Diseases & Disorders|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-daoy)|taxid:9606(Homo sapiens DAOY cerebellar medulloblastoma cell line) - 2020/12/29 2020/12/29 rogid:cn8gYfKDpQc8J2ygnqny32sIyyU9606 rogid:nrJD5dL8NZNFeFecV3VKN9mDTvw9606 rigid:6EMs5+B89Q89RCR/2S2BG6PhH9E false tandem tag:n-n - - - psi-mi:"MI:0658"(multidimensional protein identification technology) psi-mi:"MI:0658"(multidimensional protein identification technology) uniprotkb:P48431 uniprotkb:O60315 intact:EBI-6124081|uniprotkb:Q14537|ensembl:ENSP00000323588 intact:EBI-717614|uniprotkb:A0JP09|uniprotkb:Q9UED1|uniprotkb:B7Z2P2|uniprotkb:F5H814|ensembl:ENSP00000386854|ensembl:ENSP00000454157|ensembl:ENSP00000487174 psi-mi:sox2_human(display_long)|uniprotkb:SOX2(gene name)|psi-mi:SOX2(display_short) psi-mi:zeb2_human(display_long)|uniprotkb:Zinc finger homeobox protein 1b(gene name synonym)|uniprotkb:Smad-interacting protein 1(gene name synonym)|uniprotkb:ZEB2(gene name)|psi-mi:ZEB2(display_short)|uniprotkb:KIAA0569(gene name synonym)|uniprotkb:SIP1(gene name synonym)|uniprotkb:ZFX1B(gene name synonym)|uniprotkb:HRIHFB2411(orf name)|uniprotkb:ZFHX1B(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Cox et al. (2012) pubmed:23667531|imex:IM-28599 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-26574619|imex:IM-28599-5 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_003097.1|dip:DIP-59913N|ensembl:ENSG00000181449(gene)|ensembl:ENST00000325404(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001649"(osteoblast differentiation)|go:"GO:0001654"(eye development)|go:"GO:0001714"(endodermal cell fate specification)|go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006325"(chromatin organization)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0009611"(response to wounding)|go:"GO:0009653"(anatomical structure morphogenesis)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0021781"(glial cell fate commitment)|go:"GO:0021983"(pituitary gland development)|go:"GO:0021984"(adenohypophysis development)|go:"GO:0022409"(positive regulation of cell-cell adhesion)|go:"GO:0030154"(cell differentiation)|go:"GO:0030900"(forebrain development)|go:"GO:0035019"(somatic stem cell population maintenance)|go:"GO:0035198"(miRNA binding)|go:"GO:0042246"(tissue regeneration)|go:"GO:0043281"(regulation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0043410"(positive regulation of MAPK cascade)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045165"(cell fate commitment)|go:"GO:0045597"(positive regulation of cell differentiation)|go:"GO:0045665"(negative regulation of neuron differentiation)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048839"(inner ear development)|go:"GO:0050680"(negative regulation of epithelial cell proliferation)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0070848"(response to growth factor)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:0097150"(neuronal stem cell population maintenance)|interpro:IPR009071(High mobility group box, HMG)|interpro:IPR022097|interpro:IPR032643|interpro:IPR036910|mint:P48431|rcsb pdb:1O4X|rcsb pdb:2LE4|rcsb pdb:6T7B|rcsb pdb:6T90|rcsb pdb:6WX7|rcsb pdb:6WX8|rcsb pdb:6WX9|rcsb pdb:6YOV|reactome:R-HSA-2892245|reactome:R-HSA-2892247|reactome:R-HSA-3769402|reactome:R-HSA-452723|reactome:R-HSA-6785807|reactome:R-HSA-8986944 refseq:NP_001165124.1|refseq:NP_055610.1|ensembl:ENST00000409487(transcript)|ensembl:ENST00000558170(transcript)|ensembl:ENST00000627532(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|ensembl:ENSG00000169554(gene)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007399"(nervous system development)|go:"GO:0019208"(phosphatase regulator activity)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045636"(positive regulation of melanocyte differentiation)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|go:"GO:0048023"(positive regulation of melanin biosynthetic process)|go:"GO:0048066"(developmental pigmentation)|go:"GO:0048856"(anatomical structure development)|go:"GO:0090263"(positive regulation of canonical Wnt signaling pathway)|go:"GO:0097324"(melanocyte migration)|go:"GO:1903056"(regulation of melanosome organization)|interpro:IPR001356(Homeobox)|interpro:IPR008598(Drought induced 19)|interpro:IPR009057(Homeodomain-like)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR036236|mint:O60315|rcsb pdb:2DA7|go:"GO:0030511"(positive regulation of transforming growth factor beta receptor signaling pathway)|refseq:XP_006712944.1|refseq:XP_006712945.1 go:"GO:0005634"(nucleus) - - figure legend:ST2 F2A|comment:proteins identified only in our induced samples in three MudPIT analyses with the more stringent BY-adjusted significance p<0.05|dataset:Brain Disease - Neurological Diseases & Disorders|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-daoy)|taxid:9606(Homo sapiens DAOY cerebellar medulloblastoma cell line) - 2020/12/29 2020/12/29 rogid:cn8gYfKDpQc8J2ygnqny32sIyyU9606 rogid:KIKq943mmyO6wbsDamXsyo0OnEo9606 rigid:6EMs5+B89Q89RCR/2S2BG6PhH9E false tandem tag:n-n - - - psi-mi:"MI:0658"(multidimensional protein identification technology) psi-mi:"MI:0658"(multidimensional protein identification technology) uniprotkb:P48431 uniprotkb:Q9H0E9 intact:EBI-6124081|uniprotkb:Q14537|ensembl:ENSP00000323588 intact:EBI-769266|uniprotkb:O43178|uniprotkb:Q15355|uniprotkb:Q58AB0|uniprotkb:Q59GN0|uniprotkb:Q969M9|intact:EBI-28979295|ensembl:ENSP00000254900 psi-mi:sox2_human(display_long)|uniprotkb:SOX2(gene name)|psi-mi:SOX2(display_short) psi-mi:brd8_human(display_long)|uniprotkb:p120(gene name synonym)|uniprotkb:Skeletal muscle abundant protein 2(gene name synonym)|uniprotkb:Skeletal muscle abundant protein(gene name synonym)|uniprotkb:Thyroid hormone receptor coactivating protein of 120 kDa(gene name synonym)|uniprotkb:BRD8(gene name)|psi-mi:BRD8(display_short)|uniprotkb:SMAP(gene name synonym)|uniprotkb:SMAP2(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Cox et al. (2012) pubmed:23667531|imex:IM-28599 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-26574619|imex:IM-28599-5 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_003097.1|dip:DIP-59913N|ensembl:ENSG00000181449(gene)|ensembl:ENST00000325404(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001649"(osteoblast differentiation)|go:"GO:0001654"(eye development)|go:"GO:0001714"(endodermal cell fate specification)|go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006325"(chromatin organization)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0009611"(response to wounding)|go:"GO:0009653"(anatomical structure morphogenesis)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0021781"(glial cell fate commitment)|go:"GO:0021983"(pituitary gland development)|go:"GO:0021984"(adenohypophysis development)|go:"GO:0022409"(positive regulation of cell-cell adhesion)|go:"GO:0030154"(cell differentiation)|go:"GO:0030900"(forebrain development)|go:"GO:0035019"(somatic stem cell population maintenance)|go:"GO:0035198"(miRNA binding)|go:"GO:0042246"(tissue regeneration)|go:"GO:0043281"(regulation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0043410"(positive regulation of MAPK cascade)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045165"(cell fate commitment)|go:"GO:0045597"(positive regulation of cell differentiation)|go:"GO:0045665"(negative regulation of neuron differentiation)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048839"(inner ear development)|go:"GO:0050680"(negative regulation of epithelial cell proliferation)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0070848"(response to growth factor)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:0097150"(neuronal stem cell population maintenance)|interpro:IPR009071(High mobility group box, HMG)|interpro:IPR022097|interpro:IPR032643|interpro:IPR036910|mint:P48431|rcsb pdb:1O4X|rcsb pdb:2LE4|rcsb pdb:6T7B|rcsb pdb:6T90|rcsb pdb:6WX7|rcsb pdb:6WX8|rcsb pdb:6WX9|rcsb pdb:6YOV|reactome:R-HSA-2892245|reactome:R-HSA-2892247|reactome:R-HSA-3769402|reactome:R-HSA-452723|reactome:R-HSA-6785807|reactome:R-HSA-8986944 refseq:NP_001157798.1|refseq:NP_006687.3|refseq:NP_631938.1|ensembl:ENST00000230901|ensembl:ENSP00000230901|ensembl:ENSP00000254900|ensembl:ENST00000411594|ensembl:ENSP00000394330|refseq:NP_001287890.1|refseq:NP_001287891.1|refseq:NP_001287895.1|dip:DIP-31762N|ensembl:ENSG00000112983(gene)|ensembl:ENST00000254900(transcript)|go:"GO:0000812"(Swr1 complex)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0007166"(cell surface receptor signaling pathway)|go:"GO:0016573"(histone acetylation)|go:"GO:0043967"(histone H4 acetylation)|go:"GO:0043968"(histone H2A acetylation)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046966"(thyroid hormone receptor binding)|go:"GO:0097067"(cellular response to thyroid hormone stimulus)|interpro:IPR001487(Bromodomain)|interpro:IPR036427|interpro:IPR037966|interpro:IPR038002|mint:Q9H0E9|reactome:R-HSA-3214847|go:"GO:0030374"(nuclear receptor coactivator activity)|go:"GO:0035267"(NuA4 histone acetyltransferase complex)|go:"GO:0040008"(regulation of growth) go:"GO:0005634"(nucleus) - - figure legend:ST2 F2A|comment:proteins identified only in our induced samples in three MudPIT analyses with the more stringent BY-adjusted significance p<0.05|dataset:Brain Disease - Neurological Diseases & Disorders|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-daoy)|taxid:9606(Homo sapiens DAOY cerebellar medulloblastoma cell line) - 2020/12/29 2020/12/29 rogid:cn8gYfKDpQc8J2ygnqny32sIyyU9606 rogid:RUJbvq7VAMg7fzpCT4Hs6/FPej49606 rigid:6EMs5+B89Q89RCR/2S2BG6PhH9E false tandem tag:n-n - - - psi-mi:"MI:0658"(multidimensional protein identification technology) psi-mi:"MI:0658"(multidimensional protein identification technology) uniprotkb:P48431 uniprotkb:Q9UPN3 intact:EBI-6124081|uniprotkb:Q14537|ensembl:ENSP00000323588 intact:EBI-522925|uniprotkb:E9PJT0|uniprotkb:O75053|uniprotkb:Q5VW20|uniprotkb:Q8WXY2|uniprotkb:Q9H540|uniprotkb:Q9UKP0|uniprotkb:Q9ULG9|intact:EBI-28967632|uniprotkb:B1ALC5|uniprotkb:Q8WXY1|uniprotkb:Q96PK2 psi-mi:sox2_human(display_long)|uniprotkb:SOX2(gene name)|psi-mi:SOX2(display_short) psi-mi:macf1_human(display_long)|uniprotkb:Actin cross-linking family protein 7(gene name synonym)|uniprotkb:Macrophin-1(gene name synonym)|uniprotkb:Trabeculin-alpha(gene name synonym)|uniprotkb:620 kDa actin-binding protein(gene name synonym)|uniprotkb:MACF1(gene name)|psi-mi:MACF1(display_short)|uniprotkb:ABP620(gene name synonym)|uniprotkb:ACF7(gene name synonym)|uniprotkb:KIAA0465(gene name synonym)|uniprotkb:KIAA1251(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Cox et al. (2012) pubmed:23667531|imex:IM-28599 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-26574619|imex:IM-28599-5 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_003097.1|dip:DIP-59913N|ensembl:ENSG00000181449(gene)|ensembl:ENST00000325404(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001649"(osteoblast differentiation)|go:"GO:0001654"(eye development)|go:"GO:0001714"(endodermal cell fate specification)|go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006325"(chromatin organization)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0009611"(response to wounding)|go:"GO:0009653"(anatomical structure morphogenesis)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0021781"(glial cell fate commitment)|go:"GO:0021983"(pituitary gland development)|go:"GO:0021984"(adenohypophysis development)|go:"GO:0022409"(positive regulation of cell-cell adhesion)|go:"GO:0030154"(cell differentiation)|go:"GO:0030900"(forebrain development)|go:"GO:0035019"(somatic stem cell population maintenance)|go:"GO:0035198"(miRNA binding)|go:"GO:0042246"(tissue regeneration)|go:"GO:0043281"(regulation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0043410"(positive regulation of MAPK cascade)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045165"(cell fate commitment)|go:"GO:0045597"(positive regulation of cell differentiation)|go:"GO:0045665"(negative regulation of neuron differentiation)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048839"(inner ear development)|go:"GO:0050680"(negative regulation of epithelial cell proliferation)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0070848"(response to growth factor)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:0097150"(neuronal stem cell population maintenance)|interpro:IPR009071(High mobility group box, HMG)|interpro:IPR022097|interpro:IPR032643|interpro:IPR036910|mint:P48431|rcsb pdb:1O4X|rcsb pdb:2LE4|rcsb pdb:6T7B|rcsb pdb:6T90|rcsb pdb:6WX7|rcsb pdb:6WX8|rcsb pdb:6WX9|rcsb pdb:6YOV|reactome:R-HSA-2892245|reactome:R-HSA-2892247|reactome:R-HSA-3769402|reactome:R-HSA-452723|reactome:R-HSA-6785807|reactome:R-HSA-8986944 ensembl:ENST00000361689|ensembl:ENSP00000354573|ensembl:ENSG00000127603|refseq:NP_036222.3|go:"GO:0045296"(cadherin binding)|go:"GO:0045773"(positive regulation of axon extension)|go:"GO:0051011"(microtubule minus-end binding)|go:"GO:0051015"(actin filament binding)|go:"GO:0051893"(regulation of focal adhesion assembly)|go:"GO:0150011"(regulation of neuron projection arborization)|interpro:IPR001101(Plectin repeat)|interpro:IPR001452(Src homology-3)|interpro:IPR001589(Actinin-type, actin-binding, conserved site)|interpro:IPR001715(Calponin-like actin-binding)|interpro:IPR002017(Spectrin repeat)|interpro:IPR002048(Calcium-binding EF-hand)|interpro:IPR003108(Growth-arrest-specific protein 2)|interpro:IPR011992(EF-Hand type)|interpro:IPR018159|interpro:IPR018247|interpro:IPR035915|interpro:IPR036534|interpro:IPR036872|interpro:IPR041573|interpro:IPR041615|interpro:IPR043197|rcsb pdb:4Z6G|rcsb pdb:5VE9|rcsb pdb:5X57|go:"GO:0003723"(RNA binding)|go:"GO:0003779"(actin binding)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005874"(microtubule)|go:"GO:0005886"(plasma membrane)|go:"GO:0010632"(regulation of epithelial cell migration)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0016020"(membrane)|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0030177"(positive regulation of Wnt signaling pathway)|go:"GO:0030334"(regulation of cell migration)|go:"GO:0032587"(ruffle membrane)|go:"GO:0032886"(regulation of microtubule-based process)|go:"GO:0042060"(wound healing)|go:"GO:0043001"(Golgi to plasma membrane protein transport)|go:"GO:0045104"(intermediate filament cytoskeleton organization)|dip:DIP-50616N|mint:Q9UPN3 go:"GO:0005634"(nucleus) - - figure legend:ST2 F2A|comment:proteins identified only in our induced samples in three MudPIT analyses with the more stringent BY-adjusted significance p<0.05|dataset:Brain Disease - Neurological Diseases & Disorders|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-daoy)|taxid:9606(Homo sapiens DAOY cerebellar medulloblastoma cell line) - 2020/12/29 2020/12/29 rogid:cn8gYfKDpQc8J2ygnqny32sIyyU9606 rogid:G5PesqPZZxQhwDgW0pBJSkJNcZ49606 rigid:6EMs5+B89Q89RCR/2S2BG6PhH9E false tandem tag:n-n - - - psi-mi:"MI:0658"(multidimensional protein identification technology) psi-mi:"MI:0658"(multidimensional protein identification technology) uniprotkb:P48431 uniprotkb:Q96AC1 intact:EBI-6124081|uniprotkb:Q14537|ensembl:ENSP00000323588 intact:EBI-4399465|ensembl:ENSP00000340391|ensembl:ENSP00000378993|uniprotkb:Q14840|uniprotkb:Q86TY7|uniprotkb:B5TJY2 psi-mi:sox2_human(display_long)|uniprotkb:SOX2(gene name)|psi-mi:SOX2(display_short) psi-mi:ferm2_human(display_long)|uniprotkb:FERMT2(gene name)|psi-mi:FERMT2(display_short)|uniprotkb:KIND2(gene name synonym)|uniprotkb:MIG2(gene name synonym)|uniprotkb:PLEKHC1(gene name synonym)|uniprotkb:Kindlin-2(gene name synonym)|uniprotkb:Mitogen-inducible gene 2 protein(gene name synonym)|uniprotkb:Pleckstrin homology domain-containing family C member 1(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Cox et al. (2012) pubmed:23667531|imex:IM-28599 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-26574619|imex:IM-28599-5 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_003097.1|dip:DIP-59913N|ensembl:ENSG00000181449(gene)|ensembl:ENST00000325404(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001649"(osteoblast differentiation)|go:"GO:0001654"(eye development)|go:"GO:0001714"(endodermal cell fate specification)|go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006325"(chromatin organization)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0009611"(response to wounding)|go:"GO:0009653"(anatomical structure morphogenesis)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0021781"(glial cell fate commitment)|go:"GO:0021983"(pituitary gland development)|go:"GO:0021984"(adenohypophysis development)|go:"GO:0022409"(positive regulation of cell-cell adhesion)|go:"GO:0030154"(cell differentiation)|go:"GO:0030900"(forebrain development)|go:"GO:0035019"(somatic stem cell population maintenance)|go:"GO:0035198"(miRNA binding)|go:"GO:0042246"(tissue regeneration)|go:"GO:0043281"(regulation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0043410"(positive regulation of MAPK cascade)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045165"(cell fate commitment)|go:"GO:0045597"(positive regulation of cell differentiation)|go:"GO:0045665"(negative regulation of neuron differentiation)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048839"(inner ear development)|go:"GO:0050680"(negative regulation of epithelial cell proliferation)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0070848"(response to growth factor)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:0097150"(neuronal stem cell population maintenance)|interpro:IPR009071(High mobility group box, HMG)|interpro:IPR022097|interpro:IPR032643|interpro:IPR036910|mint:P48431|rcsb pdb:1O4X|rcsb pdb:2LE4|rcsb pdb:6T7B|rcsb pdb:6T90|rcsb pdb:6WX7|rcsb pdb:6WX8|rcsb pdb:6WX9|rcsb pdb:6YOV|reactome:R-HSA-2892245|reactome:R-HSA-2892247|reactome:R-HSA-3769402|reactome:R-HSA-452723|reactome:R-HSA-6785807|reactome:R-HSA-8986944 ensembl:ENSG00000073712(gene)|ensembl:ENST00000341590(transcript)|ensembl:ENST00000395631(transcript)|go:"GO:0001725"(stress fiber)|refseq:NP_001128471.1|refseq:NP_001128472.1|refseq:NP_006823.1|go:"GO:0003779"(actin binding)|go:"GO:0005178"(integrin binding)|go:"GO:0005547"(phosphatidylinositol-3,4,5-trisphosphate binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005912"(adherens junction)|go:"GO:0005925"(focal adhesion)|go:"GO:0005938"(cell cortex)|go:"GO:0007155"(cell adhesion)|go:"GO:0007160"(cell-matrix adhesion)|go:"GO:0007179"(transforming growth factor beta receptor signaling pathway)|go:"GO:0007229"(integrin-mediated signaling pathway)|go:"GO:0008360"(regulation of cell shape)|go:"GO:0009986"(cell surface)|go:"GO:0010718"(positive regulation of epithelial to mesenchymal transition)|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0019901"(protein kinase binding)|go:"GO:0022604"(regulation of cell morphogenesis)|go:"GO:0030054"(cell junction)|go:"GO:0030055"(cell-substrate junction)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0031234"(extrinsic component of cytoplasmic side of plasma membrane)|go:"GO:0031258"(lamellipodium membrane)|go:"GO:0031674"(I band)|go:"GO:0033622"(integrin activation)|go:"GO:0033625"(positive regulation of integrin activation)|go:"GO:0034334"(adherens junction maintenance)|go:"GO:0034446"(substrate adhesion-dependent cell spreading)|go:"GO:0034713"(type I transforming growth factor beta receptor binding)|go:"GO:0035505"(positive regulation of myosin light chain kinase activity)|go:"GO:0043116"(negative regulation of vascular permeability)|go:"GO:0043547"(positive regulation of GTPase activity)|go:"GO:0045599"(negative regulation of fat cell differentiation)|go:"GO:0045669"(positive regulation of osteoblast differentiation)|go:"GO:0046332"(SMAD binding)|go:"GO:0048041"(focal adhesion assembly)|go:"GO:0051015"(actin filament binding)|go:"GO:0051496"(positive regulation of stress fiber assembly)|go:"GO:0051894"(positive regulation of focal adhesion assembly)|go:"GO:0051897"(positive regulation of protein kinase B signaling)|go:"GO:0060173"(limb development)|go:"GO:0060548"(negative regulation of cell death)|go:"GO:0070374"(positive regulation of ERK1 and ERK2 cascade)|go:"GO:0072657"(protein localization to membrane)|go:"GO:1900026"(positive regulation of substrate adhesion-dependent cell spreading)|go:"GO:1900182"(positive regulation of protein localization to nucleus)|go:"GO:1902414"(protein localization to cell junction)|go:"GO:1902462"(positive regulation of mesenchymal stem cell proliferation)|go:"GO:1903691"(positive regulation of wound healing, spreading of epidermal cells)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR019748|interpro:IPR019749|interpro:IPR035963|interpro:IPR037837|interpro:IPR037843|interpro:IPR040790|mint:Q96AC1|rcsb pdb:2LGX|rcsb pdb:2LKO|rcsb pdb:2MSU|rcsb pdb:4F7H|rcsb pdb:6U4N|rcsb pdb:6XTJ|reactome:R-HSA-446353|reactome:R-HSA-9013149|reactome:R-HSA-9013423 go:"GO:0005634"(nucleus) - - figure legend:ST2 F2A|comment:proteins identified only in our induced samples in three MudPIT analyses with the more stringent BY-adjusted significance p<0.05|dataset:Brain Disease - Neurological Diseases & Disorders|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-daoy)|taxid:9606(Homo sapiens DAOY cerebellar medulloblastoma cell line) - 2020/12/29 2020/12/29 rogid:cn8gYfKDpQc8J2ygnqny32sIyyU9606 rogid:nmlzKrHEw/aEw6C8i9+G/80jbuE9606 rigid:6EMs5+B89Q89RCR/2S2BG6PhH9E false tandem tag:n-n - - - psi-mi:"MI:0658"(multidimensional protein identification technology) psi-mi:"MI:0658"(multidimensional protein identification technology) uniprotkb:P48431 uniprotkb:Q9UNX4 intact:EBI-6124081|uniprotkb:Q14537|ensembl:ENSP00000323588 intact:EBI-727436|ensembl:ENSP00000308179 psi-mi:sox2_human(display_long)|uniprotkb:SOX2(gene name)|psi-mi:SOX2(display_short) psi-mi:wdr3_human(display_long)|uniprotkb:WDR3(gene name)|psi-mi:WDR3(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Cox et al. (2012) pubmed:23667531|imex:IM-28599 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-26574619|imex:IM-28599-5 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_003097.1|dip:DIP-59913N|ensembl:ENSG00000181449(gene)|ensembl:ENST00000325404(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001649"(osteoblast differentiation)|go:"GO:0001654"(eye development)|go:"GO:0001714"(endodermal cell fate specification)|go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006325"(chromatin organization)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0009611"(response to wounding)|go:"GO:0009653"(anatomical structure morphogenesis)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0021781"(glial cell fate commitment)|go:"GO:0021983"(pituitary gland development)|go:"GO:0021984"(adenohypophysis development)|go:"GO:0022409"(positive regulation of cell-cell adhesion)|go:"GO:0030154"(cell differentiation)|go:"GO:0030900"(forebrain development)|go:"GO:0035019"(somatic stem cell population maintenance)|go:"GO:0035198"(miRNA binding)|go:"GO:0042246"(tissue regeneration)|go:"GO:0043281"(regulation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0043410"(positive regulation of MAPK cascade)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045165"(cell fate commitment)|go:"GO:0045597"(positive regulation of cell differentiation)|go:"GO:0045665"(negative regulation of neuron differentiation)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048839"(inner ear development)|go:"GO:0050680"(negative regulation of epithelial cell proliferation)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0070848"(response to growth factor)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:0097150"(neuronal stem cell population maintenance)|interpro:IPR009071(High mobility group box, HMG)|interpro:IPR022097|interpro:IPR032643|interpro:IPR036910|mint:P48431|rcsb pdb:1O4X|rcsb pdb:2LE4|rcsb pdb:6T7B|rcsb pdb:6T90|rcsb pdb:6WX7|rcsb pdb:6WX8|rcsb pdb:6WX9|rcsb pdb:6YOV|reactome:R-HSA-2892245|reactome:R-HSA-2892247|reactome:R-HSA-3769402|reactome:R-HSA-452723|reactome:R-HSA-6785807|reactome:R-HSA-8986944 refseq:NP_006775.1|ensembl:ENSG00000065183(gene)|ensembl:ENST00000349139(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0030490"(maturation of SSU-rRNA)|go:"GO:0030515"(snoRNA binding)|go:"GO:0031965"(nuclear membrane)|go:"GO:0032040"(small-subunit processome)|go:"GO:0034388"(Pwp2p-containing subcomplex of 90S preribosome)|interpro:IPR001680(WD40 repeat)|interpro:IPR007148(Small-subunit processome, Utp12)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019775|interpro:IPR020472|interpro:IPR024977|interpro:IPR036322|mint:Q9UNX4|reactome:R-HSA-6790901|reactome:R-HSA-6791226 go:"GO:0005634"(nucleus) - - figure legend:ST2 F2A|comment:proteins identified only in our induced samples in three MudPIT analyses with the more stringent BY-adjusted significance p<0.05|dataset:Brain Disease - Neurological Diseases & Disorders|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-daoy)|taxid:9606(Homo sapiens DAOY cerebellar medulloblastoma cell line) - 2020/12/29 2020/12/29 rogid:cn8gYfKDpQc8J2ygnqny32sIyyU9606 rogid:aslkTiEP+9ytaN6cc+SC+TzOxUg9606 rigid:6EMs5+B89Q89RCR/2S2BG6PhH9E false tandem tag:n-n - - - psi-mi:"MI:0658"(multidimensional protein identification technology) psi-mi:"MI:0658"(multidimensional protein identification technology) uniprotkb:P48431 uniprotkb:O75182 intact:EBI-6124081|uniprotkb:Q14537|ensembl:ENSP00000323588 intact:EBI-540462|uniprotkb:Q68GC2|uniprotkb:Q6P4B8|uniprotkb:Q8TB34|uniprotkb:Q9BSC8|uniprotkb:Q2NL91|ensembl:ENSP00000369131 psi-mi:sox2_human(display_long)|uniprotkb:SOX2(gene name)|psi-mi:SOX2(display_short) psi-mi:sin3b_human(display_long)|uniprotkb:Transcriptional corepressor Sin3b(gene name synonym)|uniprotkb:Histone deacetylase complex subunit Sin3b(gene name synonym)|uniprotkb:SIN3B(gene name)|psi-mi:SIN3B(display_short)|uniprotkb:KIAA0700(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Cox et al. (2012) pubmed:23667531|imex:IM-28599 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-26574619|imex:IM-28599-5 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_003097.1|dip:DIP-59913N|ensembl:ENSG00000181449(gene)|ensembl:ENST00000325404(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001649"(osteoblast differentiation)|go:"GO:0001654"(eye development)|go:"GO:0001714"(endodermal cell fate specification)|go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006325"(chromatin organization)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0009611"(response to wounding)|go:"GO:0009653"(anatomical structure morphogenesis)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0021781"(glial cell fate commitment)|go:"GO:0021983"(pituitary gland development)|go:"GO:0021984"(adenohypophysis development)|go:"GO:0022409"(positive regulation of cell-cell adhesion)|go:"GO:0030154"(cell differentiation)|go:"GO:0030900"(forebrain development)|go:"GO:0035019"(somatic stem cell population maintenance)|go:"GO:0035198"(miRNA binding)|go:"GO:0042246"(tissue regeneration)|go:"GO:0043281"(regulation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0043410"(positive regulation of MAPK cascade)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045165"(cell fate commitment)|go:"GO:0045597"(positive regulation of cell differentiation)|go:"GO:0045665"(negative regulation of neuron differentiation)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048839"(inner ear development)|go:"GO:0050680"(negative regulation of epithelial cell proliferation)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0070848"(response to growth factor)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:0097150"(neuronal stem cell population maintenance)|interpro:IPR009071(High mobility group box, HMG)|interpro:IPR022097|interpro:IPR032643|interpro:IPR036910|mint:P48431|rcsb pdb:1O4X|rcsb pdb:2LE4|rcsb pdb:6T7B|rcsb pdb:6T90|rcsb pdb:6WX7|rcsb pdb:6WX8|rcsb pdb:6WX9|rcsb pdb:6YOV|reactome:R-HSA-2892245|reactome:R-HSA-2892247|reactome:R-HSA-3769402|reactome:R-HSA-452723|reactome:R-HSA-6785807|reactome:R-HSA-8986944 refseq:NP_056075.1|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0016575"(histone deacetylation)|go:"GO:0016580"(Sin3 complex)|go:"GO:0030849"(autosome)|interpro:IPR003822(Paired amphipathic helix)|interpro:IPR013194(Histone deacetylase interacting)|interpro:IPR031693|go:"GO:0003682"(chromatin binding)|interpro:IPR036600|interpro:IPR039774|mint:O75182|reactome:R-HSA-400206|reactome:R-HSA-427413|reactome:R-HSA-8936459|reactome:R-HSA-9707564|ensembl:ENSG00000127511(gene)|ensembl:ENST00000379803(transcript)|go:"GO:0000118"(histone deacetylase complex)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000805"(X chromosome)|go:"GO:0000806"(Y chromosome)|go:"GO:0001741"(XY body)|refseq:NP_001284524.1|refseq:NP_001284526.1 go:"GO:0005634"(nucleus) - - figure legend:ST2 F2A|comment:proteins identified only in our induced samples in three MudPIT analyses with the more stringent BY-adjusted significance p<0.05|dataset:Brain Disease - Neurological Diseases & Disorders|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-daoy)|taxid:9606(Homo sapiens DAOY cerebellar medulloblastoma cell line) - 2020/12/29 2020/12/29 rogid:cn8gYfKDpQc8J2ygnqny32sIyyU9606 rogid:ney2nq8TMh2sFxskgXr+NgNCl349606 rigid:6EMs5+B89Q89RCR/2S2BG6PhH9E false tandem tag:n-n - - - psi-mi:"MI:0658"(multidimensional protein identification technology) psi-mi:"MI:0658"(multidimensional protein identification technology) uniprotkb:P48431 uniprotkb:Q96DT7 intact:EBI-6124081|uniprotkb:Q14537|ensembl:ENSP00000323588 intact:EBI-10235384|uniprotkb:Q8IXI9|uniprotkb:Q96MH9|uniprotkb:Q86W96|uniprotkb:A4FVD0|ensembl:ENSP00000387462|ensembl:ENSP00000412036 psi-mi:sox2_human(display_long)|uniprotkb:SOX2(gene name)|psi-mi:SOX2(display_short) psi-mi:zbt10_human(display_long)|uniprotkb:ZBTB10(gene name)|psi-mi:ZBTB10(display_short)|uniprotkb:RINZF(gene name synonym)|uniprotkb:RINZFC(gene name synonym)|uniprotkb:Zinc finger protein RIN ZF(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Cox et al. (2012) pubmed:23667531|imex:IM-28599 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-26574619|imex:IM-28599-5 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_003097.1|dip:DIP-59913N|ensembl:ENSG00000181449(gene)|ensembl:ENST00000325404(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001649"(osteoblast differentiation)|go:"GO:0001654"(eye development)|go:"GO:0001714"(endodermal cell fate specification)|go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006325"(chromatin organization)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0009611"(response to wounding)|go:"GO:0009653"(anatomical structure morphogenesis)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0021781"(glial cell fate commitment)|go:"GO:0021983"(pituitary gland development)|go:"GO:0021984"(adenohypophysis development)|go:"GO:0022409"(positive regulation of cell-cell adhesion)|go:"GO:0030154"(cell differentiation)|go:"GO:0030900"(forebrain development)|go:"GO:0035019"(somatic stem cell population maintenance)|go:"GO:0035198"(miRNA binding)|go:"GO:0042246"(tissue regeneration)|go:"GO:0043281"(regulation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0043410"(positive regulation of MAPK cascade)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045165"(cell fate commitment)|go:"GO:0045597"(positive regulation of cell differentiation)|go:"GO:0045665"(negative regulation of neuron differentiation)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048839"(inner ear development)|go:"GO:0050680"(negative regulation of epithelial cell proliferation)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0070848"(response to growth factor)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:0097150"(neuronal stem cell population maintenance)|interpro:IPR009071(High mobility group box, HMG)|interpro:IPR022097|interpro:IPR032643|interpro:IPR036910|mint:P48431|rcsb pdb:1O4X|rcsb pdb:2LE4|rcsb pdb:6T7B|rcsb pdb:6T90|rcsb pdb:6WX7|rcsb pdb:6WX8|rcsb pdb:6WX9|rcsb pdb:6YOV|reactome:R-HSA-2892245|reactome:R-HSA-2892247|reactome:R-HSA-3769402|reactome:R-HSA-452723|reactome:R-HSA-6785807|reactome:R-HSA-8986944 refseq:NP_001099009.1|refseq:NP_001264074.1|refseq:NP_076418.3|ensembl:ENSG00000205189(gene)|ensembl:ENST00000430430(transcript)|ensembl:ENST00000455036(transcript)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|interpro:IPR000210(BTB/POZ-like)|interpro:IPR011333(BTB/POZ fold)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR036236|mint:Q96DT7 go:"GO:0005634"(nucleus) - - figure legend:ST2 F2A|comment:proteins identified only in our induced samples in three MudPIT analyses with the more stringent BY-adjusted significance p<0.05|dataset:Brain Disease - Neurological Diseases & Disorders|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-daoy)|taxid:9606(Homo sapiens DAOY cerebellar medulloblastoma cell line) - 2020/12/29 2020/12/29 rogid:cn8gYfKDpQc8J2ygnqny32sIyyU9606 rogid:wGypJaZ9a4cfN5Z84Aof+MAruSI9606 rigid:6EMs5+B89Q89RCR/2S2BG6PhH9E false tandem tag:n-n - - - psi-mi:"MI:0658"(multidimensional protein identification technology) psi-mi:"MI:0658"(multidimensional protein identification technology) uniprotkb:P48431 uniprotkb:Q14738 intact:EBI-6124081|uniprotkb:Q14537|ensembl:ENSP00000323588 intact:EBI-396563|uniprotkb:O00494|uniprotkb:O00696|uniprotkb:Q15171|uniprotkb:Q5TC39|uniprotkb:B5BUA6|uniprotkb:A8K3I9|ensembl:ENSP00000417963 psi-mi:sox2_human(display_long)|uniprotkb:SOX2(gene name)|psi-mi:SOX2(display_short) psi-mi:2a5d_human(display_long)|uniprotkb:PPP2R5D(gene name)|psi-mi:PPP2R5D(display_short)|uniprotkb:PP2A B subunit isoform B'-delta(gene name synonym)|uniprotkb:PP2A B subunit isoform B56-delta(gene name synonym)|uniprotkb:PP2A B subunit isoform PR61-delta(gene name synonym)|uniprotkb:PP2A B subunit isoform R5-delta(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Cox et al. (2012) pubmed:23667531|imex:IM-28599 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-26574619|imex:IM-28599-5 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_003097.1|dip:DIP-59913N|ensembl:ENSG00000181449(gene)|ensembl:ENST00000325404(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001649"(osteoblast differentiation)|go:"GO:0001654"(eye development)|go:"GO:0001714"(endodermal cell fate specification)|go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006325"(chromatin organization)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0009611"(response to wounding)|go:"GO:0009653"(anatomical structure morphogenesis)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0021781"(glial cell fate commitment)|go:"GO:0021983"(pituitary gland development)|go:"GO:0021984"(adenohypophysis development)|go:"GO:0022409"(positive regulation of cell-cell adhesion)|go:"GO:0030154"(cell differentiation)|go:"GO:0030900"(forebrain development)|go:"GO:0035019"(somatic stem cell population maintenance)|go:"GO:0035198"(miRNA binding)|go:"GO:0042246"(tissue regeneration)|go:"GO:0043281"(regulation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0043410"(positive regulation of MAPK cascade)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045165"(cell fate commitment)|go:"GO:0045597"(positive regulation of cell differentiation)|go:"GO:0045665"(negative regulation of neuron differentiation)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048839"(inner ear development)|go:"GO:0050680"(negative regulation of epithelial cell proliferation)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0070848"(response to growth factor)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:0097150"(neuronal stem cell population maintenance)|interpro:IPR009071(High mobility group box, HMG)|interpro:IPR022097|interpro:IPR032643|interpro:IPR036910|mint:P48431|rcsb pdb:1O4X|rcsb pdb:2LE4|rcsb pdb:6T7B|rcsb pdb:6T90|rcsb pdb:6WX7|rcsb pdb:6WX8|rcsb pdb:6WX9|rcsb pdb:6YOV|reactome:R-HSA-2892245|reactome:R-HSA-2892247|reactome:R-HSA-3769402|reactome:R-HSA-452723|reactome:R-HSA-6785807|reactome:R-HSA-8986944 refseq:NP_006236.1|refseq:NP_851307.1|refseq:NP_851308.1|ensembl:ENSG00000112640(gene)|ensembl:ENST00000485511(transcript)|go:"GO:0000159"(protein phosphatase type 2A complex)|go:"GO:0004721"(phosphoprotein phosphatase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006470"(protein dephosphorylation)|go:"GO:0007165"(signal transduction)|go:"GO:0007399"(nervous system development)|go:"GO:0010801"(negative regulation of peptidyl-threonine phosphorylation)|go:"GO:0019888"(protein phosphatase regulator activity)|go:"GO:0031952"(regulation of protein autophosphorylation)|go:"GO:0035307"(positive regulation of protein dephosphorylation)|go:"GO:0072542"(protein phosphatase activator activity)|interpro:IPR002554(Protein phosphatase 2A, regulatory B subunit, B56)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|mint:Q14738|reactome:R-HSA-141444|reactome:R-HSA-163685|reactome:R-HSA-163767|reactome:R-HSA-180024|reactome:R-HSA-195253|reactome:R-HSA-196299|reactome:R-HSA-198753|reactome:R-HSA-202670|reactome:R-HSA-2467813|reactome:R-HSA-2500257|reactome:R-HSA-389513|reactome:R-HSA-432142|reactome:R-HSA-4641262|reactome:R-HSA-5339716|reactome:R-HSA-5358747|reactome:R-HSA-5358749|reactome:R-HSA-5358751|reactome:R-HSA-5358752|reactome:R-HSA-5467337|reactome:R-HSA-5467340|reactome:R-HSA-5467348|reactome:R-HSA-5663220|reactome:R-HSA-5673000|reactome:R-HSA-5675221|reactome:R-HSA-6811558|reactome:R-HSA-68877|reactome:R-HSA-9634600|reactome:R-HSA-9648025|refseq:NP_001257405.1|dip:DIP-29961N go:"GO:0005634"(nucleus) - - figure legend:ST2 F2A|comment:proteins identified only in our induced samples in three MudPIT analyses with the more stringent BY-adjusted significance p<0.05|dataset:Brain Disease - Neurological Diseases & Disorders|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-daoy)|taxid:9606(Homo sapiens DAOY cerebellar medulloblastoma cell line) - 2020/12/29 2020/12/29 rogid:cn8gYfKDpQc8J2ygnqny32sIyyU9606 rogid:tQnhuUL/6Iuhcyu/B41Me1LWpr89606 rigid:6EMs5+B89Q89RCR/2S2BG6PhH9E false tandem tag:n-n - - - psi-mi:"MI:0658"(multidimensional protein identification technology) psi-mi:"MI:0658"(multidimensional protein identification technology) uniprotkb:P48431 uniprotkb:P35658 intact:EBI-6124081|uniprotkb:Q14537|ensembl:ENSP00000323588 intact:EBI-1222270|uniprotkb:A6NFQ0|uniprotkb:Q15010|uniprotkb:Q3KQZ0|uniprotkb:Q5JUP7|uniprotkb:Q75R47|uniprotkb:Q86XD3|intact:EBI-2555216|ensembl:ENSP00000352400 psi-mi:sox2_human(display_long)|uniprotkb:SOX2(gene name)|psi-mi:SOX2(display_short) psi-mi:nu214_human(display_long)|uniprotkb:NUP214(gene name)|psi-mi:NUP214(display_short)|uniprotkb:CAIN(gene name synonym)|uniprotkb:CAN(gene name synonym)|uniprotkb:KIAA0023(gene name synonym)|uniprotkb:Nucleoporin Nup214(gene name synonym)|uniprotkb:214 kDa nucleoporin(gene name synonym)|uniprotkb:Protein CAN(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Cox et al. (2012) pubmed:23667531|imex:IM-28599 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-26574619|imex:IM-28599-5 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_003097.1|dip:DIP-59913N|ensembl:ENSG00000181449(gene)|ensembl:ENST00000325404(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001649"(osteoblast differentiation)|go:"GO:0001654"(eye development)|go:"GO:0001714"(endodermal cell fate specification)|go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006325"(chromatin organization)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0009611"(response to wounding)|go:"GO:0009653"(anatomical structure morphogenesis)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0021781"(glial cell fate commitment)|go:"GO:0021983"(pituitary gland development)|go:"GO:0021984"(adenohypophysis development)|go:"GO:0022409"(positive regulation of cell-cell adhesion)|go:"GO:0030154"(cell differentiation)|go:"GO:0030900"(forebrain development)|go:"GO:0035019"(somatic stem cell population maintenance)|go:"GO:0035198"(miRNA binding)|go:"GO:0042246"(tissue regeneration)|go:"GO:0043281"(regulation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0043410"(positive regulation of MAPK cascade)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045165"(cell fate commitment)|go:"GO:0045597"(positive regulation of cell differentiation)|go:"GO:0045665"(negative regulation of neuron differentiation)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048839"(inner ear development)|go:"GO:0050680"(negative regulation of epithelial cell proliferation)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0070848"(response to growth factor)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:0097150"(neuronal stem cell population maintenance)|interpro:IPR009071(High mobility group box, HMG)|interpro:IPR022097|interpro:IPR032643|interpro:IPR036910|mint:P48431|rcsb pdb:1O4X|rcsb pdb:2LE4|rcsb pdb:6T7B|rcsb pdb:6T90|rcsb pdb:6WX7|rcsb pdb:6WX8|rcsb pdb:6WX9|rcsb pdb:6YOV|reactome:R-HSA-2892245|reactome:R-HSA-2892247|reactome:R-HSA-3769402|reactome:R-HSA-452723|reactome:R-HSA-6785807|reactome:R-HSA-8986944 ensembl:ENSP00000352400|ensembl:ENST00000411637|ensembl:ENSP00000396576|refseq:NP_005076.3|refseq:NP_001305253.1|refseq:NP_001305254.1|dip:DIP-38367N|rcsb pdb:3FMP|rcsb pdb:5DIS|reactome:R-HSA-1169408|reactome:R-HSA-159227|reactome:R-HSA-159230|reactome:R-HSA-159231|reactome:R-HSA-159236|reactome:R-HSA-165054|reactome:R-HSA-168271|reactome:R-HSA-168276|reactome:R-HSA-168325|reactome:R-HSA-168333|reactome:R-HSA-170822|reactome:R-HSA-180746|reactome:R-HSA-180910|reactome:R-HSA-191859|reactome:R-HSA-3108214|reactome:R-HSA-3232142|reactome:R-HSA-3301854|reactome:R-HSA-3371453|reactome:R-HSA-4085377|reactome:R-HSA-450520|reactome:R-HSA-4551638|reactome:R-HSA-4570464|reactome:R-HSA-4615885|reactome:R-HSA-5578749|reactome:R-HSA-5619107|reactome:R-HSA-6784531|reactome:R-HSA-9609690|reactome:R-HSA-9610379|rcsb pdb:3FMO|ensembl:ENSG00000126883(gene)|ensembl:ENST00000359428(transcript)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0005049"(nuclear export signal receptor activity)|go:"GO:0005643"(nuclear pore)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006405"(RNA export from nucleus)|go:"GO:0006406"(mRNA export from nucleus)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0006611"(protein export from nucleus)|go:"GO:0008139"(nuclear localization sequence binding)|go:"GO:0017056"(structural constituent of nuclear pore)|go:"GO:0046822"(regulation of nucleocytoplasmic transport)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:1990876"(cytoplasmic side of nuclear pore)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR026054|interpro:IPR041553|mint:P35658|rcsb pdb:2OIT|rcsb pdb:3FHC go:"GO:0005634"(nucleus) - - figure legend:ST2 F2A|comment:proteins identified only in our induced samples in three MudPIT analyses with the more stringent BY-adjusted significance p<0.05|dataset:Brain Disease - Neurological Diseases & Disorders|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-daoy)|taxid:9606(Homo sapiens DAOY cerebellar medulloblastoma cell line) - 2020/12/29 2020/12/29 rogid:cn8gYfKDpQc8J2ygnqny32sIyyU9606 rogid:cW7RIiR4uhQgXIaByMiW3niFtTo9606 rigid:6EMs5+B89Q89RCR/2S2BG6PhH9E false tandem tag:n-n - - - psi-mi:"MI:0658"(multidimensional protein identification technology) psi-mi:"MI:0658"(multidimensional protein identification technology) uniprotkb:P48431 uniprotkb:Q9HAV4 intact:EBI-6124081|uniprotkb:Q14537|ensembl:ENSP00000323588 intact:EBI-517949|uniprotkb:Q5JTE6|uniprotkb:Q96G48|uniprotkb:Q96HN3|uniprotkb:Q9BWM6|uniprotkb:Q9BZV5|uniprotkb:Q9H9M4|uniprotkb:Q9NT89|uniprotkb:Q9NW39|uniprotkb:Q9ULC9|ensembl:ENSP00000265351 psi-mi:sox2_human(display_long)|uniprotkb:SOX2(gene name)|psi-mi:SOX2(display_short) psi-mi:xpo5_human(display_long)|uniprotkb:Ran-binding protein 21(gene name synonym)|uniprotkb:XPO5(gene name)|psi-mi:XPO5(display_short)|uniprotkb:KIAA1291(gene name synonym)|uniprotkb:RANBP21(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Cox et al. (2012) pubmed:23667531|imex:IM-28599 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-26574619|imex:IM-28599-5 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_003097.1|dip:DIP-59913N|ensembl:ENSG00000181449(gene)|ensembl:ENST00000325404(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001649"(osteoblast differentiation)|go:"GO:0001654"(eye development)|go:"GO:0001714"(endodermal cell fate specification)|go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006325"(chromatin organization)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0009611"(response to wounding)|go:"GO:0009653"(anatomical structure morphogenesis)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0021781"(glial cell fate commitment)|go:"GO:0021983"(pituitary gland development)|go:"GO:0021984"(adenohypophysis development)|go:"GO:0022409"(positive regulation of cell-cell adhesion)|go:"GO:0030154"(cell differentiation)|go:"GO:0030900"(forebrain development)|go:"GO:0035019"(somatic stem cell population maintenance)|go:"GO:0035198"(miRNA binding)|go:"GO:0042246"(tissue regeneration)|go:"GO:0043281"(regulation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0043410"(positive regulation of MAPK cascade)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045165"(cell fate commitment)|go:"GO:0045597"(positive regulation of cell differentiation)|go:"GO:0045665"(negative regulation of neuron differentiation)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048839"(inner ear development)|go:"GO:0050680"(negative regulation of epithelial cell proliferation)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0070848"(response to growth factor)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:0097150"(neuronal stem cell population maintenance)|interpro:IPR009071(High mobility group box, HMG)|interpro:IPR022097|interpro:IPR032643|interpro:IPR036910|mint:P48431|rcsb pdb:1O4X|rcsb pdb:2LE4|rcsb pdb:6T7B|rcsb pdb:6T90|rcsb pdb:6WX7|rcsb pdb:6WX8|rcsb pdb:6WX9|rcsb pdb:6YOV|reactome:R-HSA-2892245|reactome:R-HSA-2892247|reactome:R-HSA-3769402|reactome:R-HSA-452723|reactome:R-HSA-6785807|reactome:R-HSA-8986944 refseq:NP_065801.1|dip:DIP-34547N|rcsb pdb:5YU7|reactome:R-HSA-203927|ensembl:ENSG00000124571(gene)|ensembl:ENST00000265351(transcript)|go:"GO:0000049"(tRNA binding)|go:"GO:0005049"(nuclear export signal receptor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006405"(RNA export from nucleus)|go:"GO:0006611"(protein export from nucleus)|go:"GO:0010586"(miRNA metabolic process)|go:"GO:0016442"(RISC complex)|go:"GO:0031267"(small GTPase binding)|go:"GO:0035281"(pre-miRNA export from nucleus)|go:"GO:0042565"(RNA nuclear export complex)|go:"GO:0070883"(pre-miRNA binding)|go:"GO:1900370"(positive regulation of RNA interference)|go:"GO:1905172"(RISC complex binding)|interpro:IPR001494(Importin-beta, N-terminal)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR013598(Exportin-1/Importin-beta-like)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR040018|mint:Q9HAV4|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)|rcsb pdb:3A6P|rcsb pdb:5YU6 go:"GO:0005634"(nucleus) - - figure legend:ST2 F2A|comment:proteins identified only in our induced samples in three MudPIT analyses with the more stringent BY-adjusted significance p<0.05|dataset:Brain Disease - Neurological Diseases & Disorders|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-daoy)|taxid:9606(Homo sapiens DAOY cerebellar medulloblastoma cell line) - 2020/12/29 2020/12/29 rogid:cn8gYfKDpQc8J2ygnqny32sIyyU9606 rogid:wuUAxvyCl/u7CRtQLMK9McSoUrM9606 rigid:6EMs5+B89Q89RCR/2S2BG6PhH9E false tandem tag:n-n - - - psi-mi:"MI:0658"(multidimensional protein identification technology) psi-mi:"MI:0658"(multidimensional protein identification technology) uniprotkb:P48431 uniprotkb:Q8TD26 intact:EBI-6124081|uniprotkb:Q14537|ensembl:ENSP00000323588 intact:EBI-1043681|uniprotkb:Q5JYQ0|uniprotkb:Q5TGZ9|uniprotkb:Q5TH00|uniprotkb:Q5TH01|uniprotkb:Q8IZR2|uniprotkb:Q8WTY0|uniprotkb:Q9H4H6|uniprotkb:Q9H6D4|uniprotkb:Q9NTT7|uniprotkb:Q9P2L1|ensembl:ENSP00000362330 psi-mi:sox2_human(display_long)|uniprotkb:SOX2(gene name)|psi-mi:SOX2(display_short) psi-mi:chd6_human(display_long)|uniprotkb:CHD6(gene name)|psi-mi:CHD6(display_short)|uniprotkb:CHD5(gene name synonym)|uniprotkb:KIAA1335(gene name synonym)|uniprotkb:RIGB(gene name synonym)|uniprotkb:ATP-dependent helicase CHD6(gene name synonym)|uniprotkb:Radiation-induced gene B protein(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Cox et al. (2012) pubmed:23667531|imex:IM-28599 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-26574619|imex:IM-28599-5 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_003097.1|dip:DIP-59913N|ensembl:ENSG00000181449(gene)|ensembl:ENST00000325404(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001649"(osteoblast differentiation)|go:"GO:0001654"(eye development)|go:"GO:0001714"(endodermal cell fate specification)|go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006325"(chromatin organization)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0009611"(response to wounding)|go:"GO:0009653"(anatomical structure morphogenesis)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0021781"(glial cell fate commitment)|go:"GO:0021983"(pituitary gland development)|go:"GO:0021984"(adenohypophysis development)|go:"GO:0022409"(positive regulation of cell-cell adhesion)|go:"GO:0030154"(cell differentiation)|go:"GO:0030900"(forebrain development)|go:"GO:0035019"(somatic stem cell population maintenance)|go:"GO:0035198"(miRNA binding)|go:"GO:0042246"(tissue regeneration)|go:"GO:0043281"(regulation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0043410"(positive regulation of MAPK cascade)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045165"(cell fate commitment)|go:"GO:0045597"(positive regulation of cell differentiation)|go:"GO:0045665"(negative regulation of neuron differentiation)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048839"(inner ear development)|go:"GO:0050680"(negative regulation of epithelial cell proliferation)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0070848"(response to growth factor)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:0097150"(neuronal stem cell population maintenance)|interpro:IPR009071(High mobility group box, HMG)|interpro:IPR022097|interpro:IPR032643|interpro:IPR036910|mint:P48431|rcsb pdb:1O4X|rcsb pdb:2LE4|rcsb pdb:6T7B|rcsb pdb:6T90|rcsb pdb:6WX7|rcsb pdb:6WX8|rcsb pdb:6WX9|rcsb pdb:6YOV|reactome:R-HSA-2892245|reactome:R-HSA-2892247|reactome:R-HSA-3769402|reactome:R-HSA-452723|reactome:R-HSA-6785807|reactome:R-HSA-8986944 ensembl:ENSG00000124177(gene)|ensembl:ENST00000373233(transcript)|go:"GO:0036091"(positive regulation of transcription from RNA polymerase II promoter in response to oxidative stress)|go:"GO:0070615"|go:"GO:0140603"(obsolete ATP hydrolysis activity)|interpro:IPR000330(SNF2-related)|go:"GO:0001221"(transcription coregulator binding)|interpro:IPR000953(Chromo domain)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|go:"GO:0003677"(DNA binding)|interpro:IPR002464(DNA/RNA helicase, ATP-dependent, DEAH-box type, conserved site)|interpro:IPR006576(BRK)|interpro:IPR014001(DEAD-like helicase, N-terminal)|go:"GO:0003678"(DNA helicase activity)|interpro:IPR016197(Chromo domain-like)|interpro:IPR023780|interpro:IPR027417|interpro:IPR037259|interpro:IPR038718|mint:Q8TD26|rcsb pdb:2EPB|go:"GO:0005524"(ATP binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006325"(chromatin organization)|go:"GO:0008094"(ATP-dependent activity, acting on DNA)|refseq:NP_115597.3 go:"GO:0005634"(nucleus) - - figure legend:ST2 F2A|comment:proteins identified only in our induced samples in three MudPIT analyses with the more stringent BY-adjusted significance p<0.05|dataset:Brain Disease - Neurological Diseases & Disorders|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-daoy)|taxid:9606(Homo sapiens DAOY cerebellar medulloblastoma cell line) - 2020/12/29 2020/12/29 rogid:cn8gYfKDpQc8J2ygnqny32sIyyU9606 rogid:3OZYCM6IRFVXZHCvEycD2Ha8gKI9606 rigid:6EMs5+B89Q89RCR/2S2BG6PhH9E false tandem tag:n-n - - - psi-mi:"MI:0658"(multidimensional protein identification technology) psi-mi:"MI:0658"(multidimensional protein identification technology) uniprotkb:P48431 uniprotkb:P17655 intact:EBI-6124081|uniprotkb:Q14537|ensembl:ENSP00000323588 intact:EBI-1028956|uniprotkb:Q16738|uniprotkb:Q6PJT3|uniprotkb:Q8WU26|uniprotkb:Q9HBB1|uniprotkb:A6NDG7|ensembl:ENSP00000295006|uniprotkb:B7ZA96|uniprotkb:E7ES58 psi-mi:sox2_human(display_long)|uniprotkb:SOX2(gene name)|psi-mi:SOX2(display_short) psi-mi:can2_human(display_long)|uniprotkb:CAPN2(gene name)|psi-mi:CAPN2(display_short)|uniprotkb:CANPL2(gene name synonym)|uniprotkb:Calpain-2 large subunit(gene name synonym)|uniprotkb:Calcium-activated neutral proteinase 2(gene name synonym)|uniprotkb:Calpain M-type(gene name synonym)|uniprotkb:Millimolar-calpain(gene name synonym)|uniprotkb:Calpain large polypeptide L2(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Cox et al. (2012) pubmed:23667531|imex:IM-28599 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-26574619|imex:IM-28599-5 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_003097.1|dip:DIP-59913N|ensembl:ENSG00000181449(gene)|ensembl:ENST00000325404(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001649"(osteoblast differentiation)|go:"GO:0001654"(eye development)|go:"GO:0001714"(endodermal cell fate specification)|go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006325"(chromatin organization)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0009611"(response to wounding)|go:"GO:0009653"(anatomical structure morphogenesis)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0021781"(glial cell fate commitment)|go:"GO:0021983"(pituitary gland development)|go:"GO:0021984"(adenohypophysis development)|go:"GO:0022409"(positive regulation of cell-cell adhesion)|go:"GO:0030154"(cell differentiation)|go:"GO:0030900"(forebrain development)|go:"GO:0035019"(somatic stem cell population maintenance)|go:"GO:0035198"(miRNA binding)|go:"GO:0042246"(tissue regeneration)|go:"GO:0043281"(regulation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0043410"(positive regulation of MAPK cascade)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045165"(cell fate commitment)|go:"GO:0045597"(positive regulation of cell differentiation)|go:"GO:0045665"(negative regulation of neuron differentiation)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048839"(inner ear development)|go:"GO:0050680"(negative regulation of epithelial cell proliferation)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0070848"(response to growth factor)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:0097150"(neuronal stem cell population maintenance)|interpro:IPR009071(High mobility group box, HMG)|interpro:IPR022097|interpro:IPR032643|interpro:IPR036910|mint:P48431|rcsb pdb:1O4X|rcsb pdb:2LE4|rcsb pdb:6T7B|rcsb pdb:6T90|rcsb pdb:6WX7|rcsb pdb:6WX8|rcsb pdb:6WX9|rcsb pdb:6YOV|reactome:R-HSA-2892245|reactome:R-HSA-2892247|reactome:R-HSA-3769402|reactome:R-HSA-452723|reactome:R-HSA-6785807|reactome:R-HSA-8986944 refseq:NP_001139540.1|refseq:NP_001739.2|ensembl:ENSG00000162909(gene)|ensembl:ENST00000295006(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0001666"(response to hypoxia)|go:"GO:0001824"(blastocyst development)|go:"GO:0004198"(calcium-dependent cysteine-type endopeptidase activity)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005925"(focal adhesion)|go:"GO:0006508"(proteolysis)|go:"GO:0007520"(myoblast fusion)|go:"GO:0007565"(female pregnancy)|go:"GO:0008092"(cytoskeletal protein binding)|go:"GO:0008234"(cysteine-type peptidase activity)|go:"GO:0009897"(external side of plasma membrane)|go:"GO:0010666"(positive regulation of cardiac muscle cell apoptotic process)|go:"GO:0016540"(protein autoprocessing)|go:"GO:0019899"(enzyme binding)|go:"GO:0030425"(dendrite)|go:"GO:0030864"(cortical actin cytoskeleton)|go:"GO:0031143"(pseudopodium)|go:"GO:0032675"(regulation of interleukin-6 production)|go:"GO:0035458"(cellular response to interferon-beta)|go:"GO:0042542"(response to hydrogen peroxide)|go:"GO:0005634"(nucleus)|go:"GO:0043025"(neuronal cell body)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045121"(membrane raft)|go:"GO:0048266"(behavioral response to pain)|go:"GO:0051493"(regulation of cytoskeleton organization)|go:"GO:0051603"(proteolysis involved in cellular protein catabolic process)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071222"(cellular response to lipopolysaccharide)|go:"GO:0071230"(cellular response to amino acid stimulus)|go:"GO:0097038"(perinuclear endoplasmic reticulum)|go:"GO:1901216"(positive regulation of neuron death)|go:"GO:1901741"(positive regulation of myoblast fusion)|go:"GO:2001247"(positive regulation of phosphatidylcholine biosynthetic process)|interpro:IPR000169(Peptidase, cysteine peptidase active site)|interpro:IPR001300(Peptidase C2, calpain)|go:"GO:0005737"(cytoplasm)|go:"GO:0005758"(mitochondrial intermembrane space)|go:"GO:0005764"(lysosome)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005794"(Golgi apparatus)|interpro:IPR011992(EF-Hand type)|interpro:IPR018247|interpro:IPR022682|interpro:IPR022683|interpro:IPR022684|interpro:IPR029539|interpro:IPR033883|interpro:IPR036213|interpro:IPR038765|interpro:IPR042736|mint:P17655|rcsb pdb:1KFU|rcsb pdb:1KFX|rcsb pdb:2NQA|reactome:R-HSA-1474228|reactome:R-HSA-8862803|interpro:IPR002048(Calcium-binding EF-hand) go:"GO:0005634"(nucleus) - - figure legend:ST2 F2A|comment:proteins identified only in our induced samples in three MudPIT analyses with the more stringent BY-adjusted significance p<0.05|dataset:Brain Disease - Neurological Diseases & Disorders|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-daoy)|taxid:9606(Homo sapiens DAOY cerebellar medulloblastoma cell line) - 2020/12/29 2020/12/29 rogid:cn8gYfKDpQc8J2ygnqny32sIyyU9606 rogid:r60XX66kihGVLaa9888soeXjc0M9606 rigid:6EMs5+B89Q89RCR/2S2BG6PhH9E false tandem tag:n-n - - - psi-mi:"MI:0658"(multidimensional protein identification technology) psi-mi:"MI:0658"(multidimensional protein identification technology) uniprotkb:P48431 uniprotkb:O15516 intact:EBI-6124081|uniprotkb:Q14537|ensembl:ENSP00000323588 intact:EBI-1794265|uniprotkb:A0AV01|uniprotkb:O14516|uniprotkb:Q9UIT8|uniprotkb:A2I2N9|ensembl:ENSP00000308741|ensembl:ENSP00000370723|ensembl:ENSP00000426983 psi-mi:sox2_human(display_long)|uniprotkb:SOX2(gene name)|psi-mi:SOX2(display_short) psi-mi:clock_human(display_long)|uniprotkb:CLOCK(gene name)|psi-mi:CLOCK(display_short)|uniprotkb:KIAA0334(gene name synonym)|uniprotkb:BHLHE8(gene name synonym)|uniprotkb:Class E basic helix-loop-helix protein 8(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Cox et al. (2012) pubmed:23667531|imex:IM-28599 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-26574619|imex:IM-28599-5 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_003097.1|dip:DIP-59913N|ensembl:ENSG00000181449(gene)|ensembl:ENST00000325404(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001649"(osteoblast differentiation)|go:"GO:0001654"(eye development)|go:"GO:0001714"(endodermal cell fate specification)|go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006325"(chromatin organization)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0009611"(response to wounding)|go:"GO:0009653"(anatomical structure morphogenesis)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0021781"(glial cell fate commitment)|go:"GO:0021983"(pituitary gland development)|go:"GO:0021984"(adenohypophysis development)|go:"GO:0022409"(positive regulation of cell-cell adhesion)|go:"GO:0030154"(cell differentiation)|go:"GO:0030900"(forebrain development)|go:"GO:0035019"(somatic stem cell population maintenance)|go:"GO:0035198"(miRNA binding)|go:"GO:0042246"(tissue regeneration)|go:"GO:0043281"(regulation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0043410"(positive regulation of MAPK cascade)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045165"(cell fate commitment)|go:"GO:0045597"(positive regulation of cell differentiation)|go:"GO:0045665"(negative regulation of neuron differentiation)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048839"(inner ear development)|go:"GO:0050680"(negative regulation of epithelial cell proliferation)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0070848"(response to growth factor)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:0097150"(neuronal stem cell population maintenance)|interpro:IPR009071(High mobility group box, HMG)|interpro:IPR022097|interpro:IPR032643|interpro:IPR036910|mint:P48431|rcsb pdb:1O4X|rcsb pdb:2LE4|rcsb pdb:6T7B|rcsb pdb:6T90|rcsb pdb:6WX7|rcsb pdb:6WX8|rcsb pdb:6WX9|rcsb pdb:6YOV|reactome:R-HSA-2892245|reactome:R-HSA-2892247|reactome:R-HSA-3769402|reactome:R-HSA-452723|reactome:R-HSA-6785807|reactome:R-HSA-8986944 refseq:XP_011532711.1|refseq:XP_011532712.1|refseq:XP_011532713.1|refseq:NP_004889.1|refseq:XP_016864343.1|refseq:NP_001254772.1|refseq:XP_005265844.1|dip:DIP-46009N|ensembl:ENSG00000134852(gene)|ensembl:ENST00000309964(transcript)|ensembl:ENST00000381322(transcript)|ensembl:ENST00000513440(transcript)|go:"GO:0000077"(DNA damage checkpoint signaling)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0004402"(histone acetyltransferase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005694"(chromosome)|go:"GO:0005829"(cytosol)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006473"(protein acetylation)|go:"GO:0007165"(signal transduction)|go:"GO:0007283"(spermatogenesis)|go:"GO:0007623"(circadian rhythm)|go:"GO:0009648"(photoperiodism)|go:"GO:0031490"(chromatin DNA binding)|go:"GO:0032922"(circadian regulation of gene expression)|go:"GO:0033391"(chromatoid body)|go:"GO:0042634"(regulation of hair cycle)|go:"GO:0042752"(regulation of circadian rhythm)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046983"(protein dimerization activity)|go:"GO:0050729"(positive regulation of inflammatory response)|go:"GO:0050796"(regulation of insulin secretion)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|go:"GO:0051775"(response to redox state)|go:"GO:0070888"(E-box binding)|go:"GO:0071479"(cellular response to ionizing radiation)|go:"GO:1990513"(CLOCK-BMAL transcription complex)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|go:"GO:2000074"(regulation of type B pancreatic cell development)|go:"GO:2000323"(negative regulation of glucocorticoid receptor signaling pathway)|interpro:IPR000014(PAS)|interpro:IPR001067(Nuclear translocator)|interpro:IPR001610(PAC motif)|interpro:IPR011598(Helix-loop-helix DNA-binding)|interpro:IPR013767(PAS fold)|interpro:IPR035965|interpro:IPR036638|mint:O15516|rcsb pdb:4H10|rcsb pdb:6QPJ|reactome:R-HSA-1368108|reactome:R-HSA-1989781|reactome:R-HSA-3214847|reactome:R-HSA-400253|reactome:R-HSA-9707616 go:"GO:0005634"(nucleus) - - figure legend:ST2 F2A|comment:proteins identified only in our induced samples in three MudPIT analyses with the more stringent BY-adjusted significance p<0.05|dataset:Brain Disease - Neurological Diseases & Disorders|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-daoy)|taxid:9606(Homo sapiens DAOY cerebellar medulloblastoma cell line) - 2020/12/29 2020/12/29 rogid:cn8gYfKDpQc8J2ygnqny32sIyyU9606 rogid:bnvElV5HCTAAT1rItDfxE6zoY/M9606 rigid:6EMs5+B89Q89RCR/2S2BG6PhH9E false tandem tag:n-n - - - psi-mi:"MI:0658"(multidimensional protein identification technology) psi-mi:"MI:0658"(multidimensional protein identification technology) uniprotkb:P48431 uniprotkb:O15062 intact:EBI-6124081|uniprotkb:Q14537|ensembl:ENSP00000323588 intact:EBI-722671|ensembl:ENSP00000307604 psi-mi:sox2_human(display_long)|uniprotkb:SOX2(gene name)|psi-mi:SOX2(display_short) psi-mi:zbtb5_human(display_long)|uniprotkb:ZBTB5(gene name)|psi-mi:ZBTB5(display_short)|uniprotkb:KIAA0354(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Cox et al. (2012) pubmed:23667531|imex:IM-28599 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-26574619|imex:IM-28599-5 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_003097.1|dip:DIP-59913N|ensembl:ENSG00000181449(gene)|ensembl:ENST00000325404(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001649"(osteoblast differentiation)|go:"GO:0001654"(eye development)|go:"GO:0001714"(endodermal cell fate specification)|go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006325"(chromatin organization)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0009611"(response to wounding)|go:"GO:0009653"(anatomical structure morphogenesis)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0021781"(glial cell fate commitment)|go:"GO:0021983"(pituitary gland development)|go:"GO:0021984"(adenohypophysis development)|go:"GO:0022409"(positive regulation of cell-cell adhesion)|go:"GO:0030154"(cell differentiation)|go:"GO:0030900"(forebrain development)|go:"GO:0035019"(somatic stem cell population maintenance)|go:"GO:0035198"(miRNA binding)|go:"GO:0042246"(tissue regeneration)|go:"GO:0043281"(regulation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0043410"(positive regulation of MAPK cascade)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045165"(cell fate commitment)|go:"GO:0045597"(positive regulation of cell differentiation)|go:"GO:0045665"(negative regulation of neuron differentiation)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048839"(inner ear development)|go:"GO:0050680"(negative regulation of epithelial cell proliferation)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0070848"(response to growth factor)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:0097150"(neuronal stem cell population maintenance)|interpro:IPR009071(High mobility group box, HMG)|interpro:IPR022097|interpro:IPR032643|interpro:IPR036910|mint:P48431|rcsb pdb:1O4X|rcsb pdb:2LE4|rcsb pdb:6T7B|rcsb pdb:6T90|rcsb pdb:6WX7|rcsb pdb:6WX8|rcsb pdb:6WX9|rcsb pdb:6YOV|reactome:R-HSA-2892245|reactome:R-HSA-2892247|reactome:R-HSA-3769402|reactome:R-HSA-452723|reactome:R-HSA-6785807|reactome:R-HSA-8986944 refseq:NP_055687.1|refseq:XP_005251691.1|dip:DIP-41566N|ensembl:ENSG00000168795(gene)|ensembl:ENST00000307750(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|interpro:IPR000210(BTB/POZ-like)|interpro:IPR011333(BTB/POZ fold)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR036236|mint:O15062 go:"GO:0005634"(nucleus) - - figure legend:ST2 F2A|comment:proteins identified only in our induced samples in three MudPIT analyses with the more stringent BY-adjusted significance p<0.05|dataset:Brain Disease - Neurological Diseases & Disorders|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-daoy)|taxid:9606(Homo sapiens DAOY cerebellar medulloblastoma cell line) - 2020/12/29 2020/12/29 rogid:cn8gYfKDpQc8J2ygnqny32sIyyU9606 rogid:snw/pD42fIJp5zlezPU76fP1jZc9606 rigid:6EMs5+B89Q89RCR/2S2BG6PhH9E false tandem tag:n-n - - - psi-mi:"MI:0658"(multidimensional protein identification technology) psi-mi:"MI:0658"(multidimensional protein identification technology) uniprotkb:P48431 uniprotkb:Q641Q2 intact:EBI-6124081|uniprotkb:Q14537|ensembl:ENSP00000323588 intact:EBI-2870155|intact:EBI-4401456|uniprotkb:A2A3S2|uniprotkb:A2A3U6|uniprotkb:Q5SNT6|uniprotkb:Q6DHY0|intact:EBI-28969894|ensembl:ENSP00000282633 psi-mi:sox2_human(display_long)|uniprotkb:SOX2(gene name)|psi-mi:SOX2(display_short) psi-mi:wac2a_human(display_long)|uniprotkb:WASHC2A(gene name)|psi-mi:WASHC2A(display_short)|uniprotkb:FAM21A(gene name synonym)|uniprotkb:FAM21B(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Cox et al. (2012) pubmed:23667531|imex:IM-28599 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-26574619|imex:IM-28599-5 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_003097.1|dip:DIP-59913N|ensembl:ENSG00000181449(gene)|ensembl:ENST00000325404(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001649"(osteoblast differentiation)|go:"GO:0001654"(eye development)|go:"GO:0001714"(endodermal cell fate specification)|go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006325"(chromatin organization)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0009611"(response to wounding)|go:"GO:0009653"(anatomical structure morphogenesis)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0021781"(glial cell fate commitment)|go:"GO:0021983"(pituitary gland development)|go:"GO:0021984"(adenohypophysis development)|go:"GO:0022409"(positive regulation of cell-cell adhesion)|go:"GO:0030154"(cell differentiation)|go:"GO:0030900"(forebrain development)|go:"GO:0035019"(somatic stem cell population maintenance)|go:"GO:0035198"(miRNA binding)|go:"GO:0042246"(tissue regeneration)|go:"GO:0043281"(regulation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0043410"(positive regulation of MAPK cascade)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045165"(cell fate commitment)|go:"GO:0045597"(positive regulation of cell differentiation)|go:"GO:0045665"(negative regulation of neuron differentiation)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048839"(inner ear development)|go:"GO:0050680"(negative regulation of epithelial cell proliferation)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0070848"(response to growth factor)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:0097150"(neuronal stem cell population maintenance)|interpro:IPR009071(High mobility group box, HMG)|interpro:IPR022097|interpro:IPR032643|interpro:IPR036910|mint:P48431|rcsb pdb:1O4X|rcsb pdb:2LE4|rcsb pdb:6T7B|rcsb pdb:6T90|rcsb pdb:6WX7|rcsb pdb:6WX8|rcsb pdb:6WX9|rcsb pdb:6YOV|reactome:R-HSA-2892245|reactome:R-HSA-2892247|reactome:R-HSA-3769402|reactome:R-HSA-452723|reactome:R-HSA-6785807|reactome:R-HSA-8986944 ensembl:ENSP00000282633|ensembl:ENST00000351071|ensembl:ENSP00000344037|refseq:NP_001005751.1|refseq:NP_001278327.1|ensembl:ENSG00000099290(gene)|ensembl:ENST00000282633(transcript)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0008289"(lipid binding)|go:"GO:0015031"(protein transport)|go:"GO:0031901"(early endosome membrane)|go:"GO:0036010"(protein localization to endosome)|go:"GO:0042147"(retrograde transport, endosome to Golgi)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0071203"(WASH complex)|interpro:IPR029341|mint:Q641Q2|go:"GO:0005769"(early endosome) go:"GO:0005634"(nucleus) - - figure legend:ST2 F2A|comment:proteins identified only in our induced samples in three MudPIT analyses with the more stringent BY-adjusted significance p<0.05|dataset:Brain Disease - Neurological Diseases & Disorders|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-daoy)|taxid:9606(Homo sapiens DAOY cerebellar medulloblastoma cell line) - 2020/12/29 2020/12/29 rogid:cn8gYfKDpQc8J2ygnqny32sIyyU9606 rogid:JtzABQxJJmBcNqKPsm/t5KJa2Lw9606 rigid:6EMs5+B89Q89RCR/2S2BG6PhH9E false tandem tag:n-n - - - psi-mi:"MI:0658"(multidimensional protein identification technology) psi-mi:"MI:0658"(multidimensional protein identification technology) uniprotkb:P48431 uniprotkb:Q13362 intact:EBI-6124081|uniprotkb:Q14537|ensembl:ENSP00000323588 intact:EBI-1266156|uniprotkb:B4DYJ8|uniprotkb:F5GWP3|uniprotkb:Q14391|uniprotkb:Q15060|uniprotkb:Q15174|uniprotkb:B5BUA5|intact:EBI-2556020|uniprotkb:Q6ZN33|ensembl:ENSP00000333905 psi-mi:sox2_human(display_long)|uniprotkb:SOX2(gene name)|psi-mi:SOX2(display_short) psi-mi:2a5g_human(display_long)|uniprotkb:PPP2R5C(gene name)|psi-mi:PPP2R5C(display_short)|uniprotkb:KIAA0044(gene name synonym)|uniprotkb:PP2A B subunit isoform B'-gamma(gene name synonym)|uniprotkb:PP2A B subunit isoform B56-gamma(gene name synonym)|uniprotkb:PP2A B subunit isoform PR61-gamma(gene name synonym)|uniprotkb:PP2A B subunit isoform R5-gamma(gene name synonym)|uniprotkb:Renal carcinoma antigen NY-REN-29(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Cox et al. (2012) pubmed:23667531|imex:IM-28599 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-26574619|imex:IM-28599-5 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_003097.1|dip:DIP-59913N|ensembl:ENSG00000181449(gene)|ensembl:ENST00000325404(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001649"(osteoblast differentiation)|go:"GO:0001654"(eye development)|go:"GO:0001714"(endodermal cell fate specification)|go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006325"(chromatin organization)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0009611"(response to wounding)|go:"GO:0009653"(anatomical structure morphogenesis)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0021781"(glial cell fate commitment)|go:"GO:0021983"(pituitary gland development)|go:"GO:0021984"(adenohypophysis development)|go:"GO:0022409"(positive regulation of cell-cell adhesion)|go:"GO:0030154"(cell differentiation)|go:"GO:0030900"(forebrain development)|go:"GO:0035019"(somatic stem cell population maintenance)|go:"GO:0035198"(miRNA binding)|go:"GO:0042246"(tissue regeneration)|go:"GO:0043281"(regulation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0043410"(positive regulation of MAPK cascade)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045165"(cell fate commitment)|go:"GO:0045597"(positive regulation of cell differentiation)|go:"GO:0045665"(negative regulation of neuron differentiation)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048839"(inner ear development)|go:"GO:0050680"(negative regulation of epithelial cell proliferation)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0070848"(response to growth factor)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:0097150"(neuronal stem cell population maintenance)|interpro:IPR009071(High mobility group box, HMG)|interpro:IPR022097|interpro:IPR032643|interpro:IPR036910|mint:P48431|rcsb pdb:1O4X|rcsb pdb:2LE4|rcsb pdb:6T7B|rcsb pdb:6T90|rcsb pdb:6WX7|rcsb pdb:6WX8|rcsb pdb:6WX9|rcsb pdb:6YOV|reactome:R-HSA-2892245|reactome:R-HSA-2892247|reactome:R-HSA-3769402|reactome:R-HSA-452723|reactome:R-HSA-6785807|reactome:R-HSA-8986944 refseq:NP_002710.2|refseq:NP_848701.1|refseq:NP_848702.1|refseq:NP_001155197.1|refseq:NP_001155198.1|refseq:XP_011535222.1|refseq:XP_005267884.1|dip:DIP-39401N|ensembl:ENSG00000078304(gene)|ensembl:ENST00000334743(transcript)|go:"GO:0000159"(protein phosphatase type 2A complex)|go:"GO:0000775"(chromosome, centromeric region)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0006470"(protein dephosphorylation)|go:"GO:0006977"(DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest)|go:"GO:0007165"(signal transduction)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0019888"(protein phosphatase regulator activity)|go:"GO:0031952"(regulation of protein autophosphorylation)|go:"GO:0042771"(intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0072542"(protein phosphatase activator activity)|interpro:IPR002554(Protein phosphatase 2A, regulatory B subunit, B56)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|mint:Q13362|rcsb pdb:2IAE|rcsb pdb:2JAK|rcsb pdb:2NPP|rcsb pdb:2NYL|rcsb pdb:2NYM|rcsb pdb:3FGA|rcsb pdb:5JJA|rcsb pdb:5K6S|rcsb pdb:5SW9|rcsb pdb:5SWF|rcsb pdb:6OYL|rcsb pdb:6TOQ|rcsb pdb:6VOY|rcsb pdb:6VRO|rcsb pdb:6Z2Y|reactome:R-HSA-195253|reactome:R-HSA-196299|reactome:R-HSA-2467813|reactome:R-HSA-2500257|reactome:R-HSA-389513|reactome:R-HSA-432142|reactome:R-HSA-4641262|reactome:R-HSA-5339716|reactome:R-HSA-5358747|reactome:R-HSA-5358749|reactome:R-HSA-5358751|reactome:R-HSA-5358752|reactome:R-HSA-5467337|reactome:R-HSA-141444|reactome:R-HSA-5467340|reactome:R-HSA-5467348|reactome:R-HSA-5663220|reactome:R-HSA-5673000|reactome:R-HSA-5675221|reactome:R-HSA-6804757|reactome:R-HSA-6811558|reactome:R-HSA-68877|reactome:R-HSA-9648025 go:"GO:0005634"(nucleus) - - figure legend:ST2 F2A|comment:proteins identified only in our induced samples in three MudPIT analyses with the more stringent BY-adjusted significance p<0.05|dataset:Brain Disease - Neurological Diseases & Disorders|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-daoy)|taxid:9606(Homo sapiens DAOY cerebellar medulloblastoma cell line) - 2020/12/29 2020/12/29 rogid:cn8gYfKDpQc8J2ygnqny32sIyyU9606 rogid:vKPPLnEfyCzEZ2O5lrQDCRghiV09606 rigid:6EMs5+B89Q89RCR/2S2BG6PhH9E false tandem tag:n-n - - - psi-mi:"MI:0658"(multidimensional protein identification technology) psi-mi:"MI:0658"(multidimensional protein identification technology) uniprotkb:P48431 uniprotkb:Q13112 intact:EBI-6124081|uniprotkb:Q14537|ensembl:ENSP00000323588 intact:EBI-1052944|uniprotkb:Q99548|ensembl:ENSP00000315700 psi-mi:sox2_human(display_long)|uniprotkb:SOX2(gene name)|psi-mi:SOX2(display_short) psi-mi:caf1b_human(display_long)|uniprotkb:Chromatin assembly factor I p60 subunit(gene name synonym)|uniprotkb:M-phase phosphoprotein 7(gene name synonym)|uniprotkb:CHAF1B(gene name)|psi-mi:CHAF1B(display_short)|uniprotkb:CAF1A(gene name synonym)|uniprotkb:CAF1P60(gene name synonym)|uniprotkb:MPHOSPH7(gene name synonym)|uniprotkb:MPP7(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Cox et al. (2012) pubmed:23667531|imex:IM-28599 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-26574619|imex:IM-28599-5 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_003097.1|dip:DIP-59913N|ensembl:ENSG00000181449(gene)|ensembl:ENST00000325404(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001649"(osteoblast differentiation)|go:"GO:0001654"(eye development)|go:"GO:0001714"(endodermal cell fate specification)|go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006325"(chromatin organization)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0009611"(response to wounding)|go:"GO:0009653"(anatomical structure morphogenesis)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0021781"(glial cell fate commitment)|go:"GO:0021983"(pituitary gland development)|go:"GO:0021984"(adenohypophysis development)|go:"GO:0022409"(positive regulation of cell-cell adhesion)|go:"GO:0030154"(cell differentiation)|go:"GO:0030900"(forebrain development)|go:"GO:0035019"(somatic stem cell population maintenance)|go:"GO:0035198"(miRNA binding)|go:"GO:0042246"(tissue regeneration)|go:"GO:0043281"(regulation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0043410"(positive regulation of MAPK cascade)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045165"(cell fate commitment)|go:"GO:0045597"(positive regulation of cell differentiation)|go:"GO:0045665"(negative regulation of neuron differentiation)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048839"(inner ear development)|go:"GO:0050680"(negative regulation of epithelial cell proliferation)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0070848"(response to growth factor)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:0097150"(neuronal stem cell population maintenance)|interpro:IPR009071(High mobility group box, HMG)|interpro:IPR022097|interpro:IPR032643|interpro:IPR036910|mint:P48431|rcsb pdb:1O4X|rcsb pdb:2LE4|rcsb pdb:6T7B|rcsb pdb:6T90|rcsb pdb:6WX7|rcsb pdb:6WX8|rcsb pdb:6WX9|rcsb pdb:6YOV|reactome:R-HSA-2892245|reactome:R-HSA-2892247|reactome:R-HSA-3769402|reactome:R-HSA-452723|reactome:R-HSA-6785807|reactome:R-HSA-8986944 refseq:NP_005432.1|dip:DIP-29243N|ensembl:ENSG00000159259(gene)|ensembl:ENST00000314103(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006260"(DNA replication)|go:"GO:0006281"(DNA repair)|go:"GO:0006334"(nucleosome assembly)|go:"GO:0006335"(DNA replication-dependent chromatin assembly)|go:"GO:0007049"(cell cycle)|go:"GO:0031497"(chromatin assembly)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033186"(CAF-1 complex)|go:"GO:0042393"(histone binding)|go:"GO:0051082"(unfolded protein binding)|interpro:IPR001632(G-protein, beta subunit)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019775|interpro:IPR029129|interpro:IPR036322|mint:Q13112|refseq:XP_016883966.1|refseq:XP_016883967.1 go:"GO:0005634"(nucleus) - - figure legend:ST2 F2A|comment:proteins identified only in our induced samples in three MudPIT analyses with the more stringent BY-adjusted significance p<0.05|dataset:Brain Disease - Neurological Diseases & Disorders|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-daoy)|taxid:9606(Homo sapiens DAOY cerebellar medulloblastoma cell line) - 2020/12/29 2020/12/29 rogid:cn8gYfKDpQc8J2ygnqny32sIyyU9606 rogid:VVbW9mpUGYMRPxvlEk9FERHIsJs9606 rigid:6EMs5+B89Q89RCR/2S2BG6PhH9E false tandem tag:n-n - - - psi-mi:"MI:0658"(multidimensional protein identification technology) psi-mi:"MI:0658"(multidimensional protein identification technology) uniprotkb:P48431 uniprotkb:Q9BVJ6 intact:EBI-6124081|uniprotkb:Q14537|ensembl:ENSP00000323588 intact:EBI-473284|uniprotkb:B4DQ08|uniprotkb:E9PEL7|uniprotkb:Q5JYF1|uniprotkb:A8MVQ1|uniprotkb:A8K7A3|ensembl:ENSP00000377944 psi-mi:sox2_human(display_long)|uniprotkb:SOX2(gene name)|psi-mi:SOX2(display_short) psi-mi:ut14a_human(display_long)|uniprotkb:Serologically defined colon cancer antigen 16(gene name synonym)|uniprotkb:Antigen NY-CO-16(gene name synonym)|uniprotkb:UTP14A(gene name)|psi-mi:UTP14A(display_short)|uniprotkb:SDCCAG16(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Cox et al. (2012) pubmed:23667531|imex:IM-28599 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-26574619|imex:IM-28599-5 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_003097.1|dip:DIP-59913N|ensembl:ENSG00000181449(gene)|ensembl:ENST00000325404(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001649"(osteoblast differentiation)|go:"GO:0001654"(eye development)|go:"GO:0001714"(endodermal cell fate specification)|go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006325"(chromatin organization)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0009611"(response to wounding)|go:"GO:0009653"(anatomical structure morphogenesis)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0021781"(glial cell fate commitment)|go:"GO:0021983"(pituitary gland development)|go:"GO:0021984"(adenohypophysis development)|go:"GO:0022409"(positive regulation of cell-cell adhesion)|go:"GO:0030154"(cell differentiation)|go:"GO:0030900"(forebrain development)|go:"GO:0035019"(somatic stem cell population maintenance)|go:"GO:0035198"(miRNA binding)|go:"GO:0042246"(tissue regeneration)|go:"GO:0043281"(regulation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0043410"(positive regulation of MAPK cascade)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045165"(cell fate commitment)|go:"GO:0045597"(positive regulation of cell differentiation)|go:"GO:0045665"(negative regulation of neuron differentiation)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048839"(inner ear development)|go:"GO:0050680"(negative regulation of epithelial cell proliferation)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0070848"(response to growth factor)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:0097150"(neuronal stem cell population maintenance)|interpro:IPR009071(High mobility group box, HMG)|interpro:IPR022097|interpro:IPR032643|interpro:IPR036910|mint:P48431|rcsb pdb:1O4X|rcsb pdb:2LE4|rcsb pdb:6T7B|rcsb pdb:6T90|rcsb pdb:6WX7|rcsb pdb:6WX8|rcsb pdb:6WX9|rcsb pdb:6YOV|reactome:R-HSA-2892245|reactome:R-HSA-2892247|reactome:R-HSA-3769402|reactome:R-HSA-452723|reactome:R-HSA-6785807|reactome:R-HSA-8986944 ensembl:ENSG00000156697(gene)|ensembl:ENST00000394422(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0006364"(rRNA processing)|go:"GO:0032040"(small-subunit processome)|interpro:IPR006709(Small-subunit processome, Utp14)|mint:Q9BVJ6|reactome:R-HSA-6790901|reactome:R-HSA-6791226|refseq:NP_001159693.1|refseq:NP_006640.2|dip:DIP-32505N go:"GO:0005634"(nucleus) - - figure legend:ST2 F2A|comment:proteins identified only in our induced samples in three MudPIT analyses with the more stringent BY-adjusted significance p<0.05|dataset:Brain Disease - Neurological Diseases & Disorders|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-daoy)|taxid:9606(Homo sapiens DAOY cerebellar medulloblastoma cell line) - 2020/12/29 2020/12/29 rogid:cn8gYfKDpQc8J2ygnqny32sIyyU9606 rogid:vBBHvYYgh4LYP335ktHlQ77Dkfc9606 rigid:6EMs5+B89Q89RCR/2S2BG6PhH9E false tandem tag:n-n - - - psi-mi:"MI:0658"(multidimensional protein identification technology) psi-mi:"MI:0658"(multidimensional protein identification technology) uniprotkb:P48431 uniprotkb:Q9Y6J9 intact:EBI-6124081|uniprotkb:Q14537|ensembl:ENSP00000323588 intact:EBI-743984|uniprotkb:Q96HA6|uniprotkb:B2RAT0|ensembl:ENSP00000294168 psi-mi:sox2_human(display_long)|uniprotkb:SOX2(gene name)|psi-mi:SOX2(display_short) psi-mi:taf6l_human(display_long)|uniprotkb:PCAF-associated factor 65-alpha(gene name synonym)|uniprotkb:TAF6L(gene name)|psi-mi:TAF6L(display_short)|uniprotkb:PAF65A(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Cox et al. (2012) pubmed:23667531|imex:IM-28599 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-26574619|imex:IM-28599-5 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_003097.1|dip:DIP-59913N|ensembl:ENSG00000181449(gene)|ensembl:ENST00000325404(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001649"(osteoblast differentiation)|go:"GO:0001654"(eye development)|go:"GO:0001714"(endodermal cell fate specification)|go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006325"(chromatin organization)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0009611"(response to wounding)|go:"GO:0009653"(anatomical structure morphogenesis)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0021781"(glial cell fate commitment)|go:"GO:0021983"(pituitary gland development)|go:"GO:0021984"(adenohypophysis development)|go:"GO:0022409"(positive regulation of cell-cell adhesion)|go:"GO:0030154"(cell differentiation)|go:"GO:0030900"(forebrain development)|go:"GO:0035019"(somatic stem cell population maintenance)|go:"GO:0035198"(miRNA binding)|go:"GO:0042246"(tissue regeneration)|go:"GO:0043281"(regulation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0043410"(positive regulation of MAPK cascade)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045165"(cell fate commitment)|go:"GO:0045597"(positive regulation of cell differentiation)|go:"GO:0045665"(negative regulation of neuron differentiation)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048839"(inner ear development)|go:"GO:0050680"(negative regulation of epithelial cell proliferation)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0070848"(response to growth factor)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:0097150"(neuronal stem cell population maintenance)|interpro:IPR009071(High mobility group box, HMG)|interpro:IPR022097|interpro:IPR032643|interpro:IPR036910|mint:P48431|rcsb pdb:1O4X|rcsb pdb:2LE4|rcsb pdb:6T7B|rcsb pdb:6T90|rcsb pdb:6WX7|rcsb pdb:6WX8|rcsb pdb:6WX9|rcsb pdb:6YOV|reactome:R-HSA-2892245|reactome:R-HSA-2892247|reactome:R-HSA-3769402|reactome:R-HSA-452723|reactome:R-HSA-6785807|reactome:R-HSA-8986944 refseq:NP_006464.1|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006367"(transcription initiation from RNA polymerase II promoter)|go:"GO:0016251"(RNA polymerase II general transcription initiation factor activity)|go:"GO:0016573"(histone acetylation)|go:"GO:0030914"|go:"GO:0043966"(histone H3 acetylation)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046695"("SLIK (SAGA-like) complex")|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0070062"(extracellular exosome)|go:"GO:1904672"(regulation of somatic stem cell population maintenance)|interpro:IPR004823("TATA box binding protein associated factor (TAF)")|interpro:IPR009072(Histone-fold)|interpro:IPR011442(Protein of unknown function DUF1546)|interpro:IPR037796|mint:Q9Y6J9|reactome:R-HSA-3214847|ensembl:ENSG00000162227(gene)|ensembl:ENST00000294168(transcript)|go:"GO:0000118"(histone deacetylase complex)|go:"GO:0000124"(SAGA complex)|go:"GO:0003677"(DNA binding)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005669"(transcription factor TFIID complex)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0006355"(regulation of transcription, DNA-templated) go:"GO:0005634"(nucleus) - - figure legend:ST2 F2A|comment:proteins identified only in our induced samples in three MudPIT analyses with the more stringent BY-adjusted significance p<0.05|dataset:Brain Disease - Neurological Diseases & Disorders|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-daoy)|taxid:9606(Homo sapiens DAOY cerebellar medulloblastoma cell line) - 2020/12/29 2020/12/29 rogid:cn8gYfKDpQc8J2ygnqny32sIyyU9606 rogid:ZcrK24blWTsAkCgruDbSiUflbtA9606 rigid:6EMs5+B89Q89RCR/2S2BG6PhH9E false tandem tag:n-n - - - psi-mi:"MI:0658"(multidimensional protein identification technology) psi-mi:"MI:0658"(multidimensional protein identification technology) uniprotkb:P48431 uniprotkb:Q6P3W7 intact:EBI-6124081|uniprotkb:Q14537|ensembl:ENSP00000323588 intact:EBI-1046810|uniprotkb:Q96EF4|uniprotkb:Q96ST4|uniprotkb:Q9H7V5|uniprotkb:Q9NVH3|uniprotkb:Q9P2I7|ensembl:ENSP00000354061|uniprotkb:A8KAB5 psi-mi:sox2_human(display_long)|uniprotkb:SOX2(gene name)|psi-mi:SOX2(display_short) psi-mi:scyl2_human(display_long)|uniprotkb:Coated vesicle-associated kinase of 104 kDa(gene name synonym)|uniprotkb:SCYL2(gene name)|psi-mi:SCYL2(display_short)|uniprotkb:CVAK104(gene name synonym)|uniprotkb:KIAA1360(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Cox et al. (2012) pubmed:23667531|imex:IM-28599 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-26574619|imex:IM-28599-5 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_003097.1|dip:DIP-59913N|ensembl:ENSG00000181449(gene)|ensembl:ENST00000325404(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001649"(osteoblast differentiation)|go:"GO:0001654"(eye development)|go:"GO:0001714"(endodermal cell fate specification)|go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006325"(chromatin organization)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0009611"(response to wounding)|go:"GO:0009653"(anatomical structure morphogenesis)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0021781"(glial cell fate commitment)|go:"GO:0021983"(pituitary gland development)|go:"GO:0021984"(adenohypophysis development)|go:"GO:0022409"(positive regulation of cell-cell adhesion)|go:"GO:0030154"(cell differentiation)|go:"GO:0030900"(forebrain development)|go:"GO:0035019"(somatic stem cell population maintenance)|go:"GO:0035198"(miRNA binding)|go:"GO:0042246"(tissue regeneration)|go:"GO:0043281"(regulation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0043410"(positive regulation of MAPK cascade)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045165"(cell fate commitment)|go:"GO:0045597"(positive regulation of cell differentiation)|go:"GO:0045665"(negative regulation of neuron differentiation)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048839"(inner ear development)|go:"GO:0050680"(negative regulation of epithelial cell proliferation)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0070848"(response to growth factor)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:0097150"(neuronal stem cell population maintenance)|interpro:IPR009071(High mobility group box, HMG)|interpro:IPR022097|interpro:IPR032643|interpro:IPR036910|mint:P48431|rcsb pdb:1O4X|rcsb pdb:2LE4|rcsb pdb:6T7B|rcsb pdb:6T90|rcsb pdb:6WX7|rcsb pdb:6WX8|rcsb pdb:6WX9|rcsb pdb:6YOV|reactome:R-HSA-2892245|reactome:R-HSA-2892247|reactome:R-HSA-3769402|reactome:R-HSA-452723|reactome:R-HSA-6785807|reactome:R-HSA-8986944 refseq:NP_060458.3|ensembl:ENSG00000136021(gene)|ensembl:ENST00000360820(transcript)|go:"GO:0002092"(positive regulation of receptor internalization)|go:"GO:0004672"(protein kinase activity)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0007420"(brain development)|go:"GO:0008333"(endosome to lysosome transport)|go:"GO:0010008"(endosome membrane)|go:"GO:0021860"(pyramidal neuron development)|go:"GO:0030136"(clathrin-coated vesicle)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:2000286"(receptor internalization involved in canonical Wnt signaling pathway)|go:"GO:2000370"(positive regulation of clathrin-dependent endocytosis)|interpro:IPR000719(Protein kinase, core)|interpro:IPR011009(Protein kinase-like)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|mint:Q6P3W7|refseq:NP_001304713.1|refseq:NP_001317182.1|refseq:NP_001317183.1|refseq:NP_001317185.1 go:"GO:0005634"(nucleus) - - figure legend:ST2 F2A|comment:proteins identified only in our induced samples in three MudPIT analyses with the more stringent BY-adjusted significance p<0.05|dataset:Brain Disease - Neurological Diseases & Disorders|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-daoy)|taxid:9606(Homo sapiens DAOY cerebellar medulloblastoma cell line) - 2020/12/29 2020/12/29 rogid:cn8gYfKDpQc8J2ygnqny32sIyyU9606 rogid:gYSfjHA8PY8nvLrWxnm2RxpNdnY9606 rigid:6EMs5+B89Q89RCR/2S2BG6PhH9E false tandem tag:n-n - - - psi-mi:"MI:0658"(multidimensional protein identification technology) psi-mi:"MI:0658"(multidimensional protein identification technology) uniprotkb:P48431 uniprotkb:Q9UBW7 intact:EBI-6124081|uniprotkb:Q14537|ensembl:ENSP00000323588 intact:EBI-2797576|uniprotkb:Q5W0T3|uniprotkb:O43434|uniprotkb:O43212|uniprotkb:Q5W0Q4|uniprotkb:Q9UEU2|uniprotkb:Q9H538|uniprotkb:Q9H0V5|uniprotkb:Q8NE39|uniprotkb:Q63HP0|uniprotkb:A6NI02|uniprotkb:A6NDG0|uniprotkb:O60898|ensembl:ENSP00000372324|ensembl:ENSP00000372327|ensembl:ENSP00000479904 psi-mi:sox2_human(display_long)|uniprotkb:SOX2(gene name)|psi-mi:SOX2(display_short) psi-mi:zmym2_human(display_long)|uniprotkb:FIM(gene name synonym)|uniprotkb:RAMP(gene name synonym)|uniprotkb:ZNF198(gene name synonym)|uniprotkb:Fused in myeloproliferative disorders protein(gene name synonym)|uniprotkb:Rearranged in atypical myeloproliferative disorder protein(gene name synonym)|uniprotkb:Zinc finger protein 198(gene name synonym)|uniprotkb:ZMYM2(gene name)|psi-mi:ZMYM2(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Cox et al. (2012) pubmed:23667531|imex:IM-28599 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-26574619|imex:IM-28599-5 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_003097.1|dip:DIP-59913N|ensembl:ENSG00000181449(gene)|ensembl:ENST00000325404(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001649"(osteoblast differentiation)|go:"GO:0001654"(eye development)|go:"GO:0001714"(endodermal cell fate specification)|go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006325"(chromatin organization)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0009611"(response to wounding)|go:"GO:0009653"(anatomical structure morphogenesis)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0021781"(glial cell fate commitment)|go:"GO:0021983"(pituitary gland development)|go:"GO:0021984"(adenohypophysis development)|go:"GO:0022409"(positive regulation of cell-cell adhesion)|go:"GO:0030154"(cell differentiation)|go:"GO:0030900"(forebrain development)|go:"GO:0035019"(somatic stem cell population maintenance)|go:"GO:0035198"(miRNA binding)|go:"GO:0042246"(tissue regeneration)|go:"GO:0043281"(regulation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0043410"(positive regulation of MAPK cascade)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045165"(cell fate commitment)|go:"GO:0045597"(positive regulation of cell differentiation)|go:"GO:0045665"(negative regulation of neuron differentiation)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048839"(inner ear development)|go:"GO:0050680"(negative regulation of epithelial cell proliferation)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0070848"(response to growth factor)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:0097150"(neuronal stem cell population maintenance)|interpro:IPR009071(High mobility group box, HMG)|interpro:IPR022097|interpro:IPR032643|interpro:IPR036910|mint:P48431|rcsb pdb:1O4X|rcsb pdb:2LE4|rcsb pdb:6T7B|rcsb pdb:6T90|rcsb pdb:6WX7|rcsb pdb:6WX8|rcsb pdb:6WX9|rcsb pdb:6YOV|reactome:R-HSA-2892245|reactome:R-HSA-2892247|reactome:R-HSA-3769402|reactome:R-HSA-452723|reactome:R-HSA-6785807|reactome:R-HSA-8986944 refseq:NP_001177893.1|refseq:NP_001177894.1|refseq:NP_003444.1|refseq:NP_932072.1|ensembl:ENSP00000372324|ensembl:ENSP00000372327|ensembl:ENSP00000479904|refseq:XP_005266577.1|ensembl:ENSG00000121741(gene)|ensembl:ENST00000382871(transcript)|ensembl:ENST00000382874(transcript)|ensembl:ENST00000610343(transcript)|go:"GO:0005829"(cytosol)|go:"GO:0008270"(zinc ion binding)|go:"GO:0016605"(PML body)|go:"GO:0031624"(ubiquitin conjugating enzyme binding)|interpro:IPR010507(Zinc finger, MYM-type)|interpro:IPR011017(TRASH)|interpro:IPR021893|mint:Q9UBW7|reactome:R-HSA-1839117|reactome:R-HSA-5655302|reactome:R-HSA-9703465|refseq:XP_016876218.1|refseq:XP_011533526.1 go:"GO:0005634"(nucleus) - - figure legend:ST2 F2A|comment:proteins identified only in our induced samples in three MudPIT analyses with the more stringent BY-adjusted significance p<0.05|dataset:Brain Disease - Neurological Diseases & Disorders|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-daoy)|taxid:9606(Homo sapiens DAOY cerebellar medulloblastoma cell line) - 2020/12/29 2020/12/29 rogid:cn8gYfKDpQc8J2ygnqny32sIyyU9606 rogid:rsxYDcDeR5x2Lt3phHNYpCjf9KA9606 rigid:6EMs5+B89Q89RCR/2S2BG6PhH9E false tandem tag:n-n - - - psi-mi:"MI:0658"(multidimensional protein identification technology) psi-mi:"MI:0658"(multidimensional protein identification technology) uniprotkb:P48431 uniprotkb:Q14999 intact:EBI-6124081|uniprotkb:Q14537|ensembl:ENSP00000323588 intact:EBI-308606|uniprotkb:Q5T654|ensembl:ENSP00000265348|uniprotkb:B4DYZ0|uniprotkb:F5H0L1 psi-mi:sox2_human(display_long)|uniprotkb:SOX2(gene name)|psi-mi:SOX2(display_short) psi-mi:cul7_human(display_long)|uniprotkb:CUL7(gene name)|psi-mi:CUL7(display_short)|uniprotkb:KIAA0076(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Cox et al. (2012) pubmed:23667531|imex:IM-28599 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-26574619|imex:IM-28599-5 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_003097.1|dip:DIP-59913N|ensembl:ENSG00000181449(gene)|ensembl:ENST00000325404(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001649"(osteoblast differentiation)|go:"GO:0001654"(eye development)|go:"GO:0001714"(endodermal cell fate specification)|go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006325"(chromatin organization)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0009611"(response to wounding)|go:"GO:0009653"(anatomical structure morphogenesis)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0021781"(glial cell fate commitment)|go:"GO:0021983"(pituitary gland development)|go:"GO:0021984"(adenohypophysis development)|go:"GO:0022409"(positive regulation of cell-cell adhesion)|go:"GO:0030154"(cell differentiation)|go:"GO:0030900"(forebrain development)|go:"GO:0035019"(somatic stem cell population maintenance)|go:"GO:0035198"(miRNA binding)|go:"GO:0042246"(tissue regeneration)|go:"GO:0043281"(regulation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0043410"(positive regulation of MAPK cascade)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045165"(cell fate commitment)|go:"GO:0045597"(positive regulation of cell differentiation)|go:"GO:0045665"(negative regulation of neuron differentiation)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048839"(inner ear development)|go:"GO:0050680"(negative regulation of epithelial cell proliferation)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0070848"(response to growth factor)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:0097150"(neuronal stem cell population maintenance)|interpro:IPR009071(High mobility group box, HMG)|interpro:IPR022097|interpro:IPR032643|interpro:IPR036910|mint:P48431|rcsb pdb:1O4X|rcsb pdb:2LE4|rcsb pdb:6T7B|rcsb pdb:6T90|rcsb pdb:6WX7|rcsb pdb:6WX8|rcsb pdb:6WX9|rcsb pdb:6YOV|reactome:R-HSA-2892245|reactome:R-HSA-2892247|reactome:R-HSA-3769402|reactome:R-HSA-452723|reactome:R-HSA-6785807|reactome:R-HSA-8986944 ensembl:ENSG00000044090(gene)|ensembl:ENST00000265348(transcript)|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0000281"(mitotic cytokinesis)|go:"GO:0001570"(vasculogenesis)|go:"GO:0001837"(epithelial to mesenchymal transition)|go:"GO:0001890"(placenta development)|go:"GO:0005680"(anaphase-promoting complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0006508"(proteolysis)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0007030"(Golgi organization)|go:"GO:0007088"(regulation of mitotic nuclear division)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0031461"(cullin-RING ubiquitin ligase complex)|go:"GO:0031467"(Cul7-RING ubiquitin ligase complex)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0050775"(positive regulation of dendrite morphogenesis)|go:"GO:1990393"(3M complex)|interpro:IPR001373(Cullin, N-terminal region)|interpro:IPR004939(Anaphase-promoting complex, subunit 10)|interpro:IPR008979(Galactose-binding like)|interpro:IPR014722(Translation protein SH3-like, subgroup)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR016158(Cullin homology)|interpro:IPR019559|interpro:IPR021097|interpro:IPR031223|interpro:IPR036317|interpro:IPR036388|mint:Q14999|rcsb pdb:2JNG|reactome:R-HSA-381038|reactome:R-HSA-8951664|reactome:R-HSA-983168|refseq:NP_001161842.1|refseq:NP_055595.2|dip:DIP-31618N|dip:DIP-60187N go:"GO:0005634"(nucleus) - - figure legend:ST2 F2A|comment:proteins identified only in our induced samples in three MudPIT analyses with the more stringent BY-adjusted significance p<0.05|dataset:Brain Disease - Neurological Diseases & Disorders|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-daoy)|taxid:9606(Homo sapiens DAOY cerebellar medulloblastoma cell line) - 2020/12/29 2020/12/29 rogid:cn8gYfKDpQc8J2ygnqny32sIyyU9606 rogid:8sODZSppCsuEgRmhSHp3UjwOf2M9606 rigid:6EMs5+B89Q89RCR/2S2BG6PhH9E false tandem tag:n-n - - - psi-mi:"MI:0658"(multidimensional protein identification technology) psi-mi:"MI:0658"(multidimensional protein identification technology) uniprotkb:P48431 uniprotkb:Q96JM2 intact:EBI-6124081|uniprotkb:Q14537|ensembl:ENSP00000323588 intact:EBI-1210359|uniprotkb:Q8N408|uniprotkb:Q5T0T4|intact:EBI-28975500|ensembl:ENSP00000277225 psi-mi:sox2_human(display_long)|uniprotkb:SOX2(gene name)|psi-mi:SOX2(display_short) psi-mi:zn462_human(display_long)|uniprotkb:ZNF462(gene name)|psi-mi:ZNF462(display_short)|uniprotkb:KIAA1803(gene name synonym)|uniprotkb:Zinc finger PBX1-interacting protein(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Cox et al. (2012) pubmed:23667531|imex:IM-28599 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-26574619|imex:IM-28599-5 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_003097.1|dip:DIP-59913N|ensembl:ENSG00000181449(gene)|ensembl:ENST00000325404(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001649"(osteoblast differentiation)|go:"GO:0001654"(eye development)|go:"GO:0001714"(endodermal cell fate specification)|go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006325"(chromatin organization)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0009611"(response to wounding)|go:"GO:0009653"(anatomical structure morphogenesis)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0021781"(glial cell fate commitment)|go:"GO:0021983"(pituitary gland development)|go:"GO:0021984"(adenohypophysis development)|go:"GO:0022409"(positive regulation of cell-cell adhesion)|go:"GO:0030154"(cell differentiation)|go:"GO:0030900"(forebrain development)|go:"GO:0035019"(somatic stem cell population maintenance)|go:"GO:0035198"(miRNA binding)|go:"GO:0042246"(tissue regeneration)|go:"GO:0043281"(regulation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0043410"(positive regulation of MAPK cascade)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045165"(cell fate commitment)|go:"GO:0045597"(positive regulation of cell differentiation)|go:"GO:0045665"(negative regulation of neuron differentiation)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048839"(inner ear development)|go:"GO:0050680"(negative regulation of epithelial cell proliferation)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0070848"(response to growth factor)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:0097150"(neuronal stem cell population maintenance)|interpro:IPR009071(High mobility group box, HMG)|interpro:IPR022097|interpro:IPR032643|interpro:IPR036910|mint:P48431|rcsb pdb:1O4X|rcsb pdb:2LE4|rcsb pdb:6T7B|rcsb pdb:6T90|rcsb pdb:6WX7|rcsb pdb:6WX8|rcsb pdb:6WX9|rcsb pdb:6YOV|reactome:R-HSA-2892245|reactome:R-HSA-2892247|reactome:R-HSA-3769402|reactome:R-HSA-452723|reactome:R-HSA-6785807|reactome:R-HSA-8986944 refseq:NP_067047.4|ensembl:ENSP00000277225|ensembl:ENST00000441147|ensembl:ENSP00000397306|refseq:XP_006717278.1|refseq:XP_006717279.1|dip:DIP-39340N|ensembl:ENSG00000148143(gene)|ensembl:ENST00000277225(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0006325"(chromatin organization)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0043392"(negative regulation of DNA binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR036236|mint:Q96JM2|rcsb pdb:1X6F go:"GO:0005634"(nucleus) - - figure legend:ST2 F2A|comment:proteins identified only in our induced samples in three MudPIT analyses with the more stringent BY-adjusted significance p<0.05|dataset:Brain Disease - Neurological Diseases & Disorders|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-daoy)|taxid:9606(Homo sapiens DAOY cerebellar medulloblastoma cell line) - 2020/12/29 2020/12/29 rogid:cn8gYfKDpQc8J2ygnqny32sIyyU9606 rogid:ftIOu4wVkBWJw+4aHw+R+nN44Vc9606 rigid:6EMs5+B89Q89RCR/2S2BG6PhH9E false tandem tag:n-n - - - psi-mi:"MI:0658"(multidimensional protein identification technology) psi-mi:"MI:0658"(multidimensional protein identification technology) uniprotkb:P48431 uniprotkb:Q01167 intact:EBI-6124081|uniprotkb:Q14537|ensembl:ENSP00000323588 intact:EBI-2509991|intact:EBI-28976610|ensembl:ENSP00000335677|uniprotkb:Q13624|uniprotkb:Q13623|uniprotkb:A6NEP5|uniprotkb:Q13622 psi-mi:sox2_human(display_long)|uniprotkb:SOX2(gene name)|psi-mi:SOX2(display_short) psi-mi:foxk2_human(display_long)|uniprotkb:G/T-mismatch specific binding protein(gene name synonym)|uniprotkb:FOXK2(gene name)|psi-mi:FOXK2(display_short)|uniprotkb:ILF(gene name synonym)|uniprotkb:ILF1(gene name synonym)|uniprotkb:Interleukin enhancer-binding factor 1(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Cox et al. (2012) pubmed:23667531|imex:IM-28599 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-26574619|imex:IM-28599-5 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_003097.1|dip:DIP-59913N|ensembl:ENSG00000181449(gene)|ensembl:ENST00000325404(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001649"(osteoblast differentiation)|go:"GO:0001654"(eye development)|go:"GO:0001714"(endodermal cell fate specification)|go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006325"(chromatin organization)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0009611"(response to wounding)|go:"GO:0009653"(anatomical structure morphogenesis)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0021781"(glial cell fate commitment)|go:"GO:0021983"(pituitary gland development)|go:"GO:0021984"(adenohypophysis development)|go:"GO:0022409"(positive regulation of cell-cell adhesion)|go:"GO:0030154"(cell differentiation)|go:"GO:0030900"(forebrain development)|go:"GO:0035019"(somatic stem cell population maintenance)|go:"GO:0035198"(miRNA binding)|go:"GO:0042246"(tissue regeneration)|go:"GO:0043281"(regulation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0043410"(positive regulation of MAPK cascade)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045165"(cell fate commitment)|go:"GO:0045597"(positive regulation of cell differentiation)|go:"GO:0045665"(negative regulation of neuron differentiation)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048839"(inner ear development)|go:"GO:0050680"(negative regulation of epithelial cell proliferation)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0070848"(response to growth factor)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:0097150"(neuronal stem cell population maintenance)|interpro:IPR009071(High mobility group box, HMG)|interpro:IPR022097|interpro:IPR032643|interpro:IPR036910|mint:P48431|rcsb pdb:1O4X|rcsb pdb:2LE4|rcsb pdb:6T7B|rcsb pdb:6T90|rcsb pdb:6WX7|rcsb pdb:6WX8|rcsb pdb:6WX9|rcsb pdb:6YOV|reactome:R-HSA-2892245|reactome:R-HSA-2892247|reactome:R-HSA-3769402|reactome:R-HSA-452723|reactome:R-HSA-6785807|reactome:R-HSA-8986944 ensembl:ENSG00000141568(gene)|ensembl:ENST00000335255(transcript)|go:"GO:0000287"(magnesium ion binding)|go:"GO:0000785"(chromatin)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001678"(cellular glucose homeostasis)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0010507"(negative regulation of autophagy)|go:"GO:0010906"(regulation of glucose metabolic process)|go:"GO:0042594"(response to starvation)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|interpro:IPR000253(Forkhead-associated)|interpro:IPR001766(Fork head transcription factor)|interpro:IPR008984(SMAD/FHA domain)|interpro:IPR018122|go:"GO:0061621"(canonical glycolysis)|interpro:IPR030456|interpro:IPR036388|interpro:IPR036390|mint:Q01167|rcsb pdb:1JXS|rcsb pdb:2C6Y|reactome:R-HSA-5689603|ensembl:ENSP00000335677|ensembl:ENST00000473637|ensembl:ENSP00000436108|refseq:NP_004505.2 go:"GO:0005634"(nucleus) - - figure legend:ST2 F2A|comment:proteins identified only in our induced samples in three MudPIT analyses with the more stringent BY-adjusted significance p<0.05|dataset:Brain Disease - Neurological Diseases & Disorders|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-daoy)|taxid:9606(Homo sapiens DAOY cerebellar medulloblastoma cell line) - 2020/12/29 2020/12/29 rogid:cn8gYfKDpQc8J2ygnqny32sIyyU9606 rogid:mGYtlnM3enVAuU82j5hQ0sui3F49606 rigid:6EMs5+B89Q89RCR/2S2BG6PhH9E false tandem tag:n-n - - - psi-mi:"MI:0658"(multidimensional protein identification technology) psi-mi:"MI:0658"(multidimensional protein identification technology) uniprotkb:P48431 uniprotkb:Q9Y2J4 intact:EBI-6124081|uniprotkb:Q14537|ensembl:ENSP00000323588 intact:EBI-746752|intact:EBI-28986657|ensembl:ENSP00000409999|uniprotkb:Q53EP1|uniprotkb:Q96F99|uniprotkb:Q9UKB4|uniprotkb:A8K6F1|uniprotkb:B7Z5Q1|uniprotkb:E9PHW3 psi-mi:sox2_human(display_long)|uniprotkb:SOX2(gene name)|psi-mi:SOX2(display_short) psi-mi:amol2_human(display_long)|uniprotkb:Leman coiled-coil protein(gene name synonym)|uniprotkb:AMOTL2(gene name)|psi-mi:AMOTL2(display_short)|uniprotkb:KIAA0989(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Cox et al. (2012) pubmed:23667531|imex:IM-28599 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-26574619|imex:IM-28599-5 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_003097.1|dip:DIP-59913N|ensembl:ENSG00000181449(gene)|ensembl:ENST00000325404(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001649"(osteoblast differentiation)|go:"GO:0001654"(eye development)|go:"GO:0001714"(endodermal cell fate specification)|go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006325"(chromatin organization)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0009611"(response to wounding)|go:"GO:0009653"(anatomical structure morphogenesis)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0021781"(glial cell fate commitment)|go:"GO:0021983"(pituitary gland development)|go:"GO:0021984"(adenohypophysis development)|go:"GO:0022409"(positive regulation of cell-cell adhesion)|go:"GO:0030154"(cell differentiation)|go:"GO:0030900"(forebrain development)|go:"GO:0035019"(somatic stem cell population maintenance)|go:"GO:0035198"(miRNA binding)|go:"GO:0042246"(tissue regeneration)|go:"GO:0043281"(regulation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0043410"(positive regulation of MAPK cascade)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045165"(cell fate commitment)|go:"GO:0045597"(positive regulation of cell differentiation)|go:"GO:0045665"(negative regulation of neuron differentiation)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048839"(inner ear development)|go:"GO:0050680"(negative regulation of epithelial cell proliferation)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0070848"(response to growth factor)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:0097150"(neuronal stem cell population maintenance)|interpro:IPR009071(High mobility group box, HMG)|interpro:IPR022097|interpro:IPR032643|interpro:IPR036910|mint:P48431|rcsb pdb:1O4X|rcsb pdb:2LE4|rcsb pdb:6T7B|rcsb pdb:6T90|rcsb pdb:6WX7|rcsb pdb:6WX8|rcsb pdb:6WX9|rcsb pdb:6YOV|reactome:R-HSA-2892245|reactome:R-HSA-2892247|reactome:R-HSA-3769402|reactome:R-HSA-452723|reactome:R-HSA-6785807|reactome:R-HSA-8986944 refseq:NP_001265612.1|refseq:NP_001265614.1|ensembl:ENSG00000114019(gene)|refseq:XP_006713717.1|refseq:NP_057285.3|refseq:XP_011511183.1|ensembl:ENST00000422605(transcript)|go:"GO:0001525"(angiogenesis)|go:"GO:0003365"(establishment of cell polarity involved in ameboidal cell migration)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005923"(bicellular tight junction)|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0030036"(actin cytoskeleton organization)|go:"GO:0030334"(regulation of cell migration)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0035329"(hippo signaling)|go:"GO:0055037"(recycling endosome)|interpro:IPR009114(Angiomotin)|interpro:IPR024646|mint:Q9Y2J4|reactome:R-HSA-2028269|refseq:XP_016862069.1|refseq:XP_016862070.1|refseq:XP_016862071.1|ensembl:ENST00000249883|ensembl:ENSP00000249883|ensembl:ENSP00000409999|ensembl:ENST00000513145|ensembl:ENSP00000425475|ensembl:ENST00000514516|ensembl:ENSP00000424765|dip:DIP-57510N go:"GO:0005634"(nucleus) - - figure legend:ST2 F2A|comment:proteins identified only in our induced samples in three MudPIT analyses with the more stringent BY-adjusted significance p<0.05|dataset:Brain Disease - Neurological Diseases & Disorders|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-daoy)|taxid:9606(Homo sapiens DAOY cerebellar medulloblastoma cell line) - 2020/12/29 2020/12/29 rogid:cn8gYfKDpQc8J2ygnqny32sIyyU9606 rogid:SHtKAcLLnTpSSLwVE7yQ1WECoZk9606 rigid:6EMs5+B89Q89RCR/2S2BG6PhH9E false tandem tag:n-n - - - psi-mi:"MI:0658"(multidimensional protein identification technology) psi-mi:"MI:0658"(multidimensional protein identification technology) uniprotkb:P48431 uniprotkb:Q9UPN7 intact:EBI-6124081|uniprotkb:Q14537|ensembl:ENSP00000323588 intact:EBI-359745|uniprotkb:Q2M2H3|uniprotkb:Q504V2|uniprotkb:Q6NVJ6|uniprotkb:Q9BU97|intact:EBI-28973105|ensembl:ENSP00000414202|ensembl:ENSP00000467521 psi-mi:sox2_human(display_long)|uniprotkb:SOX2(gene name)|psi-mi:SOX2(display_short) psi-mi:pp6r1_human(display_long)|uniprotkb:PPP6R1(gene name)|psi-mi:PPP6R1(display_short)|uniprotkb:KIAA1115(gene name synonym)|uniprotkb:PP6R1(gene name synonym)|uniprotkb:SAPS domain family member 1(gene name synonym)|uniprotkb:SAPS1(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Cox et al. (2012) pubmed:23667531|imex:IM-28599 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-26574619|imex:IM-28599-5 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_003097.1|dip:DIP-59913N|ensembl:ENSG00000181449(gene)|ensembl:ENST00000325404(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001649"(osteoblast differentiation)|go:"GO:0001654"(eye development)|go:"GO:0001714"(endodermal cell fate specification)|go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006325"(chromatin organization)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0009611"(response to wounding)|go:"GO:0009653"(anatomical structure morphogenesis)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0021781"(glial cell fate commitment)|go:"GO:0021983"(pituitary gland development)|go:"GO:0021984"(adenohypophysis development)|go:"GO:0022409"(positive regulation of cell-cell adhesion)|go:"GO:0030154"(cell differentiation)|go:"GO:0030900"(forebrain development)|go:"GO:0035019"(somatic stem cell population maintenance)|go:"GO:0035198"(miRNA binding)|go:"GO:0042246"(tissue regeneration)|go:"GO:0043281"(regulation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0043410"(positive regulation of MAPK cascade)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045165"(cell fate commitment)|go:"GO:0045597"(positive regulation of cell differentiation)|go:"GO:0045665"(negative regulation of neuron differentiation)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048839"(inner ear development)|go:"GO:0050680"(negative regulation of epithelial cell proliferation)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0070848"(response to growth factor)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:0097150"(neuronal stem cell population maintenance)|interpro:IPR009071(High mobility group box, HMG)|interpro:IPR022097|interpro:IPR032643|interpro:IPR036910|mint:P48431|rcsb pdb:1O4X|rcsb pdb:2LE4|rcsb pdb:6T7B|rcsb pdb:6T90|rcsb pdb:6WX7|rcsb pdb:6WX8|rcsb pdb:6WX9|rcsb pdb:6YOV|reactome:R-HSA-2892245|reactome:R-HSA-2892247|reactome:R-HSA-3769402|reactome:R-HSA-452723|reactome:R-HSA-6785807|reactome:R-HSA-8986944 refseq:NP_055746.3|ensembl:ENSP00000414202|ensembl:ENSP00000467521|ensembl:ENSG00000105063(gene)|ensembl:ENST00000412770(transcript)|ensembl:ENST00000587283(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0019888"(protein phosphatase regulator activity)|go:"GO:0019903"(protein phosphatase binding)|go:"GO:0031267"(small GTPase binding)|go:"GO:0043666"(regulation of phosphoprotein phosphatase activity)|interpro:IPR007587(SIT4 phosphatase-associated protein)|interpro:IPR016024(Armadillo-type fold)|mint:Q9UPN7|reactome:R-HSA-204005|dip:DIP-27589N go:"GO:0005634"(nucleus) - - figure legend:ST2 F2A|comment:proteins identified only in our induced samples in three MudPIT analyses with the more stringent BY-adjusted significance p<0.05|dataset:Brain Disease - Neurological Diseases & Disorders|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-daoy)|taxid:9606(Homo sapiens DAOY cerebellar medulloblastoma cell line) - 2020/12/29 2020/12/29 rogid:cn8gYfKDpQc8J2ygnqny32sIyyU9606 rogid:Nab2lMgz1rQizyvjdbMrJUMNB+I9606 rigid:6EMs5+B89Q89RCR/2S2BG6PhH9E false tandem tag:n-n - - - psi-mi:"MI:0658"(multidimensional protein identification technology) psi-mi:"MI:0658"(multidimensional protein identification technology) uniprotkb:P48431 uniprotkb:P35222 intact:EBI-6124081|uniprotkb:Q14537|ensembl:ENSP00000323588 intact:EBI-491549|uniprotkb:Q8NEW9|uniprotkb:Q8NI94|uniprotkb:Q9H391|ensembl:ENSP00000344456|ensembl:ENSP00000379486|ensembl:ENSP00000379488|ensembl:ENSP00000385604|ensembl:ENSP00000387455|ensembl:ENSP00000401599|ensembl:ENSP00000409302|ensembl:ENSP00000412219|ensembl:ENSP00000493533|ensembl:ENSP00000493610|ensembl:ENSP00000494053|ensembl:ENSP00000494411|ensembl:ENSP00000494677|ensembl:ENSP00000494845|ensembl:ENSP00000494914|ensembl:ENSP00000495076|ensembl:ENSP00000495244|ensembl:ENSP00000495360|ensembl:ENSP00000495450|ensembl:ENSP00000495719|ensembl:ENSP00000495992|ensembl:ENSP00000496021|ensembl:ENSP00000496180|ensembl:ENSP00000496385|uniprotkb:A8K1L7|intact:EBI-491563 psi-mi:sox2_human(display_long)|uniprotkb:SOX2(gene name)|psi-mi:SOX2(display_short) psi-mi:ctnb1_human(display_long)|uniprotkb:Beta-catenin(gene name synonym)|uniprotkb:OK/SW-cl.35(orf name)|uniprotkb:PRO2286(orf name)|uniprotkb:CTNNB1(gene name)|psi-mi:CTNNB1(display_short)|uniprotkb:CTNNB(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Cox et al. (2012) pubmed:23667531|imex:IM-28599 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-26574619|imex:IM-28599-5 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_003097.1|dip:DIP-59913N|ensembl:ENSG00000181449(gene)|ensembl:ENST00000325404(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001649"(osteoblast differentiation)|go:"GO:0001654"(eye development)|go:"GO:0001714"(endodermal cell fate specification)|go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006325"(chromatin organization)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0009611"(response to wounding)|go:"GO:0009653"(anatomical structure morphogenesis)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0021781"(glial cell fate commitment)|go:"GO:0021983"(pituitary gland development)|go:"GO:0021984"(adenohypophysis development)|go:"GO:0022409"(positive regulation of cell-cell adhesion)|go:"GO:0030154"(cell differentiation)|go:"GO:0030900"(forebrain development)|go:"GO:0035019"(somatic stem cell population maintenance)|go:"GO:0035198"(miRNA binding)|go:"GO:0042246"(tissue regeneration)|go:"GO:0043281"(regulation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0043410"(positive regulation of MAPK cascade)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045165"(cell fate commitment)|go:"GO:0045597"(positive regulation of cell differentiation)|go:"GO:0045665"(negative regulation of neuron differentiation)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048839"(inner ear development)|go:"GO:0050680"(negative regulation of epithelial cell proliferation)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0070848"(response to growth factor)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:0097150"(neuronal stem cell population maintenance)|interpro:IPR009071(High mobility group box, HMG)|interpro:IPR022097|interpro:IPR032643|interpro:IPR036910|mint:P48431|rcsb pdb:1O4X|rcsb pdb:2LE4|rcsb pdb:6T7B|rcsb pdb:6T90|rcsb pdb:6WX7|rcsb pdb:6WX8|rcsb pdb:6WX9|rcsb pdb:6YOV|reactome:R-HSA-2892245|reactome:R-HSA-2892247|reactome:R-HSA-3769402|reactome:R-HSA-452723|reactome:R-HSA-6785807|reactome:R-HSA-8986944 ensembl:ENSG00000168036(gene)|ensembl:ENST00000349496(transcript)|ensembl:ENST00000396183(transcript)|ensembl:ENST00000396185(transcript)|ensembl:ENST00000405570(transcript)|ensembl:ENST00000431914(transcript)|ensembl:ENST00000441708(transcript)|ensembl:ENST00000450969(transcript)|ensembl:ENST00000642248(transcript)|ensembl:ENST00000642315(transcript)|ensembl:ENST00000642426(transcript)|ensembl:ENST00000642992(transcript)|ensembl:ENST00000643031(transcript)|ensembl:ENST00000643297(transcript)|ensembl:ENST00000643541(transcript)|ensembl:ENST00000643977(transcript)|ensembl:ENST00000643992(transcript)|ensembl:ENST00000644867(transcript)|ensembl:ENST00000645210(transcript)|ensembl:ENST00000645320(transcript)|ensembl:ENST00000645982(transcript)|ensembl:ENST00000433400(transcript)|ensembl:ENST00000646369(transcript)|ensembl:ENST00000647390(transcript)|ensembl:ENST00000646725(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0000578"(embryonic axis specification)|reactome:R-HSA-351906|reactome:R-HSA-3769402|reactome:R-HSA-3134973|reactome:R-HSA-381771|reactome:R-HSA-4086398|reactome:R-HSA-418990|reactome:R-HSA-4411364|reactome:R-HSA-4641262|reactome:R-HSA-5218920|reactome:R-HSA-525793|reactome:R-HSA-5339716|reactome:R-HSA-5358747|reactome:R-HSA-5358749|reactome:R-HSA-5358751|reactome:R-HSA-5358752|reactome:R-HSA-5626467|reactome:R-HSA-8853884|reactome:R-HSA-8876493|reactome:R-HSA-8951430|go:"GO:0045765"(regulation of angiogenesis)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0045976"(negative regulation of mitotic cell cycle, embryonic)|go:"GO:0046332"(SMAD binding)|go:"GO:0048145"(regulation of fibroblast proliferation)|go:"GO:0048469"(cell maturation)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0048489"(synaptic vesicle transport)|go:"GO:0048538"(thymus development)|go:"GO:0048599"(oocyte development)|go:"GO:0048617"(embryonic foregut morphogenesis)|go:"GO:0048643"(positive regulation of skeletal muscle tissue development)|go:"GO:0048660"(regulation of smooth muscle cell proliferation)|go:"GO:0045743"(positive regulation of fibroblast growth factor receptor signaling pathway)|go:"GO:0048715"(negative regulation of oligodendrocyte differentiation)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0010718"(positive regulation of epithelial to mesenchymal transition)|go:"GO:0010909"(positive regulation of heparan sulfate proteoglycan biosynthetic process)|go:"GO:0016020"(membrane)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016327"(apicolateral plasma membrane)|go:"GO:0016328"(lateral plasma membrane)|go:"GO:0016342"(catenin complex)|go:"GO:0016525"(negative regulation of angiogenesis)|go:"GO:0016600"(flotillin complex)|go:"GO:0016922"(nuclear receptor binding)|go:"GO:0019827"(stem cell population maintenance)|go:"GO:0019899"(enzyme binding)|go:"GO:0019900"(kinase binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0019903"(protein phosphatase binding)|go:"GO:0021819"(layer formation in cerebral cortex)|go:"GO:0022009"(central nervous system vasculogenesis)|go:"GO:0030018"(Z disc)|go:"GO:0030027"(lamellipodium)|go:"GO:0030054"(cell junction)|go:"GO:0030316"(osteoclast differentiation)|go:"GO:0030331"(estrogen receptor binding)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0030539"(male genitalia development)|go:"GO:0030877"(beta-catenin destruction complex)|go:"GO:0030902"(hindbrain development)|go:"GO:0030997"(regulation of centriole-centriole cohesion)|go:"GO:0031016"(pancreas development)|go:"GO:0031069"(hair follicle morphogenesis)|go:"GO:0031528"(microvillus membrane)|go:"GO:0031641"(regulation of myelination)|go:"GO:0032212"(positive regulation of telomere maintenance via telomerase)|go:"GO:0032331"(negative regulation of chondrocyte differentiation)|go:"GO:0032355"(response to estradiol)|go:"GO:0032968"(positive regulation of transcription elongation from RNA polymerase II promoter)|go:"GO:0032991"(protein-containing complex)|go:"GO:0032993"(protein-DNA complex)|go:"GO:0033077"(T cell differentiation in thymus)|go:"GO:0033234"(negative regulation of protein sumoylation)|go:"GO:0034333"(adherens junction assembly)|go:"GO:0034394"(protein localization to cell surface)|go:"GO:0034750"(Scrib-APC-beta-catenin complex)|go:"GO:0035050"(embryonic heart tube development)|go:"GO:0035112"(genitalia morphogenesis)|go:"GO:0035115"(embryonic forelimb morphogenesis)|go:"GO:0035116"(embryonic hindlimb morphogenesis)|go:"GO:0035315"(hair cell differentiation)|go:"GO:0035995"(detection of muscle stretch)|go:"GO:0036023"(embryonic skeletal limb joint morphogenesis)|go:"GO:0036520"(astrocyte-dopaminergic neuron signaling)|go:"GO:0042129"(regulation of T cell proliferation)|go:"GO:0042475"(odontogenesis of dentin-containing tooth)|go:"GO:0042493"|go:"GO:0042733"(embryonic digit morphogenesis)|go:"GO:0042734"(presynaptic membrane)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0043410"(positive regulation of MAPK cascade)|go:"GO:0043525"(positive regulation of neuron apoptotic process)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0044334"(canonical Wnt signaling pathway involved in positive regulation of epithelial to mesenchymal transition)|go:"GO:0044336"(canonical Wnt signaling pathway involved in negative regulation of apoptotic process)|go:"GO:0044338"(canonical Wnt signaling pathway involved in mesenchymal stem cell differentiation)|go:"GO:0045177"(apical part of cell)|go:"GO:0045202"(synapse)|go:"GO:0045211"(postsynaptic membrane)|go:"GO:0045294"(alpha-catenin binding)|go:"GO:0045296"(cadherin binding)|go:"GO:0045453"(bone resorption)|go:"GO:0045603"(positive regulation of endothelial cell differentiation)|go:"GO:0045669"(positive regulation of osteoblast differentiation)|go:"GO:0045671"(negative regulation of osteoclast differentiation)|go:"GO:0060441"(epithelial tube branching involved in lung morphogenesis)|go:"GO:0060479"(lung cell differentiation)|go:"GO:0060484"(lung-associated mesenchyme development)|go:"GO:0060492"(lung induction)|go:"GO:0050767"(regulation of neurogenesis)|go:"GO:0050808"(synapse organization)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0060742"(epithelial cell differentiation involved in prostate gland development)|go:"GO:0060769"(positive regulation of epithelial cell proliferation involved in prostate gland development)|go:"GO:0051145"(smooth muscle cell differentiation)|go:"GO:0051571"(positive regulation of histone H3-K4 methylation)|go:"GO:0051884"(regulation of timing of anagen)|go:"GO:0051973"(positive regulation of telomerase activity)|go:"GO:0060789"(hair follicle placode formation)|go:"GO:0060916"(mesenchymal cell proliferation involved in lung development)|go:"GO:0061047"(positive regulation of branching involved in lung morphogenesis)|go:"GO:0061154"(endothelial tube morphogenesis)|go:"GO:0061198"(fungiform papilla formation)|go:"GO:0061324"(canonical Wnt signaling pathway involved in positive regulation of cardiac outflow tract cell proliferation)|go:"GO:0061549"(sympathetic ganglion development)|go:"GO:0061550"(cranial ganglion development)|go:"GO:0060066"(oviduct development)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070369"(beta-catenin-TCF7L2 complex)|go:"GO:0070411"(I-SMAD binding)|go:"GO:0070602"(regulation of centromeric sister chromatid cohesion)|go:"GO:0071363"(cellular response to growth factor stimulus)|go:"GO:0071681"(cellular response to indole-3-methanol)|go:"GO:0071944"(cell periphery)|go:"GO:0072033"(renal vesicle formation)|go:"GO:0060070"(canonical Wnt signaling pathway)|go:"GO:0060440"(trachea formation)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005912"(adherens junction)|go:"GO:0005923"(bicellular tight junction)|go:"GO:0005925"(focal adhesion)|go:"GO:0005938"(cell cortex)|go:"GO:0007155"(cell adhesion)|go:"GO:0007160"(cell-matrix adhesion)|go:"GO:0007268"(chemical synaptic transmission)|go:"GO:0007398"(ectoderm development)|go:"GO:0007403"(glial cell fate determination)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0005916"(fascia adherens)|go:"GO:0008134"(transcription factor binding)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0009948"(anterior/posterior axis specification)|go:"GO:0009950"(dorsal/ventral axis specification)|go:"GO:0009954"(proximal/distal pattern formation)|go:"GO:0072054"(renal outer medulla development)|go:"GO:0072079"(nephron tubule formation)|go:"GO:0072182"(regulation of nephron tubule epithelial cell differentiation)|go:"GO:0090279"(regulation of calcium ion import)|go:"GO:0097091"(synaptic vesicle clustering)|go:"GO:0097718"(disordered domain specific binding)|go:"GO:0098609"(cell-cell adhesion)|go:"GO:0098685"(Schaffer collateral - CA1 synapse)|go:"GO:0098831"(presynaptic active zone cytoplasmic component)|go:"GO:0099092"(postsynaptic density, intracellular component)|go:"GO:0140297"(DNA-binding transcription factor binding)|go:"GO:1903204"(negative regulation of oxidative stress-induced neuron death)|go:"GO:1904798"(positive regulation of core promoter binding)|go:"GO:1904888"(cranial skeletal system development)|go:"GO:1904948"(midbrain dopaminergic neuron differentiation)|go:"GO:1904954"(canonical Wnt signaling pathway involved in midbrain dopaminergic neuron differentiation)|go:"GO:1990138"(neuron projection extension)|go:"GO:1990226"(histone methyltransferase binding)|go:"GO:1990403"(embryonic brain development)|go:"GO:1990791"(dorsal root ganglion development)|go:"GO:1990907"(beta-catenin-TCF complex)|go:"GO:1990909"(Wnt signalosome)|go:"GO:2000008"(regulation of protein localization to cell surface)|go:"GO:2000017"(positive regulation of determination of dorsal identity)|go:"GO:2001234"(negative regulation of apoptotic signaling pathway)|interpro:IPR000225(Armadillo)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR013284(Beta-catenin)|interpro:IPR016024(Armadillo-type fold)|mint:P35222|rcsb pdb:1G3J|rcsb pdb:1JDH|rcsb pdb:1JPW|rcsb pdb:1LUJ|rcsb pdb:1P22|rcsb pdb:1QZ7|rcsb pdb:1T08|rcsb pdb:1TH1|rcsb pdb:2G57|rcsb pdb:2GL7|rcsb pdb:2Z6H|rcsb pdb:3DIW|rcsb pdb:3FQN|rcsb pdb:3FQR|rcsb pdb:3SL9|rcsb pdb:3SLA|rcsb pdb:3TX7|rcsb pdb:4DJS|rcsb pdb:6M90|rcsb pdb:6M91|rcsb pdb:6M92|rcsb pdb:6M93|rcsb pdb:6M94|rcsb pdb:6O9B|rcsb pdb:6O9C|rcsb pdb:6WLX|rcsb pdb:6WNX|rcsb pdb:7AFW|go:"GO:0072053"(renal inner medulla development)|rcsb pdb:7AR4|reactome:R-HSA-195253|reactome:R-HSA-196299|reactome:R-HSA-201681|reactome:R-HSA-201722|go:"GO:0000791"(euchromatin)|go:"GO:0000922"(spindle pole)|go:"GO:0001221"(transcription coregulator binding)|go:"GO:0001569"(branching involved in blood vessel morphogenesis)|go:"GO:0001658"(branching involved in ureteric bud morphogenesis)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0001702"(gastrulation with mouth forming second)|go:"GO:0001708"(cell fate specification)|go:"GO:0001711"(endodermal cell fate commitment)|go:"GO:0001764"(neuron migration)|go:"GO:0001837"(epithelial to mesenchymal transition)|go:"GO:0001840"(neural plate development)|go:"GO:0002052"(positive regulation of neuroblast proliferation)|go:"GO:0002053"(positive regulation of mesenchymal cell proliferation)|go:"GO:0002089"(lens morphogenesis in camera-type eye)|go:"GO:0003266"(regulation of secondary heart field cardioblast proliferation)|go:"GO:0003338"(metanephros morphogenesis)|go:"GO:0003340"(negative regulation of mesenchymal to epithelial transition involved in metanephros morphogenesis)|go:"GO:0003682"(chromatin binding)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0000904"(cell morphogenesis involved in differentiation)|dip:DIP-122N|refseq:NP_001091679.1|refseq:NP_001091680.1|refseq:NP_001895.1|refseq:XP_005264943.1|refseq:XP_016861227.1 go:"GO:0005634"(nucleus) - - figure legend:ST2 F2A|comment:proteins identified only in our induced samples in three MudPIT analyses with the more stringent BY-adjusted significance p<0.05|dataset:Brain Disease - Neurological Diseases & Disorders|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-daoy)|taxid:9606(Homo sapiens DAOY cerebellar medulloblastoma cell line) - 2020/12/29 2020/12/29 rogid:cn8gYfKDpQc8J2ygnqny32sIyyU9606 rogid:WLs7+T0WG4DiBStdS5+lR7i83dk9606 rigid:6EMs5+B89Q89RCR/2S2BG6PhH9E false tandem tag:n-n - - - psi-mi:"MI:0658"(multidimensional protein identification technology) psi-mi:"MI:0658"(multidimensional protein identification technology) uniprotkb:P48431 uniprotkb:P78406 intact:EBI-6124081|uniprotkb:Q14537|ensembl:ENSP00000323588 intact:EBI-724495|uniprotkb:O15306|uniprotkb:Q3SYL7|uniprotkb:Q5TCH8|uniprotkb:Q6V708|uniprotkb:Q9H100|uniprotkb:Q9NQM6|ensembl:ENSP00000360286|ensembl:ENSP00000379181|ensembl:ENSP00000379182|uniprotkb:A8K882 psi-mi:sox2_human(display_long)|uniprotkb:SOX2(gene name)|psi-mi:SOX2(display_short) psi-mi:rae1l_human(display_long)|uniprotkb:mRNA-associated protein mrnp 41(gene name synonym)|uniprotkb:Rae1 protein homolog(gene name synonym)|uniprotkb:RAE1(gene name)|psi-mi:RAE1(display_short)|uniprotkb:MRNP41(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Cox et al. (2012) pubmed:23667531|imex:IM-28599 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-26574619|imex:IM-28599-5 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_003097.1|dip:DIP-59913N|ensembl:ENSG00000181449(gene)|ensembl:ENST00000325404(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001649"(osteoblast differentiation)|go:"GO:0001654"(eye development)|go:"GO:0001714"(endodermal cell fate specification)|go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006325"(chromatin organization)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0009611"(response to wounding)|go:"GO:0009653"(anatomical structure morphogenesis)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0021781"(glial cell fate commitment)|go:"GO:0021983"(pituitary gland development)|go:"GO:0021984"(adenohypophysis development)|go:"GO:0022409"(positive regulation of cell-cell adhesion)|go:"GO:0030154"(cell differentiation)|go:"GO:0030900"(forebrain development)|go:"GO:0035019"(somatic stem cell population maintenance)|go:"GO:0035198"(miRNA binding)|go:"GO:0042246"(tissue regeneration)|go:"GO:0043281"(regulation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0043410"(positive regulation of MAPK cascade)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045165"(cell fate commitment)|go:"GO:0045597"(positive regulation of cell differentiation)|go:"GO:0045665"(negative regulation of neuron differentiation)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048839"(inner ear development)|go:"GO:0050680"(negative regulation of epithelial cell proliferation)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0070848"(response to growth factor)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:0097150"(neuronal stem cell population maintenance)|interpro:IPR009071(High mobility group box, HMG)|interpro:IPR022097|interpro:IPR032643|interpro:IPR036910|mint:P48431|rcsb pdb:1O4X|rcsb pdb:2LE4|rcsb pdb:6T7B|rcsb pdb:6T90|rcsb pdb:6WX7|rcsb pdb:6WX8|rcsb pdb:6WX9|rcsb pdb:6YOV|reactome:R-HSA-2892245|reactome:R-HSA-2892247|reactome:R-HSA-3769402|reactome:R-HSA-452723|reactome:R-HSA-6785807|reactome:R-HSA-8986944 refseq:NP_001015885.1|refseq:NP_003601.1|ensembl:ENSG00000101146(gene)|ensembl:ENST00000371242(transcript)|ensembl:ENST00000395840(transcript)|ensembl:ENST00000395841(transcript)|go:"GO:0001650"(fibrillar center)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005643"(nuclear pore)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006405"(RNA export from nucleus)|go:"GO:0006406"(mRNA export from nucleus)|go:"GO:0007049"(cell cycle)|go:"GO:0008017"(microtubule binding)|go:"GO:0043130"(ubiquitin binding)|go:"GO:0051301"(cell division)|go:"GO:0060236"(regulation of mitotic spindle organization)|go:"GO:0071407"(cellular response to organic cyclic compound)|go:"GO:0097431"(mitotic spindle pole)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|go:"GO:0000972"(transcription-dependent tethering of RNA polymerase II gene DNA at nuclear periphery)|interpro:IPR020472|interpro:IPR036322|interpro:IPR037631|mint:P78406|rcsb pdb:3MMY|rcsb pdb:4OWR|reactome:R-HSA-1169408|reactome:R-HSA-159227|reactome:R-HSA-159230|reactome:R-HSA-159231|reactome:R-HSA-159236|reactome:R-HSA-165054|reactome:R-HSA-168271|reactome:R-HSA-168276|reactome:R-HSA-168325|reactome:R-HSA-168333|reactome:R-HSA-170822|reactome:R-HSA-180746|reactome:R-HSA-180910|reactome:R-HSA-191859|reactome:R-HSA-3108214|reactome:R-HSA-3232142|reactome:R-HSA-3301854|reactome:R-HSA-3371453|reactome:R-HSA-4085377|reactome:R-HSA-4551638|reactome:R-HSA-4570464|interpro:IPR019775|reactome:R-HSA-4615885|reactome:R-HSA-5578749|reactome:R-HSA-5619107|reactome:R-HSA-6784531|reactome:R-HSA-9609690|reactome:R-HSA-9610379|refseq:XP_011527390.1|refseq:XP_011527391.1|refseq:XP_005260639.2|dip:DIP-41063N go:"GO:0005634"(nucleus) - - figure legend:ST2 F2A|comment:proteins identified only in our induced samples in three MudPIT analyses with the more stringent BY-adjusted significance p<0.05|dataset:Brain Disease - Neurological Diseases & Disorders|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-daoy)|taxid:9606(Homo sapiens DAOY cerebellar medulloblastoma cell line) - 2020/12/29 2020/12/29 rogid:cn8gYfKDpQc8J2ygnqny32sIyyU9606 rogid:JK4Y5p3WUcHFXBXyhhqCnDnG49c9606 rigid:6EMs5+B89Q89RCR/2S2BG6PhH9E false tandem tag:n-n - - - psi-mi:"MI:0658"(multidimensional protein identification technology) psi-mi:"MI:0658"(multidimensional protein identification technology) uniprotkb:P48431 uniprotkb:Q96DH6-2 intact:EBI-6124081|uniprotkb:Q14537|ensembl:ENSP00000323588 intact:EBI-16399707|ensembl:ENSP00000313616 psi-mi:sox2_human(display_long)|uniprotkb:SOX2(gene name)|psi-mi:SOX2(display_short) psi-mi:q96dh6-2(display_long)|uniprotkb:MSI2(gene name)|psi-mi:MSI2(display_short) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Cox et al. (2012) pubmed:23667531|imex:IM-28599 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-26574803|imex:IM-28599-7 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_003097.1|dip:DIP-59913N|ensembl:ENSG00000181449(gene)|ensembl:ENST00000325404(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001649"(osteoblast differentiation)|go:"GO:0001654"(eye development)|go:"GO:0001714"(endodermal cell fate specification)|go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006325"(chromatin organization)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0009611"(response to wounding)|go:"GO:0009653"(anatomical structure morphogenesis)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0021781"(glial cell fate commitment)|go:"GO:0021983"(pituitary gland development)|go:"GO:0021984"(adenohypophysis development)|go:"GO:0022409"(positive regulation of cell-cell adhesion)|go:"GO:0030154"(cell differentiation)|go:"GO:0030900"(forebrain development)|go:"GO:0035019"(somatic stem cell population maintenance)|go:"GO:0035198"(miRNA binding)|go:"GO:0042246"(tissue regeneration)|go:"GO:0043281"(regulation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0043410"(positive regulation of MAPK cascade)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045165"(cell fate commitment)|go:"GO:0045597"(positive regulation of cell differentiation)|go:"GO:0045665"(negative regulation of neuron differentiation)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048839"(inner ear development)|go:"GO:0050680"(negative regulation of epithelial cell proliferation)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0070848"(response to growth factor)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:0097150"(neuronal stem cell population maintenance)|interpro:IPR009071(High mobility group box, HMG)|interpro:IPR022097|interpro:IPR032643|interpro:IPR036910|mint:P48431|rcsb pdb:1O4X|rcsb pdb:2LE4|rcsb pdb:6T7B|rcsb pdb:6T90|rcsb pdb:6WX7|rcsb pdb:6WX8|rcsb pdb:6WX9|rcsb pdb:6YOV|reactome:R-HSA-2892245|reactome:R-HSA-2892247|reactome:R-HSA-3769402|reactome:R-HSA-452723|reactome:R-HSA-6785807|reactome:R-HSA-8986944 intact:EBI-2462339(isoform-parent)|ensembl:ENSG00000153944(gene)|ensembl:ENST00000322684(transcript) go:"GO:0005634"(nucleus) - - figure legend:SF1A|dataset:Brain Disease - Neurological Diseases & Disorders|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-daoy)|taxid:9606(Homo sapiens DAOY cerebellar medulloblastoma cell line) - 2020/12/29 2020/12/29 rogid:cn8gYfKDpQc8J2ygnqny32sIyyU9606 rogid:Kut4/1wOMPS3cezu5262rVjt9lw9606 rigid:2sgQuZUX65gPgUQdIN3z3NxShs8 false - - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:P48431 uniprotkb:Q96DH6-1 intact:EBI-6124081|uniprotkb:Q14537|ensembl:ENSP00000323588 intact:EBI-26574796|ensembl:ENSP00000284073|ensembl:ENSP00000502137 psi-mi:sox2_human(display_long)|uniprotkb:SOX2(gene name)|psi-mi:SOX2(display_short) psi-mi:q96dh6-1(display_long)|uniprotkb:MSI2(gene name)|psi-mi:MSI2(display_short)|uniprotkb:A(isoform synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Cox et al. (2012) pubmed:23667531|imex:IM-28599 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-26574803|imex:IM-28599-7 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_003097.1|dip:DIP-59913N|ensembl:ENSG00000181449(gene)|ensembl:ENST00000325404(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001649"(osteoblast differentiation)|go:"GO:0001654"(eye development)|go:"GO:0001714"(endodermal cell fate specification)|go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006325"(chromatin organization)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0009611"(response to wounding)|go:"GO:0009653"(anatomical structure morphogenesis)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0021781"(glial cell fate commitment)|go:"GO:0021983"(pituitary gland development)|go:"GO:0021984"(adenohypophysis development)|go:"GO:0022409"(positive regulation of cell-cell adhesion)|go:"GO:0030154"(cell differentiation)|go:"GO:0030900"(forebrain development)|go:"GO:0035019"(somatic stem cell population maintenance)|go:"GO:0035198"(miRNA binding)|go:"GO:0042246"(tissue regeneration)|go:"GO:0043281"(regulation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0043410"(positive regulation of MAPK cascade)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045165"(cell fate commitment)|go:"GO:0045597"(positive regulation of cell differentiation)|go:"GO:0045665"(negative regulation of neuron differentiation)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048839"(inner ear development)|go:"GO:0050680"(negative regulation of epithelial cell proliferation)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0070848"(response to growth factor)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:0097150"(neuronal stem cell population maintenance)|interpro:IPR009071(High mobility group box, HMG)|interpro:IPR022097|interpro:IPR032643|interpro:IPR036910|mint:P48431|rcsb pdb:1O4X|rcsb pdb:2LE4|rcsb pdb:6T7B|rcsb pdb:6T90|rcsb pdb:6WX7|rcsb pdb:6WX8|rcsb pdb:6WX9|rcsb pdb:6YOV|reactome:R-HSA-2892245|reactome:R-HSA-2892247|reactome:R-HSA-3769402|reactome:R-HSA-452723|reactome:R-HSA-6785807|reactome:R-HSA-8986944 intact:EBI-2462339(isoform-parent)|ensembl:ENSG00000153944(gene)|ensembl:ENST00000284073(transcript)|ensembl:ENST00000674964(transcript) go:"GO:0005634"(nucleus) - - figure legend:SF1A|dataset:Brain Disease - Neurological Diseases & Disorders|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-daoy)|taxid:9606(Homo sapiens DAOY cerebellar medulloblastoma cell line) - 2020/12/29 2020/12/29 rogid:cn8gYfKDpQc8J2ygnqny32sIyyU9606 rogid:/tSHeNbYwUTw4kGlF3LQw+5OVjs9606 rigid:2sgQuZUX65gPgUQdIN3z3NxShs8 false - - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:P48431 uniprotkb:Q93009 intact:EBI-6124081|uniprotkb:Q14537|ensembl:ENSP00000323588 intact:EBI-302474|uniprotkb:A6NMY8|intact:EBI-28988230|ensembl:ENSP00000343535|uniprotkb:B7Z815|uniprotkb:H0Y3G8 psi-mi:sox2_human(display_long)|uniprotkb:SOX2(gene name)|psi-mi:SOX2(display_short) psi-mi:ubp7_human(display_long)|uniprotkb:USP7(gene name)|psi-mi:USP7(display_short)|uniprotkb:HAUSP(gene name synonym)|uniprotkb:Ubiquitin thioesterase 7(gene name synonym)|uniprotkb:Ubiquitin-specific-processing protease 7(gene name synonym)|uniprotkb:Deubiquitinating enzyme 7(gene name synonym)|uniprotkb:Herpesvirus-associated ubiquitin-specific protease(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Cox et al. (2012) pubmed:23667531|imex:IM-28599 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-26574803|imex:IM-28599-7 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_003097.1|dip:DIP-59913N|ensembl:ENSG00000181449(gene)|ensembl:ENST00000325404(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001649"(osteoblast differentiation)|go:"GO:0001654"(eye development)|go:"GO:0001714"(endodermal cell fate specification)|go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006325"(chromatin organization)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0009611"(response to wounding)|go:"GO:0009653"(anatomical structure morphogenesis)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0021781"(glial cell fate commitment)|go:"GO:0021983"(pituitary gland development)|go:"GO:0021984"(adenohypophysis development)|go:"GO:0022409"(positive regulation of cell-cell adhesion)|go:"GO:0030154"(cell differentiation)|go:"GO:0030900"(forebrain development)|go:"GO:0035019"(somatic stem cell population maintenance)|go:"GO:0035198"(miRNA binding)|go:"GO:0042246"(tissue regeneration)|go:"GO:0043281"(regulation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0043410"(positive regulation of MAPK cascade)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045165"(cell fate commitment)|go:"GO:0045597"(positive regulation of cell differentiation)|go:"GO:0045665"(negative regulation of neuron differentiation)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048839"(inner ear development)|go:"GO:0050680"(negative regulation of epithelial cell proliferation)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0070848"(response to growth factor)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:0097150"(neuronal stem cell population maintenance)|interpro:IPR009071(High mobility group box, HMG)|interpro:IPR022097|interpro:IPR032643|interpro:IPR036910|mint:P48431|rcsb pdb:1O4X|rcsb pdb:2LE4|rcsb pdb:6T7B|rcsb pdb:6T90|rcsb pdb:6WX7|rcsb pdb:6WX8|rcsb pdb:6WX9|rcsb pdb:6YOV|reactome:R-HSA-2892245|reactome:R-HSA-2892247|reactome:R-HSA-3769402|reactome:R-HSA-452723|reactome:R-HSA-6785807|reactome:R-HSA-8986944 rcsb pdb:4PYZ|rcsb pdb:4WPH|rcsb pdb:4WPI|rcsb pdb:4YOC|rcsb pdb:4YSI|rcsb pdb:4Z96|rcsb pdb:4Z97|rcsb pdb:5C56|rcsb pdb:5C6D|rcsb pdb:5FWI|rcsb pdb:5GG4|rcsb pdb:5J7T|rcsb pdb:5JTJ|rcsb pdb:5JTV|rcsb pdb:5KYB|rcsb pdb:4M5X|rcsb pdb:5KYC|rcsb pdb:5KYD|rcsb pdb:5KYE|rcsb pdb:5KYF|interpro:IPR029346|interpro:IPR038765|mint:Q93009|rcsb pdb:1NB8|rcsb pdb:1NBF|rcsb pdb:1YY6|rcsb pdb:1YZE|rcsb pdb:2F1W|rcsb pdb:2F1X|rcsb pdb:2F1Y|rcsb pdb:2F1Z|rcsb pdb:2FOJ|rcsb pdb:2FOO|rcsb pdb:2FOP|rcsb pdb:2KVR|rcsb pdb:2XXN|rcsb pdb:2YLM|rcsb pdb:3MQR|rcsb pdb:3MQS|rcsb pdb:4JJQ|rcsb pdb:4KG9|rcsb pdb:4M5W|go:"GO:0006283"(transcription-coupled nucleotide-excision repair)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008134"(transcription factor binding)|go:"GO:0010216"(maintenance of DNA methylation)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0016579"(protein deubiquitination)|go:"GO:0016604"(nuclear body)|go:"GO:0016605"(PML body)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0031647"(regulation of protein stability)|go:"GO:0032088"(negative regulation of NF-kappaB transcription factor activity)|go:"GO:0032435"(negative regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035520"(monoubiquitinated protein deubiquitination)|go:"GO:0035616"(histone H2B conserved C-terminal lysine deubiquitination)|go:"GO:0042752"(regulation of circadian rhythm)|go:"GO:0048511"(rhythmic process)|go:"GO:0050821"(protein stabilization)|go:"GO:0051090"(regulation of DNA-binding transcription factor activity)|go:"GO:0070536"(protein K63-linked deubiquitination)|go:"GO:0101005"(deubiquitinase activity)|go:"GO:1901537"(positive regulation of DNA demethylation)|go:"GO:1901796"(regulation of signal transduction by p53 class mediator)|go:"GO:1904353"(regulation of telomere capping)|go:"GO:1905279"(regulation of retrograde transport, endosome to Golgi)|go:"GO:1990380"(Lys48-specific deubiquitinase activity)|interpro:IPR001394(Peptidase C19, ubiquitin carboxyl-terminal hydrolase 2)|interpro:IPR002083(MATH)|interpro:IPR008974(TRAF-like)|interpro:IPR018200|interpro:IPR024729|interpro:IPR028889|ensembl:ENSG00000187555(gene)|ensembl:ENST00000344836(transcript)|go:"GO:0002039"(p53 binding)|go:"GO:0004197"(cysteine-type endopeptidase activity)|go:"GO:0004843"(thiol-dependent deubiquitinase)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005694"(chromosome)|go:"GO:0005829"(cytosol)|go:"GO:0006111"(regulation of gluconeogenesis)|rcsb pdb:5N9R|rcsb pdb:5N9T|rcsb pdb:5NGE|rcsb pdb:5NGF|rcsb pdb:5UQV|rcsb pdb:5UQX|rcsb pdb:5VS6|rcsb pdb:5VSB|rcsb pdb:5VSK|rcsb pdb:5WHC|rcsb pdb:6F5H|rcsb pdb:6M1K|rcsb pdb:6P5L|rcsb pdb:6VN2|rcsb pdb:6VN3|rcsb pdb:6VN4|rcsb pdb:6VN5|rcsb pdb:6VN6|rcsb pdb:7CM2|reactome:R-HSA-5689880|reactome:R-HSA-6781823|reactome:R-HSA-6781827|reactome:R-HSA-6782135|reactome:R-HSA-6782210|reactome:R-HSA-6804757|reactome:R-HSA-8866652|reactome:R-HSA-8948747|refseq:NP_001273386.1|refseq:NP_003461.2|refseq:NP_001308787.1|ensembl:ENSP00000343535|ensembl:ENST00000381886|ensembl:ENSP00000371310|dip:DIP-29053N go:"GO:0005634"(nucleus) - - figure legend:SF1A|dataset:Brain Disease - Neurological Diseases & Disorders|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-daoy)|taxid:9606(Homo sapiens DAOY cerebellar medulloblastoma cell line) - 2020/12/29 2020/12/29 rogid:cn8gYfKDpQc8J2ygnqny32sIyyU9606 rogid:V+PXXBRM2zwlGQaeFiyjaQ9yf+A9606 rigid:2sgQuZUX65gPgUQdIN3z3NxShs8 false - - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:Q93009 uniprotkb:P48431 intact:EBI-302474|uniprotkb:A6NMY8|intact:EBI-28988230|ensembl:ENSP00000343535|uniprotkb:B7Z815|uniprotkb:H0Y3G8 intact:EBI-6124081|uniprotkb:Q14537|ensembl:ENSP00000323588 psi-mi:ubp7_human(display_long)|uniprotkb:USP7(gene name)|psi-mi:USP7(display_short)|uniprotkb:HAUSP(gene name synonym)|uniprotkb:Ubiquitin thioesterase 7(gene name synonym)|uniprotkb:Ubiquitin-specific-processing protease 7(gene name synonym)|uniprotkb:Deubiquitinating enzyme 7(gene name synonym)|uniprotkb:Herpesvirus-associated ubiquitin-specific protease(gene name synonym) psi-mi:sox2_human(display_long)|uniprotkb:SOX2(gene name)|psi-mi:SOX2(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Cox et al. (2012) pubmed:23667531|imex:IM-28599 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-26574809|imex:IM-28599-9 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) rcsb pdb:4PYZ|rcsb pdb:4WPH|rcsb pdb:4WPI|rcsb pdb:4YOC|rcsb pdb:4YSI|rcsb pdb:4Z96|rcsb pdb:4Z97|rcsb pdb:5C56|rcsb pdb:5C6D|rcsb pdb:5FWI|rcsb pdb:5GG4|rcsb pdb:5J7T|rcsb pdb:5JTJ|rcsb pdb:5JTV|rcsb pdb:5KYB|rcsb pdb:4M5X|rcsb pdb:5KYC|rcsb pdb:5KYD|rcsb pdb:5KYE|rcsb pdb:5KYF|interpro:IPR029346|interpro:IPR038765|mint:Q93009|rcsb pdb:1NB8|rcsb pdb:1NBF|rcsb pdb:1YY6|rcsb pdb:1YZE|rcsb pdb:2F1W|rcsb pdb:2F1X|rcsb pdb:2F1Y|rcsb pdb:2F1Z|rcsb pdb:2FOJ|rcsb pdb:2FOO|rcsb pdb:2FOP|rcsb pdb:2KVR|rcsb pdb:2XXN|rcsb pdb:2YLM|rcsb pdb:3MQR|rcsb pdb:3MQS|rcsb pdb:4JJQ|rcsb pdb:4KG9|rcsb pdb:4M5W|go:"GO:0006283"(transcription-coupled nucleotide-excision repair)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008134"(transcription factor binding)|go:"GO:0010216"(maintenance of DNA methylation)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0016579"(protein deubiquitination)|go:"GO:0016604"(nuclear body)|go:"GO:0016605"(PML body)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0031647"(regulation of protein stability)|go:"GO:0032088"(negative regulation of NF-kappaB transcription factor activity)|go:"GO:0032435"(negative regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035520"(monoubiquitinated protein deubiquitination)|go:"GO:0035616"(histone H2B conserved C-terminal lysine deubiquitination)|go:"GO:0042752"(regulation of circadian rhythm)|go:"GO:0048511"(rhythmic process)|go:"GO:0050821"(protein stabilization)|go:"GO:0051090"(regulation of DNA-binding transcription factor activity)|go:"GO:0070536"(protein K63-linked deubiquitination)|go:"GO:0101005"(deubiquitinase activity)|go:"GO:1901537"(positive regulation of DNA demethylation)|go:"GO:1901796"(regulation of signal transduction by p53 class mediator)|go:"GO:1904353"(regulation of telomere capping)|go:"GO:1905279"(regulation of retrograde transport, endosome to Golgi)|go:"GO:1990380"(Lys48-specific deubiquitinase activity)|interpro:IPR001394(Peptidase C19, ubiquitin carboxyl-terminal hydrolase 2)|interpro:IPR002083(MATH)|interpro:IPR008974(TRAF-like)|interpro:IPR018200|interpro:IPR024729|interpro:IPR028889|ensembl:ENSG00000187555(gene)|ensembl:ENST00000344836(transcript)|go:"GO:0002039"(p53 binding)|go:"GO:0004197"(cysteine-type endopeptidase activity)|go:"GO:0004843"(thiol-dependent deubiquitinase)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005694"(chromosome)|go:"GO:0005829"(cytosol)|go:"GO:0006111"(regulation of gluconeogenesis)|rcsb pdb:5N9R|rcsb pdb:5N9T|rcsb pdb:5NGE|rcsb pdb:5NGF|rcsb pdb:5UQV|rcsb pdb:5UQX|rcsb pdb:5VS6|rcsb pdb:5VSB|rcsb pdb:5VSK|rcsb pdb:5WHC|rcsb pdb:6F5H|rcsb pdb:6M1K|rcsb pdb:6P5L|rcsb pdb:6VN2|rcsb pdb:6VN3|rcsb pdb:6VN4|rcsb pdb:6VN5|rcsb pdb:6VN6|rcsb pdb:7CM2|reactome:R-HSA-5689880|reactome:R-HSA-6781823|reactome:R-HSA-6781827|reactome:R-HSA-6782135|reactome:R-HSA-6782210|reactome:R-HSA-6804757|reactome:R-HSA-8866652|reactome:R-HSA-8948747|refseq:NP_001273386.1|refseq:NP_003461.2|refseq:NP_001308787.1|ensembl:ENSP00000343535|ensembl:ENST00000381886|ensembl:ENSP00000371310|dip:DIP-29053N refseq:NP_003097.1|dip:DIP-59913N|ensembl:ENSG00000181449(gene)|ensembl:ENST00000325404(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001649"(osteoblast differentiation)|go:"GO:0001654"(eye development)|go:"GO:0001714"(endodermal cell fate specification)|go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006325"(chromatin organization)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0009611"(response to wounding)|go:"GO:0009653"(anatomical structure morphogenesis)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0021781"(glial cell fate commitment)|go:"GO:0021983"(pituitary gland development)|go:"GO:0021984"(adenohypophysis development)|go:"GO:0022409"(positive regulation of cell-cell adhesion)|go:"GO:0030154"(cell differentiation)|go:"GO:0030900"(forebrain development)|go:"GO:0035019"(somatic stem cell population maintenance)|go:"GO:0035198"(miRNA binding)|go:"GO:0042246"(tissue regeneration)|go:"GO:0043281"(regulation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0043410"(positive regulation of MAPK cascade)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045165"(cell fate commitment)|go:"GO:0045597"(positive regulation of cell differentiation)|go:"GO:0045665"(negative regulation of neuron differentiation)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048839"(inner ear development)|go:"GO:0050680"(negative regulation of epithelial cell proliferation)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0070848"(response to growth factor)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:0097150"(neuronal stem cell population maintenance)|interpro:IPR009071(High mobility group box, HMG)|interpro:IPR022097|interpro:IPR032643|interpro:IPR036910|mint:P48431|rcsb pdb:1O4X|rcsb pdb:2LE4|rcsb pdb:6T7B|rcsb pdb:6T90|rcsb pdb:6WX7|rcsb pdb:6WX8|rcsb pdb:6WX9|rcsb pdb:6YOV|reactome:R-HSA-2892245|reactome:R-HSA-2892247|reactome:R-HSA-3769402|reactome:R-HSA-452723|reactome:R-HSA-6785807|reactome:R-HSA-8986944 go:"GO:0005634"(nucleus) - - figure legend:SF1B|dataset:Brain Disease - Neurological Diseases & Disorders|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/12/29 2020/12/29 rogid:V+PXXBRM2zwlGQaeFiyjaQ9yf+A9606 rogid:cn8gYfKDpQc8J2ygnqny32sIyyU9606 rigid:tEYKd845NaNR6KB/Cc6AjDupeQQ false - flag tag:n-n - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:P48431 uniprotkb:Q96DH6 intact:EBI-6124081|uniprotkb:Q14537|ensembl:ENSP00000323588 intact:EBI-2462339|uniprotkb:Q7Z6M7|uniprotkb:Q8N9T4|ensembl:ENSP00000284073|ensembl:ENSP00000502137 psi-mi:sox2_human(display_long)|uniprotkb:SOX2(gene name)|psi-mi:SOX2(display_short) psi-mi:msi2h_human(display_long)|uniprotkb:MSI2(gene name)|psi-mi:MSI2(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Cox et al. (2012) pubmed:23667531|imex:IM-28599 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-26574819|imex:IM-28599-11 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_003097.1|dip:DIP-59913N|ensembl:ENSG00000181449(gene)|ensembl:ENST00000325404(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001649"(osteoblast differentiation)|go:"GO:0001654"(eye development)|go:"GO:0001714"(endodermal cell fate specification)|go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006325"(chromatin organization)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0009611"(response to wounding)|go:"GO:0009653"(anatomical structure morphogenesis)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0021781"(glial cell fate commitment)|go:"GO:0021983"(pituitary gland development)|go:"GO:0021984"(adenohypophysis development)|go:"GO:0022409"(positive regulation of cell-cell adhesion)|go:"GO:0030154"(cell differentiation)|go:"GO:0030900"(forebrain development)|go:"GO:0035019"(somatic stem cell population maintenance)|go:"GO:0035198"(miRNA binding)|go:"GO:0042246"(tissue regeneration)|go:"GO:0043281"(regulation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0043410"(positive regulation of MAPK cascade)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045165"(cell fate commitment)|go:"GO:0045597"(positive regulation of cell differentiation)|go:"GO:0045665"(negative regulation of neuron differentiation)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048839"(inner ear development)|go:"GO:0050680"(negative regulation of epithelial cell proliferation)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0070848"(response to growth factor)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:0097150"(neuronal stem cell population maintenance)|interpro:IPR009071(High mobility group box, HMG)|interpro:IPR022097|interpro:IPR032643|interpro:IPR036910|mint:P48431|rcsb pdb:1O4X|rcsb pdb:2LE4|rcsb pdb:6T7B|rcsb pdb:6T90|rcsb pdb:6WX7|rcsb pdb:6WX8|rcsb pdb:6WX9|rcsb pdb:6YOV|reactome:R-HSA-2892245|reactome:R-HSA-2892247|reactome:R-HSA-3769402|reactome:R-HSA-452723|reactome:R-HSA-6785807|reactome:R-HSA-8986944 refseq:NP_620412.1|refseq:NP_733839.1|ensembl:ENSG00000153944(gene)|ensembl:ENST00000284073(transcript)|ensembl:ENST00000674964(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005844"(polysome)|go:"GO:0008266"("poly(U) RNA binding")|go:"GO:0042802"(identical protein binding)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0048864"(stem cell development)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR034126|interpro:IPR034130|interpro:IPR035979|mint:Q96DH6|rcsb pdb:6C8U|rcsb pdb:6DBP|rcsb pdb:6NTY|reactome:R-HSA-9013418 go:"GO:0005634"(nucleus) - - figure legend:SF1C|dataset:Brain Disease - Neurological Diseases & Disorders|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen) - 2020/12/29 2020/12/29 rogid:cn8gYfKDpQc8J2ygnqny32sIyyU9606 rogid:/tSHeNbYwUTw4kGlF3LQw+5OVjs9606 rigid:SXPd98nY/ovjQb+4xCmSwtWisY0 false - flag tag:?-? - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot)