#ID(s) interactor A	ID(s) interactor B	Alt. ID(s) interactor A	Alt. ID(s) interactor B	Alias(es) interactor A	Alias(es) interactor B	Interaction detection method(s)	Publication 1st author(s)	Publication Identifier(s)	Taxid interactor A	Taxid interactor B	Interaction type(s)	Source database(s)	Interaction identifier(s)	Confidence value(s)	Expansion method(s)	Biological role(s) interactor A	Biological role(s) interactor B	Experimental role(s) interactor A	Experimental role(s) interactor B	Type(s) interactor A	Type(s) interactor B	Xref(s) interactor A	Xref(s) interactor B	Interaction Xref(s)	Annotation(s) interactor A	Annotation(s) interactor B	Interaction annotation(s)	Host organism(s)	Interaction parameter(s)	Creation date	Update date	Checksum(s) interactor A	Checksum(s) interactor B	Interaction Checksum(s)	Negative	Feature(s) interactor A	Feature(s) interactor B	Stoichiometry(s) interactor A	Stoichiometry(s) interactor B	Identification method participant A	Identification method participant B
intact:EBI-25595699	intact:EBI-25470264	rnacentral:URS0000483184_9606	ensembl:ENST00000403681	psi-mi:hsa-mir-33a-5p(display_short)|psi-mi:EBI-25595699(display_long)	psi-mi:mrna_hmga2(display_short)|psi-mi:EBI-25470264(display_long)	psi-mi:"MI:2285"(miRNA interference luciferase reporter assay)	Rice et al. (2013)	imex:IM-27963|pubmed:23625920	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-25595696|imex:IM-27963-1	-	-	psi-mi:"MI:2274"(regulator)	psi-mi:"MI:2275"(regulator target)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:2204"(micro rna)	psi-mi:"MI:0324"(messenger rna)	-	ensembl:ENSG00000149948(see-also)	go:"GO:1903231"(mRNA binding involved in posttranscriptional gene silencing)	-	-	figure legend:Fig 7 A B|causality statement:down-regulates quantity by destabilization|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-nci_h1299)|taxid:9606(Homo sapiens)	-	2020/05/06	2020/05/06	-	-	-	false	-	mutation decreasing interaction:1732-1738,2788-2794|mutation decreasing interaction:2788-2794|mutation with no effect:3089-3094|mutation decreasing interaction:1732-1738,3089-3094|luciferase tag:0-0|mutation decreasing interaction:1732-1738,2788-2794,3089-3094|mutation decreasing interaction:1732-1738	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:1220"(tag visualisation by luciferase assay)
uniprotkb:P43699	ensembl:ENSG00000198911	intact:EBI-1391923|uniprotkb:O14954|uniprotkb:O14955|uniprotkb:Q9BRJ8|uniprotkb:Q7KZF6|uniprotkb:D3DSA3|ensembl:ENSP00000428341|ensembl:ENSP00000429607	intact:EBI-25596415	psi-mi:nkx21_human(display_long)|uniprotkb:NKX2-1(gene name)|psi-mi:NKX2-1(display_short)|uniprotkb:TITF1(gene name synonym)|uniprotkb:NKX2A(gene name synonym)|uniprotkb:TTF1(gene name synonym)|uniprotkb:Homeobox protein NK-2 homolog A(gene name synonym)|uniprotkb:Thyroid transcription factor 1(gene name synonym)|uniprotkb:Thyroid nuclear factor 1(gene name synonym)|uniprotkb:Thyroid-specific enhancer-binding protein(gene name synonym)	uniprotkb:SREBF2(gene name)|psi-mi:SREBF2(display_short)|uniprotkb:BHLHD2(gene name synonym)|uniprotkb:SREBP2(gene name synonym)|ensembl:srbp2_human_gene(shortlabel)|psi-mi:ENSG00000198911(display_long)	psi-mi:"MI:0402"(chromatin immunoprecipitation assay)	Rice et al. (2013)	imex:IM-27963|pubmed:23625920	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-25596406|imex:IM-27963-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0250"(gene)	refseq:NP_001073136.1|refseq:NP_003308.1|ensembl:ENSG00000136352(gene)|ensembl:ENST00000498187(transcript)|ensembl:ENST00000518149(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001161"(intronic transcription regulatory region sequence-specific DNA binding)|go:"GO:0001764"(neuron migration)|go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006644"(phospholipid metabolic process)|go:"GO:0007411"(axon guidance)|go:"GO:0007420"(brain development)|go:"GO:0007492"(endoderm development)|go:"GO:0007626"(locomotory behavior)|go:"GO:0009725"(response to hormone)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010719"(negative regulation of epithelial to mesenchymal transition)|go:"GO:0019899"(enzyme binding)|go:"GO:0021759"(globus pallidus development)|go:"GO:0021766"(hippocampus development)|go:"GO:0021795"(cerebral cortex cell migration)|go:"GO:0021798"(forebrain dorsal/ventral pattern formation)|go:"GO:0021877"(forebrain neuron fate commitment)|go:"GO:0021892"(cerebral cortex GABAergic interneuron differentiation)|go:"GO:0021983"(pituitary gland development)|go:"GO:0030154"(cell differentiation)|go:"GO:0030324"(lung development)|go:"GO:0030336"(negative regulation of cell migration)|go:"GO:0030512"(negative regulation of transforming growth factor beta receptor signaling pathway)|go:"GO:0030878"(thyroid gland development)|go:"GO:0030900"(forebrain development)|go:"GO:0031128"(developmental induction)|go:"GO:0033327"(Leydig cell differentiation)|go:"GO:0042753"(positive regulation of circadian rhythm)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048511"(rhythmic process)|go:"GO:0048646"(anatomical structure formation involved in morphogenesis)|go:"GO:0048709"(oligodendrocyte differentiation)|go:"GO:0060430"(lung saccule development)|go:"GO:0060441"(epithelial tube branching involved in lung morphogenesis)|go:"GO:0060486"(club cell differentiation)|go:"GO:0060510"(type II pneumocyte differentiation)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|interpro:IPR001356(Homeobox)|interpro:IPR009057(Homeodomain-like)|interpro:IPR017970|interpro:IPR020479	refseq:NP_004590.2	-	-	-	figure legend:Fig 4 D|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-nci_h441)|taxid:9606(Homo sapiens)	-	2020/05/06	2020/05/08	rogid:bl+uMAW9z5GF1R21A7VpncC1UR89606	-	-	false	-	sufficient binding region:?-?	-	-	psi-mi:"MI:1195"(quantitative pcr)	psi-mi:"MI:1195"(quantitative pcr)
uniprotkb:P43699	ensembl:ENSG00000106771	intact:EBI-1391923|uniprotkb:O14954|uniprotkb:O14955|uniprotkb:Q9BRJ8|uniprotkb:Q7KZF6|uniprotkb:D3DSA3|ensembl:ENSP00000428341|ensembl:ENSP00000429607	intact:EBI-25596409	psi-mi:nkx21_human(display_long)|uniprotkb:NKX2-1(gene name)|psi-mi:NKX2-1(display_short)|uniprotkb:TITF1(gene name synonym)|uniprotkb:NKX2A(gene name synonym)|uniprotkb:TTF1(gene name synonym)|uniprotkb:Homeobox protein NK-2 homolog A(gene name synonym)|uniprotkb:Thyroid transcription factor 1(gene name synonym)|uniprotkb:Thyroid nuclear factor 1(gene name synonym)|uniprotkb:Thyroid-specific enhancer-binding protein(gene name synonym)	uniprotkb:TMEM245(gene name)|psi-mi:TMEM245(display_short)|uniprotkb:C9orf5(gene name synonym)|ensembl:tm245_human_gene(shortlabel)|psi-mi:ENSG00000106771(display_long)	psi-mi:"MI:0402"(chromatin immunoprecipitation assay)	Rice et al. (2013)	imex:IM-27963|pubmed:23625920	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-25596406|imex:IM-27963-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0250"(gene)	refseq:NP_001073136.1|refseq:NP_003308.1|ensembl:ENSG00000136352(gene)|ensembl:ENST00000498187(transcript)|ensembl:ENST00000518149(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001161"(intronic transcription regulatory region sequence-specific DNA binding)|go:"GO:0001764"(neuron migration)|go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006644"(phospholipid metabolic process)|go:"GO:0007411"(axon guidance)|go:"GO:0007420"(brain development)|go:"GO:0007492"(endoderm development)|go:"GO:0007626"(locomotory behavior)|go:"GO:0009725"(response to hormone)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010719"(negative regulation of epithelial to mesenchymal transition)|go:"GO:0019899"(enzyme binding)|go:"GO:0021759"(globus pallidus development)|go:"GO:0021766"(hippocampus development)|go:"GO:0021795"(cerebral cortex cell migration)|go:"GO:0021798"(forebrain dorsal/ventral pattern formation)|go:"GO:0021877"(forebrain neuron fate commitment)|go:"GO:0021892"(cerebral cortex GABAergic interneuron differentiation)|go:"GO:0021983"(pituitary gland development)|go:"GO:0030154"(cell differentiation)|go:"GO:0030324"(lung development)|go:"GO:0030336"(negative regulation of cell migration)|go:"GO:0030512"(negative regulation of transforming growth factor beta receptor signaling pathway)|go:"GO:0030878"(thyroid gland development)|go:"GO:0030900"(forebrain development)|go:"GO:0031128"(developmental induction)|go:"GO:0033327"(Leydig cell differentiation)|go:"GO:0042753"(positive regulation of circadian rhythm)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048511"(rhythmic process)|go:"GO:0048646"(anatomical structure formation involved in morphogenesis)|go:"GO:0048709"(oligodendrocyte differentiation)|go:"GO:0060430"(lung saccule development)|go:"GO:0060441"(epithelial tube branching involved in lung morphogenesis)|go:"GO:0060486"(club cell differentiation)|go:"GO:0060510"(type II pneumocyte differentiation)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|interpro:IPR001356(Homeobox)|interpro:IPR009057(Homeodomain-like)|interpro:IPR017970|interpro:IPR020479	refseq:NP_114401.2	-	-	-	figure legend:Fig 4 D|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-nci_h441)|taxid:9606(Homo sapiens)	-	2020/05/06	2020/05/08	rogid:bl+uMAW9z5GF1R21A7VpncC1UR89606	-	-	false	-	sufficient binding region:?-?	-	-	psi-mi:"MI:1195"(quantitative pcr)	psi-mi:"MI:1195"(quantitative pcr)