#ID(s) interactor A ID(s) interactor B Alt. ID(s) interactor A Alt. ID(s) interactor B Alias(es) interactor A Alias(es) interactor B Interaction detection method(s) Publication 1st author(s) Publication Identifier(s) Taxid interactor A Taxid interactor B Interaction type(s) Source database(s) Interaction identifier(s) Confidence value(s) Expansion method(s) Biological role(s) interactor A Biological role(s) interactor B Experimental role(s) interactor A Experimental role(s) interactor B Type(s) interactor A Type(s) interactor B Xref(s) interactor A Xref(s) interactor B Interaction Xref(s) Annotation(s) interactor A Annotation(s) interactor B Interaction annotation(s) Host organism(s) Interaction parameter(s) Creation date Update date Checksum(s) interactor A Checksum(s) interactor B Interaction Checksum(s) Negative Feature(s) interactor A Feature(s) interactor B Stoichiometry(s) interactor A Stoichiometry(s) interactor B Identification method participant A Identification method participant B chebi:"CHEBI:17526" uniprotkb:Q9BXB5 intact:EBI-2465282 intact:EBI-2511286|ensembl:ENSP00000379804|uniprotkb:Q9BTU5|uniprotkb:B4E212 psi-mi:pi4p(display_short)|psi-mi:"CHEBI:17526"(display_long) psi-mi:osb10_human(display_long)|uniprotkb:OSBPL10(gene name)|psi-mi:OSBPL10(display_short)|uniprotkb:ORP10(gene name synonym)|uniprotkb:OSBP9(gene name synonym) psi-mi:"MI:0049"(filter binding) Nissilä et al. (2012) imex:IM-28060|pubmed:22906437 taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0486"(UniProt) intact:EBI-25437474|imex:IM-28060-21 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0328"(small molecule) psi-mi:"MI:0326"(protein) - ensembl:ENSG00000144645(gene)|ensembl:ENST00000396556(transcript)|go:"GO:0001786"(phosphatidylserine binding)|go:"GO:0005548"(phospholipid transporter activity)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0015248"(sterol transporter activity)|go:"GO:0015485"(cholesterol binding)|go:"GO:0016020"(membrane)|go:"GO:0032934"(sterol binding)|go:"GO:0036150"(phosphatidylserine acyl-chain remodeling)|go:"GO:0043231"(intracellular membrane-bounded organelle)|interpro:IPR000648(Oxysterol-binding protein)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR018494|interpro:IPR037239|interpro:IPR041680|reactome:R-HSA-1482801|refseq:NP_001167531.1|refseq:NP_060254.2 - - - figure legend:Fig. 1A|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2020/02/27 2020/06/12 - rogid:1vbWq9QaTg7Nm56KJy7HKUoxWj49606 - false - sufficient binding region:306-764|sufficient binding region:70-176(IPR001849)|glutathione s tranferase tag:?-? - - psi-mi:"MI:0421"(identification by antibody) psi-mi:"MI:0421"(identification by antibody) chebi:"CHEBI:17283" uniprotkb:Q9BXB5 intact:EBI-1257113 intact:EBI-2511286|ensembl:ENSP00000379804|uniprotkb:Q9BTU5|uniprotkb:B4E212 psi-mi:pi3p(display_short)|psi-mi:"CHEBI:17283"(display_long) psi-mi:osb10_human(display_long)|uniprotkb:OSBPL10(gene name)|psi-mi:OSBPL10(display_short)|uniprotkb:ORP10(gene name synonym)|uniprotkb:OSBP9(gene name synonym) psi-mi:"MI:0049"(filter binding) Nissilä et al. (2012) imex:IM-28060|pubmed:22906437 taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0486"(UniProt) intact:EBI-25437483|imex:IM-28060-1 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0328"(small molecule) psi-mi:"MI:0326"(protein) - ensembl:ENSG00000144645(gene)|ensembl:ENST00000396556(transcript)|go:"GO:0001786"(phosphatidylserine binding)|go:"GO:0005548"(phospholipid transporter activity)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0015248"(sterol transporter activity)|go:"GO:0015485"(cholesterol binding)|go:"GO:0016020"(membrane)|go:"GO:0032934"(sterol binding)|go:"GO:0036150"(phosphatidylserine acyl-chain remodeling)|go:"GO:0043231"(intracellular membrane-bounded organelle)|interpro:IPR000648(Oxysterol-binding protein)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR018494|interpro:IPR037239|interpro:IPR041680|reactome:R-HSA-1482801|refseq:NP_001167531.1|refseq:NP_060254.2 - - - figure legend:Fig. 1A|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2020/02/27 2020/06/12 - rogid:1vbWq9QaTg7Nm56KJy7HKUoxWj49606 - false - sufficient binding region:306-764|sufficient binding region:70-176(IPR001849)|glutathione s tranferase tag:?-? - - psi-mi:"MI:0421"(identification by antibody) psi-mi:"MI:0421"(identification by antibody) chebi:"CHEBI:16152" uniprotkb:Q9BXB5 intact:EBI-2296297 intact:EBI-2511286|ensembl:ENSP00000379804|uniprotkb:Q9BTU5|uniprotkb:B4E212 psi-mi:1-phosphatidyl-1d-myo-inositol 3,4-bisphosphate(display_short)|psi-mi:"CHEBI:16152"(display_long) psi-mi:osb10_human(display_long)|uniprotkb:OSBPL10(gene name)|psi-mi:OSBPL10(display_short)|uniprotkb:ORP10(gene name synonym)|uniprotkb:OSBP9(gene name synonym) psi-mi:"MI:0049"(filter binding) Nissilä et al. (2012) imex:IM-28060|pubmed:22906437 taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0486"(UniProt) intact:EBI-25437492|imex:IM-28060-3 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0328"(small molecule) psi-mi:"MI:0326"(protein) - ensembl:ENSG00000144645(gene)|ensembl:ENST00000396556(transcript)|go:"GO:0001786"(phosphatidylserine binding)|go:"GO:0005548"(phospholipid transporter activity)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0015248"(sterol transporter activity)|go:"GO:0015485"(cholesterol binding)|go:"GO:0016020"(membrane)|go:"GO:0032934"(sterol binding)|go:"GO:0036150"(phosphatidylserine acyl-chain remodeling)|go:"GO:0043231"(intracellular membrane-bounded organelle)|interpro:IPR000648(Oxysterol-binding protein)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR018494|interpro:IPR037239|interpro:IPR041680|reactome:R-HSA-1482801|refseq:NP_001167531.1|refseq:NP_060254.2 - - - figure legend:Fig. 1A|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2020/02/27 2020/06/12 - rogid:1vbWq9QaTg7Nm56KJy7HKUoxWj49606 - false - sufficient binding region:70-176(IPR001849)|glutathione s tranferase tag:?-? - - psi-mi:"MI:0421"(identification by antibody) psi-mi:"MI:0421"(identification by antibody) chebi:"CHEBI:16851" uniprotkb:Q9BXB5 intact:EBI-1257121 intact:EBI-2511286|ensembl:ENSP00000379804|uniprotkb:Q9BTU5|uniprotkb:B4E212 psi-mi:1-phosphatidyl-1d-myo-inositol 3,5-bisphosphate(display_short)|psi-mi:"CHEBI:16851"(display_long) psi-mi:osb10_human(display_long)|uniprotkb:OSBPL10(gene name)|psi-mi:OSBPL10(display_short)|uniprotkb:ORP10(gene name synonym)|uniprotkb:OSBP9(gene name synonym) psi-mi:"MI:0049"(filter binding) Nissilä et al. (2012) imex:IM-28060|pubmed:22906437 taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0486"(UniProt) intact:EBI-25437501|imex:IM-28060-23 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0328"(small molecule) psi-mi:"MI:0326"(protein) - ensembl:ENSG00000144645(gene)|ensembl:ENST00000396556(transcript)|go:"GO:0001786"(phosphatidylserine binding)|go:"GO:0005548"(phospholipid transporter activity)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0015248"(sterol transporter activity)|go:"GO:0015485"(cholesterol binding)|go:"GO:0016020"(membrane)|go:"GO:0032934"(sterol binding)|go:"GO:0036150"(phosphatidylserine acyl-chain remodeling)|go:"GO:0043231"(intracellular membrane-bounded organelle)|interpro:IPR000648(Oxysterol-binding protein)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR018494|interpro:IPR037239|interpro:IPR041680|reactome:R-HSA-1482801|refseq:NP_001167531.1|refseq:NP_060254.2 - - - figure legend:Fig. 1A|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2020/02/27 2020/06/12 - rogid:1vbWq9QaTg7Nm56KJy7HKUoxWj49606 - false - sufficient binding region:306-764|sufficient binding region:70-176(IPR001849)|glutathione s tranferase tag:?-? - - psi-mi:"MI:0421"(identification by antibody) psi-mi:"MI:0421"(identification by antibody) chebi:"CHEBI:18348" uniprotkb:Q9BXB5 intact:EBI-1257123 intact:EBI-2511286|ensembl:ENSP00000379804|uniprotkb:Q9BTU5|uniprotkb:B4E212 psi-mi:1-phosphatidyl-1d-myo-inositol 4,5-bisphosphate(display_short)|psi-mi:"CHEBI:18348"(display_long) psi-mi:osb10_human(display_long)|uniprotkb:OSBPL10(gene name)|psi-mi:OSBPL10(display_short)|uniprotkb:ORP10(gene name synonym)|uniprotkb:OSBP9(gene name synonym) psi-mi:"MI:0049"(filter binding) Nissilä et al. (2012) imex:IM-28060|pubmed:22906437 taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0486"(UniProt) intact:EBI-25437510|imex:IM-28060-5 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0328"(small molecule) psi-mi:"MI:0326"(protein) - ensembl:ENSG00000144645(gene)|ensembl:ENST00000396556(transcript)|go:"GO:0001786"(phosphatidylserine binding)|go:"GO:0005548"(phospholipid transporter activity)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0015248"(sterol transporter activity)|go:"GO:0015485"(cholesterol binding)|go:"GO:0016020"(membrane)|go:"GO:0032934"(sterol binding)|go:"GO:0036150"(phosphatidylserine acyl-chain remodeling)|go:"GO:0043231"(intracellular membrane-bounded organelle)|interpro:IPR000648(Oxysterol-binding protein)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR018494|interpro:IPR037239|interpro:IPR041680|reactome:R-HSA-1482801|refseq:NP_001167531.1|refseq:NP_060254.2 - - - figure legend:Fig. 1A|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2020/02/27 2020/06/12 - rogid:1vbWq9QaTg7Nm56KJy7HKUoxWj49606 - false - sufficient binding region:306-764|sufficient binding region:70-176(IPR001849)|glutathione s tranferase tag:?-? - - psi-mi:"MI:0421"(identification by antibody) psi-mi:"MI:0421"(identification by antibody) chebi:"CHEBI:16500" uniprotkb:Q9BXB5 intact:EBI-1257117 intact:EBI-2511286|ensembl:ENSP00000379804|uniprotkb:Q9BTU5|uniprotkb:B4E212 psi-mi:pi5p(display_short)|psi-mi:"CHEBI:16500"(display_long) psi-mi:osb10_human(display_long)|uniprotkb:OSBPL10(gene name)|psi-mi:OSBPL10(display_short)|uniprotkb:ORP10(gene name synonym)|uniprotkb:OSBP9(gene name synonym) psi-mi:"MI:0049"(filter binding) Nissilä et al. (2012) imex:IM-28060|pubmed:22906437 taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0486"(UniProt) intact:EBI-25437523|imex:IM-28060-25 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0328"(small molecule) psi-mi:"MI:0326"(protein) - ensembl:ENSG00000144645(gene)|ensembl:ENST00000396556(transcript)|go:"GO:0001786"(phosphatidylserine binding)|go:"GO:0005548"(phospholipid transporter activity)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0015248"(sterol transporter activity)|go:"GO:0015485"(cholesterol binding)|go:"GO:0016020"(membrane)|go:"GO:0032934"(sterol binding)|go:"GO:0036150"(phosphatidylserine acyl-chain remodeling)|go:"GO:0043231"(intracellular membrane-bounded organelle)|interpro:IPR000648(Oxysterol-binding protein)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR018494|interpro:IPR037239|interpro:IPR041680|reactome:R-HSA-1482801|refseq:NP_001167531.1|refseq:NP_060254.2 - - - figure legend:Fig. 1A|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2020/02/27 2020/06/12 - rogid:1vbWq9QaTg7Nm56KJy7HKUoxWj49606 - false - sufficient binding region:306-764|glutathione s tranferase tag:?-? - - psi-mi:"MI:0421"(identification by antibody) psi-mi:"MI:0421"(identification by antibody) chebi:"CHEBI:16618" uniprotkb:Q9BXB5 intact:EBI-1257125 intact:EBI-2511286|ensembl:ENSP00000379804|uniprotkb:Q9BTU5|uniprotkb:B4E212 psi-mi:1-phosphatidyl-1d-myo-inositol 3,4,5-trisphosphate(display_short)|psi-mi:"CHEBI:16618"(display_long) psi-mi:osb10_human(display_long)|uniprotkb:OSBPL10(gene name)|psi-mi:OSBPL10(display_short)|uniprotkb:ORP10(gene name synonym)|uniprotkb:OSBP9(gene name synonym) psi-mi:"MI:0049"(filter binding) Nissilä et al. (2012) imex:IM-28060|pubmed:22906437 taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0486"(UniProt) intact:EBI-25437538|imex:IM-28060-7 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0328"(small molecule) psi-mi:"MI:0326"(protein) - ensembl:ENSG00000144645(gene)|ensembl:ENST00000396556(transcript)|go:"GO:0001786"(phosphatidylserine binding)|go:"GO:0005548"(phospholipid transporter activity)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0015248"(sterol transporter activity)|go:"GO:0015485"(cholesterol binding)|go:"GO:0016020"(membrane)|go:"GO:0032934"(sterol binding)|go:"GO:0036150"(phosphatidylserine acyl-chain remodeling)|go:"GO:0043231"(intracellular membrane-bounded organelle)|interpro:IPR000648(Oxysterol-binding protein)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR018494|interpro:IPR037239|interpro:IPR041680|reactome:R-HSA-1482801|refseq:NP_001167531.1|refseq:NP_060254.2 - - - figure legend:Fig. 1A|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2020/02/27 2020/06/12 - rogid:1vbWq9QaTg7Nm56KJy7HKUoxWj49606 - false - sufficient binding region:306-764|glutathione s tranferase tag:?-? - - psi-mi:"MI:0421"(identification by antibody) psi-mi:"MI:0421"(identification by antibody) chebi:"CHEBI:16337" uniprotkb:Q9BXB5 intact:EBI-1263288 intact:EBI-2511286|ensembl:ENSP00000379804|uniprotkb:Q9BTU5|uniprotkb:B4E212 psi-mi:phosphatidic acids(display_short)|psi-mi:"CHEBI:16337"(display_long) psi-mi:osb10_human(display_long)|uniprotkb:OSBPL10(gene name)|psi-mi:OSBPL10(display_short)|uniprotkb:ORP10(gene name synonym)|uniprotkb:OSBP9(gene name synonym) psi-mi:"MI:0049"(filter binding) Nissilä et al. (2012) imex:IM-28060|pubmed:22906437 taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0486"(UniProt) intact:EBI-25437549|imex:IM-28060-9 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0328"(small molecule) psi-mi:"MI:0326"(protein) - ensembl:ENSG00000144645(gene)|ensembl:ENST00000396556(transcript)|go:"GO:0001786"(phosphatidylserine binding)|go:"GO:0005548"(phospholipid transporter activity)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0015248"(sterol transporter activity)|go:"GO:0015485"(cholesterol binding)|go:"GO:0016020"(membrane)|go:"GO:0032934"(sterol binding)|go:"GO:0036150"(phosphatidylserine acyl-chain remodeling)|go:"GO:0043231"(intracellular membrane-bounded organelle)|interpro:IPR000648(Oxysterol-binding protein)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR018494|interpro:IPR037239|interpro:IPR041680|reactome:R-HSA-1482801|refseq:NP_001167531.1|refseq:NP_060254.2 - - - figure legend:Fig. 1A|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2020/02/27 2020/06/12 - rogid:1vbWq9QaTg7Nm56KJy7HKUoxWj49606 - false - sufficient binding region:306-764|glutathione s tranferase tag:?-? - - psi-mi:"MI:0421"(identification by antibody) psi-mi:"MI:0421"(identification by antibody) chebi:"CHEBI:18303" uniprotkb:Q9BXB5 intact:EBI-1607324 intact:EBI-2511286|ensembl:ENSP00000379804|uniprotkb:Q9BTU5|uniprotkb:B4E212 psi-mi:phosphatidyl-l-serines(display_short)|psi-mi:"CHEBI:18303"(display_long) psi-mi:osb10_human(display_long)|uniprotkb:OSBPL10(gene name)|psi-mi:OSBPL10(display_short)|uniprotkb:ORP10(gene name synonym)|uniprotkb:OSBP9(gene name synonym) psi-mi:"MI:0049"(filter binding) Nissilä et al. (2012) imex:IM-28060|pubmed:22906437 taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0486"(UniProt) intact:EBI-25437557|imex:IM-28060-11 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0328"(small molecule) psi-mi:"MI:0326"(protein) - ensembl:ENSG00000144645(gene)|ensembl:ENST00000396556(transcript)|go:"GO:0001786"(phosphatidylserine binding)|go:"GO:0005548"(phospholipid transporter activity)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0015248"(sterol transporter activity)|go:"GO:0015485"(cholesterol binding)|go:"GO:0016020"(membrane)|go:"GO:0032934"(sterol binding)|go:"GO:0036150"(phosphatidylserine acyl-chain remodeling)|go:"GO:0043231"(intracellular membrane-bounded organelle)|interpro:IPR000648(Oxysterol-binding protein)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR018494|interpro:IPR037239|interpro:IPR041680|reactome:R-HSA-1482801|refseq:NP_001167531.1|refseq:NP_060254.2 - - - figure legend:Fig. 1A|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2020/02/27 2020/06/12 - rogid:1vbWq9QaTg7Nm56KJy7HKUoxWj49606 - false - sufficient binding region:306-764|glutathione s tranferase tag:?-? - - psi-mi:"MI:0421"(identification by antibody) psi-mi:"MI:0421"(identification by antibody) chebi:"CHEBI:16113" uniprotkb:Q9BXB5 intact:EBI-2368700 intact:EBI-2511286|ensembl:ENSP00000379804|uniprotkb:Q9BTU5|uniprotkb:B4E212 psi-mi:cholesterol(display_short)|psi-mi:"CHEBI:16113"(display_long) psi-mi:osb10_human(display_long)|uniprotkb:OSBPL10(gene name)|psi-mi:OSBPL10(display_short)|uniprotkb:ORP10(gene name synonym)|uniprotkb:OSBP9(gene name synonym) psi-mi:"MI:0400"(affinity technology) Nissilä et al. (2012) imex:IM-28060|pubmed:22906437 taxid:-2(chemical synthesis)|taxid:-2("Chemical synthesis (Chemical synthesis)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0486"(UniProt) intact:EBI-25437571|imex:IM-28060-13 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0328"(small molecule) psi-mi:"MI:0326"(protein) - ensembl:ENSG00000144645(gene)|ensembl:ENST00000396556(transcript)|go:"GO:0001786"(phosphatidylserine binding)|go:"GO:0005548"(phospholipid transporter activity)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0015248"(sterol transporter activity)|go:"GO:0015485"(cholesterol binding)|go:"GO:0016020"(membrane)|go:"GO:0032934"(sterol binding)|go:"GO:0036150"(phosphatidylserine acyl-chain remodeling)|go:"GO:0043231"(intracellular membrane-bounded organelle)|interpro:IPR000648(Oxysterol-binding protein)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR018494|interpro:IPR037239|interpro:IPR041680|reactome:R-HSA-1482801|refseq:NP_001167531.1|refseq:NP_060254.2 - - - figure legend:Fig. 1B|comment:"Deletion of the region 412–415 (amino acid residues DLTK) resulted in an equal or even higher cholesterol extraction capacity than the wild-type OSBPL10."|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2020/02/27 2020/06/11 - rogid:1vbWq9QaTg7Nm56KJy7HKUoxWj49606 - false 3h radiolabel:?-? sufficient binding region:306-764|glutathione s tranferase tag:?-? - - psi-mi:"MI:0866"(tag visualisation) psi-mi:"MI:0866"(tag visualisation) uniprotkb:Q96SU4 uniprotkb:Q9BXB5 intact:EBI-2511368|ensembl:ENSP00000407168|uniprotkb:Q6IA67|uniprotkb:Q9H9X2|uniprotkb:Q96SK4|uniprotkb:B1AKJ8|uniprotkb:Q5TFC0|uniprotkb:Q8NB17|uniprotkb:Q8TAS8|uniprotkb:D3DQ31|uniprotkb:B3KPQ4|uniprotkb:Q86YQ3 intact:EBI-2511286|ensembl:ENSP00000379804|uniprotkb:Q9BTU5|uniprotkb:B4E212 psi-mi:osbl9_human(display_long)|uniprotkb:OSBPL9(gene name)|psi-mi:OSBPL9(display_short)|uniprotkb:ORP9(gene name synonym)|uniprotkb:OSBP4(gene name synonym) psi-mi:osb10_human(display_long)|uniprotkb:OSBPL10(gene name)|psi-mi:OSBPL10(display_short)|uniprotkb:ORP10(gene name synonym)|uniprotkb:OSBP9(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Nissilä et al. (2012) imex:IM-28060|pubmed:22906437 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0486"(UniProt) intact:EBI-25466654|imex:IM-28060-15 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000117859(gene)|ensembl:ENST00000428468(transcript)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0006699"(bile acid biosynthetic process)|go:"GO:0015248"(sterol transporter activity)|go:"GO:0016020"(membrane)|go:"GO:0031902"(late endosome membrane)|go:"GO:0032934"(sterol binding)|go:"GO:0043231"(intracellular membrane-bounded organelle)|interpro:IPR000648(Oxysterol-binding protein)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR018494|interpro:IPR037239|mint:Q96SU4|reactome:R-HSA-192105|refseq:XP_011538905.1|refseq:XP_011538906.1|refseq:NP_078862.4|refseq:NP_683702.1|refseq:NP_683703.1|refseq:NP_683705.1|refseq:NP_683706.3|refseq:NP_683704.2|refseq:NP_683707.3|refseq:XP_006710386.1|refseq:XP_006710387.1|refseq:XP_006710388.1|refseq:XP_006710389.1|refseq:NP_001317509.1|refseq:XP_016855708.1|refseq:XP_016855709.1|refseq:XP_016855710.1 ensembl:ENSG00000144645(gene)|ensembl:ENST00000396556(transcript)|go:"GO:0001786"(phosphatidylserine binding)|go:"GO:0005548"(phospholipid transporter activity)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0015248"(sterol transporter activity)|go:"GO:0015485"(cholesterol binding)|go:"GO:0016020"(membrane)|go:"GO:0032934"(sterol binding)|go:"GO:0036150"(phosphatidylserine acyl-chain remodeling)|go:"GO:0043231"(intracellular membrane-bounded organelle)|interpro:IPR000648(Oxysterol-binding protein)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR018494|interpro:IPR037239|interpro:IPR041680|reactome:R-HSA-1482801|refseq:NP_001167531.1|refseq:NP_060254.2 - - - figure legend:Fig 5D|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-huh7)|taxid:9606(Homo sapiens hepatoma cell line established from a hepatocellular carcinoma) - 2020/02/27 2020/03/09 rogid:2XLQ0JD4BEKGoyiwd/63YTmyVlE9606 rogid:1vbWq9QaTg7Nm56KJy7HKUoxWj49606 rigid:J/pRd5K8HgFMJ/42JsS4vR2g3EM false xpress tag:n-n green fluorescent protein tag:n-n - - psi-mi:"MI:0705"(anti tag western blot) psi-mi:"MI:0705"(anti tag western blot) uniprotkb:Q96SU4 uniprotkb:Q9BXB5 intact:EBI-2511368|ensembl:ENSP00000407168|uniprotkb:Q6IA67|uniprotkb:Q9H9X2|uniprotkb:Q96SK4|uniprotkb:B1AKJ8|uniprotkb:Q5TFC0|uniprotkb:Q8NB17|uniprotkb:Q8TAS8|uniprotkb:D3DQ31|uniprotkb:B3KPQ4|uniprotkb:Q86YQ3 intact:EBI-2511286|ensembl:ENSP00000379804|uniprotkb:Q9BTU5|uniprotkb:B4E212 psi-mi:osbl9_human(display_long)|uniprotkb:OSBPL9(gene name)|psi-mi:OSBPL9(display_short)|uniprotkb:ORP9(gene name synonym)|uniprotkb:OSBP4(gene name synonym) psi-mi:osb10_human(display_long)|uniprotkb:OSBPL10(gene name)|psi-mi:OSBPL10(display_short)|uniprotkb:ORP10(gene name synonym)|uniprotkb:OSBP9(gene name synonym) psi-mi:"MI:0809"(bimolecular fluorescence complementation) Nissilä et al. (2012) imex:IM-28060|pubmed:22906437 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0486"(UniProt) intact:EBI-25466698|imex:IM-28060-17 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000117859(gene)|ensembl:ENST00000428468(transcript)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0006699"(bile acid biosynthetic process)|go:"GO:0015248"(sterol transporter activity)|go:"GO:0016020"(membrane)|go:"GO:0031902"(late endosome membrane)|go:"GO:0032934"(sterol binding)|go:"GO:0043231"(intracellular membrane-bounded organelle)|interpro:IPR000648(Oxysterol-binding protein)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR018494|interpro:IPR037239|mint:Q96SU4|reactome:R-HSA-192105|refseq:XP_011538905.1|refseq:XP_011538906.1|refseq:NP_078862.4|refseq:NP_683702.1|refseq:NP_683703.1|refseq:NP_683705.1|refseq:NP_683706.3|refseq:NP_683704.2|refseq:NP_683707.3|refseq:XP_006710386.1|refseq:XP_006710387.1|refseq:XP_006710388.1|refseq:XP_006710389.1|refseq:NP_001317509.1|refseq:XP_016855708.1|refseq:XP_016855709.1|refseq:XP_016855710.1 ensembl:ENSG00000144645(gene)|ensembl:ENST00000396556(transcript)|go:"GO:0001786"(phosphatidylserine binding)|go:"GO:0005548"(phospholipid transporter activity)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0015248"(sterol transporter activity)|go:"GO:0015485"(cholesterol binding)|go:"GO:0016020"(membrane)|go:"GO:0032934"(sterol binding)|go:"GO:0036150"(phosphatidylserine acyl-chain remodeling)|go:"GO:0043231"(intracellular membrane-bounded organelle)|interpro:IPR000648(Oxysterol-binding protein)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR018494|interpro:IPR037239|interpro:IPR041680|reactome:R-HSA-1482801|refseq:NP_001167531.1|refseq:NP_060254.2 go:"GO:0005794"(Golgi apparatus) - - figure legend:Fig 5A|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-huh7)|taxid:9606(Homo sapiens hepatoma cell line established from a hepatocellular carcinoma) - 2020/02/27 2020/03/09 rogid:2XLQ0JD4BEKGoyiwd/63YTmyVlE9606 rogid:1vbWq9QaTg7Nm56KJy7HKUoxWj49606 rigid:J/pRd5K8HgFMJ/42JsS4vR2g3EM false venus c-terminal fragment:?-? venus n-terminal fragment:?-? - - psi-mi:"MI:0705"(anti tag western blot) psi-mi:"MI:0705"(anti tag western blot) uniprotkb:Q96SU4 uniprotkb:Q9BXB4 intact:EBI-2511368|ensembl:ENSP00000407168|uniprotkb:Q6IA67|uniprotkb:Q9H9X2|uniprotkb:Q96SK4|uniprotkb:B1AKJ8|uniprotkb:Q5TFC0|uniprotkb:Q8NB17|uniprotkb:Q8TAS8|uniprotkb:D3DQ31|uniprotkb:B3KPQ4|uniprotkb:Q86YQ3 intact:EBI-2514786|intact:EBI-28979243|ensembl:ENSP00000296220|uniprotkb:A8K9I7 psi-mi:osbl9_human(display_long)|uniprotkb:OSBPL9(gene name)|psi-mi:OSBPL9(display_short)|uniprotkb:ORP9(gene name synonym)|uniprotkb:OSBP4(gene name synonym) psi-mi:osb11_human(display_long)|uniprotkb:OSBPL11(gene name)|psi-mi:OSBPL11(display_short)|uniprotkb:ORP11(gene name synonym)|uniprotkb:OSBP12(gene name synonym) psi-mi:"MI:0809"(bimolecular fluorescence complementation) Nissilä et al. (2012) imex:IM-28060|pubmed:22906437 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0486"(UniProt) intact:EBI-25466730|imex:IM-28060-19 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000117859(gene)|ensembl:ENST00000428468(transcript)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0006699"(bile acid biosynthetic process)|go:"GO:0015248"(sterol transporter activity)|go:"GO:0016020"(membrane)|go:"GO:0031902"(late endosome membrane)|go:"GO:0032934"(sterol binding)|go:"GO:0043231"(intracellular membrane-bounded organelle)|interpro:IPR000648(Oxysterol-binding protein)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR018494|interpro:IPR037239|mint:Q96SU4|reactome:R-HSA-192105|refseq:XP_011538905.1|refseq:XP_011538906.1|refseq:NP_078862.4|refseq:NP_683702.1|refseq:NP_683703.1|refseq:NP_683705.1|refseq:NP_683706.3|refseq:NP_683704.2|refseq:NP_683707.3|refseq:XP_006710386.1|refseq:XP_006710387.1|refseq:XP_006710388.1|refseq:XP_006710389.1|refseq:NP_001317509.1|refseq:XP_016855708.1|refseq:XP_016855709.1|refseq:XP_016855710.1 ensembl:ENSG00000144909(gene)|ensembl:ENST00000296220(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0010890"(positive regulation of sequestering of triglyceride)|go:"GO:0015248"(sterol transporter activity)|go:"GO:0016020"(membrane)|go:"GO:0031902"(late endosome membrane)|go:"GO:0032934"(sterol binding)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0045444"(fat cell differentiation)|interpro:IPR000648(Oxysterol-binding protein)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR018494|interpro:IPR037239|mint:Q9BXB4|rcsb pdb:2D9X|reactome:R-HSA-9013407|ensembl:ENSP00000296220|refseq:NP_073613.2 go:"GO:0005794"(Golgi apparatus) - - figure legend:Fig 5B|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-huh7)|taxid:9606(Homo sapiens hepatoma cell line established from a hepatocellular carcinoma) - 2020/02/27 2020/03/09 rogid:2XLQ0JD4BEKGoyiwd/63YTmyVlE9606 rogid:KkLAr8dp83zeiK8iQg61QPEm2fs9606 rigid:JrHisE0dt/Ll3lArV9nUjuvptRY false venus c-terminal fragment:?-? venus n-terminal fragment:?-? - - psi-mi:"MI:0705"(anti tag western blot) psi-mi:"MI:0705"(anti tag western blot)